This information has been assembled for
use by NHLBI staff and the National
Heart, Lung, and Blood Advisory Council.
Questions regarding any of this information
should be directed to the Information
Systems Branch— OPPE-NHLBI.
J
1
DISCRIMINATION PROHIBITED: Under provisions of applicable
public laws enacted by Congress since 1964, no person in the
United States shall, on the ground of race, color, national origin, sex
or handicap, be excluded from participation in, be denied the benefits
of, or be subjected to discrimination under any program or activity
receiving Federal financial assistance. In addition, Executive Order
1 1 141 prohibits discrimination on the basis of age by contractors and
subcontractors in the performance of Federal contracts. Therefore,
the National Heart, Lung, and Blood Institute must be operated
in compliance with these laws and executive order.
p^ew^o
i^u-
Subject Index
of
Current Research Grants and Contracts
Administered by
The National
Heart/
Lung,&
Institute
Updated
December 1978
DHEW Publication No. (NIH) 79-705
U.S. DEPARTMENT OF HEALTH, EDUCATION, AND WELFARE
Public Health Service National Institutes of Health
^ir^
L/.?i
«v,v^ i-m
Subject Index of
Current Research Grants and Contracts Administered
by the National Heart, Lung, and Blood Institute
Table of Contents
Introduction
Definition of Prefixes Used in Project Numbers .
Initiai Review Groups
Aiphabeticai Listing of Subjects
Project identification and Investigator Address
Alphabetical Listing of Investigators
Page
V
■ •
VII
ix
1
523
585
III
i
i
INTRODUCTION
This publication contains information on research grants and contracts supported by the
National Heart, Lung, and Blood Institute. It is published In the interest of providing tinnely
information about the research supported by the National Heart, Lung, and Blood institute
(grants and contracts active December 1978) and with an awareness that information for a
few projects active at this time was not available.
This index is prepared in cooperation with the Research Documentation Section, Statistics
and Analysis Branch, Division of Research Grants, National Institutes of Health. It is based
on the indexing of the System for the Computerized Retrieval of Information on Scientific
Projects (CRISP).
Project Identifiers
Projects (grants and contracts) are identified in this index through a series of codes (see
Definitions of Prefixes). Other codes designate the initial review groups (see Initial Review
Groups). They appear in the various sections, as illustrated by the diagram below.
Grant
Contract
P01
HL
12345
-08
007
(HLBA)
N01
HV
12345
-02
(HCRG)
For a grant, the suffix is the approximate length of time a project has been supported; for a
contract, the number of modifications.
The following mnemonics are used as Institute designations:
National Heart, Lung, and Blood Institute
Division of Blood Diseases and Resources
Division of Intramural Research
Office of the Director
Division of Lung Diseases
Division of Heart and Vascular Diseases
Alphabetical Listing of Subjects
Subject headings are listed alphabetically. Under each subject heading relevant projects are
listed numerically with their titles.
In the case of large grants, the grant number is repeated under each subject heading for each
relevant subproject, together with the appropriate subproject number.
Grants:
HL
Contracts:
HB
HI
HO
HR
HV
Project Identification and Investigator Address
Projects are arranged alphabetically according to the Institute designator (HB, HI, HL, HO, HR,
HV). For each of these codes, projects are listed in numerical order.
Several project directors within a parent grant may be listed. The institution address appears
only with the first entry. kk^^c =>
Alphabetical Listing of Investigators
The names of the principal investigators of active grants or contracts are listed alpha-
betically. In the case of large grants where there are several subprojects, the name of one in-
vestigator may be repeated several times. Numbers of subprojects which have been
disapproved in the review process, or which have been completed, do not appear in this
General
By using the last two sections of this index in conjunction with each other, it is possible to
determine who is doing what kind of research and where.
i
VI
DEFINITIONS OF PREFIXES USED IN PROJECT NUMBERS
N01-Research and Project Contracts: To develop and/or apply new knowledge or to test,
screen, or evaluate a product, material, device or component for use by the scientific
community.
POI-Research Program Project Grants: For support of a multicategorical approach and usu-
ally long-term program of research activity. These grants are usually directed toward
a limited range of problems within a specific category, having a central research
focus.
P50-Speclalized Centers of Research: To support any part of the full range of basic to clini-
cal research and development related to cardiovascular, pulmonary and blood
diseases. These grants differ from program project grants in that they are usually
developed in response to a program announcement and subsequently receive con-
tinuous staff attention.
P60-Comprehensive Centers: To support a multipurpose unit with the following objec-
tives: fostering biomedical research and development both at the fundamental and
clinical levels; community education, screening, and counseling programs; education
of medical and allied health professionals; demonstration program on diagnosis,
prevention and treatment of cardiovascular, pulmonary and blood diseases.
R01 -Traditional Research Grants: To support a circumscribed project to be carried out
under the direction of a named principal investigator In an area representing his or
her specific interest and competencies.
R10-Cooperatlve Clinical Research: To support clinical evaluation of various methods of
therapy in specific disease areas. These are usually collaborative programs between
sponsoring institutions and principal investigators, and usually conducted under a
formal protocol.
R13-Conference Grant: To support international or national meetings, conferences and
workshops.
R18-Research Demonstration and Dissemination Projects: To provide support designed to
develop, test, and evaluate health service activities, and to foster the application of
existing knowledge for the control of categorical diseases.
R23-Young Investigator Award: A program of the National Heart, Lung, and Blood Institute
to support basic and clinical studies for trained investigators to initiate new programs
in the cardiovascular, pulmonary and blood diseases areas.
R25-High Blood Pressure Education Research Program: A program with the following objec-
tives: to foster research that would identify the characteristics of a hypertensive
individual that are related to, or are suspected of relating to, adherence behavior; to
develop educational interventions aimed at altering the behavioral characteristics of
hypertensives to bring about immediate and long-term adherence to therapy.
VII
iJLA^WHIM^flES H^V^^lJ
INITIAL REVIEW GROUPS
qtudv sections and committees responsible for the initial technical review of research
glant^ppllcations are listed with their abbreviations. Contracts are reviewed by ad hoc
peer review groups.
AFY — Applied Physiology and Orthopedics Study Section
ALC — Alcohol Research Review Committee
ALY — Allergy and Immunology Study Section
AR — Animal Resources Advisory Committee
BBCA - Biophysics and Biophysical Chemistry A Study Section
BBCB - Biophysics and Biophysical Chemistry B Study Section
BCM — Biomedical Communications Study Section
BIO — Biochemistry Study Section
BM — Bacteriology and Mycology Study Section
BMT - Bioanalytical and Metaliobiochemistry Study Section
BPS — Biopsychoiogy Study Section
CBY — Cell Biology Study Section
CLR — General Clinical Research Centers Committee
CMS — Communicative Sciences Study Section
CTY — Molecular Cytology Study Section
CVA — Cardiovascular and Pulmonary Study Section
CVB — Cardiovascular and Renal Study Section
EDC — Epidemiology and Disease Control Study Section
END — Endocrinology Study Section
ET — Experimental Therapeutics Study Section
EVR — Experimental Virology Study Section
GEN — Genetics Study Section
GmA — General Medicine A Study Section
GMB — General Medicine B Study Section
HBP - National High Blood Pressure Education Research Program Committee
HCRG - Heart, Lung, and Blood Peer Review Groups for Contracts
HOT — Health Care Technology Study Section
HED - Human Embryology and Development Study Section
HEM — Hematology Study Section
HLBA - Heart, Lung, and Blood Research Review Committee A
HLBB - Heart, Lung, and Blood Research Review Committees
HSDG - Health Services Developmental Grants Study Section
HUD — Human Development Study Section
1MB — Immunobiology Study Section
IMS — Immunological Sciences Study Section
MCB — Microbial Chemistry Study Section
MBY — Molecular Biology Study Section
MCHA — Medicinal Chemistry A Study Section
MET — Metabolism Study Section
NEUA — Neurology A Study Section
NEUB — Neurology B Study Section
IX
NSS
NTN
PCB
PC
PHRA
PHY
PTHA
PTHB
PTR
RAD
REB
SAT
SB
SRC
SSS
TMP
TOX
VISA
VISB
VR
— No Initial Review Group
— Nutrition Study Section
— Pathobiological Chemistry Study Section
— Physiological Chemistry Study Section
— Pharmacology Study Section
— Physiology Study Section
— Pathology A Study Section
— Pathology B Study Section
— Pharmacology-Toxicology Review Committee
— Radiation Study Section
— Reproductive Biology Study Section
— Surgery, Anesthesiology and Trauma Study Section
— Surgery and Bioengineering Study Section
— Special Review Committee
— Special Study Section
— Tropical Medicine and Parasitology Study Section
— Toxicology Study Section
— Visual Sciences A Study Section
— Visual Sciences B Study Section
— Virology Study Section
■m
ABD
ABDOMEN
SU BODY REGIONS. ABOOMfN
ABDOMINAL ARTERIES
S(f CAKOIOVASCIIUR SYSIIM. ARTERIES, ABOOMINAl
ARURItS
ABETALIPOPROTEINEMIA
SEE METABOUC DISORDERS INBORN,
HYPOIIPOPROIEINEMIAS fAMIllAI.
ABflAllPOPROHINEMIA
ABO HEMOLYTIC DISEASE NEWBORN
SEE BLOOD GROUP INCOMPAIIBIUIY PERINAIAl, ABO
HEMOIYIIC DISEASE NEWBORN
ABO(H) SYSTEM
SEE BLOOD GROUPS. ABO (H) SYSTEM
ABSCESS
SEE DISEASES. PATHOLOGIC PROCESSES, INFLAMMATION.
ABSCESS
ABSORPTION
SEE BIOLOGICAL TRANSPORT, MEMBRANE PERMEABILITY
AND TRANSPORT
ABSORPTION OF DIETARY NUTRIENTS
SEE GASTROINTESTINAL FUNCTION. ABSORPTION TRANSPORT.
DIETARY NUTRIENTS
AC-GLOBULIN
SEE BLOOD COAGULATION. FACTOR V
ACADEMIC ACHIEVEMENT
SEE PSYCHOLOGY. PERFORMANCE. ACADEMIC ACHIEVEMENT
ACANTHROCYTOSIS (ABETALIPOPROTEINEMIA)
SEE METABOLIC DISORDERS INBORN.
HYPOLIPOPROTEINEMIAS FAMILIAL.
ABETALIPOPROTEINEMIA
ACAPNIA
SEE RESPIRATORY GAS LEVELS. HYPOCAPNIA
ACATALASEMIA
SEE METABOLIC DISORDERS INBORN. ACATALASEMIA
ACATALASIA
SEE METABOLIC DISORDERS INBORN. ACATAUSEMIA
ACCELERATION
SEE ENVIRONMENT. GRAVITY-MOTION
ACCELERATOR GLOBULIN
SEE BLOOD COAGUUTION. FACTOR V
ACCELERATORS (PARTICLE)
SEE RADIATION. PARTICLE ACCELERATORS
ACCELERIN
SEE BLOOD COAGULATION. FACTOR V
ACCIDENTAL SUFFOCATION
SEE INJURIES. ACCIDENTS. SUFFOCATION
ACCUMATIZATION
SEE ENVIRONMENT. ADAPTATION. ACCLIMATIZATION
ACETALDEHYDE
SEE ALDEHYDES. ACETALDEHYDE
ACET AMIDES
SEE AMIDES. ACETAMIDES
2-ACETAMIDO-ETHYL(P-CHLOROPHENYL)(N-
TRIFLUOROMETHYL PHENYL PHENOXY)
ACETATE
SEE PHENOXYACETIC ACIDS. HALOFENATE
ACETATE:COA LIGASE (AMP)
SEE ACID-THIOL LIGASES. ACETATE:COA LIGASE (AMP)
ACETATES
SEE FATTY ACIDS. ACETATES
ACETAZOLAMIDE
SEE SULFONAMIDES. ACETAZOLAMIDE
ACETOACETATES
SEE FATTY ACIDS. ACETOACETATES
ACETOPHENETIDIN
SEE PHENYUMIDES. ACETOPHENETIDIN
ACETYLATION
SEE ACYLS. ACYLATION. ACETYLATION
ACETYLCHOLINE
SEE CHOLINE. ACETYLCHOLINE
ACETYLCHOLINESTERASE
SEE CHOLINE ESTERASES, ACETYLCHOLINESTERASE
ACETYL COA
SEE COENZYMES. COENZYME A. ACETYLCOA
ACETYL-COA CARBOXYLASE
SEE CARBON-CARBON LIGASES. ACETYL-COA CARBOXYLASE
1
ACETYl-C0A:C05 LIGASE (ADP)
SH CARBON CARBON IICASI S. ACI lYl COA CARBOXYIASI
ACETYL-COA SYNTHETASE (AMP)
SEl ACID IHIOl IICASIS. AtllAIf COA IICASI (AMP)
ACETYL COA TRANSACETYLASE
SEE IRANSACYIASIS, ACI lYl COA IRANSACIIYLASl
ACETYL-COENZYME A
SEE COENZYMES, COl N/YME A, ACETYLCOA
ACETYLENE COMPOUNDS
SEE ALKYNES
N-ACETYLGALACTOSAMINE
SEE HEXOSES, GAIACTOSAMINES, N ACETYLGALACTOSAMINE
N-ACETYLGIUCOSAMINIDASES
SEE CARBOHYDRASES, N ACETYLCLUCOSAMINIDASES
BETA-N-ACETYLHEXOSAMINIDASE
SEE CARBOHYDRASES, HEXOSAMINIDASES
N-ACETYU\AURAMIDE GLUCANOHYDROLASE
SEE CARBOHYDRASES LYSOZYME
N-ACETYLNEURAMINIDASE
SEE CARBOHYDRASES, NEURAMINIDASE
ACETYLSALICYLATES
SEE PHENYLCARBOXYLATES, SALICYLATES. ACETYL-
ACETYLTHIOKINASE (AMP)
SEE ACID THIOL LIGASES, ACETATE:COA LIGASE (AMP)
ACHIEVEMENT
SEE PSYCHOLOGY, PERFORMANCE, ACADEMIC ACHIEVEMENT
ACID-AMMONIA LIGASES, L-
GLUTAMATE:AMMONIA LIGASE (ADP)
ROlHL-11822 10 Biophysical studies of macromolecular
interactions (microorganism, human)
ACID-BASE BALANCE
SEE BODY FLUID BALANCE, ACID-BASE
ACID-FAST BACTERIA
SEE BACTERIA, ACID-FAST BACTERIA*
ACID PHOSPHATASE
SEE PHOSPHOMONOESTERASES, ACID PHOSPHATASE
ACID-THIOL LIGASES, ACETATE:COA LIGASE
(AMP)
ROlHL-12399-13 Specific fatty acids and cholesterol
metabolism (gerbils, rats)
ACIDITY OF URINE
SEE URINE ACIDITY
ACIDOSIS
SEE BODY FLUID BALANCE, ACID-BASE, ACIDOSIS
ACIDOSIS, DIABETIC
SEE CARBOHYDRATES METABOLISM DISORDERS, DIABETIC
ACIDOSIS
ACIDOSIS, RESPIRATORY
SEE RESPIRATORY DISORDERS, ACIDOSIS, RESPIRATORY
ACIDOSIS INHIBITORS
SEE BODY FLUID BALANCE, ACID-BASE, ANTIACIDOSIS DRUGS
ACIDOSIS RENAL TUBULAR
SEE METABOLIC DISORDERS (INBORN), RENAL TUBULAR
ACIDOSIS
ACIDS
SEE ACIDS-BASES, ACIDS (GENERAL)
ACIDS-BASES, ACIDS (GENERAL)
SEE ALSO AMINES, HYDROXYLAMINES, HYOROXAMIC ACIDS
SEE ALSO NITRATES
SEE ALSO NUCLEIC ACIDS
SEE ALSO PHOSPHATES
SEE ALSO PHOSPHONATES
SEE ALSO SULFATES
SEE ALSO SULFONATES
ROlHL-18028-03 Absorption of nonvolatile compounds
from the lung
ACIDS-BASES, ACIDS ORGANIC (GENERAL)
ROlHL-04457-20 Cellular aspects of active transport (fish.
rabbits, anurans. turtles)
R23HL-22882-01 Modulation by disease of effect of
furosemide in man
ACIDS-BASES, ALKALIES
ROlHL-20725-02 Mechanisms and cellular functions of ion
transport
ACIDS-BASES, BASES (GENERAL)
SEE ALSO ACIDS-BASES. ALKALIES
SEE ALSO ALCOHOLS
SEE ALSO AMINES
SEE ALSO STEROLS
ROlHL-18028-03 Absorption of nonvolatile compounds
from the lung
ACI
ACIDS-BASES, BUFFERS
POIIIl iri'il U OOl'j Ctllulii ind mol«ful«i
mech^nl•^m^ ut myorirdiil function Ell«ct\ of hypwn
ind uch«mu on ion •«r.h«n|« tnd h«ir1 (unrlion (ribbil«(
ROIHI 17879 09 0007 Pulmoniry lr»n'.por1 inrt
metaboliim in vivo Oimolic compirtminlil model of
btrrior euhanie
•• P50H1 14718 0/ 0018 Pulmontry SCOR Newborn lunf
center V«hole body buHerinj in tcule hypercepnn (do|»)
ROIHI 774/0 01 Lipowme myocardial uptake in infarct
and r.cbcmia (do|\ r«l4, mice)
ACIDS-BASES, HYDROGEN-ION
CONCENTRATION
SEE ALSO BODY flUID BALANCE. ACID BASE
SEE ALSO RESPIRATORY GAS LEVELS, BOHR EFFECT
N01HB62967 02 Red cell distributions in cyanale treated
blood (human, sheep)
ROIHL 00082 30 Transmembrane movements (barnacles,
frogs, rats)
ROIHL 02363 20 Kinetics of water and electrolytes in
shock (dogs, rats)
P01HL0628S 18 0198 Cardiovascular respiratory
physiology and biochemistry Renal tubular secretion of
hydrogen ion (animals)
POIHL 07896 15 0030 Environmental biomedical research
program Narcosis caused by inert gases at raised
pressures (human, animals)
POIHL 07896-15 0043 Environmental biomedical research
program - Effect of hyperbaric oxygen on the lung (human,
rabbits)
POIHL 08899 14 0054 Tolerance to respiratory gases in
health and disease Glucose transport across choroid
plexus (dogs)
ROIHL 12174 11 Ventilation/perfusion distribution in the
lung (human, mammals)
ROlHL-13841 16 Respiration during altitude
acclimati2ation (goats, dogs. rats, rabbits)
POlHL-14388 07 0180 Regulation of the circulation in
pathological states Regulation of cerebral blood flow
(dogs, monkeys)
POlHL-14388 07 0218 Regulation of the circulation in
pathological states - Regional myocardial dyskinesis-Cause
assessment and reduction (dogs)
R01HL14693-07 Survival value of physiological responses
to hypoxia (dogs)
ROlHL-14967-06 Chemoreceptor function in dynamic
ventilatory control (human, dogs)
P60HL 15157-07 0012 Comprehensive center for sickle
cell disease - Sickling and intracellular pH (human)
P60HL-15162-07 0019 Comprehensive sickle cell center -
RBC-Blood rheology in sickle cell anemia and related
disorders (human, animal)
POlHL-15194-07 0006 Pathophysiology of
cardiopulmonary dysfunction - Kinetics of gas exchange-
Velocity of Bohr effect inerythrocytes(human)
POlHL-15194-070009 Pathophysiology of
cardiopulmonary dysfunction - Kinetics of gas exchange-
Diffusion and erythrocytes reaction rates (human, dogs)
POlHL-15194-07 0022 Pathophysiology of
cardiopulmonary dysfunction - Kinetics of gas exchange-
Pulmonary carbon dioxide exchange (dogs)
ROlHL-16421-08 Determinants of RBC deformability and
capillary flow (human, mice)
R01HL-16''90-04 Structural basis of nephron filtration
(rats, rabbits)
POlHL-16878-05 0004 Control of ventilation in health
and disease - Neurotransmitters in the respiratory system
(cats)
P50HL-17670-04 0022 Study of ischemic heart disease -
Myocardial metabolism in hypoxia and recover (rabbit,
toad, dog)
" POlHL-17731-04 0010 Physiological basis of pulmonary
disease - Gas exchange kinetics (dogs)
ROlHL-18519-03 Albumin, endothelium and
hemocompatibility (human, dog, cattle, rabbit)
R23HL-19601-01 Cardiac response to chronic metabolic
acidosis (rats)
POlHL-19737-02 0005 Cellular and molecular aspects of
respiratory physiology - Interaction of respiratory exchanges
and blood gas parameters (human, animals)
** ROlHL-20196-02 Regulation of coronary arterial smooth
muscle
ROlHL-20558-02 Cardiac electrophysiology -Effects of ions
and drugs
R01HL-20720-02 Myocardial protection during
cardiopulmonary bypass (dogs)
P01HL-20994-02 0009 Dynamics of neutrophil elastase in
the lung - Biosynthesis and degradation of elastin in
emphysema (human, hamsters)
POlHL-21016-02 0004 Sickle cell anemia and other
hemoglobinopathies - Kinetics of sickling
POlHL-21016-02 0005 Sickle cell anemia and other
hemoglobinopathies - Ligand kinetics in normal and Hb S
containing erythrocytes (human)
POlHL-21016-02 0006 Sickle cell anemia and other
hemoglobinopathies - Analysis of the oxygen dissociation
curve of Hb S-containing red cells
POlHL-21016-02 0007 Sickle cell anemia and other
hemoglobinopathies - Cellular determinants of red cell
sickling
(contd)
•Excludes routine metliodology OR covers only general prajeds which preclude
"Oriented significantly to above subiect.
indexing at the specific level.
M Grant has subpiojects describing specific research aspects.
See Appendix for investigator's name and grant number.
ACI
ROlHL-2 11 58-02 Cardiac receptors with vagal Cfiber
afferents (cats)
R23HL-21434-02 Intrinsic control of coronary blood flow by
chemicals (guinea pigs)
R23HL-21901-01 Hypertension, microvascular control and
exercise (rats)
ROlHL-22008-01 Lett ventrivular calcium content and
contractility (rats)
ROlHL-22080-01 Phosphorus NMR studies on cardiac
tissue (rats, rabbits)
ROlHL-22231-02 Modulation of calcium control of cardiac
myofibrils (rats)
ROlHL-22259-01 Modification of susceptibility to oxygen
poisoning (rats)
ROlHL-22315-01 Intraoperative cardiac oxygen supply-
demand (dogs, rabbits, rats)
ROlHL-22500-01 Conversion of choline to
phosphatidylcholine in lung (rabbits, pigs)
ROlHL-22568-01 pH effect in heart cells-Influence of
cardiac drugs (tissue culture, rats)
R23HL-22575-01 Factors modifying cardiac digoxin effects
and content (dogs, cats)
POlHL-22619-01 0005 Cellular mechanisms of heart
failure - Molecular mechanism of regulation of cardiac
muscle contraction (cattle)
ROlHL-23900-01 Mechanical measurement of cell
membrane viscosity (human)
ACIDS-BASES, ISOELECTRIC POINT
NOlHR-72923-01 Cystic fibrosis factor identification and
quantification (human)
ACONINE TYPE ALKALOIDS
SEE ALKALOIDS, ACONINE TYPE
ACONITUM ACONINE TYPE ALKALOIDS
SEE ALKALOIDS, ACONINE TYPE
ACOUSTIC HOLOGRAPHY
SEE OPTICS. PHOTOGRAPHY, HOLOGRAPHY, ACOUSTIC*
ACOUSTIC MICROSCOPY
SEE OPTICS, MICROSCOPY, ULTRASONIC*
ACRIDINES
ROIHLI 7702-04 Electro^ptical dyes as probes of heart
excitability
ACRIDINES, AMINOACRIDINES
R01HL-08508-15 Cardiac conductivity and automaticity
(human, dogs, rabbits)
ACRIDINES, QUINACRINE
ROlHL-17702-04 Electro-optical dyes as probes of heart
excitability
ACROMEGALY
SEE PITUITARY GLAND DISORDERS, ACROMEGALY
ACRYLIC POLYMERS (RESINS)
SEE PUSTICS, ACRYLIC POLYMERS
ACTASCAN
SEE RADIOGRAPHY, SCANNING, CAT*
ACTH
SEE PITUITARY-DIENCEPHALON HORMONES, ACTH
ACTH INHIBITORS
SEE PITUITARY-DIENCEPHALON HORMONES, ACTH INHIBITORS
ACTIN
SEE MUSCLE PROTEINS (AND CONTRACTILE PROTEINS)
ACTIN
ALPHA-ACTININ
SEE MUSCLE PROTEINS (AND CONTRACTILE PROTEINS)
ALPHA-ACTININ
ACTINOMYCIN
SEE ANTIBIOTICS, ACTINOMYCIN
SEE ANTIBIOTICS, ACTINOMYCIN D
ACTINOZOA
SEE COELENTERATES, ANTHOZOA*
ACTION POTENTIALS
SEE ELECTROPOTENTIALS, ACTION POTENTIALS
ACTIVATION OF LYMPHOCYTES
SEE IMMUNITY, CELLUUR, LYMPHOCYTE ACTIVATION,
TRANSFORMATION AND PROLIFERATION
ACTIVATION PRODUCT
SEE BLOOD COAGULATION, ACTIVATION PRODUCT
ACTIVE IMMUNIZATION
SEE IMMUNITY, IMMUNIZATION ACTIVE
ACTIVE TRANSPORT
SEE BIOLOGICAL TRANSPORT, ACTIVE TRANSPORT
ACTOMYOSIN
SEE MUSCLE PROTEINS (AND CONTRACTILE PROTEINS)
ACTOMYOSIN
ACUTE DISEASES (DISORDERS)
SEE DISEASES, ACUTE (GENERAL)
ACUTE LEUKEMIA
SEE NEOPLASMS OF BLOOD AND RE SYSTEM, LEUKEMIA
ACUTE
ACUTE PHASE PROTEINS
SEE IMMUNOLOGY, ACUTE PHASE PROTEINS
ACUTE RENAL FAILURE (LOWER NEPHRON)
SEE KIDNEY DISORDERS, NEPHROSIS LOWER NEPHRON
ACUTE TREATMENT.DRUGS
SEE DOSAGE AND ROUTE, RATE AND DURATION OF
ADMINISTRATION
ACYLATION
SEE ACYLS, ACYLATION
ACYL-COA
SEE COENZYMES, COENZYME A, ACYL-COA
ACYl COENZYME A DEHYDROGENASES
SEE OXIDOREDUCTASES, ACYL-COA DEHYDROGENASE
ACYL-COENZYME A
SEE COENZYMES, COENZYME A. ACYL COA
ACYL GROUPS
SEE ACYLS, ACYL GROUPS
ACYLS, ACYL GROUPS
R01HL-15646-03 Lipid studies in vascular smooth muscle
cells (human, monkeys)
R01HL-20308-02 Regulation of myocardial acylcarnitine
transport (rats)
R23HL-21251-01 Metabolism of neutral lipids in the
pulmonary alveolus (rabbits)
ACYLS, ACYLATION
ROlHL-13567-06 Ion transport across cell membranes
(human)
ROlHL-18181-04 Surfactant metabolism-Alveolar cells and
lung disease (mice, rabbits)
ROlHL-22566-01 Mesoionic purinones as
phosphodiesterase inhibitors
POlHL-226 19-01 0007 Cellular mechanisms of heart
failure • Regulation of contractile protein levels in heart
muscle (rats)
ROlHL-22651-01 Control of protein metabolism in heart
muscle
ACYLS, ACYLATION, ACETYLATION
POlHL-12738-10 0001 Physiologicpharmacology and its
clinical applications - Clinical pharmacology of cardioactive
drugs (human)
P50HL-14147-08 0001 Specialized center of research in
thrombosis Role of aspirin, other anti-platelet agents in
platelet function (rat. human)
ROIHL 17947-04 Experimental renal and neurogenic
hypertension (human, animals)
ROIHL 20794-02 Prostaglandin synthesis in human
platelets (also in sheep, rabbit)
** ROlHL-20925-01 The acetylation of fetal hemoglobin
(human)
N-ACYLSPHINGOSINE
SEE SPHINGOUPIDS, CE.RAMIDE
ACYLTRANSFERASES
SEE TRANSACYLASES
ADAMS-STOKES SYNDROME
SEE HEART DISORDERS, ARRHYTHMIA, HEART BLOCK
STOKES-ADAMS SYNDROME
ADAPTATION BIOLOGICAL, PHYSIOLOGICAL
SEE ENVIRONMENT, ADAPTATION
ADAPTATION, PSYCHOLOGICAL
SEE PSYCHOLOGICAL ADAPTATION
ADDISON'S DISEASE
SEE ADRENAL GUNDS DISORDERS, ADDISON'S DISEASE
ADENINE
SEE PURINES, ADENINE
ADENINE NUCLEOSIDE
SEE PURINE NUCLEOSIDES, ADENINE NUCLEOSIDES
ADENINE NUCLEOTIDES
SEE PURINE NUCLEOTIDES, ADENINE NUCLEOTIDES
ADENINE PHOSPHORIBOSYLTRANSFERASE
SEE GLYCOSYLTRANSFERASES, ADENINE
PH OSPHORIBOSYLTRANSFERASE
ADENOMA
SEE NEOPLASMS, ADENOMA
ADENOSINE
SEE PURINE NUCLEOSIDES, ADENINE NUCLEOSIDES
ADENOSINE
ADENOSINE DEAMINASE
SEE AMINOHYDROLASES. ADENOSINE DEAMINASE
ADENOSINE DIPHOSPHATE
SEE PURINE NUCLEOTIDES, ADENINE NUCLEOTIDES, AOP
ADR
•Excludes routine methodology OR covers only general projects which preclude indexing
"Oneiited significantly to above subject.
at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
ADENOSINE MONOPHOSPHATE
SEE PURINE NUCLEOTIDES, ADENINE NUCLEOTIDES. AMP
ADENOSINE MONOPHOSPHATE CYCLIC
SEE PURINE NUCLEOTIDES, ADENINE NUCLEOTIDES AMP
CYCLIC
ADENOSINE PHOSPHATES
SEE PURINE NUCLEOTIDES, ADENINE NUCLEOTIDES
ADENOSINE PHOSPHATES
ADENOSINE TRIPHOSPHATASE
SEE PHOSPHATASES, ADENOSINE TRIPHOSPHATASE
ADENOSINE TRIPHOSPHATE
SEE PURINE NUCLEOTIDES, ADENINE NUCLEOTIDES, ATP
S-ADENOSYLMETHIONINE
SEE NUCLEOSIDYL AMINO ACIDS, S-ADENOSYLMETHIONINE
ADENOVIRUSES
SEE VIRUSES, ADENOVIRUSES
ADENYLATE CYCLASE
SEE NUCLEOTIDYL-CYCLASES. ADENYUTE CYCUSE
ADENYLATE DEAMINASE
SEE AMINOHYOROUSES, ADENYUTE DEAMINASE
ADENYLATE KINASE
SEE PHOSPHOTRANSFERASES, ATP:AMP
PHOSPHOTRANSFERASE
ADENYL-5-PHOSPHATASE
SEE PHOSPHOMONOESTERASES, 5 -NUCLEOTIDASE
ADH
SEE PITUITARY-DIENCEPHALON HORMONES, VASOPRESSIN
ADHESION
SEE PHYSICAL PROPERTIES, ADHESION
ADHESIONS (DISEASE COMPLICATIONS)
SEE DISEASES. COMPLICATIONS. ADHESIONS
ADHESIVES
SEE SURGICAL ADHESIVES
ADIPOKINETIC SUBSTANCES, PITUITARY
SEE LIPID MOBILIZING FACTORS PITUITARY
ADIPOSE TISSUE
SEE CONNECTIVE TISSUE. ADIPOSE
ADJUNCT HEALTH (CARE) PERSONNEL
SEE HEALTH SCIENCES PROFESSIONS. HEALTH (CARE)
PERSONNEL ALLIED
ADJUNCT MENTAL HEALTH PERSONNEL
SEE MENTAL HEALTH PERSONNEL ADJUNCT
ADJUSTMENT, EMOTIONAL
SEE PSYCHOLOGICAL ADAPTATION. EMOTIONAL ADJUSTMENT
ADJUSTMENT, SOCIAL
SEE PSYCHOLOGY SOCIAL. SOCIAL ADJUSTMENT
ADJUSTMENT TO ENVIRONMENT
SEE ENVIRONMENT. ADAPTATION
ADJUVANTS lAAMUNOLOGtC
SEE IMMUNOLOGICAL PREPARATIONS. ADJUVANTS
IMMUNOLOGIC
ADMINISTRATION
SEE HEALTH ADMINISTRATION
ADOLESCENCE
SEE CHILDREN. ADOLESCENCE (12 TO 21 YRS)
ADP
SEE PURINE NUCLEOTIDES. ADENINE NUCLEOTIDES. ADP
ADRENAL CIRCULATION
R01HL-21308-01 Prostaglandins and local control of the
circulation (rats, dogs)
ADRENAL CORTEX HORMONES
SEE ALSO GLOBULINS. CORTICOSTEROID BINDING GLOBULIN
ROlHL-05883-18 0001 Reflex control of resistance and
capacitance vessels - Naturally occurring vasoactive
substances and the vascular neuroeffectors (dog)
POlHL-06285-18 0209 Cardiovascular-respiratory
physiology and biochemistry - Metabolic studies of isolated
lung cells (human, animals)
POlHL-06370-17 0014 Cardiopulmonary and renal
pathology research center - Quantitative morphology in
cardiac disease (human, rats, dogs)
POlHL-06664-17 0010 Cardiopulmonary function in
remediable vascular disease - Ischemia and acute renal
failure (rats)
POlHL-11351-12 0015 Cellular and molecular
mechanisms of myocardial function - Effects of hypoxia
and ischemia on ion exchange and heart function (rabbits)
** POlHL-11414-11 0014 Thrombosis and atherosclerosis
program - Role of adrenal in human essential hypertension
P50HL 14218-07 0017 Pulmonary SCOR-Newborn lung
center - Transvascular fluid exchange, vasoactive mediators
in RDS (sheep, cat)
(contd)
\
i
ADR
ROIHI U854 07 lum tnd ti8»u» mechiniCJ (monkeys.
dofs)
PSOHl 15061 O; 0009 Response ol luni lo iniury
Alveolii miciophiies (human, tabbi(s)
ROIHI 1H16 07 lunj surticlanl system Contiol
mechinisms (lats)
POIHI 16137 05 0013 Alveolai biolojy Development and
patlioloiy ol surtactant foimation ol alveolar (tabbils.
sheep)
ROIHI 16611 04 Digitalis receptot ol the heart (guinea
pigs, lats)
ROIHL 16651 05 Evaluation ol steioid theiapy in
sarcoidosis (human)
ROIHL 1671003 Myocardial subcellular localization of
calcium (dogs)
ROIHL 17903 03 Regional circulatory responses to hypoxia
(rats. cats, rabbits)
ROIHL 1820* 03 Regional blood How in viral myocarditis
(turkeys)
POIHL 18208 04 0003 Center lor the study ol blood cell
rheology Bone marrow mrciocirculation (rats, mice)
• P50HL 18323 04 0037 SCOR hypertension center
Adrenocortrcal lactors in chrldhood hypertension
• P50HL 18323 04 0038 SCOR hypertension center •
Unknown adrenocortical mechanisms in hypertension
(human)
POIHL 18645 03 0003 Biology ol the artery wall and
atherosclerosis Synthesis of connective tissue proteins by
smooth muscle cells (human, monkeys)
ROIHL 1876203 Posttraumatic pulmonary insufliciency
(dogs)
P01HL1882702 0006 Platelet vessel wall interactrons in
thrombogenesis Platelet immune injury In man
'* ROIHL 18923-02 Steroid-induced hyperlipidemia and
hypertension (human, rats)
ROlHL-1901003 Metabolism and cell biology of lung
surtactant system (rabbits, sheep)
P50HL-19187-02 0001 Pediatric pulmonary SCOR-Hyaline
membrane disease Hyaline membrane disease -Changes
in lung mechanics and gas exchange (monkeys)
P50HL1918702 0002 Pediatric pulmonary SCOR-Hyaline
membrane disease - Hyaline membrane disease-Alterations
in surface active material (monkeys)
ROlHL-19237-03 Obstructive lung disease and alveolar
macrophages (human, animals)
** R01HL-1953903 Pathology of hypertensrve-associated
arteritis (rabbits)
R0IHL19669-03 Lung organ culture and surfactant
biosynthesis (adult and fetal rats)
** PO1HL1971702 0027 Response of the lung to in|ury -
Hormone control ol lung growth and development (rats)
POIHL-19717-02 0038 Response of the lung to injury •
Interstitial lung disease -Clinical, pathologic and
epidemiologic
P01HL1971702 0039 Response of the lung to injury -
Lung scanning in alveolitis and asbestolrc interstitial
pneumonia (human, animal)
P01HL-I971702 0040 Response of the lung to injury -
Immunosuppressive drugs in usual interstitial pneumonia
(human)
ROlHL-19722-03 Aerosol growth in the respiratory system
(models)
R01HL1978202 Pharmacologic studies on the ischemic
heart (dogs)
ROlHL-20080-02 Surgically induced myocardial edema
(dogs)
ROlHL-20384-09 Social stimulation. RNA and
cardiovascular disease (animals)
R01HL-2090502 Synthesis of fetal hemoglobin in erythroid
cells (sheep, human)
R01HL-21140-01 Studies of pulmonay alveolar
macrophage function (rabbits)
ROlHL-21418-02 Experimental myocardial infarction (rats)
ROlHL-21628-02 Biosynthesis of lung surfactant lipid
(rabbit)
*♦ R23HL-21917-01 Adrenal steroids in adolescent and adult
hypertension
ROlHL-2206501 Intractability, medication, and coping
styles in asthma (human)
ROIHL-2226601 Production of proteases by lung cells in
culture (human, rodents, rabbits, sheep)
ROlHL-22547-01 Behavioral treatment of Raynaud's
disease (human)
ROlHL-2256302 Prostaglandins, the kidney and
hypertension (rats)
ROlHL-2287301 Adrenoceptor interconversion and
hormone homeostasis
ROlHL-23981-01 Acute alveolar injury (dogs)
** NOIHR-62948-04 Evaluate antenatal steroid therapy in
neonatal respiratory distress syndrome
** NOlHR-62949-05 Evaluate antenatal steroid therapy in
neonatal respiratory distress syndrome
** NOlHR-62950-04 Evaluate antenatal steroid therapy in
neonatal respiratory distress syndrome
" NOlHR-6295104 Evaluate antenatal steroid therapy in
neonatal respiratory distress syndrome
** NOlHR-62952-05 Evaluate antenatal steroid therapy in
neonatal respiratory distress syndrome
ADRENAL CORTEX HORMONES, ALDOSTERONE
SEE ALSO ADRENAL CORTEX HORMONES. ALOOSTERONE
STIMULATING FACTORS
SEE AlSOAORLNAl CORKX HORMONIS 4 I'RK.NI Nt
IIBIIA 1H7I IRIOl 1,20 DIOm
SEE AISOADRfNAl GIANDS DISOHDI RS
HYIMRAIOOSIIRONISM
SEE AlSOAORfNAl CiANDS OlSOROfKS
HYPOAIDOSIIRONISM
ROIHL 00759 29 Regulation ol electrolyte and acid base
equilibrium (dogs)
ROIHI 02493 ?2 Kidney lunction in experimental heart
lailure (dogs, rats)
ROIHL 03303 21 factors regulating electrolyte excretion by
the kidney (human, dogs)
■• POIHL 06285 18 0193 Cardiovascular fespiralory
physiology and biochemistry Hormonal regulation ol
sodium transport Aldosterone (rats, toads)
'* POIHL 06285 18 0194 Cardiovascular respiratory
physiology and biochemistry Hormonal regulation ol
sodium transport RNA synthesis (rats, toads)
POIHL 06285 18 0196 Cardiovascular resprratory
physiology and biochemistry Hormonal regulation ol
sodium transport Epithelial cell membranes (toads)
P01HL06285 18 0199 Cardiovascular respiratory
physiology and biochemistry Renal tubular reabsorption ol
sodium chloride (hamsters, rabbits)
P01HL06664 17 0040 Cardiopulmonary functron in
remediable vascular drsease The coupling of ion transport
to metabolism (toads)
POIHL 0683517 0030 Cardiovascular disease Synthesrs
and pharmacology of angiotensin antagonists (rats, cats)
** POIHL 06835 17 0032 Cardiovascular disease • Synthesis
of angiotensin II as inhibitors lor aldosterone
POlHL-06835 17 0050 Cardiovascular disease 18
Hydroxylase block in the 17 alphahydroxylase deficiency
syndrome (human)
POlHL-0683517 0055 Cardiovascular disease Vascular
and adrenocortical response to angiotensin II (dogs)
** POlHL-0683517 0055 Cardiovascular disease -
Angiotensin analogs Sarcosine on arterial pressure,
aldosterone (dogs)
R01HL06975-18 Pathogenesis and preventron of
hypertension (rats)
ROlHL-0991112 Hormonal and dietary modification of
NaCl toxicity (rats) mice)
** R01HL09921 13 Mechanisms related to congestive heart
failure (dogs, human, rat)
M ROIHL 10612-13 Humoral lactors rn heart failure and
hypertension
ROlHL-10612-13 0018 Humoral factors in heart failure
and hypertension • The pathogenesis of experimental renal
hypertension (dogs, rabbits, rats)
** ROlHL-10612-13 0019 Humoral factors in heart failure
and hypertension - Pathogenesis of hypertension in the
spontaneous hypertensive rat
ROIHL 10612 13 0020 Humoral factors in heart failure
and hypertension The control of renin release in the dog
** ROlHL-10612-13 0021 Humoral factors in heart farlure
and hypertension - The control of aldosterone secretion
(dogs)
•• ROlHL-11046-12 Renin, angiotensin, steroids, ions and
blood pressure (human, sheep, rabbits)
POlHL-11414-11 0014 Thrombosis and atherosclerosis
program - Role of adrenal in human essential hypertension
M POlHL-1167811 Cardiovascular dynamics and their
control
P01HL11678-11 0034 Cardiovascular dynamics and their
control - Renal function curves in intact dogs
POIHL 11678-11 0040 Cardiovascular dynamics and their
control - Control of plasma potassium concentration (dogs)
** POlHL-11678-11 0046 Cardiovascular dynamics and their
control ■ Regulation of aldosterone secretion and related
factors (dogs)
" POlHL-11678-11 0047 Cardiovascular dynamics and their
control ■ Unidentified pituitary factor in regulation of
aldosterone secretion (rats)
POlHL-11678-11 0065 Cardiovascular dynamics and their
control Body fluid volumes in the genesis of hypertensron
Cogs) ^ .^ .
** POlHL-1 1678-11 0066 Cardiovascular dynamics and their
control - Closed-loop analysis of the aldosterone control
system (dogs)
** R01HL13917-20 Secretron and effects of adrenal
hormones (human, rabbits, sheep)
** ROlHL-14148-07 0007 The regional circulations ■ Salivary
composition in hypertension (human)
P50HL-1415908 0008 Specialized center of research in
hypertension - Renal function and sodium metabolism in
hypertension (rats, human, rabbits)
P50HL 14159-08 0020 Specialrzed center of research in
hypertension ■ Renin-mineralocorticoid system in
hypertension (human, rat, dog)
P50HL 1415908 0021 Specialized center of research in
hypertension - Genetic studies of the physiology of
hypertension (human, rats)
P50HL-14159-08 0022 Specialized center of research in
hypertension - Core laboratory
P50HL1419208 0003 Specialized center of research in
hypertension - Prostaglandins as mediators of renin
secretion (human, dog)
P50HL-14192-08 0007 Specialized center of research in
hypertension - Role of new mineralocorticoids in
hypertension (human, rats)
ADR
ROIHI 1 4 106 0/ Quanlilicalion ol artf rial pmiure control
(do|\)
POIHI 14388 0/ UIX8 R«|ul<lion ol the circulaliofl in
pathological \\t\*\ Renin in(ialen-.in jyilam in th» ihMp
lelu\
' POIHI 14388 0/ 0190 Regulation ol the circulation in
pathological states Mechanism-, ol the renal actiont of
aldosterone (rats)
POIHI 14388 0/ 0191 Regulation ol Ihe circulation in
pathological states Regulation ol chloride transport in
epithelial membranes (turtles)
POIHL 14388 07 0223 Regulation of Itie circulation in
pathological states Kallikrem kinin system in hypertension
(rats)
POIHL 14388 0/ 0274 Regulation ol the circulation in
pathological states Kallikrem kinin system in hypertension
(human)
POIHL 14388 0/ 9002 Regulation ol Ihe circulation in
pathological stales Core immunoassay laboratory (rabbrts)
ROIHL 1649604 Prostaglandins and renin experimenlal
hypertension (rabbits)
ROIHL 1665805 Intrarenal regulation ol sodium
reabsorption
ROIHL 1691805 Role of steroids in hypertension (human)
ROIHL 1736404 Big renin' Biochemical and clinical
studies (human)
ROIHL 1770504 Kallikrem kinin system in hypertension
(human, rats, dogs)
'• ROIHL 17847 04 Cardiovascular and renal lunctions ol
marmots
ROIHL 17958 04 Circulatory effects of operant
cardiovascular control (baboons)
P50HL 18318 03 0003 Pathogenesis and complications ol
hypertension Core biochemical laboratory
P50HL 1831803 0004 Pathogenesis and complications of
hypertension Sterord and renin profiles in hypertension
(rats, human)
P50HL 18318-03 0014 Pathogenesis and complications of
hypertension Arterial metabolism and atherogenesis (rat,
rabbit) ,
P50HL18318-03 0019 Pathogenesis and complications of
hypertension - Renin angiotensin system in blood pressure
regulation (human, rat, dog)
P50HL-18323-04 0011 SCOR hypertension center ■
Endocrine profiling on a selected normal population
(human)
P50HL18323-04 0012 SCOR hypertension center ■ Renin
as a risk factor (human)
*• P50HL-1832304 0033 SCOR hypertension center - Core
laboratory-Renin, aldosterone and bradykinin methodology
P50HL-18323-04 0038 SCOR hypertension center -
Unknown adrenocortical mechanisms in hypertension
(human)
** P50HL18323-04 0043 SCOR hypertension center -
Pharmacology -Renin-aldosterone mechanisms in essential
hypertension (human)
POIHL 18575-03 0002 Mechanisms of vascular changes
in hypertension Endocrines, electrolytes, and
hemodynamics in hypertension (pigs)
POlHL-18575-03 0011 Mechanisms of vascular changes
in hypertension ■ Chemistry laboratory core facility
ROlHL-18624-03 Study of kinins in hypertension and other
diseases (human)
ROlHL-18862-02 Thirst and its contribution to edema
(dogs)
** ROIHL-18882-02 Hormones in hypertension (human)
ROlHL-18891-02 Electrolyte intake and blood pressure in
hypertension (human)
ROlHL-18893-03 Mechanism of angiotensin action -Role of
receptor (rats)
** ROlHL-1927903 Intracellular action of aldosterone in
hypertension (human, rats)
ROlHL-19287-03 The antihypertensive function of the
renal medulla (human, rats, rabbits)
P50HL-19362-02 0010 A/S SCOR-Atherosclerosis in
nonhuman primates - Antihypertensive therapy-
Atherogenesis in experimental hypertension (baboon)
ROlHL-19428-03 Role of angiotensin sensitivity in renin
release (human)
ROlHL-19467-03 Regulation of blood pressure (rats, dogs)
ROlHL-1953903 Pathology of hypertensive-associated
arteritis (rabbits)
R01HL19644-03 Etiological factors in hypertension
(human, dogs, rats)
** ROlHL-20176-02 Biochemistry and genetics of salt
hypertension (rats)
** ROIHL 20201-01 Hypertension and vascular steroid
receptors (rats)
ROIHL 20572-02 0003 Hemodynamic relations to
metabolism in hypertension Cardiac output and organ
blood flow In hypertension (rats)
** R23HL-2106602 Angiotensin and prostaglandin control of
aldosterone (rats)
ROlHL-21092-02 Factors other than renin in renal
hypertension (rats)
'* ROlHL-21 112-02 Aldosterone binding, clearance, and
secretion in man
ROlHL-21435-02 Control, cardiovascular and renal effects
of potassium (dogs)
R23HL-21917-01 Adrenal steroids in adolescent and adult
hypertension
(contdl
•txcluoes routine methodology OR covers only general proiects which preclude indexing at Ihe specific level
•*Oriented significantly to above sut))ect
M Grant has subprojects describing specific research aspects.
See Appendix lor investigators name and grant number.
AOR
** ROlHL-21996-01 Alteration of digitalis and aldosterone
disposition (ratsr rabbits, mice, dogs)
ROlHL-22069-02 Experimental renal arterial tiyperlension
(dogs)
ROlHL-2229802 Origins of hypertension (human)
ROIHL-22617-01 Angiotensin, hypertension and the CNS
(sheep)
ROlHL-22990-01 Angiotensin II receptors-Mechanisms of
regulation (rats)
ROlHL-23115-01 Regulation of active sodium transport
(frogs, rats)
ROlHL-2320101 Mechanisms of hypertension (human
rats)
ROIHL-23602 01 Physiology of renin, aldosterone and
prostaglandin (human, rats, dogs)
ADRENAL CORTEX HORMONES, ALDOSTERONE
INHIBITORS
SEE ALSO STEROIDS SPIROUCTONES. SPIRONOUCTONE
POlHL-06835-17 0055 Cardiovascular disease ■ Vascular
and adrenocortical response to angiotensin II (dogs)
ADRENAL CORTEX HORMONES, ALDOSTERONE
STIMULATING FACTORS
SEE ALSO PEPTIDES. VASOACTIVE PEPTIDES ANGIOTENSIN II
SEE ALSO PITUITARY-DIENCEPHALON HORMONES ACTH
P50HL-18323-04 0044 SCOR hypertension center -
Angiotensin blockade to identify angiotensin II factor in
hypertension (human)
ADRENAL CORTEX HORMONES
CORTICOSTERONE
ROlHL-0697518 Pathogenesis and prevention of
hypertension (rats)
ROIHLI 1046-12 Renin, angiotensin, steroids ions and
blood pressure (human, sheep rabbits)
POlHL-1 1310-12 0063 Mechanisms of cardiovascular
disease - Myocardial function, metabolism and cellular
integrity after heart surgery (dogs)
ROlHL-17706-04 Psychosocial hypertension,
catecholamines and drugs (mice)
P50HL-1831803 0004 Pathogenesis and complications of
hypertension - Steroid and renin profiles in hypertension
(rats, human)
P50HL-I8323-04 0038 SCOR hypertension center -
Unknown adrenocortical mechanisms in hypertension
(human)
ROlHL-19644-03 Etiological factors in hypertension
(human, dogs, rats)
R23HL 2191701 Adrenal steroids in adolescent and adult
hypertension
ADRENAL CORTEX HORMONES, CORTISONE
POlHL-06370-17 0013 Cardiopulmonary and renal
pathology research center - Morphologic analysis of
vascular prosthesis (human, dogs)
ROlHL-12085-10 Lipoprotein-carbohydrate metabolism
(human, rats)
ROlHL-12766-09 Structure-function relation of blood
vessels (rats, monkeys)
POlHL-16769-05 0010 Pathobiologic and host defense
reactions m the lung - Bronchus associated lymphoid
tissue and delayed hypersensitivity (rabbits)
ROIHL 18028-03 Absorption of nonvolatile compounds
from the lung
POlHL-18576-03 0007 Thrombosis research program
project - Relationships between coagulability and
thrombosis (human, animals)
POlHL-19717-02 0007 Response of the lung to injury -
Cellular level studies of prostaglandin-like molecules
(cattle)
R23HL 21997-01 Pulmonary immunopathology in the
compromised host (guinea pigs)
ADRENAL CORTEX HORMONES
DEOXYCORTICOSTERONE
R01HL00759-29 Regulation of electrolyte and acid base
equilibrium (dogs)
R01HL-0991M2 Hormonal and dietary modification of
NaCl toxicity (rats) mice)
ROlHL-l 1046-12 Renm, angiotensin, steroids, ions and
blood pressure (human, sheep rabbits)
P50HL 14192-08 0007 Specialized center of research in
hypertension - Role of new mineralocorticoids in
hypertension (human, rats)
ROlHL-14560-07 Hypertension produced by sympathetic
dysfunction (human, rats)
ROIHL 16658-05 Intrarenal regulation of sodium
reabsorption
ROIHL-1691805 Role of steroids in hypertension (human)
ROIHL 17516-04 Role of androgen as a risk factor in
atherogenesis (human, animals)
P50HL-1831803 0003 Pathogenesis and complications of
hypertension - Core biochemical laboratory
P50HL 18318-03 0004 Pathogenesis and complications of
hypertension ■ Steroid and renin profiles in hypertension
(rats, human)
P50HL-18318-03 0009 Pathogenesis and complications of
hypertension - The mineralocorticoid-hypertensive syndrome
in man
P50HL 18323-04 0038 SCOR hypertension center -
Unknown adrenocortical mechanisms in hypertension
(human)
PC1HL18575-03 0002 Mechanisms of vascular changes
in hypertension ■ Endocrines, electrolytes, and
hemodynamics in hypertension (pigs)
POIHL 18575-03 0005 Mechanisms of vascular changes
in hypertension - Renin synthesis in normotensive and
hypertensive pigs (also rats, dogs)
POIHL 18575-03 0011 Mechanisms of vascular changes
in hypertension - Chemistry laboratory core facility
ROlHL-2017602 Biochemistry and genetics of salt
hypertension (rats)
ROlHL-2111202 Aldosterone binding, clearance, and
secretion in man
ADRENAL CORTEX HORMONES, ll-DEOXY-l?-
HYDROXYCORTICOSTERONE
POlHL-06835-17 0050 Cardiovascular disease - 18-
Hydroxylase block in the 17 alpha-hydroxylase deficiency
syndrome (human)
ROlHL-06975-18 Pathogenesis and prevention of
hypertension (rats)
P50HL-1832304 0038 SCOR hypertension center -
Unknown adrenocortical mechanisms in hypertension
(human)
R23HL-21917-01 Adrenal steroids in adolescent and adult
hypertension
ADRENAL CORTEX HORMONES,
GLUCOCORTICOIDS
POlHL-1034213 0027 The integrated function of
respiration and circulation - Control of respiration -
Cardiovascular adjustment to hypoxia and carbon monoxide
ROlHL-12990-09 Control of antidiuretic hormone secretion
and metabolism (dogs, rats, rabbits)
R01HL13595-08 Renin and vascular hyperreactivity in
hypertension (human, rats)
P50HL-14214-07 0023 Newborn lung center for hyaline
membrane disease - Regulation of fetal lung maturation -
Vitamin A (rat. rabbit, sheep, human)
P50HL-14214-07 0024 Newborn lung center for hyaline
membrane disease Synthesis and receptors for ACTH in
fetal lung (human)
R01HL15341-06 Lung hormonal and chromosomal
regulation (rats, rabbits)
ROlHL-16219-05 Mechanisms of atherogenesis in chronic
uremia (human, rats)
ROlHL-16918-05 Role of steroids in hypertension (human)
POIHL- 174 19-04 0006 Studies on mechanisms of
hemostasis - Effect of hormones, drugs and other agents
on fibrinogen synthesis (chick)
R01HL17458-04 Renal control of sodium excretion (rats)
ROlHL-1818104 Surfactant metabolism-Alveolar cells and
lung disease (mice, rabbits)
ROlHL-19072-03 Modification of tissue injury in
myocardial infarction (dogs, human)
R01HL-19n5-02 Hormonal control of tracheobronchial
cyclic AMP (rats, guinea pigs)
" P50HL-19185-02 0005 Pulmonary SCOR -Neonatal
respiratory distress syndromes - Role and mechanism of
glucocorticoids in fetal lung maturation (human rabbit)
P50HL.19I90-02 0003 Pulmonary SCOR -Pathophysiology
management of IRDS - Type II cells -Regulation and
differentiation (rat)
ROlHL-19195-03 Hormonal regulation of lung function
(rats)
ROlHL-19673-03 Surgical aspects of shock and hypoxia
(dogs, monkeys, rats)
ROlHL-2019902 Drug-induced alterations in infarct size
in the rat
ROlHL-20283-02 Maintenance of cellular integrity in
ischemic hearts (cats)
ROlHL-20371-02 Intravascular redistribution of blood
volume (dogs)
R23HL-22972 01 Microcirculatory function in hypotension
(rats, hamsters)
ROlHL-231 15-01 Regulation of active sodium transport
(frogs, rats)
ADRENAL CORTEX HORMONES,
HYDROCORTISONE
POlHL-0631417 0066 Immunologic mechanisms in
cardiovascular disease - Sensitization, cell-mediated
cytotoxicity, role of lymphocytes (human mice)
P0IHL06370-17 0004 Cardiopulmonary and renal
pathology research center - Lymphocytes in graft rejection
and immune surveillance (human)
ROlHL-12990-09 Control of antidiuretic hormone secretion
and metabolism (dogs. rats, rabbits)
ROIHL 14706-07 Fetal hearts in organ culture (mice)
R01HL15677-06 Autonomic nervous system function in
bronchial asthma (human, guinea pig, rabbit)
ROIHL 16364-04 Regulation of lipid biosynthesis and
transport (rats, swine, Xenopus)
ROlHL-17719-03 Lung iniury, substrate utilization oxygen
toxicity (rats, rabbits dogs)
P50HL-1832304 0038 SCOR hypertension center ■
Unknown adrenocortical mechanisms in hypertension
(human)
ROlHL-18537-04 Regional blood flow after acute
myocardial injury (dogs)
POIHL 18575-03 0001 Mechanisms of vascular changes
in hypertension - Arteries and resistance vessels in
hypertension (pigs, rats)
ADR
ROlHL-19115-02 Hormonal control of tracheobronchial
cyclic AMP (rats, guinea pigs)
P50HL-19185-02 0005 Pulmonary SCOR -Neonatal
respiratory distress syndromes - Role and mechanism of
glucocorticoids in fetal lung maturation (human rabbit)
ROlHL-19721-03 Lung inflammation -Lysosomal' proteases
and liposomes (human, rabbits)
" POlHL-19737-02 0003 Cellular and molecular aspects of
respiratory physiology - Cortisol-dependent alterations in
lung type II cells (rats)
ROlHL-19752-03 Phospholipid synthesis by fetal lung in
organ culture (rats)
ROlHL-20364-01 Episodic hypertension associated with
human behavior (air traffic controllers)
ROlHL-20719-02 Cold induced pulmonary hypertension
(cattle)
ROlHL-20783-02 Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
R23HL-21917-01 Adrenal steroids in adolescent and adult
hypertension
ADRENAL CORTEX HORMONES,
MINERALOCORTICOIDS
ROlHL-00759-29 Regulation of electrolyte and acid base
equilibrium (dogs)
ROlHL-06975-18 Pathogenesis and prevention of
hypertension (rats)
R01HL-0991M2 Hormonal and dietary modification of
NaCl toxicity (rats) mice)
ROIHL 11046-12 Renin, angiotensin, steroids. Ions and
blood pressure (human, sheep, rabbits)
POlHL-11414-11 0014 Thrombosis and atherosclerosis
program ■ Role of adrenal in human essential hypertension
ROlHL-14133-08 Intrarenal regulation of sodium
reabsorption (dogs, hamsters, rats)
** P50HL-14159-08 0020 Specialized center of research in
hypertension - Renin mineralocorticoid system in
hypertension (human, rat, dog)
" P50HL-14192-08 0007 Specialized center of research in
hypertension - Role of new mineralocorticoids in
hypertension (human, rats)
ROlHL-16658-05 Intrarenal regulation of sodium
reabsorption
R01HL16918-05 Role of steroids in hypertension (human)
R01HL1745804 Renal control of sodium excretion (rats)
ROlHL-1774903 Adrenocortical factors in human
hypertension (human)
R01HL18185-04 Cardiac glycosides and diuretics -Role of
NaO pump (dogs)
M P50HL-18318-03 Pathogenesis and complications of
hypertension
P50HL-1831803 0001 Pathogenesis and complications of
hypertension - Core clinical program
** P50HLI8318-03 0004 Pathogenesis and complications of
hypertension ■ Steroid and renin profiles in hypertension
(rats, human)
P50HL 1831803 0007 Pathogenesis and complications of
hypertension ■ Humoral factors and renal function in
experimental hypertension (rats)
" P50HL-1831803 0009 Pathogenesis and complications of
hypertension - The mineralocorticoid-hypertensive syndrome
in man
" P50HL18318-03 0010 Pathogenesis and complications of
hypertension - Hemodynamics in mineralocorticoid and low
renirr hypertension (human)
P50HL-18318-03 0011 Pathogenesis and complications of
hypertension - Adrenergic function -Renin and
mineralocorticoid activity (human)
P50HL-18323-04 0037 SCOR hypertension center -
Adrenocortical factors in childhood hypertension
P50HL-18323-04 0038 SCOR hypertension center ■
Unknown adrenocortical mechanisms in hypertension
(human)
POIHL-18575-03 0002 Mechanisms of vascular changes
in hypertension Endocrines, electrolytes, and
hemodynamics in hypertension (pigs)
ROlHL-18579-03 Vasoactive hormones and blood pressure
regulation (dogs. rats, rabbits)
ROIHL-18730-03 Role of mineralocorticoids in low renin
hypertension (human, rats)
** R01HL19279-03 Intracellular action of aldosterone in
hypertension (human, rats)
R01HL19644-03 Etiological factors in hypertension
(human, dogs, rats)
ROlHL-20201-01 Hypertension and vascular steroid
receptors (rats)
ROlHL-21 112-02 Aldosterone binding, clearance, and
secretion in man
ROlHL-21272-02 Sodium homeostasis and renal
prostaglandins (dogs)
R23HL-21291-02 Renin-mineralocorticoid axis in
hypertensive diabetics (human)
ROlHL-2177901 Steroids in adrenal regeneration
hypertension (rats)
ROlHL-22617-01 Angiotensin, hypertension and the CNS
(sheep)
ADRENAL CORTEX HORMONES, 4-PREGNENE-
1 1 BETA,I8,21-TRIOL-3,20-DIONE
SEE ALSO ADRENAL CORTEX HORMONES ALDOSTERONE
P50HL-18323-04 0038 SCOR hypertension center -
Unknown adrenocortical mechanisms in hypertension
(human)
I
i
;Excludes toutme metliodology OR covers only general proiects which preclude indexmi.
Unented significantly lo above sub|ccl
at the specific level.
M Grant has subproiects describing specific research aspects.
See Appendix for investigators name and grant number.
(contd)
ADR
KOIHl .'01 /B O:' Biochemistry and |«n«tics ol s«ll
hypotension (lats)
ADRENAL CORTEX HORMONES ANALOGS,
DEXAMETHASONE
COim iii.m'> 1 ' OOM) Cjidiovascular disease 18
Hviliinyi.iM' bio. k in tite \l liphi hydtoiylase deficiency
sylulliHlU' (tuim.nll
(?01HL llU4b I.' Kenin. «n|iotensin, steroids, ions and
blood pressure (human, sheep, rabbits)
POIHI 11414 11 0014 Thrombosis and atherosclerosis
program Role ol adrenal in human essential hypertension
ROIHI 1643/ Ob Diui! treatment ol atherosclerosis
(rabbits, monkeys)
ROIHL 17458 04 Renal control ol sodium excretion (rals)
ROIHI 17705 04 Kallikrein kinin system in hypertension
(human, rats, dogs)
ROIHL 1774903 Adrenocortical factors in human
hyparlension (human)
P50HL 18323 04 0037 SCOR hypertension center
Adrenocortical factors in childhood hypertension
ROIHI 1873003 Role of mineralocorticoids in low renin
hypertension (human, rats)
ROIHL 18923 02 Steroid induced hyperlipidemia and
hypertension (human, rats)
ROIHL 1923703 Obstructive lung disease and alveolar
macrophages (human, animals)
ADRENAL CORTEX HORMONES ANALOGS,
FLUDROCORTISONE
P01HL14388 07 0229 Regulation ol the circulation in
pathological states Mechanism ol postural hypotension
(human)
ADRENAL CORTEX HORMONES ANALOGS,
METHYLPREDNISOLONE
POlHL-06312 17 0018 Surgical cardiology - Cardiac
transplantation growth (calves)
R01HL08696 15 0012 Orthotopic heart transplantation -
Transplantation immunology -Modulation of donor
antigenicity (dogs)
R01HL0869615 0013 Orthotopic heart transplantation ■
Transplantation immunology -Cardiac heterotransplantation
(rabbits, dogs)
POIHL 13108-09 0001 Clinical heart transplantation -
Therapy and prognosis (human)
ROlHL-17479-04 Blood storage -The production of
cardiotoxic material (dogs, human, swine)
R01HL1892302 Steroid induced hyperlipidemia and
hypertension (human, rats)
R01HL19072-03 Modification of tissue injury In
myocardial infarction (dogs, human)
P50HL1915302 0003 SCOR -Pulmonary edemas-Eitology.
pathogenesis - Possible inhibitors of mediator release and
pulmonary vascular response (sheep)
R01HL-21G8402 0002 Radionuclide infarct sizing and
therapy evaluation - Evaluating myocardial imaging agents
in global and regional ischemia (rabbits)
R23HL-2289501 Smoke Inhalation -Biochemical and
cellular responses (rabbits, bacteria)
ADRENAL CORTEX HORMONES ANALOGS,
PREDNISONE
POlHL-13108-09 0014 Clinical heart transplantation
Platelets and coagulation In accelerated graft coronary
atherosclerosis
POlHL-17813-04 0001 Lung disease and the oxygenation
of blood and tissue - Diffuse interstitial lung disease-
Pathophysiology (human, dogs)
ROlHL-18923-02 Steraid-induced hyperlipidemia and
hypertension (human, rats)
ADRENAL CORTEX (HORMONES) INHIBITORS
SEE ALSO ADRENAL CORTEX HORMONES. ALDOSTERONE
INHIBITORS
POlHL-11414-11 0014 Thrombosis and atherosclerosis
program - Role of adrenal in human essential hypertension
ROlHL-19209-03 Role of ADH in experimental renal
hypertension (dogs, rats)
ADRENAL GLANDS
SEE ALSO ADRENAL MEDULU
SEE ALSO PITUITARY-ADRENAL AXIS
ROlHL-02033-23 Regulation of cholesterol esters In blood
and tissues (rat. cattle, human)
ROlHL-02363-20 Kinetics of water and electrolytes in
shock (dogs, rats)
POlHL-06835-17 0055 Cardiovascular disease - Vascular
and adrenocortical response to angiotensin II (dogs)
POlHL-06835-17 0056 Cardiovascular disease -
Angiotensin analogs -Sarcosine on arterial pressure,
aldosterone (dogs)
ROlHL-09921-13 Mechanisms related to congestive heart
failure (dogs, human, rat)
ROlHL-10942-09 Study of genetic hypertension in rats
ROlHL-12677-10 Surgical physiologic studies of Isolated
kidneys (dogs, rats)
ROlHL-17847-04 Cardiovascular and renal functions of
marmots
** P01HL-18974-03 0010 Experimental neurogenic
hypertension program - Biochemistry and regulation of
PNMT In brain (rats)
ROlHL-20061-02 Serum lipoproteins and cell cholesterol
metabolism (rats, human)
•• ('01 HI 20948 02 000? Molecular basis ol cholesterol
metabolism 101 pathwiiy in cell lines wilfi intormalive
properties other Ih.in fibiobl.nls
•* ROIHI 22990 01 AngiulrnMn II receptors Mechanisms ol
reguliilion (rats)
ADRENAL GLANDS DISORDERS
Sll AlSOUIStASfS SIGNS SYMi'IOMS, HIRSUIISM
SEi AlSOMtlAHOlIC DISORD! RS INBORN. IIPID (NfUTRAl)
STORACf WOl MAN'S DISEASE
SEE Also NfOPlASMS Of [NDOCRINfS ADRENAl GUNDS
NEOPLASMS
*• POIHI 06370 17 0015 Cardiopulmonary and renal
pathology research center Pathogenesis of chemically
induced tissue iniury (rats)
•• POlHt 06835 17 0050 Cardiovascular disease 18
Hydroxylase block in the 17 alpha hydroxylase deficiency
syndrome (human)
ROIHL 21272 02 Sodium homeostasis and renal
prostaglandins (dogs)
ROIHL 22506 01 Hemodynamics of the clinical
hypertensions
ADRENAL GLANDS DISORDERS, ADDISON'S
DISEASE
ROIHL 11046 12 Renin, angiotensin, steroids, ions and
blood pressure (human, sheep, rabbits)
ADRENAL GLANDS DISORDERS, ADRENAl
HYPERTENSION
SEE ALSO ADRENAL GLANDS DISORDERS.
HYPERALDOSTERONISM
SEE ALSO KIDNEY CIRCULATORY DISORDERS, RENAL
HYPERTENSION
SEE ALSO KIDNEY CIRCUUTORY DISORDERS, RENOPRIVAL
HYPERTENSION
** POlHL-06835-17 0047 Cardiovascular disease ■
Spironolactone in primary aldosteroidism (human)
POlHL-06835-17 0048 Cardiovascular disease -
Aldosterone producing adenoma prediction of curability
(human)
** ROlHL-06975-18 Pathogenesis and prevention of
hypertension (rats)
** ROlHL-09911-12 Hormonal and dietary modification of
NaCl toxicity (rats) mice)
ROlHL-10942-09 Study of genetic hypertension in rats
** ROlHL-11046 12 Renin, angiotensin, steroids, ions and
blood pressure (human, sheep, rabbits)
POIHL-11414-11 0014 Thrombosis and atherosclerosis
program - Role of adrenal in human essential hypertension
ROlHL-13408-05 Enviranmental-genetic Interactions in
hypertension (rats)
ROlHL-13917-20 Secretion and effects of adrenal
hormones (human, rabbits, sheep)
*" ROlHL-13936-06 Microvascular responses in hypertension
(human, rats)
P50HL-14159-08 0020 Specialized center of research in
hypertension - Renin-mineralocorticoid system in
hypertension (human, rat, dog)
P50HL-14159-08 0021 Specialized center of research in
hypertension - Genetic studies of the physiology of
hypertension (human, rats)
P50HL-14159-08 0024 Specialized center of research in
hypertension - Core resources (clinical, animal models)
** P50HL-14192-08 0007 Specialized center of research in
hypertension - Role of new mineralocorticoids In
hypertension (human, rats)
ROlHL-15839-05 Physiological role of isorenin and
kallikrein (animals)
•* ROlHL-17458-04 Renal control of sodium excretion (rats)
ROlHL-17749-03 Adrenocortical factors in human
hypertension (human)
" ROlHL-18102-02 Role of the adrenal cortex in human
hypertension
P50HL-183 18-03 0002 Pathogenesis and complications of
hypertension ■ Core experimental animal facility (rats,
rabbits)
** P50HL-18318-03 0004 Pathogenesis and complications of
hypertension - Steroid and renin profiles in hypertension
(rats, human)
P50HL-18318-03 0007 Pathogenesis and complications of
hypertension - Humoral factors and renal function in
experimental hypertension (rats)
M P50HL-18323-04 SCOR hypertension center
*• P50HL-18323-04 0037 SCOR hypertension center -
Adrenocortical factors in childhood hypertension
** P50HL-1832304 0038 SCOR hypertension center -
Unknown adrenocortical mechanisms in hypertension
(human)
P50HL-18323-04 0044 SCOR hypertension center -
Angiotensin blockade to Identify angiotensin II factor in
hypertension (human)
** POlHL-18575-03 0002 Mechanisms of vascular changes
in hypertension - Endocrines, electrolytes, and
hemodynamics in hypertension (pigs)
** POlHL-18575-03 0010 Mechanisms of vascular changes
in hypertension - Hypertensive pig Core
** ROlHL-18579-03 Vasoactive hormones and blood pressure
regulation (dogs, rats, rabbits)
" ROIHL 18893-03 Mechanism of angiotensin action -Role of
receptor (rats)
*• ROIHL 19027-03 Calcium and cyclic AMP in causation of
hypertension (rats)
AUK
•• ROIHI 14144 0) Conlrictplivt Ittroidl ind tipjrrrrnntal
hypertenMun (rati)
*• ROIHI 19209 01 Role ol AOH in txptrimtntil rtnd
hyperteuMon (dugs, rati)
NOIHI 19174 03 Pharmacology of kinini in citdioviKUlir
disease (rat',. rabbil%)
•■ ROIHI 19644 03 tliologir.al laclor-. in hypertension
(human dog-, rals)
ROIHL 201/6 02 Biochemistry and genetics ol •,all
hypertension (rals)
•* ROIHI 20201 01 Hypertension and vascular steroid
receptors (rals)
•• ROIHI 20384 09 Social stimulation, RNA and
cardiovascular disease (animals)
** ROIHI 20604 03 Sympathectomy Cardiovajcular and
molecular pharmacology (animals)
ROIHI 2130/ 01 Risk reduction and exercise fitnesj in a
population
" ROIHL 21498 02 Pathophysiology of edema (rats, calj)
•* ROIHL 21//9 01 Steroids in adrenal regeneration
hypertension (rats)
** ROIHL 2187701 Iso renins In the hypertensive rat
*" R23HL 21914 01 Studies of vasomotor control (rats)
ADRENAL GLANDS DISORDERS,
HYPERADRENALISM, CUSHING'S SYNDROME
POIHL 11414 11 0014 Thrombosis and atherosclerosis
program Role of adrenal in human essential hypertension
ROIHL 13595-08 Renin and vascular hyper reactivity in
hypertension (human, rats)
ADRENAL GLANDS DISORDERS,
HYPERALDOSTERONISM
SEE ALSO ADRENAL CORTEX HORMONES. ALDOSTERONE
SEE ALSO CARDIOVASCULAR DISORDERS. HYPERTENSION
(SYSTEMIC). ANGIOTENSIN RENIN ALDOSTERONE-
ASSOCIATEO
POlHL-06835 17 0045 Cardiovascular disease Pressure
volume-renin relationship In human hypertension
*♦ P01HL06835 17 0047 Cardiovascular disease -
Spironolactone in primary aldosteroidism (human)
POIHL 06835-17 0059 Cardiovascular disease
Metyrapone-induced hypertension in dog
ROIHL 10612-13 0018 Humoral factors in heart failure
and hypertension - The pathogenesis of experimental renal
hypertension (dogs, rabbits, rats)
** ROlHL-10914-10 Renal sodium transport in experimental
aldosteronism (dogs)
** ROlHL-11046 12 Renin, angiotensin, steroids, ions and
blood pressure (human, sheep, rabbits)
POIHL 11414 11 0014 Thrombosis and atherosclerosis
program - Role of adrenal in human essential hypertension
ROIHL-13595-08 Renin and vascular hyper- reactivity in
hypertension (human, rats)
ROIHL 13917-20 Secretion and effects of adrenal
hormones (human, rabbits, sheep)
P50HL-14159-08 0020 Specialized center of researoh in
hypertension - Renin mineralocorticoid system In
hypertension (human, rat. dog)
P50HL-14159-08 0021 Specialized center of researoh in
hypertension - Genetic studies of the physiology of
hypertension (human, rats)
P50HL-14159 08 0024 Specialized center of research in
hypertension - Core resources (clinical, animal models)
ROIHL-16918-05 Role of steroids in hypertension (human)
ROlHL-17458-04 Renal control of sodium excretion (rats)
ROlHL-17705-04 Kallikrein-kinin system in hypertension
(human, rats, dogs)
ROlHL-1774903 Adrenocortical factors in human
hypertension (human)
P50HL-I83 18-03 0009 Pathogenesis and complications of
hypertension - The mineralocorticoid-hypertensivc syndrome
in man
*• P50HL 18318-03 0010 Pathogenesis and complications of
hypertension - Hemodynamics in mineralocorticoid and low
renin hypertension (human)
P50HL-1832304 0042 SCOR hypertension center - Blood
viscosity and blood volume In hypertensive disease
(human, dog)
P50HL-I8323-04 0044 SCOR hypertension center -
Angiotensin blockade to identify angiotensin II factor in
hypertension (human)
ROlHL-18624-03 Study of kinins In hypertension and other
diseases (human)
R23HL-21066-02 Angiotensin and prostaglandin control of
aldosterone (rats)
ROIHL-21274-01 Prorenin-Physiological and biochemical
analysis (human)
ROlHL-21525-02 Effect of cations, anions and water upon
blood vessels (dogs, rats)
R0IHL-232O1-0I Mechanisms of hypertension (human,
rats)
ADRENAL GLANDS DISORDERS,
HYPOALDOSTERONISM
SEE ALSO METABOLIC DISORDERS INBORN, BARHER'S
SYNDROME
*' POlHL-06835-17 0049 Cardiovascular disease Selective
hypoaldosteronism (human)
(contd)
•Excludes routine mctliodology OR covers only general projects which preclude indexing at the specific level
"Oriented significantly to above subject
M Grant has subproiects describing specific research aspects
See Appendix for investigator s name and grant number
ADR
ADRENAL GUNOS DISORDERS,
HYPOAIDOSTERONISM, HYPORENINEMIC
POlHL-0683517 0059 Cardiovascular disease -
Metyrapone-induced hypertension in dog
ROlHL-1104612 Renin, angiotensin, steroids, ions and
blood pressure (human, sheep, rabbits)
ROIHLI 736404 'Big renin' -Biochemical and clinical
studies (human)
ADRENAL GLANDS NEOPLASMS
SEE NEOPUSMS OF ENOOCRINES. ADRENAL GUNOS
NEOPLASMS
ADRENAL HYPERTENSION
SEE ADRENAL GUNDS DISORDERS. ADRENAL HYPERTENSION
ADRENAL MEDULU
R01HL13666-06 Pharmacology of genesis of cardiac
rhythmicity (rats, cats)
ROlHL-18148-04 Adrenal catecholamine secretion
ROlHL-18995-04 Cardiovascular determinants of
catecholamine release (dogs)
ROlHL-2167001 Antiarrhythmic studies on 2-subsfituted
aminoindenes (dogs)
ROlHL-2217001 Factors influencing transmission at
adrenergic synpases
ADRENAL MEDULLA HORMONES
SEE ALSO PHENYULKYLAMINES, CATECHOUMINES
EPINEPHRINE
SEE ALSO PHENYULKYUMINES. CATECHOUMINES
NOREPINEPHRINE
R01HL1860101 Regulation of neurotransmitter release bv
adenosine (rats)
ADRENALECTOMY
POlHL-06835-17 0031 Cardiovascular disease - Synthesis
of potent antagonist of pressor action of angiotensin II
(animals)
POlHL-06835-17 0047 Cardiovascular disease ■
Spironolactone in primary aldosteroidism (human)
ADRENALIN OXIDASE
SEE OXIDOREDUCTASES. AMINE OXIDASE (FUVIN
CONTAINING)
ADRENALINE
SEE PHENYULKYUMINES, CATECHOUMINES, EPINEPHRINE
ADRENERGIC AGENTS
SEE NEUROPHARMACOLOGICAL AGENTS, SYMPATHOMIMETIC
ADRENERGIC BLOCKING AGENTS
SEE NEUROPHARMACOLOGICAL AGENTS. SYMPATHOLYTIC
ADRENERGIC ALPHA RECEPTOR AGENTS
SEE NEUROPHARMACOLOGICAL AGENTS. SYMPATHOMIMETIC
ADRENERGIC ALPHA
ADRENERGIC BETA RECEPTOR AGENTS
SEE NEUROPHARMACOLOGICAL AGENTS, SYMPATHOMIMETIC
ADRENERGIC BETA
ADRENERGIC ALPHA RECEPTOR BLOCKING
AGENTS
SEE NEUROPHARMACOLOGICAL AGENTS, SYMPATHOLYTIC
ADRENERGIC ALPHA
ADRENERGIC BETA RECEPTOR BLOCKING
AGENTS
SEE NEUROPHARMACOLOGICAL AGENTS, SYMPATHOLYTIC
ADRENERGIC BETA
ADRENERGIC RECEPTORS
SEE NEUROTRANSMITTERS RECEPTORS ADRENERGIC
RECEPTORS
ADRENERGIC ALPHA RECEPTORS
SEE NEUROTRANSMinERS RECEPTORS ADRENERGIC
RECEPTORS, ALPHA RECEPTORS
ADRENERGIC BETA RECEPTORS
SEE NEUROTRANSMinERS RECEPTORS ADRENERGIC
RECEPTORS. BETA RECEPTORS
ADRENOCORTICOTROPIC HORMONE
SEE PITUITARYDIENCEPHALON HORMONES. ACTH
ADRIAMYCIN
SEE ANTIBIOTICS, ADRIAMYCIN
ADSORPTION
SEE PHYSICAL PROPERTIES, ADSORPTION
ADULT ANIMAL
SEE AGE (ANIMAL), MATURE (ADULT)
ADULTS
SEE AGE (HUMAN), ADULT
AEROBES, BACTERIAL
SEE MICROORGANISMS, AEROBES
AEROBIC MICROORGANISMS
SEE MICROORGANISMS. AEROBES
AEROBIOSIS
SEE RESPIRATION INTERNAL, AEROBIOSIS
••nnpSf.Vc"""f "'".'?''?<"<'« O" "«'5 ""I* general proiecis which preclude indexing
Oriented signihcantly to above sub/eel.
AEROSOL AND PARTICLE BEAMS
SEE PHYSICAL PROPERTIES, AEROSOL AND PARTICLE BEAMS
AEROSOL THERAPY, RESPIRATORY DISORDERS
SEE RESPIRATORY ASSIST AND OXYGEN ADMINISTRATION
AEROSOL THERAPY
AEROSOLS
SEE PHYSICAL PROPERTIES. AEROSOLS
AFFECT
SEE PSYCHOLOGY. EMOTIONS
AFFECTIVE DISORDERS
SEE PSYCHOLOGY ABNORMAL. EMOTIONAL DISORDERS
AFFERENT NERVES
SEE NERVOUS SYSTEM, AFFERENT NERVES
AFFINITY CHROMATOGRAPHY
SEE PHYSICAL SEPARATION, CHROMATOGRAPHY. AFFINITY
AFIBRINOGENEMIA
SEE BLOOD COAGUUTION DISORDERS, AFIBRINOGENEMIA
AFRICA
SEE GEOGRAPHICAL SITES, AFRICA
AFRO AMERICANS
SEE SOCIAL GROUPS, ETHNIC, AMERICANS BUCK
AMERICANS
AFTER CARE (POST-HOSPITALIZATION)
SEE HEALTH CARE SERVICES, PATIENT CARE POST-
HOSPITALIZATION CARE
AGE (ANIMAL)
ROlHL-08359-14 Morphopharmacology of vascular
adrenergic transmission (rabbits rats)
POlHL-0880515 0039 Regulation of ventilation and
pulmonary circulation Carotid body (cats)
ROlHL-09234-13 Amino acids of contractile proteins of
failing hearts (dogs, hamsters)
ROlHL-1061213 0019 Humoral factors in heart failure
and hypertension - Pathogenesis of hypertension in the
spontaneous hypertensive rat
POIHL 1 131012 0089 Mechanisms of cardiovascular
disease ■ Structure and function in myocardial contraction
(dogs)
P01HL1131012 0106 Mechanisms of cardiovascular
disease Biochemical characterization of the collagens in
vascular tissue (catte)
POlHL-1237310 0005 Cardiopulmonary physiology and
pathophysiology ■ Characterization of fetal and neonatal
myocardium (human, cats)
POlHL-12738-10 0108 Physiologic pharmacology and its
clinical applications ■ Developmental electrophysiology and
pharmacology (human, animals)
P01HL12738-10 0134 Physiologic pharmacology and its
clinical applications ■ Adenylate cyclase and cAMP
phosphodiesterase in cardiac development (dogs)
POlHL-1438807 0168 Regulation of the circulation in
pathological states - Ionic basis of depolarization (rats
tissue culture)
R01HL1452607 Oral contraceptives and hypertension
(rats)
ROlHL-1544406 Neonatal development of adrenergic
receptor mechanisms (pigs)
R01HL-I5837-06 Renin and cardiac hypertrophy in
hypertension (rats)
R01HL15840-02 Sugar-induced heart lesions and vitamin
K deficiency (birds, mammals subhuman)
ROlHL-16420-02 Effect of training-detraining on the rat
heart
ROlHL-16454-03 Vascular muscle reactivity in
hypertension (human, rats)
POlHL-16748-05 0004 Cellular and immunological basis
of pulmonary diseases ■ Cellular and immunological
processes in pulmonary defense systems
ROlHL-17322-04 Functional characteristics of smooth
muscle isolated from lung (animals)
R01HL-I7768-04 Development of collateral ventilation
(dogs, fish, horses)
ROlHL-17776-04 Pulmonary mucus transport in
obstructive lung diseases (human)
ROIHL-1800203 Circulatory shock, trauma and RE-system
function (rats)
ROlHL-19056-03 Blood triglycerides and lipoprotein lipase
in the lung (rats)
ROlHL-19225-02 0002 Types and mechanims of
pulmonary hypertension - Effect of aorto-pulmonary shunt
(pigs)
ROIHL 19741-03 Murine CRD--A model of chronic
pulmonary inflammation (mice, rats)
R01HL-20170-02 Pulmonary infection in splenectomized
animals (mice)
POlHL-20552-02 0002 The development and regression of
cardiac hypertrophy Effect of treatment on the
hypertrophied left ventricle (rats)
ROlHL-20572-02 0007 Hemodynamic relations to
metabolism in hypertension - Drug effects on cardiac
function and hypertropy (rats)
POlHL-20581-01 0002 Vascular neuroeffector
mechanisms in health and disease - Trophic interaction
between adrenergic nerves and vascular smooth muscle
at the specific level
M Grant has subprojects describing specific research aspects
Sec Appendix for investigator's name and grant number
AGE
POlHL-20581-01 0005 Vascular neuroeffector
mechanisms in health and disease ■ Changes in the
neuroeffector mechanism in hypertension (rabbits)
POl HL-20581-01 0006 Vascular neuroeffector
mechanisms in health and disease - Neuroeffector
Pom^lTo^no^a^^"' '"."/''"' '" hypertension (human)
POlHL-20592-02 0010 Cell biology of cardiac and
skeletal muscle ■ Mitochondrial genesis during myocardial
cell hypertrophy and hyperplasia (rats)
ROlHL-20749-01 Developing heart -Biophysical aspects
(sheep) "^
ROlHL-21099-02 Subcellular changes of blood vessels in
hypertension (rats)
ROlHL-21245-02 Influence of chronic exercise on
hypertension (rats, primates)
ROlHL-21632-02 Development of a transcutaneous power
transfer system (cattle)
ROlHL-22226-01 Autonomic nervous elements in the
developing heart (rabbits)
ROlHL-22924-01 The airway mucosal barrier (guinea pigs)
ROIHL 23025-01 Adaptive heart growth in neonates and
adults (rats)
ROlHL-23980-01 Effects of digoxin therapy in newborn
and adult sheep
AGE (ANIMAL), IMMATURE
POlHL-14388-07 0193 Regulation of the circulation in
pathological states Ontogenesis of central nervous system
amines in hypertension (rats)
ROlHL-18082-03 Erythrocyte phosphates and vertebrate
gas transport (amphibians, reptiles)
R23HL 22309-01 Cardiovascular pharmacodynamics in
immature dogs
AGE (ANIMAL), lAAMATURE, LARVA
POlHL-07896-15 0060 Environmental biomedical research
program - Effect of pressure on development of marine
crustacean larvae
AGE (ANIMAL), INFANTS
POlHL-06312-17 0018 Surgical cardiology - Cardiac
transplantation growth (calves)
POlHL-11307-12 0002 Biophysical studies In pediatric
cardiology Cardiac extracellular electrophysiology (human,
dog, chimpanzee)
ROIHL 12827-08 Regulation of sodium excretion (dogs
rats)
POl HL-13480-09 0026 Cardiac electrophysiology - Neural
influences on cardiac electrophysiology and contraction
(dog, cat)
ROlHL-13666-06 Pharmacology of genesis of cardiac
rhythmicity (rats, cats)
P50HL-14164-07 0041 A/S SCOR-Comparative and
experimental atherosclerosis - Nonhuman primate pediatric
atherosclerosis risk factor
ROlHL-15797-05 Lipid metabolism and atherosclerosis in
primates (monkeys, human squirrels)
" R01HL-16292-05 0019 Surgeiy and non-obstructive
coronary insufficiency - Distortion of subendocardial vessels
in infant hearts (dogs)
R01HL-190I0-03 Metabolism and cell biology of lung
surfactant system (rabbits sheep)
" P50HL-19362-02 0001 A/S SCOR -Atherosclerosis in
nonhuman primates - Effects of infant nutrition on
atherosclerosis (baboons)
** P50HL-19362-02 0002 A/S SCOR-Atherosclerosis in
nonhuman primates ■ Infant caloric intake, adipose tissue
development and atherosclerosis (baboon)
ROlHL-19779-03 Biochemical basis of oxygen damage to
lung cells (guinea pigs, rats)
ROIHL-20548-02 Innervation of the lung (rats, monkeys)
ROlHL-21872-01 Myocardial perfusion In the hypertrophied
heart (dogs)
R01HL-23601-01 Early hypoxia and development of
respiratory control
AGE (ANIMAL), INFANTS, BIRTH WEIGHT
SEE ALSO AGE (ANIMAL), INFANTS PREMATURE AND LOW
BIRTH WfEIGHT
ROlHL-19352-03 Respiratory heat and water loss in
neonates
AGE (ANIMAL), INFANTS MORTAUTY
ROlHL-19651-03 Host factors in pathogenesis of
respiratory disease (human, hamsters)
AGE (ANIMAL), INFANTS NEWBORN
N01HB-4297M2 Chimpanzees for hepatitis research
ROlHL-01755-25 Fetal and neonatal cardiovascular
function (sheep)
ROlHL-02888-22 Interrelationships of circulation and
respiration (opossum cats)
** POl HL-06285-18 0125 Cardiovascular-respiratory
physiology and biochemistry - Myocardial function in the
fetal and neonatal lamb
" POlHL-06285-18 0129 Cardiovascular-respiratory
physiology and biochemistiy - Pulmonary microcirculation in
the fetus and neonate (lambs)
ROlHL-08659-14 Myocardial performance and metabolism
in the newborn (sheep)
POlHL-10436-13 0015 A multidisciplinary study of
congenital heart disease ■ Fetal and neonatal
cardiovascular physiology (sheep)
ROIHL-10942-09 Study of genetic hypertension in rats
(conid)
AOE
POIHI 11310 12 0064 M»ch«nijmj ol c«idiov«itul»i
diMisf lititcoditc tnatomical collection ol
tiinsposition of |i«<l titeiKs (puppioil
POIHI 11310 12 00/6 Mochsnumj ol c«i(Jioy«scul«i
diMisa Ti»tm«nl ol dopiessed oidiac output lollowinj
hurt aui|*ry (chiidian. puppies)
POIHI 1215' 11 OOb? Functions and mechanisms ol cell
mambiane ion tianspoit [lectiophysiolojical
investijations ol synthetic stiands ol heart muscles (lats)
' POIHI 123n 10 0005 Caidiopulmonary physiolojy and
palhophysiolojy Chaiacteiualion ol total and neonatal
ntyocaidium (human, cats)
ROIHL 13237 09 [lythrocytes dutint earlv development
(human, animals)
P50HL U214 07 0025 Newborn lung centei lor hyaline
membrane disease Pulmonaiy vasculat peimeabilily and
lung watei Hyaline membcane disease (sheep)
P50HI 14214 07 0026 Newboin lung centei loi hyaline
membiane disease Hemodynamic studies ol HMD
Prostaglandins production and blockers (lambs)
P50HL 14214 07 0027 Newboin lung centei toi hyaline
membiane disease Oial laiyngeal chemoreceplois and
lespiiatory lailuie in newborns (human, sheep)
P50HL 14214 07 0028 Newboin lung centei loi hyaline
membiane disease Relationship ol tiace metals to
respiialoiy lailure (dog, sheep, human)
P50HL 14214 07 0029 Newboin lung centei loi hyaline
membiane disease The diving rellex Peiinatal asphynia,
pulmonary ischemia and HMD (sheep)
P50HL 14214-07 0035 Newborn lung centei toi hyaline
membiane disease Coie Animal care lacihty
POIHL 1438807 0159 Regulation ot the circulation in
pathological states Early drug and diet interventions and
blood piessuie development (lats)
POIHL 1438807 0188 Regulation ol the circulation in
pathological states Renin angiotensin system in the sheep
letus
POIHL 1438807 0196 Regulation ol the circulation in
pathological states ■ Altered vascular responsiveness in
spontaneous hypertension (rats)
POIHL 1438807 0197 Regulation ol the circulation in
pathological states Altered vascular reactivity in
pathogenesis ol spontaneous hypertension (rats)
•* ROlHL-1466307 Pulmonary oxygen toxicity m newborn
lung (human, mice)
•* ROlHL-1544406 Neonatal development of adrenergic
receptor mechanisms (pigs)
P60HL15999-05 0019 Miami comprehensive sicKle cell
center - Fetal-adult hemoglobin switch (mouse, monkey)
R01HL16022-05 Determinants of the ventilatory response
to hypoxia (goats, cats)
POlHL-1611705 0001 Ion movements and membranes in
cardiovascular control - Developmental studies of
contractile cell junctions (rats, rabbits, elasmobranch)
POlHL-16137-05 0013 Alveolar biology - Development and
pathology of surfactant-Formation of alveolar (rabbits,
sheep)
** R01HL16152-06 Electrophysiology of neonatal to adult
heart (cats, frogs, guinea pigs)
POlHL-17430-05 0001 Control of coagulation - Porcine
von Willebrand's disease
♦* ROlHL-1762903 Developmental aspects of cardiovascular
function (human, cats, rabbits)
R01HL17800-04 Pulmonary reflexes -Central pathways
(cats, dogs, rabbits)
ROlHL-17865-04 Studies on aging-Effects of sex
hormones (rats, dogs)
ROlHL-18028-03 Absorption of nonvolatile compounds
from the lung
** ROlHL-18032-03 Development of normal and myopathic
mammalian heart (hamsters)
** ROlHL-18952-03 Metabolism in perfused fetal and
newborn rabbit lungs
P50HL-19185-02 0004 Pulmonary SCOR-Neonatal
respiratory distress syndromes ■ Fluid and protein transport
in fetal and newborn lung (sheep, rabbits)
P50HL-19187-02 0013 Pediatric pulmonary SCOR -Hyaline
membrane disease ■ Research resources core
P50HL-19190-02 0006 Pulmonary SCOR-Pathophysiology,
management of IRDS - Asphyxia-Respiratory control (dogs)
P50HL-19190-02 0007 Pulmonary SCOR-Pathophysiology,
management of IRDS - Asphyxia-Cerebral metabolism (dog,
ROlHL-19333-03 Hematopoietic chimcrism (mice, monkey)
P50HL-19362-02 0012 A/S SCOR -Atherosclerosis in
nonhuman primates - Induction of chronic hypertension by
salt loading (baboon)
R01HL19486-03 Oipole moment measurement of cardiac
mass (rabbits, pigs) •
ROlHL-19684-03 Histotypic lung culture in circumfusion
systems (mice)
** POlHL-19717-02 0023 Response of the lung to injury -
Postnatal lung development-Cells, connective tissue and
physiology (animals)
•* POlHL-19717-02 0024 Response of the lung to injury ■
Formation of lung alveoli (rats)
** POlHL-19717-02 0025 Response of the lung to injury -
Role of oxygen in regulation of lung growth and
development (rats)
•* P01HL19717-02 0026 Response of the lung to injury -
Protein depletion and postnatal lung development (rats)
'• POIHI 19/17 02 0027 Retponit ol the lung to iniuiy
Hoimone control ol lung growth and development (lattl
ROIHl 20610 02 Neive growth (actoi and obitiuclive
caidiomyopathy (dogs)
ROIHI 20961 02 Hemoglobin Y chain genes f volution and
inducibility (monkeys, human)
ROIHI 211/6 02 Phospholipid exchange proteins in lung
tissue (lambs)
ROIHI 21673 01 Pathophysiology ol venous changes in
hypertension dais. labbits. human, dogs)
R23HI 21/83 01 Ionic control ol contiaclilily in anoxic
myocardium (rabbits, lals)
ROIHI 22500 01 Conveision of choline to
phosphatidylcholine in lung (labbits, pigs)
ROIHL 22664 01 Regulation of myocaidial cell growth
(rats, guinea pigs)
ROIHL 22859 01 Effect of carbon monoxide on the
developing heart (rats)
** ROIHL 2302501 Adaptive heart growth in neonates and
adults (rats)
ROIHL 2373604 Sickle cell anemia and hemoglobin
synthesis (monkeys)
•• ROIHL 2398001 Effects of digoxin theiapy in newboin
and adult sheep
AGE (ANIMAl), INFANTS PREMATURE AND lOW
BIRTH WEIGHT
SEE ALSO PREGNANCY DISORDERS. EMBRYO FETAL GROWTH
DEVELOPMENT DISORDERS (SEE ALSO
APPROPRIATE SP:CIFICS)
P50HL 14214 07 0025 Newboin lung centei foi hyaline
membiane disease Pulmonaiy vasculai peimeabilily and
lung water Hyaline membrane disease (sheep)
P50HL 14214 07 0026 Newborn lung center for hyaline
membrane disease - Hemodynamic studies of HMD-
Prostaglandins production and blockers (lambs)
P50HL 1421407 0029 Newborn lung centei foi hyaline
membiane disease The diving letlex -Perinatal asphyxia,
pulmonary ischemia and HMO (sheep)
P50HL-142U07 0035 Newboin lung centei lor hyaline
membrane disease Core Animal care facility
P50HL 19185-02 0004 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Fluid and protein transport
in fetal and newborn lung (sheep, rabbits)
M P50HL-19187-02 Pediatric pulmonary SCOR -Hyaline
membrane disease
P50HL 19187-02 0001 Pediatric pulmonary SCOR -Hyaline
membiane disease - Hyaline membrane disease-Changes
in lung mechanics and gas exchange (monkeys)
P50HL-19187-02 0002 Pediatric pulmonary SCOR-Hyaline
membrane disease ■ Hyaline membrane disease -Alterations
in surface active material (monkeys)
P50HL-19187-02 0003 Pediatric pulmonary SCOR-Hyaline
membiane disease Hyaline membiane disease-
Ultiastructurc studies (monkey)
P50HL-19187-02 0011 Pediatric pulmonary SCOR-Hyaline
membrane disease - Effects of hypoxia and hypercapnia on
developing nervous system (monkey, human)
** P50HL-19187-02 0013 Pediatric pulmonary SCOR-Hyaline
membrane disease - Research resources core
AGE (ANIMAl), JUVENILE (POST-INFANCY TO
PUBERTY)
P50HL-14164-07 0041 A/S SCOR -Comparative and
experimental atherosclerosis - Nonhuman primate pediatric
atherosclerosis risk factor
AGE (ANIMAL), MATURE (ADULT)
ROlHL-222 73-01 Oral and lung absorption of nitroglycerin
(rats)
AGE (ANIMAL), PUBERTY
ROlHL-22273-01 Oral and lung absorption of nitroglycerin
(rats)
AGE (ANIMAL), WEANLING
ROlHL-2227301 Oral and lung absorption of nitroglycerin
(rats)
AGE (HUMAN)
SEE ALSO AGE (ANIMAL)
SEE ALSO CELL AGE
SEE ALSO CHILDREN
SEE ALSO EMBRYOLOGY
SEE ALSO PREGNANCY. EMBRYO-FETUS
SEE ALSO PREGNANCY. EMBRYO-FETUS, GESTATIONAL AGE
POlHL-03 174-23 0006 Mechanisms of acute vascular
reaction to injury - Atherosclerotic plaque studies using
mosaic analysis (human)
ROlHL-03429-18 Central nervous system and coronary
heart disease (human)
POlHL-063 14-17 0066 Immunologic mechanisms in
cardiovascular disease • Sensitization, cell-mediated
cytotoxicity, role of lymphocytes (human, mice)
POlHL-08974-14 0028 Natural and experimental
atherosclerosis - Geographic pathology of atherosclerosis
and coronary heart disease (human)
R01HL13632-08 Vascular changes in diabetes mellitus
(human)
POlHL-14388-07 0208 Regulation of the circulation in
pathological states - Baroreceptor reflex function in normal
and hypertensive man
Af.l
HOIMI 14414 0/ 0008 I nviionmtntil inllutnif. on
caidwmpinloiy and cellulii function* ln.i|«tit« ot
iwimming (human)
ROIHI r)124 05 Caneiii ol hypfrlfn^on in unil diwaw
(human dogtl
ROIHI 15808 06 Role ol »n|iottniinoitn in hyptrteniion
and stroke (human, iibbitt)
POIHI 1583? 06 0004 Chemical stiuttuial piedupotilioni
to lung iniury Proteolytic activity leucocyte* m patient*
with obstiutlive lung di*ea*e
POIHI 16118 06 0003 Study of emphyiema Degradation
ol collagen and elastin (human, hamitei*. mice)
ROIHI 16588 05 Collagen lyntheji* in atheio»ti«io«it
(dogs. lals. labbils, human)
P60HI 1/292 04 0003 Veimont Lung Centei Subclinical
pulmonary disease in a luial environment (numan)
ROIHI 1/408 03 Fiesh blood ihcology Relation to
cardiovascular risk (human)
• POIHI 1/419 04 0003 Studies on mechanisms of
hemostasis Chaiacteri/alion of fibrinogen (human)
ROIHI 17732 03 Peripheral venomotoi control in Iheimal
stiess (human!
ROIHL 18692 03 Glycosaminoglycans and lipoproteins ot
human plasma
ROIHL 1880504 0007 Sudden cardiac death and the
onset ol myocardial infaiclion Analysis of pathologic
factois involved in sudden death (human)
ROIHL 19869 03 Antecedents of adolescent hypertension
(human)
ROIHL 1987003 Hypertensive progeny-Physical and
humoial piecursor search
ROIHL 19898 03 Oesferrioxamine therapy in thalassemia
(dogs, rats, children)
ROIHL 19929 03 High blood piessuie in the young,
prevalence and precursors (human)
ROIHL 20179 02 Epidemiology of sudden cardiac death
among women
ROIHL 20381 03 Long term study ol diabetic vascular
disease (human)
ROIHL 20471-03 Atherosclerosis and diabetes mellitus
(human)
ROIHL 2101002 Glycemia. other traits and CV death in
40.000 persons
ROlHL-21352-02 Community studies of obstructive lung
disease (human)
ROlHL-21548-01 Pathogenesis of pulmonary
thromboembolic disease (human, mammals)
ROlHL-22739-01 Evolution and progression of pediatric
atherosclerosis
ROlHL-22809-01 Coronary-prone behavior and
cardiovascular reactivity (human)
ROIHL 23600 01 Ions, water, and hypertension (human,
dogs, rats)
ROlHL-23631-01 Immunogenetic factors in allergic
respiratory diseases (human)
NOlHR-32900-09 Pilot study to standardize the
measurement of 'closing volume' (human)
NOlHR-32902-07 Pilot study to standardize the
measurement of closing volume (human)
NOlHR-62910-02 Fibroprotein networks of pulmonary
alveolar wall (human)
NOlHV-22931-14 Therapy for hypertension in general
population
NOlHV-22937-07 Therapy for hypertension in general
population
NOlHV-22938-11 Therapy for hypertension in general
population
AGE (HUMAN), ADULT
SEE ALSO AGING
POlHL-11310-12 0057 Mechanisms of cardiovascular
disease - Blood pressure reduction after heart surgery in
adults (human)
** P01HL-U310-12 0082 Mechanisms ol cardiovascular
disease - Myocardial function in adult congenital heart
disease (human)
** POlHL-11310-12 0083 Mechanisms of cardiovascular
disease - Ventricular volume and hemodynamics in adult
congenital heart disease
P60HL-15158-07 0011 Comprehensive sickle cell center ■
Clinical services -Adult patients
P60HL15162-07 0001 Comprehensive sickle cell center -
Core program-Patient care
P60HL- 15996-06 0008 Cincinnati comprehensive sickle
cell center - Patient care (children, adults)
P60HL-16008-06 0001 Wayne State University
comprehensive sickle cell center - Patient care system
(children, adults)
POlHL-17419-04 0003 Studies on mechanisms of
hemostasis - Characterization of fibrinogen (human)
ROlHL-17580-04 The impact of stress on coronary heart
disease (men)
ROlHL-18144-03 Preprocessor system for cardiograms
(human)
ROlHL-20961-02 Hemoglobin Y chain genes-Evolution and
inducibility (monkeys, human)
ROlHL-22123-02 The rale of the red cell in diabetic
atherosclerosis (human)
R01HL-22296-01 Autonomic mechanisms in man
ROlHL-22514-01 Behavior patterns, stress, and
catecholamines
N01HV-72917-00 Plasma lipoproteins in identical twins
(conid)
•Excludes routine methodology OR covers only general projects which preclude
"Oriented significantly to above subject.
indexing at the specific level.
HI Grant has subprajects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
AGE
AGE (HUAAAN), ADUIT, MIDDLE AGE (45 TO 64
YRS)
POlHL-08974-14 0005 Natural and experimental
atherosclerosis ■ Atherosclerosis, coronary heart disease
and sudden death (human)
ROlHL-17818-05 Metabolism of cholesterol and cholesterol
in man (also rats, monkeys)
ROlHL-18738-02 Prevention of postoperative venous
thrombi (human, cattle)
ROlHL-18776-04 Prevention of acute and fatal
cardiovascular disease (human)
ROlHL-19839-09 Factors in youth predisposing to chronic
diseases (former college students)
Nmuuloo^^^Sl ^''°'°^^ "' myocardial infaction (human)
NOlHV-22971-07 Prevention of coronary heart disease
(human)
NOlHV-22977-08 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22979-07 Intervention trial for the prevention of
coronary heart disease (human)
N01HV-22980-06 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22981-10 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22982-07 Intervention trial for prevention of
coronary heart disease (human)
NOlHV-2298307 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-33 105-09 Intervention trial for prevention of
coronary heart disease (human)
NOlHV-33106-06 Intervention trial for the prevention of
coronary heart disease (human)
AGE (HUMAN), ADULT, OLD AGE (65 TO 99
YRS)
POlHL-08805-15 0044 Regulation of ventilation and
pulmonary circulation - Neurochemical interactions in
respiratory control (human, dogs, goats)
AGE (HUMAN), ADULT, YOUNG (21 TO 44 YRS)
ROlHL-19839-09 Factors in youth predisposing to chronic
diseases (former college students)
R01HL19858-03 UMMC -Blood pressure precursors and
consequences (human)
ROlHL-19929-03 High blood pressure in the young,
prevalence and precursors (human)
ROlHL-19962-03 High blood pressure in young people in
Tecumseh
ROlHL-22740-01 Behavior and cardiovascular disease-
Basic mechanisms (human)
AGE (HUMAN), CHILDREN
SEE CHILDREN
AGE PIGMENT
SEE LIPOFUSCIN-CEROID
AGGLUTININS
SEE IMMUNOLOGY, ANTIBODIES, AGGLUTININS
AGGLUTININS, PLANT
SEE PLANTS PROTEINS, LECTINS
AGGREGATES (CHEMISTRY)
SEE CHEMICAL AGGREGATES
AGGREGATION, CELLULAR
SEE CELL-CELL INTERACTION, CELL AGGREGATION
AGGRESSION
SEE PSYCHOLOGY, BEHAVIOR, AGGRESSION
AGGRESSIVE OUTREACH
SEE HEALTH CARE SERVICES, CASE FINDING AND OUTREACH
AGING
ROlHL-01979-22 Arteriosclerosis in zoo animals on
controlled diets (animals)
POlHL-06296-18 0005 Cardiovascular and pulmonary
adaptation to stress - Regulation of ventricular
performance (animals)
ROIHL-06736-18 Biogenic-mechanical factors in
microcirculation (rats, gerbils)
POlHL-06835-17 0064 Cardiovascular disease - Studies
in atherosclerosis (human, animals)
POlHL-07896-15 0055 Environmental biomedical research
program - Cerebral blood flow by Xenon-133 inhalation
(human)
P01HL-08899-I4 0044 Tolerance to respiratory gases in
health and disease - Influence of high oxygen pressures on
cognition and performance
•* POIHL-08899 14 0046 Tolerance to respiratory gases in
health and disease - Studies in senile elderly individuals
^^ ROlHL-10009 13 Regional lung function in man
ROlHL-10018 11 Effect of aging on beating heart cells in
culture (rats)
R01HL-I1551-n RNA and protein synthesis In repair of
heart injury (mice, rats)
ROlHL-12711-09 Mathematical approach to cardiovascular
mechanics (human, animals)
P01HL-13262-G7 0016 Arterial v»all in atherosclerosis -
Lipids in elastin preparations from atherosclerotic plaques
(human, animals)
ROlHL-13626-06 Lipoprotein lipase and lipoprotein
removal (human, rats, bacteria)
•S^^'SXtre'su^^;"'^'^""^'-'™^^^
8
P50HL-14153-07 0010 Johns Hopkins Lung Center-
Chronic diseases of airways • Risk factors for airviays
obstruction in a rural community (human)
ROlHL-14495-05 Solid and structural mechanics of lungs
(mammals)
P0IHL-14580-07 0002 Program project in respiratory
mechanics - Airway aerodynamics (human, dogs)
ROlHL-1504706 Digital computer analysis of the
electrocardiogram (human)
ROlHL-16037-06 Molecular properties of cardiac
adrenergic receptors
ROlHL-16330-06 Aging-tissue injury and repair (rats)
R01HL-16421-08 Determinants of RBC deformability and
capillary flow (human, mice)
ROlHL-16768-04 The sympathetic nervous system and the
arterial wall (rabbits, pigeons)
ROlHL-16952-05 Cardiovascular pathology (rats, rabbits)
R01HL-17576-04 Role of sphingomyelin in biomembranes
and bilayers (rats, other mammals)
ROlHL-17706-04 Psychosocial hypertension,
catecholamines and drugs (mice)
ROlHL-17865-04 Studies on aging-Effects of sex
hormones (rats, dogs)
R0IHL18284-04 Aging erythrocytes -Bio-recognition and
elimination (monkeys)
ROIHL 1861003 Early intervention of age related arterial
changes (pigeon)
ROlHL-18629-04 Influence of aging and hypertension on
the myocardium (rats)
POlHL-19242-02 0001 Study of vascular smooth muscle -
Energy metabolism and protein turnover In vascular smooth
muscle (rats)
POlHL-19717-02 0018 Response of the lung to injury -
Lung mechanics and connective tissue composition in
human emphysema
ROlHL-19864-03 0001 Blood pressure of children and
young adults - Follow up of students from Dormont
Pennsylvania
ROlHL-20197-02 Maintenance and repair of vascular
endothelium (human, animals)
R01HL-2G373-02 Cardiovascular aging in young men and
women
ROlHL-20546-02 Chemical analysis of human arterial
elastin
ROlHL-20564-02 Pathogenesis of peripheral arterial
disease (rats, rabbits)
ROlHL-20572-02 0003 Hemodynamic relations to
metabolism in hypertension ■ Cardiac output and organ
blood flow in hypertension (rats)
ROlHL-20875-02 Chronic obstructive pulmonary disease-
Famihal/genetic (human)
R23HL-21393-01 Cardiac adaptation to aging and stress
(rats)
ROlHL-21592-01 Lipoproteins and coagulation factors in
atherosclerosis (pigeons)
ROIHL-22040-01 Regulation of lysyl-cross-linking in
vascular tissue (rats, turkeys)
ROlHL-2231301 Lung elastic recoil-Age and disease
(human)
ROlHL-22671-01 Removal of senescent and stored human
red cells
ROlHL-22729-01 Intracellular degradation of newly
synthesized collagen (human, chick, rabbit)
ROlHL-22750-01 Digoxin in heart failure with sinus
rhythm (human)
ROlHL-22854-01 Noninvasive blood pressure
measurement (rats)
ROlHL-22883-01 Lung epithelial cell interactions in vitro
ROlHL-23994-01 Biochemical properties of human cardiac
myosin
AGING, LONGEVITY
POlHL-06835-17 0024 Cardiovascular disease - Studies
on the obese spontaneously hypertensive rat
AGLYCONES OF STEROIDS GLYCOSIDES
SEE STEROIDS GLYCOSIDES AGLYCONES
AGONISTIC BEHAVIOR
SEE PSYCHOLOGY, BEHAVIOR, AGGRESSION
AGRANULOCYTOSIS
SEE BLOOD AND RE DISORDERS, LEUKOCYTE DISORDERS
AGRANULOCYTOSIS
AGRICULTURAL W/ORKERS
SEE OCCUPATIONS, AGRICULTURAL WORKERS
A-H HYPERTENSION
SEE CARDIOVASCUUR DISO.'<DERS. HYPERfENSION
(SYSTEMIC), NEUROGENIC HYPERTENSION
AIDS, HEALTH PERSONNEL
SEE HEALTH SCIENCES PROFESSIONS, HEALTH (CARE)
PERSONNEL ALLIED
AIDS, PSYCHIATRIC
SEE MENTAL HEALTH PERSONNEL ADJUNCT
AIR
SEE ENVIRONMENT, ATMOSPHERE (WEATHER)
AIR CONDITIONING, HEATING, VENTILATION
SEE ENVIRONMENT CONTROLLED
ALB
AIR EMBOLISM
SEE CARDIOVASCULAR DISORDERS. EMBOLISM, AIR
AIR FLOW/METERS RESPIRATORY
SEE RESPIRATORY DISORDERS DIAGNOSIS. RESPIRATORY
AIRFLOW MEASUREMENTS*
AIR MONITORING
SEE AIR SAMPLING-MONITORING
AIR POLLUTION
SEE ALSO HYPERSENSITIVITY. ALLERGENS AIRBORNE
SEE ALSO PHYSICAL AND/OR CHEMICAL AGENTS
INTERACTION (BIOLOGICAL AND ECOLOGICAL)
POLLUTANTS INTERACTION
SEE ALSO PHYSICAL PROPERTIES. PARTICLES DUST
SEE ALSO RESPIRATORY DISORDERS. RESPIRATORY SYSTEM
TOXINS
P50HL-1413607 0016 Pulmonary SCOR -Airways
obstructive diseases Environmental factors in airways
obstructive diseases (human)
P50HL-14212-07 0015 Correlated studies of pulmonary
fibrosis - Pulmonary defense mechanisms and fibrotic lung
disease (rodents, rabbits)
P50HL15092-07 0010 Immune and fibrotic response to
occupational environments - Characterization of toluene
diisocyanate in industrial environments
R01HL-16C29-05 Bio-organic chemistry of ozone, nitrogen
dioxide and tobacco smoke
ROlHL-16674-05 Airborne metals and lung permeability
(bullfrogs, rats)
R01HL17921-04 Peroxy radicals to prostaglandins in
vessels and lung
ROlHL-18308-03 Comprehensive studies of mucociliary
transport (dogs)
ROlHL-19746-03 Proliferation and differentiation of
alveolar macrophages (mice, hamsters)
" ROlHL-21008-02 Effect of pollutants on organotypic lung
cultures (rats)
•* ROlHL-21009.02 Effects of air pollutants on lung cells In
culture (rats)
ROlHL-21352-02 Community studies of obstructive lung
disease (human)
AIR POLLUTION CONTROL
" POlHL-19737.02 0009 Cellular and molecular aspects of
respiratory physiology - Regulation of tissue oxygen tension
and body carbon monoxide stores (human, dogs)
AIR SAMPLING-MONITORING
" P50HL-15092-07 0001 Immune and fibrotic response to
occupational environments ■ X-ray diffraction study-Dust
exposure in asbestos cement products manufacturing
P50HL-15092-07 0002 Immune and fibrotic response to
occupational environments - Longitudinal study of
sandblasters silicosis (human)
" P50HL- 15092-07 0010 Immune and fibrotic response to
occupational environments - Characterization of toluene
diisocyanate in industrial environments
P50HL-15092-07 0011 Immune and fibrotic response to
occupational environments - Respiratory and immunologic
responses in coffee plant workers
P50HL- 15092-07 0012 Immune and fibrotic response to
occupational environments - Longitudinal evaluation of
workers exposed to cotton dust
AIRBORNE ALLERGENS
SEE HYPERSENSITIVITY, ALLERGENS AIRBORNE
AIRCRAFT FLIGHT
SEE ENVIRONMENT. EXTRATERRESTRIAL. SUPRATERRESTRIAL
AJMALINE
SEE ALKALOIDS, RAUWOLFIA TYPE, AJMALINE
ALANINE
SEE AMINO ACIDS, ALANINE
L-ALANINE:2-OXOGLUTARATE
AMINOTRANSFERASE
SEE AMINOTRANSFERASES, ALANINE TRANSAMINASE
ALANINE TRANSAMINASE
SEE AMINOTRANSFERASES. ALANINE TRANSAMINASE
ALBUMINOIDS
M POlHL-13262-07 Arterial wall in atherosclerosis
ROlHL-17865-04 Studies on aging-Effects of sex
hormones (rats, dogs)
ROlHL-17909-04 Drug treatment of vascular scleroprotein
defects (human, turkeys)
ALBUMINOIDS, COLLAGEN
SEE ALSO ALBUMINOIDS, GELATIN
" ROlHL-01803-23 0016 Arteriosclerosis, glomerulonephritis
rheumatic fever - Synthesis of basement membrane
collagen by endothelial cells (human)
ROlHL-02942-22 Biochemistry of cardiovascular connective
tissue (human, cattle, primates)
POlHL-03 174-23 0005 Mechanisms of acute vascular
reaction to injury - Renal small vessel didease-Cell and
matrix response (human, mice)
POlHL-03174-23 0012 Mechanisms of acute vascular
reaction to injury - Human atherosclerotic plaque in organ
culture
at the specific level.
M Grant has subp;
See Appendix foi ii..
describing specific research aspects.
■ ' - ti. mp and grant number
(contd)
AlB
• roitll Ob83S W 006? Cstdiovasculjt di««5« Kola ol
tollfltfii in alhtioscleiosis (dogs, pigfons)
ROIHIOO'IU IJ lh« niyociidium in diabetes mtllilus
(dogs monkeys)
ROIHI 10018 11 tiled ol aging on beating heirt cells in
cultiiie (lals) . . ,
ROIHI IIIW 1? Vasculai physiology (human, cats dogs)
• POIHI 11310 1? 0106 Mechanisms ol caidiovnscular
disease Biochemical chaiacteii/ation ol the collagens in
vasculai tissue (catte)
ROIHI 11614 11 Iiace elements in nutrition (chickens.
lats, human)
• ROIHI 1?561 11 Cardiovasculat studies on coppei
deliciency (swine)
• POIHL 13?62 0; 0012 Afletial wall in atheroscleiosis
Chaiactetuation ol connective tissue components (animals)
" POIHI 13262 0? OOlb Arterial wall in alheiosclciosis
Ciosslinkage biosynthesis in aoitic elastm and collagen
(animals)
POIHL 13262 0/ 002!) Arterial wall in atherosclerosis
Phospholipid and cholesterol esters
'* ROIHL 14126 U fttect ol (unction on grails and implants
ol collagen (dogs monkeys)
•* P50HL 14164 0/ 0036 A/S SCOR Comparative and
experimental atherosclerosis Connective tissue
metabolism Interaction with arterial metabolism (monkeys)
♦* P50HI 14212 0? 0004 Correlated studies ol pulmonary
fibrosis Collagen metabolism in lung tissue and lung
cells (human, animal)
P50HL 1421207 0016 Correlated studies of pulmonary
fibrosis Role ol pulmonary alveolar macrophages in
fibrosis (human, rabbit)
R01H1143440? Platelet function and adenine nucleotide
metabolism (human)
ROIHL 1469707 Role of platelet membranes in
hemostasis (human)
ROIHL 15013-07 Lung oxidative metabolism and energy
production (rodents, rabbits)
** P50HL-1506107 0004 Response of lung to ln|ur>
Biochemical abnormalities in connective tissues (rats)
P50HL-1506207 0020 Study of lipoproteins, arteiv wall,
and atherosclerosis ■ Artery wall reactions Elevated
pressure and hyperlipemia (monkey)
P50HL 15103-07 0014 A/S SCOR -Early natural history of
arteriosclerosis Biochemistry of atherosclerotic lesions
(monkeys, human, cattle)
** ROIHL 15335 06 The nature of the collagen-platelet
interaction (animals)
ROlHL-15448-06 Surgical and metabolic aspects of
venous grafts, (dogs, monkeys, rabbits)
** R01HL15478-05 Lipid flux and collagen synthesis in
atherosclerosis (rabbits)
M POlHL-15832-06 Chemical-structural predispositions to
lung injury
** P01HL15832-06 0001 Chemical-structural predispositions
to lung injury - Chemical composition of lung connective
tissue proteins (human, animals)
POlHL-15832-06 0002 Chemical structural predispositions
to lung iniury - Connective tissue in lung in development
and repair of in)ury (human, rats, mice)
POIHL 15832-06 0008 Chemical structural predispositions
to lung injury - Interstitial fibrosis -Connective tissue
components in normal and diseased lungs
M POlHL-16118-06 Study of emphysema
** P01HL16118 06 0003 Study of emphysema - Degradation
of collagen and elastm (human, hamsters, mice)
" P01HL16118-06 0004 Study of emphysema Metabolic
activity of pulmonary connective tissue (human, hamsters)
POIHL 1611806 0006 Study of emphysema Metabolism
of elastin (hamsters)
ROlHL-16206-04 Regression of atherosclerotic plaques
(monkeys, dogs)
** ROlHL-16355 05 Reactions of thrombin and collagen with
platelets (human)
ROlHL-16437 05 Drug treatment of atherosclerosis
(rabbits, monkeys)
** R01HL16588-05 Collagen synthesis in atherosclerosis
(dogs, rats, rabbits, human)
ROlHL-16768 04 The sympathetic nervous system and the
arterial wall (rabbits, pigeons)
** ROlHL-16904-03 Regulation of smooth muscle cells in
arteriosclerosis (rabbit aorta)
ROIHL 17402-04 Mechanism of contact activation of
intrinsic clotting (human)
POlHL-17430-05 0007 Control of coagulation - Platelet
adhesion, aggregation, ultrastructure in flowing blood
(human, animals)
** ROlHL-17525-03 Molecular basis of collagen-platelet
interaction (human, rat)
ROlHL-17597-05 Role of plasma lipoproteins in
atherosclerosis (swine, human)
** ROlHL-17721 04 Effect of sex hormones on vascular
connective tissue (rats)
R01HL-I7865-04 Studies on aging-Effects of sex
hormones (rats, dogs)
ROIHL 17909-04 Drug treatment of vascular scleroprotein
defects (human, turkeys)
P50HL-18318 03 0014 Pathogenesis and complications of
hypertension - Arterial metabolism and atherogenesis (rat,
rabbit)
P50MI 18JI8 0.1 UUl'i Palhogentsii ind complication-, ol
hypertension Culluied smuuth muscle cells and
miciovessel met.ibnlism (mammals)
POIHI 18176 03 0001 Ihiombosis research program
pioiecl Platelet damage from physical forces and
artidcial surfaces (human)
' POIHI 18576 01 0004 thrombosis research program
project Mechanism and control ol collagen olateltt
interaction
■ ROIHL 18593 03 Chaiacterualion ol heart valve collagen
(human, pig)
POIHL 18645 03 0001 Biology of the artery wall and
atherosclerosis Primate arterial smooth muscle and
atherosclerosis
POIHL 18645 03 0003 Biology ol the artery wall and
atherosclerosis Synthesis o' cnnneclive tissue proteins by
smooth muscle cells (human, monkeys)
• ROIHI 18650 03 Platelet collagen interaction (human)
ROIHL 18714 04 Cardiovascular matrix Morphogenesis
and maturation (human, chick embryo, mammal)
POIHL 18827 02 0001 Platelet vessel wall inleiactions in
thiombogenesis Role of endothelial cells in the production
of thrombi (human, cattle)
' POIHI 18827 02 0002 Platelet vessel wall interactions in
thrombogenesis Interactions nl vessel wall
macromolecules with factor XII (human, rats)
P50HL18828 03 0002 Specialized center of research in
thrombosis Endothelial cell biology (humin. guinea pig)
P50HL 18828-03 0004 Specialized center of research in
thrombosis Membrane changes in platelet physiology Role
ol complement (mice, human)
•• ROlHL-1925202 Vascular connective tissue -Role in
atherosclerosis (rabbits)
ROIHL 19425-03 Cardiac function in hypertrophy (dog)
ROIHL 19537 03 Detection of myocardial injury with
ultrasound (dogs)
** ROlHL-19668 03 Biochemistry of lung connective tissue
(rats)
POlHL-19717 02 0001 Response of the lung to injury
Lung elastic tissue (animals)
•* POIHL 19717 02 0002 Response of the lung to injury
Prolyl hydroxylase, lysyl hydroxylase and lung collagen
biosynthesis (rabbits)
POIHL 19717 02 0004 Response of the lung to injury -
Regulatory and physical chemical properties of lung lysyl
oxidase (animals)
POIHL 1971702 0007 Response of the lung to injury
Cellular level studies of prostaglandin-like molecules
(cattle)
POlHL-19717-02 0008 Response of the lung to injury -
Experimental models of lung disease
POlHL-19717-02 0028 Response of the lung to injury -
Compensatory growth of the lung following pneumonectomy
(rabbits)
** ROIHL 19731-03 Collagen in interstitial fibrosis of lung
(human)
R01HL-20104 03 Pulmonary granulomatous inflammations
(mice)
** R01HL20114 02 Collagen-platelet interaction and human
aorta collagen (human)
ROIHL 20426 03 Myocardial function in diabetes mellitus
(dog, rat)
R0IHL20447-03 Connective tissue and diabetic vascular
disease (human)
ROIHL 20635 03 Factors in lung development (rat and
chick embryo)
ROIHL 21095-02 Enzymes of M tuberculosis and
obstructive lung disease (human, rodents)
P23HL 21134-02 Immune function and fibrogenesis in
silicosis (guinea pigs)
R23HL21225-02 Connective tissue precursor molecules in
the lung (rabbits, hamsters)
*• ROIHL 21303 02 Collagen synthesis by cultured human
vascular cells
ROIHL 21498-02 Pathophysiology of edema (rats, cats)
*• R23HL 21504-02 Collagen synthesis in pulmonary fibrosis
cells (human)
ROIHL 21617-02 Biochemistry of lung proteoglycans
(rabbits, cattle)
R01HL-21G22-02 Structure and interactions of lung
proteoglycans (cattle)
ROlHL-21626 01 Proteoglycans of animal lung
parenchyma (cattle, pigs, rabbits)
ROlHL-21641 02 Structural studies of lung proteoglycans
(pigs, cattle, rabbits)
ROlHL-21644-01 Fibronectin and related glycoproteins
(human, rodents)
ROlHL-21646-02 Biosynthesis of fractionated
proteoglycans of lung (rabbits)
ROIHL 21649-01 Biochemistry of lung proteoglycans
(mammals)
" R23HL-2166301 Regulation of collagen biosynthesis
(chick, embryo)
** R01HL21665-01 Collagen polymorphism and arterial
structure (monkeys, guinea pigs)
'* ROIHL 21988-01 Biochemistry of human platelet
chemotaxis
" R01HL2208120 The mechanism of collagen formation
(human, cattle)
ROlHL-22623-01 Polyamines cellular mediators of
atherogenesis (human)
AlB
*• ROIHI ??/?90l Inlficellulii dtgridalion ol newly
lynlheii/ed follijen (humin. chick iibbill
ROIHI 22/39 01 Evolution end progiemon ol pediiIrK
tthaioscleioM'.
R23H1 ??745 01 Vawulai mech»nif< and itrutluie in
hypertension (miniatuie swine)
ROIHI 23547 01 Pulmonary vasculK smooth muwie cell
dynamics (rat labbil)
NOIHR 62910 02 Fibroptolein nelworlu ol pulmonery
alveolar wall (human)
NO I HV 42969 06 Interactions of nalurel and chemicelly
modilied biopolymeis with blood (dogil
•• NOIHV 42984 05 Interactions ol modified biopolymeri with
blood (humans, rats)
•• NOIHV 5290/ 04 Interactions ol platelets with collagens
(human mammals)
ALBUMINOIDS, COLLAGEN, PROCOLLAGEN
•• ROIHll/55104 Biosynthesis and metabolism ol
procollagen (human, monkeys, mice)
•' POIHI 18827 02 0002 Platelet vessel wall interactions in
thrombogenesis Interactions ol vessel wall
macromolecules with factor XII (human, rats)
POIHL 19717 02 0001 Response of the lung to injury •
Lung elastic tissue (animals)
POIHL 19717 02 0002 Response ol the lung to injury ■
Prolyl hydroxylase, lysyl hydroxylase and lung collagen
biosynthesis (rabbits)
ROIHL 21303 02 Collagen synthesis by cultured human
vascular cells ^ ^ ,
ROIHL 2166501 Collagen polymorphism and arterial
structure (monkeys, guinea pigs)
ALBUMINOIDS, COLLAGEN, TROPOCOILAGEN
ROIHL 17551-04 Biosynthesis and metabolism of
procollagen (human, monkeys, mice)
** R23HL 19594 01 Tropocollagen and tropoelastin uptake in
lung cells (human)
POIHL 19717 02 0004 Response of the lung to injuiy -
Regulatory and physical-chemical properties of lung lysyl
oxidase (animals)
ROlHL-21622-02 Structure and interactions ol lung
proteoglycans (cattle)
ALBUMINOIDS, ELASTIN
R01HL-02942 22 Biochemistry of cardiovascular connective
tissue (human, cattle, primates)
ROIHL 11614 11 Trace elements in nutrition (chickens,
rats, human)
" ROIHL 11963 10 Biochemistry of blood vessel formation
and disease (swine)
♦* ROIHL 12561 11 Cardiovascular studies on copper
deficiency (swine)
*♦ POlHL-13262-07 0012 Arterial wall in atherosclerosis •
Characterization of connective tissue components (animals)
** POlHL-1326207 0015 Arterial wall in atherosclerosis
Crosslinkage biosynthesis in aortic elastin and collagen
(animals)
** POlHL-13262-07 0016 Arterial wall in atherosclerosis -
Lipids in elastm preparations from atherosclerotic plaques
(human, animals)
** POIHL 13262-07 0023 Arterial wall in atherosclerosis -
Isolation and characterization of soluble elastin
POlHL-13262-07 0025 Arterial wall in atherosclerosis
Phospholipid and cholesterol esters
" P50HL 14218-07 0006 Pulmonary SCOR-Newborn lung
center Biochemical characteristics of the lung in RDS
(human, sheep)
P50HL-15103-07 0014 A/S SCOR -Early natural history of
arteriosclerosis - Biochemistry of atherosclerotic lesions
(monkeys, human, cattle)
M POIHL 15832-06 Chemical-structural predispositions to
lung injury
" POIHL 15832-06 0001 Chemical-structural predispositions
to lung injury - Chemical composition of lung connective
tissue proteins (human, animals)
POlHL-15832-06 0002 Chemical-structural predispositions
to lung injury Connective tissue in lung in development
and repair of injury (human, rats, mice)
P01HL15832 06 0008 Chemical-structural predispositions
to lung injury Interstitial fibrosis -Connective tissue
components in normal and diseased lungs
** POlHL-1 5832-06 0009 Chemical-structural predispositions
to lung mjury Immunology -Enzyme degradation products
of human lung elastin and microfibril
** ROIHL 15965-06 Experimental atherosclerosis and elastin
metabolism (chicks)
M POIHL 16118-06 Study of emphysema
" POIHL 16118 06 0003 Study of emphysema - Degradation
of collagen and elastin (human, hamsters, mice)
** P01HL-I611806 0006 Study of emphysema - Metabolism
of elastin (hamsters)
ROlHL-16206-04 Regression of atherosclerotic plaques
(monkeys, dogs)
ROlHL-17597-05 Role of plasma lipoproteins in
atherosclerosis (swine, human)
** ROIHL 17721-04 Effect of sex hormones on vascular
connective tissue (rats)
ROIHL 1786504 Studies on aging -Effects of sex
hormones (rats, dogs)
P50HL-18318 03 0014 Pathogenesis and complications ot
hypertension Arterial metabolism and atherogenesis (rat,
rabbit)
Icontd)
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level
"Oriented significantly to above subject
M Grant has subprojects describing specific research aspects
See Appendix for investieator's name and grant number
ALB
P50HL18318-03 C015 Pathogenesis and complications of
hypertension - Cultured smooth muscle cells and
microvessel metabolism (mammals)
ROlHL-18441-03 Guidelines for polymers acting as elastin
substitutes
R01HL1862503 Organization of arterial ground substance
(cattle)
POlHL-18645-03 0003 Biology of the artery wall and
atherosclerosis ■ Synthesis of connective tissue proteins by
smooth muscle cells (human, monkeys)
ROlHL-18918-03 Characterization of lung elastins (rat
rabbit, chicken. Rhesus)
ROlHL-18931-02 Lung elastic tissue characteristics
(swine, human)
R01HL1925202 Vascular connective tissue-Role in
atherosclerosis (rabbits)
" R23HL-I9594-01 Tropocollagen and tropoelastin uptake in
lung cells (human)
** POlHL-19717-02 0001 Response of the lung to injury -
Lung elastic tissue (animals)
POlHL-19717.02 0002 Response of the lung to iniury ■
Prolyl hydroxylase, lysyl hydroxylase and lung collagen
biosynthesis (rabbits)
P01HL19717.02 0003 Response of the lung to injury -
pn,m '',°j7,°,'ni'^'5„"' '" ^'"P'lysema (hamsters, rabbits)
POIHL.19717.02 0008 Response of the lung to iniurv -
Experimental models of lung disease
POllHL.19717-02 0012 Response of the lung to iniury ■
Connective tissue biochemistry and enzyme injury of the
lung (hamsters)
" POlHL-1971702 0024 Response of the lung to injury -
Formation of lung alveoli (rats)
POlHL.19717-02 0028 Response of the lung to iniury -
Compensatory growth of the lung following pneumonectomy
(rabbits)
ROlHL-20447-03 Connective tissue and diabetic vascular
disease (human)
ROlHL-20546-02 Chemical analysis of human arterial
elastin
" ROlHL-2076402 Elastin and calcification in pulmonary
and vascular disease ihuman mammals)
" POlHL-20994-02 0009 Dynamics of neutrophil elastase in
the lung - Biosynthesis and degradation of elastin in
emphysema (human, hamsters)
ROlHL-21095-02 Enzymes of M tuberculosis and
obstructive lung disease (human, rodents)
R23HL-2122502 Connective tissue precursor molecules in
the lung (rabbits, hamsters)
ROlHL-2161702 Biochemistry of lung proteoglycans
(rabbits, cattle)
ROlHL-21622-02 Structure and interactions of lung
proteoglycans (cattle)
R01HL-2I64901 Biochemistry of lung proteoglycans
(mammals)
ROlHL-2167301 Pathophysiology of venous changes in
hypertension (rats, rabbits, human, dogs)
ROlHL-21757-01 Elastin structure'-DNA breathing-
Hemoglobin S gelation
ROlHL-21994-01 Structure and development of
regenerating capillaries (rabbits, chick embryo)
" ROlHL-22040-01 Regulation of lysyl-cross-linking in
vascular tissue (rats, turkeys)
** ROlHL-22208-02 Elastin structure, fibrogenesis and
disease (chickens, rabbits)
R23HL-2274501 Vascular mechanics and structure in
hypertension (miniature swine)
ROlHL-2320101 Mechanisms of hypertension (human
rats)
ROlHL-23542-01 Pulmonary vascular smooth muscle cell
dynamics (rat. rabbit)
NOlHR-62910-02 Fibroprotein networks of pulmonary
alveolar wall (human)
ALBUMINOIDS, GELATIN
ROlHL-1801004 Capillary transport of large molecules
(dogs, sheep)
ALBUMINOIDS, KERATOHYALIN
P0IHL06314-17 0048 Immunologic mechanisms in
cardiovascular disease ■ Pathogenesis of glomerulonephritis
(rats, mice)
ALBUMINS
P01HL06285-18 0203 Cardiovascular-respiratory
physiology and biochemistry Pathways of hpid transport
in the blood (animals)
P01HL-0901M5 0015 A research and resource program
in blood - Regulation of synthesis and transport of diverse
proteins in liver (rats)
ROlHL-12740 10 Hypocholesterolemic agents-
Stereochemistry (rats)
ROlHL-13596-07 Clearance of plasma proteins from
alveoli
P01HL-I3738-08 0004 Cardiac assist devices and
artificial hearts - Hematological evaluation of prosthetic
materials (calves)
POlHL-13738-08 0005 Cardiac assist devices and
artificial hearts ■ Development of new materials for
artificial heart and assist devices (sheep dog)
POlHL-15596-05 0017 Coagulation, fibrinolysis,
hemoslasis and hepatitis • Heparin and anlithrombin III
10
PClHL-1674805 0006 Cellular and immunological basis
of pulmonary diseases - Sarcoidosis-Studies with bronchial
lavage (human)
M R01HL16916-04 The role of albumins in lung water
accumulation
ROlHL-16916-04 0001 The role of albumins in lung water
accumulation - Capillary permeability (dogs human)
** ROIHL.16916.04 0002 The role of albumins mlung water
accumulation - Lung water balance -Forces, models and
albumin concentrations (rabbits dogs)
** ROlHL-16916-04 0011 The role of albumins in lung water
accumulation - Whole body distribution and exchange of
albumin (rabbits, human, monkeys)
R01HL-1778I-03 Hypertension, kidney disease and renal
lymph (dogs, rats)
ROIHL-18010-04 Capillary transport of large molecules
(dogs, sheep)
ROIHL- 185 19-03 Albumin, endothelium and
hemocompatibility (human, dog, cattle rabbit)
POlHL-18646-03 0008 Studies basic'to heart
transplantation - Immunophysiology and early detection of
rejection (dogs)
R01HL18736-03 Protein transport through arterial tissue
(rabbits)
R01HL-187G2-03 Post-traumatic pulmonary insufficiency
(dogs)
" P50HL-19185-02 0007 Pulmonary SCOR -Neonatal
respiratory distress syndromes - Sodium bicarbonate and
albumin in resuscitation of preterm infants (human)
ROlHL-19419-03 Cellular interactions with foreign
materials (mammals)
ROlHL-20251-02 A novel approach to nonthrombogenic
polymer surfaces (sheep, cattle)
ROlHL-2145202 Pulmonary capillary filtration in
myocardial ishemia (dogs)
POlHL-22163-01 0001 Surface thrombogenesis-
Mechanisms and prevention - Initial blood protein and
platelet interactions with biomaterials (baboons)
ROlHL-22911-01 Mechanism of clearance of lung edema
fluid (dogs)
ROlHL-22924-01 The airway mucosal barrier (guinea pigs)
ROIHL 22946-01 Prostaglandins, platelet aggregation and
vasoactivity (human, rats, rabbits)
ALBUMINS, CONALBUMIN
ROlHL-18619-03 Transferrin iron binding and transport
properties (chicken, rabbit, human)
ALBUMINS, SERUM ALBUMIN
ROlHL-02751-21 Function and metabolism of serum
albumin (mammals, fish, amphibians)
" POlHL-06370-17 0004 Cardiopulmonary and renal
pathology research center - Lymphocytes in graft rejection
and immune surveillance (human)
P60HL-15160-07 0008 Center for sickle cell disease -
Isocyanate derivatives and hemoglobin S association
(human, rat)
ROlHL-15698-12 Factors affecting the action of
anticoagulants (rats, human)
ROIHL- 164 19-03 Arterial uptake of lipoprotein-Kinetic
analysis (rabbits)
P60HL-1 7265-04 0001 Community blood resource center
support - Demonstration and evaluation
ROlHL-17623-05 Initial events in thrombus formation on
surfaces (human, rats)
POlHL-18576-03 0001 Thrombosis research program
project - Platelet damage from physical forces and
artificial surfaces (human)
ROlHL-18619-03 Transferrin iron binding and transport
properties (chicken, rabbit, human)
ROlHL-18731-02 RES stimulating materials in
experimental shock (dogs)
ROlHL-18887-03 Hypolipidemic drugs-Effects on FFA-
albumin association (human, cattle)
ROlHL-20313-02 Surface-induced thrombosis -Modification
of albumin variants (human, goat)
ALBUMINS, SERUM ALBUMIN BOVINE
P50HL19185-02 0007 Pulmonary SCOR -Neonatal
respiratory distress syndromes ■ Sodium bicarbonate and
albumin in resuscitation of preterm infants (human)
ALCOHOL CONSUMPTION
SEE ALCOHOLISM - DRINKING, ALCOHOL CONSUMPTION
ALCOHOL RESEARCH REVIEW COMMIHEE
ROlHL-2036903 The effect of alcohol on the heart (rats)
ALCOHOLISM
SEE ALCOHOLISM - DRINKING, ALCOHOLISM
ALCOHOLISM - DRINKING, ALCOHOL
CONSUMPTION
ROlHL-15308-07 Assays lor peptides of lipoproteins
(human)
ROlHL-1877604 Prevention of acute and fatal
cardiovascular disease (human)
ROlHL-19839-09 Factors in youth predisposing to chronic
diseases (former college students)
ROlHL-19984-02 Blood pressure and immunogenetic
factors in the young (human)
ROlHL-20179-02 Epidemiology of sudden cardiac death
among women
••nn»nL'°"""f ""^''''"•11 OR "vers only general proiects «hich preclude indexing
Oriented significantly to above subject >. ""<: ncue.iiig
ALD
R01HL-2197I.01 Atherosclerotic disease and risk factors
in twins (human)
ROlHL-22607-01 Role of apolipoprotein E in lipoprotein
metabolism (human)
N01HV^62955-04 Data collection in clinical pathology and
morbid anatomy (men)
ALCOHOLISM - DRINKING, ALCOHOLISM
POlHL-08214-15 0006 Chemical and biological properties
of lipids ■ Analysis and properties of lipids
ROlHL-09562-14 Cardiac protein synthesis, overload
alcohol and anoxia (guinea pigs)
** ROlHL-20369-03 The effect of alcohol on the heart (rats)
ROlHL-23945-06 Pathologic effects on cells of modified
lipoproteins (rats, human)
ALCOHOLS
SEE ALSO BILE ALCOHOLS
ROlHL-13989-05 Role of water in respiratiory protein
structure
ALCOHOLS, BUTANOL
ROlHL-13567-06 Ion transport across cell membranes
(human)
ALCOHOLS, DIOLS
POlHL-08214-15 0006 Chemical and biological properties
of lipids ■ Analysis and properties of lipids
POlHL-08214 15 0025 Chemical and biological properties
of lipids - Biosynthesis and biological functions of
plasmalogen (cattle)
** POIHL 08214 15 0027 Chemical and biological properties
of lipids - Biological functions diol lipids (swine rats
plants)
POlHL-0821415 0040 Chemical and biological properties
of lipids ■ Nuclear magnetic resonance studies of lipids
ALCOHOLS, DIOLS, ETHYLENE GLYCOL
ROlHL-20219-02 Ciyopreservation of the isolated heart
(rats)
ALCOHOLS, DIOLS, PROPYLENE GLYCOL
ROlHL-19722-03 Aerosol growth in the respiratory system
(models)
ALCOHOLS, ENOLS
ROlHL-22612 01 Stabilized prostacyclins to treat vascular
disease
ALCOHOLS, ETHANOL
" POlHL-0889914 0027 Tolerance to respiratory gases in
health and disease - Effects of high oxygen pressures on
ethanol metabolism (human)
POlHL-0889914 0061 Tolerance to respiratory gases in
health and disease Hepatic oxygenation and secretory
functions (rats, dogs)
ROlHL-09562-14 Cardiac protein synthesis, overload,
alcohol and anoxia (guinea pigs)
P01HL10539-12 0068 Pathophysiology of circulation ■
Acute and chronic cardiomyopathies (mice, dogs, hamsters
human)
POlHL-11310 12 0092 Mechanisms of cardiovascular
disease - Exercise electrophysiology (human)
P01HL1237310 0005 Cardiopulmonary physiology and
pathophysiology - Characterization of fetal and neonatal
myocardium (human, cats)
R01HL14706-07 Fetal hearts in organ culture (mice)
POlHL-14985-07 0009 Adaptation to hypoxia ■ Influence
of chemosensitivity on control of breathing during sleep
(human, dogs)
ROIHL 17571-03 Study of membrane permeability by NMR
relaxation (human)
R01HL18607 03 Metabolic and drug studies on
experimental fat embolism (mice)
ROlHL-20369-03 The effect of alcohol on the heart (rats)
ALCOHOLS, METHANOL
ROIHL 19491-03 Mechanism of iron storage and
mobilization by ferritin (horse)
ALCOHOLS, PROPANOLS
SEE ALSO NAPHTHYUMINES, PROPRANOLOL
P01HL06835-17 0057 Cardiovascular disease - Studies
on cardiac hypertrophy
ALDEHYDE LYASES
SEE ALDOLASES
ALDEHYDES
SEE ALSO DICARBOXYLIC ALDEHYDES, MALONALDEHYDE
ROIHL-1824503 Transition state analog inhibitors of
thrombin (human, cattle)
ROlHL-23115-01 Regulation of active sodium transport
(frogs, rats)
ALDEHYDES, ACETALDEHYDE
ROlHL-09562 14 Cardiac protein synthesis, overload,
alcohol and anoxia (guinea pigs)
ROlHL-18554-03 Taurine metabolism in mammalian heart
(rodents, cattle, swine)
ROlHL-2036903 The effect of alcohol on the heart (rats)
ALDEHYDES, FORMALDEHYDE
P50HL14230-07 0097 A/S SCOR-Lipids, atherosclerosis
and thrombosis ■ Studies of circulating platelet aggregates
(human)
at the specific level.
M Grant has subprojecls describing specific research aspects
See Appendix for investigator's name and grant number
(contdl
AID
ALDOLASIS
NOIHI l'9?6 18 ChtmKil aitnts and hiiart (lycotytlc
•nmnes (shnp)
ALDOSTERONE
Sn AORtNAl CORIEX HORMONES, ALDOSIERONt
ALDOSTERONE INHIBITORS
SEE ADRENAL CORTEX HORMONIS. AIDOSIERONE
INHIBITORS
ALDOSTERONE STIMULATING FACTOR ANT PIT
SEI PITUIIARY OIENCEPHAION HORMONES. ACTH
ALDOSTERONE STIMULATING FACTORS
SEE ADRENAL CORTEX HORMONES. ALDOSTERONE
STIMULATING FACTORS
ALDOSTERONISM
SEE ADRENAL GLANDS DISORDERS. HYPERAIOOSTERONISM
ALERTNESS-VIGILANCE
SEE PSYCHIC ACTIVITY LEVEL. ATTENTION
AUXIN
SEE IMMUNOLOGY. COMPLEMENT
ALFALFA
SEE PLANTS. ANGIOSPERMS. LEGUMES, ALFALFA*
AUESTERASE
SEE CARBOXYLIC ESTER HYDROLASES. CARBOXYLESTERASE
ALIMENTARY TRACT
SEE GASTROINTESTINAL SYSTEM (GENERAL)
ALKAU METALS
SEE METALS. ALKALI METALS
ALKAUES
SEE ACIDS BASES. ALKALIES
ALKALINE EARTH METALS
SEE METALS, ALKALINE EARTH METALS
ALKALINE PHOSPHATASE
SEE PHOSPHOMONOESTERASES, ALKALINE PHOSPHATASE
ALKALOIDS
SEE ALSO PLANTS EXTRACTS, MEDICINAL PLANTS
SEE ALSO PURINES. XANTHINES. CAFFEINE
SEE ALSO PURINES. XANTHINES, THEOPHYLLINE
SEE ALSO PYRIDINAMIDES, NICOTINAMIDE
SEE ALSO PYRIDINE CARBOXYLIC ACIDS, NICOTINIC ACID
SEE ALSO QUINOLINES
SEE ALSO QUINUCLIDINES
SEE ALSO TOXICOLOGY, ANIMAL POISONS, BATRACHOTOXIN
SEE ALSO TOXICOLOGY, ANIMAL POISONS, TETRODOTOXIN
SEE ALSO TOXICOLOGY, PROTOZOAL TOXINS, SAXITOXIN
** ROlHL-07502 13 Phytochemistty of the genus fhalictrum
(dogs, plants)
ROlHL-12971-15
ROlHL-1647105
Indole alkaloids
RClHL-20579-02
alkaloids
ROlHL-22783-01
Reactions of alkoloids and their analogs
Cardioactive alloyohimbines and related
Synthesis of therapeutically important
Hemodynamic induction of intimal
fibromuscular lesion
ALKALOIDS, ACONINE TYPE
ROlHL-21670-01 Antiarrhythmic studies on 2substituted
aminoindenes (dogs)
ALKALOIDS, BERBINES
ROlHL-1297115 Reactions of alkoloids and their analogs
ALKALOIDS, CANNABIS
P01HL14985-07 0004 Adaptation to hypoxia - Control of
breathing in respiratory failure (human, dogs)
POlHL-14985-07 0009 Adaptation to hypoxia - Influence
of chemosensitivity on control of breathing during sleep
(human, dogs)
ALKALOIDS, COLCHICINE
SEE ALSO ALKALOIDS, OEMECOLCINE
POlHL-06370-17 0004 Cardiopulmonary and renal
pathology research center - Lymphocytes in graft rejection
and immune surveillance (human)
R01HL13909-27 Physiochemistry and Immunol )gy of
macromolecules
ROlHL-16437-05 Drug treatment of atherosclerosis
(rabbits, monkeys)
ROlHL-20643-02 Analysis of heart cell contraction (rats)
ALKALOIDS, DEMECOLCINE
R01HL15512-06 Drug treatment of stenosing primate
atherosclerosis (rabbits, monkeys)
ALKALOIDS, ERGOT
ROlHL-18590-03 Cerebral blood flow after cardiac arrest
(dogs, monkeys)
ROlHL-20579-02 Synthesis of therapeutically important
alkaloids
ALKALOIDS, ERGOT, METHYSERGIDE
ROlHL-22005-01 Intermittent retropcrfusion of ischemic
myocardium (dogs)
1 1
ALKALOIDS, MONOCROTALINE
POIMI 0H80i I'j 0048 Regulation ol vcniilatlon ind
puliiionjiy ciiculntion Pefm«»billly ol ilveolo Ctpllliry
m«mbnn« in normal pulmonary hyperteujivf lung
ROIHL 19394 03 Biochnmislry and lejulalion ol taurine in
the heart (lats. guincn pigj. cats)
ALKALOIDS, MORPHINES
POIHI 08899 14 0030 Tolerance to respiratory gaies In
health and disease Dynamic characleiisticj ol respiratory
control components (human, cats)
POIHI 12/38 10 0042 Physiologic pharmacology and its
clinical applications Centrogenic cardiac arrhythmias
(cats)
ROIHL 14092 07 Homeostatic regulation ol plasma choline
(rats. dogs, chickens)
POIHL 1498507 0003 Adaptation to hypoxia Hypoxia
and oxygen transport (human, dogs)
POIHL 1498507 0009 Adaptation to hypoxia Influence
of chemosensitivity on control of breathing during sleep
(human, dogs)
ROIHL 1602205 Determinants of the ventilatory response
to hypoxia (goats, cats)
P50HL1766504 0026 Study of ischemic heart disease
Anesthesia Myocardial ischemia and hemodynamics in
coronary disease (human)
*• ROIHL 17954-03 Narcotics and the circulation (human,
dogs, pigs, monkeys)
ROlHL-2037102 Intravascular redistribution of blood
volume (dogs)
ALKALOIDS, MORPHINES, NALOXONE
R01HL1795403 Narcotics and the circulation (human,
dogs, pigs, monkeys)
ALKALOIDS, RAUWOIFIA TYPE, AJMALINE
ROlHL-21672-01 Antiarrhythmic drug action on VMAZ of
cardiac cells
ALKALOIDS, RAUWOIFIA TYPE, RAUWOLFIA
SEE ALSO ALKALOIDS, RAUWOLFIA TYPE, AJMALINE
SEE ALSO ALKALOIDS, RAUWOLFIA TYPE, RESERPINE
SEE ALSO ALKALOIDS. RAUWOLFIA TYPE, YOHIMBINE
R01HL107 11-12 Cooperative study of treatment of
hypertension (human)
ALKALOIDS, RAUWOLFIA TYPE, RESERPINE
R01HL1O71112 Cooperative study of treatment of
hypertension (human)
ROlHL-147 13-06 Hypothermia and the heart (bats, guinea
pigs)
ROIHL-15047-06 Digital computer analysis of the
electrocardiogram (human)
ROlHL-16471-05 Cardioactive alloyohimbines and related
indole alkaloids
ROlHL-17909-04 Drug treatment of vascular scleroprotein
defects (human, turkeys)
P01HL18974-03 0011 Experimental neurogenic
hypertension program - Biochemistry and regulation of
brain tryptophane hydroxylase (rats)
R23HL-19573-01 Studies on pulmonary serotonin (mice)
ROIHL 20579-02 Synthesis of therapeutically important
alkaloids
ROlHL-22563-02 Prostaglandins, the kidney and
hypertension (rats)
ROlHL-22573-01 Treatment of post surgical
vasoconstriction (dogs, monkeys, human, rats)
** NOlHV-62900-00 Study of breast cancer and reserpine use
(human)
ALKALOIDS, RAUWOLFIA TYPE, YOHIMBINE
ROlHL-08359-14 Morphopharmacology of vascular
adrenergic transmission (rabbits, rats)
*• ROlHL-16471-05 Cardioactive alloyohimbines and related
indole alkaloids
ALKALOIDS, RYANIA
R23HL-21325-02 Sarcomere kinematics in cardiac
contraction (rats, rabbits)
ALKALOIDS, SENECIO
ROlHL-19394-03 Biochemistry and regulation of taurine in
the heart (rats, guinea pigs, cats)
ALKALOIDS, VINBLASTINE
ROlHL-20643-02 Analysis of heart cell contraction (rats)
ALKALOIDS, VINCA
SEE ALSO ALKALOIDS, VINBLASTINE
ROlHL-16437-05 Drug treatment of atherosclerosis
(rabbits, monkeys)
ALKALOSIS
SEE BODY FLUID BALANCE, ACID-BASE, ALKALOSIS
ALKANES
POlHL-12157-11 0038 Functions and mechanisms of cell
membrane ion transport - Mechanisms and interactions of
gases and ions with bilayer membranes (human)
ALKANES, METHANE
ROlHL-17702-04 Electro-optical dyes as probes of heart
excitability
ROlHL-1974603 Proliferation and differentiation of
alveolar macrophages (mice, hamsters)
ALL
ALKENES, ISOPRENOIDS
Sff AISOPIASIIC, HDBHIR
Sff ALSO IfHPTNf".. CAKOIINOID',
Sff Also VITAMIN A
Sff Also VITAMIN K
ROIHI 16101 0') Piolein lipid inleuchon (batlMli,
modeli)
ROIHL 19011 03 Smooth muscle cell membrane
glycoprotein biosynthesis (caltle)
AlKYL (GROUPS)
POIHI 0*214 15 0025 Chemical and biological properliei
of lipids Biosynthesis and biological functions ol
plasmalogen (cattle)
POIHI 08214 15 00?/ Chemical and biological properties
of lipids Biological functions diol lipids (swine, rats,
plants)
POIHL 15195 04 0001 Program project in biological
materials Design and synthesis
AlKYL (GROUPS), ALKYLATION-DEALKYLATION
POIHL 185/7 03 0004 Lipoproteins Cell surtace
interactions Analysis and chemical modification of
proteins in lipid transport (human, dogs)
ROIHL 19654 03 Biochemical pharmacological evaluation
of lung cells (rabbits)
ROIHL 22471 01 Biochemistry of prothrombin quick
(human)
ROIHL 22845 01 Response of cardiac myosin to
hypertrophic stress (rabbits)
AlKYL (GROUPS), DEMETHYLATION
ROlHL-19654 03 Biochemical pharmacological evaluation
of lung cells (rabbits)
AlKYl (GROUPS), METHYLATION
POIHL 11351 12 0004 Cellular and molecular
mechanisms of myocardial function Molecular
mechanisms of contractile function and differentiation
(animals)
R01HL12647-08 Inactivation of norepinephrine in vascular
tissue
POlHL-13851 16 Cyclotron produced isotopes in biology
and medicine (human, animals)
P01HL18577-03 0004 Lipoproteins-Cell surface
interactions • Analysis and chemical modification of
proteins in lipid transport (human, dogs)
ALKYLATING AGENTS
SEE ALSO HALOALKYLAMINES, NITROGEN MUSTARDS
POlHL-2101602 0002 Sickle cell anemia and other
hemoglobinopathies - Molecular events proceeding gelation
of Hb S
POlHL-21016-02 0004
hemoglobinopathies
** POlHL-21016-02 0010
hemoglobinopathies
agents
** POlHL-21016-02 0011
hemoglobinopathies
agents (hamsters)
POlHL-21016-02 0013
hemoglobinopathies
cell treated with anti-sickling agents (rats)
ALKYLATION
SEE ALKYL (GROUPS), ALKYLATION-DEALKYLATION
ALKYL NITRILES
SEE CYANIDES, ALKYL NITRILES
ALKYNES
ROlHL-20996-02 Structural and reactivity of iron and
cobalt complexes
ALLELES
SEE GENETICS, GENES. ALLELES
ALLERGENS
SEE HYPERSENSITIVITY, ALLERGENS
ALLERGENS AIRBORNE
SEE HYPERSENSITIVITY, ALLERGENS AIRBORNE
ALLERGIC ALVEOLITIS
SEE RESPIRATORY DISORDERS, PNEUMONITIS ALLERGIC
INTERSTITIAL
AUERGIC INTERSTITIAL PNEUMONITIS
SEE RESPIRATORY DISORDERS. PNEUMONITIS ALLERGIC
INTERSTITIAL
ALLERGY
SEE HYPERSENSITIVITY (GENERAL)
ALLERGY AND IMMUNOLOGY STUDY SECTION
** ROlHL-03919 20 The cell suface of streptococci (rats.
human)
** ROlHL-08399-15 Platelet injury in infections and allergic
diseases (human)
** ROlHL-10608 12 Digoxin-specific antibodies (human)
** ROlHL-18526-03 Kinins and the human lung
** ROlHL-20125-02 Cyclic nucleotides and alveolar
macrophage activation (rabbits)
** ROlHL-20394-03 Complement activation by heart
subcellular membranes (human, dog)
(contdl
Sickle cell anemia and other
Kinetics of sickling
Sickle cell anemia and other
• Alkylureas as potential anti-sickling
Sickle cell anemia and other
- Metabolic effects of anti-sickling
Sickle cell anemia and other
■ Microcirculatory response to sickle
•Excludes routine raethodotogy OR covers only general projects which preclude
"Oriented significantly to above subject
indexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
ALL
** ROlHL-2053309 Pathogenesis of rheumatic fever (human
rabbits)
*• ROlHL-21874.01 SRS-A-lts biosynthesis and action
ROlHL-23586-06 Pharmacologic control of hypersensitivitv
phenomena (human)
ALLIED HEALTH PERSONNEL
SEE HEALTH SCIENCES PROFESSIONS, HEALTH (CARE)
PERSONNEL ALLIED
ALLIED HEALTH PERSONNEL EDUCATION
SEE EDUCATION, HEALTH OCCUPATIONS, ALLIED
ALLIUM
SEE PLANTS, ANGIOSPERMS, ALLIUM*
ALLOANTIBODIES
SEE TISSUE COMPATIBILITYTRANSPUNT, ISOALLOANTIBOOIES
ALLOANTIGENS
SEE TISSUE COMPATIBILITY-TRANSPUNT, ISOALLOANTIGENS
ALLOANTISERA
SEE IMMUNITY IMMUNOSUPPRESSION, ALLOANTISERA
ALLOGENIC INHIBITION, ANTISERA
SEE IMMUNITY, IMMUNOSUPPRESSION, ALLOANTISERA
ALLOGRAFT
SEE TISSUE COMPATIBILITY TRANSPLANT, TRANSPLANTATION
HOMOLOGOUS
ALLOIMMUNITY
SEE TISSUE COMPATIBILITY TRANSPLANT, ISOALLOIMMUNITY
ALLOPURINOL
SEE DIAZ0L0DIA2INES, PYRAZOLOPYRIMIDINES, ALLOPURINOL
ALLOSTERIC SITES
SEE CHEMICAL REACTION SITES, ALLOSTERIC SITES
ALLOXAN
SEE PYRIMIDINES, ALLOXAN
ALLOYS
SEE METALS, ALLOYS
ALLYLAMINES
SEE AMINES, ALLYLAMINES
ALOUATTA
SEE MAMMALS, PRIMATES, MONKEYS AND APES
(ANTHROPOIDS, NON-HUMAN), NEW WORLD MONKEYS
(PLATYRHINES)*
ALPHA GLOBUIIN(S)
SEE GLOBULINS, ALPHA GLOBULINS
ALPHA 2-AP-GLOBULIN
SEE IMMUNOLOGY, ACUTE PHASE PROTEINS
ALPHA RECEPTORS
SEE NEUROTRANSMITTERS RECEPTORS, ADRENERGIC
RECEPTORS, ALPHA RECEPTORS
ALPHA WAVE (BIOFEEDBACK) CONDITIONING
SEE PSYCHOLOGY, CONDITIONING, AUTOGENIC AND INTERNAL
CONTROL
ALPHA WAVE (TROPHOTROPIC) STATE
SEE PSYCHIC ACTIVITY LEVEL, TROPHOTROPIC STATE
ALPRENOLOL
SEE AMINO ALCOHOLS, PROPANOLS, ALPRENOLOL
ALTERNATION OF GENERATIONS
SEE BIOLOGY, LIFE CYCLE
ALTITUDE
SEE ENVIRONMENT, ALTITUDE
ALTITUDE STRESS
SEE ENVIRONMENT, STRESS, ALTITUDE
ALVEOLAR MACROPHAGES
SEE RESPIRATORY SYSTEM, ALVEOUR MACROPHAGES
ALVEOLITIS ALLERGIC
SEE RESPIRATORY DISORDERS, PNEUMONITIS ALLERGIC
INTERSTITIAL
ALVEOLUS, LUNG
SEE RESPIRATORY SYSTEM, LUNG ALVEOLUS
AMERICAN INDIANS
SEE SOCIAL GROUPS, ETHNIC, AMERICAN INDIANS
AMERICAN TYPE CULTURE COLLECTION
SEE TISSUE (CELL) CULTURE, CELL CULTURE COLLECTIONS
BANKS AND REGISTRIES
AMIDATION
SEE AMIDES, AMIDATION
AMIDES
SEE ALSO PHOSPHORAMIDES
SEE ALSO SULFONAMIDES
ROlHL-22780-01 Factors modifying the reaction properties
of HgS (human)
12
AMIDES, ACETAMIDES
POlHL-1559605 0008 Coagulation, fibrinolysis,
hemostasis and hepatitis - Structural studies and
fractionation of antihemophilic factor (human)
R01HL17571-03 Study
relaxation (human)
POlHL.20993-02 0004 Population dynamics of arterial
cells in atherogenesis ■ Modifications of cholesterol balance
related to arterial cell divisions (swine)
AMIDES, AMIDATION
R01HL14820-07 Factors affecting physiology of biological
Pfini!r,''no«fn*,''nZ"* "' membrane permeability by NMR
P60HL-20985.01 0006 Northern California sickle cell
center ■ Antisickling properties of imidoeslers (human, rats)
R01HL-2164401 Fibronecfin and related glycoproteins
(human, rodents)
AMIDES, UREA
SEE ALSO THIOUREA
ROlHL-02334-23 Micropuncture study of kidney function
(rats, animals)
P01HL-) 13 10-12 0080 Mechanisms of cardiovascular
disease - Metabolism of 'he hyperlrophied myocardium
(human)
P01HL1441407 0014 Environmental influences on
cardiorespiratory and cellular functions Temperature and
acid-base status in tissues, cells, and subcellular system
POIHL-15596-05 0008 Coagulation, fibrinolysis,
hemostasis and hepatitis - Structural studies and
fractionation of antihemophilic factor (human)
R0iHL1637504 Investigation of hemoglobin S properties
(human)
ROlHL-17571-03 Study of membrane permeability by NMR
relaxation (human)
ROlHL-17847-04 Cardiovascular and renal functions of
marmots
P50HL.191 53-02 0005 SCOR-Pulmonary edemas-Eitology
pathogenesis - Lung vascular permeability measured by
indicator dilution methods (sheep)
POlHL-21016-02 0002 Sickle cell anemia and other
hemoglobinopathies - Molecular events proceeding gelation
of Hb S
P01HL21016-02 0004 Sickle cell anemia and other
hemoglobinopathies ■ Kinetics of sickling
■?* POlHL-2101602 0010 Sickle cell anemia and other
hemoglobinopathies ■ Alkylureas as potential anti-sickling
agents
POlHL-210 16-02 0013 Sickle cell anemia and other
hemoglobinopathies - Microcirculatory response to sickle
cell treated with anti-sickling agents (rats)
ROlHL-22924-01 The airway mucosal barrier (guinea pigs)
AMIDINOTRANSFERASES
•SSfl™"*'"! '"'^.!'°''°"'» 0" '='"«'S only general projects which preclude indexing
Uriented significantly to above subject.
ROlHL-201 06-02 Coupling of platelet contractile proteins
to fibrin (human)
AMILORIDE
SEE PYRAZINAMIDES, AMILORIDE
AMINE HORMONES
SEE CHOLINE, ACETYLCHOLINE
SEE PHENYLALKYUMINES, CATECHOLAMINES, EPINEPHRINE
SEE PHENYULKYLAMINES, CATECHOLAMINES
NOREPINEPHRINE
SEE THYROID HORMONES, THYROXINE
SEE THYRONINE, TRIIODOTHYRONINE
AMINE OXIDASE
SEE OXIDOREDUCTASES, AMINE OXIDASE (FUVIN
CONTAINING)
AMINE OXIDASE (FLAVIN CONTAINING)
SEE OXIDOREDUCTASES, AMINE OXIDASE (FLAVIN
CONTAINING)
AMINE OXIDASE (PYRIDOXAL CONTAINING)
SEE OXIDOREDUCTASES, AMINE OXIDASE (PYRIDOXAL-
CONTAINING)
AMINE OXIDASE INHIBITORS
SEE ENZYME INHIBITORS, MONOAMINE OXIDASE INHIBITORS
AMINES
SEE ALSO AMMONIUM QUATERNARY
POlHL-15832-06 0007 Chemical-structural predispositions
to lung injury - Inactivation of vasoactive agents by the
lung (human, rats, cats, dogs)
ROlHL-20622-02 Pulmonary uptake and accumulation of
drugs (rabbits, rats)
AMINES, ALLYLAMINES
R23HL-21327-02 Molecular mechanisms of chemical
myocardiopathies (rats)
AMINES, BIOGENIC, NEURAL
SEE NEUROTRANSMinERS (GENERAL)
AMINES, DIAMINES
R0IHL-20079-02 0001 Thromboresistant material - Active
and passive thromboresistant surfaces
AMINES, HYDROXYLAMINES, HYDROXAMIC
ACIDS
R01HL-18679-04 Synthetic protease inhibitors
at the specific level.
AMI
R01HL-200 16-03 Chelator development for thalassemia
(human, mice, rats, dogs, monkeys)
AMINES, POLYAMINES
R01HL-167i4-05 Endothelial cell communication in
homeostasis (human, mammals)
" P50HL-19157-02 0009 Studies in cystic fibrosis and
bronchiolitis - Polyamine metabolism in cystic fibrosis
(human, rat)
P01HL-20984-02 0006 Cellular mechanisms in cardiac
hypertrophy • Early biochemical aspects of cardiac
hypertrophy (rats)
ROlHL-2262301 Polyamines cellular mediators of
atherogenesis (human)
ROlHL-22883-01 Lung epithelial cell interactions in vitro
AMINES, PUTRESCINE
POIHL 13851-16 Cyclotron produced isotopes in biology
and medicine (human, animals)
P50HL-19157-02 0009 Studies in cystic fibrosis and
bronchiolitis Polyamine metabolism in cystic fibrosis
(human, rat)
AMINES, SPERMIDINE
P50HL-19157-02 0009 Studies in cystic fibrosis and
bronchiolitis - Polyamine metabolism m cystic fibrosis
(human, rat)
AMINES, SPERMINE
P50HL-19157-02 0009 Studies in cystic fibrosis and
bronchiolitis - Polyamine metabolism in cystic fibrosis
(human, rat)
AMINO ACID ANALYZER
SEE PHYSICAL SEPARATION. CHROMATOGRAPHY, AMINO ACID
ANALYZER*
AMINO ACID DECARBOXYLASES
SEE DECARBOXYLASES, AMINO ACID DECARBOXYLASES
AMINOACIOOPATHIES, ACQUIRED
P01HL18645-03 0006 Biology of the artery wall and
atherosclerosis - The platelet and atherosclerosis (monkeys
baboons) '
AMINOACIOOPATHIES, INBORN
SEE METABOLIC DISORDERS INBORN, AMINOACIOOPATHIES
AMINO ACID OXIDASES
SEE OXIDOREDUCTASES. AMINO ACID OXIDASES
AMINO ACIDS
SEE ALSO AMINO ACYL TRNA
SEE ALSO AMINOSULFONIC ACIDS
SEE ALSO CARBAMATES
SEE ALSO CYCLIC AMINO ACIDS
SEE ALSO NUTRITION. DIETARY CONSTITUENTS DIETARY
AMINO ACIDS
SEE ALSO OXAMATES
R01HL-01974-24 Ion-pump in the erythrocyte (rabbits
guinea pigs)
P01HL-07896-15 0032 Environmental biomedical research
program ■ Fluorometry study of brain exposed to hyperbaric
oxygen (dogs, cats)
ROlHL-13193-09 Pathophysiology of post-traumatic and
shock states (rodents, dogs)
POlHL-15195-04 0004 Program project in biological
materials ■ Biological evaluation and surface interaction
studies (dogs)
POlHL-15832-06 0001 Chemical structural predispositions
to lung injury - Chemical composition of lung connective
tissue proteins (human, animals)
R0IHL-16553-05 Diagnosis of myocardial infarction by
radioisotopes (mice, rats, goats)
ROIHL- 17930-03 Platelet membrane function-Assessment
and application (animals)
ROlHL-18593-03 Characterization of heart valve collagen
(human, pig)
R01HL-20344-02 Regulation of protein turnover in lung
tissue (rats)
ROlHL-21140-01 Studies of pulmonay alveolar
macrophage function (rabbits)
ROlHL-21970-01 Myofibrillar assembly and breakdown in
cardiac muscle (rats)
R01HL-22387-01 Metalloenzymes and disease
ROlHL-22780-01 Factors modifying the reaction properties
of HgS (human)
AMINO ACIDS, ALANINE
POlHL-15195-04 0001 Program project in biological
materials - Design and synthesis
P50HL-17651-04 0041 Ischemic heart disease specialized
center of research - Biochemical indices of ischemic injury
(guinea pig)
ROlHL-21381-02 Amino acid metabolism in normal and
hypoxic myocardium (rabbits)
AMINO ACIDS, GAMMA-AMINOBUTYRIC ACID
ROlHL-05883-18 0001 Reflex control of resistance and
capacitance vessels - Naturally occurring vasoactive
substances and the vascular neuroeffectors (dog)
R01HL-I3187-09 Central neural control of cardiovascular
function (cats)
POlHL-16878-05 0004 Control of ventilation in health
and disease - Neurotransmitters in the respiratory system
(cats)
M Grant has subproierts describing specific research aspects
See Appendix for investigator's name and grant number.
(contdl
AMI
KOIHl 1/90/04 Bidin lenuldlioii ot ciididc jiihylhnua
(pi|S. Cils, rjts)
ROIHI ??7I50I N«ut«l inlegiation ol lh» ctcdiowasculat
it'llews (dogs))
AMINO ACIDS, AlPHA-AMINOISOBUTYRIC ACID
St[ ALSO CYCIIC AMINO ACIDS, OOPA AlPHA Ml IHYl DOI'A
ROIHI ?23M 01 Alpha adreneigic elleils on heart
metabolism (lats)
AMINO ACIDS, BRANCHED CHAIN AMINO
ACIDS
PbOHl l/bBI) 04 00:9 Study of ischemic heart disease
Myocardial ptolein synthesis and degradation in low oiygen
stales (Mhbit, dog)
ROIHL 18;'S8 04 Regulation ol protein degradation in
heart (rats)
ROIHL 20388 03 Regulation ot protein turnover in diabetic
heart (rat)
ROIHL 21381 02 Ammo acid metabolism in normal and
hypoxic myocardium (rabbits)
AMINO ACIDS, N-CARBAMYl AMINO ACIDS
P60HL 151600? 0008 Center (or sickle cell disease
Isocyanate derivatives and hemoglobin S association
(human, rat)
AMINO ACIDS, CREATINE
ROIHI 2320501 Contraction ot pulmonary vascular
smooth muscle (cat)
AMINO ACIDS, CREATINE PHOSPHATE
*• P01HL06312 17 0034 Surgical cardiology Metabolic
factors in cardiac function-Creatine phosphate depletion
(animals)
POIHL 1135112 0021 Cellular and molecular
mechanisms of myocardial function • Muscle energetics
(frogs)
P01HL1135M2 0022 Cellular and molecular
mechanisms of myocardial function • Energetic sequelae of
shortening -Myothermal and biochemical (frogs)
POIHL 11351 12 0023 Cellular and molecular
mechanisms of myocardial function - Energetics ol
mammalian muscle (rats)
POIHL 1583506 0011 Study of muscles related to heart
disease - Energetics and mechanism of muscle contraction
(frogs, rabbits)
P50HL 1767004 0023 Study of ischemic heart disease -
Energy metabolism in acute myocardial ischemic injury
(dogs)
ROIHL 20658-01 Myocardial energy transport Creative
kinase (human, cattle, dog)
ROlHL-21312-01 Sarcomere mechanics in disrupted
ventricular muscle (guinea pigs)
R23HL-21842 01 Control of sugar entry in normal and
diabetic heart (rats)
ROlHL-22290-01 Cardiac energy metabolism and protein
synthesis (mice)
AMINO ACIDS, CREATININE
R01HL40612-13 0018 Humoral factors in heart failure
and hypertension ■ The pathogenesis of experimental renal
hypertension (dogs, rabbits, rats)
AMINO ACIDS, DIETARY
SEE NUTRITION, DIETARY CONSTITUENTS, DIETARY AMINO
ACIDS
AMINO ACIDS, ETHYLENEDIAMINO ACIDS, EDTA
P50HL-I4230-07 0097 A/S SCOR- Lipids, atherosclerosis
and thrombosis ■ Studies of circulating platelet aggregates
(human)
R01HL16010-16
(frogs)
ROlHL-16674-05
(bullfrogs, rats)
AMINO ACIDS, GLYCINE
SEE ALSO AMINO ACIDS, SARCOSINE
SEE ALSO PEPTIDES, GLUTATHIONE
ROlHL-02558-22 Structure-function relationships in the
heme proteins (human, cattle)
ROlHL-13187-09 Central neural control of cardiovascular
function (cats)
** ROIHL-13256-08 Ammo acid transport by red cell
membranes (pigeons)
POlHL-16878-05 0004 Control of ventilation in health
and disease - Neurotransmitters in the respiratory system
(cats)
ROlHL-21303-02 Collagen synthesis by cultured human
vascular cells
AMINO ACIDS, HIPPURATES, P-
AMINOHIPPURATE
ROlHL-02835-21 Renal transport carrier for organic
compounds (dogs, rats)
AMINO ACIDS, HOMOSERINE
R01HL-18818-04 Stereochemical mechanism of sickling of
hemoglobin S (human)
AMINO ACIDS, LEUCINE
POlHL-15195-04 0001 Program project in biological
materials - Design and synthesis
Cellular basis of cardiac contractility
Airborne metals and lung permeability
13
POIHl 19742 02 0001 Study ot vascular \moolh muicle
(nergy metiibolism and protein turnover in va\culai \moolh
muscle (rals)
AMINO ACIDS, IIPOAMINO ACIDS
Ml CMOSI'IIOIIPIDS PHOSI'IKICIYCIHIIUS, PHOSPHATIOYl
SiKINt
AMINO ACIDS, PHOSPHOSERINE
POIHL 1215/ II 003H (unilions and mechanisms of cell
membrane ion transport Mechanisms and inleraclions ol
gases and ions with bilayer membranes (human)
AMINO ACIDS, SARCOSINE
•• POIHI 06835 I / 0056 Cardiovascular disease
Angiotensin analogs Sarcosine on arterial pressure,
aldosterone (dogs)
AMINO ACIDS, SERINE
SEE ALSO AMINO ACIDS. PHOSPHOSERINE
SEE ALSO PHOSPHOLIPIDS. PHOSPHOGLYCERIDES.
PHOSPHATIOYl SERINE
ROIHL 15958 06 X ray diffraction analysis ol thrombin
and neurotoxin
AMINO ACIDS, SERUM AMINO ACIDS
R01HL1632005 Vasoactive peptides which stimulate
smooth muscles (rats, human)
AMINO ACIDS, UREA CYCLE
SEE ALSO AMIDES, UREA
SEE ALSO DIAMINO ACIDS, ARGININE
ROlHL-20070-02 Alpha 1 antitrypsin deficiency (human,
hamsters)
AMINO ACIDS, VALINE
POlHL-15195-04 0001 Program proiect in biological
materials Design and synthesis
ROIHL 18819 07 Chemical studies on sickle cell
hemoglobin (human)
AMINO ACIDS METABOLISM (GENERAL)
SEE ALSO AMINO ACIDS TRANSPORT (GENERAL)
SEE ALSO METABOLIC DISORDERS INBORN,
AMINOACIDOPATHIES
SEE ALSO PROTEINS METABOLISM
ROIHL 09172-15 Protein and RNA synthesis in heart
muscle (rats)
POlHL-1 1310-12 0080 Mechanisms of cardiovascular
disease - Metabolism of the hypertrophied myocardium
(human)
ROIHL 12564-09 Control of respiration and blood gases
(human, dog)
** ROlHL-13193-09 Pathophysiology of post-traumatic and
shock states (rodents, dogs)
ROlHL-14706-07 Fetal hearts m organ culture (mice)
P50HL-1 7665-04 0029 Study of ischemic heart disease •
Myocardial protein synthesis and degradation in low oxygen
states (rabbit, dog)
ROlHL-18258-04 Regulation of protein degradation in
heart (rats)
POlHL-1857503 0005 Mechanisms of vascular changes
m hypertension Renin synthesis in normotensive and
hypertensive pigs (also rats, dogs)
POIHL 19242 02 0001 Study of vascular smooth muscle -
Energy metabolism and protein turnover in vascular smooth
muscle (rats)
ROlHL-20388-03 Regulation of protein turnover in diabetic
heart (rat)
POlHL-20552-02 0001 The development and regression of
cardiac hypertrophy - Biochemical events in cardiac
hypertrophy (rats)
** ROlHL-21381-02 Ammo acid metabolism in normal and
hypoxic myocardium (rabbits)
ROlHL-2210102 Hormone-substrate interaction in diabetic
myocyte (dogs, rats)
AMINO ACIDS SEQUENCE
SEE PROTEINS-PEPTIDES STRUCTURE, AMINO ACIDS
SEQUENCE
AMINO ACIDS TRANSPORT (GENERAL)
SEE ALSO AMINO ACYL TRNA
ROIHL 02835-21 Renal transport carrier for organic
compounds (dogs, rats)
ROlHL-04457-20 Cellular aspects of active transport (fish,
rabbits, anurans. turtles)
POIHL 06312-17 0034 Surgical cardiology ■ Metabolic
factors in cardiac function-Creatine phosphate depletion
(animals)
POlHL-06370-17 0004 Cardiopulmonary and renal
pathology research center - Lymphocytes in graft reiection
and immune surveillance (human)
ROlHL-09562-14 Cardiac protein synthesis, overload.
alcohol and anoxia (guinea pigs)
** ROlHL-13256-08 Ammo acid transport by red cell
membranes (pigeons)
P50HL-14212-07 0016 Correlated studies of pulmonary
fibrosis - Role of pulmonary alveolar macrophages in
fibrosis (human, rabbit)
ROlHL-16567-04 Differentiation of the heart-cell
membrane (mice, chick)
RClHL-19394-03 Biochemistry and regulation of taurine in
the heart (rats, guinea pigs, cats)
AMI
CtilulK in() inolKulii (tpcclt ol
Filly icid mtltboli'.m in type II
POIHI 19/3/0? 0001
ie-,pii4lury phy,iolaiy
alveolar crll% (ml-,)
'* ROIHI 2U:il>(iOI Piolein lurnovei and amino acid
llan^port by lung (rats)
ROIHI 21009 02 rilecli of air pollutanl-, on lung cillt in
culture (rats)
ROIHI 221/201 Hypotension, itnal ischemia and elltct ol
mannilol (dogs, rats)
•• ROIHL 22354 01 Alpha adrenergic ellecti on heart
metabolism (rats)
AMINOACIDURIA INBORN
Ml MIIAHOIII, DIMJUlJflC, INBORN, AMINOACIDOPATHIES
AMINOACRIDINES
S(f ACKIDINC, AMINOACRIDINES
AMINO ACYL TRNA
ROIHI 091/2 15 Protein and RNA synthesis in heart
muscle (rats)
ROIHL 20344 02 Regulation ol protein turnover in lung
tissue (rals)
AMINOACYLTRANSFERASES,
TRANSGLUTAMINASES
SFF ALSO BLOOD COAGULATION, FIBRIN STABILIZING FACTOR
ROIHL 16346 09 En^me assay lor blood clotting (human)
AMINO ALCOHOLS, ETHANOLAMINES
SEE ALSO CHOLINE
SEE ALSO PHOSPHOLIPIDS, PHOSPHOGIYCERIDES,
PHOSPHATIOYL ETHANOUMINE
SEE ALSO PHOSPHOLIPIDS, PHOSPHOGLYCERIDES.
PUSMALOGENS
ROIHL 22500 01 Conversion of choline to
phosphatidylcholine in lung (rabbits, pigs)
AMINO ALCOHOLS, PROPANOLS, ALPRENOLOL
POIHL 06308 18 0025 Mechanisms and therapy of
circulatory disease Subcellular calcium pools in the
genesis of arrhythmias (dogs)
ROIHL 19127 03 Synthesis of molecules for myocardial
imaging (rats)
ROIHL 20783 02 Airway reactivity B adrenoceptors and
prostaglandins (guinea pigs)
POlHL-20984 02 0005 Cellular mechanisms in cardiac
hypertrophy Neurohumoral receptors in cardiac grovrth
and compensatory hypertrophy (animals)
ROIHL 22415 01 Mechanisms responsible for disease
severity in asthma (human)
ROIHL 22522 01 Cardioseledivity of beta-ad renoceptor
antagonists
P-AMINOBENZOATE, PROCAINE
HYDROCHLORIDE
SEE ALSO PHENYLAMIDES, PROCAINE AMIDE
ROlHL-10503-13 Cardiac ion transport and ultrastructure
(rats, guinea pigs, rabbits)
R23HL-22895-01 Smoke inhalation- Biochemical and
cellular responses (rabbits, bacteria)
GAMMA-AMINOBUTYRIC ACID
SEE AMINO ACIDS. GAMMA-AMINOBUTYRIC ACID
AMINOFORMAMIDINE
SEE GUANIDINES
AMINOGLYCOLIPID (CERAMIDE TRIHEXISODE)
SEE GLYCOSPHINGOLIPIOS, CERAMIDE TRIHEXOSIOES
P-AMINOHIPPURATE
SEE AMINO ACIDS, HIPPURATES. P AMINOHIPPURATE
AMINOHYDROLASES
SEE ALSO OXIDOREDUCTASES, AMINO ACID OXIDASES
ROlHL-14456-07 Lung metabolism- Enzymes in the
pulmonary circulation (human, animals)
AMINOHYDROLASES, ADENOSINE DEAMINASE
ROIHL 1294409 Enzymatic and biochemical studies on
blood cells (human)
ROlHL-15125 07 Molecular pathology of genetic disorders
in man
AMINOHYDROLASES, ADENYLATE DEAMINASE
ROlHL-22538 01 Myosin as a multi-enzyme complex (dogs,
rabbits)
AMINOINDOLES
SEE BENZOPYRROLES, INDOLEAMINES (GENERAL)
ALPHA-AMINOISOBUTYRIC ACID
SEE AMINO ACIDS, ALPHA AMINOISOBUTYRIC ACID
ALPHA-AMINO,ALPHA-OXYACETIC ACID
SEE OXAMATES
AMINOPHYLLINE
SEE PURINES. XANTHINES, AMINOPHYLLINE
AMINOPOLYSACCHARIDES
SEE POLYSACCHARIDES, GLYCOSAMINOGLYCANS
BETA-AMINOPROPIONITRILE
SEE CYANIDES. AMINOALKYL NITRILES. BAPN
(contd)
•Excludes routine methodology OR covers only general proiects which preclude
**Oriented significantly to above subject
indexing at the specific level
M Grant has subproiects describing specific research aspects
See Appendix for investigators name and grant number.
P-A
AMINOPYRIDINES
SEE PYRIDINES, AMINOPYRIDINES
P-AMINOSAUCYLATES
SEE PHENYLCARBOXYLATES, SALICYUTES, PAMINO-
AMINO SUGARS
SEE CARBOHYDRATES, AMINO SUGARS
AMINO SULFIDES, CYSTAMINE
R01HL1363608 Effects of pharmacologic agents on heart
metabolism (human, rodents)
AMINOSULFONIC ACIDS
SEE ALSO SULFONAMIDES
R01HL18679-04 Synthetic protease inhibitors
AMINOSULFONIC ACIDS, TAURINE
ROlHL-09234-13 Amino acids of contractile proteins of
falling hearts (dogs, hamsters)
ROIHL 13636-08 Effects of pharmacologic agents on heart
metabolism (human, rodents)
ROlHL-18554-03 Taurine metabolism in mammalian heart
(rodents, cattle, swine)
ROlHL-19394-03 Biochemistry and regulation of taurine in
the heart (rats, guinea pigs, cats)
R01HL-202U-02 Role of taurine in the heart (dogs, rats
mice)
POlHL-20592-02 0003 Cell biology of cardiac and
skeletal muscle Cellular magnesium and anion activities
in ion-specific raicroelectrodes (frogs)
AMINOTHIOLS, CYSTEAMINE
POlHL-06370-17 0015 Cardiopulmonarv and renal
pathology research center ■ Pathogenesis of chemically
induced tissue injury (rats)
ROIHL 1363608 Effects of pharmacologic agents on heart
metabolism (human, rodents)
AMINOTRANSFERASES, ALANINE
TRANSAMINASE
P01HL-06312-17 0053 Surgical cardiology - Enzyme
pattern following cardiac surgery (human)
ROlHL-22838-01 Post-transfusion hepatitis in newborn
children
AMINOTRANSFERASES, ASPARTATE
TRANSAMINASE
P01HL06312 17 0053 Surgical cardiology ■ Enzyme
pattern following cardiac surgery (human)
" ROlHL-1303508 Heart mitochondrial malate
dehydrogenase regulation
ROlHL-2226502 Isozymes of heart glutamate aspartate
transaminase (swine, ducks)
AMITRIPTYLINE
SEE CYCLOHEPTANES. AMITRIPTYLINE
AAUMONIA
ROlHL-00759-29 Regulation of electrolyte and acid base
equilibrium (dogs)
R01HL12564-09 Control of respiration and blood gases
(human, dog)
R01HL-2138I02 Amino acid metabolism in normal and
hypoxic myocardium (rabbits)
AMMONIA-LYASES, ASPARTASE
R01HL18288-04 Intraoperative protection of the
myocardium (dogs, rats)
AMMONIUM
R01HL19746-03 Proliferation ?nd differentiation of
alveolar macrophages (mice, hamsters)
AMMONIUM QUATERNARY
SEE ALSO CHOLINE
SEE ALSO PHENYLALKYLAMINES, BENZYLAMINES, BRETYLIUM
TOSYLATE
SEE ALSO PHENYLAMINES, NEOSTIGMINE
ROlHL-02835-21 Renal transport carrier for organic
compounds (dogs, rats)
RO1HL-I9782-02 Pharmacologic studies on the ischemic
heart (dogs)
ROlHL-20622-02 Pulmonary uptake and accumulation of
drugs (rabbits, rats)
AMMONIUM QUATERNARY, BETAINE
COMPOUNDS, CARNITINE
P01HL0630818 0040 Mechanisms and therapy of
circulatory disease - Metabolism and fatty acid utilization-
Heart electrical stability (rats, dogs)
ROIHL 13028-09 Regulation of myocardial fatty acid
metabolism (rats)
R01HL13302-09 Uptake and metabolism of lipids by the
liver (rats)
R01HL1363608 Effects of pharmacologic agents on heart
metabolism (human, rodents)
ROIHL 14730-07 Fatty acid beta-oxidation in normal and
ischemic hearts (rabbits)
R01HL-1568I06 Coronary flow studies of partially
obstructed vessels (dogs)
ROIHL 17736-04 Metabolic change during cardiac
ischemia (rats, dogs)
ROlHL-20308-02 Regulation of myocardial acylcarnitine
transport (rats)
14
ROIHL 2120902 Alterations of metabolism in ischemic
myocardium (swine)
ROlHL-228 13-01 Palmitylcarnitine inhibition of ion pumps
in ischemia (dogs)
*• ROlHL-2316101 0002 Biology of myocardial ischemia -
Palmitylcarnitine inhibition of ion pumps in myocardial
ischemia (dog, sheep)
AiMMONIUM QUATERNARY, CHOLESTYRAMINE
P01HL06835-17 0064 Cardiovascular disease ■ Studies
in atherosclerosis (human, animals)
ROlHL-08634-15 Enzymic cholesterol synthesis (human.
rats, protozoa, yeast)
R01HL1208510 Lipoprotein-carbohydrate metabolism
(human, rats)
P50HL 14230-07 0093 A/S SCOR-lipids, atherosclerosis
and thrombosis ■ Clinical studies involving cellular lipid
content (human)
P50HL 14236-05 0009 Prevention of premature
arteriosclerosis - Clinical studies on cholesterol metabolism
(human)
P50HL1506207 0018 Study of lipoproteins, artery wall.
and atherosclerosis - Reversal of atherosclerosis in
monkeys
R01HL16364-04 Regulation of lipid biosynthesis and
transport (rats, swine. Xenopus)
ROlHL-16587-04 Cholesterol binding saponins and
atherosclerosis (monkeys)
R01HL17818-05 Metabolism of cholesterol and cholesterol
in man (also rats, monkeys)
R01HL18454-03 Maximal exercise testing in
hypertipidemic children
ROlHL-22567-01 Validation of a cholesterol absorption
method in man
NOlHV-22913-09 Lipid research clinic
AMMONIUM QUATERNARY,
TETRAETHYLAAAMONIUM COMPOUNDS
R01HL1409207 Homeostatic regulation of plasma choline
(rats, dogs, chickens)
ROlHL-21371-02 Energy loss microanalysis of myocardial
cations
ROlHL-22426-01 Initiation of the heartbeat-A voltage-
clamp study (bullfrogs, rabbits)
ROlHL-22562-02 Mechanism of cardiac action potential
propagation (tunicates)
AMNIOCENTESIS
SEE PREGNANCY, AMNIOCENTESIS
AMP
SEE ARTHRITIS AND METABOLIC DISEASES PROGRAM
PROJECT COMMIHEE
SEE PURINE NUCLEOTIDES. ADENINE NUCLEOTIDES, AMP
AMP CYCLIC
SEE PURINE NUCLEOTIDES. ADENINE NUCLEOTIDES AMP
CYCLIC
AMPHETAMINE
SEE PHENYULKYLAMINES. AMPHETAMINE
D-AMPHETAMINE
SEE PHENYULKYUMINES, DAMPHHAMINE
AMPHIBIANS, ANURANS*
R01HL04457-20 Cellular aspects of active transport (fish,
rabbits, anurans. turtles)
R01HL13929-06 Single nephron response to chronic
obstruction (frogs, rats)
ROlHL-14523-07 Generation and regulation of force in
smooth muscle (animals)
AMPHOTERICIN-B
SEE ANTIBIOTICS. AMPHOTERICINB
AMPUTATION
SEE SKELETAL SYSTEM, LIMB, AMPUTATION
ALPHA-AM YLASE
SEE CARBOHYDRASES, ALPHA-AMYLASE
AMYL NITRITE
SEE NITRITES, AMYL NITRITE
AMYLOID SUBSTANCE
SEE GLOBULINS, AMYLOID SUBSTANCE
AMYLOIDOSIS (INCLUDING NON-INBORN
CASES)
SEE METABOLIC DISORDERS (INBORN). AMYLOIDOSIS
ANABOLIC FACTORS
SEE GROWTH FACTORS (INCL. ANABOLICS)
ANAEROBES, BACTERIAL
SEE MICROORGANISMS. ANAEROBES
ANAEROBIC MICROORGANISMS
SEE MICROORGANISMS. ANAEROBES
ANAEROBIOSIS
SEE RESPIRATION INTERNAL, ANAEROBIOSIS
ANALGESICS
SEE NEUROPHARMACOLOGICAL AGENTS, ANALGESICS
•Excludes routine methodology OR covers only general projects which preclude indexing
Onented significantly to above subject.
AND
ANALOGS OF HALOGENATED BIPHENYLS AND
TRIPHENYLS
SEE HALOBENZENES. HALOGENATED BIPHENYLSTRIPHENYLS
AND ANALOGS
ANALYSIS AND EVALUATION OF SYSTEMS
(GENERAL)
SEE INFORMATION AND COMMUNICATION, SYSTEMS ANALYSIS
ANALYSIS OF BIOMEDICAL RESEARCH
PROGRAMS
SEE HEALTH SCIENCES RESEARCH ANALYSIS-EVALUATION-
PLANNING
ANALYSIS OF HEALTH CARE SERVICES AND
RESOURCES
SEE HEALTH CARE (SERVICES)(RESOURCES) ANALYSIS AND
EVALUATION
ANALYTICAL CHEMISTRY
SEE CHEMISTRY. ANALYTICAL
ANALYTICAL ELECTRON MICROSCOPY
SEE CHEMISTRY. ANALYTICAL METHODS. SPECTROMETRY
ELECTRON PROBE*
ANALYTICAL METHODS
SEE CHEMISTRY. ANALYTICAL METHODS*
ANALYTICAL ULTRACENTRIFUGATION
SEE PHYSICAL SEPARATION, ULTRACENTRIFUGATION
ANALYTICAL*
ANAPHYLAXIS
SEE HYPERSENSITIVITY, ANAPHYLAXIS
ANATOMY (GENERAL)*
SEE ALSO BODY PHYSICAL CHARACTERISTICS (GENERAL)
SEE ALSO NEUROANATOMY
P01HL03 174-23 0007 Mechanisms of acute vascular
reaction to injury ■ Healing of injured myocardium-Basal
lamina scaffold (human, rats, dogs)
POlHL-06312-17 0052 Surgical cardiology ■ Assay of
metabolic variables of rat heart
ROlHL-08359-14 Morphopharmacology of vascular
adrenergic transmission (rabbits, rats)
ROlHL-12486-10 Structure-function correlation in the
atrium (rabbits)
R01HL17969-04 Function and structure of semilunar
valves (dogs)
** POlHL-18575-03 0012 Mechanisms of vascular changes
in hypertension ■ Anatomy core facility
ROlHL-18639-03 Human anatomy for cardiac prostheses
(human)
R23HL-21253-01 Anatomical models in computer-aided
image analysis
ROlHL-22963-01 Symbolic logic analysis of congenital
heart disease (human)
ANATOMY MICROSCOPIC (HISTOLOGY)
SEE HISTOLOGY (GENERAL)*
ANDROGENS
SEE ANDROSTANE SERIES. ANDROGENS
ANDROMEDOTOXINS
SEE TOXICOLOGY, PUNT POISONS, GRAYANOTOXINS
ANDROSTANE SERIES, ANDROGENS
ROlHL-03357-21 Humoral control of blood cell formation
and release (rats, mice)
ROlHL-0697518 Pathogenesis and prevention of
hypertension (rats)
ROlHL-17516-04 Role of androgen as a risk factor in
atherogenesis (human, animals)
ROlHL-17865-04 Studies on aging-Effects of sex
hormones (rats, dogs)
ROIHL- 17909-04 Drug treatment of vascular scleroprotein
defects (human, turkeys)
ROlHL-18012-04 Cellular defects in nocturnal
hemoglobinuria (human)
POlHL-18645-03 0007 Biology of the artery wall and
atherosclerosis - Lipoprotein metabolism in subhuman
primates
ROlHL-21418-02 Experimental myocardial infarction (rats)
ROlHL-22812-01 Regulation of hepatic production of HDL
(rats)
ANDROSTANE SERIES, ANDROSTANOLONE
ROlHL-22040-01 Regulation of lysyl-cross-linking in
vascular tissue (rats, turkeys)
ANDROSTANE SERIES, ANDROSTENEDIOL
P50HL-18318-03 0009 Pathogenesis and complications of
hypertension - The mineralocorticoid-hypertensive syndrome
in man
ROlHL-18730-03 Role of mineralocorticoids in low renin
hypertension (human, rats)
ANDROSTANE SERIES, ANDROSTERONE
P50HL-18323-04 0038 SCOR hypertension center -
Unknown adrenocortical mechanisms in hypertension
(human)
at the specific level.
M Grant has subprojecis describing specific research aspects.
See Appendix for investigator's name and grant number
(contd)
.-Sff^jtt v4-jt^Atfb» A!ir>
AND
ANDROSTANE SERIES,
OEHYOROEPIANDROSTERONE
ROIHI 1810.' 11.' Kole ol Ihf .iilifnal corln in human
hyp«r1ension
PSOHl 18318 03 0004 Palhojenesis and complic«t(ons ot
hypertension Sttcoid and lenin pcoliles in hypertension
(Ills, human)
PSOHL 18318 03 0009 Pathogenesis and complications ot
hypertension The mineialocorticoid hypertensive syndrome
in man
ROIHI 18730 03 Role ol mineialocorticoids in low renin
hypertension (hiinuin i.ils)
ANDROSTANE SERIES, OXANDROLONE
POIHI 185/4 03 0006 lipoprotein methodology and
biomedical applications Lipoprotein transformation,
lipolytic enzymes, diet and lipid lowering agents
ROIHL 22607 01 Role ol apolipoprotem F in lipoprotein
metabolism (human)
ANDROSTANE SERIES, PANCURONIUM
R?3HL 22309 01 Cardiovascular pharmacodynamics in
immature dogs
ANDROSTANE SERIES, TESTOSTERONE
POIHI 16387 04 0002 The blood vessel and
thrombogenesis Hormonal effects on thrombogenesis
(rats, rabbits)
ROIHL 1772104 Effect ol sex hormones on vascular
connective tissue (rats)
ROIHL 2036401 Episodic hypertension associated with
human behavior (air traffic controllers)
ANDRcSTANE SERIES 5 BETA,
ETIOCHOLANOLONE
P60HL15170 05 0017 Support for center for sickle cell
anemia - Control of hemoglobulin synthesis (human)
ANDROSTANOLONE
SEE ANDROSTANE SERIES. ANDROSTANOLONE
ANDROSTENEDIOL
SEE ANDROSTANE SERIES. ANDROSTENEDIOL
ANDROSTENOLONE
SEE ANDROSTANE SERIES. OEHYOROEPIANDROSTERONE
ANDROSTERONE
SEE ANDROSTANE SERIES, ANDROSTERONE
ANEMIA
SEE BLOOD AND RE DISORDERS. ANEMIA
ANEMIA APLASTIC
SEE BLOOD AND RE DISORDERS. ANEMIA APUSTIC
ANEMIA APLASTIC CONGENITAL
SEE BLOOD AND RE DISORDERS. ANEMIA APUSTIC
CONGENITAL
ANEMIA HEMOLYTIC
SEE BLOOD AND RE DISORDERS. ANEMIA HEMOLYTIC
ANEMIA HEMOLYTIC AUTOIMMUNE
SEE BLOOD AND RE DISORDERS, ANEMIA HEMOLYTIC
AUTOIMMUNE
ANEMIA HEMOLYTIC CONGENITAL (FAMILIAL)
SEE BLOOD AND RE DISORDERS, ANEMIA HEMOLYTIC
CONGENITAL (GENERAL)
ANEMIA HEMOLYTIC IDIOPATHIC
SEE BLOOD AND RE DISORDERS. ANEMIA HEMOLYTIC
AUTOIMMUNE
ANEMIA MEGALOBLASTIC
SEE BLOOD AND RE DISORDERS. ANEMIA MEGALOBLASTIC
ANEMIA SIDEROBLASTIC
SEE BLOOD AND RE DISORDERS, ANEMIA SIDEROBUSTIC
ANESTHESIA
SEE SENSORY DEPRESSION, ANESTHESIA (GENERAL)
ANESTHESIA, BLOCK
SEE SENSORY DEPRESSION. ANESTHESIA CONDUCTION
ANESTHESIA, CONDUCTION
SEE SENSORY DEPRESSION, ANESTHESIA CONDUCTION
ANESTHESIA, INHALATION
SEE SENSORY DEPRESSION. ANESTHESIA (GENERAL).
INHALATION
ANESTHESIA, LOCAL
SEE SENSORY DEPRESSION. ANESTHESIA CONDUCTION.
LOCAL
ANESTHESIA, REGIONAL
SEE SENSORY DEPRESSION. ANESTHESIA CONDUCTION
ANESTHESIA COMPLICATIONS
SEE DISEASES, COMPLICATIONS. ANESTHESIA RELATED
ANESTHETICS
SEE NEUROPHARMACOLOGICAL AGENTS. ANESTHETICS
M
ANESTHETICS. LOCAL
S(( NfUROPHARMACOIOGICAl AGENTS. ANESTHETICS.
lOCAt
ANEURYSM
SI I (AHDIOVASCUIAR DISORDERS. ANEURYSM
ANEURYSMS, CARDIAC
SEE HEART DISORDfRS ANEURYSMS
ANGER
SEE PSYCHOLOGY, EMOTIONS. ANGER
ANGER CAMERA SCANNING
SEE RADIOAUTOGRAPHY RADIONUCLIDE SCANNING'
ANGIITIS
SEE CARDIOVASCUUR DISORDERS. ARTERITIS
SEE CARDIOVASCULAR DISORDERS. THROMBOPHLEBITIS
ANGINA, INTESTINAL
SEE GASTROINTESTINAL CIRCULATORY DISORDERS.
CIRCULATORY INSUFFICIENCY
ANGINA PECTORIS
SEE HEART DISORDERS. CORONARY. ANGINA PECTORIS
ANGIOCARDIOGRAPHY
SEE HEART VISUALIZATION, ANGIOCARDIOGRAPHY*
ANGIOCARDIOULTRASONOGRAPHY
SEE HEART VISUALIZATION.
ANGIOCARDIOULTRASONOGRAPHY*
ANGIOEDEMA HEREDITARY
SEE METABOLIC DISORDERS INBORN. ANGIONEUROTIC
EDEMA (HEREDITARY)
ANGIOGENESIS
SEE CARDIOVASCUUR SYSTEM. ANGIOGENESIS
ANGIOGENESIS FACTOR, TUMOR
SEE NEOPUSMS VASCUUR SUPPLY, TUMOR ANGIOGENESIS
FACTOR
ANGIOGRAPHY
SEE CARDIOVASCUUR VISUALIZATION. ANGIOGRAPHY*
ANGIOHEMOPHILIA
SEE BLOOD COAGUUTION DISORDERS, VON VKILLEBRAND'S
DISEASE
ANGIOMA
SEE NEOPUSMS OF CARDIOVASCUUR SYSTEM
ANGIONEUROTIC EDEMA (HEREDITARY)
SEE METABOLIC DISORDERS INBORN. ANGIONEUROTIC
EDEMA (HEREDFTARY)
ANGIOSPERMS (GENERAL)
SEE PUNTS, ANGIOSPERMS (GENERAL)*
ANGIOTENSIN
SEE PEPTIDES, VASOACTIVE PEPTIDES. ANGIOTENSIN
ANGIOTENSIN II
SEE PEPTIDES. VASOACTIVE PEPTIDES, ANGIOTENSIN II
ANGIOTENSINASE
SEE PROTEASES AND PEPTIDASES, ANGIOTENSINASE
ANGIOTENSINASE C
SEE PROTEASES AND PEPTIDASES,
PROLYLCARBOXYPEPTIDASE
ANGIOTENSINOGEN
SEE PEPTIDES, VASOACTIVE PEPTIDES. ANGIOTENSINOGEN
ANGIOTENSINRENIN-ALDOSTERONE-
ASSOCIATED HYPERTENSION
SEE CARDIOVASCUUR DISORDERS. HYPERTENSION
(SYSTEMIC), ANGIOTENSIN-RENIN-ALDOSTERONE-
ASSOCIATED
ANGIOTOMOGRAPHY
SEE CARDIOVASCUUR VISUALIZATION. ANGIOTOMOGRAPHY*
ANHYDRIDES
SEE ETHERS
SEE OXIDES (SEE ALSO SPECIFICS)
ANIMAL AGE AND LIFE STAGES
SEE AGE (ANIMAL)
ANIMAL BEHAVIOR
SEE PSYCHOLOGY. BEHAVIOR ANIMAL
ANIMAL CARE
SEE ANIMALS. VETERINARY SCIENCE. ANIMAL CARE
ANIMAL FACILITIES, RESOURCES
SEE ALSO ANIMALS. VETERINARY SCIENCE
SEE ALSO MAMMALS. PRIMATE COLONIES
** N01HB-42971-I2 Chimpanzees for hepatitis research
** POIHL-12373 10 0019 Cardiopulmonary physiology and
pathophysiology - Free ranging animal facility
** P50HL-14164-07 0025 A/S SCOR -Comparative and
experimental atherosclerosis - Animal care resource and
laboratory animal medicine unit (monkeys, pigeons)
•Excludes routine methodology OR covers only general projects which prccludi
**Orlenled significantly to above subject,
ie indexing at the specific level
M Grant has subprojects describing specific
See Appendix for investigator's name and grant number
ANO
P'jOHI 14164 0/ n0?8 A/S SCOR Comparative and
eiperimenlal atheroscliiosis Hyper and
hyporisponsiveniit to ditliry choleilirol (Alitcan grMn
monkey)
P50HI 14164 0/ 0029 A/S SCOR Comparalive and
experimental atheroulerotit DtvelopmenI of pigeon
substrains
•• P'jOHl 14214 0/ 00)5 Newborn lung center lor hyaline
membrane disease Coir Animal care lacilily
*" POIHI 149850/001/ Adaptation to hypoxia Core
laboratories
P50HI 1506? 0/ 0021 Study of lipoproteins, artery wall.
and alhrioscleiosi'. Core laboratcjries
•• POIHI 15194 0/ 9000 Psihophy.iology ol
caidiopulmonary dysfunction Animal laboratory core
•• ROIHL 1564/06 Hematopoietic studies ol cyclic
hemalopoiesis (dogs)
•* P60HI 1/269 04 0024 National heart and blood vessel
rpse^iich and -r - ' ■'•■- ■ ' '' ""eclion ol
experimenlaUo , ,.eiy Core facility
*• P50HL 1/646 04 0004 Study of ischemic heart disease
Core experimental animal laboratories
** P50HL 18318 03 0002 Pathogenesis and complications ol
hypertension Core experimental animal facility (rats,
rabbits)
•* POIHL 18575 03 0010 Mechanisms of vascular changes
in hypertension Hypertensive pig Core
•* POIHL 20993 02 0010 Population dynamics of arterial
cells in atherogenesis Animal care and development and
standardization ol animal models Core
** ROIHL 22227 01 A new '.ource of hyaluronidase and
anticoagulants (leeches)
** NOIHV 72978 02 Development of models of hypertension
** NOIHV 7298002 Development of models of hypertension
ANIMAL HUSBANDRY
SEE ANIMALS. VETERINARY SCIENCE
ANIMAL POISONS
SEE TOXICOLOGY, ANIMAL POISONS
ANIMALS (SEE SPECIFIC ANIMALS)
SEE AGE (ANIMAL)
SEE AGE (ANIMAL), INFANTS MORTALITY
SEE ENVIRONMENT, ECOLOGY ANIMAL
SEE GENETICS. POPUUTION GENETICS ANIMAL
SEE PSYCHOLOGY, BEHAVIOR ANIMAL
ANIMALS, CHORDATES, VERTEBRATES*
SEE ALSO BIROS*
SEE ALSO FISH*
SEE ALSO MAMMALS*
SEE ALSO REPTILES*
ROIHL 1999502 Sensory transduction m cardiac
mcchanoreceptors (cats, frogs, rats)
ROlHL-22562-02 Mechanism of cardiac action potential
propagation (tunicates)
ANIMALS, VETERINARY MEDICINE
SEE ALSO POPUUTION STUDIES ANIMAL. EPIZOOTIOLOGY
P50HL14164-07 0025 A/S SCOR- Comparative and
experimental atherosclerosis Animal care resource and
laboratory animal medicine unit (monkeys, pigeons)
** ROlHL-18947-02 Indirect mean arterial pressure
(mammals)
P50HL-19187-02 0013 Pediatric pulmonary SCOR Hyaline
membrane disease - Research resources core
P50HL-19362-02 0004 A/S SCOR -Atherosclerosis in
nonhuman primates - Selective breeding for characters
related to atherosclerosis (baboons)
** P50HL-19362-02 0016 A/S SCOR- Atherosclerosis in
nonhuman primates - Core laboratory -Animal services
(baboon)
ANIMALS, VETERINARY SCIENCE
SEE ALSO ANIMAL FACILITIES. RESOURCES
ROlHL-13645 U Tryptophan-induced pulmonary
emphysema (cattle, goats, rabbits)
** POlHL-14388-07 9001 Regulation of the circulation in
pathological states - Core facility for hypertensive animal
colony (rats)
NOlHV-62905-02 Non-human primate models of
arteriosclerosis
ANIMALS, VETERINARY SCIENCE, ANIMAL CARE
** NOlHI-72900-01 Maintenance of the NHLBI sheep colony
P50HL-14164-07 0025 A/S SCOR -Comparative and
experimental atherosclerosis - Animal care resource and
laboratory animal medicine unit (monkeys, pigeons)
P50HL-1421407 0035 Newborn lung center for hyaline
membrane disease - Core-Animal care facility
POlHL-14388-07 9001 Regulation of the circulation in
pathological states - Core facility for hypertensive animal
colony (rats)
" P50HL-19362-02 0016 A/S SCOR -Atherosclerosis in
nonhuman primates ■ Core laboratory -Animal services
(baboon)
ANION
SEE IONS. ANION
ANOREXIA
SEE NUTRIENT INTAKE DISORDERS, APPETITE DISORDERS,
ANOREXIA
(contd)
research aspects
ANO
ANOREXIGENIC DRUGS
SEE NUTRIENT INTAKE ACTIVITY. APPETITE DEPRESSANTS
ANOXIA
SEE RESPIRATORY GAS LEVELS, HYPOXIA
ANOXIA NEONATORUM
SEE RESPIRATORY GAS LEVELS. HYPOXIA NEONATORUM
ANOXIA RESPIRATORY
SEE RESPIRATORY GAS LEVELS. HYPOXIA. RESPIRATORY
ANTAGONISM
SEE DRUGS AND PHYSICAL AND/OR CHEMICAL AGENTS
INTERACTION
SEE DRUGS INTERACTION
SEE PHYSICAL AND/OR CHEMICAL AGENTS INTERACTION
(BIOLOGICAL AND ECOLOGICAL)
ANTEPARTUM DIAGNOSIS
SEE PREGNANCY. ANTEPARTUM DIAGNOSIS
ANTHOZOA
SEE COELENTERATES. ANTH020A*
ANTHROPOLOGY, PHYSICAL
SEE BODY PHYSICAL CHARACTERISTICS (GENERAL)
ANTHROPOMETRY
SEE BODY PHYSICAL CHARACTERISTICS (GENERAL)
ANTIACIDOSIS DRUGS
SEE BODY FLUID BAUNCE. ACID-BASE. ANTIACIDOSIS DRUGS
ANTIADRENERGICS
SEE NEUROPHARMACOLOGICAL AGENTS. SYMPATHOLYTIC
ANTIALIERGY DRUGS
SEE HYPERSENSITIVITY. ANTIALLERGY DRUGS
ANTI-ANTIBODIES
SEE IMMUNOLOGY, ANTIBODIES. ANTI-ANTIBODIES
ANTIARRHYTHMIC AGENTS
SEE CARDIOVASCULAR AGENTS. ANTIARRHYTHMIC AGENTS
ANTIATHEROGENIC AGENTS
SEE CARDIOVASCUUR AGENTS. ANTIATHEROGENIC AGENTS
ANTIBACTERIAL AGENTS
SEE COMMUNICABLE DISEASE CONTROL AGENTS
ANTIBACTERIAL
ANTIBIOTICS
SEE ALSO COMMUNICABLE DISEASE CONTROL AGENTS
ROlHL-12528-10 NMR relaxation of liquid ciystal systems
ROlHL-14775-08 Mechanisms of drug action in vascular
smooth muscle (dog. rabbits)
R01HL-I5619-05 Regulation of prothrombin synthesis In
cultured cells (rats)
ROlHL-16474-05 Antibiotic-ion interactions (model
membranes)
ROlHL-17751-03
ROlHL-18002-03
function (rats)
ROlHL-19722-03
(models)
ROlHL-19818-02
(rabbits, human)
ROlHL-20963-01
ROlHL-22888-01
Experimental endocarditis (rabbits)
Circulatory shock, trauma and RE-system
Aerosol growth in the respiratory system
Endocarditis on prosthetic heart valves
Experimental lung abscess (rabbits)
Prosthetic valve endocarditis -Etiology
and therapy (dogs)
ANTIBIOTICS, ACTINOMYCIN
POlHL-06314-17 0064 Immunologic mechanisms in
cardiovascular disease - Diabetic vascular disease (human,
rats, mice)
ANTIBIOTICS, ACTINOMYCIN D
POlHL-06370-17 0004 Cardiopulmonary and renal
pathology research center - Lymphocytes in graft rejection
and immune surveillance (human)
POIHL-14388-07 0190 Regulation of the circulation in
pathological states • Mechanisms of the renal actions of
aldosterone (rats)
ANTIBIOTICS, AORIAMYCIN
POlHL-06370-17 0014 Cardiopulmonary and renal
pathology research center - Quantitative morphology in
cardiac disease (human, rats, dogs)
ROlHL-13636-08 Effects of pharmacologic agents on heart
metabolism (human, rodents)
ANTIBIOTICS, AMPHOTERICIN-B
R01HL-16660-06 Phospholipid-cholesterol and
phospholipidprotein interactions
ANTIBIOTICS, ANTINEOPLASTIC ANTIBIOTICS
(GENERAL)
SEE ALSO ANTIBIOTICS. ACTINOMYCIN
SEE ALSO ANTIBIOTICS. ACTINOMYCIN D
SEE ALSO ANTIBIOTICS, ADRIAMYCIN
SEE ALSO ANTIBIOTICS, BLEOMYCIN
SEE ALSO ANTIBIOTICS, DAUNOMYCIN
SEE ALSO ANTIBIOTICS, KANAMYCIN
SEE ALSO ANTIBIOTICS, MITOMYCIN C
ROlHL-18606-04 Pathogenesis and measurement of
pulmonary edema (human, rabbits, dogs)
16
ANTIBIOTICS, BACITRACIN
RC1HL-16101-05 Protein-lipid interaction (bacteria,
models)
ANTIBIOTICS, BLEOMYCIN
POIHL 161 18 06 0003 Study of emphysema - Degradation
of collagen and elastin (human, hamsters, mice)
R01HL18606 04 Pathogenesis and measurement of
pulmonary edema (human, rabbits, dogs)
POlHL-19717-02 0008 Response of the lung to injury -
Experimental models of lung disease
R01HL19720-03 Evaluation of antifibrotic agents in
pulmonary fibrosis (rats)
ANTIBIOTICS, DAUNOMYCIN
ROlHL-20856-02 Platelet transfusions-Usage and
complications (human)
ANTIBIOTICS, FILIPIN
ROlHL-16660-06 Phospholipid-cholesterol and
phospholipidprotein interactions
ROlHL-2205201 Organization of free cholesterol in serum
lipoproteins (human, dogs)
ANTIBIOTICS, GENTAMICIN
ROIHL 14775-08 Mechanisms of drug action in vascular
smooth muscle (dog. rabbits)
ANTIBIOTICS, GRAMICIDIN (UNSPECIFIED)
ROlHL-12528-10 NMR relaxation of liquid crystal systems
R01HL13256-08 Amino acid transport by red cell
membranes (pigeons)
ANTIBIOTICS, KANAMYCIN
ROlHL-2257301 Treatment of post surgical
vasoconstriction (dogs, monkeys, human, rats)
ANTIBIOTICS, MITOMYCIN C
ROlHL-08696-15 0013 Orthotopic heart transplantation -
Transplantation immunology-Cardiac heterotransplantation
(rabbits, dogs)
ANTIBIOTICS, NEOMYCIN
P50HL14236-05 0009 Prevention of premature
arteriosclerosis - Clinical studies on cholesterol metabolism
(human)
ROlHL-22567-01 Validation of a cholesterol absorption
method in man
ANTIBIOTICS, NOVOBIOCIN
ROlHL-1569812 Factors affecting the action of
anticoagulants (rats, human)
ANTIBIOTICS, NYSTATIN
ROlHL-16660-06 Phospholipid-cholesterol and
phospholipidprotein interactions
ANTIBIOTICS, OLIGOMYCIN
R01HL19378-03 Relation of mitochondrial changes to
cardiac failure (dogs, rats)
ANTIBIOTICS, PENICILLIN
P60HL15996-06 0003 Cincinnati comprehensive sickle
cell center - Prophylactic penicillin in treatment of sickle
cell anemia (human)
ROlHL-201 70-02 Pulmonary infection in splenectom ized
animals (mice)
ANTIBIOTICS, PENICILLIN G
R23HL-2289501 Smoke inhalation -Biochemical and
cellular responses (rabbits, bacteria)
ANTIBIOTICS, RISTOCETIN A
P50HL142 17-08 0058 Specialized center of research in
thrombosis ■ Mechanisms of induction and inhibition of
platelet reaction (human, pig)
P50HL14217-08 0062 Specialized center of research in
thrombosis - Coagulation section -Factor VIII and Factor XII
(human, cattle)
ROlHL-15230-05 Molecular basis of V Willebrand's disease
and hemophilia (human, cattle)
POlHL-15596-05 0014 Coagulation, fibrinolysis.
hemostasis and hepatitis • Von Willebrand factor and
platelet retention in glass bead columns (swine)
POlHL-17430-05 0001 Control of coagulation ■ Porcine
von Willebrand's disease
** P01HL17430-05 0002 Control of coagulation ■ Isolation
of ristocetin-von Willebrand factor (swine)
P50HL-18828-03 0001 Specialized center of research in
thrombosis - Membrane biology and hemostasis (human)
ROlHL-19278-03 Ristocetin induced platelet aggregation
(human)
ROlHL-20517-03 Diabetes, somatotropin, factor VIII and
atherosclerosis (human, animal)
ANTIBIOTICS, VALINOMYCIN
R01HL12528-10 NMR relaxation of liquid crystal systems
ROlHL-23392-01 Membrane binding and transport of
calcium and potassium ionophores
ANTIBIOTICS, VANCOMYCIN
R01HL19278-03 Ristocetin induced platelet aggregation
(human)
ANTIBODIES
SEE IMMUNOLOGY, ANTIBODIES
ANT
ANTIBODIES, BACTERIAL
SEE IMMUNOLOGY, ANTIBODIES BACTERIAL
ANTIBODIES, FUNGAL
SEE IMMUNOLOGY, ANTIBODIES FUNGAL
ANTIBODIES, VIRAL
SEE IMMUNOLOGY, ANTIBODIES VIRAL
ANTIBODIES NEOPLASTIC
SEE NEOPWSMS IMMUNOLOGY, TUMOR ANTIBODIES
ANTIBODIES SENSITIZING HUMORAL
(CIRCULATING) (SERUM)
SEE HYPERSENSITIVITY. SENSITIZING ANTIBODIES HUMORAL
ANTIBODIES TO MICROBIAL TOXINS
SEE IMMUNOLOGY. ANTITOXINS
ANTIBODY-ANTIGEN REACTIONS
SEE IMMUNOLOGY. ANTIGEN-ANTIBODY REACTIONS
ANTIBODY-ANTIGEN REACTIONS IN VITRO
SEE IMMUNOLOGY. SEROLOGY*
ANTIBODY BIOSYNTHESIS
SEE IMMUNOLOGY. ANTIBODY FORMATION
ANTIBODY FORMATION
SEE IMMUNOLOGY. ANTIBODY FORMATION
ANTIBODY SPECIFICITY
SEE IMMUNOLOGY. ANTIBODY SPECIFICITY
ANTIBODY STRUCTURE
SEE GLOBULINS. GAMMA GLOBULINS. IMMUNOGLOBULIN
STRUCTURE
ANTICHOLINERGIC AGENTS
SEE NEUROPHARMACOLOGICAL AGENTS,
PARASYMPATHOLYTIC
ANTICOAGULANTS
SEE BLOOD COAGULATION. ANTICOAGULANTS
ANTICONVULSANTS
SEE NEUROPHARMACOLOGICAL AGENTS. ANTICONVULSANTS
ANTIDEPRESSANTS
SEE PSYCHOPHARMACOLOGICAL AGENTS, ANTIDEPRESSANTS
ANTIDIURESIS
SEE KIDNEY FUNCTION, ANTIDIURESIS
ANTIDIURETIC HORMONE
SEE PITUITARYDIENCEPHALON HORMONES. VASOPRESSIN
ANTIDIURETICS
SEE KIDNEY FUNCTION, ANTIDIURETICS
ANTIDROMIC IMPULSES
SEE NEUROPHYSIOLOGY, NEURAL TRANSMISSION
ANTIDROMIC IMPULSES
ANTIESTERASES
SEE ENZYME INHIBITORS, ANTIESTERASES
ANTIFERTILITY DRUGS
SEE FERTILITY, ANTIFERTILITY DRUGS
ANTIFIBRINOLYTIC AGENTS
SEE BLOOD COAGUUTION, ANTIFIBRINOLYTIC AGENTS
ANTIFUNGAL AGENTS
SEE COMMUNICABLE DISEASE CONTROL AGENTS
ANTIFUNGAL
ANTIFUNGAL ANTIBODIES
SEE IMMUNOLOGY, ANTIBODIES FUNGAL
ANTIGEN-ANTIBODY REACTIONS
SEE IMMUNOLOGY, ANTIGEN-ANTIBODY REACTIONS
ANTIGEN-ANTIBODY REACTIONS IN VITRO
SEE IMMUNOLOGY, SEROLOGY*
ANTIGENS
SEE IMMUNOLOGY, ANTIGENS
ANTIGENS BACTERIAL
SEE IMMUNOLOGY, ANTIGENS BACTERIAL
ANTIGENS FUNGAL
SEE IMMUNOLOGY. ANTIGENS FUNGAL
ANTIGENS HELMINTHIC
SEE IMMUNOLOGY. ANTIGENS HELMINTHIC
ANTIGENS NEOPLASTIC
SEE NEOPLASMS IMMUNOLOGY, TUMOR ANTIGENS
ANTIGENS VIRAL
SEE IMMUNOLOGY. ANTIGENS VIRAL
ANTIGOUT DRUGS
SEE PURINESPYRIMIDINES METABOLISM ERRORS, GOUT
DRUGS
ANTI-H BLOOD GROUP (BOMBAY)
SEE BLOOD GROUPS, BOMBAY
•Excludes routine methodology OR covers only general projects which preclude indexing
'Oriented significantly to above subject.
at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
(contd)
;«^
ANT
ANTIHEMOPHILIC FACTOR
Slf BlOOn COACUIAIION, lACIOR VIII
ANTIHEMOPHILIC FACTOR A
Sff BlOOn COACmAIION (ACIOR VIII
ANTIHEMOPHILIC FACTOR B
Sri BlOOn C0A(UIIA1I0N t ACIOR IX
ANTIHEMOPHILIC FACTOR C
Sfi BIOOD COACIIIAIION, (ACTOR XI
ANTIHEMOPHILIC GLOBULIN
SEE BLOOD COAGUIAIION. FACTOR VIII
ANTIHISTAMINES
Stf HYPERSENSITIVITY. ANTIALIERGY DRUGS. HISTAMINE
ANTAGONISTS
ANTIHYPERTENSIVE AGENTS
SEE CAROIOVASCUUR AGENTS. ANTIHYPERTENSIVE AGENTS
ANTIINFECTIVE AGENTS
SEE COMMUNICABlt DISEASE CONTROL AGENTS
ANTIINFECTIVE AGENTS, ANTIBACTERIAL
SEE COMMUNICABLE DISEASE CONTROL AGENTS.
ANTIBACTERIAL
ANTIINFLAMMATORY AGENTS
SEE DISEASES. PATHOLOGIC PROCESSES. INFUMMATION.
ANTMNFUMMATORY AGENTS
ANTILEUKOCYTIC SERA
SEE IMMUNITY. IMMUNOSUPPRESSION. ALLOANTISERA.
ANTILEUKOCYTIC
ANTILYMPHOCYTIC SERA
SEE IMMUNITY. IMMUNOSUPPRESSION. ALLOANTISERA.
ANTILEUKOCYTIC
ANTIMALARIALS
SEE COMMUNICABLE DISEASE CONTROL AGENTS.
ANTIMALARIALS
ANTIMETABOLITES
SEE ALSO ANTIBIOTICS
SEE ALSO ANTIMITOTIC AGENTS
SEE ALSO ENZYME INHIBITORS
SEE ALSO NEOPLASTIC THERAPY. ANTINEOPLASTIC AGENTS
SEE ALSO THYROID ANTAGONISTS
R01HL1190611 Comparative study nf heart function
(cats. rats, hedgehogs, squirrels)
R01HL1561905 Regulation of prothrombin synthesisin
cultured cells (rats)
POlHL-1973702 0011 Cellular and molecular aspects of
respiratory physiology ■ Chemical and metabolic factors on
peripheral chemoreceptor activity (cats)
R23HL-21853-01 Lung metabolism and alveolo-capillaiy
permeability (rats)
ROlHL-22873-01 Adrenoceptor interconversion and
hormone homeostasis
ANTIMETABOLITES, ANTINEOPLASTIC
SEE NEOPLASTIC THERAPY. ANTINEOPLASTIC AGENTS
ANTIMICROBIAL AGENTS
SEE COMMUNICABLE DISEASE CONTROL AGENTS
ANTIMITOTIC AGENTS
SEE ALSO ANTIMETABOLITES
POlHL-16387-04 0003 The blood vessel and
thrombogenesis - Blood vessel healing (rabbits)
R01HL-1643705 Drug treatment of atherosclerosis
(rabbits, monkeys)
R01HL-20826-02 Megakaryocyte proliferation and its
control (mice)
ANTIMUSCARINIC AGENTS
SEE NEUROPHARMACOLOGICAL AGENTS,
PARASYMPATHOLYTIC
ANTIMYCOTIC AGENTS
SEE COMMUNICABLE DISEASE CONTROL AGENTS.
ANTIFUNGAL
ANTINEOPLASTIC AGENTS
SEE NEOPLASTIC THERAPY. ANTINEOPUSTIC AGENTS
ANTINEOPLASTIC ANTIBIOTICS
SEE ANTIBIOTICS. ANTINEOPLASTIC ANTIBIOTICS (GENERAL)
ANTIOXIDANTS
SEE OXIDANTS. ANTIOXIDANTS
ANTiPARKINSON DRUGS
SEE NEUROPHARMACOLOGICAL AGENTS. ANTIPARKINSON
DRUGS
ANTIPERNICIOUS ANEMIA PRINCIPLE
SEE VITAMIN B12
ANTIPYRETICS
SEE NEUROPHARMACOLOGICAL AGENTS. ANALGESICS.
ANTIPYRETICS
ANTIRENIN
SEE PEPTIDES. VASOACTIVE PEPTIDES. ANTIRENIN
I /
ANTIRHEUMATIC AGENTS
SI I CDNNIl IIVI IISSUI DISUHDIK". Hill UMAIlt
DISOHDIHS. ANIIRHIUMAIIC AGENTS
ANTISPASMODICS
Sff MUSCll RflAXANTS. ANTISPASMODICS
ANTITHROMBIN
SFI BIOOD COAGUIATION. ANTITHROMBIN
ANTITHROMBIN I
SIE BLOOD COAGUIATION. fIBRIN
ANTITHROMBIN II
SEE BIOOD COAGUIATION. HEPARIN CO FACTOR
ANTITHROMBOGENIC SURFACE
SEE BLOOD COAGUIATION. ANTITHROMBOGENIC SURFACE
ANTITHYMOCYTIC SERA
SEE IMMUNITY, IMMUNOSUPPRESSION. ALLOANTISERA,
ANTILEUKOCYTIC
ANTITHYROID COMPOUNDS
SEE THYROID ANTAGONISTS
ANTITOXINS
SEE IMMUNOLOGY. ANTITOXINS
ANTITRYPSIN DEFICIENCY
SEE METABOLIC DISORDERS (INBORN), ANTITRYPSIN
DEFICIENCY
ANTITRYPSIN INHIBITORS
SEE ENZYME INHIBITORS. TRYPSIN INHIBITORS. ANTITRYPSIN
ALPHA-1 -ANTITRYPSIN INHIBITORS
SEE ENZYME INHIBITORS. TRYPSIN INHIBITORS. ANTITRYPSIN
ANTIVIRAL AGENTS
SEE COMMUNICABLE DISEASE CONTROL AGENTS, ANTIVIRAL
ANTIVIRAL ANTIBODIES
SEE IMMUNOLOGY, ANTIBODIES VIRAL
ANTIVITAMINS
SEE VITAMIN ANTAGONISTS
ANURIA
SEE KIDNEY DISORDERS. ANURIA
ANXIETY
SEE PSYCHOLOGY. EMOTIONS. ANXIETY
AORTA
SEE CAROIOVASCUUR SYSTEM. ARTERIES. AORTA
AORTA COARCTATION
SEE CARDIOVASCULAR DISORDERS, AORTA OBSTRUCTIONS,
AORTA COARCTATION
AORTA DISORDERS (GENERAL)
SEE CARDIOVASCULAR DISORDERS, AORTA DISORDERS
(GENERAL)
AORTA OBSTRUCTION
SEE CAROIOVASCUUR DISORDERS, AORTA OBSTRUCTIONS
AORTIC ANEURYSM
SEE CAROIOVASCUUR DISORDERS, AORTIC ANEURYSM
AORTIC BALLOON PUMPING
SEE HEART PROSTHESIS. AUXILIARY, AORTIC BALLOON
PUMPING
AORTIC BODY
SEE NERVOUS SYSTEM, PARAGANGLIA, AORTIC BODY
AORTIC INSUFFICIENCY
SEE HEART DISORDERS, VALVULAR INSUFFICIENCY, AORTIC
INSUFFICIENCY
AORTIC VALVE
SEE HEART, VALVES, AORTIC VALVE
AORTIC VALVE DISORDERS
SEE HEART DISORDERS, VALVULAR, AORTIC VALVE
DISORDERS
AORTIC VALVE STENOSIS
SEE HEART DISORDERS, VALVULAR. AORTIC VALVE STENOSIS
AOTES
SEE MAMMALS. PRIMATES. MONKEYS AND APES
(ANTHROPOIDS, NON-HUMAN), NEW WORLD MONKEYS
(PLATYRHINES)*
APC AGENTS
SEE VIRUSES, ADENOVIRUSES
APLASTIC ANEMIA
SEE BLOOD AND RE DISORDERS, ANEMIA APUSTIC
APLASTIC ANEMIA CONGENITAL
SEE BLOOD AND RE DISORDERS, ANEMIA APUSTIC
CONGENITAL
APNEA
SEE RESPIRATORY FUNCTION, APNEA
APOENZYMES
SEE ENZYMES, APOENZYMES
APOPLEXY
Ml (.IRFBROVASCUIAR DISORDFRS, SIROKF
APPENDAGES
M I '.Kill lAI ',Y',IIM IIMH
APPETITE DEPRESSANTS
Ml NIIIHIINI INIAKI Al.llVliy ACCdIK 01 I'd ','.ANC,
APPETITE REVERSING FACTOR, PITUITARY
Ml lll'll) M(|I)III/IN(, lAr.KlM', PIMIIIAKY
APPLIED PHYSIOLOGY AND ORTHOPEDICS
STUDY SECTION
SEE PHYSIOIOCY (APPII(D) AND ORTHOPEDIC, STUDY
SECTION
APPOINTMENTS AND VISITS (PATIENTS)
SEE HFAITH CARF (SfRVICf S)(RESOURCFSI UTIIIZAIION.
APPOINIMFNIS VISITS
AQUATIC BIOLOGY
SEE WATER FNVIHONMENI, AOUAIIC BIOLOGY
AQUATIC ORGANISMS, FRESH WATER
SEE WATER ENVIRONMENT, AQUATIC ORGANISMS. FRESH
WATER-
AQUEOUS HUMOR
SEE EYE, AQUEOUS HUMOR
AQUEOUS SOLUTIONS
SEE PHYSICAL PROPERTIES, SOLUTIONS, AQUEOUS
ARA-C
SEE PYRIMIDINE NUCLEOSIDES, CYTOSINE NUCLEOSIDES.
CYTOSINE ARABINOSIOE
ARACHIDONIC ACID
SEE FAHY ACIDS, ARACHIDONIC ACID
ARACHNIDISM
SEE TOXICOLOGY, ANIMAL POISONS, ARTHROPOD, SPIDER
ARACHNODACTYLY
SEE METABOLIC DISORDERS INBORN, MARFAN SYNDROME
ARBOVIRUSES (GENERAL)
SEE VIRUSES, ARBOVIRUSES (GENERAL)
ARO AGENTS
SEE VIRUSES, ADENOVIRUSES
AREA POSTREMA
SEE BRAIN, MEDULU OBLONGATA, AREA POSTREMA
AREAWIDE MEDICAL PLANNING
SEE HEALTH CARE (SERVICES)(RESOURCES)PLANNING,
REGIONAL MEDICAL PUNNING
ARENAVIRUSES
SEE VIRUSES, ARENAVIRUSES
ARGENTAFFINOMA
SEE NEOPUSMS OF NERVOUS SYSTEM, CARCINOID
ARGININE
SEE DIAMINO ACIDS, ARGININE
ARGININE ESTERASE
SEE CARBOXYLIC ESTER HYOROUSES, ARGININE ESTERASE
ARGININE VASOPRESSIN
SEE PITUITARY-DIENCEPHALON HORMONES, VASOPRESSIN.
ARGININE VASOPRESSIN
ARM
SEE SKELETAL SYSTEM. LIMB. ARM
AROUSAL
SEE PSYCHIC ACTIVITY LEVEL. AROUSAL
ARRHYTHMIA, CARDIAC
SEE HEART DISORDERS. ARRHYTHMIA
ARRHYTHMIC AGENTS
SEE CAROIOVASCUUR AGENTS. ARRHYTHMIC AGENTS
ARTERENOL
SEE PHENYULKYUMINES. CATECHOUMINES.
NOREPINEPHRINE
ARTERIAL FIBROSIS
SEE HEART DISORDERS. CORONARY FIBROSIS
ARTERIAL INFUSIONS
SEE DOSAGE AND ROUTE. INFUSIONS ARTERIAL
ARTERIAL OCCLUSIONS
SEE CAROIOVASCUUR DISORDERS. ARTERIAL OCCLUSIONS
ARTERIES
SEE CAROIOVASCUUR SYSTEM. ARTERIES
ARTERIAL STENOSIS
SEE CAROIOVASCUUR DISORDERS, ARTERIAL STENOSIS
ARTERIOLES
SEE CAROIOVASCUUR SYSTEM, ARTERIOLES
ARTERIOSCLEROSIS
SEE CAROIOVASCUUR DISORDERS, ARTERIOSCLEROSIS
(contd)
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
ART
ARTERIOVENOUS ANASTOMOSIS NORMAL
SEE CARDIOVASCULAR SYSTEM, ARTERIOVENOUS
ANASTOMOSIS NORMAL
ARTERIOVENOUS SHUNTS ABNORMAL
SEE CARDIOVASCULAR DISORDERS, ARTERIOVENOUS SHUNTS
ABNORMAL
ARTERIOVENOUS SHUNTS SURGICAL
(GENERAL)
SEE CARDIOVASCUUR SURGERY, CARDIOVASCUUR SHUNTS
ARTERIOVENOUS (GENERAL)
ARTERITIS
SEE CARDIOVASCULAR DISORDERS, ARTERITIS
ARTHRITIS
SEE SKELETAL DISORDERS, ARTHRITIS
ARTHRITIS, RHEUMATOID
SEE SKELETAL DISORDERS, ARTHRITIS. RHEUMATOID
ARTHRITIS AND METABOLIC DISEASES
PROGRAM PROJECT COMMITTEE
R01HL19082-01 Hypoxia-induced relaxation of vascular
smooth muscle
ARTHROPOD BITES, STINGS, VENOMS
SEE TOXICOLOGY, ANIMAL POISONS, ARTHROPOD
ARTHROPOD-BORNE VIRUSES (GENERAL)
SEE VIRUSES, ARBOVIRUSES (GENERAL)
ARTHROPODS, CRUSTACEANS*
POlHL-0789615 0060 Environmental biomedical research
program - Effect of pressure on development of marine
crustacean larvae
ARTHROPODS, INSECTS, DIPTERA, CULICIDS,
MOSQUITOES*
POlHL-0821415 0023 Chemical and biological properties
of lipids - Lipids in microorganisms and cell cultures
(hamsters, mosquitoes)
ARTIFICIAL BLOOD
SEE BLOOD SUBSTITUTES
ARTIFICIAL INTELLIGENCE
SEE COMPUTER, ARTIFICIAL INTELLIGENCE, PATTERN
RECOGNITION AND CONTROL SYSTEMS
ARTIFICIAL KIDNEY
SEE KIDNEY PROSTHESIS, ARTIFICIAL KIDNEY
ARTIFICIAL LUNG
SEE RESPIRATORY SYSTEM PROSTHESIS, PROSTHETIC LUNG
ARTIFICIAL LUNG, MECHANICAL
SEE RESPIRATORY ASSIST AND OXYGEN ADMINISTRATION
RESPIRATORS
ARTIFICIAL RESPIRATION
SEE RESPIRATORY ASSIST AND OXYGEN ADMINISTRATION,
ARTIFICIAL RESPIRATION
ARTIFICIAL TISSUES
SEE PROSTHETIC ORGANS AND TISSUES
ARYL AMINO ACIDS
SEE CYCLIC AMINO ACIDS
ARYL HYDROCARBON HYDROXYLASE
SEE OXYGENASES, HYDROXYLASES, ARYL HYDROCARBON
HYDROXYLASE
ASBESTOS
SEE SILICATES, ASBESTOS
ASCARIS
SEE HELMINTHS, NEMATODES, ASCARIS
ASCHOFF BODIES
SEE HEART DISORDERS, MYOCARDITIS
ASCITES
SEE BODY CAVITY DISORDERS, PERITONEAL EFFUSIONS,
ASCITES
ASCITES TUMORS
SEE NEOPLASMS, ASCITES TUMORS
ASCORBIC ACID, ASCORBATE
SEE VITAMIN C
ASCORBIC ACID DEFICIENCY
SEE NUTRITIONAL ABNORMALITIES, HYPOVITAMINOSIS C
ASPARAGINE
SEE DICARBOXYLIC AMINO ACIDS, ASPARAGINE
ASPARTASE
SEE AMMONIALYASES, ASPARTASE
ASPARTATE TRANSAMINASE
SEE AMINOTRANSFERASES, ASPARTATE TRANSAMINASE
ASPARTATE TRANSCARBAMYLASE
SEE TRANSCARBAMYUSES, ASPARTATE TRANSCARBAMYLASE
ASPARTIC ACID
SEE DICARBOXYLIC AMINO ACIDS, ASPARTIC ACID
IS
ASPERGILLOSIS
SEE MYCOSES, ASPERGILLOSIS
ASPHYXIA, ACCIDENTAL
SEE INJURIES, ACCIDENTS, SUFFOCATION
ASPIRATION PNEUMONIA
SEE RESPIRATORY DISORDERS, PNEUMONIA ASPIRATION
ASPIRIN
SEE PHENYLCARBOXYUTES, SALICYLATES, ACETYL-
ASSAY
SEE BIOASSAY*
ASSISTED CIRCULATION
SEE CARDIOVASCULAR SURGERY. CIRCULATORY ASSIST
ASSOCIATIONS, HEALTH AND SCIENTIFIC
SEE HEALTH AND SCIENTIFIC ORGANIZATIONS
ASTHAAA
SEE HYPERSENSITIVITY, RESPIRATORY HYPERSENSITIVITY
ASTHMA
ASYMMETRIC SEPTAL HYPERTROPHY
SEE CONGENITAL ABNORMALITIES, HEART DEFECTS
ASYMMETRIC SEPTAL HYPERTROPHY
ATARAXIC DRUGS
SEE PSYCHOPHARMACOLOGICAL AGENTS, TRANQUILIZERS
ATELECTASIS
SEE RESPIRATORY DISORDERS, ATELECTASIS
ATELES
SEE MAMMALS, PRIMATES, MONKEYS AND APES
(ANTHROPOIDS, NON-HUMAN), NEW WORLD MONKEYS
(PLATYRHINES)*
ATHEROSCLEROSIS
SEE CARDIOVASCULAR DISORDERS, ARTERIOSCLEROSIS
ATHEROSCLEROSIS
ATLASES
SEE PUBLICATIONS, ATLASES
ATMOSPHERE
SEE ENVIRONMENT, ATMOSPHERE (WEATHER)
ATMOSPHERIC PRESSURE
SEE ENVIRONMENT, ATMOSPHERIC PRESSURE
ATOMIC ABSORPTION SPECTROMETRY
SEE CHEMISTRY, ANALYTICAL METHODS, SPECTROMETRY
ATOMIC ABSORPTION*
ATOMIC ORBITALS
SEE ELECTRONIC SPECTRA, ATOMIC ORBITALS
ATOPY
SEE HYPERSENSITIVITY, ATOPY
ATP
SEE PURINE NUCLEOTIDES, ADENINE NUCLEOTIDES, ATP
ATP:AMP PHOSPHOTRANSFERASE
SEE PHOSPHOTRANSFERASES, ATP:AMP
PHOSPHOTRANSFERASE
ATPASE
SEE PHOSPHATASES. ADENOSINE TRIPHOSPHATASE
ATP:CREATINE PHOSPHOTRANSFERASE
SEE PHOSPHOTRANSFERASES. ATP:CREATINE
PHOSPHOTRANSFERASE
ATP:DIGLYCERIDE PHOSPHOTRANSFERASE
SEE PHOSPHOTRANSFERASES, ATP;OIGLYCERIDE
PHOSPHOTRANSFERASE
ATP:D-FRUCTOSE-6-PHOSPHATE 1-
PHOSPHOTRANSFERASE
SEE PHOSPHOTRANSFERASES. ATP:D-FRUCT0SE-6-PH0SPHATE
1-PHOSPHOTRANSFERASE
ATP:D-3-PHOSPHOGLYCERATE 1-
PHOSPH OTRANSFERASE
SEE PHOSPHOTRANSFERASES. ATP:D-3-PH0SPH0GLYCERATE
1-PHOSPHOTRANSFERASE
ATP PHOSPHOHYDROLASE
SEE PHOSPHATASES. ADENOSINE TRIPHOSPHATASE
ATP:PHOSPHORYLASE PHOSPHOTRANSFERASE
SEE PHOSPHOTRANSFERASES. ATP:PHOSPHORYUSE
PHOSPHOTRANSFERASE
ATP:PROTEIN PHOSPHOTRANSFERASE
SEE PHOSPHOTRANSFERASES. ATPiPROTEIN
PHOSPHOTRANSFERASE
ATP:THYMIDINE 5-PHOSPHOTRANSFERASE
SEE PHOSPHOTRANSFERASES, ATPJHYMIDINE 5-
PHOSPHOTRANSFERASE
ATRIA
SEE HEART, ATRIA
ATRIAL FIBRILLATION
SEE HEART DISORDERS, ARRHYTHMIA, ATRIAL FIBRILLATION
•Ficludes routine methodology OR covers only general projects which preclude indexing at the specific level
'^•■jn?,' 'p, nif icantly to above subject.
M Grant has subprojects describing specific research aspects
See Appendix for invettlgator's name end grant number.
AUT
ATRIOVENTRICULAR BLOCK
SEE HEART DISORDERS, ARRHYTHMIA. HEART BLOCK
ATRIOVENTRICUUR
ATRIOVENTRICULAR NODE
SEE HEART. CONDUCTION SYSTEM. ATRIOVENTRICULAR NODE
ATRIUM
SEE HEART. ATRIA
ATROPINE
SEE TROPANES. ATROPINE
ATROPINESTERASE
SEE CARBOXYLIC ESTER HYOROUSES. CARBOXYLESTERASE
ATTENTION
SEE PSYCHIC ACTIVrfY LEVEL. AHENTION
ATTITUDE TO HEALTH AND HEALTH PROBLEMS
SEE PSYCHOLOGY, AHITUDE TO HEALTH AND HEALTH
PROBLEMS
ATTITUDES
SEE PSYCHOLOGY, ATTITUDES (AND REUTEO)
ATTITUDES OF PATIENT CARE PERSONNEL
SEE HEALTH CARE SERVICES, PATIENT CARE PERSONNEL
ATTITUDES
ATYPICAL PNEUMONIA (PPLO)
SEE RESPIRATORY DISORDERS, PNEUMONIA MYCOPUSMAL
(PPLO)
AUDIOMETRY
SEE EAR DISORDERS DIAGNOSIS, HEARING TESTS
AUDIOMETRY*
AUDIOVISUAL AIDS
SEE EDUCATION, AUDIOVISUAL AND OTHER TRAINING AIDS
AUDITORY CORTEX
SEE BRAIN, AUDITORY CORTEX
AUDITORY THRESHOLDS
SEE EAR, HEARING, AUDITORY THRESHOLD
AURICLES, HEART
SEE HEART, ATRIA
AUSTRALIAN ANTIGEN (AUA)
SEE IMMUNOLOGY, ANTIGENS VIRAL. HEPATITIS B ANTIGEN
(HBAG)
AUTOANTIBODIES
SEE IMMUNOPATHOLOGY, AUTOANTIBODIES
AUTOANTIGENS
SEE IMMUNOPATHOLOGY. AUTOANTIGENS
AUTOFLUOROSCOPY
SEE RADIOGRAPHY, FLUOROSCOPY. AUTOFLUOROSCOPY*
AUTOGENIC CONDITIONING (TRAINING)
SEE PSYCHOLOGY. CONDITIONING. AUTOGENIC AND INTERNAL
CONTROL
AUTOIAAMUNE DISORDERS
SEE IMMUNOPATHOLOGY. AUTOIMMUNE DISORDERS
AUTOIMMUNE HEMOLYTIC ANEMIA
SEE BLOOD AND RE DISORDERS. ANEMIA HEMOLYTIC
AUTOIMMUNE
AUTOMATED ANALYTICAL PROCESSING AND
CONTROL SYSTEMS
SEE BIOMEDICAL SYSTEMS AUTOMATED
AUTOMATED BIOMEDICAL FACILITIES
SEE BIOMEDICAL SYSTEMS AUTOMATED
AUTOAAATED HEALTH RECORDS (SYSTEMS)
SEE HEALTH RECORDS (SYSTEMS) AUTOMATED
AUTOMATIC DATA PROCESSING
SEE INFORMATION AND COMMUNICATION. AUTOMATIC DATA
PROCESSING
AUTONOMIC AGENTS
SEE NEUROPHARMACOLOGICAL AGENTS. AUTONOMIC AGENTS
AUTONOMIC CONDITIONING
SEE PSYCHOLOGY. CONDITIONING. AUTOGENIC AND INTERNAL
CONTROL
AUTONOMIC GANGLIA
SEE NERVOUS SYSTEM AUTONOMIC. AUTONOMIC GANGLIA
AUTONOMIC NERVOUS DYSFUNCTION
FAMILIAL
SEE CONGENITAL ABNORMALITIES. NEUROLOGICAL
DYSAUTONOMY FAMILIAL
AUTONOMIC NERVOUS SYSTEM
SEE NERVOUS SYSTEM AUTONOMIC
AUTONOMIC NERVOUS SYSTEM DISORDERS
SEE NERVOUS DISORDERS AUTONOMIC (GENERAL)
AUTONOMIC REFLEXES
SEE NERVOUS SYSTEM AUTONOMIC, AUTONOMIC REFLEXES
(contd)
AUT
1 ')
AUTONOMY, EMOTIONAL
Sa PSYCHOIOCY, [MOIIONAl Dll'INOl NCY INOl PI NOt NCY
AUTO-OXIDATION
SF( nXIDAIIONREDUCIION. AllIO OXinAIIQN
AUTOPHAOY
St I cm OFSTRUCIION. AUIOPHACY
AUTOPROTHROMBIN I
Sri BIOOO COAGUIAIION. FACIOR VII
AUTOPROTHROMBIN II
Sff BLOOO COAGUIAIION. FACIOR IX
AUTOPROTHROMBIN III
SFF BLOOD COAGUIAIION. FACIOR X
AUTORADIOGRAPHY
SEE RADIOAUIOGRAPHY*
AUTOSENSITIZATION
SEE IMMUNOPAIHOLOGY. AUTOIMMUNE DISORDERS
AUTOSOMAL RECESSIVE CONDITIONS
SEE GENETIC DISORDERS. AUTOSOMAL RECESSIVE
CONDITIONS
AUTOTRANSFUSION
SEE BLOOO TRANSFUSION, AUTOTRANSFUSION
AUTOTRANSPLANTATION
SEE TISSUE COMPATIBILITY TRANSPLANT. TRANSPLANTATION
AUTOLOGOUS
AUXILIARY HEALTH (CARE) PERSONNEL
SEE HEALTH SCIENCES PROFESSIONS. HEALTH (CARE)
PERSONNEL ALLIED
AUXIUARY HEART PROSTHETIC
SEE HEART PROSTHESIS. AUXILIARY
AUXILIARY MENTAL HEALTH PERSONNEL
SEE MENTAL HEALTH PERSONNEL ADJUNCT
AUXILIARY VENTRICLE, BALLOON PUMP AORTIC
SEE HEART PROSTHESIS. AUXILIARY, AORTIC BALLOON
PUMPING
A-V NODE
SEE HEART. CONDUCTION SYSTEM. ATRIOVENTRICULAR NODE
AVAILABILITY AND DISTRIBUTION OF HEALTH
CARE SERVICES AND RESOURCES
SEE HEALTHCARE (SERVICESXRESOURCES) UTILIZATION.
AVAILABILITY AND DISTRIBUTION OF SERVICES AND
RESOURCES
AVIAN NEUROLYMPHOMATOSIS
SEE NERVOUS DISORDERS CENTRAL, MAREK'S DISEASE
AVIATION MEDICINE
SEE ENVIRONMENT. EXTRATERRESTRIAL, SUPRATERRESTRIAL
AVOIDANCE CONDITIONING
SEE PSYCHOLOGY, CONDITIONING, AVOIDANCE
AXONS
SEE NERVOUS SYSTEM. NEURONS. AXONS
AXOPLASMIC FLOW
SEE NERVOUS SYSTEM. NEURONS, AXOPLASMIC FLOVK
1 0-AZAANTHRACENE
SEE ACRIDINES
1 -AZABICYCLO(2.3.2)OCTANES
SEE QUINUCLIDINES
AZACYTIDINE
SEE TRIAZINE NUCLEOSIDES, AZACYTIDINE
AZATHIOPRINE
SEE THIOPURINES, 6-MERCAPTOPURINE, AZATHIOPRINE
AZEPINES, DESIPRAMINE
ROlHL-15758-06 Catecholamine release in the heart
(dogs)
ROlHL-1643604 Role of calcium and thyroxine in heart
function (rats)
AZEPINES, DIAZEPAM
POlHL-12738-10 0042 Physiologic pharmacology and its
clinical applications - Centrogenic cardiac arrhythmias
(cats)
POlHL-14388-07 0159 Regulation of the circulation in
pathological states - Early drug and diet Interventions and
blood pressure development (rats)
R0IHL1795804 Circulatory effects of operant
cardiovascular control (baboons)
POlHL-18576-03 0007 Thrombosis research program
project - Relationships between coagulability and
thrombosis (human, animals)
AZEPINES, DIAZEPINES
P60HL1 7269-04 0016 National heart and blood vessel
research and demonstration center - New analytical
methodology for atherosclerosis studies
AZEPINES, DIAZEPINES, CHLORDIAZEPOXIDE
POIIII I2/J8 10 004? Phytiologic phtrmacolony ond \\\
clinicil applications Cfntro|tnic cardiac arihythmiat
(cats)
AZEPINES, DIAZEPINES, FLURAZEPAM
PUIIII I49HSU/ UOO'J AdiipUlioii lu hypoiia Inlluencc
of chemosensitivity on control ul brc;ithin|i duiing sleep
(human, dogs)
AZEPINES, IMIPRAMINE
R?3Hl I9S73 0I Studies on pulmondiy serotonin (mice)
ROIHL ?0622 0? Pulmonary uptake and accumulation of
diugs (rabbits, rats)
AZETIDINE
ROIHL 1913603 Mucopolysacchtrid* metabolism in
cardiac anomalies (rats)
AZIDES
ROIHL 12524 10 Reaction ol hemoglobin with ligsnds and
antibodies (human, carp)
ROIHL 16860 OS Mossbauer studies of respiratory
hemoproteins
AZO (AZINO) COMPOUNDS
SEE ALSO AZIDES
ROIHL 13412 17 Synthetic oxygen carriers
AZO COMPOUNDS, HYDRAZINES, ISONIAZID
POIHL 12738 10 0001 Physiologic pharmacology and its
clinical applications Clinical pharmacology of cardioactive
drugs (human)
AZO COMPOUNDS, HYDRAZINES, PHENELZINE
POIHL'12738 10 0001 Physiologic pharmacology and its
clinical applications Clinical pharmacology of cardioactive
drugs (human)
AZO COMPOUNDS, HYDRAZINES,
PHENYLHYDRAZINES
ROIHL 19532 01 Oxygen toxicity in the red cell (human)
AZO COMPOUNDS, HYDRAZINOPHTHALAZINE
*• POlHL-06312 17 0016 Surgical cardiology ■ Effect of
hydialazine on inlarct size following coronary occlusion
(human)
POlHL-06835-17 0037 Cardiovascular disease - Cardiac
hypertrophy in spontaneously hypertensive rat
P01HL06835-17 0053 Cardiovascular disease ■
Vasodilating drugs (human)
P01HL06835'17 0057 Cardiovascular disease - Studies
on cardiac hypertrophy
Physiologic pharmacology and its
Clinical pharmacology of cardioactive
Physiologic pharmacology and its
Cardiovascular pharmacology (dogs)
Regulation of the circulation in
Kallikrein-kinin system in hypertension
POIHL 12738 10 0001
clinical applications
drugs (human)
POlHL-12738-10 0111
clinical applications
P01HL1438807 0223
pathological states
(rats)
ROlHL'15047-06 Digital computer analysis of the
electrocardiogram (human)
ROlHL-1775403 Pathogenesis and prevention of
hypertension sequelae (rats)
ROlHL-18579-03 Vasoactive hormones and blood pressure
regulation (dogs. rats, rabbits)
P50HL19362-02 0010 A/S SCOR -Atherosclerosis in
nonhuman primates - Antihypertensive therapy -
Atherogenesis in experimental hypertension (baboon)
ROlHL-1966803 Biochemistry of lung connective tissue
(rats)
POlHL-20552-02 0002 The development and regression of
cardiac hypertrophy - Effect of treatment on the
hypertrophied left ventricle (rats)
ROlHL-227 18-01 Cardiovascular drug interactions-
Metabolism models (dogs)
AZO DYES
SEE AZO (AZINO) COMPOUNDS
AZOPROTEINS
ROlHL-13399-16 Heme protein structure and function
(human, horse, plants, bacteria)
BABOONS
SEE MAMMALS. PRIMATES, MONKEYS AND APES
(ANTHROPOIDS, NON-HUMAN), OLD WORLD MONKEYS
(CATARRHINES)*
BACILLUS CALMETTE-GUERIN
SEE BACTERIA, ACTINOMYCETALES, BACILLUS CALMETTE-
GUERIN*
BACILLUS PILIFORMIS
SEE BACTERIA, GRAM-NEGATIVE*
BACITRACIN
SEE ANTIBIOTICS, BACITRACIN
BACTEREMIA
SEE BLOOD TOXICOLOGY, BACTEREMIA-SEPTICEMIA
BACTERIA, ACID-FAST BACTERIA*
R01HL-07502-13 Phytochemistry of the genus thalictrum
(dogs, plants)
BACTERIA, ACTINOMYCETALES, BACILLUS
CALMETTE-GUERIN*
KUIIII 2II2UU2 Mtmbiana dynamics in alveolii
macrophages (rabbits)
ROIIII 7230I 01 Immunogenetics of chionic pulmonary
inflarnmalion (micfl)
BACTERIA, ACTINOMYCETALES,
MYCOBACTERIUM TUBERCULOSIS*
Sf( Also BACIIRIAI DIM AM ',, A(,IIN0MY(,1 lAllS
INFECTIONS, lUBFRCUIOSI'i
•• ROIHl 710950? Fn/ymrs o( M tuberculosis and
obstructive lung disease (human, rodent',)
BACTERIA. ACTINOMYCETALES, THERMOPHILIC
ACTINOMYCETES*
PbOHL 15389 07 001 1 Pulmonary SCOR HypaiMniitivity
pneumonitis Animal model Hypersensitivity pneumonitis
in rabbits
** P50HL 15389 0/ 0015 Pulmonary SCOR Hypersensitivity
pneumonitis Fractionation and characterization of
thermophilic Actinomycete antigens
P50HL 15389 07 0019 Pulmonary SCOR Hypersensitivity
pneumonitis Microbiology core (human, animal)
BACTERIA, ENTERIC (GENERAL)*
SEE ALSO BACTERIA. PSEUDOMONADALES. PSEUDOMONAS
AERUGINOSA*
SEE ALSO BACTERIA, STREPTOCOCCACEAE, STREPTOCOCCUS,
ENTEROCOCCUS GROUP*
** ROIHL 10894 12 Intestinal bacteria and steroid
metabolism (human, guinea pigs, rabbits, rats)
ROlHL-17818 05 Metabolism ol cholesterol and cholesterol
in man (also rats, monkeys)
** P50HL 19362-02 0009 A/S SCOR Atherosclerosis in
nonhuman primates Cholesterol metabolism and
intestinal microflora (baboon)
BACTERIA, ENTERIC, RUMEN BACTERIA*
** R01HL13645-11 Tryptophaninduced pulmonary
emphysema (cattle, goats, rabbits)
BACTERIA, ENTEROBACTERIACEAE, PROTEUS*
ROlHL-22029-02 Bronchopulmonary resistance to bacterial
infection (mice)
BACTERIA, ENTEROBACTERIACEAE, SERRATIA
MARCESCENS*
** POlHL-16769-05 0004 Pathobiologic and host defense
reactions in the lung - Pathogenesis of Pseudomonas and
Serratia pneumonias (rabbits)
BACTERIA, GRAM-NEGATIVE*
SEE ALSO BACTERIA. HALOBACTERIACEAE*
ROlHL-07502-13 Phytochemistry of the genus thalictrum
(dogs, plants)
BACTERIA, HALOBACTERIACEAE*
** POlHL-06285-18 0211 Cardiovascular-respiratory
physiology and biochemistry - Purple membrane of
Halobacteria
•* POlHL-06285-18 0213 Cardiovascular-respiratory
physiology and biochemistry - Membrane structure and
function -Gas vacuole membrane (Halobacterium)
BACTERIA, MICROCOCCACEAE,
STAPHYLOCOCCUS*
SEE ALSO BACTERIAL DISEASES, STAPHYLOCOCCAL
INFECTIONS
R01HL-I6646-05 Pathobiology of thromboembolic disorders
(human)
POlHL-16769-05 0004 Pathobiologic and host defense
reactions in the lung - Pathogenesis of Pseudomonas and
Serratia pneumonias (rabbits)
BACTERIA, MICROCOCCACEAE,
STAPHYLOCOCCUS AUREUS*
ROlHL-203 14-02 Host defense against S pheumoniae in
sickle cell disease (human)
ROlHL-22029-02 Bronchopulmonary resistance to bacterial
infection (mice)
BACTERIA, MICROCOCCACEAE,
STAPHYLOCOCCUS EPIDERMIDIS*
ROlHL-17751-03 Experimental endocarditis (rabbits)
BACTERIA, MYCOPLASMATALES, MYCOPLASMA*
ROlHL-19741-03 Murine CRD -A model of chronic
pulmonaiy inflammation (mice, rats)
BACTERIA, MYCOPLASMATALES, MYCOPLASMA
PNEUMONIAE*
SEE ALSO RESPIRATORY DISORDERS. PNEUMONIA
MYCOPLASMAL (PPLO)
P50HL-14136-07 0003 Pulmonary SCOR-Airways
obstructive diseases - Acute pediatric respiratory disease
and COLD
BACTERIA, NEISSERIACEAE, NEISSERIA
MENINGITIDIS*
P01HL-06350-17 0019 Hemostasis research program
project - Microcirculation (human, rats, rabbits)
(contd)
*Exclude$ routine methodology OR covers only general projects which preclude indexing at the specific level.
**Onented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
BAC
BACTERIA, PSEUDOMONADALES,
PSEUDOMONAS*
" ROlHL-13885-08 0007 Cystic fibrosis and pulmonary
disease ■ Alveolar macrophage defense mectianism
(human, rabbits)
BACTERIA, PSEUDOMONADALES,
PSEUDOMONAS AERUGINOSA*
POlHL-06314-17 0046 Immunologic mechanisms in
cardiovascular disease - Mediators of immune injury
(human, mice)
POlHL-06370-17 0013 Cardiopulmonary and renal
pathology research center ■ (Morphologic analysis of
vascular prosthesis (human, dogs)
ROIHL 13885-08 0006 Cystic fibrosis and pulmonary
disease - Cell mediated immunity and Pseudomonas
infections in cystic fibrosis (human)
R01HL13885-08 0007 Cystic fibrosis and pulmonary
disease - Alveolar macrophage defense mechanism
(human, rabbits)
R01HL13885 08 0008 Cystic fibrosis and pulmonary
disease - Pseudomonas specific activation of alveolar
macrophages (human, rabbits)
** POlHL-16769-05 0004 Pathobiologic and host defense
reactions in the lung - Pathogenesis of Pseudomonas and
Serratia pneumonias (rabbits)
POlHL-1676905 0008 Pathobiologic and host defense
reactions in the lung - Pulmonary immunocytologic defense
mechanisms against bacteria (human, animals)
P50HL-1915302 0003 SCOR-Pulmonary edemas-Eltology.
pathogenesis - Possible inhibitors of mediator release and
pulmonary vascular response (sheep)
R23HL-21212-02 Alveolar macrophage function in
Pseudomonas infection (dgs)
BACTERIA, STREPTOCOCCACEAE*
P50HL1421807 0005 Pulmonary SCOR-Nev»born lung
center ■ Prevention of infection in infants with respiratory
distress (human)
BACTERIA, STREPTOCOCCACEAE,
STREPTOCOCCUS*
SEE ALSO BACTERIAL DISEASES, STREPTOCOCCAL
INFECTIONS
** ROlHL-03919-20 The cell suface of streptococci (rats,
human)
BACTERIA, STREPTOCOCCACEAE,
STREPTOCOCCUS, ENTEROCOCCUS GROUP*
POlHL-0631417 0059 Immunologic mechanisms in
cardiovascular disease - Immunogenetic response to
streptococcal antigens in man
R01HL17751-03 Experimental endocarditis (rabbits)
BACTERIA, STREPTOCOCCACEAE,
STREPTOCOCCUS GROUP A*
SEE ALSO IMfVIUNOLOGY, ANTIGENS BACTERIAL,
STREPTOKINASE
ROlHL-01803-23 0001 Arteriosclerosis, glomerulonephritis,
rheumatic fever • Post-streptococcal glomerulonephritis
(rabbit)
POlHL-0631417 0060 Immunologic mechanisms in
cardiovascular disease ■ Strept antigens and infections in
cardiovascular complications (human, animals)
** R01HH9234-03 Streptococci and heart ■Cell-mediated
;ross-reaction (mice)
ROlHL-2053309 Pathogenesis of rheumatic fever (human,
rabbits)
BACTERIA, STREPTOCOCCACEAE,
STREPTOCOCCUS GROUP B*
POlHL-06314-17 0060 Immunologic mechanisms in
cardiovascular disease - Strept antigens and infections in
cardiovascular complications (human, animals)
BACTERIA, STREPTOCOCCACEAE,
STREPTOCOCCUS GROUP C*
POlHL-06314-17 0059 Immunologic mechanisms in
cardiovascular disease • Immunogenetic response to
streptococcal antigens in man
BACTERIA, STREPTOCOCCACEAE,
STREPTOCOCCUS PNEUMONIAE*
SEE ALSO VACCINES, BACTERIAL, PNEUMOCOCCAL VACCINE
POlHL-06350-17 0019 Hemostasis research program
project - Microcirculation (human, rats, rabbits)
P60HL-15169-05 0009 Support for center for sickle cell
disease - Infections in sickle cell anemia (human)
ROlHL-20314-02 Host defense against S pheumoniae in
sickle cell disease (human)
ROlHL-22029-02 Bronchopulmonary resistance to bacterial
infection (mice)
BACTERIAL ANTIBODIES
SEE IMMUNOLOGY. ANTIBODIES BACTERIAL
BACTERIAL ANTIGENS
SEE IMMUNOLOGY. ANTIGENS BACTERIAL
BACTERIAL ANTITOXINS
SEE IMMUNOLOGY. ANTITOXINS
BACTERIAL DISEASES
SEE ALSO BLOOD TOXICOLOGY, BACTEREMIA-SEPTICEMIA
20
SEE ALSO COMMUNICABLE DISEASE CONTROL AGENTS
ANTIBACTERIAL
SEE ALSO IMMUNOLOGY, ANTIBODIES BACTERIAL
SEE ALSO IMMUNOLOGY. ANTIGENS BACTERIAL
SEE ALSO NERVOUS DISORDERS CENTRAL, MENINGITIS
BACTERIAL
SEE ALSO RESPIRATORY DISORDERS, PNEUMONIA BACTERIAL
M POlHL-06314-17 Immunologic mechanisms in
cardiovascular disease
POlHL-063 14-17 0046 Immunologic mechanisms in
cardiovascular disease Mediators of immune injury
(human, mice)
** P50HL142 18-07 0005 Pulmonary SCOR-Nev»born lung
center - Prevention of infection in infants with respiratory
distress (human)
** P60HL-151 69-05 0009 Support for center for sickle cell
disease - Infections in sickle cell anemia (human)
P60HL 15996-06 0003 Cincinnati comprehensive sickle
cell center - Prophylactic penicillin in treatment of sickle
cell anemia (human)
P60HL-15996-06 0005 Cincinnati comprehensive sickle
cell renter - Factors precipitating crises (human)
ROlHL-19774-03 Pathogenesis of chronic lung disease
(rats, mice, bacteria)
ROlHL-22029-02 Bronchopulmonary resistance to bacterial
infection (mice)
BACTERIAL DISEASES, ACTINOMYCETALES
INFECTIONS, TUBERCULOSIS
SEE ALSO BACTERIA, ACTINOMYCETALES, MYCOBACTERIUM
TUBERCULOSIS*
P50HL141 53-07 0004 Johns Hopkins Lung Center
Chronic diseases of airways • Macrophage enzymes in lung
injury, inflammation and repair (rabbit)
BACTERIAL DISEASES, CYTOPATHOGENIC
EFFECT BACTERIAL
ROlHL-01803-23 0001 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Poststreptococcal glomerulonephritis
(rabbit)
R01HL19741-03 Murine CRD-A model of chronic
pulmonary inflammation (mice, rats)
ROlHL-20063-03 Pathogenesis of pulmonary mycoplasma
infections (guinea pigs, mice)
ROlHL-2017002 Pulmonary infection in splenectomized
animals (mice)
** ROlHL-20963-01 Experimental lung abscess (rabbits)
ROlHL-2252001 Pulmonary vascular response to group B
Streptococci (human, mammals)
BACTERIAL DISEASES, STAPHYLOCOCCAL
INFECTIONS
SEE ALSO BACTERIA. MICROCOCCACEAE, STAPHYLOCOCCUS*
SEE ALSO SKELETAL DISORDERS, OSTEOMYELITIS
** ROlHL-221 10-02 Healing complications in vascular
grafting (dogs)
BACTERIAL DISEASES, STREPTOCOCCAL
INFECTIONS
SEE ALSO BACTERIA, STREPTOCOCCACEAE,
STREPTOCOCCUS*
ROlHL-01803-23 0001 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Poststreptococcal glomerulonephritis
(rabbit)
ROlHL-01803-23 0018 Arteriosclerosis, glomerulonephritis,
rheumatic fever ■ Fetal immunization in pathogenesis of
glomerulonephritis in adult (rabbit)
** ROlHL-01803-23 0019 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Pathogenesis of rheumatic heart disease
(rabbit)
Immunologic mechanisms in
■ Antigens in cardiovascular disease
POlHL-063 14-17 0057
cardiovascular disease
(human)
POlHL-063 14-17 0059
cardiovascular disease
Immunologic mechanisms in
Immunogenetic response to
streptococcal antigens in man
** POlHL-06314-17 0060 Immunologic mechanisms in
cardiovascular disease ■ Strept antigens and infections in
cardiovascular complications (human, animals)
P60HL-15160-07 0014 Center for sickle cell disease -
Replacement therapy of opsonin deficiency in sickle cell
anemia (children)
** P60HL-15162-07 0021 Comprehensive sickle cell center ■
Pneumococcal vaccine in sickle cell disease (children)
** ROlHL-201 70-02 Pulmonary infection in splenectomized
animals (mice)
*♦ P60HL-20985-01 0002 Northern California sickle cell
center - Immunization with polyvalent pneumococcal
polysaccharide vaccine (human)
** ROlHL-22520-01 Pulmonary vascular response to group B
Streptococci (human, mammals)
P60HL-23282-01 0002 Comprehensive hospital/community
sickle cell center - Clinical evaluation of alternate
pathaway of compliment activation
BACTERIAL DISEASES, STREPTOCOCCAL
INFECTIONS, RHEUMATIC FEVER
SEE ALSO HEART DISORDERS, RHEUMATIC HEART DISEASE
ROlHL-039 19-20 The cell suface of streptococci (rats,
human)
** POlHL-063 14-17 0057 Immunologic mechanisms in
cardiovascular disease ■ Antigens in cardiovascular disease
(human)
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprajects describing specific research aspects.
See Appendix for investigator's name and grant number.
BAR
POlHL-063 14- 17 0060 Immunologic mechanisms in
cardiovascular disease ■ Strept antigens and infections in
cardiovascular complications (human, animals)
ROlHL-19234-03 Streptococci and heart -Cell-mediated
cross-reaction (mice)
ROlHL-1930703 Problems in prevention of rheumatic
heart disease (human)
ROlHL-20533-09 Pathogenesis of rheumatic fever (human,
rabbits)
BACTERIAL ENDOCARDITIS
SEE HEART DISORDERS, ENDOCARDITIS BACTERIAL
BACTERIAL MENINGITIS
SEE NERVOUS DISORDERS CENTRAL, MENINGITIS BACTERIAL
BACTERIAL PERMEASES
SEE BIOLOGICAL TRANSPORT, TRANSPORT PROTEINS
PERMEASES
BACTERIAL PNEUMONIA
SEE RESPIRATORY DISORDERS, PNEUMONIA BACTERIAL
BACTERIAL POLYSACCHARIDES
SEE POLYSACCHARIDES, BACTERIAL (GENERAL)
BACTERIAL PROTEINS
SEE PROTEINS, BACTERIAL (GENERAL)
BACTERIAL TOXINS
SEE IMMUNOLOGY, ANTIGENS BACTERIAL, BACTERIAL TOXINS
(GENERAL)
BACTERIAL VACCINES
SEE VACCINES, BACTERIAL (GENERAL)
BACTERICIDAL DEFENSES OF BODY (GENERAL)
SEE IMMUNITY. BACTERICIDAL DEFENSES (GENERAL)
BACTERICIDES
SEE COMMUNICABLE DISEASE CONTROL AGENTS
ANTIBACTERIAL
BACTERIOLOGY AND MYCOLOGY STUDY
SECTION
ROlHL-17751-03 Experimental endocarditis (rabbits)
ROlHL-19234-03 Streptococci and heart -Cell-mediated
cross-reaction (mice)
ROlHL-19307-03 Problems in prevention of rheumatic
heart disease (human)
ROlHL-19760-01 Cellular immune responses of the lung
(mice, guinea pigs)
ROlHL-19873-03 Pulmonary responses to inhaled antigen
(rabbits, guinea pigs)
ROlHL-20314-02 Host defense against S pheumoniae in
sickle cell disease (human)
R23HL-2121202 Alveolar macrophage function In
Pseudomonas infection (dgs)
ROlHL-22029-02 Bronchopulmonary resistance to bacterial
infection (mice)
ROlHL-22257-01 Leukokinesis enhancing factor and lung
infections (human, rats)
R23HL-22823-0I Phagocytic and immune defense
mechanisms of the lung (mice)
BACTERIOLYSIS
R23HL-21 116-02 Mechanisms of membrane and tissue
damage in lung (dogs, rabbits)
BACTERIORHODOPSIN
SEE PIGMENTS. BACTERIAL. BACTERIORHODOPSIN-RETINAL
BACTERIOTROPINS
SEE IMMUNOLOGY. ANTIBODIES. OPSONINS
BALLISTOCARDIOGRAPHY
SEE HEART DISORDERS DIAGNOSIS,
BALLISTOCARDIOGRAPHY*
BALLOON PUMPING, AORTIC
SEE HEART PROSTHESIS, AUXILIARY, AORTIC BALLOON
PUMPING
BANK, TISSUE
SEE TISSUE RESOURCES, REGISTRIES
BAPN
SEE CYANIDES, AMINOALKYL NITRILES, BAPN
BARBITURATES
SEE PYRIMIDINES, BARBITURATES
BARIUM (COMPOUNDS)
SEE METALS, ALKALINE EARTH METALS. BARIUM
BAROMETRIC DECOMPRESSION
SEE ENVIRONMENT. ATMOSPHERIC PRESSURE.
COMPRESSIONDECOMPRESSION
BAROPACER (CAROTID)
SEE HEART PACEMAKERS ELECTRONIC, CAROTID
STIMULATORS
BARORECEPTORS
SEE SENSE ORGANS, PRESSORECEPTORS
BARRIER MODEL
SEE BIOLOGICAL TRANSPORT, MEMBRANE MODELS
(contd)
BAS
BARHER'S SYNDROME
SH MIIAHOlir DISOKniKS INBORN BARnfRS SVNOKOMt
BASEMENT MEMBRANE
Sfl MIMHHANl, BASIMINI MIMHH»N1
BASEMENT MEMBRANE DISEASE OF LUNG AND
KIDNEY
SEE DISEASES. SYNDROMES NOI LISIEO ELSEWHERE.
GOODPASTURE S SYNDROME
BASES
SEE ACIDS BASES, BASES (GENEKAl)
BASES (NUCLEOSIDE, NUCLEOTIDE, NUCLEIC
ACID)
SEE NUCIEOBASES
BASOPHIL LEUKOCYTES
SEE BIOOD CEllS. LEUKOCYTES. BASOPHILS
BASSEN-KORNZWEIG SYNDROME
SEE MEIA80UC DISORDERS INBORN
HYPOLIPOPROTEINEMIAS fAMILIAL
ABETALIPOPROTEINEMIA
BATRACHOTOXIN
SEE TOXICOLOGY. ANIMAL POISONS. BATRACHOTOXIN
BCG
SEE BACTERIA. ACTINOMYCETALES. BACILLUS CALMEHE
GUERIN*
BEDDING FOR ANIMAL CARE
SEE ANIMALS. VETERINARY SCIENCE. ANIMAL CARE
BEHAVIOR
SEE PSYCHOLOGY, BEHAVIOR
BEHAVIOR, ANIMAL
SEE PSYCHOLOGY. BEHAVIOR ANIMAL
BEHAVIOR, MATERNAL
SEE FAMILY. MATERNAL BEHAVIOR
BEHAVIOR ASSESSMENT-MEASUREMENT
SEE PSYCHOLOGICAL TESTS. BEHAVIOR ASSESSMENT-
MEASUREMENT*
BEHAVIOR CONTROL
SEE PSYCHOLOGY, BRAIN CONTROL
BEHAVIOR MODIFICATION (PSYCHOTHERAPY)
SEE PSYCHOTHERAPY, BEHAVIOR MODIFICATION
BEHAVIOR PREDICTION
SEE PSYCHOLOGY, BEHAVIOR PREDICTION
BEHAVIOR RATING SCALES
SEE PSYCHOLOGICAL TESTS. BEHAVIOR ASSESSMENT-
MEASUREMENT*
BEHAVIOR THERAPY
SEE PSYCHOTHERAPY. BEHAVIOR MODIFICATION
BEHAVIORAL GENETICS
SEE PSYCHOGENETICS-BEHAVIORAL GENETICS
BEHAVIORAL MEDICINE
SEE ALSO HEALTH CARE SERVICES. PATIENT CARE
PERSONNEL AHITUOES
SEE ALSO HEALTH CARE SERVICES, PATIENT-PROFESSIONAL
RELATIONS
SEE ALSO PSYCHOLOGY, ATTITUDE TO HEALTH AND HEALTH
PROBLEMS
SEE ALSO PSYCHOPHYSIOLOGIC DISORDERS
POIHL-10539-12 0023 Pathophysiology of circulation -
The relaxation response and therapy of disease states
(human)
POIHL 10539-12 0031 Pathophysiology of circulation -
Post myocardial infarction care -Psychological aspects
(human)
POIHL-10539-12 0066 Pathophysiology of circulation -
Usefulness of relaxation response in industrial settings
P50HL-I4236-05 0013 Prevention of premature
arteriosclerosis - Patient compliance
P60HL-15158-07 0009 Comprehensive sickle cell center -
Counseling and social services
P60HL-15160-07 0003 Center for sickle cell disease -
Genetic counseling in hemoglobinopathies-Dimensions,
effectiveness
PG0HL-15162-07 0011 Comprehensive sickle cell center -
Core program- Genetic counseling and diagnostic screening
P60HL-15999-05 0004 Miami comprehensive sickle cell
center - Education, screening and counseling
R25HL-I7056-01 Improving patient compliance through
nursing action
P60HL-17269-04 0047 National heart and blood vessel
research and demonstration center - Evaluation of
competency-based educational model
ROlHL-17465-04 Beta-thalassemia screening and genetic
counseling
ROIHL-1 7958-04 Circulatory effects of operant
cardiovascular control (baboons)
R25HL-18414-03 Hypertension -Family strategies for
patient adherence
R25HL-184I8-03 Role of a supporting partner in
adherence (human)
il
R7SHI 18474 03 Blood prtssuce aducilion in an induilrml
setlinij (human)
ROIMI l»HUU:i Bchaviuidl Inctic] lor clinical cardiac
cunliol (human)
KOI HI 1 8823 02 Physiolo|!ical coirolalos of conditioned
t)laod pressure (human)
*• ROIHI l«')(i;03 Objective ov.iluation esily .iflci Ml and
heart suicery (human)
*■ ROIHl 19343 03 Behavioral influences on cardiac
contractility (monkeys)
ROIHl 19568 03 Hypertension Analysis of dru| and
behavioral therapies (human)
ROIHL 19844 02 Behavioral control ot essential
hypeilpiision (human)
ROIHl 701/9 02 Epidemiology of sudden cardiac death
among women
ROIHl 2091002 The alternative diet for coronary disease
prevention (human)
ROIHL 21318 02 Mechanisms of emotions' asthma
triggering effect (human)
ROIHL 21323 02 Raynaud's disease and temperature self
regulation (human)
ROIHL 21426 02 Learned heart rate control (human)
ROIHL 21427 02 Behavioral changes in post infarction
patients
ROlHL-21532 02 Cardiovascular homeostasis and learning
(frogs, rats, human)
** R18HL 2190601 Stanford five city multifactoi risk
reduction study
ROIHL 2206501 Intractability, medication, and coping
styles in asthma (human)
M R23HL 22345-02 Behavioral cardiovascular compliance
strategies
R23HL 22345 02 0001 Behavioral cardiovascular
compliance strategies Long term modification of dietary
patterns (human)
R23HL-22345 02 0002 Behavioral cardiovascular
compliance strategies Compliance with antihypertensive
medication regimens (human)
** ROIHL 2237801 Psyco somatic predictors of CHD in
adolescence (human)
** ROIHL 22514 01 Behavior patterns, stress, and
catecholamines
** ROlHL-22547 01 Behavioral treatment of Raynaud's
disease (human)
** ROIHL 22740 01 Behavior and cardiovascular disease -
Basic mechanisms (human)
** R01HL22809 01 Coronary prone behavior and
cardiovascular reactivity (human)
ROIHL 22847 01 Test for adherence to diets rich in
linoleic acid
** R18HL-22934-01 Behavorial approaches to adolescent
hypertension
N01HR-72973-0I Health education and attitudes of family
toward asthmatic children
NOIHR-72974 01 Self management systems for asthmatic
children
BEHAVIORAL SCIENCES (DEVELOPMENTAL)
STUDY SECTION
** ROIHL 18589 03 Psychosocial factors and outcome in
coronary disease (human)
** R01HL-20655 02 Autonomic predictors of hypertension in
children
** R0IHL-2202I-01 Asthma in families- Behavior analysis of
family interaction pattern
** R01HL-22065-0I Intractability, medication, and coping
styles in asthma (human)
BENADRYL
SEE PHENYULKOXYALKYUMINES, DIPHENHYDRAMINE
BENCE-JONES PROTEINS
SEE GLOBULINS. MYELOMA GLOBULINS, BENCE-JONES
PROTEINS
BENZANTHRACENES
SEE CYCLICS. CARBOPOLYCYCLICS. BENZANTHRACENES
BENZ(E)AZUIENES, ACONITINE TYPE
SEE ALKALOIDS, ACONINE TYPE
BENZEDRINE
SEE PHENYLALKYUMINES. AMPHETAMINE
BENZENE
R23HL 19573-01 Studies on pulmonary serotonin (mice)
BENZOATES
SEE PHENYLCARBOXYLATES, BENZOATES
1,3-BENZODIOXOLES
ROIHL 20622-02 Pulmonary uptake and accumulation of
drugs (rabbits, rats)
BENZOFURANONES, PHTHALIDES,
BROMSULPHTHALEIN
POIHL 08899-14 0061 Tolerance to respiratory gases in
health and disease Hepatic oxygenation and secretory
functions (rats, dogs)
BENZOIC ACID, BENZOATES
SEE PHENYLCARBOXYUTES. BENZOATES
•Excludes routine methodology OR covers only general proiects which preclude indexing at the specific level
•"Oriented significantly to above subject
M Grant has subproiects describing spec!
See Appendix for investigator's name and
BEN
BENZOPYRANS, XANTHENES. FLUORESCEINS
KOIHl 1//U2U4 lleilio optical dytt ai piobat ol hiarl
eicilabilily
BENZOPYRENES
,11 (.YClli;', CAHBOPOircrCllCS. B£N/OPYR£NtS
BENZO(B)PYRIDINE
Ml OIIINOIINI',
BENZO(C)PYRIDINE
Ml OIIINOIINI', I'.OODINOLINtS
BENZO-ALPHA-PYRONES
ROIHl 09163 ri Control mechanisms in hemoslaiil
(human)
" POIHL 11414 II 0033 Thrombosis and atheroicleiosis
program Human coumaiin induced prothrombin
ROIHL 14847 07 Mechanism of action of vitamin K and
anticoagulants (rats)
ROIHL 15698 12 factors affecting the action of
anticoagulants (rats, human)
POIHL 185/6 03 0003 Thrombosis research program
project Biocompatible materials
ROIHL 21476 02 Anticoagulant drug absorption
interactions (rats)
BENZO-ALPHA-PYRONES,
BISHYDROXYCOUMARIN
POI HL 13738 08 0003 Cardiac assist devices and
artificial hearts Pathophysiological effects of the artificial
heart (calves)
ROIHL 15698 12 Factors affecting the action of
anticoagulants (lats, human)
R01HL-2I47602 Anticoagulant drug absorption
interactions (rats)
BENZO-ALPHA-PYRONES, WARFARIN
ROIHL 13754 08 Postoperative thromboembolism in
surgical patients (human)
R01HL-15698-I2 Factors affecting the action of
anticoagulants (rats, human)
POIHL 18576 03 0007 Thrombosis research program
project Relationships between coagulability and
thrombosis (human, animals)
ROIHL 18738-02 Prevention of postoperative venous
thrombi (human, cattle)
** ROIHL 1977202 Role of warfarin metabolism in
antivitamin K activity (rats)
BENZOPYRROLE CARBOXYLIC ACIDS,
INDOMETHACIN
POlHL-06835 17 0031 Cardiovascular disease Synthesis
of potent antagonist of pressor action of angiotensin II
(animals)
P01HL-I1351 12 0015 Cellular and molecular
mechanisms of myocardial function - Eftects of hypoxia
and ischemia on ion exchange and heart function (rabbits)
ROIHL 11802-10 Cardiovascular surgical research (dogs.
sheep, swine, cats, monkeys)
P50HL-14192-08 0003 Specialized center of research in
hypertension - Prostaglandins as mediators of renin
secretion (human, dog)
P50HL I42I4 07 0026 Newborn lung center for hyaline
membrane disease - Hemodynamic studies of HMD-
Prostaglandins production and blockers (lambs)
P01HL-I4388 07 0180 Regulation of the circulation in
pathological states - Regulation of cerebral blood flow
(dogs, monkeys)
POIHL 14388 07 0225 Regulation of the circulation in
pathological states - Release of renal prostaglandins by
saluretic-diuretic agents (dogs)
** P01HL-I4388-07 0230 Regulation of the circulation in
pathological states Effects of indomethacin in patients
with carcinoid syndrome
POIHL 14388-07 0231 Regulation of the circulation in
pathological states • Mechansim of cutaneous
vasodilatation in Pagefs disease of bone
ROIHL-15580-06 Humoral control of pulmonary and
systemic circulation (animals)
ROlHL-15681-06 Coronary flow studies of partially
obstructed vessels (dogs)
ROIHL 16437-05 Drug treatment of atherosclerosis
(rabbits, monkeys)
ROlHL-16489-04 Renal prostaglandins -Synthesis and
function (human, dogs, rats)
R0IHL-I6496-04 Prostaglandins and renin experimental
hypertension (rabbits)
ROlHL-16760-05 Dynamic control of coronary blood flow
(dogs)
R01HL-I758I-03 Patent ductus arteriosus and pulmonary
hypertension (dogs)
ROIHL 17759-03 Studies of myocardial reactive hyperemia
(dogs, human)
ROIHL 18579-03 Vasoactive hormones and blood pressure
regulation (dogs, rats, rabbits)
ROIHL I87I804 Prostaglandin precursors and vascular
reactivity (dogs)
POIHL-18827-02 0006 Platelet vessel wall interactions in
thrombogenesis Platelet immune injury in man
ROlHL-18845-04 Regulation of renal circulation and salt
excretion (rats, dogs)
ROIHL 18932-03 Brain microcirculation observed in vivo
after trauma (mice)
(contd)
tic research aspects,
grant number.
BEN
ROlHL-18979-02 Mechanisms in local regulation of
coronary flow (rabbits)
R01HL19202-03 Adenosine, prostaglandins in relation to
coronary flow (guinea pigs)
ROlHL-19218-03 Local regulation of coronary flow by
prostaglandins (rabbits)
ROlHL-19287-03 The antihypertensive function of the
renal medulla (human, rats, rabbits)
ROlHL-20783-02 Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
ROlHL-22087-02 Humoral mediators of pulmonary
inflammation (guinea pigs)
R23HL-2230901 Cardiovascular pharmacodynamics in
immature dogs
R23HL-22438-01 The etiology of genetic hypertension
(rats)
R01HL-22527-0I Prostacyclin-thromboxanes in the
cardiovascular system (human rabbits)
ROlHL-2256302 Prostaglandins, the kidney and
hypertension (rats)
ROlHL-2257301 Treatment of post surgical
vasoconstriction (dogs, monkeys, human, rats)
ROlHL-22783 01 Hemodynamic induction of intimal
fibromuscular lesion
ROIHL 22836-01 The spontaneously hypertensive kidney
(rats)
R23HL-22882-01 li/lodulation by disease of effect of
furosemide in man
ROlHL-23602-01 Physiology of renin, aldosterone and
prostaglandin (human, rats, dogs)
BENZOPYRROLES, INDOCYANINE GREEN
" ROlHL-03181-21 0029 Hemodynamics as applied to
surgical problems - Indocyanine green clearance for
estimation of hepatic blood flow (human)
BENZOPYRROLES, INDOLEAMtNES (GENERAL)
SEE ALSO BENZOPYRROLES, SEROTONIN
ROIHL 13315-08 Disposition of vasoactive hormones in
mammalian lung (rats, rabbits, human)
BENZOPYRROLES, INDOLES (SEE ALSO
APPROPRIATE SPECIFICS UNDER
BENZOPYRROLES)
SEE ALSO ALKALOIDS. VINBUSTINE
SEE ALSO ALKALOIDS, VINCA
ROlHL-1364511 Tryptophan-induced pulmonary
emphysema (cattle, goats, rabbits)
R01HL-16471-D5 Cardioactive alloyohimbines and related
Indole alkaloids
ROlHL-21540-02 Specific inhibitors of coagulation and
fibrinolysis (rats, rabbits, dogs)
BENZOPYRROLES, METHOXYINDOLES
ROlHL-13645-11 Tryptophan-induced pulmonary
emphysema (cattle, goats, rabbits)
BENZOPYRROLES, PHYSOSTIGMINE
ROlHL-14844-06 Mucous glycoprotein in human respiratory
epithelium (also wheat)
BENZOPYRROLES, SEROTONIN
ROlHL-05883-18 0001 Reflex control of resistance and
capacitance vessels - Naturally occurring vasoactive
substances and the vascular neuroeffectors (dog)
ROlHL-09283-14 Pharmacology of molluscan hearts (also
rabbits)
POlHL-10342-13 0019 The integrated function of
respiration and circulation Cerebral circulation and
metabolism (dogs)
ROIHLI 1897-11 Pathogenesis of experimental
atherosclerosis (rabbits, guinea pigs)
ROlHL-13315-08 Disposition of vasoactive hormones in
mammalian lung (rats, rabbits, human)
ROlHL-13323-08 Intrarenal pressure and renal function
(human, dogs)
ROlHL-13466-08 Pulmonary platelets in shock, trauma
and embolization (dogs, pigs, rats)
P50HL-14147-08 0018 Specialized center of research in
thrombosis - Biochemical aspects of platelet function in
thrombosis and cell growth (human)
P50HL-14164-07 0044 A/S SCOR-Comparative and
experimental atherosclerosis - Cell biology-atherosclerosis
project (pigeons)
P50HL-I4217-08 0057 Specialized center of research in
thrombosis - Pharmacology -Platelet biochemistry (human,
animal)
Regulation of the circulation in
• Ionic basis of depolarization (rats.
POIHL 14388-07 0168
pathological states
tissue culture)
POIHL 14388-07 0178
pathological states
Regulation of the circulation in
- Structural and functional
consequences of denervation (rats)
POlHL-14388-07 0179 Regulation of the circulation In
pathological states - Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
POlHL-14580-07 0001 Program project in respiratory
mechanics - Micromechanics of the lung (dogs, rats)
ROlHL-15013-07 Lung oxidative metabolism and energy
production (rodents, rabbits)
ROlHL-16714-05 Endothelial cell communication in
homeostasis (human, mammals)
ROlHL-l 7370-03 Synaptic chemistry and cardioregulation
in Limulus
22
P50HL 17667-04 0031 Study of ischemic heart disease •
Pathophysiology in ischemic heart disease (dog. cat. rabbit
monkey)
ROlHL-l 771 1-05 Mechanism of hypoxic regulation of lung
circulation (rats, cats, guinea pigs)
ROlHL-l 7768-04 Development of collateral ventilation
(dogs, fish, horses)
POIHL 17812-04 0005 Thrombosis and plasma proteins -
In vitro systems of normal platelets, white cells, sera
(human)
POlHL-1 7812-04 0007 Thrombosis and plasma proteins -
Blood components -Response to endotoxin (dogs, baboons)
ROlHL-1807004 Regulation of intrapulmonary airways
and vessels (human animals)
ROlHL-1819104 Models of hypoxic pulmonary
hypertension (cattle, minipigs)
ROlHL-18502-03 Enzymatic regulation of platelet function
(human)
POIHL 18576-03 0001 Thrombosis research program
project - Platelet da nage from physical forces and
artificial surfaces (human)
ROIHL 18584-03 Effects of physical forces on platelets
(human)
P50HL-18828-03 0004 Specialized center of research in
thrombosis - Membiane changes in platelet physiology-Role
of complement (mite, human)
ROIHL 18936-02 heart preservation and transplantation
studies (rat)
Experimental neurogenic
Monoamines and hypertension
POlHL-18974-03 0008
hypertension program
(rats)
POlHL-18974-03 0011
hypertension program
Experimental neurogenic
. „ Biochemistry and regulation of
brain tryptophane hydroxylase (rats)
P50HL19153-02 0002 SCOR -Pulmonary edemas -Eitology.
pathogenesis - Lunp fluid dynamics -Classical mediators
and their inhibitors (sheep)
POIHL 19242-02 000/ Study of vascular smooth muscle
NE release in and reactivity of vascular smooth muscle
(animals)
R23HL-1957301 Studies on pulmonary serotonin (mice)
POlHL-19717-02 000. Response of the lung to mjury -
Cellular level studies of prostaglandin-like molecules
(cattle)
ROlHL-201 14-02 Collagen-platelet interaction and human
aorta collagen (human)
ROlHL-20411-03 Platelet fatty acid metabolism in
diabetes (rat, rabbit, guinea pig)
R01HL-21I15-01 Prevention of 02 toxicity with superoxide
dismutase (rats)
R23HL 21116-02 Mechanisms of membrane and tissue
damage in lung (dogs, rabbits)
ROlHL-21217-01
platelets
Ion and 5-hydroxytryptamine transport by
Perinatal control of the ductus arteriosus
R23HL-2140902
(sheep)
ROlHL-22040-01 Regulation of lysyl-cross-linking in
vascular tissue (rats, turkeys)
ROlHL-2207701 Vasoactive amine disposition In cultured
endothelium (rabbits)
ROlHL-22177-02 Mechanisms of control of pulmonary
smooth muscle (dogs)
ROlHL-22223-01 The cardiopulmonary junction (dogs,
models)
ROlHL-22244-01 Cardiopulmonary bypass and the
vascular endothelium (dogs)
ROIHL 22555-01 Structure and function of platelet
activating factor (rabbits, human)
R01HL-2256I-01 Hormonal control of mesenteric
circulation (cats)
ROlHL-22573-01 Treatment of post surgical
vasoconstriction (dogs, monkeys human rats)
POlHL-22619-01 0008 Cellular mechanisms of heart
failure - Molecular mechanisms and differential contractile
responsiveness In VSM (dogs)
ROlHL-23614-02 Pharmacology of relaxation in smooth
muscle (mollusks)
BENZOPYRROLES, SEROTONIN INHIBITORS
SEE ALSO ALKALOIDS. ERGOT. METHYSERGIDE
SEE ALSO CYCLIC AMINO ACIDS, PHENYULANINE P-
CHLOROPHENYLALANINE
SEE ALSO CYCLOHEPTANES. CYPROHEPTADINE
" P50HL-19I53-02 0002 SCOR -Pulmonary edemas -Eitology.
pathogenesis - Lung fluid dynamics-Classical mediators
and their inhibitors (sheep)
ROlHL-22520-01 Pulmonary vascular response to group 8
Streptococci (human, mammals)
ROlHL-22573-01 Treatment of post surgical
vasoconstriction (dogs, monkeys, human, rats)
BENZOQUINONES
SEE QUINONES
BENZYLPENICILLINIC ACID
SEE ANTIBIOTIC:;. PENICILLIN G
BERBERINE
SEE ALKALOIDS BERBINES
BERBINES
SEE ALKALOIDS BERBINES
•Excludes toutinc methodology OR covers only general projects which preclude indexing at the specific level
Oriented significanlly to above sub|ecl.
M Grant has subproiects describing specific research aspects.
See Appendix for investigators name and grant number
BIL
BERYLLIOSIS
SEE METALS POISONING, BERYLLIOSIS
BERYLLIUM (COMPOUNDS)
SEE METALS, ALKALINE EARTH METALS. BERYLLIUM
BETA GLOBULIN(S)
SEE GLOBULINS, BETA GLOBULINS
BETA RECEPTORS
SEE NEUROTRANSMinERS RECEPTORS ADRENERGIC
RECEPTORS, BETA RECEPTORS
BETATRON
SEE RADIATION, PARTICLE ACCELERATORS
BETHANIDINE
SEE GUANIDINES. BETHANIDINE
BIBLIOGRAPHY
SEE PUBLICATIONS. LITERATURE SURVEY
BICARBONATES
SEE CARBONATES. BICARBONATES
BICUSPID VALVE
SEE HEART. VALVES, MITRAL VALVE
BIG BIG GASTRIN
SEE GASTROINTESTINAL HORMONES. GASTRIN
BIG GASTRIN
SEE GASTROINTESTINAL HORMONES. GASTRIN
BILE
ROlHL-09744-14 Experimental vascular sclerosis
(monkeys, rabbits)
** ROlHL-15698-12 Factors affecting the action of
anticoagulants (rats, human)
ROIHL 22567-01 Validation of a cholesterol absorption
method in man
BILE, CHOLAGOGUES AND CHOLERETICS
SEE ALSO BILE ACIDS AND SALTS
SEE ALSO BILE ALCOHOLS
SEE ALSO GASTROINTESTINAL HORMONES, PANCREOZYMIN-
CHOLECYSTOKININ
SEE ALSO GASTROINTESTINAL HORMONES. SECRETIN
♦* ROlHL-22748-01 Effect of bile sequestration on VLDL
metabolism (human)
BILE ACIDS AND SALTS
SEE ALSO BILE. CHOLAGOGUES AND CHOLERETICS
ROlHL-02033-23 Regulation of cholesterol esters in blood
and tissues (rat. cattle, human)
ROlHL-03299-21 Dietary effects on cholesterol metabolism
(rats, rabbits)
R01HL-06222-18 Chnical and laboratory studies In lipid
metabolism (human, mammals, non-human)
** ROlHL-0787816 Metabolism of neutral sterols (rats,
rabbits)
P01HL-08214-15 0041 Chemical and biological properties
of lipids - Physico-chemical regulation of enzymes in lipid
metabolism
POlHL-08899-14 0061 Tolerance to respiratory gases in
health and disease - Hepatic oxygenation and secretory
functions (rats, dogs)
P01HL08974-14 0024 Natural and experimental
atherosclerosis - Atherosclerosis, sterol and lipoprotein
metabolism in nonhuman primates
** ROlHL-09610-14 Control of cholesterol metabolism-Bile
acid transport
R01HL-I0894-12 Intestinal bacteria and steroid
metabolism (human, guinea pigs rabbits rats)
" ROlHL-l 1901-12 0004 Effects of metabolic surgery on
the hyperlipidemias ■ Ileal bypass -Cholesterol dynamics
studies (rats, rabbits, dogs)
" ROIHL 11901-12 0013 Effects of metabolic surgery on
the hyperlipidemias - Human cholesterol and bile acids
dynamics -ileal bypass
ROIHL-1 1901-12 0015 Effects of metabolic surgery on
the hyperlipidemias - Portacaval shunt for cholesterol
reduction (dogs, rabbits)
" ROIHL 11901-12 0019 Effects of metabolic surgery on
the hyperlipidemias - Cholesterol, bileacids. lipoproteins in
obese humans
R01HL-I1901-12 0020 Effects of metabolic surgery on
the hyperlipidemias - Je|uno-ileal bypass -Endogenous
animal model of obesity (rats)
ROlHL-16364-04 Regulation of lipid biosynthesis and
transport (rats, swine. Xenopus)
ROlHL-16796-05 Cholesterol regulation by HMG-CoA
reductase (rats, human)
ROlHL-17332-04 Use of the gut for therapy of coronary
artery disease (mammals)
ROlHL-17564-03 Unsaturated fats-Mode of
hypocholesterolemic action (minipig)
R01HL-I7818-05 Metabolism of cholesterol and cholesterol
in man (also rats, monkeys)
R01HL-I8219-04 Regulation of cholesterol metabolism
(rats)
P50HL-I9362-02 0009 A7S SCOR -Atherosclerosis in
nonhuman primates - Cholesterol metabolism and
intestinal microflora (baboon)
ROlHL-20483-03 Sterol balance and cholesterol absorption
in diabetics (human)
(contd)
Bll
raiHl 77633 01 0007 Collulir and molnculai biology al
lipoprolain mttabolism Sterol metabolism m tissue
ciiltuie crIU
KlMHL ?.t^98 01 Dietary tat rholestrrol and bile icid
luinover (i.it\)
BILE ACIDS AND SALTS, ENTEROHEPATIC
CIRCULATION
ROIHl 10894 I? Intestinal bacteria and steroid
metabolism (human. (Uinea pigs, rabbits, rats)
BILE ALCOHOLS
SEE ALSO BIIE. CHOUGOGUES AND CHOIEREIICS
ROIHl 10894 I? Intestinal bacteria and steroid
metabolism (human, guinea pigs, rabbits, rats)
ROIHL 17818 05 Metabolism ol cholesterol and cholesterol
in man (also rats, monkeys)
BILE (DUCT) OBSTRUCTION
SEE BILIARY TRAC1 DISORDERS. BILE OBSTRUCTION
BILE PIGMENTS
SEE ALSO JAUNDICE
ROIHL 7148301 Electronic, thermodynamic and kinetics
ol hemoglobin
BILE PIGMENTS, BILIRUBIN
ROIHL'77752'01 Synthesis of labeled hemes (or protein
NMR studies
BILHARZIASIS
SEE PARASITIC DISEASES. HELMINTH INFECTIONS.
SCHISTOSOMIASIS
BIUARY ATRESIA
SEE BILIARY TRACT DISORDERS. BILIARY ATRESIA
BILIARY CALCULI
SEE BILIARY TRACT DISORDERS. CHOLELITHS
BILIARY TRACT DISORDERS, BILE OBSTRUCTION
SEE ALSO BILIARY TRACT DISORDERS. BILIARY ATRESIA
SEE ALSO BILIARY TRACT DISORDERS. CHOLELITHS
R01HL02965-22 Metabolism of plasma lipoproteins (rats,
chickens, human)
ROlHL-0622117 Composition and structure of plasma
lipoproteins (human, turkeys, baboons]
P50HL-1423707 0004 Support for arteriosclerosis center
- Synthesis, secretion of normal, abnormal plasma
lipoproteins (rodents, monkeys)
ROlHL-23945-06 Pathologic effects on cells of modified
lipoproteins (rats, human)
BILIARY TRACT DISORDERS, BILIARY ATRESIA
R01HL06221-17 Composition and structure of plasma
lipoproteins (human, turkeys, baboons)
BIUARY TRACT DISORDERS, CHOLELITHS
POlHL-0683517 0016 Cardiovascular disease ■ Metabolic
interactions to polyunsaturated fatty acids in atherogenic
diet (dogs)
R01HL09744-I4 Experimental vascular sclerosis
(monkeys, rabbits)
R01HL10894-12 Intestinal bacteria and steroid
metabolism (human, guinea pigs, rabbits, rats)
R01HL11901-12 0013 Effects of metabolic surgery on
the hyperlipidemias - Human cholesterol and bile acids
dynamics-ileal bypass
•* P60HL1516905 0012 Support for center for sickle cell
disease - Evaluation of the incidence of cholelithiasis in
sickle cell disease (human)
** ROlHL-1781805 Metabolism of cholesterol and cholesterol
in man (also rats, monkeys)
** R01HL-18623I2 Physical chemistry of biologically active
lipids (bacteria, plant, cattle, human)
NOlHV-22913-09 Lipid research clinic
NOlHV-62900-00 Study of breast cancer and reserpine use
(human)
BILIARY TRACT DISORDERS, GALLBLADDER
DISORDERS
SEE ALSO BILIARY TRACT DISORDERS. CHOLELITHS
ROlHL-19839-09 Factors in youth predisposing to chronic
diseases (former college students)
BILIARY TRACT DISORDERS CHEMOTHERAPY
SEE ALSO BILIARY TRACT PHARMACOLOGY
SEE ALSO LIVER DISORDERS CHEMOTHERAPY
ROlHL-1089412 Intestinal bacteria and steroid
metabolism (human, guinea pigs, rabbits, rats)
BILIARY TRACT DISORDERS DIAGNOSIS (INCL
EXAMS)*
SEE ALSO LIVER DISORDERS DIAGNOSIS (INCL EXAMS)*
R01HL06221-17 Composition and structure of plasma
lipoproteins (human, turkeys, baboons)
P60HL-15169-05 0012 Support for center for sickle cell
disease - Evaluation of the incidence of cholelithiasis in
sickle cell disease (human)
BILIARY TRACT EXAMINATIONS
SEE BILIARY TRACT DISORDERS DIAGNOSIS (INCL E)(AMS)*
BILIARY TRACT OBSTRUCTION
SEE BILIARY TRACT DISORDERS. BILE OBSTRUCTION
23
BILIARY TRACT PHARMACOLOGY
Sff ALSO BILIARY IRACI UISORDIHS CHEMOTHERAPY
SEE ALSOIIVIR I'llARMACOlOGY
" ROIHl 72/48 01 llteil ol bile sequestration on VtOt
mptabolism (human)
BILIRUBIN
SEE BILE PIGMENTS BIIIRDBIN
BINDING (CHEMICAL)
SEE CHEMICAI BONDS BINDING
BINDING PROTEINS
SEE PROtEIN BINDING
BINDING REAGENTS
SEE METAL COMPLEXES. LIGANDS
BIOANALYTICAL AND METALLOBIOCHEMISTRY
STUDY SECTION
•• ROIHL 13651 07
compounds
•* R01HL2225201
NMR studies
ROIHL 2238701
ROIHL 2282101
myoglobinemia
ROIHL 23120 01
X ray pholoelectron spectroscopy of heme
Synthesis ol labeled hemes for protein
Metalloen;ymes and disease
A routine screening analysis for
Chelating agents as blood substitutes
BIOASSAY*
SEE ALSO CHEMICAL STRUCTURE BIOLOGICAL ACTIVITY
SEE ALSO IMMUNOLOGICAL TESTS AND IMMUNOASSAY,
IMMUNOASSAY*
NOIHB 8292400 Source of human urinary erythropoietin
NOlHB-8292600 Source of human urinary erythropoietin
POlHL-06312 17 0052 Surgical cardiology • Assay of
metabolic variables of rat heart
ROIHL 11172-12 Physiology and biochemistry of
fibrinolytic enzymes (human, animals)
POIHL 11310-12 0096 Mechanisms of cardiovascular
disease Complement chemistry and biology (human,
rabbits)
P50HL14164-07 0040 A/S SCOR-Comparative and
experimental atherosclerosis - Core angiochemistry
laboratory
ROlHL-1489007 Platelet prostaglandms (human, rabbits)
ROlHL-16346-09 Enzyme assay for blood clotting (human)
R01HL1793003 Platelet membrane function -Assessment
and application (animals)
ROlHL-18908-03 Angiotensin converting enzyme of human
serum
P50HL1915702 0001 Studies in cystic fibrosis and
bronchiolitis - Laboratory core unit
*• P50HL-19157-02 0004 Studies in cystic fibrosis and
bronchiolitis - Macromolecular regulators of mucus
secretion-Invertebrate model
** P50HL-19157-02 0007 Studies in cystic fibrosis and
bronchiolitis - Analysis of cystic fibrosis factors (human)
** ROlHL-19272-03 Studies on the Passovoy factor (human)
** ROlHL-19331-03 Hirudin Isolation and utilization (leeches)
R23HL-2 1208-02 Structure-function relationships of human
factor VIII
R01HL-23312-0I Hemodynamics and vasoactivity In renal
hypertension (human, dogs)
BIOAUTOFUEL CELL
SEE BIOMEDICAL ENGINEERING, BIOLOGICAL POWER
SYSTEMS
BIOAVAILABILITY OF DRUGS
SEE DRUGS, PHARMACOLOGY, BIOAVAILABILfTY /
BIOCHEMICAL EVOLUTION
SEE BIOLOGY, SYSTEMATIC, EVOLUTION BIOCHEMICAL
BIOCHEMICAL INFORMATION SYSTEMS
SEE CHEMICAL AND DRUG INFORMATION SYSTEMS
BIOCHEMICAL PHARMACOLOGY
SEE DRUGS, PHARMACOLOGY. BIOCHEMICAL
BIOCHEMISTRY (GENERAL)*
SEE ALSO MICROBIAL CHEMISTRY STUDY SECTION
SEE ALSO MOLECUUR BIOLOGY
SEE ALSO PHYSICAL PROPERTIES. RHEOLOGY (NOT INCL.
BLOOD)
SEE ALSO PHYSIOLOGICAL CHEMISTRY STUDY SECTION
ROIHL-02942-22 Biochemistrv of cardiovascular connective
tissue (human, cattle, primates)
** PG1HL-06285-18 0178 Cardiovascular-respiratory
physiology and biochemistry - Biochemical regulation of
hypertrophy (rats, rabbits)
** P01HL-12373-10 0018 Cardiopulmonary physiology and
pathophysiology - Biochemistry laboratory
** POlHL-1373707 0031 Assisted circulation - Myocardial
ischemia -Biochemical changes (dogs)
ROIHL-1919503 Hormonal regulation of lung function
(rats)
POlHL-19717-02 0001 Response of the lung to injury -
Lung elastic tissue (animals)
M ROlHL-20079-02 Thromboresistant material
POlHL-2055202 9001 The development and regression of
cardiac hypertrophy - Core A -Pathology
Ammo acid analyzer for biochemical
Bioenergetics apparatus in heart
klO
POIHl 705111 01 0004 Vatculir nturotttfcloi
mtchanitms in heilth and dl^eau Neurotllector
ch«(icl«ristici of moenleiic and pulmonary blood vtiwll
(rabbits)
•• POIHI 20SKI 01 9007 Vaiculai neuioelleclof
mechanisms in health and diseiM Biochemiilry con
POIHI 70S94 07 9001 Dynamics ol neutrophil (lattaM in
the lunc BiochirmiMry and immunology core
•• ROIHl 724/1 01 Biochf mislry ol prothrombin quick
(human)
BIOCHEMISTRY, CLINICAL
Sir CHEMISIRY. ClINICAl
BIOCHEMISTRY STUDY SECTION
SEE ALSO PATHOBIOLOGICAl CHEMISTRY STUDY SECTION
** ROIHL 07558 7? Structure function relationships in the
heme proteins (human, cattle)
** ROIHL 08299 16 Molecular biology of hemeryfhiin and
hemocyanin (invertebrates)
•* ROIHL 09364 14 Ion transport by heart mitochondria
(cattle, rat. rabbit)
** R01HL1111917
research
** ROIHL 12576 10
mitochondria
*• ROIHL 12585 10 Structural properties of ma late
dehydrogenase (swine)
** ROIHL 1303508 Heart mitochondrial malate
dehydrogenase regulation
** ROIHL 1361909 Microsomal electron transport in liver
and heart (human, mammals)
** ROIHL 14483-08 Energy conservation in heart
mitochondria (cattle, E coli, human)
** ROlHL-1500207 Biochemical pharmacology of guanylate
cyclase in lung (cattle, rats)
** ROIHL 1501307 Lung oxidative metabolism and energy
production (rodents, rabbits)
** ROIHL 15104-07 A mechanism for oxidative
phosphorylation
** ROlHL-15476-05 Mechanism and control of sterol
biosynthesis (rats)
** ROIHL 15535-06 Structure and function of human plasmin
** ROlHL-1589205 Inhibitors of proteinases (human, cattle,
swine)
** ROlHL-16549-04 Cardiotonic steroid NaK ATPase
interactions (cattle)
** R01HL16647 05 Studies on the control of sickle cell crisis
(human)
** ROlHL-16686-04
bacteria)
** ROlHL-1737203 Adenine nucleotide maintenance in the
ischemic heart (rats)
** R01HL1796304 Human erythrocyte carbonic anhydrase
** ROlHL-1803803 Structure and function of heart
mitochondria (cattle)
** ROIHL'18095'04 Human dopamine-betahydroxylase (also
cattle)
** ROIHL-18179-03 Heart, platelet, and muscle myosins and
actomyosins (cattle)
** ROlHL-18554-03 Taurine metabolism in mammalian heart
(rodents, cattle, swine)
** R01HLI8567-03 A routine diagnostic test for minimal
heart damage (human, rat)
** ROlHL-18593-03 Characterization of heart valve collagen
(human, pig)
** R01HL18682-03 Protein kinase and cholesterol
metabolism in aorta (rabbits)
** ROlHL-19181-02 Regulation of heart cAMP-dependent
protein kinase (rodents)
** ROIHL 19532-01 Oxygen toxicity In the red cell (human)
** R01HL-19654-03 Biochemical-pharmacological evaluation
of lung cells (rabbits)
** ROlHL-2011601 Heart lactate dehydrogenase -The complex
with NADH (pig)
** ROlHL-20544-02 Integrated regulation of myocardial
energy metabolism (rats, guinea pigs)
•* ROlHL-20658-01 Myocardial energy transport -Creative
kinase (human, cattle, dog)
** ROlHL-2090902 Clofibrate-enhanced lipid oxidation by
peroxisomes (rats)
** R23HL-2142101 Myocardial and vascular contractility and
cyclic nucleotides (cattle, rats)
" ROlHL-2226502 Isozymes of heart glutamate aspartate
transaminase (swine, ducks)
** ROlHL-2229001 Cardiac energy metabolism and protein
synthesis (mice)
** R23HL-22383-01 Biosynthesis -Response to oxygen
depletion (human, primates, rats)
** ROlHL-22486-01
cells (swine)
** ROlHL-22538-01
Properties of cytochrome oxidase (cattle.
•Excludes routine methodology OR covers only general proiecls which preclude indexing at the specific level,
"Oriented significantly to above subject.
Enzyme regulation in cultured arterial
Myosin as a multi-enzyme complex (dogs.
rabbits)
** ROlHL-22896-01 Immediate metabolic fates of kinins and
angiotensins (rat, rabbit, guinea pig)
** R23HL-22984-01 Cyclic AMP dependent protein kinases in
hypertension (rat)
BIOCYBERNETICS
SEE INFORMATION PROCESSING AND CONTROL (BIOLOGICAL)
BIOCYBERNETICS (NEURAL)
SEE INFORMATION PROCESSING AND CONTROL (NEURAL)
(contd)
M Grant has subprojects describing specific research aspects
See Appendix for investigator's name and grant number
BIO
BIODEGRADATION, BIOTRANSFORMATION
(METABOLISM)
SEE METABOLISM, BIOTRANSFORMATION
BIOELECTRICITY
SEE ELECTROPHYSIOLOGY
BIOENERGETICS
SEE ALSO BIOLOGICAL TRANSPORT
SEE ALSO MUSCLE METABOLISM
SEE ALSO OXIDATION-REDUCTION
SEE ALSO OXIDATIVE PHOSPHORYLATION
SEE ALSO PHOTOBIOLOGY
SEE ALSO PHOTOCHEMISTRY
R01HL02363-20 Kinetics of water and electrolytes in
shock (dogs, rats)
R01HL05949-18 Biochemistry of muscle contraction (rats,
rabbits)
POlHL-06285-18 0195 Cardiovascular-respiratory
physiology and biochemistry - Thyroid thermogenesis and
sodium transport (rats)
POlHL-06285-18 0211 Cardiovascular-respiratory
physiology and biochemistry ■ Purple membrane of
Halobacteria
POlHL-06664-17 0036 Cardiopulmonary function in
remediable vascular disease - In vitro studies on the
mechanism of ischemic damage to cells (rabbits)
P01HL06664-17 0040 Cardiopulmonary function in
remediable vascular disease - The coupling of ion transport
to metabolism (toads)
R01HL10018-11 Effect of aging on beating heart cells in
culture (rats)
POlHL-1 1310-12 0068 Mechanisms of cardiovascular
disease - Pharmacological intervention and myocarcial
oxygen consuption (human, dogs)
*♦ P01HL1131012 0094 Mechanisms of cardiovascular
disease - Physics of pulsatile fluid flow (dogs)
POIHLI 1310-12 9001 Mechanisms of cardiovascular
disease - Core support-hospital beds
M POlHL-l 1351-12 Cellular and molecular mechanisms of
myocardial function
POlHL-l 1351-12 0004 Cellular and molecular
mechanisms of myocardial function ■ Molecular
mechanisms of contractile function and differentiation
(animals)
** POIHLI 1351-12 0006 Cellular and molecular
mechanisms of myocardial function ■ Molecular physiology
and energetics of muscle (frogs)
** P01HL11351-12 0015 Cellular and molecular
mechanisms of myocardial function ■ Effects of hypoxia
and ischemia on ion exchange and heart function (rabbits)
** POlHL-11351-12 0019 Cellular and molecular
mechanisms of myocardial function ■ Mechano-chemical
kinetics of small perturbations
** POlHL-11351-12 0021 Cellular and molecular
mechanisms of myocardial function - Muscle energetics
(frogs)
** P01HL-1135M2 0022 Cellular and molecular
mechanisms of myocardial function - Energetic sequelae of
shortening-Myothermal and biochemical (frogs)
** P01HL11351-12 0023 Cellular and molecular
mechanisms of myocardial function ■ Energetics of
mammalian muscle (rats)
POlHL-1 1351-12 0024 Cellular and molecular
mechanisms of myocardial function - Steady state and
transient kinetics of frog myosin, SI, and ATPase
ROlHL-1 1906-11 Comparative study of heart function
(cats, rats, hedgehogs, squirrels)
POlHL-12157-11 0049 Functions and mechanisms of cell
membrane ion transport - Ouabain-insensitive cation
transport in duck red cells
ROlHL-1257610 Bioenergctics apparatus in heart
mitochondria
ROlHL-13651-07 X-ray photoelectron spectroscopy of heme
compounds
POlHL-1373707 0005 Assisted circulation - Piezoelectric
assist device (animals)
** P50HL-14138-05 0015 Center for research on
atherosclerosis - Arterial wall-Intermediary metabolism,
enzyme activity and bioenergetics
** P50HL-14217-08 0057 Specialized center of research in
thrombosis - Pharmacology--Platelet biochemistry (human,
animal)
P50HL-1421708 0058 Specialized center of research in
thrombosis • Mechanisms of induction and inhibition of
platelet reaction (human, pig)
** P50HL14217-08 0059 Specialized center of research in
thrombosis - Energy metabolism and platelet function
(human)
** R01HL1434407 Platelet function and adenine nucleotide
metabolism (human)
** P01HL14388-07 0154 Regulation of the circulation in
pathological states - Energetics of smooth muscle
contraction (rats)
POlHL-14388-07 0175
pathological states -
from cardiac muscle
** POlHL-1441407 0008 Environmental influences on
cardiorespiratory and cellular functions - Energetics of
swimming (human)
** ROlHL-14461-08 Cardiac metabolism in heart failure
(rats)
Regulation of the circulation in
Functional studies of selected proteins
24
R01HL14820-07 Factors affecting physiology of biological
membranes (human)
ROlHL-150 13-07 Lung oxidative metabolism and energy
production (rodents, rabbits)
ROlHL-1528406 Hemoglobin and myoglobin kinetic
studies (human, animals)
POlHL-1583506 Study of muscles related to heart
disease
P01HL1583506 0010 Study of muscles related to heart
disease - Muscle structure and reaction to injury (mice,
rats)
POlHL-15835-06 0011 Study of muscles related to heart
disease - Energetics and mechanism of muscle contraction
(frogs, rabbits)
POIHL 15835-06 0012 Study of muscles related to heart
disease - Contraction and energetics of visceral and
vascular smooth muscles (rabbits)
P01HL1583506 0013 Study of muscles related to heart
disease - Cardiac bioenergetics (rats)
ROlHL-16101-05 Protein-lipid interaction (bacteria,
models)
P01HL1625106 0009 Membrane-bound enzymes in heart
and other tissues NADH dehydrogenase and site I of
oxidative phosphorylation (yeast)
P60HL-17269-04 0018 National heart and blood vessel
research and demonstration center Mitochondria and
energetics (rabbits, dogs)
P60HL-17269-04 0019 National heart and blood vessel
research and demonstration center • Sarcoplasmic
reticulum (dog. rabbit, hamster, cat)
R01HL1759203 Activation and contraction heat in
enlarged hearts (rabbits)
P50HL1 766504 0029 Study of ischemic heart disease •
Myocardial protein synthesis and degradation in low oxygen
states (rabbit, dog)
P50HL17667-04 0012 Study of ischemic heart disease -
Biochemistry of normal and ischemic heart -Glycolysis (rats)
P50HL-17667-04 0022 Study of ischemic heart disease -
Preventing myocardial injury in surgery using
cardiopulmonary bypass (human, rat)
P50HL17667-04 0040 Study of ischemic heart disease -
Core biochemistry-Cardiac metabolism (human)
' P50HL-1767004 0023 Study of ischemic heart disease ■
Energy metabolism in acute myocardial ischemic injury
(dogs)
P50HL-1768204 0018 Study of ischemic heart disease ■
Biochemistry of ischemia-Heart cell and organ culture
(mice. rats, cattle)
R01HL17736-04 Metabolic change during cardiac
ischemia (rats, dogs)
ROlHL-1 789504 Myocardial function and metabolism
following ischemia (rats)
R01HL18206-04 Regulation of metabolism in oxygen
deficient hearts (rats)
ROlHL-18288-04 Intraoperative protection of the
myocardium (dogs, rats)
ROlHL-18527-03 Subcellular response of heart to
functional overload (hamsters, rats)
P01HL18708-03 Oxygen, energy and contractility in
cardiac tissue
' POlHL-18708-03 0005 Oxygen, energy and contractility in
cardiac tissue ■ Cytosolic calcium homeostasis and
bioenergetics of cardiac tissue (animals)
' POlHL-18708-03 0007 Oxygen, energy and contractility in
cardiac tissue • Surfaces, energy requirements, and
contractile proteins of cardiac cell in vitro
* POlHL-18708-03 0010 Oxygen, energy and contractility in
cardiac tissue - Tissue oxygen utilization (rats, dogs)
* ROlHL-18933-03 Energy output and efficiency of left
ventricle (dog)
* POlHL-19242-02 0001 Study of vascular smooth muscle -
Energy metabolism and protein turnover in vascular smooth
muscle (rats)
* ROlHL-19366-03 Renal Starling forces in experimental
conditions (rats, rabbits)
* ROlHL-19461-03 Myocardial energetics in hypertrophy and
heart failure (rabbits)
ROIHL-20286-02 Interventions to improve cardiac function
in ischemia (dogs)
ROlHL-20369-03 The effect of alcohol on the heart (rats)
* ROlHL-20484-03 Effects of diabetes on cardiac function
and metabolism (rats)
* ROlHL-20544-02 Integrated regulation of myocardial
energy metabolism (rats, guinea pigs)
* POlHL-20552-02 0010 The development and regression of
cardiac hypertrophy - Energy metabolism in the
hypertrophied heart animals
* POlHL-20592-02 0001 Cell biology of cardiac and
skeletal muscle - Molecular mechanism of muscle
contraction (animals)
* ROlHL-21209-02 Alterations of metabolism in ischemic
myocardium (swine)
ROlHL-2150002
stress (dogs)
Performance of respiratory muscles under
The mechanical basis of myocardial
RGlHL-21570-01
energetics (cats)
ROlHL-2 1849-02 Control of sodium transport and cellular
respiration (toad bladder)
ROlHL-2223901 The molecular basis of electrical
excitability (chick embryos, rats)
ROlHL-22290-01 Cardiac energy metabolism and protein
synthesis (mice)
Cardiac function and metabolism in
Performance of respiratory muscles under
Lung metabolism and alveolo-capillaiy
BIO
POlHL-22619-01 0010 Cellular mechanisms of heart
failure - Mitochondria in heart and smooth muscle (rabbits,
rats, dogs)
ROlHL-22729-01 Intracellular degradation of newly
synthesized collagen (human, chick, rabbit)
ROlHL-2298117 Membrane-associated functions in
microorganisms (bacieria, protozoa)
ROIHL 23240-01 Pulmonary vascular muscle metabolism
and contractility (rats, cattle)
BIOENERGETICS, HIGH ENERGY COMPOUNDS
POlHL-1131012 0063 Mechanisms of cardiovascular
disease - Myocardial function, metabolism and cellular
integrity after heart surgery (dogs)
P01HL11351 12 0015 Cellular and molecular
mechanisms of myocardial function - Effects of hypoxia
and ischemia on ion exchange and heart function (rabbits)
ROlHL-14523-07 Generation and regulation of force in
smooth muscle (animals)
** ROlHL-15104-07 A mechanism for oxidative
phosphorylation
ROlHL-15983 04 Regional myocardial blood flow (dogs)
ROIHL- 17629-03 Developmental aspects of cardiovascular
function (human, cats, rabbits)
P50HL-1767004 0023 Study of ischemic heart disease ■
Energy metabolism in acute myocardial Ischemic injury
(dogs)
ROIHL' 17853-03 Peripheral circulation in heart failure
(animals)
POIHL 1870803 0010 Oxygen, energy and contractility in
cardiac tissue - Tissue oxygen utilization (rats, dogs)
ROlHL-20177-02 Effects of erythrocyte deformability on
tissue perfusion (rats)
ROlHL-2028602 Interventions to improve cardiac function
in ischemia (dogs)
POlHL-20552-02 0010 The development and regression of
cardiac hypertrophy ■ Energy metabolism in the
hypertrophied heart animals
R23HL-21393-01 Cardiac adaptation to aging and stress
(rats)
ROlHL-2 148201
diabetes (rats)
ROlHL-21500-02
stress (dogs)
R23HL-21853-01
permeability (rats)
ROlHL-22470-01 Liposome myocardial uptake in infarct
and ischemia (dogs. rats, mice)
POlHL-22619-01 0010 Cellular mechanisms of heart
failure - Mitochondria in heart and smooth muscle (rabbits,
rats, dogs)
** R01HL-2314001 Determinants of irreversible ischemic
injury in heart (dog, rat)
ROlHL-23205-01 Contraction of pulmonary vascular
smooth muscle (cat)
BIOENGINEERING
SEE BIOMEDICAL ENGINEERING
BIOENGINEERING AND APPLIED PHYSIOLOGY
STUDY SECTION
SEE PHYSIOLOGY (APPLIED) AND ORTHOPEDICS STUDY
SECTION
BIOEQUIVALENCE OF DRUGS
SEE DRUGS, PHARMACOLOGY, BIOAVAILABILITY
BIOETHICS
SEE HEALTH SOCIAL CONTROL
BIOFEEDBACK CONDITIONING (TRAINING)
SEE PSYCHOLOGY, CONDITIONING. AUTOGENIC AND INTERNAL
CONTROL
BIOGENIC AMINES, NEURAL
SEE NEUROTRANSMITTERS (GENERAL)
BIOLOGICAL BASIS (CORRELATES) OF BEHAVIOR
SEE PSYCHOBIOLOGY. PSYCHOPHYSIOLOGY
BIOLOGICAL BATTERIES, FUEL CELLS
SEE BIOMEDICAL ENGINEERING. BIOLOGICAL POWER
SYSTEMS
BIOLOGICAL CLOCKS, RHYTHMS
SEE BIOPERIOOICITY, BIOLOGICAL CLOCKS
BIOLOGICAL CONTROL AND PROCESSING OF
INFORMATION
SEE INFORMATION PROCESSING AND CONTROL (BIOLOGICAL)
BIOLOGICAL EFFECTS OF PESTICIDES
SEE PESTICIDES BIOLOGICAL EFFECTS (GENERAL)
BIOLOGICAL MODELS
SEE MODELS, BIOLOGICAL
BIOLOGICAL POWER SOURCES
SEE BIOMEDICAL ENGINEERING. BIOLOGICAL POWER
SYSTEMS
BIOLOGICAL PREPARATIONS AND
STANDARDIZATION
SEE ALSO IMMUNOLOGICAL PREPARATIONS
(GENERADdNCLUDING CERTIFICATION AND
STANDARDIZATION)
(contd)
I
(
•Excludes routine methodology OR covers only general projects which preclude indexing at
••Oriented significantly to above subject-
the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
BIO
25
BIO
Slf MSO PIANIS EXTRACTS. MfOICINAl PUNTS
*■ NOIHH SJ0.)!i04 lucloi VIII inliibitori in p<iti«i\t:i wilti
hemophilia
** N01HB8?924 00 Soufca ol human utinaiy •lythiopoiotin
** rOIHlO63:>0 1/ 0018 Hamoslasis igstaich pioniam
pioiect Vaiienlj ol taclois IX (human, cattle)
" ROIHL IOb82 \'2 Thtombosis and homostasis Analysis,
methods and standards (human, cattle, venom)
" ROIHL 10880 13 Pufilication ol human eiythropoietin loi
reseaich use
** ROIHL 13160 08 Human thrombin (also cattle)
ROIHL I3!i8' 06 Synthesis ol renin inhibitors and analog
phosphatides (rats)
■* ROIHL 13881 08 The American Red Cross National
Fractionation Center
** ROIHL 14262 07 Leukocyte proteases and their lun(
targets (human, do|S. rabbits)
POIHL 15S960S 0007 Coagulation. Iibrinolysis,
hemostasis and hepatitis Structural studies and
Iractionation of urokinase (human)
ROIHL 1663304 Chemistry and biology o< factor IX
activator (human, mice, rats)
** ROIHL 1667505 Human urinary erythropoietin collection
ROIHL 17726 03 Bacterial heparinase in diagnostic
coagulation studies
POIHL 1781304 0008 Lung disease and the oxygenation
of blood and tissue Pulmonary regulation ol systemic
blood pressure (human, rabbits, rats)
** ROIHL 1861804 Purification and function of human HMW
kininogen
ROIHL 1982002 The chemistry and biological effects of
heparin (Rhesus, human, other mammals)
ROIHL 22402 01 Heparin biophysical, chemical and
biological aspects (mice, human)
NOIHR 72920 01 Identify and quantify cystic fibrosis
factors (human)
BIOLOGICAL RHYTHMS, CLOCKS
SEE BIOPERIODICITY, BIOLOGICAL CLOCKS
BIOLOGICAL TRANSPORT
SEE ALSO AimiNO ACIDS TRANSPORT (GENERAL)
SEE ALSO CARBOHYDRATES TRANSPORT (GENERAL)
SEE ALSO FAHY ACIDS TRANSPORT (GENERAL)
SEE ALSO LIPIDS TRANSPORT
SEE ALSO NERVOUS SYSTEIVI, NEURONS, AXOPLASMIC FLOW
SEE ALSO PROTEINS TRANSPORT
SEE ALSO RESPIRATORY GAS TRANSPORT
** POlHL-0683517 0028 Cardiovascular disease ■ Studies
in thrombosisfibrinogen in fibrin transport (human)
** R01HL12647-08 Inactivation of norepinephrine in vascular
tissue
R01HL13909-27 Physiochemistry and immunology of
macromolecules
ROlHL-15270-Oe Local mechanical properties of the aortic
tissue (dogs, pigs)
R01HL-16219-05 Mechanisms of atherogenesis in chronic
uremia (human, rats)
R01HL16714-05 Endothelial cell communication in
homeostasis (human, mammals)
** ROlHL-1691604 0011 The role of albumins in lung v»ater
accumulation - Whole body distribution and exchange of
albumin (rabbits, human, monkeys)
** POIHL-1742105 0001 Regulation and exchange in the
microcirculation - Mass transfer and microcirculatory
function (rats)
ROlHL-17895-04 Myocardial function and metabolism
following ischemia (rats)
ROlHL'18010-04 Capillary transport of large molecules
(dogs, sheep)
R01HL-2a62202 Pulmonary uptake and accumulation of
drugs (rabbits, rats)
ROlHL-20989-01
(sheep, dogs)
** ROlHL-21429-02
mammals)
** ROlHL-21438-02 Structure and permeability of arterial
endothelium (pigs)
ROlHL-22077-01 Vasoactive amine disposition in cultured
endothelium (rabbits)
BIOLOGICAL TRANSPORT, ACTIVE TRANSPORT
SEE ALSO GASTROINTESTINAL FUNCTION, ABSORPTION-
TRANSPORT (GENERAL)
SEE ALSO KIDNEY FUNCTION. RENAL TUBULAR TRANSPORT
** R01HL-04457-20 Cellular aspects of active transport (fish.
rabbits, anurans. turtles)
** POlHL-06664-17 0039 Cardiopulmonary function in
remediable vascular disease - Transepithelial active
transport and cell volume regulation (frogs)
POlHL-07896-15 0049 Environmental biomedical research
program - Effects of hyperbaric oxygen and pressure on
cerebral enzymes (rats)
ROlHL-0889314 Structure and function of membrane
proteins (human)
ROlHL-09364-14 Ion transport by heart mitochondria
(cattle, rat. rabbit)
R01HL-10503-13 Cardiac ion transport and ullrastructure
(rats, guinea pigs, rabbits)
M POlHL-1215711 Functions and mechanisms of cell
membrane ion transport
Pathophysiology of bronchial asthma
Transport of LDL in arterial wall (human,
" POIHI 12157 II 0033 lunciian\ and mnchanltms of cell
inenibidiitt ion transport liniiiunology aspects of active
Na K liansport in sheep red cell (also human, mice)
POIHI 1215/ II 0055 Functions and mechanisms of cell
membrane ion transport Growth and development ol
synthetic strand heart cells in culture (chick embryo)
" ROIHI 13256 08 Ammo acid transport by red cell
membranes (pigeons)
ROIHL 14092 0/ Homeostalic regulation ol plasma choline
(rats, dogs, chickens)
POIHI 1438807 0192 Regulation ol the circulation in
pathological states Renal tubular sacretjon ol magnesium
(rats)
POIHL 14414 07 0016 Environmental influences on
cardiorespiratory and cellular functions Effects of
pressure on membrane and cellular function (human,
rabbits)
POIHL 15835 06 0011 Study of muscles related to heart
disease Energetics and mechanism of muscle contraction
(frogs, rabbits)
ROIHL 15852 06 Vascular ion transport and hypertensive
mechanisms
ROIHL 16101 05 Protein lipid interaction (bacteria,
models)
POIHL 16117 05 0005 Ion movements and membranes in
cardiovascular control Properties of isolated cell
membranes (rabbits, cats)
** P60HL1726904 0019 National heart and blood vessel
research and demonstration center Sarcoplasmic
reticulum (dog. rabbit, hamster, cat)
•• P50HL 1764604 0012 Study ol ischemic heart disease •
Role of microcirculation in progression of myocardial
ischemic injury (rat)
ROIHLI 779604 Importance of aminosugars in digitalis
activity (cats, rabbits)
** R01HL1787904 Molecular structure of the ouabain
sensitive ATPase (dogs)
" R01HL1803803 Structure and function of heart
mitochondria (cattle)
POIHL 18208-04 0001 Center for the study of blood cell
rheology - Physiological basis of reversible erythrocyte
shape change (human, firefly)
P01HL1820804 0005 Center for the study of blood cell
rheology - RBC deformability and capillary flow
interrelations (human, mice)
ROlHL-19639-02 Permeability transients of carriers,
channels and heart
ROlHL-20622-02 Pulmonary uptake and accumulation of
drugs (rabbits, rats)
ROlHL-20725-02 Mechanisms and cellular functions of ion
transport
R23HL'21150'02 Regulation of airway mucous glands and
ion transport (dogs, ascaris)
*' ROlHL-2311501 Regulation of active sodium transport
(frogs, rats)
ROlHL-23138-01 Myocardial ischemia (dogs, rats, chick
embryo)
BIOLOGICAL TRANSPORT, ACTIVE TRANSPORT,
CARRIER MEDIATED PERMEATION
P60HL-15999-05 0014 Miami comprehensive sickle cell
center - Biochemical and morphological parameters of
sickle cells (human)
ROlHL-22135-01 Control of calcium fluxes across cardiac
membranes (dogs, rabbits, guinea pigs)
BIOLOGICAL TRANSPORT, ACTIVE TRANSPORT,
ION PUMPS
SEE ALSO BIOLOGICAL TRANSPORT, ION EXCHANGE AND
TRANSPORT, ION CARRIERS (lONOPHORES)
** ROIHL-01974-24 Ion-pump in the erythrocyte (rabbits,
guinea pigs)
POlHL-06285-18 0211 Cardiovascular-respiratory
physiology and biochemistry - Purple membrane of
Halobacteria
*♦ P01HL-11310-I2 0102 Mechanisms of cardiovascular
disease - Cardiac membrane and ion mobility (dogs)
** P01HL12157-11 0054 Functions and mechanisms of cell
membrane ion transport - Simulation of electrogenic ion
transport in cardiac muscle
** P01HL-I2157-11 0060 Functions and mechanisms of cell
membrane ion transport - Ion transport and electrical
properties of giant-celled aiga
ROlHL-15793-06 Molecular aspects of erythrocyte
membrane resealing (human)
ROlHL-19995-02 Sensory transduction in cardiac
mechanoreceptors (cats, frogs, rats)
BIOLOGICAL TRANSPORT, ACTIVE TRANSPORT,
ION PUMPS, CALCIUM PUMP
** POlHL-06308-18 0025 Mechanisms and therapy of
circulatory disease - Subcellular calcium pools in the
genesis of arrhythmias (dogs)
** POlHL-06308-18 0035 Mechanisms and therapy of
circulatory disease - Mechanisms for electrophysiological
changes in myocardial infarction (dogs)
POlHL-06664-17 0036 Cardiopulmonary function in
remediable vascular disease - In vitro studies on the
mechanism of ischemic damage to cells (rabbits)
ROlHL-0850815 Cardiac conductivity and automaticity
(human, dogs, rabbits)
ROlHL-09234-13 Amino acids of contractile proteins of
failing hearts (dogs, hamsters)
POIMI 11151 17 0002 Cellular and molxulai
mechanisms rif myoraidial lunclion ifferls uf hypuiia
and isr.hrmia on ionic eichange (rats, labfjitt)
POIHI 11351 12 0004 Cellular and molecular
mechanisms ol myoiaidial lunilion Molecular
mechanisms ol contiailile function and diffeienlialion
(animals)
POIHI 1 1 351 12 0009 Cellular and molecular
mechanisms of myocardial function Myocardial membrane
surface coat (rats, rabbits)
POIHI 11351 12 0010 Cellular and molecular
mechanisms of myocardial function Basic ionic (ichangc
studies (rats)
POIHL 11351 12 0011 Cellular and molecular
mechanisms of myocardial function Comparative
contractile tissue studies (animals)
POIHL 1 1351 12 0013 Cellular and molecular
mechanisms of myocardial function Ion exchange in the
perfused septum high resolution technique (rabbits, rats)
ROIHL 11880 10 Physiology and pathology ol blood
platelets (human, dogs)
ROIHL 1218609 Calcium transients in striated muscle
and other cells (mammals, frogs)
POIHL 12373 10 0006 Cardiopulmonary physiology and
pathophysiology Fatty acid metabolism Regulation,
implications (human, mammals, birds)
POIHL 12738 10 0044 Physiologic pharmacology and its
clinical applications Cardioactive drugs and
electrophysiological properties of cardiac cells (sheep)
POIHL 12738 10 0109 Physiologic pharmacology and its
clinical applications Effects of calcium blockers on
skeletal and cardiac muscle (cats)
P01HL12738 10 OHO Physiologic pharmacology and its
clinical applications Physiology and pharmacology of
arrhythmias (dogs)
ROIHL 12774 08 Ionic coupling in activation of cardiac
muscle (frogs, guinea pigs)
ROlHL-13256 08 Ammo acid transport by red cell
membranes (pigeons)
ROlHL-1330608 Pharmacological control of cardiac
membrane currents (cattle, rabbits)
ROIHL 13375 09 Cellular potential changes causing
cardiac arrhythmias (dogs)
ROIHL 13454-08 Behavioral stress and cardiomyopathy
(monkeys, cats)
P50HL-14217-08 0059 Specialized center of research in
thrombosis - Energy metabolism and platelet function
(human)
ROIHL 14775 08 Mechanisms of drug action in vascular
smooth muscle (dog. rabbits)
POlHL-1498507 0012 Adaptation to hypoxia - Direct
effect of hypoxia on pulmonary vascular smooth muscle
(rats, dogs)
PO 1 HL- 1 5 1 9407 0004 Pathophysiology of
cardiopulmonary dysfunction - Specialized electrophysiology
fibers -Electrogenic basis of glycosides (mammals)
ROlHL-15522-06 Influence of mannitol on ischemia
cardiac muscle (dogs, cats, rats)
ROlHL-15580-06 Humoral control of pulmonary and
systemic circulation (animals)
ROlHL-15692-07 Force and speed in skeletal and cardiac
muscle
ROlHL-15764-05 CAMP dependent protein kinase in
cardiac contraction (dogs)
POlHL-15835-06 0018 Study of muscles related to heart
disease - Pharmacology of excitation coupling in muscle
(frog, barnacles)
' P01HL15835-06 0021 Study of muscles related to heart
disease - Fast kinetic studies in muscle subcellular
organelles (animals)
ROIHL- 15888-05 Comparative stereology of the
myocardium (birds, mammals)
P60HL-15999-05 0014 Miami comprehensive sickle cell
center - Biochemical and morphological parameters of
sickle cells (human)
P60HL-16008-06 0018 Wayne State University
comprehensive sickle cell center - Hemoglobin S and RBC
membranes -Pathogenesis of irreversibly sickled cells
R01HL16052-05 Cardiac glycosides-Mechanism of
inotropic action (dogs)
' POlHL-161 17-05 0008 Ion movements and membranes in
cardiovascular control - Arterial smooth muscle calcium
fluxes and contractility (rabbits)
' R01HL16135-05 Mechanisms of cardiac autorhythmicity
(dogs, bats)
ROlHL-1615206 Electrophysiology of neonatal to adult
heart (cats, frogs, guinea pigs)
ROlHL-16240-05 The cardiac histamine receptor (rabbits.
guinea pigs)
ROlHL-16454-03 Vascular muscle reactivity m
hypertension (human, rats)
POlHL-16607-05 Calcium ion and control of
cardiovascular function
' POlHL-16607-05 0001 Calcium ion and control of
cardiovascular function • Bilayer lipid membranes,
antibiotic probes, and SR function
' POlHL-16607-05 0003 Calcium ion and control of
cardiovascular function - Calcium transport in
sarcoplasmic membranes (animals)
* POlHL-1660705 0005 Calcium ion and control of
cardiovascular function - Chemical modifications of the
sarcoplasmic reticulum membranes (rabbits)
(contd)
^Excludes routine methodology OR covers only general projects which preclude indexing at the specific level-
**Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number
BIO
26
POlHL-16607-05 0006 Calcium ion and control of
cardiovascular function - Sarcomere and contractile
dynamics of striated muscle cells (animals)
R01HL1670604 Excitation-contraction coupling and heart
failure (dogs, rabbits)
ROlHL-16710'03 Myocardial subcellular localization of
calcium (dogs)
POIHL'16833'04 0011 Hemoglobin and red cell system In
hemoglobinopathies - Relationship between hemoglobin and
R6C membrane In sickling cells (human, rats)
POlHL-16833-04 0016 Hemoglobin and red cell system in
hemoglobinopathies ■ Calcium-indiced membrane damage
in Hb SS disease (human, animals)
ROlHL-17592 03 Activation and contraction heat in
enlarged hearts (rabbits)
R01HL1763105 Experimental congestive heart failure and
hypertrophy (cats)
ROlHL-17702-04 Electro-optical dyes as probes of heart
excitability
P01HL-I8208-04 0005 Center for the study of blood cell
Theology - RBC detormability and capillary flow
interrelations (human, mice)
ROlHL-18527-03 Subcellular response of heart to
functional overload (hamsters, rats)
POlHL-18575-03 0001 Mechanisms of vascular changes
in hypertension Arteries and resistance vessels in
hypertension (pigs, rats)
P01HL18708-03 0004 Oxygen, energy and contractility in
cardiac tissue - Structural-functional studies on
sarcoplasmic reticulum (rabbits)
P01HL18708-03 0005 Oxygen, energy and contractility in
cardiac tissue Cytosolic calcium homeostasis and
bioenergetics of cardiac tissue (animals)
POlHL-18708-03 0007 Oxygen, energy and contractility in
cardiac tissue Surfaces, energy requirements, and
contractile proteins of cardiac cell in vitro
R01HL18711-03 Electrophysiology of heart cells (rats,
chicks)
ROlHL-18937-03 Cyclic nucleotides and calcium In
platelets (human)
ROIHL 1902703 Calcium and cyclic AMP In causation of
hypertension (rats)
R01HLI9044-03 Effect of drugs on development of
cardiac failure (cats)
ROlHL-1907603 Vagal control of heart rate -A biophysical
model (rabbits)
ROlHL-19082-01 Hypoxia-induced relaxation of vascular
smooth muscle
POlHL-19242-02 0003 Study of vascular smooth muscle -
Vasoactive metabolites from vascular muscle and
parenchymal tissue (animal)
P01HL19242-02 0009 Study of vascular smooth muscle -
Electrophysiology of vascular smooth muscle (rats, chick
embryo)
ROlHL-19461-03 Myocardial energetics in hypertrophy and
heart failure (rabbits)
RClHL-19485-03 Calcium uptake by normal and failed
cardiac ATPase (dogs)
POlHL-1973702 0002 Cellular and molecular aspects of
respiratory physiology - Airway smooth muscle in health
and disease (human, animals)
POlHL-20592-02 0001 Cell biology of cardiac and
skeletal muscle - Molecular mechanism of muscle
contraction (animals)
POlHL-20592-02 0003 Cell biology of cardiac and
skeletal muscle - Cellular magnesium and anion activities
in ion-specific microelectrodes (frogs)
ROlHL-2061002 Nerve growth factor and obstructive
cardiomyopathy (dogs)
ROlHL-21030'01 Calcium regulation and hypertension
(rats)
R01HL-2I038-01 Electrically Induced cardiac EM-
histochemical changes (animals)
ROlHL-21 182-02 Active tension and shortening In cardiac
hypertrophy (rabbits)
R23HL-2121301 A model for calcium homeostasis in
excitable tissue (marine worms)
R23HL-21262-02 Sodium-calcium interactions in
mammalian myocardium (rabbits, cats}
ROlHL-21314-02 Respiratory tract secretion of ions, water
and mucus (human, dogs)
R23HL-21325-02 Sarcomere kinematics in cardiac
contraction (rats, rabbits)
ROlHL-2146901 Active transport and effect of CAOO in
sickle cell (human)
ROlHL-2181202 Actions of drugs and ions on cardiac
membranes (rabbits, guinea pigs)
ROIHL 21850-01 Calcium transport in the hypertrophied
myocardium (rats, animals)
ROlHL-2199501 Protein phosphorylation and adrenergic
effects
ROlHL'22135-01 Control of calcium fluxes across cardiac
membranes (dogs, rabbits, guinea pigs)
ROlHL-2217001 Factors influencing transmission at
adrenergic synpases
ROlHL-22264-01 Regulation of contraction in vascular
smooth muscle (dogs)
ROlHL-22269-01 Excitation-contraction coupling in
enlarged hearts (rabbits)
ROlHL-2235401 Alpha-adrenergic effects on heart
metabolism (rats)
Bronchial mucus production in organ
ROlHL-22444-01
culture (human)
ROlHL-22558-01 pH effect in heart cells -Influence of
cardiac drugs (tissue culture, rats)
M POlHL-22619-01 Cellular mechanisms of heart failure
*• POlHL-22619-01 0002 Cellular mechanisms of heart
failure - Structure of sodium, potassium-adenoslne
triphosphatase (lambs, dogs)
** POlHL-22619-01 0009 Cellular mechanisms of heart
failure - Sarcoplasmic reticulum In cardiac, skeletal and
smooth muscle (rabbits, dogs)
POlHL-22619-01 0010 Cellular mechanisms of heart
failure - Mitochondria in heart and smooth muscle (rabbits,
rats, dogs)
ROlHL-22685-01 Drugs and excitation-contraction coupling
in heart (animals)
** ROlHL-22813-01 Palmitylcarnitlne inhibition of ion pumps
in ischemia (dogs)
ROlHL-22828-01 Adenosine and catecholamine interaction
in the heart (rats)
ROlHL-23128-01 Cardiac contractility-Ischemia and
hypoxia (rabbits, rats)
ROIHL 2314201 Mechanisms of membrane injury In
myocardial ischemia (dog)
ROIHL 23153-01 Mechanisms of altered CA20 transport in
ischemic heart (dog, rabbit)
** ROlHL-23161-01 0002 Biology of myocardial ischemia -
Palmitylcarnitlne inhibition of ion pumps in myocardial
ischemia (dog, sheep)
** ROlHL-2320001 Isolation of CA binding proteins from
erythrocytes (human)
BIOLOGICAL TRANSPORT, ACTIVE TRANSPORT,
ION PUMPS, CHLORIDE PUMP
POlHL-12157-11 0060 Functions and mechanisms of cell
membrane ion transport - Ion transport and electrical
properties of giant-celled alga
ROlHL-13256-08 Ammo acid transport by red cell
membranes (pigeons)
P01HL-14388-07 0167 Regulation of the circulation in
pathological states • Increased reactivity of artery vascular
muscle in spontaneously hypertensive rat
POlHL-14388-07 0168 Regulation of the circulation In
pathological states - Ionic basis of depolarization (rats.
tissue culture)
POlHL-14388-07 0179
pathological states -
Regulation of the circulation In
Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
** POlHL-14388-07 0191 Regulation of the circulation in
pathological states - Regulation of chloride transport in
epithelial membranes (turtles)
ROIHL 18053-03 Intracellular ionic activities In heart
muscle (frogs)
** ROIHL 20365-03 Molecular mechanisms of anion transport
POIHL 20592-02 0003 Cell biology of cardiac and
skeletal muscle - Cellular magnesium and anion activities
in ion-specific microelectrodes (frogs)
" POlHL-2059202 0005 Cell biology of cardiac and
skeletal muscle - Quantitative voltage studies
ROlHL-21 136-02 Ion activities and transport in cardiac
muscle cells (sheep)
ROlHL-21314-02 Respiratory tract secretion of ions, water
and mucus (human, dogs)
BIOLOGICAL TRANSPORT, ACTIVE TRANSPORT,
ION PUMPS, HYDROGEN PUMP
** ROlHL-12774-08 Ionic coupling in activation of cardiac
muscle (frogs, guinea pigs)
BIOLOGICAL TRANSPORT, ACTIVE TRANSPORT,
ION PUMPS, POTASSIUM PUMP
ROlHL-04457-20 Cellular aspects of active transport (fish,
rabbits, anurans, turtles)
ROlHL-08508-15 Cardiac conductivity and automaticity
(human, dogs, rabbits)
P01HL-08e82-lS 0036 Regulation of the cardiovascular
system - Electrolyte transport in myocardium with
hemorrhagic shock (rats)
ROlHL-09906-13 0023 Membrane transport processes in
red blood cells - Cation and anion movements in two sub-
groups of dog erythrocytes
** ROlHL-09906-13 0025 Membrane transport processes in
red blood cells - Mechanism of propranolol induced Ca-
dependent K efflux from human RBCs
POIHL 12157-11 0054 Functions and mechanisms of cell
membrane ion transport - Simulation of electrogenic ion
transport in cardiac muscle
POlHL-12738-10 0080 Physiologic pharmacology and its
clinical applications - Electrophysiology of cardiac muscle
in the mitral valve (monkeys)
POlHL-1273810 0110 Physiologic pharmacology and its
clinical applications - Physiology and pharmacology of
arrhythmias (dogs)
ROlHL-12990-09 Control of antidiuretic hormone secretion
and metabolism (dogs, rats, rabbits)
POlHL-14388-07 0152 Regulation of the circulation In
pathological states - Ion flux alterations in caudal artery in
SHR
POlHL-14388-07 0167
pathological states
Regulation of the circulation in
Increased reactivity of artery vascular
muscle in spontaneously hypertensive rat
BIO
POlHL-14388-07 0168 Regulation of the circulation in
pathological states - Ionic basis of depolarization (rats,
tissue culture)
POlHL-14414-07 0016 Environmental influences on
cardiorespiratory and cellular functions ■ Effects of
pressure on membrane and cellular function (human,
rabbits)
ROIHL 14775-08 Mechanisms of drug action in vascular
smooth muscle (dog, rabbits)
P01HL1519407 0004 Pathophysiology of
cardiopulmonary dysfunction - Specialized electrophysiology
fibers -Electrogenic basis of glycosides (mammals)
ROIHL 16052-05 Cardiac glycosides -Mechanism of
inotropic action (dogs)
ROlHL-16135-05 Mechanisms of cardiac autorhythmicity
(dogs, bats)
ROlHL-16152-06 Electrophysiology of neonatal to adult
heart (cats, frogs, guinea pigs)
ROlHL'17452-04 Depolarization induced cardiac
automaticity (human, animals)
ROlHL-18943-03 Contractile activity of single cardiac cells
ROIHL- 19082-01 Hypoxia-induced relaxation of vascular
smooth muscle
POlHL-19242-02 0003 Study of vascular smooth muscle •
Vasoactive metabolites from vascular muscle and
parenchymal tissue (animal)
R23HL'I9601'01 Cardiac response to chronic metabolic
acidosis (rats)
ROlHL-20 153-02 Intracellular pH and myocardial
electropharmacology (dogs, guinea pigs)
ROIHL 20558-02 Cardiac electrophysiology-Effects of Ions
and drugs
" POlHL-2059202 0006 Cell biology of cardiac and
skeletal muscle - Permeability and ultrastructure of cardiac
nexuses (rabbits, cattle, rats)
POlHL-21016-02 0008 Sickle cell anemia and other
hemoglobinopathies - The clinical variations of sickle cell
anemia
ROlHL-21136-02 Ion act.. .ties and transport In cardiac
muscle cells (sheep)
R01HL-2n79-01 Volume regulation-Role of the membrane
potential (amphiuma)
ROlHL-21294-02 Voltage clamp of isolated cardiac
Purkinje cells (dogs)
ROlHL-22568-01 pH effect in heart cells-Influence of
cardiac drugs (tissue culture, rats)
R23HL-22775-01 Muscarinic receptors in the developing
heart (chick embryo)
** ROlHL-23 115-01 Regulation of active sodium transport
(frogs, rats)
BIOLOGICAL TRANSPORT, ACTIVE TRANSPORT,
ION PUMPS, SODIUM PUMP
ROlHL-04457-20 Cellular aspects of active transport (fisb,
rabbits, anurans. turtles)
** P01HL0628518 0193 Cardiovascular-respiratory
physiology and biochemistry - Hormonal regulation of
sodium transport -Aldosterone (rats, toads)
POlHL-06285-18 0194 Cardiovascular-respiratory
physiology and biochemistry - Hormonal regulation of
sodium transport -RNA synthesis (rats, toads)
** POlHL-0628518 0195 Cardiovascular-respiratory
physiology and biochemistry - Thyroid thermogenesis and
sodium transport (rats)
** P01HL06285-18 0196 Cardiovascular-respiratory
physiology and biochemistry - Hormonal regulation of
sodium transport -Epithelial cell membranes (toads)
** POlHL-06285-18 0197 Cardiovascular-respiratory
physiology and biochemistry - Micropertusion and
micropuncture of renal tubules (hamsters, desert rats)
** POlHL-06285-18 0199 Cardiovascular-respiratory
physiology and biochemistry - Renal tubular reabsorption of
sodium chloride (hamsters, rabbits)
** POlHL-06285-18 0200 Cardiovascular-respiratory
physiology and biochemistry - Medullary counter-current
system (animals)
** POlHL-06308-18 0035 Mechanisms and therapy of
circulatory disease - Mechanisms for electrophysiological
changes in myocardial infarction (dogs)
POlHL-06664-17 0037 Cardiopulmonary function in
remediable vascular disease - Salt and water balance of
cells and tissues (rabbits)
** POlHL-06664-17 0039 Cardiopulmonary function in
remediable vascular disease - Transepithelial active
transport and cell volume regulation (frogs)
** P01HL06664-17 0040 Cardiopulmonary function in
remediable vascular disease - The coupling of ion transport
to metabolism (toads)
** POlHL-07896-15 0029 Environmental biomedical research
program - Oxygen-helium diving resulting in high pressure
nervous syndrome (human, animals)
** POlHL-07896-15 0030 Environmental biomedical research
program - Narcosis caused by inert gases at raised
pressures (human, animals)
POlHL-08682-15 0036 Regulation of the cardiovascular
system - Electrolyte transport in myocardium with
hemorrhagic shock (rats)
ROlHL-08893-14 Structure and function of membrane
proteins (human)
ROlHL-09906-13 0023 Membrane transport processes in
red blood cells - Cation and anion movements in two sub-
groups of dog erythrocytes
(contd)
'Excludes routine methodology OR c(>vers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects
See Appendix for investigator's name and grant number
■'y.y3»mm3ur^K^^ji-jr '.
BIO
27
BIO
Regulation of the circulation in
Renal tubular secretion of magnesium
ROINl 1089' I? Ettacti o( hormonal on cardiac
•lactiogenesis (rabbits* guinea pigs, dogs)
" ROIHL 10914 10 Ranal sodium transport in iiperimental
aldostaionism (dogs)
POIHL lUbl 12 0001 Cellular and molecular
mechanisms ot myocardial function Ionic control of
myocaidial contiactility (animals)
POIHL ll3bl I? OOIS Cellulai and molecular
mechanisms ol myocardial function Itfects of hypoxia
and ischemia on ion eichange and heart function (idbbits)
** POlHt 12157 II 0033 functions and mechanisms of cell
membrane ion transport Immunology aspects ol active
Na K liansporl in sheep led cell (also human, mice)
POlffl 12157 11 00S4 Functions and mechanisms ot cell
membiane ion transport Simulation of electrogenic ion
transport in cardiac muscle
POlltl 12738 10 0044 Physiologic pharmacology and its
clinical applications Cardioactive drugs and
electrophysiological properties ol cardiac cells (sheep)
POIHL 12738 10 0136 Physiologic pharmacology and its
clinical applications
ROIHL 12990 09 Control of antidiuretic hormone secretion
and metabolism (dogs. rats, rabbits)
ROIHL 132S6'08 Ammo acid transport by red cell
membranes (pigeons)
POIHL 1438807 0152 Regulation of the circulation in
pathological states Ion flux alterations in caudal artery in
SHR
POIHL 1438807 0192
pathological states
(rats)
P01HL1441407 0016 Environmental influences on
cardiorespiratory and cellular functions Effects ol
pressure on membrane and cellular function (human,
rabbits)
ROIHL 14899 07 Mechanism and prevention of cardiac
arrtiythmias (dogs)
P50HL'1S061'07 0005 Response of lung to injury - Airway
smooth muscle in health and disease (dogs, guinea pigs)
R01HL'ie052'05 Cardiac glycosides-Mechanism of
inotropic action (dogs)
•• P60HL1 726904 0017 National heart and blood vessel
research and demonstration center - Cell membrane (dogs.
rabbits)
P60HL'1726904 0018 National heart and blood vessel
research and demonstration center - Mitochondria and
energetics (rabbits, dogs)
P60HL-17269'04 0022 National heart and blood vessel
research and demonstration center - Medicinal chemistry
(rabbit, dog. guinea pig)
ROIHL 17702-04 Electro-optical dyes as probes of heart
excitability
POlHL'l 787 1-04 0013 Kidney, sodium, cardiac output.
arterioles and hypertension - Perfusion pressure and renal
sodium excretion (rats)
** R01HL-I8 185-04 Cardiac glycosides and diuretics -Role of
NaO pump (dogs)
ROlHL-18943-03 Contractile activity of single cardiac cells
R01HL-19216-03 Characterization of cardiac pacemaker
activity (cat. dog. rabbit)
R01HL'19320-03 Angiotensin neuropharmacology-
Relatlonship to sodium
ROlHL-19366-03 Renal Starling forces in experimental
conditions (rats, rabbits)
ROlHL-19398-03 Regional conduction abnormalities and
arrhythmias (dogs)
R23HL-19601-01 Cardiac response to chronic metabolic
acidosis (rats)
ROlHL-20153-02 Intracellular pH and myocardial
electropharmacology (dogs, guinea pigs)
R01HL-2017e-02 Biochemistry and genetics of salt
hypertension (rats)
ROlHL-20558-02 Cardiac electrophysiology-Effects of ions
and dr^gs
POlHL-20581-01 0001 Vascular neuroeffector
mechanisms in health and disease - Vascular neuroeffector
mechanism (rabbits)
ROlHL-21014-01 Mechanism of the inotropic action of
cardiac glycosides
ROlHL-21179-01 Volume regulation-Role of the membrane
potential (amphiuma)
ROlHL-21217-01 Ion and 5-hydroxytryptamine transport by
platelets
** R23HL-21262-02 Sodium-calcium interactions in
mammalian myocardium (rabbits, cats)
ROlHL-21314-02 Respiratory tract secretion of ions, water
and mucus (human, dogs)
** ROlHl-21342-02 Isolation and analysis of sodium channel
from heart (frogs)
ROlHL-21672-01 Antiarrhythmic drug action on VMAZ of
cardiac cells
ROlHL-21742-01 Frequency-dependent drug actions in
cardiac muscle (rabbits)
*• ROlHL-22239-01 The molecular basis of electrical
excitability (chick embryos, rats)
R23HL-22245-02 Functional characteristics of atrial
receptors (rats)
ROlHL-22264-01 Regulation of contraction in vascular
smooth muscle (dogs)
ROlHL-22568-01 pH effect in heart cells-Influence of
cardiac drugs (tissue culture, rats)
ROIHL 22685 01 Diugs and excitation contraction coupling
II) heart (animals)
** ROIHI 2281301 Pilmitylcainitine inhibition ol ion pumps
in ischemia (dogs)
R23Ht 27882 01 Modulation hy disease of ettecl of
turosemide in man
** ROIHL 231 15 01 Regulation ol active sodium transport
(liogs. rats)
BIOLOGICAL TRANSPORT, ACTIVE TRANSPORT,
ION PUMPS, SODIUM-POTASSIUM PUMP
ROIHL 01974 24 Ion pump in the erythrocyte (rabbits,
guinea pigs)
POIHL 06308 18 0025 Mechanisms and therapy of
circulatory disease Subcellular calcium pools in the
genesis of arrhythmias (dogs)
POIHL 063 14 17 0055 Immunologic mechanisms in
cardiovascular disease Genetics and cell biology
POIHL 06664 17 0036 Cardiopulmonary function in
remediable vascular disease In vitro studies on the
mechanism of ischemic damage to cells (rabbits)
POIHL 07896 15 0032 Environmental biomedical research
program Fluorometry study of brain exposed to hyperbaric
oxygen (dogs, cats)
ROIHL 09234 13 Ammo acids of contractile proteins ol
failing hearts (dogs, hamsters)
** ROIHL 09906 13 0018 Membrane transport processes in
red blood cells Rapid photolytic release of ATP from a
protected analog NaK pump of R6C ghosts
*• ROIHL 09921 13 Mechanisms related to congestive heart
failure (dogs, human, rat)
•* P01HLn35112 0009 Cellular and molecular
mechanisms of myocardial function Myocardial membrane
surface coat (rats, rabbits)
** POlHL-11351-12 0010 Cellular and molecular
mechanisms of myocardial function Basic ionic exchange
studies (rats)
** POlHL-11351 12 0011 Cellular and molecular
mechanisms of myocardial function - Comparative
contractile tissue studies (animals)
** R01HL12774-08 Ionic coupling in activation of cardiac
muscle (frogs, guinea pigs)
R01HL-I2839-09 Flow, transport and membrane
phenomena in blood (human)
ROlHL-12990-09 Control of antidiuretic hormone secretion
and metabolism (dogs. rats, rabbits)
ROlHL-13375-09 Cellular potential changes causing
cardiac arrhythmias (dogs)
POlHL-14388-07 0167 Regulation of the circulation in
pathological states - Increased reactivity of artery vascular
muscle in spontaneously hypertensive rat
POlHL-14388-07 0168 Regulation of the circulation in
pathological states - Ionic basis of depolarization (rats.
tissue culture)
POlHL-14388-07 0179
pathological states
Regulation of the circulation in
Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
POlHL-14388-07 0223 Regulation of the circulation in
pathological states - Kallikrein-kinin system in hypertension
(rats)
R01HL-U526-07 Oral contraceptives and hypertension
(rats)
POlHL-14985-07 0012 Adaptation to hypoxia - Direct
effect of hypoxia on pulmonary vascular smooth muscle
(rats, dogs)
R0IHL-1SS22-06 Influence of mannitol on ischemia
cardiac muscle (dogs. cats, rats)
POlHL-15835-06 0018 Study of muscles related to heart
disease - Pharmacology of excitation coupling in muscle
(frog, barnacles)
R01HL-ie3 18-21 Biochemistry and pharmacology of Na-K
transport
ROlHL-16454-03 Vascular muscle reactivity in
hypertension (human, rats)
ROIHL 16549-04 Cardiotonic steroid-NaK ATPase
interactions (cattle)
ROlHL-16567-04 Differentiation of the heart-cell
membrane (mice, chick)
ROlHL-17451-05 Digitalis effects on cardiac automaticity
mechanisms
ROlHL-17555-05 Distribution and metabolism of labeled
digitaloids (dogs, guinea pigs)
R01HL-17796-04 Importance of aminosugars in digitalis
activity (cats, rabbits)
R01HL-180S3-03 Intracellular ionic activities in heart
muscle (frogs)
POlHL-18575-03 0001 Mechanisms of vascular changes
in hypertension - Arteries and resistance vessels in
hypertension (pigs, rats)
ROlHL-18598-03 Role of Na, K-ATPase inhibition on
digitalis action
ROlHL-187 11-03 Electrophysiology of heart cells (rats.
chicks)
ROlHL-18798-04 0001 Nervous and ionic factors in
sudden cardiac death - Potassium loss during myocardial
ischemia (rabbits)
ROlHL-190 76-03 Vagal control of heart rate-A biophysical
model (rabbits)
R01HL-19129-04 Cardiac glycosides-Mechanisms of
cellular actions
POlHL-19737-02 0002 Cellular and molecular aspects of
respiratory physiology - Airway smooth muscle in health
and disease (human, animals)
ROIHL 19933 07 Membrane and led oil dytlunrlion m
hemolytic annfnia (human)
" ROIHI 20762 02 Cardiac (lycotidet and the machaniin
ol the lodium polattium pump
POIHI 7059? 07 0005 Cell biology of cardiac and
skeletal muscle Quantitative voltage itudwt
** ROIHL 70/11 01 Structure function ralalionthipt in rtd
cell NA K pumps (goats)
P60HL 70985 01 0004 Northern California sickle cell
center Characlen/alion ol irreversibhr sickled cells
(human)
ROIHI 71014 01 Mechanism of the inotropic action of
cardiac ghfcosides
ROIHL 21136 02 Ion activities and transport in cardiac
muscle cells (sheep)
*• R23HL21I96 02 Digitalis induced arrhythmia and NAO RO
atpase activity (dogs)
RCIHL 21525 02 Effect of cations, anions and water upon
blood vessels (dogs, rats)
ROIHL 21995 01 Protein phosphorylation and adrenergic
effects
M POIHL 2261901 Cellular mechanisms of heart failure
•* POIHL 2261901 0001 Cellular mechanisms of heart
failure Cell membrane isolation and reconstitution (dogs,
lambs)
" POIHL 22619-01 0002 Cellular mechanisms of heart
failure Structure of sodium, potassium adenosine
triphosphatase (lambs, dogs)
** POIHL 22619 01 0003 Cellular mechanisms of heart
failure Digitalis induced inotropy in myocardial ischemia
heart failure (animals)
** POIHL 22619-01 0004 Cellular mechanisms of heart
failure Mechanism of action of Na. K-ATPase (sheep,
cattle)
ROIHL 22951-01 Studies on the affect of vitamin E on
platelets (human, rats)
** ROIHL 2316101 0002 Biology of myocardial ischemia -
Palmitylcarnitine inhibition of ion pumps in myocardial
ischemia (dog. sheep)
ROIHL 2331201 Hemodynamics and vasoactivity in renal
hypertension (human, dogs)
** ROlHL-23600-01 Ions, water, and hypertension (human,
dogs, rats)
BIOLOGICAL TRANSPORT, ACTIVE TRANSPORT,
PINOCYTOSIS
SEE ALSO CELL INGESTION. PHAGOCYTOSIS
R01HL04512 19 Ultrastructural studies of capillary
permeability (rats, mice)
P01HL-0880S-15 0048 Regulation of ventilation and
pulmonary circulation - Permeability of alveolo-Capillary
membrane in normal pulmonary hypertensive lung
ROlHL-10642-18 Plasma cholesterol metabolism (human,
macaca)
ROlHL-11154-12
(human)
ROlHL-12421-10
(dogs, baboons)
P50HL-14230-07 0092 A/S SCOR-Lipids. atherosclerosis
and thrombosis - Tissue lipids-Cell culture studies
(human)
P50HL-14237-07 0002 Support for arteriosclerosis center
- Interactions of lipoprotein particles with vascular surtace
(human, rat)
** ROlHL-16666-05 Micropinocytosis in isolated capillary
endothelium
P01HL-16748-05 0001 Cellular and immunological basis
of pulmonary diseases - Mechanisms of alveolar
macrophage function and dysfunction (human, rabbits)
ROlHL-18010-04 Capillary transport of large molecules
(dogs, sheep)
ROlHL-19721-03 Lung inflammation-Lysosomal proteases
and liposomes (human, rabbits)
POlHL-20948-02 0002 Molecular basis of cholesterol
metabolism - LDL pathway in cell lines with informative
properties other than fibroblasts
ROlHL-21120-02 Membrane dynamics in alveolar
macrophages (rabbits)
" R23HL-21411-02 Control of extracellular lysosomal
hydrolase levels (rats)
R01HL-217S6-11 Vascular disease-Cytochemistry and
ultrastructure (human, rats. mice, hamsters)
ROlHL-22170-01 Factors influencing transmission at
adrenergic synpases
** ROlHL-22463-02 Pinocytotic vesicles and pulmonary
edema (rats)
ROlHL-22924-01 The airway mucosal barrier (guinea pigs)
BIOLOGICAL TRANSPORT, FLUID EXCHANGE
AND TRANSPORT
SEE ALSO BIOLOGICAL TRANSPORT. PASSIVE TRANSPORT.
DIFFUSION
SEE ALSO BIOLOGICAL TRANSPORT. PASSIVE TRANSPORT.
OSMOSIS
SEE ALSO BLOOD OSMOTIC PRESSURE
SEE ALSO BODY FLUID BAUNCE THERAPY
SEE ALSO CELL FLUIDS. OSMOTIC PRESSURE
" ROlHL-09921-13 Mechanisms related to congestive heart
failure (dogs, human, rat)
" P50HL-14218-07 0017 Pulmonary SCOR-Newborn lung
center - Transvascular fluid exchange, vasoactive mediators
in RDS (sheep, cat)
(contd)
Blood group antigens and antibodies
Pathophysiology of circulatory shock
'Excludes nwtine methodotogy OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
BIO
** ROlHL-15593-05 Prolonged extracorporeal cardiopulmonary
support (ratso sheep, rabbits)
P50HL19153-02 0004 SCOR-Pulmonary edemas -Eitology,
pathogenesis - Physical mechanisms In lung transvascular
transport-Math models (sheep)
M P50HL 19155-02 Pathophysiology of pulmonary edema
P50HL-19155-02 0001 Pathophysiology of pulmonary
edema - Pulmonary edema study unit (human, dog)
** P50HL19155-02 0004 Pathophysiology of pulmonary
edema - Physical and chemical effects of multiple
pulmonary emboli (sheep)
** P50HL-19185-02 0004 Pulmonary SCOR -Neonatal
respiratory distress syndromes - Fluid and protein transport
in fetal and newborn lung (sheep, rabbits)
** ROlHL-21314-02 Respiratory tract secretion of ions, water
and mucus (human, dogs)
** ROlHL-21376-02 Blood-gas barrier solute and water
transport (rabbits)
R01HL-2180001 Angiotensin eftects on water Intake and
excretion
** ROlHL-22444-01 Bronchial mucus production in organ
culture (human)
" RO'HL-22569-02 Intestinal secretion-Capillary and tissue
forces (dogs, cats)
BIOLOGICAL TRANSPORT, ION EXCHANGE AND
TRANSPORT
R01HL018I3-25 Regulation of metabolism by drugs and
hormones (rats)
** ROlHL-02835 21 Renal transport carrier for organic
compounds (dogs, rats)
R01HL04457-20 Cellular aspects of active transport (fish,
rabbits, anurans, turtles)
POlHL-06285-18 0189 Cardiovascular-respiratory
physiology and biochemistry - Mucociliary clearance (cats,
dogs)
P01HL0628518 0194 Cardiovascular-respiratory
physiology and biochemistry ■ Hormonal regulation of
sodium transport-RNA synthesis (rats, toads)
POlHL-0628518 0197 Cardiovascular-respiratory
physiology and biochemistry - Microperfusion and
micropuncture of renal tubules (hamsters, desert rats)
POlHL-06285-18 0198 Cardiovascular-respiratory
physiology and biochemistry • Renal tubular secretion of
hydrogen ion (animals)
POlHL-06285-18 0200 Cardiovascular-respiratory
physiology and biochemistry - Medullary counter-current
system (animals)
POlHL-0628518 0211 Cardiovascular-respiratory
physiology and biochemistry ■ Purple membrane of
Halobacteria
POlHl-06314-17 0047 Immunologic mechanisms in
cardiovascular disease - Role of intravascular coagulation
(human, animals)
POlHL-06664-17 0040 Cardiopulmonary function in
remediable vascular disease - The coupling of ion transport
to metabolism (toads)
POlHL-0789615 0029 Environmental biomedical research
program ■ Oxygen-helium diving resulting in high pressure
nervous syndrome (human, animals)
" P01HL08682-15 0036 Regulation of the cardiovascular
system - Electrolyte transport in myocardium with
hemorrhagic shock (rats)
ROlHL-08977-14 Quantitation of flow and solute flux in
microvessels (cats, rats)
** ROlHL-0936414 Ion transport by heart mitochondria
(cattle, rat, rabbit)
•* ROlHL-09906-13 0020 Membrane transport processes in
red blood cells - Calibration of a fluorescent probe for
erythrocytes
** ROlHL-09906-13 0022 Membrane transport processes in
red blood cells - Anion transport in dog and cat red cells
ROlHL-09906-13 0023 Membrane transport processes in
red blood cells - Cation and anion movements in two sub-
groups of dog erythrocytes
" ROlHL-09906-13 0024 Membrane transport processes in
red blood cells - Inhibition of sulfate transport in human
RBCs by isothiocyanic acid esters
** ROlHL-10182-13 Circulatory function and electrolytic
metabolism (dogs, human)
POIHL-10436-13 0002 A multidisciplinary study of
congenital heart disease - Myocardial performance,
metabolism and ultrastructure (human, cats, rats)
** ROlHL-10503-13 Cardiac ion transport and ultrastructure
(rats, guinea pigs, rabbits)
ROlHL-10914-10 Renal sodium transport in experimental
aldosteronism (dogs)
M POlHL-11351-12 Cellular and molecular mechanisms of
myocardial function
•• POlHL-1 135112 0001 Cellular and molecular
mechanisms of myocardial function - Ionic control of
myocardial contractility (animals)
*• P01HL-1135M2 0002 Cellular and molecular
mechanisms of myocardial function - Eftects of hypoxia
and ischemia on ionic exchange (rats, rabbits)
** POlHL-1 1351-12 0009 Cellular and molecular
mechanisms of myocardial function - Myocardial membrane
surface coat (rats, rabbits)
*• POlHL-11351-12 0011 Cellular and molecular
mechanisms of myocardial function - Comparative
contractile tissue studies (animals)
28
" POlHL-11351-12 0013 Cellular and molecular
mechanisms of myocardial function - Ion exchange in the
perfused septum high-resolution technique (rabbits rats)
** P01HL-1135M2 0015 Cellular and molecular
mechanisms of myocardial function - Eftects of hypoxia
and ischemia on ion exchange and heart function (rabbits)
POlHL-11351-12 0020 Cellular and molecular
mechanisms of myocardial function - Electrophysiology of
cultured heart cells
POlHL-1 1678-11 0063 Cardiovascular dynamics and their
control - Renin-angiotensin system-Control of renal
hemodynamics, electrolyte excretion
M P01HL-I215711 Functions and mechanisms of cell
membrane ion transport
** POlHL-12157-11 0049 Functions and mechanisms of cell
membrane ion transport - Ouabain-insensitive cation
transport in duck red cells
** POIHL-12157-11 0060 Functions and mechanisms of cell
membrane ion transport - Ion transport and electrical
properties of giant-celled aiga
ROlHL-12990-09 Control of antidiuretic hormone secretion
and metabolism (dogs, rats, rabbits)
R01HLI2997-07 Myocardial defects induced by potassium
depletion (human, rats, cats)
ROlHL-1325608 Ammo acid transport by red cell
membranes (pigeons)
ROlHL-13349-06 Analysis of activation process in heart
muscle (guinea pigs, rabbits, human)
** R01HL-13567-06 Ion transport across cell membranes
(human)
ROlHL-13636-08 Eftects of pharmacologic agents on heart
metabolism (human, rodents)
R01HL-136G6-06 Pharmacology of genesis of cardiac
rhythmicity (rats, cats)
** ROlHL-14133-08 Intrarenal regulation of sodium
reabsorption (dogs, hamsters, rats)
ROlHL-14148-07 0008 The regional circulations - Renal
circulation in hypertensive patients (also dogs)
P50HL-14212-07 0013 Correlated studies of pulmonary
fibrosis ■ Mechanism of beryllium pathogenicity in the lung
(human, rabbit, guinea pig)
** POlHL-14388-07 0168 Regulation of the circulation in
pathological states - Ionic basis of depolarization (rats,
tissue culture)
POlHL-14388-07 0172 Regulation of the circulation in
pathological states - cAMP-dependent protein kinase from
heart and vascular smooth muscle (guinea pigs)
POlHL-14388-07 0175 Regulation of the circulation in
pathological states ■ Functional studies of selected proteins
from cardiac muscle
P01HL14388-07 0179 Regulation of the circulation in
pathological states - Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
POlHL-1438807 0191 Regulation of the circulation in
pathological states - Regulation of chloride transport in
epithelial membranes (turtles)
POlHL-1438807 0192 Regulation of the circulation in
pathological states - Renal tubular secretion of magnesium
(rats)
P01HL14414-07 0016 Environmental influences on
cardiorespiratory and cellular functions - Effects of
pressure on membrane and cellular function (human,
rabbits)
ROlHL-1448308 Energy conservation in heart
mitochondria (cattle, E coll, human)
ROlHL-14523-07 Generation and regulation of force in
smooth muscle (animals)
ROlHL-14720-08 Factors governing the renal excretion of
acid (humans, rats)
ROlHL-14775-08 Mechanisms of drug action in vascular
smooth muscle (dog, rabbits)
ROlHL-14820-07 Factors aftecting physiology of biological
membranes (human)
P60HL-15I57-07 0009 Comprehensive center for sickle
cell disease - Red cell membrane alterations during
sickling (human)
P60HL-15I57-07 0018 Comprehensive center for sickle
cell disease • Red blood cell membrane physiology in sickle
cell anemia (human)
POlHL-15194-07 0004 Pathophysiology of
cardiopulmonary dysfunction • Specialized electrophysiology
fibers-Electrogenic basis of glycosides (mammals)
ROlHL-15668-06 Extracorporeal respiratory gas exchange-
A new approach (dogs)
R01HL-15G92-07 Force and speed in skeletal and cardiac
muscle
ROlHL-15813-05 Cardiac anoxia -Protective eftect of
carbohydrate (dogs)
POlHL-15835-06 0013 Study of muscles related to heart
disease • Cardiac bioenergetics (rats)
** POlHL-15835-06 0018 Study of muscles related to heart
disease - Pharmacology of excitation coupling in muscle
(frog, barnacles)
POIHL-15835-06 0019 Study of muscles related to heart
disease - Vascular smooth muscle-Electron microscopy,
excitation contraction (animal)
P0IHL-15835-0G 0023 Study of muscles related to heart
disease - Cellular basis of the Frank-Starling curve (frogs,
rats)
** ROlHL-15852-06 Vascular ion transport and hypertensive
mechanisms
'Excludes routine methodology OR covers only general proiecls which preclude indexing
"Oriented significantly to above subject
at the specific level
M Grant has subproiects de scribing sped
See Appendix for investigator's name and
BIO
P60HL15999-05 0014 Miami comprehensive sickle cell
center - Biochemical and morphological parameters of
sickle cells (human)
ROlHL-15010-16 Cellular basis of cardiac contractility
(frogs)
M POlHL-16117-05 Ion movements and membranes in
cardiovascular control
** POlHL-16117-05 0003 Ion movements and membranes in
cardiovascular control - Fast kinetic study of calcium
membrane interactions
POlHL-16117-05 0008 Ion movements and membranes in
cardiovascular control • Arterial smooth muscle calcium
fluxes and contractility (rabbits)
ROlHL-16152-06 Electrophysiology of neonatal to adult
heart (cats, frogs, guinea pigs)
** ROlHL-16318-21 Biochemistry and pharmacology of Na-K
transport
ROlHL-16421-08 Determinants of RBC deformability and
capillary flow (human, mice)
ROlHL-16436-04 Role of calcium and thyroxine in heart
function (rats)
ROlHL-16454-03 Vascular muscle reactivity in
hypertension (human, rats)
** POIHL 16607-05 0001 Calcium ion and control of
cardiovascular function - Bilayer lipid membranes,
antibiotic probes, and SR function
** R01HL-I6746-04 Design of ion-selective molecules
POIHL-16833-04 0014 Hemoglobin and red cell system in
hemoglobinopathies - Erythrocyte membrane damage in Hb
SS disease (human)
P60HL-17269-04 0022 National heart and blood vessel
research and demonstration center - Medicinal chemistry
(rabbit, dog, guinea pig)
ROlHL-17411-04 Molecular studies of red blood cell
spectrin (human)
R01HL-I745I-05 Digitalis effects on cardiac automaticity
mechanisms
ROlHL-17452-04 Depolarization induced cardiac
automaticity (human, animals)
ROlHL-17571-03 Study of membrane permeability by NMR
relaxation (human)
P50HL-17648-04 0014 Study of ischemic heart disease ■
Antidysrhythmic drugs and mammalian cardiac Purkinje
fibers (sheep, dog)
P50HL 17669-04 0006 Ischemic heart disease center
(SCOR) - Studies of hypoxic, acidotic and ischemic cardiac
muscle (dogs)
R01HL17702-04 Electro-optical dyes as probes of heart
excitability
POlHL-17871-04 0013 Kidney, sodium, cardiac output,
arterioles and hypertension ■ Perfusion pressure and renal
sodium excretion (rats)
** R01HL-I7878-04 Structural studies of the human
erythrocyte membrane
ROlHL-18003-05 Digitalis-Mechanism and reversal studies
(dog, sheep, duck, guinea pig, human)
ROIHL-18032-03 Development of normal and myopathic
mammalian heart (hamsters)
ROlHL-18038 03 Structure and function of heart
mitochondria (cattle)
** ROlHL-18053-03 Intracellular ionic activities in heart
muscle (frogs)
ROlHL-1814804 Adrenal catecholamine secretion
ROlHL-18199-03 Effects of ions on vascular reactivity
ROlHL-18943-03 Contractile activity of single cardiac cells
ROlHL-19008-02 Carbon dioxide diffusion in lung and
muscle tissues (dogs)
ROlHL-19012-03 Smooth muscle of resistance vessels in
hypertension (rats)
" ROlHL-19129-04 Cardiac glycosides-Mechanisms of
cellular actions
R01HL-19I38-03 Contractile activation of skinned cardiac
cells (mammals)
** ROlHL-19139-03 Dispersion of diffusible indicators in the
body (human, cats, dogs)
P50HL-19157-02 0001 Studies in cystic fibrosis and
bronchiolitis - Laboratory core unit
P50HL-19157-02 0007 Studies in cystic fibrosis and
bronchiolitis - Analysis of cystic fibrosis factors (human)
R23HL-19601-01 Cardiac response to chronic metabolic
acidosis (rats)
ROIHL-19639-02 Permeability transients of carriers,
channels and heart
R01HL-I9673-03 Surgical aspects of shock and hypoxia
(dogs, monkeys, rats)
ROlHL-19674-02 Electrolyte permeability of single
capillaries (frogs)
ROlHL-20153-02 Intracellular pH and myocardial
electropharmacology (dogs, guinea pigs)
ROlHL-20230-02 Analysis of the action potential of
cardiac muscle (sheep)
ROlHL-2036503 Molecular mechanisms of anion transport
** ROlHL-20558-02 Cardiac electrophysiology -Effects of ions
and drugs
M POlHL-20592-02 Cell biology of cardiac and skeletal
muscle
POlHL-20592-02 0004 Cell biology of cardiac and
skeletal muscle - Excitation, conduction and contraction -
Modelling in Purkin/e fibers
** POlHL-20592-02 0013 Cell biology of cardiac and
skeletal muscle - Sarcoplasmic reticulum in skinned
muscle cells (frogs)
(coritdj
fie research aspects
grant number
I
BIO
KOIHL ?0I\\ 01 Sttucluio lunclion idilionships (n red
c«ll NAK pumps (lotitsl
ROIHl ?0'?0 0? Myocirdial piotection duiint
catdiopulmontty bypiss |do(s)
ROIHl 20??S0? Mechanisms and cellulai lunclions ot lun
tiansport
Anesthetic induced myocjididl depirssion
Cellular aspects ol luni iniury (rats.
Ion and S hydroxytryptamine transport by
ROIHl ?0?S4 02
(rabbits)
ROIHl ?08 78 0?
rabbits)
" P60HI 2098S 01 0004 Northern California sickle cell
center Characteriiation at irreversibly sickled cells
(human)
** ROIHl 21136 02 Ion activities and transport m cardiac
muscle cells (sheep)
" R23HI 21150 02 Regulation ol airway mucous glands and
Ion transport (dogs, ascaris)
** ROIHl 2117901 Volume regulation Role o( the membrane
potential (amphiuma)
ROlHL-21195 02 Innervation ol the heart Acetylcholine
receptors (trogs)
•• R01HL2121701
platelets
ROIHL 2129402 Voltage clamp ol isolated cardiac
Purkinie cells (dogs)
** ROIHl 21314 02 Respiratory tract secretion of ions, water
and mucus (human, dogs)
ROIHl 21342 0? Isolation and analysis ol sodium channel
trom heart (Irogs)
ROlHl-2167001 Antiarrhythmic studies on 2substituted
aminoindenes (dogs)
ROlHl-2173501 Electrophysiology alter healed myocardial
inlarction (cats)
R01HL-21742-01 Frequency dependent drug actions in
cardiac muscle (rabbits)
** R23HL-2178301 Ionic control ol contractility in anoxic
myocardium (rabbits, rats)
ROlHl-2184501 Human red cell membrane- Structure and
function
ROlHL-2186018 Factors influencing responses to
adrenergic drugs (guinea pigs, rats, cats)
ROIHL-21995-01 Protein phosphorylation and adrenergic
eWects
♦* R01HL-22008-01 Lett ventrivular calcium content and
contractility (rats)
♦♦ ROlHL-22039-02 Ion transport in cardiac muscle (dogs,
rodents, cattle)
ROlHL-2208802 Metabolic basis for diabetic
microangiopathy (cattle)
** ROlHL-2213501 Control ol calcium lluxes across cardiac
membranes (dogs, rabbits, guinea pigs)
ROlHL-2213702 Structure-lunction pathology ol isolated
heart cells (mice, rats)
ROlHL-2223102 Modulation ol calcium control ol cardiac
myolibriis (rats)
ROlHL-22264-01 Regulation ol contraction in vascular
smooth muscle (dogs)
ROlHL-2255202 Abnormal alveolar permeability and lung
disease (sheep)
ROlHL-22562-02 Mechanism ol cardiac action potential
propagation (tunicates)
** ROlHL-22568-01 pH effect in heart cells-lnlluence ol
cardiac drugs (tissue culture, rats)
R23HL-22575-01 Factors modilying cardiac digoxin eflects
and content (dogs, cats)
ROlHL-22836-01 The spontaneously hypertensive kidney
(rats)
ROlHL-2312801 Cardiac contractility -Ischemia and
hypoxia (rabbits, rats)
ROlHL-23138-01 Myocardial ischemia (dogs. rats, chick
embryo)
** ROlHL-23153-01 Mechanisms of altered CA20 transport in
ischemic heart (dog. rabbit)
ROlHL-23602-01 Physiology of renin, aldosterone and
prostaglandin (human, rats, dogs)
BIOLOGICAL TRANSPORT, ION EXCHANGE AND
TRANSPORT, ION CARRIERS (lONOPHORES)
SEE ALSO ANTIBIOTICS, GRAMICIDIN (UNSPECIFIED)
SEE ALSO ANTIBIOTICS, VALINOMYCIN
POlHL-06308-18 0025 Mechanisms and therapy of
circulatory disease - Subcellular calcium pools in the
genesis of arrhythmias (dogs)
POlHL-06308-18 0039 Mechanisms and therapy of
circulatory disease ■ ANS in regulation of electrophysiology -
Role of Cyclic nulceotides (animals)
ROlHL-10503-13 Cardiac ion transport and ultra structure
(rats, guinea pigs, rabbits)
POIHL-11351-12 0001 Cellular and molecular
mechanisms of myocardial function - Ionic control of
myocardial contractility (animals)
" P01HL-12738-10 0109 Physiologic pharmacology and its
clinical applications ■ Effects of calcium blockers on
skeletal and cardiac muscle (cats)
" P01HL-I2738-10 0110 Physiologic pharmacology and its
clinical applications - Physiology and pharmacology of
arrhythmias (dogs)
POlHL-13262-07 0022 Arterial wall in atherosclerosis -
Mechanisms of platelet prostaglanoin formation
P50HL14153-07 0014 Johns Hopkins Lung Center-
Chronic diseases of airways - Mediator release in asthma
(human)
29
PliOHl 1421/08 0059 Specialized center ol ii<\riir(h in
Ihiombosis Energy metabolism and platelet lunclion
(human)
POIHM49H5 07 001? Adaptation to hypoxia Direct
ellect ol hypoxia un pulmonary vascular smooth muscif
(rats, dogs)
P60HL 15169 05 0018 Support lor center lor sickle cell
disease Studies on sickle cell disease (human, rats,
dogs)
ROIHl 15580 06 Humoral control ol pulmonary and
systemic circulation (animals)
POIHI 15832 06 0012 Chemical structural predispositions
lo lung iniury Contractile structures and conlractilily in
cells ol lung respiratory tract
POIHI 1583506 0021 Study ol muscles related to heart
disease Fast kinetic studies in muscle subcellular
organelles (animals)
POIHI 16117 05 Ion movements and membranes in
cardiovasculai contiol
POIHI 161 1 7 05 0001 Ion movements and membranes in
cardiovascular control Developmental studies of
contractile cell lunctions (rats, rabbits, elasmobranch)
' POIHL 16117 05 0003 Ion movements and membranes in
cardiovascular control Fast kinetic study of calcium
membrane interactions
* POIHL 16117 05 0005 Ion movements and membranes in
cardiovascular control Properties of isolated cell
membranes (rabbits, cats)
' POIHL 16117 05 0007 Ion movements and membranes in
cardiovascular control Physiological and molecular
properties of lonophores (dogs, rabbits)
R01HL-163I8-21 Biochemistry and pharmacology of Na-K
transport
' ROlHL-1647405 Antibiotic-ion interactions (model
membranes)
POIHL 16607 05 0006 Calcium ion and control of
cardiovascular function - Sarcomere and contractile
dynamics of striated muscle cells (animals)
P01H116833 04 0011 Hemoglobin and red cell system in
hemoglobinopathies - Relationship between hemoglobin and
RBC membrane in sickling cells (human, rats)
■ POlHL-16833-04 0016 Hemoglobin and red cell system in
hemoglobinopathies - Calcium-indiced membrane damage
in Hb SS disease (human, animals)
P60HL- 17269-04 0023 National heart and blood vessel
research and demonstration center - Cardiovascular
pharmacology -Ischemia, shock and heart failure (dog cat
rat)
R01HL17516-04 Role of androgen as a risk factor in
atherogenesis (human, animals)
R01HL17853-03 Peripheral circulation in heart failure
(animals)
■ ROlHL-18599-02 Cardiovascular pharmacology of
ionophores (dogs)
' POlHL-18708-03 0005 Oxygen, energy and contractility in
cardiac tissue - Cytosolic calcium homeostasis and
bioenergetics of cardiac tissue (animals)
ROIHL 19044-03 Effect of drugs on development of
cardiac failure (cats)
ROlHL-1922603 Vascular smooth muscle in hypertension
(rats)
' ROIHL-19639-02 Permeability transients of carriers.
channels and heart
ROlHL-20708-02 Voltage clamp of embryonic heart cell
aggregates (rat and chick embryos)
POlHL-20984-02 0001 Cellular mechanisms in cardiac
hypertrophy - Contractile proteins in cardiac hypertrophy
(rabbits, calves)
ROlHL-21 195-02 Innervation of the heart -Acetylcholine
receptors (frogs)
R01HL-2I217-01
platelets
R23HL-2126202 Sodium-calcium interactions in
mammalian myocardium (rabbits, cats)
ROlHL-21367-02 Polyether ionophores -Synthesis of X537A
and analogs
R01HL-218I2 02 Actions of drugs and ions on cardiac
membranes (rabbits, guinea pigs)
ROlHL-21993-01 Hypertensive hypertrophy-Effects of
cardiac mechanics (rats)
ROlHL-22039-02 Ion transport in cardiac muscle (dogs.
rodents, cattle)
ROlHL-22239-01 The molecular basis of electrical
excitability (chick embryos, rats)
R01HL-22354-0I Alpha-adrenergic effects on heart
metabolism (rats)
POlHL-22619-01 0008 Cellular mechanisms of heart
failure - Molecular mechanisms and diflerential contractile
responsiveness in VSM (dogs)
POlHL-2261901 0009 Cellular mechanisms ol heart
lallure - Sarcoplasmic reticulum in cardiac, skeletal and
smooth muscle (rabbits, dogs)
POlHL-22619-01 0010 Cellular mechanisms ol heart
failure - Mitochondria in heart and smooth muscle (rabbits.
rats, dogs)
ROlHL-2277801 Total synthesis of natural cardiotonic
ionophores
ROlHL-22836-01
(rats)
ROlHL-2339201
BIO
ROIHl ?15'r)0l
\fl IptlOII iMl',)
M,i'.l 'rll (iMiiuli-. Miiiiliiii- vir»l
Ion and Shydroxytryptamine transport by
The spontaneously hypertensive kidney
Membrane binding and transport of
BIOLOGICAL TRANSPORT, MEMBRANE MODELS
SEE AISOMIMHKANI, (RriHROCrK GHOS! AND
Ml MKRANE
POIHI 08214 15 U025 Chemii.al and biological piopertiet
of lipids RiosynlhcM', and biological tunctiont ol
plasmalogen (cattle)
PfllHI 08214 15 0040 Chemical and biological properties
111 lipids Nuclear magnetic resonance sludie-, ol lipid'.
*• POIHI 12157 II 0038 functions and mechani'.m-, ol cell
membrane ion tiansport Mc'.hani'.ms and interactions ol
gases and ions with bilayer membranes (human)
" ROIHl 12528 10 NMR relaxation of liquid crystal systems
ROIHl 12760 09 Surtacc studies ol membrane lipids and
proteins
•• P50HI 14147 08 0003 Specialized center of research in
thrombosis Surtace thrombogenicity and phospholipid
vesicle physical properties
P50HI 1414/ 08 0014 Specialized center of research in
thrombosis Theoretical models for electrostatic effects in
blood clot formation
** P50HI 1414/ 08 0015 Specialised center of research In
thrombosis Charge related properties of phospholipid
surfaces in monolayers and vesicles
ROIHL 15648 06 Lipid metabolism Transport by lateral
diffusion (human, rabbit, cattle)
P60HL 16008 06 0018 Wayne State University
comprehensive sickle cell center Hemoglobin S and RBC
membranes Pathogenesis of irreversibly sickled cells
ROIHL 164/4 05 Antibiotic ion interactions (model
membranes)
Human red cell membrane in
Rheology of erythrocyte membrane
Human red cell membrane in
Modehng membrane mechanics and
POIHL 16851 04 0001
health and disease
(human, amphiuma
POIHL- 16851 04 0003
health and disease
blood rheology
ROIHL 1757604 Role of sphingomyelin in biomembranes
and bilaycrs (rats, other mammals)
R01HL-18048-04 Dynamics of artificial and biological
membranes (human)
ROlHL-18255-04 Lipid-protein interactions and calcium
transport (models)
POlHL-18577-03 0003 Lipoproteins -Cell surtacc
interactions Mechanism of lipid exchange in lipoproteins
and cell membranes
ROlHL-19065-02 Molecular oxygen in biological fluids
ROIHL I9I4803 Myocardial organelle lipid structure and
function (dog. rat)
ROlHL-19392-03 Spectroscopic studies of respiratory
metalloproteins
ROlHL-19459-03 Dynamics of atherogenesis and
lipoprotein formation (human, rabbit)
ROlHL-20073-02 Blood compatible materials by fluid
perfusion (human, dogs)
Probes of heart and nerve membranes-
Mechanisms and cellular functions of ion
ROlHL-20254-02
Fluorescent dyes
ROIHL-2072502
transport
** ROlHL-21404-01 Raman spectroscopy of erythrocyte and
model membranes (human)
ROlHL-223 15-01 Intraoperative cardiac oxygen supply
demand (dogs, rabbits, rats)
ROlHL-22562-02 Mechanism of cardiac action potential
propagation (tunicates)
ROlHL-22771-01 Thrombogenic phospholipid surfaces
(cattle)
** ROIHL-23183-01 Voltage dependent conductance in
membranes
BIOLOGICAL TRANSPORT, MEMBRANE
PERMEABILITY AND TRANSPORT
SEE ALSO CARDIOVASCULAR SYSTEM, ENDOTHELIUM
PERMEABILITY
SEE ALSO CEREBROVASCULAR SYSTEM. BLOOD-BRAIN
BARRIER
SEE ALSO CEREBROVASCULAR SYSTEM. BLOOD-
CEREBROSPINAL FLUID BARRIER
SEE ALSO GASTROINTESTINAL FUNCTION ABSORPTION-
TRANSPORT (GENERAL)
SEE ALSO KIDNEY FUNCTION, GLOMERUUR FILTRATION
SEE ALSO KIDNEY FUNCTION, RENAL TUBULAR TRANSPORT
SEE ALSO MEMBRANE. MEMBRANE (BIOLOGICAL) STRUCTURE
SEE ALSO METABOLIC DISORDERS INBORN TRANSPORT
DISORDERS
SEE ALSO PREGNANCY CIRCULATION, PUCENTAL TRANSFER
SEE ALSO RESPIRATORY FUNCTION PULMONARY DIFFUSION
SEE ALSO SKIN ABSORPTION
" ROlHL-00082-30
frogs, rats)
ROlHL-02334-23
Transmembrane movements (barnacles,
Micropuncture study of kidney function
calcium and potassium ionophores
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level
Oriented significantly to above subject.
(rats, animals)
R01HL04457-20 Cellular aspects of active transport (fish,
rabbits, anurans. turtles)
POlHL-06285-18 0195 Cardiovascular-respiratory
physiology and biochemistry - Thyroid thermo genesis and
sodium transport (rats)
POlHL-06285-18 0196 Cardiovascular-respiratory
physiology and biochemistry • Hormonal regulation of
sodium transport -Epithelial cell membranes (toads)
Icontd)
M Grant has subproiects describing specific research aspects
See Appendix for investigator's name and grant number
BIO
POlHL-06285-18 0197 Cardiovascularrespiratoty
physiology and biochemistry - Microperfusion and
micropuncture of renal tubules (hamsters, desert rats)
*• P01HL06285-18 0198 Cardiovascular-respiratory
physiology and biochemistry - Renal tubular secretion of
hydrogen ion (animals)
POlHL-06285-18 0200 Cardiovascular-respiratory
physiology and biochemistry - Medullary counter-current
system (animals)
** POlHL-06285-18 0203 Cardiovascular-respiratory
physiology and biochemistry - Pathways of lipid transport
in the blood (animals)
** POlHL-06285-18 0204 Cardiovascular-respiratory
physiology and biochemistry - Lipoprotein lipase and
triglyceride transport in chylomicrons (guinea pig, rat)
POlHL-06285-18 0211 Cardiovascular-respirator>
physiology and biochemistry • Purple membrane of
Halobacteria
POlHL-06285-18 0212 Cardiovascular-respiratory
physiology and biochemistry - Membrane structure and
function-Gap junction (bovine)
POlHL-0631417 0054 Immunologic mechanisms in
cardiovascular disease ■ Physiology of cell communications
(mice, frogs, guinea pigs)
POlHL-06664-17 Cardiopulmonary function in remediable
vascular disease
POlHL-0666417 0036 Cardiopulmonary function in
remediable vascular disease - In vitro studies on the
mechanism of ischemic damage to cells (rabbits)
** P01HL06664-17 0038 Cardiopulmonary function in
remediable vascular disease - The dynamics of ADH-
stimulated osmotic water flow
** POlHL-06664-17 0040 Cardiopulmonary function in
remediable vascular disease - The coupling of ion transport
to metabolism (toads)
Regulation of ventilation and
Electron microscope core research
M
POlHL-08805-15 0042
pulmonary circulation
laboratory
POlHL-08805-15 0048
pulmonary circulation
Regulation of ventilation and
Permeability of alveolo -Capillary
membrane in normal pulmonary hypertensive lung
R01HL0889314 Structure and function of membrane
proteins (human)
POlHL-0889914 0073 Tolerance to respiratory gases in
health and disease - Biophysical mechanisms Involved in
isobaric gas counterdiffusion syndrome
ROlHL-08977-14 Quantitation of flow and solute flux in
microvessels (cats, rats)
R01HL0912514 Ultrastructural cytochemistry (human,
chick)
ROlHL'09364-14 Ion transport by heart mitochondria
(cattle, rat, rabbit)
ROlHL-09610-14 Control of cholesterol metabolism-Bile
acid transport
ROlHL-09906-13 Membrane transport processes in red
blood cells
ROlHL-09906-13 0021 Membrane transport processes In
red blood cells - Membrane potentials in human red blood
cells due to proton gradients
ROlHL-09906-13 0022 Membrane transport processes in
red blood cells - Anion transport in dog and cat red cells
ROlHL-0990613 0024 Membrane transport processes in
red blood cells - Inhibition of sulfate transport in human
RBCs by isothiocyanic acid esters
ROlHL-10503-13 Cardiac ion transport and ultrastructure
(rats, guinea pigs, rabbits)
ROIHL-10940-13 Lipid transport (rabbits, cattle, chickens)
ROlHL-1 II 53-12 Quantitation of flow and solute flux in
microvessels (cats, rats)
P01HL-11310-12 0102 Mechanisms of cardiovascular
disease - Cardiac membrane and ion mobility (dogs)
ROlHL-1 1901-12 0017 Effects of metabolic surgery on
the hyperlipidemias - Membrane permeability, blood
viscosity, oxygen uptake-Rheology studies (rabbits)
POlHL-12157-11 0033 Functions and mechanisms of cell
membrane ion transport - Immunology aspects of active
Na-K transport in sheep red cell (also human, mice)
P01HL12157-11 0056 Functions and mechanisms of cell
membrane ion transport - Isotopic fluxes in synthetic
strands of heart cells (chick embryo)
POlHL-12157-11 0057 Functions and mechanisms of cell
membrane ion transport - Electrophysiological
investigations of synthetic strands of heart muscles (rats)
POlHL-12157-11 0058 Functions and mechanisms of cell
membrane ion transport - Ionic and osmotic regulation in
toadfish-A euryhaline aglomerular teleost
ROlHL-12528-10 NMR relaxation of liquid crystal systems
POlHL-12738-10 0044 Physiologic pharmacology and its
clinical applications - Cardioactive drugs and
electrophysiological properties of cardiac cells (sheep)
POlHL-1273810 0110 Physiologic pharmacology and its
clinical applications - Physiology and pharmacology of
arrhythmias (dogs)
ROlHL-12839-09 Flow, transport and membrane
phenomena in blood (human)
ROlHL-12879-09 0002 Pulmonary transport and
metabolism in vivo - Osmotic compartmental model of
barrier exchange
ROlHL-12879-09 0011
metabolism in vivo -
cells (human, animals)
Pulmonary transport and
Membrane characteristics of lung
30
ROlHL-12974-10 Tracer kinetics, flows and masses in
body organs (human, dogs)
ROlHL-13028-09 Regulation of myocardial fatty acid
metabolism (rats)
ROlHL-13029-09 Metabolic regulation of sugar transport
(pigeons, rats)
ROlHL-13172-10 Post-trauma lung mechanics and fluid
exchange (human, dogs, monkeys)
ROlHL-1323709 Erythrocytes during early development
(human, animals)
ROlHL-13256-08 Amino acid transport by red cell
membranes (pigeons)
ROlHL-13306-08 Pharmacological control of cardiac
membrane currents (cattle, rabbits)
ROlHL-13339-08 Pharmacology of developing cardiac
tissues (chick embryo)
R01HL13596-07 Clearance of plasma proteins from
alveoli
ROlHL-13645-11 Tryptophan-induced pulmonary
emphysema (cattle, goats, rabbits)
R01HL-14092-07 Homeostatic regulation of plasma choline
(rats, dogs, chickens)
P50HL-14230-07 0092 A/S SCOR-Lipids. atherosclerosis
and thrombosis - Tissue lipids -Cell culture studies
(human)
POlHL-1438807 0191 Regulation of the circulation in
pathological states - Regulation of chloride transport in
epithelial membranes (turtles)
POlHL-14388-07 0192 Regulation of the circulation in
pathological states - Renal tubular secretion of magnesium
(rats)
POlHL-144 14-07 0014 Environmental influences on
cardiorespiratory and cellular functions - Temperature and
acid-base status in tissues, cells, and subcellular system
POlHL-144 14-07 0016 Environmental influences on
cardiorespiratory and cellular functions - Effects of
pressure on membrane and cellular function (human.
rabbits)
ROlHL-14483-08 Energy conservation in heart
mitochondria (cattle, E coli, human)
ROlHL-14781-08 Lipid deposition in mammalian cells
(mice)
ROlHL-14820'07 Factors affecting physiology of biological
membranes (human)
ROlHL-14854-07 Lung and tissue mechanics (monkeys,
dogs)
P60HL-1515707 0011 Comprehensive center for sickle
cell disease - Development of specific anti-sickling
compound (human)
P60HL-151 57-07 0018 Comprehensive center for sickle
cell disease - Red blood cell membrane physiology in sickle
cell anemia (human)
P60HL-15162-07 0017 Comprehensive sickle cell center -
Hemoglobin, erythrocytes and sickle cell anemia (human,
rabbit)
P60HL-1516207 0020 Comprehensive sickle cell center -
Biophysical studies of normal and sickle red cells (human)
ROlHL-15504'05 Animal model for studies on averting
atherosclerosis (swine)
ROlHL-15622-05 Computer simulation in cardiology (rats,
dogs)
ROlHL-15793-06 Molecular aspects of erythrocyte
membrane resealing (human)
POlHL-15835-06 0021 Study of muscles related to heart
disease - Fast kinetic studies in muscle subcellular
organelles (animals)
P60HL- 15999-05 0014 Miami comprehensive sickle cell
center - Biochemical and morphological parameters of
sickle cells (human)
P60HL-16008-06 0018 Wayne State University
comprehensive sickle cell center - Hemoglobin S and RBC
membranes -Pathogenesis of irreversibly sickled cells
R01HL16093-05 Functional properties of hemoglobin and
erythrocytes
POlHL-161 17-05 0007 Ion movements and membranes in
cardiovascular control - Physiological and molecular
properties of ionophores (dogs, rabbits)
ROlHL-16328-06 Membrane electrical properties of
vascular muscle (human, animals)
ROlHL-1647405 Antibiotic-ion interactions (model
membranes)
ROIHL-165 12-04 Lipoprotein metabolism and hormonal
regulation (chickens)
ROlHL-16582-05 Artificial lungs (dogs)
POlHL-16607-05 0001 Calcium ion and control of
cardiovascular function - Bilayer lipid membranes,
antibiotic probes, and SR function
P01HL16607-05 0005 Calcium ion and control of
cardiovascular function - Chemical modifications of the
sarcoplasmic reticulum membranes (rabbits)
ROlHL-16660-06 Phospholipid-cholesterol and
phospholipid-protein interactions
ROlHL-16674-05 Airborne metals and lung permeability
(bullfrogs, rats)
ROlHL-167 11-05 RBC and endothelial membrane material
characteristics (human)
ROlHL-16746-04 Design of ion-selective molecules
POlHL-16833-04 0008 Hemoglobin and red cell system in
hemoglobinopathies - Membrane associated phenomena in
SS disease
BIO
POlHL-16833-04 0016 Hemoglobin and red cell system in
hemoglobinopathies Calcium-indiced membrane damage
in Hb SS disease (human, animals)
POIHL- 16833-04 0017
hemoglobinopathies
effect (human)
POlHL-1685104 0006
health and disease
Hemoglobin and red cell system in
Sulfhydryl group blockade antisickling
Human red cell membrane in
Hexose transport and erythrocyte
membrane proteins (human)
P60HL- 17269-04 0022 National heart and blood vessel
research and demonstration center - Medicinal chemistry
(rabbit, dog, guinea pig)
P60HL- 17269-04 0045 National heart and blood vessel
research and demonstration center - Regulation of
lipogenesis in hyperlipoproteinemia (human, tissue culture)
ROlHL-17411-04 Molecular studies of red blood cell
spectrin (human)
ROlHL-1745204 Depolarization induced cardiac
automaticity (human, animals)
ROlHL-17571 03 Study of membrane permeability by NMR
relaxation (human)
ROIHL 17576-04 Role of sphingomyelin in biomembranes
and bilayers (rats, other mammals)
ROlHL-17596-03 Leukocyteendothelial interactions (rats)
P50HL- 17648-04 0014 Study of ischemic heart disease -
Antidysrhythmic drugs and mammalian cardiac Purkinje
fibers (sheep, dog)
P50HL 17669-04 0022 Ischemic heart disease center
(SCOR) Pathological studies of human and experimental
ischemic heart disease
ROlHL-1 7882-04 Regulation of HMG-COA reductase and
sterol synthesis (human, mammals)
Mammalian renal microcirculation
Limiting factors in oxygen uptake in the
Regulatory mechanisms in blood
'Excludes routine nethodology OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
R01HL17902-04
(hamsters)
R01HL17967-04
lung
ROlHL-17998-04
circulation (dogs)
ROlHL-18022'03 Role of multicomponent diffusion in gas
exchange (avian eggs)
ROlHL-18028'03 Absorption of nonvolatile compounds
from the lung
R01HL18038-03 Structure and function of heart
mitochondria (cattle)
ROlHL-18048-04 Dynamics of artificial and biological
membranes (human)
ROlHL-18053-03 Intracellular Ionic activities in heart
muscle (frogs)
ROlHL-1806802 Chemistry and activity of homologous
heparin fractions (rodents)
ROlHL-18148-04 Adrenal catecholamine secretion
ROIHL- 18206-04 Regulation of metabolism in oxygen
deficient hearts (rats)
ROlHL-18226-04 Mechanism of oxygen supply to tissue
(human, animals)
ROlHL-18255-04 Lipidprotein Interactions and calcium
transport (models)
ROlHL-18292-04 Vasodilation and microvascular oxygen
delivery (dog. hamster)
ROlHL-18599-02 Cardiovascular pharmacology of
ionophores (dogs)
ROlHL-18647-03 Ischemic myocardial injury in cultured
heart cells (rats)
ROlHL-18660-03 Neurotransmitter receptors in human
erythrocytes
R01HL18798-04 0001 Nervous and ionic factors in
sudden cardiac death - Potassium loss during myocardial
ischemia (rabbits)
ROlHL-18818-04 Stereochemical mechanism of sickling of
hemoglobin S (human)
P01HL18827-02 0001 Platelet vessel wall interactions in
thrombogenesis - Role of endothelial cells in the production
of thrombi (human, cattle)
ROlHL-19000-03 Irreversible myocardial injury (rats)
ROlHL-19068-03 Changes in membrane properties during
erythropoiesis (chick embryo)
ROlHL-19082-01 Hypoxia-induced relaxation of vascular
smooth muscle
ROlHL-19148-03 Myocardial organelle lipid structure and
function (dog, rat)
P50HL19 153-02 0004 SCOR -Pulmonary edemas-Eitology,
pathogenesis - Physical mechanisms in lung transvascular
transport-Math models (sheep)
P50HL-19153-02 0005 SCOR -Pulmonary edemas-Eitology.
pathogenesis - Lung vascular permeability measured by
indicator dilution methods (sheep)
POlHL-19242-02 0002 Study of vascular smooth muscle ■
Vascular smooth muscle response to serum lipoproteins
(rats)
ROlHL-19315-03 Study of glomerular permeability (fish,
turtle, frog, chordates, Crustacea)
R01HL1939902 Atherosclerosis-Early events and
regression factors (rats)
ROlHL-19463-02 Pathophysiology of acute renal failure
(rats)
ROlHL-19639-02 Permeability transients of carriers.
channels and heart
ROlHL-1967303 Surgical aspects of shock and hypoxia
(dogs, monkeys, rats)
ROlHL-19733'03 Absorption of antigen through inflamed
lungs (rabbits)
(contd)
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
BIO
POIHI 1973/0? 0004 Cdlulti ind molrculac aspocU ol
ttspiiitory phyiiok)|y Rapid taaclions and eiYlhtocyta
•>chan|ts ol blood duiini taspiialory tianspoil
POIHI 19737 0? 0008 Cellular and moleculai asptcts ol
r«spi[ato(> physiology Kinatics ol movamant ol acid
matabolitas Icom call to capillani blood (do|s)
ROIHI 20061 02 Saium lipoproteins and cell cholesterol
metabolism (rats, human)
ROIHI 20070 02 Alpha 1 anlitrypsm deliciency (human
hamsters)
ROIHI 20073 02 Blood compatible materials by fluid
perlusion (human, dogs)
R01H12015302 Intracellular pH and myocardial
electropharmacology (dogs, guinea pigs)
' ROIHI 20177 02 Etiects ol erythrocyte detormability on
tissue perlusion (rats)
ROIHL 2023002 Analysis ol the action potential ol
cardiac muscle (sheep)
ROIHL 20254 02 Probes ol heart and nerve membranes
Fluorescent dyes
ROIHI 20283 02 Maintenance ol cellular integrity in
ischemic hearts (cats)
* ROIHL 20303 03 Cholesterol distribution in erythrocyte
membrane (human, animals)
* ROIHL 20308 02 Regulation ol myocardial acylcarniline
transport (rats)
ROIHL 20366 03 Protein turnover and ammo acid
transport by lung (rats)
ROlHL-20544 02 Integrated regulation o( myocardial
energy metabolism (rats, guinea pigs)
* POIHL 20592 02 0013 Cell biology ol cardiac and
skeletal muscle Sarcoplasmic reticulum in skinned
muscle cells (Irogs)
* ROIHL 20708-02 Voltage clamp ol embryonic heart cell
aggregates (rat and chick embryos)
R01HL20711 01 Structure-function relationships in red
cell NA-K pumps (goats)
ROlHL-20720-02 Myocardial protection during
cardiopulmonary bypass (dogs)
ROIHL 2072502 Mechanisms and cellular functions of ion
transport
ROIHL 20859-02 Beta adrenergic catecholamine receptor
ROlHL-2088202 Interactions of plasma lipoproteins with
erythrocytes (Rhesus, human)
'* P60HL-20985-01 0004 Northern California sickle cell
center ■ Characterization of irreversibly sickled cells
(human)
P60HL-2098501 0006 Northern California sickle cell
center - Antisickling properties ol imidoesters (human, rats)
POlHL-2099402 0007 Dynamics of neutrophil elastase in
the lung ■ The etiology of experimental emphysema (dogs)
ROlHL-21009-02 Effects of air pollutants on lung cells in
culture (rats)
ROlHL-21014-01 Mechanism of the inotropic action of
cardiac glycosides
POlHL-2 1016-02 0008 Sickle cell anemia and other
hemoglobinopathies ■ The clinical variations of sickle cell
anemia
ROlHL-2 103801 Electrically induced cardiac EM-
histochemical changes (animals)
R23HL-2 105002 Mechanisms of re-expansion pulmonary
edema (rabbits)
ROlHL-21076-02 Lung fluid, protein exchange after
hemorrhagic shock (sheep)
ROlHL-2 1099-02 Subcellular changes of blood vessels in
hypertension (rats)
ROlHL-2 113602 Ion activities and transport in cardiac
muscle cells (sheep)
R23HL-2 11 50-02 Regulation of airway mucous glands and
ion transport (dogs, ascaris)
ROlHL-21179-01 Volume regulation-Role of the membrane
potential (amphiuma)
ROlHL-21195-02 Innervation of the heart-Acetylcholine
receptors (frogs)
R23HL-2121301 A model for calcium homeostasis in
excitable tissue (marine worms)
** ROlHL-21217-01 Ion and 5-hydroxytryptamine transport &/
platelets
ROlHL-2129402 Voltage clamp of isolated cardiac
Purkinje cells (dogs)
** ROlHL-2 1376-02 Blood-gas barrier solute and water
transport (rabbits)
** ROlHL-2146901 Active transport and effect of CAOO in
sickle cell (human)
ROlHL-21525-02 Effect of cations, anions and water upon
blood vessels (dogs, rats)
ROlHL-2157001 Antiarrhythmic studies on 2-substituted
aminoindenes (dogs)
ROlHL-21812-02 Actions of drugs and ions on cardiac
membranes (rabbits, guinea pigs)
** ROlHL-2184501 Human red cell membrane -Structure and
function
•* ROlHL-21849-02 Control of sodium transport and cellular
respiration (toad bladder)
R01HL-22039-02 Ion transport in cardiac muscle (dogs.
rodents, cattle)
ROlHL-22101-02 Hormone-substrate interaction in diabetic
myocyte (dogs, rats)
** ROlHL-22135-01 Control of calcium fluxes across cardiac
membranes (dogs, rabbits, guinea pigs)
ROlHL-22177-02 Mechanisms of control of pulmonary
smooth muscle (dogs)
ai
ROlHt 22231 02 Modulillon ol calcium control ol cirdlic
myolibrili (rats)
ROIHL 22264 01 Regulation ol contriclion in vascular
smooth muscle (dogs)
ROIHL 22281 01 Microprobe analysis and metabolite
levels ol ischemic mycardium (dogs)
ROIHL 22327 01
skin (swine)
ROIHI 22502 01
platelet secretion
ROIHL 22549 02
membrane (dogs)
ROIHL 22552 02
disease (sheep)
ROIHL 22562 02
Transport ol arterial blood giMl through
Role ol phospholnositides in human
Transport scioss alveolar capillary
Abnormal alveolar permeabrlity and lung
Mechanism of cardiac action potential
propagation (tunicates)
ROIHL 22568 01 pH effect in heart cells Influence of
cardiac drugs (tissue culture, rats)
*• ROIHL 22569 02 Intestinal secretion -Capillary and tissue
forces (dogs, cats)
R23HL 22575 01 Factors modilying cardiac digoxin effects
and content (dogs, cats)
ROIHL 2288301 Lung epithelial cell interactions in vitro
** ROIHL 22924 01 The airway mucosal barrier (guinea pigs)
** R01HL22981 17 Membrane associated functions in
microorganisms (bacteria, protozoa)
ROlHL-23015-01 Mechanisms of hypo^incotic pulmonary
edema (human, dogs)
R01HL2313801 Myocardial ischemia (dogs. rats, chick
embryo)
ROIHL 23142 01 Mechanisms of membrane injury in
myocardial ischemia (dog)
ROIHL 23153-01 Mechanisms of altered CA20 transport in
ischemic heart (dog. rabbit)
ROlHL-23166-01 Pathology of mitochondria in ischemic
myocardium (rats, cattle)
** ROlHL-23183-01 Voltage dependent conductance in
membranes
ROIHL 23210 01 Biology ol normal and hypertrophied
pulmonary vessels (cat. human)
** ROlHL-23392-01 Membrane binding and transport of
calcium and potassium ionophores
BIOLOGICAL TRANSPORT, PASSIVE TRANSPORT
POlHL-06285-18 0199 Cardiovascular-respiratory
physiology and biochemistry - Renal tubular reabsorption of
sodium chloride (hamsters, rabbits)
POlHL-06308-18 0035 Mechanisms and therapy of
circulatory disease ■ Mechanisms for electrophysiological
changes in myocardial infarction (dogs)
ROIHL 1283909 Flow, transport and membrane
phenomena in blood (human)
ROlHL-13029-09 Metabolic regulation of sugar transport
(pigeons, rats)
P01HL1438807 0192 Regulation of the circulation in
pathological states - Renal tubular secretion of magnesium
(rats)
ROlHL-20725-02 Mechanisms and cellular functions of ion
transport
P60HL-20985-01 0004 Northern California sickle cell
center - Characterization of irreversibly sickled cells
(human)
R23HL-21213-01 A model tor calcium homeostasis in
excitable tissue (marine worms)
ROlHL-22135-01 Control of calcium fluxes across cardiac
membranes (dogs, rabbits, guinea pigs)
BIOLOGICAL TRANSPORT, PASSIVE TRANSPORT,
DIFFUSION
R01HL08977-14 Quantitation of flow and solute flux in
microvessels (cats, rats)
ROlHL-12760-09 Surface studies of membrane lipids and
proteins
P01HL14388-07 0191 Regulation of the circulation in
pathological states Regulation of chloride transport in
epithelial membranes (turtles)
** ROlHL-15648-06 Lipid metabolism -Transport by lateral
diffusion (human, rabbit, cattle)
** ROlHL-18004-02 Transport through arterial wall-
Biophysical aspects (rabbits)
ROlHL-18736-03 Protein transport through arterial tissue
(rabbits)
** R01HL19008-02 Carbon dioxide diffusion in lung and
muscle tissues (dogs)
ROlHL-19065-02 Molecular oxygen in biological fluids
ROlHL-1945402 Rheological factors in transport across
arterial wall (dogs)
" R01HL1949103 Mechanism of iron storage and
mobilization by ferritin (horse)
ROlHL-22235-01 Mechanism of cardiac pacemaking
(rabbits)
ROlHL-22843-01 Pulmonary physiology in liquid ventilation
(lambs)
BIOLOGICAL TRANSPORT, PASSIVE TRANSPORT,
OSMOSIS
SEE ALSO BODY FLUID BALANCE, OSMOTIC PRESSURE
SEE ALSO CELL FLUIDS. OSMOTIC PRESSURE
R01HL0990613 0019 Membrane transport processes in
red blood cells - Hemoglobin change and membrane
potentials in red blood cells at varying volumes
BIO
POIHI 143««0; 0183 Regulalion ol the circulation m
pgtholugiial ililej Vawprtsun in cardiovascular
regulalion (dogs, rils)
ROIHI 19320 03 Angiotensin neurophi(macolO|y
Relationship to sodium
ROIHI 211/901 Volume regulation Role ol the membrane
potential (amphiuma)
BIOLOGICAL TRANSPORT, SECRETORY
MECHANISMS
Structural aspects ol lung turlaclant
Micropuncluie study of kidney lunction
ROlHlOl/70 26
system (rats)
ROIHL 02334 23
(rats, animals)
ROIHL 02/51 21 function and metabolism ol serum
albumin (mammals, fish, amphibians)
POIHL 031/4 23 0009 Mechanisms ol acute vascular
reaction to injury Mast cell Irpid interaction (human, rats)
ROIHL 03181 21 002/ Hemodynamics as applied lo
surgical problems Hemodynamic studies ol the Gl tract
(dogs)
P01HL06285 18 0189 Cardiovascular respiratory
physiology and biochemistry Mucociliary clearance (c»t»,
dogs)
POIHL 06285 18 0198 Cardiovascular respiratory
physiology and biochemistry Renal tubular secretion ol
hydrogen ion (animals)
POIHL 06285 18 0200 Cardiovascular respiratory
physiology and biochemistry Medullary counter current
system (animals)
POIHL 06835 1/ 0038 Cardiovascular disease Effect ol
chronic administration of angiotensin antagonist (rats)
P01HL06835 17 0056 Cardiovascular disease
Angiotensin analogs Sarcosine on arterial pressure,
aldosterone (dogs)
POIHL 08682-15 0027 Regulation of the cardiovascular
system Cardiac mechanoreceptors Reflex regulation ol
renal function (dogs)
P01HL09011 15 0015 A research and resource program
in blood - Regulation of synthesis and transport of diverse
proteins in liver (rats)
ROlHL-0992113 Mechanisms related to congestive heart
failure (dogs, human, rat)
* ROIHL 1061213 0020 Humoral factors in heart failure
and hypertension - The control of renin release in the dog
* ROlHL-10612-13 0021 Humoral factors in heart failure
and hypertension - The control of aldosterone secretion
(dogs)
POlHL-1167811 0046 Cardiovascular dynamics and their
control - Regulation of aldosterone secretion and related
factors (dogs)
POlHL-1167811 0047 Cardiovascular dynamics and their
control - Unidentified pituitary factor in regulation of
aldosterone secretion (rats)
* POlHL-1167811 0066 Cardiovascular dynamics and their
control - Closed-loop analysis of the aldosterone control
system (dogs)
ROIHLI 1901-12 0014 Effects of metabolic surgery on
the hyperlipidemias - Effect of bypass on gastrin levels
(dogs, human)
ROlHL-12650-08 Environmental pathobiology of the lung
(hamsters, rats)
* ROlHL-12990-09 Control of antidiuretic hormone secretion
and metabolism (dogs. rats, rabbits)
ROlHL-1340509 Regulation of lipid metabolism in the
lung (rats)
ROlHL-13885-08 0009 Cystic fibrosis and pulmonary
disease - Respiratory mucus glycoproteins (human, rabbits)
■* ROlHL-13917-20 Secretion and effects of adrenal
hormones (human, rabbits, sheep)
P50HL1414708 0018 Specialized center of research in
thrombosis • Biochemical aspects of platelet function in
thrombosis and cell growth (human)
P50HL142 14-07 0021 Newborn lung center for hyaline
membrane disease - Development of surfactant system-
Surfactant production and release (rat. rabbit)
P50HL-14214-07 0022 Newborn lung center for hyaline
membrane disease • Functional integrity of surfactant
system-Hyaline membrane disease (lamb, rat)
P50HL-14217-08 0059 Specialized center of research in
thrombosis • Energy metabolism and platelet function
(human)
P50HL-14237-07 0004 Support for arteriosclerosis center
- Synthesis, secretion of normal, abnormal plasma
lipoproteins (rodents, monkeys)
POlHL-14388-07 0179 Regulation of the circulation in
pathological states - Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
** POlHL-14388-07 0192 Regulation of the circulation in
pathological states • Renal tubular secretion of magnesium
(rats)
ROlHL-15307-06 Central nervous control of renin and
blood pressure (dogs)
ROlHL-15427-06 Secretion of plasma lipoproteins (rats)
P01HL15832-06 9001 Chemical-structural predispositions
to lung injury • Tissue culture studies of lung cell function-
Core facility
POlHL-16137-05 0008 Alveolar biology • Macromolecular
events in pulmonary cells in toxic environments (animals)
ROlHL-16714-05 Endothelial cell communication in
homeostasis (human, mammals)
** ROlHL-16730-03 Physiology of mucociliary transport (rats,
frogs, rabbits)
(contd)
'Excludes routine methodotogy OR covers only general projects whlcti preclude
**0riented significantly to above subject.
indexing at the specific level.
M Grant has subprojeds descnbing specific research aspects
See Appendix for investigator's name and grant number.
The endocrine kidney in hypertension
Human alphalantitrypsin synthesis in
Cyclic nucleotides and calcium in
BIO
ROIHL-18019-04
(mice)
** R01HL18148-04 Adrenal catecholamine secretion
ROlHL-18181-04 Surfactant metabolism-Alveolar cells and
lung disease (mice, rabbits)
R01HL18340-04 Electron microscopy of the
juxtaglomerular apparatus (rats)
POlHL-18575-03 0005 Mechanisms of vascular changes
m hypertension - Renin synthesis in normotensive and
hypertensive pigs (also rats, dogs)
ROlHL-18601-01 Regulation of neurotransmitter release by
adenosine (tats)
ROlHL-18876-03
vitro
** R01HL18937-03
platelets (human)
ROIHL 1899504 Cardiovascular determinants of
catecholamine release (dogs)
P50HL-19157-02 0003 Studies in cystic fibrosis and
bronchiolitis - Nasal mucosal function in patients with
cystic fibrosis
** P50HL-19I57-02 0004 Studies in cystic fibrosis and
bronchiolitis - Macromolecular regulators of mucus
secretion-Invertebrate model
P50HL-19157-02 0007 Studies in cystic fibrosis and
bronchiolitis - Analysis of cystic fibrosis factors (human)
M P50HL-19160-02 Mucus abnormality in cystic fibrosis
** P50HL-19160-02 0001 Mucus abnormality in cystic
fibrosis • Regulation of respiratory secretions (rat. human)
** P50HL-19160-02 0002 Mucus abnormality in cystic
fibrosis • Ultrastructure. cytochemistry of pulmonary
secretion (human, rat)
R01HL1916803 Biosynthesis of plasma lipoprotein (rats,
rabbits)
** P50HL-19185-02 0001 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Sites of synthesis,
secretion and structure of surface active material (rat)
** P50HL-19185-02 0003 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Factors affecting formation
and release of pulmonary surfactant in fetal lambs
P50HL-19187-02 0004 Pediatric pulmonary SCOR-Hyaline
membrane disease • Hyaline membrane disease -Surface
active material, lamellar bodies (mice, rats)
ROlHL-1972103 Lung inflammation-Lysosomal proteases
and liposomes (human, rabbits)
** ROlHL-20278-02 Cellular mechanisms of renin secretion
(rats)
** ROlHL-20366-03 Protein turnover and amino acid
transport by lung (rats)
ROlHL-2086802 Regulation of glycoprotein biosynthesis in
lung (swine)
P50HL-21006-02 0003 Specialized center of research in
arteriosclerosis ■ Transport of vitamin A in plasma (human,
rat)
R23HL-2115002 Regulation of airway mucous glands and
ion transport (dogs, ascaris)
R23HL-21369-02 Tracheal mucin synthesis in experimental
bronchitis (rats)
R23HL-21413-02 Structure and function of platelet
calcium-binding protein (human)
ROlHL-2175611 Vascular disease-Cytochemistry and
ultrastructure (human, rats. mice, hamsters)
ROlHL-21996-01 Alteration of digitalis and aldosterone
disposition (rats, rabbits, mice, dogs)
ROlHL-22051-01 Role of angiotensin II in vasopressin
release (human)
** ROlHL-22333-01
(rats)
** ROlHL-2244401
culture (human)
" ROlHL-22502-01
platelet secretion
ROlHL-22561-01
circulation (cats)
ROlHL-22569-02
forces (dogs, cats)
** POlHL-22633-01 0001 Cellular and molecular biology of
lipoprotein metabolism - Secretion of lipoproteins by the
perfused liver (rats, rabbits)
'* R23HL-22728-01 Neural control of renin secretion (dogs)
Regulation of hepatic production of HOL
Role of angiotensin
Cellular basis of small airways function
Bronchial mucus production in organ
Role of phosphoinositides in human
Hormonal control of mesenteric
Intestinal secretion -Capillary and tissue
ROIHL-22812-01
(rats)
ROlHL-22883-01
ROlHL-23593-01
secretion (rats)
Lung epithelial cell interactions in vitro
Mast cell granules-Structure and
BIOLOGICAL TRANSPORT, SECRETORY
MECHANISMS, EXCRETION
P50HL-14164-07 0037 A/S SCOR -Comparative and
experimental atherosclerosis - Genetic control of plasma
cholesterol -Interaction of dietary fatty acid (monkey)
POlHL-14388-07 0225 Regulation of the circulation in
pathological states - Release of renal prostaglandins by
saluretic-diuretic agents (dogs)
ROlHL-14720-08 Factors governing the renal excretion of
acid (humans, rats)
ROlHL-14844-06 Mucous glycoprotein in human respiratory
epithelium (also wheat)
ROlHL-19008-02 Carbon dioxide diffusion in lung and
muscle tissues (dogs)
ROlHL-19366-03 Renal Starling forces in experimental
conditions (rats, rabbits)
32
BIOLOGICAL TRANSPORT, TRANSPORT
EFFECTORS
SEE ALSO BIOLOGICAL TRANSPORT, ION EXCHANGE AND
TRANSPORT, ION CARRIERS (lONOPHORES)
SEE ALSO BIOLOGICAL TRANSPORT, TRANSPORT PROTEINS
(SEE ALSO SPECIFICS)
" POlHL-063 12-17 0034 Surgical cardiology - Metabolic
factors in cardiac function -Creatine phosphate depletion
(animals)
ROIHL 13029-09 Metabolic regulation of sugar transport
(pigeons, rats)
POlHL-14388-07 0191 Regulation of the circulation In
pathological states - Regulation of chloride transport in
epithelial membranes (turtles)
ROlHL-16454-03 Vascular muscle reactivity in
hypertension (human, rats)
ROlHL-17452-04 Depolarization induced cardiac
automaticity (human, animals)
ROlHL-18003-05 Digitalis -Mechanism and reversal studies
(dog, sheep, duck, guinea pig, human)
ROlHL-19733-03
lungs (rabbits)
** ROlHL-20308-02
Absorption of antigen through inflamed
Regulation of myocardial acylcarnitlne
transport (rats)
ROlHL-207 11-01 Structure-function relationships in red
cell NA-K pumps (goats)
ROlHL-22444-01 Bronchial mucus production in organ
culture (human)
R01HL-22568-01 pH effect in heart cells -Influence of
cardiac drugs (tissue culture, rats)
R23HL-22882-01 Modulation by disease of effect of
furosemide in man
ROlHL-23161-01 0002 Biology of myocardial ischemia -
Palmitylcarnitine inhibition of ion pumps in myocardial
ischemia (dog, sheep)
BIOLOGICAL TRANSPORT, TRANSPORT
ENERGETICS
ROlHL-13029-09 Metabolic regulation of sugar transport
(pigeons, rats)
P50HL-142 12-07 0013 Correlated studies of pulmonary
fibrosis - Mechanism of beryllium pathogenicity in the lung
(human, rabbit, guinea pig)
** ROlHL-14483-08 Energy conservation in heart
mitochondria (cattle, E coli, human)
ROlHL-15622-05 Computer simulation in cardiology (rats,
dogs)
ROlHL-158 13-05 Cardiac anoxia -Protective effect of
carbohydrate (dogs)
ROlHL-17729-04
(human)
ROlHL-20308-02
Stimulus-response coupling in platelets
Regulation of myocardial acylcarnitlne
transport (rats)
R0IHL-22135-0I Control of calcium fluxes across cardiac
membranes (dogs, rabbits, guinea pigs)
ROlHL-23138-01 Myocardial ischemia (dogs, rats, chick
embryo)
BIOLOGICAL TRANSPORT, TRANSPORT
PROTEINS (SEE ALSO SPECIFICS)
SEE ALSO ENDOCRINOLOGY, HORMONE BINDING PROTEINS
SEE ALSO HEMOPROTEINS, HAPTOGLOBINS
SEE ALSO METALLOPROTEINS, CERULOPUSMIN
SEE ALSO METALLOPROTEINS, FERRITIN
SEE ALSO METALLOPROTEINS, TRANSFERRIN
SEE ALSO PORPHYROPROTEINS, METALLOPORPHYROPROTEINS
SEE ALSO PROTEIN BINDING
SEE ALSO PROTEINS, Z PROTEIN
ROlHL-02835-21 Renal transport carrier for organic
compounds (dogs, rats)
ROlHL-05360-19 Cholesterol biosynthesis and its control
in liver (rats)
** ROlHL-06221-17 Composition and structure of plasma
lipoproteins (human, turkeys, baboons)
ROlHL-08634-15 Enzymic cholesterol synthesis (human.
rats, protozoa, yeast)
** ROlHL-08893-14 Structure and function of membrane
proteins (human)
ROlHL-10933-13 Fat metabolism and atherosclerosis
(rabbits, cattle, human, rats)
ROlHL-10940-13 Lipid transport (rabbits, cattle, chickens)
ROlHL-12085-10 Lipoprotein-carbohydrate metabolism
(human, rats)
ROlHL-14483-08 Energy conservation in heart
mitochondria (cattle, E coli, human)
ROlHL-15263-06 Lecithin-Cholesterol acetyltransferase
(human, rabbits)
ROlHL-15648-06 Lipid metabolism-Transport by lateral
diffusion (human, rabbit, cattle)
ROlHL-16628-05 Regulation of lipid metabolism (rats)
ROlHL-16660-06 Phospholipid-cholesterol and
phospholipid-protein interactions
ROlHL-17371-05 Regualtion of cholesteryl ester levels in
the aorta (swine)
ROlHL-17463-03 Composition and structure of plasma
lipoproteins (human, rabbits)
ROlHL-17879-04 Molecular structure of the ouabain
sensitive ATPase (dogs)
ROlHL-18181-04 Surfactant metabolism -Alveolar cells and
lung disease (mice, rabbits)
** POlHL-18208-04 0007 Center for the study of blood cell
rheology - RBC membrane protein (human)
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
••Onented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
BIO
ROlHL-18255-04 Lipid-protein interactions and calcium
transport (models)
POlHL-18577-03 0005 Lipoproteins -Cell surface
interactions - Chemical synthesis of apolipoproteins and
apoliprotein fragments
ROlHL-18619-03 Transferrin iron binding and transport
properties (chicken, rabbit, human)
ROlHL-18746-02 Chemical studies on proteolipid
apoproteins (cattle)
ROlHL-20365-03 Molecular mechanisms of anion transport
ROlHL-20711-01 Structure-function relationships in red
cell NA-K pumps (goats)
ROlHL-20882-02 Interactions of plasma lipoproteins with
erythrocytes (Rhesus, human)
" P50HL-21006-02 0003 Specialized center of research in
arteriosclerosis - Transport of vitamin A in plasma (human
rat)
ROlHL-21217-01 Ion and 5-hydroxytryptamine transport by
platelets
BIOLOGICAL TRANSPORT, TRANSPORT
PROTEINS, PERMEASES
ROIHL- 17 736-04 Metabolic change during cardiac
ischemia (rats, dogs)
ROlHL-18818-04 Stereochemical mechanism of sickling of
hemoglobin S (human)
BIOLOGICAL TRANSPORT, TRANSPORT
PROTEINS, PERMEASES, GLUCOSE PERMEASES
ROlHL-08893-14 Structure and function of membrane
proteins (human)
R01HL-13237-09 Erythrocytes during early development
(human, animals)
BIOLOGICALS RESOURCES
SEE BIOLOGICAL PREPARATIONS AND STANDARDIZATION
SEE IMMUNOLOGICAL PREPARATIONS (GENERAL)(INCLUDING
CERTIFICATION AND STANDARDIZATION)
BIOLOGY (GENERAL)*
SEE ALSO PHOTOBIOLOGY
SEE ALSO WATER ENVIRONMENT. AQUATIC BIOLOGY
SEE ALSO WATER ENVIRONMENT. MARINE BIOLOGY
** POlHL-20993-02 0009 Population dynamics of arterial
cells in atherogenesis - Mathematical biology-Core
R13HL-22068-01 Conference on The Internal Environment'
(California)
BIOLOGY, LIFE CYCLE
ROlHL-18629-04 Influence of aging and hypertension on
the myocardium (rats)
BIOLOGY, POLYMORPHISM
P01HL-03174-23 0006 Mechanisms of acute vascular
reaction to injury - Atherosclerotic plaque studies using
mosaic analysis (human)
ROlHL-04366-19 Plasminogen-Activation and structure-
function relations (mammals, birds)
P01HL-09011-15 0001 A research and resource program
in blood - Genetic markers of human blood and gene
mapping (human)
POlHL-0901 1-15 0012 A research and resource program
in blood - Theoretical population genetics (human)
ROlHL-15808-06 Role of angiotensinogen in hypertension
and stroke (human, rabbits)
ROlHL-17194-03 Comparison of two inherited forms of
alpha-1-antitrypsin (human)
P60HL-17265-04 0008 Community blood resource center
support - Research-Blood genetic markers as biological
probes (human)
POlHL-17419-04 0001 Studies on mechanisms of
hemostasis - Structure and metabolism of fibrinogen
(human)
R01HL-1788M5 Biosynthesis and degradation of blood
group substances (human, animals)
ROlHL-18612-03 Thin filament control of heart contraction
(cattle)
** POlHL-21016-02 0008 Sickle cell anemia and other
hemoglobinopathies - The clinical variations of sickle cell
anemia
** ROlHL-21665-01 Collagen polymorphism and arterial
structure (monkeys, guinea pigs)
R23HL-22799-01 Interaction of the complement and
coagulation systems (monkeys)
** ROlHL-23194-02 Genetics of hypertension and associated
variables (human)
BIOLOGY, SYSTEAAATIC
SEE ALSO MICROBIAL IDENTIFICATION AND CLASSIFICATION
(TECHNIQUES)
P01HL-08214-15 0048 Chemical and biological properties
of lipids - Lipids in microorganisms and plants
BIOLOGY, SYSTEMATIC, EVOLUTION AND
PHYLOGENY
R01HL-02254-23 Blood coagulation and hemorrhagic
disease (human, animals)
ROlHL-02751-21 Function and metabolism of serum
albumin (mammals, fish, amphibians)
ROlHL-06950-17 Red cell metabolism (human,
vertebrates)
** ROlHL-07047-16 Comparative study of cardiac conduction
system (human, birds, mammals)
(contd)
•lO
ROIHl 08?99 16 Moleculm bioloiy ol htmerylhitn and
htinocyaniii (invtrtabralas)
ROIMI 12486 10 Strucluri lunclion coiiolntion in tho
ttfiuin (tibbits)
ROIHL IMD7 0S P«iiphttil Cdculation and lluid balance
(tish. mammals, human)
ROIHI 18082 03 Irythrocyl* phosphates and vettebiale
(as tianspoit (amphibians, leptiles)
" ROIHI 18868 03 Development ol veitebiale vasculai
contiol systems (irpliles. amphibians)
ROIHL 20800 1/ Neuial basis ol lespiiatory and
vasomotoi activity (cats)
" ROIHL 20961 02 H«mo|lobin Y chain genes Evolution and
inducibility (monkeys, human)
BIOLOGY, SYSTEMATIC, EVOLUTION
BIOCHEMICAL
ROIHL 02212 23 Coagulation ol bluod (human)
ROIHL 04366 19 Plasminogen Activation and structure
lunction relations (mammals, birds)
ROIHL 05556 19 Proteins, lipoproteins Structure and
reactivity (chicken, human, diving mammals)
ROIHL 06221 17 Composition and structure ol plasma
lipoproteins (human, turkeys, baboons)
ROIHL 10642 18 Plasma cholesterol metabolism (human,
macaca)
ROIHL 15026 12 Quantitative genetic control ol protein
synthesis (human, primates, mammals)
ROIHL 1546006 Molecular adaptation Hemoglobin
systems ol lish (marine)
BIOLOGY, SYSTEMATIC, GENETIC STRAINS
POlHL-06835 17 0018 Cardiovascular disease Fatty
acid concentration (rats)
POIHL 06835 17 0019 Cardiovascular disease Fatty
acid distribution (rats)
•* ROIHL 10942 09 Study ol genetic hypertension in rats
P50HL14164 07 0027 A/S SCOR- Comparative and
experimental atherosclerosis Hyper- and
hyporesponsiveness to dietary cholesterol (squirrel monkey)
P50HL-1416407 0028 A7S SCOR -Comparative and
experimental atherosclerosis Hyper- and
hyporesponsiveness to dietary cholesterol (Alrican green
monkey)
*• P50HL-1416407 0029 A/S SCOR -Comparative and
experimental atherosclerosis - Development ol pigeon
substrains
** P50HL-14164-07 0037 A/S SCOR-Comparative and
experimental atherosclerosis - Genetic control ol plasma
cholesterol -Interaction ol dietary tatty acid (monkey)
P50HL-14164 07 0044 A/S SCOR -Comparative and
experimental atherosclerosis - Cell biology-atherosclerosis
project (pigeons)
P50HL-14236-05 0005 Prevention ol premature
arteriosclerosis ■ Genetically hyperlipidemic and
hypolipidemic rats
** ROlHL-1491306 Hypeilension -Genetic inlluence ol kidney
(rats)
POlHL-1683304 0014 Hemoglobin and red cell system in
hemoglobinopathies - Erythrocyte membrane damage in Hb
SS disease (human)
POlHL-17430-05 0001 Control ol coagulation - Porcine
von Willebrand's disease
ROlHL-1 7754-03 Pathogenesis and prevention ol
hypertension sequelae (rats)
ROlHL-18191-04 Models ol hypoxic pulmonary
hypertension (cattle, minipigs)
POlHL-18576-03 0009 Thrombosis research program
project ■ Biology ol factor VII (human, rabbits, cattle)
POlHL-1864603 0003 Studies basic to heart
transplantation - Host responses to xenografts (rodents,
rabbits)
ROlHL-18723-03 Genetic heterogeneity ol acid lipase--
Atherosclerosis (human)
ROlHL-18831-03 Microscopy ol spontaneously hypertensive
arterial lesion (rats)
ROlHL-18848-03 Etiology and development ol congenital
heart disease (dogs, cats)
R01HL-19027-03 Calcium and cyclic AMP in causation ol
hypertension (rats)
** P50HL-19362-02 0004 A/S SCOR-Atherosclerosls in
nonhuman primates - Selective breeding for characters
related to atherosclerosis (baboons)
P50HL-19362-02 0012 A/S SCOR -Atherosclerosis in
nonhuman primates - Induction of chronic hypertension by
salt loading (baboon)
** ROlHL-20176-02 Biochemistry and genetics of salt
hypertension (rats)
ROlHL-20201-01 Hypertension and vascular steroid
receptors (rats)
ROlHL-2044602
(also rats)
M ROlHL-20572-02
hypertension
** ROlHL-20572-02 0001 Hemodynamic relations to
metabolism in hypertension - Hemodynamic and myocardial
functional studies in the SHR (rat)
ROlHL-20861-01 Cardio-respiratory-renal stress reactions
(dogs)
ROlHL-22603-01 Trace metals, vascular activity and
hypertension (rats)
** R23HL-22959-01 Heart development in inherited
cardiomyopathy (hamsters)
NOIHV 62905 02
iiitfiiioM:lero^i\
33
Noil hiiiiijin piimaln models of
Autonomic neuropathy in diabetic mice
Hemodynamic relations to metabolism in
BIOLOGY, SYSTEMATIC, SPECIES
ROim 019/9 22 ArterioscleiOMS in loo «nim«K on
conliolled diets (animiiK)
POIHI 031 /4 23 000/ Mechanisms ol acute vascular
reaction to injuiy Hiviling ol miured myocardium Basal
lamina scallold (hum.in. lats. dogs)
POIHL 031 74 ?3 001 1 Mechanisms ol acute vascular
reaction to injury Mutagen metabolism by artery vnall in
etiology ol atherosclerosis (human, animals)
POIHL 06285 18 0203 Cardiovascular respiratory
physiology and biochemistry Pathways ol lipid transport
in the blood (animals)
P01HL06835 17 0030 Cardiovascular disease Synthesis
and pharmacology ol angiotensin antagonists (rats, cats)
POIHL 07896 15 0033 Environmental biomedical research
program Breathing mechanism in birds
*• POIHL 089 74 14 0024 Natural and experimental
atherosclerosis Atherosclerosis, sterol and lipoprotein
metabolism in nonhuman primates
ROIHL 10612 13 0019 Humoral factors in heart lailure
and hypertension Pathogenesis ol hypertension in the
spontaneous hypertensive rat
POIHL 11351 12 0023 Cellular and molecular
mechanisms of myocardial lunction Energetics ol
mammalian muscle (rats)
** ROIHL 11906 11 Comparative study ol heart lunction
(cats, rats, hedgehogs, squirrels)
POIHL 14580-07 0001 Program project in respiratory
mechanics Micromechanics ol the lung (dogs, rats)
ROIHL 15026-12 Quantitative genetic control of protein
synthesis (human, primates, mammals)
ROIHL 15522-06 Influence ol mannitol on ischemia
cardiac muscle (dogs, cats, rats)
ROIHL 15797-05 Lipid metabolism and atherosclerosis in
primates (monkeys, human, squirrels)
** ROlHL-15888-05 Comparative stereology ol the
myocardium (birds, mammals)
ROIHL 16119-05 Spleen and marrow allografts in
hereditary anemia (mice)
POlHL-16137 05 0001 Alveolar biology - Chemical
characterization of surfactant system -Lipid and lipid
protein fractions
POIHL 16137 05 0008 Alveolar biology - Macromolecular
events in pulmonary cells in toxic environments (animals)
POlHL-16607-05 0003 Calcium ion and control of
cardiovascular function - Calcium transport in
sarcoplasmic membranes (animals)
POlHL-16833-04 0016 Hemoglobin and red cell system in
hemoglobinopathies - Calcium-indiced membrane damage
in Hb SS disease (human, animals)
ROlHL-16860-05 Mossbauer studies of respiratory
hemoproteins
ROlHL-17322-04 Functional characteristics of smooth
muscle isolated from lung (animals)
POlHL-17430-05 0007 Control ol coagulation - Platelet
adhesion, aggregation, ultrasfructure in flowing blood
(human, animals)
ROlHL-1756703 Lipoprotein-cytolytic toxin interaction
(Staphylococcus aureus, mammals, human)
POlHL-17731-04 0003 Physiological basis of pulmonary
disease ■ Comparative physiology (vertebrates)
** ROlHL-17758-04 Development ol collateral ventilation
(dogs, fish, horses)
R01HL-17947-04 Experimental renal and neurogenic
hypertension (human, animals)
ROlHL-17954-03 Narcotics and the circulation (human,
dogs, pigs, monkeys)
ROlHL-18070-04 Regulation of intrapulmonary airways
and vessels (human, animals)
ROlHL-1822604 Mechanism of oxygen supply to tissue
(human, animals)
POlHL-18574-03 0006 Lipoprotein methodology and
biomedical applications - Lipoprotein transformation,
lipolytic enzymes, diet and lipid lowering agents
POlHL-18646-03 0003 Studies basic to heart
transplantation - Host responses to xenografts (rodents,
rabbits)
P50HL-19362-02 0005 A/S SCOR-Atherosclerosis in
nonhuman primates - Hybridization to produce primate
model of atherosclerosis (baboon. Rhesus)
POlHL-19717-02 0001 Response of the lung to injury -
Lung elastic tissue (animals)
ROlHL-20206-02 Carbohydrates-nucleotides and adrenergic
interactions (rabbits, cats, rats)
ROlHL-2035202 Defenses of lung cells against oxygen
toxicity (human, animals)
POlHL-20984-02 0005 Cellular mechanisms in cardiac
hypertrophy - Neurohumoral receptors in cardiac growth
and compensatory hypertrophy (animals)
ROlHL-21032-02 Injury, wall thickness, and arterial wall
oxygenation (dogs, rabbits)
ROlHL-21308-01 Prostaglandins and local control of the
circulation (rats, dogs)
ROlHL-21850-01 Calcium transport in the hypertrophied
myocardium (rats, animals)
R01HL-22079-0I Heart receptor sites for digitalis and
steroid hormones (animals)
ROlHL-22500-01 Conversion of choline to
phosphatidylcholine in lung (rabbits, pigs)
POIHI 72619 01 0001 Cellular mwhanismt ol h»il
lllluct C«ll membrani itolilion and ixon-.lilution IHnf.
Iimbi)
BIOMATERIALS
Ml Al'.O HKJMI DICAl [NClNEfRINC, BIOtOCICAl P(JW(H
SrSMMS
Sff AlSOttlOOn COAtiUIAIION ANIIIHROMBOCf NIC
StlRIAtl
SEE Also PROSIHfSI',
SEE ALSO SUHGICAl ADHESIVE ">
SEE ALSO TISSUE COMPATIBILIIY IRANSPUNl. IMI'IANI
POIHL 0631? 1/ 0030 Surgical cardiology Total
artificial heart (calves)
•• POIHI 0631? 1/ 0043 Surgical cardiology The
cylindrical ventricular assist device (dogi)
*• POIHL 06370 1/ 0013 Cardiopulmonary and renal
pathology research center Morphologic analysis ol
vascular prosthesis (human, dogs)
POIHL 11414 11 0027 Thrombosis and atherosclerosil
program Thermal memory wire lilter to prevent pulmonary
embolism (human, dogs)
ROIHL 11418 09 Poly diaminophosphazenes
ROIHL 11945 10 Synthesis ol artilicial lung and kidney
systems (sheep, mice, swine)
POIHL 12373 10 0003 Cardiopulmonary physiology and
pathophysiology Myocardial function in man
ROIHL 12839 09 Flow, transport and membrane
phenomena in blood (human)
M POIHL 13330 08 Mechanical circulatory support
POIHL 1333008 0031 Mechanical circulatory support -
Hemodynamics ol cardiac prosthesis
POIHL 13330 08 0034 Mechanical circulatory support In
VIVO test and evaluation ol left ventricular bypass pumps
(human, cattle)
** POIHL 1333008 0056 Mechanical circulatory support
Blood compatibility linings (calves)
POlHL-13330-08 0059 Mechanical circulatory support
Physiologic evaluation of circulatory assistance (cattle)
** POIHL 13330-08 0062 Mechanical circulatory support -
CORE facilities
ROlHL-13426 09 Left ventricular bypass for myocardial
infarction (cattle, human)
** POlHL-13737-07 0002 Assisted circulation - U-shaped
mechanical auxiliary ventricle (dogs)
POlHL-13737-07 0005 Assisted circulation - Piezoelectric
assist device (animals)
POIHL 13737 07 0026 Assisted circulation - Hemostatic
mechanism (human, dogs)
POlHL-13737-07 0032 Assisted circulation ■ The dynamic
aortic patch (human, dogs)
POlHL-13737-07 0033 Assisted circulation - Autologous
bioprosthetic grafts for coronary artery bypass surgery
(human, dogs)
M POlHL-13738-08 Cardiac assist devices and artificial
hearts
POlHL-13738-08 0002 Cardiac assist devices and
artificial hearts - Total replacement with artificial heart
(calves, sheep, ponies)
** POlHL-13738-08 0003 Cardiac assist devices and
artificial hearts - Pathophysiological effects of the artificial
heart (calves)
** POlHL-13738-08 0004 Cardiac assist devices and
artificial hearts - Hematological evaluation of prosthetic
materials (calves)
** POlHL-13738-08 0005 Cardiac assist devices and
artilicial hearts ■ Development of new materials for
artificial heart and assist devices (sheep, dog)
** ROlHL-13803-07 Advanced cardiac valvular and vascular
prosthesis (dogs, baboons)
ROlHL-13988-07 Elimination of reoperative cardiac
pacemaker surgery (dogs)
R01HL14126-17 Effect of function on grafts and implants
of collagen (dogs, monkeys)
M POlHL-15195-04 Program project in biological materials
** POlHL-15195-04 0001 Program project in biological
materials - Design and synthesis
** POlHL-15195-04 0002 Program project in biological
materials - Structural and surface characterization
** P01HL15195-04 0003 Program project in biological
materials ■ Mechanical evaluation and fabrication
** POlHL-15195-04 0004 Program project in biological
materials - Biological evaluation and surface interaction
studies (dogs)
** POlHL-1548606 0004 Studies on thrombosis ■
Thrombosis, intravascuair coagulation, platelet aggregation
(dogs)
ROlHL-15668-06 Extracorporeal respiratory gas exchange-
A new approach (dogs)
R01HL16154-05 Membrane lung perfusion for acute
respiratory failure (sheep, baboons)
POlHL-16387-04 0006 The blood vessel and
thrombogenesis - Mechanism of delayed vessel graft lailure
(dogs, rabbits)
ROlHL-16582-05
" ROlHL-16921-05
materials
ROlHL-17369-04
metabolism (monkeys)
POIHLI 7430-05 0007 Control ol coagulation - Platelet
adhesion, aggregation, ultrastructure in flowing blood
(human, animals)
(contd)
Artificial lungs (dogs)
Synthetic hydrogels as blood tolerable
Arterial bypass surgery-Structure and
•Excludes routine meltiodology OR covers only general projects wtiich preclude indexing at the specific level.
••Oriented significantly to above subject.
M Grant has subprojects descnbing specillc research aspects.
See Appendix lor investigator's name and grant number.
BIO
Artificial heart and related problems
R01HL-17623-0S Initial events in thrombus formation on
surfaces (humana rats)
R01HL17969-04 Function and structure of semilunar
valves (dogs)
R01HL18084-03
(calves)
ROlHL-18321-03 Fluid shear or magnetic alignment of
blood components (human)
ROlHL-18441-03 Guidelines for polymers acting as elastin
substitutes
POlHL-18576-03 0003 Thrombosis research program
project - Biocompatible materials
P01HL18576-03 0010 Thrombosis research program
project - Evaluation of non-thrombogenic materials (cattle)
ROIHL 1864403 Prosthesis for aortocoronary bypass
(dogs, baboons)
ROlHL-18764-03 Biosorbable thromboresistant surfaces
(dogs, rats, swine, human)
R01HL'190S5-03 Platelet function during extracorporeal
perfusion (human, mammals)
ROlHL-19173-03 Analysis of blood trauma from
microporous oxygenators (human, dogs, rabbits)
ROlHL-19350-02 Prevention of thrombosis by applied
electric fields (sheep)
ROIHL- 194 19-03 Cellular interactions with foreign
materials (mammals)
R01HL-2O037-O2 Left ventricular-aortic bypass and
composite prosthesis (sheep, swine, cattle)
R01HL-20073-02 Blood compatible materials by fluid
perfusion (human, dogs)
ROlHL-20079-02 Thromboresistant material
ROlHL-20079-02 0002 Thromboresistant material -
Thromboresistant materials (sheep)
ROlHL-20079-02 0003 Thromboresistant material - Blood
surface interactions (human, cattle)
ROlHL-20163-02 Competitive coronary flow in native and
graft vessels (dog)
ROlHL-20251-02 A novel approach to nonthrombogenic
polymer surfaces (sheep, cattle)
ROlHL-20313-02 Surface-induced thrombosis-Modification
of albumin variants (human, goat)
ROlflL-203 56-02 Development and evaluation of an
artificial heart (calves)
ROlHL-20554-02 Memory-alloy-filters for venous emboli
(dogs)
ROlHL-21001-01
vascular grafts
ROlHL-2 1194-02
biomaterials
R23HL-21271-02 Extracorporeal circulation and protein
denaturatlon (human)
R01HL-21632-02 Development of a transcutaneous power
transfer system (cattle)
R23f4L-21805-Cl Tissue cell Interactions with vascular
prostheses (human, rats, mice)
R01HL-22I 10-02 Healing complications in vascular
grafting (dogs)
POlHL-22163 01 Surface thrombogenesis -Mechanisms and
prevention
POlHL-22163-01 0001 Surface thrombogenesis-
Mechanisms and prevention - Initial blood protein and
platelet interactions with biomaterials (baboons)
POlHL-22163-01 0002 Surface thrombogenesis -
Mechanisms and prevention - Laser-scattering detection of
microemboli in blood flow (baboons)
POlHL-22163-01 0003 Surface thrombogenesis -
Mechanisms and prevention ■ In vivo mechanisms of
biomaterial thrombogenesis and its prevention (baboons)
POlHL-22163-01 9001 Surface thrombogenesis -
Mechanisms and prevention - Polymers for studing blood-
material interactions core
ROlHL-22338-01 Platelet adhesion and aggregation in a
flow chamber (human)
ROIHL-22455-01 Platelet concentration in the marginal
layer (dogs, human)
R01HL-22585-01 Plasma proteins adsorbed to artificial
organs (human, rabbits)
ROlHL-23899-01 Flow and flexing at blood/biomaterial
interfaces
N01HV-12017-15 Fabrication of grafted hydrogel coatings
for plastic heart assist devices
NOlHV-12054-14 Development of intimal linings (human,
cattle)
NOlHV-12065-16 Fabrication of implantable artificial heart
devices (animals)
NOlHV-32913-11 Study electrodeless glow discharge for
modifying polymer surface
N01HV-32917-08 Materials development and testing
NOlHV-32919-12 Material development and testing
heparinization processes
Protein and thrombus deposition on
Development of antithrombogenic plastic
NOlHV-32949-11
medical devices
NOlHV-3295008
NOlHV-32953-10
NOlHV-32959-10
devices
NOlHV-4291413
(cattle)
NOlHV-42928-07 Continued development of carbon film
deposits for prosthetics
N01HV42960-07 Development and evaluation of cardiac
prostheses (calves)
Modification of silicon elastomers for
Blood compatible poly-electrolytes
Materials compatible with blood (dogs)
Development of materials for heart assist
Solenoid left ventricular assist system
34
NOlHV-42961-Oe Evaluation of biomaterials in contact
with blood (dogs)
NOlHV-42969 06 Interactions of natural and chemically
modified biopolymers with blood (dogs)
NOlHV-629 11-04 Vena cava ring tests of biomaterials In
dogs
Test polymers for circulatory assist
NOlHV-729 18-01
devices
NOlHV-72919-01
divices
NOlHV-72933-01
Test polymers for circulatoiy assist
Electrical energy transmission technique
development (dogs)
NOlHV-72934-01 Development of a left heart assist blood
pumps (human, cattle)
NOIHV 72937-00 Left heart assist blood pumps (calves)
NOlHV-72938-01 Development of a left heart assist blood
pump
NOlHV-72939-01 Develop and evaluate left heart assist
blood pumps (human, calves, pigs)
BIOMATERIALS, TISSUE SUPPORTING FRAMES
** POlHL-13330-08 0056 Mechanical circulatory support -
Blood compatibility linings (calves)
POlHL-13737 07 0032 Assisted circulation The dynamic
aortic patch (human, dogs)
POIHL 13738-08 0001 Cardiac assist devices and
artificial hearts - Cardiac assist devices (human, sheep)
*• POlHL-13738-08 0005 Cardiac assist devices and
artificial hearts - Development of new materials for
artificial heart and assist devices (sheep, dog)
R01HL16582-05 Artificial lungs (dogs)
ROlHL-18644-03 Prosthesis for aortocoronaiv bypass
(dogs, baboons)
ROlHL-18764-03 Biosorbable thromboresistant surfaces
(dogs, rats, swine, human)
ROlHL-221 10-02 Healing complications in vascular
grafting (dogs)
POlHL-22163-01 0003 Surface thrombogenesis -
Mechanisms and prevention - In vivo mechanisms of
biomaterial thrombogenesis and its prevention (baboons)
ROlHL'23542-01 Pulmonary vascular smooth muscle cell
dynamics (rat, rabbit)
** NOlHV'12054-14 Development of intimal linings (human,
cattle)
** NOlHV-12060-18 Tissue cultured endothelium for vascular
prosthetic devices (human, animals)
NOlHV-72934-01 Development of a left heart assist blood
pumps (human, cattle)
NOlHV-72939-01 Develop and evaluate left heart assist
blood pumps (human, calves, pigs)
** NOlHV-81388-20 Microfiber substrate for growth of intimal
linings in circulatory assist devices
BIOMATHEMATICAL AND COMPUTER SCIENCES
STUDY SECTION
SEE COMPUTER AND BIOMATHEMATICAL SCIENCES STUDY
SECTION
BIOMATHEMATICS
SEE MATHEMATICS, BIOMATHEMATICS (GENERAL)
BIOMECHANICS
SEE BIOPHYSICS. BIOMECHANICS
BIOMEDICAL DATA COMPUTER PROCESSING
SEE BIOMEDICAL SYSTEMS AUTOMATED. COMPUTER
PROCESSING OF LABORATORY DATA (GENERAL)
BIOMEDICAL ECONOMICS
SEE HEALTH ECONOMICS
BIOMEDICAL EDUCATION
SEE EDUCATION. HEALTH OCCUPATIONS
BIOMEDICAL ENGINEERING
SEE ALSO BIOPHYSICS (GENERAL)*
M POlHL-1 1307-12 Biophysical studies in pediatric
cardiology
** POIHLI 1307-12 9002 Biophysical studies in pediatric
cardiology - Biomedical engineering
** ROlHL-12493-10 Bioengineering analysis of microvascular
function (cats, rabbits)
POlHL-13737-07 0025 Assisted circulation - Driving
system based on quantitative criteria (human, dogs)
** POlHL-14985-07 0018 Adaptation to hypoxia ■
Bioengineering core
ROIHL-17821-03 Cavitation phenomena near prosthetic
devices
** ROlHL-19350-02 Prevention of thrombosis by applied
electric fields (sheep)
M
ROlHL-20079-02
R01HL-20219C2
(rats)
ROIHL 21188-02
desquamation
NOlHV-72933-01
Thromboresistant material
Cryopreservation of the isolated heart
Pulsatory water flux and endothelial cell
Electrical energy transmission technique
development (dogs)
BIOMEDICAL ENGINEERING, BIOLOGICAL
POWER SYSTEMS
POlHL-10436-13 0006 A multidisclplinary study of
congenital heart disease - Ventricular blood pumps and
valves (human, cattle)
** ROlHL-13988 07 Elimination of reoperative cardiac
pacemaker surgery (dogs)
BIO
ROlHL-18084-03 Artificial heart and related problems
(calves)
R01HL-2035e-02 Development and evaluation of an
artificial heart (calves)
Catheter ventricular defibrillation studies
Signal analysis of turbulence study In
** ROlHL-20629-02
(dogs)
ROlHL-2083502
blood
** ROlHL-21632-02 Development of a transcutaneous power
transfer system (cattle)
ROlHL-2167401 Development of automatic implanted
defibrillator (dogs, cattle)
** NOlHV-72971-01 Energy converters to control heart assist
devices (human, cattle)
** NOlHV-72976-02 Energy converters to control heart assist
devices (human, cattle)
** NOlHV-82919-00 Development of percutaneous energy
transmission systems
BIOMEDICAL ENGINEERING, INSTRUMENTATION
CENTERS
** ROlHL'11119-17 Amino acid analyzer for biochemical
research
** P01HL11414-11 0036 Thrombosis and atherosclerosis
program - Electron microscopy core facility
POlHL-12373-10 0018 Cardiopulmonary physiology and
pathophysiology - Biochemistry laboratory
** POlHL-12373-10 0019 Cardiopulmonary physiology and
pathophysiology - Free ranging animal facility
ROlHL-20356-02 Development and evaluation of an
artificial heart (calves)
BIOMEDICAL ENGINEERING, INSTRUMENTATION
CLINICAUY ORIENTED
NOlHB-22922-08 Develop effective therapy for sickle cell
disease (human, dogs)
** N01HB-e2962-02 Red cell distributions in cyanate-treated
blood (human, sheep)
ROlHL-03181-21 0020 Hemodynamics as applied to
surgical problems - Blood flow measurement -Cardiac
output and regional flows (dogs)
** ROlHL-04651-19 Remote stimulation by radio-frequency
transmission (dogs, human)
M POlHL-04664-18 Cardiovascular and lung dynamics
** POlHL-04664-18 0001 Cardiovascular and lung dynamics
- X-ray projection image videodensitometry (dogs)
" P01HL-04e64-18 0002 Cardiovascular and lung dynamics
- X-ray cross section imaging of organs (dogs)
** POlHL-04664-18 0003 Cardiovascular and lung dynamics
- X-ray projection image videometry (human, dogs)
** POlHL-04664-18 0004 Cardiovascular and lung dynamics
- X-ray cross section imaging of the circulation (dogs)
** POlHL-04664-18 0005 Cardiovascular and lung dynamics
- Applications of current research, equipment and
techniques
** POIHL-04664-18 0006 Cardiovascular and lung dynamics
- Cross section imaging of organ functions using emitted
radiation (dogs)
" POlHL-04664-18 0007 Cardiovascular and lung dynamics
- Development and application of ultrasound imaging
techniques
** P01HL04664-18 0008 Cardiovascular and lung dynamics
- Micrographic video imaging technique
** P01HL04664-18 0009 Cardiovascular and lung dynamics
- Biological signal and image processing techniques (dogs)
** POlHL-0466418 0010 Cardiovascular and lung dynamics
- Left ventricular dynamics (human)
POlHL-04664-18 0015 Cardiovascular and lung dynamics
- Computer system for the cardiovascular laboratory
** ROlHL-04666-19 Artificially paced hearts-Technology,
physiology (human, dogs)
P01HL-06285-18 0146 Cardiovascular-respiratory
physiology and biochemistry - Pathogenesis and detection
of hypoxic pulmonary edema (human, animals)
** POlHL-06308-18 0012 Mechanisms and therapy of
circulatory disease - Echocardiographic evaluation of
hemodynamics of arrhythmia (human)
** POlHL-06308-18 0042 Mechanisms and therapy of
circulatory disease - Echocardiographic assessment of
arrhythmias-Myocardial tissue type (human, dogs)
** POlHL-06308-18 0043 Mechanisms and therapy of
circulatory disease - Exercise and echocardiographic
examining techniques (human)
** POlHL-06308-18 0044 Mechanisms and therapy of
circulatory disease - Echocardiography to determine site of
ectopic impulse formation (human, dogs)
" POlHL-06312-17 0030 Surgical cardiology - Total
artificial heart (calves)
** POlHL-06312-17 0041 Surgical cardiology - A
servomechanism for left ventricular assist (human, dogs,
sheep)
P01HL06314-17 0065 Immunologic mechanisms in
cardiovascular disease - Transplantation biology and
clinical transplantation
M POlHL-07293-17 Non-invasive cardiovascular
measurements
** POlHL-07293-17 0041 Non-invasive cardiovascular
measurements - Ventricular volumes and dimensions
(human)
" POlHL-07293-17 0042 Non-invasive cardiovascular
measurements - Ventricular imaging software (human)
(contd)
*E>cludes routine methodok)gy OR cavers only general projects which preclude indexing at the specific level.
"Oiioited significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
BIO
* POIHLO??93 W 0043 Non Invislv* cardlovajcultr
metsuranitnis (CHO Oopplir instruniinlalion loi caidiac
maasuftmanti (human)
* POIHI 07293 U 0044 Non mvasiwa caidiovasculai
maasuramenti Cardiac dupla> scannai
* PO1H107293 W 004S Non invasiva caid(ovasculai
maasuicmanls Cardiac scannar transducai position
locatini systams (human)
* POIHI 07293 17 0046 Non invasive cardiovascular
measuramenis Cardiac scanner signal processors
* POIHI 07293 17 0047 Non invasive cardiovascular
measurements Cardiac scanner system software
* P01H107293 17 0048 Noninvasive cardiovascular
measurements Cardiac scanner recording and display
systems component
* POIHL 07293 17 0049 Non invasive cardiovascular
maasuiements Cardiac scanner engineering evaluation
and error analysis
'* POIHL 07293 17 0050 Noninvasive cardiovascular
measurements Cardiac dimensions measurements
engineering evaluation and error analysis
" P01H107293 17 0051 Noninvasive cardiovascular
measurements Physiologic evaluation of duplex scanner
(dogs)
"* P01HL0729J 17 0052 Noninvasive cardiovascular
measurements Clinical evaluation of the duplex scanner
(human)
•* PO1H107293 17 0053 Non invasive cardiovascular
measurements Clinical evaluation of cardiac dimensions
using the duplex scanner (human)
*• POlHL-07293-17 0054 Non-invasive cardiovascular
measurements Detection of arterial occlusive disease
(human)
** PO1HL07293 17 0055 Noninvasive cardiovascular
measurements Peripheral vascular transducer position
locating system
** P01HL0729317 0056 Non invasive cardiovascular
measurements Peripheral vascular system software
** POlHL-0729317 0057 Noninvasive cardiovascular
measurements Peripheral vascular scanner engineering
evaluation and error analysis (human)
** POIHL 07293-17 0058 Non-invasive cardiovascular
measurements ■ Peripheral duplex scanner physiologic
evaluation
** POlHL-07293-17 0059 Noninvasive cardiovascular
measurements - Intracardiac blood flow measurement
(human)
ROlHL-07605-16 Congenital heart disease research
program (human, dogs)
POlHL-07896-15 0036 Environmental biomedical research
program - Respiratory heat loss in deep diving (infants,
dogs)
P01HL0868215 0006 Regulation of the cardiovascular
system ■ Cardiovascular studies of mammalian hibernators
(sciuromorpha)
POlHL-08805-15 0045 Regulation of ventilation and
pulmonary circulation - Integrated description of
neurochemical respiratory control system
ROlHL-09609-11 Lung volume and breathing mechanics
during anesthesia (human)
ROlHL-09711-13 Instantaneous blood (low in ascending
aorta (human, dogs)
** R01HL0983112 Effect of resistivity variations on
electrocardiogram (human)
R01HL1041712 Multiple systems in electrocardiography
(human)
** P01HL10436-13 0006 A multidisciplinary study of
congenital heart disease - Ventricular blood pumps and
valves (human, cattle)
** P01HL1131012 0093 l^echanisms of cardiovascular
disease ■ Multiple dipolc electrocardiogram project (human,
dogs)
** POlHL-11310-12 9002 Mechanisms of cardiovascular
disease ■ Core support-centralized electronic laboratory
** POlHL-11414-11 0024 Thrombosis and atherosclerosis
program ■ Radiographic demonstration of small coronary
arteries (human, dogs)
** P01HL114I411 0027 Thrombosis and atherosclerosis
program ■ Thermal memory wire filter to prevent pulmonary
embolism (human, dogs)
ROlHL-11717-09 Effect of stenotic obstructions on flow in
arteries (dogs)
** ROlHL-1 194510 Synthesis of artificial lung and kidney
systems (sheep, mice, swine)
** ROlHL-1230708 Non-surgical treatment of congenital
heart disease (human, dogs)
** POlHL-1237310 0003 Cardiopulmonary physiology and
pathophysiology - Myocardial function in man
R01HL-1261110 Basic and clinical studies of the ST-T
deflection (human, dogs)
R01HL-1271510 Dynamic cardiovascular measurement
using ultrasound
** POlHL-12738-10 0123 Physiologic pharmacology and its
clinical applications - Ventricular assistance and
preservation (human, dogs)
POlHL-12738-10 0128 Physiologic pharmacology and Its
clinical applications ■ Recording electrograms from
specialized cardiac tissues (human, dogs)
POlHL-12738-10 0131 Physiologic pharmacology and its
clinical applications - Evaluation of intracardiac shunts by
contrast echocardiography (dogs)
3S
ROIHI 12839 09 Mow. transport and membrane
phenumgna in blood (human)
ROIHI 13036 08 Coronary Ihrombojiiftttcli on
myociiidium anil in vivo dftnrlion (dogs, monkeys)
POIHI 13330 08 Mechanical circulatory support
POIHI 13330 08 00.11 Mechanical circulatory support
Hemodynamics of cardiac prosthesis
POIHL 1333008 0034 Mechanical circulatory support In
VIVO test and evaluation ol lelt ventricular bypass pumps
(human, cattle)
POIHL 13330 08 0056 Mechanical circulatory support
Blood compatibility linings (calves)
POIHL 13330 08 0059 Mechanical ciiculatory support
Physiologic evaluation ol circulatory assistance (cattle)
POIHL 1333008 0062 Mechanical circulatory support
CORE facilities
ROIHL 1342609 Left ventricular bypass for myocardial
infarction (cattle, human)
POIHL 13737 07 Assisted circulation
' POIHL 13737 07 0005 Assisted circulation Piezoelectric
assist device (animals)
' POIHL 13737 07 0006 Assisted circulation Portable
driving unit for permanent assist devices (dogs)
' POIHL 13737 07 0008 Assisted circulation Phase shift
balloon pumping alternate designs
• POIHL 1373707 0013 Assisted circulation ■ Incorporation
of sensors (human, dogs)
• POIHL 13737 07 0025 Assisted circulation Driving
system based on quantitative criteria (human, dogs)
P01HL13737 07 0028 Assisted circulation Clinical
studies of intraaortic balloon pumping
POIHL 1373707 0032 Assisted circulation The dynamic
aortic patch (human, dogs)
POlHL-1373707 0039 Assisted circulation ■ Computer
controlled Intraortic balloon pumping
I P01HL1373808 Cardiac assist devices and artificial
hearts
* POIHL 13738-08 0001 Cardiac assist devices and
artificial hearts Cardiac assist devices (human, sheep)
* P01HLI373808 0002 Cardiac assist devices and
artificial hearts Total replacement with artificial heart
(calves, sheep, ponies)
ROlHL-1380307 Advanced cardiac valvular and vascular
prosthesis (dogs, baboons)
♦ POlHL-13851-16 Cyclotron produced isotopes In biology
and medicine (human, animals)
* ROIHL 13988-07 Elimination of reoperative cardiac
pacemaker surgery (dogs)
P50HL-1413607 0005 Pulmonary SCOR-Aitways
obstructive diseases - Radiographic studies of airways
obstructive disease (human)
P50HL-14136-07 0017 Pulmonary SCOR-Airways
obstructive diseases ■ Pediatric airways obstructive disease
(human)
P50HL-141 36-07 9002
obstructive diseases
P50HL-14136-07 9007
obstructive diseases
P50HL-14187-07 0008
Pulmonary SCOR-Airways
Physiology core (human, animal)
Pulmonary SCOR-Airways
Special facilities core
Pulmonary SCOR-Chemical
Pulmonary
mediators in pulmonary vascular responses
thromboembolism (dogs, human)
P50HL14187-07 0016 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses - Core
pathology service (dogs, rabbits, human)
P50HL142 14-07 0036 Newborn lung center for hyaline
membrane disease - Core-Blomedlcal engineering
P50HL1421807 0013 Pulmonary SCOR -Newborn lung
center ■ Longitudinal study of ROS-Monitoring fetal P02
and PC02 during labor (human)
P50HL-142 18-07 0014 Pulmonary SCOR -Newborn lung
center • Longitudinal study of RDS-Monitoring fetal
breathing movements (human)
POlHL-144 14-07 0014 Environmental influences on
cardiorespiratory and cellular functions - Temperature and
acid-base status in tissues, cells, and subcellular system
POlHL-144 14-07 9003 Environmental influences on
cardiorespiratory and cellular functions - Machine and
electronics shop -Core facility
POlHL-14580-07 0005 Program project in respiratory
mechanics - Development and evaluation of tests of
pulmonary function (human)
R01HL14644-05 Optimization diastolic augmentation and
systolic sink (dogs)
R01HL14645-07 Blood flow measurement by ultrasonic
catheter tip methods (human, dogs)
ROlHL-14688-05 Myocardial assessment by inverse
electrocardiography (monkey)
' ROlHL-14785-07 Ultrasonic scattering for tissue
characterization (dogs, cattle, human)
' ROlHL-150 15-07 New concepts In cardiac ultrasound
technology (human)
' ROlHL-15247-05 Extending the life of Implanted
pacemakers (dogs, human)
ROlHL-15270-06 Local mechanical properties of the aortic
tissue (dogs, pigs)
ROlHL-1559305 Prolonged extracorporeal cardiopulmonary
support (rats, sheep, rabbits)
POlHL-15596-05 0001 Coagulation, fibrinolysis,
hemostasis and hepatitis ■ Defibrination (human)
* ROIHL 15668-06 Extracorporeal respiratory gas exchange-
A new approach (dogs)
• ROIHI 15/81 06 (iuided v«4(ul»i ublittiition ol (.N",
vatcuUr lesions (human)
ROIHI 160/6 06 I krtiophy vokjiiy o( librillalioo and
dafibrillation (human)
ROIHI 16154 O'j Membrane lung peflusion lor atutr
respiratory (allure (sheep, baboons)
• ROIHL 16260 04 Development of clini(;al cine ullnsound
cardiography
'• POIHL 1638/04 0005 The blood vessel and
Ihrombogenesis Fluid enginaerin| coniidtrations in
Ihrombogenesis
'* ROIHI 16484 04 Radiographic ventriculomelry for coronsry
heart disease (human)
'• ROIHL 1648/05 Computer controlled two dimensional
echocardiography
>* ROIHL 16582 05 Artificilllungi (dogs)
** ROIHL 16759 05 Ultrasonic measurement of cardiac
geometry and flow
ROIHL 16791 03 Computer linkage lor a dual camera
system
•* ROIHL 16830 05 Non invasive determination of aortic
blood velocities (human)
POIHL 16851 04 0009 Human red cell membrane in
health and disease Blood cell properties in circulatory
regulation (dogs, rabbits)
** ROIHL 16901 05 Multipolar linkage between heart
geometry and surface (human, dogs)
ROIHL 1690804 Myocardial function, risk factors and
future CHO (men)
ROIHL 1690904 Myocardial (unction, risk (actors and
(uture CHD (men)
POIHL 16910 05 0002 Regulation o( the peripheral
circulation Coronary circulation (dogs)
P01HL1691005 0005 Regulation of the peripheral
circulation Control of circulation by baroreceptor and
chemoreceptor reflexes (dog. monkey)
P60HL- 17269-04 0026 National heart and blood vessel
research and demonstration center Dynamics of ischemic
heart disease (human, dog)
P60HL- 17269-04 0029 National heart and blood vessel
research and demonstration center Clinical application of
circulatory assistance (human)
** P60HL1726904 0030 National heart and blood vessel
research and demonstration center Cardiovascular
engineering laboratories (human)
" P60HL- 1726904 0032 National heart and blood vessel
research and demonstration center ■ Clinical circulatory
assist device fabrication
M P01HL17421-05 Regulation and exchange In the
microcirculation
" P01H11742105 0006 Regulation and exchange in the
microcirculation - Core facilities -Optical instrumentation
facility
** P01HL17421-05 0007 Regulation and exchange in the
microcirculation - Core facllities-fluorometric measurement
methods for microcirculation
M ROlHL-17543-03 Magnetic tracers for diagnosis of lung
disease
** ROlHL-17543-03 0001 Magnetic tracers for diagnosis of
lung disease • Chronic, interstitial lung disease (human,
rabbits)
** ROlHL-17591-03 Development of electromagnetic
rheoanglography (human, dogs)
** ROIHL- 17604-03 Wearable blood pressure and ECG
recording system
P50HL-17648-04 0004 Study of ischemic heart disease -
Radionuclide imaging studies (human, pig)
P50HL-1764804 0021 Study of ischemic heart disease ■
Biventricular contractile responses to acute myocardial
infarction (mammals)
** P50HL-17651-04 0016 Ischemic heart disease specialized
center of research - Retroperfusion of coronary venus
circulation with therapeutic agents (dogs)
** P50HL-17651-04 0023 Ischemic heart disease specialized
center of research - Development of multipurpose catheter
for monitoring and electronic pacing
** P50HL17651-04 0035 Ischemic heart disease specialized
center of research - Core facillties-Biomedical engineering,
biophysics
P50HL-17651-04 0037 Ischemic heart disease specialized
center of research • Measurement of coronary venous
outflow by thermodllution (human)
" P50HL-17651-04 0047 Ischemic heart disease specialized
center of research ■ Clinical core-Automated arrhythmia
monitoring system
P50HL-1765504 0012 Study of ischemic heart disease -
DATA management
** P50HL-17665-04 0027 Study of Ischemic heart disease ■
Positron Imaging of regional myocardial perfusion (human,
dog)
** P50HL17667-04 0030 Study of ischemic heart disease -
Computerized clinical data acquisition and processing
" P50HL-17667-04 0042 Study of Ischemic heart disease -
Core-Central instrumentation and software
P50HL-1767004 0008 Study of Ischemic heart disease -
Surgical treatment of cardiac rhythm disorders (human,
dogs)
** P50HL-17670-04 0014 Study of Ischemic heart disease -
Real time ultrasound Imaging In ischemic heart disease
(human, dog)
(contd)
•Excludes routine methodokigy OR covers only general projects which preclude indexing at the specific level.
••Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
BIO
Artificial heart and related problems
Preprocessor system for cardiograms
P50HL-17682-04 0014 Study of ischemic heart disease -
Myocardial ischemia-Instrumentation and technique (dogs.
baboons)
ROlHL-17769-03 New methods of studying blood
coagulation kinetics
ROlHL-17826-04 Oxygen delivery to tissue (rat, dog)
ROlHL-1793104 Normalized body surface potential maps
(children)
ROlHL-17974-03 External pneumatic compression in deep
venous thrombosis (human)
R01HL18040-04 Waveform dependency in defibrillation
(calves)
R01HL18084-03
(calves)
ROlHL-18144-03
(human)
ROlHL-1819003 Myocardial blood flov» in acute
myocardial infarction (human, dogs)
ROlHL-18256-01 Optical properties of platelets and
erythrocytes (rabbits, dogs, human)
R01HL18398-04 Mechanisms of delayed and asymetric
ventricular conduction (human, dogs)
ROlHL-18492-03 Measurement of regional coronary flow
reserve (human, dogs)
POlHL-1857403 Lipoprotein methodology and biomedical
applications
POlHL-18574-03 0001 Lipoprotein methodology and
biomedical applications - Ultracentrifugal and
eleclrophoretic lipoprotein methodology -Applications
POlHL-18576-03 0001 Thrombosis research program
project - Platelet damage from physical forces and
artificial surfaces (human)
ROlHL-18644-03 Prosthesis for aortocoronary bypass
(dogs, baboons)
POlHL-18646-03 0010 Studies basic to heart
transplantation - Development and study of a heart
preservation chamber (dogs, sheep)
P01HL18708-03 0010 Oxygen, energy and contractility in
cardiac tissue • Tissue oxygen utilization (rats, dogs)
ROlHL-187 10-02 Non-invasive reflection oximetry in
peripheral tissue (dogs)
ROIHL-1872503 Light-scattering studies of the sickling
process (human)
ROlHL-18808-04 0003 Prediction and prevention of
sudden cardiac death - Technical support (computer)
ROlHL-18947-02 Indirect mean arterial pressure
(mammals)
ROlHL-18968-03
tomography
ROlHL-18977-03 Non-invasive diagnosis of peripheral
arterial disease (human, dogs)
ROlHL-19003-03 High precision densitometry of coronary
angiograms
ROlHL-19019-03
flow monitoring
ROlHL-19038-02 Plethysmographic evaluation of carotid
blood flow (human, rabbits, dogs)
ROlHL-19065-02 Molecular oxygen in biological fluids
Rapid specific micro measurement of
Computer technology for transaxial
Accurate transcutaneous Doppler blood
Laser spectroscopy of lipoproteins
Measurement of airways mechanics
Heterogeneity of regional myocardial
ROlHL-1908302
blood cholesterol
ROlHL-19095-03
(human)
" ROIHL-19118-03
(human, dog)
ROlHL-19135-04
blood flow (dogs)
** P50HL-19153-02 0008 SCOR-Pulmonary edemas-Eitology.
pathogenesis ■ Core-Biomedical engineering
P50HL-19170-02 0008 Harvard pulmonary SCOR -Chronic
diseases of the airways - Multiple-transient artificial
coughing (dogs, human)
P50HL-19170-02 0010 Harvard pulmonary SCOR -Chronic
diseases of the airways - Computer Core
** P50HL-I9I87-02 0009 Pediatric pulmonary SCOR-Hyaline
membrane disease - Non-invasive measurement and
monitoring of arterial oxygen tension (dogs, sheep)
** P50HL-19190-02 0009 Pulmonary SCOR-Pathophysiology,
management of IRDS - Developing non-invasive neonatal
pulmonary monitoring systems (rabbit, human)
ROlHL-19275-03 Characterization of collateral blood
vessels (dogs)
** R01HL-I9352-03 Respiratory heat and water loss in
neonates
•* P50HL-19362-02 0011 A/S SCOR -Atherosclerosis in
nonhuman primates - Chronic hypertension induced by
operant conditioning techniques (baboon)
" ROlHL-19414-03 Protection of myocardium during cardiac
surgery (dogs, cats, human)
M R01HL19451-03 Functional characteristics of the left
heart
ROlHL-19451-03 0001 Functional characteristics of the
left heart - Ventricular performance using epicardial
radiopaque markers (human)
ROlHL-19451-03 0004 Functional characteristics of the
left heart - Quantitative coronary arteriography (human)
** ROlHL-19647-03 Therapeutic aerosols
R01HL1970403 Aerosol therapy (models, dogs, human)
** POlHL-19717-02 0046 Response of the lung to injury •
Bioengineering section
** R01HL19768-02 Recording and analysis of low levels
cardiac signals (human, dogs)
Gated imaging with the MGH x-ray
Bolus-response measurement of lung
Tissue analysis by mass spectrometer
Catheter ventricular defibrillation studies
Preservation of human platelets for
Intra-aortic balloon pumping (dogs.
36
• R01HL1979102 Ultrasonic monitoring visceral blood
vessels
' R01HL1997301 Non-Invasive sickled cell monitor
development (human)
' ROlHL-19975-02 Laryngeal biomechanics in pulmonary
therapy (primates)
' ROlHL-19993-02 Optical detection of platelet aggregates
(human, baboons)
ROlHL-20024-03 Therapeutic aerosols -Characteristics and
retention (human, dogs)
' ROlHL-20037-02 Left ventricular-aortic bypass and
composite prosthesis (sheep, swine, cattle)
' ROlHL-20077-02 External cardiac stimulation with
microwave radiation (dogs)
ROlHL-201 10-02 Microwave methods of lung water
measurement (dogs, phantom models)
• ROlHL-2019202 Ciliary activity of the lung studied by
laser scattering
ROlHL-2027402
camera
• ROlHL-20347-02
function (human)
• ROlHL-20351-02 A self-calibrating in vivo blood gas
monitor (dogs, infants)
' ROlHL-20356 02 Development and evaluation of an
artificial heart (calves)
ROlHL-2037403 Myocardial function -Risk (actors and
future CHD (human)
ROlHL-2054602 Chemical analysis of human arterial
elastin
ROlHL-20554-02 Memory-alloy-filters for venous emboli
(dogs)
POlHL-20592-02 0012 Cell biology of cardiac and
skeletal muscle - Contractile properties of skinned muscle
fibers (frogs)
ROlHL-20607-02
(dogs)
■ ROlHL-2062902
(dogs)
' ROlHL-2063003 Development of a pulsed Doppler velocity
detector (human, animals)
' ROlHL-20632-02 An optimal fetal heart monitor (human)
ROlHL-2067402 Evaluation of cardiac function with
radioactive tracers
ROlHL-207 16-02 Freezing and electromagnetic thawing of
platelets (rats)
■ ROlHL-20788-02
transfusion
' ROlHL-20803-02
lambs, cats)
ROlHL-20815-02 Validation of indirect tests of small
airways function (human, dogs, ponies)
' ROlHL-2083502 Signal analysis of turbulence study in
blood
ROlHL-20898-02 Ultrasonic evaluation in direct arterial
surgery (models, cattle, human)
ROlHL-20979-02 A novel pulsed Doppler flowmeter (dogs)
R23HL-21 168-01 Hypoxemic respiratory failure-Physiologic
evaluation (human, dogs)
R01HL-2I194-02 Development of antithrombogenic plastic
biomaterials
R23HL-2 11 99-02 Sound transmission in lung (dog)
R23HL-21271-02 Extracorporeal circulation and protein
denaturation (human)
ROlHL-21278-01 Abnormal cardiac wall motion viewed
ultrasonically (human, dogs, phantoms)
ROlHL-21444-02 Pulmonary mechanics during postnatal
development (human)
ROlHL-21674-01 Development of automatic implanted
defibrillator (dogs, cattle)
R01HL-21707-0I Quantification of infarct size by emission
tomography (human, dogs)
ROlHL-21751-02 0003 ThaHium and antimyosin in
ischemia and infarction ■ Human studies-Ischemia and
infarction
ROlHL-22005-01 Intermittent retroperfusion of ischemic
myocardium (dogs)
ROlHL-22032-01 Cardiovascular events in hypertensives
(human)
ROlHL-2208001 Phosphorus NMR studies on cardiac
tissue (rats, rabbits)
ROlHL-2228101 Microprobe analysis and metabolite
levels of ischemic mycardium (dogs)
ROlHL-223 15-01 Intraoperative cardiac oxygen supply-
demand (dogs, rabbits, rats)
ROlHL-22321-01 Cardiac output from the
pneumocardiogram (dogs)
ROlHL-22326-01 Noninvasive measurement of cardiac
output (dogs)
ROlHL-22338-01 Platelet adhesion and aggregation in a
flow chamber (human)
R23HL-2234601 Hematological injury and pulmonary
dysfunction (human, mammals)
ROlHL-22417-01 Microprocessors in medical applications
(dogs)
ROlHL-2251201 Ultrasonic instrumentation for
cardiovascular studies
ROIHL 22517-01 Engineering development of an ultrasonic
ventilometer (human)
R01HL-2260401 Non-invasive system for arteriosclerosis
studies (human)
BIO
ROlHL-22636-01 Newborn lung function during
mechanical ventilation (human)
ROlHL-22661-01 Chronic total cardiopulhonary mechanical
substitution (sheep)
ROlHL-22699-01 Defibrillation electrode studies (dogs,
swine)
ROlHL-22809-01 Coronary-prone behavior and
cardiovascular reactivity (human)
ROlHL-2284401 Phrenic nerve pacing-Noninvasive
diaphragm analysis (human, dogs)
ROlHL-22854-01 Non-invasive blood pressure
measurement (rats)
ROlHL-22888-01 Prosthetic valve endocarditis-Etiology
and therapy (dogs)
P60HL-23282-01 0001 Comprehensive hospital/community
sickle cell center • Fetoscopy for intrauterine diagnosis of
hemoglobinopathy (human, monkeys)
ROlHL-23983-01 Quantitative radiocardiography (human.
dogs)
NOlHR-32900-09 Pilot study to standardize the
measurement of 'closing volume' (human)
NOlHR-6290104 Measure pulmonary function in infants
and children (also dogs, rabbits)
NOlHR-62920-02 Noninvasive diagnosis of pulmonary
hypertension (dog, human)
N01HV12065-16 Fabrication of implantable artificial heart
devices (animals)
NOlHV-42914-13 Solenoid left ventricular assist system
(cattle)
NOlHV-42960-07 Development and evaluation of cardiac
prostheses (calves)
NOlHV-52966-01 Development and evaluation of an
ultrasonic imaging system (swine)
NOlHV-53008-07 Left ventricular assist device-Clinical
evaluation (human)
NOlHV-72918-01
devices
N01HV-72919-01
Test polymers for circulatory assist
Test polymers for circulatory assist
Left heart assist blood pumps (calves)
Development of a left heart assist blood
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
•*Onented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number
divices
NOlHV-7292404 Noninvasive detection of atherosclerotic
lesions (human, animals)
NOlHV-72925-04 Non-invasive detection of atherosclerotic
lesions (human, monkeys, dogs)
•* NOlHV-7292604 Ultrasonic imaging development
** NOlHV-72927-00 Systems for non-invasive detection of
atherosclerotic lesions (human)
** NOlHV-72928-04 Develop high resolution ultrasonic
imaging techniques
NOlHV-72929-01 Improved detection of atherosclerosis
(human, dogs)
NOlHV-72930-02 Atherosclerosis assessment-Angiography
and ultrasound (dogs, human)
NOlHV-72931-02 Non-invasive detection of atherosclerotic
lesions (human, dogs)
NOlHV-7293200 Noninvasive detection of atherosclerotic
lesions (human, phantoms)
** NOlHV-72933-01 Electrical energy transmission technique
development (dogs)
" NOlHV-7293401 Development of a left heart assist blood
pumps (human, cattle)
** NOlHV-72936-00 Left heart assist device development
(human, cattle)
** NOlHV-72937-00
** NOlHV-72938-01
pump
" NOlHV-72939-01 Develop and evaluate left heart assist
blood pumps (human, calves, pigs)
** NOlHV-72971-01 Energy converters to control heart assist
devices (human, cattle)
" NOlHV-72975-02 Energy converter for left ventrical assist
devices (calves)
** NOlHV-72976-02 Energy converters to control heart assist
devices (human, cattle)
NOlHV-81388-20 Microfiber substrate for growth of intimal
linings in circulatory assist devices
** NOlHV-82919-00 Development of percutaneous energy
transmission systems
BIOMEDICAL ENGINEERING, INSTRUMENTATION
NOT CLINICALLY ORIENTED
ROlHL-01015-27 Hypertension and left ventricular
hypertrophy (dogs)
ROlHL-02493-22 Kidney function in experimental heart
failure (dogs, rats)
POlHL-06285-18 0198 Cardiovascular-respiratory
physiology and biochemistry - Renal tubular secretion of
hydrogen ion (animals)
POlHL-06296-18 0002 Cardiovascular and pulmonary
adaptation to stress - Respiratory muscle blood flow.
mechanics and metabolism (human, dog)
POlHL-06314-17 0050 Immunologic mechanisms in
cardiovascular disease - Physiologic changes in
lymphocytes (human, mice)
POlHL-07896-15 0045 Environmental biomedical research
program - Extravascular lung water dynamics in pulmonary
oxygen toxicity (human, baboons)
** POlHL-08214-15 0006 Chemical and biological properties
of lipids - Analysis and properties of lipids
POlHL-08214-15 0040 Chemical and biological properties
of lipids - Nuclear magnetic resonance studies of lipids
** P01HL08214-15 0047 Chemical and biological properties
of lipids ■ High resolution liquid chromatography for the
analysis of biological substances
(contd)
^£S
BIO
•* POIHI 08805 15 0043 Rtgulslion ot venlilstioii »nd
pulmonsry citciilation Compulef core tjcility
ROIHI 089/; 14 Quanlitatioii o( flow and solute tlui in
miciovessels (cats, lats)
POIHI 09011 15 00?? A lesearch and resource program
in blood Cryopreservation ol blood components (human)
ROIHI 10330 11 Physiological mechanics ol the heart and
arteries (dogs, rabbits, horses)
ROIHI 11153 1? Quantitation ol How and solute llu> in
microvessels (cats, rats)
POIHI 11307 1? 000? Biophysical studies in pediatric
cardiology Cardiac eitracellulai electiophysioiogy (human.
dog, chimpaniee)
POIHL 11351 12 0018 Cellular and molecular
mechanisms ol myocardial function Quantitative
localization of electrolytes in cardiac tissue
POIHL 11351 1? 0019 Cellular and molecular
mechanisms ot myocardial function Mechano chemical
kinetics ol small perturbations
"* POIHL 11678 11 9003 Cardiovascular dynamics and their
control Core Instrumentation and machine shop
•' ROIHL 11822 10 Biophysical studies of macromolecular
interactions (microorganism, human)
ROIHL 1252810 NMR relaxation of liquid crystal systems
ROIHI 13399 16 Heme protein structure and function
(human, horse, plants, bacteria)
PO1HL1373707 0037 Assisted circulation Clinical
measurement of blood flow through aortocoronary vein
bypass graft
P50HL 14147-08 0015 Specialized center of research in
thrombosis ■ Charge related properties ot phospholipid
surfaces in monolayers and vesicles
P50HL15092-07 0001 Immune and fibrotic response to
occupational environments ■ X-ray diffraction study-Dust
exposure in asbestos cement products manufacturing
P50HL-15092-07 0010 Immune and fibrotic response to
occupational environments - Characterization of toluene
diisocyanate in industrial environments
POlHL-15194-07 9003 Pathophysiology of
cardiopulmonary dysfunction ■ Electronics laboratory core
ROlHL-15740-06 In vitro studies on heart cell function
(rats)
P60HL1600806 0017 Wayne State University
comprehensive sickle cell center - Oxygen transport kinetics
of pre- and post-sickling cells (human)
POlHL-16607-05 0006 Calcium ion and control of
cardiovascular function Sarcomere and contractile
dynamics of striated muscle cells (animals)
ROlHL-16828-04 Gradient and transport of oxygen in
tissue and organs (mammals)
POlHL-16833-04 0003 Hemoglobin and red cell system in
hemoglobinopathies - Oxygen binding curves and equilibria
(human)
POlHL-16833-04 0008 Hemoglobin and red cell system in
hemoglobinopathies - Membrane associated phenomena in
SS disease
POlHL-16833-04 0015 Hemoglobin and red cell system in
hemoglobinopathies - Stereochemistry of hemoglobins from
magnetic circular dichroism (human)
R01HL-16855-03 Cavitation in biological systems
(microorganisms, animals)
** P60HL-17269-04 0016 National heart and blood vessel
research and demonstration center - New analytical
methodology for atherosclerosis studies
•* POlHL-18208-04 00C2 Center for the study of blood cell
rheology - Holography of RBC shape (human)
P01HL-18574-C3 0001 Lipoprotein methodology and
biomedical applications - Ulfracentrifugal and
electrophoretic lipoprotein methodology-Applications
POlHL-18576-03 0010 Thrombosis research program
project - Evaluation of non-thrombogenic materials (cattle)
POlHL-18576-03 0015 Thrombosis research program
project ■ Major equipment core
R01HL-18676-C3 Myocardial sarcomere mechanics (rat)
ROlHL-18831-03 Microscopy of spontaneously hypertensive
arterial lesion (rats)
R01HL18952-03 Metabolism in. perfused fetal and
newborn rabbit lungs
POlHL-19259-03 0006 Digoxin-specific antibody in human
therapy - Core
** ROlHL-19481-03 High-field NMR studies of respiratory
proteins (human, horse, fish, microbes)
ROlHL-19715-02 Respiratory tract deposition of
hygroscopic aerosols (dogs, human)
POlHL-19737-02 0012 Cellular and molecular aspects of
respiratory physiology - Mass spectrometer facility
** ROlHL-19848-02 Contractile activation by rapid
temperature jumps (frogs)
** ROlHL-20354-02 Direct determination of oxygen tension in
the clinical environment (human, dogs)
♦* POlHL-20592-02 0003 Cell biology of cardiac and
skeletal muscle - Cellular magnesium and anion activities
in ion-specific microelectrodes (frogs)
P01HL-210I6-02 CC18 Sickle cell anemia and other
hemoglobinopathies - Scanning and transmission electron
microscopy
ROlHL-21371-02 Energy loss microanalysis of myocardial
cations
** P01HL-22163-CI 0002 Surface thrombogenesis-
Mechanisms and prevention - Laser-scattering detection of
microemboli in blood flow (baboons)
37
ROIHI 77??3 01 The cardio pulmonary lunction (do|>.
niudelsl
** ROIHI ???33 01 Characterizntmn ol bio materials by
elastic property
ROIHI ??3?5 01 Thermodynamics in respiratory protein
binding (human trout)
ROIHI ??91/ 01 Miciovasculai picssures in the intact
beating heart (rabbits)
R?3Hl ??9?0 01 Dynamic airway behavior (dogs)
ROIHI ?3?G7 01 Rheology and kinetics of hemoglobin S
Relation (human)
BIOMEDICAL ENGINEERING, MEDICAL
EQUIPMENT SAFETY
ROIHL 0466b 19 Artificially paced hearts- Technology,
physiology (human, dogs)
** ROIHL 15247 05 Extending the life of implanted
pacemakers (dogs, human)
P60HL 17269 04 0030 National heart and blood vessel
research and demonstration center Cardiovascular
engineering laboratories (human)
** ROIHL 1997502 Laryngeal biomechanics in pulmonary
therapy (primates)
ROIHL 2007702 External cardiac stimulation with
microwave radiation (dogs)
** ROIHL 20803 02 Intra aortic balloon pumping (dogs.
lambs, cats)
** ROIHL 22699 01 Defibrillation electrode studies (dogs,
swine)
NOIHV 42914 13 Solenoid left ventricular assist system
(cattle)
BIOMEDICAL FACILITIES
SEE ALSO ANIMAL FACILITIES, RESOURCES
SEE ALSO BIOMEDICAL SYSTEMS AUTOMATED
SEE ALSO HEALTH CARE FACILITIES (GENERAL)
POIHL 04664 18 0005 Cardiovascular and lung dynamics
Applications of current research, equipment and
techniques
POIHL 04664-18 0011 Cardiovascular and lung dynamics
- Detection of abnormal segments of the human ventricle
by measure of asynergy
POlHL-04664-18 0015 Cardiovascular and lung dynamics
■ Computer system for the cardiovascular laboratory
P01HL06350-I7 0018 Hemostasis research program
project - Varients of factors IX (human, cattle)
** POlHL-06664-17 0041 Cardiopulmonary function in
remediable vascular disease - Core facility for quantitative
microscopy
P01HL08805-15 0042 Regulation of ventilation and
pulmonary circulation - Electron microscope core research
laboratory
POlHL-08805-15 0043 Regulation of ventilation and
pulmonary circulation - Computer core facility
** POlHL-08974-14 9001 Natural and experimental
atherosclerosis - Core-Lipid chemistry laboratory
** POIHL-08974-14 9002 Natural and experimental
atherosclerosis - Core-Histology and histochemistry
laboratory
** POlHL-10342-13 9001 The integrated function of
respiration and circulation ■ Technical core
** PClHL-11307 12 9001 Biophysical studies in pediatric
caidiology - Core support-computer science
** POlHL-1 1307-12 9002 Biophysical studies in pediatric
cardiology - Biomedical engineering
** POlHL-11310-12 9001 Mechanisms of cardiovascular
disease - Core support-hospital beds
** POlHL-11310-12 9002 Mechanisms of cardiovascular
disease - Core support-centralized electronic laboratory
** POlHL-11310-12 9003 Mechanisms of cardiovascular
disease - Core support-biophysical sciences
** POlHL-11310-12 9004 Mechanisms of cardiovascular
disease - Core support-computer facilities
** POlHL-11678-11 9001 Cardiovascular dynamics and their
control - Core-Computer services
** POlHL-1 1678-11 9002 Cardiovascular dynamics and their
control - Core-Radioimmunoassay and chemical laboratory
** POlHL-11678-11 9003 Cardiovascular dynamics and their
control ■ Core -Instrumentation and machine shop
** POlHL-12373-10 0014 Cardiopulmonary physiology and
pathophysiology - Analog digital computation and
simulation facility
POlHL-12373-10 0015 Cardiopulmonary physiology and
pathophysiology - Cine angiographic-hemodynamic facility
POIHL-12373-10 0016 Cardiopulmonary physiology and
pathophysiology - Histology-histochemistry-Gough laboratory
** POlHL-12373-10 0018 Cardiopulmonary physiology and
pathophysiology Biochemistry laboratory
POlHL-12373-10 0019 Cardiopulmonary physiology and
pathophysiology - Free ranging animal facility
** POIHL 12373-10 0020 Cardiopulmonary physiology and
pathophysiology - Hospitalization and patient care
POlHL-13330-08 0062 Mechanical circulatory support -
CORE facilities
ROlHL-13881-08 The American Red Cross National
Fractionation Center
*' ROlHL-13885-08 9001 Cystic fibrosis and pulmonary
disease - Pulmonary function core facility (infants,
children)
** ROlHL-13885-08 9002 Cystic fibrosis and pulmonary
disease - Computer core facility (human)
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level
"•Oriented significantly to above subject
M Grant has subprojects describing specific
See AppendiK for investigator's name and gr
BIO
•• ROIHI 13885 08 9003 Cystic librov. and pulmonary
diKise Fiberoptic bronchoscopy core licilrly (human,
dogs, sheep)
ROIHI 13974 0/ Vtnlriculir premitur* txalt and luddtn
coronary death (human)
P50HI 14136 07 900? Pulmonary SCOR Airway,
obstructive diseases Physiology core (human animal)
*• P50HI 14136 07 9003 Pulmonary SCOR Airway,
obstructive diseases Pathology core (human, dogs)
P50HI 14136 07 9004 Pulmonary SCOR Airway,
obstructive dr.eases Radiology core (human)
*• P50HI 141160/ 9007 Pulmonary SCOR Airway,
obstructive diseases Special Isi.ililie', core
P50HI 14138 05 0014 Center lor re'.earch on
atherosclerosis Core biostatislic, laboratory
** P50HI I4I47 08 0016 Specialized center of research in
thrombosis Nuclear medicine core laboratory (human,
dogs, rats, rabbits)
•* PbOni 14147 08 0017 Specialized center ol research in
thrombosis Core coagulation laboratory (human)
** P50HL 14153 07 0018 lohns Hopkins lung Center
Chronic diseases of airways Pulmonary function core
** P50HI 14153 07 0019 lohns Hopkins lung Center
Chronic diseases of airways Pathology core (human,
animal)
** P50HL 14159 08 0022 Specialized center of research in
hypertension Core laboratory
** P50HL 14159 08 0023 Specialized center of research in
hypertension Core computation
** P50HL 14159 08 0024 Specialized center of research in
hypertension Core resources (clinical, animal models)
•• P50HL 14164 07 0026 A/S SCOR Comparative and
experimental atherosclerosis Comparative pathology unit
(pigeons, monkeys)
** P50HL 14164 07 0034 A/S SCOR Comparative and
experimental atherosclerosis Core lipid analytic laboratory
** P50HL 14164-07 0039 A/S SCOR -Comparative and
experimental atherosclerosis Statistical resource and
research management unit
** P50HL-14164-07 0040 A/S SCOR Comparative and
experimental atherosclerosis Core angiochemistry
laboratory
** P50HL 14164-07 0042 A/S SCOR -Comparative and
experimental atherosclerosis Comparative cardiology
laboratory (monkeys)
" P50HL 14164-07 0043 A/S SCOR -Comparative and
experimental atherosclerosis - Electron microscopy resource
laboratory
** P50HL-14187-07 0016 Pulmonary SCOR -Chemical
mediators in pulmonary vascular responses - Core
pathology service (dogs, rabbits, human)
" P50HL-14197-07 0008 Support for center of research on
arteriosclerosis - Core facility -Lipoprotein preparation,
immunochemistry
** P50HL-14214 07 0037 Newborn lung center for hyaline
membrane disease - Core -Histopafhology laboratories
** P50HL-14217-08 0063 Specialized center of research in
thrombosis - Special clinical studies laboratory
** P50HL 14230 07 9001 A/S SCOR Lipids, atherosclerosis
and thrombosis Core lipid laboratory
*♦ P50HL-14230-07 9002 A/S SCOR -Lipids, atherosclerosis
and thrombosis - Core tissue culture laboratory
** P50HL-14237-07 0007 Support for arteriosclerosis center
- Core laboratories
M POlHL-1438807 Regulation of the circulation in
pathological states
** POlHL-1438807 9001 Regulation of the circulation in
pathological states - Core facility for hypertensive animal
colony (rats)
** POIHL 14388-07 9002 Regulation of the circulation in
pathological states - Core immunoassay laboratory (rabbits)
** POlHL-14388-07 9003 Regulation of the circulation in
pathological states - Electron probe projects
" POlHL-14388-07 9004 Regulation of the circulation in
pathological states - Core biostatistics unit
** POlHL-14388 07 9005 Regulation of the circulation in
pathological states - Core administration
** POlHL-14414-07 9001 Environmental influences on
cardiorespiratory and cellular functions ■ Laboratory core
facility
** POlHL-14414-07 9002 Environmental influences on
cardiorespiratory and cellular functions - Core -Computer
facility
** POlHL-14414-07 9003 Environmental influences on
cardiorespiratory and cellular functions - Machine and
electronics shop -Core facility
" P50HL-15O62-07 0021 Study of lipoproteins, artery wall.
and atherosclerosis - Core laboratories
** P50HL-15092-07 0013 Immune and fibrotic response to
occupational environments - Epidemiology core resource
** P50HL-15092 07 0014 Immune and fibrotic response to
occupational environments Clinical immunology core
resource
P60HL-15158-07 00C4 Comprehensive sickle cell center ■
Expression of abnormal hemoglobin synthesis in the
neonate and young child
** P60HL-15160-07 0012 Center for sickle cell disease -
Core laboratories
" POlHL-15194-07 9001 Pathophysiology of
cardiopulmonary dysfunction - Analytical laboratory core
(contd)
research aspects,
ant number
P01HL16851-04 0010
health and disease -
P01HL16851-04 0011
health and disease -
P0IHL16851-04 0012
health and disease -
P01HL16878-05 0005
BIO
POlHL-15194-07 9002 Pathophysiology of
cardiopulmonary dysfunction - Data piocessing laboratory
core
** P01HL15194-07 9003 Pathophysiology of
cardiopulmonary dysfunction - Electronics laboratory core
POlHL-15265-05 0004 Program on surgical control of the
hyperlipidemias • Coordinating center and central data
processing facility
** P50HL-15389-07 0016 Pulmonary SCOR-Hypersensitivity
pneumonitis - Pulmonary physiology core (human)
** P50HL1538907 0017 Pulmonary SCOR-Hypersensitivity
pneumonitis - Immunology core (human)
** P50HL15389-07 0018 Pulmonary SCOR-Hypersensitivity
pneumonitis - Pathology core (human, animal)
** P50HL-15389-07 0019 Pulmonary SCOR-Hypersensitivity
pneumonitis - Microbiology core (human, animal)
** P01HL.1583206 9001 Chemical-structural predispositions
to lung injury Tissue culture studies of lung cell function-
Core facility
** POlHL-1583506 0027 Study of muscles related to heart
disease - Core ll-lntermediate voltage EM of muscle
** P6OHL-160O5-O5 9001 Comprehensive sickle cell center -
Core laboratory and counseling (human)
*• POlHL-16769-05 0009 Pathobiologic and host defense
reactions in the lung - Electron microscopy and tissue
culture core laboratory
POlHl-16769-05 0011 Pathobiologic and host defense
reactions in the lung ■ Core -Laboratory for biomedical
preparation (rabbits)
M POlHL-16851-04 Human red cell membrane in health and
disease
Human red cell membrane in
Core facility -Hematology clinic
Human red cell membrane in
Ultrastructure laboratory-Core facility
Human red cell membrane in
Computer unit-Core facility
Control of ventilation in health
and disease - Program core
P60HL- 17269-04 0004 National heart and blood vessel
research and demonstration center - Atherosclerosis -
Clinical surgical aspects (human)
P60HL-17269-04 0027 National heart and blood vessel
research and demonstration center - Non-invasive
evaluation of cardiac functlon-lschemic heart disease
(human, dog)
** POIHL- 1742 1-05 0006 Regulation and exchange in the
microcirculation - Core facilities -Optical instrumentation
facility
** P50HL-1 7646-04 0001 Study of ischemic heart disease -
Core clinical investigation unit
** P50HL- 17646-04 0002 Study of ischemic heart disease -
Core data management
** P50HL-1 7646-04 0003 Study of ischemic heart disease -
Core pathology facility (human, dogs)
** P50HL-17646-04 0004 Study of ischemic heart disease -
Core experimental animal laboratories
** P50HL-17648-04 0020 Study of ischemic heart disease -
Core pathology laboratory-lschemic heart disease (human,
animal)
M P50HL-17651-04 Ischemic heart disease specialized center
of research
P50HL-1 7651-04 0032 Ischemic heart disease specialized
center of research - Cardiovascular surgery core (human,
dogs)
** P50HL-17651-04 0033
center of research
" P50HL-17651-04 0035
center of research
biophysics
** P50HL-17651-04 0036 Ischemic heart disease specialized
center of research - Core facilities -Cardiovascular
pathology (human, dog)
P50HL-1 7651-04 0046 Ischemic heart disease specialized
center of research - Clinical core-Physiological
changes/biochemical effects of myocardial ischemia
P50HL-17651-04 0047 Ischemic heart disease specialized
center of research - Clinical core-Automated arrhythmia
monitoring system
** P50HL-1 7655-04 0010 Study of ischemic heart disease -
Core facility -Cardiovascular pathology (human, animal)
** P50HL-17655-04 0011 Study of ischemic heart disease -
Core facility -Cardiovascular nuclear medicine (human, dog)
** P50HL-17665-04 0008 Study of ischemic heart disease -
Core laboratory-CPK isoenzyme measurement and
myocardial necrosis evaluation
Ischemic heart disease specialized
Core facilities -Computer sciences
Ischemic heart disease specialized
Core facilities-Biomedical engineering,
Study of ischemic heart disease
Study of ischemic heart disease
P50HL-1 7665-04 0030
Data management
P50HL-1 7667-04 0038
Clinical core unit
P50HL-17667-04 0039 Study of ischemic heart disease -
Core human investigative laboratories
P50HL-1 7667-04 0040 Study of ischemic heart disease -
Core biochemistry-Cardiac metabolism (human)
P50HL 17667-04 0041 Study of ischemic heart disease -
Biophysical sciences core-Data collection and retrieval
P50HL-1 7667-04 0042 Study of ischemic heart disease -
Core-Central instrumentation and software
P50HL-1 7667-04 0044 Study of ischemic heart disease -
Core-Data management and analysis
P50HL- 17670-04 0016 Study of ischemic heart disease -
Core pathology laboratory (human, dogs, monkeys)
Study of ischemic heart disease
Study of ischemic heart disease
38
P50HL-17670-04 0017 Study of ischemic heart disease
Core enzymology laboratory (human)
P50HL-17670-04 0018 Study of ischemic heart disease ■
Core electrocardiogram laboratory (human)
P50HL- 17682-04 0008
Clinical core unit
P50HL-17682-04 0009
Computer core unit
P50HL- 17682-04 0010 Study of ischemic heart disease -
Core clinical enzyme laboratory (human, mice, dogs, rats)
P50HL-17682-04 0011 Study of ischemic heart disease -
Nuclear medicine core unit (human, dogs, rabbits, mice)
P50HL-17682-04 0012 Study of ischemic heart disease -
Pathology core laboratory (human)
P50HL-1 7682-04 0023 Study of ischemic heart disease -
Core cell and organ culture laboratory (mice)
P50HL-183 18-03 0001 Pathogenesis and complications of
hypertension - Core clinical program
P50HL-18318-03 0002 Pathogenesis and complications of
hypertension - Core experimental animal facility (rats.
rabbits)
P50HL-18318-03 0003 Pathogenesis and complications of
hypertension - Core biochemical laboratory
P50HL-18323-04 0033 SCOR hypertension center - Core
laboratory-Renin, aldosterone and bradykinin methodology
P50HL 18323-04 0034 SCOR hypertension center - Core-
Data management
POlHL-18575-03 0011 Mechanisms of vascular changes
in hypertension - Chemistry laboratory core facility
POlHL-18575-03 0012 Mechanisms of vascular changes
in hypertension - Anatomy core facility
POlHL-18575-03 0013 Mechanisms of vascular changes
in hypertension - Biosfatistical core
POlHl-18576-03 0014 Thrombosis research program
project - Immunology core
POlHL-18576-03 0015 Thrombosis research program
project - Major equipment core
POlHL-18576-03 0016 Thrombosis research program
project - Radiochemistry core
POlHL-18577-03 0008 Lipoproteins-Cell surface
interactions - Core laboratory 1
POIHL 18577-03 0011 Lipoproteins-Cell surface
interactions Core laboratory 4
POlHL-18708-03 0008 Oxygen, energy and contractility in
cardiac tissue - Cardiac cell culture facility
POIHL- 189 74-03 0014 Experimental neurogenic
hypertension program - Administrative core
Experimental neurogenic
Neurochemistry core
Experimental neurogenic
Neuroanatomy core
Experimental neurogenic
Computer-physiology core
SCOR-Pulmonary edemas-Eitology,
* POlHL-18974-03 0015
hypertension program
' POlHL-18974-03 0016
hypertension program
' POlHL-18974-03 0017
hypertension program
• P50HL-191 53-02 0007
pathogenesis - Core-Experimental laboratories and support
facilities
' P50HL-191 53-02 0008 SCOR-Pulmonaiy edemas-Eitology,
pathogenesis - Core -Biomedical engineering
' P50HL-191 55-02 0008 Pathophysiology of pulmonary
edema - Core microscopy laboratory
' P50HL-19156-02 0006 Pulmonary SCOR -Chronic diseases
of airways - Core microscopy laboratory
■ P50HL-191 57-02 0001 Studies in cystic fibrosis and
bronchiolitis - Laboratory core unit
' P50HL-19157-02 0002 Studies in cystic fibrosis and
bronchiolitis - Clinical core
' P50HL-191 70-02 0010 Harvard pulmonary SCOR -Chronic
diseases of the airways - Computer Core
' P50HL-191 71-02 0012 Pulmonary SCOR -Lung injury by
childhood infections - Laboratory support core
' P50HL-191 85-02 0012 Pulmonary SCOR -Neonatal
respiratory distress syndromes - Core microscopy lab
P50HL-19187-02 0013 Pediatric pulmonary SCOR-Hyaline
membrane disease - Research resources core
P50HL-191 90-02 0001 Pulmonary SCOR -Pathophysiology,
management of IRDS - Core-Clinical research center
(infants)
P50HL-19 190-02 0002
management of IRDS
dissemination
POIHL- 192 59-03 0006
therapy - Core
P50HL-19362-02 0013 A/SSCOR-Atherosclerosis in
nonhuman primates - Core laboratory-Lipid biochemistry
(baboons)
P50HL-19362-02 0014 A/S SCOR -Atherosclerosis in
nonhuman primates - Core laboratory-Behavior observation
and manipulation (baboon)
P50HL-19362-02 0015 A/S SCOR -Atherosclerosis in
nonhuman primates - Core laboratory-Pathology and
morphometry (baboons)
P50HL- 193 62-02 0016 A/S SCOR -Atherosclerosis in
nonhuman primates - Core laboratory-Animal services
Pulmonary SCOR -Pathophysiology,
Core-Demonstration and
Digoxin-specific antibody in human
(baboon)
P50HL-19362-02 0017
nonhuman primates -
statistical analysis
POlHL-19737-02 0012
res|>iratory physiology
POlHL-19737-02 0013
respiratory physiology
A/S SCOR -Atherosclerosis in
Core laboratory -Data management.
Cellular and molecular aspects of
- Mass spectrometer facility
Cellular and molecular aspects of
- Cell metabolism analytical facility
BIO
POlHL-19737-02 0014 Cellular and molecular aspects of
respiratory physiology - Cell separation facility
POlHL-20552-02 9001 The development and regression of
cardiac hypertrophy - Core A-Pathology
POlHL-20552-02 9003 The development and regression of
cardiac hypertrophy - Core D-Amino acids analysis
POlHL-20581-01 9001 Vascular neuroeffector
mechanisms in health and disease - Morphology core
POlHL-20581 01 9002 Vascular neuroeffector
mechanisms in health and disease - Biochemistry core
POlHL-20592-02 0014 Cell biology of cardiac and
skeletal muscle - Core laboratory
POlHL-20948-02 9001 Molecular basis of cholesterol
metabolism - Tissue culture core laboratory
POIHL 20948-02 9002 Molecular basis of cholesterol
metabolism - Microscopy core laboratory
POlHL-20984-02 Cellular mechanisms in cardiac
hypertrophy
POlHL-20984-02 9001 Cellular mechanisms in cardiac
hypertrophy - Animal models and preparation of contractile
proteins
POlHL-20984-02 9002 Cellular mechanisms in cardiac
hypertrophy - The heart in organ culture
POlHL-20993-02 0011 Population dynamics of arterial
cells in atherogenesis - Light and electron microscopy
laboratories-Core
POlHL-20993-02 0012 Population dynamics of arterial
cells in atherogenesis - Chemistry laboratory -Core
POIHL-20994-02 Dynamics of neutrophil elastase in the
lung
POlHL-20994-02 9001 Dynamics of neutrophil elastase in
the lung - Biochemistry and immunology core
POlHL-20994-02 9002 Dynamics of neutrophil elastase in
the lung - Ultrastructural core
POIHL 20994-02 9003 Dynamics of neutrophil elastase in
the lung - Autoradiography-Histology core
POlHL-2 1016-02 0018 Sickle cell anemia and other
hemoglobinopathies - Scanning and transmission electron
microscopy
POlHL-2 1584-02 9001 Respiratory mechanics in normal
and abnormal states - Technical and equipment core
ROlHL-2 1684-02 0003 Radionuclide infarct sizing and
therapy evaluation - Core pathology laboratory (dogs,
human)
POlHL-22163-01 9001 Surface thrombogenesis-
Mechanisms and prevention - Polymers for studing blood-
material interactions core
POlHL-22602-01 9001 Pathophysiology of the
endothelium - Morphology core
POlHL-22602-01 9002 Pathophysiology of the
endothelium - Core -Culture of blood vessel-Derived cells
POlHL-22619-01 9001 Cellular mechanisms of heart
failure - Experimental pathological models core
POlHL-22619-01 9002 Cellular mechanisms of heart
fail
POlHl-22619-01 9003 Cellular mechanisms of heart
failure - Computer facility core
P01HLt»J63MUj(Mi|lcheml6l#utofda(HhlW(eimtetM)lflgy of
lipoprotein metabolism - Tissue culture core
POlHL-22633-01 9002 Cellular and molecular biology of
lipoprotein metabolism - Lipoprotein laboratory core
P60HL-23282-01 Comprehensive hospital/community sickle
cell center
P60HL-23282-01 9001 Comprehensive hospital/community
sickle cell center - Core-lnstitutionalization of education,
screening and counseling
P60HL-23282-01 9002 Comprehensive hospital/community
sickle cell center - Core-Model sickle cell service for
neighborhood health centers
NOlHR-62930-03 Lung cell resource facility
Modification of silicon elastomers for
NOlHV-32949-11
medical devices
N01HV-72950-02
trial
Central laboratory for propranolol heart
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level
•*Oriented significantly to above subject-
M Grant has subprojects describing specific research aspects.
See Appendix for investieator's name and grant number
BIOMEDICAL MANPOWER
SEE HEALTH SCIENCES PROFESSIONS, HEALTH SCIENCES
MANPOWER
BIOMEDICAL REGISTRIES AND REFERRAL
CENTERS
SEE ALSO BLOOD PRESERVATION. BLOOD BANKS, CENTERS-
RESOURCES-REGISTRIES
SEE ALSO CHEMICAL AND DRUG REGISTRIES, REFERRAL
CENTERS AND RESOURCES
SEE ALSO GENETIC REGISTRIES AND REFERRAL CENTERS
SEE ALSO HEALTH RECORD SYSTEMS, PATIENT (DISEASE)
REGISTRIES
SEE ALSO HEALTH SCIENCES PROFESSIONS, HEALTH
SCIENCES MANPOWER DATA AND REGISTRIES
SEE ALSO TISSUE (CELL) CULTURE, CELL CULTURE
COLLECTIONS BANKS AND REGISTRIES
SEE ALSO TISSUE COMPATIBILITY-TRANSPLANTATION
RESOURCES, REFERRAL CENTERS AND
REGISTRIES
SEE ALSO TISSUE RESOURCES, REGISTRIES
ROlHL-04651-19 Remote stimulation by radio-frequency
transmission (dogs, human)
M POlHL-04664-18 Cardiovascular and lung dynamics
POlHL-08899-14 0072 Tolerance to respiratory gases in
health and disease - Inert gas exchange isobaric gas
counterdiffusion and decompression
(csntd)
■lO
801HI 10&I2 12 Thrombojis ind htmostisis AntlYJii,
mtthodi «nd ilindicdi (human, cattlt. venom)
•* PSOHl 14164 07 0039 US SCOR Compilative ind
aipeiimtntal atharoscltrasit Statiitical rasourct and
lesaaich mana|«mant unit
** P60HL 15158 07 0008 Compuhanjive sickle cell centei
Con lalraiatory ol tlie centei
P60HL 1726904 0004 National heart and blood vessel
rtstaich and demonstiation centei Atheioscleiosis
Clinical surgical aspects (human)
P60HL 17292 04 0023 Veimont Lunt Centei Health
inhumation lesouices
POIHI 18575 03 0013 Mechanisms ol visculai changes
in hypertension Biostatistical coie
*• NOIHV 53010 03 NAS NRC twin tegistry
BIOMEDICAL RESEARCH
SFf HEALIH SCIENCFS RESEARCH (GENERAL)*
BIOMEDICAL RESEARCH-EVAIUATION-
PLANNING
SEE HEALTH SCIENCES RESEARCH ANALYSIS EVALUATION
PUNNING
BIOMEDICAL RESOURCES (GENERAL)
SEE ALSO ANIMAL FACILITIES, RESOURCES
SEE ALSO BIOLOGICAL PREPARATIONS AND STANDARDIZATION
SEE ALSO BLOOD PRESERVATION. BLOOD BANKS. CENTERS
RESOURCES REGISTRIES
SEE ALSO CHEMICAL AND DRUG REGISTRIES. REFERRAL
CENTERS AND RESOURCES
SEE ALSO IMMUNOLOGICAL PREPARATIONS
(GENERAUdNCLUOING CERTIFICATION AND
STANDARDIZATION)
SEE ALSO TISSUE (CELL) CULTURE, CELL CULTURE
COLLECTIONS BANKS AND REGISTRIES
SEE ALSO TISSUE RESOURCES, REGISTRIES
ROIHL 1088013 Purification ot human erythropoietin tor
research use
POIHL 13330 08 0062 Mechanical circulatoiv support
CORE facilities
ROIHL 13587 06 Synthesis of renin inhibitors and analog
phosphatides (rats)
P60HL15168-07 0001 Comprehensive sickle cell disease
center - Screening program (human)
R01HL1667505 Human urinary erythropoietin collection
POlHL-18708-03 0008 Oxygen, energy and contractility in
cardiac tissue - Cardiac cell culture facility
•* P01HL19717-02 0046 Response of the lung to injury ■
Bioengineering section
ROlHL-202 19-02 Cryopreservation of the isolated heart
(rats)
BIOMEDICAL SYSTEMS AUTOMATED
SEE ALSO COMPUTER (GENERAL) INCL COMPUTER DATA
PROCESSING (GENERAL)
SEE ALSO COMPUTER CENTERS
SEE ALSO HOSPITALS. INTENSIVE CARE UNITS
SEE ALSO OPTICS. IMAGE PROCESSING ANALYSIS AND
DISPLAY*
POlHL-0466418 0008 Cardiovascular and lung dynamics
■ Micrographic video imaging technique
P01HL0821415 0047 Chemical and biological properties
of lipids • High resolution liquid chromatography for the
analysis of biological substances
P01HL-0901M5 0017 A research and resource program
in blood • Operations research laboratory
** P01HL11310-12 0093 Mechanisms of cardiovascular
disease - Multiple dipole electrocardiogram project (human,
dogs)
POlHL-12373-10 0014 Cardiopulmonary physiology and
pathophysiology - Analog digital computation and
simulation facility
P50HL14138-05 0008 Center for research on
atherosclerosis - Core lipid laboratory (human)
P50HL1414105 0008 SCOR for atherosclerosis in
childhood - Core laboratory
*♦ P50HL-14236-05 0012 Prevention of premature
arteriosclerosis ■ Automated lipid analysis
** POlHL-15265-05 0003 Program on surgical control of the
hyperlipidemias ■ Central lipid laboratory
** P60HL-17269-04 0016 National heart and blood vessel
research and demonstration centei - Nev» analytical
methodology for atherosclerosis studies
ROlHL-20546-02 Chemical analysis of human arterial
elastin
ROlHL-20751-01 High speed liquid chromatography of
hemoglobins (human)
ROlHL-20788-02 Preservation of human platelets for
transfusion
BIOMEDICAL SYSTEMS AUTOMATED, COMPUTER
ASSISTED DIAGNOSIS
M POlHL-0466418 Cardiovascular and lung dynamics
P01HL-04664-18 0003 Cardiovascular and lung dynamics
■ X-ray projection image videometry (human, dogs)
POlHL-0466418 0005 Cardiovascular and lung dynamics
- Applications of current research, equipment and
techniques
POlHL-04664-18 0009 Cardiovascular and lung dynamics
- Biological signal and image processing techniques (dogs)
•* POlHL-04664-18 0010 Cardiovascular and lung dynamics
- Lett ventricular dynamics (human)
39
' POIHI 04664 18 0011 Caidiovasculai and lung dynamics
Detection ol abnormal jegmanls ol the human ventricle
by measure ot asyneigy
' POlHt 04664 18 0012 Cardiovascular and lung dynamics
Quantitative single plane lelt venlriculai angiogiaphy
(human)
' POIHI 04664 18 0013 Cardiovascular and lung dynamics
Ventriculai (unction in coionaiy disease using NTC and
ventiiculogiams (human)
' P01H104664 18 0014 Caidiovasculai and lung dynamics
Clinical application of computer analysis ol ventricular
wall motion
POIHL 04664 18 0015 Cardiovascular and lung dynamics
Computei system lor the cardiovascular laboiatory
POIHI 06308 18 0010 Mechanisms and therapy ol
circulatory disease Ventricular arrhythmias during exercise
to CHO and myocardial ischemia (human)
• R01H107575 15 Analysis ot time coherent cardiovascular
data
* POIHL 11678 11 0058 Cardiovascular dynamics and their
control Overall control of the circulation Computer
analysis
POIHL 12373 10 0014 Cardiopulmonary physiology and
pathophysiology Analog digital computation and
simulation facility
ROIHL 1397407 Ventricular premature beats and sudden
coronary death (human)
ROIHL 15016 07 New concepts in cardiac ultrasound
technology (human)
*• ROIHL 1504706 Digital computer analysis of the
electrocardiogram (human)
ROIHL 15191 07 Multiparameter methods for
cardiovascular research
POIHL 15265 05 0012 Program on surgical control of the
hyperlipidemias Central arteriography-Radiography
laboratory (human)
** R01HL16260-04 Development of clinical cine ultrasound
cardiography
•• ROlHL-16403 05 Prognostication by computer-Analyzed
vectorcardiogram (human)
ROlHL-16487-05 Computer controlled two dimensional
echocardiography
" ROlHL-1679103 Computer linkage for a dual camera
system
ROlHL-16901-05 Multipolar linkage between heart
geometry and surface (human, dogs)
ROlHL-16908-04 Myocardial function, risk factors and
future CHD (men)
ROlHL-16909-04 Myocardial function, risk factors and
future CHD (men)
** P60HL-17269-04 0026 National heart and blood vessel
research and demonstration center - Dynamics of ischemic
heart disease (human, dog)
P60HL-17269-04 0027 National heart and blood vessel
research and demonstration center - Non-invasive
evaluation of cardiac function-lschemic heart disease
(human, dog)
P60HL-1 7292-04 0031 Vermont Lung Center - Regional
respiratory computer network
P50HL-17646-04 0002 Study of ischemic heart disease -
Core data management
P50HL-17646-04 0010 Study ot ischemic heart disease -
Compliance in ischemic myocardium-Altered cardiac
performance (human, dogs)
** P50HL-17648-04 0006 Study of ischemic heart disease ■
Ventricular performance and myocardial perfusion in
obstructive coronary disease
** P50HL-1 7648-04 0033 Study of ischemic heart disease -
Data management-Electrocardiographic analysis system
** P50HL-17648-04 0034 Study of ischemic heart disease -
Data management-Hemodynamic data
P50HL-17651-04 0016 Ischemic heart disease specialized
center of research - Retropertusion of coronary venus
circulation with therapeutic agents (dogs)
P50HL-17651-04 0032 Ischemic heart disease specialized
center of research ■ Cardiovascular surgery core (human,
dogs)
P50HL-17651-04 0039 Ischemic heart disease specialized
center of research ■ Measurement and prediction of infarct
size (human, dog)
P50HL- 176 55-04 0011 Study of ischemic heart disease ■
Core facility-Cardiovascular nuclear medicine (human, dog)
** P50HL-17655-04 0012 Study of ischemic heart disease -
DATA management
** P50HL-17667-04 0029 Study of ischemic heart disease -
Computei diagnosis of cardiac arrhythmias after open
heart surgery (human)
** P50HL-17669-04 0013 Ischemic heart disease center
(SCOR) ■ Exercise in patients with ischemic heart disease
P50HL-17669-04 0023 Ischemic heart disease center
(SCOR) - Patients with acute myocardial infarction and
myocardial ischemia (human)
P50HL-17570-04 0008 Study of ischemic heart disease -
Surgical treatment of cardiac rhythm disorders (human,
dogs)
P50HL-17670-04 0014 Study of ischemic heart disease -
Real time ultrasound imaging in ischemic heart disease
(human, dog)
P50HL-17670-04 0018 Study of ischemic heart disease -
Core electrocardiogram laboratory (human)
** ROlHL-17931-04 Normalized body surface potential maps
(children)
■lO
ROIHI 18/6') 04 Studies in \uivivoit ot Itthil •iihylhmin
(human)
ROIHI 18/76 04 Prevention ot acuta and lata!
cardiovascular disease (human)
ROIHI 187H3 04 Detection and control ol venlriculai
premature beats (human)
ROlHt 18805 04 0001 Sudden cardnt dealh and Iht
onset ol myocardial infarction Predictive value ol
maximum exercise stiess testing (human)
ROIHI 18805 04 0005 Sudden caidiac death and the
onset ot myocaidial infaiction Sudden death suivivoii
Radionuclide studies (human)
M ROIHL 18808 04 Piediclion and piewention of sudden
caidiac death
ROIHL 18808 04 0001 Piediction and pievention ot
sudden caidiac death Piognoslic signilicance ol
piemature ventricular contractions (human)
•* ROIHL 18808 04 0003 Prediction and prevention of
sudden cardiac death Technical support (computei)
POIHL 19717 02 0046 Response ol the lung to injury
Bioengineeiing section
ROIHL 20374 03 Myocaidial function Risk factois and
future CHD (human)
ROIHL 20632 02 An optimal fetal heart monitor (human)
ROIHL 20674 02 Evaluation of caidiac function with
ladioactive liaceis
ROIHL 20835 02 Signal analysis of tuibulence study in
blood
ROIHL 2089503 0001 Cineangiogiaphic studies of
caidiovasculai system Videodensitometiy and valvular
leguigitation (human, dogs)
ROIHL 20895 03 0003 Cineangiogiaphic studies of
caidiovasculai system Densitometry in coionaiy stenosis
(human)
ROlHL-2089503 0005 Cineangiogiaphic studies of
caidiovasculai system Computeiized axial tomogiaphy-
Caidiac wall motion and infaiction (dogs)
R23HL21253-01 Anatomical models in computei aided
image analysis
ROIHL 2127801 Abnoimal caidiac wall motion viewed
ultrasonically (human, dogs, phantoms)
ROlHL-21654-01 Autonomic deteiminants of airhythmia
due to ischemia (cats)
ROlHL-21684-02 0004 Radionuclide infarct sizing and
therapy evaluation Image analysis -Kinetics of infarction,
ventricular function (human, animal)
ROlHL-21684-02 0005 Radionuclide infarct sizing and
therapy evaluation - Clinical evaluation of radioisotope
imaging methods for quantifying infarct size
ROlHL-21690-02 Sequential multinuclide study of acute
infarction (human, dogs)
ROlHL-21707-01 Quantification of infarct size by emission
tomography (human, dogs)
ROlHL-21710-01 Electrocardiographic methods of
quantifying infarct size (human, dogs)
ROlHL-2175102 0003 Thallium and antimyosin in
ischemia and infarction - Human studies-Ischemia and
infarction
** ROlHL-21785-01 Left ventricular wall motion analysis
ROlHL-21796-01 Applied pulsatile hemodynamics in
vascular surgery (dogs)
** ROlHL-21846-01 Cardiac failure detection by radiography
and optics (monkeys)
R23HL-22004-01 Imaging and EGG studies in acute and
chronic IHO (human)
ROlHL-22321-01 Cardiac output from the
pneumocardiogram (dogs)
ROlHL-22326-01 Noninvasive measurement of caidiac
output (dogs)
R23HL-22787-01 Caidiac volume by biplane
echocaidiography (human)
R01HL-23983-01 Quantitative ladiocaidiogiaphy (human,
dogs)
NOlHV-72924-04 Non-invasive detection of atheioscleiotic
lesions (human, animals)
NOlHV-72927-00 Systems foi non-invasive detection of
atheioscleiotic lesions (human)
NOlHV-72928-04 Develop high resolution ultiasonic
imaging techniques
BIOMEDICAL SYSTEMS AUTOMATED, COMPUTER
ASSISTED MEDICAL DECISION MAKING
SEE ALSO BIOMEDICAL SYSTEMS AUTOMATED, COMPUTER
ASSISTED DIAGNOSIS
M POlHL-04664-18 Caidiovasculai and lung dynamics
** POlHL-04664-18 0010 Caidiovasculai and lung dynamics
- Left ventiiculai dynamics (human)
POlHL-04664-18 0012 Caidiovascular and lung dynamics
- Quantitative single plane left ventiiculai angiogiaphy
(human)
** POlHL-04664-18 0015 Caidiovasculai and lung dynamics
- Computei system for the caidiovasculai laboratoiy
POlHL-06350-17 0015 Hemostasis reseaich piogram
project - Genetics (human)
ROlHL-07575-15 Analysis of time-coherent cardiovascular
data
R01HL-12085-10 Lipoprotein-carbohydrate metabolism
(human, rats)
P50HL-14138-05 0014 Center for leseaich on
atheioscleiosis - Core biostatistics laboratoiy
P50HL14214-07 0033 Newborn lung center for hyaline
membiane disease - Statistical modeling, predictive
classification in clinical management of HMD
(contd)
•Excludes routine methodology OR coveis only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Gram has subprojects descnbing specific reseaich aspects,
See Appendix foi investigators name and giant number.
Computer-
Regional
BIO
" P60HL17292-04 0029 Vermont Lung Center
assisted pre-operative evaluation (human)
** P60HL-1 7292-04 0031 Vermont Lung Center
respiratory computer network
P50HL-1 7667-04 0029 Study ot ischemic heart disease ■
Computer diagnosis of cardiac arrhythmias after open
heart surgery (human)
•* P50HL-17670-04 0001 Study of ischemic heart disease -
Data management
ROlHL-22963-01 Symbolic logic analysis of congenital
heart disease (human)
BIOMEDICAl SYSTEMS AUTOMATED, COMPUTER
ASSISTED PATIENT CARE
SEE ALSO BIOMEDICAL SYSTEMS AUTOMATED. PATIENT
MONITORING (MONITORING DEVICES)
SEE ALSO HOSPITALS, INTENSIVE CARE UNITS
P01HL-06308-18 0044 Mechanisms and therapy of
circulatory disease - Echocardiography to determine site of
ectopic impulse formation (human, dogs)
" POlHL-11310-12 0065 Mechanisms of cardiovascular
disease ■ Algorithms for arterial pressure by automatic
vasoactive agents control (human)
P01HL-12738-I0 0092 Physiologic pharmacology and its
clinical applications - Subendocardial ischemia following
open heart surgery (human)
M POIHL 13737-07 Assisted circulation
POlHl-13737-07 0013 Assisted circulation - Incorporation
of sensors (human, dogs)
** POlHL-13737-07 0025 Assisted circulation - Driving
system based on quantitative criteria (human dogs)
*• POlHL-13737-07 0039 Assisted circulation ■ Computer
controlled intraortic balloon pumping
** POlHL-16851-04 0012 Human red cell membrane m
health and disease - Computer unit -Core facility
P60HL-17269-04 0030 National heart and blood vessel
research and demonstration center • Cardiovascular
engineering laboratories (human)
** P60HL1 7269-04 0031 National heart and blood vessel
research and demonstration center - Computer-assisted
data acquisition and clinical data processing
P60HL17292-04 0029 Vermont Lung Center - Computer-
assisted pre-operative evaluation (human)
P50HL-17651-04 0034 Ischemic heart disease specialized
center of research ■ Core facilities -Data management
P50HL-1 7667-04 0029 Study of ischemic heart disease ■
Computer diagnosis of cardiac arrhythmias after open
heart surgery (human)
P50HL-18323-04 0034 SCOR hypertension center - Core-
Data management
ROlHL-22517-01 Engineering development of an ultrasonic
ventilometer (human)
BIOMEDICAL SYSTEMS AUTOMATED, COMPUTER
PROCESSING OF CLINICAL DATA
SEE ALSO BIOMEDICAL SYSTEMS AUTOMATED, COMPUTER
ASSISTED DIAGNOSIS
SEE ALSO BIOMEDICAL SYSTEMS AUTOMATED. COMPUTER
ASSISTED MEDICAL DECISION MAKING
NOlHB-72982-03 Statistical coordinating center for sickle
cell disease
R01HL02254-23 Blood coagulation and hemorrhagic
disease (human, animals)
ROlHL-02799-22 Abnormal hemoglobins (human)
ROlHL-03429-18 Central nervous system and coronary
heart disease (human)
POlHL-04664-18 0001 Cardiovascular and lung dynamics
- X-ray projection image videodensitometry (dogs)
P01HL0466418 0003 Cardiovascular and lung dynamics
- X-ray projection image videometry (human, dogs)
POlHL-04664-18 0005 Cardiovascular and lung dynamics
- Applications of current research, equipment and
techniques
P01HL04664-18 0010 Cardiovascular and lung dynamics
■ Left ventricular dynamics (human)
POlHL-04664-18 0011 Cardiovascular and lung dynamics
• Detection of abnormal segments of the human ventricle
by measure of asynergy
POlHL-04664-18 0013 Cardiovascular and lung dynamics
- Ventricular function in coronary disease using NTG and
ventriculograms (human)
P01HL0466418 0014 Cardiovascular and lung dynamics
• Clinical application of computer analysis of ventricular
wall motion
POlHL-04664-18 0015 Cardiovascular and lung dynamics
- Computer system for the cardiovascular laboratory
ROlHL-04666-19 Artificially paced hearts-Technology,
physiology (human, dogs)
POlHL-0628518 0146 Cardiovascular-respiratory
physiology and biochemistry - Pathogenesis and detection
of hypoxic pulmonary edema (human, animals)
POlHL-06296-18 0003 Cardiovascular and pulmonary
adaptation to stress - Human exercise studies (human.
dogs)
P01HL-06308I8 0010 Mechanisms and therapy of
circulatory disease - Ventricular arrhythmias during exercise
to CHD and myocardial ischemia (human)
P01HL06308-18 0011 Mechanisms and therapy of
circulatory disease • Blood flow and electrical dysfunction
in ventricular arrhythmia (human)
POlHL-06314-17 0065 Immunologic mechanisms in
cardiovascular disease - Transplantation biology and
clinical transplantation
40
ROlHL-07139-17 Cardiodynamics and metabolism of
congestive failure (human, dogs)
ROlHL-07575-15 Analysis of time-coherent cardiovascular
data
ROlHL-0947411 Natural history-congenital heart defects-
Joint study (human)
ROlHL-1041712 Multiple systems in electrocardiography
(human)
ROlHL-107 18-10 Natural history of congenital heart
defects-Joint study (human)
POIHLI 1307-12 0002 Biophysical studies in pediatric
cardiology Cardiac extracellular electrophysiology (human.
dog, chimpanzee)
** POlHL-l 1307-12 9001 Biophysical studies in pediatric
cardiology ■ Core support -computer science
POlHL-1131012 0071 Mechanisms of cardiovascular
disease - Electrophysiological studies of atrial flutter
(human)
POIHLI 13 10-12 0072 Mechanisms of cardiovascular
disease - Electrophysiological studies of atrial tachycardia
with block (human)
POlHL-1131012 0081 Mechanisms of cardiovascular
disease ■ Analysis of regional left ventricular function
(human)
POlHL-l 13 10-12 0083 Mechanisms of cardiovascular
disease - Ventricular volume and hemodynamics in adult
congenital heart disease
POlHL-11310-12 0084 Mechanisms of cardiovascular
disease - Evaluation of cardiac function in chronic renal
failure (human)
POIHL 11310-12 0092 Mechanisms of cardiovascular
disease - Exercise electrophysiology (human)
POIHLI 13 10-12 0093 Mechanisms of cardiovascular
disease ■ Multiple dipole electrocardiogram project (human,
dogs)
POlHL-1131012 9002 Mechanisms of cardiovascular
disease • Core support-centralized electronic laboratory
ROlHL-1 1907-08 Mechanisms of physiological responses
to exercise (human, dogs)
POlHL-1237310 0014 Cardiopulmonary physiology and
pathophysiology ■ Analog digital computation and
simulation facility
R01HL1254207 Natural history, congenital heart defects-
Joint study (human)
P01HL12738-10 0117 Physiologic pharmacology and its
clinical applications • Ventricular arrhythmias in ischemic
heart disease (human)
P01HL13330-08 0062 Mechanical circulatory support -
CORE facilities
POlHL-13737-07 0013 Assisted circulation - Incorporation
of sensors (human, dogs)
P01HL1373707 0025 Assisted circulation ■ Driving
system based on quantitative criteria (human, dogs)
* R01HL13885-08 9002 Cystic fibrosis and pulmonary
disease ■ Computer core facility (human)
ROlHL-1397407 Ventricular premature beats and sudden
coronary death (human)
P50HL-1413607 0005 Pulmonary SCOR-Airways
obstructive diseases - Radiographic studies of airways
obstructive disease (human)
* P50HL-141 36-07 9001 Pulmonary SCOR-Airways
obstructive diseases - Biometrics core
P50HL-14138-05 0014 Center for research on
atherosclerosis - Core biostatistics laboratory
P50HL-1413805 0016 Center for research on
atherosclerosis - Computer analysis of angiograms
* P50HL-141 59-08 0023 Specialized center of research In
hypertension - Core computation
P50HL-14164-07 0039 A/S SCOR-Comparative and
experimental atherosclerosis - Statistical resource and
research management unit
P50HL-141 92-08 0008 Specialized center of research in
hypertension • New radiographic methods-Recognition of
renovascular hypertension (human, dog)
P50HL-142 12-07 0017 Correlated studies of pulmonary
fibrosis - Biometry core
P50HL-142 14-07 0033 Newborn lung center for hyaline
membrane disease - Statistical modeling, predictive
classification in clinical management of HMD
P50HL-14214.07 0036 Newborn lung center for hyaline
membrane disease • Core-Biomedical engineering
P50HL-142 18-07 0011 Pulmonary SCOR-Newborn lung
center - Administrative and computer core
P50HL-142 18-07 0012 Pulmonary SCOR-Newborn lung
center - Longitudinal study of RDS-On-line fetal and
neonatal monitoring (human)
ROlHL-143 78-07 Lipemias and reconstructive cardiac
surgery (human)
POlHL-14388-07 0183 Regulation of the circulation in
pathological states - Vasopressin in cardiovascular
regulation (dogs, rats)
P01HL144 14-07 0007 Environmental influences on
cardiorespiratory and cellular functions - Neural control of
respiration (human, cats)
R01HL14688-05 Myocardial assessment by inverse
electrocardiography (monkey)
R01HL1504706 Digital computer analysis of the
electrocardiogram (human)
P60HL151 57-07 0002 Comprehensive center for sickle
cell disease - Central data bank and research file
P60HL15160-07 0009 Center for sickle cell disease -
Natural history of sickle cell disease (human)
Computer controlled two dimensional
Mathematical models for studying sickle-
Structure and function of blood proteins
Innervation of coronary arteries and heart
Ultrasonic measurement of cardiac
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level
Oriented significantly to above subject.
M Grant has subproiects describing specific research aspects.
See Appendix for investigator's name and grant number.
BIO
ROlHL-15190-07 Physiological basis of arrhythmias and
their therapy (human)
P01HL1526505 0011 Program on surgical control of the
hyperlipidemias - Central electrocardiography laboratory
(human)
■* P50HL- 15389-0 7 0020 Pulmonary SCOR-Hypersensitivity
pneumonitis - Computer applications and data analysis
core
ROlHL-15390-12 Regulation of blood flow in the
microcirculation
ROlHL-15676-06 The role of occult myocardial failure in
human shock (human, dogs)
P60HL-16005-05 0018 Comprehensive sickle cell center -
Comprehensive study-Natural history of sickle cell disease
in adults (human)
P60HL-16008-06 0012 Wayne State University
comprehensive sickle cell center - Central data
management -Computer system
ROlHL-16403-05 Prognostication by computer-Analyzed
vectorcardiogram (human)
R01HL1646105 Late results of valve replacement-
Computer analysis (human)
R01HL1648404 Radiographic vcntriculometry for coronary
heart disease (human)
ROlHL-1648705
echocardiography
R01HL1658004
cell disease
ROlHL-16601-05
(human, cattle)
R01HL1665706
(rats)
R01HL16759-05
geometry and flow
ROlHL-16791-03 Computer linkage for a dual camera
system
R01HL16901-05 Multipolar linkage between heart
geometry and surface (human, dogs)
POlHL-16910-05 0007 Regulation of the peripheral
circulation - CNS -Behavioral influences on circulation
(baboons)
' P60HL-1 7269-04 0031 National heart and blood vessel
research and demonstration center - Computer-assisted
data acquisition and clinical data processing
P60HL- 17292-04 0031 Vermont Lung Center - Regional
respiratory computer network
ROlHL-17358-04 Ventilatory adjustments for optimal
oxygenation (dogs, rats)
R01HL1757804 Exercise performance in children with
heart disease
R01HL-17604-03 Wearable blood pressure and ECG
recording system
P50HL-17646-04 0002 Study of ischemic heart disease -
Core data management
P50HL-17646-04 0010 Study of ischemic heart disease ■
Compliance in ischemic myocardium-Altered cardiac
performance (human, dogs)
P50HL-17648-04 0032 Study of ischemic heart disease -
Data management-Statistics and data files
P50HL-17648-04 0033 Study of ischemic heart disease ■
Data management-Electrocardiographic analysis system
P50HL-1 7648-04 0034 Study of ischemic heart disease •
Data management-Hemodynamic data
P50HL-17651-04 0033 Ischemic heart disease specialized
center of research - Core facilities -Computer sciences
P50HL-1765104 0034 Ischemic heart disease specialized
center of research - Core facilities -Data management
P50HL-17655-04 0012 Study of ischemic heart disease -
DATA management
P50HL-17665-04 0018 Study of ischemic heart disease -
Computer correlation of data-Patients with ischemic heart
disease
P50HL-1766504 0027 Study of ischemic heart disease -
Positron imaging of regional myocardial perfusion (human,
dog)
P50HL-1 7665-04 0030 Study of ischemic heart disease -
Data management
P50HL-17667-04 0001 Study of ischemic heart disease -
Natural history of ischemic heart disease (human)
P50HL- 17667-04 0030 Study of ischemic heart disease -
Computerized clinical data acquisition and processing
P50HL-17667-04 0039 Study of ischemic heart disease -
Core human investigative laboratories
P50HL-1 7667-04 0041 Study of ischemic heart disease -
Biophysical sciences core-Data collection and retrieval
P50HL17667-04 0042 Study of ischemic heart disease ■
Core-Central instrumentation and software
P50HL-1 7667-04 0044 Study of ischemic heart disease ■
Core-Data management and analysis
P50HL-17670-04 0001 Study of ischemic heart disease ■
Data management
P50HL-1 7670-04 0008 Study of ischemic heart disease -
Surgical treatment of cardiac rhythm disorders (human,
dogs)
P50HL17670-04 0014 Study of ischemic heart disease ■
Real time ultrasound imaging in ischemic heart disease
(human, dog)
P50HL-17670-04 0018 Study of ischemic heart disease -
Core electrocardiogram laboratory (human)
P50HL-17682-04 0009 Study of ischemic heart disease -
Computer core unit
(contd)
BIO
POIHI 1/'3I 04 0006 Physiological b»Ms ol pulmoniiY
dliHse Vantiltlion ptilusion latios (human, dots)
POIHI \Ui\ 04 OOU Physiological biiMS ol pulmomiy
diseasa SlalistitJ and computing Coi«
ROIMI 17993 04 000.' Vonliiculai dynamics lioiii
surgically inserted maikeis Ult venliicio (unction in
human caidiac allotiatt
ROIHI 18144 03 Piepiocessoi sys(«im loi caidiogums
(human)
PSOHl 18318 03 0001 Pathogenesis and complications ol
hypertension Coie clinical piogiam
PbOHl 18323 04 0033 SCOR hypertension center Cote
lalwratory Renin, aldosterone and bradykinin methodology
• PMHl 183?3 04 0034 SCOR hypertension center Core
Data management
ROIHI 18672 03 Dynamic studies ol clot structure
formation (human)
ROIHI 1877604 Prevention ot acute and (atal
cardiovascular disease (human)
ROIHI 1880804 0001 Prediction and prevention of
sudden cardiac death Prognostic signilicance ol
premature ventricular contractions (human)
ROIHL 1880804 0003 Prediction and prevention of
sudden cardiac death Technical support (computer)
ROIHI 1896803 Computer technology lor transaxial
tomography
ROIHL 19053 03 Vascular anatomy of the telencephalon
(human)
P50H1. 19153 02 0008 SCOR Pulmonary edemas Eitology,
pathogenesis Core Biomedical engineering
*• P50HL 1917002 0010 Harvard pulmonary SCOR Chronic
diseases of the airways Computer Core
P50HL 19362 02 0017 A/S SCOR Atherosclerosis in
nonhuman primates Core laboratory- Data management,
statistical analysis
ROIHL 1940603 Grading of atherosclerosis by CW dopplei
ultrasound (human, dogs)
ROIHL 19451 03 0001 Functional characteristics of the
left heart Ventricular performance using epicardial
radiopaque markers (human)
R01HL19451-03 0003 functional characteristics of the
left heart ■ Left ventricular segmental contraction (human,
dogs)
R01HL19451-03 0004 Functional characteristics of the
left heart - Quantitative coronary arteriography (human)
P01HL1971702 0044 Response of the lung to injury •
Lung sound analysis (human)
R01HL1979102 Ultrasonic monitoring visceral blood
vessels
R01HL1986403 0002 Blood pressure of children and
young adults ■ Data epidemiology center
ROlHL-2027402 Gated imaging with the MGH x-ray
camera
ROlHL-2035602 Development and evaluation of an
artificial heart (calves)
ROlHL-20597-02 Electrophysiologic correlates of
myocardial ischemia (human, dogs, rabbits)
ROlHL-20677-02 Radionuclide studies in congenital heart
disease
ROlHL-20724-01 Behavioral consequences of hypertension
(human)
ROlHL-20751-01 High speed liquid chromatography of
hemoglobins (human)
ROlHL-21052-01 Evaluation of a digitalis therapy advisor
R01HL-21088-02 Genetic patterns in deaths from Ml and
stroke in Utah
ROlHL-21221-02 Clinical antiarrhythmic and
pharmacodynamic studies
R23HL-2125301 Anatomical models in computer-aided
image analysis
POlHL-21584-02 0006 Respiratory mechanics in normal
and abnormal states - Respiratory mechanics in health and
disease (human, pigs)
*• P01HL-2158402 9002 Respiratory mechanics in normal
and abnormal states - Computational and statistical core
facility
ROlHL-22636-01 Newborn lung function during
mechanical ventilation (human)
NOlHR-62901-04 Measure pulmonary function in infants
and children (also dogs, rabbits)
NOlHV-12156-10 Lipid research clinic
NOIHV-12158-10 Establishment of a lipid research clinic
NOlHV-12159-09 Lipid research clinic
NOlHV-12160-15 Establishment of a lipid research clinic
N01HV-22914-08 Establishment of a lipid research clinic
NOlHV-32931-09 Establishment of a lipid research clinic
center
NOlHV-53015-09 Establishment of a lipid research clinic
(human)
NOlHV-72927-00 Systems for non-invasive detection of
atherosclerotic lesions (human)
N01HV-72928-04 Develop high resolution ultrasonic
imaging techniques
BIOMEDICAL SYSTEMS AUTOMATED, COMPUTER
PROCESSING OF LABORATORY DATA
(GENERAL)
ROlHL-01015-27 Hypertension and left ventricular
hypertrophy (dogs)
R01HL-02363-20 Kinetics of water and electrolytes in
shock (dogs, rats)
41
POIHI 04664 IB 0001 Cardiovascular and lung dynamics
X ray pro|mlion image vldeodensilumetry (dog%)
POIHI 0(i?8;i 18 0173 Ciidioviscular respiratory
physiology and biochemistry Skeletal and cardiac muscle
lunction
POIHI 06296 18 0007 Cardiovascular and pulmonaiy
adaptation to stress Cardiovascular control during
isometric exercise (cats)
ROIHt u;;23 I'j Retlex control of vascular capacitance in
shock
ROIHI 0/8/8 16 Metabolism of neutral sterols (rats.
rabbits)
POIHI 08214 15 0006 Chemical and biological properties
ol lipids Analysis and properties of lipids
' POIHI 08805 15 0043 Regulation of ventilation and
pulmonary circulation Computer core lacility
POIHL 08899 14 0028 Tolerance to respiratory gases in
health and disease Inert gas exchange, oxygen influences
organs and tissues (human, rabbits, dogs)
ROIHI 09921 13 Mechanisms related to congestive heart
failure (dogs, human, rat)
ROIHL 10330 11 Physiological mechanics of the heart and
arteries (dogs, rabbits, horses)
ROIHL 10881 13 Structure and function of
microcirculation (hamsters, rats, cats, dogs)
• POIHL 11307 12 9001 Biophysical studies in pediatric
cardiology Core support computer science
POIHL 11307-12 9002 Biophysical studies in pediatric
cardiology Biomedical engineering
POIHL 11310 12 0093 Mechanisms of cardiovascular
disease Multiple dipole electrocardiogram proiect (human,
dogs)
POIHL 12373 10 0014 Cardiopulmonary physiology and
pathophysiology Analog digital computation and
simulation facility
ROlHL-12711 09 Mathematical approach to cardiovascular
mechanics (human, animals)
POIHL 12738 10 0044 Physiologic pharmacology and its
clinical applications Cardioactive drugs and
electrophysiological properties of cardiac cells (sheep)
ROIHL 12879-09 0010 Pulmonary transport and
metabolism in vivo - Lung morphometry in control and
edematous lungs (dogs)
ROIHL 13036-08 Coronary thrombosis-Effects on
myocardium and in vivo detection (dogs, monkeys)
ROlHL-13187-09 Central neural control of cardiovascular
function (cats)
POlHL-13480-09 0017 Cardiac electrophysiology - Body
surface potential mapping (human, dogs)
** POlHL-1348009 0032 Cardiac electrophysiology Cardiac
activation sequence (dogs)
POlHL-13737-07 0007 Assisted circulation -
Determination of cardiac status by use of balloon pump
(dogs)
POlHL-1373707 0034 Assisted circulation - Phasic aortic
flow and cardiac output from phasic pressures (dogs)
POlHL-13737-07 0035 Assisted circulation ■ Mapping the
geometry and elasticity of the aorta
POlHL-1373808 0005 Cardiac assist devices and
artificial hearts - Development of new materials for
artificial heart and assist devices (sheep, dog)
ROlHL-13917-20 Secretion and effects of adrenal
hormones (human, rabbits, sheep)
P50HL-141 59-08 0023 Specialized center of research in
hypertension - Core computation
POlHL-14388-07 0214 Regulation of the circulation in
pathological states - Deformation pattern and stress
analysis of the left ventricle
POlHL-14388-07 0215 Regulation of the circulation in
pathological states - Left ventricle model in
pathophysiologic states
POlHL-14388-07 0217 Regulation of the circulation in
pathological states ■ Fluid mechanics of aortic flow (dogs,
human)
** POlHL-1441407 9001 Environmental influences on
cardiorespiratory and cellular functions ■ Laboratory core
facility
** P01HL-U4 14-07 9002 Environmental influences on
cardiorespiratory and cellular functions - Core-Computer
facility
R01HL1464507 Blood flow measurement by ultrasonic
catheter tip methods (human, dogs)
P50HL-15092-07 0001 Immune and fibrotic response to
occupational environments • X-ray diffraction study-Dust
exposure in asbestos cement products manufacturing
** P01HL151 9407 9002 Pathophysiology of
cardiopulmonary dysfunction - Data processing laboratory
core
ROlHL-15622-05 Computer simulation in cardiology (rats,
dogs)
ROlHL-15698-12 Factors affecting the action of
anticoagulants (rats, human)
ROlHL-15799-04 Effect of anesthetics on myocardial
function (cats)
P60HL-16005-05 0015 Comprehensive sickle cell center -
Molecular basis for the sickling phenomenon
ROlHL-16076-06 Electrophysiology of fibrillation and
defibrillation (human)
ROlHL-16093-05 Functional properties of hemoglobin and
erythrocytes
HIO
POIHI 16178 05 0004 Control of ventilation in htallh
and diwise l»«urotnn»mille(» in the iiipiralory %r»l«<"
(cats)
POIHI 168/8 05 000') Control ot venlllalion in hiillh
and disease Program core
ROIHI 16901 O'l Multipolar linkage ImIwmii hml
geometry and surlato (human, dogs)
POIHI 16910 05 0008 Regulation of the ptriphtril
circulation Circulation to bone (dogs, baboons)
P60Ht 1/269 04 0016 National heart and blood vejtti
research and demonstration center New analytical
methodology lor atherosclerosis studies
ROIHL 1/452 04 Depolarization inductd cirdiac
automaticity (human, animals)
ROIHI 1/532 04 Infarct si« ECG. angio, path, orrelalion
in dogs
ROIHL 17592 03 Activation and contraction heal in
enlarged hearts (rabbits)
ROIHL 17702 04 Electro optical dyes as probes c( heart
excitability
POIHL 1//3I 04 0002 Physiological basis of pulmonary
disease Biomechanics of the lung (frogs, cats)
POIHL 17731 04 0012 Physiological basis ol p'llmonary
disease Statistics and computing Core
ROIHL 17859 04 Computational methods in cardiac fluid
dynamics
ROIHL 1799804 Regulatory mechanisms in blood
circulation (dogs)
ROIHL 18156 02 Hemodynamics in curved arteries
POIHL 18208 04 0002 Center for the study of blood cell
rheology Holography of RBC shape (human)
POIHL 18208 04 0005 Center for the study of hlood cell
rheology RBC deformability and capillary flow
interrelations (human, mice)
* POIHL 18575 03 0013 Mechanisms of vascular changes
in hypertension Biostatistical core
ROIHL 18794 04 Prospective studies of conduction disease
(human)
ROlHL-1886803 Development of vertebrate vascular
control systems (reptiles, amphibians)
ROIHL 18969 02 Arterial wall oxygenation (rabbits.' dogs)
POIHL 18974 03 0017 Experimental neurogenic
hypertension program Computer physiology core
ROlHL-19045-03 Electrophysiology of cardiac automaticity
(human, dogs)
R01HL19076-03 Vagal control of heart rate- A biophysical
model (rabbits)
P50HL-19153-02 0008 SCOR Pulmonary edemas Eitology.
pathogenesis Core- Biomedical engineering
ROlHL-19460-03 Mechanics of the papillary muscle and
the left ventricle (cats, rabbits)
POlHL-197 17-02 0046 Response of the lung tj injury •
Bioengineering section
ROIHL 19824-02 Mass transfer in the mictocir-ulation
ROIHL 1983002 Shear to aortic histamine synihcsis and
permeability (dogs)
** ROlHL-20678-02 Cardiovascular adaptation to stress in
disease states (dogs)
R01HL-20800-17 Neural basis of respiratory and
vasomotor activity (cats)
** POlHL-21584-02 9002 Respiratory mechanics in normal
and abnormal states - Computational and statistic-l core
facility
ROlHL-21672-01 Antiarrhythmic drug action on VIVIAZ of
cardiac cells
ROlHL-21764-01 Ultramicroanalysis of prostaglandins and
related compounds (rats)
ROlHL-22136-02 Histamine and cardiac adenyl cyclase
ROlHL-22223-01 The cardiopulmonary junction (dogs.
models)
ROlHL-22329-01 Active prosthetic myocardium-Effects on
LV function (dogs)
ROlHL-22562-02 Mechanism of cardiac action potential
propagation (tunicates)
NOlHV-32933-07 Hypertension detection and follow-up
program central laboratory (human)
BIOMEDICAL SYSTEMS AUTOMATED,
ELECTRONIC RECORDING SYSTEMS
POlHL-12373-10 0015 Cardiopulmonary physiology and
pathophysiology - Cine angiographic-hemodynamic facility
ROlHL-16759-05 Ultrasonic measurement of cardiac
geometry and flow
ROlHL-18040-04 Waveform dependency in defibrillation
(calves)
BIOMEDICAL SYSTEMS AUTOMATED, HEALTH
CARE FACILITIES (SYSTEMS) AUTOMATED
SEE ALSO BIOMEDICAL SYSTEMS AUTOMATED, COMPUTER
ASSISTED DIAGNOSIS
SEE ALSO BIOMEDICAL SYSTEMS AUTOMATED, COMPUTER
ASSISTED MEDICAL DECISION MAKING
SEE ALSO BIOMEDICAL SYSTEMS AUTOMATED, COMPUTER
ASSISTED PATIENT CARE
SEE ALSO BIOMEDICAL SYSTEMS AUTOMATED. COMPUTER
PROCESSING OF CLINICAL DATA
SEE ALSO BIOMEDICAL SYSTEMS AUTOMATED, PATIENT
MONITORING (MONITORING DEVICES)
R01HL16791-03 Computer linkage for a dual camera
system
:fntd)
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
**Oriented signitlcantty to above subject.
M Grant has subproiects describing specific research aspects.
See Appendix for Investigator's name and grant number.
Vermont Lung Center - Health
Study of ischemic heart disease
BIO
BIOMEDICAL SYSTEMS AUTOMATED, HEALTH
CARE FACILITIES (SYSTEMS) INFORMATION
SYSTEMS
SEE ALSO HEALTH RECORDS (SYSTEMS) AUTOMATED
P01HL0901M5 0017 A research and resource program
in blood - Operations research laboratory
** P01HL10436-13 0009 A multidisciplinary study of
congenital heart disease • Pathophysiology and
morphogenesis of congenital heart disease (human)
R01HL-1388108 The American Red Cross National
Fractionation Center
" P50HL-1423605 0010 Prevention of premature
arteriosclerosis ■ Computer programs
** P60HL-1515707 0002 Comprehensive center for sickle
cell disease ■ Central data bank and research file
P60HL-15168-D7 0002 Comprehensive sickle cell disease
center ■ Patient care
** P01HL15265-05 0004 Program on surgical control of the
hyperhpidemlas - Coordinating center and central data
processing facility
** P60HL- 16008-06 0012 Wayne State University
comprehensive sickle cell center • Central data
management-Computer system
R01HL1679103 Computer linkage for a dual camera
system
P60HL17265-04 0001 Community blood resource center
support - Demonstration and evaluation
** P60HL- 17269-04 0031 National heart and blood vessel
research and demonstration center - Computer-assisted
data acquisition and clinical data processing
" P60HL- 17292-04 0023
information resources
** P50HL-17646-04 0002
Core data management
" P50HL- 1765 1-04 0034 Ischemic heart disease specialized
center of research ■ Core facilities -Data management
** P50HL1765504 0012 Study of ischemic heart disease ■
DATA management
" P50HL-17665-04 0018 Study of ischemic heart disease -
Computer correlation of data-Patients with Ischemic heart
disease
** P50HL1766504 0030 Study of ischemic heart disease ■
Data management
** P50HL-1 7667-04 0001 Study of ischemic heart disease -
Natural history of Ischemic heart disease (human)
** P50HL1 7667-04 0030 Study of Ischemic heart disease -
Computerized clinical data acquisition and processing
P50HL-1 7667-04 0038 Study of ischemic heart disease -
Clinical core unit
" P50HL-17667-04 0041 Study of Ischemic heart disease -
Biophysical sciences core-Data collection and retrieval
** P50HL1766704 0042 Study of ischemic heart disease -
Core -Central instrumentation and software
** P50HL-17667 04 0044 Study of ischemic heart disease ■
Core -Data management and analysis
" P50HL-1 7670-04 0001
Data management
** P50HL17682-04 0009
Computer core unit
" P50HL-18323-04 0034
Data management
NOlHV-22914-08 Establishment of a lipid research clinic
NOIHV 32973-12 Coordinating center for collaborative
studies on coronary artery surgery
BIOMEDICAL SYSTEMS AUTOMATED, MAGNETIC
RECORDING SYSTEMS
" POIHL 12738-10 0128 Physiologic pharmacology and Its
clinical applications - Recording electrograms from
specialized cardiac tissues (human, dogs)
R01HL16791-03 Computer linkage for a dual camera
system
BIOMEDICAL SYSTEMS AUTOMATED,
MONITORING DEVICES
SEE ALSO AIR SAMPLING-MONITORING
SEE ALSO BIOMEDICAL SYSTEMS AUTOMATED PATIENT
MONITORING (MONITORING DEVICES)
SEE ALSO HEART DISORDERS DIAGNOSIS
ELECTROCARDIOGRAPHY MONITOR*
ROlHL-01015-27 Hypertension and left ventricular
hypertrophy (dogs)
R01HL-n945-10 Synthesis of artificial lung and kidney
systems (sheep, mice, swine)
POlHL-13330-08 0034 Mechanical circulatory support ■ In
vivo test and evaluation of left ventricular bypass pumps
(human, cattle)
P01HL13330-08 0062 Mechanical circulatory support -
CORE facilities
ROlHL-13426-09 Left ventricular bypass for myocardial
infarction (cattle, human)
ROIHL-13988-07 Elimination of reoperative cardiac
pacemaker surgery (dogs)
** ROlHL-16292-05 0020 Surgery and non-obstructive
coronary insufficiency ■ Limitation of transthoracic ECG In
detecting subendocardial ischemia (dogs)
** ROIHL-16292-05 0021 Surgery and non-obstructive
coronary insufficiency ■ Pulsatile assistance on
subendocardial perfusion during bypass (dogs)
ROIHL 1648705 Computer controlled two dimensional
echocardiography
Study of ischemic heart disease ■
Study of Ischemic heart disease -
SCOR hypertension center - Core-
42
** P60HL- 17269-04 0030 National heart and blood vessel
research and demonstration center ■ Cardiovascular
engineering laboratories (human)
P50HL-17682-04 0014 Study of Ischemic heart disease ■
Myocardial Ischemia -Instrumentation and technique (dogs.
baboons)
P50HL- 17682-04 0015 Study of ischemic heart disease -
Acute myocardial ischemia and Infarction and their
reversibility (dogs, baboons)
ROIHL- 18084-03 Artificial heart and related problems
(calves)
ROlHL-18947-02 Indirect mean arterial pressure
(mammals)
P50HL-19187-02 0009 Pediatric pulmonary SCOR -Hyaline
membrane disease - Noninvasive measurement and
monitoring of arterial oxygen tension (dogs, sheep)
ROlHL-19678-01 Quantification of intrathoracic fluid by
Impedance (human, dogs)
ROlHL-20354-02 Direct determination of oxygen tension in
the clinical environment (human, dogs)
ROlHL-20356-02 Development and evaluation of an
artificial heart (calves)
ROlHL-20632-02 An optimal fetal heart monitor (human)
ROlHL-22274-01 Quantltating In series effects In cardiac
arrhythmias (dogs)
ROlHL-22604-01 Non-invasive system for arteriosclerosis
studies (human)
** ROlHL-22854-01 Non-Invasive blood pressure
measurement (rats)
N01HR-62920-02 Noninvasive diagnosis of pulmonary
hypertension (dog, human)
BIOMEDICAL SYSTEMS AUTOMATED, PATIENT
MONITORING (MONITORING DEVICES)
SEE ALSO HEART DISORDERS DIAGNOSIS,
ELECTROCARDIOGRAPHY MONITOR*
SEE ALSO HOSPITALS, INTENSIVE CARE UNITS
ROlHL-09609-11 Lung volume and breathing mechanics
during anesthesia (human)
POlHL-1 1310-12 0058 Mechanisms of cardiovascular
disease Dynamic response to vasodilating agents
postoperatively (human)
ROlHL-13341-06 Lymph -An Indication of splanchnic tissue
respiration (dogs, human, rats)
ROlHL-13974-07 Ventricular premature beats and sudden
coronary death (human)
P50HL-1421407 0036 Newborn lung center for hyaline
membrane disease Core-Blomedical engineering
** P50HL-14218-07 0012 Pulmonary SCOR -Newborn lung
center - Longitudinal study of RDS -On line fetal and
neonatal monitoring (human)
** P50HL-14218-07 0013 Pulmonary SCOR-Newborn lung
center - Longitudinal study of RDS -Monitoring fetal P02
and PC02 during labor (human)
** P50HL-14218-07 0014 Pulmonary SCOR-Newborn lung
center - Longitudinal study of RDS-MonitorIng fetal
breathing movements (human)
ROlHL-16487-05 Computer controlled two dimensional
echocardiography
ROlHL-16830-05 Noninvasive determination of aortic
blood velocities (human)
** R01HL-17604-03 Wearable blood pressure and ECG
recording system
P50HL-1 7646-04 0001 Study of Ischemic heart disease -
Core clinical Investigation unit
P50HL-1 7646-04 0002 Study of Ischemic heart disease -
Core data management
** P50HL- 17648-04 0033 Study of ischemic heart disease -
Data management -Electrocardiographic analysis system
P50HL-1 7651-04 0033 Ischemic heart disease specialized
center of research ■ Core facilities-Computer sciences
P50HL-1765104 0035 Ischemic heart disease specialized
center of research - Core facllitles-Biomedical engineering,
biophysics
♦* P50HL-17651-04 0047 Ischemic heart disease specialized
center of research - Clinical core -Automated arrtiythmia
monitoring system
P50HL1766504 0030 Study of Ischemic heart disease -
Data management
** P50HL 17667-04 0018 Study of Ischemic heart disease ■
Arrhythmias in ischemic heart disease (human)
P50HL1766704 0029 Study of ischemic heart disease -
Computer diagnosis of cardiac arrhythmias after open
heart surgery (human)
'* P50HL-17667-04 0030 Study of ischemic heart disease -
Computerized clinical data acquisition and processing
P50HL-17667-04 0039 Study of ischemic heart disease -
Core human Investigative laboratories
P50HL-17667-04 0042 Study of ischemic heart disease ■
Core -Central instrumentation and software
P50HL1 7682-04 0008 Study of ischemic heart disease -
Clinical core unit
P50HL-1 7682-04 0009 Study of ischemic heart disease -
Computer core unit
ROlHL-18710-02 Non-invasive reflection oximetry In
peripheral tissue (dogs)
P50HL-1919002 0001 Pulmonary SCOR -Pathophysiology,
management of IRDS - Core-Clinical research center
(infants)
* P50HL-19190-02 0009
management of IRDS
Pulmonary SCOR-Pathophysiology,
Developing non-invasive neonatal
pulmonary monitoring systems (rabbit, human)
•ExclucJes routine methodology OR covets only general projects wtiich preclude indexing
■•Oriented significantly to above subject
at the specific level.
M Grant lias subprojects describing specific researcli aspects.
See Appendix tor investigator's name and grant number.
BIO
R01HL-19414-D3 Protection of myocardium during cardiac
surgery (dogs, cats, human)
RO 1 HL-19844-02 Behavioral control of essential
hypertension (human)
ROIHL 19973-01 Non-invasive sickled cell monitor
development (human)
ROlHL-19993-02 Optical detection of platelet aggregates
(human, baboons)
R01HL-20024-03 Therapeutic aerosols-Characteristics and
retention (human, dogs)
ROlHL-20110-02 Microwave methods of lung water
measurement (dogs, phantom models)
** ROlHL-20351-02 A self-calibrating in vivo blood gas
monitor (dogs. Infants)
ROlHL-20364-01 Episodic hypertension associated with
human behavior (air traffic controllers)
ROlHL-22321-01 Cardiac output from the
pneumocardiogram (dogs)
** ROlHL-22417-01 Microprocessors In medical applications
(dogs)
** ROlHL-22517-01 Engineering development of an ultrasonic
ventllometer (human)
** ROlHL-22636-01 Newborn lung function during
mechanical ventilation (human)
** ROlHL-228 15-01 Regional myocardial function after
revascularization (dogs)
BIOMEDICAL SYSTEMS AUTOMATED,
TELEMEDICINE (GENERAL)
SEE ALSO BIOMEDICAL SYSTEMS AUTOMATED TELEMETERING
AND REMOTE SENSING
SEE ALSO ELECTRONIC STIMULATORS, RAOIOFREQUENCY
CONTROLLED
ROlHL-0465119 Remote stimulation by radio-frequency
transmission (dogs, human)
R01HL-1679I-03 Computer linkage for a dual camera
system
R01HL-18769-04 Studies In survivors of lethal arrhythmias
(human)
BIOMEDICAL SYSTEMS AUTOMATED,
TELEMETERING AND REMOTE SENSING
M POlHL-13738-08 Cardiac assist devices and artificial
hearts
P01HL1373808 0001 Cardiac assist devices and
artificial hearts - Cardiac assist devices (human, sheep)
POlHL-13738-08 0002 Cardiac assist devices and
artificial hearts ■ Total replacement with artificial heart
(calves, sheep, ponies)
ROIHL 13988-07 Elimination of reoperative cardiac
pacemaker surgery (dogs)
** P50HL-17682-D4 0014 Study of Ischemic heart disease •
Myocardial ischemia-Instrumentation and technique (dogs,
baboons)
P50HL-1 7682-04 0015 Study of Ischemic heart disease -
Acute myocardial ischemia and infarction and their
reversibility (dogs, baboons)
BIOMETRY
SEE MATHEMATICS, STATISTICS (INCLUDING BIOMETRY)
BIONOMICS
SEE PSYCHOLOGY, BEHAVIOR ANIMAL
BIOPERIODICITY, BIOLOGICAL CLOCKS
SEE ALSO ENVIRONMENT, ADAPTATION, HIBERNATION
** POlHL-08682-15 0006 Regulation of the cardiovascular
system - Cardiovascular studies of mammalian hibernators
(sciuromorpha)
BIOPERIODICITY, CIRCADIAN RHYTHMS
R01HL03303-2I Factors regulating electrolyte excretion by
the kidney (human, dogs)
ROlHL-05360-19 Cholesterol biosynthesis and its control
In liver (rats)
ROlHL-06975-18 Pathogenesis and prevention of
hypertension (rats)
R01HL-0991M2 Hormonal and dietary modification of
NaCl toxicity (rats) mice)
ROlHL-10612-13 0018 Humoral factors in heart failure
and hypertension - The pathogenesis of experimental renal
hypertension (dogs, rabbits, rats)
ROlHL-10612-13 0019 Humoral factors in heart failure
and hypertension • Pathogenesis of hypertension In the
spontaneous hypertensive rat
ROlHL-11046-12 Renin, angiotensin, steroids. Ions and
blood pressure (human, sheep, rabbits)
ROIHL-13917-20 Secretion and effects of adrenal
hormones (human, rabbits, sheep)
P50HL 14141-05 0002 SCOR for atherosclerosis in
childhood - Intrauterine environment of proband group
(human)
R01HL-I5658-05 Intrarenal regulation of sodium
reabsorption
ROlHL-1679605 Cholesterol regulation by HMG-CoA
reductase (rats, human)
ROlHL-16918-05 Role of steroids In hypertension (human)
ROlHL-17724-03 Oral contraceptives and hypertension
(rats)
P01HL17871-04 0013 Kidney, sodium, cardiac output,
arterioles and hypertension - Perfusion pressure and renal
sodium excretion (rats)
R01HL18730-03 Role of mineralocorticoids in low renin
hypertension (human, rats)
(contd)
BIO
E>p»tim«nt(l naufogenic
Modtl ol sustmnad arteiial
fOlHl 189M 03 0006
hypertension progiim
hyptrltnsion (cats)
ROIHl 1906303 Chol»st«iol and lipoprotein melabolism
(rat hepatocytes)
ROIHL 2W7901 Steroids m adrenal legeneralion
hypertension (rats)
NOIHR ?29?001 Identity and quantity cystic librosis
tactois (human)
BIOPHYSICAL CHEMISTRY (GENERAL)*
Stt Also BIOPHYSICS AND BIOPHYSICAl CHEMISTRY STUDY
SECTION
POIHI 11310 1? 009? Mechanisms ol cardiovascular
disease Structural tunctional relationships ol neuronal
differential alloantigens (mice)
POIHI 11310 12 0098 Mechanisms ol cardiovascular
disease Protein chemistry ol thy 1 and related
synaptosomal proteins (mice)
POIHL 11310 12 0102 Mechanisms ol cardiovascular
disease Cardiac membrane and ion mobility (dogs)
•* ROIHL 13198 21 Blood coagulation Physico chemical
properties (human, cattle)
** ROIHL 22402 01 Heparin biophysical, chemical and
biological aspects (mice, human)
NOIHV 52907 04 Interactions ol platelets with collagens
(human, mammals)
BIOPHYSICS (GENERAL)*
SEE ALSO BIOMEDICAL ENGINEERING
SEE ALSO PHYSICAL PROPERTIES, RHEOLOGY (NOT INCL.
BLOOD)
** P01HL08899 14 0073 Tolerance to respiratory gases in
health and disease ^ Biophysical mechanisms involved in
isobaric gas counterdiffuslon syndrome
** P01HL11310-12 0094 Mechanisms of cardiovascular
disease Physics of pulsatile fluid flow (dogs)
POlHL-1131012 0102 Mechanisms of cardiovascular
disease ■ Cardiac membrane and ion mobility (dogs)
•* POlHL-1131012 9003 Mechanisms of cardiovascular
disease - Core support-biophysical sciences
** R01HL1249410 Continuum mechanics in biophysics
(human, animals)
** P01HL1441407 0004 Environmental influences on
cardiorespiratory and cellular functions Role of diffusion
in gas exchange (chicken egg)
** R0]HL-1449505 Solid and structural mechanics of lungs
(mammals)
POIHL- 15832-06 0005 Chemical-structural predispositions
to lung injury Pulmonary structure and stress-strain
relationships (rats)
ROlHL-17503-03 Vascular bubbles in decompression
sickness (minipig, dog, goat)
R01HL-18676-03 Myocardial sarcomere mechanics (rat)
Energy output and efficiency of left
ROlHL-18933-03
ventricle (dog)
ROlHL-19647-03
ROlHL-20079-02
ROlHL-20105-02
Therapeutic aerosols
Thromboresistant material
Deposition of hygroscopic aerosols in
bronchi (dogs, human, models)
** ROlHL-20749-01 Developing heart -Biophysical aspects
(sheep)
** ROlHL-20750-01 Studies in sickle cell disease (human)
ROlHL-22505-01 Molecular pathology of fibrinogen and
factor XIII (human, animals)
BIOPHYSICS, BIOMECHANICS
P0IHL-06664-I7 0042 Cardiopulmonary function in
remediable vascular disease - Physiologic studies on vein
grafts (dogs)
POlHL-1 1310-12 9003 Mechanisms of cardiovascular
disease - Core support-biophysical sciences
** POlHL-14388-07 0214 Regulation of the circulation in
pathological states - Deformation pattern and stress
analysis of the left ventricle
** POlHL-14388-07 0215 Regulation of the circulation In
pathological states - Left ventricle model in
pathophysiologic states
POlHL-14388-07 0216 Regulation of the circulation in
pathological states - Development and regression of
ventricular hypertrophy (cats, rats)
POlHL-14388-07 0219 Regulation of the circulation In
pathological states Myocardial ischemia and infarction in
animals (dogs)
** R01HL-14854-07 Lung and tissue mechanics (monkeys,
dogs)
P50HL-I9170-02 0006 Harvard pulmonary SCOR -Chronic
diseases of the airways - Mechanism of overdistension
(human, animal)
ROlHL-20163-02 Competitive coronary flow In native and
graft vessels (dog)
** ROlHL-20773-02 Surfactant, pulmonary edema, and lung
mechanics (rabbits)
ROlHL-21095-02 Enzymes of M tuberculosis and
obstructive lung disease (human, rodents)
R01HL-23205-0I Contraction of pulmonary vascular
smooth muscle (cat)
ROlHL-23240-01 Pulmonary vascular muscle metabolism
and contractility (rats, cattle)
43
BIOPHYSICS AND BIOPHYSICAl CHEMISTRY
STUDY SECTION
•• ROllll OI6t)? n Iquilibiij in Ihc libiinORfn libiiii
conversion (human cattle)
•• ROIHI 05556 19 Proteins lipoproteins Sliutluie and
reactivity (chicken, human, diving mammals)
•• ROIHI 05949 18 '
labbits)
•• ROIHI 0/451 16
allostery (human)
ROIHI 08893 14
proteins (human)
ROIHL 09544 I?
(animals)
ROIHL 09739 13
ROIHL 10383 12
Biochemistry of muscle contraction (rats.
Hemoglobin S gelation and hemoglobin
Structure and function of membrane
Biochemistry of contractile proteins
Biophysical studies of proteins (human)
Physical chemical studies of hemoglobins
and erythrocyte (human)
ROIHL 11511 10 Structure of ferritin and it» role in iron
metabolism (horse, rats, human)
ROIHL 11822 10 Biophysical studies of macromolecular
interactions (microorganism, human)
ROIHL 12256 15 Polymerization of sickle cell hemoglobin
(human)
ROIHI 1239510 X-ray study of oxygen-carrying cobalt
complexes
ROIHL 12524 10 Reaction of hemoglobin with ligands and
antibodies (human, carp)
ROIHL 12526 09 Raman spectra of heme proteins and
related molecules
ROlHL-12528-10 NMR relaxation of liquid crystal systems
ROlHL-12760 09 Surface studies of membrane lipids and
proteins
ROlHL-13157-09 Molecular oxygen carriers -Synthesis,
structure, bonding
ROlHL-13164-07 Interaction of the alpha and beta chains
of human hemoglobin
ROIHL 13399-16 Heme protein structure and function
(human, horse, plants, bacteria)
ROlHL-13531-06 Coboglobms -Cobalt substituted myo- and
hemoglobins
ROlHL-1365208
(mushroom)
ROlHL-13909-27
macromolecules
ROlHL-13989-05
structure
ROlHL-1402006
platelets (rabbit)
R01HL14111-07
Metal sites in metalloproteins
Physlochemistry and immunology of
Role of water in respiratiory protein
Characterization of myosin from blood
Cholesteryl esters in membranes and
atherosclerosis (human, swine)
ROlHL-14271-07 Physico-chemical properties of tracheal
mucus (dogs, frogs)
ROlHL-14508-10 Structure and function of respiratory
hemoprotelns
R01HL14509-07 Hypertension-Chemistry and biophysics
of angiotensin
ROlHL-14680-07 Specific enrichment of myoglobins for
carbon 13 NMR (catacea)
ROIHL 14938-06 Contractile proteins of heart muscle
(dogs, rabbits)
R01HL15155-05
ROlHL-15284-06
studies (human
ROlHL-15293-07
Rheology of pulmonary secretions (dogs)
Hemoglobin and myoglobin kinetic
animals)
Sickle cell hemoglobin -Interactions and
aggregation (human)
ROlHL-15378-06 Ultrastructure of antihypertensive
prostaglandins
ROIHL 15391-07 EPR studies on rotational motion of
myosin and actin
ROlHL-15460-06 Molecular adaptation-Hemoglobin
systems of fish (marine)
R0IHL-15627-D6 X-ray and chemical studies of
metalloporphynns
ROlHL-15648-06 Lipid metabolism -Transport by lateral
diffusion (human, rabbit, cattle)
ROlHL-15679-06 Heart and smooth muscle contractile
protein (swine, cattle, rabbits, chickens)
ROIHL 15958-06 X-ray diffraction analysis of thrombin
and neurotoxin
ROlHL-15980-06 Reactions of hemcprotelns and oxygen
(cattle)
ROlHL-16087-05 Structural and dynamic study of model
heme complexes (yeast)
ROlHL-1609305 Functional properties of hemoglobin and
erythrocytes
R01HL-1610r05 Protein-hpid Interaction (bacteria,
models)
ROlHL-16166-05 Structure of alpha-l-antitrvpsin In
relation to emphysema (human)
ROlHL-16474-05 Antiblotlc-ion interactions (model
membranes)
R01HL-16601-05 Structure and function of blood proteins
(human, cattle)
R01HL-1666C-06 Phospholipld-cholesterol and
phospholipidprotein interactions
ROlHL-16678-03 Fluorescent probe studies of heart
muscle proteins (rabbit, dog)
ROlHL-16860-05 Mossbauer studies of respiratory
hemoprotelns
ROlHL-16891-05 The folding of hemoglobin
ROlHL-16927-05 Structure and function of normal and
abnormal hemoglobin (human)
Microcrystallme and crystalline fibrinogen
Thin filament control ol heart contraction
BIO
ROIHI 17411 04 Mokculir iludi<« of red blood cell
iptctrin (human)
ROIHI 1/494 0/ Meihanitm ol liqand binding to
hemoglobin (human)
ROIHI 1/55901 Mructunl elocidition ol hurt
cytochrome C oxidate
ROIHI 1/56/03 lipoprotein cytolytic loiin inltiittion
(Slaphylococcui aureut. mammals human)
ROIHI 1/5/103 Study ol membrane permeability by NMR
lelaialion (human)
ROIHI 1/5/6 04 Role ol sphingomyelin in biomembrantt
and bilayers (rah, other mammals)
' ROIHI 1/826 04 Oxygen delivery to tissue (rat dog)
' ROIHL 1/82804 Kinetic sludic of hemerythiin reactionj
(marine worms)
■ ROIHI 1/8/804 Structural studies ol the human
erythrocyte membrane
* ROIHL 18004 02 Transport through arterial wall
Biophysical aspects (rabbits)
' ROIHL 1804804 Dynamics of artificial and biological
membranes (human)
' ROIHL 1822604 Mechanism of oxygen supply to tissue
(human, animals)
■ ROIHL 1825504 Lipid-protem interactions and calcium
transport (models)
* ROIHL 18256-01 Optical properties of platelets and
erythrocytes (rabbits, dogs, human)
* ROIHL 1827203 Heart adenyl cyclase complex (beef
heart)
* ROlHL-18304 03 FT infrared spectroscopy of heart muscle
energetics (cattle)
* ROIHL 18309-04 Oxygen transport -Hemoglobins with
modified hemes (horse)
* ROIHL 18441 03 Guidelines for polymers acting as elastin
substitutes
* ROIHL 18516 03 Atherosclerosis and the arterial
contractile proteins (pigs, rabbits)
* ROIHL 18533-03
(cattle bacteria)
* R01HL1861203
(cattle)
* ROIHL 18619-03 Transferrin iron binding and transport
properties (chicken, rabbit, human)
* ROlHL-18623 12 Physical chemistry of biologically active
lipids (bacteria, plant, cattle, human)
■* R01HL-18634-03 Quarternary structure of erythro and
chlorocruorins (invertebrates)
'* ROlHL-18660-03
erythrocytes
'* ROIHL 18725-03
process (human)
'* ROlHL-18737-03 Human erythrocyte membrane structure
'* ROlHL-18746-02 Chemical studies on proteollpid
apoproteins (cattle)
** ROlHL-1881804 Stereochemical mechanism of sickling of
hemoglobin S (human)
■* R01HL-188I9-07 Chemical studies on sickle cell
hemoglobin (human)
** ROlHL-18905-04 Acquisition of native conformation of
proteins (human, cattle)
** ROlHL-19065-02
** ROlHL-19095-03
(human)
** ROlHL-19392-03
metalloproteins
** ROlHL-19456-03 Immunoglobulins associated with serum
hyperviscosity (human)
** ROlHL-19459-03 Dynamics of atherogenesis and
lipoprotein formation (human, rabbit)
** ROlHL-19481-03 High field NMR studies of respiratory
proteins (human, horse, fish, microbes)
** ROIHL 1948803 Picosecond laser studies of heme-
protems
** ROlHL-19491-03 Mechanism of Iron storage and
mobilization by ferritin (horse)
** ROlHL-19973-01 Non-mvaslve sickled cell monitor
development (human)
** ROlHL-19982-02 Blood coagulation -Protein- metal ion-llpid
Interactions
** R01HL-20241-02 Shear and area moduli for abnormal red
cell membranes (human)
** ROIHL 20319-02 Assembly, structure and interactions of
fibrin (human)
** R01HL20350-02 Crystal structure of llpids-Cholesterol
** ROlHL-20464-01 Regulation of cardiac and skeletal
muscle contraction (mammals)
" ROlHL-20882-02 Interactions of plasma lipoproteins with
erythrocytes (Rhesus, human)
** ROlHL-2 11 70-01 Molecular structure of human serum
transferrin
** ROlHL-21483-01 Electronic, thermodynamic and kinetics
of hemoglobin
" ROlHL-21757-01 Elastin structure -ONA breathing-
Hemoglobin S gelation
** ROlHL-21791-01 Precipitation of proteins with poly
(ethylene glycol) (human)
" ROlHL-22050-01 Organization of succinic oxidase In heart
** ROlHL-22052-01 Organization of free cholesterol in serum
lipoproteins (human, dogs)
** ROlHL-22081-20 The mechanism of collagen formation
(human, cattle)
(conid)
Neurotransmitter receptors In human
Light-scattering studies of the sickling
Molecular oxygen in biological fluids
Laser spectroscopy of lipoproteins
Spectroscopic studies ol respiratory
•Excludes routine melhodoiogy OR covers only general projects which preclude indexing at the specific level
**Orient€J significantly to above subject
M Grant has subprojcctsdescnbing specific research aspects
See Appendix lor investigator's name and grant number.
BIO
ROlHL-22194-02 Allostcric function of platelet contractile
proteins (human)
" ROlHL-22208-02 Elastin structure, fibrogenesis and
disease (ctiickens. rabbits)
** ROlHL-22270-01 Platelet glycoprotein (human)
ROlHL-22325-01 Thermodynamics in respiratory protein
binding (human, trout)
ROlHL-22432-01 Molecular studies of human erythrocyte
membranes
ROlHL-22461-01 Cardiac tropomyosm and tropomyosin-
action interactions (rabbit)
" ROlHL-2257001 Interactions of sterols in biological
systems (human)
** ROIHL 22654 01 Molecular structure of sickle cell fibers
(human)
ROlHL-2268201 Structure and function of high density
lipoprotein (human, rat)
ROlHL-22771-01 Thrombogenic phospholipid surfaces
(tattle)
** ROIHL 22985 01 Properties and assembly of 2-disk
proteins (human, other species)
** ROlHL-2300301 Bulk-surface distribution of cholesteryl
esters
** ROIHL 23267 01 Rheology and kinetics of hemoglobin S
gelation (human)
" ROlHL-2339201 Membrane binding and transport of
calcium and potassium ionophores
** ROlHL-2361501 Biochemistry of contractile proteins
(chicken, rabbit)
BIOPSY
SEE DIAGNOSTIC TESTS, BIOPSY*
BIOSTATISTICS
SEE MATHEMATICS, STATISTICS (INCLUDING BIOMETRY)
BIOSYNTHESIS OF CARBOHYDRATES
SEE CARBOHYDRATES BIOSYNTHESIS
BIOSYNTHESIS OF FATTY ACIDS
SEE FATTY ACIDS BIOSYNTHESIS
BIOSYNTHESIS OF HEMOPROTEINS
SEE HEMOPROTEINS BIOSYNTHESIS
BIOSYNTHESIS OF HORMONES
SEE ENDOCRINOLOGY, HORMONES BIOSYNTHESIS
BIOSYNTHESIS OF LIPIDS
SEE LIPIDS METABOLISM, LIPOGENESIS
BIOSYNTHESIS OF MEMBRANES
SEE MEMBRANE SYNTHESIS AND RECONSTITUTION
BIOSYNTHESIS OF NEUROTRANSMITTERS
SEE NEUROTRANSMITTERS BIOSYNTHESIS
BIOSYNTHESIS OF NUCLEIC ACIDS
SEE NUCLEIC ACIDS SYNTHESIS
BIOSYNTHESIS OF PEPTIDE-POLYPEPTIDE
HORMONES
SEE ENDOCRINOLOGY, HORMONES BIOSYNTHESIS, PEPTIDE-
POLYPEPTIDE HORMONES BIOSYNTHESIS
BIOSYNTHESIS OF PROTEINS
SEE PROTEINS BIOSYNTHESIS
BIOSYNTHESIS OF STEROIDS
SEE STEROIDOGENESIS
BIOSYNTHESIS OF VITAMINS
SEE VITAMINS BIOSYNTHESIS
BIOTIN
SEE VITAMIN B, BIOTIN
BIOTRANSFORMATION (METABOUSM)
SEE METABOLISM, BIOTRANSFORMATION
BIPHENYLS, HALOGENATED
SEE HALOBENZENES, HALOGENATED BIPHENYLS-TRIPHENYLS
AND ANALOGS
BIROS*
SEE ALSO BODY FLUID BALANCE, IONIC, SALT GUND
** POlHL-0789615 0033 Environmental biorredical research
program - Breathing mechanism in birds
BIRDS, CHICK EMBRYO*
ROlHL-18714-04 Cardiovascular matrix-Morphogenesis
and maturation (human, chick embryo, mammal)
BIROS, PIGEONS*
P50HL-14164-07 0025 A/S SCOR-Comparative and
experimental atherosclerosis - Animal care resource and
laboratory animal medicine unit (monkeys, pigeons)
P50HL14I64-07 0029 A/S SCOR-Comparative and
experimental atherosclerosis - Development of pigeon
substrains
" P50HL-15389-07 0014 Pulmonary SCOR-Hypcrsensitivity
pneumonitis - Fractionation and characterization of pigeon
antigens
BIROS, QUAIL*
ROlHL-15840-02 Sugar-induced heart lesions and vitamin
K deficiency (birds, mammals subhuman)
44
BIREFRINGENCE
SEE OPTICS, BIREFRINGENCE*
BIRTH
SEE PREGNANCY, BIRTH
BIRTH CONTROL
SEE FAMILY PUNNING
SEE FERTILITY
SEE PREGNANCY
BIRTH WEIGHT (ANIMALS)
SEE AGE (ANIMAL), INFANTS, BIRTH WEIGHT
BISBENZYLISOQUINOLINES
SEE OUINOLINES, BISBENZYLISOQUINOLINES
BISHYDROXYCOUMARIN
SEE BENZO-ALPHA PYRONES, BISHYDROXYCOUMARIN
BISULFITES
SEE SULFITES, BISULFITES
BLACK AMERICANS
SEE SOCIAL CROUPS ETHNIC, AMERICANS, BLACK
AMERICANS
BLACK LIPID BILAYER MEMBRANE
SEE BIOLOGICAL TRANSPORT, MEMBRANE MODELS
BLACK LUNG
SEE RESPIRATORY DISORDERS, PNEUMOCONIOSIS
BLACK RACE
SEE SOCIAL GROUPS, RACIAL STOCKS, BLACK RACE
BLASTOCYST
SEE PREGNANCY, EMBRYO-FETUS
BLEOMYCIN
SEE ANTIBIOTICS, BLEOMYCIN
BLOCK ANESTHESIA
SEE SENSORY DEPRESSION, ANESTHESIA CONDUCTION
BLOCKING ANTIBODIES
SEE IMMUNOLOGY, ANTIBODIES, BLOCKING ANTIBODIES
BLOOD
SEE BLOOD AND RE SYSTEM, BLOOD*
BLOOD AND RE DISORDERS, ANEMIA
SEE ALSO IRON CHELATION THERAPY
P60HL-151 57-07 0001 Comprehensive center for sickle
cell disease - Screening program (human)
P60HL1599905 0019 Miami comprehensive sickle cell
center - Fetal-adult hemoglobin switch (mouse, monkey)
ROlHL-16022-05 Determinants of the ventilatory response
to hypoxia (goats, cats)
** ROlHL-161 19-05 Spleen and marrow allografts in
hereditary anemia (mice)
ROlHL-17462-03 Role of glycosphingolipids in platelet
aggregation (rats, human, dogs)
POlHL-17731-04 0010 Physiological basis of pulmonary
disease - Gas exchange kinetics (dogs)
ROlHL-18328-03 Hemoglobin function and tissue
oxygenation (human, dogs)
R0IHL19270-03 Effects of erythropoiesis on platelets and
hemostasis (rats)
ROlHL-22650-01 Regulatory mechanisms of erythropoietin
production (human, rats, mice)
BLOOD AND RE DISORDERS, ANEMIA APLASTIC
NOlHB-62963-03 International bone marrow transplant
registry
NOlHB-62964-03 International bone marrow transplant
registry
ROlHL-06242-18 Kinetic studies of blood (human)
ROlHL-20961-02 Hemoglobin Y-chain genes-Evolution and
inducibility (monkeys, human)
BLOOD AND RE DISORDERS, ANEMIA APLASTIC
CONGENITAL
ROlHL-20899-02 Cellular mechanisms of hemoglobin F
regulation (human)
BLOOD AND RE DISORDERS, ANEMIA
HEMOLYTIC
SEE ALSO BLOOD GROUP INCOMPATIBILITY
** ROlHL-07652-14 Destruction of red blood cells in
hemolytic anemias (human, guinea pigs)
ROlHL-12944-09 Enzymatic and biochemical studies on
blood cells (human)
ROlHL-14131-18 Abnormal hemoglobin syndromes
(human)
R01HL15125-07 Molecular pathology of genetic disorders
in man
P60HL1600505 0022 Comprehensive sickle cell center -
Regulation of erythropoiesis in patients with sickle cell
anemia
R01HL16421-08 Determinants of RBC deformability and
capillary flow (human, mice)
POlHL-16833-04 0011 Hemoglobin and red cell system in
hemoglobinopathies ■ Relationship between hemoglobin and
RBC membrane in sickling cells (human, rats)
ROlHL-18163-04 Red cell membrane effects due to
oxidizing agents
BLO
** POlHL-18208-04 0005 Center for the study of blood cell
rheology ■ RBC deformability and capillary flow
interrelations (human, mice)
ROlHL-19532-01 Oxygen toxicity in the red cell (human)
P60HL-20985-01 0007 Northern California sickle cell
center - Immunohematologic abnormalities in sickle cell
anemia (human)
•* ROlHL-21159-02 Pathophysiological effects of hypoxia
(rats)
ROlHL-2365401 Selected topics on blood transfusion
(rabbits, human)
BLOOD AND RE DISORDERS, ANEMIA
HEMOLYTIC AUTOIMMUNE
R01HL-1003613 Biology of red cell antigen-antibody
reaction (human)
ROlHL-1299409 The Rh complex of red cells (human)
BLOOD AND RE DISORDERS, ANEMIA
HEMOLYTIC CONGENITAL (GENERAL)
SEE ALSO HEMOPROTEINS, HEMOGLOBINOPATHIES
SEE ALSO METABOLIC DISORDERS INBORN, GLUCOSES-
PHOSPHATE DEHYDROGENASE DEFICIENCY
SEE Also MlTAECLIC DISORDERS INBORN,
PHOSPHOGLYCERATE KINASE DEFICIENCY
SEE ALSO METABOLIC DISORDERS INBORN, PYRUVATE
KINASE DEFICIENCY
ROlHL-07449-17 Formation and survival of red blood cells
(human)
ROlHL-12944-09 Enzymatic and biochemical studies on
blood cells (human)
** ROlHL-12972-09 Glutathione deficiency in red cells
(sheep, dogs)
** R01HL-1993302 Membrane and red cell dysfunction In
hemolytic anemia (human)
BLOOD AND RE DISORDERS, ANEMIA
HEMOLYTIC CONGENITAL, EILIPTOCYTOSIS
HEREDITARY
POlHL-18208-04 0005 Center for the study of blood cell
rheology ■ RBC deformability and capillary flow
interrelations (human, mice)
ROlHL-20241-02 Shear and area moduli for abnormal red
cell membranes (human)
BLOOD AND RE DISORDERS, ANEMIA
HEMOLYTIC CONGENITAL, NONSPHEROCYTIC
SEE ALSO BLOOD AND RE DISORDERS, ANEMIA HEMOLYTIC
CONGENITAL, ELLIPTOCYTOSIS HEREDITARY
ROlHL-07449-17 Formation and survival of red blood cells
(human)
BLOOD AND RE DISORDERS, ANEMIA
HEMOLYTIC CONGENITAL, SPHEROCYTOSIS
HEREDITARY (GENERAL)
ROlHL-07449-17 Formation and survival of red blood cells
(human)
R01HL-16421-08 Determinants of RBC deformability and
capillary flow (human, mice)
P01HL-1683304 0011 Hemoglobin and red cell system in
hemoglobinopathies - Relationship between hemoglobin and
RBC membrane in sickling cells (human, rats)
POlHL-18208-04 0001 Center for the study of blood cell
rheology ■ Physiological basis of reversible erythrocyte
shape change (human, firefly)
POlHL-1820804 0005 Center for the study of blood cell
rheology - RBC deformability and capillary flow
interrelations (human, mice)
POlHL-18208-04 0007 Center for the study of blood cell
rheology - RBC membrane protein (human)
R01HL1855103 Spectrin, actin. lipid and red cell
membrane structure
ROlHL-18660-03 Neurotransmitter receptors in human
erythrocytes
ROlHL-20241-02 Shear and area moduli for abnormal red
cell membranes (human)
ROlHL-21404-01 Raman spectroscopy of erythrocyte and
model membranes (human)
** ROlHL-22432-01 Molecular studies of human erythrocyte
membranes
BLOOD AND RE DISORDERS, ANEMIA
HYPOCHROMIC MICROCYTIC
SEE ALSO BLOOD AND RE DISORDERS. ANEMIA
SIDEROBUSTIC
SEE ALSO HEMOPROTEINS, HEMOGLOBINOPATHIES,
THALASSEMIA
ROlHL-06242 18 Kinetic studies of blood (human)
R01HL07139-17 Cardiodynamics and metabolism of
congestive failure (human, dogs)
P60HL1600505 0022 Comprehensive sickle cell center -
Regulation of erythropoiesis in patients with sickle cell
anemia
ROlHL-1667505 Human urinary erythropoietin collection
ROlHL-1816304 Red cell membrane effects due to
oxidizing agents
BLOOD AND RE DISORDERS, ANEMIA
MEGALOBLASTIC
P60HL-16005-05 0022 Comprehensive sickle cell center -
Regulation of erythropoiesis in patients with sickle cell
anemia
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Oriented si(nificantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
(contd)
•lO
BLOOD AND RE DISORDERS, ANEMIA
SIDEROBLASTIC
ROIHI 20000 03 lion ovtiload in homo/ygous beta
IhalasstmK (human)
BLOOD AND RE DISORDERS, BLOOD DISORDERS
(GENERAL)
Sll ALSO BLOOD AND Rt OlSORDtRS. ANiMIA
Sft ALSO BLOOD AND Rt DISORDERS. BONl MARROW
SEE ALSO BLOOD AND RE DISORDERS. HEMORRHAGIC
DISORDERS
SEE ALSO BLOOD AND RE DISORDERS. LEUKOCYTE
DISORDERS
SEE ALSO BLOOD COAGULATION DISORDERS
SEE ALSO BLOOD GROUP INCOMPAIIBIIITY
SEE ALSO BLOOD PLATELETS DISORDERS
SEE ALSO BLOOD PROTEINS DISORDERS
SEE ALSO HEMOPROIEINS. HEMOGLOBINOPATHIES
SEE ALSO HEMOPROTtlNS. HEMOGLOBINURIA. PAROXYSMAL
NOCTURNAL
SEE ALSO HEMOPROTEINS. METHEMOGLOBINEMIA
SEE ALSO KIDNEY DISORDERS. UREMIA
•* ROIHI 1283909 Flow, tiansport and membrane
phenomena in blood (human)
"* ROIHL 1294409 Enzymatic and biochemical studies on
blood cells (human)
ROIHL 1S722 06 Hemorrheology studies related to in vivo
blood (low (human)
POIHL 16833 04 Hemoglobin and red cell system in
hemoglobinopathies
POIHL 16851 04 Human red cell membrane in health and
disease
Human red cell membrane in
Rheology of erythrocyte membrane
M
M
POlHL-16851 04 0001
health and disease
(human, amphiuma)
POIHL 16851 04 0009
health and disease -
Human red cell membrane in
Blood cell properties in circulatory
regulation (dogs, rabbits)
P01HL16851-04 0010 Human red cell membrane in
health and disease • Core facility-Hematology clinic
ROlHL-1782103 Cavitation phenomena near prosthetic
devices
R01HL17881-15 Biosynthesis and degradation of blood
group substances (human, animals)
R01HL'I8163-04 Red cell membrane effects due to
oxidizing agents
P01HL18208-04
rheology
ROlHL-1916302
Atlantic cod
ROlHL-1916403
Atlantic cod
R01HL1917303
Center for the study of blood cell
Piscine erythrocytic necrosis in the
Piscine erythrocytic necrosis in the
Analysis of blood trauma from
microporous oxygenators (human, dogs, rabbits)
ROlHL-2030303 Cholesterol distribution in erythrocyte
membrane (human, animals)
** ROlHL-22219-01 Prostacyclin and peroxides in blood and
membrane disease
BLOOD AND RE DISORDERS, BONE MARROW
SEE ALSO BLOOD AND RE DISORDERS. ANEMIA APLASTIC
R23HL-21212-02 Alveolar macrophage function in
Pseudomonas infection (dgs)
BLOOD AND RE DISORDERS, BONE MARROW,
POLYCYTHEMIA
POlHL-06285-18 0133 Cardiovascular-respiratory
physiology and biochemistry • Decreased uterine blood flow
and fetal development (lambs)
POlHL-0628518 0136 Cardiovascular-respiratory
physiology and biochemistry - Fetal microcirculation in
utero (rabbits, lambs)
** P01HL-11310I2 0095 Mechanisms of cardiovascular
disease - Blood and transfusion disorders (human, rats,
monkeys)
POlHL-14985-07 0003 Adaptation to hypoxia - Hypoxia
and oxygen transport (human, dogs)
" P01HL14985-07 0013 Adaptation to hypoxia ■ Chronic
mountain sickness (men)
ROlHL-16656-06
(dogs)
ROlHL-2 11 59-02
(rats)
ROlHL-22650-01
Left ventricular function in exercise
Pathophysiological effects of hypoxia
Regulatory mechanisms of eivthropoietin
production (human, rats, mice)
BLOOD AND RE DISORDERS, HEMORRHAGIC
DISORDERS
SEE ALSO BLOOD COAGUUTION DISORDERS
SEE ALSO BLOOD PUTELETS DISORDERS
SEE ALSO CARDIOVASCUUR DISORDERS. HEMORRHAGE
SEE ALSO NASAL DISORDERS. EPISTAXIS
** ROlHL-01601-30 Blood coagulation and hemorrhagic
disease (horseshoe crabs)
** ROlHL-01661-27 Hemostatic mechanisms (human)
ROlHL-02212-23 Coagulation of blood (human)
** ROlHL-02254-23 Blood coagulation and hemorrhagic
disease (human, animals)
** ROlHL-10582-12 Thrombosis and hemostasis-Analysis,
methods and standards (human, cattle, venom)
** R01HL13629-08 Hemorrhagic diseases (human)
ROlHL-14595-07 Primary disorders of platelet function
(human, rats)
Collection, function and transfusion of
The role of leukocytes in thrombotic
45
ROIHI 15335 06 The nature of the collagen plattitt
Milviaction (aniiniM
ROIIU 1/462 03 Role ol glycotphingolipidt in plll«l«l
aggregation (i»t\. human, dogi)
ROlHt 21403 02 Blood clotting kinetics studied by
iddiuiminunoiis^ny (huinon)
BLOOD AND RE DISORDERS, LEUKOCYTE
DISORDERS
SEE Also IMMUNIIY, IMMUNOIOGICAI UNRf SPONSIVf NFSS
SEE ALSO MtlABOlIC DISORDERS INBORN. ANGIONEUROTIC
EDEMA (HEREDITARY)
SEE ALSO METABOLIC DISORDERS INBORN. CHEOIAK HIGASHI
SYNDROME
ROIHL 1666006 Phospholipid cholesterol and
phospholipid protein interactions
ROIHL 17437 03 Perfusion lung'-Role ol traumatized
leukocytes (dogs, human)
ROIHL 20807 02 Detection of familial hypercholesterolemia
(human)
BLOOD AND RE DISORDERS, LEUKOCYTE
DISORDERS, AGRANULOCYTOSIS
NOIHB 6297002 Collection, function and transfusion of
granulocytes
NOIHB 62973 05
granulocytes
•* R01HL14739-06
disease (human, dogs)
P01HL1857603 0007 Thrombosis research program
protect Relationships between coagulability and
thrombosis (human, animals)
BLOOD AND RE DISORDERS, LEUKOCYTE
DISORDERS, LEUKOCYTOSIS
ROlHL-1568505 Hemopoietic regulators produced in cell
culture (human, animals)
POlHL-1864603 0006 Studies basic to heart
transplantation - Reduction or elimination of existing
presensitization (human, animals)
BLOOD AND RE DISORDERS, LEUKOCYTE
DISORDERS, LEUKOPENIA
SEE ALSO BLOOD AND RE DISORDERS. LEUKOCYTE
DISORDERS, AGRANULOCYTOSIS
** ROlHL-06242-18 Kinetic studies of blood (human)
ROlHL-15647-06 Hematopoietic studies of cyclic
hematopoiesis (dogs)
P60HL-17265-04 0009 Community blood resource center
support Research -Developing granulocyte transfusion
therapy (human, rabbit)
R23HL-2121202 Alveolar macrophage function in
Pseudomonas infection (dgs)
BLOOD AND RE DISORDERS, LEUKOCYTE
DISORDERS, PHAGOCYTE DYSFUNCTION
(GENERAL)
** P60HL-16005-05 0020 Comprehensive sickle cell center -
Studies of the immunologic defect in sickle cell anemia
(human)
R23HL19584-01 Alveolar macrophage responses to toxic
particle exposure (guinea pigs, human)
BLOOD AND RE DISORDERS, MAST CELL
HYPERPLASIA
•* POlHL-14985-07 0010 Adaptation to hypoxia - Pulmonary
mast cell (animals)
BLOOD AND RE DISORDERS, SPLENIC
DISORDERS
R01HL-19430-03 Congenital heart malformations and
situs inversus (mice)
ROlHL-2008602 Circulatory control of splenic function
(rats)
BLOOD AND RE DISORDERS, SPLENIC
DISORDERS, SPLENOMEGALY
** ROlHL-18997-02 Ischemic therapy in experimental
hypersplenism (rats, dogs)
ROlHL-20086-02 Circulatory control of splenic function
(rats)
BLOOD AND RE DISORDERS CHEMOTHERAPY
SEE ALSO BLOOD AND RE SYSTEM PHARMACOLOGY
SEE ALSO BLOOD COAGULATION. ANTICOAGUUNTS
SEE ALSO BLOOD COAGULATION, FIBRINOLYTIC AGENTS
SEE ALSO BLOOD COAGUUTION. HEMOSTATICS
SEE ALSO HEMOPROTEINS. HEMOGLOBINOPATHIES, SICKLING
INHIBITORS
SEE ALSO IRON CHELATION THERAPY
NOlHB-729 16-02 Crisis and pain symptom prophylaxis by
oral zinc therapy (human)
ROlHL-01601-30 Blood coagulation and hemorrhagic
disease (horseshoe crabs)
R01HL-02799-22 Abnormal hemoglobins (human)
P01HL-07896-15 0057 Environmental biomedical research
program - Effects of dipyridamole and aspirin on
decompression thrombocytopenia (human)
ROlHL-1058212 Thrombosis and hemostasis-Analysis,
methods and standards (human, cattle, venom)
P01HL11414-11 0004 Thrombosis and atherosclerosis
program - Platelet function and nonthrombogenic surfaces
(human)
BLO
POIHI II4I4 II 0033 Thiombo-.r. •ml .li.riuv l.iojii
piogrnrn Human couinarin induced prothromliin
ROIHt 129/2 09 Glutathione delirieniy in red callt
(iheep. dog%)
POIHL 13/38 08 0003 Cardiac ai>iit dtvicet and
artificial hearts Palhophyiiological •tfectt of the artilirial
heart (calves)
•• ROIHL 13/54 08 Postoperative Ihiomboembolism in
surgical patients (human)
P60HL 15158 0/ 0011 Compreheniive tickle cell center
Clinical services Adult patients
P60HI 15169 05 0018 Support for center lor sickle cell
disease Studies on sickle cell disease (human rats,
dogs)
P60HL 15170 05 0001 Support lor center lor sickle cell
anemia Adult clinical services
POIHL 15486 06 0006 Studies on thrombosis Clinical
investigation unit
ROIHL 15593 05 Prolonged extracorporeal cardiopulmonary
support (rats, sheep, rabbits)
•* POIHL 15596 05 0001 Coagulation, fibrinolysis,
hemostasis and hepatitis Defibrination (human)
M P60HL 15999 05 Miami comprehensive sickle cell center
** P60HL 15999 05 0008 Miami comprehensive sickle cell
center Cyanate effect on host defense Cellular and
humoral (human, guinea pig. rabbits)
ROIHL 1637504 Investigation ol hemoglobin S properties
(human)
M POIHL 1743005 Control ol coagulation
** POIHL 17430 05 0001 Control ol coagulation Porcine
von Willebrand's disease
ROIHL 18012 04 Cellular defects in nocturnal
hemoglobinuria (human)
M POIHL 1857603 Thrombosis research program project
POIHL 18576 03 0013 Thrombosis research program
project Early warning and monitoring lest systems in
thrombotic disease (human)
ROlHL-1881503 Surgical vascular disorders (human,
dogs)
** ROlHL-18819-07 Chemical studies on sickle cell
hemoglobin (human)
ROlHL-2092001 Control of hemoglobin synthesis (baboon)
R23HL-21212 02 Alveolar macrophage function in
Pseudomonas infection (dgs)
BLOOD AND RE DISORDERS CONGENITAL
(HEREDITARY)
SEE ALSO BLOOD AND RE DISORDERS. ANEMIA APLASTIC
CONGENITAL
SEE ALSO BLOOD AND RE DISORDERS. ANEMIA HEMOLYTIC
CONGENITAL (GENERAL)
SEE ALSO BLOOD COAGULATION DISORDERS
SEE ALSO BLOOD PROTEINS DISORDERS CONGENITAL
SEE ALSO HEMOPROTEINS, HEMOGLOBINOPATHIES
SEE ALSO IMMUNOPATHOLOGY, IMMUNOLOGIC DEFICIENCY
DISORDERS
R01HL-0ie48-31 Blood coagulation and hemophilia (dogs.
swine)
ROlHL-022 12-23 Coagulation of blood (human)
R01HL02254-23 Blood coagulation and hemorrhagic
disease (human, animals)
ROlHL-04366-19 Plasminogen -Activation and structure-
function relations (mammals, birds)
** ROlHL-05168-19 Inhomogencity of hemoglobin types
(human)
** R01HL-05351-18 Blood group antigens and antibodies
(human, rabbits, sheep)
P01HL06314-17 0047 Immunologic mechanisms in
cardiovascular disease - Role of intravascular coagulation
(human, animals)
ROlHL-0916313 Control mechanisms in hemostasis
(human)
** R01HL12944-09 Enzymatic and biochemical studies on
blood cells (human)
** R01HL13585-05 Heterogeneity of NADH methemoglobin .
reductase (human)
ROlHL-14131-18
(human)
Abnormal hemoglobin syndromes
Primary disorders of platelet function
R01HL14595-07
(human, rats)
ROlHL-15647-06 Hematopoietic studies of cyclic
hematopoiesis (dogs)
R01HL-16U9-05 Spleen and marrow allografts in
hereditary anemia (mice)
ROlHL-17752-03 Purified human clotting factor IX-
Immunologic studies (human)
R01HL18507-03 Clinical studies of Fletcher factor
(human)
ROlHL-18586-03 Role of platelet lipids in hemostasis and
thrombosis (human)
ROlHL-19272-03 Studies on the Passovoy factor (human)
ROlHL-19646-03 An immunologic study of hemoglobin
variation in man
ROlHL-20751-01 High speed liquid chromatography of
hemoglobins (human)
ROlHL-20925-01 The acetylation of fetal hemoglobin
(human)
POlHL-2101602 0012 Sickle cell anemia and other
hemoglobinopathies - Stimulation of Hb F synthesis in a
permanent cell line
R23HL-21428-02 Expression of human globin in
thalassemia (human)
(contd)
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
**0nented significantly to at»ve subject.
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number
BLO
" ROIHL 21487-01 Molecular characterization of
Glanzmann's thrombasthenia (human)
" R01HL-2I975-01 Studies on normal and abnormal factor
IX (human, dogs, cows)
R23HL-22621-01 Blood cell-mediated pulmonary (human)
BLOOD AND RE DISORDERS DIAGNOSIS (INCL
EXAMS)*
SEE ALSO BLOOD COAGUUTION TESTS*
SEE ALSO BLOOD (HEMATOLOGIC) TESTS*
ROlHL-02212-23 Coagulation of blood (human)
** P60HL-15157-07 0001 Comprehensive center for sickle
cell disease - Screening program (human)
*• P60HL-15158-07 0004 Comprehensive sickle cell center -
Expression of abnormal hemoglobin synthesis in the
neonate and young child
P60HL-15I60-07 0009 Center for sickle cell disease ■
Natural history of sickle cell disease (human)
** P6aHL15160-07 0012 Center for sickle cell disease ■
Core laboratories
** P60HL1516007 0013 Center for sickle cell disease -
Immunochemical diagnosis of hemoglobinopathies (infants)
** P60HL-1516007 0017 Center for sickle cell disease -
Demonstration-Education, screening, counseling, patient
care
** P60HL-1516207 0011 Comprehensive sickle cell center -
Core program-Genetic counseling and diagnostic screening
** P60HL15162-07 0018 Comprehensive sickle cell center -
Biochemical and genetic studies of sickle cell anemia
(human)
** P60HL-1516807 0001 Comprehensive sickle cell disease
center - Screening program (human)
P60HL1516807 0010 Comprehensive sickle cell disease
center - Sickle cell center project (children)
M POlHL-1548606 Studies on thrombosis
POlHL-15486-06 0001 Studies on thrombosis - Studies on
chemistry of fibrinogen (human, dogs)
POlHL-15486-06 0002 Studies on thrombosis -
Characterization of antisera to fibrinopeptlde B (human,
rabbits)
** P01HL15596-05 0001 Coagulation, fibrinolysis,
hemostasis and hepatitis - Defibrination (human)
ROlHL-15722-06 Hemorrheology studies related to in vivo
blood flow (human)
M P60HL15999-05 Miami comprehensive sickle cell center
** P60HL-15999-05 0004 Miami comprehensive sickle cell
center - Education, screening and counseling
** P60HL-16005-05 9001 Comprehensive sickle cell center -
Core laboratory and counseling (human)
** P60HL16008-0G 0011 Wayne State University
comprehensive sickle cell center ■ Education, screening and
counseling
** P60HL-16008-06 0020 Wayne State University
comprehensive sickle cell center - Genetic and physiological
studies of sickle cell anemia (human)
** POIHL-16387-04 0005 The blood vessel and
thrombogenesis - Fluid engineering considerations in
thrombogenesis
P01HL-I7419-04 0001 Studies on mechanisms of
hemostasis - Structure and metabolism of fibrinogen
(human)
M POlHL-17430-05 Control of coagulation
** POlHL-17430-05 0001 Control of coagulation - Porcine
von Willebrand's disease
** POIHL 17430-05 0005 Control of coagulation - The
activation of prothrombin (human, cattle, dogs)
** POlHL-17430-05 0006 Control of coagulation - Activation
fragments of prothrombin in vitro and in vivo (human,
dogs, cattle)
** R01HL-I7769-03 New methods of studying blood
coagulation kinetics
ROIHL 18012-04 Cellular defects in nocturnal
hemoglobinuria (human)
M P01HL18576-03 Thrombosis research program project
*' P01HL18576-03 0013 Thrombosis research program
proiect Early warning and monitoring test systems in
thrombotic disease (human)
ROlHL-1872503 Light-scattering studies of the sickling
process (human)
ROIHL 20856-02 Platelet transfusions-Usage and
complications (human)
M P60HL-2098501 Northern California sickle cell center
** P60HL 20985-01 0009 Northern California sickle cell
center ■ Patient services (children, adults)
** P60HL-20985-01 0010 Northern California sickle cell
center Prenatal diagnosis of sickle cell anemia
P01HL2101602 0017 Sickle cell anemia and other
hemoglobinopathies ■ The hereditary clinic core
** P01HL-22I63-01 0002 Surface fhrombogenesis-
Mechanisms and prevention - Laser-scattering detection of
microemboli in blood flow (baboons)
P60HL-2328201 9001 Comprehensive hospital/community
sickle cell center ■ Core -Institutionalization of education,
screening and counseling
BLOOD AND RE DRUGS (GENERAL)
SEE ALSO BLOOD AND RE SYSTEM, HEMATOPOIETIC FACTORS
SEE ALSO BLOOD COAGULATION, ANTICOAGUUNTS
SEE ALSO BLOOD COAGUUTION. ANTIFIBRINOLYTIC AGENTS
SEE ALSO BLOOD COAGUUTION, FIBRINOLYTIC AGENTS
SEE ALSO BLOOD COAGUUTION, HEMOSTATICS
SEE ALSO BLOOD SUBSTITUTES
46
SEE ALSO HEMOPROTEINS, HEMOGLOBINOPATHIES, SICKLING
INHIBITORS
ROlHL-22338-01 Platelet adhesion and aggregation in a
flow chamber (human)
BLOOD AND RE SYSTEM, BLOOD*
SEE ALSO BLOOD AND RE SYSTEM, HEMATOLOGY
SEE ALSO BLOOD AND RE SYSTEM, HEMATOPOIESIS
SEE ALSO BLOOD AND RE SYSTEM, HEMATOPOIETIC TISSUE
SEE ALSO BLOOD AND RE SYSTEM, IMMUNOHEMATOLOGY
(GENERAL)
SEE ALSO BLOOD CELLS
SEE ALSO BLOOD COAGULATION
SEE ALSO BLOOD GROUPS
SEE ALSO BLOOD PRESERVATION
SEE ALSO BLOOD PROTEINS
SEE ALSO BLOOD TOXICOLOGY
SEE ALSO BLOOD TRANSFUSION
SEE ALSO CARDIOVASCUUR FUNCTION, BLOOD CIRCUUTION
DYNAMICS (GENERAL)
** POlHL-03174-23 0010 Mechanisms of acute vascular
reaction to in|ury - Search for mutagens in the human
blood (bacteria, animals)
** P01HL14414-07 0014 Environmental Influences on
cardiorespiratory and cellular functions - Temperature and
acid-base status in tissues, cells, and subcellular system
*' POIHL 15596-05 0016 Coagulation, fibrinolysis,
hemostasis and hepatitis - Hepatitis-B antigen in whole
blood, plasma and plasma fractions (human, monkeys)
** ROlHL-16921-05 Synthetic hydrogels as blood tolerable
materials
ROlHL-22406-01 Isobanc vascular bubbles and
decompression sickness (goats, models)
BLOOD AND RE SYSTEM, BLOOD, PLASMA
POlHL-06835-17 0045 Cardiovascular disease ■ Pressure-
volume-renin relationship in human hypertension
P01HL06835-17 0046 Cardiovascular disease • Renin
activity during salt depletion in essential hypertension
(human)
ROlHL-13198-21 Blood coagulation-Physico-chemical
properties (human, cattle)
POlHL-13262-07 0018 Arterial wall in atherosclerosis -
Vasoactive factors of human plasma
P60HL-15I60-07 0014 Center for sickle cell disease -
Replacement therapy of opsonin deficiency in sickle cell
anemia (children)
** POlHL-15596-05 0016 Coagulation, fibrinolysis,
hemostasis and hepatitis - Hepatitis-B antigen in whole
blood, plasma and plasma fractions (human, monkeys)
ROlHL-16346-09 Enzyme assay for blood clotting (human)
ROlHL-16445-05 Regulation of plasma protein
biosynthesis (rats, rabbits)
ROlHL-17487-04 Adrenergic-vasoregulation interactions in
hypertension (human)
ROlHL-17847-04 Cardiovascular and renal functions of
marmots
P50HL-18828-03 0003 Specialized center of research in
thrombosis ■ Structure and function of plasma coagulation
inhibitors (human)
ROlHL-19320-03 Angiotensin neuropharmacology-
Relationship to sodium
ROlHL-20218-02 Fibrinogen catabolism and intravascular
coagulation (human)
ROlHL-20301-02
human blood
ROlHL-20558-02
and drugs
ROlHL-21094-01
(dogs)
ROlHL-21139-02
ROlHL-21239-02
Genetics of glycosyitransferases In
Cardiac electrophysiology-Effects of ions
Arterial baroreceptors and renal function
Molecular biology of factor XIII (human)
Isolation and mechanism of action of
thromboxane A2 (human, rabbits)
ROlHL-21540-02 Specific inhibitors of coagulation and
fibrinolysis (rats, rabbits, dogs)
ROlHL-21764-01 Ultramicroanalysis of prostaglandins and
related compounds (rats)
ROIHL-22051-01
release (human)
ROlHL-22273-01
(rats)
ROlHL-22627-01
Role of angiotensin II in vasopressin
Oral and lung absorption of nitroglycerin
An inhibitor of platelet adhesion to
artificial organs (human)
ROlHL-22996-01 Venom proteases-Action on plasma
protease inhibitors (human)
ROlHL-23726-01 Treatment of ventricular arrhythmias with
propranolol (human)
BLOOD AND RE SYSTEM, BLOOD, SERUM
SEE ALSO IMMUNOLOGY, ANTIBODIES, IMMUNE SERA
SEE ALSO IMMUNOLOGY, SEROLOGY*
ROlHL-06924-16 Humoral and metabolic aspects of
cardiac function (mammals, non-human, human)
P01HL-08682-15 0006 Regulation of the cardiovascular
system ■ Cardiovascular studies of mammalian hibernators
(sciuromorpha)
R01HL13885-08 0007 Cystic fibrosis and pulmonary
disease ■ Alveolar macrophage defense mechanism
(human, rabbits)
ROlHL-13885-08 0008 Cystic fibrosis and pulmonary
disease - Pseudomonas specific activation of alveolar
macrophages (human, rabbits)
BLO
ROlHL-13885-08 0009 Cystic fibrosis and pulmonary
disease ■ Respiratory mucus glycoproteins (human, rabbits)
POIHL- 178 12-04 0004 Thrombosis and plasma proteins -
Serum-platelet interaction (human)
ROlHL-1906603 Synthesis and evaluation of
prostaglandin metabolites (guinea pigs)
P50HL19157-02 0007 Studies in cystic fibrosis and
bronchiolitis - Analysis of cystic fibrosis factors (human)
R23HL-21083-02 Pharmacokinetics of digoxin and digitoxin
in humans (rats)
R23HL-21411-02 Control of extracellular lysosomal
hydrolase levels (rats)
R23HL-2257501 Factors modifying cardiac digoxin effects
and content (dogs, cats)
NOlHR-72922-01 Cystic fribrosis factor identicalion and
quantification (human)
NOlHR-72923-01 Cystic fibrosis factor identification and
quantification (human)
BLOOD AND RE SYSTEM, BLOOD
FRACTIONATION
SEE ALSO BLOOD TREATMENT, LEUKAPHERESIS
SEE ALSO BLOOD TREATMENT, PUSMAPHERESIS
** ROIHL- 1388 1 -08 The American Red Cross National
Fractionation Center
" POlHL-15596-05 0007 Coagulation, fibrinolysis,
hemostasis and hepatitis - Structural studies and
fractionation of urokinase (human)
** POlHL-15596-05 0008 Coagulation, fibrinolysis,
hemostasis and hepatitis - Structural studies and
fractionation of antihemophilic factor (human)
** P01HL15596-05 0016 Coagulation, fibrinolysis,
hemostasis and hepatitis ■ Hepatitis-B antigen in whole
blood, plasma and plasma fractions (human, monkeys)
" POlHL-1559605 0020 Coagulation, fibrinolysis,
hemostasis and hepatitis ■ Affinity chromatography
P60HL-1 5996-06 0010 Cincinnati comprehensive sickle
cell center - Whole blood viscosity in sickle cell anemia
(human)
P60HL-17265-04 0001 Community blood resource center
support - Demonstration and evaluation
ROIHL-19946-03 Reduction of iron overload in
thalassemia (children, rabbits, dogs, monkeys)
** ROlHL-20788-02 Preservation of human platelets for
transfusion
ROlHL-208 18-02 Platelet storage at 22 degrees C
(human)
P60HL-20985-01 0004 Northern California sickle cell
center Characterization of irreversibly sickled cells
(human)
ROlHL-21791-01 Precipitation of proteins with poly
(ethylene glycol) (human)
BLOOD AND RE SYSTEM, BONE MARROW
SEE ALSO BLOOD AND RE SYSTEM, HEMATOPOIHIC TISSUE
SEE ALSO BLOOD CELLS, ERYTHROBUSTS AND ERYTHROIO
STEM CELLS
POlHL-1131012 0095 Mechanisms of cardiovascular
disease - Blood and transfusion disorders (human, rats,
monkeys)
** P01HL18208-04 0003 Center for the study of blood cell
rheology - Bone marrow microcirculation (rats, mice)
P01HL18208-04 0005 Center for the study of blood cell
rheology - RBC deformability and capillary flow
interrelations (human, mice)
ROlHL-19933-02 Membrane and red cell dysfunction in
hemolytic anemia (human)
ROlHL-20961-02 Hemoglobin Y-chain genes -Evolution and
inducibility (monkeys, human)
ROlHL-23736-04 Sickle cell anemia and hemoglobin
synthesis (monkeys)
BLOOD AND RE SYSTEM, BONE MARROW
TRANSPLANTATION
** NOlHB-6296303 International bone marrow transplant
registry
** NOIHB-62964-03 International bone marrow transplant
registry
POlHL-06314-17 0066 Immunologic mechanisms in
cardiovascular disease - Sensitization, cell-mediated
cytotoxicity, role of lymphocytes (human, mice)
POlHL-13108-09 0016 Clinical heart transplantation ■
Total lymphoid irradiation for immune response (dogs)
R01HL13987-04 Transplantation of the lung (dogs)
ROlHL-15647-06 Hematopoietic studies of cyclic
hematopoiesis (dogs)
** ROlHL-16119-05 Spleen and marrow allografts in
hereditary anemia (mice)
P60HL-17265-04 0006 Community blood resource center
support - Research-Evaluation of platelet transfusions
(human, dog)
P60HL17265-04 0008 Community blood resource center
support - Research-Blood genetic markers as biological
probes (human)
ROlHL-19333-03 Hematopoietic chimerism (mice, monkey)
BLOOD AND RE SYSTEM, HEMATOLOGY
SEE ALSO BLOOD AND RE SYSTEM, BLOOD*
SEE ALSO BLOOD AND RE SYSTEM. IMMUNOHEMATOLOGY
(GENERAL)
SEE ALSO BLOOD (HEMATOLOGIC) TESTS*
SEE ALSO HEMATOLOGY STUDY SECTION
(contd)
•Excludes routint methodology OR covers only general proiecls which preclude indexing at the specific level
**Oriented significantly to above subject
M Grant has subprojects describing specific research aspects
See Appendix for investigator's name and grant number.
BIO
POIHI 08899 14 0018 Toltttnci to («>pli«tory |ius in
hMlth ind dijtis* Ettccts o( rfjplratoiy |is«i it
titrtm* prtssuits (human)
" ROIHI 10!>82 1? Thiombosij (nd hemostasis Analysis,
methods and standards (human, cattla. venom)
" POIHL 13738 08 0004 Caidiac assist devices and
aititicial hearts Hematological evaluation a( prosthetic
materials (calves)
KOHL 16008 06 0009 Wayne State University
comprahtnsive sickle cell center Natural history of sickle
cell anemia (human)
ROIHL I62M0S Pathogenesis ot bubble and clot
toimation (lish)
** POIHI 168SI 04 0010 Human ted cell membrane in
health and disease Core facility Hematology clinic
P60HL U26504 0010 Community blood resource center
support Blood resources educational program
" ROIHI 1740204 Mechanism ot contact activation ot
intrinsic clotting (human)
ROIHL 20106 02 Coupling ot platelet contractile proteins
to librin (human)
ROIHI 2078802 Preservation ot human platelets tor
transfusion
ROIHL 22603 01 Trace metals, vascular activity and
hypertension (rats)
BLOOD AND RE SYSTEM, HEMATOPOIESIS
** ROIHL 15647-06 Hematopoietic studies of cyclic
hematopoiesis (dogs)
** P50HL- 1882803 0009 Specialized center ot research in
thrombosis Platelet formation and megakaryocyte cell
biology (guinea pig, human)
** ROIHL 1933303 Hematopoietic chimensm (mice, monkey)
ROlHL-2008602 Circulatory control of splenic function
(rats)
ROIHL 2090202 Studies on marginal band system of
erythrocytes (amphibians, reptiles, fish)
BLOOD AND RE SYSTEM, HEMATOPOIESIS,
ERYTHROPOIESIS
ROlHL-01601-30 Blood coagulation and hemorrhagic
disease (horseshoe crabs)
** ROlHL-03357-21 Humoral control of blood cell formation
and release (rats, mice)
•* ROlHL-04612-20 Feedback between red cell production
and oxygen transport (rabbits, rats)
*• R01HL07449-17
(human)
M P01HL-08899U
and disease
** ROlHL-1056712 Erythropoietin-Immunoassay and
characterization (dogs)
R01HL13237-09 Erythrocytes during early development
(human, animals)
ROlHL-15647-06 Hematopoietic studies of cyclic
hematopoiesis (dogs)
** P60HL15999-05 0019 Miami comprehensive sickle cell
center ■ Fetal-adult hemoglobin switch (mouse, monkey)
P60HL-1 5999-05 0021 Miami comprehensive sickle cell
center ■ Diphosphonates-Eiythrocyte calcium loading,
maturation (human, chick embryo)
** P60HL-16005-05 0013 Comprehensive sickle cell center -
Study of regulation of eiythropoiesis in vitro (human, rat,
hamster, rabbit)
** P60HL-16005-05 0022 Comprehensive sickle cell center ■
Regulation of erythropoiesis in patients with sickle cell
anemia
R01HL16580-04 Mathematical models for studying sickle-
cell disease
** R01HL16654-06
(human)
ROlHL-16675-05
ROlHL-18186-04
Formation and survival of red blood cells
Tolerance to respiratory gases in health
Regulation in developing erythroid cells
Human urinary erythropoietin collection
Cardiac allografts in autologous
radiation chimeras (rats, dogs)
ROlHL-19068-03 Changes in membrane properties during
erythropoiesis (chick embryo)
ROlHL-19270-03 Effects of erythropoiesis on platelets and
hemostasis (rats)
ROlHL-19933-02 Membrane and red cell dysfunction in
hemolytic anemia (human)
ROlHL-20300-02 Histone H5 and avian erythropoiesis
(chickens, rabbits)
ROlHL-20913-02 Cell culture studies of
hemoglobinopathies (human)
ROlHL-20922-02 Control of human fetal hemoglobin
synthesis
ROlHL-21683-02 Purification of erythropoietin (human)
ROIHL-2170102 Purification of erythropoietin (human)
** ROlHL-22650-01 Regulatory mechanisms of erythropoietin
production (human, rats, mice)
ROlHL-24048-01 Regulation of hemoglobin synthesis in
chick embryos
BLOOD AND RE SYSTEM, HEMATOPOIESIS,
LEUKOPOIESIS
** ROlHL-03357-21 Humoral control of blood cell formation
and release (rats, mice)
ROlHL-15647-06 Hematopoietic studies of cyclic
hematopoiesis (dogs)
4/
BLOOD AND RE SYSTEM, HEMATOPOIETIC
FACTORS
SI I ALSO BLOOD AND Rf SYSTEM, RE SIIMUIAIING
FACTORS
SEE Also HIOOD COAGUIAIION. IHROMBOPOIESIS
STIMUIATINC FACIORS
ROIHI 2019/ 02 Maintenance and repair of vascular
endothelium (human, animals)
ROIHI 21303 02 Collagen synthesis by cuMured human
vasculai cells
BLOOD AND RE SYSTEM, HEAAATOPOIETIC
FACTORS, ERYTHROPOIETIC INHIBITORS
ROIHI 21686 02 Purification of erythropoietin (human)
BLOOD AND RE SYSTEM, HEMATOPOIETIC
FACTORS, ERYTHROPOIETIN
SEE ALSO VITAMIN B12
*• NOIHB 82924 00 Source of human urinary erythropoietin
** NOIHB 82926 00 Source ot human urinary erythropoietin
ROIHL 03357 21 Humoral control of blood cell formation
and release (rats, mice)
** ROIHL 04612 20 Feedback between red cell production
and oxygen transport (rabbits, rats)
R01HL07449 17 Formation and survival of red blood cells
(human)
** ROIHL 10567 12 Erythropoietin- Immunoassay and
characterization (dogs)
** ROIHL 1088013 Purification of human erythropoietin (or
research use
ROIHL 14637-05 Thrombopoietin ■Immunoassay and
characterization (mice)
" P60HL-151 7005 0017 Support for center for sickle cell
anemia - Control of hemoglobulin synthesis (human)
R01HL15647-06 Hematopoietic studies of cyclic
hematopoiesis (dogs)
** ROlHL-1568505 Hemopoietic regulators produced in cell
culture (human, animals)
P60HL-16005-05 0013 Comprehensive sickle cell center •
Study of regulation of erythropoiesis in vitro (human, rat,
hamster, rabbit)
" P60HL-1600505 0022 Comprehensive sickle cell center -
Regulation of erythropoiesis in patients with sickle cell
anemia
** R01HL16675-05 Human urinary erythropoietin collection
" POlHL-1820804 0003 Center for the study of blood cell
rheology - Bone marrow microcirculation (rats, mice)
ROlHL-2091202 Control on non-alpha chain synthesis in
thassemic mice
ROlHL-20961-02 Hemoglobin Y-chain genes-Evolution and
Inducibility (monkeys, human)
** ROlHL-21676-02 Purification and properties of
erythropoietin (human)
** ROlHL-21683-02 Purification of erythropoietin (human)
** ROlHL-21686-02 Purification of erythropoietin (human)
** ROlHL-21692-02 Purification of erythropoietin (human)
** ROlHL-21701-02 Purification of erythropoietin (human)
•* ROlHL-22650-01 Regulatory mechanisms of erythropoietin
production (human, rats, mice)
BLOOD AND RE SYSTEM, HEAAATOPOIETIC
TISSUE
SEE ALSO BLOOD AND RE SYSTEM, BONE MARROW
SEE ALSO BLOOD AND RE SYSTEM, SPLEEN
SEE ALSO BLOOD CELLS, HEMATOPOIETIC STEM CELLS
(GENERAL)
ROlHL-209 12-02 Control on non-alpha chain synthesis in
thassemic mice
BLOOD AND RE SYSTEM,
IMMUNOHEMATOLOGY (GENERAL)
ROlHL-022 54-23 Blood coagulation and hemorrhagic
disease (human, animals)
ROlHL-03424-21 Formation and properties of prothrombin
derivatives (human, animals)
ROlHL-07652-14 Destruction of red blood cells in
hemolytic anemias (human, guinea pigs)
R01HL08399-15 Platelet injury in infections and allergic
diseases (human)
** ROlHL-10036-13 Biology of red cell antigen-antibody
reaction (human)
ROlHL-1056712 Erythropoietin-Immunoassay and
characterization (dogs)
ROlHL-11154-12 Blood group antigens and antibodies
(human)
P01HL11310-12 0095 Mechanisms of cardiovascular
disease - Blood and transfusion disorders (human, rats,
monkeys)
R01HL-n686-09 Dynamics of thrombus formation and
dissolution (human, chickens)
** R01HL1299409 The Rh complex of red cells (human)
R01HL13336-09 Biochemistry and physiology of human
platelets
** ROlHL-13585-05 Heterogeneity of NADH methemoglobin
reductase (human)
ROlHL-13629-08 Hemorrhagic diseases (human)
P60HL-1 51 58-07 0020 Comprehensive sickle cell center -
Immunochemical investigation of hemoglobin variants
(human)
ROlHL-15690-07 Hydrolytic enzymes of blood in health
and disease (human, animals)
** ROlHL-16626-05 Studies of antibodies to antihemophilic
factors (human, rabbits)
NO I HI M,b4bO'i
(human)
ROIHI 16/20 02
ROIHL 16/5/04
ROIHI 168/2 04
BLO
Paltiotiiolrjiy uf \hiun\ln9mUo\ii. dllo(d«fl
Pliteitt i|ir«|ali«n (human)
Autoimmune Ihrombocytopania (monkty)
Antihemophilii liilor (human)
P60H1 1/265 04 0003 Community blood r««ourca c«nt((
support Research Human factor IX Role in tntriniic
clotting (al^o baboons dogs)
P60HI 1/265 04 0006 Community blood resource canter
support Research Evaluation of platelet tiansfutioni
(human, dog)
ROIHI 1//52 03 Purified human clotting laclor IX
Immunologic studies (human)
ROIHL 18012 04 Cellular delects in nocturnal
hemoglobinuria (human)
ROIHI 18186 04 Cardiac allografts in autologous
radiation chimeras (rats, dogs)
ROIHI 1885903 Brochemlstry of human factor XI (human)
ROIHL 18935 03 '' '■nen. soluble fibrin
interaction (humoni
ROIHL 1910502 Detection and adherence of fibrin
monomer complexes (human)
** ROIHL 19646 03 An immunologic study of hemoglobin
variation in man
•• ROIHL 1976/ 01 Palhochemistry of fibrinogen (humans)
** ROIHL 20014 02 Radioimmunoassay of hyper and
hypocoagulable states (rabbits)
ROIHL 20314 02 Host defense against S pheumoniae in
sickle cell disease (human)
P60HL 20985 01 0007 Northern California sickle cell
center Immunohemalologic abnormalities in sickle cell
anemia (human)
R23HL 2120802 Structure function relationships of human
factor VIII
ROlHL-2137901 Structure of factor VIII Von Willebrand
protein (human)
ROlHL-2140302 Blood clotting kinetics studied by
radioimmunoassay (human)
** ROlHL-2143102 Factor II antigen and coagulant activity
(human, animals)
** ROlHL-2 1543-02 Structure-function relation of blood
clotting proteins (rabbits)
R23HL-21730-01 vWagll A new vWD deficient antigen
(human)
ROlHL-21975-01 Studies on normal and abnormal factor
IX (human, dogs, cows)
** ROlHL-22355-01 Purification, structure and function of
factor VIII (human)
ROlHL-22505-01 Molecular pathology of fibrinogen and
factor XIII (human, animals)
ROlHL-22671-01 Removal of senescent and stored human
red cells
R23HL-22799-01 Interaction of the complement and
coagulation systems (monkeys)
ROlHL-23654-01 Selected topics on blood transfusion
(rabbits, human)
BLOOD AND RE SYSTEM, LYMPH
** ROlHL-03180-21 Relation of lymphatics to
cardiopulmonary function (dogs)
ROlHL-10940-13 Lipid transport (rabbits, cattle, chickens)
P01HL11678-11 0070 Cardiovascular dynamics and their
control - Interaction of the four Starling forces (dogs)
" ROlHL-13341-06 Lymph -An indication of splanchnic tissue
respiration (dogs, human, rats)
P50HL-14164-07 0033 A/S SCOR-Comparative and
experimental atherosclerosis - Comparative studies of
lipoprotein distribution and metabolism (monkeys)
P50HL14164-07 0037 A/S SCOR-Comparative and
experimental atherosclerosis - Genetic control of plasma
cholesterol-Interaction of dietary fatty acid (monkey)
** ROlHL-17781-03 Hypertension, kidney disease and renal
lymph (dogs, rats)
BLOOD AND RE SYSTEM, LYMPH FLOW
ROlHL-04512-19 Ultrastructural studies of capillary
permeability (rats, mice)
POlHL-08899-14 0025 Tolerance to respiratory gases in
health and disease - Effects of oxygen on cardiopulmonary
gas transport functions (dogs)
" POlHL-11678 11 0035 Cardiovascular dynamics and their
control - Lymph flow rate and protein concentration (dogs)
POlHL-11678-11 0036 Cardiovascular dynamics and their
control - Pulmonary capillary dynamics and edema (dogs)
POlHL-11678-11 0039 Cardiovascular dynamics and their
control - Capillary and interstitial fluid dynamics of the
intestine (cats)
R01HL16916-04 0001 The role of albumins in lung water
accumulation - Capillary permeability (dogs, human)
** R01HL18010-04 Capillary transport ot large molecules
(dogs, sheep)
M P50HL-19153-02
pathogenesis
P50HL 19153-02 0001 SCOR-Pulmonary edemas-Eitology,
pathogenesis • Prostaglandins and the lung circulation
(sheep)
P50HL19153-02 0002 SCOR-Pulmonary edemas-Eitology,
pathogenesis - Lung fluid dynamics-Classical mediators
and their inhibitors (sheep)
P50HL19153-02 0003 SCOR-Pulmonary edemas-Eitology,
pathogenesis - Possible inhibitors of mediator release and
pulmonary vascular response (sheep)
(contd)
SCOR-Pulmonary edemas-Eitology,
*Ewludes routine melhodok>gy OR cavers only general proiects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number
BLO
48
BLO
" P50HL-19153-02 0004 SCOR-Pulmonaiy edemas-Eitology,
pathogenesis Physical mechanisms In lung transvascular
transport -Math models (sheep)
P50HL19153-02 0007 SCOR-Pulmonaty edemas-Eitology,
pathogenesis - Core-Experimental laboratories and support
facilities
** R01HL19370-03 Coronary capillary exchange-The effects
of ischemia (dogs, sheep)
POlHL-20994-02 0001 Dynamics of neutrophil elastase in
the lung • Dynamics of neutrophil elastase in normal
animals (dogs, rabbits)
ROlHL-21076-02 Lung fluid, protein exchange after
hemorrhagic shock (sheep)
ROlHL-21452-02 Pulmonary capillary filtration in
myocardial ishemia (dogs)
ROlHL-2149802 Pathophysiology of edema (rats, cats)
ROlHL-21948-01 Capillary, tissue volume and lymph flow
in lung edema (sheep, cattle)
ROlHL-22520-01 Pulmonary vascular response to group B
Streptococci (human, mammals)
** R01HL-22549-02 Transport across alveolar capillary
membrane (dogs)
POlHL-22602-01 0002 Pathophysiology of the
endothelium - Molecular charge and endothelial
permeability (rats, mice)
** ROlHL-22911-01 Mechanism of clearance of lung edema
fluid (dogs)
** R23HL-22933-01 Transvascular fluid and protein exchange
in the lung (sheep)
BIOOO AND RE SYSTEM, LYMPHATIC
CIRCULATION (GENERAL)
** ROlHL-03180-21 Relation of lymphatics to
cardiopulmonary function (dogs)
ROIHL 12493-10 Bioengineering analysis of microvascular
function (cats, rabbits)
R01HH3341-06 Lymph -An indication of splanchnic tissue
respiration (dogs, human, rats)
** ROlHL-1390108 Ontogeny, ultrastructure, function in
lymphatic system (birds, fish, mammals)
ROlHL-1615405 Membrane lung perfusion for acute
respiratory failure (sheep, baboons)
ROlHL-17596-03 Leukocyte-endothelial interactions (rats)
P50HL-1764604 0005 Study of ischemic heart disease -
Biochemical markers and mediators of myocardial ischemic
injury
P50HL-1915502 0004 Pathophysiology of pulmonary
edema - Physical and chemical effects of multiple
pulmonary emboli (sheep)
** P50HL19155-02 0005 Pathophysiology of pulmonary
edema - Protein exchange sites and lymph protein
concentration in lung (mice, sheep)
P50HL19185-02 0004 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Fluid and protein transport
in fetal and newborn lung (sheep, rabbits)
BLOOD AND RE SYSTEM, LYMPHATIC
CIRCULATION, THORACIC DUCT
R01HL13341-06 Lymph-An indication of splanchnic tissue
respiration (dogs, human, rats)
BLOOD AND RE SYSTEM, LYMPHATIC DUCT
DRAINAGE
POlHL-06285-18 0145 Cardiovascular-respiratory
physiology and biochemistry - Pulmonary, pleural and
systemic microcirculation (animals)
** POlHL-06312-17 0029 Surgical cardiology - Cardiac
lymphatics in the transplanted heart (dogs)
ROlHL-1317210 Post-trauma lung mechanics and fluid
exchange (human, dogs, monkeys)
ROlHL-23211-01 Active normoxic pulmonary vasodilatation
(rat. dog, sheep)
BLOOD AND RE SYSTEM, LYMPHATIC TISSUE
SEE ALSO BLOOD AND RE SYSTEM, SPLEEN
** POlHL-13 108-09 0016 Clinical heart transplantation ■
Total lymphoid irradiation for immune response (dogs)
" POlHL-16769-05 0010 Pathobiologic and host defense
reactions in the lung - Bronchus associated lymphoid
tissue and delayed hypersensitivity (rabbits)
ROlHL-19741-03 Murine CRD -A model of chronic
pulmonary inflammation (mice, rats)
ROlHL-19760-01 Cellular immune responses of the lung
(mice, guinea pigs)
ROlHL-22924-01 The airway mucosal barrier (guinea pigs)
BLOOD AND RE SYSTEM, LYMPHATIC TISSUE,
LYMPH NODES
** R01HL08696-15 0010 Orthotopic heart transplantation -
Transplantation immunology-Total lymphoid irradiation
(dogs, primates)
P01HL16769-05 0003 Pathobiologic and host defense
reactions in the lung • Pathobiologic mechanisms of
delayed sensitivity reactions in the lung (animals)
R01HL17596-03 Leukocyte-endothelial interactions (rats)
ROlHL-20954-02 Hyperlipoproteinemia (rats, human)
BLOOD AND RE SYSTEM, MACROPHAGES
SEE ALSO LIVER CELLS, KUPFFER CELLS
SEE ALSO RESPIRATORY SYSTEM, ALVEOLAR MACROPHAGES
P01HL-03174-23 0005 Mechanisms of acute vascular
reaction to injury - Renal small vessel didease -Cell and
matrix response (human, mice)
POlHL-063 14-17 0046
cardiovascular disease
(human, mice)
POlHL-063 14-17 0048
cardiovascular disease
(rats, mice)
POlHL-063 14-17 0052
cardiovascular disease
Immunologic mechanisms in
Mediators of immune injury
Immunologic mechanisms in
Pathogenesis of glomerulonephritis
Immunologic mechanisms in
Role of cyclic nucleotides in
neutrophil function (human)
POlHL-063 14-17 0064 Immunologic mechanisms in
cardiovascular disease - Diabetic vascular disease (human,
rats, mice)
** POlHL-06314-17 0066 Immunologic mechanisms in
cardiovascular disease - Sensitization, cell-mediated
cytotoxicity, role of lymphocytes (human, mice)
POlHL-06314-17 0067 Immunologic mechanisms In
cardiovascular disease - Mitogenic and antigenic activation
of lymphocyte sub-populations
ROlHL-07652-14 Destruction of red blood cells in
hemolytic anemias (human, guinea pigs)
POlHL-08682-15 0019 Regulation of the cardiovascular
system - Hepatic immunophysiology and host-defense in
shock (rat, dog, human)
POlHL-08682-15 0020 Regulation of the cardiovascular
system - Hepatic metabolic basis of shock (rat)
ROlHL-12839-09 Flow, transport and membrane
phenomena in blood (human)
P50HL-14147-08 0006 Specialized center of research in
thrombosis - Clearance mechanisms of coagulation
moieties (human, rabbits, rodents)
P50HL-141 53-07 0004 Johns Hopkins Lung Center-
Chronic diseases of airways - Macrophage enzymes in lung
injury, inflammation and repair (rabbit)
P50HL-15061-07 0009 Response of lung to injury -
Alveolar macrophages (human, rabbits)
P60HL-15999-05 0008 Miami comprehensive sickle cell
center - Cyanate effect on host defense -Cellular and
humoral (human, guinea pig. rabbits)
POlHL-174 17-05 0003 Experimental lung transplantation
- Methods for detecting lung allograft rejection (dogs)
P01HL18827-02 0006 Platelet vessel wall interactions in
thrombogenesis - Platelet immune injury in man
ROIHL- 190 10-03 Metabolism and cell biology of lung
surfactant system (rabbits, sheep)
P50HL-191 71-02 0007 Pulmonary SCOR-Lung injury by
childhood infections - Immunologic studies in models of
lower respiratory tract infection (rodents)
ROlHL-194 19-03 Cellular interactions with foreign
materials (mammals)
ROlHL-19628-03 Mechanisms of pulmonary alveolar
proteinoses (human, rats)
** R01HL19732-03 Lymphokines in pulmonary
granulomatous inflammation (mice)
ROlHL-19774-03 Pathogenesis of chronic lung disease
(rats, mice, bacteria)
ROlHL-19779-03 Biochemical basis of oxygen damage to
lung cells (guinea pigs, rats)
ROlHL-20104-03 Pulmonary granulomatous inflammations
(mice)
ROlHL-21047-01 Studies of coxsackievirus-induced
myocarditis in mice
R23HL-21 134-02 Immune function and fibrogenesis in
silicosis (guinea pigs)
ROlHL-21156-02 Antitrypsin and other causes of chronic
lung disease
** R23HL-212 12-02 Alveolar macrophage function in
Pseudomonas infection (dgs)
R23HL-21805-01 Tissue cell interactions with vascular
prostheses (human, rats, mice)
ROlHL-22456-01 Lipoproteins in bioregulation of the
immune response (mice, human)
" ROlHL-22474-01 Cholesterol metabolism and
atherosclerosis (rats, human, rabbits)
ROlHL-2255501 Structure and function of platelet
activating factor (rabbits, human)
** ROlHL-22671-01 Removal of senescent and stored human
red cells
ROlHL-22739-01
atherosclerosis
ROlHL-23654-01
(rabbits, human)
BLOOD AND RE SYSTEM, MAST CELLS
ROlHL-02953-17 Autonomic and cardiovascular
pharmacology (rats, rabbits, dogs, guinea pigs)
** POlHL-031 74-23 0009 Mechanisms of acute vascular
reaction to injury - Mast cell lipid interaction (human, rats)
POlHL-0789615 0043 Environmental biomedical research
program - Effect of hyperbaric oxygen on the lung (human,
rabbits)
P50HL-141 53-07 0015 Johns Hopkins Lung Center-
Chronic diseases of airways ■ Kinins and human lung
** POlHL-14985-07 0010 Adaptation to hypoxia - Pulmonary
mast cell (animals)
** POlHL-164 11-04 0001 Blood systems in coagulation and
vessel disease - Molecular studies of the role of
complement in blood coagulation (human, rabbits)
POIHL- 178 13-04 0001 Lung disease and the oxygenation
of blood and tissue - Diffuse interstitial lung disease-
Pathophysiology (human, dogs)
** ROlHL-1906203 Pharmacologic control of mast cell
phosphodiesterase (human, rats)
Evolution and progression of pediatric
Selected topics on blood transfusion
** P50HL-19156-02 0004 Pulmonary SCOR-Chronic diseases
of airways - Interactions between mast cells, mediators
and nerves in canine asthma
ROlHL-19777-03 Regulation of hypersensitivity in the lung
(rats, guinea pigs, rabbits, human)
** R23HL-21089-02 Localization of mediators in dispersed
lung cells (guinea pigs, human)
R01HL-215e5-02 Pathogenesis of inflammatory lung injury
(rats, rabbits)
R23HL-22011-01 Adrenergic receptor cyclase system in
sensitized lung (rats, guinea pigs)
ROlHL-22402-01 Heparin-biophysical, chemical and
biological aspects (mice, human)
ROlHL-23209-01 Autonomic receptors of the pulmonary
vasculature (mammals)
** ROlHL-23593-01 Mast cell granules-Structure and
secretion (rats)
BLOOD AND RE SYSTEM, MEGAKARYOCYTES
ROlHL-13336-09 Biochemistry and physiology of human
platelets
R01HL14637-05 Thrombopoietin-lmmunoassay and
characterization (mice)
** POlHL-18208-04 0003 Center for the study of blood cell
rheology - Bone marrow microcirculation (rats, mice)
ROlHL-18714-04 Cardiovascular matrix-Morphogenesis
and maturation (human, chick embryo, mammal)
P50HL 18828-03 0001 Specialized center of research in
thrombosis Membrane biology and hemostasis (human)
P50HL-18828-03 0005 Specialized center of research in
thrombosis - Platelet inflammatory factors in thrombosis
(human, guinea pig)
** P50HL-18828-03 0009 Specialized center of research in
thrombosis - Platelet formation and megakaryocyte cell
biology (guinea pig. human)
ROlHL-19270-03 Effects of erythropoiesis on platelets and
hemostasis (rats)
** R01HL-2082e-02 Megakaryocyte proliferation and its
control (mice)
** POlHL-22633-01 0003 Cellular and molecular biology of
lipoprotein metabolism Sterol metabolism in platelets and
megakaryocytes (human, rabbits, guinea pigs)
BLOOD AND RE SYSTEM, RE STIMULATING
FACTORS
SEE ALSO BLOOD AND RE SYSTEM, HEMATOPOIETIC FACTORS
" ROlHL-1800203 Circulatory shock, trauma and RE-system
function (rats)
BLOOD AND RE SYSTEM, RETICULOENDOTHELIAL
SYSTEM (GENERAL)
POlHL-08682-15 0019 Regulation of the cardiovascular
system - Hepatic immunophysiology and host-defense in
shock (rat, dog, human)
POlHL-08682-15 0020 Regulation of the cardiovascular
system Hepatic metabolic basis of shock (rat)
** POlHL-08682-15 0021 Regulation of the cardiovascular
system Hypoglycemia in pathogenesis of shock (dog)
R01HL18284-04 Aging erythrocytes-Bio-recognitlon and
elimination (monkeys)
** ROlHL-18731-02 RES stimulating materials in
experimental shock (dogs)
R23HL-21271-02 Extracorporeal circulation and protein
denaturation (human)
ROlHL-22470-01 Liposome myocardial uptake in infarct
and ischemia (dogs, rats, mice)
BLOOD AND RE SYSTEM, SPLEEN
SEE ALSO BLOOD AND RE DISORDERS, SPLENIC DISORDERS
ROlHL-07723-15 Reflex control of vascular capacitance in
shock
POIHL- 16 748-05 0006 Cellular and immunological basis
of pulmonary diseases - Sarcoidosis -Studies with bronchial
lavage (human)
ROlHL-18096-04 Vasoactive agents in splanchnic viscera
(primates, dogs)
POlHL-18208-04 0003 Center for the study of blood cell
rheology - Bone marrow microcirculation (rats, mice)
** POlHL-18208-04 0004 Center for the study of blood cell
rheology - Splenic microcirculation (rats, mice)
ROlHL-18995-04 Cardiovascular determinants of
catecholamine release (dogs)
** ROIHL-20086-02 Circulatory control of splenic function
(rats)
ROlHL-20787-02 Thromboxanes and prostaglandins-
Biochemical pharmacology (rabbits, human)
ROlHL-21159-02 Pathophysiological effects of hypoxia
(rats)
ROlHL-22367-01 Estrogen receptors in very low density
lipoproteins (chicken livers)
BLOOD AND RE SYSTEM, SPLEEN TISSUE (CELLS)
TRANSPLANTATION
** R01HL-16119-05 Spleen and marrow allografts in
hereditary anemia (mice)
ROlHL-20086-02 Circulatory control of splenic function
(rats)
ROlHL-20170-02 Pulmonary infection in splenectomized
animals (mice)
BLOOD AND RE SYSTEM, SPLENECTOMY
ROlHL-13341-06 Lymph-An indication of splanchnic tissue
respiration (dogs, human, rats)
ROlHL-16757-04 Autoimmune' thrombocytopenia (monkey)
(contd)
'Excludes routine methodokigy OR covers only general projects which preclude indexing at the specific level.
"Oriented sicnificantty to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
BLO
49
BIO
Biochemistry and physiology of human
RUIHl 1899/02 Ischemic thetipy In uptrlmantil
hypecipUnlsni (ids. dogs)
ROIHl 19760 01 Cellulai imnuing lesponsts ol tht luni
(mica, guinaa pigs)
ROIHL 20086 02 Clrculaloty contiol ol splanic lunclion
(rats)
" ROIHL 2U WO 02 PulmonaiY intection in splenactomijod
animals (mica)
P60HI 23282 01 0002 Compiehensive huspital/community
sickle cell cental Clinical ev.iluatian ol alleinate
pathaway ol compliment activation
BLOOD AND RE SYSTEM, THYMECTOMY
KOIHL 16246 06 Immunologic studios in
postpericaidiotomy syndrome (human)
ROIHL 22301 01 Immunogenetics ol chronic pulmonaiy
intlammation (mice)
BLOOD AND RE SYSTEM, THYMOSIN
P60HL'1600806 0019 Wayne State Univeisily
comprehensive sickle cell centei Cell mediated immunity
in sickle cell anemia (human)
ROIHL 19/74 03 Pathogenesis of chronic lung disease
(rats. mice, bacteria)
BLOOD AND RE SYSTEM EXAMINATIONS
StE BLOOD AND RE DISORDERS DIAGNOSIS (INCL EXAMS)*
BLOOD AND RE SYSTEM PHARMACOLOGY
SEE ALSO BLOOO AND RE DISORDERS CHEMOTHERAPY
NOIHB'22922 08 Develop etfective therapy lor sickle cell
disease (human, dogs)
POIHL 04664 18 0008 Cardiovascular and lung dynamics
■ Micrographic video imaging technique
R01HL09163 13 Control mechanisms in hemostasis
(human)
** ROlHL-0973913 Biophysical studies of proteins (human)
ROIHL 10383 12 Physical chemical studies of hemoglobins
and erythrocyte (human)
ROIHL 1225615 Polymerization of sickle-cell hemoglobin
(human)
R01HL1333609
platelets
R01HL-13466-08 Pulmonary platelets in shock, trauma
and embolization (dogs. pigs, rats)
** P50HL1421708 0057 Specialized center of research in
thrombosis - Pharmacology-Platelet biochemistry (human,
animal)
** P50HL-14217 08 0061 Specialized center of research in
thrombosis - Pharmacology-Comparison of platelets and
vascular smooth muscle (animal)
ROlHL-14739-06 The role of leukocytes in thrombotic
disease (human, dogs)
P60HL1515707 0009 Comprehensive center for sickle
cell disease - Red cell membrane alterations during
sickling (human)
P60HL-15157-07 0011 Comprehensive center for sickle
cell disease - Development of specific anti-sickling
compound (human)
P60HL-15158-07 0011 Comprehensive sickle cell center -
Clinical services-Adult patients
P60HL15162-07 0019 Comprehensive sickle cell center -
RBC-Blood rheology in sickle cell anemia and related
disorders (human, animal)
P60HL-1516807 0009 Comprehensive sickle cell disease
center - Spin-label study of sickling (human)
** ROlHL-15293-07 Sickle cell hemoglobin-Interactions and
aggregation (human)
ROlHL-15668-06 Extracorporeal respiratory gas exchange-
A new approach (dogs)
*• P60HL1 5999-05 0021 Miami comprehensive sickle cell
center - Diphosphonates-Erythrocyte calcium loading,
maturation (human, chick embryo)
POlHL-16387-04 0005 The blood vessel and
thrombogenesis - Fluid engineering considerations in
thrombogenesis
ROlHL-16582-05
R01HL-I6647-05
(human)
POlHL-16833-04 0009
hemoglobinopathies
(human)
POlHL-16833-04 0017
hemoglobinopathies
effect (human)
P60HL-1 7265-04 0003 Community blood resource center
support - Research-Human factor IX-Role in intrinsic
clotting (also baboons, dogs)
ROlHL-1 7479-04 Blood storage -The production of
cardiotoxic material (dogs, human, swine)
R01HL-17571-03 Study of membrane permeability by NMR
relaxation (human)
ROlHL-17596-03 Leukocyte-endothelial interactions (rats)
ROlHL-17747-04 Endothelial injury and regeneration (rats)
POlHL-17812-04 0004 Thrombosis and plasma proteins -
Serum-platelet interaction (human)
POIHL-17812-04 0005 Thrombosis and plasma proteins -
In vitro systems of normal platelets, white cells, sera
(human)
ROlHL-1793003 Platelet membrane function-Assessment
and application (animals)
ROlHL-18002-03 Circulatory shock, trauma and RE-system
function (rats)
Artificial lungs (dogs)
Studies on the control of sickle cell crisis
Hemoglobin and red cell system in
Rheological studies of sickled cells
Hemoglobin and red cell system in
Sulfhydryl group blockade antisickling
POIHI 18208 04 UDOS Cenlei tor the kludy ol bliiud mil
rheology RH(' deloiiiiiibility and capillary How
intorielnlluns (human, micel
POIMI l8S/6 0:i onni llirumbosis research program
pinicrt Phitrli't d.image liom physical forces and
ditiliiial surfiiies (humnn)
POIHL 185/6 0:1 000/ Ihrombosis research program
project Relationships between coagulability and
thrombosis (human, animals)
POIHL 185/6 03 0012 Thrombosis research program
protect Synthetic anticoagulant and thrombolytic agents
(dogs)
ROIHL 1864403 Prosthesis lor aortocoronary bypass
(dogs, baboons)
ROIHL 18660 03 Neurotransmitter receptors in human
erythrocytes
POIHL 18827 02 0006 Platelet vessel wall interactions in
thrombogenesis Platelet immune injury in man
P50HL 18828 03 0004 Specialized centei ol research in
thrombosis Membrane changes in platelet physiology Role
of complement (mice, human)
P50HL 18828 03 0005 Specialized center of research in
Ihrombosis Platelet inflammatory factors in thrombosis
(human, guinea pig)
P50HL 18828 03 0008 Specialized center of research in
thrombosis Biochemistry, physiology Platelets and
subcellular platelet particles (human)
P50HL 18828 03 0009 Specialized center of research in
thrombosis Platelet lormation and megakaryocyte cell
biology (guinea pig, human)
ROIHL 1909503 Laser spectroscopy of lipoproteins
(human)
** R01HL1953201
R01HL-20319 02
fibrin (human)
** P60HL-20985 01 0006 Northern California sickle cell
center - Antisickling properties of imidoesters (human, rats)
POlHL-21016-02 0010 Sickle cell anemia and other
hemoglobinopathies Alkylureas as potential antisickling
agents
R23HL-2 11 29-02 The antisickling effects of imidoesters
R23HL-214 13-02 Structure and function of platelet
calcium-binding protein (human)
** ROlHL-22035 01 Molecular modification of heparin by
chemical means (sheep)
POlHL-22163-01 0003 Surface thrombogenesis -
Mechanisms and prevention - In vivo mechanisms of
biomaterial thrombogenesis and its prevention (baboons)
ROlHL-221 94-02 Allosteric function of platelet contractile
proteins (human)
ROlHL-22607-01 Role of apolipoprolein E in lipoprotein
metabolism (human)
BLOOD BACTERICIDAL ACTIVITY (GENERAL)
SEE IMMUNITY, BACTERICIDAL DEFENSES (GENERAL)
BLOOD BANKS
SEE BLOOD PRESERVATION, BLOOD BANKS, CENTERS-
RESOURCES-REGISTRIES
BLOOD-BRAIN BARRIER
SEE CEREBROVASCUUR SYSTEM,
Oxygen toxicity in the red cell (human)
Assembly, structure and interactions of
BLOOD-BRAIN BARRIER
BLOOD CELL COUNT
SEE BLOOO (HEMATOLOGIC) TESTS, BLOOD CELL COUNT-
BLOOD CELL DEPLETION THERAPY, LYMPHOCYTE
DEPLETION
SEE ALSO BLOOD AND RE SYSTEM, LYMPHATIC DUCT
DRAINAGE
ROlHL-14799-07 Cardiac heterotransplantation-
Immunologic modification (mice, rat)
BLOOD CELL DEPLETION THERAPY, T
LYMPHOCYTE DEPLETION
ROlHL-08696-15 0010 Orthotopic heart transplantation -
Transplantation immunology-Total lymphoid irradiation
(dogs, primates)
BLOOD CELL FORMATION
SEE BLOOD AND RE SYSTEM. HEMATOPOIESIS
BLOOD CELLS
** ROlHL-12944-09 Enzymatic and biochemical studies on
blood cells (human)
** POlHL-16851-04 0009 Human red cell membrane in
health and disease - Blood cell properties in circulatory
regulation (dogs, rabbits)
** POlHL-16851-04 0012 Human red cell membrane in
health and disease - Computer unit-Core facility
BLOOD CELLS, ERYTHROBLASTS AND ERYTHROID
STEM CELLS
SEE ALSO BLOOD AND RE DISORDERS. ANEMIA
SIDEROBLASTIC
ROlHL-046 12-20 Feedback between red cell production
and oxygen transport (rabbits, rats)
P60HL-I5999-05 0019 Miami comprehensive sickle cell
center - Fetal-adult hemoglobin switch (mouse, monkey)
ROlHL-20300-02 Histone H5 and avian erythropoiesis
(chickens, rabbits)
*♦ ROlHL-20899-02 Cellular mechanisms of hemoglobin F
regulation (human)
ROlHL-20905-02 Synthesis of fetal hemoglobin in erythroid
cells (sheep, human)
*Excludet routine methodology OR covers only general projects which preclude indexing
••Onented significantly to above subject.
BLOOD CELLS, ERYTHROCYTES
Ml AI'.U IIIIKiD AND hi iJl'.UNDI N'.. ANI MIA
SI I Al',>0 BIOUD AND Ri DI'.UROI K;.. UONi MARROW
POIYIYIHIMIA
SEE ALSO fiLOUb AND Rl '.y:,I(M. HrMAIOPOIF^S.
fRYIIlROCOIIM',
Stf AISOBIOOD IRIAtMFNI I'lA'.MAI'IIIRISIS
SEE Also HIMUPROIIIN',. Ml M(JOI UIIINOPATHIES
SEI AISOMfMHRANf IRYIIIROCYIE UHOSI AND
MIMIIKANf
SE! ALSO PROILINS. MEMBRANE PROTEINS. SPECTRIN
" NOIHB 62962 02 Red cell diilributioni in cyanilf-traaled
blood (human, sheep)
POIHI 03174 23 0000 Mechanisms of acute vatcular
reaction to injury Atherosclerotic plaque sludiei using
mosaic analysis (human)
POIHL 03174 23 0010 Mechanisms of acute vascular
leaction to injury Search lot mutagens in the human
blood (bacteria, animals)
POIHI 06835 1/ 0019 Cardiovascular disease Fatty
acid distribution (rats)
•• RaiHL06950 17 Red cell metabolism (human,
vertebrates)
" R01HL07449 1/ Formation and survival of red blood cells
(human)
POIHL 09011 15 0001 A research and resource program
in blood Genetic markers of human blood and gene
mapping (human)
" ROIHL 09906 13 0019 Membrane transport processes in
red blood cells Hemoglobin change and membrane
potentials in red blood cells at varying volumes
" ROIHL 09906 13 0020 Membrane transport processes in
red blood cells - Calibration of a fluorescent probe for
erythrocytes
** ROlHL-09906 13 0021 Membrane transport processes in
red blood cells Membrane potentials in human red blood
cells due to proton gradients
" ROIHL 09906-13 0022 Membrane transport processes in
red blood cells Anion transport in dog and cat red cells
** ROIHL 09906 13 0023 Membrane transport processes in
red blood cells Cation and anion movements in two sub
groups of dog erythrocytes
** ROIHL 09906 13 0024 Membrane transport processes in
red blood cells - Inhibition of sulfate transport in human
RBCs by isothiocyanic acid esters
** ROlHL-09906 13 0025 Membrane transport processes in
red blood cells - Mechanism of propranolol induced Ca-
dependent K efflux from human RBCs
** ROIHL 10036-13 Biology of red cell antigen-antibody
reaction (human)
** ROIHL 10383-12 Physical-chemical studies of hemoglobins
and erythrocyte (human)
ROlHL-11152-12 Vascular physiology (human, cats, dogs)
R01HL-U901-12 0017 Effects of metabolic surgery on
the hyperlipidemias - Membrane permeability, blood
viscosity, oxygen uptake-Rheology studies (rabbits)
ROlHL-12684-09 Angiotensin I and converting enzyme in
hypertension (human, primates, dogs)
** ROlHL-12972-09 Glutathione deficiency in red cells
(sheep, dogs)
** POlHL-13108-09 0012 Clinical heart transplantation •
Human T cell sheep erythrocyte receptors
** ROlHL-13237-09 Erythrocytes during early development
(human, animals)
ROlHL-13585-05 Heterogeneity of NADH methemoglobin
reductase (human)
POlHL-13737-07 0026 Assisted circulation • Hemostatic
mechanism (human, dogs)
ROlHL-14127-16 Methemoglobinemia and antihypertensive
drugs (cats, mice, rats)
P50HL-14217-08 0050 Specialized center of research in
thrombosis - Electron microscopy section (dogs)
P50HL-14230-07 0093 A/S SCOR-Lipids, atherosclerosis
and thrombosis Clinical studies involving cellular lipid
content (human)
POlHL-14414-07 0014 Environmental influences on
cardiorespiratory and cellular functions - Temperature and
acid-base status in tissues, cells, and subcellular system
POlHL-14985-07 0011 Adaptation to hypoxia -
Prostaglandins in the control of the pulmonary circulation
(animals)
POlHL-14985-07 0012 Adaptation to hypoxia - Direct
effect of hypoxia on pulmonary vascular smooth muscle
(rats, dogs)
P50HL-15061-07 0013 Response of lung to injury -
Exchange transfusion in infants with respiratory distress
syndrome (human, sheep)
ROIHL 15124-05 Genesis of hypertension in renal disease
(human, dogs)
P60HL-15157-07 0011 Comprehensive center for sickle
cell disease - Development of specific antisickling
compound (human)
P60HL-15157-O7 0012 Comprehensive center for sickle
cell disease - Sickling and intracellular pH (human)
** P60HL-15160-07 0011 Center for sickle cell disease -
Study of human sickle cells in an animal model (rats)
** P60HL-15162-07 0017 Comprehensive sickle cell center -
Hemoglobin, erythrocytes and sickle cell anemia (human,
rabbit)
** P60HL-15162-07 0019 Comprehensive sickle cell center -
RBC-Blood rheology in sickle cell anemia and related
disorders (human, animal)
(contd)
at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
so
BLO
Studies on the control of sicKle cell crisis
Left ventricular function in exercise
Hemoglobin and red cell system In
Rheological studies of sickled cells
P0lHL-lSt9407 0006 Pathophysiology of
cardiopulmonary dysfunction - Kinetics of gas exchange-
Velocity of Bohr effect in erythrocytes (human)
P01HI.1519407 0009 Pathophysiology of
cardiopulmonary dysfunction ■ Kinetics of gas exchange-
Diffusion and erythrocytes reaction rates (human, dogs)
POlHL-15194-07 0022 Pathophysiology of
cardiopulmonary dysfunction - Kinetics of gas exchange -
Pulmonary carbon dioxide exchange (dogs)
ROlHL-15226-06 Interaction of blood cells with fibrinogen
and fibrin (human, animals)
ROlHL'15722-06 Hemorrheology studies related to in vivo
blood flow (human)
P60HL-1 5996-06 0010 Cincinnati comprehensive sickle
cell center - Whole blood viscosity in sickle cell anemia
(human)
P60HL-15999-05 0014 Miami comprehensive sickle cell
center - Biochemical and morphological parameters of
sickle cells (human)
P60HL-1 5999-05 0021 Miami comprehensive sickle cell
center - Diphosphonates-Eiythrocyte calcium loading,
maturation (human, chick embryo)
P60HL-1600806 0014 Wayne State University
comprehensive sickle cell center - Zinc and red blood cell
metabolism in sickle cell anemia (rats, human)
P60HL-1600g-06 0016 Wayne State University
comprehensive sickle cell center - Red blood cell glycolysis
In sickle cell patients
P60HL-16008-06 0017 Wayne State University
comprehensive sickle cell center - Oxygen transport kinetics
of pre- and post-sickling cells (human)
ROlHL-16093-05 Functional properties of hemoglobin and
erythrocytes
ROlHL-16421-08 Determinants of RBC deformability and
capillary flow (human, mice)
R01HL-16580-04 Mathematical models for studying sickle-
cell disease
ROlHL-16647-05
(human)
ROlHL-16656-06
(dogs)
POlHL-16833-04 0009
hemoglobinopathies -
(human)
POlHL-16833-04 0016 Hemoglobin and red cell system in
hemoglobinopathies - Calcium-indiced membrane damage
In Hb SS disease (human, animals)
POlHL-16851-04 Human red cell membrane in health and
disease
P01HI-168S1-04 0009 Human red cell membrane in
health and disease - Blood cell properties in circulatory
regulation (dogs, rabbits)
POlHL-16851-04 0011 Human red cell membrane in
health and disease - Ultrastructure laboratory-Core facility
POlHL-16910-05 0001 Regulation of the peripheral
circulation - Quantitative studies of microcirculatory control
(bats)
ROlHL-16931-04 Red cell storage and transfusion
(human, animals)
ROlHL-17571-03 Study of membrane permeability by NMR
relaxation (human)
ROlHL-17808-03 Effect of altered oxygen affinity on
oxygen transport (human, rats)
ROlHL-1 7878-04 Structural studies of the human
erythrocyte membrane
ROlHL-17881-15 Biosynthesis and degradation of blood
group substances (human, animals)
ROlHL-17963-04 Human erythrocyte carbonic anhydrase
ROlHL-17967-04 Limiting factors in oxygen uptake in the
lung
' ROlHL-18082-03 Erythrocyte phosphates and vertebrate
gas transport (amphibians, reptiles)
POlHL-18208-04 Center for the study of blood cell
rheology
POlHL-18208-04 0001 Center for the study of blood cell
rheology - Physiological basis of reversible erythrocyte
shape change (human, firefly)
' POlHL-18208-04 0002 Center for the study of blood cell
rheology - Holography of RBC shape (human)
POIHL-18208-04 0004 Center for the study of blood cell
rheology - Splenic microcirculation (rats, mice)
' P01HL-lg208-04 0005 Center for the study of blood cell
rheology - RBC deformability and capillary flow
interrelations (human, mice)
POlHL-18208-04 0006 Center for the study of blood cell
rheology - Analysis of flow in arterioles and capillaries
(human)
ROIHL- 182 56-01 Optical properties of platelets and
erythrocytes (rabbits, dogs, human)
ROlHL-18284-04 Aging erythrocytes-Blo-recognition and
elimination (monkeys)
ROIHL-18328-03 Hemoglobin function and tissue
oxygenation (human, dogs)
' R01HL-18S51-03 Spectrin, actin, lipid and red cell
membrane structure
' ROlHL-18660-03 Neurotransmitter receptors in human
Cfythrocytes
R01HL-1872S-03
process (human)
ROlHL-18818-04
Light-scattering studies of the sickling
Stereochemical mechanism of sickling of
hemoglobin S (human)
ROIHL- 194 19-03 Cellular interactions with foreign
materials (mammals)
** ROlHL-19532-01 Oxygen toxicity in the red cell (human)
POlHL-19737-02 0008 Cellular and molecular aspects of
respiratory physiology - Kinetics of movement of acid
metabolites from cell to capillary blood (dogs)
ROlHL-19824-02 Mass transfer in the microcirculation
R01HL-1994e-03 Reduction of Iron overload in
thalassemia (children, rabbits, dogs, monkeys)
ROlHL-20074-02 Structure and function of amidinated
human hemoglobin
** ROlHL-20 177-02 Effects of erythrocyte deformability on
tissue perfusion (rats)
ROlHL-20520-03 Protein modification-The key to diabetic
sequelae (human, animal)
** ROlHL-207 11-01 Structure-function relationships in red
cell NA-K pumps (goats)
** ROlHL-20882-02 Interactions of plasma lipoproteins with
erythrocytes (Rhesus, human)
** ROlHL-20902-02 Studies on marginal band system of
erythrocytes (amphibians, reptiles, fish)
ROlHL-20925-01 The acetylation of fetal hemoglobin
(human)
** ROlHL-20943-02 Comparision of microsphere and RBC
behavior in vivo
** P60HL-20985-01 0003 Northern California sickle cell
center - Kinetics of sickling and clinical manifestations in
sickling disorders (human)
** P60HL-20985-01 0004 Northern California sickle cell
center - Characterization of irreversibly sickled cells
(human)
** P60HL-20985-01 0006 Northern California sickle cell
center - Antisickling properties of imidoesters (human, rats)
POlHL-21016-02 0001 Sickle cell anemia and other
hemoglobinopathies - Supramolecular models of Hb S-
Mutational and EM approach
** POlHL-21016-02 0006 Sickle cell anemia and other
hemoglobinopathies - Analysis of the oxygen dissociation
curve of Hb S-containing red cells
R23HL-2 11 29-02 The antisickling effects of imidoesters
ROlHL-21 179-01 Volume regulation -Role of the membrane
potential (amphiuma)
** R23HL-2 13 28-02 The I blood group antigen of human
erythrocyte membrane
** ROlHL-21845-01 Human red cell membrane-Structure and
function
ROlHL-21995-01 Protein phosphorylation and adrenergic
effects
** ROlHL-22123-02 The role of the red cell in diabetic
atherosclerosis (human)
POlHL-22 163-01 0002 Surface thrombogenesis-
Mechanisms and prevention - Laser-scattering detection of
microemboli in blood flow (baboons)
ROlHL-22233-01 Characterization of bio-materials by
elastic property
ROlHL-22555-01 Structure and function of platelet
activating factor (rabbits, human)
** ROlHL-22671-01 Removal of senescent and stored human
red cells
** ROlHL-23200-01 Isolation of CA binding proteins from
erythrocytes (human)
ROlHL-23900-01 Mechanical measurement of cell
membrane viscosity (human)
ROlHL-23983-01 Quantitative radiocardiography (human,
dogs)
BLOOD CELLS, ERYTHROCYTES, HEMOLYSIS
SEE ALSO BLOOD AND RE DISORDERS, ANEMIA HEMOLYTIC
SEE ALSO BLOOD (HEMATOLOGIC) TESTS, OSMOTIC
FRAGILITY*
SEE ALSO BLOOD TOXICOLOGY, HEMOLYSINS
** R01HL-07652-14 Destruction of red blood cells in
hemolytic anemias (human, guinea pigs)
ROlHL-12839-09 Flow, transport and membrane
phenomena in blood (human)
POlHL-13738-08 0002 Cardiac assist devices and
artificial hearts - Total replacement with artificial heart
(calves, sheep, ponies)
POlHL-13738-08 0003 Cardiac assist devices and
artificial hearts - Pathophysiological effects of the artificial
heart (calves)
POlHL-13738-08 0004 Cardiac assist devices and
artificial hearts - Hematological evaluation of prosthetic
materials (calves)
POlHL-13738-08 0005 Cardiac assist devices and
artificial hearts - Development of new materials for
artificial heart and assist devices (sheep, dog)
ROlHL-13803-07 Advanced cardiac valvular and vascular
prosthesis (dogs, baboons)
P50HL-142 17-08 0051 Specialized center of research in
thrombosis - Microcirculation section (bat, hamster)
ROlHL-15793-06 Molecular aspects of erythrocyte
membrane resealing (human)
P60HL-15999-05 0014 Miami comprehensive sickle cell
center - Biochemical and morphological parameters of
sickle cells (human)
P60HL-16005-05 0022 Comprehensive sickle cell center -
Regulation of erythropoiesis in patients with sickle cell
anemia
** R01HL-ie421-08 Determinants of RBC deformability and
capillary flow (human, mice)
ROlHL-16711-05 RBC and endothelial membrane material
characteristics (human)
Hemoglobin and red cell system in
Erythrocyte membrane damage in Hb
POlHL-16833-04 0014
hemoglobinopathies
SS disease (human)
P01HL-ie851-04 0003 Human red cell membrane in
health and disease - Modeling membrane mechanics and
blood rheology
ROlHL-16938-05 Effect of physical forces on blood (dogs,
human)
P60HL- 17269-04 0032 National heart and blood vessel
research and demonstration center - Clinical circulatory
assist device fabrication
POlHL-17731-04 0010 Physiological basis of pulmonary
disease - Gas exchange kinetics (dogs)
** ROlHL-18012-04 Cellular defects in nocturnal
hemoglobinuria (human)
" ROlHL-18163-04 Red cell membrane effects due to
oxidizing agents
** POlHL-18208-04 0004 Center for the study of blood cell
rheology - Splenic microcirculation (rats, mice)
P50HL-18828-03 0004 Specialized center of research in
thrombosis - Membrane changes in platelet physiology-Role
of complement (mice, human)
** ROlHL-19163-02 Piscine erythrocytic necrosis in the
Atlantic cod
** ROlHL-19164-03 Piscine erythrocytic necrosis in the
Atlantic cod
** P60HL-20985-01 0007 Northern California sickle cell
center - Immunohematologic abnormalities in sickle cell
anemia (human)
ROlHL-23654-01 Selected topics on blood transfusion
(rabbits, human)
BLOOD CELLS, ERYTHROCYTES, RETICULOCYTES
ROlHL-06950-17 Red cell metabolism (human,
vertebrates)
P60HL-16008-06 0018 Wayne State University
comprehensive sickle cell center - Hemoglobin S and RBC
membranes-Pathogenesis of irreversibly sickled cells
POlHL-18208-04 0003 Center for the study of blood cell
rheology - Bone marrow microcirculation (rats, mice)
ROlHL-19324-02 Mechanisms of the inhibition of sickling
by DBA (human)
ROlHL-20859-02 Beta adrenergic catecholamine receptor
POlHL-2 10 16-02 0005 Sickle cell anemia and other
hemoglobinopathies - Ligand kinetics in normal and Hb S
containing erythrocytes (human)
POlHL-21016-02 0011 Sickle cell anemia and other
hemoglobinopathies - Metabolic effects of antisickling
agents (hamsters)
ROlHL-23736-04 Sickle cell anemia and hemoglobin
synthesis (monkeys)
BLOOD CELLS, HEMATOPOIETIC STEM CELLS
(GENERAL)
SEE ALSO BLOOD CELLS, ERYTHROBUSTS AND ERYTHROID
STEM CELLS
** ROlHL-15685-05 Hemopoietic regulators produced in cell
culture (human, animals)
POIHL- 174 17-05 0004 Experimental lung transplantation
- Methods for suppressing lung allograft rejection (dogs,
mice)
ROlHL-18186-04 Cardiac allografts in autologous
radiation chimeras (rats, dogs)
ROlHL-19333-03
ROlHL-20826-02
control (mice)
ROlHL-20912-02
thassemic mice
ROlHL-22555-01
Hematopoietic chimerism (mice, monkey)
Megakaryocyte proliferation and its
Control on non-alpha chain synthesis in
Structure and function of platelet
activating factor (rabbits, human)
BLOOD CELLS, LEUKOCYTES
SEE ALSO BLOOD CELLS, LYMPHOCYTES
SEE ALSO BLOOD CELLS, MONOCYTES
SEE ALSO BLOOD TREATMENT, LEUKAPHERESIS
SEE ALSO HYPERSENSITIVITY, TRANSFER FACTOR
(HYPERSENSITIVITY)
SEE ALSO IMMUNOLOGY, ANTIBODIES, HEMAGGLUTININS,
LEUKO-AGGLUTININS
POlHL-06350-17 0019 Hemostasis research program
project - Microcirculation (human, rats, rabbits)
POlHL-09011-15 0001 A research and resource program
in blood - Genetic markers of human blood and gene
mapping (human)
ROlHL-12 138-08 Nutritional regulation of enzyme activity
(rats, human)
ROlHL-12745-10 Enzymes and inhibitors of cholesterol
biosynthesis (rats, human, swine)
ROlHL-12833-09 Genetic and environmental influences on
lung disease (human)
ROlHL-13336-09 Biochemistry and physiology of human
platelets
PSOHL-14217-08 0050 Specialized center of research in
thrombosis - Electron microscopy section (dogs)
P50HL-14217-08 0052 Specialized center of research in
thrombosis - Radioisotope nuclear medicine section
(human, dog)
P50HL-14230-07 0093 A/S SCOR -Lipids, atherosclerosis
and thrombosis - Clinical studies involving cellular lipid
content (human)
** ROlHL-14262-07 Leukocyte proteases and their lung
targets (human, dogs, rabbits)
(contd)
*EKMes nwtinc meltiodohity OR ewers only general projects which preclude Indexing at the specifk level.
"'^laiiK', si^niHcanUy to alOM ubicct.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
BIO
SI
• LO
ROIHL 14739 06 Ihe colt of Itukocytts In thrombotic
disMs* (hum«nc da|>)
POIHl 1498S07 0011 Adaptation (0 tiypoali
Prosli|l(ndins in llw control ol the pulmonary circulation
(animals)
RCIHI Ib22e06 Interaction ol blood cells with librinogen
and tibrin (human, animals)
POIHL 1S48606 0003 Studies on thrombosis
Mechanism and prevention ol tibiinopeplide 6 degradation
(human)
ROIHL IMS) 06 Blood coagulation Platelet plasma
protein interaction (human)
POIHL IS83? 06 0004 Chemical structural predispositions
to lung injury Pioteohrtic activity leucocytes in patients
with obstructive lung disease
P60HL lS999 0b 0008 Miami comprehensive sicMe cell
center Cyanate eftect on host defense Cellular and
humoral (human, guinea pig. rabbits)
POIHL 168M 04 0001 Human red cell membrane in
health and disease Rheology of erythrocyte membrane
(human, amphiuma)
POIHL 16851 04 0003
health and disease
blood rtieology
POIHL- 16851 04 0008
health and disease
(human)
POIHL 16851 04 0009
health and disease
Human red cell membrane in
Modeling membrane mechanics and
Human red cell membrane in
Force balance in red cell interactions
Human red cell membrane in
Blood cell properties in circulatory
regulation (dogs, rabbits)
POIHL 16851 04 0011 Human red cell membrane in
health and disease Ultrastructure laboratory-Core facility
** ROIHL 16938 05 Effect of physical forces on blood (dogs.
human)
** ROlHL-17437-03 Perfusion lung' -Role of traumatized
leukocytes (dogs, human)
** ROlHL-1759603 Lcukocyte-endothelial interactions (rats)
P01HL1781204 0007 Thrombosis and plasma proteins ■
Blood components-Response to endotoxin (dogs, baboons)
** ROlHL-17964-04 The alternate pathway for fibrinolysis
(human)
ROIHL 18012-04 Cellular defects in nocturnal
hemoglobinuria (human)
M POIHL- 18208-04 Center for the study of blood cell
rheology
POIHL- 1820804 0001 Center for the study of blood cell
rheology - Physiological basis of reversible erythrocyte
shape change (human, firefly)
ROlHL-19223-03 Control of cholesterogenesis in leukocytes
and liver (rats, human)
R01HL19777-03 Regulation of hypersensitivity in the lung
(rats, guinea pigs, rabbits, human)
ROlHL-20220-03 Anaphylatoxins as inflammatory and
chemotactic agents (guinea pig. rabbit, human)
ROlHL-20875-02 Chronic obstructive pulmonary disease-
Familial/genetic (human)
** R01HL-20971-10 Membrane glycoproteins of platelets and
leukocytes (human)
** ROlHL-2 1548-01 Pathogenesis of pulmonary
thromboembolic disease (human, mammals)
ROlHL-22053-02 The disordered lipid metabolism of
diabetes mellitus (chickens, mammals, human)
ROlHL-22257-01 Leukokinesis enhancing factor and lung
infections (human, rats)
R23HL-22346-01 Hematological injury and pulmonary
dysfunction (human, mammals)
** R23HL-22437-01 Leukotactic mediators in lung
inflammatory reactions (rats, rabbits, human)
ROlHL-2247001 Liposome myocardial uptake in infarct
and ischemia (dogs. rats, mice)
** ROlHL-2258501 Plasma proteins adsorbed to artificial
organs (human, rabbits)
ROlHL-22738-01 Role of bioelectric potentials in platelet
adherence (bats, rats, hamsters)
ROlHL-23586-06 Pharmacologic control of hypersensitivity
phenomena (human)
ROlHL-23595-01 Experimental emphysema-Depression of
protease inhibitors (rats, hamsters)
BLOOD CELLS, LEUKOCYTES, BASOPHILS
SEE ALSO BLOOD AND RE SYSTEM. MAST CEUS
P50HL-14153-07 0015 Johns Hopkins Lung Center-
Chronic diseases of airways - Kinins and human lung
** R23HL-21089-O2 Localization of mediators in dispersed
lung cells (guinea pigs, human)
" ROlHL-22555-01 Structure and function of platelet
activating factor (rabbits, human)
BLOOD CELLS, LEUKOCYTES, EOSINOPHILS
POlHL-06835-17 0060 Cardiovascular disease -
Ventricular performance experimental models of arterial
hypertension (rats, dogs)
R23HL-21134-02 Immune function and fibrogenesis in
silicosis (guinea pigs)
BLOOD CELLS, LEUKOCYTES, GRANULOCYTES
(GENERAL)
SEE ALSO BLOOD AND RE DISORDERS. LEUKOCYTE
DISORDERS. AGRANULOCYTOSIS
** NOlHB-62970-02 Collection, function and transfusion of
granulocytes
** NOlHB-62971-03 Collection, function and transfusion of
granulocytes
N0IH6 629/2 05
granulocytes
NOIHB 629/3 05
granulocytes
ROIHL 06242 18
ROIHL 147/8 10
Collection, tunctioii nod transfusion of
Collection, lunclmn and transfusion ol
Kinetic studies ol blood (human)
Proteolytic en/ymns and inhibitois in
lung disease (mammals, human)
ROIHL 15685 05 Hemopoietic regulators produced in cell
culture (human, animals)
ROIHL 16254 05 Pathogenesis of bubble and clot
formation (fish)
" P60Ht 1/265 04 0009 Community blood resource center
support Research Developing granulocyte transfusion
therapy (human, rabbit)
POIHL 185/6-03 0009 Thrombosis research program
project Biology of factor VII (human, rabbits, cattle)
POIHL 185 77 03 0001 Lipoproteins Cell surface
interactions Structural studies of serum lipoproteins in
man and dogs
** ROIHL 1972503 Complement induced pulmonary injury
(dogs, rabbits, sheep)
** ROIHL 20807 02 Detection of familial hypercholesterolemia
(human)
POIHL 20994-02 0005 Dynamics of neutrophil elastase in
the lung - Protease inhibitors in pulmonary inflammation
and emphysema (rabbits)
R23HL22621 01 Blood cell mediated pulmonary (human)
ROlHL-23899-01 Flow and flexing at blood/biomaterial
interfaces
BLOOD CELLS, LEUKOCYTES, NEUTROPHILS
POIHL 06314 17 0046
cardiovascular disease
(human, mice)
POlHL-06314 17 0052
cardiovascular disease
Immunologic mechanisms in
Mediators of immune injury
Immunologic mechanisms in
Role of cyclic nucleotides in
neutrophil function (human)
R01HL09125-14 Ultrastructural cytochemistry (human.
chick)
ROlHL-14700-05 Humoral and lung protease-antiprotease
role in obstructive disease (human)
ROlHL-15647-06 Hematopoietic studies of cyclic
hematopoiesis (dogs)
POlHL-15832-06 0004 Chemical-structural predispositions
to lung injury Proteolytic activity leucocytes in patients
with obstructive lung disease
P01HL-1S832-06 0009 Chemical-structural predispositions
to lung injury - Immunology-Enzyme degradation products
of human lung elastin and microfibril
P60HL- 15999-05 0008 Miami comprehensive sickle cell
center - Cyanate effect on host defense -Cellular and
humoral (human, guinea pig, rabbits)
P60HL-16008-06 0015 Wayne State University
comprehensive sickle cell center - Trace elements in sickle
cell disease (human)
POlHL-16769-05 0002 Pathobiologic and host defense
reactions in the lung - Pathogenesis of complement
dependent injury to the lungs (rabbits)
POlHL-16769-05 0004 Pathobiologic and host defense
reactions in the lung - Pathogenesis of Pseudomonas and
Serratia pneumonias (rabbits)
P60HL-I7265-04 0009 Community blood resource center
support - Research-Developing granulocyte transfusion
therapy (human, rabbit)
P50HL-18828-03 0005 Specialized center of research In
thrombosis - Platelet inflammatory factors in thrombosis
(human, guinea pig)
ROlHL-19072-03 Modification of tissue injury in
myocardial infarction (dogs, human)
ROlHL-194 19-03 Cellular interactions with foreign
materials (mammals)
ROIHL- 196 28-03 Mechanisms of pulmonary alveolar
proteinoses (human, rats)
ROlHL-19721-03 Lung inflammation-Lysosomal proteases
and liposomes (human, rabbits)
ROlHL-19741-03 Murine CRD-A model of chronic
pulmonary inflammation (mice, rats)
ROlHL-197 79-03 Biochemical basis of oxygen damage to
lung cells (guinea pigs, rats)
ROIHL- 198 06-03 Chemotactic control of airway phagocytes
(human, rabbits)
ROlHL-20002-03 Pulmonary complications of viral
infections (children)
ROlHL-203 14-02 Host defense against S pheumoniae in
sickle cell disease (human)
POIHL-20994-02 Dynamics of neutrophil elastase in the
lung
POlHL-2099402 0001 Dynamics of neutrophil elastase in
the lung - Dynamics of neutrophil elastase in normal
animals (dogs, rabbits)
POlHL-20994-02 0002 Dynamics of neutrophil elastase in
the lung - Neutrophil and neutrophilic elastase in human
lungs
POlHL-20994-02 0003 Dynamics of neutrophil elastase in
the lung - Neutrophil elastase flux in models of lung
disease (dogs)
POlHL-20994-02 0007 Dynamics of neutrophil elastase in
the lung - The etiology of experimental emphysema (dogs)
R23HL-21 116-02 Mechanisms of membrane and tissue
damage in lung (dogs, rabbits)
R23HL-21 134-02 Immune function and fibrogenesis in
silicosis (guinea pigs)
N2IHI 21805 01 Tutu* cell inlwictioni with vatiular
prostheses (human, rat-., mice)
R23HI 2199/ 01 Pulmonary immunopalhology in Ihn
compromised host (guinea pigs)
ROIHI 22555 01 Structure and tuntlion of pl»l»li-l
activating factor (rabbits, human)
•• R23HI 22823 01 Phagocylit and immune defense
mechanisms of the lung (mice)
ROIHI 23161 01 0005 Biology ol myocardial ischemia
Localization ol r.omplemcnl in myocardial Inlifction (dog)
BLOOD CELLS, LYMPHOCYTES
NOIHB 72919 08 Hemoglobin carhamylalnn in Ihe
treatment of sickle cell anemia (human, dogs)
ROIHL 03180 21 Relation of lymphatics to
cardiopulmonary function (dogs)
POIHL 06314 1/ Immunologic mechanisms in
cardiovascular disease
POIHL 06314 17 0048
cardiovascular disease
(rats, mice)
POIHL 06314 1/ 0050
cardiovascular disease
M
Immunologic mechanism] in
Pathogenesis ol glomerulonephrrtis
Immunologic mechanisms in
Physiologic changes in
lymphocytes (human, mice)
POIHL 06314 17 0052 Immunologic mechanisms in
cardiovascular disease Role ol cyclic nucleotides in
neutrophil function (human)
P01HL06314 17 0059 Immunologic mechanisms in
cardiovascular disease Immunogenetic response to
streptococcal antigens in man
POlHL-06314 17 0064 Immunologic mechanisms in
cardiovascular disease Diabetic vascular disease (human.
rats, mice)
POlHL-06370 17 0004 Cardiopulmonary and renal
pathology research center Lymphocytes in graft rejection
and immune surveillance (human)
ROlHL-07652-14 Destruction of red blood cells in
hemolytic anemias (human, guinea pigs)
ROlHL-09125-14 Ultrastructural cytochemistry (human.
chick)
POlHL-13108-09 0013 Clinical heart transplantation
Cardiomyopathic lymphocyte responsiveness to cultured
endothelium
POlHL-13108-09 0016 Clinical heart transplantation -
Total lymphoid irradiation for immune response (dogs)
ROlHL-13885-08 0006 Cystic fibrosis and pulmonary
disease - Cell mediated immunity and Pseudomonas
infections in cystic fibrosis (human)
ROlHL-13885-08 0008 Cystic fibrosis and pulmonary
disease - Pseudomonas specific activation of alveolar
macrophages (human, rabbits)
P60HL- 15999-05 0008 Miami comprehensive sickle cell
center - Cyanate eflect on host defense-Cellular and
humoral (human, guinea pig. rabbits)
POlHL-16411-04 0003 Blood systems in coagulation and
vessel disease Molecular events involving the late stages
of coagulation (rabbits)
POlHL-16748-05 Cellular and immunological basis of
pulmonary diseases
Cellular and immunological basis
Sarcoidosis -Studies with bronchial
Pathobiologic and host defense
Immunogenetic factors in
POlHL-1674805 0006
of pulmonary diseases
lavage (human)
POlHL-16769-05 0007
reactions in the lung
sarcoidosis (human)
ROlHL-17487-04 Adrenergic-vasoregulation interactions in
hypertension (human)
ROIHL- 17 595-03 Leukocyte-endothelial interactions (rats)
ROlHL-18936-02 Heart preservation and transplantation
studies (rat)
ROIHL- 1965 1-03 Host factors in pathogenesis of
respiratory disease (human, hamsters)
ROlHL-20807-02 Detection of familial hypercholesterolemia
(human)
POlHL-20948-02 0002 Molecular basis of cholesterol
metabolism - LDL pathway in cell lines with informative
properties other than fibroblasts
POlHL-20948-02 0003 Molecular basis of cholesterol
metabolism - LDL pathway in vivo (human, rats, guinea
pigs)
POlHL-20948-02 0004 Molecular basis of cholesterol
metabolism - Genetic analysis of the LDL pathway (human)
POlHL-20948-02 9001 Molecular basis of cholesterol
metabolism - Tissue culture core laboratory
ROlHL-21156-02
lung disease
ROlHL-21565-02
Antitrypsin and other causes of chronic
Pathogenesis of inflammatory lung injury
(rats, rabbits)
ROlHL-22415-01 Mechanisms responsible for disease
severity in asthma (human)
** ROlHL-22456-01 Lipoproteins in bioregulation of the
immune response (mice, human)
ROlHL-22555-01 Structure and function of platelet
activating factor (rabbits, human)
POlHL-22602-01 0003 Pathophysiology of the
endothelium - Mechanisms of endothelial proliferation
(human, animals)
BLOOD CELLS, B LYMPHOCYTES
** POlHL-06314-17 0066 Immunologic mechanisms in
cardiovascular disease - Sensitization, cell-mediated
cytotoxicity, role of lymphocytes (human, mice)
(contd)
'Excludes rautirw melhodokxy OR cavers only general projects which preclude indexing at the specific level.
"Oiieiited significantly to above subject
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number
BLO
52
BLO
** POlHL-0631417 0067 Immunologic mechanisms in
cardiovascular disease - Mitogenic and antigenic activation
of lymphocyte sub-populations
P01HLC6370-17 0001 Cardiopulmonary and renal
pathology research center - The humoral and cellular
mechanisms of allograft rejection (monkeys)
POlHL-06370-17 0014 Cardiopulmonary and renal
pathology research center - Quantitative morphology in
cardiac disease (human, rats, dogs)
POlHL-06370-17 0018 Cardiopulmonary and renal
pathology research center - Cytochemistry and immunology
of lymnhoproliferative disorders (human)
POlHL-06835-17 0060 Cardiovascular disease ■
Ventricular performance experimental models of arterial
hypertension (rats, dogs)
P50HL-14212-07 0014 Correlated studies of pulmonary
fibrosis - Pulmonary lavage cells, secretions in diffuse
intersititial lung disease (human)
P50HL 15061-07 0006 Response of lung to injury ■
Complement synthesis by pulmonary macrophages (guinea
pigs, human)
P60HL-16008-06 0019 Wayne State University
compiehensive sickle cell center - Cell mediated immunity
in sickle cell anemia (human)
P01HL-lb748-05 0002 Cellular and immunological basis
of pulmonary diseases - Immunological function of alveolar
macrophages (rabbits, sheep, mice)
POlHL-16769-05 0010 Pathobiologic and host defense
reactions in the lung - Bronchus associated lymphoid
tissue and delayed hypersensitivity (rabbits)
POIHL 18646-03 0001 Studies basic to heart
transplantation - Individualized regulation of
immunosuppression (dogs, rats)
POlHL-18646-03 0002 Studies basic to heart
transplantation - Detection of rejection (dogs)
POlHL-18646-03 0004 Studies basic to heart
transplantation - Presensitization-Detection, incidence and
clinical significance
POlHL-18646-03 0006 Studies basic to heart
transplantation - Reduction or elimination of existing
presensitization (human, animals)
POlHL-18646-03 0009 Studies basic to heart
transplantation - Pathologic aspects of cardiac allograft
rejection (sheep, dogs)
POlHL-19717-02 0041 Response of the lung to injury -
Cellular immunity in interstitial lung disease (human)
ROlHL-19/41-03 Murine CRD -A model of chronic
pulmonaiy inflammation (mice, rats)
R01HL19779-03 Biochemical basis of oxygen damage to
lung cells (guinea pigs, rats)
ROIHL 20095-03 Role of lymphokines and monocytes in
lung fibrosis (human, guinea pigs, rats)
R23HL-21 134-02 Immune function and fibrogenesis in
silicosis (guinea pigs)
R23HL-21212-02 Alveolar macrophage function in
Pseudomonas infection (dgs)
ROlHL-22301 01 Immunogenetics of chronic pulmonary
inflammation (mice)
ROlHL-22456-01 Lipoproteins in bioregulation of the
immune response (mice, human)
ROlHL-23631-01 Immunogenetic factors in allergic
respiratory diseases (human)
BLOOD CELLS, T LYMPHOCYTES
" POlHL-06314-17 0066 Immunologic mechanisms in
cardiovascular disease - Sensitization, cell-mediated
cytotoxicity, role of lymphocytes (human, mice)
*' POlHL-06314-17 0067 Immunologic mechanisms in
cardiovascular disease • Mitogenic and antigenic activation
of lymphocyte sub-populations
POlHL-06370-17 0001 Cardiopulmonary and renal
pathology research center - The humoral and cellular
mechanisms of allograft rejection (monkeys)
POlHL-0637017 0014 Cardiopulmonary and renal
pathology research center - Quantitative morphology in
cardiac disease (human, rats, dogs)
POIHL 0637017 0018 Cardiopulmonary and renal
pathology research center - Cytochemistry and immunology
of lymphoproliferative disorders (human)
ROIHL 0869615 0019 Orthotopic heart transplantation ■
Suppressor cell stimulation (dogs, mice)
POlHL-1310809 0003 Clinical heart transplantation -
Endomyocardial biopsy pathology
** POIHL 13108 09 0012 Clinical heart transplantation -
Human T cell sheep erythrocyte receptors
POlHL-13108-09 0015 Clinical heart transplantation ■
Antithymocyte globulin analysis and clinical effects
P50HL-I4212-07 0014 Correlated studies of pulmonary
fibrosis - Pulmonary lavage cells, secretions in diffuse
intersititial lung disease (human)
P50HL 1506107 0006 Response of lung to injury -
Complement synthesis by pulmonary macrophages (guinea
pigs, human)
P60HL- 16008-06 0019 Wayne State University
comprehensive sickle cell center - Cell mediated immunity
in sickle cell anemia (human)
R01HL16651-05 Evaluation of steroid therapy in
sarcoidosis (human)
POlHL-16748-05 0002 Cellular and immunological basis
of pulmonary diseases - Immunological function of alveolar
macrophages (rabbits, sheep, mice)
POlHL-16769-05 0008 Pathobiologic and host defense
reactions in the lung - Pulmonary immunocytologic defense
mechanisms against bacteria (human, animals)
POlHL-16769-05 0010 Pathobiologic and host defense
reactions in the lung - Bronchus associated lymphoid
tissue and delayed hypersensitivity (rabbits)
ROlHL-17404-05 Immunologic mechanisms in heart
disease (mice)
POlHL-174 17-05 0003 Experimental lung transplantation
- Methods for detecting lung allograft rejection (dogs)
P01HL18646-03 0001 Studies basic to heart
transplantation - Individualized regulation of
immunosuppression (dogs, rats)
POlHL-18646-03 0004 Studies basic to heart
transplantation - Presensitization-Detection, incidence and
clinical significance
POlHL-18646-03 0006 Studies basic to heart
transplantation - Reduction or elimination of existing
presensitization (human, animals)
P01HL18646-03 0009 Studies basic to heart
transplantation - Pathologic aspects of cardiac allograft
rejection (sheep, dogs)
POlHL-197 17-02 0041 Response of the lung to injury ■
Cellular immunity in interstitial lung disease (human)
ROlHL-19741-03 Murine CRD -A model of chronic
pulmonary inflammation (mice, rats)
ROlHL-19760-01 Cellular immune responses of the lung
(mice, guinea pigs)
ROlHL-19774-03 Pathogenesis of chronic lung disease
(rats, mice, bacteria)
ROlHL-19779-03 Biochemical basis of oxygen damage to
lung cells (guinea pigs, rats)
ROlHL-20095-03 Role of lymphokines and monocytes in
lung fibrosis (human, guinea pigs, rats)
R23HL-21134-02 Immune function and fibrogenesis in
silicosis (guinea pigs)
R23HL-212 12-02 Alveolar macrophage function in
Pseudomonas infection (dgs)
ROIHL 21829-01 Etiology of obstructive airway disease in
children (also monkeys)
ROlHL-22301-01 Immunogenetics of chronic pulmonary
inflammation (mice)
ROlHL-22456-01 Lipoproteins in bioregulation of the
immune response (mice, human)
ROlHL-2363101 Immunogenetic factors in allergic
respiratory diseases (human)
BLOOD CELLS, T LYMPHOCYTES, HELPER
R23HL-21089-02 Localization of mediators in dispersed
lung cells (guinea pigs, human)
BLOOD CELLS, T LYMPHOCYTES, KILLER
P50HL-1600806 0019 Wayne State University
comprehensive sickle cell center ■ Cell mediated immunity
in sickle cell anemia (human)
P01HL18646-03 0003 Studies basic to heart
transplantation - Host responses to xenografts (rodents,
rabbits)
BLOOD CELLS, T LYMPHOCYTES, SUPPRESSOR
ROlHL-22301-01 Immunogenetics of chronic pulmonary
inflammation (mice)
BLOOD CELLS, MONOCYTES
POlHL-06314-17 0067 Immunologic mechanisms in
cardiovascular disease - Mitogenic and antigenic activation
of lymphocyte sub-populations
ROlHL-07652-14 Destruction of red blood cells in
hemolytic anemias (human, guinea pigs)
P50HL-15061-07 0009 Response of lung to injury -
Alveolar macrophages (human, rabbits)
P60HL16005-05 0020 Comprehensive sickle cell center -
Studies of the immunologic defect In sickle cell anemia
(human)
R01HL17581-03 Patent ductus arteriosus and pulmonary
hypertension (dogs)
POlHL-18646-03 0009 Studies basic to heart
transplantation - Pathologic aspects of cardiac allograft
rejection (sheep, dogs)
ROlHL-19731-03 Collagen in interstitial fibrosis of lung
(human)
R01HL-19732-03 Lymphokines in pulmonary
granulomatous inflammation (mice)
** ROlHL-20095-03 Role of lymphokines and monocytes in
lung fibrosis (human, guinea pigs, rats)
** ROlHL-20807-02 Detection of familial hypercholesterolemia
(human)
** ROlHL-22474-01 Cholesterol metabolism and
atherosclerosis (rats, human, rabbits)
ROlHL-22555-01 Structure and function of platelet
activating factor (rabbits, human)
BLOOD CENTERS
SEE BLOOD PRESERVATION. BLOOD BANKS, CENTERS-
RESOURCES-REGISTRIES
BLOOD-CEREBROSPINAL FLUID BARRIER
SEE CEREBROVASCULAR SYSTEM, BLOOD-CEREBROSPINAL
FLUID BARRIER
BLOOD CHEMISTRY
SEE CHEMISTRY. CLINICAL, BLOOD
BLOOD CIRCULATION DYNAMICS
SEE CARDIOVASCULAR FUNCTION, BLOOD CIRCUUTION
DYNAMICS (GENERAL)
BLOOD CIRCULATION TIME
SEE CARDIOVASCULAR FUNCTION. BLOOD CIRCULATION TIME
BLOOD CIRCULATORY SYSTEMS
SEE ADRENAL CIRCULATION
SEE CARDIOVASCULAR SYSTEM
SEE CEREBROVASCULAR SYSTEM
SEE EYE CIRCULATION
SEE GASTROINTESTINAL CIRCULATION
SEE KIDNEY CIRCULATION
SEE LIVER CIRCULATION
SEE RESPIRATORY CIRCUUTION
BLOOD COAGULATION
SEE ALSO BLOOD PLATELETS
SEE ALSO BLOOD STASIS
SEE ALSO CARDIOVASCULAR DISORDERS, EMBOLISM
SEE ALSO CARDIOVASCULAR DISORDERS, HEMORRHAGE
SEE ALSO CARDIOVASCULAR DISORDERS, THROMBOSIS
SEE ALSO VITAMIN K
N01HB-22919-08 Hemoglobin carbamylation in the
treatment of sickle cell anemia (human, dogs)
** R01HL-01662-25 Equilibria in the fibrinogen-fibrin
conversion (human, cattle)
P01HL06314-17 0064 Immunologic mechanisms in
cardiovascular disease - Diabetic vascular disease (human,
rats, mice)
** ROlHL-07835-17 Experimental hypertension and renal
circulation (rats, rabbits)
ROlHL-10582-12 Thrombosis and hemostasis-Analysis,
methods and standards (human, cattle, venom)
** R01HL13198-21 Blood coagulation-Physico-chemical
properties (human, cattle)
P01HL-I3737-07 0026 Assisted circulation - Hemostatic
mechanism (human, dogs)
POlHL-13738-08 0001 Cardiac assist devices and
artificial hearts - Cardiac assist devices (human, sheep)
POlHL-13738-08 0004 Cardiac assist devices and
artificial hearts - Hematological evaluation of prosthetic
materials (calves)
M P50HL-14147-08 Specialized center of research in
thrombosis
" P50HL-14147-08 0013 Specialized center of research in
thrombosis - Mathematical models of blood coagulation
kinetics
** P50HL-14147-08 0014 Specialized center of research in
thrombosis Theoretical models for electrostatic effects in
blood clot formation
P50HL-14147-08 0015 Specialized center of research in
thrombosis - Charge related properties of phospholipid
surfaces in monolayers and vesicles
P50HL-14147-08 0016 Specialized center of research in
thrombosis ■ Nuclear medicine core laboratory (human,
dogs, rats, rabbits)
** P50HL-14147-08 0017 Specialized center of research in
thrombosis - Core coagulation laboratory (human)
** P50HL-1421708 0055 Specialized center of research in
thrombosis - Coagulation section -Platelet coagulant activity)
(human)
POlHL-15195-04 0004 Program project in biological
materials - Biological evaluation and surtace interaction
studies (dogs)
M POlHL-15486-06 Studies on thrombosis
POIHL- 15486-06 0003 Studies on thrombosis -
Mechanism and prevention of fibrinopeptlde 8 degradation
(human)
POlHL-15486-06 0004 Studies on thrombosis -
Thrombosis, intravascuair coagulation, platelet aggregation |
(dogs)
** ROlHL-15491-06 Blood coagulation-Platelet-plasma
protein interaction (human)
** ROlHL-15593-05 Prolonged extracorporeal cardiopulmonary!
support (rats, sheep, rabbits)
** ROIHL- 15887-05 Enzymes of blood coagulation and
fibrinolysis (human)
ROlHL-15958-06 X-ray diffraction analysis of thrombin
and neurotoxin
** P60HL15996-06 0001 Cincinnati comprehensive sickle
cell center - Coagulation mechanisms in sickle cell diseasel
(human)
** ROlHL-16254-05 Pathogenesis of bubble and clot
formation (fish)
M POlHL-16411-04 Blood systems in coagulation and vessel]
disease
** POlHL-16411-04 0001 Blood systems in coagulation and]
vessel disease - Molecular studies of the role of
complement in blood coagulation (human, rabbits)
ROlHL-16582-05 Artificial lungs (dogs)
** ROlHL-16919-05 Proteins of blood coagulation (human.
bovine)
** ROlHL-16955-05 Heparin, blood coagulation and lipid
metabolism (human)
M POlHL-17430-05 Control of coagulation
P01HL17430-05 0001 Control of coagulation - Porcine
von Willebrand's disease
POlHL-1 7430-05 0002 Control of coagulation - Isolation
of ristocetin -von Willebrand factor (swine)
POlHL-17430-05 0005 Control of coagulation - The
activation of prothrombin (human, cattle, dogs)
(contd)
'Excludes routine methodokiey OR covers only general proiects which preclude indexing at the specific level.
"Oneirted significantly to alwve subject
M Grant has subprojeds describing specific research aspects.
See Appendix for investigator's name and grant number.
BLO
ROIHl 17S03'03 ViKuItt bubbl«i in dicompitssion
sickn*si (minlpii. do|. |oit)
ROIHl i;b2b03 Molgculai basis ol colligan plittid
intaiiclKin (human, lat)
ROIHI i;;6903 Naw mathods at studying blood
coaiulation kinatlcs
POIHL W812 04 Thiombosis and plasma piotains
POIHL 1/81204 000b Thiombosis and plasma protams
In viUo systems ol no(mal platelets, white cells, sera
(human)
POIHL 18576 03 Thrombosis research program proiect
POIHL 18b7603 0011 Thrombosis research program
prolact Proteolysis and platelet (unction (human, cattle,
rabbits)
POIHL 18576 03 0014 Thrombosis research program
protect Immunology core
PbOHL 18828 03 Specialiied center ol research In
thrombosis
PbOHL 18828 03 0003 Specialiied center of research in
thrombosis - Structure and lunction of plasma coagulation
inhibitors (human)
PbOHL 1882803 0008 Specialized center ol research in
thrombosis Biochemistry, physiology Platelets and
subcellular platelet particles (human)
PbOHL 18828 03 0009 Specialized center of research in
thrombosis Platelet formation and megakaryocyte cell
biology (guinea pig. human)
ROIHL 18834 04 Metal dependent complex formation in
blood coagulation (human, cattle)
R01HL19982 02 Blood coagulation-Protein metal lonlipid
interactions
ROIHL 2007902 0003 Thromboresistant material Blood
surlace interactions (human, cattle)
ROlHL-2016102 Role ol gamma-carboxyglutamic acid in
blood coagulation (human, cattle)
The mechanism of action of vitamin K
Platelet storage at 22 degrees C
Studies of enzymes in human platelet
ROlHL-20577-03
ROlHL-20818-02
(human)
R23HL-21490-02
membranes
** ROlHL-2154002 Specific inhibitors of coagulation and
fibrinolysis (rats, rabbits, dogs)
ROlHL-2176901 Blood compatible benzamidine containing
polymers
ROlHL-22270-01 Platelet glycoprotein (human)
ROlHL-2255501 Structure and function of platelet
activating factor (rabbits, human)
** ROlHL-2277101 Thrombogenic phospholipid surfaces
(cattle)
ROlHL-2287501 Crotalase-Chemistry, physiology, clinical
potential (rats, rabbits)
BLOOD COAGULATION, ACTIVATION PRODUCT
SEE ALSO BLOOD COAGULATION, FACTOR XI
SEE ALSO BLOOD COAGULATION, HAGEMAN FACTOR
R01HL13423-08 Structure-function studies of plasminogen
and plasmin (human)
** ROlHL-15817-06 Plasminogen activators from tissues
(human, pig, cattle)
ROlHL-16633-04 Chemistry and biology of factor IX
activator (human, mice, rats)
ROlHL-17402-04 Mechanism of contact activation of
intrinsic clotting (human)
** ROlHL-18859-03 Biochemistry of human factor XI (human)
ROlHL-20846-02 Purification of bovine plasminogen
proactivator
ROlHL-21592-01 Lipoproteins and coagulation factors in
atherosclerosis (pigeons)
BLOOD COAGULATION, ANTICOAGULANTS
SEE ALSO BLOOD COAGUUTION. ANTITHROMBIN
SEE ALSO BLOOD COAGUUTION. HIRUDEN
SEE ALSO BLOOD COAGULATION. THROMBOPOIESIS
INHIBITORS
ROlHL-01601-30 Blood coagulation and hemorrhagic
disease (horseshoe crabs)
ROlHL-01661-27 Hemostatic mechanisms (human)
** ROlHL-02212-23 Coagulation of blood (human)
ROlHL-02254-23 Blood coagulation and hemorrhagic
disease (human, animals)
POlHL-06312-17 0030 Surgical cardiology - Total
artificial heart (calves)
POlHL-06350-17 0018 Hemostasis research program
project - Varients of factors IX (human, cattle)
ROlHL-07835-17 Ejperimental hypertension and renal
circulation (rats, rabbits)
ROlHL-09163-13 Control mechanisms in hemostasis
(human)
*• ROlHL-10582-12 Thrombosis and hemostasis-Analysis.
methods and standards (human, cattle, venom)
** POlHL-11310-12 0103 Mechanisms of cardiovascular
disease - Heparin-Metabolism and function
POlHL-11414-11 0033 Thrombosis and atherosclerosis
program - Human coumarin-induced prothrombin
** POlHL-11414-11 0035 Thrombosis and atherosclerosis
program - Mechanism of action of vitamin K (rats)
ROlHL-1 1880-10 Physiology and pathology of blood
platelets (human, dogs)
POlHL-13330-08 0056 Mechanical circulatory support
Blood compatibility linings (calves)
ROlHL-13587-06 Synthesis of renin inhibitors and analog
phosphatides (rats)
53
POIHL 13738 08 0002 Ctrdlic aiiiti devices and
iriltlciil hearts Total replacement with Ktiliclal heart
(cahres, sheep, ponies)
POIHL 13738 08 0003 Cardiac assist devices and
artilicial henrls Pathophysiological ollects ol the artlllclil
heart (calves)
ROIHL 13/54 08 Postoperative thromboembolism in
surgical patients (human)
P50HI 1418/07 0008 Pulmonary SCOR -Chemical
mediators in pulmonary vascular responses Pulmonary
thromboembolism (dogs, human)
ROIHL 14/39 06 Ihe role ol leukocytes in thrombotic
disease (human, dogs)
ROIHL 1484/0/ Mechanism ol action ol vitamin K and
anticoagulants (rats)
ROIHL 14992 0/ Mechanism ol thrombin action (human)
POIHL 15596 05 001/ Coagulation, fibrinolysis,
hemostasis and hepatitis Heparin and antithrombin III
ROIHL 1561905 Regulation ol prothrombin synthesis in
cultured cells (rats)
ROIHL 15698 12 Factors affecting the action of
anticoagulants (rats, human)
ROIHL 15/2806 The carbohydrate of the blood clotting
glycoproteins (mammals)
ROIHL 16461 05 Late results of valve replacement
Computer analysis (human)
ROIHL 1658205 Artificial lungs (dogs)
ROIHL 16634 13 Regulation of metabolism in fibroblasts
and platelets (human, rabbits, sheep)
ROIHL 1691905 Proteins of blood coagulation (human,
bovine)
ROIHL 1695505 Heparin, blood coagulation and lipid
metabolism (human)
P60HL1726504 0006 Community blood resource center
support Research-Evaluation of platelet transfusions
(human, dog)
ROlHL-17408-03 Fresh blood rheology-Relation to
cardiovascular risk (human)
ROlHL-17479-04 Blood storage-The production of
cardiotoxic material (dogs, human, swine)
ROlHL-17513-04 Role of PF-4 in detecting and promoting
thrombosis (human, primates)
ROlHL-17726-03 Bacterial heparinasc in diagnostic
coagulation studies
ROlHL-17747-04 Endothelial injury and regeneration (rats)
ROlHL-17752-03 Purified human clotting factor IX-
Immunologic studies (human)
ROlHL-17964-04 The alternate pathway for fibrinolysis
(human)
' ROlHL-18068-02 Chemistry and activity of homologous
heparin fractions (rodents)
' ROlHL-18245-03 Transition state analog inhibitors of
thrombin (human, cattle)
POlHL-18576-03 0003 Thrombosis research program
project - Biocompatible materials
POlHL-18576-03 0010 Thrombosis research program
project ■ Evaluation of non-thrombogenic materials (cattle)
' POlHL-18576-03 0012 Thrombosis research program
project - Synthetic anticoagulant and thrombolytic agents
(dogs)
POlHL-18576-03 0013 Thrombosis research program
project - Early warning and monitoring test systems in
thrombotic disease (human)
Cerebral blood flow after cardiac arrest
Organization of arterial ground substance
ROlHL-18590-03
(dogs, monkeys)
ROlHL-18625-03
(cattle)
ROlHL-18672-03 Dynamic studies of clot structure
formation (human)
ROlHL-18738-02 Prevention of postoperative venous
thrombi (human, cattle)
ROlHL-18764-03 Biosorbable thromboresistant surfaces
(dogs, rats, swine, human)
ROlHL-18815-03 Surgical vascular disorders (human.
dogs)
ROlHL-19105-02 Detection and adherence of fibrin
monomer complexes (human)
P50HL-191 55-02 0004 Pathophysiology of pulmonary
edema - Physical and chemical effects of multiple
pulmonary emboli (sheep)
ROlHL-19255-03 Evaluation of diagnostic clinical
hemorrheology (human)
ROlHL-19322-03 Role of pituitary hormones in the action
of vitamin K (rats)
ROlHL-19331-03 Hirudin isolation and utilization (leeches)
ROlHL-19350-02 Prevention of thrombosis by applied
electric fields (sheep)
ROlHL-19772-02 Role of warfarin metabolism in
antivitamin K activity (rats)
ROlHL-19820-02 The chemistry and biological effects of
heparin (Rhesus, human, other mammals)
ROlHL-20073-02 Blood compatible materials by fluid
perfusion (human, dogs)
ROlHL-20577-03 The mechanism of action of vitamin K
R01HL-2n39-02 Molecular biology of factor XIII (human)
R23HL-21271-02 Extracorporeal circulation and protein
denaturation (human)
ROlHL-21403-02 Blood clotting kinetics studied by
radioimmunoassay (human)
ROlHL-214 76 02 Anticoagulant drug absorption
interactions (rats)
UlU
ROIHl 21540 0? Specific inhlbilori of coagulation and
llbrlnohftit (ratt. rabbit%, do|il
ROIHI 21544 02 Proteins ol coagulation and Hagenian
factor pathways (human, goats)
HOIHI 21548 01 Pathogenesis ol pulmonary
Ihionibonmtjohc disease (human, mammals)
ROIHI 2l/(<)0'i Heparin and heparan tullate Slruclurt
and activity Ibeel. hog)
" ROIHI 22035 01 Molecular modification ol heparin by
chemical means (sheep)
ROIHI 221 19 01 Biochemistry ol platelet function in
thrombose and cell growth (rabbits)
•• ROIHI 17ni 01 A new source ol hyaluronidase and
anticoagulants (leeches)
ROIHI 22402 01 Heparin biophysical, chemical and
biological aspects (mice, human)
ROIHL 22980 01 Kinetic and mechanistic studies ol blood
coagulation (human, cattle)
ROIHI 23899 01 Flow and flexing at blood/biomalerial
interfaces
** NOIHV 32919 12 Material development and testing
heparinizalion processes
NOIHV 72939 01 Develop and evaluate left heart assist
blood pumps (human, calves, pigs)
BLOOD COAGULATION, ANTICOAGULANTS,
PLATELET AGGREGATION INHIBITORS
POIHL 06350 17 0019 Hemostasis research program
project Microcirculation (human, rats, rabbits)
ROIHL 08888 12 Cooperative study of drugs and coronary
heart disease (men)
ROIHL 10445 09 Cooperative study of drugs and coronary
heart disease (men)
ROIHL 10705 09 Cooperative study of drugs and coronary
heart disease (men)
ROIHL 11372-08 Cooperative study ol drugs and coronary
heart disease (men)
POlHL-11414 11 0004 Thrombosis and atherosclerosis
program - Platelet function and nonthrombogenic surfaces
(human)
** ROlHL-11775-11 Platelet mechanisms in disease (human,
primates)
R01HL-1194510 Synthesis of artificial lung and kidney
systems (sheep, mice, swine)
ROIHL 13036-08 Coronary thrombosis -Effects on
myocardium and in vivo detection (dogs, monkeys)
ROlHL-13629-08 Hemorrhagic diseases (human)
P50HL 14147-08 0001 Specialized center of research in
thrombosis - Role of aspirin, other anti platelet agents in
platelet lunction (rat, human)
P50HL-14217-08 0054 Specialized center of research in
thrombosis - Coagulation section -Platelet aggregation
(human, pig, rabbit, dog)
P50HL-14217-08 0055 Specialized center of research in
thrombosis - Coagulation section-Platelet coagulant activity
(human)
" P50HL-14217-08 0058 Specialized center of research in
thrombosis - Mechanisms of induction and inhibition of
platelet reaction (human, pig)
P50HL-14217-08 0062 Specialized center of research in
thrombosis - Coagulation section -Factor VIII and Factor XII
(human, cattle)
P50HL-14230-07 0097 A/S SCOR -Lipids, atherosclerosis
and thrombosis - Studies of circulating platelet aggregates
(human)
** ROlHL-14344-07 Platelet function and adenine nucleotide
metabolism (human)
ROlHL-15374-03 Cooperative study of drugs and coronary
heart disease (human)
ROlHL-15580-06 Humoral control of pulmonary and
systemic circulation (animals)
ROlHL-15593-05 Prolonged extracorporeal cardiopulmonary
support (rats, sheep, rabbits)
ROlHL-15681-06 Coronary flow studies of partially
obstructed vessels (dogs)
POlHL-16387-04 0005 The blood vessel and
thrombogenesis - Fluid engineering considerations in
thrombogenesis
ROlHL-16582-05 Artificial lungs (dogs)
" ROlHL-16720-02 Platelet aggregation (human)
P60HL-1 7265-04 0006 Community blood resource center
support - Research -Evaluation of platelet transfusions
(human, dog)
POlHL-17430-05 0007 Control of coagulation - Platelet
adhesion, aggregation, ultrastructure in flowing blood
(human, animals)
P50HL-17648-04 0023 Study of ischemic heart disease -
Chemical mediators of inflammation in acute myocardial
infarction (mammals)
ROlHL-17747-04 Endothelial injury and regeneration (rats)
ROlHL-17921-04 Peroxy radicals to prostaglandins in
vessels and lung
ROlHL-18288-04 Intraoperative protection of the
myocardium (dogs, rats)
R01HL-18502-03 Enzymatic regulation of platelet function
(human)
P01HL18576-03 0003 Thrombosis research program
project - Biocompatible materials
POlHL-18576-03 0007 Thrombosis research program
project - Relationships between coagulability and
thrombosis (human, animals)
POlHL-18576-03 0010 Thrombosis research program
project - Evaluation of non-thrombogenic materials (cattle)
(contd)
^Excludes routine methodok)gy OR covers onhi general projects which preclude indexing at the specific levet-
**0neflted significantly to above subject.
M Grant has subprojects descnbing specihc research aspects
See Appendix for investigator's name and grant number.
BLO
R01HL18644-03 Prosthesis for aortocoronary bypass
(dogs, baboons)
** POlHL-18645-03 0006 Biology of the artery wall and
atherosclerosis - The platelet and atherosclerosis (monkeys,
baboons)
ROlHL-18764-03 Biosorbable thromboresistant surfaces
(dogs, rats, swine, human)
P01HL18827-02 0003 Platelet vessel wall interactions in
thrombogenesis - Tumor cell and platelets In
thrombogenesis and metastasis (human, animals)
POlHL-1882702 0005 Platelet vessel wall interactions in
thrombogenesis - Platelet vessel wall interactions in
thrombogenesis (human)
P01HL1882702 0006 Platelet vessel wall interactions in
thrombogenesis ■ Platelet immune injury in man
P50HL-18828-03 0001 Specialized center of research in
thrombosis - Membrane biology and hemostasis (human)
P50HL-18828-03 0005 Specialized center of research in
thrombosis - Platelet inflammatory factors m thrombosis
(human, guinea pig)
** ROlHL-18932-03 Brain microcirculation observed in vivo
after trauma (mice)
ROlHL-18937-03 Cyclic nucleotides and calcium in
platelets (human)
ROIHL- 1900 1-03 Atherosclerosis in bleeder and drug
treated subjects (pigs)
ROlHL-19055-03 Platelet function during extracorporeal
perfusion (human, mammals)
** R01HL19n2-03 Atherosclerosis studies (monkeys)
ROIHL 19278-03 Ristocetin induced platelet aggregation
(human)
ROIHL 19996-02 Role of membrane proteins in platelet
function (human, rabbits)
** ROlHL-2014002 Glycoproteins of platelet membrane and
platelet function (human)
** ROlHL-20251-02 A novel approach to nonthrombogenic
polymer surfaces (sheep, cattle)
ROlHL-20313-02 Surface-induced thrombosis-Modification
of albumin variants (human, goat)
R23HL-2 1298-02 Coronary vasomotion (dogs, pigs)
** ROlHL-21533-02 Platelet inhibitor drug in coronary surgery
(human)
POlHL-22163-01 0003 Surface thrombogenesis-
Mechanisms and prevention - In vivo mechanisms of
biomaterial thrombogenesis and its prevention (baboons)
** ROlHL-22445-01 Platelet inhibitors-Effect on coronary
bypass grafts (dogs)
ROlHL-22527-01 Prostacyclin-thromboxanes In the
cardiovascular system (human, rabbits)
POlHL-22602-01 0001 Pathophysiology of the
endothelium - Platelet-endothelial interactions in vitro
(human, cattle)
ROlHL-22612-01 Stabilized prostacyclins to treat vascular
disease
" ROlHL-22627-01 An inhibitor of platelet adhesion to
artificial organs (human)
** ROlHL-22951-01 Studies on the affect of vitamin E on
platelets (human, rats)
ROlHL-231 14-01 Control of platelet aggregation in shock
(dogs, rabbits)
ROlHL-23603-01
disease (rats)
** NOlHV-42984-05 Interactions of modified biopolymers with
blood (humans, rats)
NOlHV-52901-06 Aspirin-myocardial infarction study
NOlHV-52941-04 Center for aspirin-myocardial infarction
study (human)
BLOOD COAGULATION, ANTIFIBRINOLYTIC
AGENTS
P50HL-1421708 0049 Specialized center of research in
thrombosis - Fibrinolysis section -Clinical studies
POlHL-15596-05 0001 Coagulation, fibrinolysis,
hemostasis and hepatitis - Defibrination (human)
P01HL18574-03 0006 Lipoprotein methodology and
biomedical applications - Lipoprotein transformation,
lipolytic enzymes, diet and lipid lowering agents
ROlHL-20846-02 Purification of bovine plasminogen
proactivator
ROIHL'2 1540-02 Specific inhibitors of coagulation and
fibrinolysis (rats, rabbits, dogs)
ROlHL-22289-01 Endothelial cell mediated fibrinolysis
(rabbits)
ROlHL-22573-01 Treatment of post surgical
vasoconstriction (dogs, monkeys, human, rats)
ROIHL 22875-01 Crotalase -Chemistry, physiology, clinical
potential (rats, rabbits)
BLOOD COAGULATION, ANTITHROMBIN
SEE ALSO BLOOD COAGULATION, FIBRIN
SEE ALSO BLOOD COAGULATION, HEPARIN CO-FACTOR
** R01HL02262 23 Mechanisms regulating plasma proteins
and solutes (human, dogs)
R01HL03424-21 Formation and properties of prothrombin
derivatives (human, animals)
ROlHL-0436619 Plasminogen -Activation and structure-
function relations (mammals, birds)
ROlHL-09739-13 Biophysical studies of proteins (human)
POlHL'11310-12 0103 Mechanisms of cardiovascular
disease - Heparin-Metabolism and function
ROlHL-12820-09 In vitro regulation of prothrombin
activation
ROIHL 13160-08 Human thrombin (also cattle)
Morphogenesis of hypertensive vascular
54
** ROlHL-1499207 Mechanism of thrombin action (human)
** P01HL15596-05 0017 Coagulation, fibrinolysis,
hemostasis and hepatitis - Heparin and antithrombin III
ROlHL'15887-05 Enzymes of blood coagulation and
fibrinolysis (human)
** R01HL-16238-05 Protein structure in coagulation and
fibrinolysis (human)
ROlHL-16355-05 Reactions of thrombin and collagen with
platelets (human)
** ROlHL-16919-05 Proteins of blood coagulation (human,
bovine)
R01HL-16955-0S Heparin, blood coagulation and lipid
metabolism (human)
R01HL17513-04 Role of PF-4 in detecting and promoting
thrombosis (human, primates)
POlHL-1781204 0004 Thrombosis and plasma proteins -
Serum-platelet interaction (human)
ROlHL-18333-05 Thrombogenesis and hemostatic balance
(rabbits, human)
POlHL-18576-03 0011 Thrombosis research program
project - Proteolysis and platelet function (human, cattle.
rabbits)
P50HL-18828-03 0003 Specialized center of research in
thrombosis - Structure and function of plasma coagulation
inhibitors (human)
" ROlHL-19131-04 Hypercoagulability and assays for its
protection (human)
** ROlHL-20337-02 Thromboembolic diseases (human)
** ROlHL-211 13-01 Control mechanisms in coagulation
(cattle)
ROlHL-21403-02' Blood clotting kinetics studied by
radioimmunoassay (human)
ROlHL-22035-01 Molecular modification of heparin by
chemical means (sheep)
ROlHL-221 19-01 Biochemistry of platelet function in
thrombosis and cell growth (rabbits)
R01HL-22227-01 A new source of hyaluronidase and
anticoagulants (leeches)
ROlHL-22471-01 Biochemistry of prothrombin quick
(human)
R23HL-22799-01 Interaction of the complement and
coagulation systems (monkeys)
ROlHL-22996-01 Venom proteases-Action on plasma
protease inhibitors (human)
BLOOD COAGULATION, ANTITHROMBOGENIC
SURFACE
R01HL-0ie48-31 Blood coagulation and hemophilia (dogs.
swine)
POlHL-06370-17 0013 Cardiopulmonary and renal
pathology research center - Morphologic analysis of
vascular prosthesis (human, dogs)
ROlHL-10582-12 Thrombosis and hemostasis-Analysis,
methods and standards (human, cattle, venom)
** POlHL-11414-11 0004 Thrombosis and atherosclerosis
program - Platelet function and nonthrombogenic surfaces
(human)
ROlHL'11775-11 Platelet mechanisms in disease (human,
primates)
ROlHL-1 1945-10 Synthesis of artificial lung and kidney
systems (sheep, mice, swine)
M POlHL-13330-08 Mechanical circulatory support
POlHL-13330-08 0034 Mechanical circulatory support - In
vivo test and evaluation of left ventricular bypass pumps
(human, cattle)
** POlHL-13330-08 0056 Mechanical circulatory support -
Blood compatibility linings (calves)
ROlHL-13426-09 Left ventricular bypass for myocardial
infarction (cattle, human)
** P01HL13737-07 0002 Assisted circulation - U-shaped
mechanical auxiliary ventricle (dogs)
POlHL-13737-07 0032 Assisted circulation - The dynamic
aortic patch (human, dogs)
P01HL13738-08 0004 Cardiac assist devices and
artificial hearts - Hematological evaluation of prosthetic
materials (calves)
P50HL-14147-08 0003 Specialized center of research In
thrombosis - Surface thrombogenicity and phospholipid
vesicle physical properties
POlHL-1519604 0002 Program project in biological
materials - Structural and surface characterization
POlHL-15195-04 0004 Program project in biological
materials - Biological evaluation and surface interaction
studies (dogs)
ROlHL-15593-05 Prolonged extracorporeal cardiopulmonary
support (rats, sheep, rabbits)
ROlHL-15668-06 Extracorporeal respiratory gas exchange-
A new approach (dogs)
ROlHL-16921-05 Synthetic hydrogels as blood tolerable
materials
P60HL-17269-04 0030 National heart and blood vessel
research and demonstration center - Cardiovascular
engineering laboratories (human)
POlHL-17430-05 0007 Control of coagulation - Platelet
adhesion, aggregation, ultrastructure in flowing blood
(human, animals)
** R01HL17623-05 Initial events in thrombus formation on
surfaces (human, rats)
ROlHL-1808403 Artificial heart and related problems
(calves)
ROlHL-185 19-03 Albumin, endothelium and
hemocompatibility (human, dog, cattle, rabbit)
M P01HL18576-03 Thrombosis research program project
BLO
POlHL-18576-03 0003 Thrombosis research program
project - Biocompatible materials
POlHL-18576-03 0010 Thrombosis research program
project - Evaluation of nonthrombogenic materials (cattle)
ROlHL-18644-03 Prosthesis for aortocoronary bypass
(dogs, baboons)
POlHL-1864503 0006 Biology of the artery wall and
atherosclerosis - The platelet and atherosclerosis (monkeys.
baboons)
ROlHL'18764-03 Biosorbable thromboresistant surfaces
(dogs, rats, swine, human)
ROlHL-19055-03 Platelet function during extracorporeal
perfusion (human, mammals)
ROlHL-19173-03 Analysis of blood trauma from
microporous oxygenators (human, dogs, rabbits)
ROlHL-19350-02 Prevention of thrombosis by applied
electric fields (sheep)
ROlHL-19419-03 Cellular interactions with foreign
materials (mammals)
ROlHL-20073-02 Blood compatible materials by fluid
perfusion (human, dogs)
ROlHL-2007902 Thromboresistant material
ROIHL 20079-02 0001 Thromboresistant material Active
and passive thromboresistant surfaces
ROlHL-2007902 0002 Thromboresistant material -
Thromboresistant materials (sheep)
ROIHL 20079-02 0003 Thromboresistant material ■ Blood
surface interactions (human, cattle)
ROlHL-20251'02 A novel approach to nonthrombogenic
polymer surfaces (sheep, cattle)
ROlHL-20313-02 Surface-induced thrombosis-Modification
of albumin variants (human, goat)
ROlHL-20356-02 Development and evaluation of an
artificial heart (calves)
ROlHL-21001-01
vascular grafts
ROlHL-2 11 94-02
Protein and thrombus deposition on
Development of antithrombogenic plastic
'Excludes routine methodotogy OR covers only general projects which preclude indexing
"Onentwl >if nificantly to above lubject.
biomaterials
R23HL-21271-02 Extracorporeal circulation and protein
denaturation (human)
R23HL-21805-01 Tissue cell Interactions with vascular
prostheses (human, rats, mice)
ROlHL-22 110-02 Healing complications in vascular
grafting (dogs)
M POlHL-22163-01 Surface thrombogenesis-Mechanisms and
prevention
** POlHL-22163-01 0001 Surface thrombogenesis-
Mechanisms and prevention - Initial blood protein and
platelet interactions with biomaterials (baboons)
** POlHL-22163-01 0002 Surface thrombogenesis-
Mechanisms and prevention - Laser-scattering detection of
microemboli in blood flow (baboons)
** POlHL-22163-01 0003 Surface thrombogenesis-
Mechanisms and prevention - In vivo mechanisms of
biomaterial thrombogenesis and its prevention (baboons)
" POlHL-2216301 9001 Surface thrombogenesis-
Mechanisms and prevention - Polymers for studing blood-
material interactions core
ROlHL-22338-01 Platelet adhesion and aggregation in a
flow chamber (human)
R01HL2245501 Platelet concentration in the marginal
layer (dogs, human)
ROlHL-22585-01 Plasma proteins adsorbed to artificial
organs (human, rabbits)
** ROlHL-22627-01 An inhibitor of platelet adhesion to
artificial organs (human)
** ROlHL-23899-01 Flow and flexing at blood/biomaterial
interfaces
NOlHV-12060-18 Tissue cultured endothelium for vascular
prosthetic devices (human, animals)
NOlHV-32919-12 Material development and testing
heparinization processes
" N01HV-3295008 Blood compatible poly-electrolytes
** NOlHV-32953-10 Materials compatible with blood (dogs)
NOlHV-32907-04 Interactions of platelets with collagens
(human, mammals)
NOlHV-72934-01 Development of a left heart assist blood
pumps (human, cattle)
NOlHV-72936-00 Left heart assist device development
(human, cattle)
NOlHV-72938-01 Development of a left heart assist blood
pump
NOlHV-7293901 Develop and evaluate left heart assist
blood pumps (human, calves, pigs)
NOlHV-81388-20 Microfiber substrate for growth of intimal
linings in circulatory assist devices
BLOOD COAGULATION, CLOT RETRACTION
ROlHL-16938-05 Effect of physical forces on blood (dogs,
human)
M POlHL-17812-04 Thrombosis and plasma proteins
** POlHL-17812-04 0004 Thrombosis and plasma proteins -
Serum-platelet interaction (human)
POlHL-17812-04 0005 Thrombosis and plasma proteins -
In vitro systems of normal platelets, white cells, sera
(human)
ROlHL-18030-04 The role of contractile proteins in
platelets (human, rabbits)
ROlHL-20 106-02 Coupling of platelet contractile proteins
to fibrin (human)
(contd)
at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
BIO
•LOOO COAGULATION, CLOniNO FACTORS
(OENEKAl)
** ROIHI lObS? 12 Thrombojij »nd h«mosl«sis Aimlyjis,
mtthods and sttndicds (humin. cattlt. venom)
ROIHL 12820 09 In vilio ra|ul<lion of piolhrombin
•ctivttion
•• P50HL 1414/ 08 0018 Specmliigd cenlei ot f«seaich in
thrombosis Biocbtmical aspects ot platelet function in
thrombosis and cell iiowth (human)
PbOHL 1421708 0054 Specialiied center ot research in
thrombosis Coagulation section Platelet aggregation
(human, pig. rabbit, dog)
•* PiOHL 14217 08 OObb Specialiied center ol research in
thrombosis Coagulation section Platelet coagulant activity
(human)
ROIHL 14847 07 Mechanism ot action ot vitamin K and
anticoagulants (rats)
ROIHI 14992 07 Mechanism of thrombin action (human)
•* ROIHL 1572806 The carbohydrate ot the blood clotting
glycoproteins (mammals)
P60HL 1599606 0001 Cincinnati comprehensive sickle
cell center Coagulation mechanisms in sickle cell disease
(human)
P60HL 17265 04 0003 Community blood resource center
support Research Human factor IX-Role in intrinsic
clotting (also baboons, dogs)
P60HL 17265 04 0007 Community blood resource center
support ■ Research Massive transfusion and trauma
(human)
" ROIHL 1740204 Mechanism of contact activatron of
intrinsic clotting (human)
** ROIHL 1867203 Dynamic studies of clot structure
formation (human)
ROIHL 18859-03 Biochemistry ot human (actor XI (human)
P50HL 19155-02 0004 Pathophysiology of pulmonary
edema Physical and chemical effects of multiple
pulmonary emboli (sheep)
** ROlHL-1927203 Studies on the Passovoy factor (human)
ROlHL-20313-02 Surface-induced thrombosis -Modification
of albumin variants (human, goat)
ROlHL-2100101 Protein and thrombus deposition on
vascular grafts
** ROlHL-21543-02 Structure-function relation of blood
clotting proteins (rabbits)
** ROIHL 21544-02 Proteins of coagulation and Hageman
factor pathways (human, goats)
** ROlHL-21592-01 Lipoproteins and coagulation factors in
atherosclerosis (pigeons)
** ROlHL-2253001 Active site studies on blood proteases
(human)
ROlHL-23899-01 Flow and flexing at blood/biomaterial
interfaces
BLOOD COAGULATION, CRYOFIBRINOGEN
P50HL-14147-08 0006 Specialized center of research in
thrombosis - Clearance mechanisms of coagulation
moieties (human, rabbits, rodents)
POlHL-17419-04 0001 Studies on mechanisms of
hemostasis - Structure and metabolism of fibrinogen
(human)
BLOOD COAGULATION, FACTOR V
ROlHL-03424-21 Formation and properties of prothrombin
derivatives (human, animals)
R01HL-12820-09 In vitro regulation of prothrombin
activation
** POlHL-13108-09 0014 Clinical heart transplantation -
Platelets and coagulation in accelerated graft coronary
atherosclerosis
P50HL-14147-08 0013 Specialized center of research in
thrombosis ■ Mathematical models of blood coagulation
kinetics
** POlHL-15596-05 0018 Coagulation, fibrinolysis.
hemostasis and hepatitis - Increased plasma lipids on
blood coagulation and thrombosis (human, animals)
POlHL-17430-05 0005 Control of coagulation - The
activation of prothrombin (human, cattle, dogs)
POIHL 17430-05 0006 Control of coagulation - Activation
fragments of prothrombin in vitro and in vivo (human,
dogs, cattle)
POIHL- 178 12-04 0004 Thrombosis and plasma proteins
Serum-platelet interaction (human)
ROlHL-18435-03 Properties of thrombin and Ac-globulin
(human, animals)
** POIHL- 1882 7-02 0007 Platelet vessel wall interactions in
thrombogenesis Biochemistry and role factor V in
thrombogenesis (human, cattle)
P50HL- 18828-03 0001 Specialized center of research in
thrombosis - Membrane biology and hemostasis (human)
P50HL18828-03 0002 Specialized center of research in
thrombosis - Endothelial cell biology (human, guinea pig)
ROIHL 18834-04 Metal-dependent complex formation in
blood coagulation (human, cattle)
** ROlHL-18852-03 Biochemical studies on the blood
coagulation process (human, cattle)
R01HL-19I31-04 Hypercoagulability and assays for its
protection (human)
ROlHL-21403-02 Blood clotting kinetics studied by
radioimmunoassay (human)
ROlHL-22471-01 Biochemistry of prothrombin quick
(human)
R23HL-22799-01 Interaction of the complement and
coagulation systems (monkeys)
•Exdudes routine melhodokigy OR covers onhr general projects which preclude indexing
Onented significantly to above subject.
SS
ROIHL 2287501 Crolalase Chemistry, physiology, cliniial
potential (rats, rabbits)
ROIHL 72955 01 metres o( prothrombin activation
BLOOD COAGULATION, FACTOR VII
HOIHI 15596 05 0016 Coagulation, fibrinolysis.
hemostasis and hepatitis Hepatitis B antigen in whole
blood, plasma and plasma fractions (human, monkeys)
POIHL 15596 05 001/ Coagulation, fibrinofysis.
hemostasis and hepatitis Heparin and antilhiombin III
** POIHL 1559605 0018 Coagulation, fibrinofysis.
hemostasis and hepatitis Increased plasma lipids on
blood coagulation and thrombosis (human, animals)
ROIHL 15728 06 The carbohydrate of the bfood clotting
glycoproteins (mammals)
•* ROIHL 1691905 Proteins of blood coagulation (human,
bovine)
ROIHL 16955-05 Heparin, blood coagulation and lipid
metabolism (human)
" POIHL 1857603 0009 Thrombosis research program
project Biology of factor VII (human, rabbits, cattle)
ROIHL 197 72 02 Role of warfarin metaboMsm in
antivitamin K activity (rats)
ROIHL 19982 02 Blood coagulation Protern metal ion lipid
interactions
•* ROIHL 21 113 01
(cattle)
ROIHL 22530-01
(human)
R01HL22875-01 Crotalase-Chemistry, physiology, clinrcal
potential (rats, rabbits)
** ROlHL-22980-01 Kinetic and mechanistic studies of blood
coagulation (human, cattle)
BLOOD COAGULATION, FACTOR VIII
SEE ALSO BLOOD COAGUUTION DISORDERS, HEMOPHILIA
" NOlHB-53016-05 Cooperative study of factor VIII inhibitors
in patients with hemophilia
** NOlHe-5301804 Cooperative studies of factor VIII
inhibitors in patients with hemophilia
** NOlHB-530 19-06 Cooperative study of factor VIII inhibitors
in patients with hemophilia
** NOlHB-53020-04 Cooperative study of factor VIII inhibitors
in patients with hemophilia
" NOlHB-53021-05 Cooperative study of factor VIII inhibitors
in patients with hemophilia
** NOlHB-53023-04 Cooperatrve study of factor VIII inhibitors
in patients with hemophilia
** NOlHB-53024-04 Cooperative studies of factor VIII
inhibrtors in patients with hemophilia
** NOlHB-53025-05 Cooperative studies of factor VIII
inhibitors in patients with hemophilia
" NOlHB-53035-04 Factor VIII inhibitors in patients with
Control mechanisms in coagulation
Active site studies on blood proteases
hemophilia
ROlHL-01648-31
swine)
ROlHL-01661-27
ROlHL-02254-23
Blood coagulation and hemophilia (dogs.
Hemostatic mechanisms (human)
Blood coagulation and hemorrhagic
disease (human, animals)
POlHL-031 74-23 0005 Mechanisms of acute vascular
reaction to injury - Renal small vessel didease-Cell and
matrix response (human, mice)
■ POlHL-06350-17 0005 Hemostasis research program
project - Purification of plasma antihemophilic factor
(human)
POlHL-06350-17 0015 Hemostasis research program
project • Genetics (human)
P01HL0635017 0018 Hemostasis research program
project - Varients of factors IX (human, cattle)
ROlHL-09163-13 Control mechanisms in hemostasis
(human)
ROlHL-09902-13 Comparative study of coagulation and
vascular disease (animals)
R01HL-I0582-12 Thrombosis and hemostasls-Analysis,
methods and standards (human, cattle, venom)
POlHL-13108-09 0014 Clinical heart transplantation -
Platelets and coagulation in accelerated graft coronary
atherosclerosis
ROIHL- 136 29-08 Hemorrhagic diseases (human)
P50HL-142 17-08 0055 Specialized center of research in
thrombosis - Coagulation section-Platelet coagulant activity
(human)
P50HL-142 17-08 0058 Specialized center of research in
thrombosis - Mechanisms of induction and inhibition of
platelet reaction (human, pig)
P50HL-14217-08 0062 Specialized center of research in
thrombosis - Coagulation section-Factor VIII and Factor XII
(human, cattle)
P50HL-14230-07 0098 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Molecular properties of factor VIII (cattle,
human, mice)
ROlHL-14595-07
(human, rats)
ROlHL-14697-07 Role of platelet membranes in
hemostasis (human)
ROlHL-15230-05 Molecular basis of V Willebrand's disease
and hemophilia (human, cattle)
ROlHL-15474-06 Structure and function of the
antihemophilic factor (human, cattle)
ROlHL-15491-06 Blood coagulation-Platelet-plasma
protein interaction (human)
Primary disorders of platelet function
BIO
" POIHI 15596 05 0008 Coagulation. ribiinolyiK.
hemoslitii ind hepatifii Mruclural tludiei and
froctionalion ol antihemophilic factor (human)
" P0IHM5596 05 0010 Coagulation. Iibrinolyiit.
hemostaiis and hepafitli Von Willtbrand t factor (human)
" POIHI 15596 05 0014 Coagulation, fibrinolysis.
hemostasis and hepatitis Von Wiflebrand factor and
platelet retention in glass bead columns (swine)
•• POIHI 15596 05 0018 Coagulation, fibrinoly.is.
hemostasis and hepatitis fncreased plasma lipids on
blood coagulation and thrombosis (human, animals)
" ROIHI 1561506 Structure function studies of human
factor VIII/vWF
•' POIHI 1638/04 0008 The bkwd vessel and
thrombogenesis Factor VIII m hemostasis (human,
rabbits)
•• POIHL 16411 04 0005 Blood systems in coagulation and
vessel disease Chemical analysis of serum components
associated with coagulation (human, animal)
** POIHL 16411 04 0006 Blood systems in coagulation and
vessel disease Factor VII Immunochemistry and
immunobiology (human, mice)
•* ROIHL 16626 05 Studies of antibodies to antihemophilic
factors (human, rabbits)
** ROIHL 16872 04 Antihemophilic factor (human)
*• ROIHL 1691905 Proteins of blood coagulation (human,
bovine)
** P60HL 17265 04 0002 Community blood resource center
support Research Human factor VIM
P60HL 17265 04 0007 Community blood resource center
support Research Massive transfusion and trauma
(human)
•• POlHL-1 7430-05 0002 Control of coagulation Isolation
of ristocetin-von Willebrand factor (swine)
" POIHL 18576 03 0005 Thrombosis research program
project Molecular basis of von Willebrand's disease and
hemophilia (human, cattle)
P50HL 18828-03 0001 Specialized center of research in
thrombosis Membrane biology and hemostasis (human)
** P50HL-18828-03 0002 Specialized center of research in
thrombosis Endothelial cell biology (human, guinea pig)
ROlHL-18834-04 Metal-dependent complex formation in
blood coagulation (human, cattle)
ROlHL-18852-03 Biochemical studies on the blood
coagulation process (human, cattle)
ROlHL-19267-02 Serial comparative study of Von
Willebrand's disease (human)
ROIHL 1927803 Ristocetin induced platelet aggregation
(human)
** ROlHL-20517-03 Diabetes, somatotropin, factor VIII and
atherosclerosis (human, animal)
** R23HL-21208-02 Structure-function relationships of human
factor VIII
** ROlHL-2 13 79-01
protein (human)
ROlHL-21403-02 Blood clotting kinetics studied by
radioimmunoassay (human)
ROlHL-21644-01 Fibronectin and related glycoproteins
(human, rodents)
•* R23HL-21730-01 vWagll-A new vWD deficient antigen
(human)
ROlHL-22266-01 Production of proteases by lung cells in
culture (human, rodents, rabbits, sheep)
** ROlHL-22355-01 Purification, structure and function of
factor VIII (human)
ROlHL-22471-01 Biochemistry of prothrombin quick
(human)
ROlHL-22875-01 Crotalase-Chemistry, physiology, clinical
potential (rats, rabbits)
ROlHL-22980-01 Kinetic and mechanistic studies of blood
coagulation (human, cattle)
BLOOD COAGULATION, FACTOR IX
SEE ALSO BLOOD COAGULATIOff DISORDERS, CHRISTMAS
DISEASE
ROlHL-02254-23 Blood coagulation and hemorrhagic
disease (human, animals)
ROlHL-03424-21 Formation and properties of prothrombin
derivatives (human, animals)
** POlHL-06350-17 0018 Hemostasis research program
project - Varients of factors IX (human, cattle)
ROlHL-10582-12 Thrombosis and hemostasis-Analysis,
methods and standards (human, cattle, venom)
P50HL-14147-08 0017 Specialized center of research in
thrombosis - Core coagulation laboratory (human)
ROIHL- 15230-05 Molecular basis of V Willebrand's disease
and hemophilia (human, cattle)
POlHL-15596-05 0016 Coagulation, fibrinolysis,
hemostasis and hepatitis ■ Hepatitis-B antigen in whole
blood, plasma and plasma fractions (human, monkeys)
POlHL-15596-05 0017 Coagulation, fibrinolysis,
hemostasis and hepatitis - Heparin and antithrombin III
ROlHL-15728-06 The carbohydrate of the blood-clotting
glycoproteins (mammals)
POlHL-16387-04 0002 The blood vessel and
thrombogenesis - Hormonal effects on thrombogenesis
(rats, rabbits)
ROlHL-16633-04 Chemistry and biology of factor IX
activator (human, mice, rats)
** ROlHL-16919-05 Proteins of blood coagulation (human,
bovine)
ROlHL-16955-05 Heparin, blood coagulation and lipid
metabolism (human)
Structure of factor Vlll-Von Willebrand
at the specific level.
M Grant has subprajects describing specific research aspeds-
See Appendix for investigator's name and grant number
(contd)
BLO
** P60HL-17265-04 0003 Community blood resource center
support • Research-Human factor IX-Role in intrinsic
clotting (also baboons, dogs)
•* ROlHL-17752-03 Purified human clotting factor IX-
Immunologic studies (human)
R01HL18245-03 Transition state analog inhibitors of
thrombin (human, cattle)
** POlHL-18576-03 0007 Thrombosis research program
project - Relationships between coagulability and
thrombosis (human, animals)
ROlHL-18834-04 Metal-dependent complex formation in
blood coagulation (human, cattle)
RaiHL-19131-04 Hypercoagulability and assays for its
protection (human) . „ u ,
** R01HL19331-03 Hirudin isolation and utilization (leeches)
ROlHL-19772-02 Role of warfarin metabolism in
antiuitamin K activity (rats)
R01HL-19982-02 Blood coagulation-Protein-metal lon-lipid
interactions .
ROlHL-20161-02 Role of gamma-carboxyglutamic acid in
blood coagulation (human, cattle)
** ROlHL-2111301 Control mechanisms in coagulation
(cattle) ^ , , ,
** ROlHL-21975-01 Studies on normal and abnormal tactor
IX (human, dogs, cows)
ROlHL-22530-01 Active site studies on blood proteases
ROlHL-22980-01 Kinetic and mechanistic studies of blooa
coagulation (human, cattle)
BLOOD COAGULATION, FACTOR X
ROlHL-03424-21 (formation and properties of prothrombin
derivatives (human, animals)
P01HL0635017 0018 Hemostasis research program
project • Varients of factors IX (human, cattle)
ROlHL-10582-12 Thrombosis and hemostasis-Analysis,
methods and standards (human, cattle, venom)
R01HL1282009 In vitro regulation of prothrombin
activation -
P50HL-14147-08 0003 Specialized center of research in
thrombosis - Surface thrombogenicity and phospholipid
vesicle physical properties ,
P50HL-14147-08 0013 Specialized center of research in
thrombosis - Mathematical models of blood coagulation
kinetics .
P50HL-14147-08 0017 Specialized center of research in
thrombosis ■ Core coagulation laboratory (human)
P50HL-14217-08 0055 Specialized center of research in
thrombosis • Coagulation section-Platelet coagulant activity
R01HTf5230-05 Molecular basis of V Willebrand's disease
and hemophilia (human, cattle)
POlHL-15596-05 0014 Coagulation, fibrinolysis,
hemostasis and hepatitis ■ Von Willebrand factor and
platelet retention in glass bead columns (swine)
P01HH5596-05 0016 Coagulation, fibrinolysis,
hemostasis and hepatitis - Hepatitis-B antigen in whole
blood plasma and plasma fractions (human, monkeys)
POlHL-15596-05 0017 Coagulation, fibrinolysis,
hemostasis and hepatitis ■ Heparin and antithrombin III
" P01HL15596-05 0018 Coagulation, fibrinolysis,
hemostasis and hepatitis - Increased plasma lipids on
blood coagulation and thrombosis (human, animals)
R01HL15728-06 The carbohydrate of the blood-clotting
glycoproteins (mammals)
ROlHL-15887-05 Enzymes of blood coagulation and
fibrinolysis (human)
ROlHL-16150-05 Primary structure of prothrombin (canie,
human) .
•* ROlHL-16238-05 Protein structure in coagulation and
fibrinolysis (human)
POlHL-1641104 0003 Blood systems in coagulation ana
vessel disease - Molecular events involving the late stages
of coagulation (rabbits)
•* ROlHL-16919-05 Proteins of blood coagulation (human,
bovine) , . j , j
R01HL16955-05 Heparin, blood coagulation and lipid
metabolism (human)
POlHL-1743005 0005 Control of coagulation • The
activation of prothrombin (human, cattle, dogs)
P01HL17812-04 0004 Thrombosis and plasma proteins -
Serum-platelet interaction (human)
ROlHL-1824503 Transition state analog inhibitors of
thrombin (human, cattle)
ROlHL-18333-05 Thrombogenesis and hemostatic balance
(rabbits, human)
POlHL-18576-03 0007 Thrombosis research program
project - Relationships between coagulability and
thrombosis (human, animals)
POlHL-18827-02 0007 Platelet vessel wall interactions in
thrombogenesis - Biochemistry and role factor V m
thrombogenesis (human, cattle)
ROlHL-18834-04 Metal-dependent complex formation in
blood coagulation (human, cattle)
ROlHL-18852-03 Biochemical studies on the blood
coagulation process (human, cattle)
ROlHL-19131-04 Hypercoagulability and assays for its
protection (human)
♦• ROlHL-19282-03 Regulation of the activation of human
factor X /I u \
*• ROlHL-19331-03 Hirudin isolation and utilization (leeches)
ROlHL-19772-02 Role of warfarin metabolism in
antivitamin K activity (rats)
56
ROlHL-19982-02 Blood coagulation-Protein-metal ion-lipid
interactions
ROlHL-21113-01 Control mechanisms in coagulation
(""'^' , ^ A ,,
ROlHL-21403-02 Blood clotting kinetics studied by
radioimmunoassay (human)
ROlHL-21543-02 Structure-function relation of blood
clotting proteins (rabbits)
ROlHL-22530-01
(human)
ROlHL-22771-01
(cattle)
' ROlHL-22955-01
ROlHL-2298001
BLO
Genesis of atherosclerotic lesions
Microcrystalline and crystalline fibrinogen
Active site studies on blood proteases
Thrombogenic phospholipid surfaces
inetics of prothrombin activation
Kinetic and mechanistic studies of blood
coagulation (human, cattle)
BLOOD COAGULATION, FACTOR XI
** ROlHL-01661-27 Hemostatic mechanisms (human)
P50HL-14217-08 0055 Specialized center of research in
thrombosis - Coagulation section -Platelet coagulant activity
(human) .
POlHL-164 11-04 0002 Blood systems in coagulation and
vessel disease - Early stages of coagulation and
cardiovascular disease (human, rabbits)
ROIHL 16633-04 Chemistry and biology of factor IX
activator (human, mice, rats)
** ROlHL-16919-05 Proteins of blood coagulation (human,
bovine)
R01HL17402-04 Mechanism of contact activation ot
intrinsic clotting (human)
P01HL18576-03 0007 Thrombosis research program
project ■ Relationships between coagulability and
thrombosis (human, animals)
ROlHL-18650-03 Platelet collagen interaction (human)
R01HL18834-04 Metal-dependent complex formation in
blood coagulation (human, cattle)
** ROlHL-18859-03 Biochemistry of human factor XI (human)
R01HL191 31-04 Hypercoagulability and assays for its
protection (human)
ROlHL-21544-02 Proteins of coagulation and Hageman
factor pathways (human, goats)
ROlHL-21975-01 Studies on normal and abnormal factor
IX (human, dogs, cows)
ROlHL-22530-01 Active site studies on blood proteases
(human) « ui j
ROlHL-22980-01 Kinetic and mechanistic studies of blood
coagulation (human, cattle)
BLOOD COAGULATION, FIBRIN
ROlHL-01601-30 Blood coagulation and hemorrhagic
disease (horseshoe crabs)
ROlHL-01662-25 Equilibria in the fibrinogenfibrin
conversion (human, cattle)
ROlHL-022 12-23 Coagulation of blood (human)
POlHL-0635017 0020 Hemostasis research program
project - Structure and function of coagulant venom
proteases .
** POlHL-06835-17 0028 Cardiovascular disease - Muoies
in thrombosis-fibrinogen in fibrin transport (human)
R01HL07379-13 Structure and function of fibrinogen
(human) « i
R01HL10582-12 Thrombosis and hemostasis-Analysis.
methods and standards (human, cattle, venom)
ROlHL-1 1822-10 Biophysical studies of macromolecular
interactions (microorganism, human)
ROlHL-13198-21 Blood coagulation-Physico-chemical
properties (human, cattle)
R01HL-13596-07 Clearance of plasma proteins trom
alveoli , . .
P50HL-14147-08 0006 Specialized center of research in
thrombosis • Clearance mechanisms of coagulation
moieties (human, rabbits, rodents)
P50HL-14187-07 0008 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses - Pulmonary
thromboembolism (dogs, human)
P50HL-14217-08 0054 Specialized center of research in
thrombosis - Coagulation section -Platelet aggregation
(human, pig. rabbit, dog)
P50HL-14236-05 0003 Prevention of premature
arteriosclerosis - Intravascular clotting in patients with
hyperlipidemia .
** ROlHL-15226-06 Interaction of blood cells with fibrinogen
and fibrin (human, animals)
*• POIHL- 154 86-06 0001 Studies on thrombosis • Studies on
chemistry of fibrinogen (human, dogs)
POIHL- 154 86-06 0002 Studies on thrombosis -
Characterization of antisera to fibrinopeptide B (human,
rabbits)
** POlHL-15596-05 0001 Coagulation, fibrinolysis,
hemostasis and hepatitis ■ Defibrination (human)
" POlHL-15596-05 0002 Coagulation, fibrinolysis,
hemostasis and hepatitis ■ Radioimmunoassay of
fibrinogen and fibrin derivatives (human)
•* R01HL16361-03 Fibrin complexes in intermediary
coagulation (human, rabbits)
POlHL-16411-04 0002 Blood systems in coagulation and
vessel disease - Early stages of coagulation and
cardiovascular disease (human, rabbits)
POlHL-174 19-04 0003 Studies on mechanisms of
hemostasis • Characterization of fibrinogen (human)
ROlHL-17964-04 The alternate pathway for fibrinolysis
(human)
ROlHL-18473-04
(human, mules)
♦ ROlHL-18533-03
(cattle, bacteria)
* POlHL-18576-03 0002 Thrombosis research program
project ■ Molecular basis of fibrin formation (human, cattle,
lamprey)
ROlHL-18644-03 Prosthesis for aortocoronary bypass
(dogs, baboons)
■* ROlHL-18672-03 Dynamic studies of clot structure
formation (human)
•* ROlHL-18935-03 Platelets, fibrinogen, soluble fibnn
interaction (human)
'* ROlHL-19105-02 Detection and adherence ot fibrin
monomer complexes (human)
R01HL19767-01 Pathochemistry of fibrinogen (humans)
** ROlHL-20014-02 Radioimmunoassay of hyper and
hypocoagulable states (rabbits)
" ROlHL-2010602 Coupling of platelet contractile proteins
to fibrin (human)
** ROlHL-20218-02 Fibrinogen catabolism and intravascular
coagulation (human)
** ROlHL-20319-02 Assembly, structure and interactions ot
fibrin (human)
ROlHL-21001-01 Protein and thrombus deposition on
vascular grafts .
P50HL-2 1006-02 0006 Specialized center of research in
arteriosclerosis - Intravascular coagulation and thrombosis
in hyperlipidemia (human)
ROlHL-21548-01 Pathogenesis of pulmonary
thromboembolic disease (human, mammals)
ROlHL-2 1644-01 Fibronectin and related glycoproteins
(human, rodents)
ROlHL-22505-01 Molecular pathology of fibrinogen and
factor Xlll (human, animals)
ROlHL-22955-01 inetics of prothrombin activation
BLOOD COAGULATION, FIBRIN STABILIZING
FACTOR
** ROlHL-02212-23 Coagulation of blood (human)
POlHL-06835-17 0027 Cardiovascular disease - Studies
in thrombosis-cross-linking of fibrinogen (human)
ROlHL-07379-13 Structure and function of fibrinogen
(human)
ROlHL-10582-12 Thrombosis and hemostasis-Analysis.
methods and standards (human, cattle, venom)
P50HL-14217-08 0048 Specialized center of research in
thrombosis Fibrinolysis section-Structural studies (human,
** ROlHL-16346-09 Enzyme assay for blood clotting (human)
ROlHL-16361-03 Fibrin complexes in intermediary
coagulation (human, rabbits)
R01HL-1776903 New methods of studying blood
coagulation kinetics
ROlHL-20106-02 Coupling of platelet contractile proteins
to fibrin (human)
ROlHL-20319-02 Assembly, structure and interactions ot
fibrin (human)
" ROlHL-21 139-02 Molecular biology of factor Xlll (human)
ROlHL-21644-01 Fibronectin and related glycoproteins
(human, rodents)
** ROlHL-22505-01 Molecular pathology of fibrinogen and
factor Xlll (human, animals)
BLOOD COAGULATION, FIBRINOGEN
SEE ALSO BLOOD COAGULATION, CRYOFIBRINOGEN
SEE ALSO BLOOD COAGUUTION DISORDERS.
AFIBRINOGENEMIA
ROlHL-01601-30 Blood coagulation and hemorrhagic
disease (horseshoe crabs)
ROlHL-01662-25 Equilibria in the fibrinogenfibrin
conversion (human, cattle)
** ROlHL-02262-23 Mechanisms regulating plasma proteins
and solutes (human, dogs)
ROlHL-03181-21 0025 Hemodynamics as applied to
surgical problems • Vascular stenosis (dogs)
POlHL-06350-17 0020 Hemostasis research program
project - Structure and function of coagulant venom
proteases
** POlHL-06835-17 0027 Cardiovascular disease - Studies
in thrombosis-cross-linking of fibrinogen (human)
** POlHL-06835-17 0028 Cardiovascular disease - Studies
in thrombosis-fibrinogen in fibrin transport (human)
*• ROlHL-07379-13 Structure and function of fibrinogen
(human)
ROlHL-0839915 Platelet injury in infections and allergic
diseases (human)
" POlHL-09011-15 0002 A research and resource program
in blood - Biosynthesis of fibrinogen (dogs)
ROlHL-10608-12 Digoxin-specific antibodies (human)
ROlHL-11822-10 Biophysical studies of macromolecular
interactions (microorganism, human)
ROlHL-13036-08 Coronary thrombosis-Effects on
myocardium and in vivo detection (dogs, monkeys)
ROlHL-13198-21 Blood coagulation-Physico-chemical
properties (human, cattle)
ROlHL-13596-07 Clearance of plasma proteins from
alveoli .
•* P50HL-14147-08 0006 Specialized center of research in
thrombosis - Clearance mechanisms of coagulation
moieties (human, rabbits, rodents)
(contd)
•taludes rouline methodok)g, OR covers only general proiects which preclude
••Oriented significantly to above subject.
indexing at the specific level.
M Grant has subpro)ects describing specific research aspects.
See Appendix for investigator's name and grant number.
uo
PSOHl 14147 Oa 0007 Speclalligd ctntor o( resssrch in
thrombosis Ridioactive ti<c«ts in iBCOgnitian ol
inttavisrulai coagulition (human. (lo|i>)
•• P50HL 14? 17 08 0048 SpecialKod cantai ol (oseaich in
thrombosis fibrinolysis saction Stiucliiral studies (human,
animal)
PSOHL 14217 08 0049 Specialirad canter ol research in
thrombosis fibrinolysis section Clinical studies
P50MI 1421708 OOiO Specialiied center ol research in
thrombosis Electron microscopy section (do|sl
PSOHL 14217 08 00S4 Specialiied center ol research in
thrombosis Coagulation section Platelet aggregation
(human, pig, rabbit, dog)
ROIHL 1499207 Mechanism of thrombin action (human)
POIHL 1S19S04 0002 Progrnm project in biological
materials Structural and surlace characteruation
"• ROIHI 1S226 06 Interaction ot blood cells with fibrinogen
and libiin (human, animals)
•* POIHL 1S486 06 0001 Studies on thrombosis Studies on
chemistry ot librinogen (human, dogs)
•• P01HL15486 06 0002 Studies on thrombosis
Characterization ol antisera to librinopeptide B (human,
rabbits)
** POIHL 15486 06 0003 Studies on thrombosis
Mechanism and prevention of librinopeptide B degradation
(human)
*' POIHL 15486 06 0004 Studies on thrombosis
Thrombosis, intravascuair coagulation, platelet aggregation
(dogs)
•* P01HL1548606 0006 Studies on thrombosis Clinical
investigation unit
ROIHL 1559305 Prolonged extracorporeal cardiopulmonary
support (rats sheep, rabbits)
** POIHL 15596-05 0001 Coagulation, fibrinolysis,
hemostasis and hepatitis Defibrination (human)
'* P01HL1559605 0002 Coagulation, fibrinolysis,
hemostasis and hepatitis - Radioimmunoassay of
fibrinogen and fibrin derivatives (human)
** P01HL1559605 0003 Coagulation, fibrinolysis,
hemostasis and hepatitis ■ Plasmin degraded fibrinogen
fractions (human)
P01HL1559605 0016 Coagulation, fibrinolysis,
hemostasis and hepatitis - Hepatitis B antigen in whole
blood, plasma and plasma fractions (human, monkeys)
POlHL-15596-05 0017 Coagulation, fibrinolysis,
hemostasis and hepatitis - Heparin and antithrombin III
P60HL- 1599606 0001 Cincinnati comprehensive sickle
cell center - Coagulation mechanisms in sickle cell disease
(human)
** R01HL16361-03 Fibrin complexes in intermediary
coagulation (human, rabbits)
** P01HL-I641I04 0003 Blood systems in coagulation and
vessel disease - Molecular events involving the late stages
of coagulation (rabbits)
** R01HL1644505 Regulation of plasma protein
biosynthesis (rats, rabbits)
'* ROlHL-16646-05 Pathobiology of thromboembolic disorders
(human)
P60HL17265 04 0003 Community blood resource center
support ■ Research-Human factor IX-Role in intrinsic
clotting (also baboons, dogs)
M POlHL-17419-04 Studies on mechanisms of hemostasis
** POlHL-1741904 0001 Studies on mechanisms of
hemostasis ■ Structure and metabolism of fibrinogen
(human)
** POlHL-1 74 19-04 0003 Studies on mechanisms of
hemostasis - Characterization of fibrinogen (human)
•* POIHL- 174 19-04 0006 Studies on mechanisms of
hemostasis - Effect of hormones, drugs and other agents
on fibrinogen synthesis (chick)
" POIHL- 174 19-04 0007 Studies on mechanisms of
hemostasis - Structural analysis of ordered forms of
fibrinogen (human, cattle)
ROlHL-17503-03 Vascular bubbles in decompression
sickness (minipig, dog, goat)
ROlHL-17623-05 Initial events in thrombus formation on
surfaces (human, rats)
POlHL-17812-04 0007 Thrombosis and plasma proteins -
Blood components-Response to endotoxin (dogs, baboons)
ROlHL-17930-03 Platelet membrane function-Assessment
and application (animals)
ROIHL- 17964-04 The alternate pathway for fibrinolysis
(human)
ROlHL-18533-03 Microcrystalline and crystalline fibrinogen
(cattle, bacteria)
POlHL-18576-03 0002 Thrombosis research program
proiect - Molecular basis of fibrin formation (human, cattle,
lamprey)
POlHL-18576-03 0007 Thrombosis research program
project - Relationships between coagulability and
thrombosis (human, animals)
* ROIHL 18935-03 Platelets, fibrinogen, soluble fibrin
interaction (human)
R01HL-19I05-02 Detection and adherence of fibrin
monomer complexes (human)
ROlHL-19173-03 Analysis of blood trauma from
microporous oxygenators (human, dogs, rabbits)
ROIHL- 194 1 9-03 Cellular interactions with foreign
materials (mammals)
ROlHL-19767-01 Pathochemistry of fibrinogen (humans)
ROlHL-20014-02 Radioimmunoassay of hyper and
hypccoagulable states (rabbits)
57
ROIHI 20079 02 0003 !hromhorosi%l«nl mnlriinl lllood
suilace interaclions (human, cattle)
•• ROlHt 20092 0? Structural and biological propiirtiK% ol
libiinugen (human, rabbits)
RUIHt 2021802 fibrinogen catabolism and intravascular
coagulation (human)
ROIHI 20313 02 Surface-induced thrombosls-Madilicalion
ol albumin variants (human, goat)
ROIHI 20J19 0? Assembly, structure and interactions ol
fibrin (human)
ROIHI 21001 01 Protein and thrombus deposition on
vascular grafts
P50HL 21006 02 0006 Specialized center ol research in
arteriosclerosis Intravascular coagulation and thrombosis
in hyperlipidemia (human)
R01HL2127302 Fibrinogen labeling with radiometals
ROIHL 21548 01 Pathogenesis ol pulmonary
thromboembolic disease (human, mammals)
POIHL 2?163 01 0001 Surface thrombogenesis
Mechanisms and prevention Initial blood protein and
platelet interactions with biomaterials (baboons)
** ROIHL ??505 01 Molecular pathology of fibrinogen and
factor XIII (human, animals)
ROIHL ??87501 Crotalase-Chemistry, physiology, clinical
potential (rats, rabbits)
•* N01HV3?917 08 Materials development and testing
BLOOD COAGULATION, FIBRINOLYSIS
SEE ALSO BLOOD COAGULATION, PUSMIN
** R01HL01601 30 Blood coagulation and hemorrhagic
disease (horseshoe crabs)
ROIHL 01661-27 Hemostatic mechanisms (human)
** R01HL02254-23 Blood coagulation and hemorrhagic
disease (human, animals)
** ROIHL 04366-19 Plasminogen-Activation and structure-
function relations (mammals, birds)
ROlHL-11172-12 Physiology and biochemistry of
fibrinolytic enzymes (human, animals)
ROlHL-13423-08 Structure function studies of plasminogen
and plasmin (human)
ROlHL-13466-08 Pulmonary platelets in shock, trauma
and embolization (dogs, pigs, rats)
P50HL-14147 08 0006 Specialized center of research in
thrombosis - Clearance mechanisms of coagulation
moieties (human, rabbits, rodents)
P50HL-14187-07 0008 Pulmonary SCOR -Chemical
mediators in pulmonary vascular responses - Pulmonary
thromboembolism (dogs, human)
** P50HL-14217-08 0048 Specialized center of research in
thrombosis - Fibrinolysis section-Structural studies (human,
animal)
** P50HL-142 17-08 0049 Specialized center of research in
thrombosis - Fibrinolysis section -Clinical studies
P50HL- 142 17-08 0050 Specialized center of research in
thrombosis - Electron microscopy section (dogs)
P50HL-142 17-08 0063 Specialized center of research in
thrombosis - Special clinical studies laboratory
P60HL-15160-07 0016 Center for sickle cell disease -
Kinin and plasmin system in sickle cell disease (human)
ROIHL 15535-06 Structure and function of human plasmin
M POlHL-15596-05 Coagulation, fibrinolysis, hemostasis and
hepatitis
POlHL-15596-05 0002 Coagulation, fibrinolysis,
hemostasis and hepatitis - Radioimmunoassay of
fibrinogen and fibrin derivatives (human)
'* ROlHL-15690-07 Hydrolytic enzymes of blood in health
and disease (human, animals)
ROlHL-15817-06 Plasminogen activators from tissues
(human, pig, cattle)
** ROlHL-15887-05 Enzymes of blood coagulation and
fibrinolysis (human)
** ROlHL-16238-05 Protein structure in coagulation and
fibrinolysis (human)
POlHL-164 11-04 0003 Blood systems m coagulation and
vessel disease - Molecular events involving the late stages
of coagulation (rabbits)
ROlHL-16582-05 Artificial lungs (dogs)
R0IHL-I6642-05 Biochemistry and pathophysiology of
plasma kallikrein (human, animals)
** POIHL 17812-04 0002 Thrombosis and plasma proteins ■
Activators of fibrinolysis-Synthesis and degradation
(human, cattle)
** ROlHL-17964-04 The alternate pathway for fibrinolysis
(human)
" POlHL-18576-03 0012 Thrombosis research program
project - Synthetic anticoagulant and thrombolytic agents
(dogs)
ROlHL-186 18-04 Purification and function of human HMW
kininogen
** ROlHL-186 72-03 Dynamic studies of clot structure
formation (human)
ROlHL-18738-02 Prevention of postoperative venous
thrombi (human, cattle)
ROlHL-188 15-03 Surgical vascular disorders (human,
dogs)
POlHL-18827-02 0007 Platelet vessel wall interactions in
thrombogenesis - Biochemistry and role factor V in
thrombogenesis (human, cattle)
ROlHL-19131-04 Hypercoagulability and assays for its
protection (human)
ROlHL-19287-03 The antihypertensive function of the
renal medulla (human, rats, rabbits)
ROIHI 20014 02 Radioimmunoaixy ol hypai and
hypocoigulable ttitei (rtbbitt)
KOI HI 20846 0? Purilicitlon ol bovine pltiniino|tn
proactivator
ROIHL ?l4r>0 0? Lipoprat«in\, hemotliiii and
atheroscloroMt (human, rabbil-.)
** ROlHt 2154002 Sptcilic inhibitori ol coagulalion and
librinolyMS (rait, Mbhil-,. dogs)
ROIHI 21544 0? fiu\cin\ ol coagulation and Hageman
laclor pathways (human, goats)
ROIHL ? 1548 01 Pathogenesis ol pulmonary
thromboembolic disease (human, mammals)
" ROIHL 22289 01 Lndolhelial cell mediated fibrinolysii
(rabbits)
ROIHL 22996 01 Venom proteases Action on plaimi
protease inhibitors (human)
NOIHV 22917 11 Lipid research clinic (human)
BLOOD COAGULATION, FIBRINOLYTIC AGENTS
SfE ALSO BIOOO COAGIJU^TION, LYSOKINASf
SEE ALSO BIOOD COAGUUTIOf*, PIASMIN
SEE ALSO BLOOD COAGUUIION, UROKINASE
SEE ALSO IMMUNOLOGY, ANTIGENS BACTERIAL,
STREPTOKINASE
R01HL04366 19 Plasminogen- Activation and structure
function relations (mammals, birds)
ROIHL 13036-08 Coronary thrombosis Effects on
myocardium and in vivo detection (dogs, monkeys)
ROIHL 1375408 Postoperative thromboembolism in
surgical patients (human)
P50HL 1421708 0049 Specialized center of research in
thrombosis - Fibrinolysis section- Clinical studies
R01HL-I5593 05 Prolonged extracorporeal cardiopulmonary
support (rats, sheep, rabbits)
ROlHL-18672 03 Dynamic studies of clot structure
formation (human)
ROIHL 21544 02 Proteins of coagulation and Hageman
factor pathways (human, goats)
ROIHL 22227-01 A new source of hyaluronidase and
anticoagulants (leeches)
BLOOD COAGULATION, HAGEMAN FACTOR
ROIHL 01661 27 Hemostatic mechanisms (human)
POlHL-06350 17 0015 Hemostasis research program
project - Genetics (human)
P50HL-14217-08 0055 Specialized center of research in
thrombosis - Coagulation section-Platelet coagulant activity
(human)
** P50HL-14217-08 0062 Specialized center of research in
thrombosis - Coagulation section -Factor VIII and Factor XII
(human, cattle)
P60HL-15160-07 0016 Center for sickle cell disease
Kinin and plasmin system in sickle cell disease (human)
POlHL-15195-04 0002 Program project in biological
materials - Structural and surface characterization
POlHL-15596-05 0014 Coagulation, fibrinolysis,
hemostasis and hepatitis - Von Willebrand factor and
platelet retention in glass bead columns (swine)
** ROlHL-15690-07 Hydrolytic enzymes of blood in health
and disease (human, animals)
ROlHL-16238-05 Protein structure in coagulation and
fibrinolysis (human)
** POlHL-16411-04 0002 Blood systems in coagulation and
vessel disease - Early stages of coagulation and
cardiovascular disease (human, rabbits)
" POlHL-16411-04 0005 Blood systems in coagulation and
vessel disease - Chemical analysis of serum components
associated with coagulation (human, animal)
ROlHL-16642-05 Biochemistry and pathophysiology of
plasma kallikrein (human, animals)
** ROlHL-16919-05 Proteins of blood coagulation (human,
bovine)
ROlHL-17402-04 Mechanism of contact activation of
intrinsic clotting (human)
R01HL-I8618-04 Purification and function of human HMW
kininogen
M POlHL-18827-02 Platelet vessel wall interactions in
thrombogenesis
** POlHL-18827-02 0002 Platelet vessel wall interactions in
thrombogenesis - Interactions of vessel wall
macromolecules with factor XII (human, rats)
P50HL-18828-03 0006 Specialized center of research in
thrombosis - Etiology and pathogenesis of atherosclerosis
(rabbit, monkey, rat, human)
ROlHL-19131-04 Hypercoagulability and assays for its
protection (human)
P50HL-19157-02 0008 Studies in cystic fibrosis and
bronchiolitis - Serum proteins in cystic fibrosis (human)
ROlHL-20846-02 Purification of bovine plasminogen
proactivator
** ROlHL-21544-02 Proteins of coagulation and Hageman
factor pathways (human, goats)
ROlHL-22530-01 Active site studies on blood proteases
(human)
BLOOD COAGULATION, HEMOSTATICS
ROlHL-10582-12 Thrombosis and hemostasis-Analysis.
methods and standards (human, cattle, venom)
ROlHL-13629-08 Hemorrhagic diseases (human)
ROlHL-15615-06 Structure-function studies of human
factor VIII/vWF
ROlHL-17769-03 New methods of studying blood
coagulation kinetics
•Excludes routine methodotogy OR covers only general projects which preclude indexing
'Onented significantly to above subject
at the specific level.
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigators name and grant number.
(contd)
BLO
*• R01HL1824904 Isolation and identification of platelet
membrane (human)
** ROlHL-18333-05 Thrombogenesis and hemostatic balance
(rabbits, human)
ROlHL-19278-03 Ristocetin induced platelet aggregation
(human)
BLOOD COAGULATION, HEPARIN CO-FACTOR
P60HLU230-07 0098 A/S SCOR-Lipids, atherosclerosis
and thrombosis ■ Molecular properties of factor VIII (cattle,
human, mice)
ROlHL-1691905 Proteins of blood coagulation (human,
bovine)
BLOOD COAGULATION, HIRUDEN
•* R01HL16238-05 Protein structure in coagulation and
fibrinolysis (human)
** ROIHL 1933103 Hirudin isolation and utilization (leeches)
R01HL20079-02 0003 Thromboresistant material - Blood
surface interactions (human, cattle)
BLOOD COAGULATION, LYSOKINASE
SEE ALSO IMMUNOLOGY, ANTIGENS BACTERIAL,
STREPTOKINASE
POlHL-16411-04 0002 Blood systems in coagulation and
vessel disease • Early stages of coagulation and
cardiovascular disease (human, rabbits)
M POlHL-18827-02 Platelet vessel wall interactions in
thrombogenesis
POlHL-18827-02 0003 Platelet vessel wall interactions in
thrombogenesis ■ Tumor cell and platelets in
thrombogenesis and metastasis (human, animals)
R23HL-2 11 89-01 Regulation of pulmonary endothelial cell
activities (human, cattle)
ROlHL-21548-01 Pathogenesis of pulmonary
thromboembolic disease (human, mammals)
ROlHL-22266-01 Production of proteases by lung cells in
culture (human, rodents, rabbits, sheep)
R01HL-22289-01 Endothelial cell mediated fibrinolysis
(rabbits)
** ROlHL-22939-01 Human kinin and fibrinolytic systems
and renal disease (human)
BLOOD COAGULATION, PLASMIN
SEE ALSO BLOOD COAGULATION, FIBRINOLYTIC AGENTS
ROlHL-04366-19 Plasminogen -Activation and structure-
function relations (mammals, birds)
POlHL-06350-17 0020 Hemostasis research program
project • Structure and function of coagulant venom
proteases
ROlHL-10582-12 Thrombosis and hemostasis-Analysis,
methods and standards (human, cattle, venom)
** R01HL11172-12 Physiology and biochemistry of
fibrinolytic enzymes (human, animals)
** ROlHL-13423-08 Structure-function studies of plasminogen
and plasmin (human)
ROlHL-13596-07 Clearance of plasma proteins from
alveoli .
** P50HL-14147-08 0006 Specialized center of research in
thrombosis - Clearance mechanisms of coagulation
moieties (human, rabbits, rodents)
** P60HL1 5160-07 0016 Center for sickle cell disease ■
Kinin and plasmin system in sickle cell disease (human)
POIHLI 5486-06 0001 Studies on thrombosis - Studies on
chemistry of fibrinogen (human, dogs)
POIHL- 15486-06 0003 Studies on thrombosis -
Mechanism and prevention of fibrinopeptide B degradation
(human)
** ROlHL-15535-06 Structure and function of human plasmin
** POlHL-15596-05 0003 Coagulation, fibrinolysis,
hemostasis and hepatitis - Plasmin degraded fibrinogen
fractions (human)
P01HL1559605 0007 Coagulation, fibrinolysis,
hemostasis and hepatitis - Structural studies and
fractionation of urokinase (human)
POlHL-1559605 0019 Coagulation, fibrinolysis,
hemostasis and hepatitis ■ Protamine assay and serine
proteases
R01HL15615-06 Structure function studies of human
factor VIII/vWF
ROlHL-15690-07 Hydrolytic enzymes of blood in healtn
and disease (human, animals)
R01HL1588705 Enzymes of blood coagulation and
fibrinolysis (human)
ROIHL 16361-03 Fibrin complexes in intermediary
coagulation (human, rabbits)
P01HL1641104 0002 Blood systems in coagulation and
vessel disease Early stages of coagulation and
cardiovascular disease (human, rabbits)
POlHL-16411-04 0003 Blood systems in coagulation and
vessel disease ■ Molecular events involving the late stages
of coagulation (rabbits)
R01HL16919-05 Proteins of blood coagulation (human,
bovine)
P01HL17812-04 0001 Thrombosis and plasma proteins ■
Thrombosis and plasma proteins (cattle, guinea pigs)
R01HL18533-03 Microcrystalline and crystalline fibrinogen
(cattle, bacteria)
POlHL-1857603 0005 Thrombosis research program
project - Molecular basis of von Willebrand's disease and
hemophilia (human, cattle)
P01HL18576-03 0012 Thrombosis research program
project • Synthetic anticoagulant and thrombolytic agents
(dogs)
58
ROlHL-18672-03 Dynamic studies of clot structure
formation (human) .
P50HL-1882803 0003 Specialized center of research m
thrombosis - Structure and function of plasma coagulation
inhibitors (human)
R01HL19131-04 Hypercoagulability and assays for its
protection (human)
ROlHL-200 14-02 Radioimmunoassay of hyper and
hypocoagulable states (rabbits)
ROlHL-20319-02 Assembly, structure and interactions of
fibrin (human)
ROlHL-2084602 Purification of bovine plasminogen
proactivator
P50HL-2 1006-02 0006 Specialized center of research in
arteriosclerosis ■ Intravascular coagulation and thrombosis
in hyperlipidemia (human)
ROlHL-2154002 Specific inhibitors of coagulation and
fibrinolysis (rats, rabbits, dogs)
ROlHL-21544-02 Proteins of coagulation and Hageman
factor pathways (human, goats)
ROlHL-22530-01 Active site studies on blood proteases
(human)
ROlHL-22996-01 Venom proteases-Action on plasma
protease inhibitors (human)
BLOOD COAGULATION, PLASMINOGEN
** ROlHL-04366-19 Plasminogen-Activation and structure-
function relations (mammals, birds)
R01HL10582-12 Thrombosis and hemostasis-Analysis,
methods and standards (human, cattle, venom)
** R01HL11172-12 Physiology and biochemistry of
fibrinolytic enzymes (human, animals)
ROIHLI 3 160-08 Human thrombin (also cattle)
** ROlHL-13423-08 Structure-function studies of plasminogen
and plasmin (human)
R01HL13466-08 Pulmonary platelets in shock, trauma
and embolization (dogs, pigs, rats)
R01HL13596-07 Clearance of plasma proteins from
alveoli .
P50HL141 47-08 0006 Specialized center of research in
thrombosis ■ Clearance mechanisms of coagulation
moieties (human, rabbits, rodents)
** ROlHL-15535-06 Structure and function of human plasmin
** POlHL-15596-05 0007 Coagulation, fibrinolysis,
hemostasis and hepatitis - Structural studies and
fractionation of urokinase (human)
" POlHL-15596-05 0019 Coagulation, fibrinolysis,
hemostasis and hepatitis - Protamine assay and serine
proteases
** ROlHL-15817-06 Plasminogen activators from tissues
(human, pig, cattle)
ROlHL-16150-05 Primary structure of prothrombin (came,
human) .
** R01HL16238-05 Protein structure in coagulation and
fibrinolysis (human)
** P01HL1781204 0001 Thrombosis and plasma proteins
Thrombosis and plasma proteins (cattle, guinea pigs)
** POIHL 17812-04 0002 Thrombosis and plasma proteins -
Activators of fibrinolysis -Synthesis and degradation
(human, cattle)
** R01HL1796404 The alternate pathway for fibrinolysis
(human) .
P50HL-18828-03 0003 Specialized center of research in
thrombosis - Structure and function of plasma coagulation
inhibitors (human)
** ROlHL-20846-02 Purification of bovine plasminogen
proactivator .
** ROlHL-22266-01 Production of proteases by lung cells in
culture (human, rodents, rabbits, sheep)
ROlHL-22289-01 Endothelial cell mediated fibrinolysis
(rabbits)
ROlHL-22530-01 Active site studies on blood proteases
(human)
BLOOD COAGULATION, PLATELET FACTOR III
P50HL-142 17-08 0055 Specialized center of research in
thrombosis ■ Coagulation section -Platelet coagulant activity
(human) , , .
*♦ POlHL-15486-06 0005 Studies on thrombosis - Isolation
and characterization of PF4 antigens (rabbits)
P60HL-15996-06 0001 Cincinnati comprehensive sickle
cell center - Coagulation mechanisms in sickle cell disease
(human)
POlHL-1781204 0004 Thrombosis and plasma proteins -
Serum-platelet interaction (human)
POlHL-18576-03 0001 Thrombosis research program
project ■ Platelet damage from physical forces and
artificial surfaces (human)
** ROlHL-203 17-02 Procoagulant lipoproteins -Biochemistry
and bioactivity (goats, rabbits)
ROlHL-20411-03 Platelet fatty acid metabolism in
diabetes (rat, rabbit, guinea pig)
BLOOD COAGULATION, PROTHROMBIN
SEE ALSO BLOOD COAGULATION DISORDERS,
HYPOPROTHROMBINEMIAS
R01HL01601-30 Blood coagulation and hemorrhagic
disease (horseshoe crabs)
** R01HL03424-21 Formation and properties of prothrombin
derivatives (human, animals)
P01HL0635017 0018 Hemostasis research program
project - Varients of factors IX (human, cattle)
BLO
R01HL09163-13 Control mechanisms in hemostasis
(human)
POlHL-1141411 0033 Thrombosis and atherosclerosis
program ■ Human coumarininduced prothrombin
R01HL12820-09 In vitro regulation of prothrombin
activation
ROlHL-13160-08 Human thrombin (also cattle)
R01HL13198-21 Blood coagulation -Physico-chemical
properties (human, cattle)
P50HL-14147-08 0003 Specialized center of research in
thrombosis ■ Surface thrombogenicity and phospholipid
vesicle physical properties
P50HL-14147-08 0013 Specialized center of research in
thrombosis - Mathematical models of blood coagulation
kinetics , . .
P50HL-14147-08 0014 Specialized center of research in
thrombosis Theoretical models for electrostatic effects in
blood clot formation
ROlHL-14847-07 Mechanism of action of vitamin K and
anticoagulants (rats)
POlHL-15596-05 0016 Coagulation, fibrinolysis,
hemostasis and hepatitis - Hepatitis-B antigen in whole
blood plasma and plasma fractions (human, monkeys)
POlHL-15596-05 0017 Coagulation, fibrinolysis,
hemostasis and hepatitis - Heparin and antithrombin III
* POlHL-15596-05 0018 Coagulation, fibrinolysis,
hemostasis and hepatitis • Increased plasma lipids on
blood coagulation and thrombosis (human, animals)
'* R01HL1561905 Regulation of prothrombin synthesis in
cultured cells (rats)
■• ROlHL-15728-06 The carbohydrate of the blood-clotting
glycoproteins (mammals)
ROlHL-15887-05 Enzymes of blood coagulation and
fibrinolysis (human)
ROlHL-15958-06 X-ray diffraction analysis of thrombin
and neurotoxin
•• R01HL16150-05 Primary structure of prothrombin (cattle,
human)
" ROlHL-1623805 Protein structure in coagulation and
fibrinolysis (human)
ROlHL-1663304 Chemistry and biology of factor IX
activator (human, mice, rats)
R01HL16919-05 Proteins of blood coagulation (human,
bovine) .
•* POlHL-17430-05 0005 Control of coagulation - The
activation of prothrombin (human, cattle, dogs)
** POlHL-17430-05 0006 Control of coagulation • Activation
fragments of prothrombin in vitro and in vivo (human,
dogs, cattle) .
** POlHL-17812-04 0004 Thrombosis and plasma proteins -
Serum-platelet interaction (human)
ROlHL-18245-03 Transition state analog inhibitors of
thrombin (human, cattle)
ROlHL-18435-03 Properties of thrombin and Ac-globulin
(human, animals)
P01HL-1857"03 0007 Thrombosis research program
project ■ i.elationships between coagulability and
thrombosis (human, animals)
ROIHL 18834-04 Metal-dependent complex formation in
blood coagulation (human, cattle)
ROlHL-18852-03 Biochemical studies on the blood
coagulation process (human, cattle)
R01HL19131-04 Hypercoagulability and assays for its
protection (human)
ROlHL-19282-03 Regulation of the activation of human
factor X .t .
** ROlHL-19322-03 Role of pituitary hormones in the action
of vitamin K (rats)
R01HL1977202 Role of warfarin metabolism in
antivitamin K activity (rats)
ROlHL-19982-02 Blood coagulation-Protein-metal lon-hpid
interactions
** ROlHL-2016102 Role of gamma-carboxyglutamic acid in
blood coagulation (human, cattle)
** ROlHL-20577-03 The mechanism of action of vitamin K
ROlHL-21113-01 Control mechanisms in coagulation
** ROlHL-2140302 Blood clotting kinetics studied by
radioimmunoassay (human)
** ROlHL-21431-02 Factor II antigen and coagulant activity
(human, animals)
** R01HL-21543-02 Structure-function relation of blood
clotting proteins (rabbits)
** ROlHL-22471-01 Biochemistry of prothrombin quick
(human)
ROlHL-22530-01 Active site studies on blood proteases
(human)
** ROlHL-2277101 Thrombogenic phospholipid surfaces
(cattle) , . .
R23HL-22799-01 Interaction of the complement ana
coagulation systems (monkeys)
** ROlHL-22955-01 inetics of prothrombin activation
BLOOD COAGULATION, THROMBIN
ROlHL-01601-30 Blood coagulation and hemorrhagic
disease (horseshoe crabs)
ROlHL-01662-25 Equilibria in the fibrinogen-fibrin
conversion (human, cattle)
** R01HL02212-23 Coagulation of blood (human)
" R01HL02262-23 Mechanisms regulating plasma proteins
and solutes (human, dogs)
** ROlHL-03424-21 Formation and properties of prothrombin
derivatives (human, animals)
(contd)
•Excludes routine methodotogy OR covers only general projects which preclude
"Oriented significantly to above subject.
indexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
BIO
P0IH1063I4 17 0054 Immunologic mechanljms in
Cirdlov«»cul«i diiMs* Phyjiology ol coll communlc^llon^
(nilct. Itogs. |uin*i pigs)
flOlHl'09163 13 Control mechinlsms In hemoslisii
(humin)
ROIHI 09/39 13 Biophyjiol studits o( pioleins (humin)
ROIHI 10b82 12 Thrombosis and h«mo$l«sis Analysis,
mtthods and standaids (human, cattlt. venom)
ROIHL 11963 10 Biochomlsti> ot blood vtssel loimjtion
and disease (swine)
ROIHL 1282009 In witco regulation o( prottirombin
activation
** ROIHL 1316008 Human thrombin (also cattle)
ROIHL 13198 21 Blood coagulation Physico-chemical
properties (human, cattle)
POIHL 13262 O; 0022 Arlerial wall in atherosclerosis
Mechanisms ot platelet prostaglanoin toimation
ROIHL 1402006 Characteruation ol myosin Irom blood
platelets (rabbit)
P50HI 14147 08 0001 Specialised center ot research in
thrombosis Role of aspirin, other anti platelet agents in
platelet function (tat. human)
P50HL 14147 08 0012 Specialued center ol research in
thrombosis Tissue culture study of arterial cells (human,
hamster)
P50HL 1414708 0013 Specialiied center of research in
thrombosis • Mathematical models of blood coagulation
kinetics
P50H11423007 0095 A/S SCOR Lipids, atherosclerosis
and thrombosis Blood platelet adherence to endothelial
smooth muscle cells, fibroblast (human)
P50HL 14230 07 0096 VS SCORLipids. atherosclerosis
and thrombosis Ultrastructural studies of endothelial cells
(human)
P50HL- 1423007 0098 A/S SCOR-Lipids. atherosclerosis
and thrombosis - Molecular properties of factor VIII (cattle,
human, mice)
ROlHL-14697-07 Role of platelet membranes in
hemostasis (human)
ROIHL 14992-07 Mechanism of thrombin action (human)
ROlHL-15230-05 Molecular basis of V Willebrand's disease
and hemophilia (human, cattle)
ROIHL- 15335-06 The nature of the collagen-platelet
interaction (animals)
POlHL-15486-06 0003 Studies on thrombosis -
Mechanism and prevention of fibrinopeptide B degradation
(human)
POlHL-15596-05 0017 Coagulation, fibrinolysis.
hemostasis and hepatitis - Heparin and antifhrombin III
R01HL-I5616-04 Platelet membrane proteins in
aggregation (human)
ROlHL-15887-05 Enzymes of blood coagulation and
fibrinolysis (human)
'* ROlHL-15958-06 X-ray diffraction analysis of thrombin
and neurotoxin
ROlHL-16150-05 Primary structure of prothrombin (cattle,
human)
ROlHL-16238-05 Protein structure in coagulation and
fibrinolysis (human)
ROIHL- 16346-09 Enzyme assay for blood clotting (human)
R01HL-I6355-05 Reactions of thrombin and collagen with
platelets (human)
ROlHL-16361-03 Fibrin complexes in intermediary
coagulation (human, rabbits)
ROlHL-16633-04 Chemistry and biology of factor IX
activator (human, mice, rats)
ROlHL-16634-13 Regulation of metabolism in fibroblasts
and platelets (human, rabbits, sheep)
* ROlHL-16720-02 Platelet aggregation (human)
ROlHL-16872-04 Antihemophilic factor (human)
ROlHL-16919-05 Proteins of blood coagulation (human,
bovine)
R01HL-16955-05 Heparin, blood coagulation and lipid
metabolism (human)
POlHL-1743005 0006 Control of coagulation - Activation
fragments of prothrombin in vitro and in vivo (human,
dogs, cattle)
ROlHL-1 751304 Role of PF-4 in detecting and promoting
thrombosis (human, primates)
POIHLI 7812-04 0004 Thrombosis and plasma proteins -
Seromplatelet interaction (human)
POlHL-17812-04 0005 Thrombosis and plasma proteins ■
In vitro systems of normal platelets, white cells, sera
(human)
ROIHL- 17930-03 Platelet membrane function-Assessment
and application (animals)
ROlHL-18245-03 Transition state analog inhibitors of
thrombin (human, cattle)
R01HL-I8435-03 Properties of thrombin and Ac-globulin
(human, animals)
POIHL-18576-03 0001 Thrombosis research program
project - Platelet damage from physical forces and
artificial surfaces (human)
POIHL-18576-03 0005 Thrombosis research program
project ■ Molecular basis of von Willebrands disease and
hemophilia (human, cattle)
POlHL-18576-03 0011 Thrombosis research program
project ■ Proteolysis and platelet function (human, cattle
rabbits)
POlHL-1857603 0012 Thrombosis research program
project - Synthetic anticoagulant and thrombolytic agents
(dogs)
I*
Point 18827 02 000/ Platelet vo^el wall interactions in
thiombogenesis Biochemistry and role factor V in
thfombogenesls (human, cattle)
PbOHl 18H28 03 0003 Specialized center ot research In
thrombosis Structure and function of plasma coagulation
inhibitors (human)
P50HL 1882803 0004 Specialized center ot research in
thrombosis Membrane changes m platelet physiology Role
ol complement (mice, human)
ROIHL 18834 04 Metal dependent complex formation in
blood coagulation (human, cattle)
ROIHI 18852 03 Biochemical studies on the blood
coagulation process (human, cattle)
ROIHL 18935 03 Platelets, fibrinogen, soluble fibrin
interaction (human)
ROIHL 19282 03 Regulation of the activation ot human
factor X
ROIHL 19331-03 Hirudin isolation and utilization (leeches)
ROIHL- 195 14-03 Proteinase Inhibitor model with clinical
potential
ROIHL 2007902 0003 Thromboresistant material Blood
surface interactions (human, cattle)
ROIHL 205 17 03 Diabetes, somatotropin, factor VIII and
atherosclerosis (human, animal)
ROIHL 20971 10 Membrane glycoproteins ol platelets and
leukocytes (human)
P50HL-21006-02 0006 Specialized center of research in
arteriosclerosis - Intravascular coagulation and thrombosis
in hyperlipidemia (human)
ROIHL 2111301 Control mechanisms in coagulation
(cattle)
R23HI-21208-02 Structure-function relationships of human
factor VIII
ROlHL-21403-02 Blood clotting kinetics studied by
radioimmunoassay (human)
ROlHL-2 1540-02 Specific inhibitors of coagulation and
fibrinolysis (rats, rabbits, dogs)
ROlHL-21548-01 Pathogenesis of pulmonary
thromboembolic disease (human, mammals)
ROlHL-21 769-01 Blood compatible benzamidine containing
polymers
ROlHL-2250201 Role of phosphoinositides in human
platelet secretion
ROlHL-22771-01 Thrombogenic phospholipid surfaces
(cattle)
R23HL-22799-01 Interaction of the complement and
coagulation systems (monkeys)
ROlHL-22875-01 Crotalase-Chemistry. physiology, clinical
potential (rats, rabbits)
ROlHL-22955-01 inetics of prothrombin activation
BLOOD COAGULATION, THROMBOPLASTIN
ROlHL-10582-12 Thrombosis and hemostasis-Analysis.
methods and standards (human, cattle, venom)
ROlHL-1 1686-09 Dynamics of thrombus formation and
dissolution (human, chickens)
ROlHL-13198-21 Blood coagulation -Physico-chemical
properties (human, cattle)
ROlHL-14739-06 The role of leukocytes in thrombotic
disease (human, dogs)
ROlHL-152 15-06 Role of complement in intravascular
coagulation (rabbits, mice)
POlHL-15486-06 0003 Studies on thrombosis -
Mechanism and prevention of fibrinopeptide B degradation
(human)
POlHL-15486-06 0004 Studies on thrombosis -
Thrombosis, intravascuair coagulation, platelet aggregation
(dogs)
POlHL-16411-04 0001 Blood systems in coagulation and
vessel disease - Molecular studies of the role of
complement in blood coagulation (human, rabbits)
POlHL-16411-04 0002 Blood systems in coagulation and
vessel disease - Early stages of coagulation and
cardiovascular disease (human, rabbits)
POlHL-17430-05 0005 Control of coagulation - The
activation of prothrombin (human, cattle, dogs)
POlHL-17430-05 0006 Control of coagulation - Activation
fragments of prothrombin in vitro and in vivo (human,
dogs, cattle)
ROlHL-1 7769-03 New methods of studying blood
coagulation kinetics
POIHL-18576-03 0007 Thrombosis research program
project - Relationships between coagulability and
thrombosis (human, animals)
** POlHL-18576-03 0009 Thrombosis research program
project - Biology of factor VII (human, rabbits, cattle)
ROlHL-203 17-02 Procoagulant lipoproteins-Biochemistry
and bioactivity (goats, rabbits)
ROlHL-22980-01 Kinetic and mechanistic studies of blood
coagulation (human, cattle)
BLOOD COAGULATION, THROMBOPOIESIS
INHIBITORS
ROlHL-022 12-23 Coagulation of blood (human)
ROlHL-10582-12 Thrombosis and hemostasis-Analysis.
methods and standards (human, cattle, venom)
ROlHL-1 1686-09 Dynamics of thrombus formation and
dissolution (human, chickens)
ROlHL-11775-11 Platelet mechanisms in disease (human,
primates)
ROlHL-14637-05 Thrombopoietin-lmmunoassay and
characterization (mice)
ROlHL-14992-07 Mechanism of thrombin action (human)
•bchides routine melhodotogy OR covers only general projects which preclude indexine
Onented significantly to above subject.
BIO
ROIHI 1588/05 Cniymo ot blood lotiulalion and
lihrinolysis (human)
ROIHI 17/69 0] New methods ol studying blood
roagutation kinclics
ROIHI 1/964 04 The sHernate pathway tor fibrinolysis
(human)
ROIHL 18333 05 Thrombogenesis and hemostatic balance
(rabbits, human)
" P50HL 18828 03 0003 Specialized c«nltr ot riMirch in
thrombosis Structure and function ol plasma coagulation
inhibitors (human)
ROlHt 20218 0? Fibrinogen catabolism and intravascular
coagulation (human)
ROIHI 21460 0? lipoproleini. hemostasis and
atherosclerosis (human, rabbits)
ROIHL 21548 01 Pathogenesis of pulmonary
thromboembolic disease (human, mammals)
" NOIHV 5290704 Interactions of platelets with collagent
(human, mammals)
BLOOD COAGULATION, THROMBOPOIESIS
STIMULATING FACTORS
ROIHL 14637 05 Thrombopoietin Immunoassay and
characterization (mice)
ROIHL 15647 06 Hematopoietic studies of cyclic
hematopoiesis (dogs)
BLOOD COAGULATION, THROMBOPOIESIS
STIMULATING FACTORS, THROMBOPOIETIN
ROIHL 01601 30 Blood coagulation and hemorrhagic
disease (horseshoe crabs)
ROIHL 10567 12 Erythropoietin- Immunoassay and
characterization (dogs)
ROIHL 14637-05 Thrombopoietin-lmmunoassay and
characterization (mice)
ROIHL 15647-06 Hematopoietic studies of cyclic
hematopoiesis (dogs)
ROIHL 20826-02 Megakaryocyte proliferation and its
control (mice)
BLOOD COAGULATION, THROMBOSTHENIN
ROIHL 14020-06 Characterization of myosin from blood
platelets (rabbit)
ROlHL-l 7769-03 New methods ol studying blood
coagulation kinetics
ROIHL 2031902 Assembly, structure and interactions of
fibrin (human)
BLOOD COAGULATION, UROKINASE
ROlHL-04366 19 Plasm inogen-Activation and structure-
function relations (mammals, birds)
ROlHL-10582-12 Thrombosis and hemostasis-Analysis.
methods and standards (human, cattle, venom)
R01HL-13423-08 Structure-function studies of plasminogen
and plasmin (human)
P50HL-14217-08 0049 Specialized center of research in
thrombosis - Fibrinolysis section-Clinical studies
P50HL-14217-08 0052 Specialized center of research in
thrombosis - Radioisotope nuclear medicine section
(human, dog)
** POlHL-15596-05 0001 Coagulation, fibrinolysis,
hemostasis and hepatitis - Defibrination (human)
" POlHL-15596-05 0007 Coagulation, fibrinolysis,
hemostasis and hepatitis - Structural studies and
fractionation of urokinase (human)
ROlHL-15817-06 Plasminogen activators from tissues
(human, pig, cattle)
ROlHL-16150-05 Primary structure of prothrombin (cattle,
human)
ROlHL-21540-02 Specific inhibitors of coagulation and
fibrinolysis (rats, rabbits, dogs)
ROlHL-22939-01 Human kinin and fibrinolytic systems
and renal disease (human)
BLOOD COAGULATION DISORDERS
SEE ALSO BLOOD AND RE DISORDERS, HEMORRHAGIC
DISORDERS
SEE ALSO BLOOD PLATELETS DISORDERS
ROlHL-02262 23 Mechanisms regulating plasma proteins
and solutes (human, dogs)
ROlHL-04366-19 Plasminogen-Activation and structure-
function relations (mammals, birds)
** POlHL-06350-17 0015 Hemostasis research program
project - Genetics (human)
ROlHL-09163-13 Control mechanisms in hemostasis
(human)
R01HL09902-13 Comparative study of coagulation and
vascular disease (animals)
ROlHL-11775-11 Platelet mechanisms in disease (human,
primates)
R01HL-I1880-10 Physiology and pathology of blood
platelets (human, dogs)
P50HL-14147-08 0017 Specialized center of research in
thrombosis - Core coagulation laboratory (human)
P50HL-14217-08 0048 Specialized center of research in
thrombosis - Fibrinolysis section -Structural studies (human,
animal)
P50HL-14217-08 0055 Specialized center of research in
thrombosis ■ Coagulation section-Platelet coagulant activity
(human)
ROlHL-15474-06 Structure and function of the
antihemophilic factor (human, cattle)
M POlHL-15596-05 Coagulation, fibrinolysis, hemostasis and
hepatitis
at the specific level.
M Grant has subprojects describing specific research aspects
See Appendix for investigator's name and grant number.
(contd)
BIO
P01HL16411-04 Blood systems in coagulation and vessel
disease
R01HL16445-05 Regulation of plasma protein
biosynthesis (rats, rabbits)
ROlHL-16919-05 Proteins ot blood coagulation (human,
bovine)
P60HL-17265-04 0007 Community blood resource center
support - Research-Masswe transfusion and trauma
(human)
H POlHL-17430-05 Control of coagulation
ROlHL-17973-04 Cultured aortic endothelial cells (human,
cattle, dogs, swine) , „ ,, „
P01HL-18208-04 0001 Center for the study of blood cell
rheology ■ Physiological basis of reversible erythrocyte
shape change (human, firefly)
** ROlHL-18507-03 Clinical studies of Fletcher factor
(human) .
M P01HL1857603 Thrombosis research program proiect
** ROlHL-18672-03 Dynamic studies of clot structure
formation (human)
** R01HL19255-03 Evaluation of diagnostic clinical
hemorrheology (human)
RClHL-19272-03 Studies on the Passovoy factor (human)
ROlHL-19322-03 Role of pituitary hormones in the action
of vitamin K (rats)
** ROlHL-20014-02 Radioimmunoassay of hyper and
hypocoagulable states (rabbits)
** ROlHL-20092-02 Structural and biological properties ot
fibrinogen (human, rabbits)
** ROlHL-21487-01 Molecular characterization of
Glanzmann's thrombasthenia (human)
BLOOD COAGULATION DISORDERS,
AFIBRINOGENEMIA
** POlHL-15486-06 0003 Studies on thrombosis •
Mechanism and prevention of fibrinopeptide B degradation
(human)
M P01HL17419-04 Studies on mechanisms ot hemostasis
BLOOD COAGULATION DISORDERS, CHRISTMAS
DISEASE
SEE ALSO BLOOD COAGUUTION, FACTOR IX
** P60HL-1 7265-04 0003 Community blood resource center
support - Research -Human factor IX -Role in intrinsic
clotting (also baboons, dogs)
ROlHL-17752-03 Purified human clotting factor IX -
Immunologic studies (human)
ROlHL-20161-02 Role of gamma-carboxyglutamic acid in
blood coagulation (human, cattle)
ROlHL-21975-01 Studies on normal and abnormal factor
IX (human, dogs, cows)
BLOOD COAGULATION DISORDERS, FACTOR VII
DEFICIENCY
ROlHL-09902-13 Comparative study of coagulation and
vascular disease (animals)
BLOOD COAGULATION DISORDERS, FACTOR XI
DEFICIENCY
POlHL-06350-17 0018 Hemostasis research program
project - Varients of factors IX (human, cattle)
ROlHL-09902-13 Comparative study of coagulation and
vascular disease (animals)
BLOOD COAGULATION DISORDERS,
HEMOPHILIA
SEE ALSO BLOOD COAGULATION, FACTOR VIII
SEE ALSO BLOOD COAGULATION DISORDERS, CHRlSTfiflAS
DISEASE
SEE ALSO BLOOD COAGUUTION DISORDERS, FACTOR XI
DEFICIENCY
SEE ALSO BLOOD COAGULATION DISORDERS, VON
WILLEBRAND'S DISEASE
NOlHB-53016-05 Cooperative study of factor VIII inhibitors
in patients with hemophilia
** NOlHB-53018-04 Cooperative studies of factor Vlll
inhibitors in patients with hemophilia
" NOlHB-53019-06 Cooperative study of factor Vlll inhibitors
in patients with hemophilia ^ i,i.„,c
" N01HB-53020-04 Cooperative study of factor Vlll inhibitors
in patients with hemophilia . ki.„,.
" NOlHB-53021-05 Cooperative study of factor Vlll inhibitors
in patients with hemophilia
•♦ NOlHB-5302304 Cooperative study of factor Vlll inhibitors
in patients with hemophilia
•• NOlHB-5302404 Cooperative studies of factor Vlll
inhibitors in patients with hemophilia
** NOIHB 53025-05 Cooperative studies of factor Vlll
inhibitors in patients with hemophilia
*• NOlHB-53035-04 Factor Vlll inhibitors in patients with
hemophilia , .
** ROlHL-01648-31 Blood coagulation and hemophilia (dogs,
swine)
ROlHL-01661-27 Hemostatic mechanisms (human)
ROlHL-02254-23 Blood coagulation and hemorrhagic
disease (human, animals)
POlHL-0635017 0005 Hemostasis research program
project Purification of plasma antihemophilic factor
(human)
POlHL-06350-17 0015 Hemostasis research program
project Genetics (human)
R01HL-09163I3 Control mechanisms in hemostasis
(human)
60
ROlHL-09902-13 Comparative study of coagulation and
vascular disease (animals)
ROlHL-1058212 Thrombosis and hemostasis-Analysis,
methods and standards (human, cattle, venom)
ROlHL-13629-08 Hemorrhagic diseases (human)
' R01HL15230-05 Molecular basis of V Willebrand's disease
and hemophilia (human, cattle)
ROlHL-1547406 Structure and function of the
antihemophilic factor (human, cattle)
ROlHL-15491-06 Blood coagulation-Platelet-plasma
protein interaction (human)
* P01HL15596-05 0008 Coagulation, fibrinolysis,
hemostasis and hepatitis ■ Structural studies and
fractionation of antihemophilic factor (human)
* P01HL1641104 0006 Blood systems in coagulation and
vessel disease ■ Factor Vll-lmmunochemistry and
immunobiology (human, mice)
ROlHL-16626-05 Studies of antibodies to antihemophilic
factors (human, rabbits)
■* R01HL1687204 Antihemophilic factor (human)
'* P60HL-17265-04 0001 Community blood resource center
support - Demonstration and evaluation
" P60HL-17265-04 0002 Community blood resource center
support - Research -Human factor Vlll
P60HL-17265-04 0003 Community blood resource center
support - Research -Human factor IX-Role in intrinsic
clotting (also baboons, dogs)
R01HL1746203 Role of glycosphingolipids in platelet
aggregation (rats, human, dogs)
P01HL17812-04 0002 Thrombosis and plasma proteins •
Activators of fibrinolysis-Synthesis and degradation
(human, cattle)
** POlHL-18576-03 0005 Thrombosis research program
project - Molecular basis of von W/illebrand's disease and
hemophilia (human, cattle)
POlHL-18576-03 0007 Thrombosis research program
project Relationships between coagulability and
thrombosis (human, animals)
POlHL-18576-03 0009 Thrombosis research program
project - Biology of factor VII (human, rabbits, cattle)
ROlHL-21379-01 Structure of factor VlllVon Willebrand
protein (human) j , » »
** ROlHL-223 55-01 Purification, structure and function ot
factor Vlll (human)
BLOOD COAGULATION DISORDERS,
HYPOPROTHROMBINEMIAS
** ROlHL-2247101 Biochemistry of prothrombin quick
(human)
BLOOD COAGULATION DISORDERS,
INTRAVASCULAR COAGULATION
DISSEMINATED
SEE ALSO HEMOPROTEINS, HEMOGLOBINOPATHIES, SICKLE
CELL CRISIS
ROlHL-01601-30 Blood coagulation and hemorrhagic
disease (horseshoe crabs)
ROlHL-02254-23 Blood coagulation and hemorrhagic
disease (human, animals)
" POlHL-063 14-17 0047 Immunologic mechanisms in
cardiovascular disease - Role of intravascular coagulation
(human, animals)
** POlHL-06835-17 0027 Cardiovascular disease ■ Studies
in thrombosis-cross-linking of fibrinogen (human)
" POlHL-06835-17 0028 Cardiovascular disease ■ Studies
in thrombosis-fibrinogen in fibrin transport (human)
P01HL10342-13 0028 The integrated function of
respiration and circulation - Mediator release,
hemodynamics and respiratory function in anaphylaxis
(dogs) ■ « 1 ■
ROIHL 10582-12 Thrombosis and hemostasis-flnalysis,
methods and standards (human, cattle, venom)
ROlHL-10608-12 Digoxin-specific antibodies (human)
** POlHL-11310-12 0095 Mechanisms of cardiovascular
disease - Blood and transfusion disorders (human, rats,
monkeys) ^ . j
ROlHL-1 1686-09 Dynamics of thrombus formation and
dissolution (human, chickens)
** ROlHL-1346608 Pulmonary platelets in shock, trauma
and embolization (dogs, pigs, rats)
POlHL-13738-08 0002 Cardiac assist devices and
artificial hearts ■ Total replacement with artificial heart
(calves, sheep, ponies)
" P01HL13738-08 0003 Cardiac assist devices and
artificial hearts - Pathophysiological effects of the artificial
heart (calves)
M P50HL1414708 Specialized center of research in
thrombosis .
P50HL-1414708 0006 Specialized center of research in
thrombosis - Clearance mechanisms of coagulation
moieties (human, rabbits, rodents)
** P50HL-14147-08 0007 Specialized center of research in
thrombosis - Radioactive tracers in recognition of
intravascular coagulation (human, dogs)
" P50HL-14236-05 0003 Prevention of premature
arteriosclerosis - Intravascular clotting in patients with
hyperlipidemia
** ROlHL-1473906 The role of leukocytes m thrombotic
disease (human, dogs)
** ROlHL-15215-06 Role of complement in intravascular
coagulation (rabbits, mice)
M POlHL-15486-06 Studies on thrombosis
M
BLO
POlHL-15486-06 0003 Studies on thrombosis ■
Mechanism and prevention of fibrinopeptide B degradation
(human)
POlHL-15486-06 0004 Studies on thrombosis -
Thrombosis, intravascuair coagulation, platelet aggregation
POIHL- 15486-06 0005 Studies on thrombosis - Isolation
and characterization of PF4 antigens (rabbits)
P01HL1559605 0001 Coagulation, fibrinolysis,
hemostasis and hepatitis ■ Defibrination (human)
POlHL-15596-05 0002 Coagulation, fibrinolysis,
hemostasis and hepatitis - Radioimmunoassay of
fibrinogen and fibrin derivatives (human)
ROlHL-1625405 Pathogenesis of bubble and clot
formation (fish)
ROlHL-16361-03 Fibrin complexes in intermediary
coagulation (human, rabbits)
■ P01HL1641104 0001 Blood systems in coagulation and
vessel disease - Molecular studies of the role of
complement in blood coagulation (human, rabbits)
' POlHL-1641104 0002 Blood systems in coagulation and
vessel disease • Early stages of coagulation and
cardiovascular disease (human, rabbits)
* POlHL-16411-04 0004 Blood systems in coagulation and
vessel disease - Platelets reactions in vascular injury
(human, animals)
R01HL16603-05 Human and experimental renal diseases
(animals) .
R01HL16634-13 Regulation of metabolism in fibroblasts
and platelets (human, rabbits, sheep)
ROlHL-16646-05 Pathobiology of thromboembolic disorders ^
(human)
P01HL17419-04 Studies on mechanisms ot hemostasis
P01HL17419-04 0001 Studies on mechanisms of
hemostasis • Structure and metabolism of fibrinogen
(human)
POlHL-17430-05 0005 Control of coagulation • Ihe
activation of prothrombin (human, cattle, dogs)
POlHL-17430-05 0006 Control of coagulation - Activationl
fragments of prothrombin in vitro and in vivo (human,
dogs, cattle) • , . .v
ROlHL-17752-03 Purified human clotting factor IX -
Immunologic studies (human)
P01HL1857603 0007 Thrombosis research program
project - Relationships between coagulability and
thrombosis (human, animals)
POlHL-1857603 0009 Thrombosis research program
project - Biology of factor VII (human, rabbits, cattle)
P01HL18576-03 0012 Thrombosis research program
project ■ Synthetic anticoagulant and thrombolytic agents
(dogs)
POlHL-18827-02 Platelet vessel wall interactions in
thrombogenesis
■* POlHL-18827-02 0003 Platelet vessel wall interactions in
thrombogenesis - Tumor cell and platelets in
thrombogenesis and metastasis (human, animals)
•* P01HL18827-02 0007 Platelet vessel wall interactions in
thrombogenesis - Biochemistiy and role factor V in
thrombogenesis (human, cattle)
R01HL19105-02 Detection and adherence of fibrin
monomer complexes (human)
ROlHL-19270-03 Effects of erythropoiesis on platelets ana
hemostasis (rats)
** ROlHL-20014-02 Radioimmunoassay of hyper and
hypocoagulable states (rabbits)
** ROlHL-20218-02 Fibrinogen catabolism and intravascular
coagulation (human) .
** P50HL-21006-02 0006 Specialized center of research in
arteriosclerosis - Intravascular coagulation and thrombosis
in hyperlipidemia (human)
R01HL-2U31-02 Factor II antigen and coagulant activity
(human, animals)
ROlHL-2 1460-02 Lipoproteins, hemostasis and
atherosclerosis (human, rabbits)
ROlHL-21548-01 Pathogenesis of pulmonary
thromboembolic disease (human, mammals)
BLOOD COAGULATION DISORDERS, VON
WILLEBRAND'S DISEASE
SEE ALSO BLOOD COAGULATION, FACTOR Vlll
ROlHL-01601-30 Blood coagulation and hemorrhagic
disease (horseshoe crabs)
" ROlHL-01648-31 Blood coagulation and hemophilia (dogs.
swine) .
ROlHL-01661-27 Hemostatic mechanisms (human)
ROlHL-02254 23 Blood coagulation and hemorrhagic
disease (human, animals)
POlHL-0635017 0005 Hemostasis research program
proiect ■ Purification of plasma antihemophilic factor
(human)
P01HL06350-17 0015 Hemostasis research program
project • Genetics (human)
ROlHL-09902-13 Comparative study of coagulation and
vascular disease (animals)
P50HL-14217-08 0055 Specialized center of research in
thrombosis ■ Coagulation section-Platelet coagulant activit
(human) .
P50HL-14217-08 0058 Specialized center of research in
thrombosis - Mechanisms of induction and inhibition of
platelet reaction (human, pig)
ROlHL-14595-07 Primary disorders of platelet function
(human, rats)
(contd)
M
•Excludes routine melhodokigy OR covers only general projects which preclude
••OrieiTted significantly to above subject
indexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigators name and grant number.
■lO
■ R0IHU!>230 0i Moltculii bull Of V Wlllabiand'] dUease
•nd htmophilit (human, cattle)
■ POIHI lbS96 0b 0008 Coatulation, tibiinolysiv
hamostasis and hapatitis Sttuctuial sludias and
Itactionatlon of antihtmophllic tactoi (human)
' POIHL lii96 0b 0010 Coaiulalion, (ibiinolysis.
hamostasis and hepatitis Von Willebiand's lactoi (human)
' POIHI 15596 05 0014 Coatulation. (ibrinolysiv
hamostasis and hepatitis Von Willebiand tacloi and
platelet letention in (lass bead columns (swine)
POIHL 1638; 04 0005 The blood vessel and
thrombogenesis - fluid snilneetini consideiations in
thrombogenesis
POIHL 1638; 04 0008 The blood vessel and
thrombogenesis Factor VIII in hamostasis (human,
rabbits)
POIHL 1641104 0006 Blood systems in coagulation and
vessel disease Factor VII Immunochemistry and
immunobiology (human, mice)
ROIHL 16626 05 Studies ot antibodies to antihemophilic
factors (human, rabbits)
ROIHL 16872 04 Antihemophilic factor (human)
P60HI 1726504 0002 Community blood resource center
support Research Human factor VIII
P01HL1743005 0001 Control of coagulation Porcine
von Willebrand's disease
POIHL 17430 05 0002 Control of coagulation Isolation
of ristocetin- von Willebrand factor (swine)
POIHL 1743005 0008 Control of coagulation ■ Cultures
of von Willebrand endothelial cells (pigs)
ROIHL 1797304 Cultured aortic endothelial cells (human,
cattle, dogs, swine)
POIHL 18576-03 0005 Thrombosis research program
project Molecular basis of von Willebrand's disease and
hemophilia (human, cattle)
P50HL 18828-03 0002 Specialized center of research In
thrombosis ■ Endothelial cell biology (human, guinea pig)
ROlHL-19001-03 Atherosclerosis in bleeder and drug
treated subjects (pigs)
ROlHL-19267-02 Serial comparative study of Von
Willebrand's disease (human)
ROlHL-20924-02 Atherosclerosis and arterial cell functions
(human, rabbits)
R23HL-21208-02
factor VIII
ROlHL-21379-01
protein (human)
R23HL-2 1730-01
(human)
Structure-function relationships of human
Structure of factor Vlll-Von Willebrand
vWagll-A new vWD deficient antigen
granulocytes
NOlHB-62973-05
granulocytes
ROlHL-05351-18
BLOOD COAGULATION TESTS*
SEE ALSO BLOOD COAGUUTION, CLOT RETRACTION
** NOlHB-53020-04 Cooperative study of factor VIII inhibitors
in patients with hemophilia
ROlHL-02212-23 Coagulation of blood (human)
ROlHL-10582-12 Thrombosis and hemostasis-Analysis,
methods and standards (human, cattle, venom)
P50HL-14217-08 0063 Specialized center of research in
thrombosis - Special clinical studies laboratory
** POlHL-15596-05 0019 Coagulation, fibrinolysis,
hamostasis and hepatitis - Protamine assay and serine
proteases
" R01HL-I6346-09 Enzyme assay for blood clotting (human)
P01HL-17430-05 0001 Control of coagulation - Porcine
von Willebrand's disease
POlHL-17430-05 0002 Control of coagulation - Isolation
of ristocetin-von Willebrand factor (swine)
** ROlHL-1 7726-03 Bacterial heparinase in diagnostic
coagulation studies
P01HL18576-03 0013 Thrombosis research program
project ■ Early warning and monitoring test systems in
thrombotic disease (human)
R01HL18618-04 Purification and function of human HII/IW
kininogen
** ROlHL-19105-02 Detection and adherence of fibrin
monomer complexes (human)
ROlHL-21487-01 Molecular characterization of
Glanzmann's thrombasthenia (human)
N01HV-22917-U Lipid research clinic (human)
BLOOD COAGULATION TESTS, PROTHROMBIN
TIME*
ROIHL- 15840-02 Sugar-induced heart lesions and vitamin
K deficiency (birds, mammals subhuman)
BLOOD COAGULATION TESTS, THROMBIC
INDEX*
NOlHV-42961-06 Evaluation of biomaterials in contact
with blood (dogs)
** NOlHV-42969-06 Interactions of natural and chemically
modified biopolymers with blood (dogs)
NO lHV-629 11-04 Vena cava ring tests of biomaterials in
dogs
BLOOD DISORDERS (GENERAL)
SEE BLOOD AND RE DISORDERS. BLOOD DISORDERS
(GENERAL)
BLOOD DISORDERS CONGENITAL (HEREDITARY)
SEE BLOOD AND RE DISORDERS CONGENITAL (HEREDITARY)
BLOOD DONORS
SEE BLOOD TRANSFUSION. BLOOD DONORS
^Excludes routine methodology OR covers onhi general projects which preclude indexing at the specific level
Onented significanthr to above subject.
61
BLOOD FILTERS
Sll moon IHIAIMfNI, BIOOO IIIIFRS
BLOOD FLOW
SF( CAROIOVASCIIIAR fllNCllON. HI OOD (lOW
BLOOD FLOW IMPEDANCE
Sff CARDIOVASCUIAR FUNCTION. BIOOD FlOW IMPfOANCF
BLOOD FLOW MEASUREMENTS
SFF CARDIOVASCUIAR DISORDFRS DIAGNOSIS, BLOOD FLOW
MFASURFMFNIS*
BLOOD Flow OSCILLATORY
SEE CARDIOVASCUUR FUNCTION, BLOOD FLOW
OSCILLATORY
BLOOD FLOWMETERS
SFF CARDIOVASCUIAR DISORDERS DIAGNOSIS, BLOOD FLOW
MFASUREMFNTS*
BLOOD FRACTIONATION
SEE BLOOD AND RE SYSTEM. BLOOD FRACTIONATION
BLOOD GROUP ANTIGENS
SEE BLOOD GROUPS ANTIGENS
BLOOD GROUP INCOMPATIBILITY
SEE ALSO BLOOD GROUPS
SEE ALSO BLOOD TRANSFUSION
ROIHL 10036 13 Biology of red cell antigen-antibody
reaction (human)
BLOOD GROUP INCOMPATIBILITY PERINATAL,
ABO HEMOLYTIC DISEASE NEWBORN
SEE ALSO BLOOD GROUPS. ABO (H) SYSTEM
ROlHL-05351-18 Blood group antigens and antibodies
(human, rabbits, sheep)
BLOOD GROUP ISOANTIBODIES
SEE BLOOO GROUPS ISOANTIBODIES
BLOOD GROUP ISOANTIGENS
SEE BLOOD GROUPS ANTIGENS
BLOOD GROUPS
SEE ALSO TISSUE COMPATIBILITY-TRANSPLANT.
HISTOCOMPATIBILITY TYPING
POlHL-031 74-23 0006 Mechanisms of acute vascular
reaction to injury - Atherosclerotic plaque studies using
mosaic analysis (human)
** R01HL05351-18 Blood group antigens and antibodies
(human, rabbits, sheep)
** POlHL-09011-15 0001 A research and resource program
in blood - Genetic markers of human blood and gene
mapping (human)
** POlHL-09011-15 0012 A research and resource program
in blood - Theoretical population genetics (human)
Molecular pathology of genetic disorders
Genetics of glycosyltransferases in
Pathogenesis of pulmonary
ROlHL-1512507
in man
** ROlHL-20301-02
human blood
ROlHL-21548-01
thromboembolic disease (human, mammals)
BLOOD GROUPS, ABO (H) SYSTEM
SEE ALSO BLOOO GROUP INCOMPATIBILITY PERINATAL. ABO
HEMOLYTIC DISEASE NEWBORN
SEE ALSO IMMUNOLOGY. SECRETORY (ANTIBODY) (FACTOR)
SYSTEM
NOlHB-62970-02 Collection, function and transfusion of
Collection, function and transfusion of
Blood group antigens and antibodies
(human, rabbits, sheep)
ROlHL-151 25-07 Molecular pathology of genetic disorders
in man
** R01HL17881-15 Biosynthesis and degradation of blood
group substances (human, animals)
ROlHL-20301-02 Genetics of glycosyltransferases in
human blood
BLOOD GROUPS, BOMBAY
R01HL-2030I 02 Genetics of glycosyltransferases in
human blood
BLOOD GROUPS, MNSS SYSTEM
ROlHL-05351-18 Blood group antigens and antibodies
(human, rabbits, sheep)
R01HL-2030102 Genetics of glycosyltransferases in
human blood
BLOOD GROUPS, RH SYSTEM
SEE ALSO BLOOD GROUPS ISOANTIBODIES, RH ANTIBODIES
ROlHL-12994-09
R01HL-23I08-01
(human)
ROlHL-2402102
activity (human)
The Rh complex of red cells (human)
Membrane biochemistry of RH antigens
Erythocyte membrane sulfhydrls and Rh
BLOOO GROUPS ANTIGENS
SEE ALSO BLOOD GROUPS
SEE ALSO TISSUE COMPATIBILITY-TRANSPLANT,
ISOALLOANTIGENS
ROlHL-05351-18 Blood group antigens and antibodies
(human, rabbits, sheep)
M Grant has subprojects descnbing specific research aspects
See Appendix for investigator's name and grant number.
POIHI 09011 15 0001 A research and rtuurci program
in blood Genetic marheii of human blood and |gn«
mapping (human)
ROIHL 10036 I'l Biology of red cell *nti|tn antibody
reaction (human)
" ROIHI lll')4 12 Bk)Od group antigent and antibodi*!
(human)
POIHI 1215/ II 0033 Functions and mcchanismi of call
membrane ion transport Immunology aip«cti of active
Na K transport in sheep red cell (alto human, mice)
•• ROIHI 12994 09 The Rh complex of rod cells (human)
ROIHI I4H44 06 Mufou-, glycoprotein in human reipiritory
epithelium (also whr^al)
POIHI 15486 06 0005 Studies on thrombosis Isolation
and characterization of PF4 antigens (rabbits)
ROIHL 16774 04 Genetic epidemiology of hyperlipemia
(Honolulu)
PGOHL 1/265 04 0008 Community blood resource center
support Research Blood genetic markers as biological
probes (human)
BLOOD GROUPS ANTIGENS, II ANTIGENS
** R23HL 21328 02 The I blood group antigen of human
erythrocyte membrane
BLOOD GROUPS ISOANTIBODIES
SEE ALSO TISSUE COMPATIBILITY TRANSPLANT.
ISOALLOANTIBODIES
ROIHL 08696 15 0011 Orthotopic heart transplantation
Transplantation immunology-lmmunodepressive factor
(human, dogs)
*• ROIHL 11154 12 Blood group antigens and antibodies
(human)
P6QHL 1726504 0008 Community blood resource center
support Research- Blood genetic markers as biological
probes (human)
BLOOD GROUPS ISOANTIBODIES, RH
ANTIBODIES
ROIHL 05351-18 Blood group antigens and antibodies
(human, rabbits, sheep)
BLOOD LIPIDS
SEE LIPIDS BLOOD
BLOOD LIPOPROTEIN DISORDERS
SEE LIPOPROTEINS BLOOD. DYSLIPOPROTEINEMIAS
BLOOD OSMOTIC PRESSURE
POIHL 11678-11 0020 Cardiovascular dynamics and their
control ■ Circulatory and pulmonary fluid dynamics during
pulmonary edema
R01HL12493-10 Bioengineering analysis of microvascular
function (cats, rabbits)
P50HL-14218-07 0017 Pulmonary SCOR-Newborn lung
center ■ Transvascular fluid exchange, vasoactive mediators
in ROS (sheep, cat)
P60HL-15162-07 0019 Comprehensive sickle cell center -
RBCBIood rheology in sickle cell anemia and related
disorders (human, animal)
P01HL-1685I-04 0001 Human red cell membrane in
health and disease - Rheology of erythrocyte membrane
(human, amphiuma)
POlHL-16910-05 0001 Regulation of the peripheral
circulation - Quantitative studies of microcirculatory control
(bats)
POlHL-17421-05 0001 Regulation and exchange in the
microcirculation - Mass transfer and microcirculatory
function (rats)
ROlHL-2063401 Blood volume and venous return in
thermal strain (human)
ROlHL-20818-02 Platelet storage at 22 degrees C
(human)
ROlHL-21145-02 Response of atria to hyperosmolality-
Mechanisms (rabbits)
ROIHL 21188-02 Pulsatory water flux and endothelial cell
desquamation
R23HL-2143402 Intrinsic control of coronary blood flow by
chemicals (guinea pigs)
ROlHL-21498-02 Pathophysiology of edema (rats, cats)
BLOOD OSMOTIC PRESSURE, HYPEROSMOLARITY
ROlHL-18288-04 Intraoperative protection of the
myocardium (dogs, rats)
BLOOO OXYGENATORS
SEE CARDIOVASCULAR SURGERY, CIRCULATORY ASSIST
BLOOO OXYGENATORS
BLOOD PLATELET AGGREGATION
SEE BLOOD PUTELETS, PUTELET AGGREGATION
BLOOD PLATELET PRESERVATION
SEE BLOOO PRESERVATION, PLATELET PRESERVATION
BLOOD PLATELET TRANSFUSION
SEE BLOOO TRANSFUSION. PLATELET TRANSFUSION
BLOOD PLATELET TYPING
P01HL-11310-12 Mechanisms of cardiovascular disease
P60HL17265-04 0006 Community blood resource center
support - Research-Evaluation of platelet transfusions
(human, dog)
P01HL-1882702 Platelet vessel wall interactions in
thrombogenesis
(contd)
BLO
P01HL18827-02 0006 Platelet vessel wall Interactions in
thrombogenesis Platelet immune injury in man
ROlHL-20856-02 Platelet transtusions-Usage and
complications (human)
BLOOD PLATELETPHERESIS
SEE BLOOD TREATMENT. PLATELETPHERESIS
BLOOD PLATELETS
SEE ALSO BLOOD AND RE SYSTEM, MEGAKARYOCYTES
NOlHI-32926-10 Analysis of lipoproteins (animals)
RClHL-01601-30 Blood coagulation and hemorrhagic
disease (horseshoe crabs)
ROlHL-01648-31 Blood coagulation and hemophilia (dogs,
swine)
ROlHL-01803-23 0017 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Contractile and relaxing proteins of blood
vessels and platelets (mammals, human)
R01HL0506218 Lipid metabolism in cultured cells
(human, rats, rabbits)
M POlHL-06314-17 Immunologic mechanisms in
cardiovascular disease
** P01HL-063U-17 0047 Immunologic mechanisms in
cardiovascular disease • Role of intravascular coagulation
(human, animals)
POlHL-06314-17 0053 Immunologic mechanisms in
cardiovascular disease - Cellular functions controlled by
cyclic GMP (human, mice, guinea pigs)
ROlHL-07379-13 Structure and function of fibrinogen
(human)
" R01HL08399-15 Platelet injury in infections and allergic
diseases (human)
ROlHL-09902-13 Comparative study of coagulation and
vascular disease (animals)
ROIHL 10582 12 Thrombosis and hemostasis-Analysis,
methods and standards (human, cattle, venom)
M POlHL-11414-11 Thrombosis and atherosclerosis program
** POlHL-1 1414-11 0004 Thrombosis and atherosclerosis
program Platelet function and nonthrombogenic surfaces
(human)
** ROlHL-11775-11 Platelet mechanisms in disease (human,
primates)
** ROIHLI 1880-10 Physiology and pathology of blood
platelets (human, dogs)
•* R01HL13036-08 Coronary thrombosis -Effects on
myocardium and in vivo detection (dogs, monkeys)
*• POlHL-13108-09 0014 Clinical heart transplantation -
Platelets and coagulation in accelerated graft coronary
atherosclerosis
ROlHL-13160-08 Human thrombin (also cattle)
ROlHL-13198-21 Blood coagulation-Physico-chemical
properties (human, cattle)
** POlHL-13262-07 0022 Arterial wall in atherosclerosis -
Mechanisms of platelet prostaglanoln formation
•* R01HL13336-09 Biochemistry and physiology of human
platelets
POlHL-13737-07 0026 Assisted circulation - Hemostatic
mechanism (human, dogs)
POlHL-13738-08 0004 Cardiac assist devices and
artificial hearts - Hematological evaluation of prosthetic
materials (calves)
** ROlHL-14020-06 Characterization of myosin from blood
platelets (rabbit) .
M P50HL-14147-08 Specialized center of research in
thrombosis .
** P50HL-1414708 0001 Specialized center of research in
thrombosis - Role of aspirin, other anti-platelet agents m
platelet function (rat, human)
P50HL-14147-08 0007 Specialized center of research in
thrombosis • Radioactive tracers in recognition of
intravascular coagulation (human, dogs)
P50HL-14147-08 0016 Specialized center of research in
thrombosis Nuclear medicine core laboratory (human,
dogs, rats, rabbits)
P50HL-14147-08 0017 Specialized center of research in
thrombosis Core coagulation laboratory (human)
" P50HL-14147-08 0018 Specialized center of research in
thrombosis - Biochemical aspects of platelet function in
thrombosis and cell growth (human)
P50HL-14164-07 0044 A/S SCOR -Comparative and
experimental atherosclerosis - Cell biology-atherosclerosis
project (pigeons)
P50HL-14217-08 0050 Specialized center of research in
thrombosis • Electron microscopy section (dogs)
" P50HL- 142 17-08 0055 Specialized center of research in
thrombosis Coagulation section-Platelet coagulant activity
(human)
*• P50HL14217-08 0057 Specialized center of research in
thrombosis - Pharmacology-Platelet biochemistry (human,
animal) .
*• P50HL-14217-08 0058 Specialized center of research in
thrombosis Mechanisms of induction and inhibition of
platelet reaction (human, pig)
•* P50HL- 142 17-08 0059 Specialized center of research in
thrombosis - Energy metabolism and platelet function
(human)
P50HL-14217-08 0061 Specialized center ot research in
thrombosis - Pharmacology-Comparison of platelets and
vascular smooth muscle (animal)
P50HL-14217-08 0062 Specialized center of research in
thrombosis - Coagulation section -factor VIII and Factor XII
(human, cattle)
62
P50HL-14217-08 0063 Specialized center of research in
thrombosis - Special clinical studies laboratory
P50HL-14230-07 0093 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Clinical studies involving cellular lipid
content (human)
* P50HL-14230-07 0095 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Blood platelet adherence to endothelial
smooth muscle cells, fibroblast (human)
P50HL-14230-07 0096 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Ultrastructural studies of endothelial cells
(human)
* P50HL-14230-07 0097 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Studies of circulating platelet aggregates
(human)
* ROlHL-14344-07 Platelet function and adenine nucleotide
metabolism (human)
'* ROlHL-14697-07 Role of platelet membranes in
hemostasis (human)
" ROlHL-14890-07 Platelet prostaglandins (human, rabbits)
POlHL-14985-07 0007 Adaptation to hypoxia - Control of
pulmonary circulation, histamine and the sympathetics
(animals)
POlHL-14985-07 0011 Adaptation to hypoxia -
Prostaglandins in the control of the pulmonary circulation
(animals) ,
** R01HL14992-07 Mechanism of thrombin action (human)
POlHL-15195-04 0002 Program project in biological
materials - Structural and surface characterization
** R01HL15226-06 Interaction of blood cells with fibrinogen
and fibrin (human, animals)
" ROlHL-15335-06 The nature of the collagen-platelet
interaction (animals)
P01HL-15486-a6 0005 Studies on thrombosis Isolation
and characterization of PF4 antigens (rabbits)
** ROlHL-15491-06 Blood coagulation-Platelet-plasma
protein interaction (human)
ROlHL-15593-05 Prolonged extracorporeal cardiopulmonary
support (rats, sheep, rabbits)
•* POlHL-15596-05 0012 Coagulation, fibrinolysis,
hemostasis and hepatitis ■ Platelet function-Phorbol ester
and zymosan-induced release activity
** POlHL-15596-05 0014 Coagulation, fibrinolysis,
hemostasis and hepatitis - Von Willebrand factor and
platelet retention in glass bead columns (swine)
" ROIHL- 156 16-04 Platelet membrane proteins in
aggregation (human)
ROlHL-15647-06 Hematopoietic studies of cyclic
hematopoiesis (dogs)
ROlHL-16254-05 Pathogenesis of bubble and clot
formation (fish)
** ROlHL-16355-05 Reactions of thrombin and collagen with
platelets (human)
POlHL-16387-04 0004 The blood vessel and
thrombogenesis - Analysis of vascular basement membrane
by enzymatic methods (human)
POlHL-16411-04 0001 Blood systems in coagulation and
vessel disease - Molecular studies of the role of
complement in blood coagulation (human, rabbits)
POlHL-16411-04 0002 Blood systems in coagulation and
vessel disease - Early stages of coagulation and
cardiovascular disease (human, rabbits)
POlHL-16411-04 0003 Blood systems in coagulation and
vessel disease - Molecular events involving the late stages
of coagulation (rabbits)
** POlHL-164 11-04 0004 Blood systems in coagulation and
vessel disease - Platelets reactions in vascular injury
(human, animals)
POlHL-164 11-04 0006 Blood systems in coagulation and
vessel disease - Factor Vll-lmmunochemistry and
immunobiology (human, mice)
ROlHL-16577-04 Lipoprotein lipase chemistry and function
(rats, cattle, human)
** ROlHL-16634-13 Regulation of metabolism in fibroblasts
and platelets (human, rabbits, sheep)
R01HL16642-05 Biochemistry and pathophysiology ot
plasma kallikrein (human, animals)
R01HL16646-05 Patbobiology of thromboembolic disorders
(human)
ROlHL-167 14-05 Endothelial cell communication in
homeostasis (human, mammals)
ROlHL-16757-04 'Autoimmune' thrombocytopenia (monkey)
ROlHL-16921-05 Synthetic hydrogels as blood tolerable
materials
ROlHL-16938-05 Effect of physical forces on blood (dogs,
t'll'''3n) . . , . i,k;«,\
R01HL-16952-05 Cardiovascular pathology (rats, rabbits)
P01HL17430-05 0005 Control of coagulation - The
activation of prothrombin (human, cattle, dogs)
POlHL-17430-05 0008 Control of coagulation - Cultures
of von Willebrand endothelial cells (pigs)
ROlHL-17487-04 Adrenergic-vasoregulation interactions in
hypertension (human)
ROlHL-17503-03 Vascular bubbles in decompression
sickness (minipig, dog, goat)
*• ROlHL-17513-04 Role of PF-4 in detecting and promotmg
thrombosis (human, primates)
•* ROlHL-17525-03 Molecular basis of collagen-platelet
interaction (human, rat)
** ROlHL-17729-04 Stimulus-response coupling in platelets
(human)
BLO
* POlHL-17812-04 0005 Thrombosis and plasma proteins -
In vitro systems of normal platelets, white cells, sera
(human) .
* POlHL-17812-04 0007 Thrombosis and plasma proteins -
Blood components-Response to endotoxin (dogs, baboons)
* ROlHL-17930-03 Platelet membrane function-Assessment
and application (animals)
■* R01HL17973-04 Cultured aortic endothelial cells (human,
cattle, dogs, swine)
■* R01HL18030-04 The role of contractile proteins in
platelets (human, rabbits)
ROlHL-18179-03 Heart, platelet, and muscle myosins and
actomyosins (cattle) , ^i j .u
POIHL- 18208-04 0001 Center for the study of blood cell
rheology - Physiological basis of reversible erythrocyte
shape change (human, firefly)
** ROlHL-18249-04 Isolation and identification of platelet
membrane (human)
ROIHL 18256-01 Optical properties of platelets and
erythrocytes (rabbits, dogs, human)
** ROIHL 18502-03 Enzymatic regulation of platelet function
(human)
ROlHL-18519-03 Albumin, endothelium and
hemocompatibility (human, dog, cattle, rabbit)
P01HL18576-03 0007 Thrombosis research program
protect - Relationships between coagulability and
thrombosis (human, animals)
•• POlHL-18576-03 0011 Thrombosis research program
project - Proteolysis and platelet function (human, cattle,
rabbits) , , . ■ .,
" ROlHL-18584-03 Effects of physical forces on platelets
•• ROIHL- 18586-03 Role of platelet lipids in hemostasis and
thrombosis (human)
•* ROlHL-18650-03 Platelet collagen interaction (human)
" R01HL18714-04 Cardiovascular matrix-Morphogenesis
and maturation (human, chick embryo, mammal)
M POlHL-18827-02 Platelet vessel wall interactions in
thrombogenesis
POlHL-18827-02 0001 Platelet vessel wall interactions in
thrombogenesis - Role of endothelial cells in the production
of thrombi (human, cattle)
** P01HL18827-02 0006 Platelet vessel wall interactions in
thrombogenesis - Platelet immune injury in man
M P50HL-18828-03 Specialized center of research in
thrombosis .
** P50HL-18828-03 0001 Specialized center of research in
thrombosis - Membrane biology and hemostasis (human)
P50HL-18828-03 0002 Specialized center of research in
thrombosis - Endothelial cell biology (human, guinea pig)
P50HL-18828-03 0004 Specialized center of research in
thrombosis ■ Membrane changes in platelet physiology-Role
of complement (mice, human)
** P50HL-18828-03 0008 Specialized center of research in
thrombosis - Biochemistry, physiology-Platelets and
subcellular platelet particles (human)
** P50HL-18828-03 0009 Specialized center of research in
thrombosis - Platelet formation and megakaryocyte cell
biology (guinea pig, human)
** ROlHL-18935-03 Platelets, fibrinogen, soluble tibrin
interaction (human)
** R01HL-18937-03 Cyclic nucleotides and calcium in
platelets (human)
ROlHL-19001-03 Atherosclerosis in bleeder and drug
treated subjects (pigs)
** ROlHL-19055-03 Platelet function during extracorporeal
perfusion (human, mammals)
ROlHL-19203-03 Surgical approach to congenital heart
diseases (dogs, primates)
** ROlHL-19270-03 Effects of erythropoiesis on platelets ana
hemostasis (rats) .
ROlHL-19323-03 Studies of platelet microtubule protein
ROlHL-19806-03 Chemotactic control of airway phagocytes
(human, rabbits)
** ROlHL-19996-02 Role of membrane proteins in platelet
function (human, rabbits)
-* ROlHL-201 14-02 Collagen-platelet interaction and human
aorta collagen (human)
** ROlHL-20411-03 Platelet fatty acid metabolism in
diabetes (rat, rabbit, guinea pig)
ROlHL-20522-03 Peripheral arterial disease in the diabetic
(human)
" ROlHL-20794-02 Prostaglandin synthesis in human
platelets (also in sheep, rabbit)
** ROlHL-20826-02 Megakaryocyte proliferation and its
control (mice)
ROlHL-20902-02 Studies on marginal band system ot
erythrocytes (amphibians, reptiles, fish)
ROlHL-20924-02 Atherosclerosis and arterial cell functions
(human, rabbits)
** ROlHL-20956-02 Early events following stimulation ot
human platelets , , . , . a
" ROlHL-20971-10 Membrane glycoproteins of platelets ano
leukocytes (human)
** P50HL-21006-02 0004 Specialized center ot research in
arteriosclerosis - Regulation of growth of human arterial
smooth muscle cells by platelets
** P50HL-2 1006-02 0006 Specialized center of research in
arteriosclerosis - Intravascular coagulation and thrombosis
in hyperlipidemia (human)
** R23HL-21 128-02 ATP utilization in platelet contractile
mechanisms (human, rabbits)
(contd)
•tttludes routine methodotogy OR covers only general proiects which preclude
**Onaited significaiitly to above subject.
indexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigators name and grant number.
The mechanisni ol collagen lormation
ROIHL 21217 01 Ion and S hydroxytiYptaniina tiansport by
pittflttt
R23HL 21413 02 Structure and function ol platelet
calcium binding prptain (human)
ROIHL 214/1 02 Structure function studies on actin and
myosin (human, protojoa. labbits. cattle)
R23HI 2149002 Studies ot eniymes in human platelet
membranes
ROIHL 21b92 01 Lipoproteins and coagulation factors in
atherosclerosis (pigeons)
ROIHL 21644 01 Fibronectin and lelated glycopioteins
(human, rodents)
R23HL'2173001 vWagll A new vWD deficient antigen
(human)
ROIHL 2176401 Ultramlcroanalysis ot prostaglandins and
related compounds (rats)
ROIHL 21988 01 Biochemistry of human platelet
chemotaxis
ROIHL 22081 20
(human, cattle)
ROIHL'22119 01 Biochemistry of platelet function in
thrombosis and cell growth (rabbits)
ROIHL'22194'02 Allosteric function of platelet contractile
proteins (human)
ROlHl-2227001 Platelet glycoprotein (human)
ROIHI'2233801 Platelet adhesion and aggregation in a
flow chamber (human)
R23HL'22346 01 Hematological injury and pulmonaiy
dysfunction (human, mammals)
ROIHL 2240601 Isobaric vascular bubbles and
decompression sickness (goats, models)
*• ROIHL 2245501 Platelet concentration in the marginal
layer (dogs, human)
ROlHL-2247101 Biochemistry of prothrombin quick
(human)
** ROlHL-2250201 Role of phosphoinositides in human
platelet secretion
ROlHL'22505-01 Molecular pathology of fibrinogen and
factor XIII (human, animals)
ROlHL-2252701 Prostacyclin-thromboxanes in the
cardiovascular system (human, rabbits)
ROlHL-2257301 Treatment of post surgical
vasoconstriction (dogs, monkeys, human, rats)
ROlHL-2258201 Pulmonary and circulatory alterations
induced by IGE
ROlHL-2258302 Ultrastructural study of endothelium in
thrombosis (human)
M POlHL-2260201 Pathophysiology of the endothelium
•* POlHL-2260201 0001 Pathophysiology of the
endothelium - Platelet-endotbelial interactions in vitro
(human, cattle)
** POlHL-22602-01 0004 Pathophysiology of the
endothelium - Endothelium, platelets smooth muscle and
atherosclerosis (rabbits)
*• POlHL-2263301 0003 Cellular and molecular biology of
lipoprotein metabolism - Sterol metabolism in platelets and
megakaryocytes (human, rabbits, guinea pigs)
** NOlHV-42984-05 Interactions of modified biopolymers with
blood (humans, rats)
BLOOD PLATELETS, PLATELET ACTIVATING
FACTOR
SEE ALSO FATTY ACIDS, UNSATURATED FATTY ACIDS,
THROMBOXANES
POlHL-1 1310-12 0095 Mechanisms of cardiovascular
disease • Blood and transfusion disorders (human, rats,
monkeys)
** ROlHL-17525-03 Molecular basis of collagen-platelet
interaction (human, rat)
ROlHL-1 7747-04 Endothelial injury and regeneration (rats)
M POlHL-1864503 Biology of the artery wall and
atherosclerosis
** POIHL 18645-03 0001 Biology of the artery wall and
atherosclerosis - Primate arterial smooth muscle and
atherosclerosis
POlHL-18645-03 0003 Biology of the artery wall and
atherosclerosis - Synthesis of connective tissue proteins by
smooth muscle cells (human, monkeys)
POlHL-18645-03 0005 Biology of the artery wall and
atherosclerosis - Effects of atherosclerosis risk factors on
endothelium of the primate
** POlHL-18645-03 0006 Biology of the artery wall and
atherosclerosis - The platelet and atherosclerosis (monkeys,
baboons)
•* P50HL-18828-03 0005 Specialized center of research in
thrombosis - Platelet inflammatory factors in thrombosis
(human, guinea pig)
P50HL-18828-03 0008 Specialized center of research in
thrombosis - Biochemistry, physiology -Platelets and
subcellular platelet particles (human)
ROlHL-21533-02 Platelet inhibitor drug in coronary surgery
(human)
ROlHL-21565-02
(rats, rabbits)
ROlHL-22555-01
Pathogenesis of inflammatory lung injury
Structure and function of platelet
activating factor (rabbits, human)
BLOOD PLATELETS, PLATELET AGGREGATION
SEE ALSO BLOOD COAGUUTION. ANTICOAGULANTS. PUTELET
AGGREGATION INHIBITORS
ROlHL-01648-31 Blood coagulation and hemophilia (dogs,
swine)
ROlHL-01661-27 Hemostatic mechanisms (human)
«3
ROIHl 01803 23 0014 ArtfrlOWlWMll. Itomerulanephrltii.
rheumatic fever Regenerated tndolhlllum on lipid
accumulation in arterial wall (rabbit)
ROIML 03424 21 lormnlioii nnd properlioj ot prolhrombin
derivatives (human, animals)
POIHL 04664 18 0008 Cardiovascular and lung dynamlci
Micrographic video imaging technique
' POIHI U6312 1/ 0046 Surgical cardiology The
lelalionship of pioslaglandins to heart disease
POIHL 06350 17 0005 Hemostasis research program
project Purification of plasma antihemophilic factor
(human)
' P01H106350 17 0019 Hemostasis research program
pioiect Microcirculation (human, rats, rabbits)
POIHL 06835 17 0063 Cardiovascular disease Studies
on prostaglandins (human, rabbits)
POIHL 07896 15 0057 Environmental biomedical research
program Effects of dipyridamole and aspirin on
decompression thrombocytopenia (human)
• POIHL 11310 12 0095 Mechanisms of cardiovascular
disease Blood and transfusion disorders (human, rats,
monkeys)
POIHL 11414 11 0037 Thrombosis and atherosclerosis
program Vascular intimal injury and healing (rabbits,
rats)
ROlHL-11775-11 Platelet mechanisms in disease (human,
primates)
ROIHL 11802 10 Cardiovascular surgical research (dogs.
sheep, swine, cats, monkeys)
ROIHL 11880-10 Physiology and pathology of blood
platelets (human, dogs)
ROIHL 11897-11 Pathogenesis of experimental
atherosclerosis (rabbits, guinea pigs)
R01HL-11945-10 Synthesis of artificial lung and kidney
systems (sheep, mice, swine)
ROlHL-12839-09 Flow, transport and membrane
phenomena in blood (human)
ROIHL 13198-21 Blood coagulation- Physico-chemical
properties (human, cattle)
P01HL-13330-08 0056 Mechanical circulatory support -
Blood compatibility linings (calves)
ROIHL 13336-09 Biochemistry and physiology of human
platelets
' ROlHL-13466-08 Pulmonary platelets in shock, trauma
and embolization (dogs, pigs, rats)
P50HL-14147-08 0001 Specialized center of research in
thrombosis - Role of aspirin, other anti-platelet agents in
platelet function (rat. human)
P50HL-14147-08 0012 Specialized center of research in
thrombosis - Tissue culture study of arterial cells (human,
hamster)
P50HL-14147-08 0017 Specialized center of research in
thrombosis - Core coagulation laboratory (human)
P50HL-142 14-07 0031 Newborn lung center for hyaline
membrane disease - Essential fatty acid deficiency and
HMD (human)
P50HL-14217-08 Specialized center of research in
thrombosis
P50HL-142 17-08 0051 Specialized center of research in
thrombosis - Microcirculation section (bat. hamster)
P50HL-14217-08 0054 Specialized center of research in
thrombosis - Coagulation section-Platelet aggregation
(human, pig. rabbit, dog)
P50HL-14217-08 0055 Specialized center of research in
thrombosis - Coagulation section -Platelet coagulant activity
(human)
P50HL-142 17-08 0057 Specialized center of research in
thrombosis - Pharmacology-Platelet biochemistry (human,
animal)
P50HL-142 17-08 0058 Specialized center of research in
thrombosis - Mechanisms of induction and inhibition of
platelet reaction (human, pig)
P50HL-1421708 0059 Specialized center of research in
thrombosis - Energy metabolism and platelet function
(human)
P50HL-142 17-08 0061 Specialized center of research in
thrombosis - Pharmacology-Comparison of platelets and
vascular smooth muscle (animal)
P50HL-14217-08 0063 Specialized center of research in
thrombosis - Special clinical studies laboratory
P50HL- 142 30-07 A/S SCOR-Lipids, atherosclerosis and
thrombosis
P50HL-14230-07 0094 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Studies of atherosclerosis and regression
(monkeys)
P50HL-14230-07 0095 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Blood platelet adherence to endothelial
smooth muscle cells, fibroblast (human)
P50HL-14230-07 0097 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Studies of circulating platelet aggregates
(human)
P50HL-14230-07 0098 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Molecular properties of factor VIII (cattle,
human, mice)
ROIHL 14344-07 Platelet function and adenine nucleotide
metabolism (human)
ROlHL-14595-07 Primary disorders of platelet function
(human, rats)
ROlHL-14697-07 Role of platelet membranes in
hemostasis (human)
ROlHL-14890-07 Platelet prostaglandins (human, rabbits)
'Excludes routine methodok>gy OR covers only general projects which preclude indexing
••Oriented significanthi to above subject.
at the specific level.
M Grant has subprojects descnbing specific research aspects
See Appendix for investigator's name and grant number.
•ID
POIHI 14985 0/ 0014 Adaptation lo hypoxia High
attitude pulmonary edema (human, raft, dogil
ROIHl 14992 0/ Mechanitm of thrombin action (human)
POIHI 15195 04 0004 Program project in biological
materials Biological evaluation and turtace interaction
studies (dogs)
ROIHL 15215 06 Role of complement in inliavaicular
coagulation (rabbits, mice)
ROIHl 15226 06 Interaction of blood celli with fibrinogen
and fibrin (human, animals)
ROIHl 15230 05 Molecular basis of V Witlebrand'l OlMtM
and hemophilia (human, cattle)
ROIHl 15335 06 The nature of the collagen platelet
interaction (animals)
ROIHl 154/4 06 Structure and function of the
antihemophilic factor (human, cattle)
POIHL 15486 06 0004 Studies on thrombosis
Thrombosis, intravascualr coagulation, platelet aggregation
(dogs)
ROIHL 15491 06 Blood coagulation Platelet plasma
protein interaction (human)
' POIHL 1559605 0012 Coagulation, fibrinotysis.
hemostasis and hepatitis Platelet function Phorbol ester
and zymosan induced release activity
ROIHL 1561506 Structure function studies of human
factor VIII/vWF
' ROIHL 15616 04 Platelet membrane proteins in
aggregation (human)
ROIHL 15681 06 Coronary flow studies of partially
obstructed vessels (dogs)
' POIHL 15835-06 0004 Study of muscles related to heart
disease Actomyosin systems and cell motility (slime
molds, human)
' P60HL-1599606 0001 Cincinnati comprehensive sickle
cell center - Coagulation mechanisms in sickle cell disease
(human)
ROlHL-16355-05 Reactions of thrombin and collagen with
platelets (human)
POlHL-16387-04 0005 The blood vessel and
thrombogenesis - Fluid engineering considerations in
thrombogenesis
ROlHL-16634-13 Regulation of metabolism in fibroblasts
and platelets (human, rabbits, sheep)
R01HL-16720-02 Platelet aggregation (human)
R01HL-16938-05 Effect of physical forces on blood (dogs.
human)
P60HL-1 7265-04 0007 Community blood resource center
support - Research-Massive transfusion and trauma
(human)
ROIHL 17355-04 Pulmonary vascular adjustments in
circulatory collapse (dogs, rats)
P01HL17430-05 Control of coagulation
P01HL17430-05 0001 Control of coagulation - Porcine
von Willebrand's disease
POlHL-17430-05 0002 Control of coagulation - Isolation
of ristocetin-von Willebrand factor (swine)
POlHL-17430-05 0007 Control of coagulation - Platelet
adhesion, aggregation, ultrastructure in flowing blood
(human, animals)
ROlHL-17462-03 Role of glycosphingolipids in platelet
aggregation (rats, human, dogs)
ROIHL- 175 13-04 Role of PF-4 in detecting and promoting
thrombosis (human, primates)
ROIHL-17516-04 Role of androgen as a risk factor in
atherogenesis (human, animals)
ROIHL- 17623-05 Initial events in thrombus formation on
surfaces (human, rats)
ROlHL-17729-04 Stimulus-response coupling in platelets
(human)
ROlHL-17769-03 New methods of studying blood
coagulation kinetics
POlHL-17812-04 Thrombosis and plasma proteins
POlHL-17812-04 0004 Thrombosis and plasma proteins -
Serum-platelet interaction (human)
POlHL-17812-04 0005 Thrombosis and plasma proteins -
In vitro systems of normal platelets, white cells, sera
(human)
ROlHL-18030-04 The role of contractile proteins in
platelets (human, rabbits)
ROlHL-18239-03 Dietary fat composition and
prostaglandin synthesis (rats)
R01HL-18256-01 Optical properties of platelets and
erythrocytes (rabbits, dogs, human)
ROlHL-18288-04 Intraoperative protection of the
myocardium (dogs, rats)
ROlHL-18321-03 Fluid shear or magnetic alignment of
blood components (human)
ROlHL-18502-03 Enzymatic regulation of platelet function
(human)
POIHL-18576-03 0001 Thrombosis research program
project - Platelet damage from physical forces and
artificial surfaces (human)
POlHL-18576-03 0004 Thrombosis research program
project - Mechanism and control of collagen-platelet
interaction
P01HL18576-03 0005 Thrombosis research program
project - Molecular basis of von Willebrand's disease and
hemophilia (human, cattle)
POlHL-18576-03 0011 Thrombosis research program
project - Proteolysis and platelet function (human, cattle,
rabbits)
(contd)
BLO
** R01HL-1858A03 Effects of physical forces on platelets
(human)
ROlHL-18625-03 Organization of arterial ground substance
(cattle)
•* ROlHL-1865003 Platelet collagen interaction (human)
ROlHL-187 14-04 Cardiovascular matrix-Morphogenesis
and maturation (human, chick embryo, mammal)
POlHL-18827-02 0003 Platelet vessel wall interactions in
thrombogenesis - Tumor cell and platelets in
thrombogenesis and metastasis (human, animals)
** POlHL-18827-02 0005 Platelet vessel wall interactions in
thrombogenesis - Platelet vessel wall interactions in
thrombogenesis (human)
M P50HL-18828-03 Specialized center of research in
thrombosis
P50HL-18828-03 0001 Specialized center of research in
thrombosis ■ Membrane biology and hemostasis (human)
** P50HL-18828-03 0004 Specialized center of research in
thrombosis ■ Membrane changes in platelet physiology-Role
of complement (mice, human)
*• PbOHL-18828-03 0005 Specialized center of research in
thrombosis - Platelet inflammatory factors in thrombosis
(human, guinea pig)
** P50HL-18828-03 0008 Specialized center of research in
thrombosis • Biochemistry, physiology-Platelets and
subcellular platelet particles (human)
ROlHL-18932-03 Brain microcirculation observed in vivo
after trauma (mice)
ROlHL-18935-03 Platelets, fibrinogen, soluble fibrin
interaction (human)
** ROlHL-18937-03 Cyclic nucleotides and calcium in
platelets (human)
** ROlHL-19001-03 Atherosclerosis in bleeder and drug
treated subjects (pigs)
ROlHL-19055-03 Platelet function during extracorporeal
perfusion (human, mammals)
ROlHL-19255-03 Evaluation of diagnostic clinical
hemorrheology (human)
*' ROlHL-19278-03 Ristocetin induced platelet aggregation
(human)
ROlHL-19323-03 Studies of platelet microtubule protein
P50HL-19362-02 0006 A/S SCOR -Atherosclerosis in
nonhuman primates • Effects of cigarette smoking on
atherosclerosis (baboon)
** ROlHL-19993-02 Optical detection of platelet aggregates
(human, baboons)
ROlHL-20079-02 0001 Thromboresistant material ■ Active
and passive thromboresistant surfaces
ROlHL-20079-02 0002 Thromboresistant material -
Thromboresistant materials (sheep)
ROlHL-20079-02 0003 Thromboresistant material ■ Blood
surface interactions (human, cattle)
ROlHL-201 14-02 Collagen-platelet interaction and human
aorta collagen (human)
** ROlHL-20140-02 Glycoproteins of platelet membrane and
platelet function (human)
** ROlHL-20337-02 Thromboembolic diseases (human)
ROlHL-20411-03 Platelet fatty acid metabolism in
diabetes (rat. rabbit, guinea pig)
ROlHL-20517-03 Diabetes, somatotropin, factor VIII and
atherosclerosis (human, animal)
ROlHL-20520-03 Protein modification-The key to diabetic
sequelae (human, animal)
** ROlHL-20563-02 Restoring microcirculation after platelet
aggregation
ROlHL-20787-02 Thromboxanes and prostaglandins-
Biochemical pharmacology (rabbits, human)
** ROlHL-21001-01 Protein and thrombus deposition on
vascular grafts
** R23HL-21128-02 ATP utilization in platelet contractile
mechanisms (human, rabbits)
ROlHL-21239-02 Isolation and mechanism of action of
thromboxane A2 (human, rabbits)
ROlHL-21487-01 Molecular characterization of
Glanzmann's thrombasthenia (human)
R23HL-2 1490-02 Studies of enzymes in human platelet
membranes
ROlHL-21565-02 Pathogenesis of inflammatory lung iniury
(rats, rabbits)
ROlHL-21769-01 Blood compatible benzamidine containing
polymers
** ROlHL-21988-01 Biochemistry of human platelet
chemolaxis
•* P01HL22163-01 0001 Surface thrombogenesis -
Mechanisms and prevention - Initial blood protein and
platelet interactions with biomaterials (baboons)
POlHL-22163-01 0002 Surface thrombogenesis -
Mechanisms and prevention - Laser-scattering detection of
microemboli in blood flow (baboons)
ROlHL-22219-01 Prostacyclin and peroxides in blood and
membrane disease
** ROlHL-22338 01 Platelet adhesion and aggregation in a
flow chamber (human)
ROlHL-22355-01 Purification, structure and function of
factor VIII (human)
** ROlHL-224 15-01 Mechanisms responsible for disease
severity in asthma (human)
ROlHL-22445-01 Platelet inhibitors -Effect on coronary
bypass grafts (dogs)
ROlHL-22502-01 Role of phosphoinositides in human
platelet secretion
64
ROlHL-22582-01 Pulmonary and circulatory alterations
induced by IGE
** ROlHL-22585-01 Plasma proteins adsorbed to artificial
organs (human, rabbits)
POlHL-22602-01 0001 Pathophysiology of the
endothelium - Platelet-endothelial interactions in vitro
(human, cattle)
R23HL-22621-01 Blood cell-mediated pulmonary (human)
** POlHL-22633-01 0003 Cellular and molecular biology of
lipoprotein metabolism - Sterol metabolism in platelets and
megakaryocytes (human, rabbits, guinea pigs)
** ROlHL-22738-01 Role of bioelectric potentials in platelet
adherence (bats, rats, hamsters)
ROlHL-22739-01 Evolution and progression of pediatric
atherosclerosis
** ROlHL-22946-01 Prostaglandins, platelet aggregation and
vasoactivity (human, rats, rabbits)
** ROlHL-22951-01 Studies on the affect of vitamin E on
platelets (human, rats)
** ROlHL-230 10-01 Control and mechanism of platelet
aggregation (human)
** ROlHL-231 14-01 Control of platelet aggregation in shock
(dogs, rabbits)
ROlHL-23899-01 Flow and flexing at blood/biomaterial
interfaces
** NOlHV-52907-04 Interactions of platelets with collagens
(human, mammals)
BLOOD PLATELETS DEFECTS QUALITATIVE
SEE BLOOD PLATELETS DISORDERS. THROMBOCYTOPATHY
BLOOD PLATELETS DISORDERS
SEE ALSO BLOOD AND RE DISORDERS. HEMORRHAGIC
DISORDERS
SEE ALSO BLOOD COAGULATION DISORDERS
** POlHL-06314-17 0047 Immunologic mechanisms in
cardiovascular disease - Role of intravascular coagulation
(human, animals)
** ROlHL-09902-13 Comparative study of coagulation and
vascular disease (animals)
ROlHL-10582-12 Thrombosis and hemostasis -Analysis,
methods and standards (human, cattle, venom)
** ROlHL-11880-10 Physiology and pathology of blood
platelets (human, dogs)
** ROlHL-13629-08 Hemorrhagic diseases (human)
ROlHL-13754-08 Postoperative thromboembolism in
surgical patients (human)
** P50HL-142 17-08 0059 Specialized center of research in
thrombosis - Energy metabolism and platelet function
(human)
** ROlHL-14595-07 Primary disorders of platelet function
(human, rats)
ROlHL-14637-05 Thrombopoietin -Immunoassay and
characterization (mice)
ROlHL-15616-04 Platelet membrane proteins in
aggregation (human)
ROlHL-161 54-05 Membrane lung perfusion for acute
respiratory failure (sheep, baboons)
POlHL-16387-04 0009 The blood vessel and
thrombogenesis - Role of pituitary gland in the
pathogenesis of arteriosclerotic lesions (rats)
ROlHL-16720-02 Platelet aggregation (human)
" POlHL-17430-05 0007 Control of coagulation • Platelet
adhesion, aggregation, ultrastructure in flowing blood
(human, animals)
ROlHL-17462-03 Role of glycosphingolipids in platelet
aggregation (rats, human, dogs)
POlHL-17812-04 0002 Thrombosis and plasma proteins -
Activators of fibrinolysis -Synthesis and degradation
(human, cattle)
ROIHL 18586-03 Role of platelet lipids in hemostasis and
thrombosis (human)
** ROlHL-18650-03 Platelet collagen interaction (human)
R01HL-18815-03 Surgical vascular disorders (human,
dogs)
** POlHL-18827-02 0006 Platelet vessel wall interactions in
thrombogenesis - Platelet immune injury in man
** ROlHL-19996-02 Role of membrane proteins in platelet
function (human, rabbits)
ROlHL-20140-02 Glycoproteins of platelet membrane and
platelet function (human)
ROlHL-204 11-03 Platelet fatty acid metabolism in
diabetes (rat, rabbit, guinea pig)
ROlHL-20794-02 Prostaglandin synthesis in human
platelets (also in sheep, rabbit)
** ROlHL-21460-02 Lipoproteins, hemostasis and
atherosclerosis (human, rabbits)
BLOOD PLATELETS DISORDERS,
THROMBOCYTHEMIA, HEMORRHAGIC
ROlHL-01601-30 Blood coagulation and hemorrhagic
disease (horseshoe crabs)
ROIHL-19270-03 Ettects of erythropoiesis on platelets and
hemostasis (rats)
" POlHL-22602-01 0001 Pathophysiology of the
endothelium - Platelet-endothelial interactions in vitro
(human, cattle)
POlHL-22602-01 0004 Pathophysiology of the
endothelium - Endothelium, platelets smooth muscle and
atherosclerosis (rabbits)
BLO
BLOOD PLATELETS DISORDERS,
TH ROMBOCYTOPATH Y
SEE ALSO BLOOD COAGULATION DISORDERS, VON
WILLEBRANDS DISEASE
R01HL02254-23 Blood coagulation and hemorrhagic
disease (human, animals)
ROlHL-07652-14 Destruction of red blood cells in
hemolytic anemias (human, guinea pigs)
ROlHL-09902-13 Comparative study of coagulation and
vascular disease (animals)
P50HL-14217-08 0059 Specialized center of research in
thrombosis - Energy metabolism and platelet function
(human)
ROlHL-14595-07 Primary disorders of platelet function
(human, rats)
ROlHL-15616-04 Platelet membrane proteins in
aggregation (human)
** ROlHL-21487-01 Molecular characterization of
Glanzmann's thrombasthenia (human)
ROlHL-23010-01 Control and mechanism of platelet
aggregation (human)
BLOOD PLATELETS DISORDERS,
TH ROMBOCYTOPEN lA
" POlHL-07896-15 0057 Environmental biomedical research
program - Effects of dipyridamole and aspirin on
decompression thrombocytopenia (human)
R01HL11880-10 Physiology and pathology of blood
platelets (human, dogs)
P50HL-14217-08 0055 Specialized center of research in
thrombosis - Coagulation section-Platelet coagulant activity
(human)
ROlHL-14739-06 The role of leukocytes in thrombotic
disease (human, dogs)
P01HL-14985-07 0007 Adaptation to hypoxia - Control of
pulmonary circulation, histamine and the sympathetics
(animals)
ROIHL 15593-05 Prolonged extracorporeal cardiopulmonaty
support (rats, sheep, rabbits)
ROlHL-15647-06 Hematopoietic studies of cyclic
hematopoiesis (dogs)
POlHL-16411-04 0004 Blood systems in coagulation and
vessel disease - Platelets reactions in vascular injury
(human, animals)
ROIHL 16646-05 Pathobiology of thromboembolic disorders
(human)
ROlHL-16714-05 Endothelial cell communication in
homeostasis (human, mammals)
** ROlHL-16757-04 'Autoimmune' thrombocytopenia (monkey)
P60HL-17265-04 0006 Community blood resource center
support - Research-Evaluation of platelet transfusions
(human, dog)
POlHL-18576-03 0007 Thrombosis research program
project - Relationships between coagulability and
thrombosis (human, animals)
POlHL-18645-03 0006 Biology of the artery wall and
atherosclerosis - The platelet and atherosclerosis (monkeys,
baboons)
ROlHL-19203-03 Surgical approach to congenital heart
diseases (dogs, primates)
ROlHL-20140-02 Glycoproteins of platelet membrane and
platelet function (human)
ROlHL-20818-02 Platelet storage at 22 degrees C
(human)
ROlHL-20856-02 Platelet transfusions-Usage and
complications (human)
ROlHL-20924-02 Atherosclerosis and arterial cell functions
(human, rabbits)
ROlHL-21429-02 Transport of LDL in arterial wall (human,
mammals)
ROlHL-21565-02 Pathogenesis of inflammatory lung injury
(rats, rabbits)
BLOOD PLATELETS DISORDERS,
THROMBOCYTOPENIC PURPURA
** ROlHL-13336-09 Biochemistry and physiology of human
platelets
•* ROlHL-13629-08 Hemorrhagic diseases (human)
P60HL-17265-04 0006 Community blood resource center
support - Research-Evaluation of platelet transfusions
(human, dog)
** POlHL-18576-03 0011 Thrombosis research program
project - Proteolysis and platelet function (human, cattle,
rabbits)
POlHL-18827-02 0006 Platelet vessel wall interactions in
thrombogenesis - Platelet immune injury in man
P50HL-18828-03 0005 Specialized center of research in
thrombosis ■ Platelet inflammatory factors in thrombosis
(human, guinea pig)
BLOOD PRESERVATION
SEE ALSO BLOOD AND RE SYSTEM, BLOOD FRACTIONATION
*♦ ROIHL 07449-17 Formation and survival of red blood cells
(human)
M POlHL-09011-15 A research and resource program in
blood
POlHL-09011-15 0017 A research and resource program
in blood - Operations research laboratory
♦* P01HL09011-15 0022 A research and resource program
in blood - Cryopreservation of blood components (human)
ROlHL-11154-12 Blood group antigens and antibodies
(human)
(contd)
•Excludes routine melhodokigy OR covers onhi general projects which preclude
"Oriented significantly to above subiect
indexing at the specific level.
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
National blood banking data needs
Collection, function and transfusion ol
Collection, (unction and transtusion of
Collection, function and transtusion of
Collection, (unction and transfusion of
BLO
ROIMI is;?? 06 Htmorthaoloiy studies related to in wn/o
blood (low (human)
•• ROIHI 16931 04 Red cell s(ora|e and (ians(usion
(human, animals)
M P60HI i;?65 0< Community blood resource center support
P60HL i;?6b04 0001 Community blood resource center
support Demonstration and evaluation
P60HL 1/26S04 000? Community blood resource center
support Research Massive transtusion and trauma
(human)
•• ROlHl 1/47904 Blood storage The production o(
cardiotoiic material (dogs, human, swine)
ROlHl ??6?1 01 Removal o( senescen( and s(ored human
red cells
BLOOD PRESERVATION, BLOOD BANKS,
CENTERS-RESOURCES-REGISTRIES
NOIHB 62967 03 Blood banking seivices on a regional
basis
"• N01HB62968-07
N01H8 6297002
granulocytes
NOlHB-6297103
granulocytes
NOlHB-62972 05
granulocytes
NOlHB-6297305
granulocytes
•' P01HL0901115 0017 A research and resource program
in blood Operations research laboratory
•• P01HL0901115 0022 A research and resource program
in blood Cryopreservation of blood components (human)
R01HL13567 06 Ion transport across cell membranes
(human)
** ROIHL 13881 08 The American Red Cross National
Fractionation Center
ROIHL 15722-06 Hemorrheology studies related to in vivo
blood flow (human)
M P60HL 1726504 Community blood resource center support
P60HL1 7265-04 0001 Community blood resource center
support - Demonstration and evaluation
P60HL- 17265-04 0010 Community blood resource center
support ■ Blood resources educational program
BLOOD PRESERVATION, LEUKOCYTE
PRESERVATION
P60HL-1 7265-04 0009 Community blood resource center
support - Research -Developing granulocyte transfusion
therapy (human, rabbit)
ROlHL-1747904 Blood storage-The production of
cardiotoxic material (dogs, human, swine)
BLOOD PRESERVATION, PLATELET
PRESERVATION
** ROlHL-13629-08 Hemorrhagic diseases (human)
P50HL-14217-08 0055 Specialized center of research in
thrombosis ■ Coagulation section-Platelet coagulant activity
(human)
P60HL-1 7265-04 0006 Community blood resource center
support - Research -Evaluation of platelet transfusions
(human, dog)
Enzymatic regulation of platelet function
ROIHL-18502-03
(human)
ROlHL-19323-03
ROlHL-19996-02
Studies of platelet microtubule protein
Role of membrane proteins in platelet
function (human, rabbits)
ROlHL-20666-02 Cell biology of platelet preservation
(human)
** R01HL-20695-02
** ROlHL-20716-02
platelets (rats)
** R01HL-207I8-02
platelets
** ROlHL-20788-02
transfusion
** ROlHL-20818-02
(human)
Stored plateletes (human)
Freezing and electromagnetic thav»ing of
Microstructural integrity of stored human
Preservation of human platelets for
Platelet storage at 22 degrees C
BLOOD PRESSURE
SEE CARDIOVASCULAR FUNCTION, BLOOD PRESSURE
BLOOD PRESSURE GRADIENT TECHNIQUE
SEE CARDIOVASCULAR DISORDERS DIAGNOSIS BLOOD
PRESSURE GRADIENT TECHNIQUE*
BLOOD PROTEINS
SEE ALSO ALBUMINS. SERUM ALBUMIN
SEE ALSO BLOOD COAGUUTION
SEE ALSO BLOOD PROTEINS DISORDERS
SEE ALSO GLOBULINS. CORTICOSTEROID BINDING GLOBULIN
SEE ALSO GLOBULINS. SERUM GLOBULINS
SEE ALSO HALOPROTEINS. THYROXINE BINDING PROTEINS
SEE ALSO HEMOPROTEINS. HAPTOGLOBINS
SEE ALSO HEMOPROTEINS. HEMOGLOBIN
SEE ALSO IMMUNOLOGY, COMPLEMENT
SEE ALSO METALLOPROTEINS. CERULOPLASMIN
SEE ALSO METALLOPROTEINS. FERRITIN
SEE ALSO METALLOPROTEINS, HEMERYTHRIN
SEE ALSO MHALLOPROTEINS. HEMOCYANIN
SEE ALSO METALLOPROTEINS. TRANSFERRIN
N01HI-32926-1Q Analysis of lipoproteins (animals)
ROlHL-02262-23 Mechanisms regulating plasma proteins
and solutes (human, dogs)
65
POIHL 0.11/4 ?3 0009 Mechanisms ol icul* vascular
rtJition lo iniury Mast cell lipid interaction (human, rats)
M POIHI 09011 I'j A research and resource program in
blood
•• POIHI 0901 1 I'j 000? A research and resource program
in blood Biosynthesis ol librinogen (dogs)
ROIHI 09/39 IJ Biophysical studios of proteins (human)
POIHI 116/8 II 0036 Cardiovascular dynamics and their
control Pulmonary capillary dynamics and edema (dogs)
POIHL 12157 11 0055 functions and mechanisms of cell
membrane ion transport Growth and development of
synthetic strand heart cells in culture (chick embryo)
ROIHL 12421 10 Pathophysiology of circulatory shock
(dogs, baboons)
ROIHL 12839 09 Flow, transport and membrane
phenomena in blood (human)
ROIHL 13596 07 Clearance of plasma proteins from
alveoli
POIHL 1373808 0004 Cardiac assist devices and
artificial hearts Hematological evaluation of prosthetic
materials (calves)
ROIHL 13881 08 The American Red Cross National
Fractionation Center
P50HL 14147 08 0006 Specialized center of research in
thrombosis Clearance mechanisms of coagulation
moieties (human, labbits. rodents)
P60HL-1516905 0018 Support for center (or sickle cell
disease Studies on sickle cell disease (human, rats,
dogs)
POIHL 15195-04 0002 Program project in biological
materials Structural and surface characterization
** ROlHL-15491 06 Blood coagulation -Platelet-plasma
protein interaction (human)
ROlHL-15520-06 Total blood replacement by fluorocarbons
and polyols (rats)
POlHL-15596-05 0017 Coagulation, fibrinolysis.
hemostasis and hepatitis - Heparin and antithrombin III
POlHL-15596-05 0020 Coagulation, fibrinolysis.
hemostasis and hepatitis - Affinity chromatography
ROlHL-15646 03 Lipid studies in vascular smooth muscle
cells (human, monkeys)
P60HL-15999-05 0020 Miami comprehensive sickle cell
center - Deficiency in complement dependent humoral
immunity -Sickle cell disease (human)
R01HL-16601-05 Structure and function of blood proteins
(human, cattle)
R01HL-I6921-05 Synthetic hydrogels as blood tolerable
materials
P60HL-17265-04 0002 Community blood resource center
support - Research-Human factor VIII
P60HL-17265-04 0003 Community blood resource center
support - Research-Human factor IX-Role in intrinsic
clotting (also baboons, dogs)
P01HL-I7430-05 0002 Control of coagulation - Isolation
of ristocetin-von Willebrand factor (swine)
ROlHL-17623-05 Initial events in thrombus formation on
surfaces (human, rats)
^i POlHL-17812-04 Thrombosis and plasma proteins
POlHL-17812-04 0001 Thrombosis and plasma proteins -
Thrombosis and plasma proteins (cattle, guinea pigs)
POlHL-1781204 0004 Thrombosis and plasma proteins -
Serum-platelet interaction (human)
POlHL-17812-04 0005 Thrombosis and plasma proteins -
In vitro systems of normal platelets, white cells, sera
(human)
* POlHL-17812-04 0007 Thrombosis and plasma proteins -
Blood components-Response to endotoxin (dogs, baboons)
ROlHL-17995-04 Cellular synthesis and release of
mucopolysaccharides (rabbits)
ROlHL-18010-04 Capillary transport of large molecules
(dogs, sheep)
ROlHL-18012-04 Cellular defects in nocturnal
hemoglobinuria (human)
R01HL-I8321-03 Fluid shear or magnetic alignment of
blood components (human)
ROlHL-18473-04 Genesis of atherosclerotic lesions
(human, mules)
* ROlHL-185 19-03 Albumin, endothelium and
hemocompatibility (human, dog. cattle, rabbit)
* P50HL-191 57-02 0008 Studies in cystic fibrosis and
bronchiolitis - Serum proteins in cystic fibrosis (human)
ROlHL-193 16-03 Study of glomerular permeability (fish.
turtle, frog, chordates, Crustacea)
ROlHL-19399-02 Atherosclerosis-Early events and
regression factors (rats)
* ROlHL-19419-03 Cellular interactions with foreign
materials (mammals)
R01HL-I9539-03 Pathology of hypertensive-associated
arteritis (rabbits)
ROlHL-20079-02 0001 Thromboresistant material - Active
and passive thromboresistant surfaces
■ ROlHL-20079-02 0003 Thromboresistant material - Blood
surface interactions (human, cattle)
ROlHL-20 106-02 Coupling of platelet contractile proteins
to fibrin (human)
ROlHL-2030102 Genetics of glycosyltransferases in
human blood
ROIHL 20846-02 Purification of bovine plasminogen
proactivator
P50HL-21006-02 0003 Specialized center of research in
arteriosclerosis - Transport of vitamin A in plasma (human
rat)
BLO
Mechaniimt of reeipantion pulmofiary
*&dudes iDutioe methodokigy OR covers only general projects which preclude indexing
Oriented significantly to above subject
at the specific level.
M Grant has subprojects descnbing specific research aspects
See Appendix for investigators name and grant number.
R71HI 71050 07
edema (ribbitil
ROIHI 71498 02 Pathophyiiolofy of edema (rati, call)
RUIHI 2154801 Pttho|tn«tis ol pulmonary
thromboembolic diteatt (human, mammali)
ROIHI 7159201 lipoproleini ind coi|ulitton fictori In
atherosclerosis (pigeons)
ROIHI 7164401 Fibronectin and related (tycoprottini
(human, rodents)
•* ROIHI 71/91 01 Precipitation of proteins with poly
(ethylene glycol) (human)
ROIHI 21988 01 Biochemistry ol human platelet
chemotaiis
•• POIHI 77163 01 0001 Surface thrombogenesis
Mechanisms and prevention Initial blood protein and
platelet interactions with biomaterials (baboons)
POIHI 22163 01 0003 Surface thrombogenesis
Mechanisms and prevention In vivo mechanisms of
biomaterial thrombogenesis and its prevention (baboons)
*• ROIHL 22530 01 Active site studies on blood proteases
(human)
ROIHL 22569 02 Intestinal secretion Capillary and tissue
forces (dogs, cats)
** ROIHL 22585 01 Plasma proteins adsorbed lo artificial
organs (human, rabbits)
*• POIHL 22602 01 0002 Pathophysiology of the
endothelium Molecular charge and endothelial
permeability (rats, mice)
•* R23HL 22933 01 Transvascular fluid and protein exchange
in the lung (sheep)
" ROIHL 2389901 Flow and flexing at blood/biomaterial
interfaces
•• NOlHR.72923-01 Cystic fibrosis factor identification and
quantification (human)
** NOlHV-32917 08 Materials development and testing
BLOOD PROTEINS DISORDERS
SEE ALSO HEMOPROTEINS. HEMOGLOBIN. METHEMOGLOBIN
SEE ALSO HEMOPROTEINS. METHEMOGLOBINEMIA
SEE ALSO LIPOPROTEINS BLOOD. DYSLIPOPROTEINEMIAS
POlHL-09011-15 0005 A research and resource program
in blood Characterization of hepatitis-B antigen and the
cause of serum hepatitis (human)
R01HL-09I63-13 Control mechanisms in hemostasis
(human)
ROlHL-19255-03 Evaluation of diagnostic clinical
hemorrheology (human)
ROlHL-22607-01 Role of apolipoprotein E in lipoprotein
metabolism (human)
" ROlHL-22618-01 Role of apolipoproteins in
hypertriglyceridemia (human)
BLOOD PROTEINS DISORDERS, HYPERVISCOSITY
SYNDROME
ROlHL-1925503 Evaluation of diagnostic clinical
hemorrheology (human)
R01HL19456-03 Immunoglobulins associated with serum
hyperviscosity (human)
BLOOD PROTEINS DISORDERS,
HYPOPROTEINEMIA
SEE ALSO LIPOPROTEINS BLOOD. HYPOUPOPROTEINEMIA
R01HL12493-10 Biocngineering analysis of microvascular
function (cats, rabbits)
BLOOD PROTEINS DISORDERS CONGENITAL
SEE ALSO BLOOD COAGUUTION DISORDERS
SEE ALSO HEMOPROTEINS, HEMOGLOBINOPATHIES
SEE ALSO METABOLIC DISORDERS INBORN. ACATAUSEMIA
SEE ALSO METABOLIC DISORDERS INBORN.
HEPATOLENTICULAR DEGENERATION
SEE ALSO METABOLIC DISORDERS INBORN.
HYPOLIPOPROTEINEMIAS FAMILIAL
ABETALIPOPROTEINEMIA
SEE ALSO METABOLIC DISORDERS INBORN.
HYPOLIPOPROTEINEMIAS FAMILIAL. TANGIER
DISEASE
ROlHL-02799-22 Abnormal hemoglobins (human)
POlHL-06350-17 0015 Hemostasis research program
project - Genetics (human)
ROlHL-07449-17 Formation and survival of red blood cells
(human)
ROlHL-09163-13 Control mechanisms in hemostasis
(human)
ROlHL-09902-13 Comparative study of coagulation and
vascular disease (animals)
** R01HL-I6872-04 Antihemophilic factor (human)
ROlHL-18834-04 Metal-dependent complex formation in
blood coagulation (human, cattle)
ROlHL-19267-02 Serial comparative study of Von
Willebrand's disease (human)
R01HL-20074-02 Structure and function of amidinafed
human hemoglobin
ROlHL-20092-02 Structural and biological properties of
fibrinogen (human, rabbits)
ROlHL-20142-02 Functional studies of abnormal human
hemoglobins
ROlHL-20161-02 Role of gamma-carboxyglutamic acid in
blood coagulation (human, cattle)
ROlHL-20920-01 Control of hemoglobin synthesis (baboon)
ROlHL-21403-02 Blood clotting kinetics studied by
radioimmunoassay (human)
(contd)
BLO
** R23HL-21730-01 vWagll-A new vWD deficient antigen
(human)
** ROlHL-22505-01 Molecular pathology of fibrinogen and
factor XIII (human, animals)
R23HL-22799-01 Interaction of the complement and
coagulation systems (monkeys)
BLOOD REPLACEMENT PERFUSION (WHOLE
BODY)
SEE BLOOD TREATMENT. WHOLE BODY PERFUSION (BLOOD
REPLACEMENT)
BLOOD RESOURCES - REGISTRIES
SEE BLOOD PRESERVATION, BLOOD BANKS, CENTERS-
RESOURCES-REGISTRIES
BLOOD RHEOLOGY
SEE ALSO BLOOD OSMOTIC PRESSURE
SEE ALSO BLOOD VISCOSITY-VISCOELASTICITY
SEE ALSO CARDIOVASCULAR DISORDERS DIAGNOSIS, BLOOD
FLOW MEASUREMENTS*
SEE ALSO CARDIOVASCULAR FUNCTION. BLOOD CIRCULATION
DYNAMICS (GENERAL)
SEE ALSO CARDIOVASCULAR FUNCTION, BLOOD FLOW
SEE ALSO CARDIOVASCULAR FUNCTION, BLOOD FLOW
IMPEDANCE
SEE ALSO CARDIOVASCULAR FUNCTION. BLOOD FLOW
OSCILUTORY
SEE ALSO CARDIOVASCULAR FUNCTION. VASOMOTION, PULSE
PRESSURE WAVES
SEE ALSO HEART DISORDERS DIAGNOSIS, PICK METHOD*
** ROlHL-1 1901-12 0017 Effects of metabolic surgery on
the hyperlipidemias - Membrane permeability, blood
viscosity, oxygen uptake-Rheology studies (rabbits)
** POlHL-12738-10 0069 Physiologic pharmacology and its
clinical applications - Blood rheology in coronary heart
disease (dogs)
** ROlHL-12839-09 Flow, transport and membrane
phenomena in blood (human)
RClHL-13426-09 Left ventricular bypass for myocardial
infarction (cattle, human)
** POlHL-14388-07 0217 Regulation of the circulation in
pathological states - Fluid mechanics of aortic flow (dogs,
human)
** P60HL15162-07 0019 Comprehensive sickle cell center ■
RBC-Blood rheology in sickle cell anemia and related
disorders (human, animal)
ROIHL- 152 70-06 Local mechanical properties of the aortic
tissue (dogs, pigs)
** R01HL-15722-06 Hemorrheology studies related to in vivo
blood flow (human)
ROlHL-16236-04 Detailed characteristics of coronary blood
flow (horses, dogs, calves)
POlHL-16387-04 0005 The blood vessel and
thrombogenesis • Fluid engineering considerations in
thrombogenesis
** ROlHL-16421-08 Determinants of RBC deformability and
capillary flow (human, mice)
ROIHL- 16580-04 Mathematical models for studying sickle-
cell disease
•* ROlHL-16711-05 RBC and endothelial membrane material
characteristics (human)
•* POlHL-15833-04 0009 Hemoglobin and red cell system in
hemoglobinopathies • Rheological studies of sickled cells
(human)
M POlHL-16851-04 Human red cell membrane in health and
disease
** POlHL-16851-04 0001 Human red cell membrane in
health and disease - Rheology of erythrocyte membrane
(human, amphiuma)
** POlHL-1685104 0003 Human red cell membrane in
health and disease - Modeling membrane mechanics and
blood rheology
POlHL-16851-04 0005 Human red cell membrane in
health and disease - Relation of hemoglobin species to
membrane properties (human)
** POlHL-16851-04 0008 Human red cell membrane in
health and disease - Force balance in red cell interactions
(human)
POlHL-16851-04 0009 Human red cell membrane in
health and disease - Blood cell properties in circulatory
regulation (dogs, rabbits)
ROlHL-16938-05 Effect of physical forces on blood (dogs,
human)
** ROlHL-17408-03 Fresh blood rheology-Relation to
cardiovascular risk (human)
ROlHL-17591-03 Development of electromagnetic
rheoangiography (human, dogs)
ROlHL-17821-03 Cavitation phenomena near prosthetic
devices
M POlHL-18208-04 Center for the study of blood eel!
rheology
P01HL1820804 0004 Center for the study of blood cell
rheology Splenic microcirculation (rats, mice)
** POlHL-18208-04 0005 Center for the study of blood cell
rheology - RBC deformability and capillary flow
interrelations (human, mice)
POlHL-18208-04 0006 Center for the study of blood cell
rheology - Analysis of flow in arterioles and capillaries
(human)
** R01HL18321-03 Fluid shear or magnetic alignment of
blood components (human)
66
' P50HL-18323-04 0042 SCOR hypertension center - Blood
viscosity and blood volume in hypertensive disease
(human, dog)
ROlHL-18584-03 Effects of physical forces on platelets
(human)
ROlHL-18672-03 Dynamic studies of clot structure
formation (human)
* ROlHL-188 18-04 Stereochemical mechanism of sickling of
hemoglobin S (human)
* ROlHL-19255-03 Evaluation of diagnostic clinical
hemorrheology (human)
ROlHL-19993-02 Optical detection of platelet aggregates
(human, baboons)
ROlHL-200 79-02 0003 Thromboresistant material • Blood
surface interactions (human, cattle)
ROlHL-20163-02 Competitive coronary flow in native and
graft vessels (dog)
ROlHL-20177-02 Effects of erythrocyte deformability on
tissue perfusion (rats)
■* ROlHL-20829-02 Fluid mechanics of heart valve
prostheses (dogs, human)
'* P60HL-20985-01 0003 Northern California sickle cell
center - Kinetics of sickling and clinical manifestations in
sickling disorders (human)
ROlHL-21001-0! Protein and thrombus deposition on
vascular grafts
P50HL-2 1006-02 0001 Specialized center of research in
arteriosclerosis - Clinic and core program
POlHL-21016-02 0013 Sickle cell anemia and other
hemoglobinopathies • Microcirculatory response to sickle
cell treated with anti-sickling agents (rats)
** ROlHL-21 188-02 Pulsatory water flux and endothelial cell
desquamation
ROlHL-21270-01 Correlation of arterial hemodynamics and
morphology (human)
** ROlHL-21859-01 Unsteady flow in arterial bifurcations
(human)
** ROlHL-22233-01 Characterization of bio-materials by
elastic property
** ROlHL-22338-01 Platelet adhesion and aggregation in a
flow chamber (human)
ROlHL-22455-01 Platelet concentration in the marginal
layer (dogs, human)
ROlHL-22783-01 Hemodynamic induction of Intimal
fibromuscular lesion
** ROlHL-23267-01 Rheology and kinetics of hemoglobin S
gelation (human)
ROlHL-23899-01 Flow and flexing at blood/biomaterial
interfaces
BLOOD STASIS
ROlHL-01601-30 Blood coagulation and hemorrhagic
disease (horseshoe crabs)
** ROlHL-01648-31 Blood coagulation and hemophilia (dogs,
swine)
** ROIHL 01661-27 Hemostatic mechanisms (human)
** ROlHL-022 54-23 Blood coagulation and hemorrhagic
disease (human, animals)
POlHL-06314-17 0047 Immunologic mechanisms in
cardiovascular disease - Role of intravascular coagulation
(human, animals)
M POlHL-06350-17 Hemostasis research program project
P01HL06350-17 0005 Hemostasis research program
project - Purification of plasma antihemophilic factor
(human)
** P01HL06350-17 0015 Hemostasis research program
project - Genetics (human)
POlHL-06350 17 0018 Hemostasis research program
project - Varients of factors IX (human, cattle)
POlHL-06350-17 0019 Hemostasis research program
project ■ Microcirculation (human, rats, rabbits)
POlHL-06350-17 0020 Hemostasis research program
project - Structure and function of coagulant venom
proteases
** ROlHL-09163-13 Control mechanisms in hemostasis
(human)
** R01HL-09902-13 Comparative study of coagulation and
vascular disease (animals)
ROlHL-10582-12 Thrombosis and hemostasis -Analysis,
methods and standards (human, cattle, venom)
ROIHL 11775-11 Platelet mechanisms in disease (human,
primates)
** ROlHL-11880-10 Physiology and pathology of blood
platelets (human, dogs)
R01HL13160-08 Human thrombin (also cattle)
ROlHL-13198-21 Blood coagulation-Physico-chemical
properties (human, cattle)
POIHL 13262-07 0022 Arterial wall in atherosclerosis -
Mechanisms of platelet prostaglanoin formation
P01HL-I3737-07 0002 Assisted circulation - U-shaped
mechanical auxiliary ventricle (dogs)
** POlHL-13737-07 0026 Assisted circulation - Hemostatic
mechanism (human, dogs)
P50HL14147-08 0017 Specialized center of research in
thrombosis - Core coagulation laboratory (human)
P50HL-142 17-08 0055 Specialized center of research in
thrombosis • Coagulation section-Platelet coagulant activity
(human)
ROlHL-14344-07 Platelet function and adenine nucleotide
metabolism (human)
ROIHL 1459507 Primary disorders of platelet function
(human, rats)
BLO
* R01HL-14697-07 Role of platelet membranes in
hemostasis (human)
ROlHL-14992-07 Mechanism of thrombin action (human)
POlHL-15195-04 0004 Program project in biological
materials - Biological evaluation and surface interaction
studies (dogs)
■* ROlHL-1533506 The nature of the collagen-platelet
Interaction (animals)
ROlHL-15474-06 Structure and function of the
antihemophilic factor (human, cattle)
tfl POIHL- 15486-06 Studies on thrombosis
ROlHL-15491-06 Blood coagulation -Platelet-plasma
protein interaction (human)
VI POlHL-15596-05 Coagulation, fibrinolysis, hemostasis and
hepatitis
ROlHL-15616-04 Platelet membrane proteins in
aggregation (human)
ROIHL- 15690-07 Hydrolytic enzymes of blood in health
and disease (human, animals)
POlHL-16387-04 0005 The blood vessel and
thrombogenesis - Fluid engineering considerations in
thrombogenesis
P01HL16387-04 0006 The blood vessel and
thrombogenesis - Mechanism of delayed vessel graft failure
(dogs, rabbits)
** POlHL-16387-04 0008 The blood vessel and
thrombogenesis - Factor VIII in hemostasis (human,
rabbits)
** P01HL16411-04 0003 Blood systems in coagulation and
vessel disease - Molecular events Involving the late stages
of coagulation (rabbits)
** POlHL-164 11-04 0005 Blood systems in coagulation and
vessel disease • Chemical analysis of serum components
associated with coagulation (human, animal)
ROIHL- 1642 1-08 Determinants of RBC deformability and
capillary flow (human, mice)
P60HL-1726504 0001 Community blood resource center
support - Demonstration and evaluation
** P60HL-17265-04 0007 Community blood resource center
support - Research -Massive transfusion and trauma
(human)
M POlHL-17419-04 Studies on mechanisms of hemostasis
** POlHL-17419-04 0001 Studies on mechanisms of
hemostasis ■ Structure and metabolism of fibrinogen
(human)
** POlHL-17419-04 0003 Studies on mechanisms of
hemostasis • Characterization of fibrinogen (human)
** P01HL17419-04 0006 Studies on mechanisms of
hemostasis Effect of hormones, drugs and other agents
on fibrinogen synthesis (chick)
** POlHL-17419-04 0007 Studies on mechanisms of
hemostasis - Structural analysis of ordered forms of
fibrinogen (human, cattle)
M POlHL-17430-05 Control of coagulation
** POlHL-17430-05 0001 Control of coagulation • Porcine
von Willebrand's disease
P01HL17430 05 0002 Control of coagulation - Isolation
of ristocetin-von Willebrand factor (swine)
POlHL-17430-05 0005 Control of coagulation - The
activation of prothrombin (human, cattle, dogs)
POlHL-1743005 0007 Control of coagulation - Platelet
adhesion, aggregation, ultrastructure in flowing blood
(human, animals)
ROlHL-17462-03 Role of glycosphingolipids in platelet
aggregation (rats, human, dogs)
R01HL17513-04 Role of PF-4 in detecting and promoting
thrombosis (human, primates)
ROlHL-17525-03 Molecular basis of collagen-platelet
interaction (human, rat)
ROlHL-17729-04 Stimulus-response coupling in platelets
(human)
ROlHL-17930-03 Platelet membrane function-Assessment
and application (animals)
** ROlHL-18030-04 The role of contractile proteins in
platelets (human, rabbits)
ROlHL-18321-03 Fluid shear or magnetic alignment of
blood components (human)
ROlHL-18502-03 Enzymatic regulation of platelet function
(human)
M POlHL-18576-03 Thrombosis research program project
POlHL-18576 03 0004 Thrombosis research program
project - Mechanism and control of collagen-platelet
interaction
** POlHL-18576-03 0007 Thrombosis research program
project - Relationships between coagulability and
thrombosis (human, animals)
** P01HL18576-03 0009 Thrombosis research program
project ■ Biology of factor VII (human, rabbits, cattle)
POlHL-18576-03 0012 Thrombosis research program
project - Synthetic anticoagulant and thrombolytic agents
(dogs)
** R01HL1858603 Role of platelet lipids in hemostasis and
thrombosis (human)
ROlHL-18650-03 Platelet collagen interaction (human)
R01HL1881503 Surgical vascular disorders (human.
dogs)
POlHL-18827-02 0007 Platelet vessel wall interactions in
thrombogenesis ■ Biochemistry and role factor V in
thrombogenesis (human, cattle)
P50HL18828-03 0001 Specialized center of research in
thrombosis - Membrane biology and hemostasis (human)
(contd)
'Eidudes routine methodotogy OR covers only general projects which preclude
"Oriented significantly to above subject.
Indexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
•lO
67
PbOHl 18828 03 000? Sptclaliitd centitr ol tmaacch in
thcomboils Endothelial call biology (human, |uin«a pig)
RUIHl 18834 04 Mttaldapandent complei loimation in
blood coagulation (human, cattle)
ROIHL I893S03 Platelets. Iibnnogen. soluble libiin
interaction (human)
ROIHI 192;003 Ellects ol eiythiopoiesis on plilelels and
hemostasis (rats)
ROIHI 19282 03 Regulation ol the activation of human
ladoi X
ROIHL 1999602 Role ol membrane proteins in platelet
(unction (human, rabbits)
ROIHI 20014 02 Radioimmunoassay of hyper and
hypocoagulable states (rabbits)
ROIHL 20106 02 Coupling ol platelet conliactile proteins
to fibrin (human)
ROIHI 20?87 02 Thromboxanes and prostaglandins"
Biochemical pharmacology (rabbits, human)
ROIHL 20846 02 Purification of bovine plasminogen
proactivator
ROIHL 20956 02 Early events following stimulation of
human platelets
POIHL 21016 02 0013 Sickl« cell anemia and othei
hemoglobinopathies Microcirculalory response to sicKle
cell treated with anti sicKling agents (rats)
R01HL2111301
(cattle)
Physiologic pharmacology and its
Olood theology in coronary hearl
Control mechanisms in coagulation
Ion and Shydroxytryptamine transport by
Structure of factor VlllVon Willebrand
ROlHL-21217-01
platelets
R01HL2137901
protein (human)
R01HL2146002 Lipoproteins, hemostasis and
atherosclerosis (human, rabbits)
ROIHL 2148701 Molecular characterization of
Glanzmann's thrombasthenia (human)
R23HL-21490-02 Studies of enzymes in human platelet
membranes
ROlHl-21988 01
chemotaxis
ROlHL-22289-01
(rabbits)
ROlHl-22355-01
Biochemistry of human platelet
Endothelial cell mediated fibrinolysis
Purification, structure and function of
factor VIII (human)
ROlHL-2250201 ' Role of phosphoinositides in human
platelet secretion
ROlHL-22583-02 Ultrastructural study of endothelium in
thrombosis (human)
POlHL-2260201 0001 Pathophysiology of the
endothelium • Platelet-endothelial interactions in vitro
(human, cattle)
ROlHL-22671-01 Removal of senescent and stored human
red cells
ROlHL-2295501 inetics of prothrombin activation
BLOOD SUBSTITUTES
** ROlHL-1552006 Total blood replacement by fluorocarbons
and polyols (rats)
** R01HLI6643-02 Fluorocarbon emulsions as artificial
blood (animals)
ROlHL-17705-04 Kallikrein-kinin system in hypertension
(human, rats, dogs)
** ROlHL-17794-03 Chelating agents as blood substitutes
** ROlHL-17844-04 Artificial blood substitutes-02-binding
iron chelates (human, mammals)
** ROlHL-23 120-01 Chelating agents as blood substitutes
BLOOD SUBSTITUTES, PLASMA SUBSTITUTES
POIHLI 1678-11 0034 Cardiovascular dynamics and their
control - Renal function curves in intact dogs
ROlHL-14693-07 Survival value of physiological responses
to hypoxia (dogs)
R01H1.-18010-04 Capillary transport of large molecules
(dogs, sheep)
BLOOD SUGAR
SEE CARBOHYDRATE BALANCE, BLOOO SUGAR
BLOOD SUPPLY
SEE CARDIOVASCULAR SYSTEM. BLOOD SUPPLY
BLOOO SUPPLY OF NEOPLASMS
SEE NEOPLASMS VASCULAR SUPPLY
BLOOD (HEMATOLOGIC) TESTS*
ROIHL 10567 12 Erythropoietin-Immunoassay and
characterization (dogs) '
** P50HL-14230-07 0097 A/S SCOR -Lipids, atherosclerosis
and thrombosis - Studies of circulating platelet aggregates
(human)
P60HL-15158-07 0008 Comprehensive sickle cell center ■
Core laboratory of the center
P60HL- 17265-04 0001 Community blood resource center
support - Demonstration and evaluation
** ROlHL-18256-01 Optical properties of platelets and
erythrocytes (rabbits, dogs, human)
BLOOD (HEMATOLOGIC) TESTS, BLOOD CELL
COUNT*
ROlHl-03181-21 0025 Hemodynamics as applied to
surgical problems - Vascular stenosis (dogs)
ROlHL-11152-12 Vascular physiology (human, cats, dogs)
ROlHL-12530-10 Emphysema-Respiratory function in
diseas* (human, dogs, rats)
** POIHI 12/38 10 0069
ilinical applications
disease (dogs)
POIHL 149850/ 0013 Adaptation to hypoxia Chronic
mountain sickness (man)
ROIHL 1504/ 06 Digital computer analysis ol the
electrocardiogram (human)
P60HL 15169 05 0019 Support for center for sicklo cell
disease Central screening and reference laboratory
ROIHL 15520 06 Total blood replacement by fluorocarbons
and polyols (rats)
POIHL 16851 04 0009 Human red cell membrane in
health and disease Blood cell properties in circulatory
regulation (dogs, rabbits)
POIHL 18208 04 0003 Center lor the study of blood cell
rheology Bone marrow microcirculation (rats, mice)
ROIHL 18321 03 Fluid shear or magnetic alignment of
blood components (human)
P50HL 19153 02 0005 SCOR Pulmonary edemas Eitology,
pathogenesis Lung vascular permeability measured by
indicator dilution methods (sheep)
ROIHL 19203 03 Surgical approach to congenital heart
diseases (dogs, primates)
ROIHL 19270 03 Effects of erythropoiesis on platelets and
hemostasis (rats)
ROIHL 19993 02 Optical detection of platelet aggregates
(human, baboons)
POIHL 22163-01 0002 Surface thrombogenesis
Mechanisms and prevention Laser scattering detection ol
microemboli in blood How (baboons)
BLOOD (HEMATOLOGIC) TESTS, BLOOD
SEDIMENTATION, ERYTHROCYTE*
R01HL18321 03 Fluid shear or magnetic alignment ol
blood components (human)
BLOOD (HEAAATOLOGIC) TESTS, OSMOTIC
FRAGILITY*
R01HL18660-03 Neurotransmitter receptors in human
erythrocytes
ROlHL-20882-02 Interactions ol plasma lipoproteins with
erythrocytes (Rhesus, human)
BLOOD TOXICOLOGY
SEE ALSO IMMUNOLOGICAL TESTS AND IMMUNOASSAY,
HEMAGGLUTINATION*
NOlHB-22919-08 Hemoglobin carbamylation in the
treatment of sickle cell anemia (human, dogs)
NOIHB 22922 08 Develop effective therapy for sickle cell
disease (human, dogs)
POlHL-09011-15 0022 A research and resource program
in blood - Ciyopreservation of blood components (human)
R01HL23654-01 Selected topics on blood transfusion
(rabbits, human)
NOlHV-32950-08 Blood compatible poly-electrolytes
NOlHV-32953-10 Materials compatible with blood (dogs)
BLOOO TOXICOLOGY, BACTEREMIA-SEPTICEMIA
" ROlHL-02363-20 Kinetics of water and electrolytes in
shock (dogs, rats)
ROlHL-03181-21 0029 Hemodynamics as applied to
surgical problems - Indocyanine green clearance for
estimation of hepatic blood flow (human)
POlHL-06350-17 0019 Hemostasis research program
project - Microcirculation (human, rats, rabbits)
ROlHL-08659-14 Myocardial performance and metabolism
in the newborn (sheep)
M POlHL-08682-15 Regulation of the cardiovascular system
** POlHL-08682-15 0019 Regulation of the cardiovascular
system - Hepatic immunophysiology and host-defense in
shock (rat, dog, human)
** POlHL-08682-15 0020 Regulation of the cardiovascular
system - Hepatic metabolic basis of shock (rat)
** POlHL-08682-15 0021 Regulation of the cardiovascular
system - Hypoglycemia in pathogenesis of shock (dog)
** P01HL-08899-I4 0010 Tolerance to respiratory gases in
health and disease • High oxygen pressure in septic shock
(human)
** ROlHL-12421-10 Pathophysiology of circulatory shock
(dogs, baboons)
P50HL-151 62-07 0021 Comprehensive sickle cell center -
Pneumococcal vaccine in sickle cell disease (children)
P60HL15169-05 0009 Support for center for sickle cell
disease - Infections in sickle cell anemia (human)
ROlHL-15593-05 Prolonged extracorporeal cardiopulmonary
support (rats, sheep, rabbits)
P01HL164 11-04 0004 Blood systems in coagulation and
vessel disease - Platelets reactions in vascular injury
(human, animals)
ROlHL-16642-05 Biochemistry and pathophysiology of
plasma kallikrein (human, animals)
POlHL-16769-05 0002 Pathobiologic and host defense
reactions in the lung - Pathogenesis of complement
dependent injury to the lungs (rabbits)
** ROlHL-17479-04 Blood storage-The production of
cardiotoxic material (dogs, human, swine)
** ROlHL-17751-03 Experimental endocarditis (rabbits)
•* P01HL-17812-04 0007 Thrombosis and plasma proteins ■
Blood components-Response to endotoxin (dogs, baboons)
R01HL19030-03 Tissue protection during circulatory
interruption (dogs)
•Excludes n)utine melhodotogy OR covers only general projects which preclude indexing
"Wented significantly to above subject.
at the specific level.
M Grant has subprojects descnbing specific research aspects
See Appendix for investigator's name and grant number
MO
P50m 19151 07 0001 SCOR Pulmonary cdamai Filoloty.
pathu|tn«ii« Protlaflandins and lh< lung circulation
(sheep)
P50HI 19153 02 0007 StOR Pulmonary tdtmai (itolofy.
palhogenesis lung lluid dynamic* Clattiol mediatoit
and their inhibilor\ (sheep)
" P50HI 19153 07 0001 SCOR Pulmonary edemai Fitoloiy.
pathogenesis Possible inhibitors ol mediator rtleai* and
pulmonary vascular response (sheep)
ROIHI 19374 03 Pharmacology ol kinini in cardiovascular
disease (rats, rabbits)
ROIHI 196/3 03 Surgical aspects of shock and hypoxia
(dogs, monkeys, rals)
ROIHL 19/75 03 Complement inducwl pulmonary injury
(dogs, rabbits, sheep)
*• ROIHL 1997/02 Genesis of circulatory shock by
pancreatic peptides (cats, dogs)
ROIHI 203/1 02 Intravascular redistribution of blood
volume (dogs)
ROIHL 20787 02 Thromboxanes and prostaglandins
Biochemical pharmacology (rabbits, human)
R73HL21116 02 Mechanisms of membrane and tissue
damage in lung (dogs, rabbits)
ROIHL 2117202 Regional oxygen consumption of heart
and other organs (animals)
ROIHL 2243502 Pulmonary alveolar capillary permeability
characteristic (dogs)
ROIHL 22520 01 Pulmonary vascular response to group B
Streptococci (human, mammals)
** R01HL2311401 Control of platelet aggregation in shock
(dogs, rabbits)
R01HL2361801 Substrate metabolism in isolated
myocytes in shock (dogs, rats, guinea pigs)
BLOOD TOXICOLOGY, HEMOLYSINS
SEE ALSO BLOOD CELLS. ERYTHROCYTES, HEMOLYSIS
SEE ALSO PHOSPHOLIPIDS. PHOSPHOGLYCERIDES.
LYSOLECITHIN
ROIHL 19532-01 Oxygen toxicity in the red cell (human)
BLOOD TOXICOLOGY, HEMOTOXINS
** ROlHL-17479-04 Blood storage-The production ol
cardiotoxic material (dogs, human, swine)
BLOOD TRANSFUSION
SEE ALSO BLOOO GROUP INCOMPATIBILITY
SEE ALSO BLOOD SUBSTITUTES
SEE ALSO CARDIOVASCULAR SURGERY, EjaRACORPOREAL
CIRCULATION, CROSS CIRCULATION
NOlHB-62963-03 International bone marrow transplant
registry
NOlHB-62964-03 International bone marrow transplant
registry
ROlHL-0869615 0011 Orthotopic heart transplantation -
Transplantation immunology-lmmunodepressive factor
(human, dogs)
POlHL-09011-15 0017 A research and resource program
in blood - Operations research laboratory
P01HL-090I1 15 0022 A research and resource program
in blood - Cryopreservation of blood components (human)
ROlHL-10582-12 Thrombosis and hemostasis-Analysis,
methods and standards (human, cattle, venom)
** P01Hm310-12 0095 Mechanisms of cardiovascular
disease - Blood and transfusion disorders (human, rats,
monkeys)
P60HL 15158-07 0004 Comprehensive sickle cell center -
Expression of abnormal hemoglobin synthesis in the
neonate and young child
P60HL-15158-07 0012 Comprehensive sickle cell center -
Clinical seivices-Pediatric patients
** P50HL-15160-07 0011 Center for sickle cell disease -
Study of human sickle cells in an animal model (rats)
** P60HL-15160 07 0014 Center for sickle cell disease -
Replacement therapy of opsonin deficiency in sickle cell
anemia (children)
P60HL-16008-06 0014 Wayne State University
comprehensive sickle cell center - Zinc and red blood cell
metabolism in sickle cell anemia (rats, human)
ROlHL-16626-05 Studies of antibodies to antihemophilic
factors (human, rabbits)
** ROlHL-16931-04 Red cell storage and transfusion
(human, animals)
M P60HL-1 7265-04 Community blood resource center support
P60HL-17265-04 0001 Community blood resource center
support - Demonstration and evaluation
P60HL-17265-04 0007 Community blood resource center
support ■ Research-Massive translusion and trauma
(human)
P60HL 17265-04 0008 Community blood resource center
support - Research-Blood genetic markers as biological
probes (human)
POlHL-17430-05 0001 Control of coagulation - Porcine
von Willebrand's disease
ROlHL-17479-04 Blood storage-The production of
cardiotoxic material (dogs, human, swine)
POlHL-18646-03 0004 Studies basic to heart
transplantation - Presensitization -Detection, incidence and
clinical significance
ROlHL-19898-03 Desferrioxamine therapy in thalassemia
(dogs. rats, children)
** ROlHL-19946-03 Reduction of iron overload in
thalassemia (children, rabbits, dogs, monkeys)
(contd)
BLO
** ROlHL-19961-03 Management of hemosiderosis in
thalassemia (childrenn adults)
** R01HL19993-02 Optical detection of platelet aggregates
(human, baboons)
ROlHL-20000-03 Iron overload in homozygous beta
thalassemia (human)
ROlHL-20016-03 Chelator development for thalassemia
(human, mice, rats, dogs, monkeys)
ROlHL-20141-02 Biochemical approaches to management
of iron overload (human, sheep, dogs)
P60HL-20985-01 0007 Northern California sickle cell
center - Immunohematologic abnormalities in sickle cell
anemia (human)
ROlHL-22671-01 Removal of senescent and stored human
red cells
** ROlHL-22838-01 Post-transfusion hepatitis in newborn
children
P60HL-2328201 0002 Comprehensive hospital/community
sickle cell center - Clinical evaluation of alternate
pathaway of compliment activation
** ROlHL-23654-01 Selected topics on blood transfusion
(rabbits, human)
BLOOD TRANSFUSION, AUTOTRANSFUSION
ROlHL-16656-06 Left ventricular function in exercise
(dogs)
ROlHL-18815-03 Surgical vascular disorders (human,
dogs)
ROlHL-207 16-02 Freezing and electromagnetic thawing of
platelets (rats)
** ROlHL-22005-01 Intermittent retroperfusion of ischemic
myocardium (dogs)
BLOOD TRANSFUSION, BLOOD DONORS
NOlHB-62970-02 Collection, function and transfusion of
granulocytes
NOlHB-6297305 Collection, function and transfusion of
granulocytes
P01HL-0901M5 0017 A research and resource program
in blood ■ Operations research laboratory
** POlHL-09011-15 0018 A research and resource program
in blood ■ Hepatitis B in normal populations -Epidemiology,
risk factors and transmission
POlHL-09011-15 0020 A research and resource program
in blood - Passive immunization in the prevention of
transmission of hepatitis B (human)
P60HL15996-06 0008 Cincinnati comprehensive sickle
cell center ■ Patient care (children, adults)
** P60HL-17265-04 0001 Community blood resource center
support ■ Demonstration and evaluation
ROlHL-23654-01 Selected topics on blood transfusion
(rabbits, human)
BLOOD TRANSFUSION, EXCHANGE
SEE ALSO BLOOD TREATMENT, WHOLE BODY PERFUSION
(BLOOD REPLACEMENT)
** P50HL-15061-07 0013 Response of lung to injury ■
Exchange transfusion in infants with respiratory distress
syndrome (human, sheep)
R01HL15215-06 Role of complement in intravascular
coagulation (rabbits, mice)
** P60HL-16C0505 0021 Comprehensive sickle cell center -
Management of pregnancy in sickle cell anemia (human)
P60HL-16005-05 0022 Comprehensive sickle cell center -
Regulation of erythropoiesis in patients with sickle cell
anemia
POlHL-19737-02 0006 Cellular and molecular aspects of
respiratory physiology - Tissue oxygenation and
mitochondrial respiratory activity (sheep)
ROlHL-20337-02 Thromboembolic diseases (human)
BLOOD TRANSFUSION, LEUKOCYTE
TRANSFUSION
** NOlHB-62970-02 Collection, function and transfusion of
granulocytes
** NOlHB-62971-03 Collection, function and transfusion of
granulocytes
** NOlHB-62972-05 Collection, function and transfusion of
granulocytes
" NOlHB-6297305 Collection, function and transfusion of
granulocytes
** P60HL-17265-04 0009 Community blood resource center
support Research -Developing granulocyte transfusion
therapy (human, rabbit)
R23HL-21997-01 Pulmonary immunopathology in the
compromised host (guinea pigs)
BLOOD TRANSFUSION, PLATELET TRANSFUSION
P01HL1131012 0095 Mechanisms of cardiovascular
disease - Blood and transfusion disorders (human, rats,
monkeys)
ROlHL-13629-08 Hemorrhagic diseases (human)
R01HL14637-05 Thrombopoietin -Immunoassay and
characterization (mice)
" P60HL1 7265-04 0006 Community blood resource center
support • Research -Evaluation of platelet transfusions
(human, dog)
ROlHL-207 16-02 Freezing and electromagnetic thawing of
platelets (rats)
ROlHL-2078802 Preservation of human platelets for
transfusion
ROlHL-20818-02 Platelet storage at 22 degrees C
(human)
68
** ROlHL-2085602 Platelet transfusions -Usage and
complications (human)
BLOOD TREATMENT, BLOOD FILTERS
R01HL12839-09 Flow, transport and membrane
phenomena in blood (human)
P60HL17265-04 0009 Community blood resource center
support - Research -Developing granulocyte transfusion
therapy (human, rabbit)
ROlHL-19993-02 Optical detection of platelet aggregates
(human, baboons)
** ROlHL-205 54-02 Memory-alloy-filters for venous emboli
(dogs)
BLOOD TREATMENT, BLOOD FILTERS, VENA
CAVA FILTERS
** POlHL-11414-11 0027 Thrombosis and atherosclerosis
program ■ Thermal memory wire filter to prevent pulmonary
embolism (human, dogs)
BLOOD TREATMENT, HEMODIALYSIS
SEE ALSO KIDNEY PROSTHESIS, ARTIFICIAL KIDNEY
** NOlHB-229 19-08 Hemoglobin carbamylation in the
treatment of sickle cell anemia (human, dogs)
** NOlHB-22922-08 Develop effective therapy for sickle cell
disease (human, dogs)
** NOlHB-62962-02 Red cell distributions in cyanate-treated
blood (human, sheep)
R01HL00340-29 Electrolyte disturbance in cardio-renal
disease (human, dogs, rats)
** POlHL-06370-17 0013 Cardiopulmonary and renal
pathology research center - Morphologic analysis of
vascular prosthesis (human, dogs)
POlHL-0683517 0064 Cardiovascular disease - Studies
in atherosclerosis (human, animals)
P01HL0901M5 0020 A research and resource program
in blood - Passive immunization in the prevention of
transmission of hepatitis B (human)
POlHL-090 11-15 0023 A research and resource program
in blood ■ Evaluation of hepatitis B vaccine in endemic
settings (human)
P01HL1131012 0084 Mechanisms of cardiovascular
disease ■ Evaluation of cardiac function in chronic renal
failure (human)
ROlHL-12839-09 Flow, transport and membrane
phenomena in blood (human)
ROlHL-14092-07 Homeostatic regulation of plasma choline
(rats, dogs, chickens)
R01HL14133-08 Intrarenal regulation of sodium
reabsorption (dogs, hamsters, rats)
R01HL1512405 Genesis of hypertension in renal disease
(human, dogs)
** R01HL1566806 Extracorporeal respiratory gas exchange-
A new approach (dogs)
R01HL162 19-05 Mechanisms of atherogenesis in chronic
uremia (human, rats)
ROlHL-18923-02 Steroid-induced hyperlipidemia and
hypertension (human, rats)
ROlHL-19428-03 Role of angiotensin sensitivity in renin
release (human)
** ROlHL-20141-02 Biochemical approaches to management
of iron overload (human, sheep, dogs)
ROlHL-201 77-02 Effects of erythrocyte deformability on
tissue perfusion (rats)
ROlHL-2262701 An inhibitor of platelet adhesion to
artificial organs (human)
ROIHL 23899-01 Flow and flexing at blood/biomaterial
interfaces
BLOOD TREATMENT, LEUKAPHERESIS
P60HL17265-04 0009 Community blood resource center
support - Research -Developing granulocyte transfusion
therapy (human, rabbit)
BLOOD TREATMENT, PLASMAPHERESIS
POlHL-1141411 0033 Thrombosis and atherosclerosis
program - Human coumarin-induced prothrombin
P01HL17430-05 0001 Control of coagulation - Porcine
von Willebrand's disease
POlHL-1743005 0002 Control of coagulation - Isolation
of ristocetin-von Willcbrand factor (swine)
BLOOD TREATMENT, PLATELETPHERESIS
P60HL-17265-04 0006 Community blood resource center
support ■ Research-Evaluation of platelet transfusions
(human, dog)
BLOOD TREATMENT, WHOLE BODY PERFUSION
(BLOOD REPLACEMENT)
** R01HL-I5520-06 Total blood replacement by fluorocarbons
and polyols (rats)
** R01HL17844-04 Artificial blood substitutes -02-binding
iron chelates (human, mammals)
BLOOD TYPES
SEE BLOOD GROUPS
BLOOD VESSELS
SEE CARDIOVASCULAR SYSTEM, BLOOD VESSELS (GENERAL)
BLOOD VESSELS DISORDERS (GENERAL)
SEE CARDIOVASCULAR DISORDERS, VASCULAR DISORDERS
(GENERAL)
BLO
BLOOD VESSELS NEOPLASMS
SEE NEOPLASMS OF CARDIOVASCULAR SYSTEM
BLOOD VESSELS PRESERVATION
SEE CARDIOVASCULAR TISSUE PRESERVATION
BLOOD VESSELS PROSTHESIS
SEE CARDIOVASCUUR PROSTHESIS, BLOOD VESSELS
PROSTHESIS
BLOOD VESSELS RESTORATION
SEE CARDIOVASCULAR SURGERY, BLOOD VESSELS
RESTORATION
BLOOD VESSELS SHUNTS ARTERIOVENOUS
ABNORMAL
SEE CARDIOVASCULAR DISORDERS, ARTERIOVENOUS SHUNTS
ABNORMAL
BLOOD VESSELS SHUNTS ARTERIOVENOUS
NORMAL
SEE CARDIOVASCUUR SYSTEM. ARTERIOVENOUS
ANASTOMOSIS NORMAL
BLOOD VESSELS SHUNTS COLLATERAL
CIRCULATION NORMAL
SEE CARDIOVASCULAR SYSTEM, BLOOD SUPPLY, COLUTERAL
CIRCUUTION
BLOOD VESSELS SHUNTS DUCTUS ARTERIOSUS
EMBRYONIC
SEE CARDIOVASCULAR SYSTEM, DUCTUS ARTERIOSUS
EMBRYONIC
BLOOD VESSELS SHUNTS SURGICAL
SEE CARDIOVASCUUR SURGERY, CARDIOVASCUUR SHUNTS
BLOOD VESSELS TRANSPLANTATION
SEE CARDIOVASCUUR TRANSPUNTATION, BLOOD VESSELS
TRANSPUNTATION
BLOOD VISCOSITY-VISCOELASTICITY
SEE ALSO BLOOD PROTEINS DISORDERS, HYPERVISCOSITY
SYNDROME
*• ROlHL-03181-21 0025 Hemodynamics as applied to
surgical problems - Vascular stenosis (dogs)
ROlHL-08977-14 Quantitation of flow and solute flux in
microvessels (cats, rats)
ROlHL-1190112 0017 Effects of metabolic surgery on
the hyperlipidemias • Membrane permeability, blood
viscosity, oxygen uptake -Rheology studies (rabbits)
ROlHL-12256-15 Polymerization of sickle-cell hemoglobin
(human)
POlHL-12738-10 0069 Physiologic pharmacology and its
clinical applications ■ Blood rheology in coronary heart
disease (dogs)
ROlHL-12775-08 Cerebral microcirculation (mice)
P60HL 15157-07 0011 Comprehensive center for sickle
cell disease ■ Development of specific anti-sickling
compound (human)
P60HL-15162-07 0019 Comprehensive sickle cell center ■
RBC-Blood rheology in sickle cell anemia and related
disorders (human, animal)
** P60HL1599606 0010 Cincinnati comprehensive sickle
cell center - Whole blood viscosity in sickle cell anemia
(human)
P01HL16387-04 0005 The blood vessel and
thrombogenesis ■ Fluid engineering considerations in
thrombogenesis
ROlHL-1642108 Determinants of RBC deformability and
capillary flow (human, mice)
POlHL-1683304 0008 Hemoglobin and red cell system in
hemoglobinopathies - Membrane associated phenomena in
SS disease
POlHL-16833-04 0009 Hemoglobin and red cell system in
hemoglobinopathies - Rheological studies of sickled cells
(human)
M P01HL16851-04 Human red cell membrane in health and
disease
•* POlHL-16851-04 0001 Human red cell membrane in
health and disease - Rheology of erythrocyte membrane
(human, amphiuma)
POlHL-1685104 0003 Human red cell membrane in
health and disease ■ Modeling membrane mechanics and
blood rheology
ROlHL-16927-05 Structure and function of normal and
abnormal hemoglobin (human)
R01HL16938-05 Effect of physical forces on blood (dogs,
human)
R01HL17408-03 Fresh blood rheology-Relation to
cardiovascular risk (human)
POlHL-1820804 0004 Center for the study of blood cell
rheology - Splenic microcirculation (rats, mice)
POlHL-18208-04 0005 Center for the study of blood cell
rheology RBC deformability and capillary flow
interrelations (human, mice)
POlHL-18208-04 0006 Center for the study of blood cell
rheology - Analysis of flow m arterioles and capillaries
(human)
** P50HL18323-04 0042 SCOR hypertension center ■ Blood
viscosity and blood volume in hypertensive disease
(human, dog)
R01HL18467 03 Fingertip blood flow in normals and
Raynaud's disease (human)
(contd)
•Ettludes iDutine nethodotogy OR covers only general projects which preclude
"Oiiented significanthf to above subject.
ndexing at the specific level.
M Giant has subproieds describing specific research aspects.
See Appendix tor Investigatot's name and grant number.
Characterisation of bio materials by
■lO
" ROIHL I8i84 03 EflKts of physlcil force] on plotolits
(human)
ROIHL 18672 03 Dynamic studlts ot clot structure
formation (human)
ROIHL 19203 03 Surgical approach to conienilal heart
diseasts (dO|S. primates)
ROIHL 192S5 03 Evaluation ol diagnostic clinical
htmorrhaology (human)
ROIHL 20106 02 Coupling ol platelet contiactile proteins
to fibrin (human)
P60HL 20985 01 0003 Northern Calilomia sickle cell
center Kinetics ol sicKlmg and clinical manileslations in
sickling disorders (human)
POIHL 21016 02 0013 Sickle cell anemia and othei
hemoglobinopathies Microcirculatory response to sickle
cell treated with antisickling agents (rats)
ROIHL'22223-OI The cardio pulmonary {unction (dogs.
models)
** R01HL2223301
elastic property
ROIHL 224SS'01 Platelet concentration in the marginal
layer (dogs, human)
*• ROlHL-2326701 Rheology and kinetics of hemoglobin S
gelation (human)
" ROlHL-2390001 Mechanical measurement ol cell
membrane viscosity (human)
BIOOD VOLUME
SEE CARDIOVASCULAR FUNCTION. BLOOD VOLUME
BLOODLETTING
POIHL 1131012 0095 Mechanisms of cardiovascular
disease Blood and transfusion disorders (human, rats,
monkeys)
BLOOM'S SYNDROME
SEE GENETIC DISORDERS. BLOOMS SYNDROME
BODY CAVITIES, DIAPHRAGM
SEE ALSO BODY CAVITY DISORDERS, DIAPHRAGMATIC HERNIA
SEE ALSO NERVOUS SYSTEM, SPINAL NERVES. PHRENIC
NERVE
** ROlHL-04651-19 Remote stimulation by radio-frequency
transmission (dogs, human)
POlHL-14580-07 0003 Program project in respiratory
mechanics - Chest wall mechanics and respiratory control
(human, dogs)
R01HL1771504 Respiratory muscle afferents in
respiratory control (cats)
ROlHL-18007-05 Neural mechanisms controling motor act
of breathing (cats, human)
POlHL-21584-02 0004 Respiratory mechanics in normal
and abnormal states - Effects of anesthesia on respiratory
mechanics (dogs)
** R13HL-22525-0I International symposium on the
diaphragm (Virginia)
** ROlHL-22844-01 Phrenic nerve pacing-Noninvasive
diaphragm analysis (human, dogs)
" R0IHL-23985-0I Role of the diaphragm in regional lung
mechanics (dogs)
BODY CAVITIES, MEDIASTINUM
POlHL-21584-02 0004 Respiratory mechanics in normal
and abnormal states - Effects of anesthesia on respiratory
mechanics (dogs)
BODY CAVITIES, MESENTERY
ROlHL-06736-18 Biogenic-mechanical factors in
microcirculation (rats, gerbils)
ROlHL-10881-13 Structure and function of
microcirculation (hamsters, rats, cats, dogs)
R01HL-1249310 Bioengineering analysis of microvascular
function (cats, rabbits)
ROlHL-13437-09 Physical and mechanical parameters in
the microcirculation (animals)
** P01HL-I7421-05 0003 Regulation and exchange in the
microcirculation - Transcapillary fluid exchange in rat
intestinal muscle, mucosa, and mesentery
P01HL1742105 0004 Regulation and exchange in the
microcirculation - Localization of flow regulation in the
microcirculation (cats, human)
POlHL-17871-04 0009 Kidney, sodium, cardiac output,
arterioles and hypertension • Kidney, sodium, cardiac
output, arterioles and hypertension
ROlHL-18831-03 Microscopy of spontaneously hypertensive
arterial lesion (rats)
** POlHL-20581-01 0004 Vascular neuroeffector
mechanisms in health and disease - Neuroeffector
characteristics of mesenteric and pulmonary blood vessels
(rabbits)
R01HL-2I351-02 Renal and vascular control by
sympathetic ganglia (animals)
** ROlHL-22561-01 Hormonal control of mesenteric
circulation (cats)
BODY CAVITIES, OMENTUM
ROlHL-12493-10 Bioengineering analysis of microvascular
function (cats, rabbits)
BODY CAVITIES, PERITONEUM
R23HL-21 134-02 Immune function and fibrogenesis in
silicosis (guinea pigs)
BODY CAVITIES, PLEURAL CAVITY
SEE ALSO BODY REGIONS, THORAX
ROIHI 14495 05
(mnminnM
69
Solid jind tliudural mechanics ol lung)
Dietary effects on cholesterol metabolism
Effect of exercise upon the hypertensive
BODY CAVITY DISORDERS, DIAPHRAGMATIC
HERNIA
ROIMI 15526 05 Respiratory mechanics in children
ROIHI 19839 09 Factors in youth predisposing to chronic
diseases (lormoi college students)
BODY CAVITY DISORDERS, PERITONEAL
ROIHL 131/2 10 Post trauma lung mechanics and fluid
exchange (human, dogs, monkeys)
BODY CAVITY DISORDERS, PERITONEAL
EFFUSIONS, ASCITES
ROIHI 18020 04 Splanchnic hemodynamics in man
ROIHL 22051 01 Role of angiotensin II in vasopressin
release (human)
BODY CAVITY DISORDERS, PLEURAL
POIHL 06312 17 0050 Surgical cardioloey Prevention ol
pericardial and pleural adhesions by silicone oil (dogs)
ROIHL 13172 10 Post trauma lung mechanics and fluid
exchange (human, dogs, monkeys)
POIHL 21584 02 0002 Respiratory mechanics in normal
and abnormal states Lung mechanics Regional
delormation and ventilation (dogs)
BODY CAVITY DISORDERS, PLEURAL,
PNEUMOTHORAX (GENERAL)
SEE ALSO RESPIRATORY DISORDERS, ATELECTASIS
ROIHL 13172 10 Post-trauma lung mechanics and fluid
exchange (human, dogs, monkeys)
** R23HL-21050 02 Mechanisms of re-expansion pulmonary
edema (rabbits)
BODY CAVITY DISORDERS, PLEURAL EFFUSIONS
** POlHL-06285-18 0145 Cardiovascular-respiratory
physiology and biochemistry - Pulmonary, pleural and
systemic microcirculation (animals)
** ROlHL-19678-01 Quantification of intrathoracic fluid by
impedance (human, dogs)
POIHL 19717-02 0043 Response of the lung to injury -
Asbestosis as a model of usual interstitial pneumonia
(human)
R23HL-21050-02 Mechanisms of re-expansion pulmonary
edema (rabbits)
BODY COMPOSITION
ROlHL-03299-21
(rats, rabbits)
R01HL-21578-01
adolescent
BODY FLUIDS (AND RELATED SUBSTANCES)
SEE ALSO BIOLOGICAL TRANSPORT, FLUID EXCHANGE AND
TRANSPORT
SEE ALSO BLOOD AND RE SYSTEM, BLOOD*
SEE ALSO BLOOD AND RE SYSTEM, LYMPH
SEE ALSO CELL FLUIDS
SEE ALSO EAR, LABYRINTHINE FLUIDS
SEE ALSO EYE, AQUEOUS HUMOR
SEE ALSO NERVOUS SYSTEM CENTRAL, CEREBROSPINAL
FLUID
SEE ALSO URINE*
POlHL-06835 17 0059 Cardiovascular disease -
Metyrapone-induced hypertension in dog
** POlHL-082 14-15 0047 Chemical and biological properties
of lipids - High resolution liquid chromatography for the
analysis of biological substances
R01HL-I0942-09 Study of genetic hypertension in rats
** POlHL-11678-11 0020 Cardiovascular dynamics and their
control - Circulatory and pulmonary fluid dynamics during
pulmonary edema
POlHL-11678-11 0064 Cardiovascular dynamics and their
control - Renal medulla -Control of renal hemodynamics,
electrolyte excretion (dogs)
** POlHL-11678-11 0065 Cardiovascular dynamics and their
control - Body fluid volumes in the genesis of hypertension
(dogs)
POlHL-11678-11 0068 Cardiovascular dynamics and their
control - Basic hemodynamics (rats, dogs)
ROlHL-12990-09 Control of antidiuretic hormone secretion
and metabolism (dogs, rats, rabbits)
ROlHL-131 72-10 Post-trauma lung mechanics and fluid
exchange (human, dogs, monkeys)
ROIHL-13901-08 Ontogeny, ultrastructure, function in
lymphatic system (birds, fish, mammals)
ROlHL-16855-03 Cavitation in biological systems
(microorganisms, animals)
R01HL-19065-02 Molecular oxygen in biological fluids
ROlHL-19678-01 Quantification of intrathoracic fluid by
impedance (human, dogs)
ROlHL-19825-02 Renin-volume interactions in coarctation
hypertension (dogs)
ROlHL-21498-02 Pathophysiology of edema (rats, cats)
ROlHL-22026-01 Endogenous prostaglandins in asthma
ROlHL-22233-01 Characterization of bio-materials by
elastic property
ROIHL-22506-01 Hemodynamics of the clinical
hypertensions
BOD
BODY FLUIDS, EXTRACEUULAR SPACE
(COMPARTMENT)
Ml Also CONNfCtlVI TI5SUf, GROUND MlhMANCf
ROIHI 02163 20 Kinetics ol wiler and elertrolytti In
shock (dogs, rnh)
" PUIMI II6/H 11 0015 Cardiovatcultr dynamici end Ihfir
Lonliol lymph How rale and protein concentration (dogl)
" POIHI 116/8 II 0039 Cardiovascular dynamics and their
control Capillary and inlerilitial lluid dynamics ol Ihe
intestine (cats)
POIHL 116/8 II 0040 Cardiovascular dynamics and their
control Control of plasma potassium concentration (dors)
" POIHI II6/K n 005/ Cardiovascular dynamics and Iheir
control Return of urine lo circulation using cystico caval
shunt (dogs)
POIHL 116/8 II 00/0 Cardiovascular dynamics and their
control Interaction ol Ihe lour Starling forces (dogs)
ROIHL 13841 16 Respiration during altitude
acclimatization (goals, dogs, rats, rabbits)
P50HL 14159 08 0008 Specialized center ol research in
hypertension Renal function and sodium metabolism in
hypertension (rats, human, rabbits)
P50HL 14214 07 0025 Newborn lung center for hyaline
membrane disease Pulmonary vascular permeability and
lung water Hyaline membrane disease (sheep)
POIHL 14388 0/ 0154 Regulation of the circulation in
pathological states Energetics of smooth muscle
contraction (rats)
POIHL 15835-06 0023 Study of muscles related to heart
disease Cellular basis ol the Frank Starling curve (Irogs,
rats)
ROIHL 16658 05 Intrarenal regulation of sodium
reabsorption
ROIHL 17366-05 Mechanisms in the production of renal
hypertension (rabbits, dogs)
P50HL 18318-03 0004 Pathogenesis and complications of
hypertension Steroid and renin profiles in hypertension
(rats, human)
P50HL-18318-03 0007 Pathogenesis and complications of
hypertension Humoral factors and renal function in
experimental hypertension (rats)
P50HL-18318-03 0010 Pathogenesis and complications of
hypertension - Hemodynamics in mineralocorticoid and low
renin hypertension (human)
POlHL-18575-03 0002 Mechanisms of vascular changes
in hypertension - Endocrines. electrolytes, and
hemodynamics in hypertension (pigs)
ROlHL-20153-02 Intracellular pH and myocardial
electropharmacology (dogs, guinea pigs)
ROlHL-2074901
(sheep)
ROlHL-20878 02
Developing heart -Biophysical aspects
Cellular aspects of lung injury (rats.
Dynamics of interstitial space in whole
*£icludes routine methodokigy OR covers only general projects wtilch preclude indexing
"Oriented significantly to above subject
at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
rabbits)
** R01HL-2I282-01
animals (rats)
** ROlHL-22261-01 Compliance of fluid spaces in advancing
hypertension (rats)
ROlHL-22281-01 Microprobe analysis and metabolite
levels of ischemic mycardium (dogs)
ROlHL-22594-01 Reflex control of the circulation in heart
failure (dogs)
POIHL 22619-01 0008 Cellular mechanisms of heart
failure - Molecular mechanisms and differential contractile
responsiveness in VSM (dogs)
ROlHL-22911-01 Mechanism of clearance of lung edema
fluid (dogs)
ROlHL-23201-01 Mechanisms of hypertension (human,
rats)
BODY FLUIDS, EXUDATES AND TRANSUDATES
SEE ALSO BODY FLUID BALANCE, EDEMA
POlHL-10342-13 0006 The integrated function of
respiration and circulation - Lung inflation effects on
pulmonary vasculature and interstitial space (dogs)
ROlHL-13596-07 Clearance of plasma proteins from
alveoli
POlHL-15832-06 0010 Chemical-structural predispositions
to lung injury - Kinin generating systems in pulmonary
disease (human, animals)
BODY FLUIDS, MILK
SEE ALSO REPRODUCTIVE SYSTEM FEMALE, MAMMARY
GLANDS
ROlHL-18712-03 Iron deficiency-hyperlipidemia in
development (rats)
BODY FLUIDS, MUCUS
SEE ALSO PROTEOGLYCANS, MUCIN
SEE ALSO RESPIRATORY SYSTEM, BRONCHIAL MUCUS
ROlHL-14271-07 Physico-chemical properties of tracheal
mucus (dogs, frogs)
ROIHL-16730-03 Physiology of mucociliary transport (rats,
frogs, rabbits)
** P50HL-19157-02 0003 Studies in cystic fibrosis and
bronchiolitis - Nasal mucosal function in patients with
cystic fibrosis
** P50HL-19157-02 0004 Studies in cystic fibrosis and
bronchiolitis - Macromolecular regulators of mucus
secretion-Invertebrate model
BODY FLUIDS, SPUTUM
SEE ALSO ORAL-PHARYNGEAL. SALIVA
SEE ALSO RESPIRATORY SYSTEM. BRONCHIAL MUCUS
(contd)
BOD
R01HLU844-06 Mucous glycoprotein in human tespiratorv
epithelium (also wheat)
P50HL-19160-02 0002 Mucus abnormality in cystic
fibrosis - Ultrastructure, cytochemistry of pulmonary
secretion (human, rat)
BODY FLUIDS, TISSUE SPACES
POlHL-06285-18 0212 Cardiovascular-respiratory
physiology and biochemistry - Membrane structure and
function-Gap junction (bovine)
BODY FLUIDS, VISCOSITY-VISCOELASTICITY
SEE ALSO BLOOD VISCOSITY-VISCOELASTICITY
** R01HL-U271-07 Physico-chemical properties of tracheal
mucus (dogs, frogs)
*• ROlHL-15155-05 Rheology of pulmonary secretions (dogs)
ROlHL-16730-03 Physiology of mucociliary transport (rats,
frogs, rabbits)
ROlHL-20989-01 Pathophysiology of bronchial asthma
(sheep, dogs)
BODY FLUID BALANCE, ACID-BASE
SEE ALSO ACIDS-BASES, HYDROGEN-ION CONCENTRATION
SEE ALSO RESPIRATORY GAS LEVELS, BOHR EFFECT
SEE ALSO URINE ACIDITY
♦* R01HL-00340 29 Electrolyte disturbance in cardio-renal
disease (human, dogs, rats)
** R01HL-00759-29 Regulation of electrolyte and acid base
equilibrium (dogs)
ROlHL-02363-20 Kinetics of water and electrolytes in
shock (dogs, rats)
POlHL-06285-18 0182 Cardiovascular-respiratory
physiology and biochemistry - Structure and function of
vascular chemoreceptors (cats, rats)
POlHL-06285-18 0188 Cardiovascular-respiratory
physiology and biochemistry - Physiology and pharmacology
in regulation of airways-hyperirritability (animals)
** POlHL-06285-18 0197 Cardiovascular-respiratory
physiology and biochemistry - Microperfusion and
micropuncture of renal tubules (hamsters, desert rats)
POlHL-06285-18 0198 Cardiovascular-respiratory
physiology and biochemistry - Renal tubular secretion of
hydrogen ion (animals)
P01HL-08805-15 0006 Regulation of ventilation and
pulmonary circulation - Adaptation of lungfish-Estivation
P01HL-08899-14 0031 Tolerance to respiratory gases in
health and disease - Studies in exercise (human, dogs)
** P01HL-08899-14 0033 Tolerance to respiratory gases in
health and disease - Acid-base related influences of
hypoxia (human)
•* P01HL-08899-U 0034 Tolerance to respiratory gases in
health and disease - Hyperoxygenation and respiratory
response to acid-base stimuli (human, dog)
POlHL-08899-14 0041 Tolerance to respiratory gases in
health and disease - Blood gas transport and brain
circulatory control (human)
** POlHL-10342-13 0023 The integrated function of
respiration and circulation - Carbon dioxide transport and
CSF acid base balance (hogs, pigs)
ROlHL-12677-10 Surgical physiologic studies of isolated
kidneys (dogs, rats)
R01HL-12777-09 Mechanisms in cardiac performance
(dogs, human)
ROlHL-13257-09 Inhalation anesthesia on myocardial
metabolism (dogs, swine, human)
P50HL-14218-07 0004 Pulmonary SCOR-Newborn lung
center - Metabolism of infants with respiratory distress
syndrome (human)
*• P50HL-14218-07 0018 Pulmonary SCOR-Newborn lung
center - Whole body buttering in acute hypercapnia (dogs)
POlHL-144 14-07 0010 Environmental influences on
cardiorespiratory and cellular functions - Pressure effects
on cardiac electrical phenomena (animals)
** POlHL-14414-07 0014 Environmental influences on
cardiorespiratory and cellular functions - Temperature and
acid-base status In tissues, cells, and subcellular system
ROlHL-14720-08 Factors governing the renal excretion of
acid (humans, rats)
** P60HL-15157-07 0012 Comprehensive center for sickle
cell disease - Sickling and intracellular pH (human)
ROIHL 15469-06 Human ventilatory adaptation (also,
dogs, rats)
*• ROIHL- 158 10-06 Electrolyte physiology and respiratory
acid-base (dogs)
ROlHL-16292-05 0002 Surgeiy and non-obstructive
coronary insufficiency - Effects of hypothermia during
cardiopulmonary bypass (dogs)
ROlHL-16463-05 Localization of airways obstruction and
responses
ROIHL 16916-04 0002 The role of albumins in lung water
accumulation ■ Lung water balance-Forces, models and
albumin concentrations (rabbits, dogs)
ROlHL-17352-03 Physiological regulation during chronic
hyperthermia (sheep)
ROlHL-17629-03 Developmental aspects of cardiovascular
function (human, cats, rabbits)
POIHL-17731-04 0010 Physiological basis of pulmonary
disease - Gas exchange kinetics (dogs)
ROIHL- 17963-04 Human erythrocyte carbonic anhydrase
ROlHL-18082-03 Erythrocyte phosphates and vertebrate
gas transport (amphibians, reptiles)
•* ROlHl-18351-03 Brain metabolism, acid-base balance,
and respiration
70
ROlHL-18371-03 Pulmonary hypertension and ventilation
pathophysiology (dogs)
ROlHL-18489-03 Hemodynamic interactions of vasoactive
chemicals (rats)
ROlHL-18798-04 0001 Nervous and ionic factors in
sudden cardiac death - Potassium loss during myocardial
ischemia (rabbits)
P50HL-191 90-02 0006 Pulmonary SCOR -Pathophysiology,
management of IRDS - Asphyxia-Respiratory control (dogs)
P50HL-191 90-02 0007 Pulmonary SCOR -Pathophysiology,
management of IRDS - Asphyxia-Cerebral metabolism (dog,
rat)
POlHL-19737-02 0005 Cellular and molecular aspects ot
respiratory physiology - Interaction of respiratory exchanges
and blood gas parameters (human, animals)
** ROlHL-201 53-02 Intracellular pH and myocardial
electropharmacology (dogs, guinea pigs)
ROlHL-20262-02 Cardiac glycosides and the mechanism
of the sodium-potassium pump
ROlHL-20568-03 Respiration during prolonged hypercapnia
(rats)
ROlHL-20635-03 Factors in lung development (rat and
chick embryo)
ROlHL-22258-01 New aspects of pharmacology related to
carbonic anhydrase
R23HL-22575-01 Factors modifying cardiac digoxin effects
and content (dogs, cats)
** ROlHL-22650-01 Regulatory mechanisms of erythropoietin
production (human, rats, mice)
BODY FLUID BALANCE, ACID-BASE, ACIDOSIS
SEE ALSO CARBOHYDRATES METABOLISM DISORDERS.
DIABHIC ACIDOSIS
SEE ALSO KETONE BODIES
SEE ALSO METABOLIC DISORDERS (INBORN), RENAL
TUBULAR ACIDOSIS
SEE ALSO RESPIRATORY DISORDERS. ACIDOSIS,
RESPIRATORY
ROlHL-02888-22 Interrelationships of circulation and
respiration (opossum, cats)
POlHL-06285-18 0125 Cardiovascular-respiratory
physiology and biochemistry - Myocardial function in the
fetal and neonatal lamb
POlHL-06285-18 0188 Cardiovascular-respiratory
physiology and biochemistry - Physiology and pharmacology
in regulation of airways-hyperirritability (animals)
POlHL-06296-18 0005 Cardiovascular and pulmonary
adaptation to stress ■ Regulation of ventricular
performance (animals)
** ROlHL-08659-14 Myocardial performance and metabolism
In the newborn (sheep)
POlHL-08899-14 0035 Tolerance to respiratory gases in
health and disease - Simulation of the increased
metabolism of exercise (dogs)
POlHL-10436-13 0005 A multidisciplinary study of
congenital heart disease - Pulmonary physiology In
congenital heart disease (human)
ROlHL-11046-12 Renin, angiotensin, steroids, ions and
blood pressure (human, sheep, rabbits)
POlHL-11351-12 0015 Cellular and molecular
mechanisms of myocardial function - Effects of hypoxia
and ischemia on ion exchange and heart function (rabbits)
ROlHL-1 1907-08 Mechanisms of physiological responses
to exercise (human, dogs)
POlHL-14414-07 0014 Environmental influences on
cardiorespiratory and cellular functions - Temperature and
acid-base status in tissues, cells, and subcellular system
ROlHL-14646-05 Pathophysiology of myocardial ischemia
(dogs, rats)
POlHL-14985-07 0003 Adaptation to hypoxia - Hypoxia
and oxygen transport (human, dogs)
•* POlHL-14985-07 0005 Adaptation to hypoxia - Control
mechanisms in the pulmonary microcirculation (animals)
ROlHL-15522-06 Influence of mannitol on ischemia
cardiac muscle (dogs, cats, rats)
POlHL-15832-06 0007 Chemical-structural predispositions
to lung injury - Inactivation of vasoactive agents by the
lung (human, rats, cats, dogs)
ROlHL-16022-05 Determinants of the ventilatory response
to hypoxia (goats, cats)
** P50HL-17669-04 0006 Ischemic heart disease center
(SCOR) Studies of hypoxic, acidotic and ischemic cardiac
muscle (dogs)
P50HL-17669-04 0007 Ischemic heart disease center
(SCOR) - Relationship between myocardial depression and
compliance (dogs, cats)
P50HL-17569-04 0011 Ischemic heart disease center
(SCOR) - Lysosomal function and lysosomal enzymes in
normal and ischemic heart (rabbit)
P50HL-17669-04 0022 Ischemic heart disease center
(SCOR) - Pathological studies of human and experimental
ischemic heart disease
P50HL-17682-04 0024 Study of ischemic heart disease ■
Phosphorylation of cardiac contractile proteins during
ischemia (rat, guinea pig)
ROIHL 18647-03 Ischemic myocardial injury in cultured
heart cells (rats)
ROlHL-194 10-03 Dynamic interrelations underlying
exercise hyperpnea (human)
** R23HL-19601-01 Cardiac response to chronic metabolic
acidosis (rats)
ROlHL-201 53-02 Intracellular pH and myocardial
electropharmacology (dogs, guinea pigs)
BOD
ROlHL-21187-01 Potassium, norepinephrine, and coronary
arterial tone (dogs)
R23HL-21262-02 Sodium-calcium interactions in
mammalian myocardium (rabbits, cats)
R23HL-22575-01 Factors modifying cardiac digoxin effects
and content (dogs, cats)
ROlHL-22650-01 Regulatory mechanisms of erythropoietin
production (human, rats, mice)
ROlHL-23128-01 Cardiac contractility-Ischemia and
hypoxia (rabbits, rats)
ROlHL-23166-01 Pathology of mitochondria in ischemic
myocardium (rats, cattle)
BODY FLUID BALANCE, ACID-BASE, ALKALOSIS
POlHL-08899-14 0030 Tolerance to respiratory gases in
health and disease - Dynamic characteristics of respiratory
control components (human, cats)
P50HL-14218-07 0018 Pulmonary SCOR-Newborn lung
center - Whole body buffering in acute hypercapnia (dogs)
ROlHL-14693-07 Survival value of physiological responses
to hypoxia (dogs)
POlHL-14985-07 0002 Adaptation to hypoxia - Oxygen
transport in man at high altitude
POlHL-14985-07 0003 Adaptation to hypoxia - Hypoxia
and oxygen transport (human, dogs)
POlHL-14985-07 0009 Adaptation to hypoxia - Influence
of chemosensitivity on control of breathing during sleep
(human, dogs)
** ROlHL-15810-06 Electrolyte physiology and respiratory
acid-base (dogs)
POlHL-15832-06 0007 Chemical-structural predispositions
to lung injury - Inactivation of vasoactive agents by the
lung (human, rats, cats, dogs)
ROlHL-16022-05 Determinants of the ventilatory response
to hypoxia (goats, cats)
ROlHL-16658-05 Intrarenal regulation of sodium
reabsorption
ROlHL-18328-03 Hemoglobin function and tissue
oxygenation (human, dogs)
ROlHL-18730-03 Role of mineralocorticoids in low renin
hypertension (human, rats)
R23HL-19601-01 Cardiac response to chronic metabolic
acidosis (rats)
ROlHL-20153-02 Intracellular pH and myocardial
electropharmacology (dogs, guinea pigs)
ROlHL-20196-02 Regulation of coronary arterial smooth
muscle
ROlHL-22390-01 Effect of chloride on renin (rats, dogs)
R23HL-22575-01 Factors modifying cardiac digoxin effects
and content (dogs, cats)
BODY FLUID BALANCE, ACID-BASE,
ANTIACIDOSIS DRUGS
P50HL-19 185-02 0007 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Sodium bicarbonate and
albumin in resuscitation of preterm infants (human)
BODY FLUID BALANCE, BODY WATER
SEE ALSO BIOLOGICAL TRANSPORT, FLUID EXCHANGE AND
TRANSPORT
SEE ALSO CELL FLUIDS, CELL WATER
SEE ALSO NUTRIENT INTAKE ACTIVITY. DRINKING BEHAVIOR
(WATER)
SEE ALSO NUTRIENT INTAKE ACTIVITY, THIRST
R01HL-00340-29 Electrolyte disturbance in cardio-renal
disease (human, dogs, rats)
ROlHL-02363-20 Kinetics of water and electrolytes in
shock (dogs, rats)
** POlHL-06312-17 0047 Surgical cardiology - Myocardial
extravascular water (dogs)
** POlHL-1 1578-11 0027 Cardiovascular dynamics and their
control - Vasopressin and thirst in control of body fluid
volumes and osmolality (dogs)
POlHL-11678-11 0035 Cardiovascular dynamics and their
control - Lymph flow rate and protein concentration (dogs)
** POlHL-11678-11 0046 Cardiovascular dynamics and their
control - Regulation of aldosterone secretion and related
factors (dogs)
POlHL-11678-11 0058 Cardiovascular dynamics and their
control - Overall control of the circulation-Computer
analysis
ROlHL-12690-09 Systemic and local vascular adjustment
in shock (monkeys, cats)
P50HL-14159-08 0008 Specialized center of research in
hypertension - Renal function and sodium metabolism in
hypertension (rats, human, rabbits)
P50HL-14214-07 0025 Newborn lung center for hyaline
membrane disease - Pulmonary vascular permeability and
lung water-Hyaline membrane disease (sheep)
P50HL-14218-07 0017 Pulmonary SCOR-Newborn lung
center - Transvascular fluid exchange, vasoactive mediators
in RDS (sheep, cat)
P50HL-14218-07 0018 Pulmonary SCOR-Newborn lung
center - Whole body buffering in acute hypercapnia (dogs)
POlHL-14388-07 0192 Regulation of the circulation in
pathological states - Renal tubular secretion of magnesium
(rats)
POIHL 14414-07 0004 Environmental influences on
cardiorespiratory and cellular functions - Role of diffusion
in gas exchange (chicken egg)
ROlHL-15655-05 Blood flow and gas exchange in placenta
and lungs (sheep) rabbits)
(contd)
*Exdudes routine methodotogy OR covers only general projects which preclude
"Ohented significantly to above subject.
Indexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for Investigator's name and grant number
too
ROIHL 16916 04 000? Tht roll ol llbumlni In lung wit*r
<ccumul<lion lung watti hilince Fotc«, modals and
albumin concantrations (labbits. do|})
ROIHl 16916 04 0011 Tb« role of albumins in lung nalur
accumulation Wbola body disltibution and airhanie ol
albumin (rabbits, human, monkeyj)
ROIHI i;b;i 03 Study ot membrant parmeability by NMR
ralaiation (human)
POIHl 18575 03 0002 Machanisms ol vasculii changes
in hyp«rtansion Endocrints. tieclrolytes. and
hemodynamics m hypertension (pigs)
POINL \«bli 03 000b Mechanisms ot vascular changes
in hypertension Renin synthesis in normotensive and
hypertensive pigs (also rats, dogs)
PSOHL 191SS 02 0001 Pathophysiology ot pulmonary
edema Pulmonary edema study unit (human, dog)
ROIHL 20861 01 Cardio-raspiritoiy renal stress reactions
(dogs)
ROIHL 2180001
excretion
ROIHL 2261701
(sheep)
ROIHL 2285901
Angiotensin effects on water intake and
Angiotensin, hypertension and the CNS
Effect of carbon mononide on the
developing heart (rats)
BODY FLUID BALANCE, BODY WATER,
DEHYDRATION
SEE ALSO BODY FLUID BALANCE. BODY WATER LOSS
POIHL 11678 11 0040 Cardiovascular dynamics and their
control Control ot plasma potassium concentration (dogs)
P60HL 15157 07 0018 Comprehensive center lor sickle
cell disease Red blood cell membrane physiology in sickle
cell anemia (human)
ROIHL 1920903 Role of ADH in experimental renal
hypertension (dogs, rats)
ROIHL 2205101 Role of angiotensin II in vasopressin
release (human)
BODY FLUID BALANCE, BODY WATER EXCESS
SEE ALSO BODY FLUID BALANCE. EDEMA
ROlHL-20110'02 Microwave methods of lung water
measurement (dogs, phantom models)
BODY FLUID BALANCE, BODY WATER LOSS
SEE ALSO BODY FLUID BAUNCE. BODY WATER.
DEHYDRATION
SEE ALSO SKIN SECRETIONS. SWEAT
SEE ALSO URINE*
ROlHL-1935203 Respiratory heat and water loss in
neonates
ROlHL-21126-02 Exercise-induced bronchospasm in
children
BODY FLUID BALANCE, EDEMA
SEE ALSO BODY FLUIDS, EXUDATES AND TRANSUDATES
SEE ALSO BRAIN DISORDERS. BRAIN EDEMA
SEE ALSO CAROIOVASCUUR DISORDERS, HYPERTENSION
(SYSTEMIC)
SEE ALSO CARDIOVASCULAR DISORDERS, HYPERTENSION
(SYSTEMIC). ANGIOTENSIN-RENIN-ALDOSTERONE-
ASSOCIATED
SEE ALSO EYE DISORDERS. PAPILLEDEMA
SEE ALSO METABOLIC DISORDERS INBORN, ANGIONEUROTIC
EDEMA (HEREDITARY)
SEE ALSO RESPIRATORY DISORDERS, PULfi/IONARY EDEMA
ROlHL-02493-22 Kidney function in experimental heart
failure (dogs, rats)
POlHL-06285-18 0143 Cardiovascular-respiratory
physiology and biochemistry - Myocardial ischemia (human,
dogs, lambs)
** POlHL-06664-17 0010 Cardiopulmonary function in
remediable vascular disease - Ischemia and acute renal
failure (rats)
** POlHL-1 1310-12 0053 Mechanisms of cardiovascular
disease Ventricular pressure-volume after cardipulmonary
bypass (dogs)
POlHL-11310-12 0063 Mechanisms of cardiovascular
disease - Myocardial function, metabolism and cellular
integrity after heart surgery (dogs)
P01HL-1I678-11 0035 Cardiovascular dynamics and their
control - Lymph flow rate and protein concentration (dogs)
POlHL-1 1678-11 0068 Cardiovascular dynamics and their
control - Basic hemodynamics (rats, dogs)
** ROlHL-12421-10 Pathophysiology of circulatory shock
(dogs, baboons)
R01HL12493-10 Bioengineering analysis of microvascular
function (cats, rabbits)
ROlHL-12974-10 Tracer kinetics, flows and masses in
body organs (human, dogs)
** ROlHL-13323-08 Intrarenal pressure and renal function
(human, dogs)
** POlHL-14388-07 0232 Regulation of the circulation in
pathological states - Idiopathic cyclic edema
ROlHL-15522-06 Influence of mannitol on ischemia
cardiac muscle (dogs, cats, rats)
R01HL-16658-05 Intrarenal regulation of sodium
reabsorption
** ROIHL- 17458-04 Renal control of sodium excretion (rats)
P50HL- 17665-04 0021 Study of ischemic heart disease -
Identification, prevention-Myocardial ischemia in
cardiopulmonary bypass (dog)
71
PbOHt 17667 04 002? Study ol ischemic heart diiaau
Preventing myocardial injury in surgery using
cardiopulmonary bypass (human, rat)
PbOHl 17669 04 0006 Ischamic heart dliaau center
(SCOR) Studies ol hypoxic, acidotic and iichimic cardiac
muscle (dogs)
P50HL 1/669 04 0022 Ischemic heart disease center
(SCOR) Pathological studies ol human and experimental
ischemic heart disease
ROIHL 18024 03 Regional myocardial flow and function
relationships (dogs)
POIHL 18646 03 0008 Studies basic to heart
transplantation Immunophysiology and early detection ol
reiection (dogs)
POIHL 1864603 0009 Studies basic to heart
transplantation Pathologic aspects ol cardiac allograft
reiection (sheep, dogs)
ROIHL 18862 02 Thirst and its contribution to edema
(dogs)
ROIHL 1967801 Quantification of intrathoracic fluid by
impedance (human, dogs)
ROIHL 20080 02 Surgically induced myocardial edema
(dogs)
ROIHL 20143 02 Hypothermic circulatory arrest Cerebral
vascular change (dogs)
ROIHL 20201 01 Hypertension and vascular steroid
receptors (rats)
ROIHL 20283 02 Maintenance of cellular integrity in
ischemic hearts (cats)
ROIHL 20648 01 Physical factors and coronary flow (dogs)
R23HL 21066 02 Angiotensin and prostaglandin control of
aldosterone (rats)
Pathophysiology of edema (rats, cats)
Natural history of the postphlebitic
Role of angiotensin II in vasopressin
•* R01HL21498-02
ROlHL-21572-01
syndrome
ROIHL 22051 01
release (human)
•* POlHL-22602-01 0002 Pathophysiology of the
endothelium Molecular charge and endothelial
permeability (rats, mice)
ROlHL-2360201 Physiology of renin, aldosterone and
prostaglandin (human, rats, dogs)
BODY FLUID BALANCE, IONIC
SEE ALSO ADRENAL GLANDS DISORDERS,
HYPERALDOSTERONISM
SEE ALSO BIOLOGICAL TRANSPORT, ACTIVE TRANSPORT, ION
PUMPS
SEE ALSO BIOLOGICAL TRANSPORT, ION EXCHANGE AND
TRANSPORT
SEE ALSO BLOOD TREATMENT. HEMODIALYSIS
SEE ALSO BODY FLUID BALANCE. ACID-BASE
SEE ALSO CALCIUM (MINERAL) BALANCE (METABOLISM)
SEE ALSO CAROIOVASCUUR DISORDERS. HYPERTENSION
(SYSTEMIC). ANGIOTENSIN-RENIN-ALDOSTERONE-
ASSOCIATED
SEE ALSO KIDNEY FUNCTION
SEE ALSO NUTRIENT INTAKE ACTIVITY, SALT INTAKE
ROlHL-02228-24 Respiration, circulation, and heat
regulation in exercise (bird, mammals)
ROlHL-02334-23 Micropuncture study of kidney function
(rats, animals)
** R01HL02363-20 Kinetics of water and electrolytes in
shock (dogs, rats)
** ROlHL-02493-22 Kidney function in experimental heart
failure (dogs, rats)
** ROlHL-03303-21 Factors regulating electrolyte excretion by
the kidney (human, dogs)
POlHL-06285-18 0145 Cardiovascular-respiratory
physiology and biochemistry • Pulmonary, pleural and
systemic microcirculation (animals)
" P01HL06285-18 0197 Cardiovascular-respiratory
physiology and biochemistry - Microperfusion and
micropuncture of renal tubules (hamsters, desert rats)
POlHL-06285-18 0200 Cardiovascular-respiratory
physiology and biochemistry - Medullary counter-current
system (animals)
" POlHL-063 12-17 0051 Surgical cardiology - Diuretic
therapy on myocardial electrolyte composition and water
content (human)
POlHL-06664-17 0037 Cardiopulmonary function in
remediable vascular disease - Salt and water balance of
cells and tissues (rabbits)
POlHL-06835-17 0048 Cardiovascular disease •
Aldosterone producing adenoma prediction of curability
(human)
** POlHL-0868215 0026 Regulation of the cardiovascular
system • Hypertension-High renin vs low renin (dog)
** POlHL-08682-15 0027 Regulation of the cardiovascular
system - Cardiac mechanoreceptors -Reflex regulation of
renal function (dogs)
** ROlHL-09906-13 0019 Membrane transport processes in
red blood cells - Hemoglobin change and membrane
potentials in red blood cells at varying volumes
ROlHL-106 12-13 0018 Humoral factors in heart failure
and hypertension - The pathogenesis of experimental renal
hypertension (dogs, rabbits, rats)
ROlHL-109 14-10 Renal sodium transport in experimental
aldosteronism (dogs)
** ROlHL-1 1046-12 Renin, angiotensin, steroids, ions and
blood pressure (human, sheep, rabbits)
M P01HL11678-11 Cardiovascular dynamics and their
control
BOD
POIHl 116/8 II 00?/ Cardiovaiculai dynamict and intii
control Vatoprtiiin and Ihirtt in control ol body lluid
volumtt and otmolality (do|t|
POIHl 116/8 II 0031 Cardiovaiculai dynamic! and than
control Hyparlantion caused by ilimulalion ol lanal
sympathetic nerval Idogi)
POIHl 116/8 II 0040 Cardiovascular dynamics and Ihair
control Control of plasma potaiiium concentration Idogi)
POIHl 116/8 II 0060 Cardiovascular dynamics and thair
control Salt and water balance in one kidney Goldblalt
hypertension (rat)
POIHl 1215/ II 0058 Functions and mechaniimi ol call
membrane ion transport Ionic and osmotic regulation in
loadfish A euryhaline aglomerular teleosl
ROIHL 1282/08 Regulation of sodium excretion (dogs,
rats)
ROIHl 1323/ 09 Erythrocytes during early development
(human, animals)
ROIHl 1342/ 09 Neural control of blood volume (monkeys.
dogs)
ROIHL 14306 07 Quantification of arterial pressure control
(dogs)
Regulation of the circulation In
Renal tubular secretion of magnesium
Regulation of the circulation in
Kallikrein kinin system in hypertension
Regulation of the circulation in
Kallikrein kinin system in hypertension
POIHL 1438807 0192
pathological states
(rats)
POIHL 1438807 0223
pathological states
(rats)
POIHL 1438807 0224
pathological states
(human)
ROIHL 14720 08 Factors governing the renal excretion of
acid (humans, rats)
ROIHL 1546906 Human ventilatory adaptation (also,
dogs, rats)
ROIHL' 158 10-06 Electrolyte physiology and respiratory
acid-base (dogs)
ROIHL 16657 06 Innervation of coronary arteries and heart
(rats)
PO1HL-16910-05 0001 Regulation of the peripheral
circulation - Quantitative studies of microcirculatory control
(bats)
ROlHL-17407-05 Peripheral circulation and fluid balance
(fish, mammals, human)
Cardiovascular and renal functions of
Studies in lung preservation (dogs)
Capillary transport of large molecules
ROlHL-17847-04
marmots
ROlHL-17944-03
ROlHL-1801004
(dogs, sheep)
ROIHL 18288-04 Intraoperative protection of the
myocardium (dogs, rats)
P50HL-18318-03 0007 Pathogenesis and complications of
hypertension - Humoral factors and renal function in
experimental hypertension (rats)
P50HL-18323 04 0011 SCOR hypertension center -
Endocrine profiling on a selected normal population
(human)
P50HL-18323-04 0037 SCOR hypertension center -
Adrenocortical factors in childhood hypertension
P50HL-18323-04 0045 SCOR hypertension center ■
Laboratory programs -Prorenin (human)
ROlHL-18426-04 Regulation of renal hemodynamics (dogs)
POlHL-18575-03 0002 Mechanisms of vascular changes
in hypertension - Endocrines. electrolytes, and
hemodynamics in hypertension (pigs)
ROlHL-18579-03 Vasoactive hormones and blood pressure
regulation (dogs, rats, rabbits)
ROlHL-18798-04 Nervous and ionic factors In sudden
cardiac death
Nervous and ionic factors in
Potassium loss during myocardial
ROlHL-18798-04 0001
sudden cardiac death
ischemia (rabbits)
ROlHL-18798-04 0002
sudden cardiac death
•Excludes routine methodokigy OR covers only general projects which preclude Indexing
**0nented significanthi to above subject.
at the specific level.
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
Nervous and ionic factors in
Electron microprobe, ultrastructure
analysis of ischemic myocardium (dog, rabbit)
R01HL18845-04 Regulation of renal circulation and salt
excretion (rats, dogs)
ROlHL-1886202 Thirst and its contribution to edema
(dogs)
ROlHL-19320-03 Angiotensin neuropharmacology -
Relationship to sodium
R23HL-19601-01 Cardiac response to chronic metabolic
acidosis (rats)
ROlHL-20176-02 Biochemistry and genetics of salt
hypertension (rats)
ROlHL-20190-02
(dogs)
ROlHL-20201-01
receptors (rats)
ROlHL-2086101
(dogs)
R23HL-21066-02
aldosterone (rats)
ROlHL-21092-02 Factors other than renin in renal
hypertension (rats)
ROlHL-21094-01 Arterial baroreceptors and renal function
(dogs)
ROlHL-21272-02 Sodium homeostasis and renal
prostaglandins (dogs)
R01HL-21274-0I Prorenin-Physiological and biochemical
analysis (human)
(contd)
Pathogenesis of cardiac hypertrophy
Hypertension and vascular steroid
Cardiorespiratory-renal stress reactions
Angiotensin and prostaglandin control of
BOD
** ROlHL-21525-02 Effect of cations, anions and water upon
blood vessels (dogs, rats)
ROlHL-21673-01 Pathophysiology of venous changes in
hypertension (rats, rabbits, human, dogs)
ROlHL-21800-01 Angiotensin effects on water intake and
excretion
ROlHL-22069-02 Experimental renal arterial hypertension
(dogs)
R23HL-22245-02 Functional characteristics of atrial
receptors (rats)
ROlHL-22411-01 Neuroendocrine involvement in
hypertension (rats)
ROlHL-22482-01 Circulatory hemodynamics and sodium
excretion (dogs)
R23HL-22575-01 Factors modifying cardiac digoxin effects
and content (dogs, cats)
ROlHL-23166-01 Pathology of mitochondria in ischemic
myocardium (rats, cattle)
** ROlHL-23600-01 Ions, water, and hypertension (human,
dogs, rats)
ROlHL-2360301 Morphogenesis of hypertensive vascular
disease (rats)
BODY FLUID BALANCE, IONIC, HYPERKALEMIA
P01HL10342-13 0024 The integrated function of
respiration and circulation - Cytochrome P450 and
physiological response to hypoxia (rats)
R01HL18796-04 Experimental cardiac arrhythmias (dogs)
ROlHL-1903003 Tissue protection during circulatory
interruption (dogs)
** ROlHL-21786-01 Long-term effects of myocardial
protection (dogs, rats)
ROlHL-22123-02 The role of the red cell in diabetic
atherosclerosis (human)
BODY FLUID BALANCE, IONIC, HYPOKALEMIA
SEE ALSO CARDIOVASCULAR DISORDERS, HYPERTENSION
(SYSTEMIC), ANGIOTENSIN-RENIN-ALDOSTERONE-
ASSOCIATED
SEE ALSO METABOLIC DISORDERS INBORN, BARTTER'S
SYNDROME
R01HL-00340-29 Electrolyte disturbance in cardio-rena!
disease (human, dogs, rats)
ROlHL-00759-29 Regulation of electrolyte and acid base
equilibrium (dogs)
" R01HL-02986-21 Zonal renal change with potassium
deficiency (rats, human)
ROlHL-03303-21 Factors regulating electrolyte excretion by
the kidney (human, dogs)
POlHL-06835-17 0059 Cardiovascular disease ■
Metyrapone-induced hypertension in dog
ROlHL-1 1046-12 Renm, angiotensin, steroids, ions and
blood pressure (human, sheep, rabbits)
•* R01HL-12792-09 Local control of the microcirculation
(hamsters, rats)
** ROlHL-12997-07 Myocardial defects induced by potassium
depletion (human, rats, cats)
ROlHL-16918-05 Role of steroids in hypertension (human)
ROlHL-1873003 Role of mineralocorticoids in low renin
hypertension (human, rats)
ROlHL-19933-02 Membrane and red cell dysfunction in
hemolytic anemia (human)
** ROlHL-21525-02 Effect of cations, anions and water upon
blood vessels (dogs, rats)
RClHL-22390-01 Effect of chloride on renin (rats, dogs)
ROlHL-23602-01 Physiology of renin, aldosterone and
prostaglandin (human, rats, dogs)
BODY FLUID BALANCE, IONIC, HYPONATREMIA
RGlHL-00759-29 Regulation of electrolyte and acid base
equilibrium (dogs)
POlHL-06835-17 0047 Cardiovascular disease -
Spironolactone in primary aldosteroidism (human)
P01HL06835-17 0049 Cardiovascular disease - Selective
hypoaldosteronism (human)
POlHL-06835-17 0050 Cardiovascular disease ■ 18-
Hydroxylase block in the 17 alpha-hydroxylase deficiency
syndrome (human)
ROlHL-10612-13 0018 Humoral factors in heart failure
and hypertension - The pathogenesis of experimental renal
hypertension (dogs, rabbits, rats)
POIHL 11678-11 0001 Cardiovascular dynamics and their
control - Body fluid volumes in the genesis of hypertension
(rats, dogs)
BODY FLUID BALANCE, IONIC, SALT GLAND
ROlHL-16318-21 Biochemistry and pharmacology of Na-K
transport
BODY FLUID BALANCE, OSMOTIC PRESSURE
SEE ALSO BLOOD OSMOTIC PRESSURE
SEE ALSO CELL FLUIDS, OSMOTIC PRESSURE
SEE ALSO SENSE ORGANS, OSMORECEPTORS
** POlHL-06285-18 0199 Cardiovascular-respiratory
physiology and biochemistry - Renal tubular reabsorption of
sodium chloride (hamsters, rabbits)
ROIHL 10881 13 Structure and function of
microcirculation (hamsters, rats, cats, dogs)
*• POlHL-11678-11 0027 Cardiovascular dynamics and their
control - Vasopressin and thirst in control of body fluid
volumes and osmolality (dogs)
POlHL-1 1678-11 0035 Cardiovascular dynamics and their
control - Lymph flow rate and protein concentration (dogs)
72
POlHL-1 1678-11 0036 Cardiovascular dynamics and their
control - Pulmonary capillary dynamics and edema (dogs)
POlHL-1 1678-11 0039 Cardiovascular dynamics and their
control - Capillary and interstitial fluid dynamics of the
intestine (cats)
** POlHL-11678-11 0057 Cardiovascular dynamics and their
control - Return of urine to circulation using cystico-caval
shunt (dogs)
POlHL-11678-11 0070 Cardiovascular dynamics and their
control - Interaction of the four Starling forces (dogs)
POlHL-121 57-11 0058 Functions and mechanisms of cell
membrane ion transport - Ionic and osmotic regulation in
toadfish -A euryhaline aglomerular teleost
ROlHL-12792-09 Local control of the microcirculation
(hamsters, rats)
M ROlHL-12879-09 Pulmonary transport and metabolism in
vivo
** ROlHL-12879-09 0002 Pulmonary transport and
metabolism in vivo - Osmotic compartmental model of
barrior exchange
P01HL-14388-07 0192 Regulation of the circulation in
pathological states - Renal tubular secretion of magnesium
(rats)
ROlHL-15655-05 Blood flow and gas exchange in placenta
and lungs (sheep) rabbits)
P50HL-17665-04 0021 Study of ischemic heart disease -
Identification, prevention-Myocardial ischemia in
cardiopulmonary bypass (dog)
ROlHL-18426-04 Regulation of renal hemodynamics (dogs)
ROlHL-20080-02 Surgically induced myocardial edema
(dogs)
ROlHL-21376-02 Blood-gas barrier solute and water
transport (rabbits)
R23HL-22933-01 Transvascular fluid and protein exchange
in the lung (sheep)
ROlHL-23015-01 Mechanisms of hypo-oncotic pulmonary
edema (human, dogs)
BODY FLUID BALANCE, OSMOTIC PRESSURE,
HYPEROSMOLARITY
P50HL-17669-04 0006 Ischemic heart disease center
(SCOR) - Studies of hypoxic, acidotic and ischemic cardiac
muscle (dogs)
P50HL-17669-04 0022 Ischemic heart disease center
(SCOR) - Pathological studies of human and experimental
ischemic heart disease
ROlHL-17944-03 Studies in lung preservation (dogs)
ROlHL-18590-03 Cerebral blood flow after cardiac arrest
(dogs, monkeys)
ROlHL-19030-03 Tissue protection during circulatory
interruption (dogs)
R23HL-21663-01 Regulation of collagen biosynthesis
(chick, embryo)
BODY FLUID BALANCE THERAPY
SEE ALSO BLOOD TREATMENT, HEMODIALYSIS
SEE ALSO NUTRITION, DIET THERAPEUTIC, SALT RESTRICTED
R01HL-02363-20 Kinetics of water and electrolytes in
shock (dogs, rats)
ROlHL-13172-10 Post-trauma lung mechanics and fluid
exchange (human, dogs, monkeys)
BODY MOVEMENT DISORDERS
SEE NEUROMOTOR DISORDERS
BODY MOVEMENT SENSE
SEE SENSORY-PERCEPTUAL PROCESSES, PROPRIOCEPTION
BODY PHYSICAL CHARACTERISTICS (GENERAL)
SEE ALSO SKELETAL DISORDERS DIAGNOSIS (INCL E)(AMS)*
** P50HL-14136-07 0004 Pulmonary SCOR-Airways
obstructive diseases - Morphometric studies of developing
emphysema (human)
P50HL-15103-07 0001 A/S SCOR-Early natural history of
arteriosclerosis - Clinical research-Bogalusa heart study
(children)
** ROlHL-18639-03 Human anatomy for cardiac prostheses
(human)
ROlHL-19859-03 Epidemiological studies, precursors of
hypertension (human)
ROlHL-19864-03 0001 Blood pressure of children and
young adults - Follow up of students from Dormont,
Pennsylvania
ROlHL-19869-03 Antecedents of adolescent hypertension
(human)
ROlHL-19870-03 Hypertensive progeny-Physical and
humoral precursor search
ROlHL-19956-03 High blood pressure in the young
(human)
ROlHL-19984-02 Blood pressure and immunogenetic
factors in the young (human)
ROlHL-20124-02 Coronary risk factors (human)
ROlHL-20159-03 Genetic epidemiology of precursors of
hypertension (human)
NO lHV-530 10-03 NAS-NRC twin registry
BODY POSITION SENSE
SEE SENSORY-PERCEPTUAL PROCESSES. PROPRIOCEPTION
BODY REGIONS (GENERAL)
SEE ALSO ORAL-PHARYNGEAL (REGION)
SEE ALSO SKELETAL SYSTEM. LIMB
P01HL-13480-09 0017 Cardiac electrophysiology - Body
surface potential mapping (human, dogs)
BOD
BODY REGIONS, ABDOMEN
POlHL-14414-07 0007 Environmental influences on
cardiorespiratory and cellular functions - Neural control of
respiration (human, cats)
POlHL-21584-02 0004 Respiratory mechanics In normal
and abnormal states - Effects of anesthesia on respiratory
mechanics (dogs)
BODY REGIONS, THORAX
SEE ALSO BODY CAVITIES, PLEURAL CAVITY
SEE ALSO INJURIES, CHEST
SEE ALSO RESPIRATORY FUNCTION, RESPIRATION, THORACIC
PRESSURE
** P01HL-14580-07 0003 Program project in respiratory
mechanics - Chest wall mechanics and respiratory control
(human, dogs)
ROlHL-16292-05 0020 Surgery and non-obstructive
coronary insufficiency - Limitation of transthoracic ECG in
detecting subendocardial ischemia (dogs)
** ROlHL-18639-03 Human anatomy for cardiac prostheses
(human)
P50HL-19170-02 0006 Harvard pulmonary SCOR-Chronic
diseases of the airways - Mechanism of overdistension
(human, animal)
R01HL-19678-01 Quantification of intrathoracic fluid by
impedance (human, dogs)
R01HL-20110-02 Microwave methods of lung water
measurement (dogs, phantom models)
R23HL-21406-01 Respiratory muscles in regulation of
infant breathing (human)
POlHL-2 1584-02 0004 Respiratory mechanics in normal
and abnormal states - Effects of anesthesia on respiratory
mechanics (dogs)
BODY TEMPERATURE
SEE TEMPERATURE (BODY)
BODY TEMPERATURE REGULATION
SEE TEMPERATURE (BODY) REGULATION
BODY VOLUME
ROlHL-13172-10 Post-trauma lung mechanics and fluid
exchange (human, dogs, monkeys)
BODY WATER BALANCE
SEE BODY FLUID BALANCE, BODY V<ATER
BODY WATER EXCESS
SEE BODY FLUID BALANCE, BODY WATER EXCESS
BODY WATER LOSS
SEE BODY FLUID BAUNCE, BODY WATER LOSS
BODY WEIGHT
SEE ALSO AGE (ANIMAL), INFANTS. BIRTH WEIGHT
SEE ALSO GROW/TH AND DEVELOPMENT
R01HL-01979-22 Arteriosclerosis in zoo animals on
controlled diets (animals)
ROlHL-03299-21 Dietary effects on cholesterol metabolism
(rats, rabbits)
POlHL-06835-17 0017 Cardiovascular disease - Studies
on obese hypertensive rats
POlHL-06835-17 0018 Cardiovascular disease - Fatty
acid concentration (rats)
POlHL-06835-17 0019 Cardiovascular disease - Fatty
acid distribution (rats)
POlHL-06835-17 0020 Cardiovascular disease ■ Lipid
metabolism (rats)
POlHL-06835-17 0024 Cardiovascular disease - Studies
on the obese spontaneously hypertensive rat
POlHL-06835-17 0046 Cardiovascular disease - Renin
activity during salt depletion in essential hypertension
(human)
R01HL-U901-12 0019 Effects of metabolic surgery on
the hyperlipidemias - Cholesterol, bileacids, lipoproteins in
obese humans
ROlHL-15174-06 CV disease epidemiology-Second
generation studies (human)
ROlHL-18040-04 Waveform dependency in defibrillation
(calves)
ROlHL-18235-03 Cardiovascular fitness and other risk
factors (human)
ROlHL-19858-03 UMMC-Blood pressure precursors and
consequences (human)
ROlHL-19864-03 0001 Blood pressure of children and
young adults - Follow up of students from Dormont,
Pennsylvania
ROlHL-20629-02 Catheter ventricular defibrillation studies
(dogs)
ROlHL-22123-02 The role of the red cell in diabetic
atherosclerosis (human)
BODY WEIGHT, OBESITY
SEE ALSO METABOLIC DISORDERS INBORN, OBESITY
HEREDITARY HYPERGLYCEMIC
SEE ALSO NUTRIENT INTAKE ACTIVITY, APPETITE
DEPRESSANTS
SEE ALSO NUTRITION, DIET THERAPEUTIC, REDUCING DIET
R01HL-02063-23 Biochemistry and function of lipids and
cell membranes (human, yeast, animals)
** POlHL-06835-17 0017 Cardiovascular disease - Studies
on obese hypertensive rats
POlHL-06835-17 0018 Cardiovascular disease - Fatty
acid concentration (rats)
(contd)
•Excludes routine methodotogy OR covers only general projects which preclude indexing at the specific level.
**Oriented significantly to above subject.
M Grant has subproiects describing specific research aspects.
See Appendix for investigator's name and grant number.
P0tHl0683!> i; 0019 Ctidlovticulir dlMlsr Lilly
icid distiibulion (latsl
POIHl 0683!) 17 0020 Ctidlovisculai disaast liiiid
matabolisni dais)
POIH1.0683!> U 00.'4 Catdiovaicuiai disaas* Studias
on tha obaja spontaneously liypertansiva lat
ROIHl 09914 13 The inyocaidium in diabetes mellitus
(dogs, inonkeys)
Eltects ol metabolic surgery on
Partial ileal bypass (human)
Etiects ol metabolic surgery on
Ellecl ot bypass on gasliin levels
ROIHI 11901 U 0001
the hyperlipidenuas
ROIHL 11901 12 OOM
the hyperlipidenuas
(dogs, human)
ROIHL 11901 12 0019
the hyperlipidemias
obese humans
ROIHI 11901 12 0020
the hyperlipidemias
EMects ot metabolic surgery on
Cholesterol, bileacids. lipoproteins in
Ellects ol metabolic surgery on
leiuno ileal bypass Endogenous
animal model ol obesity (rats)
ROIHL I208S 10 Lipoproteincarbohydtate ntetabolism
(human, lats)
ROIHL 1362606 Lipoprotein lipase and lipoprotein
removal (human, rats, bjcteria)
P50HL 14164 07 0041 A/S SCOR Comparative and
experimental atherosclerosis Nonhuman primate pediatric
atherosclerosis risk lactor
P50HL 1423007 0088 A/S SCOR Lipids, atherosclerosis
and thrombosis Coronary risk tactors in school children
The Muscatine study
P50HL 14236-05 0009 Prevention ol premature
arteriosclerosis - Clinical studies on cholesterol metabolism
(human)
POIHL- 1498507 0004 Adaptation to hypoxia Control ol
breathing in respiratory tailure (human, dogs)
P01HL1498507 0009 Adaptation to hypoxia Inlluence
ol chemosensitivity on control ol breathing during sleep
(human, dogs)
P50HL1510307 0001 A/S SCOR Early natural history ol
arteriosclerosis Clinical research Bogalusa heart study
(children)
R01HL1677404 Genetic epidemiology ol hyperlipemia
(Honolulu)
P50HL- 183 18-03 0002 Pathogenesis and complications ol
hypertension - Core experimental animal lacility (rats.
rabbits)
P50HL-19362-02 0002 A/S SCOR -Atherosclerosis in
nonhuman primates - Inlant caloric intake, adipose tissue
development and atherosclerosis (baboon)
R01HL1987003 Hypertensive progeny-Physical and
humoral precursor search
R01HL19877-02 Prevention ol high blood pressure in
children
ROlHL-20159-03 Genetic epidemiology ol precursors ol
hypertension (human)
ROlHL-20439-02 Ellects ol insulin on neurovascular
transmission (human, rats, rabbits, hamsters)
ROlHL-21010-02 Glycemia. other traits and CV death in
40.000 persons
ROlHL-21416-02 Atherosclerosis in nev» modles o!
diabetes mellitus
R23HL-22345-02 0001 Behavioral cardiovascular
compliance strategies - Long term modilication of dietary
patterns (human)
ROlHL-22378-01 Psyco-somatic predictors ol CHO in
adolescence (human)
** ROlHL-23201-01 Mechanisms of hypertension (human.
rats)
N01HV.12159-09 Lipid research clinic
NOlHV-6295504 Data collection in clinical pathology and
morbid anatomy (men)
BOHR EFFECT
SEE RESPIRATORY GAS LEVELS. BOHR EFFECT
BOMBAY BLOOD GROUP
SEE BLOOD GROUPS. BOMBAY
BOMBESIN
SEE ENDOCRINOLOGY. HORMONES. PEPTIDE-POLYPEPTIDE
HORMONES
BOND CLEAVAGE
SEE CHEMICAL BONDS. BOND CLEAVAGE
BOND FREQUENCIES
SEE CHEMICAL BONDS, VIBRATIONS
BONOS
SEE CHEMICAL BONDS
BONE
SEE SKELETAL SYSTEM. BONE
BONE CIRCULATION
SEE SKELETAL SYSTEM CIRCUUTION
BONE DENSITY
SEE SKELETAL SYSTEM. BONE DENSITY
BONE MARROW
SEE BLOOD AND RE SYSTEM. BONE MARROW
BONE MARROW DISORDERS
SEE BLOOD AND RE DISORDERS, BONE MARROW
73
BONE MARROW OIANT CELLS
SI I HIOIID AND Rl SYSIIM Ml liAMRYOCYIf S
BONE MARROW LYMPHOCYTES
sii moon cms, h iymcmocyiis
BONE MARROW TRANSPLANTATION
Slf BIOOO AND Rf SYSIIM, HON! MARROW
IRANSPLANIAIION
BONE NECROSIS
S!l SKIiriAl DISORDERS, BONE NECROSIS
BONE NECROSIS ISCHEMIC
SEt SKIIFIAl DISORDERS, BONE NECROSIS ISCHEMIC
BONE PROSTHESIS
SFE SKELETAL TISSUE PROSTHESIS. BONE
BONE SCANNING
SEE SKELETAL VISUALIZATION, BONE SCANNING*
BORANES
SEE METALS. BORON COMPOUNDS, BORANES
BOROHYDRIDES
SEE METALS, BORON COMPOUNDS. BORANES
BOVIDS
SEE MAMMALS. ARTIODACTYLA, CAHLE*
BOVINE SERUM ALBUMIN
SEE ALBUMINS, SERUM ALBUMIN BOVINE
BRADYCARDIA
SEE HEART DISORDERS. ARRHYTHMIA, BRAOYCARDIA
BRADYKININ
SEE PEPTIDES, VASOACTIVE PEPTIDES, KALLIDIN 9
BRADYKININ-ASSOCIATED HYPERTENSION
SEE CARDIOVASCULAR DISORDERS, HYPERTENSION
(SYSTEMIC), KININS-BRADYKININ-KALLIKREIN-
ASSOCIATED
BRAIN
SEE ALSO CEREBROVASCULAR SYSTEM
SEE ALSO CEREBROVASCUUR SYSTEM, CEREBRAL
CIRCUUTION
SEE ALSO NERVOUS SYSTEM CENTRAL
SEE ALSO PITUITARY GLAND
SEE ALSO SENSE ORGANS
ROlHL-10384-13 Blood How and nucleotide metabolism
(animals)
** POlHL-14388-07 0207 Regulation ol the circulation in
pathological states - Brain and renin-angiotension
interaction in spontaneous hypertension (rats)
R01HL-I8007-05 Neural mechanisms controling motor act
ol breathing (cats, human)
ROlHL-21471-02 Structurelunction studies on actin and
myosin (human, protozoa, rabbits, cattle)
** ROlHL-21969-01 Prevention of myocardial hypoxia during
bypass (rats, mice, squirrels)
R0)HL-22088-02 Metabolic basis for diabetic
microangiopathy (cattle)
BRAIN, AUDITORY CORTEX
** POlHL-08899-14 0052 Tolerance to respiratory gases in
health and disease - Oxygen effects on auditory and
vestibular function (human, guinea pigs)
BRAIN, BASAL GANGLIA, CAUDATE NUCLEUS
POlHL-14388-07 0151 Regulation of the circulation in
pathological states - Catecholamine release in potassium
ion-free contractures in the caudal artery
POlHL-14388-07 0152 Regulation of the circulation in
pathological states - Ion flux alterations in caudal artery in
SHR
** POlHL-18974-03 0009 Experimental neurogenic
hypertension program - Biochemistry ol brain tyrosine
hydroxylase (rats)
ROlHL-201 94-01 Brain catecholamines in control ol blood
pressure (rats)
BRAIN, BRAIN STEM
POlHL-06835-17 0060 Cardiovascular disease -
Ventricular performance experimental models of arterial
hypertension (rats, dogs)
POlHL-07896-15 0008 Environmental biomedical research
program - Otologic studies under hyperbaric conditions
(human, animals)
POlHL-10342-13 0019 The integrated function of
respiration and circulation - Cerebral circulation and
metabolism (dogs)
ROlHL-13187-09 Central neural control ol cardiovascular
lunction (cats)
POlHL-13851-16 Cyclotron produced isotopes in biology
and medicine (human, animals)
** ROlHL-13888-15 Regulation ol respiration
ROlHL-16648-16 Integrated control ol cardiovascular
activity (cats)
** POIHL 16878-05 0003 Control of ventilation in health
and disease - Brain stem respiratory neurons in response
mechanical/chemical loading (animal)
POlHL-16878-05 0004 Control of ventilation in health
and disease - Neurotransmitters in the respiratory system
(cats)
'Excludes routine methodology OR covere only general projects which preclude indexing at the specific level.
••Onented significantly to above subject.
BRA
NOIHl 1/90/04 llrain i«(ulilion ol caiditr tiihylhrnia
(pi|i citi. rilt)
POIHI 189/4 03 0001 liperimintal nturo|anic
hypertention progiim Cantial naural tytlamt r«fulttin|
■ rtariAl pre\iur« (rabbiti)
P50H1 I9IB/0? 0011 Pgdiitiic pulmonary SCOR Hyalint
membrane disease (lUcIt ol hypoiit and hyparcapnii on
developing nervous system (monkey, human)
ROIHL 20194 01 Brain catecholamines in control ol blood
pressure (rats)
" ROIHI 705/4 01 Brain slam integration ol chamoracaplof
activity (cats)
" ROIHI 20800 17 Neural basil ol ratpiralory and
vasomotor activity (cats)
ROIHL 21257 02 Breathing in sleep Airway control and
blood gases (cats)
R23HL 21914 01 Studies ol vasomotor control (rati)
" R0IHL224I801 Neural control ol cardio respiratory
lunction (cats)
BRAIN, CENTRAL SPACES
SEE ALSO NERVOUS SYSTEM CENTRAL. CEREBROSPINAL
FLUID
POIHL 14388 07 0207 Regulation ol the circulation in
pathological states Brain and renin angiotension
interaction in spontaneous hypertension (rats)
ROIHL 2179901 Circumventricular sites ol pressor action
ol angiotensin II (rats)
BRAIN, CENTRAL SPACES, CEREBRAL
VENTRICLES
ROIHL 1932003 Angiotensin neuropharmacology
Relationship to sodium
BRAIN, CENTRAL SPACES, CHOROID PLEXUS
** POlHL-08899 14 0054 Tolerance to respiratory gases in
health and disease - Glucose transport across choroid
plexus (dogs)
ROlHL-1932003 Angiotensin neuropharmacology-
Relationship to sodium
BRAIN, CEREBELLAR CORTEX, PURKINJE CELLS
POlHL-0789615 0008 Environmental biomedical research
program - Otologic studies under hyperbaric conditions
(human, animals)
BRAIN, CEREBELLAR NUCLEI
POlHL-16910-05 0007 Regulation ol the peripheral
circulation - CNS~Behavioral inlluences on circulation
(baboons)
** R23HL-22747-01 Cardiodynamics and hypertension under
cerebellar control (dogs)
BRAIN, CEREBELLUM
ROlHL-09913-13 Cerebral veins -Anatomic and radiologic
correlation (human)
POlHL-16910-05 0007 Regulation ol the peripheral
circulation - CNS-Behavioral inlluences on circulation
(baboons)
BRAIN, CEREBRAL CORTEX
SEE ALSO BRAIN, AUDITORY CORTEX
SEE ALSO BRAIN ELECTRICAL ACTIVITY
POlHL-07896-15 0030 Environmental biomedical research
program - Narcosis caused by inert gases at raised
pressures (human, animals)
" POlHL-07896-15 0049 Environmental biomedical research
program - Effects ol hyperbaric oxygen and pressure on
cerebral enzymes (rats)
POlHL-07895-15 0052 Environmental biomedical research
program - Effects ol hypoxia on cerebral lunction
ROlHL-11906-11 Comparative study of heart function
(cats, rats, hedgehogs, squirrels)
POlHL-14388-07 0193 Regulation of the circulation m
pathological states - Ontogenesis ol central nervous system
amines in hypertension (rats)
RO1HL-18601-01 Regulation ol neurotransmitter release by
adenosine (rats)
R0IHL-18932-03 Brain microcirculation observed in vivo
after trauma (mice)
ROlHL-20500-02 Diabetic human brain microvascular
basement membrane (human)
BRAIN, CEREBRAL CORTEX, MOTOR CORTEX
POlHL-06296-18 0007 Cardiovascular and pulmonary
adaptation to stress - Cardiovascular control during
isometric exercise (cats)
BRAIN, CEREBRUM
SEE ALSO BRAIN, LIMBIC SYSTEM
SEE ALSO BRAIN. LIMBIC SYSTEM. SEPTAL AREA
SEE ALSO BRAIN LESIONS SUR"" ' "
POlHL-14388-07 0179 Regulation ol 1,,^ .,,.,.u,o ,. ,
pathological states - Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
** POlHL-14388-07 0180 Regulation ol the circulation in
pathological states - Regulation of cerebral blood flow
(dogs, monkeys)
** ROlHL-19053-03 Vascular anatomy ol the telencephalon
(human)
ROlHL-21799-01 Circumventricular sites ol pressor action
ol angiotensin II (rats)
Icontd)
M Grant has subprojects descnbing specific research aspects.
See Appendix lor investigator's name and grant number
BRA
BRAIN, CEREBRUM, FRONTAL LOBE
ROlHL-09913-13 Cerebral veins-Anatomic and radiologic
correlation (human)
BRAIN, CEREBRUM, HIPPOCAMPAL FORMATION
ROlHL-09913-13 Cerebral veins-Anatomic and radiologic
correlation (human)
R01HL17800-04 Pulmonary reflexes -Central pathways
(cats, dogs, rabbits)
BRAIN, CEREBRUM, OCCIPITAL LOBE
ROlHL-09913-13 Cerebral veins-Anatomic and radiologic
correlation (human)
BRAIN, CEREBRUM, ORBITAL GYRI
ROlHL-02888 22 Interrelationships of circulation and
respiration (opossum, cats)
BRAIN, CEREBRUM, PARIETAL LOBE
ROlHL-09913-13 Cerebral veins-Anatomic and radiologic
correlation (human)
BRAIN, DRINKING REGULATORY CENTERS
POlHL-14388-07 0156 Regulation of the circulation in
pathclogical states - Blood pressure with drinking to
intracranial angiotensin II injections (rats)
BRAIN, HYPOTHALAMUS
SEE ALSO PITUITARY DIENCEPHALON (HORMONES)
ROlHL-02888-22 Interrelationships of circulation and
respiration (opossum, cats)
ROlHL-06736-18 Biogenic-mechanical factors in
microcirculation (rats, gerbils)
POlHL-08682-15 0006 Regulation of the cardiovascular
system - Cardiovascular studies of mammalian hibernators
(sciuromorpha)
POlHL-08682-15 0017 Regulation of the cardiovascular
system - Neurally induced cardiac dysrhythmias (dog)
POlHL-08682-15 0022 Regulation of the cardiovascular
system - Blood pressure responses and preganglionic
sympathetic outflow (cat)
POlHL-10342-13 0019 The integrated function of
respiration and circulation - Cerebral circulation and
metabolism (dogs)
ROlHL-13454-08 Behavioral stress and cardiomyopathy
(monkeys, cats)
P01HL-1438807 0193 Regulation of the circulation in
pathological states • Ontogenesis of central nervous system
amines in hypertension (rats)
** ROlHL-14560-07 Hypertension produced by sympathetic
dysfunction (human, rats)
** ROlHL-15307-06 Central nervous control of renin and
blood pressure (dogs)
ROlHL-1631505 Analysis of interaction between CNS
vasomotor systems (cats, rats)
ROlHL-16648-16 Integrated control of cardiovascular
activity (cats)
POlHL-1691005 0007 Regulation of the peripheral
circulation - CNS-Behavioral influences on circulation
(baboons)
** R01HL17907-04 Brain regulation of cardiac arrhythmia
(pigs, cats, rats)
ROlHL-1808503
monkeys)
ROIHL- 1860 1-01
adenosine (rats)
R01HL19144-03 Contraceptive steroids and experimental
hypertension (rats)
R01HL19209-03 Role of ADH in experimental renal
hypertension (dogs, rats)
ROIHL 20194-01 Brain catecholamines in control of blood
pressure (rats)
" ROlHL-22411-01 Neuroendocrine involvement in
hypertension (rats)
BRAIN, LIMBIC SYSTEM
SEE ALSO BRAIN, CEREBRUI^, HIPPOCAMPAL FORMATION
P01HL18974-03 0012 Experimental neurogenic
hypertension program • Immunohistochemistry of central
monoamine neurons (rats)
BRAIN, LIMBIC SYSTEM, SEPTAL AREA
** P01HL18974-03 0011 Experimental neurogenic
hypertension program • Biochemistry and regulation of
brain tryptophane hydroxylase (rats)
BRAIN, MEDULLA OBLONGATA
SEE ALSO BRAIN, RESPIRATORY CENTER
POlHL-08805-15 0046 Regulation of ventilation and
pulmonary circulation - Sites and modes of interaction of
peripheral and central chemoreccptors
ROlHL-13841 16 Respiration during altitude
acclimatization (goats, dogs, rats, rabbits)
POIHL 1498507 0009 Adaptation to hypoxia ■ Influence
of chemosensitivity on control of breathing during sleep
(human, dogs)
ROlHL-15392-06 Autonomic and circulatory actions of
anesthetics (dog, cat, rabbit, monkey)
ROlHL'16648-16 Integrated control of cardiovascular
activity (cats)
ROIHL- 1768906 Neurophysiologic studies of respiratory
control (cats)
P01HL18974-03 0001 Experimental neurogenic
hypertension program - Central neural systems regulating
arterial pressure (rabbits)
Neural factors in atherogenesis (squirrel
Regulation of neurotransmitter release by
74
BRAIN, MEDULLA OBLONGATA, AREA
POSTREMA
ROIHL 22617-01 Angiotensin, hypertension and the CNS
(sheep)
BRAIN, MEDULLA OBLONGATA, SOLITARY
TRACT NUCLEUS
POlHL-14388-07 0193 Regulation of the circulation in
pathological states - Ontogenesis of central nervous system
amines in hypertension (rats)
POlHL-18974-03 0006 Experimental neurogenic
hypertension program - Model of sustained arterial
hypertension (cats)
POlHL-18974-03 0008
hypertension program
(rats)
Experimental neurogenic
Monoamines and hypertension
BRAIN, MESENCEPHALON
POlHL-14388-07 0183 Regulation of the circulation in
pathological states - Vasopressin in cardiovascular
regulation (dogs, rats)
ROlHL-17903-03 Regional circulatory responses to hypoxia
(rats, cats, rabbits)
BRAIN, MESENCEPHALON, COLLICULUS
INFERIOR
ROlHL-19394-03 Biochemistry and regulation of taurine in
the heart (rats, guinea pigs, cats)
BRAIN, MESENCEPHALON, RAPHE NUCLEUS,
DORSAL
** POlHL-18974-03 0011 Experimental neurogenic
hypertension program - Biochemistry and regulation of
brain tryptophane hydroxylase (rats)
POlHL-18974-03 0012 Experimental neurogenic
hypertension program - Immunohistochemistry of central
monoamine neurons (rats)
BRAIN, PONS
** POlHL-08682-15 0037 Regulation of the cardiovascular
system - Central nervous regulation of cardiopulmonary
mechanisms (cats)
POlHL-14388-07 0183 Regulation of the circulation in
pathological states - Vasopressin in cardiovascular
regulation (dogs, rats)
POlHL-16878-05 0003 Control of ventilation in health
and disease - Brain stem respiratory neurons in response
mechanical/chemical loading (animal)
ROlHL-17689-06 Neurophysiologic studies of respiratory
control (cats)
BRAIN, PONS, TRIGEMINAL NUCLEUS (SPINAL)
** POlHL-18974-03 0001 Experimental neurogenic
hypertension program - Central neural systems regulating
arterial pressure (rabbits)
BRAIN, PROSENCEPHALON (GENERAL)
** ROlHL-224 18-01 Neural control of cardiorespiratory
function (cats)
BRAIN, REGULATORY CENTERS (GENERAL)
POIHL- 143 88-07 0229 Regulation of the circulation in
pathological states - Mechanism of postural hypotension
(human)
BRAIN, RESPIRATORY CENTER
SEE ALSO RESPIRATORY SYSTEM REFLEXES
POlHL-11678-11 0009 Cardiovascular dynamics and their
control - Control of respiration (cat. human)
** ROlHL-13888-15 Regulation of respiration
ROlHL-14102-07 Human physiology at 5360 meters-
Mountain environment
R01HL15659-05 Dynamic isolation studies of control of
respiration (human)
** ROlHL-16022-05 Determinants of the ventilatory response
to hypoxia (goats, cats)
** ROlHL-16430-05 Neural control of respiration (cats)
POlHL-1687805 0003 Control of ventilation in health
and disease - Brain stem respiratory neurons in response
mechanical/chemical loading (animal)
" POlHL-16878-05 0004 Control of ventilation in health
and disease - Neurotransmitters in the respiratory system
(cats)
ROlHL-177 15-04 Respiratory muscle afferenfs In
respiratory control (cats)
** ROlHL-17800-04 Pulmonary reflexes-Central pathways
(cats, dogs, rabbits)
** P50HL-1919002 0006 Pulmonary SCOR -Pathophysiology,
management of IRDS ■ Asphyxia-Respiratory control (dogs)
ROlHL-205 74-03 Brain stem integration of chemoreceptor
activity (cats)
** ROlHL-20800-17 Neural basis of respiratory and
vasomotor activity (cats)
R23HL-21405-01 Respiratory muscles in regulation of
infant breathing (human)
BRAIN, RETICULAR FORMATION
POlHL-10342-13 0019 The integrated function of
respiration and circulation ■ Cerebral circulation and
metabolism (dogs)
ROlHL-21532-02 Cardiovascular homeostasis and learning
(frogs, rats, human)
BRA
BRAIN, SUBCORTICAL STRUCTURES
POlHL-07896-15 0029 Environmental biomedical research
program Oxygen-helium diving resulting in high pressure
nervous syndrome (human, animals)
BRAIN, THALAMUS
** ROlHL-22732-01 Central organization of cardiac afferent
nerves (cats, monkeys)
BRAIN, VISUAL PATHWAYS
** POlHL-07896-15 0051 Environmental biomedical research
program - Relationships of retinal circulation to disease
(rabbits)
.** POlHL-08899-14 0047 Tolerance to respiratory gases in
health and disease - Oxygen effects on visual function
(human)
BRAIN CELLS
ROlHL-04457-20 Cellular aspects of active transport (fish,
rabbits, anurans, turtles)
BRAIN CIRCULATION DYNAMICS
SEE CEREBROVASCULAR SYSTEM. BRAIN CIRCULATION
BRAIN CONCUSSION
SEE BRAIN INJURY
BRAIN CONTROL
SEE PSYCHOLOGY, BRAIN CONTROL
BRAIN DEATH
SEE DEATH, CEREBRAL
BRAIN DISORDERS
SEE ALSO CEREBROVASCULAR DISORDERS
SEE ALSO CONGENITAL ABNORMALITIES, BRAIN (GENERAL)
SEE ALSO NERVOUS DISORDERS, MYELINOPATHIES
(GENERAL)
SEE ALSO NERVOUS DISORDERS CENTRAL (GENERAL)
SEE ALSO NEUROMOTOR DISORDERS, PARKINSON'S DISEASE
SEE ALSO PSYCHOLOGY ABNORMAL, MENTAL DISORDERS
(GENERAL)
POlHL-13851-16 Cyclotron produced isotopes in biology
and medicine (human, animals)
BRAIN DISORDERS, BRAIN EDEMA
P01HL06285-18 0147 Cardiovascular-respiratory
physiology and biochemistry - Metabolic regulation of
cerebral microcirculation (cats)
ROlHL-16643-02 Fluorocarbon emulsions as artificial
blood (animals)
R13HL-20765-01 Eleventh Princeton Conference on
Cerebrovascular Disease (new jersey)
BRAIN DISORDERS, CEREBELLAR DISORDERS
ROlHL-09913-13 Cerebral veins-Anatomic and radiologic
correlation (human)
BRAIN DISORDERS, CEREBRAL ATROPHY
DIFFUSE, SENILE DEMENTIA
** POlHL-07896-15 0055 Environmental biomedical research
program - Cerebral blood flow by Xenon-133 inhalation
(human)
NOlHV-52971-06 Reexamination of Framingham heart
study cohort
BRAIN DISORDERS, EPILEPSY
SEE ALSO NEUROMOTOR DISORDERS, CONVULSIONS
ROlHL-19394-03 Biochemistry and regulation of taurine in
the heart (rats, guinea pigs, cats)
ROlHL-21756-11 Vascular disease-Cytochemistry and
ultrastructure (human, rats, mice, hamsters)
BRAIN DISORDERS CONGENITAL
SEE CONGENITAL ABNORMALITIES, BRAIN (GENERAL)
BRAIN EDEMA
SEE BRAIN DISORDERS, BRAIN EDEMA
BRAIN ELECTRICAL ACTIVITY
SEE ALSO BRAIN DISORDERS, EPILEPSY
POlHL-08899-14 0006 Tolerance to respiratory gases in
health and disease - Effects of extreme pressures of inert
gases in macaque monkey
** POlHL-08899-14 0013 Tolerance to respiratory gases in
health and disease - Oxygen and carbon dioxide effects
upon human brain metabolism
** POlHL-08899-14 0022 Tolerance to respiratory gases in
health and disease - Effect of inert gas and hydrostatic
pressures on physiological functions (monkey)
** P50HL-142 14-07 0032 Newborn lung center for hyaline
membrane disease - Evoked electroencephalographic
potential in infants with HMD (human)
POIHL 14388-07 0183 Regulation of the circulation in
pathological states - Vasopressin in cardiovascular
regulation (dogs, rats)
ROlHL-1643005 Neural control of respiration (cats)
ROIHL 17715-04 Respiratory muscle afferents in
respiratory control (cats)
** P50HL-19187-02 0011 Pediatric pulmonary SCOR-Hyaline
membrane disease - Effects of hypoxia and hypercapnia on
developing nervous system (monkey, human)
BRAIN INJURY
SEE ALSO INJURIES, HEAD AND NECK
** ROlHL-18932-03 Brain microcirculation observed in vivo
after trauma (mice)
(contd)
•Excludes routine mcthodokigy OR covers onty general projects which preclude indexing at the specific level.
**Onented significantly lo above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
Human ventilatoiy adaptation (also,
Reactions ot hemeproteins and oxygen
BRA
BRAIN INTERHEMISPHERIC ACTIVITY, CEREBRAL
DOMINANCE
PbONl I4.M4 0/ 0013 Nawboin lung center lor hyillne
membrane disease Developmental outcome ol children
who had HMD as infants
BRAIN ISCHEMIA AND HYPOXIA
Sn CCREBROVASCUIAR DISORDFRS. BRAIN ISCHEMIA AND
HYPOXIA
BRAIN LESIONS SURGICAL
** ROIHL 1790/04 Brain regulation ol cardiac arrhythmia
(pigs. cats, rats)
BRAIN LESIONS SURGICAL, CEREBELLECTOMY
ROIHL 09913 13 Cerebral veins Anatomic and radiologic
correlation (human)
BRAIN LESIONS SURGICAL, DECEREBRATION
POIHL 06296 18 0007 Cardiovascular and pulmonary
adaptation to stress Cardiovascular control during
isometric exercise (cats)
BRAIN MAPPING
ROIHI 21257 02 Breathing in sleep Airway control and
blood gases (cats)
BRAIN METABOLISM
ROIHL'02477 23 Biosynthesis and function of lipids
(microorganisms, rats)
•• P01HL08899-14 0055 Tolerance to respiratory gases in
health and disease Oxygen effects on organ functions -
Extension of tolerance
ROIHL'14020'06 Characterization of myosin from blood
platelets (rabbit)
P50HL 1421807 0018 Pulmonary SCOR-Newborn lung
center Whole body buffering in acute hypercapnia (dogs)
ROIHL 15469-06
dogs, rats)
ROIHL 1598006
(cattle)
ROlHL.16828-04 Gradient and transport of oxygen in
tissue and organs (mammals)
R01HL1856703 A routine diagnostic test for minimal
heart damage (human, rat)
*• POlHL-18974-03 0010 Experimental neurogenic
hypertension program - Biochemistry and regulation of
PNMT in brain (rats)
ROIHL 18994-03 Substance P-Occurrence, pharmacology
and physiology (mammals non-human, human)
P50HL-19190-02 0006 Pulmonary SCOR -Pathophysiology.
management of IRDS - Asphyxia-Respiratory control (dogs)
** P50HL-1919002 0007 Pulmonary SCOR-Pathophysiology.
management of IROS - Asphyxia-Cerebral metabolism (dog,
rat)
ROlHL-20194-01 Brain catecholamines in control of blood
pressure (rats)
ROlHL-20317-02 Procoagulant lipoproteins-Biochemistry
and bioactivity (goats, rabbits)
BRAIN NEOPLASMS
SEE NEOPLASMS OF BRAIN
BRAIN OSCIUOGRAPHY
SEE BRAIN ELECTRICAL ACTIVITY
BRAIN SCANNING
SEE BRAIN VISUALIZATION, BRAIN SCANNING*
BRAIN STEM
SEE BRAIN, BRAIN STEM
BRAIN STIMULATOR (PACEAAAKER)
SEE BRAIN STIMUUTORS ELECTRONIC
BRAIN STIMULATORS ELECTRONIC
R01HLI1153-12 Quantitation of flov» and solute flux in
microvessels (cats, rats)
POlHL-1273810 0042 Physiologic pharmacology and its
clinical applications - Centrogenic cardiac arrhythmias
(cats)
R01HL13454-08 Behavioral stress and cardiomyopathy
(monkeys, cats)
R01HL1456007 Hypertension produced by sympathetic
dysfunction (human, rats)
ROlHL-15562-05 Regulation of skeletal muscle blood flow
(dogs)
ROlHL-17907-04
(pigs, cats, rats)
R01HL18085 03
monkeys)
Brain regulation of cardiac arrhythmia
Neural factors in atherogenesis (squirrel
BRAIN TUMOR
SEE NEOPUSMS OF BRAIN
BRAIN VISUALIZATION, BRAIN SCANNING*
POlHL-04664-18 0009 Cardiovascular and lung dynamics
- Biological signal and image processing techniques (dogs)
ROlHL-0991313 Cerebral veins-Anatomic and radiologic
correlation (human)
** POlHL-13851-16 Cyclotron produced isotopes in biology
and medicine (human, animals)
*E>dudes routine me(hodok>gy OR covers only general projects which preclude Indexing
**Oneiited significantly to above subject.
75
BRAIN VISUALIZATION, ULTRASONIC
ECHOENCEPHAIOORAPHY*
ROIHI 16260 04 Oiwrluiinirnt of clinical cine ultrasound
rnrdiogiaphy
BRAIN WAVE DETERMINATION OF DEATH
SfF OfATH. CFRFBRAl
BRAN, DIETARY
SEE NUTRITION. DIETARY CONSTITUENTS, DIETARY RESIDUES
FIBERS
BRANCHED CHAIN AMINO ACIDS
SFF AMINO ACIDS, BRANCHED CHAIN AMINO ACIDS
BRAZIL
SEE GEOGRAPHICAL SITES, S AMERICA, BRAZIL
BREAST NEOPLASMS
SEE NEOPLASMS OF REPRODUCTIVE SYSTEM, BREAST
NEOPLASMS
BRETYLIUM
SEE PHENYULKYUMINES, BENZYLAMINES. BRETYLIUM
lOSYWTE
BROMINE RADIOISOTOPES
SEE RADIOISOTOPES, BROMINE
BROMOCH LOROTRIFLUOROETHANE
SEE HALOALKANES, HALOTHANE
S-BROMODEOXYURIDINE
SEE HALOPYRIMIDINE NUCLEOSIDES, HALOURACIL
NUCLEOSIDES, 5 BROMODEOXYURIDINE
BROMSULPHTHALEIN
SEE BENZOFURANONES, PHTHALIOES, BROMSULPHTHALEIN
BRONCHI
SEE RESPIRATORY SYSTEM, BRONCHI
BRONCHIAL ASTHAAA
SEE HYPERSENSITIVfTY, RESPIRATORY HYPERSENSITIVITY,
ASTHMA
BRONCHIAL CIRCULATION
SEE RESPIRATORY CIRCUUTION, BRONCHIAL CIRCULATION
BRONCHIAL DISORDERS (GENERAL)
SEE RESPIRATORY DISORDERS, BRONCHIAL DISORDERS
(GENERAL)
BRONCHIAL MUCUS
SEE RESPIRATORY SYSTEM, BRONCHIAL MUCUS
BRONCHIAL NEOPLASMS (GENERAL)
SEE NEOPLASMS OF RESPIRATORY SYSTEM, BRONCHIAL
NEOPLASMS
BRONCHIECTASIS
SEE RESPIRATORY DISORDERS, BRONCHIECTASIS
BRONCHIOLE
SEE RESPIRATORY SYSTEM, BRONCHIOLE
BRONCHITIS ACUTE
SEE RESPIRATORY DISORDERS. BRONCHITIS ACUTE
BRONCHITIS CHRONIC AND EMPHYSEAAA
SEE RESPIRATORY DISORDERS, BRONCHITIS CHRONIC AND
EMPHYSEMA
BRONCHOCONSTRICTORS
SEE RESPIRATORY DRUGS, BRONCHOCONSTRICTORS
BRONCHO DILATORS
SEE RESPIRATORY DRUGS, BRONCHODILATORS
BRONCHOGRAPHY
SEE RESPIRATORY VISUALIZATION, BRONCHOGRAPHY*
BRONCHOMOTION
SEE RESPIRATORY FUNCTION. BRONCHOMOTION
BRONCHOPULMONARY LAVAGE
SEE RESPIRATORY ASSIST AND OXYGEN ADMINISTRATION,
PULMONARY LAVAGE
BRONCHOSCOPY
SEE RESPIRATORY VISUALIZATION, BRONCHOSCOPY*
BRONCHOSPASM
SEE RESPIRATORY DISORDERS. BRONCHOSPASM
BROWNING REACTION
SEE CHEMICAL REACTIONS. BROWNING REACTION
BRUSH BORDER MEMBRANES
SEE MEMBRANE. BRUSH BORDER MEMBRANES
BUFADIENOLIDES
SEE CARDIAC GLYCOSIDES AGLYCONES. BUFADIENOLIDES
BUFFERS
SEE ACIDS-BASES, BUFFERS
BUNDLE BRANCH BLOCK
SEE HEART DISORDERS, ARRHYTHMIA, HEART BLOCK.
BUNDLE BRANCH
at the specific level.
M Grant has subprojects descnbing specific research aspects.
See Appendix tor investigator's name and grant number.
CM
BUNOU OF HIS
SI I HIARI CONDUCTION SYSTFM. BUNDII OF Hl^
BURN THERAPY
SI I IHIHAPY. BURN IHIRAPY
BURNS
Sir INIUKItS. BURNS
BURNS, ELECTRICAL
SFf INIURIIS. BURNS. ElFCTRICAl
BURSA DEPENDENT IMMUNE SYSTEM
Sri IMMUNITY, HIJMORAI IMMUNIIY
BUTANOL, BUTYL ALCOHOL
SEE ALCOHOLS. BUTANOL
BUTYRIC ACID
SEE FAHY ACIDS. BUTYRIC ACID
BUTYRYLCHOLINESTERASE
SEE CHOLINE ESTERASES
BYPASS ARTERIOVENOUS ABNORMAL
SEE CARDIOVASCULAR DISORDERS. ARTERIOVENOUS SHUNTS
ABNORMAL
BYPASS ARTERIOVENOUS NORMAL
SEE CARDIOVASCULAR SYSTEM. ARTERIOVENOUS
ANASTOMOSIS NORMAL
BYPASS CARDIOVASCULAR ABNORMAL
SEE CONGENITAL ABNORMALITIES. CARDIOVASCULAR SHUNTS
ABNORMAL
BYPASS CARDIOVASCULAR SURGICAL
SEE CARDIOVASCULAR SURGERY. CARDIOVASCULAR SHUNTS
BYPASS COLLATERAL CIRCULATION NORMAL
SEE CARDIOVASCUUR SYSTEM. BLOOD SUPPLY, COLLATERAL
CIRCULATION
BYPASS CORONARY
SEE HEART REVASCULARIZATION, CORONARY BYPASS
BYPASS DUCTUS ARTERIOSUS EMBRYONIC
SEE CARDIOVASCULAR SYSTEM, DUCTUS ARTERIOSUS
EMBRYONIC
BYPASS HEART EXTRACARDIAC ABNORMAL
SEE CONGENITAL ABNORMALITIES, CARDIOVASCUUR SHUNTS
ABNORMAL
BYPASS HEART INTRACARDIAC ABNORMAL
SEE CONGENITAL ABNORMALITIES, HEART SEPTAL DEFECTS
BYPASS HEART-LUNG
SEE CARDIOVASCULAR SURGERY, CIRCULATORY ASSIST.
HEART-LUNG BYPASS
BYPASS HEART SURGICAL
SEE CARDIOVASCUUR SURGERY, CIRCUUTORY ASSIST.
HEART BYPASS SURGICAL
BYSSINOSIS
SEE RESPIRATORY DISORDERS, BYSSINOSIS
C
SEE IMMUNOLOGY, COMPLEMENT
CACHEXIA, PITUITARY
SEE PITUITARY GUND DISORDERS, HYPOPfTUITARISM
CADAVER (TISSUE)
SEE DEATH. CADAVER (TISSUE)
CADMIUM (COMPOUNDS)
SEE METALS, HEAVY METALS, CADMIUM
CAFFEINE
SEE PURINES, XANTHINES, CAFFEINE
CALCIFICATION INHIBITORS (CALCIUM
NEGATIVE BALANCE DRUGS)
P50HL-14230-07 0094 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Studies of atherosclerosis and regression
(monkeys)
P60HL15999-05 0021 Miami comprehensive sickle cell
center - Diphosphonates-Erythrocyte calcium loading,
maturation (human, chick embryo)
CALCIFICATION PATHOLOGIC
SEE CALCIUM (MINERAL) IMBAUNCES, CALCIFICATION
PATHOLOGIC
CALCIFICATION PHYSIOLOGIC
SEE CALCIUM (MINERAL) BAUNCE, CALCIFICATION
PHYSIOLOGIC
CALCINOSIS
SEE CALCIUM (MINERAL) IMBAUNCES, CALCIFICATION
PATHOLOGIC
CALCITONIN
SEE THYROID HORMONES, (THYROjCALCFTONIN
CALCIUM
ROlHL-00340-29 Electrolyte disturbance in cardio-renal
disease (human, dogs, rats)
ROlHL-02212-23 Coagulation ot blood (human)
(contd)
BRA
Micropuncture study of kidney function
Biocfiemistry of contractile proteins
ROlHL-02334-23
(rats, animals)
ROlHL-05883-18 0001 Reflex control of resistance and
capacitance vessels ■ Naturally occurring uasoactiue
substances and the vascular neuroetfectors (dog)
ROlHL-05883-18 0002 Reflex control of resistance and
capacitance vessels - Adenosine, adenine nucleotides and
vascular smootti muscle (dog)
ROlHL-05949-18 Biochemistry of muscle contraction (rats,
rabbits)
POlHL-06285-18 0195 Cardiovascular-respiratory
physiology and biochemistry - Thyroid thermogenesis and
sodium transport (rats)
POlHL-06308-18 0039 Mechanisms and therapy of
circulatory disease - ANS in regulation of electrophysiology-
Role of cyclic nulceotides (animals)
POlHL-06312-17 0051 Surgical cardiology ■ Diuretic
therapy on myocardial electrolyte composition and water
content (human)
POlHL-06314-17 0047 Immunologic mechanisms in
cardiovascular disease - Role of intravascular coagulation
(human, animals)
POlHL-06314-17 0054 Immunologic mechanisms in
cardiovascular disease • Physiology of cell communications
(mice, frogs, guinea pigs)
POlHL-0631417 0057 Immunologic mechanisms in
cardiovascular disease - Antigens in cardiovascular disease
(human)
ROlHL-09283-14 Pharmacology of molluscan hearts (also
rabbits)
ROlHL-09544-12
(animals)
* ROlHL-09906-13 0025 Membrane transport processes in
red blood cells - Mechanism of propranolol induced Ca-
dependent K efflux from human RBCs
ROlHL-10384-13 Blood flow and nucleotide metabolism
(animals)
ROlHL-1089712 Effects of hormones on cardiac
electrogenesis (rabbits, guinea pigs, dogs)
R01HL10942-09 Study of genetic hypertension in rats
POlHL-1 1307-12 0003 Biophysical studies in pediatric
cardiology - Cellular biophysics (animals)
POlHL-11351-12 0018 Cellular and molecular
mechanisms of myocardial function - Quantitative
localization of electrolytes in cardiac tissue
ROlHL-1 1906-11 Comparative study of heart function
(cats, rats, hedgehogs, squirrels)
POlHL-12157-11 0038 Functions and mechanisms of cell
membrane ion transport - Mechanisms and interactions of
gases and ions with bilayer membranes (human)
ROlHL-12486-10 Structure-function correlation in the
atrium (rabbits)
ROlHL-12528-10
ROlHL-12820-09
activation
ROlHL-12997-07 Myocardial defects induced by potassium
depletion (human, rats, cats)
ROlHL-13198-21 Blood coagulation -Physico-chemical
properties (human, cattle)
ROlHL-13257-09 Inhalation anesthesia on myocardial
metabolism (dogs, swine, human)
POlHL-13262-07 0016 Arterial wall in atherosclerosis -
Lipids in elastin preparations from atherosclerotic plaques
(human, animals)
ROlKL-13349-06 Analysis of activation process in heart
muscle (guinea pigs, rabbits, human)
ROlHL-14020-06 Characterization of myosin from blood
platelets (rabbit)
P50HL-14147-08 0003 Specialized center of research in
thrombosis - Surface thrombogenicity and phospholipid
vesicle physical properties
P50HL-14147-08 0013 Specialized center of research in
thrombosis - Mathematical models of blood coagulation
kinetics
P50HL-14230-07 0097 A/S SCOR -Lipids, atherosclerosis
and thrombosis - Studies of circulating platelet aggregates
(human)
•* POlHL-14388-07 0153 Regulation of the circulation in
pathological states - Subcellular distribution of calcium
(rats)
ROlHL-14461-08 Cardiac metabolism in heart failure
(rats)
ROlHL-14483-08 Energy conservation in heart
mitochondria (cattle, E coli, human)
ROlHL-14523-07 Generation and regulation of force in
smooth muscle (animals)
ROIHL 14614-07 Voltage control of contraction in heart
(sheep)
ROlHL-14820-07 Factors affecting physiology of biological
membranes (human)
ROlHL-14890-07 Platelet prostaglandins (human, rabbits)
ROlHL-14899-07 Mechanism and prevention of cardiac
arrhythmias (dogs)
R01HL-14903-07 A new index of cardiac contractility
(human, dogs, baboons)
ROlHL-15013-07 Lung oxidative metabolism and energy
production (rodents, rabbits)
ROIHL 15391-07 EPR studies on rotational motion of
myosin and actin
ROlHL-15498-06 Effects of physical training on heart
(rats)
NMR relaxation of liquid crystal systems
In vitro regulation of prothrombin
76
ROlHL-15512-06 Drug treatment of stenosing primate
atherosclerosis (rabbits, monkeys)
ROlHL-15728-06 The carbohydrate of the blood-clotting
glycoproteins (mammals)
ROlHL-15740-06 In vitro studies on heart cell function
(rats)
* ROlHL-15799-04 Effect of anesthetics on myocardial
function (cats)
POlHL-15832-06 0012 Chemical-structural predispositions
to lung injury - Contractile structures and contractility in
cells of lung respiratory tract
POlHL-15835-06 0001 Study of muscles related to heart
disease - Control of contraction-relaxation of heart and
muscle (rabbits, chickens)
POlHL-15835-06 0011 Study of muscles related to heart
disease - Energetics and mechanism of muscle contraction
(frogs, rabbits)
POlHL-15835-06 0012 Study of muscles related to heart
disease - Contraction and energetics of visceral and
vascular smooth muscles (rabbits)
POlHL-15835-06 0013 Study of muscles related to heart
disease - Cardiac bioenergetics (rats)
* POlHL-15835-06 0018 Study of muscles related to heart
disease Pharmacology of excitation coupling in muscle
(frog, barnacles)
POlHL-1 5835-06 0023 Study of muscles related to heart
disease - Cellular basis of the Frank-Starling curve (frogs,
rats)
ROlHL-15852-06 Vascular ion transport and hypertensive
mechanisms
ROlHL-15887-05 Enzymes of blood coagulation and
fibrinolysis (human)
ROlHL-16010-16 Cellular basis of cardiac contractility
(frogs)
POlHL-161 17-05 0002 Ion movements and membranes in
cardiovascular control - Fluorescence and excitation-
contraction coupling in heart (frogs)
** POlHL-161 17-05 0003 Ion movements and membranes in
cardiovascular control - Fast kinetic study of calcium
membrane interactions
** POlHL-161 17-05 0005 Ion movements and membranes in
cardiovascular control - Properties of isolated cell
membranes (rabbits, cats)
POlHL-161 17-05 0007 Ion movements and membranes in
cardiovascular control - Physiological and molecular
properties of ionophores (dogs, rabbits)
R01HH6346-09 Enzyme assay for blood clotting (human)
ROlHL-16421-08 Determinants of RBC deformability and
capillary flow (human, mice)
** ROlHL-16436-04
function (rats)
Role of calcium and thyroxine in heart
Contraction in heart and other striated
Intrarenal regulation of sodium
ROlHL-16606-11
muscles (frogs)
ROlHL-166 58-05
reabsorption
ROlHL-16660-06 Phospholipid-cholesterol and
phospholipid-protein interactions
ROlHL-16678-03 Fluorescent probe studies of heart
muscle proteins (rabbit, dog)
POlHL-16683-04 0002 Function and growth of cardiac
and skeletal muscle - Myosin, actin. ATP, interaction in
solution
ROlHL-16746-04 Design of ion-selective molecules
POlHL-16833-04 0014 Hemoglobin and red cell system in
hemoglobinopathies - Erythrocyte membrane damage in Hb
SS disease (human)
R01HL17322-04 Functional characteristics of smooth
muscle isolated from lung (animals)
ROlHL-17335-05 Contractile properties of hypertensive
arterioles (rats)
POlHL-17430-05 0005 Control of coagulation - The
activation of prothrombin (human, cattle, dogs)
ROlHL-17451-05 Digitalis effects on cardiac automaticity
mechanisms
ROIHL 17721-04 Effect of sex hormones on vascular
connective tissue (rats)
ROlHL-17729-04 Stimulus-response coupling in platelets
(human)
ROlHL-18032-03 Development of normal and myopathic
mammalian heart (hamsters)
ROIHL- 180 50-04 Mechanisms of cardiovascular
teratogenesis (chick embryo) k embryo)
ROlHL-18070-04 Regulation of intrapulmonary airways
and vessels (human, animals)
ROlHL-18148-04 Adrenal catecholamine secretion
ROlHL-18199-03 Effects of ions on vascular reactivity
P01HL-18208-04 0001 Center for the study of blood cell
rheology - Physiological basis of reversible erythrocyte
shape change (human, firefly)
POlHL-18208-04 0007 Center for the study of blood cell
rheology - RBC membrane protein (human)
* ROlHL-18255-04 Lipid-protein interactions and calcium
transport (models)
ROlHL-18280-03 Regulation of cardiac contractility and
metabolism (rats)
ROlHL-185 16-03 Atherosclerosis and the arterial
contractile proteins (pigs, rabbits)
ROlHL-18554-03 Taurine metabolism in mammalian heart
(rodents, cattle, swine)
ROlHL-18612-03
(cattle)
•Excludes routine methodotogy OR covers only general projects which preclude
"Onented sitnificanthi to above subiect
ROlHL-18737-03
ndexing at the specific level.
Thin filament control of heart contraction
Human erythrocyte membrane structure
CAL
POlHL-18827-02 0007 Platelet vessel wall interactions in
thrombogenesis - Biochemistry and role factor V in
thrombogenesis (human, cattle)
ROlHL-18834-04 Metal-dependent complex formation in
blood coagulation (human, cattle)
ROlHL-18852-03 Biochemical studies on the blood
coagulation process (human, cattle)
ROlHL-18937-03 Cyclic nucleotides and calcium in
platelets (human)
ROlHL-19012-03 Smooth muscle of resistance vessels in
hypertension (rats)
ROlHL-19072-03 Modification of tissue injury in
myocardial infarction (dogs, human)
ROlHL-19138-03 Contractile activation of skinned cardiac
cells (mammals)
ROIHL 19148-03 Myocardial organelle lipid structure and
function (dog. rat)
ROlHL-19252-02 Vascular connective tissue -Role in
atherosclerosis (rabbits)
R01HL-19324-02 Mechanisms of the inhibition of sickling
by DBA (human)
ROlHL-19378-03 Relation of mitochondrial changes to
cardiac failure (dogs, rats)
ROlHL-19414-03 Protection of myocardium during cardiac
surgery (dogs, cats, human)
R23HL-19501-01 Cardiac response to chronic metabolic
acidosis (rats)
POlHL-19737-02 0004 Cellular and molecular aspects of
respiratory physiology - Rapid reactions and erythrocyte
exchanges of blood during respiratory transport
ROlHL-19848-02 Contractile activation by rapid
temperature jumps (frogs)
ROlHL-19982-02 Blood coagulation-Protein-metal ion-lipid
interactions
ROlHL-20079-02 0001 Thromboresistant material - Active
and passive thromboresistant surfaces
ROlHL-20087-02 Developmental processes in pulmonary
hypertension (rats)
ROlHL-20161-02 Role of gamma-carboxyglutamic acid in
blood coagulation (human, cattle)
ROlHL-20190-02 Pathogenesis of cardiac hypertrophy
(dogs)
ROlHL-20196-02
muscle
ROlHL-20319-02
fibrin (human)
ROlHL-20369-03
ROlHL-20464-01
Regulation of coronary arterial smooth
Assembly, structure and interactions of
The effect of alcohol on the heart (rats)
Regulation of cardiac and skeletal
muscle contraction (mammals)
P01HL-20552-02 0003 The development and regression of
cardiac hypertrophy - Muscle mechanics of the
hypertrophied left ventricle (rats)
POlHL-20592-02 0004 Cell biology of cardiac and
skeletal muscle - Excitation, conduction and contraction-
Modelling in Purkinje fibers
POlHL-20592-02 0013 Cell biology of cardiac and
skeletal muscle - Sarcoplasmic reticulum in skinned
muscle cells (frogs)
ROlHL-20643-02 Analysis of heart cell contraction (rats)
ROlHL-20720-02 Myocardial protection during
cardiopulmonary bypass (dogs)
ROlHL-20725-02
transport
Mechanisms and cellular functions of ion
Coronary flow regulation by adenosine
ROlHL-20782-01
(rats, dogs)
ROlHL-20882-02 Interactions of plasma lipoproteins with
erythrocytes (Rhesus, human)
ROlHL-20902-02 Studies on marginal band system of
erythrocytes (amphibians, reptiles, fish)
ROlHL-20956-02 Early events following stimulation of
human platelets
POlHL-20984-02 0004 Cellular mechanisms in cardiac
hypertrophy - Myofibril accumulation in cardiac and
vascular muscle cells in hypertrophy
POlHL-20993-02 0007 Population dynamics of arterial
cells in atherogenesis - Interaction of lipoproteins in
hypercholesteremia (human, swine)
ROlHL-21 103-01 Parametric mechanical studies of
hypertensive arteries (dogs, rats)
ROlHL-2 11 39-02 Molecular biology of factor XIII (human)
ROlHL-21145-02 Response of atria to hyperosmolality-
Mechanisms (rabbits)
R23HL-21208-02 Structure-function relationships of human
factor VIII
ROlHL-21294-02 Voltage clamp of isolated cardiac
Purkinje cells (dogs)
ROlHL-21312-01 Sarcomere mechanics in disrupted
ventricular muscle (guinea pigs)
ROlHL-21329-02 Beta-receptor regulation and cardiac
sites of drug action (cat. guinea pig. rat)
ROlHL-21371-02 Energy loss microanalysis of myocardial
cations
R23HL-21488-01 Myosin-linked regulation in vertebrate
smooth muscle (calf aorta)
ROlHL-21493-02 Contractility in cardiac failure (hamsters)
ROlHL-21543-02 Structure-function relation of blood
clotting proteins (rabbits)
ROlHL-21820-01 Regulatory role of myosin in cardiac
hypertrophy (dogs)
ROlHL-21860-18 Factors influencing responses to
adrenergic drugs (guinea pigs. rats, cats)
(contd)
M Grant has subprojects describing specific research aspects.
See Appendix for Investigators name and grant number.
*MM^jUMmaatlrimyt^j
CAL
The spontaneously hypertensive kidney
ROIHI 21922 01 Trinjitnt cumnts Inductd by
ilrvphanthidin m lh( hatil
NOIHL 2I9/S 01 SludKS on normal ind abnotmal lacloi
IX (human, dois. cows)
ROIHL 2198801 Biochamistty ol human plalalet
chtmotKis
** ROIHI'2200801 Lett ventrivular calcium content and
contractility (rati)
ROIHI. 22039 02 Ion transport {n cardiac muscle (do|s.
rodants, cattle)
ROIHL 22088 02 Metabolic basis tor diabetic
microangiopathy (cattle)
** ROIHL 22137 02 Structure (unction pathology ot isolated
heart cells (mice, rats)
** ROIHL 22177 02 Mechanisms ot control ot pulmonary
smooth muscle (dogs)
ROIHL 22194 02 Allosteric function ol platelet contractile
proteins (human)
ROlHL-22216'02 Vascular mechanisms in renal
hypertension (dogs)
ROIHL'22281 01 Microprobe analysis and metabolite
levels ot ischemic mycardium (dogs)
ROIHL 2236101 Regulation of cardiac adaptation to
exercise (rats)
ROIHL'22401-01 Regulation ot tension and active state in
the heart
R01HL22426-01 Initiation ot the heartbeat-A voltage
clamp study (bullfrogs, rabbits)
ROIHL 22461 01 Cardiac tropomyosin and tropomyosin-
action interactions (rabbit)
R01HL-22500-01 Conversion of choline to
phosphatidylcholine in lung (rabbits, pigs)
ROlHL-22505-01 Molecular pathology of fibrinogen and
factor XIII (human, animals)
R01HL-22560-02 Stnjcture and motion of cilia
(Tetrahymena, mussels)
** POlHL-2261901 0005 Cellular mechanisms of heart
failure - Molecular mechanism of regulation of cardiac
muscle contraction (cattle)
** POlHL-22619-01 0006 Cellular mechanisms of heart
failure - Phosphorylation of contractile proteins in cardiac
muscle contraction (dogs, rabb
POlHL-22619-01 0008 Cellular mechanisms of heart
failure - Molecular mechanisms and differential contractile
responsiveness in VSM (dogs)
ROlHL-2277101 Thrombogenic phospholipid surfaces
(cattle)
** ROlHL-2283601
(rats)
ROlHL-22868-01 Presynaptic regulatory mechanisms in
hypertension (rats, dogs)
R01HL-22955-0I inetics of prothrombin activation
R23HL-22959-01 Heart development in inherited
cardiomyopathy (hamsters)
R01HL-229850I Properties and assembly of Z-disk
proteins (human, other species)
ROlHL-23010-01 Control and mechanism of platelet
aggregation (human)
ROlHL-23206-01 Repetitive exercise and cardiac
enlargement (dogs)
ROlHL-2339201 Membrane binding and transport of
calcium and potassium ionophores
ROlHL-23593-fll Mast cell granules -Structure and
secretion (rats)
ROlHL-23614-02 Pharmacology of relaxation in smooth
muscle (mollusks)
ROlHL-23615-01 Biochemistry of contractile proteins
(chicken, rabbit)
ROlHL-2399001 Role of phosphoprotein in cardiac
inotropic responses
ROlHL-23994-01 Biochemical properties ot human cardiac
myosin
CALCIUM (MINERAL) BALANCE (METABOLISM)
ROlHL-04512-19 Ultrastructural studies of capillary
permeability (rats, mice)
R01HL10018-11 Effect of aging on beating heart cells in
culture (rats)
** R01HL1218609 Calcium transients in striated muscle
and other cells (mammals, frogs)
R01HL1330209 Uptake and metabolism of lipids by the
liver (rats)
** R01HL13870-09 Control of myocardial sarcotubular
calcium stores (dogs)
P50HL14147-08 0014 Specialized center of research in
thrombosis ■ Theoretical models tor electrostatic effects in
blood clot formation
P50HL-14217-08 0057 Specialized center of research in
thrombosis Pharmacology-Platelet biochemistry (human,
animal)
P01HL14388-07 0167 Regulation of the circulation in
pathological states - Increased reactivity of artery vascular
muscle in spontaneously hypertensive rat
POlHL-14388-07 0172 Regulation of the circulation in
pathological states - cAMP-dependent protein kinase from
heart and vascular smooth muscle (guinea pigs)
ROIHL- 14820-0 7 Factors affecting physiology of biological
membranes (human)
P60HL-15157-07 0009 Comprehensive center for sickle
cell disease - Red cell membrane alterations during
sickling (human)
77
P60HL 15169 OS 0018 Support tor cento lor sickle cell
disease Studies on sickle cell disease (human, rati,
dogs)
" P60HL 1599905 0014 Miami comprehensive sickle cell
center Biochemical and morphological parameters of
sickle cells (human)
" ROIHI 16003 08 Sources and roles ol cdclum In smooth
muscle eiiitation (rats)
ROIHL 16/14 05 Fndolholial cell communication in
homeostasis (human, mammals)
P60HI 17265 04 0003 Community blood resource center
support Research Human (actor IX Role in intrinsic
clotting (also baboons, dogs)
P60HL 17269 04 0007 National heart and blood vessel
research and demonstration center Correlative studies of
experimental myocardial ischemia (dog)
•• P60HL 17269 04 0019 National heart and blood vessel
research and demonstration center Sarcoplasmic
reticulum (dog. rabbit, hamster, cat)
ROIHL 17597 05 Role of plasma lipoproteins in
atherosclerosis (swine, human)
P50HI 1764804 0023 Study of ischemic heart disease ■
Chemical mediators of inflammation in acute myocardial
infarction (mammals)
P50HL 17669 04 0006 Ischemic heart disease center
(SCOR) Studies of hypoxic, acidotic and ischemic cardiac
muscle (dogs)
P50HL 17669 04 0022 Ischemic heart disease center
(SCOR) Pathological studies of human and experimental
ischemic heart disease
P50HL 17670-04 0022 Study of ischemic heart disease -
Myocardial metabolism in hypoxia and recover (rabbit,
toad, dog)
P50HL-17682-04 0012 Study of ischemic heart disease ■
Pathology core laboratory (human)
P50HL 17682-04 0024 Study of ischemic heart disease -
Phosphorylation of cardiac contractile proteins during
ischemia (rat, guinea pig)
** ROlHL-18077-04 Smooth muscle cell organization and
Ca20 concentration control (chickens)
ROlHL-18824-03 Mechanisms of heart failure in
myopathic hamster
ROIHL 19000-03 Irreversible myocardial injury (rats)
ROlHL-19394-03 Biochemistry and regulation of taurine in
the heart (rats, guinea pigs, cats)
ROlHL-19399-02 Atherosclerosis -Early events and
regression factors (rats)
ROlHL-19633-02 Pathogenesis and pharmacology of lung
fibrosis (rats, rabbits)
ROlHL-20426-03
(dog. rat)
ROlHL-20558-02
and drugs
ROlHL-207 54-02
(rabbits)
ROlHL-21014-01
cardiac glycosides
** R23HL-212 13-01 A model for calcium homeostasis in
excitable tissue (marine worms)
R23HL-214 13-02 Structure and function of platelet
calcium-binding protein (human)
" R01HL-21670-0I Antiarrhythmic studies on 2-substifuted
aminoindenes (dogs)
** ROlHL-22135-01 Control of calcium fluxes across cardiac
membranes (dogs, rabbits, guinea pigs)
** ROlHL-22231-02 Modulation of calcium control of cardiac
myofibrils (rats)
ROlHL-22555-01 Structure and function of platelet
activating factor (rabbits, human)
R23HL-22575-01 Factors modifying cardiac digoxin effects
and content (dogs, cats)
R23HL-22984-01 Cyclic AMP dependent protein kinases in
hypertension (rat)
ROlHL-23138-01 Myocardial ischemia (dogs. rats, chick
embryo)
♦* ROlHL-231 53-01 Mechanisms of altered CA20 transport in
ischemic heart (dog. rabbit)
ROlHL-23161-01 0003 Biology of myocardial ischemia -
Phosphorylase coupling to myocardial sarcoplasmic
reticulum (dog)
R01HL-23249-0I Actin-myosin interaction in pulmonary
smooth muscle (cattle)
CALCIUM (MINERAL) BALANCE, CALCIFICATION
PHYSIOLOGIC
POlHL-10436-13 0008 A multidisciplinary study of
congenital heart disease - Physiologic consequences of
chronic hypoxemia (human)
" POlHL-11310-12 0101 Mechanisms of cardiovascular
disease - Molecular pathogenesis of vascular disease
CALCIUM (MINERAL) BALANCE, PHOSPHORUS
BALANCE (METABOLISM)
ROlHL-10503-13 Cardiac ion transport and ultrastructure
(rats, guinea pigs, rabbits)
CALCIUM (MINERAL) IMBALANCES,
CALCIFICATION PATHOLOGIC
** POlHL-11310-12 0101 Mechanisms of cardiovascular
disease - Molecular pathogenesis of vascular disease
ROlHL-15965-06 Experimental atherosclerosis and elastin
metabolism (chicks)
Myocardial function in diabetes mellitus
Cardiac electrophysiology-Effects of ions
Anesthetic-induced myocardial depression
Mechanism of the inotropic action of
'Excludes nwtine methodokigy OR covers only general projects which preclude indexing
"Onented signiflcantty to above subject.
at the specific level.
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
CAP
** ROIHL 20764 02 Flaslin and calcilicalion in pulmonary
and vascular disease (human, mammals)
CALCIUM (MINERAL) IMBALANCES,
HYPERCALCEMIA
ROIHI 00J40 29 lleclrolyte dislurbanci in cardio renal
disease (human, dogs, rats)
ROIHI 1660(05 Human and experimental renal diseaui
(animal'.)
ROIHI 22506 01 Hemodynamir.s of the clinical
hypertensions
CALCIUM (MINERAL) IMBALANCES,
PHOSPHORUS IMBALANCE
Stf Also MflABOIIC DISOROfRS INBORN.
HYPOPHOSPHAIASIA
ROIHL 00340 29 Lleclrolyte disturbance in cardio renal
disease (human, dogs, rats)
CALCIUM PUMP
SEE BIOLOGICAI TRANSPORT. ACTIVE TRANSPORT, ION
PUMPS, CALCIUM PUMP
CALCULI
SEE BILIARY TRACT DISORDERS, CHOLELITHS
CALF
SEE MAMMALS, ARTICDACTYU, CATTLE*
CAUITHRIX
SEE MAMMALS, PRIMATES, MONKEYS AND APES
(ANTHROPOIDS. NON-HUMAN), NEW V^ORLD MONKEYS
(PLATYRHINES)*
CALORIC CONTENT (OF FOODS)
SEE NUTRITION. DIETARY CONSTITUENTS. CALORIC CONTENT
CALORIC STIMULATION
SEE TEMPERATURE. HEAT. CALORIC STIMULATION
CALORIMETRY
SEE TEMPERATURE. HEAT, CALORIMETRY*
CAMERAS, SCINTILLATION
SEE RADIOASSAY, SCINTILLATION CAMERAS*
CANADA
SEE GEOGRAPHICAL SITES, N AMERICA. CANADA
CANCER
SEE NEOPLASMS
CANCER CELLS
SEE NEOPUSTIC CELLS
CANCER CHEMOTHERAPY
SEE NEOPLASTIC THERAPY, CANCER CHEMOTHERAPY
CANCER COMPLICATIONS, INFECTIONS
SEE NEOPUSMS. CANCER COMPLICATIONS OF. INFECTIONS
CANCER DIAGNOSIS
SEE NEOPLASMS DIAGNOSIS
CANCER EPIDEMIOLOGY
SEE NEOPLASTIC DISEASE EPIDEMIOLOGY-STATISTICS
CANCER GENETICS
SEE NEOPUSMS GENETICS
CANCER PATIENT CARE
SEE HEALTH CARE SERVICES. CASE FINDING AND OUTREACH
CANCER PATIENTS, DISEASE COMPLICATIONS
SEE NEOPLASMS, CANCER COMPLICATIONS OF
CANCER RADIOTHERAPY
SEE NEOPLASTIC THERAPY, CANCER RADIOTHERAPY
CANCER SURGERY
SEE NEOPUSMS SURGERY
CANCER SURVIVAL RATES
SEE NEOPUSTIC DISEASE EPIDEMIOLOGY-STATISTICS
CANNABIS
SEE ALKALOIDS, CANNABIS
CANNULATION
SEE ALSO CATHETERIZATION
** POlHL-06312-17 0042 Surgical cardiology - Right
ventricular assist device (sheep)
CAPILLARIES
SEE CARDIOVASCUUR SYSTEM, CAPILURIES
CAPILLARY BEDS
SEE CARDIOVASCUUR SYSTEM, CAPILURY BEDS
CAPRIDS
SEE MAMMALS. ARTIODACTYU. GOATS*
CAPSID AND CAPSOMERE, VIRAL
SEE VIRUS COMPONENTS. CAPSID AND ENVELOPE
CAPSULES
SEE DOSAGE FORMS
(contd)
CAR
CAPUCHINS
SEE MAMMALS, PRIMATES, MONKEYS AND APES
(ANTHROPOIDS, NON-HUMAN), NEW WORLD MONKEYS
(PLATYRHINES)*
CARBACHOL
SEE CHOLINE. CARBACHOL
CARBAMAMIDINE
SEE GUANIDINES
CARBAMATES
SEE ALSO PHENYUMINES, NEOSTIGMINE
POlHL-20993-02 0005 Population dynamics of arterial
cells in atherogenesis ■ Drugs ottier than hypolipidemic
drugs aflccting atherosclerosis (swine, rabbits)
CARBAMATES, URETHAN
P01HL-1373707 0002 Assisted circulation - U-shaped
mechanical auxiliary ventricle (dogs)
NOlHV'32959-10 Development of materials for heart assist
devices
CARBAMIDINE
SEE GUANIDINES
CARBAMOYlPHOSPHATEd-ASPARTATE
TRANSCARBAMYLASE
SEE TRANSCARBAMYLASES, ASPARTATE TRANSCARBAMYLASE
N-CARBAMYL AMINO ACIDS
SEE AMINO ACIDS, N-CARBAMYL AMINO ACIDS
CARBAMYL PHOSPHATE
N01HB-22919-08 Hemoglobin carbamylation in the
treatment of sickle cell anemia (human, dogs)
ROIHL 11822-10 Biophysical studies of macromolecular
interactions (microorganism, human)
** P60HL-15 169-05 0018 Support for center for siclde cell
disease - Studies on sickle cell disease (human, rats,
dogs)
R01HL-16375-04 Investigation of hemoglobin S properties
(human)
P01HL-16833-04 0009 Hemoglobin and red cell system in
hemoglobinopathies ■ Rheological studies of sicklcd cells
(human)
POlHL-1683304 0014 Hemoglobin and red cell system in
hemoglobinopathies - Erythrocyte membrane damage in Hb
SS disease (human)
CARBAMYLTRANSFERASES
SEE TRANSCARBAMYUSES
CARBOHYDRASES
SEE ALSO N-GLYCOSYLHYDROLASES
ROlHL-15474-06 Structure and function of the
antihemophilic factor (human, cattle)
** ROlHL-1788115 Biosynthesis and degradation of blood
group substances (human, animals)
R01HL-20301-02 Genetics of glycosyltransferases in
human blood
R23HL-21411-02 Control of extracellular lysosomal
hydrolase levels (rats)
CARBOHYDRASES, N-
ACETYLGLUCOSAMINIDASES
R01HL1815704 Subcellular events in atherosclerosis
(human, rabbits, calves)
ROlHL-20301-02 Genetics of glycosyltransferases in
human blood
ROlHL-20533-09 Pathogenesis of rheumatic fever (human,
rabbits)
CARBOHYDRASES, ALPHA-AMYLASE
N01HR-72921-01 Cystic fibrosis factor identification and
quantification (human)
CARBOHYDRASES, BETA-GALACTOSIDASE
P50HL-14153 07 0004 Johns Hopkins Lung Center-
Chronic diseases of airways Macrophage enzymes in lung
injury, inflammation and repair (rabbit)
R01HL18157-04 Subcellular events in atherosclerosis
(human, rabbits, calves)
R01HL18723-03 Genetic heterogeneity of acid lipase -
Atherosclerosis (human)
ROlHL-20104-03 Pulmonary granulomatous inflammations
(mice)
CARBOHYDRASES, ALPHA-GIUCOSIDASE
ROlHL-181 57-04 Subcellular events in atherosclerosis
(human, rabbits, calves)
CARBOHYDRASES, BETA-GLUCURONIDASE
R01HL13885-08 0008 Cystic fibrosis and pulmonary
disease - Pseudomonas specific activation of alveolar
macrophages (human, rabbits)
R01HL1907203 Modification of tissue injury in
myocardial infarction (dogs, human)
ROlHL-20104-03 Pulmonary granulomatous inflammations
(mice)
CARBOHYDRASES, HEXOSAMINIDASES
ROIHL 13722-08 Acid and alkaline lipases in aortas (rats,
rabbits, human)
R01HL19721-03 Lung inflammation -Lysosomal proteases
and liposomes (human, rabbits)
78
CARBOHYDRASES, HYALURONIDASE
POlHL-06370-17 0014 Cardiopulmonary and renal
pathology research center - Quantitative morphology In
cardiac disease (human, rats, dogs)
POlHL-14388-07 0219 Regulation of the circulation in
pathological states - Myocardial ischemia and infarction in
animals (dogs)
POlHL-14388-07 0221 Regulation of the circulation in
pathological states - Experimental myocardial infarction
(dogs)
P01HL1583206 0005 Chemical-structural predispositions
to lung injury - Pulmonary structure and stress-strain
relationships (rats)
P50HL-17669-04 0012 Ischemic heart disease center
(SCOR) ■ Circulatory assistance (human, dog)
ROlHL-19370-03 Coronary capillary exchange-The effects
of ischemia (dogs, sheep)
ROlHL-19782-02 Pharmacologic studies on the ischemic
heart (dogs)
ROlHL-20 199-02 Drug-induced alterations in infarct size
in the rat
ROlHL-21282-01 Dynamics of interstitial space in whole
animals (rats)
ROlHL-21684-02 0002 Radionuclide Infarct sizing and
therapy evaluation - Evaluating myocardial imaging agents
in global and regional ischemia (rabbits)
** ROlHL-22227-01 A new source of hyaluronidase and
anticoagulants (leeches)
CARBOHYDRASES, LYSOZYME
POlHL-082 14-15 0023 Chemical and biological properties
of lipids - Lipids in microorganisms and cell cultures
(hamsters, mosquitoes)
P50HL14 153-07 0004 Johns Hopkins Lung Center -
Chronic diseases of airways - Macrophage enzymes in lung
injury, inflammation and repair (rabbit)
POlHL-16748-05 0006 Cellular and immunological basis
of pulmonary diseases - Sarcoidosis -Studies with bronchial
lavage (human)
ROlHL-17895-04 Myocardial function and metabolism
following ischemia (rats)
ROlHL-18087-03 Development and regression of cardiac
hypertrophy (rats, rabbits)
ROlHL-18625-03 Organization of arterial ground substance
(cattle)
ROlHL-19237-03 Obstructive lung disease and alveolar
macrophages (human, animals)
ROlHL-20104-03 Pulmonary granulomatous inflammations
(mice)
POlHL-226 19-01 0007 Cellular mechanisms of heart
failure - Regulation of contractile protein levels in heart
muscle (rats)
ROlHL-23586-06 Pharmacologic control of hypersensitivity
phenomena (human)
CARBOHYDRASES, NEURAMINIDASE
POlHL-11351-12 0004 Cellular and molecular
mechanisms of myocardial function • Molecular
mechanisms of contractile function and differentiation
(animals)
POlHL-16851-04 0008 Human red cell membrane in
health and disease - Force balance in red cell interactions
(human)
POlHL-17382-05 0003 Chemical mediators of acute
pulmonary disorders - Chemical mediators relevant to
allergic reactions (human, guinea pigs)
ROlHL-19278-03 Ristocetin induced platelet aggregation
(human)
ROlHL-20533-09 Pathogenesis of rheumatic fever (human,
rabbits)
ROlHL-22738-01 Role of bioelectric potentials in platelet
adherence (bats, rats, hamsters)
CARBOHYDRATE BALANCE
SEE ALSO CARBOHYDRATES METABOLISM DISORDERS
** P01HL-08682 15 0020 Regulation of the cardiovascular
system - Hepatic metabolic basis of shock (rat)
POlHL-08682-15 0021 Regulation of the cardiovascular
system - Hypoglycemia in pathogenesis of shock (dog)
ROlHL-13630-08 Control of glycogen synthesis in heart
(cattle)
ROlHL-18923-02 Steroid-induced hyperlipidemia and
hypertension (human, rats)
CARBOHYDRATE BALANCE, BLOOD SUGAR
POlHL-0868215 0019 Regulation of the cardiovascular
system - Hepatic immunophysiology and host-defense in
shock (rat, dog, human)
POlHL-0868215 0020 Regulation of the cardiovascular
system - Hepatic metabolic basis of shock (rat)
** POlHL-08682-15 0021 Regulation of the cardiovascular
system - Hypoglycemia in pathogenesis of shock (dog)
P50HL-14141-05 0008 SCOR for atherosclerosis in
childhood - Core laboratory
ROlHL-16774-04 Genetic epidemiology of hyperlipemia
(Honolulu)
R01HL17479-04 Blood storage-The production of
cardiotoxic material (dogs, human, swine)
ROlHL-20393-03 Postsynthetic modifications of
hemoglobin in diabetics (human)
ROlHL-20447-03 Connective tissue and diabetic vascular
disease (human)
CAR
ROlHL-20483-03 Sterol balance and cholesterol absorption
in diabetics (human)
R01HL-20488-03 Cholesterol metabolism in diabetic man
R01HL-20508-03 Diabetes, hyperglycemia and
cardiovascular disease (human)
ROlHL-20522-03 Peripheral arterial disease in the diabetic
(human)
ROlHL-20539-03 Blood glucose, hemoglobin Ale. and
diabetic vascular disease (human)
CARBOHYDRATE BALANCE, GLUCOSE
TOLERANCE
** POlHL-06285-18 0151 Cardiovascular-respiratory
physiology and biochemistry - Microangiopathy in diabetic
and glucose intolerant children
** P50HL-14 138-05 0008 Center for research on
atherosclerosis - Core lipid laboratory (human)
P50HL-14138-05 0014 Center for research on
atherosclerosis • Core biostatistics laboratory
P50HL-14164-07 0041 A/S SCOR -Comparative and
experimental atherosclerosis - Nonhuman primate pediatric
atherosclerosis risk factor
P50HL-14236-05 0006 Prevention of premature
arteriosclerosis • Carbohydrate metabolism and
hypertriglyceridemia (human)
ROlHL-19175-03 Pituitary modulation of micro-and macro-
vascular disease (human, rats)
P50HL-19362-02 0013 A/S SCOR-Atherosclerosis in
nonhuman primates - Core laboratory-Lipid biochemistry
(baboons)
ROlHL-20418-03 Serum cholesterol binding reserve in
diabetes (human)
ROlHL-20508-03 Diabetes, hyperglycemia and
cardiovascular disease (human)
ROlHL-20535-02 Cardiovascular disease and evolving
diabetes mellitus (human)
ROlHL-20645-01 Etiology of myocardial infaction (human)
** ROlHL-21010-02 Glycemia, other traits and CV death in
40,000 persons
ROlHL-21416-02 Atherosclerosis in new modles of
diabetes mellitus
CARBOHYDRATE BALANCE, HYPERGLYCEMIA
SEE ALSO CARBOHYDRATES METABOLISM DISORDERS,
DIABETES
R01HL-00340-29 Electrolyte disturbance in cardio-renai
disease (human, dogs, rats)
P01HL06285-18 0149 Cardiovascular-respiratory
physiology and biochemistry - Microangiopathy in
prediabetic and diabetic subjects (human)
** POlHL-0628518 0150 Cardiovascular-respiratory
physiology and biochemistry - Basement membrane width
in non-diabetic hyperglycemia
ROlHL-09914-13 The myocardium in diabetes mellitus
(dogs, monkeys)
ROlHL-20381-03 Long-term study of diabetic vascular
disease (human)
ROlHL-20426-03 Myocardial function in diabetes mellitus
(dog, rat)
ROlHL-20460-03 Aortic histamine synthesis in diabetes
(rat)
ROlHL-20483-03 Sterol balance and cholesterol absorption
in diabetics (human)
** ROlHL-20508-03 Diabetes, hyperglycemia and
cardiovascular disease (human)
** RClHL-20539-03 Blood glucose, hemoglobin Ale, and
diabetic vascular disease (human)
" ROlHL-21010-02 Glycemia. other traits and CV death in
40.000 persons
ROlHL-21416-02 Atherosclerosis in new modles of
diabetes mellitus
CARBOHYDRATE BALANCE, HYPOGLYCEMIA
SEE ALSO PANCREATIC ISLETS DISORDERS.
HYPERINSULINISM
POlHL-08682-15 0020 Regulation of the cardiovascular
system - Hepatic metabolic basis of shock (rat)
** POlHL-08682-15 0021 Regulation of the cardiovascular
system - Hypoglycemia in pathogenesis of shock (dog)
CARBOHYDRATE BALANCE, HYPOGLYCEMIC
AGENTS
SEE ALSO PANCREAS HORMONES
ROlHL-18175-03 Drug taking for hypertension in a rural
community
CARBOHYDRATES
SEE ALSO GLYCOLIPIDS
SEE ALSO GLYCOPROTEINS
SEE ALSO NUCLEIC ACIDS
SEE ALSO NUCLEOSIDES
SEE ALSO NUCLEOTIDES
SEE ALSO NUTRITION, DIETARY CONSTITUENTS. DIETARY
CARBOHYDRATES
SEE ALSO OLIGOSACCHARIDES
SEE ALSO POLYSACCHARIDES
** ROlHL-02942-22 Biochemistry of cardiovascular connecth/e
tissue (human, cattle, primates)
POlHL-08214-15 0047 Chemical and biological properties
of lipids ■ High resolution liquid chromatography for the
analysis of biological substances
ROlHL-11511-10 Structure of ferritin and its role in iron
metabolism (horse, rats, human)
(contd)
•Excludes routine methodotogy OR covers only general projects which preclude
"Oriented signif icantly to above subject.
indexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for Investigator's name and grant number.
LJV^'ifuuuEnciCoC* .
CAR
79
ROIHL lj;37 09 Erythrocytii dunni early dcvilopmanl
(huinin, inlmtls)
PiOHl 14164 07 0040 A/S SCOR Compiratlva and
axparimtntal atharojclaiojii Coia angiochamistry
laboratoiy
SItuctute and tunclion of human plaimin
Antihamophilic factor (human)
Human dopamine beta hydroiylast (ilso
Conliol ot glycoien synlheiii in heart
Characteriiation of heart valve collagen
ROIHI 1SS3506
ROIHI. 168/2 04
ROIHL 1809S 04
cattle)
ROIHL 1859303
(human, pig)
ROIHL 194S6 03 Immunoglobulins associated with serum
hyperviscosity (human)
ROIHL'20092 02 Structural and biological properties ol
fibrinogen (human, rabbits)
R23HL 21393 01 Cardiac adaptation to aging and stress
(rats)
ROIHL 23618 01 Substrate metabolism In isolated
myocytes in shock (dogs. rats, guinea pigs)
CARBOHYDRATES, AMINO SUGARS
SEE ALSO SUGAR ACIDS. SIALIC ACIDS
** ROIHL 17796 04 Importance ot aminosugars in digitalis
activity (cats, rabbits)
ROIHL 1859303 Characterijation of heart valve collagen
(human, pig)
CARBOHYDRATES, GLYCOSIDES
SEE ALSO PUf«TS EXTRACTS, MEDICINAL PUNTS
SEE ALSO STEROIDS GLYCOSIDES
SEE ALSO TERPENES SAPONINS
R01HL0750213 Phytochemistry of the genus thalictrum
(dogs, plants)
ROIHL 14775 08 Mechanisms of drug action in vascular
smooth muscle (dog. rabbits)
CARBOHYDRATES, MONOSACCHARIDES
SEE ALSO HEXOSES
ROIHL- 18028-03 Absorption ot nonvolatile compounds
from the lung
R01HL-2I763-09 Heparin and heparan sulfate-Structure
and activity (beef, hog)
CARBOHYDRATES, PROTEIN BOUND
CARBOHYDRATES
SEE ALSO GLYCOPROTEINS
** ROlHL-02942-22 Biochemistry of cardiovascular connective
tissue (human, cattle, primates)
POlHL-11310-12 0099 Mechanisms of cardiovascular
disease - Carbohydrate chemistry of thy-1 and related
synaptosomal proteins
POlHL-1 1310-12 0103 Mechanisms of cardiovascular
disease - Heparin-Metabolism and function
POlHL-11310-12 0104 Mechanisms of cardiovascular
disease • Structure of connective tissue proteoglycans
(rabbits)
POlHL-1 1310-12 0105 Mechanisms of cardiovascular
disease - Biosynthesis of mammalian glycoproteins
(rabbits)
ROlHL-14844-06 Mucous glycoprotein in human respiratory
epithelium (also wheat)
ROlHL-14865-07 Biochemical studies on the pathogenesis
of emphysema (human, rats)
ROIHL- 156 15-06 Strocture-function studies of human
factor VIII/vWF
** ROlHL-15728-06 The carbohydrate of the blood-clotting
glycoproteins (mammals)
ROlHL-17194-03 Comparison of two inherited forms of
alpha-1-antitrypsin (human)
" ROIHL- 17783-04 Complex carbohydrates-Structure,
function, synthesis (swine)
R01HL-17898-03 Cell membranes and plasma lipoproteins
(human, swine)
R23HL-21369-02
bronchitis (rats)
ROlHL-21394-02
(rabbits)
R01HL-21626-0I
Tracheal mucin synthesis in experimental
Pulmonary angiotensin-converting enzyme
Proteoglycans of animal lung
parenchyma (cattle, pigs, rabbits)
ROlHL-21649-01 Biochemistry of lung proteoglycans
(mammals)
ROIHL-2323301 Pulmonary artery intermediate filament
structure (cattle)
CARBOHYDRATES, SULFOSUGARS
SEE ALSO POLYSACCHARIDES. SULFOPOLYSACCHARIDES
ROlHL-14844-06 Mucous glycoprotein in human respiratory
epithelium (also wheat)
CARBOHYDRATES, SULFOSUGARS, THIOSUGARS
ROlHL-21763-09 Heparin and heparan sulfate-Structure
and activity (beef, hog)
CARBOHYDRATES BIOSYNTHESIS
SEE ALSO HEXOSES. GLUCOGENESIS
POlHL-1 1310-12 0103 Mechanisms of cardiovascular
disease - Heparin-Metabolism and function
POlHL-11310-12 0104 Mechanisms of cardiovascular
disease - Structure of connective tissue proteoglycans
(rabbits)
•• POlHL-11310-12 0105 Mechanisms of cardiovascular
disease - Biosynthesis of mammalian glycoproteins
(rabbits)
*• ROIHL 1363008
(cattle)
•• P50HI 14236 05 0006 Prevention ol premature
arteriosclerosis Carbohydrate metabolism and
hypertriglyceridemia (human)
ROIHI 15728 06 The carbohydrate of the blood cloltlni
glycoproteins (mammals)
ROIHL 17783 04 Complex carbohydrates Structure,
function, synthesis (swine)
ROIHI 1/995 04 Cellular synthesis and release of
mucopolysaccharides (rabbits)
ROIHL 19/52 03 Phospholipid synthesis by fetal lung in
organ culture (rats)
ROIHL 20868 02 Regulation of glycoprotein biosynthesis in
lung (swine)
R23HL 22818 01 Biosynthesis of human respiratory
mucous ghrcoprotein (also dog)
R01HL23161 01 0003 Biology of myocardial ischemia -
Phosphorylase coupling to myocardial sarcoplasmic
reticulum (dog)
CARBOHYDRATES BIOSYNTHESIS,
GLYCONEOGENESIS
SEE ALSO HEXOSES, GLUCONEOGENESIS
ROIHL 15622-05 Computer simulation in cardiology (rats.
dogs)
ROIHL 204 76 03 Effects of diabetes on cardiac
performance (rat)
CARBOHYDRATES METABOLISM
SEE ALSO CARBOHYDRATE BAUNCE
SEE ALSO CARBOHYDRATES BIOSYNTHESIS
ROlHL-01813 25 Regulation of metabolism by drugs and
hormones (rats)
" POlHL-06312-17 0046 Surgical cardiology - The
relationship ol prostaglandins to heart disease
ROlHL-06950-17 Red cell metabolism (human,
vertebrates)
POIHL 0889914 0007 Tolerance to respiratory gases in
health and disease - Effects of high oxygen pressures on
visual function (human, animals)
ROlHL-10018-11
culture (rats)
R01HL-I2085-10
(human, rats)
ROlHL-12138-08
(rats, human)
ROlHL-12740-10
Effect of aging on beating heart cells in
Lipoproteincarbohydrate metabolism
Nutritional regulation of enzyme activity
Hypocholesterolemic agents-
Stereochemistry (rats)
ROlHL-1325709 Inhalation anesthesia on myocardial
metabolism (dogs, swine, human)
ROlHL-14526-07 Oral contraceptives and hypertension
(rats)
R01HL-I50 13-07 Lung oxidative metabolism and energy
production (rodents, rabbits)
** ROlHL-1 58 13-05 Cardiac anoxia-Protective effect of
carbohydrate (dogs)
ROlHL-16768-04 The sympathetic nervous system and the
arterial wall (rabbits, pigeons)
P50HL-17646-04 0009 Study of ischemic heart disease -
Regional metabolic derangements indicating ischemia
(rabbit, dog, human)
P50HL-191 71-02 0010 Pulmonary SCOR-Lung injury by
childhood infections - Metabolic pathways of normal and
injured respiratory cells
ROlHL-20408-03 Hyperlipidemia in diabetics during
muscular training (human)
ROlHL-20520-03 Protein modification-The key to diabetic
sequelae (human, animal)
ROlHL-214 16-02 Atherosclerosis in new modles of
diabetes mellitus
CARBOHYDRATES METABOLISM, GLUCOSE
METABOLISM
SEE ALSO CARBOHYDRATE BALANCE
SEE ALSO HEXOSES, GLYCOLYSIS
SEE ALSO TRICARBOXYLIC ACIDS, KREBS CYCLE
POlHL-06285-18 0135 Cardiovascular-respiratory
physiology and biochemistry - Beta-adrenergic agents and
fetal cardiovascular dynamics (lambs)
ROlHL-08506-15 Lipemia-carbohydrate and glyceride
metabolism (human, rats)
POlHL-08682-15 0020 Regulation of the cardiovascular
system - Hepatic metabolic basis of shock (rat)
" POlHL-1 13 10-12 0080 Mechanisms of cardiovascular
disease - Metabolism of the hypertrophied myocardium
(human)
ROlHL-12740-10 Hypocholesterolemic agents-
Stereochemistry (rats)
ROlHL-12879-09 0008 Pulmonary transport and
metabolism in vivo - Stop-flow technique for permeability
measurements
ROlHL-13405-09 Regulation of lipid metabolism in the
lung (rats)
ROlHL-13694-08 Capillary basement membrane in
cardiovascular disease (human, rats)
POlHL-13851 16 Cyclotron produced isotopes in biology
and medicine (human, animals)
R01HL14706-07 Fetal hearts in organ culture (mice)
POIHL-14985-07 0011 Adaptation to hypoxia -
Prostaglandins in the control of the pulmonary circulation
(animals)
•Odudes mitine raethodotogy OR covers only general projects which preclude indexing at the specific level
Onented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
CAR
POIHI 14985 07 0017 Adaptilwn to hrpoaii birKi
ellict ol hypoiK on pulmonary vttiulti >moolh muicl*
(rati, dogs)
P50HL 15061 0/ 0002 Ritpon-.< ol lung to iniury
Oxidative metaboliim. phoipholipid lynlhetit. and ictpon-.«
to toiini (rail)
P50H1 15092 0/ 0006 Immune and fibroin letpontt to
occupational enviionmenti Immunologic itudiai in
silicosis (human, rabbits, hamsters, guinea pigt)
ROIHI 1/43/03 Perfusion lung Role ol IraumatuM)
leukocytes (dogs, human)
P50HI 1/667 04 0012 Study ol i-.chemic heart diieau -
Biochemistry ol normal and ischemic heart Clycolyiii (rili)
P50HI 1/66/ 04 0040 Study of ischemic heart diM*M
Core biochemistry Cardiac metabolism (human)
*• ROIHL 1/895 04 Myocardial lunction and metabolism
following ischemia (ralsl
ROIHI 181/602 Eflnrt »( ih«.r,ifl hormone on cultured
(aidiac cells (i.i
P50HL 18318 03 00i3 i jii.jkciiesis and complications of
hypertension Cultured smooth muscle cells and
microvessel metabolism (mammals)
POIHI 19242 02 0001 Study ol vascular smooth muscle
Energy metabolism and protein turnover in vascular smooth
muscle (rats)
** ROIHL 20206 02 Carbohydrates nucleotides and adrenergic
interactions (rabbits, cats, rats)
ROIHL 20401-03 Relationship of insulin to catechol
cardiomyopathy (rabbit, pig)
ROIHL 20429 03 Study of effects of diabetes reactivity
(miniature pigs, rats)
"* R01HL21209-02 Alterations of metabohsm in ischemic
myocardium (swine)
ROIHL 22088-02 Metabolic basis for diabetic
microangiopathy (cattle)
ROlHL-2210102 Hormone substrate interaction in diabetic
myocyte (dogs, rats)
CARBOHYDRATES METABOUSM DISORDERS
SEE ALSO CARBOHYDRATE BALANCE
SEE ALSO METABOLIC DISORDERS INBORN. DISACCHARIDE
(OLIGOSACCHARIDE) INTOLERANCE
SEE ALSO METABOLIC DISORDERS INBORN. GLUCOSE-6-
PHOSPHATE DEHYDROGENASE DEFICIENCY
SEE ALSO METABOLIC DISORDERS INBORN. GLYCOGENOSIS
SEE ALSO METABOLIC DISORDERS INBORN. OBESIPf
HEREDITARY HYPERGLYCEMIC
SEE ALSO PANCREATIC ISLETS DISORDERS
** ROlHL-08506-15 Lipemia-carbohydrate and glyceride
metabolism (human, rats)
POlHL-12373-10 0006 Cardiopulmonary physiology and
pathophysiology - Fatty acid metabolism-Regulation,
implications (human, mammals, birds)
** ROlHL-12399-13 Specific fatty acids and cholesterol
metabolism (gerbils. rats)
R01HL-18776-04 Prevention of acute and fatal
cardiovascular disease (human)
ROlHL-19961-03 Management of hemosiderosis in
thalassemia (children, adults)
CARBOHYDRATES METABOLISM DISORDERS,
DIABETES
SEE ALSO CARBOHYDRATE BALANCE, GLUCOSE TOLERANCE
SEE ALSO CARBOHYDRATE BALANCE, HYPOGLYCEMIC AGENTS
SEE ALSO CARBOHYDRATES METABOLISM DISORDERS,
DIABETIC ANGIOPATHIES
SEE ALSO MHABOLIC DISORDERS INBORN, OBESITY
HEREDITARY HYPERGLYCEMIC
SEE ALSO PANCREATIC ISLETS DISORDERS
ROlHL-02063-23 Biochemistry and function of lipids and
cell membranes (human, yeast, animals)
ROlHL-02965-22 Metabolism of plasma lipoproteins (rats,
chickens, human)
ROlHL-04300-20 Fine structure of diseased glomeruli
(human, rats, dogs)
ROlHL-06221-17 Composition and structure of plasma
lipoproteins (human, turkeys, baboons)
" POlHL-06285-18 0149 Cardiovascular-respiratory
physiology and biochemistry - Microangiopathy in
prediabetic and diabetic subjects (human)
POlHL-06285-18 0150 Cardiovascular-respiratory
physiology and biochemistry - Basement membrane width
in non-diabetic hyperglycemia
POlHL-06314-17 0064 Immunologic mechanisms in
cardiovascular disease - Diabetic vascular disease (human,
rats, mice)
POlHL-0631417 0066 Immunologic mechanisms in
cardiovascular disease - Sensitization, cell-mediated
cytotoxicity, role of lymphocytes (human, mice)
POlHL-08214-15 0006 Chemical and biological properties
of lipids - Analysis and properties of lipids
R01HL-08659-I4 Myocardial performance and metabolism
in the newborn (sheep)
POlHL-0897414 0028 Natural and experimental
atherosclerosis - Geographic pathology of atherosclerosis
and coronary heart disease (human)
ROlHL-09914-13 The myocardium in diabetes mellitus
(dogs, monkeys)
'♦ POlHL-11678-11 0046 Cardiovascular dynamics and their
control - Regulation of aldosterone secretion and related
factors (dogs)
(coittd)
CAR
POlHL-12373-10 0012 Cardiopulmonary physiology and
pathophysiology ■ Biochemistry of the sympathetic nervous
system (rats! rabbits, pigeons)
ROlHL-12766-09 Structure-function relation of blood
vessels (rats, monkeys)
** ROlHL-12869-09 Arterial metabolism, diabetes and
atherogenesis (rats, rabbits)
ROlHL-13036-08 Coronary thrombosis -Effects on
myocardium and in vivo detection (dogs, monkeys)
ROlHL-13405-09 Regulation of lipid metabolism in the
lung (rats)
ROlHL-13654-08 Antilipemic regimes in peripheral
arteriosclerosis (human)
P50HL-14138-05 0015 Center for research on
atherosclerosis ■ Arterial wall -Intermediary metabolism,
enzyme activity and bioenergetics
P50HL-14236-05 0004 Prevention of premature
arteriosclerosis - Plasma lipoproteins (human, rats)
P50HL-14236-05 0006 Prevention of premature
arteriosclerosis - Carbohydrate metabolism and
hypertriglyceridemia (human)
ROlHL-14713-06 Hypothermia and the heart (bats, guinea
pigs)
ROlHL-15047-06 Digital computer analysis of the
electrocardiogram (human)
P50HL-15103-07 0001 A/S SCOR -Early natural history of
arteriosclerosis - Clinical research -Bogalusa heart study
(children)
ROlHL-15427-06 Secretion of plasma lipoproteins (rats)
ROlHL-15622-05 Computer simulation in cardiology (rats,
dogs)
ROlHL-15696-06 Mechanism and role of cyclic GMP in
heart (animals)
ROlHL-16219-05 Mechanisms of atherogenesis in chronic
uremia (human, rats)
P50HL1 7667-04 0012 Study of ischemic heart disease -
Biochemistry of normal and ischemic heart -Glycolysis (rats)
P50HL- 183 18-03 0002 Pathogenesis and complications of
hypertension - Core experimental animal facility (rats,
rabbits)
P50HL-18318-03 0014 Pathogenesis and complications of
hypertension Arterial metabolism and atherogenesis (rat,
rabbit)
POlHL-18645-03 0007 Biology of the artery wall and
atherosclerosis - Lipoprotein metabolism in subhuman
primates
ROlHL-18687-03 Pathophysiology of genetic
hypertriglycerinemias (human)
ROlHL-18705-03 Regulation of plasma triglyceride
metabolism (rats)
ROlHL-18938-03 Pulmonary fatty acid and phospholipid
metabolism (rats)
ROlHL-19175-03 Pituitary modulation of micro-and macro-
vascular disease (human, rats)
ROlHL-19467-03 Regulation of blood pressure (rats, dogs)
ROlHL-19644-03 Etiological factors in hypertension
(human, dogs, rats)
ROlHL-19839-09 Factors in youth predisposing to chronic
diseases (former college students)
** ROlHL-20381-03 Long-term study of diabetic vascular
disease (human)
** ROlHL-20388-03 Regulation of protein turnover in diabetic
heart (rat)
ROlHL-20391-03 Polydisperse LDL-Structure, metabolism
and function (human)
** ROlHL-20393-03 Postsynthetic modifications of
hemoglobin in diabetics (human)
** ROlHL-20397-03 VLDL-TG metabolism in diabetes mellitis
(human, rat)
** ROlHL-2039903 Vascular control in experimental diabetes
mellitus (dog)
** ROlHL-20401-03 Relationship of insulin to catechol
cardiomyopathy (rabbit, pig)
** ROlHL-20408-03 Hyperlipidemia in diabetics during
muscular training (human)
** ROlHL-20411-03 Platelet fatty acid metabolism in
diabetes (rat, rabbit, guinea pig)
" ROlHL-20418-03 Serum cholesterol binding reserve in
diabetes (human)
** ROltlL-20426-03 Myocardial function in diabetes mellitus
(dog, rat)
ROlHL-20428-03 The juvenile diabetic heart (human)
** ROIHL 20429-03 Study of effects of diabetes reactivity
(miniature pigs, rats)
•• ROlHL-20439-02 Effects of insulin on neurovascular
transmission (human, rats, rabbits, hamsters)
*• ROlHL-20446-02 Autonomic neuropathy in diabetic mice
(also rats)
** ROlHL-20447-03 Connective tissue and diabetic vascular
disease (human)
** ROlHL-20460-03 Aortic histamine synthesis in diabetes
(rat)
** ROlHL-20471-03 Atherosclerosis and diabetes mellitus
(human)
** ROlHL-204 76-03 Effects of diabetes on cardiac
performance (rat)
** ROIHL 20483-03 Sterol balance and cholesterol absorption
In diabetics (human)
•* ROlHL-20484-03 Effects of diabetes on cardiac function
and metabolism (rats)
** ROlHL-20488-03 Cholesterol metabolism in diabetic man
80
* ROlHL-20508-03 Diabetes, hyperglycemia and
cardiovascular disease (human)
* ROlHL-20517-03 Diabetes, somatotropin, factor VIII and
atherosclerosis (human, animal)
* ROlHL-20520-03 Protein modification-The key to diabetic
sequelae (human, animal)
* ROlHL-20522-03 Peripheral arterial disease in the diabetic
(human)
* ROlHL-20535 02 Cardiovascular disease and evolving
diabetes mellitus (human)
ROlHL-21010-02 Glycemia. other traits and CV death in
40,000 persons
* R23HL-21291-02 Renin-mineralocorticoid axis in
hypertensive diabetics (human)
R23HL-21320-02 Cyclic nucleotide metabolism in vascular
endothelium
'* ROIHL-214 16-02 Atherosclerosis in new modles of
diabetes mellitus
'* R01HL-21482-01 Cardiac function and metabolism in
diabetes (rats)
'* R23HL-21842-01 Control of sugar entry in normal and
diabetic heart (rats)
" ROlHL-21843-01 Ischemia, diabetes and the
microcirculation (rats, cats, hamsters)
** ROlHL-22053-02 The disordered lipid metabolism of
diabetes mellitus (chickens, mammals, human)
** ROlHL-22064-02 Glycogen metabolism in anoxic diabetic
myocardium (rats)
** ROlHL-22088-02 Metabolic basis for diabetic
microangiopathy (cattle)
** R01HL-22101-02 Hormone-substrate interaction in diabetic
myocyte (dogs, rats)
** ROlHL-221 06-02 Diabetic cerebral vascular structure and
function
** ROlHL-221 13-02 Micro/macrovasculature in healing of
foot lesions (human)
** ROlHL-221 15-02 Lipid-mobilization and diabetic
atherosclerosis (human)
** ROlHL-221 18-02 Microcirculation in patients with diabetes
mellitus
** ROlHL-22121-02 Oyslipoproteinemia in diabetes and
vascular disease (human)
** ROlHL-22123-02 The role of the red cell in diabetic
atherosclerosis (human)
ROlHL-22474-01 Cholesterol metabolism and
atherosclerosis (rats, human, rabbits)
ROlHL-22506-01 Hemodynamics of the clinical
hypertensions
** ROlHL-22581-02 Neurocirculatory control in diabetes
mellitus (human)
ROlHL-228 12-01 Regulation of hepatic production of HDL
(rats)
ROlHL-23602-01 Physiology of renin, aldosterone and
prostaglandin (human, rats, dogs)
ROlHL-236 18-01 Substrate metabolism in isolated
myocytes in shock (dogs, rats, guinea pigs)
NOlHV-121 56-10 Lipid research clinic
NO lHV-12 159-09 Lipid research clinic
NOlHV-229 16-16 Establishment of a lipid research clinic
CARBOHYDRATES METABOLISM DISORDERS,
DIABETES, INSULIN (RESISTANCE) TOLERANCE
SEE ALSO METABOLIC DISORDERS INBORN, OBESITY
HEREDITARY HYPERGLYCEMIC
** POlHL-06835-17 0024 Cardiovascular disease - Studies
on the obese spontaneously hypertensive rat
** ROlHL-08506-15 Lipemia-carbohydrate and glyceride
metabolism (human, rats)
ROlHL-196 73-03 Surgical aspects of shock and hypoxia
(dogs, monkeys, rats)
ROlHL-221 15-02 Lipid-mobilization and diabetic
atherosclerosis (human)
ROlHL-22123-02 The role of the red cell in diabetic
atherosclerosis (human)
CARBOHYDRATES METABOLISM DISORDERS,
DIABETES, JUVENILE
ROlHL-02942-22 Biochemistry of cardiovascular connective
tissue (human, cattle, primates)
P01HL-06285-18 0151 Cardiovascular-respiratory
physiology and biochemistry - Microangiopathy in diabetic
and glucose intolerant children
POlHL-09011-15 0001 A research and resource program
in blood - Genetic markers of human blood and gene
mapping (human)
** ROlHL-13632-08 Vascular changes in diabetes mellitus
(human)
ROlHL-20401-03 Relationship of insulin to catechol
cardiomyopathy (rabbit, pig)
ROlHL-20408-03 Hyperlipidemia in diabetics during
muscular training (human)
ROlHL-204 18-03 Serum cholesterol binding reserve in
diabetes (human)
** ROlHL-20428-03 The juvenile diabetic heart (human)
ROlHL-20446-02 Autonomic neuropathy in diabetic mice
(also rats)
ROlHL-20447-03 Connective tissue and diabetic vascular
disease (human)
** ROlHL-205 17-03 Diabetes, somatotropin, factor VIII and
atherosclerosis (human, animal)
** ROlHL-20539-03 Blood glucose, hemoglobin Ale, and
diabetic vascular disease (human)
CAR
ROlHL-22123-02 The role of the red cell in diabetic
atherosclerosis (human)
CARBOHYDRATES METABOLISM DISORDERS,
DIABETES, PREDIABETIC STATE
** POlHL-06285-18 0149 Cardiovascular-respiratory
physiology and biochemistry - Microangiopathy in
prediabetic and diabetic subjects (human)
ROlHL-13694-08 Capillary basement membrane in
cardiovascular disease (human, rats)
ROlHL-20535-02 Cardiovascular disease and evolving
diabetes mellitus (human)
CARBOHYDRATES METABOLISM DISORDERS,
DIABETES IN PREGNANCY
ROIHL 19752-03 Phospholipid synthesis by fetal lung in
organ culture (rats)
ROlHL-20535-02 Cardiovascular disease and evolving
diabetes mellitus (human)
CARBOHYDRATES METABOLISM DISORDERS,
DIABETIC ACIDOSIS
SEE ALSO KETONE BODIES
ROlHL-22581-02 Neurocirculatory control in diabetes
mellitus (human)
CARBOHYDRATES METABOLISM DISORDERS,
DIABETIC ANGIOPATHIES
SEE ALSO CARBOHYDRATES METABOLISM DISORDERS,
DIABETIC NEUROPATHIES
SEE ALSO CARBOHYDRATES METABOLISM DISORDERS,
DIABETIC RETINOPATHY
ROlHL-02942-22 Biochemistry of cardiovascular connective
tissue (human, cattle, primates)
** POlHL-03 174-23 0007 Mechanisms of acute vascular
reaction to injury - Healing of injured myocardium-Basal
lamina scaffold (human, rats, dogs)
** POlHL-06285-18 0149 Cardiovascular-respiratory
physiology and biochemistry - Microangiopathy in
prediabetic and diabetic subjects (human)
POlHL-06285-18 0151 Cardiovascular-respiratory
physiology and biochemistry ■ Microangiopathy in diabetic
and glucose intolerant children
** POlHL-06285-18 0152 Cardiovascular-respiratory
physiology and biochemistry - Diabetic microangiopathy by
organ and tissue culture (human)
** POlHL-06314-17 0064 Immunologic mechanisms in
cardiovascular disease - Diabetic vascular disease (human,
rats, mice)
ROlHL-12085-10 Lipoprotein-carbohydrate metabolism
(human, rats)
" ROIHL- 13632-08 Vascular changes in diabetes mellitus
(human)
** ROIHL- 13694-08 Capillary basement membrane in
cardiovascular disease (human, rats)
•* ROlHL-17932-04 Blood flow regulation in muscle (cats)
ROlHL-18977-03 Non-invasive diagnosis of peripheral
arterial disease (human, dogs)
ROlHL-19175-03 Pituitary modulation of micro-and macro-
vascular disease (human, rats)
** ROlHL-20381-03 Long-term study of diabetic vascular
disease (human)
ROlHL-20393-03 Postsynthetic modifications of
hemoglobin in diabetics (human)
** ROlHL-20400-03 Diabetic neuropathy and peripheral
vascular diseases (human, hamsters)
ROlHL-20411-03 Platelet fatty acid metabolism in
diabetes (rat, rabbit, guinea pig)
ROlHL-20428-03 The juvenile diabetic heart (human)
** ROlHL-20429-03 Study of effects of diabetes reactivity
(miniature pigs, rats)
ROlHL-20447-03 Connective tissue and diabetic vascular
disease (human)
** ROlHL-20500-02 Diabetic human brain microvascular
basement membrane (human)
ROlHL-20508-03 Diabetes, hyperglycemia and
cardiovascular disease (human)
** ROlHL-20517-03 Diabetes, somatotropin, factor VIII and
atherosclerosis (human, animal)
" ROlHL-20520-03 Protein modification-The key to diabetic
sequelae (human, animal)
** ROlHL-20539-03 Blood glucose, hemoglobin Ale, and
diabetic vascular disease (human)
** ROlHL-21039-02 Vascular lesions of diabetes in Oklahoma
Indians
R23HL-21320-02 Cyclic nucleotide metabolism in vascular
endothelium
ROlHL-21416-02 Atherosclerosis in new modles of
diabetes mellitus
ROlHL-21756-11 Vascular disease-Cytochemistry and
ultrastructure (human, rats, mice, hamsters)
** ROlHL-22064-02 Glycogen metabolism in anoxic diabetic
myocardium (rats)
** ROlHL-22101-02 Hormone-substrate interaction in diabetic
myocyte (dogs, rats)
ROlHL-22113-02 Micro/macrovasculature in healing of
foot lesions (human)
** R01HL-22115-02 Lipid-mobilization and diabetic
atherosclerosis (human)
** ROlHL-221 18-02 Microcirculation in patients with diabetes
mellitus
ROlHL-22123-02 The role of the red cell in diabetic
atherosclerosis (human)
(contd)
•Excludes routine melhodotogy OR covers only general projects which preclude i
'•Onented significantly to above subiect.
ndexing at the specific level.
M Grant has subprojeds describing specific research aspects.
See Appendix tor investigator's name and grant number.
CAR
CARBOHYDRATES MITABOUSM DISORDERS,
DIABETIC NEPHROPATHIES
POIHI 06314 i; 00b.' Iiiimunologic inochaiiisms In
cttdlovisculai disease Immunologic lend vasculic
diseise Ihumeo. animals)
ROIHL 17364 04 Big lenin' Biochemical and cllnicti
studies (human)
ROIHL 20381 03 Long leim study ol diabetic vasculaf
disease (human)
** ROIHL 2?581 02 NeurocirculatoiY contiol in diabetes
mellilus (human)
CARBOHYDRATES METABOLISM DISORDERS,
DIABETIC NEUROPATHIES
ROim ?0.'06 0? Carbohydiatps nucleotides and adienergic
inleiaclions (labbils. cats, lats)
•* ROlHl 2040003 Diabetic neuropathy and penpheial
wasculai diseases (human, hamsters)
ROIHL 20439 02 Etlects ol insulin on neurovasculai
transmission (human, rats, labbits. hamsters)
ROIHL 20446 02 Autonomic neuropathy in diabetic mice
(also lats)
CARBOHYDRATES METABOLISM DISORDERS,
DIABETIC RETINOPATHY
POIHL 06314 17 0064 Immunologic mechanisms in
caidiovascular disease Diabetic vascular disease (human,
rats, mice)
ROIHL 1363208 Vascular changes in diabetes mellitus
(human)
P50HL 14236-05 0009 Prevention of premature
arteriosclerosis ■ Clinical studies on,cholesterol metabolism
(human)
ROlHL-20455-03 Role of systemic hypertension on diabetic
retinopathy (human)
ROIHL 2208802 Metabolic basis tor diabetic
microangiopathy (cattle)
CARBOHYDRATES STRUCTURE
R01HL02942-22 Biochemistry of cardiovascular connective
tissue (human, cattle, primates)
ROlHL-0622117 Composition and structure of plasma
lipoproteins (human, turkeys, baboons)
P01HL09011-15 0005 A research and resource program
in blood - Characterization of hepatitis B antigen and the
cause of serum hepatitis (human)
" POlHL-1 1310-12 0099 Mechanisms of cardiovascular
disease Carbohydrate chemistry of thy-1 and related
synaptosomal proteins
P01HL-1I310-12 0103 Mechanisms of cardiovascular
disease - Heparin-Metabolism and function
" P01HL-11310-12 0105 Mechanisms of cardiovascular
disease - Biosynthesis of mammalian glycoproteins
(rabbits)
P50HL- 15389-07 0014 Pulmonaiy SCOR-Hypersensitivity
pneumonitis - Fractionation and characterization of pigeon
antigens
ROlHL-1547406 Structure and function of the
antihemophilic factor (human, cattle)
ROlHL-16166-05 Structure of alpha-l-antitrypsin in
relation to emphysema (human)
R01HL-17194-03 Comparison of two inherited forms of
alpha-I-antitrypsin (human)
" R01HL-17783-04 Complex carbohydrates -Structure,
function, synthesis (swine)
R01HL-17995-04 Cellular synthesis and release of
mucopolysaccharides (rabbits)
ROlHL-18714-04 Cardiovascular matrix -Morphogenesis
and maturation (human, chick embryo, mammal)
ROlHL-19011-03 Smooth muscle cell membrane
glycoprotein biosynthesis (cattle)
P50HL-19190-02 0005 Pulmonary SCOR-Pafhophysiology,
management of IRDS - Glycoproteins in mucous secretions
(human, cattle)
ROIHL 1982002 The chemistry and biological effects of
heparin (Rhesus, human, other mammals)
ROlHL-20500-02 Diabetic human brain microvascular
basement membrane (human)
ROlHL-20547 02 Glycoproteins in pulmonary alveolar
proteinosis (human)
ROlHL-20868-02 Regulation of glycoprotein biosynthesis in
lung (swine)
ROIHL-21615-01 Structural studies of lung heparinoid
polysaccharides (cattle)
ROlHL-21692-02 Purification of erythropoietin (human)
ROlHL-21763-09 Heparin and heparan sulfate- Structure
and activity (beef, hog)
ROlHL-22983-01 Studies on the catabolism of plasma
lipoproteins (rats)
CARBOHYDRATES STRUCTURE, SUGAR
SEQUENCE
ROlHL-15125-07 Molecular pathology of genetic disorders
in man
P50HL-1 5389-07 0015 Pulmonary SCOR-Hypersensitivity
pneumonitis - Fractionation and characterization of
thermophilic Actinomycetc antigens
R01HL17783-04 Complex carbohydrates-Structure.
function, synthesis (swine)
ROlHL-19084-03 Structure and function of serum
lipoproteins (human)
ROlHL-21480-01 Structure, source and functions of
alveolar glycoproteins (human, rabbits)
• I
ROIHI 21612 02 Biochemlitry o( lunf proteo|lycini
(human, rabbits)
RO 1 HI 2 1 6 1 5 0 1 Structural studies ol lung heparinoid
polysaccharides (cattle)
ROIHL 2161/02 Biochemistry ol lung proteoglycans
(rabbits, cattle)
ROIHL 21686 02 Purification of erylhiopoielin (human)
CARBOHYDRATES TRANSPORT (GENERAL)
PDIHI 06:'8!) 18 0132 Caidiovascular lespiialoiy
physiology and biochemistry Umbilical placental
circulatory responses (lambs)
ROIHL 15013 07 Lung oxidative metabolism and energy
production (rodents, rabbits)
POIHL 16851 04 0006 Human red cell membrane in
health and disease Hcxose transport and erythrocyte
membrane proteins (human)
POIHL 19737 02 0001 Cellular and molecular aspects ol
respiratory physiology Fatty acid metabolism in type II
alveolar cells (rats)
R23HL 21842 01 Control of sugar entry in normal and
diabetic heart (rats)
CARBOHYDRATES TRANSPORT, GLUCOSE
TRANSPORT
ROIHL 02835 21 Renal transport carrier for organic
compounds (dogs, rats)
■• P01HL08899 14 0054 Tolerance to respiratory gases m
health and disease Glucose transport across choroid
plexus (dogs)
ROIHL 12879 09 0005 Pulmonary transport and
metabolism in vivo Glucose transport by pulmonary
endothelium and epithelium (dogs)
ROIHL 13029-09 Metabolic regulation of sugar transport
(pigeons, rats)
** R01HL-M483 08 Energy conservation in heart
mitochondria (cattle, E coli, human)
R01HL-166I1-04 Digitalis-receptor of the heart (guinea
pigs, rats)
** POlHL-1685104 0006 Human red cell membrane in
health and disease - Hexose transport and erythrocyte
membrane proteins (human)
ROlHL-19463-02 Pathophysiology of acute renal failure
(rats)
ROlHL-20605-02 Microvascular responses during intestinal
absorption (rats)
ROlHL-221 72-01 Hypotension, renal ischemia and effect of
mannitol (dogs, rats)
ROlHL-22951-01 Studies on the affect of vitamin E on
platelets (human, rats)
CARBON
SEE ALSO RADIOISOTOPES. CARBON
P01HL-06314-17 0048 Immunologic mechanisms in
cardiovascular disease - Pathogenesis of glomerulonephritis
(rats, mice)
NOlHV-32919-12 Material development and testing
heparinization processes
N01HV-42928-07 Continued development of carbon film
deposits for prosthetics
CARBON 1 1
SEE RADIOISOTOPES. CARBON
CARBON 1 3 LABELED
SEE ISOTOPE LABELED. STABLE CARBON
CARBON-CARBON LIGASES
ROlHL-16628-05 Regulation of lipid metabolism (rats)
CARBON-CARBON LIGASES, ACETYl-COA
CARBOXYLASE
R01HL12399-13 Specific fatty acids and cholesterol
metabolism (gerbils, rats)
ROlHL-16364-04 Regulation of lipid biosynthesis and
transport (rats, swine, Xenopus)
ROIHL-16628-05 Regulation of lipid metabolism (rats)
ROlHL-18938-03 Pulmonary fatty acid and phospholipid
metabolism (rats)
ROlHL-204 11-03 Platelet fatty acid metabolism in
diabetes (rat, rabbit, guinea pig)
CARBON-CARBON LIGASES, PROPIONYL COA
CARBOXYLASE (ATP-HYDROLYZING)
ROlHL-16628-05 Regulation of lipid metabolism (rats)
CARBON DIOXIDE
SEE RESPIRATORY GASES, CARBON DIOXIDE
CARBON DIOXIDE TENSION
SEE RESPIRATORY GAS LEVELS, CARBON DIOXIDE TENSION
CARBON DIOXIDE TRANSPORT
SEE RESPIRATORY GAS TRANSPORT, CARBON DIOXIDE
TRANSPORT
CARBON MONOXIDE
R01HL-05556-19 Proteins, lipoproteins-Structure and
reactivity (chicken, human, diving mammals)
ROlHL-121 74-11 Ventilation/perfusion distribution in the
lung (human, mammals)
ROlHL-12524-10 Reaction of hemoglobin with ligands and
antibodies (human, carp)
ROlHL-131 57-09 Molecular oxygen carriers-Synthesis,
structure, bonding
CAR
ROIHI I35RI II Reacliont ol oiygan with h«m« protgmt
ROIHI 14 1 31 III Abnormal hemoglobin syndromes
(human)
ROIHI 15520 06 Total blood replaroment by lluorocaiboni
and polyols (rats)
ROIHI 15980 06 Reictions ol hemeproleint and oiyitn
(cetlle)
ROIHt 1668604 Properties ol cytochrome oxidase (cattle.
bacteria)
ROIHI 1/51703 Arterial wall oxygen trinsporl in
atherosclerosis (rabbits, dogs)
ROIHL 18969 02 Arterial wall oxygenation (rabbits, dogs)
ROIHL 19299 03 Myoglobin and oxygen supply to heart
and muscle cells (rats, pigeons)
P50HL 1936? 02 0006 A/S SCOR Atherosclerosis in
nonhuman primates Effects of cigarette smoking on
atherosclerosis (baboon)
ROIHL 1948803 Picosecond laser studies of heme
proteins
•• POIHL 1973702 0009 Cellular and molecular aspects ol
respiratory physiology Regulation of tissue oxygen tension
and body carbon monoxide stores (human, dogs)
POIHL 19/3/ 02 001 1 Cellular and molecular aspects of
respiratory physiology Chemical and metabolic factors on
peripheral chemoreceplor activity (cats)
ROIHL 19/4603 Proliferation and differentiation of
alveolar macrophages (mice, hamsters)
ROIHL 201/602 Biochemistry and genetics of salt
hypertension (rats)
ROIHL 20996-02 Structural and reactivity of iron and
cobalt complexes
ROlHL-22859 01 Effect of carbon monoxide on the
developing heart (rats)
CARBON MONOXIDE POISONING
SEE TOXICOLOGY. GAS POISONING. CARBON MONOXIDE
CARBON RADIOISOTOPES (11,14)
SEE RADIOISOTOPES. CARBON
CARBON-SULFUR LYASES, GLYOXALASE I
R01HL-2363I 01 Immunogenetic factors in allergic
respiratory diseases (human)
CARBONATES
ROlHL-20725-02 Mechanisms and cellular functions of ion
transport
CARBONATES, BICARBONATES
SEE ALSO SODIUM BICARBONATE
ROlHL-00759 29 Regulation of electrolyte and acid base
equilibrium (dogs)
POlHL-06285-18 0198 Cardiovascular respiratory
physiology and biochemistry - Renal tubular secretion of
hydrogen ion (animals)
POlHL-06285-18 0199 Cardiovascular-respiratory
physiology and biochemistry - Renal tubular reabsorption of
sodium chloride (hamsters, rabbits)
POlHL-07896-15 0029 Environmental biomedical research
program - Oxygen-helium diving resulting in high pressure
nervous syndrome (human, animals)
P50HL-14218-07 0018 Pulmonary SCOR-Newborn lung
center - Whole body buffering in acute hypercapnia (dogs)
POIHL-14388-07 0191 Regulation of the circulation in
pathological states Regulation of chloride transport in
epithelial membranes (turtles)
ROlHL-16135-05 Mechanisms of cardiac autorhythmicity
(dogs, bats)
ROIHL 17963-04 Human erythrocyte carbonic anhydrase
ROlHL-1835103 Brain metabolism, acid-base balance.
and respiration
ROlHL-18606 04 Pathogenesis and measurement of
pulmonary edema (human, rabbits, dogs)
ROlHL-19008-02 Carbon dioxide diffusion in lung and
muscle tissues (dogs)
R23HL-19601-01 Cardiac response to chronic metabolic
acidosis (rats)
POlHL-19737-02 0004 Cellular and molecular aspects of
respiratory physiology - Rapid reactions and erythrocyte
exchanges of blood during respiratory transport
CARBONIC ANHYDRASE
SEE DEHYDRATASES. CARBONIC ANHYDRASE
CARBONIC ANHYDRASE INHIBITORS
SEE ENZYME INHIBITORS. CARBONIC ANHYDRASE INHIBITORS
CARBONYL COMPOUNDS
ROlHL-18163-04 Red cell membrane effects due to
oxidizing agents
CARBOPOLYCYCLICS
SEE CYCLICS. CARBOPOLYCYCLICS
CARBORANES
SEE METALS. BORON COMPOUNDS. BORANES
CARBOXYL GROUPS
ROlHL-14680-07 Specific enrichment of myoglobins for
carbon 13 NMR (catacea)
ROlHL-16471-05 Cardioactive alloyohimbines and related
indole alkaloids
ROlHL-17930-03 Platelet membrane function -Assessment
and application (animals)
ROlHL-19278-03 Ristocetin induced platelet aggregation
(human)
•Excludes routine methodokjgy OR covers only general projects which preclude indexing
Oneirted significantly to above subject
at the specific level.
M Grant has subproiects describing specific research aspects.
See Appendix for mvestigator's name and grant number.
(contd)
CAR
ROlHL-20079-02 0001 Thromboresistant material ■ Active
and passive thromboresistant surfaces
ROlHL-20764-02 Elaslin and calcification in pulmonary
and vascular disease (human, mammals)
CARBOXYL GROUPS, CARBOXYLATION
♦* POlHL-1141411 0035 Thrombosis and atherosclerosis
program • Mechanism of action of vitamin K (rats)
ROlHL-14847-07 Mechanism of action of vitamin K and
anticoagulants (rats)
•* ROlHL-20161-02 Role of gamma-carboxyglutamic acid in
blood coagulation (human, cattle)
ROlHL-20577-03 The mechanism of action of vitamin K
ROlHL-21543-02 Structure-function relation of blood
clotting proteins (rabbits)
CARBOXYLATION
SEE CARBOXYL GROUPS, CARBOXYLATION
CARBOXYLESTERASES
SEE CARBOXYLIC ESTER HYDROLASES, CARBOXYLESTERASE
CARBOXYUC ACIDS, ENOIATES
ROlHL-21367-02 Polyether ionophores-Synthesis of X537A
and analogs
CARBOXYLIC ESTER HYDROLASES, ARGININE
ESTERASE
P50HL14153-07 0015 Johns Hopkins Lung Center-
Chronic diseases of airways - Kinins and human lung
P60HL-1516007 0016 Center for sickle cell disease -
Kinin and plasm in system in sickle cell disease (human)
ROlHL-18526-03 Kinins and the human lung
P50HL-19157-02 0008 Studies in cystic fibrosis and
bronchiolitis - Serum proteins in cystic fibrosis (human)
CARBOXYUC ESTER HYDROLASES,
CARBOXYLESTERASE
ROlHL-04457-20 Cellular aspects of active transport (fish,
rabbits, anurans, turtles)
CARBOXYPEPTIDASE
SEE PROTEASES AND PEPTIDASES, CARBOXYPEPTIDASE
CARBOXYPEPTIDASE A
SEE PROTEASES AND PEPTIDASES, CARBOXYPEPTIDASE
CARBOXYPEPTIDASE B
SEE PROTEASES AND PEPTIDASES, CARBOXYPEPTIDASE
CARCINOGENESIS, CHEMICAL
SEE NEOPLASTIC TRANSFORMATION, CARCINOGENESIS,
CHEMICAL
CARCINOGENS (GENERAL)
SEE NEOPLASTIC TRANSFORMATION, CARCINOGENS
(GENERAL)
CARCINOGENS, CHEMICAL
SEE NEOPLASTIC TRANSFORMATION, CARCINOGENS,
CHEMICAL
CARCINOGENS, DRUGS
SEE NEOPUSTIC TRANSFORMATION, CARCINOGENS,
CHEMICAL
CARCINOID
SEE NEOPLASMS OF NERVOUS SYSTEM, CARCINOID
CARDENOUDES
SEE CARDIAC GLYCOSIDES AGLYCONES. CARDENOLIDES
CARDIAC ANEURYSMS
SEE HEART DISORDERS, ANEURYSMS
CARDIAC ARRHYTHMIA
SEE HEART DISORDERS, ARRHYTHMIA
CARDIAC ASSIST
SEE CAROIOVASCUUR SURGERY, CIRCUUTORY ASSIST
CARDIAC GLYCOSIDES
SEE ALSO STEROIDS GLYCOSIDES
ROlHL-02953-17 Autonomic and cardiovascular
pharmacology (rats, rabbits, dogs, guinea pigs)
•* ROlHL-05883-18 0003 Reflex control of resistance and
capacitance vessels - Cardiac glycosides and sympathetic
nerve terminals in vascular smooth muscle
•* ROlHL-05883-18 0004 Reflex control of resistance and
capacitance vessels - Left ventricular receptors with
nonmedullated vagal afferents (cats)
ROlHL-08893-14 Structure and function of membrane
proteins (human)
POlHL-10436-13 0014 A multidisciplinary study of
congenital heart disease - Cardiovascular pharmacology
(dog) ^ , ,
POIHLI 1351-12 0001 Cellular and molecular
mechanisms of myocardial function - Ionic control of
myocardial contractility (animals)
POlHL-l 1351-12 0010 Cellular and molecular
mechanisms of myocardial function - Basic ionic exchange
studies (rats)
POlHL-13108-09 0017 Clinical heart transplantation -
Electrophysiology of the transplanted denervated human
h«irt , , ..
•* P01HL13108-09 0018 Clinical heart transplantation •
Etoctrophyjiologic studies of cardiac drugs in the
demrvited hurt
82
ROlHL-13339-08 Pharmacology of developing cardiac
tissues (chick embryo)
R01HL-13427-09 Neural control of blood volume (monkeys,
dogs)
POlHL-14388-07 0220 Regulation of the circulation in
pathological states - Pharmacology of the coronary
circulation in man
* POlHL-15194-07 0004 Pathophysiology of
cardiopulmonary dysfunction - Specialized electrophysiology
fibers-Electrogenic basis of glycosides (mammals)
ROlHL-15416-06 Cardiovascular control in normal and
disease states (dogs, baboons)
* ROIHL 16052-05 Cardiac glycosides-Mechanism of
inotropic action (dogs)
POlHL-161 17-05 0005 Ion movements and membranes in
cardiovascular control - Properties of isolated cell
membranes (rabbits, cats)
ROlHL-16549-04 Cardiotonic steroid-NaK ATPase
interactions (cattle)
R01HL167 10-03 Myocardial subcellular localization of
calcium (dogs)
** P60HL-1726904 0017 National heart and blood vessel
research and demonstration center - Cell membrane (dogs,
rabbits)
P60HL-17269-04 0022 National heart and blood vessel
research and demonstration center - Medicinal chemistry
(rabbit, dog, guinea pig)
ROlHL-17629-03 Developmental aspects of cardiovascular
function (human, cats, rabbits)
** ROIHL- 181 85-04 Cardiac glycosides and diuretics-Role of
NaO pump (dogs)
ROlHL-18308-03 Comprehensive studies of mucociliary
transport (dogs)
ROlHL-187 11-03 Electrophysiology of heart cells (rats,
chicks)
ROlHL-19076-03 Vagal control of heart tale-A biophysical
model (rabbits)
** ROlHL-191 29-04 Cardiac glycosides-Mechanisms of
cellular actions
** POIHL- 192 59-03 0004 Digoxin-specific antibody in human
therapy - Digitalis-specific antibodies pharmacological
studies (human, dogs, sheep)
ROlHL-20230-02 Analysis of the action potential of
cardiac muscle (sheep)
** ROlHL-20262-02 Cardiac glycosides and the mechanism
of the sodium-potassium pump
POlHL-20552-02 0004 The development and regression of
cardiac hypertrophy - Ventricular function in experimentally
induced hypertrophy (hogs, sheep, baboons)
** ROlHL-20558-02 Cardiac electrophysiology-Effects of ions
and drugs
** ROlHL-210 14-01 Mechanism of the inotropic action of
cardiac glycosides
ROlHL-21158-02 Cardiac receptors with vagal C-fiber
afferents (cats)
R23HL-21262-02 Sodium-calcium interactions in
mammalian myocardium (rabbits, cats)
ROlHL-21996-01 Alteration of digitalis and aldosterone
disposition (rats, rabbits, mice, dogs)
ROlHL-22039-02 Ion transport in cardiac muscle (dogs,
rodents, cattle)
** ROlHL-22079-01 Heart receptor sites for digitalis and
steroid hormones (animals)
ROlHL-22484-01 Neural control of cardiac conduction and
excitation (dogs)
ROlHL-22568-01 pH effect in heart cells-Influence of
cardiac drugs (tissue culture, rats)
ROlHL-22594-01 Reflex control of the circulation in heart
failure (dogs)
M POlHL-226 19-01 Cellular mechanisms of heart failure
** POlHL-226 19-01 0002 Cellular mechanisms of heart
failure - Structure of sodium, potassium-adenosine
triphosphatase (lambs, dogs)
" POlHL-226 19-01 0004 Cellular mechanisms of heart
failure - Mechanism of action of Na, K-ATPase (sheep,
cattle)
POlHL-226 19-01 0008 Cellular mechanisms of heart
failure - Molecular mechanisms and differential contractile
responsiveness in VSM (dogs)
POlHL-226 19-01 0009 Cellular mechanisms of heart
failure - Sarcoplasmic reticulum in cardiac, skeletal and
smooth muscle (rabbits, dogs)
CARDIAC GLYCOSIDES, DIGITALIS
POlHL-06312-17 0030 Surgical cardiology - Total
artificial heart (calves)
POlHL-063 12-17 0051 Surgical cardiology - Diuretic
therapy on myocardial electrolyte composition and water
content (human)
ROlHL-07776-15 Sudden death and cardiac arrhythmias
(human, dogs, cats)
ROlHL-08508-15 Cardiac conductivity and automaticity
(human, dogs, rabbits)
ROlHL-10608-12 Digoxin-specific antibodies (human)
ROlHL-10951-11 Neural control of the heart (dogs, rats)
POlHL-12738-10 0035 Physiologic pharmacology and its
clinical applications - function and dysfunction of the
sinoatrial node (human)
POlHL-12738-10 0076 Physiologic pharmacology and its
clinical applications - Pediatric cardiac electrophysiology
and pharmacology (human, dogs)
CAR
POlHL-12738-10 0108 Physiologic pharmacology and its
clinical applications - Developmental electrophysiology and
pharmacology (human, animals)
ROlHL-12774-08 Ionic coupling in activation of cardiac
muscle (frogs, guinea pigs)
POlHL-13108-09 0008 Clinical heart transplantation -
Physiology and pharmacology of the transplanted human
heart
POlHL-13108-09 0017 Clinical heart transplantation -
Electrophysiology of the transplanted denervated human
heart
ROlHL-13306-08 Pharmacological control of cardiac
membrane currents (cattle, rabbits)
ROlHL-13666-06 Pharmacology of genesis of cardiac
rhythmicity (rats, cats)
ROlHL-13870-09 Control of myocardial sarcotubular
calcium stores (dogs)
P50HL-14187-07 0005 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses - Pulmonary
hypertension and cardiac function (dogs, human)
POlHL-14388-07 0211 Regulation of the circulation in
pathological states - Choline acetyltransferase activity
(rats)
* POlHL-14388-07 0234 Regulation of the circulation in
pathological states - Effects of antiarrhythmic drugs on the
autonomic system (dogs)
ROIHL- 14545-06 Mechanics of compensatory ventricular
hypertrophy (dogs)
ROIHL 14646-05 Pathophysiology of myocardial ischemia
(dogs, rats)
POlHL-15194-07 <1004 Pathophysiology of
cardiopulmonary dysfunction - Specialized electrophysiology
fibers-Electrogenic basis of glycosides (mammals)
ROlHL-15522-06 Influence of mannitol on ischemia
cardiac muscle (dogs, cats, rats)
ROlHL-15758-06 Catecholamine release in the heart
(dogs)
ROIHL- 15985-06 Metabolic and hormonal control of
cardiac contraction
ROlHL-16076-06 Electrophysiology of fibrillation and
defibrillation (human)
ROlHL-16135-05 Mechanisms of cardiac autorhythmicity
(dogs, bats)
POlHL-16607-05 0003 Calcium ion and control of
cardiovascular function - Calcium transport in
sarcoplasmic membranes (animals)
** ROlHL-16611-04 Digitalis-receptor of the heart (guinea
pigs, rats)
ROlHL-16656-06 Left ventricular function in exercise
(dogs)
P60HL-17269-04 0017 National heart and blood vessel
research and demonstration center - Cell membrane (dogs,
rabbits)
** ROlHL-17451-05 Digitalis effects on cardiac automaticity
mechanisms
ROlHL-17452-04 Depolarization induced cardiac
automaticity (human, animals)
** ROlHL-17555-05 Distribution and metabolism of labeled
digitaloids (dogs, guinea pigs)
** ROlHL-17796-04 Importance of aminosugars in digitalis
activity (cats, rabbits)
** ROlHL-17993-04 0007 Ventricular dynamics from
surgically inserted markers - Digitalis after coronary artery
surgery (human)
** ROlHL-18003-05 Digitalis-Mechanism and reversal studies
(dog, sheep, duck, guinea pig, human)
** ROlHL-18598-03 Role of Na, K-ATPase inhibition on
digitalis action
** ROlHL-18657-03 Pharmacologic studies on neurogenic
digitalis effects (human, cats, dogs)
ROlHL-18796-04 Experimental cardiac arrhythmias (dogs)
ROlHL-19045-03 Electrophysiology of cardiac automaticity
(human, dogs)
** POlHL-19259-03 0004 Digoxin-specific antibody in human
therapy - Digitalis-specific antibodies pharmacological
studies (human, dogs, sheep)
** ROlHL-19487-03 Cardiac actions of digitalis (dogs, cats)
ROlHL-20190-02 Pathogenesis of cardiac hypertrophy
(dogs)
" ROlHL-21052-01 Evaluation of a digitalis therapy advisor
ROlHL-2 11 58-02 Cardiac receptors with vagal C-fiber
afferents (cats)
** R23HL-21196-02 Digitalis induced arrhythmia and NAO KO-
atpase activity (dogs)
ROlHL-21922-01 Transient currents induced by
strophanthidin in the heart
** ROlHL-21996-01 Alteration of digitalis and aldosterone
disposition (rats, rabbits, mice, dogs)
ROIHL 22039-02 Ion transport in cardiac muscle (dogs,
rodents, cattle)
** ROlHL-22079-01 Heart receptor sites for digitalis and
steroid hormones (animals)
** POlHL-22619-01 0003 Cellular mechanisms of heart
failure - Digitalis induced inotropy in myocardial ischemia
heart failure (animals)
POlHL-22619-01 0010 Cellular mechanisms of heart
failure - Mitochondria in heart and smooth muscle (rabbits,
rats, dogs)
ROlHL-22977-01 Role of vasoconstrictor mechanisms in
heart failure (human, dogs)
(contd)
txkitn mutine nwHiodoloiy OR awn only general projwAs which preclude
' • yi»:iteJ sif ; Jficinthf to above subject.
indexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
CAR
CARDIAC OLYCOSIDES, DIOITOXIN
ROIMI 13639 07 ficlou sllonng the coins* ol myoc«idial
dysfunction (cats)
ROIHl 1366606 Phaimacoloiy ol genesis ol caidiac
ihythmicity (fits, cats)
M POIHL 19259 03 Digoiin specilic antilwdy in human
therapy
R23HI 21083 02 Phatmacokinetics ol digoxin and digitoiin
In humans (lats)
ROIHI 2199601 Aitacatlon ol digitalis and aldostatone
disposition (rats, rabbits, mice, dogs)
CARDIAC OlYCOSIDES, DIGOXIN
POIHI 10436 13 0002 A multidisciplinai> study o(
congenital heart disease Myocardial perlormance.
metabolism and ultrastructure (human, cats, rats)
ROIHL 10608 12 Olgoxin specific antibodies (human)
•• POIHI 11310 12 0059 Mechanisms ol cardiovascular
disease Contractility Acute response to diogoxin after
heart surgery (children)
POIHL 12738 10 003S Physiologic pharmacology and its
clinical applications Function and dysfunction of the
sinoatrial node (human)
POIHL 1310809 0008 Clinical heart transplantation ■
Physiology and pharmacology of the transplanted human
heart
POIHL 1310809 0018 Chnical heart transplantation
Electrophysiologic studies of cardiac drugs in the
denervated heart
ROIHL 1366606 Pharmacology ol genesis of cardiac
rhythmiclty (rats, cats)
POIHL 1438807 0220 Regulation of the circulation in
pathological states Pharmacology of the coronary
circulation in man
POIHL 14388-07 0234
pathological states
Regulation of the circulation in
Effects of antiarrhythmic drugs on the
autonomic system (dogs)
ROIHL 17631-05 Experimental congestive heart lailure and
hypertrophy (cats)
ROIHLI 7796-04 Importance of aminosugars in digitalis
activity (cats, rabbits)
ROIHL 1785303 Peripheral circulation in heart failure
(animals)
M POlHL-19259-03 Digoxin-specific antibody in human
therapy
** POlHL-1925903 0001 Digoxin-specific antibody in human
therapy - Primary structure of monoclonal antibodies
(rabbits)
** POlHL-19259-03 0002 Digoxin-specific antibody in human
therapy ■ Chemical semi-synthesis of digoxin-specific
antibody (rabbits)
** P01HL19259-03 0003 Oigoxin-specific antibody in human
therapy - Synthesis of dogoxinspecific antibody in
continuous cell culture (human, sheep)
POlHL-19259-03 0006 Digoxin-specific antibody in human
therapy - Core
R23HL-21083-02 Pharmacokinetics of digoxin and digitoxin
in humans (rats)
ROlHL-21996-01 Alteration of digitalis and aldosterone
disposition (rats, rabbits, mice, dogs)
R23HL-2230901 Cardiovascular pharmacodynamics in
immature dogs
R23HL-22575-01 Factors modifying cardiac digoxin effects
and content (dogs, cats)
ROlHL-22750-01 Digoxin in heart failure with sinus
rhythm (human)
ROlHL-23980-01 Effects of digoxin therapy in newborn
and adult sheep
CARDIAC GLYCOSIDES, OUABAIN
ROlHL-02953-17 Autonomic and cardiovascular
pharmacology (rats, rabbits, dogs, guinea pigs)
P01HL0628518 0199 Cardiovascular-respiratory
physiology and biochemistry ■ Renal tubular reabsorption of
sodium chloride (hamsters, rabbits)
POlHL-06664-17 0039 Cardiopulmonary function In
remediable vascular disease ■ Transepithelial active
transport and cell volume regulation (frogs)
P01HL10436-13 0014 A multidisciplinaiy study of
congenital heart disease Cardiovascular pharmacology
(dog)
R01HL10897-12 Effects of hormones on cardiac
electrogenesis (rabbits, guinea pigs, dogs)
POlHL-12157 11 0033 Functions and mechanisms of cell
membrane ion transport Immunology aspects of active
Na-K transport in sheep red cell (also human, mice)
P01HL-12157-U 0049 Functions and mechanisms of cell
membrane ion transport - Ouabain-insensitive cation
transport in duck red cells
P01HL1215711 0052 Functions and mechanisms of cell
membrane Ion transport - Active electrical properties of the
synthetic strand
POlHL-12738-10 0076 Physiologic pharmacology and its
clinical applications ■ Pediatric cardiac electrophysiology
and pharmacology (human, dogs)
POIHL-12738-10 0108 Physiologic pharmacology and its
clinical applications - Developmental electrophysiology and
pharmacology (human, animals)
ROlHL-13666-06 Pharmacology of genesis of cardiac
rhythmiclty (rats, cats)
ROIHL- 138 70-09 Control of myocardial sarcotubular
calcium stores (dogs)
83
POIHI 14414 07 0016 Invironmentil Influences on
cardiorespiratory and cellular lunclionj flloctj ol
piBSJure on membrane and celluliir tunclion (human,
rabbits)
ROIHI 14545 06 Mechanics ol compensatory ventricular
hypurtrophy (dogs)
POIHI 14985 0/ QUI 2 Adaptation to hypoxia Direct
effect ol hypoxia on pulmonary vascular smooth muscle
(rats, dogs)
POIHL 15194 07 0004 Pathophysiology ol
cardiopulmonaiy dysfunction Specialiied electrophysiology
fibers Eleclrogenic basis ol glycosides (mammals)
ROIHL 15231 05 Mechanisms ol hemodynamic changes
during digestion (dogs)
ROIHL 1575806 Catecholamine release in the heart
(dogs)
POIHL 1583506 0018 Study of muscles related to heart
disease Pharmacology of excitation coupling in muscle
(frog, barnacles)
ROIHL 16318 21 Biochemistry and pharmacology of Na K
transport
P60HL 17269 04 0017 National heart and blood vessel
research and demonstration center Cell membrane (dogs,
rabbits)
ROIHL 1779604 Importance of aminosugars in digitalis
activity (cats, rabbits)
** ROIHL 17879 04 Molecular structure of the ouabain
sensitive ATPase (dogs)
ROIHL 18053-03 Intracellular ronic activities in heart
muscle (frogs)
ROIHL 1859803 Role of Na. K-ATPase inhibition on
digitalis action
ROIHL 18599-02 Cardiovascular pharmacology of
ionophores (dogs)
ROIHL 19045 03 Electrophysiology of cardiac automaticity
(human, dogs)
ROIHL 19129-04 Cardiac glycosides-Mechanisms of
cellular actions
R01HL19995-02 Sensory transduction in cardiac
mechanoreceptors (cats, frogs, rats)
ROlHL-2026202 Cardiac glycosides and the mechanism
of the sodium-potassium pump
ROlHL-21371-02 Energy loss microanalysis of myocardial
cations
ROlHL-21525-02 Effect of cations, anions and water upon
blood vessels (dogs, rats)
ROlHL-22039-02 Ion transport in cardiac muscle (dogs.
rodents, cattle)
ROlHL-22558 01 pH effect in heart cells-Influence of
cardiac drugs (tissue culture, rats)
CARDIAC GLYCOSIDES AGLYCONES,
BUFADIENOLIDES
ROlHL-181 18-04 Total synthesis of cardiac aglycones
CARDIAC GLYCOSIDES AGLYCONES,
CARDENOLIDES
SEE ALSO CARDIAC GLYCOSIDES AGLYCONES, DIGITOXIGENIN
SEE ALSO CARDIAC GLYCOSIDES AGLYCONES, DIGOXIGENIN
SEE ALSO CARDIAC GLYCOSIDES AGLYCONES.
STROPHANTHIDIN
ROlHL-181 18-04 Total synthesis of cardiac aglycones
ROlHL-21457-01 C(17)-side group geometry and
cardenolide activity (cats, guinea pigs)
CARDIAC GLYCOSIDES AGLYCONES,
DIGITOXIGENIN
ROlHL-181 18-04 Total synthesis of cardiac aglycones
CARDIAC GLYCOSIDES AGLYCONES,
DIGOXIGENIN
R01HL-16549-04 Cardiotonic steroid-NaK ATPase
interactions (cattle)
CARDIAC GLYCOSIDES AGLYCONES,
STROPHANTHIDIN
ROlHL-05883-18 0003 Reflex control of resistance and
capacitance vessels - Cardiac glycosides and sympathetic
nerve terminals in vascular smooth muscle
ROlHL-09914-13 The myocardium in diabetes mellitus
(dogs, monkeys)
POlHL-1 1351-12 0001 Cellular and molecular
mechanisms of myocardial function ■ Ionic control of
myocardial contractility (animals)
ROlHL-13639-07 Factors altering the course of myocardial
dysfunction (cats)
ROlHL-13666-06 Pharmacology of genesis of cardiac
rhythmiclty (rats, cats)
ROlHL-146 14-07 Voltage control of contraction in heart
(sheep)
R01HL14899-07 Mechanism and prevention of cardiac
arrhythmias (dogs)
R01HL-I6052-05 Cardiac glycosides-Mechanism of
inotropic action (dogs)
R01HL161 52-06 Electrophysiology of neonatal to adult
heart (cats, frogs, guinea pigs)
ROlHL-17451-05 Digitalis effects on cardiac automaticity
mechanisms
ROlHL-19487-03 Cardiac actions of digitalis (dogs, cats)
ROlHL-21922-01 Transient currents induced by
strophanthidin in the heart
CAR
CARDIAC MUSCLE
Ml HIAHI MYor.ARDIUM
CARDIAC OUTPUT
Sll HI AH I MJNCMON. (.AMiJIAf, Olirplir
CARDIAC OUTPUT ABNORMALITIES
Sfl HfAHI UI',(Jkl)( K', OIJIPUI AUNOWMAllTlfS
CARDIAC TAMPONADE
Sir HfARI OISORDIRS. CARDIAC lAMPONADF
CARDIODYNAMICS
S[[ HEART FUNCTION
CARDIOGENIC SHOCK
SEE HfARI DISORDERS, CARDIOGENIC SHOCK
CARDIOLIPINS
SEE PHOSPHOLIPIDS, PHOSPHOGIYCERIDES. CARDIOLIPINS
CARDIOMYOPATHIES
SEE HEART DISORDERS, MYOCARDIAL DISORDERS
CARDIOMYOPATHY, HYPERTROPHIC
SEE HEART DISORDERS. MYOCARDIAL DISORDERS,
HYPERTROPHIC MYOCARDIOPAIHY
CARDIPPROTECTIVE AGENTS
SEE CAROIOVASCUUR AGENTS, CARDIOTONIC AND
CARDIOPROTECTIVE DRUGS (GENERAL)
CARDIOPULMONARY BYPASS
SEE CARDIOVASCULAR SURGERY, CIRCULATORY ASSIST
HEART LUNG BYPASS
CARDIOPULMONARY DISEASE
SEE RESPIRATORY CIRCUUTORY DISORDERS. PULMONARY
HEART DISEASE
CARDIORENAL DISORDERS
SEE KIDNEY-CIRCULATORY DISORDERS
CARDIOTONIC DRUGS
SEE CARDIOVASCULAR AGENTS. CARDIOTONIC AND
CARDIOPROTECTIVE DRUGS (GENERAL)
CARDIOVASCULAR AGENTS
SEE ALSO CARDIOVASCULAR DISORDERS CHEMOTHERAPY
ROlHL-01486-23 Quantitative study of T-wave mechanisms
(human, rabbits, dogs, chickens)
ROlHL-03181-21 0025 Hemodynamics as applied to
surgical problems - Vascular stenosis (dogs)
" P01HL-06285-I8 0186 Cardiovascular-respiratory
physiology and biochemistry - Leukocyte hormone receptors
and cyclic nucleotides (tissue culture)
POlHL-06835-17 0039 Cardiovascular disease -
Reversibility of vascular changes in renal hypertension
(rats)
POlHL-06835-17 0051 Cardiovascular disease ■
Cardiopulmonary volume in hypertension (human)
ROlHL-10503-13 Cardiac ion transport and ultrastructure
(rats, guinea pigs, rabbits)
ROlHL-10582-12 Thrombosis and hemostasls-Analysis,
methods and standards (human, cattle, venom)
ROlHL-10608-12 Digoxin-specific antibodies (human)
M POlHL-12373 10 Cardiopulmonary physiology and
pathophysiology
POlHL-1237310 0005 Cardiopulmonary physiology and
pathophysiology - Characterization of fetal and neonatal
myocardium (human, cats)
ROlHL-13636-08 Effects of pharmacologic agents on heart
metabolism (human, rodents)
M POlHL-14388-07 Regulation of the circulation in
pathological states
POlHL-14414-07 0010 Environmental influences on
cardiorespiratory and cellular functions • Pressure effects
on cardiac electrical phenomena (animals)
R01HL15985-06 Metabolic and hormonal control of
cardiac contraction
ROlHL-16471-05 Cardioactive alloyohlmbines and related
indole alkaloids
R01HL-16474-05 Antibiotic-ion interactions (model
membranes)
POlHL-16607-05 0003 Calcium ion and control of
cardiovascular function • Calcium transport In
sarcoplasmic membranes (animals)
R01HL16643-02 Fluorocarbon emulsions as artificial
blood (animals)
P60HL-1 7269-04 0024 National heart and blood vessel
research and demonstration center - Section of
experimental cardiovascular surgery-Core facility
ROlHL-17341-03 Practical total synthesis of
prostaglandins
** ROIHL- 17993-04 0003 Ventricular dynamics from
surgically inserted markers - Effects of pharmacologic
agents on left ventricular dynamics (human)
ROlHL-18084-03
(calves)
ROlHL-18096-04
(primates, dogs)
ROIHL-1825303
ROlHL-18590-03
(dogs, monkeys)
ROlHL-19000-03
^&cludes routine methodotogy OR covers only general projects which preclude indexing
Oiieiited sitniflcantly to alwve subject.
at the specific level.
M Gram has subprojeds describing specific research aspects.
See Appendix for mvestigator's name and grant number.
Artificial heart and related problems
Vasoactive agents in splanchnic viscera
Structure of the palytoxins
Cerebral blood flow after cardiac arrest
Irreversible myocardial injury (rats)
(contd)
CAR
ROlHL-1937803 Relation o1 mitochondrial changes to
cardiac failure (dogs, rats)
ROlHL-19399-02 Atherosclerosis -Early events and
regression factors (rats)
ROlHL-2008002 Surgically induced myocardial edema
(dogs)
ROlHL-20190-02 Pathogenesis of cardiac hypertrophy
(dogs) . . u. ■
** ROlHL-22005-01 Intermittent retroperfusion of ischemic
myocardium (dogs)
** ROlHL-22269-01 Excitation-contraction coupling in
enlarged hearts (rabbits)
** ROlHL-22685-01 Drugs and excitation-contraction coupling
in heart (animals)
ROlHL-22718-01 Cardiovascular drug interactions-
Metabolism models (dogs)
ROlHL-22732-01 Central organization of cardiac afferent
nerves (cats, monkeys)
CARDIOVASCULAR AGENTS, ANTIARRHYTHMIC
AGENTS
ROlHL-04666-19 Artificially paced hearts-Technology,
physiology (human, dogs)
** ROlHL-05806-18 Analysis of antiarrhythmic agents (dogs,
rabbits)
POlHL-06285-18 0155 Cardiovascular-respiratory
physiology and biochemistry - Therapeutic alterations,
contractile state in heart failure
** POlHL-0630818 0011 Mechanisms and therapy of
circulatory disease Blood flovi and electrical dysfunction
in ventricular arrhythmia (human)
POlHL-06308-18 0025 Mechanisms and therapy of
circulatory disease - Subcellular calcium pools in the
genesis of arrhythmias (dogs)
** POlHL-06308-18 0029 Mechanisms and therapy of
circulatory disease ■ Characterization of the patient with
recurrent ventricular arrhythmias
POlHL-06308-18 0037 Mechanisms and therapy of
circulatory disease ■ Electrophysiology, blood flow, and ANS
in ventricular fibrillation (dogs)
ROlHL-0713917 Cardiodynamics and metabolism of
congestive failure (human, dogs)
** R01HL07776-15 Sudden death and cardiac arrhythmias
(human, dogs, cats)
** ROlHL-08508 15 Cardiac conductivity and automaticity
(human, dogs, rabbits)
POlHL-08682-15 0017 Regulation of the cardiovascular
system - Neurally induced cardiac dysrhythmias (dog)
R01HL09283-14 Pharmacology of molluscan hearts (also
rabbits)
P01HL1043613 0002 A multidisciplinary study of
congenital heart disease - Myocardial performance,
metabolism and ultrastructure (human, cats, rats)
** P01HL11310-12 0078 Mechanisms of cardiovascular
disease ■ Ventricular arrhythmias in acute myocardial
infarction (dogs)
P01HL-n310-12 0087 Mechanisms of cardiovascular
disease - Electrophysiology and electropharmacology of the
heart (dogs)
** POlHL-12738-10 0001 Physiologic pharmacology and its
clinical applications • Clinical pharmacology of cardioactive
drugs (human) .
** P01HL12738-10 0035 Physiologic pharmacology and its
clinical applications - Function and dysfunction of the
sinoatrial node (human)
** POlHL-12738-10 0042 Physiologic pharmacology and its
clinical applications - Centrogenic cardiac arrhythmias
(cats)
•* POlHL-1273810 0044 Physiologic pharmacology and its
clinical applications ■ Cardioactive drugs and
electrophysiological properties of cardiac cells (sheep)
POlHL-12738-10 0076 Physiologic pharmacology and its
clinical applications - Peniatric cardiac electrophysiology
and pharmacology (human, dogs)
POlHL-12738 10 0080 Physiologic pharmacology and its
clinical applications - Electrophysiology of cardiac muscle
in the mitral valve (monkeys)
POIHL 12738-10 0081 Physiologic pharmacology and its
clinical applications ■ Ultrastructural and electrophysiologic
alteration of myocardium (human, dogs)
POIHL 12738-10 0107 Physiologic pharmacology and its
clinical applications - Blood superfused cardiac fibers
(dogs) , . .
•* POIHL 12738-10 0108 Physiologic pharmacology and its
clinical applications • Developmental electrophysiology and
pharmacology (human, animals)
POlHL-1273810 0109 Physiologic pharmacology and its
clinical applications - Effects of calcium blockers on
skeletal and cardiac muscle (cats)
•* POlHL-12738 10 0110 Physiologic pharmacology and its
clinical applications Physiology and pharmacology of
arrhythmias (dogs)
POIHL 1273810 0117 Physiologic pharmacology and its
clinical applications Ventricular arrhythmias in ischemic
heart disease (human)
** P01HL12738-10 0132 Physiologic pharmacology and its
clinical applications • Coronary occlusions and arrhythmias
(dogs)
** POlHL-1273810 0136 Physiologic pharmacology and its
clinical applications -
POIHL 13108-09 0008 Clinical heart transplantation -
Physiology and pharmacology of the transplanted human
heart
•Excludes routine methodotogy OR covers only general projects which preclude
"Onented significantly to above subject.
84
POlHL-13108-09 0017 Clinical heart transplantation •
Electrophysiology of the transplanted denervated human
heart
P01HL13 10809 0018 Clinical heart transplantation -
Electrophysiologic studies of cardiac drugs in the
denervated heart
POlHL-13108-09 0019 Clinical heart transplantation -
Effect of autonomic nervous system on arrhythmias
(human)
ROlHL-13375-09 Cellular potential changes causing
cardiac arrhythmias (dogs)
ROlHL-1363608 Effects of pharmacologic agents on heart
metabolism (human, rodents)
' R01HL13666-06 Pharmacology of genesis of cardiac
rhythmicity (rats, cats)
' P01HL14388-07 0234 Regulation of the circulation in
pathological states - Effects of antiarrhythmic drugs on the
autonomic system (dogs)
P01HL144 14-07 0010 Environmental influences on
cardiorespiratory and cellular functions • Pressure effects
on cardiac electrical phenomena (animals)
ROlHL-146 14-07 Voltage control of contraction in heart
(sheep)
R01HL147 17-06 Hemodynamics and heart structure -
Ventricular overload (dogs)
* ROlHL-1483206 Myocardial cells-Autonomic and rhythmic
mechanisms (chick embryo, rats)
* ROlHL-14899-07 Mechanism and prevention of cardiac
arrhythmias (dogs)
* ROlHL-15190-07 Physiological basis of arrhythmias and
their therapy (human)
P01HL15194-07 0004 Pathophysiology of
cardiopulmonary dysfunction - Specialized electrophysiology
fibers-Electrogenic basis of glycosides (mammals)
ROlHL-15681-06 Coronary flow studies of partially
obstructed vessels (dogs)
ROlHL-1574006 In vitro studies on heart cell function
(rats)
R01HL16076-06 Electrophysiology of fibrillation and
defibrillation (human)
ROlHL-16135-05 Mechanisms of cardiac autorhythmicity
(dogs, bats)
ROlHL-17452-04 Depolarization induced cardiac
automaticity (human, animals)
ROlHL-17555-05 Distribution and metabolism of labeled
digitaloids (dogs, guinea pigs)
ROlHL-17629-03 Developmental aspects of cardiovascular
function (human, cats, rabbits)
P50HL-17646-04 0015 Study of ischemic heart disease -
Protecting ischemic myocardium in patients with evolving
myocardial Infarction
P50HL-1 7646-04 0017 Study of ischemic heart disease -
Dysrhythmia associated with acute myocardial infarction
(human, cat)
" P50HL-17648-04 0014 Study of ischemic heart disease ■
Antidysrhythmic drugs and mammalian cardiac Purkinje
fibers (sheep, dog)
P50HL-17651-04 0022 Ischemic heart disease specialized
center of research - Electrophysiology -Mechanism and
pharmacology of arrhythmias (human, dog)
P50HL-17655-04 0001 Study of ischemic heart disease -
Intravenous nitroglycerin-Ventricular function and infarct
size (human, dog)
P50HL17667-04 0018 Study of ischemic heart disease -
Arrhythmias in ischemic heart disease (human)
** P50HL17670-04 0011 Study of ischemic heart disease -
Pharmacology of ischemic myocardium (dogs)
P50HL-1768204 0001 Study of ischemic heart disease •
Studies in acute and chronic ischemic heart disease
(human)
R01HL1839804 Mechanisms of delayed and asymetric
ventricular conduction (human, dogs)
R01HL18769-04 Studies in survivors of lethal arrhythmias
(human)
ROlHL-18783-04 Detection and control of ventricular
premature beats (human)
R01HL18794-04 Prospective studies of conduction disease
(human)
ROlHL-18795-04 Ischemic arrhythmias-Effect of
autonomic tone (dogs, rats, guinea pigs)
ROlHL-18796-04 Experimental cardiac arrhythmias (dogs)
R01HL18805-04 0004 Sudden cardiac death and the
onset of myocardial infarction - Sudden death survivors-
Clinical follow-up and therapy (human)
ROlHL-19045-03 Electrophysiology of cardiac automaticity
(human, dogs)
ROlHL-192 16-03 Characterization of cardiac pacemaker
activity (cat. dog. rabbit)
ROlHL-19343-03 Behavioral influences on cardiac
contractility (monkeys)
R01HL19398-03 Regional conduction abnormalities and
arrhythmias (dogs)
ROlHL-19782-02 Pharmacologic studies on the ischemic
heart (dogs)
ROlHL-2021102 Role of taurine in the heart (dogs, rats,
mice)
ROlHL-2023802 Prospective bundle branch block study
(human)
ROlHL-20579-02 Synthesis of therapeutically important
alkaloids
** ROlHL-20754-02 Anesthetic-induced myocardial depression
(rabbits)
CAR
R23HL-21 196-02 Digitalis induced arrhythmia and NAO KO-
atpase activity (dogs)
** ROlHL-2122102 Clinical antiarrhythmic and
pharmacodynamic studies
** ROlHL-21670-01 Antiarrhythmic studies on 2-substituted
aminoindenes (dogs)
♦* ROlHL-21672-01 Antiarrhythmic drug action on VMAZ of
cardiac cells
ROlHL-2173501 Electrophysiology after healed myocardial
infarction (cats)
** ROlHL-21742-01 Frequency-dependent drug actions in
cardiac muscle (rabbits)
ROlHL-21812-02 Actions of drugs and ions on cardiac
membranes (rabbits, guinea pigs)
ROlHL-22135-01 Control of calcium fluxes across cardiac
membranes (dogs, rabbits, guinea pigs)
R01HL-22239-01 The molecular basis of electrical
excitability (chick embryos, rats)
ROlHL-22470-01 Liposome myocardial uptake in infarct
and ischemia (dogs, rats, mice)
ROlHL-22484-01 Neural control of cardiac conduction and
excitation (dogs)
ROlHL-22568-01 pH effect in heart cells-Influence of
cardiac drugs (tissue culture, rats)
** ROlHL-2286201 CNS-mcdiated effects of antiarrhythmic
drugs (dogs)
ROlHL-23071-01 Electrophysiology of lethal arrhythmias
(dog, human)
ROlHL-2359901 Mechanisms of ischemic rhythm
disorders (dogs)
** ROlHL-2362401 Effect of drugs on ischemic cardiac cells
(dogs, guinea pigs, pigs)
** ROlHL-2372601 Treatment of ventricular arrhythmias with
propranolol (human)
ROlHL-2397001 Mechanisms and control of sudden
cardiac death (human, dog)
CARDIOVASCULAR AGENTS,
ANTIATHEROGENIC AGENTS
SEE ALSO CHOLESTANE SERIES, CHOLESTEROL INHIBITORS
SEE ALSO LIPOGENIC INHIBITORS
** POlHL-06835-17 0064 Cardiovascular disease ■ Studies
in atherosclerosis (human, animals)
P50HL-14197-07 0006 Support for center of research on
arteriosclerosis - Diets and drugs affecting lipid
metabolism (human)
P50HL-14230-07 0094 A/S SCOR-Lipids, atherosclerosis
and thrombosis Studies of atherosclerosis and regression
(monkeys)
** R01HL15512-06 Drug treatment of stenosing primate
atherosclerosis (rabbits, monkeys)
CARDIOVASCULAR AGENTS,
ANTIHYPERTENSIVE AGENTS
SEE ALSO CARDIOVASCUUR AGENTS, VASODILATORS
R01HL00340-29 Electrolyte disturbance in cardiorenal
disease (human, dogs, rats)
POlHL-03174-23 0001 Mechanisms of acute vascular
reaction to injury • Response of the vascular intima to
injury (human, rats)
POlHL-0683517 0030 Cardiovascular disease ■ Synthesis
and pharmacology of angiotensin antagonists (rats, cats)
** POlHL-0683517 0037 Cardiovascular disease - Cardiac
hypertrophy in spontaneously hypertensive rat
POlHL-06835-17 0040 Cardiovascular disease ■ Benign
and malignant phase of renal hypertension (dogs)
P01HL06835-17 0045 Cardiovascular disease ■ Pressure-
volume-renin relationship in human hypertension
POIHL-06835-17 0046 Cardiovascular disease - Renin
activity during salt depletion in essential hypertension
(human)
POlHL-0683517 0053 Cardiovascular disease ■
Vasodilating drugs (human)
POlHL-06835-17 0057 Cardiovascular disease ■ Studies
on cardiac hypertrophy
POlHL-06835-17 0060 Cardiovascular disease -
Ventricular performance experimental models of arterial
hypertension (rats, dogs)
" ROlHL-07502-13 Phytochemistry of the genus thalictrum
(dogs, plants)
ROlHL-07835-17 Experimental hypertension and renal
circulation (rats, rabbits)
R01HL10711-12 Cooperative study of treatment of
hypertension (human)
ROlHL-10942-09 Study of genetic hypertension in rats
P01HL11414 11 0014 Thrombosis and atherosclerosis
program - Role of adrenal in human essential hypertensioij
POlHL-11678-11 0034 Cardiovascular dynamics and theif
control ■ Renal function curves in intact dogs
ROlHL-12648-09 Catecholamine metabolism in
hypertensive diseases (human)
ROlHL-1268409 Angiotensin I and converting enzyme in
hypertension (human, primates, dogs)
** PO1HL12738-10 0042 Physiologic pharmacology and itsi
clinical applications ■ Centrogenic cardiac arrhythmias
(cats) .
P01HL12738-10 0111 Physiologic pharmacology and itsi
clinical applications - Cardiovascular pharmacology (dogsM
POlHL-12738-10 0129 Physiologic pharmacology and ItsI
clinical applications ■ Receptor specificities and
metabolism of vasopressin analogs
R01HL12971-15 Reactions of alkoloids and their analog^
(contd)
indexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
Ctntitl ntuKi control of cmdiovasculai
CAR
ROIHl 1318709
tunction (call)
POIHI 13?6.' o; 001 1 Artaiiil wall in alhaioscletosis
Rota ol hypartanjion in atharojclarosis (human, monkay
dog)
ROIHL 1358706 Synthasis of tenin Inhibitors and analog
phojphalidas (rats)
ROIHL 13595 08 Renin and vascular hyper reactivity in
hypertension (human, rats)
ROIHL 13634 08 Renal hypertension in pregnancy (sheep)
ROIHL 1393606 Microvascular responses in hypertension
(human, rats)
ROIHL 14127 16 Methemoglobinemia and antihypertensive
drugs (cats. mice, rats)
P50HL 14159 08 0008 Spocialued center of research in
hypertension Renal tunction and sodium metabolism in
hypertension (rats, human, rabbits)
P50HL 1415908 0018 Specialized center of research in
hypertension Sympathetic nervous system in hypertension
(rats)
P50HL 1419208 0001 Specialized center of research in
hypertension Surgical and medical treatment of
renovascular hypertension (human)
P50HL 1419208 0002 Specialized center of research in
hypertension Hypertensive patients with renal artery
stenosis
P50HL 1419208 0003 Specialized center of research in
hypertension Prostaglandins as mediators of renin
secretion (human, dog)
P50HL14192.08 0005 Specialized center of research in
hypertension Nev« techniques for recognition of
renovascular hypertension (human, dogs)
POlHL-1438807 0179 Regulation of the circulation in
pathological states Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
POlHL-1438807 0194 Regulation of the circulation in
pathological states • Dopamine-beta-hydroxylase localization
and release in hypertension
ROlHL-1491306 Hypertension -Genetic influence of kidney
(rats)
R01HL14944-07 Renal vascular reactivity in hypertensive
patient
P01HL14985-07 0003 Adaptation to hypoxia - Hypoxia
and oxygen transport (human, dogs)
R01HL15047-06 Digital computer analysis of the
electrocardiogram (human)
ROlHL-1537806 Ultrastructure of antihypertensive
prostaglandins
ROlHL-15528-05 Renin kinetics in hypertensive and
uremic plasma (human, dogs)
R0IHL15580-06 Humoral control of pulmonary and
systemic circulation (animals)
R01HL15837-06 Renin and cardiac hypertrophy in
hypertension (rats)
ROlHL-1 7243-05 Cause of chronic experimental renal
hypertension (dogs, rabbits)
ROlHL-1 7335-05 Contractile properties of hypertensive
arterioles (rats)
ROlHL-1748704 Adrenergic-vasoregulation interactions in
hypertension (human)
ROlHL-1 7749-03 Adrenocortical factors in human
hypertension (human)
R01HL-I7754-03 Pathogenesis and prevention of
hypertension sequelae (rats)
POIHL-1787104 0009 Kidney, sodium, cardiac output,
arterioles and hypertension ■ Kidney, sodium, cardiac
output, arterioles and hypertension
ROlHL-17897-03 Synthesis of alpha and beta adrenergic
Mammalian renal microcirculation
antagonists
ROlHL-17902-04
(hamsters)
ROlHL-17947-04 Experimental renal and neurogenic
hypertension (human, animals)
ROlHL-18175-03 Drug taking for hypertension in a rural
community
P50HL18318-03 0001 Pathogenesis and complications of
hypertension - Core clinical program
P50HL- 183 18-03 0014 Pathogenesis and complications of
hypertension ■ Arterial metabolism and atherogenesis (rat
rabbit)
P50HL-18318-03 0019 Pathogenesis and complications of
hypertension - Renin-angiotensin system in blood pressure
regulation (human, rat. dog)
P50HL- 1 8323-04 0012 SCOR hypertension center - Renin
as a risk factor (human)
P50HL- 18323-04 0043 SCOR hypertension center -
Pharmacology-Renin-aldosterone mechanisms in essential
hypertension (human)
P50HL-18323-04 0045 SCOR hypertension center -
Laboratory programs-Prorenin (human)
R25HL-18406-03 Adherence to hypertensive medical
regimens (human)
R25HL-I84I4-03 Hypertension-Family strategies for
patient adherence
R25HL-18418-03 Role of a supporting partner in
adherence (human)
R25HL-I8424-03 Blood pressure education in an industrial
setting (human)
ROlHL-18579-03 Vasoactive hormones and blood pressure
regulation (dogs. rats, rabbits)
ROlHL-18629-04 Influence of aging and hypertension on
the myocardium (rats)
8S
ROIHL 18845 04 Regulation of renal circulation and lalt
excretion (rats, dogs)
' ROIHL 18891 02 Hectrolyte Intake and blood pressure in
hypertension (human)
ROIHL 19112 03 Atherosclerosis studios (monkeys)
ROIHL 1928/ 03 The antihypertensive function ol the
renal medulla (human, rats, rabbits)
P50HL 1936? 02 0010 A/S SCOR Alheroiclaroili In
nonhumon primates Antihypertensive therapy
Atherogenesis in experimental hypertension (baboon)
ROIHL 19538 03 Synthesis of potential antihypertensive
agents
ROIHL 19568 03 Hypertension Analysis of drug and
behavioral therapies (human)
ROIHL 20087 02 Developmental processes in pulmonary
hypertension (rats)
CAR
ROIHL 2019401
pressure (rats)
ROIHL 2024402
ROIHL 2024501
ROIHL 2024701
ROlHL-20248-01
ROIHL 2045503
Brain catecholamines in control of blood
he impact of hypertension information
The impact of hypertension information
The impact of hypertension information
The impact of hypertension information
Role of systemic hypertension on diabetic
retinopathy (human)
ROIHL 20542 03 Regional hemodynamics in spontaneous
hypertension (rats)
• POIHL 20552 02 0002 The development and regression of
cardiac hypertrophy Effect of treatment on the
hypertrophied left ventricle (rats)
POIHL 20552-02 0003 The development and regression of
cardiac hypertrophy - Muscle mechanics of the
hypertrophied left ventricle (rats)
ROIHL 205 7202 0003 Hemodynamic relations to
metabolism in hypertension Cardiac output and organ
blood flow in hypertension (rats)
ROIHL 20604-03 Sympathectomy-Cardiovascular and
molecular pharmacology (animals)
ROlHL-21274-01
analysis (human)
ROlHL-2139402
(rabbits)
ROlHL-21427-02
patients
R01HL-21877-01
ROlHL-22032-01
(human)
ROIHL 22216-02
Prorenin-Physiological and biochemical
Pulmonary angiotensin-converting enzyme
Behavioral changes in post infarction
Iso-renins in the hypertensive rat
Cardiovascular events in hypertensives
Vascular mechanisms in renal
hypertension (dogs)
ROlHL-22296-01 Autonomic mechanisms in man
ROlHL-22298-02 Origins of hypertension (human)
ROlHL-22341-01 Pathogenesis of atherosclerosis in rats
" R23HL-22345-02 0002 Behavioral cardiovascular
compliance strategies ■ Compliance with antihypertensive
medication regimens (human)
ROIHL-22417-01 Microprocessors in medical applications
(dogs)
ROlHL-22506-01 Hemodynamics of the clinical
hypertensions
ROlHL-22563-02 Prostaglandins, the kidney and
hypertension (rats)
ROlHL-22836-01 The spontaneously hypertensive kidney
(rats)
ROlHL-22868-01 Presynaptic regulatory mechanisms in
hypertension (rats, dogs)
ROlHL-22896-01 Immediate metabolic fates of kinins and
angiotensins (rat. rabbit, guinea pig)
ROlHL-23201-01
rats)
ROlHL-23603-01
disease (rats)
NOlHV-12434-11
population
NOlHV-12435-15
Mechanisms of hypertension (human.
Morphogenesis of hypertensive vascular
Therapy for hypertension in the general
Therapy for hypertension in the general
population (human)
NOlHV-12436-15 Hypertension therapy in the general
population (human)
N01HV-I2440-14 Therapy for hypertension in the general
population (human)
NOlHV-12442-14 Therapy for hypertension in the general
population (human)
NOlHV-2293114
population
NOlHV-22937-07
population
NOlHV-22938-11
population
NOlHV-22939-12
program center
NOlHV.22945-11
Therapy for hypertension in general
Therapy for hypertension in general
Therapy for hypertension in general
Hypertension detection and follow-up
Cooperative hypertension detection and
follow-up study (human)
NOlHV-22971-07 Prevention of coronary heart disease
(human)
NOIHV-22976-07 Multiple risk factor intervention trial.
prevention of coronary heart disease
NOlHV-22977-08 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22979-07 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22980-06 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22981-10 Intervention trial for the prevention of
coronary heart disease (human)
NOIHV ??<)8?0/ IntarvinlioM Irial lor prevantion ol
coronary heart diuaso (human)
NOIHV 229810/ Intervention trial for the prevtnlion of
coronary heart diteate (human)
NOIHV 33101 06 Development and condur.1 of a muHipIt
risk factor intervention trial (human)
NOIHV 33105 09 Intervention trial for prevention of
coronary heart disease (human)
NOIHV 33106 06 Inlervenlion trial (or the prevention of
coronary heart disease (human)
NOIHV 33108 04 Prevention of coronary heart disease
(human)
NOIHV 33109 04 Intervention trial for the prevention of
coronary heart disease (human)
NOIHV 331 10 04 Prevention of coronary heart disease
(human)
NOIHV 42929 08 Risk factor intervention Irial for the
prevention of CHD (human)
NOIHV 42930 09 Risk factor intervention trial for the
prevention of CHD (human)
NOIHV 42931 07 Risk factor inlervenlion trail for the
prevention of CHD (men)
NOIHV 42932 05 Risk factor intervention trial (or the
prevention of CHD (human)
N01HV4293309
disease (human)
NOIHV 6290000
(human)
N01HV7291502
population
NOIHV 82913 00
Multiple risk factors in coronary heart
Study of breast cancer and reserpine use
Therapy for hypertension in the general
Demonstration programs in hypertension
control in the work setting (human)
N01HV82915-01 Therapy for hypertension in the general
population (human)
CARDIOVASCULAR AGENTS, ARRHYTHMIC
AGENTS
ROlHL-17555-05 Distribution and metabolism of labeled
digitaloids (dogs, guinea pigs)
ROIHL 1879504 Ischemic arrhythmias -Effect of
autonomic tone (dogs, rats, guinea pigs)
ROIHL 19487-03 Cardiac actions of digitalis (dogs, cats)
R23HL 21196-02 Digitalis induced arrhythmia and NAO KO-
atpase activity (dogs)
R01HL-21922-01 Transient currents induced by
strophanthidin in the heart
CARDIOVASCULAR AGENTS, CARDIOTONIC
AND CARDIOPROTECTIVE DRUGS (GENERAL)
POlHL-06285-18 0153 Cardiovascular-respiratory
physiology and biochemistry Myocardial mechanics and
pharmacology in isolated papillary muscle (animals)
POlHL-0628518 0155 Cardiovascular-respiratory
physiology and biochemistry - Therapeutic alterations,
contractile state in heart failure
POlHL-06285-18 0186 Cardiovascular-respiratory
physiology and biochemistry - Leukocyte hormone receptors
and cyclic nucleotides (tissue culture)
** POlHL-06296-18 0005 Cardiovascular and pulmonary
adaptation to stress - Regulation of ventricular
performance (animals)
P01HL06296-18 0007 Cardiovascular and pulmonary
adaptation to stress - Cardiovascular control during
isometric exercise (cats)
POIHL-06312-17 0036 Surgical cardiology - Experimental
studies of cardiac compliance (dogs)
** POlHL-06370-17 0014 Cardiopulmonary and renal
pathology research center ■ Quantitative morphology in
cardiac disease (human, rats, dogs)
POlHL-12373-10 0013 Cardiopulmonary physiology and
pathophysiology - EHects of cardiovascular drugs on left
ventricular function (dogs)
ROlHL-1241510 Evaluation of left ventricular function
(dogs, rabbits)
Physiologic pharmacology and its
Clinical pharmacology of cardioactive
P01HL-12738-I0 0001
clinical applications
drugs (human)
POlHL-12738-10 0044
clinical applications
^&^ides routine methodokjgy OR covers only general protects which preclude indexine
"Onented significantly to atnve subject.
at the specific level.
M Grant has subprojeds descnbing specific research aspects
See Appendix for investigators name and grant number
Physiologic pharmacology and its
Cardioactive drugs and
electrophysiological properties of cardiac cells (sheep)
POlHL-12738-10 0107 Physiologic pharmacology and its
clinical applications - Blood superfused cardiac fibers
(dogs)
POlHL-12738-10 0109 Physiologic pharmacology and its
clinical applications - Effects of calcium blockers on
skeletal and cardiac muscle (cats)
POlHL-13108-09 0017 Clinical heart transplantation -
clectrophysiology of the transplanted denervated human
heart
ROlHL-13636-08 Effects of pharmacologic agents on heart
metabolism (human, rodents)
ROlHL-1470607 Fetal hearts in organ culture (mice)
ROlHL-15247-05 Extending the life of implanted
pacemakers (dogs, human)
ROlHL-15416-06 Cardiovascular control in normal and
disease states (dogs, baboons)
ROIHL-15498-06 Effects of physical training on heart
(rats)
ROlHL-15676-06 The role of occult myocardial failure in
human shock (human, dogs)
R01HL-I6052-05 Cardiac glycosides-Mechanism of
inotropic action (dogs)
(contd)
*-^.MBM^^mmm,mM^
CAR
POlHL-161 17-05 0001 Ion movements and membranes in
cardiovascular control - Developmental studies of
contractile cell junctions (rats, rabbits, elasmobranch)
P01HL161 17-05 0005 Ion movements and membranes in
cardiovascular control - Properties of isolated cell
membranes (rabbits, cats)
ROlHL-16152-06 Electrophysiology of neonatal to adult
heart (cats, frogs, guinea pigs)
ROlHL-16240-05 The cardiac histamine receptor (rabbits.
guinea pigs) . ^ ^
ROlHL-16657-06 Innervation of coronary arteries and heart
(rats)
ROlHL-167 10-03 Myocardial subcellular localization of
calcium (dogs)
ROlHL-17631-05 Experimental congestive heart failure and
hypertrophy (cats)
P50HL-17646-04 0001 Study of ischemic heart disease -
Core clinical investigation unit
P50HL-1 7646-04 0003 Study of ischemic heart disease ■
Core pathology facility (human, dogs)
P50HL-17646-04 0013 Study of ischemic heart disease -
Maintenance of myocardial vascular integrity after
revascularization (dogs)
* P50HL-17646-04 0015 Study of ischemic heart disease -
Protecting ischemic myocardium in patients with evolving
myocardial infarction
P50HL17655-04 0001 Study of ischemic heart disease -
Intravenous nitroglycerin-Ventricular function and infarct
size (human, dog)
P50HL-17665-04 0020 Study of ischemic heart disease -
Ischemic injury to myocardium during measured states of
ischemia (human)
P50HL-17565-04 0021 Study of ischemic heart disease ■
Identification, prevention -Myocardial ischemia in
cardiopulmonary bypass (dog)
** P50HL-17667-04 0022 Study of ischemic heart disease -
Preventing myocardial injury in surgery using
cardiopulmonary bypass (human, rat)
P50HL-17669-04 0006 Ischemic heart disease center
(SCOR) - Studies of hypoxic, acidotic and ischemic cardiac
muscle (dogs)
ROlHL-17736-04 Metabolic change during cardiac
ischemia (rats, dogs)
P01HL-18646-03 0010 Studies basic to heart
transplantation - Development and study of a heart
preservation chamber (dogs, sheep)
ROlHL-18711-03 Electrophysiology of heart cells (rats,
chicks)
** ROlHL-19044-03 Effect of drugs on development of
cardiac failure (cats)
ROlHL-19148-03 Myocardial organelle lipid structure and
function (dog, rat)
ROlHL-19182-03 Surgical aspects of myocardial
hypertrophy (dogs)
ROlHL-19325-03 Phosphodiesterase inhibition and muscle
contraction
•* ROlHL-1941403 Protection of myocardium during cardiac
surgery (dogs, cats, human)
** ROlHL-20283-02 Maintenance of cellular integrity in
ischemic hearts (cats)
ROlHL-20630-03 Development of a pulsed Doppler velocity
detector (human, animals)
** ROlHL-21209-02 Alterations of metabolism in ischemic
myocardium (sviine)
ROlHL-21367-02 Polyether ionophores -Synthesis of XbJ/A
and analogs
** ROlHL-21457-01 C(17)-side group geometry and
cardenolide activity (cats, guinea pigs)
ROlHL-21672-01 Antiarrhythmic drug action on VMAZ of
cardiac cells
ROlHL-21719-01 Computed cardiac tomography in infarct
sizing (dogs, human)
** ROlHL-21786-01 Long-term effects of myocardial
protection (dogs, rats)
ROlHL-21812-02 Actions of drugs and ions on cardiac
membranes (rabbits, guinea pigs)
ROlHL-21922-01 Transient currents induced by
strophanthidin in the heart
ROlHL-22008-01 Left ventrivular calcium content and
contractility (rats)
ROlHL-22269-01 Excitation-contraction coupling in
enlarged hearts (rabbits) , ,
R01HL-22470-01 Liposome myocardial uptake in infarct
and ischemia (dogs, rats, mice)
•• ROlHL-22566-01 Mesoionic purinones as
phosphodiesterase inhibitors
** ROIHL 22778-01 Total synthesis of natural cardiotonic
ionophores
ROlHL-23138-01 Myocardial ischemia (dogs, rats, chick
embryo)
ROIHL 23599-01 Mechanisms of ischemic rhythm
disorders (dogs)
CARDIOVASCULAR AGENTS, VASOACTIVE
AGENTS (GENERAL)
SEE ALSO PEPTIDES. VASOACTIVE PEPTIDES
ROlHL-03181-21 0027 Hemodynamics as applied to
surgical problems - Hemodynamic studies of the Gl tract
(dogs) , .
•• ROlHL-05883-18 0001 Reflex control of resistance and
capacitance vessels • Naturally occurring vasoactive
substances and the vascular neuroeffectors (dog)
86
POlHL-06285-18 0132 Cardiovascular-respiratory
physiology and biochemistry - Umbilical-placental
circulatory responses (lambs)
POlHL-06285-18 0186 Cardiovascular-respiratory
physiology and biochemistry - Leukocyte hormone receptors
and cyclic nucleotides (tissue culture)
ROlHL-06736-18 Biogenic-mechanical factors in
microcirculation (rats, gerbils)
POlHL-06835-17 0027 Cardiovascular disease - Studies
in thrombosis-cross-linking of fibrinogen (human)
ROlHL-083 11-14 Effects of drugs upon myocardial hypoxia
(dogs, turtles)
R01HL-08570-15 Pharmacologic and reflex influence on
vascular tone (dogs, rabbits)
POlHL-08805-15 0048 Regulation of ventilation and
pulmonary circulation ■ Permeability of alveolo -Capillary
membrane in normal pulmonary hypertensive lung
POlHL-10436-13 0014 A multidisciplinary study of
congenital heart disease Cardiovascular pharmacology
(dog)
POlHL-10436-13 0015 A multidisciplinary study of
congenital heart disease - Fetal and neonatal
cardiovascular physiology (sheep)
ROlHL-10881-13 Structure and function of
microcirculation (hamsters, rats, cats, dogs)
* POlHL-11310-12 0065 Mechanisms of cardiovascular
disease - Algorithms for arterial pressure by automatic
vasoactive agents control (human)
POIHL-11678-11 0059 Cardiovascular dynamics and their
control - Basic hemodynamics (dogs, rats)
■* ROlHL-11802-10 Cardiovascular surgical research (dogs,
sheep, swine, cats, monkeys)
ROlHL-1 1906-11 Comparative study of heart function
(cats, rats, hedgehogs, squirrels)
ROlHL-12415-10 Evaluation of left ventricular function
(dogs, rabbits)
ROlHL-12421-10 Pathophysiology of circulatory shock
(dogs, baboons)
ROlHL-12493-10 Bioengineering analysis of microvascular
function (cats, rabbits)
ROlHL-12607-10 Dynamics of pulsatile blood flow (human,
dogs, rats)
ROlHL-126 14-09 Microcirculatoty control mechanisms and
hypertension (bats, rats)
ROlHL-12677-10 Surgical physiologic studies of isolated
kidneys (dogs, rats)
ROlHL-12684-09 Angiotensin I and converting enzyme in
hypertension (human, primates, dogs)
POlHL-12738-10 0111 Physiologic pharmacology and its
clinical applications - Cardiovascular pharmacology (dogs)
ROlHL-12792-09 Local control of the microcirculation
(hamsters, rats)
ROIHL 13187-09 Central neural control of cardiovascular
function (cats)
POlHL-13262-07 0011 Arterial wall in atherosclerosis -
Role of hypertension in atherosclerosis (human, monkey,
dog)
** POlHL-13262-07 0018 Arterial wall in atherosclerosis -
Vasoactive factors of human plasma
ROlHL-13315-08 Disposition of vasoactive hormones in
mammalian lung (rats, rabbits, human)
ROlHL-13437-09 Physical and mechanical parameters in
the microcirculation (animals)
ROlHL-13936-06 Microvascular responses in hypertension
(human, rats)
M P50HL-141 87-07 Pulmonary SCOR -Chemical mediators in
pulmonary vascular responses
** P50HL-14187-07 0014 Pulmonary SCOR -Chemical
mediators in pulmonary vascular responses - Metabolism
and actions of vasoactive peptides in lung (human,
mammals)
P50HL-14187-07 0015 Pulmonary SCOR -Chemical
mediators in pulmonary vascular responses -
Pathophysiologic responses of pulmonary capillary bed
(dog, human)
P50HL-14187-07 0016 Pulmonary SCOR -Chemical
mediators in pulmonary vascular responses - Core
pathology service (dogs, rabbits, human)
" P50HL-142 18-07 0017 Pulmonary SCOR-Newborn lung
center - Transvascular fluid exchange, vasoactive mediators
in RDS (sheep, cat)
ROlHL-14306-07 Quantification of arterial pressure control
(dogs)
POlHL-14388-07 0154 Regulation of the circulation in
pathological states ■ Energetics of smooth muscle
contraction (rats)
POlHL-14388-07 0163 Regulation of the circulation in
pathological states - Adrenergic receptors in coronary
vessels (dogs)
POlHL-14388-07 0180 Regulation of the circulation in
pathological states - Regulation of cerebral blood flow
(dogs, monkeys)
" POlHL-14388-07 0186 Regulation of the circulation in
pathological states - Angiotension in modulation of
neurogenic vasoconstriction
POlHL-14388-07 0187 Regulation of the circulation m
pathological states - Histamine and circulatory control
POlHL-14388-07 0196 Regulation of the circulation in
pathological states - Altered vascular responsiveness in
spontaneous hypertension (rats)
CAR
POlHL-14388-07 0197 Regulation of the circulation in
pathological states - Altered vascular reactivity in
pathogenesis of spontaneous hypertension (rats)
POlHL-14388-07 0198 Regulation of the circulation in
pathological states - Humoral factors in vascular reactivity
in spontaneously hypertensive rats
' POlHL-14388-07 0199 Regulation of the circulation in
pathological states - Adrenergic stimulation in
spontaneously hypertensive rats
POlHL-14388-07 0210 Regulation of the circulation in
pathological states - Effects of dietary sodium on blood
pressure and vascular reactivity
POlHL-14388-07 0220 Regulation of the circulation in
pathological states - Pharmacology of the coronary
circulation in man
POlHL-14388-07 0225
pathological states
Regulation of the circulation in
Release of renal prostaglandins by
saluretic-diuretic agents (dogs)
POlHL-14388-07 0229 Regulation of the circulation in
pathological states - Mechanism of postural hypotension
(human)
ROlHL-14944-07 Renal vascular reactivity in hypertensive
patient
POlHL-14985-07 0012 Adaptation to hypoxia - Direct
effect of hypoxia on pulmonary vascular smooth muscle
(rats, dogs)
POlHL-14985-07 0014 Adaptation to hypoxia - High
altitude pulmonary edema (human, rats, dogs)
ROlHL-15124-05 Genesis of hypertension in renal disease
(human, dogs)
ROlHL-15416-06 Cardiovascular control in normal and
disease states (dogs, baboons)
ROlHL-15447-06 Vascular role of prostaglandin and cyclic
nucleotides (rats)
ROlHL-15562-05 Regulation of skeletal muscle blood flow
(dogs) .
ROlHL-15607-06 Physiological control of splanchnic
circulation (dogs)
POlHL-15832-06 0007 Chemical-structural predispositions
to lung injury - Inactivation of vasoactive agents by the
lung (human, rats. cats, dogs)
' POIHL- 15832-06 0011 Chemical-structural predispositions
to lung injury - Interaction of cell receptors with vasoactive
agents in pulmonary vascular bed
POlHL-15832-06 0012 Chemical-structural predispositions
to lung injury - Contractile structures and contractility in
cells of lung respiratory tract
ROIHL- 16094-06 The dynamics of microcirculatory function
(dogs)
ROlHL-16454-03 Vascular muscle reactivity in
hypertension (human, rats)
ROIHL- 16489-04 Renal prostaglandins-Synthesis and
function (human, dogs, rats)
ROlHL-16588-05 Collagen synthesis in atherosclerosis
(dogs. rats, rabbits, human)
ROlHL-16648-16 Integrated control of cardiovascular
activity (cats)
ROlHL-16666-05 Micropinocytosis in isolated capillary
endothelium
POlHL-16910-05 0008 Regulation of the peripheral
circulation - Circulation to bone (dogs, baboons)
POlHL-17421-05 0001 Regulation and exchange in the
microcirculation - Mass transfer and microcirculatory
function (rats)
ROlHL-17487-04 Adrenergic-vasoregulation interactions in
hypertension (human)
ROlHL-17516-04 Role of androgen as a risk factor in
atherogenesis (human, animals)
P50HL-17646-04 0012 Study of ischemic heart disease
Role of microcirculation in progression of myocardial
ischemic injury (rat)
** P50HL-17646-04 0016 Study of ischemic heart disease
Humoral factors in ischemic heart rhythm, mechanical
performance (dog. rabbit)
P50HL-17648-04 0023 Study of ischemic heart disease
Chemical mediators of inflammation in acute myocardial
infarction (mammals)
P50HL-17651-04 0015 Ischemic heart disease specialized
center of research - Peripheral circulation in acute
myocardial ischemia and infarction (human)
P50HL-17682-04 0021 Study of ischemic heart disease ■
Prostaglandin biosynthesis in blood vessels from ischemic
myocardium (rat. sheep)
ROlHL-17768-04 Development of collateral ventilation
(dogs, fish, horses)
POlHL-17812-04 0007 Thrombosis and plasma proteins ■
Blood components -Response to endotoxin (dogs, baboons)
ROlHL-17932-04 Blood flow regulation in muscle (cats)
ROlHL-17947-04 Experimental renal and neurogenic
hypertension (human, animals)
R01HL-18002-03 Circulatory shock, trauma and RE-system
function (rats)
ROlHL-18015-03 Pharmacologic studies on vascular
smooth muscle (dogs, rats)
** ROlHL-18070-04 Regulation of intrapulmonary airways
and vessels (human, animals)
ROlHL-18080-03 Extrinsic control of intestinal
microcirculation (dogs)
ROIHL 18191-04 Models of hypoxic pulmonary
hypertension (cattle, minipigs)
** ROlHL-18199-03 Effects of ions on vascular reactivity
(contd)
•Excludes routine methodokigy OR covers only general projects which preclude
"Oiwnted significantly to above subject.
indexing at the specific level.
M Grant has subprojects describing specific research aspects
See Appendix for Investigators name and grant number.
Contmlltd Intritlisu* rtltase of
CAR
R01HII8»»43
pn)il*|l(ndlns
PSOHl 1831803 0014 Pttho|(nasis and complications ot
hypactansion Artarial malabolism and athatoganasis (lat
rabbit)
** P60HI 18318 03 OOIS Palhogenasis and complications of
hypartansion Cultuiad smooth muscle calls and
miciovassal malabolism (mammals)
** ROIHL 18489 03 Hamodynamic intatactions of vasoactiva
chamicals Uats)
POIHL 185;S03 0001 Mechanisms of vascular cliangas
in hypertension Arteries and resistance vessels in
hypertension (pigs, rats)
POIHL 185;!) 03 0007 Mechanisms ot vascular changes
in hypertension Microscopy ot hypertensive arterial lesions
(rats)
'* ROIHL 1857903 Vasoactive hormones and blood pressure
regulation (dogs, rats, rabbits)
ROIHL 18657 03 Pharmacologic studies on neurogenic
digitalis effects (human, cats, dogs)
ROIHL 1871804 Prostaglandin precursors and vascular
reactivity (dogs)
P50HL 1882803 0002 Specialised center of research in
thrombosis Endothelial cell biology (human, guinea pig)
R01HL18831 03 Microscopy ot spontaneously hypertensive
arterial lesion (rats)
ROIHL 1886602 Microvascular flo»», volume, and
reactivity (rats, cats)
ROIHL 18932-03 Brain microcirculation observed in vivo
after trauma (mice)
** ROIHL 18936 02 Heart preservation and transplantation
studies (rat)
ROIHL 18977 03 Non-invasive diagnosis of peripheral
arterial disease (human, dogs)
R01HL1903903 Circulation studies by one vs two circuit
model (dogs)
R01HL1906603 Synthesis and evaluation of
prostaglandin metabolites (guinea pigs)
ROIHL 19082-01 Hypoxiainduced relaxation of vascular
smooth muscle
ROIHL 1913404 Angiotensin, prostaglandins, adrenergic
interactions (rats, rabbits)
P50HL-19185-02 0006 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Evaluation of risk factors
in neonatal respiratory distress (human, sheep)
ROlHL-19225-02 0003 Types and mechanims of
pulmonary hypertension - Cardiopulmonary function in pigs
and rats
PO1HL1924202 0001 Study of vascular smooth muscle ■
Energy metabolism and protein turnover in vascular smooth
muscle (rats)
** P01HL19242-02 0003 Study of vascular smooth muscle •
Vasoactive metabolites from vascular muscle and
parenchymal tissue (animal)
POlHL-19242-02 0009 Study of vascular smooth muscle •
Electrophysiology of vascular smooth muscle (rats, chick
embryo)
•* ROlHL-19275-03 Characterization of collateral blood
vessels (dogs)
ROIHL- 19298-03 Pulmonary hemodynamics (dogs, cats)
ROlHL-19673-03 Surgical aspects of shock and hypoxia
(dogs, monkeys, rats)
ROlHL-19870-03 Hypertensive progeny-Physical and
humoral precursor search
R01HL19997-02 Prostaglandin precursors and intestinal
vasculature (cats, rabbits)
ROlHL-20054-02 Cultured blood vessel cells-
Pathophysiology (human, animals)
ROlHL-20328-01 Noninvasive assessment of autonomic
cardiac control (dogs)
ROlHL-20429-03 Study of effects of diabetes reactivity
(miniature pigs, rats)
POlHL-20581-01 0001 Vascular neuroeffector
mechanisms in health and disease ■ Vascular neuroeffector
mechanism (rabbits)
POlHL-20581-01 0003 Vascular neuroeffector
mechanisms in health and disease - Cerebrovascular
neuroeffector characteristics (animals)
ROlHL-20787-02 Thromboxanes and prostaglandins-
Biochemical pharmacology (rabbits, human)
ROlHL-2092402 Atherosclerosis and arterial cell functions
(human, rabbits)
ROlHL-20989-01 Pathophysiology of bronchial asthma
(sheep, dogs)
POlHL-21016-02 0013 Sickle cell anemia and other
hemoglobinopathies ■ Microcirculatory response to sickle
cell treated with antisickling agents (rats)
* R23HL21203-02 Effect of vasoactive agents on leftto-
right shunts (lambs)
ROlHL-21221-02 Clinical antiarrhythmic and
pharmacodynamic studies
ROlHL-21272-02 Sodium homeostasis and renal
prostaglandins (dogs)
R23HL-2 1298-02 Coronary vasomotion (dogs, pigs)
R23HL-21382-02 Effect of pressure on renal blood flow
and function (dogs)
ROIHL-21429-02 Transport of LDL in arterial wall (human,
mammals)
R23HL-21434-02 Intrinsic control of coronary blood flow by
chemicals (guinea pigs)
ROlHL-21438-02 Structure and permeability of arterial
endothelium (pigs)
S7
Regional non ischemic myocardial
ROIHL 21657 01
hypoxia (dogs)
ROIHL 71670 01 Antiarrhythmic studies on ? substitutid
ammoindenes (dogs)
ROIHL 21851 01 Cerebral microcirculation in aiparimontal
hypartansion (cats, rabbits)
R23HL 2207501 Matabolism of arachidonic add in blood
vessels (chickens, mammals)
** ROIHL 22077 01 Vasoactiva amine disposition in cultured
endothelium (rabbits)
ROIHL 22087 02 Humoral mediators of pulmonary
inflammation (guinea pigs)
ROIHL 221 77 02 Mechanisms of control of pulmonary
smooth muscle (dogs)
ROIHL 2221602 Vascular mechanisms in renal
hypertension (dogs)
ROlHL-22223-01
models)
ROIHL 2246302
edema (rats)
ROIHL 2256101
circulation (cats)
ROIHL 2256902
forces (dogs, cats)
POlHL-226 19-01 0008 Cellular
failure Molecular mechanisms amflhmnmatkbOtticMe
responsiveness in VSM (dogs)
ROlHL-22836-01 The spontaneously hypertensive kidney
(rats)
R23HL-22972-01
(rats, hamsters)
R01HL-2317I01 Coronary collateral circulation in
myocardial ischemia (dog. pig. rat. human)
ROlHL-2321001 Biology of normal and hypertrophied
pulmonary vessels (cat, human)
ROlHL-23239-01 Functional characteristics of pulmonary
vascular smooth muscle (dogs)
ROlHL-23312 01 Hemodynamics and vasoactivity in renal
hypertension (human, dogs)
ROlHL-23542-01 Pulmonary vascular smooth muscle cell
dynamics (rat, rabbit)
ROlHL-23604-01 Hepatic microvascular regulatory
mechanisms (rat)
CARDIOVASCULAR AGENTS, VASODILATORS
SEE ALSO CARDIOVASCUUR AGENTS, ANTIHYPERTENSIVE
AGENTS
ROlHL-03181-21 0025 Hemodynamics as applied to
surgical problems - Vascular stenosis (dogs)
ROlHL-03941-18 Uterine blood flow and changes in
pregnancy (sheep)
The cardio pulmonary junction (dogs,
Pinocytotic vesicles and pulmonary
Hormonal control of mesenteric
Intestinal secretion-Capillary and tissue
Microcirculatory function in hypotension
Immunologic mechanisms in
Transplantation biology and
POlHL-06314-17 0065
cardiovascular disease
clinical transplantation
POlHL-06664-17 0034 Cardiopulmonary function in
remediable vascular disease - Role of hyperosmolar agents
in ischemic heart disease (dogs)
P01HL-06664I7 0043 Cardiopulmonary function in
remediable vascular disease - Alveolar hypoxic
vasoconstriction-Control and clinical significance (dog,
human)
POlHL-06835-17 0037 Cardiovascular disease - Cardiac
hypertrophy in spontaneously hypertensive rat
POlHL-06835-17 0053 Cardiovascular disease -
Vasodilating drugs (human)
POlHL-07896-15 0019 Environmental biomedical research
program - Hyperoxic myopia (human)
POlHL-10342-13 0019 The integrated function of
respiration and circulation - Cerebral circulation and
metabolism (dogs)
ROlHL-10384-13
(animals)
ROIHL- 108 34-09
Blood flow and nucleotide metabolism
Fetal and neonatal pulmonary circulation
(goats)
R01HL-I2322-10 Extrinsic factors influencing myocardial
performance (dogs, swine)
POlHL-123 73-10 0013 Cardiopulmonary physiology and
pathophysiology - Effects of cardiovascular drugs on left
ventricular function (dogs)
ROlHL-12792-09 Local control of the microcirculation
(hamsters, rats)
P50HL-14187-07 0012 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses ■ Vasoactive
mediators in pulmonary disease (human, animal)
P50HL- 142 17-08 0051 Specialized center of research in
thrombosis - Microcirculation section (bat, hamster)
POlHL-1438807 0229 Regulation of the circulation in
pathological states - Mechanism of postural hypotension
(human)
POlHL-14985-07 0003 Adaptation to hypoxia - Hypoxia
and oxygen transport (human, dogs)
POlHL-14985-07 0005 Adaptation to hypoxia - Control
mechanisms in the pulmonary microcirculation (animals)
POlHL-14985-07 0015 Adaptation to hypoxia - Pregnancy
at high altitude (human, animals)
ROlHL-15231-05 Mechanisms of hemodynamic changes
during digestion (dogs)
ROlHL-15580-06 Humoral control of pulmonary and
systemic circulation (animals)
ROlHL-16066-05 Studies on neurogenic control of the
circulation (human, dogs)
CAR
POIHI 16910 05 0001 Regulation of Ihg ptripharil
circulation Uuinlililivt itudiat ot microcirculatory control
(baft)
P50HI 1/655 04 0014 Study of iichemic heart dItUM
Blood flow and gas teniion in myocardial iichemia and
infarction (dog. monkey)
P50HI 17682 04 0021 Study of ischemic heart ditaau
Prostaglandin biosynthesis in blood vestals from itchemic
myocardium (rat, sheep)
ROIHl 18070 04 Splanchnic hemodynamics in man
' ROIHL 18792 04 Vasodilation and mlcrovtlcular oxygen
delivery (dog, hamster)
P50HL 1831803 0019 Pathogenesis and complications of
hypertension Renin angiotensin system in blood pressure
regulation (human, rat, dog)
ROIHL 18467 03 Fingertip blood flow in normals and
Raynaud's disease (human)
ROIHL 18882 02 Hormones in hypertension (human)
ROIHL 18994 03 Substance P Occurrence, pharmacology
and physiology (mammals non human, human)
ROIHL 19057 03 Catecholamines and cyclic AMP in
cardiovascular system (rats, dogs)
ROIHL 1906203 Pharmacologic control of mast cell
phosphodiesterase (human, rats)
ROIHL 19218-03 Local regulation of coronary flow by
prostaglandins (rabbits)
ROIHL 19225 02 0001 Types and mechanims of
pulmonary hypertension Structural changes (human.
animals)
ROIHL 19428-03 Role of angiotensin sensitivity in renin
release (human)
ROIHL 20194-01
pressure (rats)
ROIHL 20579-02
alkaloids
ROlHL-20895-03 0008 Cineangiographic studies of
cardiovascular system Intercoronary anastomotic
circulation-Stenosis and occlusion (dogs)
POlHL-21016 02 0008 Sickle cell anemia and other
hemoglobinopathies The clinical variations of sickle eel
anemia
ROlHL-21034-01 Compensatory responses to arterial
occlusion (dogs)
R23HL 21203-02 Effect of vasoactive agents on lett-to-
right shunts (lambs)
ROlHL-2180001
excretion
R23HL-22309-01
Brain catecholamines in control of blood
Synthesis of therapeutically important
immature dogs
ROlHL-22573-01
Angiotensin effects on water intake and
Cardiovascular pharmacodynamics in
*£»dudes nutlne methodotogy OR covers only general projects which preclude indexing
Oiented significantly to above subject.
at the specific level.
M Grant has subprojects describing specific research aspects
See Appendix for investigator's name and grant number.
Treatment of post surgical
vasoconstriction (dogs, monkeys, human, rats)
ROlHL-2250301 Trace metals, vascular activity and
hypertension (rats)
ROlHL-2261201 Stabilized prostacyclins to treat vascular
disease
R23HL-22975-01 Dynamics of autoregulation of muscle
blood flow (dogs)
ROlHL-2297701 Role of vasoconstrictor mechanisms in
heart failure (human, dogs)
CARDIOVASCULAR AGENTS, VASODILATORS,
CORONARY
ROlHL-00487-29 Vasomotor tone and venous return
(human, dogs, monkeys )
POlHL-04664-18 0010 Cardiovascular and lung dynamics
- Left ventricular dynamics (human)
POlHL-04664-18 0011 Cardiovascular and lung dynamics
• Detection of abnormal segments of the human ventricle
by measure of asynergy
POlHL-04664-18 0012 Cardiovascular and lung dynamics
- Quantitative single plane left ventricular angiography
(human)
P01HL04664-18 0013 Cardiovascular and lung dynamics
Ventricular function in coronary disease using NTG and
ventriculograms (human)
POlHL-04664-18 0014 Cardiovascular and lung dynamics
■ Clinical application of computer analysis of ventricular
wall motion
POlHL-06312-17 0016 Surgical cardiology ■ Effect of
hydralazine on infarct size following coronary occlusion
(human)
ROlHL-07139-17 Cardiodynamics and metabolism of
congestive failure (human, dogs)
ROlHL-08508-15 Cardiac conductivity and automaticity
(human, dogs, rabbits)
ROlHL-08892-10 Cooperative study of drugs and coronary
heart disease
ROIHL- 10384- 13 Blood flow and nucleotide metabolism
(animals)
POlHL-10436-13 0002 A multidisciplinary study of
congenital heart disease - Myocardial performance,
metabolism and ultrastructure (human, cats, rats)
POlHL-11310-12 0056 Mechanisms of cardiovascular
disease ■ Cardiac output response to blood pressure
reduction in infants (human)
POlHL-11310-12 0057 Mechanisms of cardiovascular
disease - Blood pressure reduction after heart surgery In
adults (human)
'* P01HL11310-12 0058 Mechanisms of cardiovascular
disease - Dynamic response to vasodilating agents
postoperatively (human)
ROlHL-12777-09 Mechanisms in cardiac performance
(dogs, human)
(contd)
CAR
ROlHL-14717-06 Hemodynamics and heart structure-
Ventricular overload (dogs)
** ROlHL-15522-06 Influence of mannitol on ischemia
cardiac muscle (dogs, cats, rats)
R01HL15837-06 Renin and cardiac hypertrophy in
hypertension (rats)
POlHL-161 17-05 0005 Ion movements and membranes in
cardiovascular control ■ Properties of isolated cell
membranes (rabbits, cats)
POlHL-16117-05 0007 Ion movements and membranes in
cardiovascular control - Physiological and molecular
properties of ionophores (dogs, rabbits)
ROlHL-16292-05 0010 Surgery and non-obstructive
coronary insufficiency ■ Effects of exercise on flow
distribution (dogs)
** ROlHL-164 12-04 Release of nucleosides from the ischemic
heart (human, dogs)
** ROlHL-16760-05 Dynamic control of coronary blood flow
(dogs)
P01HL16910-05 0002 Regulation of the peripheral
circulation • Coronary circulation (dogs)
ROlHL-17459-03 Myocardial ischemia (dogs)
ROIHL-17631-05 Experimental congestive heart failure and
hypertrophy (cats)
P50HL-17646-04 0015 Study of ischemic heart disease ■
Protecting ischemic myocardium in patients with evolving
myocardial infarction
P50HL-1764604 0016 Study of ischemic heart disease ■
Humoral factors in ischemic heart rhythm, mechanical
performance (dog, rabbit)
P50HL-1765104 0002 Ischemic heart disease specialized
center of research ■ Reduction of myocardial ishemic injury
by pharmacologic agents (human, dog)
P50HL-17651-04 0045 Ischemic heart disease specialized
center of research • Peripheral vascular studies -
Pharmacology (dogs, human)
P50HL-17655-04 0001 Study of ischemic heart disease •
Intravenous nitroglycerin -Ventricular function and infarct
size (human, dog)
P60HL- 17682-04 0005 Study of ischemic heart disease -
Regional myocardial perfusion deficits and segmental
contraction disorders in man
P50HL1768204 0020 Study of ischemic heart disease ■
Nucleotide and nucleoside metabolism in ischemic
myocardium
ROlHL-17759-03 Studies of myocardial reactive hyperemia
(dogs, human)
R01HL18024-03 Regional myocardial flow and function
relationships (dogs)
ROlHL-18190-03 Myocardial blood flow in acute
myocardial infarction (human, dogs)
ROlHL-18468-03 The distribution of flow in the
myocardium (dog, pig)
R01HL18537-04 Regional blood flow after acute
myocardial injury (dogs)
R01HL19089-03 Diastolic properties of the left ventricle
(human, dogs)
** ROlHL-19202-03 Adenosine, prostaglandins in relation to
coronary flow (guinea pigs)
ROlHL-19275-03 Characterization of collateral blood
vessels (dogs)
R01HL19451-03 0004 Functional characteristics of the
left heart - Quantitative coronary arteriography (human)
R01HL19675-02 Coronary pharmacoangiography
** ROlHL-1993702 Vasodilators in experimental myocardial
infarction (dogs)
ROlHL-20226-02 Cardiac bypass and coronary collateral
physiology (dogs)
ROlHL-20253-02 Effects of exercise on the heart and its
blood supply (dogs)
ROlHL-20598-03 The coronary vascular response to
ischemia (dogs, pigs)
ROlHL-20630-03 Development of a pulsed Doppler velocity
detector (human, animals)
R23HL-21298-02 Coronary vasomotion (dogs, pigs)
ROlHL-21872-01 Myocardial perfusion in the hypertrophied
heart (dogs)
ROlHL-22273-01 Oral and lung absorption of nitroglycerin
(rats)
ROlHL-22952-01 Validation of quantitative coronary
arteriography (dogs)
•* ROlHL-23653-01 Protection of the ischemic myocardium
(dogs)
CARDIOVASCULAR AGENTS, VASOPRESSORS
*• POlHL-06835-17 0056 Cardiovascular disease -
Angiotensin analogs-Sarcosine on arterial pressure,
aldosterone (dogs)
POlHL-08682-15 0005 Regulation of the cardiovascular
system - Smooth muscle and mechanical properties of
blood vessels (dogs, human)
POlHL-10342-13 0019 The integrated function of
respiration and circulation - Cerebral circulation and
metabolism (dogs)
ROlHL-1 1802-10 Cardiovascular surgical research (dogs,
sheep, swine, cats, monkeys)
P50HL-14217-08 0061 Specialized center of research in
thrombosis - Pharmacology-Comparison of platelets and
vascular smooth muscle (animal)
R01HL1464405 Optimization diastolic augmentation and
systolic sink (dogs)
ROlHL-14775-08 Mechanisms of drug action in vascular
smooth muscle (dog, rabbits)
88
ROlHL-16292-05 0017 Surgery and non-obstructive
coronary insufficiency - Cardiopulmonary resuscitation
(human)
ROlHL-16511-04 Sympathetic afferent activity of cardiac
origin (dogs, monkeys)
ROlHL-16916-04 0011 The role of albumins in lung water
accumulation - Whole body distribution and exchange of
albumin (rabbits, human, monkeys)
R01HL17355-04 Pulmonary vascular adjustments in
circulatory collapse (dogs, rats)
P50HL17667-04 0031 Study of ischemic heart disease -
Pathophysiology in ischemic heart disease (dog, cat, rabbit,
monkey)
** ROlHL-18096-04 Vasoactive agents in splanchnic viscera
(primates, dogs)
R01HL18979-02 Mechanisms in local regulation of
coronary flow (rabbits)
ROlHL-192 18-03 Local regulation of coronary flow by
prostaglandins (rabbits)
R01HL-20399-03 Vascular control in experimental diabetes
mellitus (dog)
ROlHL-20895-03 0010 Cineangiographic studies of
cardiovascular system ■ Cortical necrosis and acute renal
failure (human, dogs, rats, rabbits)
ROlHL-21308-01 Prostaglandins and local control of the
circulation (rats, dogs)
ROlHL-21877-01 Iso-renins in the hypertensive rat
** R01HL22946-01 Prostaglandins, platelet aggregation and
vasoactivity (human, rats, rabbits)
CARDIOVASCULAR AND PUUWONARY
RESEARCH STUDY SECTION
** R01HL00487-29 Vasomotor tone and venous return
(human, dogs, monkeys )
** ROlHL-03303-21 Factors regulating electrolyte excretion by
the kidney (human, dogs)
** R01HL03941-18 Uterine blood flow and changes in
pregnancy (sheep)
** R01HL04666-19 Artificially paced hearts-Technology,
physiology (human, dogs)
** ROlHL-07047-16 Comparative study of cardiac conduction
system (human, birds, mammals)
** R01HL07605-16 Congenital heart disease research
program (human, dogs)
** ROlHL-07776-15 Sudden death and cardiac arrhythmias
(human, dogs, cats)
** ROlHL-08659-14 Myocardial performance and metabolism
in the newborn (sheep)
** ROlHL-08789-11 Respiratory muscles and ventilatory
control in man (and dogs)
** ROlHL-08977-14 Quantitation of flow and solute flux in
microvessels (cats, rats)
** R01HL097 11-13 Instantaneous blood flow in ascending
aorta (human, dogs)
** ROlHL-10009-13 Regional lung function in man
** ROlHL-10330-11 Physiological mechanics of the heart and
arteries (dogs, rabbits, horses)
** ROlHL-10622-12 Volumes and compliance of pulmonary
circulation (human, dogs)
** R01HL10881-13 Structure and function of
microcirculation (hamsters, rats. cats, dogs)
** ROlHL-10897-12 Effects of hormones on cardiac
electrogenesis (rabbits, guinea pigs, dogs)
** ROlHL-10942-09 Study of genetic hypertension in rats
** ROlHL-10951-11 Neural control of the heart (dogs, rats)
** ROlHL-1128912 Analysis of stress in pulsatile dynamics
** R01HL11717-09 Effect of stenotic obstructions on flow in
arteries (dogs)
** ROlHL-1 1906-11 Comparative study of heart function
(cats. rats, hedgehogs, squirrels)
** ROIHLI 1907-08 Mechanisms of physiological responses
to exercise (human, dogs)
** R01HL12083-11 Flow field in aorta and its major
branches (dogs, phantom models)
** ROlHL-12415-10 Evaluation of left ventricular function
(dogs, rabbits)
** ROlHL-1242110 Pathophysiology of circulatory shock
(dogs, baboons)
** R01HL12486-10 Structure-function correlation in the
atrium (rabbits)
** ROlHL-1249310 Bioengineering analysis of microvascular
function (cats, rabbits)
** ROlHL-12494-10 Continuum mechanics in biophysics
(human, animals)
•* R01HL12530-10 Emphysema-Respiratory function in
disease (human, dogs, rats)
** R01HL12690-09 Systemic and local vascular adjustment
in shock (monkeys, cats)
** ROlHL-12774-08 Ionic coupling in activation of cardiac
muscle (frogs, guinea pigs)
M R01HL12879-09 Pulmonary transport and metabolism in
vivo
** ROlHL-12974-10 Tracer kinetics, flows and masses in
body organs (human, dogs)
** ROlHL-13134-07 Mechanism of chemorecepfor discharge
(cats)
•* ROlHL-13375-09 Cellular potential changes causing
cardiac arrhythmias (dogs)
•* ROlHL-13596-07 Clearance of plasma proteins from
alveoli
** ROlHL-13639-07 Factors altering the course of myocardial
dysfunction (cats)
CAR
" ROlHL-13645-11 Tryptophan-induced pulmonary
emphysema (cattle, goats, rabbits)
* R01HL13654-08 Antilipemic regimes in peripheral
arteriosclerosis (human)
* R01HL13824-06 Defense mechanisms in pathogenesis of
emphysema (human, dogs)
ROlHL-13888-15 Regulation of respiration
* ROlHL-13921-07 The lung as a metabolic organ (animals)
* ROlHL-14456-07 Lung metabolism-Enzymes in the
pulmonaiv circulation (human, animals)
* ROlHL-14545-06 Mechanics of compensatory ventricular
hypertrophy (dogs)
* ROlHL-14614-07 Voltage control of contraction in heart
(sheep)
* ROlHL-14645-07 Blood flow measurement by ultrasonic
catheter tip methods (human, dogs)
* ROlHL-14663-07 Pulmonai> oxygen toxicity in newborn
lung (human, mice)
'* ROlHL-1469206 Alpha 1 antitrypsin deficiency and
pulmonary disease (human)
•* ROlHL-14693-07 Survival value of physiological responses
to hypoxia (dogs)
•* ROlHL-14706-07 Fetal hearts in organ culture (mice)
•* ROlHL-14713-06 Hypothermia and the heart (bats, guinea
pigs)
" ROlHL-14832-06 Myocardial cells -Autonomic and rhythmic
mechanisms (chick embryo, rats)
** ROlHL-1487006 Dynamics of oxygen and carbon dioxide
regulation (animals)
** ROIHL 1489907 Mechanism and prevention of cardiac
arrhythmias (dogs)
** ROIHL 14903-07 A new index of cardiac contractility
(human, dogs, baboons)
** ROlHL-14967-06 Chemorecepfor function in dynamic
ventilatory control (human, dogs)
** ROlHL-15231-05 Mechanisms of hemodynamic changes
during digestion (dogs)
** R01HL15273-06 Metabolism of pulmonary surfactant
(human, rats)
** ROlHL-1531607 Lung surfactant system-Control
mechanisms (rats)
** ROlHL-15416-06 Cardiovascular control in normal and
disease states (dogs, baboons)
** R01HL15526-05 Respiratory mechanics in children
** R01HL-15580-06 Humoral control of pulmonary and
systemic circulation (animals)
** ROlHL-15659-05 Dynamic isolation studies of control of
respiration (human)
** R01HL15677-06 Autonomic nervous system function in
bronchial asthma (human, guinea pig, rabbit)
** ROlHL-15681-06 Coronary flow studies of partially
obstructed vessels (dogs)
** ROlHL-15694-06 Pulmonary factors in circulatory
regulation
** ROlHL-15740-06 In vitro studies on heart cell function
(rats)
** ROlHL-1576405 CAMP dependent protein kinase in
cardiac contraction (dogs)
** ROlHL-15810-06 Electrolyte physiology and respiratory
acid-base (dogs)
" ROIHL 15888-05 Comparative stereology of the
myocardium (birds, mammals)
" ROIHL- 16066-05 Studies on neurogenic control of the
circulation (human, dogs)
** ROlHL-16076-06 Electrophysiology of fibrillation and
defibrillation (human)
** ROlHL-16094-06 The dynamics of microcirculatoiy function
(dogs)
** R01HL16135-05 Mechanisms of cardiac auforhythmicity
(dogs, bats)
** R01HL161 52-06 Electrophysiology of neonatal to adult
heart (cats, frogs, guinea pigs)
•* ROlHL-16236-04 Detailed characteristics of coronary blood
flow (horses, dogs, calves)
** ROlHL-1632503 Breathing patterns in man
" ROlHL-1632806 Membrane electrical properties of
vascular muscle (human, animals)
** ROlHL-16330-06 Aging-tissue injury and repair (rats)
** ROlHL-16419-03 Arterial uptake of lipoprotein-Kinetic
analysis (rabbits)
** ROlHL-16436-04 Role of calcium and thyroxine in heart
function (rats)
** ROlHL-16463-05 Localization of airways obstruction and
responses
R01HL-16674-05 Airborne metals and lung permeability
(bullfrogs, rats)
** ROlHL-16725-03 Physiological regulation of pulmonary
surfactant (dogs, rats)
** ROlHL-16828-04 Gradient and transport of oxygen in
tissue and organs (mammals)
** ROlHL-16901-05 Multipolar linkage between heart
geometry and surface (human, dogs)
M ROlHL-1691604 The role of albumins in lung water
accumulation
** ROlHL-17246-03 Oxygen uptake at one minute of exercise
(human)
** ROlHL-1731404 Effects of anesthesia and loading on
respiration (human, cats)
** ROlHL-1732204 Functional characteristics of smooth
muscle isolated from lung (animals)
** R01HL17355-04 Pulmonary vascular adjustments in
circulatory collapse (dogs, rats)
(contd)
•Excludes iDuline methodotogy OR covers only general proieds which preclude
"Onented significantly to above subject.
indexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
CAR
ROIHl i;376 04 Analysis ot ; binds in heirt by optical
diMiiclion (mammilsl
ROIM11740J03 Metabolic control ol caid(ac output
(dog^)
R01H11/M70J Artttial wall onyten tianspoft in
attiaiosclarosis (labbils. dogs)
ROIHL l/bSl 03 Patent ductus artetiosus and pulmonary
hypertension (dogsl
ROIHI i;!i91 03 Development of electromagnetic
rhooangiogiaphy (human, dogs)
ROIHL 1/689 06 Neurophysiologic studies ol respiratory
control (cats)
ROIHL 17/1903 Lung in|ury. substrate utilization, oxygen
toxicity (rats, rdbbits. dogs)
ROIHL 1//68 04 Development ot collateral ventilation
(dogs, tish, horses)
ROIHL 1///604 Pulmonary mucus transport in
obstructive lung diseases (human)
ROIHL U80004 Pulmonary reflexes Central pathways
(cats, dogs, rabbits)
** ROlHH/808 03 Ettect of altered oxygen aMinity on
oxygen transport (human, rats)
ROIHL 17809 04 Eftects ot exercise on the coronary
vasculature (rat. dog)
ROIHL 1/853 03 Peripheral circulation in heart failure
89
Characteri/ation of collateral blood
(animals)
ROIHL 1/87304
asthma (human)
ROIHL 1/90303
Pathophysiology ot exercise induced
Regional circulatory responses to hypoxia
(rats, cats, rabbits)
ROIHL 1/932 04 Blood flow regulation in muscle (cats)
R01HL1795403 Narcotics and the circulation (human.
dogs. pigs, monkeys)
** ROIHL- 18020-04 Splanchnic hemodynamics in man
R01HL18022-03 Role of multicomponent diffusion in gas
exchange (avian eggs)
ROlHL-18024-03 Regional myocardial flow and function
relationships (dogs)
ROIHL-18070 04 Regulation of intrapulmonary airways
and vessels (human, animals)
*• ROlHL-18080-03 Extrinsic control of intestinal
microcirculation (dogs)
ROlHL-18145 03 Oxygen transport mechanisms in hypoxia
(dogs. rats, rabbits)
ROlHL-18156-02 Hemodynamics in curved arteries
ROIHL 18191-04 Models of hypoxic pulmonary
hypertension (cattle, minipigs)
R01HL-18308-03 Comprehensive studies of mucociliary
transport (dogs)
ROlHL-18328-03 Hemoglobin function and tissue
oxygenation (human, dogs)
'* R01HLI8338-04 Computer feedback study of cardiac
muscle mechanics (rats)
ROlHL-1846703 Fingertip blood flow in normals and
Raynaud's disease (human)
R01HL-1853704 Regional blood flow after acute
myocardial injury (dogs)
ROlHL-18606-04 Pathogenesis and measurement of
pulmonary edema (human, rabbits, dogs)
R0IHL-I8630-03 Pulmonary hemodynamics in atelectasis
and hypoxia (dogs)
R01HL-I8647-03 Ischemic myocardial injury in cultured
heart cells (rats)
R01HL-I8710-02 Non-invasive reflection oximetry in
peripheral tissue (dogs)
ROlHL-18711-03 Electrophysiology of heart cells (rats.
chicks)
R01HL-I8736-03
(rabbits)
R01HL-I8749-03
heart (dogs)
R01HL18866-02
Protein transport through arterial tissue
Ventricular mechanics in the overloaded
Microvascular flow, volume, and
reactivity (rats, cats)
ROlHL-18933-03 Energy output and efficiency of left
ventricle (dog)
ROIHL-18969-02 Arterial wall oxygenation (rabbits, dogs)
ROlHL-18977-03 Non-invasive diagnosis of peripheral
arterial disease (human, dogs)
R01HL-18979-02 Mechanisms in local regulation of
coronary flow (rabbits)
R01HL19010-03 Metabolism and cell biology of lung
surfactant system (rabbits, sheep)
ROlHL-19045-03 Electrophysiology of cardiac automaticity
(human, dogs)
ROlHL-19056-03 Blood triglycerides and lipoprotein lipase
in the lung (rats)
R01HL-I9089-03 Diastolic properties of the left ventricle
(human, dogs)
ROlHL-19135-04 Heterogeneity of regional myocardial
blood flow (dogs)
R01HL-19202-O3 Adenosine, prostaglandins in relation to
coronary flow (guinea pigs)
ROlHL-19216-03 Characterization of cardiac pacemaker
activity (cat, dog. rabbit)
ROlHL-19218-03 Local regulation of coronary flow by
prostaglandins (rabbits)
ROlHL-19225-02 Types and mechanims of pulmonary
hypertension
ROlHL-1925603
control (dogs)
ROlHL-19257.03
stress (dog)
Arterial baroreceptors in cardiovascular
Cardiovascular adjustment to behavioral
ROIHl 1927b 03
vessels (dogsl
ROIHI 19298 03 Pulmonary h«modyniimic\ (dogs. f.its)
ROIMI 19299 03 Myoglobin and oxygen supply to heart
and muscle cells (rats, pigeons)
ROIHI 193S2 03
neonates
ROIHL 19391 03
filling (dogs)
ROIHL 19398 03
arrhythmias (dogs)
ROIHL 19423 03
rats)
ROIHL 19431 03
human lung
ROIHL 19449 03
ROIHL 1946003
Respiratory heal and wuter loss In
Dynamic determinants of left ventricular
Regional conduction abnormalities and
)
Catecholamine action on the heart (cats.
Regional mucociliary transport in the
Gas exchange in acute respiratory failure
Mechanics of tho papillary muscle and
the left ventricle (cats, rabbits)
ROIHL 19461 03 Myocardial energetics in hypertrophy and
heart failure (rabbits)
ROIHL 1948503 Calcium uptake by normal and failed
cardiac ATPase (dogs)
ROIHL 1948603 Dipole moment measurement of cardiac
mass (rabbits, pigs)
ROIHL 19628 03 Mechanisms of pulmonary alveolar
proteinoses (human, rats)
" ROIHL 196/4 02 Electrolyte permeability of single
capillaries (frogs)
ROlHL-196/602 Physico chemical interactions In
pulmonary surfactant
ROlHL-196/8-01 Quantification of intrathoracic fluid by
impedance (human, dogs)
ROIHL 19768 02 Recording and analysis of low levels
cardiac signals (human, dogs)
ROlHL-19827-02 Role of the upper airways in the control
of breathing (human, cats, dogs)
R01HL-19848-02 Contractile activation by rapid
temperature jumps (frogs)
ROlHL-19937-02 Vasodilators in experimental myocardial
infarction (dogs)
R01HL-20087-02 Developmental processes in pulmonary
hypertension (rats)
ROIHL 20122-02 Operational mechanisms of airway
receptors (dogs, pigs)
ROlHL-20184-02 Desensitization of tracheal muscle to
isoproterenol (rats, rabbits)
ROlHL-20192-02
laser scattering
ROlHL-20196-02
muscle
ROIHL-20286-02
Ciliary activity of the lung studied by
Regulation of coronary arterial smooth
Interventions to improve cardiac function
in ischemia (dogs)
ROlHL-20328-01 Noninvasive assessment of autonomic
cardiac control (dogs)
ROlHL-20344-02 Regulation of protein turnover in lung
tissue (rats)
ROlHL-20352-02 Defenses of lung cells against oxygen
toxicity (human, animals)
ROlHL-2035402 Direct determination of oxygen tension in
the clinical environment (human, dogs)
ROlHL-20366-03 Protein turnover and amino acid
transport by lung (rats)
ROlHL-20371-02 Intravascular redistribution of blood
volume (dogs)
ROlHL-20564-02 Pathogenesis of peripheral arterial
disease (rats, rabbits)
ROlHL-20566-02 Lactate metabolism in the lung (rats)
Respiration during prolonged hypercapnia
ROlHL-20568-03
(rats)
R01HL-20574-03
activity (cats)
R01HL-20598-03
ischemia (dogs, pigs)
R01HL-20607-02
(dogs)
ROlHL-20611-02
nucleotides
ROlHL-20612-02
Brain stem integration of chemoreceptor
The coronary vascular response to
igs)
Tissue analysis by mass spectrometer
Airway smooth muscle and cyclic
Chronic animal model of pulmonary
vascular injury (dogs)
ROlHL-2064302 Analysis of heart cell contraction (rats)
Physical factors and coronary flow (dogs)
Sites of leakage in pulmonary edema
RGlHL-20648-01
ROlHL-20652-01
(dogs)
ROlHL-20690-02
Pulmonary hemodynamics in lung edema
during PEEP (dogs)
ROlHL-207 19-02 Cold induced pulmonary hypertension
(cattle)
ROIHL-208 15-02 Validation of indirect tests of small
airways function (human, dogs, ponies)
ROlHL-20847-02 Respiratory neurochemical control
(human, goats)
R23HL-20968-02 Respiratory failure-Control and muscle
dysfunction (human)
ROlHL-20989-01 Pathophysiology of bronchial asthma
(sheep, dogs)
ROlHL-21032-02 Injury, wall thickness, and arterial wall
oxygenation (dogs, rabbits)
ROlHL-21034-01 Compensatory responses to arterial
occlusion (dogs)
R01HL-2103801 Electrically induced cardiac EM-
histochemical changes (animals)
Phospholipid exchange proteins in lung
Right ventricular contraction and
CAR
R23HI 71042 01 Cardiopulmonary relleui and Ihtir
inilomical basis (dogs)
R23H17I050 02 Mechaniims ol raeipaoMon pulmonary
edema (rabbitt)
* ROIHI 21099 02 Subceliulir chinfii of blood vtittlt in
hypertension (rats)
' ROIHI 21140 01 Studies of pulmonay alvfolir
macrophage lunction (rabbits)
ROIHI 2115802 Cardiac receptors with vagal Cliber
affercnis (cats)
R23HI 2111)8 01 Hypoxemic respiratory failure Physiologic
evaluation (human, dogs)
• ROIHL21i;b02
tissue (lambs)
* R23HL 2119/02
relaxation (dogs)
• ROIHL 21209 02 Alterations of metabolism in itchemic
myocardium (swine)
ROIHL 212/801 Abnormal cardiac wall motion viewed
ultrasonically (human, dogs, phantoms)
R23HL 21298 02 Coronary vasomotion (dogs, pigs)
ROIHL 2131402 Respiratory tract secretion of ions, water
and mucus (human, dogs)
ROIHL 21342 02 Isolation and analysis of sodium channel
from heart (frogs)
R23HL 21368 02 Perinatal cardiac electrophysiology (dogs)
ROlHL-21376-02 Blood gas barrier solute and water
transport (rabbits)
R23HL 21393 01 Cardiac adaptation to aging and stress
(rats)
ROIHL 21444-02 Pulmonary mechanics during postnatal
development (human)
ROIHL 21452 02 Pulmonary capillary filtration in
myocardial ishemia (dogs)
' R01HL2148201
diabetes (rats)
ROIHL 2150002
stress (dogs)
ROlHL-2151801 Improvement in regional ventilation-
perfusion resolution (human)
R23HL 21539-02 Mechanical properties of isolated small
bronchioles (rabbits)
R23HL-21559-0I Oxygen supply and blood flow through
aortic vasa vasorum (dogs)
ROlHL-21568-02
(animals)
ROlHL-215/0-01
Cardiac function and metabolism in
Pertormance of respiratory muscles under
energetics (cats)
ROlHL-21657-01
hypoxia (dogs)
ROlHL-21735-01
infarction (cats)
R23HL-21783-01
Cell biology of the alveolar-capillary unit
The mechanical basis of myocardial
Regional nonischemic myocardial
Electrophysiology after healed myocardial
'^Jill!^™^''* '"'*'«^"'o» 0" "wers onty general projects which preclude indexing
Onented signiticartly to above subject.
at the specific level.
M Grant has subprojects describing specific research aspects
See Appendix for investigator's name and grant number.
Ionic control of contractility in anoxic
myocardium (rabbits, rats)
ROlHL-21812-02 Actions of drugs and ions on cardiac
membranes (rabbits, guinea pigs)
R23HL-21842-01 Control of sugar entry in normal and
diabetic heart (rats)
R23HL-21853-01 Lung metabolism and alveolo-capillary
permeability (rats)
ROlHL-21872-01 Myocardial perfusion in the hypertrophied
heart (dogs)
R23HL-21973-01 Catecholamine metabolism and the heart
(human, guinea pigs)
R23HL-220n01 Adrenergic receptor cyclase system in
sensitized lung (rats, guinea pigs)
ROlHL-22022-01 Respiratory muscle dysfunction in
respiratory failure (human)
ROlHL-22077-01 Vasoactive amine disposition in cultured
endothelium (rabbits)
ROlHL-22079-01 Heart receptor sites for digitalis and
steroid hormones (animals)
R01HL-22080-0I Phosphorus NMR studies on cardiac
tissue (rats, rabbits)
ROlHL-22137-02 Structure-function pathology of isolated
heart cells (mice, rats)
ROlHL-2217702 Mechanisms of control of pulmonary
smooth muscle (dogs)
ROlHL-22223-01
models)
ROlHL-2223501
(rabbits)
ROlHL-22313-01
(human)
ROlHL-22333-01
(rats)
ROlHL-22354-01
metabolism (rats)
ROlHL-22415-01 Mechanisms responsible for disease
severity in asthma (human)
ROlHL-22418-01 Neural control of cardio-respiratory
function (cats)
ROlHL-22435-02 Pulmonary alveolar-capillary permeability
characteristic (dogs)
ROlHL-2244601 Chemical and functional studies of low
copper in lung (pigs)
ROlHL-22463-02 Pinocytotic vesicles and pulmonary
edema (rats)
ROlHL-22470-01 Liposome myocardial uptake in infarct
and ischemia (dogs, rats, mice)
ROlHL-2248401 Neural control of cardiac conduction and
excitation (dogs)
(contd)
The cardiopulmonary junction (dogs.
Mechanism of cardiac pacemaking
Lung elastic recoil-Age and disease
Cellular basis of small airways function
Alpha-adrenergic effects on heart
CAR
** ROlHL-22546-02 Baroreceptor reflex mechanisms in man
** ROlHL-22549-02 Transport across alveolar capillary
membrane (dogs)
** ROlHL-22622-01 Sleep apnea and desaturation-
mechanisms and incidence (human)
** ROlHL-22664-01 Regulation of myocardial cell growth
(rats, guinea pigs)
** ROlHL-22715-01 Neural integration of the cardiovascular
reflexes (dogs))
** ROlHL-22723-01 The morphologic basis of airflow
obstruction (human)
** ROlHL-22732-01 Central organization of cardiac afferent
nerves (cats, monkeys)
** ROlHL-22843-01 Pulmonary physiology in liquid ventilation
(lambs)
** ROlHL-22862-01 CNS-mediated effects of antiarrhythmic
drugs (dogs)
** R23HL-22920-01 Dynamic airway behavior (dogs)
** ROlHL-22924-01 The airway mucosal barrier (guinea pigs)
** ROlHL-2301501 Mechanisms of hypo-oncotic pulmonary
edema (human, dogs)
" ROlHL-23604-01 Hepatic microvascular regulatory
mechanisms (rat)
" ROlHL-23624-01 Effect of drugs on ischemic cardiac cells
(dogs, guinea pigs, pigs)
** ROlHL-23626-01 A study of the regulation of myocardial
hypertrophy (rats)
** ROlHL-23653-01 Protection of the ischemic myocardium
(dogs)
** ROlHL-23969-01 Surfactant synthesis by type II cells in
vitro (rats)
** ROlHL-23982-01 Control of coronary flow by carbon
dioxide tension (dogs)
** ROlHL-23985-01 Role of the diaphragm in regional lung
mechanics (dogs)
CARDIOVASCULAR AND RENAL STUDY SECTION
** ROlHL-00340-29 Electrolyte disturbance in cardio-renal
disease (human, dogs, rats)
** ROlHL-00759-29 Regulation of electrolyte and acid base
equilibrium (dogs)
** ROlHL-01015-27 Hypertension and left ventricular
hypertrophy (dogs)
** ROlHL-01486-23 Quantitative study of T-wave mechanisms
(human, rabbits, dogs, chickens)
** ROlHL-02493-22 Kidney function in experimental heart
failure (dogs, rats)
** ROlHL-03290-22 Controls of cardiac and vascular smooth
muscles (cats, rats, dogs)
** ROlHL-05875-18 Pathologic metabolic and physiologic
studies of heart (human, dogs, cats)
** ROlHL-0673618 Biogenicmechanical factors in
microcirculation (rats, gerbils)
** ROlHL-06975-18 Pathogenesis and prevention of
hypertension (rats)
** R01HL0713917 Cardiodynamics and metabolism of
congestive failure (human, dogs)
** ROlHL-08508-15 Cardiac conductivity and automaticity
(human, dogs, rabbits)
** ROlHL-09154-14 Central control of distribution of organ
blood flow (monkeys)
♦* R01HI.-09234-13 Amino acids of contractile proteins of
failing hearts (dogs, hamsters)
** ROlHL-0956214 Cardiac protein synthesis, overload,
alcohol and anoxia (guinea pigs)
** ROlHL-0983112 Effect of resistivity variations on
electrocardiogram (human)
** ROlHL-09911-12 Hormonal and dietary modification of
NaCl toxicity (rats) mice)
** ROlHL-09914-13 The myocardium in diabetes mellitus
(dogs, monkeys)
** ROlHL-10384-13 Blood flow and nucleotide metabolism
(animals)
** R01HL10417-I2 Multiple systems in electrocardiography
(human)
M ROlHL-10612-13 Humoral factors in heart failure and
hypertension
** ROIHLI 1046-12 Renin, angiotensin, steroids, ions and
blood pressure (human, sheep, rabbits)
** R01HL1115212 Vascular physiology (human, cats, dogs)
** ROlHL-l 1876-11 Regional myocardial blood flow and
metabolism (dogs, swine)
** ROlHL-12307-08 Non-surgical treatment of congenital
heart disease (human, dogs)
** ROlHL-12607-10 Dynamics of pulsatile blood flow (human,
dogs, rats)
** ROlHL-1261110 Basic and clinical studies of the ST-T
deflection (human, dogs)
*• ROIHL- 126 14-09 Microcirculatory control mechanisms and
hypertension (bats, rats)
** ROlHL-12684-09 Angiotensin I and converting enzyme in
hypertension (human, primates, dogs)
** ROIHL- 12766-09 Structure-function relation of blood
vessels (rats, monkeys)
** ROlHL-12775-08 Cerebral microcirculation (mice)
** ROlHL-12997-07 Myocardial defects induced by potassium
depletion (human, rats, cats)
** ROlHL-13036-08 Coronary thrombosis -Effects on
myocardium and in vivo detection (dogs, monkeys)
** ROlHL-13323-08 Intrarenal pressure and renal function
(human, dogs)
** ROlHL-13427-09 Neural control of blood volume (monkeys,
dogs)
90
ROlHL-13437-09 Physical and mechanical parameters in
the microcirculation (animals)
ROlHL-13454-08 Behavioral stress and cardiomyopathy
(monkeys, cats)
R01HL-13595-08 Renin and vascular hyper-reactivity in
hypertension (human, rats)
ROlHL-13623-08 Atrial receptors (dogs)
ROlHL-13634-08 Renal hypertension in pregnancy (sheep)
ROlHL-13870-09 Control of myocardial sarcotubular
calcium stores (dogs)
ROlHL-13917-20 Secretion and effects of adrenal
hormones (human, rabbits, sheep)
ROlHL-13936-06 Microvascular responses in hypertension
(human, rats)
ROlHL-14092-07 Homeostatic regulation of plasma choline
(rats, dogs, chickens)
ROlHL-14306-07 Quantification of arterial pressure control
(dogs)
' ROlHL-14461-08 Cardiac metabolism in heart failure
(rats)
' ROlHL-14526-07 Oral contraceptives and hypertension
(rats)
' ROlHL-14529-07 Systems analysis of baroreflex (dogs)
■ ROlHL-14560-07 Hypertension produced by sympathetic
dysfunction (human, rats)
' ROlHL-14646-05 Pathophysiology of myocardial ischemia
(dogs, rats)
* ROlHL-14688-05 Myocardial assessment by inverse
electrocardiography (monkey)
' ROlHL-147 17-06 Hemodynamics and heart structure-
Ventricular overload (dogs)
* ROlHL-149 13-06 Hypertension-Genetic influence of kidney
(rats)
* ROlHL-14944-07 Renal vascular reactivity in hypertensive
patient
* ROlHL-150 16-07 New concepts in cardiac ultrasound
technology (human)
* ROlHL-15124-05 Genesis of hypertension in renal disease
(human, dogs)
* ROlHL-15190-07 Physiological basis of arrhythmias and
their therapy (human)
* ROlHL-15270-06 Local mechanical properties of the aortic
tissue (dogs, pigs)
* ROlHL-15307-06 Central nervous control of renin and
blood pressure (dogs)
* ROlHL-15430-05 Cardiopulmonary adaptation of newborns
to altitude (human)
* ROlHL-15444-06 Neonatal development of adrenergic
receptor mechanisms (pigs)
* ROlHL-15498-06 Effects of physical training on heart
(rats)
* ROlHL-15512-06 Drug treatment of stenosing primate
atherosclerosis (rabbits, monkeys)
* ROlHL-15522-06 Influence of mannitol on ischemia
cardiac muscle (dogs, cats, rats)
'* ROlHL-15528-05 Renin kinetics in hypertensive and
uremic plasma (human, dogs)
'* ROlHL-15562-05 Regulation of skeletal muscle blood flow
(dogs)
'* ROlHL-15607-06 Physiological control of splanchnic
circulation (dogs)
•* ROlHL-15722-06 Hemorrheology studies related to in vivo
blood flow (human)
■* ROlHL-15758-06 Catecholamine release in the heart
(dogs)
•* ROlHL-15808-06 Role of angiotensinogen in hypertension
and stroke (human, rabbits)
** ROlHL-15837-06 Renin and cardiac hypertrophy in
hypertension (rats)
** ROlHL-15839-05 Physiological role of isorenin and
kallikrein (animals)
** ROIHL- 158 52-06 Vascular ion transport and hypertensive
mechanisms
** ROlHL-15983-04 Regional myocardial blood flow (dogs)
** ROlHL-16052-05 Cardiac glycosides-Mechanism of
inotropic action (dogs)
** ROlHL-16206-04 Regression of atherosclerotic plaques
(monkeys, dogs)
** ROlHL-162 19-05 Mechanisms of atherogenesis in chronic
uremia (human, rats)
** R01HL-16233-05 Molecular cardiology of MDP-induced left
ventricular failure (dogs)
** ROlHL-16240-05 The cardiac histamine receptor (rabbits,
guinea pigs)
** ROlHL-163 15-05 Analysis of interaction between CNS
vasomotor systems (cats, rats)
** ROlHL-164 12-04 Release of nucleosides from the ischemic
heart (human, dogs)
** ROlHL-16454-03 Vascular muscle reactivity in
hypertension (human, rats)
** ROlHL-16489-04 Renal prostaglandins -Synthesis and
function (human, dogs, rats)
** ROlHL-16496-04 Prostaglandins and renin experimental
hypertension (rabbits)
** ROlHL-16511-04 Sympathetic afferent activity of cardiac
origin (dogs, monkeys)
** ROlHL-16567-04 Differentiation of the heart-cell
membrane (mice, chick)
** ROlHL-16587-04 Cholesterol binding saponins and
atherosclerosis (monkeys)
** ROlHL-16603-05 Human and experimental renal diseases
(animals)
CAR
'* ROlHL-16643-02 Fluorocarbon emulsions as artificial
blood (animals)
" ROlHL-16648-16 Integrated control of cardiovascular
activity (cats)
" ROlHL-1665606 Left ventricular function in exercise
(dogs)
** ROlHL-16657-06 Innervation of coronary arteries and heart
(rats)
** ROlHL-16658-05 Intrarenal regulation of sodium
reabsorption
** ROlHL-16706-04 Excitation-contraction coupling and heart
failure (dogs, rabbits)
** R01HL-ie710-03 Myocardial subcellular localization of
calcium (dogs)
** ROlHL-16760-05 Dynamic control of coronary blood flow
(dogs)
** ROlHL-16768-04 The sympathetic nervous system and the
arterial wall (rabbits, pigeons)
** ROlHL-16918-05 Role of steroids in hypertension (human)
** ROIHL- 17243-05 Cause of chronic experimental renal
hypertension (dogs, rabbits)
** ROlHL-17335-05 Contractile properties of hypertensive
arterioles (rats)
** ROlHL-17364-04 'Big renin'-Biochemical and clinical
studies (human)
•* ROlHL-17366-05 Mechanisms in the production of renal
hypertension (rabbits, dogs)
** ROlHL-17408-03 Fresh blood rheology-Relation to
cardiovascular risk (human)
** ROlHL-17458-04 Renal control of sodium excretion (rats)
" R01HL-17459-03 Myocardial ischemia (dogs)
** ROlHL-17516-04 Role of androgen as a risk factor in
atherogenesis (human, animals)
** ROlHL-17532-04 Infarct size-ECG, angio, path, correlation
in dogs
** ROlHL-17555-05 Distribution and metabolism of labeled
digitaloids (dogs, guinea pigs)
** ROlHL-17592-03 Activation and contraction heat in
enlarged hearts (rabbits)
** ROlHL-17628-03 Pulsatile pressure-flow dynamics (dogs)
** ROlHL-17629-03 Developmental aspects of cardiovascular
function (human, cats, rabbits)
** ROlHL-17631-05 Experimental congestive heart failure and
hypertrophy (cats)
" ROlHL-17705-04 Kallikreinkinin system in hypertension
(human, rats, dogs)
** ROlHL-17711-05 Mechanism of hypoxic regulation of lung
circulation (rats. cats, guinea pigs)
** ROlHL-17721-04 Effect of sex hormones on vascular
connective tissue (rats)
** R01HL-17724-03 Oral contraceptives and hypertension
(rats)
** ROlHL-17736-04 Metabolic change during cardiac
ischemia (rats, dogs)
** ROlHL-17749-03 Adrenocortical factors in human
hypertension (human)
** ROlHL-17754-03 Pathogenesis and prevention of
hypertension sequelae (rats)
** ROlHL-17781-03 Hypertension, kidney disease and renal
lymph (dogs, rats)
** ROlHL-17799-02 The presence and significance of heart
acetylcholine (cats)
** ROlHL-17865-04 Studies on aging-Effects of sex
hormones (rats, dogs)
** ROlHL-17895-04 Myocardial function and metabolism
following ischemia (rats)
** R01HL-17902-04 Mammalian renal microcirculation
(hamsters)
** ROlHL-17907-04 Brain regulation of cardiac arrhythmia
(pigs. cats, rats)
** ROlHL-17909-04 Drug treatment of vascular scleroprotein
defects (human, turkeys)
** ROlHL-17931-04 Normalized body surface potential maps
(children)
" ROlHL-17947-04 Experimental renal and neurogenic
hypertension (human, animals)
** ROlHL-18010-04 Capillary transport of large molecules
(dogs, sheep)
" ROlHL-18019-04 The endocrine kidney in hypertension
(mice)
** ROlHL-18027-03 New vasoactive factors and their role in
hypertension (human, dogs, rats)
** ROlHL-18032-03 Development of normal and myopathic
mammalian heart (hamsters)
** ROlHL-18050-04 Mechanisms of cardiovascular
teratogenesis (chick embryo) k embryo)
** ROlHL-18050-04 Exercise and coronary atherosclerotic
heart disease (monkeys)
** ROlHL-18087-03 Development and regression of cardiac
hypertrophy (rats, rabbits)
** ROlHL-18102-02 Role of the adrenal cortex in human
hypertension
" ROlHL-18190-03 Myocardial blood flow in acute
myocardial infarction (human, dogs)
** ROlHL-18204-03 Regional blood flow in viral myocarditis
(turkeys)
** ROlHL-18280-03 Regulation of cardiac contractility and
metabolism (rats)
** ROlHL-18398-04 Mechanisms of delayed and asymetric
ventricular conduction (human, dogs)
*• ROlHL-18426-04 Regulation of renal hemodynamics (dogs)
(contd)
tjcMa nutiiM methodotogy OR cowers only general projects which preclude Indexing at the specific level.
"Oiitiittd significantly to above subject.
M Grant has subprajects describing specific research aspects.
See Appendix for investigators name and grant number.
CAR
•' ROIHl 1846803 Th« dijiributlon of How In the
myocaidium (do|u pig)
ROIHI 18492 03 Matsutement o( regionil coronary flow
lastrve (human, dogs)
" R01Hll8bl7 03 Inlrlnjic innarvatlon ot the heart (dogs)
R0imi8t)38 03 Th« rola of electrotonus in His PuiKinje
function (dog)
ROlHL 185/903 Vasoactive hormones and blood pressurg
regulation (dogs. rats, rabbits)
ROIHI 1861003 Early intervention ol age related arterial
changes (pigeon)
ROIHL 18624 03 Study o( klninj in hypertension and other
diseases (human)
ROIHL 1862904 Inlluence ot aging and hypertension on
the myocardium (rats)
ROIHL 1869203 Glycasaminoglycins and lipoproteins ot
human plasma
R01HL1871804
reactivity (dogs)
ROIHL 1873003
Prostaglandin precursors and vascular
Role o( mineralocorlicoids In low renin
hypertension (human, rats)
ROIHL 18831 03 Microscopy of spontaneously hypertensive
arterial lesion (rats)
ROIHL 1884504 Regulation of renal circulation and salt
excretion (rats, dogs)
ROIHL 1884803 Etiology and development of congenital
heart disease (dogs, cats)
ROIHL 18862C2 Thirst and its contribution to edema
(dogs)
R01HL1887503 Angiotension, prostaglandins, pressure
and the kidney (rats)
ROIHL 1888202 Hormones in hypertension (human)
" R01HL1889102 Electrolyte intake and blood pressure in
hypertension (human)
ROlHL-18893-03 Mechanism of angiotensin action-Role of
receptor (rats)
R01HL18912-03
(cats, dogs)
ROlHL-18932-03
Mechanics of heart muscle contraction
Brain microcirculation observed in vivo
after trauma (mice)
ROIHL- 1900903 Morphometric analysis of the sinoatrial
node (ferret)
R01HL1901203 Smooth muscle of resistance vessels in
hypertension (rats)
' R01HL19027-03 Calcium and cyclic AMP in causation of
hypeilenslon (rats)
ROIHL 19039-03 Circulation studies by one vs two circuit
model (dogs)
ROIHL- 19048-03 Structure of baroreceptors in
hypertension (rats)
ROlHL-19057-03 Catecholamines and cyclic AMP in
cardiovascular system (rats, dogs)
R01HL-19076-03 Vagal control of heart rate-A biophysical
model (rabbits)
ROlHL-19091-02
(dogs)
ROlHL-19112-03
ROlHL-19133-03
Sustained increase in cardiac output
Atherosclerosis studies (monkeys)
Contractile and elastic properties ot
cardiac muscle (cats)
R01HL-19134-04 Angiotensin, prostaglandins, adrenergic
interactions (rats, rabbits)
ROlHL-19139-03 Dispersion of diffusible indicators in the
body (human, cats, dogs)
R01HL-I9144-03 Contraceptive steroids and experimental
hypertension (rats)
*• ROlHL-19209-03 Role of ADH in experimental renal
hypertension (dogs, rats)
ROlHL-19226-03 Vascular smooth muscle in hypertension
(rats)
ROlHL-19229-02 Prostaglandins and hypertension (human
rats. dogs, rabbits)
ROIHL- 19246-03 Regression of cardiac hypertrophy-
Myocardial and renal (human)
R01HL-1925I-03 An index of sympathetic activity In
hypertension (rats)
ROlHL-19255-03 Evaluation of diagnostic clinical
hemorrheology (human)
ROlHL-19279-03 Intracellular action of aldosterone in
hypertension (human, rats)
ROlHL-19287-03 The antihypertensive function of the
renal medulla (human, rats, rabbits)
ROlHL-19343-03 Behavioral influences on cardiac
contractility (monkeys)
ROlHL-19370-03 Coronary capillary exchange-The effects
of ischemia (dogs, sheep)
ROlHL-19374-03 Pharmacology of kinins in cardiovascular
disease (rats, rabbits)
ROlHL-19425-03 Cardiac function in hypertrophy (dog)
Role of angiotensin sensitivity in renin
M
Functional characteristics of the left
ROlHL-19428-03
release (human)
R01HL-I9451-03
heart
R01HL-I9454-02 Rheological factors in transport across
arterial wall (dogs)
R01HL-I9467-03 Regulation of blood pressure (rats, dogs)
Cardiac actions of digitalis (dogs, cats)
Myocardial protein degradation (dogs.
ROlHL-19487-03
ROlHL-19648-03
rabbits)
ROlHL-19677-03
ROlHL-19825-02
hypertension (dogs)
Venous structure and function (dogs)
Renin-volume interactions in coarctation
91
ROllll 19830 02 Shear to aortic histamine syntheiii and
permeability (dogs)
ROIHL 1997/02 Genesis of circulatory shock by
pancreatic peptides (cats, dogs)
ROIHL 1999/ 02 Prostaglandin precursors and Inleslinil
vasculature (cats, rabbits)
ROIHL 20054 02 Cultured blood vessel cells
Pathophysiology (human, animals)
ROIHL 201 // 02 Effects ol erythrocyte deformabllily on
tissue perfusion (rats)
ROIHL 20183 02 Portacaval shunt as treatment lor
hyperlipemia (pigs)
ROIHL 2019002 Pathogenesis of cardiac hypertrophy
(dogs)
ROIHL 20201 01
receptors (rats)
ROIHL 20206 02 Carbohydrates-nucleotides and adrenergic
interactions (rabbits, cats, rats)
ROIHI 202 11 02 Role ol taurine in the heart (dogs, rats.
Hypertension and vascular steroid
Prospective bundle branch block study
Cardiac fiber direction and the QRS
Hemodynamic relations to metabolism in
mice)
** R01HL2023802
(human)
** R01HL20273-02
complex (dogs)
ROlHL-20283-02 Maintenance of cellular integrity in
ischemic hearts (cats)
ROIHL 20542-03 Regional hemodynamics in spontaneous
hypertension (rats)
ROlHL-20563-02 Restoring microcirculation after platelet
aggregation
** ROlHL-20572-02
hypertension
ROlHL-20594-02 Renal enzymes that regulate blood
pressure (human, rats)
ROlHL-20597 02 Electrophysiologic correlates of
myocardial ischemia (human, dogs, rabbits)
R01HL-206C4-03 Sympathectomy Cardiovascular and
molecular pharmacology (animals)
ROlHL-206 10-02 Nerve growth factor and obstructive
cardiomyopathy (dogs)
R01HL-20630-03 Development of a pulsed Doppler velocity
detector (human, animals)
R01HL-2064501 Etiology of myocardial infaction (human)
R01HL-20685-02 Pituitary-adrenergic-ovarian vasomotor
interaction (dogs)
R01HL-20749-01 Developing heart-Biophysical aspects
(sheep)
ROlHL-20768-02 Mechanisms of circulatory regulation in
heart failure (guinea pigs)
ROlHL-20782-01 Coronary flow regulation by adenosine
(rats, dogs)
ROlHL-20827-02 Effects of hypertrophy on the coronary
circulation (dogs)
ROlHL-20864-01 Postnatal maturation of cardiovascular
regulatory system (minipig)
R01HL-20883-02 Fiber geometry in hypertrophy and
cardiomyopathy (human)
ROlHL-2092402 Atherosclerosis and arterial cell functions
(human, rabbits)
R01HL-21030-01 Calcium regulation and hypertension
(rats)
R23HL-21066-02 Angiotensin and prostaglandin control of
aldosterone (rats)
ROlHL-2109202 Factors other than renin in renal
hypertension (rats)
R0IHL-21094-01 Arterial baroreceptors and renal function
(dogs)
R01HL-21103-01 Parametric mechanical studies of
hypertensive arteries (dogs, rats)
R01HL-21112-02 Aldosterone binding, clearance, and
secretion in man
R01HL-21145-02 Response of atria to hyperosmolality-
Mechanisms (rabbits)
R23HL-21167-02 The electrophysiology of cardiac
hypertrophy (rats)
ROlHL-21182-02 Active tension and shortening in cardiac
hypertrophy (rabbits)
ROlHL-21187-01 Potassium, norepinephrine, and coronary
arterial tone (dogs)
R23HL-21234-02 The regulation of cardiac hypertrophy
(rabbits)
' ROlHL-21260-02 Risk factor relationships of
atherosclerosis (monkeys)
R23HL-21262-02 Sodium-calcium interactions in
mammalian myocardium (rabbits, cats)
ROlHL-2 12 72-02 Sodium homeostasis and renal
prostaglandins (dogs)
R01HL-21274-01 Prorenin -Physiological and biochemical
analysis (human)
R01HL-21283-02 Simulation studies of the ECG in acute
ischemia (and human)
R23HL-21291-02 Renin-mineralocorticoid axis in
hypertensive diabetics (human)
R23HL-21292-01 Human ventricular activation-Patterns
and mechanisms (human)
R01HL-21308-01 Prostaglandins and local control of the
circulation (rats, dogs)
R23HL-21325-02 Sarcomere kinematics in cardiac
contraction (rats, rabbits)
R23HL-21332-02 Pulsatile regulation of flow in the
microcirculation (cats)
Mechanical interactions between ventricle
Contractility in cardiac failure (hamsteri)
Pathophysiology ol edema (rals. cats)
Hemodynamic effects of dietary sodium
CAR
ROIHI ? I I'll 0? Renal end vatculir control by
tyrnpalhnlic ganglia (animali)
R23HI 21382 02 llfpcl of pretiure on renal blood flow
and lunilion (dogi)
ROIHI 2141802 fiperimenlal myocardial infarction (rati)
ROIHI 21425 02 Servo simulated compliance changet A
reversible Ml (dogi)
ROIHI 21435 02 Control, cardlovatculir and renal effectt
of potassium (dogs)
ROIHL 21436 02 Autonomic control ol renal function
(cats)
R23HL 21462 02
arteries (dogs)
ROIHL 21493 02
ROIHL 21498 02
R01HL2152301
in man
RCIHL 2152502 Effect of cations, anions and water upon
blood vessels (dogs, rats)
ROIHL 21574 01 Automaticity of AV node and its adjacent
tissues (dogs)
ROIHL 21654 01 Autonomic determinants of arrhythmia
due to ischemia (cats)
ROIHL 21673 01 Pathophysiology of venous changes in
hypertension (rats, rabbits, human, dogs)
R01HL2177901 Steroids in adrenal regeneration
hypertension (rats)
ROIHL 21820-01 Regulatory role of myosin in cardiac
hypertrophy (dogs)
ROIHL 21843 01 Ischemia, diabetes and the
microcirculation (rats. cats, hamsters)
R01HL-2185001 Calcium transport in the hypertrophied
myocardium (rats, animals)
ROlHL-21851-01 Cerebral microcirculation in experimental
hypertension (cats, rabbits)
ROlHL-21877 01 Iso-renins in the hypertensive rat
Blood volume distribution in hypertension
Hypertension, microvascular control and
Studies of vasomotor control (rats)
Adrenal steroids in adolescent and adult
R01HL2189301
(human)
R23HL-21901-01
exercise (rats)
R23HL-21914-01
R23HL-21917 01
hypertension
ROlHL-2199301 Hypertensive hypertrophy-Effects of
cardiac mechanics (rats)
R23HL 2200401 Imaging and ECG studies in acute and
chronic IHO (human)
ROlHL-22008-01 Left ventrivular calcium content and
contractility (rats)
ROlHL-22040-01 Regulation of lysyl-crosslinking in
vascular tissue (rats, turkeys)
ROlHL-22 172-01 Hypotension, renal ischemia and effect of
mannitol (dogs, rats)
ROlHL-22216-02 Vascular mechanisms in renal
hypertension (dogs)
R01HL-22225-01 Hormonal regulation of blood pressure
and blood flow (human, animals)
R23HL-22245-02 Functional characteristics of atrial
receptors (rats)
R0IHL-22261-O1 Compliance of fluid spaces in advancing
hypertension (rats)
ROlHL-22281-01 Microprobe analysis and metabolite
levels of ischemic mycardium (dogs)
ROlHL-22296-01 Autonomic mechanisms in man
R01HL-22306-0I Renal catecholamines- Pathophysiology
of hypertension (dogs)
ROlHL-22390-01 Effect of chloride on renin (rats, dogs)
R01HL-224I1-01 Neuroendocrine involvement in
hypertension (rats)
R23HL-22438-01 The etiology of genetic hypertension
(rats)
ROlHL-22482-01
excretion (dogs)
ROlHL-22506-01
hypertensions
ROlHL-22527-01
Circulatory hemodynamics and sodium
Hemodynamics of the clinical
^Exdudo routirw methodokigy OR covers only general projects which preclude indexing
Onertod signrficaiitly to above subject.
atthespecificlevel.
M Gram has subprojects describing specific research aspects
See Appendix for investigators name and grant number.
Prostacyclin-thromboxanes in the
cardiovascular system (human, rabbits)
ROlHL-22563-02 Prostaglandins, the kidney and
hypertension (rats)
ROlHL-22594-01 Reflex control of the circulation in heart
failure (dogs)
ROIHL 22603-01 Trace metals, vascular activity and
hypertension (rats)
ROlHL-226 17-01 Angiotensin, hypertension and the CNS
(sheep)
ROlHL-22623-01 Polyamines cellular mediators of
atherogenesis (human)
ROIHL-22641-01 Ventilation, perfusion, and systemic
arterial reflexes (dogs)
ROlHL-22667-01 Mechanisms of baroreceptor adaptation
in hypertension (dogs)
R23HL-22669-01 Cardiovascular effects from visceral
afferents (dogs)
R23HL-22728-01 Neural control of renin secretion (dogs)
ROlHL-22738-01 Role of bioelectric potentials in platelet
adherence (bats. rats, hamsters)
R23HL-22745-01 Vascular mechanics and structure in
hypertension (miniature swine)
ROlHL-22750-01 Digoxin in heart failure with sinus
rhythm (human)
ROlHL-22813-01 Palmitylcamitlne inhibition of ion pumps
in ischemia (dogs)
(contd)
CAR
Systematic study of bronctiial circulation
Effect of carbon dioxide on local gas
ROlHL-22828-01 Adenosine and catecholamine interaction
in ttie tieart (rats)
ROlHL-22836-01 The spontaneously hypertensive kidney
(rats)
ROlHL-22910-01 Control of breathing pattern in health
and disease (human, animals)
ROlHL-22911-01 Mechanism of clearance of lung edema
fluid (dogs)
ROlHL-22917-01 Microvascular pressures in the intact
beating heart (rabbits)
ROlHL-22928-01
(sheep)
R23HL-22932-01
exchange (dogs)
R23HL-22933-01 Transvascular fluid and protein exchange
in the lung (sheep)
ROlHL-22939-01 Human kinin and fibrinolytic systems
and renal disease (human)
ROlHL-22946-01 Prostaglandins, platelet aggregation and
vasoactivity (human, rats, rabbits)
' ROlHL-22952-01 Validation of quantitative coronary
arteriography (dogs)
' R23HL-22959-01 Heart development in inherited
cardiomyopathy (hamsters)
' R23HL-22972-01 Microcirculatory function in hypotension
(rats, hamsters)
■ R23HL-22975-01 Dynamics of autoregulation of muscle
blood flow (dogs)
' ROlHL-2297601 Nonuniform ventilation and diffusing
capacity (human)
' ROlHL-22977-01 Role of vasoconstrictor mechanisms in
heart failure (human, dogs)
* ROlHL-22990-01 Angiotensin II receptors -Mechanisms of
regulation (rats)
* ROlHL-23025-01
adults (rats)
* ROlHL-23312-01 Hemodynamics and vasoactivity in renal
hypertension (human, dogs)
* ROlHL-23599-01 Mechanisms of ischemic rhythm
disorders (dogs)
* ROlHL-23600-01
dogs, rats)
* ROlHL-23602-01
Adaptive heart growth in neonates and
Ions, water, and hypertension (human.
Physiology of renin, aldosterone and
prostaglandin (human, rats, dogs)
** ROlHL-23900-01 Mechanical measurement of cell
membrane viscosity (human)
CARDIOVASCULAR DEFECTS CONGENITAL
SEE CONGENITAL ABNORMALITIES. CARDIOVASCULAR
DEFECTS
CARDIOVASCULAR DISEASE EDUCATION
SEE EDUCATION, HEALTH EDUCATION, CARDIOVASCULAR
DISEASE EDUCATION
CARDIOVASCULAR DISORDERS (GENERAL)
SEE ALSO BLOOD COAGULATION DISORDERS, INTRAVASCULAR
COAGUUTION DISSEMINATED
SEE ALSO BLOOD COAGUUTION DISORDERS, VON
WILLEBRAND'S DISEASE
SEE ALSO CARBOHYDRATES METABOLISM DISORDERS,
DIABETIC ANGIOPATHIES
SEE ALSO CEREBROVASCULAR DISORDERS
SEE ALSO CONGENITAL ABNORMALITIES, CARDIOVASCULAR
DEFECTS
SEE ALSO EDUCATION, HEALTH EDUCATION,
CARDIOVASCULAR DISEASE EDUCATION
SEE ALSO EYE CIRCULATORY DISORDERS
SEE ALSO GASTROINTESTINAL CIRCULATORY DISORDERS
SEE ALSO HEART DISORDERS
SEE ALSO KIDNEY-CIRCULATORY DISORDERS
SEE ALSO LIVER CIRCULATORY DISORDERS
SEE ALSO NEOPLASMS OF CARDIOVASCULAR SYSTEM
SEE ALSO PREGNANCY CIRCUUTORY DISORDERS
SEE ALSO RESPIRATORY CIRCULATORY DISORDERS
ROlHL-01755-25 Fetal and neonatal cardiovascular
function (sheep)
** ROlHL-02942-22 Biochemistry of cardiovascular connective
tissue (human, cattle, primates)
ROlHL-03341-22
Co Georgia
ROlHL-04697-17
(human)
Functional pathology of cardiovascular
Epidemiology of atherosclerosis in Evans
International heart disease epidemiology
Cardiovascular-respiratory physiology and
** ROlHL-05694-20
disease (human)
M POlHL-06285-18
biochemistry
M POlHL-06296-18 Cardiovascular and pulmonary
adaptation to stress
M POlHL-06314-17 Immunologic mechanisms in
cardiovascular disease
POlHL-06314-17 0057
cardiovascular disease
(human)
POlHL-06314-17 0060
cardiovascular disease
Immunologic mechanisms in
- Antigens in cardiovascular disease
Immunologic mechanisms in
Strept antigens and infections in
cardiovascular complications (human, animals)
POlHL-06314-17 0061 Immunologic mechanisms in
cardiovascular disease - Role of viruses in cardiovascular
and renal disease (human, mice)
P01HL-06835-17 Cardiovascular disease
POlHL-08805-15 Regulation of ventilation and pulmonary
circulation
92
POlHL-08805-15 0049 Regulation of ventilation and
pulmonary circulation ■ Pulmonary hypertension produced
by Dirofilaria immitis in the dog
R01HL10182-13 Circulatory function and electrolytic
metabolism (dogs, human)
POlHL-10436-13 0014 A multidisciplinary study of
congenital heart disease - Cardiovascular pharmacology
(dog)
P01HL-11310-12 Mechanisms of cardiovascular disease
R01HL11551-11 RNA and protein synthesis in repair of
heart injury (mice, rats)
POlHL-11678-11 0017 Cardiovascular dynamics and their
control - Overall control of circulation-Mathematical
analyses
ROIHLI 1907-08 Mechanisms of physiological responses
to exercise (human, dogs)
POlHL-12373-10 0020 Cardiopulmonary physiology and
pathophysiology ■ Hospitalization and patient care
ROlHL-127 11-09 Mathematical approach to cardiovascular
mechanics (human, animals)
ROlHL-13172-10 Post-trauma lung mechanics and fluid
exchange (human, dogs, monkeys)
R01HL13629-08 Hemorrhagic diseases (human)
POlHL-1438807 Regulation of the circulation in
pathological states
POlHL-14388-07 0179 Regulation of the circulation in
pathological states ■ Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
POlHL-14388-07 0183 Regulation of the circulation in
pathological slates ■ Vasopressin in cardiovascular
regulation (dogs, rats)
POlHL-1438807 0190 Regulation of the circulation in
pathological states - Mechanisms of the renal actions of
aldosterone (rats)
R01HL14692-06 Alpha 1 antitrypsin deficiency and
pulmonary disease (human)
* ROlHL-15191-07 Multiparameter methods for
cardiovascular research
ROlHL-1533506 The nature of the collagen-platelet
interaction (animals)
* R01HL15416-06 Cardiovascular control in normal and
disease states (dogs, baboons)
1 P01HL15835-06 Study of muscles related to heart
disease
ROlHL-15991-05 Evaluation of heart stimulants in sea
anemones
POlHL-161 17-05 0007 Ion movements and membranes in
cardiovascular control - Physiological and molecular
properties of ionophores (dogs, rabbits)
ROlHL-16236-04 Detailed characteristics of coronary blood
flow (horses, dogs, calves)
R01HL16325-03 Breathing patterns in man
■* P01HL164 11-04 0002 Blood systems in coagulation and
vessel disease - Early stages of coagulation and
cardiovascular disease (human, rabbits)
POlHL-1641104 0004 Blood systems in coagulation and
vessel disease - Platelets reactions in vascular injury
(human, animals)
ROlHL-1645403 Vascular muscle reactivity in
hypertension (human, rats)
ROlHL-15582-05 Artificial lungs (dogs)
R01HL16634-13 Regulation of metabolism in fibroblasts
and platelets (human, rabbits, sheep)
ROlHL-16637-04 Development and regression of cardiac
hypertrophy (rats)
** R01HL17408-03 Fresh blood rheology-Relation to
cardiovascular risk (human)
ROlHL-17479-04 Blood storage-The production of
cardiotoxic material (dogs, human, swine)
** R01HL17516-04 Role of androgen as a risk factor in
atherogenesis (human, animals)
** ROlHL-17591-03 Development of electromagnetic
rheoangiography (human, dogs)
** R01HL-17721-04 Effect of sex hormones on vascular
connective tissue (rats)
R01HL-17909-04 Drug treatment of vascular scleroprotein
defects (human, turkeys)
ROlHL-180 19-04 The endocrine kidney in hypertension
(mice)
** R01HL-19030-03 Tissue protection during circulatory
interruption (dogs)
•* ROlHL-19374-03 Pharmacology of kinins in cardiovascular
disease (rats, rabbits)
** R01HL-20384-09 Social stimulation, RNA and
cardiovascular disease (animals)
** ROlHL-2053502 Cardiovascular disease and evolving
diabetes mellitus (human)
ROlHL-20630-03 Development of a pulsed Doppler velocity
detector (human, animals)
** ROlHL-206 78-02 Cardiovascular adaptation to stress in
disease states (dogs)
** R01HL-21145-02 Response of atria to hyperosmolality-
Mechanisms (rabbits)
" ROlHL-21764-01 Ultramicroanalysis of prostaglandins and
related compounds (rats)
** ROlHL-22255-01 The etiology/prevalence of peripheral
arterial disease (human)
R23HL-2262101 Blood cell-mediated pulmonary (human)
** POlHL-2263301 0003 Cellular and molecular biology of
lipoprotein metabolism - Sterol metabolism in platelets and
megakaryocytes (human, rabbits, guinea pigs)
CAR
R01HL-22740-01 Behavior and cardiovascular disease-
Basic mechanisms (human)
ROlHL-23 194-02 Genetics of hypertension and associated
variables (human)
R01HL-23603-01
disease (rats)
NOlHV-32931-09
center
NOlHV-53010-03
Morphogenesis of hypertensive vascular
Establishment of a lipid research clinic
NAS-NRC tv*in registry
CARDIOVASCULAR DISORDERS, ANEURYSM
SEE ALSO CARDIOVASCULAR DISORDERS. AORTIC ANEURYSM
SEE ALSO CARDIOVASCULAR DISORDERS, ARTERIOVENOUS
SHUNTS ABNORMAL
SEE ALSO CARDIOVASCULAR DISORDERS. VASODILATATION
SEE ALSO CEREBROVASCULAR DISORDERS. CEREBRAL
ANEURYSM
SEE ALSO HEART DISORDERS, ANEURYSMS
R01HL09622 14 Pathogenesis of atherosclerosis (rats)
Pathophysiology of myocardial ischemia
R01HL14546-05
(dogs, rats)
ROlHL-1465105
(dogs, rats)
ROlHL-21851-01
Mechanical behavior of left ventricle
Cerebral microcirculation in experimental
hypertension (cats, rabbits)
ROlHL-22506-01 Hemodynamics of the clinical
hypertensions
CARDIOVASCULAR DISORDERS, AORTA
DISORDERS (GENERAL)
ROlHL-l 1897-11 Pathogenesis of experimental
atherosclerosis (rabbits, guinea pigs)
** R01HL-17909-04 Drug treatment of vascular scleroprotein
defects (human, turkeys)
** R01HL18050-04 Mechanisms of cardiovascular
teratogenesis (chick embryo) k embryo)
ROlHL-1847304
(human, mules)
ROlHL-19109-03
Genesis of atherosclerotic lesions
Regression of chronic atherosclerosis
1
(rabbits)
** ROlHL-20114-02 Collagen-platelet interaction and human
aorta collagen (human)
** ROlHL-2089503 0009 Cineangiographic studies of
cardiovascular system - Aortic changes in atheromatosis
(rabbits)
CARDIOVASCULAR DISORDERS, AORTA
OBSTRUCTIONS
ROlHL-13426-09 Left ventricular bypass for myocardial
infarction (cattle, human)
ROlHL-2244501 Platelet inhibitors-Effect on coronary
bypass grafts (dogs)
CARDIOVASCULAR DISORDERS, AORTA
OBSTRUCTIONS, AORTA COARCTATION
** ROlHL-03181-21 0028 Hemodynamics as applied to
surgical problems - Extra-renal factors in the hypertension
of coarctation (dog)
ROlHL-0692416 Humoral and metabolic aspects of
cardiac function (mammals, non-human, human)
POlHL-10436-13 0008 A multidisciplinary study of
congenital heart disease - Physiologic consequences of
chronic hypoxemia (human)
POlHL-13262-07 0011 Arterial wall in atherosclerosis •
Role of hypertension in atherosclerosis (human, monkey,
dog)
R01HL13595-08 Renin and vascular hyper-reactivity in
hypertension (human, rats)
** P50HL15062-07 0020 Study of lipoproteins, artery wall,
and atherosclerosis ■ Artery wall reactions-Elevated
pressure and hyperlipemia (monkey)
R01HL18527-03 Subcellular response of heart to
functional overload (hamsters, rats)
ROlHL-19425-03 Cardiac function in hypertrophy (dog)
" ROlHL-19825-02 Renin-volume interactions in coarctation
hypertension (dogs)
** R01HL-21071-02 Mechanisms of hypertension in
coarctation of the aorta (dog)
ROlHL-2143802 Structure and permeability of arterial
endothelium (pigs)
ROlHL-23205-01 Repetitive exercise and cardiac
enlargement (dogs)
** ROlHL-23600-01 Ions, water, and hypertension (human,
dogs, rats)
ROlHL-23603-01 Morphogenesis of hypertensive vascular
disease (rats)
CARDIOVASCULAR DISORDERS, AORTIC
ANEURYSM
** R01HL-17909-04 Drug treatment of vascular scleroprotein
defects (human, turkeys)
" R01HL-18050-04 Mechanisms of cardiovascular
teratogenesis (chick embryo) k embryo)
CARDIOVASCULAR DISORDERS, ARTERIAL
OCCLUSIONS
SEE ALSO CARDIOVASCUUR DISORDERS. AORTA
OBSTRUCTIONS
SEE ALSO CARDIOVASCULAR DISORDERS, AORTIC ANEURYSM
SEE ALSO CARDIOVASCULAR DISORDERS. ARTERIOSCLEROSIS
SEE ALSO CARDIOVASCUUR DISORDERS. EMBOLISM
SEE ALSO CARDIOVASCUUR DISORDERS. INFARCTION
SEE ALSO CARDIOVASCUUR DISORDERS. ISCHEMIA
(contd)
"Excludes routine melliodotogy OR covers only general projects which preclude
"Oriented significantly to above subtect.
indexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigators name and grant number.
CAI
SEE Also CARDIOVASCULAR DISORDERS. RAYNAUD'S
DISEASE AND PHENOMENON
SEE ALSO CARDIOVASCULAR SlIRGfRY VASCULAR
OCCLUSION IHLRAPIIIIIC
SEE ALSO CEREBROVASCULAR DISORDERS, CEREBRAL
OCCLUSIONS AND THROMBOSIS
SEE Also CEREBROVASCULAR DISORDERS.
CEREBROARIERIAL OCCLUSIONS EXTRACRANIAL
SEE ALSO HEART DISORDERS. CORONARY OCCLUSIONS AND
THROMBOSIS
SEE ALSO KIDNEY CIRCULATORY DISORDERS. RENAL ARTERY
OBSTRUCTION
SEE ALSO RESPIRATORY CIRCUUTORY DISORDERS.
PULMONARY CIRCULATORY OBSTRUCTIONS
R01HL00487 29 Vasomotor tone and venous return
(human, dogs, monkeys )
POIHI 06285 18 0147 Cardiovascular respiratory
physiology and biochemistry Metabolic regulation ot
cerebral microcirculation (cats)
•• POIHL 07293 17 0054 Noninvasive cardiovascular
measurements ■ Detection ol arterial occlusive disease
(human)
POIHL 07293 17 0057 Noninvasive cardiovascular
measurements Peripheral vascular scanner engineering
evaluation and error analysis (human)
P01HL07293 17 0058 Non invasive cardiovascular
measurements ■ Peripheral duplex scanner physiologic
evaluation
ROIHL 1282708 Regulation of sodium excretion (dogs.
rats)
P50HL 1506207 0020 Study of lipoproteins, artery wall,
and atherosclerosis ■ Artery wall reactions-Elevated
pressure and hyperlipemia (monkey)
POIHL 1691005 0001 Regulation of the peripheral
circulation • Quantitative studies of microcirculatory control
(bats)
** R01HL1695205 Cardiovascular pathology (rats, rabbits)
POIHL 1742105 0004 Regulation and exchange in the
microcirculation Localization of flow regulation in the
microcirculation (cats, human)
" P50HL 17648-04 0013 Study of ischemic heart disease •
Fate of bypassed and bypassing vessels (dogs)
ROlHL-18977-03 Non-invasive diagnosis of peripheral
arterial disease (human, dogs)
** R01HL19275-03 Characterization of collateral blood
vessels (dogs)
R01HL-I940603 Grading of atherosclerosis by CW doppler
ultrasound (human, dogs)
ROlHL-2033702 Thromboembolic diseases (human)
ROlHL-20381-03 Long-term study of diabetic vascular
disease (human)
ROlHL-20522-03 Peripheral arterial disease in the diabetic
(human)
** R01HL-2I034-01
occlusion (dogs)
ROlHL-2 1548-01
thromboembolic disease (human, mammals)
CARDIOVASCULAR DISORDERS, ARTERIAL
STENOSIS
** R01HL-03181-21 0025 Hemodynamics as applied to
surgical problems ■ Vascular stenosis (dogs)
ROlHL-1 1289-12 Analysis of stress in pulsatile dynamics
** ROlHL-11717-09 Effect of stenotic obstructions on flow in
arteries (dogs)
P01HL-13330-08 0059 Mechanical circulatory support -
Physiologic evaluation of circulatory assistance (cattle)
P60HL-17269-04 0023 National heart and blood vessel
research and demonstration center • Cardiovascular
pharmacology-Ischemia, shock and heart failure (dog cat
rat)
R01HL-I7517-03 Arterial wall oxygen transport in
atherosclerosis (rabbits, dogs)
** P50HL-1 7669-04 0008 Ischemic heart disease center
(SCOR) ■ Segmental ventricular dysfunction during stress-
induced ischemia (dog. human)
P50HL1 7682-04 0005 Study of ischemic heart disease ■
Regional myocardial perfusion deficits and segmental
contraction disorders in man
R01HL18156-02 Hemodynamics in curved arteries
R01HL18468-03 The distribution of flow in the
myocardium (dog. pig)
ROlHL-18492-03 Measurement of regional coronary flow
reserve (human, dogs)
R0IHLI8805-04 0007 Sudden cardiac death and the
onset of myocardial infarction - Analysis of pathologic
factors involved in sudden death (human)
ROlHL-18977-03 Non-invasive diagnosis of peripheral
arterial disease (human, dogs)
R01HL19003-03 High precision densitometry of coronary
angiograms
R01HL-1940603 Grading of atherosclerosis by CW doppler
ultrasound (human, dogs)
R01HL19675-02 Coronary pharmacoangiography
ROlHL-1993702 Vasodilators in experimental myocardial
infarction (dogs)
R01HL-206 78-02 Cardiovascular adaptation to stress in
disease states (dogs)
ROlHl-21751-02 0002 Thallium and antimyosin in
ischemia and infarction ■ Canine models of ischemia and
infarction
ROlHL-21 796-01 Applied pulsatile hemodynamics in
vascular surgery (dogs)
Compensatory responses to arterial
Pathogenesis of pulmonary
93
ROIHL 22893 01 Evaluating artarlal dllllM by velocity
wave analysis (dogs, human)
•* R0IH1229S2 0I Validation ol quantitative coronary
arloiiography (dogs)
CARDIOVASCULAR DISORDERS,
ARTERIOSCLEROSIS
M ROIHL 01803 23 Artoriosclorosis. glomerulonephritis,
rheumatic lever
ROIHL 019/9 22 Arteriosclerosis in zoo animals on
controlled diets (animals)
M POIHL 06835 17 Cardiovascular disease
ROIHL 07835 17 Experimental hypertension and renal
circulation (rats, rabbits)
POIHL 08805 15 0049 Regulation ot ventilation and
pulmonary circulation Pulmonary hypertension produced
by Dirofilaria immitis in the dog
ROIHL 10894 12 Intestinal bacteria and steroid
metabolism (human, guinea pigs, rabbits, rats)
POIHL 11310 12 0106 Mechanisms of cardiovascular
disease Biochemical characterization ol the collagens in
vascular tissue (catte)
ROIHL 12711 09 Mathematical approach to cardiovascular
mechanics (human, animals)
ROIHL 13256 08 Amino acid transport by red cell
membranes (pigeons)
** POIHL 13262 07 0024 Arterial wall in atherosclerosis
Serial ocular changes in arteriosclerosis and hypertension
ROIHL 13654-08 Antilipemic regimes in peripheral
arteriosclerosis (human)
POIHL 13737-07 0038 Assisted circulation -
Distinguishing the ischemic ventricle from scarred ventricle
by balloon pumping
M P50HL 14164 07 A/S SCOR -Comparative and experimental
atherosclerosis
** P50HL 14164 07 0044 A/S SCOR -Comparative and
experimental atherosclerosis ■ Cell biology-atherosclerosis
project (pigeons)
M P50HL1423605 Prevention of premature arteriosclerosis
M P50HL-1423707 Support for arteriosclerosis center
R01HL1504706 Digital computer analysis of the
electrocardiogram (human)
R01HL1561404 Heredity and oxygen-Eftects on health of
heart-lungs (South America)
ROlHL-15979-05 Elastase. serum inhibitors and the
vasculature (human, swine)
** POlHL-16387-04 0009 The blood vessel and
thrombogenesis - Role of pituitary gland in the
pathogenesis of arteriosclerotic lesions (rats)
ROlHL-1651204 Lipoprotein metabolism and hormonal
regulation (chickens)
** R01HL16904-03 Regulation of smooth muscle cells in
arteriosclerosis (rabbit aorta)
ROlHL-16952-05 Cardiovascular pathology (rats, rabbits)
P50HL-17665-04 0028 Study of ischemic heart disease -
Pathologic and biochemical studies of ischemic
myocardium (human, dog)
P50HL-1 7669-04 0013 Ischemic heart disease center
(SCOR) - Exercise in patients with ischemic heart disease
ROlHL-1 7706-04 Psychosocial hypertension.
catecholamines and drugs (mice)
R01HL17754-03 Pathogenesis and prevention of
hypertension sequelae (rats)
ROlHL-17818-05 Metabolism of cholesterol and cholesterol
in man (also rats, monkeys)
ROlHL-187 14-04 Cardiovascular matrix -Morphogenesis
and maturation (human, chick embryo, mammal)
ROlHL-190 73-02 Heart disease and drinking water at
home
R01HL19255-03 Evaluation of diagnostic clinical
hemorrheology (human)
** ROlHL-1938103 Pathogenesis of viral induced
atherosclerosis (human, chicken)
ROlHL-19839-09 Factors in youth predisposing to chronic
diseases (former college students)
ROlHL-201 79-02 Epidemiology of sudden cardiac death
among women
ROlHL-20787-02 Thromboxanes and prostaglandins-
Biochemical pharmacology (rabbits, human)
ROlHL-214 18-02 Experimental myocardial infarction (rats)
ROlHL-22208-02 Elastin structure, fibrogenesis and
disease (chickens, rabbits)
ROlHL-225 70-01 Interactions of sterols in biological
systems (human)
R01HL-22604-01 Non-invasive system for arteriosclerosis
studies (human)
" POlHL-226 19-01 0012 Cellular mechanisms of heart
failure - Apolipoproteins in hypertriglyceridemia (human)
CARDIOVASCULAR DISORDERS,
ARTERIOSCLEROSIS, ATHEROSCLEROSIS
NOlHI-32926-10 Analysis of lipoproteins (animals)
R01HL-00487-29 Vasomotor tone and venous return
(human, dogs, monkeys )
ROlHL-01803-23 0005 Arteriosclerosis, glomerulonephritis,
rheumatic fever ■ Immunologic and dietary synergy in the
pathogenesis of atherosclerosis (rabbits)
ROlHL-01803-23 0010 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Atherosclerosis Induction-Graft rejection
and hypercholesterolemia (rabbits)
ROlHL-01803-23 0011 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Immunopathologic consequences of
cigarette smoking (human, rabbits, plants)
CAR
' ROIHI 0180)23 0014 Arliirioultrotii. |lomerulonephrilit
rheumatic lever Negeneialed endolhelium on lipid
accumulation in arterial wall (rebbil)
ROIHL 01803 23 0015 Arlerioiilerotii. glomerukinaphrilit.
rheumatic lever Immunologic endothelial injury and lipid
diet atheroscleroM) (rabbits, monkey)
' ROIHL 01803 23 0020 Arteriotcleroiit. glomerulonephrrlit.
rheumatic lever Virus induced arterotclerosit (chickeni)
ROIHL 01803 23 0021 Arterioulerosis. glomerulonephritii.
rheumatic lever Induction ol IgE antibodiet to antigen
from tobacco and iigaretli; -.moke (rabbits)
ROIHL 02033 23 Regulation ol cholesterol eslert in blood
and tissues (rat. tattle, human)
ROIHL 02942 '17 Biochemistry ol cardiovascular connective
tissue (human, cattle, primates)
POIHL 03174 23 Mechanismi of acule vascular reaction
to injury
P01HL03174 23 0001 Mechanisms ol acute vascular
reaction to injury Response of the vascular intima to
injury (human, rats)
POIHL 03174 23 0006 Mechanisms of acute vascular
reaction to injury Atherosclerotic plaque studies using
mosaic analysis (human)
P01HLO3174 23 0010 Mechanisms of acute vascular
reaction to injury Search for mutagens in the human
blood (bacteria, animals)
P01HL03174 23 001 1 Mechanisms of acute vascular
reaction to injury Mutagen metabolism by artery wall in
etiology of atherosclerosis (human, animals)
P01HL03174-23 0012 Mechanisms of acute vascular
reaction to injury < Human atherosclerotic plaque in organ
culture
POlHL-03174 23 0013 Mechanisms of acute vascular
reaction to injury Surface morphology of the aorta in
normal and injured states (rats, rabbits)
R01HL03299-21
(rats, rabbits)
ROlHL-03341-22
Co Georgia
R01HL0342918
Dietary effects on cholesterol metabolism
Epidemiology of atherosclerosis in Evans
•Exdudes routine methodotogy OR covers only general projects which preclude indexing at the specific level
Onorted significantly to above subject.
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigators name and grant number.
Central nervous system and coronary
heart disease (human)
' ROlHL-03734-18 Metabolism of arterial tissue in
atherosclerosis (rabbits)
POIHL-04664-18 0007 Cardiovascular and lung dynamics
- Development and application of ultrasound imaging
techniques
R01HL05062-18 Lipid metabolism in cultured cells
(human, rats, rabbits)
ROIHL-0520918 Lipid metabolism (monkeys)
P01HL0628518 0205 Cardiovascular-respiratory
physiology and biochemistry - Assimilation of cholesterol in
chylomicrons and VLDL (rabbits)
POlHL-0630818 0038 Mechanisms and therapy of
circulatory disease - Electrophysiology of ventricuair
arrhythmias associated with ischemia (dogs)
POlHL-06312-17 0021 Surgical cardiology ■ Cardiac
transplantation-Effect of immunosuppression on
atherogenesis (monkeys)
POlHL-06312-17 0023 Surgical cardiology - Eftect of
denervation on atherosclerosis
POlHL-06314-17 0047 Immunologic mechanisms in
cardiovascular disease - Role of intravascular coagulation
(human, animals)
POlHL-06835-17 0014 Cardiovascular disease - Dietary
induction of severe atherosclerosis and its prevention
(dogs)
POlHL-06835-17 0015 Cardiovascular disease • Plasma
cholesterol esterification in canine atherosclerosis
POlHL-0683517 0016 Cardiovascular disease - Metabolic
interactions to polyunsaturated fatty acids m atherogenic
diet (dogs)
POlHL-06835-17 0017 Cardiovascular disease - Studies
on obese hypertensive rats
POlHL-06835 17 0020 Cardiovascular disease ■ Lipid
metabolism (rats)
POlHL-06835-17 0021 Cardiovascular disease ■ Animal
study in atherosclerosis (dog. guinea pig)
POlHL-06835-17 0026 Cardiovascular disease -
Lipoproteins (human, guinea pig)
POlHL-06835-17 0027 Cardiovascular disease • Studies
in thrombosis-cross-linking of fibrinogen (human)
POlHL-06835-17 0062 Cardiovascular disease - Role of
collagen in atherosclerosis (dogs, pigeons)
POlHL-06835-17 0063 Cardiovascular disease - Studies
on prostaglandins (human, rabbits)
POlHL-06835-17 0064 Cardiovascular disease - Studies
in atherosclerosis (human, animals)
P01HL-07293-17 0054 Noninvasive cardiovascular
measurements • Detection of arterial occlusive disease
(human)
R01HL08506-15 Lipemia-carbohydrate and glyceride
metabolism (human, rats)
R01HL0865914 Myocardial performance and metabolism
in the newborn (sheep)
POlHL-0897414 Natural and experimental atherosclerosis
POlHL-08974-14 0005 Natural and experimental
atherosclerosis ■ Atherosclerosis, coronary heart disease
and sudden death (human)
POlHL-08974-14 0024 Natural and experimental
atherosclerosis - Atherosclerosis, sterol and lipoprotein
metabolism in nonhuman primates
(contd)
CAR
** POlHL-08974-14 0028 Natural and experimental
atherosclerosis Geographic pathology of atherosclerosis
and coronary heart disease (human)
*• P01HL-08974-U 9001 Natural and experimental
atherosclerosis - Core-Lipid chemistry laboratory
** POlHL-08974-14 9002 Natural and experimental
atherosclerosis - Core-Histology and histochemistry
laboratory
** ROlHL-0962214 Pathogenesis of atherosclerosis (rats)
** ROlHL-09744-14 Experimental vascular sclerosis
(monkeys, rabbits)
** R01HL09914-13 The myocardium in diabetes mellitus
(dogs, monkeys)
** R01HL10160-13 Origins of atherosclerosis (human)
** ROlHL-10933-13 Fat metabolism and atherosclerosis
(rabbits, cattle, human, rats)
R01HL10940-13 Lipid transport (rabbits, cattle, chickens)
** ROlHL-1 1289-12 Analysis of stress in pulsatile dynamics
POlHL-1 1310-12 0101 Mechanisms of cardiovascular
disease - Molecular pathogenesis of vascular disease
M PDlHL-11414-11 Thrombosis and atherosclerosis program
** POlHL-11414-11 0037 Thrombosis and atherosclerosis
program - Vascular intimal injury and healing (rabbits,
rats)
ROlHL-1 17 17-09 Effect of stenotic obstructions on flow in
arteries (dogs)
** ROlHL-11775-11 Platelet mechanisms in disease (human,
primates)
ROlHL-1 1880-10 Physiology and pathology of blood
platelets (human, dogs)
•* ROlHL-11897-11 Pathogenesis of experimental
atherosclerosis (rabbits, guinea pigs)
M ROlHL-11901-12 Effects of metabolic surgery on the
hyperlipidemias
ROlHL-1 1901-12 0001 Effects of metabolic surgery on
the hyperlipidemias - Partial ileal bypass (human)
** ROlHL-11901-12 0012 Effects of metabolic surgery on
the hyperlipidemias - Ileal bypass-Animal atherosclerosis
implications (pigeons, dogs, rabbits)
ROlHL-1 1901-12 0013 Effects of metabolic surgery on
the hyperlipidemias - Human cholesterol and bile acids
dynamics-lleal bypass
** ROlHL-12083-11 Flow field in aorta and its major
branches (dogs, phantom models)
ROlHL-12494-10 Continuum mechanics in biophysics
(human, animals)
ROlHL-12740-10 Hypocholesterolemic agents-
Stereochemistry (rats)
ROlHL-12766-09 Structure-function relation of blood
vessels (rats, monkeys)
ROlHL-12869-09 Arterial metabolism, diabetes and
atherogenesis (rats, rabbits)
ROlHL-13036-08 Coronary thrombosis-Effects on
myocardium and in vivo detection (dogs, monkeys)
POlHL-13108-09 0003 Clinical heart transplantation -
Endomyocardial biopsy pathology
POlHL-13108-09 0011 Clinical heart transplantation -
Humoral and cellular kinetics of allograft rejection (human)
** POlHL-13108-09 0014 Clinical heart transplantation -
Platelets and coagulation in accelerated graft coronary
atherosclerosis
ROlHL-13257-09 Inhalation anesthesia on myocardial
metabolism (dogs, swine, human)
M POlHL-13262-07 Arterial wall in atherosclerosis
•* POlHL-13262-07 0011 Arterial wall in atherosclerosis -
Role of hypertension in atherosclerosis (human, monkey,
dog)
** POlHL-13262-07 0012 Arterial wall in atherosclerosis -
Characterization of connective tissue components (animals)
** POlHL-13262-07 0015 Arterial wall in atherosclerosis -
Crosslinkage biosynthesis in aortic elastin and collagen
(animals)
** POlHL-13262-07 0016 Arterial wall in atherosclerosis -
Lipids in elastin preparations from atherosclerotic plaques
(human, animals)
" POlHL-13262-07 0018 Arterial wall in atherosclerosis -
Vasoactive factors of human plasma
P01HL13262-07 0022 Arterial wall in atherosclerosis -
Mechanisms of platelet prostaglanoin formation
POlHL-13262-07 0023 Arterial wall in atherosclerosis -
Isolation and characterization of soluble elastin
POlHL-13262-07 0024 Arterial wall in atherosclerosis -
Serial ocular changes in arteriosclerosis and hypertension
ROlHL-13408-05 Environmental-genetic interactions in
hypertension (rats)
ROlHL-13694-08 Capillaiy basement membrane in
cardiovascular disease (human, rats)
*• ROlHL-13722-08 Acid and alkaline lipases in aortas (rats,
rabbits, human)
** ROlHL-141 11-07 Cholesteryl esters in membranes and
atherosclerosis (human, swine)
ROlHL-14126-17 Effect of function on grafts and implants
of collagen (dogs, monkeys)
M P50HL-14138-05 Center for research on atherosclerosis
** P50HL-14138-05 0008 Center for research on
atherosclerosis - Core lipid laboratory (human)
** P50HL-14138-05 0009 Center for research on
atherosclerosis - Core angiographic-diagnostic laboratory
(human, dogs, birds)
" P50HL-U138-05 0010 Center for research on
atherosclerosis - Diet and exercise as therapy in men with
premature atherosclerosis
94
* P50HL-14 138-05 0014 Center for research on
atherosclerosis - Core biostatisfics laboratory
' P50HL-14138-05 0015 Center for research on
atherosclerosis - Arterial wall-Intermediary metabolism,
enzyme activity and bioenergetics
* P50HL-14138-05 0016 Center for research on
atherosclerosis - Computer analysis of angiograms
P50HL-14141-05 SCOR for atherosclerosis in childhood
* P50HL-14141-05 0001 SCOR for atherosclerosis in
childhood - Clinical implications (infants and children)
* P50HL-14141-05 0002 SCOR for atherosclerosis in
childhood - Intrauterine environment of proband group
(human)
* P50HL-14141-05 0003 SCOR for atherosclerosis in
childhood - Detection of abnormalities in lipid metabolism
(human, rabbits, rats)
P50HL-14141-05 0007 SCOR for atherosclerosis in
childhood Relation of lipid valves to sexual maturation at
puberty (human)
* P50HL-141 47-08 0012 Specialized center of research in
thrombosis - Tissue culture study of arterial cells (human,
hamster)
* ROlHL-14148-07 0009 The regional circulations -
Myocardial circulation in hypertension and atherosclerosis
(human)
'* P50HL-14 164-07 0025 A/S SCOR -Comparative and
experimental atherosclerosis - Animal care resource and
laboratory animal medicine unit (monkeys, pigeons)
•* P50HL-14 164-07 0026 A/S SCOR-Comparative and
experimental atherosclerosis - Comparative pathology unit
(pigeons, monkeys)
•• P50HL-14164-07 0027 A/S SCOR-Coraparative and
experimental atherosclerosis - Hyper- and
hyporesponsiveness to dietary cholesterol (squirrel monkey)
** P50HL-14 164-07 0028 A/S SCOR-Comparative and
experimental atherosclerosis - Hyper- and
hyporesponsiveness to dietary cholesterol (African green
monkey)
** P50HL-14164-07 0029 A/S SCOR-Comparative and
experimental atherosclerosis - Development of pigeon
substrains
** P50HL-141 64-07 0030 A/S SCOR-Comparative and
experimental atherosclerosis - Morphology, angiochemistry-
Oiet induced lesions in African green monkey
** P50HL-14164-07 0031 A/S SCOR-Comparative and
experimental atherosclerosis - Changes in endothelial
permeability associated with atherosclerosis (pigeon)
** P50HL- 14 164-07 0032 A/S SCOR-Comparative and
experimental atherosclerosis - Plasma cholesterol, lesion
regression and vascular function (Rhesus monkey)
** P50HL-14164-07 0033 A/S SCOR-Comparative and
experimental atherosclerosis - Comparative studies of
lipoprotein distribution and metabolism (monkeys)
** P50HL-141 64-07 0034 A/S SCOR-Comparative and
experimental atherosclerosis - Core lipid analytic laboratory
** P50HL-141 64-07 0035 A/S SCOR-Comparative and
experimental atherosclerosis - Lipid metabolism-Interaction
with arterial metabolism (monkey, pigeon)
** P50HL-14164-07 0036 A/S SCOR-Comparative and
experimental atherosclerosis - Connective tissue
metabolism -Interaction with arterial metabolism (monkeys)
P50HL-141 64-07 0037 A/S SCOR-Comparative and
experimental atherosclerosis - Genetic control of plasma
cholesterol-Interaction of dietary fatty acid (monkey)
** P50HL-14164-07 0038 A/S SCOR-Comparative and
experimental atherosclerosis - Peripheral vascular studies-
Cholesterol, lesion regression, vascular function
** P50HL-14164-07 0041 A/S SCOR-Comparative and
experimental atherosclerosis - Nonhuman primate pediatric
atherosclerosis risk factor
P50HL-141 92-08 0002 Specialized center of research in
hypertension - Hypertensive patients with renal artery
stenosis
M P50HL-14197-07 Support for center of research on
arteriosclerosis
P50HL-14197-07 0005 Support for center of research on
arteriosclerosis - Lipoprotein biosynthesis and degradation
in vivo and in vitro (human, animal)
P50HL-14197-07 0006 Support for center of research on
arteriosclerosis - Diets and drugs affecting lipid
metabolism (human)
P50HL-141 97-07 0007 Support for center of research on
arteriosclerosis Metabolic defects in familial
hyperlipoproteinemias (human)
P50HL-14197-07 0008 Support for center of research on
arteriosclerosis - Core facility-Lipoprotein preparation,
immunochemistry
M P50HL-14230-07 A/S SCOR -Lipids, atherosclerosis and
thrombosis
P50HL-14230-07 0092 A/S SCOR-Lipids. atherosclerosis
and thrombosis - Tissue lipids-Cell culture studies
(human)
** P50HL-14230-07 0094 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Studies of atherosclerosis and regression
(monkeys)
** P50HL-14230-07 0099 A/S SCOR-Lipids. atherosclerosis
and thrombosis - Morphological, cytochemical study of
normal and altered vasculature (mice)
P50HL-14236-05 0001 Prevention of premature
arteriosclerosis - Metabolism and transport of cholesterol
and vitamin A (human, rats)
CAR
** P50HL-14236-05 0002 Prevention of premature
arteriosclerosis - Myocardial blood flow in patients with
coronary artherosclerosis
P50HL-14237-07 0002 Support for arteriosclerosis center
- Interactions of lipoprotein particles with vascular surface
(human, rat)
P50HL-14237-07 0005 Support for arteriosclerosis center
- Genetic determinants of apolipoprotein variability in
lipoproteins (human)
ROlHL-14378-07 Lipemias and reconstructive cardiac
surgery (human)
** POlHL-14388-07 0165 Regulation of the circulation in
pathological states - Vascular resistance in experimental
atherosclerosis in Rhesus monkeys
POlHL-14388-07 0166 Regulation of the circulation in
pathological states - Elastic changes in abdominal aorta
with atherosclerosis (Rhesus monkeys)
** POlHL-14388-07 0233 Regulation of the circulation in
pathological states - Pressure-flow relationships after
regression of experimental atherosclerosis
ROlHL-14785-07 Ultrasonic scattering for tissue
characterization (dogs, cattle, human)
** ROIHL- 14826-05 External isotope assay of atherosclerosis
(rats, rabbits)
M P50HL 15062-07 Study of lipoproteins, artery wall, and
atherosclerosis
P50HL-15062-07 0001 Study of lipoproteins, artery wall,
and atherosclerosis - Structure and molecular interactions
of serum lipoproteins (human, monkey)
P50HL-15062-07 0012 Study of lipoproteins, artery wall,
and atherosclerosis Lipoprotein stimulation of arterial
smooth muscle cell proliferation (mammals)
P50HL-15062-07 0013 Study of lipoproteins, artery wall,
and atherosclerosis - Radioimmunoassay of apolipoproteins
(human, monkeys)
** P50HL-15062-07 0018 Study of lipoproteins, artery wall,
and atherosclerosis - Reversal of atherosclerosis in
monkeys
P50HL-15062-07 0019 Study of lipoproteins, artery wall,
and atherosclerosis Factors regulating lipoprotein-smooth
muscle cell interaction (monkey)
** P50HL-15062-07 0020 Study of lipoproteins, artery wall,
and atherosclerosis - Artery wall reactions-Elevated
pressure and hyperlipemia (monkey)
** P5OHL-15062-07 0021 Study of lipoproteins, artery wall,
and atherosclerosis - Core laboratories
M P50HL-15103-07 A/S SCOR-Early natural history of
arteriosclerosis
** P50HL-15103-07 0001 A/S SCOR-Early natural history of
arteriosclerosis - Clinical research -Bogalusa heart study
(children)
** P50HL-15103-07 0013 A/S SCOR-Early natural history of
arteriosclerosis - Experimental models of atherosclerosis
(monkeys)
** P50HL-15103-07 0014 A/S SCOR-Early natural history of
arteriosclerosis - Biochemistry of atherosclerotic lesions
(monkeys, human, cattle)
** ROlHL-15174-06 CV disease epidemiology-Second
generation studies (human)
M POlHL-15265-05 Program on surgical control of the
hyperlipidemias
** POlHL-15265-05 0003 Program on surgical control of the
hyperlipidemias - Central lipid laboratory
" POlHL-15265-05 0011 Program on surgical control of the
hyperlipidemias - Central electrocardiography laboratory
(human)
** POlHL-15265-05 0012 Program on surgical control of the
hyperlipidemias - Central arteriography-Radiography
laboratory (human)
** POlHL-15265-05 0013 Program on surgical control of the
hyperlipidemias - Clinical center - Minnesota
** POlHL-15265-05 0014 Program on surgical control of the
hyperlipidemias - Arkansas clinical center
** ROlHL-15270-06 Local mechanical properties of the aortic
tissue (dogs, pigs)
** ROlHL-1 5448-05 Surgical and metabolic aspects of
venous grafts, (dogs, monkeys, rabbits)
** ROlHL-15478-05 Lipid flux and collagen synthesis in
atherosclerosis (rabbits)
** ROlHL-15504-05 Animal model for studies on averting
atherosclerosis (swine)
** ROlHL-15512-06 Drug treatment of stenosing primate
atherosclerosis (rabbits, monkeys)
** ROlHL-15646-03 Lipid studies in vascular smooth muscle
cells (human, monkeys)
ROIHL- 15648-06 Lipid metabolism-Transport by lateral
diffusion (human, rabbit, cattle)
** ROlHL-15681-06 Coronary flow studies of partially
obstructed vessels (dogs)
ROlHL-15696-06 Mechanism and role of cyclic GMP In
heart (animals)
** ROlHL-15797-05 Lipid metabolism and atherosclerosis in
primates (monkeys, human, squirrels)
POlHL-15835-06 0019 Study of muscles related to heart
disease - Vascular smooth muscle-Electron microscopy,
excitation contraction (animal)
POlHL-15835-06 0025 Study of muscles related to heart
disease - Cellular biology of vascular smooth muscle
(guinea pig)
** ROlHL-15949-05 Lipoprotein metabolism in relation to
atherosclerosis (human, baboons)
(contd)
tidude routine melhodoloKy OR covers only general projects which preclude indexing at the specific level.
"Oranted si|nificanthr to above subject.
M Grant has subprojects describing specific research aspects
See Appendix for investigator's name and grant number.
CAR
»5
CAR
** R0IHIIS965 06 Etptrimintil ithirotcltrosit ind (Ititln
mtttbolism (chicks)
** ROIHl 1620604 R(|rasslon ol (Ihirosclerolic plaques
(nionktys. do|i)
** ROIHL 16219 OS Machtnisms ol athtiogenesls in chionic
unmia (Kuin»n. lats)
ROIHL 16328 06 Membrane electrical properties ol
vasculai muscle (human, animals)
M POIHL 16387 04 The blood vessel and thrombogenesis
" POIHI 16387 04 0002 The blood vessel and
thrombogenesis Hormonal ettacts on thrombogenesis
(rats, rabbits)
" POIHI 16387 04 0003 The blood vessel and
thrombogenesis Blood vessel healing (rabbits)
*' POIHL 16387 04 0008 The blood vessel and
thrombogenesis Factor VIII in hemostasis (human,
rabbits)
** ROIHL 1641903 Arterial uptake ol lipoprotein Kinetic
anahfsis (rabbits)
** ROIHL 16437 OS Drug treatment ol atherosclerosis
(rabbits, monkeys)
** ROIHL 16587 04 Cholesterol binding saponins and
atherosclerosis (monkeys)
** ROIHL 16S88 OS Collagen synthesis in atherosclerosis
(dogs. rats, rabbits, human)
ROIHL 16660-06 Phospholipid cholesterol and
phospholipid-protein interactions
ROIHL 16768-04 The sympathetic nervous system and the
arterial wall (rabbits, pigeons)
M P60HL 1726904 National heart and blood vessel research
and demonstration center
** P60HL17269-04 0001 National heart and blood vessel
research and demonstration center Atherosclerosis-
Arterial pathology and plasma lipids (human)
** P60HL1 7269-04 0003 National heart and blood vessel
research and demonstration center Atherosclerosis -Fatty
acid metabolism in cardiovascular tissue (human, chicken)
•* P60HL- 17269-04 0004 National heart and blood vessel
research and demonstration center Atherosclerosis -
Clinical surgical aspects (human)
P60HL-1 7269-04 0011 National heart and blood vessel
research and demonstration center - Lipoprotein structure
laboratory (human)
** P60HL-17269-04 0014 National heart and blood vessel
research and demonstration center - Physio-chemical nature
of lipid deposits in arterial wall (human)
P60HL17269-04 0016 National heart and blood vessel
research and demonstration center - New analytical
methodology for atherosclerosis studies
P60HL-17269-04 0033 National heart and blood vessel
research and demonstration center • Autoallergic response
in cardiomyopathy, atherosclerosis, rheumatic heart disease
" P60HL-1 7269-04 0048 National heart and blood vessel
research and demonstration center ■ Atherosclerosis -
Lipoproteins and the arterial wall (human)
ROlHL-17369-04 Arterial bypass surgery-Structure and
metabolism (monkeys)
R01HL-17371-05 Regualtion of cholesteryl ester levels in
the aorta (swine)
** ROlHL-17516-04 Role of androgen as a risk factor in
atherogenesis (human, animals)
** R01HL17517-03 Arterial wall oxygen transport in
atherosclerosis (rabbits, dogs)
ROIHLI 7576-04 Role of sphingomyelin in biomembranes
and bilayers (rats, other mammals)
** R01HL-17597-05 Role of plasma lipoproteins in
atherosclerosis (swine, human)
ROlHL-l 7623-05 Initial events in thrombus formation on
surfaces (human, rats)
P50HL17648-04 0006 Study of ischemic heart disease -
Ventricular performance and myocardial perfusion In
obstructive coronary disease
P50HL-17648-04 0020 Study of ischemic heart disease -
Core pathology laboratory-lschemic heart disease (human.
animal)
** P50HL 17648-04 0021 Study of ischemic heart disease ■
Biventricular contractile responses to acute myocardial
infarction (mammals)
P50HL-17eSS-04 0010 Study of ischemic heart disease -
Core facility-Cardiovascular pathology (human, animal)
P50HL-1 7667-04 0019 Study of ischemic heart disease -
Assessment of long-term results of coronary artery bypass
grafting (human)
P50HL-1768204 0005 Study of ischemic heart disease -
Regional myocardial perfusion deficits and segmental
contraction disorders in man
** P50HL1 7682-04 0013 Study of ischemic heart disease ■
Chronic ischemic heart disease-Myocardial function and
metabolism (dogs, swine)
** ROlHL-17721-04 Effect of sex hormones on vascular
connective tissue (rats)
ROlHl-l 7747-04 Endothelial injury and regeneration (rats)
** ROlHL-l 781805 Metabolism of cholesterol and cholesterol
in man (also rats, monkeys)
ROlHL-1782604 Oxygen delivery to tissue (rat. dog)
** ROlHL-l 7865-04 Studies on aging-Effects of sex
hormones (rats, dogs)
ROlHL-17882-04 Regulation of HMG-COA reductase and
sterol synthesis (human, mammals)
ROIHL- 1789803 Cell membranes and plasma lipoproteins
(human, swine)
ROIHL 18004 0? Transport through iittritl will
Biophysical isptcli (rabbits)
ROIHI 18060 04 Fxercise and coronary atherosclerotic
heart disease (monkeys)
ROIHI 18085 03 Neural lectors in atherogenesis (squirrel
monkeys)
ROIHI 181 52 03 Vascular Injury and atheroicltrosis
(mice, coxsackievirus)
ROIHL 181 56 02 Hemodynamics in curved arteries
ROIHL 1815704 Subcellular events in atherosclerosis
(human, rabbits, calves)
P50HL 1831803 0002 Pathogenesis and complications ol
hypertension Core experimental animal facility (rats,
rabbits)
P50HL 18318 03 0014 Pathogenesis and complications ol
hypertension Arterial metabolism and atherogenesis (rat,
rabbit)
P50HL 1831803 0015 Pathogenesis and complications of
hypertension Cultured smooth muscle cells and
microvessel metabolism (mammals)
ROIHL 1847304 Genesis of atherosclerotic lesions
(human, mules)
ROIHL 18516 03 Atherosclerosis and the arterial
contractile proteins (pigs, rabbits)
ROIHL 18519 03 Albumin, endothelium and
hemocompatibility (human, dog, cattle, rabbit)
POlHL-18574 03 Lipoprotein methodology and biomedical
applications
POlHL-18574 03 0001 Lipoprotein methodology and
biomedical applications Ultracentrifugal and
electrophoretic lipoprotein methodology -Applications
POIHL 18574 03 0004 Lipoprotein methodology and
biomedical applications - Fine structure and metabolism of
lipoproteins -EM studies (guinea pigs)
POlHL-1857403 0005 Lipoprotein methodology and
biomedical applications - Structure and function of
lipoproteins
POlHL-18574-03 0006 Lipoprotein methodology and
biomedical applications - Lipoprotein transformation,
lipolytic enzymes, diet and lipid lowering agents
POlHL-18577-03 Lipoproteins -Cell surface interactions
POlHL-18577-03 0001 Lipoproteins -Cell surface
Interactions - Structural studies of serum lipoproteins in
man and dogs
P01HL18577 03 0004 Lipoproteins-Cell surface
interactions - Analysis and chemical modification of
proteins in lipid transport (human, dogs)
ROlHL-18589-03 Psychosocial factors and outcome in
coronary disease (human)
ROlHL-186 10-03 Early intervention of age related arterial
changes (pigeon)
ROlHL-18623-12 Physical chemistry of biologically active
lipids (bacteria, plant, cattle, human)
ROlHL-18625-03
(cattle)
ROlHL-18636-02
(rats)
POlHL-18645-03
atherosclerosis
POlHL-18645-03 0001 Biology of the artery wall and
atherosclerosis - Primate arterial smooth muscle and
atherosclerosis
POlHL-18645-03 0003 Biology of the artery wall and
atherosclerosis - Synthesis of connective tissue proteins by
smooth muscle cells (human, monkeys)
POlHL-18645-03 0004 Biology of the arterv wall and
atherosclerosis - Human arterial smooth muscle cell and
lipoprotein interaction
POlHL-18645-03 0005 Biology of the artery wall and
atherosclerosis - Effects of atherosclerosis risk factors on
endothelium of the primate
POiHL-18645-03 0006 Biology of the artery wall and
atherosclerosis - The platelet and atherosclerosis (monkeys.
baboons)
POlHL-18645-03 0007 Biology of the artery wall and
atherosclerosis - Lipoprotein metabolism in subhuman
primates
ROlHL-18650-03 Platelet collagen interaction (human)
ROlHL-18682-03 Protein kinase and cholesterol
metabolism in aorta (rabbits)
R01HL18692-03 Glycosaminoglycans and lipoproteins of
human plasma
ROlHL-18723-03 Genetic heterogeneity of acid lipase-
Atherosclerosis (human)
ROlHL-18736-03 Protein transport through arterial tissue
(rabbits)
ROlHL-18793-03 Clinical-pathologic studies of sudden
cardiac death (human)
ROlHL-188 15-03 Surgical vascular disorders (human,
dogs)
POlHL-18827-02 Platelet vessel wall interactions in
thrombogenesis
POIHL-18827-02 0001 Platelet vessel wall interactions in
thrombogenesis - Role of endothelial cells in the production
of thrombi (human, cattle)
POlHL-18827-02 0005 Platelet vessel wall interactions in
thrombogenesis - Platelet vessel wall interactions in
thrombogenesis (human)
POlHL-18827-02 0006 Platelet vessel wall interactions in
thrombogenesis - Platelet immune injury in man
Organization of arterial ground substance
Fatty acids and cholesterol transport
Biology of the artery wall and
P50H1 18878 03 0005 Sp«ciall/ed ttnltr of riMiich in
thrornboll^ Plaletet inllammalory laclort in thromboftit
(human, guinea pig)
P'jOHI 1K82H0I UUOli Spitudi/ed c«nt«r ol reuiich in
thrombosis (Irology and palhogenciit ol atherotcltroiit
(rabbtl. monkey, rat, human)
ROIHL 18923 02 Steroid induted hypeilipidemia and
hypertension (human, rats)
ROIHL 18969 0? Arterial wall oxygenation (rabbits, dogt)
ROIHL 18977 03 Non invaMve diagnotii ol peripheral
arterial disease (human, dogs)
ROIHL 19001 03 Atherosclerosis in bleeder and drug
treated subiecis (pigs)
ROIHL 1908201
smooth muscle
ROIHL 19091 02
(dogs)
ROIHL 1910903
(rabbits)
ROIHL 1911203
POIHL 19242 02
Hypoxia induced relaxation ol vascular
Sustained increase in cardiac output
Regression ol chronic atherosclerosis
Ultrasonic detection of the atherosclerotic
A/S SCOR' Atherosclerosis in nonhuman
•Excludes nwtine methodok>gy OR cavers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
Atherosclerosis studies (monkeys)
Study of vascular smooth muscle
POIHL 19242 02 0001 Study of vascular smooth muscle
Energy metabolism and protein turnover in vascular smooth
muscle (rats)
POIHL 19242 02 0002 Study of vascular smooth muscle
Vascular smooth muscle response to serum lipoproteins
(rats)
POIHL 19242 02 0009 Study of vascular smooth muscle
Electrophysiology ol vascular smooth muscle (rats, chick
embryo)
ROIHL 19252 02 Vascular connective tissue- Role in
atherosclerosis (rabbits)
ROIHL 19275-03 Characterization of collateral blood
vessels (dogs)
ROIHL 19341-03
plaque
P50HL1936202
primates
P50HL 19362-02 0001 A/S SCOR-Atherosclerosis in
nonhuman primates - Effects of infant nutrition on
atherosclerosis (baboons)
P50HL- 19362-02 0002 A/S SCOR -Atherosclerosis in
nonhuman primates - Infant caloric intake, adipose tissue
development and atherosclerosis (baboon)
P50HL- 19362-02 0003 A/S SCOR-Atherosclerosis in
nonhuman primates - Heritability of characters related to
atherosclerosis (baboons)
P50HL-19362-02 0004 A/S SCOR-Atherosclerosis in
nonhuman primates - Selective breeding for characters
related to atherosclerosis (baboons)
P50HL-1936202 0005 A/S SCOR-Atherosclerosis in
nonhuman primates - Hybridization to produce primate
model of atherosclerosis (baboon. Rhesus)
P50HL- 19362-02 0006 A/S SCOR-Atherosclerosis in
nonhuman primates - Effects of cigarette smoking on
atherosclerosis (baboon)
P50HL-1936202 0007 A/S SCOR-Atherosclerosis in
nonhuman primates - Behavior type, cigarette smoking and
atherosclerosis (baboon)
P50HL- 19362-02 0010 A/S SCOR-Atherosclerosis in
nonhuman primates - Antihypertensive tberapy-
Atherogenesis in experimental hypertension (baboon)
P50HL-19362-02 0011 A/S SCOR-Atherosclerosis in
nonhuman primates - Chronic hypertension induced by
operant conditioning techniques (baboon)
P50HL-19362-02 0012 A/S SCOR-Atherosclerosis in
nonhuman primates - Induction of chronic hypertension by
salt loading (baboon)
P50HL 1936202 0013 A/S SCOR-Atherosclerosis in
nonhuman primates - Core laboratory-Lipid biochemistry
(baboons)
P50HL-19362-02 0014 A/S SCOR-Atherasclerosis in
nonhuman primates - Core laboratory-Behavior observation
and manipulation (baboon)
P50HL 1936202 0015 A/S SCOR-Atherosclerasis in
nonhuman primates - Core laboratory-Pathology and
morphometry (baboons)
P50HL-19362-02 0016 A/S SCOR-Atherosclerosis in
nonhuman primates - Core laboratory-Animal services
(baboon)
P50HL-19362-02 0017
nonhuman primates
statistical analysis
ROlHL-19399-02 Atherosclerosis-Early events and
regression factors (rats)
ROIHL 19406-03 Grading of atherosclerosis by CW doppler
ultrasound (human, dogs)
ROlHL-19451-03 Functional characteristics of the left
heart
ROlHL-1945103 0004 Functional characteristics of the
left heart ■ Quantitative coronary arteriography (human)
R01HL19454-02 Rheological factors in transport across
arterial wall (dogs)
ROlHL-19459-03 Dynamics of atherogenesis and
lipoprotein formation (human, rabbit)
ROlHL-19767-01 Pathochemistry of fibrinogen (humans)
ROlHL-19820-02 The chemistry and biological effects of
heparin (Rhesus, human, other mammals)
ROlHL-19830-02 Shear to aortic histamine synthesis and
permeability (dogs)
ROlHL-19936-02 Unsaturated fatty acid biosynthesis in
the aorta (rats)
(contd)
A/S SCOR-Atherosclerosis in
Core laboratory-Data management.
CAR
ROlHL-201 14-02 Collagen-platelet interaction and human
aorta collagen (human)
ROlHL-20183-02 Portacaval shunt as treatment for
hyperlipemia (pigs)
** ROlHL-20189-01 Effects of renin on atherogenesis
(rabbits)
ROlHL-20197-02 Maintenance and repair of vascular
endothelium (human, animals)
ROlHL-20218-02 Fibrinogen catabolism and intravascular
coagulation (human)
ROlHL-20350-02 Crystal structure of lipids-Cholesterol
ROlHL-20381-03 Long-term study of diabetic vascular
disease (human)
ROlHL-20397-03 VLOL-TG metabolism in diabetes mellitis
(human, rat)
ROlHL-20411-03 Platelet fatty acid metabolism in
diabetes (rat, rabbit, guinea pig)
** ROlHL-20418-03 Serum cholesterol binding reserve in
diabetes (human)
** ROlHL-20428-03 The juvenile diabetic heart (human)
ROlHL-20447-03 Connective tissue and diabetic vascular
disease (human)
** ROlHL-20460-03 Aortic histamine synthesis in diabetes
(rat)
** ROlHL-20471-03 Atherosclerosis and diabetes mellitus
(human)
ROlHL-20483-03 Sterol balance and cholesterol absorption
in diabetics (human)
** ROlHL-20488-03 Cholesterol metabolism in diabetic man
** ROlHL-20508-03 Diabetes, hyperglycemia and
cardiovascular disease (human)
** ROlHL-20517-03 Diabetes, somatotropin, factor VIII and
atherosclerosis (human, animal)
** ROlHL-20522-03 Peripheral arterial disease in the diabetic
(human)
ROlHL-20539-03 Blood glucose, hemoglobin Ale. and
diabetic vascular disease (human)
** ROlHL-20564-02 Pathogenesis of peripheral arterial
disease (rats, rabbits)
ROlHL-20597-02 Electrophysiologic correlates of
myocardial ischemia (human, dogs, rabbits)
ROlHL-20630-03 Development of a pulsed Doppler velocity
detector (human, animals)
ROlHL-20662-02 Physical activity, fitness and
epidemiology of CHD
ROlHL-20764-02 Elastin and calcification in pulmonary
and vascular disease (human, mammals)
ROlHL-20829-02 Fluid mechanics of heart valve
prostheses (dogs, human)
** ROlHL-20895-03 0009 Cineangiographic studies of
cardiovascular system - Aortic changes in atheromatosis
(rabbits)
ROlHL-20898-02 Ultrasonic evaluation in direct arterial
surgery (models, cattle, human)
** ROlHL-20924-02 Atherosclerosis and arterial cell functions
(human, rabbits)
M P01HL-20948-02 Molecular basis of cholesterol
metabolism
** POlHL-20948-02 0001 Molecular basis of cholesterol
metabolism - Biochemical and ultrastructural
characterization of LDL in human fibroblasts
*• POlHL-20948-02 0002 Molecular basis of cholesterol
metabolism - LDL pathway in cell lines with informative
properties other than fibroblasts
** POlHL-20948-02 0004 Molecular basis of cholesterol
metabolism - Genetic analysis of the LDL pathway (human)
M POlHL-20993-02 Population dynamics of arterial cells in
atherogenesis
** POIHL 20993-02 0001 Population dynamics of arterial
cells in atherogenesis - Arterial SMC population dynamics
in atherogenesis (swine)
'* POlHL-20993-02 0002 Population dynamics of arterial
cells in atherogenesis - Arterial endothelial dynamics In
atherogenesis (swine)
** POlHL-20993-02 0003 Population dynamics of arterial
cells in atherogenesis - Clonal phenomena in atherogenesis
(human, hares)
** POlHL-20993-02 0004 Population dynamics of arterial
cells in atherogenesis - Modifications of cholesterol balance
related to arterial cell divisions (swine)
** POlHL-2099302 0005 Population dynamics of arterial
cells in atherogenesis - Drugs other than hypolipidemic
drugs affecting atherosclerosis (swine, rabbits)
" POlHL-2099302 0006 Population dynamics of arterial
cells in atherogenesis ■ Mechanism of regression of
atherosclerosis by diet and injury (swine)
** POlHL-20993-02 0007 Population dynamics of arterial
cells in atherogenesis Interaction of lipoproteins in
hypercholesteremia (human, swine)
** POIHL 20993-02 0008 Population dynamics of arterial
cells in atherogenesis • Angiotoxicity of cholesterol
oxidation In atherogenesis (rabbits)
** POlHL-20993-02 0009 Population dynamics of arterial
cells in atherogenesis - Mathematical biology-Core
•* POlHL-20993-02 0010 Population dynamics of arterial
cells in atherogenesis • Animal care and development and
standardization of animal models -Core
** POlHL-20993-02 0011 Population dynamics of arterial
cells in atherogenesis - Light and electron microscopy
laboratories -Core
M P50HL-21006-02 Specialized center of research in
arteriosclerosis
96
** P50HL-21006-02 0001 Specialized center of research in
arteriosclerosis • Clinic and core program
P50HL-2 1006-02 0002 Specialized center of research In
arteriosclerosis - Turnover and metabolism of cholesterol In
man
P50HL-21006-02 0004 Specialized center of research in
arteriosclerosis - Regulation of growth of human arterial
smooth muscle cells by platelets
P50HL-2 1006-02 0005 Specialized center of research In
arteriosclerosis - Regional myocardial perfusion in patient
with coronary artery disease (also dogs)
** ROlHL-21010-02 Glycemia. other traits and CV death in
40,000 persons
** ROlHL-21032-02 Injury, wall thickness, and arterial wall
oxygenation (dogs, rabbits)
** ROlHL-21088-02 Genetic patterns in deaths from Ml and
stroke in Utah
ROlHL-21188-02 Pulsatory water flux and endothelial cell
desquamation
ROlHL-21217-01 Ion and 5-hydroxytryptamine transport by
platelets
** R01HL-21260-02 Risk factor relationships of
atherosclerosis (monkeys)
** ROlHL-21270-01 Correlation of arterial hemodynamics and
morphology (human)
** R23HL-21279-02 Angiographic estimation of
atherosclerotic wall thickness
R23HL-21298-02 Coronary vasomotion (dogs, pigs)
** ROlHL-21303-02 Collagen synthesis by cultured human
vascular cells
R23HL-21320-02 Cyclic nucleotide metabolism in vascular
endothelium
** ROlHL-214 16-02 Atherosclerosis in new modles of
diabetes mellitus
** ROlHL-21429-02 Transport of LDL in arterial wall (human,
mammals)
ROlHL-2 1438-02 Structure and permeability of arterial
endothelium (pigs)
** ROlHL-21460-02 Lipoproteins, hemostasis and
atherosclerosis (human, rabbits)
*• ROlHL-21513-02 Metabolism of trans fatty acids (human,
rats, swine)
ROlHL-21533-02 Platelet inhibitor drug in coronary surgery
(human)
** R23HL-21559-01 Oxygen supply and blood flow through
aortic vasa vasorum (dogs)
** ROlHL-21592-01 Lipoproteins and coagulation factors in
atherosclerosis (pigeons)
** ROlHL-21665-01 Collagen polymorphism and arterial
structure (monkeys, guinea pigs)
ROlHL-2175611 Vascular disease-Cytochemistry and
ultrastructure (human, rats, mice, hamsters)
ROlHL-21764-01 Ultramicroanalysis of prostaglandins and
related compounds (rats)
** ROlHL-21912-01 Biosynthesis of lipoic acid and
atherosclerosis (birds, chick embryos)
** ROlHL-2197101 Atherosclerotic disease and risk factors
in twins (human)
** R01HL-22040-01 Regulation of lysyl-cross-linking in
vascular tissue (rats, turkeys)
** ROlHL-221 15-02 Lipid-mobilization and diabetic
atherosclerosis (human)
** ROlHL-221 23-02 The role of the red cell in diabetic
atherosclerosis (human)
** ROlHL-22341-01 Pathogenesis of atherosclerosis in rats
** ROlHL-22474-01 Cholesterol metabolism and
atherosclerosis (rats, human, rabbits)
** ROlHL-22527-01 Prostacyclin-thromboxanes in the
cardiovascular system (human, rabbits)
M POlHL-2260201 Pathophysiology of the endothelium
** POlHL-22602-01 0001 Pathophysiology of the
endothelium ■ Plateletendothelial interactions in vitro
(human, cattle)
** POIHL 22602-01 0002 Pathophysiology of the
endothelium • Molecular charge and endothelial
permeability (rats, mice)
** POlHL-22602-01 0004 Pathophysiology of the
endothelium - Endothelium, platelets smooth muscle and
atherosclerosis (rabbits)
R23HL-22621-01 Blood cell-mediated pulmonary (human)
** ROlHL-22623-01 Polyamines cellular mediators of
atherogenesis (human)
M POlHL-22633-01 Cellular and molecular biology of
lipoprotein metabolism
** POlHL-22633-01 0001 Cellular and molecular biology of
lipoprotein metabolism ■ Secretion of lipoproteins by the
perfused liver (rats, rabbits)
** POlHL-22633-01 0002 Cellular and molecular biology of
lipoprotein metabolism - Sterol metabolism in tissue
culture cells
** R23HL-2266901 Cardiovascular effects from visceral
afferents (dogs)
** ROlHL-2268201 Structure and function of high density
lipoprotein (human, rat)
** ROlHL-22739-01 Evolution and progression of pediatric
atherosclerosis
ROlHL-22741-01 Arteriovenous connections in extremity
revascularization (dogs)
** ROlHL-2278301 Hemodynamic induction of intimal
fibromuscular lesion
ROIHL-2284701 Test for adherence to diets rich in
linoleic acid
CAR
** ROlHL-22893-01 Evaluating arterial disease by velocity-
wave analysis (dogs, human)
ROlHL-22946-01 Prostaglandins, platelet aggregation and
vasoactivity (human, rats, rabbits)
** ROlHL-23003-01 Bulk-surface distribution of cholestetyl
esters
** ROlHL-23599-01 Mechanisms of ischemic rhythm
disorders (dogs)
** N01HV12156-10 Lipid research clinic
NOlHV-12157-14 Lipid research clinic (human)
** NOlHV-12158-10 Establishment of a lipid research clinic
** N01HV-12159-09 Lipid research clinic
** NOIHV 12160-15 Establishment of a lipid research clinic
** NOlHV-2291309 Lipid research clinic
** NOlHV-22914-08 Establishment of a lipid research clinic
NOlHV-22915-11 Establishment of lipid research clinic
NOlHV-22916-16 Establishment of a lipid research clinic
NOlHV-22917-11 Lipid research clinic (human)
NOlHV-2293209 Establishment of a lipid research clinic
** NOlHV-32931-09 Establishment of a lipid research clinic
center
** NOlHV-52966-01 Development and evaluation of an
ultrasonic imaging system (swine)
N01HV-53015-09 Establishment of a lipid research clinic
(human)
** NOlHV-5302904 Nonhuman primate models of
atherosclerosis
** N01HV-5303005 Nonhuman primate models of
atherosclerosis and hypertension
** NOlHV-53031-04 Nonhuman primate models of
atherosclerosis and hypertension
** NOlHV-6290502 Non-human primate models of
arteriosclerosis
** NOlHV-7292404 Non-invasive detection of atherosclerotic
lesions (human, animals)
** NOlHV-7292504 Non-invasive detection of atherosclerotic
lesions (human, monkeys, dogs)
NOlHV-72925-04 Ultrasonic imaging development
** NOlHV-7292700 Systems for non-invasive detection of
atherosclerotic lesions (human)
** NOlHV-72928-04 Develop high resolution ultrasonic
imaging techniques
** NOlHV-72929-01 Improved detection of atherosclerosis
(human, dogs)
** NOlHV-72930-02 Atherosclerosis assessment-Angiography
and ultrasound (dogs, human)
** NOlHV-72931-02 Non-invasive detection of atherosclerotic
lesions (human, dogs)
** NOlHV-72932-00 Non-invasive detection of atherosclerotic
lesions (human, phantoms)
** NOlHV-72978-02 Development of models of hypertension
** NOlHV-72980-02 Development of models of hypertension
CARDIOVASCULAR DISORDERS,
ARTERIOVENOUS SHUNTS ABNORMAL
SEE ALSO CARDIOVASCULAR SYSTEM. DUCTUS ARTERIOSUS
EMBRYONIC
** P01HL15194-07 0011 Pathophysiology of
cardiopulmonary dysfunction - Distribution of ventilation-
Oxygen effects on intrapulmonary shunting (human)
ROlHL-15448-06 Surgical and metabolic aspects of
venous grafts, (dogs, monkeys, rabbits)
R01HL16658-05 Intrarenal regulation of sodium
reabsorption
POlHL-18576-03 0010 Thrombosis research program
project - Evaluation of non-thrombogenic materials (cattle)
** ROlHL-19225-02 0002 Types and mechanims of
pulmonary hypertension - Effect of aorto-pulmonary shunt
(pigs)
ROlHL-19225-02 0003 Types and mechanims of
pulmonary hypertension - Cardiopulmonary function in pigs
and rats
ROlHL-2067802 Cardiovascular adaptation to stress in
disease states (dogs)
ROlHL-21657-01 Regional non-ischemic myocardial
hypoxia (dogs)
ROlHL-22482-01 Circulatory hemodynamics and sodium
excretion (dogs)
CARDIOVASCULAR DISORDERS, ARTERITIS
SEE ALSO CEREBROVASCUUR DISORDERS. TEMPORAL
ARTERITIS
SEE ALSO KIDNEY DISORDERS. GLOMERULONEPHRITIS
** ROlHL-1953903 Pathology of hypertensive-associated
arteritis (rabbits)
** ROlHL-22939-01 Human kinin and fibrinolytic systems
and renal disease (human)
CARDIOVASCULAR DISORDERS, EMBOLISM
SEE ALSO CARDIOVASCULAR DISORDERS. ARTERIAL
OCCLUSIONS
SEE ALSO CARDIOVASCULAR DISORDERS. VENOUS
OCCLUSIONS
SEE ALSO CARDIOVASCULAR SURGERY. VASCULAR
OCCLUSION THERAPEUTIC
POlHL-0628518 0208 Cardiovascular-respiratory
physiology and biochemistry - Composition, properties and
turnover of pulmonary surfactant (human, animals)
P01HL08805-15 0045 Regulation of ventilation and
pulmonary circulation - Integrated description of
neurochemical respiratory control system
(contd)
•Excludes routine methodotogy OR covers only general proieds which preclude indexing at the specific level
**Onented significantly to above subject.
M Grant lias subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
CAR
PUIHI 08899 14 00?9 lolarance to KspiintorY gates in
haalth and disaasa Isobanc |as countei ditlusion
phanomana (liuniana pigs)
•* POIHI 11414 II 002; Ihfombosis and atheiosciafosis
piogiam Thaimal mamoty wiie liltai lo piavaiil piilmonaiy
ambolism (human, dogs)
ROIHL 1I80M0 Cardiovascular surgical lesearch (dogs.
shaap. swina. cats, monkays)
ROIHI I2S30 10 Emphysema Respiratory function in
disease (human, dogs, lats)
" ROIHL 13466 08 Pulmonary platelets in shock, trauma
and embolliation (dogs, pigs, rats)
•* PbOHL 14187 07 0008 Pulmonary SCOR Chemical
mediators in pulmonary vascular responses Pulmonary
thiomboembolism (dogs, human)
PSOHL 14217 08 00S2 Speciali2ed center ol research in
thrombosis Radioisotope nuclear medicine section
(human, dog)
POIHL 1498507 0007 Adaptation to hypoxia Control of
pulmonary circulation, histamine and the sympathetics
(animals)
P01H11498507 0010 Adaptation to hypoxia Pulmonary
mast cell (animals)
POIHL I498S07 0011 Adaptation to hypoxia
Prostaglandins in the control o< the pulmonary circulation
(animals)
POIHL 1548606 0006 Studies on thrombosis - Clinical
investigation unit
R01HL1558006 Humoral control ot pulmonary and
systemic circulation (animals)
•* P01HL1559605 0007 Coagulation, fibrinolysis,
hemostasis and hepatitis Structural studies and
fractionation ol urokinase (human)
ROIHL 16938-05 Effect of physical forces on blood (dogs.
human)
P60HL-1 726504 0007 Community blood resource center
support ' Research-Massive transfusion and trauma
(human)
R01HL1735504 Pulmonary vascular adjustments in
circulatory collapse (dogs, rats)
P50HL- 17665-04 0027 Study of ischemic heart disease -
Positron imaging of regional myocardial perfusion (human,
dog)
POlHL-17731-04 0006 Physiological basis of pulmonary
disease - Ventilation-perfusion ratios (human, dogs)
POlHL-17813-04 0001 Lung disease and the oxygenation
of blood and tissue • Diffuse interstitial lung disease-
Pathophysiology (human, dogs)
ROlHL-1 7821-03 Cavitation phenomena near prosthetic
devices
** ROlHL-18070-04 Regulation of intrapulmonary airways
and vessels (human, animals)
ROlHL-18288-04 Intraoperative protection of the
myocardium (dogs, rats)
** POIHL 1857603 0013 Thrombosis research program
project - Early warning and monitoring test systems in
thrombotic disease (human)
ROlHL-188 15-03 Surgical vascular disorders (human,
dogs)
** P50HL-19155-02 0004 Pathophysiology of pulmonary
edema - Physical and chemical effects of multiple
pulmonary emboli (sheep)
ROlHL-19173-03 Analysis of blood trauma from
microporous oxygenators (human, dogs, rabbits)
R01HL19993-02 Optical detection of platelet aggregates
(human, baboons)
** ROlHL-20554-02 Memoryalloy-filters for venous emboli
(dogs)
** R01HL-21518-01 Improvement in regional ventilation-
perfusion resolution (human)
M P01HL-22163-01 Surface thrombogenesis-Mechanisms and
prevention
** POlHL-22 163-01 0002 Surface thrombogenesis-
Mechanisms and prevention - Laser-scattering detection of
microemboli in blood flow (baboons)
** POlHL-2216301 9001 Surface thrombogenesis-
Mechanisms and prevention - Polymers for studing blood-
material interactions core
ROlHL-2285201 Diagnostic techniques in venous
thromboembolism (human)
CARDIOVASCULAR DISORDERS, EMBOLISM, AIR
POlHL-08899-14 0056 Tolerance to respiratory gases in
health and disease - Extension of pulmonary oxygen
tolerance at increased pressures (animals)
POlHL-08899 14 0072 Tolerance to respiratory gases in
health and disease - Inert gas exchange isobaric gas
counterdiffusion and decompression
POIHL-08899-14 0074 Tolerance to respiratory gases in
health and disease - Biomathematical analysis of isobaric
gas exchange and bubble formation
POlHL-08899-14 0076 Tolerance to respiratory gases in
health and disease Bubble formation during gas
counterdiffusion (hamsters)
POlHL-08899-14 0078 Tolerance to respiratory gases in
health and disease - Isobaric gas counterdiffusion-Sensory,
cutaneous and systemic function (animals)
•• POlHL-08899-14 0079 Tolerance to respiratory gases in
health and disease - Physiological factors in
counterdiffusion bubble formation (human, pigs)
•* POlHL-08899-14 0080 Tolerance to respiratory gases in
health and disease - Dynamic quantitation of continuous
isobaric gas embolization
97
POIHL 08899-14 0089 Tolartnca lo rtiplriloiy |iim In
health and diMfU < Otcompriision by appilcilioni of
optimal control Ihaory
ROIHI 12174 II Venlilatiun/perfuslon distribution in the
lung (human, mammal)
ROIHI 16254 05 Palhogrni-bis ot bubble and clot
formation (fish)
** ROIHL 16855 03 Cavitation in biological systems
(microorganisms, animals)
** ROIHL 17503 03 Vascular bubbles in decompression
sickness (minipig, dog, goat)
ROIHL 22413 01 Enhanced detection of bubbles in
Doppler flow signals (human)
CARDIOVASCULAR DISORDERS, EMBOLISM, FAT
ROIHI 184 73 04 Genesis of atherosclerotic lesions
(human, mules)
** ROIHL 1860703 Metabolic and drug studies on
experimental fat embolism (mice)
CARDIOVASCULAR DISORDERS, EMBOLISM,
THROMBOEMBOLISM
R01HL01601 30 Blood coagulation and hemorrhagic
disease (horseshoe crabs)
*• POlHL-1 13 1012 0095 Mechanisms of cardiovascular
disease - Blood and transfusion disorders (human, rats,
monkeys)
POIHL 11414 11 0028 Thrombosis and atherosclerosis
program Catecholamine metabolism in the lung (rat)
** ROIHL 11686-09 Dynamics of thrombus formation and
dissolution (human, chickens)
POlHL-13738-08 0005 Cardiac assist devices and
artificial hearts - Development of new materials for
artificial heart and assist devices (sheep, dog)
** ROlHL-13754 08 Postoperative thromboembolism in
surgical patients (human)
P50HL-14147-08 0007 Specialized center of research in
thrombosis - Radioactive tracers in recognition of
intravascular coagulation (human, dogs)
P60HL- 151 5807 0011 Comprehensive sickle cell center -
Clinical services-Adult patients
ROlHL-15593-05 Prolonged extracorporeal cardiopulmonary
support (rats, sheep, rabbits)
M POlHL-16387-04 The blood vessel and thrombogenesis
** POlHL-16387-04 0002 The blood vessel and
thrombogenesis Hormonal effects on thrombogenesis
(rats, rabbits)
" POlHL-16387-04 0003 The blood vessel and
thrombogenesis - Blood vessel healing (rabbits)
** POlHL-16387-04 0004 The blood vessel and
thrombogenesis - Analysis of vascular basement membrane
by enzymatic methods (human)
** POlHL-16387-04 0005 The blood vessel and
thrombogenesis - Fluid engineering considerations in
thrombogenesis
** POlHL-16387-04 0008 The blood vessel and
thrombogenesis - Factor VIII in hemostasis (human.
rabbits)
** ROlHL-16646-05 Pathobiology of thromboembolic disorders
(human)
M POlHL-17419-04 Studies on mechanisms of hemostasis
" POlHL-174 19-04 0003 Studies on mechanisms of
hemostasis - Characterization of fibrinogen (human)
** ROlHL-17516-04 Role of androgen as a risk factor in
atherogenesis (human, animals)
POlHL-17731-04 0006 Physiological basis of pulmonary
disease - Ventilation-perfusion ratios (human, dogs)
POlHL-18208-04 0001 Center for the study of blood cell
rheology Physiological basis of reversible erythrocyte
shape change (human, firefly)
** ROlHL-18333-05 Thrombogenesis and hemostatic balance
(rabbits, human)
ROlHL-18738-02 Prevention of postoperative venous
thrombi (human, cattle)
** POlHL-18827-02 0007 Platelet vessel wall interactions in
thrombogenesis - Biochemistry and role factor V in
thrombogenesis (human, cattle)
ROlHL-19255-03 Evaluation of diagnostic clinical
hcmorrheology (human)
ROIHL 19270-03 Effects of erythropoiesis on platelets and
hemostasis (rats)
** ROlHL-202 18-02 Fibrinogen catabolism and intravascular
coagulation (human)
ROlHL-21431-02 Factor II antigen and coagulant activity
(human, animals)
** ROlHL-21548-01 Pathogenesis of pulmonary
thromboembolic disease (human, mammals)
'* ROlHL-22852-01 Diagnostic techniques in venous
thromboembolism (human)
NOlHV-72939-01 Develop and evaluate left heart assist
blood pumps (human, calves, pigs)
CARDIOVASCULAR DISORDERS, HEMORRHAGE
SEE ALSO BLOOD AND RE DISORDERS. HEMORRHAGIC
DISORDERS
SEE ALSO BLOOD STASIS
SEE ALSO CEREBROVASCULAR DISORDERS. CEREBRAL
HEMORRHAGE
SEE ALSO CEREBROVASCUUR DISORDERS. MENINGEAL
HEMORRHAGES
SEE ALSO EYE CIRCULATORY DISORDERS. RETINAL
(INCLUDING VITREOUS) HEMORRHAGE
•Excludes routine methodokigy OR covers only general projects which preclude indexing
"Oriented significanthi to atMve subiect
at the specific level
M Grant has subprojeds deschbing specific research aspects.
See Appendix for investigator's name and grant number
CAR
Sff AlSOfiASfROINirSIINAI riRruiAIORY OISOROIR'..
IIIM()RRIIA(,f i.AMNIJINIIMINAI
ROIHI I0H8I n Structure and lundion of
inirrocirculalion (hamittrs. rait, i.ilt. dogtl
POIHI 116/8 II 0077 Cardiovttcular dynamics and Ihtir
(onliol Vasopressin and thirst in control ol body fluid
volumes and osmolality (dogs)
" POIHI 123/3 10 0013 Cardiopulmonary physiology and
pathophysiology Effects of cardioviuulir dru|t on Itft
vontrirutar function (dogs)
ROIHI 12415 10 Evaluation ol left ventricular lundion
(dogs, rabbits)
P50HL 14214 0/ 0031 Newborn lung center for hyaline
membrane disease Essential fatty acid deficiency and
HMD (human)
ROIHL 14529 07 Systems analysis of baroretlei (dogs)
ROIHL 1541606 Cardiovascular control in normal and
disease states (dogs, baboons)
POIHL 16910 05 0005 Regulation of the peripheral
circulation Control of circulation by baroreceptor and
chemoreceptor reflexes (dog. monkey)
POIHL 16910 05 0006 Regulation of the peripheral
circulation Regulation of blood (low diilribulion (baboons,
dogs)
ROIHL 1691604 0011 The role of albumins in lung water
accumulation Whole body distribution and exchange of
albumin (rabbits, human, monkeys)
P60HL 17265 04 0007 Community blood resource center
support Research- Massive transfusion and trauma
(human)
ROIHL 18586-03 Role of platelet lipids in hemostasis and
thrombosis (human)
ROIHL 18672-03 Dynamic studies of clot structure
formation (human)
ROIHL 18995-04 Cardiovascular determinants of
catecholamine release (dogs)
ROIHL 20399 03 Vascular control in experimental diabetes
mellitus (dog)
ROIHL 20429-03 Study of effects of diabetes reactivity
(miniature pigs, rats)
ROlHL-20787 02 Thromboxanes and prostaglandins-
Biochemical pharmacology (rabbits, human)
ROlHL-20864-01 Postnatal maturation of cardiovascular
regulatory system (minipig)
ROlHL-21094-01 Arterial baroreceptors and renal function
(dogs)
** ROlHL-22641-01 Ventilation, perfusion, and systemic
arterial reflexes (dogs)
ROlHL-23618-01 Substrate metabolism m isolated
myocytes in shock (dogs, rats, guinea pigs)
CARDIOVASCULAR DISORDERS, HEMORRAGIC
SHOCK
ROlHL-00487-29 Vasomotor tone and venous return
(human, dogs, monkeys )
** ROlHL-02363-20 Kinetics of water and electrolytes in
shock (dogs, rats)
ROlHL-03181-21 0029 Hemodynamics as applied to
surgical problems - Indocyanine green clearance for
estimation of hepatic blood flow (human)
** ROlHL-05875-18 Pathologic metabolic and physiologic
studies of heart (human, dogs, cats)
** POlHL-07896-15 0054 Environmental biomedical research
program - Myocardial effects of hemorrhagic shock (dogs)
POlHL-08682-15 0019 Regulation of the cardiovascular
system - Hepatic immunophysiology and host-defense in
shock (rat, dog, human)
POlHL-08682-15 0020 Regulation of the cardiovascular
system - Hepatic metabolic basis of shock (rat)
POlHL-08682-15 0036 Regulation of the cardiovascular
system - Electrolyte transport in myocardium with
hemorrhagic shock (rats)
*♦ POlHL-11678-11 0043 Cardiovascular dynamics and their
control - Basic mechanisms of circulatory shock (dog)
** POlHL-11678-11 0068 Cardiovascular dynamics and their
control - Basic hemodynamics (rats, dogs)
ROlHL-11906-11 Comparative study of heart function
(cats, rats, hedgehogs, squirrels)
** ROlHL-12421-10 Pathophysiology of circulatory shock
(dogs, baboons)
** ROlHL-12690-09 Systemic and local vascular adjustment
in shock (monkeys, cats)
POlHL-12738-10 0069 Physiologic pharmacology and its
clinical applications - Blood rheology in coronary heart
disease (dogs)
" ROlHL-13193-09 Pathophysiology of post-traumatic and
shock states (rodents, dogs)
ROlHL-13341-06 Lymph -An indication of splanchnic tissue
respiration (dogs, human, rats)
ROlHL-13466-08 Pulmonary platelets in shock, trauma
and embolization (dogs, pigs, rats)
ROlHL-14693-07 Survival value of physiological responses
to hypoxia (dogs)
ROlHL-15607-06 Physiological control of splanchnic
circulation (dogs)
ROlHL-15758-06 Catecholamine release in the heart
(dogs)
POlHL-15832-06 0007 Chemical-structural predispositions
to lung injury - Inactivation of vasoactive agents by the
lung (human, rats. cats, dogs)
ROlHL-16489-04 Renal prostaglandins-Synthesis and
function (human, dogs, rats)
(contd)
CAR
** ROlHL-17091-05 Anesthetics and microvascular response
to hemorrhage (rats)
P60HL17269-04 0024 National heart and blood vessel
research and demonstration center - Section of
experimental cardiovascular surgery -Core facility
** ROlHL-17355-04 Pulmonary vascular adjustments in
circulatory collapse (dogs, rats)
** ROlHL-18002-03 Circulatory shock, trauma and RE-system
function (rats)
ROlHL'18015-03 Pharmacologic studies on vascular
smooth muscle (dogs, rats)
** ROlHL-18731-02 RES stimulating materials in
experimental shock (dogs)
ROlHL-18762-03 Posttraumatic pulmonary insufficiency
(dogs)
ROlHL-18866-02 Microvascular flow, volume, and
reactivity (rats, cats)
** P50HL19185-02 0006 Pulmonary SCOR-Neonatal
respiratory distress syndromes ■ Evaluation of risk factors
in neonatal respiratory distress (human, sheep)
ROIHL 19255-03 Evaluation of diagnostic clinical
hemorrheology (human)
ROlHL-19673-03 Surgical aspects of shock and hypoxia
(dogs, monkeys, rats)
R01HL-19725-03 Complement induced pulmonary injury
(dogs, rabbits, sheep)
** R01HL19977-02 Genesis of circulatory shock by
pancreatic peptides (cats, dogs)
ROlHL-20177-02 Effects of erythrocyte deformability on
tissue perfusion (rats)
** ROlHL-21076-02 Lung fluid, protein exchange after
hemorrhagic shock (sheep)
ROlHL-21843-01 Ischemia, diabetes and the
microcirculation (rats, cats, hamsters)
ROlHL-22172-01 Hypotension, renal ischemia and effect of
mannitol (dogs, rats)
ROlHL-22435-02 Pulmonary alveolar-capillary permeability
characteristic (dogs)
** R23HL-22972-01 Microcirculatory function in hypotension
(rats, hamsters)
CARDIOVASCULAR DISORDERS, HYPERTENSION
(SYSTEMIC)
SEE ALSO ADRENAL GLANDS DISORDERS, ADRENAL
HYPERTENSION
SEE ALSO BODY FLUID BALANCE, EDEMA
SEE ALSO CARDIOVASCULAR AGENTS, ANTIHYPERTENSIVE
AGENTS
SEE ALSO KIDNEY-CIRCUUTORY DISORDERS, RENAL
HYPERTENSION
SEE ALSO KIDNEY-CIRCULATORY DISORDERS, RENOPRIVAL
HYPERTENSION
SEE ALSO LIVER CIRCUUTORY DISORDERS, PORTAL
HYPERTENSION
SEE ALSO MAMMALS, RODENTS, MYOMORPHA, SPONTANEOUS
HYPERTENSIVE RATS*
SEE ALSO NATIONAL HIGH BLOOD PRESSURE EDUCATION
RESEARCH PROGRAM COMMITTEE
SEE ALSO PREGNANCY TOXEMIAS AND HYPERTENSION
SEE ALSO RESPIRATORY CIRCULATORY DISORDERS,
PULMONARY HYPERTENSION
ROIHLO 1803-23 0017 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Contractile and relaxing proteins of blood
vessels and platelets (mammals, human)
** P01HL-03174-23 0001 Mechanisms of acute vascular
reaction to injury - Response of the vascular intima to
injury (human, rats)
** P01HL-03174-23 0013 Mechanisms of acute vascular
reaction to injury ■ Surface morphology of the aorta in
normal and injured states (rats, rabbits)
** ROlHL-03181-21 0028 Hemodynamics as applied to
surgical problems • Extrarenal factors in the hypertension
of coarctation (dog)
POlHL-04664-18 0001 Cardiovascular and lung dynamics
■ X-ray projection image videodensitometry (dogs)
POlHL-06296-18 0002 Cardiovascular and pulmonary
adaptation to stress - Respiratory muscle blood flow,
mechanics and metabolism (human, dog)
POlHL-06296-18 0003 Cardiovascular and pulmonary
adaptation to stress - Human exercise studies (human,
dogs)
POlHL-06314-17 0064 Immunologic mechanisms in
cardiovascular disease - Diabetic vascular disease (human,
rats, mice)
** ROlHL-06736-18 Biogenicmechanlcal factors in
microcirculation (rats, gerbils)
POlHL-06835-17 0021 Cardiovascular disease - Animal
study in atherosclerosis (dog, guinea pig)
POlHL-0683517 0022 Cardiovascular disease ■ Arterial
lipogenesis from glucose in the rat
** POlHL-06835-17 0024 Cardiovascular disease ■ Studies
on the obese spontaneously hypertensive rat
** POlHL-06835-17 0046 Cardiovascular disease ■
activity during salt depletion in essential hypertension
(human)
** POlHL-06835-17 0051 Cardiovascular disease -
Cardiopulmonary volume in hypertension (human)
** POlHL-06835-17 0052 Cardiovascular disease
distenslbility (human)
** POlHL-0683517 0053 Cardiovascular disease -
Vasodilating drugs (human)
•* POlHL-06835-17 0057 Cardiovascular disease - Studies
on cardiac hypertrophy
Renin
Aortic
98
* POlHL-07896'15 0055 Environmental biomedical research
program - Cerebral blood flow by Xenon-133 inhalation
(human)
POlHL-08974-14 0005 Natural and experimental
atherosclerosis - Atherosclerosis, coronary heart disease
and sudden death (human)
POlHL-08974-14 0028 Natural and experimental
atherosclerosis - Geographic pathology of atherosclerosis
and coronary heart disease (human)
* ROlHL-09622-14 Pathogenesis of atherosclerosis (rats)
ROlHL-10160-13 Origins of atherosclerosis (human)
R01HL10182-13 Circulatory function and electrolytic
metabolism (dogs, human)
ROlHL-10384-13 Blood flow and nucleotide metabolism
(animals)
POlHL-10436-13 0001 A multidisciplinary study of
congenital heart disease - Assessment of the outlook for
children with congenital heart disease
POlHL-10436-13 0008 A multidisciplinary study of
congenital heart disease ■ Physiologic consequences of
chronic hypoxemia (human)
POlHL-10539-12 0066 Pathophysiology of circulation -
Usefulness of relaxation response In industrial settings
** POlHL-10539-12 0070 Pathophysiology of circulation -
Effects of hypertension on myocardial blood flow after
coronary occlusion (dogs)
** R01HL1061213 0019 Humoral factors in heart failure
and hypertension - Pathogenesis of hypertension in the
spontaneous hypertensive rat
ROlHL-106 12-13 0021 Humoral factors in heart failure
and hypertension - The control of aldosterone secretion
(dogs)
** ROlHL-10711-12 Cooperative study of treatment of
hypertension (human)
** ROlHL-1088113 Structure and function of
microcirculation (hamsters, rats, cats, dogs)
ROIHLI 1289-12 Analysis of stress in pulsatile dynamics
POIHLI 13 10-12 0087 Mechanisms of cardiovascular
disease - Electrophysiology and electropharmacology of the
heart (dogs)
POlHL-1131012 0093 Mechanisms of cardiovascular
disease - Multiple dipole electrocardiogram project (human,
dogs)
POlHL-11310-12 0106 Mechanisms of cardiovascular
disease - Biochemical characterization of the collagens in
vascular tissue (catte)
M POlHL-11414-11 Thrombosis and atherosclerosis program
** POlHL-11678-11 0027 Cardiovascular dynamics and their
control - Vasopressin and thirst in control of body fluid
volumes and osmolality (dogs)
** POlHL-11678-11 0031 Cardiovascular dynamics and their
control - Hypertension caused by stimulation of renal
sympathetic nerves (dogs)
** POlHL-11678-11 0058 Cardiovascular dynamics and their
control - Overall control of the circulation-Computer
analysis
POlHL-11678-11 0059 Cardiovascular dynamics and their
control - Basic hemodynamics (dogs, rats)
** POlHL-11678-11 0065 Cardiovascular dynamics and their
control - Body fluid volumes in the genesis of hypertension
(dogs)
R01HL12415-10 Evaluation of left ventricular function
(dogs, rabbits)
R01HL12493-10 Bioengineering analysis of microvascular
function (cats, rabbits)
R01HL12494-10 Continuum mechanics in biophysics
(human, animals)
** ROlHL-12614-09 Microcirculatory control mechanisms and
hypertension (bats, rats)
R01HL127 11-09 Mathematical approach to cardiovascular
mechanics (human, animals)
P01HL-12738-I0 0065 Physiologic pharmacology and its
clinical applications - Psychotheropeutic drugs and
cardiovascular system (human, rats)
R01HL12766-09 Structure-function relation of blood
vessels (rats, monkeys)
ROlHL-12827-08 Regulation of sodium excretion (dogs,
rats)
M P01HL13262-07 Arterial wall in atherosclerosis
** POlHL-13262-07 0011 Arterial wall in atherosclerosis -
Role of hypertension In atherosclerosis (human, monkey,
dog)
** POlHL-1326207 0024 Arterial wall in atherosclerosis -
Serial ocular changes in arteriosclerosis and hypertension
R01HL13636-08 Effects of pharmacologic agents on heart
metabolism (human, rodents)
ROlHL-1388815 Regulation of respiration
** R01HL-13936-06 Microvascular responses in hypertension
(human, rats)
P50HL1413805 0015 Center for research on
atherosclerosis - Arterial wall-Intermediary metabolism,
enzyme activity and bioenergetics
P50HL-14141-05 0002 SCOR for atherosclerosis in
childhood ■ Intrauterine environment of proband group
(human)
M ROlHL-14148-07 The regional circulations
** R01HL14148-07 0004 The regional circulations -
Funduscopic mapping by photography (human)
** ROlHL-14148-07 0009 The regional circulations •
Myocardial circulation in hypertension and atherosclerosis
(human)
CAR
P50HL-14159-08 Specialized center of research in
hypertension
P50HL14159-08 0008 Specialized center of research in
hypertension - Renal function and sodium metabolism in
hypertension (rats, human, rabbits)
P50HL-14159-08 0018 Specialized center of research in
hypertension - Sympathetic nervous system in hypertension
(rats)
P50HL-14159-08 0023 Specialized center of research in
hypertension - Core computation
P50HL-14159-08 0024 Specialized center of research in
hypertension - Core resources (clinical, animal models)
P50HL 14164-07 0029 A/S SCOR-Comparative and
experimental atherosclerosis - Development of pigeon
substrains
P50HL-14192-08 Specialized center of research in
hypertension
P50HL-14230-07 0088 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Coronary risk factors in school children-
The Muscatine study
P50HL-14236-05 0005 Prevention of premature
arteriosclerosis - Genetically hyperlipidemic and
hypolipidemic rats
P50HL-I423605 0007 Prevention of premature
arteriosclerosis - Exercise stress testing
hyperlipoproteinemia (human)
ROlHL-14378-07 Lipemias and reconstructive cardiac
surgery (human)
P01HL14388-07 Regulation of the circulation In
pathological states
POlHL-14388-07 0155 Regulation of the circulation in
pathological states - Cardiopulmonary afferent activity,
carotid chemo-baroreceptor reflexes
> POlHL-14388-07 0158 Regulation of the circulation in
pathological states - Developmental aspect of abnormal
vascular reactivity (rats)
' POIHL- 14388-07 0159 Regulation of the circulation in
pathological states - Early drug and diet interventions and
blood pressure development (rats)
* POlHL-1438807 0160 Regulation of the circulation in
pathological states - Mechanism of the antihypertensive
effect of training (rats)
POlHL-1438807 0167 Regulation of the circulation in
pathological states - Increased reactivity of artery vascular
muscle in spontaneously hypertensive rat
POlHL-14388-07 0168 Regulation of the circulation in
pathological states - Ionic basis of depolarization (rats,
tissue culture)
* POlHL-14388-07 0178 Regulation of the circulation in
pathological states - Structural and functional
consequences of denervation (rats)
POlHL-14388-07 0179 Regulation of the circulation In
pathological states - Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
POlHL-14388-07 0183 Regulation of the circulation in
pathological states - Vasopressin in cardiovascular
regulation (dogs, rats)
POlHL-14388-07 0185 Regulation of the circulation in
pathological states - Reflex control of venous tone (human,
rabbits, dogs)
POlHL-14388-07 0187 Regulation of the circulation in
pathological states - Histamine and circulatory control
* P01HL14388-07 0193 Regulation of the circulation in
pathological states - Ontogenesis of central nervous system
amines in hypertension (rats)
* POlHL-14388-07 0194 Regulation of the circulation in
pathological states - Dopamine-beta-hydroxylase localization
and release in hypertension
* POlHL-14388-07 0195 Regulation of the circulation in
pathological states - General review of potential
pathophysiologic factors in spontaneous hypertension
* POlHL-14388-07 0196 Regulation of the circulation in
pathological states - Altered vascular responsiveness in
spontaneous hypertension (rats)
'* POlHL-14388-07 0197 Regulation of the circulation in
pathological states - Altered vascular reactivity in
pathogenesis of spontaneous hypertension (rats)
'* POlHL-14388-07 0198 Regulation of the circulation in
pathological states - Humoral factors in vascular reactivity
in spontaneously hypertensive rats
'* POlHL-14388-07 0199 Regulation of the circulation in
pathological states - Adrenergic stimulation in
spontaneously hypertensive rats
'* POlHL-14388-07 0201 Regulation of the circulation in
pathological states - Central sympathetic discharge in
spontaneously hypertensive rats
"* POlHL-14388-07 0202 Regulation of the circulation in
pathological states - Development of hypertension in
spontaneously hypertensive rats
** POlHL-1438807 0203 Regulation of the circulation in
pathological states - Activation of sympathetic nervous
systems in spontaneously hyperactive rats
POlHL-1438807 0204 Regulation of the circulation in
pathological states - Reflex control of vascular resistance
in spontaneously hypertensive rats
** POlHL-14388-07 0205 Regulation of the circulation in
pathological states - Pathogenesis of hypertension in
spontaneously hypertensive rats
** POlHL-1438807 0207 Regulation of the circulation in
pathological states - Brain and reninangiotension
interaction in spontaneous hypertension (rats)
(contd)
'Excludes reutine mdhodokigy OR covers only general projects which preclude indexing at the specific level.
**Onefited significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
CAR
POIHl 14388 O; 0208 R(|ulilion ot th« circulitlon In
pitholo|lcal statts Baroiectplot rellai function In noimal
and hypadanilva man
POIHI 14388 0/ 0209 Regulation ol tha circulation In
patholoilcal itatas Nauial lagulalion ol vasculai
raslstanca In human hyparlension
POIHI 14388 0; 0210 Regulation ol the ciiculalion in
patholoilcal statei Ettects ol dietary sodium on blood
pressure and vascular reactivity
POIHL 14388 0/ 0216 Regulation ol the circulation in
pathological states Development and regression ot
ventricular hypertrophy (cats, rats)
POIHI 1438807 0219 Regulation ol the circulation In
pathological states Myocardial ischemia and infarction In
animals (dogs)
POIHL 14388 07 0222
pathological states -
hypertension (rats)
POIHL 14388 07 0223
pathological states
(rats)
POIHL 1438807 0224
pathological states
(human)
POIHL 1438807 0225
pathological states
99
ROIHI 17366 05 Machanitms In the production of ranal
hypertenMon (lebhlts. dogs)
ROIHI 17401 03 Mechanisins in angiotensin induced
hypertension (cats, dogs)
Regulation ol the circulation in
Renal perfusion pressure in
Regulation of the circulation in
Kallikreinkinin system in hypertension
Regulation of the circulation in
KalliKrein-kinin system in hypertension
Renal vascular reactivity in hypertensive
Regulation of the circulation in
Release of renal prostaglandins by
saluretic-diuretic agents (dogs)
■ ROIHL 1452607 Oral contraceptives and hypertension
(rats)
• ROIHL 1494407
patient
ROIHL 1504706 Digital computer analysis of the
electrocardiogram (human)
■ P50HL1506207 0020 Study of lipoproteins, artery wall.
and atheriisclerosis Artery wall reactions -Elevated
pressure and hyperlipemia (monkey)
P50HL 15103 07 A/S SCOR-Early natural history of
arteriosclerosis
P50HL-I510307 0001 A/S SCOR-Early natural history of
arteriosclerosis • Clinical research-Bogalusa heart study
(children)
' P50HI.-1510307 0013 A/S SCOR-Early natural history of
arteriosclerosis - Experimental models of atherosclerosis
(monkeys)
' ROIHL 15174-06 CV disease epidemiology-Second
generation studies (human)
POlHL-15194-07 0020 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation in
arteriographically normal arteries (human)
R01HL-1S448-06 Surgical and metabolic aspects of
venous grafts, (dogs, monkeys, rabbits)
R01HL-155e2-05 Regulation of skeletal muscle blood flow
(dogs)
ROlHL-15696-06 Mechanism and role of cyclic GMP in
heart (animals)
POlHL-15832-06 0007 Chemical-structural predispositions
to lung injury - Inactivation of vasoactive agents by the
lung (human, rats, cats, dogs)
ROlHL-15852-06 Vascular ion transport and hypertensive
mechanisms
ROIHL- 16003-08 Sources and roles of calcium in smooth
muscle excitation (rats)
ROlHL-16037-06 Molecular properties of cardiac
adrenergic receptors
ROlHL-16076-06 Electrophysiology ot fibrillation and
defibrillation (human)
ROlHL-1631505 Analysis of interaction between CNS
vasomotor systems (cats, rats)
ROlHL-16328-06 Membrane electrical properties of
vascular muscle (human, animals)
ROlHL-16403-05 Prognostication by computer-Analyzed
vectorcardiogram (human)
ROlHL-16419-03 Arterial uptake of lipoprotein-Kinetic
analysis (rabbits)
ROlHL-16454-03 Vascular muscle reactivity in
hypertension (human, rats)
ROlHL-16648-16 Integrated control of cardiovascular
activity (cats)
ROlHL-16657-06
(rats)
ROIHL-16774-04
(Honolulu)
P01HL16910-05 0005 Regulation of the peripheral
circulation - Control of circulation by baroreceptor and
chemoreceptor reflexes (dog, monkey)
ROIHL- 16952-05 Cardiovascular pathology (rats, rabbits)
R25HL170560! Improving patient compliance through
nursing action
P60HL- 1726904 0023 National heart and blood vessel
research and demonstration center - Cardiovascular
pharmacology-Ischemia, shock and heart failure (dog, cat,
rat)
P60HL- 17269-04 0024 National heart and blood vessel
research and demonstration center - Section of
experimental cardiovascular surgery-Core facility
P60HL- 17269-04 0039 National heart and blood vessel
research and demonstration center - Health care services
to patients in neighborhood clinics
ROIHL-17335-05 Contractile properties of hypertensive
arterioles (rats)
ROIHL-17341-03 Practical total synthesis of
prostaglandins
Innervation of coronary arteries and heart
Genetic epidemiology of hyperlipemia
ROIHL 17580 04
disease (men)
ROIHL 17604 03
recording system
ROIHL 1770504
The Impact of stress on coronary heart
Wearable blood pressure and ECG
Hemodynamics in curved arteries
Drug taking for hypertension in a rural
Pathogenesis and complications of
Kallikrein kinin system in hypertension
(human, rats, dogs)
•• ROIHL 1770604 Psychosocial hypertension,
catecholamines and drugs (mice)
** ROIHL 1772403 Oral contraceptives and hypertension
(rats)
ROIHL 17747 04 Endothelial injury and regeneration (rats)
'* ROIHL 1774903 Adrenocortical factors in human
hypertension (human)
** ROIHL 1775403 Pathogenesis and prevention of
hypertension sequelae (rats)
ROIHL 17781 03 Hypertension, kidney disease and renal
lymph (dogs, rats)
M POIHL 17871 04 Kidney, sodium, cardiac output, arterioles
and hypertension
ROIHL 17897 03 Synthesis of alpha and beta adrenergic
antagonists
** ROIHL 18027-03 New vasoactive factors and their role in
hypertension (human, dogs, rats)
ROIHI 18077 04 Smooth muscle cell organization and
Ca20 concentration control (chickens)
ROlHL-18085-03 Neural factors in atherogenesis (squirrel
monkeys)
** ROlHL-18087 03 Development and regression of cardiac
hypertrophy (rats, rabbits)
R01HL-I8095-04 Human dopa mine-beta hydroxylase (also
cattle)
ROlHL-181 56-02
** ROlHL-181 75-03
community
M P50HL- 183 18-03
hypertension
** P50HL-18318-03 0001 Pathogenesis and complications of
hypertension Core clinical program
** P50HL-183 18-03 0002 Pathogenesis and complications of
hypertension - Core experimental animal facility (rats,
rabbits)
** P50HL-183 18-03 0003 Pathogenesis and complications of
hypertension - Core biochemical laboratory
** P50HL-183 18-03 0007 Pathogenesis and complications of
hypertension - Humoral factors and renal function in
experimental hypertension (rats)
** P50HL-183 18-03 0012 Pathogenesis and complications of
hypertension - Behavioral factors in hypertension (human)
** P50HL-183 18-03 0013 Pathogenesis and complications of
hypertension Humoral factors and renal function in
human hypertension
** P50HL-183 18-03 0014 Pathogenesis and complications of
hypertension - Arterial metabolism and atherogenesis (rat,
rabbit)
" P50HL-183 18-03 0015 Pathogenesis and complications of
hypertension - Cultured smooth muscle cells and
microvessel metabolism (mammals)
** P50HL-183 18-03 0018 Pathogenesis and complications of
hypertension - Plasma renin activity in chronic ischemic
heart disease (human)
** P50HL-183 18-03 0019 Pathogenesis and complications of
hypertension - Renin-angiotensin system in blood pressure
regulation (human, rat, dog)
M P50HL-18323-04 SCOR hypertension center
** P50HL-18323-04 0011 SCOR hypertension center -
Endocrine profiling on a selected normal population
(human)
** P50HL-18323-04 0012 SCOR hypertension center
as a risk factor (human)
** P50HL-18323-04 0033 SCOR hypertension center
laboratory-Renin, aldosterone and bradykinin methodology
** P50HL-18323-04 0034 SCOR hypertension center - Core-
Data management
** P50HL-18323-04 0035 SCOR hypertension center - Control
of high blood pressure at the worii site
** P50HL-18323-04 0038 SCOR hypertension center -
Unknown adrenocortical mechanisms in hypertension
(human)
" P50HL- 183 23-04 0041 SCOR hypertension center -
Measurement of sympathetic response in hypertensive
patients
** P50HL-18323-04 0042 SCOR hypertension center - Blood
viscosity and blood volume in hypertensive disease
(human, dog)
** P50HL-18323-04 0043 SCOR hypertension center -
Pharmacology-Renin-aldosterone mechanisms in essential
hypertension (human)
** P50HL-18323-04 0044 SCOR hypertension center -
Angiotensin blockade to identify angiotensin II factor in
hypertension (human)
** P50HL-18323-04 0045 SCOR hypertension center -
Laboratory programs-Prorenin (human)
** P50HL-18323-04 0046 SCOR hypertension center -
Coronary artery bypass surgery-Associated hypertension
(human)
** P50HL 1832304 0047 SCOR hypertension center -
Transcendental meditation and self-hypnosis-Hypertension
treatment (human)
Renin
Core
Cardiovascular follow up of hyptrtantiva
Genesis of atherosclerotic letiont
Hemodynamic interactions of vasoactive
Radioimmunoassay of angioteniinogen
Indirect mean arterial pressure
Experimental neurogenic hypertension
Experimental neurogenic
Model of sustained arterial
•Ettkides rwjtine methodotogy OR covers only general projects which preclude indexing at the specific level.
"Onenled significantly to above subject.
M Grant^as subprojects describing specific research aspects.
See Appendix for investigator's name and grant number
CAR
R2SH1 18406 03 Adhiitnct to hypaftonilvt mtdtcil
legimem (liumin)
R25HI 18414 03 Hypertuniion (amlly >lrtl*|l« Im
patient adherence
R75HL 18418 03 Role of • supporting partner in
adherence (human)
R25HI 18424 03 Blood presiui* education in an indutlrial
■jetting (human)
ROIHL 18456 03
adolescents
ROIHL 18473 04
(human, mules)
ROIHL 18489 03
chemicals (rats)
ROIHL 18561 03
(human)
POIHL 18574 03 0001 Lipoprotein methodology and
biomedical applications Ultracentrifugal and
electrophoretic lipoprotein methodology Applications
** ROIHL 1862904 Influence of aging and hypertension on
the myocardium (rats)
" ROIHL 1873003 Role of mineralocorticoids in low renin
hypertension (human, rats)
ROIHL 18783 04 Detection and control of ventricular
premature beats (human)
"* ROIHL 18814 03 Behavioral tactics for clinical cardiac
control (human)
** ROIHL 18823-02 Physiological correlates of conditioned
blood pressure (human)
** ROIHL 1883103 Microscopy of spontaneously hypertensive
arterial lesion (rats)
ROIHL 18850-03 Classification code for Frank orthogonal
ECG
ROIHL- 18866-02 Microvascular flow, volume, and
reactivity (rats, cats)
ROIHL 18933 03 Energy output and efficiency of left
ventricle (dog)
ROlHL-18947 02
(mammals)
M POlHL-18974-03
program
** POlHL-18974-03 0006
hypertension program
hypertension (cats)
" ROlHL-18976-03 Blood pressure control -Relation to
behavioral stress (human, dog)
** R01HL19027-03 Calcium and cyclic AMP in causation of
hypertension (rats)
** ROlHL-19048-03 Structure of baroreceptors in
hypertension (rats)
ROIHL 19057-03 Catecholamines and cyclic AMP in
cardiovascular system (rats, dogs)
** ROlHL-19091-02 Sustained increase in cardiac output
(dogs)
** ROIHL- 19 144-03 Contraceptive steroids and experimental
hypertension (rats)
" ROlHL-19226-03 Vascular smooth muscle in hypertension
(rats)
M POIHL 19242-02 Study of vascular smooth muscle
" POIHL- 19242-02 0001 Study of vascular smooth muscle -
Energy metabolism and protein turnover in vascular smooth
muscle (rats)
" POlHL-19242-02 0002 Study of vascular smooth muscle -
Vascular smooth muscle response to serum lipoproteins
(rats)
** POlHL-19242-02 0003 Study of vascular smooth muscle -
Vasoactive metabolites from vascular muscle and
parenchymal tissue (animal)
•* POIHL 19242-02 0006 Study of vascular smooth muscle -
The contractile system of vascular smooth muscle (swine,
rats)
** POlHL-19242-02 0007 Study of vascular smooth muscle -
NE release in and reactivity of vascular smooth muscle
(animals)
** POlHL-19242-02 0008 Study of vascular smooth muscle -
NE release in and reactivity of vascular smooth muscle
(rats)
** POlHL-19242-02 0009 Study of vascular smooth muscle -
Electrophysiology of vascular smooth muscle (rats, chick
embryo)
ROlHL-19246-03 Regression of cardiac hypertrophy-
Myocardial and renal (human)
** ROlHL-19287-03 The antihypertensive function of the
renal medulla (human, rats, rabbits)
M P50HL- 19362-02 A/S SCOR-Atherosclerosis in nonhuman
primates
P50HL-19362-02 0003 A/S SCOR-Atherosclerosis in
nonhuman primates Heritability of characters related to
atherosclerosis (baboons)
P50HL 19362 02 0004 VS SCOR-Atherosclerosis in
nonhuman primates - Selective breeding for characters
related to atherosclerosis (baboons)
" P50HL-19362-02 0011 A/S SCOR-Atherosclerosis in
nonhuman primates - Chronic hypertension induced by
operant conditioning techniques (baboon)
** P50HL-19362-02 0012 A/S SCOR-Atherosclerosis in
nonhuman primates - Induction of chronic hypertension by
salt loading (baboon)
ROlHL-19394-03 Biochemistry and regulation of taurine in
the heart (rats, guinea pigs, cats)
** ROlHL-19568-03 Hypertension-Analysis of drug and
behavioral therapies (human)
(contd)
CAR
ROlHL-19839-09 Factors in youth predisposing to ctironic
diseases (former college students)
ROlHL-19844-02 Behavioral control of essential
hypertension (human)
ROlHL-19858-03 UMMC-Blood pressure precursors and
consequences (human)
R01HL19877-02 Prevention of high blood pressure in
children
ROlHL-19997-02 Prostaglandin precursors and intestinal
vasculature (cats, rabbits)
ROlHL-20054-02 Cultured blood vessel cells--
Pathophysiology (human, animals)
ROlHL-20124-02 Coronary risk factors (human)
ROlHL-20179-02 Epidemiology of sudden cardiac death
among women
ROlHL-20187-01 Evaluation of exercise cardiac
rehabilitation program (40-55 year old men)
ROlHL-20201-01
receptors (rats)
ROlHL-20244-02
ROlHL-20245-01
ROlHL-20247-01
ROlHL-20248-01
ROlHL-20339-02
Hypertension and vascular steroid
he impact of hypertension information
The impact of hypertension information
The impact of hypertension information
The impact of hypertension information
Vascular alpha-adrenergic receptor
molecular properties
ROlHL-20364-01 Episodic hypertension associated with
human behavior (air traffic controllers)
ROlHL-20455-03 Role of systemic hypertension on diabetic
retinopathy (human)
ROlHL-20471-03 Atherosclerosis and diabetes mellitus
(human)
ROlHL-20542-03 Regional hemodynamics in spontaneous
hypertension (rats)
POlHL-20552-02 The development and regression of
cardiac hypertrophy
POlHL-20552-02 0002 The development and regression of
cardiac hypertrophy - Effect of treatment on the
hypertrophied left ventricle (rats)
POlHL-20552-02 0003 The development and regression of
cardiac hypertrophy - Muscle mechanics of the
hypertrophied left ventricle (rats)
ROlHL-20572-02 Hemodynamic relations to metabolism in
hypertension
ROlHL-20572-02 0001 Hemodynamic relations to
metabolism in hypertension - Hemodynamic and myocardial
functional studies in the SHR (rat)
ROlHL-20572-02 0003 Hemodynamic relations to
metabolism in hypertension - Cardiac output and organ
blood flow in hypertension (rats)
ROlHL-20572-02 0008 Hemodynamic relations to
metabolism in hypertension - Role of nervous system in
hemodynamic function
POlHL-20581-01 Vascular neuroeffector mechanisms in
health and disease
POlHL-20581-01 0005 Vascular neuroeffector
mechanisms in health and disease - Changes in the
neuroeffector mechanism in hypertension (rabbits)
POlHL-20581-01 0006 Vascular neuroeffector
mechanisms in health and disease - Neuroeffector
mechanism in arteries and veins in hypertension (human)
ROlHL-20604-03 Sympathectomy-Cardiovascular and
molecular pharmacology (animals)
ROlHL-20655-02 Autonomic predictors of hypertension in
children
ROlHL-20662-02 Physical activity, fitness and
epidemiology of CHO
ROlHL-20678-02 Cardiovascular adaptation to stress in
disease states (dogs)
ROlHL-20724-01 Behavioral consequences of hypertension
(human)
ROlHL-20827-02 Effects of hypertrophy on the coronary
circulation (dogs)
ROlHL-20895-03 0001 Cineangiographic studies of
cardiovascular system - Videodensitometry and valvular
regurgitation (human, dogs)
ROlHL-20910-02 The alternative diet for coronary disease
prevention (human)
ROlHL-21010-02 Glycemia, other traits and CV death in
40,000 persons
R01HL-21030-0I
(rats)
R23HL-21066-02
aldosterone (rats)
ROlHL-21088-02 Genetic patterns in deaths from Ml and
stroke in Utah
ROlHL-21099-02 Subcellular changes of blood vessels in
hypertension (rats)
ROIHL 21245-02 Influence of chronic exercise on
hypertension (rats, primates)
ROlHL-21260-02 Risk factor relationships of
atherosclerosis (monkeys)
ROlHL-21274-01 Prorenin-Physiological and biochemical
analysis (human)
R23HL-21291-02 Renin-mineraiocorticoid axis in
hypertensive diabetics (human)
ROlHL-21418-02 Experimental myocardial infarction (rats)
ROlHL-21427-02 Behavioral changes m post infarction
patients
ROlHL-2 1429-02
mammals)
■ ROlHL-2 1498-02
Calcium regulation and hypertension
Angiotensin and prostaglandin control of
Transport of LDL in arterial wall (human.
Pathophysiology of edema (rats, cats)
100
ROlHL-21523-01 Hemodynamic effects of dietary sodium
in man
ROlHL-21525-02 Effect of cations, anions and water upon
blood vessels (dogs, rats)
ROlHL-21532-02 Cardiovascular homeostasis and learning
(frogs, rats, human)
ROlHL-2 15 78-01 Effect of exercise upon the hypertensive
adolescent
ROlHL-2167301 Pathophysiology of venous changes in
hypertension (rats, rabbits, human, dogs)
ROlHL-21756-11 Vascular disease-Cytochemistry and
ultrastructure (human, rats, mice, hamsters)
ROlHL-21799-01 Circumventricular sites of pressor action
of angiotensin II (rats)
ROlHL-22032-01
(human)
ROlHL-222 12-01
control program
ROlHL-22264-01
Cardiovascular events in hypertensives
Alameda county high blood pressure
Regulation of contraction in vascular
smooth muscle (dogs)
Autonomic mechanisms in man
Origins of hypertension (human)
Pathogenesis of atherosclerosis in rats
Regulation of cardiac adaptation to
ROlHL-22296-01
ROlHL-222 98-02
ROlHL-22341-01
ROlHL-22361-01
exercise (rats)
ROlHL-22378-01 Psyco-somatic predictors of CHD in
adolescence (human)
ROlHL-22380-01 Detroit hypertension control program
ROlHL-22506-01 Hemodynamics of the clinical
hypertensions
ROlHL-22512-01 Ultrasonic instrumentation for
cardiovascular studies
ROlHL-22546-02 Baroreceptor reflex mechanisms in man
R01HL-226G301 Trace metals, vascular activity and
hypertension (rats)
POlHL-226 19-01 0010 Cellular mechanisms of heart
failure ■ Mitochondria in heart and smooth muscle (rabbits,
rats, dogs)
ROlHL-2266701 Mechanisms of baroreceptor adaptation
in hypertension (dogs)
ROlHL-22740-01 Behavior and cardiovascular disease -
Basic mechanisms (human)
ROlHL-22750-01 Digoxin in heart failure with sinus
rhythm (human)
' ROlHL-22802-01 A rural mining community hypertension
control project (human)
' ROlHL-22836-01 The spontaneously hypertensive kidney
(rats)
ROlHL-22854-01 Non-invasive blood pressure
measurement (rats)
' ROlHL-2286801 Presynaptic regulatory mechanisms in
hypertension (rats, dogs)
' ROlHL-22873-01 Adrenoceptor interconversion and
hormone homeostasis
' ROlHL-22939-01 Human kinin and fibrinolytic systems
and renal disease (human)
ROlHL-22946-01 Prostaglandins, platelet aggregation and
vasoactivity (human, rats, rabbits)
* R23HL-22984-01 Cyclic AMP dependent protein kinases in
hypertension (rat)
• ROlHL-231 15-01
(frogs, rats)
Regulation of active sodium transport
Mechanisms of hypertension (human.
ROlHL-23201-01
rats)
ROlHL-233 12-01 Hemodynamics and vasoactivity in renal
hypertension (human, dogs)
ROlHL-23600-01 Ions, water, and hypertension (human,
dogs, rats)
ROlHL-23602-01 Physiology of renin, aldosterone and
prostaglandin (human, rats, dogs)
NOlHV-12434-11 Therapy for hypertension in the general
population
NOlHV-12435 15 Therapy for hypertension in the general
population (human)
NOlHV-12436-15 Hypertension therapy in the general
population (human)
N01HV1244014 Therapy for hypertension in the general
population (human)
NOlHV-12442 14 Therapy for hypertension in the general
population (human)
NOlHV-2293114 Therapy for hypertension in general
population
NOlHV-22937-07
population
NOlHV-22938-11
population
NOlHV-22939-12
program center
NOlHV-22945-11 Cooperative hypertension detection and
follow-up study (human)
NOlHV-22971-07 Prevention of coronary heart disease
(human)
NOlHV-2297607 Multiple risk factor intervention trial,
prevention of coronary heart disease
NOlHV-22977-08 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22979-07 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22980-06 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22981-10 Intervention trial for the prevention of
coronary heart disease (human)
Therapy for hypertension in general
Therapy for hypertension in general
Hypertension detection and follow-up
CAR
NOlHV-22982-07 Intervention trial for prevention of
coronary heart disease (human)
NOlHV-22983-07 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-32933-07 Hypertension detection and follovi-up
program central laboratory (human)
NOlHV-33101-06 Development and conduct of a multiple
risk factor intervention trial (human)
NOlHV-33105-09 Intervention trial for prevention of
coronary heart disease (human)
NOlHV-33106-06 Intervention trial for the prevention of
coronary heart disease (human)
NO lHV-33 108-04 Prevention of coronary heart disease
(human)
NO lHV-33 109-04 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-331 10-04 Prevention of coronary heart disease
(human)
NOlHV-42929-08 Risk factor intervention trial for the
prevention of CHD (human)
NOlHV-42932-05 Risk factor intervention trial for the
prevention of CHD (human)
NOlHV-42933-09
disease (human)
Multiple risk factors in coronary heart
Nonhuman primate models of
NOlHV-53029-04
atherosclerosis
NOlHV-5303005 Nonhuman primate models of
atherosclerosis and hypertension
NOlHV-53031-04 Nonhuman primate models of
atherosclerosis and hypertension
NOlHV-62905-02
arteriosclerosis
NOlHV-72915-02
population
NOlHV-72978-02
NOlHV-72980-02
NClHV-7298403
(human)
NOlHV-72986-02
(human)
NOlHV-72987-02
(human)
NOlHV-72989-02
(human)
NO1HV-72990-00
(human)
NOlHV-82913-00
Non-human primate models of
Therapy for hypertension in the general
Development of models of hypertension
Development of models of hypertension
High blood pressure control program
High blood pressure control program
High blood pressure control program
High blood pressure control program
High blood pressure control program
Demonstration programs in hypertension
control in the work setting (human)
" NOlHV-82915-01 Therapy for hypertension in the general
population (human)
CARDIOVASCULAR DISORDERS, HYPERTENSION
(SYSTEMIC), ANGIOTENSIN-RENIN-
ALDOSTERONE-ASSOCIATED
SEE ALSO METABOLIC DISORDERS INBORN, BARHER'S
SYNDROME
SEE ALSO PEPTIDES, VASOACTIVE PEPTIDES, ANGIOTENSIN
SEE ALSO PEPTIDES, VASOACTIVE PEPTIDES, ANGIOTENSIN II
SEE ALSO PEPTIDES, VASOACTIVE PEPTIDES,
ANGIOTENSINOGEN
SEE ALSO PEPTIDES, VASOACTIVE PEPTIDES, RENIN
SEE ALSO PEPTIDES, VASOACTIVE PEPTIDES, RENIN-
ANGIOTENSIN SYSTEM
SEE ALSO PROTEASES AND PEPTIDASES, ANGIOTENSINASE
** ROlHL-01015-27 Hypertension and left ventricular
hypertrophy (dogs)
ROlHL-03303-21 Factors regulating electrolyte excretion by
the kidney (human, dogs)
ROlHL-03341-22 Epidemiology of atherosclerosis in Evans
Co Georgia
** POlHL-06835-17 0017 Cardiovascular disease - Studies
on obese hypertensive rats
** POlHL-06835-17 0037 Cardiovascular disease - Cardiac
hypertrophy in spontaneously hypertensive rat
** POlHL-06835-17 0045 Cardiovascular disease - Pressure-
volume-renin relationship in human hypertension
** ROlHL-06975-18 Pathogenesis and prevention of
hypertension (rats)
POlHL-08682-15 0005 Regulation of the cardiovascular
system - Smooth muscle and mechanical properties of
blood vessels (dogs, human)
** ROIHL-09154-14 Central control of distribution of organ
blood flow (monkeys)
** ROlHL-0991112 Hormonal and dietary modification of
NaCl toxicity (rats) mice)
ROlHL-10612-13 Humoral factors in heart failure and
hypertension
ROlHL-1 1046-12 Renin, angiotensin, steroids, ions and
blood pressure (human, sheep, rabbits)
P01HL11414-11 0014 Thrombosis and atherosclerosis
program - Role of adrenal in human essential hypertension
P01HL-11678-1I Cardiovascular dynamics and their
control
ROlHL-12684-09 Angiotensin I and converting enzyme in
hypertension (human, primates, dogs)
ROlHL-13595-08 Renin and vascular hyper-reactivity in
hypertension (human, rats)
ROlHL-13917-20 Secretion and effects of adrenal
hormones (human, rabbits, sheep)
ROlHL-1414807 0002 The regional circulations -
Catecholamine metabolism in subtypes of hypertension
(human, animals)
(contd)
M
M
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level
'•Oriented significantly to above subject.
U Grant has subprojeds describing specific research aspects.
See Appendix for investigator's name and grant number.
CAR
101
CAR
ROINl 14148 07 0008 The itglonal circulttlont - Rinal
circulation in hyp«rtensive patients (also doll)
PbOHl I41b9 08 0020 Spacialind center of research m
hypertanjion Renin minerilocorticoid system in
hypertension (human, ral. do|)
P60HL 141!i9 08 0022 Spacialiied center ol research in
hypertension Core litMratofy
M PbOHL 14192 08 Speciahied center ot research in
hypertension
PSOHl 14192 08 0003 Specialiied center ol research in
hypertension Prostaglandins as mediators ol renin
secretion (human, dog)
PbOHL 14192 08 0004 Specialized center ol research in
hypertension Isolation and characteruatlon ol pure renin
(swine, rats, human, rabhits)
P50HL 14192 08 OOOS Specialized center ol research in
hypertension New techniques tor recognition ot
renovascular hypertension (human, dogs)
P50HL 14192 08 0007 Specialized center ot research in
hypertension Role ol new mmeralocorticoids in
hypertension (human, rats)
ROIHL 14306 07 Quantilication ol arterial pressure control
(dogs)
ROIHL 1439707 Hypertension Angiotensin and
prostaglandin pharmacology (animals)
R01HL'14S09'07 Hypertension- Chemistry and biophysics
ot angiotensin
ROlHL'14560-07 Hypertension produced by sympathetic
dyslunction (human, rats)
ROIHL 1494407 Renal vascular reactivity in hypertensive
patient
ROIHL' 15307-06 Central nervous control ot renin and
blood pressure (dogs)
ROlHL-15528-05 Renin kinetics in hypertensive and
uremic plasma (human, dogs)
ROlHL-15808-06 Role ol angiotensinogen in hypertension
and stroke (human, rabbits)
ROlHL-15837-06 Renin and cardiac hypertrophy in
hypertension (rats)
R01HL-16603-05 Human and experimental renal diseases
(animals)
* ROlHL-16918-05 Role ol steroids in hypertension (human)
* ROlHL-17243-05 Cause ol chronic experimental renal
hypertension (dogs, rabbits)
* ROlHL-17364-04 'Big renin'-Biochemical and clinical
studies (human)
ROlHL-17458-04 Renal control ol sodium excretion (rats)
ROIHL-1 7487-04 Adrenergic-vasoregulation interactions in
hypertension (human)
ROlHL-1 7706-04 Psychosocial hypertension.
catecholamines and drugs (mice)
ROlHL-17947-04 Experimental renal and neurogenic
hypertension (human, animals)
ROlHL-17958-04 Circulatory etiects of operant
cardiovascular control (baboons)
ROlHL-18102-02 Role ol the adrenal cortex in human
hypertension
M P50HL-18318-03 Pathogenesis and complications of
hypertension
P50HL-18318-03 0001 Pathogenesis and complications of
hypertension - Core clinical program
" P50HL-183 18-03 0004 Pathogenesis and complications of
hypertension - Steroid and renin profiles in hypertension
(rats, human)
** P50HL-18318-03 0009 Pathogenesis and complications of
hypertension - The mineralocorticoid-hypertensive syndrome
in man
** P50HL-18318-03 0010 Pathogenesis and complications of
hypertension - Hemodynamics in mineralocorticoid and low
renin hypertension (human)
** P50HL-18318-03 0011 Pathogenesis and complications of
hypertension - Adrenergic function-Rcnin and
mineralocorticoid activity (human)
** P50HL-18318-03 0019 Pathogenesis and complications of
hypertension - Renin-angiotensin system in blood pressure
regulation (human, rat. dog)
ROlHL-18624-03 Study of kinins in hypertension and other
diseases (human)
** ROlHL-18875-03 Angiolension, prostaglandins, pressure
and the kidney (rats)
** ROlHL-18882-02 Hormones in hypertension (human)
*' ROlHL-1889102 Electrolyte intake and blood pressure in
hypertension (human)
" ROlHL-19012-03 Smooth muscle of resistance vessels in
hypertension (rats)
" ROlHL-19229-02 Prostaglandins and hypertension (human.
rats, dogs, rabbits)
** R01HL-I9279-03 Intracellular action of aldosterone in
hypertension (human, rats)
ROlHL-19320-03 Angiotensin neuropharmacology-
Relationship to sodium
** P50HL-19362-02 0010 A/S SCOR-Atherosclerosis in
nonhuman primates - Antihypertensive therapy-
Atherogenesis in experimental hypertension (baboon)
** ROlHL-19428-03 Role of angiotensin sensitivity in renin
release (human)
ROlHL-19538-03 Synthesis of potential antihypertensive
agents
** ROlHL-19644-03 Etiological factors in hypertension
(human, dogs, rats)
** ROlHL-20189-01 Effects of renin on atherogenesis
(rabbits)
ROIHl 202 78 02 Ctllulir mtchinlimi of ranin iicrdlon
(rats)
POIHI ^0')8I 01 0006 Viiculir niuiMllecloi
mKihanisms in health and diieasa - Niuroellector
mechanism in arteries and velni In hypertension (human)
ROIHL 21112 02 Aldosterone binding, clearance, and
secretion in man
ROIHL 216 73 01 Pathophysiology ol venous changes in
hypertension (rats, rabbits, humiin. dogs)
ROIHL 2177901 Steroids in adional regeneration
hypertension (rats)
ROIHL 218!>1 01 Cerebral microcirculation in experimental
hypertension (cats, rabbits)
Iso renins in the hypertensive rat
Blood volume distribution in hypertension
Hypertension, microvascular control and
Studies ol vasomotor control (rats)
Adrenal steroids in adolescent and adult
Experimental renal arterial hypertension
ROIHL 2187701
ROIHL 21893 01
(human)
R23HL2190101
exercise (rats)
R23HL 21914-01
R23HL 2191701
hypertension
ROIHL 22069-02
(dogs)
ROIHL 22261-01 Compliance ol lluid spaces in advancing
hypertension (rats)
ROIHL 2228801 Renin and precursors- Structure and
tunction (mice)
ROIHL 22390 01 Elfect ol chloride on renin (rats, dogs)
ROIHL 224 11 01 Neuroendocrine involvement in
hypertension (rats)
R23HL 22438-01
(rats)
ROlHL-22506 01
hypertensions
ROlHL-22617-01
(sheep)
R23HL-22728-01
R01HL-23602-01
The etiology ol genetic hypertension
Hemodynamics ol the clinical
Angiotensin, hypertension and the CNS
Neural control ol renin secretion (dogs)
Physiology of renin, aldosterone and
prostaglandin (human, rats, dogs)
** ROIHL 23603-01 Morphogenesis ol hypertensive vascular
disease (rats)
CARDIOVASCULAR DISORDERS, HYPERTENSION
(SYSTEMIC), CATECHOLAMINE-ASSOCIATED
SEE ALSO PHENYLALKYLAMINES, CATECHOLAMINES
** R01HL-I2648-09 Catecholamine metabolism in
hypertensive diseases (human)
** ROlHL-14148-07 0002 The regional circulations -
Catecholamine metabolism in subtypes of hypertension
(human, animals)
** ROlHL-17487-04 Adrenergic-vasoregulation interactions in
hypertension (human)
P50HL-17667-04 0031 Study of ischemic heart disease -
Pathophysiology in ischemic heart disease (dog, cat, rabbit,
monkey)
ROlHL-17958-04 Circulatory efteds of operant
cardiovascular control (baboons)
P50HL-183 18-03 0001 Pathogenesis and complications of
hypertension - Core clinical program
** ROlHL-19644-03 Etiological factors in hypertension
(human, dogs, rats)
** ROIHL-21817-01 Catecholamines, blood pressure and
circulation
** ROlHL-22306-01 Renal catecholamines- Pathophysiology
of hypertension (dogs)
** ROlHL-22506-01 Hemodynamics of the clinical
hypertensions
CARDIOVASCULAR DISORDERS, HYPERTENSION
(SYSTEMIC), ENVIRONMENT-ASSOCIATED
P50HL-141 59-08 0021 Specialized center of research in
hypertension Genetic studies of the physiology of
hypertension (human, rats)
** ROlHL-19204-03 Environmental factors in hypertension
(Rhesus monkeys)
** R01HL-19859-03 Epidemiological studies, precursors of
hypertension (human)
ROlHL-19864-03 Blood pressure of children and young
adults
ROlHL-19864-03 0001 Blood pressure of children and
young adults - Follow up of students from Dormont,
Pennsylvania
ROlHL-19864-03 0003 Blood pressure of children and
young adults - Heart rate and blood pressure -Consistency
in infancy (human)
ROlHL-19869-03 Antecedents of adolescent hypertension
(human)
ROlHL-19922-03 Childhood determinants of blood pressure
ROlHL-19929-03 High blood pressure in the young,
prevalence and precursors (human)
ROlHL-19930-03
newborn twins
ROIHL 19956-03
M
A prospective study-Blood pressure in
High blood pressure in the young
High blood pressure In young people in
(human)
ROlHL-19962-03
Tecumseh
ROlHL-19984-02 Blood pressure and immunogenetic
factors in the young (human)
ROlHL-20005-03 Factors in blood pressure levels of
children
ROlHL-20034-03 Hypertension-Psychophysiologic and
genetic precursors (human)
HOIMI 20159 03 Cantllc tpldtmiolofy of pracurtoft ol
hypitrlfinkion (human)
CARDIOVASCULAR DISORDERS, HYPERTENSION
(SYSTEMIC), GENETICS-ASSOCIATED
ROIHl 01)41 22 tpidi-miolijjy ol ,t<lmir.(tei(i:r. m l»«n-.
Co Ceurgia
" ROIMI 10942 09 Study ol genetic hyparlention in rati
" KOIHl 13408 0b Environmental gantllc intaraclM>n> in
hypertension (rats)
PbOHL I4lb9 08 0020 Specialized center of research in
hypertension Renin niiner;ilocor1icoid system in
hypertension (human, rat. dog)
" P50HU41b9 08 0021 Specialized center of research in
hypertension Cr'netic studies ol the physiology of
hypertension (human, rats)
" ROIHI 1871502 Hypertension incidence proiect (human)
" ROIHI 1985903 Epidemiological studies, precursors ol
hypertension (human)
M ROIHL 19864 03 Blood pressure ol children and young
adults
** ROIHL 19864 03 0001 Blood pressure of children and
young adults Follow up ol students from Dormont.
Pennsylvania
** ROIHL 19864 03 0003 Blood pressure of children and
young adults Heart rate and blood pressure-Consistency
in inlancy (human)
** ROIHL 19869 03 Antecedents of adolescent hypertension
(human)
** ROIHL 19870-03 Hypertensive progeny- Physical and
humoral precursor search
*• ROIHL 19922 03 Childhood determinants ol blood pressure
** ROIHL 19929 03 High blood pressure in the young.
prevalence and precursors (human)
•* ROlHL-19930-03
newborn twins
** ROlHL-19956-03
A prospective study Blood pressure in
High blood pressure in the young
High blood pressure in young people m
'Excludes routine methodotogy OR covers only general projects which preclude indexing at the specific level.
"Onented significanthi to above subject
(human)
** ROIHL 19962-03
Tecumseh
" ROIHL-19984 02 Blood pressure and immunogenetic
factors in the young (human)
** ROlHL-20005-03 Factors in blood pressure levels of
children
** ROlHL-20034-03 Hypertension-Psychophysiologic and
genetic precursors (human)
** R01HL-20159-03 Genetic epidemiology of precursors of
hypertension (human)
** ROlHL-23194-02 Genetics of hypertension and associated
variables (human)
ROlHL-23603-01 Morphogenesis of hypertensive vascular
disease (rats)
CARDIOVASCULAR DISORDERS, HYPERTENSION
(SYSTEMIC), KININS-BRADYKININ-KALLIKREIN-
ASSOCIATED
SEE ALSO PEPTIDES. VASOACTIVE PEPTIDES. KALLIDIN
SEE ALSO PEPTIDES, VASOACTIVE PEPTIDES, KALLIDIN 9
SEE ALSO PEPTIDES, VASOACTIVE PEPTIDES, KALLIKREIN
" ROlHL-09911-12 Hormonal and dietary modification of
NaCl toxicity (rats) mice)
ROlHL-12684-09 Angiotensin I and converting enzyme in
hypertension (human, primates, dogs)
** ROlHL-17705-04 Kallikrein-kinin system in hypertension
(human, rats, dogs)
" ROlHL-18624-03 Study of kinms in hypertension and other
diseases (human)
** ROlHL-18882-02 Hormones in hypertension (human)
CARDIOVASCULAR DISORDERS, HYPERTENSION
(SYSTEMIC), NEUROGENIC HYPERTENSION
ROlHL-01015-27 Hypertension and left ventricular
hypertrophy (dogs)
** POlHL-06835-17 0044 Cardiovascular disease
Baroreceptors in control of blood pressure during sleep
(dogs)
POlHL-11678-11 0031 Cardiovascular dynamics and their
control - Hypertension caused by stimulation of renal
sympathetic nerves (dogs)
** POIHL 11678-11 0069 Cardiovascular dynamics and their
control - Nervous control of the cirulation (dogs)
** P50HL-14159-08 0018 Specialized center of research in
hypertension - Sympathetic nervous system in hypertension
(rats)
** POlHL-14388-07 0186 Regulation of the circulation in
pathological states - Angiotension in modulation of
neurogenic vasoconstriction
** ROlHL-14560-07 Hypertension produced by sympathetic
dysfunction (human, rats)
ROlHL-15307-06 Central nervous control of renin and
blood pressure (dogs)
** ROlHL-16056-05 Studies on neurogenic control of the
circulation (human, dogs)
ROlHL-16315-05 Analysis of interaction between CNS
vasomotor systems (cats, rats)
ROlHL-16657-06 Innervation of coronary arteries and heart
(rats)
ROlHL-17487-04 Adrenergic-vasoregulation interactions in
hypertension (human)
" ROlHL-17706-04 Psychosocial hypertension,
catecholamines and drugs (mice)
** ROlHL-17947-04 Experimental renal and neurogenic
hypertension (human, animals)
(contd)
M Grant has subprojects descnbtng specific research aspects.
See Appendix for investigator's name and grant number.
CAR
102
CAR
ROlHL'17958-04 Circulatory effects of operant
cardiovascular control (baboons)
ROlHL-18579-03 Vasoactive hormones and blood pressure
regulation (dogs, rats, rabbits)
POlHL-1897403 Experimental neurogenic hypertension
program
POlHL-18974-03 0001 Experimental neurogenic
hypertension program - Central neural systems regulating
arterial pressure (rabbits)
POlHL-18974-03 0006 Experimental neurogenic
hypertension program - Model of sustained arterial
hypertension (cats)
POlHL-18974-03 0008
hypertension program
(rats)
POlHL-18974-03 0012
hypertension program
Experimental neurogenic
Monoamines and hypertension
Experimental neurogenic
Immunohistochemistry of central
monoamine neurons (rats)
P01HL18974-03 0014 Experimental neurogenic
hypertension program
POlHL-18974-03 0015
hypertension program
POlHL-18974-03 0016
hypertension program
POlHL-18974-03 0017
hypertension program
Administrative core
Experimental neurogenic
Neurochemistry core
Experimental neurogenic
Neuroanatomy core
Experimental neurogenic
Computer-physiology core
ROlHL-18976-03 Blood pressure control-Relation to
behavioral stress (human, dog)
ROIHL'19048'03 Structure of baroreceptors in
hypertension (rats)
** R01H1.-19144-03 Contraceptive steroids and experimental
hypertension (rats)
** ROlHL-19251-03 An index of sympathetic activity in
hypertension (rats)
ROlHL-19320-03 Angiotensin neuropharmacology-
Relationship to sodium
ROlHL-20542-03 Regional hemodynamics in spontaneous
hypertension (rats)
** POlHL-20581-01 0005 Vascular neuroeffector
mechanisms in health and disease - Changes in the
neuroeffector mechanism in hypertension (rabbits)
** ROlHL-2 1099-02 Subcellular changes of blood vessels in
hypertension (rats)
** R01HL22306-01 Renal catecholamines- Pathophysiology
of hypertension (dogs)
ROlHL-22617-01 Angiotensin, hypertension and the CNS
(sheep)
** R23HL-22747-01 Cardiodynamics and hypertension under
cerebellar control (dogs)
** ROlHL-23201-01 Mechanisms of hypertension (human,
rats)
** ROlHL-23600-01 Ions, water, and hypertension (human,
dogs, rats)
CARDIOVASCULAR DISORDERS, HYPERTENSION
(SYSTEMIC), PROSTAGLANDINS-ASSOCIATED
SEE ALSO FATTY ACIDS, UNSATURATED FATTY ACIDS,
PROSTAGLANDINS
ROlHL-13595-08 Renin and vascular hyper-reactivity In
hypertension (human, rats)
P50HL14192-08 0003 Specialized center of research in
hypertension - Prostaglandins as mediators of renin
secretion (human, dog)
** R01HL14397-07 Hypertension -Angiotensin and
prostaglandin pharmacology (animals)
ROlHL-15447-06 Vascular role of prostaglandin and cyclic
nucleotides (rats)
ROlHL-17487-04 Adrenergic-vasoregulation interactions in
hypertension (human)
** ROlHL-18875-03 Angiotension, prostaglandins, pressure
and the kidney (rats)
** ROlHL-19229-02 Prostaglandins and hypertension (human,
rats, dogs, rabbits)
** ROlHL-19644-03 Etiological factors in hypertension
(human, dogs, rats)
** ROlHL-22225-01 Hormonal regulation of blood pressure
and blood flow (human, animals)
** R23HL-22438-01 The etiology of genetic hypertension
(rats)
CARDIOVASCULAR DISORDERS, HYPERVOLEMIA
POlHL-0683517 0043 Cardiovascular disease • Lett
atrial receptor activity by the sympathetic nervous system
(dogs)
POlHL-0683517 0045 Cardiovascular disease - Pressure-
volume-renin relationship in human hypertension
** POlHL-06835-17 0051 Cardiovascular disease -
Cardiopulmonary volume in hypertension (human)
POIHLI 1678-11 0001 Cardiovascular dynamics and their
control - Body fluid volumes in the genesis of hypertension
(rats, dogs)
CARDIOVASCULAR DISORDERS, HYPOTENSION
SEE ALSO NEUROLOGIC MANIFESTATIONS, SYNCOPE
** ROlHL-00487-29 Vasomotor tone and venous return
(human, dogs, monkeys )
ROlHL-02363-20 Kinetics of water and electrolytes in
shock (dogs, rats)
POlHL-06285-18 0180 Cardiovascular-respiratory
physiology and biochemistry - Vagal C-fibers and their
influence on visceral and somatic function (animals)
ROlHL-09315-15 Coronary insufficiency and myocardial
revascularization (human, dogs)
POlHL-11678-11 0043 Cardiovascular dynamics and their
control ■ Basic mechanisms of circulatory shock (dog)
ROlHL-12493-10 Bioengineering analysis of microvascular
function (cats, rabbits)
ROlHL-12990-09 Control of antidiuretic hormone secretion
and metabolism (dogs, rats, rabbits)
ROlHL-13888-15 Regulation of respiration
POlHL-14388-07 0180 Regulation of the circulation in
pathological states - Regulation of cerebral blood flow
(dogs, monkeys)
ROlHL-18947-02 Indirect mean arterial pressure
(mammals)
** P50HL-191 90-02 0008 Pulmonary SCOR-Pathophysiology,
management of IRDS - Hemodynamics and gas exchange-
Determinants of hypotension (human, infant)
ROlHL-21817-01 Catecholamines, blood pressure and
circulation
** ROlHL-22172-01 Hypotension, renal ischemia and effect of
mannitol (dogs, rats)
ROlHL-22201-01 Pharmacology and chemistry of
nudlbranch toxins (guinea pigs, rats, mice)
** R23HL-22972-01 Microcirculatory function In hypotension
(rats, hamsters)
ROlHL-23653-01 Protection of the ischemic myocardium
(dogs)
CARDIOVASCULAR DISORDERS, HYPOTENSION
POSTURAL
SEE ALSO CONGENITAL ABNORMALITIES, NEUROLOGICAL,
DYSAUTONOMIA FAMILIAL
POlHL-14388-07 0179 Regulation of the circulation in
pathological states - Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
** POlHL-14388-07 0184 Regulation of the circulation in
pathological states - Vestibular reflexes in control of
circulation (human)
POlHL-14388-07 0185
pathological states
rabbits, dogs)
POlHL-14388-07 0208
pathological states
and hypertensive man
POlHL-14388-07 0229
pathological states
(human)
POlHL-14388-07 0232
pathological states
P50HL- 183 18-03 0011
Regulation of the circulation in
Reflex control of venous tone (human,
Regulation of the circulation in
Baroreceptor reflex function in normal
Regulation of the circulation in
Mechanism of postural hypotension
Regulation of the circulation in
Idiopathic cyclic edema
Pathogenesis and complications of
hypertension - Adrenergic function-Renin and
mineralocorticoid activity (human)
P50HL-183 18-03 0019 Pathogenesis and complications of
hypertension - Renin-angiotensin system in blood pressure
regulation (human, rat, dog)
ROlHL-201 24-02 Coronary risk factors (human)
ROlHL-20439-02 Effects of insulin on neurovascular
transmission (human, rats, rabbits, hamsters)
ROlHL-21532-02 Cardiovascular homeostasis and learning
(frogs, rats, human)
R01HL-22051-01 Role of angiotensin II in vasopressin
release (human)
ROlHL-22581-02 Neurocirculatory control in diabetes
mellitus (human)
CARDIOVASCULAR DISORDERS, HYPOVOLEMIA
SEE ALSO CARDIOVASCULAR DISORDERS, HEMORRAGIC
SHOCK
SEE ALSO CARDIOVASCULAR DISORDERS, ISCHEMIA
POlHL-07896-15 0014 Environmental biomedical research
program - Mechanisms of respiration and circulation
(human, dogs)
ROlHL-12493-10 Bioengineering analysis of microvascular
function (cats, rabbits)
POlHL-12738-10 0129 Physiologic pharmacology and its
clinical applications - Receptor specificities and
metabolism of vasopressin analogs
ROlHL-1334106 Lymph -An Indication of splanchnic tissue
respiration (dogs, human, rats)
ROlHL-17091-05 Anesthetics and microvascular response
to hemorrhage (rats)
ROlHL-1899504 Cardiovascular determinants of
catecholamine release (dogs)
P50HL-19185-02 0006 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Evaluation of risk factors
in neonatal respiratory distress (human, sheep)
R01HL19298-03 Pulmonary hemodynamics (dogs, cats)
ROlHL-22406-01 Isobaric vascular bubbles and
decompression sickness (goats, models)
CARDIOVASCULAR DISORDERS, INFARCTION
SEE ALSO CARDIOVASCULAR DISORDERS, ARTERIAL
OCCLUSIONS
SEE ALSO CARDIOVASCULAR DISORDERS, VENOUS
OCCLUSIONS
ROlHL-15231-05 Mechanisms of hemodynamic changes
during digestion (dogs)
ROlHL-18080-03 Extrinsic control of intestinal
microcirculation (dogs)
ROlHL-20 179-02 Epidemiology of sudden cardiac death
among women
ROlHL-22329-01 Active prosthetic myocardium-Effects on
LV function (dogs)
CARDIOVASCULAR DISORDERS, ISCHEMIA
SEE ALSO BLOOD PROTEINS DISORDERS, HYPERVISCOSITY
SYNDROME
SEE ALSO CARDIOVASCULAR DISORDERS, ARTERIAL
OCCLUSIONS
SEE ALSO CARDIOVASCUUR DISORDERS, HYPOVOLEMIA
SEE ALSO CARDIOVASCULAR FUNCTION, BLOOD FLOW,
REACTIVE HYPEREMIA
SEE ALSO CEREBROVASCULAR DISORDERS, BRAIN ISCHEMIA
AND HYPOXIA
SEE ALSO GASTROINTESTINAL CIRCUUTORY DISORDERS,
CIRCULATORY INSUFFICIENCY
SEE ALSO HEART DISORDERS, CORONARY, MYOCARDIAL
ISCHEMIA AND HYPOXIA
SEE ALSO KIDNEY-CIRCULATORY DISORDERS, RENAL
ISCHEMIA AND HYPOXIA
SEE ALSO RESPIRATORY CIRCULATORY DISORDERS,
PULMONARY ISCHEMIA AND HYPOXIA
SEE ALSO SKELETAL DISORDERS, BONE NECROSIS ISCHEMIC
POlHL-08682-15 0019 Regulation of the cardiovascular
system - Hepatic immunophysiology and host-defense in
shock (rat, dog, human)
POlHL-08682-15 0020 Regulation of the cardiovascular
system - Hepatic metabolic basis of shock (rat)
POlHL-13262-07 0011 Arterial wall in atherosclerosis -
Role of hypertension In atherosclerosis (human, monkey,
dog)
ROlHL-14148-07 0009 The regional circulations -
Myocardial circulation in hypertension and atherosclerosis
(human)
P60HL-15168-07 0005 Comprehensive sickle cell disease
center - Ophthalmology (human, rabbits, monkeys)
ROlHL-16236-04 Detailed characteristics of coronary blood
flow (horses, dogs, calves)
P01HL17421-05 0002 Regulation and exchange in the
microcirculation - Metabolic and myogenic blood flow
regulation in microcirculation (animals)
ROlHL-17739-04 Acute myocardial infarct scintigraphy
(human, dogs, rats)
ROlHL-17944-03 Studies in lung preservation (dogs)
ROlHL-18097-04 Pathogenesis of acute renal failure (rats)
R01HL18328-03 Hemoglobin function and tissue
oxygenation (human, dogs)
ROlHL-18984-01 P50 effect on exercise limit in stable
angina (human)
ROlHL-19406-03 Grading of atherosclerosis by CW doppler
ultrasound (human, dogs)
ROlHL-19782-02 Pharmacologic studies on the ischemic
heart (dogs)
ROlHL-20869-01 Microvascular responses to ultrasound
** R23HL-21151-02 Ischemic myocardium-Delivery of blood
flow and drugs (dogs)
ROlHL-2 11 72-02 Regional oxygen consumption of heart
and other organs (animals)
ROlHL-21179-01 Volume regulation-Role of the membrane
potential (amphiuma)
** ROlHL-21843-01 Ischemia, diabetes and the
microcirculation (rats, cats, hamsters)
ROlHL-22231-02 Modulation of calcium control of cardiac
myofibrils (rats)
ROlHL-22741-01 Arteriovenous connections in extremity
revascularization (dogs)
** ROlHL-23 128-01 Cardiac contractility-Ischemia and
hypoxia (rabbits, rats)
CARDIOVASCULAR DISORDERS, PERIPHERAL
VASCULAR DISORDERS
SEE ALSO CARDIOVASCULAR DISORDERS, RAYNAUD'S
DISEASE AND PHENOMENON
SEE ALSO CARDIOVASCULAR DISORDERS, THROMBOPHLEBmS
SEE ALSO CARDIOVASCULAR DISORDERS, VARICOSE ULCER
P01HL-06314-17 0065 Immunologic mechanisms in
cardiovascular disease - Transplantation biology and
clinical transplantation
M POlHL-07293-17 Non-invasive cardiovascular
measurements
POlHL-07293-17 0044 Non-invasive cardiovascular
measurements - Cardiac duplex scanner
** POlHL-07293-17 0055 Non-invasive cardiovascular
measurements - Peripheral vascular transducer position
locating system
ROlHL-13654-08 Antilipemic regimes in peripheral
arteriosclerosis (human)
P50HL-14230-07 0097 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Studies of circulating platelet aggregates
(human)
ROlHL-15512-06 Drug treatment of stenosing primate
atherosclerosis (rabbits, monkeys)
ROlHL-17341-03 Practical total synthesis of
prostaglandins
ROlHL-17407-05 Peripheral circulation and fluid balance
(fish, mammals, human)
ROlHL-17628-03 Pulsatile pressure-flow dynamics (dogs)
ROlHL-17970-04 Vascular effects of inhibitory behavioral
adaptations (dogs)
P50HL-18323-04 0042 SCOR hypertension center - Blood
viscosity and blood volume in hypertensive disease
(human, dog)
** ROlHL-18977-03 Noninvasive diagnosis ot peripheral
arterial disease (human, dogs)
(contd)
'Excludes TOitine methodokigy OR covers only general projects which preclude indexing at the specific level
**Onented stBniftcantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
CAI
PSOHl 19190 0? 0008 PulmonarY SCOR Pithophysioloiy.
m<n<|em«nt ol IRDS Htmodynimici «nd |ij tachantt
0«tttminanti of hypolanslon (human, intanti
ROIHL l92bS 03 Evaluation of diagnostic clln(cal
hamo(rliaolO|y (liuman)
ROIHL 19275 03 Cfiaractaiitallon of collataial blood
vassals (do|s)
ROIHl 19287 03 Tha antihypartansiva function of ttia
renal medulla (human, rats, rabbits)
ROIHL 20177 02 Eflacts ot erythtocyta dalormablllty on
tissue perfusion (rats)
ROIHl 2040003 Diabetic neuropathy and peripheral
vascular diseases (human, hamsters)
ROIHL 20S22 03 Peripheral arterial disease in the diabetic
(human)
ROIHL 20S64'02 Pathogenesis of peripheral arterial
disease (rats, rabbits)
ROIHL 20898 02 Ultrasonic evaluation in direct arterial
surgery (models, cattle, human)
Compensatory responses to arterial
Mechanical interactions between ventricle
Natural history of the postphlebitic
•• R01HL2103401
occlusion (dogs)
R23HL2M6202
arteries (dogs)
" R01HL2157201
syndrome
ROIHL 2247401 Cholesterol metabolism and
atherosclerosis (rats, human, rabbits)
ROIHL 22567-01 Validation of a cholesterol absorption
method in man
** ROIHL 22741-01 Arteriovenous connections in extremity
revascularization (dogs)
ROlHL-2285201 Diagnostic techniques in venous
thromboembolism (human)
ROIHL 22893 01 Evaluating arterial disease by velocity
wave analysis (dogs, human)
CARDIOVASCULAR DISORDERS, RAYNAUD'S
DISEASE AND PHENOMENON
ROIHL 10009-13 Regional lung function in man
** ROlHL-1846703 Fingertip blood flow in normals and
Raynaud's disease (human)
** ROlHL-21323-02 Raynaud's disease and temperature self-
regulation (human)
** ROlHL-2254701 Behavioral treatment of Raynaud's
disease (human)
CARDIOVASCULAR DISORDERS,
THROMBOPHLEBITIS
** ROlHL-17974-03 External pneumatic compression in deep
venous thrombosis (human)
** PO1HL-I8576-03 0013 Thrombosis research program
project - Early warning and monitoring test systems in
thrombotic disease (human)
ROlHL-18738-02 Prevention of postoperative venous
thrombi (human, cattle)
R01HL19839-09 Factors in youth predisposing to chronic
diseases (former college students)
** R01HL-21572-01 Natural history of the postphlebitic
syndrome
CARDIOVASCULAR DISORDERS, THROMBOSIS
SEE ALSO BLOOD COAGULATION DISORDERS. INTRAVASCULAR
COAGUUTION DISSEfVIINATED
SEE ALSO BLOOD COAGULATION TESTS. THROMBIC INDEX*
SEE ALSO CARDIOVASCUUR DISORDERS. ElVIBOLISIi/l.
THROMBOEMBOLISIi/l
SEE ALSO CEREBROVASCUUR DISORDERS. CEREBRAL
OCCLUSIONS AND THROMBOSIS
SEE ALSO HEART DISORDERS. CORONARY OCCLUSIONS AND
THROMBOSIS
NOlHI-32926-10 Analysis of lipoproteins (animals)
ROlHL-01661-27 Hemostatic mechanisms (human)
ROlHL-01803-23 0011 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Immunopathologic consequences of
cigarette smoking (human, rabbits, plants)
** ROlHL-02254-23 Blood coagulation and hemorrhagic
disease (human, animals)
** P01HL-06835-17 0027 Cardiovascular disease - Studies
in thrombosis-cross-linking of fibrinogen (human)
** POlHL-06835-17 0028 Cardiovascular disease - Studies
in thrombosisfibrinogen in fibrin transport (human)
ROlHL-0737913 Structure and function of fibrinogen
(human)
** ROlHL-0990213 Comparative study of coagulation and
vascular disease (animals)
** R01HL10582-12 Thrombosis and hemostasis-Analysis,
methods and standards (human, cattle, venom)
M POIHL-11414-11 Thrombosis and atherosclerosis program
** POlHL-11414-11 0004 Thrombosis and atherosclerosis
program - Platelet function and nonthrombogenic surfaces
(human)
** POlHL-11414-11 0034 Thrombosis and atherosclerosis
program - Servo simulation-Experimental myocardial
infarction (dogs)
** POlHL-11414-11 0037 Thrombosis and atherosclerosis
program - Vascular intimal injury and healing (rabbits.
rats)
** ROlHL-11775-11 Platelet mechanisms in disease (human,
primates)
ROlHL-1 1880-10 Physiology and pathology of blood
platelets (human, dogs)
ROlHL-1 1945-10 Synthesis of artificial lung and kidney
systems (sheep, mice, swine)
103
POIHl 13108 09 0003 Clinical heart traniplintilion
Indomyocardial blop^y palhology
ROIHL 13198 21 Hlood coagulation Physico chemlcil
properties (human, cattle)
P50H1 1414/08 Specialized center of research in
thrombosis
P50HI 14147 08 0001 Specialized center ol research in
thrombosis Role of aspirin, other anti platelet agents in
platelet function (rat. human)
P50HI 14147 08 0003 Specialized center of research in
thrombosis Surface thrombogenicity and phospholipid
vesicle physical properties
P50HL 14147 08 0006 Specialized center of research in
thrombosis Clearance mechanisms of coagulation
moieties (human, rabbits, rodents)
P50HL 14147 08 0007 Specialized center of research in
thrombosis Radioactive tracers in recognition o(
intravascular coagulation (human, dogs)
P50HL 14147 08 0012 Specialized center of research in
thrombosis Tissue culture study of arterial cells (human.
hamster)
PSOHL 14147 08 0013 Specialized center of research in
thrombosis Mathematical models of blood coagulation
kinetics
P50HL 14147 08 0015 Specialized center of research in
thrombosis Charge related properties of phospholipid
surfaces in monolayers and vesicles
' P50HL-14147-08 0016 Specialized center of research In
thrombosrs Nuclear medicine core laboratory (human,
dogs, rats, rabbits)
' P50HL 1414708 0017 Specialized center of research in
thrombosis Core coagulation laboratory (human)
' P50HL-14147 08 0018 Specialized center of research in
thrombosis Biochemical aspects of platelet function in
thrombosis and cell growth (human)
P50HL-142 17-08 Specialized center of research in
thrombosis
* P50HL 14217-08 0048 Specialized center of research in
thrombosis Fibrinolysis section -Structural studies (human,
animal)
' P50HL-1421708 0049 Specialized center of research in
thrombosis - Fibrinolysis section-Clinical studies
* P50HL- 142 17-08 0050 Specialized center of research in
thrombosis - Electron microscopy section (dogs)
■ P50HL-14217 08 0051 Specialized center of research in
thrombosis - Microcirculation section (bat, hamster)
* P50HL- 142 1708 0052 Specialized center of research in
thrombosis - Radioisotope nuclear medicine section
(human, dog)
* P50HL-14217-08 0054 Specialized center of research in
thrombosis - Coagulation section -Platelet aggregation
(human, pig. rabbit, dog)
* P50HL-142 17-08 0055 Specialized center of research in
thrombosis - Coagulation section -Platelet coagulant activity
(human)
P50HL1421708 0057 Specialized center of research in
thrombosis - Pharmacology-Platelet biochemistry (human,
animal)
* P50HL-142 17-08 0063 Specialized center of research in
thrombosis - Special clinical studies laboratory
I P50HL-14230-07 A/S SCOR-Lipids, atherosclerosis and
thrombosis
P50HL-14230-07 0094 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Studies of atherosclerosis and regression
(monkeys)
P50HL14230-07 0095 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Blood platelet adherence to endothelial
smooth muscle cells, fibroblast (human)
P50HL-14230-07 0096 A/S SCOR-Lipids, atherosclerosis
and thrombosis Ultrastructural studies of endothelial cells
(human)
* P50HL- 142 30-07 0097 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Studies of circulating platelet aggregates
(human)
P50HL14236-05 0003 Prevention of premature
arteriosclerosis ■ Intravascular clotting in patients with
hyperlipidemia
ROlHL-14344-07 Platelet function and adenine nucleotide
metabolism (human)
ROlHL-14378-07 Lipemias and reconstructive cardiac
surgery (human)
* ROlHL-14697-07 Role of platelet membranes in
hemostasis (human)
* ROlHL-14739-06 The role of leukocytes in thrombotic
disease (human, dogs)
ROlHL-14890-07 Platelet prostaglandins (human, rabbits)
R01HL14992-07 Mechanism of thrombin action (human)
P60HL15160-07 0015 Center for sickle cell disease •
Lung function abnormalities in sickle cell
hemoglobinopathies (human)
'* ROlHL-15226-06 Interaction of blood cells with fibrinogen
and fibrin (human, animals)
ROlHL-15474-06 Structure and function of the
antihemophilic factor (human, cattle)
I POIHL- 154 86-06 Studies on thrombosis
'* POlHL-1548606 0001 Studies on thrombosis - Studies on
chemistry of fibrinogen (human, dogs)
"* POlHL-15486-06 0002 Studies on thrombosis -
Characterization of antisera to fibrinopeptide B (human,
rabbits)
CAR
POIHl l54K(>0b0003 Studiet on thromboiit
Mechinism and prtvtnlion ol fibtinoptplid* B dtgradatwn
(human)
POIHt 15486 06 0004 Studies on Ihrombotli
Thrombosis, intravascuali coagulilion platalat aggrtfilion
(dogs)
POIHl 15486 06 0005 '.tudies on thrombotit lioltlion
and characterization of PF4 antigens (rabbits)
POl HI 15486 06 0006 Studres on thromboiit Clinical
investigation unit
POIHl 15596 05 Coagulation, fibrinolysis, hemoitiilt and
hepatitis
POIHL 1559605 0001 Coagulation, fibrrnolytit,
hemoslasis and hepatitis Defibrination (human)
POIHl 15596 05 0002 Coagulation, fibrinolysis.
hemostasis and hepatitis Radioimmunoassay of
fibrinogen and fibrin derivatives (human)
POIHL 15596 05 0018 Coagulation, fibrinolysis.
hemostasis and hepatitis Increased plasma lipids on
blood coagulation and thrombosis (human, animals)
ROIHL 1561506 Structure function studies of human
factor Vtll/vWF
ROIHL 15616 04 Platelet membrane proteins in
aggregation (human)
ROIHL 1615405 Membrane lung perfusion for acute
respiratory failure (sheep, baboons)
POIHl 16387 04 0006 The blood vessel and
thrombogenesis Mechanism of delayed vessel graft failure
(dogs, rabbits)
POIHL 16411 04 0003 Blood systems in coagulation and
vessel disease Molecular events involving the late stages
of coagulation (rabbits)
ROIHL 16633-04 Chemistry and biology of factor IX
activator (human, mice, rats)
POlHl-17430-05 0005 Control of coagulation The
activation of prothrombin (human, cattle, dogs)
POlHl-1743005 0006 Control of coagulation ■ Activation
fragments of prothrombin in vitro and in vivo (human.
dogs, cattle)
' R01H117513-04 Role of PF-4 in detecting and promoting
thrombosis (human, primates)
R01HL17729-04 Stimulus-response coupling in platelets
(human)
POlHl-17812-04 Thrombosis and plasma proteins
' POlHL-17812-04 0001 Thrombosis and plasma proteins •
Thrombosis and plasma proteins (cattle, guinea pigs)
' POlHL-17812-04 0002 Thrombosis and plasma proteins -
Activators of fibrinolysis-Synthesis and degradation
(human, cattle)
' POlHL-17812-04 0004 Thrombosis and plasma proteins •
Serum-platelet interaction (human)
* POlHL-17812-04 0005 Thrombosis and plasma proteins ■
In vitro systems of normal platelets, white cells, sera
(human)
* POlHL-17812-04 0007 Thrombosis and plasma proteins ■
Blood components-Response to endotoxin (dogs, baboons)
ROlHL-17964-04 The alternate pathway for fibrinolysis
(human)
R01HL1801204 Cellular defects in nocturnal
hemoglobinuria (human)
ROIHL- 18030-04 The role of contractile proteins in
platelets (human, rabbits)
* ROlHL-18321-03 Fluid shear or magnetic alignment of
blood components (human)
ROlHl-18473-04 Genesis of atherosclerotic lesions
(human, mules)
I POlHL-18576-03 Thrombosis research program project
* POlHL-18576-03 0001 Thrombosis research program
project - Platelet damage from physical forces and
artificial surfaces (human)
* POlHL-1857603 0002 Thrombosis research program
project - Molecular basis of fibrin formation (human, cattle,
lamprey)
* POlHL-18576-03 0003 Thrombosis research program
project ■ Biocompatible materials
* POlHl-1857603 0004 Thrombosis research program
project ' Mechanism and control of collagen-platelet
interaction
* POlHL-18576-03 0005 Thrombosis research program
project - Molecular basis of von Willebrand's disease and
hemophilia (human, cattle)
* POlHL-1857603 0007 Thrombosis research program
project - Relationships between coagulability and
thrombosis (human, animals)
* POlHL-18576-03 0009 Thrombosis research program
project - Biology of factor VII (human, rabbits, cattle)
* POlHL-18576-03 0010 Thrombosis research program
project - Evaluation of nonthrombogenic materials (cattle)
■* POlHL-1857603 0011 Thrombosis research program
project - Proteolysis and platelet function (human, cattle,
rabbits)
'* POlHL-1857603 0012 Thrombosis research program
project - Synthetic anticoagulant and thrombolytic agents
(dogs)
'* POlHL-18576-03 0013 Thrombosis research program
project - Early warning and monitoring test systems in
thrombotic disease (human)
'* POlHl-18576-03 0014 Thrombosis research program
project - Immunology core
'* P01H11857603 0015 Thrombosis research program
project ■ Major equipment core
(contd)
titMiiK routine methodotogy OR cavers only general projects which preclude indexing at the specific level.
**0nented significanthr to above subject.
M Grant has subprojects descnbing specific research aspects.
See Appendix for Investigator's name and grant number
CAR
104
CAR
Platelet collagen interaction (human)
Surgical vascular disorders (human,
Platelet vessel wall Interactions in
POlHL-18576-03 0016 Thrombosis research program
project Radiochemistry core
R01HL18584-03 Effects of physical forces on platelets
(human)
R01HL-1858e-03 Role of platelet lipids in hemostasis and
thrombosis (human)
POlHL-18645-03 0006 Biology of the artery wall and
atherosclerosis • The platelet and atherosclerosis (monkeys,
baboons)
ROlHL-18650-03
ROlHL-18815-03
dogs)
P01HL18827-02
thrombogenesis
P01HL1882702 0001 Platelet vessel wall interactions in
thrombogenesis - Role of endothelial cells in the production
of thrombi (human, cattle)
POlHL-18827 02 0002 Platelet vessel wall interactions in
thrombogenesis • Interactions of vessel wall
raacromolecules with factor XII (human, rats)
P01HL18827-02 0003 Platelet vessel wall interactions in
thrombogenesis • Tumor cell and platelets in
thrombogenesis and metastasis (human, animals)
P01HL18827-02 0005 Platelet vessel wall interactions in
thrombogenesis - Platelet vessel wall interactions in
thrombogenesis (human)
P50HL-18828-03 Specialized center of research in
thrombosis
P50HL-18828-03 0001 Specialized center of research in
thrombosis - Membrane biology and hemostasis (human)
P50HL-18828-03 0003 Specialized center of research in
thrombosis - Structure and function of plasma coagulation
inhibitors (human)
P50HL-18828-03 0005 Specialized center of research in
thrombosis - Platelet inflammatory factors in thrombosis
(human, guinea pig)
P50HL 18828-03 0008 Specialized center of research in
thrombosis - Biochemistry, physiology -Platelets and
subcellular platelet particles (human)
ROlHL-19105-02 Detection and adherence of fibrin
monomer complexes (human)
ROlHL-19131-04 Hypercoagulability and assays for its
protection (human)
ROlHL-19173-03 Analysis of blood trauma from
microporous oxygenators (human, dogs, rabbits)
ROlHL-19225-02 0004 Types and mechanims of
pulmonary hypertension ■ Structural changes in human
pulmonary circulation (human, animals)
ROlHL-19267-02 Serial comparative study of Von
Willebrand's disease (human)
R01H1.-19350-02 Prevention of thrombosis by applied
electric fields (sheep)
ROlHL-19996-02 Role of membrane proteins in platelet
(unction (human, rabbits)
R01HL-20079-02 0001 Thromboresistant material - Active
and passive thromboresistant surfaces
ROlHL-20079-02 0002 Thromboresistant material -
Thromboresistant materials (sheep)
ROlHL-20079-02 0003 Thromboresistant material Blood
surface interactions (human, cattle)
ROlHL-20313-02 Surface-induced thrombosis-Modification
of albumin variants (human, goat)
ROlHL-20337-02 Thromboembolic diseases (human)
ROlHL-20563-02 Restoring microcirculation after platelet
aggregation
ROlHL-20956-02
human platelets
ROlHL-21001-01
vascular grafts
P50HL-21006-02 0006 Specialized center of research in
arteriosclerosis - Intravascular coagulation and thrombosis
in hyperlipidemia (human)
Early events following stimulation of
Protein and thrombus deposition on
Ion and S-hydroxytryptamine transport by
Fibrinogen labeling with radiometals
Structure of factor Vlll-Von Willebrand
ROlHL-21217-01
platelets
ROlHL-21273-02
ROlHL-21379-01
protein (human)
ROlHL-21403-02 Blood clotting kinetics studied by
radioimmunoassay (human)
ROlHL-21460-02 Lipoproteins, hemostasis and
atherosclerosis (human, rabbits)
R23HL-21490-02 Studies of enzymes in human platelet
membranes
ROIHL 221 10-02 Healing complications in vascular
grafting (dogs)
ROlHL-221 19-01 Biochemistry of platelet function in
thrombosis and cell growth (rabbits)
P01HL-22I63-01 Surface thrombogenesis-Mechanisms and
prevention
POlHL-22163-01 0001 Surface thrombogenesis-
Mechanisms and prevention - Initial blood protein and
platelet interactions with biomaterials (baboons)
POlHL-22163-01 0002 Surface thrombogenesis-
Mechanisms and prevention Laser-scattering detection of
microemboli in blood flow (baboons)
POlHL-22163-01 0003 Surface thrombogenesis-
Mechanisms and prevention - In vivo mechanisms of
biomaterial thrombogenesis and its prevention (baboons)
POIHL-2216301 9001 Surface thrombogenesis-
Mechanisms and prevention • Polymers for studing blood
material interactions core
ROlHL-222 19-01 Prostacyclin and peroxides in blood and
membrane disease
** ROlHL-22445-01 Platelet inhibitors-Effect on coronary
bypass grafts (dogs)
ROlHL-2245501 Platelet concentration in the marginal
layer (dogs, human)
ROlHL-22502-01 Role of phosphoinositides in human
platelet secretion
** ROlHL-22527-01 Prostacyclin-thromboxanes in the
cardiovascular system (human, rabbits)
** ROlHL-22583-02 Ultrastructural study of endothelium in
thrombosis (human)
M POlHL-22602-01 Pathophysiology of the endothelium
** POlHL-22602-01 0001 Pathophysiology of the
endothelium - Platelet-endothelial interactions in vitro
(human, cattle)
ROlHL-2262701 An inhibitor of platelet adhesion to
artificial organs (human)
M POlHL-22633-01 Cellular and molecular biology of
lipoprotein metabolism
** POlHL-22633-01 0003 Cellular and molecular biology of
lipoprotein metabolism - Sterol metabolism in platelets and
megakaryocytes (human, rabbits, guinea pigs)
** ROlHL-2273801 Role of bioelectric potentials in platelet
adherence (bats, rats, hamsters)
ROIHL'227 39-01 Evolution and progression of pediatric
atherosclerosis
ROll^L-22888-01 Prosthetic valve endocarditis-Etiology
and therapy (dogs)
NOlHV-52907-04 Interactions of platelets with collagens
(human, mammals)
NOlHV-629 11-04 Vena cava ring tests of biomaterials in
dogs
CARDIOVASCULAR DISORDERS, THROMBOSIS,
VENOUS
SEE ALSO CARDIOVASCULAR DISORDERS, THROMBOPHLEBITIS
POlHL-11414-11 0004 Thrombosis and atherosclerosis
program - Platelet function and nonthrombogenic surfaces
(human)
POlHL'11414-11 0037 Thrombosis and atherosclerosis
program - Vascular intimal injury and healing (rabbits,
rats)
P50HL-14147-08 0007 Specialized center of research in
thrombosis - Radioactive tracers in recognition of
intravascular coagulation (human, dogs)
P50HL-1414708 0016 Specialized center of research in
thrombosis • Nuclear medicine core laboratory (human,
dogs, rats, rabbits)
P50HL14187-07 0008 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses - Pulmonary
thromboembolism (dogs, human)
P50HL-142 17-08 0048 Specialized center of research in
thrombosis - Fibrinolysis section -Structural studies (human,
animal)
P50HL-1421708 0049 Specialized center of research in
thrombosis - Fibrinolysis section-Clinical studies
P50HL142 17-08 0050 Specialized center of research In
thrombosis - Electron microscopy section (dogs)
P50HL-142 17-08 0052 Specialized center of research in
thrombosis - Radioisotope nuclear medicine section
(human, dog)
P50HL142 17-08 0055 Specialized center of research in
thrombosis - Coagulation section-Platelet coagulant activity
(human)
ROlHL-20337-02 Thromboembolic diseases (human)
** ROlHL-21572-01 Natural history of the postphlebitic
syndrome
ROlHL-22852-01 Diagnostic techniques in venous
thromboembolism (human)
ROlHL-22946-01 Prostaglandins, platelet aggregation and
vasoactivity (human, rats, rabbits)
CARDIOVASCULAR DISORDERS, VARICOSE
ULCER
** P60HL-232 82-01 0003 Comprehensive hospital/community
sickle cell center • Treatment of sickle cell ulcers with
physical therapy and vitamin E (human)
CARDIOVASCULAR DISORDERS, VASCULAR
DISORDERS (GENERAL)
SEE ALSO CEREBROVASCUUR DISORDERS
POlHL-08805-15 0049 Regulation of ventilation and
pulmonary circulation - Pulmonary hypertension produced
by Dirofilaria immitis in the dog
** POlHL-11310-12 0101 Mechanisms of cardiovascular
disease - Molecular pathogenesis of vascular disease
R01HL1188010 Physiology and pathology of blood
platelets (human, dogs)
ROlHL-12085-10 Lipoprotein-carbohydrate metabolism
(human, rats)
** ROlHL-12557-09 Effects of steroids and pregnancy on
arteries and veins (guinea pigs)
** ROlHL-12561-11 Cardiovascular studies on copper
deficiency (swine)
** ROlHL-13694-08 Capillary basement membrane in
cardiovascular disease (human, rats)
R01HL1589505 In vitro study of lipoproteins in vascular
disease (human, animals)
** ROlHL-162 19-05 Mechanisms of atherogenesis in chronic
uremia (human, rats)
ROlHL-16236-04 Detailed characteristics of coronary blood
flow (horses, dogs, calves)
ROlHL-16768-04 The sympathetic nervous system and the
arterial wall (rabbits, pigeons)
Cardiovascular pathology (rats, rabbits)
Endothelial injury and regeneration (rats)
Neural factors in atherogenesis (squirrel
R01HL16952-05
ROlHL-17747-04
ROlHL-18085-03
monkeys)
ROlHL'18152-03 Vascular injury and atherosclerosis
(mice, coxsackievirus)
R01HL18815-03 Surgical vascular disorders (human,
dogs)
ROlHL-19175-03 Pituitary modulation of micro-and macro-
vascular disease (human, rats)
ROlHL-19287-03 The antihypertensive function of the
renal medulla (human, rats, rabbits)
R01HL19677-03 Venous structure and function (dogs)
ROlHL-20054-02 Cultured blood vessel cells-
Pathophysiology (human, animals)
ROlHL-20197'02 Maintenance and repair of vascular
endothelium (human, animals)
ROlHL-20206-02 Carbohydrates-nucleotldes and adrenergic
interactions (rabbits, cats, rats)
ROlHL-20835-02
blood
R23HL-21320-02
Signal analysis of turbulence study in
Cyclic nucleotide metabolism in vascular
endothelium
R23HL-21327-02 Molecular mechanisms of chemical
myocardiopathies (rats)
** R23HL-21950-01 Endothelial cell mechanisms in vascular
disease (human)
R23HL-22075-01 Metabolism of arachidonic acid in blood
vessels (chickens, mammals)
** ROlHL-22121-02 Dyslipoproteinemia in diabetes and
vascular disease (human)
ROlHL-2260401 Non-invasive system for arteriosclerosis
studies (human)
** ROlHL-2278401 Ductus arteriosus closure-An arterial
lesion model (rabbits)
** ROlHL-22939-01 Human kinin and fibrinolytic systems
and renal disease (human)
NOlHV-12157-14 Lipid research clinic (human)
CARDIOVASCULAR DISORDERS,
VASODILATATION
SEE ALSO CARDIOVASCULAR DISORDERS, ANEURYSM
SEE ALSO CARDIOVASCULAR DISORDERS, VARICOSE ULCER
SEE ALSO GASTROINTESTINAL CIRCUUTORY DISORDERS.
ESOPHAGEAL VARICES
SEE ALSO METABOLIC DISORDERS INBORN. ANGIONEUROTIC
EDEMA (HEREDITARY)
POlHL-06314-17 0065 Immunologic mechanisms in
cardiovascular disease - Transplantation biology and
clinical transplantation
POlHL-14388-07 0163 Regulation of the circulation in
pathological states - Adrenergic receptors in coronary
vessels (dogs)
POlHL-14388-07 0180
pathological states -
(dogs, monkeys)
POlHL-14388-07 0231
pathological states
Regulation of the circulation In
Regulation of cerebral blood flow
Regulation of the circulation In
Mechansim of cutaneous
vasodilatation in Paget's disease of bone
ROlHL-15522-06 Influence of mannitol on ischemia
cardiac muscle (dogs. cats, rats)
R01HL16412-04 Release of nucleosides from the ischemic
heart (human, dogs)
POlHL-16910-05 0006 Regulation of the peripheral
circulation - Regulation of blood flow distribution (baboons,
dogs)
P60HL-17269-04 0023 National heart and blood vessel
research and demonstration center - Cardiovascular
pharmacology-Ischemia, shock and heart failure (dog. cat,
rat)
ROlHL-17628-03 Pulsatile pressure-flow dynamics (dogs)
ROIHL 17759-03 Studies of myocardial reactive hyperemia
(dogs, human)
ROIHL- 17903-03 Regional circulatory responses to hypoxia
(rats. cats, rabbits)
ROlHL'17954-03 Narcotics and the circulation (human,
dogs. pigs, monkeys)
ROlHL-18492-03 Measurement of regional coronary flow
reserve (human, dogs)
POlHL-19242-02 0003 Study of vascular smooth muscle -
Vasoactive metabolites from vascular muscle and
parenchymal tissue (animal)
ROlHL-20598-03 The coronary vascular response to
ischemia (dogs, pigs)
ROlHL-20827-02 Effects of hypertrophy on the coronary
circulation (dogs)
R23HL-21434-02 Intrinsic control of coronary blood flow by
chemicals (guinea pigs)
ROlHL-22547-01 Behavioral treatment of Raynaud's
disease (human)
ROlHL-22873-01 Adrenoceptor interconversion and
hormone homeostasis
ROlHL-22952-01 Validation of quantitative coronary
arteriography (dogs)
ROlHL-23211-01 Active normoxic pulmonary vasodilatation
(rat, dog. sheep)
ROlHL-23312-01 Hemodynamics and vasoactivity in renal
hypertension (human, dogs)
ROlHL-23600-01 Ions, water, and hypertension (human.
dogs, rats)
(contd)
^Excludes routine methodokigy OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subiect
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
CAR
CARDIOVASCULAR DISORDERS, VASOSPASM
ROIHL l?/'bOB C«i»b>jl inicioiiiLUldlion (micii)
POIIU I38bl 16 Cyclolioii pioducsd isoloprs in biology
mid medicint (liuiiiaiv aniinaK)
ROIHL 1580b 06 Ceiibrd iiltiial tone ind raictlvity
(labbits)
PbOHL W646 04 COM Study ot ijcbemic haart diseaia
Piogrssjioii ot ijchamic iniuiy m conscious dogs (also
rabbits)
PSOHl 1768^04 0021 Study ol ischemic heart disease
Prostaglandin biosynthesis in blood vessels from ischemic
myocaidium (lat. sheep)
ROIHL 1893? 03 Brain microcirculation observed in vivo
atter trauma (mice)
R13HL2076S01 Eleventh Princeton Conterence on
Cerebrovascular Disease (new lersey)
ROIHL 20787 07 Thromboxanes and prostaglandins
Biochemical pharmacology (rabbits, human)
ROIHL 2118/ 01 Potassium, norepinephiine, and coronary
arterial tone (dogs)
R01HL2I323 02 Raynaud's disease and temperature self
regulation (human)
•• ROIHL 22b7301 Irealment ot post surgical
vasoconstriction (dogs, monkeys, human, rats)
CARDIOVASCULAR DISORDERS, VENOUS
OCCLUSIONS
SEE ALSO CARDIOVASCULAR DISORDERS, EMBOLISM
SEE ALSO CARDIOVASCULAR DISORDERS, INFARCTION
SEE ALSO CARDIOVASCUUR DISORDERS. THROMBOPHLEBITIS
SEE ALSO CARDIOVASCUUR DISORDERS. THROMBOSIS,
VENOUS
SEE ALSO CARDIOVASCUUR SURGERY. VASCUUR
OCCLUSION THERAPEUTIC
R01HL137b4 08 Postoperative thromboembolism in
surgical patients (human)
P01HL16910-05 0001 Regulation ol the peripheral
circulation Quantitative studies of microcirculatory control
(bats)
ROIHL'20835'02 Signal analysis of turbulence study in
blood
CARDIOVASCULAR DISORDERS CHEMOTHERAPY
SEE ALSO CARDIOVASCULAR AGENTS
SEE ALSO CARDIOVASCUUR PHARMACOLOGY
SEE ALSO HEART DISORDERS CHEMOTHERAPY
ROlHL-03181-21 0025 Hemodynamics as applied to
surgical problems - Vascular stenosis (dogs)
ROlHL-03181-21 0027 Hemodynamics as applied to
surgical problems Hemodynamic studies of the Gl tract
(dogs)
POlHL-0466418 0013 Cardiovascular and lung dynamics
• Ventricular function in coronary disease using NTG and
ventriculograms (human)
** ROlHL-05875-18 Pathologic metabolic and physiologic
studies of heart (human, dogs, cats)
P01HL-06285I8 0154 Cardiovascular-respiratory
physiology and biochemistry Function and viability of
critically ischemic myocardium (dogs)
POlHL-06835-17 0045 Cardiovascular disease ■ Pressure-
volume-renin relationship in human hypertension
POlHL-0683517 0046 Cardiovascular disease - Renin
activity during salt depletion in essential hypertension
(human)
POlHL-06835-17 0053 Cardiovascular disease -
Vasodilating drugs (human)
** POlHL-06835-17 0057 Cardiovascular disease - Studies
on cardiac hypertrophy
POlHL-06835-17 0060 Cardiovascular disease
Ventricular performance experimental models of arterial
hypertension (rats, dogs)
** ROlHL-10445-09 Cooperative study of drugs and coronary
heart disease (men)
ROlHL-10503-13 Cardiac ion transport and ultrastructure
(rats, guinea pigs, rabbits)
ROlHL-10582-12 Thrombosis and hemostasis-Analysis.
methods and standards (human, cattle, venom)
ROlHL-10711-12 Cooperative study ot treatment of
hypertension (human)
POlHL-1 1414-11 0014 Thrombosis and atherosclerosis
program - Role of adrenal in human essential hypertension
ROIHL 11775-11 Platelet mechanisms in disease (human,
primates)
POlHL-12738-10 0001 Physiologic pharmacology and its
clinical applications - Clinical pharmacology of cardioactive
drugs (human)
ROlHL-13193-09 Pathophysiology of posttraumatic and
shock states (rodents, dogs)
POlHL-13262-07 0011 Arterial wall in atherosclerosis -
Role of hypertension in atherosclerosis (human, monkey.
dog)
ROlHL-13595-08 Renin and vascular hyperreactivity in
hypertension (human, rats)
ROlHL-13654-08 Antihpcmic regimes in peripheral
arteriosclerosis (human)
ROlHL-13936-06 Microvascular responses in hypertension
(human, rats)
ROlHL-14127-16 Methemoglobinemia and antihypertensive
drugs (cats. mice, rats)
P50HL-14187-07 0005 Pulmonary SCOR -Chemical
mediators in pulmonary vascular responses - Pulmonary
hypertension and cardiac function (dogs, human)
105
P50HL 14187 0/ 0008 Pulmonary SCOR Chemical
mediators in pulmonary vascular rijponiei Pulmoniry
thromboeinbolnni (dogs, human)
P50HI 14192 08 0001 Specialized center ol research In
hypeitiinsion Surgical and medical treatment ol
lonovasculai hypertension (human)
P50HL 14192 08 0002 Specialized center ol research in
hypertension Hypertensive patients with renal artery
stenosis
P50HL 14197 07 0006 Support lor center ol research on
arteriosclerosis Diets and drugs allecting lipid
metabolism (human)
P50HI 14217 08 0049 Specialized center of research in
thrombosis Fibrinolysis section Clinical studies
P50HL 14236 05 Prevention ol premature arteriosclerosis
PbOHL 14236 05 0002 Prevention ol premature
arteriosclerosis Myocardial blood flow in patients with
coronary artherosclerosis
P50HL 1423605 0009 Prevention ol premature
arteriosclerosis ■ Clinical studies on cholesterol metabolism
(human)
Regulation of the circulation in
Myocardial ischemia and infarction in
Regulation of the circulation in
Pharmacology of the coronary
Regulation of the circulation in
Mechanism of postural hypotension
POIHL 1438807 0219
pathological states
animals (dogs)
POIHL 1438807 0220
pathological states
circulation in man
POIHL 1438807 0229
pathological states
(human)
ROIHL 1439707 Hypertension Angiotensin and
prostaglandin pharmacology (animals)
ROIHL 14644 05 Optimization diastolic augmentation and
systolic sink (dogs)
R01HL14944-07 Renal vascular reactivity in hypertensive
patient
P50HL 15062-07 0018 Study of lipoproteins, artery wall,
and atherosclerosis ■ Reversal of atherosclerosis in
monkeys
ROIHL 15374-03 Cooperative study of drugs and coronary
heart disease (human)
ROlHL-15476 05 Mechanism and control of sterol
biosynthesis (rats)
ROlHL-15512 06 Drug treatment of stenosing primate
atherosclerosis (rabbits, monkeys)
ROlHL-15607-06 Physiological control of splanchnic
circulation (dogs)
ROlHL-15681-06 Coronary flow studies of partially
obstructed vessels (dogs)
ROlHL-164 12-04 Release of nucleosides from the ischemic
heart (human, dogs)
ROIHL-16437-05 Drug treatment of atherosclerosis
(rabbits, monkeys)
ROIHL 16587-04 Cholesteiol binding saponins and
atherosclerosis (monkeys)
ROlHL-17335-05 Contractile properties of hypertensive
arterioles (rats)
ROlHL-17341-03 Practical total synthesis of
prostaglandins
P50HL-17648-04 0011 Study ot ischemic heart disease -
Surgical treatment for acute myocardial ischemia (human,
dogs)
P50HL-17651-04 0043 Ischemic heart disease specialized
center of research - Gradual reperfusion following acute
coronary occlusion (dog)
ROlHL-17749-03 Adrenocortical factors in human
hypertension (human)
ROlHL-177 54-03 Pathogenesis and prevention of
hypertension sequelae (rats)
POlHL-17871-04 0009 Kidney, sodium, cardiac output.
arterioles and hypertension - Kidney, sodium, cardiac
output, arterioles and hypertension
ROlHL-18002-03
function (rats)
ROlHL-180 19-04
(mice)
ROlHL-18096-04
(primates, dogs)
ROlHL-18175-03
community
ROlHL-18292-04
delivery (dog. hamster)
P50HL-183 18-03 0001 Pathogenesis and complications of
hypertension - Core clinical program
P50HL- 183 18-03 0011 Pathogenesis and complications of
hypertension - Adrenergic function-Renin and
mineralocorticoid activity (human)
P50HL-183 18-03 0014 Pathogenesis and complications of
hypertension - Arterial metabolism and atherogenesis (rat.
rabbit)
P50HL-18323-04 SCOR hypertension center
P50HL-18323-04 0012 SCOR hypertension center - Renin
as a risk factor (human)
P50HL-183 23-04 0035 SCOR hypertension center - Control
of high blood pressure at the work site
P50HL-18323-04 0043 SCOR hypertension center -
Pharmacology -Renin aldosterone mechanisms in essential
hypertension (human)
P50HL-18323-04 0045 SCOR hypertension center -
Laboratory programs-Prorenin (human)
ROlHL-18333-05 Thrombogenesis and hemostatic balance
(rabbits, human)
Circulatory shock, trauma and RE-system
The endocrine kidney in hypertension
Vasoactive agents in splanchnic viscera
Drug taking for hypertension in a rural
Vasodilation and microvascular oxygen
r AD
R2bHI IR4I4 01 Hypertentiun family •.tialifif. t«i
patient adherence
R7bHl 1841803 Roll ol a lupporting partner in
adherence (human)
R25HI 18424 03 Blood pxiiura education in an induilrial
letting (human)
ROIHI 18467 03 fingertip blood flow in noimalt and
Raynaud'^ disease (human)
POIHl 185/4 03 0006 lipoprotein methodology and
biomedical applications Lipoprotein translormalion.
lipolytic enzymes, diet and lipid lowering agents
ROIHI 1859902 Cardiovascular pharmacology of
lonophores (dogs)
ROIHL 1860/ 03 Metabolic and drug studies on
experimental tat embolism (mice)
ROIHL 18629 04 Influence of aging and hypertension on
the myocardium (rats)
POIHL 18645 03 0006 Biology of the artery wall and
atherosclerosis The platelet and atherosclerosis (monkeys.
baboons)
POIHL 18/08 03 0010 Oxygen, energy and contractility in
cardiac tissue Tissue oxygen utilization (rats, dogs)
ROIHL 18/3802 Prevention of postoperative venous
thrombi (human, cattle)
ROIHL 1925503 Evaluation of diagnostic clinical
hemorrheology (human)
P50HL 19362 02 0010 A/S SCOR Atherosclerosis in
nonhuman primates Antihypertensive therapy
Atherogenesis in experimental hypertension (baboon)
ROIHL 19568-03 Hypertension Analysis of drug and
behavioral therapies (human)
ROIHL 19673 03 Surgical aspects of shock and hypoxia
(dogs, monkeys, rats)
' ROIHL 20000-03 Iron overload in homozygous beta
thalassemia (human)
ROlHL-202 18-02 Fibrinogen catabolism and intravascular
coagulation (human)
ROIHL 2024402
ROlHL-20245-01
ROlHL-20247-01
ROlHL-20248 01
ROIHL 20262-02
he impact of hypertension information
The impact of hypertension information
The impact of hypertension information
The impact of hypertension information
Cardiac glycosides and the mechanism
of the sodium-potassium pump
ROlHL-20337-02 Thromboembolic diseases (human)
ROlHL-20455-03 Role of systemic hypertension on diabetic
retinopathy (human)
ROlHL-20542-03 Regional hemodynamics in spontaneous
hypertension (rats)
POlHL-20552-02 The development and regression of
cardiac hypertrophy
POlHL-20552-02 0002 The development and regression of
cardiac hypertrophy - Effect of treatment on the
hypertrophied left ventricle (rats)
POlHL-20552-02 0003 The development and regression of
cardiac hypertrophy - Muscle mechanics of the
hypertrophied left ventricle (rats)
ROlHL-20572-02 Hemodynamic relations to metabolism in
hypertension
ROlHL-20572-02 0003 Hemodynamic relations to
metabolism in hypertension - Cardiac output and organ
blood flow in hypertension (rats)
ROlHL-20604-03 Sympathectomy -Cardiovascular and
molecular pharmacology (animals)
ROlHL-20678-02 Cardiovascular adaptation to stress in
disease states (dogs)
Population dynamics of arterial
- Modifications of cholesterol balance
divisions (swine)
Population dynamics of arterial
Drugs other than hypolipidemic
drugs affecting atherosclerosis (swine, rabbits)
P50HL-2 1006-02 0001 Specialized center of research in
arteriosclerosis - Clinic and core program
ROlHL-21105-02 Organ specific drugs -Cardiovascular and
renal effects (dogs)
ROlHL-21460-02 Lipoproteins, hemostasis and
atherosclerosis (human, rabbits)
ROlHL-21476-02 Anticoagulant drug absorption
interactions (rats)
ROlHL-21672-01 Antiarrhythmic drug action on VMAZ of
cardiac cells
ROlHL-21996-01 Alteration of digitalis and aldosterone
disposition (rats, rabbits, mice, dogs)
ROlHL-22216-02 Vascular mechanisms in renal
hypertension (dogs)
ROlHL-22219-01 Prostacyclin and peroxides in blood and
membrane disease
ROlHL-22288-01 Renin and precursors -Structure and
function (mice)
ROlHL-22298-02
R23HL-22309-01
immature dogs
R23HL-22345-02 0002 Behavioral cardiovascular
compliance strategies - Compliance with antihypertensive
medication regimens (human)
ROlHL-22445-01 Platelet inhibitors -Effect on coronary
bypass grafts (dogs)
ROlHL-22506-01 Hemodynamics of the clinical
hypertensions
ROlHL-22563-02 Prostaglandins, the kidney and
hypertension (rats)
(contd)
POlHL-20993-02 0004
cells in atherogenesis
related to arterial cell
POlHL-20993-02 0005
cells in atherogenesis
Origins of hypertension (human)
Cardiovascular pharmacodynsi- 1 :
'Excludes routine methodokigy OR covers only general projects which preclude indexing at the specific level.
''Oriented significantly to above subject
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
CAR
106
CAR
ROlHL-22566-01 Mesoionic purinones as
phosphodiesterase inhibitors
ROlHL-22573-01 Treatment of post surgical
vasoconstriction (dogs, monlieys, human, rats)
R23HL-22575-01 Factors modifying cardiac digoxin effects
and content (dogs, cats)
ROlHL-226 12-01 Stabilized prostacyclins to treat vascular
disease
ROlHL-22718-01 Cardiovascular drug interactions-
Metabolism models (dogs)
R23HL'22882'01 Modulation by disease of effect of
furosemide in man
Lipid research clinic
Lipid research clinic (human)
Establishment of a lipid research clinic
Lipid research clinic
Establishment of a lipid research clinic
Therapy for hypertension in the general
Lipid research clinic
Establishment of a lipid research clinic
Therapy for hypertension in general
Therapy for hypertension in general
Therapy for hypertension in general
Hypertension detection and follow-up
NOlHV-12156-10
NOlHV-12157-14
N01HV12158-10
NOlHV-12159-09
NOlHV-12160-15
NOlHV-1243411
population
NOlHV-12435-15 Therapy for hypertension in the general
population (human)
NOIHV 12436-15 Hypertension therapy in the general
population (human)
N01HV12440-14 Therapy for hypertension in the general
population (human)
NOlHV-12442-14 Therapy for hypertension in the general
population (human)
NOlHV-22913-09
NOlHV-22914-08
NOlHV-22931-14
population
NOlHV-22937-07
population
NOlHV-22938-11
population
NOlHV-22939-12
program center
NOlHV-22945-11 Cooperative hypertension detection and
follow-up study (human)
NOlHV-22971-07 Prevention of coronary heart disease
(human)
NOlHV-22976-07 Multiple risk factor intervention trial,
prevention of coronary heart disease
NOlHV-22977-08 Intervention trial for the prevention of
coronary heart disease (human)
NOIHV 22979-07 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22980-06 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-2298110 Intervention trial for the prevention of
coronary heart disease (human)
' NOlHV-2298207 Intervention trial for prevention of
coronary heart disease (human)
NOlHV-22983-07 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-32931-09 Establishment of a lipid research clinic
center
' N01HV-33101-06 Development and conduct of a multiple
risk factor intervention trial (human)
NOlHV-33105-09 Intervention trial for prevention of
coronary heart disease (human)
f<01HV-33 106-06 Intervention trial for the prevention of
coronary heart disease (human)
' NOlHV-33108-04 Prevention of coronary heart disease
(human)
' NOlHV-33109-04 Intervention trial for the prevention of
coronary heart disease (human)
' NOlHV-331 10-04 Prevention of coronary heart disease
(human)
NOlHV-42929-08 Risk factor intervention trial for the
prevention of CHD (human)
NOlHV-42930-09 Risk factor Intervention trial for the
prevention of CHO (human)
NOlHV-42931-07 Risk factor intervention trail for the
prevention of CHD (men)
NOlHV-42932-05 Risk factor intervention trial for the
prevention of CHD (human)
' NOlHV-42933-09 Multiple risk factors in coronary heart
disease (human)
NO lHV-530 15-09
(human)
NOlHV-62900-00
(human)
NOlHV-7291502
population
' NOlHV-7295304
' NOlHV-72961-03
■ NOIHV- 729 79-01
Data Center
' N01HV82915-01
Establishment of a lipid research clinic
Study of breast cancer and reserpine use
Therapy for hypertension in the general
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Therapy to protect ischemic myocardium -
Therapy for hypertension in the general
population (human)
CARDIOVASCULAR DISORDERS DIAGNOSIS*
SEE ALSO CARDIOVASCUUR VISUALIZATION*
SEE ALSO CEREBROVASCULAR DISORDERS DIAGNOSIS (INCL
EXAMS)*
SEE ALSO HEART DISORDERS DIAGNOSIS (INCL EXAMS)*
NOlHI-02216-10 To develop biological flow NMR concept
(human, mammals non human)
*• ROlHL-03181-21 0020 Hemodynamics as applied to
surgical problems - Blood flow measurement- Cardiac
output and regional flows (dogs)
M POlHL-04664-18 Cardiovascular and lung dynamics
POlHL-04664-18 0001 Cardiovascular and lung dynamics
- X-ray projection image videodensitometry (dogs)
POlHL-04664-18 0007 Cardiovascular and lung dynamics
- Development and application of ultrasound imaging
techniques
POlHL-04664-18 0009 Cardiovascular and lung dynamics
- Biological signal and image processing techniques (dogs)
ROlHL-05694-20 Functional pathology of cardiovascular
disease (human)
POlHL-06285-18 0156 Cardiovascular-respiratory
physiology and biochemistry - Myocardial performance
following revascularization (human)
POlHL-06285-18 0157 Cardiovascular-respiratory
physiology and biochemistry - Left ventricle outflow
impedance analysis (human)
POlHL-06835-17 0014 Cardiovascular disease - Dietary
induction of severe atherosclerosis and its prevention
(dogs)
POlHL-06835-17 0015 Cardiovascular disease - Plasma
cholesterol esterification in canine atherosclerosis
POlHL-07293-17 Non-invasive cardiovascular
measurements
POlHL-07293-17 0054 Non-invasive cardiovascular
measurements - Detection of arterial occlusive disease
(human)
POlHL-07293-17 0055 Non-invasive cardiovascular
measurements - Peripheral vascular transducer position
locating system
POlHL'07293-17 0056 Non-invasive cardiovascular
measurements - Peripheral vascular system software
POlHL-0729317 0057 Non-invasive cardiovascular
measurements - Peripheral vascular scanner engineering
evaluation and error analysis (human)
POlHL-07293-17 0058 Non-invasive cardiovascular
measurements - Peripheral duplex scanner physiologic
evaluation
ROlHL-07575-15
data
■ ROlHL-10160-13
R01HL11046-12
Analysis of time-coherent cardiovascular
Origins of atherosclerosis (human)
Renin, angiotensin, steroids, ions and
blood pressure (human, sheep, rabbits)
ROlHL-11717-09 Effect of stenotic obstructions on flow in
arteries (dogs)
ROlHL-127 11-09 Mathematical approach to cardiovascular
mechanics (human, animals)
ROlHL-127 15-10 Dynamic cardiovascular measurement
using ultrasound
POlHL-13262-07 0024 Arterial wall in atherosclerosis -
Serial ocular changes in arteriosclerosis and hypertension
ROlHL'13595-08 Renin and vascular hyper-reactivity in
hypertension (human, rats)
ROlHL-13636-08 Effects of pharmacologic agents on heart
metabolism (human, rodents)
ROIHL- 136 54-08 Antilipemic regimes in peripheral
arteriosclerosis (human)
P50HL14138-05 0008 Center for research on
atherosclerosis - Core lipid laboratory (human)
P50HL-1414708 0007 Specialized center of research in
thrombosis - Radioactive tracers in recognition of
intravascular coagulation (human, dogs)
P50HL141 47-08 0017 Specialized center of research in
thrombosis - Core coagulation laboratory (human)
ROlHL-14148-07 0009 The regional circulations ■
Myocardial circulation in hypertension and atherosclerosis
(human)
P50HL-141 59-08 0024 Specialized center of research in
hypertension - Core resources (clinical, animal models)
P50HL-14 192-08 0005 Specialized center of research in
hypertension ■ New techniques for recognition of
renovascular hypertension (human, dogs)
P50HL- 142 17-08 0049 Specialized center of research in
thrombosis ■ Fibrinolysis section-Clinical studies
P50HL-14217-08 0052 Specialized center of research in
thrombosis - Radioisotope nuclear medicine section
(human, dog)
P50HL-142 17-08 0063 Specialized center of research in
thrombosis - Special clinical studies laboratory
P50HL-14236-05 0003 Prevention of premature
arteriosclerosis - Intravascular clotting in patients with
hyperiipidemia
POlHL-14388-07 0194 Regulation of the circulation in
pathological states - Dopamine-beta-hydroxylase localization
and release in hypertension
POIHL'1438807 0220 Regulation of the circulation in
pathological states - Pharmacology of the coronary
circulation in man
POlHL-14388-07 0221
pathological states
(dogs)
ROlHL-15047-06 Digital computer analysis of the
electrocardiogram (human)
P50HL-15103-07 0001 A/S SCOR -Early natural history of
arteriosclerosis - Clinical research-Bogalusa heart study
(children)
ROlHL-15308-07 Assays for peptides of lipoproteins
(human)
ROlHL-17513-04 Role of PF-4 in detecting and promoting
thrombosis (human, primates)
ROlHL'17578-04 Exercise performance in children with
heart disease
ROlHL-17531-03 Development of electromagnetic
rheoangiography (human, dogs)
Regulation of the circulation in
Experimental myocardial infarction
Wearable blood pressure and ECG
Electro-optical dyes as probes of heart
Peripheral venomotor control in thermal
Preprocessor system for cardiograms
ROIHL- 17604-03
recording system
ROlHL-17702-04
excitability
ROlHL-17732-03
stress (human)
ROlHL-17739-04 Acute myocardial infarct scintigraphy
(human, dogs, rats)
R01HL17826-04 Oxygen delivery to tissue (rat, dog)
ROlHL-18019-04 The endocrine kidney In hypertension
(mice)
ROlHL-18144-03
(human)
P50HL-18318-03 0001 Pathogenesis and complications of
hypertension - Core clinical program
P50HL-183 18-03 0003 Pathogenesis and complications of
hypertension - Core biochemical laboratory
P50HL-18323-04 0011 SCOR hypertension center -
Endocrine profiling on a selected normal population
(human)
P50HL18323-04 0012 SCOR hypertension center - Renin
as a risk factor (human)
P50HL 18323-04 0035 SCOR hypertension center - Control
of high blood pressure at the worii site
P50HL18323-04 0037 SCOR hypertension center -
Adrenocortical factors in childhood hypertension
ROlHL-18456-03 Cardiovascular follow-up of hypertensive
adolescents
POIHL-18576-03 0013 Thrombosis research program
project - Eariy warning and monitoring test systems in
thrombotic disease (human)
ROlHL-18715-02 Hypertension incidence project (human)
R01HL18730-03 Role of mineralocorticoids in low renin
hypertension (human, rats)
ROlHL-18873-02 Early radiologic diagnosis of cardiac
failure (monkey)
ROlHL-18907-03 Objective evaluation early after Ml and
heart surgery (human)
ROlHL-18933-03 Energy output and efficiency of left
ventricle (dog)
ROIHL- 18977-03 Non-invasive diagnosis of peripheral
arterial disease (human, dogs)
ROlHL-19038-02 Plethysmographic evaluation of carotid
blood flow (human, rabbits, dogs)
ROlHL-19175-03 Pituitary modulation of micro-and macro-
vascular disease (human, rats)
' ROlHL-19251-03 An index of sympathetic activity in
hypertension (rats)
' ROlHL-19255-03 Evaluation of diagnostic clinical
hemorrheology (human)
ROlHL-19341-03 Ultrasonic detection of the atherosclerotic
plaque
* P50HL-19362-02 0011 A/S SCOR-Atherosclerosis in
nonhuman primates - Chronic hypertension induced by
operant conditioning techniques (baboon)
ROIHL- 19406-03 Grading of atherosclerosis by CW doppler
ultrasound (human, dogs)
ROlHL-19844-02 Behavioral control of essential
hypertension (human)
ROIHL- 19930-03
newborn twins
ROlHL-20373-02
women
' ROlHL-20630-03 Development of a pulsed Doppler velocity
detector (human, animals)
' ROlHL-20807-02 Detection of familial hypercholesterolemia
(human)
R23HL-21151-02 Ischemic myocardium-Delivery of blood
flow and drugs (dogs)
* ROlHL-2 1548-01 Pathogenesis of pulmonary
thromboembolic disease (human, mammals)
ROlHL-21572-01 Natural history of the postphlebitic
syndrome
* ROlHL-2175611 Vascular disease-Cytochemistry and
ultrastructure (human, rats, mice, hamsters)
R23HL-21917-01 Adrenal steroids in adolescent and adult
hypertension
ROlHL-21971-01 Atherosclerotic disease and risk factors
in twins (human)
ROlHL-22212-01 Alameda county high blood pressure
control program
ROlHL-22255-01 The etiology/prevalence of peripheral
arterial disease (human)
ROlHL-22474-01 Cholesterol metabolism and
atherosclerosis (rats, human, rabbits)
ROlHL-22547-01
disease (human)
* ROlHL-22604-01
studies (human)
* ROlHL-22667-01 Mechanisms of baroreceptor adaptation
in hypertension (dogs)
R23HL-22747-01 Cardiodynamics and hypertension under
cerebellar control (dogs)
ROlHL-22802-01 A rural mining community hypertension
control project (human)
ROlHL-22809-01 Coronary-prone behavior and
cardiovascular reactivity (human)
* ROlHL-22821-01 A routine screening analysis for
myoglobinemia
* ROlHL-22852-01 Diagnostic techniques in venous
thromboembolism (human)
(contd)
A prospective study-Blood pressure in
Cardiovascular aging in young men and
Behavioral treatment of Raynaud's
Non-invasive system for arteriosclerosis
'Excludes routine melhodotogy OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
CAR
ROIHI ;28b4 01 Nan invaslva blood pcessutt
mMSUttmtnt (rtls)
Bahavoilil tpptoachtj lo adoloconl
MKhanlsms ol hypertansion (humdn.
Quantltatlv* tidlocatdiography (human,
Lipid resaarch clinic
Lipid rasaarch clinic (human)
Eslablishmant ol a lipid rasaarch clinic
Lipid rasaarch clinic
Eslablishmant ot a lipid rasaarch clinic
Therapy lor hypertension In the seneral
R18HL 2293401
hyparlansion
R01HL232010I
lats)
ROIHL 23983 01
do|s)
N01HVI21S6 10
NOIHV 12157 14
N01HV121S8 10
NOIHV 12 1 S9 09
NOIHV 1216015
NOIHV 12434 11
population
NOIHV 12436 15 Hypertension therapy in the general
population (human)
NOIHV'12442 14 Therapy tor hypertension in the general
population (human)
NOIHV'22913'09 Lipid research clinic
Establishment of a lipid research clinic
Establishment of lipid research clinic
Establishment of a lipid research clinic
Lipid research clinic (human)
Establishment of u lipid research clinic
Prevention of coronary heart disease
•♦ N01HV2291408
•* N01HV2291511
" N01HV2291616
NOlHV-22917 11
NOIHV 2293209
N01HV-2297I07
(human)
NOIHV 2297607 Multiple risk factor intervention trial.
prevention of coronary heart disease
NOIHV'22980'06 Intervention trial for the prevention of
coronary heart disease (human)
NOIHV 2298207 Intervention trial for prevention of
coronary heart disease (human)
NOIHV 2298307 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-32931-09 Establishment of a lipid research clinic
center
** NOlHV-32933-07 Hypertension detection and follow-up
program central laboratory (human)
NOlHV-33101-06 Development and conduct of a multiple
risk factor intervention trial (human)
NOlHV-3310509 Intervention trial for prevention of
coronary heart disease (human)
NOlHV-3310606 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-33108-04 Prevention of coronary heart disease
(human)
** NO lHV-33 109-04 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-331 10-04 Prevention of coronarv heart disease
(human)
NOlHV-42929-08 Risk factor Intervention trial for the
prevention of CHO (human)
NOlHV-42930-09 Risk factor intervention trial for the
prevention of CHD (human)
NOlHV-42931-07 Risk factor intervention trail for the
prevention of CHD (men)
** NOlHV-52966-01 Development and evaluation of an
ultrasonic Imaging system (swine)
** NOlHV-53015-09 Establishment of a lipid research clinic
(human)
N01HV-62969-03 Cardiology patient simulator evaluation
** NOlHV-72924-04 Non-Invasive detection of atherosclerotic
lesions (human, animals)
** NOlHV-72925-04 Non-Invasive detection of atherosclerotic
lesions (human, monkeys, dogs)
NOlHV-72926-04 Ultrasonic imaging development
** NOlHV-72929-01 Improved detection of atherosclerosis
(human, dogs)
** NOlHV-72931-02 Non-Invasive detection of atherosclerotic
lesions (human, dogs)
** NOlHV-72932-00 Non-invasive detection of atherosclerotic
lesions (human, phantoms)
** NOlHV-82915-01 Therapy for hypertension In the general
population (human)
CARDIOVASCULAR DISORDERS DIAGNOSIS,
BLOOD FLOW MEASUREMENTS*
POlHL-0528518 0128 Cardiovascular-respiratory
physiology and biochemistry Pulmonary circulation in fetal
lambs in utero
POlHL-06285-18 0129 Cardiovascular-respiratory
physiology and biochemistry - Pulmonary microcirculation In
the fetus and neonate (lambs)
POlHL-06285-18 0130 Cardiovascular-respiratory
physiology and biochemistry - Ductus arterlosus-
Morphological development (human, lambs)
POlHL-06285 18 0131 Cardiovascular-respiratory
physiology and biochemistry - Fetal heart development and
ventricular outflow obstruction (lambs)
POlHL-06285-18 0133 Cardiovascular-respiratory
physiology and biochemistry - Decreased uterine blood flow
and fetal development (lambs)
POlHL-06285-18 0135 Cardiovascular-respiratory
physiology and biochemistry - Beta-adrenergic agents and
fetal cardiovascular dynamics (lambs)
** POlHL-13737-07 0013 Assisted circulation ■ Incorporation
of sensors (human, dogs)
" POlHL-1373707 0037 Assisted circulation Clinical
measurement of blood flow through aorto-coronary vein
bypass graft
Accurate transcutaneous Doppler blood
107
** PbOHl 14192 08 0008 Speciali/ed centei ol leiitarch in
hypertension New radiographic methods Recoinilion ot
renovascular hypertension (human, dog)
POIHI 14388 07 0218 Regulation ol the circulation In
pathological stales Regional myocardial dyskinesis Cause
assessment and reduction (dogs)
ROIHL 15016 07 New concepts In cardiac ultrasound
technology (human)
" ROIKL 16830 05 Non invasive determination ol aortic
blood velocities (human)
P50HL 17651 04 0032 Ischemic heart disease specialiied
center of research Cardiovascular surgery core (human,
dogs)
" ROIHL 18947 02 Indirect mean arterial pressure
(mammals)
** ROIHL 19019 03
flow monitoring
** ROIHL 19289 03 Assessment of infusion methods for
myocardial mapping (dogs)
ROIHL 2067702 Radionuclide studies in congenital heart
disease
ROIHL 20895-03 0001 Cineangiographic studies of
cardiovascular system Videodensitometry and valvular
regurgitation (human, dogs)
** ROIHL 20895-03 0002 Cineangiographic studies of
cardiovascular system Coronary disease Regional
myocardial blood flow (human, dog)
ROIHL'20943 02 Comparision of microsphere and RBC
behavior in vivo
•* ROlHL-20979-02 A novel pulsed Doppler flowmeter (dogs)
** P50HL-2I006-02 0005 Specialized center of research in
arteriosclerosis - Regional myocardial perfusion In patient
with coronary artery disease (also dogs)
ROIHL 22338-01 Platelet adhesion and aggregation in a
flow chamber (human)
CARDIOVASCULAR DISORDERS DIAGNOSIS,
BLOOD FLOW MEASUREMENTS,
ELECTROMAGNETIC*
R01HL03181-21 0020 Hemodynamics as applied to
surgical problems - Blood flow measurement -Cardiac
output and regional flows (dogs)
** ROlHL-03181-21 0029 Hemodynamics as applied to
surgical problems - Indocyanine green clearance for
estimation of hepatic blood flow (human)
POlHL-06285-18 0125 Cardiovascular-respiratory
physiology and biochemistry - Myocardial function in the
fetal and neonatal lamb
POlHL-06285-18 0128 Cardiovascular-respiratory
physiology and biochemistry - Pulmonary circulation In fetal
lambs in utero
ROlHL-13257-09 Inhalation anesthesia on myocardial
metabolism (dogs, swine, human)
** ROlHL-15781-06 Guided vascular obliteration of CNS
vascular lesions (human)
** ROlHL-17591-03 Development of electromagnetic
rheoangiography (human, dogs)
ROlHL-21796-01 Applied pulsatile hemodynamics in
vascular surgery (dogs)
ROlHL-2232101 Cardiac output from the
pneumocardiogram (dogs)
CARDIOVASCULAR DISORDERS DIAGNOSIS,
BLOOD FLOW MEASUREMENTS, HYDROGEN*
ROlHL-03181-21 0020 Hemodynamics as applied to
surgical problems - Blood flow measurement-Cardiac
output and regional flows (dogs)
CARDIOVASCULAR DISORDERS DIAGNOSIS,
BLOOD FLOW MEASUREMENTS, THERMAL*
** POlHL-1 13 10-12 0066 Mechanisms of cardiovascular
disease - Measurement of cardiac output by thermodllutlon
(children)
POlHL-11310-12 0080 Mechanisms of cardiovascular
disease - Metabolism of the hypertrophled myocardium
(human)
ROlHL-147 17-06 Hemodynamics and heart structure -
Ventricular overload (dogs)
P50HL-17651-04 0023 Ischemic heart disease specialized
center of research - Development of multipurpose catheter
for monitoring and electronic pacing
** P50HL-17651-04 0037 Ischemic heart disease specialized
center of research - Measurement of coronary venous
outflow by thermodllutlon (human)
PSOHL-17651-04 0038 Ischemic heart disease specialized
center of research - Cardlothermography (human, dog)
ROIHL- 189 33-03 Energy output and efficiency of left
ventricle (dog)
CARDIOVASCULAR DISORDERS DIAGNOSIS,
BLOOD FLOW MEASUREMENTS, ULTRASONIC*
** ROlHL-11717-09 Effect of stenotic obstructions on flow In
arteries (dogs)
** R01HL14645-07 Blood flow measurement by ultrasonic
catheter tip methods (human, dogs)
ROlHL-1478507 Ultrasonic scattering for tissue
characterization (dogs, cattle, human)
** ROlHL-16759-05 Ultrasonic measurement of cardiac
geometry and flow
P60HL-17269-04 0026 National heart and blood vessel
research and demonstration center - Dynamics of Ischemic
heart disease (human, dog)
CAR
KOIHI 1894/02 Indirect mttn •rterial pietiurt
(mammalt)
" flOlHI 189/7 03 Non Inviilvi diainotii ol p«riphiitl
arterial disease (human, dogt)
P50HI 19153 02 0001 SCOR Pulmonary edema* (dolofr.
pathogenetii Prottaglandint and Iht lung circulation
(sheep)
" ROIHI 19341 03 Ultrasonic detection of the atheroiclefolK
plaque
*• ROIHI 19406 03 Grading of atheroscleiotu by CW doppler
ultrasound (human, dogs)
" ROIHL 19791 0? Ultrasonic monitoring visceral blood
vessels
•• ROIHL 20630 03 Development of a pulsed Doppler velocity
detector (human, animals)
*• ROIHL 2083502 Signal analysis of turbulence study m
blood
•• ROIHL 2089802 Ultrasonic evaluation in direct arterial
surgery (models, cattle, human)
** ROIHL 2232601 Noninvasive measurement of cardiac
output (dogs)
** R01HL22512 01 Ultrasonic instrumentation for
cardiovascular studies
•* ROIHL 22893 01 Evaluating arterial disease by velocity-
wave analysis (dogs, human)
NOIHV 72928-04 Develop high resolution ultrasonic
Imaging techniques
** NOIHV-72929-01 Improved detection of atherotclerodi
(human, dogs)
CARDIOVAS
BLOOD P|KgW?fcftMB»iT,«fiJW«KE*
** ROlHL-2179601 Applied pulsatile hemodynamics in
vascular surgery (dogs)
CARDIOVASCULAR DISORDERS DIAGNOSIS,
CATHETERIZATION*
** ROIHL 15781-06 Guided vascular obliteration of CNS
vascular lesions (human)
ROlHL-18873-02 Early radiologic diagnosis of cardiac
failure (monkey)
CARDIOVASCULAR DISORDERS DIAGNOSIS,
EXERCISE STRESS TESTING*
POlHL-06285-18 0156 Cardiovascular-respiratory
physiology and biochemistry - Myocardial performance
following revascularization (human)
M POlHL-06296-18 Cardiovascular and pulmonary
adaptation to stress
Cardiovascular and pulmonary
Human exercise studies (human,
Cardiovascular and pulmonary
Regulation of ventricular
P01HL06296-18 0003
adaptation to stress -
dogs)
POlHL-06296-18 0005
adaptation to stress
performance (animals)
POlHL-06296-18 0007 Cardiovascular and pulmonary
adaptation to stress - Cardiovascular control during
isometric exercise (cats)
POlHL-06308-18 0010 Mechanisms and therapy of
circulatory disease - Ventricular arrhythmias during exercise
to CHD and myocardial ischemia (human)
POlHL-06308-18 0043 Mechanisms and therapy of
circulatory disease - Exercise and echocardlographic
examining techniques (human)
POlHL-06312-17 0013 Surgical cardiology - Aortocoronary
vein bypass grafting (human)
POlHL-07896-15 0061 Environmental biomedical research
program - Oxygen cost of breathing during graded exercise
(human)
POlHL-10436-13 0001 A multidisclpllnary study of
congenital heart disease - Assessment of the outlook for
children with congenital heart disease
POlHL-10436-13 0005 A multidisclpllnary study of
congenital heart disease - Pulmonary physiology in
congenital heart disease (human)
POlHL-10539-12 Pathophysiology of circulation
POlHL-10539-12 0064 Pathophysiology of circulation -
Exercise physiology and pathophysiology (human)
POlHL-11310-12 0092 Mechanisms of cardiovascular
disease - Exercise electrophysiology (human)
ROlHL-12415-10 Evaluation of left ventricular function
(dogs, rabbits)
POlHL-12738-10 0117 Physiologic pharmacology and its
clinical applications - Ventricular arrhythmias in ischemic
heart disease (human)
POlHL-13108-09 0008 Clinical heart transplantation -
Physiology and pharmacology of the transplanted human
heart
POlHL-13108-09 0024 Clinical heart transplantation -
Response of denervated heart to stress-Nonlnvaslve
(human)
POlHL-13480-09 0028 Cardiac electrophysiology - Stress
electrocardiography (human, dogs)
ROlHL-13639-07 Factors altering the course of myocardial
dysfunction (cats)
R01HL-13654-08 Antilipemic regimes In peripheral
arteriosclerosis (human)
POlHL-13738-08 0002 Cardiac assist devices and
artificial hearts - Total replacement with artificial heart
(calves, sheep, ponies)
ROlHL-14102-07 Human physiology at 5360 meters-
Mountain environment
(contd)
*Exdu(le$ routine methodotogy OR covers only general projects which preclude indexing at the speclhc level.
**Orieiited significantly to above subject.
M Grant has subprojects descritilng specific research aspects.
See Appendix for investigator's name and grant number.
CAR
108
CAR
P50HL14236-05 0007 Prevention of premature
arteriosclerosis Exercise stress testing
hyperlipoproteinemia (human)
ROlHL-15047-06 Digital computer analysis of the
electrocardiogram (human)
POlHL-15265-05 0011 Program on surgical control of the
hyperlipidemias - Central electrocardiography laboratory
(human)
POlHL-15265-05 0013 Program on surgical control of the
hyperlipidemias - Clinical center • Minnesota
P50HL-15389 07 0016 Pulmonary SCOR -Hypersensitivity
pneumonitis - Pulmonary physiology core (human)
** R01HL17246-03 Oxygen uptake at one minute of exercise
(human)
P60HL-17269-04 0027 National heart and blood vessel
research and demonstration center ■ Non-invasive
evaluation of cardiac function -Ischemic heart disease
(human, dog)
** ROlHL-17578-04 Exercise performance in children with
heart disease
P50HL-1 7648-04 0006 , Study of Ischemic heart disease -
Ventricular performance and myocardial perfusion in
obstructive coronary disease
P50HL-17651-04 0048 Ischemic heart disease specialized
center of research - Non invasive detection of ischemic
heart disease
** P50HL-1 7669-04 0008 Ischemic heart disease center
(SCOR) - Segmental ventricular dysfunction during stress-
induced ischemia (dog, human)
** P50HL-1766904 0013 Ischemic heart disease center
(SCOR) - Exercise in patients with ischemic heart disease
P50HL-17670-04 0015 Study of ischemic heart disease -
Radionuclide studies of myocardial ischemia (human)
P50HL-17670-04 0020 Study of ischemic heart disease -
Radionuclide evaluation of coronary artery disease (human,
dog)
P50HL- 17682-04 0016 Study of ischemic heart disease -
Endurance exercise -Prevention and rehabilitation in
ischemic heart disease (pig)
ROlHL-17705-04 Kallikrein-kinin system in hypertension
(human, rats, dogs)
** ROlHL-17853-03 Peripheral circulation in heart failure
(animals)
** ROlHL-18060-04 Exercise and coronary atherosclerotic
heart disease (monkeys)
ROlHL-18454-03 Maximal exercise testing in
hyperlipidemic children
ROlHL-18492-03 Measurement of regional coronary flow
reserve (human, dogs)
ROlHL-18749-03 Ventricular mechanics in the overloaded
heart (dogs)
** ROlHL-18805-04 0001 Sudden cardiac death and the
onset of myocardial infarction - Predictive value of
maximum exercise stress testing (human)
ROlHL-18984-01 P50 effect on exercise limit in stable
angina (human)
ROlHL-19343-03 Behavioral influences on cardiac
contractility (monkeys)
ROlHL-19425-03 Cardiac function in hypertrophy (dog)
M ROlHL-19451-03 Functional characteristics of the left
heart
ROlHL-19451-03 0003 Functional characteristics of the
left heart - Left ventricular segmental contraction (human.
dogs)
ROlHL-19451-03 0004 Functional characteristics of the
left heart - Quantitative coronary arteriography (human)
** ROlHL-19870-03 Hypertensive progeny -Physical and
humoral precursor search
ROlHL-20190-02 Pathogenesis of cardiac hypertrophy
(dogs)
** ROlHL-20253-02 Effects of exercise on the heart and its
blood supply (dogs)
ROlHL-20572-02 0007 Hemodynamic relations to
metabolism in hypertension - Drug effects on cardiac
function and hypertropy (rats)
ROlHL-20598-03 The coronary vascular response to
ischemia (dogs, pigs)
ROlHL-20678-02 Cardiovascular adaptation to stress in
disease states (dogs)
NOlHV-12157-14 Lipid research chnic (human)
NOlHV-22915-11 Establishment of lipid research clinic
NOlHV-22916-16 Establishment of a lipid research clinic
NOlHV-22932-09 Establishment of a lipid research clinic
N01HV-429n-07 ECG center for prevention of coronary
heart disease (human)
NOlHV-62960-00 Techniques to protect ischemic
myocardium and minimize infant size (human)
NOIHV 72939-01 Develop and evaluate left heart assist
blood pumps (human, calves, pigs)
CARDIOVASCULAR DISORDERS DIAGNOSIS,
INDICATOR DILUTION (CONCENTRATION)*
ROlHL-03181 21 0020 Hemodynamics as applied to
surgical problems Blood flow measurement-Cardiac
output and regional flows (dogs)
POlHL-04664-18 0005 Cardiovascular and lung dynamics
- Applications of current research, equipment and
techniques
** POlHL-06312-17 0047 Surgical cardiology Myocardial
extravascular water (dogs)
** ROlHL-12879-09 0006 Pulmonary transport and
metabolism in vivo - The missing sodium
ROlHL-12974-10 Tracer kinetics, flows and masses In
body organs (human, dogs)
ROlHL-19135-04 Heterogeneity of regional myocardial
blood flow (dogs)
ROlHL-19 139-03 Dispersion of diffusible indicators in the
body (human, cats, dogs)
M P50HL-19153-02 SCOR-Pulmonary edemas -Eitology,
pathogenesis
** P50HL-191 53-02 0004 SCOR -Pulmonary edemas-Eitology,
pathogenesis - Physical mechanisms in lung transvascular
transport-Math models (sheep)
** P50HL-19153-02 0005 SCOR-Pulmonarv edemas -Eitology,
pathogenesis - Lung vascular permeability measured by
indicator dilution methods (sheep)
** P50HL-19153 02 0006 SCOR -Pulmonary edemas-Eitology,
pathogenesis - Pulmonary vascular abnormalities in human
lung diseases
CARDIOVASCULAR DISORDERS DIAGNOSIS,
PLETHYSMOGRAPHY*
ROlHL-03181-21 0020 Hemodynamics as applied to
surgical problems - Blood flow measurement -Cardiac
output and regional flows (dogs)
POlHL-06296-18 0002 Cardiovascular and pulmonary
adaptation to stress - Respiratory muscle blood flow,
mechanics and metabolism (human, dog)
** P01HL-14580-07 0005 Program project in respiratory
mechanics - Development and evaluation of tests of
pulmonary function (human)
ROlHL-16463-05 Localization of airways obstruction and
responses
** ROlHL-19038-02 Plethysmographic evaluation of carotid
blood flow (human, rabbits, dogs)
ROlHL-22852-01 Diagnostic techniques in venous
thromboembolism (human)
N01HR-62901-04 Measure pulmonary function in infants
and children (also dogs, rabbits)
CARDIOVASCULAR DISORDERS DIAGNOSIS,
PLETHYSMOGRAPHY, PHOTOELECTRIC*
** ROlHL-19038-02 Plethysmographic evaluation of carotid
blood flow (human, rabbits, dogs)
CARDIOVASCULAR DISORDERS DIAGNOSIS,
SOUND MEASUREMENTS, VASCULAR*
SEE ALSO HEART DISORDERS DIAGNOSIS, HEART SOUND
MEASUREMENTS*
ROlHL-16830-05 Non-invasive determination of aortic
blood velocities (human)
ROlHL-22783-01 Hemodynamic induction of intimal
fibromuscular lesion
CARDIOVASCULAR DISORDERS EPIDEMIOLOGY
ROlHL-01979-22 Arteriosclerosis in zoo animals on
controlled diets (animals)
** ROlHL-03341-22 Epidemiology of atherosclerosis in Evans
Co Georgia
'* ROlHL-03429-18 Central nervous system and coronary
heart disease (human)
** ROlHL-04697-17 International heart disease epidemiology
(human)
M POlHL-08974-14 Natural and experimental atherosclerosis
POlHL-08974-14 0005 Natural and experimental
atherosclerosis - Atherosclerosis, coronary heart disease
and sudden death (human)
** POlHL-090 11-15 0018 A research and resource program
in blood - Hepatitis B in normal populations-Epidemiology,
risk factors and transmission
POlHL-10436-13 0001 A multidisciplinary study of
congenital heart disease - Assessment of the outlook for
children with congenital heart disease
POlHL-113 10-12 0091 Mechanisms of cardiovascular
disease - Noninvasive techniques in cardiovascular
diagnosis (human)
ROlHL-1 1901-12 0009 Effects of metabolic surgery on
the hypertipidemias - Cholesterol cord blood and family
management program
** ROlHL-13974-07 Ventricular premature beats and sudden
coronary death (human)
P50HL-14141-05 0001 SCOR for atherosclerosis in
childhood - Clinical implications (infants and children)
** P50HL-14141-05 0002 SCOR for atherosclerosis in
childhood - Intrauterine environment of proband group
(human)
** ROlHL-14148-07 0007 The regional circulations - Salivary
composition in hypertension (human)
** P50HL-141 59-08 0021 Specialized center of research in
hypertension - Genetic studies of the physiology of
hypertension (human, rats)
** P50HL-14230-07 0088 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Coronary risk factors in school children-
The Muscatine study
P50HL-14236-05 0001 Prevention of premature
arteriosclerosis - Metabolism and transport of cholesterol
and vitamin A (human, rats)
** P50HL-14237-07 0005 Support for arteriosclerosis center
- Genetic determinants of apolipoprotein variability in
lipoproteins (human)
POlHL-14388-07 9004 Regulation of the circulation in
pathological states - Core biostatistics unit
ROlHL-15047-06 Digital computer analysis of the
electrocardiogram (human)
P50HL-15103-07 A/S SCOR-Early natural history of
arteriosclerosis
P50HL-15103-07 0001 A/S SCOR-Early natural history of
arteriosclerosis • Clinical research -Bogalusa heart study
(children)
ROlHL-15174-06 CV disease epidemiology-Second
generation studies (human)
ROlHL-15191-07 Multiparameter methods for
cardiovascular research
ROlHL-15614-04 Heredity and oxygen-Effects on health of
heart-lungs (South America)
ROIHL- 15790-06 Follow-up study of acute coronary heart
attacks (human)
ROlHL-16403-05 Prognostication by computer -Analyzed
vectorcardiogram (human)
ROlHL-16461-05 Late results of valve replacement-
Computer analysis (human)
ROlHL-16484-04 Radiographic ventriculometry for coronary
heart disease (human)
ROlHL-16774-04 Genetic epidemiology of hyperlipemia
(Honolulu)
ROlHL-16908-04 Myocardial function, risk factors and
future CHD (men)
ROlHL-16909-04 Myocardial function, risk factors and
future CHO (men)
P60HL-17269-04 0039 National heart and blood vessel
research and demonstration center - Health care services
to patients in neighborhood clinics
ROlHL-17408-03 Fresh blood rheology-Relation to
cardiovascular risk (human)
ROIHL 17580-04 The impact of stress on coronary heart
disease (men)
' P50HL-17667-04 0001 Study of ischemic heart disease -
Natural history of ischemic heart disease (human)
' P50HL- 17669-04 0013 Ischemic heart disease center
(SCOR) - Exercise in patients with ischemic heart disease
■ P50HL-17670-04 0012 Study of ischemic heart disease -
Epidemiology of sudden death (human)
ROlHL-18175-03 Drug taking for hypertension in a njral
community
' ROlHL-18235-03 Cardiovascular fitness and other risk
factors (human)
' P50HL-18318-03 0012 Pathogenesis and complications of
hypertension - Behavioral factors in hypertension (human)
P50HL-18318-03 0018 Pathogenesis and complications of
hypertension - Plasma renin activity in chronic ischemic
heart disease (human)
P50HL-18323-04 0011 SCOR hypertension center -
Endocrine profiling on a selected normal population
(human)
P50HL-18323-04 0035 SCOR hypertension center - Control
of high blood pressure at the work site
R25HL-18406-03 Adherence to hypertensive medical
regimens (human)
R25HL-18414-03 Hypertension-Family strategies for
patient adherence
R25HL-18418-03 Role of a supporting partner in
adherence (human)
R25HL-18424-03
setting (human)
* ROlHL-18456-03
Blood pressure education in an industrial
Cardiovascular follow-up of hypertensive
adolescents
ROlHL-18535-03 Epidemiology and course of viral
myopericarditis (human)
ROlHL-18589-03 Psychosocial factors and outcome in
coronary disease (human)
ROlHL-18683-03 Left ventricle function in aortic
regurgitation (human)
ROlHL-18715-02 Hypertension incidence project (human)
ROlHL-18769-04 Studies in survivors of lethal arrhythmias
(human)
ROlHL-18776-04 Prevention of acute and fatal
cardiovascular disease (human)
ROlHL-18783-04 Detection and control of ventricular
premature beats (human)
ROlHL-18793-03 Clinical-pathologic studies of sudden
cardiac death (human)
ROlHL-18800-04 Prospective study of resuscitated sudden
death victims (human)
ROlHL-18805-04 Sudden cardiac death and the onset of
myocardial infarction
ROlHL-18805-04 0001 Sudden cardiac death and the
onset of myocardial infarction - Predictive value of
maximum exercise stress testing (human)
ROlHL-18805-04 0003 Sudden cardiac death and the
onset of myocardial infarction - Prediction from clinical and
laboratory assessments (human)
ROlHL-18808-04 0001 Prediction and prevention o,
sudden cardiac death - Prognostic significance of
premature ventricular contractions (human)
ROIHL 18850 03 Classification code for Frank orthogonal
ECG
ROlHL-18907-03 Objective evaluation early after Ml and
heart surgery (human)
ROlHL-19073-02
home
ROlHL-1956703
Heart disease and drinking water at
Impact of emotion on coronary arteries
(human)
ROlHL-19839-09 Factors in youth predisposing to chronic
diseases (former college students)
ROlHL-19858-03 UMMC -Blood pressure precursors and
consequences (human)
(contd)
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
••Qnented significarrtly to above subject
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
CAR
109
CAR
High blood pressure in young people in
ROIHL 198b9 03 Epldemiolo|lcil studies, precursors of
hypertension (humin)
ROIHL 19864 03 Blood pressure ol children and young
adults
ROIHL 19864 03 0001 Blood pressure ol children end
young adults Follow up ol students Iram Dormont
Pennsylvania
ROIHL 19864 03 0002 Blood pressure ot children and
young adults Data epidemiology center
ROIHL 19869 03 Antecedents ol adolescent hypertension
(human)
ROIHL 198/; 02 Prevention ot high blood pressure in
children
ROIHL 19929 03 High blood pressure in the young,
prevalence and precursors (human)
ROIHL I99S6 03 High blood pressure in the young
(human)
ROIHL 1996203
Tecumseh
ROIHL 19984 02 Blood pressure and immunogenetic
tactors in the young (human)
ROIHL 20124 02 Coronary risk lactors (human)
ROIHL 20159 03 Genetic epidemiology ol precursors ot
hypertension (human)
ROIHL 201/9 02 Epidemiology ol sudden cardiac death
among women
ROIHL 20244 02 he impact ot hypertension inlormation
ROIHL-20245 01 The impact ol hypertension inlormation
ROIHL 20247-01 The impact ol hypertension inlormation
ROlHL-20248-01 The impact ol hypertension inlormation
ROIHL 20374 03 Myocardial lunction Risk lactors and
luture CHO (human)
ROIHL 20418-03 Serum cholesterol binding reserve in
diabetes (human)
R01HL20508-03 Diabetes, hyperglycemia and
cardiovascular disease (human)
ROIHL-20522-03 Peripheral arterial disease in the diabetic
(human)
R0IHL-2053S-02 Cardiovascular disease and evolving
diabetes mellitus (human)
ROIHL-20637-02 Recovery alter heart surgery-Bio-
behavioral lactors (human)
ROlHL-2065502 Autonomic predictors ol hypertension in
children
ROlHL-20662-02 Physical activity, litness and
epidemiology ol CHD
ROlHL-20724-01 Behavioral consequences ol hypertension
(human)
ROlHL-21010-02
40.000 persons
ROlHL-21039-02
Indians
ROlHL-21088-02
stroke in Utah
ROlHL-21307-01
population
ROlHL-21427-02
patients
ROlHL-21527-01
(human)
R18HL-2190601
reduction study
ROlHL-21971-01
in twins (human)
ROlHL-21985-01
disease
ROlHL-222 12-01
control program
R01HL-22255-01
NOIHV 12440 14 Iherapy lor hypertension in the general
population (human)
NUIHV 12442 14 Iherapy lor hypertension in the general
population (human)
Glycemia. other traits and CV death in
Vascular lesions ol diabetes in Oklahoma
Genetic patterns in deaths Irom Ml and
Risk reduction and exercise litness in a
Behavioral changes in post intarction
Prospective study ol bundle branch block
Stanlord live city multilactor risk
Atherosclerotic disease and risk lactors
Videoroentgenography in congenital heart
Alameda county high blood pressure
Behavior patterns, stress, and
Behavioral treatment cl Raynaud's
The etiology/prevalence ol peripheral
arterial disease (human)
ROlHL-22298-02 Origins ol hypertension (human)
ROIHL-22378-01 Psyco-somatic predictors ol CHD in
adolescence (human)
ROlHL-22380-01 Detroit hypertension control program
ROlHL-22472-01 Smoking risk-lactor reduction-
Maintenance strategies (human)
ROlHL-22514-01
catecholamines
ROlHL-22547-01
disease (human)
ROlHL-22802-01 A rural mining community hypertension
control project (human)
ROlHL-22809-01 Coronary-prone behavior and
cardiovascular reactivity (human)
R18HL22934-01 Behavorial approaches to adolescent
hypertension
ROIHL 2298201 Multicenter postcoronary risk
stratilication program (human)
R01HL-23078-0I Psychosocial stress and sudden coronary
death (human)
N01HV12156-10
N0IHV1215714
NOIHV1215810
NOlHV-1215909
N0IHV12160I5
NOIHV-12434-11
population
NOlHV-12435-15 Therapy lor hypertension in the general
population (human)
NOIHV- 12436- 15 Hypertension therapy in the general
population (human)
Lipid research clinic
Lipid research clinic (human)
Establishment ol a lipid research clinic
Lipid research clinic
Establishment ol a lipid research clinic
Therapy lor hypertension in the general
Lipid research clinic
Establishment ol a lipid research chnic
Lipid research clinic (human)
Establishment ol a lipid research clinic
Iherapy lor hypertension in general
NOIHV 2291309
NOIHV 229 14 08
NOIHV 2291/ 11
NOIHV 22932 09
NOIHV 2293/0/
population
NOIHV 22945 11 Coopeiative hypertension detection and
lollow up study (human)
NOIHV 229/1 07 Prevention ol coronary heart disease
(human)
NOIHV 229760/ Multiple risk lactor intervention trial.
prevention ol coronary heart disease
NOIHV 22977 08 Intervention trial lor the prevention ol
coronary heart disease (human)
NOIHV 229790/ Intervention trial lor the prevention ol
coronary heart disease (human)
NOIHV 22980 06 Intervention trial lor the prevention ol
coronary heart disease (human)
NOIHV 22981 10 Intervention trial for the prevention ol
coronary heart disease (human)
NOIHV 229820/ Intervention trial lor prevention ol
coronary heart disease (human)
NOlHV-22983-07 Intervention trial for the prevention ol
coronary heart disease (human)
NOlHV-32973-12 Coordinating center lor collaborative
studies on coronary artery surgery
NOlHV-33101-06 Development and conduct ol a multiple
risk lactor intervention trial (human)
NOlHV-3310509 Intervention trial lor prevention of
coronary heart disease (human)
NOlHV-33106-06 Intervention trial lor the prevention ol
coronary heart disease (human)
N01HV33108 04 Prevention of coronary heart disease
(human)
NOIHV 33109 04 Intervention trial lor the prevention ol
coronary heart disease (human)
NOlHV-331 10-04
(human)
NOlHV-42902-08
Prevention ol coronary heart disease
Epidemiological studies ol coronary heart
disease (human)
NOlHV-4291107 ECG center for prevention ol coronary
heart disease (human)
NOlHV-42929-08 Risk lactor intervention trial lor the
prevention ol CHD (human)
NOlHV-42930-09 Risk lactor intervention trial lor the
prevention ol CHD (human)
NOlHV-42931-07 Risk lactor intervention trail lor the
prevention ol CHD (men)
NOlHV-42933-09 Multiple risk factors in coronary heart
Establishment ol a lipid research clinic
disease (human)
** NOlHV-53015-09
(human)
** NOlHV-6295504 Data collection in clinical pathology and
morbid anatomy (men)
NOlHV-829 15-01 Therapy lor hypertension in the general
population (human)
CARDIOVASCULAR DISORDERS PREVENTION
AND CONTROL (NOT INCLUDED ELSEWHERE)
SEE ALSO CARDIOVASCULAR DISORDERS CHEMOTHERAPY
SEE ALSO CARDIOVASCULAR DISORDERS EPIDEMIOLOGY
SEE ALSO CARDIOVASCULAR SURGERY
ROlHL-01803-23 0005 Arteriosclerosis, glomerulonephritis,
rheumatic lever - Immunologic and dietary synergy in the
pathogenesis of atherosclerosis (rabbits)
POlHL-06285-18 0178 Cardiovascular-respiratory
physiology and biochemistry ■ Biochemical regulation of
hypertrophy (rats, rabbits)
** P01HL06312 17 0050 Surgical cardiology • Prevention of
pericardial and pleural adhesions by silicone oil (dogs)
** POlHL-0683517 0014 Cardiovascular disease ■ Dietary
induction ol severe atherosclerosis and its prevention
(dogs)
ROIHL 08892-10 Cooperative study ol drugs and coronary
heart disease
ROlHL-1 1686-09 Dynamics ol thrombus lormation and
dissolution (human, chickens)
M POlHL-15265-05 Program on surgical control of the
hyperlipidemias
** POlHL-15265-05 0003 Program on surgical control of the
hyperlipidemias - Central lipid laboratory
R01HL15498-06 Effects of physical training on heart
(rats)
P60HL 17269-04 0037 National heart and blood vessel
research and demonstration center • Secondary and
university education
P60HL-17269-04 0038 National heart and blood vessel
research and demonstration center - Continuing education
** P60HL-17269-04 0039 National heart and blood vessel
research and demonstration center - Health care services
to patients in neighborhood clinics
" ROlHL-17332-04 Use of the gut for therapy ol coronary
artery disease (mammals)
** ROIHL 17580-04 The impact ol stress on coronary heart
disease (men)
ROlHL-1762305 Initial events in thrombus lormation on
surlaces (human, rats)
P&OHl- 1 7UZ-04 0016 Study ol luhemic heart diiet-.a
Endurinc* IMfClM"Pravention and rehibihlalion in
iichemic heart dlMiM (pig)
ROIMI 1/809 04 rilecll ol lUtclM on the coronary
vasrulalure (rat, dog)
ROIHI 1/9/4 01 Fiternal pneumatic comprettion in deep
venous thrombosis (human)
ROIHI 18215 01 Cardiovascular lilnets and other risk
lactors (human)
PbOHl 18323 04 0035 SCOR hypertension center Control
ul high blood pressure at the work site
ROIHt 18333 05 Ihrombogenesis and hemostatic balance
(rabbits, human)
ROIHL 18/15 02 Hypertension incidence protect (human)
ROIHL 18/38 02 Prevention of posloperative venous
thrombi (human, caltle)
ROIHI 18//604 Prevention ol acute and lalal
cardiovascular disease (human)
ROIHL 18/98 04 0003 Nervous and ionic lactors in
sudden cardiac death Lett stellectomy in the prevention
ol sudden dealh (dogs)
ROIHL 1890/ 03 Ob|ective evaluation early after Ml and
heart surgery (human)
ROIHL 1935002 Prevention ol thrombosis by applied
electric lields (sheep)
ROIHL 19839 09 Factors in youth predisposing to chronic
diseases dormer college students)
Prevention ot high blood pressure in
Coronary risk lactors (human)
Atherosclerosis and diabetes mellitus
Memory alloy tillers lor venous emboli
R0IHL1987702
children
ROIHL 20124-02
ROIHL 2047103
(human)
ROIHL 20554 02
(dogs)
ROIHL 20637 02 Recovery alter heart surgery-Bio
behavioral lactors (human)
ROIHL 20910 02 The alternative diet lor coronary disease
prevention (human)
P50HL 21006-02 0001 Specialized center ol research in
arteriosclerosis - Clinic and core program
ROlHL-21039-02 Vascular lesions ol diabetes in Oklahoma
Indians
ROlHL-21307-01
population
R01HL-2I42702
patients
ROlHL-21527-01
(human)
ROlHL-21572-01
syndrome
R18HL-2 1 906-01
reduction study
ROlHL-21912-01 Biosynthesis ol lipoic acid and
atherosclerosis (birds, chick embryos)
ROIHL-2209801 Is postoperative inlarction due to
reperfusion injury? (human, dogs)
R01HL-222I2-01 Alameda county high blood pressure
control program
R23HL-2234502 Behavioral cardiovascular compliance
strategies
Behavioral cardiovascular
Long term modification ol dietary
Risk reduction and exercise litness in a
Behavioral changes in post inlarction
Prospective study ol bundle branch block
Natural history of the postphlebific
Stanlord live city multilactor risk
R23HL-22345-02 0001
compliance strategies
patterns (human)
R23HL-22345-02 0002
compliance strategies
'Excludes mcHne me(hodok)gy OR covers only general projects which preclude indexing
•*0nented signrficantly to above subject.
Behavioral cardiovascular
Compliance with antihypertensive
medication regimens (human)
** ROlHL-22380-01 Detroit hypertension control program
** ROlHL-22573-01 Treatment ol post surgical
vasoconstriction (dogs, monkeys, human, rats)
** R01HL-22759-01 Regional myocardial blood flow during
hypothermia (dogs)
** ROlHL-22802-01 A rural mining community hypertension
control project (human)
ROlHL-22821-01 A routine screening analysis for
myoglobinemia
ROlHL-22852-01 Diagnostic techniques in venous
thromboembolism (human)
** ROlHL-2288801 Prosthetic valve endocarditis -Etiology
and therapy (dogs)
R18HL-22934-01 Behavorial approaches to adolescent
hypertension
** ROlHL-2298201 Multicenter postcoronary risk
stratification program (human)
NOlHV-62941-01 Nutrition coding center for MRFIT and
LRC programs
CARDIOVASCULAR EXAMINATIONS
SEE CARDIOVASCULAR DISORDERS DIAGNOSIS*
CARDIOVASCULAR FUNCTION
SEE ALSO CARDIOVASCULAR SYSTEM, BLOOD SUPPLY
SEE ALSO CARDIOVASCULAR SYSTEM, ENDOTHELIUM
PERMEABILITY
SEE ALSO HEART FUNCTION
ROIHL 02363 20 Kinetics ol water and electrolytes in
shock (dogs, rats)
POlHL-0628518 Cardiovascular-respiratory physiology and
biochemistry
POlHL-06285-18 0136 Cardiovascular-respiratory
physiology and biochemistry - Fetal microcirculation in
utero (rabbits, lambs)
P01HL06835-17 Cardiovascular disease
POlHL-08682-15 Regulation ol the cardiovascular system
(contd)
M
at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
CAR
POlHL-0868215 0025 Regulation of the cardiovascular
system - Physiology of preganglionic cell bodies (cat)
M POIHLI 1678-11 Cardiovascular dynamics and their
control
POIHLI 1678-11 0017 Cardiovascular dynamics and their
control - Overall control of circulation -Mathematical
analyses
** POlHL-12373-10 0014 Cardiopulmonary physiology and
pathophysiology - Analog digital computation and
simulation facility
POlHL-12373-10 0019 Cardiopulmonary physiology and
pathophysiology • Free ranging animal facility
ROIHL 13187-09 Central neural control of cardiovascular
function (cats)
POlHL-14388-07 0156 Regulation of the circulation in
pathological states - Blood pressure with drinking to
intracranial angiotensin II injections (rats)
POlHL-14388-07 0158 Regulation of the circulation in
pathological states - Developmental aspect of abnormal
vascular reactivity (rats)
** POlHL-14414-07 0015 Environmental influences on
cardiorespiratory and cellular functions - Control of the
cardiovascular system (dogs)
** ROlHL-14693-07 Survival value of physiological responses
to hypoxia (dogs)
** P60HL-1 51 58-07 0025 Comprehensive sickle cell center -
Cardiovascular evaluation of children with sickle cell
disease (human)
ROlHL-15676-06 The role of occult myocardial failure in
human shock (human, dogs)
M POlHL-16117-05 Ion movements and membranes in
cardiovascular control
** ROlHL-16390-05 Cardiopulmonary control coupling in
exercise (dogs)
** ROlHL-16648-16 Integrated control of cardiovascular
activity (cats)
ROlHL-167 14-05 Endothelial cell communication in
homeostasis (human, mammals)
** ROlHL-17629-03 Developmental aspects of cardiovascular
function (human, cats, rabbits)
** ROlHL-17847-04 Cardiovascular and renal functions of
marmots
** ROlHL-18560-03 Cardiovascular adaptation to stress
(miniature swine)
** POlHL-18974-03 0001 Experimental neurogenic
hypertension program - Central neural systems regulating
arterial pressure (rabbits)
** ROlHL-19057-03 Catecholamines and cyclic AMP in
cardiovascular system (rats, dogs)
** ROlHL-19680-01 Cardiac correlates of behavioral stress in
animals (dog)
** ROlHL-20373-02 Cardiovascular aging in young men and
women
ROlHL-21117-01 Altitude adaptation in chronic lung
disease (human)
** ROlHL-21532-02 Cardiovascular homeostasis and learning
(frogs, rats, human)
** ROlHL-21673-01 Pathophysiology of venous changes in
hypertension (rats, rabbits, human, dogs)
R23HL-21954-01 Exercise conditioning in patients with
cystic fibrosis
** ROlHL-2 1985-01 Videoroentgenography in congenital heart
disease
** ROlHL-22715-01 Neural integration of the cardiovascular
reflexes (dogs))
CARDIOVASCULAR FUNCTION, BLOOD
CIRCULATION DYNAMICS (GENERAL)
SEE ALSO CEREBROVASCULAR SYSTEM, BRAIN CIRCULATION
** ROlHL-01755-25 Fetal and neonatal cardiovascular
function (sheep)
** ROlHL-02228-24 Respiration, circulation, and heat
regulation in exercise (bird, mammals)
** ROlHL-02888-22 Interrelationships of circulation and
respiration (opossum, cats)
M ROlHL-03181-21 Hemodynamics as applied to surgical
problems
** ROlHL-03181-21 0028 Hemodynamics as applied to
surgical problems ■ Extra-renal factors in the hypertension
of coarctation (dog)
ROlHL-03181-21 0029 Hemodynamics as applied to
surgical problems - Indocyanine green clearance for
estimation of hepatic blood flow (human)
POlHL-04664-18 0015 Cardiovascular and lung dynamics
• Computer system for the cardiovascular laboratory
ROlHL-04666-19 Artificially paced hearts-Technology,
physiology (human, dogs)
M R01HL05883-18 Reflex control of resistance and
capacitance vessels
POlHL-06285-18 0127 Cardiovascular-respiratory
physiology and biochemistry Experimental congenital
cardiac lesions in fetal lambs
•* POlHL-06285 18 0155 Cardiovascular-respiratory
physiology and biochemistry - Therapeutic alterations,
contractile state in heart failure
POlHL-06285-18 0157 Cardiovascular-respiratory
physiology and biochemistry Lett ventricle outflow
impedance analysis (human)
POlHL-06285-18 0158 Cardiovascular-respiratory
physiology and biochemistry - Load on myocardial
contractility (dogs)
110
POlHL-06285-18 0164 Cardiovascular-respiratory
physiology and biochemistry - CPK MB isoenzyme
concentration to quantify infarct size (human, animals)
** POlHL-06308-18 0012 Mechanisms and therapy of
circulatory disease - Echocardiographic evaluation of
hemodynamics of arrhythmia (human)
POlHL-06308-18 0043 Mechanisms and therapy of
circulatory disease - Exercise and echocardiographic
examining techniques (human)
POlHL-063 12-17 0046 Surgical cardiology • The
relationship of prostaglandins to heart disease
POlHL-06664-17 0010 Cardiopulmonary function in
remediable vascular disease - Ischemia and acute renal
failure (rats)
POlHL-06664-17 0034 Cardiopulmonary function in
remediable vascular disease - Role of hyperosmolar agents
in ischemic heart disease (dogs)
POlHL-06835-17 0040 Cardiovascular disease - Benign
and malignant phase of renal hypertension (dogs)
POlHL-06835-17 0048 Cardiovascular disease -
Aldosterone producing adenoma prediction of curability
(human)
** POlHL-06835-17 0051 Cardiovascular disease -
Cardiopulmonary volume in hypertension (human)
** POlHL-06835-17 0053 Cardiovascular disease -
Vasodilating drugs (human)
** ROlHL-07139-17 Cardiodynamics and metabolism of
congestive failure (human, dogs)
POlHL-07293-17 0057 Non-invasive cardiovascular
measurements - Peripheral vascular scanner engineering
evaluation and error analysis (human)
ROlHL-08659-14 Myocardial performance and metabolism
in the newborn (sheep)
** POlHL-08682-15 0021 Regulation of the cardiovascular
system - Hypoglycemia in pathogenesis of shock (dog)
ROlHL-08696-15 0020 Orthotopic heart transplantation -
Complete cardiopulmonary transplantation (dogs)
M POlHL-08805-15 Regulation of ventilation and pulmonary
circulation
POlHL-08805-15 0006 Regulation of ventilation and
pulmonary circulation - Adaptation of lungfish-Estivation
POlHL-08805-15 0049 Regulation of ventilation and
pulmonary circulation - Pulmonary hypertension produced
by Dirofilaria immitis in the dog
ROlHL-097 11-13 Instantaneous blood flow in ascending
aorta (human, dogs)
** ROlHL-10182-13 Circulatory function and electrolytic
metabolism (dogs, human)
** ROlHL-10330-11 Physiological mechanics of the heart and
arteries (dogs, rabbits, horses)
** POlHL-10342-13 0028 The integrated function of
respiration and circulation - Mediator release,
hemodynamics and respiratory function in anaphylaxis
(dogs)
ROlHL-10384-13 Blood flow and nucleotide metabolism
(animals)
POlHL-10436-13 0014 A multidisciplinary study of
congenital heart disease - Cardiovascular pharmacology
(dog)
** POlHL-10436-13 0015 A multidisciplinary study of
congenital heart disease - Fetal and neonatal
cardiovascular physiology (sheep)
ROlHL-10622-12 Volumes and compliance of pulmonary
circulation (human, dogs)
** ROlHL-10881-13 Structure and function of
microcirculation (hamsters, rats, cats, dogs)
ROlHL-10914-10 Renal sodium transport in experimental
aldosteronism (dogs)
** ROlHL-1 1289-12 Analysis of stress in pulsatile dynamics
POlHL-l 13 10-12 0056 Mechanisms of cardiovascular
disease - Cardiac output response to blood pressure
reduction in infants (human)
POlHL-l 13 10-12 0057 Mechanisms of cardiovascular
disease - Blood pressure reduction after heart surgery in
adults (human)
POlHL-l 13 10-12 0060 Mechanisms of cardiovascular
disease - Effect of left atrium on the circulation-Simulation
** POlHL-l 13 10-12 0067 Mechanisms of cardiovascular
disease - Cardiac performance with measured
hemodynamic variables (human)
** POlHL-l 13 10-12 0082 Mechanisms of cardiovascular
disease - Myocardial function in adult congenital heart
disease (human)
** POlHL-l 13 10-12 0083 Mechanisms of cardiovascular
disease - Ventricular volume and hemodynamics in adult
congenital heart disease
** POlHL-11678-11 0017 Cardiovascular dynamics and their
control Overall control of circulation-Mathematical
analyses
** POlHL-11678-11 0020 Cardiovascular dynamics and their
control - Circulatory and pulmonary fluid dynamics during
pulmonary edema
POlHL-l 1678-11 0027 Cardiovascular dynamics and their
control - Vasopressin and thirst in control of body fluid
volumes and osmolality (dogs)
** POlHL-11678-11 0043 Cardiovascular dynamics and their
control - Basic mechanisms of circulatory shock (dog)
** POlHL-11678-11 0058 Cardiovascular dynamics and their
control ■ Overall control of the circulation-Computer
analysis
** POlHL-11678-11 0059 Cardiovascular dynamics and their
control - Basic hemodynamics (dogs, rats)
CAR
POlHL-11678-11 0064 Cardiovascular dynamics and their
control - Renal medulla -Control of renal hemodynamics,
electrolyte excretion (dogs)
POlHL-11678-11 0067 Cardiovascular dynamics and their
control - Angiotension II, sodium excretion and renal
hemodynamics (dogs)
POlHL-11678-11 0068 Cardiovascular dynamics and their
control - Basic hemodynamics (rats, dogs)
POlHL-11678-11 0069 Cardiovascular dynamics and their
control - Nervous control of the cirulation (dogs)
ROlHL-11717-09 Effect of stenotic obstructions on flow in
arteries (dogs)
ROlHL-11802-10 Cardiovascular surgical research (dogs.
sheep, swine, cats, monkeys)
ROlHL-11876-11 Regional myocardial blood flow and
metabolism (dogs, swine)
ROlHL-12083-11 Flow field in aorta and its major
branches (dogs, phantom models)
POlHL-12373-10 0005 Cardiopulmonary physiology and
pathophysiology - Characterization of fetal and neonatal
myocardium (human, cats)
POlHL-12373-10 0013 Cardiopulmonary physiology and
pathophysiology - Effects of cardiovascular drugs on left
ventricular function (dogs)
' POlHL-12373-10 0015 Cardiopulmonary physiology and
pathophysiology - Cine angiographic-hemodynamic facility
ROlHL-12493-10 Bioengineering analysis of microvascular
function (cats, rabbits)
ROlHL-12494-10 Continuum mechanics in biophysics
(human, animals)
ROlHL-12677-10 Surgical physiologic studies of isolated
kidneys (dogs, rats)
' ROIHL 12690-09 Systemic and local vascular adjustment
in shock (monkeys, cats)
' ROlHL-12711-09 Mathematical approach to cardiovascular
mechanics (human, animals)
POlHL-12738-10 0069 Physiologic pharmacology and its
clinical applications - Blood rheology in coronary heart
disease (dogs)
POlHL-12738-10 0092 Physiologic pharmacology and its
clinical applications - Subendocardial ischemia following
open heart surgery (human)
POlHL-12738-10 0098 Physiologic pharmacology and its
clinical applications - Skeletal muscle support of the
chronically failing heart (dogs)
* POlHL-12738-10 0111 Physiologic pharmacology and its
clinical applications - Cardiovascular pharmacology (dogs)
POlHL-12738-10 0133 Physiologic pharmacology and its
clinical applications - Pharmacologic antagonism of beta-
adrenergic blockade (dogs)
* ROlHL-12777-09 Mechanisms in cardiac performance
(dogs, human)
ROlHL-12827-08 Regulation of sodium excretion (dogs,
rats)
POlHL-13108-09 0001 Clinical heart transplantation -
Therapy and prognosis (human)
* POlHL-13108-09 0008 Clinical heart transplantation -
Physiology and pharmacology of the transplanted human
heart
POlHL-13108-09 0'D23 Clinical heart transplantation -
Adaptive mechanisms of the denervated heart (human)
ROlHL-13257-09 Inhalation anesthesia on myocardial
metabolism (dogs, swine, human)
* POlHL-13330-08 0031 Mechanical circulatory support -
Hemodynamics of cardiac prosthesis
ROlHL-13426-09 Left ventricular bypass for myocardial
infarction (cattle, human)
ROlHL-13427-09 Neural control of blood volume (monkeys,
dogs)
ROlHL-13623-08
'* ROlHL-13634-08
ROlHL-13639-07
dysfunction (cats)
* POlHL-13737-07 Assisted circulation
POlHL-13737-07 0002 Assisted circulation
mechanical auxiliary ventricle (dogs)
'* POlHL-13737-07 0007 Assisted circulation -
Determination of cardiac status by use of balloon pump
(dogs)
POlHL-13737-07 0008 Assisted circulation - Phase-shift
balloon pumping alternate designs
" POlHL-13737-07 0009 Assisted circulation
models
POlHL-13737-07 0013 Assisted circulation - Incorporation |
of sensors (human, dogs)
POlHL-13737-07 0024 Assisted circulation
prosthetic myocardium (dogs)
POlHL-13737-07 0027 Assisted circulation
of cardiac assistance (dogs)
POlHL-13737-07 0028 Assisted circulation - Clinical
studies of intraaortic balloon pumping
POlHL-13737-07 0030 Assisted circulation
ischemia-Effects of phase-shift balloon pumping (dogs)
POlHL-13737-07 0032 Assisted circulation - The dynamic \
aortic patch (human, dogs)
POlHL-13737-07 0035 Assisted circulation - Mapping tha|
geometry and elasticity of the aorta
** POlHL-13737-07 0036 Assisted circulation - Assessment
of infarct size from hemodynamic measurements
POlHL-13737-07 0039 Assisted circulation - Computer
controlled intraortic balloon pumping
(contd)
Atrial receptors (dogs)
Renal hypertension in pregnancy (sheep)
Factors altering the course of myocardial
U-shaped
Analytical
Dynamic
Optimization I
Myocardial
•Excludes routine methodotogy OR covefs only general projects which preclude indexing at the specific level.
"Oriented significantly to »tme subject.
M Grant has subprojects descnblng specific research aspects.
See Appendix for investigator's name and grant number.
CAR
111
CAR
POIHL 13738 08 0001 Cirdlic aislst dtvlcts ind
•rIKicKl h*ir1i Citdiac isslsl d«vlc(j (human. shMpI
ROIHL 13803 07 Advanod cardiac valvulai and vascular
prosthesis (dogs, baboons)
ROIHI 1414807 0008 Th« ragional circulations Ranal
circulation in hypartansive patients (also dogs)
PSOHL 14 159 08 0021 Specialited canter o( research in
hypertension Genetic studies ol the physiology ot
hypertension (human, rats)
PSOHl 1418707 000b Pulmonary SCOR Chemical
mediators in pulmonary vascular responses Pulmonary
hypertension and cardiac (unction (dogs, human)
ROIHI 14306 07 Quantilication ot arterial pressure control
(dogs)
POIHI 14388 07 Regulation ol the circulation in
pathological states
POIHL 1438807 0151 Regulation ol the circulation in
pathological states Catecholamine release in potassium
ion tree contractures in the caudal artery
POIHL 1438807 0152 Regulation ot the circulation in
pathological states Ion llux alterations in caudal artery in
SHR
POIHL 1438807 0153
pathological states
(rats)
POIHL 1438807 0154
pathological states
contraction (rats)
POIHL 14388-07 0155
pathological states
Regulation ot the circulation in
Subcellular distribution ol calcium
Regulation ol the circulation in
Energetics ot smooth muscle
Regulation ol the circulation in
Cardiopulmonary allerent activity.
carotid chemo-baroreceptor rellexes
POIHL 1438807 0164 Regulation ol the circulation in
pathological states Hyperkinetic heart syndrome (human)
POlHL-14388-07 0165 Regulation ol the circulation in
pathological states Vascular resistance in experimental
atherosclerosis in Rhesus monkeys
POlHL-1438807 0185 Regulation ol the circulation In
pathological states Rellex control ol venous tone (human.
rabbits, dogs)
POlHL-14388-07 0203 Regulation ol the circulation in
pathological states • Activation ol sympathetic nervous
systems in spontaneously hyperactive rats
POlHL-14388-07 0210 Regulation ol the circulation in
pathological states - EHects ol dietary sodium on blood
pressure and vascular reactivity
POIHL'14388'07 0213 Regulation of the circulation in
pathological states - Regulation ol the heert and peripheral
circulation in heart lailure
P01HL14388-07 0217 Regulation ol the circulation in
pathological states - Fluid mechanics of aortic How (dogs,
human)
POlHL-1438807 0218 Regulation ol the circulation in
pathological states - Regional myocardial dyskinesis-Cause
assessment and reduction (dogs)
POlHL-14388-07 0219 Regulation of the circulation in
pathological states - Myocardial ischemia and infarction in
animals (dogs)
POlHL-14388-07 0221
pathological states
(dogs)
POlHL-14388-07 0222
pathological states
hypertension (rats)
POlHL-14388-07 0233
pathological states
Regulation of the circulation in
Experimental myocardial infarction
Regulation ol the circulation in
Renal perfusion pressure in
Regulation of the circulation in
Pressure-flow relationships after
regression of experimental atherosclerosis
POlHL-144 14-07 0003 Environmental influences on
cardiorespiratory and cellular functions - Exposure to
abnormal gaseous environments (human, dogs, rabbits)
POIHL-14414-07 0015 Environmental influences on
cardiorespiratory and cellular functions - Control of the
cardiovascular system (dogs)
R0IHL-U529-O7 Systems analysis of barorellex (dogs)
ROlHL-14717-06 Hemodynamics and heart structure-
Ventricular overload (dogs)
POlHL-14985-07 0003 Adaptation to hypoxia - Hypoxia
and oxygen transport (human, dogs)
P60HL-15158-07 0025 Comprehensive sickle cell center -
Cardiovascular evaluation ol children with sickle cell
disease (human)
POlHL-15194-07 0017 Pathophysiology ol
cardiopulmonary dysfunction - Coronary circulation and
effects of arteriographic lesions on flow (human)
POlHL-15194-07 0018 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation.
metabolic demand and vasodilatory reserve (human, dogs)
ROlHL-15231-05 Mechanisms of hemodynamic changes
during digestion (dogs)
ROIHL- 15390- 12 Regulation of blood flow in the
microcirculation
ROlHL-15416-06 Cardiovascular control in normal and
disease states (dogs, baboons)
ROlHL-15607-06 Physiological control of splanchnic
circulation (dogs)
ROlHL-15681-06 Coronary flow studies of partially
obstructed vessels (dogs)
ROlHL-15837-06 Renin and cardiac hypertrophy in
hypertension (rats)
ROIHL- 16022-05 Determinants of the ventilatory response
to hypoxia (goats, cats)
R01HL-I6154-05 Membrane lung perfusion for acute
respiratory failure (sheep, baboons)
ROIHI 16206 04 Regresiion ol atheroiclirotlc plaquat
(monkays. dogs)
ROIHL 16233 05 Molecular cardiology ol MOP induced l*lt
ventricular (allure (dogs)
ROIHI 16511 04 Sympathetic allerent activity ol cardiac
origin (dogs, monkeys)
ROIHL 16643 02 Fluorocarbon emulsions as artificial
blood (animals)
ROIHL 16656 06 Lett ventricular function in eiarclst
(dogs)
ROIHL 1675905 Ultrasonic measurement ol cardiac
geometry and How
ROIHL 16938 05 Eltect ol physical lofcei on blood (dogs.
human)
ROIHL 1735504 Pulmonary vascular adjustments in
circulatory collapse (dogs, rats)
ROIHL 1736605 Mechanisms in the production ol renal
hypertension (rabbits, dogs)
ROIHL 17407 05 Peripheral circulation and lluid balance
dish, mammals, human)
ROIHL 17437 03 Perlusion lung-Role ol traumatized
leukocytes (dogs, human)
ROIHL 1745903 Myocardial ischemia (dogs)
ROIHL 1747904 Blood storage- The production ol
cardiotoxic material (dogs, human, swine)
ROIHL 17581 03 Patent ductus arteriosus and pulmonary
hypertension (dogs)
P50HL 17646-04 0001 Study ol ischemic heart disease -
Core clinical investigation unit
P50HL 17646-04 0015 Study of ischemic heart disease -
Protecting ischemic myocardium In patients with evolving
myocardial inlarction
P50HL 17648-04 0034 Study ol ischemic heart disease
Data management-Hemodynamic data
P50HL 17651-04 Ischemic heart disease specialized center
ol research
P50HL-17651-04 0015 Ischemic heart disease specialized
center ol research - Peripheral circulation in acute
myocardial ischemia and infarction (human)
P50HL-1 7651-04 0022 Ischemic heart disease specialized
center of research Electrophysiology -Mechanism and
pharmacology of arrhythmias (human, dog)
P50HL-17651-04 0032 Ischemic heart disease specialized
center of research - Cardiovascular surgery core (human,
dogs)
P50HL-17651-04 0046 Ischemic heart disease specialized
center of research Clinical core-Physiological
changes/biochemical effects ol myocardial ischemia
P50HL-1 7665-04 0001 Study ol ischemic heart disease ■
Reduction ol acute anterior myocardial infarction-
Mechanical circulatory assist
P50HL-17665-04 0002 Study of ischemic heart disease -
Reducing acute anterior myocardial infarction-Beta
adrenergic blockade (human)
P50HL-17665-04 0012 Study of ischemic heart disease -
Myocardial ischemia-Cardiovascular performance in the
conscious baboon and dog
P50HL-17665-04 0022 Study of ischemic heart disease -
Effect of coronary revascularization on left ventricular
function (human)
P50HL-17665-04 0026 Study of ischemic heart disease -
Anesthesia-Myocardial ischemia and hemodynamics in
coronary disease (human)
P50HL-17665-04 0030 Study of ischemic heart disease -
Data management
P50HL-17667-04 0018 Study of ischemic heart disease -
Arrhythmias in ischemic heart disease (human)
P50HL-1766904 0009 Ischemic heart disease center
(SCOR) - Infarct volume-99Tc stannous pyrophosphate
myocardial scintigrams (dogs, human)
P50HL- 176 70-04 0006 Study of ischemic heart disease -
Assessment of coronary artery hemodynamics and
myocardial blood flow (human)
P50HL- 176 70-04 0009 Study of ischemic heart disease ■
Surgical treatment of localized left ventricular dyssynergy
(human, dogs)
P50HL-17670-04 0015 Study of ischemic heart disease
Radionuclide studies of myocardial ischemia (human)
P50HL-1 7682-04 0009 Study of ischemic heart disease -
Computer core unit
P50HL17682-04 0011 Study of ischemic heart disease ■
Nuclear medicine core unit (human, dogs, rabbits, mice)
P50HL-17682-04 0013 Study of ischemic heart disease -
Chronic ischemic heart disease -Myocardial function and
metabolism (dogs, swine)
P50HL- 176 82-04 0014 Study ol ischemic heart disease -
Myocardial ischemia-Instrumentation and technique (dogs,
baboons)
POlHL-17871-04 0010 Kidney, sodium, cardiac output,
arterioles and hypertension - Renal prostaglandins
metabolism in hypertension (rats, dogs)
ROlHL-17931-04 Normalized body surface potential maps
(children)
ROlHL-17974-03 External pneumatic compression in deep
venous thrombosis (human)
ROlHL-17993-04 0003 Ventricular dynamics Irom
surgically inserted markers - Effects of pharmacologic
agents on left ventricular dynamics (human)
ROlHL-17998-04 Regulatory mechanisms in blood
circulation (dogs)
ROIHL- 180 20-04 Splanchnic hemodynamics in man
ROIHI IR024 01 Regional myocardial Mow and tunition
rtlationthipi (dogt)
ROIHL 18050 04 Machanitmt ot cirdiovatcular
teratogeneiii (chick embryo) k embryo)
ROIHL 1809/ 04 Pathogenatis ol acuta itnal failure (rati)
ROIHI 18156 07 Hemodynamics in curved artariei
P50Ht 18318 03 0010 Pathogenetii and complicationi ol
hypertension Hemodynamics in mmeralocorticoid and low
renin hypertension (human)
P50HL 18318 03 0019 Pathogenesis and complicationi ol
hypertension Renin angiotensin system in blood pretturt
regulation (human, rat. dog) ^
P50HL 18323 04 0012 SCOR hypertension centar Renin
as a risk lector (human)
P50HL 18323 04 0042 SCOR hypertension center Blood
viscosity and blood volume in hypertensive disease
(human, dog)
P50HL 18323 04 0046 SCOR hynertension center
Coronary artery h.' .lid hypertcnsicr
(human)
ROIHL 18371 03 Pulmonary hypertension and ventilation
pathophysiology (dogs)
ROIHL 1842604 Regulation ol renal hemodynamics (dogs)
ROIHL 18489-03 Hemodynamic interactions of vasoactive
chemicals (rats)
ROIHL 18492 03 Measurement ol regional coronary How
reserve (human, dogs)
ROIHL 18560-03 Cardiovascular adaptation to stress
(miniature swine)
POIHL 18575-03 0002 Mechanisms of vascular changes
in hypertension Endocrines. electrolytes, and
hemodynamics in hypertension (pigs)
POIHL 1857503 0006 Mechanisms of vascular changes
in hypertension - Evaluation of arterial compliance in
hypertension (human, pigs)
R01HL-I8599-02 Cardiovascular pharmacology of
ionophores (dogs)
POIHL 18646-03 0008 Studies basic to heart
transplantation Immunophysiology and eariy detection of
rejection (dogs)
POlHL-18646-03 0010 Studies basic to heart
transplantation - Development and study of a heart
preservation chamber (dogs, sheep)
ROlHL-1865703 Pharmacologic studies on neurogenic
digitalis eflects (human, cats, dogs)
POlHL-18708-03 0010 Oxygen, energy and contractility in
cardiac tissue - Tissue oxygen utilization (rats, dogs)
R01HL18731-02 RES stimulating materials in
experimental shock (dogs)
ROlHL-18749-03
heart (dogs)
ROlHL-18769-04
(human)
ROIHL 18848-03
heart disease (dogs, cats)
Ventricular mechanics in the overloaded
Studies in survivors of lethal arrhythmias
Etiology and development of congenital
Intercellular factors in function of
Pulseless How and circulatory assistance
*Eicliides routine methodok>gy OR covers only general projects which preclude indexing at the specific level.
**(Mented significanthf to above subject.
ROIHL- 18900-03
cardiac cells
ROIHL- 18948-03
(dogs, calves)
ROlHL-18977-03 Non-invasive diagnosis ol peripheral
arterial disease (human, dogs)
ROlHL-18995-04 Cardiovascular determinants ol
catecholamine release (dogs)
ROlHL-19039-03 Circulation studies by one vs two circuit
model (dogs)
ROIHL 19044-03 Effect of drugs on development of
cardiac failure (cats)
ROlHL-19057-03 Catecholamines and cyclic AMP in
cardiovascular system (rats, dogs)
ROIHL- 19066-03 Synthesis and evaluation of
prostaglandin metabolites (guinea pigs)
ROlHL-19139-03 Dispersion of diffusible indicators in the
body (human, cats, dogs)
ROlHL-19144-03 Contraceptive steroids and experimental
hypertension (rats)
ROlHL-19225-02 0003 Types and mechanims of
pulmonary hypertension - Cardiopulmonary function in pigs
and rats
ROlHL-19257-03 Cardiovascular adjustment to behavioral
stress (dog)
ROlHL-19287-03 The antihypertensive function of the
renal medulla (human, rats, rabbits)
ROlHL-19298-03 Pulmonary hemodynamics (dogs, cats)
ROlHL-19343-03 Behavioral influences on cardiac
contractility (monkeys)
ROlHL-19366-03 Renal Starting forces in experimental
conditions (rats, rabbits)
R01HL19370-03 Coronary capillary exchange-The effects
pf ischemia (dogs, sheep)
ROlHL-19391-03 Dynamic determinants of left ventricular
filling (dogs)
ROIHL 19406-03 Grading of atherosclerosis by CW doppler
ultrasound (human, dogs)
ROlHL-19461-03 Myocardial energetics in hypertrophy and
heart failure (rabbits)
ROlHL-19463 02 Pathophysiology of acute renal failure
(rats)
ROlHL-1983002 Shear to aortic histamine synthesis and
permeability (dogs)
ROlHL-19977-02 Genesis of circulatory shock by
pancreatic peptides (cats, dogs)
(contd)
M Grant has subprojeds describing specific research aspects.
See Appendix lor investigator's name and grant number.
CAR
ROlHL-20143-02 Hypothermic circulatory arrest -Cerebral
vascular change (dogs)
ROlHL-20163-02 Competitive coronary flow in native and
graft vessels (dog)
ROlHL-20226-02 Cardiac bypass and coronary collateral
physiology (dogs)
ROlHL-20283-02 Maintenance of cellular integrity in
ischemic hearts (cats)
ROlHL-2035602 Development and evaluation of an
artificial heart (calves)
ROlHL-20371-02 Intravascular redistribution of blood
volume (dogs)
ROlHL-20542-03 Regional hemodynamics in spontaneous
hypertension (rats)
POlHL-20552-02 0002 The development and regression of
cardiac hypertrophy - Effect of treatment on the
hypertrophied left ventricle (rats)
ROlHL-20572-02 Hemodynamic relations to metabolism in
hypertension
ROlHL-20572-02 0001 Hemodynamic relations to
metabolism in hypertension - Hemodynamic and myocardial
functional studies in the SHR (rat)
' ROlHL-20572-02 0003 Hemodynamic relations to
metabolism in hypertension ■ Cardiac output and organ
blood flow in hypertension (rats)
' ROlHL-20572-02 0008 Hemodynamic relations to
metabolism in hypertension - Role of nervous system in
hemodynamic function
ROlHL-20610-02 Nerve growth factor and obstructive
cardiomyopathy (dogs)
> ROlHL-20690-02 Pulmonary hemodynamics in lung edema
during PEEP (dogs)
' ROlHL-20766-02 Control of circulation in heat stress
(baboons)
ROlHL-2080302
lambs, cats)
* ROlHL-20829-02 Fluid mechanics of heart valve
prostheses (dogs, human)
ROlHL-20835 02 Signal analysis of turbulence study in
blood
ROlHL-20861-01
(dogs)
ROlHL-20979-02
ROlHL-21034-01
occlusion (dogs)
ROlHL-21071-02
Intraaortic balloon pumping (dogs,
Cardio-respiratoryrenal stress reactions
A novel pulsed Doppler flowmeter (dogs)
Compensatory responses to arterial
Mechanisms of hypertension in
coarctation of the aorta (dog)
R23HL-2115102 Ischemic myocardium-Delivery of blood
flow and drugs (dogs)
R23HL-21168-01 Hypoxemic respiratory failure -Physiologic
evaluation (human, dogs)
R23HL-2 1203-02 Effect of vasoactive agents on left-to-
right shunts (lambs)
R23HL-2I234-D2 The regulation of cardiac hypertrophy
(rabbits)
ROlHL-21257-02 Breathing in sleep -Airway control and
blood gases (cats)
ROlHL-21270-01 Correlation of arterial hemodynamics and
morphology (human)
ROlHL-21293-02 Randomized study of coronary bypass
surgery (human)
R23HL-21298-02 Coronary vasomotion (dogs, pigs)
ROlHL-21438-02 Structure and permeability of arterial
endothelium (pigs)
ROlHL-21452-02 Pulmonary capillary filtration in
myocardial ishemia (dogs)
ROlHL-21523-01 Hemodynamic effects of dietary sodium
in man
ROlHL-21572-01
syndrome
ROlHL-21589-01
ischemic heart
ROlHL-21657-01
hypoxia (dogs)
ROlHL-21796-01
vascular surgery (dogs)
ROlHL-21817-01
circulation
ROIHL 21893-01
(human)
R23HL-21943-01
edema (dogs)
R01HL-21985-0I
disease
ROIHL 2203201
(human)
ROIHL 22069-02
(dogs)
ROIHL 221 13-02
foot lesions (human)
POIHL 22163-01 0003 Surface thrombogenesis -
Mechanisms and prevention - In vivo mechanisms of
biomaterial thrombogenesis and its prevention (baboons)
ROlHL-221 72-01 Hypotension, renal ischemia and effect of
mannitol (dogs, rats)
ROlHL-22223-01 The cardiopulmonary junction (dogs,
models)
ROIHL 22326-01
output (dogs)
ROIHL 22455^)1
Natural history of the postphlebitic
Radiographic contrast toxicity in
Regional non-ischemic myocardial
Applied pulsatile hemodynamics in
(dogs)
Catecholamines, blood pressure and
Blood volume distribution in hypertension
Capillary morphology in pulmonary
Videoroentgenography in congenital heart
Cardiovascular events in hyperteiisives
Experimental renal arterial hypertension
Micro/macrovasculature in healing of
Noninvasive measurement of cardiac
ROlHL-22482-01
excretion (dogs)
ROlHL-22506-01
hypertensions
ROlHL-22561-01
circulation (cats)
ROlHL-22641-01
112
Circulatory hemodynamics and sodium
Hemodynamics of the clinical
Hormonal control of mesenteric
Platelet concentration in the marginal
layer (dogs, human)
Ventilation, perfusion, and systemic
arterial reflexes (dogs)
ROlHL-22661-01 Chronic total cardiopulhonary mechanical
substitution (sheep)
** R23HL-22747-01 Cardiodynamics and hypertension under
cerebellar control (dogs)
R01HL-22759-01 Regional myocardial blood flow during
hypothermia (dogs)
** R01HL-22783-01 Hemodynamic induction of intimal
fibromuscular lesion
** R01HL-22928-01 Systematic study of bronchial circulation
(sheep)
*• R23HL-22975-01 Dynamics of autoregulation of muscle
blood flow (dogs)
** R01HL-22977-01 Role of vasoconstrictor mechanisms in
heart failure (human, dogs)
ROlHL-23201-01 Mechanisms of hypertension (human,
rats)
** ROlHL-233 12-01 Hemodynamics and vasoactivity in renal
hypertension (human, dogs)
ROlHL-23970-01 Mechanisms and control of sudden
cardiac death (human, dog)
NOlHR-62920-02 Noninvasive diagnosis of pulmonary
hypertension (dog, human)
NOlHV-42914-13 Solenoid left ventricular assist system
(cattle)
NO lHV-629 60-00 Techniques to protect ischemic
myocardium and minimize infant size (human)
NOlHV-72936-00 Left heart assist device development
(human, cattle)
NOlHV-72939-01 Develop and evaluate left heart assist
blood pumps (human, calves, pigs)
CARDIOVASCULAR FUNCTION, BLOOD
CIRCULATION TIME
ROlHL-225 12-01 Ultrasonic instrumentation for
cardiovascular studies
CARDIOVASCULAR FUNCTION, BLOOD FLOW
SEE ALSO BLOOD STASIS
SEE ALSO CARDIOVASCUUR DISORDERS DIAGNOSIS, BLOOD
FLOW MEASUREMENTS*
SEE ALSO CARDIOVASCULAR DISORDERS DIAGNOSIS, BLOOD
PRESSURE GRADIENT TECHNIQUE*
SEE ALSO CARDIOVASCULAR DISORDERS DIAGNOSIS,
PLETHYSMOGRAPHY*
** N01HI-02216-10 To develop biological flow NMR concept
(human, mammals non human)
ROlHL-00487-29 Vasomotor tone and venous return
(human, dogs, monkeys )
ROlHL-02493-22 Kidney function in experimental heart
failure (dogs, rats)
** ROlHL-03181-21 0020 Hemodynamics as applied to
surgical problems - Blood flow measurement-Cardiac
output and regional flows (dogs)
** ROlHL-03181-21 0025 Hemodynamics as applied to
surgical problems - Vascular stenosis (dogs)
** ROlHL-03181-21 0027 Hemodynamics as applied to
surgical problems - Hemodynamic studies of the Gl tract
(dogs)
ROlHL-03290-22 Controls of cardiac and vascular smooth
muscles (cats, rats, dogs)
** ROlHL-03941-18 Uterine blood flow and changes in
pregnancy (sheep)
POlHL-04664-18 0001 Cardiovascular and lung dynamics
- X-ray projection image videodensitometry (dogs)
ROlHL-05875-18 Pathologic metabolic and physiologic
studies of heart (human, dogs, cats)
** ROlHL-05883-18 0007 Reflex control of resistance and
capacitance vessels - Prostaglandins and skeletal muscle
blood flow (dogs)
ROlHL-06143-18 Response of the totally denervated heart
to exercise (dogs)
** POlHL-06285-18 0131 Cardiovascular-respiratory
physiology and biochemistry - Fetal heart development and
ventricular outflow obstruction (lambs)
POlHL-06285-18 0133 Cardiovascular-respiratory
physiology and biochemistry - Decreased uterine blood flow
and fetal development (lambs)
POlHL-06285-18 0135 Cardiovascular-respiratory
physiology and biochemistry - Beta-adrenergic agents and
fetal cardiovascular dynamics (lambs)
POlHL-06285-18 0143 Cardiovascular-respiratory
physiology and biochemistry - Myocardial ischemia (human,
dogs, lambs)
** POlHL-06285-18 0147 Cardiovascular-respiratory
physiology and biochemistry - Metabolic regulation of
cerebral microcirculation (cats)
POlHL-06285-18 0157 Cardiovascular-respiratory
physiology and biochemistry - Left ventricle outflow
impedance analysis (human)
POlHL-06296-18 0002 Cardiovascular and pulmonary
adaptation to stress ■ Respiratory muscle blood flow,
mechanics and metabolism (human, dog)
POlHL-06296-18 0005 Cardiovascular and pulmonary
adaptation to stress - Regulation of ventricular
performance (animals)
CAR
POlHL-06312-17 0028 Surgical cardiology - Coronary flow
in the transplanted denervated heart (dogs)
POlHL-06312-17 0049 Surgical cardiology - Long-term
pulmonary vascular resistance (human)
ROlHL-06736-18 Biogenic-mechanical factors in
microcirculation (rats, gerbils)
POlHL-07293-17 0051 Non-invasive cardiovascular
measurements - Physiologic evaluation of duplex scanner
(dogs)
POlHL-07293-17 0055 Non-invasive cardiovascular
measurements - Peripheral vascular transducer position
locating system
ROlHL-08311-14 Effects of drugs upon myocardial hypoxia
(dogs, turtles)
ROlHL-08570-15 Pharmacologic and reflex influence on
vascular tone (dogs, rabbits)
' ROlHL-08977 14 Quantitation of flow and solute flux in
microvessels (cats, rats)
' ROlHL-09154-14 Central control of distribution of organ
blood flow (monkeys)
' ROlHL-09711-13 Instantaneous blood flow in ascending
aorta (human, dogs)
ROlHL-10182-13 Circulatory function and electrolytic
metabolism (dogs, human)
' ROlHL-10330-11 Physiological mechanics of the heart and
arteries (dogs, rabbits, horses)
POlHL-1034213 The integrated function of respiration
and circulation
' ROlHL-10384-13 Blood flow and nucleotide metabolism
(animals)
POIHL- 10436- 13 0006 A multidisciplinary study of
congenital heart disease - Ventricular blood pumps and
valves (human, cattle)
ROlHL-10612-13 0018 Humoral factors in heart failure
and hypertension The pathogenesis of experimental renal
hypertension (dogs, rabbits, rats)
* ROlHL-11152-12 Vascular physiology (human, cats, dogs)
* ROlHL-11153 12 Quantitation of flow and solute flux in
microvessels (cats, rats)
* ROlHL-1 1289-12 Analysis of stress in pulsatile dynamics
I POIHL 11351-12 Cellular and molecular mechanisms of
myocardial function
POlHL-11678-11 0063 Cardiovascular dynamics and their
control - Renin-angiotensin system -Control of renal
hemodynamics, electrolyte excretion
* ROlHL-11717-09 Effect of stenotic obstructions on flow in
arteries (dogs)
ROlHL-11906-11 Comparative study of heart function
(cats. rats, hedgehogs, squirrels)
ROlHL-11945-10 Synthesis of artificial lung and kidney
systems (sheep, mice, swine)
* R01HL-12083-11 Flow field in aorta and its major
branches (dogs, phantom models)
ROlHL-12415-10 Evaluation of left ventricular function
(dogs, rabbits)
'* ROlHL-12494-10 Continuum mechanics in biophysics
(human, animals)
'* POlHL-12738-10 0111 Physiologic pharmacology and its
clinical applications - Cardiovascular pharmacology (dogs)
ROlHL-12792-09
(hamsters, rats)
Local control of the microcirculation
Regulation of sodium excretion (dogs.
ROlHL-12827-08
rats)
R01HL-12839-09 Flow, transport and membrane
phenomena in blood (human)
ROlHL-12974-10 Tracer kinetics, flows and masses in
body organs (human, dogs)
ROlHL-13134-07 Mechanism of chemoreceptor discharge
(cats)
POlHL-13330-08 0059 Mechanical circulatory support -
Physiologic evaluation of circulatory assistance (cattle)
ROlHL-13437-09 Physical and mechanical parameters in
the microcirculation (animals)
ROlHL-13454-08 Behavioral stress and cardiomyopathy
(monkeys, cats)
ROlHL-13654-08 Antilipemic regimes in peripheral
arteriosclerosis (human)
P01HL-13737-07 0013 Assisted circulation - Incorporation
of sensors (human, dogs)
' POlHL-13737-07 0034 Assisted circulation - Phasic aortic
flow and cardiac output from phasic pressures (dogs)
POlHL-13738-08 0002 Cardiac assist devices and
artificial hearts - Total replacement with artificial heart
(calves, sheep, ponies)
POlHL-13851-16 Cyclotron produced isotopes in biology
and medicine (human, animals)
ROlHL-13929-06 Single nephron response to chronic
obstruction (frogs, rats)
ROlHL-13936-06 Microvascular responses in hypertension
(human, rats)
P50HL-14138-05 0009 Center for research on
atherosclerosis - Core angiographic-diagnostic laboratory
(human, dogs, birds)
ROlHL-14148-07 The regional circulations
ROlHL-14148-07 0009 The regional circulations -
Myocardial circulation in hypertension and atherosclerosis
(human)
P50HL-14164-07 0038 A/S SCOR-Comparative and
experimental atherosclerosis - Peripheral vascular studies-
Cholesterol, lesion regression, vascular function
(contd)
•Excludes routine methodokigy OR covers only general prajects which preclude indexing at the specific level.
"Onented significantly to above subject.
M Grant has subproiects describing specific research aspects.
See Appendix for investigators name and grant number.
CAR
1 13
PiOHt 14187 0' OOIS Pulmonatv SCOR Chamlcal
mtdialois in pulmonarY vasciilii ic^ponsts
Pathuphysioloiic rasponsts ol pulmonatv capillaiy bad
(dog. human)
PSOHL 14214 O; 0026 Newborn lung cvntei lot hyalma
mambtana disaasa Hamodynaniic studies ol HMD
Pioslaglandlns production and blockais (lamt)s)
PbOHL 14214 o; 0029 Nawboin lung center lor hyaline
membrana disease The diving retiei Perinatal asphyiia,
pulmonary ischemia and HMD (sheep)
PSOHL 14230 07 0094 VS SCOR Lipids, atherosclerosis
and thrombosis Studies ol atherosclerosis and regression
(monkeys)
PSOHl 14236 0b 0002 Prevention ol premature
arteriosclerosis Myocardial blood How in patients with
coronary artherosclerosis
P50HL 14236 0!) 0007 Prevention ol premature
arteriosclerosis Exercise stress testing
hyperlipoproteinemia (human)
POIHI 1438807 0157 Regulation of the circulation in
pathological states Autoregulation ol renal blood How and
distribution in sodium excretion control
POIHL 1438807 0161 Regulation ol the circulation in
pathological states Heterogeneity ol lelt ventricular
perlusion in awake dogs
POIHL 14388C7 0162 Regulation ol the circulation in
pathological states Phasic coronary How and myocardial
perlusion in aortic regurgitation (dogs)
POIHL 1438807 0179 Regulation ol the circulation in
pathological states Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
POIHL 14388 07 0180 Regulation ol the circulation in
pathological states Regulation ol cerebral blood How
(dogs, monkeys)
POlHL-1438807 0185
pathological states
rabbits, dogs)
P01HL-U388-07 0197
pathological states
Surgery and non obsliuitivo
(xercise itnd %upp(y demand
Regulation ol the circulation in
Rellex control ol venous tone (human.
Regulation of the circulation in
Pharmacology ol the coronary
Regulation ol the circulation in
Experimental myocardial infarction
Regulation of the circulation in
Altered vascular reactivity in
pathogenesis of spontaneous hypertension (rats)
POlHL-14388-07 0210 Regulation of the circulation in
pathological states - Effects of dietary sodium on blood
pressure and vascular reactivity
■ POIHL 14388 07 0217 Regulation of the circulation in
pathological states - Fluid mechanics of aortic flow (dogs.
human)
POlHL-14388-07 0220
pathological states ■
circulation in man
' POIHL 14388-07 0221
pathological states -
(dogs)
POlHL-14388-07 0225 Regulation of the circulation in
pathological states ■ Release of renal prostaglandins by
saluretic-diuretic agents (dogs)
POlHL-14388-07 0231 Regulation of the circulation in
pathological states - Mechansim of cutaneous
vasodilatation in Paget's disease of bone
POlHL-14388-07 0233 Regulation of the circulation in
pathological states - Pressure-flow relationships after
regression of experimental atherosclerosis
P01HL-14414-07 0008 Environmental inHuenccs on
cardiorespiratory and cellular functions - Energetics of
swimming (human)
POlHL-14414-07 0015 Environmental influences on
cardiorespiratory and cellular functions ■ Control of the
cardiovascular system (dogs)
ROlHL-14644-05 Optimization diastolic augmentation and
systolic sink (dogs)
ROlHL-14645-07 Blood flow measurement by ultrasonic
catheter tip methods (human, dogs)
ROlHL-14914-06 Autoregulation of glomerular filtration
rate (rats)
POlHL-15194-07 0001 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation, venous
drainage and collateral How (human, dogs)
ROlHL-1 5270-06 Local mechanical properties of the aortic
tissue (dogs, pigs)
ROlHL-1 5390-12 Regulation of blood flow in the
microcirculation
ROlHL-15392-06 Autonomic and circulatory actions of
anesthetics (dog. cat. rabbit, monkey)
ROlHL-15430-05 Cardiopulmonary adaptation of newborns
to altitude (human)
ROIHLI 5447-06 Vascular role of prostaglandin and cyclic
nucleotides (rats)
ROlHL-15562-05 Regulation of skeletal muscle blood flow
(dogs)
ROIHL- 15580-06 Humoral control of pulmonary and
systemic circulation (animals)
R01HL1565505 Blood flow and gas exchange in placenta
and lungs (sheep) rabbits)
ROlHL-1572206 Hemorrheology studies related to in vivo
blood flow (human)
ROlHL-15839-05 Physiological role of isorenin and
kallikrein (animals)
ROlHL-16066-05 Studies on neurogenic control of the
circulation (human, dogs)
ROIHL- 16094-06 The dynamics of microcirculatory function
(dogs)
R01HL1623604 Detailed characteristics of coronary blood
flow (horses, dogs, calves)
ROIHl 16292 05 0009
coronary insulliciency
biilancii (human)
KOIlll 16.U5 05 Analysis ol Interaction between CMS
viisumolor systems (cats, rats)
PUIIU 1638/04 0005 The blood vessel and
thrombogenesis Fluid engineering considerations in
Ihromhogenosis
ROIHI 16412 04 Release ol nucleosides Irom the ischemic
heart (human, dogs)
ROIHL 16580 04 Mathematical models lor studying sickle
cell disease
ROIHL 16582 05
ROIHL 16648 16
activity (cats)
ROIHL 1675905
geometry and How
POIHL 16833-04 Hemoglobin and red cell system in
hemoglobinopathies
POIHL 16851 04 Human red cell membrane in health and
disease
Human red cell membrane in
force balance in red cell interactions
Artilicial lungs (dogs)
Integrated control of cardiovascular
Ultrasonic measurement ol cardiac
POIHL 16851 04 0008
health and disease
(human)
POIHL 16851 04 0009
health and disease
Human red cell membrane in
Blood cell properties in circulatory
regulation (dogs, rabbits)
POIHL 1691005 Regulation ol the peripheral circulation
POIHL 1691005 0001 Regulation ol the peripheral
circulation Quantitative studies ol microcirculatory control
(bats)
' POIHL 16910-05 0005 Regulation of the peripheral
circulation Control ol circulation by baroreceptor and
chemoreceptor reflexes (dog. monkey)
' POlHL-16910-05 0006 Regulation of the peripheral
circulation - Regulation of blood flow distribution (baboons,
dogs)
' POIHL 16910-05 0007 Regulation of the peripheral
circulation - CNS -Behavioral influences on circulation
(baboons)
■ POIHL-16910-05 0008 Regulation of the peripheral
circulation - Circulation to bone (dogs, baboons)
■ P60HL- 172 6904 0023 National heart and blood vessel
research and demonstration center Cardiovascular
pharmacology -Ischemia, shock and heart failure (dog. cat.
rat)
P60HL 17269-04 0024 National heart and blood vessel
research and demonstration center - Section of
experimental cardiovascular surgery-Core facility
P60HL-17269-04 0032 National heart and blood vessel
research and demonstration center - Clinical circulatory
assist device labncation
ROlHL-17403-03 Metabolic control of cardiac output
(dogs)
ROlHL-1740803 Fresh blood rheology-Relation to
cardiovascular risk (human)
POlHL-17421-05 0002 Regulation and exchange in the
microcirculation - Metabolic and myogenic blood flow
regulation in microcirculation (animals)
POlHL-17421-05 0004 Regulation and exchange in the
microcirculation - Localization of flow regulation in the
microcirculation (cats, human)
POIHLI 7430-05 0007 Control of coagulation - Platelet
adhesion, aggregation, ultrastructure in flowing blood
(human, animals)
ROlHL-17591-03 Development ol electromagnetic
rheoangiography (human, dogs)
ROIHL-17628-03 Pulsatile pressure-flow dynamics (dogs)
P50HL-17646-04 0014 Study of ischemic heart disease -
Progression of ischemic injury in conscious dogs (also
rabbits)
P50HL-1 7648-04 0004 Study of ischemic heart disease -
Radionuclide imaging studies (human, pig)
P50HL1 7648-04 0006 Study of ischemic heart disease ■
Ventricular perTormance and myocardial perfusion in
obstructive coronary disease
P50HL 17648-04 0011 Study of ischemic heart disease ■
Surgical treatment for acute myocardial ischemia (human,
dogs)
P50HL-1 7648-04 0013 Study of ischemic heart disease -
Fate of bypassed and bypassing vessels (dogs)
P50HL-1764804 0021 Study of ischemic heart disease -
Biventricular contractile responses to acute myocardial
infarction (mammals)
P50HL17648-04 0023 Study of ischemic heart disease -
Chemical mediators of inflammation in acute myocardial
infarction (mammals)
P50HL-17651-04 0002 Ischemic heart disease specialized
center of research - Reduction of myocardial ishemic injury
by pharmacologic agents (human, dog)
P50HL-17651-04 0016 Ischemic heart disease specialized
center of research ■ Retroperfusion of coronary venus
circulation with therapeutic agents (dogs)
P50HL-1765I-04 0037 Ischemic heart disease specialized
center of research - Measurement of coronary venous
outflow by thermodilution (human)
P50HL-17651-04 0039 Ischemic heart disease specialized
center of research - Measurement and prediction of infarct
size (human, dog)
P50HL-17651-04 0043 Ischemic heart disease specialized
center of research ■ Gradual reperfusion following acute
coronary occlusion (dog)
CAR
P50HI 1/651 04 0044 Itchenii: haart diuau >p«ciali/«d
center of research limb blood How tHer myocardial
levsMulori/ation (human)
P50HI 1 765 1 04 0045 Itchtmic heart dlteate ipacialind
center ol mwHfc.u Peripheral vascular ituditi
Pharmacology (dogs, human)
P50HI 1/655 04 0001 Study ol iichemic heirl ditti«t
Intravenou'. nitroglycerin Ventricular function and inlarcl
M/e (human, dog)
' P50HI 1 /655 04 0001 Study ol ischemic heart dlieaia
Cardiopulmonary resuscitation (human, dog)
P50HI 1 /655 04 0006 Study ol ischemic heart dluiM
Evaluation ol coronary artery bypass gralt surgery (human)
P50HI 1/655 04 0014 Study ol ischemic heart diseate
Blood How and gas tension in myocardial ischemia and
infarction (dog, monkey)
P50HL 1/665 04 0021 Study ol ischemic heart disease
Identilication, prevention Myocardial ischemia in
cardiopulmonary bypass (dog)
P50HL 1/665 04 002 7 Study ol ischemic heart disease
Positron imaging of regional myocardial perfusion (human,
dog)
P50HL 1/669 04 0012 Ischemic heart disease center
(SCOR) Circulatory assistance (human, dog)
P50HL 1/6/0-04 0006 Study ol ischemic heart disease
Assessment ol coronary artery hemodynamics and
myocardial blood How (human)
P50HL 176/0 04 0011 Study ol ischemic heart disease
Pharmacology ol ischemic myocardium (dogs)
P50HL 17670 04 0021 Study ol ischemic heart disease
Enzymatic evaluation ol acute myocardial inlarction (dogs)
P50HL-I7682 04 0005 Study of ischemic heart disease
Regional myocardial perfusion deficits and segmental
contraction disorders in man
P50HL 17682 04 000/ Study of ischemic heart disease -
Mechanisms of hypoxemia in myocardial infarction (human)
P50HL 17682-04 0011 Study of ischemic heart disease -
Nuclear medicine core unit (human, dogs, rabbits, mice)
P50HL- 17682-04 0014 Study ol ischemic heart disease -
Myocardial ischemia -Instrumentation and technique (dogs.
baboons)
P50HL-17682 04 0015 Study of ischemic heart disease -
Acute myocardial ischemia and infarction and their
reversibility (dogs, baboons)
P50HL-17682-04 0016 Study of ischemic heart disease •
Endurance exercise -Prevention and rehabilitation in
ischemic heart disease (pig)
P50HL-17682-04 0020 Study of ischemic heart disease -
Nucleotide and nucleoside metabolism in ischemic
myocardium
P01HL17731-04 0001 Physiological basis of pulmonary
disease - Mechanisms of blood flow and ventilation (dogs)
ROlHL-17732-03 Peripheral venomotor control in thermal
stress (human)
ROlHL-17739-04 Acute myocardial infarct scintigraphy
(human, dogs, rats)
ROlHL-17759-03 Studies of myocardial reactive hyperemia
(dogs, human)
ROlHL-17808-03 Effect of altered oxygen afflnity on
oxygen transport (human, rats)
ROIHL- 17809-04 Effects of exercise on the coronary
vasculature (rat. dog)
ROlHL-17853-03 Peripheral circulation in heart failure
(animals)
ROlHL-17859-04 Computational methods in cardiac fluid
dynamics
POlHL-17871-04 0009 Kidney, sodium, cardiac output.
arterioles and hypertension Kidney, sodium, cardiac
output, arterioles and hypertension
ROlHL-17903-03 Regional circulatory responses to hypoxia
(rats. cats, rabbits)
ROlHL-17932-04 Blood flow regulation in muscle (cats)
ROlHL-17954-03 Narcotics and the circulation (human.
dogs, pigs, monkeys)
R01HL-I7969-04
valves (dogs)
ROIHL- 1799804
circulation (dogs)
ROlHL-1809604
(primates, dogs)
ROlHL-18097-04
ROlHL-18145-03
Function and structure of semilunar
Regulatory mechanisms in blood
Vasoactive agents In splanchnic viscera
•Excludes nxitine melhodok>gy OR covers only general projects which preclude indexing
**Oiiented significanthi to above subject.
at the specific level.
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
Pathogenesis of acute renal failure (rats)
Oxygen transport mechanisms in hypoxia
(dogs. rats, rabbits)
POlHL-18208-04 Center for the study of blood cell
rheology
POlHL-18208-04 0004 Center for the study of blood cell
rheology - Splenic microcirculation (rats, mice)
POIHL 18208-04 0006 Center for the study of blood cell
rheology - Analysis of flow in arterioles and capillaries
(human)
ROlHL-18292-04 Vasodilation and microvascular oxygen
delivery (dog. hamster)
P50HL-183 18-03 0007 Pathogenesis and complications of
hypertension - Humoral factors and renal function in
experimental hypertension (rats)
P50HL-1831803 0013 Pathogenesis and complications of
hypertension - Humoral factors and renal function in
human hypertension
ROlHL-18321-03 Fluid shear or magnetic alignment of
blood components (human)
P50HL-18323-04 0012 SCOR hypertension center - Renin
as a risk factor (human)
(contd)
CAR
Circulation studies by one «s two circuit
Hypoxia-induced relaxation of vascular
Sustained increase in cardiac output
ROlHL-18467-03 Fingertip blood flow in normals and
Raynaud's disease (human)
ROlHL-18468-03 The distribution of flow in the
myocardium (dog, pig)
ROltfL-18489-03 Hemodynamic interactions of vasoactive
chemicals (rats)
ROlHL-18599-02 Cardiovascular pharmacology of
ionophores (dogs)
ROlHL-18644-03 Prosthesis for aortocoronary bypass
(dogs, baboons)
ROlHL-18718-04 Prostaglandin precursors and vascular
reactivity (dogs)
R01HL1880S-04 0005 Sudden cardiac death and the
onset of myocardial infarction - Sudden death survivors -
Radionuclide studies (human)
ROlHL-18845-04 Regulation of renal circulation and salt
excretion (rats, dogs)
ROlHL-18868-03 Development of vertebrate vascular
control systems (reptiles, amphibians)
R01HL18948-03 Pulseless flow and circulatory assistance
(dogs, calves)
ROlHL-18969-02 Arterial wall oxygenation (rabbits, dogs)
ROlHL-18976-03 Blood pressure control-Relation to
behavioral stress (human, dog)
' R01HL'1899S-04 Cardiovascular determinants of
catecholamine release (dogs)
ROlHL-19003-03 High precision densitometry of coronary
angiograms
R01HL19038-02 Plethysmographic evaluation of carotid
blood flow (human, rabbits, dogs)
R01HL19039-03
model (dogs)
ROlHL-1908201
smooth muscle
ROlHL-19091-02
(dogs)
ROlHL-19173-03 Analysis of blood trauma from
microporous oxygenators (human, dogs, rabbits)
R01HL19182-03 Surgical aspects of myocardial
hypertrophy (dogs)
P50HL-19190-02 0006 Pulmonary SCOR-Pathophysiology,
management of IRDS - Asphyxia-Respiratory control (dogs)
* POlHL-19242-02 0003 Study of vascular smooth muscle -
Vasoactive metabolites from vascular muscle and
parenchymal tissue (animal)
POlHL-19242-02 0006 Study of vascular smooth muscle -
The contractile system of vascular smooth muscle (swine,
rats)
* ROlHL-19256-03 Arterial baroreceptors in cardiovascular
control (dogs)
ROlHL-19350-02 Prevention of thrombosis by applied
electric fields (sheep)
ROlHL-1941403 Protection of myocardium during cardiac
surgery (dogs, cats, human)
ROlHL-19454-02 Rheological factors in transport across
arterial wall (dogs)
ROIHL- 19463-02 Pathophysiology of acute renal failure
(rats)
ROlHL-19675-02 Coronary pharmacoangiography
ROlHL-19677-03 Venous structure and function (dogs)
POlHL-1973702 0006 Cellular and molecular aspects of
respiratory physiology - Tissue oxygenation and
mitochondrial respiratory activity (sheep)
P01HLI9737-02 0007 Cellular and molecular aspects of
respiratory physiology - Average oxygen tension of tissue
using radioisotopes (dogs)
P01HL19737-02 0009 Cellular and molecular aspects of
respiratory physiology • Regulation of tissue oxygen tension
and body carbon monoxide stores (human, dogs)
* POlHL-19737-02 0010 Cellular and molecular aspects of
respiratory physiology - Effects of pulsatile flow and volume
on capillary exchanges (dogs, rats)
ROlHL'19824-02 Mass transfer in the microcirculation
'* ROlHL-2017702 Effects of erythrocyte deformability on
tissue perfusion (rats)
ROlHL-20253-02 Effects of exercise on the heart and its
blood supply (dogs)
•* ROlHL-20399-03 Vascular control in experimental diabetes
mellitus (dog)
ROlHL-20401-03 Relationship of insulin to catechol
cardiomyopathy (rabbit, pig)
ROlHL-20428-03 The juvenile diabetic heart (human)
R01HL-20S17-03 Diabetes, somatotropin, factor VIII and
atherosclerosis (human, animal)
•* ROlHL'20572-02 0003 Hemodynamic relations to
metabolism in hypertension - Cardiac output and organ
blood flow in hypertension (rats)
ROlHL-20605-02 Microvascular responses during intestinal
absorption (rats)
ROlHL-20630-03 Development of a pulsed Doppler velocity
detector (human, animals)
ROlHL-20634-01 Blood volume and venous return In
thermal strain (human)
•• ROlHL-20674-02 Evaluation of cardiac function with
radioactive tracers
•* ROlHL-20685-02 Pituitary-adrenergicovarian vasomotor
interaction (dogs)
ROlHL-20720-02 Myocardial protection during
cardiopulmonary bypass (dogs)
ROlHL-20869-01 Microvascular responses to ultrasound
ROlHL-20979-02 A novel pulsed Doppler flowmeter (dogs)
114
POlHL-21016-02 0013 Sickle cell anemia and other
hemoglobinopathies - Microcirculatory response to sickle
cell treated with anti-sickling agents (rats)
R23HL-21151-02 Ischemic myocardium-Delivery of blood
flow and drugs (dogs)
ROlHL-21308-01 Prostaglandins and local control of the
circulation (rats, dogs)
R23HL-21332 02 Pulsatile regulation of flow in the
microcirculation (cats)
R23HL-21434-02 Intrinsic control of coronary blood flow by
chemicals (guinea pigs)
ROlHL-21451-01 Control of circulation during heat stress
and fever (baboon)
ROlHL-21500-02 Performance of respiratory muscles under
stress (dogs)
R23HL-21559-01 Oxygen supply and blood flow through
aortic vasa vasorum (dogs)
ROlHL-21751-02 0002 Thallium and antimyosin in
ischemia and infarction - Canine models of ischemia and
infarction
ROlHL-21859-01 Unsteady flow in arterial bifurcations
(human)
R23HL-21914-01
' ROlHL-221 18-02
mellitus
ROlHL-221 54-01
(dog)
POlHL-22163-01 0001 Surface thrombogenesis-
Mechanisms and prevention - Initial blood protein and
platelet interactions with biomaterials (baboons)
POlHL-22163-01 0002 Surface thrombogenesis-
Mechanisms and prevention - Laser-scattering detection of
microemboli in blood flow (baboons)
' ROlHL-22225-01 Hormonal regulation of blood pressure
and blood flow (human, animals)
ROlHL-225 12-01 Ultrasonic instrumentation for
cardiovascular studies
ROlHL-22561-01 Hormonal control of mesenteric
circulation (cats)
ROlHL-22573-01 Treatment of post surgical
vasoconstriction (dogs, monkeys, human, rats)
R23HL-22575-01 Factors modifying cardiac digoxin effects
and content (dogs, cats)
* ROlHL-22583-02 Ultrastructural study of endothelium in
thrombosis (human)
ROlHL-22617-01
(sheep)
Studies of vasomotor control (rats)
Microcirculation in patients with diabetes
Cardiac adaptation to physical training
ROlHL-227 15-01
reflexes (dogs))
ROlHL-22778-01
ionophores
ROlHL-22801-01
(dogs)
ROlHL-22952-01
Angiotensin, hypertension and the CNS
Neural integration of the cardiovascular
Total synthesis of natural cardiotonic
Analysis of coronary artery behavior
Validation of quantitative coronary
arteriography (dogs)
** R23HL-22975-01 Dynamics of autoregulation of muscle
blood flow (dogs)
ROlHL-23171-01 Coronary collateral circulation in
myocardial ischemia (dog, pig, rat, human)
ROlHL-23239-01 Functional characteristics of pulmonary
vascular smooth muscle (dogs)
ROlHL-23267-01 Rheology and kinetics of hemoglobin S
gelation (human)
** ROlHL-23604-01 Hepatic microvascular regulatory
mechanisms (rat)
NOlHV-72924-04 Non-invasive detection of atherosclerotic
lesions (human, animals)
NOlHV-72925-04 Non-invasive detection of atherosclerotic
lesions (human, monkeys, dogs)
N01HV-72929-01 Improved detection of atherosclerosis
(human, dogs)
N01HV-72975-02 Energy converter for left ventrical assist
devices (calves)
CARDIOVASCULAR FUNCTION, BLOOD FLOW,
REACTIVE HYPEREMIA
POlHL-063 12-17 0013 Surgical cardiology - Aortocoronary
vein bypass grafting (human)
POlHL-063 14-17 0065 Immunologic mechanisms in
cardiovascular disease - Transplantation biology and
clinical transplantation
ROlHL-10384-13 Blood flow and nucleotide metabolism
(animals)
POlHL-11678-11 0043 Cardiovascular dynamics and their
control ■ Basic mechanisms of circulatory shock (dog)
ROlHL-1 1876-11 Regional myocardial blood flow and
metabolism (dogs, swine)
ROlHL-124 15-10 Evaluation of left ventricular function
(dogs, rabbits)
ROlHL-12493-10 Bioengineering analysis of microvascular
function (cats, rabbits)
ROlHL-12494-10 Continuum mechanics in biophysics
(human, animals)
ROlHL-12792 09 Local control of the microcirculation
(hamsters, rats)
ROlHL-13595-08 Renin and vascular hyper-reactivity in
hypertension (human, rats)
ROlHL-13654-08 Antilipemic regimes in peripheral
arteriosclerosis (human)
ROlHL-15231-05 Mechanisms of hemodynamic changes
during digestion (dogs)
** ROlHL-15390-12 Regulation of blood flow in the
microcirculation
CAR
ROlHL-15681-06 Coronary flow studies of partially
obstructed vessels (dogs)
POlHL-16117-05 0007 Ion movements and membranes in
cardiovascular control - Physiological and molecular
properties of ionophores (dogs, rabbits)
ROlHL-1641204 Release of nucleosides from the ischemic
heart (human, dogs)
POIHL 17421-05 0002 Regulation and exchange in the
microcirculation - Metabolic and myogenic blood flow
regulation in microcirculation (animals)
POlHL-17421-05 0004 Regulation and exchange in the
microcirculation - Localization of flow regulation in the
microcirculation (cats, human)
P50HL-17648-04 0011 Study of ischemic heart disease -
Surgical treatment for acute myocardial ischemia (human,
dogs)
P50HL-17651-04 0015 Ischemic heart disease specialized
center of research - Peripheral circulation in acute
myocardial ischemia and infarction (human)
P50HL-17670-04 0006 Study of ischemic heart disease •
Assessment of coronary artery hemodynamics and
myocardial blood flow (human)
ROlHL-17759-03 Studies of myocardial reactive hyperemia
(dogs, human)
POlHL-17813-04 0001 Lung disease and the oxygenation
of blood and tissue - Diffuse interstitial lung disease-
Pathophysiology (human, dogs)
ROlHL-17853-03
(animals)
ROlHL-17902-04
(hamsters)
ROlHL-17932-04
ROlHL-18060-04
Peripheral circulation in heart failure
Mammalian renal microcirculation
Blood flow regulation in muscle (cats)
Exercise and coronary atherosclerotic
heart disease (monkeys)
ROIHL 18468-03 The distribution of flow in the
myocardium (dog, pig)
ROlHL-18492-03 Measurement of regional coronary flow
reserve (human, dogs)
POlHL-18575-03 0001 Mechanisms of vascular changes
in hypertension - Arteries and resistahce vessels in
hypertension (pigs, rats)
ROlHL-18805-04 0005 Sudden cardiac death and the
onset of myocardial infarction - Sudden death survivors-
Radionuclide studies (human)
ROlHL-18933-03 Energy output and efficiency of left
ventricle (dog)
ROlHL-18977-03 Non-invasive diagnosis of peripheral
arterial disease (human, dogs)
ROlHL-19370-03 Coronary capillary exchange-The effects
of ischemia (dogs, sheep)
ROlHL-19937-02
infarction (dogs)
ROlHL-20399-03
mellitus (dog)
ROlHL-20598-03 The coronary vascular response to
ischemia (dogs, pigs)
ROlHL-20827-02 Effects of hypertrophy on the coronary
circulation (dogs)
Vasodilators in experimental myocardial
Vascular control in experimental diabetes
ROlHL-21034-01
occlusion (dogs)
R23HL-2I298-02
ROlHL-21657-01
hypoxia (dogs)
ROlHL-21843-01
Compensatory responses to arterial
Coronary vasomotion (dogs, pigs)
Regional non-ischemic myocardial
Ischemia, diabetes and the
microcirculation (rats, cats, hamsters)
R23HL-21914-01 Studies of vasomotor control (rats)
ROlHL-22801-01 Analysis of coronary artery behavior
(dogs)
ROlHL-23312-01 Hemodynamics and vasoactivity in renal
hypertension (human, dogs)
CARDIOVASCULAR FUNCTION, BLOOD FLOW
IMPEDANCE
SEE ALSO CARDIOVASCULAR FUNCTION, VASCULAR
RESISTANCE
** POlHL-06285-18 0157 Cardiovascular-respiratory
physiology and biochemistry - Left ventricle outflow
impedance analysis (human)
POlHL-06285-18 0158 Cardiovascular-respiratory
physiology and biochemistry - Load on myocardial
contractility (dogs)
POlHL-08682-15 0005 Regulation of the cardiovascular
system - Smooth muscle and mechanical properties of
blood vessels (dogs, human)
POlHL-10436-13 0015 A multidisciplinary study of
congenital heart disease - Fetal and neonatal
cardiovascular physiology (sheep)
ROlHL-11919-08 Pulmonary circulation in surgical heart
disease (human, dogs)
** ROlHL-12607-10 Dynamics of pulsatile blood flow (human,
dogs, rats)
** R01HL-16830-05 Non-invasive determination of aortic
blood velocities (human)
POIHL-16833-04 0009 Hemoglobin and red cell system in {
hemoglobinopathies - Rheological studies of sickled cells
(human)
Controlled intratissue release of
ROlHL-18259-03
prostaglandins
ROlHL-19256-03
control (dogs)
ROlHL-20073-02
Arterial baroreceptors in cardiovascular
Blood compatible materials by fluid
perfusion (human, dogs)
(contd)
tMtuia iwtin* iMthodoloo OR covers only general projects which preclude Indexing at the specific level.
' Oirf.tet s!;<iific«nHy to aboM subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
CAR
IIS
CAR
ROIHl 71103 01 PifimslHc mtchinlcti iludKS ol
hyp«r1tnilv« in«ii«s (do|s. iiti)
ROIHl 21188 0? Pulsitoiy w«t<r tlui and gndothtlial cell
dtsqutmition
ROIHl 2124S 02 Inlluenct ol chronic aneicist on
hyp«rtension (tils, pcimal(s)
ROIHl 212/0 01 Coiielalion ol artatial hemodynamics and
mo<phology (human)
Machanlcil Interactions between ventiicle
Unsteady How in arlerial bilurcalions
Caidiovasculai phaimacodynamics in
" R23H12146202
aitehes (dogs)
" R01H1218590I
(human)
R23HL 22309 01
immature dogs
" ROIHI 224SS0I Platelet concentration in the marginal
layer (dogs, human)
ROIHI 22801 01 Analysis ol coronary artery iMhavlor
(dogs)
ROIHI 228ISOI Regional myocardial function alter
revascularisation (dogs)
ROIHI 2289301 Evaluating arlerial disease by velocity
wave analysis (dogs, human)
CARDIOVASCULAR FUNCTION, BLOOD FLOW
OSCILLATORY
SEE ALSO CARDIOVASCULAR FUNCTION, VASOMOTION. PULSE
PRESSURE WAVES
POIHI'11310 12 9002 Mechanisms ot cardiovascular
disease Core support centralized electronic laboratory
P50HL 14192 08 0008 Specialized center ol research in
hypertension New radiographic methods-Recognition ol
renovascular hypertension (human, dog)
ROIHL 221 1302 Micro/macrovasculaturc in healing of
foot lesions (human)
ROlHL'23239-01 Functional characteristics of pulmonary
vascular smooth muscle (dogs)
CARDIOVASCULAR FUNCTION, BLOOD
PRESSURE
SEE ALSO CARDIOVASCULAR DISORDERS. HYPERTENSION
(SYSTEMIC)
SEE ALSO CARDIOVASCULAR DISORDERS. HYPOTENSION
SEE ALSO CARDIOVASCULAR DISORDERS DIAGNOSIS. BLOOD
PRESSURE GRADIENT TECHNIQUE*
SEE ALSO CARDIOVASCUUR DISORDERS DIAGNOSIS.
PLETHYSMOGRAPHY*
SEE ALSO CARDIOVASCULAR FUNCTION. BLOOD FLOW
IMPEDANCE
SEE ALSO CARDIOVASCULAR FUNCTION. VASCUUR
RESISTANCE
SEE ALSO CARDIOVASCULAR FUNCTION. VASOMOTION. PULSE
PRESSURE WAVES
ROlHL'03429-18 Central nervous system and coronary
heart disease (human)
ROlHL-04457-20 Cellular aspects of active transport (fish,
rabbits, anurans. turtles)
ROlHL-06143'18 Response of the totally denervated heart
to exercise (dogs)
POIHL'06285'18 0180 Cardiovascular-respiratory
physiology and biochemistry - Vagal C-fibers and their
influence on visceral and somatic function (animals)
P01HL-Oe28518 0181 Cardiovascular-respiratory
physiology and biochemistry - Regulation of respiration-
Role of vagus nerve (dogs)
POlHL-06835-17 0022 Cardiovascular disease - Arterial
lipogenesis from glucose in the rat
POlHL-06835-17 0034 Cardiovascular disease - Studies
of phospholipase A2 in serum (rats, dogs)
P01HL-0683S-17 0038 Cardiovascular disease - Effect of
chronic administration of angiotensin antagonist (rats)
POlHL-06835-17 0039 Cardiovascular disease -
Reversibility of vascular changes in renal hypertension
(rats)
POlHL-06835-17 0042 Cardiovascular disease -
Myocardial hypertrophy due to renal hypertension (rats)
POlHL-0683517 0044 Cardiovascular disease -
Baroreceptors In control of blood pressure during sleep
(dogs)
** POlHL-06835-17 0045 Cardiovascular disease ■ Pressure-
volume-renin relationship in human hypertension
POlHL-06835-17 0046 Cardiovascular disease - Renin
activity during salt depletion in essential hypertension
(human)
POlHL-0683517 0047 Cardiovascular disease -
Spironolactone in primary aldosteroidism (human)
POlHL-06835-17 0052 Cardiovascular disease - Aortic
distensibility (human)
*• POlHL-06835-17 0056 Cardiovascular disease ■
Angiotensin analogs-Sarcosine on arterial pressure,
aldosterone (dogs)
** ROIHL-07723-15 Reflex control of vascular capacitance in
shock
POlHL-08682-15 0015 Regulation of the cardiovascular
system - Projection of autonomic nerves onto the heart
(dog)
** POlHL-08682-15 0022 Regulation of the cardiovascular
system - Blood pressure responses and preganglionic
sympathetic outflow (cat)
** POlHL-08682-15 0023 Regulation of the cardiovascular
system • Cardiovascular control-Effects of spinal pathways
lesions (dog)
** POlHL-08682-15 0024 Regulation of the cardiovascular
system - Morphology of the spinal sympathetic system (cat)
ROIHI 09154 14 Central control ol distribution of organ
blood How (monkeys)
POIHL 104J6 IJ 0008 A multidisciplinaiy study ol
congenital hnort diseniie Physiologic consequenciis ol
chronic hypoxemia (human)
ROIHL 10612 13 0021 Humoral laclors in heart failure
and hypertension Ihe control of aldosterone secretion
(dogs)
ROIHL 11046 12 Renin, angiotensin, steroids, ions and
blood pressure (human, sheep, rabbits)
POIHL 11310 12 0056 Mechanisms of cardiovascular
disease Cardiac output response to blood pressure
reduction in infants (human)
POIHL 11310 12 0057 Mechanisms of cardiovascular
disease Blood pressure reduction after heart surgery In
adults (human)
POIHL 11310 12 0059 Mechanisms of cardiovascular
disease Contractility Acute response to diogoxin after
heart surgery (children)
POIHL 11310 12 0065 Mechanisms of cardiovascular
disease Algorithms lor arterial pressure by automatic
vasoactive agents control (human)
POIHL 11678 11 Cardiovascular dynamics and their
control
POIHL 11678 11 0001 Cardiovascular dynamics and their
control Body fluid volumes in the genesis ol hypertension
(rats, dogs)
P01HL11678-11 0027 Cardiovascular dynamics and their
control Vasopressin and thirst in control of body fluid
volumes and osmolality (dogs)
P01HL11678 11 0031 Cardiovascular dynamics and their
control - Hypertension caused by stimulation ol renal
sympathetic nerves (dogs)
POlHL-1 1678-11 0034 Cardiovascular dynamics and their
control Renal function curves in intact dogs
P01HL11678-11 0040 Cardiovascular dynamics and their
control Control of plasma potassium concentration (dogs)
POIHLI 1678-11 0059 Cardiovascular dynamics and their
control - Basic hemodynamics (dogs, rats)
POIHL 11678-11 0060 Cardiovascular dynamics and their
control - Salt and water balance in one kidney Goldblatt
hypertension (rat)
POlHL-l 1678-11 0064 Cardiovascular dynamics and their
control - Renal medulla-Control of renal hemodynamics.
electrolyte excretion (dogs)
POlHL-11678-11 0065 Cardiovascular dynamics and their
control - Body fluid volumes in the genesis of hypertension
(dogs)
POlHL-11678 11 0069 Cardiovascular dynamics and their
control - Nervous control of the cirulation (dogs)
R01HL-12322-10 Extrinsic factors influencing myocardial
performance (dogs, swine)
P01HL12373-10 0013 Cardiopulmonary physiology and
pathophysiology - Effects of cardiovascular drugs on left
ventricular function (dogs)
ROlHL-1249310 Bioengineering analysis of microvascular
function (cats, rabbits)
ROIHL-12677'IO Surgical physiologic studies of isolated
kidneys (dogs, rats)
POlHL-13262-07 0024 Arterial wall in atherosclerosis ■
Serial ocular changes in arteriosclerosis and hypertension
POlHL-13737-07 0013 Assisted circulation - Incorporation
of sensors (human, dogs)
P50HL-1414105 0001 SCOR for atherosclerosis in
childhood - Clinical implications (infants and children)
P50HL-141 59-08 0018 Specialized center of research in
hypertension ■ Sympathetic nervous system in hypertension
(rats)
P50HL141 59-08 0021 Specialized center of research in
hypertension - Genetic studies of the physiology of
hypertension (human, rats)
P50HL14164-07 0041 A/S SCOR-Comparative and
experimental atherosclerosis - Nonhuman primate pediatric
atherosclerosis risk factor
P50HL-14164-07 0042 A/S SCOR-Comparative and
experimental atherosclerosis - Comparative cardiology
laboratory (monkeys)
ROlHL-14306-07 Quantification of arterial pressure control
(dogs)
POlHL-14388-07 0156 Regulation of the circulation in
pathological states ■ Blood pressure with drinking to
intracranial angiotensin II injections (rats)
POIHL-14388-07 0159 Regulation of the circulation in
pathological states ■ Early drug and diet interventions and
blood pressure development (rats)
P01HL14388-07 0185 Regulation of the circulation in
pathological states - Reflex control of venous tone (human,
rabbits, dogs)
POlHL-14388-07 0193 Regulation of the circulation in
pathological states - Ontogenesis of central nervous system
amines in hypertension (rats)
POlHL-14388-07 0195 Regulation of the circulation in
pathological states ■ General review of potential
pathophysiologic factors in spontaneous hypertension
P01HL14388-07 0196 Regulation of the circulation in
pathological states ■ Altered vascular responsiveness in
spontaneous hypertension (rats)
POIHL- 143 88-07 0202 Regulation of the circulation in
pathological states ■ Development of hypertension in
spontaneously hypertensive rats
POIHI 14)88 0/ 0704 Regulilion ot the circulation in
palhologicil tlatei Rellei control ol vatcular rtiiitanct
in \ponlan«ouily hypttrtentrve raU
POIHI 14388 0/ 070/ Regulalion ol lhi> circulation m
pathological italei Brain and renin «ngioten*,ion
interaction in ^ponlaneou*. hyparteoMon (ratt)
POIHI 14388 0/ 0708 Regulation ol the circulation in
pathological states Baioreceploi rellei function in normal
and hypertensive man
POIHI 14388 0/ 0710 Regulation of the circulation in
pathological stales Iflects ol dietary sodium on blood
pressure and vascular reactivity
POIHL 14388 0/ 0719 Regulation ol the circulation in
pathological states Myocardial Ischemia and infarction in
animals (dogs)
POIHL 143880/ 077?
pathological states
hypertension (rats)
POIHL 143880/ 0773
pathological states
(rats)
POIHL 1438807 0733
pathological states
Regulation ol the circulation in
Renal perfusion pressure in
Regulation ol the circulation in
Kallikrein kinin system in hypertension
*Exdwles mitine methodotogy OR covers only general projects which preclude indexing
**Oriented significanthf to above subject.
at the specific level
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number
Regulation of the circulation in
Pressure How relationships after
regression ol experimental atherosclerosis
POIHL 14414 07 0008 Environmental influences on
cardiorespiratory and cellular functions Energetics of
swimming (human)
ROIHL 1456007 Hypertension produced by sympathetic
dysfunction (human, rats)
P50HL 15103 07 0001 A/S SCOR-Early natural history ol
arteriosclerosis Clinical research- Bogalusa heart study
(children)
ROIHL 15174-06 CV disease epidemiology-Second
generation studies (human)
POlHL-15194-07 0019 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation, bypass
grafts and diastolic driving pressure (human, dogs)
R01HL15307-06 Central nervous control of renin and
blood pressure (dogs)
ROIHL- 15390- 12 Regulation of blood flow in the
microcirculation
ROIHL 15447-06 Vascular role of prostaglandin and cyclic
nucleotides (rats)
R01HL1544806 Surgical and metabolic aspects of
venous grafts, (dogs, monkeys, rabbits)
ROIHL- 163 1505 Analysis of interaction between CNS
vasomotor systems (cats, rats)
ROlHL-16648-16 Integrated control of cardiovascular
activity (cats)
P01HL16910-05 0005 Regulation of the peripheral
circulation - Control of circulation by baroreceptor and
chemoreceptor reflexes (dog, monkey)
POIHL 1691006 0007 Regulation of the peripheral
circulation - CNS-Behavioral influences on circulation
(baboons)
POIHL- 169 10-05 0008 Regulation of the peripheral
circulation - Circulation to bone (dogs, baboons)
ROlHL-1691604 0011 The role of albumins in lung water
accumulation - Whole body distribution and exchange of
albumin (rabbits, human, monkeys)
POlHL-17421-05 0002 Regulation and exchange in the
microcirculation - Metabolic and myogenic blood flow
regulation in microcirculation (animals)
P01HL17421-05 0004 Regulation and exchange in the
microcirculation Localization of flow regulation in the
microcirculation (cats, human)
POlHL-17421-05 0007 Regulation and exchange in the
microcirculation ■ Core facilities-Fluorometric measurement
methods for microcirculation
ROlHL-17487-04 Adrenergic-vasoregulation interactions in
hypertension (human)
R01HL17591-03 Development of electromagnetic
rheoangiography (human, dogs)
ROlHL-17604-03 Wearable blood pressure and ECG
recording system
ROlHL-17721-04 Effect of sex hormones on vascular
connective tissue (rats)
POlHL-17731-04 0001 Physiological basis of pulmonary
disease - Mechanisms of blood flow and ventilation (dogs)
POlHL-17731-04 0002 Physiological basis of pulmonary
disease - Biomechanics of the lung (frogs, cats)
ROIHL- 17759-03 Studies of myocardial reactive hyperemia
(dogs, human)
POlHL-17813-04 0008 Lung disease and the oxygenation
of blood and tissue - Pulmonary regulation of systemic
blood pressure (human, rabbits, rats)
ROlHL-17847-04 Cardiovascular and renal functions of
marmots
POlHL-1787104 Kidney, sodium, cardiac output, arterioles
and hypertension
POlHL-17871-04 0009 Kidney, sodium, cardiac output,
arterioles and hypertension ■ Kidney, sodium, cardiac
output, arterioles and hypertension
ROlHL-17958-04 Circulatory effects of operant
cardiovascular control (baboons)
ROlHL-17969-04 Function and structure of semilunar
valves (dogs)
ROIHL- 17970-04 Vascular effects of inhibitory behavioral
adaptations (dogs)
R01HL18050-04 Mechanisms of cardiovascular
teratogenesis (chick embryo) k embryo)
(contd)
CAR
Behavioral tactics for clinical cardiac
ROlHL-18096-04 Vasoactive agents in splanchnic viscera
(primates, dogs)
POlHL-18208-04 0004 Center for the study of blood cell
rheology ■ Splenic microcirculation (rats, mice)
P50HL-18323-04 0046 SCOR hypertension center -
Coronary artery bypass surgery-Associated hypertension
(human)
ROlHL-18454-03 Maximal exercise testing in
hyperlipidemic children
ROlHL-1857903 Vasoactive hormones and blood pressure
regulation (dogs, rats, rabbits)
ROlHL-18660-03 Neurotransmitter receptors in human
erythrocytes
ROlHL-18814-03
control (human)
ROlHL-18823-02 Physiological correlates of conditioned
blood pressure (human)
ROlHL-18845-04 Regulation of renal circulation and salt
excretion (rats, dogs)
R01HL18866-02 Microvascular flovi, volume, and
reactivity (rats, cats)
ROlHL-18923-02 Steroid-induced hyperlipidemia and
hypertension (human, rats)
ROlHL-18947-02 Indirect mean arterial pressure
(mammals)
POIHL 18974-03 0001 Experimental neurogenic
hypertension program - Central neural systems regulating
arterial pressure (rabbits)
POlHL-18974-03 0006 Experimental neurogenic
hypertension program - Model of sustained arterial
hypertension (cats)
R01HL-19039C3 Circulation studies by one vs two circuit
model (dogs)
ROlHL-19134-04 Angiotensin, prostaglandins, adrenergic
interactions (rats, rabbits)
P50HL19153-02 0001 SCOR -Pulmonary edemas -Eitology.
pathogenesis - Prostaglandins and the lung circulation
(sheep)
P50HL-19153-02 0002 SCOR -Pulmonary edemas-Eitology,
pathogenesis - Lung fluid dynamics -Classical mediators
and their inhibitors (sheep)
P50HL19153-02 0003 SCOR-Pulmonary edemas-Eitology,
pathogenesis - Possible inhibitors of mediator release and
pulmonary vascular response (sheep)
ROlHL-19203-03 Surgical approach to congenital heart
diseases (dogs, primates)
ROlHL-19209-03 Role of ADH in experimental renal
hypertension (dogs, rats)
R01HL19256-03 Arterial baroreceptors in cardiovascular
control (dogs)
ROlHL-19257-03 Cardiovascular adjustment to behavioral
stress (dog)
P50HL-19362-02 0011 A/S SCOR-Atherosclerosis in
nonhuman primates ■ Chronic hypertension induced by
operant conditioning techniques (baboon)
ROlHL-19398-03 Regional conduction abnormalities and
arrhythmias (dogs)
* ROlHL-19467-03 Regulation of blood pressure (rats, dogs)
R01HL1951703 Synthesis of inhibitors for the study of
renal renin (dogs, monkeys)
ROlHL-19568-03 Hypertension-Analysis of drug and
behavioral therapies (human)
ROlHL-19677-03 Venous structure and function (dogs)
ROlHL-19680-01 Cardiac correlates of behavioral stress in
animals (dog)
POIHL 1971702 0008 Response of the lung to injury
Experimental models of lung disease
ROlHL-19839-09 Factors in youth predisposing to chronic
diseases (former college students)
ROlHL-19844-02 Behavioral control of essential
hypertension (human)
'* ROlHL-19858-03 UMMC -Blood pressure precursors and
consequences (human)
ROlHL-19859-03 Epidemiological studies, precursors of
hypertension (human)
VI ROIHL 19864-03 Blood pressure of children and young
adults
** ROlHL-19864-03 0001 Blood pressure of children and
young adults - Follow up of students from Dormont,
Pennsylvania
** ROIHL 19864-03 0003 Blood pressure of children and
young adults Heart rate and blood pressure -Consistency
in infancy (human)
ROIHL 19869-03 Antecedents of adolescent hypertension
(human)
*• ROIHL 1987003 Hypertensive progeny-Physical and
humoral precursor search
** ROlHL-19922 03 Childhood determinants of blood pressure
" ROlHL-19930-03 A prospective study- Blood pressure in
newborn twins
ROlHL-19956 03
(human)
•* R01HL19984 02 Blood pressure and immunogenetic
factors in the young (human)
** ROIHL 20005 03 Factors in blood pressure levels of
children
ROlHL-2017602 Biochemistry and genetics of salt
hypertension (rats)
ROlHL-20189 01 Effects of renin on atherogenesis
(rabbits)
*• ROlHL-20194-01 Brain catecholamines in control of blood
pressure (rats)
High blood pressure in the young
116
ROlHL-202 19-02 Cryopreservation of the isolated heart
(rats)
ROlHL-20328-01 Noninvasive assessment of autonomic
cardiac control (dogs)
ROlHL-20371-02 Intravascular redistribution of blood
volume (dogs)
ROlHL-20439-02 Effects of insulin on neurovascular
transmission (human, rats, rabbits, hamsters)
ROlHL-20508-03 Diabetes, hyperglycemia and
cardiovascular disease (human)
ROlHL-20572-02 0007 Hemodynamic relations to
metabolism in hypertension - Drug effects on cardiac
function and hypertropy (rats)
ROlHL-20572-02 0008 Hemodynamic relations to
metabolism in hypertension - Role of nervous system in
hemodynamic function
ROlHL-20605-02 Microvascular responses during intestinal
absorption (rats)
ROlHL-2066202 Physical activity, fitness and
epidemiology of CHD
ROlHL-20663-02 Regulation of skin blood flow in man
' ROlHL-20864-01 Postnatal maturation of cardiovascular
regulatory system (minipig)
ROlHL-208 78-02 Cellular aspects of lung injury (rats,
rabbits)
ROlHL-21071-02 Mechanisms of hypertension in
coarctation of the aorta (dog)
R23HL-21332-02 Pulsatile regulation of flow in the
microcirculation (cats)
' R23HL-2 1382-02 Effect of pressure on renal blood flow
and function (dogs)
ROlHL-21532-02 Cardiovascular homeostasis and learning
(frogs, rats, human)
R23HL-21559-01 Oxygen supply and blood flow through
aortic vasa vasorum (dogs)
* ROlHL-21796-01 Applied pulsatile hemodynamics in
vascular surgery (dogs)
ROlHL-21817-01 Catecholamines, blood pressure and
circulation
R23HL-21914-01
ROlHL-22032-01
(human)
* ROlHL-2206902
(dogs)
ROlHL-22113-02
foot lesions (human)
ROlHL-221 18-02
mellitus
R01HL-222Z3-01
models)
* ROlHL-22225-01 Hormonal regulation of blood pressure
and blood flow (human, animals)
ROlHL-22261-01 Compliance of fluid spaces in advancing
hypertension (rats)
* ROlHL-2228801
function (mice)
ROlHL-22298-02
R23HL-22309-01
immature dogs
ROlHL-22378-01 Psyco-somatic predictors of CHD in
adolescence (human)
ROlHL-22406-01 Isobaric vascular bubbles and
decompression sickness (goats, models)
•♦ ROlHL-224 17-01
(dogs)
Studies of vasomotor control (rats)
Cardiovascular events in hypertensives
Experimental renal arterial hypertension
Micro/macrovasculature in healing of
in)
Microcirculation in patieryts with diabetes
The cardiopulmonary junction (dogs.
Renin and precursors-Structure and
Origins of hypertension (human)
Cardiovascular pharmacodynamics in
Microprocessors in medical applications
Neural control of cardiorespiratory
Angiotensin, hypertension and the CNS
Cardiovascular effects from visceral
Neural integration of the cardiovascular
Analysis of coronary artery behavior
ROlHL-224 18-01
function (cats)
ROlHL-22617-01
(sheep)
R23HL-22669-01
afferents (dogs)
ROlHL-2271501
reflexes (dogs))
ROlHL-22801-01
(dogs)
ROlHL-22854-01 Non-invasive blood pressure
measurement (rats)
R23HL-22933-01 Transvascular fluid and protein exchange
in the lung (sheep)
ROlHL-22952-01 Validation of quantitative coronary
arteriography (dogs)
R23HL-229 75-01 Dynamics of autoregulation of muscle
blood flow (dogs)
ROlHL-23171-01 Coronary collateral circulation in
myocardial ischemia (dog, pig, rat, human)
ROlHL-23211-01
(rat, dog, sheep)
ROlHL-23603-01
disease (rats)
NOlHR-62920-02
Active normoxic pulmonary vasodilatation
Morphogenesis of hypertensive vascular
Noninvasive diagnosis of pulmonary
hypertension (dog. human)
CARDIOVASCULAR FUNCTION, BLOOD VOLUME
SEE ALSO CARDIOVASCULAR DISORDERS, HYPERVOLEMIA
SEE ALSO CARDIOVASCULAR DISORDERS, HYPOVOLEMIA
SEE ALSO CARDIOVASCULAR DISORDERS DIAGNOSIS.
PLETHYSMOGRAPHY*
SEE ALSO HEART FUNCTION. INTRACARDIAC VOLUME
N01HI02216-10 To develop biological flow NMR concept
(human, mammals non human)
ROlHL-00487-29 Vasomotor tone and venous return
(human, dogs, monkeys )
CAR
POlHL-04664-18 0001 Cardiovascular and lung dynamics
- X-ray projection image videodensitometry (dogs)
POlHL-06835-17 0045 Cardiovascular disease - Pressure-
volume-renin relationship in human hypertension
POlHL-06835-17 0046 Cardiovascular disease - Renin
activity during salt depletion in essential hypertension
(human)
POlHL-06835 17 0051 Cardiovascular disease -
Cardiopulmonary volume in hypertension (human)
POlHL-06835-17 0059 Cardiovascular disease -
Metyrapone-induced hypertension in dog
R01HL07723-15 Reflex control of vascular capacitance in
shock
POlHL-07896-15 0014 Environmental biomedical research
program - Mechanisms of respiration and circulation
(human, dogs)
POlHL-08682-15 0026 Regulation of the cardiovascular
system - Hypertension-High renin vs low renin (dog)
POlHL-08682-15 0038 Regulation of the cardiovascular
system - Control of pulmonary circulation (dogs)
POlHL-08899-14 0080 Tolerance to respiratory gases in
health and disease - Dynamic quantitation of continuous
isobaric gas embolization
ROlHL-09154-14 Central control of distribution of organ
blood flow (monkeys)
P01HL10342-13 0006 The integrated function of
respiration and circulation - Lung inflation effects on
pulmonary vasculature and interstitial space (dogs)
P01HL10342-13 0028 The integrated function of
respiration and circulation ■ Mediator release,
hemodynamics and respiratory function in anaphylaxis
(dogs)
* R01HL10622-12 Volumes and compliance of pulmonary
circulation (human, dogs)
POlHL-11310-12 0060 Mechanisms of cardiovascular
disease Effect of left atrium on the circulation -Simulation
POlHL-1 1678-11 0001 Cardiovascular dynamics and their
control - Body fluid volumes in the genesis of hypertension
(rats, dogs)
* P01HL1167811 0027 Cardiovascular dynamics and their
control - Vasopressin and thirst in control of body fluid
volumes and osmolality (dogs)
* POlHL-11678-11 0040 Cardiovascular dynamics and their
control - Control of plasma potassium concentration (dogs)
POlHL-1167811 0043 Cardiovascular dynamics and their
control - Basic mechanisms of circulatory shock (dog)
POlHL-11678-11 0057 Cardiovascular dynamics and their
control - Return of urine to circulation using cystico-caval
shunt (dogs)
POlHL-11678-11 0059 Cardiovascular dynamics and thelr|
control • Basic hemodynamics (dogs, rats)
* POlHL-1 1678-11 0065 Cardiovascular dynamics and their|
control - Body fluid volumes in the genesis of hypertension
(dogs)
POlHL-1 1678-11 0068 Cardiovascular dynamics and theirj
control - Basic hemodynamics (rats, dogs)
ROlHL-12777-09 Mechanisms in cardiac performance
(dogs, human)
R01HL13237-09 Erythrocytes during early development
(human, animals)
ROlHL-13427-09
dogs)
ROlHL-1362308
ROlHL-13634-08
POlHL-13851-16
Neural control of blood volume (monkeys,!
Atrial receptors (dogs)
Renal hypertension in pregnancy (sheep)
Cyclotron produced isotopes in biology
and medicine (human, animals)
P50HL14187-07 0015 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses -
Pathophysiologic responses of pulmonary capillary bed
(dog. human)
P50HL-142 18-07 0017 Pulmonary SCOR-Newborn lung
center - Transvascular fluid exchange, vasoactive mediatoi
in RDS (sheep, cat)
Regulation of the circulation in
Reflex control of venous tone (human,
Regulation of the circulation in
Idiopathic cyclic edema
Systems analysis of baroreflex (dogs)
Survival value of physiological response^
POlHL-14388-07 0185
pathological states
rabbits, dogs)
POlHL-14388-07 0232
pathological states
ROlHL-14529-07
ROlHL-14693-07
to hypoxia (dogs)
POlHL-14985-07 0005 Adaptation to hypoxia - Control
mechanisms in the pulmonary microcirculation (animals)
ROlHL-15307-06 Central nervous control of renin and
blood pressure (dogs)
ROlHL-15655-05 Blood flow and gas exchange in placenta
and lungs (sheep) rabbits)
R01HL16656-06 Left ventricular function in exercise
(dogs)
ROlHL-16658-05 Intrarenal regulation of sodium
reabsorption
POlHL-1691005 0006 Regulation of the peripheral
circulation - Regulation of blood flow distribution (baboons.
dogs)
R01HL16916-04 0002 The role of albumins in lung water
accumulation • Lung water balance-Forces, models and
albumin concentrations (rabbits, dogs)
ROIHL 17503-03 Vascular bubbles in decompression
sickness (minipig, dog, goat)
P50HL-17655-04 0027 Study of ischemic heart disease ■
Positron imaging of regional myocardial perfusion (human.
dog)
(contd)
•Excludes routine methodokigy OR covers only general projects which preclude indexing
"OciefltMl signifiuntty to above subject
at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
CAR
1 17
CAR
PbOHl 1/669 04 0013 Ischtmic h«ai< itiseuMi cunlii
(SCOR) Euicist In palMnts with ischamic hitnil diseijt
ROIHI 17/68 04 Dtvalopmint of collateial venlilalion
(do|i. Iish. horjas)
POIHL 1/81304 0001 Lung disaase and lh« oiytonalion
of blood and tiisua Dltlusa inleislilial lung disease
Pathophysiology (human, dogs)
ROIHL W902 04 Mammalian tenal miciocifculation
(hamstais)
ROIHL 1/931 04 Normalized body surface potential maps
(children)
ROIHL 1/9S4 03 Narcotics and the circulation (human.
dogs. pigs, monkeys)
ROIHL 1801004 Capillary transport of large molecules
(dogs, sheep)
PSOHL 18318 03 0001 Pathogenesis and complications of
hypertension Core clinical program
P50HL 1831803 0007 Pathogenesis and complications of
hypertension Humoral factors and renal function in
experimental hypertension (rats)
PSOHL 1831803 0010 Pathogenesis and complications of
hypertension Hemodynamics in mineralocorticold and low
renin hypertension (human)
P50HL 1831803 0011 Pathogenesis and complications o(
hypertension Adrenergic function Renin and
mineralocorticold activity (human)
P50HL 1832304 0042 SCOR hypertension center Blood
viscosity and blood volume in hypertensive disease
(human, dog)
POIHL 18575 03 0002 Mechanisms of vascular changes
in hypertension Endocrines. electrolytes, and
hemodynamics in hypertension (pigs)
ROIHL 18579-03 Vasoactive hormones and blood pressure
regulation (dogs. rats, rabbits)
R01HL18624 03 Study of kinins in hypertension and other
diseases (human)
ROlHL-18866-02 Microvascular flow, volume, and
reactivity (rats, cats)
ROlHL'18882-02 Hormones in hypertension (human)
ROIHL 18891 02 Electrolyte intake and blood pressure in
hypertension (human)
R01HL19039-03 Circulation studies by one vs two circuit
model (dogs)
P5OHL19155-02 0001 Pathophysiology of pulmonary
edema - Pulmonary edema study unit (human, dog)
ROlHL'19203-03 Surgical approach to congenital heart
diseases (dogs, primates)
R01HL1920903 Role of ADH in experimental renal
hypertension (dogs, rats)
R01HL1929803 Pulmonary hemodynamics (dogs, cats)
ROlHL-19486'03 Dipole moment measurement of cardiac
mass (rabbits, pigs)
P01HL19737-02 0010 Cellular and molecular aspects of
respiratory physiology - Effects of pulsatile flow and volume
on capillary exchanges (dogs, rats)
RClHL-20177-02 Effects of erythrocyte deformability on
tissue perfusion (rats)
ROlHL-2037102 Intravascular redistribution of blood
volume (dogs)
POlHL-20581-01 0005 Vascular neuroeftector
mechanisms in health and disease ■ Changes in the
neuroetfector mechanism in hypertension (rabbits)
ROlHL-20607-02 Tissue analysis by mass spectrometer
(dogs)
RCIHL-20634-01 Blood volume and venous return in
thermal strain (human)
ROlHL-20979-02 A novel pulsed Doppler flowmeter (dogs)
ROlHL-21094-01 Arterial baroreceptors and renal function
(dogs)
R23HL-21168-01 Hypoxemic respiratory failure-Physiologic
evaluation (human, dogs)
ROlHL-21245'02 Influence of chronic exercise on
hypertension (rats, primates)
ROlHL-21282-01
animals (rats)
ROlHL-2143602
(cats)
ROlHL-21498-02
R01HL-21673-01
Dynamics of interstitial space in whole
Autonomic control of renal function
Pathophysiology of edema (rats, cats)
Pathophysiology of venous changes in
hypertension (rats, rabbits, human, dogs)
ROlHL-21893-01 Blood volume distribution in hypertension
(human)
ROlHL-2 1948-01 Capillary, tissue volume and lymph flow
in lung edema (sheep, cattle)
ROlHL-2226101 Compliance of fluid spaces in advancing
hypertension (rats)
ROlHL-22371-01 Vascular changes in lung exposed to
radiation
ROIHL 22482-01
excretion (dogs)
ROlHL-22506-01
hypertensions
ROlHL-22917-01 Microvascular pressures in the intact
beating heart (rabbits)
R23HL-22933-01 Transvascular fluid and protein exchange
in the lung (sheep)
ROlHL-22977-01 Role of vasoconstrictor mechanisms in
heart failure (human, dogs)
ROlHL-230 15-01 Mechanisms of hypo-oncotic pulmonary
edema (human, dogs)
ROlHL-23201-01 Mechanisms of hypertension (human,
rats)
Circulatory hemodynamics and sodium
Hemodynamics of the clinical
ROIHI 2J2J9U1 lunctiunal chaiacleriitics of pulmonary
vascular smooth muscle (dogs)
ROIHL 23317 01 Hemodynamics and vaioactivity In renal
hypertension (human, dogs)
ROIHI 23602 01 Physiology of renin, aldosterone and
prostaglandin (human, rats, dogs)
CARDIOVASCULAR FUNCTION, VASCULAR
RESISTANCE
SEE ALSO CARDIOVASCULAR FUNCTION. BLOOD FLOW
IMPEDANCE
ROIHL 00487 29 Vasomotor tone and venous return
(human, dogs, monkeys )
POIHL 04664 18 0009 Cardiovascular and lung dynamics
Biological signal and image processing techniques (dogs)
ROIHL 05883 18 0002 Reflex control of resistance and
capacitance vessels Adenosine, adenine nucleotides and
vascular smooth muscle (dog)
POIHL 06285 18 0128 Cardiovascular respiratory
physiology and biochemistry Pulmonary circulation in fetal
lambs in utero
** P01HL06312 17 0046 Surgical cardiology The
relationship of prostaglandins to heart disease
** P01HL06312 17 0049 Surgical cardiology Long term
pulmonary vascular resistance (human)
P01HL06664 17 0010 Cardiopulmonary function in
remediable vascular disease Ischemia and acute renal
failure (rats)
P01HL06664 17 0034 Cardiopulmonaiy function in
remediable vascular disease - Role of hyperosmolar agents
in ischemic heart disease (dogs)
POlHL-06835-17 0040 Cardiovascular disease Benign
and malignant phase of renal hypertension (dogs)
P01HL-0683S-17 0053 Cardiovascular disease -
Vasodilating drugs (human)
P01HL06835-17 0059 Cardiovascular disease ■
Metyrapone-induced hypertension in dog
P01HL-07896-1S 0014 Environmental biomedical research
program - Mechanisms of respiration and circulation
(human, dogs)
" ROlHL-08570 15 Pharmacologic and reflex influence on
vascular tone (dogs, rabbits)
POlHL-08682-15 0023 Regulation of the cardiovascular
system - Cardiovascular control -Effects of spinal pathways
lesions (dog)
POlHL-08682-15 0026 Regulation of the cardiovascular
system - Hypertension -High renin vs low renin (dog)
POlHL-08682-15 0038 Regulation of the cardiovascular
system - Control of pulmonary circulation (dogs)
POlHL-0880515 0049 Regulation of ventilation and
pulmonary circulation - Pulmonary hypertension produced
by Dirofilaria immitis in the dog
ROlHL-1000913 Regional lung function in man
POlHL-10342-13 0027 The integrated function of
respiration and circulation - Control of respiration -
Cardiovascular adjustment to hypoxia and carbon monoxide
POlHL-10436-13 0002 A multidlsciplinary study of
congenital heart disease - Myocardial performance,
metabolism and ultrastructure (human, cats, rats)
P01HL10436-13 0015 A multidlsciplinary study of
congenital heart disease - Fetal and neonatal
cardiovascular physiology (sheep)
ROlHL-10834-09 Fetal and neonatal pulmonary circulation
(goats)
ROlHL-10881-13 Structure and function of
microcirculation (hamsters, rats, cats, dogs)
ROlHL-10942-09 Study of genetic hypertension in rats
P01HL-n31012 0061 Mechanisms of cardiovascular
disease - Computer simulation of transposition of great
arteries in infants
POlHL-11678-11 0001 Cardiovascular dynamics and their
control - Body fluid volumes in the genesis of hypertension
(rats, dogs)
POlHL-11678-11 0051 Cardiovascular dynamics and their
control - Transient glomerular filtration dynamics (dogs)
POlHL-1167811 0058 Cardiovascular dynamics and their
control - Overall control of the circulation-Computer
analysis
POlHL-1 1678-11 0063 Cardiovascular dynamics and their
control - Renin-angiotensin system-Control of renal
hemodynamics, electrolyte excretion
•* POlHL-11678-11 0068 Cardiovascular dynamics and their
control - Basic hemodynamics (rats, dogs)
ROlHL-1 17 17-09 Effect of stenotic obstructions on flow in
arteries (dogs)
ROlHL-1 1802-10 Cardiovascular surgical research (dogs,
sheep, swine, cats, monkeys)
ROIHLI 19 19-08 Pulmonary circulation in surgical heart
disease (human, dogs)
ROlHL-12322-10 Extrinsic factors influencing myocardial
performance (dogs, swine)
ROlHL-12415-10 Evaluation of left ventricular function
(dogs, rabbits)
P01HL12738-10 OUl Physiologic pharmacology and its
clinical applications - Cardiovascular pharmacology (dogs)
POlHL-1310809 0020 Clinical heart transplantation ■
Autonomic neural studies in the denervated heart (human)
P01HL-13ia8-09 0022 Clinical heart transplantation ■
Studies on cardiac receptors (human)
ROlHL-13634-08 Renal hypertension in pregnancy (sheep)
POIHL 13737-07 0009 Assisted circulation ■ Analytical
models
P50HI 14214 0/ UU7I< Nirwbuiii Ium( (i^i.lrr lui hyalint
mambrint diiaaie Htmodynamic tludiat of HMD
Proitailtndint production and bloch«r« (lambtl
P50HI 14230 0/ 0088 A/S SCON (ipidi. alhrroicltrotli
and thrombosis Coronary risk lactort in tchool childran-
The Muscatine study
POIHI 14388 0/ 0165 Nagulation of th« circulation in
pathological states Vascular resistance in experimental
atherosclerosis in Rhesus monkoyt
POIHI 14388 0/ 0166 Regulation of th« circulation m
pathological states Elastic changes in abdominal aorta
with atherosclerosis (Rhesus monkeys)
POIHI 14388 0/ 0186 Regulation ol (he circulation in
pathological stales Angiolcnsion in modulation ol
neurogenic vasoconstriction
POIHL 14388 0/ 019/ Regulation of the circulation in
pathological states Altered vascular reactivity in
pathogenesis of spontaneous hypertension (ralsi
POIHL 14388 07 0198 Regulation of the circulation in
pathological states Humoral factors in vascular reactivity
in spontaneously hypertensive rats
POIHL 14388 0/ 0199 Regulation of the circulation in
pathological states Adrenergic stimulation in
spontaneously hypertensive rats
POIHL 14388 0/ 020) Regulation of the circulation in
pathological states Central sympathetic discharge in
spontaneously hypertensive rats
POIHL 14388 07 0202 Regulation of the circulation in
pathological states Development of hypertension in
spontaneously hypertensive rats
POIHL 14388 07 0203 Regulation of the circulation in
pathological states Activation of sympathetic nervous
systems in spontaneously hyperactive rats
POIHL 14388-07 0204 Regulation of the circulation in
pathological states Reflex control of vascular resistance
in spontaneously hypertensive rats
POIHL 1438807 0209 Regulation of the circulation in
pathological states - Neural regulation of vascular
resistance in human hypertension
POlHL-14388-07 0210 Regulation of the circulation in
pathological states Effects of dietary sodium on blood
pressure and vascular reactivity
POlHL-14414-07 0008 Environmental influences on
cardiorespiratory and cellular functions - Energetics of
swimming (human)
ROlHL-14529-07 Systems analysis of baroreflex (dogs)
ROlHL-14560-07 Hypertension produced by sympathetic
dysfunction (human, rats)
ROIHL 14944-07 Renal vascular reactivity in hypertensive
patient
POlHL-1498507 0003 Adaptation to hypoxia - Hypoxia
and oxygen transport (human, dogs)
POlHL-14985 07 0015 Adaptation to hypoxia Pregnancy
at high altitude (human, animals)
ROIHL 15231-05 Mechanisms of hemodynamic changes
during digestion (dogs)
R01HL-15270-06 Local mechanical properties of the aortic
tissue (dogs, pigs)
R01HL15307-05 Central nervous control of renin and
blood pressure (dogs)
ROlHL-1541606 Cardiovascular control in normal and
disease states (dogs, baboons)
ROlHL-15522-06 Influence of mannitol on ischemia
cardiac muscle (dogs, cats, rats)
ROlHL-15562-05 Regulation of skeletal muscle blood flow
(dogs)
R01HLI5580-06 Humoral control of pulmonary and
systemic circulation (animals)
ROlHL-15676-06 The role of occult myocardial failure in
human shock (human, dogs)
ROlHL-1569406 Pulmonary factors in circulatory
regulation
ROlHL-16094-06 The dynamics of microcirculatory function
(dogs)
Surgery and non-obstructive
Cardiopulmonary resuscitation
ROlHL-16292-05 0017
coronary insufficiency
(human)
ROlHL-15292-05 0018
coronary insufficiency
'Excludes rautine ine(hodok)gy OR cavers only general projects which preclude indexing at the specific level.
"Oiiented significantly to above subiect.
Surgery and nonobstructive
Unavoidable subendocardial
perfusion caused by venting and hypothermia (dogs)
ROlHL-16292-05 0019 Surgery and non obstructive
coronary insufficiency - Distortion of subendocardial vessels
in infant hearts (dogs)
R01HL16292-05 0021 Surgery and non-obstructive
coronary insufficiency - Pulsatile assistance on
subendocardial perfusion during bypass (dogs)
R01HL16328-06 Membrane electrical properties of
vascular muscle (human, animals)
ROlHL-16511-04 Sympathetic afferent activity of cardiac
origin (dogs, monkeys)
ROlHL-16648-16
activity (cats)
R01HL-16656-06
(dogs)
R01HL16760-05
(dogs)
POlHL-16851-04 0009 Human red cell membrane in
health and disease - Blood cell properties in circulatory
regulation (dogs, rabbits)
P01HL16910-05 0002 Regulation of the peripheral
circulation - Coronary circulation (dogs)
(contd)
Integrated control of cardiovascular
Left ventricular function in exercise
Dynamic control of coronary blood flow
M Grant has subprojects descnbing specific research aspects
See Appendix for investigator's name and grant number.
CAR
POlHL-16910-05 0006 Regulation of the peripheral
circulation Regulation of blood flow distribution (baboons,
dogs)
P60HL-17269-04 0023 National heart and blood vessel
research and demonstration center ■ Cardiovascular
pharmacology -Ischemia, shock and heart failure (dog, cat.
rat)
R01HL17335-05 Contractile properties of hypertensive
arterioles (rats)
ROlHL-17366-05 Mechanisms in the production of renal
hypertension (rabbits, dogs)
ROlHL-17403-03 Metabolic control of cardiac output
(dogs)
POlHL-17417-05 0005 Experimental lung transplantation
- Lung transplantation in bilateral emphysema (dogs)
ROlHL-17628-03 Pulsatile pressure-flow dynamics (dogs)
P50HL-17646-04 0013 Study of ischemic heart disease -
Maintenance of myocardial vascular Integrity after
revascularization (dogs)
P50HL-17646-04 0014 Study of ischemic heart disease -
Progression of ischemic injury in conscious dogs (also
rabbits)
P50HL-1765104 0015 Ischemic heart disease specialized
center of research ■ Peripheral circulation in acute
myocardial ischemia and infarction (human)
P50HL-17651-04 0044 Ischemic heart disease specialized
center of research - Limb blood flow after myocardial
revascularization (human)
P50HL-17651-04 0045 Ischemic heart disease specialized
center of research - Peripheral vascular studies-
Pharmacology (dogs, human)
P50HL-17655-04 0003 Study of ischemic heart disease -
Cardiopulmonary resuscitation (human, dog)
P50HL17665-04 0012 Study of ischemic heart disease ■
Myocardial ischemia-Cardiovascular performance in the
conscious baboon and dog
P50HL-17665-04 0021 Study of ischemic heart disease •
Identification, prevention-Myocardial ischemia in
cardiopulmonary bypass (dog)
P50HL-17665-04 0026 Study of ischemic heart disease -
Anesthesia-Myocardial ischemia and hemodynamics in
coronary disease (human)
P50HL- 1766 7-04 0022 Study of ischemic heart disease ■
Preventing myocardial injury in surgery using
cardiopulmonary bypass (human, rat)
P50HL-17669-04 0006 Ischemic heart disease center
(SCOR) - Studies of hypoxic, acidotic and ischemic cardiac
muscle (dogs)
P50HL-17669-04 0012 Ischemic heart disease center
(SCOR) - Circulatory assistance (human, dog)
ROlHL-17719-03 Lung injury, substrate utilization, oxygen
toxicity (rats, rabbits, dogs)
ROltlL-17732-03 Peripheral venomotor control in thermal
stress (human)
ROlHL-17768-04 Development of collateral ventilation
(dogs, fish, horses)
ROlHL-17853-03 Peripheral circulation in heart failure
(animals)
I POlHL-17871-04 Kidney, sodium, cardiac output, arterioles
and hypertension
* POlHL-17871-04 0009 Kidney, sodium, cardiac output,
arterioles and hypertension - Kidney, sodium, cardiac
output, arterioles and hypertension
ROlHL-17903-03 Regional circulatory responses to hypoxia
(rats, cats, rabbits)
ROlHL-17932-04 Blood flow regulation in muscle (cats)
ROlHL-17944-03 Studies in lung preservation (dogs)
ROlHL-17954-03 Narcotics and the circulation (human,
dogs, pigs, monkeys)
ROlHL-17958-04 Circulatory effects of operant
cardiovascular control (baboons)
'* ROlHL-1797004 Vascular effects of inhibitory behavioral
adaptations (dogs)
ROlHL-1808003 Extrinsic control of intestinal
microcirculation (dogs)
ROlHL-18156-02 Hemodynamics in curved arteries
P50HL1831803 0010 Pathogenesis and complications of
hypertension Hemodynamics in mineralocorticoid and low
renin hypertension (human)
P50HL 18323-04 0042 SCOR hypertension center • Blood
viscosity and blood volume in hypertensive disease
(human, dog)
P50HL 18323-04 0046 SCOR hypertension center -
Coronary artery bypass surgery -Associated hypertension
(human)
P50HI- 18323-04 0047 SCOR hypertension center -
Transcendental meditation and self-hypnosis-Hypertension
treatment (human)
** ROlHL-18426-04 Regulation of renal hemodynamics (dogs)
M POlHL-18575-03 Mechanisms of vascular changes in
hypertension
** POlHL-18575-03 0001 Mechanisms of vascular changes
in hypertension - Arteries and resistance vessels in
hypertension (pigs, rats)
POlHL-18575-03 0002 Mechanisms of vascular changes
in hypertension - Endocrines, electrolytes, and
hemodynamics in hypertension (pigs)
** POlHL-18575-03 0006 Mechanisms of vascular changes
in hypertension - Evaluation of arterial compliance in
hypertension (human, pigs)
•* POIHL 18575-03 0011 Mechanisms of vascular changes
in hypertension - Chemistry laboratory core facility
118
R01HL18606-04 Pathogenesis and measurement of
pulmonary edema (human, rabbits, dogs)
ROlHL-18845-04 Regulation of renal circulation and salt
excretion (rats, dogs)
R01HL18866-02 Microvascular flow, volume, and
reactivity (rats, cats)
ROlHL-18875-03 Angiotension, prostaglandins, pressure
and the kidney (rats)
POlHL-18974-03 0001 Experimental neurogenic
hypertension program - Central neural systems regulating
arterial pressure (rabbits)
POlHL-18974-03 0006 Experimental neurogenic
hypertension program - Model of sustained arterial
hypertension (cats)
POlHL-18974-03 0008 Experimental neurogenic
hypertension program - Monoamines and hypertension
(rats)
R01HL18979-02 Mechanisms in local regulation of
coronary flow (rabbits)
' ROlHL-18995-04 Cardiovascular determinants of
catecholamine release (dogs)
' ROlHL-19012-03 Smooth muscle of resistance vessels in
hypertension (rats)
ROlHL-19027-03 Calcium and cyclic AMP in causation of
hypertension (rats)
• ROlHL-19039-03 Circulation studies by one vs two circuit
model (dogs)
ROlHL-19091-02 Sustained Increase in cardiac output
(dogs)
P50HL-191 55-02 0004 Pathophysiology of pulmonary
edema - Physical and chemical effects of multiple
pulmonary emboli (sheep)
P50HL-191 90-02 0008 Pulmonary SCOR -Pathophysiology,
management of IRDS - Hemodynamics and gas exchange-
Determinants of hypotension (human, infant)
ROlHL-19202-03 Adenosine, prostaglandins in relation to
coronary flow (guinea pigs)
ROlHL-192 18-03 Local regulation of coronary flow by
prostaglandins (rabbits)
ROlHL-19225-02 0003 Types and mechanims of
pulmonary hypertension - Cardiopulmonary function in pigs
and rats
POlHL-19242-02 0006 Study of vascular smooth muscle -
The contractile system of vascular smooth muscle (swine,
rats)
ROlHL-19252-02 Vascular connective tissue-Role in
atherosclerosis (rabbits)
ROlHL-19287-03 The antihypertensive function of the
renal medulla (human, rats, rabbits)
ROlHL-19298-03 Pulmonary hemodynamics (dogs, cats)
ROlHL-19451-03 0004 Functional characteristics of the
left heart • Quantitative coronary arteriography (human)
* ROlHL-19677-03 Venous structure and function (dogs)
ROlHL-19680-01 Cardiac correlates of behavioral stress in
animals (dog)
ROlHL-19997-02 Prostaglandin precursors and intestinal
vasculature (cats, rabbits)
ROlHL-20080-02 Surgically induced myocardial edema
(dogs)
ROlHL-20124-02 Coronary risk factors (human)
ROlHL-20201-01 Hypertension and vascular steroid
receptors (rats)
ROlHL-20371-02 Intravascular redistribution of blood
volume (dogs)
'* ROlHL-20399-03 Vascular control in experimental diabetes
mellitus (dog)
ROlHL-20429-03 Study of effects of diabetes reactivity
(miniature pigs, rats)
•* ROlHL-20542-03 Regional hemodynamics in spontaneous
hypertension (rats)
ROlHL-20572-02 0001 Hemodynamic relations to
metabolism in hypertension - Hemodynamic and myocardial
functional studies in the SHR (rat)
** ROlHL-20648-01 Physical factors and coronary flow (dogs)
ROlHL-20690-02 Pulmonary hemodynamics in lung edema
during PEEP (dogs)
** ROlHL-20719-02 Cold induced pulmonary hypertension
(cattle)
** ROlHL-20768-02 Mechanisms of circulatory regulation in
heart failure (guinea pigs)
ROlHL-20782-01 Coronary flow regulation by adenosine
(rats, dogs)
ROlHL-20829-02 Fluid mechanics of heart valve
prostheses (dogs, human)
ROlHL-20895-03 0008 Cineangiographic studies of
cardiovascular system - Intercoronary anastomotic
circulation-Stenosis and occlusion (dogs)
ROlHL-20895-03 0010 Cineangiographic studies of
cardiovascular system - Cortical necrosis and acute renal
failure (human, dogs, rats, rabbits)
ROlHL-20895-03 0011 Cineangiographic studies of
cardiovascular system - Ventricular hypertrophy and
preoutflow contraction (human, dogs)
ROlHL-21030-01 Calcium regulation and hypertension
(rats)
ROlHL-21034-01 Compensatory responses to arterial
occlusion (dogs)
R23HL-21066-02 Angiotensin and prostaglandin control of
aldosterone (rats)
ROlHL-21103-01 Parametric mechanical studies of
hypertensive arteries (dogs, rats)
CAR
ROlHL-21187-01 Potassium, norepinephrine, and coronary
arterial tone (dogs)
ROlHL-2 11 88-02 Pulsatory water flux and endothelial cell
desquamation
ROlHL-21245-02 Influence of chronic exercise on
hypertension (rats, primates)
R23HL-21298-02 Coronary vasomotion (dogs, pigs)
* R23HL-21332-02 Pulsatile regulation of flow in the
microcirculation (cats)
ROlHL-21498-02 Pathophysiology of edema (rats, cats)
* ROlHL-2 1523-01 Hemodynamic effects of dietary sodium
in man
ROlHL-21525-02 Effect of cations, anions and water upon
blood vessels (dogs, rats)
ROlHL-21578-01 Effect of exercise upon the hypertensive
adolescent
ROlHL-21657-01 Regional nonischemic myocardial
hypoxia (dogs)
ROlHL-2 1893-01 Blood volume distribution in hypertension
(human)
R23HL-21943-01 Capillary morphology in pulmonary
edema (dogs)
ROlHL-22005-01 Intermittent retroperfusion of ischemic
myocardium (dogs)
ROlHL-22069-02 Experimental renal arterial hypertension
(dogs)
"* ROlHL-22149-01 Morphologic examination of brain
parenchymal vessels (cats)
** ROlHL-222 16-02 Vascular mechanisms in renal
hypertension (dogs)
ROlHL-22223-01 The cardiopulmonary junction (dogs,
models)
** ROlHL-22244-01 Cardiopulmonary bypass and the
vascular endothelium (dogs)
R23HL-22346-01 Hematological injury and pulmonary
dysfunction (human, mammals)
ROIHL 22546-02 Baroreceptor reflex mechanisms in man
ROlHL-22594-01 Reflex control of the circulation in heart
failure (dogs)
ROlHL-22617-01 Angiotensin, hypertension and the CNS
(sheep)
R23HL-22669-01 Cardiovascular effects from visceral
afferents (dogs)
** R23HL-22728-01 Neural control of renin secretion (dogs)
ROlHL-22801-01 Analysis of coronary artery behavior
(dogs)
ROlHL-22836-01 The spontaneously hypertensive kidney
(rats)
ROlHL-22917-01 Microvascular pressures in the intact
beating heart (rabbits)
R23HL-22972-01 Microcirculatory function in hypotension
(rats, hamsters)
R23HL-22975-01 Dynamics of autoregulation of muscle
blood flow (dogs)
** ROlHL-22977-01 Role of vasoconstrictor mechanisms in
heart failure (human, dogs)
** ROlHL-23171-01 Coronary collateral circulation In
myocardial ischemia (dog. pig. rat. human)
ROlHL-23201-01 Mechanisms of hypertension (human,
rats)
ROlHL-23210-01 Biology of normal and hypertrophied
pulmonary vessels (cat. human)
ROlHL-23211-01 Active normoxic pulmonary vasodilatation
(rat, dog, sheep)
ROlHL-23232-01 Effect of hypoxia on PVSM and its
precursor cells
ROlHL-23239-01 Functional characteristics of pulmonary
vascular smooth muscle (dogs)
** ROlHL-2331201 Hemodynamics and vasoactivity in renal
hypertension (human, dogs)
ROlHL-23600-01 Ions, water, and hypertension (human,
dogs, rats)
ROlHL-23602-01 Physiology of renin, aldosterone and
prostaglandin (human, rats, dogs)
ROlHL-23982-01 Control of coronary flow by carbon
dioxide tension (dogs)
CARDIOVASCULAR FUNCTION, VASOMOTION
SEE ALSO CARDIOVASCULAR AGENTS, VASOACTIVE AGENTS
(GENERAL)
SEE ALSO CARDIOVASCULAR DISORDERS, VASOSPASM
** ROlHL-00487-29 Vasomotor tone and venous return
(human, dogs, monkeys )
ROlHL-01755 25 Fetal and neonatal cardiovascular
function (sheep)
ROlHL-08359-14 Morphopharmacology of vascular
adrenergic transmission (rabbits, rats)
M POlHL-08682-15 Regulation of the cardiovascular system
POlHL-08682 15 0005 Regulation of the cardiovascular
system - Smooth muscle and mechanical properties of
blood vessels (dogs, human)
•* POlHL-10342-13 0024 The integrated function of
respiration and circulation - Cytochrome P450 and
physiological response to hypoxia (rats)
POlHL-10436-13 0014 A multidisciplinary study of
congenital heart disease - Cardiovascular pharmacology
(dog)
ROlHL-10881-13 Structure and function of
microcirculation (hamsters, rats, cats, dogs)
POlHL-12738-10 0042 Physiologic pharmacology and its
clinical applications - Centrogenic cardiac arrhythmias
(cats)
(contd)
•Excludes nxjtine melhodotogy OR covers only general projects which preclude indexing at the specific level.
"Oiiented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigatoi's name and grant number.
v^f jr:a^^>:KXivv«'
CAK
HOINl 13187 09 Cantral naural conliol o( cirdloviiculii
function (cats)
ROIHL 13634 08 Ranal hyparlanslon in piagnancy (sheap)
POIHL 1438807 0166 Rafulatlon of ttie CKculalion in
patholoiical statas Elastic changes in abdominal aoria
with athaiosclarosis (Rhasus monkays)
POIHL 14388 07 0184 Regulation of the circulation in
pathological states Vestibular lelleies in control ol
circulation (human)
POIHL 14388 07 0229
pathological states
(human)
POIHL 1438807 0234
pathological statas
Regulation ol the circulation In
Mechanism of postural hypotension
Regulation of the circulation in
Effects ol antiarrhythmic drugs on the
autonomic system (dogs)
ROIHL 14693 07 Survival value of physiological responses
to hypoxia (dogs)
"* ROIHL 14944 07 Renal vascular reactivity in hypertensive
patient
•* POIHL 15194 07 0018 Pathophysiology of
cardiopulmonary dysfunction Coronary circulation.
metabolic demand and vasodilatory reserve (human, dogs)
ROIHL 1523105 Mechanisms of hemodynamic changes
during digestion (dogs)
ROIHL 1556205 Regulation of skeletal muscle blood flow
(dogs)
ROIHL 1558006 Humoral control of pulmonary and
systemic circulation (animals)
POIHL 1583506 0012 Study of muscles related to heart
disease Contraction and energetics of visceral and
vascular smooth muscles (rabbits)
■* POIHL 1583 506 0019 Study of muscles related to heart
disease Vascular smooth muscle -Electron microscopy.
excitation contraction (animal)
ROIHL 16003-08 Sources and roles of calcium in smooth
muscle excitation (rats)
R01HL-I6094-06 The dynamics of micracirculatory function
(dogs)
POIHL 16117-05 0008 Ion movements and membranes in
cardiovascular control Arterial smooth muscle calcium
fluxes and contractility (rabbits)
* R01HL16315-05 Analysis of interaction between CNS
vasomotor systems (cats, rats)
ROlHL-1632806 Membrane electrical properties of
vascular muscle (human, animals)
f POlHL-16910-05 Regulation of the peripheral circulation
POlHL-16910-05 0001 Regulation of the peripheral
circulation - Quantitative studies of microcirculatory control
(bats)
POlHL-1691005 0006 Regulation of the peripheral
circulation ■ Regulation of blood flow distribution (baboons,
dogs)
ROlHL-17591-03 Development of electromagnetic
rheoangiography (human, dogs)
* P50HL-1764604 0014 Study of ischemic heart disease ■
Progression of ischemic injury in conscious dogs (also
rabbits)
ROlHL-1 7732-03 Peripheral venomotor control in thermal
stress (human)
* POlHL-17813-04 0001 Lung disease and the oxygenation
of blood and tissue - Diffuse interstitial lung disease-
Pathophysiology (human, dogs)
ROlHL-17954-03 Narcotics and the circulation (human.
dogs. pigs, monkeys)
ROlHL-17993-04 0003 Ventricular dynamics from
surgically inserted markers - Effects of pharmacologic
agents on left ventricular dynamics (human)
ROlHL-18516-03 Atherosclerosis and the arterial
contractile proteins (pigs, rabbits)
POlHL-18575-03 0001 Mechanisms of vascular changes
in hypertension - Arteries and resistance vessels in
hypertension (pigs, rats)
POlHL-18575-03 0007 Mechanisms of vascular changes
in hypertension - Microscopy of hypertensive arterial lesions
(rats)
ROlHL-18831-03 Microscopy of spontaneously hypertensive
arterial lesion (rats)
ROlHL-18845-04 Regulation of renal circulation and salt
excretion (rats, dogs)
ROlHL-18866-02 Microvascular flow, volume, and
reactivity (rats, cats)
ROlHL-18873-02 Earfy radiologic diagnosis of cardiac
failure (monkey)
ROIHL 18976-03 Blood pressure control-Relation to
behavioral stress (human, dog)
ROIHL 18979-02 Mechanisms in local regulation of
coronary flow (rabbits)
ROlHL-19134-04 Angiotensin, prostaglandins, adrenergic
interactions (rats, rabbits)
R01HL-I9144-03 Contraceptive steroids and experimental
hypertension (rats)
ROlHL-19218-03 Local regulation of coronary flow by
prostaglandins (rabbits)
ROlHL-19226-03 Vascular smooth muscle in hypertension
(rats)
ROlHL-19298-03 Pulmonary hemodynamics (dogs, cats)
ROlHL-19374-03 Pharmacology of kinins in cardiovascular
disease (rats, rabbits)
R01HL-I9997-02 Prostaglandin precursors and intestinal
vasculature (cats, rabbits)
ROlHL-20163-02 Competitive coronary flow in native and
graft vessels (dog)
119
ROIHL 70206 02 Carbohydritti nucleotides and adrenergic
Interactions (rabbits, cats, rats)
ROIHL 20726 02 Cardiac bypass and coronary collateral
physiology (dogs)
ROIHL 20547 03 Regional hemodynamics In spontaneous
hypertension (rats)
ROIHL 20648 01 Physical (actors and coronary flow (dogs)
ROIHL 20685 02 Pituitary adrenergic ovarian vasomotor
interaction (dogs)
ROIHL 20782 01 Coronary flow regulation by adenosine
(rats, dogs)
ROIHL 20800 17 Neural basis of respiratory and
vasomotor activity (cats)
POIHL 2101602 0013 Sickle cell anemia and other
hemoglobinopathies Microcirculatory response to sickle
cell treated with anti sickling agents (rats)
R23HL 21066 02 Angiotensin and prostaglandin control of
aldosterone (rats)
ROIHL 21 187 01 Potassium, norepinephrine, and coronary
arterial tone (dogs)
ROlHL-2127001 Correlation of arterial hemodynamics and
morphology (human)
R23HL 21298-02 Coronary vasomotion (dogs, pigs)
R23HL 21421 01 Myocardial and vascular contractility and
cyclic nucleotides (cattle, rats)
ROIHL 2152502 Effect of cations, anions and water upon
blood vessels (dogs, rats)
R23HL-21914 01 Studies of vasomotor control (rats)
R01HL-22I49-01 Morphologic examination of brain
parenchymal vessels (cats)
ROIHL 22486-01
cells (swine)
ROlHL-22547-01
Enzyme regulation in cultured arterial
Behavioral treatment of Raynaud's
disease (human)
ROlHL-22573-01 Treatment of post surgical
vasoconstriction (dogs, monkeys, human, rats)
ROlHL-22740-01 Behavior and cardiovascular disease-
Basic mechanisms (human)
ROlHL-22801-01 Analysis of coronary artery behavior
(dogs)
R01HL22873-01 Adrenoceptor interconversion and
hormone homeostasis
R23HL-22975-01 Dynamics of autoregulation of muscle
blood flow (dogs)
** ROlHL-22977-01 Role of vasoconstrictor mechanisms in
heart failure (human, dogs)
ROIHL-23201-01 Mechanisms of hypertension (human
rats)
CARDIOVASCULAR FUNCTION, VASOMOTION,
PULSE PRESSURE WAVES
" ROlHL-00487-29 Vasomotor tone and venous return
(human, dogs, monkeys )
P01HL-04654-I8 0009 Cardiovascular and lung dynamics
- Biological signal and image processing techniques (dogs)
** R01HL-10330-1I Physiological mechanics of the heart and
arteries (dogs, rabbits, horses)
ROlHL-1 1289-12 Analysis of stress in pulsatile dynamics
R01HL-I1919-08 Pulmonary circulation in surgical heart
disease (human, dogs)
** ROiHL-12083-11 Flow field in aorta and its major
branches (dogs, phantom models)
** ROlHL-12607-10 Dynamics of pulsatile blood flow (human,
dogs, rats)
POlHL-13737-07 0013 Assisted circulation - Incorporation
of sensors (human, dogs)
POlHL-13737-07 0034 Assisted circulation - Phasic aortic
flow and cardiac output from phasic pressures (dogs)
** POlHL-13737-07 0035 Assisted circulation - Mapping the
geometry and elasticity of the aorta
POlHL-13737-07 0036 Assisted circulation - Assessment
of infarct size from hemodynamic measurements
" P50HL-1416407 0038 A/S SCOR-Comparative and
experimental atherosclerosis Peripheral vascular studies-
Cholesterol, lesion regression, vascular function
P50HL-14164-07 0042 A/S SCOR-Comparative and
experimental atherosclerosis - Comparative cardiology
laboratory (monkeys)
ROIHL- 156 76-06 The role of occult myocardial failure in
human shock (human, dogs)
ROlHL-16236-04 Detailed characteristics of coronary blood
flow (horses, dogs, calves)
POlHL-17421-05 0004 Regulation and exchange in the
microcirculation - Localization of flow regulation in the
microcirculation (cats, human)
ROlHL-17628-03 Pulsatile pressure-flow dynamics (dogs)
POlHL-18974-03 0008 Experimental neurogenic
hypertension program - Monoamines and hypertension
(rats)
ROlHL-18976-03 Blood pressure control-Relation to
behavioral stress (human, dog)
R01HL-18995-04 Cardiovascular determinants of
catecholamine release (dogs)
ROlHL-19406-03 Grading of atherosclerosis by CW doppler
ultrasound (human, dogs)
** R23HL-21332-02 Pulsatile regulation of flow in the
microcirculation (cats)
ROlHL-221 13-02 Micro/macrovasculature in healing of
foot lesions (human)
ROlHL-221 78-01 Lung airway properties by acoustic
impulse reflection
ROlHL-22223-01 The cardio-pulmonary junction (dogs,
models)
•fadudes rwrtine mettwdokief OR covers only general projects which preclude indexing
^Wented significantly to aliave subject.
at the specific level.
M Grant has subprojects describing specific research aspects
See Appendix lor investigator's name and grant number
CAR
" ROIHI 22604 01 Non Invailv* lyilam for irttrloicKroiii
tludiei (human)
ROIHI 23239 01 funclionil chartcteriilici of pulmonary
vascular smooth mutcia (dogs)
N0IHR6792Q02 Noninvasive diagnoiii of pulmonary
hypertension (dog. human)
CARDIOVASCULAR INFECTIONS
SEE ALSO BLOOD TOXICOLOGY. BACTf RIMIA Sf PIlCfMIA
SEE ALSO HEART DISORDERS. ENDOCAHDIIIS BACTERIAL
SEE ALSO HEART DISORDERS, RHEUMATIC HEART DISEASE
*• POIHL 06314 17 0060 Immunologic mechanums in
cardiovascular disease StrepI antigens and infections in
cardiovascular complications (human, animals)
** ROIHL 18152 03 Vascular injury and atherosclerosis
(mice, coxsackievirus)
CARDIOVASCULAR NEOPLASMS
SEE NEOPLASMS OF CARDIOVASCULAR SYSTEM
CARDIOVASCULAR PHARAAACOLOGY
SEE ALSO CARDIOVASCULAR DISORDERS CHEMOTHERAPY
ROIHL 00487 29 Vasomotor tone and venous return
(human, dogs, monkeys )
R01HL01015-27 Hypertension and left ventricular
hypertrophy (dogs)
ROlHL-01486 23 Quantitative study of T wave mechanisms
(human, rabbits, dogs, chickens)
R01HL01813-25 Regulation ol metabolism by drugs and
hormones (rats)
** ROlHL-0295317 Autonomic and cardiovascular
pharmacology (rats, rabbits, dogs, guinea pigs)
** ROlHL-03181 21 0025 Hemodynamics as applied to
surgical problems Vascular stenosis (dogs)
R01HL03299-21 Dietary effects on cholesterol metabolism
(rats, rabbits)
ROlHL-04457 20 Cellular aspects of active transport (fish.
rabbits, anurans. turtles)
POlHL-04664 18 0010 Cardiovascular and lung dynamics
- Left ventricular dynamics (human)
POlHL-04664-18 0012 Cardiovascular and lung dynamics
- Quantitative single plane left ventricular angiography
(human)
ROlHL-05062 18 Lipid metabolism in cultured cells
(human, rats, rabbits)
ROlHL-05806-18 Analysis of antiarrhythmic agents (dogs,
rabbits)
** ROlHL-05883-18 0001 Reflex control of resistance and
capacitance vessels - Naturally occurring vasoactive
substances and the vascular neuroetfectors (dog)
ROlHL-05883-18 0002 Reflex control of resistance and
capacitance vessels Adenosine, adenine nucleotides and
vascular smooth muscle (dog)
** ROlHL-05883-18 0003 Reflex control of resistance and
capacitance vessels - Cardiac glycosides and sympathetic
nerve terminals in vascular smooth muscle
" ROlHL-05883-18 0004 Reflex control of resistance and
capacitance vessels Lett ventricular receptors with
nonmedullated vagal afferents (cats)
POIHL-06285-18 0125 Cardiovascular-respiratory
physiology and biochemistry - Myocardial function in the
fetal and neonatal lamb
POlHL-06285-18 0126 Cardiovascular-respiratory
physiology and biochemistry Ventricular output, foramen
ovale and ductus arteriosus flows (lambs)
POlHL-06285-18 0130 Cardiovascular-respiratory
physiology and biochemistry - Ductus arteriosus-
Morphological development (human, lambs)
POlHL-06285-18 0132 Cardiovascular-respiratory
physiology and biochemistry - Umbilical-placental
circulatory responses (lambs)
♦• POlHL-06285-18 0135 Cardiovascular-respiratory
physiology and biochemistry - Beta-adrenergic agents and
fetal cardiovascular dynamics (lambs)
POlHL-06285-18 0147 Cardiovascular-respiratory
physiology and biochemistry - Metabolic regulation of
cerebral microcirculation (cats)
** POlHL-06285-18 0153 Cardiovascular-respiratory
physiology and biochemistry - Myocardial mechanics and
pharmacology in isolated papillary muscle (animals)
POlHL-06285-18 0155 Cardiovascular-respiratory
physiology and biochemistry - Therapeutic alterations,
contractile state in heart failure
POlHL-06285-18 0158 Cardiovascular-respiratory
physiology and biochemistry - Load on myocardial
contractility (dogs)
POlHL-06285-18 0182 Cardiovascular-respiratory
physiology and biochemistry - Structure and function of
vascular chemoreceptors (cats, rats)
POlHL-06285-18 0186 Cardiovascular-respiratory
physiology and biochemistry - Leukocyte hormone receptors
and cyclic nucleotides (tissue culture)
M POlHL-06296-18 Cardiovascular and pulmonary
adaptation to stress
** POlHL-06296-18 0005 Cardiovascular and pulmonary
adaptation to stress - Regulation of ventricular
performance (animals)
POlHL-06296-18 0007 Cardiovascular and pulmonary
adaptation to stress - Cardiovascular control during
isometric exercise (cats)
POlHL-06308-18 0025 Mechanisms and therapy of
circulatory disease - Subcellular calcium pools in the
genesis of arrhythmias (dogs)
(contd)
CAR
POlHL-06308-18 0039 Mechanisms and therapy of
circulatotv disease - ANS in regulation of electrophysiology--
Role of cyclic nulceotides (animals)
R01HL-G6736-18 Biogenic-mechanical factors in
microcirculation (rats, gerbils)
ROlHL-07776-15 Sudden death and cardiac arrhythmias
(human, dogs, cats)
ROlHL-08508-15 Cardiac conductivity and automaticity
(human, dogs, rabbits)
** ROlHL-08570-15 Pharmacologic and reflex influence on
vascular tone (dogs, rabbits)
P01HL0868215 0021 Regulation of the cardiovascular
system - Hypoglycemia in pathogenesis of shock (dog)
POlHL-08682-15 0022 Regulation of the cardiovascular
system - Blood pressure responses and preganglionic
sympathetic outflow (cat)
POlHL-0868215 0026 Regulation of the cardiovascular
system - Hypertension-High renin vs low renin (dog)
R01HL09154-14 Central control of distribution of organ
blood flow (monkeys)
** ROlHL-09283-14 Pharmacology of molluscan hearts (also
rabbits)
ROlHL-1001811 Effect of aging on beating heart cells in
culture (rats)
P01HL10436-13 0001 A multidisciplinary study of
congenital heart disease - Assessment of the outlook for
children with congenital heart disease
POlHL-1043643 0002 A multidisciplinary study of
congenital heart disease - ti/lyocardial performance,
metabolism and ultrastructure (human, cats, rats)
** POlHL-1043613 0014 A multidisciplinary study of
congenital heart disease - Cardiovascular pharmacology
(dog)
POlHL-10436-13 0015 A multidisciplmary study of
congenital heart disease - Fetal and neonatal
cardiovascular physiology (sheep)
P01HL10539-12 0068 Pathophysiology of circulation ■
Acute and chronic cardiomyopathies (mice, dogs, hamsters,
human)
ROlHL-10881-13 Structure and function of
microcirculation (hamsters, rats, cats, dogs)
ROlHL-1089712 Effects of hormones on cardiac
electrogenesis (rabbits, guinea pigs, dogs)
ROlHL-10942-09 Study of genetic hypertension in rats
M P01HH1310-12 Mechanisms of cardiovascular disease
P01HL11310-12 0062 Mechanisms of cardiovascular
disease - Myocardial depressant factor in postoperative
cardiac dysfunction (human, dogs)
P01HL11310-12 0063 Mechanisms of cardiovascular
disease - Myocardial function, metabolism and cellular
integrity after heart surgery (dogs)
** P01HL11310-12 0068 Mechanisms of cardiovascular
disease - Pharmacological intervention and myocarcial
oxygen consuption (human, dogs)
POlHL-1131012 0078 Mechanisms of cardiovascular
disease - Ventricular arrhythmias in acute myocardial
infarction (dogs)
** POlHL-11310-12 0079 Mechanisms of cardiovascular
disease • Electrophysiological studies of complete heart
block (human)
POIHL 11310-12 0081 Mechanisms of cardiovascular
disease - Analysis of regional left ventricular function
(human)
** POlHL-11310-12 0087 Mechanisms of cardiovascular
disease - Electrophysiology and electropharmacology of the
heart (dogs)
POlHL-1 1310-12 0092 Mechanisms of cardiovascular
disease - Exercise electrophysiology (human)
POlHL-11310-12 0102 Mechanisms of cardiovascular
disease - Cardiac membrane and ion mobility (dogs)
POlHL-1 1351-12 0001 Cellular and molecular
mechanisms of myocardial function - Ionic control of
myocardial contractility (animals)
POlHL-1135112 0010 Cellular and molecular
mechanisms of myocardial function ■ Basic ionic exchange
studies (rats)
P01HL11351-12 0015 Cellular and molecular
mechanisms of myocardial function - Effects of hypoxia
and ischemia on ion exchange and heart function (rabbits)
R01HL-n80210 Cardiovascular surgical research (dogs,
sheep, swine, cats, monkeys)
ROIHL 11907-08 Mechanisms of physiological responses
to exercise (human, dogs)
ROlHL-12085-10 Lipoprotein-carbohydrate metabolism
(human, rats)
** ROIHL 1232210 Extrinsic factors influencing myocardial
performance (dogs, swine)
M P01HLI2373-10 Cardiopulmonary physiology and
pathophysiology
POlHL-12373-10 0005 Cardiopulmonary physiology and
pathophysiology - Characterization of fetal and neonatal
myocardium (human, cats)
POlHL-12373-10 0012 Cardiopulmonary physiology and
pathophysiology - Biochemistry of the sympathetic nervous
system (rats, rabbits, pigeons)
•* POlHL-12373-10 0013 Cardiopulmonary physiology and
pathophysiology - Effects of cardiovascular drugs on left
ventricular function (dogs)
ROlHL-12421-10 Pathophysiology of circulatory shock
(dogs, baboons)
R01HL12647-08 Inactivation of norepinephrine in vascular
tissue
120
ROlHL-12677-10 Surgical physiologic studies of isolated
kidneys (dogs, rats)
R01HL12684-09 Angiotensin I and converting enzyme in
hypertension (human, primates, dogs)
VI POlHL-12738-10 Physiologic pharmacology and its clinical
applications
** POlHL-12738-10 0001 Physiologic pharmacology and its
clinical applications - Clinical pharmacology of cardioactive
drugs (human)
** POlHL-1273810 0035 Physiologic pharmacology and its
clinical applications • Function and dysfunction of the
sinoatrial node (human)
** POlHL-12738-10 0044 Physiologic pharmacology and Its
clinical applications - Cardioactive drugs and
electrophysiological properties of cardiac cells (sheep)
** POlHL-12738-10 0080 Physiologic pharmacology and its
clinical applications ■ Electrophysiology of cardiac muscle
in the mitral valve (monkeys)
** P01HL12738-10 0109 Physiologic pharmacology and its
clinical applications - Effects of calcium blockers on
skeletal and cardiac muscle (cats)
** POlHL-12738-10 0110 Physiologic pharmacology and its
clinical applications - Physiology and pharmacology of
arrhythmias (dogs)
** POlHL-12738-10 0111 Physiologic pharmacology and its
clinical applications ■ Cardiovascular pharmacology (dogs)
** POlHL-12738-10 0132 Physiologic pharmacology and its
clinical applications ■ Coronary occlusions and arrhythmias
(dogs)
** P01HL12738 10 0133 Physiologic pharmacology and its
clinical applications ■ Pharmacologic antagonism of beta-
adrenergic blockade (dogs)
ROlHL-12777-09 Mechanisms in cardiac performance
(dogs, human)
M POlHL-13 108-09 Clinical heart transplantation
** POlHL-13108-09 0008 Clinical heart transplantation ■
Physiology and pharmacology of the transplanted human
heart
** POlHL-13108-09 0017 Clinical heart transplantation ■
Electrophysiology of the transplanted denervated human
heart
** POlHL-1310809 0018 Clinical heart transplantation -
Electrophysiologic studies of cardiac drugs in the
denervated heart
R01HL13187-09 Central neural control of cardiovascular
function (cats)
R01HL1325709 Inhalation anesthesia on myocardial
metabolism (dogs, swine, human)
** ROlHL-13306-08 Pharmacological control of cardiac
membrane currents (cattle, rabbits)
** ROlHL-13339-08 Pharmacology of developing cardiac
tissues (chick embryo)
R01HL13349-06 Analysis of activation process in heart
muscle (guinea pigs, rabbits, human)
** ROlHL-13636-08 Effects of pharmacologic agents on heart
metabolism (human, rodents)
R01HL13666-06 Pharmacology of genesis of cardiac
rhythmicity (rats, cats)
R01HL13722-08 Acid and alkaline lipases in aortas (rats,
rabbits, human)
POlHL-1373808 0002 Cardiac assist devices and
artificial hearts ■ Total replacement with artificial heart
(calves, sheep, ponies)
R01HL13870-09 Control of myocardial sarcotubular
calcium stores (dogs)
R01HL1393606 t^icrovascular responses in hypertension
(human, rats)
R01HL14127-16 Methemoglobinemia and antihypertensive
drugs (cats, mice, rats)
P50HL14147-08 0012 Specialized center of research in
thrombosis - Tissue culture study of arterial cells (human,
hamster)
*♦ P50HL-141 59-08 0020 Specialized center of research in
hypertension - Renin-mineralocorticoid system in
hypertension (human, rat, dog)
M P50HL-14187-07 Pulmonary SCOR -Chemical mediators in
pulmonary vascular responses
P50HL141 87-07 0012 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses - Vasoactive
mediators in pulmonary disease (human, animal)
P50HL-14187-07 0014 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses ■ Metabolism
and actions of vasoactive peptides in lung (human,
mammals)
** P50HL-14187-07 0015 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses ■
Pathophysiologic responses of pulmonary capillary bed
(dog, human)
M P50HL14192-08 Specialized center of research in
hypertension
** P50HL14192-08 0003 Specialized center of research in
hypertension • Prostaglandins as mediators of renin
secretion (human, dog)
** P50HL141 92-08 0005 Specialized center of research in
hypertension • New techniques for recognition of
renovascular hypertension (human, dogs)
P50HL-14192-08 0007 Specialized center of research in
hypertension - Role of new mincralocorticoids in
hypertension (human, rats)
P50HL-142 17-08 0049 Specialized center of research in
thrombosis • Fibrinolysis section -Clinical studies
CAR
P50HL-14217-08 0051 Specialized center of research in
thrombosis - Microcirculation section (bat, hamster)
P50HL-1421708 0054 Specialized center of research in
thrombosis - Coagulation section -Platelet aggregation
(human, pig, rabbit, dog)
" P50HL-14217-08 0061 Specialized center of research in
thrombosis - Pharmacology -Comparison of platelets and
vascular smooth muscle (animal)
P50HL-14218-07 0017 Pulmonary SCOR -Newborn lung
center - Transvascular fluid exchange, vasoactive mediators
in RDS (sheep, cat)
M POlHL-14388-07 Regulation of the circulation in
pathological states
P01HL14388-07 0219 Regulation of the circulation in
pathological states - Myocardial ischemia and infarction in
animals (dogs)
** POlHL-14388-07 0220 Regulation of the circulation in
pathological states - Pharmacology of the coronary
circulation in man
ROlHL-14397-07 Hypertension-Angiotensin and
prostaglandin pharmacology (animals)
R01HL14509-07 Hypertension-Chemistry and biophysics
of angiotensin
R01HL14545-06 Mechanics of compensatory ventricular
hypertrophy (dogs)
ROlHL-1457105 Myocardial preservation and coronary
repertusion (baboons, dogs)
R01HL14614-07 Voltage control of contraction in heart
(sheep)
R01HL14693-07 Survival value of physiological responses
to hypoxia (dogs)
** R01HL14706-07 Fetal hearts in organ culture (mice)
ROlHL-1471306 Hypothermia and the heart (bats, guinea
pigs)
** ROlHL-14775-08 Mechanisms of drug action in vascular
smooth muscle (dog, rabbits)
** ROlHL-1483206 Myocardial cells-Autonomic and rhythmic
mechanisms (chick embryo, rats)
R01HL14899-07 Mechanism and prevention of cardiac
arrhythmias (dogs)
ROlHL-1494407 Renal vascular reactivity in hypertensive
patient
ROlHL-15047-06 Digital computer analysis of the
electrocardiogram (human)
•* P60HL- 15 160-07 0016 Center for sickle cell disease -
Kinin and plasmin system in sickle cell disease (human)
** P01HL1519407 0004 Pathophysiology of
cardiopulmonary dysfunction • Specialized electrophysiology
fibers -Electrogenic basis of glycosides (mammals)
POlHL-15194-07 0019 Pathophysiology of
cardiopulmonary dysfunction ■ Coronary circulation, bypass
grafts and diastolic driving pressure (human, dogs)
ROlHL-15247-05 Extending the life of implanted
pacemakers (dogs, human)
ROlHL-15270-06 Local mechanical properties of the aortic
tissue (dogs, pigs)
ROlHL-15308-07 Assays for peptides of lipoproteins
(human)
** ROIHL- 15444-06 Neonatal development of adrenergic
receptor mechanisms (pigs)
ROlHL-15498-06 Effects of physical training on heart
(rats)
R01HL-15522-06 Influence of mannitol on ischemia
cardiac muscle (dogs, cats, rats)
R01HL15580-06 Humoral control of pulmonary and
systemic circulation (animals)
ROlHL-1560706 Physiological control of splanchnic
circulation (dogs)
ROlHL-15676-06 The role of occult myocardial failure in
human shock (human, dogs)
ROlHL-15681-06 Coronary flow studies of partially
obstructed vessels (dogs)
ROlHL-15696-06 Mechanism and role of cyclic GMP in
heart (animals)
ROlHL-15740-06 In vrtro studies on heart cell function
(rats)
" ROlHL-15758-06 Catecholamine release in the heart
(dogs)
POlHL-15835-06 0025 Study of muscles related to heart
disease - Cellular biology of vascular smooth muscle
(guinea pig)
R01HL15837-06 Renin and cardiac hypertrophy in
hypertension (rats)
ROlHL-15930-06 Hormonal control of lipid and lipoprotein
^ synthesis (rats)
ROlHL-15965-06 Experimental atherosclerosis and elastin
metabolism (chicks)
ROlHL-1598304 Regional myocardial blood flow (dogs)
R01HL15985-06 Metabolic and hormonal control of
cardiac contraction
** R01HL15991-05 Evaluation of heart stimulants in sea
anemones
ROlHL-16037-06 Molecular properties of cardiac
adrenergic receptors
** R01HL16052-05 Cardiac glycosides-Mechanism of
inotropic action (dogs)
ROlHL-16066-05 Studies on neurogenic control of the
circulation (human, dogs)
ROlHL-16076-06 Electrophysiology of fibrillation and
defibrillation (human)
*♦ ROlHL-16094-06 The dynamics of microcirculatory function
(dogs)
(contd)
"Excludes routine methodotogy OR covers only general projects which preclude
"Onented significantly to above subiect.
indexing at the specific level.
M Grant has subproiects describing specific research aspects.
See Appendix for investigator's name and grant number.
CAR
POIHl'l6n70S Ion movtmtnts and nitmbdnis In
cardiovajculat contiol
POIHI 161 W OS 0005 Ion movtmenis and membtanes in
cardiovasculai control Proptrtits of isolalod call
membianes (labbits. cats)
POIHL 161 H Ob 0006 Ion mowaments and membianes in
caidiovasculai contiol Neuioiaceptors and cellulai
excitation dish)
POIHL 16117 Ob 000/ Ion movements and membianes in
caidiovasculai control Physiological and moleculai
properties ol lonophores (dogs, rabbits)
ROIHI 1613b Ob Mechanisms ol cardiac autorhythmiclty
(dogs, bats)
ROIHI I61b206 Electfophysiology ot neonatal to adult
heart (cats, trogs. guinea pigs)
ROIHL 16236 04 Detailed characteristics ol coronary blood
(low (horses, dogs, calves)
ROIHL 16240 05 The cardiac histamine receptor (rabbits.
guinea pigs)
Surgery and non-obstructive
Etiects of exercise on (low
Surgery and non obstructive
Cardiopulmonary resuscitation
Biochemistry and pharmacology of NaK
Role of calcium and thyroxine in heart
Drug treatment ol atherosclerosis
Fluorocarbon emulsions as artificial
Lett ventricular function in exercise
' ROIHL 16292 Ob 0010
coronary insufficiency
distribution (dogs)
' ROIHL 1629205 0017
coronary insufficiency
(human)
ROIHL 16318-21
transport
ROIHL 1643604
function (rats)
ROIHL 1643705
(rabbits, monkeys)
' ROlHL-16474-05 Antibiotic-ion interactions (model
membranes)
ROlHL-16511-04 Sympathetic afferent activity of cardiac
origin (dogs, monkeys)
ROIHL 16549-04 Cardiotonic steroid-NaK ATPase
interactions (cattle)
ROIHL 16588-05 Collagen synthesis in atherosclerosis
(dogs. rats, rabbits, human)
P01HL-16607-05 Calcium ion and control of
cardiovascular function
PO1HL-16607-O5 0003 Calcium ion and control of
cardiovascular function - Calcium transport in
sarcoplasmic membranes (animals)
ROlHL-16611-04 Digitalis-receptor of the heart (guinea
pigs, rats)
ROlHL-16643-02
blood (animals)
ROlHL-16656-06
(dogs)
ROIHL-16678-03 Fluorescent probe studies of heart
muscle proteins (rabbit, dog)
R01HL-16710-03 Myocardial subcellular localization of
calcium (dogs)
ROlHL-16714-05 Endothelial cell communication in
homeostasis (human, mammals)
ROlHL-16760-05 Dynamic control of coronary blood flow
(dogs)
POlHL-16910-05 0002 Regulation of the peripheral
circulation - Coronary circulation (dogs)
P60HL-17269-04 0017 National heart and blood vessel
research and demonstration center - Cell membrane (dogs,
rabbits)
P60HL-1 7269-04 0018 National heart and blood vessel
research and demonstration center • Mitochondria and
energetics (rabbits, dogs)
P60HL-17269-04 0022 National heart and blood vessel
research and demonstration center - Medicinal chemistry
(rabbit, dog. guinea pig)
P60HL-17269-04 0023 National heart and blood vessel
research and demonstration center - Cardiovascular
pharmacology -Ischemia, shock and heart failure (dog. cat.
rat)
P60HL-17269-G4 0024 National heart and blood vessel
research and demonstration center Section of
experimental cardiovascular surgery -Core facility
ROlHL-17341-03 Practical total synthesis of
prostaglandins
ROlHL-17401-03 Mechanisms in angiotensin induced
hypertension (cats, dogs)
ROlHL-17403-03 Metabolic control of cardiac output
(dogs)
ROIHL 17451-05
mechanisms
ROlHL-1 7459-03
ROIHL 1748704
Digitalis effects on cardiac automaticity
Myocardial ischemia (dogs)
Adrenergic-vasoregulation interactions in
hypertension (human)
ROlHL-17516-04 Role of androgen as a risk factor in
atherogenesis (human, animals)
ROlHL-1 7555-05 Distribution and metabolism of labeled
digitaloids (dogs, guinea pigs)
ROlHL-17591-03 Development of electromagnetic
rheoangiography (human, dogs)
R01HL17629-03 Developmental aspects of cardiovascular
function (human, cats, rabbits)
ROIHL 1763105 Experimental congestive heart failure and
hypertrophy (cats)
P50HL- 17646-04 Study of ischemic heart disease
P50HL- 17646-04 0005 Study of Ischemic heart disease -
Biochemical markers and mediators of myocardial ischemic
injury
121
PbOHt 17646 04 0009 Study ol Ischemic heart disease
Regionnl melabulic deran|«m«nts indicating ischemia
(rabbit, dog. human)
PbOHl 1/646 04 0010 Study ol ischemic heart disease
Compliance in iM,h(>init myocardium Altered cardiac
performance (human, dogs)
PbOHl 1/646 04 001? Study of ischemic heart disease
Role ol miciociiculation in progression of myocardial
ischemic injury (rat)
P50HL 1/646 04 0013 Study ol ischemic heart disease
Maintenance of myocardial vascular integrity after
revascularization (dogs)
' PSOHL 17646 04 0014 Study of Ischemic heart disease
Progression ot ischemic Injury in conscious dogs (also
rabbits)
' P50HL 17646 04 0016 Study of ischemic heart disease
Humoral factors in ischemic heart rhythm, mechanical
performance (dog. rabbit)
' P50HL 17646 04 0017 Study ot ischemic heart disease
Dysrhythmia associated with acute myocardial infarction
(human, cat)
P50HL 17648 04 0014 Study of ischemic heart disease
Antidysrhythmic drugs and mammalian cardiac Purkinje
fibers (sheep, dog)
' P50HL 17648 04 0023 Study of ischemic heart disease ■
Chemical mediators of inflammation in acute myocardial
infarction (mammals)
PbOHL 17651 04 Ischemic heart disease specialized center
of research
' P50HL 17651 04 0002 Ischemic heart disease specialized
center ot research Reduction of myocardial ishemic injury
by pharmacologic agents (human, dog)
■ P50HL 17651-04 0022 Ischemic heart disease specialized
center of research - Electrophysiology- Mechanism and
pharmacology of arrhythmias (human, dog)
' P50HL-17651-04 0045 Ischemic heart disease specialized
center ot research Peripheral vascular studies-
Pharmacology (dogs, human)
P50HL-17665-04 0008 Study ot ischemic heart disease -
Core laboratory-CPK isoenzyme measurement and
myocardial necrosis evaluation
P50HL-17665-04 0012 Study of ischemic heart disease -
Myocardial ischemia -Cardiovascular performance in the
conscious baboon and dog
P50HL-17665-04 0021 Study ot ischemic heart disease -
Identification, prevention-Myocardial ischemia in
cardiopulmonary bypass (dog)
' P50HL-I7667-04 0031 Study of ischemic heart disease -
Pathophysiology in ischemic heart disease (dog, cat, rabbit,
monkey)
P50HL-17669-04 0007 Ischemic heart disease center
(SCOR) - Relationship between myocardial depression and
compliance (dogs, cats)
P50HL-1766904 0008 Ischemic heart disease center
(SCOR) - Segmental ventricular dysfunction during stress-
induced ischemia (dog, human)
P50HL17669-04 0011 Ischemic heart disease center
(SCOR) - Lysosomal function and lysosomal enzymes in
normal and ischemic heart (rabbit)
P50HL- 176 70-04 0009 Study ot ischemic heart disease -
Surgical treatment of localized left ventricular dyssynergy
(human, dogs)
P50HL-1767004 0011 Study ot ischemic heart disease ■
Pharmacology ot ischemic myocardium (dogs)
P50HL-17682-04 0005 Study ot ischemic heart disease -
Regional myocardial perfusion deficits and segmental
contraction disorders in man
P50HL-17682-04 0015 Study ot ischemic heart disease -
Acute myocardial ischemia and infarction and their
reversibility (dogs, baboons)
P50HL 17682-04 0020 Study of ischemic heart disease ■
Nucleotide and nucleoside metabolism in ischemic
myocardium
P50HL-1768204 0021 Study ot ischemic heart disease -
Prostaglandin biosynthesis in blood vessels from ischemic
myocardium (rat, sheep)
ROlHL-17729-04 Stimulus-response coupling in platelets
(human)
ROlHL-17736-04 Metabolic change during cardiac
ischemia (rats, dogs)
ROlHL-17747-04 Endothelial injury and regeneration (rats)
ROlHL-1775903 Studies of myocardial reactive hyperemia
(dogs, human)
ROlHL-17796-04 Importance ot aminosugars in digitalis
activity (cats, rabbits)
ROlHL-17882-04 Regulation ot HMG-COA reductase and
sterol synthesis (human, mammals)
ROlHL-17954-03 Narcotics and the circulation (human,
dogs, pigs, monkeys)
ROlHL-17958-04 Circulatory effects of operant
cardiovascular control (baboons)
ROlHL-1797618 Chemical agents and heart glycolytic
enzymes (sheep)
R01HL-17993-04 0003 Ventricular dynamics from
surgically inserted markers - Effects of pharmacologic
agents on left ventricular dynamics (human)
ROlHL-17993-04 0007 Ventricular dynamics from
surgically inserted markers - Digitalis after coronary artery
surgery (human)
ROIHL 18003-05 Digitalis -Mechanism and reversal studies
(dog, sheep, duck, guinea pig. human)
CAR
' ROIHI 18004 02 Transport through arletitl wall
Hiophysitil atpecit (ribbili)
' ROIHI lHOr>0) Pharmacologic iludiet on vatcular
Miiuulli inmrle (dog\, taU)
ROIHI 1801904 (he endocrine kidney in hypartaniion
(mice)
' ROIHI 18024 03 Regional myocardial flow and (unction
relatiunships (dogs)
ROIHI 18080 03 Extrinsic control ol intettinil
miciociiculation (dogs)
ROIHL 18096 04 Vasoactive agents in splanchnic vitc«ra
(primates, dogs)
ROIHI 18190 03 Myocardial blood flow in acute
myocardial inlarction (human, dog^)
ROIHL 18245 03 Transition slate analog inhibitors of
thrombin (human, cattle)
ROIHI 18272 03 Heart adenyl cyclase complex (beef
heart)
' ROIHL 18288 04 Intraoperative protection of the
myocardium (dogs, rats)
' P50HL 18318 03 0014 Pathogenesis and complications of
hypertension Arterial metabolism and atherogenesis (rat,
rabbit)
PbOHL 1831803 001b Pathogenesis and complications of
hypertension Cultured smooth muscle cells and
microvessel metabolism (mammals)
PbOHL 18318 03 0019 Pathogenesis and complications ot
hypertension Renin angiotensin system in blood pressure
regulation (human, rat, dog)
P50HL- 18323 04 0037 SCOR hypertension center
Adrenocortical factors in childhood hypertension
P50HL 18323 04 0043 SCOR hypertension center
Pharmacology Renin aldosterone mechanisms in essential
hypertension (human)
PbOHL 18323 04 0044 SCOR hypertension center
Angiotensin blockade to identify angiotensin II factor in
hypertension (human)
ROIHL 18467-03 Fingertip blood flow in normals and
Raynaud's disease (human)
ROlHL-18468-03 The distribution of flow in the
myocardium (dog, pig)
R01HL18517-03 Intrinsic innervation ot the heart (dogs)
ROlHL-18554-03 Taurine metabolism in mammalian heart
(rodents, cattle, swine)
POlHL-18575-03 0001 Mechanisms of vascular changes
in hypertension - Arteries and resistance vessels in
hypertension (pigs, rats)
POlHL-18575-03 0002 Mechanisms of vascular changes
in hypertension - Endocrines, electrolytes, and
hemodynamics in hypertension (pigs)
ROlHL-18598-03 Role of Na, KATPase inhibition on
digitalis action
ROlHL-18599-02 Cardiovascular pharmacology of
ionophores (dogs)
ROlHL-18624-03 Study of kinins in hypertension and other
diseases (human)
POlHL-18645-03 0006 Biology ot the artery wall and
atherosclerosis - The platelet and atherosclerosis (monkeys,
baboons)
ROlHL-18647-03 Ischemic myocardial injury in cultured
heart cells (rats)
ROlHL-18657-03 Pharmacologic studies on neurogenic
digitalis effects (human, cats, dogs)
ROlHL-18682-03 Protein kinase and cholesterol
metabolism in aorta (rabbits)
ROlHL-18711-03
chicks)
ROlHL-18749-03
Electrophysiology ot heart cells (rats.
Ventricular mechanics in the overloaded
'Excludes routine methodotogy OR covers only general projects which preclude Indexing at the specific level
"Ooenled sienificantly to above subject
M Grant has subprojecis descnbmg specific research aspects.
See Appendix for investigator's name and grant number.
heart (dogs)
ROlHL-18795-04 Ischemic arrhythmias-Effect of
autonomic tone (dogs, rats, guinea pigs)
ROlHL-18796-04 Experimental cardiac arrhythmias (dogs)
ROIHL 18824-03 Mechanisms of heart failure in
myopathic hamster
POlHL-18827-02 0005 Platelet vessel wall interactions in
thrombogenesis - Platelet vessel wall interactions in
thrombogenesis (human)
P50HL-18828-03 0002 Specialized center of research in
thrombosis - Endothelial cell biology (human, guinea pig)
ROlHL-18831-03 Microscopy ot spontaneously hypertensive
arterial lesion (rats)
ROlHL-18866-02 Microvascular flow, volume, and
reactivity (rats, cats)
ROlHL-18887-03 Hypolipidemic drugs-Effects on FFA-
albumin association (human, cattle)
ROlHL-18932-03 Brain microcirculation observed in vivo
after trauma (mice)
R01HL1894303 Contractile activity ot single cardiac cells
ROlHL-18948-03 Pulseless flow and circulatory assistance
(dogs, calves)
ROlHL-18994-03 Substance P-Occurrence, pharmacology
and physiology (mammals non-human, human)
ROlHL-19000-03 Irreversible myocardial injury (rats)
ROlHL-19030-03 Tissue protection during circulatory
interruption (dogs)
ROlHL-19039-03 Circulation studies by one vs two circuit
model (dogs)
ROlHL-1904403 Effect ot drugs on development ot
cardiac failure (cats)
ROlHL-19057-03 Catecholamines and cyclic AMP in
cardiovascular system (rats, dogs)
(contd)
CAR
ROlHL-19066-03 Synthesis and evaluation of
prostaglandin metabolites (guinea pigs)
R01HL19076-03 Vagal control of heart rate-A biophysical
model (rabbits)
ROlHL-19089-03 Diastolic properties of the left ventricle
(human, dogs)
ROlHL-19129-04 Cardiac glycosides-Mechanisms of
cellular actions
P50HL-1915302 0001 SCOR-Pulmonary edemas-Eitology,
pathogenesis • Prostaglandins and the lung circulation
(sheep)
P50HL-1915302 0002 SCOR-Pulmonary ederaas-Eitology,
pathogenesis Lung fluid dynamics -Classical mediators
and their inhibitors (sheep)
** P50HL-19153-02 0003 SCOR-Pulmonary edemas-Eitology.
pathogenesis - Possible inhibitors of mediator release and
pulmonary vascular response (sheep)
R01HL19181-02 Regulation of heart cAMPdependent
protein kinase (rodents)
ROlHL-1920203 Adenosine, prostaglandins in relation to
coronary flow (guinea pigs)
ROlHL-1921603 Characterization of cardiac pacemaker
activity (cat, dog, rabbit)
R01HL19223-03 Control of cholesterogenesis In leukocytes
and liver (rats, human)
POlHL-19259-03 0004 Digoxin-specific antibody in human
therapy ■ Digitalis-specific antibodies pharmacological
studies (human, dogs, sheep)
** ROlHL-19275-03 Characterization of collateral blood
vessels (dogs)
ROlHL-19287-03 The antihypertensive function of the
renal medulla (human, rats, rabbits)
** ROlHL-19298-03 Pulmonary hemodynamics (dogs, cats)
ROlHL-19370-03 Coronary capillary exchange-The effects
of ischemia (dogs, sheep)
** ROlHL-19374-03 Pharmacology of kinins in cardiovascular
disease (rats, rabbits)
ROlHL-19378-03 Relation of mitochondrial changes to
cardiac failure (dogs, rats)
** ROlHL-19394-03 Biochemistry and regulation of taurine in
the heart (rats, guinea pigs, cats)
ROlHL-19398-03 Regional conduction abnormalities and
arrhythmias (dogs)
** ROlHL-19399-02 Atherosclerosis-Early events and
regression factors (rats)
R01HL-194U-03 Protection of myocardium during cardiac
surgery (dogs, cats, human)
ROlHL-19428-03 Role of angiotensin sensitivity in renin
release (human) , ^ , u
M ROlHL-19451-03 Functional characteristics of the left
•i^art . ^. , ,.
ROlHL-19451-03 0001 Functional characteristics of the
left heart - Ventricular pertormance using epicardial
radiopaque markers (human)
ROIHL 19451-03 0003 Functional characteristics of the
left heart - Left ventricular segmental contraction (human,
dogs)
ROlHL-1948703 Cardiac actions of digitalis (dogs, cats)
ROlHL-1953903 Pathology of hypertensive-associated
arteritis (rabbits) .
** ROlHL-19782-02 Pharmacologic studies on the ischemic
heart (dogs) , „ . .
" ROlHL-19820-02 The chemistry and biological effects ot
heparin (Rhesus, human, other mammals)
R01HL19898-03 Desferrioxamine therapy in thalassemia
(dogs, rats, children)
ROlHL-19961-03 Management of hemosiderosis in
thalassemia (children, adults)
ROlHL-19974-02 Psychologic-behavioral influences on
heart pathology (rats)
** ROlHL-2015302 Intracellular pH and myocardial
electropharmacology (dogs, guinea pigs)
ROlHL-2019002 Pathogenesis of cardiac hypertrophy
(dogs) . .
** ROlHL-20199-02 Drug induced alterations in infarct size
in the rat
ROlHL-20226-02 Cardiac bypass and coronary collateral
physiology (dogs)
ROlHL-20230-02 Analysis of the action potential ol
cardiac muscle (sheep)
ROlHL-20262-02 Cardiac glycosides and the mechanism
of the sodium-potassium pump
ROlHL-20283-02 Maintenance of cellular integrity in
ischemic hearts (cats)
•* ROlHL-20369-03 The effect of alcohol on the heart (rats)
ROlHL-20371-02 Intravascular redistribution of blood
volume (dogs)
** ROIHL 20399-03 Vascular control in experimental diabetes
mellitus (dog)
ROIHL 20401-03 Relationship of insulin to catechol
cardiomyopathy (rabbit, pig)
ROlHL-2042603 Myocardial function in diabetes mellitus
(dog, rat)
•* ROlHL-20429-03 Study of effects of diabetes reactivity
(miniature pigs, rats)
** ROlHL-20439-02 Effects of insulin on neurovascular
transmission (human, rats, rabbits, hamsters)
*• ROlHL-20476-03 Effects of diabetes on cardiac
pertormance (rat)
R01HL-20S58-02 Cardiac electrophysiology-Effects of ions
and drugs
122
ROlHL-20563-02 Restoring microcirculation after platelet
aggregation
ROlHL-20572-02 0001 Hemodynamic relations to
metabolism in hypertension - Hemodynamic and myocardial
functional studies in the SHR (rat)
ROlHL-20572-02 0008 Hemodynamic relations to
metabolism in hypertension ■ Role of nervous system m
hemodynamic function
M POlHL-20581-01 Vascular neuroeffector mechanisms in
health and disease
** POlHL-20581-01 0001 Vascular neuroeffector
mechanisms in health and disease - Vascular neuroeffector
mechanism (rabbits)
** POlHL-20581-01 0003 Vascular neuroeffector
mechanisms in health and disease - Cerebrovascular
neuroeffector characteristics (animals)
** POlHL-20581-01 0004 Vascular neuroeffector
mechanisms in health and disease - Neuroeffector
characteristics of mesenteric and pulmonary blood vessels
(rabbits)
** ROlHL-20604-03 Sympathectomy -Cardiovascular and
molecular pharmacology (animals)
ROlHL-206 30-03 Development of a pulsed Doppler velocity
detector (human, animals)
ROlHL-20643-02 Analysis of heart cell contraction (rats)
** ROlHL-20685-02 Pituitary adrenergic-ovarian vasomotor
interaction (dogs)
ROlHL-207 54-02 Anesthetic-induced myocardial depression
(rabbits)
ROlHL-20895-03 0002 Cineangiographic studies ot
cardiovascular system Coronary disease-Regional
myocardial blood flovu (human, dog)
ROlHL-20895-03 0007 Cineangiographic studies of
cardiovascular system - Determinants of collateral
formation (dogs, hamsters)
POlHL-20984-02 0001 Cellular mechanisms in cardiac
hypertrophy - Contractile proteins in cardiac hypertrophy
(rabbits, calves)
** POlHL-209 84-02 0005 Cellular mechanisms m cardiac
hypertrophy - Neurohumoral receptors in cardiac grov»th
and compensatory hypertrophy (animals)
POlHL-21016-02 0013 Sickle cell anemia and other
hemoglobinopathies - Microcirculatory response to sickle
cell treated with anti-sickling agents (rats)
R23HL-21083-02 Pharmacokinetics of digoxin and digitoxin
in humans (rats)
ROlHL-21105-02 Organ specific drugs-Cardiovascular and
renal effects (dogs)
ROlHL-21 158-02 Cardiac receptors with vagal C-fiber
afferents (cats)
ROlHL-21182-02 Active tension and shortening in cardiac
hypertrophy (rabbits)
ROlHL-21 195-02 Innervation of the heart -Acetylcholine
receptors (frogs)
R23HL-2 11 96-02 Digitalis induced arrhythmia and NAO nu-
atpase activity (dogs)
ROlHL-21245-02 Influence of chronic exercise on
hypertension (rats, primates)
R23HL-21262-02 Sodium-calcium interactions in
mammalian myocardium (rabbits, cats)
R23HL-21298-02 Coronary vasomotion (dogs, pigs)
R23HL-21325-02 Sarcomere kinematics in cardiac
contraction (rats, rabbits)
R23HL-21368-02 Perinatal cardiac electrophysiology (dogs)
ROlHL-2142902 Transport of LDL in arterial wall (human.
mammals) , ^ i
ROlHL-21438-02 Structure and permeability ot arterial
endothelium (pigs)
ROlHL-21457-01 C(17)-side group geometry and
cardenolide activity (cats, guinea pigs)
R23HL-21462-02 Mechanical interactions between ventricle
arteries (dogs)
ROlHL-21476-02 Anticoagulant drug absorption
interactions (rats)
ROlHL-21548-01 Pathogenesis of pulmonary
thromboembolic disease (human, mammals)
R23HL-21559-01 Oxygen supply and blood flow through
aortic vasa vasorum (dogs)
ROlHL-21654-01 Autonomic determinants of arrhythmia
due to ischemia (cats)
** ROlHL-2167201 Antiarrhythmic drug action on VMAZ of
cardiac cells
ROlHL-21690-02 Sequential multinuclide study of acute
infarction (human, dogs)
ROlHL-21735-01 Electrophysiology after healed myocardial
infarction (cats)
ROlHL-21742-01 Frequency-dependent drug actions in
cardiac muscle (rabbits)
ROlHL-21751-02 0001 Thallium and antimyosin in
ischemia and infarction - In vitro models of ischemia and
infarction (rats, mice)
ROlHL-21751-02 0002 Thallium and antimyosin in
ischemia and infarction - Canine models of ischemia and
infarction
ROlHL-21751-02 0003 Thallium and antimyosin in
ischemia and infarction - Human studies-Ischemia and
infarction
** ROlHL-21812-02 Actions of drugs and ions on cardiac
membranes (rabbits, guinea pigs)
ROlHL-21817-01 Catecholamines, blood pressure and
circulation
ROlHL-21877-01 Isorenins in the hypertensive rat
CAR
R23HL-21950-01 Endothelial cell mechanisms in vascular
disease (human)
ROlHL-21969-01 Prevention of myocardial hypoxia during
by-pass (rats. mice, squirrels)
R23HL-21973-01 Catecholamine metabolism and the heart
(human, guinea pigs)
ROlHL-21994-01 Structure and development of
regenerating capillaries (rabbits, chick embryo)
ROlHL-22064-02 Glycogen metabolism in anoxic diabetic
myocardium (rats)
ROlHL-22069-02 Experimental renal arterial hypertension
(dogs)
ROlHL-22080-01 Phosphorus NMR studies on cardiac
tissue (rats, rabbits)
ROlHL-22098-01 Is postoperative infarction due to
repertusion injury? (human, dogs)
ROlHL-22135-01 Control of calcium fluxes across cardiac
membranes (dogs, rabbits, guinea pigs)
ROlHL-22216-02 Vascular mechanisms in renal
hypertension (dogs)
ROlHL-22219-01 Prostacyclin and peroxides in blood and
membrane disease
ROlHL-22223-01 The cardio-pulmonaiy junction (dogs,
models)
ROlHL-22225-01 Hormonal regulation of blood pressure
and blood flow (human, animals)
ROIHL 22265-02 Isozymes of heart glutamate aspartate
transaminase (swine, ducks)
ROlHL-22269-01 Excitation-contraction coupling in
enlarged hearts (rabbits)
ROIHL 22273-01
(rats)
" R23HL-22309-01
immature dogs
** ROlHL-223 54-01
metabolism (rats)
ROlHL-22445-01 Platelet inhibitors-Effect on coronary
bypass grafts (dogs)
ROlHL-22455-01 Platelet concentration in the marginal
layer (dogs, human) ■ , ,
ROlHL-22470-01 Liposome myocardial uptake in infarct
and ischemia (dogs, rats, mice)
ROlHL-22484-01
excitation (dogs)
ROlHL-22506-01
Oral and lung absorption of nitroglycerin
Cardiovascular pharmacodynamics in
Alpha-adrenergic effects on heart
hypertensions
ROlHL-22522-01
antagonists
ROlHL-22527-01
Neural control of cardiac conduction and
Hemodynamics of the clinical
Cardioselectivity of beta-ad renoceptor
Prostacyclin-thromboxanes in the
cardiovascular system (human, rabbits)
ROlHL-22566-01 Mesoionic purinones as
phosphodiesterase inhibitors
R23HL-22575-01 Factors modifying cardiac digoxin effects
and content (dogs, cats)
ROIHL 22581-02 Neurocirculatory control in diabetes
mellitus (human)
ROIHL 22583-02 Ultrastructural study of endothelium in
thrombosis (human)
ROlHL-22603-01 Trace metals, vascular activity and
hypertension (rats)
R23HL-22669-01 Cardiovascular effects from visceral
afferents (dogs)
ROlHL-22685-01 Drugs and excitation-contraction coupling j
In heart (animals)
ROlHL-22715-01 Neural integration of the cardiovascular
reflexes (dogs))
ROlHL-22718-01 Cardiovascular drug interactions-
Metabolism models (dogs)
ROlHL-22732-01 Central organization of cardiac afferent
nerves (cats, monkeys)
ROlHL-22783-01 Hemodynamic induction of Intimal
fibromuscular lesion
ROlHL-22801-01 Analysis of coronary artery behavior
(dogs)
ROlHL-22815-01 Regional myocardial function after
revascularization (dogs)
' ROIHL 22862-01 CNS-mediated effects of antiarrhythmic
drugs (dogs)
R01HL-22896-01 Immediate metabolic fates of kinins ana
angiotensins (rat. rabbit, guinea pig)
* ROlHL-22946-01 Prostaglandins, platelet aggregation and
vasoactivity (human, rats, rabbits)
R23HL-22959-01 Heart development in inherited
cardiomyopathy (hamsters)
R23HL-22972-01 Microcirculatory function in hypotension
Adaptive heart growth in neonates and
(rats, hamsters)
ROlHL-23025-01
adults (rats)
ROlHL-23171-01 Coronary collateral circulation in
myocardial ischemia (dog. pig. rat. human)
ROlHL-23210-01 Biology of normal and hypertrophied
pulmonary vessels (cat. human)
ROlHL-23211-01 Active normoxic pulmonary vasodilatation
(rat. dog. sheep)
ROlHL-23312-01 Hemodynamics and vasoactivity in renal
hypertension (human, dogs)
• ROlHL-23599-01 Mechanisms of ischemic rhythm
disorders (dogs)
ROlHL-23603-01
disease (rats)
ROlHL-23604-01
mechanisms (rat)
Morphogenesis of hypertensive vascular
Hepatic microvascular regulatory
(contd)
•Excludes routine methodotogy OR covers only general projects which preclude
'•Oriented significantly to above subject.
Indexing at the specific level.
M Grant has subptojects describing specific research aspects.
See Appendix for Investigator's name and grant number
CAR
ROIHl 23624 01 Etttcl of dni|> on lichtmlc Cirdlic ctlls
(do|>. |uin«i pigj, pl|s)
ROIHL 23;;6 01 Tnatmfnt of vanttlcular tfihythmias with
proprinolol (human)
ROIHI 23980 01 Effects ol dlgomn ttieiapy in newborn
and adult slieep
ROIHL 23990 01 Role ol phosphoprotaln in cardiac
inotropic responses
IM)1HV2291S 11 Establishment of lipid research clinic
NOIHV 72939 01 Develop and evaluate left heart assist
blood pumps (human, calves, pigs)
CARDIOVASCULAR PROSTHESIS
SEE ALSO HEART PROSTHESIS
POIHL 13330 08 00b6 Mechanical circulatory support
Blood compatibility linings (calves)
ROIHL 16938 OS Effect of physical farces on blood (dogs.
human)
ROIHL 17623 OS Initial events in thrombus formation on
surfaces (human, rats)
ROIHL 177S1 03 Experimental endocarditis (rabbits)
** ROIHL 18639 03 Human anatomy lor cardiac prostheses
(human) ,
ROIHL 2200801 Left ventrivular calcium content and
contractility (rats)
M POIHL 2216301 Surface thrombogenesis Mechanisms and
prevention
POIHL 2216301 0001 Surface thrombogenesis-
Mechanisms and prevention Initial blood protein and
platelet interactions with biomaterials (baboons)
PO1HL2216301 0002 Surface thrombogenesis-
Mechanisms and prevention Laser scattering detection of
microemboli in blood flow (baboons)
POIHL 22163 01 9001 Surface thrombogenesis-
Mechanisms and prevention - Polymers for studing blood
material interactions core
R01HL22338-01 Platelet adhesion and aggregation in a
flow chamber (human)
ROlHL-22661-01 Chronic total cardiopulhonary mechanical
substitution (sheep)
NOlHV-42961-06 Evaluation of biomaterials in contact
with blood (dogs)
NOlHV-72919-01 Test polymers for circulatory assist
divices
CARDIOVASCULAR PROSTHESIS, BLOOD
VESSELS PROSTHESIS
POlHL-04664-18 0001 Cardiovascular and lung dynamics
■ X-ray projection image videodensitometry (dogs)
** POlHL-06312-17 0048 Surgical cardiology - Use of an
adjustable pulmonary artery band (dogs)
** POlHL-06370-17 0013 Cardiopulmonary and renal
pathology research center - Morphologic analysis of
vascular prosthesis (human, dogs)
** P01HL-I3737-07 0032 Assisted circulation - The dynamic
aortic patch (human, dogs)
POlHL-13738-08 0001 Cardiac assist devices and
artificial hearts - Cardiac assist devices (human, sheep)
POlHL-13738-08 0005 Cardiac assist devices and
artificial hearts - Development of new materials for
artificial heart and assist devices (sheep, dog)
** R01HL-I3803-07 Advanced cardiac valvular and vascular
prosthesis (dogs, baboons)
ROlHL-14126-17 Effect of function on grafts and implants
of collagen (dogs, monkeys)
POlHL-15195-04 0004 Program project in biological
materials - Biological evaluation and surface interaction
studies (dogs)
" POlHL-16387-04 0006 The blood vessel and
thrombogenesis - Mechanism of delayed vessel graft failure
(dogs, rabbits)
ROlHL-17973-04 Cultured aortic endothelial cells (human,
cattle, dogs, swine)
ROIHL- 1844 1-03 Guidelines for polymers acting as elastin
substitutes
POlHL-18576-03 0001 Thrombosis research program
project - Platelet damage from physical forces and
artificial surfaces (human)
** POlHL-18576-03 0010 Thrombosis research program
project - Evaluation of non-thrombogenic materials (cattle)
** ROlHL-18644-03 Prosthesis for aortocoronary bypass
(dogs, baboons)
** ROlHL-18764-03 Biosorbable thromboresistanl surfaces
(dogs, rats, swine, human)
ROlHL-20163-02 Competitive coronary flow in native and
graft vessels (dog)
** R0IHL21001-01 Protein and thrombus deposition on
vascular grafts
** R23HL-2 1805-0 1 Tissue cell interactions with vascular
prostheses (human, rats, mice)
ROlHL-221 10-02 Healing complications in vascular
grafting (dogs)
** ROlHL-22445-01 Platelet inhibitors -Effect on coronary
bypass grafts (dogs)
ROlHL-23899-01 Flow and flexing at blood/biomaterial
interfaces
NOlHV-12060-18 Tissue cultured endothelium for vascular
prosthetic devices (human, animals)
** NOlHV-42928-07 Continued development of carbon film
deposits for prosthetics
** NOlHV-62911-04 Vena cava ring tests of biomaterials in
dogs
133
CARDIOVASCULAR SHUNTS ABNORMAL
Sf( CAROIOVASCIIIAR DISOHOI RS AIIIIRIOVINOUS SHUNTS
AUNURMAI
SEE CONUINIIAI ABNORMALITIES, CARDIOVASCULAR SHUNTS
AHNORMAI
CARDIOVASCULAR SHUNTS DUCTUS
ARTERIOSUS EMBRYONIC
SEE CARDIOVASCULAR SYSTEM, DUCTUS ARTERIOSUS
EMBRYONIC
CARDIOVASCULAR SHUNTS NORMAL
SEE CARDIOVASCULAR SYSTEM. ARTIRIOVFNOUS
ANASTOMOSIS NORMAL
CARDIOVASCULAR SHUNTS SURGICAL
SEE CARDIOVASCULAR SURGERY. CARDIOVASCUUR SHUNTS
CARDIOVASCULAR SURGERY
SEE ALSO BLOOD TREATMENT. BIOOD FILTERS
SEE ALSO CEREBROVASCULAR SURGERY
SEE ALSO HEART SURGERY
" POIHL 11310 12 0064 Mechanisms of cardiovascular
disease Extracardiac anatomical correction of
transposition of great arteries (puppies)
ROIHL 11945 10 Synthesis of artificial lung and kidney
systems (sheep, mice, swine)
ROIHL 16921-05 Synthetic hydrogels as blood tolerable
materials
P60HH 7269-04 0004 National heart and blood vessel
research and demonstration center Atherosclerosis -
Clinical surgical aspects (human)
** P60HL 1726904 0024 National heart and blood vessel
research and demonstration center Section of
experimental cardiovascular surgery -Core facility
ROlHL-17358-04 Ventilatory adjustments for optimal
oxygenation (dogs, rats)
R01HL-18519-03 Albumin, endothelium and
hemocompatibility (human, dog. cattle, rabbit)
ROlHL-18639-03
(human)
** ROlHL-188 15-03
Human anatomy for cardiac prostheses
Surgical vascular disorders (human.
dogs)
ROlHL-19673-03 Surgical aspects of shock and hypoxia
(dogs, monkeys, rats)
ROlHL-20251-02 A novel approach to nonthrombogenic
polymer surfaces (sheep, cattle)
ROlHL-203 13-02 Surface-induced thrombosis -Modification
of albumin variants (human, goat)
ROlHL-20354-02 Direct determination of oxygen tension in
the clinical environment (human, dogs)
ROlHL-20895-03 0004 Cineangiographic studies of
cardiovascular system - Cineangiography-Coronary lesions
and ventricular function (human)
ROlHL-20898-02 Ultrasonic evaluation in direct arterial
surgery (models, cattle, human)
** R01HL-21796-0I Applied pulsatile hemodynamics in
vascular surgery (dogs)
** NOlHV-32978-08 Collaborative studies on coronary artery
surgery
" NOlHV-32984-10 Collaborative studies on coronary artery
surgery (human)
CARDIOVASCULAR SURGERY, BLOOD VESSELS
RESTORATION
POlHL-13738-08 0005 Cardiac assist devices and
artificial hearts - Development of new materials for
artificial heart and assist devices (sheep, dog)
ROlHL-21796-01 Applied pulsatile hemodynamics in
vascular surgery (dogs)
CARDIOVASCULAR SURGERY, BLOOD VESSELS
RESTORATION, ENDARTECTOMY
POlHL-07293-17 0058 Non-invasive cardiovascular
measurements - Peripheral duplex scanner physiologic
evaluation
ROlHL-14126-17 Effect of function on grafts and implants
of collagen (dogs, monkeys)
ROlHL-20898-02 Ultrasonic evaluation in direct arterial
surgery (models, cattle, human)
CARDIOVASCULAR SURGERY,
CARDIOVASCULAR SHUNTS
SEE ALSO CARDIOVASCULAR SURGERY, CIRCUUTORY ASSIST
SEE ALSO CARDIOVASCULAR SURGERY, EXTRACORPOREAL
CIRCULATION
SEE ALSO LIVER CIRCULATION, VENOUS BYPASS OF LIVER
POlHL-10436-13 0008 A multidisciplinary study of
congenital heart disease - Physiologic consequences of
chronic hypoxemia (human)
POlHL-13330-08 0056 Mechanical circulatory support -
Blood compatibility linings (calves)
ROlHL-16329-04 Cardiac surgical effect on heart function
in infants (human)
** P50HL-17648-04 0013 Study of ischemic heart disease -
Fate of bypassed and bypassing vessels (dogs)
** ROlHL-18644-03 Prosthesis for aortocoronary bypass
(dogs, baboons)
** ROlHL-20037-02 Left ventricular-aortic bypass and
composite prosthesis (sheep, swine, cattle)
ROlHL-21796-01 Applied pulsatile hemodynamics in
vascular surgery (dogs)
** ROlHL-22783-01 Hemodynamic induction of intimal
fibromuscular lesion
'Excludes routine methodokigy OR covers only general projects which preclude indexing
"Chented significantly to above subject.
at the specific level.
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
CAR
CARDIOVASCULAR SUROERY,
CARDIOVASCULAR SHUNTS, ARTERIOVENOUS
(GENERAL)
" I'U I III 06 J 70 1 7 0013 Cardiopulmonary and rtnil
pathology research center Morphologic analyiii of
vascular prosthesis (human, dog^)
POIHL 1 1310 12 0091 Mechanisms of cardiovaicuUr
diieas* Noninviiive tachniquai in cardiovitculir
diagnosis (human)
POlHt 11310 12 9001 Mechanisms of cardiovascular
disease Core support hospital beds
POIHL 22163 01 0002 Surface thrombogenesis
Mechanisms and prevention Laser scattering detection of
microemboli in blood flow (baboons)
ROIHL 22259 01 Modification of susceptibility to oxygen
poisoning (rats)
** ROIHL 22741 01 Arteriovenous connections in extremity
revascularization (dogs)
CARDIOVASCULAR SURGERY, CIRCULATORY
ASSIST
SEE ALSO CARDIOVASCUUR SURGERY, EXTRACORPOREAL
CIRCUUTION
SEE ALSO HEART PROSTHESIS, AUXILIARY
SEE ALSO HEART RESUSCITATION
*• POIHL 06312 17 0040 Surgical cardiology Left ventricle
assist (dogs)
** P01HL06312 17 0042 Surgical cardiology Right
ventricular assist device (sheep)
** POIHL 06312-17 0043 Surgical cardiology The
cylindrical ventricular assist device (dogs)
POIHL 10539 12 0069 Pathophysiology of circulation
Ventricular compliance and mechanics in intact ventricles
(human)
M POIHL 1333008 Mechanical circulatory support
** POIHL 1333008 0031 Mechanical circulatory support
Hemodynamics of cardiac prosthesis
** POlHL-1333008 0034 Mechanical circulatory support In
vivo test and evaluation of left ventricular bypass pumps
(human, cattle)
** POIHL 13330-08 0056 Mechanical circulatory support -
Blood compatibility linings (calves)
** POIHL 13330-08 0059 Mechanical circulatory support -
Physiologic evaluation of circulatory assistance (cattle)
** POlHL-13330 08 0062 Mechanical circulatory support -
CORE facilities
M POlHL-13737-07 Assisted circulation
" POIHL 13737-07 0002 Assisted circulation - U-shaped
mechanical auxiliary ventricle (dogs)
** POlHL-13737-07 0005 Assisted circulation - Piezoelectric
assist device (animals)
** POlHL-13737-07 0007 Assisted circulation -
Determination of cardiac status by use of balloon pump
(dogs)
** POlHL-13737-07 0008 Assisted circulation - Phase-shift
balloon pumping alternate designs
** POlHL-13737-07 0009 Assisted circulation - Analytical
models
** POlHL-13737-07 0013 Assisted circulation - Incorporation
of sensors (human, dogs)
** POlHL-13737-07 0024 Assisted circulation - Dynamic
prosthetic myocardium (dogs)
" POlHL-13737-07 0025 Assisted circulation - Driving
system based on quantitative criteria (human, dogs)
** POlHL-13737-07 0026 Assisted circulation ■ Hemostatic
mechanism (human, dogs)
** POlHL-13737-07 0027 Assisted circulation - Optimization
of cardiac assistance (dogs)
** POIHL 13737-07 0028 Assisted circulation - Clinical
studies of intraaortic balloon pumping
** POlHL-13737-07 0030 Assisted circulation - Myocardial
ischemia-Effects of phase-shift balloon pumping (dogs)
** POlHL-13737-07 0031 Assisted circulation - Myocardial
ischemia-Biochemical changes (dogs)
" POlHL-13737-07 0032 Assisted circulation - The dynamic
aortic patch (human, dogs)
** POlHL-13737-07 0034 Assisted circulation - Phasic aortic
flow and cardiac output from phasic pressures (dogs)
** POlHL-13737-07 0036 Assisted circulation - Assessment
of infarct size from hemodynamic measurements
** POlHL-13737-07 0039 Assisted circulation - Computer
controlled intraortic balloon pumping
M POlHL-13738-08 Cardiac assist devices and artificial
hearts
** POlHL-13738-08 0001 Cardiac assist devices and
artificial hearts - Cardiac assist devices (human, sheep)
** POlHL-13738-08 0004 Cardiac assist devices and
artificial hearts - Hematological evaluation of prosthetic
materials (calves)
** POlHL-13738-08 0005 Cardiac assist devices and
artificial hearts - Development of new materials for
artificial heart and assist devices (sheep, dog)
** P60HL- 17269-04 0029 National heart and blood vessel
research and demonstration center - Clinical application of
circulatory assistance (human)
** P60HL-17269-04 0030 National heart and blood vessel
research and demonstration center - Cardiovascular
engineering laboratories (human)
ROlHL-18672-03 Dynamic studies of clot structure
formation (human)
** ROlHL-18948-03 Pulseless flow and circulatory assistance
(dogs, calves)
(contd)
CAR
** NOlHV-42914-13 Solenoid left ventricular assist system
(cattle)
** NOlHV-53006-06 Evaluation of model VII left ventricular
assist device (human)
** NOlHV-53008-07 Left ventricular assist device-Clinical
evaluation (human)
** NOlHV-72918-01 Test polymers for circulatory assist
devices
** NOlHV-72919-01 Test polymers for circulatory assist
divices
** NOlHV-72934-01 Development of a left heart assist blood
pumps (human, cattle)
** NOlHV-72936-00 Left heart assist device development
(human, cattle)
** NOlHV-7293700 Left heail assist blood pumps (calves)
** NOlHV-72938-01 Development of a left heart assist blood
pump
** NOlHV-72939-01 Develop and evaluate left heart assist
blood pumps (human, calves, pigs)
** NDlHV-72971-01 Energy converters to control heart assist
devices (human, cattle)
** NOlHV-72975-02 Energy converter tor left ventrical assist
devices (calves)
** NDlHV-72976-02 Energy converters to control heart assist
devices (human, cattle)
CARDIOVASCULAR SURGERY, CIRCULATORY
ASSIST, BLOOD OXYGENATORS
** ROlHL-11945-10 Synthesis of artificial Ijjng and kidney
systems (sheep, mice, swine)
ROlHL-12839-09 Flow, transport and membrane
phenomena in blood (human)
POlHL-13330-08 0031 Mechanical circulatory support -
Hemodynamics of cardiac prosthesis
P01HL1333008 0034 Mechanical circulatory support - In
vivo test and evaluation of left ventricular bypass pumps
(human, cattle)
ROlHL-14644-05 Optimization diastolic augmentation and
systolic sink (dogs)
** ROlHL-15593-05 Prolonged extracorporeal cardiopulmonary
support (rats, sheep, rabbits)
** ROlHL-16582-05 Artificial lungs (dogs)
P60HL-17269-04 0029 National heart and blood vessel
research and demonstration center - Clinical application of
circulatory assistance (human)
ROlHL-19055-03 Platelet function during extracorporeal
perfusion (human, mammals)
** ROlHL-19173-03 Analysis of blood trauma from
microporous oxygenators (human, dogs, rabbits)
** ROlHL-21194-02 Development of antithrombogenic plastic
biomaterials
** R23HL-21271-02 Extracorporeal circulation and protein
denaturation (human)
** ROlHL-22315-01 Intraoperative cardiac oxygen supply-
demand (dogs, rabbits, rats)
R23HL-22346-01 Hematological injury and pulmonary
dysfunction (human, mammals)
ROlHL-22627-01 An inhibitor of platelet adhesion to
artificial organs (human)
CARDIOVASCULAR SURGERY, CIRCULATORY
ASSIST, COUNTERPULSATION
POlHL-06285-18 0155 Cardiovascular-respiratory
physiology and biochemistry - Therapeutic alterations,
contractile state in heart failure
** POlHL-06312-17 0041 Surgical cardiology - A
servomechanism for left ventricular assist (human, dogs,
sheep)
** ROlHL-07139-17 Cardiodynamics and metabolism of
congestive failure (human, dogs)
P01HL-12738-10 0081 Physiologic pharmacology and its
clinical applications - Ultrastructural and electrophysiologic
alteration of myocardium (human, dogs)
** P01HL12738-10 0123 Physiologic pharmacology and its
clinical applications - Ventricular assistance and
preservation (human, dogs)
** POlHL-12738-10 0124 Physiologic pharmacology and its
clinical applications - Counterpulsation on myocardial
ischemia measured by carbon dioxide tension (dogs)
POlHL-13330-08 0034 Mechanical circulatory support ■ In
vivo test and evaluation of left ventricular bypass pumps
(human, cattle)
** ROlHL-14644-05 Optimization diastolic augmentation and
systolic sink (dogs)
** P60HL-17269-04 0029 National heart and blood vessel
research and demonstration center - Clinical application of
circulatory assistance (human)
** P50HL 17648-04 0011 Study of ischemic heart disease -
Surgical treatment for acute myocardial ischemia (human,
dogs)
P50HL-1 766504 0021 Study of ischemic heart disease -
Identification, prevention -Myocardial ischemia in
cardiopulmonary bypass (dog)
** P50HL- 17669-04 0012 Ischemic heart disease center
(SCOR) - Circulatory assistance (human, dog)
CARDIOVASCULAR SURGERY, CIRCULATORY
ASSIST, DIASTOLIC AUGMENTATION
POlHL-06285 18 0155 Cardiovascular respiratory
physiology and biochemistry Therapeutic alterations,
contractile state in heart failure
•* ROlHL-14644-05 Optimization diastolic augmentation and
systolic sink (dogs)
124
P50HL-17651-04 0016 Ischemic heart disease specialized
center of research - Retroperfusion of coronary venus
circulation with therapeutic agents (dogs)
CARDIOVASCULAR SURGERY, CIRCULATORY
ASSIST, HEART BYPASS SURGICAL
** POlHL-10436-13 0006 A multidisciplinary study of
congenital heart disease - Ventricular blood pumps and
valves (human, cattle)
POlHL-11310-12 0095 Mechanisms of cardiovascular
disease - Blood and transfusion disorders (human, rats,
monkeys)
ROlHL-12307-08 Non-surgical treatment of congenital
heart disease (human, dogs)
ROlHL-12322-10 Extrinsic factors influencing myocardial
performance (dogs, swine)
** POlHL-12738-10 0098 Physiologic pharmacology and its
clinical applications - Skeletal muscle support of the
chronically failing heart (dogs)
ROlHL-13426-09 Left ventricular bypass for myocardial
infarction (cattle, human)
POlHL-13738-08 0001 Cardiac assist devices and
artificial hearts - Cardiac assist devices (human, sheep)
** ROlHL-14378-07 Lipemias and reconstructive cardiac
surgery (human)
ROlHL-14644-05 Optimization diastolic augmentation and
systolic sink (dogs)
** ROlHL-19030-03 Tissue protection during circulatory
interruption (dogs)
ROlHL-19203-03 Surgical approach to congenital heart
diseases (dogs, primates)
** ROlHL-20637-02 Recovery after heart surgery-Bio-
behavioral factors (human)
CARDIOVASCULAR SURGERY, CIRCULATORY
ASSIST, HEART-LUNG BYPASS
ROlHL-05875-18 Pathologic metabolic and physiologic
studies of heart (human, dogs, cats)
POlHL-06285-18 0143 Cardiovascular-respiratory
physiology and biochemistry - Myocardial ischemia (human,
dogs, lambs)
POlHL-063 12-17 0041 Surgical cardiology - A
servomechanism for left ventricular assist (human, dogs,
sheep)
POlHL-06312-17 0046 Surgical cardiology - The
relationship of prostaglandins to heart disease
** POlHL-06312-17 0047 Surgical cardiology - Myocardial
extravascular water (dogs)
ROlHL-08696-15 0020 Orthotopic heart transplantation -
Complete cardiopulmonary transplantation (dogs)
R01HL-09609-11 Lung volume and breathing mechanics
during anesthesia (human)
** POlHL-11310-12 0053 Mechanisms of cardiovascular
disease - Ventricular pressure-volume after cardipulmonary
bypass (dogs)
POlHL-1 13 10-12 0062 Mechanisms of cardiovascular
disease - Myocardial depressant factor in postoperative
cardiac dysfunction (human, dogs)
POlHL-1 13 10-12 0063 Mechanisms of cardiovascular
disease - Myocardial function, metabolism and cellular
integrity after heart surgery (dogs)
POlHL-1 13 10-12 0064 Mechanisms of cardiovascular
disease - Extracardiac anatomical correction of
transposition of great arteries (puppies)
POlHL-11310-12 0074 Mechanisms of cardiovascular
disease - Electrophysiological studies of paraxysmal atrial
tachycardia (human)
POlHL-12738-10 0094 Physiologic pharmacology and its
clinical applications - Ventricular function and structure
(human, dogs)
** POlHL-12738-10 0122 Physiologic pharmacology and its
clinical applications - Coronary perfusion of beating and
fibrillating hearts (dogs)
** POlHL-12738-10 0123 Physiologic pharmacology and its
clinical applications - Ventricular assistance and
preservation (human, dogs)
ROlHL-133 15-08 Disposition of vasoactive hormones in
mammalian lung (rats, rabbits, human)
P01HL13330-08 0031 Mechanical circulatory support -
Hemodynamics of cardiac prosthesis
POlHL-13330-08 0034 Mechanical circulatory support - In
vivo test and evaluation of left ventricular bypass pumps
(human, cattle)
** ROlHL-15813-05 Cardiac anoxia -Protective effect of
carbohydrate (dogs)
** ROlHL-161 54-05 Membrane lung perfusion for acute
respiratory failure (sheep, baboons)
** ROlHL-16292-05 0002 Surgery and non-obstructive
coronary insufficiency - Effects of hypothermia during
cardiopulmonary bypass (dogs)
** ROlHL-1629205 0017 Surgery and non-obstructive
coronary insufficiency - Cardiopulmonary resuscitation
(human)
** ROlHL-16292-05 0018 Surgery and non-obstructive
coronary insufficiency - Unavoidable subendocardial
perfusion caused by venting and hypothermia (dogs)
** ROlHL-16292-05 0019 Surgery and non-obstructive
coronary insufficiency - Distortion of subendocardial vessels
in infant hearts (dogs)
** ROlHL-16292-05 0021 Surgery and non-obstructive
coronary insufficiency - Pulsatile assistance on
subendocardial perfusion during bypass (dogs)
CAR
P60HL-17269-04 0029 National heart and blood vessel
research and demonstration center - Clinical application of
circulatory assistance (human)
P50HL-1 7648-04 0011 Study of ischemic heart disease -
Surgical treatment for acute myocardial ischemia (human,
dogs)
** P50HL-17665-04 0020 Study of ischemic heart disease -
Ischemic injury to myocardium during measured states of
ischemia (human)
** P50HL-17665-04 0021 Study of ischemic 4ieart disease -
Identification, prevention -Myocardial ischemia in
cardiopulmonary bypass (dog)
** P50HI-17667-04 0022 Study of ischemic heart disease -
Preventing myocardial injury in surgery using
cardiopulmonary bypass (human, rat)
ROlHL-18288-04 Intraoperative protection of the
myocardium (dogs, rats)
ROlHL-19055-03 Platelet function during extracorporeal
perfusion (human, mammals)
ROlHL-19105-02 Detection and adherence of fibrin
monomer complexes (human)
ROlHL-19182-03 Surgical aspects of myocatdial
hypertrophy (dogs)
** ROlHL-19414-03 Protection of myocardium during cardiac
surgery (dogs, cats, human)
ROlHL-20143-02 Hypothermic circulatory arrest -Cerebral
vascular change (dogs)
** ROlHL-20226-02 Cardiac bypass and coronary collateral
physiology (dogs)
** ROlHL-20720-02 Myocardial protection during
cardiopulmonary bypass (dogs)
ROlHL-20803-02 Intra-aortic balloon pumping (dogs,
lambs, cats)
** R23HL-21203-02 Effect of vasoactive agents on lett-to-
right shunts (lambs)
** ROlHL-21786-01 Long-term effects of myocardial
protection (dogs, rats)
** ROlHL-21969-01 Prevention of myocardial hypoxia during
by-pass (rats, mice, squirrels)
ROlHL-22 152-02 Ventricular dysfunction and cardiac
surgery (dogs)
** R01HL-22244-01 Cardiopulmonary bypass and the
vascular endothelium (dogs)
** ROlHL-223 15-01 Intraoperative cardiac oxygen supply-
demand (dogs, rabbits, rats)
ROlHL-22329-01 Active prosthetic myocardium-Effects on
LV function (dogs)
ROlHL-22661-01 Chronic total cardiopulhonaty mechanical
substitution (sheep)
ROlHL-22894-01 Two dimensional ultrasound and cardiac
surgery (human, dogs)
CARDIOVASCULAR SURGERY, CIRCULATORY
ASSIST, HEART MECHANICAL
EXTRACORPOREAL
SEE ALSO HEART PROSTHESIS, AUXILIARY
** POlHL-10436-13 0006 A multidisciplinary study of
congenital heart disease - Ventricular blood pumps and
valves (human, cattle)
** ROlHL-13426-09 Left ventricular bypass for myocardial
infarction (cattle, human)
** POlHL-13737-07 0006 Assisted circulation • Portable
driving unit for permanent assist devices (dogs)
P60HL-1726904 0030 National heart and blood vessel
research and demonstration center - Cardiovascular
engineering laboratories (human)
** P60HL-17269-04 0032 National heart and blood vessel
research and demonstration center - Clinical circulatory
assist device fabrication
ROlHL-17437-03 'Perfusion lung' -Role of traumatized
leukocytes (dogs, human)
ROlHL-17821-03 Cavitation phenomena near prosthetic
devices
ROlHL-20720-02 Myocardial protection during
cardiopulmonary bypass (dogs)
R23HL-21271-02 Extracorporeal circulation and protein
denaturation (human)
** ROlHL-22005-01 Intermittent retroperfusion of ischemic
myocardium (dogs)
** ROlHL-22661-01 Chronic total cardiopulhonary mechanical
substitution (sheep)
NOIHV 12060-18 Tissue cultured endothelium for vascular
prosthetic devices (human, animals)
** N01HV-8I388-20 Microfiber substrate for growth of intimal
linings in circulatory assist devices
CARDIOVASCULAR SURGERY,
EXTRACORPOREAL CIRCULATION
SEE ALSO BLOOD TREATMENT. HEMODIALYSIS
SEE ALSO CARDIOVASCUUR SURGERY, CIRCULATORY ASSIST
SEE ALSO CARDIOVASCULAR SURGERY, CIRCUUTORY
ASSIST, BLOOD OXYGENATORS
SEE ALSO CARDIOVASCULAR SURGERY. CIRCULATORY
ASSIST. HEART-LUNG BYPASS
SEE ALSO CARDIOVASCULAR SURGERY. CIRCULATORY
ASSIST, HEART MECHANICAL EXTRACORPOREAL
SEE ALSO KIDNEY PROSTHESIS. ARTIFICIAL KIDNEY
POlHL-06312-17 0036 Surgical cardiology - Experimental
studies of cardiac compliance (dogs)
ROIHL 11172-12 Physiology and biochemistry of
fibrinolytic enzymes (human, animals)
ROlHL-12839-09 Flow, transport and membrane
phenomena in blood (human)
(contd)
•Excludes routine methodoloey OR covers onty general projects which preclude indexing at the specific level.
**Onented signiticanthf to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigators name and grant number.
CAR
I2S
CAI
POIHL 13738 08 0003 Ciidiac assist dtvlcn ind
•ililicial hearts Pathophysiological ellgcis ol tht artlllcial
haail (caivas)
" ROIHL 1SS93 0& Prolonied Mttacorporcal cardiopulmonaiY
support (rats, shaap. rabbits)
ROIHI \6\bi Ob Mambrar)« lung ptrtusion lor acuta
raspiiatorv lailura (shaap. baboons)
P50HL 17648 04 0012 Study ol ischamic heart disease
Retrograde coronary venous perfusion Acute niyocardial
ischemia
POIHL 18!i;603 OOCl Thrombosis research program
prolect Platelet damage tram physical forces and
artlllcial surfaces (human)
** R01HL'190SS 03 Platelet lunction during extracorporeal
perfusion (human, mammals)
R01HL'193S0 02 Prevention ol thrombosis by applied
electric fields (sheep)
ROIHL 1972S03 Complement induced pulmonary in|ury
(dogs, rabbits, sheep)
R01HL2U9402 Development ol antithrombogenic plastic
biomalerials
** R23HL 21271 02 Extracorporeal circulation and protein
denaturation (human)
ROIHL 22329 01 Active prosthetic myocardium Effects on
LV function (dogs)
R23HL'22346'01 Hematological Injury and pulmonary
dysfunction (human, mammals)
CARDIOVASCULAR SURGERY,
EXTRACORPOREAL CIRCULATION, CROSS
CIRCULATION
SEE ALSO BLOOD TRANSFUSION
ROIHL 11901 12 0004 Effects of metabolic surgery on
the hyperlipidemias Ileal bypass-Cholesterol dynamics
studies (rats, rabbits, dogs)
P01HL1743005 0001 Control of coagulation - Porcine
von Willebrand's disease
CARDIOVASCULAR SURGERY,
REVASCULARIZATION SURGICAL
SEE ALSO HEART REVASCUURIZATION
SEE ALSO KIDNEY SURGERY. KIDNEY REVASCUURIZATION
** ROlHL-14644-05 Optimization diastolic augmentation and
systolic sink (dogs)
R01HL-2089503 0002 Cineangiographic studies of
cardiovascular system - Coronary disease-Regional
myocardial blood flow (human, dog)
ROlHL-2089503 0003 Cineangiographic studies of
cardiovascular system - Densitometry in coronary stenosis
(human)
** ROlHL-22741-01 Arteriovenous connections in extremity
revascularization (dogs)
CARDIOVASCULAR SURGERY, VASCULAR
OCCLUSION THERAPEUTIC
R01HL-13341-06 Lymph-An indication of splanchnic tissue
respiration (dogs, human, rats)
** R01HL18997-02 Ischemic therapy in experimental
hypersplenism (rats, dogs)
ROlHL-19673-03 Surgical aspects of shock and hypoxia
(dogs, monkeys, rats)
ROlHL-20170-02 Pulmonary infection in splenectomized
animals (mice)
CARDIOVASCULAR SYSTEM
SEE ALSO ADRENAL CIRCUUTION
SEE ALSO CEREBROVASCUUR SYSTEM
SEE ALSO CEREBROVASCULAR SYSTEM, BRAIN CIRCULATION
SEE ALSO EYE CIRCUUTION
SEE ALSO GASTROINTESTINAL CIRCUUTION
SEE ALSO HEART
SEE ALSO HEART CIRCUUTION
SEE ALSO KIDNEY CIRCUUTION
SEE ALSO LIVER CIRCUUTION
SEE ALSO PREGNANCY CIRCUUTION
SEE ALSO RESPIRATORY CIRCUUTION
SEE ALSO SKELETAL SYSTEM CIRCUUTION
SEE ALSO SKIN CIRCUUTION
** R01HL-05883-18 0005 Reflex control of resistance and
capacitance vessels - Differential blockade of medullated
and non-medullated vagal afferents in the cat
P01HL08805-15 0050 Regulation of ventilation and
pulmonary circulation - Right ventricular mechanics (dogs)
** POIHL-12373-10 0016 Cardiopulmonary physiology and
pathophysiology - Hislology-histochemistry-Gough laboratory
** P01HL12373-10 0018 Cardiopulmonary physiology and
pathophysiology • Biochemistry laboratory
** ROlHL-1264708 Inactivation of norepinephrine in vascular
tissue
** P01HL12738-10 0065 Physiologic pharmacology and its
clinical applications • Psychothcropeutic drugs and
cardiovascular system (human, rats)
POlHL-13262-07 0023 Arterial wall in atherosclerosis ■
Isolation and characterization of soluble elastin
P01HL14388-07 0153 Regulation of the circulation in
pathological states - Subcellular distribution of calcium
(rats)
POlHL-1438807 0154
pathological states -
contraction (rats)
POlHL-14388-07 0159
pathological states -
blood pressure development (rats)
Regulation of the circulation in
Energetics of smooth muscle
Regulation of the circulation in
Early drug and diet interventions and
POIHL 143BI>07 0160 NeguUlion ol the circulation in
pilhologlcal itttM ' Miichanisni ol the aniihypertensive
ellect ol tfilnlni Irits)
POIHI 14388 07 0164 Regulation ol the circulation in
pathological states Hyperkinetic heart syndrome (human)
POIHI 14388 0/ 0165 Regulation ol Iho circulation in
pathological states Vascular resistance in experimental
atherosclorosis in Rhesus monkeys
POIHI 14388 07 0166 Regulation ol the circulation in
pathological states Elastic changes in abdominal aortti
with atherosclerosis (Rhesus monkeys)
POIHL 1438807 0167 Regulation ol the circulation in
pathological states Increased reactivity ol artery vascular
muscle in spontaneously hypertensive rat
POIHL 1438807 0168 Regulation of the circulation in
pathological states Ionic basis ol depolarization (rats,
tissue culture)
POIHL 14388 07 0172 Regulation of the circulation In
pathological states cAMP dependent protein kinase from
heart and vascular smooth muscle (guinea pigs)
POIHL 1438807 0178 Regulation ol the circulation in
pathological slates Structural and lunctional
consequences ol denervation (rats)
POIHL 14388 07 0179 Regulation of the circulation in
pathological states Cultured muscle cells and their cross-
innervation m vitro (rats, sheep)
POIHL 14388 07 0183 Regulation of the circulation in
pathological states Vasopressin in cardiovascular
regulation (dogs, rats)
POIHL 1438807 0204 Regulation of the circulation in
pathological states ■ Reflex control of vascular resistance
in spontaneously hypertensive rats
POlHL-14388 07 0208 Regulation ol the circulation in
pathological states Baroreceptor reflex lunction in normal
and hypertensive man
POlHL-14388'07 0229 Regulation of the circulation in
pathological states - Mechanism of postural hypotension
(human)
ROlHL-17921-04 Peroxy radicals to prostaglandins in
vessels and lung
R01HL18601-01
adenosine (rats)
R01HL187 14-04 Cardiovascular matrix -Morphogenesis
and maturation (human, chick embryo, mammal)
ROlHL-19066-03 Synthesis and evaluation of
prostaglandin metabolites (guinea pigs)
R01HL-19082-01
smooth muscle
R01HL196 53-03
Regulation of neurotransmitter release by
Hypoxia-induced relaxation of vascular
Circulatory system effects of angiotensin
analogs (rats)
R01HL-20787-G2 Thromboxanes and prostaglandins-
Biochemical pharmacology (rabbits, human)
POlHL-2260201 0002 Pathophysiology of the
endothelium - Molecular charge and endothelial
permeability (rats, mice)
** R23HL-22669-01 Cardiovascular effects from visceral
afferents (dogs)
NOlHV-52971-06 Reexamination of Framingham heart
study cohort
CARDIOVASCULAR SYSTEM, ANGIOGENESIS
SEE ALSO CAROIOVASCUUR SYSTEM. BLOOD SUPPLY,
REVASCUURIZATION NON-SURGICAL
SEE ALSO NEOPUSMS VASCUUR SUPPLY. TUMOR
ANGIOGENESIS FACTOR
POlHL-06285-18 0125 Cardiovascular-respiratory
physiology and biochemistry - Myocardial function in the
fetal and neonatal lamb
POlHL-06285-18 0126 Cardiovascular-respiratory
physiology and biochemistry ■ Ventricular output, foramen
ovale and ductus arteriosus flows (lambs)
POlHL-06285-18 0127 Cardiovascular-respiratory
physiology and biochemistry ■ Experimental congenital
cardiac lesions in fetal lambs
POlHL-06285-18 0130 Cardiovascular-respiratory
physiology and biochemistry - Ductus arteriosus-
Morphological development (human, lambs)
POlHL-06285-18 0131 Cardiovascular-respiratory
physiology and biochemistry - Fetal heart development and
ventricular outflow obstruction (lambs)
POlHL-06285-18 0136 Cardiovascular-respiratory
physiology and biochemistry - Fetal microcirculation in
utero (rabbits, lambs)
POlHL-06285-18 0179 Cardiovascular-respiratory
physiology and biochemistry - Regulation of myocardial cell
growth (rats, chick embryo)
ROlHL-06924-16 Humoral and metabolic aspects of
cardiac function (mammals, non-human, human)
** ROlHL-11963-10 Biochemistry of blood vessel formation
and disease (swine)
'* ROlHL-17747 04 Endothelial injury and regeneration (rats)
R01HL19275-03 Characterization of collateral blood
vessels (dogs)
ROlHL-201 97-02 Maintenance and repair of vascular
endothelium (human, animals)
ROlHL-20381-03 Long-term study of diabetic vascular
disease (human)
ROlHL-21994-01 Structure and development of
regenerating capillaries (rabbits, chick embryo)
CARDIOVASCULAR SYSTEM, ARTERIES
SEE ALSO CEREBROVASCUUR SYSTEM. CAROTID ARTERIES
SEE ALSO CEREBROVASCUUR SYSTEM. CAROTID SINUS
SCr AIM) (;iRIHHOVA',(.UIAk '.YMIM (.(klllRAI AKIIIrll',
Sfl AISOIYI (.IRr.UIAIION OI'HIHAIMK, AHIfRY
S(i At'.OIYI CIRCUIAIION. Ml IINAI ANIIKII',
SEE AlSOHfARI VISSII!., (.ORONAHY ARIIRir,
SFE ALSO RFSPIRAIORY (JRCUIAtlON. PULMONARY ANIIRY
POIHI 031/4 23 0012 Mechanisms ol acute vascular
reaction to in|ury Human atherosclerotic plaque in organ
culture
HUIHI 03/34 18 Metabolism ol arterial tissue in
alhi^rosrlcrosr. (rabbits)
POIHI 06285 18 0156 Cardiovascular respiratory
physiology and biuchemi-^try Myocardial perlormanc*
lollowmg revasculari/alion (human)
POIHL 06835 1/ 0045 Cardir,va-.f.ulai disease Pressure
volume renin relationship in human hypertension
POIHL 08682 15 0005 Regulation ol the cardiovascular
system Smooth muscle and mechanical properties of
blood vessels (dogs, human)
ROIHL 09622 14 Pathogenesis of atherosclerosis (rals)
ROIHL 09744 14 Experimental vascular sclerosis
(monkeys, rabbits)
RGIHL 10330 11 Physiological mechanics of the heart and
arteries (dogs, rabbits, horses)
ROIHL 10612 13 0021 Humoral factors in heart failure
and hypertension The control of aldosterone secretion
(dogs)
ROIHL 10933 13 Fat metabolism and atherosclerosis
(rabbits, cattle, human, rats)
ROIHL 11289 12 Analysis ol stress in pulsatile dynamics
POIHL 11310 12 0094 Mechanisms of cardiovascular
disease Physics of pulsatile fluid How (dogs)
POIHL 11310 12 0106 Mechanisms of cardiovascular
disease - Biochemical characterization of the collagens in
vascular tissue (catte)
ROlHL-12557 09 Effects of steroids and pregnancy on
arteries and veins (guinea pigs)
ROIHL 12869-09 Arterial metabolism, diabetes and
atherogenesis (rats, rabbits)
P50HL 14138 05 0015 Center for research on
atherosclerosis Arterial wall Intermediary metabolism,
enzyme activity and bioenergetics
P50HL-14147-08 0012 Specialized center of research in
thrombosis - Tissue culture study of arterial cells (human.
hamster)
P50HL 14164-07 0035 A/S SCOR -Comparative and
experimental atherosclerosis - Lipid metabolism-Interaction
with arterial metabolism (monkey, pigeon)
P50HL-14164-07 0036 A/S SCOR -Comparative and
experimental atherosclerosis - Connective tissue
metabolism -Interaction with arterial metabolism (monkeys)
P50HL14164-07 0040 A/S SCOR-Comparative and
experimental atherosclerosis - Core angiochemistry
laboratory
P50HL-14217-08 0061 Specialized center of research in
thrombosis - Pharmacology-Comparison of platelets and
vascular smooth muscle (animal)
P50HL-14237-07 0002 Support for arteriosclerosis center
- Interactions of lipoprotein particles with vascular surface
(human, rat)
POlHL-14388-07 0151 Regulation of the circulation in
pathological states - Catecholamine release in potassium
ion-free contractures in the caudal artery
P01HL14388-07 0152 Regulation of the circulation in
pathological states - Ion flux alterations in caudal artery in
SHR
POlHL-14388-07 0153
pathological states -
(rats)
POlHL-14388-07 0167
pathological states
Regulation of the circulation in
Subcellular distribution of calcium
'Exclude: routine melhodokigy OR cavers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subproiects describing specific research aspects.
See Appendix for investigator's name and grant number.
Regulation of the circulation in
Increased reactivity of artery vascular
muscle in spontaneously hypertensive rat
POlHL-14388-07 0196 Regulation of the circulation in
pathological states - Altered vascular responsiveness in
spontaneous hypertension (rats)
POlHL-14388-07 0222 Regulation of the circulation in
pathological states - Renal perfusion pressure in
hypertension (rats)
P50HL-15062-07 0001 Study ol lipoproteins, artery wall.
and atherosclerosis Structure and molecular interactions
of serum lipoproteins (human, monkey)
P50HL-15062-07 0012 Study of lipoproteins, artery wall.
and atherosclerosis - Lipoprotein stimulation of arterial
smooth muscle cell proliferation (mammals)
P50HL-I5062-07 0019 Study of lipoproteins, artery wall,
and atherosclerosis - Factors regulating lipoprotein-smooth
muscle cell interaction (monkey)
P50HL-15062-07 0020 Study of lipoproteins, artery wall.
and atherosclerosis - Artery wall reactions -Elevated
pressure and hyperlipemia (monkey)
ROlHL-15448-06 Surgical and metabolic aspects of
venous grafts, (dogs, monkeys, rabbits)
ROlHL-15645-03 Lipid studies in vascular smooth muscle
cells (human, monkeys)
ROlHL-15979-05 Elastase. serum inhibitors and the
vasculature (human, swine)
POlHL-16387-04 0009 The blood vessel and
thrombogenesis - Role of pituitary gland in the
pathogenesis of arteriosclerotic lesions (rats)
ROlHL-16952 05 Cardiovascular pathology (rats, rabbits)
P60HL-17269-04 0001 National heart and blood vessel
research and demonstration center - Atherosclerosis -
Arterial pathology and plasma lipids (human)
(contd)
CAR
P60HL-1726904 0014 National heart and blood vessel
research and demonstration center - Physio-chemical nature
of lipid deposits in arterial wall (human)
** P60HL17269-04 0048 National heart and blood vessel
research and demonstration center - Atherosclerosis -
Lipoproteins and the arterial wall (human)
ROlHL-17401-03 Mechanisms in angiotensin induced
hypertension (cats, dogs)
ROlHL-17517-03 Arterial wall oxygen transport in
atherosclerosis (rabbits, dogs)
** ROlHL-18156-02 Hemodynamics in curved arteries
ROlHL-18157-04 Subcellular events in atherosclerosis
(human, rabbits, calves)
** ROlHL-18199-03 Effects of ions on vascular reactivity
ROlHL-18489-03 Hemodynamic interactions of vasoactive
chemicals (rats)
R01HL18516-03 Atherosclerosis and the arterial
contractile proteins (pigs, rabbits)
ROlHL-18519-03 Albumin, endothelium and
hemocompatibility (human, dog, cattle, rabbit)
** P01HL18575-03 0001 Mechanisms of vascular changes
in hypertension ■ Arteries and resistance vessels in
hypertension (pigs, rats)
POlHL-18575-03 0007 Mechanisms of vascular changes
in hypertension - Microscopy of hypertensive arterial lesions
(rats)
POlHL-18575-03 0012 Mechanisms of vascular changes
in hypertension • Anatomy core facility
R01HL18764-03 Biosorbable thromboresistant surfaces
(dogs, rats, swine, human)
ROlHL-18831-03 Microscopy of spontaneously hypertensive
arterial lesion (rats)
ROlHL-18918-03 Characterization of lung elastins (rat,
rabbit, chicken. Rhesus)
** R01HL19226-03 Vascular smooth muscle in hypertension
(rats)
R01HL19675-02 Coronary pharmacoangiography
R01HL19791-02 Ultrasonic monitoring visceral blood
vessels
ROlHL-2042903 Study of effects of diabetes reactivity
(miniature pigs, rats)
ROlHL-20439-02 Effects of insulin on neurovascular
transmission (human, rats, rabbits, hamsters)
ROlHL-20471-03 Atherosclerosis and diabetes mellitus
(human)
** ROlHL-20546-02 Chemical analysis of human arterial
elastin
** POlHL-20581-01 0004 Vascular neuroeffector
mechanisms in health and disease • Neuroeffector
characteristics of mesenteric and pulmonary blood vessels
(rabbits)
** POlHL-20581-01 0006 Vascular neuroeffector
mechanisms in health and disease - Neuroeffector
mechanism in arteries and veins in hypertension (human)
** P50HL-21006-02 0004 Specialized center of research in
arteriosclerosis - Regulation of growth of human arterial
smooth muscle cells by platelets
** ROlHL-21103-01 Parametric mechanical studies of
hypertensive arteries (dogs, rats)
** ROlHL-21270-01 Correlation of arterial hemodynamics and
morphology (human)
** R23HL-21279-02 Angiographic estimation of
atherosclerotic wall thickness
ROlHL-21665-01 Collagen polymorphism and arterial
structure (monkeys, guinea pigs)
** ROlHL-21859-01 Unsteady flow in arterial bifurcations
(human)
R23HL-22309-01 Cardiovascular pharmacodynamics in
immature dogs
** ROlHL-2232701 Transport of arterial blood gases through
skin (swine)
** ROlHL-22486-01 Enzyme regulation in cultured arterial
cells (swine)
** ROlHL-23205-01 Contraction of pulmonary vascular
smooth muscle (cat)
** ROlHL-23224-01 Hypoxia and pulmonary vascular smooth
muscle (rat. cat)
** ROlHL-23233-01 Pulmonary artery intermediate filament
structure (cattle)
** ROlHL-23542-01 Pulmonary vascular smooth muscle cell
dynamics (rat. rabbit)
CARDIOVASCULAR SYSTEM, ARTERIES,
ABDOMINAL ARTERIES
SEE ALSO CARDIOVASCULAR SYSTEM. ARTERIES. SPLENIC
ARTERY
SEE ALSO KIDNEY CIRCULATION, RENAL ARTERY
•* P01HL14388-07 0166 Regulation of the circulation in
pathological stales • Elastic changes in abdominal aorta
with atherosclerosis (Rhesus monkeys)
ROlHL-21451-01 Control of circulation during heat stress
and fever (baboon)
CARDIOVASCULAR SYSTEM, ARTERIES, AORTA
R01HL01803-23 0014 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Regenerated endothelium on lipid
accumulation in arterial wall (rabbit)
ROlHL-01803-23 0016 Arteriosclerosis, glomerulonephritis,
rtieumatic fever • Synthesis of basement membrane
collagen by endothelial cells (human)
ROlHL-01803 23 0017 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Contractile and relaxing proteins of blood
vessels and platelets (mammals, human)
126
POlHL-031 74-23 0001 Mechanisms of acute vascular
reaction to injury - Response of the vascular intima to
injury (human, rats)
POlHL-031 74-23 0013 Mechanisms of acute vascular
reaction to injury - Surface morphology of the aorta in
normal and injured states (rats, rabbits)
POlHL-06835-17 0052 Cardiovascular disease - Aortic
distensibility (human)
ROlHL-0971113 Instantaneous blood flow in ascending
aorta (human, dogs)
R01HL-10160-13 Origins of atherosclerosis (human)
ROlHL-1093313 Fat metabolism and atherosclerosis
(rabbits, cattle, human, rats)
ROlHL-11152-12 Vascular physiology (human, cats, dogs)
POlHL-11310-12 0106 Mechanisms of cardiovascular
disease - Biochemical characterization of the collagens In
vascular tissue (catte)
' ROlHL-12083-11 Flow field in aorta and its major
branches (dogs, phantom models)
' ROlHL-12561-11 Cardiovascular studies on copper
deficiency (swine)
POlHL-13262-07 0015 Arterial wall in atherosclerosis -
Crosslinkage biosynthesis in aortic elastin and collagen
(animals)
' ROlHL-13722-08 Acid and alkaline lipases in aortas (rats,
rabbits, human)
POlHL-13737-07 0013 Assisted circulation - Incorporation
of sensors (human, dogs)
POlHL-13737-07 0034 Assisted circulation - Phasic aortic
flow and cardiac output from phasic pressures (dogs)
* POlHL-13737-07 0035 Assisted circulation - Mapping the
geometry and elasticity of the aorta
P50HL-14141-05 0003 SCOR for atherosclerosis in
childhood - Detection of abnormalities in lipid metabolism
(human, rabbits, rats)
* P50HL14164-07 0044 A/S SCOR-Comparative and
experimental atherosclerosis • Cell biology-atherosclerosis
project (pigeons)
ROlHL-14344-07 Platelet function and adenine nucleotide
metabolism (human)
* POlHL-14388-07 0166 Regulation of the circulation in
pathological states - Elastic changes in abdominal aorta
with atherosclerosis (Rhesus monkeys)
POIHL- 143 88-07 0204 Regulation of the circulation in
pathological states - Reflex control of vascular resistance
in spontaneously hypertensive rats
* POlHL-14388-07 0217 Regulation of the circulation in
pathological states - Fluid mechanics of aortic flow (dogs,
human)
ROlHL-14645-07 Blood flow measurement by ultrasonic
catheter tip methods (human, dogs)
ROlHL-14775-08 Mechanisms of drug action in vascular
smooth muscle (dog. rabbits)
P50HL-15103-07 0014 A/S SCOR-Early natural history of
arteriosclerosis - Biochemistry of atherosclerotic lesions
(monkeys, human, cattle)
ROlHL-15270-06 Local mechanical properties of the aortic
tissue (dogs, pigs)
ROlHL-15478-05 Lipid flux and collagen synthesis in
atherosclerosis (rabbits)
ROlHL-15797-05 Lipid metabolism and atherosclerosis in
primates (monkeys, human, squirrels)
ROlHL-16003-08 Sources and roles of calcium in smooth
muscle excitation (rats)
ROlHL-16419-03 Arterial uptake of lipoprotein-Kinetic
analysis (rabbits)
R01HL-16577-04 Lipoprotein lipase chemistry and function
(rats, cattle, human)
R01HL-16588-05 Collagen synthesis in atherosclerosis
(dogs, rats, rabbits, human)
ROlHL-16830-05 Non-invasive determination of aortic
blood velocities (human)
P60HL-17269-04 0003 National heart and blood vessel
research and demonstration center - Atherosclerosis -Fatty
acid metabolism in cardiovascular tissue (human, chicken)
ROlHL-17371-05 Regualtion of cholesteryl ester levels in
the aorta (swine)
ROlHL-17597-05 Role of plasma lipoproteins in
atherosclerosis (swine, human)
P50HL-17648-04 0013 Study of ischemic heart disease -
Fate of bypassed and bypassing vessels (dogs)
ROlHL-17865-04 Studies on aging-Effects of sex
hormones (rats, dogs)
ROlHL-17973-04 Cultured aortic endothelial cells (human,
cattle, dogs, swine)
R01HL-18004-02 Transport through arterial wall-
Biophysical aspects (rabbits)
P50HL-183 18-03 0015 Pathogenesis and complications of
hypertension ■ Cultured smooth muscle cells and
microvessel metabolism (mammals)
R01HL18516-03 Atherosclerosis and the arterial
contractile proteins (pigs, rabbits)
ROlHL-18625-03 Organization of arterial ground substance
(cattle)
POlHL-18645-03 0004 Biology of the artery wall and
atherosclerosis ■ Human arterial smooth muscle cell and
lipoprotein interaction
** ROlHL-18736-03 Protein transport through arterial tissue
(rabbits)
R01HL-18764-03 Biosorbable thromboresistant surfaces
(dogs, rats, swine, human)
CAR
ROlHL-19830-02 Shear to aortic histamine synthesis and
permeability (dogs)
ROlHL-19936-02 Unsaturated fatty acid biosynthesis in
the aorta (rats)
** ROlHL-20037-02 Left ventricular-aortic bypass and
composite prosthesis (sheep, swine, cattle)
ROlHL-20114-02 Collagen-platelet interaction and human
aorta collagen (human)
ROlHL-20460-03 Aortic histamine synthesis in diabetes
(rat)
ROlHL-20829-02 Fluid mechanics of heart valve
prostheses (dogs, human)
POlHL-20993-02 0002 Population dynamics of arterial
cells in atherogenesis - Arterial endothelial dynamics in
atherogenesis (swine)
ROlHL-21094-01 Arterial baroreceptors and renal function
(dogs)
** R23HL-21559-01 Oxygen supply and blood flow through
aortic vasa vasorum (dogs)
ROlHL-21756-11 Vascular disease-Cytochemistry and
ultrastructure (human, rats, mice, hamsters)
ROlHL-2 1859-01 Unsteady flow in arterial bifurcations
(human)
R23HL-22309-01 Cardiovascular pharmacodynamics in
immature dogs
RClHL-23201-01 Mechanisms of hypertension (human,
rats)
CARDIOVASCULAR SYSTEM, ARTERIES, FEMORAL
ARTERY
ROlHL-18644-03 Prosthesis for aortocoronary bypass
(dogs, baboons)
ROlHL-19226-03 Vascular smooth muscle in hypertension
(rats)
R01HL-20522-03 Peripheral arterial disease in the diabetic
(human)
NOlHV-42961-06 Evaluation of biomaterials in contact
with blood (dogs)
NOlHV-72928-04 Develop high resolution ultrasonic
imaging techniques
NOlHV-72930-02 Atherosclerosis assessment-Angiography
and ultrasound (dogs, human)
CARDIOVASCULAR SYSTEM, ARTERIES, ILIAC
ARTERY
POlHL-08682-15 0005 Regulation of the cardiovascular
system - Smooth muscle and mechanical properties of
blood vessels (dogs, human)
ROIHL 12083-11 Flow field in aorta and its major
branches (dogs, phantom models)
R01HL16003-08 Sources and roles of calcium in smooth
muscle excitation (rats)
ROlHL-20766-02 Control of circulation in heat stress
(baboons)
ROlHL-21451-01 Control of circulation during heat stress
and fever (baboon)
CARDIOVASCULAR SYSTEM, ARTERIES,
MAMMARY ARTERY
** POlHL-06312-17 0015 Surgical cardiology - Internal
mammary artery versus saphenous vein for coronary artery
bypass (human)
CARDIOVASCULAR SYSTEM, ARTERIES, SPLENIC
ARTERY
ROlHL-13341-06 Lymph-An indication of splanchnic tissue
respiration (dogs, human, rats)
ROlHL-18199-03 Effects of ions on vascular reactivity
** ROIHL 18997-02 Ischemic therapy in experimental
hypersplenism (rats, dogs)
ROlHL-20086-02 Circulatory control of splenic function
(rats)
CARDIOVASCULAR SYSTEM, ARTERIOLES
ROlHL-06736-18 Biogenic-mechanical factors in
microcirculation (rats, gerbils)
POlHL-11414-11 0024 Thrombosis and atherosclerosis
program - Radiographic demonstration of small coronary
arteries (human, dogs)
ROlHL-12775-08 Cerebral microcirculation (mice)
ROlHL-12792-09 Local control of the microcirculation
(hamsters, rats)
** ROlHL-13936-06 Microvascular responses in hypertension
(human, rats)
POlHL-14388-07 0180 Regulation of the circulation in
pathological states - Regulation of cerebral blood flow
(dogs, monkeys)
ROlHL-16603-05 Human and experimental renal diseases
(animals)
** ROlHL-17335-05 Contractile properties of hypertensive
arterioles (rats)
POlHL-17421-05 0002 Regulation and exchange in the
microcirculation - Metabolic and myogenic blood flow
regulation in microcirculation (animals)
POlHL-17421-05 0004 Regulation and exchange in the
microcirculation - Localization of flow regulation in the
microcirculation (cats, human)
ROlHL-17902-04 Mammalian renal microcirculation
(hamsters)
** POIHL- 18208-04 0006 Center for the study of blood cell
rheology - Analysis of flow in arterioles and capillaries
(human)
(oontd)
*Eidu<les routine methodotogy OR covers only general projects which preclude indexing at the specific level.
**OncnMI significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigators name and grant number.
CAR
127
CAR
Surgery and non-obstructive
Effects of exercise on flow
Surgery and non-obstructive
Cardiopulmonary resuscitation
P&OHL 1831803 OOIS Palhogtnuls ind complications ol
hyptrtanslon Culturad smooth muicl* ctlls and
nilcrovtssti matabolism (mammals)
POIHI I8S7S03 0007 Mtchanisms of vascular chan|*s
In hyp«rt«nsion Microscopy ol hypertensive arttrlal lesions
(rats)
ROIHL 18831 03 Microscopy ol spontaneously hypertansiva
irt*r<al lesion (rats)
R23HL 21332 02 Pulsatll* rtgulation of How in the
microcirculation (cats)
R01HL-218S1 01 Cerebral microcirculation in expeiimental
hypertension (cats, rabbits)
ROIHL 23224 01 Hypoxia and pulmonary vascular smooth
muscle (rat. cat)
CARDIOVASCULAR SYSTEM, ARTERIOVENOUS
ANASTOMOSIS NORMAL
POIHL 06312 i; 0049 SuigicaUardiology Long term
pulmonary vascular resistance (human)
POlHL-17731 04 0003 Physiological basis of pulmonary
disease Comparative physiology (vertebrates)
ROIHL 18467 03 Fingertip blood flow in normals and
Raynaud's disease (human)
ROIHL 2089S 03 0008 Cineangiographic studies of
cardiovascular system Intercoronary anastomotic
circulation -Stenosis and occlusion (dogs)
ROIHL 22741^1 Arteriovenous connections in extremity
revascularization (dogs)
CARDIOVASCULAR SYSTEM, BLOOD SUPPLY
SEE ALSO CARDIOVASCULAR DISORDERS, ISCHEMIA
SEE ALSO CARDIOVASCUUR SYSTEM. CAPILLARY BEDS
P01HL11678-11 0043 Cardiovascular dynamics and their
control Basic mechanisms of circulatory shock (dog)
ROlHL-1 1876-11 Regional myocardial blood flow and
metabolism (dogs, swine)
P50HL-14214-07 0029 Newborn lung center for hyaline
membrane disease The diving reflex -Perinatal asphyxia.
pulmonary ischemia and HMD (sheep)
ROIHL 1629205 0002 Surgery and non-obstructive
coronary insufficiency - Effects of hypothermia during
cardiopulmonary bypass (dogs)
** ROlHL-16292-05 0009 Surgery and non-obstructive
coronary insufficiency - Exercise and supply-demand
balance (human)
ROlHL-16292-05 0010
coronary insufficiency
distribution (dogs)
♦* ROlHL-16292-05 0017
coronary insufficiency
(human)
R01HL-I8467'03 Fingertip blood flow in normals and
Raynaud's disease (human)
** ROIHL-1903903 Circulation studies by one vs two circuit
model (dogs)
ROlHL-19072-03 Modification of tissue injury in
myocardial infarction (dogs, human)
R01HL-19e7303 Surgical aspects of shock and hypoxia
(dogs, monkeys, rats)
ROlHL-20080-02 Surgically induced myocardial edema
(dogs)
ROlHL-20086-02
(rats)
** ROlHL-2013203
embryonic lung (birds)
ROlHL-2 1684-02 0002 Radionuclide infarct sizing and
therapy evaluation - Evaluating myocardial imaging agents
in global and regional ischemia (rabbits)
ROlHL-22759-01 Regional myocardial blood flow during
hypothermia (dogs)
R23HL-22972-01 Microcirculatory function in hypotension
(rats, hamsters)
CARDIOVASCULAR SYSTEM, BLOOD SUPPLY,
COLLATERAL CIRCULATION
ROlHL-09315-15 Coronary insufficiency and myocardial
revascularization (human, dogs)
ROlHL-13936-06 Microvascular responses in hypertension
(human, rats)
ROlHL-14644 05 Optimization diastolic augmentation and
systolic sink (dogs)
** POlHL-15194-07 0001 Pathophysiology of
cardiopulmonary dysfunction Coronary circulation, venous
drainage and collateral flow (human, dogs)
P50HL- 17648-04 0006 Study of ischemic heart disease -
Ventricular performance and myocardial perfusion in
obstructive coronary disease
P50HL- 17648-04 0013 Study of ischemic heart disease -
Fate of bypassed and bypassing vessels (dogs)
P50HL-1 7648-04 0021 Study of ischemic heart disease -
Biventricular contractile responses to acute myocardial
infarction (mammals)
** P50HL-17655-04 0014 Study of ischemic heart disease ■
Blood flow and gas tension in myocardial ischemia and
infarction (dog. monkey)
P50HL-1 7669-04 0012 Ischemic heart disease center
(SCOR) - Circulatory assistance (human, dog)
P50HL-1 7670-04 0006 "Study of ischemic heart disease -
Assessment of coronary artery hemodynamics and
myocardial blood flow (human)
P50HL-1 767004 0009 Study of ischemic heart disease -
Surgical treatment of localized left ventricular dyssynergy
(human, dogs)
Circulatory control of splenic function
Histogenesis and biochemistry of
PbOHl 176 70 04 0020 Study ol ischemic litmrt disease
Radionuclide evaluation ol coronary artery disease (human,
dog)
P50HI 17682 04 0016 Study ol Ischemic heart disease
Endurance exercise Prevention and rehabilitation in
Ischemic heart disease (pig)
ROIHL 1/809 04 Effects of exercise on the coronary
vasculature (rat. dog)
ROIHl 18020 04 Splanchnic hemodynamics in man
ROIHL 18060 04 Exercise and coronary atherosclerotic
heart disease (monkeys)
ROIHL 18468 03 The distribution ol flow in the
myocardium (dog, pig)
ROIHL 18560 03 Cardiovascular adaptation to stress
(miniature swine)
ROIHL 1927503 Characterization of collateral blood
vessels (dogs)
ROIHL 1993702
infarction (dogs)
ROIHL 2019002
(dogs)
ROIHL 20226-02
physiology (dogs)
ROIHL 20399-03
mellitus (dog)
ROIHL 20426-03
(dog. rat)
ROIHL 20895-03 0002 Cineangiographic studies of
cardiovascular system Coronary disease- Regional
myocardial blood flow (human, dog)
ROlHL-20895-03 0004 Cineangiographic studies of
cardiovascular system - Cineangiography-Coronary lesions
and ventricular function (human)
ROlHL-20895-03 0007 Cineangiographic studies of
cardiovascular system Determinants of collateral
formation (dogs, hamsters)
ROIHL 20895-03 0008 Cineangiographic studies of
cardiovascular system - Intercoronary anastomotic
circulation -Stenosis and occlusion (dogs)
ROlHL-21034-01
occlusion (dogs)
ROlHL-21657-01
Vasodilators in experimental myocardial
Pathogenesis of cardiac hypertrophy
Cardiac bypass and coronary collateral
Vascular control in experimental diabetes
Myocardial function in diabetes mellitus
Compensatory responses to arterial
Regional nonischemic myocardial
Myocardial perfusion in the hypertrophied
hypoxia (dogs)
R01HL-21872-01
heart (dogs)
ROlHL-22005-01 Intermittent retroperfusion of ischemic
myocardium (dogs)
ROlHL-22172-01 Hypotension, renal ischemia and effect of
mannitol (dogs, rats)
ROlHL-22741-01 Arteriovenous connections in extremity
revascularization (dogs)
R01HL-22917-01 Microvascular pressures in the intact
beating heart (rabbits)
ROlHL-23 138-01 Myocardial ischemia (dogs, rats, chick
embryo)
** ROlHL-23171-01 Coronary collateral circulation in
myocardial ischemia (dog, pig, rat. human)
ROlHL-23970-01 Mechanisms and control of sudden
cardiac death (human, dog)
CARDIOVASCULAR SYSTEM, BLOOD SUPPLY,
REVASCULARIZATION NON-SURGICAL
SEE ALSO CARDIOVASCULAR SURGERY. REVASCULARIZATION
SURGICAL
SEE ALSO HEART REVASCULARIZATION
SEE ALSO KIDNEY SURGERY. KIDNEY REVASCULARIZATION
P50HL-14230-07 0099 A/S SCOR-Lipids. atherosclerosis
and thrombosis - Morphological, cytochemical study of
normal and altered vasculature (mice)
P60HL-151 68-07 0005 Comprehensive sickle cell disease
center - Ophthalmology (human, rabbits, monkeys)
ROlHL-19275-03 Characterization of collateral blood
vessels (dogs)
** ROlHL-20895-03 0007 Cineangiographic studies of
cardiovascular system - Determinants of collateral
formation (dogs, hamsters)
ROlHL-20895-03 0008 Cineangiographic studies of
cardiovascular system - Intercoronary anastomotic
circulation-Stenosis and occlusion (dogs)
** ROlHL-2 19 94-01 Structure and development of
regenerating capillaries (rabbits, chick embryo)
CARDIOVASCULAR SYSTEM, BLOOD VESSELS
(GENERAL)
ROlHL-03941-18 Uterine blood flow and changes in
pregnancy (sheep)
** ROlHL-05883-18 0001 Reflex control of resistance and
capacitance vessels - Naturally occurring vasoactive
substances and the vascular neuroeffectors (dog)
** ROlHL-05883-18 0002 Reflex control of resistance and
capacitance vessels - Adenosine, adenine nucleotides and
vascular smooth muscle (dog)
** ROlHL-05883-18 0003 Reflex control of resistance and
capacitance vessels - Cardiac glycosides and sympathetic
nerve terminals in vascular smooth muscle
** ROlHL-08359-14 Morphopharmacology of vascular
adrenergic transmission (rabbits, rats)
POlHL-14985-07 0005 Adaptation to hypoxia - Control
mechanisms in the pulmonary microcirculation (animals)
POlHL-15835-06 0012 Study of muscles related to heart
disease - Contraction and energetics of visceral and
vascular smooth muscles (rabbits)
Dynamics of interstitial space in whole
Collagen synthesis by cultured human
'Excludes routine methodok)gy OR covers only general projects which preclude indexing
''Oriefited significantly to above subfect.
at the specific level.
M Grant has subproiects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
POIHl \bHVi 06 0019 'itudy ol muulet lalaled to heart
disease Vascular tmoolh muscle Electron microscopy.
eicilallon contraction (animal)
POIHl 15835 06 0025 Study ol musclts related Is heart
disease Cellular biology ol vascular tmoolh muscle
(guinea pig)
ROIHL 15852 06 Vascular ion transport and hypertensive
mechanisms
ROIHL 18015 03 Pharmacologic studies on vascular
smooth muscle (dogs, rats)
ROIHI 1925202 Vascular connective tissue Role in
atherosclerosis (rabbits)
ROIHL 20054 02 Cultured blood vessel cells
Pathophysiology (human, animals)
ROIHL 20079 02 0003 ThromboresislanI material Blood
surface interactions (human, cattle)
ROIHL 20339 02 Vascular alpha adrenergic receptor
molecular properties
POIHL 20581 01 9001 Vascular neuroeHector
mechanisms in health and disease Morphology core
ROIHL 21099 02 Subcellular changes of blood vessels in
hypertension (rats)
R01HL2128201
animals (rats)
R01HL2130302
vascular cells
R23HL 22075 01 Metabolism of arachidonic acid in blood
vessels (chickens, mammals)
ROIHL 23209 01 Autonomic receptors of the pulmonary
vasculature (mammals)
ROlHL-2321001 Biology of normal and hypertrophied
pulmonary vessels (cat. human)
ROlHL-23232-01 Effect of hypoxia on PVSM and its
precursor cells
ROlHL-23239 01 Functional characteristics of pulmonary
vascular smooth muscle (dogs)
ROlHL-23240-01 Pulmonary vascular muscle metabolism
and contractility (rats, cattle)
ROlHL-23245-01 Adrenergic receptors in pulmonary
vascular muscle (human, animal)
ROlHL-23249-01 Actin-myosin interaction in pulmonary
smooth muscle (cattle)
CARDIOVASCULAR SYSTEM, CAPILLARIES
ROlHL-03290-22 Controls of cardiac and vascular smooth
muscles (cats, rats, dogs)
** POlHL-06285-18 0152 Cardiovascular-respiratory
physiology and biochemistry - Diabetic microangiopathy by
organ and tissue culture (human)
POlHL-08805-15 0025 Regulation of ventilation and
pulmonary circulation - Pulmonary edema (rabbits)
POlHL-08805-15 0048 Regulation of ventilation and
pulmonary circulation - Permeability of alveolo-Capillary
membrane in normal pulmonary hypertensive lung
ROlHL-11152-12 Vascular physiology (human, cats, dogs)
POlHL-11414-11 0024 Thrombosis and atherosclerosis
program - Radiographic demonstration of small coronary
arteries (human, dogs)
** POlHL-11678-11 0035 Cardiovascular dynamics and their
control - Lymph flow rate and protein concentration (dogs)
POlHL-1 1678-11 0036 Cardiovascular dynamics and their
control - Pulmonary capillary dynamics and edema (dogs)
" POlHL-11678-11 0039 Cardiovascular dynamics and their
control - Capillary and interstitial fluid dynamics of the
intestine (cats)
** POlHL-11678-11 0070 Cardiovascular dynamics and their
control - Interaction of the four Starling forces (dogs)
ROlHL-12792-09 Local control of the microcirculation
(hamsters, rats)
** ROlHL-13694-08 Capillary basement membrane In
cardiovascular disease (human, rats)
** ROlHL-13901-08 Ontogeny, ultrastructure. function in
lymphatic system (birds, fish, mammals)
P50HL-14230-07 0099 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Morphological, cytochemical study of
normal and altered vasculature (mice)
POlHL-14388-07 0232 Regulation of the circulation in
pathological states - Idiopathic cyclic edema
** ROlHL-16421-08 Determinants of RBC deformability and
capillary flow (human, mice)
** ROlHL-16666-05 Micropinocytosis in isolated capillary
endothelium
ROlHL-16828-04 Gradient and transport of oxygen in
tissue and organs (mammals)
POlHL-16851-04 0003 Human red cell membrane in
health and disease - Modeling membrane mechanics and
blood rheology
ROlHL-16916-04 0002 The role of albumins in lung water
accumulation - Lung water balance-Forces, models and
albumin concentrations (rabbits, dogs)
" ROlHL-17080-05 Localization of pore systems in capillary
walls (rats, mice, rabbits)
" POlHL-17421-05 0003 Regulation and exchange in the
microcirculation - Transcapillary fluid exchange in rat
intestinal muscle, mucosa, and mesentery
ROlHL-17628-03 Pulsatile pressure-flow dynamics (dogs)
POlHL-17731-04 0001 Physiological basis of pulmonary
disease - Mechanisms of blood flow and ventilation (dogs)
ROlHL-17781-03 Hypertension, kidney disease and renal
lymph (dogs, rats)
ROlHL-17998-04 Regulatory mechanisms in blood
circulation (dogs)
(contd)
CAR
** ROlHL-18010-04 Capillary transport of large molecules
(dogs, sheep)
ROlHL-18145-03 Oxygen transport mechanisms in hypoxia
(dogs, rats, rabbits)
** POlHL-18208-04 0006 Center for the study of blood cell
rheology - Analysis of flow in arterioles and capillaries
(human)
ROlHL-18426-04 Regulation of renal hemodynamics (dogs)
ROlHL-18705-03 Regulation of plasma triglyceride
metabolism (rats)
ROlHL-18762-03 Post-traumatic pulmonary insufficiency
(dogs)
ROlHL-19053-03
(human)
R01HL19139-03
Vascular anatomy of the telencephalon
Dispersion of diffusible indicators in the
body (human, cats, dogs)
P50HL-19153-02 0004 SCOR-Pulmonary edemas-Eitology,
pathogenesis - Physical mechanisms in lung transvascular
transport -Math models (sheep)
P50HL-19153-02 0005 SCOR-Pulmonary edemas-Eitology,
pathogenesis - Lung vascular permeability measured by
indicator dilution methods (sheep)
P50HL-1915302 0006 SCOR-Pulmonary edemas-Eitology,
pathogenesis - Pulmonary vascular abnormalities in human
lung diseases
** ROlHL-19674-02 Electrolyte permeability of single
capillaries (frogs)
ROlHL-19824-02 Mass transfer in the microcirculation
ROlHL-20143 02 Hypothermic circulatory arrest -Cerebral
vascular change (dogs)
ROlHL-21096-02 Sickle cell crisis-Role of the erythrocyte
men\brane (human)
** ROlHL-21452-02 Pulmonary capillary filtration in
myocardial ishemia (dogs)
'* ROlHL-21568-02 Cell biology of the alveolar-capillary unit
(animals)
** R23HL-2 1853-01 Lung metabolism and alveolo-capillary
permeability (rats)
** R23HL-2 1943-01 Capillary morphology in pulmonary
edema (dogs)
ROlHL-21948-01 Capillary, tissue volume and lymph flow
in lung edema (sheep, cattle)
** ROlHL-21994-01 Structure and development of
regenerating capillaries (rabbits, chick embryo)
** ROlHL-22088-02 Metabolic basis for diabetic
microangiopathy (cattle)
ROlHL-221 13-02 Micro/macrovasculature in healing of
foot lesions (human)
ROlHL-22152-02 Ventricular dysfunction and cardiac
surgery (dogs)
** ROlHL-22435-02 Pulmonary alveolar-capillary permeability
characteristic (dogs)
ROlHL-2246302 Pinocytotic vesicles and pulmonary
edema (rats)
** ROlHL-22549-02 Transport across alveolar capillary
membrane (dogs)
** ROlHL-22569-02 Intestinal secretion -Capillary and tissue
forces (dogs, cats)
ROlHL-23211-01 Active normoxic pulmonary vasodilatation
(rat, dog, sheep)
CARDIOVASCULAR SYSTEM, CAPIILARY BEDS
ROlHL-03941-18 Uterine blood flow and changes in
pregnancy (sheep)
*• R01HL04512-19 Ultrastructural studies of capillary
permeability (rats, mice)
ROlHL-0580618 Analysis of antiarrhythmic agents (dogs,
rabbits)
POlHL-0629618 0002 Cardiovascular and pulmonary
adaptation to stress - Respiratory muscle blood flow,
mechanics and metabolism (human, dog)
P01HL0868215 0038 Regulation of the cardiovascular
system • Control of pulmonary circulation (dogs)
POlHL-08899 14 0080 Tolerance to respiratory gases in
health and disease - Dynamic quantitation of continuous
isobaric gas embolization
ROlHL-10622-12 Volumes and compliance of pulmonary
circulation (human, dogs)
R01HL1088113 Structure and function of
microcirculation (hamsters, rats. cats, dogs)
ROIHL 12174-11 Ventilation/perfusion distribution in the
lung (human, mammals)
** R01HL1260710 Dynamics of pulsatile blood flow (human,
dogs, rats)
ROIHL 12792-09 Local control of the microcirculation
(hamsters, rats)
** P50HL 14187-07 0015 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses -
Pathophysiologic responses of pulmonary capillary bed
(dog. human)
ROlHL-1556205 Regulation of skeletal muscle blood flow
(dogs)
ROlHL-15580-06 Humoral control of pulmonary and
systemic circulation (animals)
ROIHL 1572206 Hemorrheology studies related to in vivo
blood flow (human)
" POlHL-15832-06 0011 Chemical-structural predispositions
to lung injury ■ Interaction of cell receptors with vasoactive
agents in pulmonary vascular bed
POlHL-1583206 0012 Chemical-structural predispositions
to lung injury - Contractile structures and contractility in
cells of lung respiratory tract
128
ROlHL-163 15-05 Analysis of interaction between CNS
vasomotor systems (cats, rats)
R01HL16648-16 Integrated control of cardiovascular
activity (cats)
ROlHL-17080-05 Localization of pore systems in capillary
walls (rats, mice, rabbits)
P60HL17269-04 0023 National heart and blood vessel
research and demonstration center • Cardiovascular
pharmacology-Ischemia, shock and heart failure (dog, cat,
rat)
ROlHL-17459-03 Myocardial ischemia (dogs)
POlHL-17871-04 0009 Kidney, sodium, cardiac output.
arterioles and hypertension ■ Kidney, sodium, cardiac
output, arterioles and hypertension
ROlHL-17903-03 Regional circulatory responses to hypoxia
(rats, cats, rabbits)
R01HL-I9039-03 Circulation studies by one vs two circuit
model (dogs)
P01HL19737-02 0008 Cellular and molecular aspects of
respiratory physiology - Kinetics of movement of acid
metabolites from cell to capillary blood (dogs)
POlHL-19737-02 0010 Cellular and molecular aspects of
respiratory physiology - Effects of pulsatile flow and volume
on capillary exchanges (dogs, rats)
ROlHL-1999702 Prostaglandin precursors and intestinal
vasculature (cats, rabbits)
ROlHL-20206-02 Carbohydrates-nucleotides and adrenergic
interactions (rabbits, cats, rats)
POlHL-20581-01 0004 Vascular neuroeffector
mechanisms in health and disease • Neuroeffector
characteristics of mesenteric and pulmonary blood vessels
(rabbits)
' ROlHL-20605-02 Microvascular responses during intestinal
absorption (rats)
ROlHL-20630-03 Development of a pulsed Doppler velocity
detector (human, animals)
ROlHL-20827-02 Effects of hypertrophy on the coronary
circulation (dogs)
ROlHL-21034-01
occlusion (dogs)
POlHL-06314-17 0047
cardiovascular disease
(human, animals)
POlHL-06314-17 0054
cardiovascular disease
CAR
Immunologic mechanisms in
Role of intravascular coagulation
R23HL-21050-02
edema (rabbits)
ROlHL-227 15-01
reflexes (dogs))
ROlHL-22928-01
(sheep)
R23HL-22975-01
blood flow (dogs)
ROlHL-22977-01
Compensatory responses to arterial
Mechanisms of re-expansion pulmonary
Neural integration of the cardiovascular
Systematic study of bronchial circulation
Dynamics of autoregulation of muscle
Role of vasoconstrictor mechanisms in
heart failure (human, dogs)
ROlHL-233 12-01 Hemodynamics and vasoactivity in renal
hypertension (human, dogs)
CARDIOVASCULAR SYSTEM, DUCTUS
ARTERIOSUS EMBRYONIC
POlHL-0628518 0126 Cardiovascular-respiratory
physiology and biochemistry • Ventricular output, foramen
ovale and ductus arteriosus flows (lambs)
POlHL-06285-18 0130 Cardiovascular-respiratory
physiology and biochemistry - Ductus arteriosus-
Morphological development (human, lambs)
P50HL-142 14-07 0026 Newborn lung center for hyaline
membrane disease - Hemodynamic studies of HMD-
Prostaglandins production and blockers (lambs)
P50HL-17682-04 0021 Study of ischemic heart disease -
Prostaglandin biosynthesis in blood vessels from ischemic
myocardium (rat, sheep)
** R23HL21409-02 Perinatal control of the ductus arteriosus
(sheep)
CARDIOVASCULAR SYSTEM, ENDOTHELIUM
SEE ALSO HEART, ENDOCARDIUM
ROlHL-01803-23 0005 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Immunologic and dietary synergy in the
pathogenesis of atherosclerosis (rabbits)
R01HL01803-23 0010 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Atherosclerosis induction-Graft rejection
and hypercholesterolemia (rabbits)
ROlHL-01803-23 0015 Arteriosclerosis, glomerulonephritis.
rheumatic fever - Immunologic endothelial injury and lipid
diet atherosclerosis (rabbits, monkey)
** ROlHL-01803-23 0016 Arteriosclerosis, glomerulonephritis.
rheumatic fever - Synthesis of basement membrane
collagen by endothelial cells (human)
ROlHL-01803-23 0020 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Virus-induced arterosclerosis (chickens)
M POlHL-03 174-23 Mechanisms of acute vascular reaction
to injury
** POlHL-031 74-23 0001 Mechanisms of acute vascular
reaction to injury - Response of the vascular intima to
injury (human, rats)
POlHL-031 74-23 0005 Mechanisms of acute vascular
reaction to injury - Renal small vessel didease-Cell and
matrix response (human, mice)
** POlHL-031 74-23 0006 Mechanisms of acute vascular
reaction to injury - Atherosclerotic plaque studies using
mosaic analysis (human)
POlHL-03174-23 0011 Mechanisms of acute vascular
reaction to injury - Mutagen metabolism by artery wall in
etiology of atherosclerosis (human, animals)
P01HL031 74-23 0012 Mechanisms of acute vascular
reaction to injury - Human atherosclerotic plaque in organ
culture
Immunologic mechanisms in
Physiology of cell communications
(mice, frogs, guinea pigs)
POlHL-06314-17 0066 Immunologic mechanisms in
cardiovascular disease - Sensitization, cell-mediated
cytotoxicity, role of lymphocytes (human, mice)
POlHL-06835-17 0027 Cardiovascular disease - Studies
in thrombosis-cross-linking of fibrinogen (human)
POIHL- 10342- 13 0024 The integrated function of
respiration and circulation - Cytochrome P450 and
physiological response to hypoxia (rats)
ROlHL-1115212 Vascular physiology (human, cats, dogs)
POlHL-11414-11 0037 Thrombosis and atherosclerosis
program - Vascular intimal injury and healing (rabbits,
rats)
R01HL11775-11 Platelet mechanisms in disease (human,
primates)
ROlHL-1249410 Continuum mechanics in biophysics
(human, animals)
ROlHL-12557-09 Effects of steroids and pregnancy on
arteries and veins (guinea pigs)
R01HL12684-09 Angiotensin I and converting enzyme in
hypertension (human, primates, dogs)
ROlHL-12792-09 Local control of the iDicrocirculation
(hamsters, rats)
R01HL12869-09 Arterial metabolism, diabetes and
atherogenesis (rats, rabbits)
ROlHL-12879-09 0005 Pulmonary transport and
metabolism in vivo - Glucose transport by pulmonary
endothelium and epithelium (dogs)
ROlHL-12879-09 0011 Pulmonary transport and
metabolism in vivo - Membrane characteristics of lung
cells (human, animals)
P01HL13108-09 0013 Clinical heart transplantation ■
Cardiomyopathic lymphocyte responsiveness to cultured
endothelium
POIHL 1326207 0018 Arterial wall in atherosclerosis -
Vasoactive factors of human plasma
POlHL-13330-08 0056 Mechanical circulatory support -
Blood compatibility linings (calves)
ROlHL-13901-08 Ontogeny, ultrastructure, function in
lymphatic system (birds, fish, mammals)
ROlHL-13921-07 The lung as a metabolic organ (animals)
P50HL14147-08 0012 Specialized center of research in
thrombosis - Tissue culture study of arterial cells (human,
hamster)
P50HLi4164-07 0044 A/S SCOR-Comparative and
experimental atherosclerosis - Cell biology-atherosclerosis
project (pigeons)
P50HL-14187-07 0014 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses - Metabolism
and actions of vasoactive peptides in lung (human,
mammals)
P50HL-1421708 0050 Specialized center of research in
thrombosis - Electron microscopy section (dogs)
P50HL14217-08 0051 Specialized center of research in
thrombosis - Microcirculation section (bat. hamster)
P50HL 14230-07 A/S SCOR-Lipids, atherosclerosis and
thrombosis
P50HL14230-07 0095 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Blood platelet adherence to endothelial
smooth muscle cells, fibroblast (human)
■ P50HL-14230-07 0096 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Ultrastructural studies of endothelial cells
(human)
P50HL-14230-07 0098 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Molecular properties of factor VIII (cattle,
human, mice)
' P50HL14230-07 0099 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Morphological, cytochemical study of
normal and altered vasculature (mice)
P50HL-14230-07 9002 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Core tissue culture laboratory
P50HL-14237-07 0002 Support for arteriosclerosis center
- Interactions of lipoprotein particles with vascular surface
(human, rat)
ROlHL-1473906 The role of leukocytes in thrombotic
disease (human, dogs)
* POlHL-14985-07 0012 Adaptation to hypoxia ■ Direct
effect of hypoxia on pulmonary vascular smooth muscle
(rats, dogs)
ROlHL-1499007 Lipid transport in avian species
(chickens)
ROlHL-15270-06 Local mechanical properties of the aortic
tissue (dogs, pigs)
ROlHL-1544806 Surgical and metabolic aspects of
venous grafts, (dogs, monkeys, rabbits)
ROlHL-1564603 Lipid studies in vascular smooth muscle
cells (human, monkeys)
P01HL15832-06 0011 Chemical-structural predispositions
to lung injury ■ Interaction of cell receptors with vasoactive
agents in pulmonary vascular bed
POlHL-15835-06 0019 Study of muscles related to heart
disease - Vascular smooth muscle-Electron microscopy,
excitation contraction (animal)
* POlHL-15835-06 0025 Study of muscles related to heart
disease ■ Cellular biology of vascular smooth muscle
(guinea pig)
(contd)
•Excludes routine methodotogy OR covers onty general projects which preclude indexing at the specific level.
"Oriefited significantly to above subject
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
^m^Ua0uttaLrjfr»^xa^ -
CAR
ia«
CAR
ROIHL 167S6-04 Oalilltd chiricttrljtics ol cotontry blood
(low (horsiM dogs, calves)
ROIHl 16328 06 Mtmbrint altctrlcil propettlos ol
vascular muscia (human, animals)
POIHI 1638/04 000? Tha blood vassal and
Ihromboianasis Hoimonal ellacts on thiomboganesis
(rats, rabbits)
POIHI 1638; 04 0009 The blood vessel and
thrombaganesis Role ol pituitary gland in the
pathogenesis ol arteriosclerotic lesions (rats)
POIHI 16411 04 0003 Blood systems in coagulation and
vessel disease Molecular events involving the late stages
ot coagulation (rabbits)
ROIHL 164S403 Vascular muscle reactivity in
hypertension (human, lats)
ROIHL 16626'0S Studies ol antibodies to antihemophilic
lactois (human, rabbits)
ROIHL 166660S Micropmocytosis in isolated capillary
endothelium
ROIHL I67U OS RBC and endothelial membrane material
characteristics (human)
ROIHL 16714 OS Endothelial cell communication in
homeostasis (human, mammals)
ROIHL 1676804 The sympathetic nervous system and the
arterial wall (rabbits, pigeons)
ROIHL 16921 OS Synthetic hydrogels as blood tolerable
materials
R01HL'169S2'0S Cardiovascular pathology (rats, rabbits)
P60HL 1726904 0048 National heart and blood vessel
research and demonstration center Atherosclerosis-
Lipoproteins and the arterial wall (human)
ROIHL'17322'04 Functional characteristics of smooth
muscle isolated from lung (animals)
POIHL 17430-OS 0008 Control of coagulation • Cultures
of von Willebrand endothelial cells (pigs)
R0IHL'17SO3'03 Vascular bubbles in decompression
sickness (minipig. dog. goat)
R01HL'17S96-03 Leukocyte endothelial interactions (rats)
R01HL-17623-0S Initial events in thrombus formation on
surfaces (human, rats)
P50HL-1764604 0012 Study of ischemic heart disease
Role of microcirculation in progression of myocardial
ischemic injury (rat)
R01HL17721-04 Effect of sex hormones on vascular
connective tissue (rats)
P01HL17731-04 0002 Physiological basis of pulmonary
disease - Biomechanics of the lung (frogs, cats)
ROlHL-17747-04 Endothelial injury and regeneration (rats)
POlHL-17813-04 0008 Lung disease and the oxygenation
of blood and tissue - Pulmonary regulation of systemic
blood pressure (human, rabbits, rats)
ROlHL-17865-04 Studies on aging -Effects of sex
hormones (rats, dogs)
' ROlHL-1 7973-04 Cultured aortic endothelial cells (human.
cattle, dogs, swine)
R01HL18085-03 Neural factors in atherogenesis (squirrel
monkeys)
R01HL18473-04 Genesis of atherosclerotic lesions
(human, mules)
' ROIHL 18519-03 Albumin, endothelium and
hemocompatibility (human, dog, cattle, rabbit)
POlHL-18575-03 0001 Mechanisms of vascular changes
in hypertension ■ Arteries and resistance vessels in
hypertension (pigs, rats)
POlHL-18575-03 0006 Mechanisms of vascular changes
in hypertension - Evaluation of arterial compliance in
hypertension (human, pigs)
' P01HL-1857S-03 0012 Mechanisms of vascular changes
in hypertension - Anatomy core facility
R01HL18625-03 Organization of arterial ground substance
(cattle)
POlHL-18645-03 Biology of the artery wall and
atherosclerosis
* POlHL-18645-03 0001 Biology of the artery wall and
atherosclerosis - Primate arterial smooth muscle and
atherosclerosis
POIHL- 1864 5-03 0003 Biology of the artery wall and
atherosclerosis - Synthesis of connective tissue proteins by
smooth muscle cells (human, monkeys)
P01HL1864S-03 0004 Biology of the artery wall and
atherosclerosis - Human arterial smooth muscle cell and
lipoprotein interaction
* POlHL-18645-03 0005 Biology of the artery wall and
atherosclerosis - Effects of atherosclerosis risk factors on
endothelium of the primate
POlHL-18645-03 0006 Biology of the artery wall and
atherosclerosis - The platelet and atherosclerosis (monkeys,
baboons)
* ROIHL- 187 14-04 Cardiovascular matrix-Morphogenesis
and maturation (human, chick embryo, mammal)
* ROlHL-18826-04 Interaction of peptides and target cells
in lung (human)
I POlHL-18827-02 Platelet vessel wall interactions in
thrombogenesis
POlHL-18827-02 0001 Platelet vessel wall interactions in
thrombogenesis Role of endothelial cells in the production
of thrombi (human, cattle)
* PSOHL- 18828-03 0001 Specialized center of research in
thrombosis - Membrane biology and hemostasis (human)
* PSOHL-18828-03 0002 Specialized center of research in
thrombosis - Endothelial cell biology (human, guinea pig)
PSOHt IH878 0) 0004 SpMllllied center ot rrwarch In
thrombosis Membtini chinifl in platelet phyMulogy Role
ot complement (mice, humsn)
PSOHl 18828 03 0006 Specialized centei ot loMiich In
thrombosis Etiology and pathogenesis ol atherosclerotii
(rabbit monkey. r«l human)
PSOHL 18828 03 OOUH Sppcidli/ed cenlni ol research in
thrombosis Biochemistry, physiology Platelets and
subcellular platelet particles (human)
PSOHL 18828 03 0009 Specialiied center of research In
thrombosis Platelet formation and megakaryocyte cell
biology (guinea pig. human)
ROIHL 1896902 Arterial wall oxygenation (rabbits, dogs)
ROIHI 19001 03 Atherosclerosis in bleeder and drug
treated subjects (pigs)
ROIHL 19056 03 Blood triglycerides and lipoprotein lipase
in the lung (rats)
ROIHL 1910S 02 Detection and adherence ol fibrin
monomer complexes (human)
ROIHL 19229 02 Prostaglandins and hypertension (human.
rats. dogs, rabbits)
POIHL 19242 02 Study of vascular smooth muscle
POIHL 19242 02 0001 Study ol vascular smooth muscle
Energy metabolism and protein turnover in vascular smooth
muscle (rats)
POIHL 19242 02 0002 Study of vascular smooth muscle
Vascular smooth muscle response to serum lipoproteins
(rats)
POIHL 1924202 0003 Study of vascular smooth muscle
Vasoactive metabolites from vascular muscle and
parenchymal tissue (animal)
POlHL-19242-02 0004 Study of vascular smooth muscle -
Cyclic nucleotide metabolism in smooth muscle cultures
(human, rats)
' POlHL-19242-02 0006 Study of vascular smooth muscle -
The contractile system of vascular smooth muscle (swine,
rats)
■ P01HH9242-02 0007 Study of vascular smooth muscle -
NE release in and reactivity of vascular smooth muscle
(animals)
' POlHL-19242-02 0008 Study of vascular smooth muscle -
NE release in and reactivity of vascular smooth muscle
(rats)
' POlHL-19242 02 0009 Study of vascular smooth muscle -
Electrophysiology of vascular smooth muscle (rats, chick
embryo)
R01HL19673-03 Surgical aspects of shock and hypoxia
(dogs, monkeys, rats)
ROlHL-19721-03 Lung inflammation-Lysosomal proteases
and liposomes (human, rabbits)
POlHL-1973702 0009 Cellular and molecular aspects of
respiratory physiology - Regulation of tissue oxygen tension
and body carbon monoxide stores (human, dogs)
ROlHL-19996-02 Role of membrane proteins in platelet
function (human, rabbits)
ROlHL-20095-03 Role of lymphokines and monocytes in
lung fibrosis (human, guinea pigs, rats)
' ROlHL-20197-02 Maintenance and repair of vascular
endothelium (human, animals)
R01HL-2020101 Hypertension and vascular steroid
receptors (rats)
ROlHL-20391-03 Polydisperse LDL-Structure. metabolism
and function (human)
ROlHL-20400-03 Diabetic neuropathy and peripheral
vascular diseases (human, hamsters)
ROlHL-20542-03 Regional hemodynamics in spontaneous
hypertension (rats)
ROIHL-20564-02 Pathogenesis of peripheral arterial
disease (rats, rabbits)
POlHL-2058101 Vascular neuroeffector mechanisms in
health and disease
* POlHL-20581-01 0001 Vascular neuroeffector
mechanisms in health and disease - Vascular neuroeffector
mechanism (rabbits)
* POlHL-20581-01 0002 Vascular neuroeffector
mechanisms in health and disease - Trophic interaction
between adrenergic nerves and vascular smooth muscle
* POIHL-20581-01 0003 Vascular neuroeffector
mechanisms in health and disease - Cerebrovascular
neuroeffector characteristics (animals)
* POlHL-20581-01 0005 Vascular neuroeffector
mechanisms in health and disease Changes in the
neuroeffector mechanism in hypertension (rabbits)
POlHL-20581-01 0006 Vascular neuroeffector
mechanisms in health and disease ■ Neuroeffector
mechanism in arteries and veins in hypertension (human)
ROlHL-20878-02 Cellular aspects of lung injury (rats,
rabbits)
* ROlHL-20924-02 Atherosclerosis and arterial cell functions
(human, rabbits)
POlHL-20984-02 0004 Cellular mechanisms in cardiac
hypertrophy - Myofibril accumulation in cardiac and
vascular muscle cells in hypertrophy
I POlHL-20993-02 Population dynamics of arterial cells in
atherogenesis
* POlHL-20993-02 0001 Population dynamics of arterial
cells in atherogenesis - Arterial SMC population dynamics
in atherogenesis (swine)
POlHL-20993-02 0004 Population dynamics of arterial
cells in atherogenesis - Modifications of cholesterol balance
related to arterial cell divisions (swine)
ROIHI 21032 07 Injury wall thickntit. and arterial wall
oiygenalion Idogi rabbilt)
ROIHI 21103 01 Parametric mechanical >ludie> ol
hypertentive arteries (do|i, rati)
ROIHI 2II0S02 Organ ipecilic drugi Ctcdiovdculir and
renal effects (dogs)
R73HL 71 189 01 Regulation of pulmonary endothelial cell
activities (human, cattle)
ROIHL 71770 01 Correlation ol arterial hemodynamict and
morphology (human)
ROIHI 21303 02
vascular cells
Collagen synthesis by cultured humin
Cyclic nucleotide metabollim In viuulir
Pulmonary angiotensin converting enzyme
Mechanical interactions between ventricle
Cell biology of the alveolar capillary unit
vWagll A new vWD deficient antigen
Pulmonary angiotensin converting enzyme
Hypertension, microvascular control and
Studies of vasomotor control (rats)
Biochemistry of human platelet
R23HL 21370 07
endothelium
ROIHI 2139402
(rabbits)
R23HL 21462 02
arteries (dogs)
R01HL2156802
(animals)
R23HL2I73001
(human)
R23HL2I89401
(cattle)
R23HL21901 01
exercise (rats)
R23HL2191401
R01HL2198801
chemotaxis
ROIHL 21994 01 Structure and development of
regenerating capillaries (rabbits, chick embryo)
ROIHL 2214901 Morphologic examination of brain
parenchymal vessels (cats)
ROIHL 22216 02 Vascular mechanisms in renal
hypertension (dogs)
ROIHL 22266-01 Production of proteases by lung cells in
culture (human, rodents, rabbits, sheep)
ROlHL-22289-01 Endothelial cell mediated fibrinolysis
(rabbits)
ROIHL 2234101 Pathogenesis of atherosclerosis in rats
ROIHL 22445-01 Platelet inhibitors Effect on coronary
bypass grafts (dogs)
ROIHL 22455-01 Platelet concentration in the marginal
layer (dogs, human)
ROlHL-22486-01 Enzyme regulation in cultured arterial
cells (swine)
ROlHL-22527-01 Prostacyclin-thromboxanes in the
cardiovascular system (human, rabbits)
ROlHL-22583-02 Ultrastructural study of endothelium in
thrombosis (human)
POlHL-22602-01 0003 Pathophysiology of the
endothelium - Mechanisms of endothelial proliferation
(human, animals)
POlHL-22602-01 0004 Pathophysiology of the
endothelium - Endothelium, platelets smooth muscle and
atherosclerosis (rabbits)
POlHL-22619-01 0008 Cellular mechanisms of heart
failure - Molecular mechanisms and differential contractile
responsiveness in VSM (dogs)
R23HL-2262101 Blood cell-mediated pulmonary (human)
ROlHL-22623-01 Polyamines cellular mediators of
atherogenesis (human)
ROlHL-22738-01 Role of bioelectric potentials in platelet
adherence (bats. rats, hamsters)
ROlHL-22739-01 Evolution and progression of pediatric
atherosrierosis
ROlHL-22939-01 Human kinin and fibrinolytic systems
and renal disease (human)
R23HL-22972-01
(rats, hamsters)
■ ROlHL-22990-01
regulation (rats)
ROlHL-23114-01
(dogs, rabbits)
N01HV12054-14
cattle)
NOlHV-12060-18
Microcirculatocy function in hypotension
Angiotensin II receptors-Mechanisms of
Control of platelet aggregation in shock
Development of intimal linings (human.
Tissue cultured endothelium for vascular
prosthetic devices (human, animals)
CARDIOVASCULAR SYSTEM, ENDOTHELIUM
PERMEABILITY
SEE ALSO CEREBROVASCULAR SYSTEM. BLOOD-BRAIN
BARRIER
SEE ALSO CEREBROVASCULAR SYSTEM. BLOOD-
CEREBROSPINAL FLUID BARRIER
SEE ALSO KIDNEY FUNCTION, GLOMERUUR FILTRATION
SEE ALSO KIDNEY FUNCTION, RENAL TUBULAR TRANSPORT
SEE ALSO PREGNANCY CIRCULATION. PUCENTAL TRANSFER
SEE ALSO RESPIRATORY FUNCTION. PULMONARY DIFFUSION
ROlHL-01803-23 0011 Arteriosclerosis, glomerulonephritis,
rheumatic fever ■ Immunopathologic consequences of
cigarette smoking (human, rabbits, plants)
** ROlHL-01803-23 0014 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Regenerated endothelium on lipid
accumulation in arterial wall (rabbit)
** ROlHL-01803-23 0017 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Contractile and relaxing proteins of blood
vessels and platelets (mammals, human)
ROlHL-02363-20 Kinetics of water and electrolytes in
shock (dogs, rats)
POlHL-03174-23 0013 Mechanisms of acute vascular
reaction to injury - Surface morphology of the aorta in
normal and injured states (rats, rabbits)
(contd)
*Excludes foitine methodotogy OR covers only general projects which preclude indexing at the specific level.
**Onented signifkantly to above subject.
M Grant has subprojects describing specific research aspectS-
See Appendix for investigator's name and grant number.
CAR
Pulmonary transport and
Stop-tlow technique for permeability
ROlHl.04512-19 Ultrastructural studies of capillary
permeability (rats, mice)
POlHL-06314-17 0064 Immunologic mechanisms in
cardiovascular disease - Diabetic vascular disease (human,
rats, mice)
POlHL'06835-17 0016 Cardiovascular disease - Metabolic
interactions to polyunsaturated fatty acids in atherogenic
diet (dogs)
POlHL-06835-17 0064 Cardiovascular disease - Studies
in atherosclerosis (human, animals)
ROlHL-07835-17 Experimental hypertension and renal
circulation (rats, rabbits)
POlHL-08805-15 0025 Regulation of ventilation and
pulmonary circulation - Pulmonary edema (rabbits)
POlHL-08805'15 0048 Regulation of ventilation and
pulmonary circulation • Permeability of alveolo-Capillary
membrane in normal pulmonary hypertensive lung
ROlHL-0897714 Quantitation of flow and solute flux in
microvessels (cats, rats)
ROlHL-0915414 Central control of distribution of organ
blood flow (monkeys)
R01HL09622-14 Pathogenesis of atherosclerosis (rats)
R01HL-1088M3 Structure and function of
microcirculation (hamsters, rats, cats, dogs)
ROlHL-1 1289-12 Analysis of stress in pulsatile dynamics
P01HL11678-11 0035 Cardiovascular dynamics and their
control - Lymph flow rate and protein concentration (dogs)
P01HL-11678-U 0036 Cardiovascular dynamics and their
control - Pulmonary capillary dynamics and edema (dogs)
POlHL-11678-11 0039 Cardiovascular dynamics and their
control - Capillary and interstitial fluid dynamics of the
intestine (cats)
ROlHL-11897-11 Pathogenesis of experimental
atherosclerosis (rabbits, guinea pigs)
ROlHL-12421-10 Pathophysiology of circulatory shock
(dogs, baboons)
ROlHL-12766-09 Structure-function relation of blood
vessels (rats, monkeys)
ROlHL-12879-09 Pulmonary transport and metabolism in
vivo
' ROlHL-12879-09 0005 Pulmonary transport and
metabolism in vivo - Glucose transport by pulmonary
endothelium and epithelium (dogs)
' ROlHL-12879-09 0007 Pulmonary transport and
metabolism in vivo - Effects of temperature changes on
pulmonary transport
' ROlHL-12879-09 0008
metabolism in vivo
measurements
' ROlHL-12974-10 Tracer kinetics, flows and masses in
body organs (human, dogs)
POlHL-13262-07 0011 Arterial wall in atherosclerosis -
Role of hypertension in atherosclerosis (human, monkey,
dog)
ROlHL-13323-08 Intrarenal pressure and renal function
(human, dogs)
ROlHL-13694-08 Capillary basement membrane in
cardiovascular disease (human, rats)
* P50HL-14164-07 0031 A/S SCOR -Comparative and
experimental atherosclerosis - Changes in endothelial
permeability associated with atherosclerosis (pigeon)
* P50HL14214-07 0025 Newborn lung center for hyaline
membrane disease - Pulmonary vascular permeability and
lung water-Hyaline membrane disease (sheep)
* P50HL-14217-08 0050 Specialized center of research in
thrombosis - Electron microscopy section (dogs)
P50HL-1421807 0017 Pulmonary SCOR-Newborn lung '
center - Transvascular fluid exchange, vasoactive mediators
in RDS (sheep, cat)
* P50HL-14230-07 0094 A/S SCOR -Lipids, atherosclerosis
and thrombosis - Studies of atherosclerosis and regression
(monkeys)
POlHL-14388-07 0232 Regulation of the circulation in
pathological states - Idiopathic cyclic edema
* ROlHL-14775-08 Mechanisms of drug action in vascular
smooth muscle (dog, rabbits)
P01HL-1498507 0010 Adaptation to hypoxia - Pulmonary
mast cell (animals)
ROlHL-15593-05 Prolonged extracorporeal cardiopulmonary
support (rats, sheep, rabbits)
POlHL-15832-06 0012 Chemical-structural predispositions
to lung injury - Contractile structures and contractility in
cells of lung respiratory tract
R0IHL15852-06 Vascular ion transport and hypertensive
mechanisms
ROIHL 16094-06 The dynamics of microcirculatory function
(dogs)
* POIHL 16387-04 0003 The blood vessel and
thrombogenesis - Blood vessel healing (rabbits)
* ROlHL-164 19-03 Arterial uptake of lipoprotein -Kinetic
analysis (rabbits)
ROIHL-16588-05 Collagen synthesis in atherosclerosis
(dogs, rats, rabbits, human)
R01HL-16e43'02 Fluorocarbon emulsions as artificial
blood (animals)
ROlHL-16714-05 Endothelial cell communication in
homeostasis (human, mammals)
P01HL-ie910-05 0001 Regulation of the peripheral
circulation - Quantitative studies of microcirculatory control
(bats)
I R01HL16916-04 The role of albumins in lung water
accumulation
130
ROlHL-16916-04 0001 The role of albumins in lung water
accumulation - Capillary permeability (dogs, human)
ROlHL-16916-04 0002 The role of albumins in lung water
accumulation - Lung water balance -Forces, models and
albumin concentrations (rabbits, dogs)
ROlHL-17080-05 Localization of pore systems in capillary
walls (rats, mice, rabbits)
ROlHL-17355-04 Pulmonary vascular adjustments in
circulatory collapse (dogs, rats)
POlHL-17421-05 Regulation and exchange in the
microcirculation
POlHL-17421-05 0001 Regulation and exchange in the
microcirculation - Mass transfer and microcirculatory
function (rats)
POlHL-17421-05 0003 Regulation and exchange in the
microcirculation - Transcapillary fluid exchange in rat
intestinal muscle, mucosa, and mesentery
ROlHL-17516-04 Role of androgen as a risk factor in
atherogenesis (human, animals)
P50HL-17646-04 0012 Study of ischemic heart disease -
Role of microcirculation in progression of myocardial
ischemic injury (rat)
P50HL-1 7646-04 0013 Study of ischemic heart disease -
Maintenance of myocardial vascular integrity after
revascularization (dogs)
P50HL-17669-04 0022 Ischemic heart disease center
(SCOR) - Pathological studies of human and experimental
ischemic heart disease
ROlHL-17747-04 Endothelial injury and regeneration (rats)
ROlHL-17781-03 Hypertension, kidney disease and renal
lymph (dogs, rats)
POlHL-17812-04 0007 Thrombosis and plasma proteins -
Blood components -Response to endotoxin (dogs, baboons)
ROlHL-17964-04 The alternate pathway for fibrinolysis
(human)
ROlHL-17998-04 Regulatory mechanisms in blood
circulation (dogs)
' ROlHL-180 10-04 Capillary transport of large molecules
(dogs, sheep)
P50HL-183 18-03 0014 Pathogenesis and complications of
hypertension - Arterial metabolism and atherogenesis (rat,
rabbit)
* POlHL-18575-03 0007 Mechanisms of vascular changes
in hypertension - Microscopy of hypertensive arterial lesions
(rats)
ROlHL-18606-04 Pathogenesis and measurement of
pulmonary edema (human, rabbits, dogs)
ROlHL-18629-04 Influence of aging and hypertension on
the myocardium (rats)
POlHL-18646-03 0008 Studies basic to heart
transplantation - Immunophysiology and early detection of
rejection (dogs)
ROlHL-187 18-04
reactivity (dogs)
* ROlHL-18762-03
(dogs)
POlHL-18827-02 0002 Platelet vessel wall interactions in
thrombogenesis - Interactions of vessel wall
macromolecules with factor XII (human, rats)
P50HL- 188 28-03 0005 Specialized center of research in
thrombosis - Platelet inflammatory factors in thrombosis
(human, guinea pig)
ROlHL-18831-03 Microscopy of spontaneously hypertensive
arterial lesion (rats)
ROlHL-18866-02 Microvascular flow, volume, and
reactivity (rats, cats)
ROlHL-18952-03 Metabolism in perfused fetal and
newborn rabbit lungs
ROlHL-19048-03 Structure of baroreceptors in
hypertension (rats)
* ROlHL-19139-03 Dispersion of diffusible indicators in the
body (human, cats, dogs)
I P50HL-191 53-02 SCOR -Pulmonary edemas -Eitology,
pathogenesis
* P50HL 19153-02 0001 SCOR-Pulmonary edemas-Eitology,
pathogenesis - Prostaglandins and the lung circulation
(sheep)
* P50HL-191 53-02 0002 SCOR -Pulmonary edemas-Eitology,
pathogenesis Lung fluid dynamics-Classical mediators
and their inhibitors (sheep)
* P50HL-19153-02 0003 SCOR-Pulmonary edemas-Eitology,
pathogenesis - Possible inhibitors of mediator release and
pulmonary vascular response (sheep)
* P50HL-191 53-02 0004 SCOR-Pulmonary edemas-Eitology,
pathogenesis - Physical mechanisms in lung transvascular
transport-Math models (sheep)
'* P50HL-191 53-02 0005 SCOR -Pulmonary edemas-Eitology,
pathogenesis - Lung vascular permeability measured by
indicator dilution methods (sheep)
'* P50HL-191 53-02 0006 SCOR-Pulmonary edemas-Eitology,
pathogenesis - Pulmonary vascular abnormalities in human
lung diseases
'* P50HL-191 55-02 0002 Pathophysiology of pulmonary
edema - Non-invasive measurement of protein turnover in
human lung (also sheep)
'* P50HL-191 55-02 0005 Pathophysiology of pulmonary
edema - Protein exchange sites and lymph protein
concentration in lung (mice, sheep)
■* P50HL-191 85-02 0004 Pulmonary SCOR -Neonatal
respiratory distress syndromes - Fluid and protein transport
in fetal and newborn lung (sheep, rabbits)
Prostaglandin precursors and vascular
PosMraumatic pulmonary insufficiency
Aortic histamine synthesis in diabetes
Restoring microcirculation after platelet
Cellular aspects of lung injury (rats.
Population dynamics of arterial
Arterial endothelial dynamics in
CAR
* ROlHL-19370-03 Coronary capillary exchange-The effects
of ischemia (dogs, sheep)
* ROlHL-19454-02 Rheological factors In transport across
arterial wall (dogs)
* R01HL-1945S-03 Role of endothelial cells in vascular
permeability (tissue culture)
* ROlHL-19674-02 Electrolyte permeability of single
capillaries (frogs)
POlHL-19717-02 0007 Response of the lung to injury -
Cellular level studies of prostaglandin-like molecules
(cattle)
* ROlHL-19830-02 Shear to aortic histamine synthesis and
permeability (dogs)
* ROlHL-20054-02 Cultured blood vessel cells-
Pathophysiology (human, animals)
ROlHL-20143-02 Hypothermic circulatory arrest-Cerebral
vascular change (dogs)
ROlHL-20197-02 Maintenance and repair of vascular
endothelium (human, animals)
ROlHL-20460-03
(rat)
ROlHL-20563-02
aggregation
ROlHL-20878-02
rabbits)
■* POlHL-20993-02 0002
cells in atherogenesis
atherogenesis (swine)
" ROlHL-21188-02 Pulsatory water flux and endothelial cell
desquamation
'* ROlHL-21376-02 Blood-gas barrier solute and water
transport (rabbits)
ROlHL-21416-02 Atherosclerosis in new modles of
diabetes mellitus
** ROlHL-2 1429-02 Transport of LDL in arterial wall (human,
mammals)
** ROlHL-21438-02 Structure and permeability of arterial
endothelium (pigs)
ROlHL-21452-02 Pulmonary capillary filtration in
myocardial ishemia (dogs)
ROlHL-2 1498-02 Pathophysiology of edema (rats, cats)
** ROlHL-21525-02 Effect of cations, anions and water upon
blood vessels (dogs, rats)
ROlHL-2 1592-01 Lipoproteins and coagulation factors in
atherosclerosis (pigeons)
ROlHL-21756-11 Vascular disease-Cytochemistry and
ultrastructure (human, rats, mice, hamsters)
ROlHL-21851-01 Cerebral microcirculation In experimental
hypertension (cats, rabbits)
** R23HL-21853-01 Lung metabolism and alveolo-capillary
permeability (rats)
** R23HL-21950-01 Endothelial cell mechanisms in vascular
disease (human)
ROlHL-2 1994-01 Structure and development of
regenerating capillaries (rabbits, chick embryo)
ROlHL-22152-02 Ventricular dysfunction and cardiac
surgery (dogs)
** ROlHL-22244-01 Cardiopulmonary bypass and the
vascular endothelium (dogs)
R01HL-22327-01 Transport of arterial blood gases through
skin (swine)
** R23HL-22346-01 Hematological injury and pulmonary
dysfunction (human, mammals)
" ROlHL-22435-02 Pulmonary alveolar-capillary permeability
characteristic (dogs)
** ROlHL-22520-01 Pulmonary vascular response to group B
Streptococci (human, mammals)
ROlHL-22549-02 Transport across alveolar capillary
membrane (dogs)
M POlHL-22602-01 Pathophysiology of the endothelium
" POlHL-22602-01 0001 Pathophysiology of the
endothelium - Platelet-endothelial interactions in vitro
(human, cattle)
** POlHL-22602-01 0002 Pathophysiology of the
endothelium - Molecular charge and endothelial
permeability (rats, mice)
POlHL-22602-01 9002 Pathophysiology of the
endothelium - Core-Culture of blood vessel-Derived cells
** ROlHL-22783-01 Hemodynamic induction of intimal
fibromuscular lesion
ROlHL-22911-01 Mechanism of clearance of lung edema
fluid (dogs)
** R23HL-22933-01 Transvascular fluid and protein exchange
in the lung (sheep)
ROlHL-23015-01 Mechanisms of hypo-oncotic pulmonary
edema (human, dogs)
ROlHL-23211-01
(rat, dog, sheep)
ROlHL-23600-01
dogs, rats)
ROlHL-23603-01
disease (rats)
ROlHL-23604-01
mechanisms (rat)
ROlHL-23653-01 Protection of the ischemic myocardium
(dogs)
CARDIOVASCULAR SYSTEM,
MICROCIRCULATION
SEE ALSO CARDIOVASCULAR SYSTEM. ARTERIOLES
SEE ALSO CARDIOVASCULAR SYSTEM. CAPILURIES
SEE ALSO CARDIOVASCULAR SYSTEM. VASA VASORUM
(contdl
Active normoxic pulmonary vasodilatation
Ions, water, and hypertension (human,
Morphogenesis of hypertensive vascular
Hepatic microvascular regulatory
'Excludes routine methodotogy OR covers only general projects which preclude indexing at the specific level
"Oriented significantly to above subject.
M Grant lias subprojects describing specific research aspects.
See Appendix for Investigator's name and grant number.
CAR
ROIHl 00487 ?9 Vtsomotor Ion* and vtnoui ratuin
(human. do|]. monhayi )
ROIHl 03290 22 Contiols ol catdiac and vasculai smooth
musclas (cats. rats, dogs)
ROIHl 04SI2 19 Ulliastiuctural studias ol capillary
paimaabilily (rats. m{ce)
POIHl 04664 18 0002 Cardiovascular and lung dynamics
X ray cross section imaging ol organs (dogs)
POIHl 0628!) 18 0128 Cardiovascular rospiratory
physiology and biochtmistry Pulmonary circulation in letal
lambs in utaro
POIHl 0628S 18 0129 Caidiovascular respiratory
physiology and biochemistry Pulmonary microciiculation in
the letus and neonate (lambs)
P01HL'0628S 18 0133 Cardiovascular respiratory
physiology and biochemistry Decreased uterine blood How
and letal development (lambs)
P0IH106285 18 0136 Cardiovascular respiratory
physiology and biochemistry Fetal microcirculation in
utero (rabbits, lambs)
POIH10628S 18 0145 Cardiovascular respiratory
physiology and biochemistry Pulmonary, pleural and
systemic micrvcirculation (animals)
POIHL 06285 18 014/ Cardiovascular respiratory
physiology and biochemistry Metabolic regulation of
cerebral microcirculation (cats)
POIHL'06314 17 0064 Immunologic mechanisms in
cardiovascular disease Diabetic vascular disease (human.
rats, mice)
POIHL'06350'17 0019 Hemostasis research program
project Microcirculation (human, rats, rabbits)
P01HL.0637017 0015 Cardiopulmonary and renal
pathology research center - Pathogenesis of chemically
induced tissue injury (rats)
' ROIHI'06736 18 Biogenic-mechanical factors in
microcirculation (rats, gerbils)
RO1HL0772315 Reflex control of vascular capacitance in
shock
POlHL'08682-15 Regulation of the cardiovascular system
POIHL'08682'15 0011 Regulation of the cardiovascular
system - Histochemistry and ultrastructure of heart
innervation (dogs, ground squirrels)
POlHL'08805-15 0006 Regulation of ventilation and
pulmonary circulation - Adaptation of lungfish-Estivation
' POlHL-0880515 0048 Regulation of ventilation and
pulmonary circulation - Permeability of alveolo-Capillary
membrane in normal pulmonary hypertensive lung
P01HL0889914 0076 Tolerance to respiratory gases in
health and disease - Bubble formation during gas
counterdiffusion (hamsters)
' ROlHL-08977 14 Quantitation of flow and solute flux in
microvessels (cats, rats)
R01HL10330-11 Physiological mechanics of the heart and
arteries (dogs, rabbits, horses)
' R01HL10881-13 Structure and function of
microcirculation (hamsters, rats, cats, dogs)
' ROlHL-11152-12 Vascular physiology (human, cats, dogs)
' ROlHl-11153-12 Quantitation of flow and solute flux In
microvessels (cats, rats)
ROlHL-1 1906-11 Comparative study of heart function
(cats, rats, hedgehogs, squirrels)
ROlHL-12421-10 Pathophysiology of circulatory shock
(dogs, baboons)
* ROlHL-1249310 Bioengineering analysis of microvascular
function (cats, rabbits)
* ROlHL-1249410 Continuum mechanics in biophysics
(human, animals)
R01HL12607-10 Dynamics of pulsatile blood flow (human,
dogs, rats)
* ROlHL-12614-09 Microcirculatory control mechanisms and
hypertension (bats, rats)
* ROlHL-1277508 Cerebral microcirculation (mice)
* ROlHL-1279209 Local control of the microcirculation
(hamsters, rats)
ROlHL-12974-10 Tracer kinetics, flows and masses in
body organs (human, dogs)
ROlHL-13036-08 Coronary thrombosis-Effects on
myocardium and in vivo detection (dogs, monkeys)
P01HL-13I08-09 0003 Clinical heart transplantation ■
Endomyocardial biopsy pathology
* ROlHL-13437-09 Physical and mechanical parameters in
the microcirculation (animals)
ROlHL'13466-08 Pulmonary platelets in shock, trauma
and embolization (dogs, pigs, rats)
ROlHL'13632-08 Vascular changes in diabetes mellitus
(human)
* ROlHL-13936-06 Microvascular responses in hypertension
(human, rats)
P50HL 14136-07 0004 Pulmonary SCOR-Airways
obstructive diseases - Morphometric studies of developing
emphysema (human)
* P50HL-1421708 0051 Specialized center of research in
thrombosis - Microcirculation section (bat, hamster)
* P01HL14985-07 0005 Adaptation to hypoxia - Control
mechanisms in the pulmonary microcirculation (animals)
* ROlHL-15390-12 Regulation of blood flow in the
microcirculation
ROlHL-15655-05 Blood flow and gas exchange in placenta
and lungs (sheep) rabbits)
* ROlHL-15722-06 Hemorrheology studies related to in vivo
blood flow (human)
191
ROIHl 16094 06 The dynamics of microcirculatory lunclion
(dogs)
ROIHl 16421 08 Determinants of RBC defoimability and
capillary flow (human, mice)
ROIHl 16643 02 Fluorocarbon emulsloni is iitlllciil
blood (animals)
KOIIIl 16/14 05 Endothelial cell cuinmunicalion In
homeostasis (human, mammals)
POIHl 16851 04 0009 Human red cell membrane in
health and disease Blood cell properties in circulatory
regulation (dogs, rabbits)
POIHl 16910 05 0001 Regulation of the peripheral
circulation Quantitative studies of microcirculatory control
(bats)
ROIHl 17091 05 Anesthetics and microvascular response
to hemorrhage (rats)
POIHL 17421 05 Regulation and exchange in the
microcirculation
POIHl 17421 05 0001 Regulation and exchange in the
microcirculation Mass transfer and microcirculatory
function (rats)
POIHL 17421 05 0002 Regulation and exchange in the
microcirculation Metabolic and myogenic blood flow
regulation in microcirculation (animals)
POIHl 17421 05 0003 Regulation and exchange in the
microcirculation Transcapillary fluid exchange in rat
intestinal muscle, mucosa, and mesentery
POIHL 17421 05 0004 Regulation and exchange in the
microcirculation Localization of flow regulation in the
microcirculation (cats, human)
POIHL 17421 05 0006 Regulation and exchange in the
microcirculation Core facilities Optical instrumentation
facility
POIHL 17421 05 0007 Regulation and exchange in the
microcirculation Core facilities -Fluorometric measurement
methods for microcirculation
ROIHL 1759603 Leukocyte-endothelial interactions (rats)
' P50HL 17646-04 0012 Study of ischemic heart disease -
Role of microcirculation in progression of myocardial
ischemic injury (rat)
P50HL-17646 04 0013 Study of ischemic heart disease
Maintenance of myocardial vascular integrity after
revascularization (dogs)
' POlHL-17731-04 0001 Physiological basis of pulmonary
disease - Mechanisms of blood flow and ventilation (dogs)
POlHl-1773104 0002 Physiological basis of pulmonary
disease Biomechanics of the lung (frogs, cats)
R01HL1778103 Hypertension, kidney disease and renal
lymph (dogs, rats)
P01H117871-04 0010 Kidney, sodium, cardiac output,
arterioles and hypertension Renal prostaglandins
metabolism in hypertension (rats, dogs)
' ROlHL-1 7902-04 Mammalian renal microcirculation
(hamsters)
* ROlHL-1799804 Regulatory mechanisms in blood
circulation (dogs)
* ROlHL-18002-03 Circulatory shock, trauma and RE-system
function (rats)
ROlHL-1801204 Cellular delects in nocturnal
hemoglobinuria (human)
ROlHl-180 15-03 Pharmacologic studies on vascular
smooth muscle (dogs, rats)
R01HL18060-04 Exercise and coronary atherosclerotic
heart disease (monkeys)
* R01HL18080-03 Extrinsic control of intestinal
microcirculation (dogs)
POIHL- 182 08-04 Center for the study of blood cell
Theology
* POlHL-18208-04 0001 Center for the study of blood cell
rheology - Physiological basis of reversible erythrocyte
shape change (human, firefly)
' POIHl- 182 08-04 0003 Center for the study of blood cell
rheology Bone marrow microcirculation (rats, mice)
* POlHL-1820804 0004 Center for the study of blood cell
rheology ■ Splenic microcirculation (rats, mice)
* POIHL- 182 08-04 0005 Center for the study of blood cell
rheology - RBC deformability and capillary flow
interrelations (human, mice)
* POlHl-18208-04 0006 Center for the study of blood cell
rheology - Analysis of flow in arterioles and capillaries
(human)
* ROlHL-18292-04 Vasodilation and microvascular oxygen
delivery (dog. hamster)
P50HL-183 18-03 0007 Pathogenesis and complications of
hypertension - Humoral factors and renal function in
experimental hypertension (rats)
* P50HL-183 18-03 0015 Pathogenesis and complications of
hypertension - Cultured smooth muscle cells and
microvessel metabolism (mammals)
POlHL-18575-03 0007 Mechanisms of vascular changes
in hypertension • Microscopy of hypertensive arterial lesions
(rats)
R01HL18605-04 Pathogenesis and measurement of
pulmonary edema (human, rabbits, dogs)
ROlHL-1862904 Influence of aging and hypertension on
the myocardium (rats)
ROlHL-18530-03 Pulmonary hemodynamics in atelectasis
and hypoxia (dogs)
ROlHL-18731-02 RES stimulating materials in
experimental shock (dogs)
* R01HL18866-02 Microvascular flow, volume, and
reactivity (rats, cats)
CAR
'* HIIIHI 1893203 Brain microcirculition obitrvtd in vivii
nllei trauma (mice)
ROIHl 18948 01 Pultalatt How and circulatory aiiittanc*
(dogt. ctlvas)
P50HI 19155 02 0004 Pathophytwloiy ol pulmonary
edema Physical and chemical eflacti of muHipla
pulmonary emboli (^tleep)
P50HI 19155 02 0005 Pathophysiology ol pulmonary
edema Protein exchange sites and lymph protein
concentration in lung (mice. )heep)
P50HI 19185 02 0004 Pulmonary SCOfl Neonatal
respiratory distress syndromes Fluid and prolain transport
in fetal and newborn lung (sheep, rabbrts)
POIHl 19737 02 0004 Cellular and molecular aspects of
respiratory physiology Rapid reactions and erythrocyte
exchanges ol blood during respiratory transport
POIHl 19737 0? 0010 Cellular and molecular aspects of
respiratory physiology Elfects ol pulsatile flow and volume
on capillary exchanges (dogs, rats)
** ROIHL 19824 02 Mass transfer in the microcirculation
** ROIHL 20143 02 Hypothermic circulatory arrest Cerebral
vascular change (dogs)
ROIHL 20197 02 Maintenance and repair ol vascular
endothelium (human, animals)
ROIHL 20539-03 Blood glucose, hemoglobin Ale, and
diabetic vascular disease (human)
•* ROIHl 20563 02 Restoring microcirculation after platelet
aggregation
** ROIHL 2060502 Microvascular responses during intestinal
absorption (rats)
R13HI-2076501 Eleventh Princeton Conference on
Cerebrovascular Disease (new Jersey)
ROIHL 20869 01 Microvascular responses to ultrasound
ROIHL 20895 03 0008 Cineangiographic studies of
cardiovascular system Intercoronary anastomotic
circulation -Stenosis and occlusion (dogs)
ROIHL 20895-03 0009 Cineangiographic studies ol
cardiovascular system - Aortic changes in atheromatosis
(rabbits)
** POlHL-2101602 0013 Sickle cell anemia and other
hemoglobinopathies ■ Microcirculatory response to sickle
cell treated with antisickling agents (rats)
ROlHL-21076-02 Lung fluid, protein exchange after
hemorrhagic shock (sheep)
** R23HI 21332-02 Pulsatile regulation of flow in the
microcirculation (cats)
ROlHL-21498-02 Pathophysiology of edema (rats, cats)
ROlHL-21548-01 Pathogenesis of pulmonary
thromboembolic disease (human, mammals)
•* ROlHl-21843-01 Ischemia, diabetes and the
microcirculation (rats. cats, hamsters)
** ROlHL-2185101 Cerebral microcirculation in experimental
hypertension (cats, rabbits)
** R23HI 21901 01 Hypertension, microvascular control and
exercise (rats)
ROlHL-21994-01 Structure and development of
regenerating capillaries (rabbits, chick embryo)
ROlHL-22 11302 Micro/macrovasculature in healing of
foot lesions (human)
** ROlHL-2211802 Microcirculation in patients with diabetes
mellitus
ROlHL-2217201 Hypotension, renal ischemia and effect of
mannitol (dogs, rats)
ROlHL-2256902 Intestinal secretion-Capillary and tissue
forces (dogs, cats)
** ROlHL-2273801 Role of bioelectric potentials in platelet
adherence (bats, rats, hamsters)
** ROlHL-22741-01 Arteriovenous connections in extremity
revascularization (dogs)
** ROlHL-2291701 Microvascular pressures in the intact
beating heart (rabbits)
** R23HL-22972-01 Microcirculatory function in hypotension
(rats, hamsters)
•* ROlHl-230 15-01 Mechanisms of hypo-oncotic pulmonary
edema (human, dogs)
** ROlHl-23603-01 Morphogenesis of hypertensive vascular
disease (rats)
** ROlHL-23604-01 Hepatic microvascular regulatory
mechanisms (rat)
CARDIOVASCULAR SYSTEM, PERIPHERAL
VASCULAR SYSTEM
ROlHL-00487-29 Vasomotor tone and venous return
(human, dogs, monkeys )
R01HL03181-21 0025 Hemodynamics as applied to
surgical problems - Vascular stenosis (dogs)
ROlHL-04457-20 Cellular aspects of active transport (fish.
rabbits, anurans, turtles)
POlHL-06835-17 0059 Cardiovascular disease -
Metyrapone-induced hypertension in dog
POlHL-0729317 0054 Noninvasive cardiovascular
measurements - Detection of arterial occlusive disease
(human)
** POlHl-07293-17 0056 Non-invasive cardiovascular
measurements Peripheral vascular system software
ROlHL-07723-15 Reflex control of vascular capacitance in
shock
POlHL-08682-15 0026 Regulation of the cardiovascular
system - Hypertension-High renin vs low renin (dog)
POlHL-10436-13 0015 A multidisciplinary study of
congenital heart disease - Fetal anu neonatal
cardiovascular physiology (sheep)
R01H110942-09 Study of genetic hypertension in rats
(contd)
"Excludes routine methodokigy OR ONers only general projects which preclude indexing at the specific level.
**0nented signif icanthr to above subject.
M Grant has subprojeds describing specific research aspects.
See Appendix for investigator's name and grant number.
CAR
POlHL-1 1310-12 0067 Mechanisms of cardiovascular
disease • Cardiac performance with measured
hemodynamic variables (human)
ROlHL-12415-10 Evaluation of left ventricular function
(dogs, rabbits)
R01HL12792-09 Local control of the microcirculation
(hamsters, rats)
P01HL1310809 0022 Clinical heart transplantation -
Studies on cardiac receptors (human)
P01HL13737-07 0009 Assisted circulation - Analytical
models
P50HL14164-07 0038 A/S SCOR -Comparative and
experimental atherosclerosis - Peripheral vascular studies-
Cholesterol, lesion regression, vascular function
P01HL-U388-07 0183 Regulation of the circulation in
pathological states - Vasopressin in cardiovascular
regulation (dogs, rats)
POlHL-14388-07 0211 Regulation of the circulation In
pathological states - Choline acetyltransferase activity
(rats)
POlHL-14388-07 0213 Regulation of the circulation in
pathological states ■ Regulation of the heart and peripheral
circulation in heart failure
POlHL-144 14-07 0008 Environmental influences on
cardiorespiratory and cellular functions - Energetics of
sv»imming (human)
ROlHL-14529-07 Systems analysis of baroreflex (dogs)
R01HL15580-06 Humoral control of pulmonary and
systemic circulation (animals)
ROlHL-15694-06 Pulmonary factors in circulatory
regulation
POlHL-16910-05 Regulation of the peripheral circulation
' POlHL-16910-05 0001 Regulation of the peripheral
circulation - Quantitative studies of microcirculatory control
(bats)
POlHL-16910-05 0002 Regulation of the peripheral
circulation - Coronary circulation (dogs)
* P01HL16910-05 0005 Regulation of the peripheral
circulation ■ Control of circulation by baroreceptor and
chemoreceptor reflexes (dog. monkey)
* POlHL-16910-05 0006 Regulation of the peripheral
circulation - Regulation of blood flow distribution (baboons,
dogs)
* POlHL-16910-05 0008 Regulation of the peripheral
circulation - Circulation to bone (dogs, baboons)
ROlHL-17366-05 Mechanisms in the production of renal
hypertension (rabbits, dogs)
* P50HL-17651-04 0015 Ischemic heart disease specialized
center of research - Peripheral circulation in acute
myocardial ischemia and infarction (human)
* P50HL-17651-04 0044 Ischemic heart disease specialized
center of research - Limb blood flow after myocardial
revascularization (human)
* P50HL-17651-04 0045 Ischemic heart disease specialized
center of research - Peripheral vascular studies -
Pharmacology (dogs, human)
P50HL-17655-04 0003 Study of ischemic heart disease ■
Cardiopulmonary resuscitation (human, dog)
P50HL-1 7665-04 0012 Study of ischemic heart disease •
Myocardial ischemia -Cardiovascular performance in the
conscious baboon and dog
P50HL-17669-04 0013 Ischemic heart disease center
(SCOR) - Exercise in patients with ischemic heart disease
* ROlHL-17853-03 Peripheral circulation in heart failure
(animals)
POlHL-17871-04 0009 Kidney, sodium, cardiac output,
arterioles and hypertension - Kidney, sodium, cardiac
output, arterioles and hypertension
ROIHLI 7903-03 Regional circulatory responses to hypoxia
(rats, cats, rabbits)
ROlHL-17954-03 Narcotics and the circulation (human,
dogs, pigs, monkeys)
ROlHL-17958-04 Circulatory effects of operant
cardiovascular control (baboons)
ROIHL 18060-04 Exercise and coronary atherosclerotic
heart disease (monkeys)
ROlHL-18489-03 Hemodynamic interactions of vasoactive
chemicals (rats)
M POlHL-18575-03 Mechanisms of vascular changes in
hypertension
POlHL-18575-03 0001 Mechanisms of vascular changes
in hypertension - Arteries and resistance vessels in
hypertension (pigs, rats)
POl HI- 185 7 5-03 0002 Mechanisms of vascular changes
in hypertension - Endocrines, electrolytes, and
hemodynamics in hypertension (pigs)
POlHL-18575-03 0006 Mechanisms of vascular changes
in hypertension - Evaluation of arterial compliance in
hypertension (human, pigs)
R01HL18714-04 Cardiovascular matrix-Morphogenesis
and maturation (human, chick embryo, mammal)
ROlHL-18866-02 Microvascular flow, volume, and
reactivity (rats, cats)
•* ROlHL-18868-03 Development of vertebrate vascular
control systems (reptiles, amphibians)
POlHL-18974-03 0001 Experimental neurogenic
hypertension program - Central neural systems regulating
arterial pressure (rabbits)
POIHL 18974-03 0006 Experimental neurogenic
hypertension program - Model of sustained arterial
hypertension (cats)
132
ROlHL-18995-04 Cardiovascular determinants of
catecholamine release (dogs)
ROlHL-18997-02 Ischemic therapy in experimental
hypersplenism (rats, dogs)
ROlHL-19039-03 Circulation studies by one vs two circuit
model (dogs)
POlHL-19242-02 0006 Study of vascular smooth muscle -
The contractile system of vascular smooth muscle (swine,
rats)
ROlHL-19997-02 Prostaglandin precursors and intestinal
vasculature (cats, rabbits)
ROlHL-20381-03 Long-term study of diabetic vascular
disease (human)
ROlHL-20428-03 The juvenile diabetic heart (human)
ROlHL-20429-03 Study of effects of diabetes reactivity
(miniature pigs, rats)
ROlHL-20663-02 Regulation of skin blood flow in man
ROlHL-20678-02 Cardiovascular adaptation to stress in
disease states (dogs)
ROlHL-20685-02 Pituitary-adrenergic-ovarian vasomotor
interaction (dogs)
ROlHL-20803-02 Intra-aortic balloon pumping (dogs,
lambs, cats)
R23HL-21212-02 Alveolar macrophage function in
Pseudomonas infection (dgs)
ROlHL-21523-01
in man
ROlHL-21578-01
adolescent
ROlHL-21673-01
Hemodynamic effects of dietary sodium
Effect of exercise upon the hypertensive
Blood volume distribution in hypertension
Angiotensin, hypertension and the CNS
Pathophysiology of venous changes in
hypertension (rats, rabbits, human, dogs)
ROlHL-21893-01
(human)
ROlHL-22617-01
(sheep)
CARDIOVASCULAR SYSTEM, VASA VASORUM
P50HL-14230-07 0094 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Studies of atherosclerosis and regression
(monkeys)
ROlHL-16066-05 Studies on neurogenic control of the
circulation (human, dogs)
ROlHL-21032-02 Injury, wall thickness, and arterial wall
oxygenation (dogs, rabbits)
** R23HL-21559-01 Oxygen supply and blood flow through
aortic vasa vasorum (dogs)
CARDIOVASCULAR SYSTEM, VEINS
SEE ALSO CARDIOVASCULAR SYSTEM. ARTERIOVENOUS
ANASTOMOSIS NORMAL
SEE ALSO CEREBROVASCULAR SYSTEM. VENOUS SINUSES
INTRACRANIAL
SEE ALSO HEART VESSELS. CORONARY VEINS
SEE ALSO RESPIRATORY CIRCULATION. PULMONARY VEINS
POlHL-063 12-17 0015 Surgical cardiology - Internal
mammary artery versus saphenous vein for coronary artery
bypass (human)
** POlHL-06664-17 0042 Cardiopulmonary function in
remediable vascular disease - Physiologic studies on vein
grafts (dogs)
ROlHL-07723-15 Reflex control of vascular capacitance in
shock
ROlHL-12557-09 Effects of steroids and pregnancy on
arteries and veins (guinea pigs)
** POlHL-14388-07 0185 Regulation of the circulation in
pathological states - Reflex control of venous tone (human,
rabbits, dogs)
** ROlHL-15448-06 Surgical and metabolic aspects of
venous grafts, (dogs, monkeys, rabbits)
ROlHL-19053-03 Vascular anatomy of the telencephalon
(human)
** ROlHL-19677-03 Venous structure and function (dogs)
** POlHL-20581-01 0006 Vascular neuroeffector
mechanisms in health and disease - Neuroeffector
mechanism in arteries and veins in hypertension (human)
** ROlHL-21673-01 Pathophysiology of venous changes in
hypertension (rats, rabbits, human, dogs)
CARDIOVASCULAR SYSTEM, VEINS, VENA
CAVAE
R01HL-18764-03 Biosorbable thromboresistant surfaces
(dogs, rats, swine, human)
R01HL-20554-02 Memory-alloy-filters for venous emboli
(dogs)
** NOlHV-629 11-04 Vena cava ring tests of biomaterials in
dogs
CARDIOVASCULAR TISSUE PRESERVATION
SEE ALSO HEART PRESERVATION
** POlHL-063 12-17 0032 Surgical cardiology - Preservation
of the heart by perfusion (dogs)
POlHL-063 12-17 0033 Surgical cardiology - Studies in
cryopreservations (rats)
** POlHL-18646-03 0010 Studies basic to heart
transplantation - Development and study of a heart
preservation chamber (dogs, sheep)
ROlHL-221 10-02 Healing complications in vascular
grcfting (dogs)
NOlHV-42960-07 Development and evaluation of cardiac
prostheses (calves)
CARDIOVASCULAR TRANSPLANTATION, BLOOD
VESSELS TRANSPLANTATION
SEE ALSO HEART REVASCULARIZATION, CORONARY BYPASS
CAR
ROlHL-01803-23 0010 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Atherosclerosis induction -Graft rejection
and hypercholesterolemia (rabbits)
POlHL-04664-18 0001 Cardiovascular and lung dynamics
- X-ray projection image videodensitometry (dogs)
** POlHL-06370-17 0013 Cardiopulmonary and renal
pathology research center - Morphologic analysis of
vascular prosthesis (human, dogs)
** ROlHL-14126-17 Effect of function on grafts and implants
of collagen (dogs, monkeys)
** R01HL-14378-07 Lipemias and reconstructive cardiac
surgery (human)
** ROlHL-15448-06 Surgical and metabolic aspects of
venous grafts, (dogs, monkeys, rabbits)
POlHL-16387-04 0003 The blood vessel and
thrombogenesis - Blood vessel healing (rabbits)
** POlHL-16387-04 0006 The blood vessel and
thrombogenesis - Mechanism of delayed vessel graft failure
(dogs, rabbits)
** ROIHL- 17369-04 Arterial bypass surgery-Structure and
metabolism (monkeys)
P50HL- 18828-03 0006 Specialized center of research in
thrombosis - Etiology and pathogenesis of atherosclerosis
(rabbit, monkey, rat. human)
ROlHL-18936-02 Heart preservation and transplantation
studies (rat)
POlHL-20581-01 0002 Vascular neuroeffector
mechanisms in health and disease - Trophic interaction
between adrenergic nerves and vascular smooth muscle
CARDIOVASCULAR VISUALIZATION*
SEE ALSO CEREBROVASCULAR VISUALIZATION*
SEE ALSO HEART VISUALIZATION*
** P50HL-14147-08 0007 Specialized center of research in
thrombosis - Radioactive tracers in recognition of
intravascular coagulation (human, dogs)
** P50HL-14147-08 0016 Specialized center of research in
thrombosis - Nuclear medicine core laboratory (human,
dogs, rats, rabbits)
** ROIHL- 17993-04 0005 Ventricular dynamics from
surgically inserted markers - Cardiac dimensions and
dynamic after mitral, aortic valve surgery (human)
M ROIHL 20895-03 Cineangiographic studies of
cardiovascular system
** NOlHV-72924-04 Non-invasive detection of atherosclerotic
lesions (human, animals)
NOlHV-72929-01 Improved detection of atherosclerosis
(human, dogs)
CARDIOVASCULAR VISUALIZATION,
ANGIOGRAPHY*
** POlHL-04664-18 0011 Cardiovascular and lung dynamics
- Detection of abnormal segments of the human ventricle
by measure of asynergy
** POlHL-04664-18 0012 Cardiovascular and lung dynamics
- Quantitative single plane left ventricular angiography
(human)
POlHL-04664-18 0013 Cardiovascular and lung dynamics
- Ventricular function in coronary disease using NTG and
ventriculograms (human)
ROlHL-12711-09 Mathematical approach to cardiovascular
mechanics (human, animals)
** P50HL-14138-05 0009 Center for research on
atherosclerosis - Core angiographic-diagnostic laboratory
(human, dogs, birds)
P50HL-14138-05 0010 Center for research on
atherosclerosis - Diet and exercise as therapy in men with
premature atherosclerosis
** P50HL-14138-05 0016 Center for research on
atherosclerosis - Computer analysis of angiograms
P50HL-14187-07 0008 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses - Pulmonary
thromboembolism (dogs, human)
** POlHL-15194-07 0017 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation and
effects of arteriographic lesions on flow (human)
** POlHL-15194-07 0020 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation in
arteriographically normal arteries (human)
** POlHL-15265-05 0012 Program on surgical control of the
hypertipidemias - Central arteriography-Radiography
laboratory (human)
ROlHL-16830-05 Non-invasive determination of aortic
blood velocities (human)
** ROlHL-17591-03 Development of electromagnetic
rheoangiography (human, dogs)
P50HL-17648-04 0034 Study of ischemic heart disease -
Data management -Hemodynamic data
** P50HL-17655-04 0004 Study of ischemic heart disease ■
Coronary arteriography In survivors of acute myocardial
infarction (human)
** R01HL-I9675-02 Coronary pharmacoangiography
ROlHL-20872-02 Multidimensional echo imaging of the
ischemic heart
** ROlHL-20895-03 0009 Cineangiographic studies of
cardiovascular system - Aortic changes in atheromatosis
(rabbits)
ROlHL-21293-02 Randomized study of coronary bypass
surgery (human)
** ROlHL-22952-01 Validation of quantitative coronary
arteriography (dogs)
** NOlHV-72930-02 Atherosclerosis assessment -Angiography
and ultrasound (dogs, human)
(contd)
•Excludes routine melhodotogy OR covers only general projects which preclude indexing at the specific level.
**Onented significantly to above subject.
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name anri grant number.
CAR
CARDIOVASCULAR VISUALIZATION,
ANOIOTOMOORAPHY'
ROIHL I2/It> 10 Oyntmic midiovHCuIlt miisurtment
using ultrasound
ROIHL 2089S 03 0005 Cintangio|raphic studies at
ctrtJiovisculai system Comput«ii2ed axial tomogiaphy
Cirdiac Will motion and Inlaiction (dogs)
ROIHL 21S89 01 Radiographic contrast toxicity in
ischemic heart
CARDIOVASCULAR VISUALIZATION,
MICROANGIOGRAPHY'
ROIHL 18144 03 Preprocessor system lor cardiograms
(human)
** ROIHI 22088 02 Metabolic basis lor diabetic
microangiopathy (cattle)
CARDIOVASCULAR VISUALIZATION, ROENTGEN
VIDEODENSITOMETRY*
M POIHL 04664 18 Cardiovascular and lung dynamics
•* P01HL046S4 18 0001 Cardiovascular and lung dynamics
Xray projection image videodensitometry (dogs)
** POIHL 04664 18 0002 Cardiovascular and lung dynamics
X ray cross section imaging ot organs (dogs)
** POIHL 04664 18 0003 Cardiovascular and lung dynamics
■ Xray projection image videometry (human, dogs)
** POIHL 0466418 0004 Cardiovascular and lung dynamics
■ X-ray cross section imaging of the circulation (dogs)
** P01HL04664-18 0006 Cardiovascular and lung dynamics
■ Cross section imaging ot organ functions using emitted
radiation (dogs)
** P01HL04664-18 0008 Cardiovascular and lung dynamics
- Micrographic video imaging technique
•• P01HL0466418 0009 Cardiovascular and lung dynamics
• Biological signal and image processing techniques (dogs)
*• POlHL-0466418 0010 Cardiovascular and lung dynamics
■ Left ventricular dynamics (human)
** ROlHL-18492-03 Measurement of regional coronary flow
reserve (human, dogs)
•* ROlHL-20895-03 0001 Cineangiographic studies of
cardiovascular system - Videodensitometry and valvular
regurgitation (human, dogs)
** ROlHL-20895-03 0003 Cineangiographic studies of
cardiovascular system • Densitometry in coronary stenosis
(human)
CARDIOVASCULAR VISUALIZATION,
VENOGRAPHY (GENERAL)*
ROlHL-22852-01 Diagnostic techniques in venous
thromboembolism (human)
CARNITINE
SEE AMMONIUM QUATERNARY, BETAINE COMPOUNDS,
CARNITINE
CAROTENE OXIDASE
SEE OXYGENASES, LIPOXYGENASE
CAROTENOIDS
SEE TERRENES. CAROTENOIDS
CAROTID ARTERIES
SEE CEREBROVASCULAR SYSTEM, CAROTID ARTERIES
CAROTID BODY
SEE NERVOUS SYSTEM, PARAGANGLIA, CAROTID BODY
CAROTID SINUS
SEE CEREBROVASCUUR SYSTEM, CAROTID SINUS
CAROTID SUNUS NERVE STIMULATORS
SEE HEART PACEMAKERS ELECTRONIC, CAROTID
STIMULATORS
CARRIER MEDIATED PERMEATION
SEE BIOLOGICAL TRANSPORT, ACTIVE TRANSPORT, CARRIER
MEDIATED PERMEATION
CARRIER PROTEINS
SEE BIOLOGICAL TRANSPORT, TRANSPORT PROTEINS (SEE
ALSO SPECIFICS)
CARRIER STATE (COMMUNICABLE DISEASE)
SEE COMMUNICABLE DISEASE TRANSMISSION, CARRIER
STATE (COMMUNICABLE DISEASE)
CARTILAGE
SEE SKELETAL SYSTEM, CARTIUGE
CARTILAGE CIRCULATION
SEE SKELETAL SYSTEM CIRCULATION
CASE FINDING
SEE HEALTH CARE SERVICES, CASE FINDING AND OUTREACH
CASE HISTORY
SEE HEALTH RECORDS, CASE HISTORY
CAT
SEE RADIOGRAPHY, SCANNING, CAT*
CATALASE
SEE PEROXIDASES, CATALASE
CATALYSTS
SEE CHEMICAL REACTIONS. CATALYSTS
Noninvasive measurement of cardiac
Quantitative radiocardiography (human.
Fabrication of grafted hydrogel coatings
133
CATAPRES
Sll IMIHA/OliS. CAIAPRfS
CATARACT
Sll (Yl OISORDIRS. (INS OlSORDfRS, CAIARACI
CATARRHINES
S(l MAMMAIS. PRIMATtS. MONKEYS AND APES
(ANIHROPOIDS, NON HUMAN). OLD WORLD MONKEYS
(CAIARRHINFS)*
CATECHOIAMINE-ASSOCIATED HYPERTENSION
Stt CARDIOVASCULAR DISOROfRS, HYPfRICNSION
(SYSTEMIC), CATECHOUMINE ASSOCIATED
CATECHOLAMINES
Srr PHfNYLAlKYUMINES, CAIECHOIAMINES
CATECHOLAMINES INHIBITORS
SEE PHFNYIALKYUMINES, CATECHOLAMINES INHIBITORS
CATECHOL O-METHYl TRANSFERASE
SEE TRANSMETHYUSES, CATECHOL 0 METHYL TRANSFERASE
CATECHOL OXIDASE
SEE OXYGENASES, MONOPHENOL MONOOXYGENASE
CATHARTICS
SEE GASTROINTESTINAL AGENTS, LAXATIVES
CATHEPSIN B
SEE PROTEASES AND PEPTIDASES, CATHEPSIN B
CATHEPSINS
SEE PROTEASES AND PEPTIDASES, CATHEPSINS
CATHETERIZATION
SEE ALSO CANNULATION
SEE ALSO CARDIOVASCULAR DISORDERS DIAGNOSIS,
CATHETERIZATION*
SEE ALSO HEART DISORDERS DIAGNOSIS, HEART
CATHCTERIZATION*
P01HL0637O 17 0016 Cardiopulmonary and renal
pathology research center ■ Endocarditis with pulmonary
arterv catheters (dogs)
R01HL22326-01
output (dogs)
ROlHL-23983-01
dogs)
NOlHV-1201745
for plastic heart assist devices
CATION
SEE IONS. CATION
CATTLE
SEE MAMMALS, ARTIODACTYLA. CAHLE*
CAUCASIAN RACE
SEE SOCIAL GROUPS, RACIAL STOCKS, WHITE RACE
CAUDATE NUCLEUS
SEE BRAIN, BASAL GANGLIA. CAUDATE NUCLEUS
CAVIA
SEE MAMMALS. RODENTS, HYSTRICOMORPHA, GUINEA PIGS*
CCA (VIRUS)
SEE VIRUSES, MYXOVIRUSES, RESPIRATORY SYNCYTIAL
VIRUSES
CEBUS
SEE MAMMALS, PRIMATES, MONKEYS AND APES
(ANTHROPOIDS, NON-HUMAN), NEW WORLD MONKEYS
(PLATYRHINES)*
CELL ADHESION
SEE ALSO CELL-CELL INTERACTION, CELL AGGREGATION
ROlHL-09125-14 Ultrastructural cytochemistry (human,
chick)
POlHL-13738-08 0004 Cardiac assist devices and
artificial hearts - Hematological evaluation of prosthetic
materials (calves)
P50HL-U147-08 0012 Specialized center of research in
thrombosis - Tissue culture study of arterial cells (human,
hamster)
P50HL-142 17-08 0050 Specialized center of research in
thrombosis - Electron microscopy section (dogs)
P50HL-14217-08 0051 Specialized center of research in
thrombosis - Microcirculation section (bat, hamster)
** P50HL-14230-07 0095 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Blood platelet adherence to endothelial
smooth muscle cells, fibroblast (human)
ROlHL-14739-06 The role of leukocytes in thrombotic
disease (human, dogs)
POlHL-151 95-04 0002 Program project in biological
materials - Structural and surface characterization
POlHL-1519504 0004 Program project in biological
materials - Biological evaluation and surface interaction
studies (dogs)
ROlHL-15230-05 Molecular basis of V Willebrand's disease
and hemophilia (human, cattle)
ROlHL-15593-05 Prolonged extracorporeal cardiopulmonary
support (rats, sheep, rabbits)
ROlHL-1671105 RBC and endothelial membrane material
characteristics (human)
ROlHL-16952-05 Cardiovascular pathology (rats, rabbits)
CEl
HOIHI 1/43/03 Pertuiion lung' Role ot tfiumilioO
Inukorylat Idogt, humtn)
'* ROIHI l/'>?503 MoUcular bttit of colUgen plildet
inlri^dion (humtn, ral)
RUIHI 1/59603 Leukocyte endothelial intericliont (rdtl
ROIHI \lhnO'j Initial avenii in Ihrombui formation on
•.urfacc. (human, rnlj)
*• ROIHI 1/930 03 Platelet membrane (unction Ananmenl
and application (animals)
ROIHI 18030 04 The role of contractile protetnt in
platelets (human rabbits)
ROIHI 18519 03 Albumin, endothelium and
hemocompatibihty (human, dog, caMIe, rabbit)
P50HI 18828 03 0009 Specialized center of research In
thrombosis Platelet formation and megakaryocyte cell
biology (guinea pig, human)
** ROIHL 19105 02 Detection and adherence of fibrin
monomer complexes (human)
ROIHI 19173 03 Analysis of blood trauma from
microporous oxygenators (human, dogs, rabbits)
*• ROIHL 1941903 Cellular interactions with foreign
materials (mammals)
ROIHL 19725 03 Complement induced pulmonary injury
(dogs, rabbits, sheep)
ROIHI 20251 02 A novel approach to nonthrombogenic
polymer surfaces (sheep, cattle)
ROIHL 2041 103 Platelet fatty acid metabolism in
diabetes (rat. rabbit, guinea pig)
ROIHL 20675 02 Alveolar macrophage function in man
R23HL 21805 01 Tissue cell interactions with vascular
prostheses (human, rats, mice)
ROlHL-22081 20 The mechanism of collagen formation
(human, cattle)
ROIHL 22338 01 Platelet adhesion and aggregation in a
flow chamber (human)
ROIHL 22583-02 Ultrastructural study of endothelium in
thrombosis (human)
** ROlHL-22585-01 Plasma proteins adsorbed to artificial
organs (human, rabbits)
R01HL-2389901
interfaces
N01HV32953 10
CELL AGE
ROlHL-10018-11
culture (rats)
ROlHL-13237-09
(human, animals)
P60HL-15157-07 0012 Comprehensive center for sickle
cell disease - Sickling and intracellular pH (human)
P60HL 1600806 0017 Wayne State University
comprehensive sickle cell center - Oxygen transport kinetics
of pre- and post-sickling cells (human)
ROlHL-16330-06 Aging-tissue injury and repair (rats)
M POlHL-16833 04 Hemoglobin and red cell system in
hemoglobinopathies
POlHL-16833-04 0011 Hemoglobin and red cell system in
hemoglobinopathies - Relationship between hemoglobin and
RBC membrane in sickling cells (human, rats)
POlHL-16851-04 0001 Human red cell membrane in
health and disease - Rheology of erythrocyte membrane
Flow and flexing at blood/biomaterial
Materials compatible with blood (dogs)
Effect of aging on beating heart cells in
Erythrocytes during early development
(human, amphiuma)
POlHL-1685104 0005
health and disease
Human red cell membrane in
Relation of hemoglobin species to
membrane properties (human)
ROlHL-1788115 Biosynthesis and degradation of blood
group substances (human, animals)
P01HL-18208-04 0001 Center for the study of blood cell
rheology - Physiological basis of reversible erythrocyte
shape change (human, firefly)
POlHL-18208-04 0005 Center for the study of blood cell
rheology - RBC deformability and capillary flow
interrelations (human, mice)
POlHL-18208-04 0007 Center for the study of blood cell
rheology - RBC membrane protein (human)
** ROIHL- 18284-04 Aging erythrocytes -Bio-recognition and
elimination (monkeys)
ROlHL-19946-03 Reduction of iron overioad in
thalassemia (children, rabbits, dogs, monkeys)
ROlHL-19996-02 Role of membrane proteins in platelet
function (human, rabbits)
R23HL-21950-01 Endothelial cell mechanisms in vascular
disease (human)
** ROlHL-22671-01 Removal of senescent and stored human
red cells
CELL AGGREGATION
SEE CELL-CELL INTERACTION. CELL AGGREGATION
CELL ANALYZERS-SEPARATORS
SEE CELL SORTING
CELL BIOLOGY (GENERAL) SEE ALSO CELL..,
CYTO..*
POlHL-06314-17 0052 Immunologic mechanisms in
cardiovascular disease - Role of cyclic nucleotides in
neutrophil function (human)
** POlHL-06314-17 0055 Immunologic mechanisms in
cardiovascular disease - Genetics and cell biology
ROlHL-12766-09 Structure-function relation of blood
vessels (rats, monkeys)
(contd)
•Excludes routine methodokjgy OR covers only general projects whicli preclude
**Onefited significantly to above subject.
indexing at the specific level.
M Grant has subprajects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
CEL
134
CEL
P50HL-1A164-07 0044 A/S SCOR-Comparative and
experimental atherosclerosis - Cell biology-atherosclerosis
project (pigeons)
P01HL16137-05 0013 Alveolar biology - Development and
pathology of surlactant-Formation of alveolar (rabbits,
sheep)
R01HL18284-04 Aging erythrocytes-Bio-recognition and
elimination (monkeys)
** ROlHL-19010-03 Metabolism and cell biology of lung
surfactant system (rabbits, sheep)
M POlHL-20592-02 Cell biology of cardiac and skeletal
muscle
POlHL-20592-02 0003 Cell biology of cardiac and
skeletal muscle - Cellular magnesium and anion activities
in ion-specific microelectrodes (frogs)
** POlHL-20592-02 0004 Cell biology of cardiac and
skeletal muscle - Excitation, conduction and contraction-
Modelling in Purkinje fibers
*• POlHL-20592-02 0005 Cell biology of cardiac and
skeletal muscle - Quantitative vortage studies
** POlHL-20592-02 0006 Cell biology of cardiac and
skeletal muscle - Permeability and ultrastructure of cardiac
nexuses (rabbits, cattle, rats)
** POlHL-20592-02 0010 Cell biology of cardiac and
skeletal muscle - Mitochondrial genesis during myocardial
cell hypertrophy and hyperplasia (rats)
*• POlHL-20592-02 0011 Cell biology of cardiac and
skeletal muscle - Myosin and cytochrome oxidase
messenger RNAs (chicken)
ROlHL-20643-02 Analysis of heart cell contraction (rats)
ROlHL-20666-02 Cell biology of platelet preservation
(human)
ROlHL-2 1140-01 Studies of pulmonay alveolar
macrophage function (rabbits)
** ROlHL-21568-02 Cell biology of the alveolar-capillary unit
(animals)
** POlHL-22602-01 0003 Pathophysiology of the
endothelium - Mechanisms of endothelial proliferation
(human, animals)
** ROlHL-22729-01 Intracellular degradation of newly
synthesized collagen (human, chick, rabbit)
CEU BIOLOGY STUDY SECTION
** ROlHL-01770-26 Structural aspects of lung surfactant
system (rats)
** ROlHL-04512-19 Ultrastructural studies of capillary
permeability (rats, mice)
** ROlHL-16507-04 Heart cell interactions and cell junction
biogenesis (mice, rats, rabbits)
** ROlHL-19148-03 Myocardial organelle lipid structure and
function (dog, rat)
** ROlHL-20902-02 Studies on marginal band system of
erythrocytes (amphibians, reptiles, fish)
** ROlHL-22560-02 Structure and motion of cilia
(Tetrahymena, mussels)
** ROlHL-23010-01 Control and mechanism of platelet
aggregation (human)
** ROlHL-23013-01 Smooth muscle development in vitro
(chick embryo)
CEU CAPSULE
SEE CELL COMPONENTS, CELL CAPSULE
CEU-CELL INTERACTION
SEE ALSO CELL FUSION (GENERAL)
SEE ALSO CELL GROWTH REGULATION, CONTACT INHIBITION
** POlHL-06314-17 0050 Immunologic mechanisms in
cardiovascular disease - Physiologic changes in
lymphocytes (human, mice)
POlHL-06314-17 0066 Immunologic mechanisms in
cardiovascular disease - Sensitization, cell-mediated
cytotoxicity, role of lymphocytes (human, mice)
POlHL-06314-17 0067 Immunologic mechanisms in
cardiovascular disease - Mitogenic and antigenic activation
of lymphocyte sub-populations
ROlHL-07652-14 Destruction of red blood cells in
hemolytic anemias (human, guinea pigs)
*• P50HL-14230-07 0096 A/S SCOR-Lipids. atherosclerosis
and thrombosis - Ultrastructural studies of endothelial cells
(human)
** ROIHL 15226-06 Interaction of blood cells with fibrinogen
and fibrin (human, animals)
POlHL-16117-05 Ion movements and membranes in
cardiovascular control
POlHL-164 11-04 Blood systems in coagulation and vessel
disease
POlHL-16411-04 0003 Blood systems in coagulation and
vessel disease Molecular events involving the late stages
of coagulation (rabbits)
ROIHL 16507-04 Heart cell interactions and cell junction
biogenesis (mice, rats, rabbits)
ROIHL-16634-13 Regulation of metabolism in fibroblasts
and platelets (human, rabbits, sheep)
ROlHL-16711-05 RBC and endothelial membrane material
characteristics (human)
ROlHL-16714-05 Endothelial cell communication in
homeostasis (human, mammals)
P01HL-I6833-04 0009 Hemoglobin and red cell system in
hemoglobinopathies - Rheological studies of sickled cells
M
M
ROlHL-17973-04 Cultured aortic endothelial cells (human,
cattle, dogs, swine)
ROlHL-18584-03 Effects of physical forces on platelets
(human)
POlHL-18708-03 0007 Oxygen, energy and contractility in
cardiac tissue - Surfaces, energy requirements, and
contractile proteins of cardiac cell in vitro
ROlHL-18826-04 Interaction of peptides and target cells
in lung (human)
POlHL-18827-02 Platelet vessel wall interactions in
thrombogenesis
POlHL-18827-02 0001 Platelet vessel wall interactions in
thrombogenesis - Role of endothelial cells in the production
of thrombi (human, cattle)
POlHL-18827-02 0003 Platelet vessel wall interactions in
thrombogenesis - Tumor cell and platelets in
thrombogenesis and metastasis (human, animals)
POlHL-18827-02 0006 Platelet vessel wall interactions in
thrombogenesis - Platelet immune injury in man
P50HL-18828-03 0002 Specialized center of research in
thrombosis - Endothelial cell biology (human, guinea pig)
ROlHL-19055-03 Platelet function during extracorporeal
perfusion (human, mammals)
P50HL-19171-02 0008 Pulmonary SCOR-Lung injury by
childhood infections Host-parasite interaction-Electron
microscopy, radioautography, histochemistry
P50HL-19 171-02 0009 Pulmonary SCOR-Lung injury by
childhood infections - Host-parasite interaction-Scanning
electron microscopy, freeze-fracture methods
P50HL-191 71-02 0010 Pulmonary SCOR-Lung injury by
childhood infections - Metabolic pathways of normal and
injured respiratory cells
POlHL-19242-02 0009 Study of vascular smooth muscle -
Electrophysiology of vascular smooth muscle (rats, chick
embryo)
ROlHL-194 19-03 Cellular interactions with foreign
materials (mammals)
ROlHL-19996-02 Role of membrane proteins in platelet
function (human, rabbits)
ROlHL-20104-03 Pulmonary granulomatous inflammations
(mice)
ROlHL-20132-03 Histogenesis and biochemistry of
embryonic lung (birds)
' R23HL-21805-01 Tissue cell interactions with vascular
prostheses (human, rats, mice)
ROlHL-21988-01
chemotaxis
' ROlHL-22235-01
(rabbits)
ROlHL-22583-02 Ultrastructural study of endothelium In
thrombosis (human)
POIHL 22602-01 Pathophysiology of the endothelium
** POlHL-22602-01 0001 Pathophysiology of the
endothelium - Platelet-endothelial interactions in vitro
(human, cattle)
** POlHL-22602-01 0004 Pathophysiology of the
endothelium - Endothelium, platelets smooth muscle and
atherosclerosis (rabbits)
R23HL-22621-01 Blood cell-mediated pulmonary (human)
ROlHL-22738-01 Role of bioelectric potentials in platelet
adherence (bats, rats, hamsters)
** ROlHL-22883-01 Lung epithelial cell interactions in vitro
** ROlHL-230 10-01 Control and mechanism of platelet
aggregation (human)
NOlHV-42969-06 Interactions of natural and chemically
modified biopolymers with blood (dogs)
NOlHV-42984-05 Interactions of modified biopolymers with
blood (humans, rats)
** NOlHV-52907-04 Interactions of platelets with collagens
(human, mammals)
CELL-CELL INTERACTION, CELL AGGREGATION
SEE ALSO BLOOD PLATELETS, PUTELET AGGREGATION
SEE ALSO CELL ADHESION
ROlHL-05168-19 Inhomogencity of hemoglobin types
(human)
POlHL-1 13 10-12 0097 Mechanisms of cardiovascular
disease - Structural-functional relationships of neuronal
differential alloantigens (mice)
ROlHL-13036-08 Coronary thrombosis-Effects on
myocardium and in vivo detection (dogs, monkeys)
POlHL-13737-07 0026 Assisted circulation - Hemostatic
mechanism (human, dogs)
ROlHL-163 75-04 Investigation of hemoglobin S properties
(human)
POlHL-164 11-04 0004 Blood systems in coagulation and
vessel disease - Platelets reactions in vascular injury
(human, animals)
POlHL-164 11-04 0006 Blood systems in coagulation and
vessel disease - Factor Vll-lmmunochemistry and
Immunoblology (human, mice)
POlHL-16851-04 0003 Human red cell membrane in
health and disease - Modeling membrane mechanics and
Biochemistry of human platelet
Mechanism of cardiac pacemaking
M
blood rheology
POlHL-16851-04 0006
health and disease
(human)
POlHL-16851-04 0011
health and disease -
Human red cell membrane in
Ultrastructure laboratory -Core facility
Human red cell membrane in
Hexose transport and erythrocyte
membrane proteins (human)
POlHL-16851-04 0008 Human red cell membrane in
health and disease - Force balance in red cell interactions
(human)
POlHL-18208-04 0007 Center for the study of blood cell
rheology - RBC membrane protein (human)
ROlHL-21217-01 Ion and 5-hydroxytfyptamine transport by
platelets
ROlHL-22239-01 The molecular basis of electrical
excitability (chick embryos, rats)
ROlHL-22883-01 Lung epithelial cell interactions in vitro
CELL-CELL INTERACTION, INTERCELLULAR
CONNECTIONS-JUNCTIONS
SEE ALSO NERVOUS SYSTEM. NERVE ENDINGS. SYNAPSES
SEE ALSO NEUROMOTOR SYSTEM. NEUROMUSCUUR
JUNCTION
ROlHL-0 17 70-26 Structural aspects of lung surfactant
system (rats)
POlHL-03174-23 0001 Mechanisms of acute vascular
reaction to injury - Response of the vascular intima to
injury (human, rats)
** ROlHL-04512-19 Ultrastructural studies of capillary
permeability (rats, mice)
** POlHL-06285-18 0212 Cardiovascular-respiratory
physiology and biochemistry - Membrane structure and
function-Gap junction (bovine)
** POlHL-06314-17 0054 Immunologic mechanisms in
cardiovascular disease - Physiology of cell communications
(mice, frogs, guinea pigs)
ROlHL-09125-14 Ultrastructural cytochemistry (human,
chick)
ROlHL-10897-12 Effects of hormones on cardiac
electrogenesis (rabbits, guinea pigs, dogs)
ROlHL-12486-10 Structure-function correlation in the
atrium (rabbits)
Physiologic pharmacology and its
Myocardial cells in tissue culture
POlHL-12738-10 0135
clinical applications
(rats, chick embryo)
** POlHL-161 17-05 0001 Ion movements and membranes in
cardiovascular control - Developmental studies of
contractile cell junctions (rats, rabbits, elasmobranch)
** ROlHL-16328-06 Membrane electrical properties of
vascular muscle (human, animals)
ROlHL-16507-04 Heart cell interactions and cell junction
biogenesis (mice, rats, rabbits)
ROlHL-16714-05 Endothelial cell communication in
homeostasis (human, mammals)
ROlHL-17080-05 Localization of pore systems in capillary
walls (rats, mice, rabbits)
ROlHL-17581-03 Patent ductus arteriosus and pulmonary
hypertension (dogs)
ROIHL- 17 596-03 Leukocyte-endothelial interactions (rats)
P50HL-17648-04 0031 Study of ischemic heart disease -
Ultrastructural consequences of myocardial ischemia (rat)
ROlHL-18631-03 Ultrastructural correlates of myocardial
ischemia (rats, swine)
POlHL-19737-02 0002 Cellular and molecular aspects of
respiratory physiology - Airway smooth muscle In health
and disease (human, animals)
POlHL-20592-02 0006 Cell biology of cardiac and
skeletal muscle - Permeability and ultrastructure of cardiac
nexuses (rabbits, cattle, rats)
R23HL-21853-01 Lung metabolism and alveolo-caplllary
permeability (rats)
** ROlHL-22924-01 The airway mucosal barrier (guinea pigs)
CEU CHEMOTAXIS
SEE ENVIRONMENT. ORIENTATION. CHEMOTAXIS
CELL COMMUNICATIONS
SEE CELL-CELL INTERACTION
CELL COMPONENTS
SEE ALSO CELL FLUIDS
SEE ALSO GENETICS, CHROMOSOMES
SEE ALSO GENCTICS, GENES
SEE ALSO MUSCLE CELLS, SARCOMERES
SEE ALSO MUSCLE CELLS. SARCOSOMES
SEE ALSO MUSCLES, MYOFIBRILS
SEE ALSO NERVOUS SYSTEM, NEURONS, AXONS
ROlHL-15002-07 Biochemical pharmacology of guanylate
cyclase in lung (cattle, rats)
** POlHL-15832-06 0012 Chemical-structural predispositions
to lung injury - Contractile structures and contractility in
cells of lung respiratory tract
POlHL-15835-06 0021 Study of muscles related to heart
disease - Fast kinetic studies in muscle subcellular
organelles (animals)
ROlHL-16710-03 Myocardial subcellular localization of
calcium (dogs)
ROlHL-18077-04 Smooth muscle cell organization and
Ca20 concentration control (chickens)
ROlHL-18824-03 Mechanisms of heart failure in
myopathic hamster
ROlHL-19072-03 Modification of tissue Injury in
myocardial infarction (dogs, human)
ROlHL-19673-03 Surgical aspects of shock and hypoxia
(dogs, monkeys, rats)
** ROlHL-20718-02 Microstructural integrity of stored human
platelets
R23HL-21413-02 Structure and function of platelet
calcium-binding protein (human)
CELL COMPONENTS, CELL CAPSULE
ROlHL-03919-20 The cell suface of streptococci (rats,
human)
(contd)
I
i
txdudes iDutine melhodofcxy OR covers only general projects which preclude indexir\g at the specific level.
"Granted significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
CEU COMPONfNTS, CEIL MEMBRANE
Sff Also BLOOD (HfMAIOlOr.lC) KSIS, OSMOTIC
FRACIUTV
SEE ALSO CELL COMPONENTS. INTRACELLULAR MEMBRANES
SEE ALSO CELL COMPONENTS LIPOSOMES
SEE ALSO CELL COMPONENTS, MIIOCHONORIAl MfMBRANE
SEE ALSO CELL COMPONENTS, NUCLIAR MiMBRANE
SEE ALSO MEMBRANE, ERYTHROCYTE GHOST AND
MEMBRANE
SEE ALSO MEMBRANE SURFACE (BIOLOGICAL) ACTIVITY
(GENERAL)
SEE ALSO PROTEINS. MEMBRANE PROTEINS
ROIHL 00082 30 Transmembiane movements (barnacles,
tiois. tats)
ROIHL 01/?0 26 Stiuctural aspects ol lung surtactant
system (rats)
R01HL01803 23 0001 Arteriosclerosis, glomeruloneptiritis,
rl)eumatic tever Post streptococcal glomerulonephritis
(rabbit)
ROIHI 01974-24 Ion pump in the erythrocyte (rabbits,
guinea pigs)
ROIHL 02063 23 Biochemistry and function ol lipids and
cell membranes (human, yeast, animals)
P01HL03174 23 0009 Mechanisms o( acute vascular
reaction to injury Mast cell lipid interaction (human, rats)
** R01HL03919 20 The cell sutace ot streptococci (rats,
human)
ROIHL 04457-20 Cellular aspects of active transport (fish,
rabbits, anurans. turtles)
ROlHL-04512 19 Ultrastructural studies ot capillary
permeability (rats, mice)
ROIHL 05949-18 Biochemistry of muscle contraction (rats,
rabbits)
** PO1HL06285-18 0196 Cardiovascular-respiratory
physiology and biochemistry - Hormonal regulation of
sodium transport-Epithelial cell membranes (toads)
PO1HL06285-18 0207 Cardiovascular-respiratory
physiology and biochemistry Feedback control of
cholesterol synthesis in non-hepatic tissues (animals)
** POlHL-06285 18 0211 Cardiovascular-respiratory
physiology and biochemistry - Purple membrane of
Halobacteria
** POlHL-06285-18 0212 Cardiovascular-respiratory
physiology and biochemistry - Membrane structure and
function-Gap junction (bovine)
POlHL-06285-18 0213 Cardiovascular-respiratory
physiology and biochemistry - Membrane structure and
function-Gas vacuole membrane (Halobacterium)
** P01HL06285-18 0214 Cardiovascular-respiratory
physiology and biochemistry - Membrane structure and
function-EM of macromolecules
POlHL-06314-17 0051 Immunologic mechanisms in
cardiovascular disease - Conformational studies of
phospholipid membranes and proteins
POlHL-06370-17 0006 Cardiopulmonary and renal
pathology research center - Chemical basis of
ultrastructural changes in disease (rats)
POlHL-06835-17 0018 Cardiovascular disease - Fatty
acid concentration (rats)
POlHL-06835-17 0019 Cardiovascular disease - Fatty
acid distribution (rats)
** ROlHL-07449-17 Formation and survival of red blood cells
(human)
R01HL-07652-14 Destruction of red blood cells in
hemolytic anemias (human, guinea pigs)
PO1HL-09O11-15 0015 A research and resource program
in blood - Regulation of synthesis and transport of diverse
proteins in liver (rats)
POlHL-09011-15 0019 A research and resource program
in blood • The transport mechanism of raRNA (rat, yeast,
ascites cells)
ROlHL-09610-14 Control of cholesterol metabolism-Bile
acid transport
M ROlHL-09906-13
blood cells
ROlHL-09906 13 0020 Membrane transport processes in
red blood cells - Calibration of a fluorescent probe for
erythrocytes
ROlHL-09906-13 0021 Membrane transport processes in
red blood cells - Membrane potentials in human red blood
cells due to proton gradients
ROlHL-09906-13 0022 Membrane transport processes in
red blood cells - Anion transport in dog and cat red cells
ROlHL-09906-13 0023 Membrane transport processes in
red blood cells - Cation and anion movements In two sub-
groups of dog erythrocytes
ROlHL-09906-13 0024 Membrane transport processes in
red blood cells - Inhibition of sulfate transport in human
RBCs by isothiocyanic acid esters
ROlHL-09906-13 0025 Membrane transport processes in
red blood cells - Mechanism of propranolol induced Ca-
dependent K efflux from human RBCs
R01HL-I0018-11 Effect of aging on beating heart cells in
culture (rats)
ROlHL-10316-13 Structural studies on low density serum
lipoproteins (human)
ROlHL-10940-13 Lipid transport (rabbits, cattle, chickens)
ROlHL-10942-09 Study of genetic hypertension in rats
** POlHL-11310-12 0063 Mechanisms of cardiovascular
disease - Myocardial function, metabolism and cellular
integrity after heart surgery (dogs)
Membrane transport processes in red
I3S
* POIHI 11310 12 010? Mechanisms at cardiovatculir
disease Cardiac membrane and ion mobility (dogi)
POIHI 11351 12 0002 Cellulai and moleculii
mechanisms ol myocardial function Ellects ol hypoii*
and ischemia on ionic eichange (rats, rabbits)
POIHL 11351 12 0009 Cellulai and molecular
mechanisms of myocardial function Myocardial membiane
surface coat (rats, rabbits)
* POIHL 12157 11 Functions and mechanisms ol cell
membrane ion transport
ROIHL 12528 10 NMR relaxation ol liquid crystal systems
ROIHL 12974 10 Tracer kinetics. Hows and masses in
body oigans (human, dogs)
POIHL 1310809 0013 Clinical heart transplantation
Cardiomyopathic lymphocyte responsiveness to cultured
endothelium
ROIHL 1333908 Pharmacology of developing cardiac
tissues (chick embryo)
ROIHL 13349 06 Analysis of activation process in heart
muscle (guinea pigs, rabbits, human)
ROIHL 13921 07 The lung as a metabolic organ (animals)
P50HL 1414708 0012 Specialized center of research in
thrombosis Tissue culture study of arterial cells (human,
hamster)
P50HL 1421207 0007 Correlated studies of pulmonary
fibrosis Protein metabolism in alveolar macrophages
(rabbits, guinea pigs, human)
P50HL 14217-08 0058 Specialized center of research in
thrombosis Mechanisms of induction and inhibition ol
platelet reaction (human, pig)
P50HL 14230 07 0092 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Tissue lipids-Cell culture studies
(human)
** P50HL 1423605 0008 Prevention of premature
arteriosclerosis - Lipoproteins ol cell membranes (human)
POlHL-14388-07 0191 Regulation ol the circulation in
pathological states Regulation ol chloride transport in
epithelial membranes (turtles)
** POIHL 14414-07 0016 Environmental influences on
cardiorespiratory and cellular functions Eltects ol
pressure on membrane and cellular lunction (human,
rabbits)
ROlHL-14820-07 Factors affecting physiology ol biological
membranes (human)
ROlHL-14990-07 Lipid transport in avian species
(chickens)
P50HL-15061-07 0009 Response of lung to injury -
Alveolar macrophages (human, rabbits)
** P60HL-151 57-07 0018 Comprehensive center for sickle
cell disease - Red blood cell membrane physiology in sickle
cell anemia (human)
ROlHL-15226-06 Interaction of blood cells with fibrinogen
and fibrin (human, animals)
ROlHL-15567-05 Cardiovascular phosphoinositide
metabolism (rats)
ROlHL-15648-06 Lipid metabolism-Transport by lateral
diffusion (human, rabbit, cattle)
POIHL- 158 3 5-06 0004 Study ol muscles related to heart
disease - Actomyosin systems and cell motility (slime
molds, human)
POlHL-15835-06 0021 Study ol muscles related to heart
disease - Fast kinetic studies in muscle subcellular
organelles (animals)
ROlHL-16029-05 Bio-organic chemistry ol ozone, nitrogen
dioxide and tobacco smoke
ROlHL-16037-06 Molecular properties of cardiac
adrenergic receptors
M POlHL-161 17-05 Ion movements and membranes in
cardiovascular control
** POlHL-161 17-05 0005 Ion movements and membranes in
cardiovascular control - Properties of isolated cell
membranes (rabbits, cats)
** ROlHL-16567-04 Differentiation of the heart-cell
membrane (mice, chick)
ROlHL-16628-05 Regulation of lipid metabolism (rats)
ROlHL-16706-04 Excitation-contraction coupling and heart
failure (dogs, rabbits)
POlHL-16769-05 0002 Pathobiologic and host delense
reactions in the lung - Pathogenesis ol complement
dependent injury to the lungs (rabbits)
M POlHL-16833-04 Hemoglobin and red cell system in
hemoglobinopathies
** POlHL-16833-04 0009 Hemoglobin and red cell system in
hemoglobinopathies - Rheological studies ol sickled cells
(human)
POlHL-16833-04 0016 Hemoglobin and red cell system in
hemoglobinopathies - Calcium-indiced membrane damage
in Hb SS disease (human, animals)
M P01HL16851-04 Human red cell membrane in health and
disease
** POlHL-16851-04 0009 Human red cell membrane in
health and disease - Blood cell properties in circulatory
regulation (dogs, rabbits)
** POlHL-16851-04 0011 Human red cell membrane in
health and disease - Ultrastructurc laboratory-Core lacility
** P01HL-I685104 0012 Human red ceil membrane in
health and disease - Computer unit -Core facility
ROlHL-17080-05 Localization of pore systems in capillary
walls (rats, mice, rabbits)
P60HL-17269-04 0003 National heart and blood vessel
research and demonstration center - Atherosclerosis -Fatty
acid metabolism in cardiovascular tissue (human, chicken)
P60HI 17769 04 001/ National haati and blood vtiul
rosaarch and damonitration canlar Call mambrana (dogi.
rabbiti)
P60HI 1/769 04 0045 National heart and blood vatui
research and demonstration center Regulation ol
lipogenetis in hyperhpopiotainamia (human, liitua culture)
ROIHI l/4U4 0b Immunologic mechanitmi in heart
disease (mice)
ROIHL 17575 03 Molecular basis ol collagen platelet
interaction (human, rat)
ROIHL 1756/03 Lipoprotein cytolytic toxin interaction
(Staphylococcus aureu'.. mammals, human)
P50HL 1/648 04 007/ Study ol ischemic heart disease
Phospholipid metabolism following cardiac injury and
repair (rat)
P50HL 1/6/0 04 0023 Study ol ischemic heart disease
Energy metabolism in acute myocardial ischemic injury
(dogs)
POIHL 1/812 04 0005 Thrombosis and plasma proteins
In vitro systems ol normal platelets, white cells, sera
(human)
ROIHL 1/882 04 Regulation ol HMO COA reductase and
sterol synthesis (human, mammals)
ROlHLl/89803
(human, swine)
Cell membranes and plasma lipoproteins
Limiting lactors in oxygen uptake in the
Enzymatic regulation ol platelet lunction
ROIHL 1796704
lung
ROIHL 1850203
(human)
ROIHL 18551-03 Spectrin, actin, lipid and red cell
membrane structure
ROlHL-18553-03 Membrane defects in familial
hypercholesteremia (human)
POIHL 1857703 Lipoproteins-Cell surface interactions
POIHL 18577-03 0001 Lipoproteins -Cell surface
interactions Structural studies of serum lipoproteins in
man and dogs
POlHL-18577 03 0004 lipoproteins-Cell surface
interactions Analysis and chemical modification of
proteins in lipid transport (human, dogs)
ROIHL 18692 03 Glycosaminoglycans and lipoproteins ol
human plasma
ROlHL-18824-03 Mechanisms ol heart lailure in
myopathic hamster
P50HL-1882803 0001 Specialized center ol research in
thrombosis - Membrane biology and hemostasis (human)
P50HL-18828-03 0004 Specialized center ol research in
thrombosis - Membrane changes in platelet physiology -Role
ol complement (mice, human)
ROlHL-18887-03 Hypolipidemic drugs-Ellects on FFA-
albumin association (human, cattle)
ROlHL-19000-03 Irreversible myocardial injury (rats)
R01HL19234-03 Streptococci and heart-Cellmediated
cross-reaction (mice)
POlHL-19242-02 0002 Study ol vascular smooth muscle -
Vascular smooth muscle response to serum lipoproteins
(rats)
ROlHL-19394-03 Biochemistry and regulation ol taurine in
the heart (rats, guinea pigs, cats)
R01HL-19429-03 Phagocytosis-lngestion in alveiolar
macrophages (rabbits)
ROIHL- 194 54-02 Rheological factors in transport across
arterial wall (dogs)
' ROlHL-19673-03 Surgical aspects of shock and hypoxia
(dogs, monkeys, rats)
ROlHL-19720-03 Evaluation of anti-fibrotic agents in
pulmonary fibrosis (rats)
ROlHL-20002-03 Pulmonary complications of viral
infections (children)
ROlHL-20063-03 Pathogenesis of pulmonary mycoplasma
infections (guinea pigs, mice)
* ROlHL-2036503 Molecular mechanisms of anion transport
ROlHL-20394-03 Complement activation by heart
subcellular membranes (human, dog)
ROlHL-20594-02 Renal enzymes that regulate blood
pressure (human, rats)
ROlHL-20711-01 Structure-function relationships in red
cell NA-K pumps (goats)
ROlHL-20818-02 Platelet storage at 22 degrees C
(human)
* ROlHL-20859-02 Beta adrenergic catecholamine receptor
* ROlHL-20971-10 Membrane glycoproteins of platelets and
leukocytes (human)
R01HL-21014-01 Mechanism of the inotropic action of
cardiac glycosides
ROlHL-21030-01 Calcium regulation and hyperteniion
(rats)
* ROlHL-21 12002 Membrane dynamics in alveolar
macrophages (rabbits)
* ROlHL-21246-02 Roles of cholesterol and its metjbolic
regulation (CHO cell mutants)
ROlHL-21329-02 Beta-receptor regulation and cardiac
sites of drug action (cat, guinea pig, rat)
ROlHL-21342-02 Isolation and analysis of souium channel
from heart (frogs)
ROlHL-21394-02 Pulmonary angiotensin-converting enzyme
(rabbits)
ROIHL-21670-01 Antiarrhythmic studies on 2-substituted
aminoindenes (dogs)
ROlHL-21735-01 Electrophysiology alter healed myocardial
inlarction (cats)
(contd)
*Eidu<les routine methodokigy OR covers only general projects which preclude indexing at the specific level.
"Oiiented significanthf to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix lor investigator's name and grant number
•^'..■•ff.'
'f^'
CEL
The mechanism of collagen formation
Smooth muscle development in vitro
Regulation of active sodium transport
NDV infection-Analysis at the subcellular
Ions, water, and hypertension (human,
ROlHL-22081-20
(human, cattle)
ROlHL-22456-01 Lipoproteins in biorcgulation of the
immune response (mice, human)
ROlHL-22570-01 Interactions of sterols in biological
systems (human)
** POlHL-22619-01 0001 Cellular mechanisms of heart
failure - Cell membrane isolation and reconstitution (dogs,
lambs)
** POlHL-22619-01 0002 Cellular mechanisms of heart
failure - Structure of sodium, potassium-adenosine
triphosphatase (lambs, dogs)
" POlHL-22619-01 0004 Cellular mechanisms of heart
failure - Mechanism of action of Na, K-ATPase (sheep,
cattle)
POlHL-22633-01 0003 Cellular and molecular biology of
lipoprotein metabolism - Sterol metabolism in platelets and
megakaryocytes (human, rabbits, guinea pigs)
ROlHL-22682-01 Structure and function of high density
lipoprotein (human, rat)
ROlHL-22767-01 Model system for cardiac action
potentials (squid, axons)
^ ROlHL-22883-01 Lung epithelial cell interactions in vitro
R01ML'23010'0I Control and mechanism of platelet
aggregation (human)
ROlHL-23013-01
(chick embryo)
ROlHL-23115-01
(frogs, rats)
ROlHL-23210-01 Biology of normal and hypertrophied
pulmonary vessels (cat, human)
ROlHL-23588-01
level (chickens)
ROlHL-23600-01
dogs, rats)
" ROlHL-2390001 Mechanical measurement of cell
membrane viscosity (human)
CEU COMPONENTS, CELL NUCLEUS
ROlHL-05360-19 Cholesterol biosynthesis and its control
in liver (rats)
POlHL-09011-15 0019 A research and resource program
in blood - The transport mechanism of mRNA (rat, yeast,
ascites cells)
POlHL-19737-02 0003 Cellular and molecular aspects of
respiratory physiology ■ Cortisol-dependent alterations in
lung type II cells (rats)
ROlHL-2404801 Regulation of hemoglobin synthesis in
chick embryos
CELL COMPONENTS, CELL WALL
R01HL01803-23 0001 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Post'Streptococcal glomerulonephritis
(rabbit)
ROlHL-039 19-20 The cell suface of streptococci (rats,
human)
POlHL-12157-11 0060 Functions and mechanisms of cell
membrane ion transport - Ion transport and electrical
properties of giant-celled aiga
R01HL-I9234-03 Streptococci and heart-Cellmediated
cross-reaction (mice)
CELL COMPONENTS, CILIA
SEE ALSO DIAGNOSTIC TESTS, CYTODIAGNOSIS,
CILIOINHIBITORY TEST*
POlHL-10436-13 0016 A multidisciplinary study of
congenital heart disease - Genetic studies of congenital
heart disease (human)
R01HL-12e50-08 Environmental pathoblology of the lung
(hamsters, rats)
P50HL-19171-02 0009 Pulmonary SCOR-Lung injury by
childhood infections - Host-parasite interaction-Scanning
electron microscopy, freeze-fracture methods
P50HL-19171-02 0010 Pulmonary SCOR-Lung injury by
childhood infections - Metabolic pathways of normal and
injured respiratory cells
•* ROlHL-22560-02 Structure and motion of cilia
(Tetrahymena, mussels)
CELL COMPONENTS, CILIARY MOVEMENT
P01HL-0628S-18 0189 Cardiovascular-respiratory
physiology and biochemistry - Mucociliary clearance (cats,
dogs)
** POlHL-07896-15 0043 Environmental biomedical research
program Effect of hyperbaric oxygen on the lung (human,
rabbits)
P50HL-14153-07 0016 Johns Hopkins Lung Center-
Chronic diseases of airways - Airways defense mechanisms
(dogs)
ROlHL-14271-07 Physico-chemical properties of tracheal
mucus (dogs, frogs)
" ROlHL-16730-03 Physiology of mucociliary transport (rats,
frogs, rabbits)
** ROlHL-18308-03 Comprehensive studies of mucociliary
transport (dogs)
P50HL-19157 02 0003 Studies in cystic fibrosis and
bronchiolitis - Nasal mucosal function in patients with
cystic fibrosis
Regional mucociliary transport in the
ROlHL-19431-03
human lung
ROlHL-20 192-02
laser scattering
ROlHL-21314-02
Ciliary activity of the lung studied by
Respiratory tract secretion of ions, water
and mucus (human, dogs)
136
" ROlHL-22560-02 Structure and motion of cilia
(Tetrahymena, mussels)
CELL COMPONENTS, CYTOPLASM
ROlHL-04442-20 Mitochondrial assembly and replication
(fungi, wheat)
POlHL-090 11-15 0019 A research and resource program
in blood - The transport mechanism of mRNA (rat, yeast,
ascites cells)
ROlHL-19132-04 Role of zinc transferrin in lymphocyte
transformation (human)
ROlHL-19933-02 Membrane and red cell dysfunction In
hemolytic anemia (human)
R01HL-2298M7 Membrane-associated functions in
microorganisms (bacteria, protozoa)
ROlHL-24048-01 Regulation of hemoglobin synthesis In
chick embryos
CELL COMPONENTS, CYTOPLASMIC GRANULES
SEE ALSO CELL COMPONENTS, MICROSOMES
POlHL-06314-17 0052 Immunologic mechanisms in
cardiovascular disease - Role of cyclic nucleotides In
neutrophil function (human)
P50HL14217-08 0057 Specialized center of research in
thrombosis - Pharmacology-Platelet biochemistry (human,
animal)
P50HL- 142 17-08 0059 Specialized center of research in
thrombosis - Energy metabolism and platelet function
(human)
P50HL-18828-03 0008 Specialized center of research in
thrombosis - Biochemistry, physiology-Platelets and
subcellular platelet particles (human)
** ROlHL-19379-03 Characterization of small-granule cells in
the lung (mammals)
CELL COMPONENTS, ENDOPLASMIC RETICULUM
SEE ALSO MEMBRANE SURFACE (BIOLOGICAL) ACTIVITY
(GENERAL)
SEE ALSO MUSCLE CELLS, SARCOPLASMIC RETICULUM
SEE ALSO PROTEINS, MEMBRANE PROTEINS
POlHL-06370-17 0006 Cardiopulmonary and renal
pathology research center ■ Chemical basis of
ultrastructural changes in disease (rats)
POlHL-06835-17 0062 Cardiovascular disease - Role of
collagen in atherosclerosis (dogs, pigeons)
POlHL-09011-15 0015 A research and resource program
in blood - Regulation of synthesis and transport of diverse
proteins in liver (rats)
R01HL-12e50-08 Environmental pathoblology of the lung
(hamsters, rats)
ROlHL-15427-06 Secretion of plasma lipoproteins (rats)
P50HL- 17646-04 0012 Study of ischemic heart disease -
Role of microcirculation In progression of myocardial
ischemic injury (rat)
POlHL-19242-02 0002 Study of vascular smooth muscle -
Vascular smooth muscle response to serum lipoproteins
(rats)
ROlHL-20366-03 Protein turnover and amino acid
transport by lung (rats)
ROlHL-20594-02 Renal enzymes that regulate blood
pressure (human, rats)
ROlHL-21756-11 Vascular disease-Cytochemistry and
ultrastructure (human, rats, mice, hamsters)
CELL COMPONENTS, FLAGELLA
R01HL-16660-06 Phospholipid-cholesterol and
phospholipid-protein interactions
CELL COMPONENTS, GOLGI APPARATUS
SEE ALSO MEMBRANE SURFACE (BIOLOGICAL) ACTIVITY
(GENERAL)
SEE ALSO PROTEINS, MEMBRANE PROTEINS
P50HL-1423707 0004 Support for arteriosclerosis center
- Synthesis, secretion of normal, abnormal plasma
lipoproteins (rodents, monkeys)
POlHL-15835-06 0019 Study of muscles related to heart
disease - Vascular smooth muscle-Electron microscopy,
excitation contraction (animal)
P50HL 21006-02 0003 Specialized center of research In
arteriosclerosis - Transport of vitamin A in plasma (human,
rat)
ROlHL-21756-11 Vascular disease-Cytochemistry and
ultrastructure (human, rats, mice, hamsters)
** ROlHL-2394506 Pathologic effects on cells of modified
lipoproteins (rats, human)
CELL COMPONENTS, INTRACELLULAR
MEMBRANES
SEE ALSO MEMBRANE SURFACE (BIOLOGICAL) ACTIVITY
(GENERAL)
SEE ALSO PROTEINS, MEMBRANE PROTEINS
ROlHL-02986-21 Zonal renal change with potassium
deficiency (rats, human)
** POlHL-06285-18 0213 Cardiovascular-respiratory
physiology and biochemistry - Membrane structure and
function-Gas vacuole membrane (Halobacterium)
** ROlHL-18900-03 Intercellular factors in function of
cardiac cells
ROlHL-19072-03 Modification of tissue injury in
myocardial infarction (dogs, human)
ROlHL-19633-02 Pathogenesis and pharmacology of lung
fibrosis (rats, rabbits)
** ROlHL-21845-01 Human red cell membrane-Structure and
function
'Excludes routine methodokisy OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above sut)ject.
CEL
ROlHL-23128-01 Cardiac contractility -Ischemia and
hypoxia (rabbits, rats)
CELL COMPONENTS, LIPOSOMES
P50HL-14147-08 0015 Specialized center of research in
thrombosis - Charge related properties of phospholipid
surfaces in monolayers and vesicles
P50HL-14237-07 0004 Support for arteriosclerosis center
- Synthesis, secretion of normal, abnormal plasma
lipoproteins (rodents, monkeys)
ROlHL-14781-08 Lipid deposition in mammalian cells
(mice)
ROlHL-16318-21 Biochemistry and pharmacology of Na-K
transport
** P01HL18577-03 0003 Lipoproteins -Cell surface
interactions - Mechanism of lipid exchange in lipoproteins
and cell membranes
ROlHL-18818-04 Stereochemical mechanism of sickling of
hemoglobin S (human)
POlHL-18827-02 0005 Platelet vessel wall interactions in
thrombogenesis - Platelet vessel wall interactions in
thrombogenesis (human)
** ROlHL-19721-03 Lung inflammation-Lysosomal proteases
and liposomes (human, rabbits)
ROlHL-20254-02 Probes of heart and nerve membranes-
Fluorescent dyes
ROlHL-20303-03 Cholesterol distribution in erythrocyte
membrane (human, animals)
ROlHL-2036503 Molecular mechanisms of anion transport
ROlHL-21845-01 Human red cell membrane -Structure and
function
** ROlHL-22470-01 Liposome myocardial uptake in infarct
and ischemia (dogs, rats, mice)
POlHL-22602-01 0001 Pathophysiology of the
endothelium - Platelet-endothelial interactions in vitro
(human, cattle)
POlHL-22619-01 0001 Cellular mechanisms of heart
failure - Cell membrane isolation and reconstitution (dogs,
lambs)
POlHL-22619-01 0003 Cellular mechanisms of heart
failure - Digitalis induced inotropy in myocardial ischemia
heart failure (animals)
POlHL-22619-01 0009 Cellular mechanisms of heart
failure - Sarcoplasmic reticulum in cardiac, skeletal and
smooth muscle (rabbits, dogs)
POlHL-22633-01 0004 Cellular and molecular biology of
lipoprotein metabolism - Lipid-lipid and lipid-protein
interactions in serum lipoproteins (human, rats)
ROlHL-228 13-01 Palmitylcarnitine inhibition of ion pumps
in ischemia (dogs)
** R23HL-22839-01 Cellular translation of liposomally-
delivered mRNA (human, mammals)
CELL COMPONENTS, LYSOSOMES
ROlHL-02986-21 Zonal renal change with potassium
deficiency (rats, human)
POlHL-08682-15 0020 Regulation of the cardiovascular
system - Hepatic metabolic basis of shock (rat)
ROlHL-10503-13 Cardiac ion transport and ultrastructure
(rats, guinea pigs, rabbits)
ROlHL-12766-09 Structure-function relation of blood
vessels (rats, monkeys)
ROIHL- 12869-09 Arterial metabolism, diabetes and
atherogenesis (rats, rabbits)
ROlHL-13636-08 Effects of pharmacologic agents on heart
metabolism (human, rodents)
P50HL-14212-07 0006 Correlated studies of pulmonary
fibrosis - Alveolar macrophage physiology (human, rodents,
rabbits)
P50HL-14217-08 0057 Specialized center of research in
thrombosis - Pharmacology-Platelet biochemistry (human,
animal)
ROlHL-14700-05 Humoral and lung protease-antlprotease
role in obstructive disease (human)
ROlHL-14706-07 Fetal hearts in organ culture (mice)
POlHL-16769-05 0002 Pathobiologic and host defense
reactions in the lung - Pathogenesis of complement
dependent injury to the lungs (rabbits)
POlHL-16769-05 0004 Pathobiologic and host defense
reactions in the lung - Pathogenesis of Pseudomonas and
Serratia pneumonias (rabbits)
P50HL-17648-04 0025 Study of ischemic heart disease -
Destruction and repair of cardiac muscle cell constituents
(rat)
" P50HL-17669-04 0011 Ischemic heart disease center
(SCOR) - Lysosomal function and lysosomal enzymes in
normal and ischemic heart (rabbit)
** ROlHL-18157-04 Subcellular events in atherosclerosis
(human, rabbits, calves)
** ROlHL-18258-04 Regulation of protein degradation in
heart (rats)
P50HL-18318-03 0014 Pathogenesis and complications of
hypertension - Arterial metabolism and atherogenesis (rat,
rabbit)
ROlHL-18631-03 Ultrastructural correlates of myocardial
ischemia (rats, swine)
ROlHL-18647-03 Ischemic myocardial injury in cultured
heart cells (rats)
ROlHL-18723-03 Genetic heterogeneity of acid lipase-
Atherosclerosis (human)
** ROlHL-19072-03 Modification of tissue injury in
myocardial infarction (dogs, human)
(contd)
1
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
Cfl
** HOIHL 19148 OJ Myotaidial oiltnglle lipid itiuctuie and
lunclion (doge lal)
PMWl 1918/ 02 0004 Padiainc pulmonatv SCOR Hyaline
mtmbiane diseasa Hyaline inembiane disease Surface
active matatial. lamallai bodies (mice, rats)
*' ROIHl 19/?I 03 Luni inllammation Lysosomal proteases
and liposomes (human, rabbits)
ROIHL l9/2b03 Complement induced pulmonary injury
(dogs, rabbits, sheep)
ROIHL 20104 03 Pulmonary granulomaloii!^ intlammalions
(mice)
R0IHL2012S02 Cyclic nucleotides and alveolar
macrophage activation (rabbits)
ROIHL 20394 03 Complement dctivalion by heart
subcellular membranes (humdn. dog)
ROIHL 2069S 02 Stored plateletes (human)
PQIHL 20948 02 0001 Molecular basis ot cholesterol
metabolism Biochemical and ultiastructural
characteiualion ot LDl in human libroblasts
R23HL'2ni6 02 Mechanisms ot membrane and tissue
damage in lung (dogs, rabbits)
ROIHL 2114001 Studies of pulmonay alveolar
macrophage function (rabbits)
•* R23HL 2141102 Control ot entraceliular lysosomal
hydrolase levels (rats)
•* ROIHL 2U56 11 Vascular disease- Cytochemistry and
ultrastructure (human, rats. mice, hamsters)
POlHL-2263301 0002 Cellular and molecular biology of
lipoprotein metabolism Sterol metabolism in tissue
culture cells
ROlHL-2273901 Evolution and progression of pediatric
atherosclerosis
ROIHL 2314201 Mechanisms of membrane in|ury m
myocardial ischemia (dog)
ROIHL 2320601 Repetitive exercise and cardiac
enlargement (dogs)
CELL COMPONENTS, MICROFILAMENTS
ROlHL-09125-14 Ultrastructural cytochemistry (human,
chick)
P01HL1583206 0001 Chemical structural predispositions
to lung injury ■ Chemical composition of lung connective
tissue proteins (human, animals)
** POIHL 15832 06 0009 Chemical-structural predispositions
to lung injury - Immunology-Enzyme degradation products
of human lung elastin and microfibril
** POlHL-15832-06 0012 Chemical-structural predispositions
to lung injury - Contractile structures and contractility in
cells of lung respiratory tract
POlHL-15835-06 0004 Study of muscles related to heart
disease - Actomyosin systems and cell motility (slimc
molds, human)
P50HL-1 7646-04 0012 Study of ischemic heart disease -
Role of microcirculation in progression of myocardial
ischemic injury (rat)
ROlHL-1 797304 Cultured aortic endothelial cells (human.
cattle, dogs, swine)
POlHL-18645-03 0003 Biology of the artery wall and
atherosclerosis - Synthesis of connective tissue proteins by
smooth muscle cells (human, monkeys)
ROlHL-19779-03 Biochemical basis of oxygen damage to
lung cells (guinea pigs, rats)
ROlHL-20666-02 Cell biology of platelet preservation
Microstructural integrity of stored human
(human)
** ROlHL-20718-02
platelets
ROlHL-20902-02 Studies on marginal band system of
erythrocytes (amphibians, reptiles, fish)
ROlHL-21988-01 Biochemistry of human platelet
chemotaxis
ROlHL-23233-01 Pulmonary artery intermediate filament
structure (cattle)
CEU COMPONENTS, MICROSOMES
SEE ALSO CELL COMPONENTS, CYTOPUSMIC GRANULES
SEE ALSO CELL COMPONENTS, ENDOPLASMIC RETICULUM
SEE ALSO CELL COMPONENTS, RIBOSOMES
ROlHL-02477-23 Biosynthesis and function of lipids
(microorganisms, rats)
POlHL-03 174-23 0010 Mechanisms of acute vascular
reaction to injury - Search for mutagens in the human
blood (bacteria, animals)
ROlHL-03734-18 Metabolism of arterial tissue in
atherosclerosis (rabbits)
ROlHL-08634 15 Enzymic cholesterol synthesis (human,
rats, protozoa, yeast)
POlHL-08899-14 0062 Tolerance to respiratory gases in
health and disease Influence of oxygen at high pressure
upon oxidation (rats)
ROlHL-10940-13 Lipid transport (rabbits, cattle, chickens)
R01HL12869-09 Arterial metabolism, diabetes and
atherogenesis (rats, rabbits)
ROlHL-13302-09 Uptake and metabolism of lipids by the
liver (rats)
** ROlHL-13619-09 Microsomal electron transport in liver
and heart (human, mammals)
P50HL-14217-08 0057 Specialized center of research in
thrombosis - Pharmacology-Platelet biochemistry (human.
animal)
P01HL14388 07 0172 Regulation of the circulation in
pathological states • cAMP-dependent protein kinase <rom
heart and vascular smooth muscle (guinea pigs)
137
POIHL 14414 0/ OOlb Inviiunmentnl intluenms un
catdiorespiralury and callulnr tunilions (fleets ot
pressure on membiane and cellular function (human,
rabbits)
ROIHl 15698 12 fautois affecting the ailion of
anticoagulants (rats, human)
POIHL 1611/05 0001 Ion movements and membranes in
cardiovascular control Developmental studies of
contractile cell lunclions (rats, rabbits, olasmobranch)
POIHL 1611/05 0002 Ion movements and membranes in
cardiovascular control fluorescence and excitation
contraction coupling in heart (frogs)
POIHL 1660/05 000/ Calcium ion and control of
cardiovascular function Ultrastructure and conformation
in sarcoplasmic reticulum (rabbits)
P60HL 1/269 04 0003 National heart and blood vessel
research and demonstration center Atherosclerosis Fatty
acid metabolism in cardiovascular tissue (human, chicken)
P50HL 17648 04 002/ Study ot ischemic heart disease
Phospholipid ntetabclisni following cardiac injury and
repair (rat)
ROIHL 18181 04 Surlactant metabolism -Alveolar cells and
lung disease (mice, rabbits)
ROIHL 1818504 Cardiac glycosides and diuretics- Role of
NaO pump (dogs)
ROIHL 19012 03 Smooth muscle of resistance vessels in
hypertension (rats)
ROIHL 19027-03 Calcium and cyclic AMP in causation of
hypertension (rats)
R23HL 19605-01 Lipid requirement of the lung mono
oxygenase system (rabbits)
POIHL 19737 02 0009 Cellular and molecular aspects of
respiratory physiology Regulation of tissue oxygen tension
and body carbon monoxide stores (human, dogs)
ROlHL-19772-02 Role of warfarin metabolism in
antivitamin K activity (rats)
ROIHL 204 11-03 Platelet fatty acid metabolism In
diabetes (rat, rabbit, guinea pig)
ROIHL 20577-03 The mechanism of action of vitamin K
** ROlHL-21099-02 Subcellular changes of blood vessels in
hypertension (rats)
ROlHL-21812-02 Actions of drugs and ions on cardiac
membranes (rabbits, guinea pigs)
ROlHL-22946-01 Prostaglandins, platelet aggregation and
vasoactivity (human, rats, rabbits)
R01HL-23142-01 Mechanisms of membrane injury in
myocardial ischemia (dog)
CELL COMPONENTS, MICROTUBULES (GENERAL)
POlHL-090 11-15 0015 A research and resource program
in blood - Regulation of synthesis and transport of diverse
proteins in liver (rats)
ROlHL-09125-14
chick)
Cll
cm COMPONINTS, MITOCMONDRIA
HO I HI 00082 JO
Irogi. rats)
Ultrastructural cytochemistry (human,
Biochemistry and physiology of human
ROlHL-13336-09
platelets
R01HL13870-09 Control of myocardial sarcotubular
calcium stores (dogs)
ROlHL-13909-27 Physiochemistry and immunology of
macromolecules
ROlHL-1530807 Assays for peptides of lipoproteins
(human)
P01HL1583506 0004 Study of muscles related to heart
disease • Actomyosin systems and cell motility (slime
molds, human)
P60HL-17269-04 0019 National heart and blood vessel
research and demonstration center • Sarcoplasmic
reticulum (dog, rabbit, hamster, cat)
P60HL-1 7269-04 0021 National heart and blood vessel
research and demonstration center - Growth and
development of heart -Ultrastructure (dog, guinea pig, rat,
cat)
P50HL-17646-04 0012 Study of ischemic heart disease -
Role of microcirculation in progression of myocardial
ischemic injury (rat)
R01HL1893503 Platelets, fibrinogen, soluble fibrin
interaction (human)
' ROlHL-19323-03 Studies of platelet microtubule protein
ROlHL-19721-03 Lung inflammation-Lysosomal proteases
and liposomes (human, rabbits)
ROlHL-19779-03 Biochemical basis of oxygen damage to
lung cells (guinea pigs, rats)
Cellular mechanisms of renin secretion
Analysis of heart cell contraction (rats)
Stored plateletes (human)
Microstructural integrity of stored human
ROlHL-20278-02
(rats)
ROlHL-20643-02
ROlHL-20695-02
ROlHL-207 18-02
platelets
ROlHL-2090202 Studies on marginal band system of
erythrocytes (amphibians, reptiles, fish)
P50HL-2 1006-02 0003 Specialized center of research in
arteriosclerosis - Transport of vitamin A in plasma (human,
rat)
ROlHL-21970-01 Myofibrillar assembly and breakdown in
cardiac muscle (rats)
ROlHL-22444-01 Bronchial mucus production in organ
culture (human)
ROlHL-22560-02 Structure and motion of cilia
(Tetrahymena, mussels)
ROlHL-23161 01 0004 Biology of myocardial ischemia •
Structure of myofibrils and membranes in early ischemia
(dogs, rabbit, rodents)
Irantmsmbrann movamanit (barnaclca,
Rggulalion ol inirtabolitm by drugt and
ROIHI 0IHI3 25
hormones (rats)
ROIHL 02063 23 Biothemnlry and (unction ot lipid* and
cell membranes (human, yeast, animals)
ROIHL 04442 20 Mitochondrial assembly and replication
(fungi, wheat)
POIMI 06308 18 0025 Methanisms and therapy of
circulatory disease Subcellular calcium pools in the
genesis of airhylhmias (dogs)
P01HL06312 1/ 0033 Surgical cardiology Studies in
cryopreservations (rats)
POIHL 06835 17 0062 Cardiovascular disease Role of
collagen in atherosclerosis (dogs, pigeons)
POIHL 08682 15 0020 Regulation of the cardiovascular
system Hepatic metabolic basis of shock (rat)
ROIHL 09172 15 Protein and RNA synthe-.i'. in heart
muscle (rats)
ROlHL-09364 14 Ion transport by heart mitochondria
(cattle, rat, rabbit)
R01H109489 13 Myocardial lipid metabolism and
regulation (rats)
POIHL 123/3 10 0005 Cardiopulmonary physiology and
pathophysiology Characterization of fetal and neonatal
myocardium (human, cats)
ROIHL 1299/ 0/ Myocardial defects induced by potassium
depletion (human, rats, cats)
ROIHL 13028 09 Regulation of myocardial fatty acid
metabolism (rats)
ROIHL 1330209 Uptake and metabolism ol lipids by the
liver (rats)
POIHL 13737 07 0031 Assisted circulation ■ Myocardial
ischemia -Biochemical changes (dogs)
P50HL-14217-08 0057 Specialized center of research in
thrombosis Pharmacology -Platelet biochemistry (human,
animal)
Regulation of the circulation in
Subcellular distribution of calcium
Regulation of the circulation in
Functional studies of selected proteins
POIHL 1438807 0153
pathological states
(rats)
POIHL 14388-07 0175
pathological states
from cardiac muscle
ROlHL-14483-08 Energy conservation in heart
mitochondria (cattle. E coli. human)
ROlHL-14717-06 Hemodynamics and heart structure -
Ventricular overload (dogs)
ROlHL-14730-07 Fatty acid beta-oxidation in normal and
ischemic hearts (rabbits)
P50HL-15061-07 0002 Response of lung to injury -
Oxidative metabolism, phospholipid synthesis, and response
to toxins (rats)
ROlHL-15698-12 Factors affecting the action of
anticoagulants (rats, human)
ROlHL-15740-06 In vitro studies on heart cell function
(rats)
POlHL-15835-06 0013 Study of muscles related to heart
disease - Cardiac bioenergetics (rats)
POlHL-15835-06 0019 Study of muscles related to heart
disease • Vascular smooth muscle-Electron microscopy,
excitation contraction (animal)
POlHL-15835-06 0021 Study of muscles related to heart
disease ■ Fast kinetic studies in muscle subcellular
organelles (animals)
ROlHL-15888-05 Comparative stereology of the
myocardium (birds, mammals)
POlHL-16251-06 0004 Membrane-bound enzymes in heart
and other tissues - Biosynthesis and degradation of
succinate dehydrogenase, histidyl (yeast, mammal)
ROlHL-1670604 Excitation-contraction coupling and heart
failure (dogs, rabbits)
P60HL-17269-04 0003 National heart and blood vessel
research and demonstration center - Atherosclerosis -Fatty
acid metabolism in cardiovascular tissue (human, chicken)
P60HL-17269-04 0018 National heart and blood vessel
research and demonstration center - Mitochondria and
energetics (rabbits, dogs)
P60HL-1726904 0021 National heart and blood vessel
research and demonstration center - Growth and
development of heart -Ultrastructure (dog, guinea pig, rat,
cat)
P50HL-1764604 0007 Study of ischemic heart disease -
Prediction of myocardial ischemic injury by analysis of
plasma CPK isoenzymes
P50HL-17648-04 0025 Study of ischemic heart disease
Destruction and repair of cardiac muscle cell constituents
(rat)
P50HL-17648-04 0027 Study of ischemic heart disease -
Phospholipid metabolism following cardiac injury and
repair (rat)
P50HL- 17648-04 0031 Study of ischemic heart disease -
Ultrastructural consequences of myocardial ischemia (rat)
P50HL-17667-04 0012 Study of ischemic heart disease -
Biochemistry of normal and ischemic heart Glycolysis (rats)
P50HL17669 04 0006 Ischemic heart disease center
(SCOR) - Studies of hypoxic, acidotic and ischemic cardiac
muscle (dogs)
P50HL-17670-04 0023 Study of ischemic heart disease -
Energy metabolism in acute myocardial ischemic injury
(dogs)
(contd)
'Exclude: nxitlne methodok>gy OR covers only general projects which preclude
**Onented signihcanthi to above subject-
indexing at the specific level.
M Grant has subprojects descnbing specific research aspects.
See Appendix (or investigator's name and grant number.
{-'/-::•>>-
CEL
138
CEL
P50HL-1 7682-04 0010 Study of ischemic heart disease ■
Core clinical enzyme laboratoty (human, mice, dogs, rats)
P50HL-17682-04 0018 Study of ischemic heart disease ■
Biochemistry of ischemia -Heart cell and organ culture
(mice, rats, cattle)
ROlHL-17736-04 Metabolic change during cardiac
ischemia (rats, dogs)
POlHL-17813-04 0007 Lung disease and the oxygenation
of blood and tissue - Studies on the function of myoglobin
(dogs)
ROlHL-18038-03 Structure and function of heart
mitochondria (cattle)
ROlHL-18070-04 Regulation of intrapulmonaty airways
and vessels (human, animals)
ROlHL-18089-04 Fatty acid metabolism in heart and its
regulation (swine, rats)
R01HL18288-04 Intraoperative protection of the
myocardium (dogs, rats)
ROlHL-18527-03 Subcellular response of heart to
functional overload (hamsters, rats)
POlHL-1870803 0003 Oxygen, energy and contractility in
cardiac tissue - Structural-functional studies on cytochrome
c oxidase
POlHL-18708-03 0005 Oxygen, energy and contractility in
cardiac tissue - Cytosolic calcium homeostasis and
bioenergetics of cardiac tissue (animals)
POlHL-18708-03 0009 Oxygen, energy and contractility in
cardiac tissue - Regulation of oxygen utilization of cardiac
tissue (rats, rabbits)
POlHL-18708-03 0010 Oxygen, energy and contractility in
cardiac tissue - Tissue oxygen utilization (rats, dogs)
RClHL-19012-03 Smooth muscle of resistance vessels in
hypertension (rats)
ROlHL-19044-03 Effect of drugs on development of
cardiac failure (cats)
ROlHL-19299-03 Myoglobin and oxygen supply to heart
and muscle cells (rats, pigeons)
ROlHL-19378-03 Relation of mitochondrial changes to
cardiac failure (dogs, rats)
POlHL-19737-02 0006 Cellular and molecular aspects of
respiratory physiology - Tissue oxygenation and
mitochondrial respiratory activity (sheep)
POlHL-19737-02 0013 Cellular and molecular aspects of
respiratory physiology - Cell metabolism analytical facility
ROlHL-20177-02 Effects of erythrocyte deformability on
tissue perfusion (rats)
ROlHL-20308-02 Regulation of myocardial acylcamitine
transport (rats)
ROlHL-20394-03 Complement activation by heart
subcellular membranes (human, dog)
ROlHL-20408-03 Hyperlipidemia in diabetics during
muscular training (human)
ROlHL-20426-03 Myocardial function in diabetes mellrtus
(dog, rat)
ROlHL-20544 02 Integrated regulation of myocardial
energy metabolism (rats, guinea pigs)
P01HL-20592-02 0010 Cell biology of cardiac and
skeletal muscle - Mitochondrial genesis during myocardial
cell hypertrophy and hyperplasia (rats)
POlHL-20592-02 0011 Cell biology of cardiac and
skeletal muscle - Myosin and cytochrome oxidase
messenger RNAs (chicken)
ROlHL-20610-02 Nerve growth factor and obstructive
cardiomyopathy (dogs)
ROlHL-20909-02 Clofibrate-enhanced lipid oxidation by
peroxisomes (rats)
ROlHL-21014-01 Mechanism of the inotropic action of
cardiac glycosides
ROlHL-21371-02 Energy loss microanalysis of myocardial
cations
ROlHL-21670-01 Antiarrhythmic studies on 2-substituted
aminoindenes (dogs)
ROlHL-21756-11 Vascular disease -Cytochemislcy and
ultrastructure (human, rats, mice, hamsters)
R01HL-22008-01 Left ventrivular calcium content and
contractility (rats)
ROlHL-22039-02 Ion transport in cardiac muscle (dogs,
rodents, cattle)
ROlHL-22174-01 Assembly of membranes in heart and
yeast mitochondria
R01HL-22281-01 Microprobe analysis and metabolite
levels of ischemic mycardium (dogs)
ROlHL-22290 01 Cardiac energy metabolism and protein
synthesis (mice)
POlHL-226 19-01 0003 Cellular mechanisms of heart
failure Digitalis induced inotropy in myocardial ischemia
heart failure (animals)
P01HL22619-01 0008 Cellular mechanisms of heart
failure - Molecular mechanisms and differential contractile
responsiveness m VSM (dogs)
' POlHL-22619-01 0010 Cellular mechanisms of heart
failure Mitochondria in heart and smooth muscle (rabbits,
rats, dogs)
ROlHL-22981-17 Membrane-associated functions in
microorganisms (bacteria, protozoa)
ROlHL-23142-01 Mechanisms of membrane injury in
myocardial ischemia (dog)
ROlHL-23153-01 Mechanisms of altered CA20 transport in
ischemic heart (dog, rabbit)
ROlHL-23161-01 0001 Biology of myocardial ischemia -
Mitochondrial lipid metabolism and cardiac ischemia (rat,
dog)
ROlHL-23161-01 0005 Biology of myocardial ischemia -
Localization of complement in myocardial infarction (dog)
** ROlHL-23166-01 Pathology of mitochondria in ischemic
myocardium (rats, cattle)
ROlHL-23206-01 Repetitive exercise and cardiac
enlargement (dogs)
CELL COMPONENTS, MITOCHONDRIAL
MEMBRANE
SEE ALSO MEMBRANE SURFACE (BIOLOGICAL) ACTIVITY
(GENERAL)
SEE ALSO PROTEINS, MEMBRANE PROTEINS
ROlHL-10503-13 Cardiac ion transport and ultrastructure
(rats, guinea pigs, rabbits)
** ROlHL-12576-10 Bioenergetics apparatus in heart
mitochondria
ROlHL-14461-08 Cardiac metabolism in heart failure
(rats)
P60HL-17269-04 0018 National heart and blood vessel
research and demonstration center - Mitochondria and
energetics (rabbits, dogs)
P50HL-17648-04 0031 Study of ischemic heart disease -
Ultrastructural consequences of myocardial ischemia (rat)
ROIHL- 180 38-03 Structure and function of heart
mitochondria (cattle)
R01HL18647-03 Ischemic myocardial injury in cultured
heart cells (rats)
ROlHL-18746-02 Chemical studies on proteolipid
apoproteins (cattle)
P01HL-I9242-02 0002 Study of vascular smooth muscle -
Vascular smooth muscle response to serum lipoproteins
(rats)
Spectroscopic studies of respiratory
ROlHL-19392-03
metalloproteins
ROlHL-220 50-01
ROlHL-23153-01
Organization of succinic oxidase in heart
Mechanisms of altered CA20 transport in
ischemic heart (dog, rabbit)
ROlHL-23161-01 0001 Biology of myocardial ischemia -
Mitochondrial lipid metabolism and cardiac ischemia (rat,
dog)
CELL COMPONENTS, NUCLEAR MEMBRANE
SEE ALSO MEMBRANE SURFACE (BIOLOGICAL) ACTIVITY
(GENERAL)
SEE ALSO PROTEINS, MEMBRANE PROTEINS
POlHL-09011-15 0019 A research and resource program
in blood - The transport mechanism of mRNA (rat, yeast,
ascites cells)
CELL COMPONENTS, ORGANELLES
ROlHL-13870-09 Control of myocardial sarcotubular
calcium stores (dogs)
P50HL-142 14-07 0020 Newborn lung center for hyaline
membrane disease - Epidermal grov«th factor effect -Lung
differentiation, maturation (human, rabbit)
P50HL-142 14-07 0021 Newborn lung center for hyaline
membrane disease - Development of surfactant system-
Surfactant production and release (rat. rabbit)
P50HL-142 14-07 0022 Newborn lung center for hyaline
membrane disease - Functional integrity of surtactant
system -Hyaline membrane disease (lamb, rat)
ROlHL-15740-06 In vitro studies on heart cell function
(rats)
** POlHL-15835-06 0021 Study of muscles related to heart
disease - Fast kinetic studies in muscle subcellular
organelles (animals)
ROlHL-18032-03 Development of normal and myopathic
mammalian heart (hamsters)
ROlHL-181 57-04 Subcellular events in atherosclerosis
(human, rabbits, calves)
ROlHL-18629-04 Influence of aging and hypertension on
the myocardium (rats)
P50HL-191 85-02 0001 Pulmonary SCOR -Neonatal
respiratory distress syndromes - Sites of synthesis,
secretion and structure of surface active material (rat)
** P50HL-191 85-02 0002 Pulmonary SCOR -Neonatal
respiratory distress syndromes - Biochemistry,
ultrastructure-Pulmonary surface active material (human,
animal)
ROlHL-20394-03 Complement activation by heart
subcellular membranes (human, dog)
R01HL-20902-02 Studies on marginal band system of
erythrocytes (amphibians, reptiles, fish)
ROlHL-22685-01 Drugs and excitation-contraction coupling
in heart (animals)
CELL COMPONENTS, PEROXISOMES
POlHL-09011-15 0015 A research and resource program
in blood - Regulation of synthesis and transport of diverse
proteins in liver (rats)
P60HL-1 7269-04 0021 National heart and blood vessel
research and demonstration center - Growth and
development of heart -Ultrastructure (dog, guinea pig, rat,
cat)
** ROlHL-181 57-04 Subcellular events in atherosclerosis
(human, rabbits, calves)
ROlHL-20909-02 Clofibrate-enhanced lipid oxidation by
peroxisomes (rats)
ROlHL-21756-11 Vascular disease -Cytochemistry and
ultrastructure (human, rats, mice, hamsters)
CELL COMPONENTS, POLYSOMES
SEE ALSO CELL COMPONENTS, RIBOSOMES
'Excludes routine methodokigy OR covers only general projects which preclude indexing
"Oriented significantly to above subject.
** POlHL-09011-15 0015 A research and resource program
in blood - Regulation of synthesis and transport of diverse
proteins in liver (rats)
ROlHL-09562-14 Cardiac protein synthesis, overioad,
alcohol and anoxia (guinea pigs)
POlHL-1 1351-12 0004 Cellular and molecular
mechanisms of myocardial function - Molecular
mechanisms of contractile function and differentiation
(animals)
ROlHL-15026-12 Quantitative genetic control of protein
synthesis (human, primates, mammals)
P50HL- 15062-07 0009 Study of lipoproteins, artery wall,
and atherosclerosis - Plasma lipoprotein biosynthesis
(Rhesus monkeys)
ROlHL-16445-05 Regulation of plasma protein
biosynthesis (rats, rabbits)
P01HL-22ei9-01 0007 Cellular mechanisms of heart
failure - Regulation of contractile protein levels in heart
muscle (rats)
CEU COMPONENTS, RIBOSOMES
SEE ALSO CELL COMPONENTS, POLYSOMES
SEE ALSO NUCLEIC ACIDS, RRNA
POlHL-06314-17 0051 Immunologic mechanisms in
cardiovascular disease - Conformational studies of
phospholipid membranes and proteins
POlHL-09011-15 0019 A research and resource program
in blood - The transport mechanism of mRNA (rat, yeast.
ascites cells)
ROlHL-14717-06 Hemodynamics and heart structure -
Ventricular overload (dogs)
POlHL-16137-05 0008 Alveolar biology - Macromolecular
events in pulmonary cells in toxic environments (animals)
POIHL- 174 19-04 0006 Studies on mechanisms of
hemostasis - Effect of hormones, drugs and other agents
on fibrinogen synthesis (chick)
ROlHL-20344-02 Regulation of protein turnover in lung
tissue (rats)
ROlHL-20388-03 Regulation of protein turnover in diabetic
heart (rat)
POlHL-226 19-01 0007 Cellular mechanisms of heart
failure - Regulation of contractile protein levels in heart
muscle (rats)
ROlHL-22651-01 Control of protein metabolism in heart
muscle
CELL COMPONENTS, VACUOLES
" POlHL-06285-18 0213 Cardiovascular-respiratory
physiology and biochemistry - Membrane structure and
function-Gas vacuole membrane (Halobacterium)
POlHL-12157-11 0060 Functions and mechanisms of cell
membrane ion transport - Ion transport and electrical
properties of giant-celled aiga
CELL CONTACT INHIBITION
SEE CELL GROmn REGUUTION, CONTACT INHIBITION
CELL CONTROL MECHANISMS (CELL GROWTH-
PROLIFERATION)
SEE CELL GROVirrH REGULATION
CELL COUNTING AND SEPARATION
SEE CELL SORTING
CEU CULTURE
SEE TISSUE (CELL) CULTURE*
CELL CULTURE COLLECTIONS
SEE TISSUE (CELL) CULTURE, CELL CULTURE COLLECTIONS
BANKS AND REGISTRIES
CELL CYCLE, TURNOVER (POPULATION STUDIES)
SEE POPULATION STUDIES CELL
CELL CYCLE, TURNOVER (REGULATION OF)
SEE CELL GROWTH REGULATION
CELL DEATH
SEE ALSO CELL DESTRUCTION, CYTOLYSIS
SEE ALSO DISEASES, PATHOLOGIC PROCESSES, NECROSIS
SEE ALSO TOXICOLOGY, CYTOTOXICITY
** POlHL-06370-17 0006 Cardiopulmonary and renal
pathology research center - Chemical basis of
ultrastructural changes in disease (rats)
POlHL-06664-17 0034 Cardiopulmonary function in
remediable vascular disease - Role of hyperosmolar agents
in ischemic heart disease (dogs)
POlHL-11310-12 0063 Mechanisms of cardiovascular
disease Myocardial function, metabolism and cellular
integrity after heart surgery (dogs)
** P50HL-14214-07 0022 Newborn lung center for hyaline
membrane disease - Functional integrity of surtactant
system-Hyaline membrane disease (lamb, rat)
** P60HL-17269-04 0018 National heart and blood vessel
research and demonstration center - Mitochondria and
energetics (rabbits, dogs)
P50HL-17670-04 0023 Study of ischemic heart disease -
Energy metabolism in acute myocardial ischemic injury
(dogs)
** ROlHL-18284-04 Aging erythrocytes -Bio-recognition and
elimination (monkeys)
ROlHL-19000-03 Irreversible myocardial injury (rats)
R23HL-19584-01 Alveolar macrophage responses to toxic
particle exposure (guinea pigs, human)
(contd)
at the specific level.
M Grant has subprojeds describing specific research aspects.
See Appendix for investigator's name and grant number.
CEl
POIHI 70993 or 0008 Population dynamics ol attarial
calls in atharo|«nasis An|lo(a>lcitv ol cholasteiol
oiidalion in atharoianasis liabbits)
*• R23H1211160? Machanisms ot mambiane and tissue
damaia In lung ldo|s. labbitsl
ROIHI 72883 01 Lung apithalial call intaiactions in vitio
** ROIHL 23138 01 Myocatdiil ischamia (dogs, rats, chick
ambryo)
ROIHL 231!i3 01 Mechanisms ol altered CA20 transport in
ischemic heart (dog. rabbit)
ROIHL 23b88 01 NOV inteclion Analysis at the subcellular
level (chickens)
CEU DEDIFFERENTIATION
SEE ALSO CELL DIFFERENIIAIION
POIHL 18708 03 0008 Oxygen, energy and contractility In
cardiac tissue Cardiac cell culture lacllity
ROIHL 22729 01 Intracellular degradation ol newly
synthesind collagen (human, chick, rabbit)
CEU DESTRUCTION, AUTOPHAGY
PSOHL 17648 04 002S Study ol ischemic heart disease
Dastructicn and repair ol cardiac muscle cell constituents
(rat)
ROIHL 20695 02 Stored plateletes (human)
CEU DESTRUCTION, CYTOLYSIS
ROIHL 12760-09 Surlace studies ot membrane lipids and
proteins
R01HL1756703 Lipoprotein-cytolytic toxin interaction
(Staphylococcus aureus, mammals, human)
P50HL 1766704 0045 Study ot ischemic heart disease
Pathology of myocardial ischemic necrosis (human)
ROIHL 18824 03 Mechanisms of heart failure in
myopathic hamster
CEU DIFFERENTIATION
SEE ALSO CELL DEDIFFERENTIATION
SEE ALSO GROWTH AND DEVELOPMENT. HISTOGENESIS
R01HL01803 23 0016 Arteriosclerosis, glomerulonephritis,
rheumatic fever Synthesis of basement membrane
collagen by endothelial cells (human)
ROlHL-0594918 Biochemistry of muscle contraction (rats,
rabbits)
P01HL06285-18 0186 Cardiovascular-respiratory
physiology and biochemistry - Leukocyte hormone receptors
and cyclic nucleotides (tissue culture)
POlHL-06285-18 0209 Cardiovascular-respiratory
physiology and biochemistry Metabolic studies of Isolated
lung cells (human, animals)
** P01HL11310-12 0097 Mechanisms of cardiovascular
disease • Structural-functional relationships of neuronal
differential alloantigens (mice)
POlHL-11310-12 0098 Mechanisms of cardiovascular
disease - Protein chemistry of thy-1 and related
synaptosomal proteins (mice)
ROlHL-11551-11 RNA and protein synthesis in repair of
heart injury (mice, rats)
** POlHL-12157-11 0037 Functions and mechanisms of cell
membrane ion transport - Developing structure of heart
cells in tissue culture
ROlHL-13831-08 Factors regulating embryonic cardiac
morphogenesis (chick, salamandra)
P50HL-14214-07 0023 Neviborn lung center for hyaline
membrane disease - Regulation of fetal lung maturation-
Vitamin A (rat. rabbit, sheep, human)
ROlHL-15026-12 Quantitative genetic control of protein
synthesis (human, primates, mammals)
ROIHL- 15448-06 Surgical and metabolic aspects of
venous grafts, (dogs, monkeys, rabbits)
ROlHL-15647-06 Hematopoietic studies of cyclic
hematopoiesis (dogs)
P01HL-15835-06 0025 Study of muscles related to heart
disease - Cellular biology of vascular smooth muscle
(guinea pig)
P60HL-1 5999-05 0019 Miami comprehensive sickle cell
center - Fetal-adult hemoglobin switch (mouse, monkey)
P60HL- 16008-06 0019 Wayne State University
comprehensive sickle cell center - Cell mediated immunity
in sickle cell anemia (human)
POlHL-16137-05 0004 Alveolar biology • Subcellular
processes and controls in the surfactant system (animals)
** ROlHL-1656704 Differentiation of the heart-cell
membrane (mice, chick)
ROIHL 16654-06 Regulation in developing erythroid cells
(human)
ROlHL'16711-05 RBC and endothelial membrane material
characteristics (human)
ROlHL-16952-05 Cardiovascular pathology (rats, rabbits)
P60HL- 1726904 0020 National heart and blood vessel
research and demonstration center - Nucleic acid and
protein metabolism in growth and development of heart
(rat)
P50HL-1764804 0026 Study of ischemic heart disease ■
Control of muscle cell proliferation (organ culture)
ROlHL-17973-04 Cultured aortic endothelial cells (human.
cattle, dogs, swine)
ROlHL-1871103 Electrophysiology of heart cells (rats,
chicks)
*• P50HL1919002 0003 Pulmonary SCOR-Pathophysiology.
management of IRDS - Type II cells -Regulation and
differentiation (rat)
ROlHL-19379-03 Characterization of small-granule cells in
the lung (mammals)
139
ROIHL 19669 03 Lung oigiin culture and surfactant
bloiynthesis (adult and letol rati)
POIHL 19717 02 000/ Response ol the lung to ifllury
Callular level itudies ol prostaglandin like molecules
(cattle)
POIHL 197 1 7 07 0023 Response ol the lung to in|ury
Postnatal lung devalopment Cells, connective tissue and
physiology (animals)
POIHL 1971/02 0025 Response ol the lung to Injury
Role ol oxygen in regulation ol lung growth and
development (rats)
POIHL 19/1/0? 0026 Response ol the lung to injury
Protein depletion and postnatal lung development (rats)
POIHL 19/1/02 0028 Response ol the lung to injury
Compensatory growth ol the lung lollowing pneumonectomy
(rabbits)
POIHL 19737 02 0003 Cellular and molecular aspects ol
respiratory physiology Cortisol dependent alterations in
lung type II cells (rats)
ROIHL 1974603 Prolileration and dilterentiation ol
alveolar macrophages (mice, hamsters)
POIHL 20581 01 0002 Vascular neuroellector
mechanisms in health and disease Trophic interaction
between adrenergic nerves and vascular smooth muscle
ROIHL 2070802 Voltage clamp ol embryonic heart cell
aggregates (rat and chick embryos)
ROIHL 20826-02 Megakaryocyte prolileration and its
control (mice)
ROIHL 20859-02 Beta adrenergic catecholamine receptor
ROIHL 2089902 Cellular mechanisms of hemoglobin F
regulation (human)
ROIHL 20902 02 Studies on marginal band system ol
erythrocytes (amphibians, reptiles, lish)
ROlHL-20943-02 Comparision ol microsphere and RBC
behavior in vivo
R23HL-21950-01
disease (human)
ROlHL-22550-02
and hamsters
ROIHL 2266401
Endothelial cell mechanisms in vascular
Genetic cardiomyopathies in salamanders
Smooth muscle development in vitro
Adaptive heart growth in neonates and
Regulation of myocardial cell growth
(rats, guinea pigs)
R23HL-22959-01 Heart development in inherited
cardiomyopathy (hamsters)
" R01HL2301301
(chick embryo)
ROlHL-23025-01
adults (rats)
CEU DIVISION
SEE ALSO GROWTH ABNORMAL, HYPERPLASIA (GENERAL)
SEE ALSO NUCLEIC ACIDS SYNTHESIS, DNA
POlHL-06370-17 0004 Cardiopulmonary and renal
pathology research center ■ Lymphocytes in graft rejection
and immune surveillance (human)
ROIHL 16904-03 Regulation of smooth muscle cells in
arteriosclerosis (rabbit aorta)
POlHL-18645-03 0005 Biology of the artery wall and
atherosclerosis - Effects of atherosclerosis risk factors on
endothelium of the primate
** POlHL-22602-01 0003 Pathophysiology of the
endothelium - Mechanisms of endothelial proliferation
(human, animals)
ROIHL 2288301 Lung epithelial cell interactions in vitro
" ROlHL-23025-01 Adaptive heart grovrth in neonates and
adults (rats)
CEU DIVISION, MITOSIS
SEE ALSO ANTIMITOTIC AGENTS
SEE ALSO MITOGENS
POlHL-06285-18 0179 Cardiovascular-respiratory
physiology and biochemistry - Regulation of myocardial cell
grovrth (rats, chick embryo)
POlHL-15835-06 0010 Study of muscles related to heart
disease - Muscle structure and reaction to injury (mice,
rats)
R01HL16666-05 Micropinocytosis in isolated capillary
endothelium
P50HL-17648-04 0026 Study of ischemic heart disease -
Control of muscle cell proliferation (organ culture)
P50HL-18828-03 0009 Specialized center of research in
thrombosis - Platelet formation and megakaryocyte cell
biology (guinea pig, human)
ROlHL-20826-02 Megakaryocyte proliferation and its
control (mice)
ROlHL-22783-01 Hemodynamic induction of intimal
fibromuscular lesion
CEU DIVISION, SYNCHRONOUS CEU DIVISION
P50HL-19190-02 0003 Pulmonary SCOR-Pathophysiology.
management of IRDS - Type II cells -Regulation and
differentiation (rat)
ROlHL-21329-02 Beta-receptor regulation and cardiac
sites of drug action (cat, guinea pig, rat)
CEU FLUIDS
SEE ALSO BODY FLUIDS (AND RELATED SUBSTANCES)
ROlHL-12421-10 Pathophysiology of circulatory shock
(dogs, baboons)
Regulation of the circulation in
Ion flux alterations in caudal artery in
POIHL-14388-07 0152
pathological states
SHR
P01HL14388-07 0153
pathological states -
(rats)
Cll
ROIHI IHOblOJ Intracellular ionic iclnili*! in htart
mutcle (Irogt)
ROIHI 19000 0] lirtvtriibit myocardial injury (rati)
POIHL 19742 07 0007 Study ol vaicular imoolh rnuKl*
Vascular smooth mutcia rttponit to wrum lipoprolaini
(rati)
ROIHL 70153 0? Intracellular pH and myocardial
electropharmacology Idogt. guinea pigil
ROIHL 20711 01 Structure (unction lelationihipt in fed
cell NA K pumps (goals)
ROIHI 70/25 02 Mechanisms and cellular functions of ion
transport
ROIHL 71498 0? Pathophysiology ol edema (rats, cats)
ROIHL 22261 01 Compliance ol lluid spaces in advancing
hypertension (rats)
CEU FLUIDS, CEU WATER
SEE ALSO BODY FLUID BALANCE, BODY WATER
N01HB62962 0? Red cell distributions in cyanate treated
blood (human, sheep)
P60HL 15157 0/ 0018 Comprehensive center lor sickle
cell disease Red blood cell membrane physiology in sickle
cell anemia (human)
ROIHL 16784 03 Lung tissue and water volume (human,
dogs)
" POIHL 16833 04 0006 Hemoglobin and red cell system in
hemoglobinopathies Role ol water in lunclion ol
hemoglobin and myoglobin (human)
ROIHL 23138 01 Myocardial ischemia (dogs, rats, chick
embryo)
CEU FLUIDS, OSMOTIC PRESSURE
SEE ALSO BODY FLUID BALANCE. OSMOTIC PRESSURE
ROIHL 02363 20 Kinetics of water and electrolytes in
shock (dogs, rats)
ROlHL-04457 20 Cellular aspects of active transport (fish,
rabbits, anurans, turtles)
P01HL06664 17 0010 Cardiopulmonary lunction in
remediable vascular disease - Ischemia and acute renal
lailure (rats)
** POlHL-06664 17 0034 Cardiopulmonary lunction in
remediable vascular disease - Role ol hyperosmolar agents
in ischemic heart disease (dogs)
POlHL-06664-17 0038 Cardiopulmonary lunction in
remediable vascular disease - The dynamics of ADH-
stimulated osmotic water flow
POIHL 12157-11 0060 Functions and mechanisms of cell
membrane ion transport Ion transport and electrical
properties of giant-celled aiga
P60HL- 15999-05 0014 Miami comprehensive sickle cell
center - Biochemical and morphological parameters of
sickle cells (human)
ROlHL-18148-04 Adrenal catecholamine secretion
P01HL18208-04 0001 Center for the study of blood cell
rheology - Physiological basis of reversible erythrocyte
shape change (human, firefly)
ROlHL-20278-02 Cellular mechanisms of renin secretion
(rats)
ROlHL-20652-01 Sites of leakage in pulmonary edema
(dogs)
Sickle cell anemia and other
Kinetics of sickling
Regulation of the circulation in
Subcellular distribution of calcium
P01HL-21016-02 0004
hemoglobinopathies
CELL-FREE SYSTEMS
POlHL-09011-15 0002 A research and resource program
in blood - Biosynthesis of fibrinogen (dogs)
ROlHL-11511-10 Structure ol ferritin and its role in iron
metabolism (horse, rats, human)
R01HL-11906-11 Comparative study of heart function
(cats, rats, hedgehogs, squirrels)
ROlHL-15965-06 Experimental atherosclerosis and elastin
metabolism (chicks)
ROlHL-1 7369-04 Arterial bypass surgery-Structure and
metabolism (monkeys)
ROlHL-20925-01 The acetylation of fetal hemoglobin
(human)
R23HL-2105102 Adrenergic receptors and the adenylate
cyclase system (frog RBC)
ROlHL-23588-01 NOV infection-Analysis at the subcellular
level (chickens)
CEU FUSION (GENERAL)
POlHL-12157-11 0037 Functions and mechanisms of cell
membrane ion transport - Developing structure of heart
cells in tissue culture
R01HL18048-04 Dynamics of artificial and biological
membranes (human)
POlHL-18708-03 0007 Oxygen, energy and contractility in
cardiac tissue - Surfaces, energy requirements, and
contractile proteins of cardiac cell in vitro
POlHL-19259-03 0003 Digoxin-specilic antibody in human
therapy - Synthesis of dogoxin-spccific antibody in
continuous cell culture (human, sheep)
ROlHL-20300-02 Histone H5 and avian erythropoiesis
(chickens, rabbits)
ROlHL-20725-02 Mechanisms and cellular functions of ion
transport
ROlHL-23593-01 Mast cell granules-Structure and
secretion (rats)
CELL GROWTH REGULATION
POlHL-03174-23 0001 Mechanisms of acute vascular
reaction to injury - Response of the vascular intima to
injury (human, rats)
(contd)
•Excludes rautine melhodotogy OR covers only general projects which preclude indexing at the specific level
"Onented significantly to above subject.
M Grant has subprojects descnbmg specific research aspects.
See Appendix for investigator's name and grant number.
CEL
140
CEL
** POlHL-06285-18 0178 Cardiovascularrespiratorv
physiology and biochemistry - Biochemical regulation of
hypertrophy (cats, rabbits)
** POlHL-0628518 0179 Cardiovascular-respiratory
physiology and biochemistry - Regulation of myocardial cell
growth (rats, chick embryo)
POlHL-06285-18 0186 Cardiovascular-respiratory
physiology and biochemistry - Leukocyte hormone receptors
and cyclic nucleotides (tissue culture)
POlHL-06314-17 0054 Immunologic mechanisms in
cardiovascular disease - Physiology of cell communications
(mice, frogs, guinea pigs)
POlHL-1 1414-11 0037 Thrombosis and atherosclerosis
program - Vascular intimal injury and healing (rabbits,
rats)
** P50HL-14147-08 0012 Specialized center of research in
thrombosis - Tissue culture study of arterial cells (human,
hamster)
P50HL- 14147-08 0018 Specialized center of research in
thrombosis - Biochemical aspects of platelet function in
thrombosis and cell growth (human)
P50HL 14212 07 0016 Correlated studies of pulmonary
fibrosis Role of pulmonary alveolar macrophages in
fibrosis (human, rabbit)
P50HL-14230-07 0092 A/S SCOR -Lipids, atherosclerosis
and thrombosis - Tissue lipids -Cell culture studies
(human)
** P50HL-14230-07 0096 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Ultrastructural studies of endothelial cells
(human)
P50HL- 15062-07 0001 Study of lipoproteins, artery wall,
and atherosclerosis - Structure and molecular interactions
of serum lipoproteins (human, monkey)
** P50HL-15062-07 0012 Study of lipoproteins, artery wall,
and atherosclerosis - Lipoprotein stimulation of arterial
smooth muscle cell proliferation (mammals)
POlHL-15835-06 0025 Study of muscles related to heart
disease - Cellular biology of vascular smooth muscle
(guinea pig)
P60HL-17269-04 0020 National heart and blood vessel
research and demonstration center - Nucleic acid and
protein metabolism in growth and development of heart
(rat)
P50HL-17648-04 0026 Study of ischemic heart disease -
Control of muscle cell proliferation (organ culture)
ROlHL-17973-04 Cultured aortic endothelial cells (human,
cattle, dogs, swine)
R01HL-19132-04 Role of zinc transferrin in lymphocyte
transformation (human)
" P50HL-19190-02 0003 Pulmonary SCOR-Pathophysiology,
management of IROS • Type II cells -Regulation and
differentiation (rat)
** ROlHL-20197-02 Maintenance and repair of vascular
endothelium (human, animals)
ROlHL-20391-03 Polydisperse LDL-Structure, metabolism
and function (human)
** ROlHL-20826-02 Megakaryocyte proliferation and its
control (mice)
** P50HL-21006-02 0004 Specialized center of research in
arteriosclerosis - Regulation of growth of human arterial
smooth muscle cells by platelets
ROlHL-21009-02 Effects of air pollutants on lung cells in
culture (rats)
** R23HL-21396-02 Isolation, growth and metabolism of type
1 pneumocytes (rabbits)
** ROlHL-22119-01 Biochemistry of platelet function in
thrombosis and cell growth (rabbits)
ROlHL-22474-01 Cholesterol metabolism and
atherosclerosis (rats, human, rabbits)
** ROlHL-22729-01 Intracellular degradation of newly
synthesized collagen (human, chick, rabbit)
** R01HL-23626-01 A study of the regulation of myocardial
hypertrophy (rats)
ROlHL-23969-01 Surfactant synthesis by type II cells in
vitro (rats)
CEU GROWTH REGULATION, CHALONES
ROlHL-20826-02 Megakaryocyte proliferation and its
control (mice)
CEU GROWTH REGULATION, CONTACT
INHIBITION
ROlHL-20197-02 Maintenance and repair of vascular
endothelium (human, animals)
CEU HYBRIDS
P01HL-09011-I5 0010 A research and resource program
in blood - Chromosome changes in human genetics
ROlHL-15026-12 Quantitative genetic control of protein
synthesis (human, primates, mammals)
P60HL 16008-06 0018 Wayne Slate University
comprehensive sickle cell center - Hemoglobin S and RBC
membranes -Pathogenesis of irreversibly sickled cells
ROlHL-18876-03 Human alpha-1-antitrypsin synthesis in
vitro
ROlHL-20300-02 Histone H5 and avian erythropoiesis
(chickens, rabbits)
POlHL-20948-02 0004 Molecular basis of cholesterol
metabolism Genetic analysis of the LDL pathway (human)
P01HL21016-02 0003 Sickle cell anemia and other
hemoglobinopathies - Role of non S hemoglobin in gelation
and sickling
POlHL-210 16-02 0012
hemoglobinopathies
permanent cell line
Sickle cell anemia and other
Stimulation of Hb F synthesis in a
CELL HYBRIDS, HETEROKARYON
ROlHL-20300-02 Histone H5 and avian erythropoiesis
(chickens, rabbits)
CELL INCLUSION BODIES
** POlHL-16137-05 0013 Alveolar biology • Development and
pathology of surfactant -Formation of alveolar (rabbits,
sheep)
ROlHL-16725-03 Physiological regulation of pulmonary
surfactant (dogs, rats)
P50HL-19187-02 0003 Pediatric pulmonary SCOR-Hyaline
membrane disease • Hyaline membrane disease-
Ultrastructure studies (monkey)
** P50HL-19187-02 0004 Pediatric pulmonary SCOR-Hyaline
membrane disease - Hyaline membrane disease-Surface
active material, lamellar bodies (mice, rats)
CELL INGESTION, PHAGOCYTOSIS
SEE ALSO CELL DESTRUCTION, AUTOPHAGY
SEE ALSO CELLS, PHAGOCYTES
POlHL-03 174-23 0005 Mechanisms of acute vascular
reaction to injury - Renal small vessel didease -Cell and
matrix response (human, mice)
POlHL-06314-17 Immunologic mechanisms in
cardiovascular disease
M
POlHL-063 14-17 0046
cardiovascular disease
(human, mice)
POlHL-06314-17 0052
cardiovascular disease
Immunologic mechanisms In
Mediators of immune injury
Immunologic mechanisms in
Role of cyclic nucleotides in
neutrophil function (human)
POlHL-063 14-17 0060 Immunologic mechanisms in
cardiovascular disease - Strept antigens and infections in
cardiovascular complications (human, animals)
POlHL-063 14-17 0062 Immunologic mechanisms in
cardiovascular disease - Immunologic renal vascular
disease (human, animals)
ROlHL-06481-15 Lipid metabolism (human, rats)
ROlHL-07652-14 Destruction of red blood cells in
hemolytic anemias (human, guinea pigs)
ROlHL-09125-14 Ultrastructural cytochemistry (human,
chick)
ROlHL-11880-10 Physiology and pathology of blood
platelets (human, dogs)
ROlHL-12766-09 Structure-function relation of blood
vessels (rats, monkeys)
R01HL-13885-08 0007 Cystic fibrosis and pulmonary
disease - Alveolar macrophage defense mechanism
(human, rabbits)
ROlHL-13885-08 0008 Cystic fibrosis and pulmonary
disease - Pseudomonas specific activation of alveolar
macrophages (human, rabbits)
P50HL-142 12-07 0006 Correlated studies of pulmonary
fibrosis - Alveolar macrophage physiology (human, rodents,
rabbits)
P50HL14212-07 0007 Correlated studies of pulmonary
fibrosis - Protein metabolism in alveolar macrophages
(rabbits, guinea pigs, human)
P50HL-1421207 0013 Correlated studies of pulmonary
fibrosis - Mechanism of beryllium pathogenicity in the lung
(human, rabbit, guinea pig)
P50HL-1421207 0014 Correlated studies of pulmonary
fibrosis - Pulmonary lavage cells, secretions in diffuse
intersititial lung disease (human)
P50HL- 142 12-07 0015 Correlated studies of pulmonary
fibrosis - Pulmonary defense mechanisms and fibrotic lung
disease (rodents, rabbits)
P50HL-142 12-07 0016 Correlated studies of pulmonary
fibrosis - Role of pulmonary alveolar macrophages in
fibrosis (human, rabbit)
P50HL14230-07 0092 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Tissue lipids -Cell culture studies
(human)
ROlHL-14262-07 Leukocyte proteases and their lung
targets (human, dogs, rabbits)
P50HL-15061-07 0007 Response of lung to injury -
Human factors for phagocytosis in normal and diseased
lungs
P50HL-15061-07 0009 Response of lung to injury ■
Alveolar macrophages (human, rabbits)
P50HL-15092-07 0006 Immune and fibrotic response to
occupational environments - Immunologic studies in
silicosis (human, rabbits, hamsters, guinea pigs)
P60HL-1516007 0014 Center for sickle cell disease •
Replacement therapy of opsonin deficiency in sickle cell
anemia (children)
P60HL-151 69-05 0009 Support for center for sickle cell
disease - Infections in sickle cell anemia (human)
P60HL15999-05 0008 Miami comprehensive sickle cell
center - Cyanate effect on host defense-Cellular and
humoral (human, guinea pig, rabbits)
P60HL16005-05 0020 Comprehensive sickle cell center ■
Studies of the immunologic defect in sickle cell anemia
(human)
POlHL-161 18-06 0004 Study of emphysema - Metabolic
activity of pulmonary connective tissue (human, hamsters)
P01HL16748-05 0001 Cellular and Immunological basis
of pulmonary diseases - Mechanisms of alveolar
macrophage function and dysfunction (human, rabbits)
POlHL-16748-05 0004 Cellular and immunological basis
of pulmonary diseases - Cellular and immunological
processes in pulmonary defense systems
POlHL-16769-05 0004 Pathobiologic and host defense
reactions in the lung • Pathogenesis of Pseudomonas and
Serratia pneumonias (rabbits)
POlHL-16769-05 0008 Pathobiologic and host defense
reactions in the lung - Pulmonary immunocytologic defense
mechanisms against bacteria (human, animals)
ROlHL-16952-05 Cardiovascular pathology (rats, rabbits)
P60HL-17265-04 0009 Community blood resource center
support ■ Research-Developing granulocyte transfusion
therapy (human, rabbit)
ROlHL-1743703 'Perfusion lung'-Role of traumatized
leukocytes (dogs, human)
ROlHL-17596-03 Leukocyte-endothelial interactions (rats)
RO1HL-I8OO2-03 Circulatory shock, trauma and RE-system
function (rats)
ROIHL- 18284-04 Aging erythrocytes-Bio-recognition and
elimination (monkeys)
ROlHL-18731-02 RES stimulating materials in
experimental shock (dogs)
P50HL-18828-03 0002 Specialized center of research in
thrombosis Endothelial cell biology (human, guinea pig)
P50HL-I9171-02 0007 Pulmonary SCOR-Lung injury by
childhood infections - Immunologic studies in models of
lower respiratory tract infection (rodents)
P5OHL1917102 0009 Pulmonary SCOR-Lung injury by
childhood infections - Host-parasite interaction-Scanning
electron microscopy, freeze-fracture methods
ROlHL-19237-03 Obstructive lung disease and alveolar
macrophages (human, animals)
ROlHL-19429-03 Phagocytosis-lngestion in alveiolar
macrophages (rabbits)
R23HL-19584-01 Alveolar macrophage responses to toxic
particle exposure (guinea pigs, human)
ROlHL-19628-03 Mechanisms of pulmonary alveolar
proteinoses (human, rats)
ROlHL-19633-02 Pathogenesis and pharmacology of lung
fibrosis (rats, rabbits)
R01HL19685-03 Pathogenesis of inflammation of the lung
(guinea pigs)
R01HL19746-03 Proliferation and differentiation of
alveolar macrophages (mice, hamsters)
RO1HL-I9760-01 Cellular immune responses of the lung
(mice, guinea pigs)
ROlHL-19777-03 Regulation of hypersensitivity in the lung
(rats, guinea pigs, rabbits, human)
ROlHL-20002-03 Pulmonary complications of viral
infections (children)
ROlHL-20086-02 Circulatory control of splenic function
(rats)
ROlHL-20125-02 Cyclic nucleotides and alveolar
macrophage activation (rabbits)
ROIHL-2031402 Host defense against S pheumoniae in
sickle cell disease (human)
ROlHL-20352-02 Defenses of lung cells against oxygen
toxicity (human, animals)
Pathogenesis of rheumatic fever (human,
'Excludes routine methodology OR covers only general projects which preclude
**Onented significantly to above subject.
ROlHL-20533-09
rabbits)
ROlHL-20675-02 Alveolar macrophage function in man
P60HL-20985-01 0002 Northern California sickle cell
center - Immunization with polyvalent pneumococcal
polysaccharide vaccine (human)
POlHL-20993-02 0006 Population dynamics of arterial
cells in atherogenesis - Mechanism of regression of
atherosclerosis by diet and injury (swine)
R23HL-21089-02 Localization of mediators in dispersed
lung cells (guinea pigs, human)
R23HL-21116-02 Mechanisms of membrane and tissue
damage in lung (dogs, rabbits)
ROlHL-21120-02 Membrane dynamics in alveolar
macrophages (rabbits)
R23HL-21 134-02 Immune function and fibrogenesis in
silicosis (guinea pigs)
** ROlHL-21140-01 Studies of pulmonay alveolar
macrophage function (rabbits)
ROlHL-22029-02 Bronchopulmonary resistance to bacterial
infection (mice)
ROlHL-22302-01 Immune responses in the human lung
(also rabbits, monkeys)
" ROlHL-22671-01 Removal of senescent and stored human
red cells
R23HL-22823-01 Phagocytic and immune defense
mechanisms of the lung (mice)
R23HL-22895-01 Smoke inhalation-Biochemical and
cellular responses (rabbits, bacteria)
ROlHL-22996-01 Venom proteases -Action on plasma
protease inhibitors (human)
CELL INTERACTION
SEE CELL-CELL INTERACTION
CELL LINES, BANKS AND REGISTRIES
SEE TISSUE (CELL) CULTURE, CELL CULTURE COLLECTIONS
BANKS AND REGISTRIES
CELL MEDIATED HYPERSENSITIVITY
SEE HYPERSENSITIVITY, DELAYED HYPERSENSITIVITY
CELL MEMBRANE
SEE CELL COMPONENTS, CELL MEMBRANE
(contd)
ndexing at the specific level.
M Grant has subprojects describing specific research aspects
See Appendix for investigator's name and grant number.
CEL
CELl MIORATION
Sit ALSO NtOPLASIIC CROWIM. NfOPlASMS MtlASIASIS
•• P01HL031M 23 0001 Mechanisms ol ttulo vascul«i
rMction to inlury R«spons< ot the vtsculai inlima to
injunf (human, (ats)
P01HL031M?3 OOOS Mechanisms ot acute vasculdi
leaction to in|uiy Renal small vessel didease Cell and
matn> response (human, mice)
POIHI 03174 7i 0006 Mechanisms ol acute vascular
reaction to injury Atherosclerotic plaque studies using
mosaic analysis (human)
PSOHl 14212 07 0016 Correlated studies ol pulmonary
librosis Role ol pulmonary alveolar macrophages in
librosis (human, rabbit)
POIHL 16387 04 0003 Ibe blood vessel and
thrombogenesis Blood vessel healing (rabbits)
POIHI 16387 04 0004 The blood vessel and
thrombogenesis Analysis ol vascular basement membrane
by enzymatic methods (human)
ROIHL 17437 03 Perfusion lung' Role ol traumatized
leukocytes (dogs, human)
•* ROIHL 17596-03 Leukocyte endothelial interactions (rats)
ROIHL 1913603 Mucopolysaccharide metabolism in
cardiac anomalies (rats)
ROIHL 19777 03 Regulation ol hypersensitivity m the lung
(rats, guinea pigs, rabbits, human)
ROIHL 20132 03 Histogenesis and biochemistry ol
embryonic lung (birds)
*• R23HL 2195001 Endothelial cell mechanisms in vascular
disease (human)
ROlHL-21988-01
chemotaxis
ROIHL 2278401
Biochemistry ot human platelet
Ductus arteriosus closure -An arterial
lesion model (rabbits)
CEU MOVEMENT
SEE ALSO CELL COMPONENTS. CILIARY MOVEMENT
SEE ALSO CELL MIGRATION
ROlHL-0912514 Ultrastructural cytochemistry (human,
chick)
** POlHL-15835-06 0004 Study of muscles related to heart
disease - Actomyosin systems and cell motility (slime
molds, human)
P01HL16769-05 0002 Pathobiologic and host defense
reactions in the lung Pathogenesis of complement
dependent injury to the lungs (rabbits)
POlHL-18208-04 0001 Center for the study of blood cell
rheology - Physiological basis of reversible erythrocyte
shape change (human, firefly)
POIHL- 18208-04 0002 Center for the study of blood cell
rheology - Holography ol RBC shape (human)
POlHL-18208-04 0003 Center for the study of blood cell
rheology - Bone marrow microcirculation (rats, mice)
** POlHL-18208-04 0005 Center for the study of blood cell
rheology RBC delormability and capillary flow
interrelations (human, mice)
** POlHL-18208-04 0006 Center for the study of blood cell
rheology - Analysis of flow in arterioles and capillaries
(human)
ROlHL-19429-03 Phagocytosls-lngestion in alveiolar
macrophages (rabbits)
R01HL-19633-02 Pathogenesis and pharmacology of lung
fibrosis (rats, rabbits)
R23HL-21805-01 Tissue cell interactions with vascular
prostheses (human, rats, mice)
ROlHL-22455-01 Platelet concentration in the marginal
layer (dogs, human)
CEU NUCLEUS
SEE CELL COMPONENTS. CELL NUCLEUS
CEU POPULATION STUDIES
SEE POPULATION STUDIES CELL
CEU SEPARATION AND COUNTING
SEE CELL SORTING
CEU SORTING
SEE ALSO BLOOD CELL DEPLETION THERAPY. LYMPHOCYTE
DEPLETION
SEE ALSO BLOOD CELL DEPLETION THERAPY. T LYMPHOCYTE
DEPLETION
SEE ALSO BLOOD TREATMENT. LEUKAPHERESIS
SEE ALSO BLOOD TREATMENT. PLASMAPHERESIS
P01HL-06285-18 0209 Cardiovascular-respiratory
physiology and biochemistry - Metabolic studies of isolated
lung cells (human, animals)
P50HL-142 12-07 0014 Correlated studies of pulmonary
fibrosis - Pulmonary lavage cells, secretions in diffuse
intersititial lung disease (human)
ROlHL-16582-05 Artificial lungs (dogs)
ROlHL-18725-03 Light-scattering studies of the sickling
process (human)
** POlHL-19737-02 0014 Cellular and molecular aspects of
respiratory physiology - Cell separation facility
" ROlHL-2078802 Preservation of human platelets for
transfusion
CEU STORAGE DISORDERS
SEE MCTABOLIC DISORDERS INBORN. LYSOSOMAL
DISORDERS
CEU SURFACE ACTIVITY (GENERAL)
SEE MEMBRANE SURFACE (BIOLOGICAL) ACTIVITY (GENERAL)
141
CELL TYPES
Sli Also Ctll UIIMNINIIAIION
•■ ROIHI 02063 23 Uioihcmiitry rtnd lunctlon ol lipids and
cell membmnes (humnn, yeiisl. animals)
POIHL 031 74 23 0U02 Mechanisms ol acute vascular
reaction to injury Chemical struiiuro. pathological
significance ol amyloid substance (human, mice)
POIHL 031 74 23 0005 Mechanisms ol acute vascular
reaction to injury Renal small vessel didease Cell and
matrix response (human, mice)
POIHL 031 74 23 0006 Mechanisms ol acute vascular
reaction to injury Atherosclerotic plaque studies using
mosaic analysis (human)
POIHL 06285 18 0182 Cardiovascular respiratory
physiology and biochemistry Structure and lunction ol
vascular chemoreceptors (cats, rats)
** P01HL06285 18 0209 Cardiovascular respiratory
physiology and biochemistry Metabolic studies ol isolated
lung cells (human, animals)
POIHL 063 14 17 0050 Immunologic mechanisms in
cardiovascular disease Physiologic changes in
lymphocytes (human, mice)
POIHL 06314 17 0054 Immunologic mechanisms in
cardiovascular disease Physiology of cell commur\ications
(mice. Irogs. guinea pigs)
** P01HL06314 17 0063 Immunologic mechanisms in
cardiovascular disease Glomerular cells in tissue culture
(human)
POlHL-06314-17 0066
cardiovascular disease
Immunologic mechanisms in
Sensitization, cell mediated
cytotoxicity, role ol lymphocytes (human, mice)
POIHL- 12 157 11 0055 Functions and mechanisms of cell
membrane ion transport Growth and development of
synthetic strand heart cells in culture (chick embryo)
ROlHL-14663-07 Pulmonary oxygen toxicity in newborn
lung (human, mice)
P01HL-15832-06 0002 Chemical-structural predispositions
to lung injury - Connective tissue in lung in development
and repair ol injury (human, rats, mice)
POlHL-1583206 9001 Chemical-structural predispositions
to lung injury - Tissue culture studies ol lung cell tunction-
■Core facility
POlHL-161 17-05 0001 Ion movements and membranes in
cardiovascular control - Developmental studies of
contractile cell junctions (rats, rabbits, elasmobranch)
ROlHL-16240-05 The cardiac histamine receptor (rabbits.
guinea pigs)
ROlHL-16330-06 Aging-tissue injury and repair (rats)
POlHL-164 11-04 0005 Blood systems in coagulation and
vessel disease - Chemical analysis of serum components
associated with coagulation (human, animal)
ROlHL-1671105 RBC and endothelial membrane material
characteristics (human)
ROlHL-16920-02 Proteases in normal and immunologically
injured lung (guinea pigs, rabbits)
POlHL-17430-05 0008 Control of coagulation - Cultures
of von Willebrand endothelial cells (pigs)
ROlHL-18181-04 Surfactant metabolism-Alveolar cells and
lung disease (mice, rabbits)
ROlHL-19009-03 Morphometric analysis of the sinoatrial
node (ferret)
P50HL191 70-02 0005 Harvard pulmonary SCOR -Chronic
diseases of the airways • Pulmonary toxicology of plastics
intermediates and pyrolysis products (animal)
ROlHL-19419-03 Cellular interactions with foreign
materials (mammals)
P01HL197 17-02 0002 Response of the lung to injury -
Prolyl hydroxylase, lysyl hydroxylase and lung collagen
biosynthesis (rabbits)
POlHL-1973702 0003 Cellular and molecular aspects of
respiratory physiology - Cortisol-dependent alterations in
lung type II cells (rats)
ROlHL-19779-03 Biochemical basis of oxygen damage to
lung cells (guinea pigs, rats)
ROlHL-19806-03 Chemotactic control of airway phagocytes
(human, rabbits)
ROlHL-2019702 Maintenance and repair of vascular
endothelium (human, animals)
ROlHL-20344-02 Regulation of protein turnover in lung
tissue (rats)
POlHL-205 52-02 0010 The development and regression of
cardiac hypertrophy - Energy metabolism in the
hypertrophied heart animals
ROlHL-20566-02 Lactate metabolism in the lung (rats)
ROlHL-20878-02 Cellular aspects of lung injury (rats.
rabbits)
POlHL-20948-07 0002 Molecular basis ol cholesterol
metabolism - LDL pathway in cell lines with informative
properties other than fibroblasts
R23HL-21042-01 Cardiopulmonary reflexes and their
anatomical basis (dogs)
ROlHL-21568-02 Cell biology of the alveolar-capillary unit
(animals)
ROlHL-21665-01 Collagen polymorphism and arterial
structure (monkeys, guinea pigs)
ROlHL-2207901 Heart receptor sites for digitalis and
steroid hormones (animals)
ROlHL-22266-01 Production of proteases by lung cells in
culture (human, rodents, rabbits, sheep)
ROlHL-22289-01 Endothelial cell mediated fibrinolysis
(rabbits)
CEL
ROIHI 774 70 01 lipoiomi myocardial uplat* in inl<i<.l
and ischemia (dogi. rati, mice)
ROIHI 774/4 01 Choleiterol mutabolnm and
alhero\(li>ru'in (nil humnn rahbiti)
POIHI 77607 01 0001 Pitllioph»MOlo|y ol lh«
endothelium Platelet endothelial interaction-, in vitro
(human, cattle)
POIHL 77607 01 0003 Pathophysiology ol the
endothelium Mechanisms ol (ndothtliil prollltrition
(human, animals)
ROIHI 77739 01 Evolution and progression ol pediatric
atherosclerosis
ROIHI 77783 01 Hemodynamic induction ol intimal
libromuscular lesion
R23HL 77839 0! Cellular translation ol liposomally
delivered mRNA (human, mammals)
ROIHL 27974 01 The airway mucosal barrier (guinea pigs)
ROIHL 23626 01 A study ol the regulation ol myocardial
hypertrophy (rats)
ROIHL 23899 01 flow and Hexing at blood/biomaterial
intertaces
CELl VOLUME
** ROIHL 04457 20 Cellular aspects ol active transport dish.
rabbits, anurans. turtles)
M P01HL06664 17 Cardiopulmonary lunction in remediable
vascular disease
POlHL-06664 17 0034 Cardiopulmonary function in
remediable vascular disease Role ol hyperosmolar agents
in ischemic heart disease (dogs)
POIHL 06664 17 0036 Cardiopulmonary function in
remediable vascular disease In vitro studies on the
mechanism ol ischemic damage to cells (rabbits)
POlHL-06664-17 0037 Cardiopulmonary function in
remediable vascular disease Salt and water balance of
cells and tissues (rabbits)
** POlHL-06664-17 0039 Cardiopulmonary function in
remediable vascular disease Transepithelial active
transport and cell volume regulation (frogs)
** POlHL-08682-15 0036 Regulation of the cardiovascular
system Electrolyte transport in myocardium with
hemorrhagic shock (rats)
ROlHL-0936414 Ion transport by heart mitochondria
(cattle, rat. rabbit)
** POlHL-12157-11 0049 Functions and mechanisms ol cell
membrane ion transport - Ouabaininsensitive cation
transport in duck red cells
POlHL-12157-11 0056 Functions and mechanisms ol cell
membrane ion transport - Isotopic fluxes in synthetic
strands of heart cells (chick embryo)
POlHL-12157-11 0060 Functions and mechanisms of cell
membrane ion transport ■ Ion transport and electrical
properties of giant-celled aiga
ROlHL-13567-06 Ion transport across cell membranes
(human)
ROlHL-14713-06 Hypothermia and the heart (bats, guinea
pigs)
P60HL-15162-07 0019 Comprehensive sickle cell center
RBC-Blood rheology in sickle cell anemia and related
disorders (human, animal)
ROlHL-15888-05 Comparative stereology of the
myocardium (birds, mammals)
P60HL- 15999-05 0014 Miami comprehensive sickle cell
center - Biochemical and morphological parameters of
sickle cells (human)
POlHL-151 17-05 0001 Ion movements and membranes in
cardiovascular control - Developmental studies of
contractile cell junctions (rats, rabbits, elasmobranch)
P50HL-17670-04 0023 Study of ischemic heart disease -
Energy metabolism in acute myocardial ischemic injury
(dogs)
ROlHL-18038-03 Structure and function of heart
mitochondria (cattle)
ROlHL-18256-01 Optical properties of platelets and
erythrocytes (rabbits, dogs, human)
ROlHL-19000-03 Irreversible myocardial injury (rats)
POlHL-20592-02 0010 Cell biology of cardiac and
skeletal muscle - Mitochondrial genesis during myocardial
cell hypertrophy and hyperplasia (rats)
ROlHL-20725-02
transport
Mechanisms and cellular functions of ion
Megakaryocyte proliferation and its
ROlHL-20826-02
control (mice)
** ROlHL-2117901 Volume regulation-Role of the membrane
potential (amphiuma)
ROlHL-2152502 Effect of cations, anions and water upon
blood vessels (dogs, rats)
ROlHL-2199301 Hypertensive hypertrophy-Effects of
cardiac mechanics (rats)
ROlHL-22281-01 Microprobe analysis and metabolite
levels of ischemic mycardium (dogs)
ROlHL-23138-01 Myocardial ischemia (dogs, rats, chick
embryo)
CELL WALL
SEE CELL COMPONENTS, CELL WALL
CELL WATER
SEE CELL FLUIDS, CELL WATER
CELLS
SEE ALSO BLOOD AND RE SYSTEM, MAST CELLS
SEE ALSO BLOOD AND RE SYSTEM, MEGAKARYOCYTES
SEE ALSO BLOOD CELLS
(contd)
'Excludes routine methodok>gy OR covers only eeneral projects which preclude indexing at the specific level.
''Onented significantly to above subject.
M Grant has subprojects descnbing specific research aspects-
See Appendix for investigator's name and grant number.
• ' •arj£» JUVW# J^LMifJ
CEL
142
CER
SEE ALSO BRAIN CELLS
SEE ALSO CONNECTIVE TISSUE CELLS
SEE ALSO CYTOLOGY (GENERAL) SEE ALSO CELL...CYTO ..*
SEE ALSO HEART CELLS
SEE ALSO KIDNEY CELLS
SEE ALSO LIVER CELLS
SEE ALSO MUSCLE CELLS
SEE ALSO NEOPLASTIC CELLS
SEE ALSO NERVOUS SYSTEM, NEUROGLIA
SEE ALSO NERVOUS SYSTEM, NEURONS
SEE ALSO PIGMENTATION, CHROMATOPHORES
SEE ALSO TISSUE (CELL) CULTURE, CLONE CELLS*
** P01HL-U41407 0014 Environmental influences on
cardiorespiratory and cellular functions - Temperature and
acid-base status in tissues, cells, and subcellular system
CEUS, PHAGOCYTES
SEE ALSO BLOOD AND RE SYSTEM, MACROPHAGES
SEE ALSO BLOOD CELLS, LEUKOCYTES
SEE ALSO CELL INGESTION, PHAGOCYTOSIS
R01HL19684-03 Histotypic lung cultureincircumfusion
systems (mice)
ROlHL-19779-03 Bioctiemical basis of oxygen damage to
lung cells (guinea pigs, rats)
** R01HL1980603 Chemotactic control of airway phagocytes
(human, rabbits)
CEUS, SINGLE CELL ANALYSIS
POlHL-11310-12 0087 Mechanisms of cardiovascular
disease - Electrophysiology and electropharmacology of the
heart (dogs)
P01HL-1135M2 0005 Cellular and molecular
mechanisms of myocardial function - Electrophysiology of
cardiac muscle (rats)
R01HL14523-07 Generation and regulation of force in
smooth muscle (animals)
P01HL18208-04 0001 Center for the study of blood cell
Theology - Physiological basis of reversible erythrocyte
shape change (human, firefly)
P01HL-18708-03 0C05 Oxygen, energy and contractility in
cardiac tissue - Cytosolic calcium homeostasis and
bioenergetics of cardiac tissue (animals)
R01HL-18711-03 Electrophysiology of heart cells (rats,
chicks)
RC1HL-19299-03 Myoglobin and oxygen supply to heart
and muscle cells (rats, pigeons)
R01HL19848-02 Contractile activation by rapid
temperature jumps (frogs)
** R23HL-2 1396-02 Isolation, grovith and metabolism of type
1 pneumocytes (rabbits)
ROlHL-22418-01 Neural control of cardio-respiratory
function (cats)
ROlHL-23588-01
level (chickens)
ROlHL-23614-02
muscle (mollusks)
NOV infection-Analysis at the subcellular
Pharmacology of relaxation in smooth
CEUS (ORGANISMS), EUKARYOTIC (SEE ALSO
SPECIFICS)
** P01HL-0901 1-16 0009 A research and resource program
in blood - Control of RNA synthesis in nucleated cells
(yeast, ascites cell)
R23HL-22839-01 Cellular translation of liposomally-
delivered mRNA (human, mammals)
CEUULAR ANALOG OF HUMORAL SENSITIZING
ANTIBODIES
SEE HYPERSENSITIVITY, SENSITIZING ANTIBODIES NON-
HUMORAL
CEUULAR ANTIBODIES NON-HUMORAL
SEE HYPERSENSITIVITY, SENSITIZING ANTIBODIES NON-
HUMORAL
CELLULAR IMMUNITY
SEE IMMUNITY, CELLUUR IMMUNITY (GENERAL)
CENTERS
SEE BIOMEDICAL ENGINEERING, INSTRUMENTATION CENTERS
SEE BLOOD PRESERVATION, BLOOD BANKS, CENTERS-
RESOURCES-REGISTRIES
SEE CLINICAL RESEARCH CENTERS
SEE COMPUTER CENTERS
SEE INFORMATION SYSTEMS (INCL BANKS AND CENTERS)
SEE STATISTICAL SERVICE AND CENTERS
CENTRAL NERVOUS SYSTEM
SEE NERVOUS SYSTEM CENTRAL
CENTRAL NERVOUS SYSTEM DISORDERS
SEE NERVOUS DISORDERS CENTRAL (GENERAL)
CENTRAL SPACES, BRAIN
SEE BRAIN, CENTRAL SPACES
CENTRALLY ACTING DRUGS
SEE NEUROPHARMACOLOGICAL AGENTS, CENTRALLY ACTING
DRUGS (GENERAL)
CENTRIFUGATION
SEE PHYSICAL SEPARATION, CENTRIFUGATION*
CERAMIDE
SEE SPHINGOLIPIDS, CERAMIDE
CERAMIDE DIHEXOSIDES
SEE GLYCOSPHINGOLIPIDS, CERAMIDE DIHEXOSIDES
CERAMIDE TRIHEXOSIDES
SEE GLYCOSPHINGOLIPIDS, CERAf^llDE TRIHEXOSIDES
CERAMIDES
SEE SPHINGOLIPIDS, CERAMIDE
CERCOCEBUS
SEE MAMMALS, PRIMATES, MONKEYS AND APES
(ANTHROPOIDS, NON-HUMAN), OLD WORLD MONKEYS
(CATARRHINES)*
CERCOPITHECUS
SEE MAMMALS, PRIMATES, MONKEYS AND APES
(ANTHROPOIDS, NON-HUMAN), OLD V^ORLD MONKEYS
(CATARRHINES)*
CEREBELLAR DISORDERS
SEE BRAIN DISORDERS, CEREBELLAR DISORDERS
CEREBELLAR NUCLEI
SEE BRAIN, CEREBELLAR NUCLEI
CEREBELLECTOMY
SEE BRAIN LESIONS SURGICAL. CEREBELLECTOMY
CEREBELLUM
SEE BRAIN. CEREBELLUM
CEREBRAL ANEURYSM
SEE CEREBROVASCULAR DISORDERS, CEREBRAL ANEURYSM
CEREBRAL ARTERIES
SEE CEREBROVASCULAR SYSTEM, CEREBRAL ARTERIES
CEREBRAL CIRCULATION DYNAMICS
SEE CEREBROVASCULAR SYSTEM, CEREBRAL CIRCULATION
CEREBRAL CORTEX
SEE BRAIN, CEREBRAL CORTEX
CEREBRAL DEATH
SEE DEATH. CEREBRAL
CEREBRAL DOMINANCE
SEE BRAIN INTERHEMISPHERIC ACTIVITY. CEREBRAL
DOMINANCE
CEREBRAL HEMORRHAGE
SEE CEREBROVASCULAR DISORDERS, CEREBRAL
HEMORRHAGE
CEREBRAL HYPOXIA
SEE CEREBROVASCULAR DISORDERS, BRAIN ISCHEMIA AND
HYPOXIA
CEREBRAL SCLEROSIS DISSEMINATED
SEE NERVOUS DISORDERS, MYELINOPATHIES, MULTIPLE
SCLEROSIS
CEREBRAL VENTRICLES
SEE BRAIN, CENTRAL SPACES, CEREBRAL VENTRICLES
CEREBROANGIOGRAPHY
SEE CEREBROVASCULAR VISUALIZATION,
CEREBROANGIOGRAPHY*
CEREBROARTERIAL OCCLUSIONS AND
THROMBOSIS
SEE CEREBROVASCUUR DISORDERS, CEREBRAL
OCCLUSIONS AND THROMBOSIS
CEREBROARTERIAL OCCLUSIONS
EXTRACRANIAL
SEE CEREBROVASCULAR DISORDERS, CEREBROARTERIAL
OCCLUSIONS EXTRACRANIAL
CEREBROCUPREIN
SEE METALLOPROTEINS, CYTOCUPREINS
CEREBRO-HEPATO-RENAL SYNDROME
(ZELLWEGER SYNDROME)
SEE METABOLIC DISORDERS INBORN, CEREBRO-HEPATO-
RENAL SYNDROME
CEREBROSIDE TRIHEXOSIDES
(AMINOGLYCOLIPID)
SEE GLYCOSPHINGOLIPIDS, CERAMIDE TRIHEXOSIDES
CEREBROSPINAL FLUID
SEE NERVOUS SYSTEM CENTRAL, CEREBROSPINAL FLUID
CEREBROSPINAL FLUID FLOW
SEE NERVOUS SYSTEM CENTRAL, CEREBROSPINAL FLUID
FLOW
CEREBROSPINAL FLUID PRESSURE
SEE NERVOUS SYSTEM CENTRAL, CEREBROSPINAL FLUID
PRESSURE
CEREBROTENDINOUS XANTHOMATOSIS
SEE LIPOGRANULOMATOSES, CEREBROTENDINOUS
XANTHOMATOSIS
CEREBROVASCULAR ACCIDENTS
SEE CEREBROVASCULAR DISORDERS, STROKE
CEREBROVASCULAR DISORDERS
SEE ALSO EYE CIRCULATORY DISORDERS
RC1HL-01979-22 Arteriosclerosis in zoo animals on
controlled diets (animals)
** PC1HL-07896-15 0019 Environmental biomedical research
program - Hyperoxic myopia (human)
** POlHL-07896-15 0055 Environmental biomedical research
program - Cerebral blood flow by Xenon-133 inhalation
(human)
** POlHL-10342-13 0019 The integrated function of
respiration and circulation - Cerebral circulation and
metabolism (dogs)
POlHL-13851-ie Cyclotron produced isotopes in biology
and medicine (human, animals)
** ROlHL-18590-03 Cerebral blood flow after cardiac arrest
(dogs, monkeys)
P50HL-18828-03 0005 Specialized center of research in
thrombosis - Platelet inflammatory factors in thrombosis
(human, guinea pig)
** ROlHL-20500-02 Diabetic human brain microvascular
basement membrane (human)
** R13HL-20765-01 Eleventh Princeton Conference on
Cerebrovascular Disease (new Jersey)
ROlHL-21010-02 Glycemia, other traits and CV death in
40,000 persons
ROlHL-21260-02 Risk factor relationships of
atherosclerosis (monkeys)
NOlHV-53029-04 Nonhuman primate models of
atherosclerosis
NOlHV-53030-05 Nonhuman primate models of
atherosclerosis and hypertension
N01HV-53031-04 Nonhuman primate models of
atherosclerosis and hypertension
N01HV-62905-02 Non-human primate models of
arteriosclerosis
NOlHV-72978-02 Development of models of hypertension
NOlHV-72980-02 Development of models of hypertension
CEREBROVASCULAR DISORDERS, BRAIN
ISCHEMIA AND HYPOXIA
SEE ALSO CEREBROVASCULAR DISORDERS, CEREBRAL
OCCLUSIONS AND THROMBOSIS
SEE ALSO CEREBROVASCULAR DISORDERS,
CEREBROARTERIAL OCCLUSIONS EXTRACRANIAL
SEE ALSO NEUROLOGIC MANIFESTATIONS, SYNCOPE
R01HL-00487-29 Vasomotor tone and venous return
(human, dogs, monkeys )
POlHL-06285-18 0147 Cardiovascular-respiratory
physiology and biochemistry - Metabolic regulation of
cerebral microcirculation (cats)
** POlHL-07896-15 0052 Environmental biomedical research
program - Effects of hypoxia on cerebral function
** POlHL-08899-14 0008 Tolerance to respiratory gases in
health and disease - Hypoxia in regards to respiratory and
brain circulatory control (goats)
POlHL-14985-07 0003 Adaptation to hypoxia - Hypoxia
and oxygen transport (human, dogs)
** ROlHL-16022-05 Determinants of the ventilatory response
to hypoxia (goats, cats)
P01HL-18974-03 0001 Experimental neurogenic
hypertension program - Central neural systems regulating
arterial pressure (rabbits)
P50HL-19187-02 0011 Pediatric pulmonary SCOR-Hyaline
membrane disease - Effects of hypoxia and hypercapnia on
developing nervous system (monkey, human)
** P50HL-19190-02 0007 Pulmonary SCOR-Pathophysiology,
management of IRDS - Asphyxia-Cerebral metabolism (dog,
rat)
ROlHL-19298-03 Pulmonary hemodynamics (dogs, cats)
** ROlHL-20143-02 Hypothermic circulatory arrest-Cerebral
vascular change (dogs)
ROlHL-20177-02 Effects of erythrocyte deformability on
tissue perfusion (rats)
** ROlHL-22149-01 Morphologic examination of brain
parenchymal vessels (cats)
CEREBROVASCULAR DISORDERS, CEREBRAL
ANEURYSM
R01HL-22573-01 Treatment of post surgical
vasoconstriction (dogs, monkeys, human, rats)
CEREBROVASCULAR DISORDERS, CEREBRAL
HEMORRHAGE
SEE ALSO CEREBROVASCULAR DISORDERS, MENINGEAL
HEMORRHAGES
** ROlHL-22149-01 Morphologic examination of brain
parenchymal vessels (cats)
R01HL-22573-01 Treatment of post surgical
vasoconstriction (dogs, monkeys, human, rats)
CEREBROVASCULAR DISORDERS, CEREBRAL
OCCLUSIONS AND THROMBOSIS
POlHL-06285-18 0164 Cardiovascular-respiratory
physiology and biochemistry - CPK MB isoenzyme
concentration to quantify infarct size (human, animals)
P50HL-17669-04 0001 Ischemic heart disease center
(SCOR) - Radioimmunoassays for CPK isoenzyme and
myoglobin (human, dog)
R01HL19038-02 Plethysmographic evaluation of carotid
blood flow (human, rabbits, dogs)
ROlHL-20898-02 Ultrasonic evaluation in direct arterial
surgery (models, cattle, human)
(contd)
tttluda routine melhodok>gy OR covers only general projects which preclude indexing at the specific level.
**Oriented signHicairtly to above subfect.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number
CiR
143
CER
ROIHL 22S73 01 liKlnmnl ot po\l suigicil
vtsKonstrlction (do|>l monktys. human. i«tsl
ftOlHL 23603 01 Moiplioianttis ot hypadensiva vascular
disaasa (ralsl
CEREBROVASCULAR DISORDERS,
CEREBROARTERIAL OCCLUSIONS
EXTRACRANIAL
ROIHL 169^^ Ob Caidiovasculai palholoiy (tats, rabbits)
** ROIHL 19038 0? Plethysmo|raphic avaluatioii ol carotid
blood tlow (human, rabbits, dois)
ROIHL 20381 03 Long t«rm study ot diabolic vascular
disaasa (human)
ROIHL 20898 02 Ultrasonic evaluation in direct arterial
surgery (models, cattle, human)
CEREBROVASCULAR DISORDERS, MENINGEAL
HEMORRHAGES
ROIHI :;W3 01 Treatment of post surgical
vasoconstriction (dogs, monkeys, human, rats)
CEREBROVASCULAR DISORDERS, STROKE
SEE ALSO CEREBROVASCUUR DISORDERS. CEREBRAL
HEMORRHAGE
SEE ALSO CEREBROVASCUUR DISORDERS. CEREBRAL
OCCLUSIONS AND THROMBOSIS
SEE ALSO CEREBROVASCUUR DISORDERS.
CEREBROARTERIAL OCCLUSIONS EXTRACRANIAL
SEE ALSO CEREBROVASCUUR DISORDERS. MENINGEAL
HEMORRHAGES
ROIHL'03341 22 Epidemiology of atherosclerosis in Evans
Co Georgia
ROIHL'04697'1. International heart disease epidemiology
(human)
POIHL'06285'18 0147 Cardiovascularrespiratoiy
physiology and biochemistry Metabolic regulation of
cerebral microcirculation (cats)
** P01HL07293-17 0054 Noninvasive cardiovascular
measurements - Detection of arterial occlusive disease
(human)
POlHL-07293-17 0058 Non-invasive cardiovascular
measurements - Peripheral duplex scanner physiologic
evaluation
** POlHL-1385116 Cyclotron produced isotopes in biology
and medicine (human, animals)
P50HL-14230-07 0088 A/S SCOR-Lipids. atherosclerosis
and thrombosis ■ Coronary risk factors in school children-
The Muscatine study
P50HL14230-07 0097 A/S SCOR-Lipids. atherosclerosis
and thrombosis - Studies of circulating platelet aggregates
(human)
** R01HL1580806 Role of angiotensinogen in hypertension
and stroke (human, rabliits)
** ROlHL-17754-03 Pathogenesis and prevention of
hypertension sequelae (rats)
ROlHL-19341-03 Ultrasonic detection of the atherosclerotic
plaque
R01HL19839-09 Factors in youth predisposing to chronic
diseases (former college students)
ROlHL-2078702 Thromboxanes and prostaglandins-
Biochemical pharmacology (rabbits, human)
ROlHL'20898-02 Ultrasonic evaluation in direct arterial
surgery (models, cattle, human)
** ROlHL-21088-02 Genetic patterns in deaths from Ml and
stroke in Utah
** ROlHL-21239-02 Isolation and mechanism of action of
thromboxane A2 (human, rabbits)
ROlHL-21843-01 Ischemia, diabetes and the
microcirculation (rats, cats, hamsters)
ROIHL'222 19-01 Prostacyclin and peroxides in blood and
membrane disease
N01HV-e2955-04 Data collection in clinical pathology and
morbid anatomy (men)
N01HV-72984-03 High blood pressure control program
(human)
NOlHV-72986-02
(human)
NOlHV-72987-02
(human)
NOlHV-72989-02
(human)
NOlHV-72990-00
(human)
High blood pressure control program
High blood pressure control program
High blood pressure control program
High blood pressure control program
CEREBROVASCULAR DISORDERS, TEMPORAL
ARTERITIS
SEE ALSO EYE CIRCUUTORY DISORDERS
R01HL09913-13 Cerebral veins-Anatomic and radiologic
correlation (human)
CEREBROVASCULAR DISORDERS DIAGNOSIS
(INCL EXAMS)*
SEE ALSO CEREBROVASCUUR VISUALIZATION'
POlHL-07293-17 0054 Non-invasive cardiovascular
measurements - Detection of arterial occlusive disease
(human)
ROlHL-09913-13 Cerebral veins-Anatomic and radiologic
correlation (human)
** POlHL-13851-16 Cyclotron produced isotopes in biology
and medicine (human, animals)
R01HL-19053-03 Vascular anatomy of the telencephalon
(human)
Tolerance to respiratory gases in
Glucose transport across choroid
ROIHI IS.I4I 03 Ullraionu ilnlndinii ul lh> •Ihriini InrutK
lilmiur
CEREBROVASCULAR EXAMINATIONS
SEE CERFBROVASCULAR DISORDERS DIAGNOSIS (INCL
EXAMS)*
CEREBROVASCULAR SURGERY
S(f Also NEUROSURGFRY
** ROIHL 22573 01 Treatment ot post surgical
vasoconstriction (dogs, monkeys, human, rats)
CEREBROVASCULAR SYSTEM
SEE ALSO EYE CIRCULATION
POIHL 08899 14 0008 Tolerance to respiratory gases in
heaHh and disease Hypoxia in regards to respiratory and
brain circulatory control (goats)
*• P01HL08899 14 0013 Tolerance to respiratory gases in
health and disease Oxygen and carbon dioxide effects
upon human brain metabolism
POIHL 08899 14 0019 Tolerance to respiratory gases In
health and disease High oxygen pressure upon carotid
chemoreceptor (cats)
** P01H10889914 0040 Tolerance to respiratory gases in
health and disease Metabolic gas influence on brain
vascular tissue (animals)
ROIHL 1664302 Fluorocarbon emulsions as artificial
blood (animals)
ROIHL 18657 03 Pharmacologic studies on neurogenic
digitalis effects (human, cats, dogs)
** ROIHL 22106-02 Diabetic cerebral vascular structure and
function
CEREBROVASCULAR SYSTEM, BLOOD-BRAIN
BARRIER
ROlHL'00487-29 Vasomotor tone and venous return
(human, dogs, monkeys )
** P01HL08899-14 0026 Tolerance to respiratory gases in
health and disease - Effects of oxygen on central nervous
system functions (rats, rabbits)
P01HL08899-14 0043 Tolerance to respiratory gases in
health and disease - Oxygen effects upon CNS and sensory
functions (human)
POlHL-08899-14 0054
health and disease
plexus (dogs)
POlHL-13851-16 Cyclotron produced isotopes in biology
and medicine (human, animals)
POlHL-14388-07 0180 Regulation of the circulation in
pathological states - Regulation of cerebral blood flow
(dogs, monkeys)
ROlHL-1580806 Role of angiotensinogen in hypertension
and stroke (human, rabbits)
ROlHL-18351-03 Brain metabolism, acid-base balance,
and respiration
ROlHL-2179901 Circumventricular sites of pressor action
of angiotensin II (rats)
ROlHL-21851-01 Cerebral microcirculation in experimental
hypertension (cats, rabbits)
ROlHL-226 17-01 Angiotensin, hypertension and the CNS
(sheep)
CEREBROVASCULAR SYSTEM, BLOOD-
CEREBROSPINAL FLUID BARRIER
POlHL-1034213 0019 The integrated function of
respiration and circulation - Cerebral circulation and
metabolism (dogs)
** POlHL-10342-13 0023 The integrated function of
respiration and circulation - Carbon dioxide transport and
CSF acid base balance (hogs, pigs)
POIHL- 197 3 7-02 0005 Cellular and molecular aspects of
respiratory physiology ■ Interaction of respiratory exchanges
and blood gas parameters (human, animals)
CEREBROVASCULAR SYSTEM, BRAIN
CIRCULATION
SEE ALSO CEREBROVASCUUR SYSTEM, CEREBRAL
CIRCUUTION
SEE ALSO EYE CIRCUUTION
NOlHI-02216-10 To develop biological flow NMR concept
(human, mammals non human)
ROlHL-00487-29 Vasomotor tone and venous return
(human, dogs, monkeys )
** POlHL-06285-18 0147 Cardiovascular-respiratory
physiology and biochemistry - Metabolic regulation of
cerebral microcirculation (cats)
** ROlHL-06736-18 Biogenic-mechanical factors in
microcirculation (rats, gerbils)
** P01HL-07896-15 0054 Environmental biomedical research
program - Myocardial effects of hemorrhagic shock (dogs)
** POlHL-07896-15 0055 Environmental biomedical research
program - Cerebral blood flow by Xenon'133 inhalation
(human)
" POlHL-08899-14 0012 Tolerance to respiratory gases in
health and disease - High oxygen for normal brain
metabolism and circulation in man
POlHL-08899-14 0024 Tolerance to respiratory gases in
health and disease - Effects of oxygen pressures on
physiological control systems (human, dogs)
POlHL-0889914 0034 Tolerance to respiratory gases in
health and disease - Hyperoxygenation and respiratory
response to acid-base stimuli (human, dog)
** POIMI IIHH'I'i 14 nil IK h.lrianct lo ittpililory la-.*-, in
ii, '.uli chtnge in alvtolai
.>r monkcytl
** POIlii ijnn 11 I'i iiiM I iiiicKnct lo ((tpiialocy laui in
health and ditaaM Dou reiponu ttuditi ot oiygan on
C02 reactivity in brain veiialt (human)
POIHl 08899 14 0041 Tolerance lo reipiratory |a<«t in
health and disna%r Blood gas transport and brtin
circulatory control (human)
*• POIHL 10342 13 0019 The integrated function ol
respiration and circulation Cerebral circulation and
metabolism (dogs)
ROIHL 10384 13 Blood flow and nucleotide metaboll^m
(animals)
POIHL 13851 16 Cyclotron produced isotopes in biology
and medicine (human, animals)
POIHL 14388 07 0193 Regulation of the circulation in
pathological states Ontogenesis ot central nervous system
amines in hyperlensinn (r.it- '
ROIHL 1452907 li-rorefie> "'oRs)
ROIHL 15659 05 Dynamic isolation studies of control of
respiration (human)
ROIHL 16022 05 Determinants of the ventilatory response
to hypoxia (goats, cats)
** ROIHL 1606605 Studies on neurogenic control of the
circulation (human, dogs)
** R01HL16643 02 Fluorocarbon emulsions as artificial
blood (animals)
ROIHL 17754 03 Pathogenesis and prevention of
hypertension sequelae (rats)
** ROIHL 18932 03 Brain microcirculation observed in vivo
after trauma (mice)
** P01HL18974-03 0001 Experimental neurogenic
hypertension program Central neural systems regulating
arterial pressure (rabbits)
POlHL-19737-02 0007 Cellular and molecular aspects of
respiratory physiology Average oxygen tension of tissue
using radioisotopes (dogs)
** ROIHL 20177 02 Effects of erythrocyte deformabilrty on
tissue perfusion (rats)
ROlHL'20399-03 Vascular control in experimental diabetes
mellitus (dog)
** ROIHL 2057202 0003 Hemodynamic relations to
metabolism in hypertension - Cardiac output and organ
blood flow in hypertension (rats)
R13HL-20765-01 Eleventh Princeton Conference on
Cerebrovascular Disease (new Jersey)
** ROlHL-21851-01 Cerebral microcirculation in experimental
hypertension (cats, rabbits)
" ROlHL-22149-01 Morphologic examination of brain
parenchymal vessels (cats)
ROlHL-23603-01 Morphogenesis of hypertensive vascular
disease (rats)
CEREBROVASCULAR SYSTEM, CAROTID
ARTERIES
ROlHL-01803-23 0015 Arteriosclerosis, glomerulonephritis.
rheumatic fever - Immunologic endothelial injury and lipid
diet atherosclerosis (rabbits, monkey)
POlHL-0729317 0058 Non-invasive cardiovascular
measurements - Peripheral duplex scanner physiologic
evaluation
POlHL-08682-15 0005 Regulation of the cardiovascular
system - Smooth muscle and mechanical properties of
blood vessels (dogs, human)
** POlHL-14388-07 0155 Regulation of the circulation in
pathological states - Cardiopulmonary afferent activity,
carotid chemo-baroreceptor reflexes
POlHL-14388-07 0180 Regulation of the circulation In
pathological states - Regulation of cerebral blood flow
(dogs, monkeys)
POlHL-1438807 0183
pathological states
regulation (dogs, rats)
POlHL-14388-07 0185
pathological states
rabbits, dogs)
POlHL-14388-07 0204
pathological states
Regulation of the circulation in
Vasopressin in cardiovascular
Regulation of the circulation in
Reflex control of venous tone (human.
Regulation of the circulation in
Reflex control of vascular resistance
in spontaneously hypertensive rats
P01HL14388-07 0208 Regulation of the circulation in
pathological states - Baroreceptor reflex function in normal
and hypertensive man
P01HL14388-07 0229 Regulation of the circulation in
pathological states - Mechanism of postural hypotension
(human)
ROlHL'16003-08 Sources and roles of calcium in smooth
muscle excitation (rats)
ROlHL-16952-05 Cardiovascular pathology (rats, rabbits)
P50HL-17655-04 0003 Study of ischemic heart disease -
Cardiopulmonary resuscitation (human, dog)
ROlHL-19038-02 Plethysmographic evaluation of carotid
blood flow (human, rabbits, dogs)
ROlHL-20 196-02 Regulation of coronary arterial smooth
muscle
ROlHL-20898-02 Ultrasonic evaluation in direct arterial
surgery (models, cattle, human)
ROlHL-21859-01
(human)
ROlHL-23603-01
disease (rats)
NOlHV-42961-06
with blood (dogs)
Unsteady flow in arterial bifurcations
Morphogenesis of hypertensive vascular
Evaluation of biomaterials in contact
(contd)
*£xdudes routine methodok)gy OR covers only general projects which preclude indexing at the specific level.
"Oiiefited significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
CER
NOlHV-72928-04 Develop high resolution ultrasonic
imaging techniques
NOlHV-72930-02 Atherosclerosis assessment-Angiography
and ultrasound (dogs, human)
CEREBROVASCULAR SYSTEM, CAROTID SINUS
ROlHL-05883-18 0004 Reflex control of resistance and
capacitance vessels - Left ventricular receptors with
nonmedullated vagal afferents (cats)
ROlHL-06143-18 Response of the totally denervated heart
to exercise (dogs)
POlHL-08682-15 0038 Regulation of the cardiovascular
system - Control of pulmonary circulation (dogs)
P01HL08805-15 0046 Regulation of ventilation and
pulmonary circulation - Sites and modes of interaction of
peripheral and central chemoreceptors
ROlHL-10951-11 Neural control of the heart (dogs, rats)
ROlHL-12415-10 Evaluation of left ventricular function
(dogs, rabbits)
ROlHL-1299009 Control of antidiuretic hormone secretion
and metabolism (dogs, rats, rabbits)
POlHL-13108-09 0021 Clinical heart transplantation
Autonomic reflex regulation of ventricular function (human)
P01HL13737-07 0009 Assisted circulation ■ Analytical
models
POlHL-1438807 0185
pathological states
rabbits, dogs)
POlHL-14388-07 0208
pathological states
and hypertensive man
POlHL-1438807 0209 Regulation of the circulation in
pathological states - Neural regulation of vascular
resistance in human hypertension
ROlHL-14529-07 Systems analysis of baroreflex (dogs)
ROlHL-15758-06 Catecholamine release in the heart
(dogs)
R01HL-I664816
activity (cats)
P01HL1691005 0002 Regulation of the peripheral
circulation - Coronary circulation (dogs)
PCIHL 16910-05 0005 Regulation of the peripheral
circulation - Control of circulation by baroreceptor and
chemoreceptor reflexes (dog. monkey)
ROlHL-17954-03 Narcotics and the circulation (human,
dogs, pigs, monkeys)
ROlHL-19039-03 Circulation studies by one vs two circuit
model (dogs)
ROlHL-19256-03
control (dogs)
R01HL19467-03
ROlHL-1967703
ROlHL-21071-02
Regulation of the circulation in
Reflex control of venous tone (human.
Regulation of the circulation in
Baroreceptor reflex function in normal
Integrated control of cardiovascular
Arterial baroreceptors in cardiovascular
Regulation of blood pressure (rats, dogs)
Venous structure and function (dogs)
Mechanisms of hypertension in
coarctation of the aorta (dog)
ROlHL-22546-02 Baroreceptor reflex mechanisms in man
** ROlHL-22667-01 Mechanisms of baroreceptor adaptation
in hypertension (dogs)
ROlHL-22715-01 Neural integration of the cardiovascular
reflexes (dogs))
CEREBROVASCULAR SYSTEM, CEREBRAL
ARTERIES
ROlHL-0991313 Cerebral veins-Anatomic and radiologic
correlation (human)
** ROlHL-1 5805-06 Cerebral arterial tone and reactivity
(rabbits)
R01HL19038-02 Plethysmographic evaluation of carotid
blood flow (human, rabbits, dogs)
R01HL19053-03 Vascular anatomy of the telencephalon
(human)
ROlHL-20787-02 Thromboxanes and prostaglandins-
Biochemical pharmacology (rabbits, human)
ROlHL-22573-01 Treatment of post surgical
vasoconstriction (dogs, monkeys, human, rats)
CEREBROVASCULAR SYSTEM, CEREBRAL
CIRCULATION
** POlHL-06285-18 0147 Cardiovascularrespiratorv
physiology and biochemistry - Metabolic regulation of
cerebral microcirculation (cats)
ROlHL-09913-13 Cerebral veins -Anatomic and radiologic
correlation (human)
** R01HL1277508 Cerebral microcirculation (mice)
** P50HL-14230-07 0099 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Morphological, cytochemical study of
normal and altered vasculature (mice)
POlHL-1438807 0180 Regulation of the circulation in
pathological states - Regulation of cerebral blood flow
(dogs, monkeys)
Cerebral arterial tone and reactivity
ROlHL-15805-06
(rabbits)
ROlHL-18590-03
(dogs, monkeys)
R01HL1905303
(human)
P50HL-19190-02 0006
management of IRDS
P50HL-191 90-02 0007
management of IRDS
rat)
ROIHL 2014302 Hypothermic circulatory arrest-Cerebral
vascular change (dogs)
Cerebral blood flow after cardiac arrest
Vascular anatomy of the telencephalon
Pulmonary SCOR-Pathophysiology,
Asphyxia -Respiratory control (dogs)
Pulmonary SCOR-Pathophysiology,
Asphyxia-Cerebral metabolism (dog,
144
** POlHL-20581-01 0003 Vascular neuroeffector
mechanisms in health and disease - Cerebrovascular
neuroeffector characteristics (animals)
** ROlHL-2076102 Study of cerebral blood flow with stable
xenon and computerized tomography
ROlHL-2261701 Angiotensin, hypertension and the CNS
(sheep)
CEREBROVASCULAR SYSTEM, VENOUS SINUSES
INTRACRANIAL
R01HL0991313 Cerebral veins -Anatomic and radiologic
correlation (human)
CEREBROVASCULAR VISUALIZATION*
** ROlHL'19053-03 Vascular anatomy of the telencephalon
(human)
CEREBROVASCULAR VISUALIZATION,
CEREBRO ANGIOGRAPHY*
" ROlHL-09913-13 Cerebral veins-Anatomic and radiologic
correlation (human)
CEREBRUM
SEE BRAIN, CEREBRUM
CEROID
SEE LIPOFUSCIN-CEROID
CERUBIDINE
SEE ANTIBIOTICS, DAUNOMYCIN
CERULOPLASMIN
SEE METALLOPROTEINS, CERULOPUSMIN
CESIUM
SEE METALS, ALKALI METALS, CESIUM
CESTODE ANTIGENS
SEE IMMUNOLOGY, ANTIGENS HELMINTHIC
CFM MODEL
SEE BIOLOGICAL TRANSPORT, MEMBRANE MODELS
CHAIN LENGTH (CHEMISTRY)
SEE CHEMICAL STRUCTURE, CHAIN LENGTH
CHALONES
SEE CELL GROWTH REGUUTION, CHALONES
CHEDIAK-HIGASHI SYNDROME
SEE METABOLIC DISORDERS INBORN, CHEDIAK-HIGASHI
SYNDROME
CHELATES, METAL
SEE METAL COMPLEXES
CHELATING AGENTS
SEE METAL COMPLEXES, LIGANOS, CHEUTING AGENTS
CHELATION
SEE METAL COMPLEXES, LIGANDS. CHEUTING AGENTS
CHELATION THERAPY
SEE IRON CHELATION THERAPY
CHEMICAL AGGREGATES
SEE ALSO MOLECULAR CONDENSATIONS
ROlHL-0745116 Hemoglobin S gelation and hemoglobin
allostery (human)
** P60HL16005-05 0015 Comprehensive sickle cell center -
Molecular basis for the sickling phenomenon
ROlHL-16601-05 Structure and function of blood proteins
(human, cattle)
P60HL17265-04 0002 Community blood resource center
support • Research-Human factor VIII
ROlHL-18625-03 Organization of arterial ground substance
(cattle)
ROlHL-20350-02 Crystal structure of lipids-Cholesterol
P01HL-21016-02 0002 Sickle cell anemia and other
hemoglobinopathies ■ Molecular events proceeding gelation
of Hb S
ROlHL-21626-01 Proteoglycans of animal lung
parenchyma (cattle, pigs, rabbits)
ROlHL-21649-01 Biochemistry of lung proteoglycans
(mammals)
** ROlHL-22654-01 Molecular structure of sickle cell fibers
(human)
ROlHL-22682-01 Structure and function of high density
lipoprotein (human, rat)
CHEMICAL AGGREGATES, MICELLE FORMATION
SEE ALSO PHYSICAL PROPERTIES, COLLOIDS, COLLOIDAL
STATE
SEE ALSO PHYSICAL PROPERTIES, SOLUTIONS ASSOCIATION
P01HL082 14-15 0041 Chemical and biological properties
of lipids - Physico-chemical regulation of enzymes in lipid
metabolism
ROlHL-12528-10 NMR relaxation of liquid crystal systems
R01HL18623-12 Physical chemistry of biologically active
lipids (bacteria, plant, cattle, human)
RGIHL-18636-02 Fatty acids and cholesterol transport
(rats)
ROlHL-22570-01 Interactions of sterols in biological
systems (human)
CHEMICAL AND DRUG INFORMATION SYSTEMS
R01HL07878-16 Metabolism of neutral sterols (rats,
rabbits)
Pathophysiology of edema (rats, cats)
Surface thrombogenesis -Mechanisms and
CHE
CHEMICAL AND DRUG REGISTRIES, REFERRAL
CENTERS AND RESOURCES
ROlHL-10582-12 Thrombosis and hemostasis -Analysis,
methods and standards (human, cattle, venom)
ROlHL-17726-03 Bacterial heparinase in diagnostic
coagulation studies
POlHL-17813-04 0008 Lung disease and the oxygenation
of blood and tissue - Pulmonary regulation of systemic
blood pressure (human, rabbits, rats)
CHEMICAL ASSOCIATED CARCINOGENS
SEE NEOPLASTIC TRANSFORMATION. CARCINOGENESIS,
CHEMICAL
CHEMICAL BOND FREQUENCIES
SEE CHEMICAL BONOS, VIBRATIONS
CHEMICAL BONDS
SEE ALSO CARBOHYDRATES, PROTEIN BOUND
CARBOHYDRATES
SEE ALSO CHEMICAL REACTION SITES
SEE ALSO CHEMICAL STRUCTURE, STEREOCHEMISTRY,
CONFORMATIONS
SEE ALSO DRUGS RECEPTORS
SEE ALSO ELECTRONIC SPECTRA, MOLECULAR ORBITALS
SEE ALSO GLOBULINS, CORTICOSTEROID BINDING GLOBULIN
SEE ALSO HALOPROTEINS, PROTEIN BOUND IODINE
SEE ALSO MOLECUUR INTERACTIONS NONBONDING
ROlHL-13157-09 Molecular oxygen carriers-Synthesis,
structure, bonding
ROlHL-15640-06 Thermodynamic studies on model oxygen
carriers
ROlHL-1608705 Structural and dynamic study of model
heme complexes (yeast)
ROlHL-18746-02 Chemical studies on proteolipid
apoproteins (cattle)
ROlHL-18764-03 Biosorbable thromboresistant surfaces
(dogs, rats, swine, human)
ROlHL-21 194-02 Development of antithrombogenic plastic
biomaterials
ROlHL-21498-02
M POlHL-22163-01
prevention
** POlHL-22163-01 9001 Surface thrombogenesis-
Mechanisms and prevention - Polymers for studing blood-
material interactions core
CHEMICAL BONDS, BINDING
SEE ALSO MOLECUUR CONDENSATIONS
SEE ALSO PROTEIN BINDING
R01HL01974-24 Ion-pump in the erythrocyte (rabbits,
guinea pigs)
POlHL-03174-23 0009 Mechanisms of acute vascular
reaction to injury - Mast cell lipid interaction (human, rats)
POlHL-03174-23 0011 Mechanisms of acute vascular
reaction to injury ■ Mutagen metabolism by artery wall in
etiology of atherosclerosis (human, animals)
ROlHL-05360-19 Cholesterol biosynthesis and its control
in liver (rats)
R01HL05791-18 Structure and function in hemoglobins
(human)
P01HL-0e285-18 0207 Cardiovascular-respiratory
physiology and biochemistry - Feedback control of
cholesterol synthesis in non-hepatic tissues (animals)
POlHL-06308-18 0025 Mechanisms and therapy of
circulatory disease - Subcellular calcium pools in the
genesis of arrhythmias (dogs)
P01HL06314-17 0055 Immunologic mechanisms in
cardiovascular disease - Genetics and cell biology
POlHL-06664-17 0039 Cardiopulmonary function in
remediable vascular disease - Transepithelial active
transport and cell volume regulation (frogs)
P01HL06835-17 0033 Cardiovascular disease - Structure-
activity relationship of angiotensin II analogs (rats)
POlHL-09011-15 0013 A research and resource program
in blood - A quantitative study of immunological
enhancement (mice)
ROlHL-10503-13 Cardiac ion transport and ultrastructure
(rats, guinea pigs, rabbits)
POIHL'1131012 0096 Mechanisms of cardiovascular
disease - Complement chemistry and biology (human.
rabbits)
ROlHL-12997-07 Myocardial defects induced by potassium
depletion (human, rats, cats)
R01HL13581-11 Reactions of oxygen with heme proteins
R01HL-13870-09 Control of myocardial sarcotubular
calcium stores (dogs)
P50HL-14147-08 0014 Specialized center of research in
thrombosis - Theoretical models for electrostatic effects In
blood clot formation
R01HL14775-08 Mechanisms of drug action in vascular
smooth muscle (dog, rabbits)
R01HL14990-07 Lipid transport in avian species
(chickens)
P50HL-15061-07 0009 Response of lung to injury ■
Alveolar macrophages (human, rabbits)
POlHL-15194-07 0006 Pathophysiology of
cardiopulmonary dysfunction ■ Kinetics of gas exchange-
Velocity of Bohr effect in erythrocytes (human)
R01HL15698-12 Factors affecting the action of
anticoagulants (rats, human)
(contd)
'Excludes routine methodotogy OR covers only general projects which preclude indexing at the specific level.
**Onented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number
CHi
POIHl 1S83S06 0018 Study ol muscigs tulattd lo hemt
dis<a» Phatniicoloiy ot e>cita|{on itiupllng in I1lll^rl<'
(liD|. baintclts)
ROIML 16037 06 Molaculat piopailias ol cardiac
adi«nai(ic lacaptois
ROIHL I60S2 0S Cardiac ilycosides Mechanism ot
Inotropic action (dogs)
ROIHl I60!)9 06 Strurluia and function ol saium
lipoproteins (cattle, human)
ROIHL 16101 Ob Piotein lipid inlciaction (baclerii,
models)
Ion movements and membianos in
Fast kinetic study ol calcium
POIHI 16117 OS 0003
cardiovascular control
membrane interactions
POIHI 16117 05 0005
cardiovascular control
Ion movements and membranes in
Properties ol isolated cell
membranes (rabbits, cats)
POIHL 16251 06 0002 Membrane bound enzymes in heart
and other tissues Structural basis ol regulation ol
cardiac succinate dehydrogenase
ROIHL 16355 05 Reactions ol thrombin and collagen with
platelets (human)
POIHI'16411 04 0002 Blood systems in coagulation and
vessel disease Early stages of coagulation and
cardiovascular disease (human, rabbits)
POIHL 16411 04 0005 Blood systems in coagulation and
vessel disease Chemical analysis of serum components
associated with coagulation (human, animal)
ROIHL'16474'05 Antibiotic ion interactions (model
membranes)
ROIHL 1663413 Regulation of metabolism in tibroblasts
and platelets (human, rabbits, sheep)
ROIHL 1667405 Airborne metals and lung permeability
(builtrogs. rats)
POlHL-16683-04 0001 Function and growth of cardiac
and skeletal muscle - Light chains of the skeletal and
cardiac myosin molecule (rabbits, frogs)
POlHL-16683-04 0006 Function and growth of cardiac
and skeletal muscle - Chemical studies of the contractile
system-Development of new reagents
ROIHL-1671003 Myocardial subcellular localization of
calcium (dogs)
P01HL16833-04 0003 Hemoglobin and red cell system in
hemoglobinopathies - Oxygen binding curves and equilibria
(human)
POlHL-1743005 0005 Control of coagulation • The
activation of prothrombin (human, cattle, dogs)
R01HL1784404 Artificial blood substitutes-02-binding
iron chelates (human, mammals)
POlHL-18208-04 0007 Center for the study of blood cell
rheology - RBC membrane protein (human)
POlHL-18576-03 0003 Thrombosis research program
project - Biocompatible materials
P01HL18577-03 0001 Lipoprotcins-Ccll surface
interactions ■ Structural studies of serum lipoproteins in
man and dogs
POlHL-18577-03 0003 Lipoproteins-Cell surface
interactions - Mechanism of lipid exchange in lipoproteins
and cell membranes
POlHL-18577-03 0005 Lipoproteins-Cell surface
interactions - Chemical synthesis of apolipoproteins and
apoliprotein fragments
ROlHL-1873703 Human erythrocyte membrane structure
R01HL18893-03 Mechanism of angiotensin action -Role of
receptor (rats)
ROlHL-19027-03 Calcium and cyclic AMP in causation of
hypertension (rats)
P01HL19259-03 0001 Digoxin-specific antibody in human
therapy - Primary structure of monoclonal antibodies
(rabbits)
POlHL-19259-03 0004 Digoxin-specific antibody in human
therapy • Digitalis-specific antibodies pharmacological
studies (human, dogs, sheep)
ROlHL-19282-03 Regulation of the activation of human
factor X
ROlHL-19423-03
rats)
R01HL19676-02
pulmonary surfactant
POlHL-19737-02 0004 Cellular and molecular aspects of
respiratory physiology - Rapid reactions and erythrocyte
exchanges of blood during respiratory transport
ROlHL-20079-02 0001 Thromboresistant material - Active
and passive thromboresistant surfaces
ROlHL-20087-02 Developmental processes in pulmonary
hypertension (rats)
ROlHL-20116-01 Heart lactate dehydrogenase-The complex
with NADH (pig)
ROlHL-20161-02 Role of gamma-carboxyglutamic acid in
blood coagulation (human, cattle)
ROlHL-2047103 Atherosclerosis and diabetes mellitus
(human)
ROlHL-2097110 Membrane glycoproteins of platelets and
leukocytes (human)
POlHL-20994-02 0009 Dynamics of neutrophil elastase in
the lung • Biosynthesis and degradation of elastin in
emphysema (human, hamsters)
ROlHL-21030-01 Calcium regulation and hypertension
(rats)
ROlHL-2111202
secretion in man
ROlHL-21273-02
Catecholamine action on the heart (cats.
Physico-chemical interactions in
145
ROIHI 21329 02 beta reioploi regulation and cardiac
sl^^■^ uf drug action (cat. guinea pig. rat)
KOIHI ^1342 02 Isolation and analysli ol sodium channel
from hi'art (Irogs)
ROIHI 21493 02 Contractility in cardiac lillure (hamsltrs)
ROIHl 21820 01 Regulaloiy role ot myosin in cardiac
hypertrophy (dogs)
ROIHL 21975 01 Studies on normal and abnormal factor
IX (human, dogs, cows)
R23HL 2201 101 Adrenergic receptor cyclase system in
sensiti/ed lung (rats, guinea pigs)
ROIHL 2207' 01 Vasoactive amine disposition in rulturcd
endothelium (rabbits)
ROIHL 22136 02 Histamine and cardiac adenyl cyclase
ROIHL 22402 01 Heparin biophysical, chemical and
biological aspects (mice, human)
R23HL 22490 01 Neurotransmitter receptors ot cultured
heart cells
ROIHL 22570 01 Interactions of sterols in biological
systems (human)
R23HL 22575 01 Factors modifying cardiac digoxin effects
and content (dogs, cats)
POIHL 2261901 0003 Cellular mechanisms of heart
failure Digitalis induced inotropy in myocardial ischemia
heart failure (animals)
POIHL 2261901 0004 Cellular mechanisms of heart
failure - Mechanism of action of Na. KATPase (sheep,
cattle)
POIHL 22619 01 0005 Cellular mechanisms of heart
failure Molecular mechanism of regulation of cardiac
muscle contraction (cattle)
POlHL-226 19-01 0006 Cellular mechanisms of heart
failure Phosphorylation of contractile proteins in cardiac
muscle contraction (dogs, rabb
ROlHL-22671-01 Removal of senescent and stored human
red cells
ROlHL-2339201 Membrane binding and transport of
calcium and potassium ionophores
ROlHL-23626-01 A study of the regulation of myocardial
hypertrophy (rats)
NOlHV-12017 15 Fabrication of grafted hydrogel coatings
for plastic heart assist devices
CHEMICAL BONDS, BOND CLEAVAGE
POIHLI 13 10-12 0096 Mechanisms of cardiovascular
disease Complement chemistry and biology (human.
rabbits)
ROlHL-1 1963-10 Biochemistry of blood vessel formation
and disease (swine)
R01HL14680-07 Specific enrichment of myoglobins for
carbon 13 NMR (catacea)
Structure-function studies of human
Inhibitors of proteinases (human, cattle,
Primary structure of prothrombin (cattle.
Radioimmunoassay of angiotensinogen
Structure of factor Vlll-Von Willebrand
Aldosterone binding, clearance, and
Fibrinogen labeling with radiometals
ROlHL-15615-06
factor VIII/vWF
ROlHL-15892-05
swine)
ROlHL-161 50-05
human)
R01HL18561-03
(human)
ROlHL-21379-01
protein (human)
ROlHL-22505-01 Molecular pathology of fibrinogen and
factor XIII (human, animals)
ROlHL-22955-01 inetics of prothrombin activation
CHEMICAL BONDS, COVALENT
POlHL-13738-08 0005 Cardiac assist devices and
artificial hearts - Development of new materials for
artificial heart and assist devices (sheep, dog)
POlHL-15596-05 0020 Coagulation, fibrinolysis,
hemostasis and hepatitis - Affinity chromatography
P01HL16251-06 0001 Membrane-bound enzymes in heart
and other tissues ■ Structure of covalently bound flavins
(bacteria, yeast, mammals)
ROlHL-22471-01 Biochemistry of prothrombin quick
(human)
CHEMICAL BONDS, CROSSLINKS
R01HL02063-23 Biochemistry and function of lipids and
cell membranes (human, yeast, animals)
ROlHL-022 12-23 Coagulation of blood (human)
ROlHL-05791-18 Structure and function in hemoglobins
(human)
POlHL-06285-18 0173 Cardiovascular-respiratory
physiology and biochemistry ■ Skeletal and cardiac muscle
function
POlHL-06350-17 0020 Hemostasis research program
project - Structure and function of coagulant venom
proteases
♦* POlHL-06835-17 0027 Cardiovascular disease - Studies
in thrombosis-cross-linking of fibrinogen (human)
ROlHL-07379-13 Structure and function of fibrinogen
(human)
POlHL-l 13 10-12 0106 Mechanisms of cardiovascular
disease - Biochemical characterization of the collagens in
vascular tissue (catte)
R01HL-U614-I1 Trace elements in nutrition (chickens,
rats, human)
ROlHL-1196310 Biochemistry of blood vessel formation
and disease (swine)
** ROlHL-12561-11 Cardiovascular studies on copper
deficiency (swine)
*Exdurtss routine methodokigy OR covers only general projects whicti preclude indexing at the specific level
••Qriefrted significantly to above subject.
CHI
POIHI n2fa2 0/ U012 Arterial wall in alhiroidaiotit
Characteri/ation of cunnrrtive tr.iur romponrtit'. 'animali)
POIHL 132(>2 07 0015 Arttrial will in atlieroulerotit
Croiihnkage biotynlhaili in aortic tlitlin and c«llattn
(inimalt)
P50HL 14217 08 0048 Specialized center of research in
IhromboMs Fibnnohfiis section Structural studies (human.
animal)
P50HI 14217 08 0049 Specialized lonler ol research in
IhroniboMs Fibrinolysis section Clinical ttudiet
P60HL 1515/0/ 0009 Comprehensive center lor ilckl*
call disease Red cell membrane alterations during
sickling (human)
P60HI 1515/ 0/ 0018 Comprehensive center lor sickle
cell disease Red blood cell membrane physiology in iickle
cell anemia (human)
POIHI 15195 04 0001 Program protect in biological
materials Design and synthesis
POIHL 1519504 0003 Program protect in biological
materials Mechanical evaluation and labrication
POIHL 1548606 0001 Studies on thrombosis Studies on
chemistry ol librinogen (human, dogs)
POIHL 15486 06 0002 Studies on thrombosis
Characterization ol antisera to fibrinopeptide B (human.
rabbits)
ROIHL 15793 06 Molecular aspects of erythrocyte
membrane resealing (human)
POIHL 15832-06 0001 Chemical structural predispositions
to lung injury Chemical composition ol lung connective
tissue proteins (human, animals)
P60HL 16005-05 0015 Comprehensive sickle ceil center
Molecular basis for the sickling phenomenon
POIHL 16118 06 0006 Study of emphysema Metabolism
of elastin (hamsters)
R01HL16150-05 Primary structure of prothrombin (cattle.
human)
ROlHL-16361-03 Fibrin complexes in intermediary
coagulation (human, rabbits)
POIHL 16607-05 0005 Calcium ion and control of
cardiovascular function Chemical modifications of the
sarcoplasmic reticulum membranes (rabbits)
ROlHL-17865 04 Studies on aging -Effects of sex
hormones (rats, dogs)
R01HL-17879-04 Molecular structure of the ouabain
sensitive ATPase (dogs)
ROIHL- 17909-04 Drug treatment of vascular scleroprotein
defects (human, turkeys)
P01HL1820804 0005 Center for the study of blood cell
rheology - RBC deformability and capillary flow
interrelations (human, mice)
ROlHL-18308-03 Comprehensive studies of mucociliary
transport (dogs)
POIHL 18576-03 0002 Thrombosis research program
project - Molecular basis of fibrin formation (human, cattle,
lamprey)
ROlHL-18593-03 Characterization of heart valve collagen
(human, pig)
ROlHL-18672-03 Dynamic studies ot clot structure
formation (human)
ROlHL-18918-03 Characterization of lung elastins (rat.
rabbit, chicken, Rhesus)
ROlHL-19429-03 Phagocytosis-lngestion in alveiolar
macrophages (rabbits)
P01HL19717-02 0001 Response of the lung to injury -
Lung elastic tissue (animals)
P01HL19717-02 0002 Response of the lung to injury
Prolyl hydroxylase, lysyl hydroxylase and lung collagen
biosynthesis (rabbits)
POlHL-19717-02 0008 Response of the lung to injury -
Experimental models of lung disease
P01HL19717-02 0023 Response of the lung to injury -
Postnatal lung development-Cells, connective tissue and
physiology (animals)
POlHL-1971702 0028 Response of the lung to injury -
Compensatory growth of the lung following pneumonectomy
(rabbits)
ROlHL-20074-02 Structure and function of amidinated
human hemoglobin
R01HL-20I06-02 Coupling of platelet contractile proteins
to fibrin (human)
R01HL-20319-02 Assembly, structure and interactions of
fibrin (human)
R01HL-20391-03 Polydisperse LDL-Structure, metabolism
and function (human)
R01HL-20500-02 Diabetic human brain microvascular
basement membrane (human)
POlHL-20592-02 0001 Cell biology of cardiac and
skeletal muscle - Molecular mechanism of muscle
contraction (animals)
ROlHL-2076402 Elastin and calcification in pulmonary
and vascular disease (human, mammals)
P60HL-20985-01 0006 Northern California sickle cell
center - Antisickling properties of imidoesters (human, rats)
POlHL-21016-02 0003 Sickle cell anemia and other
hemoglobinopathies - Role of non-S hemoglobin in gelation
and sickling
R23HL-21 129-02 The antisickling effects of imidoesters
R01HL-21139-02 Molecular biology of factor XIII (human)
ROlHL-2204001 Regulation of lysyl-cross-linking in
vascular tissue (rats, turkeys)
ROlHL-22208-02 Elastin structure, fibrogenesis and
disease (chickens, rabbits)
(contd)
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number
CHE
ROlHL-22239-01 The molecular basis of electrical
excitability (chick embryos, rats)
ROlHL-22505-01 Molecular pathology of fibrinogen and
factor XIII (human, animals)
ROlHL-22955-01 inetics of prothrombin activation
ROlHL-2324901 Actin-myosin interaction in pulmonary
smooth muscle (cattle)
ROlHL-2 36 15-01 Biochemistry of contractile proteins
(chicken, rabbit)
CHEMICAL BONDS, DISULFIDE BONDS
ROlHL-02751-21 Function and metabolism of serum
albumin (mammals, fish, amphibians)
** ROlHL-07379-13 Structure and function of fibrinogen
(human)
P50HL-14147-08 0018 Specialized center of research in
thrombosis ■ Biochemical aspects of platelet function in
thrombosis and cell growth (human)
R01HL15535-06 Structure and function of human plasmin
R01HL1615005 Primary structure of prothrombin (cattle,
human)
P60HL17265-04 0002 Community blood resource center
support - Research -Human factor VIII
CHEMICAL BONDS, HYDROGEN BOND
ROlHL-13909-27 Physiochemistry and immunology of
macromolecules
ROlHL-16087-05 Structural and dynamic study of model
heme complexes (yeast)
POlHL-16833-04 0003 Hemoglobin and red cell system in
hemoglobinopathies - Oxygen binding curves and equilibria
(human)
CHEMICAL BONDS, HYDROPHOBIC
POlHL-06285-18 0215 Cardiovascular-respiratory
physiology and biochemistry - Conformation of biopolymers
POlHL-15195-04 0001 Program project in biological
materials - Design and synthesis
POlHL-16748-05 0001 Cellular and immunological basis
of pulmonary diseases Mechanisms of alveolar
macrophage function and dysfunction (human, rabbits)
POlHL-18576-03 0003 Thrombosis research program
project - Biocompatible materials
ROlHL-19639-02 Permeability transients of carriers,
channels and heart
CHEMICAL BONDS, IONIC
PDlHL-06285-18 0200 Cardiovascular-respiratory
physiology and biochemistry - Medullary counter-current
system (animals)
CHEMICAL BONDS, UNSATURATED
COMPOUNDS, POLYENES
POlHL-08214-15 0030 Chemical and biological properties
of lipids - Fatty acid biosynthesis in plant cell cultures and
in plants
ROlHL-16660-06 Phospholipid-cholesterol and
phospholipid-protein interactions
ROlHL-21764-01 Ultramicroanalysis of prostaglandins and
related compounds (rats)
CHEMICAL BONDS, VIBRATIONS
SEE ALSO OPTICS, CHROMOPHORE*
ROlHL-05556-19 Proteins, lipoproteins-Structure and
reactivity (chicken, human, diving mammals)
ROlHL-16087-05 Structural and dynamic study of model
heme complexes (yeast)
ROlHL-22233-01 Characterization of bio-materials by
elastic property
CHEMICAL CARCINOGENS
SEE NEOPLASTIC TRANSFORMATION. CARCINOGENS,
CHEMICAL
CHEMICAL CONTAMINANTS-POLLUTANTS,
ENVIRONMENTAL (GENERAL)
SEE ENVIRONMENTAL HEALTH, CONTAMINATION (GENERAL)
CHEMICAL MODELS
SEE MODELS, CHEMICAL
CHEMICAL REACTION RATES
SEE ALSO CHEMISTRY, ANALYTICAL METHODS, TEMPERATURE
JUMP*
P01HL-06664-17 0040 Cardiopulmonary function in
remediable vascular disease - The coupling of ion transport
to metabolism (toads)
P50HL-14147-08 0013 Specialized center of research in
thrombosis - Mathematical models of blood coagulation
kinetics
POlHL-15194-07 0006 Pathophysiology of
cardiopulmonary dysfunction ■ Kinetics of gas exchange-
Velocity of Bohr effect in erythrocytes (human)
PO1HL15194-07 0009 Pathophysiology of
cardiopulmonary dysfunction - Kinetics of gas exchange -
Diffusion and erythrocytes reaction rates (human, dogs)
ROIHL- 15648-06 Lipid metabolism -Transport by lateral
diffusion (human, rabbit, cattle)
•• P01HL-I7731-04 0010 Physiological basis of pulmonary
disease - Gas exchange kinetics (dogs)
ROlHL-18764-03 Biosorbable thromboresistanf surfaces
(dogs, rats, swine, human)
ROIHL- 1 88 18-04 Stereochemical mechanism of sickling of
hemoglobin S (human)
146
ROlHL-19491-03 Mechanism of iron storage and
mobilization by ferritin (horse)
P60HL-20985-01 0003 Northern California sickle cell
center - Kinetics of sickling and clinical manifestations in
sickling disorders (human)
ROlHL-21513-02 Metabolism of trans fatty acids (human,
rats, swine)
ROlHL-22538-01 Myosin as a multi-enzyme complex (dogs,
rabbits)
ROlHL-23392-01 Membrane binding and transport of
calcium and potassium ionophores
CHEMICAL REACTION RATES, FAST REACTIONS
ROlHL-13035-08 Heart mitochondrial malate
dehydrogenase regulation
ROlHL-15284-06 Hemoglobin and myoglobin kinetic
studies (human, animals)
ROlHL-17963-04 Human erythrocyte carbonic anhydrase
ROlHL-18048-04 Dynamics of artificial and biological
membranes (human)
** ROlHL-19488-03 Picosecond laser studies of heme-
proteins
** POlHL-19737-02 0004 Cellular and molecular aspects of
respiratory physiology - Rapid reactions and erythrocyte
exchanges of blood during respiratory transport
CHEMICAL REACTION SITES
SEE ALSO DRUGS RECEPTORS
ROlHL-02751-21 Function and metabolism of serum
albumin (mammals, fish, amphibians)
POlHL-09011-15 0005 A research and resource program
in blood - Characterization of hepatitis-B antigen and the
cause of serum hepatitis (human)
ROlHL-12585-10 Structural properties of malate
dehydrogenase (swine)
ROlHL-12740-10 Hypocholesterolemic agents-
Stereochemistry (rats)
ROlHL-13160-08 Human thrombin (also cattle)
ROlHL-13581-11 Reactions of oxygen with heme proteins
** ROlHL-13652-08 Metal sites in metalloproteins
(mushroom)
P50HL-14217-08 0058 Specialized center of research in
thrombosis - Mechanisms of induction and inhibition of
platelet reaction (human, pig)
P50HL-142 17-08 0062 Specialized center of research in
thrombosis - Coagulation section-Factor VIII and Factor XII
(human, cattle)
ROlHL-14820-07 Factors affecting physiology of biological
membranes (human)
ROlHL-14865-07 Biochemical studies on the pathogenesis
of emphysema (human, rats)
P50HL-15061-07 0009 Response of lung to injury -
Alveolar macrophages (human, rabbits)
P50HL-15061-07 0012 Response of lung to injury -
Hyperbaric oxygen, carbon monoxide, and ozone or peroxide
toxicity (rats)
ROlHL-15293-07 Sickle cell hemoglobin-Interactions and
aggregation (human)
POlHL-15596-05 0007 Coagulation, fibrinolysis,
hemostasis and hepatitis - Structural studies and
fractionation of urokinase (human)
ROlHL-15892-05 Inhibitors of proteinases (human, cattle,
swine)
ROlHL-16087-05 Structural and dynamic study of model
heme complexes (yeast)
** POlHL-16251-06 0008 Membrane-bound enzymes in heart
and other tissues - Iron-sulfur centers and phospholipids
modulation of succinate dehydrogenase
ROlHL-16628-05 Regulation of lipid metabolism (rats)
ROlHL-16634-13 Regulation of metabolism in fibroblasts
and platelets (human, rabbits, sheep)
ROlHL-16860-05 Mossbauer studies of respiratory
hemoproteins
ROlHL-17559-03 Structural elucidation of heart
cytochrome-C oxidase
ROlHL-186 12-03 Thin filament control of heart contraction
(cattle)
ROlHL-188 19-07 Chemical studies on sickle cell
hemoglobin (human)
ROlHL-20391-03 Polydisperse LDL-Structure, metabolism
and function (human)
ROlHL-21096-02 Sickle cell crisis-Role of the erythrocyte
membrane (human)
ROlHL-21170-01 Molecular structure of human serum
transferrin
CHEMICAL REACTION SITES, ALLOSTERIC SITES
ROlHL-05791-18 Structure and function in hemoglobins
(human)
ROlHL-07451-16 Hemoglobin S gelation and hemoglobin
allostery (human)
ROlHL-12524-10 Reaction of hemoglobin with ligands and
antibodies (human, carp)
ROlHL-13035-08 Heart mitochondrial malate
dehydrogenase regulation
ROlHL-13164-07 Interaction of the alpha and beta chains
of human hemoglobin
ROlHL-13531-06 Coboglobins -Cobalt substituted myo- and
hemoglobins
ROlHL-14020-06 Characterization of myosin from blood
platelets (rabbit)
ROlHL-15460-06 Molecular adaptation-Hemoglobin
systems of fish (marine)
CHE
ROlHL-17976-18 Chemical agents and heart glycolytic
enzymes (sheep)
ROlHL-18304-03 FTinfrared spectroscopy of heart muscle
energetics (cattle)
ROlHL-21483-01 Electronic, thermodynamic and kinetics
of hemoglobin
ROlHL-22194-02 Allosteric function of platelet contractile
proteins (human)
ROlHL-22239-01 The molecular basis of electrical
excitability (chick embryos, rats)
ROlHL-22325-01 Thermodynamics in respiratory protein
binding (human, trout)
CHEMICAL REACTION SITES, FUNCTIONAL
GROUPS
SEE ALSO ALKYL (GROUPS)
ROlHL-05791-18 Structure and function in hemoglobins
(human)
ROlHL-05949-18 Biochemistry of muscle contraction (rats,
rabbits)
POlHL-0821415 0010 Chemical and biological properties
of lipids ■ Infrared spectroscopy of lipids
ROlHL-08299-16 Molecular biology of hemerythrin and
hemocyanin (invertebrates)
ROlHL-09544-12 Biochemistry of contractile proteins
(animals)
ROlHL-11511-10 Structure of ferritin and its role in iron
metabolism (horse, rats, human)
ROlHL-12524-10 Reaction of hemoglobin with ligands and
antibodies (human, carp)
R01HL-12526-09 Raman spectra of heme proteins and
related molecules
ROlHL-14508-10 Structure and function of respiratory
hemoproteins
R01HL14680-07 Specific enrichment of myoglobins for
carbon 13 NMR (catacea)
ROlHL-14938-06 Contractile proteins of heart muscle
(dogs, rabbits)
ROlHL-15155-05 Rheology of pulmonary secretions (dogs)
ROlHL-15460-06 Molecular adaptation-Hemoglobin
systems of fish (marine)
ROlHL-15535-06 Structure and function of human plasmin
POIHL- 15596-05 0008 Coagulation, fibrinolysis,
hemostasis and hepatitis - Structural studies and
fractionation of antihemophilic factor (human)
ROlHL-16093-05 Functional properties of hemoglobin and
erythrocytes
** POlHL-16607-05 0005 Calcium ion and control of
cardiovascular function - Chemical modifications of the
sarcoplasmic reticulum membranes (rabbits)
ROlHL-16891-05 The folding of hemoglobin
ROlHL-17494-07 Mechanism of liqand binding to
hemoglobin (human)
POlHL-17813-04 0008 Lung disease and the oxygenation
of blood and tissue - Pulmonary regulation of systemic
blood pressure (human, rabbits, rats)
** ROlHL-18634-03 Quarternary structure of erythro and
chlorocruorins (invertebrates)
ROlHL-20464-01 Regulation of cardiac and skeletal
muscle contraction (mammals)
R23HL-21328-02 The I blood group antigen of human
erythrocyte membrane
R23HL-21488-01 Myosin-linked regulation in vertebrate
smooth muscle (calf aorta)
ROlHL-22270-01 Platelet glycoprotein (human)
ROlHL-22401-01 Regulation of tension and active state in
the heart
CHEMICAL REACTION SITES, ISOSTERIC SITES
R23HL-19573-01 Studies on pulmonary serotonin (mice)
CHEMICAL REACTION SITES, PROTECTIVE
GROUPS
POlHL-16607-05 0005 Calcium ion and control of
cardiovascular function - Chemical modifications of the
sarcoplasmic reticulum membranes (rabbits)
CHEMICAL REACTIONS (DYNAMICS)
SEE ALSO ACYLS, ACYLATION
SEE ALSO ALKYL (GROUPS), ALKYLATION-OEALKYLATION
SEE ALSO AMIDES, AMIDATION
SEE ALSO BIOENERGETICS, HIGH ENERGY COMPOUNDS
SEE ALSO CARBOXYL GROUPS, CARBOXYLATION
SEE ALSO CHEMICAL SYNTHESIS AND PRODUCTION
SEE ALSO ENZYME MECHANISMS
SEE ALSO ESTERIFICATION
SEE ALSO MOLECULAR CONDENSATIONS
SEE ALSO MOLECUUR INTERACTIONS NONBONDING
SEE ALSO OXIDATION-REDUCTION
SEE ALSO PHOSPHORYLATION
NOlHB-62962-02 Red cell distributions in cyanate-treated
blood (human, sheep)
ROlHL-01974-24 Ion-pump in the eiythrocyte (rabbits,
guinea pigs)
ROlHL-04457-20 Cellular aspects of active transport (fish,
rabbits, anurans, turtles)
ROlHL-05556-19 Proteins, lipoproteins-Structure and
reactivity (chicken, human, diving mammals)
ROlHL-07451-16 Hemoglobin S gelation and hemoglobin
allostery (human)
POlHL-08214-15 0027 Chemical and biological properties
of lipids - Biological functions diol lipids (swine, rats.
plants)
(contd)
•eadudn routine mathodoloo OR covers only general projects which preclude Indexing at the specific level.
•-jf/siUS s.:nlfic«nlly to alnve tubject.
M Grant has subprajects describing specific research aspects.
See Appendix tor investigator's name and grant number.
CHE
147
CHE
POIHI 08214 )!> 0041 Ch«mic<l and biological proparllas
ol lipids Phyticochamical reiulalion ol «norni«s in lipid
mtlabollsm
POIHI II3S1 1? 000« Callulai and moleculai
mechanisms ol myocaidial lunclion Molecular physiolojiy
and energetics ot muscle (liogs)
POIHI 113bl 12 0019 Cellular and molecular
mechanisms ol myocardial (unction Mechano chemical
kinetics ot small perturbations
POIHL 11351 12 0024 Cellulai and molecular
mechanisms ot myocardial lunction Steady state and
transient kinetics ol liog myosin. SI. and AlPase
ROIHl 122!>6 IS Pohimeriialion ot sicklecell hemoglobin
(human)
ROIHl 131S7 09 Molecular oxygen earners Synthesis,
structure, bonding
ROIHI 13412 1/ Synthetic oxygen carriers
ROIHI IMSSOb Rheology ot pulmonary secretions (dogs)
POIHL Ibl94 0; 0006 Pathophysiology ot
cardiopulmonary dysfunction Kinetics ot gas exchange
Velocity ol Bohr effect in erythrocytes (human)
POIHL 15194 07 0009 Pathophysiology of
cardiopulmonary dysfunction Kinetics ot gas exchange-
Diffusion and eiythfocytes reaction lates (human, dogs)
POIHL 1519407 0022 Pathophysiology of
cardiopulmonary dysfunction Kinetics of gas exchange
Pulmonary carbon dio de exchange (dogs)
POIHL 1519504 0001 Program project in biological
materials Design and synthesis
ROIHL 1546006 Molecular adaptation- Hemoglobin
systems of fish (marine)
ROIHL 1552805 Renin kinetics in hypertensive and
uremic plasma (human, dogs)
ROIHL 15640 06 Thermodynamic studies on model oxygen
carriers
P60HI- 16008 06 0017 Wayne State University
comprehensive sickle cell center Oxygen transport kinetics
of pre- and post sickling cells (human)
POlHl-161 17-05 0003 Ion movements and membranes in
cardiovascular control Fast kinetic study of calcium
membrane interactions
ROIHL'16355'05 Reactions of thrombin and collagen with
platelets (human)
ROlHL-164 19-03 Arterial uptake of lipoprotein -Kinetic
analysis (rabbits)
ROlHL-16474-05 Antibiotic-ion interactions (model
membranes)
R01HL17494-07 Mechanism of liqand binding to
hemoglobin (human)
ROlHL-17828-04 Kinetic studies of hemerythrin reactions
(marine worms)
ROlHL-18179-03 Heart, platelet, and muscle myosins and
actomyosins (cattle)
ROlHL-18245-03 Transition state analog inhibitors of
thrombin (human, cattle)
POlHL-18577-03 0003 Lipoproteins-Cell surface
interactions - Mechanism of lipid exchange in lipoproteins
and cell membranes
R01HL-18736-03 Protein transport through arterial tissue
(rabbits)
ROlHL-18905-04 Acquisition of native conformation of
proteins (human, cattle)
ROlHL-19459-03 Dynamics of atherogenesis and
lipoprotein formation (human, rabbit)
POlHL-19737-02 0008 Cellular and molecular aspects of
respiratory physiology - Kinetics of movement of acid
metabolites from cell to capillary blood (dogs)
ROlHL-20262-02 Cardiac glycosides and the mechanism
of the sodium-potassium pump
ROlHL-20365-03 Molecular mechanisms of anion transport
POlHL-20592-02 0001 Cell biology of cardiac and
skeletal muscle - Molecular mechanism of muscle
contraction (animals)
ROlHL-20711-01 Structure-function relationships in red
cell NA-K pumps (goats)
POlHL-20984-02 0002 Cellular mechanisms in cardiac
hypertrophy - Thermodynamic, fluorescence, chemical
modification of hypertrophied heart myosin
POlHL-20984-02 0003 Cellular mechanisms in cardiac
hypertrophy - Fast-kinetics of myosin ATPase from normal
and hypertrophied heart (rabbits)
R01HL-2099e-02 Structural and reactivity of iron and
cobalt complexes
Sickle cell anemia and other
Kinetics of sickling
Sickle cell anemia and other
Ligand kinetics in normal and Hb S
containing erythrocytes (human)
ROlHL-21483-01 Electronic, thermodynamic and kinetics
of hemoglobin
R23HL-21488-01 Myosin-linked regulation in vertebrate
smooth muscle (calf aorta)
R01HL-22136-02 Histamine and cardiac adenyl cyclase
** ROlHL-22955-01 inetics of prothrombin activation
** ROlHL-23267-01 Rheology and kinetics of hemoglobin S
gelation (human)
CHEMICAL REACTIONS, BROWNING REACTION
ROlHL-19454-02 Rheological factors in transport across
arterial wall (dogs)
CHEMICAL REACTIONS, CATALYSTS
SEE ALSO ENZYMES
POlHL-2 1016-02 0004
hemoglobinopathies
POlHL-21016-02 0005
hemoglobinopathies
ROIHI 1566806 Ixtiacorpoieii reipliltory |a\ eii hangn
A new approach (dogs)
ROIHI 22258 01 Niiw atpoct% ol pharmacology related to
r^rhonK fiiiliydiAMt
CHEMICAL REACTIONS, DISSOCIATION
Sff AISU lUNI/AllUN
ROIHI 0/451 16 Hemoglobin S gelation and hemoglobin
alloslery (human)
ROIHL 13035 08 Heart mitochondrial malate
dehydrogenase regulation
ROIHL 14938 06 Contractile proteins ot heart muscle
(dogs, rabbits)
ROIHL 15284 06 Hemoglobin and myoglobin kinetic
studies (human, animals)
ROIHL 15460 06 Molecular adaptation Hemoglobin
systems of fish (marine)
ROIHL 1564806 Lipid metabolism Transport by lateral
diffusion (human, rabbit, cattle)
ROIHL 164 74 05 Antibiotic ion interactions (model
membranes)
ROIHL 1654904 Cardiotonic steroid NaK ATPase
interactions (cattle)
POIHL 17731 04 0010 Physiological basis of pulmonary
disease Gas exchange kinetics (dogs)
ROIHL 18893 03 Mechanism ol angiotensin action Role of
receptor (rats)
ROIHL 19456 03 Immunoglobulins associated with serum
hyperviscosity (human)
ROlHL-19488-03 Picosecond laser studies of heme-
proteins
ROlHL-19491 03 Mechanism of iron storage and
mobili2ation by ferritin (horse)
ROIHL 19982 02 Blood coagulation-Proteln-metal ion lipid
interactions
** POlHL-2 10 16-02 0006 Sickle cell anemia and other
hemoglobinopathies - Analysis of the oxygen dissociation
curve of Hb S-containing red cells
ROlHL-211 13-01 Control mechanisms in coagulation
(cattle)
R01HL21791 01 Precipitation of proteins with poly
(ethylene glycol) (human)
R23HL-220 11-01 Adrenergic receptor cyclase system in
sensitized lung (rats, guinea pigs)
ROlHL-22570-01 Interactions of sterols in biological
systems (human)
CHEMICAL REACTIONS, HYDRATION
ROlHL-151 55-05 Rheology of pulmonary secretions (dogs)
POlHL-15195-04 0003 Program project in biological
materials Mechanical evaluation and fabrication
ROlHL-177 76-04 Pulmonary mucus transport in
obstructive lung diseases (human)
ROIHL- 179 63-04 Human erythrocyte carbonic anhydrase
** ROlHL-18441-03 Guidelines for polymers acting as elastin
substitutes
ROIHL 1932003 Angiotensin neuropharmacology-
Relationship to sodium
ROlHL-19700-03 Deposition of hygroscopic aerosols
(models)
ROlHL-19704-03 Aerosol therapy (models, dogs, human)
ROlHL-197 15-02 Respiratory tract deposition of
hygroscopic aerosols (dogs, human)
ROlHL-19722-03 Aerosol growth in the respiratory system
(models)
ROlHL-20024-03 Therapeutic aerosols-Characteristics and
retention (human, dogs)
ROlHL-20105-02 Deposition of hygroscopic aerosols in
bronchi (dogs, human, models)
CHEMICAL REACTIONS, HYDRATION,
DEHYDRATION
ROlHL-17963-04 Human erythrocyte carbonic anhydrase
CHEMICAL REACTIONS, HYDROXYLATION
PGlHL-08899-14 0062 Tolerance to respiratory gases in
health and disease - Influence of oxygen at high pressure
upon oxidation (rats)
'* ROIHL-10894-12 Intestinal bacteria and steroid
metabolism (human, guinea pigs, rabbits, rats)
ROlHL-136 19-09 Microsomal electron transport in liver
and heart (human, mammals)
ROlHL-1 50 13-07 Lung oxidative metabolism and energy
production (rodents, rabbits)
ROlHL-16471-05 Cardioactive alloyohimbines and related
indole alkaloids
ROlHL-178 18-05 Metabolism of cholesterol and cholesterol
in man (also rats, monkeys)
R01HL-19654-03 Biochemical-pharmacological evaluation
of lung cells (rabbits)
ROlHL-201 76-02 Biochemistry and genetics of salt
hypertension (rats)
CHEMICAL REACTIONS, SOLVOLYSIS
ROlHL-1 14 18-09 Poly-diaminophosphazenes
CHEMICAL REACTIONS, SOLVOLYSIS,
HYDROLYSIS
SEE ALSO HYDROUSES
ROlHL-01662-25 Equilibria in the fibrinogen-fibrin
conversion (human, cattle)
POlHL-06285-18 0210 Cardiovascular-respiratorv
physiology and biochemistry - Physicochemical and
enzymatic studies of lung surfactant (Halobacterium)
Metabolism of trans fatty acids (human.
Stabilized prostacyclins to treat vascular
^Excludes mutlne methodotogy OR covers onhr general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojeds describing specific research aspects.
See Appendix for investigator's name and grant number.
POIHI 0R2I4 IS 0041 Chemical and bwloiiial piupMlir-.
of lipids Phynico chnmiral rrgulatton of en/ymv. <n lipid
meliibuliMn
POIHI lll'il 12 002? Cellular and molecular
mnchflnl•vrn^ of myorardial function (nergelir -.rquclae ol
shortrning Myolhermal and biochemical (tiogi)
POIHI in'il \? 0023 Cellular and molecular
inechani'.m^ of myocardial function [nergetici ol
mammalian muscle (rats)
P50HI 1423/ 0/ 0001 Support for arterioicleroiii center
Role ol apohpoproteins in lipoprotein calabolitm (human.
rats)
POIHL 14388 07 0173 Regulation of the circulation in
pathological states Mechanism-, ol cardiac myosin ATPase
ROIHL 15391 0/ EPR studie-. on rotational motion ol
myosin and actin
ROIHL 1817903 Heart, platelet, and muscle myot.m-. and
actomyosins (cattle)
ROIHL 1914803 Myocardial organelle lipid structure and
lunction (dog. rat)
ROIHL 19378 03 Relation of mitochondrial changes to
cardiac failure (dogs, rats)
ROIHL 20079 02 0001 Thromboresistant material Active
and passive thromboresistant surfaces
R23HL 21488 01 Myosin linked regulation in vertebrate
smooth muscle (calf aorta)
R01HL2151302
rats, swine)
ROIHL 2261201
disease
R23HL-22799 01 Interaction of the complement and
coagulation systems (monkeys)
CHEMICAL REACTIONS, SUBSTITUTION
ROIHL 16093-05 Functional properties of hemoglobin and
erythrocytes
ROIHL- 17896-03 Dehydropeptidc renin substrates
CHEMICAL REACTIONS, SUBSTITUTION,
ISOMORPHOUS
** ROlHL-14680-07 Specific enrichment of myoglobins (or
carbon 13 NMR (catacea)
CHEMICAL REACTIONS, SUBSTITUTION,
NUCLEOPHILIC
POlHL-20994-02 0004 Dynamics of neutrophil elastase in
the lung - Mechanism of enzyme inhibition by alpha-1
antitrypsin (cattle)
CHEMICAL STABILITY
SEE ALSO TEMPERATURE, HEAT STABILITY-LABILITY
ROlHL-08893-14 Structure and function of membrane
proteins (human)
ROlHL-12256-15 Polymerization of sickle-cell hemoglobin
(human)
ROIHL-16927-05 Structure and function of normal and
abnormal hemoglobin (human)
ROlHL-18619-03 Transferrin iron binding and transport
properties (chicken, rabbit, human)
ROlHL-18905-04 Acquisition of native conformation of
proteins (human, cattle)
ROlHL-19491-03 Mechanism of iron storage and
mobilization by ferritin (horse)
ROlHL-22538-01 Myosin as a multi-enzyme complex (dogs.
rabbits)
CHEMICAL STIMULATION
SEE DRUGS. PHARMACOLOGY. STIMULATION. CHEMICAL
CHEMICAL STRUCTURE
SEE ALSO CARBOHYDRATES STRUCTURE
SEE ALSO CARBOHYDRATES STRUCTURE. SUGAR SEQUENCE
SEE ALSO CHEMICAL REACTIONS. SUBSTITUTION.
ISOMORPHOUS
SEE ALSO GLOBULINS. GAMMA GLOBULINS,
IMMUNOGLOBULIN STRUCTURE
SEE ALSO HEMOPROTEINS STRUCTURE
SEE ALSO LIPIDS STRUCTURE
SEE ALSO NUCLEIC ACIDS STRUCTURE
SEE ALSO PORPHYRINS STRUCTURE
SEE ALSO PROTEINS-PEPTIDES STRUCTURE
POlHL-06285-18 0211 Cardiovascular-respiratory
physiology and biochemistry - Purple membrane of
Halobacteria
** POlHL-06285-18 0212 Cardiovascular-respiratory
physiology and biochemistry - Membrane structure and
function-Gap junction (bovine)
" POlHL-06285-18 0214 Cardiovascular-respiratory
physiology and biochemistry - Membrane structure and
function-EM of macromolecules
** POlHL-06314-17 0050 Immunologic mechanisms in
cardiovascular disease - Physiologic changes in
lymphocytes (human, mice)
POlHL-06835-17 0064 Cardiovascular disease - Studies
in atherosclerosis (human, animals)
POlHL-08214-15 0010 Chemical and biological properties
of lipids - Infrared spectroscopy of lipids
POlHL-08214-15 0041 Chemical and biological properties
of lipids - Physico-chemical regulation of enzymes in lipid
metabolism
POlHL-08214-15 0048 Chemical and biological properties
of lipids - Lipids in microorganisms and plants
(contd)
CHE
POlHL-08805-15 0048 Regulation of ventilation and
pulmonary circulation ■ Permeability of alveolo-Capillary
membrane in normal pulmonary hypertensive lung
" POlHL-1 1351-12 0004 Cellular and molecular
mechanisms of myocardial function ■ Molecular
mechanisms of contractile function and differentiation
(animals)
** ROlHL-12395-10 X-ray study of oxygen-carrying cobalt
complexes
ROlHL-12528-10 NMR relaxation of liquid crystal systems
R01HL12684-09 Angiotensin I and converting enzyme in
hypertension (human, primates, dogs)
ROlHL-14111-07 Cholesteryl esters in membranes and
atherosclerosis (human, swine)
P50HL-14236-05 0001 Prevention of premature
arteriosclerosis - Metabolism and transport of cholesterol
and vitamin A (human, rats)
ROlHL-15104-07 A mechanism for oxidative
phosphorylation
M POIHL 15195-04 Program project in biological materials
POlHL-15195-04 0002 Program project in biological
materials Structural and surface characterization
POlHL-15195-04 0003 Program project in biological
materials - Mechanical evaluation and fabrication
POlHL-15596-05 0003 Coagulation, fibrinolysis,
hemostasis and hepatitis - Plasmin degraded fibrinogen
fractions (human)
POlHL-15596-05 0007 Coagulation, fibrinolysis,
hemostasis and hepatitis - Structural studies and
fractionation of urokinase (human)
** POlHL-15596-05 0008 Coagulation, fibrinolysis,
hemostasis and hepatitis - Structural studies and
fractionation of antihemophilic factor (human)
POlHL-15835-06 0007 Study of muscles related to heart
disease Structure and function of Limulus striated and
cardiac muscle
** POlHL-16137-05 0001 Alveolar biology - Chemical
characterization of surfactant system-Lipid and lipid
protein fractions
** ROlHL-16150-05 Primary structure of prothrombin (cattle,
human)
POlHL-16683-04 0002 Function and growth of cardiac
and skeletal muscle - Myosin, actio, ATP, interaction in
solution
ROlHL-16746-04 Design of ion-selective molecules
M POlHL-16833-04 Hemoglobin and red cell system in
hemoglobinopathies
POlHL-16833-04 0001 Hemoglobin and red cell system in
hemoglobinopathies - Motility, association and ligand
binding in hemoglobin -Hydrogen exchange
" ROlHL-17376-04 Analysis of Z bands in heart by optical
diffraction (mammals)
POlHL-17382-05 0003 Chemical mediators of acute
pulmonary disorders - Chemical mediators relevant to
allergic reactions (human, guinea pigs)
ROlHL-17799-02 The presence and significance of heart
acetylcholine (cats)
** ROlHL-18253-03 Structure of the palytoxins
** ROlHL-18308-03 Comprehensive studies of mucociliary
transport (dogs)
** POlHL-18576-03 0002 Thrombosis research program
project - Molecular basis of fibrin formation (human, cattle,
lamprey)
** POlHL-18708-03 0003 Oxygen, energy and contractility in
cardiac tissue - Structural-functional studies on cytochrome
c oxidase
" POIHL 18708-03 0004 Oxygen, energy and contractility in
cardiac tissue - Structural-functional studies on
sarcoplasmic reticulum (rabbits)
POlHL-18827-02 0002 Platelet vessel wall interactions In
thrombogenesis - Interactions of vessel wall
macromolecules with factor XII (human, rats)
** POIHL 19259-03 0001 Digoxin-specific antibody in human
therapy - Primary structure of monoclonal antibodies
(rabbits)
ROIHL 19419 03 Cellular interactions with foreign
materials (mammals)
R01HL20500-02 Diabetic human brain microvascular
basement membrane (human)
POlHL-20948-02 0001 Molecular basis of cholesterol
metabolism - Biochemical and ultrastructural
characterization of LDL in human fibroblasts
R23HL-21051-02 Adrenergic receptors and the adenylate
cyclase system (frog RBC)
R23HL 21328-02 The I blood group antigen of human
erythrocyte membrane
ROlHL-21673-01 Pathophysiology of venous changes in
hypertension (rats, rabbits, human, dogs)
R01HL21764-01 Ultramicroanalysis of prostaglandins and
related compounds (rats)
ROlHL-2 1769-01 Blood compatible benzamidine containing
polymers
R01HL21779-01 Steroids in adrenal regeneration
hypertension (rats)
ROIHL 21791-01 Precipitation of proteins with poly
(ethylene glycol) (human)
ROlHL-22077-01 Vasoactive amine disposition in cultured
endothelium (rabbits)
** ROlHL-22201-01 Pharmacology and chemistry of
nudibranch toxins (guinea pigs, rats, mice)
MB
POlHL-22633-01 0004 Cellular and molecular biology of
lipoprotein metabolism - Lipid-lipid and lipid-protein
interactions in serum lipoproteins (human, rats)
ROlHL-22955-01 inetics of prothrombin activation
ROlHL-23183-01 Voltage dependent conductance in
membranes
NOlHV-32917-08 Materials development and testing
CHEMICAL STRUCTURE, CHAIN LENGTH
ROlHL-15958-06 X-ray diffraction analysis of thrombin
and neurotoxin
P60HL-1 7269-04 0016 National heart and blood vessel
researcii and demonstration center - New analytical
methodology for atherosclerosis studies
ROlHL-17995-04 Cellular synthesis and release of
mucopolysaccharides (rabbits)
R23HL-228 18-01 Biosynthesis of human respiratory
mucous glycoprotein (also dog)
CHEMICAL STRUCTURE, ISOMERS
POlHL-06835-17 0061 Cardiovascular disease - Studies
in renal physiology (human, rats, dogs)
ROlHL-07451-16 Hemoglobin S gelation and hemoglobin
allostery (human)
POlHL-082 14-15 0006 Chemical and biological properties
of lipids ■ Analysis and properties of lipids
POlHL-082 14-15 0023 Chemical and biological properties
of lipids - Lipids in microorganisms and cell cultures
(hamsters, mosquitoes)
ROlHL-12879-09 0005 Pulmonary transport and
metabolism in vivo - Glucose transport by pulmonary
endothelium and epithelium (dogs)
ROlHL-15892-05 Inhibitors of proteinases (human, cattle,
swine)
P60HL-17269-04 0016 National heart and blood vessel
research and demonstration center ■ New analytical
methodology for atherosclerosis studies
POlHL-17813-04 0008 Lung disease and the oxygenation
of blood and tissue - Pulmonary regulation of systemic
blood pressure (human, rabbits, rats)
ROlHL-22607-01 Role of apolipoprotein E in lipoprotein
metabolism (human)
CHEMICAL STRUCTURE, ISOMERS, CIS-TRANS
ISOMERIZATION
ROlHL-03941-18 Uterine blood flow and changes in
pregnancy (sheep)
ROlHL-18239-03 Dietary fat composition and
prostaglandin synthesis (rats)
** ROlHL-2151302 Metabolism of trans fatty acids (human,
rats, swine)
CHEMICAL STRUCTURE, ISOMERS,
STEREOISOMERS (GENERAL)
ROlHL-19772-02 Role of warfarin metabolism in
antivitamin K activity (rats)
CHEMICAL STRUCTURE, MOLECULAR SHAPE
SEE ALSO CHEMICAL STRUCTURE, STEREOCHEMISTRY
R01HL17976-18 Chemical agents and heart glycolytic
enzymes (sheep)
P50HL-191 90-02 0005 Pulmonary SCOR-Pathophysiology,
management of IRDS • Glycoproteins in mucous secretions
(human, cattle)
CHEMICAL STRUCTURE, STEREOCHEMISTRY
SEE ALSO CHEMICAL STRUCTURE, ISOMERS
POlHL-082 14-15 0030 Chemical and biological properties
of lipids - Fatty acid biosynthesis in plant cell cultures and
in plants
POlHL-12157-11 0037 Functions and mechanisms of cell
membrane ion transport - Developing structure of heart
cells in tissue culture
** ROlHL-12740-10 Hypocholesterolemic agents-
Stereochemistry (rats)
ROlHL-1341217 Synthetic oxygen carriers
P60HL-151 57-07 0011 Comprehensive center for sickle
cell disease - Development of specific anti-sickling
compound (human)
** ROlHL-15376-05 Intermediary metabolism of sterols (mice)
** ROlHL-15527-06 X-ray and chemical studies of
metalloporphyrins
P60HL- 16005-05 0015 Comprehensive sickle cell center -
Molecular basis for the sickling phenomenon
ROlHL-1608705 Structural and dynamic study of model
heme complexes (yeast)
R01HL1647105 Cardioactive alloyohimbines and related
indole alkaloids
ROlHL-1652402 Selective inhibitors of prostaglandin
biosynthesis (dogs)
** POlHL-16833-04 0015 Hemoglobin and red cell system in
hemoglobinopathies ■ Stereochemistry of hemoglobins from
magnetic circular dichroism (human)
R01HL16927-05 Structure and function of normal and
abnormal hemoglobin (human)
R01HL17897-03 Synthesis of alpha and beta adrenergic
antagonists
ROlHL-188 18-04 Stereochemical mechanism of sickling of
hemoglobin S (human)
ROlHL-2136702 Polyether ionophores -Synthesis of X537A
and analogs
ROlHL-227 78-01 Total synthesis of natural cardiotonic
ionophores
•Excludes routine melhodotogy OR covers only general projects which preclude
•♦Oneirted significantly to above subject.
Indexing at the specific level.
M Grant has subprojects descnbing s
See Appendix for investigator's name
CHE
CHEMICAL STRUCTURE, STEREOCHEMISTRY,
CONFORMATIONS
SEE ALSO CHEMICAL REACTION SITES, ALLOSTERIC SITES
SEE ALSO CHEMICAL REACTION SITES. ISOSTERIC SITES
ROlHL-02212-23 Coagulation of blood (human)
ROlHL-05791-18 Structure and function in hemoglobins
(human)
POlHL-06285-18 0173 Cardiovascular-respiratory
physiology and biochemistry - Skeletal and cardiac muscle
function
** POlHL-06285-18 0215 Cardiovascular-respiratory
physiology and biochemistry - Conformation of biopolymers
** POlHL-06314-17 0051 Immunologic mechanisms in
cardiovascular disease - Conformational studies of
phospholipid membranes and proteins
POlHL-06835-17 0030 Cardiovascular disease - Synthesis
and pharmacology of angiotensin antagonists (rats, cats)
** POlHL-06835-17 0033 Cardiovascular disease - Structure-
activity relationship of angiotensin II analogs (rats)
ROlHL-07451-16 Hemoglobin S gelation and hemoglobin
allostery (human)
P01HL08214-15 0040 Chemical and biological properties
of lipids - Nuclear magnetic resonance studies of lipids
ROlHL-08299-16 Molecular biology of hemerythrin and
hemocyanin (invertebrates)
POlHL-11310-12 0101 Mechanisms of cardiovascular
disease - Molecular pathogenesis of vascular disease
POlHL-11310-12 0102 Mechanisms of cardiovascular
disease • Cardiac membrane and ion mobility (dogs)
POlHL-11310-12 0103 Mechanisms of cardiovascular
disease - Heparin-Metabolism and function
ROlHL-11822-10 Biophysical studies of macromolecular
interactions (microorganism, human)
ROlHL-11963-10 Biochemistry of blood vessel formation
and disease (swine)
ROlHL-12524-10 Reaction of hemoglobin with ligands and
antibodies (human, carp)
POlHL-13262-07 0015 Arterial wall in atherosclerosis -
Crosslinkage biosynthesis in aortic elastin and collagen
(animals)
ROlHL-13423-08 Structure-function studies of plasminogen
and plasmin (human)
ROlHL-13870-09 Control of myocardial sarcotubular
calcium stores (dogs)
ROlHL-13909-27 Physiochemistry and immunology of
macromolecules
P50HL-14147 08 0015 Specialized center of research in
thrombosis - Charge related properties of phospholipid
surfaces in monolayers and vesicles
P50HL 14217-08 0062 Specialized center of research in
thrombosis - Coagulation section -Factor VIII and Factor XII
(human, cattle)
P50HL-14237-07 0003 Support for arteriosclerosis center
- Structure of lipoproteins and apolipoproteins (human,
rabbits)
POlHL-14388-07 0173 Regulation of the circulation in
pathological states - Mechanisms of cardiac myosin ATPase
ROlHL-14509-07 Hypertension-Chemistry and biophysics
of angiotensin
P50HL-1506207 0007 Study of lipoproteins, artery wall,
and atherosclerosis - Physical chemistry of lipid-protein
interaction (human)
P60HL-15157-07 0018 Comprehensive center for sickle
cell disease - Red blood cell membrane physiology in sickle
cell anemia (human)
** POlHL-15195-04 0002 Program project in biological
materials - Structural and surface characterization
POlHL-15195-04 0003 Program project in biological
materials - Mechanical evaluation and fabrication
ROlHL-15378-06 Ultrastructure of antihypertensive
prostaglandins
ROlHL-15391-07 EPR studies on rotational motion of
myosin and actin
** P01HL15596-05 0017 Coagulation, fibrinolysis,
hemostasis and hepatitis - Heparin and antithrombin III
ROlHL-1 5692-07 Force and speed in skeletal and cardiac
muscle
ROlHL-15808-06 Role of angiotensinogen in hypertension
and stroke (human, rabbits)
POlHL-15835-06 0001 Study of muscles related to heart
disease - Control of contraction-relaxation of heart and
muscle (rabbits, chickens)
POlHL-15835-06 0007 Study of muscles related to heart
disease - Structure and function of Limulus striated and
cardiac muscle
ROlHL-1610105 Protein-lipid interaction (bacteria,
models)
POlHL-161 17-05 0006 Ion movements and membranes in
cardiovascular control - Neuroreceptors and cellular
excitation (fish)
POlHL-16137-05 0001 Alveolar biology - Chemical
characterization of surfactant system-Lipid and lipid
protein fractions
ROlHL-16318-21 Biochemistry and pharmacology of Na-K
transport
** R01HL-16375-04 Investigation of hemoglobin S properties
(human)
POlHL-16411 04 0003 Blood systems in coagulation and
vessel disease - Molecular events involving the late stages
of coagulation (rabbits)
ROlHL-16601-05 Structure and function of blood proteins
(human, cattle)
(contd)
pecitic research aspects,
and grant number.
CHE
POIHL 16607 OS OOOS Cilclum ion ind contiol ol
ctidloviKuUi function ChemlctI modltlcitions ot lh«
strcopiismic iitlculum mem bunts (((bblts)
POIHl 16607 OS 0006 Calcium Ion tnd conliol ol
ciidiovisculii function Siicomtio and contiactil*
dynamics ol sliiated musci* calls (animals)
'* POIHL 16607 OS 0007 Calcium ion and control of
caidiovtsculai function Ultiastiucluia and confoimation
In saicoplasmic leticulum (labbits)
POIHL 16683 04 0001 Function and growth ol caidiac
and skeletal muscle Light chains ot the skeletal and
cardiac myosin molecule (rabbits, frogs)
POIHL 16833 04 0006 Hemoglobin and red cell system in
hemoglobinopathies Role of water in function of
hemoglobin and myoglobin (human)
•• ROIHL 16891 OS The folding of hemoglobin
P60HL 17269 04 0017 National heart and blood vessel
resairch and demonstration center Cell membrane (dogs.
rabbits)
P60HL 1726904 0019 National heart and blood vessel
research and demonstration center Sarcoplasmic
reticulum (dog. rabbit, hamster, cat)
POIHL 1741904 0007 Studies on mechanisms of
hemostasis Structural analysis ot ordered forms of
fibrinogen (human, cattle)
ROIHL'17494 07 Mechanism of liqand binding to
hemoglobin (human)
R01HL17S13 04 Role of Pf 4 in detecting and promoting
thrombosis (human, primates)
POIHL'18208 04 0007 Center for the study of blood cell
rheology RBC membrane protein (human)
POIHL- 1857403 0005 Lipoprotein methodology and
biomedical applications Structure and function of
lipoproteins
POIHL 18576-03 0012 Thrombosis research program
project - Synthetic anticoagulant and thrombolytic agents
(dogs)
ROlHL-1861203 Thin filament control of heart contraction
(cattle)
** ROlHL-1867203 Dynamic studies of clot structure
formation (human)
** ROlHL-18905-04 Acquisition of native conformation of
proteins (human, cattle)
ROlHL-19488-03 Picosecond laser studies of heme-
proteins
ROlHL-19514-03 Proteinase inhibitor moriel with clinical
potential
P01HL-19717-02 0001 Response of the lung to injury -
Lung elastic tissue (animals)
POlHL-19717-02 0004 Response of the lung to injury -
Regulatory and physical-chemical properties of lung lysyl
oxidase (animals)
** ROlHL-20262-02 Cardiac glycosides and the mechanism
of the sodium-potassium pump
R01HL-20350-02 Crystal structure of lipids-Cholesterol
R01HL-2039I-03 Polydisperse LDL-Structure. metabolism
and function (human)
ROlHL-20750-01 Studies in sickle cell disease (human)
POlHL-20984-02 0001 Cellular mechanisms in cardiac
hypertrophy - Contractile proteins in cardiac hypertrophy
(rabbits, calves)
POlHL-20984-02 0002 Cellular mechanisms in cardiac
hypertrophy ■ Thermodynamic, fluorescence, chemical
modification of hypertrophied heart myosin
P60HL-20985-01 0006 Northern California sickle cell
center - Antisickling properties of imidoesters (human, rats)
POlHL-2101602 0015 Sickle cell anemia and other
hemoglobinopathies - EPR study of NO derivatives of Hb
Beth Israel (human)
ROlHL-2 11 70-01 Molecular structure of human serum
transferrin
** ROlHL-21543-02 Structure-function relation of blood
clotting proteins (rabbits)
R01HL-21791-01 Precipitation of proteins with poly
(ethylene glycol) (human)
ROlHL-22035-01 Molecular modification of heparin by
chemical means (sheep)
ROlHL-22270-01 Platelet glycoprotein (human)
ROlHL-22402-01 Heparln-biophysical. chemical and
biological aspects (mice, human)
ROlHL-22461-01 Cardiac tropomyosin and tropomyosin-
action interactions (rabbit)
R01HL-22530-01 Active site studies on blood proteases
(human)
ROlHL-22570-01 Interactions of sterols in biological
systems (human)
POlHL-22619-01 0004 Cellular mechanisms of heart
failure - Mechanism of action of Na. K-ATPase (sheep.
cattle)
POlHL-22619-01 0005 Cellular mechanisms of heart
failure - Molecular mechanism of regulation of cardiac
muscle contraction (cattle)
POlHL-22619-01 0011 Cellular mechanisms of heart
failure - Reaction of lipoproteins and apolipoproteins with
lipoprotein lipase (cattle)
ROlHL-24021-02 Erythocyte membrane sulfhydrls and Rh
activity (human)
NOlHV-72943-01 Prostaglandin and kallikrein kinin system
antagonists
NOlHV-72944-02 Prostaglandin and kallikrein kinin
antagonists
Structure and function in hemoglobins
Analysis of antiarrhythmic agents (dogs.
Biochemistry of muscle contraction (rats.
149
NOIHV 7294S 03 Onvnlop prostaglandin lynlhoMS and
receptor antagonists
NOIHV 72946 02 Developmnnt ol kallikrein Kiiiin lyittm
antagonists
CHEMICAL STRUCTURE-BIOLOGICAL ACTIVITY
SI I Also BIOASSAy
Sit ALSO IN/yMf STRlJCItlRf
ROIHL 02063 23 Biochemistry and function of lipids and
cell membranes (human, yeast, animals)
ROIHL 02SS8 22 Structure function relationships in the
heme proteins (human, cattle)
ROIHL 02942 22 Biochemistry of cardiovascular connective
tissue (human, cattle, primates)
ROIHL 03919 20 The cell suface of streptococci (rats,
human)
** ROIHL 04366 19 Plasminogen Activation and structure
function relations (mammals, birds)
ROIHL 05168 19 Inhomogencity of hemoglobin types
(human)
ROIHL 05556 19 Proteins, lipoproteins Structure and
reactivity (chicken, human, diving mammals)
ROIHL 05791 18
(human)
ROIHL 05806 18
rabbits)
ROIHL 05949 18
rabbits)
** P01HL06285-18 0182 Cardiovascular respiratory
physiology and biochemistry ■ Structure and function of
vascular chemoreceptors (cats, rats)
POlHL-06285 18 0194 Cardiovascular-respiratory
physiology and biochemistry - Hormonal regulation of
sodium transport -RNA synthesis (rats, toads)
POlHL-06285-18 0210 Cardiovascular-respiratory
physiology and biochemistry - Physicochemical and
enzymatic studies of lung surfactant (Halobacterium)
POIHL 06285 18 0213 Cardiovascular-respiratory
physiology and biochemistry - Membrane structure and
lunction-Gas vacuole membrane (Halobacterium)
** POlHL-06350-17 0020 Hemostasis research program
project - Structure and function of coagulant venom
proteases
POlHL-06370-17 0015 Cardiopulmonary and renal
pathology research center - Pathogenesis of chemically
induced tissue injury (rats)
POlHL-06835-17 0030 Cardiovascular disease ■ Synthesis
and pharmacology of angiotensin antagonists (rats, cats)
" POlHL-06835-17 0033 Cardiovascular disease - Structure-
activity relationship of angiotensin II analogs (rats)
ROlHL-07379-13
(human)
ROlHL-07451 16
allostery (human)
ROlHL-07502-13
(dogs, plants)
M P0IHL-082U-15
lipids
POlHL-082 14-15 0023 Chemical and biological properties
of lipids - Lipids in microorganisms and cell cultures
(hamsters, mosquitoes)
** POlHL-082 14-15 0025 Chemical and biological properties
of lipids - Biosynthesis and biological functions of
plasmalogen (cattle)
** POlHL-082 14-15 0027 Chemical and biological properties
of lipids - Biological functions diol lipids (swine, rats,
plants)
POlHL-0821415 0040 Chemical and biological properties
of lipids - Nuclear magnetic resonance studies of lipids
ROlHL-08299-16 Molecular biology of hemerythrin and
hemocyanin (invertebrates)
ROlHL-08311-14 Effects of drugs upon myocardial hypoxia
(dogs, turtles)
" POlHL-08682-15 0006 Regulation of the cardiovascular
system - Cardiovascular studies of mammalian hibernators
(sciuromorpha)
ROlHL-103 16-13 Structural studies on low density serum
lipoproteins (human)
ROlHL-10383-12 Physical-chemical studies of hemoglobins
and erythrocyte (human)
** POlHL-11310-12 0095 Mechanisms of cardiovascular
disease - Complement chemistry and biology (human,
rabbits)
** POlHL-1 13 10-12 0097 Mechanisms of cardiovascular
disease - Structural-functional relationships of neuronal
differential alloantigens (mice)
POlHL-1 14 14-11 0035 Thrombosis and atherosclerosis
program - Mechanism of action of vitamin K (rats)
** ROlHL-11511-10 Structure of ferritin and its role in iron
metabolism (horse, rats, human)
ROlHL-11963-10 Biochemistry of blood vessel formation
and disease (swine)
ROlHL-12524-10 Reaction of hemoglobin with ligands and
antibodies (human, carp)
** ROlHL-12526-09 Raman spectra of heme proteins and
related molecules
ROlHL-12585-10 Structural properties of malate
dehydrogenase (swine)
ROlHL-12648-09 Catecholamine metabolism in
hypertensive diseases (human)
ROlHL-12740-10 Hypocholesterolemic agents-
Stereochemistry (rats)
ROlHL-12994-09 The Rh complex of red cells (human)
Structure and function of fibrinogen
Hemoglobin S gelation and hemoglobin
Phytochemistry of the genus thalictrum
Chemical and biological properties of
Hypertension -Chemistry and biophysics
CHI
POIHl 13262 07 0023 Arttnal wall in alhiroiclaiotit
Isolation and chaiacltiKalion of tolubl* alaitin
POIMI 13262 0/ 002'j Arttnal wall in ■thatoularotit
Phospholipid and ctioleilerol attar*
ROIHl 13399 16 Htma prolain tiructurt and function
(human, hone, plants, bacteria)
ROIHl 13423 08 Structura function studies of platminogan
and plasmin (human)
ROIHl 1 358 1 II Reactions of oiygen with heme proteins
ROIHl 13636 08 (ffecis of pharmacologic agents on heart
mi'labolism (human, rodents)
ROIHl 13909 2/ Physiochemistry and immunology of
macromoleculus
P50HL 1414/ 08 0018 Specialized center of research in
thrombosis Biochemical aspects of platelet function in
thrombosis and cell growth (human)
P50HL 14192 08 0004 Specialized center of research in
hypertension Isolation and characteri/ation of pure renin
(swine, rats, human, rabbil-^)
P50HL 14217 08 0048 Specialiied center of research in
thrombosis Fibrinolysis section-Structural studies (human.
animal)
P50HL 14217 08 0062 Specialized center of research in
thrombosis Coagulation section Factor VIII and Factor XII
(human, cattle)
P50HL 14230 07 0098 A/S SCOR Lipids, atherosclerosis
and thrombosis Molecular properties of factor VIII (cattle.
human, mice)
P50HL 14237 07 0004 Support for arteriosclerosis center
Synthesis, secretion of normal, abnormal plasma
lipoproteins (rodents, monkeys)
ROIHL 14271 07 Physico-chemical properties of tracheal
mucus (dogs, frogs)
ROIHL 14397-07 Hypertension Angiotensin and
prostaglandin pharmacology (animals)
ROIHL 14508 10 Structure and function of respiratory
hemoproteins
ROIHL 1450907
of angiotensin
ROlHL-14680-07 Specific enrichment of myoglobins for
carbon 13 NMR (catacea)
P50HL-15062 07 0001 Study of lipoproteins, artery wall,
and atherosclerosis - Structure and molecular interactions
of serum lipoproteins (human, monkey)
P50HL-15062-07 0007 Study of lipoproteins, artery wall.
and atherosclerosis • Physical chemistry of lipid-profein
interaction (human)
P60HL-15158-07 0016 Comprehensive sickle cell center •
Biochemical studies in sickle cell anemia (human)
ROlHL-15284-06 Hemoglobin and myoglobin kinetic
studies (human, animals)
ROlHL-15341-06 Lung hormonal and chromosomal
regulation (rats, rabbits)
ROIHL-15378-06 Ulfrastructure of antihypertensive
prostaglandins
■ P50HL 15389-07 0014 Pulmonary SCOR-Hypersensltivity
pneumonitis - Fractionation and characterization of pigeon
antigens
P50HL-15389-07 0015 Pulmonary SCOR-Hypersensitivity
pneumonitis - Fractionation and characterization of
thermophilic Actinomycete antigens
' ROlHL-15427-06 Secretion of plasma lipoproteins (rats)
ROIHL- 15460-06 Molecular adaptation-Hemoglobin
systems of fish (marine)
' ROlHL-15474-06 Structure and function of the
antihemophilic factor (human, cattle)
POlHL-15596-05 0010 Coagulation, fibrinolysis,
hemostasis and hepatitis - Von Willebrand's factor (human)
' ROlHL-15615-06 Structure-function studies of human
factor VIII/vWF
ROlHL-15640-06 Thermodynamic studies on model oxygen
carriers
POIHL- 15832-06 0005 Chemical-structural predispositions
to lung Injury - Pulmonary structure and stress-strain
relationships (rats)
ROlHL-15887-05 Enzymes of blood coagulation and
fibrinolysis (human)
ROIHL- 15958-06
and neurotoxin
ROlHL-15980-06
(cattle)
ROlHL-15991-05
anemones
* ROlHL-16059-06 Structure and function of serum
lipoproteins (cattle, human)
ROlHL-16087-05 Structural and dynamic study of model
heme complexes (yeast)
ROlHL-16093-05 Functional properties of hemoglobin and
erythrocytes
ROlHL-16233-05 Molecular cardiology of MDP-induced left
ventricular failure (dogs)
P01HL-ie251-0e Membrane-bound enzymes in heart and
other tissues
* POlHL-16251-06 0001 Membrane-bound enzymes In heart
and other tissues - Structure of covalently bound flavins
(bacteria, yeast, mammals)
* POlHL-16251-06 0002 Membrane-bound enzymes in heart
and other tissues - Structural basis of regulation of
cardiac succinate dehydrogenase
P01HL-16251-0_6 0003 Membrane-bound enzymes in heart
and other tissues - Regulation of cardiac succinate
dehydrogenase (yeasts, mammals)
(contd)
X-ray diffraction analysis of thrombin
Reactions of hemeproteins and oxygen
Evaluation of heart stimulants in sea
*Excludes mutine methodokigy OR covers only general projects which preclude indexing at the specific leveL
**Orienred slgnificanthr to above subject.
M Grant has subprajects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
CHE
R01HL16318-21 Biochemistty and pharmacology of Na-K
transport
POlHL-16411-04 0005 Blood systems in coagulation and
vessel disease ■ Chemical analysis o1 serum components
associated with coagulation (human, animal)
R01HL16549-04 Cardiotonic steroid-NaK ATPase
interactions (cattle)
•* ROlHL-16601-05 Structure and function of blood proteins
(human, cattle)
ROlHL-16628-05 Regulation of lipid metabolism (rats)
•* R01HL16642-05 Biochemistry and pathophysiology of
plasma liallihrein (human, animals)
ROlHL-16647-05 Studies on the control of sickle cell crisis
(human)
R01HL16660-06 Phospholipidcholesterol and
phospholipidprotein interactions
R01HL16720-02 Platelet aggregation (human)
POlHL-1676905 0002 Pathobiologic and host defense
reactions in the lung - Pathogenesis of complement
dependent injury to the lungs (rabbits)
POlHL-16851-04 0006 Human red cell membrane in
health and disease - Hexose transport and erythrocyte
membrane proteins (human)
R01HL16919-05 Proteins of blood coagulation (human,
bovine)
ROlHL-16927-05 Structure and function of normal and
abnormal hemoglobin (human)
ROlHL-17194-03 Comparison of two inherited forms of
alpha-1-antitrypsin (human)
P60HL-17265-04 0002 Community blood resource center
support - Research-Human factor VIII
** P60HL17265-04 0003 Community blood resource center
support • Research-Human factor IX-Role in intrinsic
clotting (also baboons, dogs)
** P60HL-17269-04 0009 National heart and blood vessel
research and demonstration center - Physical methods
laboratory (high density lipoproteins)
** P60HL-1726904 0017 National heart and blood vessel
research and demonstration center ■ Cell membrane (dogs,
rabbits)
** P60HL-17269-04 0022 National heart and blood vessel
research and demonstration center - Medicinal chemistry
(rabbit, dog, guinea pig)
ROlHL-17364-04 'Big renin-Biochemical and clinical
studies (human)
R01HL17402-04 Mechanism of contact activation of
intrinsic clotting (human)
** POlHL-1743005 0002 Control of coagulation - Isolation
of ristocetin-von Willebrand factor (swine)
ROlHL-17463-03 Composition and structure of plasma
lipoproteins (human, rabbits)
ROlHL-17494-07 Mechanism of liqand binding to
hemoglobin (human)
R01HL17525-03 Molecular basis of collagen-platelet
interaction (human, rat)
RO1HL17555-05 Distribution and metabolism of labeled
digitaloids (dogs, guinea pigs)
ROlHL-17576-04 Role of sphingomyelin in biomembranes
and bilayers (rats, other mammals)
ROlHL-17702-04 Electro-optical dyes as probes of heart
excitability
POlHL-17812-04 0001 Thrombosis and plasma proteins -
Thrombosis and plasma proteins (cattle, guinea pigs)
ROlHL-17898-03 Cell membranes and plasma lipoproteins
(human, swine)
•* ROlHL-17963-04 Human erythrocyte carbonic anhydrase
R01HL18015-03 Pharmacologic studies on vascular
smooth muscle (dogs, rats)
ROlHL-18027-03 New vasoactive factors and their role in
hypertension (human, dogs, rats)
ROlHL-18038-03 Structure and function of heart
mitochondria (cattle)
R01HL18102-02 Role of the adrenal cortex in human
hypertension
ROlHL-18269-03 Controlled intratissue release of
prostaglandins
" P50HL18323-04 0038 SCOR hypertension center ■
Unknown adrenocortical mechanisms in hypertension
(human)
P50HL18323-04 0045 SCOR hypertension center -
Laboratory programs-Prorenin (human)
** R01HL18435-03 Properties of thrombin and Ac-globulin
(human, animals)
POlHL-18576-03 0005 Thrombosis research program
project Molecular basis of von Willebrand's disease and
hemophilia (human, cattle)
** POIHL 18577-03 0001 Lipoproteins -Cell surface
interactions ■ Structural studies of serum lipoproteins in
man and dogs
ROlHL-18612-03 Thin filament control of heart contraction
(cattle)
ROlHL-18619-03 Transferrin iron binding and transport
properties (chicken, rabbit, human)
ROlHL-18623 12 Physical chemistry of biologically active
lipids (bacteria, plant, cattle, human)
ROlHL-18679-04 Synthetic protease inhibitors
R01HL-18737-03 Human erythrocyte membrane structure
ROlHL-18818-04 Stereochemical mechanism of sickling of
hemoglobin S (human)
•• R01HL-18852-03 Biochemical studies on the blood
coagulation process (human, cattle)
*♦ ROlHL-18859-03 Biochemistry of human factor XI (human
150
R01HL-18900-03 Intercellular factors in function of
cardiac cells
ROlHL-18905-04 Acquisition of native conformation of
proteins (human, cattle)
ROlHL-19066-03 Synthesis and evaluation of
prostaglandin metabolites (guinea pigs)
P50HL-191 57-02 0004 Studies in cystic fibrosis and
bronchiolitis Macromolecular regulators of mucus
secretion -Invertebrate model
' P50HL-191 57-02 0007 Studies in cystic fibrosis and
bronchiolitis - Analysis of cystic fibrosis factors (human)
P50HL-191 60-02 0002 Mucus abnormality in cystic
fibrosis - Ultrastructure, cytochemistry of pulmonary
secretion (human, rat)
P50HL-19185-02 0002 Pulmonary SCOR -Neonatal
respiratory distress syndromes - Biochemistry,
ultrastructure -Pulmonary surface active material (human,
animal)
* P01HL19259-03 0002 Oigoxin-specific antibody in human
therapy - Chemical semi-synthesis of digoxin-specific
antibody (rabbits)
ROlHL-19272-03 Studies on the Passovoy factor (human)
ROlHL-19278-03 Ristocetin induced platelet aggregation
(human)
ROlHL-19279-03 Intracellular action of aldosterone in
hypertension (human, rats)
ROlHL-19287-03 The antihypertensive function of the
renal medulla (human, rats, rabbits)
ROlHL-19394-03 Biochemistry and regulation of taurine in
the heart (rats, guinea pigs, cats)
ROlHL-19731-03 Collagen in interstitial fibrosis of lung
(human)
ROlHL-19795-03 Synthesis of anaphylatoxic and
leucotactic peptides (human)
ROlHL-19806-03 Chemotactic control of airway phagocytes
(human, rabbits)
ROlHL-19820-02 The chemistry and biological effects of
heparin (Rhesus, human, other mammals)
ROlHL-19977-02 Genesis of circulatory shock by
pancreatic peptides (cats, dogs)
** ROlHL-20074-02 Structure and function of amidinated
human hemoglobin
** ROlHL-20092-02 Structural and biological properties of
fibrinogen (human, rabbits)
ROlHL-201 61-02 Role of gamma-carboxyglutamic acid in
blood coagulation (human, cattle)
ROlHL-201 76-02 Biochemistry and genetics of salt
hypertension (rats)
ROlHL-20220-03 Anaphylatoxins as inflammatory and
chemotactic agents (guinea pig. rabbit, human)
ROlHL-202 54-02 Probes of heart and nerve membranes-
Fluorescent dyes
ROlHL-20317-02 Procoagulant lipoproteins-Biochemistty
and bioactivity (goats, rabbits)
** ROlHL-20339-02 Vascular alphaadrenergic receptor
molecular properties
ROlHL-20365-03 Molecular mechanisms of anion transport
ROlHL-20517-03 Diabetes, somatotropin, factor VIII and
atherosclerosis (human, animal)
** ROlHL-20577-03 The mechanism of action of vitamin K
ROlHL-20658-01 Myocardial energy transport-Creative
kinase (human, cattle, dog)
*• ROlHL-207 11-01 Structure-function relationships in red
cell NA-K pumps (goats)
ROlHL-20859-02 Beta adrenergic catecholamine receptor
ROlHL-20996-02 Structural and reactivity of iron and
cobalt complexes
** ROlHL-21009-02 Effects of air pollutants on lung cells in
culture (rats)
** R23HL-21208-02 Structure-function relationships of human
factor VI II . . ,
R23HL-21369-02 Tracheal mucin synthesis in experimental
bronchitis (rats)
ROlHL-21404-01 Raman spectroscopy of erythrocyte and
model membranes (human)
R23HL-214 13-02 Structure and function of platelet
calcium-binding protein (human)
** ROlHL-21457-01 C(17)-side group geometry and
cardenolide activity (cats, guinea pigs)
ROlHL-21471-02 Structure-function studies on actin and
myosin (human, protozoa, rabbits, cattle)
ROlHL-21483-01 Electronic, thermodynamic and kinetics
of hemoglobin
** ROlHL-21626-01 Proteoglycans of animal lung
parenchyma (cattle, pigs, rabbits)
** ROlHL-21649-01 Biochemistry of lung proteoglycans
(mammals)
ROlHL-21676-02 Purification and properties of
erythropoietin (human)
ROlHL-21757-01 Elastin structure-DNA breathing-
Hemoglobin S gelation
** ROlHL-21763-09 Heparin and heparan sulfate-Structure
and activity (beef, hog)
ROlHL-21860-18 Factors influencing responses to
adrenergic drugs (guinea pigs, rats, cats)
R01HL-21996-01 Alteration of digitalis and aldosterone
disposition (rats, rabbits, mice, dogs)
** ROlHL-22035-01 Molecular modification of heparin by
chemical means (sheep)
ROlHL-221 15-02 Lipid-mobilization and diabetic
atherosclerosis (human)
CHE
** ROlHL-22119-01 Biochemistry of platelet function in
thrombosis and cell grovrth (rabbits)
ROlHL-22136-02 Histamine and cardiac adenyl cyclase
** ROlHL-22201-01 Pharmacology and chemistry of
nudibranch toxins (guinea pigs, rats, mice)
ROlHL-22252-01 Synthesis of labeled hemes for protein
NMR studies
** ROlHL-22288-01 Renin and precursors-Structure and
function (mice)
" ROlHL-22402-01 Heparin-biophysical, chemical and
biological aspects (mice, human)
ROlHL-22522-01 Cardioselectivity of beta-ad renoceptor
antagonists
** ROlHL-22555-01 Structure and function of platelet
activating factor (rabbits, human)
POlHL-22619-01 0002 Cellular mechanisms of heart
failure - Structure of sodium, potassium-adenosine
triphosphatase (lambs, dogs)
** POlHL-22633-01 0003 Cellular and molecular biology of
lipoprotein metabolism Sterol metabolism in platelets and
megakaryocytes (human, rabbits, guinea pigs)
ROlHL-22682-01 Structure and function of high density
lipoprotein (human, rat)
** ROlHL-22875-01 Crotalase -Chemistry, physiology, clinical
potential (rats, rabbits)
ROlHL-23233-01
structure (cattle)
NOlHR-52957-02
(human, swine)
NOlHR-72920-01
factors (human)
Pulmonary artery intermediate filament
Composition of respiratory mucus
Identify and quantify cystic fibrosis
CHEMICAL STRUCTURE OF CARBOHYDRATES
SEE CARBOHYDRATES STRUCTURE
CHEMICAL STRUCTURE OF HEMOPROTEINS
SEE HEMOPROTEINS STRUCTURE
CHEMICAL STRUCTURE OF PORPHYRINS
SEE PORPHYRINS STRUCTURE
CHEMICAL SYNTHESIS AND PRODUCTION
SEE ALSO BIOLOGICAL PREPARATIONS AND STANDARDIZATION
SEE ALSO DRUGS SYNTHESIS AND PRODUCTION
SEE ALSO ENZYME RECONSTITUTION
POlHL-06285-18 0215 Cardiovascular-respiratory
physiology and biochemistry - Conformation of biopolymers
POlHL-08214-15 0027 Chemical and biological properties
of lipids - Biological functions diol lipids (swine, rats,
plants)
** ROlHL-11418-09 Poly-diaminophosphazenes
ROlHL-12395-10 X-ray study of oxygen-carrying cobalt
complexes
POlHL-12738-10 0114 Physiologic pharmacology and its
clinical applications - Receptor specificltes and metabolism
of neurohypophysial hormones (rats)
R01HL-I2740-10 Hypocholesterolemic agents-
Stereochemistry (rats)
** ROlHL-13160-08 Human thrombin (also cattle)
** ROlHL-13412-17 Synthetic oxygen carriers
ROlHL-13581-11 Reactions of oxygen with heme proteins
** ROlHL-13587-06 Synthesis of renin inhibitors and analog
phosphatides (rats)
ROlHL-14508-10 Structure and function of respiratory
hemoproteins
P50HL-1 5062-07 0021 Study of lipoproteins, artery wall,
and atherosclerosis - Core laboratories
** POlHL-15195-04 0001 Program project in biological
materials - Design and synthesis
POlHL-15195-04 0003 Program project in biological
materials - Mechanical evaluation and fabrication
ROlHL-15376-06 Intermediary metabolism of sterols (mice)
R01HL-I5640-06 Thermodynamic studies on model oxygen
carriers
POlHL-16251-06 0001 Membrane-bound enzymes in heart
and other tissues - Structure of covalently bound flavins
(bacteria, yeast, mammals)
ROlHL-16346-09 Enzyme assay for blood clotting (human)
ROlHL-16471-05 Cardioactive alloyohimbines and related
indole alkaloids
** ROlHL-16746-04 Design of ion-selective molecules
ROlHL-16921-05 Synthetic hydrogels as blood tolerable
materials
P60HL-17269-04 0009 National heart and blood vessel
research and demonstration center - Physical methods
laboratory (high density lipoproteins)
** P60HL-17269-04 0022 National heart and blood vessel
research and demonstration center - Medicinal chemistry
(rabbit, dog, guinea pig)
POlHL-17382-05 0003 Chemical mediators of acute
pulmonary disorders - Chemical mediators relevant to
allergic reactions (human, guinea pigs)
ROlHL-17921-04 Peroxy radicals to prostaglandins in
vessels and lung
ROlHL-18027-03 New vasoactive factors and their role in
hypertension (human, dogs, rats)
** ROlHL-18118-04 Total synthesis of cardiac aglycones
ROlHL-18226-04 Mechanism of oxygen supply to tissue
(human, animals)
ROlHL-18253-03 Structure of the palytoxins
** POlHL-18577-03 0005 Lipoproteins-Cell surface
interactions - Chemical synthesis of apolipoproteins and
apoliprotein fragments
** ROlHL-18679-04 Synthetic protease inhibitors
(contd)
I
•Excludes routine methodotogy OR covers only general projects which preclude
~OiiMt«d signttKintly to (bovt subject.
indexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant raimber
-mMwt^mt^mjliiMt.
Synlhtsli ol mol*cul«s lor myocatdld
OlloxInipMlllc tntllMdy in human
Biochemistiy of prothrombin quick
Active site studies on blood proteases
Inhibitors of cholesterol biosynthesis
CHE
•• ROIHI 1912/03
im<iln| (fits)
M POIHL 192S903
therapy
*• POIHI 192S9 03 0001 Di|o>in specific antibody in human
thtrapy Ptimary structure of monoclonal antibodies
(rabbits)
** POIHL 19?b9 03 0002 Di|oain specific antibody in human
therapy Chemical semi synthesis ol ditoxin specific
antibody (rabbits)
** POIHI 192!i903 0003 Oigoxin specific antibody In human
therapy Synthesis of dogoiin specific antibody in
continuous cell culture (human, sheep)
** POIHL 19259 03 0004 Oigoxin specific antibody m human
therapy Digitalis specific antibodies pharmacological
studies (human, dogs, sheep)
ROIHL 19374 03 Pharmacology ol kinins in cardiovascular
disease (rats, rabbits)
ROIHL 1941903 Cellular interactions v>ith foreign
materials (mammals)
ROIHL 19SW 03 Synthesis of inhibitors tor the study ol
renal renin (dogs, monkeys)
POIHL 19717 02 0005 Response of the lung to iniury
Studies on proteolysis and lung disease (human, animals)
ROIHL 1979503 Synthesis of anaphylatoxic and
leucotactic peptides (human)
ROIHL 20161 02 Role of gamma carboxyglutamic acid in
blood coagulation (human, cattle)
ROIHL 2022003 Anaphylatoxins as inflammatory and
chemotactic agents (guinea pig, rabbit, human)
POlHL-20993-02 0008 Population dynamics of arterial
cells in atherogenesis - Angiotoxicity of cholesterol
oxidation in atherogenesis (rabbits)
ROIHL 20996 02 Structural and reactivity of iron and
cobalt complexes
** ROIHL'21769'01 Blood compatible benzamidine containing
polymers
ROlHL-2187401 SRS-A-lts biosynthesis and action
POIHL-22163-01 9001 Surface thrombogenesis-
Mechanisms and prevention Polymers for studing blood-
material interactions core
** ROlHL-22252-01 Synthesis of labeled hemes for protein
NMR studies
ROlHL-2247101
(human)
ROlHL-2253001
(human)
** ROlHL-22532-01
(rats. mice, yeast)
ROlHL-22555-01 Structure and function of platelet
activating factor (rabbits, human)
R01HL-23120-01 Chelating agents as blood substitutes
*• N01HV-42984-05 Interactions of modified biopolymers y»ith
blood (humans, rats)
*• NOlHV-7294301 Prostaglandin and kallikrein kinin system
antagonists
** NOlHV-7294402 Prostaglandin and kallikrein kinin
antagonists
** NOlHV-72945-03 Develop prostaglandin synthesis and
receptor antagonists
*• NOlHV-7294602 Development of kallikrein-Kinin system
antagonists
CHEMICAL TRANSFER, ELECTRON TRANSPORT
POlHL-06312-17 0034 Surgical cardiology ■ Metabolic
factors in cardiac function-Creatine phosphate depletion
(animals)
POlHL-07896-15 0049 Environmental biomedical research
program • Effects of hyperbaric oxygen and pressure on
cerebral enzymes (rats)
** P01HL1215711 0051 Functions and mechanisms of cell
membrane ion transport - Electron transport in the red cell
membrane (human, guinea pigs)
R0IHL12526-09 Raman spectra of heme proteins and
related molecules
** ROlHL-12576-10 Bioenergetics apparatus in heart
mitochondria
ROlHL-13399-16 Heme protein structure and function
(human, horse, plants, bacteria)
** ROlHL-13619-09 Microsomal electron transport in liver
and heart (human, mammals)
ROlHL-13652-08 Metal sites in metalloproteins
(mushroom)
** R01HL1446108 Cardiac metabolism in heart failure
(rats)
P50HL-15061-07 0012 Response of lung to injury ■
Hyperbaric oxygen, carbon monoxide, and ozone or peroxide
toxicity (rats)
P01HL15835-06 0013 Study of muscles related to heart
disease - Cardiac bioenergetics (rats)
ROIHL- 15980-06 Reactions of hemeproteins and oxygen
(cattle)
** ROlHL-16087-05 Structural and dynamic study of model
heme complexes (yeast)
POlHL-16251-06 0008 Membrane-bound enzymes in heart
and other tissues - Iron-sulfur centers and phospholipids
modulation of succinate dehydrogenase
ROlHL-16686-04 Properties of cytochrome oxidase (cattle.
bacteria)
** ROlHL-1 7559-03 Structural elucidation of heart
cytochrome-C oxidase
ROlHl-17736-04 Metabolic change during cardiac
ischemia (rats, dogs)
1SI
Kinetic studies ul hemerythrin reactions
Heart adanyl cyclase complex (beef
Spectroscopic studies of respiratory
Picosecond laser studies of heme
Unsaturated latty acid biosynthesis In
ROIHI l/8?8 04
(marine wormi)
ROIHL 182/2 03
heart)
" POIHL 18/08 03 0003 Oxygen, energy and conlraclilily in
cardiac tissue Structural lunctional studies on cytochrome
c oxidase
ROIHL 1937803 Relation of mitochondrial changes to
cardiac failure (dogs, rats)
ROIHI 19392 03
metalloproteins
ROIHL 1948803
proteins
ROIHL 1993602
the aorta (rats)
ROIHL 20544 02 Integrated regulation of myocardial
energy metabolism (rats, guinea pigs)
** ROIHL 20658 01 Myocardial energy transport Creative
kinase (human, cattle, dog)
** ROIHI 2205001 Organization ol succinic oxidase in heart
ROIHL 2246101 Cardiac tropomyosin and tropomyosin
action interactions (rabbit)
ROIHL 22821 01 A routine screening analysis for
myoglobinemia
•* ROlHL-22981-17 Membrane associated functions in
microorganisms (bacteria, protozoa)
CHEMICAL TRANSFER, HYDROGEN TRANSPORT
SEE ALSO BIOLOGICAL TRANSPORT, ACTIVE TRANSPORT, ION
PUMPS, HYDROGEN PUMP
P01HL06285-18 0198 Cardiovascular-respiratory
physiology and biochemistry Renal tubular secretion of
hydrogen ion (animals)
POIHL-0628518 0211 Cardiovascular-respiratory
physiology and biochemistry Purple membrane of
Halobacteria
POIHL 11351 12 0024 Cellular and molecular
mechanisms of myocardial function - Steady state and
transient kinetics of frog myosin, SI. and ATPasc
** ROIHL 14483-08 Energy conservation in heart
mitochondria (cattle, E coli, human)
** POlHL-19737 02 0008 Cellular and molecular aspects of
respiratory physiology - Kinetics of movement of acid
metabolites from cell to capillary blood (dogs)
POlHL-19737-02 0011 Cellular and molecular aspects of
respiratory physiology - Chemical and metabolic factors on
peripheral chemoreceptor activity (cats)
ROlHL-201 53-02 Intracellular pH and myocardial
electropharmacology (dogs, guinea pigs)
CHEMICALS (GENERAL), ELEMENTS, TRACE
ELEMENTS
SEE ALSO NUTRITION. DIETARY CONSTITUENTS. DIETARY
TRACE ELEMENTS AND MINERALS
POlHL-08974-14 0005 Natural and experimental
atherosclerosis - Atherosclerosis, coronary heart disease
and sudden death (human)
ROlHL-13619-09 Microsomal electron transport in liver
and heart (human, mammals)
ROlHL-14131-18 Abnormal hemoglobin syndromes
(human)
** P60HL16008-06 0015 Wayne State University
comprehensive sickle cell center - Trace elements in sickle
cell disease (human)
** ROlHL-22603-01 Trace metals, vascular activity and
hypertension (rats)
CHEMICALS (GENERAL), MINERALS (GENERAL)
SEE ALSO CALCIUM (MINERAL) BALANCE (METABOLISM)
SEE ALSO SILICATES
ROlHL-02942-22 Biochemistry of cardiovascular connective
tissue (human, cattle, primates)
R01HL17543-03 0002 Magnetic tracers for diagnosis of
lung disease • Magnetite as an index of asbestos exposure
(human)
CHEMICALS (GENERAL), ORGANIC
COMPOUNDS (GENERAL)
** ROlHL-02835-21 Renal transport carrier for organic
compounds (dogs, rats)
R23HL-19605-01 Lipid requirement of the lung mono-
oxygenase system (rabbits)
ROlHL-22035-01 Molecular modification of heparin by
chemical means (sheep)
CHEMISTRY (GENERAL)*
SEE ALSO BIOCHEMISTRY (GENERAL)*
SEE ALSO BIOPHYSICAL CHEMISTRY (GENERAL)*
SEE ALSO HISTOCHEMISTRY AND CYTOCHEMISTRY
(GENERAL)*
SEE ALSO IMMUNOCHEMISTRY
SEE ALSO MEDICINAL CHEMISTRY STUDY SECTION
SEE ALSO MICROBIAL CHEMISTRY STUDY SECTION
SEE ALSO MOLECUUR BIOLOGY
SEE ALSO NEUROCHEMISTRY
SEE ALSO PATHOBIOLOGICAL CHEMISTRY STUDY SECTION
SEE ALSO PHOTOCHEMISTRY
SEE ALSO PHYSIOLOGICAL CHEMISTRY STUDY SECTION
** POlHL-20993-02 0012 Population dynamics of arterial
cells in atherogenesis ■ Chemistry laboratory -Core
CHEMISTRY, ANALYTICAL
SEE ALSO INDICATORS AND REAGENTS
•Excludes routine methodokigy OR covers only general projects which preclude indexing
**0nefited significantly to above subject.
at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
CHE
POIHI 09011 I'l OOO'i A rceiich and rtuuro pragiam
In blood Characleri/ation ol hepalilii B antigan and Iht
cause ol serum hep«tili> (human)
" RUIHl IIII9 1/ Ammo acid analy/er lor biochtmical
re\earch
ROIHI 14938 06 Contractile prolaint ol heart muxle
(dogs, rabbits)
P50H1 15062 0/ 0021 Study ol lipoprotelni, artiiy wall.
and atherosclerosis Core laboratories
ROIHL 15679 06 Heart and smooth muscle contractile
prolein (swine, cattle, rabbits, chickens)
ROIHL 15892 05 Inhibltori of prolainiMt (human, cattle,
swine)
ROIHL 18554 03 Taurine metabolism in mammalian heart
(rodents, cattle, swine)
ROIHL 2054/02 Glycoproteins in pulmonary alveolar
proteinosis (human)
ROIHL 22039 02 Ion transport in cardiac muscle (dogt,
rodents, cattle)
NOIHR 72921 01 Cystic fibrosis factor identification and
quantification (human)
*• NOIHR 72922 01 Cystic fribrosis factor identicafion and
quantification (human)
CHEMISTRY, ANALYTICAL METHODS*
SEE ALSO ELECTRODES. ENZYME*
SEE ALSO RESPIRATORY GAS ANALYZERS*
** POIHL 14414 07 9001 Environmental influences on
cardiorespiratory and cellular functions Laboratory core
facility
ROIHL 21303 02 Collagen synthesis by cultured human
vascular cells
ROIHL 21763-09 Heparin and heparan sulfate Structure
and activity (beef, hog)
** ROIHL 22355-01 Purification, structure and function of
factor VIII (human)
CHEMISTRY, ANALYTICAL METHODS,
CRYSTALLOGRAPHY*
SEE ALSO CHEMICAL REACTIONS, SUBSTITUTION,
ISOMORPHOUS
ROlHL-08299-16 Molecular biology of hemerythrin and
hemocyanin (invertebrates)
ROlHL-12395-10 X-ray study of oxygen-carrying cobalt
complexes
P60HL-15158-07 0014 Comprehensive sickle cell center •
Mechanism of sickling in human and deer hemoglobins
ROIHL- 15284-06 Hemoglobin and myoglobin kinetic
studies (human, animals)
ROlHL-15378-06 Ullrastructure of antihypertensive
prostaglandins
R01HL-15627-06 X-ray and chemical studies of
metalloporphyrins
NOlHV-32919-12 Material development and testing
heparinization processes
CHEMISTRY, ANALYTICAL METHODS,
SPECTROMETRY*
SEE ALSO ELECTRONIC SPECTRA
SEE ALSO OPTICS. DICHROISM CIRCUUR*
SEE ALSO OPTICS. INTERFEROMETRY*
SEE ALSO PHYSICAL SEPARATION. ULTRACENTRIFUGATION.
ANALYTICAL*
POlHL-21016-02 0014 Sickle cell anemia and other
hemoglobinopathies - Human hemoglobin mutants with
abnormal oxygen binding
CHEMISTRY, ANALYTICAL METHODS,
SPECTROMETRY, ATOMIC ABSORPTION*
** POlHL-20592-02 0014 Cell biology of cardiac and
skeletal muscle - Core laboratory
CHEMISTRY, ANALYTICAL METHODS,
SPECTROMETRY, ELECTRON PROBE*
** ROlHL-02493-22 Kidney function in experimental heart
failure (dogs, rats)
POlHL-06285-18 0173 Cardiovascular-respiratory
physiology and biochemistry - Skeletal and cardiac muscle
function
** POlHL-11351-12 0018 Cellular and molecular
mechanisms of myocardial function - Quantitative
localization of electrolytes in cardiac tissue
** POlHL-14388-07 9003 Regulation of the circulation in
pathological states - Electron probe projects
** P01HL-16833-04 0008 Hemoglobin and red cell system in
hemoglobinopathies ■ Membrane associated phenomena in
SS disease
ROlHL-18798-04 0002 Nervous and ionic factors in
sudden cardiac death - Electron microprobe. ullrastructure
analysis of ischemic myocardium (dog. rabbit)
** ROlHL-22281-01 Microprobe analysis and metabolite
levels of ischemic mycardium (dogs)
CHEMISTRY, ANALYTICAL METHODS,
SPECTROMETRY, ESR*
R01HL-12760-09 Surface studies of membrane lipids and
proteins
ROlHL-13399-16 Heme protein structure and function
(human, horse, plants, bacteria)
** P60HL-1 5168-07 0009 Comprehensive sickle cell disease
center - Spin-label study of sickling (human)
(contd)
CHE
P60HL-17269-04 0046 National heart and blood vessel
research and demonstration center ■ Nuclear magnetic
resonance laboratory
ROlHL-18551-03 Spectrin, actin. lipid and red cell
membrane structure
** R01HL19065-02 Molecular oxygen in biological fluids
** POlHL-21016-02 0015 Sickle cell anemia and other
hemoglobinopathies - EPR study ot NO derivatives of Hb
Beth Israel (human)
CHEMISTRY, ANALYTICAL METHODS,
SPECTROMETRY, FLUORESCENCE*
ROlHL-13694-08 Capillary basement membrane in
cardiovascular disease (human, rats)
** R01HL18163-04 Red cell membrane effects due to
oxidizing agents
CHEMISTRY, ANALYTICAL METHODS,
SPECTROMETRY, INFRARED*
** POlHL-08214-15 0010 Chemical and biological properties
ot lipids ■ Infrared spectroscopy of lipids
NOlHR-72920-01 Identity and quantify cystic fibrosis
factors (human)
CHEMISTRY, ANALYTICAL METHODS,
SPECTROMETRY, LASER*
** ROlHL-20192-02 Ciliary activity of the lung studied by
laser scattering
CHEMISTRY, ANALYTICAL METHODS,
SPECTROMETRY, MASS*
POlHL-07896-15 0036 Environmental biomedical research
program ■ Respiratory heat loss in deep diving (infants,
dogs)
POlHL-0821415 0006 Chemical and biological properties
of lipids - Analysis and properties of lipids
** POlHL-08214-15 0047 Chemical and biological properties
of lipids ■ High resolution liquid chromatography for the
analysis of biological substances
** P60HL-17269-04 0016 National heart and blood vessel
research and demonstration center • New analytical
methodology for atherosclerosis studies
•* POlHL-19737-02 0012 Cellular and molecular aspects of
respiratory physiology - Mass spectrometer facility
** ROlHL-20607-02 Tissue analysis by mass spectrometer
(dogs)
CHEMISTRY, ANALYTICAL METHODS,
SPECTROMETRY, NMR*
** NOlHI-02216-10 To develop biological flow NMR concept
(human, mammals non human)
** POlHL-08214-15 0040 Chemical and biological properties
of lipids - Nuclear magnetic resonance studies of lipids
POlHL-11310-12 0101 Mechanisms of cardiovascular
disease - Molecular pathogenesis of vascular disease
R01HL12528-10 NMR relaxation of liquid ciystal systems
R01HL14680-07 Specific enrichment of myoglobins for
carbon 13 NMR (catacea)
ROlHL-16746-04 Design of ion-selective molecules
** P60HL17269-04 0046 National heart and blood vessel
research and demonstration center - Nuclear magnetic
resonance laboratory
ROlHL-18834-04 Metal-dependent complex formation in
blood coagulation (human, cattle)
" ROlHL-19065-02 Molecular oxygen in biological fluids
•* ROlHL-19481-03 High-field NMR studies of respiratory
proteins (human, horse, fish, microbes)
** ROlHL-2 1706-02 Nuclear magnetic resonance and
myocardial ischemia (rats)
** ROlHL-22080-01 Phosphorus NMR studies on cardiac
tissue (rats, rabbits)
CHEMISTRY, ANALYTICAL METHODS,
SPECTROMETRY, PHOTOEIECTRON*
ROIHLI 151 1-10 Structure of ferritin and its role in iron
metabolism (horse, rats, human)
CHEMISTRY, ANALYTICAL METHODS,
SPECTROMETRY, RAMAN*
ROlHL-12526-09 Raman spectra of heme proteins and
related molecules
CHEMISTRY, ANALYTICAL METHODS,
SPECTROMETRY, X-RAY*
ROlHL-21371-02 Energy loss microanalysis of myocardial
cations
CHEMISTRY, ANALYTICAL METHODS,
SPECTROPHOTOFIUOROMETRY*
ROlHL-22402-01 Heparinbiophysical. chemical and
biological aspects (mice, human)
CHEMISTRY, ANALYTICAL METHODS,
TEMPERATURE JUMP*
POlHL-1 1307-12 0003 Biophysical studies in pediatric
cardiology ■ Cellular biophysics (animals)
POlHL-1 1307-12 9002 Biophysical studies in pediatric
cardiology - Biomedical engineering
•* ROlHL-19848-02 Contractile activation by rapid
temperature jumps (frogs)
152
CHEMISTRY, ANALYTICAL METHODS, X-RAY
STRUCTURE ANALYSIS*
ROlHL-03424-21 Formation and properties of prothrombin
derivatives (human, animals)
P01HL06285-18 0212 Cardiovascular-respiratory
physiology and biochemistry - Membrane structure and
function-Gap junction (bovine)
POlHL-06285-18 0213 Cardiovascular-respiratory
physiology and biochemistry - Membrane structure and
function -Gas vacuole membrane (Halobacterium)
** P50HL-15092-07 0001 Immune and fibrotic response to
occupational environments - X-ray diffraction study -Dust
exposure in asbestos cement products manufacturing
P60HL-15158-07 0014 Comprehensive sickle cell center -
Mechanism of sickling in human and deer hemoglobins
** POlHL-174 19-04 0007 Studies on mechanisms of
hemostasis - Structural analysis of ordered forms of
fibrinogen (human, cattle)
ROlHL-18309-04 Oxygen transport-Hemoglobins with
modified hemes (horse)
ROlHL-18798-04 0002 Nervous and ionic factors in
sudden cardiac death - Electron microprobe. ultrastructure
analysis of ischemic myocardium (dog. rabbit)
CHEMISTRY, CLINICAL
** P01HL08974-14 9001 Natural and experimental
atherosclerosis - Core-Lipid chemistry laboratory
P01HL12373-10 0018 Cardiopulmonary physiology and
pathophysiology - Biochemistry laboratory
** P50HL-14164-07 0040 A/S SCOR -Comparative and
experimental atherosclerosis - Core angiochemistry
laboratory
** P50HL-183 18-03 0003 Pathogenesis and complications of
hypertension - Core biochemical laboratory
ROlHL-1906502 Molecular oxygen in biological fluids
** ROlHL-20500-02 Diabetic human brain microvascular
basement membrane (human)
ROIHL 22265-02 Isozymes of heart glutamate aspartate
transaminase (swine, ducks)
NOIHR 72920-01 Identify and quantify cystic fibrosis
factors (human)
CHEMISTRY, CLINICAL, BLOOD
P01HL06285-18 0164 Cardiovascular-respiratory
physiology and biochemistry - CPK MB isoenzyme
concentration to quantify infarct size (human, animals)
POlHL-08805-15 0006 Regulation of ventilation and
pulmonary circulation - Adaptation of lungfish-Estivation
** ROlHL-10160-13 Origins of atherosclerosis (human)
•* ROlHL-12085-10 Lipoproteincarbohydrate metabolism
(human, rats)
** P50HL-14141-05 0008 SCOR for atherosclerosis in
childhood • Core laboratory
P50HL14147-08 0017 Specialized center of research in
thrombosis • Core coagulation laboratory (human)
P50HL-14159-08 0022 Specialized center of research in
hypertension - Core laboratory
P50HL-141 64-07 0034 A/S SCOR -Comparative and
experimental atherosclerosis - Core lipid analytic laboratory
P50HL-14197-07 0007 Support for center of research on
arteriosclerosis • Metabolic defects in familial
hyperlipoproteinemias (human)
P50HL-14230-07 9001 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Core lipid laboratory
P50HL14236-05 0012 Prevention of premature
arteriosclerosis - Automated lipid analysis
P50HL-14237-07 0007 Support for arteriosclerosis center
- Core laboratories
P50HL-15062-07 0013 Study of lipoproteins, artery wall,
and atherosclerosis - Radioimmunoassay of apolipoproteins
(human, monkeys)
P50HL-15062-07 0021 Study of lipoproteins, artery wall,
and atherosclerosis - Core laboratories
** P60HL-15158-07 0008 Comprehensive sickle cell center -
Core laboratory of the center
P60HL-15169-05 0019 Support for center for sickle cell
disease - Central screening and reference laboratory
P60HL-1517005 0002 Support for center for sickle cell
anemia - Adult services -Testing programs
*♦ ROlHL-15308-07 Assays for peptides of lipoproteins
(human) .
P60HL-1 5999-05 0004 Miami comprehensive sickle cell
center - Education, screening and counseling
** P60HL-16005-05 9001 Comprehensive sickle cell center ■
Core laboratory and counseling (human)
ROlHL-16580-04 Mathematical models for studying sickle-
cell disease
P50HL17646-04 0005 Study ot ischemic heart disease -
Biochemical markers and mediators of myocardial ischemic
injury
P50HL-1 7646-04 0006 Study of ischemic heart disease ■
Mathematical models for predicting infarct size using CPK
and other markers
** P50HL-17665-04 0008 Study of ischemic heart disease -
Core laboratory-CPK isoenzyme measurement and
myocardial necrosis evaluation
** P50HL17667-04 0040 Study of ischemic heart disease ■
Core biochemistry-Cardiac metabolism (human)
P50HL-17667-04 0043 Study of ischemic heart disease -
Quantitation of myocardial infarct size by serial enzyme
measurements (human)
P50HL-17670-04 0017 Study of ischemic heart disease -
Core enzymology laboratory (human)
CHE
P50HL-17682-04 0010 Study of ischemic heart disease -
Core clinical enzyme laboratory (human, mice. dogs, rats)
R01HL1816304 Red cell membrane effects due to
oxidizing agents
P50HL-18318-03 0003 Pathogenesis and complications ot
hypertension - Core biochemical laboratory
P50HL-18323-04 0033 SCOR hypertension center - Core
laboratory-Renin. aldosterone and bradykinin methodology
' ROlHL-18561-03 Radioimmunoassay of angiotensinogen
(human) . .
' ROlHL-18567-03 A routine diagnostic test for minimal
heart damage (human, rat)
' P50HL- 19 157-02 0008 Studies in cystic fibrosis and
bronchiolitis ■ Serum proteins in cystic fibrosis (human)
ROlHL-19223-03 Control of cholesterogenesis in leukocytes
and liver (rats, human)
P50HL-19362-02 0013 A/S SCOR-Atherosclerosis in
nonhuman primates - Core laboratory-Lipid biochemistry
(baboons)
* ROlHL-19973-01 Noninvasive sickled cell monitor
development (human)
ROlHL-19974-02 Psychologic-behavioral influences on
heart pathology (rats)
* ROlHL-20418-03 Serum cholesterol binding reserve in
diabetes (human)
ROlHL-20539-03 Blood glucose, hemoglobin Ale, and
diabetic vascular disease (human)
ROlHL-20712-02 Characterization of the 8 proteins of
serum lipoproteins (human)
ROlHL-20807-02 Detection of familial hypercholesterolemia
(human)
ROlHL-2095402 Hyperlipoproteinemia (rats, human)
P50HL-21006-02 0001 Specialized center of research in
arteriosclerosis • Clinic and core program
P50HL-21006-02 0002 Specialized center of research in
arteriosclerosis - Turnover and metabolism of cholesterol in
man
ROlHL-21461-01
hemoproteins
ROlHL-21791-01
Heme group protein interactions in
Precipitation of proteins with poly
(ethylene glycol) (human)
ROlHL-22265-02 Isozymes of heart glutamate aspartate
transaminase (swine, ducks)
** ROlHL-22402-01 Heparinbiophysical, chemical and
biological aspects (mice, human)
** ROlHL-22474-01 Cholesterol metabolism and
atherosclerosis (rats, human, rabbits)
** ROlHL-22567-01 Validation of a cholesterol absorption
method in man
ROlHL-22607-01 Role of apolipoprotein E in lipoprotein
metabolism (human)
** ROlHL-22618-01 Role of apolipoproteins In
hypertriglyceridemia (human)
** ROlHL-22847-01 Test for adherence to diets rich in
linoleic acid
ROlHL-22859-01 Effect of carbon monoxide on the
developing heart (rats)
NOlHV-32933-07 Hypertension detection and follow-up
program central laboratory (human)
CHEMISTRY, CLINICAL, FECES ANALYSIS*
P50HL-19362-02 0013 A/S SCOR-Atherosclerosis in
nonhuman primates - Core laboratory-Lipid biochemistry
(baboons)
CHEMISTRY, CLINICAL, URINE CHEMICAL
ANALYSIS
POlHL-06835-17 0050 Cardiovascular disease - 18-
Hydroxylase block in the 17 alpha-hydroxylase deficiency
syndrome (human)
P50HL-14159-08 0022 Specialized center of research in
hypertension - Core laboratory
ROlHL-16320-05 Vasoactive peptides which stimulate
smooth muscles (rats, human)
P50HL-183 18-03 0003 Pathogenesis and complications of
hypertension ■ Core biochemical laboratory
P50HL-18323-04 0033 SCOR hypertension center - Core
laboratory-Renin, aldosterone and bradykinin methodology
CHEMISTRY, ELECTROCHEMISTRY
SEE ALSO ELECTRICAL MEASUREMENTS, POLAROGRAPHY*
SEE ALSO ELECTRICAL MEASUREMENTS, POTENTIOMETRY*
SEE ALSO ELECTRODES, ENZYME*
SEE ALSO MOLECULAR POURITY
SEE ALSO PHYSICAL SEPARATION, ELECTROFOCUSING*
SEE ALSO PHYSICAL SEPARATION, ELECTROPHORESIS*
P50HL-14147-08 0013 Specialized center of research in
thrombosis - Mathematical models of blood coagulation
kinetics
** P50HL-14147-08 0014 Specialized center of research in
thrombosis - Theoretical models for electrostatic effects in
blood clot formation
•* P50HL-14147-08 0015 Specialized center of research in
thrombosis - Charge related properties of phospholipid
surfaces in monolayers and vesicles
** POIHL- 14388-07 0168 Regulation of the circulation in
pathological states ■ Ionic basis of depolarization (rats,
tissue culture)
ROlHL-15640-06 Thermodynamic studies on model oxygen
carriers
POlHL-20592-02 0003 Cell biology of cardiac and
skeletal muscle - Cellular magnesium and anion activities
in ion-specific microelectrodes (frogs)
(cofitd)
•Excludes routine methodokjgy OR covers only general projects which preclude
"Oriented significantly to above subject.
indexing at the specific level.
M Grant has subprajects describing specific research aspects.
See Appendix foe investigator's name and grant number
CHf
183
CMI
ROIHl ?U36 O; Ion ictivKlts and Kiniport In cinllic
muscle oils (shvep)
ROIHL 2IU9 01 Volumt regulation Role ot the mrmb(iint)
potential (amphiuma)
ROIHI 228?l 01 A routine screening analysis tor
myoglobinemia
ROIHl 23183 01 Voltage dependent conductance in
membranes
NOIHV S290; 04 Interactions ol platelets witli collagens
(tiuman, mammals)
CHEMISTRY, QUANTUM (GENERAL)
SLE ALSO ELfCIRONIC SPECTRA
ROIHL 19488 03 Picosecond laser studies ol heme-
proteins
R01HL2148301
ol hemoglobin
ROIHL 2339201
Electronic, thermodynamic and kinetics
Membrane binding and transport ol
calcium and potassium lonophores
CHEMISTRY, STOICHIOMETRY
P0IHL0e664 i; 0040 Cardiopulmonary tunction in
remediable vascular disease The coupling ot ion transport
to metabolism (toads)
ROIHL 11822 10 Biophysical studies of macromolecular
interactions (microorganism, human)
POIHL 1326207 0012 Arterial wall in atherosclerosis
Characterization ot connective tissue components (animals)
P50HL 14164 07 0035 A/S SCOR Comparative and
experimental atherosclerosis Lipid metabolism -Interaction
with arterial metabolism (monkey, pigeon)
P50HL 1421708 0058 Specialized center of research In
thrombosis - Mechanisms of induction and Inhibition of
platelet reaction (human, pig)
P50HL 1421708 0062 Specialized center of research in
thrombosis Coagulation section -Factor VIII and Factor XII
(human, cattle)
P50HL1423605 0008 Prevention of premature
arteriosclerosis Lipoproteins of cell membranes (human)
POlHL-1438807 0175 Regulation of the circulation In
pathological states Functional studies of selected proteins
from cardiac muscle
ROlHL-15648-06 Lipid metabolism -Transport by lateral
diffusion (human, rabbit, cattle)
ROlHL-15692 07 Force and speed In skeletal and cardiac
muscle
P01HL16251-06 0008 Membrane-bound enzymes in heart
and other tissues Iron-sulfur centers and phospholipids
modulation of succinate dehydrogenase
ROlHL-16318-21 Biochemistry and pharmacology of Na K
transport
ROlHL-1647405
membranes)
ROlHL-16611-04
pigs, rats)
ROlHL-16746-04
ROlHL-19676-02
Antibiotic-ion Interactions (model
Digitalis-receptor of the heart (guinea
Design of Ion-selective molecules
Physico-chemical interactions In
pulmonary surfactant
R01HL-20711-01 Structure-function relationships In red
cell NA-K pumps (goats)
ROlHL-21329-02 Beta-receptor regulation and cardiac
sites of drug action (cat. guinea pig. rat)
R23HL-21663-01 Regulation of collagen biosynthesis
(chick, embryo)
ROIHL-22050-01 Organization of succinic oxidase in heart
ROlHL-22239-01 The molecular basis of electrical
excitability (chick embryos, rats)
ROlHL-22550-02 Genetic cardiomyopathies In salamanders
and hamsters
ROlHL-22570-01 Interactions of sterols In biological
systems (human)
POlHL-22619-01 0011 Cellular mechanisms of heart
failure - Reaction of lipoproteins and apolipoproteins with
lipoprotein lipase (cattle)
ROlHL-23249-01 Actln-myosin Interaction In pulmonary
smooth muscle (cattle)
CHEMISTRY, THERMODYNAMICS (GENERAL)
POlHL-06285-18 0195 Cardiovascular-respiratory
physiology and biochemistry - Thyroid thermogenesis and
sodium transport (rats)
POlHL-06285-18 0210 Cardiovascular-respiratory
physiology and biochemistry - Physlcochemlcal and
enzymatic studies of lung surfactant (Halobacterium)
P01HL-06314-17 0053 Immunologic mechanisms In
cardiovascular disease Cellular functions controlled by
cyclic GMP (human, mice, guinea pigs)
ROlHL-07451-16 Hemoglobin S gelation and hemoglobin
allostery (human)
P01HL07896-15 0009 Environmental biomedical research
program - Decompression sickness and computation of safe
diving tables (human, animals)
ROlHL-10036-13 Biology of red cell antigen-antibody
reaction (human)
POlHL-11351-12 0004 Cellular and molecular
mechanisms of myocardial tunction - Molecular
mechanisms of contractile function and differentiation
(animals)
POlHL-1 1351-12 0006 Cellular and molecular
mechanisms of myocardial function - Molecular physiology
and energetics of muscle (frogs)
'Excludes routine methodokigy OR covers only general projects whicti preclude indexing
"OnenteO signdicanlly to above subject.
POIHL II35I 17 0021 Cellular and inolMUlar
mechanisms ol myocardial function Muiclt MMrfttlet
(frogs)
POIHL 11351 12 0022 Cellular and molecular
mechanisms ol myocardial lunction Energetic sequalat Ol
shortening Myolhermol and biochemical (frogs)
POIHL 11351 12 0023 Cellulai and molecular
mochanisms ol myocardial lunction Energetics ol
mammalian muscle (rats)
POIHL 11J5I 12 0024 Cellular and molecular
mechanisms ol myocaidial lunction Steady state and
transient kinetics of frog myosin, S 1. and AlPase
POIHL 12157 11 0038 Functions and mechanisms of cell
membrane ion transport Mechanisms and interactions ol
gases and ions with bilayer membranes (human)
ROIHL 12256 15 Polymerization of sickle cell hemoglobin
(human)
ROIHL 12528 10 NMR relaxation of liquid crystal systems
ROIHL 12974 10 Tracer kinetics, Hows and masses in
body organs (human, dogs)
ROIHL 1303508 Heart mitochondrial malate
dehydrogenase regulation
ROIHL 13157 09 Molecular oxygen carriers Synthesis.
structure, bonding
ROIHL 1316407 Interaction of the alpha and beta chains
ot human hemoglobin
ROIHL 15640-06 Thermodynamic studies on model oxygen
carriers
ROIHL 164 74 05 Antibiotic Ion Interactions (model
membranes)
POIHL 16683 04 0002 Function and growth of cardiac
and skeletal muscle Myosin, actin, ATP, interaction in
solution
ROlHL-16711 05 R6C and endothelial membrane material
characteristics (human)
POlHL-16833 04 0002 Hemoglobin and red cell system in
hemoglobinopathies - Polymerization and gel formation in
solutions of hemoglobin A and S (human)
POlHL-16833-04 0006 Hemoglobin and red cell system In
hemoglobinopathies Role of water In function of
hemoglobin and myoglobin (human)
ROlHL-17559 03 Structural elucidation of heart
cytochrome-C oxidase
ROlHL-17592-03 Activation and contraction heat in
enlarged hearts (rabbits)
ROlHL-17878-04 Structural studies of the human
erythrocyte membrane
ROlHL-18048-04 Dynamics of artificial and biological
membranes (human)
ROlHL-18441-03 Guidelines for polymers acting as elastln
substitutes
POlHL-18577-03 0003 Lipoproteins-Cell surface
Interactions Mechanism of lipid exchange In lipoproteins
and cell membranes
ROlHL-18623-12 Physical chemistry of biologically active
lipids (bacteria, plant, cattle, human)
P01HL-18708-03 0003 Oxygen, energy and contractility in
cardiac tissue - Structural-functional studies on cytochrome
c oxidase
POlHL-18708-03 0005 Oxygen, energy and contractility in
cardiac tissue - Cytosollc calcium homeostasis and
bloenergetlcs of cardiac tissue (animals)
ROlHL-18933-03 Energy output and efficiency of left
ventricle (dog)
ROlHL-19459-03 Dynamics of atherogenesis and
lipoprotein formation (human, rabbit)
POlHL-20984-02 0002 Cellular mechanisms In cardiac
hypertrophy - Thermodynamic, fluorescence, chemical
modification of hypertrophled heart myosin
POlHL-210 16-02 0004 Sickle cell anemia and other
hemoglobinopathies - Kinetics of sickling
ROlHL-21461-01
hemoproteins
ROlHL-21483-01
Heme group protein Interactions in
Electronic, thermodynamic and kinetics
of hemoglobin
ROlHL-22325-01 Thermodynamics In respiratory protein
binding (human, trout)
ROlHL-22569-02 Intestinal secretion -Capillary and tissue
forces (dogs, cats)
ROlHL-22570-01 Interactions of sterols in biological
systems (human)
POlHL-226 19-01 0011 Cellular mechanisms of heart
failure - Reaction of lipoproteins and apolipoproteins with
lipoprotein lipase (cattle)
ROlHL-22682-01 Structure and function of high density
lipoprotein (human, rat)
CHEMORECEPTORS
SEE SENSE ORGANS, CHEMORECEPTORS
CHEMOTACTIC FACTORS (COMPLEMENT)
SEE IMMUNOLOGY. COMPLEMENT, CHEMOTACTIC FACTORS
CHEMOTACTIC FACTORS (LEUKOTAXIC FACTOR)
SEE HYPERSENSITIVITY. LYMPHOKINES, LEUKOTAXIC FACTOR
CHEMOTAXiS
SEE ENVIRONMENT. ORIENTATION. CHEMOTAXIS
CHEMOTHERAPY
SEE DRUGS, CHEMOTHERAPY
CHEMOTHERAPY, BLOOD DISORDERS
SEE BLOOD AND RE DISORDERS CHEMOTHERAPY
at the specific level.
M Grant has subproiects describing specific research aspects-
See Appendix for investigator's name and grant number
CHEMOTHERAPY, CANCER
Ml NIOI'IAMir lill MAI'Y (.ANCFR CHfMOTHfRAPY
CHEMOTHERAPY, CARDIOVASCULAR
DISORDERS
Ml l,AKI)IOVA',(,l)IAH l)l',0«l;l «■, I.MI Mlillll PAI'r
CHEMOTHERAPY, COMMUNICABLE DISEASES
Sfl COMMIJNICAHII DIM AM ', (.III MOKK KAPY
CHEMOTHERAPY, CONNECTIVE TISSUE
DISORDERS
SFf CONNfCIIVf TISSUE DISOROfRS CHEMOTHERAPY
CHEMOTHERAPY, ENDOCRINE DISORDERS
SFf fNDOCRINOIOCY. INDOCRINI OI'.OPIjIR',
CHfMOIHFRAPY
CHEMOTHERAPY, GASTROINTESTINAL
DISORDERS
SEE GASTROINTESTINAL DISORDERS CHEMOTHERAPY
CHEMOTHERAPY, HEART DISORDERS
SEE HEART DISORDERS CHEMOTHERAPY
CHEMOTHERAPY, IMMUNOLOGICAL DISORDERS
SEE IMMUNOPAfHOLOGY, CHEMOTHERAPY
CHEMOTHERAPY, KIDNEY DISORDERS
SEE KIDNEY DISORDERS CHEMOTHERAPY
CHEMOTHERAPY, LIVER DISORDERS
SEE LIVER DISORDERS CHEMOTHERAPY
CHEMOTHERAPY, MENTAL DISORDERS
SEE PSYCHOLOGY ABNORMAL, MENTAL DISORDERS
CHEMOTHERAPY
CHEMOTHERAPY, METABOLIC DISORDERS
SEE METABOLIC DISORDERS CHEMOTHERAPY
CHEMOTHERAPY, NERVOUS DISORDERS
SEE NERVOUS DISORDERS CHEMOTHERAPY
CHEMOTHERAPY, NEUROMOTOR DISORDERS
SEE NEUROMOTOR DISORDERS CHEMOTHERAPY
CHEMOTHERAPY, NUTRITIONAL DISORDERS
SEE NUTRITIONAL DISORDERS CHEMOTHERAPY
CHEMOTHERAPY, PREGNANCY DISORDERS
SEE PREGNANCY DISORDERS CHEMOTHERAPY
CHEMOTHERAPY, REPRODUCTIVE SYSTEM
DISORDERS
SEE REPRODUCTIVE SYSTEM DISORDERS CHEMOTHERAPY
CHEMOTHERAPY, RESPIRATORY DISORDERS
SEE RESPIRATORY DISORDERS CHEMOTHERAPY
CHENODEOXYCHOLIC ACID
SEE CHOLANATE SERIES, CHENODEOXYCHOLIC ACID
CHEST INJURIES
SEE INJURIES, CHEST
CHICK EMBRYO
SEE BIRDS, CHICK EMBRYO*
CHILD BEHAVIOR
SEE CHILD MENTAL DEVELOPMENT, CHILD BEHAVIOR
CHILD CARE PERSONNEL
SEE CHILD WELFARE, CHILD CARE PERSONNEL
CHILD DEVELOPMENT (NON-PSYCHOLOGICAL)
SEE ALSO CHILD MENTAL DEVELOPMENT
SEE ALSO EMBRYOLOGY (HUMAN) AND DEVELOPMENT STUDY
SECTION
P50HL-14136-07 0009 Pulmonary SCOR-Airways
obstructive diseases - Tuscon epidemiological study of
airways obstructive disease (human)
P50HL-14136-07 0017 Pulmonary SCOR-Airways
obstructive diseases Pediatric airv»ays obstructive disease
(human)
** P50HL-14141-05 0007 SCOR for atherosclerosis In
childhood - Relation of lipid valves to sexual maturation at
puberty (human)
** P50HL-14214-07 0013 Newborn lung center for hyaline
membrane disease - Developmental outcome of children
who had HMD as Infants
P60HL-15158-07 0004 Comprehensive sickle cell center ■
Expression of abnormal hemoglobin synthesis In the
neonate and young child
P60HL-15160-07 0009 Center for sickle cell disease -
Natural history of sickle cell disease (human)
ROlHL-15525-05 Respiratory mechanics in children
ROlHL-16329-04 Cardiac surgical effect on heart function
in Infants (human)
ROlHL-17993-04 0009 Ventricular dynamics from
surgically inserted markers - Cardiovascular visualization in
surgery of growing heart (dogs)
" P50HL-19171-02 0001 Pulmonary SCOR-Lung injury by
childhood Infections - Longitudinal study-Respiratory
Infections and lung growth In normal children
P50HL-19187-02 0007 Pediatric pulmonary SCOR-Hyaline
membrane disease - Follow-up study-Infants with hyaline
membrane disease (human)
(contd)
CHI
ROlHL-20124-02 Coronary risk factors (human)
NOlHR-72973-01 Health education and attitudes of family
toward asthmatic children
CHILD DEVELOPMENT, PUBERTY
** P50HL14141-05 0007 SCOR for atherosclerosis in
childhood - Relation of lipid valves to sexual maturation at
puberty (human)
ROlHL-18456-03 Cardiovascular follow-up of hypertensive
adolescents
CHILD GUIDANCE (SERVICES)
SEE CHILD MENTAL HEALTH (SERVICES)
CHILD HEALTH CARE (SERVICES)
SEE ALSO HOSPITALS, NURSERY
** P50HL14136-07 9006 Pulmonary SCOR-Airways
obstructive diseases - Pediatric lung function core
P50HL-142 14-07 0012 Newborn lung center for hyaline
membrane disease Pulmonary status of children who had
HMD as infants
P50HL-15103-07 0001 A/S SCOR-Early natural history of
arteriosclerosis - Clinical research-Bogalusa heart study
(children)
** P60HL15158-07 0012 Comprehensive sickle cell center -
Clinical services -Pediatric patients
P60HL-15158-07 0025 Comprehensive sickle cell center -
Cardiovascular evaluation of children with sickle cell
disease (human)
P60HL-15160-07 0017 Center for sickle cell disease -
Demonstration -Education, screening, counseling, patient
care
P60HL15162-07 0001 Comprehensive sickle cell center -
Core program -Patient care
P60HL15162-07 0010 Comprehensive sickle cell center -
Core program-Community outreach and education program
P60HL-15168-07 0002 Comprehensive sickle cell disease
center - Patient care
P60HL-15168-07 0010 Comprehensive sickle cell disease
center - Sickle cell center project (children)
** P60HL-15170-05 0006 Support for center for sickle cell
anemia - Pediatric services-Comprehensive clinic
** P60HL-15170-05 0007 Support for center for sickle cell
anemia • Pediatric services-Screening program
M P60HL-15996-06 Cincinnati comprehensive sickle cell
center
P60HL-15996-06 0003 Cincinnati comprehensive sickle
cell center - Prophylactic penicillin in treatment of sickle
cell anemia (human)
** P60HL-15996-06 0005 Cincinnati comprehensive sickle
cell center - Factors precipitating crises (human)
P60HL 1599606 0006 Cincinnati comprehensive sickle
cell center • Education
P60HL15996-06 0007 Cincinnati comprehensive sickle
cell center ■ Screening and counseling
** P60HL-15996-06 0008 Cincinnati comprehensive sickle
cell center - Patient care (children, adults)
P60HL-1 5999-05 0005 Miami comprehensive sickle cell
center - Sickle cell clinic
** P60HL-16008-06 0001 Wayne State University
comprehensive sickle cell center - Patient care system
(children, adults)
*• P50HL-19157-02 0002 Studies in cystic fibrosis and
bronchiolitis - Clinical core
M P50HL-19171-02 Pulmonary SCOR-Lung injury by
childhood infections
P50HL-19171-02 0001 Pulmonary SCOR-Lung injury by
childhood infections - Longitudinal study-Respiratory
infections and lung growth in normal children
P50HL-19171-02 0005 Pulmonary SCOR-Lung injury by
childhood infections - Chronic respiratory disease of
children in North Carolina
P50HL-19171-02 0011 Pulmonary SCOR-Lung injury by
childhood infections - Clinical support core
P50HL-19187-02 0007 Pediatric pulmonary SCOR-Hyaline
membrane disease - Follow-up study-Infants with hyaline
membrane disease (human)
** P50HL-19190-02 0002 Pulmonary SCOR-Pathophysiology,
management of IRDS ■ Core-Demonstration and
dissemination
ROlHL-20351-02 A self-calibrating in vivo blood gas
monitor (dogs, infants)
" P60HL-20985-01 0009 Northern California sickle cell
center - Patient services (children, adults)
ROlHL-22636-01 Newborn lung function during
mechanical ventilation (human)
** NOlHR-72972-01 Self-management for asthmatic children
CHILD MENTAL DEVELOPMENT
SEE ALSO INFORMATION-COMMUNICATION BEHAVIOR,
LANGUAGE DEVELOPMENT
SEE ALSO PSYCHOLOGY EDUCATIONAL (GENERAL)
** P50HL-14214-07 0013 Newborn lung center for hyaline
membrane disease - Developmental outcome of children
who had HMD as infants
P50HL-14218-07 0015 Pulmonary SCOR-Newborn lung
center - Long term follow-up of infants surviving RDS-
Neurological outcome (human)
P60HL- 15 160-07 0009 Center for sickle cell disease -
Natural history of sickle cell disease (human)
** P50HL-19185-02 0011 Pulmonary SCOR-Neonafal
respiratory distress syndromes - Complications and
sequelae of neonatal respiratory distress (human)
154
P50HL-19187-02 0007 Pediatric pulmonary SCOR-Hyaline
membrane disease - Follow-up study-Infants with hyaline
membrane disease (human)
CHILD MENTAL DEVELOPMENT, CHILD
BEHAVIOR
P60HL-15996-06 0004 Cincinnati comprehensive sickle
cell center - School adjustment of sickle cell patients
** NOlHR-72973-01 Health education and attitudes of family
toward asthmatic children
♦* NOlHR-72974-01 Self-management systems for asthmatic
children
CHILD MENTAL HEALTH (SERVICES)
SEE ALSO MENTAL HEALTH (SERVICES), YOUTH
ROlHL-22021-01 Asthma in families- Behavior analysis of
family interaction pattern
CHILD MORTALITY
SEE CHILDREN, INFANT AND CHILD MORTALITY
CHILD REARING
SEE FAMILY, CHILD REARING
CHILD WELFARE, CHILD CARE PERSONNEL
** P60HL-151 70-05 0008 Support for center for sickle cell
anemia - Pediatric services -Education program
CHILDBIRTH
SEE PREGNANCY, BIRTH
CHILDREN
SEE ALSO FAMILY
ROlHL-01486-23 Quantitative study of T-wave mechanisms
(human, rabbits, dogs, chickens)
POlHL-06285-18 0151 Cardiovascular-respiratory
physiology and biochemistry - Microangiopathy in diabetic
and glucose intolerant children
POlHL-06296-18 0002 Cardiovascular and pulmonary
adaptation to stress - Respiratory muscle blood flow,
mechanics and metabolism (human, dog)
POlHL-06296-18 0003 Cardiovascular and pulmonary
adaptation to stress - Human exercise studies (human,
dogs)
POlHL-06314-17 0060 Immunologic mechanisms in
cardiovascular disease - Strept antigens and infections in
cardiovascular complications (human, animals)
P01HL07293-17 0059 Non-invasive cardiovascular
measurements - Intracardiac blood flow measurement
(human)
ROlHL-07605-16 Congenital heart disease research
program (human, dogs)
POlHL-07895-15 0021 Environmental biomedical research
program - Liquid breathing and lung lavage (human)
POlHL-090 11-15 0018 A research and resource program
in blood - Hepatitis B in normal populations-Epidemiology,
risk factors and transmission
ROlHL-09921-13 Mechanisms related to congestive heart
failure (dogs, human, rat)
M POlHL-10436-13 A multidisciplinary study of congenital
heart disease
** POlHL-10436-13 0001 A multidisciplinary study of
congenital heart disease - Assessment of the outlook for
children with congenital heart disease
** POlHL-10436-13 0005 A multidisciplinary study of
congenital heart disease • Pulmonary physiology in
congenital heart disease (human)
*• POlHL-10436-13 0008 A multidisciplinary study of
congenital heart disease - Physiologic consequences of
chronic hypoxemia (human)
POlHL-10436-13 0009 A multidisciplinary study of
congenital heart disease - Pathophysiology and
morphogenesis of congenital heart disease (human)
ROlHL-10622-12 Volumes and compliance of pulmonary
circulation (human, dogs)
M POlHL-1 1307-12 Biophysical studies in pediatric
cardiology
POlHL-1 1307-12 0002 Biophysical studies in pediatric
cardiology • Cardiac extracellular electrophysiology (human,
dog. chimpanzee)
POlHL-1130712 9001 Biophysical studies in pediatric
cardiology • Core support-computer science
POlHL-1 1307-12 9002 Biophysical studies in pediatric
cardiology - Biomedical engineering
** POlHL-1 13 10-12 0059 Mechanisms of cardiovascular
disease - Contractility-Acute response to diogoxin after
heart surgery (children)
** POlHL-1 13 10-12 0066 Mechanisms of cardiovascular
disease - Measurement of cardiac output by thermodilution
(children)
•* POlHL-1 13 10-12 0076 Mechanisms of cardiovascular
disease - Tratment of depressed cardiac output following
heart surgery (children, puppies)
** POlHL-12373-10 0005 Cardiopulmonary physiology and
pathophysiology - Characterization of fetal and neonatal
myocardium (human, cats)
POlHL-12738-10 0076 Physiologic pharmacology and its
clinical applications - Pediatric cardiac electrophysiology
and pharmacology (human, dogs)
POlHL-12738-10 0127 Physiologic pharmacology and its
clinical applications - Cardiac electrical activity (human,
animals)
ROlHL-13885-08 0005 Cystic fibrosis and pulmonary
disease - Evaluation of lobar pulmonary lavage (human)
CHI
ROlHL-13885-08 0006 Cystic fibrosis and pulmonary
disease - Cell mediated immunity and Pseudomonas
infections in cystic fibrosis (human)
ROlHL-13885-08 9001 Cystic fibrosis and pulmonary
disease - Pulmonary function core facility (infants.
children)
ROlHL-13885-08 9003 Cystic fibrosis and pulmonary
disease - Fiberoptic bronchoscopy core facility (human.
dogs, sheep)
P50HL-14136-07 0003 Pulmonary SCOR-Airways
obstmctive diseases - Acute pediatric respiratory disease
and COLD
> P50HL-14136-07 0017 Pulmonary SCOR-Airways
obstructive diseases - Pediatric airways obstructive disease
(human)
P50HL-14141-05 SCOR for atherosclerosis in childhood
P50HL-14141-05 0001 SCOR for atherosclerosis in
childhood - Clinical implications (infants and children)
* P50HL-14230-07 0088 A/S SCOR-Lipids. atherosclerosis
and thrombosis • Coronary risk factors in school children-
The Muscatine study
P50HL14237-07 0006 Support for arteriosclerosis center
- Drug treatment of familial hyperbetalipoproteinemia
(human)
ROlHL-15047-06 Digital computer analysis of the
electrocardiogram (human)
1 P50HL 15103-07 A/S SCOR-Early natural history of
arteriosclerosis
* P50HL 15103-07 0001 A/S SCOR-Early natural history of
arteriosclerosis - Clinical research-Bogalusa heart study
(children)
ROlHL-15124-05 Genesis of hypertension in renal disease
(human, dogs)
P60HL-1 5 158-07 0025 Comprehensive sickle cell center -
Cardiovascular evaluation of children with sickle cell
disease (human)
P60HL-15160-07 0014 Center for sickle cell disease -
Replacement therapy of opsonin deficiency in sickle cell
anemia (children)
P60HL15169-05 0009 Support for center for sickle cell
disease - Infections in sickle cell anemia (human)
P60HL-15169-05 0014 Support for center for sickle cell
disease - Orthopaedic aspects of sickle cell disease
(human)
P60HL-15169-05 0017 Support for center for sickle cell
disease • Study of the natural histoiy of sickle cell disease
in the home
ROlHL-15308-07 Assays for peptides of lipoproteins
(human)
" ROlHL-15526-05 Respiratory mechanics in children
ROlHL-15614-04 Heredity and oxygen-Effects on health of
heart-lungs (South America)
** P60HL- 15996-06 0004 Cincinnati comprehensive sickle
cell center - School adjustment of sickle cell patients
P60HL-16008-06 0001 Wayne State University
comprehensive sickle cell center - Patient care system
(children, adults)
P60HL-16008-06 0009 Wayne State University
comprehensive sickle cell center - Natural history of sickle
cell anemia (human)
P60HL-16008-06 0011 Wayne State University
comprehensive sickle cell center - Education, screening and
counseling
P60HL-1726904 0042 National heart and blood vessel
research and demonstration center - Social-psychological
smoking deterrents in schools
POlHL-17419-04 0003 Studies on mechanisms of
hemostasis - Characterization of fibrinogen (human)
ROlHL-17487-04 Adrenergic-vasoregulation interactions m
hypertension (human)
ROlHL-17578-04 Exercise performance in children with
heart disease
ROlHL-17705-04 Kallikrein-kinin system in hypertension
(human, rats, dogs)
** ROlHL-17749-03 Adrenocortical factors in human
hypertension (human)
** ROlHL-17776-04 Pulmonary mucus transport in
obstructive lung diseases (human)
ROlHL-17931-04 Normalized body surface potential maps
(children)
ROlHL-18144-03 Preprocessor system for cardiograms
(human)
** P50HL-18323-04 0037 SCOR hypertension center -
Adrenocortical factors in childhood hypertension
** ROlHL-18454-03 Maximal exercise testing in
hyperlipidemic children
M P50HL-19157-02 Studies in cystic fibrosis and
bronchiolitis
P50HL-19171-02 0003 Pulmonary SCOR-Lung injury by
childhood infections - Natural histoiy, host defense defects-
Children with chronic pulmonary disease
P50HL-19171-02 0004 Pulmonary SCOR-Lung injury by
childhood infections - Long-term effects of respiratory
infections in early childhood
ROlHL-19858-03 UMMC-Blood pressure precursors and
consequences (human)
" ROlHL-19870-03 Hypertensive progeny-Physical and
humoral precursor search
R01HL19898-03 Desferrioxamine therapy in thalassemia
(dogs, rats, children)
" ROlHL-19922-03 Childhood determinants of blood pressure
(contdl
•Ejdudes routine methodotojy OR covers only general projects which preclude
"Oiiented siinificantly to above subject.
indexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
CHI
1SS
CHI
Intis aortic balloon pumpini (dogs.
Exetclsa-inducMl bronchospasm In
" ROIHL 19929 03 Hi|h blood pressure In the youn|,
pfevalance and piecuisois (human)
ROIHL 19946 03 Raduction ol Iron overload In
thalassemia (children, rabbits. do|s. monkeys)
ROIHL 19961 03 ManaiemenI ol hemosidetosis In
thalassemia (children, adults)
ROIHL 20000 03 Iron overload in homo/ygous bote
thalassamla (human)
** ROIHL 2000503 Factors In blood pressure levels ol
children
ROIHL 20314 02 Host delense against S pheumoniae in
sickle cell disease (human)
ROIHL 20S33 09 Pathogenesis ol rheumatic lever (human.
rabbits)
•• ROlHl-20803 02
lambs, cats)
ROIHL 21 126 02
children
R23HL'21203'02 EHect ol vasoactive agents on lelt to-
right shunts (lambs)
ROIHL 213S2 02 Community studies ol obstructive lung
disease (human)
ROIHL 2144402 Pulmonary mechanics durrng postnatal
development (human)
** ROlHL-21829 01 Etiology ol obstructive airway disease in
children (also monkeys)
ROIHL'22021 01 Asthma in lamiiies- Behavior analysis ol
lamily interaction pattern
** ROIHL 2273901 Evolution and progression ol pediatric
atherosclerosis •
P60HL'23282'01 0002 Comprehensive hospital/community
sickle cell center Clinical evaluation ol alternate
pathaway ol compliment activation
N01HV1215610 Lipid research clinic
N01HV'121S8-10 Establishment ol a lipid research clinic
NOIHV 22914 08 Establishment ol a lipid research clinic
C^^ILDREN, ADOLESCENCE (12 TO 21 YRS)
SEE ALSO MENTAL HEALTH (SERVICES). YOUTH
P01HL-0880S'15 0044 Regulation ol ventilation and
pulmonary circulation - Neurochemical interactions in
respiratory control (human, dogs, goats)
P50HL 14230-07 0088 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Coronary risk lactors in school children-
The Muscatine study
ROlHL-15528-05 Renin kinetics in hypertensive and
uremic plasma (human, dogs)
ROlHL-17578-04 Exercise pcrtormance in children with
heart disease
R01HL-17818-05 Metabolism ol cholesterol and cholesterol
in man (also rats, monkeys)
** ROIHL- 184 56-03 Cardiovascular lollow-up ol hypertensive
adolescents
POlHL-18574-03 0001 Lipoprotein methodology and
biomedical applications - Ultracentrilugal and
electrophoretic lipoprotein methodology-Applications
** R01HL19859-03 Epidemiological studies, precursors ol
hypertension (human)
** ROlHL-19864-03 0001 Blood pressure ol children and
young adults - Follow up of students from Dormont.
Pennsylvania
Antecedents ol adolescent hypertension
High blood pressure in the young
ROlHL-19869-03
(human)
R01HL-19956-03
(human)
ROlHL-19984-02 Blood pressure and immunogenetic
lactors in the young (human)
ROlHL-20034-03 Hyperlension-Psychophysiologic and
genetic precursors (human)
ROlHL-20159-03 Genetic epidemiology of precursors ol
hypertension (human)
ROlHL-20655-02
children
ROlHL-2115602
lung disease
ROlHL-21352-02
disease (human)
ROlHL-21578-01
adolescent
R23HL-2 1917-01
hypertension
ROlHL-22298-02
ROlHL-22378-01
Autonomic predictors ol hypertension in
Antitrypsin and other causes ol chronic
Community studies ol obstructive lung
Effect of exercise upon the hypertensive
Adrenal steroids in adolescent and adult
Origins of hypertension (human)
Psyco-somatic predictors of CHD in
adolescence (human)
ROlHL-2273901
atherosclerosis
RI8HL-22934-01
hypertension
R23HL-22947-01
Evolution and progression of pediatric
Behavorial approaches to adolescent
Experimental systems to improve youth
behavior (smoking prevention)
NOlHV-12156-10 Lipid research clinic
CHILDREN, INFANT (BIRTH TO 1 YR)
POlHL-07896-15 0036 Environmental biomedical research
program - Respiratory heat loss in deep diving (infants.
dogs)
POlHL-09011-15 0023 A research and resource program
in blood - Evaluation of hepatitis 6 vaccine in endemic
settings (human)
POlHL-10436-13 0005 A mulfidisciplinary study of
congenital heart disease - Pulmonary physiology in
congenital heart disease (human)
POIMI 11307 17 0002 Biophysical studies In pediatric
caidiology Cardiac eilracellular elecliophysiology (human.
dug, chimpan/ee)
POIHL 11310 I? 0056 Mechanisms ol nirdiovascular
disease Cardiac output response to blood pressure
reduction in infants (human)
POIHL 11310 12 0059 Mechanisms ol cardiovascular
dise.ise Contractility Acute response to diogoxin alter
heart surgery (children)
POIHL 11310 12 0061 Mechanisms ol cardiovascular
disease Computer simulation ol transposition ol great
arteries in inlants
POIHL 11310 12 0066 Mechanisms ol cardiovascular
disease Measurement ol cardiac output by thermodilution
(children)
Physiologic pharmacology and its
Cardiac electrical activity (human.
Abnormal hrmnglohin tyndromai
Pulmonary SCUR Airways
Pediatric airways obttructiva dIMau
POIHL 12738 10 0127
clinical applications
animals)
P50HL 1413607 0003
obstructive diseases
and COLD
P50HL 1413607 9006
obstructive diseases
P50HL 1414105 0001
Pulmonary SCOR Airways
Acute pediatric respiratory disease
Pulmonary SCOR Airways
Pediatric lung lunction core
SCOR lor atherosclerosis in
childhood Clinical implications (inlants and children)
P60HL 15169 05 0017 Support lor center for sickle cell
disease Study of the natural history of sickle cell disease
in the home
P60HL 15170 05 0007 Support for center lor sickle cell
anemia Pediatric services- Screening program
** R01HL15526 05 Respiratory mechanics rn children
•* ROIHL 1632904 Cardiac surgical effect on heart function
in infants (human)
ROIHL 17931-04 Normalized body surface potential maps
(children)
R01HL-19203-03 Surgical approach to congenital heart
diseases (dogs, primates)
•* R01HL20803-02 Intra-aortic balloon pumping (dogs,
lambs, cats)
ROlHL-21431-02 Factor II antigen and coagulant activity
(human, animals)
ROlHL-21444-02 Pulmonary mechanics during postnatal
development (human)
CHILDREN, INFANT AND CHILD MORTALITY
ROlHL-15430-05 Cardiopulmonary adaptation of newborns
to altitude (human)
P60HL-16005-05 0021 Comprehensive sickle cell center -
Management of pregnancy in sickle cell anemia (human)
P50HL-191 85-02 0009 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Nasal continuous positive
airway pressure in hyaline membrane disease (human)
CHILDREN, INFANT AND CHILD MORTALITY,
SUDDEN INFANT DEATH SYNDROME
ROlHL-07047-16 Comparative study of cardiac conduction
system (human, birds, mammals)
POlHL-13480-09 0026 Cardiac electrophysiology - Neural
influences on cardiac electrophysiology and contraction
(dog. cat)
POlHL-14985-07 0004 Adaptation to hypoxia - Control of
breathing in respiratory failure (human, dogs)
ROlHL-15430-05 Cardiopulmonary adaptation of newborns
to altitude (human)
ROlHL-16325-03 Breathing patterns in man
** ROlHL-17800-04 Pulmonary reflexes-Central pathways
(cats, dogs, rabbits)
" ROlHL-19225-02 0004 Types and mechanims of
pulmonary hypertension - Structural changes in human
pulmonary circulation (human, animals)
ROlHL-23601-01 Early hypoxia and development of
respiratory control
CHILDREN, INFANT NEWBORN (BIRTH TO 4-6
WKS)
SEE ALSO BLOOD AND RE DISORDERS. ANEMIA APLASTIC
CONGENITAL
SEE ALSO BLOOD AND RE DISORDERS. ANEMIA HEMOLYTIC
CONGENITAL (GENERAL)
SEE ALSO CONGENITAL ABNORMALITIES
SEE ALSO CONGENITAL ABNORMALITIES. RESPIRATORY
DISTRESS SYNDROME
SEE ALSO JAUNDICE NEONATAL aRANSIENT)
SEE ALSO PREGNANCY. PERINATAL
SEE ALSO RESPIRATORY GAS LEVELS. HYPOXIA NEONATORUM
NOlHB-62908-07 Maternal to infant transmission of
hepatitis B (human)
ROlHL-05168-19 Inhomogencity of hemoglobin types
(human)
M POlHL-10436-13 A multidisciplinary study ol congenital
heart disease
** POlHL-10436-13 0001 A multidisciplinary study of
congenital heart disease - Assessment of the outlook for
children with congenital heart disease
** ROlHL-10834-09 Fetal and neonatal pulmonary circulation
(goats)
** R01HL-1190I-12 0009 Effects of metabolic surgery on
the hyperlipidemias - Cholesterol cord blood and family
management program
POlHL-13480-09 0026 Cardiac electrophysiology ■ Neural
influences on cardiac electrophysiology and contraction
(dog. cat)
ROllll I4I3I 18
(human)
P50HI 14136 07 001/
obstructive dis»ai«v
(human)
P50HI 14141 05 0002 SCOR loi allwtostleiosii in
childhood Intrautefine environment ol proband group
(human)
P50HL 14214 0/ Newborn lung center lor hyaline
membrane disi^ase
P50HL 14214 0/ 00?/ Newborn lung center lor hyaline
membrane disease Oral laryngeal chemoreceptors and
resprratory lailure in newborns (human, sheep)
P50HI 14214 0/ 003? Newborn lung center lor hyaline
membrane disease Evoked electroencephalographic
potential rn inlants with HMD (human)
P50HL 14214 07 0034 Newborn lung center lor hyaline
membrane drsease Core Newborn intensive care unit
P50HL 14218 0/ Pulmonary SCOR Newborn lung center
P50HL 14218 07 0004 Pulmonary SCOR Newborn lung
center Metabolism ol inlants with respiratory distress
syndrome (human)
P50HL 14218 07 0005 Pulmonary SCOR Newborn lung
center Prevention of inlection in inlants with respiratory
drstress (human)
P50HL 14218 07 0012 Pulmonary SCOR Newborn lung
center Longitudinal study ol ROS -On-line fetal and
neonatal monitoring (human)
P50HL 15061 07 0013 Response of lung to injury
Exchange transfusion in inlants with respiratory distress
syndrome (human, sheep)
P60HL 1515807 0004 Comprehensive sickle cell center
Expression ol abnormal hemoglobin synthesis in the
neonate and young child
P60HL-15160-07 0013 Center lor sickle cell disease
Immunochemical diagnosis ol hemoglobinopathies (inlants)
P60HL-15162 07 0001 Comprehensive sickle cell center -
Core program -Patient care
P60HL-15168 07 0001 Comprehensive sickle cell disease
center - Screening program (human)
ROIHL 15430-05 Cardiopulmonary adaptation of newborns
to altitude (human)
ROlHL-17629-03 Developmental aspects of cardiovascular
function (human, cats, rabbits)
ROlHL-1775203 Purified human clotting factor IX-
Immunologic studies (human)
P50HL-19185-02 Pulmonary SCOR-Neonatal respiratory
distress syndromes
P50HL-19185-02 0005 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Role and mechanism of
glucocorticoids in fetal lung maturation (human, rabbit)
P50HL-19185-02 0006 Pulmonary SCOR-Neonatal
respiratory distress syndromes Evaluation ol risk lactors
in neonatal respiratory distress (human, sheep)
P50HL-19185-02 0007 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Sodium bicarbonate and
albumin in resuscitation ol preterm inlants (human)
P50HL-19190-02 0001 Pulmonary SCOR -Pathophysiology.
management ol IRDS - Core-Clinical research center
(inlants)
P50HL-19190-02 0002
management of IRDS
dissemination
P50HL-19190-02 0008
management of IRDS
Pulmonary SCOR-Pathophysiology.
Core-Demonstration and
•Excludes routine melhodokigy OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subproiects describing specific research aspects
See Appendix for investigator's name and grant number
Pulmonary SCOR-Pathophysiology.
Hemodynamics and gas exchange-
Determinants of hypotension (human, infant)
** ROlHL-19864-03 0003 Blood pressure of children and
young adults • Heart rate and blood pressure -Consistency
in infancy (human)
** ROlHL-19930-03 A prospective study-Blood pressure in
newborn twins
ROlHL-20337-02 Thromboembolic diseases (human)
ROlHL-20354-02 Direct determination of oxygen tension in
the clinical environment (human, dogs)
ROlHL-20961-02 Hemoglobin Y-chain genes-Evolution and
inducibility (monkeys, human)
** ROlHL-22636-01 Newborn lung function during
mechanical ventilation (human)
ROlHL-22838-01 Post-transfusion hepatitis in newborn
children
CHILDREN, INFANT PREMATURE AND LOW
BIRTH WEIGHT
SEE ALSO CONGENITAL ABNORMALITIES. RESPIRATORY
DISTRESS SYNDROME
SEE ALSO EYE DISORDERS, RETROLENTAL FIBROPLASIA
SEE ALSO PREGNANCY DISORDERS, EMBRYO-FETAL GROWTH-
DEVELOPMENT DISORDERS (SEE ALSO
APPROPRIATE SPECIFICS)
POlHL-07293-17 0059 Non-invasive cardiovascular
measurements - Intracardiac blood flow measurement
(human)
M P50HL-14214-07 Newborn lung center for hyaline
membrane disease
P50HL-14214-07 0013 Newborn lung center for hyaline
membrane disease - Developmental outcome of children
who had HMD as infants
P50HL-14214-07 0020 Newborn lung center for hyaline
membrane disease - Epidermal growth factor effect -Lung
differentiation, maturation (human, rabbit)
P50HL-14214-07 0028 Newborn lung center for hyaline
membrane disease - Relationship of trace metals to
respiratory failure (dog, sheep, human)
(contd)
CHI
** P50HL-14214-07 0030 Newborn lung center for hyaline
membrane disease - Effects of ductal patency-Impedance
cardiography and echocardiography (human)
P50HL-14214-07 0031 Newborn lung center for hyaline
membrane disease ■ Essential fatty acid deficiency and
HMO (human)
P50HL-14214-07 0032 Newborn lung center for hyaline
membrane disease - Evoked electroencephalographic
potential in infants with HMD (human)
** P50HL14214-07 0034 Newborn lung center for hyaline
membrane disease - Core-Newborn intensive care unit
** P50HL 14218-07 0015 Pulmonary SCOR-Newborn lung
center • Long term follow-up of infants surviving RDS-
Neurological outcome (human)
** P50HL15061-07 0013 Response of lung to injury -
Exchange transfusion in infants with respiratory distress
syndrome (human, sheep)
P60HL16005-05 0021 Comprehensive sickle cell center •
Management of pregnancy in sickle cell anemia (human)
P01HL17419-04 0003 Studies on mechanisms of
hemostasis - Characterization of fibrinogen (human)
M P50HL-19185-02 Pulmonary SCOR-Neonatal respiratory
distress syndromes
P50HL-19185-02 0005 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Role and mechanism of
glucocorticoids in fetal lung maturation (human, rabbit)
P50HL-19185-02 0006 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Evaluation of risk factors
in neonatal respiratory distress (human, sheep)
** P50HL-1918502 0007 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Sodium bicarbonate and
albumin in resuscitation of preterm infants (human)
P50HL 19185-02 0009 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Nasal continuous positive
airway pressure in hyaline membrane disease (human)
M P50HL-1918702 Pediatric pulmonary SCOR -Hyaline
membrane disease
** P50HL-19187-02 0007 Pediatric pulmonary SCOR-Hyaline
membrane disease ■ Follow-up study-Infants with hyaline
membrane disease (human)
P50HL1918702 0011 Pediatric pulmonary SCOR-Hyaline
membrane disease ■ Effects of hypoxia and hypercapnia on
developing nervous system (monkey, human)
P50HL19190-02 0008 Pulmonary SCOR-Pathophysiology.
management of IROS ■ Hemodynamics and gas exchange-
Determinants of hypotension (human, infant)
ROlHL-20337-02 Thromboembolic diseases (human)
** R23HL-21405-01 Respiratory muscles in regulation of
infant breathing (human)
ROlHL-21431-02 Factor II antigen and coagulant activity
(human, animals)
ROlHL-22843-01 Pulmonary physiology in liquid ventilation
(lambs)
CHILDREN, MIDCHILDHOOD (6 TO 12 YRS)
P50HL-14230-07 0088 A/S SCOR -Lipids, atherosclerosis
and thrombosis - Coronary risk factors in school children-
The Muscatine study
R01HL19877-02 Prevention of high blood pressure in
children
ROlHL-22528-02 Early risk predictors for chronic
pulmonary disease (human)
CHILDREN, PRESCHOOL (1 TO 6 YRS)
P60HL15162-07 0021 Comprehensive sickle cell center -
Pneumococcal vaccine in sickle cell disease (children)
CHILE
SEE GEOGRAPHICAL SITES, S. AMERICA, CHILE
CHIMERAS
SEE TISSUE MOSAICISM
CHIMPANZEE
SEE MAMMALS, PRIMATES, MONKEYS AND APES
(ANTHROPOIDS, NON-HUMAN), GREAT APES (PONGIDS),
PAN (CHIMPANZEE)*
CHLAMYDIA
** POlHL-0821415 0023 Chemical and biological properties
of lipids ■ Lipids in microorganisms and cell cultures
(hamsters, mosquitoes)
CHLAMYDIA, LYMPHOGRANULOMA VENEREUM
AGENT
POlHL-08214-15 0023 Chemical and biological properties
of lipids ■ Lipids in microorganisms and cell cultures
(hamsters, mosquitoes)
CHLAMYDIA, MENINGOPNEUMONITIS AGENT
POlHL-08214-15 0023 Chemical and biological properties
of lipids - Lipids in microorganisms and cell cultures
(hamsters, mosquitoes)
CHLAMYDIA, PSITTACOSIS AGENT
P01HL0821415 0023 Chemical and biological properties
of lipids - Lipids in microorganisms and cell cultures
(hamsters, mosquitoes)
CHLAMYDIA, TRACHOMA AGENT
POlHL-08214-15 0023 Chemical and biological properties
of lipids ■ Lipids in microorganisms and cell cultures
(hamsters, mosquitoes)
156
CHLAMYDOZOACEAE
SEE CHLAMYDIA
CHLORALOSE
SEE OXOLES. CHLORALOSE
CHLORDIAZEPOXIDE
SEE AZEPINES, DIAZEPINES, CHLORDIAZEPOXIDE
CHLORIDE PUMP
SEE BIOLOGICAL TRANSPORT, ACTIVE TRANSPORT, ION
PUMPS, CHLORIDE PUMP
CHLORIDES
SEE HALOGENS, CHLORINE (COMPOUNDS) SEE ALSO
SPECIFICS
CHLORINE (COMPOUNDS)
SEE HALOGENS, CHLORINE (COMPOUNDS) SEE ALSO
SPECIFICS
P-CHLOROPHENYLALANINE
SEE CYCLIC AMINO ACIDS, PHENYLALANINE, P-
CHLOROPHENYUUNINE
CHLOROQUINE
SEE QUINOLINES, CHLOROQUINE
CHLOROTHIAZIDE
SEE SULFONAMIDES, CHLOROTHIAZIDE
CHLORPROMAZINE
SEE PHENOTHIAZINES, CHLORPROMAZINE
CHLORTHALIDONE
SEE SULFONAMIDES, PHENYLSULFONAMIDES,
CHLORTHALIDONE
CHOLAGOGUES AND CHOLERETICS
SEE BILE. CHOLAGOGUES AND CHOLERETICS
CHOLANATE SERIES
SEE ALSO BILE ACIDS AND SALTS
SEE ALSO CARDIAC GLYCOSIDES AGLYCONES,
BUFADIENOLIDES
ROlHL-23598-01 Dietary fat, cholesterol and bile acid
turnover (rats)
CHOLANATE SERIES, CHENODEOXYCHOLIC
ACID
ROlHL-10894-12 Intestinal bacteria and steroid
metabolism (human, guinea pigs, rabbits, rats)
ROlHL-17818-05 Metabolism of cholesterol and cholesterol
in man (also rats, monkeys)
CHOLANATE SERIES, CHOLATES
SEE ALSO CHOLANATE SERIES, DEOXYCHOLATES
R01HL-02033-23 Regulation of cholesterol esters in blood
and tissues (rat, cattle, human)
ROlHL-17818-05 Metabolism of cholesterol and cholesterol
in man (also rats, monkeys)
ROlHL-21764-01 Ultramicroanalysis of prostaglandins and
related compounds (rats)
CHOLANATE SERIES, DEOXYCHOLATES
RGlHL-06222-18 Clinical and laboratory studies in lipid
metabolism (human, mammals, non-human)
CHOLATES
SEE CHOLANATE SERIES, CHOLATES
CHOLECYSTOKININ
SEE GASTROINTESTINAL HORMONES, PANCREOZYMIN-
CHOLECYSTOKININ
CHOLEIC ACIDS
SEE CHOLANATE SERIES, DEOXYCHOLATES
CHOLELITHS
SEE BILIARY TRACT DISORDERS. CHOLELITHS
CHOLERA TOXIN
SEE IMMUNOLOGY, ANTIGENS BACTERIAL, CHOLERA TOXIN
CHOLERETICS
SEE BILE, CHOUGOGUES AND CHOLERETICS
CHOLESTANE SERIES, CHOLESTANES
R01HL07878-16 Metabolism of neutral sterols (rats,
rabbits)
ROlHL-186 10-03 Early intervention of age related arterial
changes (pigeon)
CHOLESTANE SERIES, CHOLESTANOL
SEE ALSO CHOLESTANE SERIES. CHOLESTEROL
" ROlHL-07878-16 Metabolism of neutral sterols (rats.
rabbits)
** R01HL17818-05 Metabolism of cholesterol and cholesterol
in man (also rats, monkeys)
CHOLESTANE SERIES, CHOLESTEROL
SEE ALSO CHOLESTANE SERIES. HYDROXYCHOLESTEROLS
SEE ALSO CHOLESTANE SERIES. SITOSTEROL
SEE ALSO CHOLESTANE SERIES. BETA-SITOSTEROL
SEE ALSO LIPIDS BLOOD, HYPERCHOLESTEREMIA
SEE ALSO LIPIDS BLOOD, HYPOCHOLESTEREMIA
ROlHL-01803-23 0005 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Immunologic and dietary synergy in the
pathogenesis of atherosclerosis (rabbits)
CHO
ROlHL-01979-22 Arteriosclerosis in zoo animals on
controlled diets (animals)
R01HL02477-23 Biosynthesis and function a< hpids
(microorganisms, rats)
POlHL-03174-23 0010 Mechanisms of acute vascular
reaction to injury - Search for mutagens in the human
blood (bacteria, animals)
** ROlHL-03299-21 Dietary effects on cholesterol metabolism
(rats, rabbits)
R01HL0506218 Lipid metabolism in cultured cells
(human, rats, rabbits)
** ROlHL-05209-18 Lipid metabolism (monkeys)
** ROlHL-05360-19 Cholesterol biosynthesis and its control
in liver (rats)
ROlHL-06221-17 Composition and structure of plasma
lipoproteins (human, turkeys, baboons)
** ROlHL-06222-18 Clinical and laboratory studies in lipid
metabolism (human, mammals, non-human)
P01HL06285-18 0203 Cardiovascular-respiratory
physiology and biochemistry - Pathways of lipid transport
in the blood (animals)
** P01HL0628518 0204 Cardiovascular-respiratory
physiology and biochemistry - Lipoprotein lipase and
triglyceride transport in chylomicrons (guinea pig, rat)
" P01HL06285-18 0205 Cardiovascular-respiratory
physiology and biochemistry ■ Assimilation of cholesterol in
chylomicrons and VLDL (rabbits)
" POlHL-06285-18 0207 Cardiovascular-respiratory
physiology and biochemistry ■ Feedback control of
cholesterol synthesis in non-hepatic tissues (animals)
ROlHL-06481-15 Lipid metabolism (human, rats)
** P01HL06835-17 0015 Cardiovascular disease - Plasma
cholesterol esterification in canine atherosclerosis
P01HL06835-17 0020 Cardiovascular disease - Lipid
metabolism (rats)
P01HL-0S835-17 0021 Cardiovascular disease - Animal
study in atherosclerosis (dog. guinea pig)
POlHL-06835-17 0063 Cardiovascular disease • Studies
on prostaglandins (human, rabbits)
POlHL-0683517 0064 Cardiovascular disease - Studies
in atherosclerosis (human, animals)
** ROlHL-0863415 Enzymic cholesterol synthesis (human,
rats, protozoa, yeast)
M P01HL0897414 Natural and experimental atherosclerosis
POlHL-08974-14 0005 Natural and experimental
atherosclerosis - Atherosclerosis, coronary heart disease
arid sudden death (human)
POlHL-0897414 0024 Natural and experimental
atherosclerosis - Atherosclerosis, sterol and lipoprotein
metabolism in nonhuman primates
" ROlHL-09610-14 Control of cholesterol metabolism-Bile
acid transport
ROlHL-09744-14 Experimental vascular sclerosis
(monkeys, rabbits)
** ROlHL-10642-18 Plasma cholesterol metabolism (human,
macaca)
** ROlHL-10894-12 Intestinal bacteria and steroid
metabolism (human, guinea pigs, rabbits, rats)
** ROlHL-1094013 Lipid transport (rabbits. caMfe. chickens)
** POlHL-11310-12 0101 Mechanisms of cardiovascular
disease - Molecular pathogenesis of vascular disease
ROlHL-1189711 Pathogenesis of experimental
atherosclerosis (rabbits, guinea pigs)
ROlHL-11901-12 0001 Effects of metabolic surgery on
the hyperlipidemias ■ Partial ileal bypass (human)
** ROlHL-11901-12 0004 Effects of metabolic surgery on
the hyperlipidemias - Ileal bypass-Cholesterol dynamics
studies (rats, rabbits, dogs)
ROlHL-1190112 0012 Effects of metabolic surgery on
the hyperlipidemias - Ileal bypass-Animal atherosclerosis
implications (pigeons, dogs, rabbits)
ROlHL-11901-12 0013 Effects of metabolic surgery on
the hyperlipidemias ■ Human cholesterol and bile acids
dynamics-lleal bypass
** ROlHL-11901 12 0015 Effects of metabolic surgery on
the hyperlipidemias - Portacaval shunt for cholesterol
reduction (dogs, rabbits)
ROlHL-11901-12 0018 Effects of metabolic surgery on
the hyperlipidemias - Jejunoileal bypass -Postoperative
complications (human)
** ROlHL-11901-12 0019 Effects of metabolic .surgery on
the hyperlipidemias - Cholesterol, bileacids. lipoproteins in
obese humans
ROlHL-11901-12 0020 Effects of metabolic surgery on
the hyperlipidemias ■ Jejuno-ileal bypass-Endogenous
animal model of obesity (rats)
ROlHL-12399-13 Specific fatty acids and cholesterol
metabolism (gerbils. rats)
ROlHL-12528-10 NMR relaxation of liquid crystal systems
ROlHL-12740-10 Hypocholesterolemic agents-
Stereochemistry (rats)
** ROlHL-12745-10 Enzymes and inhibitors of cholesterol
biosynthesis (rats, human, swine)
ROlHL-12760-09 Surface studies of membrane lipids and
proteins
ROlHL-12869-09 Arterial metabolism, diabetes and
atherogenesis (rats, rabbits)
POlHL-13262-07 0016 Arterial wall in atherosclerosis -
Lipids in elastin preparations from atherosclerotic plaques
(human, animals)
R01HL13405-09 Regulation of lipid metabolism in the
lung (rats)
(contd)
•Excludes routine methodology OR covers only general projects which preclude i
"Onented significantly to above subject.
ndexing at the specific level.
M Grant has subprojects describing specific researcli aspects.
See Appendix for investigator's name and grant number.
CNI
1S7
CHO
ROIHL 13974 0/ Ventnculnf prtmitui* tolls ind sudden
corontry death (humen)
ROIHL 141 1 1 0/ Cholesterol esters in mtnibranes and
atherosclerosis (human, swine)
ROIHL 14126 17 EMect ot lunction on iiatts and impUnls
of collaien (dogs, monkeys)
PSOHL 14141 OS 0003 SCOR loi atherosclerosis in
childhood Detection of abnormalities in lipid metabolism
(human, rabbits, rats)
PSOHL 14141 Oi 0008 SCOR loi atherosclerosis in
childhood Core laboratory
PSOHL 14164 07 A/S SCOR Comparative and enpenmenlal
atherosclerosis
PSOHL 14164 07 0027 A/S SCOR Comparative and
experimental atherosclerosis Hyper and
hyporesponsiveness to dietary cholesterol (squirrel monkey)
PSOHL 14164 07 0028 A/S SCOR Comparative and
experimental atherosclerosis Hyper and
hyporesponsiveness to dietary cholesterol (African green
monkey)
PSOHL 14164 07 0029 A/S SCOR Comparative and
experimental atherosclerosis Development ol pigeon
substrains
PSOHL 14164 07 0030 A/S SCOR Comparative and
experimental atherosclerosis Morphology, angiochemistry
Diet induced lesions in African green monkey
PSOHL 1416407 0031 A/S SCOR Comparative and
experimental atherosclerosis Changes in endothelial
permeability associated with atherosclerosis (pigeon)
PSOHL 14164 07 0032 A/S SCOR-Comparative and
experimental atherosclerosis Plasma cholesterol, lesion
regression and vascular function (Rhesus monkey)
PSOHL 14164-07 0033 A/S SCOR-Comparative and
experimental atherosclerosis - Comparative studies of
lipoprotein distribution and metabolism (monkeys)
PSOHL-14164-07 0034 A/S SCOR-Comparative and
experimental atherosclerosis Core lipid analytic laboratory
P50HL-14164-07 0035 A/S SCOR-Comparative and
experimental atherosclerosis Lipid metabolism -Interaction
with arterial metabolism (monkey, pigeon)
P50HL-14164-07 0036 A/S SCOR-Comparative and
experimental atherosclerosis - Connective tissue
metabolism "Interaction with arterial metabolism (monkeys)
PSOHL14164-07 0037 A/S SCOR-Comparative and
experimental atherosclerosis - Genetic control of plasma
cholesterol -Interaction of dietary fatty acid (monkey)
PS0HL14164-07 0038 A/S SCOR-Comparative and
experimental atherosclerosis - Peripheral vascular studies-
Cholesterol, lesion regression, vascular function
PS0HL14164-07 0041 A/S SCOR-Comparative and
experimental atherosclerosis - Nonhuman primate pediatric
atherosclerosis risk factor
PSOHL-14164-07 0042 A/S SCOR-Comparative and
experimental atherosclerosis - Comparative cardiology
laboratory (monkeys)
P50HL-1419707 0005 Support for center of research on
arteriosclerosis - Lipoprotein biosynthesis and degradation
in VIVO and in vitro (human, animal)
P50HLI4197-07 0006 Support for center of research on
arteriosclerosis - Diets and drugs affecting lipid
metabolism (human)
P50HL-1419707 0007 Support for center of research on
arteriosclerosis - Metabolic defects in familial
hyperlipoproteinemias (human)
P50HL1423007 0088 A/S SCOR-Lipids. atherosclerosis
and thrombosis - Coronary risk factors in school children-
The Muscatine study
P50HL-14230-07 0092 A/S SCOR-Lipids. atherosclerosis
and thrombosis ■ Tissue lipids-Cell culture studies
(human)
P50HL1423007 0093 A/S SCOR-Lipids. atherosclerosis
and thrombosis - Clinical studies involving cellular lipid
content (human)
P50HL-14230-07 0094 A/S SCOR-Lipids. atherosclerosis
and thrombosis - Studies of atherosclerosis and regression
(monkeys)
P50HL-14230-07 9001 A/S SCOR-Lipids. atherosclerosis
and thrombosis - Core lipid laboratory
P50HL-14236-05 0001 Prevention of premature
arteriosclerosis • Metabolism and transport of cholesterol
and vitamin A (human, rats)
P50HL14236-05 0008 Prevention of premature
arteriosclerosis - Lipoproteins of cell membranes (human)
P50HL-14236-05 0009 Prevention of premature
arteriosclerosis - Clinical studies on cholesterol metabolism
(human)
P50HL-14237-07 0005 Support for arteriosclerosis center
■ Genetic determinants of apolipoprotein variability in
lipoproteins (human)
P50HL-14237-07 0007 Support for arteriosclerosis center
- Core laboratories
R01HL14313-07 Apoproteins of triglyceride rich
lipoproteins (human, squirrel monkeys, rats)
ROlHL-14378-07 Lipemias and reconstructive cardiac
surgery (human)
ROlHL'14781-08 Lipid deposition in mammalian cells
(mice)
ROlHL-14820-07 Factors affecting physiology of biological
membranes (human)
P50HL-15062-07 0007 Study of lipoproteins, artery wall,
and atherosclerosis - Physical chemistry of lipid-protein
interaction (human)
PSOHL 1S062 07 0018
and atherosclerosis
monkeys
PSOHL 15062 0/ 0019
and atherosclerosis
Study ol lipoproleins. artery wall.
Reversal ol atherosclerosis in
Study ol lipoproteins, artery wall.
laclois leguliiting lipoprotein smooth
muscle cell interaction (monkey)
PSOHL 15103 07 0013 A/S SCOR larly natural history ol
arteriosclerosis Liperimcnial models ol atherosclerosis
(monkeys)
ROIHL 151 74 06 CV disease epidemiology- Second
generation studies (human)
ROIHL 15263 06 Lecithin Cholesterol acetyltranilerase
(human, rabbits)
POIHL 1526505 0003 Program on surgical control ol the
hyperlipidemias Central lipid laboratory
ROIHL 153 76 06 Intermediary metabolism ol sterols (mice)
ROIHL 154 78 05 Lipid llux and collagen synthesis in
atherosclerosis (rabbits)
ROIHL 15504 05 Animal model lor studies on averting
atherosclerosis (swine)
POIHL 1559605 0018 Coagulation. Iibrinolysis.
hemostasis and hepatitis Increased plasma lipids on
blood coagulation and thrombosis (human, animals)
ROIHL 15797 05 Lipid metabolism and atherosclerosis in
primates (monkeys, human, squirrels)
ROIHL 15895 05 In vitro study ol lipoproteins in vascular
disease (human, animals)
ROIHL 1593006 Hormonal control ol lipid and lipoprotein
synthesis (rats)
ROIHL 15949-05 Lipoprotein metabolism in relation to
atherosclerosis (human, baboons)
ROIHL 15965-06 Experimental atherosclerosis and elastin
metabolism (chicks)
ROIHL 16059-06 Structure and lunction of serum
lipoproteins (cattle, human)
ROIHL- 162 94 04 Effectors of cholesterol synthesis (rats)
ROlHL'16364-04 Regulation of lipid biosynthesis and
transport (rats, swine, Xenopus)
R01HL-16S88-05 Collagen synthesis in atherosclerosis
(dogs, rats, rabbits, human)
ROlHL-16660-06 Phospholipid-cholesterol and
phospholipid'protein interactions
ROlHL-16796-05 Cholesterol regulation by HMG-CoA
reductase (rats, human)
P01HL-16851-04 0001 Human red cell membrane in
health and disease - Rheology of erythrocyte membrane
(human, amphiuma)
P60HL-17269-04 0013 National heart and blood vessel
research and demonstration center - Peptide synthesis
laboratory (human)
P50HL- 172 69-04 0017 National heart and blood vessel
research and demonstration center - Cell membrane (dogs,
rabbits)
ROlHL-17332-04 Use of the gut for therapy of coronary
artery disease (mammals)
R01HL17564-03 Unsaturated fats-Mode of
hypocholesterolemic action (minipig)
ROlHL-17576-04 Role of sphingomyelin in biomembranes
and bilayers (rats, other mammals)
ROlHL-17580-04 The impact of stress on coronary heart
disease (men)
ROlHL-17721-04 Effect of sex hormones on vascular
connective tissue (rats)
ROlHL-178 18-05 Metabolism of cholesterol and cholesterol
in man (also rats, monkeys)
R01HL1788204 Regulation of HMG-COA reductase and
sterol synthesis (human, mammals)
ROlHL-18048-04 Dynamics of artificial and biological
membranes (human)
ROlHL-18094-04 Regulation of cholesterol biosynthesis
(rats)
ROlHL-181 57-04 Subcellular events in atherosclerosis
(human, rabbits, calves)
ROlHL-182 19-04
(rats)
ROlHL-18235-03
factors (human)
R01HLI8255-04
transport (models)
P50HL183 18-03 0015 Pathogenesis and complications of
hypertension - Cultured smooth muscle cells and
microvessel metabolism (mammals)
ROlHL-18553-03 Membrane defects in familial
hypercholesteremia (human)
POlHL-18574-03 Lipoprotein methodology and biomedical
applications
POlHL-18574-03 0004 Lipoprotein methodology and
biomedical applications - fine structure and metabolism of
lipoproteins-EM studies (guinea pigs)
ROlHL-186 10-03 Early intervention of age related arterial
changes (pigeon)
ROlHL-18623-12 Physical chemistry of biologically active
lipids (bacteria, plant, cattle, human)
ROlHL-1863602 Fatty acids and cholesterol transport
(rats)
POlHL-18645-03 0001 Biology of the artery wall and
atherosclerosis - Primate arterial smooth muscle and
atherosclerosis
ROlHL-18682-03 Protein kinase and cholesterol
metabolism in aorta (rabbits)
ROlHL-18687-03 Pathophysiology of genetic
hypertriglycerinemias (human)
Regulation of cholesterol metabolism
Cardiovascular fitness and other risk
Lipid-protein interactions and calcium
ROIHI 18773 03 Centtir helaioienaity ol and lipa-.n
Athfrro^f-lero-.i^ (human)
pniMI IHH2/02 0005 Platelet ve«ul wall inlaiatlions in
Ihrumboieneiis Platelal vtiial wall inlaiaclHini in
Ihromboganiili (human)
ROim 18878 03 Familial hypercholestaramia Studies ol
libiohlast% (human)
ROIHI 18923 U2 Steroid induced hyperlipidemia and
hypertension (human, rats)
ROIHI 19063 03
(rat hepatocytes)
ROIHL 19083 02
Cholesterol and lipoprotein melaboli'.m
Rapid sperilic micro measurement ol
Regression of chronic atherosclerosis
'Excludes routine methodology OR covers only general projects which preclude indexing
•^Oriented significantly to above subject.
at the specific level.
blood cholesterol
ROIHI 19109 03
(rabbits)
ROIHL 19175 03 Pituitary modulation ol micro and macro
vascular disease (human, rats)
ROIHL 19223 03 Control ol cholesterogenesis in leukocytes
and liver (rats, human)
POIHL 19242 02 0002 Study ol vascular smooth muscle
Vascular smooth muscle response to serum lipoproteins
(rats)
P50HL 1936202 A/S SCOR Atherosclerosis in nonhuman
primates
P50HL 19362 02 0001 A/S SCOR Atherosclerosis in
nonhuman primates Effects of infant nutrition on
atherosclerosis (baboons)
P50HL 19362 02 0002 A/S SCOR-Atherosclerosis in
nonhuman primates Infant caloric intake, adipose tissue
development and atherosclerosis (baboon)
PSOHL 19362 02 0003 A/S SCOR Atherosclerosis in
nonhuman primates Heritability of characters related to
atherosclerosis (baboons)
PSOHL 1936202 0004 A/S SCOR Atherosclerosis in
nonhuman primates Selective breeding for characters
related to atherosclerosis (baboons)
P50HL-19362-02 0005 A/S SCOR-Atherosclerosis in
nonhuman primates Hybridization to produce primate
model of atherosclerosis (baboon. Rhesus)
P50HL19362-02 0006 A/S SCOR-Atherosclerosis in
nonhuman primates Effects of cigarette smoking on
atherosclerosis (baboon)
P50HL-19362-02 0009 A/S SCOR-Atherosclerosis in
nonhuman primates - Cholesterol metabolism and
intestinal microflora (baboon)
P50HL-19362-02 0013 A/S SCOR-Atherosclerosis in
nonhuman primates - Core laboratory-Lipid biochemistry
(baboons)
R01HL19381-03 Pathogenesis of viral induced
atherosclerosis (human, chicken)
ROlHL-19936-02 Unsaturated fatty acid biosynthesis in
the aorta (rats)
ROlHL-19984-02 Blood pressure and immunogenetic
factors in the young (human)
R01HL-200ei-02 Serum lipoproteins and cell cholesterol
metabolism (rats, human)
ROlHL-20183-02 Portacaval shunt as treatment for
hyperlipemia (pigs)
ROlHL-2030303 Cholesterol distribution in erythrocyte
membrane (human, animals)
ROlHL-20350-02 Crystal structure of lipids -Cholesterol
ROlHL-20391-03 Polydisperse LDL-Structure, metabolism
and function (human)
ROlHL-2041803 Serum cholesterol binding reserve in
diabetes (human)
ROlHL-2048303 Sterol balance and cholesterol absorption
in diabetics (human)
ROlHL-20488-03 Cholesterol metabolism in diabetic man
ROlHL-20662-02 Physical activity, fitness and
epidemiology of CHD
ROlHL-20725-02 Mechanisms and cellular functions of ion
transport
ROlHL-20910-02 The alternative diet for coronary disease
prevention (human)
POlHL-20948-02 Molecular basis of cholesterol
metabolism
POlHL-20948-02 0001 Molecular basis of cholesterol
metabolism - Biochemical and ultrastructural
characterization of LOL in human fibroblasts
POlHL-2094802 0002 Molecular basis of cholesterol
metabolism - LDL pathway in cell lines with informative
properties other than fibroblasts
POlHL-20948-02 0003 Molecular basis of cholesterol
metabolism - LDL pathway in vivo (human, rats, guinea
pigs)
POlHL-20948-02 0004 Molecular basis of cholesterol
metabolism - Genetic analysis of the LDL pathway (human)
POIHL 20948-02 9001 Molecular basis of cholesterol
metabolism - Tissue culture core laboratory
POlHL-20948-02 9002 Molecular basis of cholesterol
metabolism • Microscopy core laboratory
POlHL-20993-02 Population dynamics of arterial cells in
atherogenesis
POlHL-20993-02 0008 Population dynamics of arterial
cells in atherogenesis ■ Angiotoxicity of cholesterol
oxidation in atherogenesis (rabbits)
P50HL-2100602 Specialized center of research in
arteriosclerosis
P50HL-2100602 0002 Specialized center of research in
arteriosclerosis - Turnover and metabolism of cholesterol in
man
(contd)
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
CHO
ROlHL-2124602 Roles of cholesterol and its metabolic
regulation (CHO cell mutants)
R23HL-21251-01 Metabolism of neutral lipids in the
pulmonary alveolus (rabbits)
R23HL-21279-02 Angiographic estimation of
atherosclerotic wall thickness
ROlHL-21592-01 Lipoproteins and coagulation factors in
atherosclerosis (pigeons)
ROlHL-21764-01 Ultramicroanalysis of prostaglandins and
related compounds (rats)
ROlHL-21912-01 Biosynthesis of lipoic acid and
atherosclerosis (birds, chick embryos)
ROlHL-2205201 Organization of free cholesterol in serum
lipoproteins (human, dogs)
ROlHL-22053-02 The disordered lipid metabolism of
diabetes mellitus (chickens, mammals, human)
ROlHL-22121-02 Dyslipoproteinemia in diabetes and
vascular disease (human)
ROlHL-22378-01 Psycosomatic predictors of CHD in
adolescence (human)
' ROlHL-22474-01 Cholesterol metabolism and
atherosclerosis (rats, human, rabbits)
■ ROlHL-2256701 Validation of a cholesterol absorption
method in man
• ROlHL-22570-01 Interactions of sterols in biological
systems (human)
ROlHL-22607-01 Role of apolipoprotein E in lipoprotein
metabolism (human)
Cellular and molecular biology of
• Sterol metabolism in tissue
POlHL-22633-01 0002
lipoprotein metabolism
culture cells
POlHL-22633-01 0003
lipoprotein metabolism
Cellular and molecular biology of
^_^ Sterol metabolism in platelets and
megakaryocytes (human, rabbits, guinea pigs)
POlHL-22633-01 0004 Cellular and molecular biology of
lipoprotein metabolism - Lipid-lipid and lipid-protein
interactions in serum lipoproteins (human, rats)
ROlHL-22682-01 Structure and function of high density
lipoprotein (human, rat)
R01HL-22739-01
atherosclerosis
ROlHL-22771-01
(cattle)
ROlHL-22983-01 Studies on the catabolism of plasma
lipoproteins (rats)
ROlHL-23003-01 Bulk-surface distribution of cholesteryl
Evolution and progression of pediatric
Thrombogenic phospholipid surfaces
Membrane biochemistry of RH antigens
Voltage dependent conductance in
Dietary fat, cholesterol and bile acid
esters
ROlHL-23 108-01
(human)
ROlHL-23183-01
membranes
ROlHL-23598-01
turnover (rats)
ROlHL-23945-06 Pathologic effects on cells of modified
lipoproteins (rats, human)
N01HV12157-14 Lipid research clinic (human)
NOlHV-22971-07 Prevention of coronary heart disease
(human)
NOlHV-22976-07 Multiple risk factor intervention trial,
prevention of coronary heart disease
NOlHV-22977-08 Intervention trial for the prevention of
coronary heart disease (human)
N01HV-22979-07 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22980-06 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22981-10 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22982-07 Intervention trial for prevention of
coronary heart disease (human)
NOlHV-22983-07 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-33101-06 Development and conduct of a multiple
risk factor intervention trial (human)
NOlHV-33105-09 Intervention trial for prevention of
coronary heart disease (human)
NOlHV-33106-06 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-33 108-04 Prevention of coronary heart disease
(human)
NOlHV-33109-04 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-331 10-04 Prevention of coronary heart disease
(human)
N01HV-42930-09 Risk factor intervention trial for the
prevention of CHD (human)
NOlHV-42932-05 Risk factor intervention trial for the
prevention of CHD (human)
NOlHV-42933-09 Multiple risk factors in coronary heart
disease (human)
CHOLESTANE SERIES, CHOIESTEROI ANALOGS
ROlHL-21246-02 Roles of cholesterol and its metabolic
regulation (CHO cell mutants)
CHOLESTANE SERIES, CHOLESTEROL ESTERS
** ROlHL-02033-23 Regulation of cholesterol esters in blood
and tissues (rat, cattle, human)
ROlHL-03299-21 Dietary effects on cholesterol metabolism
(rats, rabbits)
** ROlHL-03734-18 Metabolism of arterial tissue in
atherosclerosis (rabbits)
158
ROlHL-05360-19 Cholesterol biosynthesis and its control
in liver (rats)
POlHL-0628518 0203 Cardiovascular-respiratory
physiology and biochemistry - Pathways of lipid transport
in the blood (animals)
POlHL-06285-18 0205 Cardiovascular-respiratory
physiology and biochemistry ■ Assimilation of cholesterol in
chylomicrons and VLDL (rabbits)
POlHL-06285-18 0207 Cardiovascular-respiratory
physiology and biochemistry - Feedback control of
cholesterol synthesis in non-hepatic tissues (animals)
POlHL-06835-17 0015 Cardiovascular disease - Plasma
cholesterol esterification in canine atherosclerosis
P01HL06835-17 0020 Cardiovascular disease - Lipid
metabolism (rats)
ROlHL-1016013 Origins of atherosclerosis (human)
ROlHL-10642-18 Plasma cholesterol metabolism (human,
macaca)
' ROlHL-10933-13 Fat metabolism and atherosclerosis
(rabbits, cattle, human, rats)
' POlHL-1326207 0025 Arterial wall in atherosclerosis ■
Phospholipid and cholesterol esters
ROlHL-13722-08 Acid and alkaline lipases in aortas (rats,
rabbits, human)
' RC1HL14111-07 Cholesteryl esters in membranes and
atherosclerosis (human, swine)
P50HL14164-07 0031 A/S SCOR -Comparative and
experimental atherosclerosis - Changes in endothelial
permeability associated with atherosclerosis (pigeon)
P50HL-14164-07 0033 A/S SCOR-Comparative and
experimental atherosclerosis - Comparative studies of
lipoprotein distribution and metabolism (monkeys)
P50HL 14164-07 0035 A/S SCOR-Comparative and
experimental atherosclerosis - Lipid metabolism-Interaction
with arterial metabolism (monkey, pigeon)
P50HL-14164-07 0036 A/S SCOR-Comparative and
experimental atherosclerosis ■ Connective tissue
metabolism-Interaction with arterial metabolism (monkeys)
P50HL-14164-07 0037 A/S SCOR-Comparative and
experimental atherosclerosis - Genetic control of plasma
cholesterol-Interaction of dietary fatty acid (monkey)
P50HL-14230-07 0092 A/S SCOR -Lipids, atherosclerosis
and thrombosis - Tissue lipids-Cell culture studies
(human)
P50HL-14237-07 0002 Support for arteriosclerosis center
- Interactions of lipoprotein particles with vascular surface
(human, rat)
P50HL-1423707 0003 Support for arteriosclerosis center
- Structure of lipoproteins and apolipoproteins (human,
rabbits)
R01HL14313-07 Apoproteins of triglyceride rich
lipoproteins (human, squirrel monkeys, rats)
R01HL14781-08 Lipid deposition in mammalian cells
(mice)
Study of lipoproteins, artery wall,
Reversal of atherosclerosis in
CHO
P50HL-15062-07 0018
and atherosclerosis
monkeys
P50HL-15062-07 0019
and atherosclerosis
Study of lipoproteins, artery wall.
Factors regulating lipoprotein-smooth
muscle cell interaction (monkey)
R01HL15448-06 Surgical and metabolic aspects of
venous grafts, (dogs, monkeys, rabbits)
ROlHL-15478-05 Lipid flux and collagen synthesis in
atherosclerosis (rabbits)
ROlHL-15895-05 In vitro study of lipoproteins in vascular
disease (human, animals)
ROlHL-16807-02 Lipid structure of normal and
hyperlipoproteins (human)
P60HL-1 726904 0009 National heart and blood vessel
research and demonstration center ■ Physical methods
laboratory (high density lipoproteins)
ROlHL-17371-05 Regualtion of cholesteryl ester levels in
the aorta (swine)
P50HL- 183 18-03 0014 Pathogenesis and complications of
hypertension - Arterial metabolism and atherogenesis (rat.
rabbit)
ROlHL-18682-03 Protein kinase and cholesterol
metabolism in aorta (rabbits)
R01HL-19083-02 Rapid specific micro measurement of
blood cholesterol
POlHL-19242-02 0002 Study of vascular smooth muscle -
Vascular smooth muscle response to serum lipoproteins
(rats)
R01HL19250-03 Mechanism of plasma cholesterol
esterification (human)
ROlHL-19936-02 Unsaturated fatty acid biosynthesis in
the aorta (rats)
ROlHL-20350-02 Crystal structure of lipids-Cholesterol
POlHL-20948-02 0002 Molecular basis of cholesterol
metabolism ■ LDL pathway in cell lines with informative
properties other than fibroblasts
POlHL-20993-02 0006 Population dynamics of arterial
cells in atherogenesis ■ Mechanism of regression of
atherosclerosis by diet and injury (swine)
P50HL-2100602 0004 Specialized center of research in
arteriosclerosis ■ Regulation of growth of human arterial
smooth muscle cells by platelets
R23HL-21251-01 Metabolism of neutral lipids in the
pulmonary alveolus (rabbits)
ROlHL-22121-02 Dyslipoproteinemia in diabetes and
vascular disease (human)
ROlHL-22570-01 Interactions of sterols in biological
systems (human)
ROlHL-22618-01 Role of apolipoproteins in
hypertriglyceridemia (human)
ROlHL-22739-01
atherosclerosis
ROlHL-22847-01
linoleic acid
ROlHL-23003-01
esters
Evolution and progression of pediatric
Test for adherence to diets rich in
Bulk-surface distribution of cholesteryl
'Excludes routine methodology OR covers only general projects which preclude
"Oriented significantly to above subject
ROlHL-21513-02
rats, swine)
indexing at the specific level.
Metabolism of trans fatty acids (human.
CHOLESTANE SERIES, CHOLESTEROL INHIBITORS
SEE ALSO PYRIDINE CARBOXYLIC ACIDS, NICOTINIC ACID
ROlHL-02033-23 Regulation of cholesterol esters in blood
and tissues (rat, cattle, human)
POlHL-06285-18 0207 Cardiovascular-respiratory
physiology and biochemistry - Feedback control of
cholesterol synthesis in non-hepatic tissues (animals)
P01HL0683517 0026 Cardiovascular disease ■
Lipoproteins (human, guinea pig)
POlHL-08214-15 0027 Chemical and biological properties
of lipids Biological functions dial lipids (swine, rats,
plants)
ROlHL-08888-12 Cooperative study of drugs and coronary
heart disease (men)
** ROlHL-0889210 Cooperative study of drugs and coronary
heart disease
R01HL10445-09 Cooperative study of drugs and coronary
heart disease (men)
R01HL10705-09 Cooperative study of drugs and coronary
heart disease (men)
R01HL11372-08 Cooperative study of drugs and coronary
heart disease (men)
ROlHL-1190112 0004 Effects of metabolic surgery on
the hyperiipidemias ■ Ileal bypass -Cholesterol dynamics
studies (rats, rabbits, dogs)
" ROIHLI 1901-12 0006 Effects of metabolic surgery on
the hyperiipidemias ■ Drug therapy with ileal bypass
(rabbits)
** ROlHL-1274010 Hypocholesterolemic agents-
Stereochemistry (rats)
** ROlHL-12745-10 Enzymes and inhibitors of cholesterol
biosynthesis (rats, human, swine)
" ROlHL-13654-08 Antilipemic regimes in peripheral
arteriosclerosis (human)
ROlHL-1372208 Acid and alkaline lipases in aortas (rats,
rabbits, human)
P50HL-14197-07 0006 Support for center of research on
arteriosclerosis - Diets and drugs affecting lipid
metabolism (human)
P50HL-14230-07 0093 A/S SCOR-Lipids, atherosclerosis
and thrombosis ■ Clinical studies involving cellular lipid
content (human)
** P50HL-14236-05 0009 Prevention of premature
arteriosclerosis - Clinical studies on cholesterol metabolism
(human)
** P50HL14237-07 0006 Support for arteriosclerosis center
- Drug treatment of familial hyperbetalipoproteinemia
(human)
P50HL-1 5062-07 0018 Study of lipoproteins, artery wall,
and atherosclerosis - Reversal of atherosclerosis in
monkeys
ROlHL-15374-03 Cooperative study of drugs and coronary
heart disease (human)
ROlHL-15376-06 Intermediary metabolism of sterols (mice)
** ROlHL-15476-05 Mechanism and control of sterol
biosynthesis (rats)
R01HL-15512-06 Drug treatment of stenosing primate
atherosclerosis (rabbits, monkeys)
** ROlHL-16294-04 Effectors of cholesterol synthesis (rats)
** R01HL1658704 Cholesterol binding saponins and
atherosclerosis (monkeys)
ROlHL-16796-05 Cholesterol regulation by HMG-CoA
reductase (rats, human)
** ROlHL-17332-04 Use of the gut for therapy of coronary
artery disease (mammals)
** R01HL17564-03 Unsaturated fats-Mode of
hypocholesterolemic action (minipig)
POlHL-18574-03 0006 Lipoprotein methodology and
biomedical applications - Lipoprotein transformation,
lipolytic enzymes, diet and lipid lowering agents
POIHL 18827-02 0005 Platelet vessel wall interactions in
thrombogenesis - Platelet vessel wall interactions in
thrombogenesis (human)
ROlHL-19010-03 Metabolism and cell biology of lung
surfactant system (rabbits, sheep)
ROIHL 19223-03 Control of cholesterogenesis in leukocytes
and liver (rats, human)
ROlHL-19936-02 Unsaturated fatty acid biosynthesis in
the aorta (rats)
** ROlHL-20183-02 Portacaval shunt as treatment for
hypertipemia (pigs)
** POlHL-20993-02 0004 Population dynamics of arterial
cells in atherogenesis - Modifications of cholesterol balance
related to arterial cell divisions (swine)
** POlHL-20993-02 0005 Population dynamics of arterial
cells in atherogenesis Drugs other than hypolipidemic
drugs affecting atherosclerosis (swine, rabbits)
R23HL-21251-01 Metabolism of neutral lipids in the
pulmonary alveolus (rabbits)
(oontd)
M Grant has subpiojeds describing specific research aspects.
See Appendix for investigator's name and grant number.
CHO
** ROIHL 22S32 01 Inhibltois ol cholesttrol bioiynthesli
(iits. mic*. y«>sl)
** ROIHL 22682 01 Sliuctuie tnd luncliun ot hi|h density
lipoprotein (human, latl
NOIHV 121S6 10 Lipid leseaich clinic
NOIHV 121S8 10 Establishment at a lipid rasiireli clinic
NOIHV 12I&909 Lipid reseaich clinic
NOIHV 12160 IS Establishment ol a lipid research clinic
NOIHV 22913 09 Lipid leseairh clinic
NOIHV 22914 08 tslablishmeni ot a lipid leseerch clinic
NOIHV 2291b 11 Establishment ol lipid lesearch clinic
NOIHV 32931 09 Establishment ot a lipid research clinic
centei
CHOLESTANE SERIES, CHOLESTEROL
INHIBITORS, COLESTIPOL
P50HL 1419; 0/ 0006 Support tnr center ot research on
arteriosclerosis Diets and drugs altecting lipid
metabolism (human)
P50HL 1423707 0006 Support lor arteriosclerosis center
Drug treatment of familial hyperbetalipoproteinemia
(human)
ROIHL 1530807 Assays tor peptides of lipoproteins
(human)
PSOHL'2100602 0001 Specialized center ot research in
arterwsclerosis Clinic and core prografh
ROIHL 22748 01 Effect of bile sequestration on VLDL
metabolism (human)
CHOLESTANE SERIES, CHOLESTEROL OXIDES
ROIHL 1276009 Surface studies of membrane lipids and
proteins
CHOLESTANE SERIES, HYDROXYCHOLESTEROLS
** ROIHL 1016013 Origins of atherosclerosis (human)
ROIHL 12740-10 Hypocholesterolemic agents-
Stereochemistry (rats)
ROIHL 1629404 Effectors of cholesterol synthesis (rats)
CHOLESTANE SERIES, LANOSTEROL
ROlHL-21246-02 Roles of cholesterol and its metabolic
regulation (CHO cell mutants)
CHOLESTANE SERIES, SITOSTEROL
R01HL1781805 Metabolism of cholesterol and cholesterol
in man (also rats, monkeys)
CHOLESTANE SERIES, BETA-SITOSTEROL
P50HL14197-07 0006 Supporl for center of research on
arteriosclerosis - Diets and drugs affecting lipid
metabolism (human)
P50HL14237-07 0006 Support for arteriosclerosis center
' Drug treatment of familial hyperbetalipoproteinemia
(human)
ROlHL-22567-01 Validation of a cholesterol absorption
method in man
CHOLESTANE SERIES 5-BETA, COPROSTEROL
P50HL- 19362-02 0009 A/S SCOR -Atherosclerosis in
nonhuman primates • Cholesterol metabolism and
intestinal microflora (baboon)
CHOLESTANES
SEE CHOLESTANE SERIES. CHOLESTANES
5ALPHA-CHOLESTANES
SEE CHOLESTANE SERIES. CHOLESTANES
CHOLESTANOL
SEE CHOLESTANE SERIES, CHOLESTANOL
SBETA-CHOLESTAN-3BETA-OL
SEE CHOLESTANE SERIES 5BETA, COPROSTEROL
CHOLESTEROL
SEE CHOLESTANE SERIES. CHOLESTEROL
CHOLESTEROL ANALOGS
SEE CHOLESTANE SERIES, CHOLESTEROL ANALOGS
CHOLESTEROL ESTER DEFICIENCY, FAMILIAL
SEE MaABOLIC DISORDERS INBORN, LCAT DEFICIENCY
CHOLESTEROL ESTER STORAGE DISEASE
SEE tiiETABOLIC DISORDERS INBORN, LIPID (NEUTRAL)
STORAGE, CHOLESTEROL ESTER STORAGE DISEASE
CHOLESTEROL ESTER AND TRIGLYCERIDE
STORAGE DISEASE WITH ADRENAL
CALCIFICATION
SEE METABOLIC DISORDERS INBORN, LIPID (NEUTRAL)
STORAGE, WOLMAN'S DISEASE
CHOLESTEROL ESTERASE
SEE ESTERASES, CHOLESTEROL ESTERASE
CHOLESTEROL ESTERS
SEE CHOLESTANE SERIES. CHOLESTEROL ESTERS
CHOLESTEROL INHIBITORS
SEE CHOLESTANE SERIES. CHOLESTEROL INHIBITORS
CHOLESTEROL OXIDES
SEE CHOLESTANE SERIES, CHOLESTEROL OXIDES
CHOLESTERYL ESTERS
SEE CHOLESTANE SERIES, CHOLESTEROL ESTERS
IS9
CHOLESTYRAMINE
SI I AMMONIUM UUA1IRNARY, CHOLfSTYRAMINE
CHOLINE
Sit Also PHOSPHOIIPIDS, GLYCEROPHOSPHORIC ESTERS.
GlYCEROPHOSPHORYl CHOI INI
SEE ALSO PHOSPHOIIPIDS. PHOSPHOGIYCI RIDES, LECITHINS
SEE ALSO PHOSPHOLIPIDS, PHOSPHOGLYCLRIDES.
LYSOLECITHIN
SEE ALSO PHOSPHOLIPIDS, PHOSPHOGLYCERIOES,
PLASMALOGFNS
SEE ALSO PHOSPHOLIPIDS, PHOSPHOSPHINGOLIPIOS.
SPHINGOMYELINS
SEE ALSO PHOSPHORYLCHOLINE
** ROIHI 14092 07 Homeostatic regulation of plasma choline
(rats, dogs, chickens)
ROIHL 152 73 06 Metabolism of pulmonary surfactant
(human, rats)
ROIHL 16436 04 Role of calcium and thyroxine in heart
function (rats)
ROIHL 18731 02 RES stimulating materials in
experimental shock (dogs)
** ROIHL 22500 01 Conversion of choline to
phosphatidylcholine in lung (rabbits, pigs)
ROIHL 23003 01 Bulk surface distribution ol cholesteryl
esters
ROIHL 23969 01 Surfactant synthesis by type II cells in
vitro (rats)
CHOLINE, ACETYLCHOLINE
SEE ALSO NEUROPHARMACOLOGICAL AGENTS.
PARASYMPATHOMIMETIC
SEE ALSO NEUROTRANSMITTER RECEPTORS, CHOLINERGIC
RECEPTORS
R01HL05883-18 0001 Reflex control of resistance and
capacitance vessels Naturally occurring vasoactive
substances and the vascular neuroeftectors (dog)
** POlHL-0630818 0039 Mechanisms and therapy of
circulatory disease ANS in regulation of electrophysiology •
Role of cyclic nulceotides (animals)
ROIHL 0772315 Reflex control of vascular capacitance in
shock
R01HL0850815 Cardiac conductivity and automaticity
(human, dogs, rabbits)
POIHL 08682-15 0018 Regulation of the cardiovascular
system - Functional implications of cardiac afferent nerves
(dogs)
POlHL-1034213 0011 The integrated function of
respiration and circulation - Control of respiration 1 -
Peripheral chemoreceptor studies (cats)
POlHL-1034213 0024 The integrated function of
respiration and circulation - Cytochrome P450 and
physiological response to hypoxia (rats)
ROlHL-10951-11 Neural control of the heart (dogs, rats)
POlHL-11310-12 0087 Mechanisms of cardiovascular
disease - Electrophysiology and electropharmacology of the
heart (dogs)
POlHL-1 1678-11 0068 Cardiovascular dynamics and their
control ■ Basic hemodynamics (rats, dogs)
ROlHL-12792-09 Local control of the microcirculation
(hamsters, rats)
ROlHL-13187-09 Central neural control of cardiovascular
function (cats)
ROlHL-1333908 Pharmacology of developing cardiac
tissues (chick embryo)
ROlHL-13349-05 Analysis of activation process in heart
muscle (guinea pigs, rabbits, human)
R01HL-13437-09 Physical and mechanical parameters in
the microcirculation (animals)
R01HL-14092-07 Homeostatic regulation of plasma choline
(rats, dogs, chickens)
P01HL14388-07 0157 Regulation of the circulation in
pathological states - Autoregulation of renal blood flow and
distribution in sodium excretion control
POlHL-14388-07 0211 Regulation of the circulation in
pathological states - Choline acetyltransferase activity
(rats)
R01HL-I4832-06 Myocardial cells-Autonomic and rhythmic
mechanisms (chick embryo, rats)
P01HL15194-07 0004 Pathophysiology of
cardiopulmonary dysfunction - Specialized electrophysiology
fibers-Electrogenic basis of glycosides (mammals)
*♦ ROlHL-15677-06 Autonomic nervous system function in
bronchial asthma (human, guinea pig, rabbit)
ROlHL-15805-06 Cerebral arterial tone and reactivity
(rabbits)
POIHL- 158 3 5-06 0018 Study of muscles related to heart
disease - Pharmacology of excitation coupling in muscle
(frog, barnacles)
ROlHL-15958-06 X-ray diffraction analysis of thrombin
and neurotoxin
ROlHL-15985-06 Metabolic and hormonal control of
cardiac contraction
P01HL-16n7-05 0003 Ion movements and membranes in
cardiovascular control - Fast kinetic study of calcium
membrane interactions
POlHL-161 17-05 0006 Ion movements and membranes in
cardiovascular control - Neuroreceptors and cellular
excitation (fish)
ROlHL-16236-04 Detailed characteristics of coronary blood
flow (horses, dogs, calves)
ROIHL 16318-21 Biochemistry and pharmacology of Na-K
transport
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Onented significantly to above subject.
M Grant has subprojects describing si
See Appendix for investigator's name
CMC
ROIHI 164)6 04 Rolt of cilclum ind lliyisiiiw in heirl
function lrat\)
ROIHI 16/(i0 05 Dynamic control ol coronary blood flow
(dogs)
POIHL 16878 05 0004 Control ol ventilation in health
and disease Neurotrantmilttrt in the respiratory syittm
(cats)
POIHL 1/382 05 000? Chemical mediators ol icuK
pulmonary disorders Chemical mediators ind rnpirilory
mechanics in guinea pigs
*• ROIHL 177990? The presence and signilicance ol heart
acetylcholine (cats)
ROIHL 17847 04 Cardiovascular and renal lunctions ol
marmots
ROIHL 18148 04 Adrenal catecholamine secretion
ROIHL 18718 04 Prostaglandin precursors and vascular
reactivity (dogs)
ROIHL 18795 04 Ischemic arrhythmias Effect of
autonomic tone (dogs, rats, guinea pigs)
ROIHL 18796 04 Experimental cardiac arrhythmias (dogs)
ROIHL 1907603 Vagal control of heart rate A biophysical
model (rabbits)
POIHL 19242 02 0007 Study of vascular smooth muscle
NE release in and reactivity of vascular smooth muscle
(animals)
ROIHL 19653 03 Circulatory system effects ol angiotensin
analogs (rats)
ROIHL 2079302 Phospholipids and cardiac receptor
lunction
ROIHL 20989 01 Pathophysiology of bronchial asthma
(sheep, dogs)
R01HL2115802 Cardiac receptors with vagal Cfiber
afferents (cats)
** ROIHL 2119502 Innervation of the heart Acetylcholine
receptors (frogs)
ROIHL 21314 02 Respiratory tract secretion of ions, water
and mucus (human, dogs)
R23HL2153902 Mechanical properties of isolated small
bronchioles (rabbits)
** ROlHL-21574 01 Automaticity of AV node and its adjacent
tissues (dogs)
POlHL-2158402 0005 Respiratory mechanics in normal
and abnormal states Regulation and behavior of airway
smooth muscle (human, animals)
ROIHL 2179901 Circumventricular sites of pressor action
of angiotensin II (rats)
ROlHL-21860-18 Factors influencing responses to
adrenergic drugs (guinea pigs, rats, cats)
ROlHL-2222301 The cardiopulmonary junction (dogs,
models)
ROIHL 22235-01 Mechanism of cardiac pacemaking
(rabbits)
ROlHL-22426-01 Initiation of the heartbeat -A voltage-
clamp study (bullfrogs, rabbits)
ROlHL-22484-01 Neural control of cardiac conduction and
excitation (dogs)
R23HL 22490-01 Neurotransmitter receptors of cultured
heart cells
R23HL-2266901 Cardiovascular effects from visceral
afferents (dogs)
R23HL-22728-01 Neural control of renin secretion (dogs)
R23HL-22932-01 Effect ol carbon dioxide on local gas
exchange (dogs)
CHOLINE, CARBACHOL
ROlHL-2 1799-01 Circumventricular sites of pressor action
of angiotensin II (rats)
R23HL-22775-01 Muscarinic receptors in the developing
heart (chick embryo)
CHOLINE, METHACHOLINE
ROlHL-07776-15 Sudden death and cardiac arrhythmias
(human, dogs, cats)
R01HL10009-13 Regional lung function in man
P50HL-14153-07 0011 Johns Hopkins Lung Center-
Chronic diseases of airways - Allergy, airways reactivity
and asthma in human ragweed allergy
ROlHL-14844-06 Mucous glycoprotein in human respiratory
epithelium (also wheat)
P01HL-17382-05 0001 Chemical mediators of acute
pulmonary disorders ■ Chemical mediators and respiratory
mechanics in humans
ROlHL-22415-01 Mechanisms responsible tor disease
severity in asthma (human)
ROlHL-23312-01 Hemodynamics and vasoactivity in renal
hypertension (human, dogs)
CHOLINE ACETYLTRANSFERASE
SEE TRANSACYLASES, CHOLINE TRANSACYLASE
CHOLINE DEFICIENCY, NUTRITIONAL
SEE NUTRITIONAL ABNORMALITIES. HYPOVITAMINOSIS B.
CHOLINE DEFICIENCY
CHOLINE ESTERASES
ROlHL-02835-21 Renal transport carrier for organic
compounds (dogs, rats)
POlHL-10342-13 0011 The integrated function of
respiration and circulation - Control of respiration 1-
Peripheral chemoreceptor studies (cats)
R01HL15125-07 Molecular pathology of genetic disorders
in man
(contd)
ipecific research aspects,
and grant number
-f*^v^mrrm,afr^
CHO
CHOLINE ESTERASES, ACETYLCHOLINESTERASE
POlHL-08682-15 0006 Regulation of the cardiovascular
system ■ Cardiovascular studies of mammalian hibernators
(sciuromorpha)
POlHL-08682-15 0011 Regulation of the cardiovascular
system - Histochemistiy and ultrastructure of heart
innervation (dogs, ground squirrels)
ROlHL-18340-04 Electron microscopy of the
juxtaglomerular apparatus (rats)
ROlHL-22226-01 Autonomic nervous elements in the
developing heart (rabbits)
ROlHL-23013-01 Smooth muscle development in vitro
(chick embryo)
CHOLINE PHOSPHATASE
SEE PHOSPHOLIPASE, PHOSPHATIDYLCHOLINE
PHOSPHATIDOHYDROUSE
CHOLINE TRANSACETYLASE
SEE TRANSACYLASES, CHOLINE TRANSACYLASE
CHOLINERGIC AGENTS
SEE NEUROPHARMACOLOGICAL AGENTS,
PARASYMPATHOMIMETIC
CHOLINERGIC BLOCKING AGENTS
SEE NEUROPHARMACOLOGICAL AGENTS,
PARASYMPATHOLYTIC
CHOLINERGIC RECEPTORS
SEE NEUROTRANSMITTER RECEPTORS, CHOLINERGIC
RECEPTORS
CHOLOXIN
SEE THYROID HORMONES. DEXTROTHYROXINE
CHONDROITINASE (HYALURONOGLUCOSIDASE)
SEE CARBOHYDRASES, HYALURONIDASE
CHONDROITIN SULFATE
SEE POLYSACCHARIDES, GLYCOSAMINOGLYCANS,
CHONDROITIN SULFATE
CHONDROITIN SULFATE B
SEE POLYSACCHARIDES, GLYCOSAMINOGLYCANS, DERMATAN
SULFATE
CHONDROMUCOPROTEINS
SEE PROTEOGLYCANS
CHORDOTOMY SURGICAL
SEE NEUROSURGERY, SPINAL CORD LESIONS SURGICAL
CHORIONIC GONADOTROPIN
SEE REPRODUCTIVE HORMONES, GONADOTROPINS
CHORIONIC
CHORIONIC GROWTH HORMONE-PROLACTIN
SEE REPRODUCTIVE HORMONES, CHORIONIC
SOMATOMAMMOTROPIN
CHORIONIC SOMATOMAMMOTROPIN
SEE REPRODUCTIVE HORMONES, CHORIONIC
SOMATOMAMMOfROPIN
CHOROID PLEXUS
SEE BRAIN, CENTRAL SPACES, CHOROID PLEXUS
CHOROIDAL CIRCULATION
SEE EYE CIRCULATION, RETINAL-CHOROIDAL CIRCULATION
CHOROIDAL DISORDERS (GENERAL)
SEE EYE DISORDERS, RETINA AND CHOROID DISORDERS
(GENERAL)
CHRISTMAS DISEASE
SEE BLOOD COAGULATION DISORDERS, CHRISTMAS DISEASE
CHRISTMAS FACTOR
SEE BLOOD COAGULATION, FACTOR IX
CHROMAFFIN SYSTEM
SEE NERVOUS SYSTEM, PARAGANGLIA
CHROMAFFINOMA
SEE NEOPLASMS OF NERVOUS SYSTEM, PARAGANGLIA
NEOPUSMS, PHEOCHROMOCYTOMA
CHROMAFFINOMA, ENTEROCHROMAFFIN
SEE NEOPLASMS OF NERVOUS SYSTEM, CARCINOID
CHROMATIN
SEE GENETICS, CHROMOSOMES, CHROMATIN
CHROMATOGRAPHY
SEE PHYSICAL SEPARATION, CHROMATOGRAPHY*
CHROMATOPHORES
SEE PIGMENTATION, CHROMATOPHORES
CHROMIUM (COMPOUNDS)
SEE METALS. HEAVY METALS, CHROMIUM
CHROMIUM RADIOISOTOPES (51)
SEE RADIOISOTOPES. CHROMIUM
CHROMOPHORE (GROUP), CHEMISTRY
SEE OPTICS, CHROMOPHORE*
160
CHROMOSOME ABNORMALITIES
SEE GENETIC DISORDERS. CHROMOSOME ABNORMALITIES
CHROMOSOME DELETION
SEE GENETICS, MUTATION, CHROMOSOME MUTATION,
DELETION
CHROMOSOME NUMBER ABNORMALITIES
SEE GENETIC DISORDERS. CHROMOSOME ABNORMALITIES
CHROMOSOMES
SEE GENETICS. CHROMOSOMES
CHRONIC DISEASES (DISORDERS)
SEE DISEASES. CHRONIC (GENERAL)
CHRONIC LEUKEMIA
SEE NEOPLASMS OF BLOOD AND RE SYSTEM. LEUKEMIA
CHRONIC
CHRONIC NONSPECIFIC LUNG DISEASE
SEE RESPIRATORY DISORDERS. BRONCHITIS CHRONIC AND
EMPHYSEMA
CHRONIC TREATMENT, DRUGS
SEE DOSAGE AND ROUTE. RATE AND DURATION OF
ADMINISTRATION
CHYLOMICRONS
SEE LIPIDS. CHYLOMICRONS
CHYLOPERITONEUM
SEE BODY CAVITY DISORDERS. PERITONEAL EFFUSIONS.
ASCITES
CHYMOTRYPSIN
SEE PROTEASES AND PEPTIDASES. CHYMOTRYPSIN
CHYMOTRYPSIN B
SEE PROTEASES AND PEPTIDASES. CHYMOTRYPSIN
CIGARETTE SMOKING
SEE PSYCHOLOGY. HABITS. SMOKING
CIGARETTES
SEE CONSUMER PRODUCTS. TOBACCO AND TOBACCO
PRODUCTS
CIGAR SMOKING
SEE PSYCHOLOGY. HABITS. SMOKING
CIGARS
SEE CONSUMER PRODUCTS. TOBACCO AND TOBACCO
PRODUCTS
CILIA
SEE CELL COMPONENTS. CILIA
CILIARY MOVEMENT
SEE CELL COMPONENTS. CILIARY MOVEMENT
CILIOINHIBITORY TEST
SEE DIAGNOSTIC TESTS. CYTODIAGNOSIS. CILIOINHIBITORY
TEST*
CINEANGIOCARDIOGRAPHY
SEE HEART VISUALIZATION. CINEANGIOCARDIOGRAPHY*
CINEFLUOROGRAPHY
SEE RADIOGRAPHY. CINEFLUOROGRAPHY*
CINEMATOGRAPHY
SEE OPTICS. PHOTOGRAPHY. CINEMATOGRAPHY*
CINEMICROGRAPHY
SEE OPTICS. PHOTOGRAPHY. CINEMICROGRAPHY*
CIRCADIAN RHYTHMS
SEE BIOPERIODICITY. CIRCADIAN RHYTHMS
CIRCULAR DICHROISM
SEE OPTICS. DICHROISM CIRCULAR*
CIRCULAR DNA
SEE NUCLEIC ACIDS, DNA CIRCULAR
CIRCULATION
SEE ADRENAL CIRCULATION
SEE CARDIOVASCULAR FUNCTION, BLOOD CIRCULATION
DYNAMICS (GENERAL)
SEE CARDIOVASCULAR SYSTEM
SEE CEREBROVASCULAR SYSTEM, BRAIN CIRCULATION
SEE CEREBROVASCULAR SYSTEM, CEREBRAL CIRCULATION
SEE EYE CIRCULATION
SEE GASTROINTESTINAL CIRCULATION
SEE HEART CIRCULATION
SEE KIDNEY CIRCUUTION
SEE LIVER CIRCULATION
SEE PREGNANCY CIRCULATION
SEE RESPIRATORY CIRCULATION
SEE SKELETAL SYSTEM CIRCULATION
SEE SKIN CIRCUUTION
CIRCULATION TIME
SEE CARDIOVASCULAR FUNCTION, BLOOD CIRCULATION TIME
CIRCULATORY ASSIST
SEE CARDIOVASCULAR SURGERY, CIRCULATORY ASSIST
CLI
CISCLOMIPHENE
SEE STILBENES, CLOMIPHENE
CIS-TRANS ISOMERIZATION
SEE CHEMICAL STRUCTURE, ISOMERS. CIS-TRANS
ISOMERIZATION
CISTRONS
SEE GENETICS, GENES
CITIES
SEE SOCIOENVIRONMENT. URBAN AREAS
CITRATE CONDENSING ENZYME
SEE OXOACID-LYASES. CITRATE (SI) SYNTHASE
CITRATE OXALOACETATE LYASE (COA-
ACETYIATING)
SEE OXOACID-LYASES. CITRATE (SI) SYNTHASE
CITRATE (SI) SYNTHASE
SEE OXOACID-LYASES. CITRATE (SI) SYNTHASE
CITRATES
SEE TRICARBOXYLIC ACIDS, CITRATES
CITRIC ACID
SEE TRICARBOXYLIC ACIDS, CITRATES
CITRIC ACID CYCLE
SEE TRICARBOXYLIC ACIDS, KREBS CYCLE
CLASSIFICATION (GENERAL)
SEE INFORMATION AND COMMUNICATION. CLASSIFICATION
(GENERAL)
CLEARINGHOUSES
SEE INFORMATION SYSTEMS (INCL BANKS AND CENTERS)
CLEAVAGE
SEE CHEMICAL BONOS. BOND CLEAVAGE
CLIMATE
SEE ENVIRONMENT. CLIMATE
CLIMATE CHAMBER CONTROLLED
SEE ENVIRONMENTAL CHAMBER CONTROLLED
CLIMATRON
SEE ENVIRONMENTAL CHAMBER CONTROUED
CLINICAL CHEMISTRY
SEE CHEMISTRY. CLINICAL
CLINICAL DATA COMPUTER PROCESSING
SEE BIOMEDICAL SYSTEMS AUTOMATED. COMPUTER
PROCESSING OF CLINICAL DATA
CLINICAL RESEARCH CENTERS
M POlHL-06314-17 Immunologic mechanisms in
cardiovascular disease
M P50HL-14138-05 Center for research on atherosclerosis
M P50HL-14141-05 SCOR for atherosclerosis in childhood
M P50HL-14218-07 Pulmonary SCOR-Newborn lung center
POlHL-1438807 9004 Regulation of the circulation in
pathological states - Core biostatistics unit
M P60HL-15158-07 Comprehensive sickle cell center
M P60HL-15169-05 Support for center for sickle cell disease
M POlHL-15265-05 Program on surgical control of the
hyperlipidemias
** P01HL15265-05 0013 Program on surgical control of the
hyperlipidemias - Clinical center ■ Minnesota
** POlHL-15265-05 0014 Program on surgical control of the
hyperlipidemias - Arkansas clinical center
M P50HL-17648-04 Study of ischemic heart disease
NOlHV-2291711 Lipid research clinic (human)
NOlHV-32933-07 Hypertension detection and follow-up
program central laboratory (human)
** NOlHV-42929-08 Risk factor intervention trial for the
prevention of CHD (human)
** NOlHV-42930-09 Risk factor intervention trial for the
prevention of CHD (human)
** NOlHV-42931-07 Risk factor intervention trail for the
prevention of CHD (men)
CLINICAL TRIALS REVIEW COMMITTEE
** ROlHL-04697-17 International heart disease epidemiology
(human)
** ROlHL-08888-12 Cooperative study of drugs and coronary
heart disease (men)
** ROlHL-08892-10 Cooperative study of drugs and coronary
heart disease
** ROlHL-09474-11 Natural history-congenital heart defects-
Joint study (human)
** ROlHL-09476-10 Natural history, congenital heart defects-
Joint study
** ROlHL-10445-09 Cooperative study of drugs and coronary
heart disease (men)
** ROlHL-10705-09 Cooperative study of drugs and coronary
heart disease (men)
** ROlHL-10711-12 Cooperative study of treatment of
hypertension (human)
** ROlHL-10718-10 Natural history of congenital heart
defects -Joint study (human)
** ROlHL-11372-08 Cooperative study of drugs and coronary
heart disease (men)
(contd)
•Excludes routine methodology OR covers only general projects which preclude
•*Oriented significantly to above subject-
indexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
cu
161
COM
A prospective study-Blood pressure in
Higli blood pressure In the young
KOIHl 12S4; 0/ Natural history, conienltil heitl detects
loint study (liumen)
ROIHI 16908 04 Myocnrdiel function, risk laclois and
future CHO (men)
ROIHI 1690904 Myocardial lunction. risk lartors and
lutuie CHD (men)
ROIHI I98S803 UMMC Blood pressure precursors and
conserjuences (tiumani
ROIHL 198^9 03 Epidemioloiica! studies, precursors ot
hypertension (human)
M ROIHL 19864 03 Blood pressure ot children and young
adults
** ROIHI 1986903 Antecedents ol adolescent hypertension
(human)
*• ROIHL 198?0 03 Hypertensive progeny Physical and
humoral precursor search
" ROIHL 19922 03 Childhood determinants ol blood pressure
'* ROIHL 1992903 High blood pressure in the young.
prevalence and precursors (human)
*• ROIHI 1993003
newborn twins
•* ROIHL 1995603
(human)
" ROIHL 1996203 High blood pressure in young people in
Tecum seh
** ROIHL'1998402 Blood pressure and immunogenetic
factors in the young (human)
** ROlHL-2000503 Factors m blood pressure levels of
children
** ROIHL 20034 03 Hypertension -Psychophysiologic and
genetic precursors (human)
" ROlHL-20159-03 Genetic epidemiology of precursors of
hypertension (human)
** ROlHL-20244-02 he impact ot hypertension information
** ROlHL-2024501 The impact of hypertension information
** ROIHL 20247-01 The impact of hypertension information
** ROlHL-20248-01 The impact of hypertension information
** RO1HL-20374-03 Myocardial function- Risk factors and
future CHD (human)
•* ROlHL-22298-02 Origins of hypertension (human)
** R01HL-23194-02 Genetics of hypertension and associated
variables (human)
CUNICS (GENERAL)
SEE HEALTH CARE FACILITIES. OUTPATIENT FACILITIES
CUNICS (HOSPITAL)
SEE HOSPITALS. OUTPATIENT FACILITIES
CLOHBRATE
SEE PHENOXYCARBOXYUTES. CLOFIBRATE
CLOMIPHENE
SEE STILBENES. CLOMIPHENE
CLONE CELLS
SEE TISSUE (CELL) CULTURE, CLONE CELLS*
CLONIDINE
SEE IMIDAZOLES. CATAPRES
CLOT DESTRUCTION
SEE BLOOD COAGUUTION, FIBRINOLYSIS
CLOT FILTERS
SEE BLOOD TREATMENT. BLOOD FILTERS
CLOT RETRACTING FACTOR
SEE BLOOD COAGUUTION. THROMBOSTHENIN
CLOT RETRACTION
SEE BLOOD COAGULATION. CLOT RETRACTION
CLOTTING FACTORS (GENERAL)
SEE BLOOD COAGUUTION. CLOHING FACTORS (GENERAL)
CNS CIRCULATION
SEE CEREBROVASCUUR SYSTEM
SEE CEREBROVASCUUR SYSTEM. BRAIN CIRCUUTION
COAGULANT DRUGS
SEE BLOOD COAGUUTION. HEMOSTATICS
COAGULATION
SEE BLOOD COAGUUTION
SEE PROTEINS COAGUUTION
COALESCENCE
SEE PHYSICAL PROPERTIES, COALESCENCE
COARCTATION OF THE AORTA
SEE CAROIOVASCUUR DISORDERS. AORTA OBSTRUCTIONS,
AORTA COARCTATION
COBALT (COMPOUNDS)
SEE METALS, HEAVY METALS, COBALT
COBOGLOBINS
SEE PORPHYROPROTEINS. COBOGLOBINS
COCAINE
SEE TR(}I>ANES. COCAINE
COCCI, GRAM-NEGATIVE
SEE BACTERIA. GRAM-NEGATIVE*
COCHLEA
SEE EAR. UBYRINTH, COCHLEA
COCHLEAR MICROPHONICS
SI I lAH HIAKINC, CdCHllAH MICROPHUNICS
CO-CULTIVATION (MIXED CELL CULTURES)
StI IISSUI (Clin CUIIUHI, MIX(I) CUIIUHIS
CODING (BIOLOGICAL)
Sil INIORMAIION PROCrsSING AND CONTROL (BIOLOGICAL)
CODING (GENETIC)
SIf CrNlIICS, CfNlIIC CODING
CODING (NEURAL)
SFf INFORMATION PRQCfSSING AND CONTROL (NFURAL)
CODING AND INDEXING
see INFORMATION SYSTEMS. INDEXING
CODON
SEE GENETICS. GENETIC COOING
COE VIRUS (COXSACKIE A-21)
SEE VIRUSES. PICORNAVIRUSES. COXSACKIE VIRUSES
COELENTERATES, ANTHOZOA*
" ROIHL 15991 Ob Evaluation ot heart stimulants in sea
anemones
COELOM
SEE BODY CAVITY DISORDERS. PERITONEAL
COENZYME I
SEE PYRIDINE NUCLEOTIDES. NICOTINAMIDE RIBOTIDES.
NAD(H2)
COENZYME A
SEE COENZYMES. COENZYME A
COENZYME A TRANSFERASES
SEE TRANSSULFURASES. COENZYME A TRANSFERASES
COENZYMES
SEE ALSO AMINO ACIDS. CREATINE PHOSPHATE
SEE ALSO FUVIN NUCLEOTIDES. RIBOFUVIN NUCLEOTIDES,
FAD
SEE ALSO FOLIC ACID
SEE ALSO HEMOPROTEINS, CYTOCHROME
SEE ALSO NUCLEOSIDES
SEE ALSO NUCLEOTIDES
SEE ALSO PEPTIDES. GLUTATHIONE
SEE ALSO PYRIDINE NUCLEOTIDES. NICOTINAMIDE RIBOTIDES.
NAD(H2)
SEE ALSO VITAMIN B. BIOTIN
SEE ALSO VITAMIN B. LIPOIC ACID
SEE ALSO VITAMIN C
SEE ALSO VITAMINS METABOLISM
ROIHL 13035-08 Heart mitochondrial malate
dehydrogenase regulation
R01HL-18089-04 Fatty acid metabolism in heart and its
regulation (swine, rats)
ROlHL-21912-01 Biosynthesis of lipoic acid and
atherosclerosis (birds, chick embryos)
COENZYMES, COENZYME A
ROlHL-02477-23 Biosynthesis and function of lipids
(microorganisms, rats)
POlHL-06285-18 0207 Cardiovascular-respiratory
physiology and biochemistry - Feedback control of
cholesterol synthesis in non-hepatic tissues (animals)
ROlHL-13028-09 Regulation of myocardial fatty acid
metabolism (rats)
COENZYMES, COENZYME A, ACETYL-COA
ROlHL-096 10-14 Control of cholesterol metabolism-Bile
acid transport
R01HL-14730-07 Fatty acid beta-oxidation in normal and
ischemic hearts (rabbits)
R01HL-20909-02 Clofibrate-enhanced lipid oxidation by
peroxisomes (rats)
COENZYMES, COENZYME A, ACYL-COA
ROlHL-03734-18 Metabolism of arterial tissue in
atherosclerosis (rabbits)
ROlHL-13028-09 Regulation of myocardial fatty acid
metabolism (rats)
ROlHL-15681-06 Coronary flow studies of partially
obstructed vessels (dogs)
ROlHL-17736-04 Metabolic change during cardiac
ischemia (rats, dogs)
P01HL-19242-02 0002 Study of vascular smooth muscle -
Vascular smooth muscle response to serum lipoproteins
(rats)
ROlHL-20909-02 Clofibrate-enhanced lipid oxidation by
peroxisomes (rats)
P01HL-20948-02 0001 Molecular basis of cholesterol
metabolism - Biochemical and ultrastructural
characterization of LDL in human fibroblasts
ROlHL-21209 02 Alterations of metabolism in ischemic
myocardium (swine)
ROlHL-2316101 0001 Biology of myocardial ischemia -
Mitochondrial lipid metabolism and cardiac ischemia (rat.
dog)
R01HL-23166-01 Pathology of mitochondria in ischemic
myocardium (rats, cattle)
COFACTORS, COENZYMES
SEE COENZYMES
COFFEE
Ml lOQD. BEVCRACrS. COFFIF
COGNITION
SI I l",YCHOIOCY. COGNITION
COGNITIVE CONTROL OF VISCERAL RESPONSES
SM l",Y(.H()ll)(,Y, (.ONhlllONINi. AIII'K.I t<l'. ANlJlNIIRNAl
(,ONIR(JI
COLCHICINE
SFi AIKAIOIOS. COLCHICINt
COLD
SFF TFMPFRATURf, COlO
COLD AGGLUTININ POSITIVE PNEUMONIA
SEE RESPIRATORY OlSORDfRS. PNtUMONIA MfCOPlASMAl
(PPLO)
COLD CLIMATE
SEE ENVIRONMENT, CLIMATE, COLD
COLD PRECIPITABLE FIBRINOGEN
SEE BLOOD COAGUUTION, CRYOFIBRINOGEN
COLD STRESS
SEE ENVIRONMENT, STRESS, COLD INDUCED
COLESTIPOL
SEE CHOLESTANE SERIES, CHOLESTEROL INHIBITORS.
COLESTIPOL
COLLABORATIVE STUDY
SEE COOPERATIVE STUDY
COLLAGEN
SEE ALBUMINOIDS. COLUGEN
COLLAGEN DISEASES
SEE CONNECTIVE TISSUE DISORDERS. COLLAGEN DISEASES
COLLAGENASE
SEE PROTEASES AND PEPTIDASES. COLLAGENASE
COLLATERAL CIRCULATION
SEE CAROIOVASCUUR SYSTEM. BLOOD SUPPLY. COLUTERAL
CIRCUUTION
COLLATERAL RESPIRATION
SEE RESPIRATORY SYSTEM. COLUTERAL RESPIRATION
COLLEGES
SEE EDUCATION. UNIVERSITIES
COLLICULUS INFERIOR
SEE BRAIN. MESENCEPHALON. COLLICULUS INFERIOR
COLLOIDS
SEE PHYSICAL PROPERTIES. COLLOIDS. COLLOIDAL STATE
COLO BUS
SEE MAMMALS. PRIMATES. MONKEYS AND APES
(ANTHROPOIDS. NON-HUMAN). OLD WORLD MONKEYS
(CATARRHINES)*
COLOMBIAN ARROW POISON
(BATRACHOTOXIN)
SEE TOXICOLOGY. ANIMAL POISONS. BATRACHOTOXIN
COLON
SEE GASTROINTESTINAL SYSTEM. INTESTINES. URGE
INTESTINE. COLON
COLOR VISION
SEE EYE. VISION. COLOR VISION
COLYONES
SEE CELL GROWTH REGUUTION. CHALONES
COMBINATION CHEMOTHERAPY
SEE DRUGS. CHEMOTHERAPY. DRUGS COMBINATION
COMMUNICABLE DISEASE CONTROL
SEE ALSO IMMUNITY. IMMUNIZATION (IMMUNOTHERAPY)
** ROlHL-19818-02 Endocarditis on prosthetic heart valves
(rabbits, human)
ROlHL-20 170-02 Pulmonary infection in splenectomized
animals (mice)
ROlHL-21632-02 Development of a transcutaneous power
transfer system (cattle)
ROlHL-22520-01 Pulmonary vascular response to group B
Streptococci (human, mammals)
COMMUNICABLE DISEASE CONTROL AGENTS
SEE ALSO ANTIBIOTICS
SEE ALSO COMMUNICABLE DISEASES CHEMOTHERAPY
SEE ,1S0 IMMUNOLOGICAL PREPARATIONS
(GENERADdNCLUDING CERTIFICATION AND
STANDARDIZATION)
SEE ALSO PESTICIDES
ROlHL-07502-13 Phytochemistry of the genus thalictrum
(dogs, plants)
COMMUNICABLE DISEASE CONTROL AGENTS,
ANTIBACTERIAL
SEE ALSO ANTIBIOTICS
ROlHL-17818-05 Metabolism of cholesterol and cholesterol
in man (also rats, monkeys)
(contd)
*Exdudes routine methodology OR covers only general projects which preclude indexing at the specific level.
•"Oriented significanthf to above subject
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
COM
COMMUNICABLE DISEASE CONTROL AGENTS,
ANTIFUNGAL
ROlHL-07502-13
(dogs, plants)
ROlHL-20675-02
ROlHL-22532-01
(rats, mice, yeast)
Phytochemistiy of the genus thalictrum
Alveolar macrophage function in man
Inhibitors of cholesterol biosynthesis
COMMUNICABLE DISEASE CONTROL AGENTS,
ANTIMALARIALS
ROlHL-187 18-04 Prostaglandin precursors and vascular
reactivity (dogs)
COMMUNICABLE DISEASE CONTROL AGENTS,
ANTIVIRAL
SEE ALSO IMMUNOLOGY. INTERFERON
SEE ALSO VACCINES, VIRAL VACCINES (GENERAL)
ROlHL-1666006 Phospholipid-cholesterol and
phospholipid-protein interactions
COMMUNICABLE DISEASE TRANSMISSION
** NOlHB-62908-07 Maternal to infant transmission of
hepatitis B (human)
** POlHL-09011-15 0018 A research and resource program
in blood ' Hepatitis 6 in normal populations-Epidemiology,
risk factors and transmission
POlHL-09011-15 0020 A research and resource program
in blood Passive immunization in the prevention of
transmission of hepatitis B (human)
COMMUNICABLE DISEASE TRANSMISSION,
CARRIER STATE (COMMUNICABLE DISEASE)
P60HL-23282-01 0004 Comprehensive hospital/community
sickle cell center - Bacterial, viral and mycoplasmal
infections and sickle cell disease complications
COMMUNICABLE DISEASES (GENERAL)
SEE ALSO BACTERIAL DISEASES
SEE ALSO BLOOD TOXICOLOGY. BACTEREMIA-SEPTICEMIA
SEE ALSO CARDIOVASCULAR INFECTIONS
SEE ALSO HOSPITALS INFECTIONS
SEE ALSO IMMUNOLOGY. MICROBIAL
SEE ALSO INJURIES, SURGICAL WOUND INFECTION
SEE ALSO MICROORGANISMS VIRULENCE
SEE ALSO NEOPLASMS, CANCER COMPLICATIONS OF.
INFECTIONS
SEE ALSO RESPIRATORY INFECTIONS
SEE ALSO VIRUS DISEASES
NOlHB-52970-02 Collection, function and transfusion of
granulocytes
NOlHB-62973-05 Collection, function and transfusion of
granulocytes
COMMUNICABLE DISEASES, INFECTIONS,
SECONDARY
SEE ALSO NEOPLASMS. CANCER COMPLICATIONS OF,
INFECTIONS
POlHL-06370-17 0016 Cardiopulmonary and renal
pathology research center • Endocarditis with pulmonary
artery catheters (dogs)
** ROlHL-20002-03 Pulmonary complications of viral
infections (children)
ROlHL-20314-02 Host defense against S pheumoniae in
sickle cell disease (human)
R23HL-21212-02 Alveolar macrophage function in
Pseudomonas infection (dgs)
COMMUNICABLE DISEASES CHEMOTHERAPY
SEE ALSO COMMUNICABLE DISEASE CONTROL AGENTS
" P60HL-1599606 0003 Cincinnati comprehensive sickle
cell center ■ Prophylactic penicillin in treatment of sickle
cell anemia (human)
ROlHL-22520-01 Pulmonary vascular response to group B
Streptococci (human, mammals)
COMMUNICABLE DISEASES DIAGNOSIS*
R01HL13885-08 0006 Cystic fibrosis and pulmonary
disease ■ Cell mediated immunity and Pseudomonas
infections in cystic fibrosis (human)
ROlHL-1388508 0007 Cystic fibrosis and pulmonary
disease - Alveolar macrophage defense mechanism
(human, rabbits)
ROlHL-13885-08 0008 Cystic fibrosis and pulmonary
disease - Pseudomonas specific activation of alveolar
macrophages (human, rabbits)
ROlHL-22838-01 Posttransfusion hepatitis in ne«»born
children
COMMUNICATION (GENERAL)
SEE INFORMATION AND COMMUNICATION (GENERAL)
COMMUNICATIVE SCIENCES STUDY SECTION
** ROIHL 19975-02 Laryngeal biomechanics in pulmonary
therapy (primates)
COMMUNITY HEALTH SERVICES
SEE HEALTH CARE SERVICES, COMMUNITY HEALTH SERVICES
COMMUNITY MENTAL HEALTH CENTERS
SEE MENTAL HEALTH SERVICES, COMMUNITY MENTAL
HEALTH SERVICES
COMMUNITY MENTAL HEALTH SERVICES
SEE MENTAL HEALTH SERVICES, COMMUNITY MENTAL
HEALTH SERVICES
162
COMPENSATORY TRACKING
SEE PSYCHOMOTOR FUNCTION, TRACKING TASK
COMPETITION
SEE PSYCHOLOGY SOCIAL. COMPETITION
COMPLEMENT
SEE IMMUNOLOGY, COMPLEMENT
COMPLEMENT ESTERASE DEFICIENCY OR
DYSFUNCTION
SEE METABOLIC DISORDERS INBORN, ANGIONEUROTIC
EDEMA (HEREDITARY)
COMPLEMENT INHIBITORS
SEE IMMUNOLOGY, COMPLEMENT INHIBITORS
COMPLEMENTATION
SEE GENETICS, GENES, GENE INTERACTION,
COMPLEMENTATION
COMPLEXES
SEE ENZYME COMPLEXES
SEE ENZYME SUBSTRATE COMPLEX
SEE METAL COMPLEXES
COMPLICATIONS (DISEASE ORIENTED)
SEE DISEASES, COMPLICATIONS
COMPLICATIONS OF CANCER
SEE NEOPLASMS, CANCER COMPLICATIONS OF
COMPLICATIONS OF CANCER, INFECTIONS
SEE NEOPLASMS, CANCER COMPLICATIONS OF, INFECTIONS
COMPREHENSIVE HEALTH CARE
SEE HEALTH CARE SERVICES, PATIENT CARE MANAGEMENT.
COMPREHENSIVE CARE
COMPREHENSIVE HEALTH PLANNING
SEE HEALTH CARE (SERVICES)(RESOURCES) PLANNING,
COMPREHENSIVE
COMPRESSION-DECOMPRESSION,
ATMOSPHERIC PRESSURE
SEE ENVIRONMENT, ATMOSPHERIC PRESSURE.
COMPRESSION-DECOMPRESSION
COMPUTER (GENERAL) INCL COMPUTER DATA
PROCESSING (GENERAL)
SEE ALSO BIOMEDICAL SYSTEMS AUTOMATED
SEE ALSO EDUCATION, PROGRAMMED INSTRUCTION,
TEACHING MACHINES
P50HL-141 36-07 9001 Pulmonary SCOR-Airways
obstructive diseases - Biometrics core
COMPUTER, ARTIFICIAL INTELUGENCE, PATTERN
RECOGNITION AND CONTROL SYSTEMS
SEE ALSO BIOMEDICAL SYSTEMS AUTOMATED, COMPUTER
ASSISTED DIAGNOSIS
SEE ALSO BIOMEDICAL SYSTEMS AUTOMATED, COMPUTER
ASSISTED MEDICAL DECISION MAKING
SEE ALSO BIOMEDICAL SYSTEMS AUTOMATED, COMPUTER
ASSISTED PATIENT CARE
SEE ALSO BIOMEDICAL SYSTEMS AUTOMATED, PATIENT
MONITORING (MONITORING DEVICES)
SEE ALSO COMPUTER SIMULATION
SEE ALSO OPTICS, IMAGE PROCESSING ANALYSIS AND
DISPLAY*
POlHL-04664-18 0003 Cardiovascular and lung dynamics
- X-ray projection image videometry (human, dogs)
POlHL-04664-18 0009 Cardiovascular and lung dynamics
- Biological signal and image processing techniques (dogs)
** POlHL-04664-18 0010 Cardiovascular and lung dynamics
- Left ventricular dynamics (human)
POlHL-07293-17 0042 Non-invasive cardiovascular
measurements - Ventricular imaging software (human)
ROlHL-07575-15 Analysis of time-coherent cardiovascular
data
R01HL-104 17-12 Multiple systems in electrocardiography
(human)
ROlHL-13885-08 9001 Cystic fibrosis and pulmonary
disease - Pulmonary function core facility (infants,
children)
ROlHL-13885-08 9002 Cystic fibrosis and pulmonary
disease - Computer core facility (human)
ROlHL-16908-04 Myocardial function, risk factors and
future CHD (men)
ROlHL-16909-04 Myocardial function, risk factors and
future CHD (men)
P50HL-17667-04 0030 Study of ischemic heart disease -
Computerized clinical data acquisition and processing
ROlHL-17702-04
excitability
Electro-optical dyes as probes of heart
Normalized body surface potential maps
Computer technology for transaxial
ROlHL-17931-04
(children)
ROlHL-18968-03
tomography
ROlHL-203 74-03 Myocardial function -Risk factors and
future CHD (human)
R23HL-21292-01 Human ventricular activation-Patterns
and mechanisms (human)
ROlHL-21785-01 Left ventricular wall motion analysis
COM
COMPUTER, DATAPHONE
ROlHL-04666-19 Artificially paced hearts -Technology.
physiology (human, dogs)
ROIHL 16791-03 Computer linkage for a dual camera
system
ROlHL-20835-02 Signal analysis of turbulence study in
blood
COMPUTER, DESIGN AND EVALUATION OF
COMPUTERS (INCL. HARDWARE)
P50HL-17667-04 0042 Study of ischemic heart disease -
Core-Central instrumentation and software
COMPUTER, MAN-COMPUTER INTERACTION
POlHL-04664-18 0004 Cardiovascular and lung dynamics
- X-ray cross section imaging of the circulation (dogs)
COMPUTER, ON-LINE COMPUTERS*
SEE ALSO BIOMEDICAL SYSTEMS AUTOMATED, COMPUTER
ASSISTED PATIENT CARE
SEE ALSO BIOMEDICAL SYSTEMS AUTOMATED, PATIENT
MONITORING (MONITORING DEVICES)
SEE ALSO COMPUTER, ARTIFICIAL INTELLIGENCE, PATTERN
RECOGNITION AND CONTROL SYSTEMS
M POlHL-11307-12 Biophysical studies in pediatric
cardiology
** P01HL11307-12 9001 Biophysical studies in pediatric
cardiology - Core support -computer science
** POlHL-1 1307-12 9002 Biophysical studies in pediatric
cardiology - Biomedical engineering
ROlHL-13885-08 9002 Cystic fibrosis and pulmonary
disease - Computer core facility (human)
POlHL-14414-07 9002 Environmental influences on
cardiorespiratory and cellular functions - Core -Computer
facility
ROlHL-15390-12 Regulation of blood flow in the
microcirculation
P60HL-16008-06 0012 VKayne State University
comprehensive sickle cell center - Central data
management -Computer system
P50HL-1 7648-04 0033 Study of ischemic heart disease -
Data management-Electrocardiographic analysis system
P50HL- 17648-04 0034 Study of ischemic heart disease -
Data management-Hemodynamic data
P50HL-17655-04 0012 Study of ischemic heart disease -
DATA management
ROlHL-18144-03 Preprocessor system for cardiograms
(human)
** ROlHL-18338-04 Computer feedback study of cardiac
muscle mechanics (rats)
ROlHL-19460-03 Mechanics of the papillary muscle and
the left ventricle (cats, rabbits)
R23HL-21 168-01 Hypoxemic respiratory failure-Physiologic
evaluation (human, dogs)
ROlHL-2 1846-01 Cardiac failure detection by radiography
and optics (monkeys)
ROlHL-22484-01 Neural control of cardiac conduction and
excitation (dogs)
ROlHL-23983-01 Quantitative radiocardiography (human,
dogs)
COMPUTER, TIME-DEPENDENT COMPUTER DATA
POlHL-07293-17 0046 Non-invasive cardiovascular
measurements - Cardiac scanner signal processors
ROlHL-07575-15 Analysis of time-coherent cardiovascular
data
COMPUTER ANALYSIS*
POlHL-08899-14 0077 Tolerance to respiratory gases in
health and disease - Isobaric gas supersaturation patterns
ROIHL- 13666-06 Pharmacology of genesis of cardiac
rhythmicity (rats, cats)
** P50HL-14138-05 0014 Center for research on
atherosclerosis - Core biostatistics laboratory
ROlHL-16487-05 Computer controlled two dimensional
echocardiography
POlHL-22619-01 9003 Cellular mechanisms of heart
failure - Computer facility core
COMPUTER AND BIOMATHEMATICAL SCIENCES
STUDY SECTION
** ROlHL-07575-15 Analysis of time-coherent cardiovascular
data
** ROlHL-12711-09 Mathematical approach to cardiovascular
mechanics (human, animals)
ROlHL-14651-05
(dogs, rats)
ROlHL-15622-05
dogs)
ROlHL-16580-04
cell disease
R01HL16791-03
system
ROlHL-18144-03
(human)
ROlHL-18968-03
tomography
ROlHL-19824-02
R23HL-21253-01
image analysis
ROlHL-21785-01
R23HL-21855-01
human lung
Mechanical behavior of left ventricle
Computer simulation in cardiology (rats.
Mathematical models for studying sickle-
Computer linkage for a dual camera
Preprocessor system for cardiograms
Computer technology for transaxial
Mass transfer in the microcirculation
Anatomical models in computer-aided
Left ventricular wall motion analysis
Mathematical models of branching in the
(contd)
•Excludes routine methodology OR covers only general projects which preclude I
**Oriented significantly to above subject.
ndexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
COM
COMPUTER ASSISTED DIAGNOSIS
SU HIOMlOICAl SYSIiMS AIMOMAIID. COMPUHR
ASSISIIO DIAGNOSIS
COMPUTER ASSISTED INSTRUCTION
Sn lOUCAIION. COMPIITIR ASSISIII) INSIRIICIION
COMPUTER ASSISTED MEDICAL DECISION
MAKING
SEE BIOMfOICAl SYSTEMS AUTOMAIEO. COMPUTER
ASSISTED MEDICAL DECISION MAKING
COMPUTER ASSISTED PATIENT CARE
SEE BIOMEDICAl SYSTEMS AUTOMATED, COMPUTER
ASSISTED PATIENT CARE
COMPUTER CENTERS
SEE ALSO BIOMEDICAL SYSTEMS AUTOMATED
SEE ALSO STATISTICAL SERVICE AND CENTERS
** P01HL04664 18 OOIS Cardiovascular and lung dynamics
Computer system for the cardiovascular laboratory
POIHL 11310 12 9003 Mechanisms of cardiovascular
disease Core support biophysical sciences
•• POIHL 11310 12 9004 Mechanisms of cardiovascular
disease Core suppoil computer facilities
** POIHL 12373 10 0014 Cardiopulmonary physiology and
pathophysiology Analog digital computation and
simulation facility
** P50HL 1421807 0011 Pulmonary SCOR-Newborn lung
center Administrative and computer core
** P50HL 15389 07 0020 Pulmonary SCOR Hypersensitivity
pneumonitis Computer applications and data analysis
core
•* P01HL1897403 0017 Experimental neurogenic
hypertension program Computer physiology core
** P60HL1917002 0010 Harvard pulmonary SCOR-Chronic
diseases of the airways Computer Core
COMPUTER CONTROL SYSTEMS (GENERAL)
SEE COMPUTER. ARTIFICIAL INTELLIGENCE. PAHERN
RECOGNITION AND CONTROL SYSTEMS
COMPUTER DESIGN
SEE COMPUTER. DESIGN AND EVALUATION OF COMPUTERS
(INCL. HARDWARE)
COMPUTER DIAGNOSIS
SEE BIOMEDICAL SYSTEMS AUTOMATED, COMPUTER
ASSISTED DIAGNOSIS
COMPUTER GRAPHICS
SEE COMPUTER PRINTING GRAPHICS (GENERAL)
COMPUTER HARDWARE
SEE COMPUTER, DESIGN AND EVALUATION OF COMPUTERS
(INCL. HARDWARE)
COMPUTER INFORAAATION RETRIEVAL
SEE INFORMATION SYSTEMS, INFORMATION RETRIEVAL
COMPUTER PATIENT MONITORING
SEE BIOMEDICAL SYSTEMS AUTOMATED, PATIENT
MONITORING (MONfTORING DEVICES)
COMPUTER PATTERN RECOGNITION (OTHER
THAN IMAGE-WAVESHAPE, OR COMPUTER
SIMULATION OR DIAGNOSIS)
SEE COMPUTER, ARTIFICIAL INTELLIGENCE, PATTERN
RECOGNITION AND CONTROL SYSTEMS
COMPUTER PRINTING-GRAPHICS (GENERAL)
SEE ALSO OPTICS, IMAGE PROCESSING ANALYSIS AND
DISPLAY*
POlHL-04664-18 0004 Cardiovascular and lung dynamics
■ X-ray cross section imaging of the circulation (dogs)
POlHL-0466418 0009 Cardiovascular and lung dynamics
- Biological signal and image processing techniques (dogs)
POlHL-07293-17 0042 Non-invasive cardiovascular
measurements ■ Ventricular imaging software (human)
POlHL-0729317 0047 Non-invasive cardiovascular
measurements - Cardiac scanner system software
** POlHL-07293-17 0048 Non-invasive cardiovascular
measurements - Cardiac scanner recording and display
systems component
** POlHL-07293-17 0056 Non-invasive cardiovascular
measurements - Peripheral vascular system softvrare
ROlHL-09831-12 Effect of resistivity variations on
electrocardiogram (human)
POlHL-11307-12 9002 Biophysical studies in pediatric
cardiology - Biomedical engineering
POlHL-11678-11 0017 Cardiovascular dynamics and their
control - Overall control of circulation -Mathematical
analyses
P01HL-I3480-09 0032 Cardiac electrophysiology - Cardiac
activation sequence (dogs)
POlHL-13480-09 0042 Cardiac electrophysiology ■
Computer modeling of arrhythmias
POlHL-13737-07 0025 Assisted circulation - Driving
system based on quantitative criteria (human, dogs)
ROlHL-13885-08 9002 Cystic fibrosis and pulmonary
disease - Computer core facility (human)
ROlHL-16828-04 Gradient and transport of oxygen in
tissue and organs (mammals)
ROlHL-16901-05 Multipolar linkage between heart
geometry and surface (human, dogs)
1*3
P50HI 17646 04 0002 Study ol lichimic h*i(t dlitiu
Core data managemenl
P50HI 17648 04 0037 Study of ischemic heart dljeiie
Data management Statistic) and data files
PbOHl 1/651 04 0033 Ischemic heart disease speclaliied
center of research Core ticllities Computer sciences
P50HL 1/682 04 0009 Study of ischemic heart disease
Computer core unit
ROIHL 18398 04 Mechanisms of delayed and asymetric
ventricular conduction (human, dogs)
POIHL 185/6 03 0002 Thrombosis research program
prolect Molecular basis of librin formation (human, cattle,
lamprey)
ROIHL 18725 03 Light scattering studies of the sickling
process (human)
ROIHL 1896803 Computer technology for transaxial
tomography
POIHL 19/1/02 0044 Response of the lung to injury
Lung sound analysis (human)
ROIHL 20883 02 Fiber geometry in hypertrophy and
cardiomyopathy (human)
POIHL 21016 02 0001 Sickle cell anemia and other
hemoglobinopathies Supramolecular models of Hb S-
Mutational and EM approach
ROIHL 21088 02 Genetic patterns in deaths from Ml and
stroke in Utah
ROIHL 2127801 Abnormal cardiac wall motion viewed
ultrasonically (human, dogs, phantoms)
COMPUTER PROCESSING OF BIOMEDICAL DATA
(GENERAL)
SEE BIOMEDICAL SYSTEMS AUTOMATED, COMPUTER
PROCESSING OF UBORATORY DATA (GENERAL)
COMPUTER PROCESSING OF CLINICAL DATA
SEE BIOMEDICAL SYSTEMS AUTOMATED, COMPUTER
PROCESSING OF CLINICAL DATA
COMPUTER PROCESSING OF LABORATORY
(BIOMEDICAL) DATA (GENERAL)
SEE BIOMEDICAL SYSTEMS AUTOMATED, COMPUTER
PROCESSING OF LABORATORY DATA (GENERAL)
COMPUTER PROGRAAAMING*
** POlHL-07293-17 0047 Non invasive cardiovascular
measurements - Cardiac scanner system software
** POlHL-08805-15 0043 Regulation of ventilation and
pulmonary circulation - Computer core facility
P01HL08899-14 0089 Tolerance to respiratory gases in
health and disease - Decompression by applications of
optimal control theory
P5CHL-14236-05 0010 Prevention of premature
arteriosclerosis - Computer programs
P60HL- 160 08-06 0012 Wayne State University
comprehensive sickle cell center - Central data
management-Computer system
ROIHL-15601-05 Structure and function of blood proteins
(human, cattle)
ROlHL-17091 05 Anesthetics and microvascular response
to hemorrhage (rats)
** P50HL-17646-04 0002 Study of ischemic heart disease ■
Core data management
P50HL-1 7648-04 0032 Study of ischemic heart disease -
Data management-Statistics and data files
P5GHL-17651-04 0033 Ischemic heart disease specialized
center of research - Core facilities-Computer sciences
P50HL-17651-04 0047 Ischemic heart disease specialized
center of research - Clinical core-Automated arrhythmia
monitoring system
P50HL-1 7665-04 0030 Study of ischemic heart disease -
Data management
P50HL-17667-04 0041 Study of ischemic heart disease -
Biophysical sciences core-Data collection and retrieval
P50HL-17667-04 0042 Study of ischemic heart disease -
Core-Central instrumentation and software
P50HL- 176 70-04 0001 Study of ischemic heart disease -
Data management
P5QHL- 176 70-04 0018 Study of ischemic heart disease -
Core electrocardiogram laboratory (human)
P50HL-I7682-04 0009 Study of ischemic heart disease -
Computer core unit
ROlHL-18808-04 0003 Prediction and prevention of
sudden cardiac death - Technical support (computer)
ROlHL-18968-03 Computer technology for transaxial
tomography
P50HL-191 70-02 0010 Harvard pulmonary SCOR-Chronic
diseases of the airways - Computer Core
P50HL-19362-02 0017 A/S SCOR-Atherosclerosis in
nonhuman primates - Core laboratory-Data management,
statistical analysis
** ROlHL-21052-01 Evaluation of a digitalis therapy advisor
ROlHL-21221-02 Clinical antiarrhythmic and
pharmacodynamic studies
ROlHL-222 74-01 Quanfitating in series effects in cardiac
arrhythmias (dogs)
ROlHL-224 17-01 Microprocessors in medical applications
(dogs)
NOlHV-72927-00 Systems for non-invasive detection of
atherosclerotic lesions (human)
NOlHV-72928-04 Develop high resolution ultrasonic
imaging techniques
COMPUTER SIMULATION
SEE ALSO MODELS, MATHEMATICAL
COM
NOIHI 01486 2J Uuintilalivt study of f <••«• maihariitm-.
(human rahbitt, dogs, chickant)
POIHI 04664 IH 0001 Cardiovatcular and lung dynimict
X ray pruinition image videodaniilomalry (dogil
POIHI 041,64 IH 0002 Cardiovatcular and lung dynamKi
X ray trots section imaging of organs (dogs)
POIHI 0/293 1/ 0042 Non invasive cardiovascular
measurements Ventricular imaging software (human)
POIHI 0/293 1/ 004/ Non invasive cardiovascular
measurements Cardiac scanner system soltHare
ROIHl 0//23 15 Reflen control of vascular capacitance in
shock
POIHL 08899 14 0041 Tolerance to respiratory gases in
health and disease Blood gas transport and brain
circulatory control (human)
POIHL 0901 1 15 001/ A research and resource program
in blood Operations research laboratory
ROIHL 09921 13 Mechanisms related to congestive heart
failure (dogs, human, rat)
ROIHL 10036 13 Biology of red cell antigen antibody
reaction (human)
ROIHL 10330 11 Physiological mechanics of the heart and
arteries (dogs, rabbits, horses)
ROIHL 10417 12 Multiple systems in electrocardiography
(human)
* R01HL1128912 Analysis of stress in pulsatile dynamics
POIHL 11307 12 0002 Biophysical studies in pediatric
cardiology Cardiac extracellular electrophysiology (human,
dog. chimpanzee)
POIHL 11310 12 0058 Mechanisms of cardiovascular
disease Dynamic response to vasodilating agents
postoperatively (human)
•* POIHL 11310 12 0060 Mechanisms of cardiovascular
disease Effect of left atrium on the circulation Simulation
•* POIHL 11310-12 0061 Mechanisms of cardiovascular
disease Computer simulation of transposition of great
arteries in infants
POlHL-11351 12 0003 Cellular and molecular
mechanisms of myocardial function - Mechanical and
electrical properties of cardiac muscle (rabbits)
POlHL-11414 11 0034 Thrombosis and atherosclerosis
program Servo simulation Experimental myocardial
infarction (dogs)
POIHL 1167811 0009 Cardiovascular dynamics and their
control Control of respiration (cat. human)
** POlHL-11678 11 0017 Cardiovascular dynamics and their
control - Overall control of circulation-Mathematical
analyses
POIHLI 1678-11 0036 Cardiovascular dynamics and their
control - Pulmonary capillary dynamics and edema (dogs)
POlHL-11678-11 0051 Cardiovascular dynamics and their
control - Transient glomerular filtration dynamics (dogs)
** POlHL-11678-11 0058 Cardiovascular dynamics and their
control - Overall control of the circulation-Computer
analysis
ROlHL-11907-08 Mechanisms of physiological responses
to exercise (human, dogs)
R01HL11919-08 Pulmonary circulation in surgical heart
disease (human, dogs)
ROlHL-12083-11 Flow field in aorta and its major
branches (dogs, phantom models)
** POlHL-12157-11 0054 Functions and mechanisms of cell
membrane ion transport - Simulation of electrogenic ion
transport in cardiac muscle
ROlHL-12174-11 Ventilation/perfusion distribution in the
lung (human, mammals)
** POlHL-12373-10 0014 Cardiopulmonary physiology and
pathophysiology - Analog digital computation and
simulation facility
** ROlHL-12530-10 Emphysema-Respiratory function in
disease (human, dogs, rats)
** ROlHL-12611-10 Basic and clinical studies of the ST-T
deflection (human, dogs)
ROlHL-12711-09 Mathematical approach to cardiovascular
mechanics (human, animals)
POlHL-12738-10 0044 Physiologic pharmacology and its
clinical applications - Cardioactive drugs and
electrophysiological properties of cardiac cells (sheep)
ROlHL-12820-09 In vitro regulation of prothrombin
activation
** POlHL-13480-09 0042 Cardiac electrophysiology -
Computer modeling of arrhythmias
** POlHL-13737-07 0009 Assisted circulation - Analytical
models
** POlHL-13737-07 0036 Assisted circulation - Assessment
of infarct size from hemodynamic measurements
R01HL13917-20 Secretion and effects of adrenal
hormones (human, rabbits, sheep)
P50HL14147-08 0003 Specialized center of research in
thrombosis - Surface thrombogcnicity and phospholipid
vesicle physical properties
** P50HL-14147-08 0013 Specialized center of research in
thrombosis - Mathematical models of blood coagulation
kinetics
P50HL-14236-05 0001 Prevention of premature
arteriosclerosis - Metabolism and transport of cholesterol
and vitamin A (human, rats)
ROlHL-14306-07 Quantification of artenal pressure control
(dogs)
POlHL-1438807 0214 Regulation of the circulation in
pathological states - Deformation pattern and stress
analysis of the left ventricle
(oontd)
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
''Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
COM
Computer simulation in cardiology (rats,
P01HL14388-07 0215 Regulation of the circulation in
pathological states - Left ventricle model in
pathophysiologic states
P01HLU388-07 0217 Regulation of the circulation in
pathological states • Fluid mechanics of aortic flow (dogs,
human)
ROlHL-14529-07 Systems analysis of baroreflex (dogs)
POlHL-14580-07 0001 Program project in respiratory
mechanics - Micromechanics of the lung (dogs, rats)
R01HI.-1461407 Voltage control of contraction in heart
(sheep)
ROlHL-14645-07 Blood flow measurement by ultrasonic
catheter tip methods (human, dogs)
R01HL-14651-05 Mechanical behavior of left ventricle
(dogs, rats)
RDlHL-1468805 Myocardial assessment by inverse
electrocardiography (monkey)
P60HL15157-07 0011 Comprehensive center for sickle
cell disease - Development of specific anti-sickling
compound (human)
P60HL-15158-07 0014 Comprehensive sickle cell center ■
Mechanism of sickling in human and deer hemoglobins
P60HL15168-07 0009 Comprehensive sickle cell disease
center - Spin label study of sickling (human)
ROlHL-15273-06 Metabolism of pulmonary surfactant
(human, rats)
■ R01HL15622-05
dogs)
ROlHL-15659-05 Dynamic isolation studies of control of
respiration (human)
ROlHL-15676-06 The role of occult myocardial failure in
human shock (human, dogs)
R01HL15698-12 Factors affecting the action of
anticoagulants (rats, human)
R01tfL16052-05 Cardiac glycosides-Mechanism of
inotropic action (dogs)
ROlHL-16076-06 Electrophysiology of fibrillation and
defibrillation (human)
POlHL-161 17-05 0002 Ion movements and membranes in
cardiovascular control ■ Fluorescence and excitation-
contraction coupling in heart (frogs)
ROlHL-16135-05 Mechanisms of cardiac autorhythmicity
(dogs, bats)
ROlHL-16461-05 Late results of valve replacement-
Computer analysis (human)
ROlHL-16580-04 Mathematical models for studying sickle-
cell disease
ROlHL-16606-11 Contraction in heart and other striated
muscles (frogs)
POlHL-16683-04 0001 Function and growth of cardiac
and skeletal muscle - Light chains of the skeletal and
cardiac myosin molecule (rabbits, frogs)
ROlHL-16901-05 Multipolar linkage between heart
geometry and surface (human, dogs)
POlHL-16910-05 0001 Regulation of the peripheral
circulation - Quantitative studies of microcirculatory control
(bats)
P60HL-17269-04 0026 National heart and blood vessel
research and demonstration center - Dynamics of ischemic
heart disease (human, dog)
P60HL-1 7292-04 0008 Vermont Lung Center - Respiratory
physiology-Teaching, learning and auditing problem-solving
skills
ROlHL-17452-04 Depolarization induced cardiac
automaticity (human, animals)
* ROlHL-17517-03 Arterial wall oxygen transport in
atherosclerosis (rabbits, dogs)
ROlHL-17623-05 Initial events in thrombus formation on
surfaces (human, rats)
P50HL-17651-04 0039 Ischemic heart disease specialized
center of research - Measurement and prediction of infarct
size (human, dog)
P50HL-17667-04 0041 Study of ischemic heart disease -
Biophysical sciences core-Data collection and retrieval
P50HL-1 7682-04 0007 Study of ischemic heart disease -
Mechanisms of hypoxemia in myocardial infarction (human)
ROlHL-17711-05 Mechanism of hypoxic regulation of lung
circulation (rats, cats, guinea pigs)
P01HL-I7731-04 0006 Physiological basis of pulmonary
disease - Ventilation-perfusion ratios (human, dogs)
ROlHL-17808-03 Effect of altered oxygen affinity on
oxygen transport (human, rats)
ROlHL-17859-04 Computational methods in cardiac fluid
dynamics
ROlHL-17998-04 Regulatory mechanisms in blood
circulation (dogs)
ROlHL-18080-03 Extrinsic control of intestinal
microcirculation (dogs)
ROlHL-18156-02 Hemodynamics in curved arteries
POlHL-18208-04 0002 Center for the study of blood cell
Theology - Holography of RBC shape (human)
POlHL-18208-04 0005 Center for the study of blood cell
rheology - RBC deformability and capillary flow
interrelations (human, mice)
** ROlHL-18338-04 Computer feedback study of cardiac
muscle mechanics (rats)
ROlHL-18398-04 Mechanisms of delayed and asymetric
ventricular conduction (human, dogs)
ROlHL-18426-04 Regulation of renal hemodynamics (dogs)
P01HL-18576-03 0002 Thrombosis research program
project - Molecular basis of fibrin formation (human, cattle,
lamprey)
164
ROlHL-18968-03 Computer technology for transaxial
tomography
ROlHL-191 39-03 Dispersion of diffusible indicators in the
body (human, cats, dogs)
ROlHL-19647-03 Therapeutic aerosols
POlHL-19737-02 0010 Cellular and molecular aspects of
respiratory physiology - Effects of pulsatile flow and volume
on capillary exchanges (dogs, rats)
ROlHL-19768-02 Recording and analysis of low levels
cardiac signals (human, dogs)
'* ROlHL-19824-02 Mass transfer in the microcirculation
ROlHL-202 19-02 Cryopreservalion of the isolated heart
(rats)
ROlHL-20883-02 Fiber geometry in hypertrophy and
cardiomyopathy (human)
R01HL20898-02 Ultrasonic evaluation in direct arterial
surgery (models, cattle, human)
** POlHL-21016-02 0001 Sickle cell anemia and other
hemoglobinopathies - Supramolecular models of Hb S-
Mutational and EM approach
ROlHL-21052-01 Evaluation of a digitalis therapy advisor
ROlHL-21188-02 Pulsatory water flux and endothelial cell
desquamation
" ROlHL-21283-02 Simulation studies of the ECG in acute
ischemia (and human)
ROlHL-213 19-02 Interpersonal stress and coronary-prone
behavior (human)
ROlHL-21425-02 Servo-simulated compliance changes-A
reversible Ml (dogs)
R23HL-21462-02 Mechanical interactions between ventricle
arteries (dogs)
ROlHL-21518-01 Improvement in regional ventilation-
perfusion resolution (human)
R23HL-21559-01 Oxygen supply and blood flow through
aortic vasa vasorum (dogs)
ROlHL-21672-01 Antiarrhythmic drug action on VMAZ of
cardiac cells
** ROlHL-21684-02 0004 Radionuclide infarct sizing and
therapy evaluation - Image analysis-Kinetics of infarction,
ventricular function (human, animal)
ROlHL-21684-02 0005 Radionuclide infarct sizing and
therapy evaluation - Clinical evaluation of radioisotope
imaging methods for quantifying infarct size
ROlHL-22136-02 Histamine and cardiac adenyl cyclase
ROlHL-221 52-02 Ventricular dysfunction and cardiac
surgery (dogs)
POlHL-22163-01 0002 Surface thrombogenesis-
Mechanisms and prevention - Laser-scattering detection of
microemboli in blood flow (baboons)
ROIHL 22562-02 Mechanism of cardiac action potential
propagation (tunicates)
ROlHL-22844-01 Phrenic nerve pacing-Noninvasive
diaphragm analysis (human, dogs)
R23HL-22932-01 Effect of carbon dioxide on local gas
exchange (dogs)
NOlHV-72927-00 Systems for noninvasive detection of
atherosclerotic lesions (human)
NOlHV-72928-04 Develop high resolution ultrasonic
imaging techniques
COMPUTERIZED ACTASCAN
SEE RADIOGRAPHY, SCANNING, CAT-
COMPUTERIZED AXIAL TOMOGRAPHY
SEE RADIOGRAPHY, SCANNING, CAT*
COMPUTERIZED DATA BANKS
SEE INFORMATION SYSTEMS (INCL BANKS AND CENTERS)
COMPUTERIZED HEALTH RECORDS
SEE HEALTH RECORDS (SYSTEMS) AUTOMATED
COMPUTERIZED INFORMATION SYSTEMS
SEE INFORMATION SYSTEMS (INCL BANKS AND CENTERS)
COMPUTERIZED MEDICAL RECORDS
SEE HEALTH RECORDS (SYSTEMS) AUTOMATED
COMPUTERIZED TRANSAXIAL TOMOGRAPHY
SEE RADIOGRAPHY, SCANNING, CAT*
COMT
SEE TRANSMETHYLASES, CATECHOL 0-METHYL TRANSFERASE
CONALBUMIN
SEE ALBUMINS, CONALBUMIN
CONCANAVALIN A
SEE PLANTS PROTEINS, LECTINS, CONCANAVALIN A
CONDENSATION REACTIONS (CHEMISTRY)
SEE MOLECULAR CONDENSATIONS
CONDITIONING
SEE PSYCHOLOGY, CONDITIONING
CONDITIONING (AUTOGENIC)(BIOFEEDBACK)
SEE PSYCHOLOGY, CONDITIONING, AUTOGENIC AND INTERNAL
CONTROL
CONDITIONING THERAPY (BEHAVIOR)
SEE PSYCHOTHERAPY. BEHAVIOR MODIFICATION
CONDUCTANCE
SEE ELECTRICAL CONDUCTION
CON
CONDUCTION ANESTHESIA
SEE SENSORY DEPRESSION, ANESTHESIA CONDUCTION
CONDUCTION SYSTEM, HEART
SEE HEART, CONDUCTION SYSTEM
CONFERENCES
SEE INFORMATION DISSEMINATION, MEETINGS CONFERENCES
SYMPOSIA
CONFORMATIONS (CHEMISTRY)
SEE CHEMICAL STRUCTURE, STEREOCHEMISTRY,
CONFORMATIONS
CONFORMITY SOCIAL
SEE PSYCHOLOGY SOCIAL, SOCIAL CONFORMITY
CONGENITAL ABNORAAALITIES
SEE ALSO BLOOD AND RE DISORDERS, ANEMIA APLASTIC
CONGENITAL
SEE ALSO BLOOD AND RE DISORDERS. ANEMIA HEMOLYTIC
CONGENITAL (GENERAL)
SEE ALSO GENETIC DISORDERS (SEE ALSO APPROPRIATE
CONGENITAL ABNORMALITIES)
SEE ALSO METABOLIC DISORDERS INBORN
SEE ALSO PREGNANCY DISORDERS, EMBRYO-FETAL
DISORDERS (GENERAL)
SEE ALSO REPRODUCTIVE AND SEX DEVELOPMENT
DISORDERS
•* POlHL-09011-15 0010 A research and resource program
in blood - Chromosome changes in human genetics
ROlHL-15655 05 Blood flow and gas exchange in placenta
and lungs (sheep) rabbits)
ROlHL-17808-03 Effect of altered oxygen affinity on
oxygen transport (human, rats)
CONGENITAL ABNORMALITIES, BRAIN
(GENERAL)
SEE ALSO CONGENITAL ABNORMALITIES, NEUROLOGICAL,
DYSAUTONOMIA fAMILIAL
SEE ALSO MENTAL RETARDATION
ROlHL-09913-13 Cerebral veins -Anatomic and radiologic
correlation (human)
CONGENITAL ABNORMALITIES,
CARDIOVASCULAR DEFECTS
SEE ALSO CONGENITAL ABNORMALITIES. CARDIOVASCULAR
SHUNTS ABNORMAL
SEE ALSO COt<GENITAL ABNORMALITIES. HEART DEFECTS
SEE ALSO CONGENITAL ABNORMALITIES, HEART SEPTAL
DEFECTS
SEE ALSO METABOLIC DISORDERS INBORN, ANGIONEUROTIC
EDEMA (HEREDITARY)
POlHL-06285-18 0136 Cardiovascular-respiratory
physiology and biochemistry - Fetal microcirculation in
utero (rabbits, lambs)
ROlHL-19430-03 Congenital heart malformations and
situs inversus (mice)
ROlHL-20124-02 Coronary risk factors (human)
ROlHL-20132-03 Histogenesis and biochemistry of
embryonic lung (birds)
ROlHL-2 1088-02 Genetic patterns in deaths from Ml and
stroke in Utah
ROlHL-21971-01 Atherosclerotic disease and risk factors
in twins (human)
CONGENITAL ABNORMALITIES,
CARDIOVASCULAR SHUNTS ABNORMAL
SEE ALSO CONGENITAL ABNORMALITIES, HEART SEPTAL
DEFECTS
P01HL-1043613 0001 A multidisciplinary study of
congenital heart disease ■ Assessment of the outlook for
children with congenital heart disease
ROlHL-11919-08 Pulmonary circulation in surgical heart
disease (human, dogs)
CONGENITAL ABNORMALITIES,
CARDIOVASCULAR SHUNTS ABNORMAL,
PATENT DUCTUS
** POlHL-06285-18 0125 Cardiovascular-respiratory
physiology and biochemistry - Ventricular output, foramen
ovale and ductus arteriosus flows (lambs)
** POlHL-06285-18 0130 Cardiovascular-respiratory
physiology and biochemistry - Ductus arteriosus-
Morphological development (human, lambs)
ROlHL-12307-08 Non-surgical treatment of congenital
heart disease (human, dogs)
" P50HL-142 14-07 0026 Newborn lung center for hyaline
membrane disease ■ Hemodynamic studies of HMD-
Prostaglandins production and blockers (lambs)
** P50HL-142 14-07 0030 Newborn lung center for hyaline
membrane disease - Effects of ductal patency-Impedance
cardiography and echocardiography (human)
ROlHL-16656-06 Lett ventricular function in exercise
(dogs)
** ROlHL-17581-03 Patent ductus arteriosus and pulmonary
hypertension (dogs)
ROlHL-1884803 Etiology and development of congenital
heart disease (dogs, cats)
** R01HL-22784-01 Ductus arteriosus closure-An arterial
lesion model (rabbits)
(contd)
•Excludes routine methodology OR covers only general projects which preclude
**Onented significantly to above subject.
indexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
CON
CONOENITAl ABNORMALITIES,
CARDIOVASCULAR SHUNTS ABNORMAL,
VESSELS TRANSPOSITION
ROlNLO/bOb 16 Congenitdl heart dlKlsa (tssiich
ptoiom (human, dogs)
*• POIHI 11310 12 0061 Mechnnisms ol CBidiovasculai
disease Computei sfmulation ol tiansposilion ol great
arteries in infants
" POIHL 11310 1? 0064 Mechanisms ol cardiovascular
disease Ixtiacardiac anatomical correction ot
transposition ot great arteries (puppies)
POIHL 12/38 10 0127 Physiologic pharmacology and its
clinical applications Cardiac electrical activity (human.
animals)
ROIHI 16329 04 Cardiac surgical ellect on heart function
in infants (human)
ROIHL WS7804 Exercise performance in children with
heart disease
ROIHL 1920303 Surgical approach to congenital heart
diseases (dogs, primates)
CONGENITAL ABNORMALITIES, HEART DEFECTS
SEE ALSO CONGENITAL ABNORMALITIES. CARDIOVASCUUR
SHUNTS ABNORMAL. VESSELS TRANSPOSITION
SEE ALSO CONGENITAL ABNORMALITIES, HEART SEPTAL
DEFECTS
** R01HL05694 20 Functional pathology of cardiovascular
disease (human)
** P01HL06285 18 0127 Cardiovascular-respiratory
physiology and hiochemistry Experimental congenital
cardiac lesions in fetal lambs
P01HL06285 18 0129 Cardiovascular-respiratory
physiology and biochemistry - Pulmonary microcirculation in
the fetus and neonate (lambs)
** POlHL-06285 18 0130 Cardiovascular-respiratory
physiology and biochemistry - Ductus arteriosus
Morphological development (human, lambs)
** POlHL-06285-18 0131 Cardiovascular-respiratory
physiology and biochemistry - Fetal heart development and
ventricular outflow obstruction (lambs)
P01HL0628518 0136 Cardiovascular-respiratory
physiology and biochemistry - Fetal microcirculation in
utero (rabbits, lambs)
POlHL-06296-18 0003 Cardiovascular and pulmonary
adaptation to stress - Human exercise studies (human,
dogs)
M POlHL-0729317 Non-invasive cardiovascular
measurements
P01HL07293-17 0043 Non-invasive cardiovascular
measurements - ECHO-Doppler instrumentation for cardiac
measurements (human)
POlHL-07293-17 0059 Non-invasive cardiovascular
measurements - Intracardiac blood flow measurement
(human)
** ROlHL-07605-16 Congenital heart disease research
program (human, dogs)
** ROlHL-09474-11 Natural history-congenital heart defects-
Joint study (human)
** R01HL-09476-10 Natural history, congenital heart defects-
Joint study
M POlHL-10436-13 A multidisciplinary study of congenital
heart disease
** POlHL-10436-13 0001 A multidisciplinary study of
congenital heart disease - Assessment of the outlook for
children with congenital heart disease
POlHL-10436-13 0002 A multidisciplinary study of
congenital heart disease - Myocardial performance,
metabolism and ultrastructure (human, cats, rats)
** POlHL-10436-13 0005 A multidisciplinary study of
congenital heart disease - Pulmonary physiology in
congenital heart disease (human)
POlHL-10436-13 0006 A multidisciplinary study of
congenital heart disease - Ventricular blood pumps and
valves (human, cattle)
** POlHL-10436-13 0008 A multidisciplinary study of
congenital heart disease - Physiologic consequences of
chronic hypoxemia (human)
** POIHL-10436-13 0009 A multidisciplinary study of
congenital heart disease - Pathophysiology and
morphogenesis of congenital heart disease (human)
** POlHL-10436-13 0016 A multidisciplinary study of
congenital heart disease - Genetic studies of congenital
heart disease (human)
** ROlHL-10718-10 Natural history of congenital heart
defects-Joint study (human)
M POlHL-11310-12 Mechanisms of cardiovascular disease
POlHL-1 1310-12 0069 Mechanisms of cardiovascular
disease - Factors affecting mortality and morbidity after
heart surgery (human)
POlHL-11310-12 0070 Mechanisms of cardiovascular
disease - Factors affecting long-term mortality and
morbidity after heart surgery (human)
** POlHL-11310-12 0076 Mechanisms of cardiovascular
disease - Tratment of depressed cardiac output following
heart surgery (children, puppies)
** POlHL-11310-12 0077 Mechanisms of cardiovascular
disease - Abnormalities of rhythm and conduction following
heart surgery (human)
** POlHL-1 1310-12 0079 Mechanisms of cardiovascular
disease - Electrophysiological studies of complete heart
block (human)
US
POIHI 11310 12 0082 Mechanisms ol cardiovascular
disease Myocardial function in adult congenital henil
disease (human)
POIHL 11310 12 0083 Mechanisms ol cardiovascular
disease Ventricular volume and hemodynamics in adult
congenital heart disease
POIHL 11310 12 9001 Mechanisms ot cardiovascular
disease Core support hospital beds
ROIHL 12307 08 Nonsurgical treatment ol congenital
heart disease (human, dogs)
POIHL 123/3 10 0005 Cardiopulmonary physiology and
pathophysiology Characteri/alion ol letal and neonatal
myocardium (human, cats)
ROIHL 12542 0/ Natural history, congenital heart defects
Joint study (human)
Physiologic pharmacology and its
Ventricular function and structure
POIHL 12/38 10 0094
clinical applications
(human, dogs)
POIHL 1438807 0214
pathological states
Regulation of the circulation in
Dclormation pattern and stress
analysis of the left ventricle
POIHL 1438807 0215 Regulation of the circulation in
pathological states Left ventricle model in
pathophysiologic states
ROIHL 1504706 Digital computer analysis ol the
electrocardiogram (human)
ROIHL 15190 07 Physiological basis of arrhythmias and
their therapy (human)
ROlHL-16260-04 Development of clinical cine ultrasound
cardiography
ROlHL-16329-04 Cardiac surgical effect on heart function
in infants (human)
ROlHL-17578-04 Exercise performance in children with
heart disease
ROlHL-17629-03 Developmental aspects of cardiovascular
function (human, cats, rabbits)
ROlHL-17931-04 Normalized body surface potential maps
(children)
ROlHL-17993-04 0009 Ventricular dynamics from
surgically inserted markers - Cardiovascular visualization in
surgery of growing heart (dogs)
ROlHL-18050-04 Mechanisms of cardiovascular
teralogenesis (chick embryo) k embryo)
ROlHL-18328-03 Hemoglobin function and tissue
oxygenation (human, dogs)
R01HL-18398-04 Mechanisms of delayed and asymetric
ventricular conduction (human, dogs)
ROlHL-18824-03 Mechanisms of heart failure in
myopathic hamster
ROIHL- 18848-03 Etiology and development of congenital
heart disease (dogs, cats)
R01HL-I9203-03 Surgical approach to congenital heart
diseases (dogs, primates)
ROlHL-19225-02 0004 Types and mechanims of
pulmonary hypertension - Structural changes in human
pulmonary circulation (human, animals)
ROlHL-19430-03 Congenital heart malformations and
situs inversus (mice)
ROlHL-20037-02 Left ventricular-aortic bypass and
composite prosthesis (sheep, swine, cattle)
ROlHL-20190-02 Pathogenesis of cardiac hypertrophy
(dogs)
ROlHL-20630-03 Development of a pulsed Doppler velocity
detector (human, animals)
ROlHL-20677-02
disease
Radionuclide studies in congenital heart
Intra-aortic balloon pumping (dogs,
Videoroentgenography in congenital heart
Ventricular dysfunction and cardiac
Genetic cardiomyopathies in salamanders
ROlHL-20803-02
lambs, cats)
** ROlHL-21985-01
disease
*• ROlHL-221 52-02
surgery (dogs)
** ROlHL-22550-02
and hamsters
** ROlHL-22963-01 Symbolic logic analysis of congenital
heart disease (human)
ROlHL-23232-01 Effect of hypoxia on PVSM and its
precursor cells
CONGENITAL ABNORMALITIES, HEART DEFECTS,
ASYMMETRIC SEPTAL HYPERTROPHY
ROlHL-16901-05 Multipolar linkage between heart
geometry and surface (human, dogs)
"* ROlHL-206 10-02 Nerve grovrth factor and obstructive
cardiomyopathy (dogs)
CONGENITAL ABNORMALITIES, HEART DEFECTS,
TETRALOGY OF FALLOT
POlHL-10436-13 0001 A multidisciplinary study of
congenital heart disease - Assessment of the outlook for
children with congenital heart disease
POlHL-10436-13 0006 A multidisciplinary study of
congenital heart disease - Ventricular blood pumps and
valves (human, cattle)
ROlHL-16329-04 Cardiac surgical effect on heart function
in infants (human)
ROlHL-17578-04
heart disease
Exercise performance in children with
CON
CONOENITAL ABNORMALITIES, HEART DEFECTS,
V^OLFF-PAHKINSON WHITE SYNDROME
*• I'OIIII 0(, lOH l« 0044 M«(h»ni-.m-. ami Ihoupy ol
(.iiiulalory diiease Echocardiography to datermina iila ol
eclopir. impure lormation (human, dogt)
ROIHI 0/04/ 16 Comparative «ludy of cardiac conduction
system (human, birds, mammals)
ROIHI O/bO'i lb Congnnilal heart diuaM rataarch
prugi^m (human, dogs)
POIHI 1110/ 12 0002 Biophysical itudiei in pediatric
cardiology Cardiac extracellular eleclrophysiology (human,
dog. chimpanzee)
ROIHI 15190 0/ Physiological basis ol arrhythmias and
Iheir therapy (human)
** ROIHI 17931 04 Normalized body surface polanlial mapi
(children)
•• ROIHI 18398 04 Mechanisms of delayed and a-.ymelric
ventricular conduction (human, dogs)
CONGENITAL ABNORMALITIES, HEART SEPTAL
DEFECTS
SEE ALSO CONGENITAL ABNORMALITIES. HEART DEFECTS.
ASYMMETRIC SEPTAL HYPERTROPHY
SEE ALSO CONGENITAL ABNORMALITIES. HEART DEFECTS,
TETRALOGY OF FALLOT
ROIHL 05694 20 Functional pathology of cardiovascular
disease (human)
P01HLO6285 18 0126 Cardiovascular-respiratory
physiology and biochemistry Ventricular output, foramen
ovale and ductus arteriosus flows (lambs)
P01HL07293 17 0043 Noninvasive cardiovascular
measurements ECHO-Doppler instrumentation lor cardiac
measurements (human)
POlHL-07293 17 0051 Non-invasive cardiovascular
measurements Physiologic evaluation of duplex scanner
(dogs)
POlHL-07293 17 0052 Non invasive cardiovascular
measurements Clinical evaluation ol the duplex scanner
(human)
POlHL-07293-17 0059 Noninvasive cardiovascular
measurements - Intracardiac blood flow measurement
(human)
ROlHL-07605-16 Congenital heart disease research
program (human, dogs)
** ROlHL-09474-11 Natural history-congenital heart defects-
Joint study (human)
** ROlHL-09476-10 Natural history, congenital heart defects-
Joint study
ROlHL-09711-13 Instantaneous blood flow in ascending
aorta (human, dogs)
POlHL-10435-13 0001 A multidisciplinary study of
congenital heart disease - Assessment of the outlook for
children with congenital heart disease
" ROlHL-10718-10 Natural history of congenital heart
defects-Joint study (human)
ROlHL-12307-08 Non-surgical treatment of congenital
heart disease (human, dogs)
** ROlHL-12542-07 Natural history, congenital heart defects-
Joint study (human)
" POlHL-12738-10 0131 Physiologic pharmacology and its
clinical applications - Evaluation of intracardiac shunts by
contrast echocardiography (dogs)
ROlHL-16329-04 Cardiac surgical effect on heart function
in infants (human)
** ROlHL-18398-04 Mechanisms of delayed and asymetric
ventricular conduction (human, dogs)
ROlHL-18848-03 Etiology and development of congenital
heart disease (dogs, cats)
** ROlHL-19136-03 Mucopolysaccharide metabolism in
cardiac anomalies (rats)
ROlHL-20132-03 Histogenesis and biochemistry of
embryonic lung (birds)
** R23HL-21203-02 Effect of vasoactive agents on left-to-
right shunts (lambs)
** R01HL22963-01 Symbolic l0(,ic analysis of congenital
heart disease (human)
CONGENITAL ABNORMALITIES, NEUROLOGICAL,
DYSAUTONOMIA FAMILIAL
** ROlHL-17711-05 Mechanism of hypoxic regulation of lung
circulation (rats, cats, guinea pigs)
CONGENITAL ABNORMALITIES, RESPIRATORY
(GENERAL)
POlHL-10436-13 0005 A multidisciplinary study of
congenital heart disease - Pulmonary physiology in
congenital heart disease (human)
ROlHL-15526-05 Respiratory mechanics in children
ROlHL-20132-03 Histogenesis and biochemistry of
embryonic lung (birds)
CONGENITAL ABNORMALITIES, RESPIRATORY
DISTRESS SYNDROME
SEE ALSO RESPIRATORY GAS LEVELS. HYPOXIA NEONATORUM
POlHL-06285-18 0208 Cardiovascular-respiratory
physiology and biochemistry Composition, properties and
turnover of pulmonary surfactant (human, animals)
POlHL-06285-18 0210 Cardiovascular-respiratory
physiology and biochemistry - Physicochemical and
enzymatic studies of lung surfactant (Halobacterium)
ROlHL-10834-09 Fetal and neonatal pulmonary circulation
(goats)
(contd)
•Excludes routine methodology OR covers only general projects which preclude
••Oriented significantly to above subject-
indexing at the specific level.
M Grant has subprojeds describing specific research aspects.
See Appendix for investigator's name and grant number.
CON
166
CON
Pulmonary SCOR-Airways
Pediatric airways obstructive disease
P50HL-14136-07 0017
obstructive diseases -
(human)
P50HL-14187-07 0012 Pulmonaiy SCOR-Chemical
mediators in pulmonary vascular responses • Vasoactive
mediators in pulmonary disease (human, animal)
P50HL-14214-07 Newborn lung center for hyaline
membrane disease
Newborn lung center for hyaline
Pulmonary status of children who had
P50HL-14214-07 0012
membrane disease
HMD as infants
P50HL-14214-07 0013
membrane disease
Newborn lung center tor hyaline
Developmental outcome of children
who had HMD as infants
P50HL 1421407 0015 Newborn lung center for hyaline
membrane disease - Hormone effect on cyclic nucleotide
lipid synthesis in developing lung (animal)
P50HL'14214-07 0020 Newborn lung center for hyaline
membrane disease - Epidermal growth factor effect-Lung
differentiation, maturation (human, rabbit)
P50HL-14214-07 0021 Newborn lung center for hyaline
membrane disease ■ Development of surlactant system-
Surfactant production and release (rat, rabbit)
P50HL-14214-07 0022 Newborn lung center for hyaline
membrane disease Functional integrity of surfactant
system-Hyaline membrane disease (lamb, rat)
P50HL-14214-07 0023 Newborn lung center for hyaline
membrane disease - Regulation of fetal lung maturation-
Vitamin A (rat, rabbit, sheep, human)
P50HL-14214-07 0024 Newborn lung center for hyaline
membrane disease - Synthesis and receptors for ACTH in
fetal lung (human)
P50HL-14214-07 0025 Newborn lung center for hyaline
membrane disease - Pulmonary vascular permeability and
lung water-Hyaline membrane disease (sheep)
P50HL-14214-07 0026 Newborn lung center for hyaline
membrane disease - Hemodynamic studies of HMD-
Prostaglandins production and blockers (lambs)
P50HL14214-07 0027 Newborn lung center for hyaline
membrane disease - Oral-laryngeal chemoreceptors and
respiratory failure in newborns (human, sheep)
P50HL14214-07 0028 Newborn lung center for hyaline
membrane disease - Relationship of trace metals to
respiratory failure (dog, sheep, human)
P50HL-142 14-07 0029 Newborn lung center for hyaline
membrane disease - The diving reflex -Perinatal asphyxia,
pulmonary ischemia and HMD (sheep)
P50HL-14214-07 0030 Newborn lung center for hyaline
membrane disease - Effects of ductal patency-Impedance
cardiography and echocardiography (human)
P50HL-14214-07 0031 Newborn lung center for hyaline
membrane disease - Essential fatty acid deficiency and
HMD (human)
P50HL-14214-07 0032 Newborn lung center for hyaline
membrane disease - Evoked electroencephalographic
potential in infants with HMD (human)
P50HL-14214-07 0033 Newborn lung center for hyaline
membrane disease - Statistical modeling, predictive
classification in clinical management of HMD
P50HL-14214-07 0034 Newborn lung center for hyaline
membrane disease - Core-Newborn intensive care unit
P50HL-14214-07 0035 Newborn lung center for hyaline
membrane disease - Core -Animal care facility
P50HL-14214-07 0036 Newborn lung center for hyaline
membrane disease - Core-Biomedical engineering
P50HL-14214-07 0037 Newborn lung center for hyaline
membrane disease - Core-Histopathology laboratories
P50HL-14218-07 Pulmonary SCOR-Newborn lung center
P50HL-14218-07 0004 Pulmonary SCOR-Newborn lung
center - Metabolism of infants with respiratory distress
syndrome (human)
P5OHL-14218-07 0005 Pulmonary SCOR-Newborn lung
center - Prevention of infection in infants with respiratory
distress (human)
' P50HL-14218-07 0006 Pulmonary SCOR-Newborn lung
center - Biochemical characteristics of the lung in RDS
(human, sheep)
P50HL-14218-07 0011 Pulmonary SCOR-Newborn lung
center - Administrative and computer core
' P50HL-14218-07 0012 Pulmonary SCOR-Newborn lung
center - Longitudinal study of RDS -On-line fetal and
neonatal monitoring (human)
P50HL-14218-07 0013 Pulmonary SCOR-Newborn lung
center - Longitudinal study of RDS-Monitoring fetal P02
and PC02 during labor (human)
P50HL-14218-07 0014 Pulmonary SCOR-Newborn lung
center - Longitudinal study of RDS-Monitoring fetal
breathing movements (human)
' P50HL-14218-07 0015 Pulmonary SCOR-Newborn lung
center - Long term follow-up of infants surviving RDS-
Neurological outcome (human)
' P50HL-14218-07 0017 Pulmonary SCOR-Newborn lung
center - Transvascular fluid exchange, vasoactive mediators
in RDS (sheep, cat)
ROlHL-14663-07 Pulmonary oxygen toxicity in newborn
lung (human, mice)
ROlHL-14692-06 Alpha 1 antitrypsin deficiency and
pulmonary disease (human)
■ ROlHL-14854-07 Lung and tissue mechanics (monkeys,
dogs)
P50HL-15061-07 0013 Response of lung to injury -
Exchange transfusion in infants with respiratory distress
syndrome (human, sheep)
ROlHL-15273-06 Metabolism of pulmonary surfactant
(human, rats)
ROlHL-153 16-07 Lung surfactant system -Control
mechanisms (rats)
R01HL-15430-05 Cardiopulmonary adaptation of newborns
to altitude (human)
R01HL-15526-0S Respiratory mechanics in children
POlHL-16137-05 Alveolar biology
POlHL-16137-05 0013 Alveolar biology - Development and
pathology of surfactant-Formation of alveolar (rabbits,
sheep)
ROlHL-17629-03 Developmental aspects of cardiovascular
function (human, cats, rabbits)
ROlHL-17800-04 Pulmonary reflexes-Central pathways
(cats. dogs, rabbits)
ROlHL-18507-03 Clinical studies of Fletcher factor
(human)
ROIHL 19010-03 Metabolism and cell biology of lung
surfactant system (rabbits, sheep)
P50HL-19185-02 Pulmonary SCOR-Neonatal respiratory
distress syndromes
P50HL-19185-02 0002 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Biochemistry.
ultrastructure-Pulmonary surface active material (human,
animal)
P50HL-19185-02 0003 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Factors affecting formation
and release of pulmonary surfactant in fetal lambs
' P50HL-19185-02 0004 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Fluid and protein transport
in fetal and newborn lung (sheep, rabbits)
' P50HL-19185-02 0005 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Role and mechanism of
glucocorticoids in fetal lung maturation (human, rabbit)
■ P50HL-19185-02 0006 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Evaluation of risk factors
in neonatal respiratory distress (human, sheep)
' P50HL-19185-02 0007 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Sodium bicarbonate and
albumin in resuscitation of preterm infants (human)
' P50HL-19185-02 0009 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Nasal continuous positive
airway pressure in hyaline membrane disease (human)
' P50HL-19185-02 0011 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Complications and
sequelae of neonatal respiratory distress (human)
P50HL-19185-02 0012 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Core microscopy lab
P50HL-19187-02 Pediatric pulmonary SCOR-Hyaline
membrane disease
* P50HL-19187-02 0001 Pediatric pulmonary SCOR-Hyaline
membrane disease - Hyaline membrane disease-Changes
in lung mechanics and gas exchange (monkeys)
* P50HL-19187-02 0002 Pediatric pulmonary SCOR-Hyaline
membrane disease - Hyaline membrane disease-Alterations
in surface active material (monkeys)
* P50HL-19187-02 0003 Pediatric pulmonary SCOR-Hyaline
membrane disease - Hyaline membrane disease-
Ultrastructure studies (monkey)
' P50HL-19187-02 0004 Pediatric pulmonary SCOR-Hyaline
membrane disease - Hyaline membrane disease-Surface
active material, lamellar bodies (mice, rats)
* P50HL-19187-02 0007 Pediatric pulmonary SCOR-Hyaline
membrane disease - Follow-up study-infants with hyaline
membrane disease (human)
P50HL-19187-02 0009 Pediatric pulmonary SCOR-Hyaline
membrane disease - Non-invasive measurement and
monitoring of arterial oxygen tension (dogs, sheep)
* P5aHL-19187-02 0010 Pediatric pulmonary SCOR-Hyaline
membrane disease - Treatment, outcome of HMD-
Continuous positive airway pressure (human, monkey)
* P50HL-19187-02 0011 Pediatric pulmonary SCOR-Hyaline
membrane disease - Effects of hypoxia and hypercapnia on
developing nervous system (monkey, human)
* P50HL-19187-02 0012 Pediatric pulmonary SCOR-Hyaline
membrane disease - Resource requirements, economic
consequence of HMD and recurrent apnea
* P50HL-191 87-02 0013 Pediatric pulmonary SCOR-Hyaline
membrane disease - Research resources core
I P50HL-19190-02 Pulmonary SCOR-Pathophysiology,
management of IRDS
Pulmonary SCOR-Pathophysiology,
Core-Clinical research center
P50HL-19190-02 0001
management of IRDS -
(infants)
P50HL-19190-02 0002
management of IRDS -
dissemination
P50HL-19190-02 0003
management of IRDS
differentiation (rat)
P50HL-19190-02 0004
management of IRDS
turnover (rabbit)
P50HL-191 90-02 0005
management of IRDS
(human, cattle)
P50HL-19190-02 0006
management of IRDS
Pulmonary SCOR-Pathophysiology.
Core-Demonstration and
Pulmonary SCOR-Pathophysiology,
Type II cells-Regulation and
Pulmonary SCOR-Pathophysiology,
Type II cells -Control of protein
Pulmonary SCOR-Pathophysiology,
Glycoproteins in mucous secretions
Pulmonary SCOR-Pathophysiology,
Asphyxia-Respiratory control (dogs)
P50HL-19190-02 0007 Pulmonary SCOR-Pathophysiology,
management of IRDS - Asphyxia-Cerebral metabolism (dog,
rat)
** P50HL-19190-02 0008 Pulmonary SCOR-Pathophysiology,
management of IRDS - Hemodynamics and gas exchange-
Determinants of hypotension (human, infant)
** P50HL 19190-02 0009 Pulmonary SCOR-Pathophysiology,
management of IRDS - Developing non-invasive neonatal
pulmonary monitoring systems (rabbit, human)
ROlHL-19225-02 0004 Types and mechanims of
pulmonary hypertension - Structural changes in human
pulmonary circulation (human, animals)
POlHL-19737-02 0006 Cellular and molecular aspects of
respiratory physiology - Tissue oxygenation and
mitochondrial respiratory activity (sheep)
ROlHL-20354-02 Direct determination of oxygen tension in
the clinical environment (human, dogs)
** ROlHL-21176-02 Phospholipid exchange proteins in lung
tissue (lambs)
** ROlHL-22266-01 Production of proteases by lung cells in
culture (human, rodents, rabbits, sheep)
ROlHL-22327-01 Transport of arterial blood gases through
skin (swine)
ROlHL-22636-01 Newborn lung function during
mechanical ventilation (human)
•* ROlHL-22843-01 Pulmonary physiology in liquid ventilation
(lambs)
** NOlHR-62948-04 Evaluate antenatal steroid therapy in
neonatal respiratory distress syndrome
** NOlHR-62949-05 Evaluate antenatal steroid therapy in
neonatal respiratory distress syndrome
** N01HR-629S0-04 Evaluate antenatal steroid therapy in
neonatal respiratory distress syndrome
** NOlHR-62951-04 Evaluate antenatal steroid therapy in
neonatal respiratory distress syndrome
** NOlHR-62952-05 Evaluate antenatal steroid therapy in
neonatal respiratory distress syndrome
CONGENITAL ABNORMALITIES, SKIN (GENERAL)
P50HL-142 14-07 0020 Newborn lung center for hyaline
membrane disease - Epidermal growth factor effect-Lung
differentiation, maturation (human, rabbit)
CONGENITAL ABNORMALITIES, TERATOGENIC
AGENTS
SEE ALSO GENETICS, MUTAGENS
** ROIHL- 18050-04 Mechanisms of cardiovascular
teratogenesis (chick embryo) k embryo)
ROlHL-18848-03 Etiology and development of congenital
heart disease (dogs, cats)
ROlHL-19136-03 Mucopolysaccharide metabolism in
cardiac anomalies (rats)
CONGENITAL DISEASES
SEE CONGENITAL ABNORMALITIES
CONGENITAL HEART DISEASE
SEE CONGENITAL ABNORMALITIES, HEART DEFECTS
CONGENITAL IRON OVERLOAD (CEREBRO-
HEPATO-RENAL SYNDROME)
SEE METABOLIC DISORDERS INBORN, CEREBRO-HEPATO-
RENAL SYNDROME
CONGESTIVE HEART FAILURE
SEE HEART DISORDERS, HEART FAILURE, CONGESTIVE
CONJUNCTIVA
SEE EYE, CONJUNCTIVA
CONNECTIVE TISSUE (GENERAL)
SEE ALSO ALBUMINOIDS, COLUGEN
SEE ALSO ALBUMINOIDS. ELASTIN
SEE ALSO MUSCLES. SARCOLEMMA
SEE ALSO SKELETAL SYSTEM. BONE
SEE ALSO SKELETAL SYSTEM. CARTILAGE
** ROlHL-02942-22 Biochemistry of cardiovascular connective
tissue (human, cattle, primates)
POlHL-08682-15 0005 Regulation of the cardiovascular
system - Smooth muscle and mechanical properties of
blood vessels (dogs, human)
ROIHL- 12766-09 Structure-function relation of blood
vessels (rats, monkeys)
P50HL-14164-07 0036 A/S SCOR-Comparative and
experimental atherosclerosis - Connective tissue
metabolism-Interaction with arterial metabolism (monkeys)
** P50HL-15103-07 0014 A/S SCOR-Early natural history of
arteriosclerosis - Biochemistry of atherosclerotic lesions
(monkeys, human, cattle)
ROIHL 15478-05 Lipid flux and collagen synthesis in
atherosclerosis (rabbits)
** POlHL-15832-06 0001 Chemical-structural predispositions
to lung injury - Chemical composition of lung connective
tissue proteins (human, animals)
** POlHL-15832-06 0002 Chemical-structural predispositions
to lung injury - Connective tissue in lung in development
and repair of injury (human, rats, mice)
POlHL-15832-06 0005 Chemical-structural predispositions
to lung injury ■ Pulmonary structure and stress-strain
relationships (rats)
** POlHL-15832-06 0008 Chemical-structural predispositions
to lung injury - Interstitial fibrosis -Connective tissue
components in normal and diseased lungs
(contd)
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
CON
POIHL 1S832 06 0009 Chtmical structural predisposition!
to luni iniury Iminunoloiy Intymt d<gr<datioi\ products
ol trumtn luni dislin and microlibril
POIHl 15832 06 9001 CliDmical structural predispositions
to luni injury Tissue culture stud.es ol luni cell function
Core lacilitY
ROIHL 16010 16 Cellular basis ol cardiac contractility
(lro|s)
POIHL 1638' 04 0004 The blood vessel and
thrombogenesis Analysis ol vascular basement membiane
by eniymalic methods (human)
•• ROIHL W721 04 [Meet ol sex hormones on vascular
connective tissue (rats)
P50HL 18318 03 0015 Pathogenesis and complications ol
hypertension Cultured smooth muscle cells and
microvessel metabolism (mammals)
" POIHL 18645 03 0003 Biology ol the artery viall and
atherosclerosis Synthesis ol connective tissue proteins by
smooth muscle cells (human, monkeys)
ROIHL 19677 03 Venous structure and function (dogs)
POIHL 19717 02 0008 Response ol the lung to in|ury
Experimental models ol lung disease
•* POIHL 1971702 0009 Response ol the lung to iniury
Time dependent mechanical properties ol lung connective
tissues (hamsters)
** POIHL 19717 02 0012 Response ol the lung to in|ury
Connective tissue biochemistry and enzyme injury of the
lung (hamsters)
PO1HL1971702 0018 Response ol the lung to in|ur>
Lung mechanics and connective tissue composition in
human emphysema
** P01HL19717 02 0023 Response of the lung to injury
Postnatal lung development -Cells, connective tissue and
physiology (animals)
R01HL2162601 Proteoglycans of animal lung
parenchyma (cattle, pigs, rabbits)
ROlHL-21644 01 Fibronectin and related glycoproteins
(human, rodents)
ROlHL-2164901 Biochemistry of lung proteoglycans
(mammals)
ROlHL-21673-01 Pathophysiology ol venous changes in
hypertension (rats, rabbits, human, dogs)
ROlHL-2226401 Regulation ol contraction in vascular
smooth muscle (dogs)
ROlHL-23205-01 Contraction of pulmonary vascular
smooth muscle (cat)
CONNECTIVE TISSUE, ADIPOSE
POlHL-12373-10 0006 Cardiopulmonary physiology and
pathophysiology - Fatty acid metabolism-Regulation,
implications (human, mammals, birds)
P01HL12373-10 0012 Cardiopulmonary physiology and
pathophysiology - Biochemistry of the sympathetic nervous
system (rats, rabbits, pigeons)
ROlHL-1269009 Systemic and local vascular adjustment
in shock (monkeys, cats)
ROlHL-12974 10 Tracer kinetics, flovys and masses in
body organs (human, dogs)
R01HL14990-07 Lipid transport in avian species
(chickens)
ROlHL-15562-05 Regulation of skeletal muscle blood flow
(dogs)
ROlHL-1621905 Mechanisms of atherogenesis in chronic
uremia (human, rats)
ROlHL-16577-04 Lipoprotein lipase chemistry and function
(rats, cattle, human)
R01HL-1870503 Regulation of plasma triglyceride
metabolism (rats)
*♦ P50HL-1936202 0002 A/S SCOR-Atherosclerosis in
nonhuman primates ■ Infant caloric intake, adipose tissue
development and atherosclerosis (baboon)
ROlHL-20508-03 Diabetes, hyperglycemia and
cardiovascular disease (human)
ROlHL-21578-01 Effect of exercise upon the hypertensive
adolescent
ROIHL-22053-02 The disordered lipid metabolism of
diabetes mellitus (chickens, mammals, human)
ROlHL-22406-01 Isobaric vascular bubbles and
decompression sickness (goats, models)
POlHL-22633-01 0002 Cellular and molecular biology of
lipoprotein metabolism • Sterol metabolism in tissue
culture cells
POlHL-22633-01 9001 Cellular and molecular biology of
lipoprotein metabolism • Tissue culture core
ROlHL-23159-01 Regulation of lipogenesis by
polyunsaturated fats (rats, chicks)
CONNECTIVE TISSUE, ADIPOSE, FAT CELLS
P50HL-1423707 0002 Support for arteriosclerosis center
- Interactions of lipoprotein particles with vascular surface
(human, rat)
P50HL-19362-02 0002 A/S SCOR-Atherosclerosis in
nonhuman primates ■ Infant caloric intake, adipose tissue
development and atherosclerosis (baboon)
CONNECTIVE TISSUE, ELASTIC TISSUE
** P01HL11310-12 0101 Mechanisms of cardiovascular
disease - Molecular pathogenesis of vascular disease
POlHL-11310-12 0104 Mechanisms of cardiovascular
disease - Structure of connective tissue proteoglycans
(rabbits)
M POlHL-161 18-06 Study of emphysema
1*7
ROIHI 22446 01 Chemical and lunclional iludMi ol low
copper in lung (pig%)
HOI HI 22/3901 i volution and pto^le^Mon ol pediatric
atheioscleiosis
CONNECTIVE TISSUE, OROUNO SUBSTANCE
*• RUIHI 1862503 Organi/alion ol arterial ground lubilance
(cattle)
CONNECTIVE TISSUE CELLS
Sfl Also BLOOD AND Hf SYSTEM, MACROPHAGES
SEE ALSO BIOOD AND RF SYSTEM, MAST CELLS
SEE ALSO CONNECTIVE TISSUE, ADIPOSE, FAT CELLS
SEE ALSO MUSCLE CELIS
SEE ALSO PIGMENTATION, CHROMATOPHORES
ROIHL 18900 03 Intercellular lectors in luncti^n ol
cardiac cells
ROIHL 21994 01 Structure and development ol
regenerating capillaries (rabbits, chick embryo)
CONNECTIVE TISSUE CELLS, FIBROBLASTS
POIHL 06285 18 0152 Cardiovascular respiratory
physiology and biochemistry Diabetic microangiopathy by
organ and tissue culture (human)
ROIHL 10316 13 Structural studies on low density serum
lipoproteins (human)
ROIHL 12745 10 Enzymes and inhibitors of cholesterol
biosynthesis (rats, human, swine)
P50HL 14164 07 0037 A/S SCOR Comparative and
experimental atherosclerosis Genetic control of plasma
cholesterol Interaction of dietary fatty acid (monkey)
** P50HL 14212 07 0016 Correlated studies of pulmonary
fibrosis Role ol pulmonary alveolar macrophages in
fibrosis (human, rabbit)
P50HL 14230 07 0095 A/S SCOR Lipids, atheiosclerosis
and thrombosis Blood platelet adherence to endothelial
smooth muscle cells, fibroblast (human)
P50HL 1423007 9002 A/S SCOR-Lipids. atherosclerosis
and thrombosis - Core tissue culture laboratory
POlHL-15195-04 0002 Program project in biological
materials Structural and surface characterization
ROlHL-15646-03 Lipid studies in vascular smooth muscle
cells (human, monkeys)
ROlHL-15895-05 In vitro study of lipoproteins in vascular
disease (human, animals)
** ROIHL 16634-13 Regulation of metabolism in fibroblasts
and platelets (human, rabbits, sheep)
ROlHL-17404-05 Immunologic mechanisms in heart
disease (mice)
P50HL-17648-04 0026 Study of ischemic heart disease -
Control of muscle cell proliferation (organ culture)
ROlHL-17898-03 Cell membranes and plasma lipoproteins
(human, swine)
POIHL 18577-03 0001 Lipoproteins-Cell surface
interactions - Structural studies of serum lipoproteins in
man and dogs
POlHL-18577-03 0003 Lipoproteins-Cell surface
interactions - Mechanism of lipid exchange in lipoproteins
and cell membranes
POlHL-18645-03 0003 Biology of the artery wall and
atherosclerosis - Synthesis of connective tissue proteins by
smooth muscle cells (human, monkeys)
ROlHL-18687-03 Pathophysiology of genetic
hypertriglycerinemias (human)
R01HL-18692-03 Glycosaminoglycans and lipoproteins of
human plasma
ROlHL-18878-03 Familial hypercholesteremia-Studies of
fibroblasts (human)
ROlHL-194 19-03 Cellular interactions with foreign
materials (mammals)
R23HL-19594 01 Tropocollagen and tropoelastin uptake in
lung cells (human)
POlHL-197 17-02 0007 Response of the lung to injury -
Cellular level studies of prostaglandin-like molecules
(cattle)
POlHL-197 17-02 0024 Response of the lung to injury -
Formation of lung alveoli (rats)
ROlHL-19731-03 Collagen in interstitial fibrosis of lung
(human)
ROlHL-20095-03 Role of lymphokines and monocytes in
lung fibrosis (human, guinea pigs, rats)
ROlHL-20104-03 Pulmonary granulomatous inflammations
(mice)
ROlHL-20201-01 Hypertension and vascular steroid
receptors (rats)
ROlHL-20533-09 Pathogenesis of rheumatic fever (human,
rabbits)
M POlHL-20948-02 Molecular basis of cholesterol
metabolism
** POlHL-20948-02 0001 Molecular basis of cholesterol
metabolism - Biochemical and ultrastructural
characterization of LDL in human fibroblasts
POlHL-20948-02 0002 Molecular basis of cholesterol
metabolism - LDL pathway in cell lines with informative
properties other than fibroblasts
POlHL-20948-02 0003 Molecular basis of cholesterol
metabolism - LDL pathway in vivo (human, rats, guinea
pigs)
POlHL-20948-02 0004 Molecular basis of cholesterol
metabolism - Genetic analysi of the LDL pathway (human)
POlHL-20948-02 9001 Molecular basis of cholesterol
metabolism - Tissue culture i e laboratory
CON
R23H1 ?in4 02 Immune function and tibroianttit m
tillcoin ((uinen pig^l
ROIHI 21644 01 libroneclin and rdalMl ihrcoproltint
(human, rodnnti)
R23H1 21805 01 Tluue cell Inttfictioni with vitcular
prostheses (human. raM, mice)
ROIHI 225?/ 01 Proitacytlin thrornbomnej in the
cardiovascular iyilem (human, rabbits)
POIHl 22602 01 0001 Pathophy.iology ol the
endothelium Platelet endolhelial inleractioni in vitro
(human, cattle)
ROIHL 22623 01 Polyamines cellular medialort ol
atherogenesis (human)
POIHL 22633 01 0002 Cellular and molecular biology o(
lipoprotein metabolism Sterol metabolism in tittut
culture cells
CONNECTIVE TISSUE CEUS (NERVE)
SEt NERVOUS SYSTEM. NEUROGLIA
CONNECTIVE TISSUE DEVELOPMENT
*• P50HL 14218 07 0006 Pulmonary SCOR Newborn lung
center Biochemical characteristics ol the lung in RDS
(human, sheep)
ROIHL 18473 04 Genesis ol atherosclerotic lesions
(human, mules)
ROIHL 18714 04 Cardiovascular matrix Morphogenesis
and maturation (human, chick embryo, mammal)
** ROIHL 20635 03 Factors in lung development (rat and
chick embryo)
ROIHL 2076402 Elastin and calcification in pulmonary
and vascular disease (human, mammals)
** R23HL2122502 Connective tissue precursor molecules in
the lung (rabbits, hamsters)
ROIHL 21617 02 Biochemistry of lung proteoglycans
(rabbits, cattle)
ROlHL-21646 02 Biosynthesis of fractionated
proteoglycans ol lung (rabbits)
CONNECTIVE TISSUE DEVELOPMENT,
FIBROGENESIS
** ROIHL 12561 11 Cardiovascular studies on copper
deficiency (swine)
** ROIHL 14126 17 Effect of function on grafts and implants
of collagen (dogs, monkeys)
P50HL-14212-07 0004 Correlated studies of pulmonary
fibrosis - Collagen metabolism in lung tissue and lung
cells (human, animal)
P50HL-14212-07 0016 Correlated studies of pulmonary
fibrosis - Role of pulmonary alveolar macrophages in
fibrosis (human, rabbit)
** R23HL21134-02 Immune function and fibrogenesis in
silicosis (guinea pigs)
** ROlHL-22208-02 Elastin structure, fibrogenesis and
disease (chickens, rabbits)
ROlHL-23542-01 Pulmonary vascular smooth muscle cell
dynamics (rat. rabbit)
CONNECTIVE TISSUE DISORDERS (GENERAL)
SEE ALSO LIPOIDAL DISORDERS
SEE ALSO METABOLIC DISORDERS INBORN. EHLERS-DANLOS
SYNDROME
SEE ALSO METABOLIC DISORDERS INBORN. MARFAN
SYNDROME
ROlHL-12561-11 Cardiovascular studies on copper
deficiency (swine)
ROlHL-12869-09 Arterial metabolism, diabetes and
atherogenesis (rats, rabbits)
POlHL-16118-06 0006 Study of emphysema - Metabolism
of elastin (hamsters)
ROlHL-19685-03 Pathogenesis of inflammation of the lung
(guinea pigs)
** R01HL-20447-03 Connective tissue and diabetic vascular
disease (human)
CONNECTIVE TISSUE DISORDERS, COLLAGEN
DISEASES
SEE ALSO CEREBROVASCULAR DISORDERS. TEMPORAL
ARTERITIS
SEE ALSO CONNECTIVE TISSUE DISORDERS. LUPUS
ERYTHEMATOSUS SYSTEMIC
SEE ALSO CONNECTIVE TISSUE DISORDERS. RHEUMATIC
DISORDERS
SEE ALSO CONNECTIVE TISSUE DISORDERS, SCLERODERMA
SEE ALSO CONNECTIVE TISSUE DISORDERS. SJOGREN'S
SYNDROME
SEE ALSO GASTROINTESTINAL DISORDERS. ENTERmS.
ULCERATIVE COLITIS
** P50HL-15061-07 0004 Response of lung to injury -
Biochemical abnormalities in connective tissues (rats)
** ROlHL-17551-04 Biosynthesis and metabolism of
procollagen (human, monkeys, mice)
** R01HL-17909-04 Drug treatment of vascular scleroprotcin
defects (human, turkeys)
ROIHL-19633-02 Pathogenesis and pharmacology of lung
fibrosis (rats, rabbits)
" ROlHL-19668-03 Biochemistry of lung connective tissue
(rats)
R01HL-19720-03 Evaluation of anti-fibrotic agents in
pulmonary fibrosis (rats)
** ROlHL-19731-03 Collagen in interstitial fibrosis of lung
(human)
ROlHL-20095-03 Role of lymphokines and monocytes in
lung fibrosis (human, guinea pigs, rats)
(contd)
'Excludes routine methodology OR covers only general projects which preclude
••Oriented significantly to above subject.
indexing at the specific level.
M Grant has subprojects describing specific
See Appendix for investigator's name and gr
research aspects,
ant number.
CON
ROlHL-20675-02 Alveolar macrophage function in man
R23HL-21663-01 Regulation of collagen biosynthesis
(chick, embiyo)
** ROlHL-22939-01 Human kinin and fibrinolytic systems
and renal disease (human)
CONNECTIVE TISSUE DISORDERS, LUPUS
ERYTHEMATOSUS SYSTEMIC
POlHL-06314-17 0062 Immunologic mechanisms in
cardiovascular disease - Immunologic renal vascular
disease (human, animals)
ROlHL-1003613 Biology of red cell antigen-antibody
reaction (human)
" R01HH0980-11 Ultrastructural renal pathology (human,
rats)
POlHL-12738-10 0001 Physiologic pharmacology and its
clinical applications - Clinical pharmacology of cardioactive
drugs (human)
ROlHL-1660305 Human and experimental renal diseases
(animals)
CONNECTIVE TISSUE DISORDERS, RHEUMATIC
DISORDERS
SEE ALSO BACTERIAL DISEASES, STREPTOCOCCAL
INFECTIONS, RHEUMATIC FEVER
SEE ALSO SKELETAL DISORDERS, ARTHRITIS, RHEUMATOID
M R01HL01803-23 Arteriosclerosis, glomerulonephritis,
rheumatic fever
CONNECTIVE TISSUE DISORDERS, RHEUMATIC
DISORDERS, ANTIRHEUMATIC AGENTS
SEE ALSO CALCIFICATION INHIBITORS (CALCIUM NEGATIVE
BALANCE DRUGS)
SEE ALSO DISEASES, PATHOLOGIC PROCESSES,
INFLAMMATION, ANTIINFLAMMATORY AGENTS
ROlHL-18679-04 Synthetic protease inhibitors
CONNECTIVE TISSUE DISORDERS,
SCLERODERMA
ROlHL-10009-13 Regional lung function m man
R01HL-14U8-07 0008 The regional circulations - Renal
circulation in hypertensive patients (also dogs)
R01HL'166D3-05 Human and experimental renal diseases
(animals)
POlHL-17813-04 0001 Lung disease and the oxygenation
of blood and tissue - Diffuse interstitial lung disease-
Pathophysiology (human, dogs)
POlHL-17813-04 0006 Lung disease and the oxygenation
of blood and tissue - Assessment of respiratory muscle
contractile force (human, dogs)
R01HL-19731-O3 Collagen in interstitial fibrosis of lung
(human)
ROlHL-22547-01 Behavioral treatment of Raynaud's
disease (human)
CONNECTIVE TISSUE DISORDERS, SJOGREN'S
SYNDROME
P50HL-14153-07 0016 Johns Hopkins Lung Center-
Chronic diseases of airways - Airways defense mechanisms
(dogs)
CONNECTIVE TISSUE DISORDERS
CHEMOTHERAPY
SEE ALSO CONNECTIVE TISSUE DISORDERS, RHEUMATIC
DISORDERS, ANTIRHEUMATIC AGENTS
SEE ALSO CONNECTIVE TISSUE PHARMACOLOGY
** ROIHL 17909-04 Drug treatment of vascular scleroprotein
defects (human, turkeys)
** ROlHL-19720-03 Evaluation of anti-fibrotic agents in
pulmonary fibrosis (rats)
CONNECTIVE TISSUE HYPERPLASIA
SEE ALSO HEART DISORDERS, CORONARY FIBROSIS
SEE ALSO METABOLIC DISORDERS INBORN, CYSTIC FIBROSIS
SEE ALSO RESPIRATORY DISORDERS, PULMONARY FIBROSIS
AND GRANULOMAS
** R01HL-17369-04 Arterial bypass surgery-Structure and
metabolism (monkeys)
CONNECTIVE TISSUE PHARMACOLOGY
SEE ALSO CONNECTIVE TISSUE DISORDERS CHEMOTHERAPY
R01HL-17909-D4 Drug treatment of vascular scleroprotein
defects (human, turkeys)
CONSCIOUSNESS
SEE PSYCHOLOGY, COGNITION, CONSCIOUSNESS
CONSTITUTIONAL HIRSUTISM
SEE DISEASES, SIGNS-SYMPTOMS, HIRSUTISM
CONSULTATION AND REFERRAL
SEE HEALTH CARE SERVICES, REFERRAL AND CONSULTATION
CONSUMER PRODUCTS
SEE ALSO BIOLOGICAL PREPARATIONS AND STANDARDIZATION
SEE ALSO BIOMATERIALS
SEE ALSO BIOMEDICAL ENGINEERING
SEE ALSO BIOMEDICAL RESOURCES (GENERAL)
SEE ALSO DRUGS
SEE ALSO IMMUNOLOGICAL PREPARATIONS
(GENERAUdNCLUDING CERTIFICATION AND
STANDARDIZATION)
SEE ALSO PHYSICAL PROPERTIES, SURFACTANTS,
DETERGENTS
168
R23HL-22895-01 Smoke inhalation-Biochemical and
cellular responses (rabbits, bacteria)
CONSUMER PRODUCTS, TOBACCO AND
TOBACCO PRODUCTS
SEE ALSO PSYCHOLOGY, HABITS, SMOKING
SEE ALSO PYRIDINES. NICOTINE
R01HL-01803-23 0011 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Immunopathologic consequences of
cigarette smoking (human, rabbits, plants)
" ROlHL-01803-23 0021 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Induction of IgE antibodies to antigen
from tobacco and cigarette smoke (rabbits)
** ROlHL-01803-23 0022 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Cardiac and pulmonary anaphylaxis
induced by tobacco glycoprotein (rabbits)
** P50HL-142 12-07 0012 Correlated studies of pulmonary
fibrosis - Inorganic particulates in tobacco, smoke and
lungs of cigarette smokers (human)
ROIHL 16029-05 Bio-organic chemistry of ozone, nitrogen
dioxide and tobacco smoke
ROlHL-16674-05 Airborne metals and lung permeability
(bullfrogs, rats)
P50HL-18828-03 0006 Specialized center of research in
thrombosis - Etiology and pathogenesis of atherosclerosis
(rabbit, monkey, rat, human)
CONTACT INHIBITION
SEE CELL GROWTH REGULATION, CONTACT INHIBITION
CONTAMINATION (GENERAL)
SEE ENVIRONMENTAL HEALTH, CONTAMINATION (GENERAL)
CONTINUING EDUCATION, HEALTH
OCCUPATIONS
SEE EDUCATION, HEALTH OCCUPATIONS. CONTINUING
EDUCATION
CONTINUITY OF PATIENT CARE
SEE HEALTH CARE SERVICES. PATIENT CARE MANAGEMENT,
COMPREHENSIVE CARE
CONTRACEPTION
SEE FAMILY PLANNING
SEE FERTILITY, ANTIFERTILITY DRUGS
CONTRACTILE PROTEINS
SEE MUSCLE PROTEINS (AND CONTRACTILE PROTEINS)
CONTRACTION
SEE MUSCLE FUNCTION, MUSCLE CONTRACTION
SEE PROTEINS CONTRACTION
CONTRAST MEDIA
SEE RADIOGRAPHY. CONTRAST MEDIA*
CONTROL
SEE COMMUNICABLE DISEASE CONTROL
SEE FERTILITY, ANTIFERTILITY DRUGS
SEE HEALTH SOCIAL CONTROL
CONTROL OF VISCERAL RESPONSES BY SELF
REGULATION
SEE PSYCHOLOGY, CONDITIONING. AUTOGENIC AND INTERNAL
CONTROL
CONVERTING VIRUSES
SEE VIRUS CHARACTERISTICS, TRANSFORMING VIRUSES
CONVULSIONS
SEE NEUROMOTOR DISORDERS. CONVULSIONS
COOLEY'S ANEMIA
SEE HEMOPROTEINS, HEMOGLOBINOPATHIES, THAUSSEMIA
COOPERATIVE MODEL
SEE BIOLOGICAL TRANSPORT. MEMBRANE MODELS
COOPERATIVE STUDY
N01HB-53016-05 Cooperative study of factor VIII inhibitors
in patients with hemophilia
** N01HB-530 18-04 Cooperative studies of factor VIM
inhibitors in patients with hemophilia
NOlHB-530 19-06 Cooperative study of factor VIII inhibitors
in patients with hemophilia
N01HB-53020-04 Cooperative study of factor VIII inhibitors
in patients with hemophilia
N01HB-53021-05 Cooperative study of factor VIII inhibitors
in patients with hemophilia
N01HB-53023-04 Cooperative study of factor VIII inhibitors
in patients with hemophilia
N01HB-53024-04 Cooperative studies of factor VIII
inhibitors in patients with hemophilia
N01HB-53025-05 Cooperative studies of factor VIII
inhibitors in patients with hemophilia
NOlHB-53035-04 Factor VIII inhibitors in patients with
hemophilia
NOlHB-62970-02
granulocytes
NOlHB-62973-05
granulocytes
** N01HB-72982-03
cell disease
** ROlHL-08888-12 Cooperative study of drugs and coronary
heart disease (men)
** R01HL08892-10 Cooperative study of drugs and coronary
heart disease
Collection, function and transfusion of
Collection, function and transfusion of
Statistical coordinating center for sickle
COO
ROlHL-09474-11 Natural history-congenital heart defects-
Joint study (human)
ROlHL-09476-10 Natural history, congenital heart defects-
Joint study
ROlHL-10445-09 Cooperative study of drugs and coronary
heart disease (men)
ROlHL-10705-09 Cooperative study of drugs and coronary
heart disease (men)
ROlHL-10711-12 Cooperative study of treatment of
hypertension (human)
ROlHL-10718-10 Natural history of congenital heart
defects-Joint study (human)
ROlHL-11372-08 Cooperative study of drugs and coronary
heart disease (men)
ROlHL-12542-07 Natural history, congenital heart defects-
Joint study (human)
ROlHL-15374-03 Cooperative study of drugs and coronary
heart disease (human)
ROIHL- 16908-04 Myocardial function, risk factors and
future CHD (men)
ROIHL- 16909-04 Myocardial function, risk factors and
future CHD (men)
P50HL-17655-04 0009 Study of ischemic heart disease -
Random trial of medical and surgical therapy in unstable
angina (human)
P50HL-17665-04 0013 Study of ischemic heart disease -
National cooperative study in unstable angina pectoris
(human)
ROlHL-18943-03 Contractile activity of single cardiac cells
ROlHL-19138-03 Contractile activation of skinned cardiac
cells (mammals)
ROlHL-20374-03 Myocardial function-Risk factors and
future CHD (human)
ROlHL-21039-02 Vascular lesions of diabetes in Oklahoma
Indians
NOlHR-62942-04 Nocturnal oxygen therapy in chronic
hypoxic lung disease (humam)
N01HR-62943-05 Nocturnal oxygen therapy in chronic
hypoxic lung disease (human)
N01HR-62944-04 Nocturnal oxygen therapy in chronic
hypoxic lung disease (human)
NOlHR-62945-04 Nocturnal oxygen therapy in chronic
hypoxic lung disease (human)
NOlHR-62946-04 Nocturnal oxygen therapy in chronic
hypoxic lung disease (human)
NOlHR-62947-04 Nocturnal oxygen therapy in chronic
hypoxic lung disease (human)
NOlHR-62948-04 Evaluate antenatal steroid therapy In
neonatal respiratory distress syndrome
NOlHR-62949-05 Evaluate antenatal steroid therapy in
neonatal respiratory distress syndrome
NOlHR-62950-04 Evaluate antenatal steroid therapy in
neonatal respiratory distress syndrome
NOlHR-62951-04 Evaluate antenatal steroid therapy In
neonatal respiratory distress syndrome
NOlHR-62952-05 Evaluate antenatal steroid therapy In
neonatal respiratory distress syndrome
NOlHR-72902-04 Study of intermittent positive pressure
breathing
NOlHR-72903-05
breathing
NOlHR-72904-03
breathing
NOlHR-72905-03
breathing
NOlHR-72906-03
breathing
N01HV-12017-15
for plastic heart assist devices
Study of intermittent positive pressure
Study of intermittent positive pressure
Study of intermittent positive pressure
Study of Intermittent positive pressure
Fabrication of grafted hydrogel coatings
Development of intimal linings (human.
Lipid research clinic
Establishment of a lipid research clinic
Lipid research clinic
Establishment of a lipid research clinic
Therapy for hypertension in the general
'Excludes routine methodology OR covers only general protects which preclude indexing at the specific level.
"Oriented significantly to atwve subject.
NOlHV-12054-14
cattle)
NOlHV-12156-10
NOlHV-12158-10
N01HV-12159-09
NOlHV-12160-15
NOlHV-12434-11
population
NOlHV-12436-15 Hypertension therapy in the general
population (human)
N01HV-12440-14 Therapy for hypertension in the general
population (human)
NOlHV-12442-14 Therapy for hypertension in the general
population (human)
NO lHV-229 13-09 Lipid research clinic
NO lHV-229 14-08 Establishment of a lipid research clinic
NOlHV-22945-11 Cooperative hypertension detection and
follow-up study (human)
N01HV-22971-07 Prevention of coronary heart disease
(human)
NOlHV-22977-08 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22979-07 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22980-06 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22981-10 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22982-07 Intervention trial for prevention of
coronary heart disease (human)
N01HV-22983-G7 Intervention trial for the prevention of
coronary heart disease (human)
Icontd)
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
Collabofative studies on coronary artery
COO
NUIHV .1.'9I3 11 Study elettrodaless iluw diii:l\at||g loi
moditying polymer surface
" NOIHV 3.'931 09 Istdblrstimenl ol a lipid lesearcli clinic
center
•• NOIHV 32933 0/ Hypertension deleition and lollow up
program central laboratory (human)
" NOIHV 32974 U9 Collaborative studies on coronary artery
surgery (human)
•* NOIHV 329?b 08 Collaborative Studies on coronary artery
surgery (human)
*■ NOIHV 32976 09 Collaborative studies on coronary artery
surgery (human)
" NOIHV 32978 08 Collaborative studies on coronary artery
surgery
NOIHV 32979 09
surgery
•* NOIHV 32980 07 Collaborative studies on coronary artery
surgery (human)
** NOIHV 32981 to Collaborative studies on coronary artery
surgery (human)
** NOIHV 32983 II Collaborative studies on coronary artery
surgery (human)
•* NOIHV 32984 10 Collaborative studies on coronary artery
surgery (human)
NOIHV 32985 II Collaborative studies on coronary artery
surgery (human)
" NOIHV 33105 09 Intervention trial tor prevention of
coronary heart disease (human)
** NOIHV 33106 06 Intervention trial for the prevention of
coronary heart disease (human)
" NOIHV 42929 08 Risk factor intervention trial for the
prevention ol CHD (human)
** NOIHV 4293009 Risk factor intervention trial for the
prevention of CHO (human)
** NOIHV 42933 09 Multiple risk factors in coronary heart
disease (human)
** N01HV-5290106 Aspirinmyocardial infarction study
** NOIHV 5294104 Center for aspirin-myocardial infarction
study (human)
** N01HV-5301509 Establishment of a lipid research clinic
(human)
** NOlHV-72940-02 Therapy to protect ischemic myocardium
(human)
** NOlHV-72941-02 Therapy to protect ischemic myocardium-
Clinical tests
** NOlHV-72942-02 Therapy to protect ischemic myocardium-
Clinical tests
** NOlHV-72948-03 Coordinating center for propranolol heart
trial (human)
** NOlHV-72949-03 ECG center for proprancolo heart trial
" N01HV-7295002 Central laboratory for propranolol heart
trial
** NOlHV-7295103 Clinical center for propranolol heart trial
(human)
♦* NOlHV-72952-02 Clinical center for propranolol heart trial
(huamn)
** NOlHV-72954-06 Clinical center for propranolol heart trial
(human)
** NOlHV-72955-02 Clinical center for propranolol heart trial
(human)
** NOlHV-7295602 Clinical center for propranolol heart trial
(human)
** NOlHV-72957-02 Clinical center for propranolol heart trial
(human)
** NOlHV-7295802 Clinical center for propranolol heart trail
(human)
" NOlHV-72959-04
(human)
** NOlHV-72960-02
(human)
** NOlHV-72961-03
** NOlHV-72963-02
(human)
" NOlHV-7296402
(human)
** NOlHV-72965-02 Clinical center for propranolol heart trial
** NOlHV-72966-03 Clinical center for propranolol heart trial
** NOlHV-72967-02 Clinical center for propranolol heart trial
(human)
** ND1HV-7296803 Clinical center for propranolol heart trial
** N01HV-72969-02 Clinical center for propranolol heart trial
(human)
** N01HV-72970-04 Clinical center for propranolol heart trial
(human)
*" NOlHV-82900-03 Clinical center for propranolol heart trial
(human)
" NOlHV-82901-02
(human)
** NOlHV-82902-02
(human)
" NblHV-82903-02
(human)
" N01HV-82904-02
(human)
•* NOlHV-8290502
(human)
•* N01HV-82905-02
(human)
** NOlHV-8290702 Clinical center for propranolol heart trial
(human)
*♦ NOlHV-82908-02 Clinical center for propranolol heart trial
(human)
169
Clinical I enter lui propinnolnl heiil liiil
Clinical center lor propranolol hrart trial
Clinical center for propranolol heart trial
Clinical center propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol trial
Clinical center for propranolol heart trial
•• NOIHV K2909 0,'
(huiimnl
•• NOIMV 82910 00
(human)
" NOIHV 82915 01 therapy lor hypertension in the gentril
population (human)
COORDINATION COMPOUNDS, METAL
SI I 1141 lAI COMI'IIXIS
COPING BEHAVIOR
S(f PSYCMOLOGICAl AOAPIAIION, COPING BEHAVIOR
COPOIYMERS
?ff MOLfCUUR CONDENSATIONS, COPOLYMERS
COPPER
SEE MtTAlS. HEAVY METAIS. COPPER
COPROSTEROL
SEE CHOUSTANE SERIES 5-BETA, COPROSTEROL
COR PULMONALE
SEE RESPIRATORY CIRCULATORY DISORDERS, PULMONARY
HEART DISEASE
CORE, VIRAL
SEE VIRUS COMPONENTS, CORE
CORI'S DISEASE
SEE METABOLIC DISORDERS INBORN. GLYCOGENOSIS. TYPE
III
CORN OIL
SEE LIPIDS. OILS, VEGETABLE OILS
CORNEA
SEE EYE, CORNEA
CORONARY ARTERIES
SEE HEART VESSELS, CORONARY ARTERIES
CORONARY ARTERY SURGERY
SEE HEART REVASCULARIZATION
CORONARY BYPASS
SEE HEART REVASCUURIZATION, CORONARY BYPASS
CORONARY CARE UNITS
SEE HOSPITALS, INTENSIVE CARE UNITS, CORONARY
CORONARY CIRCULATION
SEE HEART CIRCUUTION
CORONARY DILATORS
SEE CARDIOVASCULAR AGENTS. VASODIUTORS. CORONARY
CORONARY DISORDERS
SEE HEART DISORDERS, CORONARY
CORONARY FIBROSIS
SEE HEART DISORDERS, CORONARY FIBROSIS
CORONARY OCCLUSIONS AND THROMBOSIS
SEE HEART DISORDERS, CORONARY OCCLUSIONS AND
THROMBOSIS
CORONARY REVASCULARIZATION
SEE HEART REVASCULARIZATION
CORONARY SINUS
SEE HEART VESSELS, CORONARY VEINS, CORONARY SINUS
CORONARY VEINS
SEE HEART VESSELS, CORONARY VEINS
CORONARY VESSELS, HEART
SEE HEART VESSELS
CORPORA QUADRIGEMINA
SEE BRAIN, MESENCEPHALON, COLLICULUS INFERIOR
CORTICOSPINAL TRACTS
SEE NERVOUS SYSTEM CENTRAL, PYRAMIDAL TRACTS
CORTICOSTEROID BINDING GLOBULINS
SEE GLOBULINS, CORTICOSTEROID BINDING GLOBULIN
CORTICOSTEROIDS
SEE ADRENAL CORTEX HORMONES
CORTICOSTERONE
SEE ADRENAL CORTEX HORMONES, CORTICOSTERONE
CORTICOTROPIN
SEE PITUITARYDIENCEPHALON HORMONES. ACTH
CORTISONE
SEE ADRENAL CORTEX HORMONES. CORTISONE
CORYNINE
SEE ALKALOIDS, RAUWOLFIA TYPE, YOHIMBINE
CORYZA AGENT OF CHIMPS
SEE VIRUSES, MYXOVIRUSES, RESPIRATORY SYNCYTIAL
VIRUSES
COTHROMBOPLASTIN
SEE BLOOD COAGULATION, FACTOR VII
COTTON DUST PNEUMONITIS
SEE RESPIRATORY DISORDERS, BYSSINOSIS
COUGHING
Ml HIM-IHAIORY ■■.YMfM REFLfXtS
COUMADIN
•,( I HI N/(l Al PHA I'YHONES, WARFARIN
COUMARINS
S(t H(N/0 AlI'llA I'YKONI',
COUNSELING (PSYCHOLOGY)
S(f MINIAI HfAIIII '.fRVICFS, COUNSELING
COUNSELING, GENETIC
SEE GfNFIIC DISORDERS, GENETIC COUNSIUNG
COUNTERPULSATION ARTERIAL
SEE CARDIOVASCUIAR SUHGf RY CIRCULATCRY ASSIST,
COUNIfRPUISAIION
COVALENT BONDS
SEE CHEMICAl BONDS. COVALENI
COXSACKIE VIRUSES
SEE VIRUSES. PICORNAVIRUSES, COXSACKIE VIRUSES
CREATINE
SEE AMINO ACIDS, CREATINE
CREATINE KINASE
SEE PHOSPHOTRANSFERASES, ATP CREATINE
PHOSPHOTRANSFERASE
CREATINE PHOSPHATE
SEE AMINO ACIDS, CREATINE PHOSPHATE
CREATININE
SEE AMINO ACIDS, CREATININE
CRECITUS
SEE MAMMALS, RODENTS, MYOMORPHA, HAMSTERS-
CRIB DEATH
SEE CHILDREN. INFANT AND CHILD MORTAUTY. SUDDEN
INFANT DEATH SYNDROME
CROSS CIRCULATION, SURGICAL
SEE CARDIOVASCULAR SURGERY, EXTRACORPOREAL
CIRCULATION, CROSS CIRCULATION
CROSS IMMUNITY
SEE IMMUNITY, CROSS IMMUNITY
CROSSLINKS (CHEMICAL BONDS)
SEE CHEMICAL BONDS, CROSSLINKS
CROTON OIL
SEE LIPIDS, OILS, CROTON OIL
CRUSH SYNDROME
SEE KIDNEY DISORDERS, NEPHROSIS LOWER NEPHRON
CRUSTACEANS
SEE ARTHROPODS. CRUSTACEANS*
CRYOFIBRINOGEN
SEE BLOOD COAGULATION, CRYOFIBRINOGEN
CRYOFRACTURE ETCHING METHOD
SEE TEMPERATURE, FREEZEETCHING*
CRYOGLOBULINS
SEE GLOBULINS, CRYOGLOBULINS
CRYOPRESERVATION
SEE TEMPERATURE, CRYOSCIENCES. LOW TEMPERATURE
PRESERVATION AND STORAGE
CRYOPROTECTIVE AGENTS
SEE TEMPERATURE, CRYOPROTECTIVE AGENTS
CRYOSCIENCES
SEE TEMPERATURE, CRYOSCIENCES
CRYOSURGERY
SEE TEMPERATURE (BODY), HYPOTHERMIA INDUCED,
CRYOSURGERY
CRYOTHERAPY
SEE TEMPERATURE (BODY), HYPOTHERMIA INDUCED.
CRYOTHERAPY
CRYSTALLIZATION
SEE PHYSICAL PROPERTIES. CRYSTALS. CRYSTALLIZATION
CRYSTALLOGRAPHY
SEE CHEMISTRY, ANALYTICAL METHODS, CRYSTALLOGRAPHY*
CRYSTALS
SEE PHYSICAL PROPERTIES CRYSTAl": CRYSTALLIZATION
CUUCIDS
SEE ARTHROPODS, INSECTS, DIPTERA, CUUCIDS,
MOSQUITOES*
CULTURE
SEE SOCIOLOGY AND ANTHROPOLOGY OTHER, CULTURE
CULTURE MEDIA
SEE GROWTH MEDIA
CULTURES
SEE GROWTH MICROORGANISMS, MICROBIAL CULTURE
(contd)
'Excludes routine methodology OR covers only general projects whicli preclude indexing at the specific level.
**Oriented significantly to above subiect.
M Gram has sut)pro)ects describing specific research aspects.
See Appendix for investigator's name and grant number.
CUP
170
CYC
SEE TISSUE (CELL) CULTURE*
CUPREINS, CYTOCUPREINS
SEE METALLOPROTEINS. CYTOCUPREINS
CURARIFORM DRUGS
SEE MUSCLE RELAXANTS
CURRICULUM
SEE EDUCATION, CURRICULUM
CUSHING'S SYNDROME
SEE ADRENAL GLANDS DISORDERS, HYPERADRENALISM,
CUSHING'S SYNDROME
CUTANEOUS SENSORY NERVES
SEE NERVOUS SYSTEM. AFFERENT NERVES. CUTANEOUS
SENSORY NERVES
CYANATES
SEE ALSO THIOCYANATES
** NOlHB-22919-08 Hemoglobin carbamylation in the
treatment of sickle cell anemia (human, dogs)
NOlHB-22922-08 Develop effective therapy for sickle cell
disease (human, dogs)
** NOlHB-62962-02 Red cell distributions in cyanate-treated
blood (human, sheep)
ROlHL-02799'22 Abnormal hemoglobins (human)
R01HL12174-11 Ventilation/perfusion distribution in the
lung (human, mammals)
** P60HL 1516905 0018 Support for center for sickle cell
disease - Studies on sickle cell disease (human, rats,
dogs)
** P60HL1599905 0008 Miami comprehensive sickle cell
center - Cyanate effect on host defense-Cellular and
humoral (human, guinea pig. rabbits)
R01HLie375'04 Investigation of hemoglobin S properties
(human)
P01HL'ie833'04 0001 Hemoglobin and red cell system in
hemoglobinopathies - Motility, association and ligand
binding in hemoglobin-Hydrogen exchange
POIHL'16833'04 0011 Hemoglobin and red cell system in
hemoglobinopathies - Relationship between hemoglobin and
RBC membrane in sickling cells (human, rats)
P01HL'ie83304 0014 Hemoglobin and red cell system in
hemoglobinopathies ■ Erythrocyte membrane damage in Hb
SS disease (human)
** ROIHL 18819-07 Chemical studies on sickle cell
hemoglobin (human)
ROlHL-22780-01 Factors modifying the reaction properties
of HgS (human)
CYANATES, ISOCYANATES
** P50HL1509207 0005 Immune and fibrotic response to
occupational environments - Respiratory and immunologic
evaluation of toluene diisocyanate exposure (human)
** P50HL-15C92-07 0010 Immune and fibrotic response to
occupational environments - Characterization of toluene
diisocyanate in industrial environments
P50HL-15092-07 0014 Immune and fibrotic response to
occupational environments - Clinical immunology core
resource
** P60HL-15160-07 0008 Center for sickle cell disease -
Isocyanate derivatives and hemoglobin S association
(human, rat)
CYANIDES
SEE ALSO IRON CYANIDES
ROlHL-17403-03 Metabolic control of cardiac output
(dogs)
ROIHL'18630'03 Pulmonary hemodynamics in atelectasis
and hypoxia (dogs)
POlHL-19737-02 0009 Cellular and molecular aspects of
respiratory physiology - Regulation of tissue oxygen tension
and body carbon monoxide stores (human, dogs)
CYANIDES, ALKYL NITRILES
P01HL-0637a-17 0015 Cardiopulmonary and renal
pathology research center - Pathogenesis of chemically
induced tissue injury (rats)
CYANIDES, AMINOALKYL NITRILES, BAPN
POIHL 16118-06 0006 Study of emphysema - Metabolism
of elastin (hamsters)
RClHL-16437-05 Drug treatment of atherosclerosis
(rabbits, monkeys)
RClHL-19428-03 Role of angiotensin sensitivity in renin
release (human)
R0IHL19633-02 Pathogenesis and pharmacology of lung
fibrosis (rats, rabbits)
CYANINE
SEE ALSO BENZOPYRROLES, INDOCYANINE GREEN
SEE ALSO MEROCYANINES
R01HL-177O2 04 Electro-optical dyes as probes of heart
excitability
R01HL-2025402 Probes of heart and nerve membranes-
Fluorescent dyes
CYANINS
SEE MCTALLOPROTEINS. HEMOCYANIN
CYANOCOBALAMIN
SEE VITAMIN B12
CYANOSIS
SEE RESPIRATORY GAS LEVELS. CYANOSIS
CYBERNETICS
SEE BIOMEDICAL SYSTEMS AUTOMATED. MONITORING
DEVICES
SEE BIOMEDICAL SYSTEMS AUTOMATED. PATIENT
MONITORING (MONITORING DEVICES)
CYBERNETICS (BIOLOGICAL)
SEE INFORMATION PROCESSING AND CONTROL (BIOLOGICAL)
CYBERNETICS (COMPUTER ARTIFICIAL
INTELLIGENCE (GENERAL))
SEE COMPUTER. ARTIFICIAL INTELLIGENCE, PATTERN
RECOGNITION AND CONTROL SYSTEMS
CYBERNETICS (COMPUTER) GENERAL
SEE COMPUTER, ARTIFICIAL INTELLIGENCE, PAHERN
RECOGNITION AND CONTROL SYSTEMS
CYBERNETICS (NEURAL)
SEE INFORMATION PROCESSING AND CONTROL (NEURAL)
CYCLASE (ADENYL CYCLASE)
SEE NUCLEOTIDYL-CYCLASES, ADENYLATE CYCLASE
CYCLASE, GUANYL CYCLASE
SEE NUCLEOTIDYL CYCLASES, GUANYUTE CYCLASE
CYCLIC AMINO ACIDS
R01HL-12526-09 Raman spectra of heme proteins and
related molecules
POlHL-18974-03 0012 Experimental neurogenic
hypertension program - Immunohistochemistryofcentral
monoam ineneurons(rats)
CYCLIC AMINO ACIDS, DOPA
ROlHL-17754-03 Pathogenesis and prevention of
hypertension sequelae (rats)
ROlHL-20 194-01 Brain catecholamines in control of blood
pressure (rats)
R01HL-2110S-02 Organ specific drugs-Cardiovascular and
renal effects (dogs)
CYCLIC AMINO ACIDS, DOPA, ALPHA-METHYL
DOPA
POlHL-06835-17 0037 Cardiovascular disease - Cardiac
hypertrophy in spontaneously hypertensive rat
P01HL-0e83S-17 0057 Cardiovascular disease - Studies
on cardiac hypertrophy
POlHL-06835-17 0060 Cardiovascular disease -
Ventricular performance experimental models of arterial
hypertension (rats, dogs)
R01HL-10942-09 Study of genetic hypertension in rats
ROlHL-17754-03 Pathogenesis and prevention of
hypertension sequelae (rats)
POlHL-17871-04 0009 Kidney, sodium, cardiac output,
arterioles and hypertension - Kidney, sodium, cardiac
output, arterioles and hypertension
ROlHL-20087-02 Developmental processes in pulmonary
hypertension (rats)
** ROlHL-201 94-01 Brain catecholamines in control of blood
pressure (rats)
POlHL-20552-02 0002 The development and regression of
cardiac hypertrophy - Effect of treatment on the
hypertrophied left ventricle (rats)
POlHL-20552-02 0003 The development and regression of
cardiac hypertrophy - Muscle mechanics of the
hypertrophied lett ventricle (rats)
ROlHL-22032-01 Cardiovascular events in hypertensives
(human)
CYCLIC AMINO ACIDS, HISTIDINE
POlHL-15596-05 0007 Coagulation, fibrinolysis,
hemostasis and hepatitis - Structural studies and
fractionation of urokinase (human)
ROlHL-18905-04 Acquisition of native conformation of
proteins (human, cattle)
ROlHL-21461-01 Heme group protein interactions In
hemoproteins
CYCLIC AMINO ACIDS, PHENYLALANINE
SEE ALSO CYCLIC AMINO ACIDS, DOPA
SEE ALSO CYCLIC AMINO ACIDS, TYROSINE
POlHL-151 95-04 0001 Program project in biological
materials - Design and synthesis
ROlHL-18258-04 Regulation of protein degradation in
heart (rats)
R01HL-20070-02 Alpha-1-antitrypsin deficiency (human,
hamsters)
CYCLIC AMINO ACIDS, PHENYLALANINE, P-
CHLOROPHENYLALANINE
ROlHL-147 13-06 Hypothermia and the heart (bats, guinea
pigs)
CYCLIC AMINO ACIDS, PROLINE
POlHL-161 18-06 0004 Study of emphysema - Metabolic
activity of pulmonary connective tissue (human, hamsters)
P01HL161 18-06 0005 Study of emphysema -
Mechanisms of elastase emphysema (mice)
ROlHL-16437-05 Drug treatment of atherosclerosis
(rabbits, monkeys)
ROlHL-16904-03 Regulation of smooth muscle cells in
arteriosclerosis (rabbit aorta)
ROlHL-2 1303-02 Collagen synthesis by cultured human
vascular cells
R23HL-22383-01 Biosynthesis-Response to oxygen
depletion (human, primates, rats)
CYCLIC AMINO ACIDS, PROLINE,
HYDROXYPROLINE
POlHL-06835-17 0041 Cardiovascular disease - Cardiac
performance in rats with renal hypertension
POlHL-06835-17 0042 Cardiovascular disease -
Myocardial hypertrophy due to renal hypertension (rats)
POlHL-06835-17 0057 Cardiovascular disease - Studies
on cardiac hypertrophy
ROlHL-15478-05 Lipid flux and collagen synthesis in
atherosclerosis (rabbits)
ROlHL-15837-06 Renin and cardiac hypertrophy in
hypertension (rats)
P50HL 17646-04 0005 Study of ischemic heart disease -
Biochemical markers and mediators of myocardial Ischemic
injury
R01HL-187U-04 Cardiovascular matrix-Morphogenesis
and maturation (human, chick embryo, mammaO
ROlHL-19252-02 Vascular connective tissue-Role in
atherosclerosis (rabbits)
POlHL-20993-02 0005 Population dynamics of arterial
cells in atherogenesis - Drugs other than hypolipidemic
drugs affecting atherosclerosis (swine, rabbits)
ROlHL-2 1993-01 Hypertensive hypertrophy-Effects of
cardiac mechanics (rats)
ROIHL 22729-01 Intracellular degradation of newly
synthesized collagen (human, chick, rabbit)
CYCLIC AMINO ACIDS, TRYPTOPHAN
** ROlHL-13645-11 Tryptophan-induced pulmonary
emphysema (cattle, goats, rabbits)
ROlHL-18163-04 Red cell membrane effects due to
oxidizing agents
CYCLIC AMINO ACIDS, TYROSINE
SEE ALSO THYROID HORMONES, THYROXINE
ROlHL-13164-07 Interaction of the alpha and beta chains
of human hemoglobin
CYCLIC AMP
SEE PURINE NUCLEOTIDES, ADENINE NUCLEOTIDES, AMP
CYCLIC
3':5'-CYCLIC-AMP PHOSPHODIESTERASE
SEE NUCLEASES, CYCLIC NUCLEOTIDE PHOSPHODIESTERASE
CYCLIC COMPOUNDS (GENERAL)
SEE CYCLICS (CYCLIC COMPOUNDS) GENERAL
CYCLIC FUNCTIONS, BIOLOGICAL
SEE BIOPERIODICITY, BIOLOGICAL CLOCKS
CYCLIC GMP
SEE PURINE NUCLEOTIDES, GUANINE NUCLEOTIDES, GMP
CYCLIC
CYCLIC KETONES, CYCLOHEXANONES,
KET AMINE
P50HL-14164-07 0042 A/S SCOR-^Iomparative and
experimental atherosclerosis - Comparative cardiology
laboratory (monkeys)
CYCLIC NUCLEOSIDE MONOPHOSPHATES
SEE NUCLEOTIDES, NUCLEOSIDE MONOPHOSPHATES CYCLIC
CYCLIC NUCLEOTIDE PHOSPHODIESTERASE
SEE NUCLEASES, CYCLIC NUCLEOTIDE PHOSPHODIESTERASE
CYCLIC NUCLEOTIDES
SEE NUCLEOTIDES, NUCLEOSIDE MONOPHOSPHATES CYCLIC
CYCLIC PHOSPHODIESTERASE
SEE NUCLEASES, CYCLIC NUCLEOTIDE PHOSPHODIESTERASE
CYCLICS (CYCUC COMPOUNDS) GENERAL
P01HL-03174-23 0011 Mechanisms of acute vascular
reaction to injury - Mutagen metabolism by artery wall in
etiology of atherosclerosis (human, animals)
ROlHL-15447-06 Vascular role of prostaglandin and cyclic
nucleotides (rats)
R01HL-17921-04 Peroxy radicals to prostaglandins in
vessels and lung
ROlHL-20579-02 Synthesis of therapeutically important
alkaloids
ROlHL-20622-02 Pulmonary uptake and accumulation of
drugs (rabbits, rats)
R01HL-21367-02 Polyether ionophores -Synthesis of X537A
and analogs
ROlHL-22219-01 Prostacyclin and peroxides in blood and
membrane disease
CYCLICS, CARBOPOLYCYCLICS
SEE ALSO STEROIDS
R01HL-19654-03 Biochemical-pharmacological evaluation
of lung cells (rabbits)
CYCLICS, CARBOPOLYCYCLICS,
BENZANTHRACENES
P01HL-03174-23 0011 Mechanisms of acute vascular
reaction to injury - Mutagen metabolism by artery wall in
etiology of atherosclerosis (human, animals)
(contd)
*Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojects deschbing specific research aspects.
See Appendix for mvestigator's name and grant number.
CYC
CYCUCS, CARSOPOIYCYCIICS, BENZOPYRENES
POIMl 031/4 ^3 UOll Mec'hanisnu ut nculii vajiulai
reaction to in|uiy Mulige" invlabulism by nitoiy wall in
•tiology of athetoscltroiis (human animals)
P60HL W269 04 00 IS National h«.iil and blood ves»l
rasaatch and damonstiatlon canlei lipupiolmn
matabolism laboiatory (human)
R23HI I%0b01 Lipid fequiiemont ot tha lung mono
oxygenasa system (rabbits)
CYCUCS, CARBOPOIYCYCIICS,
METHYICHOLANTHRENE
POIHL 063/0 1/ 0004 Cardiopulmonary and lenal
pathology research center lymphocytes in graft reiection
■nd immune suiveillance (human)
CYCUCS, CARBOPOIYCYCUCS, PYRENES
ROIHI 16828 04 Gradient and transport ot oxygen in
tissue and organs (mammals)
P60HL 1726904 OOIS National heart and blood vessel
research and demonstiation center - Lipoprotein
metabolism laboraloiy (human)
CYCUCS, HETEROCYCUCS
SEE ALSO NITROARYLS
SEE ALSO PHOSPHOARYLS
ROIHL 18764 03 Biosorbable tbromboresistant surfaces
(dogs. rats, swine, human)
CYCUZATION, DIELS-ALDER REACTION
ROIHL 205/9 02 Synthesis o1 therapeutically important
alkaloids
CYCLOHEPTANES, AMITRIPTYUNE
ROlHL-2271801 Cardiovascular drug interactions-
Metabolism models (dogs)
CYCLOHEPTANES, CYPROHEPTADINE
P01HL1857603 0007 Thrombosis research program
project - Relationships between coagulability and
thrombosis (human, animals)
P01HL1864503 0006 Biology of the artery wall and
atherosclerosis • The platelet and atherosclerosis (monkeys.
baboons)
CYCLOOLEFINS -ALSO SEE APPROPRIATE
CARBOPOLYCYCUCS AND
SEE ALSO BENZENE
ROlHL-2099602 Structural and reactivity of iron and
cobalt complexes
CYCLOPHOSPHAMIDE
SEE HALOALKYUMINES. CYCLOPHOSPHAMIDE
CYCLOTRON
SEE RADIATION, PARTICLE ACCELERATORS
CYNOPITHECUS
SEE MAMMALS. PRIMATES, MONKEYS AND APES
(ANTHROPOIDS, NON-HUMAN), OLDWORLD MONKEYS.
MACACA SP.*
CYPROHEPTADINE
SEE CYCLOHEPTANES, CYPROHEPTADINE
CYPROTERONE (ACETATE)
SEE PROGESTERONE ANALOGS, CYPROTERONE (ACETATE)
CYSTAMINE
SEE AMINO SULFIDES, CYSTAMINE
CYSTATHIONINE SYNTHETASE DEFICIENCY
SEE MHABOLIC DISORDERS INBORN, AMINOACIDOPATHIES.
HOMOCYSTINURIA
CYSTEAAAINE
SEE AMINOTHIOLS, CYSTEAMINE
CYSTEINE
SEE SULFUR AMINO ACIDS, CYSTEINE
CYSTIC FIBROSIS
SEE METABOLIC DISORDERS INBORN, CYSTIC FIBROSIS
CYTOCHALASIN (B)
SEE TOXICOLOGY, MYCOTOXINS, CYTOCHALASIN
CYTOCHEMISTRY
SEE HISTOCHEMISTRY AND CYTOCHEMISTRY (GENERAL)*
CYTOCHROME
SEE HEMOPROTEINS, CYTOCHROME
CYTOCHROME A
SEE HEMOPROTEINS, CYTOCHROME A
CYTOCHROME B
SEE HEMOPROTEINS. CYTOCHROME B
CYTOCHROME B5 OXIDOREDUCTASE
SEE OXIDOREDUCTASES. CYTOCHROME B5 REDUCTASES
CYTOCHROME B5 REDUCTASES
SEE OXIDOREDUCTASES, CYTOCHROME B5 REDUCTASES
CYTOCHROME C
SEE HEMOPROTEINS, CYTOCHROME C
171
CYTOCHROME OXIDASES
Sll OXIOORinUCIASIS. CYIOCHROMt OXIDAStS
CYTOCHROME P450
Sii HtMOI'ROlUNS, CYTOCHROME P4b0
CYTOCUPREINS
SEE MdAllOPROItlNS, CYTOCUPREINS
CYTODIAGNOSIS
Sfl OIAGNOSIIC TESTS, CYTODIAGNOSIS*
CYTOGENETICS
SEE GENETICS, CYTOGENETICS
CYTOLOGY (GENERAL) SEE ALSO CELL...CYTO...*
SEE ALSO CELLS
SEE ALSO GENETICS, CYTOGENETICS
SEE ALSO MOLECULAR CYTOLOGY STUDY SEC'ION
SEE ALSO OPTICS, MICROSCOPY (GENERAL)*
POIHL 18208 04 0002 Center for the study of blood cell
rheology Holography of RBC shape (human)
P50HL 19155-02 0008 Pathophysiology of pulmonary
edema Core microscopy laboratory
P50HL 19156 02 0006 Pulmonary SCOR Chronic diseases
of airways Core microscopy laboratory
P50HL 1918502 0012 Pulmonar/ SCOR Neonatal
respiratory distress syndromes Core microscopy lab
ROlHL-19684-03 Histotypic lung culture in circumfusion
systems (mice)
NOIHR 62930-03 Lung cell resource facility
CYTOLYSING T LYMPHOCYTES
SEE BLOOD CELLS, T LYMPHOCYTES, KILLER
CYTOLYSIS
SEE CELL DESTRUCTION, CYTOLYSIS
CYTOMEGALOVIRUSES
SEE VIRUSES, HERPESVIRUSES. CYTOMEGALOVIRUSES
CYTOPATHOGENIC EFFECT BACTERIAL
SEE BACTERIAL DISEASES. CYTOPATHOGENIC EFFECT
BACTERIAL
CYTOPATHOGENIC EFFECT VIRAL
SEE VIRUS DISEASE CHARACTERISTICS, CYTOPATHOGENIC
EFFECT VIRAL
CYTOPHIUC ANTIBODIES HUMORAL
(CIRCULATING) (SERUM)
SEE HYPERSENSITIVITY. SENSITIZING ANTIBODIES HUMORAL
CYTOPLASM
SEE CELL COMPONENTS. CYTOPLASM
CYTOPLASMIC GRANULES
SEE CELL COMPONENTS. CYTOPUSMIC GRANULES
CYTOSIDE MONOHEXOSIDES
SEE GLYCOSPHINGOLIPIDS. CERAMIDE TRIHEXOSIDES
CYTOSIDES
SEE GLYCOSPHINGOLIPIDS. CERAMIDE OIHEXOSIDES
CYTOSINE ARABINOSIDE
SEE PYRIMIOINE NUCLEOSIDES. CYTOSINE NUCLEOSIDES,
CYTOSINE ARABINOSIDE
CYTOTOXIC T LYMPHOCYTES
SEE BLOOD CELLS. T LYMPHOCYTES, KILLER
CYTOTOXICITY
SEE TOXICOLOGY. CYTOTOXICITY
CYTOXAN
SEE HALOALKYUMINES. CYCLOPHOSPHAMIDE
DACRON
SEE PLASTICS. POLYETHYLENE TEREPHTHALATES
DALMANE
SEE AZEPINES, DIAZEPINES. FLURAZEPAM
DANLOS SYNDROME
SEE METABOLIC DISORDERS INBORN. EHLERS-DANLOS
SYNDROME
DANTRIUM
SEE IMIDAZOLEDIONES. HYDANTOINS. DANTROLENE
DANTROLENE
SEE IMIDAZOLEDIONES. HYDANTOINS. DANTROLENE
DAPSONE
SEE SULFONES, DAPSONE
OARENTHIN
SEE PHENYLALKYLAMINES. BENZYLAMINES. BRETYUUM
TOSYLATE
DARK ADAPTATION
SEE EYE. VISION. DARK ADAPTATION
DARK REPAIR (DNA)
SEE NUCLEIC ACIDS REPAIR, ONA REPAIR (ENZYME)
DATA BANKS
SEE CHEMICAL AND DRUG INFORMATION SYSTEMS
SEE INFORMATION SYSTEMS (INCL BANKS AND CENTERS)
OfA
DATA MANAGEMENT SYSTEMS
511 INIORMAIION MMIW, (INI. I IIANK'. AND (.(NIIM'.l
DATA MONITORING AND REPORTING SYSTIMS
S(l INIOHMAIION '.YMIM', (INM HANK', AND CeNrtflS)
DATA PROCESSING, AUTOMATIC
Sft INIORMAIION AND COMMUNICAIION. AUTOMATIC DATA
PROCISSING
DATA RETRIEVAL
Sf( INFORMATION SYSTfMS, INFORMATION RtlRIEVAl
DATAPHONE
SEE COMPUTER. DATAPHONE
DAUNOBLASTIN
SEE ANTIBIOTICS. OAUNOMYCIN
DAUNOMYCIN
SEE ANTIBIOTICS. DAUNOMYCIN
DAUNORUBICIN
SEE ANTIBIOTICS. DAUNOMYCIN
DDT
SEE PESTICIDES. INSECTICIDES. CHLORINATED
HYDROCARBON INSECTICIDES. DDT
DEAE CELLULOSE CHROMATOGRAPHY
SEE PHYSICAL SEPARATION. CHROMATOGRAPHY, DEAE
CELLULOSE*
DEALKYLATION
SEE ALKYL (GROUPS). ALKYLATION DEALKYUTION
DEAMINASES
SEE AMINOHYOROLASES
DEATH, CADAVER (TISSUE)
ROlHL-23994 01 Biochemical properties of human cardiac
myosin
DEATH, CEREBRAL
ROIHL 2014302 Hypothermic circulatory arrest -Cerebral
vascular change (dogs)
DEATH, POST-MORTEM
ROlHL-01803-23 0005 Arteriosclerosis, glomerulonephritis.
rheumatic fever - Immunologic and dietary synergy in the
pathogenesis of atherosclerosis (rabbits)
ROlHL-01803-23 0010 Arteriosclerosis, glomerulonephritis.
rheumatic fever - Atherosclerosis induction-Graft rejection
and hypercholesterolemia (rabbits)
ROlHL-01803-23 0011 Arteriosclerosis, glomerulonephritis.
rheumatic fever ■ Immunopathologic consequences of
cigarette smoking (human, rabbits, plants)
ROlHL-05694-20 Functional pathology of cardiovascular
disease (human)
** POlHL-10436-13 0009 A mulfidisciplinary study of
congenital heartdisease - Pathophysiology and
morphogenesis of congenital heart disease (human)
P01HL-I2373-10 0016 Cardiopulmonary physiology and
pathophysiology ■ Histology-histochemistty-Gough laboratory
POlHL-13330-08 0056 Mechanical circulatory support •
Blood compatibility linings (calves)
P50HL-14136-07 0004 Pulmonary SCOR-Airways
obstructive diseases - Morphometric studies of developing
emphysema (human)
P50HL-14I36-07 9003
obstructive diseases
P50HL14138-05 0009
Pulmonary SCOR-Airways
Pathology core (human, dogs)
Center for research on
atherosclerosis - Core angiographic-diagnostic laboratory
(human, dogs, birds)
P50HL-U153-07 0019 Johns Hopkins Lung Center-
Chronic diseases of airways • Pathology core (human,
animal)
P50HL-14164-07 0026 A/S SCOR-Comparative and
experimental atherosclerosis - Comparative pathology unit
(pigeons, monkeys)
P50HL-15389-07 0018 Pulmonary SCOR-Hypersensitivity
pneumonitis - Pathology core (human, animal)
P60HL-17269-04 0001 National heart and blood vessel
research and demonstration center - Atherosclerosis-
Arterial pathology and plasma lipids (human)
P60HL-17269-04 0048 National heart and blood vessel
research and demonstration center - Atherosclerosis-
Lipoproteins and the arterial wall (human)
P60HL- 17 292-04 0003 Vermont Lung Center - Subclinical
pulmonary disease in a rural environment (human)
P50HL-17646-04 0003 Study of ischemic heart disease -
Core pathology facility (human, dogs)
P50HL-17648-04 0020 Study of ischemic heart disease ■
Core pathology laboratory-lschemic heart disease (human.
animal)
P50HL- 17648-04 0021 Study of ischemic heart disease -
Biventricular contractile responses to acute myocardial
infarction (mammals)
P50HL-1 7655-04 0010 Study of ischemic heart disease -
Core facility-Cardiovascular pathology (human, animal)
P50HL-17665-04 0028 Study of ischemic heart disease -
Pathologic and biochemical studies of ischemic
myocardium (human, dog)
P50HL-17667-04 0045 Study of ischemic heart disease •
Pathology of myocardial ischemic necrosis (human)
(contd)
*E>£lijd«: routine methodokigy OR covers only general projects which preclude indexing at the specific level.
**Oriented significantly to above subject.
M Grant has subprojccts descnbing specific research aspects.
See Appendix for investigator's name and grant number.
DEA
172
DES
P50HL-17669-04 0022 Ischemic heart disease center
(SCOR) i Pathological studies of human and experimental
ischemic heart disease
P50HL-17670-04 0016 Study of ischemic heart disease ■
Core pathology laboratory (human, dogs, monkeys)
P50HL-1768204 0012 Study ot ischemic heart disease ■
Pathology core laboratory (human)
ROlHL-18793-03 Clinical-pathologic studies of sudden
cardiac death (human)
ROlHL-18805-04 0007 Sudden cardiac death and the
onset of myocardial infarction - Analysis of pathologic
factors involved in sudden death (human)
P50HL19362-02 0015 A/S SCOR -Atherosclerosis in
nonhuman primates - Core laboratory-Pathology and
morphometry (baboons)
ROlHL-20500-02 Diabetic human brain microvascular
basement membrane (human)
ROlHL-20895-03 0006 Cineangiographic studies of
cardiovascular system - Cardiomyopathy-Hemodynamic,
radiologic, morphologic abnormalities (dog. rabbit)
R01HL-20895-D3 0007 Cineangiographic studies of
cardiovascular system - Determinants of collateral
formation (dogs, hamsters)
ROlHL-21684-02 0003 Radionuclide infarctsizing and
therapy evaluation - Core pathology laboratory (dogs,
human)
DEATH CERTIFICATES, MORTALITY DATA
SEE POPULATION STUDIES HUMAN, MORTALITY
DEBRANCHER DEFICIENCY GLYCOGENOSIS
SEE METABOLIC DISORDERS INBORN, GLYCOGENOSIS. TYPE
III
DECARBOXYLASES, AMINO ACID
DECARBOXYLASES
ROlHL-21 105-02 Organ specific drugs -Cardiovascular and
renal effects (dogs)
DECARBOXYLASES, HISTIDINE DECARBOXYLASE
POlHL-14388-07 0187 Regulation of the circulation in
pathological states - Histamine and circulatory control
ROlHL-19830-02 Shear to aortic histamine synthesis and
permeability (dogs)
ROlHL-20460-03 Aortic histamine synthesis in diabetes
(rat)
POlHL-22602-01 0003 Pathophysiology of the
endothelium - Mechanisms of endothelial proliferation
(human, animals)
DECARBOXYLASES, ORNITHINE
DECARBOXYLASE
P50HL-19157-02 0009 Studies in cystic fibrosis and
bronchiolitis - Polyamine metabolism in cystic fibrosis
(human, rat)
** POlHL-20984-02 0006 Cellular mechanisms in cardiac
hypertrophy - Early biochemical aspects of cardiac
hypertrophy (rats)
** R23HL-21234-02 The regulation of cardiac hypertrophy
(rabbits)
DECARBOXYLASES INHIBITORS
SEE ENZYME INHIBITORS, DECARBOXYLASES INHIBITORS
DECELERATION
SEE ENVIRONMENT, GRAVITY-MOTION
OECEREBRATION
SEE BRAIN LESIONS SURGICAL, OECEREBRATION
DECISION MAKING
SEE PSYCHOLOGY, COGNITION, DECISION MAKING
DECISION MAKING, BIOMEDICAL RESEARCH
PROGRAM EVALUATION
SEE HEALTH SCIENCES RESEARCH ANALYSIS-EVALUATION-
PLANNING
DECISION MAKING, COMPUTER ASSISTED
MEDICAL DECISION MAKING
SEE BIOMEDICAL SYSTEMS AUTOMATED, COMPUTER
ASSISTED MEDICAL DECISION MAKING
DECISION MAKING, EDUCATION PROGRAMS
(SYSTEMS) EVALUATION-PLANNING
SEE EDUCATION PROGRAMS (SYSTEMS) EVALUATION-
PLANNING
DECISION MAKING, HEALTH CARE EVALUATION
SEE HEALTH CARE (SERVICES)(RESOURCES) ANALYSIS AND
EVALUATION
DECISION MAKING, HEALTH CARE PLANNING
SEE HEALTH CARE (SERVICES)(RESOURCES) PLANNING
DECOMPRESSION
SEE ENVIRONMENT, ATMOSPHERIC PRESSURE,
COMPRESSION-DECOMPRESSION
DECOMPRESSION SICKNESS
SEE INJURIES, DYSBARISM
DEEP SEA DIVING
SEE WATER ENVIRONMENT. DIVING AND SWIMMING
DEEP VEIN THROMBOSIS
SEE CARDIOVASCULAR DISORDERS, THROMBOSIS, VENOUS
DEFENSE MECHANISMS
SEE PSYCHOLOGY, DEFENSE MECHANISMS
DEFEROXAMINE
SEE IRON, FEROXAMINE-DEFEROXAMINE
DEFIBRILLATION ELECTRICAL
SEE HEART RESUSCITATION, ELECTRIC COUNTERSHOCK
DEFIBRILLATORY AGENTS
SEE CARDIOVASCULAR AGENTS, ANTIARRHYTHMIC AGENTS
DEGLUTITION
SEE GASTROINTESTINAL FUNCTION, DEGLUTITION
DEHYDRASES
SEE DEHYDRATASES
SEE OXIDOREDUCTASES, DEHYDROGENASES
DEHYDRATASES
ROlHL-02477-23 Biosynthesis and function of lipids
(microorganisms, rats)
DEHYDRATASES, CARBONIC ANHYDRASE
POlHL-06285-18 0198 Cardiovascular respiratory
physiology and bioche'nistry - Renal tubular secretion of
hydrogen ion (animals)
ROlHL-14131-18 Abnormal hemoglobin syndromes
(human)
ROlHL-15026-12 Quantitative genetic control of protein
synthesis (human, primates, mammals)
ROlHL-16059-06 Structure and function of serum
lipoproteins (cattle, human)
" ROlHL-17963-04 Human erythrocyte carbonic anhydrase
POlHL-18577-03 0005 Lipoproteins -Cell surface
interactions - Chemical synthesis of apolipoproteins and
apoliprotein fragments
** ROlHL-18905-04 Acquisition of native conformation of
proteins (human, cattle)
ROlHL-19008-02 Carbon dioxide diffusion in lung and
muscle tissues (dogs)
POlHL-19737-02 0005 Cellular and molecular aspects of
respiratory physiology - Interaction of respiratory exchanges
and blood gas parameters (human, animals)
POlHL-19737-02 0008 Cellular and molecular aspects of
respiratory physiology - Kinetics of movement of acid
metabolites from cell to capillary blood (dogs)
POlHL-19737-02 0011 Cellular and molecular aspects of
respiratory physiology - Chemical and metabolic factors on
peripheral chemoreceptor activity (cats)
** ROlHL-22258-01 New aspectsof pharmacology related to
carbonic anhydrase
DEHYDRATION, BODY FLUIDS
SEE BODY FLUID BALANCE, BODY WATER, DEHYDRATION
DEHYDRATION REACTIONS
SEE CHEMICAL REACTIONS. HYDRATION, DEHYDRATION
DEHYDROEPIANDROSTERONE
SEE ANDROSTANE SERIES. DEHYDROEPIANDROSTERONE
DEHYDROGENASES
SEE OXIDOREDUCTASES. DEHYDROGENASES
DEIODINATION
SEE HALOGENATION, lODINATION-DEIODINATION
DELAYED ACTION PREPARATIONS
SEE DOSAGE FORMS
DELAYED HYPERSENSITIVITY
SEE HYPERSENSITIVITY, DELAYED HYPERSENSITIVITY
DELETION, CHROMOSOME
SEE GENETICS, MUTATION, CHROMOSOME MUTATION,
DELETION
DELIVERY
SEE PREGNANCY, BIRTH
DELIVERY OF HEALTH CARE
SEE HEALTH CARE SERVICES, PATIENT CARE MANAGEMENT
DEMECOLCINE
SEE ALKALOIDS, DEMECOLCINE
DEMENTIA SENILE
SEE BRAIN DISORDERS, CEREBRAL ATROPHY DIFFUSE,
SENILE DEMENTIA
DEMETHYLATION
SEE ALKYL (GROUPS), DEMETHYLATION
DEMOGRAPHY
SEE POPULATION STUDIES HUMAN, DEMOGRAPHY
DEMONSTRATION PROJECTS
SEE HEALTH SERVICES DEMONSTRATION PROJECTS
DEMYELINATION AND DEMYELINATING
DISORDERS
SEE NERVOUS DISORDERS, MYELINOPATHIES (GENERAL)
DENATURATION
SEE PROTEINS DENATURATION
DENERVATION
SEE NEUROSURGERY, DENERVATION (GENERAL)
DENGUE
SEE VIRUS DISEASES, ARBOVIRUS. DENGUE
DENIAL AS A DEFENSE MECHANISM
SEE PSYCHOLOGY. DEFENSE MECHANISMS. DENIAL
DENSITOMETRY
SEE PHYSICAL PROPERTIES. DENSITOMETRY*
DENSITY (SPECIFIC GRAVITY)
SEE PHYSICAL PROPERTIES. DENSITY (SPECIFIC GRAVITY)
DENSITY, ELECTRON
SEE ELECTRON CHARGE DISTRIBUTION
DENSITY, OPTICAL
SEE PHYSICAL PROPERTIES. DENSITOMETRY*
DENSITY-GRADIENT ULTRACENTRIFUGATION
SEE PHYSICAL SEPARATION. ULTRACENTRIFUGATION. DENSFTY
GRADIENT*
DENTAL DEVELOPMENT
ROlHL-11153-12 Quantitation of flow and solute flux in
microvessels (cats, rats)
DENTAL STRUCTURE, GINGIVA
ROlHL-11153-12 Quantitation of flow and solute flux in
microvessels (cats, rats)
DEOXYCHOLATES
SEE CHQLANATE SERIES. DEOXYCHOUTES
DEOXYCORTICOSTERONE
SEE ADRENAL CORTEX HORMONES. DEOXYCORTICOSTERONE
1 1 -DEOXY- 1 7-HYDROXYCORTICOSTERONE
SEE ADRENAL CORTEX HORMONES. ll-DEOXY-17-
HYDROXYCORTICOSTERONE
DEOXYRIBONUCLEASE
SEE NUCLEASES. DEOXYRIBONUCLEASE
DEOXYRIBONUCLEATE S'-
OLIGONUCLEOTIDYLHYDROLASE
SEE NUCLEASES. DEOXYRIBONUCLEASE
DEOXYRIBONUCLEIC ACID POLYMERASE
SEE NUCLEOTIDYLTRANSFERASES. DNA
NUCLEOTIDYLTRANSFERASES
DEOXYRIBONCULEIC ACID(S)
SEE NUCLEIC ACIDS. DNA
DEOXYRIBONUCLEIC ACID(S) REPLICATION
SEE NUCLEIC ACIDS SYNTHESIS. DNA
DEOXYRIBONUCLEOSIDE MONOPHOSPHATES
CYCLIC
SEE NUCLEOTIDES. DEOXYRIBONUCLEOSIDE
MONOPHOSPHATES CYCLIC
DEOXYRIBONUCLEOSIDE TRIPHOSPHATE DNA
NUCLEOTIDYL TRANSFERASE
SEE NUCLEOTIDYLTRANSFERASES, DNA
NUCLEOTIDYLTRANSFERASES
DEOXYTHIOGUANOSINE
SEE THIOPURINE NUCLEOSIDES, THIOGUANINE NUCLEOSIDES,
DEOXYTHIOGUANOSINE
DEPENDENCY, EMOTIONAL
SEE PSYCHOLOGY, EMOTIONAL DEPENDENCY-INDEPENDENCY
DEPOLARIZING AGENTS NEUROMUSCULAR
SEE MUSCLE RELAXANTS, NEUROMUSCULAR BLOCKING
AGENTS DEPOURIZING
DEPOLYMERIZATION
SEE MOLECUUR CONDENSATIONS, POLYMERIZATION-
DEPOLYMERIZATION
DEPRESSANTS (APPETITE)
SEE NUTRIENT INTAKE ACTIVITY, APPETITE DEPRESSANTS
DEPRESSION
SEE PSYCHOLOGY, EMOTIONS, DEPRESSION
DEPRESSION, REACTIVE PSYCHOTIC
SEE PSYCHOSIS, DEPRESSIVE, REACTIVE PSYCHOTIC
DEPRESSION
DEPRIVATION
SEE PSYCHOSOCIAL ISOUTION-OEPRIVATION
DEPTH INTOXICATION
SEE INJURIES, DYSBARISM, INERT GAS NARCOSIS
DERMATAN SULFATE
SEE POLYSACCHARIDES, GLYCOSAMINOGLYCANS, DERMATAN
SULFATE
DESENSITIZATION FOR HYPERSENSITIVITY
SEE HYPERSENSITIVITY DESENSITIZATION
DESENSITIZATION PSYCHOTHERAPY
SEE PSYCHOTHERAPY, DESENSITIZATION
DESFERRIOXAMINE
SEE IRON, FEROXAMINE-DEFEROXAMINE
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
•'Oriented significantly to above subiect.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
DES
DESIGN OF COMPUTERS
sn COMPUIIR. OtSIC.N AND EVALUATION OF COMPUTERS
(INCl HARDWARi)
DESIPRAMINE
Sll A/lPINfS. DESIPRAMINf
DESMOSOMES
SEE CELL CELL INTERACTION, INTERCELLULAR CONNECTIONS
JUNCTIONS
DETACHED RETINA
Sff LYE niSORDLRS. RETINA ANO CHOROID DISORDERS.
REIINA DETACHMENT
DETERGENTS
Sff PHYSICAL PROPERTIES. SURFACTANTS, DETERGENTS
OETOXICATION
SEE TOXICOLOGY. TOXICANT METABOLISM. OETOXICATION
DETROTHYRONINE
SEE THYROID HORMONES. DEXTROTHYROXINE
DEVELOPMENT
SEE CELL DIFFERENTIATION
SEE CHILD DEVELOPMENT (NON-PSYCHOLOGICAL)
SEE EMBRYOLOGY
SEE GROWTH ANO DEVELOPMENT
DEVELOPMENTAL BEHAVIORAL SCIENCES STUDY
SECTION
SEE BEHAVIORAL SCIENCES (DEVELOPMENTAL) STUDY
SECTION
DEVELOPMENTAL DISORDERS (INTRAUTERINE
FAILURE TO THRIVE)
SEE PREGNANCY DISORDERS. EMBRYO-FaAL GROWTH
DEVELOPMENT DISORDERS (SEE ALSO APPROPRIATE
SPECIFICS)
DEVELOPMENTAL NUTRITION (GENERAL)
SEE NUTRITION. DEVELOPMENTAL NUTRITION
DEVELOPMENTAL PHARMACOLOGY (DRUG
ADVERSE EFFECTS FETAL)
SEE PREGNANCY. EMBRYO-FETUS DRUGS ADVERSE EFFECTS
DEVELOPMENTAL PSYCHOLOGY (CHILD MENTAL
DEVELOPMENT)
SEE CHILD MENTAL DEVELOPMENT
DEXAMETHASONE
SEE ADRENAL CORTEX HORMONES ANALOGS.
DEXAMETHASONE
DEXEDRINE
SEE PHENYLALKYLAMINES. D-AMPHETAMINE
DEXTRAN
SEE HEXOSANS. GLUCANS. DEXTRAN
DEXTROAMPHETAMINE
SEE PHENYLALKYLAMINES. D-AMPHETAMINE
DEXTROTHYROXINE
SEE THYROID HORMONES, DEXTROTHYROXINE
DFP
SEE PHOSPHATES, FLUOROPHOSPHATES, DFP
DIABETES (INCLUDING NON-INBORN CASES)
SEE CARBOHYDRATES METABOLISM DISORDERS, DIABCTES
DIABETES, JUVENILE
SEE CARBOHYDRATES MCTABOLISM DISORDERS, DIABETES.
JUVENILE
DIABETES BRONZE
SEE MHABOLIC DISORDERS INBORN. HEMOCHROMATOSIS
DIABETES IN PREGNANCY
SEE CARBOHYDRATES METABOLISM DISORDERS, DIABETES
IN PREGNANCY
DIABETES INSIPIDUS
SEE METABOLIC DISORDERS (INBORN), DIABETES INSIPIDUS
DIABETES MELLITUS
SEE CARBOHYDRATES METABOLISM DISORDERS, DIABETES
DIABETIC ACIDOSIS
SEE CARBOHYDRATES METABOLISM DISORDERS, DIABETIC
ACIDOSIS
DIABETIC ANGIOPATHIES
SEE CARBOHYDRATES METABOLISM DISORDERS, DIABETIC
ANGIOPATHIES
DIABETIC NEPHROPATHIES
SEE CARBOHYDRATES METABOLISM DISORDERS, DIABETIC
NEPHROPATHIES
DIABETIC NEUROPATHIES
SEE CARBOHYDRATES METABOLISM DISORDERS, DIABETIC
NEUROPATHIES
DIABETIC RETINOPATHY
SEE CARBOHYDRATES METABOLISM DISORDERS, DIABETIC
RaiNOPATHY
173
DIACYLOIYCEROL LIPASE
Sll lll'ASIS, lIPdI'ROIIIN UPAS!
DIAOIC INTERACTION
Sll PSYCIIOIOCY SOCIAL INTERPERSONAL RELATIONS.
DIADIC INIIRACIION
DIAGNOSTIC ACCURACY
Sll diac.nosik; quaiiiy standards
DIAGNOSTIC ERRORS
Sfl DIAGNOSTIC QUALITY STANDARDS
DIAGNOSTIC PROCEDURES SAFETY
SEE DIAGNOSTIC QUALITY STANDARDS, DIAGNOSTIC
PROCEDURES SAFETY
DIAGNOSTIC QUALITY-STANDARDS
M P01HL07?93W Non invasiuc cardiovascular
measurements
** P01HL07293 17 0049 Noninvasive cardiovascular
measurements Cardiac scanner engineering evaluation
and error analysis
** P01HL07293 17 OOM Non invasive cardiovascular
measurements Cardiac dimensions measurements
engineering evaluation and error analysis
** P01HL07293 17 0051 Non invasive cardiovascular
measurements Physiologic evaluation of duplex scanner
(dogs)
** POlHL-07293 17 0052 Non invasive cardiovascular
measurements - Clinical evaluation of the duplex scanner
(human)
** P01HL0729317 0053 Non invasive cardiovascular
measurements Clinical evaluation of cardiac dimensions
using the duplex scanner (human)
P01HL07293 17 0055 Non invasive cardiovascular
measurements Peripheral vascular transducer position
locating system
** P01HL-07293-17 0057 Noninvasive cardiovascular
measurements - Peripheral vascular scanner engineering
evaluation and error analysis (human)
** POlHL-07293-17 0058 Non-invasive cardiovascular
measurements - Peripheral duplex scanner physiologic
evaluation
POlHL-07293-17 0059 Non-invasive cardiovascular
measurements - Intracardiac blood flow measurement
(human)
POlHL-10436-13 0001 A multidlsciplinary study of
congenital heart disease - Assessment of the outlook for
children with congenital heart disease
P01HL10539-12 0064 Pathophysiology of circulation
Exercise physiology and pathophysiology (human)
** ROlHL-10582-12 Thrombosis and hemostasis-Analysis,
methods and standards (human, cattle, venom)
P01HL-12738-10 0127 Physiologic pharmacology and its
clinical applications - Cardiac electrical activity (human,
animals)
P01HL-13108-09 0002 Clinical heart transplantation •
Preoperative immunologic studies of cardiac recipients
P50HL-14136-07 0005 Pulmonary SCOR-Airways
obstructive diseases - Radiographic studies of airways
obstructive disease (human)
** R01HL14785-07 Ultrasonic scattering for tissue
characterization (dogs, cattle, human)
** P50HL-15092-07 0013 Immune and fibrotic response to
occupational environments - Epidemiology core resource
P50HL-1510307 0001 A/S SCOR-Early natural history of
arteriosclerosis ■ Clinical research-Bogalusa heart study
(children)
P60HL-15160-07 0013 Center for sickle cell disease ■
Immunochemical diagnosis of hemoglobinopathies (infants)
P01HL-15194-07 0025 Pathophysiology of
cardiopulmonary dysfunction - Myoglobinemia as an index
of myocardial ischemia and infarction
POlHL-15265-05 0003 Program on surgical control of the
hyperlipidemias - Central lipid laboratory
POlHL-15265-05 0012 Program on surgical control of the
hyperlipidemias - Central arteriography-Radiography
laboratory (human)
" ROlHL-16292-05 0020 Surgery and non-obstructive
coronary insufficiency - Limitation of transthoracic EGG in
detecting subendocardial ischemia (dogs)
" ROlHL-16784-03 Lung tissue and water volume (human,
dogs)
ROlHL-17578-04 Exercise performance in children with
heart disease
P50HL-17648-04 0018 Study of ischemic heart disease -
Myocardial damage-Infarction vectors recalled by
premature atrial stimulation
P50HL-I7648-04 0033 Study of ischemic heart disease ■
Data management-Electrocardiographic analysis system
P50HL-17665-04 0005 Study of ischemic heart disease -
Evaluation of zone of jeopardized myocardium in patients
with angina pectoris
P50HL-17665-04 0027 Study of ischemic heart disease -
Positron imaging of regional myocardial perfusion (human,
dog)
P50HL-17667-04 0043 Study of ischemic heart disease -
Quantitation of myocardial infarct size by serial enzyme
measurements (human)
** P50HL- 176 70-04 0005 Study of ischemic heart disease -
Quantitative assessment of the vectorcardiogram (human)
P50HL 17670-04 0015 Study of ischemic heart disease -
Radionuclide studies of myocardial ischemia (human)
P50HI 17687 04 DOOR Study ol lulwmlc haari (li>»»
Clinical con unit
P50HI I/6M2U4 0011 Study of i>ch«mic hvarl diiMM
Nuclnar medirini! core unit (human, dogt. rabbili. mlc«)
ROIHL 17/26 03 Baclarial heparinau in diagnotlic
coagulation ^tudie^
Oxygen delivery lo li\)ue (rat. do|)
Normalized body ^urlar.e potential mapi
Cardiovascular lollow up ol hyperteniivt
ROIHI 17826 04
ROIHI 17931 04
(children)
HUIHI 18456 03
adolescents
ROIHI 18783 04 Detection and control ol venliiculiii
premature beats (human)
ROIHI 18805 04 0001 Sudden cardiac death and the
onset o( myocardial inlarction Prcdulive value ol
maximum exercise stress testing (human)
ROIHL 18850-03 Classification code for Frank orthogonal
ECO
ROIHL 19095 03 Laser spectroscopy ol lipoproteins
(human)
P50HL 19153 02 0006 SCOR Pulmonary edemas Eitology.
pathogenesis Pulmonary vascular abnormalities in human
lung diseases
P50HL 19156 02 0002 Pulmonary SCOR -Chronic diseases
of airways Early detection of emphysema and chronic
airway obstruction (human, dog)
P50HL 19156 02 0003 Pulmonary SCOR Chronic diseases
of aimvays Powdered tantalum to study airway morphology
and mucociliary clearance (human)
P50HL-19171 02 0005 Pulmonary SCOR Lung in)ury by
childhood infections Chronic respiratory disease of
children in North Carolina
ROIHL 19451-03 0003 Functional characteristics of the
left heart Left ventricular segmental contraction (human,
dogs)
POlHL-19717-02 0046 Response of the lung to injury ■
Bioengineering section
ROIHL 20351 02 A self calibrating in vivo blood gas
monitor (dogs, infants)
ROlHL-20815-02 Validation of indirect tests of small
airways function (human, dogs, ponies)
ROlHL-2083502 Signal analysis of turbulence study in
blood
ROlHL-20895-03 Cineangiographic studies of
cardiovascular system
ROlHL-20895-03 0001 Cineangiographic studies of
cardiovascular system - Videodensitometry and valvular
regurgitation (human, dogs)
ROlHL-20895-03 0002 Cineangiographic studies of
cardiovascular system ■ Coronary disease-Regional
myocardial blood flow (human, dog)
ROlHL-2089503 0003 Cineangiographic studies of
cardiovascular system - Densitometry in coronary stenosis
(human)
ROlHL-20895-03 0004 Cineangiographic studies of
cardiovascular system - Cineangiography-Coronary lesions
and ventricular function (human)
ROlHL-20895-03 0005 Cineangiographic studies of
cardiovascular system - Computerized axial tomography-
Cardiac wall motion and infarction (dogs)
ROlHL-20895-03 0006 Cineangiographic studies of
cardiovascular system - Cardiomyopathy-Hemodynamic,
radiologic, morphologic abnormalities (dog. rabbit)
P50HL-21006-02 0005 Specialized center of research in
arteriosclerosis - Regional myocardial perfusion in patient
with coronary artery disease (also dogs)
ROlHL-21278-01 Abnormal cardiac wall motion viewed
ultrasonically (human, dogs, phantoms)
R01HL-21518-01 Improvement in regional ventilation-
perfusion resolution (human)
* ROlHL-21684-02 0004 Radionuclide infarct sizing and
therapy evaluation - Image analysis-Kinetics of infarction,
ventricular function (human, animal)
* ROlHL-2 1684-02 0005 Radionuclide infarct sizing and
therapy evaluation ■ Clinical evaluation of radioisotope
imaging methods for quantifying infarct size
* ROlHL-21690-02 Sequential multinuclide study of acute
infarction (human, dogs)
ROlHL-21706-02 Nuclear magnetic resonance and
myocardial ischemia (rats)
ROlHL-21707-01 Quantification of infarct size by emission
tomography (human, dogs)
ROlHL-21710-01 Electrocardiographic methods of
quantifying infarct size (human, dogs)
ROlHL-21719-01 Computed cardiac tomography in infarct
sizing (dogs, human)
'* R01HL-21750-02 Electrocardiographic quantification of
infarct size (dogs, human)
t ROlHL-21751-02 Thallium and antimyosin in ischemia and
infarction
'* ROlHL-21751-02 0003 Thallium and antimyosin in
ischemia and infarction - Human studies-Ischemia and
infarction
'• ROlHL-21793-02 Functional infarct size by gated
radioangiography (human, dogs)
'* R01HL-22413-01 Enhanced detection of bubbles in
Doppler flow signals (human)
R23HL-22787-01 Cardiac volume by biplane
echocardiography (human)
'* ROlHL-22852-01 Diagnostic techniques in venous
thromboembolism (human)
(contd)
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
**Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
DIA
174
DIA
ROlHL-22893'01 Evaluating arterial disease by velocity-
wave analysis (dogs, human)
** ROlHL-2295201 Validation of quantitative coronary
arteriography (dogs)
ROlHL-22976-01 Nonuniform ventilation and diffusing
capacity (human)
** NOlHR-3290009 Pilot study to standardize the
measurement of 'closing volume' (human)
** NOlHR-32902-07 Pilot study to standardize the
measurement of closing volume (human)
** NOlHR-32903-11 Pilot study to standardize the
measurement of 'closing volume' (human)
** NOlHR-6290104 Measure pulmonary function in infants
and children (also dogs, rabbits)
NOlHR-62920-02 Noninvasive diagnosis of pulmonary
hypertension (dog, human)
** NOlHR-72920-01 Identify and quantify cystic fibrosis
factors (human)
NOlHV-22917-11 Lipid research clinic (human)
DIAGNOSTIC QUALITY-STANDARDS,
DIAGNOSTIC PROCEDURES SAFETY
SEE ALSO BIOMEDICAL ENGINEERING, MEDICAL EQUIPMENT
SAFETY
SEE ALSO DIAGNOSTIC TESTS, NON-INVASIVE*
ROlHL-00487-29 Vasomotor tone and venous return
(human, dogs, monkeys )
ROlHL-14645-07 Blood flow measurement by ultrasonic
catheter tip methods (human, dogs)
R01HL-1880S-04 0003 Sudden cardiac death and the
onset of myocardial infarction - Prediction from clinical and
laboratory assessments (human)
P50HL-19156-02 0003 Pulmonary SCOR-Chronic diseases
of airways • Powdered tantalum to study airway morphology
and mucociliary clearance (human)
ROlHL-21751-02 0003 Thallium and antimyosin in
Ischemia and infarction Human studies-Ischemia and
infarction
*■* P60HL23282-01 0001 Comprehensive hospital/community
sickle cell center - Fetoscopy for intrauterine diagnosis of
hemoglobinopathy (human, monkeys)
DIAGNOSTIC SERVICES
** P60HL-1 5160-07 0012 Center for sickle cell disease -
Core laboratories
DIAGNOSTIC SERVICES, MASS SCREENING
NOlHB-62908-07 Maternal to infant transmission of
hepatitis B (human)
POlHL-06296-18 0002 Cardiovascular and pulmonary
adaptation to stress - Respiratory muscle blood flow,
mechanics and metabolism (human, dog)
POlHL-09011-15 0018 A research and resource program
in blood - Hepatitis 6 in normal populations-Epidemiology,
risk factors and transmission
** ROlHL-1 1901-12 0009 Effects of metabolic surgery on
the hyperlipidemias - Cholesterol cord blood and family
management program
ROlHL-13654-08 Antilipemic regimes in peripheral
arteriosclerosis (human)
P50HL-14230-07 0088 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Coronary risk factors in school children -
The Muscatine study
P50HL15103-07 0001 A/S SCOR -Early natural history of
arteriosclerosis - Clinical research -Bogalusa heart study
(children)
** P60HL15157-07 0001 Comprehensive center for sickle
cell disease - Screening program (human)
M P60HL-1516007 Center for sickle cell disease
P60HLI5160-07 0003 Center for sickle cell disease -
Genetic counseling in hemogloblnopathies-Dlmensions,
effectiveness
P60HL1 5 160-07 0013 Center for sickle cell disease -
Immunochemical diagnosis of hemoglobinopathies (infants)
** P60HL-15160-07 0017 Center for sickle cell disease -
Demonstration-Education, screening, counseling, patient
care
P60HL-1 5 162-07 0010 Comprehensive sickle cell center -
Core program -Community outreach and education program
** P60HL-15162-07 0011 Comprehensive sickle cell center -
Core program -Genetic counseling and diagnostic screening
P60HL-15162-07 0018 Comprehensive sickle cell center ■
Biochemical and genetic studies of sickle cell anemia
(human)
** P60HL-I5168-07 0001 Comprehensive sickle cell disease
center - Screening program (human)
*• P60HL 15168-07 0010 Comprehensive sickle cell disease
center - Sickle cell center project (children)
** P60HL-15169-05 0019 Support for center for sickle cell
disease Central screening and reference laboratory
P60HL-15169-05 0021 Support for center for sickle cell
disease - Multidisciplinary module system for education,
screening and counseling
" P60HL 15170-05 0002 Support for center for sickle cell
anemia • Adult services -Testing programs
** P60HL-15170-05 0007 Support for center for sickle cell
anemia ■ Pediatric services -Screening program
** POIHL 15265-05 0003 Program on surgical control of the
hyperlipidemias • Central lipid laboratory
*' POIHL 15265-05 0013 Program on surgical control of the
hyperlipidemias - Clinical center Minnesota
** POIHL 1526505 0014 Program on surgical control of the
hyperlipidemias - Arkansas clinical center
ROlHL-15808-06 Role of angiotensinogen in hypertension
and stroke (human, rabbits)
P60HL-1599606 0007 Cincinnati comprehensive sickle
cell center - Screening and counseling
P60HL 15999-05 0004 Miami comprehensive sickle cell
center - Education, screening and counseling
P60HL-16008-06 0001 W/ayne State University
comprehensive sickle cell center - Patient care system
(children, adults)
P60HL- 16008-06 0011 VKayne State University
comprehensive sickle cell center - Education, screening and
counseling
P60HL-17265-04 0001 Community blood resource center
support - Demonstration and evaluation
ROlHL-17364-04 'Big renin' -Biochemical and clinical
studies (human)
ROlHL-17465-04 Beta-thalassemia screening and genetic
counseling
P50HL-1832304 0035 SCOR hypertension center - Control
of high blood pressure at the work site
ROl ML- 184 56-03 Cardiovascular follow-up of hypertensive
adolescents
ROIHL 1877604 Prevention of acute and fatal
cardiovascular disease (human)
ROlHL-18850-03 Classification code for Frank orthogonal
ECG
ROlHL-18977-03 Non-invasive diagnosis of peripheral
arterial disease (human, dogs)
P50HL19171-02 0005 Pulmonary SCOR -Lung injury by
childhood infections - Chronic respiratory disease of
children in North Carolina
ROlHL-19255-03 Evaluation of diagnostic clinical
hemorrheology (human)
P01HL19717-02 0039 Response of the lung to injury -
Lung scanning in alveolitis and asbestolic interstitial
pneumonia (human, animal)
POlHL-19717-02 0046 Response of the lung to injury -
Bioengineering section
ROlHL-20751-01 High speed liquid chromatography of
hemoglobins (human)
P60HL-20985-01 0009 Northern California sickle cell
center - Patient services (children, adults)
P60HL-20985-01 0010 Northern California sickle cell
center - Prenatal diagnosis of sickle cell anemia
ROlHL-21 156-02
lung disease
ROlHL-222 12-01
control program
ROlHL-22380-01
ROlHL-22604-01
studies (human)
ROlHL-22802-01 A rural mining community hypertension
control project (human)
' ROlHL-22821-01 A routine screening analysis for
myoglobinemia
ROlHL-22838-01
children
P60HL-23282-01
cell center
' P60HL-23282-01 9001 Comprehensive hospital/community
sickle cell center - Core -Institutionalization of education,
screening and counseling
P60HL-2328201 9002 Comprehensive hospital/community
sickle cell center - Core-Model sickle cell service for
neighborhood health centers
NO lHR-329 00-09 Pilot study to standardize the
measurement of 'closing volume' (human)
NOlHV-12434-11 Therapy for hypertension in the general
population
NOlHV-12435-15 Therapy for hypertension in the general
population (human)
* NOlHV-12436-15 Hypertension therapy in the general
population (human)
N01HV12440-14 Therapy for hypertension in the general
population (human)
' N01HV-12442-I4 Therapy for hypertension In the general
population (human)
NOlHV-229 17-11
NOlHV-22938-11
population
NOlHV-2293912
program center
NOlHV-22945-11 Cooperative hypertension detection and
follow-up study (human)
N01HV-22971-07 Prevention of coronary heart disease
(human)
NOlHV-22976-07 Multiple risk factor intervention trial.
prevention of coronary heart disease
NOlHV-22977-08 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22979-07 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22980-06 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22981-10 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22982-07 Intervention trial for prevention of
coronary heart disease (human)
NOlHV-22983-07 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-33101-06 Development and conduct of a multiple
risk factor intervention trial (human)
Antitrypsin and other causes of chronic
Alameda county high blood pressure
Detroit hypertension control program
Non-invasive system for arteriosclerosis
Post-transfusion hepatitis in newborn
Comprehensive hospital/community sickle
Lipid research clinic (human)
Therapy for hypertension in general
Hypertension detection and follow-up
NOlHV-33105-09 Intervention trial for prevention of
coronary heart disease (human)
NO lHV-33 106-06 Intervention trial for the prevention of
coronary heart disease (human)
** NOlHV-33108-04 Prevention of coronary heart disease
(human)
NO IHV'33 109-04 Intervention trial for the prevention of
coronary heart disease (human)
NO lHV-33 110-04 Prevention of coronary heart disease
(human)
NOlHV-42929-08 Risk factor intervention trial for the
prevention of CHD (human)
NOlHV-42930-09 Risk factor intervention trial for the
prevention of CHD (human)
NOlHV-42931-07 Risk factor intervention trail for the
prevention of CHD (men)
NOlHV-42932 05 Risk factor intervention trial for the
prevention of CHD (human)
NOlHV-42933-09 Multiple risk factors in coronary heart
disease (human)
•* NOIHV-82915-01 Therapy for hypertension in the general
population (human)
DIAGNOSIS, DIAGNOSTIC TESTS*
SEE ALSO BILIARY TRACT DISORDERS DIAGNOSIS (INCL
EXAMS)*
SEE ALSO BLOOD AND RE DISORDERS DIAGNOSIS (INCL
E)(AMS)*
SEE ALSO BLOOD COAGUUTION TESTS*
SEE ALSO BLOOD (HEMATOLOGIC) TESTS*
SEE ALSO CARBOHYDRATE BAUNCE. GLUCOSE TOLERANCE
SEE ALSO CARDIOVASCULAR DISORDERS DIAGNOSIS*
SEE ALSO CEREBROVASCULAR DISORDERS DIAGNOSIS (INCL
EXAMS)*
SEE ALSO CHEMISTRY, CLINICAL
SEE ALSO COMMUNICABLE DISEASES DIAGNOSIS*
SEE ALSO DIAGNOSTIC QUALITY-STANDARDS, DIAGNOSTIC
PROCEDURES SAFETY
SEE ALSO ENDOCRINOLOGY. ENDOCRINE DISORDERS
DIAGNOSIS
SEE ALSO EYE DISORDERS DIAGNOSIS (INCL EXAMS)*
SEE ALSO GASTROINTESTINAL VISUALIZATION*
SEE ALSO GENETIC DISORDERS DIAGNOSIS*
SEE ALSO HEART DISORDERS DIAGNOSIS (INCL EXAMS)*
SEE ALSO HYPERSENSITIVITY TESTS
SEE ALSO IMMUNOLOGICAL TESTS AND IMMUNOASSAY.
IMMUNOLOGICAL TESTS*
SEE ALSO IMMUNOPATHOLOGY. DIAGNOSIS*
SEE ALSO KIDNEY DISORDERS DIAGNOSIS (INCL EXAMS)*
SEE ALSO KIDNEY VISUALIZATION*
SEE ALSO LIVER DISORDERS DIAGNOSIS (INCL EXAMS)*
SEE ALSO METABOLIC DISORDERS DIAGNOSIS*
SEE ALSO METABOLIC DISORDERS INBORN DIAGNOSIS*
SEE ALSO NEOPLASMS DIAGNOSIS
SEE ALSO NEOPUSMS RELATED INTEREST, SARCOIDOSIS,
KVEIM FACTOR
SEE ALSO NERVOUS DISORDERS DIAGNOSIS (INCL EXAMS)*
SEE ALSO NEUROMOTOR DISORDERS DIAGNOSIS (INCL
EXAMS)*
SEE ALSO NEUROPjrCHOLOGICAL TESTS*
SEE ALSO PSYCHOLOGICAL TESTS (GENERAL)*
SEE ALSO RADIOAUTOGRAPHY*
SEE ALSO RADIODIAGNOSIS AND RADIODIAGNOSTIC METHODS
SEE ALSO RADIOGRAPHY*
SEE ALSO RADIOISOTOPE (NUCLEAR) MEDICINE, STABLE
(LABELED) ISOTOPE DIAGNOSIS
SEE ALSO RESPIRATORY DISORDERS DIAGNOSIS*
SEE ALSO RESPIRATORY VISUALIZATION*
SEE ALSO SKELETAL DISORDERS DIAGNOSIS (INCL EXAMS)*
SEE ALSO THYROID FUNCTION
NOlHI-02216-10 To develop biological flow NMR concept
(human, mammals non human)
ROlHL-12711-09 Mathematical approach to cardiovascular
mechanics (human, animals)
ROlHL-13917-20 Secretion and effects of adrenal
hormones (human, rabbits, sheep)
ROlHL-16233-05 Molecular cardiology of MDP-induced left
ventricular failure (dogs)
** R01HL18561-03 Radioimmunoassay of angiotensinogen
(human)
ROlHL-20859-02 Beta adrenergic catecholamine receptor
NOlHV-53010-03 NAS-NRC twin registry
DIAGNOSTIC TESTS, BIOPSY*
SEE ALSO DIAGNOSTIC TESTS, CYTODIAGNOSIS*
ROlHL-02254-23 Blood coagulation and hemorrhagic
disease (human, animals)
ROlHL-04457-20 Cellular aspects of active transport (fish,
rabbits, anurans, turtles)
** POlHL-06312-17 0039 Surgical cardiology - Cardiac
transplantation-Biopsy correlates of rejection
P01HL06370-17 0013 Cardiopulmonary and renal
pathology research center - Morphologic analysis of
vascular prosthesis (human, dogs)
** POlHL-13108-09 0003 Clinical heart transplantation ■
Endomyocardial biopsy pathology
POlHL-17417-05 0003 Experimental lung transplantation
- Methods for detecting lung allograft rejection (dogs)
P50HL-17651-04 0036 Ischemic heart disease specialized
center of research Core facilities -Cardiovascular
pathology (human, dog)
(contd)
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
**0nented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
DIA
I7S
DIA
Regional lung function in man
Origins of attierosclerosis (human)
Genetic and environmental influences on
POIHL 1/813 04 0002 Lung disuse ind the oiyienition
of blood and lissut Diffuse inleistitid lung diseuMi
Ultiistiuctuial ibnoinKlilies ()ium<n)
** POIHI 18646 03 0009 Studies basic to liead
tiansplantation Pathologic aspects of caidiac allogiaft
leieclion (sheep, dogs)
DIAGNOSTIC TESTS, BIOPSY, MICROPUNCTURE'
PUIHI 0628b 18 019/ Caidiovasculai lespiiatory
physiology and biochemistry Miciopertusion and
miciopunctuie of renal tubules (hamsters, desert rats)
POIHL 0628b 18 0198 Caidiovascular respiratory
physiology and biochemistry Renal tubular secretion of
hydrogen ion (animals)
ROIHL 14133 08 Intrarenal regulation of sodium
reabsorption (dogs, hamsters, rats)
P50HL 141^9 08 0008 Specialised center of research in
hypertension Renal function and sodium metabolism in
hypertension (rats, human, rabbits)
DIAGNOSTIC TESTS, CYTODIAGNOSIS*
ROIHL I388S 08 0009 Cystic fibrosis and pulmonary
disease Respiratory mucus glycoproteins (human, rabbits)
ROIHL 1887803 Familial hypercholesteremia-Studies of
fibroblasts (human)
DIAGNOSTIC TESTS, CYTODIAGNOSIS,
CIUOINHIBITORY TEST*
P50HL 19157 02 0001 Studies in cystic fibrosis and
bronchiolitis Laboratory core unit
P50HL 19157 02 0007 Studies in cystic fibrosis and
bronchiolitis Analysis ot cystic fibrosis factors (human)
DIAGNOSTIC TESTS, EARLY DIAGNOSIS*
SEE ALSO PREGNANCY, ANTEPA:)TUM DIAGNOSIS
ROIHL 00487 29 Vasomotor tone and venous return
(human, dogs, monkeys )
POIHL'04664'18 0007 Cardiovascular and lung dynamics
Development and application of ultrasound imaging
techniques
** POlHL-07293-17 0054 Non-invasive cardiovascular
measurements - Detection of arterial occlusive disease
(human)
** ROIHL 10009- 13
ROlHL-10160-13
ROlHL-12833-09
lung disease (human)
** P01HL-13108-09 0014 Clinical heart transplantation -
Platelets and coagulation in accelerated graft coronary
atherosclerosis
P50HL-14141-05 0002 SCOR for atherosclerosis in
childhood - Intrauterine environment of proband group
(human)
ROlHL-14651-05 Mechanical behavior of left ventricle
(dogs, rats)
ROlHL-14692-06 Alpha 1 antitrypsin deficiency and
pulmonary disease (human)
P50HL-15103-07 0001 A/S SCOR -Early natural history of
arteriosclerosis - Clinical research -Bogalusa heart study
(children)
POlHL-15194-07 0024 Pathophysiology of
cardiopulmonary dysfunction - Distribution of ventilation -
Airflow limitation in COLD (human)
ROlHL-15528-05 Renin kinetics in hypertensive and
uremic plasma (human, dogs)
P60HL-1 5999-05 0004 Miami comprehensive sickle cell
center - Education, screening and counseling
P60HL- 17269-04 0007 National heart and blood vessel
research and demonstration center - Correlative studies of
experimental myocardial ischemia (dog)
ROlHL-17355-04 Pulmonary vascular adjustments in
circulatory collapse (dogs, rats)
POlHL-17417-05 0003 Experimental lung transplantation
- Methods for detecting lung allograft rejection (dogs)
ROlHL-17543-03 0001 Magnetic tracers for diagnosis of
lung disease - Chronic, interstitial lung disease (human,
rabbits)
P50HL18323-04 0035 SCOR hypertension center - Control
of high blood pressure at the work site
** POlHL-18576-03 0013 Thrombosis research program
project - Early warning and monitoring test systems in
thrombotic disease (human)
POlHL-18646-03 0002 Studies basic to heart
transplantation - Detection of rejection (dogs)
** POlHL-18646-03 0008 Studies basic to heart
transplantation - Immunophysiology and early detection of
rejection (dogs)
ROlHL-18873-02 Early radiologic diagnosis of cardiac
failure (monkey)
** P50HL-19156-02 0002 Pulmonary SCOR-Chronic diseases
of airways - Early detection of emphysema and chronic
airway obstruction (human, dog)
M POlHL-19717-02 Response of the lung to injury
POlHL-19717-02 0039 Response ot the lung to injury -
Lung scanning in alveolitis and asbestolic interstitial
pneumonia (human, animal)
POlHL-19717-02 0043 Response of the lung to injury -
Asbestosis as a model of usual interstitial pneumonia
(human)
** POlHL-19717-02 0044 Response of the lung to injury -
Lung sound analysis (human)
•* POlHL-19717-02 0045 Response of the lung to injury -
Ultrasound studies (human, hamsters)
ROIHI 198/0 03 Hypertensive progeny Physical and
humoral precursor search
ROIHI 19922 03 Childhood determinants of blood pratiure
ROIHL 19929 03 High blood pressure in the young.
prevalence and precursors (human)
ROIHL 19930 03
newborn twins
ROIHI 19962 03
A prospective study Blood pressure in
High blood pressure in young people in
Factors in blood pressure levels of
lecumseh
ROIHL 20005 03
children
ROIHL 20034 03 Hypertension Psychophysiologic and
genetic precursors (human)
ROIHL 20159 03 Genetic epidemiology of precursors of
hypertension (human)
Etiology ot myocardial infaction (human)
Detection of faniiiial hypercholesterolemia
Respiratory neurochemical control
Right ventricular contraction and
A routine screening analysis for
Behavorial approaches to adolescent
•• ROIHL 20645 01
ROIHL 2080/02
(human)
ROIHL 2084702
(human, goats)
•• R23HL21197 02
relaxation (dogs)
ROIHL 2148701 Molecular characterization of
Glanzmann's thrombasthenia (human)
*• P01HL21584 02 0006 Respiratory mechanics in normal
and abnormal states Respiratory mechanics in health and
disease (human, pigs)
R01HL21846-01 Cardiac failure detection by radiography
and optics (monkeys)
R23HL-21917-0I Adrenal steroids in adolescent and adult
hypertension
R01HL22298-02 Origins of hypertension (human)
** ROIHL 22723-01 The morphologic basis of airflow
obstruction (human)
ROIHL 22821-01
myoglobinemia
R18HL 22934-01
hypertension
ROlHL-22976-01 Nonuniform ventilation and diffusing
capacity (human)
ROlHL-23194-02 Genetics of hypertension and associated
variables (human)
DIAGNOSTIC TESTS, ENDOSCOPY*
SEE ALSO RESPIRATORY VISUALIZATION, BRONCHOSCOPY*
** ROlHL-13885-08 9003 Cystic fibrosis and pulmonary
disease Fiberoptic bronchoscopy core facility (human,
dogs, sheep)
** P60HL-23282-01 0001 Comprehensive hospital/community
sickle cell center - Fetoscopy for intrauterine diagnosis of
hemoglobinopathy (human, monkeys)
DIAGNOSTIC TESTS, NON-INVASIVE*
ROlHL-00487-29 Vasomotor tone and venous return
(human, dogs, monkeys )
ROlHL-0 14 86-23 Quantitative study of T-wave mechanisms
(human, rabbits, dogs, chickens)
ROlHL-04666-19 Artificially paced hearts -Technology,
physiology (human, dogs)
ROlHL-06222-18 Clinical and laboratory studies in lipid
metabolism (human, mammals, non-human)
POlHL-06285-18 0155 Cardiovascular-respiratory
physiology and biochemistry - Therapeutic alterations,
contractile state in heart failure
POlHL-06285-18 0156 Cardiovascular-respiratory
physiology and biochemistry - Myocardial performance
following revascularization (human)
POlHL-06285-18 0157 Cardiovascular-respiratory
physiology and biochemistry - Left ventricle outflow
impedance analysis (human)
POlHL-06296-18 0003 Cardiovascular and pulmonary
adaptation to stress - Human exercise studies (human,
dogs)
M POlHL-06308-18 Mechanisms and therapy of circulatory
disease
POlHL-06308-18 0010 Mechanisms and therapy of
circulatory disease - Ventricular arrhythmias during exercise
to CHD and myocardial ischemia (human)
POlHL-06308-18 0011 Mechanisms and therapy of
circulatory disease - Blood flow and electrical dysfunction
in ventricular arrhythmia (human)
POlHL-06308-18 0012 Mechanisms and therapy of
circulatory disease - Echocardiographic evaluation of
hemodynamics of arrhythmia (human)
POlHL-06308-18 0042 Mechanisms and therapy of
circulatory disease - Echocardiographic assessment of
arrhythmias-Myocardial tissue type (human, dogs)
POlHL-06308-18 0044 Mechanisms and therapy of
circulatory disease ■ Echocardiography to determine site of
ectopic impulse formation (human, dogs)
ROlHL-07139-17 Cardiodynamics and metabolism of
congestive failure (human, dogs)
M POlHL-07293-17 Non-invasive cardiovascular
measurements
POlHL-07293-17 0041 Non-invasive cardiovascular
measurements - Ventricular volumes and dimensions
(human)
POlHL-07293-17 0043 Non-invasive cardiovascular
measurements - ECHO-Doppler instrumentation for cardiac
measurements (human)
POlHL-0729317 0044 Non-invasive cardiovascular
measurements - Cardiac duplex scanner
POIHL 0/293 1/ 0045 Non invativt caidimatculai
ffleaiuremanli Cardiac scanner trantducti position
locating lystamt (human)
POIHt 0/291 1/ 004(j Non invativa i.aidiovasr.ular
measurements Caidiac scanner iignal piocet*.ort
POIHI 0/293 1/ 004/ Non invasive cardiovascular
measurements Cardiac scanner system software
POIHI 0/293 1/ 0048 Noninvasive cardiovascular
measurements Cardiac scanner recording and display
systems component
POIHL 0/293 1/ 0049 Non invasive cardiovascular
measurements Cardiac scanner enginMring evaluation
and error analysis
POIHL 0/293 1/ OOSO Non invasive cardiovascular
measurements Cardiac dimensions measurements
engineering evaluation and error analysis
POIHL 0/293 1/ 0051 Noninvasive cardiovascular
measurements Physiologic pj;''uation of duplex scanner
(dogs)
POIHL 0/293 1/ 00. . .ive caidio.a-.. ulai
measurements Clinical evaluation of the duplex scanner
(human)
P01HL07293 17 0053 Non invasive cardiovascular
measurements Clinical evaluation of cardiac dimensions
using the duplex scanner (human)
P0IHL07293 1/ 0054 Noninvasive cardiovascular
measurements Detection of arterial occlusive disease
(human)
P01HL07293 17 0055 Non invasive cardiovascular
measurements Peripheral vascular transducer position
locating system
POIHL 07293 17 0056 Non invasive cardiovascular
measurements Peripheral vascular system software
POIHL 07293 17 0057 Non invasive cardiovascular
measurements Peripheral vascular scanner engineering
evaluation and error analysis (human)
P01HLO7293-17 0058 Non-invasive cardiovascular
measurements Peripheral duplex scanner physiologic
evaluation
P01HL07293-17 0059 Non-invasive cardiovascular
measurements - Intracardiac blood flow measurement
(human)
POlHL-07895 15 0045 Environmental biomedical research
program - Extravascular lung water dynamics in pulmonary
oxygen toxicity (human, baboons)
ROlHL-09609-11 Lung volume and breathing mechanics
during anesthesia (human)
ROlHL-10009-13 Regional lung function in man
POlHL-10342-13 0008 The integrated function of
respiration and circulation Respiratory mechanics and the
circulation (human, dogs)
ROlHL-10417-12 Multiple systems in electrocardiography
(human)
R01HL-10622-12 Volumes and compliance of pulmonary
circulation (human, dogs)
POlHL-1 1310-12 0091 Mechanisms of cardiovascular
disease - Noninvasive techniques in cardiovascular
diagnosis (human)
POlHL-12373-10 Cardiopulmonary physiology and
pathophysiology
POlHL-12373-10 0002 Cardiopulmonary physiology and
pathophysiology Determinants of performance of the
whole heart (dogs)
POlHL-12373-10 0003 Cardiopulmonary physiology and
pathophysiology - Myocardial function in man
POlHL-12373-10 0005 Cardiopulmonary physiology and
pathophysiology Characterization of fetal and neonatal
myocardium (human, cats)
ROlHL-12715-10 Dynamic cardiovascular measurement
using ultrasound
POlHL-13108-09 0001 Clinical heart transplantation ■
Therapy and prognosis (human)
POlHL-13108-09 0017 Clinical heart transplantation -
Electrophysiology of the transplanted denervated human
heart
' POlHL-13108-09 0024 Clinical heart transplantation -
Response of denervated heart to stress-Noninvasive
(human)
POlHL-13738-08 0002 Cardiac assist devices and
artificial hearts - Total replacement with artificial heart
(calves, sheep, ponies)
POlHL-14388-07 0185 Regulation of the circulation in
pathological states ■ Reflex control of venous tone (human.
rabbits, dogs)
POlHL-14388-07 0208
pathological states
and hypertensive man
POlHL-14414-07 0008 Environmental influences on
cardiorespiratory and cellular functions - Energetics of
swimming (human)
POlHL-14580-07 0002 Program proiect in respiratory
mechanics - Airvtay aerodynamics (human, dogs)
ROlHL-1468805 Myocardial assessment by inverse
electrocardiography (monkey)
ROlHL-14785-07 Ultrasonic scattering for tissue
characterization (dogs, cattle, human)
' ROlHL-15016-07 New concepts in cardiac ultrasound
technology (human)
' P60HL-15158-07 0025 Comprehensive sickle cell center
Cardiovascular evaluation of children with sickle cell
disease (human)
(contd)
Regulation of the circulation in
Baroreceptor reflex function in normal
'Excludes HHJtine methodotogy OR covers only general projects which preclude indexing at the specific level.
*'0riented significantly to above subject.
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number
DIA
R01HL16076-06 Electrophysiology of fibrillation and
defibrillation (human)
ROlHL-16325-03 Breathing patterns in man
P01HL1638704 0005 The blood vessel and
thrombogenesis ■ Fluid engineering considerations in
thrombogenesis
R01HL1655305 Diagnosis of myocardial infarction by
radioisotopes (mice, rats, goats)
ROlHL-16784-03 Lung tissue and water volume (human,
dogs)
R01HL16830-05 Non-invasive determination of aortic
blood velocities (human)
ROlHL-16901-05 Multipolar linkage between heart
geometry and surface (human, dogs)
R01HL16908-04 Myocardial function, risk factors and
future CHD (men)
R01HL16909-04 Myocardial function, risk factors and
future CHD (men)
** P60HL-1726904 0027 National heart and blood vessel
research and demonstration center • Non-invasive
evaluation of cardiac function -Ischemic heart disease
(human, dog)
POlHL-17421-05 0007 Regulation and exchange in the
microcirculation Core facilities -Fluorometric measurement
methods for microcirculation
ROlHL-1 7513-04 Role of PF-4 in detecting and promoting
thrombosis (human, primates)
** ROlHL-1754303 0002 Magnetic tracers for diagnosis of
lung disease - Magnetite as an Index of asbestos exposure
(human)
** ROIHL 17543-03 0003 Magnetic tracers for diagnosis of
lung disease • Occupationally accumulated magnetite for
diagnosis of lung disease (human)
R01HL17578-04 Exercise performance in children with
heart disease
ROlHL-1760403 Wearable blood pressure and EGG
recording system
P50HL-17646-04 0009 Study of ischemic heart disease -
Regional metabolic derangements indicating ischemia
(rabbit, dog, human)
P50HL-17646-04 0010 Study of ischemic heart disease ■
Compliance in ischemic myocardium -Altered cardiac
performance (human, dogs)
P50HL-17648-04 0004 Study of ischemic heart disease -
Radionuclide imaging studies (human, pig)
P50HL-17651-04 0032 Ischemic heart disease specialized
center of research • Cardiovascular surgery core (human,
dogs)
** P50HL-17651-04 0048 Ischemic heart disease specialized
center of research • Non-invasive detection of ischemic
heart disease
P50HL-17655-04 0006 Study of ischemic heart disease ■
Evaluation of coronary artery bypass graft surgery (human)
P50HL-1 7655-04 0011 Study of ischemic heart disease -
Core facility-Cardiovascular nuclear medicine (human, dog)
P50HL-1767004 0014 Study of ischemic heart disease -
Real time ultrasound imaging in ischemic heart disease
(human, dog)
P50HL-17670-04 0015 Study of ischemic heart disease -
Radionuclide studies of myocardial ischemia (human)
P50HL-17670-04 0020 Study of ischemic heart disease -
Radionuclide evaluation of coronary artery disease (human,
dog)
P50HL-1 7682-04 0003 Study of ischemic heart disease -
Effects of myocardial revascularization in man
P50HL-1768204 0008 Study of ischemic heart disease -
Clinical core unit
P50HL-1 7682-04 0011 Study of ischemic heart disease -
Nuclear medicine core unit (human, dogs, rabbits, mice)
ROlHL-17826-04 Oxygen delivery to tissue (rat. dog)
ROlHL-17931-04 Normalized body surface potential maps
(children)
M ROlHL-17993-04
inserted markers
ROlHL-17993-04 0001 Ventricular dynamics from
surgically inserted markers - Effects of aortocoronary
bypass graft surgery on ventricular function (human)
ROlHL-17993-04 0002 Ventricular dynamics from
surgically inserted markers - Left ventricle function in
human cardiac allograft
ROlHL-17993-04 0005 Ventricular dynamics from
surgically inserted markers - Cardiac dimensions and
dynamic after mitral, aortic valve surgery (human)
ROlHL-18398-04 Mechanisms of delayed and asymetric
ventricular conduction (human, dogs)
ROlHL-18492-03 Measurement of regional coronary flow
reserve (human, dogs)
** POIHL- 18646-03 0008 Studies basic to heart
transplantation - Immunophysiology and early detection of
rejection (dogs)
** ROlHL-18710-02 Non-invasive reflection oximetry in
peripheral tissue (dogs)
ROlHL-18805-04 0005 Sudden cardiac death and the
onset of myocardial infarction - Sudden death survivors-
Radionuclide studies (human)
ROlHL-18873-02 Early radiologic diagnosis of cardiac
failure (monkey)
** ROlHL-18977-03 Non-invasive diagnosis of peripheral
arterial disease (human, dogs)
ROlHL-19019-03 Accurate transcutaneous Doppler blood
flow monitoring
Ventricular dynamics from surgically
176
ROlHL-19038-02 Plethysmographic evaluation of carotid
blood flow (human, rabbits, dogs)
ROIHL 1911803 Measurement of airways mechanics
(human, dog)
ROlHL-19135-04 Heterogeneity of regional myocardial
blood flow (dogs)
P50HL-19155-02 0002 Pathophysiology of pulmonary
edema - Non invasive measurement of protein turnover in
human lung (also sheep)
P50HL191 87-02 0009 Pediatric pulmonary SCOR -Hyaline
membrane disease - Non-invasive measurement and
monitoring of arterial oxygen tension (dogs, sheep)
P50HL-1919002 0009 Pulmonary SCOR -Pathophysiology,
management of IRDS - Developing non-invasive neonatal
pulmonary monitoring systems (rabbit, human)
ROlHL-19246-03 Regression of cardiac hypertrophy-
Myocardial and renal (human)
ROIHL 19341-03 Ultrasonic detection of the atherosclerotic
plaque
ROIHL- 193 52-03 Respiratory heat and water loss in
neonates
P50HL-1936202 0011 A/S SGOR -Atherosclerosis in
nonhuman primates Chronic hypertension induced by
operant conditioning techniques (baboon)
ROlHL-19391-03 Dynamic determinants of left ventricular
filling (dogs)
R01HL19406-03 Grading of atherosclerosis by CW doppler
ultrasound (human, dogs)
R01HL19425-03 Cardiac function in hypertrophy (dog)
ROlHL-19486-03 Dipole moment measurement of cardiac
mass (rabbits, pigs)
ROlHL-1953703 Detection of myocardial injury with
ultrasound (dogs)
POlHL-19717-02 0044 Response of the lung to injury -
Lung sound analysis (human)
POlHL-197 17-02 0045 Response of the lung to injury •
Ultrasound studies (human, hamsters)
ROlHL-19768-02 Recording and analysis of low levels
cardiac signals (human, dogs)
R01HL19973-01 Non-invasive sichled cell monitor
development (human)
ROlHL-201 10-02 Microwave methods of lung water
measurement (dogs, phantom models)
• ROlHL-20328-01 Noninvasive assessment of autonomic
cardiac control (dogs)
ROlHL-20347-02 Bolus-response measurement of lung
function (human)
ROlHL-2037302 Cardiovascular aging in young men and
women
ROlHL-20630-03 Development of a pulsed Doppler velocity
detector (human, animals)
ROlHL-208 15-02 Validation of indirect tests of small
airways function (human, dogs, ponies)
ROlHL-20898-02 Ultrasonic evaluation in direct arterial
surgery (models, cattle, human)
P50HL-2 1006-02 0005 Specialized center of research in
arteriosclerosis • Regional myocardial perfusion in patient
with coronary artery disease (also dogs)
R23HL-21168-01 Hypoxemic respiratory failure-Physiologic
evaluation (human, dogs)
ROlHL-21273-02 Fibrinogen labeling with radiometals
ROlHL-21278-01 Abnormal cardiac wall motion viewed
ultrasonically (human, dogs, phantoms)
ROlHL-21523-01 Hemodynamic effects of dietary sodium
in man
ROlHL-2 1684-02 0001 Radionuclide infarct sizing and
therapy evaluation • Evaluating preservation of ischemic
myocardium by radioisotope methods (dog)
ROlHL-2 16 84-02 0004 Radionuclide infarct sizing and
therapy evaluation - Image analysis-Kinetics of infarction,
ventricular function (human, animal)
ROlHL-2168402 0005 Radionuclide infarct sizing and
therapy evaluation - Clinical evaluation of radioisotope
imaging methods for quantifying infarct size
ROlHL-21690-02 Sequential multinuclide study of acute
infarction (human, dogs)
ROlHL-21697-01 Myocardium infarct sizing by 82Rb
emission tomography (dogs, human)
ROlHL-217 10-01 Electrocardiographic methods of
quantifying infarct size (human, dogs)
ROlHL-217 19-01 Computed cardiac tomography in infarct
sizing (dogs, human)
ROlHL-21793-02 Functional infarct size by gated
radioangiography (human, dogs)
ROlHL-21846-01 Cardiac failure detection by radiography
and optics (monkeys)
R23HL-22004-01 Imaging and EGG studies in acute and
chronic IHD (human)
ROlHL-22080-01 Phosphorus NMR studies on cardiac
tissue (rats, rabbits)
ROlHL-22255-01 The etiology/prevalence of peripheral
arterial disease (human)
ROlHL-22296-01 Autonomic mechanisms in man
'* ROlHL-22321-01 Cardiac output from the
pneumocardiogram (dogs)
DIA
ROlHL-22604-01
studies (human)
ROlHL-22750-01
rhythm (human)
R23HL-22787-01
Non-invasive system for arteriosclerosis
Digoxin in heart failure with sinus
ROlHL-2232601
output (dogs)
ROlHL-22506-01
hypertensions
ROlHL-22547-01
disease (human)
Noninvasive measurement of cardiac
Hemodynamics of the clinical
Behavioral treatment of Raynaud's
Cardiac volume by biplane
echocardiography (human)
ROlHL-22809-01 Coronary-prone behavior and
cardiovascular reactivity (human)
ROlHL-22844-01 Phrenic nerve pacing-Noninvaslve
diaphragm analysis (human, dogs)
" ROlHL-22852-01 Diagnostic techniques in venous
thromboembolism (human)
** ROlHL-22854-01 Non-invasive blood pressure
measurement (rats)
R18HL-22934-01 Behavorial approaches to adolescent
hypertension
ROlHL-22982-01 Multicenter postcoronary risk
stratification program (human)
ROlHL-2320101 Mechanisms of hypertension (human,
rats)
NOlHR-62920-02 Noninvasive diagnosis of pulmonary
hypertension (dog. human)
NOlHV-52966-01 Development and evaluation of an
ultrasonic imaging system (swine)
** NOlHV-72924-04 Non-invasive detection of atherosclerotic
lesions (human, animals)
** NOlHV-72925-04 Non-invasive detection of atherosclerotic
lesions (human, monkeys, dogs)
NOlHV-72926-04 Ultrasonic imaging development
NOlHV-72927-00 Systems for non-invasive detection of
atherosclerotic lesions (human)
NOlHV-72929-01 Improved detection of atherosclerosis
(human, dogs)
** NOlHV-72931-02 Non-invasive detection of atherosclerotic
lesions (human, dogs)
** NOlHV-72932-00 Non-invasive detection of atherosclerotic
lesions (human, phantoms)
DIAGNOSTIC TESTS, RAPID DIAGNOSIS*
ROlHL-0777615 Sudden death and cardiac arrhythmias
(human, dogs, cats)
" P01HL13108-09 0012 Clinical heart transplantation -
Human T cell sheep erythrocyte receptors
POlHL-15194-07 0025 Pathophysiology of
cardiopulmonary dysfunction - Myoglobinemia as an index
of myocardial ischemia and infarction
POlHL-17417-05 0003 Experimental lung transplantation
- Methods for detecting lung allograft rejection (dogs)
ROlHL-18776-04 Prevention of acute and fatal
cardiovascular disease (human)
** ROIHL- 19083-02 Rapid specific micro measurement of
blood cholesterol
** ROlHL-20751-01 High speed liquid chromatography of
hemoglobins (human)
DIALYSIS (BLOOD)
SEE BLOOD TREATMENT, HEMODIALYSIS
DIAMINE OXIDASE
SEE OXIDOREDUCTASES, AMINE OXIDASE (PYRIDOXAL-
CONTAINING)
DIAAAINES
SEE AMINES. DIAMINES
DIAMINO ACIDS, ARGININE
P50HL-14237-07 0001 Support for arteriosclerosis center
- Role of apolipoproteins in lipoprotein catabolism (human,
rats)
ROlHL-14313-07 Apoproteins of triglyceride rich
lipoproteins (human, squirrel monkeys, rats)
POlHL-22633-01 0004 Cellular and molecular biology of
lipoprotein metabolism - Lipid-lipid and lipid-protein
interactions in serum lipoproteins (human, rats)
DIAMINO ACIDS, LYSINE
** ROlHL-11614-11 Trace elements in nutrition (chickens.
rats, human)
ROlHL-13909-27 Physiochemistry and Immunology of
macromolecules
POlHL-15195-04 0001 Program project in biological
materials - Design and synthesis
ROlHL-18819-07 Chemical studies on sickle cell
hemoglobin (human)
R01HL19633-02 Pathogenesis and pharmacology of lung
fibrosis (rats, rabbits)
POlHL-19717-02 0001 Response of the lung to injury -
Lung elastic tissue (animals)
POlHL-19717-02 0004 Response of the lung to injury -
Regulatory and physical-chemical properties of lung lysyl
oxidase (animals)
ROlHL-20074-02 Structure and function of amidinated
human hemoglobin
DIAMINO ACIDS, LYSINE, HYDROXYLYSINE
ROlHL-18593-03 Characterization of heart valve collagen
(human, pig)
DIAMOX
SEE SULFONAMIDES, AGETAZOLAMIDE
DIAPHRAGM
SEE BODY CAVITIES. DIAPHRAGM
(contd)
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level
**0rieflted significantly to above subject.
M Grant has subprojeds describing specific research aspects.
See Appendix for investigator's name and grant number
DIA
177
OIAPHRAOMATIC HERNIA
Sll BODY CAVIIY DISORIURS. DIAPHRAGMATIC HERNIA
DIASTOLIC AUGMENTATION
Si I CARDIOVASClllAR SURCfRY, CIRCULAtORY ASSIST.
OIASIOUC AUCMINIAIION
DIAZEPAM
Stf A/fPIN£S. DIAZEPAM
DIAZEPINES
Sit AA PINES. DIAZEPINES
DIAZINODIAZINES, DIPYRIDAMOLE
POIHL 07293 W OOSg Noninvasive cardiovascular
measurements Peripheral duplex scanner physiologic
evaluation
** PO1HL07896 IS 0057 Environmental biomedical research
proiram Ellects ol dipyridamole and aspirin on
decompression thrombocytopenia (human)
ROIHL 10384 13 Blood flow and nucleotide metabolism
(animals)
ROIHI 13466 08 Pulmonary platelets in shock, trauma
and emboliiation (dogs. pigs, rats)
POIHI 13738 08 0003 Cardiac assist devices and
artificial hearts Pathophysiological effects of the artificial
heart (calves)
P50HL 14217 08 00S4 Specialized center of research in
thrombosis Coagulation section-Platelet aggregation
(human, pig. rabbit, dog)
ROIHL 1629205 0010 Surgery and nonobstructive
coronary insufficiency Effects of exercise on flow
distribution (dogs)
ROIHL 16412 04 Release of nucleosides from the ischemic
heart (human, dogs)
ROIHL 16437 05 Drug treatment of atherosclerosis
(rabbits, monkeys)
P01HL1857603 0001 Thrombosis research program
prDJect - Platelet damage from physical forces and
artificial surfaces (human)
P01HL18576-03 0007 Thrombosis research program
protect - Relationships between coagulability and
thrombosis (human, animals)
POlHL-18645-03 0006 Biology of the artery wall and
atherosclerosis - The platelet and atherosclerosis (monkeys,
baboons)
ROIHL 18932-03 Brain microcirculation observed in vivo
after trauma (mice)
R01HL1900103 Atherosclerosis in bleeder and drug
treated subjects (pigs)
R01HL1920203 Adenosine, prostaglandins in relation to
coronary flow (guinea pigs)
POlHL-19242-02 0003 Study of vascular smooth muscle -
Vasoactive metabolites from vascular muscle and
parenchymal tissue (animal)
RDlHL-19451-03 0004 Functional characteristics of the
left heart ■ Quantitative coronary arteriography (human)
ROlHL-19937-02 Vasodilators in experimental myocardial
infarction (dogs)
ROlHL-20337-02
ROlHL-21533-02
(human)
ROlHL-22005-01
myocardium (dogs)
P01HL-22163-D1 0003 Surface thrombogenesis-
Mechanisms and prevention - In vivo mechanisms of
biomaterial thrombogenesis and its prevention (baboons)
ROlHL-22445-01 Platelet inhibitors-Effect on coronary
bypass grafts (dogs)
DIAZOIODIAZINES, PYRAZOLOPYRIMIDINES
POlHL-20948-02 0003 Molecular basis of cholesterol
metabolism - LDL pathway in vivo (human, rats, guinea
pigs)
DIAZOLODIAZINES, PYRAZOLOPYRIMIDINES,
AUOPURINOL
ROlHL-20352-02 Defenses of lung cells against oxygen
toxicity (human, animals)
DIAZOXIDE
SEE THIAOIAZINES. DIAZOXIDE
DIBENAMINE (HYDROCHLORIDE)
SEE PHENYLALKYUMINES. BENZYUMINES. DIBENAMINE
DIBENZANTHRENES
SEE CYCLICS. CARBOPOLYCYCLICS. BENZANTHRACENES
DIBENZYLINE
SEE PHENYLALKYUMINES, BENZYLAMINES.
PHENOXYBENZAMINE
DICARBOXYLIC ACIDS, MALIC ACID
SEE ALSO OXIDOREDUCTASES. MALATE DEHYDROGENASE
P50HL- 17667-04 0012 Study of ischemic heart disease -
Biochemistry of normal and ischemic heart -Glycolysis (rats)
DICARBOXYLIC ACIDS, OXALACETATE
POlHL-16251-06 0002 Membrane-bound enzymes in heart
and other tissues - Structural basis of regulation of
cardiac succinate dehydrogenase
DICARBOXYLIC ACIDS, SUCCINIC ACID
SEE ALSO OXIDOREDUCTASES. SUCCINATE:(ACCEPTOR)
OXIDOREDUCTASE
Thromboembolic diseases (human)
Platelet inhibitor drug in coronary surgery
Intermittent retroperfusion of ischemic
ROIHL 21381 07 Ammo acid nrntabolivm in normd and
hypoxic myocardium (rabbits)
ROIHI 73128 01 Cardial rontiaclilily Kchemia and
hypoxiii (i.ihbils, i.ilsl
DICARBOXYLIC ALDEHYDES, MAIONALDEHYDE
ROIHL 18163 04 Red call membrtne alfecti du« to
oxidiiing agents
DICARBOXYLIC AMINO ACIDS, ASPARAOINE
ROIHL 18818 04 Sleieochemical mechanism ol sickling of
hemoglobin S (human)
DICARBOXYLIC AMINO ACIDS, ASPARTIC ACID
P50HL 17651 04 0041 Ischemic heart disease specialized
center of research Biochemical indices ol ischemic iniury
(guinea pig)
P50HL 17667 04 0012 Study of ischemic heart disease
Biochemistry of normal and ischemic heart Glycolysis (rals)
DICARBOXYLIC AMINO ACIDS, GLUTAMATES
SEE ALSO FOLIC ACID
SEE ALSO PEPTIDES. GLUTATHIONE
POIHL 11414 11 0033 Thrombosis and atherosclerosis
program Human coumarin induced prothrombin
POIHL 11414 11 0035 Thrombosis and atherosclerosis
program Mechanism of action of vitamin K (rats)
POIHL 1519504 0001 Program project in biological
materials Design and synthesis
ROIHL 15728-06 The carbohydrate of the blood-clotting
glycoproteins (mammals)
POIHL 16878 05 0004 Control of ventilation in health
and disease Neurotransmitters in the respiratory system
(cats)
P50HL-17651 04 0041 Ischemic heart disease specialized
center of research Biochemical indices of ischemic injury
(guinea pig)
** ROlHL-20161 02 Role of gamma-carboxyglutamic acid in
blood coagulation (human, cattle)
ROlHL-20577-03 The mechanism of action of vitamin K
ROIHL 20764-02 Elastin and calcification in pulmonary
and vascular disease (human, mammals)
ROIHL'2110502 Organ specific drugs -Cardiovascular and
renal effects (dogs)
ROlHL-21543-02 Structure-function relation of blood
clotting proteins (rabbits)
DICARBOXYLIC AMINO ACIDS, GLUTAMINE
POIHL- 151 95-04 0001 Program project in biological
materials - Design and synthesis
P50HL-17651-04 0041 Ischemic heart disease specialized
center of research Biochemical indices of ischemic injury
(guinea pig)
ROlHL-18818-04 Stereochemical mechanism of sickling of
hemoglobin S (human)
DICHLOROACETATE
SEE HALO FATTY ACIDS. CHLORO FATTY ACIDS.
DICHLOROACETATE
2,3-DICHLOROAMYLENEPHENOXYACETIC ACID
SEE PHENOXYACETIC ACIDS. 2,3-DICHLORO-4-(2-
METHYLBUTYDPHENOXYACETIC ACID
DICHLORO ETHYLENE
SEE HALOOLEFINS. VINYLEOENE CHLORIDE
2,3-DICHLORO-4-(2-
METHYLBUTYL)PHENOXY ACETIC ACID
SEE PHENOXYACETIC ACIDS. 2.3-DICHLORO-4-(2-
METHYLBUTYDPHENOXYACETIC ACID
DICHROISM, CIRCULAR
SEE OPTICS. DICHROISM CIRCULAR*
DICHROISM, CIRCULAR MAGNETIC
SEE OPTICS. DICRHOISM CIRCULAR MAGNETIC*
DICHROMOGRAPHY (X-RAY SPECTROMETRY)
SEE CHEMISTRY, ANALYTICAL METHODS. SPECTROMETRY, X-
RAY*
DIELECTRIC CHARGES IN TRANSPORT
ENERGETICS
SEE BIOLOGICAL TRANSPORT. TRANSPORT ENERGETICS
DIELECTRIC PROPERTIES
SEE ELECTRICITY-MAGNETISM. DIELECTRIC PROPERTIES
DIELS-ALOER REACTION
SEE CYCLIZATION. OIELS-ALDER REACTION
DIENCEPHALON-PITUITARY SYSTEM
(HORMONES)
SEE PITUITARY-OIENCEPHALON (HORMONES)
DIET
SEE NUTRITION. DIET
DIET PATHOGENIC
SEE NUTRITION. DIET PATHOGENIC
DIET SCHEDULE AND ROUTE
SEE NUTRITION. DIET SCHEDULE AND ROUTE
DIET THERAPEUTIC
SEE NUTRITION. DIET THERAPEUTIC
DIETARY AMINO ACID
Ml NIIIHIIIliN nil lAHY CONSrirUtNTS. DiriARY AMINO
Al.lll',
DIETARY CARBOHYDRATES
Sll NIIIMIIKJN iJlllAKir (.(INMIIIIINIS. UK lAHY
CARBOMYDRAIC,
DIETARY CONSTITUENTS
SEE NIJIRIMUN. UIITARY CONSTIIUCNTS (GENERAL)
SEE NUIRItKjN, DIITETICS
DIETARY DEFICIENCY
SET NUTRIIIONAI ABNORMAIITIES, MALNUTRITION (GENERAL)
DIETARY HABITS AND HYPERTENSION
SEE CARDIOVASCUIAR DISORDERS, HYPtRffNSION
(SYSTEMIC), ENVIRONMENT ASSOCIATED
DIETARY IRON
SEE NUTRITION. DIETARY CONSTITUENTS, DIFTARY IRON
DIETARY UPIDS
SEE NUTRITION, DIETARY CONSTITUENTS, DIETARY LIPIDS
DIETARY METALS
SEE NUTRITION, DIFTARY CONSTITUENTS, DIETARY TRACE
ELEMENTS AND MINERALS
DIETARY MINERALS
SEE NUTRITION, DIETARY CONSTTTUENTS, DIETARY TRACE
ELEMENTS AND MINERALS
DIETARY NUTRIENTS, GASTROINTESTINAL
ABSORPTION
SEE GASTROINTESTINAL FUNCTION, ABSORPTION TRANSPORT,
DIETARY NUTRIENTS
DIETARY PROTEINS
SEE NUTRITION, DIETARY CONSTITUENTS, DIETARY PROTEINS
DIETARY REQUIREMENTS
SEE NUTRITIONAL REOUIREMENTS
DIETARY RESIDUES-FIBERS
SEE NUTRITION, DIETARY CONSTITUENTS, DIETARY RESIDUES-
FIBERS
DIETARY SALTS
SEE NUTRITION, DIETARY CONSTITUENTS, DIETARY SALTS
DIETARY SUGARS
SEE NUTRITION, DIETARY CONSTITUENTS. DIETARY
CARBOHYDRATES
DIETARY SUPPLEMENTS
SEE NUTRfTIONAL REQUIREMENTS. DIETARY SUPPLEMENTS
DIETARY TRACE ELEMENTS AND MINERALS
SEE NUTRFTION. DIETARY CONSTITUENTS. DIETARY TRACE
ELEMENTS AND MINERALS
DIETETICS
SEE NUTRITION. DIETETICS
DIETHYLSTILBESTROL
SEE STILBENES. DIETHYLSTILBESTROL
DIFFERENTIATION
SEE CELL DIFFERENTIATION
SEE GROWTH AND DEVELOPMENT. HISTOGENESIS
DIFFUSION
SEE BIOLOGICAL TRANSPORT. PASSIVE TRANSPORT,
DIFFUSION
SEE PHYSICAL PROPERTIES. DIFFUSION
DIFFUSION HORMONES
SEE NEUROTRANSMITTERS (GENERAL)
DIGESTION
SEE GASTROINTESTINAL FUNCTION. DIGESTION
DIGESTIVE SYSTEM
SEE GASTROINTESTINAL SYSTEM (GENERAL)
DIGITALIS
SEE CARDIAC GLYCOSIDES, DIGITALIS
DIGITOXIGENIN
SEE CARDIAC GLYCOSIDES AGLYCONES, DIGITOXIGENIN
DIGITOXIN
SEE CARDIAC GLYCOSIDES, DIGITOXIN
DIGLYCERIDE PHOSPHOKINASE
SEE PHOSPHOTRANSFERASES, ATP:DIGLYCERIDE
PHOSPHOTRANSFERASE
DIGLYCERIDES
SEE LIPIDS, GLYCERIDES, DIGLYCERIDES
DIGOXIGENIN
SEE CARDIAC GLYCOSIDES AGLYCONES, DIGOXIGENIN
DIGOXIN
SEE CARDIAC GLYCOSIDES, DIGOXIN
DIGu'gLIELMO SYNDROME
SEE NEOPUSMS OF BLOOD AND RE SYSTEM, LEUKEMIA,
ERYTHROLEUKEMIA
(contd)
*Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
**Onented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
3A,
DIHYDROCHOLESTEROL
SEE CHOLESTANE SERIES, CHOLESTANOL
3A,7A-DIHYDROXY-5B-CHOLANIC ACID
SEE CHOUNATE SERIES, CHENODEOXYCHOUC ACID
OIHYDROXYPHENYLALANINE
SEE CYCLIC AMINO ACIDS, DOPA
3,4-DIHYDROXYPHENYLETHYLAMINE
SEE PHENYLALKYLAMINES, CATECHOUMINES, DOPAMINE
DIISOPROPYL FLUOROPHOSPHATE
SEE PHOSPHATES, FLUOROPHOSPHATES, OFP
DILANTIN
SEE IMIDAZOLEOIONES, HYDANTOINS, OIPHENYLHYDANTOIN
DIMERS
SEE MOLECULAR CONDENSATIONS, DIMERS
6,9-DIMETHOXY- 1 -VERATRYLISOQUINOLINE
SEE QUINOLINES, ISOQUINOLINES, PAPAVERINE
DIMETHYL-3'-AMINO-3'-DEOXYADENOSINE
SEE PURINE NUCLEOSIDES, ADENINE NUCLEOSIDES,
DiMETHYL-3'AMINO-3'-DEOXYA0EN0SINE
DIMETHYLBENZANTHRACENES
SEE CYCLICS, CARBOPOLYCYCLICS, BENZANTHRACENES
5,6-DIMETHYLBENZIMIDAZOLYL
CYANOCOBAMIDE
SEE VITAMIN 812
DIMETHYLSULFOXIDE
SEE SULFOXIDES, DIMETHYL SULFOXIDE
1 ,3-DIMETHYLXANTHINE
SEE PURINES. XANTHINES, THEOPHYLLINE
DIMORPHISM; POLYMORPHISM (BIOLOGY)
SEE BIOLOGY, POLYMORPHISM
DIMORPHOBIOTISM
SEE BIOLOGY, LIFE CYCLE
2,4-DINITROPHENOL
SEE NITROPHENOLS, 2,4 DINITROPHENOL
DIOLS
SEE ALCOHOLS, DIOLS
DIPEPTIDASES
SEE PROTEASES AND PEPTIDASES, DIPEPTIDASES
DIPHENHYDRAMINE
SEE PHENYULKOXYALKYLAMINES, DIPHENHYDRAMINE
O-DIPHENOL OXIDASE
SEE OXYGENASES, MONOPHENOL M0N00XY6ENASE
P-DIPHENOL OXIDASE
SEE OXYGENASES, MONOPHENOL MONOOXYGENASE
DIPHENYLHYDANTOIN
SEE IMIDAZOLEOIONES, HYDANTOINS, DIPHENYLHYDANTOIN
DIPHOSPHOGLYCERATES
SEE TRIOSE ACIDS, GLYCERIC ACID DIPHOSPHATES
DIPHOSPHONATES
SEE PHOSPHONATES, DIPHOSPHONATES
DIPHOSPHOPYRIDINE NUCLEOTIDE (REDUCED)
SEE PYRIDINE NUCLEOTIDES, NICOTINAMIDE RIBOTIOES,
NAD(H2)
DIPHTHERIA TOXIN
SEE IMMUNOLOGY, ANTIGENS BACTERIAL, DIPHTHERIA TOXIN
DIPLOCOCCUS PNEUMONIAE
SEE BACTERIA, STREPTOCOCCACEAE, STREPTOCOCCUS
PNEUMONIAE*
DIPOLE MOMENTS
SEE ELECTRICITY-MAGNETISM, DIPOLE MOMENTS
DIPYRIDAMOLE
SEE DIAZINODIAZINES, DIPYRIDAMOLE
DiSABUNG DISEASES
SEE DISEASES, DISABLING
DISACCHARIDE (OUGOSACCHARIDE)
INTOLERANCE
SEE METABOLIC DISORDERS INBORN, DISACCHARIDE
(OLIGOSACCHARIDE) INTOLERANCE
DISACCHARIDES, SUCROSE
P50HL19153-02 0005 SCOR-Pulmonary edemas-Eitology,
pathogenesis ■ Lung vascular permeability measured by
indicator dilution methods (sheep)
DISCRIMINATION
SEE SENSORY-PERCEPTUAL PROCESSES, DISCRIMInAiON
DISEASE CLASSIFICATION
SEE ALSO NEOPLASMS CUSSIFICATION AND STAGING
178
POlHL-04664-18 0011 Cardiovascular and lung dynamics
- Detection of abnormal segments of the human ventricle
by measure of asynergy
P01HL-04ee4-18 0012 Cardiovascular and lung dynamics
- Quantitative single plane left ventricular angiography
(human)
ROlHL-10582-12 Thrombosis and hemostasis-Analysis,
methods and standards (human, cattle, venom)
** P50HL-142 14-07 0033 Newborn lung center for hyaline
membrane disease - Statistical modeling, predictive
classification in clinical management of HMO
P60HL-15996-06 0005 Cincinnati comprehensive sickle
cell center - Factors precipitating crises (human)
P60HL 16008-06 0009 Wayne State University
comprehensive sickle cell center - Natural history of sickle
cell anemia (human)
** P60HL-17269-04 0004 National heart and blood vessel
research and demonstration center - Atherosclerosis-
Clinical surgical aspects (human)
P50HL- 176 48-04 0016 Study of ischemic heart disease -
Intraventricular conduction -Effect of pacing on conduction
and automaticity
P50HL-17667-04 0029 Study of ischemic heart disease -
Computer diagnosis of cardiac arrhythmias after open
heart surgery (human)
" P50HL- 176 70-04 0012 Study of ischemic heart disease -
Epidemiology of sudden death (human)
** P50HL- 183 18-03 0001 Pathogenesis and complications of
hypertension - Core clinical program
** P50HL-18323-04 0011 SCOR hypertension center -
Endocrine profiling on a selected normal population
(human)
** P50HL-18323-04 0043 SCOR hypertension center -
Pharmacology-Renin-aldosterone mechanisms in essential
hypertension (human)
** P50HL- 183 23-04 0044 SCOR hypertension center -
Angiotensin blockade to identify angiotensin II factor in
hypertension (human)
R01HL-18687-03 Pathophysiology of genetic
hypertriglycerinemias (human)
R01HL-18730-03 Role of mineralocorticoids in low renin
hypertension (human, rats)
ROlHL-18794-04 Prospective studies of conduction disease
(human)
ROlHL-18800-04 Prospective study of resuscitated sudden
death victims (human)
ROlHL-18805-04 0003 Sudden cardiac death and the
onset of myocardial infarction - Prediction from clinical and
laboratory assessments (human)
ROlHL-18808-04 0001 Prediction and prevention of
sudden cardiac death - Prognostic significance of
premature ventricular contractions (human)
ROlHL-18878-03 Familial hypercholesteremia-Studies of
fibroblasts (human)
POlHL-19717-02 0038 Response of the lung to injury -
Interstitial lung disease-Clinical, pathologic and
epidemiologic
POlHL-20948-02 0004 Molecular basis of cholesterol
metabolism - Genetic analysis of the LDL pathway (human)
** ROlHL-22963-01 Symbolic logic analysis of congenital
heart disease (human)
DISEASE CONTROL AND EPIDEMIOLOGY STUDY
SECTION
SEE EPIDEMIOLOGY AND DISEASE CONTROL STUDY SECTION
DISEASE CONTROL, COMMUNICABLE
(INFECTIOUS) DISEASES
SEE COMMUNICABLE DISEASE CONTROL
DISEASE PREVENTION, TOXICOLOGY RELATED
SEE TOXICOLOGY, POISON CONTROL AND PREVENTION
DISEASE PREVENTION AND CONTROL
SEE HEALTH, DISEASE PREVENTION AND CONTROL
DISEASE PRONENESS-RISK
SEE ALSO POPULATION STUDIES HUMAN, EPIDEMIOLOGY
** R01HL-01803-23 0020 Arteriosclerosis, glomenilonephritis,
rheumatic fever - Virus-induced arterosclerosis (chickens)
ROlHL-01979-22 Arteriosclerosis in zoo animals on
controlled diets (animals)
" POlHL-03174-23 0010 Mechanisms of acute vascular
reaction to injury - Search for mutagens in the human
blood (bacteria, animals)
** POlHL-03174-23 0013 Mechanisms of acute vascular
reaction to injury - Surface morphology of the aorta in
normal and injured states (rats, rabbits)
ROlHL-03429-18 Central nervous system and coronary
heart disease (human)
ROlHL-05806-18 Analysis of antiarrhythmic agents (dogs,
rabbits)
POlHL-06308-18 0010 Mechanisms and therapy of
circulatory disease - Ventricular arrhythmias during exercise
to CHD and myocardial ischemia (human)
POlHL-063 14-17 0059 Immunologic mechanisms in
cardiovascular disease - Immunogenetic response to
streptococcal antigens in man
ROlHL-07776-15 Sudden death and cardiac arrhythmias
(human, dogs, cats)
POlHL-08974-14 0005 Natural and experimental
atherosclerosis - Atherosclerosis, coronary heart disease
and sudden death (human)
DIS
POlHL-08974-14 0028 Natural and experimental
atherosclerosis - Geographic pathology of atherosclerosis
and coronary heart disease (human)
POlHL-09011-15 0018 A research and resource program
in blood - Hepatitis B in normal populations-Epidemiology,
risk factors and transmission
POlHL-09011-15 0023 A research and resource program
in blood - Evaluation of hepatitis B vaccine in endemic
settings (human)
POlHL-11310-12 0069 Mechanisms of cardiovascular
disease - Factors affecting mortality and morbidity after
heart surgery (human)
POlHL-11310-12 0070 Mechanisms of cardiovascular
disease - Factors affecting long-term mortality and
morbidity after heart surgery (human)
POlHL-12738-10 0117 Physiologic pharmacology and its
clinical applications - Ventricular arrhythmias in ischemic
heart disease (human)
ROlHL-12833-09 Genetic and environmental Influences on
lung disease (human)
ROlHL-13754-08 Postoperative thromboembolism in
surgical patients (human)
P50HL-14 136-07 0009 Pulmonary SCOR-Airways
obstructive diseases - Tuscon epidemiological study of
airways obstructive disease (human)
P50HL-14136-07 0017 Pulmonary SCOR-Airways
obstructive diseases - Pediatric airways obstructive disease
(human)
P50HL-14153-07 0001 Johns Hopkins Lung Center-
Chronic diseases of airways - Genetic and environmental
factors in chronic pulmonary disease (human)
' P50HL-14153-07 0010 Johns Hopkins Lung Center-
Chronic diseases of airways Risk factors for airways
obstruction in a rural community (human)
P50HL- 14 159-08 0021 Specialized center of research in
hypertension - Genetic studies of the physiology of
hypertension (human, rats)
' P50HL-14164-07 0041 A/S SCOR-Comparative and
experimental atherosclerosis - Nonhuman primate pediatric
atherosclerosis risk factor
P50HL-14ie4-07 0044 A/S SCOR-Comparative and
experimental atherosclerosis - Cell biology-atherosclerosis
project (pigeons)
P50HL-14218-07 0012 Pulmonary SCOR-Newborn lung
center - Longitudinal study of RDS-On-line fetal and
neonatal monitoring (human)
P50HL-14218-07 0015 Pulmonary SCOR-Newborn lung
center - Long term follow-up of infants surviving RDS-
Neurological outcome (human)
' P50HL-14230-07 0088 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Coronary risk factors in school children-
The Muscatine study
R01HL-14700-05 Humoral and lung protease-antiprotease
role In obstructive disease (human)
ROlHL-15047-06 Digital computer analysis of the
electrocardiogram (human)
P50HL-15092-07 0011 Immune and fibrotic response to
occupational environments - Respiratory and immunologic
responses in coffee plant workers
P50HL-15103-07 A/S SCOR-Early natural history of
arteriosclerosis
* P50HL-15103-07 0001 A/S SCOR-Early natural history of
arteriosclerosis - Clinical research-Bogalusa heart study
(children)
P50HL-15103-07 0013 A/S SCOR-Early natural history of
arteriosclerosis - Experimental models of atherosclerosis
(monkeys)
* P60HL-15162-07 0007 Comprehensive sickle cell center -
Core program-Demographic studies (human)
P60HL 15169-06 0009 Support for center for sickle cell
disease - Infections in sickle cell anemia (human)
ROlHL-151 74-06 CV disease epidemiology-Second
generation studies (human)
Follow-up study of acute coronary heart
Chemical-structural predispositions to
R01HL-15790-06
attacks (human)
POlHL-15832-06
lung Injury
ROlHL-16219-05 Mechanisms of atherogenesis in chronic
uremia (human, rats)
R01HL-16908-04 Myocardial function, risk factors and
future CHD (men)
ROIHL- 16909-04 Myocardial function, risk factors and
future CHD (men)
ROIHL- 17408-03 Fresh blood rheology-Relation to
cardiovascular risk (human)
ROlHL-17465-04 Beta-thalassemia screening and genetic
counseling
ROlHL-17516-04 Role of androgen as a risk factor in
atherogenesis (human, animals)
ROlHL-17580-04 The impact of stress on coronary heart
disease (men)
P50HL-17667-04 0001 Study of ischemic heart disease -
Natural history of ischemic heart disease (human)
P50HL17670-04 0012 Study of ischemic heart disease -
Epidemiology of sudden death (human)
ROlHL-17754-03 Pathogenesis and prevention of
hypertension sequelae (rats)
ROlHL-18235-03 Cardiovascular fitness and other risk
factors (human)
P50HL-18318-03 0012 Pathogenesis and complications of
hypertension - Behavioral factors in hypertension (human)
(contd)
Ixchides routine methodotogy OR covers only general projects which preclude Indexing at the specific level.
•• Jrcr<tf<1 vqnificantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
OIS
PbOHL 1831803 0018 Pitho|an«ls and compllcitioni ot
hyp«rtinsH)n Pltsm* ranin activity In chronic Ischemic
hurt diuax (human)
" PSOHL 18323 04 001? SCOR hyparlenslon ctnter Renin
as a iisk (actor (human)
PbOHl 18323 04 0035 SCOR hypertension center Control
ot hi|h blood prassure at the work site
ROIHl 184b6 03 Cardiovascular lollow up ot hypertensive
adolescents
POIHL 18S/6 03 0013 thrombosis research program
protect tarly warning and monitoring test systems in
thrombotic disease (human)
* ROIHL 18589 03 Psychosocial lactois and outcome in
coronary disease (human)
ROIHL 18632 02 Epidemiologic study ol chronic lung
disease
• POIHL 18645 03 0005 Biology of the artery wall and
atherosclerosis tttects ot atherosclerosis risk factors on
endothelium ot the primate
ROIHL 18687 03 Pathophysiology ot genetic
hypertriglycerinemias (human)
ROIHL 18723 03 Genetic heterogeneity of acid lipase
Atherosclerosis (human)
ROIHL 18776 04 Prevention of acute and fatal
cardiovascular disease (human)
ROIHL 18783 04 Detection and control of ventricular
premature beats (human)
ROIHL 18794 04 Prospective studies of conduction disease
(human)
ROIHL 1880004 Prospective study of resuscitated sudden
death victims (human)
ROIHL 18805O4 0001 Sudden cardiac death and the
onset ol myocardial infarction Predictive value of
maximum exercise stress testing (human)
R01HL1880504 0003 Sudden cardiac death and the
onset ol myocardial infarction Prediction from clinical and
laboratory assessments (human)
ROIHL 18805 04 0004 Sudden cardiac death and the
onset of myocardial infarction - Sudden death survivors-
Clinical follow-up and therapy (human)
ROIHL- 18805-04 0007 Sudden cardiac death and the
onset of myocardial infarction • Analysis of pathologic
factors involved in sudden death (human)
ROlHL-18907-03 Objective evaluation early after Ml and
heart surgery (human)
■ ROIHL- 1900 1-03 Atherosclerosis in bleeder and drug
treated subjects (pigs)
ROlHL-19018-03 Etiologic factors in cryptogenic fibrosing
alveolitis (human)
P50HL-191 70-02 0001 Harvard pulmonary SCOR-Chronic
diseases of the airways - Natural history, reversibility of
pulmonary abnormalities in smokers (human)
P50HL-19171-02 0005 Pulmonary SCOR-Lung injury by
childhood infections - Chronic respiratory disease of
children in North Carolina
' P50HL-19185-02 0006 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Evaluation of risk factors
in neonatal respiratory distress (human, sheep)
P50HL-19362-02 0002 A/S SCOR-Atherosclerosis In
nonhuman primates • Infant caloric intake, adipose tissue
development and atherosclerosis (baboon)
P50HL-19362-02 0003 A/S SCOR-Atherosclerosis in
nonhuman primates • Heritability of characters related to
atherosclerosis (baboons)
P50HL-19362-02 0006 A/S SCOR-Atherosclerosis in
nonhuman primates - Effects of cigarette smoking on
atherosclerosis (baboon)
P50HL-19362-02 0007 A/S SCOR-Atherosclerosis in
nonhuman primates - Behavior type, cigarette smoking and
atherosclerosis (baboon)
ROlHL-19567-03 Impact of emotion on coronary arteries
(human)
ROlHL-19839-09 Factors in youth predisposing to chronic
diseases (former college students)
ROlHL-19870-03 Hypertensive progeny-Physical and
humoral precursor search
ROlHL-19922-03 Childhood determinants of blood pressure
ROlHL-19930-03 A prospective study-Blood pressure in
newborn twins
ROlHL-19962-03
Tecumseh
R01HL-20034-03
High blood pressure in young people in
Hypertension-Psychophysiologic and
genetic precursors (human)
ROIHL-2007002 Alpha-1-antitrypsin deficiency (human,
hamsters)
ROlHL-2012402 Coronary risk factors (human)
ROlHL-201 59-03 Genetic epidemiology of precursors of
hypertension (human)
ROlHL-201 70-02 Pulmonary infection in splenectomized
animals (mice)
ROlHL-20238-02
(human)
ROlHL-20337-02
ROlHL-203 74-03
Prospective bundle branch block study
Thromboembolic diseases (human)
Myocardial function-Risk factors and
future CHO (human)
R01HL-20381-03 Long-term study of diabetic vascular
disease (human)
ROIHL-20418-03 Serum cholesterol binding reserve in
diabetes (human)
ROlHL-20428-03 The juvenile diabetic heart (human)
R01HL-20508-03 Diabetes, hyperglycemia and
cardiovascular disease (human)
179
ROIHI 20535 02 CardHivaicular dltoa%e and evolving
diabates mellilus (human)
ROIHL 20539 03 Blood glucose, hemoglobin Ale. and
diabetic vascular disease (human)
ROIHL 2063/ 02 Recovery after heart surgery Bio
behavioral (actors (human)
ROIHL 20645 01 Etiology ol myocardial infaction (human)
ROIHL 20655 02 Autonomic predictors ol hypertension in
children
ROIHL 20662 02 Physical activity, fitness and
epidemiology ol CHD
ROIHL 2080/ 02 Detection ol tamilia! hypercholesterolemia
(human)
ROIHL 20856 02 Platelet transfusions Usage and
complications (human)
ROIHL 20875 02 Chronic obstructive pulmonary disease
Familial/genetic (human)
ROIHL 20895 03 0010 Cineangiographic studies of
cardiovascular system Cortical necrosis and acute renal
failure (human, dogs. rats, rabbits)
ROIHL 2101002
40.000 persons
Glycemia. other traits and CV death in
Vascular lesions of diabetes in Oklahoma
Genetic patterns in deaths from Ml and
Antitrypsin and other causes of chronic
Acute renal failure following cardiac
ROIHL 21039 02
Indians
' R01HL2108802
stroke in Utah
ROIHL 21 156 02
lung disease
' ROIHL 212 10 01
surgery (human)
> ROlHL-2126002 Risk factor relationships of
atherosclerosis (monkeys)
ROlHL-21270 01 Correlation of arterial hemodynamics and
morphology (human)
ROlHL-21307 01 Risk reduction and exercise fitness in a
population
ROlHL-213 19-02 Interpersonal stress and coronary prone
behavior (human)
ROlHL-21352-02 Community studies of obstructive lung
disease (human)
' ROlHL-21527-01 Prospective study of bundle branch block
(human)
ROlHL-21674-01 Development of automatic implanted
defibrillator (dogs, cattle)
R18HL-21906 01 Stanford five city mulfifacfor risk
reduction study
ROlHL-219 12-01 Biosynthesis of lipoic acid and
atherosclerosis (birds, chick embryos)
ROlHL-21971-01 Atherosclerotic disease and risk factors
in twins (human)
R23HL-22004-01 Imaging and ECG studies in acute and
chronic IHD (human)
ROlHL-22255-01 The etiology/prevalence of peripheral
arterial disease (human)
ROlHL-22298-02 Origins of hypertension (human)
ROlHL-223 78-01 Psyco-somatic predictors of CHD In
adolescence (human)
ROlHL-22528-02 Early risk predictors for chronic
pulmonary disease (human)
ROlHL-22740-01 Behavior and cardiovascular disease-
Basic mechanisms (human)
ROlHL-2280901 Coronary-prone behavior and
cardiovascular reactivity (human)
ROlHL-22838-01
children
Post-transfusion hepatitis in newborn
Behavorial approaches to adolescent
* R18HL-22934-01
hypertension
' ROlHL-22982-01 Multicenter postcoronary risk
stratification program (human)
R01HL-23078-01 Psychosocial stress and sudden coronary
death (human)
ROlHL-23194-02 Genetics of hypertension and associated
variables (human)
ROlHL-239 70-01 Mechanisms and control of sudden
cardiac death (human, dog)
NOlHV-22971-07 Prevention of coronary heart disease
(human)
NOlHV-22977-08 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22979-07 Intervention trial for the prevention of
coronary heart disease (human)
NO lHV-229 80-06 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22981-10 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22982-07 Intervention trial for prevention of
coronary heart disease (human)
NOlHV-22983-07 Intervention trial for the prevention of
coronary heart disease (human)
NOIHV-33105-09 Intervention trial for prevention of
coronary heart disease (human)
NOlHV-33106-06 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-42931-07 Risk factor intervention trail for the
prevention of CHD (men)
NOlHV-42933-09 Multiple risk factors in coronary heart
disease (human)
NOlHV-530 10-03 NAS-NRC twin registry
NOlHV-62955-04 Data collection in clinical pathology and
morbid anatomy (men)
•Excludes routine methodok)gy OR covers only general projects which preclude indexing at the specific level
Oriented significantly to above subject.
M Grant has subprajects describing specific research aspects
See Appendix for investigator's name and grant number.
DM
DISEASE RECURRENCE
ROIHI IHH00(|4 I'Ki-.p.cllve itudy of ratu-.cilalol -.udd^n
death viclimi (tiuman)
ROIHL IBMO'j 04 0004 Sudden cardial death and tha
onint of myocardial infarclion Sudden death lurvivof.
Clinical lollow up and therapy (human)
ROIHI 18805 04 000/ Suddtn cardiac daalh and the
onset ol myocardial inlarction Analyiis ol pathologic
(actors involved in sudden death (human)
ROIHL 2142/ 0? Behavioral changes in pott inlarction
patients
DISEASE REGISTRIES (CLINICAL DISEASE)
SIE HEALTH RECORD SrStEMS. PAIKNI (DISEASE)
RECISIRIES
DISEASE REMISSION
"' P50HL 14164 07 0032 A/S SCOR Comparalive and
experimental atherosclerosis Plasma cholesterol, lesion
regression and vascular function (Rhesus monkey)
** P50HL 14164 07 0038 A/S SCOR Comparative and
experimental atherosclerosis Peripheral vascular studies
Cholesterol, lesion regression, vascular function
" P50HL 1423007 0094 A/S SCOR Lipids, atherosclerosis
and thrombosis Studies of atherosclerosis and regression
(monkeys)
" POIHL 14388 07 0233 Regulation of the circulation in
pathological states Pressure flow relationships after
regression of experimental atherosclerosis
" P50HL 15062 07 0018 Study of lipoproteins, artery wall.
and atherosclerosis Reversal of atherosclerosis in
monkeys
P50HL15062O7 0020 Study of lipoproteins, artery wall.
and atherosclerosis Artery wall reactions Elevated
pressure and hyperlipemia (monkey)
ROIHL 20535 02 Cardiovascular disease and evolving
diabetes mellitus (human)
DISEASE TRANSMISSION (COMMUNICABLE
DISEASE)
SEE COMMUNICABLE DISEASE TRANSMISSION
DISEASES, ACUTE (GENERAL)
POlHL-06285 18 0155 Cardiovascular-respiratory
physiology and biochemistry Therapeutic alterations,
contractile state in heart failure
POlHL-12738-10 0117 Physiologic pharmacology and its
clinical applications - Ventricular arrhythmias in ischemic
heart disease (human)
POlHL-14388-07 0188 Regulation of the circulation in
pathological states - Renin-angiotensin system in the sheep
fetus
ROlHL-15790-06 Follow-up study of acute coronary heart
attacks (human)
POlHL-16118-06 0003 Study of emphysema Degradation
of collagen and elastin (human, hamsters, mice)
" POlHL-17382-05 0003 Chemical mediators of acute
pulmonary disorders - Chemical mediators relevant to
allergic reactions (human, guinea pigs)
P50HL-17682-04 0001 Study of ischemic heart disease -
Studies in acute and chronic ischemic heart disease
(human)
P50HL-19170-02 0007 Harvard pulmonary SCOR-Chronic
diseases of the airways - Therapy effect on airway
obstruction in acute asthma (human)
" ROlHL-22982-01 Multicenter postcoronary risk
stratification program (human)
DISEASES, CHRONIC (GENERAL)
POlHL-06285-18 0155 Cardiovascular-respiratory
physiology and biochemistry - Therapeutic alterations.
contractile state in heart failure
ROlHL-09914-13 The myocardium in diabetes mellitus
(dogs, monkeys)
ROlHL-10612-13 0018 Humoral factors in heart failure
and hypertension - The pathogenesis of experimental renal
hypertension (dogs, rabbits, rats)
ROlHL-10612-13 0020 Humoral factors in heart failure
and hypertension - The control of renin release in the dog
P01HL-I1310-12 0080 Mechanisms of cardiovascular
disease - Metabolism of the hypertrophied myocardium
(human)
ROlHL-11802-10 Cardiovascular surgical research (dogs,
sheep, swine, cats, monkeys)
POlHL-14388-07 0224 Regulation of the circulation in
pathological states - Kallikrein-kinin system in hypertension
(human)
ROlHL-14720-08 Factors governing the renal excretion of
acid (humans, rats)
ROlHL-15047-06 Digital computer analysis of the
electrocardiogram (human)
P50HL- 17682-04 0001 Study of ischemic heart disease -
Studies in acute and chronic ischemic heart disease
(human)
P50HL-17682-04 0013 Study of ischemic heart disease -
Chronic ischemic heart disease-Myocardial function and
metabolism (dogs, swine)
ROlHL-17776-04 Pulmonary mucus transport in
obstructive lung diseases (human)
ROlHL-18599-02 Cardiovascular pharmacology of
ionophores (dogs)
ROlHL-18923-02 Steroid-induced hyperlipidemia and
hypertension (human, rats)
(contd)
DIS
ROlHL-1 9109-03 Regression of chronic atherosclerosis
(rabbits)
** P50HL 19171-02 0003 Pulmonary SCOR-Lung injury by
childhood infections - Natural history, host defense defects-
-Children with chronic pulmonary disease
ROlHL-19366-03 Renal Starling forces in experimental
conditions (rats, rabbits)
ROlHL-19451-03 0003 Functional characteristics of the
left heart - Left ventricular segmental contraction (human,
dogs)
** R23HL-1960101 Cardiac response to chronic metabolic
acidosis (rats)
ROlHL-19741-03 Murine CRD -A model of chronic
pulmonary inflammation (mice, rats)
R01HL19774-03 Pathogenesis of chronic lung disease
(rats, mice, bacteria)
** ROlHL-19839-09 Factors in youth predisposing to chronic
diseases (former college students)
ROlHL-20847-02 Respiratory neurochemical control
(human, goats)
ROlHL-21156-02
lung disease
ROlHL-21482-01
diabetes (rats)
R23HL-22575-01 Factors modifying cardiac digoxin effects
and content (dogs, cats)
R01HL-22676-0I Pathogenesis in experimental interstitial
pneumonitis (rabbits)
DISEASES, COMPLICATIONS
SEE ALSO NEOPLASMS, CANCER COMPLICATIONS OF
ROIHL 02965-22 Metabolism of plasma lipoproteins (rats,
chickens, human)
P01HL08974-14 0028 Natural and experimental
atherosclerosis - Geographic pathology of atherosclerosis
and coronary heart disease (human)
POlHL-1310809 0003 Clinical heart transplantation ■
Endomyocardial biopsy pathology
POlHL-1310809 0011 Clinical heart transplantation -
Humoral and cellular kinetics of allograft rejection (human)
** POlHL-13108-09 0014 Clinical heart transplantation ■
Platelets and coagulation in accelerated graft coronary
atherosclerosis
Newborn lung center for hyaline
Pulmonary status of children who had
180
Atherosclerosis in new modles of
DIS
Antitrypsin and other causes of chronic
Cardiac function and metabolism in
P50HL-1421407 0012
membrane disease
HMD as infants
P50HL-15092-07 0002 Immune and fibrotic response to
occupational environments - Longitudinal study of
sandblasters silicosis (human)
P60HL-15158-07 0011 Comprehensive sickle cell center •
Clinical services -Adult patients
P60HL-15158-07 0012 Comprehensive sickle cell center -
Clinical services -Pediatric patients
P60HL- 15 160-07 0009 Center for sickle cell disease -
Natural history of sickle cell disease (human)
P60HL-1516207 0021 Comprehensive sickle cell center -
Pneumococcal vaccine in sickle cell disease (children)
P60HL15168-07 0005 Comprehensive sickle cell disease
center - Ophthalmology (human, rabbits, monkeys)
P60HL-1 5169-05 0009 Support for center for sickle cell
disease - Infections in sickle cell anemia (human)
P60HL15169-05 0012 Support for center for sickle cell
disease - Evaluation of the incidence of cholelithiasis in
sickle cell disease (human)
P60HL15169-05 0014 Support for center for sickle cell
disease • Orthopaedic aspects of sickle cell disease
(human)
P60HL-1 5169-05 0017 Support for center for sickle cell
disease - Study of the natural history of sickle cell disease
in the home
P60HL-1 5170-05 0006 Support for center for sickle cell
anemia - Pediatric services -Comprehensive clinic
P60HL-15170-05 0019 Support for center for sickle cell
anemia • Renal handling of uric acid in sickle cell anemia
(human)
P60HL- 15996-06 0003 Cincinnati comprehensive sickle
cell center - Prophylactic penicillin in treatment of sickle
cell anemia (human)
P60HL-16005-05 0018 Comprehensive sickle cell center -
Comprehensive study -Natural history of sickle cell disease
in adults (human)
P60HL-1600806 0009 Wayne State University
comprehensive sickle cell center - Natural history of sickle
cell anemia (human)
ROlHL-17706-04 Psychosocial hypertension.
catecholamines and drugs (mice)
ROIHL 18020-04 Splanchnic hemodynamics in man
R01HL18923-02 Steroid-induced hyperlipidemia and
hypertension (human, rats)
P50HL19185-02 0007 Pulmonary SCOR -Neonatal
respiratory distress syndromes - Sodium bicarbonate and
albumin in resuscitation of preterm infants (human)
P50HL19185-02 0009 Pulmonary SCOR -Neonatal
respiratory distress syndromes Nasal continuous positive
airway pressure in hyaline membrane disease (human)
' P50HL-19185-G2 0011 Pulmonary SCOR -Neonatal
respiratory distress syndromes - Complications and
sequelae of neonatal respiratory distress (human)
ROIHL 2038103 Long-term study of diabetic vascular
disease (human)
ROlHL-20522-03 Peripheral arterial disease in the diabetic
(human)
Cardiac function and metabolism in
Natural history of the postphlebitic
ROlHL-21416-02
diabetes mellitus
ROlHL-21482-01
diabetes (rats)
** ROlHL-21572-01
syndrome
ROlHL-21829-01 Etiology of obstructive airway disease in
children (also monkeys)
R23HL-22004-01 Imaging and ECG studies in acute and
chronic IHD (human)
** ROlHL-22 110-02 Healing complications in vascular
grafting (dogs)
M P60HL-23282-01 Comprehensive hospital/community sickle
cell center
P60HL-23282-01 0002 Comprehensive hospital/community
sickle cell center ■ Clinical evaluation of alternate
pathaway of compliment activation
P60HL-23282-01 0003 Comprehensive hospital/community
sickle cell center - Treatment of sickle cell ulcers with
physical therapy and vitamin E (human)
** P60HL-2328201 0004 Comprehensive hospital/community
sickle cell center - Bacterial, viral and mycoplasmal
infections and sickle cell disease complications
ROlHL-2360301 Morphogenesis of hypertensive vascular
disease (rats)
DISEASES, COMPLICATIONS, ADHESIONS
** P01HL06312-17 0050 Surgical cardiology ■ Prevention of
pericardial and pleural adhesions by silicone oil (dogs)
POlHL-21584-02 0002 Respiratory mechanics in normal
and abnormal states - Lung mechanics -Regional
deformation and ventilation (dogs)
DISEASES, COMPLICATIONS, ANESTHESIA
RELATED
R01HL09609-11 Lung volume and breathing mechanics
during anesthesia (human)
P60HL-1 729204 0029 Vermont Lung Center ■ Computer-
assisted preoperative evaluation (human)
ROlHL-1735804 Ventilatory adjustments for optimal
oxygenation (dogs, rats)
P50HL 1766504 0026 Study of ischemic heart disease •
Anesthesia -Myocardial ischemia and hemodynamics in
coronary disease (human)
ROlHL-2075402 Anesthetic-induced myocardial depression
(rabbits)
DISEASES, COMPLICATIONS, POSTOPERATIVE
SEE ALSO DISEASES, COMPLICATIONS, POSTPERICARDIOTOMY
SYNDROME
SEE ALSO INJURIES. SURGICAL WOUND INFECTION
ROlHL-08696-15 0020 Orthotopic heart transplantation ■
Complete cardiopulmonary transplantation (dogs)
ROlHL-093 15-15 Coronary insufficiency and myocardial
revascularization (human, dogs)
ROlHL-0960911 Lung volume and breathing mechanics
during anesthesia (human)
POlHL-10539-12 0069 Pathophysiology of circulation ■
Ventricular compliance and mechanics in intact ventricles
(human)
" P01HL113 10-12 0095 Mechanisms of cardiovascular
disease - Blood and transfusion disorders (human, rats.
monkeys)
R01HL1190112 0001 Effects of metabolic surgery on
the hyperiipidemias - Partial ileal bypass (human)
ROlHL-1190112 0013 Effects of metabolic surgery on
the hypertipidemias - Human cholesterol and bile acids
dynamics -Ileal bypass
** ROlHL-11901-12 0018 Effects of metabolic surgery on
the hyperiipidemias ■ Jejunoileal bypass-Postoperative
complications (human)
R01HL1190112 0020 Effects of metabolic surgery on
the hypertipidemias ■ Jejuno-ileal bypass-Endogenous
animal model of obesity (rats)
** ROlHL-131 72-10 Post-trauma lung mechanics and fluid
exchange (human, dogs, monkeys)
** ROlHL-13754-08 Postoperative thromboembolism in
surgical patients (human)
ROlHL-14378-07 Lipemias and reconstructive cardiac
surgery (human)
ROlHL-15448-06 Surgical and metabolic aspects of
venous grafts, (dogs, monkeys, rabbits)
R01HL15593-05 Prolonged extracorporeal cardiopulmonary
support (rats, sheep, rabbits)
ROlHL-15676-06 The role of occult myocardial failure in
human shock (human, dogs)
ROlHL-16292-05 0018 Surgery and non-obstructive
coronary insufficiency ■ Unavoidable subendocardial
perfusion caused by venting and hypothermia (dogs)
R01HL16292-05 0019 Surgery and non-obstructive
coronary insufficiency • Distortion of subendocardial vessels
in infant hearts (dogs)
P60HL-17265-04 0007 Community blood resource center
support - Research-Massive transfusion and trauma
(human)
"* P60HL-1729204 0029 Vermont Lung Center • Computer-
assisted pre-operative evaluation (human)
ROlHL-17369-04 Arterial bypass surgery-Structure and
metabolism (monkeys)
** ROlHL-17821-03 Cavitation phenomena near prosthetic
devices
** ROlHL-18143-03 Surgery and pulmonary tissue alterations
(dogs, rats, human)
ROlHL-18288-04 Intraoperative protection of the
myocardium (dogs, rats)
ROlHL-18731-02 RES stimulating materials in
experimental shock (dogs)
R01HL18738-02 Prevention of postoperative venous
thrombi (human, cattle)
ROlHL-18762-03
(dogs)
Post-traumatic pulmonary insufficiency
Surgical vascular disorders (human.
ROlHL-18815-03
dogs)
R01HL19414-03 Protection of myocardium during cardiac
surgery (dogs, cats, human)
R01HL19818-02 Endocarditis on prosthetic heart valves
(rabbits, human)
ROlHL-19993-02 Optical detection of platelet aggregates
(human, baboons)
ROlHL-2008002
(dogs)
ROlHL-20170-02
animals (mice)
ROlHL-20226-02
physiology (dogs)
ROlHL-20637-02
Surgically induced myocardial edema
Pulmonary infection in splenectomized
Cardiac bypass and coronary collateral
Recovery after heart surgery -Bio-
behavioral factors (human)
** ROlHL-21533-02 Platelet inhibitor drug in coronary surgery
(human)
ROlHL-2 1786-01 Long-term effects of myocardial
protection (dogs, rats)
ROlHL-21969-01 Prevention of myocardial hypoxia during
by-pass (rats, mice, squirrels)
" ROlHL-22098-01 Is postoperative infarction due to
reperiusion injury? (human, dogs)
** ROlHL-22152-02 Ventricular dysfunction and cardiac
surgery (dogs)
** ROlHL-22445-01 Platelet inhibitors-Effect on coronary
bypass grafts (dogs)
ROlHL-22573-01 Treatment of post surgical
vasoconstriction (dogs, monkeys, human, rats)
ROlHL-2288801 Prosthetic valve endocarditis -Etiology
and therapy (dogs)
DISEASES, COMPLICATIONS,
POSTPERICARDIOTOMY SYNDROME
** ROlHL-16246-06 Immunologic studies in
postpericardiotomy syndrome (human)
P60HL-17269-04 0033 National heart and blood vessel
research and demonstration center - Autoallergic response
in cardiomyopathy, atherosclerosis, rheumatic heart disease
DISEASES, DISABLING
ROlHL-2206501 Intractability, medication, and coping
styles in asthma (human)
DISEASES, PATHOLOGIC PROCESSES (NOT
CLASSIFIED ELSEWHERE)
** ROlHL-039 19-20 The cell suface of streptococci (rats,
human)
** ROlHL-05875-18 Pathologic metabolic and physiologic
studies of heart (human, dogs, cats)
*• POlHL-06835-17 0040 Cardiovascular disease • Benign
and malignant phase of renal hypertension (dogs)
** POlHL-08805-15 0049 Regulation of ventilation and
pulmonary circulation ■ Pulmonary hypertension produced
by Dirofilaria immitis in the dog
** POlHL-0897414 0028 Natural and experimental
atherosclerosis ■ Geographic pathology of atherosclerosis
and coronary heart disease (human)
" ROlHL-10612-13 0018 Humoral factors in heart failure
and hypertension • The pathogenesis of experimental renal
hypertension (dogs, rabbits, rats)
** ROlHL-10612-13 0019 Humoral factors in heart failure
and hypertension - Pathogenesis of hypertension in the
spontaneous hypertensive rat
ROlHL-1177511 Platelet mechanisms in disease (human,
primates)
P50HL-14218-07 0006 Pulmonary SCOR-Newborn lung
center - Biochemical characteristics of the lung in RDS
(human, sheep)
POlHL-14388-07 0159 Regulation of the circulation in
pathological states - Early drug and diet interventions and
blood pressure development (rats)
P01HL14388-07 0161 Regulation of the circulation in
pathological states • Heterogeneity of left ventricular
pertusion in awake dogs
P01HL1438807 0163 Regulation of the circulation in
pathological states - Adrenergic receptors in coronary
vessels (dogs)
POlHL-14388-07 0168
pathological states ■
tissue culture)
POlHL-14388-07 0173
pathological states -
P01HL14388-07 0195
pathological states
Regulation of the circulation in
Ionic basis of depolarization (rats.
Regulation of the circulation in
Mechanisms of cardiac myosin ATPase
Regulation of the circulation in
General review of potential
pathophysiologic factors in spontaneous hypertension
ROlHL-16642-05 Biochemistry and pathophysiology of
plasma kallikrein (human, animals)
POlHL-1676905 0002 Pathobiologic and host defense
reactions in the lung - Pathogenesis ol complement
dependent injury to the lungs (rabbits)
POlHL-16769-05 0003 Pathobiologic and host defense
reactions in the lung - Pathobiologic mechanisms of
delayed sensitivity reactions in the lung (animals)
(contd)
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Onented significantly to above subject
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
DIS
181
Ltr,
*• POl HI 16/69 Ob 0004 Pnru.|.i,.i,.,:i, .mMin ,i ,i, i, n ..
ttictions in lh« lun| Pilhcujfin'ui ol l'\eiidniiioiij-. jnd
Sdiatii pnaumonias (rabbits)
POIHL W813 04 0001 luni ditiis* ind th* onyianition
ol blood and tissut Ditlusa intoistilial lung disaasa
Pathophysioloty Ibuman. dogj)
POINI 17813 04 000? lun( disease and Ihe oiygenation
ol blood and tissue Oiltuse inleislilial lung disease
Ultiasliuctutal abnoimahties (human)
ROIHL 18032 03 Development ol noimal and myopathic
mammalian heart (hamsters)
** R23HL 1961901 S«m and x ray analysis In human
pulmonary pathology
ROIHI. 2111S01 Prevention ol 02 toxicity with superoxide
dismutase (rats)
" ROIHL 21673 01 Pathophysiology ol venous changes in
hypertension (rats, rabbits, human, dogs)
** ROIHL 2273901 Evolution and progression ol pediatric
atherosclerosis
R23HL 22882 01 Modulation by disease ol ettect ot
lurosemide in man
DISEASES, PATHOLOGIC PROCESSES,
INFLAMMATION
ROIHL 10881 13 Structure and function ot
microcirculation (hamsters, rats. cats, dogs)
** POIHL 11310 12 0096 Mechanisms of cardiovascular
disease Complement chemistry and biology (human.
rabbits)
" ROIHL 13901 08 Ontogeny, ultcastructure, function in
lymphatic system (birds, fish, mammals)
** P50HL 1415307 0004 Johns Hopkins Lung Center
Chronic diseases of airways Macrophage enzymes in lung
injury, inflammation and repair (rabbit)
POIHL 1498S-07 0007 Adaptation to hypoxia - Control of
pulmonary circulation, histamine and the sympathetics
(animals)
POIHL 1519504 0004 Program project in biological
materials - Biological evaluation and surlace interaction
studies (dogs)
P50HL 1538907 0011 Pulmonary SCOR-Hypersensitivity
pneumonitis - Animal model-Hypersensitivity pneumonitis
in rabbits
ROlHL-15690-07 Hydrolytic enzymes of blood in health
and disease (human, animals)
P01HL15387-04 0009 The blood vessel and
thrombogenesis - Role of pituitary gland in the
pathogenesis of arteriosclerotic lesions (rats)
P01HL-167e9-05 0008 Pathobiologic and host defense
reactions in the lung ■ Pulmonary immunocytologic defense
mechanisms against bacteria (human, animals)
P60HL17265-04 0009 Community blood resource center
support • Research- Developing granulocyte transfusion
therapy (human, rabbit)
** P60HL-1726904 0033 National heart and blood vessel
research and demonstration center - Autoallergic response
in cardiomyopathy, atherosclerosis, rheumatic heart disease
ROlHL-1740405 Immunologic mechanisms in heart
disease (mice)
** POlHL-17417-05 0001 Experimentallung transplantation
- Mechanisms and mediators of lung allograft rejection
(dogs, mice)
** P50HL-17648-04 0023 Study of ischemic heart disease -
Chemical mediators of inflammation in acute myocardial
infarction (mammals)
ROlHL-17719'03 Lung injury, substrate utilization, oxygen
toxicity (rats, rabbits, dogs)
R01HL17964-04 The alternate pathvoy for fibrinolysis
(human)
ROlHL-18526-03
ROlHL-18826-04
in lung (human)
** POlHL-1882702 0006 Platelet vessel wall interactions in
thrombogenesis - Platelet immune injury in man
P50HL18828-03 0003 Specialized center of research in
thrombosis - Structure and function of plasma coagulation
inhibitors (human)
** P50HL-18828-03 0005 Specialized center of research in
thrombosis - Platelet inflammatory factors in thrombosis
(human, guinea pig)
P50HL18828-03 0006 Specialized center of research in
thrombosis - Etiology and pathogenesis of atherosclerosis
(rabbit, monkey, rat, human)
ROlHL-18936-02 Heart preservation and transplantation
studies (rat)
R0IHL-19374-03 Pharmacology of kinins in cardiovascular
disease (rats, rabbits)
** ROlHL-19685-03 Pathogenesis of inflammation of the lung
(guinea pigs)
POlHL-1971702 0021 Response of the lung to injury -
Gallium lung scans in fibrosing alveolitis (hamsters)
POlHL-1971702 0039 Response of the lung to injury -
Lung scanning in alveolitis and asbestolic interstitial
pneumonia (human, animal)
** R01HL19721-03 Lung intlammation-Lysosomal proteases
and liposomes (human, rabbits)
ROlHL-19731-03 Collagen in interstitial fibrosis of lung
(human)
** ROlHL-19732-03 Lymphokines in pulmonary
granulomatous inflammation (mice)
** R01HL19733-03 Absorption of antigen through inflamed
lungs (rabbits)
Kinins and the human lung
Interaction of peptides and target cells
*' KUIHI 19/41 03 Murine CRD A model ol (.hronic
pulmonary inflammation (mice, rats)
ROIHI 19/46 03 Proliferation and differentiation ol
alveolar macrophages (mice, hamsters)
ROIHL 19/// 03 Regulation of hypeisensilivily in Ihc lung
(rats, guinea pigs, rabbits, human!
ROIHI 19/95 03 Synthesis ot anaphyialoiic and
leucolactic peptides (human)
** ROIHL 19819 03 Mitogen induced interstitial pneumonitis
(rabbits)
" ROIHL 19836 03 Kinin inhibitors detected by use of
receptors (cattle)
*' ROIHL 20104 03 Pulmonary granulomatous inflammations
(mice)
ROIHL 20220 03 Anaphylatoxins as inflammatory and
chemotactic agents (guinea pig. rabbit, human)
** ROIHL 2046003 Aortic histamine synthesis in diabetes
(rat)
ROIHL 20783 02 Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
" POIHL 20994 02 0005 Dynamics of neutrophil elastase in
the lung Protease inhibitors in pulmonary inflammation
and emphysema (rabbits)
POIHL 20994 02 0008 Dynamics of neutrophil elastase in
the lung Structure function correlation in experimental
emphysema (human, dogs)
ROIHL'2137602 8lood gas barrier solute and water
transport (rabbits)
R01HL21544 02 Proteins of coagulation and Hageman
factor pathways (human, goats)
** ROIHL 21565 02 Pathogenesis of inflammatory lung injury
(rats, rabbits)
ROlHL-21843 01 Ischemia, diabetes and the
microcirculation (rats, cats, hamsters)
ROIHL 22257-01 Leukokinesis enhancing factor and lung
infections (human, rats)
** ROlHL-22301 01 Immunogenetics of chronic pulmonary
inflammation (mice)
ROlHL-22302-01 Immune responses in the human lung
(also rabbits, monkeys)
R23HL22437-01 Leukotactic mediators in lung
inflammatory reactions (rats, rabbits, human)
ROlHL-22555-01 Structure and function of platelet
activating factor (rabbits, human)
M POlHL-22602-01 Pathophysiology of the endothelium
** POlHL-2260201 0003 Pathophysiology of the
endothelium - Mechanisms of endothelial proliferation
(human, animals)
R23HL-22823'01 Phagocytic and immune defense
mechanisms of the lung (mice)
ROlHL-22924-01 The airway mucosal barrier (guinea pigs)
** ROlHL-2316101 0005 Biology of myocardial ischemia •
Localization of complement in myocardial infarction (dog)
** ROlHL-23586-06 Pharmacologic control of hypersensitivity
phenomena (human)
DISEASES, PATHOLOGIC PROCESSES,
INFLAMMATION, ABSCESS
ROlHL-20963-01 Experimental lung abscess (rabbits)
DISEASES, PATHOLOGIC PROCESSES,
INFLAAAMATION, ANTIINFLAMAAATORY
AGENTS
SEE ALSO CONNECTIVE TISSUE DISORDERS. RHEUMATIC
DISORDERS. ANTIRHEUMATIC AGENTS
SEE ALSO NEUROPHARMACOLOGICAL AGENTS, ANALGESICS.
ANTIPYRETICS
SEE ALSO PURINES-PYRIMIDINES METABOLISM ERRORS,
GOUT DRUGS
ROlHL-0506218 Lipid metabolism in cultured cells
(human, rats, rabbits)
P01HL06350-17 0019 Hemostasis research program
project - Microcirculation (human, rats, rabbits)
ROlHL-08399-15 Platelet injury in infections and allergic
diseases (human)
R01HL13036-08 Coronary thrombosis-Eflects on
myocardium and in vivo detection (dogs, monkeys)
ROlHL-13595-08 Renin and vascular hyper-reactivity in
hypertension (human, rats)
** P50HL-14147-08 0001 Specialized center of research in
thrombosis ■ Role of aspirin, other anti-platelet agents in
platelet function (rat. human)
ROlHL-14844-06 Mucous glycoprotein in human respiratory
epithelium (also wheat)
ROlHL-1489007 Platelet prostaglandins (human, rabbits)
R01HLI5698-12 Factors aftecting the action of
anticoagulants (rats, human)
POlHL-16411-04 0002 Blood systems in coagulation and
vessel disease - Early stages of coagulation and
cardiovascular disease (human, rabbits)
ROIHL-16437-05 Drug treatment of atherosclerosis
(rabbits, monkeys)
R01HL16496-04 Prostaglandins and renin experimental
hypertension (rabbits)
P50HL-1764804 0023 Study of ischemic heart disease -
Chemical mediators of inflammation in acute myocardial
infarction (mammals)
ROlHL-18204-03 Regional blood flow in viral myocarditis
(turkeys)
ROlHL-18245-03 Transition state analog inhibitors of
thrombin (human, cattle)
POlHL-18827-02 0006 Platelet vessel wall interactions in
thrombogenesis - Platelet immune injury in man
ROIHI I8S32 U3 brain mirror iiiulalion obdfvad iri vivo
attar trauma (inircl
ROIHI I922'i02 0001 lypct and mechanimi ot
pulmonary hypertension Slructural changei (human.
anirnals)
ROIHI 1923/03 Obtlructivt lung dlIMM and alveoUr
macrophages (human, animals)
ROIMI 19633 02 Pathogenesis and pharmacology ol lung
fibrosis (rats, rabbit-.)
ROIHI 19/21 03 Lung inflammation Lysosomal protaases
and liposomes (human, rabbits)
ROIHI 19/7/03 Regulation ol hypersensitivity in the lung
(rats, guinea pigs, rabbits, human)
ROIHL 19819 03
(rabbits)
ROIHL 20104 03
Mitogen induced interstitial pneumonitis
Pulmonary granulomaloui inflammations
'Excludes routine methodotogy OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject
(mice)
R23HL 21 1 16 02 Mechanisms of membrane and tissue
damage in lung (dogs, rabbits)
ROIHL 22444 01 Bronchial mucus production in organ
culture (human)
ROIHL 22527 01 Prostacyclin thromboxanes in the
cardiovascular system (human, rabbits)
ROIHL 22951 01 Studies on the affect of vitamin E on
platelets (human, rats)
DISEASES, PATHOLOGIC PROCESSES,
INFLAiMAAATION, FOREIGN BODY (REACTION)
SEE ALSO TISSUE COMPATIBILITY TRANSPLANT. IMPUNT
ROIHL 1941903 Cellular interactions with foreign
materials (mammals)
ROIHL 19711-03 Lymphokines in pulmonary granulomas
(guinea pigs)
DISEASES, PATHOLOGIC PROCESSES,
IRRITATION (IRRITANTS)
SEE ALSO NEOPUSTIC TRANSFORMATION
POlHL-06285-18 0188 Cardiovascular-respiratory
physiology and biochemistry Physiology and pharmacology
in regulation of airways hyperirritability (animals)
ROIHL 20783 02 Airway reactivity -8-adrenoceptors and
prostaglandins (guinea pigs)
R23HL 21369-02 Tracheal mucin synthesis in experimental
bronchitis (rats)
DISEASES, PATHOLOGIC PROCESSES,
IRRITATION, FIBROSING AGENTS
ROlHL-19658-03 Biochemistry of lung connective tissue
(rats)
ROlHL-19720-03 Evaluation of anti-fibrotic agents in
pulmonary fibrosis (rats)
" ROlHL-20095-03 Role of lymphokines and monocytes in
lung fibrosis (human, guinea pigs, rats)
DISEASES, PATHOLOGIC PROCESSES, NECROSIS
SEE ALSO CARDIOVASCULAR DISORDERS. INFARCTION
SEE ALSO CELL DEATH
SEE ALSO DISEASES. PATHOLOGIC PROCESSES. NECROSIS.
GANGRENE (GENERAL)
SEE ALSO KIDNEY DISORDERS. KIDNEY NECROSIS
SEE ALSO MUSCULAR DISORDERS. MUSCLE NECROSIS
SEE ALSO SKELETAL DISORDERS. BONE NECROSIS
POlHL-0628518 0143 Cardiovascular-respiratory
physiology and biochemistry - Myocardial ischemia (human,
dogs, lambs)
** POlHL-06370-17 0015 Cardiopulmonary and renal
pathology research center - Pathogenesis of chemically
induced tissue injury (rats)
** POlHL-07896-15 0046 Environmental biomedical research
program ■ Treatment of radiation induced tissue injury by
hyperbaric oxygen (human)
R01HL-17404-05 Immunologic mechanisms in heart
disease (mice)
P50HL-1768204 0013 Study of ischemic heart disease -
Chronic ischemic heart disease-Myocardial function and
metabolism (dogs, swine)
ROlHL-20648-01 Physical factors and coronary flow (dogs)
ROlHL-2175002 Electrocardiographic quantification of
infarct size (dogs, human)
ROlHL-21786-01 Long-term effects of myocardial
protection (dogs, rats)
ROlHL-22098-01 Is postoperative infarction due to
reperfusion injury? (human, dogs)
" ROlHL-23981-01 Acute alveolar injury (dogs)
DISEASES, PATHOLOGIC PROCESSES, NECROSIS,
GANGRENE (GENERAL)
ROlHL-22113-02 Micro/macrovasculature in healing of
foot lesions (human)
DISEASES, PATHOLOGY (GENERAL)*
SEE ALSO HISTOPATHOLOGY (GENERAL)*
SEE ALSO PATHOLOGY STUDY SECTION
POlHL-03174-23 0002 Mechanisms of acute vascular
reaction to injury - Chemical structure, pathological
significance of amyloid substance (human, mice)
** POlHL-0631417 0048 Immunologic mechanisms in
cardiovascular disease - Pathogenesis of glomerulonephritis
(rats, mice)
ROlHL-07605-16 Congenital heart disease research
program (human, dogs)
** P01HL13738-08 0003 Cardiac assist devices and
artificial hearts - Pathophysiological effects of the artificial
heart (calves)
(contd)
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
DIS
P50HL-14136-07 9003 Pulmonary SCOR-Airways
obstructive diseases - Pathology core (human, dogs)
P50HL-14153-07 0019 Johns Hopkins Lung Center-
Chronic diseases of airways - Pathology core (human,
animal)
P50HL-14164-07 0026 A/S SCOR-Comparative and
experimental atherosclerosis ■ Comparative pathology unit
(pigeons, monkeys)
P50HL-14187-07 0016 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses - Core
pathology service (dogs, rabbits, human)
P50HL14212-07 0011 Correlated studies of pulmonary
fibrosis - Pathology core (human, animal)
P50HL-14212-07 0012 Correlated studies of pulmonary
fibrosis - Inorganic particulates in tobacco, smoke and
lungs of cigarette smokers (human)
POlHL-14388-07 0151 Regulation of the circulation in
pathological states - Catecholamine release in potassium
ionfree contractures in the caudal artery
P01HL14388-07 0152
pathological states
SHR
P01HL14388-07 0153
pathological states
(rats)
POlHL-14388-07 0154
pathological states
contraction (rats)
POlHL-14388-07 0155
pathological states
Regulation of the circulation in
Ion flux alterations in caudal artery in
Regulation of the circulation in
Subcellular distribution of calcium
Regulation of the circulation in
Energetics of smooth muscle
Regulation of the circulation in
Cardiopulmonary afferent activity,
carotid chemobaroreceptor reflexes
P01HL14388-07 0156 Regulation of the circulation in
pathological states ■ Blood pressure with drinking to
intracranial angiotensin II injections (rats)
P01HL14388-07 0157 Regulation of the circulation in
pathological states - Autoregulation of renal blood flow and
distribution in sodium excretion control
POlHL-14388-07 0158 Regulation of the circulation in
pathological states - Developmental aspect of abnormal
vascular reactivity (rats)
P50HL-1510307 0001 A/S SCOR-Early natural history of
arteriosclerosis ■ Clinical research-Bogalusa heart study
(children)
P50HL 1538907 0009 Pulmonary SCOR-Hypersensitivity
pneumonitis ■ Clinical studies-Pulmonary mycotoxicosis
" P50HL- 15389-07 0018 Pulmonary SCOR-Hypersensitivity
pneumonitis • Pathology core (human, animal)
P60HL-1 7269-04 0001 National heart and blood vessel
research and demonstration center - Atherosclerosis-
Arterial pathology and plasma lipids (human)
P60HL-17269-04 0004 National heart and blood vessel
research and demonstration center - Atherosclerosis-
Clinical surgical aspects (human)
P60HL-17269-04 0048 National heart and blood vessel
research and demonstration center - Atherosclerosis-
Lipoproteins and the arterial wall (human)
*• ROlHL-1 7532-04 Infarct size-ECG, angio, path, correlation
in dogs
ROlHL-17581-03 Patent ductus arteriosus and pulmonary
hypertension (dogs)
** P50HL-1 7646-04 0003 Study of ischemic heart disease -
Core pathology facility (human, dogs)
** P50HL-17648-04 0020 Study of ischemic heart disease -
Core pathology laboratory-lschemic heart disease (human,
animal)
** P50HL-17655-04 0010 Study of ischemic heart disease -
Core facility-Cardiovascular pathology (human, animal)
** P50HL-17665-04 0028 Study of ischemic heart disease ■
Pathologic and biochemical studies of ischemic
myocardium (human, dog)
** P50HL17667-04 0045 Study of ischemic heart disease -
Pathology of myocardial Ischemic necrosis (human)
** P50HL-1 7669-04 0022 Ischemic heart disease center
(SCOR) ■ Pathological studies of human and experimental
ischemic heart disease
** P50HL-1 7670-04 0016 Study of ischemic heart disease ■
Core pathology laboratory (human, dogs, monkeys)
" P50HL-1 7682-04 0012 Study of ischemic heart disease ■
Pathology core laboratory (human)
** ROIHL 17873-04 Pathophysiology of exercise-induced
asthma (human)
** ROlHL-18805-04 0007 Sudden cardiac death and the
onset of myocardial infarction - Analysis of pathologic
factors involved in sudden death (human)
R01HL19255-03 Evaluation of diagnostic clinical
hemorrheology (human)
" P50HL19362-02 0015 A/S SCOR-Atherosclerosis in
nonhuman primates Core laboratory-Pathology and
morphometry (baboons)
** ROlHL-21684-02 0003 Radionuclide infarct sizing and
therapy evaluation - Core pathology laboratory (dogs,
human)
NOlHR-62943-05 Nocturnal oxygen therapy in chronic
hypoxic lung disease (human)
DISEASES, PROGNOSIS
P01HL-04664-18 0015 Cardiovascular and lung dynamics
- Computer system for the cardiovascular laboratory
** POlHL-06835-17 0048 Cardiovascular disease •
Aldosterone producing adenoma prediction of curability
(human)
** POlHL-06835-17 0052 Cardiovascular disease Aortic
distensibility (human)
182
ROlHL-0947411 Natural history-congenital heart defects-
Joint study (human)
POlHL-10436-13 0001 A multidisciplinary study of
congenital heart disease - Assessment of the outlook for
children with congenital heart disease
ROlHL-10445-09 Cooperative study of drugs and coronary
heart disease (men)
POlHL-10539-12 0031 Pathophysiology of circulation -
Post myocardial infarction care-Psychological aspects
(human)
ROlHL-10705-09 Cooperative study of drugs and coronary
heart disease (men)
ROlHL-107 18-10 Natural history of congenital heart
defects-Joint study (human)
POlHL-11310 12 0073 Mechanisms of cardiovascular
disease - Electrophysiological study of atrial fibrillation
(human)
POlHL-1131012 0083 Mechanisms of cardiovascular
disease - Ventricular volume and hemodynamics in adult
congenital heart disease
POlHL-1 13 10-12 0091 Mechanisms of cardiovascular
disease - Noninvasive techniques in cardiovascular
diagnosis (human)
P01HL11310-12 0092 Mechanisms of cardiovascular
disease - Exercise electrophysiology (human)
ROIHLI 1372-08 Cooperative study of drugs and coronary
heart disease (men)
ROlHL-1254207 Natural history, congenital heart defects-
Joint study (human)
' ROlHL-12611-10 Basic and clinical studies of the ST-T
deflection (human, dogs)
POlHL-1273810 0117 Physiologic pharmacology and its
clinical applications - Ventricular arrhythmias in ischemic
heart disease (human)
ROlHL-12833-09 Genetic and environmental influences on
lung disease (human)
' POlHL-13 108-09 0001 Clinical heart transplantation -
Therapy and prognosis (human)
■ POlHL-13108-09 0009 Clinical heart transplantation • B
cell alloantigens in cardiac allograft compatibility (human)
' POlHL-13108-09 0010 Clinical heart transplantation -
Serum factors inhibiting lymphocyte responses in MLC
(human, bush babies)
P50HL-142 14-07 0012 Newborn lung center for hyaline
membrane disease - Pulmonary status of children who had
HMD as infants
P50HL-142 14-07 0013 Newborn lung center for hyaline
membrane disease Developmental outcome of children
who had HMD as infants
P50HL-14214-07 0032 Newborn lung center for hyaline
membrane disease - Evoked electroencephalographic
potential in infants with HMD (human)
* P50HL-142 14-07 0033 Newborn lung center for hyaline
membrane disease - Statistical modeling, predictive
classification in clinical management of HMD
* P50HL-142 18-07 0012 Pulmonary SCOR-Newborn lung
center - Longitudinal study of RDS-On-line fetal and
neonatal monitoring (human)
P60HL-15160-07 0009 Center for sickle cell disease ■
Natural history of sickle cell disease (human)
ROlHL-151 74-06 CV disease epidemiology-Second
generation studies (human)
ROlHL-15526-05 Respiratory mechanics in children
P60HL-16005-05 0018 Comprehensive sickle cell center -
Comprehensive study-Natural history of sickle cell disease
in adults (human)
P60HL-16008-06 0009 Wayne State University
comprehensive sickle cell center - Natural history of sickle
cell anemia (human)
ROlHL-16403-05 Prognostication by computer-Analyzed
vectorcardiogram (human)
ROlHL-16908-04 Myocardial function, risk factors and
future CHO (men)
R01HL-I7408-03 Fresh blood rheology-Relation to
cardiovascular risk (human)
* ROlHL-17532-04 Infarct size-ECG, angio, path, correlation
in dogs
P50HL-17646-04 0001 Study of ischemic heart disease -
Core clinical investigation unit
P50HL-17646-04 0015 Study of ischemic heart disease -
Protecting ischemic myocardium in patients with evolving
myocardial infarction
P50HL-17651-04 0032 Ischemic heart disease specialized
center of research - Cardiovascular surgery core (human,
dogs)
P50HL 17651-04 0039 Ischemic heart disease specialized
center of research • Measurement and prediction of infarct
size (human, dog)
P50HL-17651-04 0046 Ischemic heart disease specialized
center of research - Clinical core-Physiological
changes/biochemical effects of myocardial ischemia
P50HL-17655-04 0004 Study of ischemic heart disease ■
Coronary arteriography in survivors of acute myocardial
infarction (human)
P50HL-17667-04 0001 Study of ischemic heart disease -
Natural history of ischemic heart disease (human)
P50HL-17669-04 0013 Ischemic heart disease center
(SCOR) • Exercise in patients with ischemic heart disease
R25HL-184 14-03 Hypertension-Family strategies for
patient adherence
R01HL18632-02 Epidemiologic study of chronic lung
disease
OMI
ROlHL-18683-03 Left ventricle function in aortic
regurgitation (human)
R01HL18783-04 Detection and control of ventricular
premature beats (human)
ROlHL-18800-04 Prospective study of resuscitated sudden
death victims (human)
ROIHL- 18805-04 0003 Sudden cardiac death and the
onset of myocardial infarction - Prediction from clinical and
laboratory assessments (human)
ROlHL-18805-04 0004 Sudden cardiac death and the
onset of myocardial infarction - Sudden death survivors-
Clinical follow-up and therapy (human)
ROIHL- 18808-04 0001 Prediction and prevention of
sudden cardiac death - Prognostic significance of
premature ventricular contractions (human)
" P50HL 1917002 0001 Harvard pulmonary SCOR -Chronic
diseases of the airways - Natural history, reversibility of
pulmonary abnormalities in smokers (human)
P50HL-19187-02 0007 Pediatric pulmonary SCOR -Hyaline
membrane disease - Follow-up study-Infants with hyaline
membrane disease (human)
ROlHL-19255-03 Evaluation of diagnostic clinical
hemorrheology (human)
ROIHL 19858-03 UMMC-Blood pressure precursors and
consequences (human)
" ROIHL 2037403 Myocardial function-Risk factors and
future CHO (human)
ROlHL-21527-01 Prospective study of bundle branch block
(human)
ROIHL 22065-01 Intractability, medication, and coping
styles in asthma (human)
ROIHL'22113-02 Micro/macrovasculature In healing of
foot lesions (human)
ROlHL-22378-01 Psyco-somatic predictors of CHD in
adolescence (human)
" N01HR-32902-07 Pilot study to standardize the
measurement of closing volume (human)
NOlHR-32903-n Pilot study to standardize the
measurement of closing volume' (human)
NOlHV-53015-09 Establishment of a lipid research clinic
(human)
DISEASES, SIGNS-SYMPTOMS (NOT GROUPED
ELSEWHERE)
SEE ALSO NEUROLOGIC MANIFESTATIONS
NO lHB-729 16-02 Crisis and pain symptom prophylaxis by
oral zinc therapy (human)
POlHL-11310-12 0067 Mechanisms of cardiovascular
disease - Cardiac pertormance with measured
homodynamic variables (human)
ROlHL-18175-03 Drug taking for hypertension in a rural
community
DISEASES, SIGNS-SYMPTOMS, HIRSUTISM
R01HL19644-03 Etiological factors in hypertension
(human, dogs, rats)
DISEASES, SYNDROMES NOT LISTED ELSEWHERE,
GOODPASTURE'S SYNDROME
POlHL-06314-17 0063 Immunologic mechanisms in
cardiovascular disease - Glomerular cells in tissue culture
(human)
DISOPYRAMIDE
SEE PYRIDINAMIDES, DISOPYRAMIDE
DISSOCIATION (REACTIONS) CHEMISTRY
SEE CHEMICAL REACTIONS, DISSOCIATION
DISSOLVED HYDROGEN BLOOD FLOW
MEASUREMENT
SEE CARDIOVASCULAR DISORDERS DIAGNOSIS, BLOOD FLOW
MEASUREMENTS, HYDROGEN*
DISULFIDE BONDS
SEE CHEMICAL BONOS, DISULFIDE BONOS
DISULFIDES
SEE SULFIDES, DISULFIDES
DISULFIRAM
SEE THIOCARBAMATES, DISULFIRAM
DIURESIS
SEE KIDNEY FUNCTION, DIURESIS
DIURETICS
SEE KIDNEY FUNCTION, DIURETICS
DIURNAL VARIATION
SEE BIOPERIODICITY, CIRCADIAN RHYTHMS
DIVALENT CATIONS
SEE IONS, CATIONS, DIVALENT
DIVALENT METALS
SEE METALS, DIVALENT METALS
DIVERTICUUTIS, GASTROINTESTINAL (GENERAL)
SEE GASTROINTESTINAL DISORDERS, DIVERTICULITIS
DIVING
SEE WATER ENVIRONMENT, DIVING AND SWIMMING
DIVING REFLEX
SEE WATER ENVIRONMENT, DIVING REFLEX
i
•Excludes routine methodotogy OR covers only general projects which preclude indexing at the specific level.
**Oiiented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
i
DNA
DMI
SEE AnPINES. DESIPRAMINF
ONA
SH NIICKIC ACIOS ONA
DNA, RECOMBINANT
SEE NUCLEIC ACIOS. UNNAIURAl NUClfIC ACIOS HYBRID
NUCLEIC ACIOS
ONA, RECOMBINANT, ARTIFICIAUV INDUCED
SEF GLNETIC MANIPULAIION
DNA BIOSYNTHESIS
SEE NUCLEIC ACIOS SYNIHESIS, ONA
DNA CIRCULAR
see: nucleic acids, dna circuur
DNA LIGASE (REPAIRASE)
SEE NUCLEIC ACIDS REPAIR. ONA REPAIR (ENZYME)
DNA MANIPULATION (TRANSFER TO FOREIGN
HOSTS)
SEE GENETIC MANIPULATION
DNA MITOCHONDRIAL
SEE NUCLEIC ACIDS. MT ONA
DNA NUCLEOTIDYLTRANSFERASE
SEE NUCLEOTIDYLTRANSFERASES. DNA
NUCLEOTIDYLTRANSFERASES
DNA POLYMERASE
SEE NUCLEOTIDYLTRANSFERASES. ONA
NUCLEOTIDYLTRANSFERASES
DNA REPAIR (ENZYMES)
SEE NUCLEIC ACIDS REPAIR, DNA REPAIR (ENZYME)
DNA REPLICATION
SEE NUCLEIC ACIDS SYNTHESIS. DNA
DNA TRANSFER, ARTIFICIALLY INDUCED
SEE GENETIC MANIPUUTION
DOBUTAMINE
SEE PHENYLALKYLAMINES. CATECHOUMINES. DOBUTAMINE
DOCUMENTATION SYSTEMS
SEE INFORMATION SYSTEMS (INCL BANKS AND CENTERS)
DOGS
SEE MAMMALS. CARNIVORES. DOGS'
DOHP (DIOLEYLPHOSPHATE) MODEL
SEE BIOLOGICAL TRANSPORT. MEMBRANE MODELS
DONNAN EFFECT ON CELLS
SEE CELL FLUIDS. OSMOTIC PRESSURE
DONORS
SEE BLOOD TRANSFUSION. BLOOD DONORS
SEE TISSUE DONORS
DOPA
SEE CYCLIC AMINO ACIDS. DOPA
DOPAMINE
SEE PHENYULKYLAMINES. CATECHOLAMINES. DOPAMINE
DOPAMINE (BETA)-HYDROXYLASE
SEE OXYGENASES. DOPAMINE (BETA).MONOOXYGENASE
DOPAMINE (BETA)-MONOOXYGENASE
SEE OXYGENASES. DOPAMINE (BETA)-MONOOXYGENASE
DOPAMINERGIC RECEPTORS
SEE NEUROTRANSMITTERS RECEPTORS. ADRENERGIC
RECEPTORS. DOPAMINERGIC RECEPTORS
DORAAANT VIRUS DISEASES
SEE VIRUS DISEASE CHARACTERISTICS. UTENT DORMANT
OR SLOW
DOSAGE
SEE DOSAGE AND ROUTE, DOSAGE
DOSAGE AND ROUTE, DOSAGE
SEE ALSO DRUGS, PHARMACOLOGY. BIOAVAILABILITY
SEE ALSO DRUGS ABUSE. OVERDOSE
POlHL-07896-15 0029 Environmental biomedical research
program - Oxygen-helium diving resulting in high pressure
nervous syndrome (human, animals)
ROlHL-08696-15 0001 Orthotopic heart transplantation •
Transplantation immunology-Antithymocyte globulin
(rabbits, monkeys)
M POlHL-08899-14 Tolerance to respiratory gases in health
and disease
POlHL-08899-14 0007 Tolerance to respiratory gases in
health and disease ■ Effects of high oxygen pressures on
visual function (human, animals)
** P01HL-0889914 0039 Tolerance to respiratory gases in
health and disease ■ Dose-response studies of oxygen on
C02 reactivity in brain vessels (human)
" POlHL-08899-14 0048 Tolerance to respiratory gases in
health and disease - Changes in human vision during
known tolerable exposures
IHJ
" POIHL 0889<l 14 0049 lolirance to rMplriloiy |iiii In
hniilth and ditruMi Doig rasponsc mMsuret ol Mvttt
o>v|iin loiK ity (monknys)
POIHL 08899 14 OUSI loleranca to raspiralory |a>ai in
health and disensp Oiyurn elfecis upon iiolittd retinal
matabolnm (luhliils. mankoy^)
POIHl 08899 14 OUbb lol«iance lo respiratory gases in
health and disease Adaplalion and ellecls of narcotic
gases exposure (human)
ROIHI 089/; 14 QuanltUtion of How and solute llui in
microvesssis (cats, rals)
ROIHL 10834 09 Fetal and neonatal pulmonary circulation
(goals)
ROIHL I09M II Neural control ol the heart (dogs, rats)
POIHL 113bl 12 0010 Cellular and molecular
mechanisms ol myocardial (unction Basic ionic exchange
studies (lats)
POIHL 12373 10 0013 Cardiopulmonary physiology and
pathophysiology Effects ol cardiovascular drugs on left
ventricular (unction (dogs)
ROIHL 12421 10 Pathophysiology of circulatory shock
(dogs, baboons)
POIHL 12738 10 0065 Physiologic pharmacology and its
clinical applications Psychotheropeutic drugs and
cardiovascular system (human, rals)
ROIHL 14944 07 Renal vascular reactivity in hypertensive
patient
P50HL 15092 07 0001 Immune and librotic response to
occupational environments X ray diffraction study Dust
exposure in asbestos cement products manulacturing
ROIHL 15190-07 Physiological basis ol arrhythmias and
their therapy (human)
R01HL15444 06 Neonatal development ol adrenergic
receptor mechanisms (pigs)
ROlHL-15526-05 Respiratory mechanics in children
ROIHL 16361 03 Fibrin complexes in intermediary
coagulation (human, rabbits)
POIHL- 18646-03 0001 Studies basic to heart
transplantation Individualized regulation of
immunosuppression (dogs, rats)
ROIHL 18923-02 Steroid-induced hyperlipidemia and
hypertension (human, rats)
ROIHL 1910502 Detection and adherence of fibrin
monomer complexes (human)
P50HL-19170-02 0004 Harvard pulmonary SCOR-Chronic
diseases of the airways - Exercise, increased ventilation
effect on airway exposure and responses (rodent)
P01HL19242-02 0004 Study of vascular smooth muscle -
Cyclic nucleotide metabolism in smooth muscle cultures
(human, rats)
ROlHL-20783-02 Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
POlHL-20993-02 0008 Population dynamics of arterial
cells in atherogenesis - Angiotoxicity of cholesterol
oxidation in atherogenesis (rabbits)
ROlHL-211 15-01 Prevention of 02 toxicity with superoxide
dismutase (rats)
ROlHL-22603-01 Trace metals, vascular activity and
hypertension (rats)
R23HL-22882-01 Modulation by disease of effect of
furosemide in man
DOSAGE AND ROUTE, INFUSIONS ARTERIAL
ROlHL-14826-05 External isotope assay of atherosclerosis
(rats, rabbits)
ROlHL-15681-06 Coronary flow studies of partially
obstructed vessels (dogs)
DOSAGE AND ROUTE, INFUSIONS VENOUS
P01HL10436-13 0005 A multidisciplinary study of
congenital heart disease Pulmonary physiology in
congenital heart disease (human)
POlHL-15486-06 0006 Studies on thrombosis ■ Clinical
investigation unit
ROlHL-19289-03 Assessment of infusion methods for
myocardial mapping (dogs)
ROlHL-19898-03 Desferrioxamine therapy in thalassemia
(dogs. rats, children)
ROlHL-20000-03 Iron overload in homozygous beta
thalassemia (human)
ROlHL-224 17-01 Microprocessors in medical applications
(dogs)
DOSAGE AND ROUTE, INHALATION
SEE ALSO SENSORY DEPRESSION. ANESTHESIA (GENERAL)
INHAUTION
P50HL-I42 12-07 0015 Correlated studies of pulmonary
fibrosis - Pulmonary defense mechanisms and librotic lung
disease (rodents, rabbits)
P50HL-191 70-02 0004 Harvard pulmonary SCOR-Chronic
diseases of the airways - Exercise, increased ventilation
effect on airway exposure and responses (rodent)
** R01HL19647-03 Therapeutic aerosols
ROlHL-19720-03 Evaluation of anti-librotic agents in
pulmonary librosis (rats)
ROlHL-2227301 Oral and lung absorption ol nitroglycerin
(rats)
DOSAGE AND ROUTE, INJECTIONS,
MICROINJECTIONS
ROlHL-12827-08 Regulation ol sodium excretion (dogs
rats)
DOS
DOSAGE AND ROUTE, ISOLATION PERFUSION
MOIHl 0'j883 18 0001 Reflei rontrol of letislanca and
capacitance vessels Naturally occurrinf vaioaclive
substances and the vascular neuroelleclori (dofl
POIHl 06285 18 0I4'> Cardiovascular retpiialory
physiology and biochemistry Pulmonary, pleural end
systemic microcirculation (animals)
ROIHI 0869G 15 0UI2 Urihotopii; heart transplantation
Transplantation immunology Modulation ol donor
antigenicity (dogs)
ROIHI 08696 15 0013 Orthotopic heart liansplantation
Transplantation immunology -Cardiac heterotraniplantation
(rabbits, dogs)
ROIHI 126// 10 Surgical physiologic studies of itolaled
kidneys (dogs, rats)
ROIHI 128/9 09 0010 Pulmonary transport and
metabolism in vivo Lung morphometry in control ind
edematous lungs (dogs)
ROIHL 1331508 Disposition ol vasoactive hormones in
mammalian lung (rats, rabbits, human)
POIHL 15835 06 0013 Study of muscles related lo heart
disease Cardiac bioenergetics (rats)
•* POIHL 1/8/1 04 0013 Kidney, sodium, cardiac output.
arterioles and hypertension Perfusion pressure and renal
sodium excretion (rals)
ROIHL 1/94403 Studies in lung preserva..^., .dogs)
POIHL 1864603 0010 Studies basic lo heart
transplantation Development and study ol a heart
preservation chamber (dogs, sheep)
ROIHL 20219 02 Cryopreservalion ol the isolated heart
(rals)
ROIHL 20344 02 Regulation ol protein turnover in lung
tissue (rats)
ROIHL 21684 02 0002 Radionuclide inlarct sizing and
therapy evaluation Evaluating myocardial imaging agents
in global and regional ischemia (rabbits)
DOSAGE AND ROUTE, PERFUSION
SEE ALSO BLOOD TREATMENT. WHOLE BODY PERFUSION
(BLOOD REPLACEMENT)
ROlHL-03181 21 0025 Hemodynamics as applied to
surgical problems Vascular stenosis (dogs)
POlHL-06285-18 0197 Cardiovascular-respiratory
physiology and biochemistry Microperfusion and
micropuncturc of renal tubules (hamsters, desert rats)
** P01HL-06312-17 0032 Surgical cardiology - Preservation
of the heart by perfusion (dogs)
POIHL 06312-17 0052 Surgical cardiology Assay of
metabolic variables ol rat heart
POlHL-08805-15 0025 Regulation ol ventilation and
pulmonary circulation ■ Pulmonary edema (rabbits)
POlHL-08805-15 0048 Regulation of ventilation and
pulmonary circulation • Permeability ol alveolo -Capillary
membrane in normal pulmonary hypertensive lung
*• P01HL14388-07 0161 Regulation ol the circulation in
pathological states - Heterogeneity of left ventricular
perfusion in awake dogs
" P01HL1438807 0162 Regulation ol the circulation in
pathological states - Phasic coronary flow and myocardial
perfusion in aortic regurgitation (dogs)
ROlHL-1552006 Total blood replacement by fluorocarbons
and polyols (rats)
P50HL-17648-04 0012 Study ol ischemic heart disease ■
Retrograde coronary venous perfusion -Acute myocardial
ischemia
P50HL-I7651-04 0016 Ischemic heart disease specialized
center of research ■ Retroperlusion of coronary venus
circulation with therapeutic agents (dogs)
P50HL-17651-04 0043 Ischemic heart disease specialized
center ol research - Gradual reperfusion following acute
coronary occlusion (dog)
ROlHL-18952-03 Metabolism in perfused letal and
newborn rabbit lungs
** ROlHL-20073-02 Blood compatible materials by fluid
perfusion (human, dogs)
ROlHL-2111501 Prevention of 02 toxicity with superoxide
dismutase (rats)
R23HL-2244801
perfusion (rats)
ROlHL-22500-01
Modulation of heart graft antigenicity by
•Excludes routine methodology OR covers only general projects which preclude indexing
Oiiented significantly to above subject.
at the specilic level.
M Grant has subprojects descnbing specific researcli aspects.
See Appendix for investigator's name and grant number.
Conversion of choline to
phosphatidylcholine in lung (rabbits, pigs)
ROlHL-23161-01 0004 Biology of myocardial ischemia -
Structure ol myolibrils and membranes in early ischemia
(dogs, rabbit, rodents)
DOSAGE AND ROUTE, RATE AND DURATION OF
ADMINISTRATION
SEE ALSO DRUGS. SLOW RELEASE PREPARATIONS
R23HL-21203-02 Effect of vasoactive agents on leftto-
right shunts (lambs)
ROlHL-2199601 Alteration ol digitalis and aldosterone
disposition (rats, rabbits, mice, dogs)
ROlHL-22065-01 Intractability, medication, and coping
styles in asthma (human)
ROlHL-22567-01 Validation ol a cholesterol absorption
method in man
R23HL-22575-01 Factors modilying cardiac digoxin effects
and content (dogs, cats)
ROlHL-22718-01 Cardiovascular drug interactions-
Metabolism models (dogs)
(contd)
DOS
DOSAGE AND ROUTE, ROUTE OF
ADMINISTRATION
SEE ALSO DRUGS, PHARMACOLOGY, BIOAVAILABILITY
SEE ALSO GASTROINTESTINAL FUNCTION, ABSORPTION-
TRANSPORT. DRUGS
SEE ALSO NUTRITION, DIET SCHEDULE AND ROUTE
** NOlHB-72916-02 Crisis and pain symptom prophylaxis by
oral zinc therapy (human)
R01HL-10834-D9 Fetal and neonatal pulmonary circulation
(goats)
POlHL-12373-10 0013 Cardiopulmonary physiology and
pathophysiology ■ Ettects of cardiovascular drugs on left
ventricular function (dogs)
ROlHL-14127-16 IVIethemoglobinemia and antihypertensive
drugs (cats, mice, rats)
P60HL-15169-05 0018 Support for center for sickle cell
disease ■ Studies on sickle cell disease (human, rats,
dogs)
P50HL17651-04 0016 Ischemic heart disease specialized
center of research - Retroperfusion of coronary venus
circulation with therapeutic agents (dogs)
P50HL-1766504 0011 Study of ischemic heart disease -
Development of new methods for the determination of
infarct size (dog, human)
** R01HL18068-02 Chemistry and activity of homologous
heparin fractions (rodents)
R01HL-1809604 Vasoactive agents in splanchnic viscera
(primates, dogs)
P50HL-19156-02 0003 Pulmonary SCOR-Chronic diseases
of airways ■ Powdered tantalum to study airway morphology
and mucociliary clearance (human)
ROlHL-2001603 Chelator development for thalassemia
(human, mice, rats, dogs, monkeys)
ROlHL-21476-02 Anticoagulant drug absorption
interactions (rats)
R01HL-2199601 Alteration of digitalis and aldosterone
disposition (rats, rabbits, mice, dogs)
** R01HL-22273-01 Oral and lung absorption of nitroglycerin
(rats)
R01HL-2256701 Validation of a cholesterol absorption
method in man
ROlHL-22603-01 Trace metals, vascular activity and
hypertension (rats)
ROlHL-22862-01 CNS-mediated effects of antiarrhythmic
drugs (dogs)
ROlHL-23726-01 Treatment of ventricular arrhythmias with
propranolol (human)
DOSAGE FORMS
SEE ALSO DRUGS, PHARMACOLOGY, BIOAVAILABILITY
SEE ALSO DRUGS, SLOW RELEASE PREPARATIONS
P01HL12738-10 0001 Physiologic pharmacology and its
clinical applications - Clinical pharmacology of cardioactive
drugs (human)
DOSAGE SCHEDULE
SEE DOSAGE AND ROUTE, DOSAGE
DOUBLE RADIOTRACER
SEE RADIOTRACERS, DOUBLE (MULTIPLE)*
DOUBLY RADIOISOTOPE LABELED
SEE RADIOTRACERS, DOUBLE (MULTIPLE)*
DOXAPRAM
SEE 0XA2INES, MORPHOLINES. DOXAPRAM
DOXORUBICIN
SEE ANTIBIOTICS. ADRIAMYCIN
DRILLS
SEE MAMMALS. PRIMATES, MONKEYS AND APES
(ANTHROPOIDS, NON-HUMAN), OLD WORLD MONKEYS
(CATARRHINES)*
DRINKING BEHAVIOR (ALCOHOL)
SEE ALCOHOLISM - DRINKING, ALCOHOL CONSUMPTION
DRINKING BEHAVIOR (WATER)
SEE NUTRIENT INTAKE ACTIVITY, DRINKING BEHAVIOR
(WATER)
DRINKING REGULATORY CENTERS
SEE BRAIN. DRINKING REGULATORY CENTERS
DRIVE
SEE PSYCHOLOGY. MOTIVATION
DROPSY
SEE BODY FLUID BALANCE. EDEMA
DRUG BIOAVAILABILITY
SEE DRUGS. PHARMACOLOGY. BIOAVAILABILITY
DRUG INDUCED NEOPLASMS
SEE NEOPLASMS. DRUG INDUCED
DRUG INFORMATION SYSTEMS
SEE CHEMICAL AND DRUG INFORMATION SYSTEMS
DRUG METABOLISM
SEE DRUGS, PHARMACOLOGY. BIOCHEMICAL
DRUG QUALITY-STANDARDS
P60HL-17269-04 0022 National heart and blood vessel
research and demonstration center - Medicinal chemistry
(rabbit, dog, guinea pig)
184
DRUG REGISTRIES, REFERRAL CENTERS AND
RESOURCES
SEE CHEMICAL AND DRUG REGISTRIES. REFERRAL CENTERS
AND RESOURCES
DRUGS
SEE ALSO ANTIBIOTICS
SEE ALSO ANTIMETABOLITES
SEE ALSO BILE. CHOLAGOGUES AND CHOLERETICS
SEE ALSO BLOOD AND RE DRUGS (GENERAL)
SEE ALSO BLOOD COAGULATION. ANTICOAGULANTS
SEE ALSO BLOOD COAGULATION. ANTIFIBRINOLYTIC AGENTS
SEE ALSO BLOOD COAGULATION. FIBRINOLYTIC AGENTS
SEE ALSO BLOOD COAGULATION. HEMOSTATICS
SEE ALSO BLOOD SUBSTITUTES
SEE ALSO BODY FLUID BALANCE, ACID-BASE, ANTIACIDOSIS
DRUGS
SEE ALSO CALCIFICATION INHIBITORS (CALCIUM NEGATIVE
BALANCE DRUGS)
SEE ALSO CARBOHYDRATE BALANCE. HYPOGLYCEMIC AGENTS
SEE ALSO CARDIOVASCULAR AGENTS
SEE ALSO CARDIOVASCULAR AGENTS. ANTIATHEROGENIC
AGENTS
SEE ALSO CHOLESTANE SERIES. CHOLESTEROL INHIBITORS
SEE ALSO COMMUNICABLE DISEASE CONTROL AGENTS
SEE ALSO CONNECTIVE TISSUE DISORDERS. RHEUMATIC
DISORDERS. ANTIRHEUMATIC AGENTS
SEE ALSO DISEASES. PATHOLOGIC PROCESSES.
INFUMMATION. ANTIINFLAMMATORY AGENTS
SEE ALSO DOSAGE FORMS
SEE ALSO FERTILITY. ANTIFERTILITY DRUGS
SEE ALSO HEMOPROTEINS. HEMOGLOBINOPATHIES. SICKLING
INHIBITORS
SEE ALSO HYPERSENSITIVITY. ANTIALLERGY DRUGS
SEE ALSO IMMUNITY. IMMUNOSUPPRESSIVE AGENTS
SEE ALSO KIDNEY FUNCTION. ANTIDIURETICS
SEE ALSO KIDNEY FUNCTION. DIURETICS
SEE ALSO LIPID MOBILIZING FACTORS
SEE ALSO LIPOGENIC INHIBITORS
SEE ALSO LIPOTROPIC FACTORS
SEE ALSO MEDICINAL CHEMISTRY STUDY SECTION
SEE ALSO MUSCLE REUXANTS
SEE ALSO MUSCLE STIMULANTS
SEE ALSO NATURAL PRODUCTS
SEE ALSO NEOPLASTIC THERAPY. ANTINEOPUSTIC AGENTS
SEE ALSO NEUROPHARMACOLOGICAL AGENTS
SEE ALSO NUTRIENT INTAKE ACTIVITY, APPETITE
DEPRESSANTS
SEE ALSO PLANTS EXTRACTS, MEDICINAL PLANTS
SEE ALSO PROTEOLYTIC AGENTS (NONENZYMATIC)
SEE ALSO PURINES-PYRIMIDINES METABOLISM ERRORS,
GOUT DRUGS
SEE ALSO RESPIRATORY DRUGS, BRONCHOCONSTRICTORS
SEE ALSO RESPIRATORY DRUGS, BRONCHODILATORS
SEE ALSO RESPIRATORY DRUGS, EXPECTORANTS AND
MUCOLYTICS
SEE ALSO TEMPERATURE, CRYOPROTECTIVE AGENTS
SEE ALSO THYROID ANTAGONISTS
** R01HL-018 13-25 Regulation of metabolism by drugs and
hormones (rats)
POlHL-06314-17 0052 Immunologic mechanisms in
cardiovascular disease - Role of cyclic nucleotides in
neutrophil function (human)
ROIHL- 159 80-06 Reactions of hemeproteins and oxygen
(cattle)
** POlHL-174 19-04 0006 Studies on mechanisms of
hemostasis - Effect of hormones, drugs and other agents
on fibrinogen synthesis (chick)
R01HL-17706-04 Psychosocial hypertension,
catecholamines and drugs (mice)
R01HL-22562-02 Mechanism of cardiac action potential
propagation (tunicates)
DRUGS, BLOOD(PLASMA) LEVEL
SEE DRUGS, PHARMACOLOGY, BIOAVAILABILITY
DRUGS, CHEMOTHERAPY
SEE ALSO BILIARY TRACT DISORDERS CHEMOTHERAPY
SEE ALSO BLOOD AND RE DISORDERS CHEMOTHERAPY
SEE ALSO CARDIOVASCUUR DISORDERS CHEMOTHERAPY
SEE ALSO COMMUNICABLE DISEASES CHEMOTHERAPY
SEE ALSO CONNECTIVE TISSUE DISORDERS CHEMOTHERAPY
SEE ALSO DOSAGE AND ROUTE. RATE AND DURATION OF
ADMINISTRATION
SEE ALSO DRUGS. PHARMACOLOGY
SEE ALSO DRUGS, PHARMACOLOGY, BIOAVAILABILITY
SEE ALSO ENDOCRINOLOGY, ENDOCRINE DISORDERS
CHEMOTHERAPY
SEE ALSO ENZYME THERAPY
SEE ALSO EYE DISORDERS CHEMOTHERAPY
SEE ALSO GASTROINTESTINAL DISORDERS CHEMOTHERAPY
SEE ALSO HEART DISORDERS CHEMOTHERAPY
SEE ALSO IMMUNOPATHOLOGY, CHEMOTHERAPY
SEE ALSO IRON CHELATION THERAPY
SEE ALSO KIDNEY DISORDERS CHEMOTHERAPY
SEE ALSO LIVER DISORDERS CHEMOTHERAPY
SEE ALSO METABOLIC DISORDERS CHEMOTHERAPY
SEE ALSO MUSCULAR DISORDERS CHEMOTHERAPY
SEE ALSO NEOPLASTIC THERAPY, CANCER CHEMOTHERAPY
SEE ALSO NERVOUS DISORDERS CHEMOTHERAPY
SEE ALSO NEUROMOTOR DISORDERS CHEMOTHERAPY
SEE ALSO NUTRITIONAL DISORDERS CHEMOTHERAPY
SEE ALSO PREGNANCY, EMBRYO-FETUS CHEMOTHERAPY
DRU
SEE ALSO PREGNANCY DISORDERS CHEMOTHERAPY
SEE ALSO PSYCHOLOGY ABNORMAL, MENTAL DISORDERS
CHEMOTHERAPY
SEE ALSO REPRODUCTIVE SYSTEM DISORDERS
CHEMOTHERAPY
SEE ALSO RESPIRATORY DISORDERS CHEMOTHERAPY
P50HL-2 1006-02 0002 Specialized center of research in
arteriosclerosis - Turnover and metabolism of cholesterol in
man
R01HL-21010-02 Glycemia, other traits and CV death in
40,000 persons
DRUGS, CHEMOTHERAPY, DRUGS
COMBINATION
ROlHL-04666-19 Artificially paced hearts-Technology,
physiology (human, dogs)
POlHL-06370-17 0014 Cardiopulmonary and renal
pathology research center - Quantitative morphology in
cardiac disease (human, rats, dogs)
POlHL-06664-17 0034 Cardiopulmonary function in
remediable vascular disease - Role of hyperosmolar agents
in ischemic heart disease (dogs)
POlHL-06835-17 0030 Cardiovascular disease - Synthesis
and pharmacology of angiotensin antagonists (rats, cats)
POlHL-06835-17 0045 Cardiovascular disease - Pressure-
volume-renin relationship in human hypertension
POlHL-07896-15 0056 Environmental biomedical research
program - Neuromuscular blocking effects of
nondepolarizing muscular relaxants (frogs)
** POlHL-07896-15 0057 Environmental biomedical research
program - Effects of dipyridamole and aspirin on
decompression thrombocytopenia (human)
ROlHL-10711-12 Cooperative study of treatment of
hypertension (human)
POlHL-12738-10 0111 Physiologic pharmacology and its
clinical applications - Cardiovascular pharmacology (dogs)
POlHL-12738-10 0133 Physiologic pharmacology and its
clinical applications - Pharmacologic antagonism of beta-
adrenergic blockade (dogs)
P01HL-13108 09 0001 Clinical heart transplantation -
Therapy and prognosis (human)
POl ML- 13 108-09 0016 Clinical heart transplantation -
Total lymphoid irradiation for immune response (dogs)
ROlHL-13754-08 Postoperative thromboembolism in
surgical patients (human)
P50HL-14197-07 0006 Support for center of research on
arteriosclerosis - Diets and drugs affecting lipid
metabolism (human)
P50HL-14237-07 0006 Support for arteriosclerosis center
- Drug treatment of familial hyperbetalipoproteinemia
(human)
ROlHL-15047-06 Digital computer analysis of the
electrocardiogram (human)
ROlHL-15512-06 Drug treatment of stenosing primate
atherosclerosis (rabbits, monkeys)
ROlHL-15698-12 Factors affecting the action of
anticoagulants (rats, human)
ROlHL-15837-06 Renin and cardiac hypertrophy in
hypertension (rats)
ROlHL-16076-06 Electrophysiology of fibrillation and
defibrillation (human)
POlHL-17417-05 0004 Experimental lung transplantation
- Methods for suppressing lung allograft rejection (dogs,
mice)
P50HL-17655-04 0001 Study of ischemic heart disease ■
Intravenous nitroglycerin-Ventricular function and infarct
size (human, dog)
ROlHL-17736-04 Metabolic change during cardiac
ischemia (rats, dogs)
ROlHL-17776-04 Pulmonary mucus transport in
obstructive lung diseases (human)
ROlHL-17909-04 Drug treatment of vascular scleroproteln
defects (human, turkeys)
P50HL-18323-04 0043 SCOR hypertension center -
Pharmacology-Renin-aldosterone mechanisms in essential
hypertension (human)
P50HL-19170-02 0007 Harvard pulmonary SCOR-Chronic
diseases of the airways - Therapy effect on airway
obstruction in acute asthma (human)
POlHL-19717-02 0040 Response of the lung to injury -
Immunosuppressive drugs in usual interstitial pneumonia
(human)
ROlHL-19818-02 Endocarditis on prosthetic heart valves
(rabbits, human)
R01HL-19937-02 Vasodilators in experimental myocardial
infarction (dogs)
ROlHL-20016-03 Chelator development for thalassemia
(human, mice, rats, dogs, monkeys)
POlHL-20552-02 0002 The development and regression of
cardiac hypertrophy - Effect of treatment on the
hypertrophied left ventricle (rats)
ROlHL-20604-03 Sympathectomy-Cardiovascular and
molecular pharmacology (animals)
ROlHL-20685-02 Pituitary-adrencrgic-ovarian vasomotor
interaction (dogs)
ROlHL-20963-01 Experimental lung abscess (rabbits)
POlHL-20993-02 0005 Population dynamics of arterial
cells in atherogenesis - Drugs other than hypolipidemic
drugs affecting atherosclerosis (swine, rabbits)
R01HL-22040-01 Regulation of lysyl-cross-linking in
vascular tissue (rats, turkeys)
R23HL-22895-01 Smoke inhalation-Biochemical and
cellular responses (rabbits, bacteria)
(contd)
4
•Excludes routine methodology OR covers only general projects which preclude
"Onented significantly to above subject.
indexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
DRU
ORUOS, CHEMOTHERAPY, SELF MEDICATION
R2!>Hl 18406 03 Adheitnca lo hypgrlnnslve medical
r*gimtn] (humin)
R2SHI 18414 03 Hypvittnslon Ftmily sltatt|ies lot
patlfnt idhirance
R25HL 18418 03 Role ol t suppodini paitnei in
•dheitnce (human)
R2SHL 18424 03 Blood pressuie education in an industhil
setlini (human)
ROIHL 19946 03 Reduction ol iron overload in
thalassemia (childien. rabbits, doss, monkeys)
NOIHR 729/2 01 Sell management lor asthmatic children
DRUGS, GASTROINTESTINAL ABSORPTION
SEE GASTROINTESTINAL FUNCTION. ABSORPTION TRANSPORT
DRUGS
DRUGS, PHARMACOLOGY
SEE ALSO BILIARY TRACT PHARMACOLOGY
SEE ALSO BLOOD AND RE SYSTEM PHARMACOLOGY
SEE ALSO CARDIOVASCULAR PHARMACOLOGY
SEE ALSO CHEMICAL STRUCTURE BIOLOGICAL ACTIVITY
SEE ALSO CONNECTIVE TISSUE PHARMACOLOGY
SEE ALSO DRUGS. CHEMOTHERAPY
SEE ALSO DRUGS AND PHYSICAL AND/OR CHEMICAL AGENTS
INTERACTION
SEE ALSO ENDOCRINE PHARMACOLOGY
SEE ALSO GASTROINTESTINAL PHARMACOLOGY
SEE ALSO GENETICS. PHARMACOGENETICS*
SEE ALSO IMMUNOPHARMACOLOGY
SEE ALSO KIDNEY PHARMACOLOGY
SEE ALSO LIVER PHARMACOLOGY
SEE ALSO MUSCLE PHARMACOLOGY
SEE ALSO NEUROPHARMACOLOGY
SEE ALSO PHARMACOLOGY STUDY SECTION
SEE ALSO PHYSICAL AND/OR CHEMICAL AGENTS
INTERACTION (BIOLOGICAL AND ECOLOGICAL)
SEE ALSO PREGNANCY, EMBRYO-FETUS PHARMACOLOGY
SEE ALSO PSYCHOPHARMACOLOGY
SEE ALSO RADIOPHARMACOLOGY
SEE ALSO REPRODUCTIVE SYSTEM PHARMACOLOGY
SEE ALSO RESPIRATORY SYSTEM PHARMACOLOGY
R01HL02063-23 Biochemistry and function of lipids and
cell membranes (human, yeast, animals)
R01HL0394118 Uterine blood flow and changes in
pregnancy (sheep)
P01HL-06664-17 0040 Cardiopulmonary function in
remediable vascular disease • The coupling of ion transport
to metabolism (toads)
R01HL09125-14 Ultrastructural cytochemistry (human,
chick)
ROlHL-12528-10 NMR relaxation of liquid crystal systems
ROIHL- 13349-06 Analysis of activation process in heart
muscle (guinea pigs, rabbits, human)
ROlHL-13587-06 Synthesis of renin inhibitors and analog
phosphatides (rats)
R23HL-19573-01 Studies on pulmonary serotonin (mice)
** ROlHL-20909-02 Clofibrate-enhanced lipid oxidation by
peroxisomes (rats)
POlHL-21016-02 0011 Sickle cell anemia and other
hemoglobinopathies - Metabolic effects of anti-sickling
agents (hamsters)
ROIHL 22137-02 Structure-function pathology of isolated
heart cells (mice, rats)
DRUGS, PHARMACOLOGY, BIOAVAILABILITY
SEE ALSO DOSAGE AND ROUTE, RATE AND DURATION OF
ADMINISTRATION
SEE ALSO GASTROINTESTINAL FUNCTION, ABSORPTION-
TRANSPORT, DRUGS
P60HL-15169-05 0018 Support for center for sickle cell
disease - Studies on sickle cell disease (human, rats,
dogs)
R01HL18003-05 Digitalis-Mechanism and reversal studies
(dog, sheep, duck, guinea pig, human)
POIHL-19242-02 0008 Study of vascular smooth muscle -
NE release in and reactivity of vascular smooth muscle
(rats)
ROlHL-19898-03 Desferrioxamine therapy in thalassemia
(dogs, rats, children)
ROlHL-21052-01 Evaluation of a digitalis therapy advisor
** ROlHL-21105-02 Organ specific drugs-Cardiovascular and
renal effects (dogs)
** R23HL-21151-02 Ischemic myocardium-Delivery of blood
flow and drugs (dogs)
R01HL-2122I-02 Clinical antiarrhythmic and
pharmacodynamic studies
R01HL-2I476-02 Anticoagulant drug absorption
interactions (rats)
ROlHL-22273-01 Oral and lung absorption of nitroglycerin
Microprocessors in medical applications
(rats)
ROlHL-22417-01
(dogs)
R23HL-22575-01 Factors modifying cardiac digoxin effects
and content (dogs, cats)
ROlHL-22718-01 Cardiovascular drug interactions-
Metabolism models (dogs)
R23HL-22882-01 Modulation by disease of effect of
furosemide in man
ROlHL-23726-01 Treatment of ventricular arrhythmias with
propranolol (human)
185
DRUGS, PHARMACOLOGY, BIOCHEMICAL
Sff AISOCHIMK'.AI SIHUCIllRf IIIOIOCICAI ACIIVItY
SEE ALSO DRUGS RECEPIORS
" R0IHl0b806 18 Anilysii ol inliirrhylhmic i|inli (dofi.
rabbits)
" P01HL0e28S 18 0186 Cardiovascular respiratory
physiology and biochemistry Leukocyte hoimone receptors
and cyclic nucleotides (tissue culture)
POIHI 06312 i; 0030 Surgicil cardiology Total
artilicial heart (calves)
POIHL 06350 17 0019 Hemostasis research program
proiecl Microcirculation (human, rats, rabbits)
P01HL0683S 17 0030 Cardiovascular disease Synthesis
and pharmacology ol angiotensin antagonists (rats, cats)
•* POIHL 0683S 17 0031 Cardiovascular disease Synthesis
of potent antagonist ol pressor action ol angiotensin II
(animals)
POIHL 06835 17 0032 Cardiovascular disease Synthesis
of angiotensin II as inhibitors for aldosterone
** POIHL 06835 17 0033 Cardiovascular disease Structure-
activity relationship of angiotensin II analogs (rats)
** P01HL06835 17 0037 Cardiovascular disease Cardiac
hypertrophy in spontaneously hypertensive rat
" P01HL06835 17 0038 Cardiovascular disease Ellect of
chronic administration of angiotensin antagonist (rats)
** POIHL 06835 17 0055 Cardiovascular disease Vascular
and adrenocortical response to angiotensin II (dogs)
** POlHL-06835-17 0056 Cardiovascular disease
Angiotensin analogs-Sarcosine on arterial pressure,
aldosterone (dogs)
POlHl-06835-17 0057 Cardiovascular disease Studies
on cardiac hypertrophy
ROlHL-0750213 Phytochemistry ol the genus thalictrum
(dogs, plants)
POlHL-08899-14 0062 Tolerance to respiratory gases in
health and disease Influence of oxygen at high pressure
upon oxidation (rats)
ROIHL 10608-12 Digoxin-specific antibodies (human)
ROlHL-11154-12 Blood group antigens and antibodies
(human)
POlHL-1 13 10-12 0092 Mechanisms of cardiovascular
disease • Exercise electrophysiology (human)
POlHL-1 13 10-12 0102 Mechanisms of cardiovascular
disease - Cardiac membrane and ion mobility (dogs)
" POlHL-1 13 10-12 0103 Mechanisms of cardiovascular
disease - Heparin-Metabolism and function
** POlHL-12373-10 0012 Cardiopulmonaiy physiology and
pathophysiology - Biochemistry of the sympathetic nervous
system (rats, rabbits, pigeons)
POlHL-12373-10 0013 Cardiopulmonary physiology and
pathophysiology - Effects of cardiovascular drugs on left
ventricular function (dogs)
POlHL-12373-10 0018 Cardiopulmonary physiology and
pathophysiology - Biochemistry laboratory
** ROlHL-12647-08 Inacfivation of norepinephrine in vascular
tissue
ROlHL-12648-09 Catecholamine metabolism in
hypertensive diseases (human)
** POlHL-12738-10 0001 Physiologic pharmacology and its
clinical applications - Clinical pharmacology of cardioactive
drugs (human)
POlHL-12738-10 0065
clinical applications
Physiologic pharmacology and its
Psychotheropeutic drugs and
cardiovascular system (human, rats)
POlHL-12738-10 0107 Physiologic pharmacology and Its
clinical applications - Blood superfused cardiac fibers
(dogs)
POlHL-12738-10 0110
clinical applications
arrhythmias (dogs)
POlHL-12738-10 0129
clinical applications
Physiologic pharmacology and its
Physiology and pharmacology of
Physiologic pharmacology and its
Receptor specificities and
metabolism of vasopressin analogs
ROlHL-12740-10 Hypocholesterolemic agents-
Stereochemistry (rats)
ROlHL-12990-09 Control of antidiuretic hormone secretion
and metabolism (dogs. rats, rabbits)
ROlHL-13257-09 Inhalation anesthesia on myocardial
metabolism (dogs, swine, human)
ROlHL-133 15-08 Disposition of vasoactive hormones in
mammalian lung (rats, rabbits, human)
ROlHL-136 19-09 Microsomal electron transport in liver
and heart (human, mammals)
ROlHL-13636-08 Effects of pharmacologic agents on heart
metabolism (human, rodents)
ROlHL-13666-06 Pharmacology of genesis of cardiac
rhythmicity (rats, cats)
ROlHL-13870-09 Control of myocardial sarcotubular
calcium stores (dogs)
ROlHL-13989-05 Role of water in respiratiory protein
structure
P50HL-14217-08 0058 Specialized center of research in
thrombosis - Mechanisms of induction and inhibition of
platelet reaction (human, pig)
POlHL-14388-07 0190 Regulation of the circulation in
pathological states - Mechanisms of the renal actions of
aldosterone (rats)
ROlHL-14397-07 Hypertension-Angiotcnsin and
prostaglandin pharmacology (animals)
ROlHL-14775-08 Mechanisms of drug action in vascular
smooth muscle (dog, rabbits)
The cardiac histamine receptor (rabbrtt,
Investigation ol hemoglobin S properties
Red cell storage and transfusion
ORU
ROIHl 14847 07 Mtchaniim of action ol vitamin K and
anlicoagulanli (lali)
ROIHl 14992 0/ Mechaniim ol thrombin action (human)
' ROIHl 15002 0/ Bioiheniical pharmacology of luanylala
cyclata in lung (callla. rati)
' P60HI 1515/07 0011 Comprahtniiva cantar for ticUa
cell diieate Davalopment ol ipecilic anii tickling
compound (human)
' P60HL 15160 0/ 0008 Center lor iickle call diiaau
Isocyanate derivatives and hemoglobin S aiiociation
(human, rat)
P60HL 15162 07 0020 Comprehensive sickia call canter
Biophysical studies ol normal and sickle red cells (human)
P60HL 15170 05 0017 Support lor center lor tickle cell
anemia Control ol hemoglobulin synthesis (human)
ROIHL 15698 12 Factors affecting the action ol
anticoagulants (rats, human)
ROIHL 1598506 Metabolic and hormonal control ol
cardiac contraction
ROIHL 16240 05
guinea pigs)
ROIHL 1637504
(human)
ROIHL 16931 04
(human, animals)
ROIHL 16955-05 Heparin, blood coagulation and lipid
metabolism (human)
P60HL 17269 04 0022 National heart and blood vessel
research and demonstration center Medicinal chemistry
(rabbit, dog, guinea pig)
ROIHL 17341-03 Practical total synthesis of
prostaglandins
ROIHL 1755505 Distribution and metabolism ol labeled
digitaloids (dogs, guinea pigs)
P50HL 17670-04 0011 Study of ischemic heart disease -
Pharmacology of ischemic myocardium (dogs)
ROIHL 17796-04 Importance of aminosugars in digitalis
activity (cats, rabbits)
ROlHL-18068-02 Chemistry and activity of homologous
heparin fractions (rodents)
ROIHL 18185-04 Cardiac glycosides and diuretics-Role of
NaO pump (dogs)
ROIHL 18259-03 Controlled intratissue release of
prostaglandins
ROlHL-1888703 Hypolipidemic drugs-Effects on FFA-
albumin association (human, cattle)
POlHL-19259-03 0004 Oigoxin-specilic antibody in human
therapy - Digitalis-specific antibodies pharmacological
studies (human, dogs, sheep)
ROlHL-19772-02 Role of warlarin metabolism in
antivitamin K activity (rats)
ROlHL-20622-02 Pulmonary uptake and accumulation of
drugs (rabbits, rats)
ROlHL-20787-02 Thromboxanes and prostaglandins-
Biochemical pharmacology (rabbits, human)
ROlHL-20859-02 Beta adrenergic catecholamine receptor
P60HL-20985-01 0006 Northern California sickle cell
center - Antisickling properties of imidoesters (human, rats)
POlHL-21016-02 0008 Sickle cell anemia and other
hemoglobinopathies - The clinical variations of sickle cell
anemia
** POlHL-21016-02 0010
hemoglobinopathies
agents
ROlHL-21052-01
** R23HL-21083-02
in humans (rats)
R23HL-21 129-02
" ROlHL-21221-02
Sickle cell anemia and other
Alkylureas as potential anti-sickling
Evaluation of a digitalis therapy advisor
Pharmacokinetics of digoxin and digitoxin
The antisickling effects of imidoesters
Clinical antiarrhythmic and
pharmacodynamic studies
R23HL-21327-02 Molecular mechanisms of chemical
myocardiopathies (rats)
ROlHL-21817-01 Catecholamines, blood pressure and
circulation
ROlHL-2 1996-01 Alteration of digitalis and aldosterone
disposition (rats, rabbits, mice, dogs)
R01HL-22035-01 Molecular modification of heparin by
chemical means (sheep)
ROlHL-22039-02 Ion transport in cardiac muscle (dogs,
rodents, cattle)
ROlHL-222 19-01 Prostacyclin and peroxides in blood and
membrane disease
ROlHL-22258-01 New aspects of pharmacology related to
carbonic anhydrase
ROlHL-22273-01 Oral and lung absorption of nitroglycerin
Cardiovascular pharmacodynamics in
•Excludes routine methodotogy OR covers only general projects which preclude indexing
"Oriented significantly to above subject.
at the specific level.
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number
(rats)
R23HL-22309-01
immature dogs
RO1HL-22566-0I Mesoionic purinones as
phosphodiesterase inhibitors
ROlHL-22685-01 Drugs and excitation-contraction coupling
in heart (animals)
ROlHL-22718-01 Cardiovascular drug interactions-
Metabolism models (dogs)
R01HL-22780-01 Factors modifying the reaction properties
of HgS (human)
R23HL-22882-01 Modulation by disease of effect of
furosemide in man
ROlHL-22896-01 Immediate metabolic fates of kinins and
angiotensins (rat. rabbit, guinea pig)
ROlHL-23586-06 Pharmacologic control of hypersensitivity
phenomena (human)
(contd)
DRU
ROlHL-23726-01 Treatment of ventricular arrhythmias with
propranolol (human)
ROlHL-23980-01 Eftects of digoxin therapy in newborn
and adult sheep
DRUGS, PHARMACOLOGY, STIMULATION,
CHEMICAL
POlHL-08805-15 0046 Regulation of ventilation and
pulmonary circulation ■ Sites and modes of interaction of
peripheral and central chemoreceptors
POlHL-12738-10 0111 Physiologic pharmacology and its
clinical applications - Cardiovascular pharmacology (dogs)
ROlHL-18371-03 Pulmonary hypertension and ventilation
pathophysiology (dogs)
** R01HL18731-02 RES stimulating materials in
experimental shock (dogs)
** R23HL-21369-02 Tracheal mucin synthesis in experimental
bronchitis (rats)
R23HL-21990-01 Accuracy of the ventilatory response to
exercise (dogs)
ROlHL-22426-01 Initiation of the heartbeat-A voltage-
clamp study (bullfrogs, rabbits)
DRUGS, SLOW RELEASE PREPARATIONS
SEE ALSO DRUGS, PHARMACOLOGY, BIOAVAILABILITY
R01HL19898-03 Desfcrrioxamine therapy in thalassemia
(dogs, rats, children)
R01HL1996103 Management of hemosiderosis in
thalassemia (children, adults)
** ROlHL-22888-01 Prosthetic valve endocarditis-Etiology
and therapy (dogs)
DRUGS ABUSE
SEE ALSO PSYCHOLOGY, HABITS, SMOKING
ROlHL-00340-29 Electrolyte disturbance in cardio-renal
disease (human, dogs, rats)
DRUGS ABUSE, OVERDOSE
POIHL 08805-15 0047 Regulation of ventilation and
pulmonary circulation - Extracranial metabolic control of
ventilation (dogs, goats)
ROlHL-20558-02 Cardiac electrophysiology -Effects of ions
and drugs
DRUGS ADVERSE EFFECTS
SEE ALSO DISEASES, COMPLICATIONS, ANESTHESIA RELATED
SEE ALSO DOSAGE AND ROUTE, RATE AND DURATION OF
ADMINISTRATION
SEE ALSO DRUGS, PHARMACOLOGY, BIOAVAILABILITY
SEE ALSO DRUGS HYPERSENSITIVITY
SEE ALSO NEOPLASMS, DRUG INDUCED
SEE ALSO PREGNANCY, EMBRYO FETUS DRUGS ADVERSE
EFFECTS
ROlHL-02965-22 Metabolism of plasma lipoproteins (rats.
chickens, human)
ROlHL-03181-21 0025 Hemodynamics as applied to
surgical problems - Vascular stenosis (dogs)
ROlHL-04512-19 Ultrastructural studies of capillary
permeability (rats, mice)
POlHL-06370-17 0014 Cardiopulmonary and renal
pathology research center - Quantitative morphology in
cardiac disease (human, rats, dogs)
ROlHL-08508-15 Cardiac conductivity and automaticity
(human, dogs, rabbits)
ROlHL-09914-13 The myocardium in diabetes mellitus
(dogs, monkeys)
ROlHL-10582-12 Thrombosis and hemostasis-Analysis,
methods and standards (human, cattle, venom)
** R01HL-10608-12 Digoxin-specific antibodies (human)
** R01HL12557-09 Effects of steroids and pregnancy on
arteries and veins (guinea pigs)
POlHL-12738-10 0001 Physiologic pharmacology and its
clinical applications - Clinical pharmacology of cardioactive
drugs (human)
POlHL-12738-10 0035 Physiologic pharmacology and its
clinical applications - Function and dysfunction of the
sinoatrial node (human)
** POlHL-12738-10 0065 Physiologic pharmacology and its
clinical applications - Psychotheropeutic drugs and
cardiovascular system (human, rats)
P01HL12738-10 0076 Physiologic pharmacology and its
clinical applications - Pediatric cardiac electrophysiology
and pharmacology (human, dogs)
POlHL-12738-10 0107 Physiologic pharmacology and its
clinical applications Blood superfused cardiac fibers
(dogs)
ROlHL-13306-08 Pharmacological control of cardiac
membrane currents (cattle, rabbits)
ROlHL-13315-08 Disposition of vasoactive hormones in
mammalian lung (rats, rabbits, human)
R01HL13666-06 Pharmacology of genesis of cardiac
rhythmicity (rats, cats)
" ROlHL-14127-16 Methemoglobinemia and antihypertensive
drugs (cats, mice, rats)
P50HL- 14236-05 0010 Prevention of premature
arteriosclerosis • Computer programs
P50HL-14237-07 0006 Support for arteriosclerosis center
- Drug treatment of familial hyperbetalipoproteinemia
(human)
POlHL-14388-07 0234 Regulation of the circulation in
pathological states Effects of antiarrhythmic drugs on the
autonomic system (dogs)
186
P60HL-15169-05 0018 Support for center for sickle cell
disease - Studies on sickle cell disease (human, rats,
dogs)
POlHL-15194-07 0004 Pathophysiology of
cardiopulmonary dysfunction - Specialized electrophysiology
fibers -Electrogenic basis of glycosides (mammals)
ROIHL 15526-05 Respiratory mechanics in children
POlHL-15832-06 0011 Chemical-structural predispositions
to lung injury - Interaction of cell receptors with vasoactive
agents in pulmonary vascular bed
P60HL15999-05 0008 Miami comprehensive sickle cell
center - Cyanate effect on host defense -Cellular and
humoral (human, guinea pig. rabbits)
** ROIHL 16052-05 Cardiac glycosides-Mechanism of
inotropic action (dogs)
ROlHL-16076-06 Electrophysiology of fibrillation and
defibrillation (human)
ROlHL-16587-04 Cholesterol binding saponins and
atherosclerosis (monkeys)
ROlHL-17366-05 Mechanisms in the production of renal
hypertension (rabbits, dogs)
ROlHL-17451-05 Digitalis effects on cardiac automaticity
mechanisms
** ROlHL-17555-05 Distribution and metabolism of labeled
digitaloids (dogs, guinea pigs)
ROlHL-17724 03 Oral contraceptives and hypertension
(rats)
ROlHL-17993-04 0003 Ventricular dynamics from
surgically inserted markers - Effects of pharmacologic
agents on left ventricular dynamics (human)
** ROlHL-18003-05 Digitalis-Mechanism and reversal studies
(dog, sheep, duck, guinea pig. human)
ROlHL-18096-04 Vasoactive agents in splanchnic viscera
(primates, dogs)
ROlHL-18163-04 Red cell membrane effects due to
oxidizing agents
ROlHL-181 75-03 Drug taking for hypertension in a rural
community
ROlHL-18598-03 Role of Na, K-ATPase inhibition on
digitalis action
POlHL-18646-03 0001 Studies basic to heart
transplantation - Individualized regulation of
immunosuppression (dogs, rats)
** ROlHL-18923-02 Steroid-induced hyperlipidemia and
hypertension (human, rats)
ROlHL-19045-03 Electrophysiology of cardiac automaticity
(human, dogs)
ROlHL-19055-03 Platelet function during extracorporeal
perfusion (human, mammals)
ROlHL-19255-03 Evaluation of diagnostic clinical
hemorrheology (human)
M POlHL-19259-03 Digoxin-specific antibody in human
therapy
" POlHL-19259-03 0001 Digoxin-specific antibody in human
therapy - Primary structure of monoclonal antibodies
(rabbits)
** POlHL-19259-03 0004 Digoxin-specific antibody in human
therapy - Digitalis-specific antibodies pharmacological
studies (human, dogs, sheep)
ROlHL-19487-03 Cardiac actions of digitalis (dogs, cats)
POlHL-197 17-02 0008 Response of the lung to injury -
Experimental models of lung disease
ROlHL-19720-03 Evaluation of anti-fibrotic agents in
pulmonary fibrosis (rats)
ROlHL-19898 03 Desferrioxamine therapy in thalassemia
(dogs, rats, children)
ROlHL-20000-03 Iron overload in homozygous beta
thalassemia (human)
ROlHL-202 11-02 Role of taurine in the heart (dogs, rats,
mice)
ROlHL-20558-02 Cardiac electrophysiology-Effects of ions
and drugs
** ROlHL-20572-02 0007 Hemodynamic relations to
metabolism in hypertension - Drug effects on cardiac
function and hypertropy (rats)
ROlHL-20622-02 Pulmonary uptake and accumulation of
drugs (rabbits, rats)
ROlHL-20754-02 Anesthetic-induced myocardial depression
(rabbits)
ROlHL-20856 02 Platelet transfusions-Usage and
complications (human)
ROlHL-21052-01 Evaluation of a digitalis therapy advisor
R23HL-21083-02 Pharmacokinetics of digoxin and digitoxin
III humans (rats)
R23HL-2 11 96-02 Digitalis induced arrhythmia and NAO KO-
atpase activity (dogs)
** R23HL-212 12-02 Alveolar macrophage function in
Fseudomonas infection (dgs)
ROlHL-21221-02 Clinical antiarrhythmic and
pharmacodynamic studies
ROlHL-21308-01 Prostaglandins and local control of the
circulation (rats, dogs)
R23HL-21327-02 Molecular mechanisms of chemical
myocardiopathies (rats)
ROlHL-21533-02 Platelet inhibitor drug in coronary surgery
(human)
ROlHL-21540-02 Specific inhibitors of coagulation and
fibrinolysis (rats, rabbits, dogs)
R23HL 21973-01 Catecholamine metabolism and the heart
(human, guinea pigs)
ROlHL-21996-01 Alteration of digitalis and aldosterone
disposition (rats, rabbits, mice, dogs)
DRU
** R23HL-21997-01 Pulmonary immunopathology in the
compromised host (guinea pigs)
ROlHL-22201-01 Pharmacology and chemistry of
nudibranch toxins (guinea pigs, rats, mice)
ROlHL-22273-01 Oral and lung absorption of nitroglycerin
(rats)
POlHL-22619-01 0003 Cellular mechanisms of heart
failure - Digitalis induced inotropy in myocardial ischemia
heart failure (animals)
POlHL-22619-01 0010 Cellular mechanisms of heart
failure - Mitochondria in heart and smooth muscle (rabbits,
rats, dogs)
ROlHL-22748-01 Effect of bile sequestration on VLDL
metabolism (human)
ROlHL-22750-01 Digoxin in heart failure with sinus
rhythm (human)
ROlHL-23603-01 Morphogenesis of hypertensive vascular
disease (rats)
NO IHV- 12434- 11 Therapy for hypertension in the general
population
NOlHV-12436-15 Hypertension therapy in the general
population (human)
NOlHV-12442-14 Therapy for hypertension in the general
population (human)
NOlHV-22931-14 Therapy for hypertension In general
population
NOlHV-22937-07 Therapy for hypertension in general
population
NOlHV-22938-11 Therapy for hypertension in general
population
** NOlHV-62900-00 Study of breast cancer and reserpine use
(human)
NOlHV-72931-02 Non-invasive detection of athenjsclerotic
lesions (human, dogs)
NOlHV-82915-01 Therapy for hypertension in the general
population (human)
DRUGS ADVERSE EFFECTS EMBRYO-FETAl
SEE PREGNANCY, EMBRYO-FETUS DRUGS ADVERSE EFFECTS
DRUGS AND PHYSICAL AND/OR CHEMICAL
AGENTS INTERACTION
SEE ALSO DRUGS INTERACTION
** POlHL-11310-12 0103 Mechanisms of cardiovascular
disease - Heparin-Meta holism and function
"* ROIHL 16549-04 Cardiotonic steroid-NaK ATPase
interactions (cattle)
ROlHL-20996-02 Structural and reactivity of iron and
cobalt complexes
NOIHV 72943-01 Prostaglandin and kallikrein kinin system
antagonists
NOlHV-72944-02 Prostaglandin and kallikrein kinin
antagonists
NOlHV-72945-03 Develop prostaglandin synthesis and
receptor antagonists
NOlHV-72946-02 Development of kalllkrein-Klnin system
antagonists
DRUGS COMBINATION
SEE DRUGS, CHEMOTHERAPY. DRUGS COMBINATION
DRUGS DEPENDENCY
SEE DRUGS ABUSE
DRUGS HYPERSENSITIVITY
** P50HL-14153-07 0012 Johns Hopkins Lung Center-
Chronic diseases of airways - Aspirin intolerance in
reversible lung disease (human)
ROlHL-15190-07 Physiological basis of arrhythmias and
their therapy (human)
ROlHL-16611-04 Digitalis-receptor of the heart (guinea
pigs, rats)
POlHL-19737-02 0003 Cellular and molecular aspects of
respiratory physiology - Cortisol-dependent alterations in
lung type II cells (rats)
** ROlHL-20184-02 Desensitization of tracheal muscle to
isoproterenol (rats, rabbits)
DRUGS INTERACTION
SEE ALSO DRUGS, CHEMOTHERAPY. DRUGS COMBINATION
SEE ALSO DRUGS AND PHYSICAL AND/OR CHEMICAL AGENTS
INTERACTION
ROlHL-05883-18 0001 Reflex control of resistance and
capacitance vessels - Naturally occurring vasoactive
substances and the vascular neuroeffectors (dog)
POlHL-06285-18 0182 Cardiovascular-respiratory
physiology and biochemistry - Structure and function of
vascular chemoreceptors (cats, rats)
POlHL-06314-17 0066 Immunologic mechanisms in
cardiovascular disease - Sensitization, cell-mediated
cytotoxicity, role of lymphocytes (human, mice)
POlHL-06835-17 0030 Cardiovascular disease - Synthesis
and pharmacology of angiotensin antagonists (rats, cats)
" POlHL-06835-17 0031 Cardiovascular disease - Synthesis
of potent antagonist of pressor action of angiotensin II
(animals)
POlHL-06835-17 0033 Cardiovascular disease - Structure-
activity relationship of angiotensin II analogs (rats)
POlHL-06835-17 0055 Cardiovascular disease - Vascular
and adrenocortical response to angiotensin II (dogs)
POlHL-07896-15 0056 Environmental biomedical research
program - Neuromuscular blocking effects of
nondepolarizing muscular relaxants (frogs)
(contd)
•Excludes routine methodology OR covers only general projects which preclude
"Ofiented significantly to above subject.
indexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix (or investigator's name and grant number.
DRU
POIHl 10436 IJ OOM A mullidisclpllni(Y study ol
conianitil htirl dliuso CtrdlovascuUi phaimacology
(do|)
POIHl 173/3 10 0012 Caidiopulmonaiy physiology and
pathophysioloiy Biochemistry ot Iho sympathetic noivaus
syslam (tats, labbits. piicons)
** POIHL 12738 10 006S Physiologic pharmacology and Us
clinical applications Psychothtiupeudc diugs and
cardiovasculai system (human, lats)
ROIML 13636 08 Ellocts ot phaimacologic agents on heart
metabolism (human, rodents)
PSOHL 14217 08 0061 Specialiied cantei ol losoarch In
thrombosis Pharmacology Comparison ol platelets and
vascular smooth muscle (animal)
ROIHL I477!i08 Mechanisms ol drug action in vascular
smooth muscle (dog, rabbits)
ROIHL 14832 06 Myocardial cells Autonomic and rhythmrc
mechanisms (chick embryo, rats)
ROIHL 14847 07 Mechanism ol action ol vitamin K and
anticoagulants (rats)
R01HL'1S698 12 Factors atlecting the action ot
anticoagulants (rats, human)
** R01HL157S8 06 Catecholamine release in the heart
(dogs)
ROIHL 1605205 Cardiac glycosides Mechanism of
inotropic action (dogs)
ROIHL'1607606 Eleclrophysiology ot fibrillation and
defibrillation (human)
POIHL 1741904 0006 Studies on mechanisms of
hemostasis Effect of hormones, drugs and other agents
on fibrinogen synthesis (chick)
R01HL1786504 Studies on aging Effects ol sex
hormones (rats, dogs)
ROIHL- 1790904 Drug treatment of vascular scleroprotein
defects (human, turkeys)
ROlHL'18175-03 Drug taking for hypertension in a rural
community
R01HL1879504 Ischemic arrhythmias-Effect of
autonomic tone (dogs, rats, guinea pigs)
ROlHL-20199-02 Drug-induced alterations in infarct size
in the rat
ROlHL-20622-02 Pulmonary uptake and accumulation of
drugs (rabbits, rats)
ROlHL-20685-02 Pituitary-adFenergic-ovarian vasomotor
interaction (dogs)
ROlHL-20783-02 Airway reactivity~B-adrenoceptors and
prostaglandins (guinea pigs)
R01HL-2I30801 Prostaglandins and local control of the
circulation (rats, dogs)
** ROlHL-21476-02 Anticoagulant drug absorption
interactions (rats)
ROIHL 21996 01 Alteration of digitalis and aldosterone
disposition (rats, rabbits, mice, dogs)
" ROlHL-22718-01 Cardiovascular drug interactions-
Metabolism models (dogs)
DRUGS OVERDOSE
SEE DRUGS ABUSE, OVERDOSE
DRUGS RECEPTORS
SEE ALSO ENDOCRINOLOGY, HORMONE RECEPTORS
R01HL-05806-18 Analysis of antiarrhythmic agents (dogs,
rabbits)
POlHL-06835-17 0055 Cardiovascular disease - Vascular
and adrenocortical response to angiotensin II (dogs)
POlHL-0683517 0056 Cardiovascular disease -
Angiotensin analogs-Sarcosine on arterial pressure,
aldosterone (dogs)
R01HL-10608-12 Digoxin-specific antibodies (human)
** POlHL-12738-10 0129 Physiologic pharmacology and its
clinical applications - Receptor specificities and
metabolism of vasopressin analogs
ROlHL-13306-08 Pharmacological control of cardiac
membrane currents (cattle, rabbits)
ROlHL-13339-08 Pharmacology of developing cardiac
tissues (chick embryo)
ROlHL-13427-09 Neural control of blood volume (monkeys,
dogs)
ROlHL-13909 27 Physiochemistry and immunology of
macromolecules
P50HL-142 17-08 0061 Specialized center of research in
thrombosis - Pharmacology-Comparison of platelets and
vascular smooth muscle (animal)
P60HL-15157-07 0011 Comprehensive center for sickle
cell disease - Development of specific anti-sickling
compound (human)
P60HL-15162-07 0020 Comprehensive sickle cell center
Biophysical studies of normal and sickle red cells (human)
** POIHL 15832-06 0011 Chemical-structural predispositions
to lung injury - Interaction of cell receptors with vasoactive
agents in pulmonaiy vascular bed
R01HL-i6052-05 Cardiac glycosides -Mechanism of
inotropic action (dogs)
'* ROIHL- 16240-05 The cardiac histamine receptor (rabbits,
guinea pigs)
ROIHL- 16549-04 Cardiotonic steroid-NaK ATPase
interactions (cattle)
ROlHL-16611-04 Digitalis-receptor of the heart (guinea
pigs, rats)
** ROlHL-17879-04 Molecular structure of the ouabain
sensitive ATPase (dogs)
ROlHL-18003-05 Digitalis-Mechanism and reversal studies
(dog, sheep, duck, guinea pig, human)
187
ROIHI 18015 03 Phaimicoloflc itudiM on vascular
Miiuolh iniisria (dOfi, rill)
KOIIII I8U5 04 Cardiac ilytotldti and diurtlics Rol* ol
NaU ptimp (dogs)
KOIHI 18936 02 Heart preseivation and transplantation
studios (lat)
POIHL 19242 02 0008 Study ol vascular smooth muscle
Nf release in and reactivity ol vascular smooth muscle
dais)
ROIHL 19995 02 Sensory transduction in cjidiac
mechanuieceptors (cats. Irogs, rats)
ROIHL 20262 02 Cardiac glycosides and the mechanism
ol the sodium potassium pump
ROIHL 20787 02 Ihromboxanes and prostaglandins-
Biochemical pharmacology (rabbits, human)
" POIHl 20984 02 0005 Cellular mechanisms in cardiac
hypertrophy Neurohumoral receptors in cardiac growth
and compensatory hypertrophy (animals)
ROIHL 21457 01 C(17)side group geometry and
cardenolide activity (cats, guinea pigs)
ROIHL 21996 01 Alteration of digitalis and aldosterone
disposition (rats, rabbits, mice, dogs)
ROIHL 2203902 Ion transport in cardiac muscle (dogs,
rodents, cattle)
** ROIHL 22079-01 Heart receptor sites lor digitalis and
steroid hormones (animals)
ROlHl-22174 01 Assembly ol membranes in heart and
yeast mitochondria
ROIHL 2223901 The molecular basis of electrical
excitability (chick embryos, rats)
R23HL-22245-02 Functional characteristics of atrial
receptors (rats)
DRUGS RESISTANCE
POIHL 06308 18 0029 Mechanisms and therapy of
circulatory disease Characterization of the patient with
recurrent ventricular arrhythmias
DRUGS RESISTANCE, MICROBIAL
SEE ALSO GENETICS. MICROBIAL
R01HL19818-02 Endocarditis on prosthetic heart valves
(rabbits, human)
ROIHL 20963-01 Experimental lung abscess (rabbits)
DRUGS SCREENING
POlHL-06664-17 0036 Cardiopulmonary function in
remediable vascular disease - In vitro studies on the
mechanism of Ischemic damage to cells (rabbits)
ROlHL-07502-13 Phytochemistry of the genus thalictrum
(dogs, plants)
ROiHL-12740-10 Hypocholesterolemic agents-
Stereochemistry (rats)
*• R01HL-I2971-15 Reactions of alkoloids and their analogs
ROlHL-14847-07 Mechanism of action of vitamin K and
anticoagulants (rats)
P60HL-15157-07 0011 Comprehensive center for sickle
cell disease - Development of specific anti-sickiing
compound (human)
P60HL 15160-07 0008 Center for sickle cell disease -
Isocyanate derivatives and hemoglobin S association
(human, rat)
P60HL-15160-07 0011 Center for sickle cell disease -
Study of human sickle cells in an animal model (rats)
** ROlHL-15512-06 Drug treatment of stenosing primate
atherosclerosis (rabbits, monkeys)
ROlHL-17796-04 Importance of aminosugars in digitalis
activity (cats, rabbits)
ROlHL-17909-04 Drug treatment of vascular scleroprotein
defects (human, turkeys)
POlHL-18576-03 0012 Thrombosis research program
project - Synthetic anticoagulant and thrombolytic agents
(dogs)
** ROIHL-19066-03 Synthesis and evaluation of
prostaglandin metabolites (guinea pigs)
ROlHL-19378-03 Relation of mitochondrial changes to
cardiac failure (dogs, rats)
" ROlHL-200 16-03 Chelator development for thalassemia
(human, mice, rats, dogs, monkeys)
POlHL-20993-02 0005 Population dynamics of arterial
cells in atherogenesis - Drugs other than hypolipidemic
drugs affecting atherosclerosis (swine, rabbits)
" ROlHL-21457-01 C(17)-side group geometry and
cardenolide activity (cats, guinea pigs)
ROiHL-22098-01 Is postoperative infarction due to
reperfusion injury? (human, dogs)
ROlHL-222 19-01 Prostacyclin and peroxides in blood and
membrane disease
ROlHL-22566-Or Mesoionic purinones as
phosphodiesterase inhibitors
POlHL-226 19-01 9002 Cellular mechanisms of heart
failure - Medicinal chemistry and clinical intervention
ROlHL-22862-01 CNS-mediated effects of antiarrhythmic
drugs (dogs)
DRUGS SYNTHESIS AND PRODUCTION
ROlHL-022 12-23 Coagulation of blood (human)
** POlHL-06835-17 0030 Cardiovascular disease - Synthesis
and pharmacology of angiotensin antagonists (rats, cats)
** POlHL-06835-17 0031 Cardiovascular disease - Synthesis
of potent antagonist of pressor action of angiotensin II
(animals)
** POlHL-06835-17 0032 Cardiovascular disease - Synthesis
of angiotensin II as inhibitors for aldosterone
ORU
I'OIHI II3I0 I? 0103 Murhanltmt ol cardiovatculat
diMiase Heiitiin MMaboliim and function
RUIHI IMI8U9 Puly diamu»iplin>pl.i/ani>
POIHl 12/38 lU 0129 Phytiologic phaim<>.oki(y and Hi
clinical applicalloni Receploi -.ppciliriliiii and
metabolism ol vasopressin analogs
ROIHl 12/40 10 Hypoclinle'ileiolamir. agents
Stereochemistry (rail)
ROIHl 12971 15 Reai.lionj ol alkoloids and their analofi
ROIHl 14509 0/ Hypertension Chemistry and bwphytlci
ol angiotensin
P60III 1 5 1 5/ 0/ 00 n Compiehensive center lor sickle
cell disease OevolopmenI ol specilic anti sickling
compound (hurnan)
ROIHL 154/6 05 Mechanism and control ol sterol
biosynthesis (rats)
ROIHL 16796 05 Cholesterol regulation by HMC CoA
reductase (rats, human)
P60HL 17269 04 0022 National heart and blood vessel
research and demonstration center Medicinal chemistry
(rabbit, dog. guinea pig)
ROIHL 17341 03 Practical total synthesis of
prostaglandins
ROIHL 17552 03 Sickling inhibition by chemical
modification of hemoglobin (human)
ROIHL 1773904 Acute myncardial infarct scintigraphy
(human, dogs, rats)
ROIHL 17897-03 Synthesis of alpha and beta adrenergic
antagonists
ROIHL 18015-03 Pharmacologic studies on vascular
smooth muscle (dogs, rats)
ROIKL 1824503 Transition state analog inhibitors of
thrombin (human, cattle)
POlHL-18576 03 0012 Thrombosis research program
project - Synthetic anticoagulant and thrombolytic agents
(dogs)
ROlHL-18679 04 Synthetic protease inhibitors
ROlHL-18744-03 Preparation of radiopharmaceuticals from
drug analogs
ROIHL 18818-04 Stereochemical mechanism of sickling of
hemoglobin S (human)
ROiHL-18993 03 Biological investigations of substance P
ROlHL-1906603 Synthesis and evaluation of
prostaglandin metabolites (guinea pigs)
ROlHL-19127-03
imaging (rats)
ROlHL-19514-03
Synthesis of molecules for myocardial
Proteinase inhibitor model with clinical
Synthesis of potential antihypertensive
potential
ROlHL-19538 03
agents
ROIHL- 19820-02 The chemistry and biological effects of
heparin (Rhesus, human, other mammals)
ROlHL-19898-03 Desferrioxamine therapy in thalassemia
(dogs, rats, children)
ROlHL-200 16-03 Chelator development for thalassemia
(human, mice, rats, dogs, monkeys)
ROtHL-20579-02
alkaloids
ROlHL-21367-02
Synthesis of therapeutically important
Polyether ionophores-Synthesis of X537A
•Excludes routine methodotogy OR covers only general projects which preclude indexing
Oriented significantly to above subject.
at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigators name and grant number.
and analogs
** ROlHL-21457-01 C(17)-side group geometry and
cardenolide activity (cats, guinea pigs)
ROlHL-21670-01 Antiarrhythmic studies on 2-sub3tituted
aminoindenes (dogs)
** ROlHL-22035 01 Molecular modification of heparin by
chemical means (sheep)
ROlHL-22219-01 Prostacyclin and peroxides in blood and
membrane disease
ROlHL-22522-01 Cardioselectivity of beta-adrenoceptor
antagonists
'* ROlHL-22532-01 Inhibitors of cholesterol biosynthesis
(rats, mice, yeast)
ROlHL-22566-01 Mesoionic purinones as
phosphodiesterase inhibitors
ROlHL-22612-01 Stabilized prostacyclins to treat vasculai
disease
POlHL-22619-01 9002 Cellular mechanisms of heart
failure - Medicinal chemistry and clinical intervention
" R01HL-22778-01 Total synthesis of natural cardiotonic
ionophores
ROlHL-23183 01 Voltage dependent conductance in
membranes
DRUGS TACHYPHYLAXIS
SEE ALSO DRUGS TOLERANCE
POlHL-06835-17 0030 Cardiovascular disease - Synthesis
and pharmacology of angiotensin antagonists (rats, cats)
POlHL-12738-10 0065 Physiologic pharmacology and its
clinical applications - Psychotheropeutic drugs and
cardiovascular system (human, rats)
P50HL-14153-07 0014 Johns Hopkins Lung Center-
Chronic diseases of airways - Mediator release in asthma
(human)
** POlHL-19242-02 0008 Study of vascular smooth muscle -
NE release in and reactivity of vascular smooth muscle
(rats)
ROlHL-19653-03 Circulatory system effects ot angiotensin
analogs (rats)
ROlHL-20184-02 Desensitization of tracheal muscle to
isoproterenol (rats, rabbits)
** ROlHL-20685-02 Pituitary-adrenergic-ovarian vasomotor
interaction (dogs)
(contd)
DRU
ROlHL-20783-02 Ainvay reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
DRUGS TOLERANCE
SEE ALSO DRUGS TACHYPHYLAXIS
PO1HL-1A388-07 0168 Regulation of the circulation in
pathological states - Ionic basis of depolarization (rats,
tissue culture)
ROlHL-22273-01 Oral and lung absorption of nitroglycerin
(rats)
DRUGS TOXICOLOGY
SEE DRUGS ADVERSE EFFECTS
DRUGS VEHICLES
SEE ALSO DRUGS, PHARMACOLOGY, BIOAVAILABILITY
R01HL1964703 Therapeutic aerosols
ROlHL-19700-03 Deposition of hygroscopic aerosols
(models)
ROlHL-197 15-02 Respiratory tract deposition of
hygroscopic aerosols (dogs, human)
ROlHL-19722-03 Aerosol growth in the respiratory system
(models)
ROlHL-20024-03 Therapeutic aerosols-Characteristics and
retention (human, dogs)
** ROlHL-22470-01 Liposome myocardial uptake in infarct
and ischemia (dogs, rats, mice)
DRUGS WITHDRAWAL (SYMPTOMS)
** R23HL-21973-01 Catecholamine metabolism and the heart
(human, guinea pigs)
DSR
SEE RADIOGRAPHY, SCANNING, DSR
DT-DIAPHORASE
SEE OXIDOREDUCTASES, NAD(P)H DEHYDROGENASE
(QUINONE)
DUCTUS ARTERIOSUS EMBRYONIC
SEE CARDIOVASCULAR SYSTEM, DUCTUS ARTERIOSUS
EMBRYONIC
DUCTUS ARTERIOSUS PATENT
SEE CONGENITAL ABNORMALITIES, CAROIOVASCUUR SHUNTS
ABNORMAL, PATENT DUCTUS
DUODENAL ULCER
SEE GASTROINTESTINAL DISORDERS, DUODENAL, DUODENAL
ULCER
DURATION OF TREATMENT
SEE DOSAGE AND ROUTE, RATE AND DURATION OF
ADMINISTRATION
DUST
SEE PHYSICAL PROPERTIES, PARTICLES, DUST
DWARF CHIMPANZEE
SEE MAMMALS, PRIMATES, MONKEYS AND APES
(ANTHROPOIDS, NON-HUMAN), GREAT APES (PONGIDS),
PAN (CHIMPANZEE)*
DWARFISM
SEE SKELETAL DISORDERS. BONE OEVELOPMENT. DWARFISM
DYES
SEE ALSO ACRIOINES
SEE ALSO AZO (AZINO) COMPOUNDS
SEE ALSO BENZOFURANONES, PHTHALIDES,
BROMSULPHTHALEIN
SEE ALSO BENZOPYRANS, XANTHENES, FLUORESCEINS
SEE ALSO BENZOPYRROLES, INDOCYANINE GREEN
SEE ALSO CYANINE
SEE ALSO MEROCYANINES
ROlHL-14826-05 External isotope assay of atherosclerosis
(rats, rabbits)
•* ROlHL-17702-04 Electro-optical dyes as probes of heart
excitability
DYES, FLUORESCENT DYES AND PROBES
SEE ALSO IMMUNOLOGICAL TESTS AND IMMUNOASSAY,
IMMUNOFLUORESCENCE*
SEE ALSO RAOIOFLUORESCENT PROBES
ROlHL-15648-06 Lipid metabolism -Transport by lateral
diffusion (human, rabbit, cattle)
** POlHL-16117 05 0004 Ion movements and membranes in
cardiovascular control - Optical studies of excitation-
contraction coupling (frogs, snakes)
POlHL-16683-04 0003 Function and grovrth of cardiac
and skeletal muscle • Movements of S-1 moieties in muscle
fibers
ROlHL-16828-04 Gradient and transport of oxygen in
tissue and organs (mammals)
P01HL17421-05 0001 Regulation and exchange in the
microcirculation - Mass transfer and microcirculatory
function (rats)
•* P01HL17421-05 0007 Regulation and exchange in the
microcirculation - Core facilities-Fluorometric measurement
methods for microcirculation
** ROlHL-20254-02 Probes of heart and nerve membranes -
Fluorescent dyes
ROIHL 22402-01 Heparin-biophysical, chemical and
biological aspects (mice, human)
DYNAMIC SPATIAL RECONSTRUCTOR
SEE RADIOGRAPHY, SCANNING, DSR
188
DYSAUTONOMIA FAMIUAL
SEE CONGENITAL ABNORMALITIES. NEUROLOGICAL.
DYSAUTONOMIA FAMILIAL
DYSBARISM
SEE INJURIES. DYSBARISM
DYSKINESIA
SEE NEUROMOTOR DISORDERS
DYSLIPOPROTEINEMIAS
SEE LIPOPROTEINS BLOOD. DYSLIPOPROTEINEMIAS
DYSPNEA
SEE RESPIRATORY DISORDERS. DYSPNEA
DYSPROTEINEMIAS ACQUIRED
SEE BLOOD PROTEINS DISORDERS
DYSPROTEINEMIAS CONGENITAL
SEE BLOOD PROTEINS DISORDERS CONGENITAL
DYSTROPHIA MYOTONICA
SEE METABOLIC DISORDERS INBORN. MYOTONIA ATROPHICA
EAR, HEARING, AUDITORY THRESHOLD
POlHL-07896-15 0008 Environmental biomedical research
program - Otologic studies under hyperbaric conditions
(human, animals)
EAR, HEARING, COCHLEAR MICROPHONICS
POlHL-07896-15 0008 Environmental biomedical research
program - Otologic studies under hyperbaric conditions
(human, animals)
PClHL-08899-14 0052 Tolerance to respiratory gases in
health and disease - Oxygen effects on auditory and
vestibular function (human, guinea pigs)
EAR, LABYRINTH
POlHL-08899-14 0052 Tolerance to respiratory gases in
health and disease - Oxygen effects on auditory and
vestibular function (human, guinea pigs)
EAR, LABYRINTH, COCHLEA
POlHL-07896-15 0008 Environmental biomedical research
program - Otologic studies under hyperbaric conditions
(human, animals)
EAR, LABYRINTH, VESTIBULAR APPARATUS
POlHL-07896-15 0008 Environmental biomedical research
program - Otologic studies under hyperbaric conditions
(human, animals)
POlHL-0889914 0078 Tolerance to respiratory gases in
health and disease - Isobaric gas counterditfusion -Sensory.
cutaneous and systemic function (animals)
POlHL-08899-14 0085 Tolerance to respiratory gases in
health and disease - Search for gas bubbles in vestibular
fluids (animals)
EAR, LABYRINTH, VESTIBULAR REFLEX
** POlHL-08899-14 0052 Tolerance to respiratory gases in
health and disease - Oxygen effects on auditory and
vestibular function (human, guinea pigs)
** POlHL-14388-07 0184 Regulation of the circulation in
pathological states - Vestibular reflexes in control of
circulation (human)
EAR, LABYRINTHINE FLUIDS
** POlHL-08899-14 0085 Tolerance to respiratory gases in
health and disease - Search for gas bubbles in vestibular
fluids (animals)
EAR, LABYRINTHINE FLUIDS, ENDOLYMPH
POlHL-08899-14 0052 Tolerance to respiratory gases in
health and disease - Oxygen effects on auditory and
vestibular function (human, guinea pigs)
EAR DISORDERS, HEARING DISORDERS
** POlHL-07896-15 0008 Environmental biomedical research
program - Otologic studies under hyperbaric conditions
(human, animals)
EAR DISORDERS, MIDDLE EAR DISORDERS
** POlHL-07896-15 0008 Environmental biomedical research
program - Otologic studies under hyperbaric conditions
(human, animals)
EAR DISORDERS, MIDDLE EAR DISORDERS,
OTITIS MEDIA
ROlHL-14271-07 Physico-chemical properties of tracheal
mucus (dogs, frogs)
EAR DISORDERS DIAGNOSIS, HEARING TESTS,
AUDIOMETRY*
POlHL-08899-14 0052 Tolerance to respiratory gases in
health and disease - Oxygen effects on auditory and
vestibular function (human, guinea pigs)
EARLY CHILDHOOD
SEE CHILDREN, PRESCHOOL (1 TO 6 YRS)
EARLY DIAGNOSIS
SEE DIAGNOSTIC TESTS, EARLY DIAGNOSIS*
EARTH ALKALI GROUP METALS
SEE METALS, ALKALINE EARTH METALS
EDU
EARTHS RARE
SEE METALS, RARE EARTHS
EATING BEHAVIOR
SEE NUTRIENT INTAKE ACTIVITY, FEEDING (EATING)
BEHAVIOR
EATON-LIU AGENT
SEE BACTERIA, MYCOPLASMATALES, MYCOPLASMA
PNEUMONIAE*
EATON'S AGENT PNEUMONIA
SEE RESPIRATORY DISORDERS, PNEUMONIA MYCOPLASMAL
(PPLO)
EB VIRUS
SEE VIRUSES. HERPESVIRUSES. EB VIRUS
ECG GATED CARDIAC BLOOD POOL IMAGING
SEE HEART VISUALIZATION*
ECHOCARDIOGRAPHY
SEE HEART VISUALIZATION. ECHOCARDIOGRAPHY*
ECHOENCEPHALOGRAPHY
SEE BRAIN VISUALIZATION. ULTRASONIC
ECHOENCEPHALOGRAPHY*
ECLAMPSIA
SEE PREGNANCY TOXEMIAS AND HYPERTENSION. ECLAMPSIA
ECOLOGICAL TOXICOLOGY
SEE TOXICOLOGY. ENVIRONMENTAL
ECOLOGY ANIMAL
SEE ENVIRONMENT. ECOLOGY ANIMAL
ECOLOGY HUAAAN
SEE ENVIRONMENT, ECOLOGY HUMAN
ECONOMICS
SEE HEALTH ECONOMICS
SEE SOCIOECONOMICS
EDEMA
SEE BODY FLUID BALANCE, EDEMA
EDEMA QUINCKE'S
SEE METABOLIC DISORDERS INBORN, ANGIONEUROTIC
EDEMA (HEREDITARY)
EDETIC ACID
SEE AMINO ACIDS. ETHYLENEOIAMINO ACIDS. EDTA
EDTA
SEE AMINO ACIDS, ETHYLENEOIAMINO ACIDS, EDTA
EDUCATION, AUDIOVISUAL AND OTHER
TRAINING AIDS
SEE ALSO EDUCATION, COMPUTER ASSISTED INSTRUCTION
SEE ALSO EDUCATION, PROGRAMMED INSTRUCTION
P60HL-15157-07 0003 Comprehensive center for sickle
cell disease - Public education
P60HL-15168-07 0003 Comprehensive sickle cell disease
center - Sickle cell education and training program
P60HL-1 5996-06 0006 Cincinnati comprehensive sickle
cell center - Education
P60HL-16008-06 0011 Wayne State University
comprehensive sickle cell center - Education, screening and
counseling
P60HL-17265-04 0010 Community blood resource center
support - Blood resources educational program
P60HL-17269-04 0036 National heart and blood vessel
research and demonstration center - Public education
P60HL-17292-04 0024 Vermont Lung Center • Education
and media resources unit
P50HL-19190-02 0002 Pulmonary SCOR-Pathophysiology.
management of IRDS - Core-Demonstration and
dissemination
P60HL-20985-01 0011 Northern California sickle cell
center - SNMA community education program
R23HL-22947-01 Experimental systems to improve youth
behavior (smoking prevention)
NOlHR-62934-02 Evaluate continuing education In
pulmonary medicine
EDUCATION, COMPUTER ASSISTED
INSTRUCTION
SEE ALSO EDUCATION, PROGRAMMED INSTRUCTION,
TEACHING MACHINES
P60HL-17265-04 0010 Community blood resource center
support - Blood resources educational program
** P60HL-17292-04 0008 Vermont Lung Center - Respiratory
physiology-Teaching, learning and auditing problem-solving
skills
R18HL-21906-01 Stanford five city multifactor risk
reduction study
EDUCATION, CURRICULUM
P60HL-1 5160-07 0003 Center for sickle cell disease -
Genetic counseling in hemoglobinopathies-Oimensions,
effectiveness
P60HL-15996-06 0006 Cincinnati comprehensive sickle
cell center - Education
** P60HL-17265-04 0010 Community blood resource center
support - Blood resources educational program
(contd)
*Exdudes routine melhodotogy OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number
fOU
** P60HI 1726904 OOJ/ National htait and blood vtiul
rauitch and damonstiation cental Sacondaiy and
unlvtfsity aducatlon
P60HL i;269 04 0047 National titirt and blood vossel
rtitarcb and damonstration center Evaluation ol
competency based educational model
P60HL 17292 04 0018 Vermont lung Cenlei Group
patient education Bieatliing worKshop proiecl
P60HU 7292 04 0020 Vermont Lung Center Mass
intormetion Education project
P60HL 17292 04 0021 Vermont Lung Center School lung
education project
P60HL'1729204 0024 Vermont Lung Center Education
ind media resources unit
P60HL 23282 01 9001 Comprehensive hospital/community
sicKle cell center Core Institutionalization ol education,
screening and counseling
NOIHR 62931 02 Development and evaluation ol
continuing education in pulmonary medicine
EDUCATION, HEALTH EDUCATION
SEE ALSO PSYCHOLOGY. ATIIIUOE TO HEALTH AND HEALTH
PROBLEMS
•" P60HL 15157 07 0001 Comprehensive center (or sickle
cell disease Screening program (human)
P60HL 1515707 0002 Comprehensive center (or sickle
cell disease Central data bank and research tile
** P60HL 15157 07 0003 Comprehensive center tor sickle
cell disease Public education
M P60HL15158 07 Comprehensive sickle cell center
** P60HL 1515807 0009 Comprehensive sickle cell center -
Counseling and social services
P60HL-1515807 0012 Comprehensive sickle cell center •
Clinical services-'Pediatric patients
** P60HL-1515807 0028 Comprehensive sickle cell center -
Education
** P60HL 15160-07 0003 Center tor sickle cell disease
Genetic counseling in hemoglobinopathies-Dimensions.
eHectiveness
•* P60HL-1516007 0017 Center for sickle cell disease -
Demonstration -Education, screening, counseling, patient
care
"* P60HL-1516207 0010 Comprehensive sickle cell center ■
Core program -Community outreach and education program
P60HL-1516207 0011 Comprehensive sickle cell center ■
Core program -Genetic counseling and diagnostic screening
P60HL-15168-07 0002 Comprehensive sickle cell disease
center - Patient care
*• P60HL15168-07 0003 Comprehensive sickle cell disease
center • Sickle cell education and training program
** P60HL15168-07 0010 Comprehensive sickle cell disease
center ■ Sickle cell center project (children)
** P60HL-15169-05 0017 Support for center for sickle cell
disease - Study of the natural history of sickle cell disease
in the home
P60HL-15169-05 0019 Support for center for sickle cell
disease ■ Central screening and reference laboratory
** P60HL-15169-05 0021 Support for center for sickle cell
disease - Multidisciplinary module system for education,
screening and counseling
P60HL-1517005 0002 Support for center for sickle cell
anemia - Adult services -Testing programs
** P60HL-15170-O5 0003 Support (or center for sickle cell
anemia - Adult services-Educational programs
** P60HL-15170-05 0008 Support for center for sickle cell
anemia - Pediatric services -Education program
P60HL-15170-05 0023 Support for center for sickle cell
anemia ■ Comprehensive sickle cell clinic
** P60HL-15170-O5 0030 Support for center for sickle cell
anemia - Adult services-Counseling program
P60HL-15996-05 0004 Cincinnati comprehensive sickle
cell center - School adjustment of sickle cell patients
** P60HL-I5996-06 0005 Cincinnati comprehensive sickle
cell center - Factors precipitating crises (human)
** P60HL-1599606 0006 Cincinnati comprehensive sickle
cell center - Education
P60HL-1599606 0007 Cincinnati comprehensive sickle
cell center - Screening and counseling
P60HL15996-06 0008 Cincinnati comprehensive sickle
cell center - Patient care (children, adults)
P60HL- 15996-06 0009 Cincinnati comprehensive sickle
cell center - Insurance coverage of persons with sickle cell
trait and disease
** P60HL-15999-05 0004 Miami comprehensive sickle cell
center - Education, screening and counseling
P60HL-1599905 0005 Miami comprehensive sickle cell
center - Sickle cell clinic
** P60HL-16005-05 0001 Comprehensive sickle cell center ■
Demonstration-Community service component
P60HL-16005-05 9001 Comprehensive sickle cell center -
Core laboratory and counseling (human)
** P60HL- 16008-06 0001 Wayne State University
comprehensive sickle cell center - Patient care system
(children, adults)
** P60HL-16008-06 0011 Wayne State University
comprehensive sickle cell center - Education, screening and
counseling
** P60HL- 17265-04 0001 Community blood resource center
support • Demonstration and evaluation
M P60HL-1 7292-04 Vermont Lung Center
** P60HL-17292-04 0018 Vermont Lung Center • Group
patient education-Breathing workshop project
Ma\%
189
** P60HI 17292 04 0020 Vermont lung Cenlci
inloriTialion iducalion project
" I'bOHL I7?9;U4 00?! Vermont Lung Center School lung
eduiatiuM project
•• P60HL 1/292 04 0024 Vmmorit lung Center [duration
and media resources unit
M P60H1 20985 01 Northern Calilornia sit kle cell center
•• P60HI 20985 01 0008 Northern Calitornio sickle cell
center Demonstration community program Patient
ambudsman
" P60HL 20985 01 0009 Northern California sickle cell
center Patient services (children, adults)
•• P60HL 20985 01 0011 Northern CaMornia sickle cell
center SNMA community education program
** R23HL 22947 01 Experimental systems to improve youth
behavior (smoking prevention)
M P60HL 23282 01 Comprehensive hospital/community sickle
cell center
** P60HL 2328201 9001 Comprehensive hospital/community
sickle cell center Core Institutionalization o( educadon.
screening and counseling
P60HL 2328201 9002 Comprehensive hospital/community
sickle cell center Core Model sickle cell service for
neighborhood health centers
•* NOIHR 72973 01 Health education and attitudes of family
toward asthmatic children
NOIHR 72974 01 Self management systems (or asthmatic
children
NOIHV 7298300 Nutrition counseling in hyperlipidemia
EDUCATION, HEALTH EDUCATION,
CARDIOVASCULAR DISEASE EDUCATION
SEE ALSO NATIONAL HIGH BLOOD PRESSURE EDUCATION
RESEARCH PROGRAM COMMITTEE
** R25HL17056-01 Improving patient compliance through
nursing action
P60HL- 1726904 National heart and blood vessel research
and demonstration center
P60HL17269-04 0036 National heart and blood vessel
research and demonstration center - Public education
P60HL-17269-04 0037 National heart and blood vessel
research and demonstration center - Secondary and
university education
P60HL1 7269-04 0038 National heart and blood vessel
research and demonstration center - Continuing education
P60HL-17269-04 0039 National heart and blood vessel
research and demonstration center - Health care services
to patients in neighborhood clinics
P60HL-17269-04 0042 National heart and blood vessel
research and demonstration center - Social-psychological
smoking deterrents in schools
P60HL- 172 69-04 0043 National heart and blood vessel
research and demonstration center - Dietary modification-
Effect on cardiovascular risk parameters (human)
P60HL-17269-04 0047 National heart and blood vessel
research and demonstration center - Evaluation of
competency-based educational model
ROlHL-181 75-03 Drug taking for hypertension In a rural
community
ROlHL-18235-03 Cardiovascular fitness and other risk
factors (human)
P50HL- 183 23-04 0035 SCOR hypertension center ■ Control
of high blood pressure at the work site
R25HL-18406-03 Adherence to hypertensive medical
regimens (human)
R25HL-184 14-03 Hypertension-Family strategies for
patient adherence
R25HL-184 18-03 Role of a supporting partner in
adherence (human)
M
R25HL-18424-03
setting (human)
ROlHL-18715-02
ROlHL-20244-02
ROlHL-20245-01
ROlHL-20247-01
ROlHL-20248-01
ROlHL-20910-02
prevention (human)
ROlHL-21427-02
patients
ROlHL-21578-01
adolescent
R18HL-21906-01
reduction study
ROlHL-222 12-01
control program
R23HL-22345-02 0001
compliance strategies
patterns (human)
R23HL-22345-02 0002
compliance strategies
Blood pressure education in an Industrial
Hypertension incidence project (human)
he impact of hypertension information
The impact of hypertension information
The impact of hypertension information
The impact of hypertension information
The alternative diet for coronary disease
I)
Behavioral changes in post infarction
Effect of exercise upon the hypertensive
Stanford five city multifactor risk
Alameda county high blood pressure
Behavioral cardiovascular
Long term modification of dietary
Behavioral cardiovascular
Compliance with antihypertensive
medication regimens (human)
ROlHL-22380-01 Detroit hypertension control program
ROlHL-22802-01 A rural mining community hypertension
control project (human)
R18HL-22934-01
hypertension
N01HV12434-11
Behavorial approaches to adolescent
Therapy for hypertension in the general
population
NOlHV-12435-15 Therapy for hypertension in the general
population (human)
NOlHV-12436-15 Hypertension therapy in the general
population (human)
EDU
NOIHV 12440 14 Ihaiapy (or hyparleniion in Ihr lennal
population (human)
NOIHV 12442 14 Therapy (or hyperltniion in the (tneral
population (human)
NOIHV 22931 14
population
NOIHV 2293/0/
Therapy lor hyperlaniion in gantril
therapy (or hypertansHin in general
Therapy (or hypertantion in general
Hypertension detecdon and lollmi up
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
•*Orient<K) significantly to al»ve subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
population
NOIHV 22938 II
population
NOIHV 22939 12
program center
NOIHV 22945 11 Cooperative hypertension detection and
follow up study (human)
** NOIHV 82913 00 Demonstration programs in hypertension
control in the work setting (human)
NOIHV 82915 01 Therapy (or hypertension in the genera(
population (human)
EDUCATION, HEALTH OCCUPATIONS
P60HL 1515/ 0/ 0003 Comprehensive center lor sickle
cell disease Public education
P60HL 15160 07 0017 Center (or sickle cell disease
Demonstration Education, screening, counseling, patient
care
P60HL 151620/ 0010 Comprehensive sickle cell center
Core program Community outreach and education program
** P60HL 151680/ 0003 Comprehensive sickle cell disease
center Sickle cell education and training program
P60HL 15996 06 0006 Cincinnati comprehensive sickle
cell center Education
P60HL 15999 05 0004 Miami comprehensive sickle cell
center - Education, screening and counseling
P60HL 15999-05 0005 Miami comprehensive sickle cell
center Sickle cell clinic
P60HL-1600806 0011 Wayne Slate University
comprehensive sickle cell center Education, screening and
counseling
** P60HL-17265 04 0010 Community blood resource center
support Blood resources educational program
M P60HL-17269 04 National heart and blood vessel research
and demonstration center
P60HL-17292-04 0013 Vermont Lung Center Regional
management of respiratory disease program
P60HL 17292-04 0024 Vermont Lung Center Education
and media resources unit
** P60HL-1 7292-04 0030 Vermont Lung Center Hospital
treatment of pneumonia
P60HL- 17292-04 0031 Vermont Lung Center - Regional
respiratory computer network
R23HL-22345-02 0001 Behavioral cardiovascular
compliance strategies - Long term modification of dietary
patterns (human)
NOlHV-62941-01 Nutrition coding center for MRFIT and
LRC programs
EDUCATION, HEALTH OCCUPATIONS, ALLIED
P60HL-15157-07 0003 Comprehensive center for sickle
cell disease - Public education
P60HL-15158-07 0028 Comprehensive sickle cell center -
Education
P60HL-15160-07 0003 Center for sickle cell disease •
Genetic counseling in hemoglobinopathies-Dimensions.
effectiveness
P60HL-15168-07 0003 Comprehensive sickle cell disease
center - Sickle cell education and training program
P60HL151 70-05 0003 Support for center for sickle cell
anemia - Adult services-Educational programs
P60HL-15996-06 0007 Cincinnati comprehensive sickle
cell center • Screening and counseling
P60HL-16005-05 0001 Comprehensive sickle cell center -
Demonstration -Community service component
P60HL- 1726904 0037 National heart and blood vessel
research and demonstration center ■ Secondary and
university education
P60HL1 726904 0038 National heart and blood vessel
research and demonstration center - Continuing education
P60HL-23282-01 9002 Comprehensive hospital/community
sickle cell center - Core -Model sickle cell service for
neighborhood health centers
EDUCATION, HEALTH OCCUPATIONS,
CONTINUING EDUCATION
P60HL-15158-07 0028 Comprehensive sickle cell center -
Education
P60HL-15162-07 0011 Comprehensive sickle cell center -
Core program-Genetic counseling and diagnostic screening
P60HL-15168-07 0005 Comprehensive sickle cell disease
center - Ophthalmology (human, rabbits, monkeys)
P60HL-15996-06 0008 Cincinnati comprehensive sickle
cell center - Patient care (children, adults)
P60HL-17265-04 0001 Community blood resource center
support - Demonstration and evaluation
" P60HL- 17269-04 0038 National heart and blood vessel
research and demonstration center - Continuing education
** P60HL-1/269-04 0047 National heart and blood vessel
research and demonstration center - Evaluation of
competency-based educational model
" P50HL-19190-02 0002 Pulmonary SCOR-Pathophysiology.
management of IRDS - Core-Demonstration and
dissemination
R18HL-21906-01 Stanford five city multifactor risk
reduction study
(contd)
EDU
** NOlHR-62931-02 Development and evaluation of
continuing education in pulmonary medicine
** NOlHR-62934-02 Evaluate continuing education in
pulmonary medicine
EDUCATION, HEALTH OCCUPATIONS, MEDICAL
" ROlHL-0869615 0018 Orthotopic heart transplantation -
Training in cardiac transplantation
P60HL-15158-07 0028 Comprehensive sickle cell center •
Education
P60HL-1516007 0003 Center for sickle cell disease -
Genetic counseling in hemoglobinopathies -Dimensions,
effectiveness
P60HL15168-07 0003 Comprehensive sickle cell disease
center - Sickle cell education and training program
P60HL-1517005 0003 Support for center for sickle cell
anemia ■ Adult services -Educational programs
P60HL-15170-05 0008 Support for center for sickle cell
anemia - Pediatric services-Education program
P60HL-17269 04 0038 National heart and blood vessel
research and demonstration center ■ Continuing education
** P60HL-1 7269-04 0047 National heart and blood vessel
research and demonstration center - Evaluation of
competency-based educational model
** P60HL 17292-04 0008 Vermont Lung Center • Respiratory
physiology -Teaching, learning and auditing problem-solving
skills
P50HL-19190-02 0002 Pulmonary SCOR-Pathophysiology,
management of IRDS - Core -Demonstration and
dissemination
P60HL-20985-01 0011 Northern California sickle cell
center - SNMA community education program
R23HL-2234502 0001 Behavioral cardiovascular
compliance strategies - Long term modification of dietary
patterns (human)
R23HL-22345-02 0002
compliance strategies
Behavioral cardiovascular
Compliance with antihypertensive
medication regimens (hum^n)
P60HL-2328201 9002 Comprehensive hospital/community
sickle cell center - Core Model sickle cell service for
neighborhood health centers
** NOlHR-62931-02 Development and evaluation of
continuing education in pulmonary medicine
** NOlHR-6293402 Evaluate continuing education in
pulmonary medicine
** N01HV-62969-03 Cardiology patient simulator evaluation
EDUCATION, HEALTH OCCUPATIONS, NURSING
P60HL15157-07 0003 Comprehensive center for sickle
cell disease - Public education
P60HL15158-07 0028 Comprehensive sickle cell center ■
Education
P60HL-15168-07 0003 Comprehensive sickle cell disease
center ■ Sickle cell education and training program
P60HL-15170-05 0008 Support for center for sickle cell
anemia - Pediatric services -Education program
R25HL17056-01 Improving patient compliance through
nursing action
P50HL-19190-02 0002 Pulmonary SCOR-Pathophysiology,
management of IRDS ■ Core -Demonstration and
dissemination
P60HL-20985-01 0011 Northern California sickle cell
center - SNIVIA community educationprogram
EDUCATION, POSTGRADUATE
ROlHL-05694-20 Functional pathology of cardiovascular
disease (human)
P60HL-15168-07 0003 Comprehensive sickle cell disease
center • Sickle cell education and training program
P60HL15I70-05 0008 Support for center for sickle cell
anemia - Pediatric services-Education program
P60HL-1729204 0008 Vermont Lung Center - Respiratory
physiology- Teaching, learning and auditing problem-solving
skills
EDUCATION, PROGRAAAAAED INSTRUCTION
P60HL17269-04 0037 National heart and blood vessel
research and demonstration center - Secondary and
university education
P60HL17269-04 0038 National heart and blood vessel
research and demonstration center - Continuing education
NOlHR-62931-02 Development and evaluation of
continuing education in pulmonary medicine
EDUCATION, PROGRAMAAED INSTRUCTION,
TEACHING MACHINES
NOlHV-62969-03 Cardiology patient simulator evaluation
EDUCATION, SCHOOLS
" P60HL- 15996-06 0004 Cincinnati comprehensive sickle
cell center - School adjustment of sickle cell patients
P60HL- 15996-06 0006 Cincinnat* comprehensive sickle
cell center - Education
** P60HL- 17269-04 0042 National heart and blood vessel
research and demonstration center • Social-psychological
smoking deterrents in schools
P60HL-1729204 0021 Vermont Lung Center • School lung
education project
NOlHR-7297401 Self-management systems for asthmatic
children
190
EDUCATION, SCHOOLS, SECONDARY
P60HL-17269 04 0037 National heart and blood vessel
research and demonstration center - Secondary and
university education
R23HL-22947-01 Experimental systems to improve youth
behavior (smoking prevention)
EDUCATION, SPECIAL (REMEDIAL)
SEE ALSO HEALTH CARE SERVICES, REHABILITATION
VOCATIONAL
SEE ALSO MENTAL HEALTH SERVICES, REHABILITATION
PSYCHOSOCIAL
** P60HL-15158-07 0010 Comprehensi
Tutorial service for sickle cell anemia patients
P60HL-15169-05 0021 Support for center for sickle cell
disease - Multidisciplinary module system for education,
screening and counseling
P60HL-1599606 0008 Cincinnati comprehensive sickle
cell center • Patient care (children, adults)
P60HL-1600806 0011 V.' yne State University
comprehensive sickle cell center ■ Edi)(fe6bi(f,'%ftj!iifiSS'^nd
counseling
P60HL-20985-01 0008 Northern California sickle cell
center Demonstration community program -Patient
ambudsman
EDUCATION, TEACHING
P60HL-15996-06 0004 Cincinnati comprehensive sickle
cell center • School adjustment of sickle cell patients
P60HL-15996-06 0006 Cincinnati comprehensive sickle
cell center - Education
P60HL-17269-04 0037 National heart and blood vessel
research and demonstration center ■ Secondarv and
university education
EDUCATION, TRAINING
SEE ALSO INFORMATION DISSEMINATION, MEETINGS
CONFERENCES SYMPOSIA, WfORKSHOP
•* R01HL08696-15 0018 Orthotopic heart transplantation -
Training in cardiac transplantation
P50HL-191 70-02 0009 Harvard pulmonary SCOR-Chronic
diseases of the airways - Ventilatory muscle training in
chronic obstructive pulmonary disease (human)
EDUCATION, TRAINING LEVEL
SEE ALSO PSYCHOLOGY, PERFORMANCE, ACADEMIC
ACHIEVEMENT
ROlHL-21010-02 Glycemia, other traits and CV death in
40,000 persons
** ROlHL-230 78-01 Psychosocial stress and sudden coronary
death (human)
EDUCATION, TRAINING LEVEL, EDUCATIONALLY
DISADVANTAGED
P60HL-151 58-07 0010 Comprehensive sickle cell center -
Tutorial service for sickle cell anemia patients
EDUCATION, UNIVERSITIES
P60HL17269-04 0037 National heart and blood vessel
research and demonstration center - Secondary and
university education
EDUCATION PROGRAMS (SYSTEMS)
EVALUATION-PLANNING
P60HL-15157-07 0003 Comprehensive center for sickle
cell disease - Public education
P60HL1516807 0003 Comprehensive sickle cell disease
center • Sickle cell education and training program
** R25HL17056-01 Improving patient compliance through
nursing action
P60HL17265-04 0010 Community blood resource center
support - Blood resources educational program
P60HL 17269-04 0036 National heart and blood vessel
research and demonstration center ■ Public education
P60HL17269-04 0037 National heart and blood vessel
research and demonstration center ■ Secondary and
university education
** P60HL-17269-04 0038 National heart and blood vessel
research and demonstration center - Continuing education
P60HL- 172 69-04 0043 National heart and blood vessel
research and demonstration center - Dietary modification-
Effect on cardiovascular risk parameters (human)
** P60HL- 172 69-04 0047 National heart and blood vessel
research and demonstration center - Evaluation of
competency-based educational model
** P60HL- 172 92-04 0008 Vermont Lung Center ■ Respiratory
physiology-Teaching, learning and auditing problem -solving
skills
P60HL1729204 0018 Vermont Lung Center ■ Group
patient education-Breathing workshop project
P60HL-1729204 0021 Vermont Lung Center - School lung
education project
** P60HL- 172 92-04 0024 Vermont Lung Center - Education
and media resources unit
R25HL18424-03 Blood pressure education in an industrial
setting (human)
P60HL 20985-01 0011 Northern California sickle cell
center ■ SNMA community education program
R18HL-21906-01 Stanford five city multifactor risk
reduction study
** NOlHR-62931-02 Development and evaluation of
continuing education in pulmonary medicine
** NOlHV-62969-03 Cardiology patient simulator evaluation
ELE
EDUCATIONAL LEVEL
SEE EDUCATION, TRAINING LEVEL
EDUCATIONAL PSYCHOLOGY
SEE PSYCHOLOGY EDUCATIONAL (GENERAL)
EDUCATIONALLY DISADVANTAGED
SEE EDUCATION, TRAINING LEVEL, EDUCATIONALLY
DISADVANTAGED
EFFERENT NERVES
SEE NERVOUS SYSTEM, EFFERENT NERVES
EFFORT, PHYSICAL
SEE HEALTH, PHYSICAL ACTIVITY. EXERCISE
EGF
SEE GROWTH FACTORS (INCL. ANABOLICS), EPIDERMAL
GROVffH FACTOR
EGG SHELL
POlHL-14414-07 0004 Environmental influences on
cardiorespiratory and cellular functions • Role of diffusion
ill gas exchange (chicken egg)
EHLERS-DANLOS SYNDROME
SEE METABOLIC DISORDERS INBORN. EHLERS-OANLOS
SYNDROME
EHRLICH TUMOR
SEE NEOPUSMS, CARCINOMA, EHRLICH TUMOR
8,1 1,14-EICOSATRIENOATE, HYDROGEN-
DONOR: OXYGEN OXIDOREDUCTASE
SEE OXIDOREDUCTASES. PROSTAGLANDIN SYNTHASE
EJACULATORY DUCT
SEE REPRODUCTIVE SYSTEM MALE, EPIDIDYMIS AND DUCTS
ELASTASE
SEE PROTEASES AND PEPTIDASES, ELASTASE
ELASTASE INHIBITORS
SEE ENZYME INHIBITORS, ELASTASE INHIBITORS
ELASTIC TISSUE
SEE CONNECTIVE TISSUE. ELASTIC TISSUE
ELASTICITY
SEE PHYSICAL PROPERTIES, ELASTICITY
ELASTIN
SEE ALBUMINOIDS, ELASTIN
ELASTOGRAPHY
SEE PHYSICAL PROPERTIES, ELASTICIH
ELASTOMERS
SEE PLASTICS, ELASTOMERS
ELECTRIC COUNTERSHOCK (DEFIBRILLATION)
SEE HEART RESUSCITATION, ELECTRIC COUNTERSHOCK
ELECTRIC COUNTERSHOCK (HEART
RESUSCITATION)
SEE HEART RESUSCITATION, ELECTRIC COUNTERSHOCK
ELECTRICAL BURNS
SEE INJURIES, BURNS, ELECTRICAL
ELECTRICAL CONDUCTION
SEE ALSO ELECTRICAL IMPEDANCE
SEE ALSO IONIZATION
ROlHL-21632-02 Development of a transcutaneous power
transfer system (cattle)
ELECTRICAL DEFIBRILLATION
SEE HEART RESUSCITATION, ELECTRIC COUNTERSHOCK
ELECTRICAL DOUBLE LAYER POTENTIAL
SEE ELECTROPOTENTIALS, 2ETA POTENTIAL
ELECTRICAL FIELDS
SEE ELECTRICITY-MAGNETISM, ELECTRICAL FIELDS
ELECTRICAL IMPEDANCE
SEE ALSO ELECTRICAL CONDUCTION
** ROlHL-14688-05 Myocardial assessment by inverse
electrocardiography (monkey)
R0iHL18050-04 Mechanisms of cardiovascular
teratogenesis (chick embryo) k embrvo)
R01HL19118-03 Measurement of airways mechanics
(human, dog)
** ROlHL-19678-01 Quantification of intrathoracic fluid by
impedance (human, dogs)
ELECTRICAL MEASUREMENTS (SEE ALSO
SPECIFICS)*
R01HL17702-04 Electro-optical dyes as probes of heart
excitability
ELECTRICAL MEASUREMENTS, OSCILLOGRAPHY
i
i
I
i
R01HL1804004
(calves)
ROlHL-18947-02
(mammals)
R01HL19118-03
(human, dog)
Waveform dependency in defibrillation
Indirect mean arterial pressure
Measurement of airways mechanics
(contd)
I
•Excludes routine methodolo© OR covers only general proiects which preclude
••Oriented significantly to above subject.
indexing at the specific level.
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
■u
191
■U
R01H1228M0I Non invasivt blood pnisurt
mstsurtminl (rits)
ELECTRICAL MEASUREMENTS, POLAROGRAPHY*
RQIHL 11901 12 001/ [Itrcts ol molabolit suigory on
the hyptilipidtmias Mrmbiane p«ini«4bility. blood
viscosity, oxyien uptakt Rli«olo|y studies (ubbils)
ROIHI 19083 02 Rapid spocilir micio me;isui«iiiiiiit ot
blood cholesleiol
ELECTRICAL MEASUREMENTS, POTENTIOMETRY*
ROIHL 193S00? Prevrntlon ot thrombosis by applied
elKttic fields (sheep)
ELECTRICAL POTENTIALS
Sff ElfCIROPOUNIIAlS
ELECTRICITY-MAGNETISM, DIELECTRIC
PROPERTIES
PSOHL 1414708 0014 Specialised center ol leseatch in
thrombosis Theoretical models for electrostatic ellects in
blood clot formation
ELECTRICITY-MAGNETISM, DIPOLE MOMENTS
ROIHL'16901 05 Multipolar linkage between heart
geometry and surface (human, dogs)
** ROIHL 1948603 Oipole moment measurement of cardiac
mass (rabbits, pigs)
ROIHL 7072502 Mechanisms and cellular functions of ion
transport
ROIHL'21283'02 Simulation studies of the ECG in acute
ischemia (and human)
ELECTRICITY -MAGNETISM, ELECTRICAL FIELDS
•* ROIHI 1935002 Prevention ot thrombosis by applied
electric fields (sheep)
ELECTRICITY-MAGNETISM, MAGNETIC FIELDS
ROIHL'12494 10 Continuum mechanics in biophysics
(human, animals)
ROIHL 1398807 Elimination ot reoperative cardiac
pacemaker surgery (dogs)
M ROlHL'l 754303 Magnetic tracers tor diagnosis of lung
disease
** R01HL1754303 0001 Magnetic tracers for diagnosis ot
lung disease - Chronic, interstitial lung disease (human.
rabbits)
** R01HL1754303 0002 Magnetic tracers for diagnosis of
lung disease Magnetite as an index of asbestos exposure
(human)
•• ROlHL-17543-03 0003 Magnetic tracers for diagnosis of
lung disease - Occupationally accumulated magnetite for
diagnosis of lung disease (human)
*' ROlHL-1754303 0004 Magnetic tracers for diagnosis of
lung disease - Magnetite retention, distribution, relaxation
rs.e, viscosity (rabbits)
** R01HL1832103 Fluid shear or magnetic alignment of
blood components (human)
ELECTROCARDIOCORDER
SEE HEART DISORDERS DIAGNOSIS. ELECTROCARDIOGRAPHY
MONITOR. ELECTROCARDIOCORDER*
ELECTROCARDIOGRAPHY
SEE HEART DISORDERS DIAGNOSIS.
ELECTROCARDIOGRAPHY*
ELECTROCARDIOGRAPHY FREQUENCIES
SEE HEART DISORDERS DIAGNOSIS. ELECTROCARDIOGRAPHY
FREQUENCIES*
ELECTROCARDIOGRAPHY MONITOR
SEE HEART DISORDERS DIAGNOSIS. ELECTROCARDIOGRAPHY
MONITOR*
ELECTROCARDIOGRAPHY MONITOR (PORTABLE)
SEE HEART DISORDERS DIAGNOSIS. ELECTROCARDIOGRAPHY
MONITOR, ELECTROCARDIOCORDER*
ELECTROCHEMISTRY
SEE CHEMISTRY. ELECTROCHEMISTRY
ELECTRODES*
ROlHL-22699-01 Defibrillation electrode studies (dogs,
swine)
ELECTRODES, ENZYME*
ROIHL- 19083-02 Rapid specific micro measurement of
blood cholesterol
ELECTRODES, MICROELECTRODES*
P01HL06285-18 0198 Cardiovascular respiratory
physiology and biochemistry - Renal tubular secretion of
hydrogen ion (animals)
** POlHL-20592 02 0003 Cell biology of cardiac and
skeletal muscle - Cellular magnesium and anion activities
in ion-specific microelectrodes (frogs)
ROlHL-23624-01 Effect of drugs on ischemic cardiac cells
(dogs, guinea pigs, pigs)
ELECTRODES, PLATINUM*
ROlHL-22815-01 Region-I myocardial function after
revascularization (dogs)
ELECTRODIFFUSION
SEE BIOLOGICAL TRANSPORT, PASSIVE TRANSPORT.
DIFFUSION
ELECTROENCEPHALOGRAPHIC DETERMINATION
OF DEATH
SI I DIAIII CIKIHKAI
ELECTROENCEPHALOGRAPHY
St! BRAIN mciHICAl ALIIVIIY
ELECTROFOCUSING
SET PHYSICAI SICARAIION Ft ECTROFOCUSINC*
ELECTROGENIC ION PUMP
SEf BIOIOGICAL TRANSPORT. ACTIVE TRANSPORT. ION
PUMPS
ElECTROKINETIC POTENTIAL
SEF EIFCTROPOIFNIIALS, 2EIA POTENTIAL
ELECTROLYSIS, STATIONARY
SEE PHYSICAL SEPARAIION, ElECIROFOCUSING*
ELECTROLYTE EXCHANGE AND TRANSPORT
SEE BIOIOGICAL TRANSPORT, ION EXCHANGE AND
TRANSPORT
ELECTROLYTE-WATER BALANCE
SEE BODY FLUID BAUNCE. IONIC
ELECTROLYTES
SEE IONS. ELECTROLYTES
ELECTROMAGNETIC BLOOD FLOWMETERS
SEE CARDIOVASCULAR DISORDERS DIAGNOSIS. BLOOD FLOW
MEASUREMENTS, ELECTROMAGNETIC*
ELECTROMAGNETIC FIELDS
SEE ELECTRICITY MAGNETISM, MAGNETIC FIELDS
ELECTROMAGNETIC FIELDS (HEART)
SEE HEART DISORDERS DIAGNOSIS, VECTOR
MAGNETOCARDIOGRAPHY*
ELECTROMAGNETIC WAVES
SEE RADIATION, ELECTROMAGNETIC WAVES
ELECTROMYOGRAPHY
SEE MUSCLE FUNCTION, ELECTROMYOGRAPHY*
ELECTRON ACCELERATORS
SEE RADIATION, PARTICLE ACCELERATORS
ELECTRON CHARGE DISTRIBUTION
SEE ALSO ELECTRICITY MAGNETISM, DIELECTRIC PROPERTIES
SEE ALSO ELECTRICITY-MAGNETISM, DIPOLE MOMENTS
ROlHL-13164-07 Interaction ot the alpha and beta chains
of human hemoglobin
P50HL1414708 0015 Specialized center of research in
thrombosis - Charge related properties of phospholipid
surfaces in monolayers and vesicles
ROIHL 16601-05
(human, cattle)
ROIHL 16860-05
hemoproteins
ROlHL-18737-03
Structure and function of blood proteins
Mossbauer studies of respiratory
Human erythrocyte membrane structure
ELECTRON DENSITY
SEE ELECTRON CHARGE DISTRIBUTION
ELECTRON MICROSCOPY
SEE OPTICS, MICROSCOPY, ELECTRON*
ELECTRON-PAIR BONDS
SEE CHEMICAL BONDS, COVALENT
ELECTRON PARAAAAGNETIC RESONANCE
SEE CHEMISTRY, ANALYTICAL METHODS, SPECTROMETRY,
ESR*
ELECTRON PROBE
SEE CHEMISTRY, ANALYTICAL METHODS, SPECTROMETRY.
ELECTRON PROBE-
ELECTRON SPIN RESONANCE
SEE CHEMISTRY. ANALYTICAL METHODS. SPECTROMETRY,
ESR*
ELECTRON SPIN (UNPAIRED)
SEE CHEMISTRY, ANALYTICAL METHODS, SPECTROMETRY,
ESR*
ELECTRON TRANSPORT
SEE CHEMICAL TRANSFER, ELECTRON TRANSPORT
ELECTRONARCOSIS
SEE SENSORY DEPRESSION, ELECTRONARCOSIS
ELECTRONIC HEART STIMULATORS
SEE HEART PACEMAKERS ELECTRONIC
ELECTRONIC NEUROMUSCULAR STIMULATORS
(FOR NEUROMOTOR DISORDERS)
SEE NEUROMUSCUUR STIMUUTORS (FOR NEUROMOTOR
DISORDERS)
ELECTRONIC RECORDING SYSTEMS
SEE BIOMEDICAL SYSTEMS AUTOMATED, ELECTRONIC
RECORDING SYSTEMS
ELECTRONIC RESPIRATORY STIMULATORS
SEE RESPIRATORY ASSIST AND OXYGEN ADMINISTRATION,
ELECTRONIC RESPIRATORY STIMULATORS
Reactions of hemeproteins and oxygen
*Excludes routine methodotogy OR covers only general projects whicii preclude indexing at the specific level.
**Onented significantly to above subject.
ELECTRONIC SPECTRA
Ml AIMI LHIMICAI HONO'>
SEE A1S0CHIMI(.AI HIJNU'. VIRNAIinNS
SfE ALSO CHfMISIHY. ANAIYIICAI Ml IHOtlS,
SPECIROMIIRY*
SEC ALSO METALS, OIVAIINI Ml lAI ',
SEE ALSO OPTICS. CHROMOPHOHI *
** ROIHI 16087 05 Structural and dynamic itudy ol modll
heme complexes (yeast)
" NOIHV 32913 II Study elertroddes^ glow diicharga lor
iiioditymg (lulymei siirtare
ELECTRONIC SPECTRA, ATOMIC ORBITAIS
•• POIHL 16833 04 OU08 Hemoglobin and red cell system in
hemoglobinopalhie% Membrane associated phenomena in
SS disease
ELECTRONIC SPECTRA, FREE RADICALS
POIHL 06314 17 0047 Immunologic mechanisms in
cardiovascular disease Role of intravascular coagulation
(human, animals)
** POIHL 06370 17 0006 Cardiopulmonary and renal
pathology research center Chemical basis of
ultrastructural changes in disease (rats)
ROIHL 15104 07 A mechanism for oxidative
phosphorylation
ROIHL 15980 06
(cattle)
** ROIHL 16029 05 Bio organic chemistry of ozone, nitrogen
dioxide and tobacco smoke
ROIHL 1953201 Oxygen toxicity in the red cell (human)
•* R23HL 22621 01 Blood cell mediated pulmonary (human)
ELECTRONIC SPECTRA, MOLECULAR ORBITALS
** ROIHL 15391-07 EPR studies on rotational motion of
myosin and actio
ROIHL 2148301 Electronic, thermodynamic and kinetics
of hemoglobin
ROlHL-22432 01 Molecular studies of human erythrocyte
membranes
ELECTRONIC SPECTRA, SINGLET STATE
ROIHL 13652 08 Metal sites in metalloproteins
(mushroom)
ELECTRONIC STIMULATORS (GENERAL)
SEE ALSO BRAIN STIMULATORS ELECTRONIC
SEE ALSO HEART PACEMAKERS ELECTRONIC
SEE ALSO NEUROMUSCULAR STIMUUTORS (FOR
NEUROMOTOR DISORDERS)
SEE ALSO RESPIRATORY ASSIST AND OXYGEN
ADMINISTRATION, ELECTRONIC RESPIRATORY
STIMUUTORS
ROIHL-08696-15 0020 Orthotopic heart transplantation -
Complete cardiopulmonary transplantation (dogs)
** ROlHL-22844-01 Phrenic nerve pacing -Noninvasive
diaphragm analysis (human, dogs)
ELECTRONIC STIMULATORS, RAOIOFREQUENCY
CONTROLLED
** ROlHL-04651-19 Remote stimulation by radio-frequency
transmission (dogs, human)
R01HL04666-19 Artificially paced hearts-Technology,
physiology (human, dogs)
** ROlHL-21706-02 Nuclear magnetic resonance and
myocardial ischemia (rats)
ROIHL 22844-01 Phrenic nerve pacing-Noninvasive
diaphragm analysis (human, dogs)
ELECTROPHORESIS
SEE PHYSICAL SEPARATION. ELECTROPHORESIS*
ELECTROPHRENIC STIMULATORS
SEE RESPIRATORY ASSIST AND OXYGEN ADMINISTRATION,
ELECTRONIC RESPIRATORY STIMUUTORS
ELECTROPHYSIOLOGY
SEE ALSO BRAIN ELECTRICAL ACTIVITY
SEE ALSO ELECTROPOTENTIALS
SEE ALSO ELECTROSTIMULUS
SEE ALSO NEUROPHYSIOLOGY (GENERAL)
R01HL00082-30 Transmembrane movements (barnacles,
frogs, rats)
** ROlHL-01486-23 Quantitative study of T-wave mechanisms
(human, rabbits, dogs, chickens)
R01HL05806-I8 Analysis of antiarrhythmic agents (dogs,
rabbits)
** ROlHL-05883-18 0004 Reflex control of resistance and
capacitance vessels Lett ventricular receptors with
nonmedullated vagal afferents (cats)
** ROlHL-05883-18 0005 Reflex control of resistance and
capacitance vessels Differential blockade of medullated
and nonmedullated vagal afferents in the cat
ROlHL-0588318 0006 Reflex control of resistance and
capacitance vessels - Cardiopulmonary vagal afferents in
the conscious dog
P01HL06285 18 0196 Cardiovascular-respiratory
physiology and biochemistry - Hormonal regulation of
sodium transport Epithelial cell membranes (toads)
M POlHL-06308 18 Mechanisms and therapy of circulatory
disease
•* POlHL-06308-18 0011 Mechanisms and therapy of
circulatory disease - Blood flow and electrical dysfunction
in ventricular arrhythmia (human)
(contd)
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
ELE
** POlHL-06308-18 0025 Mechanisms and therapy of
circulatory disease • Subcellular calcium pools in the
genesis of arrhythmias (dogs)
** POlHL-0630818 0029 Mechanisms and therapy of
circulatory disease - Characterization of the patient with
recurrent ventricular arrhythmias
** POlHL-06308-18 0035 Mechanisms and therapy of
circulatory disease - Mechanisms for electrophysiological
changes in myocardial infarction (dogs)
POlHL-06308-18 0037 Mechanisms and therapy of
circulatory disease - Electrophysiology, blood flow, and ANS
in ventricular fibrillation (dogs)
** P01HL06308-18 0039 Mechanisms and therapy of
circulatory disease • ANS in regulation of electrophysiology -
Role of cyclic nulceotides (animals)
** POlHL-06308-18 0040 Mechanisms and therapy of
circulatory disease - Metabolism and fatty acid utilization -
Heart electrical stability (rats, dogs)
P01HL06308-18 0042 Mechanisms and therapy of
circulatory disease • Echocardiographic assessment of
arrhythmias-Myocardial tissue type (human, dogs)
POlHL-06308-18 0044 Mechanisms and therapy of
circulatory disease - Echocardiography to determine site of
ectopic impulse formation (human, dogs)
P01HL06312-17 0025 Surgical cardiology • Effect of
denervation on arrhythmias and function with coronary
occlusion (dogs)
** POlHL-0631417 0054 Immunologic mechanisms in
cardiovascular disease - Physiology of cell communications
(mice, frogs, guinea pigs)
** R01HL07139-17 Cardiodynamics and metabolism of
congestive failure (human, dogs)
R01HL0777615 Sudden death and cardiac arrhythmias
(human, dogs, cats)
POlHL-07896-15 0008 Environmental biomedical research
program - Otologic studies under hyperbaric conditions
(human, animals)
POlHL-0789615 0029 Environmental biomedical research
program - Oxygen-helium diving resulting In high pressure
nervous syndrome (human, animals)
P01HL07896-15 0030 Environmental biomedical research
program - Narcosis caused by inert gases at raised
pressures (human, animals)
POlHL-07896-15 0062 Environmental biomedical research
program ■ Vectorcardiograms during diving (human, dogs)
** ROlHL-08508-15 Cardiac conductivity and automaticity
(human, dogs, rabbits)
M P01HL08682-15 Regulation of the cardiovascular system
** POlHL-08682-15 0015 Regulation of the cardiovascular
system - Projection of autonomic nerves onto the heart
(dog)
** P01HL0868215 0016 Regulation of the cardiovascular
system • Shifting cardiac pacemakers and AV nodal
activation (dog)
** POlHL-08682-15 0017 Regulation of the cardiovascular
system - Neurally induced cardiac dysrhythmias (dog)
** POlHL-0868215 0018 Regulation of the cardiovascular
system - Functional implications of cardiac afferent nerves
(dogs)
POlHL-08682-15 0022 Regulation of the cardiovascular
system • Blood pressure responses and preganglionic
sympathetic outflow (cat)
" POlHL-08682-15 0025 Regulation of the cardiovascular
system - Physiology of preganglionic cell bodies (cat)
** POlHL-08682-15 0031 Regulation of the cardiovascular
system - Cardiac electrophysiology in hibernation (ground
squirrel, marmot)
" POlHL-08682-15 0037 Regulation of the cardiovascular
system - Central nervous regulation of cardiopulmonary
mechanisms (cats)
POlHL-0889914 0030 Tolerance to respiratory gases in
health and disease ■ Dynamic characteristics of respiratory
control components (human, cats)
ROlHL-1050313 Cardiac ion transport and ultrastructure
(rats, guinea pigs, rabbits)
** ROlHL-10897-12 Effects of hormones on cardiac
electrogenesis (rabbits, guinea pigs, dogs)
M POIHLI 1307-12 Biophysical studies in pediatric
cardiology
"* POlHL-1130712 0002 Biophysical studies in pediatric
cardiology - Cardiac extracellular electrophysiology (human,
dog, chimpanzee)
POlHL-1130712 9001 Biophysical studies in pediatric
cardiology - Core support-computer science
** POIHL 11307 12 9002 Biophysical studies in pediatric
cardiology - Biomedical engineering
M POlHL-11310-12 Mechanisms of cardiovascular disease
*• POlHL-11310-12 0071 Mechanisms of cardiovascular
disease - Electrophysiological studies of atrial flutter
(human)
" POIHL 11310-12 0072 Mechanisms of cardiovascular
disease - Electrophysiological studies of atrial tachycardia
with block (human)
•* POlHL-11310-12 0073 Mechanisms of cardiovascular
disease - Electrophysiological study of atrial fibrillation
(human)
** POlHL-11310-12 0074 Mechanisms of cardiovascular
disease - Electrophysiological studies of paraxysmal atrial
tachycardia (human)
** POlHL-l 1310-12 0075 Mechanisms of cardiovascular
disease - Bipolar atrial electrograms from Bachmann's
bundle (dogs)
192
POIHL 11310-12 0077 Mechanisms of cardiovascular
disease - Abnormalities of rhythm and conduction following
heart surgery (human)
** POlHL-11310-12 0079 Mechanisms of cardiovascular
disease - Electrophysiological studies of complete heart
block (human)
** POlHL-11310-12 0087 Mechanisms of cardiovascular
disease - Electrophysiology and electropharmacology of the
heart (dogs)
M POlHL-11351-12 Cellular and molecular mechanisms of
myocardial function
** POlHL-11351-12 0003 Cellular and molecular
mechanisms of myocardial function - Mechanical and
electrical properties of cardiac muscle (rabbits)
** POlHL-11351-12 0005 Cellular and molecular
mechanisms of myocardial function - Electrophysiology of
cardiac muscle (rats)
** POlHL-11351 12 0020 Cellular and molecular
mechanisms of myocardial function - Electrophysiology of
cultured heart cells
P01HL12157-11 0055 Functions and mechanisms of cell
membrane ion transport ■ Growth and development of
synthetic strand heart cells in culture (chick embryo)
POlHL-12157-11 0057 Functions and mechanisms of cell
membrane ion transport - Electrophysiological
investigations of synthetic strands of heart muscles (rats)
ROlHL-12611-10 Basic and clinical studies of the ST-T
deflection (human, dogs)
POlHL-12738-10 0001 Physiologic pharmacology and its
clinical applications - Clinical pharmacology of cardioactive
drugs (human)
POlHL-12738-10 0035 Physiologic pharmacology and its
clinical applications - Function and dysfunction of the
sinoatrial node (human)
** POlHL-12738-10 0044 Physiologic pharmacology and its
clinical applications - Cardioactive drugs and
electrophysiological properties of cardiac cells (sheep)
*• POlHL-12738-10 0076 Physiologic pharmacology and its
clinical applications - Pediatric cardiac electrophysiology
and pharmacology (human, dogs)
** POlHL-12738-10 0080 Physiologic pharmacology and its
clinical applications - Electrophysiology of cardiac muscle
in the mitral valve (monkeys)
** POlHL-12738-10 0081 Physiologic pharmacology and its
clinical applications - Ultrastructural and electrophysiologic
alteration of myocardium (human, dogs)
** POlHL-12738-10 0107 Physiologic pharmacology and its
clinical applications - Blood supeilused cardiac fibers
(dogs)
" POlHL-12738-10 0108 Physiologic pharmacology and its
clinical applications - Developmental electrophysiology and
pharmacology (human, animals)
** POlHL-12738-10 0110 Physiologic pharmacology and its
clinical applications - Physiology and pharmacology of
arrhythmias (dogs)
** POlHL-12738-10 0127 Physiologic pharmacology and its
clinical applications - Cardiac electrical activity (human,
animals)
POlHL-12738-10 0135 Physiologic pharmacology and its
clinical applications - Myocardial cells in tissue culture
(rats, chick embryo)
" POlHL-12738-10 0136 Physiologic pharmacology and its
clinical applications -
M POlHL-13108-09 Clinical heart transplantation
** POlHL-13108-09 0008 Clinical heart transplantation ■
Physiology and pharmacology of the transplanted human
heart
** POlHL-13108-09 0017 Clinical heart transplantation -
Electrophysiology of the transplanted denervated human
heart
** POlHL-13108-09 0018 Clinical heart transplantation -
Electrophysiologic studies of cardiac drugs in the
denervated heart
** ROlHL-13134-07 Mechanism of chemoreceptor discharge
(cats)
ROlHL-13187-09 Central neural control of cardiovascular
function (cats)
ROlHL-13306-08 Pharmacological control of cardiac
membrane currents (cattle, rabbits)
ROlHL-13339-08 Pharmacology of developing cardiac
tissues (chick embryo)
** R01HL13375-09 Cellular potential changes causing
cardiac arrhythmias (dogs)
ROlHL-13427-09 Neural control of blood volume (monkeys,
dogs)
M POlHL-13480-09 Cardiac electrophysiology
** POlHL-13480-09 0017 Cardiac electrophysiology - Body
surface potential mapping (human, dogs)
** POlHL-13480-09 0026 Cardiac electrophysiology - Neural
influences on cardiac electrophysiology and contraction
(dog, cat)
** POlHL-13480-09 0028 Cardiac electrophysiology - Stress
electrocardiography (human, dogs)
** POlHL-1348009 0032 Cardiac electrophysiology - Cardiac
activation sequence (dogs)
** POlHL-13480-09 0042 Cardiac electrophysiology ■
Computer modeling of arrhythmias
POlHL-13737-07 0030 Assisted circulation - Myocardial
ischemia -Effects of phase-shift balloon pumping (dogs)
ROlHL-13988-07 Elimination of reoperative cardiac
pacemaker surgery (dogs)
Cerebral arterial tone and reactivity
Evaluation of heart stimulants in sea
Electrophysiology of fibrillation and
ELE
P50HL-14159-08 0018 Specialized center of research in
hypertension - Sympathetic nervous system in hypertension
(rats)
P50HL-1421407 0027 Newborn lung center for hyaline
membrane disease - Orallaryngeal chemoreceptors and
respiratory failure in newborns (human, sheep)
POlHL-14388-07 0152 Regulation of the circulation in
pathological states - Ion flux alterations in caudal artery In
SHR
POlHL-14388-07 0178 Regulation of the circulation in
pathological states - Structural and functional
consequences of denervation (rats)
P01HL14388-07 0201 Regulation of the circulation in
pathological states - Central sympathetic discharge in
spontaneously hypertensive rats
POlHL-14414-07 0010 Environmental influences on
cardiorespiratory and cellular functions ■ Pressure effects
on cardiac electrical phenomena (animals)
POlHL-14414-07 0014 Environmental influences on
cardiorespiratory and cellular functions • Temperature and
acid-base status in tissues, cells, and subcellular system
' ROlHL-14614-07 Voltage control of contraction in heart
(sheep)
ROlHL-14717-06 Hemodynamics and heart structure-
Ventricular overload (dogs)
" ROlHL-14899-07 Mechanism and prevention of cardiac
arrhythmias (dogs)
> P50HL15061-07 0005 Response of lung to injury - Airway
smooth muscle in health and disease (dogs, guinea pigs)
' ROlHL-15190 07 Physiological basis of arrhythmias and
their therapy (human)
* POlHL-15194-07 0004 Pathophysiology of
cardiopulmonary dysfunction - Specialized electrophysiology
fibers -Electrogenic basis of glycosides (mammals)
ROlHL-15740-06 In vitro studies on heart cell function
(rats)
ROIHL- 1580506
(rabbits)
ROlHL-15991-05
anemones
* ROlHL-16076-06
defibrillation (human)
POlHL-161 17-05 0004 Ion movements and membranes in
cardiovascular control - Optical studies of excitation-
contraction coupling (frogs, snakes)
ROlHL-16135-05 Mechanisms of cardiac autorhythmicity
(dogs, bats)
* ROlHL-16152-06 Electrophysiology of neonatal to adult
heart (cats, frogs, guinea pigs)
ROlHL-16315-05 Analysis of interaction between CNS
vasomotor systems (cats, rats)
R01HL16318-21 Biochemistry and pharmacology of Na-K
transport
* ROlHL-1632805 Membrane electrical properties of
vascular muscle (human, animals)
R01HL16430-05 Neural control of respiration (cats)
ROlHL-1650704 Heart cell interactions and cell junction
biogenesis (mice, rats, rabbits)
ROlHL-16511-04 Sympathetic afferent activity of cardiac
origin (dogs, monkeys)
■* ROlHL-16567-04 Differentiation of the heart-cell
membrane (mice, chick)
POlHL-16607-05 0001 Calcium ion and control of
cardiovascular function - Bilayer lipid membranes,
antibiotic probes, and SR function
ROlHL-16648-16 Integrated control of cardiovascular
activity (cats)
P01HL16878-05 0003 Control of ventilation in health
and disease - Brain stem respiratory neurons in response
mechanical/chemical loading (animal)
POlHL-16878-05 0004 Control of ventilation in health
and disease - Neurotransmitters in the respiratory system
(cats)
P60HL-17269-04 0007 National heart and blood vessel
research and demonstration center - Correlative studies of
experimental myocardial ischemia (dog)
ROIHL- 17322-04 Functional characteristics of smooth
muscle isolated from lung (animals)
R01HL-17370-03 Synaptic chemistry and cardioregulation
in Limulus
ROlHL-17451-05
mechanisms
ROlHL-17532-04
in dogs
** P50HL-17648-04 0014 Study of ischemic heart disease -
Antidysrhythmic drugs and mammalian cardiac Purkinje
fibers (sheep, dog)
** P50HL-17648-04 0028 Study of ischemic heart disease -
Electrophysiology of sympathetic innervation in tissue
culture
** P50HL-17651-04 0022 Ischemic heart disease specialized
center of research - Electrophysiology-Mechanism and
pharmacology of arrhythmias (human, dog)
** P50HL-17651-04 0046 Ischemic heart disease specialized
center of research - Clinical core-Physiological
changes/biochemical effects of myocardial ischemia
P50HL-17667-04 0031 Study of ischemic heart disease •
Pathophysiology in ischemic heart disease (dog, cat, rabbit,
monkey)
** P50HL-17670-04 0008 Study of ischemic heart disease -
Surgical treatment of cardiac rhythm disorders (human,
dogs)
(contd)
Digitalis effects on cardiac automaticity
Infarct size-ECG, angio, path, correlation
•Excludes routine methodology OR covers only general projects which preclude indexing at tlie specific level-
••Qriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
■u
)93
■U
Role ot Na. K ATPase inhibition on
Elcctrophysioloiy of haarl cells (rats.
ROIHl 17800 04 Pulmonary lellatas Canlial pathways
(cats. do|s. labbitsl
ROIHL l/90;04 Biam ie|ulalion ol cardiac airhythmia
(pi|s. cats, rats)
ROIHL lgOI&03 Pharmacoloiic studies on vasculai
smooth muscle (dogs, rats)
ROIHL 18032 03 Development ol normal and myopathic
mammalian heart (hamsters)
ROIHL I80!i3 03 Intracellular ionic activities m heart
muscle (trogs)
ROIHL 18398 04 Mechanisms ol delayed and asymetiic
ventricular conduction (human, dogs)
ROIHL 18S38 03 The role ol electrotonus In His Purklnje
function (dog)
ROIHL 18S9803
digitalis action
ROIHL 18/1103
chicks)
ROIHL 1879S 04 Ischemic arrhythmias Efled ol
autonomic tone (dogs. rats, guinea pigs)
ROIHL 1879604 Experimental cardiac arrhythmias (dogs)
ROIHL 1894303 Contractile activity of single cardiac cells
POIHL 1897403 0001 Experimental neurogenic
hypertension program Central neural systems regulating
arterial pressure (rabbits)
POIHL 18974 03 0006 Experimental neurogenic
hypertension program Model of sustained arterial
hypertension (cats)
ROIHL 1904403 Effect ot drugs on development of
cardiac failure (cats)
ROIHL 1904503 Electrophysiology of cardiac automaticity
(human, dogs)
ROIHL 19048-03 Structure of baroreceptors in
hypertension (rats)
ROIHL 1907603 Vagal control of heart rate- A biophysical
model (rabbits)
ROIHL 1913803 Contractile activation of skinned cardiac
cells (mammals)
R01HL19216-03 Characterization of cardiac pacemaker
activity (cat. dog. rabbit)
P01HL1924202 Study of vascular smooth muscle
POlHL-19242-02 0002 Study of vascular smooth muscle •
Vascular smooth muscle response to serum lipoproteins
(rats)
P01HL1924202 0009 Study of vascular smooth muscle ■
Electrophysiology of vascular smooth muscle (rats, chick
embryo)
POlHL-19259-03 0004 Digoxin-specific antibody in human
therapy - Digitalis-specific antibodies pharmacological
studies (human, dogs, sheep)
ROIHL- 19398-03 Regional conduction abnormalities and
arrhythmias (dogs)
ROlHL-19487-03 Cardiac actions of digitalis (dogs, cats)
ROlHL-19768-02 Recording and analysis of low levels
c diac signals (human, dogs)
ROlHL-19995-02 Sensory transduction in cardiac
mechanoreceptors (cats, frogs, rats)
ROlHL-20153-02 Intracellular pH and myocardial
electropharmacology (dogs, guinea pigs)
ROIHL 20238-02 Prospective bundle branch block study
(human)
ROlHL-20558-02 Cardiac electrophysiology-Effects of ions
and drugs
POlHL-20581-01 0001 Vascular neuroeffector
mechanisms in health and disease - Vascular neuroeffector
mechanism (rabbits)
POlHL-20581-01 0003 Vascular neuroeffector
mechanisms in health and disease - Cerebrovascular
neuroeffector characteristics (animals)
POlHL-2058101 0005 Vascular neuroeffector
mechanisms in health and disease - Changes in the
neuroeffector mechanism in hypertension (rabbits)
POlHL-20592-02 Cell biology of cardiac and skeletal
muscle
POlHL-20592-02 0003 Cell biology of cardiac and
skeletal muscle - Cellular magnesium and anion activities
in ion-specific microelectrodes (frogs)
POlHL-20592-02 0004 Cell biology of cardiac and
skeletal muscle - Excitation, conduction and contraction-
Modelling in Purkinje fibers
POlHL-20592-02 0005 Cell biology of cardiac and
skeletal muscle - Quantitative voltage studies
POlHL-20592-02 0006 Cell biology of cardiac and
skeletal muscle - Permeability and ultrastructure of cardiac
nexuses (rabbits, cattle, rats)
ROlHL-20597-02 Electrophysiologic correlates of
myocardial ischemia (human, dogs, rabbits)
ROlHL-20847-02 Respiratory neurochemical control
(human, goats)
ROlHL-20864-01 Postnatal maturation of cardiovascular
regulatory system (minipig)
ROlHL-21014-01 Mechanism of the inotropic action of
cardiac glycosides
ROlHL-21 136-02 Ion activities and transport in cardiac
muscle cells (sheep)
ROlHL-21145-02 Response of atria to hyperosmolality-
Mechanisms (rabbits)
R23HL-2 1151-02 Ischemic myocardium-Delivery of blood
flow and drugs (dogs)
R23HL-21167-02 The electrophysiology of cardiac
hypertrophy (rats)
ROIHI 21794 07 Voltage clamp ol isolated cardiac
Puikinie calls (dogs)
ROIHL 71317 01 Sarcomere mechanics in disrupted
ventricular muscle (guinea pigs)
ROIHI 71314 07 Respiratory tract secretion of ions, water
and mucus (human, dogs)
ROIHI 71347 07 Isolation and inilyilt ol lodlum chinnti
from heart (frogs)
R73HI 71347 07 Accessory pathways and supraventricular
tachycardia
ROIHL 71351 0? Renal and vascular control by
sympathetic ganglia (animals)
R23HL 21368 02
R01HL2152;01
(human)
ROIHL 71574 01
tissues (dogs)
R01HL7165401
due to ischemia (cats)
R01HL7167701
cardiac cells
R01HL2173501
infarction (cats)
R23HL2178301 Ionic control of contractility in anoxic
myocardium (rabbits, rats)
R23HL2191401 Studies of vasomotor control (rats)
ROIHL 2213501 Control of calcium fluxes across cardiac
membranes (dogs, rabbits, guinea pigs)
ROlHL-22235-01
(rabbits)
R23HL 2224502
Perinatal cardiac electrophysiology (dogs)
Prospective study of bundle branch block
Automaticity of AV node and its adjacent
Autonomic determinants of arrhythmia
:ats)
Antiarrhythmic drug action on VMAZ of
Electrophysiology after healed myocardial
Mechanism of cardiac pacemaking
Functional characteristics of atrial
receptors (rats)
ROlHL-22269-01 Excitation-contraction coupling in
enlarged hearts (rabbits)
ROIHL 22418-01 Neural control of cardiorespiratory
function (cats)
ROlHL-22470'01 Liposome myocardial uptake in infarct
and ischemia (dogs. rats, mice)
ROIHL 22594-01
failure (dogs)
ROIHL 22715-01
reflexes (dogs))
R23HL-22728-01
ROlHL-22732-01
nerves (cats, monkeys)
ROIHL 22862-01
drugs (dogs)
ROlHL-23071-01
(dog. human)
R13HL-2307201
Reflex control of the circulation in heart
Neural integration of the cardiovascular
Neural control of renin secretion (dogs)
Central organization of cardiac afferent
CNS-mediated effects of antiarrhythmic
Electrophysiology of lethal arrhythmias
Gordon Research Conference-Cardiac and
lew Hampshire)
Voltage dependent conductance in
Mechanisms of ischemic rhythm
Pharfnacology of relaxation in smooth
skeletal muscle (New Hampshire)
ROlHL-23183-01
membranes
" ROlHL-23599-01
disorders (dogs)
ROlHL-236 14-02
muscle (mollusks)
ROIHL 23624-01 Effect of drugs on ischemic cardiac cells
(dogs, guinea pigs, pigs)
** R01HL-23970-01 Mechanisms and control of sudden
cardiac death (human, dog)
ELECTROPOTENTIALS
SEE ALSO ELECTRICAL IMPEDANCE
SEE ALSO ELECTRODES-
P01HL06285-18 0180 Cardiovascular-respiratory
physiology and biochemistry - Vagal C-fibers and their
influence on visceral and somatic function (animals)
** POlHL-12157-11 0060 Functions and mechanisms of cell
membrane ion transport - Ion transport and electrical
properties of giant-celled aiga
POlHL-12738-10 0135 Physiologic pharmacology and its
clinical applications - Myocardial cells in tissue culture
(rats, chick embryo)
POlHL-1273810 0136 Physiologic pharmacology and its
clinical applications -
ROIHL-19995-02 Sensory transduction in cardiac
mechanoreceptors (cats, frogs, rats)
ROlHL-2023002 Analysis of the action potential of
cardiac muscle (sheep)
** ROlHL-22738-01 Role of bioelectric potentials in platelet
adherence (bats. rats, hamsters)
ELECTROPOTENTIALS, ACTION POTENTIALS
" POlHL-06308-18 0035 Mechanisms and therapy of
circulatory disease - Mechanisms for electrophysiological
changes in myocardial infarction (dogs)
POlHL-08682-15 0018 Regulation of the cardiovascular
system - Functional implications of cardiac afferent nerves
(dogs)
POlHL-08682-15 0031 Regulation of the cardiovascular
system - Cardiac electrophysiology in hibernation (ground
squirrel, marmot)
POlHL-1 1307-12 0003 Biophysical studies in pediatric
cardiology - Cellular biophysics (animals)
P01HL11351-12 0015 Cellular and molecular
mechanisms of myocardial function - Effects of hypoxia
and ischemia on ion exchange and heart function (rabbits)
POlHL-11351-12 0020 Cellular and molecular
mechanisms of myocardial function - Electrophysiology of
cultured heart cells
Physiologic pharmacology and its
-Exdudes routine methodok)gy OR covers only general projects which preclude indexing at the specific level.
•-Oriented significantly to above subject.
" POIHI 1715/ II 0057 functiont and mtchaniimi ot c«ll
membrane ion Irantport Active •leclriral pioparlMt ot the
synthetic strand
POIHI 1715/ II 005/ Function-, and mirhaniimt ol call
membrane ion transport (leclrophy.iologiral
investigalions ol synthetic strands ol heart muscles (rati)
POIHL 17738 10 0044 Physiologic pharmacology and its
clinical applications Cardioactive drugs and
electrophysiological properties of cardiac cells (she«pj
POIHI 17/38 10 00/6 Physiologic pharmacology and it-.
clinical applications Pediatric cardiac electrophysiology
and pharmacology (human, dogs)
POIHL 17/38 10 0081 Physiologic pharmacology and itt
clinical applications Ultrastructural and electrophysiologic
alteration of myocardium (human, dogs)
POIHL 17738 10 0107 Physiologic pharmacology and itt
clinical applications Blood tuperfused cardiac fibcri
(dogs)
POIHL 12738 10 0108 Physiologic pharmacology and its
clinical applications Developmental electrophysiology and
pharmacology (human, animals)
POIHL 12738 10 0135 Physiologic pharmacology and its
clinical applications Myocardial cells in tissue culture
(rats, chick embryo)
POIHL 12738 10 0136
clinical applications
ROIHL 13306-08 Pharmacological control of cardiac
membrane currents (cattle, rabbits)
** ROIHL 1333908 Pharmacology of developing cardiac
tissues (chick embryo)
** ROIHL 13349-06 Analysis of activation process in heart
muscle (guinea pigs, rabbits, human)
POIHL 14414-07 0016 Environmental influences on
cardiorespiratory and cellular functions - Effects of
pressure on membrane and cellular function (human,
rabbits)
ROIHL 14614-07 Voltage control of contraction in heart
(sheep)
ROIHL 14899-07 Mechanism and prevention of cardiac
arrhythmias (dogs)
POIHL 1519407 0004 Pathophysiology of
cardiopulmonary dysfunction - Specialized electrophysiology
fibers-Electrogenic basis of glycosides (mammals)
ROlHL'15985-06 Metabolic and hormonal control of
cardiac contraction
ROlHL-16152-06 Electrophysiology of neonatal to adult
heart (cats, frogs, guinea pigs)
ROlHL-16657-06 Innervation of coronary arteries and heart
(rats)
ROlHL-17451-05 Digitalis effects on cardiac automaticity
mechanisms
P50HL17648-04 0014 Study of ischemic heart disease
Antidysrhythmic drugs and mammalian cardiac Purkinje
fibers (sheep, dog)
P50HL- 17648-04 0028 Study of ischemic heart disease -
Electrophysiology of sympathetic innervation in tissue
culture
ROlHL'18032-03 Development of normal and myopathic
mammalian heart (hamsters)
ROlHL-18538-03 The role of electrotonus in His-Purkinje
function (dog)
ROlHL'19216-03 Characterization of cardiac pacemaker
activity (cat, dog, rabbit)
ROlHL-20122-02 Operational mechanisms of airway
receptors (dogs, pigs)
" ROlHL-2023002 Analysis of the action potential of
cardiac muscle (sheep)
ROlHL-2055802 Cardiac electrophysiology-Effects of ions
and drugs
ROlHL-20708-02 Voltage clamp of embryonic heart cell
aggregates (rat and chick embryos)
ROlHL-2 1283-02 Simulation studies of the ECG in acute
ischemia (and human)
** ROlHL-21342-02 Isolation and analysis of sodium channel
from heart (frogs)
R23HL-21368-02 Perinatal cardiac electrophysiology (dogs)
ROlHL-21670-01 Antiarrhythmic studies on 2-substitutcd
aminoindenes (dogs)
ROlHL-21672-01 Antiarrhythmic drug action on VMAZ of
cardiac cells
ROlHL-21735-01 Electrophysiology after healed myocardial
infarction (cats)
ROlHL-2186018 Factors influencing responses to
adrenergic drugs (guinea pigs, rats, cats)
** ROlHL-22239-01 The molecular basis of electrical
excitability (chick embryos, rats)
** ROlHL-22269-01 Excitation-contraction coupling in
enlarged hearts (rabbits)
** ROlHL-22426-01 Initiation of the heartbeat -A voltage-
clamp study (bullfrogs, rabbits)
** ROlHL-22562-02 Mechanism of cardiac action potential
propagation (tunicates)
" ROlHL-22767-01 Model system for cardiac action
potentials (squid, axons)
ROlHL-23624-01 Effect of drugs on ischemic cardiac cells
(dogs, guinea pigs, pigs)
ELECTROPOTENTIALS, EVOKED POTENTIALS
POlHL-07896-15 0032 Environmental biomedical research
program - Fluorometry study of brain exposed to hyperbaric
oxygen (dogs, cats)
(contd)
M Grant has subprojects describing specific research aspects.
See Appendix for Investigator's name and grant number.
ELE
194
ELE
POlHL-07896-15 0051 Environmental biomedical research
program - Relationships of retinal circulation to disease
(rabbits)
POlHL-0789615 0056 Environmental biomedical research
program ■ Neuromuscular blocking effects of
nondepolarizing muscular relaxants (frogs)
POlHL-08805-15 0046 Regulation of ventilation and
pulmonary circulation - Sites and modes of interaction of
peripheral and central chemoreceptors
*• P50HL-14214-07 0032 Newborn lung center for hyaline
membrane disease - Evoked electroencephalographlc
potential in Infants with HMD (human)
P50HL-19187-02 0011 Pediatric pulmonary SCOR-Hyallne
membrane disease - Effects of hypoxia and hypercapnia on
developing nervous system (monkey, human)
ELECTROPOTENTIALS, MEMBRANE POTENTIALS
SEE ALSO ELECTROPOTENTIALS. ZETA POTENTIAL
ROlHL-01486-23 Quantitative study of Twave mechanisms
(human, rabbits, dogs, chickens)
POlHL-06285-18 0199 Cardiovascular-respiratory
physiology and biochemistry - Renal tubular reabsorption of
sodium chloride (hamsters, rabbits)
POlHL-0666417 0037 Cardiopulmonary function in
remediable vascular disease - Salt and water balance of
cells and tissues (rabbits)
ROlHL-08508-15 Cardiac conductivity and automaticlty
(human, dogs, rabbits)
POlHL-08682-15 0031 Regulation of the cardiovascular
system - Cardiac electrophysiology In hibernation (ground
squirrel, marmot)
** ROlHL-0990613 0019 Membrane transport processes in
red blood cells - Hemoglobin change and membrane
potentials in red blood cells at varying volumes
** ROlHL-09906-13 0020 Membrane transport processes in
red blood cells ■ Calibration of a fluorescent probe for
erythrocytes
** ROlHL-09905-13 0021 Membrane transport processes in
red blood cells - Membrane potentials In human red blood
cells due to proton gradients
ROlHL-10503-13 Cardiac ion transport and ultrastructure
(rats, guinea pigs, rabbits)
ROlHL-10897-12 Effects of hormones on cardiac
electrogenesls (rabbits, guinea pigs, dogs)
POlHL-11307-12 0003 Biophysical studies in pediatric
cardiology - Cellular biophysics (animals)
POlHL-1131012 0087 Mechanisms of cardiovascular
disease - Electrophysiology and electropharmacology of the
heart (dogs)
P01HL-1135M2 0005 Cellular and molecular
mechanisms of myocardial function - Electrophysiology of
cardiac muscle (rats)
POlHL-12157-11 0049 Functions and mechanisms of cell
membrane ion transport - Ouabain-insensitive cation
transport in duck red cells
POlHL-12157-11 0052 Functions and mechanisms of cell
membrane Ion transport ■ Active electrical properties of the
synthetic strand
P01HL-12157-U 0054 Functions and mechanisms of cell
membrane ion transport • Simulation of electrogenic ion
transport in cardiac muscle
** POlHL-12157-11 0057 Functions and mechanisms of cell
membrane Ion transport • Electrophysiological
investigations of synthetic strands of heart muscles (rats)
POlHL-12373-10 0012 Cardiopulmonary physiology and
pathophysiology ■ Biochemistry of the sympathetic nervous
system (rats, rabbits, pigeons)
ROiHL-1269009 Systemic and local vascular adjustment
In shock (monkeys, cats)
P01HL12738-10 0108 Physiologic pharmacology and its
clinical applications ■ Developmental electrophysiology and
pharmacology (human, animals)
POlHL-1273810 0127 Physiologic pharmacology and Its
clinical applications - Cardiac electrical activity (human,
animals)
P01HL12738-10 0132
clinical applications
(dogs)
P01HL1273810 0135
clinical applications
(rats, chick embryo)
'* ROlHL-12774-08 Ionic coupling in activation of cardiac
muscle (frogs, guinea pigs)
R01HL13306-08 Pharmacological control of cardiac
membrane currents (cattle, rabbits)
R01HL13339-08 Pharmacology of developing cardiac
tissues (chick embryo)
** R01HL13375-09 Cellular potential changes causing
cardiac arrhythmias (dogs)
R01HL1366606 Pharmacology of genesis of cardiac
rhythmicity (rats, cats)
P01HL14414-07 0014 Environmental influences on
cardiorespiratory and cellular functions ■ Temperature and
acid-base status in tissues, cells, and subcellular system
ROlHL-14483-08 Energy conservation in heart
mitochondria (cattle, E coll, human)
ROlHL-1452307 Generation and regulation of force in
smooth muscle (animals)
P01HL-i4985-07 0012 Adaptation to hypoxia • Direct
effect of hypoxia on pulmcnary vascular smooth muscle
(rats, dogs)
P50HL-1 506 1-07 0005 Response of lung to injury - Airway
smooth muscle In health and disease (dogs, guinea pigs)
Physiologic pharmacology and its
Coronary occlusions and arrhythmias
Physiologic pharmacology and Its
Myocardial cells in tissue culture
Electrophysiology of cardiac automaticlty
Vagal control of heart rate-A biophysical
P60HL-15162-07 0020 Comprehensive sickle cell center -
Biophysical studies of normal and sickle red cells (human)
POlHL-15835-06 0013 Study of muscles related to heart
disease - Cardiac bioenergetics (rats)
POlHL-15835-06 0019 Study of muscles related to heart
disease - Vascular smooth muscle-Electron microscopy,
excitation contraction (animal)
POIHL 16117-05 0004 Ion movements and membranes In
cardiovascular control - Optical studies of excitation-
contraction coupling (frogs, snakes)
£01HL-16135-0S Mechanisms of cardiac autorhythmiclty
(dogs, bats)
ROlHL-16328-06 Membrane electrical properties of
vascular muscle (human, animals)
ROlHL-16454-03 Vascular muscle reactivity in
hypertension (human, rats)
ROlHL-17555-05 Distribution and metabolism of labeled
digitaloids (dogs, guinea pigs)
P50HL-17648-04 0014 Study of ischemic heart disease -
Antldysrhythmic drugs and mammalian cardiac Purkinje
fibers (sheep, dog)
P50HL-17648-04 0028 Study of ischemic heart disease -
Electrophysiology of sympathetic innervation in tissue
culture
ROlHL-17702-04 Electro-optical dyes as probes of heart
excitability
ROlHL-19045-03
(human, dogs)
' R01HL-I9076-03
model (rabbits)
ROlHL-192 16-03 Characterization of cardiac pacemaker
activity (cat. dog. rabbit)
POlHL-19242-02 0003 Study of vascular smooth muscle ■
Vasoactive metabolites from vascular muscle and
parenchymal tissue (animal)
P01HL1924202 0009 Study of vascular smooth muscle -
Electrophysiology of vascular smooth muscle (rats, chick
embryo)
ROlHL-19639-02 Permeability transients of carriers.
channels and heart
ROlHL-19673-03 Surgical aspects of shock and hypo.<ia
(dogs, monkeys, rats)
POlHL-19737-02 0002 Cellular and molecular aspects of
respiratory physiology - Airway smooth muscle in health
and disease (human, animals)
ROlHL-19848-02 Contractile activation by rapid
temperature jumps (frogs)
ROIHL- 19995-02 Sensory transduction in cardiac
mechanoreceptors (cats, frogs, rats)
ROlHL-201 53-02 Intracellular pH and myocardial
electropharmacology (dogs, guinea pigs)
ROIHL 20230-02 Analysis of the action potential of
cardiac muscle (sheep)
* ROlHL-20254-02
Fluorescent dyes
ROlHL-202 73-02
complex (dogs)
ROlHL-20708-02 Voltage clamp of embryonic heart cell
aggregates (rat and chick embryos)
ROlHL-20725-02 Mechanisms and cellular functions of ion
transport
ROlHL-21099-02 Subcellular changes of blood vessels In
hypertension (rats)
ROlHL-21136-02 Ion activities and transport in cardiac
muscle cells (sheep)
R23HL-21167-02 The electrophysiology of cardiac
hypertrophy (rats)
* ROlHL-21179-01 Volume regulation-Role of the membrane
potential (amphiuma)
R23HL-212 13-01 A mode! for calcium homeostasis in
excitable tissue (marine worms)
ROlHL-212 17-01 Ion and 5-hydroxytiyptamine transport by
platelets
ROlHL-21525-02 Effect of cations, anions and water upon
blood vessels (dogs, rats)
ROlHL-21574-01 Automaticlty of AV node and Its adjacent
tissues (dogs)
ROlHL-21670-Oi Antiarrhythmic studies on 2-substituted
aminoindenes (dogs)
ROlHL-21672-01 Antiarrhythmic drug action on VMAZ of
cardiac cells
ROlHL-21742-01 Frequency dependent drug actions in
cardiac muscle (rabbits)
ROlHL-21922-01 Transient currents induced by
strophanthidin in the heart
ROlHL-22137-02 Structure-function pathology of isolated
heart cells (mice, rats)
ROlHL-22235-01 Mechanism of cardiac pacemaking
(rabbits)
ROiHL-22239-01 The molecular basis of electrical
excitability (chick embryos, rats)
ROlHL-22426-01 Initiation of the heartbeat -A voltage-
clamp study (bullfrogs, rabbits)
ROlHL-22562-02 Mechanism of cardiac action potential
propagation (tunicates)
ROlHL-22767-01 Model system for cardiac action
potentials (squid, axons)
ROlHL-230 13-01 Smooth muscle development In vitro
(chick embryo)
Probes of heart and nerve membranes-
Cardiac fiber direction and the QRS
ROlHL-231 83-01
membranes
Voltage dependent conductance in
ELECTROPOTENTIALS, SLOW POTENTIALS
POlHL-08682-15 0037 Regulation of the cardiovascular
system - Central nervous regulation of cardiopulmonary
mechanisms (cats)
ROlHL-17907-04 Brain regulation of cardiac arrhythmia
(pigs, cats, rats)
POlHL-19242-02 0009 Study of vascular smooth muscle -
Electrophysiology of vascular smooth muscle (rats, chick
embryo)
ELECTROPOTENTIALS, SPIKE POTENTIAL
ROlHL-15659-05 Dynamic isolation studies of control of
respiration (human)
ROlHL-22418-01 Neural control of cardio-respiratory
function (cats)
ELECTROPOTENTIALS, ZETA POTENTIAL
SEE ALSO ELECTROPOTENTIALS. MEMBRANE POTENTIALS
P50HL-14147-08 0014 Specialized center of research in
thrombosis - Theoretical models for electrostatic effects in
blood clot formation
P50HL-14147-08 0015 Specialized center of research in
thrombosis ■ Charge related properties of phospholipid
surfaces in monolayers and vesicles
ROlHL-14271-07 Physiccchemical properties of tracheal
mucus (dogs, frogs)
R01HL-1692I-05 Synthetic hydrogels as blood tolerable
materials
ROlHL-20365-03 Molecular mechanisms of anion transport
ELECTRORETINOGRAPHY
SEE EYE DISORDERS DIAGNOSIS, RETINOGRAPHY.
ELECTRORETINOGRAPHY*
ELECTROSTIMULUS
SEE ALSO ELECTRONIC STIMUUTORS (GENERAL)
** POIHL 06308 18 0037 Mechanisms and therapy of
circulatory disease - Electrophysiology, blood flow, and ANS
in ventricular fibrillation (dogs)
** POlHL-06308-18 0038 Mechanisms and therapy of
circulatory disease - Electrophysiology of ventricuair
arrhythmias associated with ischemia (dogs)
POlHL-06835 17 0060 Cardiovascular disease -
Ventricular performance experimental models of arterial
hypertension (rats, dogs)
ROlHL-08359-14 Morphopharmacology of vascular
adrenergic transmission (rabbits, rats)
POlHL-08682-15 0033 Regulation of the cardiovascular
system - Functional and anatomical relations during
cardiac re-innervation (dog)
POlHL-08805-15 0046 Regulation of ventilation and
pulmonary circulation - Sites and modes of interaction of
peripheral and central chemoreceptors
POlHL-11678-11 0031 Cardiovascular dynamics and their
control - Hypertension caused by stimulation of renal
sympathetic nerves (dogs)
POlHL-11678-11 0069 Cardiovascular dynamics and their
control - Nervous control of the cirulation (dogs)
POlHL-14388-07 0183 Regulation of the circulation in
pathological states - Vasopressin in cardiovascular
regulation (dogs, rats)
POlHL-14388-07 0203 Regulation of the circulation in
pathological states - Activation of sympathetic nervous
systems in spontaneously hyperactive rats
ROlHL-14614-07 Voltage control of contraction in heart
(sheep)
ROlHL-15805-06 Cerebral arterial tone and reactivity
(rabbits)
POlHL-16137-05 0013 Alveolar biology - Development and
pathology of surfactant-Formation of alveolar (rabbits,
sheep)
POlHL-19242-02 0007 Study of vascular smooth muscle -
NE release in and reactivity of vascular smooth muscle
(animals)
ROlHL-20273-02 Cardiac fiber direction and the QRS
complex (dogs)
R23HL-21042-01 Cardiopulmonary reflexes and their
anatomical basis (dogs)
ROlHL-21187-01 Potassium, norepinephrine, and coronary
arterial tone (dogs)
ROIHL 21436-02 Autonomic control of renal function
(cats)
ROlHL-21570-01 The mechanical basis of myocardial
energetics (cats)
POlHL-21584-02 0005 Respiratory mechanics in normal
and abnormal states - Regulation and behavior of airway
smooth muscle (human, animals)
ROlHL-22239-01 The molecular basis of electrical
excitability (chick embryos, rats)
** ROlHL-22425-01 Initiation of the heartbeat -A voltage-
clamp study (bullfrogs, rabbits)
ROlHL-22484-01 Neural control of cardiac conduction and
excitation (dogs)
ROlHL-22715-01
reflexes (dogs))
ROlHL-22732-01 Central organization of cardiac afferent
nerves (cats, monkeys)
R23HL-22747-01 Cardiodynamics and hypertension under
cerebellar control (dogs)
ROlHL-22910-01 Control of breathing pattern in health
and disease (human, animals)
R23HL-22920-01 Dynamic airway behavior (dogs)
(contd)
Neural integration of the cardiovascular
'Excludes routine methodology OR covers only general projects which preclude Indexing at the specific level.
''Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
I
EU
199
tND
R23HL 17917 01 MlCfsciiculntory lunrtion in liypotanilon
((•ll. himsteri)
ROIHL ?3?0I 01 Mfchanisms ol hypeitanslon (hiiman.
rats)
ROIHL ?39llb 01 Rola ot tlia dliphraim In ra|lonal lung
mechanics ldo|s)
ELECTROTHERAPY
SEE HEALTH CARE SERVICES. PHYSICAL THLRAPY.
ElfCIROTHERAPY
ELECTROVALENT BONDS
SEE CHEMICAL BONOS, IONIC
ELEMENTS, TRACE
SEE CHEMICALS (GENERAL). ELEMENTS. TRACE ELEMENTS
ELUPTOCYTOSIS HEREDITARY
SEE BIOOO AND RE DISORDERS. ANEMIA HEMOIYTIC
CONGENITAL. ELLIPTOCYTOSIS HEREDITARY
EMBDEN-MEYERHOF PATHWAY
SEE HEXOSES. GLYCOLYSIS ANAEROBIC, EM PATHWAY
EMBOUSM
SEE CARDIOVASCUUR DISORDERS. EMBOLISM
EMBOUSM (AIR)
SEE CARDIOVASCULAR DISORDERS, EMBOLISM, AIR
EMBOLISM (FAT)
SEE CARDIOVASCUUR DISORDERS, EMBOLISM, FAT
EMBOLIZATION THERAPEUTIC
SEE CARDIOVASCULAR SURGERY, VASCULAR OCCLUSION
THERAPEUTIC
EMBRYO, MAAAMAUAN
SEE PREGNANCY. EMBRYO-FETUS
EMBRYO CHEMOTHERAPY, MAMMALIAN
SEE PREGNANCY, EMBRYO-FETUS CHEMOTHERAPY
EMBRYO-FETAL DISORDERS (GENERAL)
SEE PREGNANCY DISORDERS, EMBRYO-FnAL DISORDERS
(GENERAL)
EMBRYO-FETUS DRUGS ADVERSE EFFECT
SEE PREGNANCY, EMBRYO-FETUS DRUGS ADVERSE EFFECTS
EMBRYO-FETAL GROWTH-DEVELOPMENT
DISORDERS
SEE PREGNANCY DISORDERS, EMBRYOFnAL GROWTH-
DEVELOPMENT DISORDERS (SEE ALSO APPROPRIATE
SPECIFICS)
EMBRYO-FETUS PHARMACOLOGY
SEE . SEGNANCY, EMBRYO-FETUS PHARMACOLOGY
EMBRYO RESORPTION
SEE PREGNANCY LOSS, FETAL DEATH
EMBRYO SURGERY, MAMMAUAN
SEE PREGNANCY, EMBRYO-FETUS SURGERY
EMBRYO TRANSFER, MAAAAAALIAN
SEE PREGNANCY, EMBRYO-FETUS TRANSPUNTATION
EMBRYO TRANSPLANTATION, MAMMALIAN
SEE PREGNANCY, EMBRYO-FETUS TRANSPLANTATION
EMBRYOLOGY
SEE ALSO CARDIOVASCULAR SYSTEM, DUCTUS ARTERIOSUS
EMBRYONIC
SEE ALSO HEART, FORAMEN OVALE EMBRYONIC
SEE ALSO PREGNANCY
POlHL-06314-17 0054 Immunologic mechanisms In
cardiovascular disease - Physiology of cell communications
(mice, frogs, guinea pigs)
ROlHL-07047-16 Comparative study of cardiac conduction
system (human, birds, mammals)
ROlHL-13339-08 Pharmacology of developing cardiac
tissues (chick embryo)
R01HL-1383i-08 Factors regulating embiyonic cardiac
morphogenesis (chick, salamandra)
R01HL-1390I-08 Ontogeny, ultrastructure, function in
lymphatic system (birds, fish, mammals)
** ROlHL-16152-06 Electrophysiology uf neonatal io adult
heart (cats, frogs, guinea pigs)
** ROlHL-16567-04 Differentiation of the heart-cell
membrane (mice, chick)
** ROlHL-17367-05 Functional sympathetic development in
neonatal hearts (dogs, human)
ROlHL-1 7581-03 Patent ductus arteriosus and pulmonary
hypertension (dogs)
ROlHL-18050-04 Mechanisms of cardiovascular
tcratogenesis (chick embryo) k embryo)
ROlHL-18711-03 Electrophysiology of heart cells (rats,
chicks)
** ROlHL-18714-04 Cardiovascular matrix-Morphogenesis
and maturation (human, chick embryo, mammal)
ROlHl-18848-03 Etiology and development of congenital
heart disease (dogs, cats)
** ROlHL-19068-03 Changes in membrane properties during
erythropolesis (chick embryo)
ROlHL-22226-01 Autonomic nervous elements in the
developing heart (rabbits)
RUlHl??ib0 0?
and hainstflrs
ROIHL 24048 01
rhick plnhlYo^
Genalic cardliimyopalMies in lalamandars
KeRiil/itiun ul ItRmoglobin synthosii in
EMBRYOLOGY (HUMAN) AND DEVELOPMENT
STUDY SECTION
F«lal and neonatal caidlovascular
Fetal and naonaltl pulmoniry circulation
ROIHL 0W55 2S
function (sheep)
ROIHL 10834 09
(toats)
ROIHL 15341 06 Lung hormonal and chromosomal
regulation (rats, rabbits)
ROIHL 156SS05 Blood How and gas exchange in placenta
and lungs (sheep) rabbits)
ROIHL 1/36705 Functional sympathetic development in
neonatal hearts (dogs, human)
ROIHL 1913603 Mucopolysaccharide metabolism in
cardiac anomalies (rats)
ROlHL'19430-03 Congenital heart malformations and
situs inversus (mice)
ROIHL 20337 02 Thromboembolic diseases (human)
ROIHL 20635 03 Factors in lung development (rat and
chick embryo)
R23HL 21405 01 Respiratory muscles in regulation of
infant breathing (human)
R23HL 21409-02 Perinatal control of the ductus arteriosus
(sheep)
ROlHL-22226 01 Autonomic nervous elements in the
developing heart (rabbits)
ROIHL 2250001 Conversion of choline to
phosphatidylcholine in lung (rabbits, pigs)
ROlHL-22859-01 Effect ot carbon monoxide on the
developing heart (rats)
EMBRYONIC CELL LINES
SEE TISSUE (CELL) CULTURE, EMBRYONIC-FETAL CELL LINES
EMBRYONIC NEOPLASMS
SEE NEOPLASMS, EMBRYONIC
EMBRYOPATHY
SEE PREGNANCY DISORDERS, EMBRYO-FETAL DISORDERS
(GENERAL)
EMERGENCY CARE
SEE HEALTH CARE SERVICES. PATIENT CARE, EMERGENCY
CARE
EMERGENCY SERVICES
SEE HEALTH CARE SERVICES, PATIENT CARE, EMERGENCY
CARE
EMESIS
SEE GASTROINTESTINAL DISORDERS. EMESIS
EMI SCAN
SEE RADIOGRAPHY, SCANNING, CAT*
EMISSION SPECTROGRAPH (LASER PROBE)
SEE CHEMISTRY. ANALYTICAL METHODS, SPECTROMETRY,
LASER*
EMOTIONAL ADJUSTMENT
SEE PSYCHOLOGICAL ADAPTATION, EMOTIONAL ADJUSTMENT
EMOTIONAL DEPENDENCY-INDEPENDENCY
SEE PSYCHOLOGY, EMOTIONAL DEPENDENCY-INDEPENDENCY
EMOTIONAL DISORDERS
SEE PSYCHOLOGY ABNORMAL, EMOTIONAL DISORDERS
EMOTIONAL STRESS
SEE PSYCHOLOGIC STRESS
EMOTIONS
SEE PSYCHOLOGY, EMOTIONS
EMPATHY
SEE PSYCHOLOGY, EMOTIONS, EMPATHY
EMPHYSEMA, PULMONARY
SEE RESPIRATORY DISORDERS. BRONCHITIS CHRONIC AND
EMPHYSEMA
EMPLOYMENT
SEE OCCUPATIONS, EMPLOYMENT
EMULSIONS
SEE PHYSICAL PROPERTIES, EMULSIONS
EMULSIONS (DOSAGE FORM)
SEE DOSAGE FORMS
ENDARTECTOMY
SEE CARDIOVASCULAR SURGERY, BLOOD VESSELS
RESTORATION. ENDARTECTOMY
ENDOCARDIAL FIBROELASTOSIS
SEE HEART DISORDERS, ENDOCARDIAL FIBROELASTOSIS
ENDOCARDITIS BACTERIAL
SEE HEART DISORDERS. ENDOCARDITIS BACTERIAL
ENDOCARDIUM
SEE HEART. ENDOCARDIUM
ENDOCRINE DISORDERS
SEE ENDOCRINOLOGY, ENDOCRINE DISORDERS
*Excludes routine methodokigy OR covers only general projects which preclude indexing
"Oriented significantly to above subject.
ENDOCRINE OlSOROEitS CHCMOTHERAPY
SI I INDOI.RINOIOI.Y, INljrjr.RINI l)l".()«()l K',
I MIMIJIHIHAI'Y
ENDOCRINE DISORDERS DIAGNOSIS
Sff INDOCHINOinC.Y. INDOCRINF DCOKDEHS DIAGNOSIS
ENDOCRINE GLANDS
Sff tNDO(,RINOlOGY. INDOCRINfS
ENDOCRINE GLANDS DISORDERS
SIF (NOOCHINOIOGY. fNOOCRINI DI'.fjRUrR";
ENDOCRINE GLANDS NEOPLASMS
Sir NFOPIASMS Of ENDOr.RINfS
ENDOCRINE GLANDS TRANSPLANTATION
SEE ENDOCRINOLOGY. ENDOCRINE TRAHSPLANTAIION
ENDOCRINE PHARAAACOLOGY
SEE ALSO ENDOCRINOLOGY, ENDOCRINE DISORDERS
CHEMOTHERAPY
ROIHL 10567 1? Erythropoietin Immunoassay and
characterization (dogs)
R01HI-12G85 10 Lipoprotein carbohydrate metabolism
(human, rats)
ROlHl-12557-09 Effects of steroids and pregnancy on
arteries and veins (guinea pigs)
ROIHL-18148-04 Adrenal catecholamine secretion
P50HL 18323 04 0037 SCOR hypertension center
Adrenocortical factors in childhood hypertension
ROIHL 1873003 Role of mineralocorticoids in low renin
hypertension (human, rats)
ROlHL-18893-03 Mechanism of angiotensin action-Role of
receptor (rats)
ROIHL 19115-02 Hormonal control of tracheobronchial
cyclic AMP (rats, guinea pigs)
ROlHL-19644 03 Etiological factors in hypertension
(human, dogs, rats)
R0IHL-I9898-O3 Desferrioxarnine therapy in thalassemia
(dogs, rats, children)
ENDOCRINE REGULATION AND CONTROL
(MECHANISMS)
SEE ENDOCRINOLOGY, HORMONAL REGULATION AND
CONTROL (MECHANISMS)
ENDOCRINOLOGY (GENERAL)
POlHL-11678-11 0046 Cardiovascular dynamics and their
control Regulation of aldosterone secretion and related
factors (dogs)
ENDOCRINOLOGY, ENDOCRINES
SEE ALSO ADRENAL GLANDS
SEE ALSO NERVOUS SYSTEM, PARAGANGLIA
SEE ALSO NEUROENDOCRINE SYSTEMS
SEE ALSO PITUITARY-DIENCEPHALON (HORMONES)
SEE ALSO PITUITARY GLAND
SEE ALSO REPRODUCTIVE SYSTEM, GONADS
POlHL-11678-11 0017 Cardiovascular dynamics and their
control - Overall control of circulation-Mathematical
analyses
ENDOCRINOLOGY, ENDOCRINE DISORDERS
SEE ALSO ADRENAL GLANDS DISORDERS
SEE ALSO CARBOHYDRATES METABOLISM DISORDERS,
DIABETES
SEE ALSO DISEASES, SIGNS-SYMPTOMS, HIRSUTISM
SEE ALSO METABOLIC DISORDERS (INBORN). DIABETES
INSIPIDUS
SEE ALSO PANCREATIC ISLETS DISORDERS
SEE ALSO REPRODUCTIVE AND SEX DEVELOPMENT
DISORDERS
SEE ALSO SKELETAL DISORDERS, BONE DEVELOPMENT,
DWARFISM, PITUITARY
SEE ALSO THYROID GLAND DISORDERS
POlHL-06835-17 0021 Cardiovascular disease - Animal
study in atherosclerosis (dog, guinea pig)
ROlHL-06924-16 Humoral and metabolic aspects of
cardiac function (mammals, non-human, human)
ROlHL-18938-03 Pulmonary fatty acid and phospholipid
metabolism (rats)
R01HL-19175-03 Pituitary modulation of micro-and macro-
vascular disease (human, rats)
ROlHL-19195-03 Hormonal regulation ol lung function
(rats)
ROlHL-19898-03 Desferrioxamine therapy in thalassemia
(dogs, rats, children)
ENDOCRINOLOGY, ENDOCRINE DISORDERS
CHEMOTHERAPY
SEE ALSO ENDOCRINE PHARMACOLOGY
POlHL-06835-17 0050 Cardiovascular disease - 18-
Hydroxylase block in the 17 alpha-hydroxylase deficiency
syndrome (human)
ROlHL-13632-08 Vascular changes in diabetes mellitus
(human)
ROIHL 17749-03 Adrenocortical factors in human
hypertension (human)
POlHL-18574-03 0006 Lipoprotein methodology and
biomedical applications - Lipoprotein transformation,
lipolytic enzymes, diet and lipid lowering agents
ROlHL-18579-03 Vasoactive hormones and blood pressure
regulation (dogs, rats, rabbits)
(contd)
at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
END
196
END
ENDOCRINOLOGY, ENDOCRINE DISORDERS
DIAGNOSIS
SEE ALSO THYROID FUNCTION
ROIHL-1 1046-12 Renin, angiotensin, steroids. Ions and
blood pressure (human, sheep, rabbits)
P50HL-14192-08 0007 Specialized center of research in
hypertension - Role of new mineralocorticoids in
hypertension (human, rats)
*• R01HL17749-03 Adrenocortical factors In human
hypertension (human)
ROlHL'19961-03 Management of hemosiderosis in
thalassemia (children, adults)
ENDOCRINOLOGY, ENDOCRINE SURGERY
SEE ADRENALECTOMY
SEE BLOOD AND RE SYSTEM, THYMECTOMY
SEE ENDOCRINOLOGY, ENDOCRINE TRANSPLANTATION
SEE PARATHYROIDECTOMY
SEE PITUITARY REMOVAL
ENDOCRINOLOGY, ENDOCRINE
TRANSPLANTATION
R01HL-13408-05 Environmental-genetic interactions in
hypertension (rats)
ENDOCRINOLOGY, HORMONAL REGULATION
AND CONTROL (MECHANISMS)
** ROlHL-01813-25 Regulation of metabolism by drugs and
hormones (rats)
ROlHL-02033-23 Regulation of cholesterol esters In blood
and tissues (rat, cattle, human)
R01HL-020e3-23 Biochemistry and function of lipids and
cell membranes (human, yeast, animals)
R01HL-0S360-19 Cholesterol biosynthesis and Its control
In liver (rats)
** P01HL-06285-18 0193 Cardiovascular-respiratory
physiology and biochemistry - Hormonal regulation of
sodium transport-Aldosterone (rats, toads)
** P01HL-06285-18 0194 Cardiovascular-respiratory
physiology and biochemistry Hormonal regulation of
sodium transport-RNA synthesis (rats, toads)
" POlHL-06285-18 0195 Cardiovascular-respiratory
physiology and biochemistry - Thyroid thermogenesis and
sodium transport (rats)
** POlHL-06285-18 0196 Cardiovascular-respiratory
physiology and biochemistry - Hormonal regulation of
sodium transport -Epithelial cell membranes (toads)
POlHL-06285-18 0200 Cardiovascular-respiratory
physiology and biochemistry - Medullary counter-current
system (animals)
POlHL-06296-18 0005 Cardiovascular and pulmonary
adaptation to stress - Regulation of ventricular
performance (animals)
R01HL-06924-16 Humoral and metabolic aspects of
cardiac function (mammals, non-human, human)
P01HL-08682-15 0019 Regulation of the cardiovascular
system - Hepatic immunophyslology and host-defense In
shock (rat, dog, human)
POlHL-08682-15 0020 Regulation of the cardiovascular
system - Hepatic metabolic basis of shock (rat)
ROlHL-08893-14 Structure and function of membrane
proteins (human)
** ROlHL-09154-14 Central control of distribution of organ
blood flow (monkeys)
ROlHL-09911-12 Hormonal and dietary modification of
NaCl toxicity (rats) mice)
ROlHL-09921-13 Mechanisms related to congestive heart
failure (dogs, human, rat)
** R01HL-10612-13 0021 Humoral factors In heart failure
and hypertension - The control of aldosterone secretion
(dogs)
** ROlHL-1 155 1-11 RNA and protein synthesis in repair of
heart injury (mice, rats)
POlHL-1 1678-11 0027 Cardiovascular dynamics and their
control - Vasopressin and thirst in control of body fluid
volumes and osmolality (dogs)
** POlHL-11678-11 0047 Cardiovascular dynamics and their
control - Unidentified pituitary factor In regulation of
aldosterone secretion (rats)
R01HL-1190M2 0014 Effects of metabolic surgery on
the hyperllpidemias - Effect of bypass on gastrin levels
(dogs, human)
** ROIHL 12085-10 Lipoproteln-carbohydrate metabolism
(human, rats)
POlHL-12373-10 0005 Cardiopulmonary physiology and
pathophysiology - Characterization of fetal and neonatal
myocardium (human, cats)
POlHL-12373-10 0006 Cardiopulmonary physiology and
pathophysiology - Fatty acid metabolism -Regulation,
implications (human, mammals, birds)
** ROlHL-12677-10 Surgical physiologic studies of isolated
kidneys (dogs, rats)
** ROlHL-12990-09 Control of antidiuretic hormone secretion
and metabolism (dogs, rats, rabbits)
ROlHL-13302-09 Uptake and metabolism of lipids by the
Regulation of lipid metabolism in the
liver (rats)
ROlHL-13405-09
lung (rats)
ROlHL-13626-06 Lipoprotein lipase and lipoprotein
removal (human, rats, bacteria)
ROlHL-13630-08 Control of glycogen synthesis In heart
(cattle)
Regulation of the circulation In
Vasopressin In cardiovascular
ROlHL-13694-08 Capillary basement membrane in
cardiovascular disease (human, rats)
ROlHL-1384116 Respiration during altitude
acclimatization (goats, dogs, rats, rabbits)
P50HL- 141 59-08 0008 Specialized center of research in
hypertension - Renal function and sodium metabolism in
hypertension (rats, human, rabbits)
P50HL-14192-08 0007 Specialized center of research In
hypertension ■ Role of new mineralocorticoids In
hypertension (human, rats)
P50HL-142 14-07 0015 Newborn lung center for hyaline
membrane disease - Hormone effect on cyclic nucleotide
lipid synthesis in developing lung (animal)
P50HL-1421407 0021 Newborn lung center for hyaline
membrane disease - Development of surfactant system-
Surfactant production and release (rat, rabbit)
P50HL-142 14-07 0024 Newborn lung center for hyaline
membrane disease - Synthesis and receptors for ACTH In
fetal lung (human)
P01HL1438807 0179 Regulation of the circulation In
pathological states Cultured muscle cells and their cross-
Innervatlon In vitro (rats, sheep)
POlHL-14388-07 0180 Regulation of the circulation In
pathological states - Regulation of cerebral blood flow
(dogs, monkeys)
POIHL 14388-07 0183
pathological states
regulation (dogs, rats)
POIHL- 143 88-07 0191 Regulation of the circulation in
pathological states - Regulation of chloride transport in
epithelial membranes (turtles)
POlHL-14388-07 0193 Regulation of the circulation In
pathological states - Ontogenesis of central nervous system
amines in hypertension (rats)
ROlHL-14990-07 Lipid transport in avian species
(chickens)
ROlHL-15427-06 Secretion of plasma lipoproteins (rats)
ROlHL-15646-03 Lipid studies in vascular smooth muscle
cells (human, monkeys)
ROlHL-15685-05 Hemopoietic regulators produced In cell
culture (human, animals)
' ROlHL-15930-06 Hormonal control of lipid and lipoprotein
synthesis (rats)
' ROlHL-15985-06 Metabolic and hormonal control of
cardiac contraction
* P60HL- 16005-05 0013 Comprehensive sickle cell center -
Study of regulation of erythropoiesis in vitro (human, rat.
hamster, rabbit)
ROlHL-16037-06 Molecular properties of cardiac
adrenergic receptors
* ROlHL-16364-04 Regulation of lipid biosynthesis and
transport (rats, swine, Xenopus)
' POlHL-16387-04 0009 The blood vessel and
thrombogenesis - Role of pituitary gland in the
pathogenesis of arteriosclerotic lesions (rats)
ROIHL 16512-04 Lipoprotein metabolism and hormonal
regulation (chickens)
ROlHL-16577-04 Lipoprotein lipase chemistry and function
(rats, cattle, human)
ROIHL- 179 58-04 Circulatory effects of operant
cardiovascular control (baboons)
ROlHL-17976-18
enzymes (sheep)
Chemical agents and heart glycolytic
Human dopamlne-beta-hydroxylase (also
R01HL-18095-04
cattle)
ROIHL 18176-02 Effect of thyroid hormone on cultured
cardiac cells (rats)
ROlHL-18185-04 Cardiac glycosides and diuretics-Role of
NaO pump (dogs)
ROlHL-18260-04 Cyclic nucleotide metabolism in lung
tissue (cattle)
P50HL-183 18-03 0007 Pathogenesis and complications of
hypertension - Humoral factors and renal function In
experimental hypertension (rats)
ROlHL-18567-03 A routine diagnostic test for minimal
heart damage (human, rat)
POlHL-18645-03 0007 Biology of the arteiv wall and
atherosclerosis - Lipoprotein metabolism in subhuman
primates
ROlHL-1870503 Regulation of plasma triglyceride
metabolism (rats)
ROlHL-18723-03 Genetic heterogeneity of acid lipase-
Atherosclerosis (human)
ROlHL-18938-03 Pulmonary fatty acid and phospholipid
metabolism (rats)
ROlHL-18948-03 Pulseless flow and circulatory assistance
(dogs, calves)
ROlHL-18952-03 Metabolism in perfused fetal and
newborn rabbit lungs
ROIHL- 189 95-04 Cardiovascular determinants of
catecholamine release (dogs)
ROlHL-19063-03 Cholesterol and lipoprotein metabolism
(rat hepatocytes)
ROIHL 19068-03 Changes in membrane properties during
erythropoiesis (chick embryo)
ROlHL-191 15-02 Hormonal control of tracheobronchial
cyclic AMP (rats, guinea pigs)
P50HL-19160-02 0001 Mucus abnormality in cystic
fibrosis - Regulation of respiratory secretions (rat, human)
P50HL-1916002 0002 Mucus abnormality in cystic
fibrosis - Ultrastructure, cytochemistry of pulmonary
secretion (human, rat)
ROlHL-19175-03 Pituitary modulation of micro-and macro-
vascular disease (human, rats)
ROlHL-19181-02 Regulation of heart cAMP-dependent
protein kinase (rodents)
ROlHL-19195-03 Hormonal regulation of lung function
(rats)
ROlHL-19223-03 Control of cholesterogenesis in leukocytes
and liver (rats, human)
ROlHL-19322-03 Role of pituitary hormones in the action
of vitamin K (rats)
P50HL-19362-02 0002 A/S SCOR -Atherosclerosis in
nonhuman primates - Infant caloric intake, adipose tissue
development and atherosclerosis (baboon)
ROlHL-19366-03 Renal Starling forces in experimental
conditions (rats, rabbits)
ROlHL-19379-03 Characterization of small-granule cells in
the lung (mammals)
ROlHL-19394-03 Biochemistry and regulation of taurine in
the heart (rats, guinea pigs, cats)
R01HL-19644-03 Etiological factors in hypertension
(human, dogs, rats)
ROIHL- 19669-03 Lung organ culture and surfactant
biosynthesis (adult and fetal rats)
ROlHL-19684-03 Histotypic lung culture in circumfusion
systems (mice)
ROlHL-19752-03 Phospholipid synthesis by fetal lung in
organ culture (rats)
ROlHL-20061-02 Serum lipoproteins and cell cholesterol
metabolism (rats, human)
ROlHL-2019702 Maintenance and repair of vascular
endothelium (human, animals)
ROlHL-20339-02 Vascular alpha-adrenergic receptor
molecular properties
ROlHL-20364-01 Episodic hypertension associated with
human behavior (air traffic controllers)
ROlHL-20476-03 Effects of diabetes on cardiac
performance (rat)
ROlHL-20517-03 Diabetes, somatotropin, factor VIII and
atherosclerosis (human, animal)
ROlHL-20859-02 Beta adrenergic catecholamine receptor
ROlHL-20905-02 Synthesis of fetal hemoglobin in erythroid
cells (sheep, human)
ROlHL-20912-02
thassemic mice
ROlHL-2092202
synthesis
ROlHL-20939-02
humans
R23HL-21 189-01 Regulation of pulmonary endothelial cell
activities (human, cattle)
ROlHL-21799-01 Circumventricular sites of pressor action
of angiotensin II (rats)
ROlHL-2 1800-01
excretion
R01HL-2205I-01
release (human)
* ROlHL-22053-02 The disordered lipid metabolism of
diabetes mellltus (chickens, mammals, human)
ROlHL-22069-02 Experimental renal arterial hypertension
(dogs)
ROlHL-22088-02 Metabolic basis for diabetic
microangiopathy (cattle)
ROlHL-22101-02 Hormone-substrate Interaction in diabetic
myocyte (dogs, rats)
R01HL-2213e-02 Histamine and cardiac adenyl cyclase
ROlHL-22219-01 Prostacyclin and peroxides in blood and
membrane disease
* ROlHL-22225-01 Hormonal regulation of blood pressure
and blood flow (human, animals)
ROlHL-22264-01 Regulation of contraction in vascular
smooth muscle (dogs)
ROlHL-22306-01 Renal catecholamines- Pathophysiology
of hypertension (dogs)
ROlHL-22361-01
exercise (rats)
ROlHL-22444-01
culture (human)
R23HL-22490-01
heart cells
* ROlHL-22561-01
circulation (cats)
ROlHL-22569-02
Control on non-alpha chain synthesis in
Control of human fetal hemoglobin
Regulation of fetal hemoglobin In
Angiotensin effects on water intake and
Role of angiotensin II in vasopressin
Regulation of cardiac adaptation to
Bronchial mucus production in organ
Neurotransmitter receptors of cultured
Hormonal control of mesenteric
Intestinal secretion-Capillary and tissue
forces (dogs, cats)
ROlHL-22729-01 Intracellular degradation of newly
synthesized collagen (human, chick, rabbit)
ROlHL-22812-01 Regulation of hepatic production of HDL
(rats)
** ROlHL-2287301 Adrenoceptor interconversion and
hormone homeostasis
ROlHL-231 15-01 Regulation of active sodium transport
(frogs, rats)
ROlHL-23587-01
(guinea pigs)
ROlHL-23604-01
mechanisms (rat)
ROlHL-23618-01 Substrate metabolism in isolated
myocytes in shock (dogs. rats, guinea pigs)
ROlHL-23990-01 Role of phosphoprotein in cardiac
inotropic responses
ENDOCRINOLOGY, HORMONE BINDING
PROTEINS
SEE ALSO GLOBULINS, CORTICOSTEROID BINDING GLOBULIN
(contd)
Phosphorylation of myocardial protein
Hepatic microvascular regulatory
•Excludes routine methodotogy OR covers only general projects which preclude indexing at the specific level.
**Onented significantly to above subject-
M Grant has subpiojects describing specific research aspects.
See Appendix for investigator's name and grant number.
END
197
END
SK ALSO HALOPROTtlNS, THYROXINf BINDING PROTFINS
" ROIHI 02063 23 8ioch«iiii<itry anil lunction ot lipids ind
ctit mtmbiants (human, y«asl. animals)
POIHL 06285 18 0193 CaidiovaKulai lespiiatoiy
physiology and biochannslfy Noimonal ifnulation ol
sodium tianspoit Aldoslaion« dais, toads)
ROIHL llSSl II RNA and piolein synlhosis in icpaii ol
haait iniuiy (mic«. lals)
** ROIHI 16SI2 04 Lipoprotein metabolism and hormonal
regulation (chickens)
ROIHL 19279 03 Intiacellulai action ol aldosterone in
hypertension (human, rats)
ROIHL 1964403 etiological factors in hypertension
(human, dogs, rats)
ROIHL 2064S 01 Etiology ol myacardlal inlaction (human)
ROIHL 23603 01 Morphogenesis ol hypertensive vascular
disease (rats)
ENDOCRINOIOGY, HORMONE RECEPTORS
ROIHL 02063 23 Biochemistry and lunction ol lipids and
cell membianes (human, yeast, animals)
P01HL'0628S 18 0186 Cardiovascular respirator>
physiology and biochemistry Leukocyte hormone receptors
and cyclic nucleotides (tissue culture)
•• P01HL06285 18 0193 Cardiovascular respiratory
physiology and biochemistiY Hormonal regulation of
sodium transport Aldosterone (rats, toads)
P01HL06314 17 0055 Immunologic mechanisms in
cardiovascular disease Genetics and cell biology
ROIHL'08506'15 Lipemia carbohydrate and glyceride
metabolism (human, rats)
ROIHL'11551'11 RNA and protein synthesis in repair of
heart injury (mice, rats)
** POIHL 1273810 0114 Physiologic pharmacology and its
clinical applications - Receptor specificites and metabolism
of neurohypophysial hormones (rats)
ROlHL-137 15-08 Myocardial adenyl cyclase (rats)
P50HL-14159-08 0020 Specialized center of research in
hypertension - Renin mineralocorticoid system in
hypertension (human, rat, dog)
** P50HL1421407 0024 Newborn lung center for hyaline
membrane disease Synthesis and receptors for ACTH in
fetal lung (human)
ROlHL'14509-07 Hypertension-Chemistry and biophysics
of angiotensin
ROlHL-15985-06 Metabolic and hormonal control of
cardiac contraction
ROlHL-16512-04 Lipoprotein metabolism and hormonal
regulation (chickens)
** ROlHL-16918-05 Role of steroids in hypertension (human)
** POlHL-17813-04 0008 Lung disease and the oxygenation
of blooif and tissue - Pulmonary regulation of systemic
blood pressure (human, rabbits, rats)
ROlHL-18181-04 Surfactant metabolism-Alveolar cells and
lung disease (mice, rabbits)
R01HL-18272-03 Heart adenyl cyclase complex (beef
heart)
ROlHL-18730-03 Role of mineralocorticoids in low renin
hypertension (human, rats)
ROlHL-18826-04 Interaction of peptides and target cells
in lung (human)
ROIHL 18893-03
receptor (rats)
ROlHL-19057-03 Catecholamines and cyclic AMP in
cardiovascular system (rats, dogs)
** P50HL-19185-02 0005 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Role and mechanism of
glucocorticoids in fetal lung maturation (human, rabbit)
P50HL-19190-02 0003 Pulmonary SCOR-Pathophysiology,
management of IRDS - Type II cells-Regulation and
differentiation (rat)
ROlHL-19195-03 Hormonal regulation of lung function
(rats)
ROlHL-19279-03 Intracellular action of aldosterone in
hypertension (human, rats)
** ROlHL-20201-01 Hypertension and vascular steroid
receptors (rats)
ROlHL-20544-02 Integrated regulation of myocardial
energy metabolism (rats, guinea pigs)
** ROlHL-22101-02 Hormone-substrate interaction in diabetic
myocyte (dogs, rats)
** ROlHL-22367-01 Estrogen receptors in very low density
lipoproteins (chicken livers)
ROlHL-226 17-01 Angiotensin, hypertension and the CNS
Mechanism of angiotensin action -Role of
(sheep)
ROlHL-22990-01
regulation (rats)
ROlHL-23115-01
(frogs, rats)
Angiotensin II receptors-Mechanisms of
Regulation of active sodium transport
ENDOCRINOLOGY, HORMONES
SEE ALSO ADRENAL CORTEX HORMONES
SEE ALSO ADRENAL MEDULU HORMONES
SEE ALSO ANDROSTANE SERIES. ANDROGENS
SEE ALSO BLOOD AND RE SYSTEM, HEMATOPOIETIC FACTORS
SEE ALSO CELL GROWTH REGUUTION, CHALONES
SEE ALSO ESTRATRIENE SERIES, ESTROGENS
SEE ALSO GASTROINTESTINAL HORMONES
SEE ALSO LIPID MOBILIZING FACTORS
SEE ALSO NERVE GROWTH FACTOR
SEE ALSO NEUROHORMONES
SEE ALSO NEUROTRANSMITTERS (GENERAL)
SEE ALSO PANCREAS HORMONES
SEE Also PARAIIIYROin HORMONrS
SEE At SO PtPIiniS, VASOACMVI PI PIIOES
SEC Also PIUIIIAHYDIINCII'ltAION (HORMONES)
SEl Also (MANIS GKOWIH KIl.DIAIORS
SEE Also PRQCrSlfRONI
SEl ALSO PROCISIINS
SEL ALSO IHYHOIl) HORMONfS
** POIHI 0G3I4 1/ 0052 Immunologic mechanisms in
cardiovascular disease Role ol cyclic nucleotides in
neutrophil function (human)
POIHL 08805 15 004/ Regulation ol ventilation and
pulmonary circulation Extracranial metabolic control ol
ventilation (dogs, goats)
** ROIHL 10897 12 Ellects ol hormones on cardiac
electrogenesis (rabbits, guinea pigs, dogs)
ROIHL 11614 11 Trace elements in nutrition (chickens.
rats, human)
ROIHL 13315 08 Disposition of vasoactive hormones in
mammalian lung (rats, rabbits, human)
ROIHL 14102 07 Human physiology at 5360 meters
Mountain environment
R01HL14706 07 Fetal hearts in organ culture (mice)
ROIHL 16421 08 Determinants of RBC deformability and
capillary flow (human, mice)
** POIHL 17419 04 0006 Studies on mechanisms ol
hemoslasis Elfecl of hormones, drugs and other agents
on fibrinogen synthesis (chick)
ROIHL 18308 03 Comprehensive studies ot mucociliary
transport (dogs)
ROlHL-1852703 Subcellular response ol heart to
functional overload (hamsters, rats)
ROlHL-1871103 Electrophysiology ol heart cells (rats.
chicks)
ROIHL 19056-03 Blood triglycerides and lipoprotein lipase
in the lung (rats)
POIHL 19242 02 0001 Study of vascular smooth muscle
Energy metabolism and protein turnover in vascular smooth
muscle (rats)
ROlHL'20344-02 Regulation of protein turnover in lung
tissue (rats)
ROlHL-20366-03 Protein turnover and amino acid
transport by lung (rats)
ROlHL-2 1140-01 Studies of pulmonay alveolar
macrophage function (rabbits)
ROlHL-21418-02 Experimental myocardial infarction (rats)
ROlHL-22883-01 Lung epithelial cell interactions in vitro
ROlHL-23969-01 Surfactant synthesis by type II cells in
vitro (rats)
ENDOCRINOLOGY, HORMONES, PEPTIDE-
POLYPEPTIDE HORMONES
SEE ALSO BLOOD AND RE SYSTEM. HEMATOPOIETIC
FACTORS. ERYTHROPOIETIN
SEE ALSO GASTROINTESTINAL HORMONES, GASTRIN
SEE ALSO GASTROINTESTINAL HORMONES. PANCREOZYMIN-
CHOLECYSTOKININ
SEE ALSO GASTROINTESTINAL HORMONES. SECRCTIN
SEE ALSO GROWTH FACTORS (INCL. ANABOLICS), EPIDERMAL
GROWTH FACTOR
SEE ALSO PANCREAS HORMONES. GLUCAGON
SEE ALSO PANCREAS HORMONES, INSULIN
SEE ALSO PARATHYROID HORMONES
SEE ALSO PEPTIDES, VASOACTIVE PEPTIDES
SEE ALSO PITUITARY-DIENCEPHALON (HORMONES)
SEE ALSO PITUITARY-DIENCEPHALON HORMONES, OXYTOCIN
SEE ALSO PITUITARY-DIENCEPHALON HORMONES, PROLACTIN
SEE ALSO PITUITARY-DIENCEPHALON HORMONES,
SOMATOTROPIN
SEE ALSO PITUITARY-DIENCEPHALON HORMONES,
THYROTROPIN
SEE ALSO PITUITARY-DIENCEPHALON HORMONES.
VASOPRESSIN
SEE ALSO THYROID HORMONES, (THYRO)CALCITONIN
P50HL- 142 14-07 0021 Newborn lung center for hyaline
membrane disease - Development of surfactant system-
Surfactant production and release (rat, rabbit)
P60HL-16005-05 0013 Comprehensive sickle cell center -
Study of regulation of erythropoiesis in vitro (human, rat,
hamster, rabbit)
ROlHL-18070-04 Regulation of intrapulmonary airways
and vessels (human, animals)
ROlHL-18845-04 Regulation of renal circulation and salt
excretion (rats, dogs)
ROlHL-19195-03 Hormonal regulation of lung function
(rats)
ROlHL-21272-02 Sodium homeostasis and renal
prostaglandins (dogs)
" ROlHL-21676-02 Purification and properties of
erythropoietin (human)
** ROlHL-21683-02 Purification of erythropoietin (human)
** ROlHL-21692-02 Purification of erythropoietin (human)
** R01HL-21701-02 Purification of erythropoietin (human)
ROlHL-221 15-02 Lipid-mobilization and diabetic
atherosclerosis (human)
ROlHL-22411-01 Neuroendocrine involvement in
hypertension (rats)
ENDOCRINOLOGY, HORMONES, STEROID
HORMONES
SEE ALSO ADRENAL CORTEX HORMONES
SEE ALSO ANDROSTANE SERIES, ANDROGENS
SEE ALSO ESTRATRIENE SERIES. ESTROGENS
SEE ALSO PROGESTERONE
Sri AIM PROGE'iIINS
S(l Also KII'HUUIICIIVE HORMONES. SEX HORMONES
RUIHI II6:I0 0H Control ot |lyco|in tynthetit in heart
(l4lllll')
ROIHI I4(i63 07 Pulmonary oxygen toxicity in newborn
lung (humiin. mice)
PbOHl 17292 04 0009 Vermont lung Center Controlled
cliniial Iriah on a clinical core unit (human)
POIMl 17419 04 0006 Studies on mechanisms ol
hemo'.taMS Ifleil ol hormones, drugs and other agentt
on libiinogen synthesis (chick)
•• P50H1 18323 04 0038 SCOR hypertension center
Unknown adrenocortical mechanisms in hypertension
(human)
POIHL 18574 03 0004 Lipoprotein methodology and
biomedical applications Fine structure and metabolism ol
lipoproteins EM studies (guinea pigs)
ROIHL 19115 02 Hormonal control ol tracheobronchial
cyclic AMP (rats, guinea pigs)
*• ROIHL 20201 01 Hypertension and vascular steroid
receptors (rats)
ROIHL 20922 02 Control ol human letal hemoglobin
synthesis
POIHL 2094802 0002 Molecular basis ol cholesterol
metabolism LDL pathway in cell lines with inlormative
properties other than fibroblasts
ROIHL 21112 02 Aldosterone binding, clearance, and
secretion in man
•* ROIHL 22079 01 Heart receptor sites lor digitalis and
steroid hormones (animals)
ROIHL 22500 01 Conversion ol choline to
phosphatidylcholine m lung (rabbits, pigs)
ENDOCRINOLOGY, HORMONES ANALOGS
SEE ALSO PEPTIDES. VASOACTIVE PEPTIDES
•• POIHL 12738 10 0129 Physiologic pharmacology and its
clinical applications Receptor specilicities and
metabolism ol vasopressin analogs
P60HL 16008 06 0015 Wayne State University
comprehensive sickle cell center Trace elements in sickle
cell disease (human)
ROIHL- 180 15-03 Pharmacologic studies on vascular
smooth muscle (dogs, rats)
ROlHL-18272-03 Heart adenyl cyclase complex (beef
heart)
ENDOCRINOLOGY, HORMONES BIOSYNTHESIS
SEE ALSO PROTEINS BIOSYNTHESIS
SEE ALSO STEROIDOGENESIS
P01HL-06285-18 0193 Cardiovascular-respiratory
physiology and biochemistry - Hormonal regulation of
sodium transport -Aldosterone (rats, toads)
ROlHL-09921-13 Mechanisms related to congestive heart
failure (dogs, human, rat)
POlHL-14388-07 0179 Regulation of the circulation in
pathological states Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
ROlHL-15685-05 Hemopoietic regulators produced in cell
culture (human, animals)
** R01HL16524-02 Selective inhibitors of prostaglandin
biosynthesis (dogs)
ROlHL-18730-03 Role of mineralocorticoids in low renin
hypertension (human, rats)
ROlHL-19455-03 Role of endothelial cells in vascular
permeability (tissue culture)
ROlHL-21764-01 Ultramicroanalysis of prostaglandins and
related compounds (rats)
" R23HL-21917-01 Adrenal steroids in adolescent and adult
hypertension
ENDOCRINOLOGY, HORMONES BIOSYNTHESIS,
PEPTIDE-POLYPEPTIDE HORMONES
BIOSYNTHESIS
** P50HL-142 14-07 0024 Newborn lung center for hyaline
membrane disease - Synthesis and receptors for ACTH in
fetal lung (human)
P60HL-16005-05 0022 Comprehensive sickle cell center -
Regulation of erythropoiesis in patients with sickle cell
anemia
ROlHL-19653-03 Circulatory system effects of angiotensin
analogs (rats)
ROlHL-21686-02 Purification of erythropoietin (human)
ENDOCRINOLOGY, HORMONES BIOSYNTHESIS,
STEROID HORMONES BIOSYNTHESIS
POlHL-1141411 0014 Thrombosis and atherosclerosis
program - Role of adrenal in human essential hypertension
P50HL-18318-03 0004 Pathogenesis and complications of
hypertension - Steroid and renin profiles in hypertension
(rats, human)
P50HL-18318-03 0009 Pathogenesis and complications of
hypertension - The mineralocorticoid-hypertensive syndrome
in man
ENDOCRINOLOGY, HORMONES INHIBITORS
SEE ALSO ADRENAL CORTEX HORMONES. ALDOSTERONE
INHIBITORS
SEE ALSO ADRENAL CORTEX (HORMONES) INHIBITORS
SEE ALSO PITUITARY-DIENCEPHALON HORMONES, ACTH
INHIBITORS
SEE ALSO THYROID ANTAGONISTS
** POlHL-06835-17 0032 Cardiovascular disease - Synthesis
of angiotensin II as inhibitors for aldosterone
(contd)
^Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
**On€nted significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
END
ROlHL-1 1802-10 Cardiovascular surgical research (dogs,
sheep, swine, cats, monkeys)
ROlHL-1189711 Pathogenesis of experimental
atherosclerosis (rabbits, guinea pigs)
P50HL-14192-08 0007 Specialized center of research in
hypertension ■ Role of new mineralocorticoids in
hypertension (human, rats)
R01HL14509-07 Hypertension -Chemistry and biophysics
of angiotensin
P50HL-18323-04 0037 SCOR hypertension center -
Adrenocortical factors in childhood hypertension
R01HL19057-03 Catecholamines and cyclic AMP in
cardiovascular system (rats, dogs)
ROlHL-22069-02 Experimental renal arterial hypertension
(dogs)
R23HL-22346-01 Hematological injury and pulmonary
dysfunction (human, mammals)
ROlHL-22520-01 Pulmonary vascular response to group B
Streptococci (human, mammals)
ENDOCRINOLOGY, HORMONES METABOLISM
ROlHL-22051-01 Role of angiotensin 11 in vasopressin
release (human)
ENDOCRINOLOGY STUDY SECTION
** ROlHL-13715-08 Myocardial adenyl cyclase (rats)
** ROIHL 19195-03 Hormonal regulation of lung function
(rats)
** R01HL19644-03 Etiological factors in hypertension
(human, dogs, rats) .
** ROlHL-2287301 Adrenoceptor inlerconversion and
hormone homeostasis
ENDOCYTOSIS
SEE BIOLOGICAL TRANSPORT, ACTIVE TRANSPORT,
PINOCYTOSIS
ENDOLYMPH
SEE EAR, UBYRINTHINE FLUIDS, ENDOLYMPH
ENDOMYOCARDIAL FIBROSIS
SEE HEART DISORDERS, ENDOMYOCARDIAL FIBROSIS
ENDONUCLEASE
SEE NUCLEASES, ENDONUCLEASES (GENERAL)
ENDOPEROXIDES
SEE FATTY ACIDS, UNSATURATED FAHY ACIDS,
PROSTAGUNDINS
ENDOPLASMIC RETICULUM
SEE CELL COMPONENTS, ENDOPLASMIC RETICULUM
ENDOSCOPY
SEE DIAGNOSTIC TESTS, ENDOSCOPY*
ENDOTHELIOMA VASCULAR
SEE NEOPLASMS OF CARDIOVASCULAR SYSTEM,
HEMANGIOENDOTHELIOMA
ENDOTHEUUM VASCULAR
SEE CARDIOVASCULAR SYSTEM, ENDOTHELIUM
ENDOTHELIUM VASCULAR PERMEABILITY
SEE CARDIOVASCULAR SYSTEM, ENDOTHELIUM
PERMEABILITY
ENDOTOXIN SHOCK
SEE BLOOD TOXICOLOGY, BACTEREMIA-SEPTICEMIA
ENDOTOXINS
SEE IMMUNOLOGY, ANTIGENS BACTERIAL, ENDOTOXINS
ENDOXAN
SEE HALOALKYLAMINES, CYCLOPHOSPHAMIDE
ENERGETICS OF BIOLOGICAL TRANSPORT
SEE BIOLOGICAL TRANSPORT, TRANSPORT ENERGETICS
ENERGY DEPENDENT TRANSPORT
SEE BIOLOGICAL TRANSPORT, ACTIVE TRANSPORT
ENERGY SYSTEMS, BIOLOGICAL POWER
SOURCES
SEE BIOMEDICAL ENGINEERING, BIOLOGICAL POWER
SYSTEMS
ENGINEERING, BIOMEDICAL
SEE BIOMEDICAL ENGINEERING
ENOLATES
SEE CARBOXYLIC ACIDS, ENOLATES
ENOLS
SEE ALCOHOLS, ENOLS
ENOVIO
SEE FERTILITY. ANTIFERTILITY DRUGS, MESTRANOL-
NORETHYNODREL
ENTERIC BACTERIA
SEE BACTERIA, ENTERIC (GENERAL)*
ENTEROCHROMAFFINOMA
SEE NEOPUSMS OF NERVOUS SYSTEM, CARCINOID
ENTEROCOCCI (STREPTOCOCCUS)
SEE BACTERIA, STREPTOCOCCACEAE, STREPTOCOCCUS,
ENTEROCOCCUS GROUP*
M
198
ENTEROHEPATIC CIRCULATION
SEE BILE ACIDS AND SALTS, ENTEROHEPATIC CIRCULATION
ENVELOPE, VIRAL
SEE VIRUS COMPONENTS, CAPSID AND ENVELOPE
ENVIRONMENT
SEE ALSO CARDIOVASCULAR DISORDERS, HYPERTENSION
(SYSTEMIC), ENVIRONMENT-ASSOCIATED
SEE ALSO SOCIOENVIRONMENT
** P01HL144 14-07 0014 Environmental influences on
cardiorespiratory and cellular functions • Temperature and
acid-base status in tissues, cells, and subcellular system
ROlHL-18848-03 Etiology and development of congenital
heart disease (dogs, cats)
ENVIRONMENT, ADAPTATION
SEE ALSO PSYCHOLOGICAL ADAPTATION
SEE ALSO WATER ENVIRONMENT, DIVING REFLEX
P0IHL-0629e-18 Cardiovascular and pulmonary
adaptation to stress
P01HL06296-18 0003 Cardiovascular and pulmonary
adaptation to stress - Human exercise studies (human,
dogs)
POlHL-07896-15 0039 Environmental biomedical research
program - Development of resistance to lethal effects of
oxygen (rats)
POlHL-0889914 Tolerance to respiratory gases in health
and disease
POlHL-08899-14 0007 Tolerance to respiratory gases in
health and disease - Effects of high oxygen pressures on
visual function (human, animals)
POlHL-08899-14 0015 Tolerance to respiratory gases in
health and disease - Respiratory adaptations to increases
in breathing (human)
P01HL08899-14 0064 Tolerance to respiratory gases in
health and disease - Narcotic effects of inert gases on
functional systems (rats)
P01HL08899-14 0065 Tolerance to respiratory gases in
health and disease - Adaptation and effects of narcotic
gases exposure (human)
POIHL 1310809 0023 Clinical heart transplantation ■
Adaptive mechanisms of the dencrvated heart (human)
P01HL1498507 Adaptation to hypoxia
POlHL-14985-07 0002 Adaptation to hypoxia - Oxygen
transport in man at high altitude
POlHL-14985-07 0004 Adaptation to hypoxia - Control of
breathing in respiratory failure (human, dogs)
POlHL-14985-07 0005 Adaptation to hypoxia - Control
mechanisms in the pulmonary microcirculation (animals)
P01HL14985-07 0007 Adaptation to hypoxia - Control of
pulmonary circulation, histamine and the sympathetics
(animals)
POlHL-1498507 0008 Adaptation to hypoxia - Ventilatoiy
drive and exercise capacity (human, dogs)
POlHL-14985-07 0009 Adaptation to hypoxia - Influence
of chemosensitivity on control of breathing during sleep
(human, dogs)
POlHL-14985-07 0010 Adaptation to hypoxia • Pulmonary
mast cell (animals)
POlHL-14985-07 0011 Adaptation to hypoxia -
Prostaglandins in the control of the pulmonary circulation
(animals)
POlHL-14985-07 0012 Adaptation to hypoxia - Direct
effect of hypoxia on pulmonary vascular smooth muscle
(rats, dogs)
POIHL 1498507 0013 Adaptation to hypoxia -
mountain sickness (men)
P01HL14985-07 0014 Adaptation to hypoxia
altitude pulmonary edema (human, rats, dogs)
POlHL-14985-07 0015 Adaptation to hypoxia ■
at high altitude (human, animals)
POlHL-14985-07 0016
Administrative core
P0IHL14985-07 0017
laboratories
POlHL-14985-07 0018 Adaptation to hypoxia ■
Bioengineering core
R01HL15430-05 Cardiopulmonary adaptation of newborns
to altitude (human)
ROlHL-15460-06 Molecular adaptation -Hemoglobin
systems of fish (marine)
Adaptation to hypoxia
Adaptation to hypoxia
Chronic
High
Pregnancy
Core
Human ventilatory adaptation (also.
Aging-tissue injury and repair (rats)
Innervation of coronary arteries and heart
R01HL15469-06
dogs, rats)
R01HL1633006
ROlHL-16657-06
(rats)
R01HL1732204 Functional characteristics of smooth
muscle isolated from lung (animals)
ROIHL-17970-04 Vascular effects of inhibitory behavioral
adaptations (dogs)
R01HL18145-03 Oxygen transport mechanisms in hypoxia
(dogs, rats, rabbits)
ROlHL-18560-03 Cardiovascular adaptation to stress
(miniature swine)
ROlHL-190 10-03 Metabolism and cell biology of lung
surfactant system (rabbits, sheep)
ROlHL-19248-03 Breathing pattern variation and
mechanical influences
ROlHL-2065502 Autonomic predictors of hypertension in
children
R01HL-20678-02 Cardiovascular adaptation to stress in
disease states (dogs)
ENV
Altitude adaptation in chronic lung
Dynamics of interstitial space in whole
Cardiac adaptation to physical training
Regulation of cardiac adaptation to
** ROlHL-2111701
disease (human)
** ROlHL-21282-01
animals (rats)
** ROlHL-22154-01
(dog)
** ROlHL-22361-01
exercise (rats)
** ROlHL-22667-01 Mechanisms of baroreceptor adaptation
in hypertension (dogs)
** ROlHL-23025-01 Adaptive heart growth in neonates and
adults (rats)
ENVIRONMENT, ADAPTATION,
ACCLIMATIZATION
P01HL08899-14 0008 Tolerance to respiratory gases in
health and disease - Hypoxia in regards to respiratory and
brain circulatory control (goats)
ROIHL 10009-13 Regional lung function in man
** R01HL-1384M6 Respiration during altitude
acclimatization (goats, dogs, rats, rabbits)
** ROIHL 14102-07 Human physiology at 5360 meters-
Mountain environment
** POlHL-1498507 0003 Adaptation to hypoxia • Hypoxia
and oxygen transport (human, dogs)
ROIHL 15659-05 Dynamic isolation studies of control of
respiration (human)
ROlHL-17732-03 Peripheral venomotor control in thermal
stress (human)
** ROlHL-2063401 Blood volume and venous return in
thermal strain (human)
ROlHL-21282-01 Dynamics of interstitial space in whole
animals (rats)
ENVIRONMENT, ADAPTATION, ESTIVATION
** P01HL08805-15 0006 Regulation of ventilation and
pulmonary circulation • Adaptation of lungfish-Estivation
ENVIRONMENT, ADAPTATION, HIBERNATION
POlHL-07896-15 0058 Environmental biomedical research
program - Lung synthesis of disaturated
phosphatidylcholine (rats, dogs, bats)
POlHL-08682-15 Regulation of the cardiovascular system
P01HL0868215 0006 Regulation of the cardiovascular
system - Cardiovascular studies of mammalian hibernators
(sciuromorpha)
POlHL-08682-15 0011 Regulation of the cardiovascular
system - Histochemistry and ultrastructure of heart
innervation (dogs, ground squirrels)
POlHL-08682-15 0031 Regulation of the cardiovascular
system - Cardiac electrophysiology in hibernation (ground
squirrel, marmot)
M
R01HL14713-06
pigs)
ROlHL-17847-04
marmots
Hypothermia and the heart (bats, guinea
Cardiovascular and renal functions of
ENVIRONMENT, ALTITUDE
SEE ALSO ENVIRONMENT, STRESS, ALTITUDE
ROlHL-02888-22 Interrelationships of circulation and
respiration (opossum, cats)
** POlHL-07896-15 0033 Environmental biomedical research
program - Breathing mechanism in birds
ROlHL-10009-13 Regional lung function in man
ROlHL-13841-16 Respiration during altitude
acclimatization (goats, dogs, rats, rabbits)
ROlHL'17711-05 Mechanism of hypoxic regulation of lung
circulation (rats, cats, guinea pigs)
ROlHL-18082-03 Erythrocyte phosphates and vertebrate
gas transport (amphibians, reptiles)
R01HL18191-04 Models of hypoxic pulmonary
hypertension (cattle, minipigs)
** ROlHL-21 117-01 Altitude adaptation in chronic lung
disease (human)
ROlHL-21126-02
children
ROlHL-21159-02
Exercise-induced bronchospasm in
Pathophysiological effects of hypoxia
(rats)
ENVIRONMENT, ATMOSPHERE (WEATHER)
SEE ALSO AIR POLLUTION
SEE ALSO ENVIRONMENT, EXTRATERRESTRIAL,
SUPRATERRESTRIAL
ROlHL-22528-02 Early risk predictors tor chronic
pulmonary disease (human)
ENVIRONMENT, ATMOSPHERE, HUMIDITY
ROlHL-13824-06 Defense mechanisms in pathogenesis of
emphysema (human, dogs)
P01HL14414-07 0004 Environmental influences on
cardiorespiratory and cellular functions - Role of diffusion
in gas exchange (chicken egg)
ROlHL-21126-02 Exercise-induced bronchospasm in
children
ENVIRONMENT, ATMOSPHERIC PRESSURE
SEE ALSO ENVIRONMENTAL CHAMBER CONTROLLED.
HYPERBARIC FACILITY
SEE ALSO INJURIES, DYSBARISM
SEE ALSO RESPIRATORY ASSIST AND OXYGEN
ADMINISTRATION, HYPERBARIC OXYGENATION
SEE ALSO RESPIRATORY GAS LEVELS
POlHL-07896-15 0033 Environmental biomedical research
program - Breathing mechanism in birds
(contd)
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Onented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
■NV
POIHL 07896 IS 00S9 Environinanlil blomgdical lesearch
program Hyptioxyianation at elevalad atmojplitiic
pmiksuie on tnyocacdial blood How (dogs)
POIHI 07896 lb 0060 Enviioninenlal biointdical mseaich
progiam Eltect ot pie^suia on d<>v«lopm«nt ol inatine
ciustacaan larvae
POIHL 08899 M Tolaranc* lo respiratory gasts in haallh
and disaasa
POIHI 08899 14 0006 Tolerance to resprralory gases in
health and disease Etiects ol extreme pressures ol inert
gases in macaque monkey
POIHL 08899 14 001 7 Tolerance lo respiratory gases in
health and disease Pulmonary tolerance (human, dogs)
POIHL'08899 14 0018 Tolerance lo respiratorY gases in
health and disease Ettects ol respiratory gases at
extreme pressures (human)
POIHL 08899 14 0023 Tolerance to respiratory gases in
health and disease Hypoxia and hyperoxra in respiratory
response in regards to PC02 (human)
POIHL 08899 14 0030 Tolerance to resprralory gases in
health and disease Dynamic characteristics ol respiratory
control components (human, cats)
POIHL 08899 14 0031 Tolerance to respiratory gases in
health and disease Studies in exercise (human, dogs)
Tolerance to respiratory gases in
Acid base related influences ol
199
Tolerance to respiiatory gases in haalth
POIHL 08899 14 0033
health and disease
hypoxia (human)
POIHL 08899 14 0064
health and disease
Tolerance to respiratory gases rn
Narcotic etiects ol inert gases on
lunctional systems (rats)
POIHL'08899 14 0065 Tolerance to respiratory gases in
health and disease Adaptation and effects of narcotic
gases exposure (human)
POIHL 08899 14 0066 Tolerance to respiratory gases in
health and disease Neurophysiological effects ol inert
gases in man
PO1HL08899 14 0067
health and disease
function in man
POlHL-0889914 0072
health and disease
Tolerance to respiratory gases in
Inert gas inlluences upon visual
Micropinocytosis in isolated capillary
Modilication of susceptibility to oxygen
Tolerance to respiratory gases in
Inert gas exchange isobaric gas
counterdilfusion and decompression
P01HL08899-14 0075 Tolerance to respiratory gases in
health and disease - Gas dilfusion rates and bubble
formation across membranes (animals)
POlHL-08899-14 0076 Tolerance to respiratory gases in
health and disease - Bubble lormation during gas
counterditlusion (hamsters)
P01HL08899 14 0077 Tolerance to respiratory gases in
health and disease - Isobaric gas supersaturation patterns
P01HL-U889914 0079 Tolerance to respiratory gases in
health and disease • Physiological lactors in
counterditlusion bubble lormation (human, pigs)
POlHL-08899-14 0080 Tolerance to respiratory gases in
health and disease - Dynamic quantitation ol continuous
isobaric gas embolization
** POlHL-14414-07 0004 Environmental inlluences on
cardiorespiratory and cellular lunctions - Role of diffusion
in gas exchange (chicken egg)
R01HL14495-05 Solid and structural mechanics of lungs
(mammals)
ROlHL-16666-05
endothelium
ROlHL-2225901
poisoning (rats)
ROlHL-22406-01 Isobaric vascular bubbles and
decompression sickness (goats, models)
ROlHL-23209-01 Autonomic receptors of the pulmonary
vasculature (mammals)
ENVIRONMENT, ATMOSPHERIC PRESSURE,
COMPRESSION-DECOMPRESSION
SEE ALSO ENVIRONMENT, EXTRATERRESTRIAL,
SUPRATERRESTRIAL
SEE ALSO WATER ENVIRONMENT. DIVING AND SWIMMING
M POlHL-0789615 Environmental biomedical research
program
** P01HL-07896-15 0009 Environmental biomedical research
program - Decompression sickness and computation of safe
diving tables (human, animals)
" POlHL-07896-15 0014 Environmental biomedical research
program - Mechanisms ot respiration and circulation
(human, dogs)
" POIHL-07896 15 0019 Environmental biomedical research
program - Hyperoxic myopia (human)
** POlHL-0789615 0029 Environmental biomedical research
program - Oxygen-helium diving resulting in high pressure
nervous syndrome (human, animals)
** P01HL07896-I5 0030 Environmental biomedical research
program - Narcosis caused by inert gases at raised
pressures (human, animals)
** P01HL07896-15 0045 Environmental biomedical research
program - Extravascular lung water dynamics in pulmonary
oxygen toxicity (human, baboons)
** POlHL-07896-15 0050 Environmental biomedical research
program - Fundamental decompression concepts using the
rat animal model
** POlHL-07896-15 0057 Environmental biomedical research
program • Effects of dipyridamole and aspirin on
decompression thrombocytopenia (human)
** POlHL-07896-15 0062 Environmental biomedical research
program < Vectorcardiograms during diving (human, dogs)
Tolerance to resprralory gaiti In
Inert gas exchange in the eye
Tolerance lo respiiatory gitas In
Oxygen toleranc* Ihunian, (ill,
« POIHI 08899 14
and disease
• POllll 08899 14 0003
health and disease
(human, dogs)
POIHL 08899 14 0020
health and disease
guinea pigs)
'• POIHL 08899 14 0022 Tolerance to respiratory gases In
health and disease Ellecl ol inert gas and hydrostatic
pressures on physiological lunctions (monkey)
POIHL 08899 14 0028 Tolerance to respiratory gases rn
health and disease Inert gas exchange, oxygen inlluences
organs and tissues (human, rabbits, dogs)
POIHL 08899 14 0029 Tolerance to respiratory gases in
health and disease Isobaric gas counter dillusion
phenomena (human, pigs)
POIHL 08899 14 0052 Tolerance to respiratory gases in
health and disease Oxygen etiects on auditory and
vestibular lunction (human, guinea pigs)
** POIHL 08899 14 0056 Tolerance to respiratoiy gases in
health and disease Extension ol pulmonary oxygen
tolerance at increased pressures (animals)
** POIHL 08899 14 0072 Tolerance lo respiratory gases rn
health and disease Inert gas exchange isobaric gas
counterditlusion and decompression
** POIHL 08899 14 0073 Tolerance lo respiratory gases in
health and disease Biophysical mechanisms involved in
isobaric gas counterdilfusion syndrome
" P01HL08899 14 0074 Tolerance to respiratory gases in
health and disease Biomathematical analysis ol isobaric
gas exchange and bubble lormation
•* POlHL-08899 14 0075 Tolerance to respiratory gases in
health and disease Gas ditlusion rates and bubble
lormation across membranes (animals)
*• POlHL-08899 14 0076 Tolerance to respiratory gases in
health and disease Bubble lormation during gas
counterdilfusion (hamsters)
** POlHL-08899-14 0077 Tolerance to respiratory gases in
health and disease Isobaric gas supersaturation patterns
** P01HL08899-14 0078 Tolerance to respiratory gases in
health and disease Isobaric gas counterdilfusion -Sensory,
cutaneous and systemic function (animals)
POlHL-08899-14 0079 Tolerance to respiratory gases in
health and disease - Physiological lactors in
counterdiltusion bubble formation (human, pigs)
POlHL-08899-14 0080 Tolerance to respiratory gases in
health and disease • Dynamic quantitation of continuous
isobaric gas embolization
** POlHL-08899-14 0085 Tolerance to respiratory gases in
health and disease - Search lor gas bubbles in vestibular
lluids (animals)
" POlHL-08899-14 0089
health and disease
optimal control theory
POlHL-144 14-07 0003 Environmental inlluences on
cardiorespiratory and cellular lunctions - Exposure to
abnormal gaseous environments (human, dogs, rabbits)
** ROlHL-16254-05 Pathogenesis ol bubble and clot
lormation dish)
ROlHL-16855-03 Cavitation in biological systems
(microorganisms, animals)
ENVIRONMENT, CUAAATE
SEE ALSO ENVIRONMENT. ADAPTATION. ACCLIMATIZATION
P50HL-14136-07 0016 Pulmonary SCOR-Airways
obstructive diseases - Environmental factors in airways
obstructive diseases (human)
ROlHL-15614-04 Heredity and oxygen-Effects on health of
heart-lungs (South America)
P60HL-15996-06 0005 Cincinnati comprehensive sickle
cell center • Factors precipitating crises (human)
ENVIRONMENT, CLIMATE, COLD
SEE ALSO TEMPERATURE. COLD
** ROlHL-207 19-02 Cold induced pulmonary hypertension
(cattle)
ENVIRONMENT, CLIMATE, SEASONS
ROlHL-147 13-06 Hypothermia and the heart (bats, guinea
pigs)
ROlHL-17322-04 Functional characteristics of smooth
muscle isolated from lung (animals)
ROlHL-19487-03 Cardiac actions of digitalis (dogs, cats)
ENVIRONMENT, ECOLOGY ANIMAL
SEE ALSO TOXICOLOGY. ENVIRONMENTAL
ROlHL-01979-22 Arteriosclerosis in zoo animals on
controlled diets (animals)
R01HL-17958-04 Circulatory effects ol operant
cardiovascular control (baboons)
** ROlHL-18082-03 Erythrocyte phosphates and vertebrate
gas transport (amphibians, reptiles)
ENVIRONMENT, ECOLOGY HUMAN
SEE ALSO CARDIOVASCULAR DISORDERS. HYPERTENSION
(SYSTEMIC). ENVIRONMENT-ASSOCIATED
SEE ALSO ENVIRONMENTAL HEALTH (GENERAL)
SEE ALSO POPULATION STUDIES HUMAN
SEE ALSO SOCIAL GROUPS. ETHNIC
SEE ALSO SOCIOENVIRONMENT
SEE ALSO TOXICOLOGY, ENVIRONMENTAL
** R01HL15614-04 Heredity and oxygen -Effects on health of
heart-lungs (South America)
Tolerance to respiratory gases in
Decompression by applications of
fNV
ROIHI 20H/'ia2 (hronir obttructivt pulmonary diMaw
lamlllal/ganetic (human)
ROIHI 70910 0? The aheinilivii di«l tor coronary dlM*M
prevention (human) <
•• R01HL2II26 02 CarclM induc»d bioncho\pa»ni in
rhildren
ENVIRONMENT, ECOLOGY ORGANISMS, HOST-
ORGANISM
SIf Also VIRUS DISEASr CMAHACIIRIMItS HOST VIRUS
ROlHt 11880 10 Physiology and pathology ol blood
platelets (human, dogs)
POIHL 16833 04 0016 Hemoglobin and red cell system rn
hemoglobinopathies Calcium indiced membrane damage
in Hb SS disease (human, animals)
P50HL 14171 02 0006 Pulmonary SCOR Lung Injury by
childhood inlections Development ol model systems
(bacteria, viruses, hamsters)
•• P60HL 19171 02 0008 Pulmonary SCOR Lung injury by
childhood infections Host parasite interaction Electron
microscopy, radioautography, histochemistry
"* P50HI 19171 02 0009 Pulmonary SCOR lung injury by
childhood inlections Host parasite interaction Scanning
electron microscopy, Ireeze Iracture methods
*• P50HL 19171 02 0010 Pulmonary SCOR Lung injury by
childhood inlections Metabolic pathways ol normal and
injured respiratory cells
ROI.IL 20170 02 Pulmonary inlection in splenectomized
animals (mice)
R23HL 22823 01 Phagocytic and immune delense
mechanisms ol the lung (mice)
ENVIRONMENT, EXTRATERRESTRIAL,
SUPRATERRESTRIAL
SEE ALSO ENVIRONMENT, ATMOSPHERE (WEATHER)
SEE ALSO ENVIRONMENT, ATMOSPHERIC PRESSURE,
COMPRESSION DECOMPRESSION
SEE ALSO ENVIRONMENT, STRESS, ALTITUDE
POlHL-06296-18 0002 Cardiovascular and pulmonary
adaptation to stress Respiratory muscle blood flow,
mechanics and metabolism (human, dog)
ENVIRONMENT, GRAVITY -MOTION
POlHL-04664 18 0005 Cardiovascular and lung dynamics
Applications ol current research, equipment and
techniques
POIHL 11678-11 0058 Cardiovascular dynamics and their
control - Overall control of the circulation -Computer
analysis
ROlHL-14495-05 Solid and structural mechanics ol lungs
(mammals)
POlHL-15832-06 0005 Chemical-structural predispositions
to lung injury - Pulmonary structure and stress-strain
relationships (rats)
ROlHL-21518-01 Improvement in regional ventilation-
perlusion resolution (human)
POlHL-2 1584-02 0002 Respiratory mechanics in normal
and abnormal states - Lung mechanics-Regional
detormation and ventilation (dogs)
ROlHL-23985-01 Role of the diaphragm in regional lung
mechanics (dogs)
ENVIRONMENT, ORIENTATION
SEE ALSO SENSORY-PERCEPTUAL PROCESSES.
PROPRIOCEPTION
ROlHL-20861-01 Cardio-respiratory-renal stress reactions
(dog^)
ENVIRONMENT, ORIENTATION, CHEMOTAXIS
POlHL-03174-23 0001 Mechanisms ol acute vascular
reaction to injury Response ot the vascular intima to
injury (human, rats)
" POlHL-06314-17 0052 Immunologic mechanisms in
cardiovascular disease - Role of cyclic nucleotides in
neutrophil function (human)
P50HL 14230 07 0092 A/S SCOR-Lipids. atherosclerosis
and thrombosis Tissue liplds-Cell culture studies
(human)
ROlHL-17964 04 The alternate pathway for fibrinolysis
(human)
P01HL-1^827-02 0006 Platelet vessel wall interactions in
thrombogenesis - Platelet immune injury in man
R23HL21134-02 Immune function and fibrogenesis in
silicosis (isuinea pigs)
** ROlHL-21988-01 Biochemistry of human platelet
chemotaxis
ENVIRONMENT, STRESS
SEE ALSO FNVIRONMENT, ADAPTATION
SEE ALSO INJURIES (HAZARDS AND INSULTS)
SEE ALSO PREGNANCY. PRENATAL STRESS
SEE ALSO PSYCHOLOGIC STRESS
** ROlHL-02228-24 Respiration, circulation, and heat
regulation in exercise (bird, mammals)
P01HL-062S5-18 0125 Cardiovascular respiratory
physiology and biochemistry - Myocardial function rn the
fetal and neonatal lamb
P01HL06285-18 0157 Cardiovascular-respiratory
physiolcjy and biochemistry - Left ventricle outflow
impedance analysis (human)
M POlHL-06296-18 Cardiovascular and pulmonary
adapta'ion to stress
(contd)
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
**Onented significantly to atxive subject.
M Grant has subprojects descnbing specific researcli aspects.
See Appendix for investigator's name and grant number.
Pathogenesis of bubble and clot
Aging-tissue injury and repair (rats)
Effect of training-detraining on the rat
ENV
POlHL-08682-15 0023 Regulation of the cardiovascular
system - Cardiovascular control-Effects of spinal pathways
lesions (dog)
POlHL-08899-14 0041 Tolerance to respiratory gases in
health and disease - Blood gas transport and brain
circulatory control (human)
POlHL-08899-14 0064 Tolerance to respiratory gases in
health and disease - Narcotic effects of inert gases on
functional systems (rats)
ROlHL-09172-15 Protein and RNA synthesis in heart
muscle (rats)
ROlHL-12174-11 Ventilation/perfusion distribution in the
lung (human, mammals)
ROlHL-13193-09 Pathophysiology of post-traumatic and
shock states (rodents, dogs)
ROlHL-13408-05 Environmental-genetic interactions in
hypertension (rats)
P50HL- 14 159-08 0018 Specialized center of research in
hypertension - Sympathetic nervous system in hypertension
(rats)
M POlHL-14414-07 Environmental influences on
cardiorespiratory and cellular functions
ROlHL-14495-05 Solid and structural mechanics of lungs
(mammals)
ROlHL-15174-06 CV disease epidemiology -Second
generation studies (human)
ROlHL-16135-05 Mechanisms of cardiac autorhythmicity
(dogs, bats)
ROlHL-1625405
formation (fish)
ROlHL-16330-06
ROlHL-16420-02
heart
ROIHL 16916-04 0011 The role of albumins in lung water
accumulation - Whole body distribution and exchange of
albumin (rabbits, human, monkeys)
ROlHL-16952-05 Cardiovascular pathology (rats, rabbits)
** ROlHL-1 7580-04 The impact of stress on coronary heart
disease (men)
ROlHL-1 7706-04 Psychosocial hypertension,
catecholamines and drugs (mice)
POlHL-17731-04 0002 Physiological basis of pulmonary
disease - Biomechanics of the lung (frogs, cats)
R25HL-18418-03 Role of a supporting partner in
adherence (human)
R01HL1864403 Prosthesis for aortocoronary bypass
(dogs, baboons)
" ROlHL-18907-03 Objective evaluation early after Ml and
heart surgery (human)
ROlHL-19182-03 Surgical aspects of myocardial
hypertrophy (dogs)
ROlHL-19394-03 Biochemistry and regulation of taurine in
the heart (rats, guinea pigs, cats)
ROlHL-19410-03 Dynamic interrelations underlying
exercise hyperpnea (human)
ROlHL-19567-03 Impact of emotion on coronary arteries
(human)
ROlHL-19974-02 Psychologic-behavioral influences on
heart pathology (rats)
ROlHL-20364-01 Episodic hypertension associated with
human behavior (air traffic controllers)
ROlHL-20384-09 Social stimulation, RNA and
cardiovascular disease (animals)
ROlHL-20655-02 Autonomic predictors of hypertension in
children
ROlHL-20678-02 Cardiovascular adaptation to stress in
disease states (dogs)
ROlHL-20920-01 Control of hemoglobin synthesis (baboon)
ROlHL-21126-02 Exercise-induced bronchospasm in
children
* ROlHL-21282-01
animals (rats)
* R23HL-21393-01
(rats)
ROlHL-22650-01
Dynamics of interstitial space in whole
Cardiac adaptation to aging and stress
Regulatory mechanisms of erythropoietin
production (human, rats, mice)
ROlHL-22651-01 Control of protein metabolism in heart
muscle
ROlHL-22809-01 Coronary-prone behavior and
cardiovascular reactivity (human)
R23HL-22972-01 Microcirculatory function in hypotension
(rats, hamsters)
ROlHL-23161-01 0003 Biology of myocardial ischemia -
Phosphorylase coupling to myocardial sarcoplasmic
reticulum (dog)
ENVIRONMENT, STRESS, ALTITUDE
ROlHL-02228-24 Respiration, circulation, and heat
regulation in exercise (bird, mammals)
POlHL-06285 18 0146 Cardiovascular-respiratory
physiology and biochemistry - Pathogenesis and detection
of hypoxic pulmonary edema (human, animals)
POlHL-08899-14 0030 Tolerance to respiratory gases in
health and disease - Dynamic characteristics of respiratory
control components (human, cats)
** ROlHL-14102-07 Human physiology at 5360 meters -
Mountain environment
P50HL-14187-07 0015 Pulmonary SCOR -Chemical
mediators in pulmonary vascular responses
Pathophysiologic responses of pulmonary capillary bed
(dog, human)
M POlHL-14985-07 Adaptation to hypoxia
-High
■ Pregnancy
Adaptation to hypoxia -
Adaptation to hypoxia Core
Adaptation to hypoxia -
200
** POlHL-14985-07 0002 Adaptation to hypoxia - Oxygen
transport in man at high altitude
" POlHL-14985-07 0003 Adaptation to hypoxia - Hypoxia
and oxygen transport (human, dogs)
** POlHL-14985-07 0004 Adaptation to hypoxia - Control of
breathing in respiratory failure (human, dogs)
** POlHL-14985-07 0005 Adaptation to hypoxia - Control
mechanisms in the pulmonary microcirculation (animals)
** POlHL-14985-07 0008 Adaptation to hypoxia - Ventilatory
drive and exercise capacity (human, dogs)
** POlHL-14985-07 0009 Adaptation to hypoxia - Influence
of chemosensitivity on control of breathing during sleep
(human, dogs)
** POlHL-14985-07 0010 Adaptation to hypoxia - Pulmonary
mast cell (animals)
** POlHL-14985-07 0012 Adaptation to hypoxia - Direct
effect of hypoxia on pulmonary vascular smooth muscle
(rats, dogs)
** POlHL-14985-07 0013 Adaptation to hypoxia - Chronic
mountain sickness (men)
** POlHL-14985-07 0014 Adaptation to hypoxia
altitude pulmonary edema (human, rats, dogs)
" POlHL-14985-07 0015 Adaptation to hypoxia
at high altitude (human, animals)
** POlHL-14985-07 0016
Administrative core
** POlHL-14985-07 0017
laboratories
** POlHL-1498507 0018
Bioengineering core
ROlHL-15430-05 Cardiopulmonary adaptation of newborns
to altitude (human)
ROlHL-15469-06 Human ventilatory adaptation (also.
dogs, rats)
ROlHL-156 14-04 Heredity and oxygen-Effects on health of
heart-lungs (South America)
ROlHL-18145-03 Oxygen transport mechanisms in hypoxia
(dogs, rats, rabbits)
R23HL 22621-01 Blood cell-mediated pulmonary (human)
ROlHL-23224-01 Hypoxia and pulmonary vascular smooth
muscle (rat, cat)
ENVIRONMENT, STRESS, COLD INDUCED
P50HL-142 18-07 0017 Pulmonary SCOR -Newborn lung
center - Transvascular fluid exchange, vasoactive mediators
in RDS (sheep, cat)
ROlHL-21323-02 Raynaud's disease and temperature self-
regulation (human)
ENVIRONMENT, STRESS, HEAT INDUCED
SEE ALSO INJURIES. TEMPERATURE DEPENDENT. HEAT
INDUCED
ROlHL-02228-24 Respiration, circulation, and heat
regulation in exercise (bird, mammals)
POlHL-07896-15 0036 Environmental biomedical research
program - Respiratory heat loss in deep diving (infants,
dogs)
** ROlHL-17732-03 Peripheral venomotor control in thermal
stress (human)
** ROlHL-20634-01 Blood volume and venous return in
thermal strain (human)
ROlHL-20663-02 Regulation of skin blood flow in man
Control of circulation in heat stress
ROlHL-20766-02
(baboons)
ROlHL-21282-01
animals (rats)
ROlHL-21451-01
Dynamics of interstitial space in whole
Control of circulation during heat stress
and fever (baboon)
ENVIRONMENT, STRESS MECHANICAL
SEE ALSO MUSCLE FUNCTION, MUSCLE STRESS
SEE ALSO PHYSICAL PROPERTIES, TENSILE STRENGTH
POlHL-08682-15 0005 Regulation of the cardiovascular
system - Smooth muscle and mechanical properties of
blood vessels (dogs, human)
ROlHL-09562-14 Cardiac protein synthesis, overload,
alcohol and anoxia (guinea pigs)
** ROlHL-11289-12 Analysis of stress in pulsatile dynamics
ROlHL-12083-11 Flow field in aorta and its major
branches (dogs, phantom models)
ROlHL-12494-10 Continuum mechanics in biophysics
(human, animals)
ROlHL-12839-09 Flow, transport and membrane
phenomena in blood (human)
** R01HL-13437-09 Physical and mechanical parameters in
the microcirculation (animals)
ROlHL-13803-07 Advanced cardiac valvular and vascular
prosthesis (dogs, baboons)
** P01HL1438807 0214 Regulation of the circulation in
pathological states - Deformation pattern and stress
analysis of the left ventricle
" POlHL-14388-07 0215 Regulation of the circulation in
pathological states - Left ventricle model in
pathophysiologic states
POlHL-14388-07 0216 Regulation of the circulation in
pathological states - Development and regression of
ventricular hypertrophy (cats, rats)
POlHL-14388-07 0219 Regulation of the circulation in
pathological states - Myocardial ischemia and infarction in
animals (dogs)
POlHL-14388-07 0221
pathological states -
(dogs)
Regulation of the circulation in
Experimental myocardial infarction
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level
Onerrted significantly to above subject.
M Grant has subprojects descnbing specific research aspects
See Appendix for investigator's name and grant number.
ENV
** POlHL-14580-07 0001 Program project in respiratory
mechanics - Micromechanics of the lung (dogs, rats)
** P50HL-15062-07 0020 Study of lipoproteins, artery wall,
and atherosclerosis - Artery wall reactions -Elevated
pressure and hyperlipemia (monkey)
P60HL-15162-07 0019 Comprehensive sickle cell center -
RBC-Blood rheology in sickle cell anemia and related
disorders (human, animal)
** POlHL-15195-04 0003 Program project in biological
materials - Mechanical evaluation and fabrication
** ROIHL- 152 70-06 Local mechanical properties of the aortic
tissue (dogs, pigs)
** POIHL- 15832-06 0005 Chemical-structural predispositions
to lung injury - Pulmonary structure and stress-strain
relationships (rats)
ROlHL-16768-04 The sympathetic nervous system and the
arterial wall (rabbits, pigeons)
** ROlHL-16938-05 Effect of physical forces on blood (dogs,
human)
P60HL- 17269-04 0032 National heart and blood vessel
research and demonstration center - Clinical circulatory
assist device fabrication
** ROlHL-17437-03 'Perfusion lung'-Role of traumatized
leukocytes (dogs, human)
POlHL-17731-04 0001 Physiological basis of pulmonary
disease - Mechanisms of blood flow and ventilation (dogs)
ROlHL-17821-03 Cavitation phenomena near prosthetic
devices
ROlHL-18156-02 Hemodynamics in curved arteries
P01HL-18208-04 0006 Center for the study of blood cell
rheology - Analysis of flow in arterioles and capillaries
(human)
ROlHL-18321-03 Fluid shear or magnetic alignment of
blood components (human)
ROlHL-18527-03 Subcellular response of heart to
functional overload (hamsters, rats)
POlHL-18576-03 0001 Thrombosis research program
project - Platelet damage from physical forces and
artificial surfaces (human)
ROlHL-18584-03 Effects of physical forces on platelets
(human)
ROlHL-19677-03 Venous structure and function (dogs)
** ROlHL-19830-02 Shear to aortic histamine synthesis and
permeability (dogs)
ROlHL-19995-02 Sensory transduction in cardiac
mechanoreceptors (cats, frogs, rats)
POlHL-21584-02 0001 Respiratory mechanics in normal
and abnormal states - Engineering analysis of lung
deformation (human, animals)
ROlHL-22223-01 The cardiopulmonary junction (dogs,
models)
ROlHL-23206-01 Repetitive exercise and cardiac
enlargement (dogs)
NOlHV-72918-01 Test polymers for circulatory assist
devices
NO lHV-729 19-01 Test polymers for circulatory assist
divices
ENVIRONMENT-ASSOCIATED HYPERTENSION
SEE CARDIOVASCULAR DISORDERS. HYPERTENSION
(SYSTEMIC). ENVIRONMENT-ASSOCIATED
ENVIRONMENT CONTROLLED
SEE ALSO ENVIRONMENTAL CHAMBER CONTROLLED
POlHL-08899-14 0015 Tolerance to respiratory gases in
health and disease - Respiratory adaptations to increases
in breathing (human)
ENVIRONMENTAL CHAMBER CONTROLLED
POlHL-08682-15 0006 Regulation of the cardiovascular
system - Cardiovascular studies of mammalian hibernators
(sciuromorpha)
** ROlHL-15810-06 Electrolyte physiology and respiratory
acid-base (dogs)
ROlHL-18308-03
transport (dogs)
P50HL-19170-02 0004 Harvard pulmonary SCOR-Chronic
diseases of the airways - Exercise, increased ventilation
effect on airway exposure and responses (rodent)
ENVIRONMENTAL CHAMBER CONTROLLED,
HYPERBARIC FACILITY
SEE ALSO INJURIES, DYSBARISM
SEE ALSO RESPIRATORY ASSIST AND OXYGEN
ADMINISTRATION, HYPERBARIC OXYGENATION
POIHL-07896-15 0030 Environmental biomedical research
program - Narcosis caused by inert gases at raised
pressures (human, animals)
POlHL-07896-15 0036 Environmental biomedical research
program - Respiratory heat loss in deep diving (infants,
dogs)
POlHL-07896-15 0051 Environmental biomedical research
program - Relationships of retinal circulation to disease
(rabbits)
POlHL-14414-07 0004 Environmental influences on
cardiorespiratory and cellular functions - Role of diffusion
in gas exchange (chicken egg)
POlHL-14414-07 0010 Environmental influences on
cardiorespiratory and cellular functions - Pressure effects
on cardiac electrical phenomena (animals)
POlHL-14414-07 0016 Environmental influences on
cardiorespiratory and cellular functions - Effects of
(contd)
Comprehensive studies of mucociliary
INV
prtsiui* on mcmbxnt and cdlulti lunclioii (human.
rabbits)
•• POIHI 14414 0/ 9003 tnvitonmanlal inlliiences on
caidioospnalory and cellulai tunrlions Maihinr ond
alootiunics shop Com lacilily
ENVIRONMENTAL CONTAMINANTS (GENERAL)
Sf[ tNVIRONMlNIAl IKAIIH CONIAMINAIION (GfNfRAl)
ENVIRONMENTAL HEALTH (GENERAL)
SEE ALSO CONSUMER PRODUCTS
SEE ALSO ENVIRONMENI. ECOLOGY HUMAN
SEE ALSO EPIDEMIOLOGY AND DISEASE CONTROL STUDY
SECTION
SEE ALSO OCCUPATIONAL HEALTH
SEE ALSO PHYSICAL PROPERTIES. SOUND. NOISE POLLUTION
SEE ALSO RESPIRATORY DISORDERS. ENVIRNOMENTAL
POLLUTANTS ASSOCIATED
P60HL 17292 04 0003 Vermont Lung Center Subclinical
pulmonary disease in a rural environment (human)
ENVIRONMENTAL HEALTH, CONTAMINATION
(GENERAL)
SEE ALSO AIR POLLUTION
SEE ALSO CONGENITAL ABNORMALITIES. TERATOGENIC
AGENTS
SEE ALSO GENETICS. MUTAGENS
SEE ALSO NEOPLASTIC TRANSFORMATION. CARCINOGENS
(GENERAL)
SEE ALSO PESTICIDES BIOLOGICAL EFFECTS (GENERAL)
SEE ALSO PHYSICAL AND/OR CHEMICAL AGENTS
INTERACTION (BIOLOGICAL AND ECOLOGICAL).
POLLUTANTS INTERACTION
SEE ALSO TOXICOLOGY
SEE ALSO TOXICOLOGY. ENVIRONMENTAL
P0\HL 03174 23 0011 Mechanisms ot acute vascular
reaction to injury ■ Mutagen metabolism by artery wall in
etiology of atherosclerosis (human, animals)
M P01HL0637017 Cardiopulmonaty and renal pathology
research center
P01HL06370-17 0015 Cardiopulmonary and renal
pathology research center • Pathogenesis ot chemically
induced tissue injury (rats)
ROIHL 1265008 Environmental pathobiology ot the lung
(hamsters, rats)
P50HL15061 07 0002 Response of lung to injury •
Oxidative metabolism, phospholipid synthesis, and response
to toxins (rats)
** P01HL16137-05 0008 Alveolar biology ■ Macromolecular
events in pulmonary cells in toxic environments (animals)
R23HL-21327-02 Molecular mechanisms of chemical
myocardiopathies (rats)
R23HL-21369-02 Tracheal mucin synthesis in experimental
bronchitis (rats)
ROIHL 22603-01 Trace metals, vascular activity and
hypertension (rats)
ENVIRONMENTAL POUUTANTS (GENERAL)
SEE ENVIRONMENTAL HEALTH. CONTAMINATION (GENERAL)
ENVIRONMENTAL POLLUTANTS ASSOCIATED
RESPIRATORY DISORDERS
SEE RESPIRATORY DISORDERS. ENVIRNOMENTAL
POLLUTANTS ASSOCIATED
ENVIRONMENTAL TOXICOLOGY
SEE TOXICOLOGY. ENVIRONMENTAL
ENrYME COMPLEXES
ROIHL-02477-23 Biosynthesis and function of lipids
(microorganisms, rats)
ROlHL-13035-08 Heart mitochondrial malate
dehydrogenase regulation
ROlHL-13619-09 Microsomal electron transport in liver
and heart (human, mammals)
P50HL-14147-08 0006 Specialized center of research in
thrombosis - Clearance mechanisms of coagulation
moieties (human, rabbits, rodents)
ROlHL-1470005 Humoral and lung protease-antiprotease
role in obstructive disease (human)
ROlHL-14992-07 Mechanism of thrombin action (human)
ROlHL-16549-04 Cardiotonic steroid-NaK ATPase
interactions (cattle)
** ROlHL-16628-05 Regulation of lipid metabolism (rats)
R01HL-I755903 Structural elucidation of heart
cytochrome-C oxidase
ROlHL-18089-04 Fatty acid metabolism in heart and its
regulation (swine, rats)
ROlHL-18304-03 FT-infrared spectroscopy of heart muscle
energetics (cattle)
ROlHL-1912904 Cardiac glycosides-Mechanisms of
cellular actions
ROlHL-2079402 Prostaglandin synthesis in human
platelets (also in sheep, rabbit)
ROlHL-21120-02 Membrane dynamics in alveolar
macrophages (rabbits)
ROlHL-22050-01 Organization of succinic oxidase in heart
ROlHL-22174-01 Assembly of membranes in heart and
yeast mitochondria
** ROlHL-22538-01 Myosin as a multi-enzyme complex (dogs.
rabbits)
ROlHL-22996-01 Venom proteases-Action on plasma
protease inhibitors (human)
201
ROIHl ^Jltil 01 0003 lliuluiy ol myocardial ltch«nil«
Phosphorylase couplini to myocardial sarcoplaimic
reticulum (do|>
ENZYME DEFICIENCY DISORDERS
SI I MIIAHOIIC DISOROIRS INHORN
ENZYME DEREPRESSION
SFT IN/YMl INDUCTION RIPRESSION DEREPRESSION
ENZYME ELECTRODES
SLF ELECTRODES. ENZYME"
ENZYME FEEDBACK
" POlHl 06285 18 020/ Cardiovascular-rispiratonf
physiology and biochemistry Feedback control ol
cholesterol synthesis in non hepatic tissues (animals)
P50HL 14147 08 0013 Specialized center ol research in
thrombosis Mathematical models ol blood coagulation
kinetics
ROIHL 18219 04 Regulation ol cholesterol metabolism
(rats)
ENZYME IMMOBILIZATION
SEE ALSO ELECTRODES. ENZYME*
ROIHL 20104 03 Pulmonary granulomatous inflaniinations
(mice)
ENZYME INDUCTION
SEE ENZYME INDUCTION REPRESSION DEREPRESSION
ENZYME INDUCTION-REPRESSION-
DEREPRESSION
ROlHL-03734-18 Metabolism of arterial tissue in
atherosclerosis (rabbits)
POlHL-06285 18 0178 Cardiovascular-respiratory
physiology and biochemistry - Biochemical regulation of
hypertrophy (rats, rabbits)
ROIHL 11901 12 0012 Ettects of metabolic surgery on
the hyperlipidemias Ileal bypass -Animal atherosclerosis
implications (pigeons, dogs, rabbits)
** ROIHL 12138-08 Nutritional regulation of enzyme activity
(rats, human)
POlHL-12373-10 0006 Cardiopulmonary physiology and
pathophysiology - Fatty acid metabolism-Regulation,
implications (human, mammals, birds)
*• ROlHL-12745-10 Enzymes and inhibitors of cholesterol
biosynthesis (rats, human, swine)
" ROIHL 1303508 Heart mitochondrial malate
dehydrogenase regulation
** ROIHL 13630-08 Control of glycogen synthesis in heart
(cattle)
P50HL-14230-07 0099 A/S SCOR-Lipids. atherosclerosis
and thrombosis - Morphological, cytochemical study ot
normal and altered vasculature (mice)
POlHL-14388-07 0172 Regulation of the circulation in
pathological states - cAMP-dependent protein kinase from
heart and vascular smooth muscle (guinea pigs)
** POlHL-14388-07 0194 Regulation of the circulation in
pathological states - Oopaminebeta-hydroxylase localization
and release in hypertension
ROlHL-14397-07 Hypertension -Angiotensin and
prostaglandin pharmacology (animals)
ROlHL-15002-07 Biochemical pharmacology of guanylate
cyclase in lung (cattle, rats)
** ROlHL-15979-05 Elastase, serum inhibitors and the
vasculature (human, swine)
P60HL-17269-04 0003 National heart and blood vessel
research and demonstration center - Atherosclerosis -Fatty
acid metabolism in cardiovascular tissue (human, chicken)
•* R01HL1788204 Regulation of HMG-COA reductase and
sterol synthesis (human, mammals)
POlHL-18974-03 0009 Experimental neurogenic
hypertension program - Biochemistry of brain tyrosine
hydroxylase (rats)
POlHL-18974-03 0010
hypertension program
PNMT in brain (rats)
R01HL19181-02 Regulation of heart cAMP-dependent
protein kinase (rodents)
** ROlHL-19237-03 Obstructive lung disease and alveolar
macrophages (human, animals)
ROIHL 19654-03 Biochemical-pharmacological evaluation
of lung cells (rabbits)
ROlHL-20787-02 Thromboxanes and prostaglandins-
Biochemical pharmacology (rabbits, human)
ROlHL-20807-02
(human)
ROIHl 7?5}8 01
labbiM
Myoiin a'.
nullianryma i.omplai ldo|>
Experimental neurogenic
Biochemistry and regulation of
Detection of familial hypercholesterolemia
Antitrypsin and other causes of chronic
ROlHL-21 156-02
lung disease
ROlHL-21246-02 Roles of cholesterol and its metabolic
regulation (CHO cell mutants)
R23HL-21421-01 Myocardial and vascular contractility and
cyclic nucleotides (cattle, rats)
ROlHL-22242-01 The converting enzyme of lung (cattle,
human)
ROlHL-22265-02 Isozymes of heart glutamate aspartate
transaminase (swine, ducks)
ROlHL-22266-01 Production of proteases by lung cells in
culture (human, rodents, rabbits, sheep)
R23HL-22383-01 Biosynthesis-Response to oxygen
depletion (human, primates, rats)
ENZYME INHIBITORS
S(( AIV) BIOOU COA(.UIAMON. ANIIIHMOMBIN
Sir Also PfPIIDC. VASOACIIVI HIPIIDI', ANtlKININ
POIHI 08805 15 004/ Regulation ol ventilalion and
pulmonary circolallon Extracranial metabolic, control of
ventilation (dogt, goatj)
ROIHl 09921 13 Macl.anumi related to congaitive heart
failure (dogs, human, rat)
ROIHl 10612 13 0019 Humoral laclort in heart failure
and hypertension Pathogenesis of hypertension in the
spontaneous hypertensive rat
POIHI 123/3 10 0012 Cardiopulmonary physiology and
pathophysiology Biochemistry of the sympathetic nervous
system (rats, rabbits, pigrons)
ROIHL 12585 10 Structural properties of malate
dehydrogenase (swine)
ROIHL 1303508 Heart mitochondrial malate
dehydrogenase regulation
ROIHl 1316008 Human thrombin (also cattle)
♦* ROIHL 13587 06 Synthesis of renin inhibitors and analog
phosphatides (rats)
ROIHL 1371508 Myocardial adenyl cyclase (rats)
P50HL 1419208 0004 Specialized center of research in
hypertension Isolation and characterization of pure renin
(swine, rats, human, rabbits)
P50HL 1421407 0026 Newborn lung center for hyaline
membrane disease Hemodynamic studies of HMD
Prostaglandins production and blockers (lambs)
P01H114388-07 0183 Regulation ol the circulation in
pathological states Vasopressin in cardiovascular
regulation (dogs, rats)
ROlHL-14397-07 Hypertension -Angiotensin and
prostaglandin pharmacology (animals)
ROlHL-14509-07 Hypertension-Chemistry and biophysics
of angiotensin
P50HL-15061-07 0002 Response of lung to injury
Oxidative metabolism, phospholipid synthesis, and response
to toxins (rats)
ROIHL 1547605 Mechanism and control of sterol
biosynthesis (rats)
POlHL-15832-06 0004 Chemical structural predispositions
to lung injury Proteolytic activity leucocytes in patients
with obstructive lung disease
ROIHL 1624005 The cardiac histamine receptor (rabbits,
guinea pigs)
ROlHL-16320-05 Vasoactive peptides which stimulate
smooth muscles (rats, human)
ROlHL-16796-05 Cholesterol regulation by HMG-CoA
reductase (rats, human)
ROlHL-16872-04 Antihemophilic factor (human)
ROlHL-17332-04 Use of the gut for therapy of coronary
artery disease (mammals)
** ROlHL-17736-04 Metabolic change during cardiac
ischemia (rats, dogs)
POlHL-17871-04 0010 Kidney, sodium, cardiac output,
arterioles and hypertension - Renal prostaglandins
metabolism in hypertension (rats, dogs)
P50HL-18318-03 0019 Pathogenesis and complications of
hypertension - Renin-angiotensin system in blood pressure
regulation (human, rat, dog)
P50HL- 18323-04 0012 SCOR hypertension center - Renin
as a risk factor (human)
P50HL-18323-04 0033 SCOR hypertension center - Core
laboratory-Renin, aldosterone and bradykinin methodology
P50HL-18323-04 0042 SCOR hypertension center • Blood
viscosity and blood volume in hypertensive disease
(human, dog)
P50HL- 18323-04 0044 SCOR hypertension center -
Angiotensin blockade to identify angiotensin II factor in
hypertension (human)
P50HL- 18323-04 0046 SCOR hypertension center -
Coronary artery bypass surgery-Associated hypertension
(human)
R01HL18579-03 Vasoactive hormones and blood pressure
regulation (dogs, rats, rabbits)
•* ROlHL-18598-03
digitalis action
Role of Na, KATPase inhibition on
Prostaglandin precursors and vascular
ROlHL-22486-01
cells (swine)
Enzyme regulation in cultured arterial
R01HL187 18-04
reactivity (dogs)
ROlHL-1893203 Brain microcirculation observed in vivo
after trauma (mice)
ROlHL-19148-03 Myocardial organelle lipid structure and
function (dog, rat)
P50HL-19153-02 0001 SCOR-Pulmonary edemas-Eitology,
pathogenesis - Prostaglandins and the lung circulation
(sheep)
R01HL19237-03 Obstructive lung disease and alveolar
macrophages (human, animals)
ROlHL-19374-03 Pharmacology of kinins in cardiovascular
disease (rats, rabbits)
ROlHL-19517-03 Synthesis of inhibitors for the study of
renal renin (dogs, monkeys)
ROlHL-19538-03 Synthesis of potential antihypertensive
agents
R01HL19653-03 Circulatory system effects of angiotensin
analogs (rats)
POlHL-19717-02 0002 Response of the lung to injury •
Prolyl hydroxylase, lysyl hydroxylase and lung collagen
biosynthesis (rabbits)
(contd)
•Excludes routine metiiodology OR covers only seneral projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
The etiology of genetic hypertension
ENZ
ROlHL-20176-02 Biochemistry and genetics of salt
hypertension (rats)
ROlHL-20544-02 Integrated regulation of myocardial
energy metabolism (rats, guinea pigs)
ROlHL-20577-03 The mechanism of action of vitamin K
R01HL-20658-0I Myocardial energy transport-Creative
kinase (human, cattle, dog)
ROlHL-20787-02 Thromboxanes and prostaglandins-
Biochemical pharmacology (rabbits, human)
POlHL-2094802 0002 Molecular basis of cholesterol
metabolism • LDL pathway in cell lines with informative
properties other than fibroblasts
POlHL-2098402 0001 Cellular mechanisms in cardiac
hypertrophy - Contractile proteins in cardiac hypertrophy
(rabbits, calves)
ROlHL-21274-01 Frorenin -Physiological and biochemical
analysis (human)
R23HL-21421-01 Myocardial and vascular contractility and
cyclic nucleotides (cattle, rats)
ROlHL-2 1457-01 C(l?)-side group geometry and
cardenolide activity (cats, guinea pigs)
ROlHL-21540 02 Specific inhibitors of coagulation and
fibrinolysis (rats, rabbits, dogs)
ROlHL-2222501 Hormonal regulation of blood pressure
and blood flow (human, animals)
ROlHL-22288-01 Renin and precursors-Structure and
function (mice)
R23HL-22309-01 Cardiovascular pharmacodynamics in
immature dogs
R23HL-2243801
(rats)
POlHL-22619-01 0004 Cellular mechanisms of heart
failure ■ Mechanism of action of Na. K ATPase (sheep.
cattle)
** ROlHL-22813-01 Palmitylcarnitinc inhibition of ion pumps
in ischemia (dogs)
ROlHL-22990-01 Angiotensin II receptors-Mechanisms of
regulation (rats)
** ROlHL-22996-01 Venom proteases -Action on plasma
protease inhibitors (human)
ROlHL-23161-01 0002 Biology of myocardial ischemia -
Palmitylcsrnitine inhibition of ion pumps in myocardial
ischemia (dog. sheep)
** NOlHR-72921 01 Cystic fibrosis factor Identification and
quantification (human)
ENZYME INHIBITORS, ANTIESTERASES
ROlHL-1569007 Hydrolytic enzymes of blood in health
and disease (human, animals)
ENZYME INHIBITORS, CARBONIC ANHYDRASE
INHIBITORS
POlHL-0789615 0019 Environmental biomedical research
program • Hyperoxic myopia (human)
P01HL14985-07 0009 Adaptation to hypoxia ■ Influence
of chemosensitivity on control of breathing during sleep
(human, dogs)
POlHL-17731-04 0010 Physiological basis of pulmonary
disease ■ Gas exchange kinetics (dogs)
ROlHL-17963-04 Human erythrocyte carbonic anhydrase
ROlHL-19008-02 Carbon dioxide diffusion in lung and
muscle tissues (dogs)
ROlHL-2225801 New aspects of pharmacology related to
carbonic anhydrase
ENZYME INHIBITORS, DECARBOXYLASES
INHIBITORS
ROlHL-17754-03 Pathogenesis and prevention of
hypertension saquelae (rats)
ENZYME INHIBITORS, ELASTASE INHIBITORS
ROIHL- 15979-05 Elastase. serum inhibitors and the
vasculature (human, swine)
P01HL19717-02 0003 Response of the lung to inju-y -
The role of elastolysis in emphysema (hamsters, rabbits)
POIHL 1971702 0016 Response of the lung to injury ■
The alveolar macrophage in elastase emphysema (guinea
pigs, hamsters)
ROIHL 20875-02 Chronic obstructive pulmonary disease-
l^amilial/genetic (human)
R23HL2243701 Leukotactrc mediators in lung
inflammatory reactions (rats, rabbits, human)
ROlHL-23595-01 Experimental emphysema -Depression of
protease inhibitors (rats, hamsters)
ENZYME INHIBITORS, MONOAMINE OXIDASE
INHIBITORS
ROlHL-12647 03 Inactivation of norepinephrine in vascular
tissue
POlHL-12738-10 0065 Physiologic pharmacology and its
clinical applications ■ Psychotheropeutic drugs and
cardiovascular system (human, rats)
POIHl 1625106 0007 Membrane-bound enzymes in heart
and other tissues - Flavins and flavoproteins
ROIHL 17487-04 Adrenergicvasoregulation interactions in
hypertension (human)
ROlHL-20194 01 Brain catecholamines in control of blood
pressure (rats)
R01HL-22039-02 Ion transport in cardiac muscle (dogs,
rodents, cattle)
202
ENZYME INHIBITORS, OXIDOREDUCTASE
INHIBITORS
ROlHL-10894-12 Intestinal bacteria and steroid
metabolism (human, guinea pigs, rabbits, rats)
ENZYME INHIBITORS, PHOSPHATASE
INHIBITORS
ROlHL-191 29-04 Cardiac glycosides -Mechanisms of
cellular actions
ENZYME INHIBITORS, PHOSPHODIESTERASE
INHIBITORS
POlHL-06285-18 0186 Cardiovascular-respiratory
physiology and biochemistry - Leukocyte hormone receptors
and cyclic nucleotides (tissue culture)
ROlHL-10897-12 Effects of hormones on cardiac
electrogenesis (rabbits, guinea pigs, dogs)
POlHL-1273810 0109 Physiologic pharmacology and its
clinical applications • Effects of calcium blockers on
skeletal and cardiac muscle (cats)
ROlHL-13306-08 Pharmacological control of cardiac
membrane currents (cattle, rabbits)
P50HL-1421807 0017 Pulmonary SCOR-Hewborn lung
center - Transvascuiar fluid exchange, vasoactive mediators
in ROS (sheep, cat)
POlHL-1583506 0018 Study of muscles related to heart
disease - Pharmacology of excitation coupling in muscle
(frog, barnacles)
ROIHL-15985-06 Metabolic and hormonal control of
cardiac contraction
** ROlHL-19062-03 Pharmacologic control of mast cell
phosphodiesterase (human, rats)
** ROlHL-19325-03 Phosphodiesterase inhibition and muscle
contraction
** ROlHL-22566-01 Mesolonic purinones as
phosphodiesterase inhibitors
ROlHL-23585-06 Pharmacologic control of hypersensitivity
phenomena (human)
ENZYME INHIBITORS, PROTEASE INHIBITORS
(GENERAL)
ROIHL 03180 21 Relation of lymphatics to
cardiopulmonary function (dogs)
P50HL14187-07 0014 Pulmonary SCOR -Chemical
mediators in pulrnonaiy vascular responses - Metabolism
and actions of vasoactive peptides in lung (human,
mammals)
P50HL-14192-08 0005 Specialized center of research in
hypertension - New techniques for recognition of
renovascular hypertension (human, dogs)
ROlHL-14262-07 Leukocyte proteases and their lung
targets (human, dogs, rabbits)
R01HL-14692-06 Alpha 1 antitrypsin deficiency and
pulmonary disease (human)
** R01HL-14700-05 Humoral and lung protease-antiproiease
role in obstructive disease (human)
ROlHL-14778-10 Proteolytic enzymes and inhibitors in
lung disease (mammals, human)
** ROlHL-15892-05 Inhibitors of proteinases (human, cattle,
swine)
ROIHL 15965 06 Experimental atherosclerosis and elastin
metabolism (chicks)
POlHL-16387-04 0008 The blood vessel and
thrombogenesis Factor Vlli in hemostasis (human,
rabbits)
RQlHL-16920-02 Proteases in normal and immunologically
injured lung (guinea pigs, rabbits)
ROlHL-186 18-04
kininogen
ROlHL-18625-03
(cattle)
** ROlHL-18679-04 Synthetic protease inhibitors
P50HL-18828-03 0001 Specialized center of research in
thrombosis - Membrane biology and hemostasis (human)
** P50HL-18828-03 0002 Specialized center of research in
thrombosis - Endothelial cell biology (human, guinea oig)
** P50HL-18828-03 0003 Specialized center of research in
thrombosis - Structure and function of plasma coagulation
inhibitors (human)
P50HL-1 88 28-03 0005 Specialized center of research in
thrombosis - Platelet inflammatory factors in thrombosis
(human, guinea pig)
ROlHL-19072-03 Modification of tissue injury in
myocardial infarction (dogs, human)
** ROlHL-19514-03 Proteinase inhibitor model with clinical
potential
" ROlHL-19721-03 Lung inflammation-Lysosomal proteases
and liposomes (human, rabbits)
ROlHL-20070-02
hamsters)
ROlHL-20199-02
in the rat
ROlHL-2028302 Maintenance of cellular integrity in
ischemic hearts (cats)
ROlHL-20337-02 Thromboembolic diseases (human)
POlHL-20552-02 0001 The development and regression of
cardiac hypertrophy - Biochemical events in cardiac
hypertrophy (rats)
Purification and function of human HMW
Organization of arterial ground substance
Alpha-lantitrypsin deficiency (human.
Drug-induced alterations in infarct size
ENZ
** POlHL-20994-02 0005 Dynamics of neutrophil elastase in
the lung - Protease inhibitors in pulmonary inflammation
and emphysema (rabbits)
** POlHL-20994-02 0006 Dynamics of neutrophil elastase in
the lung - Protease inhibitors in human bronchial mucus
ROlHL-21 11301 Control mechanisms in coagulation
(cattle)
R23HL-21411-02 Control of extracellular lysosomal
hydrolase levels (rats)
ROlHL-2 1540-02 Specific inhibitors of coagulation and
fibrinolysis (rats, rabbits, dogs)
R23HL-22799-01 Interaction of the complement and
coagulation systems (monkeys)
ROlHL-2289601 Immediate metabolic fates of kinlns and
angiotensins (rat, rabbit, guinea pig)
ROlHL-23211-01 Active normoxic pulmonary vasodilatation
(rat, dog, sheep)
*' ROlHL-23595-01 Experimental emphysema-Depression of
protease inhibitors (rats, hamsters)
ENZYME INHIBITORS, TRYPSIN INHIBITORS
P01HL06314-17 0051 Immunologic mechanisms in
cardiovascular disease Conformational studies of
phospholipid membranes and proteins
ROIHL 15817-06 Plasminogen activators from tissues
(human, pig. cattle)
ROlHl-15892-05 Inhibitors of proteinases (human, cattle.
swine)
ROIHL- 15979-05 Elastase, serum inhibitors and the
vasculature (human, swine)
POlHL-18577-03 0005 Lipoproteins-Cell surface
interactions - Chemical synthesis of apolipoproteins and
apoliprotein fragments
ROlHL-19514-03 Proteinase inhibitor model with clinical
potential
POlHL-20994-02 0006 Dynamics of neutrophil elastase in
the lung - Protease inhibitors in human bronchial mucus
ENZYME INHIBITORS, TRYPSIN INHIBITORS,
ANTITRYPSIN
ROlHL-04366-19 Plasminogen-Actlvation and structure-
function relations (mammals, birds)
ROlHL-09739-13 Biophysical studies of proteins (human)
*' ROIHL 14865-07 Biochemical studies on the pathogenesis
of emphysema (human, rats)
ROlHL-15125-07
in man
** ROlHL-15892-05
Molecular pathology of genetic disorders
Inhibitors of proteinases (human, cattle,
ROlHL-20666-02
(human)
POlHL-20994-02
lung
Cell biology of platelet preseivaiiun
Dynamics of neutrophil elastase in the
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
swine)
** ROlHL-16166-05 Structure of alpha-lantitrypsin in
relation to emphysema (human)
** ROlHL-17194-03 Comparison of two inherited forms of
alpha-lantitrypsin (human)
P01HL1743005 0005 Control of coagulation - The
activation of prothrombin (human, cattle, dogs)
P50HL- 18828-03 0001 Specialized center of research in
thrombosis - Membrane biology and hemostasis (human)
P50HL-1882803 0003 Specialized center of research in
thrombosis - Structure and function of plasma coagulation
inhibitors (human)
** ROlHL-18876-03 Human alpha-lantitrypsin synthesis in
vitro
P50HL-191 57-02 0008 Studies in cystic fibrosis and
bronchiolitis ■ Serum proteins in cystic fibrosis (human)
ROlHL-19777-03 Regulation of hypersensitivity In the lung
(rats, guinea pigs, rabbits, human)
** ROlHL-20070-02 Alpha-lantitrypsin deficiency (human,
hamsters)
M POlHL-20994-02 Dynamics of neutrophil elastase in the
lung
** POlHL-20994-02 0004 Dynamics of neutrophil elastase in
the lung - Mechanism of enzyme inhibition by alpha-1
antitrypsin (cattle)
POlHL-20994-02 0005 Dynamics of neutrophil elastase in
the lung - Protease inhibitors in pulmonary inflammation
and emphysema (rabbits)
ENZYME MECHANISMS
ROIHLO 19 74-24 Ion-pump In the erythrocyte (rabbits,
guinea pigs)
R01HL-01979-2Z Arteriosclerosis in zoo animals on
controlled diets (animals)
R01HL-02063-23 Biochemistry and function of lipids and
cell membranes (human, yeast, animals)
** ROlHL-02477-23 Biosynthesis and function of lipids
(microorganisms, rats)
ROlHL-02986-21 Zonal renal change with potassium
deficiency (rats, human)
ROlKL-03734-18 Metabolism of arterial tissue in
atherosclerosis (rabbits)
ROlHL-05209-18 Lipid metabolism (monkeys)
ROlHL-05360-19 Cholesterol biosynthesis and its control
in liver (rats)
POlHL-06285-18 0210 Cardiovascular-respiratory
physiology and biochemistry - Physicochemical and
enzymatic studies of lung surfactant (Halobacterium)
P01HL06308-18 0040 Mechanisms and therapy of
circulatory disease - Metabolism and fatty acid utilization-
Heart electrical stability (rats, dogs)
P01HL-06314-i7 0046 Immunologic mechanisms in
cardiovascular disease - Mediators of immune injury
(human, mice)
(contd)
ENZ
703
Immunologic mechanisms tn
Uangllcs and call biology
Immunologic machanisms in
Anilgans in caidiflviisculai dliaasa
poim 06314 w noib
cardlovijculai dijaase
POIHI 06314 U cos;
cardiovasculai disaasa
(human)
POIHI 07896 IS 0049 tnvironinantal biomedical lesaatch
piogiam Ellecis ol hypaibaric otygen and pmssuia on
caiebial eniymas (lalsl
POIHL 08214 IS 0041 Chemical and biological properties
of lipids Physico chemical regulation ol enqmes in lipid
metabolism
ROIHL 08634 IS En;ymic cholesterol synthesis (human.
rats, protoioa. yeast)
POIHL 08899 14 OOSS Tolerance to respiratory gases in
health and disease Oxygen attects on organ (unctions
Extension of tolerance
POIHL 09011 IS 0021 A research and resource program
in blood Regulation ol transfer RNA methylating en/ymes
(rats, E coll)
R01HL-0912S-U Ultrastructural cytochemistry (human,
chick)
ROIHL 10894 12 Intestinal bacteria and steroid
metabolism (human, guinea pigs, rabbits, rats)
POIHL'11310'12 0096 Mechanisms of cardiovascular
disease - Complement chemistry anci biology (human,
rabbits)
POIHL 113S1 12 0019 Cellular and molecular
mechanisms of myocardial function - Mechano-chemical
kinetics of small perturbations
ROIHL'11614'11 Trace elements in nutrition (chickens,
rats, human)
ROIHL'11802 10 Cardiovascular surgical research (dogs,
sheep, swine, cats, monkeys)
ROIHL'12138'08 Nutritional regulation of enzyme activity
(rats, human)
POIHL 12373 10 0006 Cardiopulmonary physiology and
pathophysiology Fatty acid metabolism -Regulation.
implications (human, mammals, birds)
P01HL12373-10 0012 Cardiopulmonary physiology and
pathophysiology - Biochemistry of the sympathetic nervous
system (rats, rabbits, pigeons)
ROlHL-12647 08 Inactivation of norepinephrine in vascular
tissue
' ROlHL-1268409 Angiotensin I and converting enzyme in
hypertension (human, primates, dogs)
R01HL'1274S'10 Enzymes and inhibitors of cholesterol
biosynthesis (rats, human, swine)
' ROlHL'12944-09 Enzymatic and biochemical studies on
blood cells (human)
ROlHL-1319309 athophysiology of posttraumatic and
shock states (rodents, dogs)
P01HL13262 07 0015 Arterial wall in atherosclerosis ■
Crosslinkage biosynthesis in aortic elastin and collagen
(animals)
R01HL13302-09 Uptake and metabolism of lipids by the
liver (rats)
R01HL13630-08
(cattle)
* ROlHL-1372208
rabbits, human)
P50HL1413805 0014 Center for research on
atherosclerosis - Core biostatistics laboratory
P50HL-14138 05 0015 Center for research on
atherosclerosis - Arterial wall-Intermediary metabolism,
enzyme activity and bioenergetics
P50HL14141-05 0003 SCOR for atherosclerosis in
childhood • Detection of abnormalities in lipid metabolism
(human, rabbits, rats)
P50HL-14192-08 0004 Specialized center of research in
hypertension - Isolation and characterization of pure renin
(swine, rats, human, rabbits)
P50HL1421407 0015 Newborn lung center for hyaline
membrane disease ■ Hormone effect on cyclic nucleotide
lipid synthesis in developing lung (animal)
P50HL-14217-08 0058 Specialized center of research in
thrombosis - Mechanisms of induction and inhibition of
platelet reaction (human, pig)
P50HL-14218-07 0017 Pulmonary SCOR-Newborn lung
center - Transvascular fluid exchange, vasoactive mediators
in ROS (sheep, cat)
* P50HL-I423707 0002 Support for arteriosclerosis center
- Interactions of lipoprotein particles with vascular surface
(human, rat)
ROlHL-1426207 Leukocyte proteases and their lung
targets (human, dugs, rabbits)
* P01HL1438807 0173 Regulation of the circulation in
pathological states - Mechanisms of cardiac myosin ATPase
R01HL-1439,'-07 Hypertension-Angiotensin and
prostaglandin ph;Kniacology (animals)
POlHL-14414-07 0014 Environmental influences on
cardiorespiratory and cellular functions - Temperature and
acid-base status in tissues, cells, and subcellular system
POIHL-14414-07 0016 Environmental influences on
cardiorespiratory and cellular functions - Effects of
pressure on membrane and cellular function (human,
rabbits)
* ROlHL-14456-07 Lung metabolism-Enzymes in the
pulmonary circulation (human, animals)
R01HL-14509-07 Hypertension-Chemistry and biophysics
of angiotensin
ROlHL'14700-05 Humoral and lung protease-antiprotease
role in obstructive disease (human)
Platolet prostaglandins (human, rabbili)
Lipid transport in avian species
Control of glycogen synthesis in heart
Acid and alkaline lipases in aortas (rats.
ROIHL 14890 0/
ROIHI 14990 0/
(chickens)
ROIHI 14992 0/ Mechanism of Ihrombin action (human)
PSOHL 15062 0/ 0008 Study of lipopioteins, artery wall.
and atherosclerosis Lipid modilying en/ymes (human.
monkey)
P60HL ISI/OOS 001/ Support foi cenlei for sickle cell
anemia Control of hemoglobulin synthesis (human)
ROIHL 1S3/6 06 Intermediary metabolism of sterols (mice)
ROIHL ISSe/OS Cardiovascular phosphoinositido
metabolism (rats)
POIHL 15832 06 0001 Chemical structural predispositions
10 lung iniury Chemical composition of lung connective
tissue proteins (human, animals)
POIHI 1583206 0002 Chemical structural predispositions
to lung injury Connective tissue in lung in development
and repaii of in|ury (human, rats, mice)
POIHL 1583206 0004 Chemical structural predispositions
to lung injury Proteolytic activity leucocytes in patients
with obstructive lung disease
POIHL 1583206 0008 Chemical structural predispositions
to lung injury Interstitial fibrosis-Connective tissue
components in normal and diseased lungs
POIHI 1583206 0009 Chcmii-al structural predispositions
to lung injury Immunology Enzyme degradation products
of human lung elastin and microfibril
POIHL 1583206 9001 Chemical structural predispositions
to lung injury - Tissue culture studies of lung cell function
•Core facility
ROIHL 15887 OS Enzymes of blood coagulation and
fibrinolysis (human)
R01HL1597905 Elastase, serum inhibitors and the
vasculature (human, swine)
P60HL 15999-05 0021 Miami comprehensive sickle cell
center Diphosphonates Erythrocyte calcium loading,
maturation (human, chick embryo)
ROlHL-16101-05 Protein-lipid interaction (bacteria,
models)
P01HL16251 06 Membrane bound enzymes in heart and
other tissues
P01HL16251-06 0002 Membrane-bound enzymes in heart
and other tissues - Structural basis of regulation of
cardiac succinate dehydrogenase
' P01HL16251-06 0003 Membrane-bound enzymes in heart
and other tissues - Regulation of cardiac succinate
dehydrogenase (yeasts, mammals)
POlHL-16251-06 0007 Membrane-bound enzymes in heart
and other tissues - Flavins and flavoprotems
' POlHL-16251-06 0008 Membrane-bound enzymes in heart
and other tissues - Iron-sulfur centers and phospholipids
modulation of succinate dehydrogenase
POlHL-16251-06 0009 Membrane-bound enzymes in heart
and other tissues - NADH dehydrogenase and site I of
oxidative phosphorylation (yeast)
* POlHL-16251-06 0010 Membrane-bound enzymes in heart
and other tissues - Reversible activation of L-amino acid
oxidase (snakes)
ROlHL-16294-04 Effectors of cholesterol synthesis (rats)
' ROlHL-16346-09 Enzyme assay for blood clotting (human)
* ROlHL-16364-04 Regulation of lipid biosynthesis and
transport (rats, swine, Xenopus)
R01HL-18577-04 Lipoprotein lipase chemistry and function
(rats, cattle, human)
ROlHL-16588-05 Collagen synthesis in atherosclerosis
(dogs, rats, rabbits, human)
ROlHL-16628-05 Regulation of lipid metabolism (rats)
ROlHL-16634-13 Regulation of metabolism in fibroblasts
and platelets (human, rabbits, sheep)
* ROlHL-16647-05 Studies on the control of sickle cell crisis
(human)
ROlHL-167 14-05 Endothelial cell communication in
homeostasis (human, mammals)
ROlHL-16768-04 The sympathetic nervous system and the
arterial wall (rabbits, pigeons)
POlHL-16769-05 0002 Pathobiologic and host defense
reactions in the lung - Pathogenesis of complement
dependent injury to the lungs (rabbits)
ROlHL-16796-05 Cholesterol regulation by HMG-CoA
reductase (rats, human)
POlHL-16833-04 0016 Hemoglobin and red cell system in
hemoglobinopathies - Calcium-indiced membrane damage
in Hb SS disease (human, animals)
* P60HL-17269-04 0003 National heart and blood vessel
research and demonstration center - Atherosclerosis -Fatty
acid metabolism in cardiovascular tissue (human, chicken)
* P60HL-17269-04 0015 National heart and blood vessel
research and demonstration center - Lipoprotein
metabolism laboratory (human)
P60HL-17269-04 0017 National heart and blood vessel
research and demonstration center - Cell membrane (dogs,
rabbits)
ROlHL-17332-04 Use of the gut tor therapy of coronary
artery disease (mammals)
* ROlHL-17371-05 Regualtion of cholesteryl ester levels in
the aorta (swine)
ROlHL-17437-03 'Perfusion lung'-Role of traumatized
leukocytes (dogs, human)
R01HL-17462-03 Role of glycosphingolipids in platelet
aggregation (rats, human, dogs)
ROlHL-17551-04 Biosynthesis and metabolism of
procollagen (human, monkeys, mice)
km
HO I HI I/S96 03 Laukocytt •ndothilial inlaraclwnt (rait)
HOIHI 1/59/ 05 Holt of plasma lipopfoltini in
alherosLkiosis (swini*. human)
KUIHL 1/623 05 Initial tvanis in Ihrombui formation on
surfaces (human, rail)
PSOHI 1/648 04 0023 Study of ItclMinlc htart dttMM
Chiimical mediators of inflammation in acuta myocardial
infarction (mammals)
P50H1 1/648 04 002/ Study of ischamic heart diseata
Phospholipid mitabolism following cardiac injury and
repair (rat)
PSOHL 1766/ 04 0012 Study of ischemic heart dIsaaM
Biochemistry of normal and ischemic heart Glycolysis (rats)
P50HL 1/682 04 0018 Study of ischemic heart disease
Biochemistry of ischemia Heart cell and organ culture
(mice. rats, cattle)
ROIHL 17719 03 Lung injury, substrate utilization, oxygen
toxicity (rats, rabbits, dogs)
ROIHL 1/729 04 Stimulus response coupling in platelets
(human)
ROIHL 17783 04 Complex carbohydrates Structure,
function, synthesis (swine)
ROlHl-1788704 Regulation of HMG COA reductase and
sterol synthesis (human, mammals)
ROIHL 17976 18 Chemical agents and heart glycolytic
enzymes (sheep)
ROlHL-18089 04 Fatty acid metabolism in heart and its
regulation (swine, rats)
ROIHL 18094 04 Regulation of cholesterol biosynthesis
(rats)
' ROIHL 18157 04 Subcellular events in atherosclerosis
(human, rabbits, calves)
ROIHL 18181 04 Surfactant metabolism- Alveolar cells and
lung disease (mice, rabbits)
POIHL 18208-04 0001 Center for the study of blood cell
rheology Physiological basis of reversible erythrocyte
shape change (human, firefly)
ROIHL 18219-04 Regulation of cholesterol metabolism
(rats)
ROIHL 18288 04 Intraoperative protection of the
myocardium (dogs, rats)
ROlHL-18340-04 Electron microscopy of the
juxtaglomerular apparatus (rats)
ROlHL-18460-01 Effects of prolonged hypoperfusion on the
myocardium (rabbits)
ROlHL-18502-03 Enzymatic regulation of platelet function
(human)
ROlHL-18527-03 Subcellular response of heart to
functional overload (hamsters, rats)
ROlHL-18560-03 Cardiovascular adaptation to stress
(miniature swine)
POlHL-18574-03 0005 Lipoprotein methodology and
biomedical applications - Structure and function of
lipoproteins
POlHL-18575-03 0001 Mechanisms of vascular changes
in hypertension - Arteries and resistance vessels in
hypertension (pigs, rats)
ROlHL-18618-04 Purification and function of human HMW
kininogen
ROlHL-18647-03
heart cells (rats)
ROlHL-18723-03 Genetic heterogeneity of acid lipase-
Atherosclerosis (human)
ROlHL-18764-03 Biosorbable thromboresistant surfaces
(dogs. rats, swine, human)
ROlHL-18825-04 Interaction of peptides and target cells
in lung (human)
* P50HL-18828-03 0003 Specialized center of research in
thrombosis - Structure and function of plasma coagulation
inhibitors (human)
ROlHL-18908 03
serum
ROlHL-18936-02
studies (rat)
ROlHL-18938-03
metabolism (rats)
ROlHL-19000-03 Irreversible myocardial injury (rats)
ROlHL-19010-03 Metabolism and cell biology of lung
surfactant system (rabbits, sheep)
ROlHL-19063-03 Cholesterol and lipoprotein metabolism
(rat hepatocytes)
R01HL-19077-01 Biochemistry and molecular biology of
sarcoidosis (human, rabbits)
ROlHL-19129-04 Cardiac glycosides-Mechanisms of
cellular actions
ROlHL-19132-04 Role of zinc transferrin in lymphocyte
transformation (human)
ROlHL-19148-03 Myocardial organelle lipid structure and
function (dog, rat)
ROlHL-19223-03 Control of cholesterogenesis in leukocytes
and liver (rats, human)
ROlHL-19237-03 Obstructive lung disease and alveolar
macrophages (human, animals)
POlHL-19242-02 0001 Study of vascular smooth muscle -
Energy metabolism and protein turnover in vascular smooth
muscle (rats)
>* ROlHL-19250-03 Mechanism of plasma cholesterol
esterificaticn (human)
R23HL-19605 01 Lipid requirement of the lung mono-
oxygenase system (rabbits)
POlHL-19717-02 0001 Response of the lung to injury -
Lung elastic tissue (animals)
(contd)
Ischemic myocardial injury in cultured
Angiotensin converting enzyme of human
Heart preservation and transplantation
Pulmonary fatty acid and phospholipid
'Excludes routine methodology OR covei^ only general projects which preclude indexing at the specific level.
**Cnented significantly to above subject.
M Grant has subprojects deschbing specific research aspects.
See Appendix for investigator's name and grant number.
fw fir j'wT^Mf^M" rf" .-■
ENZ
Cryopreservation of the isolated heart
Genetics of glycosyltransferases in
* P01HL-197I7-02 0002 Response of the lung to injuiy -
Prolyl hydroxylase, lysyl hydroxylase and lung collagen
biosynthesis (rabbits)
P01HL1971702 0003 Response of the lung to injuiy -
The role of elastolysis in emphysema (hamsters, rabbits)
* P01HL19717-02 0004 Response of the lung to injury -
Regulatory and physical-chemical properties of lung lysyl
oxidase (animals)
* POlHL-1971702 0022 Response of the lung to injury •
Localization of enzymes and sites of action in experimental
emphysema (hamsters)
POlHL-19737-02 0005 Cellular and molecular aspects of
respiratory physiology - Interaction of respiratory exchanges
and blood gas parameters (human, animals)
ROlHL-20143-02 Hypothermic circulatory arrest -Cerebral
vascular change (dogs)
ROlHL-20199-02 Drug-induced alterations in infarct size
in the rat
ROlHL-202 19-02
(rats)
ROlHL-20301-02
human blood
ROlHL-20408-03 Hyperlipidemia in diabetics during
muscular training (human)
ROlHL-20794-02 Prostaglandin synthesis in human
platelets (also in sheep, rabbit)
ROlHL-20846-02 Purification of bovine plasminogen
proactivator
ROlHL-20875-02 Chronic obstructive pulmonary disease-
Familial/genetic (human)
R01HL-20878-02 Cellular aspects of lung injury (rats,
rabbits)
ROlHL-20925-01 The acetylation of fetal hemoglobin
(human)
POlHL-20948-02 0001 Molecular basis of cholesterol
metabolism - Biochemical and ultrastructural
characterization of LDL In human fibroblasts
POlHL-20993-02 0006 Population dynamics of arterial
cells in atherogenesis - Mechanism of regression of
atherosclerosis by diet and injury (swine)
POlHL-20994-02 0004 Dynamics of neutrophil elastase in
the lung - Mechanism of enzyme inhibition by alpha-1
antitrypsin (cattle)
■ POlHL-20994-02 0007 Dynamics of neutrophil elastase in
the lung - The etiology of experimental emphysema (dogs)
ROlHL-21009-02 Effects of air pollutants on lung cells in
culture (rats)
R23HL-21 116-02 Mechanisms of membrane and tissue
damage In lung (dogs, rabbits)
' R23HL-21189-01 Regulation of pulmonary endothelial cell
activities (human, cattle)
R23HL-21225-02 Connective tissue precursor molecules in
the lung (rabbits, hamsters)
R23HL-21271-02 Extracorporeal circulation and protein
denaturation (human)
' R01HL-2I274-01 Prorenin-Physiological and biochemical
analysis (human)
R23HL-21327-02 Molecular mechanisms of chemical
myocardiopathies (rats)
ROlHL-21394-02 Pulmonary angiotensin-converting enzyme
(rabbits)
R23HL-21421-01 Myocardial and vascular contractility and
cyclic nucleotides (cattle, rats)
ROIHL-21480-01 Structure, source and functions of
alveolar glycoproteins (human, rabbits)
ROlHL-21628-02 Biosynthesis of lung surfactant lipid
(rabbit)
ROlHL-21874-01
R23HL-21894-01
(cattle)
ROlHL-21996-01 Alteration of digitalis and aldosterone
disposition (rats, rabbits, mice, dogs)
ROlHL-22053-02 The disordered lipid metabolism of
diabetes mellitus (chickens, mammals, human)
R23HL-22075-01 Metabolism of arachidonic acid in blood
vessels (chickens, mammals)
ROlHL-22088-02 Metabolic basis for diabetic
microangiopathy (cattle)
ROlHL-22121-02 Dyslipoproteinemia in diabetes and
vascular disease (human)
ROIHL 22242-01 The converting enzyme of lung (cattle.
human)
ROlHL-22259-01
poisoning (rats)
R23HL-22346-01 Hematological injury and pulmonary
dysfunction (human, mammals)
ROlHL-2238701 Metalloenzymes and disease
R23HL-22437-01 Leukotactic mediators in lung
inflammatory reactions (rats, rabbits, human)
ROlHt.-22486-Ol Enzyme regulation in cultured arterial
cells (swine)
R01HL-22500-01 Conversion of choline to
phosphatidylcholine in lung (rabbits, pigs)
ROlHL-22530-01 Active site studies on blood proteases
(human)
R01HI.-22651-01
muscle
ROlHL-22875-01
SRSA-lts biosynthesis and action
Pulmonary angiotensin converting enzyme
Modification of susceptibility to oxygen
Control of protein metabolism in heart
Crotalase -Chemistry, physiology, clinical
potential (rats, rabbits)
ROlHL-22924-01 The airway mucosal barrier (guinea pigs)
ROlHL-22967-01 Structure and function of heparin
releasable lipases (swine, human)
204
R01HL-23013-01 Smooth muscle development in vitro
(chick embiyo)
ROlHL-23249-01 Actin-myosin interaction in pulmonary
smooth muscle (cattle)
ROIHL 23618-01 Substrate metabolism in isolated
myocytes in shock (dogs, rats, guinea pigs)
ROlHL-23969-01 Surfactant synthesis by type II cells in
vitro (rats)
ROlHL-23981-01 Acute alveolar injuiy (dogs)
ENZYME MODELS
P50HL- 14 147-08 0013 Specialized center of research in
thrombosis - Mathematical models of blood coagulation
kinetics
ENZYME RECONSTITUTION
ROlHL-12576-10 Bioenergetics apparatus in heart
mitochondria
ROlHL-136 19-09 Microsomal electron transport in liver
and heart (human, mammals)
R01HL-I8905-04 Acquisition of native conformation of
proteins (human, cattle)
ENZYME REPRESSION
SEE ENZYME INDUCTION REPRESSION-DEREPRESSION
ENZYME STRUCTURE
ROlHL-02033-23 Regulation of cholesterol esters in blood
and tissues (rat, cattle, human)
ROlHL-04366-19 Plasminogen -Activation and structure-
function relations (mammals, birds)
POlHL-0821415 0027 Chemical and biological properties
of lipids - Biological functions diol lipids (swine, rats,
plants)
ROlHL-08893-14 Structure and function of membrane
proteins (human)
P01HL-U3 10-12 0096 Mechanisms of cardiovascular
disease - Complement chemistry and biology (human,
rabbits)
** ROlHL-1258510 Structural properties of malate
dehydrogenase (swine)
ROIHL- 136 30-08 Control of glycogen synthesis in heart
(cattle)
P50HL-14153-07 0015 Johns Hopkins Lung Center-
Chronic diseases of airways - Kinins and human lung
P50HL-14187-07 0014 Pulmonary SCOR -Chemical
mediators in pulmonary vascular responses Metabolism
and actions of vasoactive peptides in lung (human,
mammals)
ROlHL-14262-07 Leukocyte proteases and their lung
targets (human, dogs, rabbits)
ROlHL-1477810 Proteolytic enzymes and inhibitors in
lung disease (mammals, human)
ROlHL-14990-07 Lipid transport in avian species
(chickens)
P50HL- 15062-07 0001 Study of lipoproteins, artery wall.
and atherosclerosis - Structure and molecular interactions
of serum lipoproteins (human, monkey)
** P50HL-15062-07 0008 Study of lipoproteins, artery wall,
and atherosclerosis - Lipid modifying enzymes (human.
monkey)
** ROlHL-15125-07 Molecular pathology of genetic disorders
in man
ROlHL-16101-05
models)
POlHL-16251-06 0001 Membrane-bound enzymes in heart
and other tissues - Structure of covalently bound flavins
(bacteria, yeast, mammals)
POlHL-16251-06 0002 Membrane-bound enzymes in heart
and other tissues - Structural basis of regulation of
cardiac succinate dehydrogenase
** ROIHL 16686-04 Properties of cytochrome oxidase (cattle.
bacteria)
ROlHL-16796-05 Cholesterol regulation by HMG-CoA
reductase (rats, human)
P60HL-17269-04 0003 National heart and blood vessel
research and demonstration center - Atherosclerosis -Fatty
acid metabolism in cardiovascular tissue (human, chicken)
ROlHL-17371-05 Regualtion of cholesteiyl ester levels in
the aorta (swine)
** R01HL-17559-03 Structural elucidation of heart
cytochrome-C oxidase
ROlHL-17783-04 Complex carbohydrates-Structure,
function, synthesis (swine)
R01HL17879-04 Molecular structure of the ouabain
sensitive ATPase (dogs)
ROlHL-17963-04 Human erythrocyte carbonic anhydrase
** R01HL17976-18 Chemical agents and heart glycolytic
enzymes (sheep)
ROIHL 1800305 Digitalis-Mechanism and reversal studies
(dog, sheep, duck, guinea pig, human)
ROlHL-18089-04 Fatty acid metabolism in heart and its
regulation (swine, rats)
** R01HL18094-04 Regulation of cholesterol biosynthesis
(rats)
** ROlHL-18095-04 Human dopamine-betahydroxylase (also
cattle)
POIHL- 182 08-04 0007 Center for the study of blood cell
rheology ■ RBC membrane protein (human)
ROlHL-18272-03 Heart adenyl cyclase complex (beef
heart)
" P50HL-1882803 0003 Specialized center of research in
thrombosis - Structure and function of plasma coagulation
inhibitors (human)
Protein-lipid interaction (bacteria.
ENZ
ROlHL-18905-04 Acquisition of native conformation of
proteins (human, cattle)
ROlHL-18908-03 Angiotensin converting enzyme of human
serum
Experimental neurogenic
Biochemistry of brain tyrosine
POlHL-18974-03 0009
hypertension program
hydroxylase (rats)
POlHL-18974-03 0010
hypertension program
PNMT in brain (rats)
POlHL-18974-03 0011
hypertension program
Experimental neurogenic
Biochemistry and regulation of
Spectroscopic studies of respiratory
Proteinase inhibitor model with clinical
Genetics of glycosyltransferases in
'Excludes routine methodokiey OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to atwve subject.
Experimental neurogenic
Biochemistry and regulation of
brain tryptophane hydroxylase (rats)
P01HL18974-03 0015 Experimental neurogenic
hypertension program - Neurochemistry core
ROlHL-19392-03
metalloproteins
ROlHL-19514-03
potential
ROIHL 20116-01 Heart lactate dehydrogenase-The complex
with NADH (pig)
** ROlHL-20301-02
human blood
ROIHL 20658-01 Myocardial energy transport-Creative
kinase (human, cattle, dog)
ROlHL-20794-02 Prostaglandin synthesis in human
platelets (also in sheep, rabbit)
ROlHL-21095-02 Enzymes of M tuberculosis and
obstructive lung disease (human, rodents)
R23HL-21 11602 Mechanisms of membrane and tissue
damage in lung (dogs, rabbits)
ROlHL-2 1394-02 Pulmonary angiotensin-converting enzyme
(rabbits)
R23HL 21411-02 Control of extracellular lysosomal
hydrolase levels (rats)
R23HL-21894-01 Pulmonary angiotensin converting enzyme
(cattle)
** ROlHL-22050-01 Organization of succinic oxidase in heart
ROIHL-22174-01 Assembly of membranes in heart and
yeast mitochondria
ROlHL-22242-01 The converting enzyme of lung (cattle.
human)
ROlHL-22265-02 Isozymes of heart glutamate aspartate
transaminase (swine, ducks)
** ROlHL-22530-01 Active site studies on blood proteases
(human)
** POlHL-22619-01 0011 Cellular mechanisms of heart
failure - Reaction of lipoproteins and apollpoprotelns with
lipoprotein lipase (cattle)
ROlHL-22875-01 Crotalase-Chemistry. physiology, clinical
potential (rats, rabbits)
" ROlHL-22967-01 Structure and function of heparin
releasable lipases (swine, human)
R23HL-22984-01 Cyclic AMP dependent protein kinases in
hypertension (rat)
ROlHL-23615-01 Biochemistry of contractile proteins
(chicken, rabbit)
ENZYME SUBSTRATE
** POlHL-06285-18 0134 Cardiovascular-respiratory
physiology and biochemistry - Placental transfer in growth
retarded fetuses (lambs)
POlHL-07896-15 0049 Environmental biomedical research
program - Effects of hyperbaric oxygen and pressure on
cerebral enzymes (rats)
ROlHL-08659-14 Myocardial performance and metabolism
in the newborn (sheep)
POlHL-08682-15 0020 Regulation of the cardiovascular
system - Hepatic metabolic basis of shock (rat)
POlHL-1 1310-12 0080 Mechanisms of cardiovascular
disease - Metabolism of the hypertrophied myocardium
(human)
POlHL-1 1310-12 0096 Mechanisms of cardiovascular
disease - Complement chemistry and biology (human,
rabbits)
POlHL-11310-12 0104 Mechanisms of cardiovascular
disease ■ Structure of connective tissue proteoglycans
(rabbits)
ROlHL-11614-11 Trace elements in nutrition (chickens,
rats, human)
POlHL-12373-10 0006 Cardiopulmonary physiology and
pathophysiology - Fatty acid metabolism-Regulation,
implications (human, mammals, birds)
ROlHL-13160-08 Human thrombin (also cattle)
ROlHL-13722-08 Acid and alkaline lipases in aortas (rats.
rabbits, human)
P50HL-14214-07 0015 Newborn lung center for hyaline
membrane disease - Hormone effect on cyclic nucteotide
lipid synthesis in developing lung (animal)
P50HL-14237-07 0002 Support for arteriosclerosis center
- Interactions of lipoprotein particles with vascular surface
(human, rat)
P50HL-15062-07 0001 Study of lipoproteins, artery wall,
and atherosclerosis - Structure and molecular interactions
of serum lipoproteins (human, monkey)
ROlHL-16634-13 Regulation of metabolism in fibroblasts
and platelets (human, rabbits, sheep)
P60HL- 17269-04 0015 National heart and blood vessel
research and demonstration center - Lipoprotein
metabolism laboratory (human)
P50HL-17667-04 0012 Study of ischemic heart disease ■
Biochemistry of normal and ischemic heart-Glycolysis (rats)
(contd)
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
ENZ
PiOHL 17670 04 0022 Study ot ischtmic heart dl»is«
Myociidlil inttibollsm in hypoiit and lecovai (labbit,
toad. do|)
ROIHL 1808S04 Fatty acid malabolism in h«ait and its
i«|ulation (swina. lats)
ROIHL 18143 03 Suigeiy and pulmonary tissue alteiations
(do(s. lats, tiuman)
ROIHL 18!i61 03 Radioimmunoassay ol sngiotensinogen
(l)umanl
ROIHL 20388 03
lieail (rat)
ROIHL 21140 01 Studies o( pulmonay alveolar
macroptiage function (rabbits)
ROIHL 2120902 Alterations at metabolism in Iscliemic
myocardium (swine)
R23HL 21393 01
(rats)
Regulation ot protein turnover in diabetic
R23HL2189401
(cattle)
ROIHL 2224201
human)
ROIHL 2253001
(human)
R23HL-22818 01
Cardiac adaptation to aging and stress
Pulmonary angiotensin converting enzyme
The converting enzyme ol lung (cattle.
Active site studies on blood proteases
Biosynthesis ol human respiratory
mucous glycoprotein (also dog)
R23HL 22984 01 Cyclic AMP dependent protein kinases in
hypertension (rat)
ROIHL'23161'01 0001 Biology ot myocardial ischemia
Mitochondrial lipid metabolism and cardiac ischemia (rat.
dog)
ENZYME SUBSTRATE COMPLEX
ROIHL'01662 25 Equilibria in the fibrinogenfibrin
conversion (human, cattle)
P50HL-1506207 0008 Study o( lipoproteins, artery wall.
and atherosclerosis - Lipid modifying enzymes (human.
monkey)
R01HL1608705 Structural and dynamic study of model
heme completes (yeast)
R01HL17462 03 Role ot glycosphingolipids in platelet
aggregation (rats, human, dogs)
POlHL-1781204 0001 Thrombosis and plasma proteins ■
Thrombosis and plasma proteins (cattle, guinea pigs)
ROlHL-17963-04 Human erythrocyte carbonic anhydrase
R01HL18272-03 Heart adenyl cyclase complex (beef
heart)
** P50HL 1882803 0003 Specialized center of research in
thrombosis - Structure and function of plasma coagulation
inhibitors (human)
** ROlHL-201 16-01 Heart lactate dehydrogenase-The complex
with NAOH (pig)
ROlHL-20658-01 Myocardial energy transport-Creative
kinase (human, cattle, dog)
R23HL-2 14 11-02 Control of extracellular lysosomal
hydrolase levels (rats)
ROlHL-22265-02 Isozymes of heart glutamate aspartate
transaminase (swine, ducks)
ROlHL-23161-01 0003 Biology of myocardial ischemia -
Phosphorylase coupling to myocardial sarcoplasmic
reticulum (dog)
ENZYME THERAPY
SEE ALSO GENETIC DISORDERS. GENE THERAPY
ROlHL-19721-03 Lung inflammation -Lysosomal proteases
and liposomes (human, rabbits)
ROlHL-19779-03 Biochemical basis of oxygen damage to
lung cells (guinea pigs, rats)
ROlHL-21115-01 Prevention of 02 toxicity with superoxide
dismutase (rats)
ENZYMES
SEE ALSO ALDOLASES
SEE ALSO AMIDINOTRANSFERASES
SEE ALSO AMINOHYDROUSES
SEE ALSO BIOLOGICAL TRANSPORT. TRANSPORT PROTEINS.
PERMEASES
SEE ALSO CARBOHYDRASES
SEE ALSO CHEMICAL REACTIONS. CATALYSTS
SEE ALSO CHOLINE ESTERASES
SEE ALSO COENZYMES
SEE ALSO DEHYDRATASES
SEE ALSO ENZYME INHIBITORS
SEE ALSO ESTERASES
SEE ALSO HEMOPROTEINS. CYTOCHROME
SEE ALSO HYOROUSES
SEE ALSO ISOMERASES
SEE ALSO LIGASES
SEE ALSO LIPASES
SEE ALSO LIPID MOBILIZING FACTORS
SEE ALSO METALLOPROTEINS, FERREDOXIN
SEE ALSO NUCLEASES
SEE ALSO OXIDOREDUCTASES
SEE ALSO OXYGENASES
SEE ALSO PANCREAS. PANCREATIC ENZYMES
SEE ALSO PEROXIDASES
SEE ALSO PHOSPHATASES
SEE ALSO PHOSPHORYLASES
SEE ALSO PROTEASES AND PEPTIDASES
SEE ALSO RESPIRATORY PROTEINS, RESPIRATORY ENZYMES
SEE ALSO TRANSACYUSES
SEE ALSO TRANSFERASES
** P01HL-063U-17 0055 Immunologic mechanisms in
cardiovascular disease - Genetics and cell biology
aos
POIHl 15837 06 0010 Chemical structural predispositions
to lung injury Kinin genemting systems in pulmonary
disease (human, animals)
POIHL 16769 05 0011 Pathobiologic and host defense
reactions in the lung Core Laboratory lor biomedical
preparation (rabbits)
P50HL 1/669 04 0011 Ischemic heart disease center
(SCOR) Lysosomal function and lysosomal enzymes in
normal and ischemic heart (rabbit)
ROIHL 18554 03 Taurine metabolism in mammalian heart
(rodents, cattle, swine)
ROIHL 20909 02 Clolibrata enhanced lipid oxidation by
peroxisomes (rats)
ENZYMES, APOENZYMES
ROIHL 11511 10 Structure of ferritin and its role in iron
metabolism (horse, rats, human)
ENZYMES, EXOENZYMES
*• R01HL21095 02 Enzymes of M tuberculosis and
obstructive lung disease (human, rodents)
R23HL 2 14 1 1 02 Control ol extracellular lysosomal
hydrolase levels (rats)
ENZYMES, FETAL ENZYMES
ROIHL 2007002 Alpha 1 antitrypsin deficiency (human,
hamsters)
ENZYMES, HYBRID ENZYMES
ROIHL 1562805 Regulation of lipid metabolism (rats)
ENZYMES, ISOENZYMES
SEE ALSO ENZYMES. FETAL ENZYMES
POIHL 031 74 23 0006 Mechanisms of acute vascular
reaction to injury Atherosclerotic plaque studies using
mosaic analysis (human)
P01HL06285-18 0164 Cardiovascular-respiratory
physiology and biochemistry CPK MB isoenzyme
concentration to quantify infarct size (human, animals)
** POlHL-06312 17 0053 Surgical cardiology - Enzyme
pattern following cardiac surgery (human)
ROIHLI 16 14-11 Trace elements in nutrition (chickens.
rats, human)
POIHL 12157-11 0055 Functions and mechanisms of cell
membrane ion transport - Growth and development of
synthetic strand heart cells in culture (chick embryo)
** ROlHL-12585-10 Structural properties of malate
dehydrogenase (swine)
ROlHL-12690-09 Systemic and local vascular adjustment
in shock (monkeys, cats)
R01HL-1362e-06 Lipoprotein lipase and lipoprotein
removal (human, rats, bacteria)
P50HL-14192-08 0004 Specialized center of research in
hypertension - Isolation and characterization of pure renin
(swine, rats, human, rabbits)
ROIHL 15002-07 Biochemical pharmacology of guanylate
cyclase in lung (cattle, rats)
ROlHL-151 25-07 Molecular pathology of genetic disorders
in man
ROlHL-16254-05 Pathogenesis of bubble and clot
formation (fish)
" P50HL-17646-04 0005 Study of ischemic heart disease -
Biochemical markers and mediators of myocardial ischemic
injury
P50HL- 17546-04 0006 Study of ischemic heart disease -
Mathematical models for predicting infarct size using CPK
and other markers
** P50HL-17646-04 0007 Study of ischemic heart disease -
Prediction of myocardial ischemic injury by analysis of
plasma CPK isoenzymes
P50HL-17648-04 0023 Study of ischemic heart disease -
Chemical mediators of inflammation in acute myocardial
infarction (mammals)
P50HL17651-04 0039 Ischemic heart disease specialized
center of research - Measurement and prediction of infarct
size (human, dog)
** P50HL-17665-04 0008 Study of ischemic heart disease -
Core laboratory-CPK isoenzyme measurement and
myocardial necrosis evaluation
** P50HL-1766704 0043 Study of ischemic heart disease -
Quantitation of myocardial infarct size by serial enzyme
measurements (human)
P50HL17559-04 0001 Ischemic heart disease center
(SCOR) - Radioimmunoassays for CPK isoenzyme and
myoglobin (human, dog)
P50HL-17559-04 0023 Ischemic heart disease center
(SCOR) - Patients with acute myocardial infarction and
myocardial ischemia (human)
** P50HL- 176 70-04 0017 Study of ischemic heart disease -
Core enzymology laboratory (human)
P50HL- 175 70-04 0021 Study of ischemic heart disease -
Enzymatic evaluation of acute myocardial infarction (dogs)
P50HL- 176 82-04 0010 Study of ischemic heart disease ■
Core clinical enzyme laboratory (human, mice, dogs, rats)
P50HL-17582-04 0018 Study of ischemic heart disease -
Biochemistry of ischemia-Heart cell and organ culture
(mice, rats, cattle)
ROlHL-17963-04 Human erythrocyte carbonic anhydrase
ROlHL-17976-18 Chemical agents and heart glycolytic
enzymes (sheep)
R01HL-18557-03 A routine diagnostic test for minimal
heart damage (human, rat)
ROlHL-18723-03 Genetic heterogeneity of acid lipase-
Atherosclerosis (human)
[PI
ROIHI IH908 01 An|iat*n%ifl convwling •n/ynii ol human
%rruin
ROIHI 19062 03 Pharmacologic control of matt ctll
phosphodieilerate (human, rati)
ROIHI 199/4 02 P-.ythulugic behavioral inlluancei on
heart pathology (rats)
POIHI 20557 02 0010 The developm«nl and regression ol
cardiac hypertrophy Fnergy metabolism in the
hypertrophied heart animaK
ROIHI 70658 01 Myocardial energy lr«n%port Creative
kinase (human, cattle, dog)
ROIHI 71678 07
(rabbit)
ROIHL 77742 01
human)
ROIHL 22265 02
Biosynthesis ol lung surfactant lipid
The converting enzyme of lung (cattle.
Isozymes ol heart glutamate aspartate
transaminase (swine, ducks)
ROIHL 22288 01 Renin and precursors Structure and
function (mice)
ROIHL 22664 01 Regulation of myocardial cell growth
(rats, guinea pigs)
ROIHL 22967 01 Structure and function of heparin
releasable lipases (swine, human)
R23HL 22984 01 Cyclic AMP dependent protein kinases in
hypertension (rat)
ENZYMES, METALLOENZYMES
•• ROIHL 11614 11 Trace elements in nutrition (chickens,
rats, human)
ROIHL 1857904 Synthetic protease inhibitors
ROlHL-18905-04 Acquisition of native conformation of
proteins (human, cattle)
ROIHL 19132 04 Role of zinc transferrin in lymphocyte
transformation (human)
" ROIHL 19392-03
metalloproteins
R01HL2139402
(rabbits)
ROlHL-22387-01
Spectroscopic studies of respiratory
Pulmonary angiotensin-converting enzyme
Metalloenzymes and disease
ENZYMES, ZYMOGENS
ROlHL-04366 19 Plasminogen Activation and structure-
function relations (mammals, birds)
P50HL-15062-07 0008 Study of lipoproteins, artery wall,
and atherosclerosis • Lipid modifying enzymes (human,
monkey)
ROlHL-18834-04 Metal-dependent complex formation in
blood coagulation (human, cattle)
ROlHL-20 106-02 Coupling of platelet contractile proteins
to fibrin (human)
ROlHL-21 113-01 Control mechanisms in coagulation
(cattle)
ROlHL-2154302 Structure-function relation of blood
clotting proteins (rabbits)
ROlHL-22505-01 Molecular pathology of fibrinogen and
factor XIII (human, animals)
** ROlHL-22980-01 Kinetic and mechanistic studies of blood
coagulation (human, cattle)
EOSINOPHIL LEUKOCYTES
SEE BLOOD CELLS, LEUKOCYTES, EOSINOPHILS
EPICARDIAL MAPPING
SEE HEART VISUALIZATION, EPICARDIAL MAPPING
EPIDEMIOLOGIC STUDIES REVIEW COMMITTEE
** ROlHL-22472-01 Smoking risk-factor reduction-
Maintenance strategies (human)
EPIDEMIOLOGY, EPIDEMIOLOGIC METHODS
SEE POPULATION STUDIES HUMAN, EPIDEMIOLOGY
EPIDEMIOLOGY AND DISEASE CONTROL STUDY
SECTION
*• ROlHL-03341-22 Epidemiology of atherosclerosis in Evans
Co Georgia
** ROlHL-03429-18 Central nervous system and coronary
heart disease (human)
** ROlHL-12833-09 Genetic and environmental influences on
lung disease (human)
** ROlHL-13974-07 Ventricular premature beats and sudden
coronary death (human)
** R01HL-15174-06 CV disease epidemiology-Second
generation studies (human)
** ROIHL 15191-07 Multiparameter methods for
cardiovascular research
*• ROlHL-15614-04 Heredity and oxygen-Effects on health of
heart-lungs (South America)
** ROlHL-15790-05 Follow-up study of acute coronary heart
attacks (human)
** R01HL-15403-05 Prognostication by computer-Analyzed
vectorcardiogram (human)
** ROlHL-15461-05 Late results of valve replacement-
Computer analysis (human)
** ROlHL-16651-05 Evaluation of steroid therapy in
sarcoidosis (human)
" ROlHL-17580-04
disease (men)
ROlHL-18175-03
community
ROlHL-18235-03
factors (human)
ROlHL-18455-03
adolescents
The impact of stress on coronary heart
Drug taking for hypertension in a rural
Cardiovascular fitness and other risk
Cardiovascular follow-up of hypertensive
(contd)
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
••Oriented significantly to above subject.
M Grant has subprojects deschbing specific research aspects.
See Appendix for investigator's name and grant number.
EPI
ROlHL-18683-03 Left ventricle function in aortic
regurgitation (human)
ROlHL-18715-02 Hypertension incidence project (human)
R01HL18850-03 Classification code for Frank orthogonal
ECG
ROIHL 18907-03 Objective evaluation early after Ml and
heart surgery (human)
ROlHL-19073-02 Heart disease and drinking water at
Prevention of high blood pressure In
Coronary risk factors (human)
Epidemiology of sudden cardiac death
Vascular lesions of diabetes in Oklahoma
Genetic patterns in deaths from Ml and
Community studies of obstructive lung
Prospective study of bundle branch block
Atherosclerotic disease and risk factors
home
" ROlHL-19877-02
children
" ROlHL-2012402
** ROlHL-20179-02
among women
** R01HL-2063702 Recovery after heart surgery-Bio-
behavioral factors (human)
** ROlHL-20662-02 Physical activity, fitness and
epidemiology of CHD
" ROlHL-20724-01 Behavioral consequences of hypertension
(human)
** ROlHL-21039-02
Indians
" ROlHL-21088-02
stroke in Utah
" RaiHL-21352-02
disease (human)
" ROlHL-21527-01
(human)
" ROlHL-21971-01
in twins (human)
** ROlHL-22255-01 The etiology/prevalence of peripheral
arterial disease (human)
** ROlHL-22378 01 Psyco somatic predictors of CHD in
adolescence (human)
** ROlHL-22514 01 Behavior patterns, stress, and
catecholamines
*' ROlHL-22528-02 Early risk predictors for chronic
pulmonary disease (human)
** ROlHL-22547-01 Behavioral treatment of Raynaud's
disease (human)
** ROIHL 22740-01 Behavior and cardiovascular disease -
Basic mechanisms (human)
** ROlHL-22802-01 A rural mining community hypertension
control project (human)
** ROlHL-22809-01 Coronary-prone behavior and
cardiovascular reactivity (human)
" ROlHL-22838-01 Post-transfusion hepatitis in neviborn
children
** R18HL-22934-01 Behavorial approaches to adolescent
hypertension
** ROlHL-22982-01 Multicenter postcoronary risk
stratification program (human)
EPIDEMIOLOGY OF CARDIOVASCULAR
DISORDERS
SEE CARDIOVASCULAR DISORDERS EPIDEMIOLOGY
EPIDEMIOLOGY OF MENTAL DISORDERS
SEE MENTAL HEALTH EPIDEMIOLOGY
EPIDEMIOLOGY OF NEOPLASTIC DISEASE
SEE NEOPLASTIC DISEASE EPIDEMIOLOGY STATISTICS
EPIDEMIOLOGY OF NERVOUS DISORDERS
SEE NERVOUS DISORDERS EPIDEMIOLOGY
EPIDEMIOLOGY OF RESPIRATORY DISORDERS
SEE RESPIRATORY DISORDERS EPIDEMIOLOGY
EPIDERMAL GROWTH FACTOR
SEE GROWTH FACTORS (INCL. ANABOLICS), EPIDERMAL
GROWTH FACTOR
EPIDERMIS
SEE SKIN (GENERAL)
EPIDIDYMIS
SEE REPRODUCTIVE SYSTEM MALE, EPIDIDYMIS AND DUCTS
EPILEPSY
SEE BRAIN DISORDERS, EPILEPSY
EPINEPHRINE
SEE PHENYULKYLAMINES, CATECHOLAMINES, EPINEPHRINE
EPISTAXIS
SEE NASAL DISORDERS. EPISTAXIS
EPITHELIAL MYOCYTES
SEE MUSCLE CELLS, MYOEPITHELIAL CELLS
EPITHELIAL TRANSPORT DISORDERS INBORN
SEE METABOLIC DISORDERS INBORN, TRANSPORT
DISORDERS
EPITHELIUM
SEE TISSUE, EPITHELIUM
EPIZOOTIOLOGY
SEE POPULATION STUDIES ANIMAL, EPIZOOTIOLOGY
■^C^IDES
' OXIDES, EPOXIDES
EPSTEiN-BARR VIRUS
SEE VIRUSES, HERPESVIRUSES, EB VIRUS
206
EQUILIBRIUM SENSE
SEE SENSORY PERCEPTUAL PROCESSES, PROPRIOCEPTION
EQUIPMENT, LABORATORY
SEE BIOMEDICAL FACILITIES
EQUIPMENT FOR ANIMAL CARE
SEE ANIMALS. VETERINARY SCIENCE, ANIMAL CARE
ERGOT ALKALOIDS
SEE ALKALOIDS, ERGOT
ERYTHEMA
SEE SKIN DISORDERS, ERYTHEMA
ERYTHROBLASTIC ANEMIA (MEGALOBLASTIC)
SEE BLOOD AND RE DISORDERS, ANEMIA MEGALOBLASTIC
ERYTHROBLASTOSIS FETALIS ABO NEWBORN
SEE BLOOD GROUP INCOMPATIBILITY PERINATAL, ABO
HEMOLYTIC DISEASE NEWBORN
ERYTHROBLASTS
SEE BLOOD CELLS, ERYTHROBLASTS AND ERYTHROID STEM
CELLS
ERYTHROCEBUS
SEE MAMMALS, PRIMATES, MONKEYS AND APES
(ANTHROPOIDS, NON-HUMAN), OLD WORLD MONKEYS
(CATARRHINES)-
ERYTHROCUPREIN
SEE METALLOPROTEINS, CYTOCUPREINS
ERYTHROCYTE GHOST
SEE MEMBRANE, ERYTHROCYTE GHOST AND MEMBRANE
ERYTHROCYTE MEMBRANE
SEE MEMBRANE, ERYTHROCYTE GHOST AND MEMBRANE
ERYTHROCYTE SEDIMENTATION
SEE BLOOD (HEMATOLOGIC) TESTS, BLOOD SEDIMENTATION,
ERYTHROCYTE*
ERYTHROCYTES
SEE BLOOD CELLS, ERYTHROCYTES
ERYTHROID STEM CELLS
SEE BLOOD CELLS, ERYTHROBLASTS AND ERYTHROID STEM
CELLS
ERYTHROLEUKEMIA
SEE NEOPUSMS OF BLOOD AND RE SYSTEM. LEUKEMIA,
ERYTHROLEUKEMIA
ERYTHROPOIESIS
SEE BLOOD AND RE SYSTEM, HEMATOPOIESIS,
ERYTHROPOIESIS
ERYTHROPOIETIC INHIBITORS
SEE BLOOD AND RE SYSTEM, HEMATOPOIETIC FACTORS,
ERYTHROPOIETIC INHIBITORS
ERYTHROPOIETIC PROTOPORPHYRIA
SEE METABOLIC DISORDERS INBORN, PORPHYRIA,
PROTOPORPHYRIA
ERYTHROPOIETIN
SEE BLOOD AND RE SYSTEM, HEMATOPOIETIC FACTORS.
ERYTHROPOIETIN
ESCAPE REACTION
SEE PSYCHOLOGY, BEHAVIOR, ESCAPE REACTION
ESERINE
SEE BENZOPYRROLES, PHYSOSTIGMINE
ESOPHAGEAL VARICES
SEE GASTROINTESTINAL CIRCULATORY DISORDERS,
ESOPHAGEAL VARICES
ESOPHAGUS
SEE GASTROINTESTINAL SYSTEM, ESOPHAGUS
ESR
SEE CHEMISTRY, ANALYTICAL METHODS, SPECTROMETRY,
ESR*
ESSENTIAL FATTY ACIDS
SEE NUTRITION, DIETARY CONSTITUENTS, DIETARY LIPIDS.
ESSENTIAL FATTY ACIDS
ESTERASES
SEE ALSO ENZYME INHIBITORS, ANTIESTERASES
SEE ALSO PHOSPHODIESTERASES
R01HL-12740-10 Hypocholesterolemic agents-
Stereochemistry (rats)
ROIHL- 158 17-06 Plasminogen activators from tissues
(human, pig, cattle)
ROlHL-18089-04 Fatty acid metabolism in heart and its
regulation (swine, rats)
ROlHL-21008-02
cultures (rats)
ROlHL-21513-02
•Excludes routine methodology OR covers only general projects which preclude indexing
••Oriented significantly to above subject
rats, swine)
ROlHL-23969-01
vitro (rats)
at the specific level.
Effect of pollutants on organotypic lung
Metabolism of trans fatty acids (human.
Surfactant synthesis by type II cells in
Acid and alkaline lipases in aortas (rats.
Lipid deposition in mammalian cells
EST
ESTERASES, CHOLESTEROL ESTERASE
*• ROIHL 02033-23 Regulation of cholesterol esters in blood
and tissues (rat, cattle, human)
POlHL-12373-10 0006 Cardiopulmonary physiology and
pathophysiology - Fatty acid metabolism-Regulation,
implications (human, mammals, birds)
ROlHL-12869-09 Arterial metabolism, diabetes and
atherogcnesis (rats, rabbits)
POlHL-13262-07 0015 Arterial wall in atherosclerosis -
Crosslinkage biosynthesis in aortic elastin and collagen
(animals)
POlHL-13262-07 0025 Arterial wall in atherosclerosis -
Phospholipid and cholesterol esters
ROlHL-13722-08
rabbits, human)
RClHL-14781-08
(mice)
** ROlHL-17371-05 Regualtion of cholesteryl ester levels in
the aorta (swine)
ROlHL-18157-04 Subcellular events in atherosclerosis
(human, rabbits, calves)
ROlHL-18682-03 Protein kinase and cholesterol
metabolism in aorta (rabbits)
ROlHL-20061-02 Serum lipoproteins and cell cholesterol
metabolism (rats, human)
ESTERIFICATION
*♦ POlHL-06835-17 0015 Cardiovascular disease - Plasma
cholesterol esterification in canine atherosclerosis
POlHL-06835-17 0063 Cardiovascular disease - Studies
on prostaglandins (human, rabbits)
ROlHL-09489 13 Myocardial lipid metabolism and
regulation (rats)
ROlHL-13302-09 Uptake and metabolism of lipids by the
liver (rats)
P50HL-14164-07 0035 A/S SCOR-Comparative and
experimental atherosclerosis - Lipid metabolism -Interaction
with arterial metabolism (monkey, pigeon)
ROlHL-14990-07 Lipid transport in avian species
(chickens)
ROlHL-17332-04 Use of the gut for therapy of coronary
artery disease (mammals)
P01HL-22633-01 0002 Cellular and molecular biology of
lipoprotein metabolism - Sterol metabolism in tissue
culture cells
ESTERS
POlHL-08214-15 0005 Chemical and biological properties
of lipids - Metabolism of lipids in animals
** POlHL-15596-05 0012 Coagulation, fibrinolysis.
hemostasis and hepatitis - Platelet function -Phorbol ester
and zymosan-induced release activity
ESTIVATION
SEE ENVIRONMENT, ADAPTATION, ESTIVATION
ESTRADIOL
SEE ESTRATRIENE SERIES, ESTRADIOL
ESTRATRIENE SERIES, ESTRADIOL
ROlHL-10612-13 0021 Humoral factors in heart failure
and hypertension The control of aldosterone secretion
(dogs)
POlHL-16387-04 0002 The blood vessel and
thrombogenesis - Hormonal effects on thrombogenesis
(rats, rabbits)
** ROIHL-19322-03 Role of pituitary hormones in the action
of vitamin K (rats)
ROlHL-22607-01 Role of apolipoprotein E in lipoprotein
metabolism (human)
ESTRATRIENE SERIES, ESTRIOL
ROlHL-10612-13 0021 Humoral factors in heart failure
and hypertension - The control of aldosterone secretion
(dogs)
ESTRATRIENE SERIES, ESTROGENS
SEE ALSO ESTRATRIENE SERIES, ESTRADIOL
SEE ALSO ESTRATRIENE SERIES, ESTRIOL
ROlHL-03941-18 Uterine blood flow and changes in
pregnancy (sheep)
ROlHL-06221-17 Composition and structure of plasma
lipoproteins (human, turkeys, baboons)
POlHL-06835-17 0064 Cardiovascular disease - Studies
in atherosclerosis (human, animals)
ROlHL-08888-12 Cooperative study of drugs and coronary
heart disease (men)
ROlHL-10445-09 Cooperative study of drugs and coronary
heart disease (men)
ROlHL-10705-09 Cooperative study of drugs and coronary
heart disease (men)
ROIHL-11372-08 Cooperative study of drugs and coronary
heart disease (men)
ROlHL-12085-10 Lipoprotein-carbohydrate metabolism
(human, rats)
POlHL-12373-10 0006 Cardiopulmonary physiology and
pathophysiology - Fatty acid metabolism-Regulation,
implications (human, mammals, birds)
ROlHL-12766-09 Structure-function relation of blood
vessels (rats, monkeys)
P01HL-14388-07 0232 Regulation of the circulation in
pathological states - Idiopathic cyclic edema
ROlHL-14526-07 Oral contraceptives and hypertension
(rats)
(contd)
I
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
£S1
ROIHl 14692-06 Alpha I antitiypsin daticiviicy irid
pulmonaiY disaasa (human)
" POIHI M9g:>0/ OOli Ailaplation lo hypoiia Pit|nincy
at hi|h altituda (human, animals)
ROIHL IbSBl 06 Coronary How studws ol partially
obitrucltd vassals (dogs)
ROIHI l!>808 06 Rola ol an|iotensinogen in hypartension
and siroka (human, rabbits)
ROIHI I6!>li!04 lipoprotein metabolism and hormonal
regulation (chickens)
ROIHI 17721 04 Ellect ol sex hormones on vascular
connective tissue (rats)
ROIHL 18002 03 Circulatory shock, trauma and RE system
tunction (rats)
POIHI I8S74 03 0006 Lipoprotein methodology and
biomedical applications lipoprotein lianslormation.
lipolytic enzymes, diet and lipid lowering agents
ROIHL 1861003 Early inleivention ol age related arterial
changes (pigeon)
POIHL 18645 03 0003 Biology ol the artery wall and
atherosclerosis Synthesis ol connective tissue proteins by
smooth muscle cells (human, monkeys)
POIHL 1864503 0007 Biology ol the artery wall and
atherosclerosis lipoprotein metabolism in subhuman
primates
ROIHL 18731 02 RES stimulating materials in
experimental shock (dogs)
ROIHL 19115 02 Hormonal control ol tracheobronchial
cyclic AMP (rats, guinea pigs)
** ROIHL 2064501 Etiology ot myocardial intaction (human)
** ROIHL 2068502 Pituitaryadrenergicovarian vasomotor
interaction (dogs)
ROIHL 2141802 Experimental myocardial iniarction (rats)
** R01H122079 01 Heart receptor sites lor digitalis and
steroid hormones (animals)
** ROlHl-2236701 Estrogen receptors in very low density
lipoproteins (chicken livers)
ROIHI'22812'01 Regulation ot hepatic production of HDL
(rats)
ESTRATRIENE SERIES, MESTRANOL
SEE Also FERTIIITY. ANTIf ERTIIITY DRUGS, MESTRANOl-
NORETHYNODREl
R01HL1255709 Effects of steroids and pregnancy on
arteries and veins (guinea pigs)
R01H114526-07 Oral contraceptives and hypertension
(rats)
** R01H117724-03 Oral contraceptives and hypertension
(rats)
ROlHL-1914403 Contraceptive steroids and experimental
hypertension (rats)
ESTRIOL
SEE ESTRATRIENE SERIES. ESTRIOL
ESTROGENS
SEE ESTRATRIENE SERIES, ESTROGENS
ETHANOL, ETHYL ALCOHOL
SEE AICOHOIS, ETHANOl
ETHANOLAAAINES
SEE AMINO AICOHOIS. ETHANOLAMINES
1,4-ETHANOPIPERIDINES
SEE QUINUCIIDINES
ETHERS
SEE ALSO HAIOETHERS
SEE Also OXIDES. EPOXIDES
ROlHL'19203-03 Surgical approach to congenital heart
diseases (dogs, primates)
Polyether ionophores -Synthesis of X537A
R01HL.2136702
and analogs
ROlHL-2261201
disease
Stabilized prostacyclins to treat vascular
ETHERS, GLYCEROL ETHERS
SEE LIPIDS. GLYCERYL ETHERS
ETHIONINE
SEE SULFUR AMINO ACIDS, ETHIONINE
ETHNIC GROUPS
SEE SOCIAL GROUPS. ETHNIC
ETHOLOGY (ANIMAL BEHAVIOR)
SEE PSYCHOLOGY. BEHAVIOR ANIMAL
ETHRANE
SEE HAIOETHERS. ETHRANE
24BETA-ETHYL CHOLESTEROL
SEE CHOLESTANE SERIES. BETA-SITOSTEROl
ETHYLENEDIAMINE TETRAACETIC ACID
SEE AMINO ACIDS. ETHYIENEDIAMINO ACIDS, EOTA
ETHYLENE GLYCOL
SEE ALCOHOLS. DIOLS. ETHYLENE GLYCOL
ETHYLENE SUCCINIC ACID
SEE DICARBOXYIIC ACIDS. SUCCINIC ACID
ETIDRONATE
SEE PHOSPHATES. ALKYl PHOSPHATES, ETIDRONATE
ETIOCHOLANOLONE
SI I ANDRdSIANE SCRIES b BEIA, ETIOCHOUNOIONE
EUCHROMATIN
SI I (,INI Ill's CIIHOMOSIIMI S
EUKARYOTIC CELLS (ORGANISMS)
SEE CEllS (ORGANISMS), EUKARY01IC (SEE ALSO
SPECIFICS)
EUMYCOPHYTA
SFf FUNGI*
EVALUATION
SEE COMPUTER. Oi SIGN AND EVALUATION OF COMPUTERS
(INCL HARDWARE)
SEE HOSPIIALS ANAIYSIS
SEE INFOHMAIION AND COMMUNICAIION. SYSTEMS ANALYSIS
SEE IHERAPY tVAlUAIION
EVALUATION AND ANALYSIS OF SYSTEMS
(GENERAL)
SEE INFORMAIION AND COMMUNICATION. SYSTEMS ANALYSIS
EVALUATION OF BIOMEDICAL RESEARCH
PROGRAMS
SEE HEALTH SCIENCES RESEARCH ANALYSIS-EVALUATION-
PUNNING
EVALUATION OF DIAGNOSTIC QUAUTY-
STANDARDS
SEE DIAGNOSTIC QUALITY STANDARDS
EVALUATION (SCREENING) OF DRUGS
SEE DRUGS SCREENING
EVALUATION OF EDUCATIONAL PROGRAMS
(SYSTEMS)
SEE EDUCATION PROGRAMS (SYSTEMS) EVALUATION-
PUNNING
EVALUATION OF HEALTH CARE QUALITY
SEE HEALTH CARE QUALITY
EVALUATION OF HEALTH PERSONNEL
PERFORMANCE
SEE HEALTH SCIENCES PROFESSIONS. HEALTH PERSONNEL
PERFORMANCE
EVALUATION OF HEALTH SERVICES AND
RESOURCES
SEE HEALTH CARE (SERVICESXRESOURCES) ANALYSIS AND
EVALUATION
EVALUATION OF INFORMATION GATHERING
METHODS (GENERAL)
SEE INFORMATION GATHERING METHODS EVALUATION-
STANDARDS
EVALUATION OF INSTRUMENTATION,
CLINICALLY ORIENTED
SEE BIOMEDICAL ENGINEERING. INSTRUMENTATION
ClINICAllY ORIENTED
EVALUATION OF INSTRUMENTATION, NOT
CLINICALLY ORIENTED
SEE BIOMEDICAL ENGINEERING. INSTRUMENTATION NOT
CLINICALLY ORIENTED
EVOKED POTENTIALS
SEE ELECTROPOTENTIAIS, EVOKED POTENTIALS
EVOLUTION
SEE BIOLOGY. SYSTEMATIC. EVOLUTION AND PHYLOGENY
EVOLUTION BIOCHEMICAL
SEE BIOLOGY. SYSTEMATIC. EVOLUTION BIOCHEMICAL
EXCHANGE DIFFUSION
SEE BIOLOGICAL TRANSPORT, PASSIVE TRANSPORT.
DIFFUSION
EXCHANGE TRANSFUSION
SEE BLOOD TRANSFUSION. EXCHANGE
EXCIPIENTS
SEE DRUGS VEHICLES
EXCRETION
SEE BIOLOGICAL TRANSPORT. SECRETORY MECHANISMS.
EXCRETION
EXERCISE
SEE HEALTH, PHYSICAL ACTIVITY. EXERCISE
EXERCISE ELECTROCARDIOGRAPHY
SEE CARDIOVASCUUR DISORDERS DIAGNOSIS. EXERCISE
STRESS TEStiNG*
EXERCISE STRESS TESTING
SEE CARDIOVASCUUR DISORDERS DIAGNOSIS. EXERCISE
STRESS TESTING*
EXERTION
SEE HEALTH. PHYSICAL ACTIVITY. EXERCISE
EXOCYTOSIS
SEE BIOLOGICAL TRANSPORT. ACTIVE TRANSPORT.
PINOCYTOSIS
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject
M Grant has subprotects describing specific research aspects.
See Appendix for investigator's name and grant number.
kit
EXOENZVMES
Ml IN/VMiS. EXnCN/YMFS
EXOTOXINS
SI I IMMIINIMOCY. ANTIGENS BACIERWI. EXOTOXIN:,
EXPECTANCY
SEE PSYCHOIOCY. COGNIIION, EXPECTANCY
EXPECTORANTS
SEE RISHIRAIORY DRUGS. EXPECIOHANTS AND MUCOLYTICS
EXPERIMENTAL PSYCHOLOGY STUDY SECTION
•* ROIHI 1/706 04 Psychosocial hyperten-.ion.
catecholamines and drugs (mice)
" ROIHL 17958 04 Circulatory effects of operant
cardiovascular control (baboons)
** ROIHL 18814 03 Behavio'f' ■ !■ \ lor clinical carjiac
control (huma'
blood pressure du . ..
** ROIHL 18976 03 Blood pressure control Relation to
behavioral stress (liuman (' ';)
** ROIHL 1956803 Hypertension Analysis of drug and
behavioral therapies (human)
** ROIHL 1968001 Cardiac correlates of behavioral stress in
animals (dog)
*• ROIHL 19974-02 Psychdogic-behavioral influences o'.
heart pathology (rats)
** ROIHI 20861 01 Card -spiralory renal stress rea. ions
(dogs)
EXPERIMENTAL VIROLOGY STUDY SECTION
** ROIHL 19163 02 Piscine erythrocytic necrosis in the
Atlantic cod
" ROIHL 1915403 Piscine erythrocytic necrosis in the
Atlantic cod
** ROIHL 19381-03 Pathogenesis of viral induced
atherosclerosis (human, chicken)
*' ROIHL 21047-01 Studies of coxsackievirus induced
myocarditis in mice
** ROlHL-2358801 NOV infection- Analysis at the subcellular
level (chickens)
EXTINCTION (PSYCHOLOGY)
SEE PSYCHOLOGY. CONDITIONING, EXTINCTION
EXTRACELLULAR ENZYMES
SEE ENZYMES. EXOENZYMES
EXTRACELLULAR SPACE
SEE BODY FLUIDS. EXTRACELLUUR SPACE (COMPARTMENT)
EXTRACORPOREAL CIRCULATION
SEE CARDIOVASCUUR SURGERY, EXTRACORPOREAL
CIRCUUTION
EXTRACORPOREAL DIALYSIS
SEE BLOOD TREATMENT. HEMODIALYSIS
EXTRATERRESTRIAL, SUPRATERRESTRIAL
ENVIRONMENT
SEE ENVIRONMENT. EXTRATERRESTRIAL. SUPRATERRESTRIAL
EXTREMITIES
SEE SKELETAL SYSTEM. LIMB
EXTRINSIC FACTOR
SEE VITAMIN B12
EXTRINSIC SURFACE ACTIVITY OF MEMBRANES
SEE MEMBRANE SURFACE (BIOLOGICAL) ACTIVITY (GENERAL)
EXUDATES AND TRANSUDATES
SEE BODY FLUIDS. EXUDATES AND TRANSUDATES
EYE, AQUEOUS HUMOR
POlHL-08899-14 0003 Tolerance to respiratory gases in
health and disease Inert gas exchange in the eye
(human, dogs)
EYE, CONJUNCTIVA
ROlHL-22118-02 Microcirculation in patients with diabetes
mellitus
EYE, CORNEA
** POlHL-22602-01 0003 Pathophysiology of the
endothelium - Mechanisms of endothelial proliferation
(human, animals)
EYE, LENS
POlHL-08899-14 0003
health and disease
(human, dogs)
EYE, PHOTORECEPTORS
POlHL-14388-07 9003 Regulation of the circulation in
pathological states - Electron probe projects
EYE, RETINA
** P01HL06664-17 0036 Cardiopulmonary function in
remediable vascular disease - In vitro studies on the
mechanism of ischemic damage to cells (rabbits)
POlHL-08899-14 0007 Tolerance to respiratory gases in
health and disease Effects of high oxygen pressures on
visual function (human, animals)
(CDIltd)
Tolerance to respiratory gases in
Inert gas exchange in the eye
EYE
208
FAM
POlHL-08899-14 0049 Tolerance to respiratory gases in
health and disease - Dose-response measures of severe
oxygen toxicity (monkeys)
** POlHL-0889914 0051 Tolerance to respiratory gases in
health and disease - Oxygen effects upon isolated retinal
metabolism (rabbits, monkeys)
POlHL-14388-07 9003 Regulation of the circulation in
pathological states - Electron probe projects
EYE, TRABECULARMESHWORK
P60HL15168-070005 Comprehensive sickle cell disease
center - Ophthalmology (human, rabbits, monkeys)
EYE.VISION
SEE ALSO BRAIN. VISUAL PATHWAYS
P01HL08899-14 0047 Tolerance to respiratory gases in
health and disease Oxygen effects on visual function
(human)
** P01HL0889914 0048 Tolerance to respiratory gases in
health and disease - Changes in human vision during
known tolerable exposures
EYE, VISION, COLOR VISION
POlHL-08899-14 0048 Tolerance to respiratory gases in
health and disease - Changes in human vision during
known tolerable exposures
EYE, VISION, DARK ADAPTATION
POlHL-08899-14 0048 Tolerance to respiratory gases in
health and disease - Changes in human vision during
known tolerable exposures
EYE, VISUAL FIELDS
** POlHL-0889914 0007 Tolerance to respiratory gases in
health and disease - Effects of high oxygen pressures on
visual function (human, animals)
POlHL-0889914 0047 Tolerance to respiratory gases in
health and disease - Oxygen effects on visual function
(human)
POlHL-08899-14 0048 Tolerance to respiratory gases in
health and disease - Changes in human vision during
known tolerable exposures
POlHL-08899-14 0067 Tolerance to respiratory gases in
health and disease Inert gas influences upon visual
function in man
EYE, VISUAL PERCEPTION
POlHL-07896-15 0019 Environmental biomedical research
program - Hyperoxic myopia (human)
POlHL-08899-14 0007 Tolerance to respiratory gases in
health and disease - Effects of high oxygen pressures on
visual function (human, animals)
EYE, VISUAL PIGMENTS
POlHL-08899-14 0047 Tolerance to respiratory gases in
health and disease - Oxygen effects on visual function
(human)
POlHL-0889914 0049 Tolerance to respiratory gases in
health and disease - Dose-response measures of severe
oxygen toxicity (monkeys)
** POlHL-08899-14 0050 Tolerance to respiratory gases in
health and disease • Effects of high oxygen pressures on
visual pigment functions (monkeys)
EYE, VISUAL STIMULUS
P50HL-14214-07 0032 Newborn lung center for hyaline
membrane disease - Evoked electroencephalographic
potential in infants with HMD (human)
EYE, VITREOUS BODY
POlHL-0889914 0003 Tolerance to respiratory gases in
health and disease • Inert gas exchange in the eye
(human, dogs)
EYE CIRCULATION
ROlHL-221 18-02 Microcirculation in patients with diabetes
mellitus
EYE CIRCULATION, OPHTHAUMIC ARTERY
R01HL1903802 Plethysmographic evaluation of carotid
blood flow (human, rabbits, dogs)
EYE CIRCULATION, RETINAL ARTERIES
POlHL-0789615 0019 Environmental biomedical research
program • Hyperoxic myopia (human)
EYE CIRCULATION, RETINAL-CHOROIDAL
CIRCULATION
** POlHL-0789615 0051 Environmental biomedical research
program - Relationships of retinal circulation to disease
(rabbits)
ROlHL-23603-01 Morphogenesis of hypertensive vascular
disease (rats)
EYE CIRCULATORY DISORDERS
SEE ALSO EYE DISORDERS, RETROLENTAL FIBROPLASIA
** P60HL-15168-07 0005 Comprehensive sickle cell disease
center - Ophthalmology (human, rabbits, monkeys)
EYE CIRCULATORY DISORDERS, RETINAL
CIRCULATORY DISORDERS
SEE ALSO CARBOHYDRATES METABOLISM DISORDERS,
DIABETIC RETINOPATHY
•* POlHL-07896-15 0051 Environmental biomedical research
program - Relationships of retinal circulation to disease
(rabbits)
P50HL-14217-08 0063 Specialized center of research In
thrombosis - Special clinical studies laboratory
P50HL-14230-07 0097 A/S SCOR -Lipids, atherosclerosis
and thrombosis - Studies of circulating platelet aggregates
(human)
P60HL15ie8-07 0005 Comprehensive sickle cell disease
center - Ophthalmology (human, rabbits, monkeys)
EYE CIRCULATORY DISORDERS, RETINAL
(INCLUDING VITREOUS) HEMORRHAGE
ROlHL-14102-07 Human physiology at 5360 meters -
Mountain environment
P60HL-151 68-07 0005 Comprehensive sickle cell disease
center - Ophthalmology (human, rabbits, monkeys)
** POlHL-2 10 16-02 0016 Sickle cell anemia and other
hemoglobinopathies - The treatment of sickle cell
retinopathy (human)
ROlHL-211 17-01 Altitude adaptation in chronic lung
disease (human)
EYE DISORDERS
SEE ALSO CARBOHYDRATES METABOLISM DISORDERS,
DIABETIC RETINOPATHY
POlHL-08899-14 0003 Tolerance to respiratory gases in
health and disease - Inert gas exchange in the eye
(human, dogs)
P60HL 15158-07 0011 Comprehensive sickle cell center -
Clinical services-Adult patients
" P60HL-1516807 0005 Comprehensive sickle cell disease
center - Ophthalmology (human, rabbits, monkeys)
EYE DISORDERS, GLAUCOMA
ROlHL-1983909 Factors in youth predisposing to chronic
diseases (former college students)
ROlHL-22258-01 New aspects of pharmacology related to
carbonic anhydrase
EYE DISORDERS, LENS DISORDERS, CATARACT
R01HL1983909 Factors in youth predisposing to chronic
diseases (former college students)
EYE DISORDERS, PAPILLEDEMA
ROlHL-21 117-01 Altitude adaptation in chronic lung
disease (human)
EYE DISORDERS, RETINA AND CHOROID
DISORDERS (GENERAL)
SEE ALSO CARBOHYDRATES METABOLISM DISORDERS,
DIABETIC RETINOPATHY
P60HL-I5168-07 0002 Comprehensive sickle cell disease
center ■ Patient care
" P60HL-15168-07 0005 Comprehensive sickle cell disease
center - Ophthalmology (human, rabbits, monkeys)
EYE DISORDERS, RETINA AND CHOROID
DISORDERS, RETINA DETACHMENT
P60HL-15168-07 0005 Comprehensive sickle cell disease
center - Ophthalmology (human, rabbits, monkeys)
POlHL-21016-02 0016 Sickle cell anemia and other
hemoglobinopathies - The treatment of sickle cell
retinopathy (human)
EYE DISORDERS, RETROLENTAL FIBROPLASIA
** POlHL-08899-14 0047 Tolerance to respiratory gases in
health and disease - Oxygen effects on visual function
(human)
EYE DISORDERS CHEMOTHERAPY
ROlHL-22258-01 New aspects of pharmacology related to
carbonic anhydrase
EYE DISORDERS DIAGNOSIS (INCL EXAMS)*
POlHL-07896-15 0019 Environmental biomedical research
program - Hyperoxic myopia (human)
EYE DISORDERS DIAGNOSIS, PUPIUOGRAPHY*
P01HL08899-14 0051 Tolerance to respiratory gases in
health and disease - Oxygen effects upon isolated retinal
metabolism (rabbits, monkeys)
EYE DISORDERS DIAGNOSIS, RETINOGRAPHY*
** ROlHL-14148-07 0004 The regional circulations -
Funduscopic mapping by photography (human)
EYE DISORDERS DIAGNOSIS, RETINOGRAPHY,
ELECTRO RETINOGRAPHY*
POlHL-08899-14 0007 Tolerance to respiratory gases in
health and disease - Effects of high oxygen pressures on
visual function (human, animals)
POlHL-08899-14 0048 Tolerance to respiratory gases in
health and disease - Changes in human vision during
known tolerable exposures
P01HL08899-14 0049 Tolerance to respiratory gases in
health and disease - Dose-response measures of severe
oxygen toxicity (monkeys)
POlHL-0889914 0051 Tolerance to respiratory gases in
health and disease - Oxygen effects upon isolated retinal
metabolism (rabbits, monkeys)
EYE EXAMINATIONS
SEE EYE DISORDERS DIAGNOSIS (INCL E)(AMS)*
EYE INJURIES
SEE INJURIES, EYE
EYE REFRACTIVE DISORDERS, MYOPIA
" POlHL-07896-15 0019 Environmental biomedical research
program - Hyperoxic myopia (human)
EYE SURGERY
** P60HL-15168-07 0005 Comprehensive sickle cell disease
center - Ophthalmology (human, rabbits, monkeys)
POlHL-2101602 0016 Sickle cell anemia and other
hemoglobinopathies - The treatment of sickle cell
retinopathy (human)
EYE SURGERY, VITRECTOMY
P60HL-1516807 0005 Comprehensive sickle cell disease
center - Ophthalmology (human, rabbits, monkeys)
FACILITATED DIFFUSION
SEE BIOLOGICAL TRANSPORT. PASSIVE TRANSPORT,
DIFFUSION
FACILITIES
SEE ANIMAL FACILITIES, RESOURCES
SEE BIOMEDICAL ENGINEERING. INSTRUMENTATION CENTERS
SEE BIOMEDICAL FACILITIES
SEE BIOMEDICAL SYSTEMS AUTOMATED
SEE COMPUTER CENTERS
SEE HEALTH CARE FACILITIES (GENERAL)
SEE STATISTICAL SERVICE AND CENTERS
FACTOR I DEFICIENCY
SEE BLOOD COAGULATION DISORDERS. AFIBRINOGENEMIA
FACTOR II
SEE BLOOD COAGULATION. PROTHROMBIN
FACTOR II DEFICIENCY
SEE BLOOD COAGUUTION DISORDERS.
HYPOPROTHROMBINEMIAS
FACTOR III
SEE BLOOD COAGULATION, THROMBOPUSTIN
FACTOR V
SEE BLOOD COAGULATION, FACTOR V
FACTOR VI
SEE BLOOD COAGUUTION. FACTOR V
FACTOR VII
SEE BLOOD COAGUUTION, FACTOR VII
FACTOR VII DEFICIENCY
SEE BLOOD COAGUUTION DISORDERS, FACTOR VII
DEFICIENCY
FACTOR VIII
SEE BLOOD COAGUUTION, FACTOR VIII
FACTOR VIM DEFICIENCY
SEE BLOOD COAGUUTION DISORDERS, HEMOPHILIA
FACTOR IX
SEE BLOOD COAGUUTION, FACTOR IX
FACTOR IX DEFICIENCY
SEE BLOOD COAGUUTION DISORDERS, CHRISTMAS DISEASE
FACTOR X
SEE BLOOD COAGUUTION. FACTOR X
FACTOR XI
SEE BLOOD COAGUUTION. FACTOR XI
FACTOR XI DEFICIENCY
SEE BLOOD COAGUUTION DISORDERS. FACTOR XI
DEFICIENCY
FACTOR XII
SEE BLOOD COAGUUTION, HAGEMAN FACTOR
FACTOR XIII
SEE BLOOD COAGUUTION. FIBRIN STABILIZING FACTOR
FAD
SEE FUVIN NUCLEOTIDES, RIBOFUVIN NUCLEOTIDES. FAD
FAILURE TO THRIVE INTRAUTERINE
SEE PREGNANCY DISORDERS, EMBRYO-FETAL GROWTH-
DEVELOPMENT DISORDERS (SEE ALSO APPROPRIATE
SPECIFICS)
FAILURE TO THRIVE POSTNATAL
SEE GROWTH DISORDERS POSTNATAL (SEE ALSO
APPROPRIATE SPECIFICS)
FAINTING
SEE NEUROLOGIC MANIFESTATIONS. SYNCOPE
FAMILIAL DISORDERS
SEE GENETIC DISORDERS (SEE ALSO APPROPRIATE
CONGENITAL ABNORMALITIES)
FAMILIAL DISORDERS, METABOLIC ERRORS
SEE METABOLIC DISORDERS INBORN
FAMILIAL DYSAUTONOMIA
SEE CONGENITAL ABNORMALITIES, NEUROLOGICAL.
DYSAUTONOMIA FAMILIAL
FAMILY
SEE ALSO CHILDREN
'Excludes routine methodok>gy OR cavers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
rAM
P6(Wl'IMSI 0/ 0009 Compt(htnsiv« sickle cell center
Counjtiini ind social seivices
P«OHL l!>l69 0b OOU Support lot cenlei lor sickle cell
disease Study ol the neluiil history of sickle cell disease
lr\ the home
** R2bHL 1841403 Hypertension Family strategies lor
patient adherence
ROIHL 19877 02 Prevention ol high blood pressure in
children
ROIHL 20910 02 The alternative diet lor coionary disease
prevention (human)
ROIHL 22021 01 Asthma in lamilies Behavior analysis ol
tamihl interaction pattern
" NOIHR 72973 01 Health education and attitudes ol lamily
toward asthmatic children
NOIHR 72974 01 Sell management systems lor asthmatic
children
FAMILY, CHILD REARING
ROIHL 1992903 High blood pressure in the young,
prevalence and precursors (human)
FAMILY, AAARRIAGE
ROIHL 20179 02 Epidemiology ol sudden cardiac death
among women
FAMILY, MATERNAL BEHAVIOR
" ROIHL 19929 03 High blood pressure in the young,
prevalence and precursors (human)
FAMILY, PARENT-OFFSPRING
P50HL 14141 05 0001 SCOR lor atherosclerosis m
childhood Clinical implications (infants and children)
ROIHL 2202101 Asthma in families-- Behavior analysis of
family interaction pattern
FAMILY, PARENTS
R23HL21150 02 Regulation of airway mucous glands and
ion transport (dogs, ascaris)
FAMILY, TWINS AND MULTIPLETS
ROlHL-03429-18 Central nervous system and coronary
heart disease (human)
P50HLI4159-08 0021 Specialized center of research in
hypertension - Genetic studies of the physiology of
hypertension (human, rats)
R01HL15659-05 Dynamic isolation studies of control of
respiration (human)
" ROIHL 19930-03 A prospective study-Blood pressure in
newborn twins
ROlHL-20034-03 Hypertension-Psychophysiologic and
genetic precursors (human)
ROlHL-21 156-02 Antitrypsin and other causes of chronic
lung disease
** ROlHL-21971-01 Atherosclerotic disease and risk factors
in twins (human)
** NO lHV-530 10-03 NAS-NRC twin registry
NOlHV-72917-00 Plasma lipoproteins in identical twins
FAMILY MEDICINE
SEE HEALTH CARE SERVICES, PATIENT CARE MANAGEMENT,
COMPREHENSIVE CARE, FAMILY MEDICINE
FAMILY PLANNING
SEE ALSO FERTILITY
SEE ALSO FERTILITY. ANTIFERTILITY DRUGS
SEE ALSO GENETIC DISORDERS, GENETIC COUNSELING
SEE ALSO POPUUTION STUDIES HUMAN
SEE ALSO PREGNANCY
P60HL-15160-07 0003 Center for sickle cell disease -
Genetic counseling in hemoglobinopathies-Dimensions,
effectiveness
P60HL-15170-05 0030 Support for center for sickle cell
anemia - Adult services-Counseling program
FAMILY THERAPY
SEE PSYCHOTHERAPY, FAMILY THERAPY
FARMERS
SEE OCCUPATIONS. AGRICULTURAL WORKERS
FARMER'S LUNG
SEE RESPIRATORY DISORDERS. PNEUMONITIS ALLERGIC
INTERSTITIAL, FARMER'S LUNG
FARNESYL COMPOUNDS
SEE TERPENES, FARNESYL COMPOUNDS
FAST REACTIONS (CHEMISTRY)
SEE CHEMICAL REACTION RATES, FAST REACTIONS
FASTING
SEE NUTRITION. DIET. FASTING
FAT CELLS
SEE CONNECTIVE TISSUE. ADIPOSE, FAT CELLS
FAT EMBOLISM
SEE CARDIOVASCULAR DISORDERS. EMBOLISM, FAT
FAT INDUCED HYPERLIPEMIA FAMIUAL
SEE MCTABOLIC DISORDERS INBORN,
HYPERLIPOPROTEINEMIAS FAMILIAL, TYPE I
FAT MOBILIZING FACTOR, PITUITARY
SEE LIPID MOBILIZING FACTORS PfTUITARY
209
FAT TRANSPORT
S[( IIPIDS TRANSPORT
FATIGUE
SEE HEALTH. PHYSICAL ACIIVIIY. lAIICUl
FATS
SEE LIPIDS, fAIS
FATTY ACID BINDING PROTEIN (Z PROTEIN)
SEE PROIEINS, I PROIIIN
FATTY ACID SYNTHETASE ACTIVITY
SEE LICASES, FAUY ACID SYNIHEIASE COMPLEX
FATTY ACIDS
SEE ALSO NUTRIIION. DIETARY CONSTITUENTS, DIETARY
LIPIDS, ESSENTIAL FATTY ACIDS
NOIHI 32926 10 Analysis ol lipoproteins (animals)
ROIHL 02751 21 Function and metabolism ol serum
albumin (mammals, lish, amphibians)
*• P01HL06835 17 0018 Cardiovascular disease Fatty
acid concentration (rats)
** P01HL06835 17 0019 Cardiovascular disease Fatty
acid distribution (rats)
POIHL 08214 15 0005 Chemical and biological properties
of lipids Metabolism of lipids in animals
POIHL 082 14 15 0006 Chemical and biological properties
of lipids Analysis and properties of lipids
** POIHL 082 14-15 0030 Chemical and biological properties
of lipids - Fatty acid biosynthesis in plant cell cultures and
in plants
P01HL-082U 15 0040 Chemical and biological properties
of lipids - Nuclear magnetic resonance studies of lipids
R0IHL-093e4 14 Ion transport by heart mitochondria
(cattle, rat, rabbit)
ROIHLI 16 14-11 Trace elements in nutrition (chickens,
rats, human)
ROIHL 1361909 Microsomal electron transport in liver
and heart (human, mammals)
ROlHL-13722-08
rabbits, human)
ROlHL-14461-08
(rats)
Lipid deposition in mammalian cells
Acid and alkaline lipases in aortas (rats.
Cardiac metabolism in heart failure
R01HL14781 08
(mice)
ROlHL-15273-06
(human, rats)
ROlHL-15681-06
Metabolism of pulmonary surfactant
Coronary flow studies of partially
obstructed vessels (dogs)
R01HL-16553-0S Diagnosis of myocardial infarction by
radioisotopes (mice, rats, goats)
ROlHL-17371-05 Regualticn of cholesteryl ester levels in
the aorta (swine)
** ROlHL-17523-05 Initial events in thrombus formation on
surfaces (human, rats)
POlHL-17871-04 0010 Kidney, sodium, cardiac output,
arterioles and hypertension - Renal prostaglandins
metabolism in hypertension (rats, dogs)
ROlHL-18607-03 Metabolic and drug studies on
experimental fat embolism (mice)
ROlHL-18746-02 Chemical studies on proteolipid
apoproteins (cattle)
ROlHL-19056-03 Blood triglycerides and lipoprotein lipase
in the lung (rats)
ROlHL-19127-03 Synthesis of molecules for myocardial
imaging (rats)
ROlHL-20787-02 Thromboxanes and prostaglandins -
Biochemical pharmacology (rabbits, human)
R23HL-21393-01 Cardiac adaptation to aging and stress
(rats)
ROlHL-21460-02 Lipoproteins, hemostasis and
atherosclerosis (human, rabbits)
** ROlHL-21513-02 Metabolism of trans fatty acids (human,
rats, swine)
R23HL-21842-01 Control of sugar entry in normal and
diabetic heart (rats)
R23HL-220 11-01 Adrenergic receptor cyclase system in
sensitized lung (rats, guinea pigs)
ROlHL-222 19-01 Prostacyclin and peroxides in blood and
membrane disease
POlHL-22633-01 0003 Cellular and molecular biology of
lipoprotein metabolism - Sterol metabolism in platelets and
megakaryocytes (human, rabbits, guinea pigs)
ROlHL-22739-01 Evolution and progression of pediatric
atherosclerosis
ROlHL-228 13-01 Palmitylcarnitine inhibition of ion pumps
in ischemia (dogs)
FATTY ACIDS, ACETATES
SEE ALSO DICARBOXYLIC ACIDS, OXALACETATE
SEE ALSO FATTY ACIDS, ACETOACETATES
SEE ALSO FATTY ACIDS, GLYCOLATES
ROIHL-14730-07 Fatty acid beta-oxidation in normal and
ischemic hearts (rabbits)
ROlHL-17403-03 Metabolic control of cardiac output
(dogs)
ROlHL-18554-03 Taurine metabolism in mammalian heart
(rodents, cattle, swine)
ROlHL-21209-02 Alterations of metabolism in ischemic
myocardium (swine)
FAT
FATTY ACIDS, ACETOACETATES
ROIHI 21209 02 Allexliont of m«tiboli>m in itchemic
myocardium (iwine)
FATTY ACIDS, ARACHIDONIC ACID
ROIHI Q'/?tt'/ /} Mechanism-, rirgulaling plasma proleint
and solutes (human, dogi)
POIHl 06835 I / 0016 Cardiovascular dlM«M Mdabolic
interactions lo polyunsaturated fatty acidt in ath(ro|tnic
diel (dogs)
ROIHL 1282/08 Regulation ol sodium excretion (do|i,
rats)
POIHI 13262 0/ 0022 Arterial wall in athiroulsroiii
Mechanisms ol platelet prostaglanoin formation
ROIHL 13715 08 Myocardial adenyl cyclase (rats)
P50HL 1414/ 08 0001 Specialised center ol research in
thrombosis Role ol aspirin, other anii platelet agents in
platelet tunction (rat. human)
P50HL 14147 08 0012 Specialized center ol research m
thrombosis Tissue culture study ol arterial cells (human.
hamster)
P50HL 14214 07 0026 Newborn lung center lor hyaline
membrane disease Hemodynamic studies of HMD
Prostaglandins production and blockers (lambs)
ROIHL 14397 07 Hypertension Angiotensin and
prostaglandin pharmacology (animals)
ROIHL 1489007 Platelet prostaglandins (human, rabbits)
ROIHL 1521506 Role ol complement in intravascular
coagulation (rabbits, mice)
ROIHL 1648904 Renal prostaglandins-Synthesis and
lunction (human, dogs, rats)
ROIHL 16634 13 Regulation of metabolism in fibroblasts
and platelets (human, rabbits, sheep)
ROIHL 17516 04 Role of androgen as a risk factor in
atherogenesis (human, animals)
P50HL 17682 04 0021 Study of ischemic heart disease
Prostaglandin biosynthesis in blood vessels from ischemic
myocardium (rat, sheep)
ROIHL 1858603 Role of platelet lipids in hemostasis and
thrombosis (human)
R01HL1871804
reactivity (dogs)
ROIHL- 19806-03
Prostaglandin precursors and vascular
Chemotactic control of airway phagocytes
(human, rabbits)
ROlHL-19997-02 Prostaglandin precursors and intestinal
vasculature (cats, rabbits)
ROlHL-20787-02 Thromboxanes and prostaglandins
Biochemical pharmacology (rabbits, human)
ROlHL-21239-02 Isolation and mechanism of action of
thromboxane A2 (human, rabbits)
R23HL-21490-02
membranes
ROlHL-21874-01
R23HL-22075-01
Studies of enzymes in human platelet
'Excludes loutlne methodok)gy OR cavers only general pmiects which preclude Indexing
••Oriented significantly to aliove subject.
at the specific level.
M Grant has subpmjects describing specific research aspects.
See Appendix for investigator's name and grant number.
SRS-A-lts biosynthesis and action
Metabolism of arachidonic acid in blood
vessels (chickens, mammals)
** ROlHL-22527-01 Prostacyclin-thromboxanes in the
cardiovascular system (human, rabbits)
ROlHL-22563-02 Prostaglandins, the kidney and
hypertension (rats)
ROlHL-22946-01 Prostaglandins, platelet aggregation and
vasoactivity (human, rats, rabbits)
ROlHL-22951-01 Studies on the affect of vitamin E on
platelets (human, rats)
FATTY ACIDS, BUTYRIC ACID
SEE ALSO FATTY ACIDS, BETA-HYDROXYBUTYRIC ACID
ROlHL-19324-02 Mechanisms of the inhibition of sickling
by DBA (human)
FATTY ACIDS, FREE FATTY ACIDS
R01HL12085-10 Lipoprotein-carbohydrate metabolism
(human, rats)
ROlHL-13302-09 Uptake and metabolism of lipids by the
liver (rats)
ROlHL-15797-05 Lipid metabolism and atherosclerosis in
primates (monkeys, human, squirrels)
P50HL-17667-04 0040 Study of ischemic heart disease -
Core biochemistry-Cardiac metabolism (human)
P50HL-18318-03 0015 Pathogenesis and complications of
hypertension - Cultured smooth muscle cells and
microvessel metabolism (mammals)
** ROlHL-18887-03 Hypolipidemic drugs-Effects on FFA-
albumin association (human, cattle)
R01HL-20313-02 Surface-induced thrombosis-Modification
of albumin variants (human, goat)
R01HL-20401-03 Relationship of insulin to catechol
cardiomyopathy (rabbit, pig)
ROlHL-2 1764-01 Ultra microanalysis of prostaglandins and
related compounds (rats)
" ROlHL-22053-02 The disordered lipid metabolism of
diabetes mellitus (chickens, mammals, human)
ROlHL-22101-02 Hormone-substrate interaction in diabetic
myocyte (dogs, rats)
POlHL-22633-01 0001 Cellular and molecular biology of
lipoprotein metabolism - Secretion of lipoproteins by the
perfused liver (rats, rabbits)
ROlHL-22812-01 Regulation of hepatic production of HDL
(rats)
ROlHL-23142-01 Mechanisms of membrane in)ury in
myocardial ischemia (dog)
ROlHL-23 166-01 Pathology of mitochondria in ischemic
myocardium (rats, cattle)
(contd)
FAT
210
FAT
R01HL-23ei8-01 Substrate metabolism in isolated
myocytes in shock (dogs, rats, guinea pigs)
ROIHL'23945-Oe Pathologic eflects on cells of modified
lipoproteins (rats, human)
FATTY ACIDS, GLYCOLATES
ROlHL-16647-05 Studies on the control of sickle cell crisis
(human)
R01HL'23618-01 Substrate metabolism in isolated
myocytes in shock (dogs, rats, guinea pigs)
FATTY ACIDS, BETA-HYDROXYBUTYRIC ACID
SEE ALSO OXIOOREDUCTASES, BETAHYDROXYBUTYRATE
DEHYDROGENASE
ROlHL-21209-02 Alterations of metabolism in ischemic
myocardium (swine)
FATTY ACIDS, 1 0-HYDROXYDECANOIC ACID
ROlHL-02477-23 Biosynthesis and function of lipids
(microorganisms, rats)
FATTY ACIDS, HYDROXY FATTY ACIDS
SEE ALSO DICARBOXYLIC ACIDS, MALIC AGIO
SEE ALSO FATTY ACIDS, GLYCOLATES
SEE ALSO FATTY ACIDS, BETA-HYDROXYBUTYRIC ACID
SEE ALSO FATTY ACIDS, 10-HYDROXYDECANOIC ACID
SEE ALSO FATTY ACIDS, UCTATES
SEE ALSO FATTY ACIDS, MEVALONIC ACID
SEE ALSO TRICARBOXYLIC ACIDS, CITRATES
•* R01HL14730-07 Fatty acid beta-oxidation in normal and
ischemic hearts (rabbits)
FATTY ACIDS, LACTATES
SEE ALSO OXIOOREDUCTASES, LACTATE DEHYDROGENASE
SEE ALSO OXIOOREDUCTASES, D-LACTATE DEHYDROGENASE
" ROlHL-00082-30 Transmembrane movements (barnacles,
frogs, rats)
POlHL-08899-14 0012 Tolerance to respiratory gases in
health and disease - High oxygen for normal brain
metabolism and circulation in man
ROlHL-10018-11 Effect of aging on beating heart cells in
culture (rats)
POlHL-1 1351-12 0015 Cellular and molecular
mechanisms of myocardial function - Effects of hypoxia
and ischemia on ion exchange and heart function (rabbits)
POlHL-14414-07 0008 Environmental Influences on
cardiorespiratory and cellular functions - Energetics of
swimming (human)
ROlHL-14644-05 Optimization diastolic augmentation and
systolic sink (dogs)
RClHL-14e93-07 Survival value of physiological responses
to hypoxia (dogs)
POlHL-15194-07 0020 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation in
arteriographically normal arteries (human)
R01HL-15983-04 Regional myocardial blood (low (dogs)
ROlHL-17479-04 Blood storage -The production of
cardiotoxic material (dogs, human, swine)
P50HL-17667-04 0040 Study of ischemic heart disease -
Core biochemistry-Cardiac metabolism (human)
ROlHL-17808-03 Effect of altered oxygen affinity on
oxygen transport (human, rats)
ROlHL-18206-04 Regulation of metabolism in oxygen
deficient hearts (rats)
POlHL-19737-02 0005 Cellular and molecular aspects of
respiratory physiology - Interaction of respiratory exchanges
and blood gas parameters (human, animals)
Heart lactate dehydrogenase -The complex
Lactate metabolism in the lung (rats)
Cardiac adaptation to aging and stress
R01HL-20I 16-01
with NADH (pig)
" ROlHL-20566-02
R23HL-21393-01
(rats)
ROlHL-22101-02 Hormone substrate interaction in diabetic
myocyte (dogs, rats)
R01HL-2223I-02 Modulation of calcium control of cardiac
myofibrils (rats)
RClHL-22281-01 Microprobe analysis and metabolite
levels of ischemic mycardium (dogs)
R23HL-22575-01 Factors modifying cardiac digoxin effects
and content (dogs, cats)
ROlHL-23166-01 Pathology of mitochondria in ischemic
myocardium (rats, cattle)
ROlHL-23205-01 Contraction of pulmonary vascular
smooth muscle (cat)
ROlHL-23240-01 Pulmonary vascular muscle metabolism
and contractility (rats, cattle)
ROlHL-23618-01 Substrate metabolism in isolated
myocytes in shock (dogs, rats, guinea pigs)
FATTY ACIDS, LEVULINIC ACID
ROlHL-19517-03 Synthesis of inhibitors for the study of
renal renin (dogs, monkeys)
FATTY ACIDS, LINOLEIC ACID
R01HL18239-03 Dietary fat composition and
prostaglandin synthesis (rats)
ROlHL-19997-02 Prostaglandin precursors and intestinal
vasculature (cats, rabbits)
ROlHL-20411-03 Platelet fatty acid metabolism in
diabetes (rat, rabbit, guinea pig)
RDlHL-22847-01 Test for adherence to diets rich in
llnoleic acid
FATTY ACIDS, LINOLENIC ACID
" POlHL-06835-17 0014 Cardiovascular disease - Dietary
induction of severe atherosclerosis and its prevention
(dogs)
POlHL-06835-17 0016 Cardiovascular disease - Metabolic
interactions to polyunsaturated fatty acids in atherogenic
diet (dogs)
FATTY ACIDS, MEVALONIC ACID
ROlHL-06222-18 Clinical and laboratory studies in lipid
metabolism (human, mammals, non-human)
ROlHL-12745-10 Enzymes and inhibitors of cholesterol
biosynthesis (rats, human, swine)
FATTY ACIDS, OLEIC ACID
** POlHL-06835-17 0019 Cardiovascular disease - Fatty
acid distribution (rats)
POlHL-082 14-15 0030 Chemical and biological properties
of lipids - Fatty acid biosynthesis in plant cell cultures and
in plants
FATTY ACIDS, PALMITIC ACID
ROlHL-12530-10 Emphysema -Respiratoiy function in
disease (human, dogs, rats)
ROlHL-13921-07 The lung as a metabolic organ (animals)
ROlHL-14730-07 Fatty acid beta-oxidation in normal and
Ischemic hearts (rabbits)
** ROlHL-228 13-01 Palmitylcarnitine inhibition of ion pumps
in ischemia (dogs)
** ROlHL-23161-01 0002 Biology of myocardial ischemia -
Palmitylcarnitine Inhibition of ion pumps in myocardial
ischemia (dog, sheep)
FATTY ACIDS, PROPIONIC ACID
SEE ALSO FATTY ACIDS, LACTATES
POlHL-08214-15 0041 Chemical and biological properties
of lipids - Physico-chemical regulation of enzymes in lipid
metabolism
FATTY ACIDS, PYRUVATES
SEE ALSO OXIOOREDUCTASES, PYRUVATE DEHYDROGENASE
SEE ALSO OXIOOREDUCTASES, PYRUVATE OXIDASE
POlHL-08899-14 0012 Tolerance to respiratory gases in
health and disease - High oxygen for normal brain
metabolism and circulation in man
ROlHL-15983-04 Regional myocardial blood flow (dogs)
ROlHL-18984-01 P50 effect on exercise limit in stable
angina (human)
ROlHL-21209-02 Alterations of metabolism in ischemic
myocardium (swine)
FATTY ACIDS, SATURATED FATTY ACIDS
SEE ALSO LIPIDS, FATS, SATURATED FATS
ROlHL-12399-13 Specific fatty acids and cholesterol
metabolism (gerbils, rats)
POIHL- 132 62-07 0015 Arterial wall in atherosclerosis -
Crosslinkage biosynthesis in aortic elastin and collagen
(animals)
ROIHL- 148 90-07 Platelet prostaglandins (human, rabbits)
P60HL-17269-04 0003 National heart and blood vessel
research and demonstration center - Atherosclerosis -Fatty
acid metabolism in cardiovascular tissue (human, chicken)
ROlHL-18636-02 Fatty acids and cholesterol transport
(rats)
R01HL-23598-01 Dietary fat, cholesterol and bile acid
turnover (rats)
FATTY ACIDS, STEARIC ACID
ROlHL-204 11-03 Platelet fatty acid metabolism in
diabetes (rat, rabbit, guinea pig)
ROlHL-215 13-02 Metabolism of trans fatty acids (human,
rats, swine)
FATTY ACIDS, TETRACOSANOIC ACID
ROlHL-024 77-23 Biosynthesis and function of lipids
(microorganisms, rats)
FATTY ACIDS, UNSATURATED FATTY ACIDS
SEE ALSO CARBOXYLIC ACIDS, ENOLATES
SEE ALSO FATTY ACIDS, ARACHIDONIC ACID
SEE ALSO FATTY ACIDS, LINOLEIC ACID
SEE ALSO FATTY ACIDS, LINOLENIC ACID
SEE ALSO FATTY ACIDS, OLEIC ACID
SEE ALSO LIPIDS, FATS, UNSATURATED FATS
ROlHL-01979-22 Arteriosclerosis in zoo animals on
controlled diets (animals)
ROlHL-03299-21 Dietary effects on cholesterol metabolism
(rats, rabbits)
** POlHL-06835-17 0016 Cardiovascular disease • Metabolic
interactions to polyunsaturated fatty acids In atherogenic
diet (dogs)
POlHL-082 14-15 0048 Chemical and biological properties
of lipids - Lipids in microorganisms and plants
ROlHL-09489-13 Myocardial lipid metabolism and
regulation (rats)
POlHL-13262-07 0015 Arterial wall In atherosclerosis -
Crosslinkage biosynthesis in aortic elastin and collagen
(animals)
ROlHL-14730-07 Fatty acid beta-oxidation in normal and
ischemic hearts (rabbits)
ROlHL-16029-05 Bio-organic chemistry of ozone, nitrogen
dioxide and tobacco smoke
P60HL-172e9-04 0003 National heart and blood vessel
research and demonstration center • Atherosclerosis -Fatty
acid metabolism in cardiovascular tissue (human, chicken)
ROlHL-17564-03 Unsaturated fats-Mode of
hypocholesterolemic action (minipig)
ROlHL-18239-03 Dietary fat composition and
prostaglandin synthesis (rats)
Fatty acids and cholesterol transport
Unsaturated fatty acid biosynthesis in
Metabolism of trans fatty acids (human,
ROlHL-18636-02
(rats)
" R01HL19936-02
the aorta (rats)
ROlHL-2 1513-02
rats, swine)
R23HL-22075-01 Metabolism of arachidonic acid in blood
vessels (chickens, mammals)
ROlHL-23598-01 Dietary fat, cholesterol and bile acid
turnover (rats)
FATTY ACIDS, UNSATURATED FATTY ACIDS,
PROSTAGLANDINS
SEE ALSO FATTY ACIDS METABOLISM, PROSTAGUNDINS
METABOLISM
SEE ALSO OXIOOREDUCTASES, PROSTAGUNDIN SYNTHASE
ROlHL-02262-23 Mechanisms regulating plasma proteins
and solutes (human, dogs)
ROlHL-03941-18 Uterine blood flow and changes in
pregnancy (sheep)
ROlHL-05062-18 Lipid metabolism in cultured cells
(human, rats, rabbits)
ROlHL-05883-18 0001 Reflex control of resistance and
capacitance vessels - Naturally occurring vasoactive
substances and the vascular neuroeffectors (dog)
** ROlHL-05883-18 0007 Reflex control of resistance and
capacitance vessels ■ Prostaglandins and skeletal muscle
blood flow (dogs)
POlHL-06285-18 0186 Cardiovascular-respiratory
physiology and biochemistiy - Leukocyte hormone receptors
and cyclic nucleotides (tissue culture)
" POlHL-06312-17 0046 Surgical cardiology - The
relationship of prostaglandins to heart disease
POIHL-06314-17 0047 Immunologic mechanisms in
cardiovascular disease - Role of intravascular coagulation
(human, animals)
POlHL-06314-17 0053
cardiovascular disease
Immunologic mechanisms in
Cellular functions controlled by
cyclic GMP (human, mice, guinea pigs)
POlHL-06314-17 G064 Immunologic mechanisms in
cardiovascular disease - Diabetic vascular disease (human,
rats, mice)
POlHL-06664-17 0043 Cardiopulmonary function in
remediable vascular disease - Alveolar hypoxic
vasoconstriction-Control and clinical significance (dog,
human)
POlHL-06835-17 0030 Cardiovascular disease - Synthesis
and pharmacology of angiotensin antagonists (rats, cats)
P01HL-Oe835-17 0031 Cardiovascular disease - Synthesis
of potent antagonist of pressor action of angiotensin II
(animals)
POlHL-06835-17 0063 Cardiovascular disease • Studies
on prostaglandins (human, rabbits)
ROlHL-08570-15 Pharmacologic and reflex influence on
vascular tone (dogs, rabbits)
ROlHL-08659-14 Myocardial performance and metabolism
in the newborn (sheep)
P01HL08805-15 0047 Regulation of ventilation and
pulmonary circulation - Extracranial metabolic control of
ventilation (dogs, goats)
ROlHL-10182-13 Circulatory function and electrolytic
metabolism (dogs, human)
POlHL-10342-13 0019 The integrated function of
respiration and circulation - Cerebral circulation and
metabolism (dogs)
POlHL-10342-13 0027 The integrated function of
respiration and circulation - Control of respiration -
Cardiovascular adjustment to hypoxia and carbon monoxide
POlHL-10342-13 0028 The integrated function of
respiration and circulation - Mediator release,
hemodynamics and respiratory function in anaphylaxis
(dogs)
ROlHL-10942-09 Study of genetic hypertension in rats
POlHL-11414-11 0004 Thrombosis and atherosclerosis
program - Platelet function and nonthrombogenic surfaces
(human)
ROlHL-11614-11 Trace elements in nutrition (chickens,
rats, human)
POlHL-11678-11 0059 Cardiovascular dynamics and their
control Basic hemodynamics (dogs, rats)
ROlHL-11880-10 Physiology and pathologyof blood
platelets (human, dogs)
POlHL-12373-10 0005 Cardiopulmonary physiology and
pathophysiology - Characterization of fetal and neonatal
myocardium (human, cats)
ROlHL-12677-10 Surgical physiologic studies of isolated
kidneys (dogs, rats)
POlHL-12738-10 01 U Physiologic pharmacology and its
clinical applications - Cardiovascular pharmacology (dogs)
ROiHL-12775-08 Cerebral microcirculation (mice)
ROlHL-12827-08 Regulation of sodium excretion (dogs,
rats)
ROlHL-12990-09 Control of antidiuretic hormone secretion
and metabolism (dogs, rats, rabbits)
ROlHL-13193-09 Pathophysiology of post-traumatic and
shock states (rodents, dogs)
POlHL-13262-07 0011 Arterial wall in atherosclerosis •
Role of hypertension in atherosclerosis (human, monkey,
dog)
(contd)
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
••"n^ntBd sienificantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
fAT
" POIHl 13262 0/ 002? Arlnntl wall In ilhttoscltiosil
M»ch«nlsmj ol plalnlet piotlt||laiioln loimation
ROIHl 1331b 08 Dlipoiition ol vatotcllva hormonat in
inannnalian lunt tials. labhiti. human)
** ROIHL US95as Ranin and vasculai hypai laactivity in
tiypartansion (human, lats)
ROIHI 13nb08 MyocaidMl adonyl cyclase (ralis)
POIHI 1373/0/ OOJl Assisted ciiLUlalion MyOdiidiul
Ischamia Biorhrmical changes (dots)
ROIHL 13936 06 Microvascular responses in hypertension
(human, lats)
P50HL 14141 0!) 0003 SCOR lor alherosclero:iis in
childhood Detection ol abnonnalities in lipid inelabolism
(human, rabbits, rats)
PSOHL 1414/ 08 0001 Speci.^iii«d center ol losearch in
thrombosis Role ol aspirin, other anti platelet <i|jents in
platelet lunction (rat, human)
" PSOHL 141130/ 0012 Johns HopMns Lung Center--
Chronic diseases ol airways Aspirin intolerance in
reversible lung disease (human)
P50HL 141530/ 0013 Johns Hopkins Lung Center
Chronic diseases ol airways Pulmonory mechanics and
mediators ot allergic reactions (guinea pigs, human)
PSOHL- 14 153 07 0014 Johns Hopkins Lung Center -
Chronic diseases o< airways - Mediator release in asthma
(human)
PSOHL-1415908 0020 Specialued center ol research in
hypertension - Reninmineralocorticoid system in
hypertension (human, rat. dog)
** PSOHL-14187-07 0012 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses Vasoactive
mediators in pulmonary disease (human, animal)
** P50HL-14192 08 0003 Specialized center ol research in
hypertension - Prostaglandins as mediators of renin
secretion (human, dog)
*• P50HL-14214-07 0026 Newborn lung center for hyaline
membrane disease - Hemodynamic studies of HMD-
Prostaglandins production and blockers (lambs)
P50HL 1421407 0031 Newborn lung center for hyaline
membrane disease - Essential fatty acid deficiency and
HMD (human)
PSOHL- 142 17-08 0058 Specl3li2ed center of research in
thrombosis - Mechanisms of induction and inhibition of
platelet reaction (human, pig)
P50HL-14230-07 0097 AyS SCOR -Lipids, atherosclerosis
and thrombosis - Studies of circulating platelet aggregates
(human)
P01HL14388-07 0157 Regulation of the circulation In
pathological states - Autoregulation of renal blood flow and
distribution in sodium excretion control
POlHL-14388-07 0179 Regulation of the circulation in
pathological states - Cultured muscle cells and their cross-
Innervation in vitro (rats, sheep)
POlHL-1438807 0180 Regulation of the circulation in
pathological states - Regulation of cerebral blood flow
(dogs, monkeys)
P01HL1438807 0183 Regulation of the circulation in
pathological states - Vasopressin in cardiovascular
regulation (dogs, rats)
** POlHL-1438807 0225 Regulation of the circulation in
pathological states - Release of renal prostaglandins by
saluretic-diuretic agents (dogs)
POlHL-14388-07 0230 Regulation of the circulation in
pathological states - Effects of indomethacin in patients
with carcinoid syndrome
** P01HL14388-07 0231 Regulation of the circulation in
pathological states - Mechansim of cutaneous
vasodilatation in Paget's disease of bone
POlHl-14388-07 9002 Regulation of the circulation in
pathological states - Core immunoassay laboratory (rabbits)
** ROlHL-14397-07 Hypertension -Angiotensin and
prostaglandin pharmacology (animals)
POlHL-14414-07 0015 Environmental influences on
cardiorespiratory and cellular functions - Control of the
cardiovascular system (dogs)
ROlHL-14456-07 Lung metabolism-Enzymes in the
pulmonary circulation (human, animals)
** POlHL-14985-07 0011 Adaptation to hypoxia •
Prostaglandins in the control of the pulmonary circulation
(animals)
POlHL-1498507 0012 Adaptation to hypoxia - Direct
effect of hypoxia on pulmonary vascular smooth muscle
(rats, dogs)
POlHL-14985-07 0015 Adaptation to hypoxia - Pregnancy
at high altitude (human, animals)
ROlHL-1500207 Biochemical pharmacology of guanylate
cyclase in lung (cattle, rats)
ROlHL-15215-06 Role of complement in intravascular
coagulation (rabbits, mice)
** ROIHL- 153 78-06 Ultrasfructure of antihypertensive
prostaglandins
** fiOlHL-15447-06 Vascular role of prostaglandin and :ycl!c
nucleotides (rats)
RClHL-15562-05 Regulation of skeletal muscle blood flow
(dogs)
** ROlHL-15580-06 Humoral control of pulmonary and
systemic circulation (animals)
** ROlHL-15677-06 Autonomic nervous system function in
bronchial asthma (human, guinea pig. rabbit)
POlHL-15832-06 0007 Chemical-structural predispositions
to lung injury - Inactivation of vasoactive agents by the
lung (human, rats. cats, dogs)
2) I
ROIHL 15839 05 Physiolo|l<.«l rule ul i>oifinin .ind
kallikiein (animals)
POIHL 1638/ 04 0005 Iht blood vessel and
thrombogene\ls Fluid enflneiring coniidarilions in
lhrolnbogonl!^is
ROIHl 16454 03 Vascular muscle reactivity in
hypciteiision (human, rats)
-■ R0IHMb489 04 Keiial prostaglandins Synthesis and
lunction (human, dogs, rats)
** ROIHL 16496 04 Prostaglandins and renin exporiinental
hypertensinn (rabbits)
ROIHL 16634 13 Rcgulatiun ol metabolism in fibroblasts
and platelets (hum<iii, labbils. sheep)
ROIHL 16714 05 Endothelial cell cuminunicatmn in
homeostasis (human, mammals)
ROIHL 16760 05 Dynamic control of coronary blood flow
(dogs)
" ROIHL 17341 03 Practical total synthesis of
prostaglandins
ROIHL 17355 04 Pulmonary vascular adjustments in
circulatory collapse (dogs, rats)
POIHL 17382 05 0003 Chemical mediators of acute
pulmonary disorders Chemical mediators relevant to
allergic reactions (human, guinea pigs)
ROIHl 17401 03 Mechanisms in angiotensin induced
hypeitens:on (cih, dogs)
ROIHL 17458 04 Renal control of sodium excretion (rats)
ROlHL-17487 04 Adrenergic vasorcgulation interactions in
hypertension (human)
R01HL17516-04 Role of androgen as a risk factor in
atherogenesis (human, animals)
P50HL- 17646 04 0016 Study ot ischemic heart disease
Humoral factors in ischemic heart rhythm, mechanical
performance (dog, rabbit)
P50HL-17651-04 0045 Ischemic heart disease specialized
center of research Peripheral vascular studies-
Pharmacology (dogs, human)
ROlHL-17705-04 Kallikreinkinin system in hypertension
(human, rats, dogs)
ROIHL 17729-04 Stimulus-response coupling in platelets
(human)
ROIHL 17759-03 Studies of myocardial reactive hyperemia
(dogs, human)
R01HL-17768-04 Development of collateral ventilation
(dogs, fish, horses)
M POlHL-17871 04 Kidney, sodium, cardiac output, arterioles
and hypertension
♦* POIHL 17871-04 0009 Kidney, sodium, cardiac output,
arte.'ioles and hypertension - Kidney, sodium, cardiac
output, arterioles and hypertension
** POlHL-17871-04 00!0 Kidney, sodium, cardiac output,
arterioles and hypertension - Renal prostaglandins
metabolism in hypertension (rats, dogs)
" R01HL-I8070-04 Regulation of infrapuimonary always
and vessels (human, animals)
ROIHL 18191-04 Models of hypoxic pulmonary
hypertension (cattle, minipigs)
** ROlHL-18239-03 Dietary fat composition and
prostaglandin synthesis (rats)
** ROlHL-18259-03 Controlled intratissue release of
prostaglandins
P50HL 18318 03 0003 Pathogenesis and complications of
hypertension - Core biochemical laboratory
P50HL-183 18-03 0015 Pathogenesis and complications of
hypertension - Cultured smooth muscle cells and
microvessel metabolism (mammals)
POlHL-18575 03 0011 Mechanisms of vascular changes
in hypertension - Chemistry laboratory core facility
POlHL-18576-03 0001 Thrombosis research program
project - Platelet damage from physical forces and
artificial surfaces (human)
** ROlHL-18579-03 Vasoaciiue hormones and blood pressure
regulation (dogs. rats, rabbits)
ROlHL-18586-03 Role of platelet lipids in hemostasis and
thrombosis (human)
ROIHL 18725 03 Light-scattering studies of the sickling
process (human)
POIHL 18827 02 0003 Platelet vessel wall interactions in
thrombogcnesis - Tumor cell and platelets in
thrombogenesis and metastasis (human, animals)
POlHL-18827-02 0005 Platelet vessel wall interactions in
thrombogenesis - Platelet vessel wall interactions in
thrombogenesis (human)
P50HL-18828-03 0008 Specialized center of research in
thrombosis - Biochemistry. physiology-Platelets and
subcellular platelet particles (human)
** ROiHL-18845-04 Regulation of renal circulation and salt
excretion (rats, dogs)
** SOlHL-18875-03 Angiotension. prostaglandins, pressure
and the kidney (rats)
** ROlHL-1897902 Mechanisms in local regulation of
coronary flow (rabbits)
R01HL19055-03 Platelet function during extracorporeal
perfusion (human, mammals)
ROlHL-19057-03 Catecholamines and cyclic AMP in
cardiovascular system (rats, dogs)
*' ROlHL-19134-04 Angiotensin, prostaglandins, adrenergic
interactions (rats, rabbits)
** P50HL-191 53-02 0001 SCOR-Pulmonary edemas -Eitobgy,
pathogenesis - Prostaglandins and the lung circulation
(sheep)
'Excludes routine methodology OR covers only general projects which precltide indexing at the specific level.
••Oriented significantly to above subject.
M Grant has subprojects deschhing s
See Appendix for investigator's name
fAI
P50HI 19156 02 0005 Pulmonary SCOR Chronic diMiMi
ol airwayt Vagel leuplori in Iht iirwty (pilhihtl injury
• nd inligmi (dog, c«l. rabbit)
P50HI 19185 02 0003 Pulmonary SCOR Neonatal
retpimlory diitroi tyndromei Factor-. •Iftcling toimilion
and release ol pulmonary turfacKnl in fetal liiinbt
*• ROIHI 1920203 Adenosine, proiltglindint in rtlatwn to
coiunary How (guinea pigs)
" ROIHL 19218 03 Local regulation of coronary How by
prostaglandins (rabbits)
•• ROIHL 19229 02 Prostaglandins and hyperttniion (human.
rats. dngs. labhil-.)
POIHL 19242 0? 0003 Study of vascular imooth mutcle
Vasoactive metabolites from vascular muscle and
parenchymal tissue (animal)
POIHl 19242 02 0004 Study ol vascular imooth muscle
Cyclic nucleotide metabolism in smooth muscle cultures
(human, rats)
POIHI 1924202 0007 Study of vascular smooth mutcle
NE release in and reactivity of vascular smooth muscle
(animals)
ROIHL 19287-03 The antihypertensive lunction ol the
renal medulla (human, rats, rabbits)
ROIHL 19374 03 Pharmacology of kinins in cardiovascular
disease (rats, rabbits)
ROIHL- 194S5-03 Role of endothelial cells in vascular
permeability (tissue culture)
ROlHL-19673-03 Surgical aspects ol shock and hypoxia
(dogs, monkeys, rats)
*• POIHL 19717-02 0007 Response of the lung to injury
Cellular level studies of prostaglandin like molecules
(cattle)
** POIHL 19717-02 0013 Response of the lung to injury
Handling of biologically active substances by the diseased
lung (guinea pigs)
** POIHL 19717 02 0037 Response of the lung to injury ■
Catecholamines, prostaglandins and nucleotides m
pulmonary function (animals)
POlHL-19737-02 0002 Cellular and molecular aspects of
respiratory physiology Airway smooth muscle in health
and disease (human, animals)
POlHL-19737-02 0009 Cellular and molecular aspects of
respiratory physiology Regulation of tissue oxygen tension
and body carbon monoxide stores (human, dogs)
ROlHL-1983603 Kinin inhibitors detected by use of
receptors (cattle)
ROlHL-1987003 Hypertensive progeny-Physical and
humoral precursor search
** ROlHL-19997-02 Prostaglandin precursors and intestinal
vasculature (cats, rabbits)
ROlHL-2005402 Cultured blood vessel cells
Pathophysiology (human, animals)
ROlHL-20079-02 0002 Thromboresistant material
Thromboresistant materials (sheep)
ROlHL-20251 02 A novel approach to nonthrombogenic
polymer surfaces (sheep, cattle)
ROlHL-20429 03 Study of effects of diabetes reactivity
(miniature pigs, rats)
ROlHL-20719-02 Cold induced pulmonary hypertension
(cattle)
*' ROlHL-20787-02 Thromboxanes and prostaglandins-
Biochemical pharmacology (rabbits, human)
ROlHL-2089503 0007 Cineangiogiaphic studies of
cardiovascular system Determinants of collateral
for.nation (dogs, hamsters)
ROlHL-20989-01 Pathophysiology of bronchial asthma
(sheep, dogs)
ROltiL-21076-02 Lung fluid, procein exchange after
hemorrhagic shock (sheep)
R23HL-2I089-02 Localization of mediators in dispersed
lung cells (guinea pigs, human)
ROIHL-21 158-02 Cardiac receptors with vagal C-fiber
afferents (cats)
** ROlHL-2 12 72-02 Sodium homeostasis and renal
prostaglandins (dogs)
R23HL-21291-02 Reninmineralocorticoid axis in
hypertensive diabetics (human)
•* ROlHL-21308-01 Prostaglandins and local control of the
circulation (rats, dogs)
R23HL-21409-02 Perinatal control of the ductus arteriosus
(sheep)
ROlHL-21460-02 Lipoproteins, hemostasis and
atherosclerosis (human, rabbits)
ROlHL-21523-01 Hemodynamic effects of dietary sodium
in man
** R01HL-21568-02 Cell biology of the alveolar-capillary unit
(animals)
** ROlHL-21764-01 Ultramicroanalysis of prostaglandins and
related compounds (rats)
** R01HL-22025-01 Endogenous prostaglandins in asthma
** ROlHL-22069-02 Experimental renal arterial hypertension
(dogs)
R23HL-22075-01 Metabolism of arachidonic acid in blood
vessels (chickens, mammals)
POlHL-22163-01 0003 Surface thrombogenesis -
Mechanisms and prevention - In vivo mechanisms of
biomaterial thrombogenesis and its prevention (baboons)
ROIHL-22172-01 Hypotension, renal ischemia and effect of
mannitol (dogs, rats)
ROlHL-22177-02 Mechanisms of control of pulmonary
smooth muscle (dogs)
(contd)
pocific research aspects.
and grant number.
FAT
212
FAT
ROlHL'22216-02 Vascular mechanisms in renal
hypertension (dogs)
ROlHL-22219-01 Prostacyclin and peroxides In blood and
membrane disease
ROlHL'22244-01 Cardiopulmonary bypass and the
vascular endothelium (dogs)
R23HL-22309-01 Cardiovascular pharmacodynamics In
Immature dogs
R23HL-22346-01 Hematological injury and pulmonary
dysfunction (human, mammals)
ROlHL-22470-01 Liposome myocardial uptake In Infarct
and ischemia (dogs, rats, mice)
R01HL-224g2-01 Circulatory hemodynamics and sodium
excretion (dogs)
ROlHL'22520-01 Pulmonary vascular response to group B
Streptococci (human, mammals)
ROlHL-22555-01 Structure and function of platelet
activating factor (rabbits, human)
R01HL-225e3-02 Prostaglandins, the kidney and
hypertension (rats)
POIHL 22602-01 0001 Pathophysiology of the
endothelium - Platelet-endothellal Interactions In vitro
(human, cattle)
POlHL-22602-01 0003 Pathophysiology of the
endothelium - Mechanisms of endothelial proliferation
(human, animals)
R01HL-2283e'01 The spontaneously hypertensive kidney
(rats)
ROIHL 22868-01 Presynaptic regulatory mechanisms in
hypertension (rats, dogs)
R23HL-22882-01 Modulation by disease of effect of
furosemlde In man
ROlHL-22951-01 Studies on the affect of vitamin E on
platelets (human, rats)
** ROlHL-23585-06 Pharmacologic control of hypersensitivity
phenomena (human)
ROlHL-23982-01 Control of coronary flow by carbon
dioxide tension (dogs)
** NOIHV 72943-01 Prostaglandin and kallikrein kinin system
antagonists
** NOlHV-72944-02 Prostaglandin and kallikrein kInIn
antagonists
FATTY ACIDS, UNSATURATED FATTY ACIDS,
PROSTAGLANDINS ANALOGS
** ROlHL-15378-06 Ultrastructure of antihypertensive
prostaglandins
FATTY ACIDS, UNSATURATED FATTY ACIDS,
THROMBOXANES
SEE ALSO FATTY ACIDS METABOLISM. PROSTAGUNDINS
METABOLISM
ROlHL-05062-18 Lipid metabolism In cultured cells
(human, rats, rabbits)
** POlHL-06835-17 0063 Cardiovascular disease - Studies
on prostaglandins (human, rabbits)
ROIHL- 11880-10 Physiology and pathology of blood
platelets (human, dogs)
ROlHL-1 1897-11 Pathogenesis of experimental
atherosclerosis (rabbits, guinea pigs)
P50HL-14147-08 0001 Specialized center of research in
thrombosis - Role of aspirin, other anti-platelet agents In
platelet function (rat, human)
•* ROlHL-15378-06 Ultrastructure of antihypertensive
prostaglandins
ROIHL- 15580-06 Humoral control of pulmonary and
systemic circulation (animals)
** ROlHL-18070-04 Regulation of intrapulmonary airways
and vessels (human, animals)
ROlHL-18239-03 Dietary fat composition and
prostaglandin synthesis (rats)
ROlHL-18718-04 Prostaglandin precursors and vascular
reactivity (dogs)
ROlHL-20787-02 Thromboxanes and prostaglandins-
Biochemical pharmacology (rabbits, human)
ROlHL-20818-02 Platelet storage at 22 degrees C
(human)
ROlHL-21523-01
In man
ROlHL-21764-01 Ultramlcroanalysls of prostaglandins and
related compounds (rats)
ROIHL 22026-01 Endogenous prostaglandins In asthma
R23HL-22075-01 Metabolism of arachidonic acid in blood
vessels (chickens, mammals)
ROlHL-22087-02 Humoral mediators of pulmonary
inflammation (guinea pigs)
" ROlHL-22225-01 Hormonal legulation of blood pressure
and blood flow (human, animals)
** ROlHL-22527-01 Prostacyclin-thromboxanes in the
cardiovascular system (human, rabbits)
** ROIHL 22946-01 Prostaglandins, platelet aggregation and
vasoactivity (human, rats, rabbits)
FATTY ACIDS BIOSYNTHESIS
** ROlHL-02477-23 Biosynthesis and function of lipids
(microorganisms, rats)
POlHL-08214-15 0006 Chemical and biological properties
of lipids - Analysis and properties of lipids
** POlHL-08214-15 0030 Chemical and biological properties
of lipids - Fatty acid biosynthesis in plant cell cultures and
in plants
ROlHL-08570-15 Pharmacologic and reflex influence on
vascular tone (dogs, rabbits)
Hemodynamic effects of dietary sodium
ROlHL-11802-10 Cardiovascular surgical research (dogs.
sheep, swine, cats, monkeys)
ROlHL-11897-11 Pathogenesis of experimental
atherosclerosis (rabbits, guinea pigs)
R01HL-13715-a8 Myocardial adenyl cyclase (rats)
P50HL-14164-07 0035 A/S SCOR -Comparative and
experimental atherosclerosis - Lipid metabolism-Interaction
with arterial metabolism (monkey, pigeon)
P50HL-14214-07 0015 Newborn lung center for hyaline
membrane disease - Hormone effect on cyclic nucleotide
lipid synthesis in developing lung (animal)
ROlHL-14595-07 Primary disorders of platelet function
(human, rats)
** R01HL14890-07 Platelet prostaglandins (human, rabbits)
ROlHL-16029-05 Bio^)rganic chemistry of ozone, nitrogen
dioxide and tobacco smoke
** ROlHL-16489-04 Renal prostaglandins-Synthesis and
function (human, dogs, rats)
** ROlHL-16524-02 Selective Inhibitors of prostaglandin
biosynthesis (dogs)
ROlHL-16628-05 Regulation of lipid metabolism (rats)
R01HL-16e34-13 Regulation of metabolism In fibroblasts
and platelets (human, rabbits, sheep)
** P60HL- 172 69-04 0003 National heart and blood vessel
research and demonstration center - Atherosclerosis -Fatty
acid metabolism in cardiovascular tissue (human, chicken)
PSOHL-17646-04 0016 Study of ischemic heart disease -
Humoral factors In Ischemic heart rhythm, mechanical
performance (dog, rabbit)
** P50HL-17682-04 0021 Study of ischemic heart disease •
Prostaglandin biosynthesis in blood vessels from Ischemic
myocardium (rat. sheep)
** ROlHL-17921-04 Peroxy radicals to prostaglandins in
vessels and lung
ROlHL-18181-04 Surfactant metabolism-Alveolar cells and
lung disease (mice, rabbits)
ROlHL-18878-03 Familial hypercholesteremia -Studies of
fibroblasts (human)
** ROlHL-18938-03 Pulmonary fatty acid and phospholipid
metabolism (rats)
ROlHL-19010-03 Metabolism and cell biology of lung
surfactant system (rabbits, sheep)
ROlHL-19066-03 Synthesis and evaluation of
prostaglandin metabolites (guinea pigs)
ROlHL-192 18-03 Local regulation of coronary flow by
prostaglandins (rabbits)
POlHL-19242-02 0002 Study of vascular smooth muscle -
Vascular smooth muscle response to serum lipoproteins
(rats)
** ROlHL-19936-02 Unsaturated fatty acid biosynthesis in
the aorta (rats)
** ROlHL-19997-02 Prostaglandin precursors and intestinal
vasculature (cats, rabbits)
** ROlHL-20783-02 Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
** ROlHL-20794-02 Prostaglandin synthesis in human
platelets (also in sheep, rabbit)
** R23HL-21066-02 Angiotensin and prostaglandin control of
aldosterone (rats)
R23HL-2125101 Metabolism of neutral lipids in the
pulmonary alveolus (rabbits)
ROlHL-21272-02 Sodium homeostasis and renal
prostaglandins (dogs)
R23HL-22075-01 Metabolism of arachidonic acid In blood
vessels (chickens, mammals)
** ROIHL-22946-01 Prostaglandins, platelet aggregation and
vasoactivity (human, rats, rabbits)
ROlHL-231 59-01 Regulation of lipogenesis by
polyunsaturated fats (rats, chicks)
** ROlHL-23602-01 Physiology of renin, aldosterone and
prostaglandin (human, rats, dogs)
** NOlHV-72945-03 Develop prostaglandin synthesis and
receptor antagonists
FATTY ACIDS METABOLISM
SEE ALSO FATTY ACIDS BIOSYNTHESIS
SEE ALSO FATTY ACIDS TRANSPORT (GENERAL)
ROlHL-03734-18 Metabolism of arterial tissue In
atherosclerosis (rabbits)
** POlHL-06308-18 0040 Mechanisms and therapy of
circulatory disease - Metabolism and fatty acid utilization-
Heart electrical stability (rats, dogs)
** P01HL-0683S-17 0016 Cardiovascular disease - Metabolic
interactions to polyunsaturated fatty acids in atherogenic
diet (dogs)
POlHL-082 14-15 0030 Chemical and biological properties
of lipids - Fatty acid biosynthesis In plant cell cultures and
in plants
POlHL-08214-15 0048 Chemical and biological properties
of lipids - Lipids In microorganisms and plants
** ROlHL-09489-13 Myocardial lipid metabolism and
regulation (rats)
ROlHL-100 18-11 Effect of aging on beating heart cells in
culture (rats)
** POlHL-1 13 10-12 0080 Mechanisms of cardiovascular
disease - Metabolism of the hypertrophied myocardium
(human)
** POlHL-12373-10 0006 Cardiopulmonary physiology and
pathophysiology - Fatty acid metabolism -Regulation,
implications (human, mammals, birds)
ROlHL-12530-10 Emphysema-Respiratory function in
disease (human, dogs, rats)
" ROlHL-12745-10 Enzymes and inhibitors of cholesterol
biosynthesis (rats, human, swine)
** ROlHL-13028-09 Regulation of myocardial fatty acid
metabolism (rats)
** ROlHL-13302-09 Uptake and metabolism of lipids by the
liver (rats)
P50HL-14217-08 0059 Specialized center of research in
thrombosis - Energy metabolism and platelet function
(human)
P50HL-14230-07 0092 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Tissue lipids -Cell culture studies
(human)
P50HL-14230-07 0093 A/S SCOR-Lipids. atherosclerosis
and thrombosis - Clinical studies involving cellular lipid
content (human)
ROIHL 14706-07 Fetal hearts in organ culture (mice)
** ROlHL-14730-07 Fatty acid beta-oxidation in normal and
ischemic hearts (rabbits)
*• ROlHL-15376-06 Intermediary metabolism of sterols (mice)
** ROlHL-15813-05 Cardiac anoxia-Protective effect of
carbohydrate (dogs)
ROlHL-15930-06 Hormonal control of lipid and lipoprotein
synthesis (rats)
** P60HL- 17269-04 0003 National heart and blood vessel
research and demonstration center - Atherosclerosis -Fatty
acid metabolism in cardiovascular tissue (human, chicken)
P60HL- 17269-04 0018 National heart and blood vessel
research and demonstration center - Mitochondria and
energetics (rabbits, dogs)
P50HL- 17646-04 0009 Study of Ischemic heart disease -
Regional metabolic derangements Indicating ischemia
(rabbit, dog, human)
P50HL-17667-04 0012 Study of ischemic heart disease -
Biochemistry of normal and ischemic heart-Glycolysis (rats)
P50HL-17667-04 0040 Study of ischemic heart disease -
Core biochemistry-Cardiac metabolism (human)
** ROlHL-17895-04 Myocardial function and metabolism
following ischemia (rats)
** ROlHL-18089-04 Fatty acid metabolism in heart and its
regulation (swine, rats)
ROlHL-18176-02 Effect of thyroid hormone r
cardiac cells (rats)
** ROlHL-18206-04 Regulation of metabolism in oxygen
deficient hearts (rats)
P50HL-18318-03 0015 Pathogenesis and complications of
hypertension - Cultured smooth muscle cells and
microvessel metabolism (mammals)
" POlHL-19737-02 0001 Cellular and molecular aspects of
respiratory physiology - Fatty acid metabolism In type II
alveolar cells (rats)
ROlHL-20313-02 Surface-induced thrombosis -Modification
of albumin variants (human, goat)
ROlHL-20388-03 Regulation of protein turnover in diabetic
heart (rat)
ROlHL-20401-03 Relationship of insulin to catechol
cardiomyopathy (rabbit, pig)
** ROlHL-20411-03 Platelet fatty acid metabolism in
diabetes (rat. rabbit, guinea pig)
ROlHL-20484-03 Effects of diabetes on cardiac function
and metabolism (rats)
ROlHL-20909-02 Clofibrate-enhanced lipid oxidation by
peroxisomes (rats)
" ROlHL-21209-02 Alterations of metabolism in ischemic
myocardium (swine)
R23HL-21251-01 Metabolism of neutral lipids in the
pulmonary alveolus (rabbits)
ROlHL-21697-01 Myocardium infarct sizing by 82Rb
emission tomography (dogs, human)
** R23HL-22075-01 Metabolism of arachidonic acid in blood
vessels (chickens, mammals)
ROlHL-23142-01 Mechanisms of membrane injury in
myocardial ischemia (dog)
ROlHL-23161-01 0001 Biology of myocardial ischemia -
Mitochondrial lipid metabolism and cardiac ischemia (rat,
dog)
FATTY ACIDS METABOUSM, PROSTAGLANDINS
METABOLISM
ROlHL-08570 15 Pharmacologic and reflex influence on
vascular tone (dogs, rabbits)
ROlHL-11802-10 Cardiovascular surgical research (dogs,
sheep, swine, cats, monkeys)
" ROlHL-11897-11 Pathogenesis of experimental
atherosclerosis (rabbits, guinea pigs)
ROlHL-13715-08 Myocardial adenyl cyclase (rats)
P50HL-14147-08 0001 Specialized center of research in
thrombosis - Role of aspirin, other anti-platelet agents in
platelet function (rat, human)
P50HL-14147-08 0012 Specialized center of research in
thrombosis - Tissue culture study of arterial cells (human,
hamster)
P50HL-14153-07 0012 Johns Hopkins Lung Center-
Chronic diseases of airways - Aspirin intolerance in
reversible lung disease (human)
P50HL-14187-07 0012 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses - Vasoactive
mediators in pulmonary disease (human, animal)
P50HL-14217-08 0057 Specialized center of research in
thrombosis - Pharmacology-Platelet biochemistry (human,
animal)
Primary disorders of platelet function
ROlHL-14595-07
(human, rats)
ROlHL-14890-07
Platelet prostaglandins (human, rabbits)
(contd)
'Excludes routine melhodotogy OR covers only general projects which preclude indexing at the specific level.
**OTierTted significantly to above subject.
M Grant has subpiojects describing specific research aspects.
See Appendix for investigator's name and grant number.
FAT
7) J
Prostaglandin piscursots and vasculai
ROIHl l6U;f9 0ti Biooiianic chtmistiY ol o/one. nitroitn
dioaidt and tobacco smoka
ROIHl 1648904 Ranal piostailandins Synthesis and
function (human, dogs, tats)
ROtHl 16S24 0? Salactiva inhibitors ol prostaglandin
biosynthesis (dogs)
PSOHl 17646 04 0016 Study ol ijchamlc hatrt dISMU
Humoral laclois in ischamic heart rhythm, mechanicti
pertormance (dog. rabbit)
PbOHL 17682 04 0021 Study ol ischemic heart disease
Prostaglandin biosynthesis in blood vessels Irom ischemic
myocardium (rat. sheep)
ROIHL 1792104 Permy radicals to prostaglandins in
vessels and lung
ROIHL 18718 04
reactivity (dogs)
ROIHL 19066 03 Synthesis and evaluation ol
prostaglandin metabolites (guinea pigs)
ROIHL 1921803 Local regulation ol coronary How by
prostaglandins (rabbits)
R01HL'1999?'02 Prostaglandin precursors and intestinal
vasculature (cats, rabbits)
ROIHL'20783 02 Airway reactivity B adrenoceptors and
prostaglandins (guinea pigs)
ROIHL 2079402 Prostaglandin synthesis in human
platelets (also in sheep, rabbit)
R23HL 21066 02 Angiotensin and prostaglandin control ol
aldosterone (rats)
ROIHL 2127202 Sodium homeostasis and renal
prostaglandins (dogs)
ROIHL 2222501 Hormonal regulation ol blood pressure
and blood How (human, animals)
ROIHL 2252701 Prostacyclin-thromboxanes in the
cardiovascular system (human, rabbits)
ROIHL'22784'OI Ductus arteriosus closure--An arterial
lesion model (rabbits)
R01HL2294601 Prostaglandins, platelet aggregation and
vasoactivity (human, rats, rabbits)
ROIHL'23114.01 Control of platelet aggregation in shock
(dogs, rabbits)
ROIHL'23602'01 Physiology ol renin, aldosterone and
prostaglandin (human, rats, dogs)
N01HV'72945-03 Develop prostaglandin synthesis and
receptor antagonists
ATTY ACIDS TRANSPORT (GENERAL)
R01HL-02751-21 Function and metabolism of serum
albumin (mammals, fish, amphibians)
ROlHL-12399 13 Specific fatty acids and cholesterol
metabolism (gerbils. rats)
** R01HL-14730-07 Fatty acid beta-oxidation in normal and
ischemic hearts (rabbits)
POlHL-18577-03 0003 Lipoproteins-Cell surface
interactions - Mechanism of lipid exchange in lipoproteins
and cell membranes
ROIHL 1863602 Fatty acids and cholesterol transport
(rats)
ROlHL-20308-02 Regulation of myocardial acylcarnitine
transport (rats)
ROlHL-22101'02 Hormone-substrate interaction in diabetic
myocyte (dogs, rats)
R01HL-231S9-01 Regulation of lipogenesis by
polyunsaturated fats (rats, chicks)
ROlHL'23618-01 Substrate metabolism in isolated
myocytes in shock (dogs. rats, guinea pigs)
FATTY LIVER
SEE LIVER DISORDERS. FATTY LIVER
FATTY TISSUE
SEE CONNECTIVE TISSUE, ADIPOSE
FECES
SEE GASTROINTESTINAL EXCRCTA, FECES
FECES ANALYSIS
SEE CHEMISTRY. CLINICAL. FECES ANALYSIS*
FEEDBACK, SENSORY
SEE SENSORY FEEDBACK
FEEDBACK CONTROL (BIOLOGICAL)
SEE INFORMATION PROCESSING AND CONTROL (BIOLOGICAL)
FEEDBACK CONTROL (NEURAL)
SEE INFORMATION PROCESSING AND CONTROL (NEURAL)
FEEDING (EATING) BEHAVIOR
SEE NUTRIENT INTAKE ACTIVITY. FEEDING (EATING)
BEHAVIOR
FEEDING METHODS (SCHEDULE AND ROUTE)
SEE NUTRITION. DIET SCHEDULE AND ROUTE
FEELINGS
SEE PSYCHOLOGY, EMOTIONS
FELOSAN
SEE PYRIOINAMIDES. NICOTINAMIDE. N-METHYL-
FEMALE
SEE Sa. FEMALE
FEMORAL ARTERY
SEE CARDIOVASCUUR SYSTEM. ARTERIES, FEMORAL ARTERY
FEMORAL HEAD
SI I SKilllAI SYSICM. HIP. KMORAl IKAO
FENTANYL
SEI PIPERIOINLS. KNIANYL
FERNS
Sff PtANIS. IfRNS*
FEROXAMINE
Sn IRON. IIROXAMINI DFKRUXAMINE
FERREDOXIN
Sff MflAllOPROIflNS, fFRREOOXIN
FERRICYANIDE REDUCTASE
Sff OXIOORfOUCTASES. D UCTAIE DEHYDROGENASE
FERRIHEME
SEE HEME. fERRIHEME
FERRIHEMOCHROMES
SEE HEMOCHROMES. FERRIHEMOCHROMES
FERRIHEMOPROTEIN P450 REDUCTASE
SEE OXIDOREDUCTASES. NA0PH2 CYTOCHROME C
REDUCTASE
FERRITIN
SEE METALLOPROTEINS, FERRITIN
FERROXIDASE
SEE METALLOPROTEINS, CERULOPUSMIN
FERTILITY
SEE ALSO FAMILY PLANNING
P50HL14141 05 0007 SCOR for atherosclerosis in
childhood Relation of lipid valves to sexual maturation at
puberty (human)
FERTILITY, ANTIFERTILITY DRUGS
ROlHL-01803 23 0011 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Immunopathologic consequences of
cigarette smoking (human, rabbits, plants)
ROIHL 1255709 Effects of steroids and pregnancy on
arteries and veins (guinea pigs)
ROlHL'13595-08 Renin and vascular hyper-reactivity in
hypertension (human, rats)
** ROlHL-14526-07 Oral contraceptives and hypertension
(rats)
ROlHL-14944-07 Renal vascular reactivity m hypertensive
patient
P60HL-1515807 0011 Comprehensive sickle cell center -
Clinical services-Adult patients
ROlHL-15808-06 Role of angiotensinogen in hypertension
and stroke (human, rabbits)
POlHL-16387-04 0002 The blood vessel and
thrombogenesis - Hormonal effects on thrombogenesis
(rats, rabbits)
*• ROlHL-17366-05 Mechanisms in the production of renal
hypertension (rabbits, dogs)
ROlHL-17721-04 Effect of sex hormones on vascular
connective tissue (rats)
** ROlHL-17724-03 Oral contraceptives and hypertension
(rats)
ROlHL-18333-05 Thrombogenesis and hemostatic balance
(rabbits, human)
POlHL-18574-03 Lipoprotein methodology and biomedical
applications
POlHL-18574-03 0001 Lipoprotein methodology and
biomedical applications - Ultracentrifugal and
electrophoretic lipoprotein methodology-Applications
POlHL-18576-03 0009 Thrombosis research program
project - Biology of factor VII (human, rabbits, cattle)
** ROlHL-19144-03 Contraceptive steroids and experimental
hypertension (rats)
ROlHL-19255-03 Evaluation of diagnostic clinical
hemorrheology (human)
ROlHL-19858-03 UMMC-Blood pressure precursors and
consequences (human)
ROlHL-22225-01 Hormonal regulation of blood pressure
and blood flow (human, animals)
ROlHL-22506-01 Hemodynamics of the clinical
hypertensions
FERTILITY, ANTIFERTILITY DRUGS, MESTRANOL-
NORETHYNODREL
** ROlHL-14526-07 Oral contraceptives and hypertension
(rats)
ROlHL-19144-03 Contraceptive steroids and experimental
hypertension (rats)
FERTILITY, SEX CYCLES, MENSTRUATION
POlHL-14388-07 0232 Regulation of the circulation in
pathological states - Idiopathic cyclic edema
P60HL-15996-06 0005 Cincinnati comprehensive sickle
cell center - Factors precipitating crises (human)
FERTILITY, SPERM (ALL STAGES)
POlHL-08214-15 0025 Chemical and biological properties
of lipids - Biosynthesis and biological functions of
plasmalogen (cattle)
FERTILIZED EGG (MAMMALIAN) TRANSFER
SEE PREGNANCY. EMBRYO-FETUS TRANSPUNTATION
'Excludes routine methodokigy OR covers only general projects which preclude indexing at the specific level.
••Onented significantly to atwve subiect.
FETAL CELL LINES
Ml ll'.'.lil Kill) r.lll IliMI IMIIMrONK. 11 lAI (.III IINf.
FETAL CHEMOTHERAPY
Ml I'MM.NANi.y IMHRVOII MJ', (.MIMIJIHIRAHT
FETAL DEATH
Ml I'MM.NANCY lO'.S IIIAI DIAtll
FETAL DIAGNOSIS
S(l PRf(,NAN(.Y. ANItPARIUM DIAGNOSIS
FETAL DISORDERS
SEE PREGNANCY DISOROfRS. EMBRYO fflAI OI'.ORDfRS
(GENERAL)
FETAL ENZYMES
SEE EN/YMES. FETAt EN/YMES
FETAL FAILURE TO THRIVE
SEE PREGNANCY DISORDERS. EMBRYO FETAL GROWTH
OEVELOPMENI DISORDERS (SEE ALSO APPROPRIATE
SPECIFICS)
FETAL GROWTH DISORDERS
SEE PREGNANCY DISORDERS, EMBRYO FETAL GROWTH
DEVELOPMENT DISORDERS (SEE ALSO APPROPRIATE
SPECIFICS)
FETAL HEMOGLOBIN
SEE HEMOPROTEINS. HEMOGLOBIN FETAL
FETAL HYPOXIA
SEE RESPIRATORY GAS LEVELS. HYPOXIA FETAL
FETAL NUTRITION
SEE NUTRITION. MATERNAL-FETAL NUTRITION
FETAL STRESS
SEE PREGNANCY. PRENATAL STRESS
FETAL SURGERY
SEE PREGNANCY. EMBRYO-FETUS SURGERY
FETAL TRANSPLANTATION
SEE PREGNANCY. EMBRYO-FETUS TRANSPUNTATION
FETUS
SEE PREGNANCY. EMBRYO-FETUS
FETUS TRANSFER
SEE PREGNANCY, EMBRYO-FETUS TRANSPLANTATION
FEVER
SEE TEMPERATURE (BODY), FEVER
FFA
SEE FATTY ACIDS, FREE FATTY ACIDS
FIBER OPTICS
SEE OPTICS, FIBER OPTICS*
FIBRILLATION ATRIAL
SEE HEART DISORDERS, ARRHYTHMIA, ATRIAL FIBRILLATION
FIBRILLATION VENTRICULAR
SEE HEART DISORDERS, ARRHYTHMIA. VENTRICULAR
FIBRILLATION
FIBRIN
SEE BLOOD COAGULATION. FIBRIN
FIBRIN STABILIZING FACTOR
SEE BLOOD COAGULATION, FIBRIN STABILIZING FACTOR
FIBRINASE
SEE BLOOD COAGULATION. FIBRIN STABIUZING FACTOR
SEE BLOOD COAGULATION. PLASMIN
FIBRINOGEN
SEE BLOOD COAGULATION, FIBRINOGEN
FIBRINOGENASE
SEE BLOOD COAGULATION, THROMBIN
FIBRINOLYSIN
SEE BLOOD COAGULATION, PUSMIN
FIBRINOLYTIC AGENTS
SEE BLOOD COAGULATION, FIBRINOLYTIC AGENTS
FIBRINOLYSIN INHIBITORS
SEE BLOOD COAGULATION, ANTIFIBRINOLYTIC AGENTS
FIBRINOLYSIS
SEE BLOOD COAGUUTION, FIBRINOLYSIS
FIBRINOLYSOKINASE
SEE BLOOD COAGUUTION. LYSOKINASE
FIBROBLASTS
SEE CONNECTIVE TISSUE CELLS. FIBROBUSTS
FIBROELASTOSIS, ENDOCARDIAL
SEE HEART DISORDERS. ENDOCARDIAL FIBROEUSTOSIS
FIBROGENESIS
SEE CONNECTIVE TISSUE DEVELOPMENT. FIBROGENESIS
FIBROSING AGENTS
SEE DISEASES, PATHOLOGIC PROCESSES. IRRITATION.
FIBROSING AGENTS
(contd)
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
'^^^jQ^Vi^wuJnAifw '
FIB
214
FRE
FIBROSIS
SEE HEART DISORDERS. CORONARY FIBROSIS
SEE HEART DISORDERS. ENDOMYOCARDIAL FIBROSIS
SEE METABOLIC DISORDERS INBORN, CYSTIC FIBROSIS
SEE RESPIRATORY DISORDERS. PULMONARY FIBROSIS AND
GRANULOMAS
FIBROUS DIETS
SEE NUTRITION. DIETARY CONSTITUENTS. DIETARY RESIDUES-
FIBERS
FIBROUS PROTEINS
SEE ALSO ALBUMINOIDS. COLUGEN
SEE ALSO ALBUMINOIDS. ELASTIN
R01HL0889314 Structure and function of membrane
proteins (human)
POlHL'l 1310-12 0101 Mechanisms of cardiovascular
disease - Molecular pathogenesis of vascular disease
P60HL 16005-05 0015 Comprehensive sickle cell center -
Molecular basis for the sickling phenomenon
ROIHL 23233 01 Pulmonary artery intermediate filament
structure (cattle)
** NOIHR 62910-02 Fibroprotein networks of pulmonary
alveolar wall (human)
FICK METHOD
SEE HEART DISORDERS DIAGNOSIS. FICK METHOD*
FILIPIN
SEE ANTIBIOTICS. FILIPIN
FILMS
SEE MOLECUUR FILMS
FILTERS AND FILTRATION
SEE BLOOD TREATMENT. BLOOD FILTERS
SEE PHYSICAL SEPARATION. MOLECULAR SIEVES*
FINANCING ORGANIZED
SEE SOCIOECONOMICS. FINANCING ORGANIZED
FINGERS
SEE SKELETAL SYSTEM. LIMB. FINGERS
FISH*
** ROlHL-15460-06 Molecular adaptation -Hemoglobin
systems of fish (marine)
** R01HL-19164-03 Piscine erythrocytic necrosis in the
Atlantic cod
FISTULA
SEE CARDIOVASCUUR DISORDERS. ARTERIOVENOUS SHUNTS
ABNORMAL
FIXED ACTION PATTERN (ANIMAL BEHAVIOR)
SEE PSYCHOLOGY. BEHAVIOR ANIMAL
FIXED CHARGE HYPOTHESIS
SEE BIOLOGICAL TRANSPORT. PASSIVE TRANSPORT.
DIFFUSION
FIXED CHARGES IN TRANSPORT ENERGETICS
SEE BIOLOGICAL TRANSPORT. TRANSPORT ENERGETICS
FIXING OF TISSUES OR CELLS
SEE TISSUE AND CELL PREPARATION
FLAGELLA
SEE CELL COMPONENTS. FLAGELLA
FLAVIN ADENINE DINUCLEOTIDE
SEE FLAVIN NUCLEOTIDES. RIBOFLAVIN NUCLEOTIDES. FAD
FLAVIN NUCLEOSIDES, RIBOFLAVIN
P01HL-16251-06 0003 Membrane-bound enzymes in heart
and other tissues - Regulation of cardiac succinate
dehydrogenase (yeasts, mammals)
FLAVIN NUCLEOTIDES, RIBOFLAVIN
NUCLEOTIDES, FAD
P01HL-07896-15 0032 Environmental biomedical research
program - Fluorometry study of brain exposed to hyperbaric
oxygen (dogs, cats)
R01HL-13028-09 Regulation of myocardial fatty acid
metabolism (rats)
POlHL-16251-06 0010 Membrane-bound enzymes in hear*
and other tissues - Reversible activation of L-amino acid
oxidase (snakes)
ROlHL-19279-03 Intracellular action of aldosterone in
hypertension (human, rats)
FLAVINS
SEE ALSO FLAVOPROTEIN ENZYMES
** POlHL-16251-06 0001 Membrane bound enzymes in heart
and other tissues - Structure of covalently bound flavins
(bacteria, yeast, mammals)
POlHL-16251-06 0002 Membrane-bound enzymes in heart
and other tissues - Structural basis of regulation of
cardiac succinate dehydrogenase
** P01HL16251-06 0004 Membrane-bound enzymes in heart
and other tissues - Biosynthesis and degradation of
succinate dehydrogenase, histidyl (yeast, mammal)
•* POlHL-16251-06 0007 Membrane-bound enzymes in heart
and other tissues - Flavins and flavoproteins
FLAVODOXIN
ROlHL-19481 03 High-field NMR studies of respiratory
proteins (human, horse, fish, microbes)
FLAVONOIDS
POlHL-07896-15 0049 Environmental biomedical research
program - Effects of hyperbaric oxygen and pressure on
cerebral enzymes (rats)
FLAVOPROTEIN ENZYMES
ROlHL-136 19-09 Microsomal electron transport in liver
and heart (human, mammals)
P01HL-15835-06 0013 Study of muscles related to heart
disease - Cardiac bioenergetics (rats)
** POlHL-16251-06 0007 Membrane-bound enzymes in heart
and other tissues - Flavins and flavoproteins
ROlHL-18089-04 Fatty acid metabolism in heart and its
regulation (swine, rats)
FLOWMETERS, AIRFLOWMETERS (RESPIRATORY)
SEE RESPIRATORY DISORDERS DIAGNOSIS, RESPIRATORY
AIRFLOW MEASUREMENTS*
FLOWMETERS, BLOOD
SEE CARDIOVASCUUR DISORDERS DIAGNOSIS, BLOOD FLOW
MEASUREMENTS*
FLUDROCORTISONE
SEE ADRENAL CORTEX HORMONES ANALOGS,
FLUDROCORTISONE
FLUID DYNAMICS
SEE PHYSICAL PROPERTIES, FLUID DYNAMICS (GENERAL)
FLUID-ELECTROLYTE BALANCE
SEE BODY FLUID BALANCE, IONIC
FLUID EXCHANGE AND TRANSPORT
SEE BIOLOGICAL TRANSPORT, FLUID EXCHANGE AND
TRANSPORT
FLUID FLOW
SEE PHYSICAL PROPERTIES, FLUID FLOW
FLUID FLOW IMPEDANCE
SEE PHYSICAL PROPERTIES. FLUID FLOW IMPEDANCE
FLUID STATE
SEE PHYSICAL PROPERTIES. FLUID STATE
FLUIDS
SEE BODY FLUIDS (AND RELATED SUBSTANCES)
SEE CELL FLUIDS
SEE PHYSICAL PROPERTIES, FLUID STATE
FLUORESCEINS
SEE BENZOPYRANS, XANTHENES, FLUORESCEINS
FLUORESCENCE
SEE OPTICS, LIGHT EMISSION, FLUORESCENCE*
FLUORESCENCE LABELING, PROBES
SEE DYES, FLUORESCENT DYES AND PROBES
FLUORESCENCE MICROSCOPY
SEE OPTICS, MICROSCOPY, FLUORESCENCE*
FLUORESCENCE SPECTROMETRY
SEE CHEMISTRY, ANALYTICAL METHODS, SPECTROMETRY.
FLUORESCENCE*
FLUORESCENT ANTIBODY TECHNIQUE
SEE IMMUNOLOGICAL TESTS AND IMMUNOASSAY,
IMMUNOFLUORESCENCE*
FLUORESCENT ANTIGEN TECHNIQUE
SEE IMMUNOLOGICAL TESTS AND IMMUNOASSAY,
IMMUNOFLUORESCENCE*
FLUORESCENT DYES
SEE DYES, FLUORESCENT DYES AND PROBES
FLUORIDES
SEE HALOGENS, FLUORINE (COMPOUNDS) SEE ALSO
SPECIFICS
FLUORINE (COMPOUNDS)
SEE HALOGENS, FLUORINE (COMPOUNDS) SEE ALSO
SPECIFICS
FLUORINE RADIOISOTOPES (18)
SEE RADIOISOTOPES, FLUORINE
FLUOROCARBON ASSIST
SEE RESPIRATORY ASSIST AND OXYGEN ADMINISTRATION,
FLUOROCARBON
FLUOROCARBON POLYMERS
SEE PLASTICS, FLUOROCARBON POLYMERS
FLUOROCINEMATOGRAPHY
SEE RADIOGRAPHY, CINEFLUOROGRAPHY*
9ALPHA-FLUOROHYDROCORTISONE
SEE ADRENAL CORTEX HORMONES ANALOGS,
FLUDROCORTISONE
FLUOROMETRY
SEE OPTICS. FLUOROMETRY*
FLUOROSCOPY
SEE RADIOGRAPHY, FLUOROSCOPY*
FLURAZEPAM
SEE AZEPINES, DIAZEPINES. FLURAZEPAM
FNS (FUNCTIONAL NEUROMUSCULAR
STIMULATORS FOR NEUROMOTOR
DISORDERS)
SEE NEUROMUSCULAR STIMULATORS (FOR NEUROMOTOR
DISORDERS)
FOAMING AGENTS
SEE PHYSICAL PROPERTIES, SURFACTANTS
FOLIC ACID
R01HL-13987-04 Transplantation of the lung (dogs)
P60HL-1 5158-07 0011 Comprehensive sickle cell center -
Clinical services-Adult patients
FOLIC ACID ANTAGONISTS, METHOTREXATE
P01HL-1043e-13 0005 A multidisciplinary study of
congenital heart disease - Pulmonary physiology in
congenital heart disease (human)
ROIHL 13987-04 Transplantation of the lung (dogs)
ROlHL-1552605 Respiratory mechanics in children
FOLLOW-UP STUDY
SEE POPULATION STUDIES HUMAN, LONGITUDINAL STUDY
FOLLOW-UP STUDY, ANIMAL
SEE POPUUTION STUDIES ANIMAL, LONGITUDINAL STUDY
FOOD, ANIMAL FEEDS, SILAGE
P50HL- 15389-07 0009 Pulmonary SCOR-Hypersensitivity
pneumonitis - Clinical studies-Pulmonary mycotoxicosis
P50HL-15389-07 0013 Pulmonary SCOR-Hypersensitivity
pneumonitis - Animal model -Pulmonary mycotoxicosis
(rabbit, guinea pig)
FOOD, BEVERAGES, COFFEE
** P50HL 15092-07 0011 Immune and fibrotic response to
occupational environments - Respiratory and immunologic
responses in coffee plant workers
P50HL- 15092-07 0014 Immune and fibrotic response to
occupational environments - Clinical immunology core
resource
ROlHL-19839-09 Factors in youth predisposing to chronic
diseases (former college students)
FOOD, MEAT SUBSTITUTES
ROlHL-20910-02 The alternative diet for coronary disease
prevention (human)
FOOD ADDITIVES
SEE FOOD SCIENCES AND TECHNOLOGY, FOOD ADDITIVES
FOOD ANALYSIS (CHEMICAL CONSTITUENTS)
SEE NUTRITION, DIETARY CONSTITUENTS (GENERAL)
FOOD CONSTITUENTS
SEE NUTRITION, DIETARY CONSTITUENTS (GENERAL)
FOOD REQUIREMENTS DIETARY
SEE NUTRITIONAL REQUIREMENTS
FOOD SCIENCES AND TECHNOLOGY, FOOD
ADDITIVES
SEE ALSO OXIDANTS, ANTIOXIDANTS
R01HL15980-06 Reactions of hemeproteins and oxygen
(cattle)
FORAMEN OVALE (HEART) EMBRYONIC
SEE HEART, FORAMEN OVALE EMBRYONIC
FORAMEN OVALE (HEART) PATENT
SEE CONGENITAL ABNORMALITIES, HEART SEPTAL DEFECTS
FORANE
SEE HALOETHERS, FORANE
FOREBRAIN
SEE BRAIN, PROSENCEPHALON (GENERAL)
FOREIGN BODY (REACTION)
SEE DISEASES, PATHOLOGIC PROCESSES, INFLAMMATION,
FOREIGN BODY (REACTION)
FORMALDEHYDE
SEE ALDEHYDES. FORMALDEHYDE
FOURIER TRANSFORM SPECTROSCOPY
SEE OPTICS. INTERFEROMETRY*
FRACTIONATION (GENERAL)
SEE PHYSICAL SEPARATION. FRACTIONATION (GENERAL)*
FRAMESHIFT
SEE GENETICS. MUTATION. GENE MUTATION. FRAMESHIH
FREE FATTY ACIDS
SEE FATTY ACIDS, FREE FATTY ACIDS
FREE RADICALS
SEE ELECTRONIC SPECTRA. FREE RADICALS
FREEZE-ETCHING
SEE TEMPERATURE. FREEZE-ETCHING*
FREEZING
SEE TEMPERATURE, FREEZING
(contd)
*Excludes routine methodology OR covers only general projects which precli'de indexing at the specific level.
**OrierTted significafltiy to above subject.
M Grant has subprojeds describing specific research aspects.
See Appendix for investigator's name and grant number.
FRf
PRtSH-WATCR OROANISMS
Sff WMfR fNVIRONMiNI AQUAIIC ORGANISMS, FRESH
WATER-
NIEUND'S ADJUVANT
Sff IMMtlNOlOGICAl PRtPARAIIONS. AOIUVANIS
IMMUNOLOGIC. IREUNO S AOIUVANI
FRICTIONAL PROPERTIES
SEE MOLECULAR FRICIIONAL PROPERTIES
FROGS AND TOADS
SEE AMPHIBIANS. ANURANS*
FRONTAL LOBE
SEE BRAIN, CEREBRUM, FRONTAL LOBE
FRUCTOSE
SEE HEXOSES. FRUCTOSE
FRUCTOSE 1 ,6-DIPHOSPHATASE
SEE PHOSPHOMONOESTERASES, FRUCTOSE 1,6-
OIPHOSPHAlASE
FSF
SEE BLOOD COAGUUTION, FIBRIN STABILIZING FACTOR
FUNCTIONAL GROUPS (CHEMISTRY)
SEE CHEMICAL REACTION SITES. FUNCTIONAL GROUPS
FUNCTIONAL NEUROMUSCULAR STIMULATORS
(FOR NEUROMOTOR DISORDERS)
SEE NEUROMUSCULAR STIMULATORS (FOR NEUROMOTOR
DISORDERS)
FUND RAISING
SEE HEALTH ECONOMICS, FUND RAISING
FUNGAL ANTIBODIES
SEE IMMUNOLOGY, ANTIBODIES FUNGAL
FUNGAL ANTIGENS
SEE IMMUNOLOGY. ANTIGENS FUNGAL
FUNGI*
SEE ALSO BACTERIOLOGY AND MYCOLOGY STUDY SECTION
SEE ALSO TOXICOLOGY, MYCOTOXINS
P01HL082M 15 0048 Chemical and biological properties
of lipids • Lipids in microorganisms and plants
P50HL-1538907 0019 Pulmonary SCOR-Hypersensitiwlty
pneumonitis ■ Microbiology core (human, animal)
FUNGICIDES
SEE COMMUNICABLE DISEASE CONTROL AGENTS
ANTIFUNGAL
FURANS
SEE OXOLES, FURANS
FURO(BETA)MONAZOLE
SEE OXAZOLES
FURSEMIDE
SEE SULFANIUMIDES, FURSEMIDE
GAGGING REFLEX
SEE RESPIRATORY SYSTEM REFLEXES
GALACTANS
SEE HEXOSANS, GAUCTAN
GALACTOSAMINES
SEE HEXOSES, GALACTOSAMINES
BETA-GALACTOS IDASE
SEE CARBOHYDRASES, BETA-GAUCTOSIDASE
GALACTOSYLTRANSFERASES
SEE GLYCOSYLTRANSFERASES. GAUCTOSYLTRANSFERASES
GAUBLADDER DISORDERS
SEE BILIARY TRACT DISORDERS, GALLBLADDER DISORDERS
GALUUM RADIOISOTOPES (67,68)
SEE RADIOISOTOPES, GALLIUM
GALLSTONES
SEE BILIARY TRACT DISORDERS. CHOLEUTHS
GAMAAA GLOBUUNS
SEE GLOBULINS. GAMMA GLOBULINS
GAMA«A GLOBULINS 7S
SEE GLOBUUNS, GAMMA GLOBULINS. IMMUNOGLOBULIN G
GAMAAA GLOBULINS I9S
SEE GLOBULINS. GAMMA GLOBULINS. IMMUNOGLOBULIN M
GAMMA RAY SCANNING
SEE RADIOAUTOGRAPHY. RADIONUCLIDE SCANNING*
GANGLIA NERVOUS SYSTEM
SEE NERVOUS SYSTEM. GANGLIA
GANGUONIC BLOCKING AGENTS
SEE NEUROPHARMACOLOGICAL AGENTS. GANGLIONIC
BLOCKING AGENTS
GANGUONIC STIMULATING AGENTS
SEE NEUROPHARMACOLOGICAL AGENTS. GANGLIONIC
STIMULATING AGENTS
lis
GANGRENE (GENERAL)
Sll DISIASIS. PAIHOIOC.IC PROCESSES, NECROSIS
GANCRfNI ir.fNIRAl)
GARLIC AND ONION
Sll PIANIS. ANGIOSPfRMS. AUIUM*
GAS ANALYZERS, RESPIRATORY GASES
Sff RfSPIRAIORY GAS ANAIY/ERS*
GAS CHROMATOGRAPHY
SEE PHYSICAl SEPARATION, CHROMATOGRAPHY, GAS*
GAS ELEMENTS, HEUUM
P01H107896 IS 0029 Environmental biomedical research
program Oxygen helium diving resulting in high pressure
nervous syndrome (human, animals)
POIHL 08899 14 0064 Tolerance to respiratory gases in
health and disease Narcotic effects of inert gases on
functional systems (rats)
POIHL 08899 14 0073 Tolerance to respiratory gases In
health and disease Biophysical mechanisms involved in
isobaric gas counterdiffusion syndrome
POIHL 1441407 0004 Environmental influences on
cardiorespiratory and cellular functions Role of diffusion
in gas exchange (chichen egg)
ROIHL 2240601 Isobaric vascular bubbles and
decompression sickness (goats, models)
GAS ELEMENTS, INERT
** POIHL 07896 15 0008 Environmental biomedical research
program Otologic studies under hyperbaric conditions
(human, animals)
P01HL0789615 0009 Environmental biomedical research
program ■ Decompression sickness and computation of safe
diving tables (human, animals)
P01HL0789615 0014 Environmental biomedical research
program - Mechanisms of respiration and circulation
(human, dogs)
POlHL-07896-15 0050 Environmental biomedical research
program ■ Fundamental decompression concepts using the
rat animal model
M POlHL-0889914 Tolerance to respiratory gases in health
and disease
Tolerance to respiratory gases in
Inert gas exchange in the eye
P01HL0889914 0003
health and disease -
(human, dogs)
POlHL-08899-14 0006
health and disease
*&clu(tes routine methodotogy OR covers only general projects which preclude indexing at the specific level
Onenleo significantly to above subject.
Tolerance to respiratory gases in
Effects of extreme pressures of inert
gases in macaque monkey
POlHL-08899-14 0018 Tolerance to respiratory gases in
health and disease - Effects of respiratory gases at
extreme pressures (human)
** P01HL08899-14 0022 Tolerance to respiratory gases in
health and disease - Effect of inert gas and hydrostatic
pressures on physiological functions (monkey)
*• POlHL-08899-14 0028 Tolerance to respiratory gases in
health and disease ■ Inert gas exchange, oxygen influences-
organs and tissues (human, rabbits, dogs)
** P01HL0889914 0029 Tolerance to respiratory gases in
health and disease - Isobaric gas counter diffusion
phenomena (human, pigs)
P01HL08899-14 0073 Tolerance to respiratory gases in
health and disease - Biophysical mechanisms involved in
isobaric gas counterdiffusion syndrome
POIHL-0889914 0076 Tolerance to respiratory gases in
health and disease - Bubble formation during gas
counterdiffusion (hamsters)
** P01HL0889914 0077 Tolerance to respiratory gases in
health and disease - Isobaric gas supersaturation patterns
P01HL08899-14 0079 Tolerance to respiratory gases in
health and disease - Physiological factors in
counterdiffusion bubble formation (human, pigs)
POlHL-08899-14 0089 Tolerance to respiratory gases in
health and disease • Decompression by applications of
optimal control theory
POlHL-121 57-11 0038 Functions and mechanisms of cell
membrane ion transport ■ Mechanisms and interactions of
gases and ions with bilayer membranes (human)
ROlHL-12879-09 0007 Pulmonaiy transport and
metabolism in vivo - Effects of temperature changes on
pulmonary transport
POlHL-144 14-07 0004 Environmental influences on
cardiorespiratory and cellular functions • Role of diffusion
in gas exchange (chicken egg)
POIHL-144 14-07 0010 Environmental influences on
cardiorespiratory and cellular functions • Pressure effects
on cardiac electrical phenomena (animals)
M POlHL-1 51 94-07 Pathophysiology of cardiopulmonary
dysfunction
POlHL-15194-07 0023 Pathophysiology of
cardiopulmonary dysfunction - Distribution of ventilation-
Diffusion and cardiogenic agitation (dogs)
POlHL-1 51 94-07 0024 Pathophysiology of
cardiopulmonary dysfunction - Distribution of ventilation-
Airflow limitation in COLD (human)
ROlHL-19449-03 Gas exchange in acute respiratory failure
GAS ELEMENTS, NEON
POlHL-08899-14 0064 Tolerance to respiratory gases in
health and disease - Narcotic effects of inert gases on
functional systems (rats)
ROlHL-22406-01 Isobaric vascular bubbles and
decompression sickness (goats, models)
M Grant has subprajects describing specific research aspects
See Appendix for invest igators name and grant number
OAt
GAS ELEMENTS, OZONE
I'UIIII Q<i^8-j \H OIHH f.aidioviuulii ((ipiritory
physiology and biochemiilry Phyiiology ind ph«imtcolo|y
in legulation of airwiyi hyptiiiiitabihty (aninialil
POIHL 063/0 1/ 0006 Cardiopulmonary and renal
pathology research center Chemical batii of
ultiatlructuial changes in diseiM (ratt)
PSOHL 15061 0/ 0012 Response of lung to injury
Hyperbaric oxygen, carbon monoxide, and o/one or paioiidt
toxicity (rats)
ROIHL 16029 05 Bio organic chemistry of o<one, nitrogan
dioxide and tobacco smoke
ROIHL 18918 03 Characteiuatmn of lung elastins (rat,
rabbit, chicken. Rhesus)
** P50HL 19156 02 0001 Pulmonary SCOR Chronic diseases
of airways Irritability of airways induced by epithelial
damage in healthy subjects (human)
P50HL 1915602 0005 Pulmonary SCOR Chronic diseases
of airways Vagal receptors in the airway Epithelial injury
and antigen (dog, cat. rabbit)
ROIHL 1966803 Biochemistry of lung connective tissue
(rats)
ROIHL 1972003 Evaluation of anti fibrotic agents in
pulmonary fibrosis (rats)
ROIHL 2100902 EHects of air pollutants on lung cells in
culture (rats)
GAS ELEMENTS, XENON
SEE ALSO RADIOISOTOPES. XENON
ROIHL 20761 02 Study of cerebral blood flow with stable
xenon and computerized tomography
GAS TENSIONS, RESPIRATORY GASES
SEE RESPIRATORY GAS LEVELS
GAS TRANSPORT, HYDROGEN
SEE CHEMICAL TRANSFER. HYDROGEN TRANSPORT
GAS TRANSPORT RESPIRATORY
SEE RESPIRATORY GAS TRANSPORT
GASES (GENERAL)
POlHL-07896-15 0045 Environmental biomedical research
program - Extravascular lung water dynamics in pulmonary
oxygen toxicity (human, baboons)
** POlHL-12157-11 0038 Functions and mechanisms of cell
membrane ion transport • Mechanisms and interactions of
gases and ions with bilayer membranes (human)
ROlHL-13651-07 X-ray photoelectron spectroscopy of heme
compounds
POlHL-16137-05 0008 Alveolar biology Macromolecular
events in pulmonary cells in toxic environments (animals)
ROlHL-2 1120-02 Membrane dynamics in alveolar
macrophages (rabbits)
GASES, RESPIRATORY
SEE RESPIRATORY GASES
GASTRIC ACID
SEE GASTROINTESTINAL SYSTEM. STOMACH, GASTRIC JUICE
GASTRIC ACID
GASTRIC JUICE
SEE GASTROINTESTINAL SYSTEM. STOMACH. GASTRIC JUICE
GASTRIC JUICE INHIBITORS
SEE GASTROINTESTINAL SYSTEM. STOMACH. GASTRIC JUICE
INHIBITORS
GASTRIN
SEE GASTROINTESTINAL HORMONES. GASTRIN
GASTROINTESTINAL ABSORPTION-TRANSPORT
SEE GASTROINTESTINAL FUNCTION, ABSORPTION-TRANSPORT
(GENERAL)
GASTROINTESTINAL AGENTS, LAXATIVES
P01HL-20993-02 0004 Population dynamics of arterial
cells in atherogenesis - Modifications of cholesterol balance
related to arterial cell divisions (swine)
GASTROINTESTINAL CIRCULATION
SEE ALSO LIVER CIRCULATION
ROlHL-00487-29 Vasomotor tone and venous return
(human, dogs, monkeys )
ROlHL-03181-21 0028 Hemodynamics as applied to
surgical problems - Extra-renal factors in the hypertension
of coarctation (dog)
POlHL-1 1678-11 0039 Cardiovascular dynamics and their
control - Capillary and interstitial fluid dynamics of the
intestine (cats)
R01HL11901-12 0015 Effects of metabolic surgery on
the hyperlipidemias - Portacaval shunt for cholesterol
reduction (dogs, rabbits)
ROIHL- 1334 1-06 Lymph-An indication of splanchnic tissue
respiration (dogs, human, rats)
ROlHL-15231-05 Mechanisms of hemodynamic changes
during digestion (dogs)
ROlHL-15607-06 Physiological control of splanchnic
circulation (dogs)
R01HL-16315-05 Analysis of interaction between CNS
vasomotor systems (cats, rats)
ROlHL-17091-05 Anesthetics and microvascular response
to hemorrhage (rats)
** ROlHL-17954-03 Narcotics and the circulation (human.
dogs. pigs, monkeys)
(contd)
GAS
** R01HL-lg020-04 Splanchnic hemodynamics in man
• ** ROlHL-18080-03 Extrinsic control of intestinal
microcirculation (dogs)
** ROlHL-18096-04 Vasoactive agents in splanchnic viscera
(primates, dogs)
R01HL18994-03 Substance P-Occurrence. pharmacology
and physiology (mammals non-human, human)
** ROlHL-19997-02 Prostaglandin precursors and intestinal
vasculature (cats, rabbits)
" ROlHL-20371-02 Intravascular redistribution of blood
volume (dogs)
** ROlHL-20572-02 0003 Hemodynamic relations to
metabolism in hypertension ■ Cardiac output and organ
blood flow in hypertension (rats)
ROlHL-20685-02 Pituitary-adrenergic-ovarian vasomotor
interaction (dogs)
ROlHL-20766-02 Control of circulation in heat stress
(baboons)
*♦ ROlHL-20864-01 Postnatal maturation of cardiovascular
regulatory system (minipig)
** ROlHL-2 1308-01 Prostaglandins and local control of the
circulation (rats, dogs)
** ROlHL-21351-02 Renal and vascular control by
sympathetic ganglia (animals)
** ROlHL-22506-01 Hemodynamics of the clinical
hypertensions
ROlHL-2331201 Hemodynamics and vasoactivity in renal
hypertension (human, dogs)
GASTROINTESTINAL CIRCULATORY DISORDERS
SEE ALSO LIVER CIRCULATORY DISORDERS
ROlHL-13341-06 Lymph-An indication of splanchnic tissue
respiration (dogs, human, rats)
GASTROINTESTINAL CIRCULATORY DISORDERS,
CIRCULATORY INSUFFICIENCY
** ROlHL-03181-21 0027 Hemodynamics as applied to
surgical problems ■ Hemodynamic studies of the 61 tract
(dogs)
ROlHL-1523105 Mechanisms of hemodynamic changes
during digestion (dogs)
ROlHL-1808003 Extrinsic control of intestinal
microcirculation (dogs)
ROlHL-1809604 Vasoactive agents in splanchnic viscera
(primates, dogs)
GASTROINTESTINAL CIRCULATORY DISORDERS,
ESOPHAGEAL VARICES
ROlHL-18020-04 Splanchnic hemodynamics in man
GASTROINTESTINAL CIRCULATORY DISORDERS,
HEMORRHAGE, GASTROINTESTINAL
ROlHL-1809604 Vasoactive agents in splanchnic viscera
(primates, dogs)
GASTROINTESTINAL CIRCULATORY
INSUFFICIENCY
SEE GASTROINTESTINAL CIRCULATORY DISORDERS,
CIRCULATORY INSUFFICIENCY
GASTROINTESTINAL DISORDERS
SEE ALSO GASTROINTESTINAL CIRCUUTORY DISORDERS
SEE ALSO LIVER DISORDERS
R01HL18994-03 Substance P -Occurrence, pharmacology
and physiology (mammals non-human, human)
GASTROINTESTINAL DISORDERS, DIVERTICULITIS
ROlHL-19839-09 Factors in youth predisposing to chronic
diseases (former college students)
GASTROINTESTINAL DISORDERS, DUODENAL,
DUODENAL ULCER
m POlHL-06370-17 Cardiopulmonary and renal pathology
research center
** POlHL-06370-17 0015 Cardiopulmonary and renal
pathology research center - Pathogenesis of chemically
induced tissue injury (rats)
ROlHL-19839-09 Factors in youth predisposing to chronic
diseases (former college students)
GASTROINTESTINAL DISORDERS, EMESIS
SEE ALSO GASTROINTESTINAL SIGNS-SYMPTOMS, NAUSEA
ROlHL-2111701 Altitude adaptation in chronic lung
disease (human)
GASTROINTESTINAL DISORDERS, ENTERITIS,
ULCERATIVE COLITIS
R01HL1983909 Factors in youth predisposing to chronic
diseases (former college students)
GASTROINTESTINAL DISORDERS, INTESTINAL
DISORDERS (GENERAL)
ROlHL-15231-05 Mechanisms of hemodynamic changes
during digestion (dogs)
GASTROINTESTINAL DISORDERS,
MALABSORPTION SYNDROMES
SEE ALSO GASTROINTESTINAL FUNCTION, ABSORPTION-
TRANSPORT (GENERAL)
SEE ALSO METABOLIC DISORDERS INBORN, CYSTIC FIBROSIS
SEE ALSO METABOLIC DISORDERS INBORN, DISACCHARIDE
(OLIGOSACCHARIDE) INTOLERANCE
SEE ALSO METABOLIC DISORDERS INBORN,
HYPOLIPOPROTEINEMIAS FAMILIAL,
ABETALIPOPROTEINEMIA
216
** R01HL17332-04 Use of the gut for therapy of coronary
artery disease (mammals)
GASTROINTESTINAL DISORDERS, PEPTIC ULCER
SEE ALSO GASTROINTESTINAL DISORDERS, DUODENAL,
DUODENAL ULCER
ROIHL- 198 39-09 Factors in youth predisposing to chronic
diseases (former college students)
ROlHL-22258-01 Nev» aspects of pharmacology related to
carbonic anhydrase
GASTROINTESTINAL DISORDERS
CHEMOTHERAPY
SEE ALSO BILIARY TRACT DISORDERS CHEMOTHERAPY
SEE ALSO GASTROINTESTINAL FUNCTION, ABSORPTION-
TRANSPORT, DRUGS
SEE ALSO GASTROINTESTINAL PHARMACOLOGY
SEE ALSO LIVER DISORDERS CHEMOTHERAPY
ROlHL-22258-01 New aspects of pharmacology related to
carbonic anhydrase
GASTROINTESTINAL EXCRETA, FECES
R23HL-2 1083-02 Pharmacokinetics of digoxin and digitoxin
in humans (rats)
GASTROINTESTINAL FUNCTION, ABSORPTION-
TRANSPORT (GENERAL)
SEE ALSO BILE ACIDS AND SALTS, ENTEROHEPATIC
CIRCULATION
SEE ALSO GASTROINTESTINAL DISORDERS, MAUBSORPTION
SYNDROMES
** ROlHL-096 10-14 Control of cholesterol metabolism-Bile
acid transport
ROlHL-10940-13 Lipid transport (rabbits, cattle, chickens)
ROlHL-1 1901-12 0015 Effects of metabolic surgery on
the hyperlipidemias - Portacaval shunt for cholesterol
reduction (dogs, rabbits)
** ROlHL-17332-04 Use of the gut for therapy of coronary
artery disease (mammals)
ROlHL-17818-05 Metabolism of cholesterol and cholesterol
in man (also rats, monkeys)
ROlHL-2256101 Hormonal control of mesenteric
circulation (cats)
** ROlHL-22569-02 Intestinal secretion-Capillary and tissue
forces (dogs, cats)
GASTROINTESTINAL FUNCTION, ABSORPTION-
TRANSPORT, DIETARY NUTRIENTS
ROlHL-06222-18 Clinical and laboratory studies in lipid
metabolism (human, mammals, non-human)
ROlHL-096 10-14 Control of cholesterol metabolism -Bile
acid transport
ROlHL-09744-14 Experimental vascular sclerosis
(monkeys, rabbits)
R01HL-10894-12 Intestinal bacteria and steroid
metabolism (human, guinea pigs, rabbits, rats)
ROlHL-11901-12 0001 Effects of metabolic surgery on
the hyperlipidemias - Partial ileal bypass (human)
** R01HL11901-12 0012 Effects of metabolic surgery on
the hyperlipidemias - Ileal bypass-Animal atherosclerosis
implications (pigeons, dogs, rabbits)
R01HL1190112 0013 Effects of metabolic surgery on
the hyperlipidemias - Human cholesterol and bile acids
dynamics-Heal bypass
ROlHL-11901-12 0019 Effects of metabolic surgery on
the hyperlipidemias - Cholesterol, bileacids, lipoproteins in
obese humans
ROlHL-1239913 Specific fatty acids and cholesterol
metabolism (gerbils, rats)
P50HL-141 97-07 0006 Support for center of research on
arteriosclerosis - Diets and drugs affecting lipid
metabolism (human)
** ROlHL-1523105 Mechanisms of hemodynamic changes
during digestion (dogs)
ROlHL-17332-04 Use of the gut for therapy of coronaiy
artery disease (mammals)
ROlHL-18623-12 Physical chemistry of biologically active
lipids (bacteria, plant, cattle, human)
** R01HL-18636-02 Fatty acids and cholesterol transport
(rats)
** P50HL-19362-02 0009 A/S SCOR -Atherosclerosis in
nonhuman primates - Cholesterol metabolism and
intestinal microflora (baboon)
P50HL-19362-02 0013 A/S SCOR-Atherosclerosis in
nonhuman primates - Core laboratory-Lipid biochemistry
(baboons)
** ROlHL-20605-02 Microvascular responses during intestinal
absorption (rats)
** ROlHL-22567-01 Validation of a cholesterol absorption
method in man
GASTROINTESTINAL FUNCTION, ABSORPTION-
TRANSPORT, DRUGS
ROIHL 18068-02 Chemistry and activity of homologous
heparin fractions (rodents)
ROlHL-19820-02 The chemistry and biological effects of
heparin (Rhesus, human, other mammals)
** ROlHL-21476-02 Anticoagulant drug absorption
interactions (rats)
GASTROINTESTINAL FUNCTION, DEGLUTITION
P50HL-142 14-07 0027 Newborn lung center for hyaline
membrane disease - Oral-laryngeal chemoreceptors and
respiratory failure in newborns (human, sheep)
GAS
GASTROINTESTINAL FUNCTION, DIGESTION
ROlHL-15231-05 Mechanisms of hemodynamic changes
during digestion (dogs)
GASTROINTESTINAL HEMORRHAGE
SEE GASTROINTESTINAL CIRCULATORY DISORDERS,
HEMORRHAGE, GASTROINTESTINAL
GASTROINTESTINAL HORMONES
** P50HL14187-07 0012 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses ■ Vasoactive
mediators in pulmonary disease (human, animal)
ROlHL-15231-05 Mechanisms of hemodynamic changes
during digestion (dogs)
GASTROINTESTINAL HORMONES, GASTRIN
SEE ALSO GASTROINTESTINAL SYSTEM, STOMACH. GASTRIC
JUICE
** ROlHL-11901-12 0014 Effects of metabolic surgery on
the hyperlipidemias ■ Effect of bypass on gastrin levels
(dogs, human)
R01HL11901-12 0019 Effects of metabolic surgery on
the hyperlipidemias - Cholesterol, bileacids, lipoproteins in
obese humans
ROlHL-22561-01 Hormonal control of mesenteric
circulation (cats)
GASTROINTESTINAL HORMONES,
PANCREOZYMIN-CHOLECYSTOKININ
ROlHL-22561-01 Hormonal control of mesenteric
circulation (cats)
GASTROINTESTINAL HORMONES, SECRETIN
ROlHL-2256101 Hormonal control of mesenteric
circulation (cats)
ROlHL-22569-02 Intestinal secretion-Capillary and tissue
forces (dogs, cats)
GASTROINTESTINAL PHARMACOLOGY
SEE ALSO BILIARY TRACT PHARMACOLOGY
SEE ALSO GASTROINTESTINAL DISORDERS CHEMOTHERAPY
ROlHL-17332-04 Use of the gut for therapy of coronary
artery disease (mammals)
ROlHL-17564-03 Unsaturated fats-Mode of
hypocholesterolemic action (minipig)
ROlHL-18080-03 Extrinsic control of intestinal
microcirculation (dogs)
ROlHL-22567-01 Validation of a cholesterol absorption
method in man
GASTROINTESTINAL PRESSURE-MOTILITY
SEE ALSO GASTROINTESTINAL DISORDERS, EMESIS
ROIHL- 18994-03 Substance P-Occurrence, pharmacology
and physiology (mammals non-human, human)
GASTROINTESTINAL SIGNS-SYMPTOMS,
NAUSEA
SEE ALSO GASTROINTESTINAL DISORDERS, EMESIS
ROlHL-21117-01 Altitude adaptation in chronic lung
disease (human)
GASTROINTESTINAL SURGERY
ROlHL-1190112 0015 Effects of metabolic surgery on
the hyperlipidemias - Portacaval shunt for cholesterol
reduction (dogs, rabbits)
GASTROINTESTINAL SURGERY, ILEAL BYPASS-
ILEECTOMY
M ROlHL-11901-12 Effects of metabolic surgery on the
hyperlipidemias
*• R01HL1190112 0001 Effects of metabolic surgery on
the hyperlipidemias ■ Partial ileal bypass (human)
** ROlHL-1 1901-12 0004 Effects of metabolic surgery on
the hyperlipidemias - Ileal bypass-Cholesterol dynamics
studies (rats, rabbits, dogs)
** ROlHL-11901-12 0006 Effects of metabolic surgery on
the hyperlipidemias - Drug therapy with ileal bypass
(rabbits)
** ROlHL-11901-12 0012 Effects of metabolic surgery on
the hyperlipidemias - Ileal bypass -Animal atherosclerosis
implications (pigeons, dogs, rabbits)
** ROlHL-11901-12 0013 Effects of metabolic surgery on
the hyperlipidemias - Human cholesterol and bile acids
dynamics-Meal bypass
** ROIHL 11901-12 0014 Effects of metabolic surgery on
the hyperlipidemias - Effect of bypass on gastrin levels
(dogs, human)
ROlHL-11901-12 0015 Effects of metabolic surgery on
the hyperlipidemias - Portacaval shunt for cholesterol
reduction (dogs, rabbits)
** ROlHL-11901-12 0018 Effects of metabolic surgery on
the hyperlipidemias - Jejunoileal bypass-Postoperative
complications (human)
** ROlHL-11901-12 0019 Effects of metabolic surgery on
the hyperlipidemias - Cholesterol, bileacids, lipoproteins in
obese humans
** ROlHL-11901-12 0020 Effects of metabolic surgery on
the hyperlipidemias - Jejunoileal bypass-Endogenous
animal model of obesity (rats)
P50HL-14236-05 0009 Prevention of premature
arteriosclerosis - Clinical studies on cholesterol metabolism
(human)
M POIHL- 15265-05 Program on surgical control of the
hyperlipidemias
(contd)
I
♦Excludes routine methodotogy OR covers only general projects which preclude indexing at the specific level.
••Oriente<l sipnrfirantty to atinvp <;iibip'^
M Grant has subprajects describing specific research aspects.
Sep '.(.pfnt*!- ir.! investigator's name and grant number.
OAS
** POIHL IS;6iOb 0004 Pfoitam on sutgicil conlrol ol tha
hyp«rlipid«mia] Cooidin*tin| ctntti and cantcal data
procassini facility
** POIHl l!i?6b0!> 0011 Proifam on sui(ical control ol the
hypaillpidamiai Cantral alaclrocaidiogtaptiy laboialory
(liuman)
•* POIMI 1526b Ob 0012 Proitam on sui|ical contiol ol the
hypadipldamias Cantial aitetiogiaphy Radiogidphy
lalMratocy (human)
•• POIHI 1526S05 0013 Piogtam on surgical conlrol ol the
hyparllpidamlas Clinical centar Minnesota
" POIHL 1526b0b 0014 Program on surgical control ol the
hyparilpldemias ArKansas clinical center
ROIHI lb9490b Lipoprotein metabolism in relation to
atherosclerosis (human, baboons)
ROIHL 18610 03 Eaihr intervention of age related arterial
changes (pigeon)
GASTROINTESTINAL SYSTEM (GENERAL)
SEE ALSO LIVER
SEE ALSO PANCREAS
POIHL 121b7 11 0058 Functions and mechanisms of cell
membrane ion transport Ionic and osmotic regulation in
toadtish A euryhaline aglomerulat teleost
ROIHL 1665805 Intrarenal regulation of sodium
reabsorption
ROlHL-2220101 Pharmacology and chemistry of
nudibranch toxins (guinea pigs, rats, mice)
GASTROINTESTINAL SYSTEM, ESOPHAGUS
POIHL 0630818 0043 Mechanisms and therapy of
circulatory disease Exercise and echocardiographic
examining techniques (human)
** ROIHL 22326-01 Noninvasive measurement of cardiac
output (dogs)
GASTROINTESTINAL SYSTEM, INTESTINES
** R01HL0850615 Lipemia-carbohydrate and glyceride
metabolism (human, rats)
" P01HL1167811 0039 Cardiovascular dynamics and their
control ' Capillary and interstitial fluid dynamics of the
intestine (cats)
POIHL 1583506 0012 Study of muscles related to heart
disease Contraction and energetics of visceral and
vascular smooth muscles (rabbits)
ROIHL 1809604 Vasoactive agents in splanchnic viscera
(primates, dogs)
R01HL1899403 Substance P~Occurrence, pharmacology
and physiology (mammals non-human, human)
ROlHL-20397-03 VLOL-TG metabolism in diabetes mellitis
(human, rat)
GASTROINTESTINAL SYSTEM, INTESTINES,
LARGE INTESTINE, COLON
R01HL09610-14 Control of cholesterol metabolism -Bile
acid transport
POlHL-14388-07 0191 Regulation of the circulation in
pathological states Regulation of chloride transport in
epithelial membranes (turtles)
GASTROINTESTINAL SYSTEM, INTESTINES,
MUCOSA
ROlHL-02033-23 Regulation of cholesterol esters in blood
and tissues (rat, cattle, human)
ROlHL-15930-06 Hormonal control of lipid and lipoprotein
synthesis (rats)
ROlHL-17332-04 Use of the gut for therapy of coronary
artery disease (mammals)
** POlHL-17421-05 0003 Regulation and exchange in the
microcirculation - Transcapillary fluid exchange in rat
intestinal muscle, mucosa, and mesentery
ROlHL-17818-05 Metabolism of cholesterol and cholesterol
in man (also rats, monkeys)
P50HL-19157-02 0009 Studies in cystic fibrosis and
bronchiolitis - Polyamine metabolism in cystic fibrosis
(human, rat)
ROlHL-20605-02 Microvascular responses during intestinal
absorption (rats)
GASTROINTESTINAL SYSTEM, INTESTINES,
MUCOSA, VILLI
ROlHL-20605-02 Microvascular responses during intestinal
absorption (rats)
GASTROINTESTINAL SYSTEM, INTESTINES, SMALL
INTESTINE, ILEUM
ROlHL-09610-14 Control of cholesterol metabolism- Bile
acid transport
ROlHL-18219-04 Regulation of cholesterol metabolism
(rats)
P50HL-19362-02 0009 A/S SCOR -Atherosclerosis in
nonhuman primates - Cholesterol metabolism and
intestinal microflora (baboon)
GASTROINTESTINAL SYSTEM, INTESTINES, SMALL
INTESTINE, JEJUNUM
ROlHL-1 1901-12 0018 Effects of metabolic surgery on
the hyperlipidemias - Jejunoileal bypass-Postoperative
complications (human)
ROlHL-15231-05 Mechanisms of hemodynamic changes
during digestion (dogs)
ai7
GASTROINTESTINAL SYSTEM, STOMACH,
GASTRIC JUICE
SI I Also CASIRUINIISIINAI HORMONI S, GASIRIN
ROIHI 18994 OJ Substance P Oicuirence, pharmacology
and physiology (mammals non human, human)
GASTROINTESTINAL SYSTEM, STOMACH,
GASTRIC JUICE, GASTRIC ACID
ROIHI 03181 21 002/ Hemodynamics as applied to
surgical problems Hemodynamic studies of the Gl trad
(dogs)
GASTROINTESTINAL SYSTEM, STOMACH,
GASTRIC JUICE INHIBITORS
ROIHI 22258 01 New aspects of pharmacology related to
carbonic anhydrase
GASTROINTESTINAL VISUALIZATION*
ROIHL 13885 08 9003 Cystic fibrosis and pulmonary
disease Fiberoptic bronchoscopy core facility (human,
dogs, sheep)
GASTROPODS
SEE MOLLUSKS, GASTROPODS*
GEL ELECTROPHORESIS
SEE PHYSICAL SEPARAIION. ELECTROPHORESIS, GEL*
GEL FILTRATION CHROAAATOGRAPHY
SEE PHYSICAL SEPARATION, CHROMATOGRAPHY, GEL
FILTRATION (PERMEATION)*
GEL PERMEATION CHROMATOGRAPHY
SEE PHYSICAL SEPARATION, CHROMATOGRAPHY, GEL
FILTRATION (PERMEATION)*
GELATIN
SEE ALBUMINOIDS. GEUTIN
GELS
SEE PHYSICAL PROPERTIES, COLLOIDS, GELS
GELS (DOSAGE FORM)
SEE DOSAGE FORMS
GENE EXPRESSION
SEE GENETICS, GENES, GENE EXPRESSION
GENE INSERTION INTO FOREIGN HOSTS
SEE GENETIC MANIPULATION
GENE THERAPY
SEE GENETIC DISORDERS, GENE THERAPY
GENERAL MEDICINE STUDY SECTION
Micropuncture study of kidney function
Lipid metabolism (human, rats)
Control of cholesterol metabolism -Bile
' R01HL02334-23
(rats, animals)
■ ROlHL-06481-15
' ROlHL-096 10-14
acid transport
' R01HL-0992I-13 Mechanisms related to congestive heart
failure (dogs, human, rat)
' ROlHL-10894-12 Intestinal bacteria and steroid
metabolism (human, guinea pigs, rabbits, rats)
' R01HL-I09 14-10 Renal sodium transport in experimental
aldosteronism (dogs)
' R01HL-I2827-08 Regulation of sodium excretion (dogs,
rats)
ROlHL-12990-09 Control of antidiuretic hormone secretion
and metabolism (dogs, rats, rabbits)
ROlHL-13408-05 Environmental-genetic interactions in
hypertension (rats)
ROlHL-14133-08 Intrarenal regulation of sodium
reabsorption (dogs, hamsters, rats)
ROlHL-14720-08 Factors governing the renal excretion of
acid (humans, rats)
ROlHL-14914-06
rate (rats)
R01HL-16490-04
(rats, rabbits)
ROlHL-18097-04
ROlHL-18185-04
NaO pump (dogs)
ROlHL-1936603 Renal Starling forces in experimental
conditions (rats, rabbits)
ROlHL-19463-02
(rats)
R23HL-19601-01
Autoregulation of glomerular filtration
Structural basis of nephron filtration
Pathogenesis of acute renal failure (rats)
Cardiac glycosides and diuretics-Role of
Pathophysiology of acute renal failure
Cardiac response to chronic metabolic
acidosis (rats)
** ROlHL-201 76-02 Biochemistry and genetics of salt
hypertension (rats)
** ROlHL-202 78-02 Cellular mechanisms of renin secretion
(rats)
** ROlHL-21849-02 Control of sodium transport and cellular
respiration (toad bladder)
** ROlHL-22051-01 Role of angiotensin II in vasopressin
release (human)
GENES
SEE GENETICS, GENES
GENETIC CODING
SEE GENETICS, GENETIC COOING
GENETIC COUNSELING
SEE GENETIC DISORDERS. GENETIC COUNSELING
OEN
GENETIC DEREPRfSSION
Ml MNMK.', f.lNMK KKiUIAIIOH OfdfTIC IMDIJCIION
HI I'RI '.MON III Kl KWI -".MON
GENETIC DISORDERS (SEE ALSO APPROPRIATE
CONGENITAL ABNORMAUTIES)
SI I Also BlOOl) AND HI IJISORlJl HS AMI MIA HEMOlYIlt
CONGINIIAI ((.INIRAII
SEE ALSO BIOOO AMU HF DISORDFKS CONGFNItAI
(HEREDITARY)
SEE ALSO CARDIOVA.SCIIIAR DISORDERS. HYPFRIfNSION
(SYStfMIC) GEHFTICS ASSOCIATED
SEE At SO CONGFNITAI ABNORMAlltlES
SEE ALSO CONGFNIlAl ABNORMAIIIIFS HEART DEFECTS.
ASYMMflRIC SFPTAl HYPFRIROPHY
SEE ALSO DISEASE PRONENtSS RISK
SEE ALSO GENE lies. MUTATION
SEE ALSO METABOLIC DISORUERS INBORN
** POIHL 03174 23 0005 Mechanisms of acute vascular
reaction to injury Renal small vessel didease Cell and
matrix response (human, mice)
POIHL 10436 13 0016 A mullidisciplinary study of
congenital heart disease Genetic studies of congenital
heart disease (human)
•• ROIHL 1094209 Study of genetic hypertension in ratj
ROIHL 1362606 Lipoprotein lipase and lipoprotein
removal (human, rats, bacteria)
** P50HL 14153 07 0001 Johns Hopkins Lung Center
Chronic diseases of airviays Genetic and environmental
factors in chronic pulmonary disease (human)
POIHL 1438807 0208 Regulation of the circulation in
pathological states Baroreceptor reflex function in normal
and hypertensive man
** ROIHL 1491306
(rats)
Hypertension- Genetic influence of kidney
Molecular pathology of genetic disorders
ROIHL 15125-07
in man
ROIHL 15808-06 Role of angiotensinogen in hypertension
and stroke (human, rabbits)
ROlHL-15949-05 Lipoprotein metabolism in relation to
atherosclerosis (human, baboons)
P60HL-15996 06 0009 Cincinnati comprehensive sickle
cell center - Insurance coverage of persons with sickle cell
trait and disease
POlHL-17430-05 0001 Control of coagulation - Porcine
von Willebrand's disease
ROlHL-18191-04 Models of hypoxic pulmonary
hypertension (cattle, minipigs)
POlHL-18576-03 0007 Thrombosis research program
project Relationships between coagulability and
thrombosis (human, animals)
ROIHL- 18848-03 Etiology and development of congenital
heart disease (dogs, cats)
ROlHL-18893-03
receptor (rats)
ROlHL-19930-03
newborn twins
ROlHL-20034-03
Mechanism of angiotensin action-Role of
A prospective study-Blood pressure in
•Excludes routine methodotogy OR covers only general projects which preclude indexing at the specific level.
**Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects
See Appendix for investigator's name and grant number.
Hypertension-Psychophysiologic and
genetic precursors (human)
ROlHL-20604-03 Sympathectomy-Cardiovascular and
molecular pharmacology (animals)
ROlHL-20875-02 Chronic obstructive pulmonary disease-
Familial/genetic (human)
POlHL-20948-02 0001 Molecular basis of cholesterol
metabolism - Biochemical and ultrastructural
characterization of LDL in human fibroblasts
POlHL-20948-02 0004 Molecular basis of cholesterol
metabolism - Genetic analysis of the LDL pathway (human)
ROlHL-21912-01 Biosynthesis of lipoic acid and
atherosclerosis (birds, chick embryos)
ROlHL-22261-01 Compliance of fluid spaces in advancing
hypertension (rats)
R23HL-22438-01 The etiology of genetic hypertension
(rats)
*' R23HL-22959-01 Heart development in inherited
cardiomyopathy (hamsters)
ROlHL-23194-02 Genetics of hypertension and associated
variables (human)
GENETIC DISORDERS, AUTOSOMAL RECESSIVE
CONDITIONS
SEE ALSO CONGENITAL ABNORMALITIES. NEUROLOGICAL,
DYSAUTONOMY FAMILIAL
SEE ALSO HEMOPROTEINS. HEMOGLOBINOPATHIES, SICKLE
CELL ANEMIA
SEE ALSO METABOLIC DISORDERS INBORN.
AMINOACIOOPATHIES. HOMOCYSTINURIA
SEE ALSO METABOLIC DISORDERS INBORN. CYSTIC FIBROSIS
ROlHL-19430-03 Congenital heart malformations and
situs inversus (mice)
ROlHL-22505-01 Molecular pathology of fibrinogen and
factor XIII (human, animals)
GENETIC DISORDERS, BLOOM'S SYNDROME
P01HL-090I1-15 0010 A research and resource program
in blood - Chromosome changes in human genetics
GENETIC DISORDERS, CHROMOSOME
ABNORAAALITIES
*' POlHL-04664-18 0008 Cardiovascular and lung dynamics
- Micrographic video imaging technique
** POlHL-09011-15 0010 A research and resource program
in blood - Chromosome changes in human genetics
(contd)
GEN
GENETIC DISORDERS, GENE THERAPY
SEE ALSO ENZYME THERAPY
ROlHL-20912-02 Control on non-alpha chain synthesis in
thassemic mice
** R23HL-2 1428-02 Expression of human globin in
thalassemia (human)
GENETIC DISORDERS, GENETIC COUNSELING
SEE ALSO GENETICS, KARYOTYPES
POlHL-06350-17 0015 Hemostasis research program
project - Genetics (human)
POlHL-0901115 0010 A research and resource program
m blood - Chromosome changes in human genetics
P60HL-15157-07 0001 Comprehensive center for sickle
cell disease - Screening program (human)
** P60HL15157-07 0003 Comprehensive center for sickle
cell disease - Public education
** P60HL-1 6158-07 0009 Comprehensive sickle cell center -
Counseling and social services
P60HL- 151 58-07 0011 Comprehensive sickle cell center -
Clinical services-Adult patients
M P60HL-15160-07 Center for sickle cell disease
** P60HL-15160-07 0003 Center for sickle cell disease ■
Genetic counseling in hemoglobinopathies-Dimensions,
effectiveness
** P60HL-15160-07 0017 Center for sickle cell disease -
Demonstration -Education, screening, counseling, patient
care
** P60HL-1516207 0011 Comprehensive sickle cell center -
Core program-Genetic counseling and diagnostic screening
PeOHL-15168-07 0002 Comprehensive sickle cell disease
center - Patient care
** P60HL-15168-07 0003 Comprehensive sickle cell disease
center ■ Sickle cell education and training program
P60HL-15168-07 0010 Comprehensive sickle cell disease
center ■ Sickle cell center project (children)
P60HL- 15169-05 0021 Support for center for sickle cell
disease • Multidisciplinary module system for education,
screening and counseling
" P60HL-1517005 0030 Support for center for sickle cell
anemia - Adult services -Counseling program
** P60HL-15996-06 0007 Cincinnati comprehensive sickle
cell center - Screening and counseling
** P60HL- 15999-05 0004 Miami comprehensive sickle cell
center ■ Education, screening and counseling
P60HL-1 5999-05 0005 Miami comprehensive sickle cell
center - Sickle cell clinic
P60HL-16005-05 0001 Comprehensive sickle cell center ■
Demonstration -Community service component
P60HL16008-06 0001 Wayne State University
comprehensive sickle cell center ■ Patient care system
(children, adults)
** P60HL-16008-06 0011 Wayne State University
comprehensive sickle cell center Education, screening and
counseling
** ROlHL-17465-04 Befa-thalassemia screening and genetic
counseling
M P60HL-20985-01 Northern California sickle cell center
** P60HL-20985-01 0009 Northern California sickle cell
center - Patient services (children, adults)
P60HL-20985-01 0010 Northern California sickle cell
center - Prenatal diagnosis of sickle cell anemia
POlHL-2101602 0017 Sickle cell anemia and other
hemoglobinopathies - The hereditary clinic core
M P60HL-23282-01 Comprehensive hospital/community sickle
cell center
** P60HL-2328201 9001 Comprehensive hospital/community
sickle cell center ■ Core-lnstitutionalization of education,
screening and counseling
P60HL-23282-01 9002 Comprehensive hospital/community
sickle cell center - Core-Model sickle cell service for
neighborhood health centers
GENETIC DISORDERS, METABOLIC ERRORS
SEE METABOLIC DISORDERS INBORN
GENETIC DISORDERS DIAGNOSIS*
SEE ALSO METABOLIC DISORDERS INBORN DIAGNOSIS*
SEE ALSO PREGNANCY. ANTEPARTUM DIAGNOSIS
POlHL-04664-18 0008 Cardiovascular and lung dynamics
- Micrographic video imaging technique
R01HL14700-05 Humoral and lung protease-antiprotease
role in obstructive disease (human)
" P60HL-1516207 0018 Comprehensive sickle cell center -
Biochemical and genetic studies of sickle cell anemia
(human)
P60HL16005-05 9001 Comprehensive sickle cell center -
Core laboratory and counseling (human)
ROlHL-16774-04 Genetic epidemiology of hyperlipemia
(Honolulu)
ROlHL-17551-04 Biosynthesis and metabolism of
procollagen (human, monkeys, mice)
ROlHL-18553-03 Membrane defects in familial
hypercholesteremia (human)
** ROlHL-18687-03 Pathophysiology of genetic
hypertriglycerinemias (human)
ROlHL-18723-03 Genetic heterogeneity of acid lipase-
Atherosclerosis (human)
** ROlHL-18878-03 Familial hypercholesteremia -Studies of
fibroblasts (human)
ROlHL-20070-02 Alpha-1-antitrypsin deficiency (human,
hamsters)
218
ROlHL-20807-02 Detection of familial hypercholesterolemia
(human)
** ROlHL-21 156-02 Antitrypsin and other causes of chronic
lung disease
ROlHL-21487-01 Molecular characterization of
Glanzmann's thrombasthenia (human)
ROlHL-21971-01 Atherosclerotic disease and risk factors
in twins (human)
GENETIC DISORDERS OF AUTONOMIC NERVOUS
SYSTEM
SEE CONGENITAL ABNORMALITIES, NEUROLOGICAL,
DYSAUTONOMIA FAMILIAL
GENETIC DISORDERS OF BLOOD (AND RE
SYSTEM)
SEE BLOOD AND RE DISORDERS CONGENITAL (HEREDITARY)
GENETIC ENGINEERING
SEE GENETIC MANIPULATION
GENETIC INDUCTION-REPRESSION-
DEREPRESSION
SEE GENETICS, GENETIC REGULATION, GENETIC INDUCTION-
REPRESSION-DEREPRESSION
GENETIC MANIPULATION
ROlHL-04442-20 Mitochondrial assembly and replication
(fungi, wheat)
ROlHL-15026-12 Quantitative genetic control of protein
synthesis (human, primates, mammals)
R23HL-21428-02 Expression of human globin in
thalassemia (human)
ROlHL-21831-05 Determining sequences from hemoglobin
messenger RNA (mice, chickens, rabbits)
** R23HL-22839-01 Cellular translation of liposomally-
delivered mRNA (human, mammals)
GENETIC MAPPING
** ROlHL-04442 20 Mitochondrial assembly and replication
(fungi, wheat)
M POlHL-063 14-17 Immunologic mechanisms in
cardiovascular disease
** POlHL-063 14-17 0059 Immunologic mechanisms in
cardiovascular disease - Immunogenetic response to
streptococcal antigens in man
M POlHL-09011-15 A research and resource program in
blood
** POlHL-090 11-15 0001 A research and resource program
in blood ' Genetic markers of human blood and gene
mapping (human)
** POlHL-0901115 0010 A research and resource program
in blood - Chromosome changes in human genetics
ROlHL-15026-12 Quantitative genetic control of protein
synthesis (human, primates, mammals)
POlHL-16851-04 0005 Human red cell membrane in
health and disease - Relation of hemoglobin species to
membrane properties (human)
** P60HL17265-04 0008 Community blood resource center
support - Research-Blood genetic markers as biological
probes (human)
ROlHL-20912-02 Control on non-alpha chain synthesis in
thassemic mice
ROlHL-20922-02 Control of human fetal hemoglobin
synthesis
POlHL-210 16-02 0012 Sickle cell anemia and other
hemoglobinopathies - Stimulation of Hb F synthesis in a
permanent cell line
ROlHL-221 74-01 Assembly of membranes in heart and
yeast mitochondria
GENETIC MAPPING, GENETIC MARKERS
ROlHL-04442-20 Mitochondrial assembly and replication
(fungi, wheat)
** POlHL-0901115 0001 A research and resource program
in blood - Genetic markers of human blood and gene
mapping (human)
POlHL-09011-15 0010 A research and resource program
in blood - Chromosome changes in human genetics
POlHL-09011-15 0018 A research and resource program
in blood - Hepatitis B in normal populations-Epidemiology,
risk factors and transmission
P50HL-141 53-07 0001 Johns Hopkins Lung Center-
Chronic diseases of airways - Genetic and environmental
factors in chronic pulmonary disease (human)
POlHL-16851-04 0005 Human red cell membrane in
health and disease - Relation of hemoglobin species to
membrane properties (human)
P60HL-17265-04 0008 Community blood resource center
support - Research-Blood genetic markers as biological
probes (human)
ROlHL-18473-04 Genesis of atherosclerotic lesions
(human, mules)
ROlHL-19984-02 Blood pressure and immunogenetic
factors in the young (human)
ROlHL-201 59-03 Genetic epidemiology of precursors of
hypertension (human)
POlHL-20993-02 0003 Population dynamics of arterial
cells in atherogenesis - Clonal phenomena in atherogenesis
(human, hares)
ROlHL-22301-01 Immunogenetics of chronic pulmonary
inflammation (mice)
ROlHL-22607-01 Role of apolipoprotein E in lipoprotein
metabolism (human)
GEN
ROlHL-23194-02 Genetics of hypertension and associated
variables (human)
ROlHL-23631-01 Immunogenetic factors in allergic
respiratory diseases (human)
** ROlHL-23654-01 Selected topics on blood transfusion
(rabbits, human)
GENETIC MAPPING, LINKAGE
POlHL-063 14- 17 0059 Immunologic mechanisms in
cardiovascular disease - Immunogenetic response to
streptococcal antigens in man
POlHL-09011-15 0001 A research and resource program
in blood - Genetic markers of human blood and gene
mapping (human)
POlHL-0901115 0010 A research and resource program
in blood - Chromosome changes in human genetics
POlHL-09011-15 0012 A research and resource program
in blood - Theoretical population genetics (human)
P50HL14153-07 0001 Johns Hopkins Lung Center-
Chronic diseases of airways - Genetic and environmental
factors in chronic pulmonary disease (human)
P60HL-16008-06 0016 Wayne State University
comprehensive sickle cell center - Red blood cell glycolysis
in sickle cell patients
P60HL-17265-04 0008 Community blood resource center
support ■ Research -Blood genetic markers as biological
probes (human)
** ROlHL-23 194-02 Genetics of hypertension and associated
variables (human)
GENETIC MARKERS
SEE GENETIC MAPPING, GENETIC MARKERS
GENETIC REGISTRIES AND REFERRAL CENTERS
SEE ALSO HEALTH RECORD SYSTEMS, PATIENT (DISEASE)
REGISTRIES
P60HL-I5170-05 0030 Support for center for sickle cell
anemia - Adult services-Counseling program
P60HL16005-05 9001 Comprehensive sickle cell center -
Core laboratory and counseling (human)
P01HL16769-05 0007 Pathobiologic and host defense
reactions in the lung - Immunogenetic factors in
sarcoidosis (human)
ROlHL-21088-02 Genetic patterns in deaths from Ml and
stroke in Utah
GENETIC REGULATION
SEE GENETICS, GENETIC REGUUTION
GENETIC STRAINS
SEE BIOLOGY, SYSTEMATIC, GENETIC STRAINS
GENETICS
SEE ALSO BIOLOGY, SYSTEMATIC, EVOLUTION BIOCHEMICAL
SEE ALSO BLOOD GROUPS
SEE ALSO CELL DIVISION
SEE ALSO IMMUNOGENETICS (GENERAL)
SEE ALSO NEOPLASMS GENHICS
SEE ALSO NUCLEIC ACIDS REPAIR, DNA REPAIR (ENZYME)
SEE ALSO PSYCHOGENETICS-BEHAVIORAL GENETICS
SEE ALSO TISSUE COMPATIBILITY-TRANSPLANT,
ISOALLOIMMUNITY
** POlHL-05314-17 0055 Immunologic mechanisms in
cardiovascular disease - Genetics and cell biology
ROIHL- 13694-08 Capillary basement membrane in
cardiovascular disease (human, rats)
** P50HL-19362-02 0003 A/S SCOR-Atherosclerosis in
nonhuman primates - Heritability of characters related to
atherosclerosis (baboons)
P50HL-19362-02 0012 A/S SCOR-Atherosclerosis in
nonhuman primates - Induction of chronic hypertension by
salt loading (baboon)
GENETICS, BEHAVIORAL
SEE PSYCHOGENETICS-BEHAVIORAL GENCTICS
GENETICS, CHROMOSOME COMPLEMENT,
GENOME
POlHL-06285-18 0178 Cardiovascular-respiratory
physiology and biochemistry - Biochemical regulation of
hypertrophy (rats, rabbits)
POlHL-11310-12 0100 Mechanisms of cardiovascular
disease - Structure and replication of arenavirus and
Bunyamweraviruses
POlHL-21016-02 0012 Sickle cell anemia and other
hemoglobinopathies - Stimulation of Hb F synthesis in a
permanent cell line
GENETICS, CHROMOSOMES
SEE ALSO GENETICS. KARYOTYPES
ROlHL-02558-22 Structure-function relationships in the
heme proteins (human, cattle)
GENETICS, CHROMOSOMES, CHROMATIN
ROlHL-05360-19 Cholesterol biosynthesis and its control
in liver (rats)
POlHL-0628518 0193 Cardiovascular-respiratory
physiology and biochemistry ■ Hormonal regulation of
sodium transport-Aldosterone (rats, toads)
POlHL-09011-15 0019 A research and resource program
in blood ■ The transport mechanism of mRNA (rat, yeast.
ascites cells)
ROIHL- 1534 1-06 Lung hormonal and chromosomal
regulation (rats, rabbits)
(contd)
^
•Excludes routine methodokigy OR cavers only general projects which preclude indexing at the specific level.
**Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
OIN
P«ONl 1 7269 04 0020 Nitlond heart and bkwd vaSMi
tesaaich and damonsliation contai Nucleic acid and
prolain metabolism in growth and development ot heart
(rat)
ROIHl ?030002 HIstone Hb and avian eiYthropolesis
(chickens, rabbits)
ROIHI ??367 01 Cslroien receptoij in very low density
lipoproteins (chicken livers)
GENETICS, CHROMOSOMES, SEX
CHROMOSOMES
ROIHL lb026 12 Quantitative genetic control ol proletn
synthesis (human, primates, mammals)
GENETICS, CYTOGENETICS
SEE. ALSO CLLL DIVISION. MITOSIS
POIHl'03i;4 23 0010 Mechanisms ol acute vascular
rMCtion to injury Search lor mutagens in the human
blood (bacteria, animals)
ROIHL 06481 15 Lipid metabolism (human, rats)
POIHL 09011 15 0010 A research and resource program
in blood Chromosome changes in human genetics
GENETICS, GENES
ROIHL 20961 02 Hemoglobin Ychain genes-Evolution and
inducibility (monkeys, human)
GENETICS, GENES, ALLELES
ROlHL-22174'01 Assembly ol membranes in heart and
yeast mitochondria
GENETICS, GENES, GENE EXPRESSION
SEE ALSO GENETICS. GENETIC REGUUTION. GENETIC
INDUCTIONREPRESSIONDEREPRESSION
SEE ALSO GENETICS. GENOTYPES
POIHL'03174'23 0006 Mechanisms ol acute vascular
reaction to injury - Atherosclerotic plaque studies using
mosaic analysis (human)
P01HL0628518 0186 Cardiovascular respiratory
physiology and biochemistry Leukocyte hormone receptors
and cyclic nucleotides (tissue culture)
POlHL-06285'18 0193 Cardiovascularrespiratory
physiology and biochemistry - Hormonal regulation of
sodium transport-Aldosterone (rats, toads)
POlHL-0631417 0059 Immunologic mechanisms in
cardiovascular disease - Immunogenetic response to
streptococcal antigens in man
PO1HLO635017 0015 Hemostasis research program
project • Genetics (human)
PO1HL0901115 0010 A research and resource program
in blood ' Chromosome changes in human genetics
** P01HLU35M2 0004 Cellular and molecular
mechanisms of myocardial function Molecular
mechanisms of contractile function and differentiation
(animals)
PO1HL12738-10 0001 Physiologic pharmacology and its
clinical applications - Clinical pharmacology of cardioactive
drugs (human)
R01HL12833-09 Genetic and environmental influences on
lung disease (human)
P50HL-14153-07 0001 Johns Hopkins Lung Center-
Chronic diseases of airways - Genetic and environmental
factors in chronic pulmonary disease (human)
ROIHL-1469206 Alpha 1 antitrypsin deficiency and
pulmonary disease (human)
ROlHL-14865-07 Biochemical studies on the pathogenesis
of emphysema (human, rats)
ROlHL-15125-07 Molecular pathology of genetic disorders
in man
P60HL-1515807 0004 Comprehensive sickle cell center -
Expression of abnormal hemoglobin synthesis in the
neonate and young child
P60HL-1515807 0016 Comprehensive sickle cell center -
Biochemical studies in sickle cell anemia (human)
P60HL-1516207 0018 Comprehensive sickle cell center -
Biochemical and genetic studies of sickle cell anemia
(human)
POlHL-15832-06 0004 Chemical-structural predispositions
to lung injury - Proteolytic activity leucocytes in patients
with obstructive lung disease
** P01HL16851-04 0005 Human red cell membrane in
health and disease - Relation of hemoglobin species to
membrane properties (human)
ROlHL-17194-03 Comparison of two inherited forms of
alpha-1-antitrypsin (human)
** P60HL-17265-04 0008 Community blood resource center
support ■ Research-Blood genetic markers as biological
probes (human)
** ROlHL-17882-04 Regulation of HMG-COA reductase and
sterol synthesis (human, mammals)
ROlHL-17909-04 Drug treatment of vascular scleroprotein
defects (human, turkeys)
ROlHL-18723-03 Genetic heterogeneity of acid lipase-
Atherosclerosis (human)
R01HL18876-03 Human alpha-1-antitrypsin synthesis in
vitro
P50HL19157-02 0008 Studies in cystic fibrosis and
bronchiolitis - Serum proteins in cystic fibrosis (human)
ROlKL-19430-03 Congenital heart malformations and
situs inversus (mice)
POlHL-19717-02 0002 Response of the lung to injury -
Prolyl hydroxylase, lysyl hydroxylase and lung collagen
biosynthesis (rabbits)
Genetic patterns in deaths Irom Ml and
Collagen synthesis in pulmonary fibrosis
ai9
** ROIHL 70301 02 Genelio ol glycoiyltranilerauii in
human blood
ROIHL 20905 02 Synthesis at lelal hemoglobin in erythroid
cells (sheep, human)
ROIHL 20912 02 Control on non alpha chain synlhcils In
thassemic mice
** ROllll 20922 02 Contiol ol human letal hemoglobin
synthesis
POIHI 21016 02 0012 Sickle cell anemia and other
hemoglobinopathies Stimulation ol Hb F synthesis in a
permanent cell line
ROIHL 21088 02
stroke in Utah
•• R23HL2150402
cells (human)
ROIHL 22040 01 Regulation ol lysyl cross linking in
vascular tissue (rats, turkeys)
ROIHL 22729 01 Intracellular degradation ol newly
synthesized collagen (human, chick, rabbit)
** ROIHL 23194 02 Genetics ol hypertension and associated
variables (human)
ROIHL 23588 01 NOV infection-Analysis at the subcellular
level (chickens)
NOIHV 62955-04 Data collection In clinical pathology and
morbid anatomy (men)
GENETICS, GENES, GENE EXPRESSION, LETHALS
ROlHL-13831'08 Factors regulating embryonic cardiac
morphogenesis (chick, salamandra)
** ROIHL 22550-02 Genetic cardiomyopathies in salamanders
and hamsters
GENETICS, GENES, GENE EXPRESSION,
PLEIOTROPISM
POIHL 090 11-15 0001 A research and resource program
in blood Genetic markers of human blood and gene
mapping (human)
ROlHL-22174 01 Assembly of membranes in heart and
yeast mitochondria
GENETICS, GENES, GENE INTERACTION,
COMPLEMENTATION
ROIHL 19646-03 An immunologic study of hemoglobin
variation in man
GENETICS, GENES, OPERON, REGULATORY
GENE
** ROlHL-221 74-01 Assembly of membranes in heart and
yeast mitochondria
GENETICS, GENES, OPERON, STRUCTURAL
GENE
P60HL 2098501 0005 Northern California sickle cell
center - Molecular mechanism of alpha thalassemia-
Relation to sickle cell anemia (human)
GENETICS, GENETIC CODING
SEE ALSO GENETICS. GENETIC REGUUTION, GENETIC
INDUCTION-REPRESSIONOEREPRESSION
SEE ALSO GENETICS. GENETIC REGULATION, GENETIC
INDUCTION-REPRESSION-DEREPRESSION,
TRANSCRIPTION
SEE ALSO GENETICS, GENCTIC REGUUTION. GENETIC
INDUCTION-REPRESSION DEREPRESSION,
TRANSUTION
SEE ALSO PROTEINS BIOSYNTHESIS
P60HL-151 58-07 0016 Comprehensive sickle cell center -
Biochemical studies In sickle cell anemia (human)
ROlHL-177 10-04 Selective replication of hemoglobin genes
(mice, ducks, human)
GENETICS, GENETIC REGULATION
SEE ALSO NUCLEOPROTEINS, NONHISTONE (GENERAL)
" ROlHL-04442-20 Mitochondrial assembly and replication
(fungi, wheat)
POlHL-0628518 0186 Cardiovascular-respiratory
physiology and biochemistry - Leukocyte hormone receptors
and cyclic nucleotides (tissue culture)
** POlHL-090 11-15 0009 A research and resource program
in blood - Control of RNA synthesis in nucleated cells
(yeast, ascites cell)
POlHL-09011-15 0015 A research and resource program
in blood - Regulation of synthesis and transport of diverse
proteins in liver (rats)
ROlHL-13831-08 Factors regulating embryonic cardiac
morphogenesis (chick, salamandra)
" P50HL-141 64-07 0041 A/S SCOR-Comparative and
experimental atherosclerosis - Nonhuman primate pediatric
atherosclerosis risk factor
*• ROlHL-15026-12 Quantitative genetic control of protein
synthesis (human, primates, mammals)
** R01HL-15341-06 Lung hormonal and chromosomal
regulation (rats, rabbits)
** ROlHL-165 12-04 Lipoprotein metabolism and hormonal
regulation (chickens)
** ROlHL-16654-06 Regulation in developing erythroid cells
(human)
ROlHL-18723-03 Genetic heterogeneity of acid llpase-
Atherosclerosis (human)
ROlHL-20939-02 Regulation of fetal hemoglobin in
humans
** R23HL-21663-01 Regulation of collagen biosynthesis
(chick, embryo)
OEN
ROIHI 22301 01 Iminunoitrwlict ol chronic pulmonery
inllflinmation (mice)
GENETICS, GENETIC REGULATION. GENETIC
INDUCTION-REPRESSION-DEREPRESSION
Sll AISIIIN/rMI INIJU(.ll(INRlrRI',',l(JNUIHII'HI','.irjN
ROIHl 02558 2? Slrudurr function relatwnthipt in the
heme proteins (human, cattle)
POIHt 16251 06 0001 Mrmlirane bound en/ymet in heart
and other li\%ues Regulation ot cardiac kuccinate
dehydrogenase (yeasts, mammals)
POIHL 16251 06 0004 Membrane bound en/ymei in heart
and other tissues Biosynthesis and degradation ol
succinate dehydrogenase, histidyl (yeast, mammal)
P60HL 17269 04 0020 National heart and blood vessel
research and demonstration center Nucleic acid and
protein metabolism in growth and devetopment ot heart
(rat)
POIHL 17430 05 0001 Control of coagulation Porcine
von Willebrand s disease
P50HL 1919002 0003 Pulmonary SCOR Pathophysiology.
management ol IRDS Type II cells Regulation and
differentiation (rat)
ROIHL 2255002 Genetic cardiomyopathies in salamanders
and hamsters
GENETICS, GENETIC REGULATION, GENETIC
INDUCTION-REPRESSION-DEREPRESSION,
INDUCERS
ROIHL 16904 03 Regulation of smooth muscle cells in
arteriosclerosis (rabbit aorta)
ROlHL-20961 02 Hemoglobin Ychain genes -Evolution and
inducibility (monkeys, human)
GENETICS, GENETIC REGULATION, GENETIC
INDUCTION-REPRESSION-DEREPRESSION,
REPRESSORS
POIHL 09011 15 0009 A research and resource program
in blood - Control of RNA synthesis in nucleated cells
(yeast, ascites cell)
P60HL-ie005-05 0013 Comprehensive sickle cell center
Study of regulation of erythropoiesis in vitro (human, rat,
hamster, rabbit)
GENETICS, GENETIC REGULATION, GENETIC
INOUCTION-REPRESSION-DEREPRESSION,
TRANSCRIPTION
ROlHL-04442 20 Mitochondrial assembly and replication
(fungi, wheat)
** POlHL-09011-15 0009 A research and resource program
in blood - Control of RNA synthesis in nucleated cells
(yeast, ascites cell)
R01HL09172-15 Protein and RNA synthesis in heart
muscle (rats)
POlHL-1 1310-12 0100 Mechanisms of cardiovascular
disease - Structure and replication of arenavirus and
Bunyamweraviruses
** ROlHL-15619-05 Regulation of prothrombin synthesis in
cultured cells (rats)
ROlHL-16512-04 Lipoprotein metabolism and hormonal
regulation (chickens)
POlHL-19737-02 0003 Cellular and molecular aspects of
respiratory physiology - Cortisol-dependent alterations in
lung type II cells (rats)
ROlHL-20899-02 Cellular mechanisms of hemoglobin f
regulation (human)
ROlHL-20920-01 Control of hemoglobin synthesis (baboon)
ROlHL-20922-02 Control of human fetal hemoglobin
synthesis
R23HL-2142802 Expression of human globin in
thalassemia (human)
ROlHL-22981-17 Membrane-associated functions in
microorganisms (bacteria, protozoa)
ROlHL-23736-04 Sickle cell anemia and hemoglobin
synthesis (monkeys)
GENETICS, GENETIC REGULATION, GENETIC
INDUCTION-REPRESSION-DEREPRESSION,
TRANSLATION
ROlHL-09172-15 Protein and RNA synthesis in heart
muscle (rats)
P50HL-1506207 0009 Study of lipoproteins, artery wall,
and atherosclerosis - Plasma lipoprotein biosynthesis
(Rhesus monkeys)
** ROlHL-15519-05 Regulation of prothrombin synthesis in
cultured cells (rats)
** P60HL-16005-05 0013 Comprehensive sickle cell center -
Study of regulation of erythropoiesis in vitro (human, rat,
hamster, rabbit)
R01HL16512-04 Lipoprotein metabolism and hormonal
regulation (chickens)
R0U;L-17882-04 Regulation of HMG-COA reductase and
sterol synthesis (human, mammals)
Control of hemoglobin synthesis (baboon)
Control of human fetal hemoglobin
Control of protein metabolism in heart
'Excludes routine methodotogy OR covers only general projects which preclude indexing
"Oriented significantly to above subject.
at the specific level.
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
R01HL-20920-01
ROlHL-20922-02
synthesis
ROlHL-22651-01
muscle
R23HL-22839-01 Cellular translation of liposomally-
delivered mRNA (human, mammals)
ROlHL-22981-17 Membrane-associated functions in
microorganisms (bacteria, protozoa)
(contd)
GEN
ROlHL-23736-04 Sickle cell anemia and hemoglobin
synthesis (monkeys)
ROlHL-24048-01 Regulation of hemoglobin synthesis In
chick embryos
GENETICS, GENOTYPES
ROlHL-04442-20 Mitochondrial assembly and replication
(fungi, wheat)
POlHL-06350-17 0015 Hemostasis research program
project • Genetics (human)
R01HL1190112 0020 Effects of metabolic surgery on
the hyperlipidemias - Jejunoileal bypass-Endogenous
animal model of obesity (rats)
R01HL12745-10 Enzymes and inhibitors of cholesterol
biosynthesis (rats, human, swine)
" ROlHL-1340805 Environmental-genetic interactions in
hypertension (rats)
P50HL14159-08 0021 Specialized center of research in
hypertension ■ Genetic studies of the physiology of
hypertension (human, rats)
ROlHL-14913-06 Hypertension-Genetic influence of kidney
(rats)
R01HL1616605 Structure of alphal-antitrypsm in
relation to emphysema (human)
ROlHL-2007002 Alphal-antitrypsin deficiency (human,
hamsters)
** ROlHL-20159-03 Genetic epidemiology of precursors of
hypertension (human)
ROlHL-20301-02 Genetics of glycosyltransferases in
human blood
ROlHL-20712-02 Characterization of the B proteins of
serum lipoproteins (human)
NOlHR-72921-01 Cystic fibrosis factor identification and
quantification (human)
NOlHR-72922-01 Cystic fribrosis factor identication and
quantification (human)
GENETICS, GENOTYPES, HETEROZYGOTES
SEE ALSO GENETIC DISORDERS, AUTOSOMAL RECESSIVE
CONDITIONS
" P50HL-1936202 0005 A/S SCOR-Afherosclerosis in
nonhuman primates ■ Hybridization to produce primate
model of atherosclerosis (baboon. Rhesus)
ROlHL-20912-02 Control on non-alpha chain synthesis in
thassemic mice
N01HR-72920-01 Identify and quantify cystic fibrosis
factors (human)
GENETICS, GENOTYPES, HOMOZYGOTES
POlHL-09011-15 0012 A research and resource program
in blood • Theoretical population genetics (human)
ROlHL-17898-03 Cell membranes and plasma lipoproteins
(human, swine)
NOlHR-72920-01 Identify and quantify cystic fibrosis
factors (human)
GENETICS, KARYOTYPES
SEE ALSO GENETICS, POPUUTION GENETICS HUMAN
POlHL-0466418 0008 Cardiovascular and lung dynamics
■ Micrographic video imaging technique
POlHL-0901115 0010 A research and resource program
in blood - Chromosome changes in human genetics
P01HL19737-02 0003 Cellular and molecular aspects of
respiratory physiology - Cortisol-dependent alterations in
lung type II cells (rats)
POlHL-21016 02 0012 Sickle cell anemia and other
hemoglobinopathies - Stimulation of Hb F synthesis in a
permanent cell line
GENETICS, MICROBIAL
SEE ALSO GENETICS, SOMATIC CELL AND TRANSFORMATION
SEE ALSO GENETICS. SOMATIC CELL AND TRANSFORMATION.
TRANSDUCTION
SEE ALSO NUCLEIC ACIDS. RNA VIRAL
POlHL-06314-17 0057 Immunologic mechanisms in
cardiovascular disease - Antigens in cardiovascular disease
(human)
POlHL-06314-17 0059 Immunologic mechanisms in
cardiovascular disease - Immunogenetic response to
streptococcal antigens in man
POlHL-1131012 0100 Mechanisms of cardiovascular
disease ■ Structure and replication of arenavirus and
Bunyamweraviruses
GENETICS, MUTAGENS
SEE ALSO ANTIMITOTIC AGENTS
SEE ALSO CONGENITAL ABNORMALITIES, TERATOGENIC
AGENTS
SEE ALSO NEOPLASTIC TRANSFORMATION, CARCINOGENS
(GENERAL)
** POlHL-03174-23 0010 Mechanisms of acute vascular
reaction to injury ■ Search for mutagens in the human
blood (bacteria, animals)
** P01HL03174-23 0011 Mechanisms of acute vascular
reaction to injury - Mutagen metabolism by artery wall in
etiology of atherosclerosis (human, animals)
ROlHL-1792104 Peroxy radicals to prostaglandins in
vessels and lung
GENETICS, MUTATION
POlHL-03174-23 0010 Mechanisms of acute vascular
reaction to injury • Search for mutagens in the human
blood (bacteria, animals)
220
ROlHL-1502612 Quantitative genetic control of protein
synthesis (human, primates, mammals)
POlHL-18645-03 0003 Biology of the artery wall and
atherosclerosis ■ Synthesis of connective tissue proteins by
smooth muscle cells (human, monkeys)
ROlHL-20070-02 Alphal-antitrypsin deficiency (human.
hamsters)
ROlHL-20161-02 Role of gamma-carboxyglutamic acid in
blood coagulation (human, cattle)
ROlHL-20912 02 Control on non-alpha chain synthesis in
thassemic mice
POlHL-20948-02 0004 Molecular basis of cholesterol
metabolism - Genetic analysis of the LDL pathway (human)
** POlHL-2 10 16-02 0001 Sickle cell anemia and other
hemoglobinopathies - Supramolecular models of Hb S-
Mutational and EM approach
POlHL-21016-02 0003 Sickle cell anemia and other
hemoglobinopathies - Role of non-S hemoglobin in gelation
and sickling
GENETICS, MUTATION, CHROMOSOME
MUTATION, DELETION
POlHL-09011-15 0010 A research and resource program
in blood - Chromosome changes in human genetics
P60HL-20985-01 0005 Northern California sickle cell
center - Molecular mechanism of alpha thalassemia-
Relation to sickle cell anemia (human)
GENETICS, MUTATION, GENE MUTATION,
FRAMESHIFT
ROIHL 18553-03 Membrane defects in familial
hypercholesteremia (human)
GENETICS, MUTATION, GENE MUTATION, POINT
MUTATION
ROlHL-18553-03 Membrane detects in familial
hypercholesteremia (human)
GENETICS, MUTATION, GENOME MUTATION,
TRISOMY
ROlHL-20899-02 Cellular mechanisms of hemoglobin F
regulation (human)
GENETICS, MUTATION, MUTANTS*
SEE ALSO BIOLOGY. SYSTEMATIC. GENETIC STRAINS
ROlHL-16927-05 Structure and function of normal and
abnormal hemoglobin (human)
ROlHL-17882-04 Regulation of HMG-COA reductase and
sterol synthesis (human, mammals)
** POlHL-2 10 16-02 0014 Sickle cell anemia and other
hemoglobinopathies - Human hemoglobin mutants with
abnormal oxygen binding
POlHL-21016-02 0017 Sickle cell anemia and other
hemoglobinopathies - The hereditary clinic core
ROlHL-221 74-01 Assembly of membranes in heart and
yeast mitochondria
R01HL-22550-02 Genetic cardiomyopathies in salamanders
and hamsters
GENETICS, MUTATION, MUTANTS,
TEMPERATURE SENSITIVE MUTANTS*
ROlHL-23588-01 NOV infection-Analysis at the subcellular
level (chickens)
GENETICS, PHARMACOGENETICS*
** ROlHL-04457-20 Cellular aspects of active transport (fish,
rabbits, anurans. turtles)
GENETICS, POPULATION GENETICS,
INBREEDING
SEE ALSO GENETICS. GENOTYPES. HOMOZYGOTES
*• ROlHL-177 54-03 Pathogenesis and prevention of
hypertension sequelae (rats)
GENETICS, POPULATION GENETICS ANIMAL
ROlHL-01648-31 Blood coagulation and hemophilia (dogs,
swine)
POlHL-06835-17 0017 Cardiovascular disease - Studies
on obese hypertensive rats
ROlHL-09902-13 Comparative study of coagulation and
vascular disease (animals)
P50HL-141 59-08 0021 Specialized center of research in
hypertension - Genetic studies of the physiology of
hypertension (human, rats)
ROlHL-18824-03 Mechanisms of heart failure in
myopathic hamster
ROlHL-19175-03 Pituitary modulation of micro-and macro-
vascular disease (human, rats)
ROlHL-20961-02 Hemoglobin Y-chain genes-Evolution and
inducibility (monkeys, human)
GENETICS, POPULATION GENETICS HUIMAN
SEE ALSO GENETIC DISORDERS. GENETIC COUNSELING
SEE ALSO GENETICS. KARYOTYPES
ROlHL-03429-18 Central nervous system and coronary
heart disease (human)
POlHL-0631417 0057 Immunologic mechanisms in
cardiovascular disease - Antigens in cardiovascular disease
(human)
POlHL-063 14-17 0059 Immunologic mechanisms in
cardiovascular disease - Immunogenetic response to
streptococcal antigens in man
** POlHL-063 50-17 0015 Hemostasis research program
project - Genetics (human)
GEN
M POlHL-09011-15 A research and resource program in
blood
POlHL-09011-15 0001 A research and resource program
in blood - Genetic markers of human blood and gene
mapping (human)
** POlHL-09011-15 0012 A research and resource program
in blood - Theoretical population genetics (human)
POlHL-09011-15 0018 A research and resource program
in blood - Hepatitis B in normal populations-Epidemiology,
risk factors and transmission
ROlHL-12833-09 Genetic and environmental influences on
lung disease (human)
POlHL-13108-09 0002 Clinical heart transplantation •
Preoperative immunologic studies of cardiac recipients
POIHL- 13 108-09 0009 Clinical heart transplantation - B
cell alloantigens in cardiac allograft compatibility (human)
** P50HL-14141-05 0001 SCOR for atherosclerosis in
childhood - Clinical implications (infants and children)
P50HL-14153-07 0001 Johns Hopkins Lung Center-
Chronic diseases of airways - Genetic and environmental
factors in chronic pulmonary disease (human)
** P50HL-14159-08 0021 Specialized center of research in
hypertension - Genetic studies of the physiology of
hypertension (human, rats)
P50HL 14230-07 0088 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Coronary risk factors in school children-
The Muscatine study
P50HL-14236-05 0001 Prevention of premature
arteriosclerosis - Metabolism and transport of cholesterol
and vitamin A (human, rats)
P50HL-14237-07 0005 Support for arteriosclerosis center
- Genetic determinants of apolipoprotein variability in
lipoproteins (human)
ROlHL-14700-05 Humoral and lung protease-antiprotease
role in obstructive disease (human)
POIHL 14985-07 0004 Adaptation to hypoxia - Control of
breathing in respiratory failure (human, dogs)
POlHL-14985-07 0008 Adaptation to hypoxia - Ventilatory
drive and exercise capacity (human, dogs)
P50HL-15103-07 0001 A/S SCOR-Early natural history of
arteriosclerosis - Clinical research-Bogalusa heart study
(children)
P60HL-15158-07 0016 Comprehensive sickle cell center -
Biochemical studies in sickle cell anemia (human)
P60HL- 15162-07 0007 Comprehensive sickle cell center -
Core program-Demographic studies (human)
ROlHL-15308-07 Assays for peptides of lipoproteins .
(human) |
** ROlHL-15614-04 Heredity and oxygen-Effects on health of ^
heart-lungs (South America)
P60HL-16005-05 9001 Comprehensive sickle cell center -
Core laboratory and counseling (human)
** P60HL-16008-06 0016 Wayne State University
comprehensive sickle cell center - Red blood cell glycolysis
in sickle cell patients
P60HL-16008-06 0020 Wayne State University
comprehensive sickle cell center - Genetic and physiological
studies of sickle cell anemia (human)
ROlHL-16166-05 Structure of alphal-antitrypsin in
relation to emphysema (human)
POlHL-16769-05 0007 Pathobiologic and host defense
reactions in the lung - Immunogenetic factors in
sarcoidosis (human)
** ROlHL-16774-04 Genetic epidemiology of hyperlipemia
(Honolulu)
P60HL-17265-04 0008 Community blood resource center
support - Research-Blood genetic markers as biological
probes (human)
ROlHL-18687-03 Pathophysiology of genetic
hypertriglycerinemias (human)
** ROlHL-18723-03 Genetic heterogeneity of acid lipase-
Atherosclerosis (human)
ROlHL-19567-03 Impact of emotion on coronary arteries
(human)
ROlHL-19858-03 UMMC-Blood pressure precursors and
consequences (human)
ROlHL-19859-03 Epidemiological studies, precursors of
hypertension (human)
R01HL-19864-03 0003 Blood pressure of children and
young adults - Heart rate and blood pressure-Consistency
in infancy (human)
ROlHL-19870-03 Hypertensive progeny-Physical and
humoral precursor search
ROlHL-19962-03 High blood pressure in young people in
Tecumseh
** ROlHL-19984-02 Blood pressure and immunogenetic
factors in the young (human)
ROlHL-20005-03 Factors in blood pressure levels of
children
ROlHL-20034-03 Hypertension-Psychophysiologic and
genetic precursors (human)
ROlHL-20159-03 Genetic epidemiology of precursors of
hypertension (human)
ROlHL-20391-03 Polydisperse LDL-Structure. metabolism
and function (human)
ROlHL-20655-02 Autonomic predictors of hypertension in
children
ROlHL-20807-02 Detection of familial hypercholesterolemia
(human)
ROlHL-20905-02 Synthesis of fetal hemoglobin in erythroid
cells (sheep, human)
(contd)
•Excludes routine methodology OR covers only general projerts which preclude indexing at the specific level.
**0rjeirted significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
OIN
aai
OlO
ROIHl ?09ei 0? Htmoilobin Y chiln |«ni] Evolution and
inducibility (monktyjb human)
** ROIHL 2108802 G«n«tic pattxii] In dtalhs lioin Ml and
sitolia m Utah
" ROIHL 22298 02 Oiigins ol hypartension (human)
ROIHL 22607 01 Rol« ot ipolipopiotein L m hpopfottin
malabolism (human)
ROIHL 23194 02 Gtntlics of hyptitansion and associated
vaniblas (human)
ROIHL 23631 01 lmmuno|enetic lactorj in allergic
respliatoiy diseases (human)
NOIHR 6293S 02 Histocompatibility antigens-Evolution ot
respiiatoiy hypersensitivity (human)
NOIHR 7292001 ldantl^ and quantl^ cystic fibrosis
lictofs (human)
l«01HV 12156 10 Lipid research clinic
NOIHV 12157 14 Lipid research clinic (human)
NOIHV 12158 10 Establishment of a lipid research clinic
NOIHV 22914 08 Establishment ol a lipid research clinic
GENETICS, RECOMBINATION
ROIHL'04442 20 Mitochondrial assembly and replication
(tungi. wheat)
POIHI 09011 IS 0012 A research and resource program
in blood Theoretical population genetics (human)
GENETICS, SOMATIC CELL AND
TRANSFORAAATION
SEE ALSO BIOLOGY. POLYIWORPHISM
SEE ALSO CELL DEDIFFERENTIATION
SEE ALSO GROWTH ABNORMAL, METAPUSIA
SEE ALSO TISSUE MOSAICISM
SEE ALSO VIRUS CHARACTERISTICS. TRANSFORMING VIRUSES
POIHL'03174 23 0010 Mechanisms of acute vascular
reaction to injury Search for mutagens in the human
blood (bacteria, animals)
" P01HL20948-02 0004 Molecular basis of cholesterol
metabolism - Genetic analysis ot the LOL pathway (human)
R23HL-22839'01 Cellular translation of liposomally-
delivered mRNA (human, mammals)
GENETICS, SOMATIC CELL AND
TRANSFORMATION, TRANSDUCTION
** R01HL1999502 Sensory transduction in cardiac
mechanoreceptors (cats, fi^gs. rats)
GENETICS-ASSOCIATED HYPERTENSION
SEE CARDIOVASCULAR DISORDERS. HYPERTENSION
(SYSTEMIC). GENETICS-ASSOCIATED
GENETICS OF CANCER (NEOPLASMS)
SEE NEOPLASMS GENETICS
GENETICS STUDY SECTION
ROIHL'15026'12 Quantitative genetic control of protein
synthesis (human, primates, mammals)
R01HL17465-04 Betathalassemia screening and genetic
counseling
R01HL17710-04 Selective replication of hemoglobin genes
(mice, ducks, human)
ROlHL-1872303 Genetic heterogeneity of acid lipase--
Atherosclerosis (human)
R01HL18876-03 Human alpha-1-antitrypsin synthesis in
vitro
ROlHL-20301-02 Genetics of glycosyltransferases in
human blood
ROlHL-2096102 Hemoglobin Y-chain genes-Evolution and
inducibility (monkeys, human)
GENOME
SEE GENETICS. CHROMOSOME COMPLEMENT. GENOME
GENOTYPES
SEE GENETICS. GENOTYPES
GENTAMICIN
SEE ANTIBIOTICS. GENTAMICIN
GEOGRAPHICAL SITES, AFRICA
** P01HL-08974-14 0028 Natural and experimental
atherosclerosis ■ Geographic pathology of atherosclerosis
and coronary heart disease (human)
GEOGRAPHICAL SITES, N. AMERICA, CANADA
NOlHV-42911-07 ECG center for prevention of coronary
heart disease (human)
GEOGRAPHICAL SITES, S. AMERICA
** POlHL-08974-14 0028 Natural and experimental
atherosclerosis - Geographic pathology of atherosclerosis
and coronary heart disease (human)
ROlHL-1561404 Heredity and oxygen-Effects on health of
heart-lungs (South America)
GEOGRAPHICAL SITES, S. AMERICA, BRAZIL
ROlHL-16774-04 Genetic epidemiology of hyperlipemia
(Honolulu)
GEOGRAPHICAL SITES, S. AMERICA, CHILE
ROIHL-15614-04 Heredity and oxygen-Effects on health of
heart-lungs (South America)
GEOGRAPHICAL SITES, S. AMERICA, PERU
ROlHL-15614-04 Heredity and oxygen-Effects on health of
heart-lungs (South America)
GEOGRAPHICAL SITES, EUROPE,
SCANDINAVIAN COUNTRIES
ROIHI 0469/ 1/ International hoart dlitiM «pldtnilolO|y
(human)
GEOGRAPHICAL SITES, UNITED STATES
ROIHL 03341 11 Epidemiology ol atherosclerosis In Evans
Co Georgia
" POIHL 08974 14 0028 Natural and experimental
atherosclerosis Geographic pathology ol atherosclerosis
and coronary heart disease (human)
GEOGRAPHICAL SITES, UNITED STATES, PUERTO
RICO
NOIHV 42902 08 Epidemiological studies ol coronary heart
disease (human)
GEO-ORIENTATION
SEE ENVIRONMENT. ORIENTATION
GERIATRICS
SEE AGING
GERMICIDES, THERAPEUTIC
SEE COMMUNICABLE DISEASE CONTROL AGENTS
GESTATIONAL AGE (INTERIOR GESTATION)
SEE PREGNANCY. EMBRYO FETUS, GESTATIONAL AGE
GESTATIONAL DIABETES
SEE CARBOHYDRATES METABOLISM DISORDERS. DIABETES
IN PREGNANCY
GHETTO AREAS
SEE SOCIOENVIRONMENT. URBAN POVERTY AREAS
GHOST ERYTHROCYTE
SEE MEMBRANE. ERYTHROCYTE GHOST AND MEMBRANE
GILLS
SEE RESPIRATORY SYSTEM. GILLS
GINGIVA
SEE DENTAL STRUCTURE. GINGIVA
GLANDS
SEE ENDOCRINOLOGY. ENDOCRINES
SEE ORAL-PHARYNGEAL. SALIVARY GUNDS
SEE REPRODUCTIVE SYSTEM FEMALE. MAMMARY GUNDS
GLASS
SEE SILICATES, GLASS
GLASS ACTIVATION FACTOR (FACTOR XII)
SEE BLOOD COAGULATION. HAGEMAN FACTOR
GLAUCOMA
SEE EYE DISORDERS, GUUCOMA
GLOBINS
SEE ALSO HEMOPROTEINS, HAPTOGLOBINS
SEE ALSO HEMOPROTEINS, HEMOGLOBIN
SEE ALSO HEMOPROTEINS, MYOGLOBIN
SEE ALSO PORPHYROPROTEINS, COBOGLOBINS
P60HL-16005-05 0013 Comprehensive sickle cell center ■
Study of regulation of erythropoiesis in vitro (human, rat,
hamster, rabbit)
ROlHL-20899-02 Cellular mechanisms of hemoglobin F
regulation (human)
ROlHL-20905-02 Synthesis of fetal hemoglobin in erythroid
cells (sheep, human)
ROlHL-20922-02 Control of human fetal hemoglobin
synthesis
ROlHL-24048-01 Regulation of hemoglobin synthesis in
chick embryos
GLOBULIN SUBSTANCE
SEE BLOOD COAGULATION, FACTOR VIM
GLOBULINS
SEE ALSO PLANTS PROTEINS, LECTINS, CONCANAVALIN A
ROlHL-08696-15 0012 Orthotopic heart transplantation -
Transplantation immunology-Modulation of donor
antigenicity (dogs)
ROlHL-15646 03 Lipid studies in vascular smooth muscle
cells (human, monkeys)
ROlHL-18762-03 Post-traumatic pulmonary insufficiency
(dogs)
ROlHL-194 19-03 Cellular interactions with foreign
materials (mammals)
ROlHL-214 52-02 Pulmonary capillary filtration in
myocardial ishemia (dogs)
GLOBUUNS, ALPHA GLOBULINS
SEE ALSO HEMOPROTEINS, HAPTOGLOBINS
SEE ALSO IMMUNOLOGY. IMMUNOREGULATORY ALPHA
GLOBULIN
SEE ALSO METALLOPROTEINS, CERULOPWSMIN
POlHL-03 174-23 0002 Mechanisms of acute vascular
reaction to injury • Chemical structure, pathological
significance of amyloid substance (human, mice)
GLOBULINS, BETA GLOBULINS
SEE ALSO GLOBULINS, MACROGLOBUUNS
SEE ALSO METALLOPROTEINS, TRANSFERRIN
ROlHL-19539-03 Pathology of hypertensive-associated
arteritis (rabbits)
P50HL 21006 02 0006 Sper.iali/id canlar ol rtiaixh in
arlarioiclerotit Inlravatrular roagulalion and Ihromboiii
in hyperlipidniniA (huiniiii)
GLOBUUNS, GAMMA GLOBULINS
SI I AlSUfaOHUIINS. MA(.MO(,IOBUIIN',
POIHI irilO 12 OUS'i Mechanl^mt ol laidiuvaicular
disease Blood and transluiion diu)fders (human, rati,
monkeys)
POIHL 15596 05 000/ Coagulation, librinolyiii,
hemostasis and hepatitis Structural ttudiet and
fractionation ol urokinase (human)
ROIHL 19651 03 Host factors in pathogenesis ol
respiratory disease (human, hamsters)
ROIHL 20856 02 Platelet transfusions Usage and
complications (human)
POIHL 22163 01 0001 Surface thrombogenesis
Mechanisms and prevention Initial blood protein and
platelet interactions with biomaterials (baboons)
GLOBULINS, GAAAMA GLOBULINS,
IMMUNOGLOBULIN(S)
SEE ALSO GLOBULINS. AMYLOID SUBSTANCE
SEE ALSO GLOBULINS. SERUM GLOBULINS
SEE ALSO IMMUNOLOGY. ANTIBODIES
P0IHL06314 17 Immunologic mechanisms in
cardiovascular disease
POIHL 06314 17 0048
cardiovascular disease
(rats, mice)
POIHL 06314 17 0050
cardiovascular disease
M
Immunologic mechanisms in
Pathogenesis of glomerulonephritis
'Excludes mutine methodok)gy OR covers only general projects which preclude indexing at the specific level.
•"Oriented significanthi to above subject.
M Grant has subpmjects descnbing specific research aspects.
See Appendix for investigator's name and grant numhpr
Immunologic mechanisms in
Physiologic changes in
lymphocytes (human, mice)
P01HL06314 17 0061 Immunologic mechanisms in
cardiovascular disease Role of viruses in cardiovascular
and renal disease (human, mice)
P01HL0637017 0018 Cardiopulmonary and renal
pathology research center Cytochemistry and immunology
of lymphoproliferative disorders (human)
R01HL07652 14 Destruction ol red blood cells in
hemolytic anemias (human, guinea pigs)
POlHL-07896-15 0021 Environmental biomedical research
program - Liquid breathing and lung lavage (human)
POIHL 08805-15 0049 Regulation of ventilation and
pulmonary circulation ■ Pulmonary hypertension produced
by Dirofilaria immitis in the dog
P01HL-0901MS 0001 A research and resource program
in blood - Genetic markers of human blood and gene
mapping (human)
POlHL-09011-15 0013 A research and resource program
in blood - A quantitative study of immunological
enhancement (mice)
ROlHL-09163-13 Control mechanisms in hemostasis
(human)
R01HL-10608-12 Digoxin-specific antibodies (human)
POIHLI 1310-12 0096 Mechanisms of cardiovascular
disease - Complement chemistry and biology (human.
rabbits)
ROlHL-12994-09 The Rh complex of red cells (human)
POlHL-13108-09 0003 Clinical heart transplantation -
Endomyocardial biopsy pathology
POlHL-13108-09 0013 Clinical heart transplantation -
Cardiomyopathic lymphocyte responsiveness to cultured
endothelium
POlHL-13262-07 0011 Arterial wall in atherosclerosis ■
Role of hypertension in atherosclerosis (human, monkey,
dog)
ROlHL-14799-07 Cardiac heterotransplantation-
Immunologic modification (mice, rat)
ROlHL-15124-05 Genesis of hypertension in renal disease
(human, dogs)
P01HL16137-05 0013 Alveolar biology - Development and
pathology of surfactant-Formation of alveolar (rabbits.
sheep)
POlHL-1641104 0003 Blood systems in coagulation and
vessel disease - Molecular events involving the late stages
of coagulation (rabbits)
POlHL-16748-05 0006 Cellular and immunological basis
of pulmonary diseases Sarcoidosis-Studies with bronchial
lavage (human)
POlHL-16769-05 0003 Pathobiologic and host defense
reactions in the lung - Pathobiologic mechanisms of
delayed sensitivity reactions in the lung (animals)
POlHL-16769-05 0011 Pathobiologic and host defense
reactions in the lung - Core-Laboratory for biomedical
preparation (rabbits)
P60HL- 17269-04 0033 National heart and blood vessel
research and demonstration center - Autoallergic response
in cardiomyopathy, atherosclerosis, rheumatic heart disease
ROlHL-17404-05 Immunologic mechanisms in heart
disease (mice)
ROlHL-17623-05 Initial events in thrombus formation on
surfaces (human, rats)
ROlHL-17710-04 Selective replication of hemoglobin genes
(mice, ducks, human)
POlHL-18646-03 0003 Studies basic to heart
transplantation - Host responses to xenografts (rodents.
rabbits)
POlHL-18646-03 0004 Studies basic to heart
transplantation - Presensitization-Detection. incidence and
clinical significance
(contd)
GLO
POlHL-18646-03 0006 Studies basic to heart
transplantation ■ Reduction or elimination of existing
presensitization (humane animals)
P01HL18827-02 0006 Platelet vessel wall interactions in
thrombogenesis - Platelet immune injury in man
R01HL18997-02 Ischemic therapy in experimental
hypersplenism (rats, dogs)
ROlHL-19018-03 Etiologic factors in cryptogenic fibrosing
alveolitis (human)
POlHL-19259-03 0002 Dlgoxinspecific antibody in human
therapy - Chemical semi-synthesis of digoxin-speciiic
antibody (rabbits)
ROlHL-1930703 Problems in prevention of rheumatic
heart disease (human)
** ROlHL-19456-03 Immunoglobulins associated with serum
hyperviscosity (human)
ROlHL'19628-03 Mechanisms of pulmonary alveolar
proteinoses (human, rats)
R01HL19873-03 Pulmonary responses to inhaled antigen
(rabbits, guinea pigs)
ROlHL-1998402 Blood pressure and immunogenetic
factors in the young (human)
ROlHL-20394-03 Complement activation by heart
subcellular membranes (human, dog)
ROlHL-20875-02 Chronic obstructive pulmonary disease -
Familial/genetic (human)
ROlHL-21829-01 Etiology of obstructive airway disease in
children (also monkeys)
ROlHL-22456-01 Lipoproteins In bioregulation of the
immune response (mice, human)
R23HL-22823-01 Phagocytic and immune defense
mechanisms of the lung (mice)
R23HL-2289501 Smoke inhalation -Biochemical and
cellular responses (rabbits, bacteria)
ROlHL-22924-01 The airway mucosal barrier (guinea pigs)
ROlHL-23631-01 Immunogenetic factors in allergic
respiratory diseases (human)
GLOBULINS, GAMMA GLOBULINS,
IMMUNOGLOBULIN A
SEE ALSO IMMUNOLOGY, SECRETORY (ANTIBODY) (FACTOR)
SYSTEM
P50HL-14218-07 0005 Pulmonary SCOR-Newborn lung
center - Prevention of infection in infants with respiratory
distress (human)
P50HL-15061-07 0007 Response of lung to injury -
Human factors for phagocytosis in normal and diseased
lungs
P50HL-15061-07 0009 Response of lung to injury ■
Alveolar macrophages (human, rabbits)
P50HL-1 5389-07 0010 Pulmonary SCOR-Hypersensitivity
pneumonitis - Clinical study-Pulmonary lesions due to non-
invasive aspergillosis
POlHL-16137-05 0001 Alveolar biology ■ Chemical
characterization of surfactant system-Lipid and lipid
protein fractions
POlHL-16769-05 0010 Pathobiologic and host defense
reactions in the lung - Bronchus associated lymphoid
tissue and delayed hypersensitivity (rabbits)
POlHL-1676905 0011 Pathobiologic and host defense
reactions in the lung ■ Core-Laboratory for biomedical
preparation (rabbits)
ROlHL-21565-02 Pathogenesis of inflammatory lung injury
(rats, rabbits)
GLOBULINS, GAMAAA GLOBULINS,
lAAMUNOGLOBULIN E
** R01HL01803-23 0021 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Induction of IgE antibodies to antigen
from tobacco and cigarette smoke (rabbits)
P50HL-14136-07 0003 Pulmonary SCOR-Airways
obstructive diseases - Acute pediatric respiratory disease
Pulmonary SCOR-Airways
Pediatric airways obstructive disease
and COLD
P50HL-14136-07 0017
obstructive diseases
(human)
P50HL14 153-07 0014 Johns Hopkins Lung Center-
Chronic diseases of airways - Mediator release in asthma
(human)
P50HL-14153-07 0015 Johns Hopkins Lung Center-
Chronic diseases of airways - Kinins and human lung
P50HL-15O92-07 0011 Immune and fibrotic response to
occupational environments - Respiratory and immunologic
responses in coffee plant workers
P50HL-1509207 0012 Immune and fibrotic response to
occupational environments - Longitudinal evaluation of
workers exposed to cotton dust
P50HL-15389-07 0001 Pulmonary SCOR-Hypersensitivity
pneumonitis - Clinical studies of hypersensitivity
pneumonitis
P50HL-15389-07 0010 Pulmonary SCOR-Hypersensitivity
pneumonitis Clinical study-Pulmonary lesions due to non-
invasive aspergillosis
P50HL-1538907 0011 Pulmonary SCOR-Hypersensitivity
pneumonitis - Animal model-Hypersensitivity pneumonitis
in rabbits
P50HL-1538907 0012 Pulmonary SCOR-Hypersensitivity
pneumonitis - Animal model-lmmunologic lung disease in
guinea pigs
P50HL-15389-07 0017 Pulmonary SCOR-Hypersensitivity
pneumonitis - Immunology core (human)
222
P50HL-1882803 0006 Specialized center of research in
thrombosis - Etiology and pathogenesis of atherosclerosis
(rabbit, monkey, rat, human)
P50HL-191 55-02 0004 Pathophysiology of pulmonary
edema - Physical and chemical effects of multiple
pulmonary emboli (sheep)
P50HL- 19 156-02 0004 Pulmonary SCOR-Chronic diseases
of airways - Interactions between mast cells, mediators
and nerves in canine asthma
P50HL19157-02 0008 Studies in cystic fibrosis and
bronchiolitis - Serum proteins in cystic fibrosis (human)
** P50HL191 57-02 0011 Studies in cystic fibrosis and
bronchiolitis - Pathogenesis of bronchiolitis (children)
P50HL-19171-02 0012 Pulmonary SCOR -Lung injury by
childhood infections - Laboratory support core
ROlHL-19741-03 Murine CRD -A model of chronic
pulmonary inflammation (mice, rats)
ROlHL-19777-03 Regulation of hypersensitivity in the lung
(rats, guinea pigs, rabbits, human)
R23HL-2 1089-02 Localization of mediators in dispersed
lung cells (guinea pigs, human)
ROlHL-21565-02 Pathogenesis of inflammatory lung injury
(rats, rabbits)
ROIHL'2241501 Mechanisms responsible for disease
severity In asthma (human)
ROlHL-22555-01 Structure and function of platelet
activating factor (rabbits, human)
** ROlHL-22582-01 Pulmonary and circulatory alterations
induced by IGE
GLOBULINS, GAMAAA GLOBULINS,
IMMUNOGLOBULIN G
ROlHL-08399-15 Platelet injury in infections and allergic
diseases (human)
R01HL12994-09 The Rh complex of red cells (human)
P50HL142 18-07 0005 Pulmonary SCOR-Newborn lung
center - Prevention of infection in infants with respiratory
distress (human)
P50HL-1423007 0096 A/S SCOR-Lipids. atherosclerosis
and thrombosis - Ultrastructural studies of endothelial cells
(human)
P50HL-15061-07 0007 Response of lung to injury ■
Human factors for phagocytosis in normal and diseased
lungs
P50HL-15061-07 0009 Response of lung to injury -
Alveolar macrophages (human, rabbits)
P50HL15389-07 0001 Pulmonary SCOR-Hypersensitivity
pneumonitis - Clinical studies of hypersensitivity
pneumonitis
P50HL15389-07 0010 Pulmonary SCOR-Hypersensitivity
pneumonitis • Clinical study-Pulmonary lesions due to non-
invasive aspergillosis
R01HL16601-05
(human, cattle)
Structure and function of blood proteins
Pathobiology of thromboembolic disorders
Bronchopulmonary resistance to bacterial
R01HL16646-05
(human)
ROlHL-16757-04 'Autoimmune' thrombocytopenia (monkey)
P50HL1915702 0011 Studies in cystic fibrosis and
bronchiolitis - Pathogenesis of bronchiolitis (children)
ROlHL-19721-03 Lung inflammation-Lysosomal proteases
and liposomes (human, rabbits)
ROlHL-20635-03 Factors in lung development (rat and
chick embryo)
P60HL-20985-01 0007 Northern California sickle cell
center • Immunohematologic abnormalities in sickle cell
anemia (human)
ROlHL-21565-02 Pathogenesis of inflammatory lung injury
(rats, rabbits)
ROlHL-22029-02
infection (mice)
** ROlHL-2230201 Immune responses in the human lung
(also rabbits, monkeys)
ROlHL-22671-01 Removal of senescent and stored human
red cells
NOlHV-32917-08 Materials development and testing
GLOBULINS, GAAAMA GLOBULINS,
IMMUNOGLOBULIN M
P50HL-142 18-07 0005 Pulmonary SCOR-Newborn lung
center - Prevention of infection in infants with respiratory
distress (human)
P50HL15389-07 0010 Pulmonary SCOR -Hypersensitivity
pneumonitis - Clinical study-Pulmonary lesions due to non-
invasive aspergillosis
POlHL-16769-05 0011 Pathobiologic and host defense
reactions in the lung - Core-Laboratory for biomedical
preparation (rabbits)
ROlHL-18535-03 Epidemiology and course of viral
myopericarditis (human)
P50HL-19157-02 0011 Studies in cystic fibrosis and
bronchiolitis - Pathogenesis of bronchiolitis (children)
GLOBULINS, GAMMA GLOBULINS,
IMMUNOGLOBUUN STRUCTURE
P01HL08805-15 0049 Regulation of ventilation and
pulmonary circulation - Pulmonary hypertension produced
by Dirofilaria immitis in the dog
P50HL-15061-07 0007 Response of lung to injury -
Human factors for phagocytosis in normal and diseased
lungs
ROlHL-1662605 Studies of antibodies to antihemophilic
factors (human, rabbits)
GLU
POlHL-19259-03 0002 Digoxin-specific antibody in human
therapy - Chemical semi-synthesis of digoxin-specific
antibody (rabbits)
** ROIHL- 194 5603 Immunoglobulins associated with serum
hyperviscosity (human)
GLOBULINS, AMYLOID SUBSTANCE
** P01HL03174-23 0002 Mechanisms of acute vascular
reaction to injury • Chemical structure, pathological
significance of amyloid substance (human, mice)
P01HL03174-23 0006 Mechanisms of acute vascular
reaction to injury - Atherosclerotic plaque studies using
mosaic analysis (human)
GLOBULINS, CORTICOSTEROID BINDING
GLOBULIN
SEE ALSO ADRENAL CORTEX HORMONES
ROlHL-21 112-02 Aldosterone binding, clearance, and
secretion in man
GLOBULINS, CRYOGLOBULINS
POlHL-06314-17 0050 Immunologic mechanisms in
cardiovascular disease - Physiologic changes in
lymphocytes (human, mice)
ROlHL-19456-03 Immunoglobulins associated with serum
hyperviscosity (human)
GLOBULINS, MACROGLOBULINS
SEE ALSO GLOBULINS, BETA GLOBULINS
SEE ALSO GLOBULINS, GAMMA GLOBULINS
R01HL04366-19 Plasminogen-Activatlon and structure-
function relations (mammals, birds)
P50HL-18828-03 0001 Specialized center of research in
thrombosis - Membrane biology and hemostasis (human)
P50HL-18828-03 0003 Specialized center of research in
thrombosis - Structure and function of plasma coagulation
inhibitors (human)
P50HL-18828-03 0006 Specialized center of research in
thrombosis Etiology and pathogenesis of atherosclerosis
(rabbit, monkey, rat, human)
POlHL-20994-02 0005 Dynamics of neutrophil elastase in
the lung - Protease inhibitors in pulmonary inflammation
and emphysema (rabbits)
ROlHL-21 12002 Membrane dynamics in alveolar
macrophages (rabbits)
ROlHL-21644-01 Fibronectin and related glycopiDtetns
(human, rodents)
GLOBULINS, MYELOMA GLOBULINS, BENCE-
JONES PROTEINS
R01HL-16e03-05 Human and experimental renal diseases
(animals)
GLOBULINS, SERUM GLOBULINS
SEE ALSO GLOBULINS, GAMMA GLOBULINS.
IMMUNOGLOBULIN(S)
SEE ALSO IMMUNOLOGY, ANTIBODIES, IMMUNE SERA
P01HL-15832-06 0008 Chemical-structural predispositions
to lung injury - Interstitial fibrosis-Connective tissue
components in normal and diseased lungs
GLOMERULAR FILTRATION
SEE KIDNEY FUNCTION, GLOMERULAR FILTRATION
GLOMERULONEPHRITIS
SEE KIDNEY DISORDERS. GLOMERULONEPHRITIS
GLOMERULOSCLEROSIS
SEE KIDNEY DISORDERS, NEPHROSCLEROSIS
GLOMERULUS
SEE KIDNEY, GLOMERULUS
GLOMUS AORTICUM
SEE NERVOUS SYSTEM, PARAGANGLIA, AORTIC BODY
GLOMUS CAROTICUM
SEE NERVOUS SYSTEM, PARAGANGLIA. CAROTID BODY
GLUCAGON
SEE PANCREAS HORMONES, GLUCAGON
1 ,4-ALPHA-D-GLUCAN :ORTHOPHOSPH ATE
ALPHA-GLUCOSYLTRANSFERASE
SEE GLYCOSYLTRANSFERASES, 1,4-ALPHA-D-
GLUCANtORTHOPHOSPHATE ALPHA-
GLUCOSYLTRANSFERASE
GLUCOCORTICOIDS
SEE ADRENAL CORTEX HORMONES, GLUCOCORTICOIDS
GLUCOGENESIS
SEE HEXOSES, GLUCOGENESIS
GLUCONEOGENESIS
SEE HEXOSES, GLUCONEOGENESIS
ALPHA-D-GLUCOPYRANOSYL-BETA-D-
FRUCTOFURANOSIDE
SEE DISACCHARIDES, SUCROSE
GLUCOSAMINE
SEE HEXOSES. GLUCOSAMINE
GLUCOSAMINOGLYCANS
SEE POLYSACCHARIDES. GLYCOSAMINOGLYCANS
(contd)
•Excludes routine melhodokigy OR covers only general projects which preclude indexing at the specific level.
**Onented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
3»S
OIU
OLUCOSf
SK H[XOSES. GLUCOSE
OLUCOSE, BLOOD
Sit CARBOHYDKATE BALANCE, BLOOD SUGAR
0-OLUCOSE
SEE HEXOSES, GLUCOSE
OLUCOSE BIOSYNTHESIS
SEE HEXOSES, GLUCOGENESIS
GLUCOSE BIOSYNTHESIS FROM NON-
CARBOHDRATE SOURCES
SEE HEXOSES. GLUCONEOGENESIS
GLUCOSE METABOLISM
SEE CARBOHYDRATES METABOLISM. GLUCOSE METABOLISM
GLUCOSE OXIDASE
SEE OXIDOREDUCTASES. GLUCOSE OXIDASE
GLUCOSE PERMEASES
SEE BIOLOGICAL TRANSPORT. TRANSPORT PROTEINS.
PERMEASES, GLUCOSE PERMEASES
GLUCOSE-6-PHOSPHATASE DEFICIENCY
SEE METABOLIC DISORDERS INBORN. GLYCOGENOSIS
GLUCOSE-6-PHOSPHATASES
SEE PHOSPHOMONOESTERASES. GLUCOSE 6 PHOSPHATASES
GLUCOSE-6-PHOSPHATE DEHYDROGENASE
SEE OXIDOREDUCTASES. GLUCOSE 6PH0SPHATE
DEHYDROGENASE
GLUCOSE-6-PHOSPHATE DEHYDROGENASE
DEFICIENCY
SEE METABOLIC DISORDERS INBORN. GLUCOSE 6 PHOSPHATE
DEHYDROGENASE DEFICIENCY
GLUCOSE-6-PHOSPHATES
SEE HEXOSES, GLUCOSE 6PH0SPHATES
GLUCOSE TOLERANCE
SEE CARBOHYDRATE BALANCE, GLUCOSE TOLERANCE
GLUCOSE TRANSPORT
SEE CARBOHYDRATES TRANSPORT. GLUCOSE TRANSPORT
ALPHA-GLUCOSIDASE
SEE CARBOHYDRASES. ALPHA-GLUCOSIDASE
GLUCURONIC ACID
SEE SUGAR ACIDS. HEXURONIC ACIDS, GLUCURONIC ACID
BETA-GLUCURONIDASE
SEE CARBOHYDRASES, BETA-GLUCURONIOASE
GLUTAAAATE-ALANINE TRANSAMINASE
SEE AMINOTRANSFERASES. ALANINE TRANSAMINASE
L-GLUTAMATE:AMMONIA LIGASE (ADP)
SEE ACID-AMMONIA LIGASES. L-GLUTAMATE:AMMONIA LIGASE
(ADP)
GLUTAAAATE-ASPARTATE TRANSAMINASE
SEE AMINOTRANSFERASES, ASPARTATE TRANSAMINASE
GLUTAAAATES
SEE DICARBOXYLIC AMINO ACIDS, GLUTAMATES
GLUTAMIC-OXALACETIC TRANSAAAINASE
SEE AMINOTRANSFERASES, ASPARTATE TRANSAMINASE
GLUTAMIC-PYRUVIC TRANSAMINASE
SEE AMINOTRANSFERASES. ALANINE TRANSAMINASE
GLUTAMINE
SEE DICARBOXYLIC AMINO ACIDS. GLUTAMINE
GLUTAMINE SYNTHETASE
SEE ACID-AMMONIA LIGASES. L-GLUTAMATE:AMMONIA LIGASE
(ADP)
GLUTAMYL CYCLOTRANSFERASE
SEE PROTEASES AND PEPTIDASES. GLUTAMYL
CYCLOTRANSFERASE
GLUTAMYL PEPTIDES
SEE PEPTIDES. HOMOPEPTIDES. GLUTAMYL
GLUTAMYL TRANSPEPTIDASE
SEE PROTEASES AND PEPTIDASES. GLUTAMYL
TRANSPEPTIDASE
GLUTATHIONE
SEE PEPTIDES. GLUTATHIONE
GLUTATHIONE PEROXIDASE
SEE PEROXIDASES. GLUTATHIONE PEROXIDASE
GLUTATHIONE REDUCTASE
SEE OXIDOREDUCTASES, GLUTATHIONE REDUCTASE
GLYCERALDEHYDE
SEE TRIOSES, GLYCERALDEHYDE
223
GLYCERALDEHYDE PHOSPHATE
DEHYDROGENASE
Sll DXIODRimiriASIS GIYCI RAID! HYDE PHOSPHATE
niHYIIRIK'.INASI
GLYCERIC ACID DIPHOSPHATES
Si I TRIOSE ACIDS, GLYCERIC ACID DIPHOSPHATES
GLYCERIDES
SEE LIPIDS. GLYCERIDES
GLYCERIN
SEE TRIOSE ALCOHOLS. GLYCERIN
GLYCEROL
SEE TRIOSE ALCOHOLS, GLYCERIN
GLYCEROL ESTERS
SEE LIPIDS, GLYCERIDES
GLYCEROL ETHERS
SEE LIPIDS. GLYCERYL ETHERS
GLYCEROPHOSPHATE DEHYDROGENASE
SEE OXIDOREDUCTASES. GLYCEROPHOSPHATE
DEHYDROGENASE
GLYCEROPHOSPHATES
SEE TRIOSE ALCOHOLS. GLYCEROPHOSPHATES
GLYCERYL ETHERS
SEE LIPIDS. GLYCERYL ETHERS
GLYCERYL PHOSPHATES
SEE TRIOSE ALCOHOLS. GLYCEROPHOSPHATES
GLYCERYLPHOSPHORYLCHOLINE
SEE PHOSPHOLIPIDS. GLYCEROPHOSPHORIC ESTERS,
GLYCEROPHOSPHORYLCHOLINE
GLYCINE
SEE AMINO ACIDS, GLYCINE
GLYCOGEN
SEE HEXOSANS, GLUCANS, GLYCOGEN
GLYCOGEN CATABOLISM
SEE HEXOSANS, GLUCANS, GLYCOGENOLYSIS
GLYCOGEN STORAGE DISEASE
SEE METABOLIC DISORDERS INBORN, GLYCOGENOSIS
GLYCOGEN (STARCH) SYNTHASE
SEE GLYCOSYLTRANSFERASES, UDP GLUC0SE:ALPHA-1,4-
GLUCAN ALPHA 4-GLUCOSYLTRANSFERASE
GLYCOGEN ESIS
SEE CARBOHYDRATES BIOSYNTHESIS
GLYCOGENOLYSIS
SEE HEXOSANS, GLUCANS, GLYCOGENOLYSIS
GLYCOGENOSIS
SEE METABOLIC DISORDERS INBORN, GLYCOGENOSIS
GLYCOGENOSIS TYPE III
SEE METABOLIC DISORDERS INBORN, GLYCOGENOSIS. TYPE
III
GLYCOLATES
SEE FAHY ACIDS, GLYCOLATES
GLYCOLIPIDS
SEE ALSO GLYCOSPHINGOLIPIDS
SEE ALSO PHOSPHOLIPIDS, PHOSPHOGLYCERIDES,
PHOSPHOINOSITIDES
NOlHI-32926-10 Analysis of lipoproteins (animals)
R01HL'053S1-18 Blood group antigens and antibodies
(human, rabbits, sheep)
ROlHL-17783-04 Complex carbohydrates-Structure,
function, synthesis (swine)
ROlHL-17898-03 Cell membranes and plasma lipoproteins
(human, swine)
ROlHL-18249-04 Isolation and identification of platelet
membrane (human)
ROlHL-20924-02 Atherosclerosis and arterial cell functions
(human, rabbits)
P01HL-22e33-01 0003 Cellular and molecular biology of
lipoprotein metabolism - Sterol metabolism in platelets and
megakaryocytes (human, rabbits, guinea pigs)
GLYCOLS
SEE ALCOHOLS, DIOLS
GLYCOLYSIS
SEE HEXOSES, GLYCOLYSIS
GLYCOLYSIS ANAEROBIC
SEE HEXOSES, GLYCOLYSIS ANAEROBIC
GLYCONEOGENESIS
SEE CARBOHYDRATES BIOSYNTHESIS. GLYCONEOGENESIS
GLYCOPEPTIDES
SEE ALSO GLYCOPROTEINS
ROlHL-14844-06 Mucous glycoprotein in human respiratory
epithelium (also wheat)
ROlHL-19084-03 Structure and function of serum
lipoproteins (human)
OlY
RUIHI /Ibl/U^ bioihimittry ul lung iirul«u|hr'>nt
(human, iibbilt)
ROIHI Ti'Mi 07 Ultriitruclural itutfy ol •ndothtliuin in
thromboiit (human)
ROIHI 22967 01 Struclura and lunilion of hapaiin
relratabla lipaui (iwine, human)
GLYCOPROTEINS
SEE Also CARBOHYDRAIES, PROTEIN BOUND
CARBOHYDRATES
SEE Also GlYCOPEPTIOES
SEE AISOPROTEOCIYCANS
ROIHI 01803 23 0001 Arleriotclerosit. (lomerulonephrrtii,
rheumatic lever Post streptococcal ilomerulonephritn
(rabbit)
ROIHL 01803 23 0011 Arteriosclerosis, glomerulonephritis.
rheumatic fever Immunopathologic consequences of
cigarette smoking (human, rabbits, plants)
•* R01HL01803 23 0022 Arteriosclerosis, glomerulonephritis,
rheumatic fever Cardiac and pulmonary anaphylaxis
induced by tobacco glycoprotein (rabbits)
ROIHL 02942 22 Biochemistry of cardiovascular connective
tissue (human, cattle, primates)
ROIHL 0S3SI 18 Blood group antigens and antibodies
(human, rabbits, sheep)
POIHL 0631417 0064 Immunologic mechanisms in
cardiovascular disease Diabetic vascular disease (human.
rats, mice)
POIHL 09011 15 OOOS A research and resource program
in blood Characterization of hepatitis 6 antigen and the
cause of serum hepatitis (human)
ROIHL 09739 13 Biophysical studies of proteins (human)
ROIHL 1031613 Structural studies on low density serum
lipoproteins (human)
POIHL 11310 12 0097 Mechanisms of cardiovascular
disease Structural-functional relationships of neuronal
differential alloantigens (mice)
** P01HL-113I0 12 0098 Mechanisms of cardiovascular
disease Protein chemistry of thyl and related
synaptosomal proteins (mice)
'* POIHL 11310 12 0099 Mechanisms of cardiovascular
disease - Carbohydrate chemistry of thy 1 and related
synaptosomal proteins
** POlHL-1131012 0105 Mechanisms of cardiovascular
disease Biosynthesis of mammalian glycoproteins
(rabbits)
POlHL-1135112 0004 Cellular and molecular
mechanisms of myocardial function - Molecular
mechanisms of contractile function and differentiation
(animals)
ROlHL-11511-10 Structure of ferritin and its role in iron
metabolism (horse, rats, human)
POlHL-13262-07 0012 Arterial wall in atherosclerosis -
Characterization of connective tissue components (animals)
R01HL-I3336-09 Biochemistry and physiology of human
platelets
ROIHL- 1383 1-08 Factors regulating embryonic cardiac
morphogenesis (chick, salamandra)
ROlHL-13885-08 0009 Cystic fibrosis and pulmonary
disease - Respiratory mucus glycoproteins (human, rabbits)
P50HL- 142 17-08 0054 Specialized center of research in
thrombosis - Coagulation section -Platelet aggregation
(human, pig, rabbit, dog)
ROlHL-14313-07 Apoproteins of triglyceride rich
lipoproteins (human, squirrel monkeys, rats)
R01HL-14692-06 Alpha 1 antitrypsin deficiency and
pulmonary disease (human)
ROlHL-14697-07 Role of platelet membranes in
hemostasis (human)
** ROlHL-14844-Oe Mucous glycoprotein in human respiratory
epithelium (also wheat)
P50HL-15103-07 0014 A/S SCOR -Early natural histoi> of
arteriosclerosis - Biochemistry of atherosclerotic lesions
(monkeys, human, cattle)
P50HL- 15389-07 0014 Pulmonary SCOR-Hypcrsensitivity
pneumonitis - Fractionation and characterization of pigeon
antigens
ROlHL-1547406 Structure and function of the
antihemophilic factor (human, cattle)
ROlHL-15615-06 Structure-function studies of human
factor Vlll/vWF
ROlHL-15616-04 Platelet membrane proteins in
aggregation (human)
** ROIHL 15728-06 The carbohydrate of the blood-clotting
glycoproteins (mammals)
POIHL- 15832-06 0001 Chemical-structural predispositions
to lung injury - Chemical composition of lung connective
tissue proteins (human, animals)
POlHL-15832-06 0008 Chemical-structural predispositions
to lung injury - Interstitial fibrosis-Connective tissue
components in normal and diseased lungs
ROlHL-15958-06
and neurotoxin
R01HL16318-21
transport
ROlHL-17194-03 Comparison of two inherited forms of
alpha-1-antitrypsin (human)
P60HL-17269-04 0017 National heart and blood vessel
research and demonstration center - Cell membrane (dogs,
rabbits)
ROlHL-17623-05 Initial events in thrombus formation on
surfaces (human, rats)
(contd)
X-ray diffraction analysis of thrombin
Biochemistry and pharmacology of Na-K
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
**0iieflte4 significantly to atxwe subject.
M Grant has subprojects descnbing specific research aspects.
See Appendix for Investigator's name and grant number.
GLY
ROlHL-17783-04 Complex carbohydrates-Structure,
function, synthesis (swine)
P01HL17812-04 0005 Thrombosis and plasma proteins
In vitro systems of normal platelets, white cells, sera
(human)
ROlHL-17881-15 Biosynthesis and degradation of blood
group substances (human, animals)
Cell membranes and plasma lipoproteins
Comprehensive studies of mucociliaiy
ROlHL-17898-03
(human, swine)
ROlHL-18308-03
transport (dogs)
ROlHL-18553'03 Membrane defects in familial
hypercholesteremia (human)
R01HL18634-03 Quarternary structure of erythro and
chlorocruorins (invertebrates)
P01HL18645-03 0003 Biology of the artery wall and
atherosclerosis - Synthesis of connective tissue proteins by
smooth muscle cells (human, monkeys)
ROlHL-187 14-04 Cardiovascular matrix -Morphogenesis
and maturation (human, chick embryo, mammal)
P50HL-18828-03 0001 Specialized center of research In
thrombosis - Membrane biology and hemostasis (human)
P50HL- 18828-03 0002 Specialized center of research in
thrombosis - Endothelial cell biology (human, guinea pig)
P50HL-18828-03 0006 Specialized center of research in
thrombosis - Etiology and pathogenesis of atherosclerosis
(rabbit, monkey, rat, human)
ROIHL 18931-02 Lung elastic tissue characteristics
(swine, human)
ROlHL-19011-03 Smooth muscle cell membrane
glycoprotein biosynthesis (cattle)
ROlHL-19056-03 Blood triglycerides and lipoprotein lipase
in the lung (rats)
ROIHL- 19068-03 Changes in membrane properties during
erythropoiesis (chick embryo)
P50HL-19160-02 0001 Mucus abnormality in cystic
fibrosis - Regulation of respiratory secretions (rat, human)
ROlHL-19175-03 Pituitary modulation of micro-and macro-
vascular disease (human, rats)
' P50HL19190-02 0005 Pulmonary SCOR-Pathophysiology,
management of IRDS - Glycoproteins In mucous secretions
(human, cattle)
ROlHL-19279-03 Intracellular action of aldosterone in
hypertension (human, rats)
ROlHL-19685-03 Pathogenesis of inflammation of the lung
(guinea pigs)
' ROIHL- 19996-02 Role of membrane proteins in platelet
function (human, rabbits)
ROlHL-2007002 Alphalantitrypsin deficiency (human,
hamsters)
' ROlHL-20140-02 Glycoproteins of platelet membrane and
platelet function (human)
ROlHL-20426-03 Myocardial function in diabetes mellltus
(dog, rat)
* ROlHL-20471-03
(human)
ROlHL-20520-03 Protein modification -The key to diabetic
sequelae (human, animal)
ROlHL-20533-09 Pathogenesis of rheumatic fever (human,
rabbits)
* ROlHL-20547-02 Glycoproteins in pulmonary alveolar
proteinosis (human)
ROlHL-2081802 Platelet storage at 22 degrees C
(human)
* ROlHL-20868-02
lung (swine)
* ROlHL-20971-10 Membrane glycoproteins of platelets and
leukocytes (human)
R23HL-21369-02 Tracheal mucin synthesis in experimental
bronchitis (rats)
ROlHL-21394-02
(rabbits)
ROlHL-21404-01 Raman spectroscopy of erythrocyte and
model membranes (human)
* ROlHL-21480-01 Structure, source and functions of
alveolar glycoproteins (human, rabbits)
ROlHL-21487-01 Molecular characterization of
Glanzmann's thrombasthenia (human)
* ROlHL-21644-01 Fibronectin and related glycoproteins
(human, rodents)
* ROlHL-2168302
ROlHL-21686-02
* ROlHL-21701-02
* ROlHL-22270-01
ROlHL-22444-01
culture (human)
R01HL-22583-02
thrombosis (human)
P01HL-22602-01 0001 Pathophysiology of the
endothelium • Platelet-endothelial interactions in vitro
(human, cattle)
POlHL-22633-01 0003 Cellular and molecular biology of
lipoprotein metabolism - Sterol metabolism in platelets and
megakaryocytes (human, rabbits, guinea pigs)
'* R23HL-22818-01 Biosynthesis of human respiratory
mucous glycoprotein (also dog)
ROlHL-23588-01 NOV infection -Analysis at the subcellular
level (chickens)
ROlHL-23595-01 Experimental emphysema -Depression of
protease inhibitors (rats, hamsters)
ROlHL-2394506 Pathologic effects on cells of modified
lipoproteins (rats, human)
Atherosclerosis and diabetes mellltus
Regulation of glycoprotein biosynthesis in
Pulmonary angiotensin-converting enzyme
Purification of erythropoietin (human)
Purification of erythropoietin (human)
Purification of erythropoietin (human)
Platelet glycoprotein (human)
Bronchial mucus production in organ
Ultrastructural study of endothelium in
224
** NOlHR-52957-02 Composition of respiratory mucus
(human, swine)
GLYCOSAAAINOGLYCANS
SEE POLYSACCHARIDES, GLYCOSAMINOGLYCANS
GLYCOSIDASES
SEE CARBOHYDRASES
GLYCOSIDE HYDROLASES
SEE CARBOHYDRASES
GLYCOSIDES
SEE CARBOHYDRATES. GLYCOSIDES
GLYCOSPH INGOUPIDS
*' R01HL17462-03 Role of glycosphingolipids in platelet
aggregation (rats, human, dogs)
ROlHL-17898-03 Cell membranes and plasma lipoproteins
(human, swine)
R01HL18249-04 Isolation and identification of platelet
membrane (human)
POlHL-18577-03 0001 Lipoproteins- Cell surface
interactions - Structural studies of serum lipoproteins in
man and dogs
GLYCOSPHINGOLIPIDS, CERAMIDE DIHEXOSIDES
ROlHL-17462-03 Role of glycosphingolipids in platelet
aggregation (rats, human, dogs)
GLYCOSPH INGOUPIDS, CERAAAIDE
TRIHEXOSIDES
ROlHL-1746203 Role of glycosphingolipids in platelet
aggregation (rats, human, dogs)
N-GLYCOSYLHYDROLASES
R01HL17783-04 Complex carbohydrates-Structure,
function, synthesis (swine)
N-GLYCOSYLHYDROLASES, NAD NUCLEOSIDASE
POlHL-063 14-17 0057 Immunologic mechanisms in
cardiovascular disease - Antigens in cardiovascular disease
(human)
GLYCOSYLTRANSFERASES
** POlHL-11310-12 0105 Mechanisms of cardiovascular
disease - Biosynthesis of mammalian glycoproteins
(rabbits)
ROlHL-14697-07 Role of platelet membranes in
hemostasis (human)
ROlHL-1512507 Molecular pathology of genetic disorders
in nun
** ROlHL-17462-03 Role of glycosphingolipids in platelet
aggregation (rats, human, dogs)
ROlHL-17623-05 Initial events in thrombus formation on
surfaces (human, rats)
ROIHL- 177 83-04 Complex carbohydrates-Structure,
function, synthesis (swine)
*• R01HL-20301-02 Genetics of glycosyltransferases in
human blood
ROlHL-20868-02 Regulation of glycoprotein biosynthesis in
lung (swine)
R23HL-228 18-01 Biosynthesis of human respiratory
mucous glycoprotein (also dog)
NOlHR-72921-01 Cystic fibrosis factor identification and
quantification (human)
GLYCOSYLTRANSFERASES, ADENINE
PHOSPH ORIBOSYLTRANSFERASE
ROlHL-14730-07 Fatty acid beta-oxidation in normal and
ischemic hearts (rabbits)
GLYCOSYLTRANSFERASES,
GALACTOSYLTRANSFERASES
ROlHL-151 25-07 Molecular pathology of genetic disorders
in man
ROlHL-23595-01 Experimental emphysema-Depression of
protease inhibitors (rats, hamsters)
GLYCOSYLTRANSFERASES, 1,4-ALPHA-D-
GLUCAN:ORTHOPHOSPHATE ALPHA-
GLUCOSYLTRANSFERASE
POlHL-0821415 0023 Chemical and biological properties
of lipids - Lipids in microorganisms and cell cultures
(hamsters, mosquitoes)
ROlHL-10384-13 Blood flow and nucleotide metabolism
(animals)
ROlHL-19181-02 Regulation of heart cAMPdependent
protein kinase (rodents)
R23HL-21320-02 Cyclic nucleotide metabolism in vascular
endothelium
GLYCOSYLTRANSFERASES, IMP:PYROPHOSPHATE
PHOSPHORIBOSYLTRANSFERASE
R01HL15125-07 Molecular pathology of genetic disorders
in man
GLYCOSYLTRANSFERASES, UDP
GLUCOSE:ALPHA-1 ,4-GLUCAN ALPHA-4-
GLUCOSYLTRANSFERASE
POlHL-082 14-15 0023 Chemical and biological properties
of lipids - Lipids in microorganisms and cell cultures
(hamsters, mosquitoes)
POlHL-12373-10 0012 Cardiopulmonary physiology and
pathophysiology - Biochemistry of the sympathetic nervous
system (rats, rabbits, pigeons)
ROIHL- 13630-08
(cattle)
ROlHL-22064-02
myocardium (rats)
GRO
Control of glycogen synthesis in heart
Glycogen metabolism In anoxic diabetic
GLYOXALASE I
SEE CARBON-SULFUR LYASES, GLYOXAUSE I
GMP
SEE PURINE NUCLEOTIDES, GUANINE NUCLEOTIDES. GMP
GMP CYCLIC
SEE PURINE NUCLEOTIDES. GUANINE NUCLEOTIDES. GMP
CYCLIC
GOAL-STRIVING BEHAVIOR
SEE PSYCHOLOGY, BEHAVIOR, GOAL-STRIVING
GOATS
SEE MAMMALS, ARTIODACTYU, GOATS*
GOLGI APPARATUS
SEE CELL COMPONENTS. GOLGI APPARATUS
GONADOTROPINS CHORIONIC
SEE REPRODUCTIVE HORMONES. GONADOTROPINS
CHORIONIC
GONADS
SEE REPRODUCTIVE SYSTEM, GONADS
GOODPASTURE'S SYNDROME
SEE DISEASES, SYNDROMES NOT LISTED ELSEV^HERE,
GOODPASTURE'S SYNDROME
GORETEX
SEE PLASTICS. FLUOROCARBON POLYMERS
GOUT
SEE PURINESPYRIMIDINES METABOLISM ERRORS, GOUT
GOUT DRUGS
SEE PURINESPYRIMIDINES METABOLISM ERRORS, GOUT
DRUGS
GRAFTS
SEE TISSUE COMPATIBILITY-TRANSPLANT. TRANSPUNTATION
GRAM-NEGATIVE AEROBIC RODS AND COCCI
SEE BACTERIA, HALOBACTERIACEAE*
GRAM-NEGATIVE BACTERIA
SEE BACTERIA. GRAM-NEGATIVE*
GRAMICIDIN
SEE ANTIBIOTICS. GRAMICIDIN (UNSPECIFIED)
GRANULOCYTES (GENERAL)
SEE BLOOD CELLS. LEUKOCYTES, GRANULOCYTES (GENERAL)
GRANULOCYTIC LEUKEMIA
SEE NEOPLASMS OF BLOOD AND RE SYSTEM. LEUKEMIA
MYELOID
GRANULOCYTOPENIA
SEE BLOOD AND RE DISORDERS. LEUKOCYTE DISORDERS.
AGRANULOCYTOSIS
GRANULOMA
SEE NEOPLASMS REWTED INTEREST. GRANULOMA
GRANULOMA, HODGKIN'S
SEE NEOPUSMS OF BLOOD AND RE SYSTEM. HODGKIN'S
DISEASE
GRANULOMA AND FIBROSIS, PULMONARY
SEE RESPIRATORY DISORDERS. PULMONARY FIBROSIS AND
GRANULOMAS
GRAPHITE
SEE CARBON
GRAVITY
SEE ENVIRONMENT. GRAVITY-MOTION
GRAYANOTOXINS
SEE TOXICOLOGY, PUNT POISONS, GRAYANOTOXINS
GROUND SUBSTANCE
SEE CONNECTIVE TISSUE, GROUND SUBSTANCE
GROUP COUNSELING (PSYCHOLOGY)
SEE MENTAL HEALTH SERVICES, COUNSELING, GROUP
GROUP PROCESSES
SEE PSYCHOLOGY SOCIAL. GROUP PROCESSES
GROUP THERAPY
SEE PSYCHOTHERAPY. GROUP THERAPY
GROUPS, SOCIAL
SEE SOCIAL GROUPS
GROWTH ABNORMAL, HYPERPLASIA (GENERAL)
SEE ALSO BLOOD AND RE DISORDERS, LEUKOCYTE
DISORDERS, LEUKOCYTOSIS
SEE ALSO CONNECTIVE TISSUE HYPERPLASIA
SEE ALSO NEOPUSMS OF BLOOD AND RE SYSTEM, BONE
MARROW NEOPUSMS, MYELOPROLIFERATIVE
R01HL-0298e-21 Zonal renal change with potassium
deficiency (rats, human)
(contd)
•Excludes routine methodology OR covers only general projects which preclude i
"Oriented significantly to above subject.
ndexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
ORO
ROIHL 1265008 Envlronmanlil pathobioloiv ot tha lunR
(hamslets. fits)
ROIHL 17322 04 Functional characteristics of smooth
muscle Isolated from lung (animals)
POIHI I8S7S 03 0007 Mechanisms ot vascular changes
In hypertension Microscopy ot hypertensive arterial lesions
(tats)
•* POIHL 20b92 02 0010 Cell biology ot cardiac and
skeletal muscle Mitochondrial genesis during myocardial
cell hypertrophy and hyperplasia (rats)
ROIHI 22859 01 Ellect ol carbon monoxide on the
developing heart (rats)
ROIHI 23600 01 Ions. y«ater. and hypertension (human,
dogs, rats)
GROWTH ABNORA^L, HYPERTROPHY
SEE ALSO BLOOD AND RE DISORDERS, SPLENIC DISORDERS.
SPLENOMEGALY
SEE ALSO HEART DISORDERS. HEART ENLARGEMENT,
VENTRICUUR HYPERTROPHY
SEE ALSO KIDNEY DISORDERS. RENAL HYPERTROPHY
** P01HL06285 18 0149 Cardiovascular respiratory
physiology and biochemistry Microangiopathy in
prediabetic and diabetic subjects (human)
** P01HL0628518 0150 Cardiovascularrespiratory
physiology and biochemistry Basement membrane width
in non-drabetic hyperglycemia
*• P01HL06285-18 0151 Cardiovascular respiratory
physiology and biochemistry Microangiopathy rn diabetic
and glucose intolerant children
PO1HL06285 18 0152 Cardiovascular-respiratory
physiology and biochemistry - Diabetic microangiopathy by
organ and tissue culture (human)
P01HL1130712 0003 Biophysical studies in pediatric
cardiology Cellular biophysics (animals)
ROIHL- 13636-08 Eftects ol pharmacologic agents on heart
metabolism (human, rodents)
POlHL-14388-07 0196 Regulation of the circulation in
pathological states - Altered vascular responsiveness in
spontaneous hypertension (rats)
POlHL-14388-07 0197 Regulation of the circulation in
pathological states - Altered vascular reactivity in
pathogenesis ol spontaneous hypertension (rats)
ROlHL-16606-11 Contraction in heart and other striated
muscles (frogs)
** ROlHL-19044-03 Effect of drugs on development of
cardiac failure (cats)
** ROlHL-22845-01 Response of cardiac myosin to
hypertrophic stress (rabbits)
ROlHL-22859-01 Effect of carbon monoxide on the
developing heart (rats)
** ROlHL-23210-01 Biology of normal and hypertrophied
pulmonary vessels (cat, human)
ROlHL-23232-01 Effect of hypoxia on PVSM and its
precursor cells
GROWTH ABNORAAAL, METAPLASIA
P50HL-19157-02 0002 Studies in cystic fibrosis and
bronchiolitis - Clinical core
GROWTH AND DEVELOPMENT
SEE ALSO BODY WEIGHT
SEE ALSO CELL DIVISION
SEE ALSO CELL GROWTH REGULATION
SEE ALSO CHILD DEVELOPMENT (NON-PSYCHOLOGICAL)
SEE ALSO NEOPLASTIC GROWTH
SEE ALSO POPULATION STUDIES CELL
" POlHL-06312-17 0018 Surgical cardiology - Cardiac
transplantation growth (calves)
** POlHL-07896-15 0060 Environmental biomedical research
program - Effect of pressure on development of marine
crustacean larvae
** POlHL-12157-11 0037 Functions and mechanisms of cell
membrane ion transport - Developing structure of heart
cells in tissue culture
** POlHL-12157-11 0055 Functions and mechanisms of cell
membrane ion transport - Growth and development of
synthetic strand heart cells in culture (chick embryo)
POlHL-12157-11 0057 Functions and mechanisms of cell
membrane ion transport - Electrophysiological
investigations of synthetic strands of heart muscles (rats)
" POlHL-12738-10 0134 Physiologic pharmacology and its
clinical applications - Adenylate cyclase and cAMP
phosphodiesterase in cardiac development (dogs)
** R01HL13237-09 Erythrocytes during early development
(human, animals)
ROlHL-13339-08 Pharmacology of developing cardiac
tissues (chick embryo)
** POlHL-14388-07 0193 Regulation of the circulation in
pathological states - Ontogenesis of central nervous system
amines in hypertension (rats)
POlHL-14580-07 0002 Program project in respiratory
mechanics - Airway aerodynamics (human, dogs)
ROlHL-14717-06 Hemodynamics and heart structure-
Ventricular overload (dogs)
POlHL-14985-07 0005 Adaptation to hypoxia - Control
mechanisms in the pulmonary microcirculation (animals)
ROlHL-15316-07 Lung surfactant system -Control
mechanisms (rats)
** ROlHL-15526-05 Respiratory mechanics in children
ROlHL-15655-05 Blood flow and gas exchange in placenta
and lungs (sheep) rabbits)
235
** ROIHL 16152 06 Electrophysiology ol neonatal to adult
heait (cats, frogs, guinea pigs)
M POIHI 16683 04 Function and growth ol cardiac and
skeletal muscle
" POIHI 16683 04 0001 Function and growth ol cardiac
and skeletal muscle Light chains of the skeletal and
cardiac myosin molecule (rabbits, tiogs)
•* POIHL 16683 04 0002 Function and growth ol cardiac
and skeletal muscle Myosin, actin, ATP, interaction in
solution
•* POIHL 16683 04 0003 Function and growth ol cardiac
and skeletal muscle Movements ol SI moieties In muscle
libers
** POIHL 1668304 0006 Function and growth of cardiac
and skeletal muscle Chemical studies ol the contractile
system Development of new reagents
** POIHL 16748 05 0004 Cellular and immunological basis
of pulmonary diseases Cellular and immunological
processes in pulmonary defense systems
** ROIHL 1736705 Functional sympathetic development In
neonatal hearts (dogs, human)
ROIHL 1762903 Developmental aspects of cardiovascular
function (human, cats, rabbits)
ROIHL 17800 04 Pulmonary reflexes Central pathways
(cats, dogs, rabbits)
** ROIHL 17993-04 0009 Ventricular dynamics from
surgically inserted markers - Cardiovascular visualization in
surgery ol growing heart (dogs)
ROIHL 18712-03 Iron deficiency-hypertipidemia in
development (rats)
ROlHL-190 10-03 Metabolism and cell biology of lung
surfactant system (rabbits, sheep)
P50HL-19185 02 0011 Pulmonary SCOR -Neonatal
respiratory distress syndromes - Complications and
sequelae of neonatal respiratory distress (human)
ROIHL 19225-02 0001 Types and mechanims of
pulmonary hypertension - Structural changes (human,
animals)
ROlHL-19225-02 0002 Types and mechanims of
pulmonary hypertension - Effect ol aorto-pulmonary shunt
(pigs)
ROlHL-19430-03 Congenital heart malformations and
situs inversus (mice)
POIHL 19717 02 0002 Response of the lung to injury ■
Prolyl hydroxylase, lysyl hydroxylase and lung collagen
biosynthesis (rabbits)
POlHL-197 17-02 0005 Response of the lung to injury -
Studies on proteolysis and lung disease (human, animals)
POlHL-19717-02 0006 Response of the lung to ir»jury -
Glycosaminoglycans and proteoglycans of the lung (human,
rats, hamsters)
** POlHL-19717-02 0028 Response of the lung to injury ■
Compensatory growth of the lung following pneumonectomy
(rabbits)
ROlHL-19752-03 Phospholipid synthesis by fetal lung in
organ culture (rats)
ROlHL-19858-03 UMMC-Blood pressure precursors and
consequences (human)
ROlHL-19864-03 0003 Blood pressure of children and
young adults Heart rate and blood pressure-Consistency
in infancy (human)
ROlHL-201 59-03 Genetic epidemiology of precursors of
hypertension (human)
** ROlHL-20344-02 Regulation ol protein turnover in lung
tissue (rats)
POlHL-20581-01 0002 Vascular neuroeffector
mechanisms in health and disease - Trophic interaction
between adrenergic nerves and vascular smooth muscle
ROlHL-20635-03 Factors in lung development (rat and
chick embryo)
** ROlHL-20749-01 Developing heart-Biophysical aspects
(sheep)
** ROlHL-20864-01 Postnatal maturation of cardiovascular
regulatory system (minipig)
R23HL-21225-02 Connective tissue precursor molecules in
the lung (rabbits, hamsters)
ROlHL-2 13 76-02 Blood-gas barrier solute and water
transport (rabbits)
ROlHL-21444-02 Pulmonary mechanics during postnatal
development (human)
ROlHL-22290-01 Cardiac energy metabolism and protein
synthesis (mice)
POlHL-22619-01 0007 Cellular mechanisms of heart
failure - Regulation of contractile protein levels in heart
muscle (rats)
ROIHL 22651-01 Control of protein metabolism in heart
muscle
** ROlHL-22664-01 Regulation of myocardial cell growth
(rats, guinea pigs)
R23HL-227 75-01 Muscarinic receptors in the developing
heart (chick embryo)
** ROlHL-23025-01 Adaptive heart growth in neonates and
adults (rats)
ROlHL-23601-01 Early hypoxia and development ol
respiratory control
GROWTH AND DEVELOPMENT, HISTOGENESIS
SEE ALSO CARDIOVASCULAR SYSTEM, ANGIOGENESIS
SEE ALSO CELL-CELL INTERACTION, CELL AGGREGATION
SEE ALSO CELL DIFFERENTIATION
SEE ALSO CONGENITAL ABNORMALITIES
SEE ALSO CONNECTIVE TISSUE DEVELOPMENT
SEE ALSO DENTAL DEVELOPMENT
'Excludes ruutine methodology OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojects describing specif!
See Appendix for investigator's name and
GRO
SEE ALSO MUSCIFS, MYOCFNFSIS
SEE AISONIKVOUS SYMIM NIUROGINISIS
Sf( Also PIIIJIIARY GIAND UlSORUtHS. ACROMEGALY
ROIHI 0/605 16 Congenitil heart diMase teMifCh
program (human, dogi)
POIHI 10436 13 0009 A multidisciplinary study ol
congenital heart dr.ease Palhophy.iology and
morphogenesis ol congenital heart diveave (human)
ROIHL 13901 08 Ontogeny, ulliaslrutlure. lunttion in
lymphatic system (bird^, (I'.h, mammals)
P50H( 14214 07 0015 Newborn lung center lor hyaline
membrane disease Hormone ellect on cyclic nucleotide
lipid synthesis in developing lung (animal)
** P50HL 14214 07 0020 Newborn lung center lor hyaline
membrane disease Epidermal growth factor ellect Lung
dillerentiation. maturation (human, rabbrt)
" P50HI 14214 07 0021 Newborn lung center lor hyaline
membrane disease Development of surfactant system
Surfactant production and release (rat. rabbit)
P50HL 14214 07 0022 Newborn lung center for hyaline
membrane disease Functional integrity ol surtaclant
system- Hyaline membrane disease (lamb, rat)
** P50HL 1421407 0023 Newborn lung center for hyaline
membrane disease Regulation of fetal lung maturation-
Vitamin A (rat. rabbit, sheep, human)
P50HL 14214 07 0024 Newborn lung center lor hyaline
membrane disease Synthesis and receptors lor ACTH In
letal lung (human)
ROIHL 1485407 Lung and tissue mechanics (monkeys,
dogs)
** ROIHL 15341-06 Lung hormonal and chromosomal
regulation (rats, rabbits)
ROlHL-15444 06 Neonatal development ol adrenergic
receptor mechanisms (pigs)
POlHL-16117-05 0001 Ion movements and membranes in
cardiovascular control Developmental studies of
contractile cell junctions (rats, rabbits, elasmobranch)
** POlHL-16137-05 0013 Alveolar biology Development and
pathology of surfactant-Formation ol alveolar (rabbits,
sheep)
P60HL 17269 04 0021 National heart and blood vessel
research and demonstration center - Grovrth and
development ol heart -Ultrastructure (dog, guinea pig. rat,
cat)
ROlHL-17719-03 Lung injury, substrate utilization, oxygen
toxicity (rats, rabbits, dogs)
POlHL-17731-04 0003 Physiological basis ol pulmonary
disease - Comparative physiology (vertebrates)
P50HL-19185-02 0001 Pulmonary SCOR-Neonatal
respiratory distress syndromes Sites ol synthesis,
secretion and structure of surface active material (rat)
P50HL-19185-02 0002 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Biochemistry,
ultrastructure-Pulmonary surface active material (human,
animal)
** P50HL-19185-02 0003 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Factors affecting formation
and release ol pulmonary surtactant in fetal lambs
♦* P50HL-19185-02 0005 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Role and mechanism of
glucocorticoids in fetal lung maturation (human, rabbit)
** ROlHL-19379-03 Characterization of small-granule cells in
the lung (mammals)
** POlHL-19717-02 0023 Response of the lung to injury -
Postna;al lung development -Cells, connective tissue and
physiology (animals)
** POlHL-19717-02 0024 Response of the lung to injury -
Formation of lung alveoli (rats)
** POlHL-19717-02 0025 Response of the lung to injury ■
Role of oxygen in regulation of lung growth and
development (rats)
** POlHL-19717-02 0026 Response of the lung to injury -
Protein depletion and postnatal lung development (rats)
** POlHL-19717-02 0027 Response of the lung to injury -
Hormone control of lung growth and development (rats)
** ROlHL-20132-03 Histogenesis and biochemistry of
embryonic lung (birds)
** ROlHL-20749-01 Developing heart-Biophysical aspects
(sheep)
ROlHL-21176-02 Phospholipid exchange proteins in lung
tissue (lambs)
ROlHL-21649-01 Biochemistry of lung proteoglycans
(mammals)
ROlHL-22560-02 Structure and motion of cilia
(Tetrahymena, mussels)
ROlHL-22784-01 Ductus arteriosus closure-An arterial
lesion model (rabbits)
** R23HL-22959-01 Heart development in inherited
cardiomyopathy (hamsters)
ROlHL-22963-01 Symbolic logic analysis of congenital
heart disease (human)
GROWTH AND DEVELOPMENT, REGENERATION
SEE ALSO CARDIOVASCULAR SYSTEM, BLOOD SUPPLY,
REVASCULARIZATION NON-SURGICAL
SEE ALSO HEART REVASCULARIZATION
SEE ALSO INJURIES, WOUND HEALING
SEE ALSO NERVOUS SYSTEM REGENERATION
** ROlHL-01803-23 0014 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Regenerated endothelium on lipid
accumulation in arterial wall (rabbit)
(contd)
ic research aspects,
grant number.
. •■ JcjuBcv^uvknACir .
GRO
226
HAL
** POlHL-03174-23 0007 Mechanisms of acute vascular
reaction to injury - Healing of injured myocardium-Basal
lamina scaffold (human, rats, dogs)
ROlHL-06975-18 Pathogenesis and prevention of
hypertension (rats)
POlHL-11414-11 0037 Thrombosis and atherosclerosis
program - Vascular intimal injury and healing (rabbits,
rats)
R01HL1286909 Arterial metabolism, diabetes and
atherogenesis (rats, rabbits)
** P50HL-14214-07 0022 Neviborn lung center for hyaline
membrane disease - Functional integrity of surfactant
system-Hyaline membrane disease (lamb, rat)
*♦ ROlHL-16330-06 Aging-tissue injury and repair (rats)
** ROlHL-17747-04 Endothelial injury and regeneration (rats)
P50HL1882803 0006 Specialized center of research in
thrombosis - Etiology and pathogenesis of atherosclerosis
(rabbit, monkey, rat. human)
ROlHL-2036603 Protein turnover and amino acid
transport by lung (rats)
R23HL-2 1225-02 Connective tissue precursor molecules in
the lung (rabbits, hamsters)
R23HL-2 1950-01 Endothelial cell mechanisms in vascular
disease (human)
POlHL-2260201 0004 Pathophysiology of the
endothelium - Endothelium, platelets smooth muscle and
atherosclerosis (rabbits)
ROlHL-23981-01 Acute alveolar injury (dogs)
GROWTH DISORDERS POSTNATAL (SEE ALSO
APPROPRIATE SPECIFICS)
SEE ALSO PREGNANCY DISORDERS, EMBRYO-FETAL GROWTH-
DEVELOPMENT DISORDERS (SEE ALSO
APPROPRIATE SPECIFICS)
ROlHL-09921-13 Mechanisms related to congestive heart
failure (dogs, human, rat)
P60HL-1600806 0015 Wayne State University
comprehensive sickle cell center - Trace elements in sickle
cell disease (human)
ROlHL-1774903 Adrenocortical factors in human
hypertension (human)
M POlKL-19717-02 Response of the lung to injury
** POlHL-19717-02 0026 Response of the lung to injury
Protein depletion and postnatal lung development (rats)
GROWTH DISORDERS PRENATAL
SEE PREGNANCY DISORDERS, EMBRYO-FETAL GROWTH-
DEVELOPMENT DISORDERS (SEE ALSO APPROPRIATE
SPECIFICS)
GROWTH FACTORS (INCL. ANABOLICS)
POlHL-03174-23 0005 Mechanisms of acute vascular
reaction to injury - Renal small vessel didease-Cell and
matrix response (human, mice)
ROlHL-0692416 Humoral and metabolic aspects of
cardiac function (mammals, non-human, human)
R01HL1155111 RNA and protem synthesis in repair of
heart injury (mice, rats)
POlHL-16387-04 0009 The blood vessel and
thrombogenesis - Role of pituitary gland in the
pathogenesis of arteriosclerotic lesions (rats)
R01HL187 14-04 Cardiovascular matrix -Morphogenesis
and maturation (human, chick embryo, mammal)
ROlHL-1882604 Interaction of peptides and target cells
in lung (human)
ROlHL-19746-03 Proliferation and differentiation of
alveolar macrophages (mice, hamsters)
** ROlHL-20 197-02 Maintenance and repair of vascular
endothelium (human, animals)
P50HL-2 1006-02 0004 Specialized center of research in
arteriosclerosis ■ Regulation of growth of human arterial
smooth muscle cells by platelets
GROWTH FACTORS (INCL. ANABOLICS),
EPIDERMAL GROWTH FACTOR
P50HL-1421407 0015 Newborn lung center for hyaline
membrane disease - Hormone effect on cyclic nucleotide
lipid synthesis in developing lung (animal)
** P50HL-14214-07 0020 Newborn lung center for hyaline
membrane disease - Epidermal growth factor effect -Lung
differentiation, maturation (human, rabbit)
P50HL-19190-02 0003 Pulmonary SCOR-Pathophysiology,
management of IRDS - Type II cells-Regulation and
differentiation (rat)
GROWTH HORMONES VERTEBRATE,
SOMATOMEDIN (SULFATION
FACTOR)(THYMIDINE FACTOR)
ROlHL-0692416 Humoral and metabolic aspects of
cardiac function (mammals, non-human, human)
ROlHL-1 1551-11 RNA and protein synthesis in repair of
heart injury (mice, rats)
GROWTH INHIBITORS
SEE ALSO CELL GROWfTH REGULATION, CHALONES
POlHL-06370-17 0004 Cardiopulmonary and renal
pathology research center - Lymphocytes in graft rejection
and immune surveillance (human)
R01HL1862503 Organization of arterial ground substance
(cattle)
ROlHL-19136-03 Mucopolysaccharide metabolism in
cardiac anomalies (rats)
GROWTH MEDIA
POlHL-031 74-23 0005 Mechanisms of acute vascular
reaction to injury - Renal small vessel didease-Cell and
matrix response (human, mice)
POlHL-082 14-15 0023 Chemical and biological properties
of lipids - Lipids in microorganisms and cell cultures
(hamsters, mosquitoes)
P01HL17430-05 0008 Control of coagulation - Cultures
of von Willebrand endothelial cells (pigs)
R23HL-2ie63-01 Regulation of collagen biosynthesis
(chick, embryo)
ROlHL-22883-01 Lung epithelial cell interactions in vitro
GROWTH MICROORGANISMS, MICROBIAL
CULTURE
** POlHL-08214-15 0023 Chemical and biological properties
of lipids - Lipids in microorganisms and ceil cultures
(hamsters, mosquitoes)
GROWTH REGULATION, CELLULAR
SEE CELL GROVKTH REGULATION
GROWTH RETARDATION INTRAUTERINE
SEE PREGNANCY DISORDERS, EMBRYO-FETAL GROWTH-
DEVELOPMENT DISORDERS (SEE ALSO APPROPRIATE
SPECIFICS)
GROWTH RETARDATION POSTNATAL
SEE GROWTH DISORDERS POSTNATAL (SEE ALSO
APPROPRIATE SPECIFICS)
GTP
SEE PURINE NUCLEOTIDES. GUANINE NUCLEOTIDES, GTP
GUANETHIDINE
SEE GUANIDINES, GUANETHIDINE
GUANIDINES
POlHL-16833-04 0001 Hemoglobin and red cell system In
hemoglobinopathies Motility, association and ligand
binding in hemoglobin-Hydrogen exchange
POIHL- 185 74-03 0004 Lipoprotein methodology and
biomedical applications - Fine structure and metabolism of
lipoproteins-EM studies (guinea pigs)
POlHL-18574-03 0005 Lipoprotein methodology and
biomedical applications - Structure and function of
lipoproteins
R23HL-22669-01 Cardiovascular effects from visceral
afferents (dogs)
GUANIDINES, BETHANIDINE
POlHL-1 13 10-12 0078 Mechanisms of cardiovascular
disease - Ventricular arrhythmias in acute myocardial
infarction (dogs)
GUANIDINES, BIGUANIDES,
PHENETHYLBIGUANIDE
POlHL-20993-02 0005 Population dynamics of arterial
cells in atherogenesis - Drugs other than hypolipidemic
drugs affecting atherosclerosis (swine, rabbits)
GUANIDINES, GUANETHIDINE
POlHL-14388-07 0229 Regulation of the circulation in
pathological states - Mechanism of postural hypotension
(human)
R01HL147 13-06 Hypothermia and the heart (bats, guinea
pigs)
P50HL-15061-07 0005 Response of lung to injury - Airway
smooth muscle in health and disease (dogs, guinea pigs)
POlHL-1787104 0009 Kidney, sodium, cardiac output,
arterioles and hypertension - Kidney, sodium, cardiac
output, arterioles and hypertension
POlHL-20552-02 0002 The development and regression of
cardiac hypertrophy - Effect of treatment on the
hypertrophied left ventricle (rats)
** ROlHL-20604-03 Sympathectomy -Cardiovascular and
molecular pharmacology (animals)
R01HL-21673-01 Pathophysiology of venous changes in
hypertension (rats, rabbits, human, dogs)
ROlHL-221 70-01 Factors influencing transmission at
adrenergic synpases
GUANINE
SEE PURINES, GUANINE
GUANOSINE MONOPHOSPHATE
SEE PURINE NUCLEOTIDES, GUANINE NUCLEOTIDES, GMP
GUANOSINE MONOPHOSPHATE CYCLIC
SEE PURINE NUCLEOTIDES, GUANINE NUCLEOTIDES. GMP
CYCLIC
GUANOSINE PHOSPHATES
SEE PURINE NUCLEOTIDES, GUANINE NUCLEOTIDES,
GUANOSINE PHOSPHATES
GUANOSINE TRIPHOSPHATE
SEE PURINE NUCLEOTIDES. GUANINE NUCLEOTIDES, GTP
GUANYLATE CYCLASE
SEE NUCLEOTIDYL-CYCLASES, GUANYLATE CYCLASE
GUENONS
SEE MAMMALS, PRIMATES, MONKEYS AND APES
(ANTHROPOIDS, NON-HUMAN), OLD WORLD MONKEYS
(CATARRHINES)*
GUEREZA
SEE MAMMALS. PRIMATES. MONKEYS AND APES
(ANTHROPOIDS. NON-HUMAN), OLD WORLD MONKEYS
(CATARRHINES)*
GUINEA PIGS
SEE MAMMALS. RODENTS, HYSTRICOMORPHA. GUINEA PiGS*
GUINEA PIGS, R9
SEE MAMMALS, RODENTS. HYSTRICOMORPHA. GUINEA PIGS*
GUT LYMPHOID TISSUE DEPENDENT IMMUNITY
SEE IMMUNITY, HUMORAL IMMUNITY
H ANTIGENS (HISTOCOMPATIBILITY)
SEE TISSUE COMPATIBILITY-TRANSPLANT, ISOALLOANTIGENS
HA ANTIGEN
SEE IMMUNOLOGY, ANTIGENS VIRAL, HEPATITIS B ANTIGEN
(HBAG)
HAA ANTIGEN
SEE IMMUNOLOGY, ANTIGENS VIRAL, HEPATITIS B ANTIGEN
(HBAG)
HABITUATION
SEE PSYCHOLOGY. LEARNING, HABITUATION
HAGEMAN FACTOR
SEE BLOOD COAGUUTION. HAGEMAN FACTOR
HALIDES
SEE HALOGENS (AND HALO COMPOUNDS), GENERAL
HALO COMPOUNDS
SEE HALOGENS (AND HALO COMPOUNDS), GENERAL
HALOALKANES, HALOTHANE
POlHL-06370-17 0006 Cardiopulmonary and renal
pathology research center - Chemical basis of
ultrastructural changes in disease (rats)
ROlHL-10018-11 Effect of aging on beating heart cells in
culture (rats)
ROlHL-13257-09 Inhalation anesthesia on myocardial
metabolism (dogs, swine, human)
ROIHL 1388815 Regulation of respiration
ROlHL-15799-04 Effect of anesthetics on myocardial
function (cats)
P50HL- 17665-04 0026 Study of ischemic heart disease -
Anesthesia -Myocardial ischemia and hemodynamics In
coronary disease (human)
ROlHL-1920303 Surgical approach to congenital heart
diseases (dogs, primates)
ROlHL-19256-03 Arterial baroreceptors in cardiovascular
control (dogs)
HALOALKYLAMINES, CYCLOPHOSPHAMIDE
POlHL-06370-17 0013 Cardiopulmonary and renal
pathology research center - Morphologic analysis of
vascular prosthesis (human, dogs)
R01HL-08e9e-15 0013 Orthotopic heart transplantation -
Transplantation immunology-Cardiac heterotransplantation
(rabbits, dogs)
POlHL-12738-10 0130 Physiologic pharmacology and its
clinical applications - Compatibility enhancement during
cardiac allografting (dogs)
POlHL-1310809 0001 Clinical heart transplantation -
Therapy and prognosis (human)
POlHL-13108-09 0016 Clinical heart transplantation -
Total lymphoid irradiation for immune response (dogs)
R01HL14799-07 Cardiac heterotransplantation-
Immunologic modification (mice, rat)
POlHL-14985-07 0011 Adaptation to hypoxia -
Prostaglandins in the control of the pulmonary circulation
(animals)
P01HL17417-05 0004 Experimental lung transplantation
- Methods for suppressing lung allograft rejection (dogs,
mice)
ROlHL-2006303 Pathogenesis of pulmonary mycoplasma
infections (guinea pigs, mice)
R23HL-21212-02 Alveolar macrophage function in
Pseudomonas infection (dgs)
R23HL-2199701 Pulmonary immunopathology in the
compromised host (guinea pigs)
ROlHL-22301-01 Immunogenetics of chronic pulmonary
inflammation (mice)
R23HL-22448-01 Modulation of heart graft antigenicity by
perfusion (rats)
HALOALKYLAMINES, MECHLORETHAMINE
POlHL-03 174-23 0011 Mechanisms of acute vascular
reaction to injury - Mutagen metabolism by artery wall in
etiology of atherosclerosis (human, animals)
HALOALKYLAMINES, NITROGEN MUSTARDS
SEE ALSO HALOALKYLAMINES, CYCLOPHOSPHAMIDE
SEE ALSO HALOALKYLAMINES, MECHLORaHAMINE
POlHL-21016-02 0004 Sickle cell anemia and other
hemoglobinopathies - Kinetics of sickling
•* POlHL-21016-02 0009 Sickle cell anemia and other
hemoglobinopathies - Nitrogen mustards and their potential
use as antisickling agent
** POlHL-21016-02 0011 Sickle cell anemia and other
hemoglobinopathies - Metabolic effects of antisickling
agents (hamsters)
(contd)
'Excludes routine methodotogy OR covers only general projects which preclude indexing at the specific level.
**0neflte<] significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigatoi's name and grant number.
HAL
aar
HEA
POIHI ?I0I60? 0013 SIcM* call anemia and other
hemoglobinopathies Miciocirculaloiy lesponse to sichlc
cell tfeated with anti sicKlini agents dais)
HALOBACTERIACEAE
Sfr BACURIA, HALOBACIfRIACEAF*
HALOBENZENES, HALOGENATED BIPHENYLS-
TRIPHENYLS AND ANALOGS
POIHI 08214 lb OOOt) Chemical and biological properties
ol lipids Metabolism ol lipids in animals
HAIOETHERS
** ROIHL 13257 09 Inhalation anesthesia on myocardial
metabolism (dogs, swine, human)
HALOETHERS, ETHRANE
ROIHL 13888 IS Regulation ol respiration
HALOETHERS, FORANE
ROIHL 1S392'06 Autonomic and circulatory actions ol
anesthetics (dog. cat. rabbit, monkey)
HAIOETHERS, METHOXYFIURANE
P50HL 17665 04 0026 Study o( ischemic heart disease
Anesthesia Myocardial ischemia and hemodynamics in
coronary disease (human)
HALO FATTY ACIDS, CHLORO FATTY ACIDS,
DICHLOROACETATE
ROIHL 21209 02 Alterations of metabolism in ischemic
myocardium (swine)
HALO FATTY ACIDS, lODO FATTY ACIDS
P01HL11351-12 0015 Cellular and molecular
mechanisms of myocardial function Effects of hypoxia
and ischemia on ion exchange and heart function (rabbits)
POIHL- 1498507 0012 Adaptation to hypoxia Direct
effect of hypoxia on pulmonary vascular smooth muscle
(rats, dogs)
HALOFENATE
SEE PHENOXYACETIC ACIDS. HALOFENATE
HALOGENATED BIPHENYLS-TRIPHENYLS AND
ANALOGS
SEE HALOBENZENES. HALOGENATED BIPHENYLS-TRIPHENYLS
AND ANALOGS
HALOGENATION, lODINATION-DEIODINATION
N01HI'3292eiO Analysis of lipoproteins (animals)
HALOGENS (AND HALO COMPOUNDS),
GENERAL
** P01HL-0637017 0006 Cardiopulmonary and renal
pathology research center ■ Chemical basis of
ultrastructural changes in disease (rats)
ROlHL-20725'02 Mechanisms and cellular functions of ion
transport
HALOGENS, CHLORINE (COMPOUNDS) SEE
ALSO SPECIFICS
SEE ALSO POTASSIUM CHLORIDE
SEE ALSO SODIUM CHLORIDE
P01HL1215711 0049 Functions and mechanisms of cell
membrane ion transport - Ouabaininsensitive cation
transport in duck red cells
PClHL-12157-11 0058 Functions and mechanisms of cell
membrane ion transport - Ionic and osmotic regulation in
toadfish-A euryhaline aglomerular teleost
ROlHL-1287909 0008 Pulmonary transport and
metabolism in vivo - Stop-flow technique for permeability
measurements
ROlHL-18819-07 Chemical studies on sickle cell
hemoglobin (human)
POlHL-19737-02 0004 Cellular and molecular aspects of
respiratory physiology - Rapid reactions and erythrocyte
exchanges of blood during respiratory transport
ROlHL-20365-03 Molecular mechanisms of anion transport
POlHL-20592-02 0013 Cell biology of cardiac and
skeletal muscle - Sarcoplasmic reticulum in skinned
muscle cells (frogs)
ROlHL-2062202 Pulmonary uptake and accumulation of
drugs (rabbits, rats)
ROlHL-20725-02 Mechanisms and cellular functions of ion
transport
** ROlHL-22390-01 Effect of chloride on renin (rats, dogs)
ROlHL-22569-02 Intestinal secretion-Capillary and tissue
forces (dogs, cats)
HALOGENS, FLUORINE (COMPOUNDS) SEE
ALSO SPECIFICS
SEE ALSO RADIOISOTOPES. FLUORINE
P01HL06308-18 0025 Mechanisms and therapy of
circulatory disease - Subcellular calcium pools in the
genesis of arrhythmias (dogs)
POlHL'06314-17 0055 Immunologic mechanisms in
cardiovascular disease - Genetics and cell biology
HALOOLEFINS, VINYLEOENE CHLORIDE
** P50HL-191 70-02 0005 Harvard pulmonary SCOR-Chronic
diseases of the airways - Pulmonary toxicology of plastics
intermediates and pyrolysis products (animal)
HALOPERIDOL
SEE PIPERIDINES, HALOPERIDOL
HALOPROTEINS, PROTEIN BOUND IODINE
SI I Also HAIOPROIIINS. IIIYROXINf BINDING PROUINS
ROIHI 18519 03 Albumin, endothelium Hnd
hemocompatibility (human, dog. cattle, idbbit)
HALOPROTEINS, THYROXINE BINDING
PROTEINS
SFF ALSO HALOPROTEINS. PROfEIN BOUND IODINE
ROIHL 02063 23 Biochemistry and function of lipids and
cell membranes (human, yeast, animals)
HALOPYRIMIDINE NUCLEOSIDES, HALOURACIL
NUCLEOSIDES, S-BROMODEOXYURIDINE
** POIHL 18708 03 0007 Oxygen, energy and contractility in
cardiac tissue Surfaces, energy requirements, and
contractile proteins of cardiac cell in vitro
HALOTHANE
SEE HALOALKANES. HALOTHANE
HAMSTERS
SEE MAMMALS. RODENTS, MYOMORPHA, HAMSTERS*
HAMSTERS, ALBINO
SEE MAMMALS, RODENTS, MYOMORPHA, HAMSTERS*
HAMSTERS, CHINESE
SEE MAMMALS. RODENTS, MYOMORPHA. HAMSTERS*
HAMSTERS, GOLDEN
SEE MAMMALS, RODENTS, MYOMORPHA, HAMSTERS*
HAMSTERS, SYRIAN
SEE MAMMALS, RODENTS, MYOMORPHA. HAMSTERS*
HAMSTERS, SYRIAN GOLDEN
SEE MAMMALS, RODENTS, MYOMORPHA, HAMSTERS*
HAMSTERS, WHITE
SEE MAMMALS. RODENTS. MYOMORPHA, HAMSTERS*
HAND
SEE SKELETAL SYSTEM, LIMB, HAND
HANDBOOK
SEE PUBLICATIONS, HANDBOOK
HAPALE
SEE MAMMALS, PRIMATES, MONKEYS AND APES
(ANTHROPOIDS, NON-HUMAN), NEW WORLD MONKEYS
(PLATYRHINES)*
HAPTENS
SEE IMMUNOLOGY, HAPTENS
HAPTOGLOBINS
SEE HEMOPROTEINS, HAPTOGLOBINS
HARDWARE, COMPUTERS
SEE COMPUTER, DESIGN AND EVALUATION OF COMPUTERS
(INCL. HARDWARE)
HARES
SEE MAMMALS, LAGOMORPHS*
HASHISH
SEE ALKALOIDS, CANNABIS
HAWAIIAN S
SEE SOCIAL GROUPS, ETHNIC. AMERICANS, HAWAIIANS
HAY FEVER
SEE HYPERSENSITIVITY. RESPIRATORY HYPERSENSITIVITY,
HAY FEVER
HAZARDS, OCCUPATIONAL
SEE OCCUPATIONAL HEALTH. OCCUPATIONAL HAZARDS
HAZARDS OF MEDICAL EQUIPMENT
SEE BIOMEDICAL ENGINEERING. MEDICAL EQUIPMENT
SAFETY
HDL (LIPOPROTEINS)
SEE LIPOPROTEINS BLOOD. HDL
HEAD AND NECK INJURIES
SEE INJURIES. HEAD AND NECK
HEAD INJURIES
SEE INJURIES. HEAD AND NECK
HEADACHE
SEE NEUROLOGIC MANIFESTATIONS, HEADACHE
HEALING
SEE INJURIES, WOUND HEALING
HEALTH (ALSO PHYSICAL ACTIVITY)
SEE ALSO MENTAL HEALTH
SEE ALSO POPULATION STUDIES HUMAN, MORBIDITY
SEE ALSO PSYCHOLOGY, ATTITUDE TO HEALTH AND HEALTH
PROBLEMS
ROlHL-19877-02 Prevention of high blood pressure in
children
HEALTH, DISEASE PREVENTION AND CONTROL
SEE ALSO CARDIOVASCULAR DISORDERS PREVENTION AND
CONTROL (NOT INCLUDED ELSEWHERE)
SEE ALSO COMMUNICABLE DISEASE CONTROL
SEE ALSO DIAGNOSTIC SERVICES, MASS SCREENING
Sff Also DIAGNOSTIC TFSfS, fARlY DIAGNOSf,*
SfF Also fPIOIMIOtOGY AND OlSfAM CONIHOI SIIJDY
SFCIION
S[[ ALSO POPUlAflON SIUDKS HUMAN. (I'iniMIOlOG*
SEE ALSO lOXICOlOGY. POISON CONIROI ANf) PHIVINIION
ROIHI 05806 18 Analysis ol antiarrhythmic agent-, (dogt,
rabbits)
POIHI 06285 18 0143 Cardiovascular respiratory
physiology and biochemistry Myocardial ischemia (human.
dogs, lambs)
POIHL 09011 15 0020 A research and resource program
in blood Passive immuniiation in the prevention of
transmission of hepatitis B (human)
POIHL 09011 15 0023 A research and resource program
in blood Evaluation ol hepatitis B vaccine in endemic
settings (human)
ROIHL 13754 08 Postoperative thromboembolism in
surgical patients (human)
P60HL 15160-07 0003 Center for sickle cell disease -
Genetic counseling in hemoglobinopathies Dimensions,
effectiveness
P60HL 15170 05 0006 Support for center for sickle celt
anemia Pediatric services Comprehensive clinic
ROIHL 15504 05 Animal model for studies on averting
atherosclerosis (swine)
ROIHL 16908-04 Myocardial function, risk factors and
future CHD (men)
ROIHL'16909'04 Myocardial function, risk factors and
future CHD (men)
ROIHL 1775403 Pathogenesis and prevention of
hypertension sequelae (rats)
ROIHL 18097 04 Pathogenesis of acute renal failure (rats)
R25HL 18406 03 Adherence to hypertensive medical
regimens (human)
ROlHL-18527-03 Subcellular response of heart to
functional overload (hamsters, rats)
ROIHL 18610-03 Early intervention of age related arterial
changes (pigeon)
ROlHL-18891 02 Electrolyte intake and blood pressure in
hypertension (human)
R01HL1911203 Atherosclerosis studies (monkeys)
ROlHL-1930703 Problems in prevention of rheumatic
heart disease (human)
ROlHL-19782-02 Pharmacologic studies on the ischemic
heart (dogs)
ROlHL-19858-03 UMMC-Blood pressure precursors and
consequences (human)
ROlHL-19870-03 Hypertensive progeny-Physical and
humoral precursor search
ROlHL-19922-03 Childhood determinants of blood pressure
ROlHL-19929-03 High blood pressure in the young.
prevalence and precursors (human)
R01HL19930-03
newborn twins
ROlHL-19962-03
A prospective study-Blood pressure in
High blood pressure in young people in
Tecumseh
ROlHL-19984-02 Blood pressure and immunogenetic
factors in the young (human)
ROlHL-20005-03 Factors in blood pressure levels of
children
ROlHL-20034-03 Hypertension-Psychophysiologic and
genetic precursors (human)
ROlHL-20244-02 he impact of hypertension information
ROlHL-20245-01 The impact of hypertension information
ROlHL-2024701 The impact of hypertension information
ROlHL-20248-01 The impact of hypertension information
ROlHL-20374-03 Myocardial function-Risk factors and
future CHD (human)
ROlHL-20720-02 Myocardial protection during
cardiopulmonary bypass (dogs)
ROlHL-20750-01 Studies in sickle cell disease (human)
ROlHL-20856-02 Platelet transfusions-Usage and
complications (human)
POlHL-22163-01 0003 Surface thrombogenesis-
Mechanisms and prevention - In vivo mechanisms of
biomaterial thrombogenesis and its prevention (baboons)
ROlHL-22219-01 Prostacyclin and peroxides in blood and
membrane disease
ROlHL-22298-02 Origins of hypertension (human)
ROlHL-22472-01 Smoking risk-factor reduction-
Maintenance strategies (human)
R23HL-22947 01 Experimental systems to improve youth
behavior (smoking prevention)
ROlHL-23194-02 Genetics of hypertension and associated
variables (human)
NOlHR-62931-02 Development and evaluation of
continuing education in pulmonary medicine
NOlHR-62948-04 Evaluate antenatal steroid therapy in
neonatal respiratory distress syndrome
NOlHR-62949-05 Evaluate antenatal steroid therapy in
neonatal respiratoiy distress syndrome
NOlHR-62950-04 Evaluate antenatal steroid therapy in
neonatal respiratory distress syndrome
NOlHR-62951-04 Evaluate antenatal steroid therapy in
neonatal respiratory distress syndrome
NOlHR-62952-05 Evaluate antenatal steroid therapy in
neonatal respiratory distress syndrome
NOlHV-2291711 Lipid research clinic (human)
NOlHV.22971-07 Prevention of coronary heart disease
(human)
' NOlHV-22976-07 Multiple risk factor intervention trial.
prevention of coronary heart disease
(contd)
*Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
••Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
HEA
** NOlHV-22977-08 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22979-07 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22980-06 Intervention trial for the prevention of
coronary heart disease (human)
** NOlHV-22981-10 Intervention trial for the prevention of
coronary heart disease (human)
** NOlHV-22982-07 Intervention trial for prevention of
coronary heart disease (human)
** NOlHV-22983-07 Intervention trial for the prevention of
coronary heart disease (human)
** NOlHV-33 101-06 Development and conduct of a multiple
risk factor intervention trial (human)
** NOlHV-3310509 Intervention trial for prevention of
coronary heart disease (human)
'* NOlHV-33106-06 Intervention trial for the prevention of
coronary heart disease (human)
** NOlHV-33 108-04 Prevention of coronary heart disease
(human)
** N01HV-33I0904 Intervention trial for the prevention of
coronary heart disease (human)
** NOIHV 33110-04 Prevention of coronary heart disease
(human)
♦* NOlHV-4291107 ECG center for prevention of coronary
heart disease (human)
** N01HV-42929-08 Risk factor intervention trial for the
prevention of CHD (human)
** NOlHV-4293009 Risk factor intervention trial for the
prevention of CHD (human)
** NOlHV-42931-07 Risk factor intervention trail for the
prevention of CHD (men)
** NOlHV-42932-05 Risk factor intervention trial for the
prevention of CHD (human)
** NOlHV-52901-06 Aspirinmyocardial infarction study
** NOlHV-72984-03 High blood pressure control program
(human)
** NOlHV-72986-02 High blood pressure control program
(human)
** NOlHV-72987-02 High blood pressure control program
(human)
** NOlHV-72989-02 High blood pressure control program
(human)
** NOlHV-72990-00 High blood pressure control program
(human)
HEALTH, PHYSICAL ACTIVITY, EXERCISE
** ROlHL-02228-24 Respiration, circulation, and heat
regulation in exercise (bird, mammals)
ROlHL-0342918 Central nervous system and coronary
heart disease (human)
ROlHL-05883-18 0002 Reflex control of resistance and
capacitance vessels ■ Adenosine, adenine nucleotides and
vascular smooth muscle (dog)
ROlHL-0588318 0006 Reflex control of resistance and
capacitance vessels - Cardiopulmonary vagal afferents in
the conscious dog
ROlHL-0588318 0007 Reflex control of resistance and
capacitance vessels • Prostaglandins and skeletal muscle
blood flow (dogs)
ROlHL-0594918 Biochemistry of muscle contraction (rats,
rabbits)
** ROlHL-0614318 Response of the totally denervated heart
to exercise (dogs)
POlHL-06285-18 0153 Cardiovascular-respiratory
physiology and biochemistry ■ Myocardial mechanics and
pharmacology in isolated papillary muscle (animals)
POlHL-06285-18 0181 Cardiovascular-respiratory
physiology and biochemistry - Regulation of respiration-
Role of vagus nerve (dogs)
1^ POlHL-06296-18 Cardiovascular and pulmonary
adaptation to stress
POlHL-06296-18 0002 Cardiovascular and pulmonary
adaptation to stress • Respiratory muscle blood flow,
mechanics and metabolism (human, dog)
POlHL-06308-18 0044 Mechanisms and therapy of
circulatory disease - Echocardiography to determine site of
ectopic impulse formation (human, dogs)
POlHL-06312-17 0028 Surgical cardiology - Coronary flow
in the transplanted denervated heart (dogs)
P01HL06835-17 0016 Cardiovascular disease Metabolic
interactions to polyunsaturated fatty acids in atherogenic
diet (dogs)
POlHL-06835-17 0064 Cardiovascular disease ■ Studies
in atherosclerosis (human, animals)
POlHL-07896-15 0014 Environmental biomedical research
program - Mechanisms of respiration and circulation
(human, dogs)
•* POlHL-07896-15 0048 Environmental biomedical research
program - Respiratory performance in divers at 1400 FSW
POlHL-07896-15 0050 Environmental biomedical research
program Fundamental decompression concepts using the
rat animal model
POlHL-0868215 0022 Regulation of the cardiovascular
system - Blood pressure responses and preganglionic
sympathetic outflow (cat)
POlHL-08805 15 0047 Regulation of ventilation and
pulmonary circulation - Extracranial metabolic control of
ventilation (dogs, goats)
POlHL-08899 14 0018 Tolerance to respiratory gases in
health and disease • Effects of respiratory gases at
extreme pressures (human)
228
** POlHL-08899-14 0031 Tolerance to respiratory gases in
health and disease Studies in exercise (human, dogs)
** POlHL-0889914 0035 Tolerance to respiratory gases in
health and disease - Simulation of the increased
metabolism of exercise (dogs)
** P01HL08899-14 0036 Tolerance to respiratory gases in
health and disease - Chemical and neurogenic components
of respiratory simulation in exercise (human)
** POlHL-08899-14 0041 Tolerance to respiratory gases in
health and disease - Blood gas transport and brain
circulatory control (human)
ROlHL-10384-13 Blood flow and nucleotide metabolism
(animals)
M POlHL-10539-12 Pathophysiology of circulation
** POlHL-10539-12 0031 Pathophysiology of circulation -
Post myocardial infarction care-Psychological aspects
(human)
** POlHL-10539-12 0064 Pathophysiology of circulation -
Exercise physiology and pathophysiology (human)
POlHL-10539-12 0065 Pathophysiology of circulation -
Physiologic correlates of relaxation (human)
ROlHL-10622-12 Volumes and compliance of pulmonary
circulation (human, dogs)
POlHL-1131012 0079 (Mechanisms of cardiovascular
disease • Electrophysiological studies of complete heart
block (human)
POlHL-1167811 0017 Cardiovascular dynamics and their
control - Overall control of circulation-Mathematical
analyses
** ROlHL-11907-08 Mechanisms of physiological responses
to exercise (human, dogs)
ROlHL-12085-10 Lipoprotein-carbohydrate metabolism
(human, rats)
P01HL12373-10 0002 Cardiopulmonary physiology and
pathophysiology Determinants of performance of the
whole heart (dogs)
ROlHL-124 15-10 Evaluation of left ventricular function
(dogs, rabbits)
ROlHL-12607-10 Dynamics of pulsatile blood flow (human,
dogs, rats)
POlHL-13108-09 0019 Clinical heart transplantation ■
Effect of autonomic nervous system on arrhythmias
(human)
POlHL-13108-09 0020 Clinical heart transplantation -
Autonomic neural studies in the denervated heart (human)
POlHL-13108-09 0022 Clinical heart transplantation -
Studies on cardiac receptors (human)
** POIHL- 13 108-09 0023 Clinical heart transplantation -
Adaptive mechanisms of the denervated heart (human)
** R01HL13233-08 Cardiorespiratory control in exercise
(human)
R01HL13841 16 Respiration during altitude
acclimatization (goats, dogs, rats, rabbits)
ROlHL-13888-15 Regulation of respiration
" P50HL1413805 0010 Center for research on
atherosclerosis - Diet and exercise as therapy in men with
premature atherosclerosis
R01HL14378-07 Lipemias and reconstructive cardiac
surgery (human)
POlHL-144 14-07 0003 Environmental influences on
cardiorespiratory and cellular functions - Exposure to
abnormal gaseous environments (human, dogs, rabbits)
P01HL144 14-07 0008 Environmental influences on
cardiorespiratory and cellular functions - Energetics of
swimming (human)
** POlHL-144 14-07 0015 Environmental influences on
cardiorespiratory and cellular functions - Control of the
cardiovascular system (dogs)
P01HL-I4414-07 9002 Environmental influences on
cardiorespiratory and cellular functions - Core-Computer
facility
ROlHL-14692-06 Alpha 1 antitrypsin deficiency and
pulmonary disease (human)
ROlHL-14967-06 Chemoreceptor function in dynamic
ventilatory control (human, dogs)
POlHL-14985-07 0002 Adaptation to hypoxia - Oxygen
transport in man at high altitude
POlHL-14985-07 0005 Adaptation to hypoxia • Control
mechanisms in the pulmonary microcirculation (animals)
** POlHL-14985-07 0008 Adaptation to hypoxia - Ventilatory
drive and exercise capacity (human, dogs)
POlHL-14985-07 0014 Adaptation to hypoxia - High
altitude pulmonary edema (human, rats, dogs)
ROlHL-151 74-06 CV disease epidemiology-Second
generation studies (human)
POlHL-15194-07 0019 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation, bypass
grafts and diastolic driving pressure (human, dogs)
ROlHL-15416-06 Cardiovascular control in normal and
disease states (dogs, baboons)
** ROlHL-15498-06 Effects of physical training on heart
(rats)
ROlHL-1560706 Physiological control of splanchnic
circulation (dogs)
ROlHL-15659-05 Dynamic isolation studies of control of
respiration (human)
P60HL-15996-06 0005 Cincinnati comprehensive sickle
cell center Factors precipitating crises (human)
** R01HL16292-05 0009 Surgery and non-obstructive
coronary insufficiency - Exercise and supply-demand
balance (human)
•Excludes routine methodology OR covers only general projects which preclude Indexing at the specific level.
**Onented significantly to above subject
M Grant has subprojects describing specif
See Appendix for investigator's name and
HEA
** ROlHL-16292-05 0010 Surgery and non-obstructive
coronary insufficiency - Effects of exercise on flow
distribution (dogs)
R01HL16325-03 Breathing patterns in man
** ROlHL-16390-05 Cardiopulmonary control coupling in
exercise (dogs)
** ROlHL-16420-02 Effect of training-detraining on the rat
heart
** ROlHL-16463-05 Localization of airways obstruction and
responses
ROIHL 16656-06 Left ventricular function in exercise
(dogs)
R01HL16760-05 Dynamic control of coronary blood flow
(dogs)
ROlHL-16828-04 Gradient and transport of oxygen in
tissue and organs (mammals)
POlHL-16910-05 0001 Regulation of the peripheral
circulation ■ Quantitative studies of microcirculatory control
(bats)
POlHL-16910-05 0006 Regulation of the peripheral
circulation - Regulation of blood flow distribution (baboons,
dogs)
POlHL-16910-05 0007 Regulation of the peripheral
circulation CNS-Behavioral influences on circulation
(baboons)
P60HL 17265-04 0002 Community blood resource center
support - Research -Human factor VIII
P01HL1738205 0001 Chemical mediators of acute
pulmonary disorders - Chemical mediators and respiratory
mechanics in humans
ROlHL-17403-03 Metabolic control of cardiac output
(dogs)
** P50HL-17669-04 0008 Ischemic heart disease center
(SCOR) • Segmental ventricular dysfunction during stress-
induced ischemia (dog, human)
P50HL- 17682-04 0013 Study of ischemic heart disease •
Chronic ischemic heart disease-Myocardial function and
metabolism (dogs, swine)
** P50HL-1768204 0016 Study of ischemic heart disease ■
Endurance exercise -Prevention and rehabilitation in
ischemic heart disease (pig)
** ROlHL-17689-06 Neurophysiologic studies of respiratory
control (cats)
POlHL-17731-04 0010 Physiological basis of pulmonary
disease - Gas exchange kinetics (dogs)
ROlHL-1773203 Peripheral venomotor control in thermal
stress (human)
ROlHL-17808-03 Effect of altered oxygen affinity on
oxygen transport (human, rats)
** ROlHL-1780904 Effects of exercise on the coronary
vasculature (rat, dog)
** R01HL17873-04 Pathophysiology of exercise-induced
asthma (human)
** ROIHL 1793204 Blood flow regulation in muscle (cats)
** ROlHL-17993-04 0004 Ventricular dynamics from
surgically inserted markers - Exercise training following
coronary artery bypass graft surgery (human)
** ROlHL-17993-04 0008 Ventricular dynamics from
surgically inserted markers - Exercise after coronary bypass
(human)
ROlHL-18007-05 Neural mechanisms controling motor act
of breathing (cats, human)
R01HL18020-04 Splanchnic hemodynamics in man
ROlHL-18145-03 Oxygen transport mechanisms in hypoxia
(dogs, rats, rabbits)
" ROlHL-18527-03 Subcellular response of heart to
functional overload (hamsters, rats)
** ROlHL-18560-03 Cardiovascular adaptation to stress
(miniature swine)
POlHL-18574-03 0001 Lipoprotein methodology and
biomedical applications - Ultracentrifugal and
electrophoretic lipoprotein methodology-Applications
ROlHL-1879804 0003 Nervous and ionic factors in
sudden cardiac death ■ Left stellectomy in the prevention
of sudden death (dogs)
ROlHL-19056-03 Blood triglycerides and lipoprotein lipase
in the lung (rats)
** P50HL-19170-02 0004 Harvard pulmonary SCOR-Chronic
diseases of the airways - Exercise, increased ventilation
effect on airway exposure and responses (rodent)
P50HL-19170-02 0006 Harvard pulmonary SCOR-Chronic
diseases of the airways - Mechanism of overdistension
(human, animal)
P50HL-19170-02 0007 Harvard pulmonary SCOR-Chronic
diseases of the airways - Therapy effect on airway
obstruction in acute asthma (human)
P50HL-1917002 0009 Harvard pulmonary SCOR-Chronic
diseases of the airways - Ventilatory muscle training in
chronic obstructive pulmonary disease (human)
ROlHL-19248-03 Breathing pattern variation and
mechanical influences
** R01HL19410-03 Dynamic interrelations underlying
exercise hyperpnea (human)
POlHL-1971702 0008 Response of the lung to injury ■
Experimental models of lung disease
POlHL-19717-02 0046 Response of the lung to injury -
Bioengineering section
POlHL-19737-02 0005 Cellular and molecular aspects of
respiratory physiology - Interaction of respiratory exchanges
and blood gas parameters (human, animals)
(contd)
ic research aspects,
grant number.
HEA
329
POIHL 19737 02 0009 Cellulat ind molacular aspects of
respiratory ptiysiology Regulation ol tissue o>ygen tension
and body carbon monoxide stoies (human, dogs)
ROIHI 19839 09 Factors in youth predisposing to chronic
diseases dormer college sludentsl
ROIHL 20187 01 Evaluation ot exercise cardiac
rehabilitation program (40 !>b year old men)
ROIHL 20253 02 Effects at exercise on the heart and its
blood supply (dogs)
ROIHL 2032801 Noninvasive assessment of autonomic
cardiac control (dogs)
ROIHL 20347 02 Bolus-response measurement of lung
function (human)
ROIHL'20408'03 Hyperlipidemia in diabetics during
muscular training (human)
ROIHL'20597 02 Electrophysiologic correlates ol
myocardial ischemia (human, dogs, rabbits)
ROIHL 20634 01 Blood volume and venous return in
thermal strain (human)
ROIHL 2066202 Physical activity, fitness and
epidemiology ol CHD
ROIHL 2066302 Regulation of skin blood How in man
ROlHL-20827 02 Effects ol hypertrophy on the coronary
circulation (dogs)
ROlHL-2089503 0002 Cineangiographic studies of
cardiovascular system Coronary disease Regional
myocardial blood flow (human, dog)
ROlHL-2095402 Hyperlipoproteinemia (rats, human)
R23HL 2096802 Respiratory failure Control and muscle
dysfunction (human)
R01HL2103401 Compensatory responses to arterial
occlusion (dogs)
ROlHL-2111701
disease (human)
' ROlHL-2112602
children
' ROlHL-21245-02 Influence of chronic exercise on
hypertension (rats, primates)
R01HL-21282-01 Dynamics of interstitial space in whole
animals (rats)
R23HL-2129802
ROlHL-21307-01
population
R23HL 2139301
(rats)
ROlHL-21427-02
patients
* ROlHL-21578-01
adolescent
ROlHL-21872-01
heart (dogs)
* R23HL-21901-01
exercise (rats)
R18HL-21906-01
reduction study
■ R23HL-21954-01
cystic fibrosis
' R23HL-21990-01
exercise (dogs)
R23HL-22004-01 Imaging and ECG studies in acute and
chronic IHD (human)
ROlHL-22022-01 Respiratory muscle dysfunction in
respiratory failure (human)
* ROlHL-22154-01 Cardiac adaptation to physical training
(dog)
* ROlHL-22215-01 Effects of exercise-training in ischemic
heart disease (human)
* ROlHL-22361-01 Regulation of cardiac adaptation to
exercise (rats)
ROlHL-22378-01 Psyco-somatic predictors of CHD in
adolescence (human)
Reflex control ol resistance and
Prostaglendins and skeletal muscle
Altitude adaptation in chronic lung
Exercise-induced bronchospasm in
Coronary vasomotion (dogs, pigs)
Risk reduction and exercise fitness in a
Cardiac adaptation to aging and stress
Behavioral changes in post infarction
Eftect of exercise upon the hypertensive
Myocardial perfusion in the hypertrophied
Hypertension, microvascular control and
Stanford five city multifactor risk
Exercise conditioning in patients with
Accuracy of the ventilatory response to
Hemodynamics of the clinical
Blood cell-mediated pulmonary (human)
Cardiovascular effects from visceral
ROlHL-2250601
hypertensions
R23HL-22621-01
R23HL-22669-01
afterents (dogs)
** ROlHL-22910-01 Control of breathing pattern in health
and disease (human, animals)
R23HL-2297501 Dynamics of autorcgulation of muscle
blood flow (dogs)
ROlHL-22977-01 Role of vasoconstrictor mechanisms in
heart failure (human, dogs)
** ROlHL-23206-01 Repetitive exercise and cardiac
enlargement (dogs)
NOlHR-72974-01 Self-management systems tor asthmatic
children
NOlHV-62955-04 Data collection in clinical pathology and
morbid anatomy (men)
HEALTH, PHYSICAL ACTIVITY, FATIGUE
R01HL-1410207 Human physiology at 5360 meters-
Mountain environment
POlHL-19737-02 0008 Cellular and molecular aspects ol
respiratory physiology • Kinetics of movement of acid
metabolites from cell to capillary blood (dogs)
HEALTH, PHYSICAL ACTIVITY, REST
SEE ALSO PSYCHIC ACTIVITY LEVEL, SLEEP
ROIHL-03290-22 Controls of cardiac and vascular smooth
muscles (cats, rats, dogs)
ROlHL-05883-18 0006 Reflex control of resistance and
capacitance vessels - Cardiopulmonary vagal afferents in
the conscious dog
ROIHI 05883 18 0007
capacitance vessels
blood tlow (dogs)
POIHl 06308 18 0043 Mechanisms and therapy of
circulatory disease Exercise and echocardiographic
examining techniques (human)
POIHL 08899 14 0031 Tolerance to respiratory gases in
health and disease Studies in exercise (human, dogs)
ROIHL 10622 12 Volumes and compliance of pulmonary
circulation (human, dogs)
POIHL 13108 09 0023 Clinical heart transplantation
Adaptive mechanisms of the denervated heart (human)
POIHL 13480 09 0028 Cardiac electrophysiology Stress
electrocardiography (human, dogs)
ROIHL 14102 07 Human physiology at 5360 meters -
Mountain environment
POIHL 1438807 0229 Regulation of the circulation in
pathological states Mechanism of postural hypotension
(human)
POIHL 15194 07 0019 Pathophysiology of
caidiupU'iiiuiiaiy dysfunction Coioiury ciiculalicn. bypass
grafts and diastolic driving pressure (human, dogs)
POIHL 15194 07 0020 Pathophysiology ol
cardiopulmonary dysfunction Coronary circulation in
arteriographically normal arteries (human)
ROIHL 1532503 Breathing patterns in man
ROlHL-18007-05 Neural mechanisms controling motor act
of breathing (cats, human)
ROIHL 18492-03 Measurement of regional coronary How
reserve (human, dogs)
ROIHL 19343-03 Behavioral influences on cardiac
contractility (monkeys)
M ROlHL-19451-03 Functional characteristics ol the left
heart
ROIHL 19451-03 0001 Functional characteristics ol the
left heart - Ventricular performance using epicardial
radiopaque markers (human)
POlHL-197 17-02 0046 Response ol the lung to injury ■
Bioengineering section
ROlHL-19844-02 Behavioral control ol essential
hypertension (human)
ROIHL-20328-01 Noninvasive assessment ol autonomic
cardiac control (dogs)
ROlHL-2059803 The coronary vascular response to
ischemia (dogs, pigs)
ROlHL-20678-02 Cardiovascular adaptation to stress in
disease states (dogs)
ROlHL-2187201 Myocardial perfusion in the hypertrophied
heart (dogs)
R23HL-22004-01 Imaging and ECG studies in acute and
chronic IHD (human)
ROlHL-22022-01 Respiratory muscle dyslunction in
respiratory failure (human)
HEALTH, PHYSICAL FITNESS
** POlHL-1053912 0031 Pathophysiology ol circulation •
Post myocardial infarction care-Psychological aspects
(human)
POlHL-1053912 0064 Pathophysiology ol circulation -
Exercise physiology and pathophysiology (human)
** POlHL-14388-07 0160 Regulation ol the circulation in
pathological states • Mechanism ol the antihypertensive
effect of training (rats)
** POlHL-14985-07 0008 Adaptation to hypoxia - Ventilatory
drive and exercise capacity (human, dogs)
R01HL17246-03 Oxygen uptake at one minute of exercise
(human)
P50HL-17670-04 0015 Study ol ischemic heart disease -
Radionuclide studies ol myocardial ischemia (human)
** ROlHL-18235-03
lactors (human)
Cardiovascular Illness and other risk
Factors in blood pressure levels ol
" ROlHL-20005-03
children
** ROlHL-2066202 Physical activity, litness and
epidemiology ol CHD
ROlHL-21 126-02 Exercise-induced bronchospasm in
children
HEALTH ADMINISTRATION
** POlHL-14388-07 9005 Regulation ol the circulation in
pathological states - Core administration
HEALTH AND SCIENTIFIC ORGANIZATIONS
P60HL-1 7265-04 0010 Community blood resource center
support - Blood resources educational program
HEALTH AND SCIENTIFIC, ORGANIZATIONS,
INTERNATIONAL
SEE ALSO HEALTH AND SCIENTIFIC ORGANIZATIONS,
VOLUNTARY HEALTH ORGANIZATIONS, RED
CROSS
** ROlHL-10582-12 Thrombosis and hemostasis-Analysis.
methods and standards (human, cattle, venom)
HEALTH AND SCIENTIFIC ORGANIZATIONS,
INTERNATIONAL, WHO
ROlHL-21039-02 Vascular lesions ol diabetes in Oklahoma
Indians
HEALTH AND SCIENTIFIC ORGANIZATIONS,
VOLUNTARY HEALTH ORGANIZATIONS
** P60HL-151 58-07 0027 Comprehensive sickle cell center -
Community advisory board-Nancy Cobb house
HEA
HEALTH AND SCIENTIFIC ORGANIZATIONS,
VOLUNTARY HEALTH ORGANIZATIONS, RED
CROSS
** HOIHl 13881 08 The American Red Cross National
Fractionation Center
HEALTH CARE COSTS-FINANCING
SEI HEAIfH ECONOMICS HIAIIH CARE COSTS FINANCING
HEALTH CARE DELIVERY
SEE HEAIIH CARE SFRVICfS, PAIIENI CARE MANAGEMENT
HEALTH CARE FACILITIES (GENERAL)
POIHL 12373 10 0020 Cardiopulmonary physiology and
pathophysiology Hospitalization and patient care
Pulmonary SCOR Airways
Physiology core (human, animal)
Pulmonary SCOR Airways
Pathology core (human, dogs)
Pulmonary SCOR Airways
Radiology core (human)
Vermont Lung Center Health
P50HL 1413607 9002
obstructive diseases
P50HL 14136 07 9003
obstructive diseases
P50HL1413607 9004
obstructive diseases
P60HL 17292 04 0023
iniormation resources
*• NOIHV 22939 12 Hypertension detection and lollow up
program center
NOlHV-22945 11 Cooperative hypertension detection and
lollow up study (human)
HEALTH CARE FACILITIES, OUTPATIENT
FACILITIES
SEE ALSO HOSPITALS. OUTPATIENT FACILITIES
P60HL 1516207 0001 Comprehensive sickle cell center
Core program- Patient care
P60HL 15168-07 0002
center ■ Patient care
Comprehensive sickle cell disease
Comprehensive sickle cell disease
P60HL 1516807 0006
center - Core center
P60HL15170-05 0006 Support for center for sickle cell
anemia • Pediatric services-Comprehensive clinic
P60HL-1 5996-06 0006 Cincinnati comprehensive sickle
cell center Education
P60HL-1599606 0007 Cincinnati comprehensive sickle
cell center ■ Screening and counseling
P60HL- 15996-06 0008 Cincinnati comprehensive sickle
cell center - Patient care (children, adults)
P60HL- 15999-05 0005 Miami comprehensive sickle cell
center - Sickle cell clinic
P60HL- 17269-04 0039 National heart and blood vessel
research and demonstration center ■ Health care services
to patients in neighborhood clinics
ROlHL-18805-04 0004 Sudden cardiac death and the
onset of myocardial infarction - Sudden death survivors-
Clinical tollow-up and therapy (human)
P50HL-19157-02 0002 Studies in cystic librosis and
bronchiolitis ■ Clinical core
P60HL-20985-01 0001 Northern Calilornia sickle cell
center - Sickle cell anemia quality assurance program
ROlHL-22032-01
(human)
ROlHL-22567-01
method in man
NOlHV-12435-15
Cardiovascular events in hypertensives
Validation ol a cholesterol absorption
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
**Ori«nted significantly to above subject.
Therapy lor hypertension in the general
population (human)
** N01HV-53015-09 Establishment ol a lipid research clinic
(human)
HEALTH CARE FACILITIES, RESIDENTIAL
** P60HL15158-07 0027 Comprehensive sickle cell center -
Community advisory board-Nancy Cobb house
HEALTH CARE FACILITIES (SYSTEMS)
AUTOMATED
SEE BIOMEDICAL SYSTEMS AUTOMATED, HEALTH CARE
FACILITIES (SYSTEMS) AUTOMATED
HEALTH CARE FACILITIES (SYSTEMS)
INFORMATION SYSTEMS
SEE BIOMEDICAL SYSTEMS AUTOMATED, HEALTH CARE
FACILITIES (SYSTEMS) INFORMATION SYSTEMS
HEALTH (CARE) PERSONNEL ADJUNCT
SEE HEALTH SCIENCES PROFESSIONS, HEALTH (CARE)
PERSONNEL ALLIED
HEALTH CARE PROFESSIONAL PRACTICE,
GROUP PRACTICE, HMO
ROlHL-22380-01 Detroit hypertension control program
HEALTH CARE QUALITY
SEE ALSO DIAGNOSTIC QUALIH STANDARDS
SEE ALSO HEALTH SCIENCES PROFESSIONS, HEALTH
PERSONNEL PERFORMANCE
SEE ALSO HEALTH SOCIAL CONTROL
P60HL-17269-04 0039 National heart and blood vessel
research and demonstration center ■ Health care services
to patients in neighborhood clinics
P60HL-1729204 0030 Vermont Lung Center - Hospital
treatment of pneumonia
R25HL-18406-03 Adherence to hypertensive medical
regimens (human)
** P60HL-20985-01 0001 Northern Calilornia sickle cell
center - Sickle cell anemia quality assurance program
(contd)
M Grant has subprojects describing specilic research aspects.
See Appendix tor investigator's name and grant number.
HEA
HEALTH CARE SERVICES (GENERAL)
SEE ALSO CHILD HEALTH CARE (SERVICES)
SEE ALSO DIAGNOSTIC SERVICES
SEE ALSO FAMILY PLANNING
SEE ALSO HEALTH SERVICES DEMONSTRATION PROJECTS
SEE ALSO MENTAL HEALTH SERVICES
*• NOlHV-2293912 Hypertension detection and follow-up
program center
HEALTH CARE SERVICES, CASE FINDING AND
OUTREACH
SEE ALSO HEALTH CARE SERVICES, REFERRAL AND
CONSULTATION
P60HL-15157-07 0003 Comprehensive center tor sickle
cell disease - Public education
PeOHL-15160'07 0017 Center for sickle cell disease ■
Demonstration-Education, screening, counseling, patient
care
P60HL-1516207 0010 Comprehensive sickle cell center
Core program-Community outreach and education program
ROlHL-2221201 Alameda county high blood pressure
control program
ROlHL-22380-01 Detroit hypertension control program
HEALTH CARE SERVICES, COMMUNITY HEALTH
SERVICES
SEE ALSO SOCIAL SERVICES (GENERAL)
ROIHLI 1901-12 0001 Effects of metabolic surgery on
the hyperlipidemias - Partial ileal bypass (human)
M P60HL-15157-O7 Comprehensive center for sickle cell
disease
P60HL-15157-07 0001 Comprehensive center for sickle
cell disease Screening program (human)
P60HL-15157-07 0002 Comprehensive center for sickle
cell disease - Central data bank and research file
P60HL-15157-07 0003 Comprehensive center for sickle
cell disease - Public education
P60HL-15158-07 0027 Comprehensive sickle cell center -
Community advisory board -Nancy Cobb house
P60HL-15158-07 0028 Comprehensive sickle cell center -
Education
P60HL-15160-07 0003 Center for sickle cell disease -
Genetic counseling in hemoglobinopathies-Dimensions,
effectiveness
P60HL-15160-07 0017 Center for sickle cell disease ■
Demonstration-Education, screening, counseling, patient
care
** P60HL15162-07 0010 Comprehensive sickle cell center -
Core program -Community outreach and education program
** P60HL-1 5168-07 0002 Comprehensive sickle cell disease
center - Patient care
** P60HL-15168-07 00C3 Comprehensive sickle cell disease
center - Sickle cell education and training program
P60HL15168-07 0006 Comprehensive sickle cell disease
center • Core center
P60HL15169-05 0017 Support for center for sickle cell
disease - Study of the natural history of sickle cell disease
in the home
** P60HL1 5169-05 0021 Support for center for sickle cell
disease - Multidisciplinary module system for education,
screening and counseling
P60HL-15170-05 0001 Support for center for sickle cell
anemia - Adult clinical services
P60HL-15170-05 0003 Support for center for sickle cell
anemia - Adult services -Educational programs
** P60HL-1 5 170-05 0023 Support for center for sickle cell
anemia - Comprehensive sickle cell clinic
P60HL-15170-05 0030 Support for center for sickle cell
anemia • Adult services -Counseling program
** P60HL-1599606 0005 Cincinnati comprehensive sickle
cell center - Factors precipitating crises (human)
P60HL-1 5996-06 0006 Cincinnati comprehensive sickle
cell center - Education
P60HL-15996-06 0007 Cincinnati comprehensive sickle
cell center - Screening and counseling
P60HL-15999-05 0004 Miami comprehensive sickle cell
center ■ Education, screening and counseling
** P60HL-16005-05 0001 Comprehensive sickle cell center -
Demonstration -Community service component
P60HL- 16008-06 0011 Wayne State University
comprehensive sickle cell center - Education, screening and
counseling
** P60HL-1 7269-04 0039 National heart and blood vessel
research and demonstration center ■ Health care services
to patients in neighborhood clinics
•• P60HL-17292-04 0018 Vermont Lung Center • Group
patient education-Breathing workshop project
P50HL-18323-04 0035 SCOR hypertension center ■ Control
of high blood pressure at the work site
P50HL-1917102 0005 Pulmonary SCOR-Lung injury by
childhood infections - Chronic respiratory disease of
children in North Carolina
** P50HL-19190-02 0002 Pulmonary SCOR-Pathophysiology,
management of IRDS - Core-Demonstration and
dissemination
M P60HL-20985-01 Northern California sickle cell center
** P60HL-20985-01 0008 Northern California sickle cell
center - Demonstration community program-Patient
ambudsman
** P60HL-20985-01 0011 Northern California sickle cell
center - SNMA community education program
R18HL-2190601
reduction study
ROlHL-22212-01
control program
ROlHL-22380-01
ROlHL-22802-01
230
Stanford five city multifactor risk
Alameda county high blood pressure
Detroit hypertension control program
A rural mining community hypertension
control project (human)
M P60HL-23282-01 Comprehensive hospital/community sickle
cell center
P60HL-23282-01 9001 Comprehensive hospital/community
sickle cell center - Core -Institutionalization of education,
screening and counseling
** P60HL-2328201 9002 Comprehensive hospital/community
sickle cell center - Core -Model sickle cell service for
neighborhood health centers
N01HV12434-11 Therapy for hypertension in the general
population
NOlHV-12435-15 Therapy for hypertension in the general
population (human)
NOlHV-12436-15 Hypertension therapy in the general
population (human)
NOlHV-12442-14 Therapy for hypertension in the general
population (human)
NOlHV-82915-01 Therapy for hypertension in the general
population (human)
HEALTH CARE SERVICES, HOME CARE
P60HL-15169-05 0017 Support for center for sickle cell
disease Study of the natural history of sickle cell disease
in the home
P60HL-15169-05 0021 Support for center for sickle cell
disease - Multidisciplinary module system for education,
screening and counseling
P60HL-1600806 0011 Wayne State University
comprehensive sickle cell center - Education, screening and
counseling
R25HL-184 14-03 Hypertension-Family strategies for
patient adherence
ROlHL-19844-02 Behavioral control of essential
hypertension (human)
ROlHL-19946-03 Reduction of iron overload in
thalassemia (children, rabbits, dogs, monkeys)
P60HL-20985-01 0009 Northern California sickle cell
center - Patient services (children, adults)
ROlHL-21323-02 Raynaud's disease and temperature self-
regulation (human)
ROlHL-222 12-01 Alameda county high blood pressure
control program
HEALTH CARE SERVICES, MATERNAL AND
INFANT CARE
SEE ALSO HOSPITALS, NURSERY
P60HL-1 51 58-07 0012 Comprehensive sickle cell center -
Clinical services-Pediatric patients
P60HL-15162-07 0001 Comprehensive sickle cell center -
Core program -Patient care
HEALTH CARE SERVICES, PATIENT CARE
SEE ALSO BIOMEDICAL SYSTEMS AUTOMATED, COMPUTER
ASSISTED PATIENT CARE
** POlHL-12373-10 0020 Cardiopulmonary physiology and
pathophysiology Hospitalization and patient care
ROlHL-17604-03 Wearable blood pressure and ECG
recording system
POlHL-21016-02 0017 Sickle cell anemia and other
hemoglobinopathies - The hereditary clinic core
NOlHR-62934-02 Evaluate continuing education in
pulmonary medicine
HEALTH CARE SERVICES, PATIENT CARE,
EMERGENCY CARE
SEE ALSO HEART RESUSCITATION
SEE ALSO HOSPITALS, INTENSIVE CARE UNITS
SEE ALSO RESPIRATORY ASSIST AND OXYGEN
ADMINISTRATION, ARTIFICIAL RESPIRATION
P60HL151 58-07 0012 Comprehensive sickle cell center •
Clinical services-Pediatric patients
P60HL-151 60-07 0017 Center for sickle cell disease -
Demonstration-Education, screening, counseling, patient
care
Pe0HL-I5168-07 0002 Comprehensive sickle cell disease
center - Patient care
P60HL-151 70-05 0001 Support for center for sickle cell
anemia - Adult clinical services
P60HL-16008-06 0001 Wayne State University
comprehensive sickle cell center - Patient care system
(children, adults)
P60HL-17269-04 0036 National heart and blood vessel
research and demonstration center - Public education
P60HL-20985-01 0008 Northern California sickle cell
center • Demonstration community program-Patient
ambudsman
P60HL-20985-01 0009 Northern California sickle cell
center ■ Patient services (children, adults)
HEALTH CARE SERVICES, PATIENT CARE,
HOSPITAL PATIENTS
SEE ALSO HOSPITALS, OUTPATIENT FACILITIES
P50HL-14138-05 0014 Center for research on
atherosclerosis - Core biostatistics laboratory
P60HL-15996-06 0008 Cincinnati comprehensive sickle
cell center - Patient care (children, adults)
HEA
** P50HL-17667-04 0038 Study of ischemic heart disease -
Clinical core unit
ROlHL'22567-01 Validation of a cholesterol absorption
method in man
HEALTH CARE SERVICES, PATIENT CARE, POST-
HOSPITALIZATION CARE
ROlHL-21674-01 Development of automatic implanted
defibrillator (dogs, cattle)
HEALTH CARE SERVICES, PATIENT CARE
MANAGEMENT
SEE ALSO HEALTH CARE SERVICES, PATIENT CARE
PERSONNEL AHITUDES
SEE ALSO HEALTH CARE SERVICES, PATIENT-PROFESSIONAL
RELATIONS
POlHL-10436-13 0001 A multidisciplinary study of
congenital heart disease - Assessment of the outlook for
children with congenital heart disease
** POlHL-12738-10 0071 Physiologic pharmacology and Its
clinical applications - lABP patient management In
ventricular power failure (human)
POlHL-12738-10 0092 Physiologic pharmacology and its
clinical applications - Subendocardial ischemia following
open heart surgery (human)
P50HL-14159-08 0024 Specialized center of research in
hypertension - Core resources (clinical, animal models)
P50HL-14214-07 0033 Newborn lung center for hyaline
membrane disease - Statistical modeling, predictive
classification in clinical management of HMO
R25HL'17056-01 Improving patient compliance through
nursing action
** P60HL-17269-04 0039 National heart and blood vessel
research and demonstration center Health care services
to patients in neighborhood clinics
P60HL-17269-04 0047 National heart and blood vessel
research and demonstration center - Evaluation of
competency-based educational model
** P50HL- 17665-04 0026 Study of ischemic heart disease -
Anesthesia-Myocardial ischemia and hemodynamics in
coronary disease (human)
" P50HL-17670-04 0001 Study of ischemic heart disease -
Data management
R25HL-18424-03 Blood pressure education in an industrial
setting (human)
P50HL19190-02 0002 Pulmonary SCOR-Pathophysiology,
management of IRDS - Core-Demonstration and
dissemination
Alameda county high blood pressure
ROlHL-22212-01
control program
NOlHR-72972-01
NOlHV-22945-11
Self-management for asthmatic children
Cooperative hypertension detection and
follow-up study (human)
NOlHV-53006-06 Evaluation of model VII left ventricular
assist device (human)
HEALTH CARE SERVICES, PATIENT CARE
MANAGEMENT, COMPREHENSIVE CARE
SEE ALSO HEALTH CARE SERVICES, PATIENT CARE, POST-
HOSPITALIZATION CARE
SEE ALSO HEALTH CARE SERVICES, PATIENT CARE
MANAGEMENT, PLANNING
M P60HL-15157-07 Comprehensive center for sickle cell
disease
M P60HL-15158-07 Comprehensive sickle cell center
** P60HL-151 58-07 0011 Comprehensive sickle cell center -
Clinical services-Adult patients
** P60HL-1 5 158-07 0012 Comprehensive sickle cell center -
Clinical services-Pediatric patients
M PeOHL-15160-07 Center for sickle cell disease
** P60HL-1 5160-07 0017 Center for sickle cell disease -
Demonstration-Education, screening, counseling, patient
care
M P60HL-15162-07 Comprehensive sickle cell center
** P60HL-15162-07 0001 Comprehensive sickle cell center -
Core program-Patient care
P60HL-15162-07 0010 Comprehensive sickle cell center •
Core program-Community outreach and education program
M P60HL-15168-07 Comprehensive sickle cell disease center
P60HL-15168-07 0003 Comprehensive sickle cell disease
center - Sickle cell education and training program
** P60HL-15168-07 0006 Comprehensive sickle cell disease
center - Core center
P60HL-15ie8-07 0010 Comprehensive sickle cell disease
center - Sickle cell center project (children)
P60HL-15169-05 0017 Support for center for sickle cell
disease - Study of the natural history of sickle cell disease
in the home
M P60HL-15170-05 Support for center for sickle cell anemia
•* P60HL-15170-05 0001 Support for center for sickle cell
anemia - Adult clinical services
P60HL-15170-05 0002 Support for center for sickle cell
anemia - Adult services-Testing programs
** P60HL-15170-05 0006 Support for center for sickle cell
anemia - Pediatric services-Comprehensive clinic
** P60HL-1 5 170-05 0023 Support for center for sickle cell
anemia - Comprehensive sickle cell clinic
M PeOHL-15996-06 Cincinnati comprehensive sickle cell
center
P60HL-159960e 0006 Cincinnati comprehensive sickle
cell center - Education
** P60HL-1 5996-06 0007 Cincinnati comprehensive sickle
cell center - Screening and counseling
(contd)
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
**Ohented significanthr to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
J
Therapy tor hypertension in the general
HEA
" P60HL I&99606 0008 Cincinnsti comprthtnsivd sicKle
cell centtr P>tl«nt care (children, adults)
P60HI 159990b 0004 Miami comprehensive sicKle cell
center Education, screenmi and counseling
•■ P60HI 1599905 0005 Miami comprehensive sickle cell
center Sickle cell clinic
P60HI 16005 05 0001 Comprehensive sickle cell center
Demonstration Community service component
** P60HL 16005 05 0018 Comprehensive sickle cell center
Comprehensive study- Natural hutoiY of sickle cell disease
In adults (human)
M P60HI 16008 06 Wayne State University comprehensive
sickle cell center
** P60HL 16008 06 0001 Wayne State University
comprehensive sickle cell center Patient care system
(children, adults)
P60HL- 17292 04 0009 Vermont Lung Center Controlled
clinical trials on a clinical core unit (human)
P50HL1915702 0002 Studies in cystic fibrosis and
bronchiolitis Clinical core
*• ROIHI 20637 02 Recovery atler heart surgery Bio
behavioral (actors (human)
M P60HL-2098501 Northern California sickle cell center
P60HL20985 01 0008 Northern California sickle cell
center Demonstration community program Patient
ambudsman
** P60HL-20985 01 0009 Northern California sickle cell
center Patient services (children, adults)
** ROlHl 2298201 Multicenter postcoronary risk
stratification program (human)
M P60HL-2328201 Comprehensive hospital/community sickle
cell center
** N01HV12434-11
population
** NOlHV-1243615 Hypertension therapy in the general
population (human)
NOlHV-1244214 Therapy for hypertension in the general
population (human)
NOlHV-53006-06 Evaluation of model VII left ventricular
assist device (human)
** NOlHV-82915-01 Therapy for hypertension in the general
population (human)
HEALTH CARE SERVICES, PATIENT CARE
MANAGEMENT, COMPREHENSIVE CARE,
FAMILY MEDICINE
SEE ALSO HEALTH CARE SERVICES, HOME CARE
SEE ALSO HEALTH CARE SERVICES, MATERNAL AND INFANT
CARE
SEE ALSO PSYCHOTHERAPY, FAMILY THERAPY
** P60HL-15168-07 0002 Comprehensive sickle cell disease
center ■ Patient care
P60HL- 15996-06 0008 Cincinnati comprehensive sickle
cell center - Patient care (children, adults)
P60HL-1 7265-04 0001 Community blood resource center
support - Demonstration and evaluation
HEALTH CARE SERVICES, PATIENT CARE
MANAGEMENT, PLANNING
** P60HL- 17292-04 0013 Vermont Lung Center - Regional
management of respiratory disease program
** P60HL-1 7292-04 0030 Vermont Lung Center ■ Hospital
treatment of pneumonia
P50HL-1918702 0012 Pediatric pulmonary SCOR -Hyaline
membrane disease - Resource requirements, economic
consequence of HMD and recurrent apnea
ROlHL-22380-01 Detroit hypertension control program
P60HL-23282-01 9002 Comprehensive hospital/community
sickle cell center - Core -Model sickle cell service for
neighborhood health centers
** NOlHV-72984-03 High blood pressure control program
(human)
NOlHV-72986-02
(human)
NOlHV-72987-02
(human)
NOlHV-72989-02
(human)
NOlHV-72990-00
(human)
High blood pressure control program
High blood pressure control program
High blood pressure control program
High blood pressure control program
HEALTH CARE SERVICES, PATIENT CARE
PERSONNEL ATTITUDES
P60HL-1 7292-04 0030 Vermont Lung Center - Hospital
treatment of pneumonia
HEALTH CARE SERVICES, PATIENT-
PROFESSIONAL RELATIONS
P60HL-15168-07 0003 Comprehensive sickle cell disease
center - Sickle cell education and training program
R25HL-17056-01 Improving patient compliance through
nursing action
P60HL-17269-04 0039 National heart and blood vessel
research and demonstration center - Health care services
to patients in neighborhood clinics
P60HL-1 7269-04 0047 National heart and blood vessel
research and demonstration center - Evaluation of
competency-based educational model
P60HL-20985-01 0008 Northern California sickle cell
center - Demonstration community program -Patient
ambudsman
231
HEALTH CARE SERVICES, PHYSICAL THERAPY
SFE ALSO IHIRAPY, HYUROIHIRAHY
POIHI 10539 12 0031 Pathophysiology of circulation
Post myocardial infarction care Psychological aspects
(human)
POIHL 10539 12 0064 Pathophysiology of circulation
Eiercise physiology and pathophysiology (human)
** ROIHI 1375408 Postoperative thromboembolism in
surgical patients (human)
HOIHL 16292 05 0009 Surgery and nonobstructive
coronary insufficiency Exercise and supply demand
balance (human)
P60HL 17292 04 0009 Vermont Lung Center Controlled
clinical trials on a clinical core unit (human)
P60HL 17292 04 0018 Vermont Lung Center Group
patient education Breathing workshop proiect
ROIHL 17578 04 Exercise performance in children with
heart disease
ROIHL 17993 04 0004 Ventricular dynamics from
surgically inserted markers Exercise training following
coronary artery bypass graft surgery (human)
** ROIHL 2018701 Evaluation of exercise cardiac
rehabilitation program (40 55 year old men)
ROlHL-21578-01
adolescent
" R23HL2195401
cystic fibrosis
ROlHL-22215 01
heart disease (human)
•* P60HL23282 01 0003 Comprehensive hospital/community
sickle cell center Treatment of sickle cell ulcers with
physical therapy and vitamin E (human)
HEALTH CARE SERVICES, PHYSICAL THERAPY,
ELECTROTHERAPY
ROlHL-13754-08 Postoperative thromboembolism in
surgical patients (human)
HEALTH CARE SERVICES, REFERRAL AND
CONSULTATION
P60HL1 51 58-07 0009 Comprehensive sickle cell center -
Counseling and social services
P60HL 15162-07 0010 Comprehensive sickle cell center •
Core program -Community outreach and education program
P60HL-151 62-07 0011 Comprehensive sickle cell center •
Core program -Genetic counseling and diagnostic screening
P60HL-15168-07 0001 Comprehensive sickle cell disease
center - Screening program (human)
P60HL 15168-07 0002
center - Patient care
Effect of exercise upon the hypertensive
Exercise conditioning in patients with
Effects of exercise training in ischemic
P60HL-151 68-07 0006
center - Core center
P60HL-151 70-05 0001
Comprehensive sickle cell disease
Comprehensive sickle cell disease
Support for center for sickle cell
anemia - Adult clinical services
P60HL-15170-05 0023 Support for center for sickle cell
anemia - Comprehensive sickle cell clinic
P60HL 15999-05 0004 Miami comprehensive sickle cell
center - Education, screening and counseling
P60HL-16005-05 0001 Comprehensive sickle cell center -
Demonstration-Community service component
P60HL-16008-06 0011 Wayne State University
comprehensive sickle cell center - Education, screening and
counseling
P60HL-20985-01 0008 Northern California sickle cell
center - Demonstration community program-Patient
ambudsman
P60HL-20985-01 0009 Northern California sickle cell
center - Patient services (children, adults)
ROlHL-222 12-01 Alameda county high blood pressure
control program
ROlHL-22380-01 Detroit hypertension control program
HEALTH CARE SERVICES, REHABILITATION
NONPSYCHOSOCIAL
SEE ALSO HEALTH CARE SERVICES, REHABILITATION
VOCATIONAL
SEE ALSO MENTAL HEALTH SERVICES, REHABILITATION
PSYCHOSOCIAL
SEE ALSO OCCUPATIONS. VOCATIONAL GUIDANCE
P60HL-151 69-05 0021 Support for center for sickle cell
disease - Multidisciplinar^ module system for education,
screening and counseling
P60HL-17292-04 0018 Vermont Lung Center - Group
patient education-Breathing workshop project
** ROlHL-17993-04 0004 Ventricular dynamics from
surgically inserted markers - Exercise training following
coronary artery bypass graft surgery (human)
HEALTH CARE SERVICES, REHABILITATION
VOCATIONAL
P60HL-15162-07 0001 Comprehensive sickle cell center -
Core program-Patient care
P50HL-I51 70-05 0023 Support for center for sickle cell
anemia - Comprehensive sickle cell clinic
P60HL-15996-06 0008 Cincinnati comprehensive sickle
cell center - Patient care (children, adults)
P60HL-16008-06 0011 Wayne State University
comprehensive sickle cell center - Education, screening and
counseling
HEALTH CARE SERVICES, SHARED SERVICES
** NOlHB-62967-03 Blood banking services on a regional
basis
HIA
HEALTH CARE (SERVICES)(RE$OURCES)
ANALYSIS AND EVALUATION
SK Also III Aim CAHI 011*1 HY
Sit AlSOHfAIIH CARI CI RVK.I ',)(«( SOUHCFS) PIANNINC
SEE ALSO HIAIIH SCIINCIS FROflSSIONS. HfAllH
PfRSONNfl PfHfORMANCf
SEF ALSO HfAlTH SCIINtfS Rt SI ARCH ANALYSIS
EVALUAIION PIANNINC
P60HL 1516007 0003 Center (or sickle cell disease
Genetic counseling in hemoglobinopathies Dimensiont.
effectiveness
P60HL 15996 06 0009 Cincinnati comprehensive sickle
cell center Insurance coverage of persons with tickle cell
trait and disease
P60HL 16005 05 0001 Comprehensive sickle cell center ■
Demonstration Community service component
P60HL 16008 06 0001 Wayne State University
comprehensive sickle cell center Patient care system
(children, adults)
** P60HL 1726504 0001 Community blood resource center
support Demonstration and evaluation
*• P60HL 17269 04 0039 National heart and blood vessel
research and demonstration center Health care services
to patients in neighborhood clinics
P60HL 17292 04 0013 Vermont Lung Center Regional
management of respiratory disease program
P60HL 17292 04 0023
information resources
P50HL- 17670 04 0001
Data management
** P50HL19187 02 0012 Pediatric pulmonary SCOR Hyaline
membrane disease Resource requirements, economic
consequence of HMD and recurrent apnea
** P60HL-20985-01 0001 Northern Calitornia sickle cell
center Sickle cell anemia quality assurance program
Vermont Lung Center Health
Study of ischemic heart disease
ROIHL 2221201
control program
ROlHL-22380-01
NOlHV-72984 03
(human)
NOlHV-72986-02
(human)
NOlHV-72987 02
(human)
NOlHV-72989-02
(human)
NOIHV 72990-00
(human)
Alameda county high blood pressure
Detroit hypertension control program
High blood pressure control program
High blood pressure control program
High blood pressure control program
High blood pressure control program
High blood pressure control program
HEALTH CARE (SERVICES)(RESOURCES)
PLANNING
P60HL-17292-04 0023 Vermont Lung Center Health
information resources
** ROlHL-17993-04 0010 Ventricular dynamics from
surgically inserted markers - Postoperative cardiovascular
visualization (human)
HEALTH CARE (SERVICES)(RESOURCES)
PLANNING, COMPREHENSIVE
ROlHL-22802-01 A rural mining community hypertension
control project (human)
HEALTH CARE
(SERVICES)(RESOURCES)PLANNING,
REGIONAL MEDICAL PLANNING
NOlHB-62967-03 Blood banking services on a regional
basis
POlHL-09011-15 0017 A research and resource program
in blood - Operations research laboratory
ROIHL- 15047-06 Digital computer analysis of the
electrocardiogram (human)
M P60HL-17265-04 Community blood resource center support
M P60HL- 17292-04 Vermont Lung Center
P60HL-17292-04 0009 Vermont Lung Center - Controlled
clinical trials on a clinical core unit (human)
** P60HL-1 7292-04 0013 Vermont Lung Center - Regional
management of respiratory disease program
" P60HL-17292-04 0030 Vermont Lung Center - Hospital
treatment of pneumonia
** P60HL-17292-04 0031 Vermont Lung Center - Regional
respiratory computer network
ROlHL-22380-01 Detroit hypertension control program
HEALTH CARE (SERVICES)(RESOURCES)
UTIUZATION
SEE ALSO HOSPITALS UTILIZATION
** P50HL-14236-05 0013 Prevention of premature
arteriosclerosis - Patient compliance
P60HL-16005-05 0001 Comprehensive sickle cell center -
Demonstration -Community service component
** P60HL-17269-04 0039 National heart and blood vessel
research and demonstration center - Health care services
to patients in neighborhood clinics
** ROlHL-18175-03 Drug taking for hypertension in a rural
community
NOlHR-72974-01 Self-management systems for asthmatic
children
HEALTH CARE (SERVICES)(REaOURCES)
UTILIZATION, APPOINTMENTS-VISITS
R25HL-18406-03 Adherence to hypertensive medical
regimens (human)
(contd)
•Excludes routine methodokigy OR covers only general proiects which preclude indexing at the specific level.
"•Oriented significantly to above subject.
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
HEA
R25HL-18414-03 Hypertension-Family strategies for
patient adherence
R25HL-18418-03 Role of a supporting partner in
adherence (human)
R25HL-18424-03 Blood pressure education in an industrial
setting (human)
HEALTH CARE (SERVICES)(RESOURCES)
UTILIZATION, AVAILABILITY AND
DISTRIBUTION OF SERVICES AND RESOURCES
P60HL-1 7269-04 0039 National heart and blood vessel
research and demonstration center - Health care services
to patients in neighborhood clinics
P50HL-19187-02 0012 Pediatric pulmonary SCOR-Hyaline
membrane disease ■ Resource requirements, economic
consequence of HMD and recurrent apnea
HEALTH ECONOMICS
" P50HL-19187 02 0012 Pediatric pulmonaof SCOR-Hyaline
membrane disease - Resource requirements, economic
consequence of HMD and recurrent apnea
HEALTH ECONOMICS, FUND RAISING
P60HL-15158 07 0027 Comprehensive sickle cell center ■
Community advisory board -Nancy Cobb house
HEALTH ECONOMICS, HEALTH CARE COSTS-
FINANCING
SEE ALSO HEALTH CARE (SERVICESXRESOURCES) PUNNING,
COMPREHENSIVE
SEE ALSO HEALTH INSURANCE
P60HL-1 7269-04 0039 National heart and blood vessel
research and demonstration center Health care services
to patients in neighborhood clinics
P50HL-17667-04 0001 Study of ischemic heart disease -
Natural history of ischemic heart disease (human)
R25HL-18424 03 Blood pressure education in an industrial
setting (human)
P50HL-I9187 02 0012 Pediatric pulmonary SCOR-Hyaline
membrane disease - Resource requirements, economic
consequence of HMD and recurrent apnea
" NOlHV-82913-00 Demonstration programs in hypertension
control in the v»ork setting (human)
HEALTH ECONOMICS, HEALTH CARE COSTS-
FINANCING, MEDICAL INDIGENCY
P60HL-20985C1 0008 Northern California sickle cell
center Demonstration community program-Patient
ambudsman
HEALTH EDUCATION
SEE EDUCATION, HEALTH EDUCATION
HEALTH FACILITIES (SYSTEMS) AUTOMATED
SEE BIOMEDICAL SYSTEMS AUTOMATED, HEALTH CARE
FACILITIES (SYSTEMS) AUTOMATED
HEALTH HAZARDS, ENVIRONMENTAL
SEE ENVIRONMENTAL HEALTH, CONTAMINATION (GENERAL)
HEALTH INSURANCE
SEE ALSO HEALTH ECONOMICS, HEALTH CARE COSTS-
FINANCING
** P60HL- 15996-06 0009 Cincinnati comprehensive sickle
cell center ■ Insurance coverage of persons with sickle cell
trait and disease
HEALTH MAINTENANCE ORGANIZATIONS
SEE HEALTH CARE PROFESSIONAL PRACTICE, GROUP
PRACTICE. HMO
HEALTH OCCUPATIONS EDUCATION
SEE EDUCATION, HEALTH OCCUPATIONS
HEALTH PERSONNEL PERFORMANCE
SEE HEALTH SCIENCES PROFESSIONS, HEALTH PERSONNEL
PERFORMANCE
HEALTH RECORD SYSTEMS, PATIENT (DISEASE)
REGISTRIES
ROlHL-04666-19 Artificially paced hearts-Technology,
physiology (human, dogs)
PDlHL-06835-17 0048 Cardiovascular disease -
Aldosterone producing adenoma prediction of curability
(human)
POlHL-1310809 0001 Clinical heart transplantation -
Therapy and prognosis (human)
R01HL-I388508 9002 Cystic fibrosis and pulmonary
disease - Computer core facility (human)
R01HL13974-07 Ventricular premature beats and sudden
coronary death (human)
P50HL-14138-05 0014 Center for research on
atherosclerosis - Core biostatistics laboratory
P50HL1415908 0023 Specialized center of research in
hypertension > Core computation
P50HL14214-07 0033 Newborn lung center for hyaline
membrane disease - Statistical modeling, predictive
classification in clinical management of HMD
P50HL-1421407 0036 Newborn lung center for hyaline
membrane disease • Core-Biomedical engineering
P50HL-14218-07 0012 Pulmonary SCOR-Newborn lung
center ■ Longitudinal study of RDS -Online fetal and
neonatal monitoring (tiuman)
232
P50HL1 5092-07 0002 Immune and fibrotic response to
occupational environments - Longitudinal study of
sandblasters silicosis (human)
P60HL-15157-07 0002 Comprehensive center for sickle
cell disease Central data bank and research file
P60HL-15160-07 0009 Center for sickle cell disease ■
Natural history of sickle cell disease (human)
P60HL151 69-05 0017 Support for center for sickle cell
disease - Study of the natural history of sickle cell disease
in the home
P5OHL-15389-07 0010 Pulmonary SCOR -Hypersensitivity
pneumonitis - Clinical study-Pulmonary lesions due to non-
invasive aspergillosis
P60HL-15996-06 0008 Cincinnati comprehensive sickle
cell center ■ Patient care (children, adults)
P60HL16005-05 9001 Comprehensive sickle cell center -
Core laboratory and counseling (human)
P60HL-16008-06 0012 Wayne State University
comprehensive sickle cell center - Central data
management -Computer system
ROlHL-16461-05 Late results of valve replacement-
Computer analysis (human)
P60HL-17269-04 0039 National heart and blood vessel
research and demonstration center ■ Health care services
to patients in neighborhood clinics
P50HL1765104 0033 Ischemic heart disease specialized
center of research Core facilities-Computer sciences
P50HL-17651-04 0034 Ischemic heart disease specialized
center of research Core facilities-Data management
P50HL-17667-04 0001 Study of ischemic heart disease -
Natural history of ischemic heart disease (human)
P50HL-17667-04 0038 Study of ischemic heart disease -
Clinical core unit
P5GHL-17667 04 0039 Study of ischemic heart disease -
Core human investigative laboratories
P50HL-17667-04 0041 Study of ischemic heart disease -
Biophysical sciences core -Data collection and retrieval
P50HL17667-04 0042 Study of ischemic heart disease -
Core -Central instrumentation and software
P50HL- 176 70-04 0001 Study of ischemic heart disease -
Data management
P50HL- 183 23-04 0034 SCOR hypertension center - Core-
Data management
ROlHL-18794-04 Prospective studies of conduction disease
(human)
ROlHL-18805-04 0001 Sudden cardiac death and the
onset of myocardial infarction - Predictive value of
maximum exercise stress testing (human)
ROlHL-18805-04 0004 Sudden cardiac death and the
onset of myocardial Infarction • Sudden death survivors-
Clinical follow-up and therapy (human)
ROlHL-18808-04 0001 Prediction and prevention of
sudden cardiac death - Prognostic significance of
premature ventricular contractions (human)
P01HL-197I7-02 0038 Response of the lung to injury -
Interstitial lung disease -Clinical, pathologic and
epidemiologic
ROIHL-19839-09 Factors in youth predisposing to chronic
diseases (former college students)
ROlHL-19864-03 Blood pressure of children and young
adults
ROlHL-20637-02 Recovery after heart surgery-Bio-
behavioral factors (human)
ROlHL-21971-01 Atherosclerotic disease and risk factors
in twins (human)
R18HL-22934-01 Behavorial approaches to adolescent
hypertension
NOlHV-12160-15 Establishment of a lipid research clinic
NOIHV-32974-09 Collaborative studies on coronary artery
surgery (human)
N01HV-62900-00 Study of breast cancer and reserpine use
(human)
HEALTH RECORDS
POlHL-113 10-12 0067 Mechanisms of cardiovascular
disease - Cardiac performance with measured
homodynamic variables (human)
P60HL-20985-01 0001 Northern California sickle cell
center - Sickle cell anemia quality assurance program
NOlHR-32900-09 Pilot study to standardize the
measurement of 'closing volume' (human)
N01HV-5297I06 Reexamination of Framingham heart
study cohort
NOlHV-53010-03 NAS-NRC twin registry
HEALTH RECORDS, CASE HISTORY
P60HL-I5160-07 0009 Center for sickle cell disease -
Natural history of sickle cell disease (human)
P60HL-16008-06 O0O9 Wsyre Stale Uri- ':r;.y
comprehensive sickle cell center Natural history of sickle
cell anemia (human)
ROlHL-22378-01 Psyco-somatic predictors of CHD in
adolescence (human)
NOlHR-72973-01 Health education and attitudes of family
toward asthmatic children
NOlHV-42902-08 Epidemiological studies of coronary heart
disease (human)
HEA
ROlHL-10582-12 Thrombosis and hemostasis -Analysis,
methods and standards (human, cattle, venom)
ROlHL-13885-08 9002 Cystic fibrosis and pulmonary
disease - Computer core facility (human)
P50HL-14138-05 0014 Center for research on
atherosclerosis ■ Core biostatistics laboratory
P50HL-14159-08 0023 Specialized center of research in
hypertension - Core computation
P50HL-14214-07 0036 Newborn lung center for hyaline
membrane disease - Core-Biomedical engineering
P50HL-142I8-07 0012 Pulmonary SCOR-Newborn lung
center - Longitudinal study of RDS -On-line fetal and
neonatal monitoring (human)
ROlHL-15047-06 Digital computer analysis of the
electrocardiogram (human)
** P60HL-15157 07 0002 Comprehensive center for sickle
cell disease - Central data bank and research file
P60HL-15160-07 0009 Center for sickle cell disease -
Natural history of sickle cell disease (human)
P60HL 16005-05 0018 Comprehensive sickle cell center -
Comprehensive study-Natural history of sickle cell disease
in adults (human)
P60HL 1600806 0012 VKayne State University
comprehensive sickle cell center - Central data
management -Computer system
" ROlHL-16461 05 Late results of valve replacement-
Computer analysis (human)
P60HL-1 7269-04 0027 National heart and blood vessel
research and demonstration center - Non-invasive
evaluation of cardiac function-lschemic heart disease
(human, dog)
P50HL-17651-04 0034 Ischemic heart disease specialized
center of research ■ Core facilities-Data management
** P50HL-1766504 0018 Study of ischemic heart disease -
Computer correlation of data-Patients with ischemic heart
disease
P50HL- 17665-04 0030 Study of ischemic heart disease -
Data management
** P50HL-17670-04 0001 Study of ischemic heart disease -
Data management
** P50HL- 17682-04 0009 Study of ischemic heart disease -
Computer core unit
P50HL-18318-03 0001 Pathogenesis and complications of
hypertension - Core clinical program
P50HL-18323-04 0035 SCOR hypertension center - Control
of high blood pressure at the work site
ROlHL-18800-04 Prospective study of resuscitated sudden
death victims (human)
ROlHL-18805-04 0001 Sudden cardiac death and the
onset of myocardial infarction - Predictive value of
maximum exercise stress testing (human)
ROlHL-19839-09 Factors in youth predisposing to chronic
diseases (former college students)
ROlHL-21010-02 Glycemia, other traits and CV death in
40,000 persons
ROlHL-2108802 Genetic patterns in deaths from Ml and
stroke in Utah
HEALTH RESOURCES-SERVICES PLANNING
SEE HEALTH CARE (SERVICESXRESOURCES) PUNNING
HEALTH RESOURCES-SERVICES UTILIZATION
SEE HEALTH CARE (SERVICES)(RESOURCES) UTILIZATION
HEALTH SCIENCES MANPOWER
SEE HEALTH SCIENCES PROFESSIONS, HEALTH SCIENCES
MANPOWER
HEALTH SCIENCES MANPOWER DATA AND
REGISTRIES
SEE HEALTH SCIENCES PROFESSIONS, HEALTH SCIENCES
MANPOWER DATA AND REGISTRIES
HEALTH SCIENCES PROFESSIONS, HEALTH
(CARE) PERSONNEL ALLIED
SEE ALSO EDUCATION, HEALTH OCCUPATIONS. ALLIED
SEE ALSO MENTAL HEALTH PERSONNEL ADJUNCT
R25HL-18414-03 Hypertension-Family strategies for
patient adherence
ROlHL-22212-01 Alameda county high blood pressure
control program
P60HL-23282-01 9001 Comprehensive hospital/community
sickle cell center - Core-lnstitutionalization of education,
screening and counseling
HEALTH SCIENCES PROFESSIONS, HEALTH
PERSONNEL PERFORMANCE
P60HL15160-07 0003 Center for sickle cell disease ■
Genetic counseling in hemoglobinopathies-Dimensions,
effectiveness
R25HL-17056-01 Improving patient compliance through
nursing action
P60HL-1729204 0030 Vermont Lung Center - Hospital
treatment of pneumonia
P60HL-23282-01 9001 Comprehensive hospital/community
sickle cell center - Core-lnstitutionalization of education.
screening and counseling
HEALTH RECORDS (SYSTEMS) AUTOMATED
ROlHL-04666-19 Artificially paced hearts-Technology.
physiology (human, dogs)
POlHL-0901115 0017 A research and resource program
in blood - Operations research laboratory
•Excludes routine methodotogy OR covers only general projects which preclude indexing at the specific level.
•"Oriented significantly to above subject.
HEALTH SCIENCES PROFESSIONS, HEALTH
SCIENCES MANPOWER
SEE ALSO RESEARCH MANPOWER REVIEW COMMITTEE
NOlHV-53008-07 Left ventricular assist device-Clinical
evaluation (human)
(contd)
lescribing specific research aspects.
M Grant has subproji
See Appendix tor investigator's name and grant number
HEA
HEALTH SCIENCES PROFESSIONS, HEALTH
SCIENCES MANPOWER DATA AND
REGISTRIES
" ROIHI. Ibbl4 04 Htitdity and oxyignttlecU on health ol
heart lungs (South America)
HEALTH SCIENCES PROFESSIONS, NURSE
PRACTITIONERS
P60HL 1599905 0005 Miami compiehensive sickle cell
center Sickle cell clinic
P60HI 16008 06 0001 Wayne State University
comprehensive sickle cell center - Patient care system
(children, adults)
ROIHL 2221? 01 Alameda county high blood pressure
control program
HEALTH SCIENCES PROFESSIONS, NURSES
SEF ALSO EDUCATION, HEALTH OCCUPATIONS, NURSING
R25HI 17056 01 Improving patient compliance through
nursing action
HEALTH SCIENCES PROFESSIONS, PHYSICIANS
SEE ALSO EDUCATION, HEALTH OCCUPATIONS, MEDICAL
P60HL 17269 04 0047 National heart and blood vessel
research and demonstration center Evaluation of
competency based educational model
*• NOlHR-62934 02 Evaluate continuing education in
pulmonary medicine
HEALTH SCIENCES PROFESSIONS EDUCATION
SEE EDUCATION, HEALTH OCCUPATIONS
HEALTH SCIENCES RESEARCH (GENERAL)*
NOlHB-4297112 Chimpanzees for hepatitis research
POlHL-04664'18 0005 Cardiovascular and lung dynamics
Applications of current research, equipment and
techniques
R01HL08696-15 0018 Orthotopic heart transplantation ■
Training in cardiac transplantation
** R01HL10880-13 Purification of human erythropoietin lor
research use
** P01HL14985-07 0016 Adaptation to hypoxia •
Administrative core
P01HL1857503 0009 Mechanisms of vascular changes
in hypertension - Administrative core
" POlHL-19737-02 0015 Cellular and molecular aspects of
respiratory physiology ■ Administrative core unit
POlHL-2099302 0013 Population dynamics of arterial
cells in atherogenesis - Administration-Core
POlHL-21016-02 0019 Sickle cell anemia and other
hemoglobinopathies Administration core
** N01HV-22915I1 Establishment of lipid research clinic
** NOlHV-22916-16 Establishment of a lipid research clinic
** NOlHV-6295705 Coordinating center model for NHLI
clinical trials
HEALTH SCIENCES RESEARCH ANALYSIS-
EVALUATION-PLANNING
SEE ALSO HEALTH CARE (SERVICES)(RESOURCES) ANALYSIS
AND EVALUATIOf<
NOlHB-7298203 Statistical coordinating center for sickle
cell disease
P50HL-17667-04 0044 Study of ischemic heart disease -
Core-Data management and analysis
HEALTH SERVICES DEMONSTRATION PROJECTS
M P60HL-15157-07 Comprehensive center for sickle cell
disease
M P60HL-15160-07 Center for sickle cell disease
** P60HL-15160-07 0017 Center for sickle cell disease -
Demonstration -Education, screening, counseling, patient
care
M P60HL-15162-07 Comprehensive sickle cell center
M P60HL15168-07 Comprehensive sickle cell disease center
M P60HL-15996-06 Cincinnati comprehensive sickle cell
center
** P60HL-1600505 0001 Comprehensive sickle cell center -
Demonstration-Community service component
** P60HL- 17265-04 0001 Community blood resource center
support - Demonstration and evaluation
M P60HL- 17269-04 National heart and blood vessel research
and demonstration center
M P60HL-17292-04 Vermont Lung Center
** P60HL-2098501 0008 Northern California sickle cell
center - Demonstration community program -Patient
ambudsman
** R18HL-21906-01 Stanford five city multifactor risk
reduction study
** ROlHL-22380-01 Detroit hypertension control program
** P60HL-23282-01 9001 Comprehensive hospital/community
sickle cell center - Core-lnstitutionalization of education,
screening and counseling
** P60HL-23282-01 9002 Comprehensive hospital/community
sickle cell center • Core -Model sickle cell service for
neighborhood health centers
** NOlHV-82913-00 Demonstration programs in hypertension
control in the work setting (human)
HEALTH SOCIAL CONTROL
SEE ALSO HEALTH CARE QUALITY
NOlHB-62967-03 Blood banking services on a regional
basis
POlHL-0901115 0022 A research and resource prosram
in blood - Cryopreservation of blood components (human)
333
HEALTH SURVEYS
Sff POPUIAIION SURVIYS, HIAITH SURVEYS
HEARING DISORDERS
SEE EAR DISORDERS. HEARING DISORDERS
HEART
SEE ALSO CARDIOVASCULAR AGENTS. CARDIOTONIC AND
CARDIOPROTECTIVE DRUGS (GfNERAl)
SEE ALSO CARDIOVASCULAR SURGERY, CIRCULATORY ASSIST
POIHL 06312 17 0052 Surgical cardiology Assay of
metabolic variables of rat heart
*• ROIHL 09364 14 Ion transport by heart mitochondria
(cattle, rat. rabbit)
" ROIHL 10503 13 Cardiac ion transport and ultrastructure
(rats, guinea pigs, rabbits)
ROIHL 10940 13 Lipid transport (rabbits, cattle, chickens)
** POIHL 11310 12 0102 Mechanisms of cardiovascular
disease Cardiac membrane and ion mobility (dogs)
ROIHL 1303508 Heart mitochondrial malate
dehydrogenase regulation
POIHL 1438807 0155 Regulation of the circulation in
pathological states Cardiopulmonary afferent activity,
carotid chemo baroreceptor reflexes
ROIHL 1448308 Energy conservation in heart
mitochondria (cattle. E coli. human)
** ROIHL 14706 07 Fetal hearts in organ culture (mice)
ROIHL 15958-06 X ray diffraction analysis of thrombin
and neurotoxin
ROIHL 16577 04 Lipoprotein lipase chemistry and function
(rats, cattle, human)
R01HL17404 05 Immunologic mechanisms in heart
disease (mice)
ROIHL 17559-03 Structural elucidation of heart
cytochrome-C oxidase
P50HL-17682-04 0023 Study of ischemic heart disease -
Core cell and organ culture laboratory (mice)
ROlHL-17826-04 Oxygen delivery to tissue (rat, dog)
ROlHL-18038-03 Structure and function of heart
mitochondria (cattle)
ROIHL 18199-03 Effects of ions on vascular reactivity
ROlHL-18272-03 Heart adenyl cyclase complex (beef
heart)
ROIHL 18601-01 Regulation of neurotransmitter release by
adenosine (rats)
R01HL-1870S-03 Regulation of plasma triglyceride
metabolism (rats)
" ROlHL-1939403 Biochemistry and regulation of taurine in
the heart (rats, guinea pigs, cats)
POlHL-20984-02 9002 Cellular mechanisms in cardiac
hypertrophy - The heart in organ culture
** ROlHL-21 172-02 Regional oxygen consumption of heart
and other organs (animals)
** ROlHL-22136-02 Histamine and cardiac adenyl cyclase
ROlHL-22265-02 Isozymes of heart glutamate aspartate
transaminase (swine, ducks)
** R23HL-22775-01 Muscarinic receptors in the developing
heart (chick embryo)
** R23HL-22959-01 Heart development in inherited
cardiomyopathy (hamsters)
HEART, ATRIA
ROlHL-044 57-20 Cellular aspects of active transport (fish,
rabbits, anurans. turtles)
POlHL-06285-18 0180 Cardiovascular-respiratory
physiology and biochemistry - Vagal C-fibers and their
influence on visceral and somatic function (animals)
♦* P01HL06835-17 0043 Cardiovascular disease - Left
atrial receptor activity by the sympathetic nervous system
(dogs)
POlHL-08682-15 0016 Regulation of the cardiovascular
system - Shifting cardiac pacemakers and AV nodal
activation (dog)
POlHL-08682-15 0027 Regulation of the cardiovascular
system - Cardiac mechanoreceptors-Reflex regulation of
renal function (dogs)
POlHL-1 1307-12 9002 Biophysical studies in pediatric
cardiology - Biomedical engineering
** POlHL-1 13 1012 0060 Mechanisms of cardiovascular
disease - Effect of left atrium on the circulation -Simulation
POlHL-1 13 10-12 0089 Mechanisms of cardiovascular
disease - Structure and function in myocardial contraction
(dogs)
** ROlHL-12486-10 Structure-function correlation in the
atrium (rabbits)
" ROIHL 13623-08 Atrial receptors (dogs)
ROlHL-13920-07 Expanding the role of surgery of atrial
dysrhythmias (dogs)
POlHL-14388-07 0213 Regulation of the circulation in
pathological states - Regulation of the heart and peripheral
circulation in heart failure
POlHL-14388-07 0218 Regulation of the circulation in
pathological slates - Regional myocardial dyskincsis -Cause
assessment and reduction (dogs)
** P01HL15194-07 0004 Pathophysiology of
cardiopulmonary dysfunction - Specialized electrophysiology
fibers-Electrogenic basis of glycosides (mammals)
ROlHL-15694-06 Pulmonary factors in circulatory
regulation
P50HL-17648-04 0018 Study of ischemic heart disease -
Myocardial damage-Infarction vectors recalled by
premature atrial stimulation
'Excludes routine methodology OR covers only general protects which preclude indexing at the specific level.
''Oriented significantly to above subject.
M Grant has subprojects describing si
See Appendix for investigator's name
Ht A
P'.OHI 1/648 04 00?« Mudy o( uchemir i. . i
ElectiophyMology of sympathetic innervation in Ir.-.ur
culture
POOHI 1/651 04 0023 lirhemic heart diteate ipaciali/ad
center of research Development of multipurpoM calhtlar
lor monitoring and electronic paring
■■ RTIMt 1942303 Catecholamine action on the heart (tati,
rats)
" ROIHL 199950? Sensory transduction in cardiac
mechanoreceptors (cats, frogs, rats)
ROIHL 20153 02 Intracellular pH and myocardial
electropharmacology (dogs, guinea pigs)
ROIHL 20864 01 Postnatal maturation of cardiovascular
regulatory system (minipig)
" ROIHL 21 145 02 Response of atria to hyperosmolalily
Mechanisms (rabbits)
ROIHL 21742 01 Frequency dependent drug actions in
cardiac muscle (rabbits)
ROIHL 2205001 Organization ol sui' nic oxidase in heart
" R23HL 2224502 Functional characteristics of atrial
receptors (rats)
HEART, CONDUCTION SYSTEM
SEE ALSO HEART DISORDERS. ARRHYTHMIA, HEART BLOCK
SEE ALSO HEART DISORDERS DIAGNOSIS.
ELECTROCARDIOGRAPHY'
SEE ALSO HEART FUNCTION. HEART RHYTHM
SEE ALSO NERVOUS SYSTEM AUTONOMIC. HEART
INNERVATION
ROlHL-05694 20 Functional pathology ol cardiovascular
disease (human)
** ROlHL-05883 18 0004 Rellex control ol resistance and
capacitance vessels Lett ventricular receptors with
nonmedullated vagal alfeients (cats)
POlHL-06285-18 0153 Cardiovascular respiratory
physiology and biochemistry - Myocardial mechanics and
pharmacology in isolated papillary muscle (animals)
POlHL-0628518 0212 Cardiovascular-respiratory
physiology and biochemistry Membrane structure and
function -Gap junction (bovine)
POlHL-06308-18 0039 Mechanisms and therapy of
circulatory disease ANS in regulation of electrophysiology-
Role of cyclic nulceotides (animals)
" ROlHL-07047-16 Comparative study of cardiac conduction
system (human, birds, mammals)
ROlHL-07605-16 Congenital heart disease research
program (human, dogs)
" ROlHL-08508-15 Cardiac conductivity and automaticity
(human, dogs, rabbits)
M POlHL-08682-15 Regulation of the cardiovascular system
POlHL-08682-15 0011 Regulation of the cardiovascular
system - Histochemistry and ultrastructure of heart
innervation (dogs, ground squirrels)
" P01HL08682-15 0016 Regulation of the cardiovascular
system Shifting cardiac pacemakers and AV nodal
activation (dog)
POlHL-08682-15 0017 Regulation of the cardiovascular
system • Neurally induced cardiac dysrhythmias (dog)
POlHL-08682-15 0018 Regulation of the cardiovascular
system ■ Functional implications of cardiac afferent nerves
(dogs)
ROlHL-10417-12 Multiple systems in electrocardiography
(human)
POlHL-10436-13 0001 A multidisciplinary study of
congenital heart disease - Assessment of the outlook for
children with congenital heart disease
ROlHL-10951-11 Neural control of the heart (dogs, rats)
" POIHLI 1307-12 0002 Biophysical studies in pediatric
cardiology - Cardiac extracellular electrophysiology (human.
dog. chimpanzee)
** POlHL-11310-12 0075 Mechanisms of cardiovascular
disease - Bipolar atrial electrograms from Bachmann's
bundle (dogs)
** POlHL-11310-12 0090 Mechanisms of cardiovascular
disease - Clinicopathological cardiovascular correlation
(human, animals)
ROlHL-13187-09 Central neural control of cardiovascular
function (cats)
" ROlHL-13306-08 Pharmacological control of cardiac
membrane currents (cattle, rabbits)
ROlHL-13349-06 Analysis of activation process in heart
muscle (guinea pigs, rabbits, human)
ROlHL-13920-07 Expanding the role of surgery of atrial
dysrhythmias (dogs)
** ROlHL-14713-06 Hypothermia and the heart (bats, guinea
pigs)
ROlHL-16329-04 Cardiac surgical effect on heart function
in infants (human)
" P50HL-1 7648-04 0016 Study of ischemic heart disease •
Intraventricular conduction-Effect of pacing on conduction
and automaticity
P50HL-17651-04 0022 Ischemic heart disease specialized
center of research - Electrophysiology-Mechanism and
pharmacology of arrhythmias (human, dog)
P50HL-17667-04 0030 Study of ischemic heart disease -
Computerized clinical data acquisition and processing
" P50HL-17667-04 0031 Study of ischemic heart disease -
Pathophysiology in ischemic heart disease (dog. cat, rabbit,
monkey)
?50HL-1766904 0013 Ischemic heart disease center
(SCOR) - Exercise in patients with ischemic heart disease
(contd)
pecifir research aspects,
and grant number.
Antiafrhythmic drug action on VMAZ of
HEA
P50HL17670-04 0008 Study of Ischemic fieart disease -
Surgical treatment of cardiac rhytfim disorders (human,
dogs)
P50HLI7670-04 0016 Study of ischemic heart disease •
Core pathology laboratory (human, dogs, monkeys)
P50HL-17682-04 0012 Study of ischemic heart disease -
Pathology core laboratory (human)
ROlHL-17993-04 0003 Ventricular dynamics from
surgically inserted markers - Effects of pharmacologic
agents on left ventricular dynamics (human)
** R01HL18398-D4 Mechanisms of delayed and asymetric
ventricular conduction (human, dogs)
R01HL18517-03 Intrinsic innervation of the heart (dogs)
** R01HL1879404 Prospective studies of conduction disease
(human)
** R01HL19639-02 Permeability transients of carriers.
channels and heart
** ROlHL-20077-02 External cardiac stimulation with
microwave radiation (dogs)
ROlHL-20230-02 Analysis of the action potential of
cardiac muscle (sheep)
ROlHL-20558 02 Cardiac electrophyslology-Effects of Ions
and drugs
ROlHL-21672 01
cardiac cells
ROlHL-21922-01 Transient currents Induced by
strophanthidin in the heart
R01HL-22226-01 Autonomic nervous elements in the
developing heart (rabbits)
ROlHL-22562-02 Mechanism of cardiac action potential
propagation (tunicates)
ROlHL-23726-01 Treatment of ventricular arrhythmias with
propranolol (human)
HEART, CONDUCTION SYSTEM,
ATRIOVENTRICULAR NODE
POlHL-08682-15 0015 Regulation of the cardiovascular
system • Projection of autonomic nerves onto the heart
(dog)
POlHL-08682 15 0016 Regulation of the cardiovascular
system - Shifting cardiac pacemakers and AV nodal
activation (dog)
P01HL08682-I5 0017 Regulation of the cardiovascular
system - Neurally induced cardiac dysrhythmias (dog)
•* R01HL-1095M1 Neural control of the heart (dogs, rats)
POIHLI 1310-12 0074 Mechanisms of cardiovascular
disease Electrophysiological studies of paraxysmal atrial
tachycardia (human)
POlHL-11310-12 0077 Mechanisms of cardiovascular
disease ■ Abnormalities of rhythm and conduction following
heart surgery (human)
"* P01HL11310-12 0079 Mechanisms of cardiovascular
disease - Electrophysiological studies of complete heart
block (human)
** P01HL11310-12 0087 Mechanisms of cardiovascular
disease - Electrophysiology and electropharmacology of the
heart (dogs)
POlHL-1131012 0090 Mechanisms of cardiovascular
disease - Clinicopathologlcal cardiovascular correlation
(human, animals)
ROlHL-12486-10 Structure-function correlation In the
atrium (rabbits)
Physiologic pharmacology and Its
Cardiac electrical activity (human,
POIHL 12738-10 0127
clinical applications
animals)
POlHL-12738-10 0128
clinical applications
Physiologic pharmacology and its
Recording electrograms from
specialized cardiac tissues (human, dogs)
** POlHL-1310809 0017 Clinical heart transplantation ■
Electrophysiology of the transplanted denervated human
heart
POlHL-13108-09 0018 Clinical heart transplantation -
Electrophysiologic studies of cardiac drugs In the
denervated heart
R01HL13920-07 Expanding the role of surgery of atrial
dysrhythmias (dogs)
R01HL19487-03 Cardiac actions of digitalis (dogs, cats)
ROlHL-1976802 Recording and analysis of low levels
cardiac signals (human, dogs)
ROlHL-20328 01 Noninvasive assessment of autonomic
cardiac control (dogs)
** ROlHL-21574-01 Automaticity of AV node and Its adjacent
tissues (dogs)
** ROIHL-22484-01 Neural control of cardiac conduction and
excitation (dogs)
HEART, CONDUCTION SYSTEM, BUNDLE OF HIS
POlHL-l 1310-12 0090 Mechanisms of cardiovascular
disease • Clinicopathologlcal cardiovascular correlation
(human, animals)
Physiologic pharmacology and its
Cardiac electrical activity (human.
POlHL-12738-10 0127
clinical applications
animals)
P01HL12738-10 0128
clinical applications
Physiologic pharmacology and its
Recording electrograms from
specialized cardiac tissues (human, dogs)
ROlHL-13920-07 Expanding the role of surgery of atrial
dysrhythmias (dogs)
P50HL- 1764804 0016 Study of ischemic heart disease -
Intraventricular conduction-Effect of pacing on conduction
and automaticity
ROlHL-18538-03 The role of electrotonus In HisPurkinje
function (dog)
234
** R01HL1976802 Recording and analysis of low levels
cardiac signals (human, dogs)
ROlHL-21574-01 Automaticity of AV node and its adjacent
tissues (dogs)
ROlHL-23599-01 Mechanisms of Ischemic rhythm
disorders (dogs)
HEART, CONDUCTION SYSTEM, HEART
PACEMAKERS
SEE ALSO HEART PACEMAKERS ELECTRONIC
** POlHL-08682-15 0016 Regulation of the cardiovascular
system < Shifting cardiac pacemakers and AV nodal
activation (dog)
PaiHL-08682-15 0017 Regulation of the cardiovascular
system ■ Neurally induced cardiac dysrhythmias (dog)
** R01HL12777-09 Mechanisms in cardiac performance
(dogs, human)
ROIHL 13306-08 Pharmacological control of cardiac
me-.ibrane currents (cattle, rabbits)
** R01HL13920-07 Expanding the role of surgery of atrial
dysrhythmias (dogs)
POlHL-1441407 0016 Environmental Influences on
cardiorespiratory and cellular functions - Effects of
pressure un membrane and cellular function (human,
rabbits)
ROlHL-1574006 In vitro studies on heart cell function
(rats)
ROIHL 1632904 Cardiac surgical effect on heart function
in Infants (human)
** ROlHL-1737003
in Limulus
** ROlHL-1745105
Synaptic chemistry and cardloregulatlon
Digitalis effects on cardiac automaticity
The role of electrotonus in HIs-Purklnje
Experimental cardiac arrhythmias (dogs)
Electrophysiology of cardiac automaticity
mechanisms
** ROIHL 1745204 Depolarization induced cardiac
automaticity (human, animals)
P50HL17648-04 0016 Study of Ischemic heart disease ■
Intraventricular conduction -Effect of pacing on conduction
and automaticity
** ROlHL-1799304 0006 Ventricular dynamics from
surgically Inserted markers - Atrial pacing In transplant
patients
R01HL18053-03 Intracellular Ionic activities in heart
muscle (frogs)
ROlHL-18538-03
function (dog)
ROlHL-18796-04
ROlHL-19045-03
(human, dogs)
** ROlHL-19216-03 Characterization of cardiac pacemaker
activity (cat, dog, rabbit)
ROlHL-20077-02 External cardiac stimulation with
microwave radiation (dogs)
R01HL-2I136-02 Ion activities and transport In cardiac
muscle cells (sheep)
R01HL2152701 Prospective study of bundle branch block
(human)
ROlHL-21742-01 Frequency-dependent drug actions in
cardiac muscle (rabbits)
** ROlHL-22235-01 Mechanism of cardiac pacemaking
(rabbits)
** ROlHL-2227401 Quantltating In series effects In cardiac
arrhythmias (dogs)
** ROlHL-22426-01 Initiation of the heartbeat-A voltage-
clamp study (bullfrogs, rabbits)
HEART, CONDUCTION SYSTEM, PURKINJE
FIBERS
ROlHL-05806-18 Analysis of antiarrhythmic agents (dogs,
rabbits)
** POlHL-06285-18 0212 Cardiovascular-respiratory
physiology and biochemistry ■ Membrane structure and
function -Gap junction (bovine)
ROlHL-08508-15 Cardiac conductivity and automaticity
(human, dogs, rabbits)
P01HL08682-15 0031 Regulation of the cardiovascular
system - Cardiac electrophysiology in hibernation (ground
squirrel, marmot)
R01HL10503-13 Cardiac Ion transport and ultrastructure
(rats, guinea pigs, rabbits)
** ROlHL-12486-10 Structure-function correlation in the
atrium (rabbits)
** P01HL12738-10 0044 Physiologic pharmacology and Its
clinical applications - Cardioactive drugs and
electrophysiological properties of cardiac cells (sheep)
POlHL-12738-10 0081 Physiologic pharmacology and its
clinical applications - Ultrastructural and electrophysiologic
alteration of myocardium (human, dogs)
P01HL12738-10 0108 Physiologic pharmacology and its
clinical applications - Developmental electrophysiology and
pharmacology (human, animals)
P01HL12738-10 0110 Physiologic pharmacology and its
clinical applications - Physiology and pharmacology of
arrhythmias (dogs)
ROlHL-13306 08 Pharmacological control of cardiac
membrane currents (cattle, rabbits)
ROIHL 13666-06 Pharmacology of genesis of cardiac
rhythmicity (rats, cats)
ROlHL-146 14-07 Voltage control of contraction In heart
(sheep)
" POIHL- 151 94-07 0004 Pathophysiology of
cardiopulmonary dysfunction - Specialized electrophysiology
flbers-Electrogenlc basis of glycosides (mammals)
The role of electrotonus In Hls-Purkinje
HEA
ROlHL-17452-04 Depolarization induced cardiac
automaticity (human, animals)
** P50HL-17648-04 0014 Study of ischemic heart disease -
Antidysrhythmic drugs and mammalian cardiac Purklnje
fibers (sheep, dog)
P50HL-17667-04 0031 Study of Ischemic heart disease ■
Pathophysiology In Ischemic heart disease (dog. cat, rabbit,
monkey)
ROlHL-1805303 Intracellular Ionic activities In heart
muscle (frogs)
** R01HL1853803
function (dog)
ROlHL-18795-04 Ischemic arrhythmias-Effect of
autonomic tone (dogs, rats, guinea pigs)
ROlHL-18796-04 Experimental cardiac arrhythmias (dogs)
R01HL-:9044-03 Effect of drugs on development of
cardiac failure (cats)
** ROIHL 19216-03 Characterization of cardiac pacemaker
activity (cat. dog, rabbit)
ROIHL 20153 02 Intracellular pH and myocardial
electropharmacology (dogs, guinea pigs)
** ROIHL 2023002 Analysis of the action potential of
cardiac muscle (sheep)
ROIHL 2027302 Cardiac fiber direction and the QRS
complex (dogs)
ROlHL-20558-02 Cardiac electrophyslology-Effects of Ions
and drugs
" POlHL-20592-02 0004 Cell biology of cardiac and
skeletal muscle ■ Excitation, conduction and contraction-
Modelling in Purklnje fibers
ROlHL-20749'01 Developing heart-Biophysical aspects
(sheep)
** ROlHL-2 1136-02 Ion activities and transport In cardiac
muscle cells (sheep)
R23HL-21 151-02 Ischemic myocardium-Delivery of blood
flow and drugs (dogs)
•* ROlHL-21294-02 Voltage clamp of isolated cardiac
Purklnje cells (dogs)
R23HL 21368-02 Perinatal cardiac electrophysiology (dogs)
ROlHL-21670-01 Antiarrhythmic studies on 2-substltuted
aminoindenes (dogs)
ROIHL 21922-01 Transient currents Induced by
strophanthidin in the heart
ROlHL-23599-01 Mechanisms of Ischemic rhythm
disorders (dogs)
** ROlHL-23624-01 Effect of drugs on ischemic cardiac cells
(dogs, guinea pigs, pigs)
HEART, CONDUCTION SYSTEM, SINO-ATRIAL
NODE
POlHL-0868215 0016 Regulation of the cardiovascular
system - Shifting cardiac pacemakers and AV nodal
activation (dog)
POlHL-l 1310-12 0077 Mechanisms of cardiovascular
disease - Abnormalities of rhythm and conduction following
heart surgery (human)
P01HL11310-12 0079 Mechanisms of cardiovascular
disease - Electrophysiological studies of complete heart
block (human)
*♦ POlHL-11310-12 0087 Mechanisms of cardiovascular
disease - Electrophysiology and electropharmacology of the
heart (dogs)
POlHL-l 1310-12 0090 Mechanisms of cardiovascular
disease - Clinicopathologlcal cardiovascular correlation
(human, animals)
R01HL12486-10 Structure-function correlation in the
atrium (rabbits)
** P01HL12738-10 0035 Physiologic pharmacology and its
clinical applications - Function and dysfunction of the
sinoatrial node (human)
P01HL-I273810 0110 Physiologic pharmacology and its
clinical applications - Physiology and pharmacology of
arrhythmias (dogs)
ROlHL-13920-07 Expanding the role of surgery of atrial
dysrhythmias (dogs)
♦* ROlHL-15190-07 Physiological basis of arrhythmias and
their therapy (human)
ROlHL-15758-06 Catecholamine release in the heart
(dogs)
R01HL16329-04 Cardiac surgical effect on heart function
in Infants (human)
P50HL-1764804 0016 Study of ischemic heart disease -
Intraventricular conduction-Effect of pacing on conduction
and automaticity
P50HL-17651-04 0022 Ischemic heart disease specialized
center of research ■ Electrophysiology-Mechanism and
pharmacology of arrhythmias (human, dog)
P50HL-17667-04 0018 Study of ischemic heart disease ■
Arrhythmias In ischemic heart disease (human)
P50HL-17667-04 0031 Study of Ischemic heart disease -
Pathophysiology in Ischemic heart disease (dog. cat. rabbit,
monkey)
Prospective studies of conduction disease
Morphometric analysis of the sinoatrial
Vagal control of heart rate-A biophysical
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subiecl.
■ROlHL-18794-04
(human)
R01HL19009-03
node (ferret)
R01HL19076-03
model (rabbits)
R01HL19216-03 Characterization of cardiac pacemaker
activity (cat, dog, rabbit)
ROlHL-20077-02 External cardiac stimulation with
microwave radiation (dogs)
(contd)
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
HEA
ROIHL 20328 01 Nonicivusivo assessment of autonomic
cardiac control (da(s)
ROtHl 2U4b 0? Response of atria to liyparosmolality
Mectianisms Irabbils)
R23HL 21368 02 Perinatal cardiac electropliysiology (dots)
** ROIHL 2223S01 Meclianism of cardiac pacemakini
(rabbits)
ROIHL 22426 01 Initiation of the heartbeat A voltage'
clamp study (bullfrogs, rabbits)
" ROIHL 22484 01 Neural control ol cardiac conduction and
excitation (dogs)
ROIHL 22546 02 Baioreceptor reflen mechanisms in man
HEART, ENDOCARDIUM
•• P01HL0628S 18 0143 Cardiovascular respiratory
physiology and biochemistry Myocardial ischemia (human.
dogs, lambs)
POIHI 10539 12 0068 Pathophysiology of circulation
Acute and chronic cardiomyopathies (mice. dogs, hamsters.
human)
POIHL 12738 10 0092 Physiologic pharmacology and its
clinical applications Subendocardial ischemia following
op«n heart surgery (human)
** POIHL 13108 09 0003 Clinical heart transplantation -
Endomyocardial biopsy pathology
P60HL1 7269-04 0026 National heart and blood vessel
research and demonstration center Dynamics of ischemic
heart disease (human, dog)
P50HL-1766S 04 0021 Study of ischemic heart disease
Identification, prevention -Myocardial ischemia in
cardiopulmonary bypass (dog)
ROlHL-18468 03 The distribution of flow in the
myocardium (dog, pig)
ROlHL-19072-03 Modification of tissue injury in
myocardial infarction (dogs, human)
ROlHL-1914803 Myocardial organelle lipid structure and
function (dog. rat)
ROlHL-19995-02 Sensory transduction in cardiac
mechanoreceptors (cats, frogs, rats)
R23HL-21253-01 Anatomical models in computer-aided
image analysis
HEART, FORAMEN OVALE EMBRYONIC
POlHL-06285-18 0126 Cardiovascular-respiratory
physiology and biochemistry - Ventricular output, foramen
ovale and ductus arteriosus flows (lambs)
HEART, MYOCARDIUM
ROlHL-01813-25 Regulation of metabolism by drugs and
hormones (rats)
R01HL-029S317 Autonomic and cardiovascular
pharmacology (rats, rabbits, dogs, guinea pigs)
** POlHL-03174-23 0007 Mechanisms of acute vascular
reaction to injury - Healing of injured myocardium-Basal
lamina scaffold (human, rats, dogs)
ROlHL-05806-18 Analysis of antiarrhythmic agents (dogs,
rabbits)
ROlHL-05883-18 0008 Reflex control of resistance and
capacitance vessels - Oxygen consumption of the
chronically denervated dog heart
•* ROlHL-05949-18 Biochemistry of muscle contraction (rats,
rabbits)
POlHL-05285-18 0131 Cardiovascular-respiratory
physiology and biochemistry - Fetal heart development and
ventricular outflow obstruction (lambs)
** POlHL-06285-18 0156 Cardiovascular-respiratory
physiology and biochemistry - Myocardial performance
following revascularization (human)
*• POlHL-06285-18 0173 Cardiovascular-respiratory
physiology and biochemistry - Skeletal and cardiac muscle
function
POlHL-06285-18 0179 Cardiovascular-respiratory
physiology and biochemistry - Regulation of myocardial cell
growth (rats, chick embryo)
POlHL-06296-18 0007 Cardiovascular and pulmonary
adaptation to stress - Cardiovascular control during
isometric exercise (cats)
** POlHL-06308-18 0042 Mechanisms and therapy of
circulatory disease - Echocardiographic assessment of
arrhythmias -Myocardial tissue type (human, dogs)
" POlHL-06312-17 0033 Surgical cardiology - Studies in
cryopreservations (rats)
** POlHL-06312-17 0034 Surgical cardiology - Metabolic
factors in cardiac function-Creatine phosphate depletion
(animals)
** POlHL-06312-17 0044 Surgical cardiology - The limits of
topical cardiac hypotliermia with ice chips (rats)
** POlHL-06312-17 0047 Surgical cardiology - Myocardial
extravascular water (dogs)
** POlHL-06312 17 0051 Surgical cardiology - Diuretic
therapy on myocardial electrolyte composition and water
content (human)
** ROlHL-06924-16 Humoral and metabolic aspects of
cardiac function (mammals, non-human, human)
ROlHL-08311-14 Effects of drugs upon myocardial hypoxia
(dogs, turtles)
POlHL-08682-15 0006 Regulation of the cardiovascular
system - Cardiovascular studies of mammalian hibernators
(sciuromorpha)
POlHL-08682-15 0031 Regulation of the cardiovascular
system - Cardiac electrophysiology in hibernation (ground
squirrel, marmot)
335
POIHI 08682 15 0036 Regulation of the cardiovascular
system [lectrolyte transport in myocardium with
hemoirhagic shock (rats)
POIHL 08805 15 0050 Regulation ol ventilation and
pulmonary circulation Right ventricular mechanics (dogs)
ROIHL 091/2 15
muscle (rats)
Protein and RNA synthesis in heart
Pharmacology of molluscan hearts (also
Myocardial lipid metabolism and
ROIHL 09283 14
rabbits)
ROIHL 09489 13
regulation (rats)
ROIHL 10503 13 Cardiac ion transport and ultrastructuie
(rats, guinea pigs, rabbits)
POIHL 10539 12 0067 Pathophysiology of circulation
Mechanical, electrophysiological studies- Isolated heart
muscle (dog. rat)
POIHL 10539 12 0070 Pathophysiology of circulation
Effects of hypertension on myocardial blood flow after
coronary occlusion (dogs)
POIHL 11310-12 0062 Mechanisms of cardiovascular
disease Myocardial depressant factor in postoperative
cardiac dysfunction (human, dogs)
P01HL-U3 10-12 0085 Mechanisms of cardiovascular
disease - Mechanics ol isolated cardiac muscle (animals)
POlHL-11310 12 0086 Mechanisms of cardiovascular
disease Mechanics of the intact left ventricle (dogs)
POIHL 11310-12 0089 Mechanisms of cardiovascular
disease - Structure and function in myocardial contraction
(dogs)
POIHL 11351-12 Cellular and molecular mechanisms of
myocardial function
POlHL-11351 12 0003 Cellular and molecular
mechanisms of myocardial function Mechanical and
electrical properties of cardiac muscle (rabbits)
' POlHL-11351 12 0009 Cellular and molecular
mechanisms of myocardial function Myocardial membrane
surface coat (rats, rabbits)
' ROlHL-11551 11 RNA and protein synthesis in repair of
heart injury (mice, rats)
Functions and mechanisms of cell
- Developing structure of heart
POIHL 12157 11 0037
membrane ion transport
cells in tissue culture
POlHL-121 57-11 0052
membrane ion transport
synthetic strand
P01HL12157-11 0054
membrane ion transport
Functions and mechanisms of cell
- Active electrical properties of the
Functions and mechanisms of cell
- Simulation of electrogenic ion
transport in cardiac muscle
POlHL-12157-11 0056 Functions and mechanisms of cell
membrane ion transport - Isotopic fluxes in synthetic
strands of heart cells (chick embryo)
POlHL-12157-11 0057 Functions and mechanisms of cell
membrane ion transport - Electrophysiological
investigations of synthetic strands of heart muscles (rats)
R01HL-12186-09 Calcium transients in striated muscle
and other cells (mammals, frogs)
POlHL-12373-10 0002 Cardiopulmonary physiology and
pathophysiology - Determinants of performance of the
whole heart (dogs)
POIHL 12373-10 0005 Cardiopulmonary physiology and
pathophysiology - Characterization of fetal and neonatal
myocardium (human, cats)
POlHL-12373-10 0012 Cardiopulmonary physiology and
pathophysiology - Biochemistry of the sympathetic nervous
system (rats, rabbits, pigeons)
ROlHL-127 11-09 Mathematical approach to cardiovascular
mechanics (human, animals)
POlHL-12738-10 0069 Physiologic pharmacology and its
clinical applications - Blood rheology in coronary heart
disease (dogs)
POlHL-12738-10 0081 Physiologic pharmacology and its
clinical applications - Ultrastructural and electrophysiologic
alteration of myocardium (human, dogs)
POlHL-12738-10 0135 Physiologic pharmacology and its
clinical applications - Myocardial cells in tissue culture
(rats, chick embryo)
ROlHL-12777-09 Mechanisms in cardiac performance
(dogs, human)
ROlHL-13028-09 Regulation of myocardial fatty acid
metabolism (rats)
ROlHL-13029-09 Metabolic regulation of sugar transport
(pigeons, rats)
ROlHL-13306-08 Pharmacological control of cardiac
membrane currents (cattle, rabbits)
ROlHL-13339-08 Pharmacology of developing cardiac
tissues (chick embryo)
ROlHL-13349-06 Analysis of activation process in heart
muscle (guinea pigs, rabbits, human)
ROlHL-13630-08 Control of glycogen synthesis in heart
(cattle)
ROlHL-1371508 Myocardial adenyl cyclase (rats)
POlHL-13737-07 0024 Assisted circulation - Dynamic
prosthetic myocardium (do.s)
ROlHL-13831-08 Factors regulating embryonic cardiac
morphogenesis (chick, salamandra)
POlHL-13851-16 Cyclotron produced isotopes in biology
and medicine (human. anima'S)
ROlHL-13870-09 Control of myocardial sarcotubular
calcium stores (dogs)
ROlHL-14148-07 0009 The regional circulations -
Myocardial circulation in hypertension and atherosclerosis
(human)
HIA
P50HL 14736 05 0002 Pmvtntion ol piemtturi
■ rterioscleroiii Myocaidiil blood tlow in patienti with
coronary arthiiroicleiotis
" POIHI 14388 0/ 0161 Regulation of the circulation in
pathological statat Heterogeneity of l*(t vanlncular
perfusion in awake dogs
•* POIHL 143880/ 0162 Regulation of the circulation in
pathological stales Phasic coronary (low and myocardial
perfusion in aortic regurgitation (dogs)
•• POIHL 14388 07 0168 Regulation of the circulation in
pathological states Ionic basis of depolarization (rait,
tissue culture)
•• POIHL 14388 0/ 01/2 Regulation of the circulation in
pathological states cAMP dependent protein kinase from
heart and vascular smooth muscle (guinea pigs)
•" POIHL 14388-07 01/5 Regulation of the circulation in
pathological states Functional studies of selected proteins
from cardiac muscle
•* POIHL 14388 0/ 0221 Regulation of the circulation in
pathological states Experimental myocardial infarction
(dogs)
** POIHL 144140/ 0010 Environmental influences on
cardiorespiratory and cellular functions Pressure effects
on cardiac electrical phenomena (animals)
POIHL 14414 07 0014 Environmental influences on
cardiorespiratory and cellular functions Temperature and
acid base status in tissues, cells, and subcellular system
POIHL 144140/ 0016 Environmental influences on
cardiorespiratory and cellular functions Effects of
pressure on membrane and cellular function (human,
rabbits)
** ROIHL 14730-07 Fatty acid beta oxidation in normal and
ischemic hearts (rabbits)
•* ROIHL 14938-06 Contractile proteins of heart muscle
(dogs, rabbits)
ROIHL 15391-07 EPR studies on rotational motion of
myosin and actin
ROlHL-1567906 Heart and smooth muscle contcaclile
protein (swine, cattle, rabbits, chickens)
** ROlHL-15692 07 Force and speed in skeletal and cardiac
muscle
ROIHL 15799-04 Effect of anesthetics on myocardial
function (cats)
** POlHL-15835-06 0002 Study of muscles related to heart
disease Proteins of smooth muscle system (cattle,
rabbits)
POlHL-15835-06 0006 Study of muscles related to heart
disease - Ultrastructural and chemical studies of muscle
(animals)
** POIHL- 15835 06 0007 Study of muscles related to heart
disease Structure and function of Limulus striated and
cardiac muscle
** POIHL 15835-06 0009 Study of muscles related to heart
disease - Aspects of cardiac and skeletal myogenesis
(chick embryo)
POlHL-15835-06 0010 Study of muscles related to heart
disease - Muscle structure and reaction to injury (mice,
rats)
POlHL-1583506 0011 Study of muscles related to heart
disease - Energetics and mechanism of muscle contraction
(frogs, rabbits)
POlHL-15835-06 0013 Study of muscles related to heart
disease - Cardiac bioenergetics (rats)
POlHL-15835-06 0019 Study of muscles related to heart
disease - Vascular smooth muscle-Electron microscopy,
excitation contraction (animal)
POIHL- 15835-06 0021 Study of muscles related to heart
disease - Fast kinetic studies in muscle subcellular
organelles (animals)
** POlHL-15835-06 0023 Study of muscles related to heart
disease - Cellular basis of the Frank-Starling curve (frogs,
rats)
POlHL-15835-06 0025 Study of muscles related to heart
disease - Cellular biology of vascular smooth muscle
(guinea pig)
** ROlHL-15888-05 Comparative stereology of the
myocardium (birds, mammals)
** ROlHL-15985-06 Metabolic and hormonal control of
cardiac contraction
Evaluation of heart stimulants in sea
Cellular basis of cardiac contractility
ROlHL-15991-05
anemones
ROlHL-16010-16
(frogs)
ROlHL-16037-06 Molecular properties of cardiac
adrenergic receptors
ROlHL-16219-05 Mechanisms of atherogenesis in chronic
uremia (human, rats)
POlHL-16251-06 0002 Membrane-bound enzymes in heart
and other tissues - Structural basis of regulation of
cardiac succinate dehydrogenase
ROlHl-16420-02 Effect of training-detraining on the rat
heart
ROlHL-16507-04 Heart cell interactions and cell lunction
biogenesis (mice, rats, rabbits)
ROlHL-16637-04 Development and regression of cardiac
hypertrophy (rats)
ROlHL-16678-03 Fluorescent probe studies of heart
muscle proteins (rabbit, dog)
POlHL-16683-04 Function and growth of cardiac and
skeletal muscle
(OMtd)
'Excludes routine methodokigy OR covers only general projects which preclude Indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
HEA
236
HEA
POlHL-16683-04 0001 Function and growth of cardiac
and siteletal muscle - Light chains of the skeletal and
cardiac myosin molecule (rabbits, frogs)
P01HL16683-04 0003
and skeletal muscle
fibers
P01HL16683-04 0006
and skeletal muscle
Function and growth of cardiac
Movements of SI moieties in muscle
Studies of myocardial reactive hyperemia
Function and growth of cardiac
Chemical studies of the contractile
system-Development of new reagents
R01HL'ie710-03 Myocardial subcellular localization of
calcium (dogs)
P60HL-172e9-04 0019 National heart and blood vessel
research and demonstration center - Sarcoplasmic
reticulum (dog, rabbit, hamster, cat)
PeOHL'l 7269-04 0020 National heart and blood vessel
research and demonstration center - Nucleic acid and
protein metabolism in growth and development of heart
(rat)
R01HL-1737e-04 Analysis of Z bands in heart by optical
diffraction (mammals)
R01f(L-17452-04 Depolarization induced cardiac
automaticity (human, animals)
P50HL-17646-04 0004 Study of ischemic heart disease -
Core experimental animal laboratories
P50HL' 17648-04 0004 Study of ischemic heart disease -
Radionuclide imaging studies (human, pig)
P50HL-17648-04 0025 Study of ischemic heart disease -
Destruction and repair of cardiac muscle cell constituents
(rat)
P50HL-17651-04 0016 Ischemic heart disease specialized
center of research - Retroperfusion of coronary venus
circulation with therapeutic agents (dogs)
P50HL17655-04 0010 Study of ischemic heart disease -
Core facility-Cardiovascular pathology (human, animal)
P50HL17665-04 0029 Study of ischemic heart disease -
Myocardial protein synthesis and degradation in low oxygen
states (rabbit, dog)
P50HL-17669-04 0006 Ischemic heart disease center
(SCOR) - Studies of hypoxic, acidotic and ischemic cardiac
muscle (dogs)
P50HL-1767004 0022 Study of ischemic heart disease -
Myocardial metabolism in hypoxia and recover (rabbit.
toad, dog)
ROlHL-1770204 Electro-optical dyes as probes of heart
excitability
ROlHL-1775903
(dogs, human)
R01HL-17799-02 The presence and significance of heart
acetylcholine (cats)
ROlHL-17809-04 Effects of exercise on the coronary
vasculature (rat, dog)
ROlHL-17859-04 Computational methods in cardiac fluid
dynamics
ROlHL-1797618 Chemical agents and heart glycolytic
enzymes (sheep)
ROlHL-1799304 0006 Ventricular dynamics from
surgically inserted markers - Atrial pacing in transplant
patients
ROlHL-18053-03 Intracellular ionic activities in heart
muscle (frogs)
R01HL-I808904 Fatty acid metabolism in heart and its
regulation (swine, rats)
ROlHL-18176-02 Effect of thyroid hormone on cultured
cardiac cells (rats)
ROlHL-18179-03 Heart, platelet, and muscle myosins and
actomyosins (cattle)
ROlHL-18304-03 FT-infrared spectroscopy of heart muscle
energetics (cattle)
ROIHL- 18468-03 The distribution of flow in the
myocardium (dog, pig)
ROlHL-18538-03
function (dog)
ROlHL-18598-03
digitalis action
ROlHL-18629-04 Influence of aging and hypertension on
the myocardium (rats)
R01Ht.-1863103 Ultrastructural correlates of myocardial
ischemia (rats, swine)
ROlHL-18676-03 Myocardial sarcomere mechanics (rat)
ROlHL-18795-04 Ischemic arrhythmias -Effect of
autonomic tone (dogs, rats, guinea pigs)
ROlHL-18796-04 Experimental cardiac arrhythmias (dogs)
ROlHL-18798-04 0002 Nervous and ionic factors in
sudden cardiac death • Electron microprobe, ultrastructure
analysis of ischemic myocardium (dog, rabbit)
ROlHL-18824-03 Mechanisms of heart failure in
myopathic hamster
ROIHL 19000-03 Irreversible myocardial injury (rats)
ROlHL-19008-02 Carbon dioxide diffusion in lung and
muscle tissues (dogs)
ROlHL-19044-03 Effect of drugs on development of
cardiac failure (cats)
ROlHL-19072-03 Modification of tissue injury in
myocardial infarction (dogs, human)
R01HL19139-03 Dispersion of diffusible indicators in the
body (human, cats, dogs)
ROlHL-19148-03 Myocardial organelle lipid structure and
function (dog, rat)
R01HL19182-03 Surgical aspects of myocardial
hypertrophy (dogs)
ROlHL-19299-03 Myoglobin and oxygen supply to heart
and muscle cells (rats, pigeons)
The role of electrotonus in His-Purkinje
Role of Na, K-ATPase inhibition on
Regulation of myocardial acylcarnitine
Regulation of protein turnover in diabetic
ROlHL-19366-03 Renal Starling forces in experimental
conditions (rats, rabbits)
ROIHL' 194 14-03 Protection of myocardium during cardiac
surgery (dogs, cats, human)
ROlHL-19648-03 Myocardial protein degradation (dogs,
rabbits)
R01HL-19653-03 Circulatory system effects of angiotensin
analogs (rats)
POlHL-19737-02 0009 Cellular and molecular aspects of
respiratory physiology - Regulation of tissue oxygen tension
and body carbon monoxide stores (human, dogs)
ROlHL-20132-03 Histogenesis and biochemistry of
embryonic lung (birds)
ROlHL-20153-02 Intracellular pH and myocardial
electropharmacology (dogs, guinea pigs)
ROlHL-20230-02 Analysis of the action potential of
cardiac muscle (sheep)
ROlHL-20253-02 Effects of exercise on the heart and its
blood supply (dogs)
ROlHL-20273-02 Cardiac fiber direction and the QRS
complex (dogs)
ROlHL-20308-02
transport (rats)
ROlHL-20388-03
heart (rat)
ROlHL-20464-01 Regulation of cardiac and skeletal
muscle contraction (mammals)
ROlHL-20544-02 Integrated regulation of myocardial
energy metabolism (rats, guinea pigs)
POlHL-20552-02 0001 The development and regression of
cardiac hypertrophy - Biochemical events in cardiac
hypertrophy (rats)
ROIHL-20558-02 Cardiac electrophysiology-Effects of ions
and drugs
POlHL-2059202 0001 Cell biology of cardiac and
skeletal muscle - Molecular mechanism of muscle
contraction (animals)
POIHL 20592-02 0011 Cell biology of cardiac and
skeletal muscle - Myosin and cytochrome oxidase
messenger RNAs (chicken)
POlHL-20592-02 0012 Cell biology of cardiac and
skeletal muscle - Contractile properties of skinned muscle
fibers (frogs)
■ ROlHL-2061302
myocardium
' ROlHL-20658-01 Myocardial energy transport -Creative
kinase (human, cattle, dog)
ROlHL-20720-02 Myocardial protection during
cardiopulmonary bypass (dogs)
' ROlHL-20749-01
(sheep)
ROlHL-20754-02
(rabbits)
ROlHL-20787-02 Thromboxanes and prostaglandins-
Biochemical pharmacology (rabbits, human)
ROlHL-20793-02 Phospholipids and cardiac receptor
function
ROlHL-20895-03 0002 Cineangiographic studies of
cardiovascular system - Coronary disease-Regional
myocardial blood flow (human, dog)
POlHL-20984-02 0003 Cellular mechanisms in cardiac
hypertrophy - Fast-kinetics of myosin ATPase from normal
and hypertrophied heart (rabbits)
R23HL-210S1-02 Adrenergic receptors and the adenylate
cyclase system (frog RBC)
ROlHL-21136-02 Ion activities and transport in cardiac
muscle cells (sheep)
' R23HL'21 151-02 Ischemic myocardium-Delivery of blood
flow and drugs (dogs)
ROlHL-21 172-02 Regional oxygen consumption of heart
and other organs (animals)
ROlHL-21195-02 Innervation of the heart-Acetylcholine
receptors (frogs)
R23HL-21 196-02 Digitalis induced arrhythmia and NAO KO-
atpase activity (dogs)
' R23HL-21262-02 Sodium-calcium interactions in
mammalian myocardium (rabbits, cats)
' ROlHL-213 12-01 Sarcomere mechanics in disrupted
ventricular muscle (guinea pigs)
R23HL-21327-02 Molecular mechanisms of chemical
myocardiopathies (rats)
ROlHL-21329-02 Beta-receptor regulation and cardiac
sites of drug action (cat, guinea pig, rat)
' ROlHL-21371-02 Energy loss microanalysis of myocardial
cations
' ROlHL-2 1381-02 Amino acid metabolism in normal and
hypoxic myocardium (rabbits)
ROlHL-21471-02 Structure-function studies on actin and
myosin (human, protozoa, rabbits, cattle)
* ROlHL-21742-01 Frequency-dependent drug actions in
cardiac muscle (rabbits)
ROlHL-21786-01 Long-term effects of myocardial
protection (dogs, rats)
' ROlHL-21922-01 Transient currents induced by
strophanthidin in the heart
* ROlHL-21970-01 Myofibrillar assembly and breakdown In
cardiac muscle (rats)
Cardiac energy metabolism and protein
Mechanical properties of isolated
Developing heart-Biophysical aspects
Anesthetic-induced myocardial depression
ROlHL-22039-02
rodents, cattle)
ROlHL-22136-02
ROlHL-221 52-02
surgery (dogs)
Ion transport in cardiac muscle (dogs.
Histamine and cardiac adenyl cyclase
Ventricular dysfunction and cardiac
Neurotransmitter receptors of cultured
Cardioselectivity of beta-adrenoceptor
Myosin as a multi-enzyme complex (dogs.
R01HL-22226-01 Autonomic nervous elements in the
developing heart (rabbits)
ROlHL-22231-02 Modulation of calcium control of cardiac
myofibrils (rats)
ROlHL-22290-01
synthesis (mice)
ROlHL-22315-01 Intraoperative cardiac oxygen supply-
demand (dogs, rabbits, rats)
ROlHL-22329-01 Active prosthetic myocardium -Effects on
LV function (dogs)
ROlHL-22401-01 Regulation of tension and active state in
the heart
ROlHL-22461-01 Cardiac tropomyosin and tropomyosin-
action interactions (rabbit)
R23HL-22490-01
heart cells
ROIHL 22522-01
antagonists
ROlHL-22538-01
rabbits)
ROlHL-22568-01 pH effect in heart cells-Influence of
cardiac drugs (tissue culture, rats)
POlHL-22619-01 0007 Cellular mechanisms of heart
failure Regulation of contractile protein levels in heart
muscle (rats)
POlHL-226 19-01 0009 Cellular mechanisms of heart
failure - Sarcoplasmic reticulum in cardiac, skeletal and
smooth muscle (rabbits, dogs)
ROlHL-22651-01 Control of protein metabolism in heart
muscle
ROlHL-22664-01 Regulation of myocardial cell growth
(rats, guinea pigs)
ROlHL-22685-01 Drugs and excitation-contraction coupling
in heart (animals)
ROlHL-22759-01 Regional myocardial blood flow during
hypothermia (dogs)
ROIHL 22767-01 Model system for cardiac action
potentials (squid, axons)
ROlHL-22859-01 Effect of carbon monoxide on the
developing heart (rats)
ROlHL-22873-01 Adrenoceptor interconversion and
hormone homeostasis
ROlHL'22894-01 Two dimensional ultrasound and cardiac
surgery (human, dogs)
ROlHL-22917-01 Microvascular pressures in the intact
beating heart (rabbits)
R13HL-23072-01 Gordon Research Conference-Cardiac and
skeletal muscle (New Hampshire)
ROlHL-23183-01
membranes
ROlHL-23587-01
(guinea pigs)
ROlHL-23603-01
disease (rats)
Voltage dependent conductance in
Phosphorylation of myocardial protein
Morphogenesis of hypertensive vascular
*Exctude$ routine methodotogy OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
HEART, MYOCARDIUM INTERCALATED DISCS
R01HL-I4713-06 Hypothermia and the heart (bats, guinea
pigs)
ROlHL-14717-06 Hemodynamics and heart structure-
Ventricular overload (dogs)
** P01HL161 17-05 0001 Ion movements and membranes in
cardiovascular control - Developmental studies of
contractile cell junctions (rats, rabbits, elasmobrancti)
P50HL-1 766904 0002 Ischemic heart disease center
(SCOR) - Myocardial Infarction sizing by radioimmunoassay
of cardiac myosin (dogs)
ROlHL-18629-04 Influence of aging and hypertension on
the myocardium (rats)
ROlHL-1863103 Ultrastructural correlates of myocardial
ischemia (rats, swine)
** POlHL-20592-02 0006 Cell biology of cardiac and
skeletal muscle - Permeability and ultrastructure of cardiac
nexuses (rabbits, cattle, rats)
POlHL-20984-02 0004 Cellular mechanisms in cardiac
hypertrophy ■ Myofibril accumulation in cardiac and
vascular muscle cells in hypertrophy
HEART, PAPILLARY MUSCLES
POlHL-06285-18 0153 Cardiovascular-respiratory
physiology and biochemistry - Myocardial mechanics and
pharmacology in isolated papillary muscle (animals)
POlHL-08682-15 0031 Regulation of the cardiovascular
system - Cardiac electrophysiology in hibernation (ground
squirrel, marmot)
ROlHL-12486-10 Structure-function correlation in the
atrium (rabbits)
POlHL-12738-10 0109 Physiologic pharmacology and its
clinical applications - Effects of calcium blockers on
skeletal and cardiac muscle (cats)
ROlHL-13666-06 Pharmacology of genesis of cardiac
rhythm icity (rats, cats)
ROlHL-15522-06 Influence of mannitol on ischemia
cardiac muscle (dogs, cats, rats)
P60HL-17269-04 0021 National heart and blood vessel
research and demonstration center - Growth and
development of heart-Ultrastructure (dog, guinea pig, rat,
cat)
P50HL-17646-04 0004 Study of ischemic heart disease -
Core experimental animal laboratories
P50 ML- 17665-04 0021 Study of ischemic heart disease -
Identification, prevention-Myocardial ischemia in
cardiopulmonary bypass (dog)
(contd)
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
P50HL 17665 04 0029 Study ol ischemic heait disenso
Myocaidial protdn synthesis and detiadstion in low onygen
states (labblt. do|)
PbOHL 1766904 0007 Ischemic heart disease center
(SCOR) Relationship between myocardial depression and
compliance (dogs, cats)
PMHl 17669 04 00?2 Ischemic heart disease center
(SCOR) Pathological studies ot human and experimental
ischemic heart disease
PbOHL 17670 04 0022 Study ol ischemic heart disease
Myocardial metabolism in hypoxia and recover (rabbit,
toad, dog)
P50H1 17670 04 0023 Study ot ischemic heart disease
Energy metabolism in acute myocardial ischemic injury
(dogs)
ROim 19133 03 Contractile and elastic properties ot
cardiac muscle (cats)
ROIHL'19423'03 Catecholamine action on the heart (cats.
rats)
ROIHL 19460 03 Mechanics ot the papillary muscle and
the left ventricle (cats, rabbits)
ROIHL 2015302 Intracellular pH and myocardial
electropharmacology (dogs, guinea pigs)
ROIHL 20184 02 Desensitization ot tracheal muscle to
isoproterenol (rats, rabbits)
ROIHL 20426 03 Myocardial lunction in diabetes mellitus
(dog. rat)
POIHL 20592 02 0003 Cell biology of cardiac and
skeletal muscle Cellular magnesium and anion activities
in ion-specific microelectrodes (frogs)
ROIHL 2061302 Mechanical properties of isolated
The regulation of cardiac hypertrophy
myocardium
R23HL-21234-02
(rabbits)
ROlHL-2138102 Ammo acid metabolism in normal and
hypoxic myocardium (rabbits)
ROlHL-21570-01 The mechanical basis of myocardial
energetics (cats)
ROlHL-2210102 Hormone-substrate interaction in diabetic
myocyte (dogs, rats)
ROlHL-22269-01 Excitation-contraction coupling in
enlarged hearts (rabbits)
ROlHL-23138-01 Myocardial ischemia (dogs. rats, chick
embryo)
ROlHL-23161-01 0004 Biology of myocardial ischemia -
Structure of myofibrils and membranes in early ischemia
(dogs, rabbit, rodents)
HEART, SEPTUM
POlHL-1 1351-12 0013 Cellular and molecular
mechanisms of myocardial function ■ Ion exchange in the
perfused septum high-resolution technique (rabbits, rats)
HEART, VALVES
SEE ALSO HEART DISORDERS. VALVULAR
ROlHL-14785-07 Ultrasonic scattering for tissue
characterization (dogs, cattle, human)
** ROlHL-18593-03 Characterization of heart valve collagen
(human, pig)
ROlHL-187 14-04 Cardiovascular matrix -Morphogenesis
and maturation (human, chick embryo, mammal)
ROlHL-21985-01 Videoroentgenography in congenital heart
disease
HEART, VALVES, AORTIC VALVE
POlHL-12738-10 0094 Physiologic pharmacology and its
clinical applications - Ventricular function and structure
(human, dogs)
** ROlHL-16935-05 Tissue organization and turnover in the
semilunar valve (dogs, rats)
P50HL-17665-04 0020 Study of ischemic heart disease -
Ischemic injury to myocardium during measured states of
ischemia (human)
** ROlHL-1 7969-04 Function and structure of semilunar
valves (dogs)
** ROlHL-20829-02 Fluid mechanics of heart valve
prostheses (dogs, human)
HEART, VALVES, MITRAL VALVE
ROlHL-08508-15 Cardiac conductivity and automaticity
(human, dogs, rabbits)
POlHL-12373-10 0003 Cardiopulmonary physiology and
pathophysiology - Myocardial function in man
** POlHL-1273810 0080 Physiologic pharmacology and its
clinical applications - Electrophysiology of cardiac muscle
in the mitral valve (monkeys)
** POlHL-12738-10 0127 Physiologic pharmacology and its
clinical applications - Cardiac electrical activity (human,
animals)
ROlHL-12777-09 Mechanisms in cardiac performance
(dogs, human)
P50HL-17651-04 0032 Ischemic heart disease specialized
center of research - Cardiovascular surgery core (human,
dogs)
HEART, VALVES, PULMONARY VALVE
ROlHL-17969-04 Function and structure of semilunar
valves (dogs)
HEART, VALVES, TRICUSPID VALVE
P01HL-13330-08 0031 Mechanical circulatory support -
Hemodynamics of cardiac prosthesis
ROlHL-13803-07 Advanced cardiac valvular and vascular
prosthesis (dogs, baboons)
237
HEART, VENTRICLES
ROIHL 05883 18 0004 Rcllox control ol resistance and
capacitance vessels Lett ventricular receptors with
nonmedullaled vagal allerents (cats)
POIHL 06285 18 0126 Cardiovascular respiratory
physiology and biochemistry Ventricular output, foramen
ovale and ductus arteriosus Hows (lambs)
POIHL 06285 18 0155 Cardiovascular respiratory
physiology and biochemistry Therapeutic alterations.
contractile state in heart failure
P01HL06285 18 0156 Cardiovascular respiratory
physiology and biochemistry Myocardial performance
following revascularization (human)
** POIHL 06285 18 0157 Cardiovascular respiratory
physiology and biochemistry Left ventricle outflow
impedance analysis (human)
" P01HL06285 18 0158 Cardiovascular respiratory
physiology and biochemistry Load on myocardial
contractility (dogs)
P01HL06285 18 0179 Cardiovascular respiratory
physiology and biochemistry Regulation of myocardial cell
growth (rats, chick embryo)
•* POlHL-06312 17 0030
artificial heart (calves)
Surgical cardiology Total
Surgical cardiology Left ventricle
POIHL 063 12 17 0040
assist (dogs)
POIHL 063 12 17 0041 Surgical cardiology A
servomechanism for left ventricular assist (human, dogs,
sheep)
P01HL06312 17 0042 Surgical cardiology ■ Right
ventricular assist device (sheep)
POlHL-06312 17 0043 Surgical cardiology - The
cylindrical ventricular assist device (dogs)
POlHL-06312-17 0044 Surgical cardiology The limits ol
topical cardiac hypothermia with ice chips (rats)
POlHL-08805-15 0050 Regulation of ventilation and
pulmonary circulation - Right ventricular mechanics (dogs)
POIHL 10436-13 0006 A multidisciplinary study of
congenital heart disease Ventricular blood pumps and
valves (human, cattle)
POlHL-10539-12 0067 Pathophysiology of circulation -
Mechanical, electrophysiological studies -Isolated heart
muscle (dog. rat)
' POlHL-10539-12 0069 Pathophysiology of circulation -
Ventricular compliance and mechanics in intact ventricles
(human)
POlHL-1131012 0089 Mechanisms of cardiovascular
disease ■ Structure and function in myocardial contraction
(dogs)
POlHL-12373-IO 0005 Cardiopulmonary physiology and
pathophysiology Characterization of fetal and neonatal
myocardium (human, cats)
ROlHL-127 11-09 Mathematical approach to cardiovascular
mechanics (human, animals)
POlHL-12738-10 0094 Physiologic pharmacology and its
clinical applications - Ventricular function and structure
(human, dogs)
ROlHL-12774-08 Ionic coupling in activation of cardiac
muscle (frogs, guinea pigs)
R01HL12777-09 Mechanisms in cardiac performance
(dogs, human)
ROlHL-1342609 Left ventricular bypass for myocardial
infarction (cattle, human)
* POlHL-14388-07 0161 Regulation of the circulation in
pathological states - Heterogeneity of left ventricular
perfusion in awake dogs
* POlHL-14388-07 0213 Regulation of the circulation in
pathological states - Regulation of the heart and peripheral
circulation in heart failure
* P01HL14388-07 0214 Regulation of the circulation in
pathological states - Deformation pattern and stress
analysis of the left ventricle
* POlHL-14388-07 0215 Regulation of the circulation in
pathological states - Left ventricle model in
pathophysiologic states
POlHL-14388-07 0218 Regulation of the circulation in
pathological states - Regional myocardial dyskinesis-Cause
assessment and reduction (dogs)
* ROlHL-14651-05
(dogs, rats)
Mechanical behavior of left ventricle
Contractile proteins of heart muscle
ROlHL-14938-06
(dogs, rabbits)
ROlHL-16329-04 Cardiac surgical effect on heart function
in infants (human)
ROlHL-16484-04 Radiographic ventriculometry for coronary
heart disease (human)
P60HL- 172 69-04 0021 National heart and blood vessel
research and demonstration center - Growth and
development of heart-Ultrastructure (dog, guinea pig, rat,
cat)
P60HL-17269-04 0026 National heart and blood vessel
research and demonstration center - Dynamics of ischemic
heart disease (human, dog)
P60HL- 172 69-04 0032 National heart and blood vessel
research and demonstration center - Clinical circulatory
assist device fabrication
P50HL-17646-04 0002 Study of ischemic heart disease -
Core data management
P50HL-17646-04 0010 Study of ischemic heart disease -
Compliance in ischemic myocardium -Altered cardiac
performance (human, dogs)
MIA
PbOHl 1/646 04 0015 Study ol itchamic htart disHte
Prolectini ischemic myocirdium in palwnit with evolving
myocardial inlarclion
* P50HI I /(,48 04 OOOf) Study ol isthtmic heart diuiM
Vonlritular performance and myocardial perfusion in
obstructive coronary disease
P50H1 1/648 04 0021 Study ol ischemic heart diteait
Biventricular contractile retponies to acute myocardial
inlarction (mammals)
P50HI 1/648 04 0028 Study ol ischemic heart disease
Electrophysiology of sympathetic innervation in tissue
culture
P50HL 1/648 04 0031 Study ol ischemic heart disease
Ultrastruclural consequences ol myocardial ischemia (rat)
P50HL 1/651 04 0022 Ischemic heart disease specialized
center ot research Electrophysiology Mechanism and
pharmacology ol arrhythmias (human, dog)
P50HL 17651 04 0023 Ischemic heart disease specialized
center ol research Development ol multipurpose catheter
lor monitoring and electronic pacing
P50HL 17655 04 0001 Study ol ischemic heart disease
Intravenous nitroglycerin Ventricular lunction and inlarct
size (human, dog)
P50HL 1/665 04 0005 Study ol ischemic heart disease
Evaluation ol zone ot jeopardized myocardium in patients
with angina pectoris
P50HL 1766504 0012 Study of ischemic heart disease •
Myocardial ischemia Cardiovascular performance in the
conscious baboon and dog
P50HL 17665 04 0020 Study of ischemic heart disease -
Ischemic injury to myocardium during measured states of
ischemia (human)
** P50HL- 17665-04 0022 Study of ischemic heart disease
Effect of coronary revascularization on left ventricular
function (human)
P50HL-17665-04 0026 Study of ischemic heart disease ■
Anesthesia-Myocardial ischemia and hemodynamics in
coronary disease (human)
P50HL-17667-04 0018 Study of ischemic heart disease -
Arrhythmias in ischemic heart disease (human)
P50HL- 17669-04 0006 Ischemic heart disease center
(SCOR) Studies of hypoxic, acidotic and ischemic cardiac
muscle (dogs)
P50HL-1 7669-04 0007 Ischemic heart disease center
(SCOR) - Relationship between myocardial depression and
compliance (dogs, cats)
P50HL- 17669-04 0008 Ischemic heart disease center
(SCOR) - Segmental ventricular dysfunction during stress-
induced ischemia (dog. human)
** P50HL17670-04 0009 Study of ischemic heart disease
Surgical treatment of localized left ventricular dyssynergy
(human, dogs)
P50HL17670-04 0014 Study of ischemic heart disease -
Real time ultrasound imaging in ischemic heart disease
(human, dog)
P50HL-17670-04 0020 Study of ischemic heart disease -
Radionuclide evaluation of coronary artery disease (human,
dog)
P50HL-17682-04 0001 Study of ischemic heart disease ■
Studies in acute and chronic ischemic heart disease
(human)
P50HL-17582-04 0003 Study of ischemic heart disease -
Effects of myocardial revascularization in man
P50HL-17682-04 0013 Study of ischemic heart disease -
Chronic ischemic heart disease-Myocardial function and
metabolism (dogs, swine)
P50HL-17682-04 0014 Study of ischemic heart disease -
Myocardial ischemia -Instrumentation and technique (dogs,
baboons)
P50HL- 17682-04 0020 Study of ischemic heart disease ■
Nucleotide and nucleoside metabolism in ischemic
myocardium
M ROlHL-17993-04 Ventricular dynamics from surgically
inserted markers
ROlHL-17993-04 0001 Ventricular dynamics from
surgically inserted markers ■ Effects of aortocoronary
bypass graft surgery on ventricular function (human)
ROlHL-1799304 0002 Ventricular dynamics from
surgically inserted markers - Left ventricle function in
human cardiac allograft
ROlHL-17993-04 0003 Ventricular dynamics from
surgically inserted markers - Effects of pharmacologic
agents on left ventricular dynamics (human)
R01HL17993-04 0004 Ventricular dynamics from
surgically inserted markers ■ Exercise training following
coronary artery bypass graft surgery (human)
ROlHL-17993 04 0006 Ventricular dynamics from
surgically inserted markers - Atrial pacing in transplant
patients
ROlHL-17993-04 0007 Ventricular dynamics from
surgically inserted markers - Digitalis after coronary artery
surgery (human)
** ROlHL-17993-04 0009 Ventricular dynamics from
surgically inserted markers - Cardiovascular visualization in
surgery of growing heart (dogs)
ROlHL-17993-04 0010 Ventricular dynamics from
surgically inserted markers - Postoperative cardiovascular
visualization (human)
ROlHL-18053-03 Intracellular ionic activities in heart
muscle (frogs)
R01HL18538-03 The role of electrotonus in His-Purkinje
function (dog)
(contd)
•Excludes routine methodology OR covers only general projects which preclude
**0rientcd significanthi to above subject.
Indexing at the specific level.
M Grant has subprojects describing specific research aspects
See Appendix for investigator's name and grant number.
HEA
238
HEA
R01HL1868303 Left ventricle function in aortic
regurgitation (human)
ROlHL-1880504 0005 Sudden cardiac death and the
onset of myocardial infarction - Sudden death survivors -
Radionuclide studies (human)
Intercellular factors in function of
Energy output and efficiency of left
Ventricular dysfunction and cardiac
Cardiovascular pharmacodynamics in
Active prosthetic myocardium-Effects on
R01HL1890D03
cardiac cells
R01HL18933-03
ventricle (dog)
ROlHL-19203-03 Surgical approach to congenital heart
diseases (dogs, primates)
** ROlHL-1946003 Mechanics of the papillary muscle and
the left ventricle (cats, rabbits)
** ROlHL-20037-02 Left ventricular-aortic bypass and
composite prosthesis (sheep, swine, cattle)
ROlHL-20153-02 Intracellular pH and myocardial
electropharmacology (dogs, guinea pigs)
R01HL-20674-02 Evaluation of cardiac function with
radioactive tracers
R23HL-21196-02 Digitalis induced arrhythmia and NAO KO-
atpase activity (dogs)
** R23HL-21 197-02 Right ventricular contraction and
relaxation (dogs)
R23HL-21203 02 Effect of vasoactive agents on left-to-
right shunts (lambs)
** ROlHL-2131201 Sarcomere mechanics in disrupted
ventricular muscle (guinea pigs)
** R23HL-2 1462-02 Mechanical interactions between ventricle
arteries (dogs)
R01HL-2ie84-02 0004 Radionuclide infarct sizing and
therapy evaluation - Image analysis- Kinetics of infarction,
ventricular function (human, animal)
ROlHL-2 1690-02 Sequential multinuclide study of acute
infarction (human, dogs)
** ROlHL-21785-01 Left ventricular wall motion analysis
ROlHL-21985-01 Videoroentgenography in congenital heart
disease
" ROlHL-22152-02
surgery (dogs)
R23HL-22309-01
immature dogs
" ROlHL-22329-01
LV function (dogs)
R23HL-22787-01 Cardiac volume by biplane
echocardiography (human)
ROlHL-22894-01 Two dimensional ultrasound and cardiac
surgery (human, dogs)
** ROlHL-23624-01 Effect of drugs on ischemic cardiac cells
(dogs, guinea pigs, pigs)
ROlHL-23994-01 Biochemical properties of human cardiac
myosin
HEART ARREST
SEE HEART DISORDERS, HEART ARREST
HEART BLOCK
SEE HEART DISORDERS, ARRHYTHMIA, HEART BLOCK
HEART BYPASS (SHUNT) EXTRACARDIAC
ABNORMAL
SEE CONGENITAL ABNORMALITIES, CARDIOVASCULAR SHUNTS
ABNORMAL
HEART BYPASS (SHUNT) INTRACARDIAC
ABNORMAL
SEE CONGENITAL ABNORMALITIES, HEART SEPTAL DEFECTS
HEART BYPASS SURGICAL, PARTIAL OR TOTAL
SEE CARDIOVASCULAR SURGERY, CIRCUUTORY ASSIST,
HEART BYPASS SURGICAL
HEART CATHETERIZATION
SEE HEART DISORDERS DIAGNOSIS, HEART
CATHETERIZATION*
HEART CELLS
ROlHL-04457-20 Cellular aspects of active transport (fish,
rabbits, anurans, turtles)
P01HL-06285-18 0164 Cardiovascular-respiratory
physiology and biochemistry - CPK MB isoenzyme
concentration to quantify infarct size (human, animals)
POlHL-0628518 0178 Cardiovascular-respiratory
physiology and biochemistry - Biochemical regulation of
hypertrophy (rats, rabbits)
** POlHL-06285-18 0179 Cardiovascular-respiratory
physiology and biochemistry Regulation of myocardial cell
growth (rats, chick embryo)
R01HL09489-13 Myocardial lipid metabolism and
regulation (rats)
** ROlHL-10018-11 Effect of aging on beating heart cells in
culture (rats)
** POlHL-1 1351-12 0005 Cellular and molecular
mechanisms of myocardial function - Electrophysiology of
cardiac muscle (rats)
POlHL-11351-12 0009 Cellular and molecular
mechanisms of myocardial function - Myocardial membrane
surface coat (rats, rabbits)
POlHL-11351-12 0011 Cellular and molecular
mechanisms of myocardial function - Comparative
contractile tissue studies (animals)
POlHL-11351-12 0018 Cellular and molecular
mechanisms of myocardial function - Quantitative
localization of electrolytes in cardiac tissue
POIHL 12157 11 0037 Functions and mechanisms of cell
membrane ion transport Developing structure of heart
cells in tissue culture
POIHL 12157 11 0055 Functions and mechanisms of cell
membrane ion transport - Growth and development of
synthetic strand heart cells in culture (chick embryo)
POlHL-12157-11 0056 Functions and mechanisms of cell
membrane ion transport - Isotopic fluxes in synthetic
strands of heart cells (chick embryo)
ROlHL-12486-10 Structure-function correlation in the
atrium (rabbits)
Physiologic pharmacology and its
Myocardial cells in tissue culture
Regulation of the circulation in
Ionic basis of depolarization (rats,
POIHL 12738-10 0135
clinical applications
(rats, chick embryo)
POlHL-14388-07 0168
pathological states
tissue culture)
ROlHL-14832-06 Myocardial cells-Autonomic and rhythmic
mechanisms (chick embrvo, rats)
ROlHL-14990-07 Lipid transport in avian species
(chickens)
ROlHL-15567-05 Cardiovascular phosphoinositide
metabolism (rats)
ROlHL-15740-06 In vitro studies on heart cell function
(rats)
ROIHL 16010-16 Cellular basis of cardiac contractility
(frogs)
ROIHL 16507-04 Heart cell interactions and cell junction
biogenesis (mice, rats, rabbits)
ROlHL-16567-04 Differentiation of the heart-cell
membrane (mice, chick)
P60HL-17269-04 0003 National heart and blood vessel
research and demonstration center - Atherosclerosis -Fatty
acid metabolism in cardiovascular tissue (human, chicken)
P60HL-17269-04 0020 National heart and blood vessel
research and demonstration center - Nucleic acid and
protein metabolism in growth and development of heart
(rat)
P60HL-17269-04 0021 National heart and blood vessel
research and demonstration center - Growth and
development of heart-Ultrastructure (dog, guinea pig, rat,
cat)
ROIHL 17376-04 Analysis of Z bands In heart by optical
diffraction (mammals)
P50HL-17648-04 0025 Study of ischemic heart disease -
Destruction and repair of cardiac muscle cell constituents
(rat)
P50HL-1764804 0026 Study of ischemic heart disease -
Control of muscle cell proliferation (organ culture)
P50HL-17648-04 0027 Study of ischemic heart disease -
Phospholipid metabolism following cardiac injury and
repair (rat)
P50HL-17648-04 0028 Study of Ischemic heart disease -
Electrophysiology of sympathetic Innervation in tissue
culture
P50HL-17648-04 0031 Study of ischemic heart disease -
Ultrastructural consequences of myocardial ischemia (rat)
P50HL-1 7667-04 0012 Study of ischemic heart disease -
Biochemistry of normal and ischemic heart-Glycolysis (rats)
P50HL- 176 70-04 0023 Study of ischemic heart disease -
Energy metabolism in acute myocardial ischemic injury
(dogs)
P50HL-17682-04 0018 Study of ischemic heart disease -
Biochemistry of ischemia-Heart cell and organ culture
(mice, rats, cattle)
P50HL-1 7682-04 0023 Study of ischemic heart disease -
Core cell and organ culture laboratory (mice)
POlHL-17813-04 0007 Lung disease and the oxygenation
of blood and tissue - Studies on the function of myoglobin
(dogs)
ROlHL-1800305 Digitalis-Mechanism and reversal studies
(dog, sheep, duck, guinea pig, human)
ROlHL-18053-03 Intracellular ionic activities in heart
muscle (frogs)
ROlHL-181 76-02 Effect of thyroid hormone on cultured
cardiac cells (rats)
R01HL-18560-03 Cardiovascular adaptation to stress
(miniature swine)
ROlHL-18647-03 Ischemic myocardial injury in cultured
heart cells (rats)
POlHL-18708-03 0007 Oxygen, energy and contractility in
cardiac tissue - Surfaces, energy requirements, and
contractile proteins of cardiac cell in vitro
POlHL-18708-03 0008 Oxygen, energy and contractility in
cardiac tissue - Cardiac cell culture facility
POlHL-18708-03 0009 Oxygen, energy and contractility in
cardiac tissue - Regulation of oxygen utilization of cardiac
tissue (rats, rabbits)
POlHL-18708-03 0010 Oxygen, energy and contractility in
cardiac tissue - Tissue oxygen utilization (rats, dogs)
R01HL-I87 11-03 Electrophysiology of heart cells (rats,
chicks)
ROlHL-18798-04 0001 Nervous and ionic factors in
sudden cardiac death - Potassium loss during myocardial
ischemia (rabbits)
ROlHL-18900-03
cardiac cells
ROlHL-18943-03
ROlHL-19138-03
cells (mammals)
ROlHL-19299-03
Intercellular factors in function of
Contractile activity of single cardiac cells
Contractile activation of skinned cardiac
Myoglobin and oxygen supply to heart
and muscle cells (rats, pigeons)
ROlHL-19782-02 Pharmacologic studies on the ischemic
heart (dogs)
ROlHL-19848-02 Contractile activation by rapid
temperature jumps (frogs)
ROlHL-20 153-02 Intracellular pH and myocardial
electropharmacology (dogs, guinea pigs)
** ROIHL 20254-02 Probes of heart and nerve membranes-
Fluorescent dyes
** ROlHL-20394-03 Complement activation by heart
subcellular membranes (human, dog)
ROlHL-20533-09 Pathogenesis of rheumatic fever (human,
rabbits)
POlHL-20592-02 0003 Cell biology of cardiac and
skeletal muscle - Cellular magnesium and anion activities
in ion-specific microelectrodes (frogs)
POIHL 20592-02 0004 Cell biology of cardiac and
skeletal muscle - Excitation, conduction and contraction-
Modelling in Purkinje fibers
POlHL-20592-02 0006 Cell biology of cardiac and
skeletal muscle - Permeability and ultrastructure of cardiac
nexuses (rabbits, cattle, rats)
POlHL-20592-02 0013 Cell biology of cardiac and
skeletal muscle - Sarcoplasmic reticulum in skinned
muscle cells (frogs)
** ROlHL-20643-02 Analysis of heart cell contraction (rats)
" ROlHL-20708-02 Voltage clamp of embryonic heart cell
aggregates (rat and chick embryos) r
** ROlHL-20793-02 Phospholipids and cardiac receptor
function
** POlHL-20984-02 0004 Cellular mechanisms in cardiac
hypertrophy - Myofibril accumulation in cardiac and
vascular muscle cells in hypertrophy
** ROlHL-21 136-02 Ion activities and transport in cardiac
muscle cells (sheep)
** R01HL-21342-02 Isolation and analysis of sodium channel
from heart (frogs)
ROlHL-21371-02 Energy loss microanalysis of myocardial
cations
ROlHL-21751-02 0001 Thallium and antimyosin in
ischemia and infarction - In vitro models of ischemia and
infarction (rats, mice)
ROlHL-21995-01 Protein phosphorylation and adrenergic
effects
** ROlHL-22101-02 Hormone-substrate interaction in diabetic
myocyte (dogs, rats)
ROlHL-22135-01 Control of calcium fluxes across cardiac
membranes (dogs, rabbits, guinea pigs)
** ROlHL-2223901 The molecular basis of electrical
excitability (chick embryos, rats)
" R23HL-22490-01 Neurotransmitter receptors of cultured
heart cells
** ROIHL-22562-02 Mechanism of cardiac action potential
propagation (tunicates)
•* ROlHL-22568-01 pH effect in heart cells-Influence of
cardiac drugs (tissue culture, rats)
** R01HL-22664-0I Regulation of myocardial cell growth
(rats, guinea pigs)
R23HL-22775-01 Muscarinic receptors In the developing
heart (chick embryo)
ROlHL-23 128-01 Cardiac contractility -Ischemia and
hypoxia (rabbits, rats)
ROlHL-23138-01 Myocardial ischemia (dogs, rats, chick
embryo)
ROlHL-23142-01 Mechanisms of membrane injury in
myocardial ischemia (dog)
ROlHL-23161-01 0001 Biology of myocardial ischemia -
Mitochondrial lipid metabolism and cardiac ischemia (rat,
dog)
ROlHL-23166-01 Pathology of mitochondria in ischemic
myocardium (rats, cattle)
** R01HL-23618-0I Substrate metabolism in isolated
myocytes in shock (dogs, rats, guinea pigs)
R01HL-2362e-01 A study of the regulation of myocardial
hypertrophy (rats)
HEART CIRCULATION
SEE ALSO HEART DISORDERS, CORONARY, MYOCARDIAL
ISCHEMIA AND HYPOXIA
SEE ALSO HEART REVASCULARIZATION
SEE ALSO HEART VESSELS
** ROlHL-03 180-21 Relation of lymphatics to
cardiopulmonary function (dogs)
** ROlHL-03290-22 Controls of cardiac and vascular smooth
muscles (cats, rats, dogs)
M POlHL-04664-18 Cardiovascular and lung dynamics
POlHL-04664-18 0001 Cardiovascular and lung dynamics
- X-ray projection image videodensitometry (dogs)
** POlHL-04664-18 0004 Cardiovascular and lung dynamics
- X-ray cross section imaging of the circulation (dogs)
ROlHL-05694-20 Functional pathology of cardiovascular
disease (human)
R01HL-05875-I8 Pathologic metabolic and physiologic
studies of heart (human, dogs, cats)
** ROlHL-05883-18 0008 Reflex control of resistance and
capacitance vessels - Oxygen consumption of the
chronically denervated dog heart
** ROlHL-06143-18 Response of the totally denervated heart
to exercise (dogs)
POlHL-06285-18 0131 Cardiovascular-respiratory
physiology and biochemistry - Fetal heart development and
ventricular outflow obstruction (lambs)
(contd)
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
••Qnerrted significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
HEA
Aortocoionat>
Coronary flow
P0IH10628S 18 0143 Cardiovascular respiritory
physiology and biochamistiy Myocardial ischemia (human.
dogs, lambs)
POIHL 06308 18 Mechanisms and therapy ol circulatory
disease
POIHI 06308 18 0011 Mechanisms and therapy ol
circulatory disease Blood How and electrical dysfunction
In vantnculai arrhythmia (human)
IHllHL 06308 18 001? Mechanisms and therapy of
circulatory disease Echocaidiographic evaluation of
hemodynamics ol arrhythmia (human)
POIHL 06308 18 0029 Mechanisms and therapy of
circulatory disease Characteriiation ol the patient with
recurrent ventricular arrhythmias
POIHL 06308 18 0037 Mechanisms and therapy of
circulatory disease Electrophysiology, blood flow, and ANS
in ventriculai tibrillation (dogs)
POIHL 06308 18 0038 Mechanisms and therapy of
circulatory disease Electrophysiology ol ventricuair
arrhythmias associated with ischemia (dogs)
P01HLD6312 17 Surgical cardiology
POIHL 06312 17 0013 Surgical cardiology
vein bypass grafting (human)
P01HL06312 17 0028 Surgical cardiology
in the transplanted denervated heart (dogs)
POIHL'06312 17 0044 Surgical cardiology The limits of
topical cardiac hypothermia with ice chips (rats)
POIHL 06314 17 0065 Immunologic mechanisms in
cardiovascular disease Transplantation biology and
clinical transplantation
P01HL06370'17 0014 Cardiopulmonary and renal
pathology research center Quantitative morphology in
cardiac disease (human, rats, dogs)
P01HL06664 17 0034 Cardiopulmonary (unction in
remediable vascular disease - Role of hyperosmolar agents
in ischemic heart disease (dogs)
ROlHL-07139'17 Cardiodynamics and metabolism of
congestive failure (human, dogs)
POlHL-07293-17 0043 Noninvasive cardiovascular
measurements - ECHODoppler instrumentation for cardiac
measurements (human)
P01HL07293-17 0045 Non invasive cardiovascular
measurements - Cardiac scanner transducer position
locating systems (human)
POlHL-07293-17 0046 Mon-invasive cardiovascular
measurements - Cardiac scanner signal processors
POlHL-07293-17 0047 Non-invasive cardiovascular
measurements - Cardiac scanner system software
P01HL07293'17 0048 Non-invasive cardiovascular
measurements - Cardiac scanner recording and display
systems component
POlHL-07293-17 0049 Non-invasive cardiovascular
measurements - Cardiac scanner engineering evaluation
and error analysis
POlHL-07293-17 0050 Non-invasive cardiovascular
measurements - Cardiac dimensions measurements
engineering evaluation and error analysis
■ POlHL-07293-17 0051 Non-invasive cardiovascular
measurements - Physiologic evaluation of duplex scanner
(dogs)
POlHL-07293-17 0052 Non-invasive cardiovascular
measurements - Clinical evaluation of the duplex scanner
(human)
' POlHL-07293-17 0059 Non-invasive cardiovascular
measurements - Intracardiac blood flow measurement
(human)
' POlHL-07896-15 0054 Environmental biomedical research
program • Myocardial effects of hemorrhagic shock (dogs)
' POlHL-07896-15 0059 Environmental biomedical research
program - Hyperoxygenation at elevated atmospheric
pressure on myocardial blood flow (dogs)
' ROlHL-08659-14 Myocardial performance and metabolism
In the newborn (sheep)
POlHL-08682-15 0036 Regulation of the cardiovascular
system • Electrolyte transport in myocardium with
hemorrhagic shock (rats)
ROlHL-08696-15 0020 Orthotopic heart transplantation -
Complete cardiopulmonary transplantation (dogs)
• POlHL-08805-15 0050 Regulation of ventilation and
pulmonary circulation - Right ventricular mechanics (dogs)
POlHL-08899-14 0025 Tolerance to respiratory gases in
health and disease - Effects of oxygen on cardiopulmonary
gas transport functions (dogs)
ROlHL-09914-13 The myocardium in diabetes mellitus
(dogs, monkeys)
• POlHL-10342-13 0008 The integrated function of
respiration and circulation - Respiratory mechanics and the
circulation (human, dogs)
' ROlHL-10384-13 Blood flow and nucleotide metabolism
(animals)
• POlHL-10436-13 0002 A multidisciplinary study of
congenital heart disease - Myocardial performance,
metabolism and ultrastructure (human, cats, rats)
POlHL-10436-13 0014 A multidisciplinary study of
congenital heart disease - Cardiovascular pharmacology
(dog)
' POlHl-10539-12 0070 Pathophysiology of circulation
Effects of hypertension on myocardial blood flow after
coronary occlusion (dogs)
POlHL-11310-12 Mechanisms of cardiovascular disease
' POlHL-11310-12 0060 Mechanisms of cardiovascular
disease - Effect of left atrium on the circulation-Simulation
339
POIHI 11310 1? 0063 Mechanisms of cardiovascular
disease Myocaidial function, metabolism and cellular
integrity alter heait surgery (dogs)
POIHL 11310 I? 0068 Mechanisms of cardiovascular
disease Pharmacological intervention and myocarcial
oxygen consuption (human, dogs)
POIHI 11310 1? 00/6 Mechanisms ol cardiovascular
disease Ttatment ol depressed cardiac output following
heart surgery (children, puppies)
POIHL 11310 12 0080 Mechanisms ol cardiovascular
disease Metabolism ol the hypertrophied myocardium
(human)
POIHL 11310 12 0082 Mechanisms of cardiovascular
disease Myocardial function in adult congenital heart
disease (human)
POIHL 11351 12 Cellular and molecular mechanisms of
myocardial function
POIHL 11351 12 0020 Cellular and molecular
mechanisms of myocardial function Electrophysiology of
cultured heart cells
ROIHL 11876 11 Regional myocardial blood flow and
metabolism (dogs, swine)
ROIHL 11906 II Comparative study of heart function
(cats, rats, hedgehogs, squirrels)
ROlHL-12322 10 Extrinsic factors influencing myocardial
performance (dogs, swine)
POIHL 12373 10 Cardiopulmonary physiology and
pathophysiology
POIHL 12373 10 0020 Cardiopulmonary physiology and
pathophysiology Hospitalization and patient care
ROIHL 12415 10 Evaluation of left ventricular function
(dogs, rabbits)
Physiologic pharmacology and Its
Blood rheology in coronary heart
HEA
POIHL 12738-10 0069
clinical applications
disease (dogs)
POlHL-12738-10 0071
clinical applications
Physiologic pharmacology and its
lABP patient management in
ventricular power failure (human)
POIHL 12738 10 0076 Physiologic pharmacology and its
clinical applications Pediatric cardiac electrophysiology
and pharmacology (human, dogs)
POIHL 12738-10 0081 Physiologic pharmacology and its
clinical applications - Ultrastructural and electrophysiologic
alteration of myocardium (human, dogs)
POlHL-12738-10 0092 Physiologic pharmacology and its
clinical applications - Subendocardial ischemia following
open heart surgery (human)
POlHL-12738-10 0111 Physiologic pharmacology and its
clinical applications ■ Cardiovascular pharmacology (dogs)
P01HL12738-10 0122 Physiologic pharmacology and its
clinical applications - Coronary perfusion of beating and
fibrillating hearts (dogs)
P01HL12738-10 0123 Physiologic pharmacology and its
clinical applications - Ventricular assistance and
preservation (human, dogs)
ROlHL-12777-09 Mechanisms in cardiac performance
(dogs, human)
ROlHL-13036-08 Coronary thrombosis-Effects on
myocardium and in vivo detection (dogs, monkeys)
POlHL-13108-09 Clinical heart transplantation
POlHL-13108-09 0003 Clinical heart transplantation -
Endomyocardial biopsy pathology
POlHL-13108-09 0008 Clinical heart transplantation -
Physiology and pharmacology of the transplanted human
heart
POlHL-13108-09 0020 Clinical heart transplantation -
Autonomic neural studies in the denervated heart (human)
POlHL-13108-09 0021 Clinical heart transplantation -
Autonomic reflex regulation of ventricular function (human)
POlHL-13108-09 0022 Clinical heart transplantation -
Studies on cardiac receptors (human)
POlHL-13108-09 0023 Clinical heart transplantation -
Adaptive mechanisms of the denervated heart (human)
ROlHL-13257-09 Inhalation anesthesia on myocardial
metabolism (dogs, swine, human)
POlHL-13480-09 0028 Cardiac electrophysiology - Stress
electrocardiography (human, dogs)
POlHL-13737-07 0027 Assisted circulation - Optimization
of cardiac assistance (dogs)
POlHL-13737-07 0033 Assisted circulation - Autologous
bioprosthetic grafts for coronary artery bypass surgery
(human, dogs)
POlHL-13737-07 0037 Assisted circulation - Clinical
measurement of blood flow through aorto-coronary vein
bypass graft
POlHL-13851-16 Cyclotron produced isotopes in biology
and medicine (human, animals)
ROlHL-14148-07 0009 The regional circulations -
Myocardial circulation in hypertension and atherosclerosis
(human)
P50HL-14236-05 0002 Prevention of premature
arteriosclerosis - Myocardial blood flow in patients with
coronary artherosclerosis
POlHL-14388-07 Regulation of the circulation in
pathological states
POlHL-14388-07 0161 Regulation of the circulation in
pathological states - Heterogeneity of left ventricular
perfusion in awake dogs
POlHL-14388-07 0162 Regulation of the circulation in
pathological states - Phasic coronary flow and myocardial
perfusion in aortic regurgitation (dogs)
POIHI 14388 0/ 0161
pathological ^tale^
vessels (dogs)
POIMt 14388 0/ 0164
pathulogK.dl ■,lalfr'>
POIHI 143880/ 01/?
pathological states
Regulation ol the circulation m
Adrenergic receptori in coronary
1 jn ol the c .1
Reflex control of venous tone (human.
Regulation ol the circulation in
Choline acetyltranslerase activity
Regulation of the circulation in
Myocardial ischemia and infarction in
Regulation of the circulation in
Pharmacology ol the coronary
Regulation of the circulation in
Experimental myocardial infarction
Environmental influences on
Control of the
Regulation ol the circulation in
Hypnckinetic heart syndrome (human)
Regulation ol the circulation m
cAMP dependent piolein kinase Irom
heart and vauulai smooth muscle (guinea pigs)
POlHt 14388 0/ 01/3 Regulation ol the circulation in
pathological stales Mechanisms ol cardiac myosin AIF'ase
POIHL 14388 0/ 01/5 Regulation of the circulation in
pathological states Functional studies ol selected proteins
Irom cardiac muscle
POIHL 14388 0/ 0179 Regulation of the circulation in
pathological slates Cultured muscle cells and their cross
innervation in vitro (rats, sheep)
POIHL 14388 0/ 0183 Regulation ol the circulation in
pathological stales Vasopre-s' n- cardiovascular
regulation (dogs ■ '
POIHL 1438807 Ola:,
pathological states
rabbits, dogs)
POIHL 1438807 0211
pathological states
(rats)
POIHL 1438807 0219
pathological states
animals (dogs)
POIHL 14388-07 0220
pathological states
circulation in man
POlHL-14388-07 0221
pathological states -
(dogs)
POlHL-1441407 0015
cardiorespiratory and cellular functions
cardiovascular system (dogs)
ROlHL-14644-05 Optimization diastolic augmentation and
systolic sink (dogs)
ROIHL 15016-07 New concepts in cardiac ultrasound
technology (human)
POIHL 15194 07 Pathophysiology of cardiopulmonary
dysfunction
POlHL-15194-07 0001 Pathophysiology of
cardiopulmonary dysfunction Coronary circulation, venous
drainage and collateral flow (human, dogs)
POlHL-15194-07 0017 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation and
effects of arteriographic lesions on flow (human)
POlHL-15194-07 0018 Pathophysiology of
cardiopulmonary dysfunction Coronary circulation,
metabolic demand and vasodilatory reserve (human, dogs)
POlHL-15194-07 0019 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation, bypass
grafts and diastolic driving pressure (human, dogs)
POlHL-15194-07 0020 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation in
arteriographically normal arteries (human)
ROlHL-15416-06 Cardiovascular control in normal and
disease states (dogs, baboons)
ROlHL-15444-06 Neonatal development of adrenergic
receptor mechanisms (pigs)
R01HL-15498-06 Effects of physical training on heart
(rats)
R01HL-15522-05 Influence of mannitol on ischemia
cardiac muscle (dogs, cats, rats)
ROlHL-15681-06 Coronary flow studies of partially
obstructed vessels (dogs)
ROIHL- 15758-06 Catecholamine release in the heart
(dogs)
ROlHL-15983-04 Regional myocardial blood flow (dogs)
POlHL-16117-05 0007 Ion movements and membranes in
cardiovascular control - Physiological and molecular
properties of ionophores (dogs, rabbits)
ROlHL-16236-04 Detailed characteristics of coronary blood
flow (horses, dogs, calves)
ROIHL- 16292-05 0002 Surgery and non-obstructive
coronary insufficiency - Effects of hypothermia during
cardiopulmonary bypass (dogs)
ROlHL-16292-05 0010 Surgery and non-obstructive
coronary insufficiency - Effects of exercise on flow
distribution (dogs)
ROlHL-16292-05 0017
coronary insufficiency
(human)
ROlHL-16292-05 0018
coronary insufficiency
Surgery and non-obstructive
Cardiopulmonary resuscitation
*Excludes .-outine methodokigy OR covers only general projects which preclude indexing at the specific level.
**Onented significantly to above subject.
Surgery and non-obstructive
Unavoidable subendocardial
perfusion caused by venting and hypothermia (dogs)
ROlHL-15292-05 0019 Surgery and non-obstructive
coronary insufficiency - Distortion of subendocardial vessels
in infant hearts (dogs)
ROlHL-16292-05 0020 Surgery and non-obstructive
coronary insufficiency - Limitation of transthoracic ECG in
detecting subendocardial ischemia (dogs)
ROlHL-16292-05 0021 Surgery and non-obstructive
coronary insufficiency - Pulsatile assistance on
subendocardial perfusion during bypass (dogs)
ROIHL 16412-04 Release of nucleosides from the ischemic
heart (human, dogs)
R01HL-16511-04 Sympathetic afferent activity of cardiac
origin (dogs, monkeys)
(contd)
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
HEA
240
HEA
ROlHL-16657-06 Innervation of coronary arteries and heart
(rats)
R01HL16760-05 Dynamic control of coronary blood flow
(dogs)
POIHL 16910-05 0002 Regulation of the peripheral
circulation - Coronary circulation (dogs)
P01HL16910-05 0006 Regulation of the peripheral
circulation - Regulation of blood flow distribution (baboons,
dogs)
P60HL17269-04 0023 National heart and blood vessel
research and demonstration center - Cardiovascular
pharmacology-Ischemia, shock and heart failure (dog, cat,
rat)
P60HL- 17269-04 0026 National heart and blood vessel
research and demonstration center - Dynamics of ischemic
heart disease (human, dog)
ROlHL-17403-03 Metabolic control of cardiac output
(dogs)
ROlHL-17459-03 Myocardial ischemia (dogs)
R01HL17479-04 Blood storage-The production of
cardiotoxic material (dogs, human, swine)
ROlHL-1759103 Development of electromagnetic
rheoangiography (human, dogs)
P50HL- 17646-04 0005 Study of ischemic heart disease ■
Biochemical markers and mediators of myocardial ischemic
injury
P50HL- 17646-04 0012 Study of ischemic heart disease -
Role of microcirculation in progression of myocardial
ischemic injury (rat)
P50HL 1764604 0013 Study of ischemic heart disease
Maintenance of myocardial vascular integrity after
revascularization (dogs)
P50HL-1764604 0014 Study of ischemic heart disease -
Progression of ischemic injury in conscious dogs (also
rabbits)
P50HL-1 7648-04 0004 Study of ischemic heart disease ■
Radionuclide imaging studies (human, pig)
' P50HL-1 7648-04 0006 Study of ischemic heart disease -
Ventricular performance and myocardial perfusion in
obstructive coronary disease
P50HL-1 7648-04 0011 Study of ischemic heart disease ■
Surgical treatment for acute myocardial ischemia (human,
dogs)
P50HL-1764804 0012 Study of ischemic heart disease -
Retrograde coronary venous perfusion -Acute myocardial
ischemia
P50HL-17648-04 0013 Study of ischemic heart disease ■
Fate of bypassed and bypassing vessels (dogs)
P50HL-17648-04 0021 Study of ischemic heart disease -
Biventricular contractile responses to acute myocardial
infarction (mammals)
P50HL-17648-04 0034 Study of ischemic heart disease ■
Data management-Hemodynamic data
' P50HL17651-04 0002 Ischemic heart disease specialized
center of research - Reduction of myocardial ishemic injury
by pharmacologic agents (human, dog)
P50HL17651-04 0016 Ischemic heart disease specialized
center of research - Retroperfusion of coronary venus
circulation with therapeutic agents (dogs)
■ P50HL1765104 0037 Ischemic heart disease specialized
center of research ■ Measurement of coronary venous
outflow by thermodilution (human)
P50HL-17651-04 0038 Ischemic heart disease specialized
center of research - Cardiothermography (human, dog)
P50HL-1765104 0043 Ischemic heart disease specialized
center of research - Gradual reperfusion following acute
coronary occlusion (dog)
P50HL-1765104 0045 Ischemic heart disease specialized
center of research - Peripheral vascular studies-
Pharmacology (dogs, human)
P50HL-1 7655-04 0001 Study of ischemic heart disease -
Intravenous nitroglycerin-Ventricular function and infarct
size (human, dog)
P50HL- 17655-04 0006 Study of ischemic heart disease -
Evaluation of coronary artery bypass graft surgery (human)
P50HL1765504 0011 Study of ischemic heart disease ■
Core facility-Cardiovascular nuclear medicine (human, dog)
* P50HL- 17655-04 0014 Study of ischemic heart disease ■
Blood flow and gas tension in myocardial ischemia and
infarction (dog, monkey)
P50HL 17665-04 0012 Study of ischemic heart disease -
Myocardial ischemia -Cardiovascular performance in the
conscious baboon and dog
* P50HL1766504 0021 Study of ischemic heart disease -
Identification, prevention -Myocardial ischemia In
cardiopulmonary bypass (dog)
P50HL-1766504 0027 Study of ischemic heart disease -
Positron imaging of regional myocardial perfusion (human,
dog)
P50HL1 7667-04 0045 Study of ischemic heart disease •
Pathology of myocardial ischemic necrosis (human)
P50HL-1 7669-04 0006 Ischemic heart disease center
(SCOR) - Studies of hypoxic, acidotic and ischemic cardiac
muscle (dogs)
P50HL1 7669-04 0008 Ischemic heart disease center
(SCOR) • Segmental ventricular dysfunction during stress-
induced ischemia (dog, human)
* P50HL- 17669-04 0012 Ischemic heart disease center
(SCOR) - Circulatory assistance (human, dog)
* P50HL-17670-04 0006 Study of ischemic heart disease -
Assessment of coronary artery hemodynamics and
myocardial blood flow (human)
P50HL-17670-04 0009 Study of ischemic heart disease ■
Surgical treatment of localized left ventricular dyssynergy
(human, dogs)
PS0HL-I7670-04 0011 Study of ischemic heart disease -
Pharmacology of ischemic myocardium (dogs)
P50HL1767004 0015 Study of ischemic heart disease -
Radionuclide studies of myocardial Ischemia (human)
P50HL-17670-04 0020 Study of ischemic heart disease ■
Radionuclide evaluation of coronary artery disease (human,
dog)
P50HL-1767004 0021 Study of ischemic heart disease -
Enzymatic evaluation of acute myocardial infarction (dogs)
P50HL-1768204 0003 Study of ischemic heart disease -
Effects of myocardial revascularization in man
P50HL-1 7682-04 0005 Study of ischemic heart disease -
Regional myocardial perfusion deficits and segmental
contraction disorders in man
P50HL-17682-04 0011 Study of ischemic heart disease -
Nuclear medicine core unit (human, dogs, rabbits, mice)
P50HL-1768204 0014 Study of ischemic heart disease ■
Myocardial ischemia -Instrumentation and technique (dogs.
baboons)
P50HL-1768204 0015 Study of ischemic heart disease ■
Acute myocardial ischemia and Infarction and their
reversibility (dogs, baboons)
P50HL- 176 8204 0016 Study of ischemic heart disease ■
Endurance exercise -Prevention and rehabilitation in
ischemic heart disease (pig)
P50HL1768204 0020 Study of Ischemic heart disease -
Nucleotide and nucleoside metabolism in ischemic
myocardium
P50HL- 17682-04 0021 Study of ischemic heart disease -
Prostaglandin biosynthesis in blood vessels from ischemic
myocardium (rat, sheep)
ROlHL-1 7736-04 Metabolic change during cardiac
ischemia (rats, dogs)
Studies of myocardial reactive hyperemia
Effects of exercise on the coronary
dog)
Computational methods in cardiac fluid
R01HL1775903
(dogs, human)
ROlHL-1780904
vasculature (rat
ROlHL-17859-04
dynamics
ROlHL-1789504 Myocardial function and metabolism
following ischemia (rats)
ROlffL-17907-04 Brain regulation of cardiac arrhythmia
(pigs, cats, rats)
ROIHL 17954-03 Narcotics and the circulation (human,
dogs, pigs, monkeys)
ROlHL-1799304 0002 Ventricular dynamics from
surgically inserted markers - Left ventricle function in
human cardiac allograft
ROlHL-17993-04 0003 Ventricular dynamics from
surgically inserted markers - Effects of pharmacologic
agents on left ventricular dynamics (human)
R01HL17993-04 0006 Ventricular dynamics from
surgically inserted markers - Atrial pacing in transplant
patients
ROlHL-18024-03 Regional myocardial flow and function
relationships (dogs)
ROlHL-18060-04 Exercise and coronary atherosclerotic
heart disease (monkeys)
ROlHL-18190-03 Myocardial blood flow in acute
myocardial infarction (human, dogs)
ROlHL-18204-03 Regional blood flow in viral myocarditis
(turkeys)
ROlHL-18288-04 Intraoperative protection of the
myocardium (dogs, rats)
R01HL-18328-03 Hemoglobin function and tissue
oxygenation (human, dogs)
ROIHL- 184 60-01 Effects of prolonged hypoperfusion on the
myocardium (rabbits)
ROlHL-18468-03 The distribution of flow in the
myocardium (dog, pig)
R01HL18492-03 Measurement of regional coronary flow
reserve (human, dogs)
ROlHL-18537-04 Regional blood flow after acute
myocardial injury (dogs)
ROlHL-18599-02 Cardiovascular pharmacology of
ionophores (dogs)
ROlHL-1862904 Influence of aging and hypertension on
the myocardium (rats)
POlHL-1864603 0010 Studies basic to heart
transplantation - Development and study of a heart
preservation chamber (dogs, sheep)
' POlHL-18708-03 0009 Oxygen, energy and contractility in
cardiac tissue - Regulation of oxygen utilization of cardiac
tissue (rats, rabbits)
ROlHL-18795-04 Ischemic arrhythmias-Effect of
autonomic tone (dogs, rats, guinea pigs)
ROlHL-18805-04 0003 Sudden cardiac death and the
onset of myocardial infarction - Prediction from clinical and
laboratory assessments (human)
' ROlHL-18805-04 0005 Sudden cardiac death and the
onset of myocardial infarction • Sudden death survivors-
Radionuclide studies (human)
R01HL18933-03 Energy output and efficiency of left
ventricle (dog)
' ROlHL-18979-02 Mechanisms in local regulation of
coronary flow (rabbits)
' ROlHL-19135-04 Heterogeneity of regional myocardial
blood flow (dogs)
ROlHL-19182-03 Surgical aspects of myocardial
hypertrophy (dogs)
ROlHL-19202-03 Adenosine, prostaglandins in relation to
coronary flow (guinea pigs)
ROlHL-19218-03 Local regulation of coronary flow by
prostaglandins (rabbits)
ROlHL-19275-03 Characterization of collateral blood
vessels (dogs)
R01HL1937003 Coronary capillary exchange-The effects
of ischemia (dogs, sheep)
ROlHL-19398-03 Regional conduction abnormalities and
arrhythmias (dogs)
ROlHL-19414-03 Protection of myocardium during cardiac
surgery (dogs, cats, human)
ROIHL 19451-03 Functional characteristics of the left
heart
ROlHL-19451-03 0004 Functional characteristics of the
left heart - Quantitative coronary arteriography (human)
POlHL-19737-02 0007 Cellular and molecular aspects of
respiratory physiology - Average oxygen tension of tissue
using radioisotopes (dogs)
ROlHL-1993702
infarction (dogs)
ROlHL-20080-02
(dogs)
ROlHL-20163-02
Vasodilators in experimental myocardial
Surgically induced myocardial edema
Competitive coronary flow in native and
graft vessels (dog)
Pathogenesis of cardiac hypertrophy
Regulation of coronary arterial smooth
ROlHL-20190-02
(dogs)
ROlHL-20196-02
muscle
ROlHL-20206'02 Carbohydrates-nucleotides and adrenergic
interactions (rabbits, cats, rats)
ROlHL-20226-02 Cardiac bypass and coronary collateral
physiology (dogs)
ROlHL-20253-02 Effects of exercise on the heart and its
blood supply (dogs)
ROlHL-20283-02 Maintenance of cellular integrity in
ischemic hearts (cats)
ROlHL-20286-02 Interventions to improve cardiac function
in ischemia (dogs)
ROlHL'20356-02 Development and evaluation of an
artificial heart (calves)
ROlHL-20399-03 Vascular control in experimental diabetes
mellitus (dog)
ROlHL-20401-03 Relationship of insulin to catechol
cardiomyopathy (rabbit, pig)
ROlHL-20426-03 Myocardial function in diabetes mellitus
(dog, rat)
R0IHL-2047e-03 Effects of diabetes on cardiac
performance (rat)
POlHL-20552-02 0004 The development and regression of
cardiac hypertrophy - Ventricular function in experimentally
induced hypertrophy (hogs, sheep, baboons)
ROlHL-20572-02 0003 Hemodynamic relations to
metabolism in hypertension - Cardiac output and organ
blood flow in hypertension (rats)
ROlHL-20597-02 Electrophysiologic correlates of
myocardial ischemia (human, dogs, rabbits)
ROlHL-20598-03 The coronary vascular response to
ischemia (dogs, pigs)
ROlHL-20630-03 Development of a pulsed Doppler velocity
detector (human, animals)
ROlHL-20648-01
ROlHL-20782-01
(rats, dogs)
ROlHL-20803-02
lambs, cats)
ROlHL-20827-02
circulation (dogs)
ROlHL-2082902 Fluid mechanics of heart valve
prostheses (dogs, human)
ROlHL-20895-03 Cineangiographic studies of
cardiovascular system
' ROlHL-20895-03 0001 Cineangiographic studies of
cardiovascular system - Videodensitometry and valvular
regurgitation (human, dogs)
' ROlHL-20895-03 0002 Cineangiographic studies of
cardiovascular system - Coronary disease-Regional
myocardial blood flow (human, dog)
Physical factors and coronary flow (dogs)
Coronary flow regulation by adenosine
Infra-aortic balloon pumping (dogs,
Effects of hypertrophy on the coronary
ROlHL-20895-03 0003
cardiovascular system
(human)
ROlHL-20895-03 0004
cardiovascular system
Cineangiographic studies of
Densitometry in coronary stenosis
Cineangiographic studies of
Cineangiography-Caronaiy lesions
and ventricular function (human)
ROlHL-20895-03 0005 Cineangiographic studies of
cardiovascular system - Computerized axial tomography-
Cardiac wall motion and infarction (dogs)
ROlHL-2089503 0006 Cineangiographic studies of
cardiovascular system - Cardiomyopathy-Hemodynamic.
radiologic, morphologic abnormalities (dog. rabbit)
ROlHL-20895-03 0008 Cineangiographic studies of
cardiovascular system - Intercoronary anastomotic
circulation-Stenosis and occlusion (dogs)
ROlHL-2089503 0011 Cineangiographic studies of
cardiovascular system - Ventricular hypertrophy and
preoutflow contraction (human, dogs)
P50HL-21006-02 0005 Specialized center of research in
arteriosclerosis - Regional myocardial perfusion in patient
with coronaiy artery disease (also dogs)
(contd)
'Excludes routine methodok>(y OR covers only general projects which preclude indexing at the specific level.
"Orwflted significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
HIA
24)
HEA
R23Hl'2l042 01 CaidiopulmoniKY lallexes and Ihtit
(natomical basis (do|s)
R01HL21IS8 02 Cardiac receptors with vagal C llbar
alfarents (cats)
ROIHL 71209 02 Alterations of metabolism in ischemic
myocardium (swine)
ROIHl 21293 02 Randomiied study ol coronary bypass
surgery (human)
R23HL 21298 02 Coronary vasomotion (dogs, pigs)
R23HL 21327 02 Molecular mechanisms of chemical
myocardiopathies (rats)
R23HI 2139301 Cardiac adaptation to aging and stress
(rats)
R23HI 21434 02 Intrinsic control ol coronary blood tlow by
chemicals (guinea pigs)
ROIHL2I49802 Pathophysiology ot edema (rats, cats)
R01HL21657 01 Regional non ischemic myocardial
hypoxia (dogs)
ROIHI 21684 02 0002 Radionuclide infarct siting and
therapy evaluation Evaluating myocardial imaging agents
in global and regional ischemia (rabbits)
ROIHL 21786 01 Long term effects of myocardial
protection (dogs, rats)
RO1HL2187201
heart (dogs)
ROlHL-21893-01
Myocardial perfusion in the hypertrophied
Blood volume distribution in hypertension
(human)
R23HL 22004 01
Imaging and ECG studies in acute and
chronic IHD (human)
Ventricular dysfunction and cardiac
Cardiac adaptation to physical training
ROlHL-2215202
surgery (dogs)
ROlHL-22154 01
(dog)
ROlHL-2221501 Effects of exercise-training in ischemic
heart disease (human)
R23HL'22245'02 Functional characteristics of atrial
receptors (rats)
ROIHL'2227401 Quantitating in series effects in cardiac
arrhythmias (dogs)
ROlHL-2228101 Microprobe analysis and metabolite
levels of ischemic mycardium (dogs)
ROIHL'22315'01 Intraoperative cardiac oxygen supply-
demand (dogs, rabbits, rats)
ROlHL-22326-01 Noninvasive measurement of cardiac
output (dogs)
ROlHL-22470-01 Liposome myocardial uptake in infarct
and ischemia (dogs, rats, mice)
ROlHL-22527-01 Prostacyclin-thromboxanes in the
cardiovascular system (human, rabbits)
Reflex control of the circulation in heart
Cardiovascular effects from visceral
** ROlHL-2259401
failure (dogs)
R23HL-22669-01
afferents (dogs)
ROlHL-22759-01 Regional myocardial blood flow during
hypothermia (dogs)
R23ffL-22787'01 Cardiac volume by biplane
echocardiography (human)
** ROlHL-22801-01 Analysis of coronary artery behavior
(dogs)
ROlHL-228 15-01 Regional myocardial function after
revascularization (dogs)
ROlHL-22828-''' Adenosine and catecholamine interaction
in the heart (rats)
** ROlHL-22917-01 Microvascular pressures in the intact
beating heart (rabbits)
** ROlHL-22946-01 Prostaglandins, platelet aggregation and
vasoactivity (human, rats, rabbits)
ROlHL-22952-01 Validation of quantitative coronary
arteriography (dogs)
** R01HL-23171-01 Coronary collateral circulation in
myocardial ischemia (dog, pig. rat, human)
R01HL-23206-01 Repetitive exercise and cardiac
enlargement (dogs)
** ROlHL-23653-01 Protection of the ischemic myocardium
(dogs)
** ROlHL-23982-01 Control of coronary flow by carbon
dioxide tension (dogs)
NOlHV-62960-00 Techniques to protect ischemic
myocardium and minimize infant size (human)
HEART CONDUCTION SYSTEM
SEE HEART, CONDUCTION SYSTEM
HEART CONGENITAL ABNORMALITIES
SEE CONGENITAL ABNORMALITIES, HEART DEFECTS
HEART CONTRACTION
SEE HEART FUNCTION. HEART CONTRACTION
HEART DEFECTS
SEE CONGENITAL ABNORMALITIES. HEART DEFECTS
HEART DIMENSIONS AND WEIGHT
SEE ALSO HEART DISORDERS, HEART ENURGEMENT
SEE ALSO HEART FUNCTION, INTRACARDIAC VOLUME
ROlHL-01015-27 Hypertension and left ventricular
hypertrophy (dogs)
POlHL-04664-18 0003 Cardiovascular and lung dynamics
- X-ray projection image videometry (human, dogs)
P01HL-04e64-18 0004 Cardiovascular and lung dynamics
- X-ray cross section imaging of the circulation (dogs)
POlHL-06285-18 0178 Cardiovascular-respiratory
physiology and biochemistry - Biochemical regulation of
hypertrophy (rats, rabbits)
POIHL 06308 IH 0042 Mechanisms and therapy ol
circulatory disease Echocardiographic assessment ot
arrhythmias Myocardial tissue type (human, dogs)
POIHI 06308 18 0043 Mechanisms and therapy ol
circulatory disease Exercise and echocardiographic
examining techniques (human)
POIHL 06312 1/ 0018 Surgical cardiology Cardiac
tiansplant.ilion growth (calves)
POIHL 06835 17 0038 Cardiovascular disease Effect of
chronic administration ol angiotensin antagonist (rats)
POIHL 07293 17 Noninvasive cardiovascular
measurements
POIHL 07293 17 0041 Noninvasive cardiovascular
measurements Ventricular volumes and dimensions
(human)
POIHL'07293'17 0043 Non-invasive cardiovascular
measurements ECHO Doppler instrumentation for cardiac
measurements (human)
P01HL07293 17 0045 Non invasive cardiovascular
measurements Cardiac scanner transducer position
locating systems (human)
P01HL07293 17 0046 Non invasive cardiovascular
measurements Cardiac scanner signal processors
P01HL07293 17 0047 Non-invasive cardiovascular
measurements Cardiac scanner system software
POlHL-0729317 0049 Non-invasive cardiovascular
measurements Cardiac scanner engineering evaluation
and error analysis
POlHL-07293-17 0050 Non invasive cardiovascular
measurements Cardiac dimensions measurements
engineering evaluation and error analysis
POlHL-07293-17 0051 Non-invasive cardiovascular
measurements - Physiologic evaluation of duplex scanner
(dogs)
POlHL-07293 17 0052 Non-invasive cardiovascular
measurements Clinical evaluation of the duplex scanner
(human)
POlHL-07293-17 0053 Non-invasive cardiovascular
measurements Clinical evaluation of cardiac dimensions
using the duplex scanner (human)
POlHL-10539-12 0069 Pathophysiology of circulation -
Ventricular compliance and mechanics in intact ventricles
(human)
POlHL-11310-12 0056 Mechanisms of cardiovascular
disease - Cardiac output response to blood pressure
reduction in infants (human)
POlHL-1 13 10-12 0060 Mechanisms of cardiovascular
disease - Effect of left atrium on the circulation -Simulation
POlHL-1 13 10-12 0061 Mechanisms of cardiovascular
disease - Computer simulation of transposition of great
arteries in infants
POlHL-11310-12 0080 Mechanisms of cardiovascular
disease - Metabolism of the hypertrophied myocardium
(human)
POlHL-11414-11 0034 Thrombosis and atherosclerosis
program - Servo simulation-Experimental myocardial
infarction (dogs)
POlHL-12373-10 0001 Cardiopulmonary physiology and
pathophysiology - Mechanics of myocardial contraction
(dogs, rats, swine)
POIHL 12373-10 0002 Cardiopulmonary physiology and
pathophysiology - Determinants of performance of the
whole heart (dogs)
POlHL-123 73-10 0003 Cardiopulmonary physiology and
pathophysiology - Myocardial function in man
ROlHL-12494-10 Continuum mechanics in biophysics
(human, animals)
ROlHL-12997-07 Myocardial defects induced by potassium
depletion (human, rats, cats)
P50HL-142 14-07 0030 Newborn lung center for hyaline
membrane disease - Effects of ductal patency-Impedance
cardiography and echocardiography (human)
ROlHL-14545-06 Mechanics of compensatory ventricular
hypertrophy (dogs)
ROlHL-154 16-06 Cardiovascular control in normal and
disease states (dogs, baboons)
P01HL-15835-06 0023 Study of muscles related to heart
disease - Cellular basis of the Frank-Starling curve (frogs,
rats)
ROlHL-15837-06 Renin and cardiac hypertrophy in
hypertension (rats)
P50HL-17646-04 0002 Study of ischemic heart disease -
Core data management
' P50HL-1 7646-04 0010 Study of ischemic heart disease -
Compliance in ischemic myocardium-Altered cardiac
performance (human, dogs)
P50HL-17651-04 0032 Ischemic heart disease specialized
center of research - Cardiovascular surgery core (human,
dogs)
P50HL-17655-04 0001 Study of ischemic heart disease -
Intravenous nitroglycerin-Ventrlcular function and infarct
size (human, dog)
P50HL-I7667-04 0030 Study of ischemic heart disease -
Computerized clinical data acquisition and processing
P50HL-17e69-04 0006 Ischemic heart disease center
(SCOR) - Studies of hypoxic, acidotic and ischemic cardiac
muscle (dogs)
P50HL-17669-04 0007 Ischemic heart disease center
(SCOR) - Relationship between myocardial depression and
compliance (dogs, cats)
P50HI 1 7669 04 0008 hchemic heart diittt* center
(SCOR) Segmental ventricular dyilunclion during ilrtii
induced ischemia (dog. human)
P50HI 17670 04 0009 Study ol ischemic heart diteaM
Surgical treatment of locili/td left vtntriculir dyitynergy
(human, dogs)
P50HL 17670 04 0014 Study ol ischemic heart diieaie
Real time ultrasound imaging in ischemic heart disaate
(human, dog)
P50HL 17682 04 0003 Study ol ischemic heart diseate
Effects ot myocardial revascularization in man
P50HL 17682 04 0011 Study of ischemic heart disease
Nuclear medicine core unit (human, dogs, rabbits, mice)
P50HL 17682 04 0012 Study of ischemic heart disease
Pathology core laboratory (human)
P50HL 17682 04 0014 Study of ischemic heart disease
Myocardial ischemia Instrumentation and technique (dogs,
baboons)
P50HL 17682 04 0015 Study of Ischemic heart diuiu -
Acute myocardial ischemia and infarction and their
reversibility (dogs, baboons)
ROIHL 18639 03 Human anatomy lor cardiac prostheses
(human)
POIHL 18646 03 0008 Studies basic to heart
transplantation Immunophysiology and early detection of
rejection (dogs)
ROIHL 18749-03
heart (dogs)
ROIHL 19246-03
Ventricular mechanics in the overloaded
Regression ol cardiac hypertrophy
Myocardial and renal (human)
ROIHL 19257 03 Cardiovascular adjustment to behavioral
stress (dog)
ROlHL-19425 03 Cardiac function in hypertrophy (dog)
** ROlHL-19451-03 0001 Functional characteristics of the
left heart - Ventricular performance using epicardial
radiopaque markers (human)
ROIHL 19451 03 0003 Functional characteristics of the
left heart - Left ventricular segmental contraction (human,
dogs)
** ROlHL-19486-03 Dipole moment measurement of cardiac
mass (rabbits, pigs)
M POlHL-20552-02 The development and regression of
cardiac hypertrophy
POlHL-20552-02 0002 The development and regression of
cardiac hypertrophy - Effect of treatment on the
hypertrophied left ventricle (rats)
POlHL-20552-02 0004 The development and regression of
cardiac hypertrophy - Ventricular function in experimentally
induced hypertrophy (hogs, sheep, baboons)
** ROlHL-20883-02 Fiber geometry in hypertrophy and
cardiomyopathy (human)
ROlHL-21684-02 0004 Radionuclide infarct sizing and
therapy evaluation - Image analysis-Kinetics of infarction.
ventricular function (human, animal)
ROlHL-21872-01 Myocardial perfusion in the hypertrophied
heart (dogs)
ROlHL-22859-01 Effect of carbon monoxide on the
developing heart (rats)
ROlHL-23171-01 Coronary collateral circulation In
myocardial ischemia (dog. pig. rat. human)
NOlHV-62960-00 Techniques to protect ischemic
myocardium and minimize infant size (human)
HEART DISEASE EDUCATION
SEE EDUCATION. HEALTH EDUCATION, CARDIOVASCULAR
DISEASE EDUCATION
HEART DISORDERS
SEE ALSO CARDIOVASCULAR DISORDERS (GENERAL)
SEE ALSO CONGENITAL ABNORMALITIES, HEART DEFECTS
SEE ALSO DISEASES, COMPLICATIONS. POSTPERICARDIOTOMY
SYNDROME
SEE ALSO RESPIRATORY CIRCUUTORY DISORDERS.
PULMONARY HEART DISEASE
** ROlHL-01486-23 Quantitative study of T-wave mechanisms
(human, rabbits, dogs, chickens)
POlHL-04664-18 0008 Cardiovascular and lung dynamics
- Micrographic video imaging technique
" ROlHL-05694-20
disease (human)
M POlHL-06285-18
Functional pathology of cardiovascular
Cardiovascular-respiratory physiology and
biochemistry
M POlHL-06312-17 Surgical cardiology
** POlHL-06312-17 0046 Surgical cardiology - The
relationship of prostaglandins to heart disease
POlHL-06312-17 0050 Surgical cardiology - Prevention of
pericardial and pleural adhesions by silicone oil (dogs)
M POlHL-06370-17 Cardiopulmonary and renal pathology
research center
ROlHL-07047-16 Comparative study of cardiac conduction
system (human, birds, mammals)
M POlHL-08805-15 Regulation of ventilation and pulmonary
circulation
ROlHL-09711-13 Instantaneous blood flow in ascending
aorta (human, dogs)
ROlHL-09831-12 Effect of resistivity variations on
electrocardiogram (human)
ROlHL-09914-13 The myocardium in diabetes mellitus
(dogs, monkeys)
" POlHL-1034213 0008 The integrated function of
respiration and circulation - Respiratory mechanics and the
circulation (human, dogs)
M POlHL-10539-12 Pathophysiology of circulation
(contd)
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
HEA
POlHL-11307-12 Biophysical studies in pediatric
cardiology
POlHL-11307'12 0002 Biophysical studies in pediatric
cardiology - Cardiac extracellular electrophysiology (human,
dog, chimpanzee)
PCIHL11310-12 Mechanisms of cardiovascular disease
POlHL-11310-12 0081 Mechanisms of cardiovascular
disease - Analysis of regional left ventricular function
(human)
POlHL-11351-12 Cellular and molecular mechanisms of
myocardial function
ROlHL-1 1906-11 Comparative study of heart function
(cats, rats, hedgehogs, squirrels)
ROlHL-1 1907-08 Mechanisms of physiological responses
to exercise (human, dogs)
ROlHL-1 1919-08 Pulmonary circulation in surgical heart
disease (human, dogs)
POlHL-12373-10 Cardiopulmonary physiology and
pathophysiology
P01HL12373-10 0001 Cardiopulmonary physiology and
pathophysiology - Mechanics of myocardial contraction
(dogs, rats, swine)
POlHL-12373-10 OOOS Cardiopulmonary physiology and
pathophysiology - Characterization of fetal and neonatal
myocardium (human, cats)
P01HL-12738-10 Physiologic pharmacology and its clinical
applications
POIHL-12738-10 0065 Physiologic pharmacology and its
clinical applications - Psychotheropeutic drugs and
cardiovascular system (human, rats)
' POlHL'13108-09 0001 Clinical heart transplantation -
Therapy and prognosis (human)
POlHL-13330-08 Mechanical circulatory support
POlHL-13330-08 0031 Mechanical circulatory support -
Hemodynamics of cardiac prosthesis
' POlHL-13330-08 0034 Mechanical circulatory support ■ In
vivo test and evaluation of left ventricular bypass pumps
(human, cattle)
POlHL-13480-09 Cardiac electrophysiology
' ROlHL-13639-07 factors altering the course of myocardial
dysfunction (cats)
PO1HL1373707 Assisted circulation
POlHL-1373808 Cardiac assist devices and artificial
hearts
POlHL-14388-07 Regulation of the circulation in
pathological states
' P01H114388-07 0164 Regulation of the circulation in
pathological states - Hyperkinetic heart syndrome (human)
R01HL15016-07 New concepts in cardiac ultrasound
technology (human)
P50HL-15103-07 0001 A/S SCOR-Early natural history of
arteriosclerosis ■ Clinical research-Bogalusa heart study
(children)
* ROlHL-1561404 Heredity and oxygen -Effects on health of
heart-lungs (South America)
' ROlHL-15764-05 C-AMP dependent protein kinase in
cardiac contraction (dogs)
POlHL-15835-06 0011 Study of muscles related to heart
disease - Energetics and mechanism of muscle contraction
(frogs, rabbits)
* ROlHL-15840-02 Sugar-induced heart lesions and vitamin
K deficiency (birds, mammals subhuman)
ROIHL- 166 78-03 Fluorescent probe studies of heart
muscle proteins (rabbit, dog)
I P60HL-1 7269-04 National heart and blood vessel research
and demonstration center
* P60HL- 17269-04 0033 National heart and blood vessel
research and demonstration center - Autoallergic response
in cardiomyopathy, atherosclerosis, rheumatic heart disease
* ROlHL-17404-05 Immunologic mechanisms in heart
disease (mice)
* ROIHL- 18338-04 Computer feedback study of cardiac
muscle mechanics (rats)
* ROlHL-18398-04 Mechanisms of delayed and asymetric
ventricular conduction (human, dogs)
* ROlHL-18593-03
(human, pig)
* ROIHL- 1939 1-03
filling (dogs)
ROlHL-19460-03 Mechanics of the papillary muscle and
the left ventricle (cats, rabbits)
POlHL-19737-02 0009 Cellular and molecular aspects of
respiratory physiology - Regulation of tissue oxygen tension
and body carbon monoxide stores (human, dogs)
ROlHL-19768-02 Recording and analysis of low levels
cardiac signals (human, dogs)
ROlHL-19898-03 Oesferrioxamine therapy in thalassemia
(dogs, rats, children)
II POlHL-2059202 Cell biology of cardiac and skeletal
muscle
ROlHL-20787-02 Thromboxanes and prostaglandins-
Biochemical pharmacology (rabbits, human)
•* ROlHL-22080-01 Phosphorus NMR studies on carjiac
tissue (rats, rabbits)
ROlHL-22265-02 Isozymes of heart glutamate aspartate
transaminase (swine, ducks)
R23HL-22575-01 Factors modifying cardiac digoxin effects
and content (dogs, cats)
ROlHL-22604-01 Non-invasive system for arteriosclerosis
studies (human)
•• ROlHL-23994-01 Biochemical properties of human cardiac
myotin
Characterization of heart valve collagen
Dynamic determinants of left ventricular
242
** NOlHV-62969-03 Cardiology patient simulator evaluation
HEART DISORDERS, ANEURYSMS
POlHL-1438807 0221 Regulation of the circulation in
pathological states - Experimental myocardial infarction
(dogs)
R01HL-146S1-05 Mechanical behavior of left ventricle
(dogs, rats)
P50HL- 17667-04 0001 Study of ischemic heart disease -
Natural history of ischemic heart disease (human)
ROlHL-20597-02 Electrophysiologic correlates of
myocardial ischemia (human, dogs, rabbits)
R23HL-22004-01 Imaging and ECG studies in acute and
chronic IHD (human)
HEART DISORDERS, ARRHYTHMIA
SEE ALSO CARDIOVASCULAR AGENTS, ANTIARRHYTHMIC
AGENTS
SEE ALSO CONGENITAL ABNORMALITIES, HEART DEFECTS,
WOLFF-PARKINSON-WHITE SYNDROME
SEE ALSO HEART DISORDERS, SUDDEN DEATH
SEE ALSO HEART RESUSCITATION, ELECTRIC COUNTERSHOCK
ROlHL-01803-23 0021 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Induction of IgE antibodies to antigen
from tobacco and cigarette smoke (rabbits)
** ROlHL-01803-23 0022 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Cardiac and pulmonary anaphylaxis
induced by tobacco glycoprotein (rabbits)
M POlHL-0630818 Mechanisms and therapy of circulatory
disease
** POlHL-06308-18 0012 Mechanisms and therapy of
circulatory disease - Echocardiographic evaluation of
hemodynamics of arrhythmia (human)
** POlHL-06308-18 0025 Mechanisms and therapy of
circulatory disease - Subcellular calcium pools in the
genesis of arrhythmias (dogs)
** POlHL-06308-18 0039 Mechanisms and therapy of
circulatory disease - ANS in regulation of electrophysiology-
Role of cyclic nulceotides (animals)
** POlHL-06308-18 0040 Mechanisms and therapy of
circulatory disease - Metabolism and fatty acid utilization-
Heart electrical stability (rats, dogs)
** POlHL-06308-18 0042 Mechanisms and therapy of
circulatory disease - Echocardiographic assessment of
arrhythmias -Myocardial tissue type (human, dogs)
** POlHL-063 1217 0025 Surgical cardiology - Effect of
denervation on arrhythmias and function with coronary
occlusion (dogs)
ROlHL-07047-16 Comparative study of cardiac conduction
system (human, birds, mammals)
** ROlHL-07139-17 Cardiodynamics and metabolism of
congestive failure (human, dogs)
** ROlHL-08508-15 Cardiac conductivity and automaticity
(human, dogs, rabbits)
POlHL-08682-15 Regulation of the cardiovascular system
POlHL-08682-15 0015 Regulation of the cardiovascular
system - Projection of autonomic nerves onto the heart
(dog)
POlHL-08682-15 0016 Regulation of the cardiovascular
system - Shitting cardiac pacemakers and AV nodal
activation (dog)
POlHL-08682-15 0017 Regulation of the cardiovascular
system ■ Neurally induced cardiac dysrhythmias (dog)
ROlHL-093 15-15 Coronary insufficiency and myocardial
revascularization (human, dogs)
ROlHL-099 14-13 The myocardium in diabetes mellitus
(dogs, monkeys)
POlHL-10436-13 0002 A multidisciplinary study of
congenital heart disease - Myocardial performance,
metabolism and ultrastructure (human, cats, rats)
POlHL-10539-12 0064 Pathophysiology of circulation -
Exercise physiology and pathophysiology (human)
ROlHL-10951-11 Neural control of the heart (dogs, rats)
POlHL-1 1307-12 0002 Biophysical studies in pediatric
cardiology - Cardiac extracellular electrophysiology (human,
dog, chimpanzee)
POlHL-1 13 10-12 Mechanisms of cardiovascular disease
POlHL-1 13 10-12 0077 Mechanisms of cardiovascular
disease - Abnormalities of rhythm and conduction following
heart surgery (human)
POlHL-1 13 10-12 0092 Mechanisms of cardiovascular
disease - Exercise electrophysiology (human)
ROlHL-126 11-10 Basic and clinical studies of the ST-T
deflection (human, dogs)
POlHL-12738-10 0001 Physiologic pharmacology and its
clinical applications - Clinical pharmacology of cardioactive
HEA
M
M
drugs (human)
POlHL-12738-10 0035
clinical applications -
Physiologic pharmacology and its
Function and dysfunction of the
sinoatrial node (human)
POlHL-12738-10 0042 Physiologic pharmacology and its
clinical applications - Centrogenic cardiac arrhythmias
(cats)
POlHL-12738-10 0076 Physiologic pharmacology and its
clinical applications - Pediatric cardiac electrophysiology
and pharmacology (human, dogs)
POlHL-12738-10 0080 Physiologic pharmacology and its
clinical applications - Electrophysiology of cardiac muscle
in the mitral valve (monkeys)
POlHL-12738-10 0081 Physiologic pharmacology and its
clinical applications - Ultra structural and electrophysiologic
alteration of myocardium (human, dogs)
Physiologic pharmacology and its
Blood superfused cardiac fibers
Physiologic pharmacology and its
Physiology and pharmacology of
Physiologic pharmacology and its
Cardiac electrical activity (human.
Physiologic pharmacology and its
Coronary occlusions and arrhythmias
POlHL-12738-10 0107
clinical applications -
(dogs)
P01HL12738-1C 0110
clinical applications
arrhythmias (dogs)
POlHL-12738-10 0127
clinical applications -
animals)
POlHL-12738-10 0132
clinical applications
(dogs)
ROIHL- 13036-08 Coronary thrombosis-Effects on
myocardium and in vivo detection (dogs, monkeys)
P01HL-13I08-09 Clinical heart transplantation
POlHL-13108-09 0008 Clinical heart transplantation -
Physiology and pharmacology of the transplanted human
heart
POlHL-13108-09 0017 Clinical heart transplantation -
Electrophysiology of the transplanted denervated human
heart
POlHL-1 3 108-09 0019 Clinical heart transplantation -
Effect of autonomic nervous system on arrhythmias
(human)
' R01HL13375-09 Cellular potential changes causing
cardiac arrhythmias (dogs)
POIHL- 13480-09 0026 Cardiac electrophysiology - Neural
influences on cardiac electrophysiology and contraction
(dog, cat)
■ POIHL- 13480-09 0028 Cardiac electrophysiology - Stress
electrocardiography (human, dogs)
' POIHL- 13480-09 0042 Cardiac electrophysiology •
Computer modeling of arrhythmias
' ROlHL-13623-08 Atrial receptors (dogs)
' ROlHL-13666-06 Pharmacology of genesis of cardiac
rhythmicity (rats, cats)
' ROlHL-13920-07 Expanding the role of surgery of atrial
dysrhythmias (dogs)
ROlHL-14614-07 Voltage control of contraction in heart
(sheep)
ROlHL-14688-05 Myocardial assessment by inverse
electrocardiography (monkey)
' ROlHL-14832-06 Myocardial cells -Autonomic and rhythmic
mechanisms (chick embryo, rats)
• ROlHL-14899-07 Mechanism and prevention of cardiac
arrhythmias (dogs)
• ROlHL-15190-07 Physiological basis of arrhythmias and
their therapy (human)
P01HL-15I94-07 Pathophysiology of cardiopulmonary
dysfunction
• POlHL-15194-07 0004 Pathophysiology of
cardiopulmonary dysfunction ■ Specialized electrophysiology
fibers-Electrogenic basis of glycosides (mammals)
ROlHL-15740-06
(rats)
ROIHL- 15790-06
attacks (human)
ROlHL-16052-05
In vitro studies on heart cell function
Follow-up study of acute coronary heart
Cardiac gtycosides-Mechanism of
inotropic action (dogs)
Mechanisms of cardiac autorhythmicity
Innervation of coronary arteries and heart
ROlHL-16135-05
(dogs, bats)
ROlHL-16657-06
(rats)
ROlHL-17367-05 Functional sympathetic development in
neonatal hearts (dogs, human)
R01HL174510S Digitalis effects on cardiac automaticity
mechanisms
P50HL-17646-04 0001 Study of ischemic heart disease -
Core clinical investigation unit
P50HL-17646-04 0015 Study of ischemic heart disease -
Protecting ischemic myocardium in patients with evolving
myocardial infarction
P50HL-17646-04 0016 Study of ischemic heart disease -
Humoral factors in ischemic heart rhythm, mechanical
performance (dog, rabbit)
P50HL-17646-04 0017 Study of ischemic heart disease -
Dysrhythmia associated with acute myocardial infarction
(human, cat)
P50HL-1764804 0014 Study of ischemic heart disease -
Antidysrhythmic drugs and mammalian cardiac Purkinje
fibers (sheep, dog)
P50HL-17648-04 0033 Study of ischemic heart disease -
Data management-Electrocardiographic analysis system
P50HL-17651-04 0022 Ischemic heart disease specialized
center of research - Electrophysiology-Mechanism and
pharmacology of arrhythmias (human, dog)
P50HL-17651-04 0023 Ischemic heart disease specialized
center of research - Development of multipurpose catheter
for monitoring and electronic pacing
P50HL176S1-04 0043 Ischemic heart disease specialized
center of research - Gradual reperfusion following acute
coronary occlusion (dog)
P50HL-17651-04 0046 Ischemic heart disease specialized
center of research - Clinical core-Physiological
changes/biochemical effects of myocardial ischemia
' P50HL-1765I-04 0047 Ischemic heart disease specialized
center of research - Clinical core-Automated arrhythmia
monitoring system
P50HL17655-04 0004 Study of ischemic heart disease -
Coronary arteriography in survivors of acute myocardial
infarction (human)
(contd)
tMMa routine nwthodotogy OR covers only general projects which preclude indexing at the specific level.
' *0r!eiHi4 •i«ntficantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for Investigator's name and grant number.
HEA
HEA
PbOHl 1 766!) 04 0001 Study ot tjchamic hitrt iiittm
Reduction at acute anteiioi myocaidial Infarction
Meclianical ciiculatory assist
PbOHL i;66b04 0002 Study ot isctiemic heart disease
Reducini acute anteiioi myocardial intarctlon Beta
adreneriic blockade (human)
PbOHl 1 ;66S 04 0003 Study ot iscliemic heart disease
Quantitation ol iniury Acute myocardial infarction
complicated by shock (human)
PSOHL W66S04 0030 Study of ischemic heart disease
Data managemenl
•* P50HI 17667 04 0018 Study ol ischemic heart disease
Arrhythmias in ischemic heart disease (human)
*• P50HL 17667 04 0029 Study ol ischemic heart disease
Computer diagnosis of cardiac arrhythmias after open
heart surgery (human)
P50HL 17667 04 0030 Study of ischemic heart disease
Computerised clinical data acquisition and processing
PSOHL 17667 04 0031 Study of ischemic heart disease
Pathophysiology in ischemic heart disease (dog. cat. rabbit,
monkey)
PSOHL 17667 04 0038 Study of ischemic heart disease -
Clinical core unit
** PSOHLl 767004 0008 Study of ischemic heart disease
Surgical treatment of cardiac rhythm disorders (human,
dogs)
PSOHL 17670-04 0011 Study of ischemic heart disease ■
Pharmacology of ischemic myocardium (dogs)
" P50HL1767004 0012 Study of ischemic heart disease
Epidemiology of sudden death (human)
P50HL1767004 0014 Study of ischemic heart disease
Real time ultrasound imaging in ischemic heart disease
(human, dog)
PSOHL 1767004 0016 Study of ischemic heart disease ■
Core pathology laboratory (human, dogs, monkeys)
** PSOHL 1768204 0001 Study of ischemic heart disease
Studies in acute and chronic ischemic heart disease
(human)
** ROIHL 1790704 Brain regulation of cardiac arrhythmia
(pigs. cats, rats)
ROIHL'1804004 Waveform dependency in defibrillation
(calves)
R01HL18185-04 Cardiac glycosides and diuretics-Role of
NaO pump (dogs)
** ROlHL-18398-04 Mechanisms of delayed and asymetric
ventricular conduction (human, dogs)
ROlHL-18631 03 Ultrastructural correlates of myocardial
ischemia (rats, swine)
R01HL-186S7-03 Pharmacologic studies on neurogenic
digitalis effects (human, cats, dogs)
** ROlHL-18769-04 Studies in survivors of lethal arrhythmias
(human)
** ROlHL-18776-04 Prevention of acute and fatal
cardiovascular disease (human)
ROlHL-18793-03 Clinical-pathologic studies of sudden
cardiac death (human)
** R01HL18794-04 Prospective studies of conduction disease
(human)
** ROlHL-18796-04 txperimental cardiac arrhythmias (dogs)
** ROIHL- 18800-04 Prospective study of resuscitated sudden
death victims (human)
** ROlHL-19045-03 Electrophysiology of cardiac automaticity
(human, dogs)
ROlHL-19072-03 Modification of tissue injury in
myocardial infarction (dogs, human)
** R01HL-1907603 Vagal control of heart rate-A biophysical
model (rabbits)
ROlHL-19216-03 Characterization of cardiac pacemaker
activity (cat. dog, rabbit)
M POlHL-19259-03 Digoxin-specific antibody in human
therapy
POlHL-19259-03 0001 Digoxin-specific antibody in human
therapy - Primary structure of monoclonal antibodies
(rabbits)
POlHL-19259-03 0004 Digoxin-specific antibody in human
therapy - Digitalis-specific antibodies pharmacological
studies (human, dogs, sheep)
** ROlHL-19343-03 Behavioral influences on cardiac
contractility (monkeys)
** ROlHL-19391-03 Dynamic determinants of left ventricular
filling (dogs)
** ROlHL-19398-03 Regional conduction abnormalities and
arrhythmias (dogs)
ROlHL-19451-03 0003 Functional characteristics of the
left heart - Left ventricular segmental contraction (human,
dogs)
Cardiac actions of digitalis (dogs, cats)
Cardiac correlates of behavioral stress in
R23HI 711 SI 02 Ischemic myocardium Diilivery uf bluod
flovn and diug% (dogs)
Perinatal cnidiac electrophysiology (dogs)
learned heart rale control (humnn)
Automaticity of AV node and its adjacent
Pharmacologic studies on the ischemic
Role of taurine in the heart (dogs, rats.
R01HL1948703
ROlHL-19680-01
animals (dog)
ROlHL-19782-02
heart (dogs)
ROlHL-20211-02
mice)
ROlHL-20328-01 Noninvasive assessment of autonomic
cardiac control (dogs)
ROlHL-20558-02 Cardiac electrophysiology -Effects of ions
and drugs
ROlHL-21038-01 Electrically induced cardiac EM-
histochemical changes (animals)
R01HL-210S2-01 Evaluation of a digitalis therapy advisor
ROlHL-21117 01 Altitude adaptation in chronic lung
disease (human)
R23Ht 21368 02
ROIHL 21426 02
ROIHL 21S/4 01
tissues (dogs)
ROIHL 2171001 Electrocardiographic methods ot
quantifying infaict si/e (human, dogs)
ROIHL 21817 01 Catecholamines, blood pressure and
circulation
R01HL-22I3S0I Control of calcium fluxes across cardiac
membranes (dogs, rabbits, guinea pigs)
ROIHL 222IS01 Effects of exercise training in ischemic
heart disease (human)
ROIHL 2223S01 Mechanism of cardiac pacemaking
(rabbits)
ROIHL 22274 01 Quantitating in series effects in cardiac
arrhythmias (dogs)
ROIHL 22418 01
function (cats)
ROIHL 2248401
excitation (dogs)
ROIHL 22S62 02 Mechanism of cardiac action potential
propagation (tunicates)
ROIHL 22862 01 CNS mediated effects of antiarrhythmic
drugs (dogs)
ROlHL-22982-01 Multicentet postcoronary risk
stratification program (human)
ROIHL 2307101
(dog, human)
ROlhL-23599 01
disorders (dogs)
ROlHL-23624 01
Neural control of cardio-resplratory
Neural control of cardiac conduction and
Electrophysiology of lethal arrhythmias
Mechanisms of ischemic rhythm
Effect of drugs on ischemic cardiac cells
(dogs, guinea pigs, pigs)
** ROIHL 2397001 Mechanisms and control of sudden
cardiac death (human, dog)
NOIHV 62960 00 Techniques to protect ischemic
myocardium and minimize infant size (human)
HEART DISORDERS, ARRHYTHMIA, ATRIAL
FIBRILLATION
POlHL-08682 15 0038 Regulation of the cardiovascular
system - Control of pulmonary circulation (dogs)
" POIHL 11310-12 0071 Mechanisms of cardiovascular
disease - Electrophysiological studies of atrial flutter
(human)
** POlHL-11310-12 0072 Mechanisms of cardiovascular
disease - Electrophysiological studies of atrial tachycardia
with block (human)
** POlHL-1 13 10-12 0073 Mechanisms of cardiovascular
disease - Electrophysiological study of atrial fibrillation
(human)
** POlHL-11310-12 0074 Mechanisms of cardiovascular
disease - Electrophysiological studies of paraxysmal atrial
tachycardia (human)
POlHL-11310-12 0075 Mechanisms of cardiovascular
disease - Bipolar atrial electrograms from Bachmann's
bundle (dogs)
** P01HL-13480 09 0032 Cardiac electrophysiology - Cardiac
activation sequence (dogs)
P50HL-17667-04 0029 Study of ischemic heart disease -
Computer diagnosis of cardiac arrhythmias after open
heart surgery (human)
** ROlHL-19398-03 Regional conduction abnormalities and
arrhythmias (dogs)
HEART DISORDERS, ARRHYTHMIA,
BRADYCARDIA
** R01HL04666-19 Artificially paced hearts -Technology,
physiology (human, dogs)
POlHL-06285-18 0180 Cardiovascular-respiratory
physiology and biochemistry - Vagal C-fibers and their
influence on visceral and somatic function (animals)
POlHL-07896-15 0014 Environmental biomedical research
program - Mechanisms of respiration and circulation
(human, dogs)
POIHL-07896'IS 0059 Environmental biomedical research
program - Hyperoxygenation at elevated atmospheric
pressure on myocardial blood flow (dogs)
POlHL-10436-13 0014 A multidiscipllnary study of
congenital heart disease - Cardiovascular pharmacology
(dog)
POlHL-12738-10 0035 Physiologic pharmacology and its
clinical applications - Function and dysfunction of the
sinoatrial node (human)
ROlHL-13454-08 Behavioral stress and cardiomyopathy
(monkeys, cats)
P50HL-142 14-07 0029 Newborn lung center for hyaline
membrane disease - The diving reflex-Perinatal asphyxia.
pulmonary ischemia and HMD (sheep)
POlHL-1438807 0184 Regulation of the circulation in
pathological states - Vestibular reflexes in control of
circulation (human)
POlHL-14388-07 0208
pathological states
Regulation of the circulation in
Baroreceptor reflex function in normal
and hypertensive man
ROlHL-15498-06 Effects of physical training on heart
(rats)
P50HL-17648-04 0016 Study of ischemic heart disease -
Intraventricular conduction-Effect of pacing on conduction
and automaticity
ROlHL-17903-03 Regional circulatory responses to hypoxia
(rats. cats, rabbits)
ROIMI I8/'J4 04 Pio\pectiv« Jiudiot of conduction diMiM
(humnn)
PSOHL 1918/02 0011 Pedinfrit pulmoniiry SCON Hyilini-
membrane di-.ease Itfoits of hypoxia and hypercapnia on
developinK neivou'. ^y<.lem (riionkry. huinun)
HEART DISORDERS, ARRHYTHMIA, HEART
BLOCK
ROIHL 07605 16 Congenital heart di-.ea'.e reuarch
program (human, dogs)
ROIHt 09/11 13 Instantaneous blood flow in ascending
aorta (human, dogs)
" POIHL 10436 13 0005 A mullidisciplinary study of
congenital heart disease Pulmonary physiology in
congenital heart disease (human)
** POIHL 11310 12 00/2 Mechanisms of cardiovascular
disease Electrophysiological studies of atrial tachycardia
with block (human)
** POIHL 11310 12 0079 Mechanisms of cardiovascular
disease Electrophysiological studies of complete heart
block (human)
POIHL 11310 12 008/ Mechanisms of cardiovascular
disease Electrophysiology and electropharmacology of the
heart (dogs)
POIHL 11310 12 0090 Mechanisms of cardiovascular
disease Clinicopathological cardiovascular correlation
(human, animals)
POIHL 11310 12 0093 Mechanisms of cardiovascular
disease - Multiple dipole electrocardiogram project (human.
dogs)
** POlHL-1 1310-12 9001 Mechanisms of cardiovascular
disease Core support-hospital beds
** P50HL-17648 04 0016 Study of ischemic heart disease
Intraventricular conduction -Effect of pacing on conduction
and automaticity
P50HL 17648 04 0018 Study of ischemic heart disease -
Myocardial damage-Infarction vectors recalled by
premature atrial stimulation
ROlHL-1884803 Etiology and development of congenital
heart disease (dogs, cats)
R01HL19451-03 0003 Functional characteristics of the
left heart - Left ventricular segmental contraction (human.
dogs)
ROlHL-20597-02 Electrophysiologic correlates of
myocardial ischemia (human, dogs, rabbits)
** R23HL-21292-01 Human ventricular activation Patterns
and mechanisms (human)
R01HL-22S46-02 Baroreceptor reflex mechanisms in man
HEART DISORDERS, ARRHYTHMIA, HEART
BLOCK, ATRIOVENTRICULAR
** P01HL12738 10 0136 Physiologic pharmacology and its
clinical applications -
PSOHL- 17648-04 0016 Study of ischemic heart disease -
Intraventricular conduction -Effect of pacing on conduction
and automaticity
ROlHL-18794-04 Prospective studies of conduction disease
(human)
HEART DISORDERS, ARRHYTHMIA, HEART
BLOCK, BUNDLE BRANCH
POlHL-12738-10 0127 Physiologic pharmacology and its
clinical applications - Cardiac electrical activity (human.
animals)
P50HL-17648-04 0016 Study of ischemic heart disease -
Intraventricular conduction -Effect of pacing on conduction
and automaticity
P50HL-17651-04 0022 Ischemic heart disease specialized
center of research - Electrophysiology-Mechanism and
pharmacology of arrhythmias (human, dog)
ROlHL-18538-03
function (dog)
ROlHL-18794-04
(human)
R01HL18800-04
death victims (human)
ROlHL-20238-02
(human)
ROlHL-21527-01
(human)
ROlHL-2307101
(dog. human)
The role of electrotonus in His-Purkinje
Prospective studies of conduction disease
Prospective study of resuscitated sudden
nan)
Prospective bundle branch block study
Prospective study of bundle branch block
Electrophysiology of lethal arrhythmias
HEART DISORDERS, ARRHYTHMIA, HEART
BLOCK, STOKES-ADAMS SYNDROME
ROlHL-18794-04 Prospective studies of conduction disease
(human)
*♦ R01HL-21S27-01 Prospective study of bundle branch block
(human)
HEART DISORDERS, ARRHYTHMIA, PREMATURE
VENTRICULAR CONTRACTIONS
** P01HL06308-18 0044 Mechanisms and therapy of
circulatory disease - Echocardiography to determine site of
ectopic impulse formation (human, dogs)
ROlHL-07776-15 Sudden death and cardiac arrhythmias
(human, dogs, cats)
** P01HL-10S39-12 0023 Pathophysiology of circulation -
The relaxation response and therapy of disease states
(human)
POlHL-11310-12 0075 Mechanisms of cardiovascular
disease - Bipolar atrial electrograms from Bachmann's
bundle (dogs)
(contd)
'Excludes routine methodokigy OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to alwve subject.
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
HEA
244
HEA
POlHL'l 1310-12 0078 Mechanisms of cardiovascular
disease - Ventricular arrhythmias in acute myocardial
infarction (dogs)
POIHL'11310 12 0079 Mechanisms of cardiovascular
disease - Electrophysiological studies of complete heart
block (human)
ROlHL-12611-10 Basic and clinical studies of the ST-T
deflection (human, dogs)
P01HL12738-10 0080 Physiologic pharmacology and its
clinical applications - Electrophysiology of cardiac muscle
in the mitral valve (monkeys)
** P01HL1273810 0127 Physiologic pharmacology and its
clinical applications - Cardiac electrical activity (human,
animals)
POlHL-13108-09 0017 Clinical heart transplantation -
Electrophysiology of the transplanted denervated human
heart
POlHL-13108-09 0019 Clinical heart transplantation -
Effect of autonomic nervous system on arrhythmias
(human)
ROlHL-15190-07 Physiological basis of arrhythmias and
their therapy (human)
R01HL-1607e'06 Electrophysiology of fibrillation and
defibrillation (human)
P50HL17646-04 0017 Study of ischemic heart disease ■
Dysrhythmia associated with acute myocardial infarction
(human, cat)
P50HL-1 7648-04 0033 Study of ischemic heart disease -
Data management -Electrocardiographic analysis system
P50HL- 17665-04 0018 Study of ischemic heart disease ■
Computer correlation of data -Patients with ischemic heart
disease
P50HL-1 7667-04 0018 Study of ischemic heart disease -
Arrhythmias in ischemic heart disease (human)
P50HL-1 7670-04 0012 Study of ischemic heart disease -
Epidemiology of sudden death (human)
'* ROlHL-18783-04 Detection and control of ventricular
premature beats (human)
K ROlHL-18808-04 Prediction and prevention of sudden
cardiac death
** R01HL1880804 0001 Prediction and prevention of
sudden cardiac death - Prognostic significance of
premature ventricular contractions (human)
R01HL18808-04 0003 Prediction and prevention of
sudden cardiac death - Technical support (computer)
ROlHL-19045-03 Electrophysiology of cardiac automaticity
(human, dogs)
ROlHL-19391-03
filling (dogs)
ROlHL-20238-02
(human)
ROlHL-21010-02
40,000 persons
R23HL-21347-02
tachycardia
ROlHL-21574-01
tissues (dogs)
ROlHL-21654-01 Autonomic determinants of arrhythmia
due to ischemia (cats)
ROlHL-21735-01 Electrophysiology after healed myocardial
infarction (cats)
ROlHL-22215-01 Effects of exercise-training in ischemic
heart disease (human)
ROlHL-23078-01 Psychosocial stress and sudden coronary
death (human)
ROlHL-23599-01 Mechanisms of ischemic rhythm
disorders (dogs)
HEART DISORDERS, ARRHYTHMIA,
TACHYCARDIA
** ROlHL-04666-19 Artificially paced hearts-Technology,
physiology (human, dogs)
** P01HL06308-18 0029 Mechanisms and therapy of
circulatory disease - Characterization of the patient with
recurrent ventricular arrhythmias
** POlHL-06308-18 0044 Mechanisms and therapy of
circulatory disease - Echocardiography to determine site of
ectopic impulse formation (human, dogs)
POlHL-08682-15 0017 Regulation of the cardiovascular
system - Neurally induced cardiac dysrhythmias (dog)
** POlHL-11310-12 0072 Mechanisms of cardiovascular
disease Electrophysiological studies of atrial tachycardia
with block (human)
" POlHL-11310-12 0074 Mechanisms of cardiovascular
disease • Electrophysiological studies of paraxysmal atrial
tachycardia (human)
P01HL11310-12 0075 Mechanisms of cardiovascular
disease - Bipolar atrial electrograms from Bachmann's
bundle (dogs)
** POlHL-11310-12 0090 Mechanisms of cardiovascular
disease - Clinicopathological cardiovascular correlation
(human, animals)
ROlHL-12415-10 Evaluation of left ventricular function
(dogs, rabbits)
P01HL12738-10 0035 Physiologic pharmacology and its
clinical applications - Function and dysfunction of the
sinoatrial node (human)
** POlHL-12738-10 0081 Physiologic pharmacology and its
clinical applications - Ultrastructural and electrophysiologic
alteration of myocardium (human, dogs)
ROlHL-13427-09 Neural control of blood volume (monkeys,
dogs)
Dynamic determinants of left ventricular
Prospective bundle branch block study
Glycemia, other traits and CV death in
Accessory pathways and supraventricular
Automaticity of AV node and Its adjacent
Myocardial perfusion in the hypertrophied
Electrophysiology of lethal arrhythmias
ROlHL-1392007 Expanding the role of surgery of atrial
dysrhythmias (dogs)
ROlHL-15190-07 Physiological basis of arrhythmias and
their therapy (human)
ROlHL'15416-06 Cardiovascular control in normal and
disease states (dogs, baboons)
** ROlHL-1607606 Electrophysiology of fibrillation and
defibrillation (human)
P50HL-17665-04 0018 Study of ischemic heart disease -
Computer correlation of data -Patients with ischemic heart
disease
P50HL-17667-04 0018 Study of ischemic heart disease -
Arrhythmias in ischemic heart disease (human)
P50HL-1 7667-04 0029 Study of ischemic heart disease -
Computer diagnosis of cardiac arrhythmias after open
heart surgery (human)
P50HL- 176 82-04 0001 Study of ischemic heart disease -
Studies in acute and chronic Ischemic heart disease
(human)
ROIHL 18468-03 The distribution of flow in the
myocardium (dog, pig)
ROlHL-18657-03 Pharmacologic studies on neurogenic
digitalis effects (human, cats, dogs)
ROlHL-18769-04 Studies in survivors of lethal arrhythmias
(human)
ROlHL-18794-04 Prospective studies of conduction disease
(human)
ROlHL-18808-04 0001 Prediction and prevention of
sudden cardiac death - Prognostic significance of
premature ventricular contractions (human)
** ROlHL-19398-03 Regional conduction abnormalities and
arrhythmias (dogs)
ROlHL-21010-02 Glycemia, other traits and CV death in
40,000 persons
** R23HL-21292-01 Human ventricular activation-Patterns
and mechanisms (human)
** R23HL-21347-02 Accessory pathways and supraventricular
tachycardia
ROlHL-21532-02 Cardiovascular homeostasis and learning
(frogs, rats, human)
ROlHL-21872-01
heart (dogs)
ROlHL-23071-01
(dog, human)
HEART DISORDERS, ARRHYTHMIA,
VENTRICULAR FIBRILLATION
ROlHL-05806-18 Analysis of antiarrhythmic agents (dogs.
rabbits)
** POlHL-06308-18 0010 Mechanisms and therapy of
circulatory disease - Ventricular arrhythmias during exercise
to CHD and myocardial ischemia (human)
** POlHL-06308-18 0011 Mechanisms and therapy of
circulatory disease - Blood flow and electrical dysfunction
in ventricular arrhythmia (human)
** POlHL-06308-18 0029 Mechanisms and therapy of
circulatory disease - Characterization of the patient with
recurrent ventricular arrhythmias
** POlHL-06308-18 0037 Mechanisms and therapy of
circulatory disease - Electrophysiology, blood flow, and ANS
in ventricular fibrillation (dogs)
** POlHL-06308-18 0038 Mechanisms and therapy of
circulatory disease - Electrophysiology of ventricuair
arrhythmias associated with ischemia (dogs)
** POlHL-06308-18 0044 Mechanisms and therapy of
circulatory disease - Echocardiography to determine site of
ectopic impulse formation (human, dogs)
** ROlHL-07776-15 Sudden death and cardiac arrhythmias
(human, dogs, cats)
** POlHL-11310-12 0078 Mechanisms of cardiovascular
disease - Ventricular arrhythmias in acute myocardial
infarction (dogs)
ROlHL-126 11-10 Basic and clinical studies of the ST-T
deflection (human, dogs)
ROlHL-127 15-10 Dynamic cardiovascular measurement
using ultrasound
** POIHL 12738-10 0081 Physiologic pharmacology and its
clinical applications - Ultrastructural and electrophysiologic
alteration of myocardium (human, dogs)
** P01HL12738-10 0117 Physiologic pharmacology and its
clinical applications - Ventricular arrhythmias in ischemic
heart disease (human)
** POlHL-12738-10 0122 Physiologic pharmacology and its
clinical applications - Coronary perfusion of beating and
fibrillating hearts (dogs)
** POlHL-12738-10 0132 Physiologic pharmacology and its
clinical applications - Coronary occlusions and arrhythmias
(dogs)
" POlHL-12738-10 0136
clinical applications
" POlHL-13480-09 0032 Cardiac electrophysiology - Cardiac
activation sequence (dogs)
** ROlHL-13974-07 Ventricular premature beats and sudden
coronary death (human)
ROlHL-15247-05 Extending the life of implanted
pacemakers (dogs, human)
" ROlHL-16076-06 Electrophysiology of fibrillation and
defibrillation (human)
ROlHL-16292-05 0002 Surgery and non-obstructive
coronary insufficiency - Effects of hypothermia during
cardiopulmonary bypass (dogs)
Surgery and non-obstructive
Cardiopulmonary resuscitation
Physiologic pharmacology and its
ROlHL-16292-05 0017
coronary insufficiency -
(human)
ROlHL-17367-05 Functional sympathetic development in
neonatal hearts (dogs, human)
P50HL- 17646-04 0017 Study of ischemic heart disease -
Dysrhythmia associated with acute myocardial infarction
(human, cat)
PSOHL-17655-04 0001 Study of ischemic heart disease -
Intravenous nitroglycerin-Ventricular function and infarct
size (human, dog)
Brain regulation of cardiac arrhythmia
Waveform dependency in defibrillation
Studies in survivors of lethal arrhythmias
ROlHL-17907-04
(pigs, cats, rats)
ROlHL-18040-04
(calves)
ROlHL-18769-04
(human)
R01HL18795-04 Ischemic arrhythmias-Effect of
autonomic tone (dogs, rats, guinea pigs)
ROlHL-18796-04 Experimental cardiac arrhythmias (dogs)
ROlHL-18798-04 0003 Nervous and ionic factors in
sudden cardiac death - Left stellectomy in the prevention
of sudden death (dogs)
ROlHL-18805-04 0004 Sudden cardiac death and the
onset of myocardial infarction - Sudden death survivors-
Clinical follow-up and therapy (human)
ROlHL-18805-04 0007 Sudden cardiac death and the
onset of myocardial infarction - Analysis of pathologic
factors involved in sudden death (human)
ROlHL-19782-02
heart (dogs)
ROlHL-20226-02
physiology (dogs)
ROlHL-20648-01
R23HL-2 1292-01
Pharmacologic studies on the ischemic
Cardiac bypass and coronary collateral
Electrophysiology of lethal arrhythmias
Physical factors and coronary flow (dogs)
Human ventricular activation -Patterns
and mechanisms (human)
** ROlHL-2 1554-01 Autonomic determinants of arrhythmia
due to ischemia (cats)
** ROlHL-21674-01 Development of automatic implanted
defibrillator (dogs, cattle)
** ROlHL-21735-01 Electrophysiology after healed myocardial
infarction (cats)
ROlHL-23071-01
(dog, human)
HEART DISORDERS, CARDIAC TAMPONADE
ROlHL-13623-08 Atrial receptors (dogs)
ROIHL- 16246-06 Immunologic studies in
postpericardiotomy syndrome (human)
HEART DISORDERS, CARDIOGENIC SHOCK
" P01HL-063I2-17 0052 Surgical cardiology - Assay of
metabolic variables of rat heart
POlHL-11310-12 0062 Mechanisms of cardiovascular
disease - Myocardial depressant factor in postoperative
cardiac dysfunction (human, dogs)
POlHL-12738-10 0071 Physiologic pharmacology and its
clinical applications - lABP patient management in
ventricular power failure (human)
POlHL-12738-10 0123 Physiologic pharmacology and its
clinical applications - Ventricular assistance and
preservation (human, dogs)
POlHL-13330-08 0034 Mechanical circulatory support - In
vivo test and evaluation of left ventricular bypass pumps
(human, cattle)
** POlHL-13737-07 0028 Assisted circulation - Clinical
studies of intraaortic balloon pumping
POlHL-13738-08 0001 Cardiac assist devices and
artificial hearts - Cardiac assist devices (human, sheep)
ROlHL-14644-05 Optimization diastolic augmentation and
systolic sink (dogs)
** R01HL-15607-06 Physiological control of splanchnic
circulation (dogs)
** ROlHL-15676-06 The role of occult myocardial failure in
human shock (human, dogs)
" ROlHL-16233-05 Molecular cardiology of MDP-induced left
ventricular failure (dogs)
P60HL-17269-04 0023 National heart and blood vessel
research and demonstration center - Cardiovascular
pharmacology-Ischemia, shock and heart failure (dog, cat,
rat)
** P60HL-1 7269-04 0029 National heart and blood vessel
research and demonstration center - Clinical application af|
circulatory assistance (human)
P50HL-17646-04 0015 Study of ischemic heart disease - |
Protecting ischemic myocardium in patients with evolving
myocardial infarction
PSOHL-1 7648-04 0011 Study of ischemic heart disease -
Surgical treatment for acute myocardial ischemia (human,
dogs)
" P50HL-17665-04 0003 Study of ischemic heart disease -
Quantitation of injury-Acute myocardial infarction
complicated by shock (human)
P50HL- 17665-04 0012 Study of ischemic heart disease -
Myocardial ischemia -Cardiovascular performance in the
conscious baboon and dog
P50HL- 17667-04 0038 Study of ischemic heart disease -
Clinical core unit
R01HL-18i90-03 Myocardial blood flow in acute
myocardial infarction (human, dogs)
ROlHL-18599-02 Cardiovascular pharmacology of
ionophores (dogs)
(contd)
'Excludes (Dutine methodology OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
HEA
245
HtA
M
Functional pathology of cardiovascular
** ROIHL 18/31 02 RES slimul>tin( mntriials m
a>p«rlmental shock (do|s)
ROIHL 19000 03 Irreversible myocmdial infury (rats)
PMHL 19153 02 0006 SCOR Pulmonary edemas Eilology.
pathogenesis PulmonaiY vascular abnormalities in human
lung diseases
ROIHI 20630 03 Development of a pulsed Doppler velocity
detector (human, animals)
HEART DISORDERS, CORONARY
SEE ALSO CARDIOVASCULAR AGENTS. VASOOIUTORS.
CORONARY
SEE ALSO HEART DISORDERS, SUDDEN DEATH
SEE ALSO HEART REVASCUURIZATION
SEE ALSO HOSPITALS. INTENSIVE CARE UNITS. CORONARY
R01HL01803 23 0005 Arteriosclerosis, glomerulonephritis,
rheumatic fever Immunologic and dietary synergy in the
pathogenesis of atherosclerosis (rabbits)
ROIHL 01979 22 Arteriosclerosis in zoo animals on
controlled diets (animals)
ROIHL 03341-22 Epidemiology of atherosclerosis in Evans
Co Georgia
** R01HL03429 18 Central nervous system and coronary
heart disease (human)
POlHL-04664'18 Cardiovascular and lung dynamics
POIHL-04664'18 0001 Cardiovascular and lung dynamics
X-ray proiection image videodensitometry (dogs)
P01HL-046e4 18 0003 Cardiovascular and lung dynamics
- X-ray projection image videometry (human, dogs)
POlHL-04664 18 0010 Cardiovascular and lung dynamics
■ Left ventricular dynamics (human)
P0IHL-04e64-18 0012 Cardiovascular and lung dynamics
- Quantitative single plane left ventricular angiography
(human)
' P01HL-04e64-18 0013 Cardiovascular and lung dynamics
- Ventricular function in coronary disease using NIG and
ventriculograms (human)
POlHL-04664-18 0015 Cardiovascular and lung dynamics
■ Computer system for the cardiovascular laboratory
R01HL04697-17 International heart disease epidemiology
(human)
R01HL05694-20
disease (human)
ROlHL-06222-18 Clinical and laboratory studies in lipid
metabolism (human, mammals, non-human)
POlHL-06296-18 0003 Cardiovascular and pulmonary
adaptation to stress - Human exercise studies (human,
dogs)
POlHL-06308-18 Mechanisms and therapy of circulatory
disease
POlHL-06308-18 0010 Mechanisms and therapy of
circulatory disease - Ventricular arrhythmias during exercise
to OHO and myocardial ischemia (human)
POlHL-06308-18 0011 Mechanisms and therapy of
circulatory disease - Blood flow and electrical dysfunction
in ventricular arrhythmia (human)
POlHL-06308-18 0038 Mechanisms and therapy of
circulatory disease - Electrophysiology of ventricuair
arrhythmias assoc>'.ed with ischemia (dogs)
POlHL-06308-18 0043 Mechanisms and therapy of
circulatory disease - Exercise and echocardiographic
examining techniques (human)
P01HL-063I2-17 0053 Surgical cardiology - Enzyme
pattern following cardiac surgery (human)
P01HL-06835I7 0063 Cardiovascular disease - Studies
on prostaglandins (human, rabbits)
POlHL-0683517 0064 Cardiovascular disease ■ Studies
in atherosclerosis (human, animals)
POlHL-07293-17 Non-invasive cardiovascular
measurements
POlHL-07293-17 0041 Non-invasive cardiovascular
measurements - Ventricular volumes and dimensions
(human)
POlHL-07293-17 0043 Non-invasive cardiovascular
measurements - ECHO-Doppler instrumentation for cardiac
measurements (human)
POlHL-07293-17 0052 Non-invasive cardiovascular
measurements - Clinical evaluation of the duplex scanner
(human)
POIHL-0729317 0053 Non-invasive cardiovascular
measurements - Clinical evaluation of cardiac dimensions
using the duplex scanner (human)
POlHL-07293-17 0058 Non-invasive cardiovascular
measurements - Peripheral duplex scanner physiologic
evaluation
POlHL-07293-17 0059 Non-invasive cardiovascular
measurements - Intracardiac blood flow measurement
(human)
ROlHL-08311-14
(dogs, turtles)
ROlHL-08888-12 Cooperative study of drugs and coronary
heart disease (men)
ROlHL-08892-10 Cooperative study of drugs and coronary
heart disease
POlHL-08974-14 Natural and experimental atherosclerosis
POlHL-08974-14 0005 Natural and experimental
atherosclerosis - Atherosclerosis, coronary heart disease
and sudden death (human)
P01HL08974-14 0028 Natural and experimental
atherosclerosis - Geographic pathology of atherosclerosis
and coronary heart disease (human)
ROlHL-09914-13 The myocardium in diabetes mellitus
(dogs, monkeys)
Effects of drugs upon myocardial hypoxia
ROIHL 103H4 13 Blood flow and nucleotide metabolism
(animals)
ROIHL 10445 09 Cooperative study of drugs and coronary
heart disease (men)
POIHL 10539 1? Pathophysiology of circulation
ROIHL 10/05 09 Cooperative study ol drugs and coronary
heart disease (men)
POIHL 11310 12 Mechanisms of cardiovascular disease
POIHL 11310 12 0081 Mechanisms of cardiovascular
disease Analysis of regional left ventricular function
(human)
POIHL 11310 12 0084 Mechanisms of cardiovascular
disease Evaluation of cardiac function in chronic renal
failure (human)
ROIHL 11372 08 Cooperative study of drugs and coronary
heart disease (men)
ROIHL 11876 11 Regional myocardial blood flow and
metabolism (dogs, swine)
POIHL 12373 10 0002 Cardiopulmonary physiology and
pathophysiology Determinants of performance of the
whole heart (dogs)
POIHL 12373 10 0003 Cardiopulmonary physiology and
pathophysiology Myocardial function in man
ROIHL 12711 09 Mathematical approach to cardiovascular
mechanics (human, animals)
P01HL12738 10 0001 Physiologic pharmacology and its
clinical applications - Clinical pharmacology of cardioactive
drugs (human)
POIHL 12738-10 0071 Physiologic pharmacology and its
clinical applications • lABP patient management in
ventricular power failure (human)
ROlHL-12766-09 Structure function relation of blood
vessels (rats, monkeys)
ROlHL-1277709 Mechanisms in cardiac performance
(dogs, human)
R01HL-13036-08 Coronary thrombosis-Effects on
myocardium and in vivo detection (dogs, monkeys)
P01HL-I3 108-09 Clinical heart transplantation
POlHL-13108-09 0014 Clinical heart transplantation -
Platelets and coagulation in accelerated graft coronary
atherosclerosis
POlHL-13108-09 0017 Clinical heart transplantation -
Electrophysiology of the transplanted denervated human
heart
POlHL-13108-09 0022 Clinical heart transplantation -
Studies on cardiac receptors (human)
ROlHL-13257-09 Inhalation anesthesia on myocardial
metabolism (dogs, swine, human)
P01HL-13330-08 0034 Mechanical circulatory support - In
vivo test and evaluation of left ventricular bypass pumps
(human, cattle)
POlHL-13480-09 0028 Cardiac electrophysiology - Stress
electrocardiography (human, dogs)
POlHL-13737-07 0028 Assisted circulation - Clinical
studies of intraaortic balloon pumping
POlHL-13737-07 0033 Assisted circulation - Autologous
bioprosthetic grafts for coronary artery bypass surgery
(human, dogs)
POlHL-13737-07 0038 Assisted circulation -
Distinguishing the ischemic ventricle from scarred ventricle
by balloon pumping
R01HL-I3974-07 Ventricular premature beats and sudden
coronary death (human)
P50HL-14138-05 0010 Center for research on
atherosclerosis - Diet and exercise as therapy in men with
premature atherosclerosis
P50HL-14230-07 0088 A/S SCOR -Lipids, atherosclerosis
and thrombosis - Coronary risk factors in school children -
The Muscatine study
P50HL-14230-07 0097 A/S SCOR Lipids, atherosclerosis
and thrombosis - Studies of circulating platelet aggregates
(human)
P50HL-14236-05 0002 Prevention of premature
arteriosclerosis - Myocardial blood flow in patients with
coronary artherosclerosis
ROlHL-14644-05 Optimization diastolic augmentation and
systolic sink (dogs)
R01HL14688-05 Myocardial assessment by inverse
electrocardiography (monkey)
ROlHL-15047-06 Digital computer analysis of the
electrocardiogram (human)
ROlHL-15190-07 Physiological basis of arrhythmias and
their therapy (human)
POlHL-151 94-07 Pathophysiology of cardiopulmonary
dysfunction
POlHL-15194-07 0001 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation, venous
drainage and collateral flow (human, dogs)
POlHL-1519407 0019 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation, bypass
grafts and diastolic driving pressure (human, dogs)
POlHL-15194-07 0020 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation in
arteriographically normal arteries (human)
ROlHL-15374-03 Cooperative study of drugs and coronary
heart disease (human)
ROlHL-155 12-06 Drug treatment of stenosing primate
atherosclerosis (rabbits, monkeys)
ROlHL-15614-04 Heredity and oxygen-Effects on health of
heart-lungs (South America)
ROlHL-15676-06 The role of occult myocardial failure in
human shock (human, dogs)
'Excludes routine methodokigy OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
PUIHl l()ll/05 000/ Ion movements and membrane*, in
cardiovascular control PhyMological and molerular
properties of lonophore*. (dog*.. rabbi(%)
ROIHI 16233 05 Molecular cardiology of MDP induced left
ventricular failure (dogs)
ROIHL 16292 05 Surgery and non-obslruclive coronary
insufficiency
ROIHL 16403 05 Prognostication by computer Analyzed
vectorcardiogram (human)
ROIHL 1643/ 05 Drug treatment of atherosclerosis
(rabbits, monkeys)
ROIHL 1648404 Radiographic ventriculometry (or coronary
heart disease (human)
ROIHL 16/6005 Dynamic control of coronary blood flow
(dogs)
ROIHL 1690804 Myocardial function, risk (actors and
future CHD (men)
ROIHL 1690904 Myocardial function, risk factors and
tuture CHD (men)
POIHL 16910-05 0002 Regulation of the peripheral
circulation Coronary circulation (dogs)
ROIHL 16952-05 Cardiovascular pathology (rats, rabbits)
ROIHL 17246 03 Oxygen uptake at one minute of exercise
(human)
P60HL-17269 04 National heart and blood vessel research
and demonstration center
P60HL 17269-04 0039 National heart and blood vessel
research and demonstration center - Health care services
to patients in neighborhood clinics
R01HL17332-04 Use of the gut for therapy of coronary
artery disease (mammals)
R01HL17341-03 Practical total synthesis of
prostaglandins
ROlHL-17408-03 Fresh blood rheology- Relation to
cardiovascular risk (human)
ROlHL-17580-04 The impact of stress on coronary heart
disease (men)
P50HL-17646-04 0010 Study of ischemic heart disease -
Compliance in ischemic myocardium -Altered cardiac
performance (human, dogs)
P50HL-17648-04 0004 Study of ischemic heart disease •
Radionuclide imaging studies (human, pig)
P50HL- 17648-04 0006 Study ol ischemic heart disease -
Ventricular performance and myocardial perfusion in
obstructive coronary disease
P50HL-1764804 0016 Study of ischemic heart disease -
Intraventricular conduction -Effect of pacing on conduction
and automaticity
P50HL- 17648-04 0020 Study of ischemic heart disease -
Core pathology laboratory-lschemic heart disease (human.
animal)
P50HL17651-04 Ischemic heart disease specialized center
of research
P50HL17655-04 0006 Study of ischemic heart disease -
Evaluation of coronary artery bypass graft surgery (human)
P50HL- 17655-04 0011 Study of ischemic heart disease ■
Core facility-Cardiovascular nuclear medicine (human, dog)
P50HL- 17665-04 Study of ischemic heart disease
P50HL-17665-04 0018 Study of ischemic heart disease -
Computer correlation of data -Patients with ischemic heart
disease
P50HL1 7667-04 Study of ischemic heart disease
P50HL- 17667-04 0001 Study of ischemic heart disease -
Natural history of ischemic heart disease (human)
P50HL1 7667-04 0019 Study of ischemic heart disease -
Assessment of long-term results of coronary artery bypass
grafting (human)
P50HL1 7667-04 0038 Study of ischemic heart disease -
Clinical core unit
P50HL-17667-04 0039 Study of ischemic heart disease ■
Core human investigative laboratories
P50HL- 17667-04 0040 Study of ischemic heart disease -
Core biochemistry-Cardiac metabolism (human)
P50HL-17667-04 0041 Study of ischemic heart disease -
Biophysical sciences core -Data collection and retrieval
P50HL-17667-04 0044 Study of ischemic heart disease -
Core-Data management and analysis
P50HL- 17670-04 Study of ischemic heart disease
P50HL-1767004 0001 Study of ischemic heart disease -
Data management
P50HL-17670-04 0005 Study of ischemic heart disease -
Quantitative assessment of the vectorcardiogram (human)
P50HL-17670-04 0008 Study of ischemic heart disease -
Surgical treatment of cardiac rhythm disorders (human,
dogs)
P50HL-1 7670-04 0012 Study of ischemic heart disease -
Epidemiology of sudden death (human)
P50HL-17670-04 0015 Study of ischemic heart disease ■
Radionuclide studies of myocardial ischemia (human)
P50HL- 17670-04 0016 Study of ischemic heart disease -
Core pathology laboratory (human, dogs, monkeys)
P50HL-17670-04 0017 Study of ischemic heart disease -
Core enzymology laboratory (human)
P50HL-17670-04 0018 Study of ischemic heart disease -
Core electrocardiogram laboratory (human)
P50HL- 17682-04 Study of ischemic heart disease
ROlHL-17759-03 Studies of myocardial reactive hyperemia
(dogs, human)
ROlHL-1780904 Effects of exercise on the coronary
vasculature (rat, dog)
ROlHL-18060-04 Exercise and coronary atherosclerotic
heart disease (monkeys)
(contd)
HEA
246
HEA
" ROlHL-18235-03 Cardiovascular fitness and other risk
factors (human)
** P50HL-18318-03 0018 Pathogenesis and complications of
hypertension - Plasma renin activity in chronic ischemic
heart disease (human)
** ROlHL-18589-03 Psychosocial factors and outcome in
coronary disease (human)
** ROlHL-18692-03 Glycosaminoglycans and lipoproteins of
human plasma
" ROlHL-18783-04 Detection and control of ventricular
premature beats (human)
** ROlHL-18800-04 Prospective study of resuscitated sudden
death victims (human)
** ROlHL-18805-04 0004 Sudden cardiac death and the
onset of myocardial infarction - Sudden death survivors-
Clinical follow-up and therapy (human)
" ROlHL-18805-04 0007 Sudden cardiac death and the
onset of myocardial infarction - Analysis of pathologic
factors involved in sudden death (human)
R01HL18850 03 Classification code for Frank orthogonal
ECG
" ROlHL-19089-03 Diastolic properties of the left ventricle
(human, dogs)
** ROlHL-19109-03 Regression of chronic atherosclerosis
(rabbits)
** R01HL191 12-03 Atherosclerosis studies (monkeys)
P50HL-19170-02 0001 Harvard pulmonary SCOR -Chronic
diseases of the airways - Natural history, reversibility of
pulmonary abnormalities in smokers (human)
" ROlHL-19202-03 Adenosine, prostaglandins in relation to
coronary flow (guinea pigs)
ROlHL-19218-03 Local regulation of coronary flow by
prostaglandins (rabbits)
ROlHL-19370-03 Coronary capillary exchange -The effects
of ischemia (dogs, sheep)
M ROlHL-19451-03 Functional characteristics of the left
heart
** R01HL19451-03 0003 Functional characteristics of the
left heart ■ Left ventricular segmental contraction (human,
dogs)
** ROlHL-19451-03 0004 Functional characteristics of the
left heart - Quantitative coronary arteriography (human)
** ROlHL-19567-03 Impact of emotion on coronary arteries
(human)
** ROIHL- 19839-09 Factors in youth predisposing to chronic
diseases (former college students)
** ROlHL-19974-02 Psychologic-behavioral Influences on
heart pathology (rats)
** ROlHL-20080-02 Surgically induced myocardial edema
(dogs)
** ROlHL-20374-03 Myocardial function -Risk factors and
future CHD (human)
" ROlHL-20428-03 The juvenile diabetic heart (human)
** ROlHL-2059702 Electrophysiologic correlates of
myocardial ischemia (human, dogs, rabbits)
** ROlHL-20662-02 Physical activity, fitness and
epidemiology of CHD
ROlHL-20787-02 Thromboxanes and prostaglandins -
Biochemical pharmacology (rabbits, human)
ROlHL-20807-02 Detection of familial hypercholesterolemia
(human)
ROlHL-20895-03 0001 Cineangiographic studies of
cardiovascular system - ViUeodensitometry and valvular
regurgitation (human, dogs)
** ROlHL-20895-03 0002 Cineangiographic studies of
cardiovascular system - Coronary disease-Regional
myocardial blood flow (human, dog)
ROlHL-20895-03 0006 Cineangiographic studies of
cardiovascular system • Cardiomyopathy -Hemodynamic,
radiologic, morphologic abnormalities (dog, rabbit)
ROlHL-20910-02 The alternative diet for coronary disease
prevention (human)
ROlHL-20924-02 Atherosclerosis and arterial cell functions
(human, rabbits)
** P50HL-2 1006-02 0005 Specialized center of research in
arteriosclerosis - Regional myocardial perfusion in patient
with coronary artery disease (also dogs)
*• ROlHL-21010-02 Glycemia, other traits and CV death in
40,000 persons
ROlHL-2126002 Risk factor relationships of
atherosclerosis (monkeys)
** ROlHL-21278-01 Abnormal cardiac wall motion viewed
ultrasonically (human, dogs, phantoms)
** ROlHL-21293-02 Randomized study of coronary bypass
surgery (human)
** ROlHL-21319-02 Interpersonal stress and coronary-prone
behavior (human)
** ROlHL-21654-01 Autonomic determinants of arrhythmia
due to ischemia (cats)
ROlHL-21912-01 Biosynthesis of lipoic acid and
atherosclerosis (birds, chick embryos)
** R23HL-21973-01 Catecholamine metabolism and the heart
(human, guinea pigs)
** R23HL-22004-01 Imaging and ECG studies in acute and
chronic IHD (human)
ROlHL-22255-01 The etiology/prevalence of peripheral
arterial disease (human)
" ROlHL-22378-01 Psyco-somatic predictors of CHD in
adolescence (human)
ROlHL-22445-01 Platelet inhibitors -Effect on coronary
bypass grafts (dogs)
** ROlHL-22514-01 Behavior patterns, stress, and
catecholamines
R01HL-225e7-01 Validation of a cholesterol absorption
method in man
** R23HL-22669-01 Cardiovascular effects from visceral
afferents (dogs)
ROlHL-22740-01 Behavior and cardiovascular disease-
Basic mechanisms (human)
ROlHL-227 50-01 Digoxin in heart failure with sinus
rhythm (human)
R01HL-227S9-01 Regional myocardial blood flow during
hypothermia (dogs)
ROlHL-22801-01 Analysis of coronary artery behavior
(dogs)
ROlHL-22809-01 Coronary-prone behavior and
cardiovascular reactivity (human)
ROlHL-22946-01 Prostaglandins, platelet aggregation and
vasoactivity (human, rats, rabbits)
" ROlHL-23078-01 Psychosocial stress and sudden coronary
death (human)
** NOlHV-12156-10 Lipid research clinic
** NOlHV-12157-14 Lipid research clinic (human)
** NOlHV-12 158-10 Establishment of a lipid research clinic
" NOlHV-12 159-09 Lipid research clinic
** NOlHV-12160-15 Establishment of a lipid research clinic
** NOlHV-22913-09 Lipid research clinic
** NOlHV-229 14-08 Establishment of a lipid research clinic
" NOlHV-229 15-11 Establishment of lipid research clinic
N01HV-229ie-16 Establishment of a lipid research clinic
NOlHV-22917-11 Lipid research clinic (human)
" N01HV-22932-09 Establishment of a lipid research clinic
** NOIHV 22971-07 Prevention of coronary heart disease
(human)
** NOIHV 22976-07 Multiple risk factor intervention trial,
prevention of coronary heart disease
** NOlHV-22977-08 Intervention trial for the prevention of
coronary heart disease (human)
** NOlHV-22979-07 Intervention trial for the prevention of
coronary heart disease (human)
** NOlHV-22980-06 Intervention trial for the prevention of
coronary heart disease (human)
** NOlHV-22981-10 Intervention trial for the prevention of
coronary heart disease (human)
** NOlHV-22982-07 Intervention trial for prevention of
coronary heart disease (human)
** NOlHV-22983-07 Intervention trial for the prevention of
coronary heart disease (human)
** NOlHV-32931-09 Establishment of a lipid research clinic
center
NOlHV-32975-08 Collaborative studies on coronary artery
surgery (human)
NOlHV-32976-09 Collaborative studies on coronary artery
surgery (human)
NOlHV-32980-07 Collaborative studies on coronary artery
surgery (human)
NOlHV-32981-10 Collaborative studies on coronary artery
surgery (human)
NOIHV-32983-11 Collaborative studies on coronary artery
surgery (human)
NOlHV-32984-10 Collaborative studies on coronary artery
surgery (human)
** NOlHV-33101-06 Development and conduct of a multiple
risk factor intervention trial (human)
** NOlHV-33 105-09 Intervention trial for prevention of
coronary heart disease (human)
** NOlHV-33106-06 Intervention trial for the prevention of
coronary heart disease (human)
** NOlHV-33108-04 Prevention of coronary heart disease
(human)
•* NOlHV-33109-04 Intervention trial for the prevention of
coronary heart disease (human)
** NOlHV-331 10-04 Prevention of coronary heart disease
(human)
** NOlHV-42902-08 Epidemiological studies of coronary heart
disease (human)
** NOlHV-42911-07 ECG center for prevention of coronary
heart disease (human)
** NOlHV-42929-08 Risk factor intervention trial for the
prevention of CHD (human)
" NOlHV-42930-09 Risk factor intervention trial for the
prevention of CHD (human)
** NOlHV-42931-07 Risk factor intervention trail for the
prevention of CHD (men)
** NOlHV-42932-05 Risk factor intervention trial for the
prevention of CHD (human)
** NOlHV-42933-09 Multiple risk factors in coronary heart
disease (human)
N01HV-S2901-06 Aspirin-myocardial infarction study
** NOlHV-52941-04 Center for aspirin-myocardial infarction
study (human)
** NOlHV-62955-04 Data collection in clinical pathology and
morbid anatomy (men)
HEART DISORDERS, CORONARY, ANGINA
PECTORIS
SEE ALSO HEART DISORDERS, CORONARY, MYOCARDIAL
ISCHEMIA AND HYPOXIA
POlHL-06285-18 0156 Cardiovascular-respiratory
physiology and biochemistry - Myocardial performance
following revascularization (human)
POlHL-06296-18 0003 Cardiovascular and pulmonary
adaptation to stress - Human exercise studies (human,
dogs)
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Oriented significanthf to above subject.
M Grant has subprojects describing
See Appendix for investigator's nam
POlHL-08682-15 0018 Regulation of the cardiovascular
system - Functional implications of cardiac afferent nerves
(dogs)
POlHL-11310-12 0092 Mechanisms of cardiovascular
disease - Exercise electrophysiology (human)
POlHL-13737-07 0037 Assisted circulation - Clinical
measurement of blood flow through aorto-coronary vein
bypass graft
ROlHL-14148-07 0009 The regional circulations -
Myocardial circulation in hypertension and atherosclerosis
(human)
ROlHL-14378-07 Lipemias and reconstructive cardiac
surgery (human)
'* ROIHL 15191-07 Multiparameter methods for
cardiovascular research
POlHL-15194-07 0020 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation in
arteriographically normal arteries (human)
ROlHL-15231-05 Mechanisms of hemodynamic changes
during digestion (dogs)
** ROlHL-16412-04 Release of nucleosides from the ischemic
heart (human, dogs)
P50HL- 17648-04 0004 Study of ischemic heart disease ■
Radionuclide imaging studies (human, pig)
P50HL- 17648-04 0012 Study of ischemic heart disease -
Retrograde coronary venous perfusion-Acute myocardial
ischemia
P50HL 17651-04 0002 Ischemic heart disease specialized
center of research - Reduction of myocardial ishemic injury
by pharmacologic agents (human, dog)
P50HL-17651-04 0046 Ischemic heart disease specialized
center of research - Clinical core-Physiological
changes/biochemical effects of myocardial ischemia
P50HL-1 7655-04 0004 Study of ischemic heart disease ■
Coronary arteriography in survivors of acute myocardial
infarction (human)
PSOHL-1 7655-04 0006 Study of Ischemic heart disease -
Evaluation of coronary artery bypass graft surgery (human)
" P50HL- 17655-04 0009 Study of ischemic heart disease -
Random trial of medical and surgical therapy in unstable
angina (human)
P50HL-1 7655-04 0011 Study of ischemic heart disease -
Core facility-Cardiovascular nuclear medicine (human, dog)
P50HL-17665-04 0003 Study of ischemic heart disease -
Quantitation of injury-Acute myocardial infarction
complicated by shock (human)
** P50HL- 17665-04 0005 Study of ischemic heart disease -
Evaluation of zone of jeopardized myocardium in patients
with angina pectoris
** P50HL- 17665-04 0013 Study of ischemic heart disease •
National cooperative study in unstable angina pectoris
(human)
P50HL-17665-04 0018 Study of ischemic heart disease -
Computer correlation of data-Patients with ischemic heart
disease
P50HL-17665-04 0022 Study of ischemic heart disease -
Effect of coronary revascularization on left ventricular
function (human)
P50HL-17667-04 0001 Study of Ischemic heart disease -
Natural history of ischemic heart disease (human)
P50HL-17667-04 0018 Study of ischemic heart disease -
Arrhythmias in ischemic heart disease (human)
P50HL-1 7667-04 0038 Study of ischemic heart disease ■
Clinical core unit
P50HL- 17669-04 0008 Ischemic heart disease center
(SCOR) - Segmental ventricular dysfunction during stress-
induced ischemia (dog, human)
P50HL-17669-04 0013 Ischemic heart disease center
(SCOR) - Exercise in patients with Ischemic heart disease
P50HL-1 7669-04 0023 Ischemic heart disease center
(SCOR) - Patients with acute myocardial infarction and
myocardial ischemia (human)
P50HL-17670-04 0014 Study of ischemic heart disease -
Real time ultrasound imaging in ischemic heart disease
(human, dog)
P50HL-17670-04 0015 Study of ischemic heart disease -
Radionuclide studies of myocardial ischemia (human)
P50HL-17682-04 0001 Study of ischemic heart disease -
Studies in acute and chronic ischemic heart disease
(human)
P50HL- 17682-04 0003 Study of ischemic heart disease -
Effects of myocardial revascularization in man
** P50HL-17682-04 0008 Study of ischemic heart disease -
Clinical core unit
R01HL18190-03 Myocardial blood flow in acute
myocardial infarction (human, dogs)
ROlHL-18783-04 Detection and control of ventricular
premature beats (human)
P50HL-18828-03 0005 Specialized center of research in
thrombosis - Platelet inflammatory factors in thrombosis
(human, guinea pig)
** ROlHL-18984-01 P50 effect on exercise limit in stable
angina (human)
** ROlHL-19089-03 Diastolic properties of the left ventricle
(human, dogs)
ROlHL-19451-03 0004 Functional characteristics of the
left heart - Quantitative coronary arteriography (human)
ROIHL- 19839-09 Factors in youth predisposing to chronic
diseases (former college students)
ROlHL-20598-03 The coronary vascular response to
ischemia (dogs, pigs)
(contd)
specific research aspects,
e and grant number.
HEA
PSOHL 2100602 GODS Sptciiliiad csntsi of raseiich in
•rtiiloscltrojis Regional myocardial perfusion in patient
with coronary artery disease (also dogs)
R01H12117202 Regional oxygen consumption ot tieart
and other organs (animals)
ROIHI 21293 02 Randomiied study ol coronary bypass
surgery (human)
ROIHL 2168402 OOOS Radionuclide infarct sizing and
therapy evaluation Clinical evaluation of radioisotope
imaging methods for quantifying infarct size
R01Hl'217Sl-02 0002 Thallium and antimyosin m
ischemia and infarction Canine models of ischemia and
infarction
R01HL21751'O2 0003 Thallium and antimyosin in
ischemia and infarction Human studies "Ischemia and
intarctron
ROIHL'21817 01 Catecholamines, blood pressure and
circulation
** R23HL'2I973-01 Catecholamine metabolism and the heart
(human, guinea pigs)
" R23ltL'22669-01 Cardiovascular effects from visceral
afferents (dogs)
ROlHL-22718-01 Cardiovascular drug interactions-
Metabolism models (dogs)
** ROIHL'22732'01 Central organization of cardiac afferent
nerves (cats. monKeys)
N01HV-S3010'03 NASNRC twin registry
** N01HV'S3027'0S Data coordinating center for the unstable
angina pectoris study
HEART DISORDERS, CORONARY, MYOCARDIAL
INFARCT
SEE ALSO HEART DISORDERS DIAGMOSIS, MYOCARDIAL
INFARCT SIZING
ROIHL'01803'23 0015 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Immunologic endothelial injury and lipid
diet atherosclerosis (rabbits, monkey)
•• R01HL03180-21 Relation of lymphatics to
cardiopulmonary function (dogs)
ROlHL-04666-19 Artificially paced hearts-Technology,
physiology (human, dogs)
R01HL-0S806'18 Analysis of antiarrhythmic agents (dogs,
rabbits)
** P01HL0628518 0164 Cardiovascular-respiratory
physiology and biochemistry - CPK MB Isoenzyme
concentration to quantify infarct size (human, animals)
POlHL-06296-18 0002 Cardiovascular and pulmonary
adaptation to stress - Respiratory muscle blood flow,
mechanics and metabolism (human, dog)
** P01HL-06308'I8 0035 Mechanisms and therapy of
circulatory disease - Mechanisms for electrophysiological
changes in myocardial infarction (dogs)
** POlHL-06308-18 0042 Mechanisms and therapy of
circulatory disease - Echocardiographic assessment of
arrhythmias-Myocardial tissue type (human, dogs)
•* POlHL-06308-18 0043 Mer'-anisms and therapy of
circulatory disease - Exercise and echocardiographic
examining techniques (human)
•* POlHL-06312-17 0016 Surgical cardiology ■ Effect of
hydralazine on infarct size following coronary occlusion
(human)
POlHL-06312-17 0025 Surgical cardiology • Effect of
denervation on arrhythmias and function with coronary
occlusion (dogs)
** POlHL-06370-17 0014 Cardiopulmonary and renal
pathology research center - Quantitative morphology in
cardiac disease (human, rats, dogs)
** POlHL-06664-17 0034 Cardiopulmonary function in
remediable vascular disease - Role of hyperosmolar agents
in ischemic heart disease (dogs)
** R01HL-07139-I7 Cardiodynamics and metabolism of
congestive failure (human, dogs)
** ROlHL-0777615 Sudden death and cardiac arrhythmias
(human, dogs, cats)
" POlHL-10539-12 0031 Pathophysiology of circulation -
Post myocardial infarction care-Psychological aspects
(human)
** POlHL-10539-12 0064 Pathophysiology of circulation •
Exercise physiology and pathophysiology (human)
** POlHL-1131012 0078 Mechanisms of cardiovascular
disease - Ventricular arrhythmias in acute myocardial
infarction (dogs)
POlHL-1 1310-12 0091 Mechanisms of cardiovascular
disease - Noninvasive techniques in cardiovascular
diagnosis (human)
POlHL-1 1310-12 0093 Mechanisms of cardiovascular
disease - Multiple dipole electrocardiogram project (human,
dogs)
** POlHL-11310-12 9001 Mechanisms of cardiovascular
disease - Core support-hospital beds
POlHL-1 1351-12 0004 Cellular and molecular
mechanisms of myocardial function - Molecular
mechanisms of contractile function and differentiation
(animals)
** POlHL-11414-11 0034 Thrombosis and atherosclerosis
program - Servo simulation -Experimental myocardial
infarction (dogs)
** POlHL-11678-11 0020 Cardiovascular dynamics and their
control - Circulatory and pulmonary fluid dynamics during
pulmonary edema
ROlHI-11876-11 Regional myocardial blood flow and
metabolism (dogs, swine)
Physiologic pharmacology and its
Coronary occlusions and arrhythmias
Regulation of the circulation in
Experimental myocardial infarction
Pathophysiology of myocardial ischemia
Mechanical behavior of left ventricle
247
ROIHL 12322 10 Extrinsic lactori Influencing myocardial
performance (dogs, swine)
ROIHL 1241b 10 Evaluation of left ventricular function
(dogs, rabbits)
ROIHL 12611 10 Basic and clinical studies ol the ST T
deflection (human, dogs)
POIHL 12738 10 0081 Physiologic pharmacology and its
clinical applications Ultraslructural and electrophysiologic
alteration of myocardium (human, dogs)
POIHL 12738 10 0117 Physiologic pharmacology and its
clinical applications Ventricular arrhythmias in ischemic
heart disease (human)
POIHL 12738 10 0127 Physiologic pharmacology and its
clinical applications Cardiac electrical activity (human,
animals)
POIHL 12738 10 0132
clinical applications
(dogs)
POIHL 13330-08 0059 Mechanical circulatory support
Physiologic evaluation of circulatory assistance (cattle)
ROlHL-13426-09 Left ventricular bypass for myocardial
infarction (cattle, human)
POIHL 13480-09 0017 Cardiac electrophysiology Body
surface potential mapping (human, dogs)
POIHL 13737 07 0030 Assisted circulation Myocardial
ischemia -Effects of phase-shift balloon pumping (dogs)
POlHL-13737-07 0036 Assisted circulation - Assessment
of infarct size from hemodynamic measurements
POlHL-13851-16 Cyclotron produced isotopes in biology
and medicine (human, animals)
P50HL-14141-05 0001 SCOR for atherosclerosis in
childhood - Clinical implications (Infants and children)
ROlHL-14148-07 0009 The regional circulations -
Myocardial circulation in hypertension and atherosclerosis
(human)
POlHL-14388-07 0218 Regulation of the circulation in
pathological states - Regional myocardial dyskinesis -Cause
assessment and reduction (dogs)
' POlHL-14388-07 0219 Regulation of the circulation in
pathological states - Myocardial ischemia and Infarction in
animals (dogs)
' POlHL-14388-07 0221
pathological states
(dogs)
' ROlHL-14571-05 Myocardial preservation and coronary
reperfusion (baboons, dogs)
* ROIHL 14646-05
(dogs, rats)
ROIHL-1465105
(dogs, rats)
ROlHL-14692-06 Alpha 1 antitrypsin deficiency and
pulmonary disease (human)
ROlHL-14785-07 Ultrasonic scattering for tissue
characterization (dogs, cattle, human)
ROlHL-14899-07 Mechanism and prevention of cardiac
arrhythmias (dogs)
ROlHL-15016-07 New concepts in cardiac ultrasound
technology (human)
ROlHL-15047-06 Digital computer analysis of the
electrocardiogram (human)
POlHL-15194-07 0011 Pathophysiology of
cardiopulmonary dysfunction - Distribution of ventilation-
Oxygen effects on intrapulmonary shunting (human)
* POlHL-15194-07 0025 Pathophysiology of
cardiopulmonary dysfunction - Myoglobinemia as an Index
of myocardial ischemia and infarction
ROlHL-15247-05 Extending the life of implanted
pacemakers (dogs, human)
ROlHL-15308-07 Assays for peptides of lipoproteins
(human)
ROlHL-15374-03 Cooperative study of drugs and coronary
heart disease (human)
ROlHL-154 16-06 Cardiovascular control in normal and
disease states (dogs, baboons)
* ROlHL-15498-06
(rats)
* ROlHL-15607-06
circulation (dogs)
ROlHL-15622-05
dogs)
* ROlHL-15790-06
attacks (human)
* ROlHL-16076-06 Electrophysiology of fibrillation and
defibrillation (human)
ROlHL-16246-06 Immunologic studies in
postpericardiotomy syndrome (human)
* R01HL-16553-05 Diagnosis of myocardial infarction by
radioisotopes (mice, rats, goats)
* ROlHL-16901-05 Multipolar linkage between heart
geometry and surface (human, dogs)
* P60HL-17269-04 0007 National heart and blood vessel
research and demonstration center - Correlative studies of
experimental myocardial ischemic (dog)
P60HL-17269-04 0023 National heart and blood vessel
research and demonstration center - Cardiovascular
pharmacology-Ischemia, shock and heart failure (dog, cat,
rat)
P60HL-172e9-04 0029 National heart and blood vessel
research and demonstration center - Clinical application of
circulatory assistance (human)
Effects of physical training on heart
Physiological control of splanchnic
Computer simulation in cardiology (rats.
Follow-up study of acute coronary heart
HEA
P60HL 17269 04 0033 National heart and blood vetial
research and demonstration center Autoallergic retpont*
in cardiomyopathy, atherosclerosis, rheumatic heart diuate
ROIHL 17452 04 Depolarization Induced cardiac
automaticity (human, animals)
ROIHL 17532 04 Infarct size ECG, angio. path, correlation
in dogs
P50HL 17646 04 Study ot ischemic heart disease
P50HI 17646 04 0001 Study of ischemic heart disease
Core clinical investigation unit
P50HL 1 7646 04 0002 Study ol ischemic heart diuate -
Core data management
P50HL 17646 04 0004 Study of ischemic heart disease -
Core experimental animal laboratories
P50HL 17646 04 0005 Study of ischemic heart disease
Biochemical markers and mediators of myocardial ischemic
injury
P50HL 17646 04 0006 Study of ischemic heart disease
Mathematical models for predicting infarct size using CPK
and other markers
P50HL 1764604 0007 Study of ischemic heart disease •
Prediction of myocardial ischemic injury by analysis of
plasma CPK isoenzymes
P50HL 17646-04 0010 Study of ischemic heart disease -
Compliance in Ischemic myocardium-Altered cardiac
performance (human, dogs)
P50HL- 17646-04 0012 Study of ischemic heart disease ■
Role of microcirculation in progression of myocardial
ischemic injury (rat)
P50HL 17646-04 0013 Study of ischemic heart disease -
Maintenance of myocardial vascular integrity after
revascularization (dogs)
P50HL-17646-04 0014 Study of ischemic heart disease ■
Progression of ischemic injury in conscious dogs (also
rabbits)
P50HL- 17646-04 0015 Study of ischemic heart disease -
Protecting ischemic myocardium In patients with evolving
myocardial infarction
' P50HL-1 7646-04 0017 Study of ischemic heart disease ■
Dysrhythmia associated with acute myocardial infarction
(human, cat)
P50HL- 17648-04 Study of ischemic heart disease
P50HL- 17648-04 0004 Study of ischemic heart disease -
Radionuclide Imaging studies (human, pig)
' P50HL-17648-04 0011 Study of ischemic heart disease -
Surgical treatment for acute myocardial ischemia (human.
dogs)
PSOHL-1 7648-04 0012 Study of ischemic heart disease -
Retrograde coronary venous perfusion-Acute myocardial
ischemia
' P50HL-17648-04 0018 Study of Ischemic heart disease -
Myocardial damage-Infarction vectors recalled by
premature atrial stimulation
P50HL- 17648-04 0020 Study of ischemic heart disease -
Core pathology laboratory-lschemic heart disease (human.
animal)
' PSOHL-17648-04 0021 Study of ischemic heart disease -
Biventricular contractile responses to acute myocardial
infarction (mammals)
' P50HL-17648-04 0023 Study of ischemic heart disease -
Chemical mediators of inflammation In acute myocardial
infarction (mammals)
P50HL-1 7651-04 Ischemic heart disease specialized center
of research
* P50HL-1765I-04 0015 Ischemic heart disease specialized
center of research - Peripheral circulation In acute
myocardial ischemia and infarction (human)
' P50HL- 1765 1-04 0016 Ischemic heart disease specialized
center of research - Retroperfusion of coronary venus
circulation with therapeutic agents (dogs)
P50HL-17651-04 0023 Ischemic heart disease specialized
center of research - Development of multipurpose catheter
for monitoring and electronic pacing
P50HL-17651-04 0036 Ischemic heart disease specialized
center of research - Core facilities-Cardiovascular
pathology (human, dog)
P50HL-17651-04 0038 Ischemic heart disease specialized
center of research - Cardlothermography (human, dog)
* P50HL-17651-04 0039 Ischemic heart disease specialized
center of research - Measurement and prediction of infarct
size (human, dog)
P50HL-17651-04 0044 Ischemic heart disease specialized
center of research - Limb blood flow after myocardial
revascularization (human)
* P50HL-17651-04 0045 Ischemic heart disease specialized
center of research - Peripheral vascular studies-
Pharmacology (dogs, human)
P50HL-17651-04 0046 Ischemic heart disease specialized
center of research - Clinical core-Physiological
changes/biochemical effects of myocardial Ischemia
I P50HL-17655-04 Study of Ischemic heart disease
* P50HL-17655-04 0001 Study of Ischemic heart disease -
Intravenous nItroglycerin-Ventrlcular function and infarct
size (human, dog)
* P50HL-17665-04 0004 Study of ischemic heart disease -
Coronary arteriography in survivors of acute myocardial
Infarction (human)
P50HL-17655-04 0006 Study of ischemic heart disease -
Evaluation of coronary artery bypass graft surgery (human)
* P50HL-17655-04 0010 Study of ischemic heart disease -
Core facility-Cardiovascular pathology (human, animal)
(contd)
*Eacliides routine metlKidok)gy OR cavers only general projects which preclude indexing at the specific level
**0nenttd significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
^^7%
HEA
P50HL-17655-04 0011 Study of ischemic heart disease -
Core facihtyp-Cardiovascular nuclear medicine (human, dog)
P50HL-17655-04 0014 Study of ischemic heart disease -
Blood flow and gas tension in myocardial ischemia and
infarction (dog, monkey)
M P50HL-1 7665-04 Study of ischemic heart disease
♦• P50HL17665-04 0001 Study of ischemic heart disease -
Reduction of acute anterior myocardial infarction -
Mechanical circulatory assist
** P50HL-17665-04 0002 Study of ischemic heart disease -
Reducing acute anterior myocardial infarction-Beta
adrenergic blockade (human)
** P50HL-17665-04 0003 Study of ischemic heart disease -
Quantitation of Injury-Acute myocardial infarction
complicated by shock (human)
" P50HL-17665-04 0005 Study of ischemic heart disease -
Evaluation of zone of jeopardized myocardium in patients
with angina pectoris
P50HL-17665-04 0008 Study of ischemic heart disease ■
Core laboratory -CPK isoenzyme measurement and
myocardial necrosis evaluation
** P50HL-1766504 0011 Study of ischemic heart disease -
Development of new methods for the determination of
infarct size (dog, human)
P50HL-17665-04 0012 Study of ischemic heart disease -
Myocardial ischemia -Cardiovascular performance in the
conscious baboon and dog
P50H1.-17665-04 0018 Study of ischemic heart disease -
Computer correlation of data-Patients with ischemic heart
disease
P50HL-1 7665-04 0028 Study of ischemic heart disease -
Pathologic and biochemical studies of ischemic
myocardium (human, dog)
** P50HL-17665-04 0032 Study of ischemic heart disease -
Myocardial infarct sizing -Immunoassay for cardiac myosin
light chains (dogs)
P50HL-17667-04 0001 Study of ischemic heart disease -
Natural history of ischemic heart disease (human)
P50HL-1766704 0018 Study of ischemic heart disease -
Arrhythmias in ischemic heart disease (human)
P50HL-17667-04 0019 Study of ischemic heart disease -
Assessment of long-term results of coronary artery bypass
grafting (human)
P50HL-17667-04 0031 Study of ischemic heart disease -
Pathophysiology in ischemic heart disease (dog, cat, rabbit,
monkey)
P50HL-17667-04 0038 Study of ischemic heart disease -
Clinical core unit
P50HL-17667-04 0040 Study of ischemic heart disease -
Core biochemistry-Cardiac metabolism (human)
** P50HL-1 7667-04 0043 Study of ischemic heart disease -
Quantitation of myocardial infarct size by serial enzyme
measurements (human)
** P50HL-1 7667-04 0045 Study of ischemic heart disease -
Pathology of myocardial ischemic necrosis (human)
M P50HL-1766904 Ischemic heart disease center (SCOR)
** P50HL-1 7669-04 0001 Ischemic heart disease center
(SCOR) - Radioimmunoassays for CPK isoenzyme and
myoglobin (human, dog)
** P50HL-1 7669-04 0002 Ischemic heart disease center
(SCOR) • Myocardial infarction sizing by radioimmunoassay
of cardiac myosin (dogs)
** P50HL-1 7669-04 0009 Ischemic heart disease center
(SCOR) - Infarct volume-99Tc stannous pyrophosphate
myocardial scintigrams (dogs, human)
P50HL-17669-04 0013 Ischemic heart disease center
(SCOR) - Exercise in patients with ischemic heart disease
** P50HL-17669-04 0022 Ischemic heart disease center
(SCOR) - Pathological studies of human and experimental
ischemic heart disease
** P50HL-17669-04 0023 Ischemic heart disease center
(SCOR) - Patients with acute myocardial infarction and
myocardial ischemia (human)
M P50HL-17670-04 Study of ischemic heart disease
** P50HL17670-04 0005 Study of ischemic heart disease -
Quantitative assessment of the vectorcardiogram (human)
P50HL-I7670-04 0008 Study of ischemic heart disease -
Surgical treatment of cardiac rhythm disorders (human,
dogs)
P50HL-1 767004 0009 Study of ischemic heart disease -
Surgical treatment of localized left ventricular dyssynergy
(human, dogs)
** P50HL-17670-04 0011 Study of ischemic heart disease -
Pharmacology of ischemic myocardium (dogs)
P50HL- 176 70-04 0012 Study of ischemic heart disease -
Epidemiology of sudden death (human)
P50HL- 17670-04 0014 Study of ischemic heart disease -
Real time ultrasound imaging in ischemic heart disease
(human, dog)
P50HL-17670-04 0015 Study of ischemic heart disease •
Radionuclide studies of myocardial ischemia (human)
P50HL-1 7670-04 0016 Study of ischemic heart disease -
Core pathology laboratory (human, dogs, monkeys)
P50HL-17670-04 0017 Study of ischemic heart disease -
Core enzymology laboratory (human)
** P50HL-17670-04 0021 Study of ischemic heart disease -
Enzymatic evaluation of acute myocardial infarction (dogs)
•* P50HL17670-04 0023 Study of ischemic heart disease -
Energy metabolism in acute myocardial ischemic injury
(dogs)
M P50HI- 17682-04 Study of ischemic heart disease
248
P50HL-17682-04 0001 Study of ischemic heart disease -
Studies in acute and chronic ischemic heart disease
(human)
** P50HL-17682-04 0003 Study of ischemic heart disease -
Effects of myocardial revascularization in man
** P50HL-17682-04 0007 Study of ischemic heart disease -
Mechanisms of hypoxemia in myocardial infarction (human)
** P50HL-17682-04 0008 Study of ischemic heart disease -
Clinical core unit
P50HL-17682-04 0009 Study of ischemic heart disease -
Computer core unit
** P50HL-17682-04 0010 Study of ischemic heart disease -
Core clinical enzyme laboratory (human, mice, dogs, rats)
** P50HL-17682-04 0011 Study of ischemic heart disease -
Nuclear medicine core unit (human, dogs, rabbits, mice)
** P50HL-17682-04 0012 Study of ischemic heart disease -
Pathology core laboratory (human)
** P50HL- 176 82-04 0013 Study of Ischemic heart disease -
Chronic ischemic heart disease -Myocardial function and
metabolism (dogs, swine)
** P50HL-17682-04 0015 Study of ischemic heart disease
Acute myocardial ischemia and infarction and their
reversibility (dogs, baboons)
** P50HL-17682-04 0016 Study of ischemic heart disease -
Endurance exercise-Prevention and rehabilitation in
ischemic heart disease (pig)
P50HL-17682-04 0021 Study of ischemic heart disease •
Prostaglandin biosynthesis in blood vessels from ischemic
myocardium (rat, sheep)
** ROlHL-17739-04 Acute myocardial infarct scintigraphy
(human, dogs, rats)
ROlHL-18003-05 Digitalis-Mechanism and reversal studies
(dog, sheep, duck, guinea pig, human)
ROlHL-18024-03 Regional myocardial flow and function
relationships (dogs)
** ROlHL-18190-03 Myocardial blood flow in acute
myocardial infarction (human, dogs)
ROlHL-18328-03 Hemoglobin function and tissue
oxygenation (human, dogs)
** ROlHL-18398-04 Mechanisms of delayed and asymetric
ventricular conduction (human, dogs)
** ROlHL-18537-04 Regional blood flow after acute
myocardial injury (dogs)
ROlHL-18538-03 The role of electrotonus in His-Purkinje
function (dog)
ROlHL-18687-03 Pathophysiology of genetic
hypertriglycerinemias (human)
** POlHL-18708-03 0010 Oxygen, energy and contractility in
cardiac tissue - Tissue oxygen utilization (rats, dogs)
ROlHL-18769-04 Studies in survivors of lethal arrhythmias
(human)
ROlHL-18776-04 Prevention of acute and fatal
cardiovascular disease (human)
** ROlHL-18793-03 Clinical-pathologic studies of sudden
cardiac death (human)
ROlHL-18796-04 Experimental cardiac arrhythmias (dogs)
ROlHL-1879804 0003 Nervous and ionic factors in
sudden cardiac death - Left stellectomy in the prevention
of sudden death (dogs)
ROlHL-18800-04 Prospective study of resuscitated sudden
death victims (human)
M ROlHL-18805-04 Sudden cardiac death and the onset of
myocardial infarction
ROlHL-18805-04 0001 Sudden cardiac death and the
onset of myocardial infarction - Predictive value of
maximum exercise stress testing (human)
** ROlHL-18805-04 0003 Sudden cardiac death and the
onset of myocardial infarction - Prediction from clinical and
laboratory assessments (human)
** ROlHL-18808-04 0001 Prediction and prevention of
sudden cardiac death - Prognostic significance of
premature ventricular contractions (human)
P50HL-18828-03 0005 Specialized center of research in
thrombosis - Platelet inflammatory factors in thrombosis
(human, guinea pig)
ROlHL-18850-03 Classification code for Frank orthogonal
ECG
** ROlHL-18907-03 Objective evaluation early after Ml and
heart surgery (human)
** ROlHL-19000-03 Irreversible myocardial injury (rats)
ROlHL-19030-03 Tissue protection during circulatory
interruption (dogs)
ROlHL-19045-03 Electrophysiology of cardiac automaticity
(human, dogs)
** ROlHL-19072-03 Modification of tissue injury in
myocardial infarction (dogs, human)
ROlHL-191 27-03 Synthesis of molecules for myocardial
imaging (rats)
** ROlHL-19232-03 ECHO changes in wall motion with
myocardial ischemia
ROlHL-19255-03 Evaluation of diagnostic clinical
hemorrheology (human)
** ROlHL-19343-03 Behavioral influences on cardiac
contractility (monkeys)
ROlHL-19451-03 0003 Functional characteristics of the
left heart - Left ventricular segmental contraction (human,
dogs)
** ROlHL-19537-03 Detection of myocardial injury with
ultrasound (dogs)
ROlHL-19782-02 Pharmacologic studies on the ischemic
heart (dogs)
HEA
ROlHL-19839-09 Factors in youth predisposing to chronic
diseases (former college students)
" ROlHL-20187-01 Evaluation of exercise cardiac
rehabilitation program (40-55 year old men)
ROlHL-20196-02 Regulation of coronary arterial smooth
muscle
** ROlHL-20199-02 Drug-induced alterations in infarct size
in the rat
ROlHL-20226-02 Cardiac bypass and coronary collateral
physiology (dogs)
ROlHL-20394-03 Complement activation by heart
subcellular membranes (human, dog)
ROlHL-20418-03 Serum cholesterol binding reserve in
diabetes (human)
ROlHL-20597-02 Electrophysiologic correlates of
myocardial ischemia (human, dogs, rabbits)
ROlHL-20630-03 Development of a pulsed Doppler velocity
detector (human, animals)
** ROlHL-20645-01 Etiology of myocardial infaction (human)
ROlHL-20872-02 Multidimensional echo imaging of the
ischemic heart
** ROlHL-20895-03 0005 Cineangiographic studies of
cardiovascular system - Computerized axial tomography-
Cardiac wall motion and infarction (dogs)
** ROlHL-21088-02 Genetic patterns in deaths from Ml and
stroke in Utah
R23HL-2115102 Ischemic myocardium-Delivery of blood
flow and drugs (dogs)
ROlHL-21 172-02 Regional oxygen consumption of heart
and other organs (animals)
** ROlHL-21283-02 Simulation studies of the ECG in acute
ischemia (and human)
" R23HL-21292-01 Human ventricular activation -Patterns
and mechanisms (human)
R23HL-2 1298-02 Coronary vasomotion (dogs, pigs)
** ROlHL-21418-02 Experimental myocardial infarction (rats)
** ROlHL-21425-02 Servo-simulated compliance changes-A
reversible Ml (dogs)
** ROlHL-2 1427-02 Behavioral changes in post infarction
patients
ROlHL-21533-02 Platelet inhibitor drug in coronary surgenr
(human)
ROlHL-21672-01 Antiarrhythmic drug action on VMAZ of
cardiac cells
M ROlHL-21684-02 Radionuclide infarct sizing and therapy
evaluation
" ROlHL-2168402 0001 Radionuclide infarct sizing and
therapy evaluation - Evaluating preservation of ischemic
myocardium by radioisotope methods (dog)
ROlHL-21684-02 0002 Radionuclide infarct sizing and
therapy evaluation - Evaluating myocardial imaging agents
in global and regional ischemia (rabbits)
** ROlHL-21684-02 0003 Radionuclide infarct sizing and
therapy evaluation - Core pathology laboratory (dogs,
human)
** ROlHL-2 1684-02 0004 Radionuclide infarct sizing and
therapy evaluation - Image analysis-Kinetics of infarction,
ventricular function (human, animal)
** ROlHL-21684-02 0005 Radionuclide infarct sizing and
therapy evaluation - Clinical evaluation of radioisotope
imaging methods for quantifying infarct size
** ROlHL-21690-02 Sequential multinuclide study of acute
infarction (human, dogs)
ROlHL-21697-01 Myocardium infarct sizing by 82Rb
emission tomography (dogs, human)
" ROlHL-21719-01 Computed cardiac tomography in infarct
sizing (dogs, human)
** ROlHL-2173501 Electrophysiology after healed myocardial
infarction (cats)
** ROlHL-21750-02 Electrocardiographic quantification of
infarct size (dogs, human)
M ROlHL-21751-02 Thallium and antimyosin in ischemia and
infarction
** ROlHL-21751-02 0001 Thallium and antimyosin in
ischemia and infarction - In vitro models of ischemia and
infarction (rats, mice)
** ROlHL-21751-02 0002 Thallium and antimyosin in
ischemia and Infarction - Canine models of ischemia and
infarction
** ROlHL-21751-02 0003 Thallium and antimyosin in
ischemia and infarction - Human studies-Ischemia and
infarction
** R23HL-21783-01 Ionic control of contractility in anoxic
myocardium (rabbits, rats)
** ROlHL-21793-02 Functional infarct size by gated
radioangiography (human, dogs)
ROlHL-21843-01 Ischemia, diabetes and the
microcirculation (rats, cats, hamsters)
** R23HL-22004-01 Imaging and ECG studies in acute and
chronic IHD (human)
ROlHL-22005-01 Intermittent retroperfusion of ischemic
myocardium (dogs)
ROlHL-22080-01 Phosphorus NMR studies on cardiac
tissue (rats, rabbits)
** ROlHL-22098-01 Is postoperative infarction due to
repertusion injury? (human, dogs)
ROlHL-22315-01 Intraoperative cardiac oxygen supply-
demand (dogs, rabbits, rats)
** ROlHL-22470-01 Liposome myocardial uptake in infarct
and ischemia (dogs. rats, mice)
R23HL-22575-01 Factors modifying cardiac digoxin effects
and content (dogs, cats)
(contd)
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
HEA
Psychosocial stress and sudden coronary
Myocardial ischemia (dogs. rats, chick
ROIHL 2281S01 Regional myocardial function attar
revBSCuiariiation (dogs)
ROlttl ??821 01 A routine screening analysis tor
myoglobinemia
ROIHL 2298201 Multicenter postcoronary risk
stratification program (human)
ROIHL 23071 01 Electrophysiology of lethal arrhythmias
(dog. human)
ROlHL-2307801
death (human)
ROlHL-23138 01
embryo)
ROIHL'23140 01 Determinants of irreversible ischemic
injury in heart (dog. rat)
ROIHl 23161 01 0005 Biology of myocardial ischemia
Localization of complement in myocardial infarction (dog)
ROltfL 2317101 Coronary collateral circulation in
myocardial Ischemia (dog. pig. rat. human)
ROIHL 2359901 Mechanisms of ischemic rhythm
disorders (dogs)
ROlHL-2365301 Protection of the ischemic myocardium
(dogs)
ROIHL 2397001 Mechanisms and control of sudden
cardiac death (human, dog)
ROlHL-2398201 Control of coronary flow by carbon
dioxide tension (dogs)
ROlHL-23983'01 Quantitative radiocardiography (human.
dogs)
NOlHV-42911-07 ECG center for prevention of coronary
heart disease (human)
NOIHV'52901'06 Aspirinmyocardial infarction study
NOIHV'5294104 Center for aspirinmyocardial infarction
study (human)
NOIHV'62960'00 Techniques to protect ischemic
myocardium and minimize infant size (human)
' NOlHV-72940-02 Therapy to protect ischemic myocardium
(human)
•* NOlHV-72948-03
trial (human)
** NOlHV-72949-03
*• NOlHV.72950-02
trial
•* NOlHV-7295103
(human)
** NOlHV-72952-02
(huamn)
** NOlHV-7295304
** NOlHV-72954-06
(human)
** NOlHV-72955-02
(human)
** NOlHV-72956-02
(human)
*• NOlHV-72957-02
(human)
•* NOlHV-72958-02
(human)
•* NOlHV-72959-04
(human)
" NOlHV-72960-02
(human)
♦* NOlHV-72961-03
•* NOlHV-72963-02
(human)
" NOlHV.72964-02
(human)
** N01HV-72965-02
** NOlHV-72966-03
" N01HV-72967-02
(human)
** NOlHV-72968-03
•* NOlHV-72969-02
(human)
** N01HV-72970-04
(human)
** NOlHV-82900-03
(human)
** NOlHV-82901-02
(human)
** N01HV.8290202
(human)
** N01HV-82903-C2
(human)
" NOlHV-82904-02
(human)
** NOlHV-82905-02
(human)
*♦ N01HV-82906-02
(human)
" N01HV-82907-02
(human)
** NOlHV-82908-02
(human)
** N01HV-82909-02
(human)
** NOlHV-82910-00
(human)
HEART DISORDERS, CORONARY, MYOCARDIAL
ISCHEMIA AND HYPOXIA
SEE ALSO HEART DISORDERS. CORONARY. ANGINA PECTORIS
Coordinating center for propranolol heart
ECG center for proprancolo heart trial
Central laboratorv for propranolol heart
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center (or propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center tor propranolol heart trail
Clinical center for propranolol heart trial
Clinical center propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
249
POIHL 04664 18 0011 Cirdiovasculai and lung dynamics
Detection of abnormal segments of the human ventricle
by measure of asynergy
P01HL04664 18 0013 Cardiovascular and lung dynamics
Ventricular function in coronary disease using NIG and
ventriculograms (human)
POIHL 04664 18 0014 Cardiovascular and lung dynamics
Clinical application of computer analysis of ventiiculai
wall motion
ROIHL 05806 18 Analysis of antiarrhythmic agents (dogs.
rabbits)
POIHL 06285 18 0143 Cardiovascular respiratory
physiology and biochemistry Myocardial ischemia (human,
dogs, lambs)
P01HL06285 18 0154 Cardiovascular respiratory
physiology and biochemistry Function and viability of
critically ischemic myocardium (dogs)
POIHL'06285 18 0156 Cardiovascular respiratory
physiology and biochemistry Myocardial performance
following revascularization (human)
POIHL 06296' 18 0005 Cardiovascular and pulmonary
adaptation to stress Regulation of ventricular
performance (animals)
POIHL-06308'18 0010 Mechanisms and therapy of
circulatory disease Ventricular arrhythmias during exercise
to CHO and myocardial ischemia (human)
POIHL 0630818 0011 (Mechanisms and therapy of
circulatory disease Blood (low and electrical dysfunction
in ventricular arrhythmia (human)
POlHL'06308-18 0029 Mechanisms and therapy of
circulatory disease - Characterization of the patient with
recurrent ventricular arrhythmias
P01HL-0e308-18 0037 Mechanisms and therapy of
circulatory disease Electrophysiology. blood flow, and ANS
in ventricular fibrillation (dogs)
POlHL-06308-18 0038 Mechanisms and therapy of
circulatory disease - Electrophysiology of ventricuair
arrhythmias associated with ischemia (dogs)
' POlHL-06308-18 0040 Mechanisms and therapy of
circulatory disease - Metabolism and fatty acid utilization-
Heart electrical stability (rats, dogs)
' POIHL-0630818 0042 Mechanisms and therapy of
circulatory disease • Echocardiographic assessment of
arrhythmias -Myocardial tissue type (human, dogs)
' P01HL0630818 0044 Mechanisms and therapy of
circulatory disease - Echocardiography to determine site of
ectopic impulse formation (human, dogs)
' POlHL-0631217 0013 Surgical cardiology ■ Aortocoronary
vein bypass grafting (human)
POlHL-0631417 0065 Immunologic mechanisms in
cardiovascular disease - Transplantation biology and
clinical transplantation
POlHL-06370-17 Cardiopulmonary and renal pathology
research center
' POlHL'06370-17 0014 Cardiopulmonary and renal
pathology research center - Quantitative morphology in
cardiac disease (human, rats, dogs)
POlHL-06664'17 Cardiopulmonary function in remediable
vascular disease
* P01HL0666417 0034 Cardiopulmonary function in
remediable vascular disease - Role of hyperosmolar agents
in ischemic heart disease (dogs)
' POlHL-06664-17 0036 Cardiopulmonary function in
remediable vascular disease - In vitro studies on the
mechanism of ischemic damage to cells (rabbits)
' ROlHL-07139-17 Cardiodynamics and metabolism of
congestive failure (human, dogs)
' R01HL-083I114 Effects of drugs upon myocardial hypoxia
(dogs, turtles)
POlHL'08682-15 0018 Regulation of the cardiovascular
system - Functional implications of cardiac afferent nerves
(dogs)
* ROlHL-093 15-15 Coronary insufficiency and myocardial
revascularization (human, dogs)
ROlHL-09364-14 Ion transport by heart mitochondria
(cattle, rat. rabbit)
* R01HL0956214 Cardiac protein synthesis, overload,
alcohol and anoxia (guinea pigs)
' R01HL0991413 The myocardium in diabetes mellifus
(dogs, monkeys)
ROlHL-10384-13 Blood flow and nucleotide metabolism
(animals)
POlHL-10436-13 0002 A multidisciplinary study of
congenital heart disease - Myocardial performance,
metabolism and ultrastructure (human, cats, rats)
POlHL-10436-13 0014 A multidisciplinary study of
congenital heart disease - Cardiovascular pharmacology
(dog)
ROlHL-10503-13 Cardiac ion transport and ultrastructure
(rats, guinea pigs, rabbits)
POlHL-10539-12 0023 Pathophysiology of circulation -
The relaxation response and therapy of disease states
(human)
* POlHL-10539-12 0067 Pathophysiology of circulation ■
Mechanical, electrophysiological studies-Isolated heart
muscle (dog, rat)
POlHL-10539-12 0068 Pathophysiology of circulation -
Acute and chronic cardiomyopathies (mice, dogs, hamsters,
human)
* POlHL-1 1307-12 0002 Biophysical studies in pediatric
cardiology - Cardiac extracellular electrophysiology (human,
dog, chimpanzee)
Physiologic pharmacology and its
Ventricular arrhythmias in ischemic
'Excludes routine methodok)gy OR covers only general prajects which preclude indexing
"Oriented significantly to atiove subject.
HEA
POIHL 11310 12 0063 Machinlimi of cirdlovaiculac
disease Myocardial function, metabolism and cellular
integrity after heart surgery (dogs)
POIHI 1 1310 12 0091 Mechanisms of cardiovascular
disease Noninvasive techniques in cardiovascular
diagnosis (human)
POIHL 11310 12 0092 Mechanisms of cardiovascular
disease Exercise electrophysiology (human)
POIHL 11310 12 0093 Mechanisms of cardiovascular
disease Multiple dipole electrocardiogram project (human,
dogs)
" POIHL 11310 12 9001 Mechanisms of cardiovascular
disease Core support hospital beds
" POIHL 11351 12 0002 Cellular and molecular
mechanisms of myocardial function Effects of hypoxia
and ischemia on ionic exchange (rats, rabbits)
** POIHL 11351 12 0015 Cellular and molecular
mechanisms of myocardial function Effects of hypoxia
and ischemia on ion exchange and heart function (rabbits)
ROIHL 11876 11 Regional myocardial blood flow and
metabolism (dogs, swine)
ROIHL 12322-10 Extrinsic factors influencing myocardial
performance (dogs, swine)
** ROIHL 12415-10 Evaluation of left ventricular function
(dogs, rabbits)
" ROIHI 1261110 Basic and clinical studies of the STT
deflection (human, dogs)
P01HL1273810 0044 Physiologic pharmacology and its
clinical applications Cardioactive drugs and
electrophysiological properties of cardiac cells (sheep)
" P01HL12738-10 0092 Physiologic pharmacology and its
clinical applications - Subendocardial ischemia following
open heart surgery (human)
POlHL-12738 10 0107 Physiologic pharmacology and its
clinical applications Blood superfused cardiac fibers
(dogs)
" POlHL-12738-10 0117
clinical applications
heart disease (human)
" P01HL1273810 0122 Physiologic pharmacology and its
clinical applications - Coronary perfusion of beating and
fibrillating hearts (dogs)
** P01HL12738-10 0124 Physiologic pharmacology and its
clinical applications - Counterpulsation on myocardial
ischemia measured by carbon dioxide tension (dogs)
** ROlHL-12777-09 Mechanisms in cardiac performance
(dogs, human)
R01HL13257'09 Inhalation anesthesia on myocardial
metabolism (dogs, swine, human)
P01HL1373707 0007 Assisted circulation -
Determination of cardiac status by use of balloon pump
(dogs)
POlHL-13737-07 0008 Assisted circulation - Phase-shift
balloon pumping alternate designs
P01HL1373707 0027 Assisted circulation - Optimization
of cardiac assistance (dogs)
** POlHL-13737-07 0030 Assisted circulation ■ Myocardial
ischemia-Effects of phase-shift balloon pumping (dogs)
** POlHL-13737-07 0031 Assisted circulation ■ Myocardial
ischemia-Biochemical changes (dogs)
" P01HL13737-07 0038 Assisted circulation ■
Distinguishing the ischemic ventricle from scarred ventricle
by balloon pumping
ROlHL-13870-09 Control of myocardial sarcotubular
calcium stores (dogs)
POlHL-14388-07 0179 Regulation of the circulation in
pathological states - Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
P01HL14388-07 0215 Regulation of the circulation in
pathological states ■ Lett ventricle model in
pathophysiologic states
POlHL-14388-07 0221 Regulation of the circulation in
pathological states - Experimental myocardial infarction
(dogs)
** ROlHL-14571-05 Myocardial preservation and coronary
reperfusion (baboons, dogs)
ROIHL'14644'05 Optimization diastolic augmentation and
systolic sink (dogs)
** ROlHL-14646-05 Pathophysiology of myocardial ischemia
(dogs, rats)
** ROlHL-14730-07 Fatty acid beta-oxidation in normal and
ischemic hearts (rabbits)
** POlHL-1519407 0025 Pathophysiology of
cardiopulmonary dysfunction - Myoglobinemia as an index
of myocardial ischemia and infarction
ROlHL-15416-06 Cardiovascular control in normal and
disease states (dogs, baboons)
ROlHL-15498-06 Effects of physical training on heart
(rats)
** R01HL1552206 Influence of mannitol on ischemia
cardiac muscle (dogs, cats, rats)
ROlHL-15622'05 Computer simulation in cardiology (rats,
dogs)
** ROlHL-15676-06 The role of occult myocardial failure in
human shock (human, dogs)
** R01HL15681-06 Coronary flow studies of partially
obstructed vessels (dogs)
ROlHL-15758-06 Catecholamine release in the heart
(dogs)
** ROlHL-15813-05 Cardiac anoxia-Protective effect of
carbohydrate (dogs)
** ROlHL-15983-04 Regional myocardial blood flow (dogs)
(contd)
at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
HEA
250
HEA
ROlHL-16292-05 Surgei) and non-obstructive coronary
insufficiency
ROlHL-16292-05 0002 Surgery and non-obstructive
coronary insufficiency - Effects of hypothermia during
cardiopulmonary bypass (dogs)
ROlHL-16292-05 0009 Surgery and non-obstructive
coronary insufficiency - Exercise and supply-demand
balance (human)
ROlHL-16292-05 0010
coronary Insufficiency
distribution (dogs)
ROlHL-16292-05 0017
coronary insufficiency
(human)
ROlHL-16292-05 0018
coronary insufficiency
Surgery and non-obstructive
Effects of exercise on flow
Surgery and non-obstructive
Cardiopulmonary resuscitation
Innervation of coronary arteries and heart
Dynamic control of coronary blood flow
Surgery and non-obstructive
Unavoidable subendocardial
perfusion caused by venting and hypothermia (dogs)
ROlHL-16292-05 0019 Surgery and non-obstructive
coronary insufficiency - Distortion of subendocardial vessels
in infant hearts (dogs)
ROlHL-16292-05 0020 Surgery and non-obstructive
coronary insufficiency - Limitation of transthoracic ECG in
detecting subendocardial ischemia (dogs)
ROlHL-16412-04 Release of nucleosides from the Ischemic
heart (human, dogs)
ROlHL-16511-04 Sympathetic afferent activity of cardiac
origin (dogs, monkeys)
ROlHL-16656-06 Left ventricular function in exercise
(dogs)
ROlHL-16657-06
(rats)
ROlHL-16760-05
(dogs)
PeOHL- 17269-04 0007 National heart and blood vessel
research and demonstration center - Correlative studies of
experimental myocardial ischemia (dog)
PeOHL-17269-04 0018 National heart and blood vessel
research and demonstration center - Mitochondria and
energetics (rabbits, dogs)
P60HL-17269-04 0019 National heart and blood vessel
research and demonstration center - Sarcoplasmic
reticulum (dog, rabbit, hamster, cat)
P60HL-17269-04 0021 National heart and blood vessel
research and demonstration center - Growth and
development of heart-Ultrastructure (dog, guinea pig, rat,
cat)
P60HL- 17269-04 0023 National heart and blood vessel
research and demonstration center - Cardiovascular
pharmacology-Ischemia, shock and heart failure (dog, cat,
rat)
P60HL- 17269-04 0024 National heart and blood vessel
research and demonstration center - Section of
experimental cardiovascular surgery -Core facility
P60HL-1 7269-04 0026 National heart and blood vessel
research and demonstration center - Dynamics of ischemic
heart disease (human, dog)
P60HL-1 7269-04 0027 National heart and blood vessel
research and demonstration center - Non-invasive
evaluation of cardiac function-lschemic heart disease
(human, dog)
ROlHL-17372-03 Adenine nucleotide maintenance in the
ischemic heart (rats)
ROlHL-1 7376-04 Analysis of Z bands in heart by optical
diffraction (mammals)
ROlHL-1 7459-03 Myocardial ischemia (dogs)
P50HL-1 7646-04 Study of ischemic heart disease
P50HL-1 7646-04 0002 Study of ischemic heart disease -
Core data management
P50HL-17646-04 0003 Study of ischemic heart disease -
Core pathology facility (human, dogs)
P50HL-1 7646-04 0004 Study of ischemic heart disease -
Core experimental animal laboratories
P50HL-17646-04 0005 Study of ischemic heart disease -
Biochemical markers and mediators of myocardial ischemic
injury
P50HL-1764604 0007 Study of ischemic heart disease -
Prediction of myocardial ischemic injury by analysis of
plasma CPK isoenzymes
P50HL- 17646-04 0009 Study of ischemic heart disease -
Regional metabolic derangements indicating ischemia
(rabbit, dog, human)
P50HL-17646-04 0012 Study of ischemic heart disease ■
Role of microcirculation in progression of myocardial
ischemic injury (rat)
P50HL-17646-04 0013 Study of ischemic heart disease -
Maintenance of myocardial vascular integrity after
revascularization (dogs)
P50HL-17646-04 0014 Study of Ischemic heart disease -
Progression of ischemic injury in conscious dogs (also
rabbits)
P50HL1 7646-04 0016 Study of ischemic heart disease ■
Humoral factors in ischemic heart rhythm, mechanical
performance (dog, rabbit)
P50HL- 17646-04 0017 Study of ischemic heart disease -
Dysrhythmia associated with acute myocardial infarction
(human, cat)
P50HL-1 7648-04 Study of ischemic heart disease
P50HL- 17648-04 0004 Study of ischemic heart disease -
Radionuclide imaging studies (human, pig)
P50HL-1 7648-04 0011 Study of ischemic heart disease -
Surgical treatment for acute myocardial ischemia (human,
dogs)
P50HL-17648-04 0012 Study of ischemic heart disease -
Retrograde coronary venous perfusion-Acute myocardial
ischemia
P50HL-17648-04 0020 Study of ischemic heart disease -
Core pathology laboratory-lschemic heart disease (human,
animal)
P50HL-17648-04 0021 Study of ischemic heart disease -
Biventricular contractile responses to acute myocardial
infarction (mammals)
P50HL-17648-04 0023 Study of ischemic heart disease -
Chemical mediators of inflammation in acute myocardial
infarction (mammals)
P50HL-17648-04 0025 Study of ischemic heart disease -
Destruction and repair of cardiac muscle cell constituents
(rat)
P50HL-17648-04 0027 Study of ischemic heart disease -
Phospholipid metabolism following cardiac injury and
repair (rat)
P50HL-17648-04 0031 Study of ischemic heart disease -
Ultrastructural consequences of myocardial ischemia (rat)
P50HL-17651-04 Ischemic heart disease specialized center
of research
P50HL-17651-04 0002 Ischemic heart disease specialized
center of research - Reduction of myocardial ishemic injury
by pharmacologic agents (human, dog)
P50HL-17651-04 0015 Ischemic heart disease specialized
center of research - Peripheral circulation in acute
myocardial ischemia and infarction (human)
' P50HL-17651-04 0016 Ischemic heart disease specialized
center of research - Retroperfusion of coronary venus
circulation with therapeutic agents (dogs)
' P50HL-17651-04 0022 Ischemic heart disease specialized
center of research - Electrophysiology -Mechanism and
pharmacology of arrhythmias (human, dog)
' P50HL-17651-04 0032 Ischemic heart disease specialized
center of research - Cardiovascular surgery core (human,
dogs)
P50HL-17651-04 0034
center of research -
P50HL-17651-04 0035
center of research -
biophysics
• P50HL-1765104 0036
center of research -
Ischemic heart disease specialized
Core facilities-Data management
Ischemic heart disease specialized
Core facilities-Biomedical engineering.
Ischemic heart disease specialized
Core facilities-Cardiovascular
pathology (human, dog)
P50HL-17651-04 0037 Ischemic heart disease specialized
center of research - Measurement of coronary venous
outflow by thermodilution (human)
P50HL-17651-04 0038 Ischemic heart disease specialized
center of research - Cardiothermography (human, dog)
P50HL-1 7651-04 0041 Ischemic heart disease specialized
center of research - Biochemical indices of ischemic injury
(guinea pig)
P50HL-17651-04 0043 Ischemic heart disease specialized
center of research - Gradual reperfusion following acute
coronary occlusion (dog)
P50HL-17651-04 0046 Ischemic heart disease specialized
center of research - Clinical core-Physiological
changes/biochemical effects of myocardial ischemia
P50HL-17651-04 0048 Ischemic heart disease specialized
center of research - Non-invasive detection of ischemic
heart disease
P50HL- 176 55-04 0001 Study of ischemic heart disease -
Intravenous nitroglycerin -Ventricular function and infarct
size (human, dog)
P50HL-17655-04 0003 Study of ischemic heart disease -
Cardiopulmonary resuscitation (human, dog)
P50HL-17655-04 0006 Study of ischemic heart disease -
Evaluation of coronary artery bypass graft surgery (human)
P50HL-17655-04 0011 Study of ischemic heart disease -
Core facility-Cardiovascular nuclear medicine (human, dog)
P50HL- 176 55-04 0012 Study of ischemic heart disease -
DATA management
P50HL17655-04 0014 Study of ischemic heart disease -
Blood flow and gas tension in myocardial Ischemia and
infarction (dog, monkey)
P50HL-17665-04 Study of ischemic heart disease
P50HL-17665-04 0001 Study of ischemic heart disease -
Reduction of acute anterior myocardial infarction-
Mechanical circulatory assist
P50HL-17665-04 0002 Study of ischemic heart disease -
Reducing acute anterior myocardial Infarction -Beta
adrenergic blockade (human)
P50HL-17665-04 0003 Study of ischemic heart disease -
Quantitation of injury-Acute myocardial infarction
complicated by shock (human)
P50HL-17665-04 0005 Study of ischemic heart disease -
Evaluation of zone of jeopardized myocardium in patients
with angina pectoris
P50HL-17665-04 0008 Study of Ischemic heart disease -
Core laboratory-CPK isoenzyme measurement and
myocardial necrosis evaluation
P50HL-17665-04 0012 Study of Ischemic heart disease -
Myocardial ischemia-Cardiovascular performance in the
conscious baboon and dog
P50HL-17665-04 0020 Study of ischemic heart disease -
Ischemic injury to myocardium during measured states of
ischemia (human)
' P50HL-17665-04 0021 Study of ischemic heart disease -
Identification, prevention -Myocardial ischemia in
cardiopulmonary bypass (dog)
P50HL-17665-04 0022 Study of ischemic heart disease -
Effect of coronary revascularization on left ventricular
function (human)
P50HL- 17665-04 0026 Study of ischemic heart disease -
Anesthesia -Myocardial ischemia and hemodynamics in
coronary disease (human)
P50HL-17665-04 0027 Study of ischemic heart disease -
Positron imaging of regional myocardial perfusion (human,
dog)
P50HL-17665-04 0028 Study of ischemic heart disease - J
Pathologic and biochemical studies of ischemic i
myocardium (human, dog)
P50HL- 17665-04 0029 Study of ischemic heart disease -
Myocardial protein synthesis and degradation in low oxygen
states (rabbit, dog)
P50HL-17665-04 0030 Study of ischemic heart disease ■
Data management
P50HL- 17667-04 0012 Study of ischemic heart disease -
Biochemistry of normal and ischemic heart -Glycolysis (rats)
P50HL-17667-04 0018 Study of ischemic heart disease -
Arrhythmias in ischemic heart disease (human)
P50HL-1 7667-04 0019 Study of ischemic heart disease -
Assessment of long-term results of coronary artery bypass i
grafting (human) I
P50HL-17667-04 0022 Study of ischemic heart disease - I
Preventing myocardial injury In surgery using |
cardiopulmonary bypass (human, rat)
P50HL-17667-04 0031 Study of ischemic heart disease -
Pathophysiology in ischemic heart disease (dog, cat, rabbit,
monkey)
' P50HL- 17667-04 0045 Study of ischemic heart disease -
Pathology of myocardial ischemic necrosis (human)
P50HL- 17669-04 Ischemic heart disease center (SCOR)
' P50HL-17669-04 0006 Ischemic heart disease center
(SCOR) - Studies of hypoxic, acidotic and ischemic cardiac
muscle (dogs)
' P50HL-1 7669-04 0007 Ischemic heart disease center
(SCOR) - Relationship between myocardial depression and
compliance (dogs, cats)
' P50HL-17669-04 0008 Ischemic heart disease center
(SCOR) - Segmental ventricular dysfunction during stress-
induced ischemia (dog, human)
P50HL-17669-04 0009 Ischemic heart disease center
(SCOR) - Infarct volume-99Tc stannous pyrophosphate
myocardial scintigrams (dogs, human)
' P50HL-1 7669-04 0011 Ischemic heart disease center
(SCOR) - Lysosomal function and lysosomal enzymes In
normal and ischemic heart (rabbit)
* P50HL- 17669-04 0012 Ischemic heart disease center
(SCOR) - Circulatory assistance (human, dog)
* P50HL- 17669-04 0013 Ischemic heart disease center
(SCOR) - Exercise in patients with ischemic heart disease
' P50HL-17669-04 0022 Ischemic heart disease center
(SCOR) - Pathological studies of human and experimental
Ischemic heart disease
P50HL- 17669-04 0023 Ischemic heart disease center
(SCOR) - Patients with acute myocardial infarction and
myocardial ischemia (human)
P50HL-17670-04 Study of ischemic heart disease
* P50HL-17670-04 0006 Study of ischemic heart disease -
Assessment of coronary artery hemodynamics and
myocardial blood flow (human)
P50HL-17670-04 0008 Study of ischemic heart disease -
Surgical treatment of cardiac rhythm disorders (human,
dogs)
* P50HL-17670-04 0009 Study of ischemic heart disease -
Surgical treatment of localized left ventricular dyssynergy
(human, dogs)
* P50HL-1 7670-04 0011 Study of ischemic heart disease •
Pharmacology of ischemic myocardium (dogs)
* P50HL-17670-04 0014 Study of ischemic heart disease -
Real time ultrasound imaging in ischemic heart disease
(human, dog)
* P50HL-17670-04 0020 Study of ischemic heart disease -
Radionuclide evaluation of coronary artery disease (human,
dog)
P50HL-17670-04 0021 Study of ischemic heart disease -
Enzymatic evaluation of acute myocardial infarction (dogs)
* P50HL-17670-04 0022 Study of ischemic heart disease -
Myocardial metabolism in hypoxia and recover (rabbit,
toad, dog)
* P50HL-17670-04 0023 Study of ischemic heart disease -
Energy metabolism in acute myocardial ischemic injury
(dogs)
I P50HL-17682-04 Study of ischemic heart disease
* P50HL-17682-04 0001 Study of ischemic heart disease -
Studies in acute and chronic ischemic heart disease
(human)
* P50HL-17682-04 0005 Study of ischemic heart disease -
Regional myocardial perfusion deficits and segmental
contraction disorders in man
P50HL-17682-04 0007 Study of Ischemic heart disease -
Mechanisms of hypoxemia in myocardial infarction (human)
* P50HL-17682-04 0008 Study of ischemic heart disease -
Clinical core unit
P50HL-1 7682-04 0010 Study of ischemic heart disease -
Core clinical enzyme laboratory (human, mice, dogs, rats)
P50HL-17682-04 0011 Study of ischemic heart disease -
Nuclear medicine core unit (human, dogs, rabbits, mice)
P50HL-1 7682-04 0012 Study of ischemic heart disease •
Pathology core laboratory (human)
(contd)
*Excludes routine methodokigy OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for Investigator's name and grant number.
HEA
PSOHL'17682'04 0013 Study of Ischsmic heail disease
Chronic ischemic heart disease-Myocardial tuncdon and
metabolism (dogs, swine)
PSOHL 1768? 04 0014 Study ol ischemic heart disease
Myocaidial ischemia Instiumentation and technique (dogs.
batHwns)
P50HL 17682 04 OOIS Study ot ischemic heart disease
Acute myocardial ischemia and inlarction and their
reversibility (dogs, baboons)
P50HL 1 768204 0016 Study of ischemic heart disease
Endurance exercise^ Prevention and rehabilitation in
ischemic heart disease (pig)
P50HL 1768204 0018 Study ot ischemic heart disease
Biochemistry of ischemia-Heart cell and organ culture
(mice. rats, cattle)
PSOHL' 17682-04 0020 Study of ischemic heart disease -
Nucleotide and nucleoside metabolism in ischemic
myocardium
P50HL 17682 04 0021 Study of ischemic heart disease
Prostaglandin biosynthesis in blood vessels from ischemic
myocardium (rat. sheep)
P50HL- 17682-04 0023 Study of ischemic heart disease
Core cell and organ culture laboratory (mice)
P50HL- 17682-04 0024 Study of ischemic heart disease
Phosphorylation of cardiac contractile proteins during
ischemia (rat, guinea pig)
' ROlHL-17736-04 Metabolic change during cardiac
ischemia (rats, dogs)
' ROIHLI 7809-04 Effects of exercise on the coronary
vasculature (rat. dog)
' ROlHL-l 7895-04 Myocardial function and metabolism
following ischemia (rats)
ROlHl-18024-03 Regional myocardial flow and function
relationships (dogs)
' ROIHL- 18206-04 Regulation of metabolism in oxygen
deficient hearts (rats)
■ ROIHL- 182 58-04 Regulation of protein degradation in
heart (rats)
' ROlHL-18288-04 Intraoperative protection of the
myocardium (dogs, rats)
ROlHL-18454-03 Maximal exercise testing in
hyperlipidemic children
* ROlHL-18460-01 Effects of prolonged hypoperfusion on the
myocardium (rabbits)
* ROlHL-18631-03 Ultrastructural correlates of myocardial
ischemia (rats, swine)
POlHL-18646-03 0008 Studies basic to heart
transplantation - Immunophysiology and early detection of
rejection (dogs)
* ROlHL-18647-03 Ischemic myocardial injury in cultured
heart cells (rats)
ROlHL-18705-03 Regulation of plasma triglyceride
metabolism (rats)
* POlHL-18708-03 0009 Oxygen, energy and contractility in
cardiac tissue - Regulation of oxygen utilization of cardiac
tissue (rats, rabbits)
ROlHL-18793-03 Clinical-pathologic studies of sudden
cardiac death (human)
* ROlHL-18795-04 Ischemic arrhythmias-Effect of
autonomic tone (dogs, rats, guinea pigs)
* ROlHL-18796-04 Experimental cardiac arrhythmias (dogs)
I ROlHL-18798-04 Nervous and ionic factors in sudden
cardiac death
Nervous and ionic factors in
Potassium loss during myocardial
ROlHL-18798-04 0001
sudden cardiac death
ischemia (rabbits)
ROlHL-18798-04 0002
sudden cardiac death
Nervous and ionic factors in
Electron microprobe, ultrastructure
analysis of ischemic myocardium (dog, rabbit)
ROlHL-18800-04 Prospective study of resuscitated sudden
death victims (human)
ROlHL-18805-04 0003 Sudden cardiac death and the
onset of myocardial infarction - Prediction from clinical and
laboratory assessments (human)
ROlHL-19000-03 Irreversible myocardial injury (rats)
ROlHL-19030-03 Tissue protection during circulatory
interruption (dogs)
ROlHL-19072-03 Modification of tissue injury in
myocardial infarction (dogs, human)
ROlHL-19089-03 Diastolic properties of the left ventricle
(human, dogs)
ROlHL-19127-03
imaging (rats)
ROlHL-19 135-04
blood flow (dogs)
ROlHL-19148-03
function (dog, rat)
ROlHL-19181-02 Regulation of heart cAMP-dependent
protein kinase (rodents)
ROlHL-19182-03 Surgical aspects of myocardial
hypertrophy (dogs)
ROlHL-19232-03 ECHO changes in wall motion with
myocardial ischemia
ROlHL-19289-03 Assessment of infusion methods for
myocardial mapping (dogs)
ROlHL-19370-03 Coronary capillary exchange-The effects
of ischemia (dogs, sheep)
ROlHL-19374-03 Pharmacology of kinins in cardiovascular
disease (rats, rabbits)
ROlHL-19398-03 Regional conduction abnormalities and
arrhythmias (dogs)
Synthesis of molecules for myocardial
Heterogeneity of regional myocardial
Myocardial organelle lipid structure and
751
ROIHI 19414 03 Protection of myocardium during cardiac
suigery (dogs, cats, human)
ROIHL 19451 03 0001 Functional characteristics ot the
left heart Ventricular performance using epicardial
radiopaque markers (human)
ROIHL 19451 03 0003 runctional characteristics of the
left heart Left ventricular segmental contraction (human,
dogs)
R01HL1953703 Detection of myocardial injury with
ultrasound (dogs)
ROIHL 19673-03 Surgical aspects of shock and hypoxia
(dogs, monkeys, rats)
Coronary pharmacoangiography
Pharmacologic studies on the ischemic
Vasodilators in experimental myocardial
Surgically induced myocardial edema
ROIHL-19675-02
ROIHL 19782 02
heart (dogs)
R01HL1993702
infarction (dogs)
ROlHL-20080-02
(dogs)
ROlHL-20163-02 Competitive coronary flow in native and
graft vessels (dog)
ROlHL-20225 02 Cardiac bypass and coronary collateral
physiology (dogs)
ROlHL-202 53-02 Effects of exercise on the heart and its
blood supply (dogs)
ROlHL-20283-02 Maintenance of cellular integrity in
ischemic hearts (cats)
ROlHL-20286-02 Interventions to improve cardiac function
in ischemia (dogs)
R01HL-20308-02 Regulation of myocardial acylcarnitine
transport (rats)
ROlHL-20476-03 Effects of diabetes on cardiac
performance (rat)
ROlHL-20484-03 Effects of diabetes on cardiac function
and metabolism (rats)
' ROlHL-20597-02 Electrophysiologic correlates of
myocardial ischemia (human, dogs, rabbits)
' ROlHL-20598-03 The coronary vascular response to
ischemia (dogs, pigs)
' ROlHL-20648-01 Physical factors and coronary flow (dogs)
ROlHL-20658-01 Myocardial energy transport -Creative
kinase (human, cattle, dog)
' ROlHL-20720-02 Myocardial protection during
cardiopulmonary bypass (dogs)
' ROlHL-20827-02 Effects of hypertrophy on the coronary
circulation (dogs)
ROlHL-20872-02 Multidimensional echo imaging of the
ischemic heart
ROlHL-20895-03 0005 Cineangiographic studies of
cardiovascular system - Computerized axial tomography-
Cardiac wall motion and infarction (dogs)
* ROlHL-20895-03 0006 Cineangiographic studies of
cardiovascular system - Cardiomyopathy -Hemodynamic,
radiologic, morphologic abnormalities (dog, rabbit)
P50HL21006-02 0005 Specialized center of research in
arteriosclerosis - Regional myocardial perfusion in patient
with coronary artery disease (also dogs)
ROlHL-21 187-01 Potassium, norepinephrine, and coronary
arterial tone (dogs)
* ROlHL-21209-02 Alterations of metabolism in ischemic
myocardium (swine)
* R23HL-2 12 62-02 Sodium-calcium interactions in
mammalian myocardium (rabbits, cats)
* ROlHL-21283-02 Simulation studies of the ECG in acute
ischemia (and human)
* ROlHL-21381-02 Amino acid metabolism in normal and
hypoxic myocardium (rabbits)
R23HL-21393-01 Cardiac adaptation to aging and stress
(rats)
* ROlHL-214 18-02 Experimental myocardial infarction (rats)
R23HL-21434-02 Intrinsic control of coronary blood flow by
chemicals (guinea pigs)
* ROlHL-21452-02 Pulmonary capillary filtration in
myocardial ishemia (dogs)
* ROlHL-21482-01
diabetes (rats)
* ROlHL-21570-01
energetics (cats)
* ROlHL-21589-01
ischemic heart
* ROlHL-21654-01 Autonomic determinants of arrhythmia
due to ischemia (cats)
* ROlHL-21657-01 Regional nonischemic myocardial
hypoxia (dogs)
ROlHL-2 16 84-02 0001 Radionuclide infarct sizing and
therapy evaluation - Evaluating preservation of ischemic
myocardium by radioisotope methods (dog)
* ROlHL-21684-02 0002 Radionuclide infarct sizing and
therapy evaluation - Evaluating myocardial imaging agents
in global and regional ischemia (rabbits)
ROlHL-21684-02 0004 Radionuclide infarct sizing and
therapy evaluation - Image analysis-Kinetics of infarction,
ventricular function (human, animal)
ROlHL-21684-02 0005 Radionuclide infarct sizing and
therapy evaluation - Clinical evaluation of radioisotope
imaging methods for quantifying infarct size
ROlHL-21690-02 Sequential multinuclide study of acute
infarction (human, dogs)
ROlHL-21697-01 Myocardium infarct sizing by 82Rb
emission tomography (dogs, human)
'* ROlHL-21706-02 Nuclear magnetic resonance and
myocardial ischemia (rats)
Cardiac function and metabolism in
The mechanical basis of myocardial
Radiographic contrast toxicity in
HIA
ROIHL 21/0/01 Quantification of infarct iiit by emitsion
tomography (human, dogs)
ROIHI 21/1001 Elertrocardiographic methods ol
quantifying infarct si/e (human, dogs)
ROIHL 21/19 01 Computed cardiac lomogrsphy in Infarct
sizing (dogs, human)
ROIHL 21/50 02 Electrocardiographic quantification of
infarct size (dogs, human)
R0IHL21/5I 02 Thallium and antimyosin in ischemia and
infarction
Thallium and antimyosin in
In Vitro models of ischemia and
Thallium and antimyosin in
Canine models of ischemia and
Thallium and antimyosin in
Human studies-Ischemia and
R01HL2175I 02 0001
ischemia and infarction
infarction (rats, mice)
R01HL21751 02 0002
ischemia and infarction
infarction
R01HL2175102 0003
ischemia and infarction
infarction
ROlHL-21786-01 Long term effects ol myocardial
protection (dogs, rats)
ROIHL 21793 02 Functional infarct size by gated
radioangiography (human, dogs)
ROlHL-21872-01 Myocardial perfusion in the hypertrophied
heart (dogs)
ROIHL 21969-01 Prevention of myocardial hypoxia during
by-pass (rats, mice, squirrels)
R23HL 21973-01 Catecholamine metabolism and the heart
(human, guinea pigs)
R23HL-22004-01 Imaging and ECG studies in acute and
chronic IHD (human)
ROlHL-22005-01 Intermittent retroperfusion of ischemic
myocardium (dogs)
ROlHL-22064-02 Glycogen metabolism in anoxic diabetic
myocardium (rats)
ROlHL-22080-01 Phospliorus NMR studies on cardiac
tissue (rats, rabbits)
ROlHL-22098-01 Is postoperative infarction due to
reperfusion injury? (human, dogs)
ROlHL-22135-01 Control of calcium fluxes across cardiac
membranes (dogs, rabbits, guinea pigs)
ROlHL-22 152-02 Ventricular dysfunction and cardiac
surgery (dogs)
ROlHL-22215-01 Effects of exercise-training in ischemic
heart disease (human)
ROlHL-22281-01 Microprobe analysis and metabolite
levels of ischemic mycardium (dogs)
ROlHL-22290-01 Cardiac energy metabolism and protein
synthesis (mice)
ROlHL-22315-01 Intraoperative cardiac oxygen supply-
demand (dogs, rabbits, rats)
ROlHL-22470-01 Liposome myocardial uptake in infarct
and ischemia (dogs, rats, mice)
ROlHL-22538-01 Myosin as a multi-enzyme complex (dogs,
rabbits)
R23HL-22575-01 Factors modifying cardiac digoxin effects
and content (dogs, cats)
POlHL-22619-01 Cellular mechanisms of heart failure
POlHL-22619-01 0003 Cellular mechanisms of heart
failure - Digitalis induced inotropy in myocardial ischemia
heart failure (animals)
P01HL-22e 19-01 0004 Cellular mechanisms of heart
failure - Mechanism of action of Na, K-ATPase (sheep,
cattle)
POlHL-22619-01 0006 Cellular mechanisms of heart
failure - Phosphorylation of contractile proteins in cardiac
muscle contraction (dogs, rabb
POlHL-22619-01 0008 Cellular mechanisms of heart
failure - Molecular mechanisms and differential contractile
responsiveness in VSM (dogs)
POlHL-22619-01 0009 Cellular mechanisms of heart
failure - Sarcoplasmic reticulum in cardiac, skeletal and
smooth muscle (rabbits, dogs)
POlHL-22619-01 0010 Cellular mechanisms of heart
failure - Mitochondria in heart and smooth muscle (rabbits,
rats, dogs)
POlHL-22619-01 0011 Cellular mechanisms of heart
failure - Reaction of lipoproteins and apolipoproteins with
lipoprotein lipase (cattle)
POlHL-22619-01 9001 Cellular mechanisms of heart
failure - Experimental pathological models core
' ROlHL-22732-01 Central organization of cardiac afferent
nerves (cats, monkeys)
ROlHL-22759-01 Regional myocardial blood flow during
hypothermia (dogs)
' ROlHL-22813-01 Palmitylcarnitine inhibition of ion pumps
in ischemia (dogs)
ROlHL-22815-01 Regional myocardial function after
revascularization (dogs)
' ROlHL-22828-01 Adenosine and catecholamine interaction
in the heart (rats)
' ROlHL-22917-01 Microvascular pressures in the intact
beating heart (rabbits)
' ROlHL-22982-01 Multicenter postcoronary risk
stratification program (human)
> ROlHL-23071-01
(dog, human)
■ ROlHL-23 138-01
embryo)
* ROlHL-23140-01
Electrophysiology of lethal arrhythmias
Myocardial ischemia (dogs, rats, chick
Determinants of irreversible ischemic
injuiy in heart (dog, rat)
(contd)
'Excludes routine methodotogy OR covers only general prajects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojeds describing specific research aspects.
See Appendix for investigator's name and grant number.
HEA
252
HEA
ROlHL-23142-01 Mechanisms of membrane injury in
myocardial ischemia (dog)
ROlHL-2315301 Mechanisms of altered CA20 transport in
ischemic heart (dog, rabbit)
ROlHL-23161-01 Biology of myocardial ischemia
ROlHL-23161-01 0001 Biology of myocardial ischemia -
Mitochondrial lipid metabolism and cardiac ischemia (rat,
dog)
R01HL'23I61-01 0002 Biology of myocardial ischemia -
Palmitylcarnitine inhibition of ion pumps in myocardial
ischemia (dog, sheep)
ROIHL'23161'01 0003 Biology of myocardial ischemia -
Phosphorylase coupling to myocardial sarcoplasmic
reticulum (dog)
ROIHL'2316101 0004 Biology of myocardial ischemia ■
Structure of myofibrils and membranes in early ischemia
(dogs, rabbit, rodents)
R01HL'23iei-01 0005 Biology of myocardial ischemia -
Localization of complement in myocardial infarction (dog)
ROlHL-23166-01 Pathology of mitochondria In Ischemic
myocardium (rats, cattle)
ROlHL-23171-01 Coronary collateral circulation in
myocardial ischemia (dog, pig, rat, human)
ROlHL-23587-01
(guinea pigs)
ROlHL-23599-01
disorders (dogs)
ROlHL-23624-01 Effect of drugs on ischemic cardiac cells
(dogs, guinea pigs, pigs)
ROlHL-23653-01 Protection of the ischemic myocardium
(dogs)
ROlHL-23970-01 Mechanisms and control of sudden
cardiac death (human, dog)
ROlHL-23982-01 Control of coronary flow by carbon
dioxide tension (dogs)
NOlHV-4291107 ECG center for prevention of coronary
heart disease (human)
NOlHV-62960-00 Techniques to protect ischemic
myocardium and minimize infant size (human)
NOlHV-72941-02 Therapy to protect ischemic myocardium-
Clinical tests
' NOlHV-72942-02
Clinical tests
' NOlHV-72979-01
Data Center
Phosphorylation of myocardial protein
Mechanisms of ischemic rhythm
Therapy to protect ischemic myocardium-
Therapy to protect ischemic myocardium-
HEART DISORDERS, CORONARY FIBROSIS
P01HL-046e4-18 0011 Cardiovascular and lung dynamics
• Detection of abnormal segments of the human ventricle
by measure of asynergy
P01HL-04e64-18 0012 Cardiovascular and lung dynamics
- Quantitative single plane left ventricular angiography
(human)
•* POlHL-14388-07 0218 Regulation of the circulation in
pathological states - Regional myocardial dyskinesis -Cause
assessment and reduction (dogs)
** P01HL14388-07 0219 Regulation of the circulation in
pathological states - Myocardial ischemia and Infarction In
animals (dogs)
P50HL-17651-04 0038 Ischemic heart disease specialized
center of research • Cardiothermography (human, dog)
ROlHL-18805-04 0007 Sudden cardiac death and the
onset of myocardial infarction - Analysis of pathologic
factors involved in sudden death (human)
HEART DISORDERS, CORONARY OCCLUSIONS
AND THROMBOSIS
" POlHL-06285-18 0154 Cardiovascular-respiratory
physiology and biochemistry - Function and viability of
critically ischemic myocardium (dogs)
POlHL-06308-18 0029 Mechanisms and therapy of
circulatory disease - Characterization of the patient with
recurrent ventricular arrhythmias
POlHL-06308-18 0038 Mechanisms and therapy of
circulatory disease • Electrophysiology of ventricuair
arrhythmias associated with ischemia (dogs)
** POlHL-06312-17 0016 Surgical cardiology - Effect of
hydralazine on infarct size following coronary occlusion
(human)
** POlHL-06312-17 0025 Surgical cardiology - Effect of
denervation on arrhythmias and function with coronary
occlusion (dogs)
POlHL-06312-17 0043 Surgical cardiology - The
cylindrical ventricular assist device (dogs)
POlHL-08682-15 0018 Regulation of the cardiovascular
system - Functional implications of cardiac afferent nerves
(dogs)
ROlHL-09315-15 Coronary insufficiency and myocardial
revascularization (human, dogs)
** P01HL10539-12 0070 Pathophysiology of circulation -
Effects of hypertension on myocardial blood flow after
coronary occlusion (dogs)
ROlHL-1 1876-11 Regional myocardial blood flow and
metabolism (dogs, swine)
** ROlHL-12611-10 Basic and clinical studies of the STT
deflection (human, dogs)
** POlHL-12738-10 0069 Physiologic pharmacology and its
clinical applications - Blood rheology in coronary heart
disease (dogs)
POlHL-1273810 0081
clinical applications
Regulation of the circulation in
Experimental myocardial infarction
Physiologic pharmacology and its
Ultrastructural and electrophysiologic
alteration of myocardium (human, dogs)
POlHL-12738-10 0123 Physiologic pharmacology and its
clinical applications - Ventricular assistance and
preservation (human, dogs)
POlHL-12738-10 0124 Physiologic pharmacology and its
clinical applications - Counterpulsation on myocardial
ischemia measured by carbon dioxide tension (dogs)
POlHL-12738-10 0132 Physiologic pharmacology and its
clinical applications - Coronary occlusions and arrhythmias
(dogs)
ROlHL-13036-08 Coronary thrombosis-Effects on
myocardium and in vivo detection (dogs, monkeys)
POIHL- 134 80-09 0032 Cardiac electrophysiology - Cardiac
activation sequence (dogs)
P50HL 14147-08 0007 Specialized center of research in
thrombosis - Radioactive tracers in recognition of
intravascular coagulation (human, dogs)
POlHL-14388-07 0219 Regulation of the circulation in
pathological states - Myocardial ischemia and infarction in
animals (dogs)
P01HL14388-07 0221
pathological states
(dogs)
POlHL-15194-07 0017 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation and
effects of arteriographic lesions on flow (human)
POlHL-15194-07 0018 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation,
metabolic demand and vasodilatory reserve (human, dogs)
ROlHL-15512-06 Drug treatment of stenosing primate
atherosclerosis (rabbits, monkeys)
ROlHL-15562-05 Regulation of skeletal muscle blood flow
(dogs)
' ROlHL-15581-06 Coronary flow studies of partially
obstructed vessels (dogs)
ROlHL-155 11-04 Sympathetic afferent activity of cardiac
origin (dogs, monkeys)
ROlHL-16657-06 Innervation of coronary arteries and heart
(rats)
' POlHL-169 10-05 0002 Regulation of the peripheral
circulation - Coronary circulation (dogs)
P60HL-17269-04 0007 National heart and blood vessel
research and demonstration center ■ Correlative studies of
experimental myocardial ischemia (dog)
P60HL-17269-04 0023 National heart and blood vessel
research and demonstration center - Cardiovascular
pharmacology-Ischemia, shock and heart failure (dog, cat,
rat)
P50HL-17646-04 0013 Study of ischemic heart disease -
Maintenance of myocardial vascular integrity after
revascularization (dogs)
P50HL-17646-04 0014 Study of ischemic heart disease ■
Progression of ischemic injury in conscious dogs (also
rabbits)
P50HL-17648-04 0013 Study of ischemic heart disease -
Fate of bypassed and bypassing vessels (dogs)
P50HL-17648-04 0020 Study of ischemic heart disease -
Core pathology laboratory-lschemic heart disease (human,
animal)
P50HL-17648-04 0023 Study of ischemic heart disease -
Chemical mediators of inflammation in acute myocardial
infarction (mammals)
P50HL-17651-04 0002 Ischemic heart disease specialized
center of research - Reduction of myocardial ishemic injury
by pharmacologic agents (human, dog)
P50HL-17651-04 0022 Ischemic heart disease specialized
center of research - Electrophysiology-Mechanism and
pharmacology of arrhythmias (human, dog)
* P50HL-17651-04 0043 Ischemic heart disease specialized
center of research - Gradual reperfuslon following acute
coronary occlusion (dog)
P50HL-17651-04 0045 Ischemic heart disease specialized
center of research - Peripheral vascular studies-
Pharmacology (dogs, human)
* P50HL17665-04 0012 Study of ischemic heart disease -
Myocardial ischemia -Cardiovascular performance in the
conscious baboon and dog
P50HL-1 7665-04 0032 Study of ischemic heart disease -
Myocardial infarct sizing-lmmunoassay for cardiac myosin
light chains (dogs)
P50HL-17669-04 0006 Ischemic heart disease center
(SCOR) - Studies of hypoxic, acidotic and ischemic cardiac
muscle (dogs)
P50HL- 176 70-04 0009 Study of ischemic heart disease -
Surgical treatment of localized left ventricular dyssynergy
(human, dogs)
* P50HL-17670-04 0020 Study of ischemic heart disease -
Radionuclide evaluation of coronary artery disease (human,
dog)
P50HL-17670-04 0021 Study of ischemic heart disease -
Enzymatic evaluation of acute myocardial infarction (dogs)
P50HL-17682-04 0013 Study of ischemic heart disease -
Chronic ischemic heart disease-Myocardial function and
metabolism (dogs, swine)
P50HL-17682-04 0015 Study of ischemic heart disease -
Acute myocardial ischemia and infarction and their
reversibility (dogs, baboons)
P50HL- 176 82-04 0021 Study of ischemic heart disease -
Prostaglandin biosynthesis in blood vessels from ischemic
myocardium (rat, sheep)
ROlHL-17907-04 Brain regulation of cardiac arrhythmia
(pigs, cats, rats)
ROlHL-18468-03 The distribution of flow in the
myocardium (dog, pig)
ROlHL-18492-03 Measurement of regional coronary flow
reserve (human, dogs)
ROlHL-18793-03 Clinical-pathologic studies of sudden
cardiac death (human)
ROlHL-18796-04 Experimental cardiac arrhythmias (dogs)
ROlHL-18798-04 0003 Nervous and ionic factors In
sudden cardiac death - Left stellectomy In the prevention
of sudden death (dogs)
ROlHL-18805-04 0007 Sudden cardiac death and the
onset of myocardial infarction - Analysis of pathologic
factors involved in sudden death (human)
ROIHL- 19045-03 Electrophysiology of cardiac automaticlty
(human, dogs)
ROlHL-19182-03 Surgical aspects of myocardial
hypertrophy (dogs)
ROlHL-19343-03 Behavioral Influences on cardiac
contractility (monkeys)
ROlHL-19374-03 Pharmacology of kinins In cardiovascular
disease (rats, rabbits)
ROlHL-19451-03 0003 Functional characteristics of the
left heart - Left ventricular segmental contraction (human,
dogs)
ROlHL-19537-03 Detection of myocardial injury with
ultrasound (dogs)
ROlHL-19680-01 Cardiac correlates of behavioral stress in
animals (dog)
R01HL-20ie3-02 Competitive coronary flow in native and
graft vessels (dog)
ROIHL 20179-02
among women
ROlHL-20199-02
in the rat
R01HL-2028e-02 Interventions to Improve cardiac function
in ischemia (dogs)
ROlHL-20394-03 Complement activation by heart
subcellular membranes (human, dog)
ROlHL-20598-03 The coronary vascular response to
ischemia (dogs, pigs)
Cineangiographic studies of
Densitometry in coronary stenosis
Epidemiology of sudden cardiac death
Drug-induced alterations in infarct size
ROlHL-20895-03 0003
cardiovascular system
(human)
ROlHL-20895-03 0004
cardiovascular system
Cineangiographic studies of
Cineangiography -Coronary lesions
and ventricular function (human)
** ROlHL-20895-03 0008 Cineangiographic studies of
cardiovascular system - Intercoronary anastomotic
circulation -Stenosis and occlusion (dogs)
R23HL-21151-02 Ischemic myocardium-Delivery of blood
flow and drugs (dogs)
ROlHL-21239-02 Isolation and mechanism of action of
thromboxane A2 (human, rabbits)
R23HL-21298-02 Coronary vasomotion (dogs, pigs)
ROlHL-21533-02 Platelet inhibitor drug in coronary surgery
(human)
ROlHL-21719-01 Computed cardiac tomography In Infarct
sizing (dogs, human)
ROlHL-21751-02 0002 Thallium and antimyosin in
ischemia and infarction - Canine models of ischemia and
infarction
ROlHL-21872-01 Myocardial perfusion In the hypertrophied
heart (dogs)
ROlHL-22445-01 Platelet inhibitors -Effect on coronary
bypass grafts (dogs)
** ROlHL-22862-01 CNS-medlated effects of antiarrhythmic
drugs (dogs)
** ROlHL-22952-01 Validation of quantitative coronary
arteriography (dogs)
ROlHL-23071-01 Electrophysiology of lethal arrhythmias
(dog, human)
ROlHL-23140-01 Determinants of irreversible ischemic
injury in heart (dog, rat)
ROlHL-23161-01 0005 Biology of myocardial ischemia -
Localization of complement in myocardial infarction (dog)
ROlHL-23171-01 Coronary collateral circulation in
myocardial ischemia (dog, pig, rat, human)
ROlHL-23206-01 Repetitive exercise and cardiac
enlargement (dogs)
ROlHL-23599-01 Mechanisms of ischemic rhythm
disorders (dogs)
ROlHL-23970-01 Mechanisms and control of sudden
cardiac death (human, dog)
HEART DISORDERS, ENDOCARDIAL
FIBROELASTOSIS
ROlHL-18848-03 Etiology and development of congenital
heart disease (dogs, cats)
HEART DISORDERS, ENDOCARDITIS BACTERIAL
POlHL-06314-17 0060 Immunologic mechanisms in
cardiovascular disease - Strept antigens and infections In
cardiovascular complications (human, animals)
** POlHL-06370-17 0016 Cardiopulmonary and renal
pathology research center - Endocarditis with pulmonary
artery catheters (dogs)
** ROlHL-17751-03 Experimental endocarditis (rabbits)
** ROlHL-19818-02 Endocarditis on prosthetic heart valves
(rabbits, human)
** ROlHL-22888-01 Prosthetic valve endocarditis-Etiology
and therapy (dogs)
(contd)
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
^^
HEA
HEART DISORDERS, ENDOMYOCARDIAL
FIBROSIS
ROIHL 1?99; 07 Myocirdial defects induced by potassium
depletion (human, rats, cats)
ROIHL 2178601 Lonj term etiects ot myocardial
protection (do|s. lats)
HEART DISORDERS, HEART ARREST
ROIHL 07605 lb Congenital heart disease leseaich
program (human, dogs)
POIHL'10436'13 0008 A multidisciplinary study of
congenital heart disease Physiologic consequences of
chronic hypoxemia (human)
POIHL 11310 12 0053 Mechanisms ot cardiovascular
disease Ventricular pressure-volume alter cardipulmonary
bypass (dogs)
POIHL 12738 10 0094 Physiologic pharmacology and its
clinical applications Ventricular function and structure
(human, dogs)
ROIHL 13454 08 Behavioral stress and cardiomyopathy
(monkeys, cats)
R01HL16292-05 0002 Surgery and non-obstructive
coronary insufficiency Effects of hypothermia during
cardiopulmonary bypass (dogs)
ROIHL 16412-04 Release ot nucleosides from the ischemic
heart (human, dogs)
P50HL- 17648-04 0023 Study of ischemic heart disease ■
Chemical mediators of inflammation in acute myocardial
infarction (mammals)
P50HL-17651-04 0032 Ischemic heart disease specialized
center of research ■ Cardiovascular surgery core (human.
dogs)
•* P50HL17655-04 0003 Study of Ischemic heart disease
Cardiopulmonary resuscitation (human, dog)
P50HL-17665-04 0020 Study of ischemic heart disease
Ischemic injury to myocardium during measured states of
ischemia (human)
P50HL- 17665-04 0021 Study of ischemic heart disease
Identification, prevention -Myocardial ischemia in
cardiopulmonary bypass (dog)
P50HL17667-04 0022 Study of ischemic heart disease
Preventing myocardial injury in surgery using
cardiopulmonary bypass (human, rat)
ROlHL-18288-04 Intraoperative protection of the
myocardium (dogs, rats)
•* ROlHL-18590-03 Cerebral blood flow after cardiac arrest
(dogs, monkeys)
** ROlHL-18769-04
(human)
ROlHL-18794-04
(human)
*• ROlHL-19030-03
interruption (dogs)
ROlHL-19148-03 Myocardial organelle lipid structure and
function (dog, rat)
ROlHL-20077-02 External cardiac stimulation with
.microwave radiation (dogs)
ROlHL-22080-01 Phosphorus NMR studies on cardiac
tissue (rats, rabbits)
HEART DISORDERS, HEART ENLARGEMENT
SEE ALSO CONGENITAL ABNORMALITIES, HEART DEFECTS,
ASYMMETRIC SEPTAL HYPERTROPHY
SEE ALSO HEART DISORDERS, HEART FAILURE, CONGESTIVE
ROlHL-03290-22 Controls of cardiac and vascular smooth
muscles (cats, rats, dogs)
ROlHL-07605-16 Congenital heart disease research
program (human, dogs)
** ROlHL-09172-15 Protein and RNA synthesis in heart
muscle (rats)
ROlHL-10384-13 Blood flow and nucleotide metabolism
(animals)
** POlHL-11310-12 0090 Mechanisms of cardiovascular
disease - Clinicopathological cardiovascular correlation
(human, animals)
POlHL-12738-10 0080 Physiologic pharmacology and its
clinical applications - Electrophysiology of cardiac muscle
in the mitral valve (monkeys)
R01HL12997-07 Myocardial defects induced by potassium
depletion (human, rats, cats)
** ROlHL-15837-06 Renin and cardiac hypertrophy in
hypertension (rats)
** ROlHL-16637-04 Development and regression of cardiac
hypertrophy (rats)
R01HL17376-04 Analysis of I bands in heart by optical
diffraction (mammals)
P50HL-17648-04 0025 Study of ischemic heart disease -
Destruction and repair of cardiac muscle cell constituents
(rat)
P50HL17648-04 0027 Study of ischemic heart disease -
Phospholipid metabolism following cardiac injury and
repair (rat)
ROlHL-18629-04 Influence of aging and hypertension on
the myocardium (rats)
ROlHL-19182-03 Surgical aspects of myocardial
hypertrophy (dogs)
** ROlHL-19246-03 Regression of cardiac hypertrophy-
Myocardial and renal (human)
ROlHL-19648-03 Myocardial protein degradation (dogs.
rabbits)
ROlHL-20426-03 Myocardial function in diabetes mellitus
(dog, rat)
Studies in survivors of lethal arrhythmias
Prospective studies of conduction disease
Tissue protection during circulatory
2S3
M POIHL 20984 02 Cellular mechanisms in cardiac
hypertrophy
•* POIHI 20984 02 0001 Cellular mechanisms in cardiac
hypertrophy Contractile proteins in cardiac hypertrophy
(rabbits, calves)
•* POIHL 20984 02 0002 Cellular mechanisms in cardiac
hypertrophy Thermodynamic, fluorescence, chemical
modilication ot hypertiophied heart myosin
•* POIHL 20984-02 0003 Cellular mechanisms in cardiac
hypertrophy Fast kinetics of myosin ATPase from normal
and hypertrophied heart (rabbits)
** POIHL 20984 02 0004 Cellular mechanisms in cardiac
hypertrophy Myofibril accumulation in cardiac and
vascular muscle cells in hypertrophy
** POIHL 20984 02 0005 Cellular mechanisms in cardiac
hypertrophy Neurohumoral receptors in cardiac growth
and compensatory hypertrophy (animals)
" POlHL-20984-02 0006 Cellular mechanisms In cardiac
hypertrophy Earty biochemical aspects ot cardiac
hypertrophy (rats)
** POIHL 20984 02 9001 Cellular mechanisms in cardiac
hypertrophy Animal models and preparation of contractile
proteins
" POlHL-20984-02 9002 Cellular mechanisms in cardiac
hypertrophy The heart in organ culture
** R23HL-2142101 Myocardial and vascular contractility and
cyclic nucleotides (cattle, rats)
ROlHL-21471-02 Structure-function studies on actin and
myosin (human, protozoa, rabbits, cattle)
ROlHL-22039-02 Ion transport in cardiac muscle (dogs,
rodents, cattle)
** POlHL-2261901 0006 Cellular mechanisms of heart
failure Phosphorylation of contractile proteins in cardiac
muscle contraction (dogs, rabb
** POlHL-226 19-01 0007 Cellular mechanisms of heart
failure - Regulation of contractile protein levels in heart
muscle (rats)
ROlHL-22651-01 Control of protein metabolism in heart
muscle
** ROIHL 22664-01 Regulation of myocardial cell growth
(rats, guinea pigs)
** ROlHL-22859-01 Effect of carbon monoxide on the
developing heart (rats)
ROlHL-22985-01 Properties and assembly of Z-disk
proteins (human, other species)
** ROlHL-23025-01 Adaptive heart growth in neonates and
adults (rats)
** ROlHL-23206-01 Repetitive exercise and cardiac
enlargement (dogs)
** ROlHL-23626-01 A study of the regulation of myocardial
hypertrophy (rats)
HEART DISORDERS, HEART ENLARGEMENT,
VENTRICULAR HYPERTROPHY
** ROlHL-01015-27 Hypertension and left ventricular
hypertrophy (dogs)
POlHL-06285-18 0143 Cardiovascular-respiratory
physiology and biochemistry - Myocardial ischemia (human,
dogs, lambs)
POlHL-06285-18 0153 Cardiovascular-respiratory
physiology and biochemistry - Myocardial mechanics and
pharmacology in isolated papillary muscle (animals)
** POlHL-06285-18 0178 Cardiovascular-respiratory
physiology and biochemistry - Biochemical regulation of
hypertrophy (rats, rabbits)
POlHL-06285-18 0179 Cardiovascular-respiratory
physiology and biochemistry - Regulation of myocardial cell
growth (rats, chick embryo)
POlHL-063 12-17 0048 Surgical cardiology - Use of an
adjustable pulmonary artery band (dogs)
POlHL-06835-17 0030 Cardiovascular disease - Synthesis
and pharmacology of angiotensin antagonists (rats, cats)
** POlHL-06835-17 0037 Cardiovascular disease - Cardiac
hypertrophy in spontaneously hypertensive rat
POlHL-06835-17 0038 Cardiovascular disease - Effect of
chronic administration of angiotensin antagonist (rats)
POlHL-06835-17 0039 Cardiovascular disease -
Reversibility of vascular changes in renal hypertension
(rats)
POlHL-06835-17 0041 Cardiovascular disease - Cardiac
performance in rats with renal hypertension
** POlHL-06835-17 0042 Cardiovascular disease ■
Myocardial hypertrophy due to renal hypertension (rats)
** POlHL-06835-17 0057 Cardiovascular disease - Studies
on cardiac hypertrophy
** POlHL-06835-17 0060 Cardiovascular disease -
Ventricular performance experimental models of arterial
hypertension (rats, dogs)
R01HL-07139-17 Cardiodynamics and metabolism of
congestive failure (human, dogs)
** ROlHL-09562-14 Cardiac protein synthesis, overload,
alcohol and anoxia (guinea pigs)
POlHL-10436-13 0002 A multidisciplinary study of
congenital heart disease • Myocardial performance,
metabolism and ultrastructurc (human, cats, rats)
POlHL-1 13 10-12 0053 Mechanisms of cardiovascular
disease - Ventricular pressure-volume after cardipulmonary
bypass (dogs)
POlHL-1 13 10-12 0063 Mechanisms of cardiovascular
disease - Myocardial function, metabolism and cellular
integrity after heart surgery (dogs)
HfA
POIHI 11310 12 0080 Mechanism) of cardiovascular
disease Metabolism of the hypertrophied myocardium
(human)
POIHL 11310 12 0093 Mechanisms of cardiovascular
disease Multiple dipole electrocardiogram proied (human,
dogs)
ROIHL 11876 II Regional myocardial blood flow and
metabolism (dogs, swine)
POIHL 12373 10 0001 Cardiopulmonary physiology and
pathophysiology Mechanics of myocardial contraction
(dogs. rats, swine)
POIHL 12373 10 0002 Cardiopulmonary physiology and
pathophysiology Determinants of performance of the
whole heart (dogs)
POIHL 12373 10 0003 Cardiopulmonary physiology and
pathophysiology Myocardial function in man
POIHL 12738 10 0094 Physiologic pharmacology and its
clinical applications Ventricular function and structure
(human, dogs)
ROIHL 13636 08 Effects of pharmacologic agents on heart
metabolism (human, rodents)
' ROIHL 1363907 Factors altering the course of myocardial
dysfunction (cats)
P50HL 14187 07 0005 Pulmonary SCOR-^Chemical
mediators in pulmonary vascular responses Pulmonary
hypertension and cardiac function (dogs, human)
POIHL 14388-07 0213 Regulation of the circulation in
pathological states Regulation of the heart and peripheral
circulation in heart failure
POIHL 14388-07 0214 Regulation of the circulation in
pathological states Deformation pattern and stress
analysis of the left ventricle
POIHL 14388-07 0215 Regulation of the circulation in
pathological states - Left ventricle model in
pathophysiologic states
' P01HL14388-07 0216 Regulation of the circulation in
pathological states Development and regression of
ventricular hypertrophy (cats, rats)
* POlHL-14388-07 0219 Regulation of the circulation in
pathological states - Myocardial ischemia and infarction in
animals (dogs)
* ROlHL-14545-06 Mechanics of compensatory ventricular
hypertrophy (dogs)
ROlHL-14651-05 Mechanical behavior of left ventricle
(dogs, rats)
* ROlHL-14717-06 Hemodynamics and heart structure-
Ventricular overload (dogs)
ROlHL-14903-07 A new index of cardiac contractility
(human, dogs, baboons)
POlHL-14985-07 0010 Adaptation to hypoxia - Pulmonary
mast cell (animals)
ROlHL-15047-06 Digital computer analysis of the
electrocardiogram (human)
POlHL-15194-07 0001 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation, venous
drainage and collateral flow (human, dogs)
* ROIHL- 15498-06 Effects of physical training on heart
(rats)
ROlHL-15888-05 Comparative stereology of the
myocardium (birds, mammals)
* ROlHt-15983-04 Regional myocardial blood flow (dogs)
ROlHL-16076-06 Electrophysiology of fibrillation and
defibrillation (human)
POlHL-16117-05 0005 Ion movements and membranes in
cardiovascular control - Properties of isolated cell
membranes (rabbits, cats)
* ROlHL-16420-02
heart
ROlHL-16656-06
(dogs)
'* R01HL-16706-04
failure (dogs, rabbits)
'* P60HL-17269-04 0020 National heart and blood vessel
research and demonstration center - Nucleic acid and
protein metabolism in growth and development of heart
(rat)
'* P60HL- 17269-04 0021 National heart and blood vessel
research and demonstration center - Growth and
development of heart-Ultrastructure (dog, guinea pig, rat.
cat)
** ROlHL-17592-03 Activation and contraction heat in
enlarged hearts (rabbits)
•* ROlHL-17631-05 Experimental congestive heart failure and
hypertrophy (cats)
P50HL-17667-04 0045 Study of ischemic heart disease -
Pathology of myocardial ischemic necrosis (human)
P50HL-1 7670-04 0005 Study of ischemic heart disease -
Quantitative assessment of the vectorcardiogram (human)
P50HL- 17682-04 0001 Study of ischemic heart disease -
Studies in acute and chronic ischemic heart disease
(human)
P50HL- 17682-04 0012 Study of ischemic heart disease -
Pathology core laboratory (human)
P50HL-17682-04 0016 Study of ischemic heart disease -
Endurance exercise-Prevention and rehabilitation in
ischemic heart disease (pig)
** ROlHL-17931-04 Normalized body surface potential maps
(children)
** ROlHL-18024-03 Regional myocardial flow and function
relationships (dogs)
** R01HL-18087-03 Development and regression of cardiac
hypertrophy (rats, rabbits)
(contd)
Effect of training-detraining on the rat
Left ventricular function in exercise
Excitation-contraction coupling and heart
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
**0riented significantly to above subject.
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
mA
HEA
254
HEA
Renin
ROlHL-18288-04 Intraoperative protection of the
myocardium (dogs, rats)
P50HL-18323-04 0012 SCOR hypertension center ■
as a risk factor (human)
ROlHL-18338-04 Computer feedback study of cardiac
muscle mechanics (rats)
R01HL-184S6-03 Cardiovascular follow-up of hypertensive
adolescents
ROlHL-1846803 The distribution of flow in the
myocardium (dog, pig)
RClHL-18527-03 Subcellular response of heart to
functional overload (hamsters, rats)
ROlHL-18824-03 Mechanisms of heart failure in
myopathic hamster
ROlHL-18850-03 Classification code for Frank orthogonal
ECG
R01HL18933-03 Energy output and efficiency of left
ventricle (dog)
R01HL19182-03 Surgical aspects of myocardial
hypertrophy (dogs)
ROlHL-19394-03 Biochemistry and regulation of taurine In
the heart (rats, guinea pigs, cats)
ROlHL-19425-03 Cardiac function in hypertrophy (dog)
R01HL1946103 Myocardial energetics in hypertrophy and
heart failure (rabbits)
ROlHL'19486-03 Dipole moment measurement of cardiac
mass (rabbits, pigs)
R01HL-20087-02 Developmental processes in pulmonary
hypertension (rats)
ROlHL-20190-02 Pathogenesis of cardiac hypertrophy
(dogs)
ROlHL-20211-02
mice)
POlHL-20552-02
cardiac hypertrophy
POlHL-20552-02 0001
cardiac hypertrophy
hypertrophy (rats)
POlHL-20552-02 0002
cardiac hypertrophy
Role of taurine in the heart (dogs, rats.
The development and regression of
The development and regression of
Biochemical events in cardiac
The development and regression of
Effect of treatment on the
hypertrophied left ventricle (rats)
POlHL-2055202 0003 The development and regression of
cardiac hypertrophy - Muscle mechanics of the
hypertrophied left ventricle (rats)
POlHL-2055202 0004 The development and regression of
cardiac hypertrophy ■ Ventricular function in experimentally
Induced hypertrophy (hogs, sheep, baboons)
POlHL-20552-02 0010 The development and regression of
cardiac hypertrophy - Energy metabolism in the
hypertrophied heart animals
POlHL-20552-02 9001 The development and regression of
cardiac hypertrophy - Core A-Pathology
P01HL-205S2-02 9002 The development and regression of
cardiac hypertrophy - Core B-Blomathematics
POlHL-2055202 9003 The development and regression of
cardiac hypertrophy ■ Core D-Amino acids analysis
ROlHL-20572-02 Hemodynamic relations to metabolism in
hypertension
ROlHL-20572-02 0001 Hemodynamic relations to
metabolism in hypertension - Hemodynamic and myocardial
functional studies in the SHR (rat)
ROlHL-2057202 0003 Hemodynamic relations to
metabolism in hypertension - Cardiac output and organ
blood flow In hypertension (rats)
ROlHL-20572-02 0007 Hemodynamic relations to
metabolism in hypertension ■ Drug effects on cardiac
function and hypertropy (rats)
POlHL-20592-02 Cell biology of cardiac and skeletal
muscle
POlHL-20592-02 0010 Cell biology of cardiac and
skeletal muscle - Mitochondrial genesis during myocardial
cell hypertrophy and hyperplasia (rats)
R01HL-20e78-02 Cardiovascular adaptation to stress in
disease states (dogs)
ROlHL-20749-01 Developing heart-Biophysical aspects
(sheep)
ROlHL'20768-02 Mechanisms of circulatory regulation in
heart failure (guinea pigs)
ROlHL-20827-02 Effects of hypertrophy on the coronary
circulation (dogs)
ROlHL-20883-02 Fiber geometry in hypertrophy and
cardiomyopathy (human)
R23HL-21167-02 The electrophysiology of cardiac
hypertrophy (rats)
ROlHL-21182-02 Active tension and shortening in cardiac
hypertrophy (rabbits)
R23HL-2 1197-02 Right ventricular contraction and
relaxation (dogs)
R23HL-21234-02
(rabbits)
R23HL-2 1292-01 Human ventricular activation-Patterns
and mechanisms (human)
ROlHL-2 1690-02 Sequential multinuclide study of acute
infarction (human, dogs)
ROlHL-21820-01 Regulatory role of myosin In cardiac
hypertrophy (dogs)
ROlHL-21850-01 Calcium transport in the hypertrophied
myocardium (rats, animals)
ROlHL-21872-01 Myocardial perfusion in the hypertrophied
heart (dogs)
ROlHL-21993-01 Hypertensive hypertrophy-Effects of
cardiac mechanics (rats)
The regulation of cardiac hypertrophy
** ROlHL-22008-01 Left ventrivular calcium content and
contractility (rats)
ROlHL-22101-02 Hormone-substrate Interaction in diabetic
myocyte (dogs, rats)
ROlHL-221 52-02 Ventricular dysfunction and cardiac
surgery (dogs)
** ROlHL-22269-01 Excitation-contraction coupling in
enlarged hearts (rabbits)
** POlHL-22619-01 0009 Cellular mechanisms of heart
failure - Sarcoplasmic reticulum in cardiac, skeletal and
smooth muscle (rabbits, dogs)
** ROlHL-22828-01 Adenosine and catecholamine Interaction
in the heart (rats)
ROlHL-23206-01 Repetitive exercise and cardiac
enlargement (dogs)
NOlHV-429 11-07 ECG center for prevention of coronary
heart disease (human)
HEART DISORDERS, HEART FAILURE
** POlHL-06285-18 0155 Cardiovascular-respiratory
physiology and biochemistry - Therapeutic alterations,
contractile state in heart failure
ROlHL-07776-15 Sudden death and cardiac arrhythmias
(human, dogs, cats)
ROlHL-09562-14 Cardiac protein synthesis, overload,
alcohol and anoxia (guinea pigs)
M ROlHL-10612-13 Humoral factors in heart failure and
hypertension
POlHL-1 1307-12 0003 Biophysical studies in pediatric
cardiology - Cellular biophysics (animals)
POlHL-1 13 10-12 0056 Mechanisms of cardiovascular
disease - Cardiac output response to blood pressure
reduction in infants (human)
POlHL-11310-12 0080 Mechanisms of cardiovascular
disease - Metabolism of the hypertrophied myocardium
(human)
POlHL-1 1678-11 0020 Cardiovascular dynamics and their
control - Circulatory and pulmonary fluid dynamics during
pulmonary edema
ROlHL-1190611 Comparative study of heart function
(cats, rats, hedgehogs, squirrels)
** POlHL-12738-10 0071 Physiologic pharmacology and Its
clinical applications - lABP patient management In
ventricular power failure (human)
POlHL-12738-10 0092 Physiologic pharmacology and Its
clinical applications - Subendocardial Ischemia following
open heart surgery (human)
*♦ POlHL-12738-10 0098 Physiologic pharmacology and its
clinical applications - Skeletal muscle support of the
chronically failing heart (dogs)
POlHL-12738-10 0123 Physiologic pharmacology and Its
clinical applications - Ventricular assistance and
preservation (human, dogs)
ROlHL-12990-09 Control of antidiuretic hormone secretion
and metabolism (dogs, rats, rabbits)
** ROlHL-12997-07 Myocardial defects induced by potassium
depletion (human, rats, cats)
** POlHL-13330-08 0059 Mechanical circulatory support -
Physiologic evaluation of circulatory assistance (cattle)
ROlHL-137 15-08 Myocardial adenyl cyclase (rats)
POlHL-13737-07 0007 Assisted circulation -
Determination of cardiac status by use of balloon pump
(dogs)
POlHL-13737-07 0009 Assisted circulation - Analytical
models
** POlHL-13737-07 0029 Assisted circulation - Chronic left
ventricular failure (human)
POlHL-13737-07 0032 Assisted circulation - The dynamic
aortic patch (human, dogs)
POlHL-13738-08 0001 Cardiac assist devices and
artificial hearts - Cardiac assist devices (human, sheep)
POlHL-13738-08 0002 Cardiac assist devices and
artificial hearts - Total replacement with artificial heart
(calves, sheep, ponies)
POlHL-13738-08 0003 Cardiac assist devices and
artificial hearts - Pathophysiological effects of the artificial
heart (calves)
** P50HL-14187-07 0005 Pulmonarv SCOR-Chemical
mediators In pulmonary vascular responses - Pulmonary
hypertension and cardiac function (dogs, human)
POlHL-14388-07 0172 Regulation of the circulation in
pathological states - cAMP-dependent protein kinase from
heart and vascular smooth muscle (guinea pigs)
POlHL-14388-07 0179 Regulation of the circulation In
pathological states - Cultured muscle cells and their cross-
Innervation in vitro (rats, sheep)
POIHL- 143 88-07 0183 Regulation of the circulation in
pathological states - Vasopressin in cardiovascular
regulation (dogs, rats)
POIHL- 143 88-07 0185 Regulation of the circulation in
pathological states - Reflex control of venous tone (human.
ROlHL-15676-06 The role of occult myocardial failure in
human shock (human, dogs)
rabbits, dogs)
POlHL-14388-07 0211
pathological states -
(rats)
POlHL-14388-07 0213
pathological states -
Regulation of the circulation in
Choline acetyltransferase activity
Regulation of the circulation in
Regulation of the heart and peripheral
circulation in heart failure
ROlHL-14545-06 Mechanics of compensatory ventricular
hypertrophy (dogs)
ROlHL-147 17-06 Hemodynamics and heart structure-
Ventricular overload (dogs)
ROlHL-15740-06
(rats)
ROlHL-15758-06
(dogs)
ROIHL- 15983-04
ROlHL-16233-05
In vitro studies on heart cell function
Catecholamine release in the heart
Intrarenal regulation of sodium
Excitation-contraction coupling and heart
Regional myocardial blood flow (dogs)
Molecular cardiology of MDP-lnduced left
ventricular failure (dogs)
ROlHL-16606-11 Contraction in heart and other striated
muscles (frogs)
ROlHL-16658-05
reabsorption
ROlHL-16706-04
failure (dogs, rabbits)
P60HL-172e9-04 0018 National heart and blood vessel
research and demonstration center - Mitochondria and
energetics (rabbits, dogs)
P60HL- 17269-04 0029 National heart and blood vessel
research and demonstration center - Clinical application of
circulatory assistance (human)
ROlHL-17403-03 Metabolic control of cardiac output
(dogs)
ROlHL-17555-05 Distribution and metabolism of labeled
digitaloids (dogs, guinea pigs)
P50HL 17648-04 0011 Study of ischemic heart disease -
Surgical treatment for acute myocardial ischemia (human,
dogs)
P50HL-17651-04 0015 Ischemic heart disease specialized
center of research - Peripheral circulation In acute
myocardial ischemia and infarction (human)
P50HL-17e55-04 0001 Study of ischemic heart disease -
Intravenous nitroglycerin-Ventricular function and infarct
size (human, dog)
P50HL- 17665-04 0012 Study of ischemic heart disease -
Myocardial ischemia -Cardiovascular performance in the
conscious baboon and dog •
P50HL- 17667-04 0038 Study of Ischemic heart disease -
Clinical core unit
P50HL-17e69-04 0007 Ischemic heart disease center
(SCOR) - Relationship between myocardial depression and
compliance (dogs, cats)
ROlHL-17954-03 Narcotics and the circulation (human,
dogs, pigs, monkeys)
ROlHL-18338-04 Computer feedback study of cardiac
muscle mechanics (rats)
ROlHL-18527-03 Subcellular response of heart to
functional overload (hamsters, rats)
ROlHL-18749-03 Ventricular mechanics in the overloaded
heart (dogs)
ROlHL-18824-03 Mechanisms of heart failure in
myopathic hamster
ROIHL- 18848-03 Etiology and development of congenital
heart disease (dogs, cats)
R01HL-19044-03 Effect of drugs on development of
cardiac failure (cats)
ROlHL-19378-03 Relation of mitochondrial changes to
cardiac failure (dogs, rats)
ROlHL-19485-03 Calcium uptake by normal and failed
cardiac ATPase (dogs)
ROlHL-20476-03 Effects of diabetes on cardiac
performance (rat)
POlHL-20552-02 0010 The development and regression of
cardiac hypertrophy - Energy metabolism in the
hypertrophied heart animals
ROlHL-20630-03 Development of a pulsed Doppler velocity
detector (human, animals)
R01HL-207e8-02 Mechanisms of circulatory regulation in
heart failure (guinea pigs)
ROlHL-20803-02 Intra-aortic balloon pumping (dogs,
lambs, cats)
POlHL-20984-02 0001 Cellular mechanisms in cardiac
hypertrophy - Contractile proteins in cardiac hypertrophy
(rabbits, calves)
ROlHL-21038-01 Electrically induced cardiac EM-
histochemical changes (animals)
ROlHL-21239-02 Isolation and mechanism of action of
thromboxane A2 (human, rabbits)
R23HL-21421-01 Myocardial and vascular contractility and
cyclic nucleotides (cattle, rats)
ROlHL-21452-02 Pulmonary capillary filtration in
myocardial ishemia (dogs)
ROlHL-21493-02 Contractility in cardiac failure (hamsters)
ROlHL-21498-02 Pathophysiology of edema (rats, cats)
R23HL-21842-01 Control of sugar entry in normal and
diabetic heart (rats)
ROlHL-21846-01 Cardiac failure detection by radiography
and optics (monkeys)
ROlHL-2 1850-01 Calcium transport in the hypertrophied
myocardium (rats, animals)
ROlHL-21948-01 Capillary, tissue volume and lymph flow
in lung edema (sheep, cattle)
ROlHL-22008-01 Left ventrivular calcium content and
contractility (rats)
ROlHL-22039-02 Ion transport in cardiac muscle (dogs.
rodents, cattle)
ROlHL-22064-02 Glycogen metabolism in anoxic diabetic
myocardium (rats)
ROlHL-22080-01 Phosphorus NMR studies on cardiac
tissue (rats, rabbits)
ROlHL-22219-01 Prostacyclin and peroxides in blood and
membrane disease
(contd)
"Excludes routine mettndokjgy OR covers only general pmjects which preclude indexing at the specific level.
**OTieflted significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
HEA
R23HL-22S7501 Factors modifying ctnilK digoxin oltects
and content (dogs, cats)
■• POIHI 2261901 0002 Cellular mechanisms o( heart
lallure Structure of sodium, potassium adenosine
triphosphatase (lambs, dogs)
•• POIHL 22619 01 0006 Cellular mechanisms of heart
failure Phosphorylation of contractile proteins in cardiac
muscle contraction (dogs, labb
•* POIHL 22619 01 0009 Cellular mechanisms of heart
failure Sarcoplasmic reticulum in cardiac, skeletal and
smooth muscle (rabbits, dogs)
•• P01HL2261901 0010 Cellular mechanisms of heart
failure Mitochondria in heart and smooth muscle (rabbits,
rats, dogs)
•* POIHL 22619 01 9001 Cellular mechanisms of heart
failure Eipenmental pathological models core
** ROlHL-2275001 Oigoxin in heart failure with sinus
rhythm (human)
** NOlHV-53006 06 Evaluation of model VII left ventricular
assist device (human)
HEART DISORDERS, HEART FAILURE,
CONGESTIVE
SEE ALSO HEART DISORDERS. HEART ENLARGEMENT
ROIHL 02334-23 Micropuncture study of kidney function
(rats, animals)
•* ROlHL-02493-22 Kidney function in experimental heart
failure (dogs, rats)
P01HL06285-18 0145 Cardiovascular respiratoiy
physiology and biochemistry • Pulmonary, pleural and
systemic microcirculation (animals)
•* POlHL-0630818 0042 Mechanisms and therapy of
circulatory disease - Echocardiographic assessment of
arrhythmias-Myocardial tissue type (human, dogs)
** ROlHL-0713917 Cardiodynamics and metabolism of
congestive failure (human, dogs)
** R01HL0923413 Amino acids of contractile proteins of
failing hearts (dogs, hamsters)
R01HL0971113 Instantaneous blood flow in ascending
aorta (human, dogs)
** R01HL0992113 Mechanisms related to congestive heart
failure (dogs, human, rat)
R01HL1018213 Circulatory function and electrolytic
metabolism (dogs, human)
P01HL1043613 0008 A multidisciplinaiy study of
congenital heart disease ■ Physiologic consequences of
chronic hypoxemia (human)
** ROlHL-1061213 0021 Humoral factors in heart failure
and hypertension - The control of aldosterone secretion
(dogs)
P01HL11310-12 0091 Mechanisms of cardiovascular
disease ■ Noninvasive techniques in cardiovascular
diagnosis (human)
P01HL1167811 0027 Cardiovascular dynamics and their
control ■ Vasopressin and thirst in control of body fluid
volumes and osmolality (dogs)
R01HL1232210 Extrinsic factors influencing myocardial
performance (dogs, swine)
ROlHL-12997-07 Myocardial defects induced by potassium
depletion (human, rats, cats)
ROlHL-13426-09 Left ventricular bypass for myocardial
infarction (cattle, human)
ROIHL- 13427-09 Neural control of blood volume (monkeys.
dogs)
R01HL-13623-08 Atrial receptors (dogs)
RClHL-13636-08 Effects of pharmacologic agents on heart
metabolism (human, rodents)
** ROlHL-13639-07 Factors altering the course of myocardial
dysfunction (cats)
R01HL-13870-09 Control of myocardial sarcotubular
calcium stores (dogs)
ROlHL-14148-07 0008 The regional circulations ■ Renal
circulation in hypertensive patients (also dogs)
POlHL-14388-07 0221 Regulation of the circulation in
pathological states ■ Experimental myocardial infarction
(dogs)
** ROlHL-14461-08 Cardiac metabolism in heart failure
(rats)
ROlHL-14713-06 Hypothermia and the heart (bats, guinea
pigs)
R01HL16037-06 Molecular properties of cardiac
adrenergic receptors
P60HL-1 7269-04 0019 National heart and blood vessel
research and demonstration center - Sarcoplasmic
reticulum (dog, rabbit, hamster, cat)
P60HL-1 7269-04 0023 National heart and blood vessel
research and demonstration center ■ Cardiovascular
pharmacology-Ischemia, shock and heart failure (dog. cat,
rat)
P60HL-1 7269-04 0024 National heart and blood vessel
research and demonstration center - Section of
experimental cardiovascular surgery-Core facility
** ROlHL-17631-05 Experimental congestive heart failure and
hypertrophy (cats)
P50HL-17651-04 0046 Ischemic heart disease specialized
center of research - Clinical core-Physiological
changes/biochemical effects of myocardial ischemia
** P50HL-1 7665-04 0022 Study of ischemic heart disease
Effect of corona ly revascularization on left ventricular
function (human)
P50HL-17670-04 0009 Study of ischemic heart disease -
Surgical treatment of localized left ventricular dyssynergy
(human, dogs)
255
ROIHL 17796 04 Importanca of amlnosugarj In digitalis
activity (cats, rabbits)
'• ROIHL 1785303 Peripheral circulation in heart failure
(animals)
ROIHL 18204 03 Regional blood flow in viral myocarditis
(turkeys)
P50HL 18318 03 0010 Pathogenesis and complications of
hypertension Hemodynamics in mineralocorticoid and low
renin hypertension (human)
P50HL 1831803 0019 Pathogenesis and complications of
hypertension Renin angiotensin system in blood pressure
regulation (human, rat. dog)
ROIHL 1859902 Cardiovascular pharmacology of
lonophores (dogs)
** ROIHL 1860604 Pathogenesis and measurement of
pulmonary edema (human, rabbits, dogs)
•* R01HL1871804 Prostaglandin precursors and vascular
reactivity (dogs)
** R01HL18862-02 Thirst and its contribution to edema
(dogs)
ROIHL 18866-02 Microvascular flow, volume, and
reactivity (rats, cats)
** ROIHL 18873 02 Early radiologic diagnosis of cardiac
failure (monkey)
ROlHL-19044-03 Effect of drugs on development of
cardiac failure (cats)
*• ROIHL 19089-03 Diastolic properties of the left ventricle
(human, dogs)
ROIHL- 191 82-03 Surgical aspects of myocardial
hypertrophy (dogs)
ROlHL-19366-03 Renal Starting forces in experimental
conditions (rats, rabbits)
ROlHL-19394-03 Biochemistry and regulation of taurine in
the heart (rats, guinea pigs, cats)
ROlHL-19425-03 Cardiac function in hypertrophy (dog)
** ROlHL-19461-03 Myocardial energetics in hypertrophy and
heart failure (rabbits)
ROlHL-20426-03 Myocardial function in diabetes mellitus
(dog. rat)
ROlHL-20558-02 Cardiac electrophysiology-Effects of ions
and drugs
*• ROlHL-21052-01 Evaluation of a digitalis therapy advisor
** R23HL-2 1066-02 Angiotensin and prostaglandm control of
aldosterone (rats)
R23HL-21203-02 Effect of vasoactive agents on left-to-
right shunts (lambs)
ROlHL-21272-02 Sodium homeostasis and renal
prostaglandins (dogs)
ROlHL-21843-01 Ischemia, diabetes and the
microcirculation (rats. cats, hamsters)
ROlHL-22051-01 Role of angiotensin II in vasopressin
release (human)
** ROlHL-22594-01 Reflex control of the circulation in heart
failure (dogs)
M POlHL-22619-01 Cellular mechanisms of heart failure
** POlHL-226 19-01 0003 Cellular mechanisms of heart
failure - Digitalis induced inotropy in myocardial ischemia
heart failure (animals)
** POlHL-226 19-01 0007 Cellular mechanisms of heart
failure - Regulation of contractile protein levels in heart
muscle (rats)
ROlHL-22750-01 Digoxin in heart failure with sinus
rhythm (human)
R23HL-22882-01 Modulation by disease of effect of
furosemide in man
** R23HL-22959-01 Heart development in inherited
cardiomyopathy (hamsters)
** ROlHL-22977-01 Role of vasoconstrictor mechanisms in
heart failure (human, dogs)
** ROlHL-231 15-01 Regulation of active sodium transport
(frogs, rats)
HEART DISORDERS, MYOCARDIAL DISORDERS
SEE ALSO CONGENITAL ABNORMALITIES, HEART DEFECTS,
ASYMMETRIC SEPTAL HYPERTROPHY
SEE ALSO HEART DISORDERS, CORONARY, MYOCARDIAL
INFARCT
SEE ALSO HEART DISORDERS, CORONARY, MYOCARDIAL
ISCHEMIA AND HYPOXIA
SEE ALSO HEART DISORDERS, ENDOMYOCARDIAL FIBROSIS
POlHL-04664-18 0001 Cardiovascular and lung dynamics
- X-ray projection image videodensitometry (dogs)
ROlHL-05694-20 Functional pathology of cardiovascular
disease (human)
** ROlHL-05875-18 Pathologic metabolic and physiologic
studies of heart (human, dogs, cats)
ROlHL-05949-18 Biochemistry of muscle contraction (rats,
rabbits)
POlHL-06370-17 0014 Cardiopulmonary and renal
pathology research center ■ Quantitative morphology in
cardiac disease (human, rats, dogs)
ROlHL-09172-15 Protein and RNA synthesis in heart
muscle (rats)
*• R01HL-09234-13 Amino acids of contractile proteins of
failing hearts (dogs, hamsters)
** ROlHL-09562-14 Cardiac protein synthesis, overload,
alcohol and anoxia (guinea pigs)
** R01HL-099U-13 The myocardium in diabetes mellitus
(dogs, monkeys)
M POlHL-10539-12 Pathophysiology of circulation
** POlHL-10539-12 0068 Pathophysiology of circulation -
Acute and chronic cardiomyopathies (mice, dogs, hamsters,
human)
HEA
POIHL 11310 12 0053 Mechanumt of cardiovaicular
disease Ventricular pressure volume after cardipulmonary
bypass (dogs)
• POIHL 11310 1? 0080 Mechanltma of cardiovascular
disease Metabolism of the hypertrophied myocardium
(human)
• ROIHL 12997 07 Myocardial defects induced by potassium
depletion (human, rats, cats)
ROIHL 1303608 Coronary thrombosis Effects on
myocardium and in vivo detection (dogs, monkeys)
• POIHL 1310809 0013 Clinical heart transplantation
Cardiomyopathic lymphocyte responsiveness to cultured
endothelium
• ROIHL 1345408 Behavioral stress and cardiomyopathy
(monkeys, cats)
• POIHL 14388-07 0218 Regulation of the circulation in
pathological states Regional myocardial d/skinesis -Cause
assessment and reduction (dogs)
POIHL 14388-07 0219 Regulation of the circulation in
pathological states Myocardial ischemia and infarction in
animals (dogs)
ROlHL-14651-05 Mechanical behavior of left ventricle
(dogs, rats)
ROlHL-14713-06 Hypothermia and the heart (bats, guinea
pigs)
ROlHL-14717-06 Hemodynamics and heart structure-
Ventricular overtoad (dogs)
'* ROlHL-14938-06 Contractile proteins of heart muscle
(dogs, rabbits)
POIHL- 15194-07 0001 Pathophysiology of
cardiopulmonary dysfunction • Coronary circulation, venous
drainage and collateral flow (human, dogs)
POlHL-15194-07 0020 Pathophysiology of
cardiopulmonary dysfunction ■ Coronary circulation in
arteriographically normal arteries (human)
R01HL15522-06 Influence of mannifol on ischemia
cardiac muscle (dogs, cats, rats)
P60HL 17269-04 0033 National heart and blood vessel
research and demonstration center - Autoallergic response
in cardiomyopathy, atherosclerosis, rheumatic heart disease
ROlHL-17754-03 Pathogenesis and prevention of
hypertension sequelae (rats)
" ROlHL-18032-03 Development of normal and myopathic
mammalian heart (hamsters)
ROlHL-18456-03 Cardiovascular follow-up of hypertensive
adolescents
*♦ ROlHL-18527-03 Subcellular response of heart to
functional overload (hamsters, rats)
P01HL-18646-03 0008 Studies basic to heart
transplantation - Immunophysiology and eariy detection of
rejection (dogs)
** ROIHL- 18824-03 Mechanisms of heart failure in
myopathic hamster
ROlHL-19003-03 High precision densitometry of coronary
angiograms
ROlHL-19089-03 Diastolic properties of the left ventricle
(human, dogs)
ROlHL-19127-03 Synthesis of molecules for myocardial
imaging (rats)
ROlHL-19203-03 Surgical approach to congenital heart
diseases (dogs, primates)
ROlHL-19232-03 ECHO changes in wall motion with
myocardial ischemia
** ROlHL-20369-03 The effect of alcohol on the heart (rats)
** ROlHL-20401-03 Relationship of insulin to catechol
cardiomyopathy (rabbit, pig)
** ROlHL-20426-03 Myocardial function in diabetes mellitus
(dog. rat)
R01HL-20428-03 The juvenile diabetic heart (human)
** ROlHL-20754-02 Anesthetic-induced myocardial depression
(rabbits)
ROlHL-20883-02 Fiber geometry in hypertrophy and
cardiomyopathy (human)
ROlHL-21276-02 Development of 99-mTc myocardial
imaging agents
** R23HL-21327-02 Molecular mechanisms of chemical
myocardiopathies (rats)
** ROlHL-21482-01 Cardiac function and metabolism In
diabetes (rats)
ROlHL-21493-02 Contractility in cardiac failure (hamsters)
" ROlHL-22152-02 Ventricular dysfunction and cardiac
surgery (dogs)
" R01HL-22550-02 Genetic cardiomyopathies in salamanders
and hamsters
ROlHL-2275001 Digoxin in heart failure with sinus
rhythm (human)
** R23HL-22959-01 Heart development in inherited
cardiomyopathy (hamsters)
** ROlHL-23618-01 Substrate metabolism in isolated
myocytes in shock (dogs, rats, guinea pigs)
HEART DISORDERS, MYOCARDIAL DISORDERS,
HYPERTROPHIC MYOCARDIOPATHY
SEE ALSO CONGENITAL ABNORMALITIES, HEART DEFECTS.
ASYMMETRIC SEPTAL HYPERTROPHY
SEE ALSO HEART DISORDERS, HEART ENLARGEMENT,
VENTRICULAR HYPERTROPHY
POlHL-11310-12 0089 Mechanisms of cardiovascular
disease - Structure and function in myocardial contraction
(dogs)
** ROlHL-20895-03 0011 Cineangiographic studies of
cardiovascular system - Ventricular hypertrophy and
preoutflow contraction (human, dogs)
(contd)
'Excludes routine nethodokigy OR covers only general projects which preclude indexing at the specific level.
"Oiiented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
HEA
256
HEA
ROlHL-21970-01 Myofibrillar assembly and breakdown in
cardiac muscle (rats)
HEART DISORDERS, MYOCARDITIS
♦* P01HL10539-12 0068 Pathophysiology of circulation ■
Acute and chronic cardiomyopathies (mice, dogs, hamsters,
human)
** ROlHL-18204-03 Regional blood flow in viral myocarditis
(turkeys)
** ROlHL-18535-03 Epidemiology and course of viral
myopericardltis (human)
** R01HL-2104701 Studies of coxsackievirusinduced
myocarditis in mice
HEART DISORDERS, OUTPUT ABNORAUVLITIES
SEE ALSO HEART DISORDERS, HEART FAILURE
SEE ALSO HEART DISORDERS, VALVULAR
'* POlHL-06285-18 0131 Cardiovascularrespiratorv
physiology and biochemistry - Fetal heart development and
ventricular outflow obstruction (lambs)
POlHL-06285-18 0157 Cardiovascular-respiratory
physiology and biochemistry - Left ventricle outflow
impedance analysis (human)
P01HL07293-17 0051 Noninvasive cardiovascular
measurements - Physiologic evaluation of duplex scanner
(dogs)
P01HL0868215 0026 Regulation of the cardiovascular
system - Hypertenslon-HIgh renin vs low renin (dog)
POlHL-12738 10 0071 Physiologic pharmacology and its
clinical applications - lABP patient management in
ventricular power failure (human)
POlHL-1273810 0094 Physiologic pharmacology and its
clinical applications - Ventricular function and structure
(human, dogs)
POlHL-13480-09 0026 Cardiac electrophysiology ■ Neural
influences on cardiac electrophysiology and contraction
(dog, cat)
P50HL-14187-07 0005 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses - Pulmonary
hypertension and cardiac function (dogs, human)
ROlHL-14717-06 Hemodynamics and heart structure-
Ventricular overload (dogs)
ROlHL-16233-05 Molecular cardiology of MDP-induced left
ventricular failure (dogs)
ROIHL'18848'03 Etiology and development of congenital
heart disease (dogs, cats)
** P50HL- 19190-02 0008 Pulmonary SCOR-Pathophysiology,
management of IRDS ■ Hemodynamics and gas exchange-
Determinants of hypotension (human, infant)
HEART DISORDERS, PERICARDITIS
** ROlHL-18535-03 Epidemiology and course of viral
myopericardltis (human)
ROlHL-20597-02 Electrophysiologic correlates of
myocardial ischemia (human, dogs, rabbits)
HEART DISORDERS, RHEUMATIC HEART DISEASE
** ROlHL-01803-23 0019 Arteriosclerosis, glomerulonephritis,
rheumatic fever ■ Pathogenesis of rheumatic heart disease
(rabbit)
POlHL-06314-17 0060 Immunologic mechanisms in
cardiovascular disease - Strept antigens and infections in
cardiovascular complications (human, animals)
** P60HL-1 7269-04 0033 National heart and blood vessel
research and demonstration center - Autoallergic response
in cardiomyopathy, atherosclerosis, rheumatic heart disease
** ROlHL-19234-03 Streptococci and heart-Cell-mediated
cross-reaction (mice)
** ROlHL-19307-03 Problems in prevention of rheumatic
heart disease (human)
HEART DISORDERS, SUDDEN DEATH
ROlHL-03341-22 Epidemiology of atherosclerosis in Evans
Co Georgia
** ROlHL-05806-18 Analysis of antiarrhythmic agents (dogs,
rabbits)
** POlHL-06308-18 0010 Mechanisms and therapy of
circulatory disease - Ventricular arrhythmias during exercise
to CHD and myocardial ischemia (human)
** P01HL06308-18 0011 Mechanisms and therapy of
circulatory disease - Blood flow and electrical dysfunction
in ventricular arrhythmia (human)
** POlHL-06308-18 0037 Mechanisms and therapy of
circulatory disease - Electrophysiology, blood flow, and ANS
in ventricular fibrillation (dogs)
ROlHL-07047-16 Comparative study of cardiac conduction
system (human, birds, mammals)
ROlHL-07605-16 Congenital heart disease research
program (human, dogs)
** ROlHL-07776-15 Sudden death and cardiac arrhythmias
(human, dogs, cats)
M POlHL-08974-14 Natural and experimental atherosclerosis
** POlHL-08974-14 0005 Natural and experimental
atherosclerosis • Atherosclerosis, coronary heart disease
and sudden death (human)
** POIHLI 1310-12 0090 Mechanisms of cardiovascular
disease - Clinicopathological cardiovascular correlation
(human, animals)
** POlHL-1273810 0117 Physiologic pharmacology and its
clinical applications - Ventricular arrhythmias in ischemic
heart disease (human)
POlHL-13330-08 0059 Mechanical circulatory support
Physiologic evaluation of circulatory assistance (cattle)
Brain regulation of cardiac arrhythmia
Studies in survivors of lethal arrhythmias
Experimental cardiac arrhythmias (dogs)
Nervous and ionic factors in sudden
ROlHL-13454-08 Behavioral stress and cardiomyopathy
(monkeys, cats)
POlHL-13480-09 0026 Cardiac electrophysiology - t4eural
influences on cardiac electrophysiology and contraction
(dog, cat)
ROlHL-13974-07 Ventricular premature beats and sudden
coronary death (human)
ROlHL-15681-06 Coronary flow studies of partially
obstructed vessels (dogs)
ROlHL-16076-06 Electrophysiology of fibrillation and
defibrillation (human)
ROlHL-17532-04 Infarct size-ECG, angio, path, correlation
in dogs
P50HL17655-04 0006 Study of ischemic heart disease -
Evaluation of coronary artery bypass graft surgery (human)
P50HL 17667-04 0001 Study of ischemic heart disease -
Natural history of ischemic heart disease (human)
P50HL-17670-04 0012 Study of ischemic heart disease -
Epidemiology of sudden death (human)
ROlHL-17907-04
(pigs, cats, rats)
ROlHL-1876904
(human)
ROlHL-18776-04 Preventmn of acute and fatal
cardiovascular disease (human)
ROIHL 18783-04 Detection and control of ventricular
premature beats (human)
ROlHL-18793-03 Clinical-pathologic studies of sudden
cardiac death (human)
ROlHL-18794-04 Prospective studies of conduction disease
(human)
ROlHL-18796-04
ROlHL-1879804
cardiac death
ROlHL-18798-04 0003 Nervous and ionic factors in
sudden cardiac death - Left stellectomy in the prevention
of sudden death (dogs)
ROlHL-18800-04 Prospective study of resuscitated sudden
death victims (human)
ROlHL-1880504 Sudden cardiac death and the onset of
myocardial infarction
ROlHL-1880504 0001 Sudden cardiac death and the
onset of myocardial infarction - Predictive value of
maximum exercise stress testing (human)
ROlHL-18805-04 0003 Sudden cardiac death and the
onset of myocardial infarction - Prediction from clinical and
laboratory assessments (human)
ROlHL-18805-04 0004 Sudden cardiac death and the
onset of myocardial infarction - Sudden death survivors-
Clinical follow-up and therapy (human)
ROlHL-18805-04 0005 Sudden cardiac death and the
onset of myocardial infarction - Sudden death survivors-
Radionuclide studies (human)
ROlHL-18805-04 0007 Sudden cardiac death and the
onset of myocardial infarction - Analysis of pathologic
factors involved in sudden death (human)
ROlHL-18808-04 Prediction and prevention of sudden
cardiac death
R01HL18808-04 0001 Prediction and prevention of
sudden cardiac death - Prognostic significance of
premature ventricular contractions (human)
ROlHL-19182-03 Surgical aspects of myocardial
hypertrophy (dogs)
ROlHL-19398-03 Regional conduction abnormalities and
arrhythmias (dogs)
ROlHL-1945103 0003 Functional characteristics of the
left heart - Left ventricular segmental contraction (human,
dogs)
ROlHL-19680-01 Cardiac correlates of behavioral stress in
animals (dog)
ROlHL-19839-09 Factors in youth predisposing to chronic
diseases (former college students)
ROlHL-20179-02
among women
ROlHL-20238-02
(human)
ROlHL-21010-02
40,000 persons
R23HL-21298-02
ROlHL-2152701
(human)
ROlHL-21654-01 Autonomic determinants of arrhythmia
due to ischemia (cats)
ROlHL'21674-01 Development of automatic implanted
defibrillator (dogs, cattle)
R23HL-22004-01 Imaging and ECG studies in acute and
chronic IHD (human)
ROlHL-22135-01 Control of calcium fluxes across cardiac
membranes (dogs, rabbits, guinea pigs)
ROlHL-22862-01
drugs (dogs)
ROlHL-23071-01
(dog, human)
ROlHL-23078-01
death (human)
ROlHL-239 70-01
Epidemiology of sudden cardiac death
Prospective bundle branch block study
Glycemia, other traits and CV death in
Coronary vasomotion (dogs, pigs)
Prospective study of bundle branch block
CNS-mediated effects of antiarrhythmic
Electrophysiology of lethal arrhythmias
Psychosocial stress and sudden coronary
Mechanisms and control of sudden
cardiac death (human, dog)
HEART DISORDERS, VALVULAR
SEE ALSO HEART TRANSPLANTATION, VALVES
TRANSPLANTATION
POlHL-04664-18 0010 Cardiovascular and lung dynamics
- Lett ventricular dynamics (human)
ROlHL-05694-20 Functional pathology of cardiovascular
disease (human)
POlHL-06308-18 0012 Mechanisms and therapy of
circulatory disease - Echocardiographic evaluation of
hemodynamics of arrhythmia (human)
POlHL-06314-17 0060 Immunologic mechanisms in
cardiovascular disease - Strept antigens and infections in
cardiovascular complications (human, animals)
POlHL-06314-17 0061 Immunologic mechanisms in
cardiovascular disease - Role of viruses in cardiovascular
and renal disease (human, mice)
POlHL-07293-17 Noninvasive cardiovascular
measurements
POlHL-07293-17 0043 Non-invasive cardiovascular
measurements - ECHO-Doppler instrumentation for cardiac
measurements (human)
POlHL-07293-17 0045 Non-invasive cardiovascular
measurements - Cardiac scanner transducer position
locating systems (human)
POlHL-07293-17 0047 Non-invasive cardiovascular
measurements - Cardiac scanner system software
P01HL07293-17 0051 Non-invasive cardiovascular
measurements ■ Physiologic evaluation of duplex scanner
(dogs)
POlHL-07293-17 0052 Non-invasive cardiovascular
measurements - Clinical evaluation of the duplex scanner
(human)
POlHL-07293-17 0059 Non-invasive cardiovascular
measurements - Intracardiac blood flow measurement
(human)
ROlHL-07605-16 Congenital heart disease research
program (human, dogs)
R01HL09711-13 Instantaneous blood flow in ascending
aorta (human, dogs)
POlHL-10436-13 0001 A multidisciplinary study of
congenital heart disease - Assessment of the outlook for
children with congenital heart disease
P01HL10436-13 0008 A multidisciplinary study of
congenital heart disease - Physiologic consequences of
chronic hypoxemia (human)
POlHL-10436-13 0009 A multidisciplinary study of
congenital heart disease - Pathophysiology and
morphogenesis of congenital heart disease (human)
P01HL-n310-12 0080 Mechanisms of cardiovascular
disease - Metabolism of the hypertrophled myocardium
(human)
P01HL11310-12 0081 Mechanisms of cardiovascular
disease - Analysis of regional left ventricular function
(human)
POlHL-11310-12 9001 Mechanisms of cardiovascular
disease - Core support-hospital beds
POlHL-12373-10 0003 Cardiopulmonary physiology and
pathophysiology - Myocardial function in man
POlHL-12738-10 0080 Physiologic pharmacology and its
clinical applications - Electrophysiology of cardiac muscle
in the mitral valve (monkeys)
ROlHL-12777-09 Mechanisms in cardiac performance
(dogs, human)
POlHL-13330-08 0059 Mechanical circulatory support -
Physiologic evaluation of circulatory assistance (cattle)
R01HL14903-07 A new index of cardiac contractility
(human, dogs, baboons)
ROlHL-16461-05 Late results of valve replacement-
Computer analysis (human)
ROlHL-16938-05
human)
ROlHL-18850-03
Effect of physical forces on blood (dogs.
Classification code for Frank orthogonal
Diastolic properties of the left ventricle
ECG
ROlHL-19089-03
(human, dogs)
ROlHL-19136-03 Mucopolysaccharide metabolism in
cardiac anomalies (rats)
ROlHL-19203-03 Surgical approach to congenital heart
diseases (dogs, primates)
ROlHL-19451-03 0001 Functional characteristics of the
left heart - Ventricular performance using epicardial
radiopaque markers (human)
ROlHL-1945103 0003 Functional characteristics of the
left heart - Left ventricular segmental contraction (human,
dogs)
ROlHL-1981802 Endocarditis on prosthetic heart valves
(rabbits, human)
ROlHL-20533-09
rabbits)
ROlHL-20677-02
disease
R23HL-21973-01 Catecholamine metabolism and the heart
(human, guinea pigs)
ROlHL-22152-02 Ventricular dysfunction and cardiac
surgery (dogs)
HEART DISORDERS, VALVULAR, AORTIC VALVE
DISORDERS
POlHL-12373-10 0002 Cardiopulmonary physiology and
pathophysiology - Determinants of performance of the
whole heart (dogs)
** POlHL-14388-07 0162 Regulation of the circulation in
pathological states - Phasic coronary flow and myocardial
perfusion in aortic regurgitation (dogs)
P60HL-17269-04 0032 National heart and blood vessel
research and demonstration center - Clinical circulatory
assist device fabrication
(contd)
Pathogenesis of rheumatic fever (human.
Radionuclide studies In congenital heart
'Excludes routine methodotogy OR covers only general projects which preclude indexing at the specihc level.
"Oriented significantly to above subject.
M Grant has subpmjects describing specific research aspects.
See Appendix for investigator's name and grant number.
HEA
R01HL1796904 Function and stfucture ol semilunsi
vilvas (do|s)
•• ROIHL 18683 03 Lett ventiicle lunclion in aortic
ie(u(titation (tiuman)
HEART DISORDERS, VAIVUIAR, AORTIC VAIVE
STENOSIS
•• P01HL06285 18 0127 Catdiovasculat tespualory
physioloiY and biocliemistry Expenmental congenital
cardiac lesions In tetal lambs
PO1HL0628518 0178 Cacdiovasculai tespnatory
physiology and biocliemistry Biochemical regulation of
hypertrophy (rats, rabbits)
ROIHL 09474 U Natural history-congenital heart defects-
Joint study (human)
ROlHL-09476 10 Natural history, congenital heart detects
loint study
POIHL 10436 13 0001 A multidisciplinary study of
congenital heart disease Assessment of the outlook tor
children with congenital heart disease
POlHL-10436-13 0002 A multidisciplinary study of
congenital heart disease Myocardial performance,
metabolism and ultrastructure (human, cats, rats)
ROlHL-10718 10 Natural history ol congenital heart
detects -Joint study (human)
** ROIHL 12542-07 Natural history, congenital heart delects -
Joint study (human)
POIHL 1519407 0020 Pathophysiology of
cardiopulmonary dysfunction Coronary circulation in
arterjographically normal arteries (human)
P50HL 17655 04 0011 Study of ischemic heart disease
Core facility-Cardiovascular nuclear medicine (human, dog)
** ROlHL-17931-04 Normalized body surface potential maps
(children)
ROIHL 18338-04 Computer feedback study of cardiac
muscle mechanics (rats)
ROlHL-18794-04 Prospective studies of conduction disease
(human)
ROlHL-18848-03 Etiology and development of congenital
heart disease (dogs, cats)
ROlHL-19425-03 Cardiac function in hypertrophy (dog)
R01HL-20037-02 Lett ventricular-aortic bypass and
composite prosthesis (sheep, swine, cattle)
** ROlHL-20749-01 Developing heart -Biophysical aspects
(sheep)
HEART DISORDERS, VALVULAR, MITRAL
STENOSIS
ROlHL-05694-20 Functional pathology of cardiovascular
disease (human)
ROlHL-10009-13 Regional lung function in man
POlHL-10436-13 0001 A multidisciplinary study of
congenital heart disease - Assessment of the outlook for
children with congenital heart disease
ROlHL-11919-08 Pulmonary circulation in surgical heart
disease (human, dogs)
POlHL-15194-07 0020 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation in
arteriographically normal arteries (human)
P50HL-17670-04 0005 Study of ischemic heart disease -
Quantitative assessment of the vectorcardiogram (human)
ROlHL-18862-02 Thirst and its contribution to edema
(dogs)
ROIHL- 192 25-02 0004 Types and mechanims of
pulmonary hypertension - Structural changes in human
pulmonary circulation (human, animals)
** ROlHL-19391-03 Dynamic determinants of left ventricular
filling (dogs)
HEART DISORDERS, VALVULAR, PUIMONARY
VALVE STENOSIS
SEE ALSO CONGENITAL ABNORMALITIES, HEART DEFECTS,
TETRALOGY OF FALLOT
** POlHL-06285-18 0127 Cardiovascular-respiratory
physiology and biochemistry - Experimental congenital
cardiac lesions In fetal lambs
ROlHL-09474-11 Natural history-congenital heart defects-
Joint study (human)
ROlHL-09476-10 Natural history, congenital heart defects-
Joint study
ROlHL-10718-10 Natural history of congenital heart
defects-Joint study (human)
** ROlHL-12542-07 Natural history, congenital heart defects-
Joint study (human)
POlHL-12738-10 0076 Physiologic pharmacology and its
clinical applications - Pediatric cardiac eleclrophysiology
and pharmacology (human, dogs)
ROlHL-16329-04 Cardiac surgical effect on heart function
in infants (human)
ROlHL-18848-03 Etiology and development of congenital
heart disease (dogs, cats)
ROlHL-18862-02 Thirst and its contribution to edema
(dogs)
♦* ROlHL-20749-01 Developing heart-Biophysical aspects
(sheep)
HEART DISORDERS, VALVULAR INSUFFICIENCY
POlHL-04664-18 0001 Cardiovascular and lung dynamics
- X-ray projection image videodensitometry (dogs)
ROlHL-18156-02 Hemodynamics in curved arteries
R0U:L-18338-04 Computer feedback study of cardiac
muscle mechanics (rats)
257
•* ROIHL 2089503 0001 Cineangiographic studies of
cardiovascular system Videodensitometry and valvular
regurgitation (human, dogs)
HEART DISORDERS, VALVULAR INSUFFICIENCY,
AORTIC INSUFFICIENCY
POIHL 07293 1/ 0053 Non invasive cardiovascular
measurements Clinical evaluation of cardiac dimensions
using the duplex scanner (human)
POlHLO/293 17 0059 Non invasive cardiovascular
measurements Intracardiac blood How measurement
(human)
ROIHL 1655606 Left ventricular function in exercise
(dogs)
ROIHL 20678-02 Cardiovascular adaptation to stress in
disease states (dogs)
HEART DISORDERS, VALVULAR INSUFFICIENCY,
MITRAL INSUFFICIENCY
P01HL07293 17 0059 Noninvasive cardiovascular
measurements Intracardiac blood flow measurement
(human)
ROlHL-09711 13 Instantaneous blood flow in ascending
aorta (human, dogs)
POlHL-12738-10 0080 Physiologic pharmacology and its
clinical applications Electrophysiology of cardiac muscle
in the mitral valve (monkeys)
POlHL-12738-10 0136 Physiologic pharmacology and its
clinical applications -
ROlHL-12997-07 Myocardial defects induced by potassium
depletion (human, rats, cats)
POlHL-13330-08 0059 Mechanical circulatory support -
Physiologic evaluation of circulatory assistance (cattle)
** ROlHL-17909-04 Drug treatment of vascular scleroprotein
defects (human, turkeys)
ROlHL-18783-04 Detection and control of ventricular
premature beats (human)
** ROlHL-19391 03 Dynamic determinants of left ventricular
filling (dogs)
HEART DISORDERS, VALVULAR INSUFFICIENCY,
TRICUSPID INSUFFICIENCY
POlHL-12738-10 0075 Physiologic pharmacology and its
clinical applications - Pediatric cardiac electrophysiology
and pharmacology (human, dogs)
P50HL-141 87-07 0005 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses - Pulmonary
hypertension and cardiac function (dogs, human)
HEART DISORDERS CHEMOTHERAPY
SEE ALSO CARDIOVASCULAR AGENTS, ANTIARRHYTHMIC
AGENTS
SEE ALSO CARDIOVASCULAR AGENTS, ARRHYTHMIC AGENTS
SEE ALSO CARDIOVASCULAR AGENTS, CARDIOTONIC AND
CARDIOPROTECTIVE DRUGS (GENERAL)
ROlHL-04666-19 Artificially paced hearts -Technology,
physiology (human, dogs)
ROlHL-05806-18 Analysis of antiarrhythmic agents (dogs,
rabbits)
** R01HL05875-18 Pathologic metabolic and physiologic
studies of heart (human, dogs, cats)
** POlHL-06285-18 0155 Cardiovascular-respiratory
physiology and biochemistry - Therapeutic alterations,
contractile state in heart failure
M POlHL-06308-18 Mechanisms and therapy of circulatory
disease
*♦ POlHL-06308-18 0011 Mechanisms and therapy of
circulatory disease - Blood flow and electrical dysfunction
in ventricular arrhythmia (human)
** POlHL-06308-18 0029 Mechanisms and therapy of
circulatory disease ■ Characterization of the patient with
recurrent ventricular arrhythmias
** POlHL-06308-18 0037 Mechanisms and therapy of
circulatory disease - Electrophysiology, blood flow, and ANS
in ventricular fibrillation (dogs)
POlHL-06308-18 0038 Mechanisms and therapy of
circulatory disease - Electrophysiology of ventricuair
arrhythmias associated with ischemia (dogs)
POlHL-06312-17 0016 Surgical cardiology ■ Effect of
hydralazine on infarct size following coronary occlusion
(human)
POlHL-063 12-17 0030 Surgical cardiology - Total
artificial heart (calves)
POlHL-063 12-17 0051 Surgical cardiology - Diuretic
therapy on myocardial electrolyte composition and water
content (human)
** POlHL-06370-17 0014 Cardiopulmonary and renal
pathology research center - Quantitative morphology in
cardiac disease (human, rats, dogs)
** POlHL-06664-17 0034 Cardiopulmonary function in
remediable vascular disease - Role of hyperosmolar agents
in ischemic heart disease (dogs)
ROlHL-07139-17 Cardiodynamics and metabolism of
congestive failure (human, dogs)
** ROlHL-07776 15 Sudden death and cardiac arrhythmias
(human, dogs, cats)
ROlHL-08570-15 Pharmacologic and reflex influence on
vascular tone (dogs, rabbits)
•* ROlHL-08888-12 Cooperative study of drugs and coronary
heart disease (men)
ROlHL-08892-10 Cooperative study of drugs and coronary
heart disease
M
HEA
ROIHI 09914 13 The myocardium in diibttet (inllitui
(dogs, monkeys)
ROIHL 10445 09 Cooperative study ol drugs and coroniiy
heart disease (men)
ROIHL 10705 09 Cooperative study ol drugs and coronary
heart disease (men)
ROIHL 11372 08 Cooperative study of drugs and coronary
heart disease (men)
ROIHL 12322 10 Extrinsic factors influencing myocardial
perlormance (dogs, swine)
ROIHL 12/77 09 Mechanisms in cardiac performance
(dogs, human)
POIHL 13108 09 0019 Clinical heart transplantation
Elfecl of autonomic nervous system on arrhythmias
(human)
ROIHL 1363907 Factors altering the course of myocardial
dyslunction (cats)
ROIHL 14646-05 Pathophysiology of myocardial ischemia
(dogs, rats)
ROIHL 14717-06 Hemodynamics and heart structure
Ventricular overload (dogs)
ROlHL-15190 07 Physiological basis of arrhythmias and
their therapy (human)
ROIHL 16076-06 Electrophysiology of fibrillation and
defibrillation (human)
R01HL1624606 Immunologic studies in
postpericardiotomy syndrome (human)
P50HL 17646-04 0001 Study of ischemic heart disease -
Core clinical investigation unit
■ P50HL 17646 04 0015 Study of ischemic heart disease -
Protecting ischemic myocardium in patients with evolving
myocardial infarction
P50HL- 17648-04 Study of ischemic heart disease
P50HL-17651-04 0015 Ischemic heart disease specialized
center of research Peripheral circulation in acute
myocardial ischemia and infarction (human)
■ P50HL-17651-04 0016 Ischemic heart disease specialized
center of research Retroperfusion of coronary venus
circulation with therapeutic agents (dogs)
P50HL-17651-04 0022 Ischemic heart disease specialized
center of research - Electrophysiology-Mechanism and
pharmacology of arrhythmias (human, dog)
P50HL-17651-04 0043 Ischemic heart disease specialized
center of research Gradual reperfusion following acute
coronary occlusion (dog)
P50HL- 17655-04 Study of ischemic heart disease
* P50HL-17655-04 0001 Study of ischemic heart disease -
Intravenous nitroglycerin-Ventricular function and infarct
size (human, dog)
* P50HL- 17655-04 0009 Study of ischemic heart disease •
Random trial of medical and surgical therapy in unstable
angina (human)
P50HL-17655-04 0014 Study of ischemic heart disease -
Blood flow and gas tension in myocardial ischemia and
infarction (dog. monkey)
* P50HL-17665-04 0002 Study of ischemic heart disease -
Reducing acute anterior myocardial infarction-Beta
adrenergic blockade (human)
* P50HL-1766504 0013 Study of ischemic heart disease -
National cooperative study in unstable angina pectoris
(human)
P50HL-17665-04 0020 Study of ischemic heart disease -
Ischemic injury to myocardium during measured states of
ischemia (human)
P50HL-17665-04 0026 Study of ischemic heart disease -
Anesthesia-Myocardial ischemia and hemodynamics in
coronary disease (human)
P50HL- 17667-04 0001 Study of Ischemic heart disease -
Natural history of ischemic heart disease (human)
P50HL-17667-04 0018 Study of ischemic heart disease ■
Arrhythmias in ischemic heart disease (human)
P50HL-17667-04 0019 Study of ischemic heart disease -
Assessment of long-term results of coronary artery bypass
grafting (human)
P50HL-17667-04 0038 Study of ischemic heart disease -
Clinical core unit
** P50HL-17669-04 0012 Ischemic heart disease center
(SCOR) - Circulatory assistance (human, dog)
P50HL-17669-04 0023 Ischemic heart disease center
(SCOR) - Patients with acute myocardial infarction and
myocardial ischemia (human)
P50HL-17670-04 0020 Study of ischemic heart disease ■
Radionuclide evaluation of coronary artery disease (human,
dog)
** P50HL-17682-04 0001 Study of ischemic heart disease -
Studies in acute and chronic ischemic heart disease
(human)
P50HL-17682-04 0008 Study of ischemic heart disease -
Clinical core unit
ROlHL-17759-03
(dogs, human)
ROlHL-18204-03
(turkeys)
ROlHL-18288-04
Studies of myocardial reactive hyperemia
Regional blood flow in viral myocarditis
Intraoperative protection of the
myocardium (dogs, rats)
ROlHL-18537-04 Regional blood flow after acute
myocardial injury (dogs)
ROlHL-18769-04 Studies in survivors of lethal arrhythmias
(human)
ROlHL-18783-04 Detection and control of ventricular
premature beats (human)
(contd)
'Excludes routine methodology OR covers only general projects which preclude
"Oriented significantly to above subject
indexing attlie specific level.
M Grant has subproiects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
HEA
258
HEA
ROlHL-18794-04 Prospective studies of conduction disease
(human)
ROlHI.18805-04 0004 Sudden cardiac death and the
onset of myocardial infarction • Sudden death survivors-
Clinical follow-up and therapy (human)
ROlHL-18824-03 Mechanisms of heart failure In
myopathic hamster
ROlHL-18984-01 P50 effect on exercise limit In stable
angina (human)
ROlHL-19044-03 Effect of drugs on development of
cardiac failure (cats)
ROlHL-19072'03 Modification of tissue injury in
myocardial Infarction (dogs, human)
R01HL1918203 Surgical aspects of myocardial
hypertrophy (dogs)
POlHL-19259-03 0004 Digoxinspecific antibody in human
therapy - Digitalis-specific antibodies pharmacological
studies (human, dogs, sheep)
ROlHL-19451-03 0004 Functional characteristics of the
left heart - Quantitative coronary arteriography (human)
Vasodilators In experimental myocardial
Surgically Induced myocardial edema
Drug-induced alterations in infarct size
Prospective bundle branch block study
ROlHL-19937-02
infarction (dogs)
ROlHL-20080-02
(dogs)
ROlHL-20199-02
In the rat
ROlHL-20238-02
(human)
ROlHL-20394-03 Complement activation by heart
subcellular membranes (human, dog)
POlHL-20552-02 The development and regression of
cardiac hypertrophy
POlHL-20552-02 0002 The development and regression of
cardiac hypertrophy - Effect of treatment on the
hypertrophied left ventricle (rats)
POlHL-20552-02 0003 The development and regression of
cardiac hypertrophy - Muscle mechanics of the
hypertrophied left ventricle (rats)
ROlHL-20558-02 Cardiac electrophyslology-Effects of ions
and drugs
ROlHL-20572-02 0003 Hemodynamic relations to
metabolism in hypertension - Cardiac output and organ
blood flow In hypertension (rats)
ROlHL-21052-01 Evaluation of a digitalis therapy advisor
R23HL-21 151-02 Ischemic myocardium-Delivery of blood
flow and drugs (dogs)
R23HL'21434'02 Intrinsic control of coronary blood flow by
chemicals (guinea pigs)
ROlHL-21684-02 Radionuclide Infarct sizing and therapy
evaluation
ROlHL-21684-02 0001 Radionuclide Infarct sizing and
therapy evaluation - Evaluating preservation of ischemic
myocardium by radioisotope methods (dog)
ROlHL-2 1684-02 0002 Radionuclide Infarct sizing and
therapy evaluation - Evaluating myocardial Imaging agents
in global and regional Ischemia (rabbits)
ROlHL-2 1684-02 0004 Radionuclide infarct sizing and
therapy evaluation - Image analysis -Kinetics of infarction,
ventricular function (human, animal)
ROlHL-21684-02 0005 Radionuclide infarct sizing and
therapy evaluation - Clinical evaluation of radioisotope
imaging methods for quantifying Infarct size
ROlHL-22258-01 New aspects of pharmacology related to
carbonic anhydrase
ROlHL-22470-01 Liposome myocardial uptake In infarct
and ischemia (dogs, rats, mice)
ROlHL-22522-01
antagonists
R01HL-22750-01
rhythm (human)
ROlHL-22977-01
heart failure (human, dogs)
ROlHL-23071-01
(dog, human)
ROlHL-23653-01
(dogs)
ROlHL-23970-01
Cardioselectlvlty of beta-adrenoceptor
DIgoxIn In heart failure with sinus
Role of vasoconstrictor mechanisms in
an, dogs)
Electrophyslology of lethal arrhythmias
Protection of the Ischemic myocardium
Mechanisms and control of sudden
cardiac death (human, dog)
Effects of digoxin therapy In newborn
Aspirln-myocardial Infarction study
Center for aspirln-myocardial infarction
Therapy to protect Ischemic myocardium -
Coordinating center for propranolol heart
ECG center for proprancolo heart trial
Central laboratory for propranolol heart
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
ROlHL-23980-01
and adult sheep
NOlHV-52901-06
NOlHV-52941-04
study (human)
NOlHV-62960-00 Techniques to protect ischemic
myocardium and minimize Infant size (human)
NOlHV-72940-02 Therapy to protect Ischemic myocardium
(human)
NOlHV-72941-02
Clinical tests
NOlHV-72948-03
trial (human)
NOlHV-72949-03
NOlHV-72950-02
trial
NOlHV-72951-03
(human)
NOlHV-72952-02
(huamn)
N01HV-72954-06
(human)
N01HV-72955-02
(human)
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trail
Clinical center for propranolol heart trial
Clinical center propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
** NOlHV-72956-02
(human)
*♦ NOlHV-72957-02
(human)
** NOlHV-72958-02
(human)
** NOlHV-72959-04
(human)
** NOlHV-72960-02
(human)
** NOlHV-72963-02
(human)
** NOlHV-72964-02
(human)
" NOlHV-72965-02
** N01HV-7296G-03
** NOlHV-72967-02
(human)
** NOlHV-72968-03
** NOlHV-72969-02
(human)
** NOlHV-72970-04
(human)
** NOlHV-82900-03
(human)
*• NOlHV-82901-02
(human)
** NOlHV-82902-02
(human)
** NOlHV-82903 02
(human)
** NOlHV-82904-02
(human)
** NOlHV-82905-02
(human)
** NOlHV-82906-02
(human)
** NOlHV-82907-02
(human)
** NOlHV-82908-02
(human)
** NOlHV-82909-02
(human)
** NOlHV-82910-00
(human)
HEART DISORDERS CONGENITAL
SEE CONGENITAL ABNORMALITIES, HEART DEFECTS
HEART DISORDERS DIAGNOSIS (INCL EXAMS)*
SEE ALSO HEART VISUALIZATION*
SEE ALSO HEART VISUALIZATION, CINEANGI0CARDI06RAPHY*
SEE ALSO HEART VISUALIZATION, EPICARDIAL MAPPING
SEE ALSO HEART VISUALIZATION, HEART SCANNING*
ROlHL-03180-21 Relation of lymphatics to
cardiopulmonary function (dogs)
M POlHL-04664-18 Cardiovascular and lung dynamics
*♦ POlHL-04664-18 0001 Cardiovascular and lung dynamics
- X-ray projection image videodensitometry (dogs)
** POlHL-04664-18 0002 Cardiovascular and lung dynamics
- X-ray cross section Imaging of organs (dogs)
** POlHL-04664-18 0003 Cardiovascular and lung dynamics
- X-ray projection image videometry (human, dogs)
** POlHL-04664-18 0010 Cardiovascular and lung dynamics
- Left ventricular dynamics (human)
** POlHL-04664-18 0011 Cardiovascular and lung dynamics
- Detection of abnormal segments of the human ventricle
by measure of asynergy
POlHL-04664-18 0012 Cardiovascular and lung dynamics
- Quantitative single plane left ventricular angiography
(human)
POlHL-04664-18 0013 Cardiovascular and lung dynamics
- Ventricular function In coronary disease using NTG and
ventriculograms (human)
POlHL-04664-18 0014 Cardiovascular and lung dynamics
- Clinical application of computer analysis of ventricular
wall motion
** POlHL-04664-18 0015 Cardiovascular and lung dynamics
- Computer system for the cardiovascular laboratory
** ROlHL-04666-19 Artificially paced hearts -Technology,
physiology (human, dogs)
ROlHL-05694-20 Functional pathology of cardiovascular
disease (human)
** POlHL-06285-18 0164 Cardiovascular-respiratory
physiology and biochemistry - CPK MB isoenzyme
concentration to quantify infarct size (human, animals)
M POlHL-06308-18 Mechanisms and therapy of circulatory
disease
P01HI.-06308-18 0010 Mechanisms and therapy of
circulatory disease - Ventricular arrhythmias during exercise
to CHD and myocardial Ischemia (human)
POlHL-06308-18 0011 Mechanisms and therapy of
circulatory disease - Blood flow and electrical dysfunction
in ventricular arrhythmia (human)
** POlHL-06308-18 0012 Mechanisms and therapy of
circulatory disease - Echocardiographic evaluation of
hemodynamics of arrhythmia (human)
** POlHL-06308-18 0042 Mechanisms and therapy of
circulatory disease - Echocardiographic assessment of
arrhythmias -Myocardial tissue type (human, dogs)
** POlHL-06308 18 0043 Mechanisms and therapy of
circulatory disease - Exercise and echocardiographic
examining techniques (human)
*Excludes routine methodology OR covers only general projects which preclude indexing
**Orieflted significantly to above subject.
POlHL-06308-18 0044 Mechanisms and therapy of
circulatory disease - Echocardiography to determine site of
ectopic impulse formation (human, dogs)
POlHL-06312-17 0013 Surgical cardiology - Aortocoronaty
vein bypass grafting (human)
POlHL-06312-17 0016 Surgical cardiology - Effect of
hydralazine on infarct size following coronary occlusion
(human)
POlHL-06314-17 0065 Immunologic mechanisms in
cardiovascular disease - Transplantation biology and
clinical transplantation
ROlHL-0713917 Cardiodynamics and metabolism of
congestive failure (human, dogs)
POlHL-07293-17 Non-Invasive cardiovascular
measurements
POlHL-07293-17 0041 Non-invasive cardiovascular
measurements - Ventricular volumes and dimensions
(human)
POlHL-07293-17 0042 Non-invasive cardiovascular
measurements - Ventricular imaging software (human)
POlHL-07293-17 0043 Non-Invasive cardiovascular
measurements - ECHO-Doppler instrumentation for cardiac
measurements (human)
POlHL-07293-17 0044 Non-invasive cardiovascular
measurements - Cardiac duplex scanner
POIHL-07293-17 0045 Non-invasive cardiovascular
measurements - Cardiac scanner transducer position
locating systems (human)
POlHL-07293-17 0046 Non-Invasive cardiovascular
measurements - Cardiac scanner signal processors
POlHL-07293-17 0047 Non-invasive cardiovascular
measurements - Cardiac scanner system software
POlHL-07293-17 0048 Non-invasive cardiovascular
measurements - Cardiac scanner recording and display
systems component
POlHL-07293-17 0051 Non-invasive cardiovascular
measurements - Physiologic evaluation of duplex scanner
(dogs)
POlHL-07293-17 0052 Non-Invasive cardiovascular
measurements - Clinical evaluation of the duplex scanner
(human)
POlHL-07293-17 0053 Non-invasive cardiovascular
measurements - Clinical evaluation of cardiac dimensions
using the duplex scanner (human)
POlHL-07293-17 0059 Non-invasive cardiovascular
measurements - Intracardiac blood flow measurement
(human)
ROlHL-07605-16 Congenital heart disease research
program (human, dogs)
ROlHL-07776-15 Sudden death and cardiac arrhythmias
(human, dogs, cats)
ROlHL-09315-15 Coronary insufficiency and myocardial
revascularization (human, dogs)
R01HL-09831-12 Effect of resistivity variations on
electrocardiogram (human)
ROlHL-09914-13 The myocardium in diabetes mellitus
(dogs, monkeys)
POlHL-10342-13 0008 The integrated function of
respiration and circulation - Respiratoiv mechanics and the
circulation (human, dogs)
ROlHL-10417-12 Multiple systems in electrocardiography
(human)
' P01HL-10436-13 0016 A multldisciplinary study of
congenital heart disease - Genetic studies of congenital
heart disease (human)
POlHL-1 1310-12 Mechanisms of cardiovascular disease
POlHL-1 1310-12 0055 Mechanisms of cardiovascular
disease - Ventricular pressure-volume after Intracardiac
surgery (human)
POlHL-11310-12 0056 Mechanisms of cardiovascular
disease - Cardiac output response to blood pressure
reduction in infants (human)
P01HL11310-12 0071 Mechanisms of cardiovascular
disease - Electrophysiological studies of atrial flutter
(human)
POlHL-11310-12 0072 Mechanisms of cardiovascular
disease - Electrophysiological studies of atrial tachycardia
with block (human)
POlHL-11310-12 0073 Mechanisms of cardiovascular
disease - Electrophysiological study of atrial fibrillation
(human)
' POlHL-11310-12 0091 Mechanisms of cardiovascular
disease - Noninvasive techniques in cardiovascular
diagnosis (human)
' POlHL-11310-12 9001 Mechanisms of cardiovascular
disease - Core support-hospital beds
' POlHL-1 1310-12 9002 Mechanisms of cardiovascular
disease - Core support-centralized electronic laboratory
P01HL12373-10 Cardiopulmonary physiology and
pathophysiology
POlHL-12373-10 0002 Cardiopulmonary physiology and
pathophysiology - Determinants of performance of the
whole heart (dogs)
POlHL-12373-10 0003 Cardlopulmonai> physiology and
pathophysiology - Myocardial function In man
POlHL-12373-10 0005 Cardiopulmonary physiology and
pathophysiology - Characterization of fetal and neonatal
myocardium (human, cats)
' ROlHL-12611-10 Basic and clinical studies of the ST-T
deflection (human, dogs)
ROlHL-12711-09 Mathematical approach to cardiovascular
mechanics (human, animals)
(contd)
at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix (or investigator's name and grant number.
HEA
POIHL 1273810 0035 Physiolojlc phBfiincology and its
clinicsl »pplic«lions Function and dyslunction ol the
sinoatfial node (human)
POIHI 12/38 10 011/ Physiologic phatmacology and its
clinical applications Ventricular anhythmias in ischemic
heart disease (human)
POIHL 1273810 0127 Physiologic phaimacology and its
clinical applications Cardiac electrical activity (human.
animals)
•* ROIHL 13036 08 Coronary thiombosisEtfects on
myocardium and in vivo detection (dogs, monkeys)
M POIHI 13108 09 Clinical heart transplantation
** POIHL 1310809 0001 Clinical heart transplantation •
Therapy and prognosis (human)
♦• P01HL13108 09 0002 Clinical heart transplantation
Preoperative immunologic studies of cardiac recipients
•• POIHL 13108 09 0003 Clinical heart transplantation
Endomyocardial biopsy pathology
•* POIHL 13108-09 0009 Clinical heart transplantation ■ B
cell alloantigens in cardiac allograft compatibility (human)
•• POIHL 13108 09 0010 Clinical heart transplantation
Serum factors inhibiting lymphocyte responses in MLC
(human, bush babies)
** POIHL 1310809 0012 Clinical heart transplantation •
Human T cell sheep erythrocyte receptors
•• POIHL 13108-09 0014 Clinical heart transplantation
Platelets and coagulation in accelerated graft coronary
atherosclerosis
M P01HL1373707 Assisted circulation
** POlHL-1373707 0007 Assisted circulation -
Determination of cardiac status by use of balloon pump
(dogs)
** POIHL 13737-07 0038 Assisted circulation
Distinguishing the ischemic ventricle from scarred ventricle
by balloon pumping
** POlHL-1385116 Cyclotron produced isotopes in biology
and medicine (human, animals)
POlHL-14388-07 0217 Regulation of the circulation in
pathological slates ■ Fluid mechanics of aortic flow (dogs,
human)
ROlHL-1457105 Myocardial preservation and coronary
repertusion (baboons, dogs)
ROlHL-14651-05 Mechanical behavior of left ventricle
(dogs, rats)
R01H11478507 Ultrasonic scattering for tissue
characterization (dogs, cattle, human)
** ROlHL-15016-07 Nev» concepts in cardiac ultrasound
technology (human)
** POlHL-1 5194-07 0017 Pathophysiology of
cardiopulmonary dysfunction ■ Coronary circulation and
effects of arteriographic lesions on flow (human)
** P01HL15194-07 0025 Pathophysiology of
cardiopulmonary dysfunction • Myoglobinemia as an index
of myocardial ischemia and infarction
** ROlHL-15983-04 Regional myocardial blood flow (dogs)
** R01HL16076-06 Electrophysiology of fibrillation and
defibrillation (human)
R01HL16260-04 Development of clinical cine ultrasound
cardiography
ROlHL-16292-05 0009 Surgery and non-obstructive
coronary insufficiency - Exercise and supply-demand
balance (human)
ROlHL-16292-05 0020 Surgery and non-obstructive
coronary insufficiency - Limitation of transthoracic ECG in
detecting subendocardial ischemia (dogs)
ROlHL-16412-04 Release of nucleosides from the ischemic
heart (human, dogs)
R01HL-1G908-04 Myocardial function, risk factors and
future CHO (men)
ROlHL-15909-04 Myocardial function, risk factors and
future CHD (men)
** P60HL-17269-04 0007 National heart and blood vessel
research and demonstration center - Correlative studies of
experimental myocardial ischemia (dog)
" P60HL-1 7269-04 0027 National heart and blood vessel
research and demonstration center - Non-invasive
evaluation of cardiac function-lschemic heart disease
(human, dog)
ROlHL-17532-04 Infarct size-ECG, angio. path, correlation
in dogs
" P50HL-1 7646-04 0001 Study of ischemic heart disease -
Core clinical investigation unit
** P50HL-1 7646-04 0002 Study of ischemic heart disease -
Core data management
" P50HL-1764604 0010 Study of ischemic heart disease -
Compliance in ischemic myocardium -Altered cardiac
performance (human, dogs)
M P50HL-1 7648-04 Study of ischemic heart disease
** P50HL-17648-04 0004 Study of ischemic heart disease -
Radionuclide imaging studies (human, pig)
M P50HL-17651-04 Ischemic heart disease specialized center
of research
** P50HL-17651-04 0023 Ischemic heart disease specialized
center of research - Development of multipurpose catheter
for monitoring and electronic pacing
** P50HL-17651-04 0039 Ischemic heart disease specialized
center of research Measurement and prediction of infarct
size (human, dog)
** P50HL1 7651-04 0048 Ischemic heart disease specialized
center of research - Non-invasive detection of ischemic
heart disease
M P50HL-1 7655-04 Study of ischemic heart disease
259
* PSOHL'l 7655-04 0011 Study of ischemic heart disease
Core facility Cardiovascular nuclear medicine (human, dog)
* P50HL 1/665 04 0008 Study ol ischemic heart disease
Core laboratory CPK isoenzyme measurement and
myocardial necrosis evaluation
* P50HL 1/665 04 0028 Study ol ischemic heart disease
Pathologic and biochemical studies of ischemic
myocardium (human, dog)
P50HL 17665 04 0030 Study of Ischemic heart disease
Data management
II P50HL 1/66/04 Study of ischemic heart disease
* P50HL 1766/ 04 0030 Study ol ischemic heart disease
Computerized clinical data acquisition and processing
P50HL 1/66/04 0042 Study of ischemic heart disease
Core Central instrumentation and software
* P50HL 1/669 04 Ischemic heart disease center (SCOR)
'* P50HL 17669 04 0023 Ischemic heart disease center
(SCOR) Patients with acute myocardial infarction and
myocardial ischemia (human)
VI P50HL 17670-04 Study of ischemic heart disease
P50HL 17670-04 0001 Study of ischemic heart disease ■
Data management
•* P50HL 17670-04 001/ Study of ischemic heart disease
Core enzymology laboratory (human)
M P50HL 17682-04 Study of ischemic heart disease
P50HL-17682-04 0003 Study of ischemic heart disease -
Effects of myocardial revascularization in man
** P50HL- 17682 04 0005 Study of ischemic heart disease
Regional myocardial perfusion deficits and segmental
contraction disorders in man
** P50HL- 17682-04 0008 Study of ischemic heart disease •
Clinical core unit
** P50HL-1768204 0010 Study of ischemic heart disease -
Core clinical enzyme laboratory (human, mice, dogs, rats)
** P50HL-17682-04 0011 Study of ischemic heart disease •
Nuclear medicine core unit (human, dogs, rabbits, mice)
** ROlHL-17931-04 Normalized body surface potential maps
(children)
M ROlHL-17993-04 Ventricular dynamics from surgically
inserted markers
ROlHL-1799304 0002 Ventricular dynamics from
surgically inserted markers - Left ventricle function in
human cardiac allograft
** ROlHL-18454-03 Maximal exercise testing in
hyperlipidemic children
** ROlHL-18567-03 A routine diagnostic test for minimal
heart damage (human, rat)
** POlHL-18708-03 0010 Oxygen, energy and contractility in
cardiac tissue - Tissue oxygen utilization (rats, dogs)
ROlHL-18744-03 Preparation of radiopharmaceuticals from
drug analogs
** ROIHL-18769-04 Studies in survivors of lethal arrhythmias
(human)
** R01HL-18783-04 Detection and control of ventricular
premature beats (human)
** ROlHL-18794-04 Prospective studies of conduction disease
(human)
ROIHL 18800-04 Prospective study of resuscitated sudden
death victims (human)
M ROlHL-18805-04 Sudden cardiac death and the onset of
myocardial infarction
** ROlHL-18805-04 0003 Sudden cardiac death and the
onset of myocardial infarction - Prediction from clinical and
laboratory assessments (human)
** ROlHL-18805-04 0005 Sudden cardiac death and the
onset of myocardial infarction - Sudden death survivors-
Radionuclide studies (human)
M ROlHL-18808-04 Prediction and prevention of sudden
cardiac death
ROlHL-18968-03 Computer technology for transaxial
tomography
** ROlHL-191 27-03 Synthesis of molecules for myocardial
imaging (rats)
** ROlHL-19135-04 Heterogeneity of regional myocardial
blood flow (dogs)
ROlHL-19246-03 Regression of cardiac hypertrophy-
Myocardial and renal (human)
M POlHL-19259-03 Digoxin-specific antibody in human
therapy
POlHL-192 59-03 0001 Digoxin-specific antibody in human
therapy - Primary structure of monoclonal antibodies
(rabbits)
POlHL-19259-03 0003 Digoxin-specific antibody in human
therapy - Synthesis of dogoxin-specific antibody in
continuous cell culture (human, sheep)
** ROlHL-19370-03 Coronary capillary exchange-The effects
of ischemia (dogs, sheep)
M ROlHL-19451-03 Functional characteristics of the left
heart
** ROlHL-19451-03 0001 Functional characteristics of the
left heart - Ventricular performance using epicardial
radiopaque markers (human)
ROlHL-19451-03 0003 Functional characteristics of the
left heart - Left ventricular segmental contraction (human,
dogs)
** ROlHL-19451-03 0004 Functional characteristics of the
left heart - Quantitative coronary arteriography (human)
** ROlHL-19768-02 Recording and analysis of low levels
cardiac signals (human, dogs)
ROlHL-1996103 Management of hemosiderosis in
thalassemia (children, adults)
HEA
ROIHI 20000 03 Iron overload in homozygous bell
thalassemia (human)
• ROIHI 2023802 Prospective bundle branch block study
(human)
* ROIHL 20283 02 Maintenance of cellular integrity in
ischemic hearts (cats)
ROIHL 203/4 03 Myocardial function Risk factors and
future CHD (human)
ROIHL 2059/ 02 Electrophysiologic correlates ol
myocardial ischemia (human, dogs, rabbits)
• ROIHL 20645 01 Etiology of myocardial inlaction (human)
* ROIHL 20/4901 Developing heart Biophysical aspects
(sheep)
ROlHL-20895-03 0001 CIneangiographic studies of
cardiovascular system Videodensitometry and valvular
regurgitation (human, dogs)
ROIHL 20895 03 0002 Cineangiographic studies of
cardiovascular system Coronary disease -Regional
myocardial blood flow (human, dog)
•* ROIHL 2089503 0005 Cineangiographic studies of
cardiovascular system Computerized axial tomography
Cardiac wall motion and infarction (dogs)
*• R23HL 2119/02 Right ventricular contraction and
relaxation (dogs)
** ROIHL 212/8-01 Abnormal cardiac wall motion viewed
ultrasonically (human, dogs, phantoms)
ROIHL 21283-02 Simulation studies of the ECG in acute
ischemia (and human)
R23HL-21292-01 Human ventricular activation- Patterns
and mechanisms (human)
** R23HL-21347 02 Accessory pathways and supraventricular
tachycardia
ROlHL-21425-02 Servo-simulated compliance changes-A
reversible Ml (dogs)
ROIHL 21654-01 Autonomic determinants of arrhythmia
due to ischemia (cats)
** ROlHL-21706-02 Nuclear magnetic resonance and
myocardial ischemia (rats)
** ROlHL-21820-01 Regulatory role of myosin in cardiac
hypertrophy (dogs)
** ROIHL 21846-01 Cardiac failure detection by radiography
and optics (monkeys)
** ROlHL-21985-01 Videoroentgenography in congenital heart
disease
** R23HL-22004-01 Imaging and ECG studies in acute and
chronic IHD (human)
** ROlHL-22080-01 Phosphorus NMR studies on cardiac
tissue (rats, rabbits)
ROlHL-22321-01 Cardiac output from the
pneumocardiogram (dogs)
ROlHL-22326-01 Noninvasive measurement of cardiac
output (dogs)
ROlHL-223/8-01 Psyco-somatic predictors of CHD in
adolescence (human)
** ROlHL-22750-01 Digoxin in heart failure with sinus
rhythm (human)
ROlHL-22801-01 Analysis of coronary artery behavior
(dogs)
ROlHL-22809-01 Coronary-prone behavior and
cardiovascular reactivity (human)
•• ROlHL-22952-01 Validation of quantitative coronary
arteriography (dogs)
ROlHL-22982-01 Multicenter postcoronary risk
stratification program (human)
NOlHV-42933-09 Multiple risk factors in coronary heart
disease (human)
NOlHV-62960-00 Techniques to protect ischemic
myocardium and minimize infant size (human)
HEART DISORDERS DIAGNOSIS,
BALUSTOCARDIOGRAPHY*
** ROlHL-16908-04 Myocardial function, risk factors and
future CHD (men)
** ROlHL-16909-04 Myocardial function, risk factors and
future CHD (men)
** ROlHL-20374-03 Myocardial function-Risk factors and
future CHO (human)
HEART DISORDERS DIAGNOSIS,
ELECTROCARDIOGRAPHY*
SEE ALSO CARDIOVASCULAR DISORDERS DIAGNOSIS,
EXERCISE STRESS TESTING*
SEE ALSO HEART DISORDERS DIAGNOSIS.
VECTORCARDIOGRAPHY*
** ROlHL-01486-23 Quantitative study of T-wave mechanisms
(human, rabbits, dogs, chickens)
POlHL-04664-18 0015 Cardiovascular and lung dynamics
- Computer system for the cardiovascular laboratory
** POlHL-06308-18 0010 Mechanisms and therapy of
circulatory disease - Ventricular arrhythmias during exercise
to CHD and myocardial ischemia (human)
ROlHL-08892-10 Cooperative study of drugs and coronary
heart disease
** ROIHL 09831-12 Effect of resistivity variations on
electrocardiogram (human)
** ROlHL-10417-12 Multiple systems in electrocardiography
(human)
POlHL-10539-12 0064 Pathophysiology of circulation -
Exercise physiology and pathophysiology (human)
M POlHL-11307-12 Biophysical studies in pediatric
cardiology
(contd)
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
**0riented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
■:^cVuwikiuuwwtAA
HEA
** POlHL-11307-12 0002 Biophysical studies in pediatric
cardiology - Cardiac extracellular electrophysiology (human,
dog, chimpanzee)
P01HL-n307-12 9001 Biophysical studies in pediatric
cardiology - Core support-computer science
** POlHL-1130712 9002 Biophysical studies in pediatric
cardiology - Biomedical engineering
** P01HL11310-12 0075 Mechanisms of cardiovascular
disease - Bipolar atrial electrograms from Bachmann's
bundle (dogs)
** POlHL-1131012 0092 Mechanisms of cardiovascular
disease - Exercise electrophysiology (human)
** POlHL-11310-12 0093 Mechanisms of cardiovascular
disease - Multiple dipole electrocardiogram project (human,
dogs)
POlHL-11310-12 9002 Mechanisms of cardiovascular
disease - Core support-centralized electronic laboratory
** ROlHL-12611-10 Basic and clinical studies of the ST-T
deflection (human, dogs)
POIHL 1273810 0076 Physiologic pharmacology and its
clinical applications - Pediatric cardiac electrophysiology
and pharmacology (human, dogs)
POlHL-12738-10 0107 Physiologic pharmacology and its
clinical applications Blood superfused cardiac fibers
(dogs)
POlHL-12738-10 0124 Physiologic pharmacology and its
clinical applications - Counterpulsation on myocardial
ischemia measured by carbon dioxide tension (dogs)
** POlHL-12738-10 0128 Physiologic pharmacology and its
clinical applications - Recording electrograms from
specialized cardiac tissues (human, dogs)
M POlHL-13480-09 Cardiac electrophysiology
** P01HL13480-09 0017 Cardiac electrophysiology - Body
surface potential mapping (human, dogs)
P01HL13480-09 0026 Cardiac electrophysiology - Neural
influences on cardiac electrophysiology and contraction
(dog, cat)
** P01HL13480-09 0028 Cardiac electrophysiology ■ Stress
electrocardiography (human, dogs)
** POlHL-13480-09 0032 Cardiac electrophysiology - Cardiac
activation sequence (dogs)
POlHL-13737-07 0013 Assisted circulation ■ Incorporation
of sensors (human, dogs)
P50HL-14214-07 0030 Newborn lung center for hyaline
membrane disease - Effects of ductal patency-Impedance
cardiography and echocardiography (human)
** ROlHL-14688-05 Myocardial assessment by inverse
electrocardiography (monkey)
** ROlHL-15047-06 Digital computer analysis of the
electrocardiogram (human)
** P01HL-15265-D5 0011 Program on surgical control of the
hyperlipidemias - Central electrocardiography laboratory
(human)
** ROlHL-16292-05 0020 Surgery and non-obstructive
coronary insufficiency - Limitation of transthoracic ECG in
detecting subendocardial ischemia (dogs)
** ROlHL-16901-05 Multipolar linkage between heart
geometry and surface (human, dogs)
P60HL- 17269-04 0027 National heart and blood vessel
research and demonstration center - Non-invasive
evaluation of cardiac function-lschemic heart disease
(human, dog)
** ROlHL-1 7532-04 Infarct size -ECG, angio, path, correlation
in dogs
ROlHL-17604-03 Wearable blood pressure and ECG
recording system
P50HL-17646-04 0001 Study of ischemic heart disease -
Core clinical investigation unit
** P50HL-1 7648-04 0016 Study of ischemic heart disease -
Intraventricular conduction -Effect of pacing on conduction
and automaticity
** P50HL-1 7648-04 0018 Study of ischemic heart disease -
Myocardial damage-Infarction vectors recalled by
premature atrial stimulation
** P50HL-17648-04 0033 Study of ischemic heart disease -
Data management -Electrocardiographic analysis system
P50HL-1 7651-04 0022 Ischemic heart disease specialized
center of research - Electrophysiology-Mechanism and
pharmacology of arrhythmias (human, dog)
P50HL-17651-04 0023 Ischemic heart disease specialized
center of research - Development of multipurpose catheter
for monitoring and electronic pacing
** P50HL-17667-04 0018 Study of ischemic heart disease -
Arrhythmias in ischemic heart disease (human)
** P50HL-1 7667-04 0029 Study of ischemic heart disease -
Computer diagnosis of cardiac arrhythmias after open
heart surgery (human)
P50HL- 1766 7-04 0030 Study of ischemic heart disease -
Computerized clinical data acquisition and processing
** P50HL-17669-04 0013 Ischemic heart disease center
(SCOR) - Exercise in patients v»ifh ischemic heart disease
** P50HL-17670-04 0005 Study of ischemic heart disease -
Quantitative assessment of the vectorcardiogram (human)
** P50HL-1 7670-04 0018 Study of ischemic heart disease ■
Core electrocardiogram laboratory (human)
** ROlHL-17931-04 Normalized body surface potential maps
(children)
** ROlHL-18144-03 Preprocessor system for cardiograms
(human)
ROlHL-18398-04 Mechanisms of delayed and asymetric
ventricular conduction (human, dogs)
R01HL-18517-03 Intrinsic innervation of the heart (dogs)
260
ROlHL-18683-03 Left ventricle function in aortic
regurgitation (human)
ROlHL-1880004 Prospective study of resuscitated sudden
death victims (human)
** ROlHL-18850-03 Classification code for Frank orthogonal
ECG
ROlHL-1921603 Characterization of cardiac pacemaker
activity (cat, dog, rabbit)
" ROlHL-19768-02 Recording and analysis of low levels
cardiac signals (human, dogs)
** ROlHL-20273-02 Cardiac fiber direction and the QRS
complex (dogs)
** ROlHL-20597-02 Electrophysiologic correlates of
myocardial ischemia (human, dogs, rabbits)
** ROlHL-21283-02 Simulation studies of the ECG in acute
ischemia (and human)
" R23HL-21292-01 Human ventricular activation-Patterns
and mechanisms (human)
ROlHL-21527-01 Prospective study of bundle branch block
(human)
** ROlHL-21710-01 Electrocardiographic methods of
quantifying infarct size (human, dogs)
** ROlHL-21750-02 Electrocardiographic quantification of
infarct size (dogs, human)
** NOlHV-429 11-07 ECG center for prevention of coronary
heart disease (human)
** NOlHV-52941-04 Center for aspirin-myocardial infarction
study (human)
** NOlHV-72949-03 ECG center for proprancolo heart trial
HEART DISORDERS DIAGNOSIS,
ELECTROCARDIOGRAPHY FREQUENCIES*
P50HL-17648-04 0018 Study of ischemic heart disease -
Myocardial damage-Infarction vectors recalled by
premature atrial stimulation
P50HL- 17648-04 0021 Study of ischemic heart disease -
Biventricular contractile responses to acute myocardial
infarction (mammals)
HEART DISORDERS DIAGNOSIS,
ELECTROCARDIOGRAPHY MONITOR*
** ROlHL-07575-15 Analysis of time-coherent cardiovascular
data
** POlHL-11310-12 0077 Mechanisms of cardiovascular
disease - Abnormalities of rhythm and conduction following
heart surgery (human)
ROlHL-15790-06 follow-up study of acute coronary heart
attacks (human)
** ROlHL-20632-02 An optimal fetal heart monitor (human)
HEART DISORDERS DIAGNOSIS,
ELECTROCARDIOGRAPHY MONITOR,
ELECTROCARDIOCORDER*
ROlHL-07776-15 Sudden death and cardiac arrhythmias
(human, dogs, cats)
P50HL-17648-04 0033 Study of ischemic heart disease -
Data management -Electrocardiographic analysis system
P50HL- 176 70-04 0012 Study of ischemic heart disease -
Epidemiology of sudden death (human)
ROlHL-18776-04 Prevention of acute and fatal
cardiovascular disease (human)
ROlHL-18783-04 Detection and control of ventricular
premature beats (human)
** R01HL-18808-04 0001 Prediction and prevention of
sudden cardiac death - Prognostic significance of
premature ventricular contractions (human)
** ROlHL-18808-04 0003 Prediction and prevention of
sudden cardiac death - Technical support (computer)
HEART DISORDERS DIAGNOSIS, PICK METHOD*
ROlHL-18683-03 Left ventricle function in aortic
regurgitation (human)
HEART DISORDERS DIAGNOSIS, HEART
CATHETERIZATION*
POlHL-04664-18 0015 Cardiovascular and lung dynamics
- Computer system for the cardiovascular laboratory
POlHL-06285-18 0157 Cardiovascular-respiratory
physiology and biochemistry - Left ventricle outflow
impedance analysis (human)
P01HL-063 12-17 0015 Surgical cardiology - Internal
mammary artery versus saphenous vein for coronary artery
bypass (human)
POlHL-1 13 10-12 0077 Mechanisms of cardiovascular
disease - Abnormalities of rhythm and conduction following
heart surgery (human)
POlHL-1 13 10-12 9002 Mechanisms of cardiovascular
disease - Core support-centralized electronic laboratory
** ROlHL-12307-08 Non surgical treatment of congenital
heart disease (human, dogs)
** POlHL-12373-10 0020 Cardiopulmonary physiology and
pathophysiology - Hospitalization and patient care
POlHL-151 94-07 0001 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation, venous
drainage and collateral flow (human, dogs)
ROlHL-16260-04 Development of clinical cine ultrasound
cardiography
** P60HL-17269-04 0026 National heart and blood vessel
research and demonstration center - Dynamics of ischemic
heart disease (human, dog)
P50HL-1 7651-04 0002 Ischemic heart disease specialized
center of research - Reduction of myocardial ishemic injury
by pharmacologic agents (human, dog)
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"•Oriented significantly to above subject.
M Grant has subprojects describing s
See Appendix for investigator's name
HEA
** P50HL-17651-04 0023 Ischemic heart disease specialized
center of research - Development of multipurpose catheter
for monitoring and electronic pacing
PSOHL-17651-04 0037 Ischemic heart disease specialized
center of research - Measurement of coronary venous
outflow by thermodilution (human)
P50HL-1 7651-04 0048 Ischemic heart disease specialized
center of research - Non-invasive detection of ischemic
heart disease
** P50HL- 17667-04 0039 Study of ischemic heart disease
Core human investigative laboratories
ROIHL- 18683-03 Left ventricle function in aortic
regurgitation (human)
R01HL-19537-03 Detection of myocardial injury with
ultrasound (dogs)
ROlHL-19567-03 Impact of emotion on coronary arteries
(human)
ROlHL-19768-02 Recording and analysis of low levels
cardiac signals (human, dogs)
ROlHL-20630-03 Development of a pulsed Doppler velocity
detector (human, animals)
ROlHL-21985-01 Videoroentgenography in congenital heart
disease
R23HL-22787-01 Cardiac volume by biplane
echocardiography (human)
HEART DISORDERS DIAGNOSIS, HEART SOUND
MEASUREMENTS*
ROlHL-17909-04 Drug treatment of vascular scleroprotein
defects (human, turkeys)
HEART DISORDERS DIAGNOSIS, MYOCARDIAL
INFARCT SIZING
SEE ALSO HEART VISUALIZATION*
POlHL-06308-18 0011 Mechanisms and therapy of
circulatory disease - Blood flow and electrical dysfunction
in ventricular arrhythmia (human)
POlHL-06308-18 0042 Mechanisms and therapy of
circulatory disease - Echocardiographic assessment of
arrhythmias -Myocardial tissue type (human, dogs)
** POlHL-06370-17 0014 Cardiopulmonary and renal
pathology research center - Quantitative morphology in
cardiac disease (human, rats, dogs)
** ROlHL-14571-05 Myocardial preservation and coronary
reperfusion (baboons, dogs)
** ROlHL-17532-04 Infarct size-ECG, angio, path, correlation
In dogs
M P50HL-17646-04 Study of ischemic heart disease
P50HL- 17646-04 0002 Study of ischemic heart disease -
Core data management
P50HL-17646-04 0003 Study of ischemic heart disease -
Core pathology facility (human, dogs)
P50HL- 17646-04 0005 Study of ischemic heart disease -
Biochemical markers and mediators of myocardial ischemic
injury
** P50HL-17646-04 0006 Study of ischemic heart disease -
Mathematical models for predicting infarct size using CPK
and other markers
** P50HL-17646-04 0007 Study of ischemic heart disease -
Prediction of myocardial ischemic injury by analysis of
plasma CPK isoenzymes
P50HL- 17646-04 0009 Study of ischemic heart disease -
Regional metabolic derangements indicating ischemia
(rabbit, dog, human)
P50HL-17665-04 0003 Study of ischemic heart disease ■
Quantitation of injury-Acute myocardial infarction
complicated by shock (human)
** P50HL-17665-04 0011 Study of ischemic heart disease -
Development of new methods for the determination of
infarct size (dog, human)
** P50HL-17665-04 0032 Study of ischemic heart disease -
Myocardial infarct sizing-lmmunoassay for cardiac myosin
light chains (dogs)
P50HL-17667-04 0030 Study of ischemic heart disease -
Computerized clinical data acquisition and processing
** P50HL-17667-04 0043 Study of ischemic heart disease -
Quantitation of myocardial infarct size by serial enzyme
measurements (human)
P50HL-1 7667-04 0045 Study of ischemic heart disease ■
Pathology of myocardial ischemic necrosis (human)
P50HL-1 7669-04 0001 Ischemic heart disease center
(SCOR) - Radioimmunoassays for CPK isoenzyme and
myoglobin (human, dog)
** P50HL-17669-04 0002 Ischemic heart disease center
(SCOR) - Myocardial infarction sizing by radioimmunoassay
of cardiac myosin (dogs)
** P50HL-17669-04 0009 Ischemic heart disease center
(SCOR) - Infarct volume-99Tc stannous pyrophosphate
myocardial scintigrams (dogs, human)
P50HL-17669-04 0022 Ischemic heart disease center
(SCOR) - Pathological studies of human and experimental
ischemic heart disease
** P50HL-17669-04 0023 Ischemic heart disease center
(SCOR) - Patients with acute myocardial infarction and
myocardial ischemia (human)
** P50HL-17670-04 0021 Study of ischemic heart disease -
Enzymatic evaluation of acute myocardial infarction (dogs)
P50HL-1768204 0011 Study of ischemic heart disease -
Nuclear medicine core unit (human, dogs, rabbits, mice)
P50HL-17682-04 0012 Study of ischemic heart disease -
Pathology core laboratory (human)
ROlHL-17809-04 Effects of exercise on the coronary
vasculature (rat, dog)
(oontd)
pecific research aspects,
and grant number.
4
HEA
ROIHL 20648 01 Physiol tactois and coronary How (dogs)
R01HL21684 02 0001 Rsdionuclide mtatct suing and
therapy evaluation Evaluating preservation ol ischemic
myocardium by radioisotope methods (dog)
R01HL2168402 0002 Radionuclide inlaict si/ing and
therapy evaluation Evaluating myocardial imaging agents
In global and regional ischemia (rabbits)
R01HL2168402 0003 Radionuclide infarct sizing and
therapy evaluation Core pathology laboratory (dogs,
human)
ROIHI 21684 02 0004 Radionuclide infarct sizing and
therapy evaluation Image analysis- Kinetics of infarction,
ventricular function (human, animal)
ROIHL 2168402 0005 Radionuclide infarct sizing and
therapy evaluation Clinical evaluation of radioisotope
imaging methods for quantifying infarct size
ROlHL-2169002 Sequential multinuclide study of acute
infarction (human, dogs)
*• R01HL2169701 Myocardium infarct sizing by 82Rb
emission tomography (dogs, human)
•* ROlHl-2170701 Quantification of infarct size by emission
tomography (human, dogs)
** ROlHL-217 10-01 Electrocardiographic methods of
quantifying infarct size (human, dogs)
•* ROlHl-2171901 Computed cardiac tomography in infarct
sizing (dogs, human)
ROlHL-21750-02 Electrocardiographic quantification of
infarct size (dogs, human)
ROlHL-2175102 Thallium and antimyosin in ischemia and
infarction
ROIHL 21793-02 Functional infarct size by gated
radioangiography (human, dogs)
ROlHL-22080-01 Phosphorus NH^R studies on cardiac
tissue (rats, rabbits)
ROlHL-22281-01 Microprobe analysis and metabolite
levels of ischemic mycardium (dogs)
R01HL-22470-01 Liposome myocardial uptake in infarct
and ischemia (dogs, rats, mice)
HEART DISORDERS DIAGNOSIS,
PNEUMOCARDIOGRAPHY*
** ROlHL-22321-01 Cardiac output from the
pneumocardiogram (dogs)
HEART DISORDERS DIAGNOSIS,
POLARCARDIOGRAPHY*
** ROlHL-21750-02 Electrocardiographic quantification of
infarct size (dogs, human)
HEART DISORDERS DIAGNOSIS,
VECTORCARDIOGRAPHY*
SEE ALSO HEART DISORDERS DIAGNOSIS.
POLARCARDIOGRAPHY*
** ROlHL-07575-15 Analysis of time-coherent cardiovascular
data
** PClHL-07896-15 0062 Environmental biomedical research
program ■ Vectorcardiograms during diving (human, dogs)
POlHL-10436-13 0002 A multidisciplinary study of
congenital heart disease ■ Myocardial performance,
metabolism and ultrastructure (human, cats, rats)
POlHL-1 1310-12 0093 Mechanisms of cardiovascular
disease - Multiple dipole electrocardiogram project (human,
dogs)
** ROlHL-16403-05 Prognostication by computer-Analyzed
vectorcardiogram (human)
P50HL-1 7669-04 0013 Ischemic heart disease center
(SCOR) - Exercise in patients with ischemic heart disease
** P50HL-17570-04 0005 Study of ischemic heart disease -
Quantitative assessment of the vectorcardiogram (human)
P50HL-1 7670-04 0018 Study of ischemic heart disease -
Core electrocardiogram laboratory (human)
ROlHL-18850-03 Classification code for Frank orthogonal
ECG
** R23HL-21292-01 Human ventricular activation-Patterns
and mechanisms (human)
** ROlHL-21750-02 Electrocardiographic quantification of
infarct size (dogs, human)
HEART DISORDERS DIAGNOSIS, VECTOR
MAGNETOCARDIOGRAPHY*
" ROlHL-09831-12 Effect of resistivity variations on
electrocardiogram (human)
ROlHL-18398-04 Mechanisms of delayed and asymetric
ventricular conduction (human, dogs)
HEART ENLARGEMENT
SEE HEART DISORDERS. HEART ENURGEMENT
HEART EXAMINATIONS
SEE HEART DISORDERS DIAGNOSIS (INCL EXAMS)*
HEART FAILURE
SEE HEART DISORDERS. HEART FAILURE
HEART FAILURE, CONGESTIVE
SEE HEART DISORDERS. HEART FAILURE. CONGESTIVE
HEART FUNCTION
SEE ALSO HEART DISORDERS DIAGNOSIS,
BALLISTOCARDIOGRAPHY*
SEE ALSO HEART DISORDERS DIAGNOSIS. FICK METHOD*
SEE ALSO HEART DISORDERS DIAGNOSIS.
PNEUMOCARDIOGRAPHY*
261
ROIHI 00487 29 Vasomotor tone and venous return
(human, dogs, monkeys )
ROIHL 01486 23 Quantitative study of T vnave mechanisms
(human, rabbits, dogs, chickens)
• R01HL0175525 Fetal and neonatal cardiovascular
function (sheep)
ROIHL 03181 21 0020 Hemodynamics as applied to
surgical problems Blood How measurement Cardiac
output and regional flows (dogs)
ROIHL 03181 21 0025 Hemodynamics as applied to
surgical problems Vascular stenosis (dogs)
« POIHL 04664 18 Cardiovascular and lung dynamics
•* POIHL 04664 18 0010 Cardiovascular and lung dynamics
Left ventricular dynamics (human)
'* P01HL04664 18 0013 Cardiovascular and lung dynamics
Ventricular function in coronary disease using NTG and
ventriculograms (human)
** R01HL04666 19 Artificially paced hearts Technology.
physiology (human, dogs)
** ROIHL 05R83 18 0006 Reflex control of resistance and
capacitance vessels Cardiopulmonary vagal afferents in
the conscious dog
** ROlHL-06143-18 Response of the totally denervated heart
to exercise (dogs)
M P01HL0628518 Cardiovascular-respiratory physiology and
biochemistry
** POlHL-06285-18 0125 Cardiovascular-respiratory
physiology and biochemistry - Myocardial function in the
fetal and neonatal lamb
POlHL-06285-18 0131 Cardiovascular respiratory
physiology and biochemistry - Fetal heart development and
ventricular outflow obstruction (lambs)
POlHL-06285-18 0133 Cardiovascular-respiratory
physiology and biochemistry - Decreased uterine blood flow
and fetal development (lambs)
** POlHL-06285-18 0154 Cardiovascular-respiratory
physiology and biochemistry - Function and viability of
critically ischemic myocardium (dogs)
** POlHL-06285-18 0156 Cardiovascular-respiratory
physiology and biochemistry - Myocardial performance
following revascularization (human)
** POlHL-0628518 0158 Cardiovascular-respiratory
physiology and biochemistry - Load on myocardial
contractility (dogs)
M POlHL-06296-18 Cardiovascular and pulmonary
adaptation to stress
Cardiovascular and pulmonary
Human exercise studies (human,
POIHL 08899 14 0010
health and disease
(human)
POIHL 08899 14 0025
health and disease
HEA
Tolerance to respiratory gasei in
High oxygen pressure in septic shock
Cardiovascular and pulmonary
- Regulation of ventricular
** POlHL-06296-18 0003
adaptation to stress
dogs)
** POlHL-06296-18 0005
adaptation to stress
performance (animals)
M POlHL-06308-18 Mechanisms and therapy of circulatory
disease
POlHL-06308-18 0025 Mechanisms and therapy of
circulatory disease - Subcellular calcium pools in the
genesis of arrhythmias (dogs)
POlHL-06312-17 0016 Surgical cardiology - Effect of
hydralazine on infarct size following coronary occlusion
(human)
" POlHL-063 12-17 0025 Surgical cardiology - Effect of
denervation on arrhythmias and function with coronary
occlusion (dogs)
POlHL-0631217 0030 Surgical cardiology - Total
artificial heart (calves)
** P01HL063 1217 0034 Surgical cardiology - Metabolic
factors in cardiac function-Creatine phosphate depletion
(animals)
** POlHL-06312-17 0036 Surgical cardiology - Experimental
studies of cardiac compliance (dogs)
** POlHL-063 12-17 0044 Surgical cardiology - The limits of
topical cardiac hypothermia with ice chips (rats)
** POlHL-06312-17 0046 Surgical cardiology - The
relationship of prostaglandins to heart disease
POlHL-063 12-17 0048 Surgical cardiology - Use of an
adjustable pulmonary artery band (dogs)
POlHL-063 12-17 0052 Surgical cardiology - Assay of
metabolic variables of rat heart
** POlHL-06835-17 0041 Cardiovascular disease ■ Cardiac
performance in rats with renal hypertension
** POlHL-06835-17 0042 Cardiovascular disease -
Myocardial hypertrophy due to renal hypertension (rats)
POlHL-06835-17 0044 Cardiovascular disease -
Baroreceptors in control of blood pressure during sleep
(dogs)
POlHL-06835-17 0057 Cardiovascular disease - Studies
on cardiac hypertrophy
** R01HL06924-16 Humoral and metabolic aspects of
cardiac function (mammals, non-human, human)
ROlHL-07723-15 Reflex control of vascular capacitance in
shock
ROlHL-08659-14 Myocardial performance and metabolism
in the newborn (sheep)
POlHL-0868215 Regulation of the cardiovascular system
POlHL-08682-15 0006 Regulation of the cardiovascular
system - Cardiovascular studies of mammalian hibernators
(sciuromorpha)
POlHL-08805-15 Regulation of ventilation and pulmonary
circulation
POlHL-08805-15 0050 Regulation of ventilation and
pulmonary circulation - Right ventricular mechanics (dogs)
M
M
Tolerance to respiratory gaui In
Effects of oxygen on cardiopulmonary
gas transport functions (dogs)
POIHL 08899 14 0064 Tolerance to respiratory gases in
health and disease Narcotic effects of inert gases on
functional systems (rats)
ROIHL 09315 15 Coronary insufficiency and myocardial
revascularization (human, dogs)
ROIHL 09474 11 Natural history congenital heart defects-
Joint study (human)
ROIHL 09476 10 Natural history, congenital heart defects-
Joint study
ROIHL 09489 13
regulation (rats)
ROIHL 09914 13
(dogs, monkeys)
ROIHL 10330 11
Myocardial lipid metabolism and
The myocardium in diabetes mellitus
Physiological mechanics of the heart and
arteries (dogs, rabbits, horses)
POIHL 10342 13 0026 The integrated function of
respiration and circulation Control of respiration
Characterization of the aortic body (cats)
* POIHL 10436 13 0002 A multidisciplinary study of
congenital heart disease Myocardial performance,
metabolism and ultrastructure (human, cats, rats)
/I POlHL-10539-12 Pathophysiology of circulation
'* POIHL 10539-12 0068 Pathophysiology of circulation
Acute and chronic cardiomyopathies (mice, dogs, hamsters,
human)
'* POIHL 10539-12 0069 Pathophysiology of circulation -
Ventricular compliance and mechanics in intact ventricles
(human)
R01HL10718-10 Natural history of congenital heart
defects-Joint study (human)
ROlHL-10942-09 Study of genetic hypertension in rats
M POlHL-11310-12 Mechanisms of cardiovascular disease
** POlHL-11310-12 0063 Mechanisms of cardiovascular
disease - Myocardial function, metabolism and cellular
integrity after heart surgery (dogs)
POlHL-11310-12 0065 Mechanisms of cardiovascular
disease - Algorithms for arterial pressure by automatic
vasoactive agents control (human)
POlHL-1 1310-12 0068 Mechanisms of cardiovascular
disease - Pharmacological intervention and myocarcial
oxygen consuption (human, dogs)
** POlHL-11310-12 0081 Mechanisms of cardiovascular
disease - Analysis of regional left ventricular function
(human)
** POlHL-1 1310-12 0082 Mechanisms of cardiovascular
disease - Myocardial function in adult congenital heart
disease (human)
*• POlHL-11310-12 0084 Mechanisms of cardiovascular
disease - Evaluation of cardiac function in chronic renal
failure (human)
** POlHL-11310-12 0094 Mechanisms of cardiovascular
disease - Physics of pulsatile fluid flow (dogs)
POlHL-11351-12 0002 Cellular and molecular
mechanisms of myocardial function - Effects of hypoxia
and ischemia on ionic exchange (rats, rabbits)
** POlHL-11351-12 0015 Cellular and molecular
mechanisms of myocardial function - Effects of hypoxia
and ischemia on ion exchange and heart function (rabbits)
** POlHL-11351-12 0018 Cellular and molecular
mechanisms of myocardial function - Quantitative
localization of electrolytes in cardiac tissue
** ROlHL-11906-11 Comparative study of heart function
(cats, rats, hedgehogs, squirrels)
** ROlHL-12322-10 Extrinsic factors influencing myocardial
performance (dogs, swine)
M POlHL-12373-10 Cardiopulmonary physiology and
pathophysiology
POlHL-12373-10 0002 Cardiopulmonary physiology and
pathophysiology ■ Determinants of performance of the
whole heart (dogs)
** POlHL-12373-10 0005 Cardiopulmonary physiology and
pathophysiology ■ Characterization of fetal and neonatal
myocardium (human, cats)
** POlHL-12373-10 0013 Cardiopulmonary physiology and
pathophysiology - Effects of cardiovascular drugs on left
ventricular function (dogs)
POlHL-1237310 0020 Cardiopulmonary physiology and
pathophysiology - Hospitalization and patient care
** ROlHL-1241510 Evaluation of left ventricular function
(dogs, rabbits)
R01HL-12542-07 Natural history, congenital heart defects-
Joint study (human)
ROlHL-12607-10 Dynamics of pulsatile blood flow (human.
dogs, rats)
ROlHL-12611-10 Basic and clinical studies of the ST-T
deflection (human, dogs)
ROlHL-12690-09 Systemic and local vascular adjustment
in shock (monkeys, cats)
ROlHL-12711-09 Mathematical approach to cardiovascular
mechanics (human, animals)
M POlHL-1273810 Physiologic pharmacology and its clinical
applications
POlHL-12738-10 0069 Physiologic pharmacology and its
clinical applications - Blood rheology in coronary heart
disease (dogs)
(contd)
•Excludes routine methodology OR covers only general projects which preclude
"Ofiented significantly to above subject.
Indexing at the specific level.
M Grant has subprajects describing specific research aspects.
See Appendix for investigator's name and grant number.
HEA
POlHL-12738-10 0071 Physiologic pharmacology and its
clinical applications - lABP patient management in
ventricular power failure (human)
POlHL-12738-10 0094
clinical applications -
(human, dogs)
POlHL-12738-10 0108
clinical applications
Physiologic pharmacology and its
Ventricular function and structure
Physiologic pharmacology and its
Developmental electrophysiology and
pharmacology (human, animals)
POlHL-12738-10 0133 Physiologic pharmacology and its
clinical applications - Pharmacologic antagonism of beta-
adrenergic blockade (dogs)
POlHL-1273810 0134 Physiologic pharmacology and its
clinical applications - Adenylate cyclase and cAMP
phosphodiesterase in cardiac development (dogs)
P01HL12738-10 0135 Physiologic pharmacology and its
clinical applications - Myocardial cells in tissue culture
(rats, chick embryo)
R01HL12777-09 Mechanisms in cardiac performance
(dogs, human)
POlHL-13108-09 0008 Clinical heart transplantation -
Physiology and pharmacology of the transplanted human
heart
R01HL13233-08 Cardiorespiratory control in exercise
(human)
ROlHL-13257-09 Inhalation anesthesia on myocardial
metabolism (dogs, swine, human)
ROlHL-13426-09 Left ventricular bypass for myocardial
infarction (cattle, human)
ROlHL-13454-08 Behavioral stress and cardiomyopathy
(monkeys, cats)
POlHL-13480-09 0042 Cardiac electrophysiology -
Computer modeling of arrhythmias
ROIHL' 13636-08 Effects of pharmacologic agents on heart
metabolism (human, rodents)
' ROlHL-13639-07 Factors altering the course of myocardial
dysfunction (cats)
■ POlHL-13737-07 0007 Assisted circulation -
Determination of cardiac status by use of balloon pump
(dogs)
POlHL-13737-07 0013 Assisted circulation - Incorporation
of sensors (human, dogs)
POlHL-1373707 0027 Assisted circulation - Optimization
of cardiac assistance (dogs)
POlHL-13737-07 0034 Assisted circulation - Phasic aortic
flow and cardiac output from phasic pressures (dogs)
P01HI.-1373808 0001 Cardiac assist devices and
artificial hearts - Cardiac assist devices (human, sheep)
POlHL-13738-08 0002 Cardiac assist devices and
artificial hearts - Total replacement with artificial heart
(calves, sheep, ponies)
ROlHL-13920-07 Expanding the role of surgeiY of atrial
dysrhythmias (dogs)
R01HL14102-07 Human physiology at 5360 meters-
Mountain environment
P50HL-14164-07 0032 A/S SCOR-Comparative and
experimental atherosclerosis - Plasma cholesterol, lesion
regression and vascular function (Rhesus monkey)
P50HL-14164-07 0042 A/S SCOR-Comparative and
experimental atherosclerosis - Comparative cardiology
laboratory (monkeys)
P50HL-I4236-05 0002 Prevention of premature
arteriosclerosis - Myocardial blood flow in patients with
coronary artherosclerosis
P01HL14388-07 0214 Regulation of the circulation in
pathological states - Deformation pattern and stress
analysis of the left ventricle
P01HL14388-07 0215 Regulation of the circulation in
pathological states - Left ventricle model in
pathophysiologic states
POlHL-14388-07 0216 Regulation of the circulation in
pathological states - Development and regression of
ventricular hypertrophy (cats, rats)
POlHL-14388-07 0219 Regulation of the circulation in
pathological states - Myocardial Ischemia and infarction in
animals (dogs)
POlHL-14414-07 Environmental influences on
cardiorespiratory and cellular functions
POlHL-1441407 0008 Environmental influences on
cardiorespiratory and cellular functions ■ Energetics of
swimming (human)
Mechanical behavior of left ventricle
Fetal hearts in organ culture (mice)
Hypothermia and the heart (bats, guinea
Lung and tissue mechanics (monkeys,
ROlHL-14651-05
(dogs, rats)
ROlHL-14706-07
ROlHL-14713-06
pigs)
R0IHL14854-07
dogs)
R01HL-lS416-0e Cardiovascular control in normal and
disease states (dogs, baboons)
ROlHL'15430-05 Cardiopulmonary adaptation of newborns
to altitude (human)
R01HL15498-06 Effects of physical training on heart
(rats)
R01HL15622-05
dogs)
R01HL15696-06
heart (animals)
R01HL15799-04
function (cats)
R01HL15813-05
Computer simulation in cardiology (rats.
Mechanism and role of cyclic GMP in
Effect of anesthetics on myocardial
Cardiac anoxia-Protective effect of
carbohydrate (dogs)
262
R01HL15837-06 Renin and cardiac hypertrophy in
hypertension (rats)
ROlHL-16154-05 Membrane lung perfusion for acute
respiratory failure (sheep, baboons)
R01HL16292-05 0002 Surgery and non-obstructive
coronary insufficiency - Effects of hypothermia during
cardiopulmonary bypass (dogs)
ROlHL-16292-05 0009 Surgery and non-obstructive
coronary insufficiency - Exercise and supply-demand
balance (human)
ROlHL-16292-05 0018 Surgery and non-obstructive
coronary insufficiency - Unavoidable subendocardial
perfusion caused by venting and hypothermia (dogs)
ROlHL-16329-04 (Cardiac surgical effect on heart function
in infants (human)
ROlHL-16420-02 Effect of training-detraining on the rat
heart
ROlHL-16484-04 Radiographic ventricuiometry for coronary
heart disease (human)
ROlHL-16487-05 Computer controlled two dimensional
echocardiography
ROlHL-16648-16 Integrated control of cardiovascular
activity (cats)
ROIHL 16908-04 Myocardial function, risk factors and
future CHD (men)
ROlHL-16909-04 Myocardial function, risk factors and
future CHD (men)
ROlHL-16935-05 Tissue organization and turnover in the
semilunar valve (dogs, rats)
P60HL-17269-04 0024 National heart and blood vessel
research and demonstration center - Section of
experimental cardiovascular surgery-Core facility
ROlHL-17370-03 Synaptic chemistry and cardioregulafion
in Limulus
ROlHL-17372-03 Adenine nucleotide maintenance in the
ischemic heart (rats)
ROlHL-17401-03 Mechanisms in angiotensin induced
hypertension (cats, dogs)
ROlHL-17503-03 Vascular bubbles in decompression
sickness (minipig. dog, goat)
ROlHL-17516-04 Role of androgen as a risk factor in
atherogenesis (human, animals)
R01HL-17578-04 Exercise performance in children with
heart disease
P50HL- 17648-04 0012 Study of ischemic heart disease -
Retrograde coronary venous perfusion-Acute myocardial
Ischemia
P50HL-17648-04 0020 Study of ischemic heart disease ■
Core pathology laboratory-lschemic heart disease (human,
animal)
P50HL-17651-04 0046 Ischemic heart disease specialized
center of research - Clinical core-Physiological
changes/biochemical effects of myocardial ischemia
P50HL-17655-04 0001 Study of ischemic heart disease -
Intravenous nItroglycerin-Ventricular function and infarct
size (human, dog)
P50HL-17655-04 0004 Study of ischemic heart disease -
Coronary arteriography in survivors of acute myocardial
infarction (human)
P50HL-17655-04 0009 Study of ischemic heart disease -
Random trial of medical and surgical therapy in unstable
angina (human)
P50HL-17665-04 0001 Study of ischemic heart disease -
Reduction of acute anterior myocardial infarction-
Mechanical circulatory assist
P50HL- 17665-04 0002 Study of ischemic heart disease -
Reducing acute anterior myocardial infarction-Beta
adrenergic blockade (human)
P50HL- 17665-04 0005 Study of ischemic heart disease -
Evaluation of zone of jeopardized myocardium in patients
with angina pectoris
P50HL-17665-04 0012 Study of ischemic heart disease -
Myocardial ischemia-Cardiovascular performance in the
conscious baboon and dog
P50HL-17665-04 0013 Study of ischemic heart disease -
National cooperative study in unstable angina pectoris
(human)
P50HL- 1 7665-04 0020 Study of ischemic heart disease -
Ischemic injury to myocardium during measured states of
ischemia (human)
P50HL-17665-04 0021 Study of ischemic heart disease -
Identification, prevention-Myocardial ischemia in
cardiopulmonary bypass (dog)
P50HL-17665-04 0022 Study of ischemic heart disease -
Effect of coronaor revascularization on left ventricular
function (human)
P50HL- 176 65-04 0028 Study of ischemic heart disease -
Pathologic and biochemical studies of ischemic
myocardium (human, dog)
P50HL- 17667-04 0042 Study of ischemic heart disease -
Core-Central instrumentation and software
P50HL- 176 69-04 0006 Ischemic heart disease center
(SCOR) - Studies of hypoxic, acidotic and ischemic cardiac
muscle (dogs)
P50HL-17670-04 0009 Study of ischemic heart disease -
Surgical treatment of localized left ventricular dyssynergy
(human, dogs)
P50HL-17682-04 0001 Study of ischemic heart disease -
Studies in acute and chronic ischemic heart disease
(human)
P50HL-17e82-04 0003 Study of ischemic heart disease -
Effects of myocardial revascularization in man
*E>cludes routine methodotogy OR covers only general projects which preclude indexing at the specific level.
"Oriented significarrtly to above subject
HEA
P50HL-17682-04 0008 Study of ischemic heart disease -
Clinical core unit
P50HL- 17682-04 0009 Study of Ischemic heart disease -
Computer core unit
P50HL-1 7682-04 0011 Study of ischemic heart disease ■
Nuclear medicine core unit (human, dogs, rabbits, mice)
P50HL-17682-04 0013 Study of ischemic heart disease •
Chronic ischemic heart disease-Myocardial function and
metabolism (dogs, swine)
P50HL- 17682-04 0015 Study of ischemic heart disease -
Acute myocardial ischemia and infarction and their
reversibility (dogs, baboons)
P50HL-17682-04 0016 Study of ischemic heart disease -
Endurance exercise-Prevention and rehabilitation in
ischemic heart disease (pig)
ROlHL-17732-03 Peripheral venomotor control in thermal
stress (human)
ROlHL-17799-02 The presence and significance of heart
acetylcholine (cats)
POlHL-17812-04 0007 Thrombosis and plasma proteins -
Blood components-Response to endotoxin (dogs, baboons)
POIHL- 178 13-04 0007 Lung disease and the oxygenation
of blood and tissue - Studies on the function of myoglobin
(dogs)
ROlHL-17859-04 Computational methods In cardiac fluid
dynamics
ROIHL- 17895-04 Myocardial function and metabolism
following ischemia (rats)
ROlHL-17970-04 Vascular effects of inhibitory behavioral
adaptations (dogs)
ROlHL-17993-04 Ventricular dynamics from surgically
inserted markers
ROIHL 17993-04 0001 Ventricular dynamics from
surgically inserted markers - Effects of aortocoronary
bypass graft surgery on ventricular function (human)
ROIHL- 17993-04 0002 Ventricular dynamics from
surgically inserted markers - Left ventricle function in
human cardiac allograft
ROIHL- 17993-04 0003 Ventricular dynamics from
surgically inserted markers - Effects of pharmacologic
agents on left ventricular dynamics (human)
ROIHL 17993-04 0004 Ventricular dynamics from
surgically inserted markers - Exercise training following
coronary artery bypass graft surgery (human)
ROlHL-17993-04 0005 Ventricular dynamics from
surgically inserted markers - Cardiac dimensions and
dynamic after mitral, aortic valve surgery (human)
ROlHL-17993-04 0006 Ventricular dynamics from
surgically inserted markers - Atrial pacing in transplant
patients
ROIHL- 17993-04 0007 Ventricular dynamics from
surgically inserted markers - Digitalis after coronary artery
surgery (human)
ROlHL-17993-04 0008 Ventricular dynamics from
surgically inserted markers - Exercise after coronary bypass
(human)
ROIHL- 17993-04 0010 Ventricular dynamics from
surgically inserted markers - Postoperathre cardiovascular
visualization (human)
ROlHL-18024-03 Regional myocardial flow and function
relationships (dogs)
ROlHL-18060-04 Exercise and coronary atherosclerotic
heart disease (monkeys)
ROlHL-18096-04
(primates, dogs)
ROlHL-18144-03
(human)
ROlHL-18288-04 Intraoperative protection of the
myocardium (dogs, rats)
ROlHL-18371-03 Pulmonary hypertension and ventilation
pathophysiology (dogs)
ROlHL-18460-01 Effects of prolonged hypoperfusion on the
myocardium (rabbits)
ROlHL-18560-03 Cardiovascular adaptation to stress
(miniature swine)
P01HL18646-03 0010 Studies basic to heart
transplantation - Development and study of a heart
preservation chamber (dogs, sheep)
R01HL-18e83-03 Left ventricle function in aortic
regurgitation (human)
ROlHL-18731-02 RES stimulating materials in
experimental shock (dogs)
ROIHL 18769-04 Studies in survivors of lethal arrtiythmias
(human)
ROlHL-18805-04 0003 Sudden cardiac death and the
onset of myocardial infarction - Prediction from clinical and
laboratory assessments (human)
ROlHL-18805-04 0004 Sudden cardiac death and the
onset of myocardial infarction - Sudden death survivors-
Clinical follow-up and therapy (human)
ROlHL-18805-04 0005 Sudden cardiac death and the
onset of myocardial infarction < Sudden death survivors-
Radionuclide studies (human)
ROlHL-18805-04 0007 Sudden cardiac death and the
onset of myocardial infarction - Analysis of pathologic
factors involved in sudden death (human)
ROlHL-19030-03 Tissue protection during circulatory
interruption (dogs)
ROlHL-19135-04 Heterogeneity of regional myocardial
blood flow (dogs)
ROlHL-19181-02 Regulation of heart cAMP-dependent
protein kinase (rodents)
(contd)
Vasoactive agents in splanchnic viscera
Preprocessor system for cardiograms
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
v<--V:
^1
HfA
R0lHL'19l(2'O3 Suiglcil aspects ot niyocaidial
hypartrophy (do|s)
ROIHI 19203 03 Surjic»l approach to contenilal heart
diseases (dogs, phmates)
M ROIHI 19225-02 Types and mechanims ot pulmonary
hypertension
•• ROIHL 1922502 0003 Types and mechanims ot
pulmonary hypertension Caidiopulmonaiy tunction in pigs
and lats
** ROIHL 19257 03 Catdiovascular adjustment to behavioral
stress (dog)
•• R01H11936603 Renal Starling forces in experimental
conditions (rats, rabbits)
ROIHI 1937403 Pharmacology ot kinins in cardiovascular
disease (rats, rabbits)
ROIHL 1941403 Protection of myocardium during cardiac
surgery (dogs. cats, human)
** R01HL19425-03 Cardiac function in hypertrophy (dog)
** R23HL1960101 Cardiac response to chronic metabolic
acidosis (rats)
ROIHL 1967801 Quantification of intrathoracic fluid by
impedance (human, dogs)
ROIHL 19782 02 Pharmacologic studies on the ischemic
heart (dogs)
R01HL1993702 Vasodilators in experimental myocardial
infarction (dogs)
R01HL1997702 Genesis of circulatory shock by
pancreatic peptides (cats, dogs)
*• ROlHL-20080-02 Surgically induced myocardial edema
(dogs)
•• ROlHL-20190-02 Pathogenesis of cardiac hypertrophy
(dogs)
ROlHL-20211-02 Role of taurine in the heart (dogs, rats.
mice)
ROlHL-20230-02 Analysis of the action potential of
cardiac muscle (sheep)
** ROlHL-2025302 Effects of exercise on the heart and its
blood supply (dogs)
** ROlHL-20274-02 Gated imaging with the MGH x-ray
camera
" ROlHL-20374-03 Myocardial function-Risk factors and
future CHD (human)
** ROlHL-20476-03 Effects of diabetes on cardiac
performance (rat)
** ROlHL-20484-03 Effects of diabetes on cardiac function
and metabolism (rats)
POlHL-20552-02 9001 The development and regression of
cardiac hypertrophy - Core A-Palhology
M ROlHL-2057202 Hemodynamic relations to metabolism in
hypertension
*♦ ROlHL-2057202 0001 Hemodynamic relations to
metabolism in hypertension • Hemodynamic and myocardial
functional studies in the SHR (rat)
** ROlHL-20572-02 0007 Hemodynamic relations to
metabolism In hypertension ■ Drug effects on cardiac
function and hypertropy (rats)
ROlHL-2067702 Radionuclide studies in congenital heart
disease
ROlHL-2067802 Cardiovascular adaptation to stress in
disease states (dogs)
ROlHL-2082902 Fluid mechanics of heart valve
prostheses (dogs, human)
ROlHL-2120902 Alterations of metabolism in ischemic
myocardium (swine)
ROlHL-21293-02 Randomized study of coronary bypass
surgery (human)
R23HL-21327-02 {Molecular mechanisms of chemical
myocardiopathies (rats)
** R23HL-21368-02 Perinatal cardiac electrophysiology (dogs)
R23HL-2 1462-02 Mechanical interactions between ventricle
arteries (dogs)
** ROlHL-21482-01 Cardiac function and metabolism in
diabetes (rats)
ROlHL-21684-02 0004 Radionuclide infarct sizing and
therapy evaluation - Image analysis -Kinetics of infarction,
ventricular function (human, animal)
ROlHL-21786-01 Long-term effects of myocardial
protection (dogs, rats)
** ROlHL-21985-01 Videoroentgenography in congenital heart
disease
R23HL-22004-0I Imaging and ECG studies in acute and
chronic IHO (human)
ROlHL-22069-02 Experimental renal arterial hypertension
(dogs)
** ROlHL-22154-01 Cardiac adaptation to physical training
(dog)
•* ROlHL-22265-02 Isozymes of heart glutamate aspartate
transaminase (swine, ducks)
ROlHL-22274-01 Quantitating in series effects in cardiac
arrhythmias (dogs)
** ROlHL-22315-01 Intraoperative cardiac oxygen supply-
demand (dogs, rabbits, rats)
** ROlHL-22361-01 Regulation of cardiac adaptation to
exercise (rats)
** ROlHL-22401-01 Regulation of tension and active state in
the heart
** ROlHL-22418-01 Neural control of cardiorespiratory
function (cats)
** ROlHL-22461-01 Cardiac tropomyosin and tropomyosin-
action interactions (rabbit)
*• R23HI.-22490-01 Neurotransmitter receptors of cultured
heart cells
263
*• ROIHL 22801 01 Analysis of coronary irtety behavior
(dogs)
** ROIHL 2281b 01 Regional myocardial function atter
levasculariiation (dogs)
ROIHL 22859 01 Effect of carbon monoxide on the
developing heart (rats)
** ROIHL 22894 01 Two dimensional ultrasound and cardiac
surgery (human, dogs)
*• ROIHL 23206 01 Repetitive exercise and cardiac
enlargement (dogs)
ROIHL 23312 01 Hemodynamics and vasoactivity in renal
hypertension (human, dogs)
N01HV42914 13 Solenoid left ventricular assist system
(cattle)
HEART FUNCTION, CARDIAC OUTPUT
SEE ALSO HEART DISORDERS, OUTPUT ABNORMALITIES
** ROIHL 03181 21 0020 Hemodynamics as applied to
surgical problems Blood flow measurement -Cardiac
output and regional flows (dogs)
P01HL04664-18 0001 Cardiovascular and lung dynamics
X ray prelection image videodensitometry (dogs)
POlHL-0466418 0005 Cardiovascular and lung dynamics
■ Applications of current research, equipment and
techniques
POlHL-04664-18 0009 Cardiovascular and lung dynamics
Biological signal and image processing techniques (dogs)
** P01HL0628518 0126 Cardiovascular-respiratory
physiology and biochemistry - Ventricular output, foramen
ovale and ductus arteriosus flows (lambs)
P01HL06285 18 0146 Cardiovascular-respiratory
physiology and biochemistry Pathogenesis and detection
of hypoxic pulmonary edema (human, animals)
** P01HL06285-18 0157 Cardiovascular-respiratory
physiology and biochemistry - Left ventricle outflow
impedance analysis (human)
POlHL-06285-18 0164 Cardiovascular respiratory
physiology and biochemistry CPK MB isoenzyme
concentration to quantify infarct size (human, animals)
POlHL-06308-18 0011 Mechanisms and therapy of
circulatory disease - Blood flow and electrical dysfunction
in ventricular arrhythmia (human)
POlHL-06835-17 0040 Cardiovascular disease ■ Benign
and malignant phase of renal hypertension (dogs)
** POlHL-06835-17 0051 Cardiovascular disease -
Cardiopulmonary volume in hypertension (human)
POlHL-06835-17 0053 Cardiovascular disease -
Vasodilating drugs (human)
POlHL-06835-17 0059 Cardiovascular disease -
Metyrapone-induced hypertension in dog
** POlHL-06835-17 0060 Cardiovascular disease -
Ventricular performance experimental models of arterial
hypertension (rats, dogs)
POlHL-07293-17 0043 Non-invasive cardiovascular
measurements - ECHO-Doppler instrumentation for cardiac
measurements (human)
POlHL-07293-17 0051 Noninvasive cardiovascular
measurements - Physiologic evaluation of duplex scanner
(dogs)
POlHL-07293-17 0059 Non-invasive cardiovascular
measurements - Intracardiac blood flow measurement
(human)
POlHL-07896-15 0033 Environmental biomedical research
program - Breathing mechanism in birds
POlHL-07896-15 0054 Environmental biomedical research
program - Myocardial effects of hemorrhagic shock (dogs)
POlHL-08682-15 0021 Regulation of the cardiovascular
system - Hypoglycemia in pathogenesis of shock (dog)
** POlHL-08682-15 0023 Regulation of the cardiovascular
system - Cardiovascular control-Effects of spinal pathways
lesions (dog)
POlHL-08682-15 0026 Regulation of the cardiovascular
system - Hypertension -High renin vs low renin (dog)
POlHL-08682-15 0027 Regulation of the cardiovascular
system - Cardiac mechanoreceptors -Reflex regulation of
renal function (dogs)
ROlHL-09154-14 Central control of distribution of organ
blood flow (monkeys)
ROlHL-097 11-13 Instantaneous blood flow in ascending
aorta (human, dogs)
POlHL-10342-13 0008 The integrated function of
respiration and circulation - Respiratory mechanics and the
circulation (human, dogs)
POlHL-10342-13 0028 The integrated function of
respiration and circulation - Mediator release,
hemodynamics and respiratory function in anaphylaxis
(dogs)
ROlHL-10384-13 Blood flow and nucleotide metabolism
(animals)
POlHL-1043613 0001 A multidisciplinarv study of
congenital heart disease ■ Assessment of the outlook for
children with congenital heart disease
P01HL10436-13 0005 A multidisciplinary study of
congenital heart disease ■ Pulmonary physiology in
congenital heart disease (human)
** POlHL-10436-13 0008 A multidisciplinary study of
congenital heart disease - Physiologic consequences of
chronic hypoxemia (human)
POlHL-10436-13 0014 A multidisciplinary study of
congenital heart disease - Cardiovascular pharmacology
(dog)
HEA
Palhophyiiology ot circulation
I ardiomyopathiei (mice. dog», hamtteri.
POIHI IHM I
Acull' .inil
human!
POIHL 10539 1? 00/0 Palhophyiiology of tirculalion
Effects of hypertension on myocardial blood flow after
coronary occlusion (dogs)
* ROIHL 10612 13 0018 Humoral factors in heart failure
and hypertension The pathogenesis of experimental rem!
hypertension (dogs, rabbits, rats)
ROIHL 11152 12 Vascular physiology (human, cats, dogs)
POIHL 11310 12 0055 Mechanisms ot cardiovascular
disease Ventricular pressure volume after intracardiac
surgery (human)
* POIHL 11310 12 0056 Mechanisms ot cardiovascular
disease Cardiac output response to blood pressure
reduction in infants (human)
* P01HL11310 12 0057 Mechanisms of cardiovascular
disease Blood pressure reduction after heart surgery in
adults (human)
P01HL11310 12 0059 Mechanisms of cardiovascular
disease Contractility Acute response to diogoxin after
heart surgery (children)
'• POIHL 11310 12 0062 Mechanisms of cardiovascular
disease Myocardial depressant factor in postoperative
cardiac dysfunction (human, dogs)
'* POIHLI 1310-12 0066 Mechanisms of cardiovascular
disease Measurement of cardiac output by thermodilution
(children)
** POIHL 11310-12 0067 Mechanisms of cardiovascular
disease ■ Cardiac performance with measured
hemodynamic variables (human)
•* POIHL 1131012 0076 Mechanisms of cardiovascular
disease - Tratment of depressed cardiac output following
heart surgery (children, puppies)
POIHL 11310-12 9001 Mechanisms of cardiovascular
disease - Core support-hospital beds
POlHL-11678-11 0020 Cardiovascular dynamics and their
control - Circulatory and pulmonary fluid dynamics during
pulmonary edema
POlHL-l 1678-11 0043 Cardiovascular dynamics and their
control - Basic mechanisms of circulatory shock (dog)
** POlHL-11678-11 0059 Cardiovascular dynamics and their
control Basic hemodynamics (dogs, rats)
POlHL-l 1678-11 0063 Cardiovascular dynamics and their
control - Renin-angiotensin system -Control of renal
hemodynamics, electrolyte excretion
P01HL11678-11 0065 Cardiovascular dynamics and their
control ■ Body fluid volumes in the genesis of hypertension
(dogs) ^ ,^
POlHL-11678-11 0068 Cardiovascular dynamics and their
control ■ Basic hemodynamics (rats, dogs)
POlHL-11678-11 0069 Cardiovascular dynamics and their
control ■ Nervous control of the cirulation (dogs)
ROIHLI 1907-08 Mechanisms of physiological responses
to exercise (human, dogs)
POlHL-12373-10 0005 Cardiopulmonary physiology and
pathophysiology • Characterization of fetal and neonatal
myocardium (human, cats)
R01HL12415-10 Evaluation of left ventricular function
(dogs, rabbits)
P01HL12738-10 0111 Physiologic pharmacology and its
clinical applications ■ Cardiovascular pharmacology (dogs)
'* POlHL-13108-09 0023 Clinical heart transplantation ■
Adaptive mechanisms of the denervated heart (human)
POIHL- 13330-08 0034 Mechanical circulatory support • In
vivo test and evaluation of left ventricular bypass pumps
(human, cattle)
POlHL-13330-08 0059 Mechanical circulatory support -
Physiologic evaluation of circulatory assistance (cattle)
ROIHL- 13634-08 Renal hypertension in pregnancy (sheep)
ROlHL-13936-06 Microvascular responses in hypertension
(human, rats)
P50HL-14159-08 0021 Specialized center of research in
hypertension ■ Genetic studies of the physiology of
hypertension (human, rats)
P50HL-14187-07 0005 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses - Pulmonary
hypertension and cardiac function (dogs, human)
P50HL-14214-07 0030 Newborn lung center for hyaline
membrane disease ■ Effects of ductal patency-Impedance
cardiography and echocardiography (human)
P50HL-14230-07 0088 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Coronary risk factors in school children-
The Muscatine study
POlHL-1438807 0183 Regulation of the circulation in
pathological states - Vasopressin in cardiovascular
regulation (dogs, rats)
POlHL-14414-07 0008 Environmental influences on
cardiorespiratory and cellular functions - Energetics of
swimming (human)
POlHL-14414-07 0015 Environmental influences on
cardiorespiratory and cellular functions - Control of the
cardiovascular system (dogs)
POlHL-14414-07 0016 Environmental influences on
cardiorespiratory and cellular functions ■ Effects of
pressure on membrane and cellular function (human,
rabbits)
ROlHL-14560-07 Hypertension produced by sympathetic
dysfunction (human, rats)
ROlHL-14645-07 Blood flow measurement by ultrasonic
catheter tip methods (human, dogs)
(contd)
■Excludes routine methodok)gy OR covers only general projects which preclude
**Oiiented significantly to above subject.
indexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
HEA
ROlHL-14967-06 Chemoreceptor function in dynamic
ventilatory control (human, dogs)
POlHL-14985-07 0002 Adaptation to tiypoxia ■ Oxygen
transport in man at high altitude
POlHL-14985-07 0003 Adaptation to hypoxia • Hypoxia
and oxygen transport (human, dogs)
POlHL-14985-07 0005 Adaptation to hypoxia - Control
mechanisms in the pulmonary microcirculation (animals)
POlHL-14985-07 0015 Adaptation to hypoxia ■ Pregnancy
at high altitude (human, animals)
P60HL-15158-07 0025 Comprehensive sickle cell center ■
Cardiovascular evaluation of children with sickle cell
disease (human)
ROlHL-15231-05 Mechanisms of hemodynamic changes
during digestion (dogs)
R01HL-15655-D5 Blood flow and gas exchange in placenta
and lungs (sheep) rabbits)
ROIHL 15681-06 Coronary flow studies of partially
obstructed vessels (dogs)
ROlHL-15983-04 Regional myocardial blood flow (dogs)
R01HL-I6315-05 Analysis of interaction between CNS
vasomotor systems (cats, rats)
** ROlHL-16390-05 Cardiopulmonary control coupling in
exercise (dogs)
ROlHL-16656-06 Lett ventricular function in exercise
(dogs)
ROlHL-16784-03 Lung tissue and water volume (human,
dogs)
P01HL16910-05 0006 Regulation of the peripheral
circulation - Regulation of blood flow distribution (baboons,
dogs)
** ROlHL-17246-03 Oxygen uptake at one minute of exercise
(human)
** P60HL-17269-04 0030 National heart and blood vessel
research and demonstration center - Cardiovascular
engineering laboratories (human)
P60HL-1 7269-04 0032 National heart and blood vessel
research and demonstration center - Clinical circulatory
assist device fabrication
ROlHL-17341-03 Practical total synthesis of
prostaglandins
ROlHL-1 7366-05 Mechanisms in the production of renal
hypertension (rabbits, dogs)
** ROlHL-1 7403-03 Metabolic control of cardiac output
(dogs)
ROlHL-1 7459-03 Myocardial ischemia (dogs)
R01HL1759103 Development of electromagnetic
rheoangiography (human, dogs)
P50HL 17646-04 0001 Study of ischemic heart disease -
Core clinical investigation unit
P50HL-17646-04 0014 Study of ischemic heart disease -
Progression of ischemic injury in conscious dogs (also
rabbits)
P50HL-1 7648-04 0006 Study of ischemic heart disease -
Ventricular performance and myocardial perfusion in
obstructive coronary disease
P50HL-17651-04 0002 Ischemic heart disease specialized
center of research • Reduction of myocardial ishemic injury
by pharmacologic agents (human, dog)
P50HL-17651-04 0023 Ischemic heart disease specialized
center of research - Development of multipurpose catheter
tor monitoring and electronic pacing
P50HL-17651-04 0032 Ischemic heart disease specialized
center of research - Cardiovascular surgery core (human,
dogs)
P50HL- 1765 1-04 0043 Ischemic heart disease specialized
center of research - Gradual reperfusion following acute
coronary occlusion (dog)
P50HL-17651-04 0045 Ischemic heart disease specialized
center of research - Peripheral vascular studies -
Pharmacology (dogs, human)
P50HL-1 7655-04 0003 Study of ischemic heart disease ■
Cardiopulmonary resuscitation (human, dog)
P50HL-1 7655-04 0011 Study of ischemic heart disease -
Core facility-Cardiovascular nuclear medicine (human, dog)
P50HL-1 7665-04 0022 Study of ischemic heart disease -
Effect of coronary revascularization on left ventricular
function (human)
P50HL-1766504 0026 Study of ischemic heart disease -
Anesthesia-Myocardial ischemia and hemodynamics in
coronary disease (human)
P50HL-1 7665-04 0027 Study of ischemic heart disease -
Positron imaging of regional myocardial perfusion (human,
dog)
P50HL-I766704 0018 Study of ischemic heart disease -
Arrhythmias in ischemic heart disease (human)
P50HL-1 7667-04 0022 Study of ischemic heart disease -
Preventing myocardial injury in surgery using
cardiopulmonary bypass (human, rat)
P50HL-1 7667-04 0030 Study of ischemic heart disease -
Computerized clinical data acquisition and processing
P50HL- 17669-04 0013 Ischemic heart disease center
(SCOR) - Exercise in patients with ischemic heart disease
P50HL-1 7670-04 0015 Study of ischemic heart disease -
Radionuclide studies of myocardial ischemia (human)
P50HL-1 7682-04 0007 Study of ischemic heart disease ■
Mechanisms of hypoxemia in myocardial infarction (human)
ROlHL-17808-03 Effect of altered oxygen affinity on
oxygen transport (human, rats)
ROlHL-17958-04 Circulatory effects of operant
cardiovascular control (baboons)
264
ROlHL-17993-04 0003 Ventricular dynamics from
surgically inserted markers - Effects of pharmacologic
agents on left ventricular dynamics (human)
ROlHL-17993-04 0006 Ventricular dynamics from
surgically inserted markers - Atrial pacing in transplant
patients
ROlHL-17993-04 0008 Ventricular dynamics from
surgically inserted markers • Exercise after coronary bypass
(human)
ROlHL-18024-03 Regional myocardial flow and function
relationships (dogs)
P50HL 18318-03 0010 Pathogenesis and complications of
hypertension - Hemodynamics in mineralocorticoid and low
renin hypertension (human)
P50HL-18323-04 0012 SCOR hypertension center - Renin
as a risk factor (human)
P50HL-18323-04 0042 SCOR hypertension center - Blood
viscosity and blood volume in hypertensive disease
(human, dog)
P50HL-18323-04 0046 SCOR hypertension center -
Coronary artery bypass surgery -Associated hypertension
(human)
ROlHL-18560-03 Cardiovascular adaptation to stress
(miniature swine)
POlHL-18575-03 0002 Mechanisms of vascular changes
in hypertension - Endocrines, electrolytes, and
hemodynamics in hypertension (pigs)
POlHL-18575-03 0006 Mechanisms of vascular changes
in hypertension - Evaluation of arterial compliance in
hypertension (human, pigs)
POIHL 18708-03 0009 Oxygen, energy and contractility in
cardiac tissue - Regulation of oxygen utilization of cardiac
tissue (rats, rabbits)
ROlHL-18862-02 Thirst and its contribution to edema
(dogs)
ROlHL-18933-03 Energy output and efficiency of left
ventricle (dog)
POlHL-18974-03 0001 Experimental neurogenic
hypertension program - Central neural systems regulating
arterial pressure (rabbits)
POlHL-18974-03 0006 Experimental neurogenic
hypertension program - Model of sustained arterial
hypertension (cats)
POIHL- 189 74-03 0008
hypertension program
(rats)
ROlHL-18976-03 Blood pressure control-Relation to
behavioral stress (human, dog)
ROlHL-19039-03
model (dogs)
ROlHL-19091-02
(dogs)
Contraceptive steroids and experimental
Experimental neurogenic
Monoamines and hypertension
Circulation studies by one vs two circuit
Sustained increase in cardiac output
ROlHL-19144-03
hypertension (rats)
P50HL-19155-02 0004 Pathophysiology of pulmonary
edema - Physical and chemical effects of multiple
pulmonary emboli (sheep)
P50HL-19 190-02 0008 Pulmonary SCOR-Pathophysiology,
management of IRDS - Hemodynamics and gas exchange-
Determinants of hypotension (human, infant)
P50HL-19190-02 0009 Pulmonary SCOR-Pathophysiology,
management of IRDS - Developing non-invasive neonatal
pulmonary monitoring systems (rabbit, human)
ROlHL-19225-02 0003 Types and mechanims of
pulmonary hypertension - Cardiopulmonary function in pigs
and rats
ROlHL-19256-03 Arterial baroreceptors in cardiovascular
control (dogs)
ROlHL-19287-03 The antihypertensive function of the
renal medulla (human, rats, rabbits)
ROlHL-194 10-03 Dynamic interrelations underlying
exercise hyperpnea (human)
ROlHL-19425-03 Cardiac function in hypertrophy (dog)
ROlHL-19449-03 Gas exchange in acute respiratory failure
R01HL19461-03 Myocardial energetics in hypertrophy and
heart failure (rabbits)
R01HL-19680-01 Cardiac correlates of behavioral stress in
animals (dog)
ROlHL-1987003 Hypertensive progeny-Physical and
humoral precursor search
R01HL-20124-02 Coronary risk factors (human)
R01HL-20187-01 Evaluation of exercise cardiac
rehabilitation program (40-55 year old men)
ROlHL-20356-02 Development and evaluation of an
artificial heart (calves)
ROlHL-203 71-02 Intravascular redistribution of blood
volume (dogs)
ROIHL-204 76-03 Effects of diabetes on cardiac
performance (rat)
ROlHL-20484-03 Effects of diabetes on cardiac function
and metabolism (rats)
ROlHL-20542-03 Regional hemodynamics in spontaneous
hypertension (rats)
POlHL-20552-02 0002 The development and regression of
cardiac hypertrophy - Effect of treatment on the
hypertrophied left ventricle (rats)
POlHL-20552-02 0004 The development and regression of
cardiac hypertrophy - Ventricular function in experimentally
induced hypertrophy (hogs, sheep, baboons)
ROlHL-205 72-02 0001 Hemodynamic relations to
metabolism in hypertension - Hemodynamic and myocardial
functional studies in the SHR (rat)
HEA
ROlHL-20572-02 0003 Hemodynamic relations to
metabolism in hypertension - Cardiac output and organ
blood flow in hypertension (rats)
ROlHL-20572-02 0007 Hemodynamic relations to
metabolism in hypertension - Drug effects on cardiac
function and hypertropy (rats)
' ROlHL-20612-02 Chronic animal model of pulmonary
vascular injury (dogs)
ROlHL-20630-03 Development of a pulsed Doppler velocity
detector (human, animals)
ROlHL-20634-01 Blood volume and venous return in
thermal strain (human)
ROlHL-20690-02 Pulmonary hemodynamics in lung edema
during PEEP (dogs)
ROlHL-20895-03 0001 Cineangiographic studies of
cardiovascular system - Videodensitometry and valvular
regurgitation (human, dogs)
ROlHL-20895-03 0011 Cineangiographic studies of
cardiovascular system - Ventricular hypertrophy and
preoutflow contraction (human, dogs)
POlHL-20994-02 0002 Dynamics of neutrophil elastase in
the lung - Neutrophil and neutrophilic elastase in human
lungs
ROIHL 2107602 Lung fluid, protein exchange after
hemorrhagic shock (sheep)
R23HL-21 168-01 Hypoxemic respiratory failure -Physiologic
evaluation (human, dogs)
R23HL-21 197-02 Right ventricular contraction and
relaxation (dogs)
ROlHL-21245-02 Influence of chronic exercise on
hypertension (rats, primates)
ROlHL-21278-01 Abnormal cardiac wall motion viewed
ultrasonically (human, dogs, phantoms)
ROlHL-21435-02 Control, cardiovascular and renal effects
of potassium (dogs)
R23HL-21462-02
arteries (dogs)
ROlHL-21523-01
in man
ROlHL-21578-01
adolescent
R01HL-21673-01 Pathophysiology of venous changes in
hypertension (rats, rabbits, human, dogs)
ROlHL-21690-02 Sequential multinuclide study of acute
infarction (human, dogs)
ROlHL-21893-01 Blood volume distribution in hypertension
(human)
ROlHL-22321-01 Cardiac output from the
pneumocardiogram (dogs)
Mechanical interactions between ventricle
Hemodynamic effects of dietary sodium
Effect of exercise upon the hypertensive
ROlHL-2232601
output (dogs)
ROlHL-22506-01
hypertensions
ROlHL-22546-02
ROlHL-2254701
disease (human)
ROlHL-22594-01
failure (dogs)
ROlHL-2261701
(sheep)
R23HL-22669-01
afferents (dogs)
ROlHL-22715-01
reflexes (dogs))
ROlHL-2277801
ionophores
ROlHL-22977-01 Role of vasoconstrictor mechanisms in
heart failure (human, dogs)
ROlHL-2298201 Multicenter postcoronary risk
stratification program (human)
R01HL-23015-01 Mechanisms of hypo-oncotic pulmonary
edema (human, dogs)
ROlHL-23201-01
rats)
ROlHL-23211-01
Noninvasive measurement of cardiac
Hemodynamics of ttie clinical
Baroreceptor reflex mechanisms in man
Behavioral treatment of Raynaud's
Reflex control of the circulation In heart
Angiotensin, hypertension and the CNS
Cardiovascular effects from visceral
Neural integration of the cardiovascular
Total synthesis of natural cardiotonic
Mechanisms of hypertension (human.
Active normoxic pulmonary vasodilatation
•Excludes routine methodotogy OR covers only general projects which preclude indexing at the specific level
Oriented significantly to above subject.
M Grant has subproierts describing specific research aspects.
See Appendix for :■■ -alor's name and grant number.
(rat, dog, sheep)
ROlHL-23312-01 Hemodynamics and vasoactivity in renal
hypertension (human, dogs)
ROlHL-23653-01 Protection of the ischemic myocardium
(dogs)
R01HL-23970-01 Mechanisms and control of sudden
cardiac death (human, dog)
NOlHV-12060-18 Tissue cultured endothelium for vascular
prosthetic devices (human, animals)
NOlHV-72937-00 Left heart assist blood pumps (calves)
NOlHV-72975-02 Energy converter for left ventrical assist
devices (calves)
HEART FUNCTION, HEART CONTRACTION
R01HL-01015-27 Hypertension and left ventricular
hypertrophy (dogs)
ROlHL-01755-25 Fetal and neonatal cardiovascular
function (sheep)
** ROlHL-03290-22 Controls of cardiac and vascular smooth
muscles (cats, rats, dogs)
** POlHL-04664-18 0004 Cardiovascular and lung dynamics
- X-ray cross section imaging of the circulation (dogs)
" POlHL-04664-18 0011 Cardiovascular and lung dynamics
- Detection of abnormal segments of the human ventricle
by measure of asynergy
POlHL-04664-18 0013 Cardiovascular and lung dynamics
- Ventricular function in coronary disease using NTG and
ventriculograms (human)
(contd)
HEA
P01H104664 18 0015 Ordiovssculai and lun| dynimics
Computei system lot the catdiov«scul»t laboritory
R01HlOi883 18 0004 Rellex control ol resistance and
capacitance vessels Lett ventricular receptors with
nonmedullated vajal atlerents (cats)
•• PO1HL06285 18 0153 Cardiovascular respiratory
ptiysiology and biochemistry Myocardial mechanics and
pharmacology in isolated papillary muscle (animals)
POIHI 06285 18 0154 Cardiovascular respiratory
physiology and biochemistry Function and viability ol
cnlically ischemic myocardium (dogs)
*• P01HL06285 18 0155 Cardiovascular respiratory
physiology and biochemistry Therapeutic alterations,
contractile state in heart lailure
P01HL06285 18 0156 Cardiovascular respiratory
physiology and biochemistry Myocardial perlormance
lolloviing revascularization (human)
** PO1HL06285 18 0157 Cardiovascular respiratory
physiology and biochemistry Left ventricle outllovi
impedance analysis (human)
*• P01HL06285-18 0158 Cardiovascular-respiratory
physiology and biochemistry Load on myocardial
contractility (dogs)
P01HL0628518 0173 Cardiovascular-respiratory
physiology and biochemistry SKeletal and cardiac muscle
function
P01HL06308-18 0029 Mechanisms and therapy of
circulatory disease Characterization ol the patient with
recurrent ventricular arrhythmias
POIHL 06308 18 0035 Mechanisms and therapy ol
circulatory disease Mechanisms lor electrophysiological
changes in myocardial infarction (dogs)
POlHL-06308-18 0044 Mechanisms and therapy ol
circulatory disease • Echocardiography to determine site ol
ectopic impulse lormation (human, dogs)
POlHL-06312 17 0036 Surgical cardiology - Experimental
studies of cardiac compliance (dogs)
POlHL-06312-17 0044 Surgical cardiology - The limits of
topical cardiac hypothermia with ice chips (rats)
P01HL0631417 0065 Immunologic mechanisms in
cardiovascular disease - Transplantation biology and
clinical transplantation
POlHL-06835-17 0041 Cardiovascular disease - Cardiac
performance in rats with renal hypertension
POlHL-06835-17 0042 Cardiovascular disease -
Myocardial hypertrophy due to renal hypertension (rats)
** P01HL06835-17 0060 Cardiovascular disease -
Ventricular performance experimental models of arterial
hypertension (rats, dogs)
ROlHL-07139-17 Cardiodynamics and metabolism ol
congestive lailure (human, dogs)
M P01HL-07293-17 Non-invasive cardiovascular
measurements
POlHL-07293-17 0041 Non-invasive cardiovascular
measurements • Ventricular volumes and dimensions
(human)
POlHL-07293-17 0043 Non-invasive cardiovascular
measurements - ECHO-Doppler instrumentation for cardiac
measurements (human)
POlHL-07293-17 0053 Non-invasive cardiovascular
measurements ■ Clinical evaluation of cardiac dimensions
using the duplex scanner (human)
** ROlHL-08659-14 Myocardial performance and metabolism
in the newborn (sheep)
M P01HL-0868215 Regulation of the cardiovascular system
P01HL-08682-15 0015 Regulation of the cardiovascular
system - Projection of autonomic nerves onto the heart
(dog)
POlHL-0868215 0017 Regulation of the cardiovascular
system - Neurally induced cardiac dysrhythmias (dog)
** POlHL-08682-15 0031 Regulation of the cardiovascular
system - Cardiac electrophysiology in hibernation (ground
squirrel, marmot)
POlHL-08682-15 0033 Regulation ol the cardiovascular
system - Functional and anatomical relations during
cardiac re-innervation (dog)
POlHL-0868215 0036 Regulation ol the cardiovascular
system - Electrolyte transport in myocardium with
hemorrhagic shock (rats)
POlHL-0880515 0050 Regulation of ventilation and
pulmonary circulation - Right ventricular mechanics (dogs)
•* ROlHL-09234-13 Amino acids of contractile proteins of
failing hearts (dogs, hamsters)
ROlHL-09552-14 Cardiac protein synthesis, overload,
alcohol and anoxia (guinea pigs)
ROlHL-09711-13 Instantaneous blood flow in ascending
aorta (human, dogs)
" R01HL-10018-11 Effect of aging on beating heart cells in
culture (rats)
POlHL-10342-13 0008 The integrated function of
respiration and circulation - Respiratory mechanics and the
circulation (human, dogs)
ROlHL-10503-13 Cardiac ion transport and ultrastructure
(rats, guinea pigs, rabbits)
** POlHL-10539-12 0067 Pathophysiology of circulation -
Mechanical, electrophysiological studies -Isolated heart
muscle (dog, rat)
POlHL-10539-12 0068 Pathophysiology of circulation -
Acute and chronic cardiomyopathies (mice, dogs, hamsters,
human)
265
POIHI 10539 1? 0069 Pathophysiology ol circulation
Ventricular compliance and mechanics in intact ventricles
(human)
ROIHI 10897 12 Ellects ol hormones on cardiac
eleclrogenesis (rabbits, guinea pigs, dogs)
*• ROIHL 10951 11 Neural control ol the heart (dogs, rats)
•* POIHL 11307 12 0003 Biophysical studies m pediatric
cardiology Cellular biophysics (animals)
POIHL 11310 12 0055 Mechanisms ol cardiovascular
disease Ventricular pressure volume alter intracardiac
surgery (human)
*• POIHL 1131012 0059 Mechanisms of cardiovascular
disease Contractility Acute response to diogoxin after
heart surgery (children)
POIHL 11310-12 0061 Mechanisms of cardiovascular
disease Computer simulation of transposition of great
arteries in infants
POIHL 11310 12 0081 Mechanisms ol cardiovascular
disease Analysis ol regional left ventricular function
(human)
*• POIHL 1131012 0085 Mechanisms ol cardiovascular
disease Mechanics ol isolated cardiac muscle (animals)
•* POIHL 11310 12 0086 Mechanisms ol cardiovascular
disease Mechanics of the intact left ventricle (dogs)
** POIHL 1131012 0087 Mechanisms of cardiovascular
disease Electrophysiology and electropharmacology of the
heart (dogs)
•* POlHL-1 13 10-12 0089 Mechanisms of cardiovascular
disease - Structure and function in myocardial contraction
(dogs)
** POlHL-1131012 0094 Mechanisms of cardiovascular
disease Physics of pulsatile fluid flow (dogs)
M POlHL-1 1351-12 Cellular and molecular mechanisms of
myocardial function
" POlHL-11351 12 0001 Cellular and molecular
mechanisms of myocardial function Ionic control of
myocardial contractility (animals)
•* POIHL 1135112 0003 Cellular and molecular
mechanisms of myocardial function - Mechanical and
electrical properties ol cardiac muscle (rabbits)
** POlHL-11351-12 0004 Cellular and molecular
mechanisms of myocardial function • Molecular
mechanisms ol contractile lunction and dillerentiation
(animals)
POlHL-1 1351-12 0005 Cellular and molecular
mechanisms ol myocardial lunction - Electrophysiology ol
cardiac muscle (rats)
** POlHL-1 1351-12 0006 Cellular and molecular
mechanisms ol myocardial lunction ■ Molecular physiology
and energetics ol muscle (frogs)
** POlHL-11351-12 0010 Cellular and molecular
mechanisms of myocardial function - Basic ionic exchange
studies (rats)
POlHL-1 1351-12 0011 Cellular and molecular
mechanisms of myocardial function - Comparative
contractile tissue studies (animals)
** POlHL-11351-12 0013 Cellular and molecular
mechanisms of myocardial function - Ion exchange in the
perfused septum high-resolution technique (rabbits, rats)
POlHL-11351-12 0019 Cellular and molecular
mechanisms of myocardial function - Mechano-chemical
kinetics of small perturbations
POlHL-1141411 0034 Thrombosis and atherosclerosis
program - Servo simulation -Experimental myocardial
infarction (dogs)
ROlHL-11906-11 Comparative study of heart function
(cats, rats, hedgehogs, squirrels)
POlHL-12157-11 0057 Functions and mechanisms of cell
membrane ion transport - Electrophysiological
investigations of synthetic strands of heart muscles (rats)
** P01HL12373-10 0001 Cardiopulmonary physiology and
pathophysiology - Mechanics of myocardial contraction
(dogs, rats, swine)
** POlHL-12373-10 0002 Cardiopulmonary physiology and
pathophysiology - Determinants of performance of the
whole heart (dogs)
** POlHL-12373-10 0003 Cardiopulmonary physiology and
pathophysiology - Myocardial function in man
P01HL12373-10 0005 Cardiopulmonary physiology and
pathophysiology - Characterization of fetal and neonatal
myocardium (human, cats)
POlHL-12373-10 0012 Cardiopulmonary physiology and
pathophysiology - Biochemistry of the sympathetic nervous
system (rats, rabbits, pigeons)
ROlHL-12576-10 Bioenergetics apparatus in heart
mitochondria
R01HL-12711-09 Mathematical approach to cardiovascular
mechanics (human, animals)
POlHL-12738-10 0035 Physiologic pharmacology and its
clinical applications - Function and dysfunction of the
sinoatrial node (human)
POlHL-12738-10 0111 Physiologic pharmacology and its
clinical applications ■ Cardiovascular pharmacology (dogs)
** ROlHL-12774-08 Ionic coupling in activation of cardiac
muscle (frogs, guinea pigs)
** ROlHL-12997-07 Myocardial defects induced by potassium
depletion (human, rats, cats)
ROlHL-13028-09 Regulation of myocardial fatty acid
metabolism (rats)
** POlHL-13108-09 0017 Clinical heart transplantation -
Electrophysiology of the transplanted denervated human
heart
HfA
POIHI 13108 09 0022 Clinical heart tian^planlalion
Studies on cardiac receptors (human)
POIHL 13108 09 0023 Clinical heart ltan^pl8ntallon
Adaptive mechanisms ol the denervated heart (human)
POIHL 13108 09 0024 Clinical heart transplantation
Response ol denervated heart to stress Noninvasive
(human)
ROIHL 1334906 Analysis of activation process in heart
muscle (guinea pigs, rabbits, human)
• POIHL 1348009 0026 Cardiac electrophysiology Neural
influences on cardiac electrophysiology and contraction
(dog. cat)
POIHL 13480 09 0032 Cardiac electrophysiology Cardiac
activation sequence (dogs)
POIHL 1373707 0024 Assisted circulation Dynamic
prosthetic myocardium (dogs)
POIHL 13737 07 0036 Assisted circulation Assessment
ol inlarct size Irom hemodynamic measurements
POIHL 1373707 0038 Assisted circulation
Distinguishing the ischemic ventricle Irom scarred ventricle
by balloon pumping
ROIHL 1387009 Control ol myocardial sarcotubular
calcium stores (dogs)
POlHL-14388-07 0173 Regulation ol the circulation in
pathological states Mechanisms ol cardiac myosin ATPase
POlHL-14388 07 0214 Regulation ol the circulation in
pathological states Oelormation pattern and stress
analysis ol the left ventricle
POlHL-14388-07 0215 Regulation of the circulation in
pathological states Left ventricle model in
pathophysiologic states
POlHL-14388-07 0216 Regulation of the circulation in
pathological states Development and regression of
ventricular hypertrophy (cats, rats)
POlHL-14388-07 0217 Regulation of the circulation in
pathological states Fluid mechanics of aortic flow (dogs,
human)
** ROlHL-14461-08 Cardiac metabolism in heart failure
(rats)
ROlHL-14529-07 Systems analysis of baroreflex (dogs)
ROlHL-14545-06 Mechanics of compensatory ventricular
hypertrophy (dogs)
** ROlHL-14614-07 Voltage control of contraction in heart
(sheep)
ROlHL-14644-05 Optimization diastolic augmentation and
systolic sink (dogs)
R01HL14651-05 Mechanical behavior of left ventricle
(dogs, rats)
** ROIHL 14903-07 A new index of cardiac contractility
(human, dogs, baboons)
POlHL-1498507 0003 Adaptation to hypoxia Hypoxia
and oxygen transport (human, dogs)
ROlHL-15416-06 Cardiovascular control in normal and
disease states (dogs, baboons)
** ROlHL-15522-06 Influence of mannitol on ischemia
cardiac muscle (dogs. cats, rats)
** ROlHL-15692-07 Force and speed in skeletal and cardiac
muscle
ROIHL- 15694-06 Pulmonary factors in circulatory
regulation
** ROlHL-15740-06 In vitro studies on heart cell function
(rats)
ROlHL-15758-06 Catecholamine release in the heart
(dogs)
** ROlHL-15764-05 CAMP dependent protein kinase in
cardiac contraction (dogs)
ROlHL-15799-04 Effect ol anesthetics on myocardial
lunction (cats)
M POlHL-15835-06 Study ol muscles related to heart
disease
*• POlHL-15835-06 0001 Study ol muscles related to heart
disease - Control ol contraction-relaxation ol heart and
muscle (rabbits, chickens)
" POlHL-15835-06 0013 Study ol muscles related to heart
disease - Cardiac bioenergetics (rats)
** POlHL-15835-05 0023 Study ol muscles related to heart
disease - Cellular basis ol the Frank-Starling curve (Irogs.
rats)
ROlHL-15837-06 Renin and cardiac hypertrophy in
hypertension (rats)
ROlHL-15888-05 Comparative stereology ol the
myocardium (birds, mammals)
** ROlHL-15985-06 Metabolic and hormonal control ol
cardiac contraction
** ROlHL-16010-16 Cellular basis ol cardiac contractility
(irogs)
ROlHL-16037-06 Molecular properties ol cardiac
adrenergic receptors
ROlHL-16052-05 Cardiac glycosides -Mechanism ol
inotropic action (dogs)
ROlHL-16076-06 Electrophysiology ol librillation and
defibrillation (human)
P01HL161 17-05 0001 Ion movements and membranes in
cardiovascular control - Developmental studies of
contractile cell junctions (rats, rabbits, clasmobranch)
** P01HL161 17-05 0002 Ion movements and membranes in
cardiovascular control - Fluorescence and excitation-
contraction coupling in heart (frogs)
** POlHL-16117-05 0004 Ion movements and membranes in
cardiovascular control - Optical studies of excitation-
contraction coupling (frogs, snakes)
(conld)
•Excludes routine methodology OR covers only general projects which preclude
"Ohented significantly to above subject.
indexing at the specific level-
M Grant has subprojeds descnbing specific research aspects.
See Appendix tor mvestigators name and grant number
HEA
** POlHL-16117-05 0005 Ion movements and membranes in
cardiovascular control - Properties of isolated cell
membranes (rabbits, cats)
M POlHL-16117-05 0C06 Ion movements and membranes in
cardiovascular control - Neuroreceptors and cellular
excitation (fish)
** ROlHL-16152-06 Electrophysiology of neonatal to adult
tieart (cats, frogs, guinea pigs)
** R01HL16240-05 The cardiac histamine receptor (rabbits,
guinea pigs)
R01HL-16292-05 0002 Surgery and non-obstructive
coronary insufficiency - Effects of hypothermia during
cardiopulmonary bypass (dogs)
** ROlHL-16436-04 Role of calcium and thyroxine in heart
function (rats)
** ROlHL-16507-04 Heart cell interactions and cell junction
biogenesis (mice. rats, rabbits)
R01HL16511-04 Sympathetic afferent activity of cardiac
origin (dogs, monkeys)
** ROlHL-16606-11 Contraction in heart and other striated
muscles (frogs)
M POlHL-16607-05 Calcium ion and control of
cardiovascular function
** POlHL-16607-05 0003 Calcium ion and control of
cardiovascular function ■ Calcium transport in
sarcoplasmic membranes (animals)
** ROlHL-16656 06 Left ventricular function in exercise
(dogs)
** ROlHL-16706-04 Excitation-contraction coupling and heart
failure (dogs, rabbits)
ROlHL-16710-03 li/lyocardial subcellular localization of
calcium (dogs)
P60HL-17269-04 0017 National heart and blood vessel
research and demonstration center - Cell membrane (dogs,
rabbits)
P60HL- 17269-04 0022 National heart and blood vessel
research and demonstration center - Medicinal chemistry
(rabbit, dog, guinea pig)
P60HL-17269-04 0026 National heart and blood vessel
research and demonstration center - Dynamics of ischemic
heart disease (human, dog)
** ROlHL-1 7376-04 Analysis of Z bands in heart by optical
diffraction (mammals)
ROlHL-1 7403-03 Metabolic control of cardiac output
(dogs)
ROlHL-17459-03 Myocardial ischemia (dogs)
** R01HL17592-03 Activation and contraction heat in
enlarged hearts (rabbits)
** R01HL17629-03 Developmental aspects of cardiovascular
function (human, cats, rabbits)
** ROlHL-17631-05 Experimental congestive heart failure and
hypertrophy (cats)
P50HL-1 7646-04 0010 Study of ischemic heart disease -
Compliance in ischemic myocardium-Altered cardiac
performance (human, dogs)
P50HL-1764604 0016 Study of ischemic heart disease •
Humoral factors in ischemic heart rhythm, mechanical
performance (dog, rabbit)
** P50HL17648-04 0021 Study of ischemic heart disease -
Biventricular contractile responses to acute myocardial
infarction (mammals)
P50HL-1 7665-04 0012 Study of ischemic heart disease -
Myocardial ischemia-Cardiovascular performance in the
conscious baboon and dog
P50HL-1766504 0026 Study of ischemic heart disease ■
Anesthesia -Myocardial ischemia and hemodynamics in
coronary disease (human)
** P50HL17669-04 0007 Ischemic heart disease center
(SCOR) - Relationship between myocardial depression and
compliance (dogs, cats)
** P50HL-17669-04 0008 Ischemic heart disease center
(SCOR) - Segmental ventricular dysfunction during stress-
induced ischemia (dog, human)
P50HL- 17669-04 0013 Ischemic heart disease center
(SCOR) - Exercise in patients with ischemic heart disease
P50HL-1 7670-04 0020 Study of ischemic heart disease -
Radionuclide evaluation of coronary artery disease (human,
dog)
P50HL1 7670-04 0022 Study of ischemic heart disease -
Myocardial metabolism in hypoxia and recover (rabbit,
toad, dog)
P50HL-1 7682-04 0005 Study of ischemic heart disease -
Regional myocardial perfusion deficits and segmental
contraction disorders in man
P50HL1 7682-04 0024 Study of ischemic heart disease ■
Phosphorylation of cardiac contractile proteins during
ischemia (rat, guinea pig)
ROlHL-17907-04 Brain regulation of cardiac arrhythmia
(pigs, cats, rats)
ROlHL-17954-03 Narcotics and the circulation (human,
dogs, pigs, monkeys)
** R01HL17969-04 Function and structure of semilunar
valves (dogs)
R01HL17993-04 0003 Ventricular dynamics from
surgically inserted markers - Effects of pharmacologic
agents on left ventricular dynamics (human)
ROlHL-17993-04 0005 Ventricular dynamics from
surgically inserted markers - Cardiac dimensions and
dynamic after mitral, aortic valve surgery (human)
R01HL1799304 0006 Ventricular dynamics from
surgically inserted markers ■ Atrial pacing in transplant
patients
266
R01HL17993-04 0008 Ventricular dynamics from
surgically inserted markers Exercise after coronary bypass
(human)
ROlHL-18024-03 Regional myocardial flow and function
relationships (dogs)
ROlHL-18087-03 Development and regression of cardiac
hypertrophy (rats, rabbits)
R01HL18280-03 Regulation of cardiac contractility and
metabolism (rats)
ROlHL-18338-04 Computer feedback study of cardiac
muscle mechanics (rats)
ROlHL-18398-04 Mechanisms of delayed and asymetric
ventricular conduction (human, dogs)
ROlHL-18460-01 Effects of prolonged hypoperfusion on the
myocardium (rabbits)
ROIHL 18517-03 Intrinsic innervation of the heart (dogs)
R01HL18527-03 Subcellular response of heart to
functional overload (hamsters, rats)
ROlHL-18537-04 Regional blood flow after acute
myocardial injury (dogs)
R01HL18554-03 Taurine metabolism in mammalian heart
(rodents, cattle, swine)
ROlHL-18599-02 Cardiovascular pharmacology of
ionophores (dogs)
R01HL18612-03 Thin filament control of heart contraction
(cattle)
POlHL-18646-03 0008 Studies basic to heart
transplantation - Immunophysiology and early detection of
rejection (dogs)
ROIHL 1867603
POlHL-1870803
cardiac tissue
POlHL-18708-03 0004 Oxygen, energy and contractility in
cardiac tissue - Structural-functional studies on
sarcoplasmic reticulum (rabbits)
POIHLI 8708-03 0005 Oxygen, energy and contractility in
cardiac tissue - Cytosolic calcium homeostasis and
bioenergetics of cardiac tissue (animals)
P01HL18708-03 0007 Oxygen, energy and contractility in
cardiac tissue - Surfaces, energy requirements, and
contractile proteins of cardiac cell in vitro
POlHL-18708-03 0009 Oxygen, energy and contractility in
cardiac tissue - Regulation of oxygen utilization of cardiac
tissue (rats, rabbits)
ROlHL-187 11-03
chicks)
ROlHL-1874903
heart (dogs)
R01HL18824-03
Myocardial sarcomere mechanics (rat)
Oxygen, energy and contractility in
Electrophysiology of heart cells (rats.
Ventricular mechanics in the overloaded
Mechanisms of heart failure in
myopathic hamster
ROlHL-18900-03
cardiac cells
R01HL18912-03
(cats, dogs)
R01HLI8933 03
ventricle (dog)
ROlHL-18943-03
ROlHL-18979-02
Intercellular factors in function of
Mechanics of heart muscle contraction
Energy output and efficiency of left
Contractile activity of single cardiac cells
Mechanisms in local regulation of
coronary flow (rabbits)
ROlHL-19044-03 Effect of drugs on development of
cardiac failure (cats)
ROlHL-1905703 Catecholamines and cyclic AMP in
cardiovascular system (rats, dogs)
ROlHL-19089-03 Diastolic properties of the left ventricle
(human, dogs)
ROlHL-19133-03 Contractile and elastic properties of
cardiac muscle (cats)
ROlHL-191 38-03 Contractile activation of skinned cardiac
cells (mammals)
ROIHL- 191 48-03 Myocardial organelle lipid structure and
function (dog, rat)
ROlHL-19181-02 Regulation of heart cAMP-dependent
protein kinase (rodents)
P50HL-191 90-02 0008 Pulmonary SCOR-Pathophysiology,
management of IRDS - Hemodynamics and gas exchange-
Determinants of hypotension (human, infant)
ROlHL-19218-03 Local regulation of coronary flow by
prostaglandins (rabbits)
ROlHL-19246-03 Regression of cardiac hypertrophy-
Myocardial and renal (human)
ROlHL-19325-03 Phosphodiesterase inhibition and muscle
contraction
ROlHL-19343-03 Behavioral influences on cardiac
contractility (monkeys)
R01HL19378-03 Relation of mitochondrial changes to
cardiac failure (dogs, rats)
R01HL-I9391-03 Dynamic determinants of left ventricular
filling (dogs)
ROlHL-1942303
rats)
ROlHL-19425-03
R01HL19451-03
heart
ROlHL-19451-03 0001 Functional characteristics of the
left heart ■ Ventricular performance using epicardial
radiopaque markers (human)
ROlHL-1945103 0003 Functional characteristics of the
left heart - Left ventricular segmental contraction (human,
dogs)
ROlHL-19460-03 Mechanics of the papillary muscle and
the left ventricle (cats, rabbits)
Catecholamine action on the heart (cats.
Cardiac function in hypertrophy (dog)
Functional characteristics of the left
HEA
ROIHL- 1946 1-03 Myocardial energetics in hypertrophy and
heart failure (rabbits)
ROIHL 19485-03 Calcium uptake by normal and failed
cardiac ATPase (dogs)
ROlHL-19487-03 Cardiac actions of digitalis (dogs, cats)
R23HL-1960101 Cardiac response to chronic metabolic
acidosis (rats)
ROIHL 20153-02 Intracellular pH and myocardial
electropharmacology (dogs, guinea pigs)
ROlHL-20286-02 Interventions to improve cardiac function
in ischemia (dogs)
ROlHL-2036903 The effect of alcohol on the heart (rats)
ROlHL-2040103 Relationship of insulin to catechol
cardiomyopathy (rabbit, pig)
ROlHL-20426-03 Myocardial function in diabetes mellitus
(dog, rat)
R01HL-20484 03 Effects of diabetes on cardiac function
and metabolism (rats)
POlHL-20552-02 The development and regression of
cardiac hypertrophy
The development and regression of
Biochemical events in cardiac
POIHL 20552-02 000!
cardiac hypertrophy •
hypertrophy (rats)
P01HL-20G5202 0003
cardiac hypertrophy
The development and regression of
Muscle mechanics of the
hypertrophied left ventricle (rats)
POlHL-2055202 0004 The development and regression of
cardiac hypertrophy • Ventricular function in experimentally
induced hypertrophy (hogs, sheep, baboons)
POIHL 20592-02 Cell biology of cardiac and skeletal
muscle
' POlHL-2059202 0004 Cell biology of cardiac and
skeletal muscle - Excitation, conduction and contraction-
Modelling in Purkinje fibers
' POlHL-20592-02 0005 Cell biology of cardiac and
skeletal muscle - Quantitative voltage studies
' POIHL 2059202 0010 Cell biology of cardiac and
skeletal muscle - Mitochondrial genesis during myocardial
cell hypertrophy and hyperplasia (rats)
ROlHL-20598-03 The coronary vascular response to
ischemia (dogs, pigs)
R01HL-206I3-02 Mechanical properties of isolated
myocardium
' ROlHL-20643-02 Analysis of heart cell contraction (rats)
ROlHL-20658-01 Myocardial energy transport-Creative
kinase (human, cattle, dog)
ROlHL-20749-01 Developing heart-Biophysical aspects
(sheep)
ROlHL-20793-02 Phospholipids and cardiac receptor
function
ROlHL-20895-03 0011 Cineangiographic studies of
cardiovascular system - Ventricular hypertrophy and
preoutflow contraction (human, dogs)
POlHL-20984-02 0001 Cellular mechanisms in cardiac
hypertrophy - Contractile proteins in cardiac hypertrophy
(rabbits, calves)
POlHL-20984-02 0005 Cellular mechanisms in cardiac
hypertrophy - Neurohumoral receptors in cardiac growth
and compensatory hypertrophy (animals)
ROlHL-2101401 Mechanism of the inotropic action of
cardiac glycosides
ROlHL-21038-01 Electrically induced cardiac EM-
histochemical changes (animals)
ROIHL-2114502 Response of atria to hyperosmolallty-
Mechanisms (rabbits)
R23HL-21167-02 The electrophysiology of cardiac
hypertrophy (rats)
ROlHL-21182-02 Active tension and shortening In cardiac
hypertrophy (rabbits)
R23HL-21 197-02
relaxation (dogs)
R23HL-21234-02
(rabbits)
R23HL-2126202 Sodium-calcium interactions In
mammalian myocardium (rabbits, cats)
ROlHL-21278-01 Abnormal cardiac wall motion viewed
ultrasonically (human, dogs, phantoms)
ROlHL-21312-01 Sarcomere mechanics in disrupted
ventricular muscle (guinea pigs)
R23HL-2132502 Sarcomere kinematics in cardiac
contraction (rats, rabbits)
ROlHL-21329-02 Beta-receptor regulation and cardiac
sites of drug action (cat, guinea pig, rat)
R23HL-21393-01 Cardiac adaptation to aging and stress
(rats)
R23HL 21421-01 Myocardial and vascular contractility and
cyclic nucleotides (cattle, rats)
ROlHL-21425-02 Servo-simulated compliance changes-A
reversible Ml (dogs)
ROlHL-21435-02 Control, cardiovascular and renal effects
of potassium (dogs)
ROlHL-2149302 Contractility in cardiac failure (hamsters)
ROlHL-21570-01 The mechanical basis of myocardial
energetics (cats)
ROlHL-21578-01 Effect of exercise upon the hypertensive
adolescent
ROlHL-21657-01
hypoxia (dogs)
ROlHL-21670-01
Right ventricular contraction and
The regulation of cardiac hypertrophy
Regional non-ischcmic myocardial
Antiarrhythmic studies on 2-substituted
aminoindenes (dogs)
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Onented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
(contd)
HEA
ROIHI 21684 02 000b Ridlonuclide mtatct suing and
theupy evaluation Clinical •valuation ol ladioisotope
imaging methods lot quantil>ing infarct size
R01H12U42 01 Fiequency dependent diug actions In
cardiac muscle (rabbits)
•• R23HI 2178301 Ionic control ol contractility in anoxic
myocardium (rabbits, rats)
•* ROIHI.2178501 Lett ventricular wall motion analysis
*• ROIHL 21812 02 Actions ol drugs and ions on cardiac
membranes (rabbits, guinea pigs)
•* ROIHI 2185001 Calcium transport in the hypertrophied
myocaidium (rats, animals)
R01HL21922 01 Transient currents induced by
strophanthidin in the heart
ROIHL 21969 01 Prevention ot myocardial hypoxia during
bypass (rats. mice, squirrels)
ROIHL 2198b 01 Videoroentgenography in congenital heart
disease
•* R01HL2199301 Hypertensive hypettrophy-Eflects of
cardiac mechanics (rats)
*• ROIHL 22008 01 Lett ventriwulat calcium content and
contractility (rats)
ROIHL 2208001 Phosphorus NMR studies on cardiac
tissue (rats, rabbits)
R01HL22101 02 Hormone-substrate interaction in diabetic
myocyte (dogs, rats)
ROlHL-22136-02 Histamine and cardiac adenyl cyclase
** ROIHL 2213702 Structure function pathology of isolated
heart cells (mice, rats)
ROlHL-2215202 Ventricular dysfunction and cardiac
surgery (dogs)
** ROlHL-2226901 Excitation-contraction coupling in
enlarged hearts (rabbits)
** ROlHL-2232901 Active prosthetic myocardium -Effects on
LV function (dogs)
** ROlHL-22354-01 Alphaadrenergic effects on heart
metabolism (rats)
ROlHL-22566-01 Mesoionic purinones as
phosphodiesterase inhibitors
ROIHL 22568-01 pH effect in heart cells-Influence of
cardiac drugs (tissue culture, rats)
R23HL-22575-01 I^actors modifying cardiac digoxin effects
and content (dogs, cats)
M POlHL-22619-01 Cellular mechanisms of heart failure
** POlHL-22619-01 0001 Cellular mechanisms of heart
failure ■ Cell membrane isolation and reconstitution (dogs,
lambs)
** POlHL-22619-01 0002 Cellular mechanisms of heart
failure - Structure of sodium, potasslum-adenosine
triphosphatase (lambs, dogs)
** POlHL-22619-01 0003 Cellular mechanisms of heart
failure ■ Digitalis induced inotropy in myocardial ischemia
heart failure (animals)
** POlHL-22619-01 0004 Cellular mechanisms of heart
failure - Mechanism of action of Na, KATPasc (sheep,
cattle)
** PClHL-22619-01 0005 Cellular mechanisms of heart
failure - Molecular mechanism of regulation of cardiac
muscle contraction (cattle)
** POlHL-22619-01 0006 Cellular mechanisms of heart
failure - Phosphorylation of contractile proteins in cardiac
muscle contraction (dogs, rabb
** POlHL-22619-01 0007 Cellular mechanisms of heart
failure • Regulation of contractile protein levels in heart
muscle (rats)
** POlHL-22619-01 0008 Cellular mechanisms of heart
failure • Molecular mechanisms and differential contractile
responsiveness in VSM (dogs)
** POlHL-22619-01 0010 Cellular mechanisms of heart
failure - Mitochondria in heart and smooth muscle (rabbits,
rats, dogs)
** ROlHL-22651-01 Control of protein metabolism in heart
muscle
R23HL-22669-01 Cardiovascular effects from visceral
atferents (dogs)
** ROlHL-2268501 Drugs and excitation-contraction coupling
in heart (animals)
ROlHL-22813-01 Palmitylcarnitine inhibition of ion pumps
in ischemia (dogs)
** ROlHL-22828 01 Adenosine and catecholamine interaction
in the heart (rats)
** ROlHL-22917-01 Microvascular pressures in the intact
beating heart (rabbits)
R23HL-22959-01 Heart development in inherited
cardiomyopathy (hamsters)
** ROlHL-23128-01 Cardiac contractility-Ischemia and
hypoxia (rabbits, rats)
R01HL-23161-01 0001 Biology of myocardial ischemia -
Mitochondrial lipid metabolism and cardiac ischemia (rat.
dog)
ROlHL-2316101 0002 Biology of myocardial ischemia -
Palmitylcarnitine inhibition of ion pumps in myocardial
ischemia (dog, sheep)
ROlHL-23587-01 Phosphorylation of myocardial protein
(guinea pigs)
ROlHL-23624-01 Effect of drugs on ischemic cardiac cells
(dogs, guinea pigs, pigs)
ROlHL-23980-01 Effects of digoxin therapy in newborn
and adult sheep
** ROlHL-23990-01 Role of phosphoprotein in cardiac
inotropic responses
267
HEART FUNCTION, HEART MOTION
POIHL 04664 18 0004 Cardiovasculai and lung dynamics
X ray cross section imaging of the circulation (dogs)
•* POIHI 04664 18 0011 Cardiovascular and lung dynamics
Detection of abnormal segments of the human ventricle
by measure ol asynergy
POIHL 04664 18 0012 Cardiovascular and lung dynamics
Quantitative single plane left ventricular angiography
(human)
P01HL04664 18 0013 Cardiovascular and lung dynamics
Ventricular function in coronary disease using MTG and
ventriculograms (human)
** P01HL04664 18 0014 Cardiovascular and lung dynamics
Clinical application of computer analysis ot ventricular
wall motion
P01HL04664 18 0015 Cardiovascular and lung dynamics
Computer system for the cardiovascular laboratory
P01HL06285-18 0157 Cardiovascular-respiratory
physiology and biochemistry Left ventricle outflow
impedance analysis (human)
POIHL 06308 18 0011 Mechanisms and therapy of
circulatory disease Blood flow and electrical dysfunction
in ventricular arrhythmia (human)
POlHL-06308-18 0012 Mechanisms and therapy of
circulatory disease Echocardiographic evaluation of
hemodynamics of arrhythmia (human)
POlHL-06308-18 0029 Mechanisms and therapy of
circulatory disease Characterization of the patient with
recurrent ventricular arrhythmias
POlHL-06308-18 0042 Mechanisms and therapy of
circulatory disease Echocardiographic assessment ol
arrhythmias -Myocardial tissue type (human, dogs)
P01HL06308-18 0043 Mechanisms and therapy of
circulatory disease - Exercise and echocardiographic
examining techniques (human)
POlHL-07293-17 0041 Noninvasive cardiovascular
measurements - Ventricular volumes and dimensions
(human)
P01HL07293-17 0043 Non-invasive cardiovascular
measurements ECHOOoppler instrumentation for cardiac
measurements (human)
POlHL-07293-17 0047 Non-invasive cardiovascular
measurements Cardiac scanner system software
P01HL0729317 0053 Non-invasive cardiovascular
measurements - Clinical evaluation of cardiac dimensions
using the duplex scanner (human)
POlHL-1130712 0003 Biophysical studies in pediatric
cardiology ■ Cellular biophysics (animals)
P01HL-I1310-12 0080 Mechanisms of cardiovascular
disease - Metabolism of the hypertrophied myocardium
(human)
** POlHL-113 10-12 0081 Mechanisms of cardiovascular
disease - Analysis of regional left ventricular function
(human)
POlHL-12373-10 0001 Cardiopulmonary physiology and
pathophysiology - Mechanics of myocardial contraction
(dogs, rats, swine)
POlHL-12373-10 0003 Cardiopulmonary physiology and
pathophysiology - Myocardial function in man
POlHL-13108-09 0023 Clinical heart transplantation -
Adaptive mechanisms of the denervated heart (human)
POlHL-13737-07 0038 Assisted circulation -
Distinguishing the ischemic ventricle from scarred ventricle
by balloon pumping
ROlHL-150 16-07 New concepts in cardiac ultrasound
technology (human)
♦* P60HL-1726904 0026 National heart and blood vessel
research and demonstration center - Dynamics of ischemic
heart disease (human, dog)
P60HL17269-04 0027 National heart and blood vessel
research and demonstration center - Non-invasive
evaluation of cardiac function-lschemic heart disease
(human, dog)
ROIHLI 7532-04 Infarct size -ECG, angle, path, correlation
in dogs
P50HL-17646-04 0010 Study of ischemic heart disease -
Compliance in ischemic myocardium -Altered cardiac
performance (human, dogs)
P50HL-17648 04 0004 Study of ischemic heart disease -
Radionuclide imaging studies (human, pig)
** P50HL-17648-04 0006 Study of ischemic heart disease -
Ventricular performance and myocardial perfusion in
obstructive coronary disease
P50HL-17648-04 0021 Study of ischemic heart disease ■
Biventricular contractile responses to acute myocardial
infarction (mammals)
P50HL-17648-04 0034 Study of ischemic heart disease ■
Data management-Hemodynamic data
P50HL-17651-04 0032 Ischemic heart disease specialized
center of research - Cardiovascular surgery core (human,
dogs)
P50HL-17667-04 0030 Study of ischemic heart disease -
Computerized clinical data acquisition and processing
P50HL-17669-04 0006 Ischemic heart disease center
(SCOR) - Studies of hypoxic, acidotic and ischemic cardiac
muscle (dogs)
P50HL-17669-04 0009 Ischemic heart disease center
(SCOR) • Infarct volume-99Tc stannous pyrophosphate
myocardial scintigrams (dogs, human)
P50HL-17669-04 0023 Ischemic heart disease center
(SCOR) Patients with acute myocardial infarction and
myocardial ischemia (human)
HIA
PbOHl 1/6/0 04 0014 Study ol itchemic h««n diMiM
Real time ultrasound imaging in iichemic heart diMiM
(human, dog)
PbOHl 17670 04 0020 Study ol luhemic heart diuat*
Radionuclide evaluation of coronary artery dittate (human.
dog)
P50HL 17682 04 0003 Study of ischemic heart diitaw
Effects of myocardial revascularization in roan
P50HL 17682 04 0005 Study of ischemic heart diieast
Regional myocardial perfusion deficits and segmental
contraction disorders in man
P50HL 17682 04 0013 Study of ischemic heart diieate
Chronic ischemic heart disease Myocardial function and
metabolism (dogs, swine)
ROlHL-1939103 Dynamic determinants of left ventriculir
filling (dogs)
M ROIHL 19451 03 Functional characteristics of the left
heart
•* ROIHL 19451-03 0003 Functional characteristics of the
left heart Left ventricular segmental contraction (human,
dogs) , ..
R01HL19451 03 0004 Functional characteristics ol the
left heart Quantitative coronary arteriography (human)
ROIHL 20630-03 Development of a pulsed Ooppler velocity
detector (human, animals)
ROlHL-2087202 Multidimensional echo imaging of the
ischemic heart
" ROIHL 2089503 0005 Cineangiographic studies o(
cardiovascular system Computerized axial tomography-
Cardiac wall motion and infarction (dogs)
ROlHL-21182 02 Active tension and shortening in cardiac
hypertrophy (rabbits)
** R23HL 21197-02 Right ventricular contraction and
relaxation (dogs)
R23HL-21253-01 Anatomical models in computer-aided
image analysis
** ROlHL-21278-01 Abnormal cardiac wall motion viewed
ultrasonically (human, dogs, phantoms)
R23HL-21325-02 Sarcomere kinematics in cardiac
contraction (rats, rabbits)
ROlHL-2168402 0001 Radionuclide infarct sizing and
therapy evaluation - Evaluating preservation of ischemic
myocardium by radioisotope methods (dog)
*• ROlHL-21684-02 0004 Radionuclide infarct sizing and
therapy evaluation - Image analysis-Kinetics of infarction,
ventricular function (human, animal)
ROlHL-21684-02 0005 Radionuclide infarct sizing and
therapy evaluation - Clinical evaluation of radioisotope
imaging methods for quantifying infarct size
ROlHL-21690-02 Sequential multinuclide study of acute
infarction (human, dogs)
ROlHL-21710-01 Electrocardiographic methods of
quantifying infarct size (human, dogs)
ROlHL-21785-01 Left ventricular wall motion analysis
ROlHL-2179302 Functional infarct size by gated
radioangiography (human, dogs)
R23HL-22787-01 Cardiac volume by biplane
echocardiography (human)
** ROlHL-2291701 Microvascular pressures in the intact
beating heart (rabbits)
NOlHV-62960-00 Techniques to protect ischemic
myocardium and minimize infant size (human)
HEART FUNCTION, HEART RATE
SEE ALSO CARDIOVASCUUR FUNCTION, VASOMOTION, PULSE
PRESSURE WAVES
SEE ALSO HEART DISORDERS. ARRHYTHMIA. BRADYCARDIA
SEE ALSO HEART DISORDERS. ARRHYTHMIA. TACHYCARDIA
ROlHL-04457-20 Cellular aspects of active transport (fish.
rabbits, anurans, turtles)
P01HL04664-18 0002 Cardiovascular and lung dynamics
X-ray cross section imaging of organs (dogs)
ROlHL-05883-18 0008 Reflex control of resistance and
capacitance vessels - Oxygen consumption of the
chronically denervated dog heart
P01HL06285-18 0156 Cardiovascular-respiratory
physiology and biochemistry • Myocardial performance
following revascularization (human)
POlHL-0628518 0158 Cardiovascular-respiratory
physiology and biochemistry - Load on myocardial
contractility (dogs)
P01HL06285 18 0180 Cardiovascular-respiratory
physiology and biochemistry - Vagal C-fibers and their
influence on visceral and somatic function (animals)
POlHL-06308-18 0029 Mechanisms and therapy of
circulatory disease - Characterization of the patient with
recurrent ventricular arrhythmias
POlHL-06308-18 0035 Mechanisms and therapy of
circulatory disease - Mechanisms for electrophysiological
changes in myocardial infarction (dogs)
ROlHL-07575-15 Analysis of time-coherent cardiovascular
data
POlHL-07896-15 0014 Environmental biomedical research
program - Mechanisms of respiration and circulation
(human, dogs)
POlHL-07896-15 0061 Environmental biomedical research
program - Oxygen cost of breathing during graded exercise
(human)
POlHL-08682-15 0015 Regulation of the cardiovascular
system - Projection of autonomic nerves onto the heart
(dog)
(contd)
•Excludes routine methodology OR covers only general projects which preclude
••Oriented signrticantly to above subject.
indexing at the specific level.
M Grant hassubproiectsdescribmg specific research aspects.
See Appendix for investigator's name and grant number
HEA
268
HEA
POlHL-08682-15 0016 Regulation of the cardiovascular
system - Shifting cardiac pacemakers and AV nodal
activation (dog)
POlHL-08682-15 0017 Regulation of the cardiovascular
system - Neurally induced cardiac dysrhythmias (dog)
ROlHL-09154-14 Central control of distribution of organ
blood flow (monkeys)
ROlHL-09711-13 Instantaneous blood flow in ascending
aorta (human, dogs)
ROlHL-09914-13 The myocardium in diabetes mellitus
(dogs, monkeys)
R01HL10384-13 Blood flow and nucleotide metabolism
(animals)
POlHL-10436-13 0014 A multidisciplinary study of
congenital heart disease ■ Cardiovascular pharmacology
(dog)
P01HL10539-12 0064 Pathophysiology of circulation -
Exercise physiology and pathophysiology (human)
POlHL-10539-12 0070 Pathophysiology of circulation ■
Effects of hypertension on myocardial blood flow after
coronary occlusion (dogs)
R01Htl0834-09 Fetal and neonatal pulmonary circulation
(goats)
ROlHL-1095111 Neural control of the heart (dogs, rats)
POlHL-1 1307-12 0002 Biophysical studies in pediatric
cardiology - Cardiac extracellular electrophysiology (human,
dog. chimpanzee)
POIHLI 1310-12 0059 Mechanisms of cardiovascular
disease ■ Contractility -Acute response to diogoxin after
heart surgery (children)
POlHL-1 13 10-12 0061 Mechanisms of cardiovascular
disease - Computer simulation of transposition of great
arteries in infants
POlHL-11310-12 0086 Mechanisms of cardiovascular
disease • Mechanics of the intact left ventricle (dogs)
POlHL-l 1310-12 0092 Mechanisms of cardiovascular
disease - Exercise electrophysiology (human)
POlHL-l 1678-11 0069 Cardiovascular dynamics and their
control - Nervous control of the cirulation (dogs)
P01HL12373-10 0005 Cardiopulmonary physiology and
pathophysiology - Characterization of fetal and neonatal
myocardium (human, cats)
P01HL12373-10 0013 Cardiopulmonary physiology and
pathophysiology - Effects of cardiovascular drugs on left
ventricular function (dogs)
POlHL-12738-10 0065 Physiologic pharmacology and its
clinical applications - Psychotheropeutic drugs and
cardiovascular system (human, rats)
POlHL-12738-10 0132 Physiologic pharmacology and its
clinical applications - Coronary occlusions and arrhythmias
(dogs)
POlHL-13108-09 0017 Clinical heart transplantation -
Electrophysiology of the transplanted denervated human
heart
POlHL-13108-09 0019 Clinical heart transplantation -
Effect of autonomic nervous system on arrhythmias
(human)
P01HL13108-09 0024 Clinical heart transplantation -
Response of denervated heart to stress-Noninvasive
(human)
Cardiorespiratory control in exercise
The cardiac histamine receptor (rabbits.
Neural control of blood volume (monkeys.
Behavioral stress and cardiomyopathy
Renal hypertension in pregnancy (sheep)
Microvascular responses in hypertension
ROlHL-13233-08
(human)
ROlHL-13427-09
dogs)
ROlHL-13454-08
(monkeys, cats)
ROlHL-13634-08
ROlHL-13936-06
(human, rats)
P50HI.-14164-07 0042 A/S SCOR -Comparative and
experimental atherosclerosis - Comparative cardiology
laboratory (monkeys)
P50HL-14214-07 0029 Newborn lung center for hyaline
membrane disease - The diving reflex -Perinatal asphyxia.
pulmonary ischemia and HMD (sheep)
POlHL-14388-07 0184 Regulation of the circulation In
pathological states - Vestibular reflexes in control of
circulation (human)
P01HL14388-07 0185
pathological states
rabbits, dogs)
POlHL-14388-07 0220
pathological states
circulation in man
P01HL14414-07 0015
cardiorespiratory and cellular functions
cardiovascular system (dogs)
P01HL14414-07 0016 Environmental influences on
cardiorespiratory and cellular functions - Effects of
pressure on membrane and cellular function (human,
rabbits)
POlHL-15194-07 0023 Pathophysiology of
cardiopulmonary dysfunction - Distribution of ventilation-
Diffusion and cardiogenic agitation (dogs)
ROlHL-15444-06 Neonatal development of adrenergic
receptor mechanisms (pigs)
ROlHL-15758-06 Catecholamine release in the heart
(dogs)
ROlHL-15888-05 Comparative stereology of the
myocardium (birds, mammals)
ROIHL- 15983-04 Regional myocardial blood flow (dogs)
Regulation of the circulation in
Reflex control of venous tone (human.
Regulation of the circulation in
Pharmacology of the coronary
Environmental influences on
Control of the
ROlHL-16240-05
guinea pigs)
ROlHL-165 11-04 Sympathetic afferent activity of cardiac
origin (dogs, monkeys)
ROlHL-16760-05 Dynamic control of coronaiy blood flow
(dogs)
POIHL- 169 10-05 0007 Regulation of the peripheral
circulation - CNS-Behavloral influences on circulation
(baboons)
P60HL-I7269-04 0026 National heart and blood vessel
research and demonstration center ■ Dynamics of ischemic
heart disease (human, dog)
ROlHL-17341-03 Practical total synthesis of
prostaglandins
ROlHL-17578-04 Exercise performance in children with
heart disease
P50HL-17648-04 0018 Study of ischemic heart disease ■
Myocardial damage-Infarction vectors recalled by
premature atrial stimulation
P50ttL-17651-04 0032 Ischemic heart disease specialized
center of research - Cardiovascular surgery core (human,
dogs)
P50HL-1 7667-04 0018 Study of ischemic heart disease -
Arrhythmias in ischemic heart disease (human)
ROlHL-17954-03 Narcotics and the circulation (human,
dogs, pigs, monkeys)
ROIHL- 179 58-04 Circulatory effects of operant
cardiovascular control (baboons)
ROlHL-17993-04 0006 Ventricular dynamics from
surgically inserted markers - Atrial pacing in transplant
patients
ROlHL-1 7993-04 0008 Ventricular dynamics from
surgically inserted markers - Exercise after coronary bypass
(human)
ROlHL-18024-03 Regional myocardial flow and function
relationships (dogs)
ROlHL-18050-04 Mechanisms of cardiovascular
teratogenesis (chick embryo) k embryo)
ROlHL-18235-03 Cardiovascular fitness and other risk
factors (human)
ROlHL-18454-03 Maximal exercise testing in
hyperlipidemic children
POlHL-18974-03 0001 Experimental neurogenic
hypertension program - Central neural systems regulating
arterial pressure (rabbits)
POlHL-18974-03 0006 Experimental neurogenic
hypertension program - Model of sustained arterial
hypertension (cats)
POlHL-18974-03 0008 Experimental neurogenic
hypertension program - Monoamines and hypertension
(rats)
ROIHL 19076-03 Vagal control of heart rate-A biophysical
model (rabbits)
ROlHL-19256-03
control (dogs)
ROlHL-19378-03 Relation of mitochondrial changes to
cardiac failure (dogs, rats)
ROlHL-19391-03 Dynamic determinants of left ventricular
filling (dogs)
ROIHL- 193 98-03 Regional conduction abnormalities and
arrhythmias (dogs)
ROlHL-19425-03 Cardiac function in hypertrophy (dog)
ROlHL-19451-03 0001 Functional characteristics of the
left heart - Ventricular performance using epicardial
radiopaque markers (human)
ROlHL-19680-01 Cardiac correlates of behavioral stress in
animals (dog)
POlHL-19717-02 0008 Response of the lung to injury -
Experimental models of lung disease
ROlHL-19858-03 UMMC -Blood pressure precursors and
consequences (human)
ROlHL-19864-03 0003 Blood pressure of children and
young adults - Heart rate and blood pressure-Consistency
in infancy (human)
ROlHL-20347-02 Bolus-response measurement of lung
function (human)
ROlHL-20476-03 Effects of diabetes on cardiac
performance (rat)
ROlHL-20484-03 Effects of diabetes on cardiac function
and metabolism (rats)
ROlHL-205 72-02 0001 Hemodynamic relations to
metabolism in hypertension - Hemodynamic and myocardial
functional studies in the SHR (rat)
ROlHL-20598-03 The coronary vascular response to
ischemia (dogs, pigs)
An optimal fetal heart monitor (human)
Control of circulation in heat stress
Cardiac function and metabolism in
Arterial baroreceptors in cardiovascular
Phospholipids and cardiac receptor
ROlHL-20632-02
ROlHL-20766-02
(baboons)
ROlHL-20793-02
function
ROlHL-20864-01 Postnatal maturation of cardiovascular
regulatory system (minipig)
R23HL-21051-02 Adrenergic receptors and the adenylate
cyclase system (frog RBC)
ROlHL-21 145-02 Response of atria to hyperosmolality-
Mechanisms (rabbits)
R23HL-21197-02 Right ventricular contraction and
relaxation (dogs)
ROlHL-21426-02 Learned heart rate control (human)
ROlHL-21451-01 Control of circulation during heat stress
and fever (baboon)
ROlHL-21482-01
diabetes (rats)
ROlHL-2 1532-02 Cardiovascular homeostasis and learning
(frogs, rats, human)
ROlHL-21578-01
adolescent
ROlHL-21672-01
Effect of exercise upon the hypertensive
Antiarrhythmic drug action on VMAZ of
Myocardial perfusion in the hypertrophied
Blood volume distribution in hypertension
cardiac cells
ROlHL-21872-01
heart (dogs)
ROlHL-2 1893-01
(human)
R23HL-21914-01
R23HL-21973-01
(human, guinea pigs)
ROIHL-22032-01
(human)
ROIHL 22154-01
(dog)
ROlHL-22201-01 Pharmacology and chemistry of
nudibranch toxins (guinea pigs, rats, mice)
ROlHL-22239-01 The molecular basis of electrical
excitability (chick embryos, rats)
Studies of vasomotor control (rats)
Catecholamine metabolism and the heart
Cardiovascular events in hypertensives
Cardiac adaptation to physical training
R23HL 22245-02
receptors (rats)
ROlHL-22296-01
ROlHL-22418-01
function (cats)
ROlHL-22426-01 Iritiation of the heartbeat -A voltage-
clamp study (bullfrogs, rabbits)
ROlHL-22512-01 Ultrasonic instrumentation for
cardiovascular studies
ROlHL-22594-01
failure (dogs)
R23HL-22669-01
afferents (dogs)
R23HL-22959-01
Functional characteristics of atrial
Autonomic mechanisms in man
Neural control of cardio-respiratory
Reflex control of the circulation in heart
Cardiovascular effects from visceral
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Oriented signHicanthf to above subject.
M Grant has subprojeds describing specific research aspects.
See Appendix for Investigator's name and grant number.
Heart development in Inherited
cardiomyopathy (hamsters)
ROlHL-2297701 Role of vasoconstrictor mechanisms in
heart failure (human, dogs)
HEART FUNCTION, HEART RHYTHM
SEE ALSO HEART DISORDERS, ARRHYTHMIA
ROlHL-04666-19 Artificially paced hearts-Technology,
physiology (human, dogs)
ROIHL-07139-17 Cardiodynamics and metabolism of
congestive failure (human, dogs)
*" ROlHL-08508-15 Cardiac conductivity and automaticity
(human, dogs, rabbits)
POlHL-08682-15 0017 Regulation of the cardiovascular
system - Neurally induced cardiac dysrhythmias (dog)
** ROlHL-09283-14 Pharmacology of molluscan hearts (also
rabbits)
POlHL-11310-12 0059 Mechanisms of cardiovascular
disease - Contractility -Acute response to diogoxin after
heart surgery (children)
POlHL-11310-12 0079 Mechanisms of cardiovascular
disease - Electrophysiological studies of complete heart
block (human)
POlHL-11310-12 0087 Mechanisms of cardiovascular
disease - Electrophysiology and electropharmacology of the
heart (dogs)
POlHL-11310-12 0092 Mechanisms of cardiovascular
disease - Exercise electrophysiology (human)
POlHL-12373-10 0003 Cardiopulmonary physiology and
pathophysiology - Myocardial function in man
ROlHL-12486-10 Structure-function correlation in the
atrium (rabbits)
POlHL-12738-10 0108 Physiologic pharmacology and Its
clinical applications - Developmental electrophysiology and
pharmacology (human, animals)
POlHL-12738-10 0110 Physiologic pharmacology and its
clinical applications - Physiology and pharmacology of
arrhythmias (dogs)
POlHL-12738-10 0132
clinical applications
(dogs)
ROlHL-13187-09 Central neural control of cardiovascular
function (cats)
POlHL-13480-09 0026 Cardiac electrophysiology - Neural
influences on cardiac electrophysiology and contraction
(dog, cat)
** ROlHL-13666-06 Pharmacology of genesis of cardiac
rhythm icity (rats, cats)
** ROlHL-14832-06 Myocardial cells-Autonomic and rhythmic
mechanisms (chick embryo, rats)
ROlHL-15190-07 Physiological basis of arrhythmias and
their therapy (human)
** ROlHL-16135-05 Mechanisms of cardiac autorhythmicity
(dogs, bats)
ROlHL-17452-04 Depolarization induced cardiac
automaticity (human, animals)
** P50HL-17646-04 0016 Study of ischemic heart disease -
Humoral factors in ischemic heart rhythm, mechanical
performance (dog, rabbit)
** P50HL-17648-04 0018 Study of ischemic heart disease -
Myocardial damage -Infarction vectors recalled by
premature atrial stimulation
P50HL-17667-04 0018 Study of ischemic heart disease -
Arrhythmias in ischemic heart disease (human)
P50HL-17667-04 0029 Study of ischemic heart disease -
Computer diagnosis of cardiac arrhythmias after open
heart surgery (human)
(contd)
Physiologic pharmacology and its
Coronary occlusions and arrhythmias
HEA
•• P50HIU66704 0031 Study ol (schsmic Imrt diseise
PBthophysiology in ischemic heart disease (dot, cat. labbit.
monKey)
•* ROIHL 1904b 03 tlectrophysiolosy ot caidiac automaticity
(human, dogs)
ROIHL 19782 02 Phatmacologic studies on the ischemic
heart (dogs)
•* ROIHL 227M 01 Digoxin m heart lailuie with sinus
rhythm (human)
•* ROIHL 23599 01 Mechanisms ot ischemic ihythm
disorders (dogs)
HEART FUNCTION, HEART SOUNDS
ROIHL 1277709 Mechanisms in cardiac perlormance
(dogs, human)
HEART FUNCTION, INTRACARDIAC PRESSURE
ROIHL 01015 27 Hypertension and letl ventricular
hypertrophy (dogs)
R01HL02493-22 Kidney function in experimental heart
failure (dogs, rats)
POIHL 04664 18 0003 Cardiovascular and lung dynamics
X ray proiection image videometry (human, dogs)
P01HL0466418 0009 Cardiovascular and lung dynamics
Biological signal and image processing techniques (dogs)
POIHL 04664 18 0013 Cardiovascular and lung dynamics
- Ventricular function in coronary disease using NTG and
ventriculograms (human)
POlHL-06285-18 0155 Cardiovascular-respiratory
physiology and biochemistry Therapeutic alterations,
contractile state in heart failure
POlHL-0628518 0157 Cardiovascular-respiratory
physiology and biochemistry - Left ventricle outflow
impedance analysis (human)
P01HL06285-18 0158 Cardiovascular-respiratory
physiology and biochemistry ■ Load on myocardial
contractility (dogs)
POlHL-0630818 0011 Mechanisms and therapy of
circulatory disease Blood flow and electrical dysfunction
in ventricular arrhythmia (human)
P01HL0630818 0012 Mechanisms and therapy of
circulatory disease - Echocardiographic evaluation of
hemodynamics of arrhythmia (human)
** P01HL0631217 0041 Surgical cardiology - A
servomechanism for left ventricular assist (human, dogs,
sheep)
P01HL06664-17 0034 Cardiopulmonary function in
remediable vascular disease - Role of hyperosmolar agents
in ischemic heart disease (dogs)
POlHL-0683517 0041 Cardiovascular disease • Cardiac
performance in rats with renal hypertension
P01HL06835-17 0042 Cardiovascular disease -
Myocardial hypertrophy due to renal hypertension (rats)
** POlHL-06835-17 0043 Cardiovascular disease ■ Left
atrial receptor activity by the sympathetic nervous system
(dogs)
♦* P01HL0683517 0052 Cardiovascular disease - Aortic
distensibility (human)
POlHL-08682-15 0027 Regulation of the cardiovascular
system - Cardiac mechanoreceptors-Reflex regulation of
renal function (dogs)
POlHL-10342-13 0008 The integrated function of
respiration and circulation - Respiratory mechanics and the
circulation (human, dogs)
POlHL-10436-13 0002 A multidisciplinary study of
congenital heart disease - Myocardial performance,
metabolism and ultrastructure (human, cats, rats)
POlHL-10539-12 0069 Pathophysiology of circulation ■
Ventricular compliance and mechanics in intact ventricles
(human)
** POlHL-11310-12 0053 Mechanisms of cardiovascular
disease • Ventricular pressure-volume after cardipulmonary
bypass (dogs)
** POlHL-1 1310-12 0054 Mechanisms of cardiovascular
disease - Mathematical model of ventricular pressure-
volume (human, dogs)
** POlHL-1 1310-12 0055 Mechanisms of cardiovascular
disease - Ventricular pressure-volume after intracardiac
surgery (human)
** POlHL-1 1310-12 0057 Mechanisms of cardiovascular
disease - Blood pressure reduction after heart surgery in
adults (human)
POlHL-11310-12 0058 Mechanisms of cardiovascular
disease - Dynamic response to vasodilating agents
postoperatively (human)
POlHL-11310-12 0060 Mechanisms of cardiovascular
disease - Effect of left atrium on the circulation -Simulation
POlHL-11310-12 0061 Mechanisms of cardiovascular
disease - Computer simulation of transposition of great
arteries in infants
POlHL-11310-12 0064 Mechanisms of cardiovascular
disease - Extracardiac anatomical correction of
transposition of great arteries (puppies)
POlHL-11310-12 0076 Mechanisms of cardiovascular
disease - Tratment of depressed cardiac output following
heart surgery (children, puppies)
POlHL-11310-12 0080 Mechanisms of cardiovascular
disease - Metabolism of the hypertrophied myocardium
(human)
POlHL-1 1310-12 0082 Mechanisms of cardiovascular
disease - Myocardial function in adult congenital heart
disease (human)
269
POIHL 11310 1? 0084 Mechanisms of cardiovascular
disease Evaluation of cardiac function in chronic renal
failure (human)
POIHL 11310 1? 0085 Mechanisms of cardiovascular
disease Mechanics of the intact left ventricle (dogs)
POIHL 11414 II 0034 Thrombosis and atherosclerosis
program Servo simulation Experimental myocardial
infarction (dogs)
POIHL 11678 11 0020 Cardiovascular dynamics and their
control Circulatory and pulmonary fluid dynamics during
pulmonary edema
ROIHL 11876 11 Regional myocardial blood flow and
metabolism (dogs, swine)
POIHL 12373 10 0002 Cardiopulmonary physiology and
pathophysiology Determinants of performance of the
whole heart (dogs)
POIHL 12373 10 0003 Cardiopulmonary physiology and
pathophysiology Myocardial function in man
* ROIHL 12415 10 Evaluation of left ventricular function
(dogs, rabbits)
ROlHL-12711 09 Mathematical approach to cardiovascular
mechanics (human, animals)
POIHL 12738 10 0130 Physiologic pharmacology and its
clinical applications Compatibility enhancement during
cardiac allografting (dogs)
* POIHL 13108-09 0022 Clinical heart transplantation -
Studies on cardiac receptors (human)
POIHL 13108 09 0023 Clinical heart transplantation -
Adaptive mechanisms of the denervated heart (human)
POlHL-13330-08 0034 Mechanical circulatory support In
vivo test and evaluation of left ventricular bypass pumps
(human, cattle)
POlHL-13330-08 0059 Mechanical circulatory support
Physiologic evaluation of circulatory assistance (cattle)
POlHL-13737-07 0009 Assisted circulation Analytical
models
POIHL 1373707 0036 Assisted circulation Assessment
of infarct size from hemodynamic measurements
P50HL-14187-07 0005 Pulmonary SCOR -Chemical
mediators in pulmonary vascular responses - Pulmonary
hypertension and cardiac function (dogs, human)
ROlHL-14529-07 Systems analysis of baroreflex (dogs)
ROlHL-14545-06 Mechanics of compensatory ventricular
hypertrophy (dogs)
R01HL1454405 Optimization diastolic augmentation and
systolic sink (dogs)
ROlHL-147 17-06 Hemodynamics and heart structure-
Ventricular overload (dogs)
** ROlHL-1490307 A new index of cardiac contractility
(human, dogs, baboons)
POlHL-14985-07 0003 Adaptation to hypoxia - Hypoxia
and oxygen transport (human, dogs)
•* POlHL-15194-07 0019 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation, bypass
grafts and diastolic driving pressure (human, dogs)
ROlHL-15444-06 Neonatal development of adrenergic
receptor mechanisms (pigs)
ROlHL-15694-06 Pulmonary factors in circulatory
regulation
R01HL15983-04 Regional myocardial blood flow (dogs)
ROlHL-15292-05 0002 Surgery and nonobstructive
coronary insufficiency Effects of hypothermia during
cardiopulmonary bypass (dogs)
** ROlHL-16292-05 0017 Surgery and non-obstructive
coronary insufficiency • Cardiopulmonary resuscitation
(human)
ROlHL-165 11-04 Sympathetic afferent activity of cardiac
origin (dogs, monkeys)
** ROlHL-16656-06 Left ventricular function in exercise
(dogs)
ROlHL-17459-03 Myocardial ischemia (dogs)
** P50HL-1 7646-04 0010 Study of ischemic heart disease -
Compliance in ischemic myocardium-Altered cardiac
performance (human, dogs)
P50HL17646-04 0013 Study of ischemic heart disease -
Maintenance of myocardial vascular integrity after
revascularization (dogs)
P50HL17648-04 0006 Study of ischemic heart disease -
Ventricular performance and myocardial perfusion in
obstructive coronary disease
P50HL-17651-04 0023 Ischemic heart disease specialized
center of research - Development of multipurpose catheter
for monitoring and electronic pacing
P50HL-17655-04 0003 Study of ischemic heart disease -
Cardiopulmonary resuscitation (human, dog)
P50HL-1766904 0008 Ischemic heart disease center
(SCOR) - Segmental ventricular dysfunction during stress-
induced ischemia (dog, human)
P50HL- 176 70-04 0009 Study of ischemic heart disease -
Surgical treatment of localized left ventricular dyssynergy
(human, dogs)
P50HL-17682-04 0014 Study of ischemic heart disease -
Myocardial ischemia-Instrumentation and technique (dogs,
baboons)
P50HL-17682-04 0015 Study of ischemic heart disease -
Acute myocardial ischemia and infarction and their
reversibility (dogs, baboons)
ROlHL-18024-03 Regional myocardial flow and function
relationships (dogs)
ROlHL-18084-03 Artificial heart and related problems
(calves)
Mc(.hanic% ol heart muulc contraction
Circulation studies by one v. two circuit
Diastolic properties of the left ventricle
Heterogeneity of regional myocardial
Types and mechanims of
Cardiopulmonary function in pigs
Cardiac function in hypertrophy (dog)
Functional characteristics of the left
HIA
POIHl 185/5 03 0006 Meihiinisms of vaicular chjngei
in hypertension Evaluation ol arterial compliance in
hypertension (human, pigs)
ROIHL 18/49 03 Ventricular mechanics in the overloaded
heart (dogs)
ROIHL 18912 03
(cats, dogs)
ROIHL 19039 03
model (dogs)
' ROIHL 19089 03
(human, dogs)
ROIHL 1913504
blood flow (dogs)
ROIHL 1922502 0003
pulmonary hypertension
and rats
ROIHL 1924603 Regression of cardiac hypertrophy
Myocardial and renal (human)
ROIHI 1925703 Cardiovascular adiustmeni to behavioral
stress (dog)
ROIHL 1942503
R01HL1945103
heart
ROIHL 19451 03 0001 Functional characteristics of the
left heart • Ventricular performance using epicardial
radiopaque markers (human)
ROIHL 1946003 Mechanics of the papillary muscle and
the left ventricle (cats, rabbits)
ROlHL-20371 02 Intravascular redistribution of blood
volume (dogs)
ROIHL 20484 03 Effects of diabetes on cardiac function
and metabolism (rats)
POIHL 20552 02 0002 The development and regression of
cardiac hypertrophy - Effect of treatment on the
hypertrophied left ventricle (rats)
POIHL 20552 02 0003 The development and regression of
cardiac hypertrophy • Muscle mechanics of the
hypertrophied left ventricle (rats)
POIHL 20552-02 0004 The development and regression of
cardiac hypertrophy - Ventricular function in experimentally
induced hypertrophy (hogs, sheep, baboons)
ROlHL-20572-02 0001 Hemodynamic relations to
metabolism in hypertension - Hemodynamic and myocardial
functional studies in the SHR (rat)
ROlHL-20612-02 Chronic animal model of pulmonary
vascular injury (dogs)
ROlHL-20630-03 Development of a pulsed Doppler velocity
detector (human, animals)
ROlHL-20690-02 Pulmonary hemodynamics in lung edema
during PEEP (dogs)
R23HL-21 197-02
relaxation (dogs)
R23HL-21393-01
Right ventricular contraction and
Cardiac adaptation to aging and stress
(rats)
ROlHL-21425-02
Servo-simulated compliance changes -A
reversible Ml (dogs)
ROlHL-21452-02 Pulmonary capillary filtration in
myocardial ishemia (dogs)
R23HL-21462-02
arteries (dogs)
ROlHL-21482-01
Mechanical interactions between ventricle
Cardiac function and metabolism in
diabetes (rats)
R23HL-21842-01
Control of sugar entry in normal and
diabetic heart (rats)
ROlHL-21872-01 Myocardial perfusion in the hypertrophied
heart (dogs)
ROlHL-2189301
(human)
ROlHL-22080-01
Blood volume distribution in hypertension
Phosphorus NMR studies on cardiac
tissue (rats, rabbits)
ROlHL-22329-01 Active prosthetic myocardium-Effects on
LV function (dogs)
ROlHL-22594-01 Reflex control of the circulation in heart
failure (dogs)
** ROlHL-22917-01 Microvascular pressures in the intact
beating heart (rabbits)
R23HL-22933-01 Transvascular fluid and protein exchange
in the lung (sheep)
ROlHL-22977-01 Role of vasoconstrictor mechanisms in
heart failure (human, dogs)
ROlHL-23171-01 Coronary collateral circulation in
myocardial ischemia (dog. pig, rat, human)
ROlHL-23224-01
muscle (rat, cat)
ROlHL-23653-01
(dogs)
NOlHV-72975-02
devices (calves)
HEART FUNCTION, INTRACARDIAC VOLUME
POlHL-04664-18 0001 Cardiovascular and lung dynamics
- X-ray projection image videodensitometry (dogs)
POlHL-04664-18 0002 Cardiovascular and lung dynamics
- X-ray cross section imaging of organs (dogs)
POlHL-04664-18 0003 Cardiovascular and lung dynamics
- X-ray proiection image videometry (human, dogs)
POlHL-04664-18 0009 Cardiovascular and lung dynamics
- Biological signal and image processing techniques (dogs)
ROlHL-06143-18 Response of the totally denervated heart
to exercise (dogs)
POlHL-06285-18 0155 Cardiovascular-respiratory
physiology and biochemistry - Therapeutic alterations,
contractile state in heart failure
(contd)
Hypoxia and pulmonary vascular smooth
Protection of the ischemic myocardium
Energy converter for left ventrical assist
•Excludes routine methodology OR covers only general projects which preclude
"Oriented significantly to above subject.
indexing at the specific level.
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigators name and grant number.
HEA
POlHL-06285-18 0157 Cardiovascular-respiratory
physiology and biochemistry - l.eft ventricle outflow
impedance analysis (human)
POlHL-06285-18 0158 Cardiovascular-respiratory
physiology and biochemistry - Load on myocardial
contractility (dogs)
POlHL-06296-18 0003 Cardiovascular and pulmonary
adaptation to stress - Human exercise studies (human,
dogs)
POlHL-0630818 0012 Mechanisms and therapy of
circulatory disease - Echocardiographic evaluation of
hemodynamics of arrhythmia (human)
POlHL-06664-17 0034 Cardiopulmonary function in
remediable vascular disease - Role of hyperosmolar agents
in ischemic heart disease (dogs)
** POlHL-07293-17 0041 Non-Invasive cardiovascular
measurements ■ Ventricular volumes and dimensions
(human)
** POlHl.07293-17 0042 Non-invasive cardiovascular
measurements - Ventricular imaging softviare (human)
POlHL-0729317 0045 Non-invasive cardiovascular
measurements - Cardiac scanner transducer position
locating systems (human)
POlHL-07293-17 0047 Non-invasive cardiovascular
measurements - Cardiac scanner system software
P01HL07293-17 0050 Non-invasive cardiovascular
measurements - Cardiac dimensions measurements
engineering evaluation and error analysis
POlHL-0729317 0051 Non-invasive cardiovascular
measurements - Physiologic evaluation of duplex scanner
(dogs)
POlHL-07293-17 0053 Non-invasive cardiovascular
measurements - Clinical evaluation of cardiac dimensions
using the duplex scanner (human)
POlHL-07293-17 0059 Non-invasive cardiovascular
measurements - Intracardiac blood flow measurement
(human)
•* ROlHL-10330-11 Physiological mechanics of the heart and
arteries (dogs, rabbits, horses)
POlHL-10342-13 0008 The integrated function of
respiration and circulation - Respiratory mechanics and the
circulation (human, dogs)
POlHL-10436-13 0002 A multidisciplinaiy study of
congenital heart disease - Myocardial performance,
metabolism and ultrastructure (human, cats, rats)
POlHL-1043613 0006 A multidisciplinary study of
congenital heart disease - Ventricular blood pumps and
valves (human, cattle)
P01HL10539-12 0069 Pathophysiology of circulation -
Ventricular compliance and mechanics in intact ventricles
(human)
** POlHL-11310-12 0053 Mechanisms of cardiovascular
disease - Ventricular pressure-volume after cardipulmonary
bypass (dogs)
** POlHL-1131012 0054 Mechanisms of cardiovascular
disease - Mathematical model of ventricular pressure-
volume (human, dogs)
** P01HL11310-12 0055 Mechanisms of cardiovascular
disease ■ Ventricular pressure-volume after intracardiac
surgery (human)
P01HL11310-12 0061 Mechanisms of cardiovascular
disease - Computer simulation of transposition of great
arteries in infants
POIHLI 1310-12 0064 Mechanisms of cardiovascular
disease - Extracardiac anatomical correction of
transposition of great arteries (puppies)
P01HL-1131D-12 0081 Mechanisms of cardiovascular
disease ■ Analysis of regional Ijft ventricular function
(human)
POlHL-1 1310-12 0082 Mechanisms of cardiovascular
disease - Myocardial function in adult congenital heart
disease (human)
** P01HL-n310-12 0083 Mechanisms of cardiovascular
disease - Ventricular volume and hemodynamics in adult
congenital heart disease
POlHL-1131012 0084 Mechanisms of cardiovascular
disease - Evaluation of cardiac function in chronic renal
failure (human)
POlHL-l 1310-12 0086 Mechanisms of cardiovascular
disease • Mechanics of the intact left ventricle (dogs)
POlHL-12373-10 0001 Cardiopulmonary physiology and
pathophysiology - Mechanics of myocardial contraction
(dogs, rats, swine)
POlHL-12373-10 0002 Cardiopulmonary physiology and
pathophysiology - Determinants of performance of the
whole heart (dogs)
P01HL1237310 0003 Cardiopulmonary physiology and
pathophysiology - Myocardial function in man
P01HL12373-10 0005 Cardiopulmonary physiology and
pathophysiology • Characterization of fetal and neonatal
myocardium (human, cats)
POlHL-12373-10 0013 Cardiopulmonary physiology and
pathophysiology - Effects of cardiovascular drugs on left
ventricular function (dogs)
** POlHL-12373-10 0019 Cardiopulmonary physiology and
pathophysiology - Free ranging animal facility
** ROlHL-12415-10 Evaluation of left ventricular function
(dogs, rabbits)
ROlHL-12711-09 Mathematical approach to cardiovascular
mechanics (human, animals)
270
POlHL-12738-10 0130 Physiologic pharmacology and its
clinical applications - Compatibility enhancement during
cardiac allografting (dogs)
POlHL-13 108-09 0022 Clinical heart transplantation ■
Studies on cardiac receptors (human)
POlHL-13108-09 0023 Clinical heart transplantation -
Adaptive mechanisms of the denervated heart (human)
P01HL13330-08 0059 Mechanical circulatory support ■
Physiologic evaluation of circulatory assistance (cattle)
ROlHL-13623-08 Atrial receptors (dogs)
P01HL13737-07 0009 Assisted circulation - Analytical
models
P50HL 14187-07 0005 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses - Pulmonary
hypertension and cardiac function (dogs, human)
ROlHL-14529-07 Systems analysis of baroreflex (dogs)
ROlHL-14545-06 Mechanics of compensatory ventricular
hypertrophy (dogs)
ROlHL-14645-07 Blood flow measurement by ultrasonic
catheter tip methods (human, dogs)
R01HL14717-06 Hemodynamics and heart structure-
Ventricular overload (dogs)
ROlHL-14903-07 A new index of cardiac contractility
(human, dogs, baboons)
P01HL14985-07 0003 Adaptation to hypoxia - Hypoxia
and oxygen transport (human, dogs)
P01HL15194-07 0001 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation, venous
drainage and collateral flow (human, dogs)
ROlHL-15307-06 Central nervous control of renin and
blood pressure (dogs)
ROlHL-16292-05 0002 Surgery and non-obstructive
coronary insufficiency ■ Effects of hypothermia during
cardiopulmonary bypass (dogs)
ROlHL-16292-05 0019 Surgery and non-obstructive
coronary insufficiency - Distortion of subendocardial vessels
in Infant hearts (dogs)
ROIHL- 164 84-04 Radiographic ventriculometry for coronary
heart disease (human)
ROlHL-165 11-04 Sympathetic afferent activity of cardiac
origin (dogs, monkeys)
P60HL-17269-04 0027 National heart and blood vessel
research and demonstration center - Non-invasive
evaluation of cardiac function-lschemic heart disease
(human, dog)
ROlHL-17459-03 Myocardial ischemia (dogs)
P50HL- 17646-04 0010 Study of ischemic heart disease ■
Compliance in ischemic myocardium-Altered cardiac
performance (human, dogs)
P50HL-17648-04 0020 Study of ischemic heart disease ■
Core pathology laboratoiy-lschemlc heart disease (human,
animal)
P50HL-17648-04 0034 Study of ischemic heart disease -
Data management-Hemodynamic data
P50HL-17655-04 0003 Study of ischemic heart disease -
Cardiopulmonary resuscitation (human, dog)
P50HL17655-04 0014 Study of ischemic heart disease ■
Blood flow and gas tension in myocardial ischemia and
infarction (dog, monkey)
P50HL17669-04 0023 Ischemic heart disease center
(SCOR) - Patients with acute myocardial infarction and
myocardial ischemia (human)
P50HL- 176 70-04 0014 Study of ischemic heart disease -
Real time ultrasound imaging in ischemic heart disease
(human, dog)
P50HL-1767004 0015 Study of ischemic heart disease -
Radionuclide studies of myocardial ischemia (human)
ROlHL-17993-04 0002 Ventricular dynamics from
surgically inserted markers - Left ventricle function in
human cardiac allograft
ROlHL-17993-04 0005 Ventricular dynamics from
surgically inserted markers - Cardiac dimensions and
dynamic after mitral, aortic valve surgery (human)
ROlHL-17993-04 0008 Ventricular dynamics from
surgically inserted markers - Exercise after coronary bypass
(human)
ROlHL-18338-04 Computer feedback study of cardiac
muscle mechanics (rats)
Ventricular mechanics in the overloaded
Mechanics of heart muscle contraction
Diastolic properties of the left ventricle
ROlHL-18749-03
heart (dogs)
ROlHL-1891203
(cats, dogs)
ROlHL-19089-03
(human, dogs)
R01HL19246-03 Regression of cardiac hypertrophy -
Myocardial and renal (human)
ROlHL-19391-03 Dynamic determinants of left ventricular
filling (dogs)
ROlHL-19451-03 Functional characteristics of the left
heart
ROlHL-1945103 0001 Functional characteristics of the
left heart - Ventricular performance using epicardial
radiopaque markers (human)
R01HL19451-03 0003 Functional characteristics of the
left heart - Left ventricular segmental contraction (human,
dogs)
ROlHL-19460-03 Mechanics of the papillary muscle and
the left ventricle (cats, rabbits)
POlHL-20552-02 0002 The development and regression of
cardiac hypertrophy ■ Effect of treatment on the
hypertrophied left ventricle (rats)
HEA
POlHL-20552-02 0003 The development and regression of
cardiac hypertrophy - Muscle mechanics of the
hypertrophied left ventricle (rats)
POlHL-20552 02 0004 The development and regression of
cardiac hypertrophy - Ventricular function in experimentally
induced hypertrophy (hogs, sheep, baboons)
ROlHL-20572-02 0001 Hemodynamic relations to
metabolism in hypertension - Hemodynamic and myocardial
functional studies in the SHR (rat)
ROlHL-20629-02 Catheter ventricular defibrillation studies
(dogs)
ROlHL-20895-03 0011 Cineangiographic studies of
cardiovascular system - Ventricular hypertrophy and
preoutflow contraction (human, dogs)
R23HL-21 197-02 Right ventricular contraction and
relaxation (dogs)
ROlHL-2127801 Abnormal cardiac wall motion viewed
ultrasonically (human, dogs, phantoms)
ROlHL-21425-02 Servo-simulated compliance changes-A
reversible Ml (dogs)
Mechanical interactions between ventricle
Cardiac function and metabolism in
R23HL-21462-02
arteries (dogs)
ROlHL-21482-01
diabetes (rats)
ROlHL-21690-02 Sequential multinuclide study of acute
Infarction (human, dogs)
ROlHL-2 1793-02 Functional infarct size by gated
radioangiography (human, dogs)
ROlHL-2 1893-01
(human)
ROlHL-22750-01
Blood volume distribution in hypertension
Digoxin in heart failure with sinus
rhythm (human)
•* R23HL-22787-01 Cardiac volume by biplane
echocardiography (human)
" ROlHL'22894-01 Two dimensional ultrasound and cardiac
surgery (human, dogs)
ROlHL-22917-01 Microvascular pressures in the intact
beating heart (rabbits)
ROlHL-23653-01 Protection of the ischemic myocardium
(dogs)
HEART INNERVATION
SEE NERVOUS SYSTEM AUTONOMIC, HEART INNERVATION
HEART LUNG AND BLOOD RESEARCH REVIEW
COMMITTEES
M POlHL-03174-23 Mechanisms of acute vascular reaction
to injury
M POlHL-04664-18
M P01HL06285 18
biochemistry
M POlHL-06296-18 Cardiovascular and pulmonary
adaptation to stress
M POlHL-06308-18 Mechanisms and therapy of circulatory
disease
M POlHL-06312-17 Surgical cardiology
M POlHL-06314-17 Immunologic mechanisms in
cardiovascular disease
M POlHL-06350-17 Hemostasis research program project
M POlHL-06370-17 Cardiopulmonary and renal pathology
research center
Cardiopulmonary function in remediable
Cardiovascular and lung dynamics
Cardiovascular-respiratory physiology and
P01HL06664-17
vascular disease
P01HL06835-17
POlHL-07896-15
program
POlHL-08214-15
lipids
P01HL08682-15
POlHL-08805-15
circulation
POlHL-08899-14
and disease
POlHL-08974-14
POlHL-09011-15
blood
POlHL-10342-13
and circulation
POlHL-10436-13
heart disease
P01HL-1053912
P01HL-11307-12
cardiology
P01HL11310-12
POlHL-11351-12
Cardiovascular disease
Environmental biomedical research
Chemical and biological properties of
Regulation of the cardiovascular system
Regulation of ventilation and pulmonary
Tolerance to respiratory gases in health
Natural and experimental atherosclerosis
A research and resource program in
The integrated function of respiration
A multidisciplinary study of congenital
Pathophysiology of circulation
Biophysical studies in pediatric
Mechanisms of cardiovascular disease
Cellular and molecular mechanisms of
myocardial function
POlHL-11414-11 Thrombosis and atherosclerosis program
POlHL-11678-11 Cardiovascular dynamics and their
control
POlHL-12157-11 Functions and mechanisms of cell
membrane ion transport
POlHL-12373-10
pathophysiology
POlHL-12738-10
applications
POlHL-1310809
POlHL-13262-07
POlHL-13330-08
POlHL-13480-09
POlHL-13737-07
P01HL13738-08
hearts
'Excludes routine methodology OR covers only general projects which preclude indexing
"Oriented significantly to alwve subject.
at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
Cardiopulmonary physiology and
Physiologic pharmacology and its clinical
Clinical heart transplantation
Arterial wall in atherosclerosis
Mechanical circulatory support
Cardiac electrophysiology
Assisted circulation
Cardiac assist devices and artificial
(contd)
NBA
P0IHL'138SM6 Cyclotron produced isotopas In bialofy
and medicine (human, animals)
PSOHL 14136 07 Pulmonary SCOR Aicvuays obstructive
diseases
POIHL'1438807 Reiulation ol the circulation In
pathological states
POIHL 14414 07 Environmental influences on
cardiorespiratory and cellular functions
POIHL14580 07 Program project in resplratoiy mechanics
Adaptation to hypoxia
Pathophysiology ol cardiopulmonary
P01HL1498507
P01HL15194 07
dysfunction
POIHL 1519504
POIHL 1526505
hyperlipidemias
POIHL 15486 06
POIHL 1559605
hepatitis
POIHL 1583206
lung injury
POIHL 1583506
disease
POIHL 161 1705 Ion movements and membranes in
cardiovascular control
P01HL16118-06 Study of emphysema
Alveolar biology
Membrane-bound enzymes in heart and
Program project in biological materials
Program on surgical control of the
Studies on thrombosis
Coagulation, fibrinolysis, hemostasis and
Chemical-structural piedisposltions to
Study of muscles related to heart
The blood vessel and thrombogenesis
Blood systems in coagulation and vessel
POlHL-16137 05
P01HL1625106
other tissues
P01HL16387-04
POlHL-16411-04
disease
P01HL16607-05 Calcium ion and control of
cardiovascular function
P01HL16683-04 Function and grovnth of cardiac and
skeletal muscle
POIHL 1674805 Cellular and immunological basis of
pulmonary diseases
POlHL-1676905 Pathobiologic and host defense reactions
in the lung
P01HL16833-04 Hemoglobin and red cell system in
hemoglobinopathies
POlHL-16851-04
disease
POlHL-16878-05
disease
P01HL-16910-05
POlHL-17382-05
disorders
POlHL-17419-04
POlHL-17421-05
microcirculation
POlHL-17430-05
POlHL-17731-04
POlHL-17812-04
POlHL-17813-04
blood and tissue
P01HL-17871-04
and hypertension
POlHL-18208-04
rheology
P50HL-18323-04
POlHL-18574-03
applications
POIHL- 1857 5-03
hypertension
POlHL-18576-03
P01HL-18577-03
POlHL-18645-03
atherosclerosis
POlHL-18646-03
POlHL-18708-03
cardiac tissue
POlHL-18827-02
thrombogenesis
P50HL-19153-02
pathogenesis
POlHL-19242-02
POlHL-19259-03
therapy
POlHL-19717-02
POlHL-19737-02
Human red cell membrane in health and
Control of ventilation in health and
Regulation of the peripheral circulation
Chemical mediators of acute pulmonary
Studies on mechanisms of hemostasis
Regulation and exchange in the
Control of coagulation
Physiological basis of pulmonary disease
Thrombosis and plasma proteins
Lung disease and the oxygenation of
Kidney, sodium, cardiac output, arterioles
Center for the study of blood cell
SCOR hypertension center
Lipoprotein methodology and biomedical
Mechanisms of vascular changes in
Thiombosis research program project
Lipoproteins-Cell surface interactions
Biology of the artery wall and
Studies basic to heart transplantation
Oxygen, energy and contractility in
Platelet vessel wall interactions in
SCOR-Pulmonary edemas-Eitology.
Study of vascular smooth muscle
Digoxin-specific antibody in human
Response of the lung to injury
Cellular and molecular aspects of
respiratory physiology
POlHL-20552-02 The development and regression of
cardiac hypertrophy
POlHL-20581-01 Vascular neuroetfector mechanisms in
health and disease
POlHL-2059202 Cell biology of cardiac and skeletal
muscle
POlHL-20948-02
metabolism
POlHL-20984-02
hypertrophy
POlHL-20993-02
atherogenesis
POlHL-20994-02
lung
P50HL-2 1006-02
arteriosclerosis
POlHL-21016-02 Sickle cell anemia and other
hemoglobinopathies
POlHL-21584-02 Respiratory mechanics in normal and
abnormal states
Molecular basis of cholesterol
Cellular mechanisms in cardiac
Population dynamics of arterial cells In
Dynamics of neutrophil elastase in the
Specialized center of research in
271
M POIHL 22602 01 Pathophysiology of the endothelium
M POIHL 22619 01 Cellular mechanisms of heart failure
M PniHl 22633 01 Cellular and molecular biology of
lipoprotein metabolism
** ROlHl-23201 01 Mechanisms ol hypertension (human,
rats)
HEART-LUNG BYPASS
SEE CARDIOVASCUUR SURGERY. CIRCUUTORY ASSIST,
HEARI LUNG BYPASS
HEART-LUNG MACHINE
SEE CARDIOVASCULAR SURGERY. CIRCULATORY ASSIST.
HEART MECHANICAL EXTRACORPOREAL
HEART MASSAGE
SEE HEART RESUSCITATION. HEART MASSAGE
HEART MECHANICAL EXTRACORPOREAL
SEE CARDIOVASCULAR SURGERY. CIRCULATORY ASSIST.
HEART MECHANICAL EXTRACORPOREAL
HEART MOTION
SEE HEART FUNCTION. HEART MOTION
HEART MURMURS
SEE HEART DISORDERS. VALVULAR
HEART MUSCLE
SEE HEART. MYOCARDIUM
HEART MUSCLE, PAPILLARY
SEE HEART. PAPILLARY MUSCLES
HEART OUTPUT
SEE HEART FUNCTION. CARDIAC OUTPUT
HEART PACEiMAKERS
SEE HEART. CONDUCTION SYSTEM. HEART PACEMAKERS
HEART PACEMAKERS ELECTRONIC
** ROlHL-04666-19 Artificially paced hearts-Technology,
physiology (human, dogs)
POlHL-08682-15 0027 Regulation of the cardiovascular
system - Cardiac mechanoreceptors -Reflex regulation of
renal function (dogs)
** POlHL-11310-12 0071 Mechanisms of cardiovascular
disease - Electrophysiological studies of atrial flutter
(human) .
** P01HL113 10-12 0072 Mechanisms of cardiovascular
disease Electrophysiological studies of atrial tachycardia
with block (human)
** POlHL-11310-12 0073 Mechanisms of cardiovascular
disease ■ Electrophysiological study of atrial fibrillation
(human)
** POlHL-1 1310-12 0076 Mechanisms of cardiovascular
disease - Tratment of depressed cardiac output following
heart surgery (children, puppies)
POlHL-1 13 10-12 0077 Mechanisms of cardiovascular
disease - Abnormalities of rhythm and conduction following
heart surgeiy (human)
ROlHL-11907-08 Mechanisms of physiological responses
to exercise (human, dogs)
POlHL-12738-10 0035 Physiologic pharmacology and its
clinical applications - Function and dysfunction of the
sinoatrial node (human)
POlHL-12738-10 0098 Physiologic pharmacology and its
clinical applications - Skeletal muscle support of the
chronically failing heart (dogs)
POlHL-12738-10 0132 Physiologic pharmacology and its
clinical applications - Coronary occlusions and arrhythmias
(dogs)
** POlHL-13108-09 0017 Clinical heart transplantation -
Electrophysiology of the transplanted denervated human
heart
POlHL-13108-09 0018 Clinical heart transplantation -
Electrophysiologic studies of cardiac drugs in the
denervated heart
** ROlHL-13988-07 Elimination of reoperative cardiac
pacemaker surgery (dogs)
ROlHL-15190-07 Physiological basis of arrhythmias and
their therapy (human)
** ROlHL-15247-05 Extending the life of implanted
pacemakers (dogs, human)
ROlHL-16760-05 Dynamic control of coronary blood flow
(dogs)
P50HL- 176 48-04 0018 Study of ischemic heart disease -
Myocardial damage-Infarction vectors recalled by
premature atrial stimulation
P50HL-17651-04 0023 Ischemic heart disease specialized
center of research - Development of multipurpose catheter
for monitoring and electronic pacing
ROlHL-18794-04 Prospective studies of conduction disease
(human)
** ROlHL-20077-02 External cardiac stimulation with
microwave radiation (dogs)
** ROlHL-20238-02 Prospective bundle branch block study
(human)
ROlHL-20597-02 Electrophysiologic correlates of
myocardial ischemia (human, dogs, rabbits)
** ROlHL-21632-02 Development of a transcutaneous power
transfer system (cattle)
•Excludes routine melhodotogy OR covers only general projects which preclude
**Orw<ited significantly to above subject.
ROlHL-21872-01
heart (dogs)
indexing at the specific level.
Myocardial perfusion in the hypertrophied
HEA
HEART PACEMAKERS ELECTRONIC, CAROTID
STIMULATORS
PPlHt 06285 18 0182 Cardiovascular respiratory
physiology and biochemistry Structure and function of
vascular chemoieceplois (cats, rats)
P50HL 1/648 04 0016 Study of ischemic heart disease
Intraventricular conduction- Effect ol pacing on conduction
and automaticity
HEART PRESERVATION
M POIHL 063 12 17 Surgical cardiology
POIHL 1310809 0001 Clinical heart transplantation
Therapy and prognosis (human)
POIHL 18646 03 0009 Studies basic to heart
transplantation Pathologic aspects of cardiac allograft
reiection (sheep, dogs)
" ROIHL 1893602
studies (rat)
*• R01HL2021902
(rats)
R23HL-22448-01
perfusion (rats)
Heart preservation and transplantation
Cryopreservation of the isolated heart
Modulation ol heart graft antigenicity by
Total
M
M
HEART PROSTHESIS
SEE ALSO HEART PACEMAKERS ELECTRONIC
•* POlHL-06312 17 0030 Surgical cardiology
artificial heart (calves)
P01HL0637017 0014 Cardiopulmonary and renal
pathology research center Quantitative morphology in
cardiac disease (human, rats, dogs)
** P01HL10436 13 0006 A multidisciplinary study of
congenital heart disease Ventricular blood pumps and
valves (human, cattle)
ROIHL 11418-09 Poly-diaminophosphazenes
•* ROlHL-12307 08 Non-surgical treatment of congenital
heart disease (human, dogs)
POlHL-1273810 0094 Physiologic pharmacology and its
clinical applications - Ventricular function and structure
(human, dogs)
POlHL-13330-08 Mechanical circulatory support
POlHL-13330-08 0031 Mechanical circulatory support
Hemodynamics of cardiac prosthesis
POlHL-13330-08 0034 Mechanical circulatory support In
vivo test and evaluation of left ventricular bypass pumps
(human, cattle)
POlHL-13330-08 0056 Mechanical circulatory support
Blood compatibility linings (calves)
POlHL-13330-08 0059 Mechanical circulatory support -
Physiologic evaluation of circulatory assistance (cattle)
POlHL-13330-08 0062 Mechanical circulatory support ■
CORE facilities
POlHL-13737-07 0024 Assisted circulation - Dynamic
prosthetic myocardium (dogs)
POlHL-13737-07 0026 Assisted circulation - Hemostatic
mechanism (human, dogs)
POlHL-13737-07 0033 Assisted circulation - Autologous
bioprosthetic grafts for coronary artery bypass surgery
(human, dogs)
POlHL-13738-08 Cardiac assist devices and artificial
hearts
POlHL-13738-08 0001 Cardiac assist devices and
artificial hearts - Cardiac assist devices (human, sheep)
POlHL-13738-08 0002 Cardiac assist devices and
artificial hearts - Total replacement with artificial heart
(calves, sheep, ponies)
POlHL-13738-08 0003 Cardiac assist devices and
artificial hearts - Pathophysiological effects of the artificial
heart (calves)
POlHL-13738-08 0004 Cardiac assist devices and
artificial hearts ■ Hematological evaluation of prosthetic
materials (calves)
POlHL-13738-08 0005 Cardiac assist devices and
artificial hearts - Development of new materials for
artificial heart and assist devices (sheep, dog)
R01HL17821-03 Cavitation phenomena near prosthetic
devices
ROlHL-18084-03 Artificial heart and related problems
(calves)
POlHL-18576-03 0013 Thrombosis research program
project - Early warning and monitoring test systems in
thrombotic disease (human)
' ROlHL-203 56-02 Development and evaluation of an
artificial heart (calves)
ROlHL-2 1948-01 Capillary, tissue volume and lymph flow
in lung edema (sheep, cattle)
* ROlHL-22329-01 Active prosthetic myocardium -Effects on
LV function (dogs)
ROlHL-23899-01 Flow and flexing at blood/biomaterial
intertaces
' NOlHV-12017-15 Fabrication of grafted hydrogel coatings
for plastic heart assist devices
* NOlHV-12054-14 Development of intimal linings (human,
cattle)
* NOlHV-12065-16 Fabrication of implantable artificial heart
devices (animals)
NOlHV-32913-11 Study electrodeless glow discharge for
modifying polymer surface
* NOlHV-32959-10
devices
* NOlHV-42914-13
(cattle)
NO lHV-729 19-01
divices
Development of materials for heart assist
Solenoid left ventricular assist system
Test polymers for circulatory assist
(contd)
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
HEA
** NOlHV-72933-01 Electrical energy transmission technique
development (dogs)
** NOlHV-7293401 Development ot a left heart assist blood
pumps (human, cattle)
** NOlHV-72937-00 Left heart assist blood pumps (calves)
** NOlHV-72939-01 Develop and evaluate left heart assist
blood pumps (human, calves, pigs)
•* N01HV-72975-D2 Energy converter for left ventrical assist
devices (calves)
** NOlHV-81388-20 Microfiber substrate for growth of intimal
linings in circulatory assist devices
HEART PROSTHESIS, AUXILIARY
SEE ALSO CARDIOVASCULAR SURGERY, CIRCUUTORY
ASSIST, HEART MECHANICAL EXTRACORPOREAL
M POlHL-13737-07 Assisted circulation
** P01HL13737-07 0002 Assisted circulation - U-shaped
mechanical auxiliary ventricle (dogs)
** P01HL13737-07 0006 Assisted circulation ■ Portable
driving unit for permanent assist devices (dogs)
POlHL-13737-07 0024 Assisted circulation - Dynamic
prosthetic myocardium (dogs)
P01HL13737-07 0027 Assisted circulation ■ Optimization
of cardiac assistance (dogs)
** POlHL-13737-07 0032 Assisted circulation - The dynamic
aortic patch (human, dogs)
** NOlHV-4296007 Development and evaluation of cardiac
prostheses (calves)
** NOlHV-53006-06 Evaluation of model VII left ventricular
assist device (human)
** NOlHV-53008-07 Left ventricular assist device -Clinical
evaluation (human)
HEART PROSTHESIS, AUXILIARY, AORTIC
BALLOON PUMPING
ROlHL-05875-18 Pathologic metabolic and physiologic
studies of heart (human, dogs, cats)
** POlHL-06312-17 0041 Surgical cardiology ■ A
servomechanism for left ventricular assist (human, dogs,
sheep)
P01HL07896-15 0054 Environmental biomedical research
program - Myocardial effects of hemorrhagic shock (dogs)
** POlHL-12738-10 0071 Physiologic pharmacology and its
clinical applications - lABP patient management in
ventricular power failure (human)
** P01HL1273810 0092 Physiologic pharmacology and its
clinical applications - Subendocardial ischemia following
open heart surgery (human)
P01HL1273810 0123 Physiologic pharmacology and its
clinical applications - Ventricular assistance and
preservation (human, dogs)
" POlHL-12738-10 0124 Physiologic pharmacology and its
clinical applications - Counterpulsation on myocardial
ischemia measured by carbon dioxide tension (dogs)
** POlHL-13330-08 0034 Mechanical circulatory support ■ In
vivo test and evaluation of left ventricular bypass pumps
(human, cattle)
** P01HL13330-08 0059 Mechanical circulatory support ■
Physiologic evaluation of circulatory assistance (cattle)
** POlHL-13737-07 0007 Assisted circulation -
Determination of cardiac status by use of balloon pump
(dogs)
** POlHL-13737-07 0008 Assisted circulation - Phase-shift
balloon pumping alternate designs
POlHL-13737-07 0009 Assisted circulation - Analytical
models
** POlHL-13737-07 0025 Assisted circulation • Driving
system based on quantitative criteria (human, dogs)
** POlHL-13737-07 0026 Assisted circulation - Hemostatic
mechanism (human, dogs)
** P01HL13737-07 0027 Assisted circulation - Optimization
of cardiac assistance (dogs)
POlHL-13737-07 0028 Assisted circulation ■ Clinical
studies of intraaortic balloon pumping
** POlHL-13737-07 0029 Assisted circulation - Chronic left
ventricular failure (human)
** POlHL-13737-07 0030 Assisted circulation ■ Myocardial
ischemia-Effects of phase-shift balloon pumping (dogs)
** POlHL-13737-07 0031 Assisted circulation ■ Myocardial
ischemia-Biochemical changes (dogs)
** P01HLI373707 0034 Assisted circulation - Phasic aortic
flow and cardiac output from phasic pressures (dogs)
P01HL13737-O7 0036 Assisted circulation - Assessment
of infarct size from hemodynamic measurements
** POlHL-13737-07 0038 Assisted circulation -
Distinguishing the ischemic ventricle from scarred ventricle
by balloon pumping
** P01HL13737-07 0039 Assisted circulation • Computer
controlled intraortic balloon pumping
POlHL-13738-08 0001 Cardiac assist devices and
artificial hearts - Cardiac assist devices (human, sheep)
ROlHL-14571-05 Myocardial preservation and coronary
reperfusion (baboons, dogs)
R01HL-I4644-05 Optimization diastolic augmentation and
systolic sink (dogs)
ROlHL-15522-06 Influence of mannitol on ischemia
cardiac muscle (dogs, cats, rats)
P60HL-1 7269-04 0029 National heart and blood vessel
research and demonstration center - Clinical application of
circulatory assistance (human)
** P60HL17269-04 0030 National heart and blood vessel
research and demonstration center • Cardiovascular
engineering laboratories (human)
272
** P50HL17648-04 0011 Study of ischemic heart disease •
Surgical treatment for acute myocardial ischemia (human,
dogs)
** P50HL 1766504 0001 Study of ischemic heart disease -
Reduction of acute anterior myocardial infarction-
Mechanical circulatory assist
P50HL-17665-04 0003 Study of ischemic heart disease -
Quantitation of injury -Acute myocardial infarction
complicated by shock (human)
** P50HL-17669-04 0012 Ischemic heart disease center
(SCOR) - Circulatory assistance (human, dog)
ROlHL'17821-03 Cavitation phenomena near prosthetic
devices
ROlHL-18190-03 Myocardial blood flow in acute
myocardial infarction (human, dogs)
ROlHL-19030-03 Tissue protection during circulatory
interruption (dogs)
ROlHL-19414-03 Protection of myocardium during cardiac
surgery (dogs, cats, human)
ROlHL-20356-02 Development and evaluation of an
artificial heart (calves)
** ROlHL-20803-02 Infra-aortic balloon pumping (dogs,
lambs, cats)
ROlHL-21684-02 0001 Radionuclide infarct sizing and
therapy evaluation - Evaluating preservation of ischemic
myocardium by radioisotope methods (dog)
** ROlHL-22274-01 Quantitating in series effects in cardiac
arrhythmias (dogs)
HEART PROSTHESIS, VALVES PROSTHETIC
ROlHL-05694-20 Functional pathology of cardiovascular
disease (human)
POlHL-06312-17 0043 Surgical cardiology - The
cylindrical ventricular assist device (dogs)
P01HL-0e370-17 0014 Cardiopulmonary and renal
pathology research center - Quantitative morphology In
cardiac disease (human, rats, dogs)
" POlHL-1043613 0006 A multidisciplinary study of
congenital heart disease - Ventricular blood pumps and
valves (human, cattle)
POlHL-12373-10 0003 Cardiopulmonary physiology and
pathophysiology - Myocardial function in man
POlHL-1237310 0020 Cardiopulmonary physiology and
pathophysiology - Hospitalization and patient care
POlHL-13330-08 0031 Mechanical circulatory support -
Hemodynamics of cardiac prosthesis
POlHL-13330-08 0056 Mechanical circulatory support -
Blood compatibility linings (calves)
POlHL-13330-08 0062 Mechanical circulatory support -
CORE facilities
POlHL-13738-08 0001 Cardiac assist devices and
artificial hearts - Cardiac assist devices (human, sheep)
** ROlHL-13803-07 Advanced cardiac valvular and vascular
prosthesis (dogs, baboons)
P01HL14388-07 0217 Regulation of the circulation in
pathological states - Fluid mechanics of aortic flow (dogs,
human)
** ROlHL-16461-05 Late results of valve replacement-
Computer analysis (human)
ROlHL-16935-05 Tissue organization and turnover in the
semilunar valve (dogs, rats)
** P60HL17269-04 0032 National heart and blood vessel
research and demonstration center - Clinical circulatory
assist device fabrication
ROlHL-17821-03
devices
** ROlHL-17859-04
dynamics
** ROlHL-17969-04
valves (dogs)
ROlHL-18441-03
substitutes
ROlHL-194 14-03 Protection of myocardium during cardiac
surgery (dogs, cats, human)
** R01HL-20037-02 Left ventricular-aortic bypass and
composite prosthesis (sheep, swine, cattle)
** ROlHL-20829-02 Fluid mechanics of heart valve
prostheses (dogs, human)
ROIHL-22627-01 An inhibitor of platelet adhesion to
artificial organs (human)
** ROlHL-22888-01 Prosthetic valve endocarditis-Etiology
and therapy (dogs)
HEART RATE
SEE HEART FUNCTION, HEART RATE
HEART RESUSCITATION
SEE ALSO HEART PACEMAKERS ELECTRONIC
P60HL-1 7269-04 0036 National heart and blood vessel
research and demonstration center • Public education
** P50HL-17655-04 0003 Study of ischemic heart disease -
Cardiopulmonary resuscitation (human, dog)
** ROlHL-18800-04 Prospective study of resuscitated sudden
death victims (human)
ROlHL-18805-04 0004 Sudden cardiac death and the
onset of myocardial infarction - Sudden death survivors-
Clinical follow-up and therapy (human)
ROlHL-19203 03 Surgical approach to congenital heart
diseases (dogs, primates)
HEA
Cavitation phenomena near prosthetic
Computational methods in cardiac fluid
Function and structure of semilunar
Guidelines for polymers acting as elastin
HEART RESUSCITATION, ELECTRIC
COUNTERSHOCK
** ROlHL-1607606 Electrophyslology of fibrillation and
defibrillation (human)
** ROlHL-1804004
(calves)
** ROlHL-20629-02
Waveform dependency In defibrillation
Catheter ventricular defibrillation studies
(dogs)
** R01HL-21038-01 Electrically induced cardiac EM-
histochemical changes (animals)
** ROlHL-2 16 74-01 Development of automatic implanted
defibrillator (dogs, cattle)
** ROlHL-22699-01 Defibrillation electrode studies (dogs,
swine)
HEART RESUSCITATION, HEART MASSAGE
** P50HL- 17655-04 0003 Study of ischemic heart disease •
Cardiopulmonary resuscitation (human, dog)
HEART REVASCULARIZATION
** NOlHI-72947-01 Coordination center-Coronary intervention
POlHL-06296-18 0003 Cardiovascular and pulmonary
adaptation to stress - Human exercise studies (human,
dogs)
POlHL-13738-08 0001 Cardiac assist devices and
artificial hearts - Cardiac assist devices (human, sheep)
ROlHL-14378-07 Lipemias and reconstructive cardiac
surgery (human)
** ROlHL-14571-05 Myocardial preservation and coronary
reperfusion (baboons, dogs)
ROlHL'16484-04 Radiographic ventrlculometry for coronary
heart disease (human)
** P50HL- 17646-04 0013 Study of ischemic heart disease -
Maintenance of myocardial vascular integrity after
revascularization (dogs)
P50HL-17665-04 0005 Study of ischemic heart disease -
Evaluation of zone of jeopardized myocardium in patients
with angina pectoris
P50HL-17665-04 0026 Study of ischemic heart disease -
Anesthesia -Myocardial ischemia and hemodynamics in
coronary disease (human)
PSOHL-17669-04 0023 Ischemic heart disease center
(SCOR) - Patients with acute myocardial infarction and
myocardial ischemia (human)
** ROlHL-17759-03 Studies of myocardial reactive hyperemia
(dogs, human)
ROIHL- 18460-01 Effects of prolonged hypoperfusion on the
myocardium (rabbits)
ROlHL-1903003 Tissue protection during circulatory
interruption (dogs)
ROlHL-1907203 Modification of tissue injury in
myocardial infarction (dogs, human)
ROlHL-19182-03 Surgical aspects of myocardial
hypertrophy (dogs)
ROlHL-19275-03 Characterization of collateral blood
vessels (dogs)
ROlHL-19414-03 Protection of myocardium during cardiac
surgery (dogs, cats, human)
ROlHL-19673-03 Surgical aspects of shock and hypoxia
(dogs, monkeys, rats)
ROlHL-20895-03 0003 Cineangiographic studies of
cardiovascular system - Densitometry in coronary stenosis
(human)
** ROlHL-20895-03 0008 Cineangiographic studies of
cardiovascular system - Intercoronary anastomotic
circulation-Stenosis and occlusion (dogs)
ROlHL-2127801 Abnormal cardiac wall motion viewed
ultrasonically (human, dogs, phantoms)
** ROlHL-22005-01 Intermittent retroperfusion of ischemic
myocardium (dogs)
** ROlHL-22098-01 Is postoperative infarction due to
reperfusion injury? (human, dogs)
** ROlHL-22759-01 Regional myocardial blood flow during
hypothermia (dogs)
** ROlHL-228 15-01 Regional myocardial function after
revascularization (dogs)
** NOlHV-32973-12 Coordinating center for collaborative
studies on coronary artery surgery
** NOlHV-32975-08 Collaborative studies on coronary artery
surgery (human)
NOlHV-32976-09
surgery (human)
NOlHV-32978-08
surgery
NOlHV-32979-09
surgery
NOlHV-32980-07
surgery (human)
NOlHV-32981-10
surgery (human)
NOlHV-32983-11
surgery (human)
NOlHV-32984-10
surgery (human)
NOlHV-32985-11
surgery (human)
Collaborative studies on coronary artery
Collaborative studies on coronary artery
Collaborative studies on coronary artery
Collaborative studies on coronary artery
Collaborative studies on coronary artery
Collaborative studies on coronary artery
Collaborative studies on coronary artery
Collaborative studies on coronary artery
HEART REVASCULARIZATION, CORONARY
BYPASS
M P01HL-04664-18 Cardiovascular and lung dynamics
POlHL-04664-18 0001 Cardiovascular and lung dynamics
■ X-ray projection image videodensitometry (dogs)
(contd)
'Excludes routine methodology OR cavers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
HEA
POIHI 04664 18 0003 Catdiovisculii tnd lung dynamics
Xarsy pfojedion image videometry (human, dogs)
POIHl 04664 18 0010 Cardiovasculat and lung dynamics
Lett wentriculai dynamics (human)
POIHI'04664 18 0011 Cardiovascular and lung dynamics
Dateclion ot abnormal segments of the human ventricle
by measure ol asynergy
POIHI.04664 18 0012 Cardiovascular and lung dynamics
Quantitative single plane lett ventricular angiography
(human)
PC1HL04664 18 0013 Cardiovascular and lung dynamics
Ventricular lunction in coronary disease using NTG and
ventriculograms (human)
** POIHI 0466418 0014 Cardiovascular and lung dynamics
Clinical application o( computer analysis ol ventricular
wall motion
** POlHL-0628518 0156 Cardiovascular respiratory
physiology and biochemistry Myocardial perlormance
following revascularisation (human)
M (^1HL06312 17 Surgical cardiology
** PO1HL06312 17 0013 Surgical cardiology Aortocoronary
vein bypass grafting (human)
** P01HL06312 17 0015 Surgical cardiology Internal
mammary artery versus saphenous vein tor coronary artery
bypass (human)
" P01HL06312 17 0030 Surgical cardiology Total
artificial heart (calves)
P01HL06312 17 0053 Surgical cardiology Enzyme
pattern following cardiac surgery (human)
P01HL0631417 0065 Immunologic mechanisms in
cardiovascular disease - Transplantation biology and
clinical transplantation
POlHL-0868215 0005 Regulation of the cardiovascular
system - Smooth muscle and mechanical properties of
blood vessels (dogs, human)
** ROlHL-09315-15 Coronary insufficiency and myocardial
revascularization (human, dogs)
POlHL-1131012 0057 Mechanisms of cardiovascular
disease • Blood pressure reduction after heart surgery in
adults (human)
P01HL1131012 0081 Mechanisms of cardiovascular
disease - Analysis of regional left ventricular function
(human)
P01HL1310809 0018 Clinical heart transplantation ■
Electrophysiologic studies of cardiac drugs in the
denervated heart
M PO1HL13737-07 Assisted circulation
** POlHL-13737-07 0033 Assisted circulation - Autologous
bioprosthetic grafts for coronary artery bypass surgery
(human, dogs)
** P01HL1373707 0037 Assisted circulation - Clinical
measurement of blood flow through aorto-coronary vein
bypass graft
** POlHL-13737-07 0038 Assisted circulation ■
Distinguishing the ischemic ventricle from scarred ventricle
by balloon pumping
P01HL15194-07 0001 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation, venous
drainage and collateral flow (human, dogs)
POlHL-15194-07 0017 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation and
effects of arteriographic lesions on flow (human)
** POlHL-15194-07 0019 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation, bypass
grafts and diastolic driving pressure (human, dogs)
** ROlHL-15676-06 The role of occult myocardial failure in
human shock (human, dogs)
ROlHL-15681-06 Coronary flow studies of partially
obstructed vessels (dogs)
R01HL17246-03 Oxygen uptake at one minute of exercise
(human)
P60HL-17269-04 0026 National heart and blood vessel
research and demonstration center ■ Dynamics of ischemic
heart disease (human, dog)
P60HL17269-04 0029 National heart and blood vessel
research and demonstration center - Clinical application of
circulatory assistance (human)
** P50HL- 17648-04 0011 Study of ischemic heart disease -
Surgical treatment for acute myocardial ischemia (human.
dogs)
** P50HL-17648-04 0012 Study of ischemic heart disease -
Retrograde coronary venous perfusion-Acute myocardial
ischemia
** P50HL-1 7648-04 0013 Study of ischemic heart disease ■
Fate of bypassed and bypassing vessels (dogs)
** P50HL-17651-04 0032 Ischemic heart disease specialized
center of research - Cardiovascular surgery core (human,
dogs)
P50HL-17651-04 0036 Ischemic heart disease specialized
center of research - Core facilities-Cardiovascular
pathology (human, dog)
** P50HL17651-04 0044 Ischemic heart disease specialized
center of research - Limb blood flow after myocardial
revascularization (human)
P50HL-17655-04 0004 Study of ischemic heart disease -
Coronary arteriography in survivors of acute myocardial
infarction (human)
" P50HL- 17655-04 0006 Study of ischemic heart disease ■
Evaluation of coronary artery bypass graft surgery (human)
** P50HL-1 7655-04 0009 Study of ischemic heart disease -
Random trial of medical and surgical therapy in unstable
angina (human)
273
P50HI 17655 04 0011 Study of ischemic heart disease
Core facility Cardiovascular nuclear medicine (human, dog)
P50HL 17665 04 0013 Study of ischemic heart disease
National cooperative study in unstable angina pectoris
(human)
P50HI 17665 04 0021 Study of ischemic heart disease
Identification, prevention Myocardial ischemia in
cardiopulmonary bypass (dog)
P50HI 17665 04 0022 Study ol ischemic heart disease
Effect of coronary revascularization on left ventricular
function (human)
P50HL 17667 04 0001 Study of ischemic heart disease
Natural history of ischemic heart disease (human)
P50HL 1766704 0019 Study of ischemic heart disease •
Assessment of long term results of coronary artery bypass
grafting (human)
P50HL 1766704 0022 Study of ischemic heart disease
Preventing myocardial injury in surgery using
cardiopulmonary bypass (human, rat)
' P50HL 17670-04 0006 Study of ischemic heart disease
Assessment of coronary artery hemodynamics and
myocardial blood flow (human)
P50HL- 176 70-04 0008 Study of ischemic heart disease
Surgical treatment of cardiac rhythm disorders (human.
dogs)
P50HL 17670-04 0016 Study of ischemic heart disease -
Core pathology laboratory (human, dogs, monkeys)
P50HL 17670-04 0017 Study of ischemic heart disease •
Core enzymology laboratory (human)
P50HL 17670-04 0020 Study of ischemic heart disease -
Radionuclide evaluation of coronary artery disease (human.
dog)
* P50HL-17682-04 0003 Study of ischemic heart disease ■
Effects of myocardial revascularization in man
* P50HL-1 768204 0008 Study of ischemic heart disease -
Clinical core unit
R01HL17759-03 Studies ot myocardial reactive hyperemia
(dogs, human)
* ROlHL-17895-04 Myocardial function and metabolism
following ischemia (rats)
* ROlHL-17993-04 0001 Ventricular dynamics from
surgically inserted markers ■ Effects of aortocoronary
bypass graft surgery on ventricular function (human)
* R01HL17993-04 0002 Ventricular dynamics from
surgically inserted markers - Lett ventricle function in
human cardiac allograft
ROlHL-17993-04 0003 Ventricular dynamics from
surgically inserted markers - Effects of pharmacologic
agents on left ventricular dynamics (human)
'* ROlHL-17993-04 0004 Ventricular dynamics from
surgically inserted markers - Exercise training following
coronary artery bypass graft surgery (human)
'* ROlHL-17993-04 0007 Ventricular dynamics from
surgically inserted markers Digitalis after coronary artery
surgery (human)
'* ROlHL-17993-04 0008 Ventricular dynamics from
surgically inserted markers - Exercise after coronary bypass
(human)
'* P50HL 18323-04 0046 SCOR hypertension center -
Coronary artery bypass surgery -Associated hypertension
(human)
ROlHL-18398-04 Mechanisms of delayed and asymetric
ventricular conduction (human, dogs)
POlHL-18645-03 0006 Biology of the artery wall and
atherosclerosis The platelet and atherosclerosis (monkeys,
baboons)
ROlHL-18783-04 Detection and control of ventricular
premature beats (human)
ROlHL-18805-04 0003 Sudden cardiac death and the
onset of myocardial infarction - Prediction from clinical and
laboratory assessments (human)
** ROlHL-18907-03 Objective evaluation early after Ml and
heart surgery (human)
** ROlHL-20163-02 Competitive coronary flow in native and
graft vessels (dog)
ROlHL-20630-03 Development of a pulsed Doppler velocity
detector (human, animals)
ROlHL-20895-03 0002 Cineangiographic studies of
cardiovascular system - Coronary disease-Regional
myocardial blood flow (human, dog)
ROlHL-20895-03 0003 Cineangiographic studies of
cardiovascular system - Densitometry in coronary stenosis
(human)
ROlHL-20895-03 0008
cardiovascular system
Cineangiographic studies of
Intercoronary anastomotic
circulation-Stenosis and occlusion (dogs)
R23HL-21292-01 Human ventricular activation-Patterns
and mechanisms (human)
ROlHL-21293-02
surgery (human)
Randomized study of coronary bypass
Platelet inhibitor drug in coronary surgery
ROlHL-21533-02
(human)
R23HL-22004-01 Imaging and ECG studies in acute and
chronic IHO (human)
ROlHL-22098-01 Is postoperative infarction due to
reperfusion injury? (human, dogs)
ROlHL-22445-01 Platelet inhibitors-Effect on coronary
bypass grafts (dogs)
ROlHL-22815-01 Regional myocardial function after
revascularization (dogs)
NOlHV-32974-09 Collaborative studies on coronary artery
surgery (human)
HEA
HEART RHYTHM
Sff HtARI fUNCTION. HEART RHYTHM
HEART SCANNING
SfE HtARI VISUAIIZATION. HEART SCANNING*
HEART SEPTA
SEE HEART. SEPTUM
HEART SEPTAL DEFECTS
SEE CONGENITAL ABNORMALITIES. HEART SEPTAL DEFECTS
HEART SIZE
SEE HEART DIMENSIONS AND WEIGHT
HEART SOUND MEASUREMENTS
SEE HEART DISORDERS DIAGNOSIS. HEART SOUND
MEASUREMENTS-
HEART SOUNDS
SEE HEART FUNCTION, HEART SOUNDS
HEART SURGERY
SEE ALSO HEART PROSTHESIS
SEE ALSO HEART RESUSCITATION
SEE ALSO HEART REVASCULARIZATION
SEE ALSO HEART TRANSPUNTATION
POIHL 04664 18 0003 Cardiovascular and lung dynamics
X-ray projection image videometry (human, dogs)
POlHL-06296-18 0003 Cardiovascular and pulmonary
adaptation to stress ■ Human exercise studies (human,
dogs)
M POlHL-06312-17 Surgical cardiology
•* POlHL-06312-17 0013 Surgical cardiology Aortocoronary
vein bypass grafting (human)
** POlHL-06312 17 0015 Surgical cardiology Internal
mammary artery versus saphenous vein for coronary artery
bypass (human)
** P01HL06312 17 0016 Surgical cardiology • Effect of
hydralazine on infarct size following coronary occlusion
(human)
** POlHL-06312-17 0017 Surgical cardiology - Cardiac
transplantation (human)
** POlHL-06312-17 0018 Surgical cardiology ■ Cardiac
transplantation growth (calves)
** P01HL06312-17 0021 Surgical cardiology - Cardiac
transplantation-Effect of immunosuppression on
atherogenesis (monkeys)
** POlHL-06312-17 0023 Surgical cardiology - Effect of
denervation on atherosclerosis
POlHL-06312-17 0028 Surgical cardiology - Coronary flow
in the transplanted denervated heart (dogs)
POlHL-06312-17 0029 Surgical cardiology - Cardiac
lymphatics in the transplanted heart (dogs)
** POlHL-06312-17 0039 Surgical cardiology - Cardiac
transplantation-Biopsy correlates of rejection
** POlHL-06312-17 0053 Surgical cardiology - Enzyme
pattern following cardiac surgery (human)
ROlHL-07605-16 Congenital heart disease research
program (human, dogs)
ROlHL-09474-11 Natural history-congenital heart defects-
Joint study (human)
ROlHL-09476-10 Natural history, congenital heart defects-
Joint study
M POlHL-10436-13 A multidlsclplinary study of congenital
heart disease
** POlHL-10436-13 0001 A multldiscipllnary study of
congenital heart disease - Assessment of the outlook for
children with congenital heart disease
•* POlHL-10436-13 0005 A multidlsclplinary study of
congenital heart disease - Pulmonary physiology In
congenital heart disease (human)
POlHL-10436-13 0008 A multidlsclplinary study of
congenital heart disease - Physiologic consequences of
chronic hypoxemia (human)
R01HL10718-10 Natural history of congenital heart
defects-Joint study (human)
M POlHL-11310-12 Mechanisms of cardiovascular disease
" POlHL-11310-12 0053 Mechanisms of cardiovascular
disease - Ventricular pressure-volume after cardipulmonary
bypass (dogs)
** POlHL-1 1310-12 0054 Mechanisms of cardiovascular
disease - Mathematical model of ventricular pressure-
volume (human, dogs)
** POlHL-11310-12 0055 Mechanisms of cardiovascular
disease - Ventricular pressure-volume after Intracardiac
surgery (human)
** POlHL-1 1310-12 0056 Mechanisms of cardiovascular
disease - Cardiac output response to blood pressure
reduction in Infants (human)
** POlHL-11310-12 0057 Mechanisms of cardiovascular
disease Blood pressure reduction after heart surgery in
adults (human)
** POlHL-1 1310-12 0058 Mechanisms of cardiovascular
disease - Dynamic response to vasodilating agents
postoperatively (human)
** POlHL-11310-12 0059 Mechanisms of cardiovascular
disease - Contractility-Acute response to diogoxin after
heart surgery (children)
** POlHL-11310-12 0062 Mechanisms of cardiovascular
disease - Myocardial depressant factor in postoperative
cardiac dysfunction (human, dogs)
(contd)
•Excludes routine methodology OR covers only general projects whicii preclude indexing at the specific level.
**0nented significantly to above subject.
M Grant has subprajeds describing specific research aspects.
See Appendix for investigator's name and grant number
HEA
' POlHL-11310-12 0063 Mechanisms of cardiovascular
disease ■ Myocardial function, metabolism and cellular
integrity after heart surgery (dogs)
' P01HL-U310-12 0065 Mechanisms of cardiovascular
disease - Algorithms for arterial pressure by automatic
vasoactive agents control (human)
' POlHL'l 1310-12 0066 Mechanisms of cardiovascular
disease - Measurement of cardiac output by thermodilution
(children)
' POIHLI 131012 0067 Mechanisms of cardiovascular
disease - Cardiac performance with measured
hemodynamic variables (human)
' POlHL-l 1310-12 0068 Mechanisms of cardiovascular
disease - Pharmacological intervention and myocarcial
oxygen consuption (human, dogs)
' POlHL-11310-12 0069 Mechanisms of cardiovascular
disease - Factors affecting mortality and morbidity after
heart surgery (human)
' POlHL-11310-12 0070 Mechanisms of cardiovascular
disease - Factors affecting long-term mortality and
morbidity after heart surgery (human)
' POlHL-l 1310-12 0071 Mechanisms of cardiovascular
disease - Electrophysiological studies of atrial flutter
(human)
' POlHL-11310-12 0072 Mechanisms of cardiovascular
disease - Electrophysiological studies of atrial tachycardia
with block (human)
' POlHL-1 131012 0073 Mechanisms of cardiovascular
disease - Electrophysiological study of atrial fibrillation
(human)
' P01HL11310-12 0074 Mechanisms of cardiovascular
disease - Electrophysiological studies of paraxysmal atrial
tachycardia (human)
' POlHL-11310-12 0076 Mechanisms of cardiovascular
disease - Tratment of depressed cardiac output following
heart surgery (children, puppies)
' POlHL-11310-12 0077 Mechanisms of cardiovascular
disease - Abnormalities of rhythm and conduction following
heart surgery (human)
POlHL-11310'12 0081 Mechanisms of cardiovascular
disease • Analysis of regional left ventricular function
(human)
POlHL-1 1310-12 0082 Mechanisms of cardiovascular
disease - Myocardial function in adult congenital heart
disease (human)
POlHL-11310-12 0083 Mechanisms of cardiovascular
disease ■ Ventricular volume and hemodynamics in adult
congenital heart disease
POlHL-l 1310-12 0093 Mechanisms of cardiovascular
disease - Multiple dipole electrocardiogram project (human,
dogs)
POlHL-1 1310-12 0095 Mechanisms of cardiovascular
disease ■ Blood and transfusion disorders (human, rats,
monkeys)
P01HL11310-12 9001 Mechanisms of cardiovascular
disease - Core support-hospital beds
ROlHL-1 1919-08 Pulmonary circulation in surgical heart
disease (human, dogs)
POlHL-12373-10 0003 Cardiopulmonary physiology and
pathophysiology - Myocardial function in man
ROlHL-12542-07 Natural history, congenital heart defects-
Joint study (human)
POlHL-12738-10 0071 Physiologic pharmacology and Its
clinical applications ■ lABP patient management in
ventricular power failure (human)
POlHL-12738-10 0092 Physiologic pharmacology and its
clinical apphcatlons - Subendocardial ischemia following
open heart surgery (human)
P01HL12738-10 0094 Physiologic pharmacology and its
clinical applications - Ventricular function and structure
(human, dogs)
POlHL-1273810 0123 Physiologic pharmacology and its
clinical applications - Ventricular assistance and
preservation (human, dogs)
POlHL-12738-10 0127 Physiologic pharmacology and its
clinical applications - Cardiac electrical activity (human,
animals)
POlHL-12738-10 0128 Physiologic pharmacology and its
clinical applications - Recording electrograms from
specialized cardiac tissues (human, dogs)
POlHL-12738-10 0130 Physiologic pharmacology and its
clinical applications - Compatibility enhancement during
cardiac allografting (dogs)
POlHL-12738-10 0131 Physiologic pharmacology and its
clinical applications - Evaluation of intracardiac shunts by
contrast echocardiography (dogs)
P01HL12738-10 0133 Physiologic pharmacology and its
clinical applications - Pharmacologic antagonism of beta-
adrenergic blockade (dogs)
POlHL-13108-09 Clinical heart transplantation
POIHL13108-09 0001 Clinical heart transplantation ■
Therapy and prognosis (human)
POlHL-1310809 0002 Clinical heart transplantation -
Preoperative immunologic studies of cardiac recipients
POlHL-l 3 108-09 0003 Clinical heart transplantation -
Endomyocardial biopsy pathology
P01HL13108-09 0009 Clinical heart transplantation - B
cell alloantigens in cardiac allograft compatibility (human)
POlHL-13108-09 0010 Clinical heart transplantation -
Serum factors Inhibiting lymphocyte responses in MLC
(human, bush babies)
274
POlHL-13108-09 0011 Clinical heart transplantation -
Humoral and cellular kinetics of allograft rejection (human)
POlHL-13108-09 0012 Clinical heart transplantation -
Human T cell sheep erythrocyte receptors
P01HL13108-09 0013 Clinical heart transplantation -
Cardiomyopathic lymphocyte responsiveness to cultured
endothelium
P01HL13 108-09 0014 Clinical heart transplantation -
Platelets and coagulation in accelerated graft coronary
atherosclerosis
POlHL-13108-09 0015 Clinical heart transplantation -
Antithymocyte globulin analysis and clinical effects
POlHL-13108-09 0016 Clinical heart transplantation -
Total lymphoid irradiation for immune response (dogs)
P01HL13 108-09 0017 Clinical heart transplantation ■
Electrophysiology of the transplanted denervated human
heart
POlHL-1310809 0018 Clinical heart transplantation -
Electrophysiologic studies of cardiac drugs in the
denervated heart
POlHL-131 08-09 0019 Clinical heart transplantation -
Effect of autonomic nervous system on arrhythmias
(human)
POlHL-13 108-09 0020 Clinical heart transplantation
Autonomic neural studies in the denervated heart (human)
POlHL-l 3 108-09 0021 Clinical heart transplantation -
Autonomic reflex regulation of ventricular function (human)
POlHL-131 08-09 0022 Clinical heart transplantation -
Studies on cardiac receptors (human)
POlHL-13737-07 0033 Assisted circulation - Autologous
bioprosthetic grafts for coronary artery bypass surgery
(human, dogs)
POlHL-13737-07 0037 Assisted circulation - Clinical
measurement of blood flow through aorto-coronary vein
bypass graft
POlHL-13737-07 0038 Assisted circulation
Distinguishing the ischemic ventricle from scarred ventricle
by balloon pumping
P01HI.-13738-08 0002 Cardiac assist devices and
artificial hearts - Total replacement with artificial heart
(calves, sheep, ponies)
POlHL-13738-08 0003 Cardiac assist devices and
artificial hearts - Pathophysiological effects of the artificial
heart (calves)
ROlHL-13920-07 Expanding the role of surgery of atrial
dysrhythmias (dogs)
ROlHL-147 13-06 Hypothermia and the heart (bats, guinea
pigs)
R01HI.-15190-07 Physiological basis of arrhythmias and
their therapy (human)
POlHl-l 51 94-07 0019 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation, bypass
grafts and diastolic driving pressure (human, dogs)
ROlHL-16292-05 0002 Surgery and non-obstructive
coronary insufficiency - Effects of hypothermia during
cardiopulmonary bypass (dogs)
ROlHL-16329-04 Cardiac surgical effect on heart function
In infants (human)
ROlHL-164 12-04 Release of nucleosides from the ischemic
heart (human, dogs)
P60HL- 172 92-04 0029 Vermont Lung Center - Computer-
assisted pre-operative evaluation (human)
ROlHL-17578-04 Exercise performance In children with
heart disease
P50HL-17667-04 0022 Study of ischemic heart disease -
Preventing myocardial injury in surgery using
cardiopulmonary bypass (human, rat)
P50HL-17667-04 0029 Study of ischemic heart disease -
Computer diagnosis of cardiac arrhythmias after open
heart surgery (human)
P50HL-17670-04 0008 Study of ischemic heart disease -
Surgical treatment of cardiac rhythm disorders (human,
dogs)
P50HL-17670-04 0009 Study of ischemic heart disease -
Surgical treatment of localized left ventricular dyssynergy
(human, dogs)
ROlHL-17993-04 Ventricular dynamics from surgically
inserted markers
ROlHL-1 7993-04 0001 Ventricular dynamics from
surgically inserted markers - Effects of aortocoronary
bypass graft surgery on ventricular function (human)
ROlHL-17993-04 0003 Ventricular dynamics from
surgically inserted markers - Effects of pharmacologic
agents on left ventricular dynamics (human)
ROlHL-17993-04 0005 Ventricular dynamics from
surgically inserted markers - Cardiac dimensions and
dynamic after mitral, aortic valve surgery (human)
ROlHL-17993-04 0009 Ventricular dynamics from
surgically inserted markers - Cardiovascular visualization In
surgeiy of growing heart (dogs)
ROlHL-17993-04 0010 Ventricular dynamics from
surgically inserted markers - Postoperative cardiovascular
visualization (human)
ROlHL-18288-04 Intraoperative protection of the
myocardium (dogs, rats)
ROlHL-18398-04 Mechanisms of delayed and asymetric
ventricular conduction (human, dogs)
ROlHL-185 17-03 Intrinsic innervation of the heart (dogs)
POlHL-18646-03 0004 Studies basic to heart
transplantation - Presensitization -Detection, incidence and
clinical significance
HEA
ROIHL- 19089-03 Diastolic properties of the left ventricle
(human, dogs)
ROlHL-1918203 Surgical aspects of myocardial
hypertrophy (dogs)
ROlHL-19203-03 Surgical approach to congenital heart
diseases (dogs, primates)
ROlHL-19246-03 Regression of cardiac hypertrophy-
Myocardlal and renal (human)
ROlHL-19414-03 Protection of myocardium during cardiac
surgery (dogs, cats, human)
ROlHL-19451-03 Functional characteristics of the left
heart
ROlHL-19451-03 0001 Functional characteristics of the
left heart - Ventricular performance using epicardial
radiopaque markers (human)
R01HL19451-03 0003 Functional characteristics of the
left heart - Left ventricular segmental contraction (human,
dogs)
ROlHL-20080-02 Surgically induced myocardial edema
(dogs)
ROlHL-20143-02 Hypothermic circulatory arrest-Cerebral
vascular change (dogs)
POlHL-20552-02 The development and regression of
cardiac hypertrophy
ROIHL 20630-03 Development of a pulsed Doppler velocity
detector (human, animals)
ROlHL-20720-02 Myocardial protection during
cardiopulmonary bypass (dogs)
ROlHL-20803-02 Intra-aortic balloon pumping (dogs,
lambs, cats)
Cineangiographic studies of
Densitometry in coronary stenosis
ROlHL-20895-03 0003
cardiovascular system
(human)
ROlHL-20895-03 0011
cardiovascular system
Cineangiographic studies of
Ventricular hypertrophy and
preoutflow contraction (human, dogs)
ROlHL-21210-01 Acute renal failure following cardiac
surgery (human)
R23HL-21292-01 Human ventricular activation-Patterns
and mechanisms (human)
ROlHL-21293-02
surgery (human)
R23HL-21347-02
tachycardia
ROlHL-22098-01
Randomized study of coronary bypass
Accessory pathways and supraventricular
*Eadudn routine methodotogy OR coven only general projects which preclude Indexing at the specific level.
* 'SiitiiM :l°nifiuntly to above ubjact.
Is postoperative Infarction due to
reperfusion injury? (human, dogs)
** ROlHL-22 152-02 Ventricular dysfunction and cardiac
surgery (dogs)
ROlHL-22759-01 Regional myocardial blood flow during
hypothermia (dogs)
R23HL-22787-01 Cardiac volume by biplane
echocardiography (human)
** ROlHL-22894-01 Two dimensional ultrasound and cardiac
surgery (human, dogs)
HEART SURGERY, PERICARDIOTOMY
SEE ALSO DISEASES, COMPLICATIONS, POSTPERICARDIOTOMY
SYNDROME
ROlHL-16246-06 Immunologic studies In
postpericardiotomy syndrome (human)
ROlHL-22894-01 Two dimensional ultrasound and cardiac
surgery (human, dogs)
HEART SURGERY, SEPTAL DEFECT THERAPEUTIC
POlHL-11310-12 0061 Mechanisms of cardiovascular
disease - Computer simulation of transposition of great
arteries in infants
POlHL-1273810 0076 Physiologic pharmacology and its
clinical applications - Pediatric cardiac electrophysiology
and pharmacology (human, dogs)
HEART TRANSPLANTATION
SEE ALSO HEART PRESERVATION
M POlHL-06312-17 Surgical cardiology
*♦ POlHL-06312-17 0017 Surgical cardiology - Cardiac
transplantation (human)
** POlHL-06312-17 0018 Surgical cardiology - Cardiac
transplantation growth (calves)
** POlHL-06312-17 0021 Surgical cardiology - Cardiac
transplantation-Effect of immunosuppression on
atherogenesis (monkeys)
** POlHL-06312-17 0022 Surgical cardiology - Cardiac
transplant-Experimental simultaneous heart and kidney
transplant (dogs)
** POlHL-06312-17 0023 Surgical cardiology ■ Effect of
denervation on atherosclerosis
** POlHL-06312-17 0028 Surgical cardiology - Coronary flow
in the transplanted denervated heart (dogs)
** POlHL-06312-17 0029 Surgical cardiology - Cardiac
lymphatics in the transplanted heart (dogs)
** POlHL-06312-17 0032 Surgical cardiology ■ Preservation
of the heart by perfusion (dogs)
** POlHL-06312-17 0039 Surgical cardiology - Cardiac
transplantation-Biopsy correlates of rejection
** POlHL-06312-17 0040 Surgical cardiology - Left ventricle
assist (dogs)
POlHL-06370-17 0001 Cardiopulmonary and renal
pathology research center ■ The humoral and cellular
mechanisms of allograft rejection (monkeys)
M ROlHL-08696-15 Orthotopic heart transplantation
** ROlHL-08696-15 0001 Orthotopic heart transplantation -
Transplantation immunology-Antithymocyte globulin
(rabbits, monkeys)
(contd)
M Grant has subpnijects describing specific researeh aspects.
See Appendix for Investigator's name and grant number.
HEA
ROIHL 08696 lb 0004 Orthotopic liearl timisplanlation
Transplantation immunology Avian antibody studies
(chickens, rats, rabbits)
R01H108696 15 0010 Orthotopic heart ttansplanlation
Ttansplantation immunology Total lymphoid iiiadiation
(dogs, primates)
' R01HL08696 IS 0011 Orthotopic heart transplantation
Transplantation immunology -Immunodepressive factor
(human, dogs)
' R01H108696 15 0012 Orthotopic heart transplantation
Transplantation immunology Modulation ol donor
antigenicity (dogs)
' ROIHI 08696 15 0013 Orthotopic heart transplantation
Transplantation immunology Cardiac heterotransplantation
(rabbits, dogs)
' R01HL08696 15 0014 Orthotopic heart transplantation
Transplantation immunology- Cardiac relransplantation
(dogs)
* ROIHL'08696'IS 0018 Orthotopic heart transplantation ■
Training in cardiac transplantation
* R01HL08696 15 0019 Orthotopic heart transplantation
Suppressor cell stimulation (dogs, mice)
* R01HL08696-15 0020 Orthotopic heart transplantation
Complete cardiopulmonary transplantation (dogs)
* P01HL1273810 0130 Physiologic pharmacology and its
clinical applications Compatibility enhancement during
cardiac allografting (dogs)
I P01HL1310809 Clinical heart transplantation
* POIHL 13108-09 0001 Clinical heart transplantation ■
Therapy and prognosis (human)
* POlHL-13108-09 0002 Clinical heart transplantation ■
Preoperative immunologic studies of cardiac recipients
* POIHL 13108-09 0003 Clinical heart transplantation •
Endomyocardial biopsy pathology
* POlHL-1310809 0008 Clinical heart transplantation ■
Physiology and pharmacology of the transplanted human
heart
'* POIHL 13108 09 0009 Clinical heart transplantation B
cell alloantigens in cardiac allograft compatibility (human)
'* POlHL-13108-09 0010 Clinical heart transplantation
Scrum factors inhibiting lymphocyte responses in MLC
(human, bush babies)
'* POlHL-13108-09 0011 Clinical heart transplantation -
Humoral and cellular kinetics of allograft rejection (human)
'* POlHL-13108-09 0012 Clinical heart transplantation ■
Human T cell sheep erythrocyte receptors
" P01HL13108-09 0013 Clinical heart transplantation -
Cardiomyopathic lymphocyte responsiveness to cultured
endothelium
•* P01HL13108-09 0014 Clinical heart transplantation -
Platelets and coagulation in accelerated graft coronary
atherosclerosis
** POlHL-13108-09 0015 Clinical heart transplantation -
Antithymocyte globulin analysis and clinical effects
** POlHL-13108-09 0016 Clinical heart transplantation -
Total lymphoid irradiation for immune response (dogs)
** POlHL-13108-09 0017 Clinical heart transplantation ■
Electrophysiology of the transplanted denervated human
heart
** POlHL-1310809 0018 Clinical heart transplantation
Electrophysiologic studies of cardiac drugs in the
denervated heart
** P01HL13108-09 0019 Clinical heart transplantation -
Effect of autonomic nervous system on arrhythmias
(human)
** POlHL-13108-09 0020 Clinical heart transplantation -
Autonomic neural studies in the denervated heart (human)
** POlHL-13108-09 0021 Clinical heart transplantation -
Autonomic reflex regulation of ventricular function (human)
** POlHL-13108-09 0022 Clinical heart transplantation •
Studies on cardiac receptors (human)
** POlHL-13108-09 0023 Clinical heart transplantation -
Adaptive mechanisms of the denervated heart (human)
** POlHL-13108-09 0024 Clinical heart transplantation ■
Response of denervated heart to stress-Noninvasive
(human)
POlHL-13737-07 0024 Assisted circulation - Dynamic
prosthetic myocardium (dogs)
** ROlHL-14799-07 Cardiac heterotransplantation-
Immunologic modification (mice, rat)
** P60HL-1 7269-04 0034 National heart and blood vessel
research and demonstration center - Immunologic
enhancement of cardiac allografts (mice)
ROIHL- 1 7902-04 Mammalian renal microcirculation
(hamsters)
** ROlHL-17993-04 0002 Ventricular dynamics from
surgically inserted markers - Left ventricle function in
human cardiac allograft
** R01HL-17993-C4 0006 Ventricular dynamics from
surgically inserted markers - Atrial pacing in transplant
patients
** ROlHL-18186-04 Cardiac allografts in autologous
radiation chimeras (rats, dogs)
ROlHL-18517-03 Intrinsic innervation of the heart (dogs)
M P01HL18646-03 Studies basic to heart transplantation
" POlHL-18646-03 0001 Studies basic to heart
transplantation - Individualized regulation of
immunosuppression (dogs, rats)
** POlHL-18646-03 0002 Studies basic to heart
transplantation - Detection of rejection (dogs)
275
** POIHL 18646 03 0003 Studies basic to heart
transplantation Host responses to aenogratts (lodenls.
rabbits)
*• POIHL 18646 03 0004 Studies basic to heart
transplantation Presensili/ation Detection, incidence and
clinical significance
POIHL 18646 03 0006 Studies basic to heart
transplantation Reduction or elimination of existing
presensitization (human, animals)
** POIHL 18646 03 0008 Studies basic to heart
transplantation Immunophysiology and early detection of
rejection (dogs)
** POlHL-18646 03 0009 Studies basic to heart
transplantation Pathologic aspects of cardiac allograft
reiection (sheep, dogs)
•* POIHL 18646-03 0010 Studies basic to heart
transplantation Development and study of a heart
preservation chamber (dogs, sheep)
•* ROIHL 18936-02 Heart preservation and transplantation
studies (rat)
ROIHL 20356 02 Development and evaluation of an
artificial heart (calves)
" R23HL 22448-01 Modulation of heart graft antigenicity by
pertusion (rats)
HEART TRANSPLANTATION, VAIVES
TRANSPLANTATION
P01HL06370 17 0014 Cardiopulmonary and renal
pathology research center - Quantitative morphology in
cardiac disease (human, rats, dogs)
POlHL-11310-12 0057 Mechanisms of cardiovascular
disease - Blood pressure reduction after heart surgery in
adults (human)
POlHL-1 13 10-12 0081 Mechanisms of cardiovascular
disease Analysis of regional left ventricular function
(human)
POlHL-12373-10 0003 Cardiopulmonary physiology and
pathophysiology - Myocardial function in man
POlHL-1273810 0092 Physiologic pharmacology and its
clinical applications Subendocardial ischemia following
open heart surgery (human)
ROlHL-16461-05 Late results of valve replacement -
Computer analysis (human)
** P50HL-1 7665-04 0020 Study of ischemic heart disease -
Ischemic injury to myocardium during measured states of
ischemia (human)
P50HL-17665-04 0028 Study of ischemic heart disease
Pathologic and biochemical studies of ischemic
myocardium (human, dog)
P50HL 17667-04 0022 Study of ischemic heart disease
Preventing myocardial injury in surgery using
cardiopulmonary bypass (human, rat)
ROlHL-17993-04 0001 Ventricular dynamics from
surgically inserted markers • Effects of aortocoronary
bypass graft surgery on ventricular function (human)
ROlHL-1799304 0002 Ventricular dynamics from
surgically inserted markers - Left ventricle function in
human cardiac allograft
ROlHL-17993-04 0003 Ventricular dynamics from
surgically inserted markers • Effects of pharmacologic
agents on left ventricular dynamics (human)
** ROlHL-17993-04 0005 Ventricular dynamics from
surgically inserted markers • Cardiac dimensions and
dynamic after mitral, aortic valve surgery (human)
R01HL19203-03 Surgical approach to congenital heart
diseases (dogs, primates)
ROlHL-1924603 Regression of cardiac hypertrophy-
Myocardial and renal (human)
** ROlHL-198 18-02 Endocarditis on prosthetic heart valves
(rabbits, human)
R01HL-20037-02 Left ventricular-aortic bypass and
composite prosthesis (sheep, swine, cattle)
** ROlHL-20829-02 Fluid mechanics of heart valve
prostheses (dogs, human)
ROlHL-22888-01 Prosthetic valve endocarditis-Etiology
and therapy (dogs)
NOlHV-72939-01 Develop and evaluate left heart assist
blood pumps (human, calves, pigs)
HEART VALVES
SEE HEART. VALVES
HEART VALVES PROSTHETIC
SEE HEART PROSTHESIS. VALVES PROSTHETIC
HEART VALVES TRANSPLANTATION
SEE HEART TRANSPLANTATION. VALVES TRANSPLAI*ITATION
HEART VALVULAR DISORDERS
SEE HEART DISORDERS. VALVULAR
HEART VESSELS
Regulation of the circulation in
Adrenergic receptors in coronary
POlHL-14388-07 0163
pathological states
vessels (dogs)
POlHL-14388-07 0220
pathological states
circulation in man
R01HL18639-03 Human anatomy for cardiac prostheses
(human)
ROlHL-20787-02 Thromboxanes and prostaglandins -
Biochemical pharmacology (rabbits, human)
Regulation of the circulation in
Pharmacology of the coronary
HEA
HEART VESSELS, CORONARY ARTERIES
ROIHI 01803 ?1 0010 ArltTiO'.r.lcioir.. glomerulonephnti-.,
rheumatic fever Athero%cl«rosis induction Graft rejection
and hypercholesterolemia (rabbits)
ROIHL 0180373 0011 Arterioscleiosii, glomerulonephriln.
rheumatic fever Immunopathologic consequpncei ol
cigarette smoking (human, rabbits, plants)
ROIHL 01803 23 0014 Arteiiosclcro',!',. glomerulonephritu,
rheumatic fever Regenerated endothelium on lipid
accumulation in arterial wall (rabbit)
** POIHL 06285 18 0131 Cardiovascular respiratory
physiology and biochemistry fetal heart development and
ventricular outflow obstruction (lambs)
P01HL06285 18 0143 Cardiovascular respiratory
physiology and biochemistry Myocardial ischemia (human.
dogs, lambs)
POlHL-06285-18 0156 Cardiovascular-respiratory
physiology and biochemistry Myocardial performance
following revascularization (human)
P01HL06312 17 0028 Surgical cardiology Coronary flow
in the transplanted denervated heart (dogs)
" ROIHL 08659 14 Myocardial performance and metabolism
in the newborn (sheep)
POIHL 08682 15 0005 Regulation of the cardiovascular
system Smooth muscle and mechanical properties of
blood vessels (dogs, human)
POIHL 08682 15 0011 Regulation of the cardiovascular
system Histochemistry and ultrastructure of heart
innervation (dogs, ground squirrels)
" P01HL11310 12 0090 Mechanisms of cardiovascular
disease Clinicopathological cardiovascular correlation
(human, animals)
POlHL-11310 12 9001 Mechanisms of cardiovascular
disease - Core support-hospital beds
** POlHL-11414-11 0024 Thrombosis and atherosclerosis
program Radiographic demonstration of small coronary
arteries (human, dogs)
ROlHL-12083-11 Flow field in aorta and its major
branches (dogs, phantom models)
** P50HL-14164-07 0044 A/S SCOR- Comparative and
experimental atherosclerosis ■ Cell biology-atherosclerosis
project (pigeons)
P50HL-14236-05 0007 Prevention of premature
arteriosclerosis - Exercise stress testing
hyperlipoproteinemia (human)
** POlHL-14388-07 0162 Regulation of the circulation in
pathological states - Phasic coronary flow and myocardial
perfusion in aortic regurgitation (dogs)
** ROlHL-16236-04 Detailed characteristics of coronary blood
flow (horses, dogs, calves)
ROlHL-16587-04 Cholesterol binding saponins and
atherosclerosis (monkeys)
** R01HL16657-06 Innervation of coronary arteries and heart
(rats)
P60HL- 17269-04 0026 National heart and blood vessel
research and demonstration center - Dynamics of ischemic
heart disease (human, dog)
P50HL-17648-04 0006 Study of ischemic heart disease -
Ventricular performance and myocardial perfusion in
obstructive coronary disease
P50HL-17648-04 0012 Study of ischemic heart disease -
Retrograde coronary venous perfusion -Acute myocardial
ischemia
P50HL-1 7648-04 0013 Study of ischemic heart disease -
Fate of bypassed and bypassing vessels (dogs)
P50HL-17648-04 0021 Study of ischemic heart disease -
Biventricular contractile responses to acute myocardial
infarction (mammals)
P50HL-1765104 0037 Ischemic heart disease specialized
center of research - Measurement of coronary venous
outflow by thermodilution (human)
** P50HL-17655-04 0004 Study of ischemic heart disease -
Coronary arteriography in survivors of acute myocardial
infarction (human)
P50HL-17655-04 0006 Study of ischemic heart disease •
Evaluation of coronary artery bypass graft surgery (human)
P50HL-17655-04 0009 Study of ischemic heart disease -
Random trial of medical and surgical therapy in unstable
angina (human)
P50HL-17665-04 0012 Study of ischemic heart disease -
Myocardial ischemia-Cardiovascular performance in the
conscious baboon and dog
P50HL-17665-04 0013 Study of ischemic heart disease -
National cooperative study in unstable angina pectoris
(human)
P50HL-17665-04 0021 Study of ischemic heart disease -
Identification, prevention-Myocardial ischemia in
cardiopulmonary bypass (dog)
P50HL- 17669-04 0008 Ischemic heart disease center
(SCOR) - Segmental ventricular dysfunction during stress-
induced ischemia (dog, human)
P50HL-17670-04 0006 Study of ischemic heart disease -
Assessment of coronary artery hemodynamics and
myocardial blood flow (human)
P50HL-17682-04 0005 Study of ischemic heart disease -
Regional myocardial perfusion deficits and segmental
contraction disorders in man
P50HL-1 7682-04 0013 Study of ischemic heart disease -
Chronic ischemic heart disease- Myocardial function and
metabolism (dogs, swine)
(contd)
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
HEA
P50HL-17682-04 0021 Study of ischemic heart disease -
Prostaglandin biosynthesis in blood vessels from ischemic
myocardium (rath sheep)
P01HL18208-04 0006 Center for the study of blood cell
rheology - Analysis of flow in arterioles and capillaries
(human)
ROlHL-18441-03 Guidelines for polymers acting as elastin
substitutes
R01HL18468-03 The distribution of flow in the
myocardium {dog, pig)
ROlHL-18599-02 Cardiovascular pharmacology of
ionophores (dogs)
ROlHL-18793-03 Clinical-pathologic studies of sudden
cardiac death (human)
ROlHL-20163-02 Competitive coronary flow in native and
graft vessels (dog)
ROlHL-2019602 Regulation of coronary arterial smooth
muscle
ROlHL-20226-02
physiology (dogs)
ROlHL-20426-03
(dog, rat)
ROlHL-20428-03
ROlHL-20678-02
Cardiac bypass and coronary collateral
Myocardial function in diabetes mellitus
Total synthesis of natural cardiotonic
Analysis of coronary artery behavior
Collaborative studies on coronary artery
Collaborative studies on coronary artery
The juvenile diabetic heart (human)
Cardiovascular adaptation to stress in
disease states (dogs)
R01HL-2078702 Thromboxanes and prostaglandins-
Biochemical pharmacology (rabbits, human)
ROlHL-20829-02 Fluid mechanics of heart valve
prostheses (dogs, human)
** R01HL-2I187-01 Potassium, norepinephrine, and coronary
arterial tone (dogs)
R23HL-21298-02 Coronary vasomotion (dogs, pigs)
ROlHL-22739-01 Evolution and progression of pediatric
atherosclerosis
R01HL-22778-01
ionophores
" R01HL-22801-01
(dogs)
" ROlHL-22952-01 Validation of quantitative coronary
arteriography (dogs)
ROlHL-23171-01 Coronary collateral circulation in
myocardial ischemia (dog, pig, rat, human)
** NOlHV-32973-12 Coordinating center for collaborative
studies on coronary artery surgery
" NOlHV-32978-08
surgery
'* NOlHV-32979-09
surgery
NOlHV-72924-04 Non-invasive detection of atherosclerotic
lesions (human, animals)
NOlHV-72929-01 Improved detection of atherosclerosis
(human, dogs)
NOlHV-72930-02 Atherosclerosis assessment-Angiography
and ultrasound (dogs, human)
NOlHV-72931-02 Non-invasive detection of atherosclerotic
lesions (human, dogs)
NOlHV-72932-00 Non-invasive detection of atherosclerotic
lesions (human, phantoms)
HEART VESSELS, CORONARY VEINS
POlHL-08682-15 0011 Regulation of the cardiovascular
system - Histochemistry and ultrastructure of heart
innervation (dogs, ground squirrels)
** POlHL-15194-07 0001 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation, venous
drainage and collateral flow (human, dogs)
** POlHL-15194-07 0017 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation and
effects of artcriographic lesions on flow (human)
POlHL-15194-07 0018 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation,
metabolic demand and vasodilatory reserve (human, dogs)
** P50HL-17648-04 0012 Study of ischemic heart disease -
Retrograde coronary venous perfusion-Acute myocardial
ischemia
P50HL-1 7648-04 0013 Study of ischemic heart disease -
Fate of bypassed and bypassing vessels (dogs)
P50HL-17651-04 0016 Ischemic heart disease specialized
center of research - Retroperfusion of coronary venus
circulation with therapeutic agents (dogs)
** P50HL-17651-04 0037 Ischemic heart disease specialized
center of research - Measurement of coronary venous
outflow by thermodilution (human)
P50HLI768204 0021 Study of ischemic heart disease -
Prostaglandin biosynthesis in blood vessels from ischemic
myocardium (rat, sheep)
ROlHL-20163-02 Competitive coronary flow in native and
graft vessels (dog)
HEART VESSELS, CORONARY VEINS,
CORONARY SINUS
POlHL-1 1310-12 0068 Mechanisms of cardiovascular
disease - Pharmacological intervention and myocarcial
oxygen consuption (human, dogs)
POIHL 12738-10 0080 Physiologic pharmacology and its
clinical applications - Electrophysiology of cardiac muscle
in the mitral valve (monkeys)
POlHL-14388-07 0220 Regulation of the circulation in
pathological states - Pharmacology of the coronary
circulation in man
POlHL-15194-07 0018 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation,
metabolic demand and vasodilatory reserve (human, dogs)
276
ROlHL-164 12-04 Release of nucleosides from the ischemic
heart (human, dogs)
P50HL-17651-04 0032 Ischemic heart disease specialized
center of research - Cardiovascular surgery core (human,
dogs)
P50HL-176S1-04 0037 Ischemic heart disease specialized
center of research - Measurement of coronary venous
outflow by thermodilution (human)
P50HL-17e65-04 0021 Study of ischemic heart disease -
identification, prevention -Myocardial ischemia in
cardiopulmonary bypass (dog)
HEART VISUALIZATION*
SEE ALSO CARDIOVASCULAR VISUALIZATION*
SEE ALSO HEART DISORDERS DIAGNOSIS (INCL EXAMS)*
** P50HL-17655-04 0012 Study of ischemic heart disease -
DATA management
** ROlHL-21846-01 Cardiac failure detection by radiography
and optics (monkeys)
HEART VISUALIZATION,
ANGIOCARDIOGRAPHY*
** POIHL 11414-11 0024 Thrombosis and atherosclerosis
program - Radiographic demonstration of small coronary
arteries (human, dogs)
** ROlHL-16484-04 Radiographic ventrlculometry for coronary
heart disease (human)
R01HL-20e74-02 Evaluation of cardiac function with
radioactive tracers
ROlHL-20677-02 Radionuclide studies in congenital heart
disease
ROlHL-20895-03 0001 Cineangiographic studies of
cardiovascular system - Videodensitometry and valvular
regurgitation (human, dogs)
ROlHL-21273-02 Fibrinogen labeling with radiometals
R23HL-21279-02 Angiographic estimation of
atherosclerotic wall thickness
ROlHL-21589-01 Radiographic contrast toxicity in
ischemic heart
** ROlHL-2 17 93-02 Functional infarct size by gated
radioangiography (human, dogs)
ROlHL-23983-01 Quantitative radiocardiography (human,
dogs)
HEART VISUALIZATION,
ANGIOCARDIOULTRASONOGRAPHY*
POlHL-04664-18 0010 Cardiovascular and lung dynamics
Left ventricular dynamics (human)
POlHL-04664-18 0012 Cardiovascular and lung dynamics
- Quantitative single plane left ventricular angiography
(human)
M POlHL-07293-17 Non-invasive cardiovascular
measurements
** POlHL-07293-17 0041 Non-invasive cardiovascular
measurements - Ventricular volumes and dimensions
(human)
** POlHL-07293-17 0042 Non-invasive cardiovascular
measurements - Ventricular imaging software (human)
** POlHL-07293-17 0043 Non-invasive cardiovascular
measurements - ECHO-Doppler instrumentation for cardiac
measurements (human)
** POlHL-07293-17 0044 Non-invasive cardiovascular
measurements - Cardiac duplex scanner
** POlHL-07293-17 0045 Non-invasive cardiovascular
measurements - Cardiac scanner transducer position
locating systems (human)
** POlHL-07293-17 0046 Non-invasive cardiovascular
measurements - Cardiac scanner signal processors
** POlHL-07293-17 0047 Non-invasive cardiovascular
measurements - Cardiac scanner system software
** POlHL-07293-17 0048 Non-invasive cardiovascular
measurements - Cardiac scanner recording and display
systems component
** POlHL-07293-17 0049 Non-invasive cardiovascular
measurements - Cardiac scanner engineering evaluation
and error analysis
** POlHL-07293-17 0050 Non-invasive cardiovascular
measurements - Cardiac dimensions measurements
engineering evaluation and error analysis
** POlHL-07293-17 0051 Non-invasive cardiovascular
measurements - Physiologic evaluation of duplex scanner
(dogs)
** POlHL-07293-17 0052 Non-invasive cardiovascular
measurements - Clinical evaluation of the duplex scanner
(human)
** POlHL-07293-17 0053 Non-invasive cardiovascular
measurements - Clinical evaluation of cardiac dimensions
using the duplex scanner (human)
** POlHL-07293-17 0054 Non-invasive cardiovascular
measurements - Detection of arterial occlusive disease
(human)
** POlHL-07293-17 0055 Non-invasive cardiovascular
measurements - Peripheral vascular transducer position
locating system
** POlHL-07293-17 0056 Non-invasive cardiovascular
measurements - Peripheral vascular system software
** POlHL-07293-17 0057 Non-invasive cardiovascular
measurements - Peripheral vascular scanner engineering
evaluation and error analysis (human)
** POlHL-07293-17 0058 Non-invasive cardiovascular
measurements - Peripheral duplex scanner physiologic
evaluation
HEA
** POlHL-07293-17 0059 Non-invasive cardiovascular
measurements - Intracardiac blood flow measurement
(human)
POlHL-12373-10 0005 Cardiopulmonary physiology and
pathophysiology - Characterization of fetal and neonatal
myocardium (human, cats)
** ROlHL-12715-10 Dynamic cardiovascular measurement
using ultrasound
ROlHL-14785-07 Ultrasonic scattering for tissue
characterization (dogs, cattle, human)
ROlHL-14903-07 A new index of cardiac contractility
(human, dogs, baboons)
** ROIHL- 16260-04
cardiography
ROlHL-16487-05
Development of clinical cine ultrasound
Computer controlled two dimensional
Preprocessor system for cardiograms
Ultrasonic monitoring visceral blood
echocardiography
** ROlHL-18144-03
(human)
ROlHL-19791-02
vessels
ROlHL-20898-02 Ultrasonic evaluation in direct arterial
surgery (models, cattle, human)
** NOlHV-52966-01 Development and evaluation of an
ultrasonic imaging system (swine)
** NOlHV-7292700 Systems for non-invasive detection of
atherosclerotic lesions (human)
*• NOlHV-72928-04 Develop high resolution ultrasonic
imaging techniques
** NOlHV-72930-02 Atherosclerosis assessment-Angiography
and ultrasound (dogs, human)
HEART VISUAUZATION,
CINEANGIOCARDIOGRAPHY*
M P01HL-04e64-18 Cardiovascular and lung dynamics
** POlHL-12373-10 0003 Cardiopulmonary physiology and
pathophysiology - Myocardial function in man
** POlHL-12373-10 0015 Cardiopulmonary physiology and
pathophysiology - Cine angiographic-hemodynamic facility
P50HL-14192-08 0008 Specialized center of research in
hypertension - New radiographic methods-Recognition of
renovascular hypertension (human, dog)
ROlHL-15512-06 Drug treatment of stenosing primate
atherosclerosis (rabbits, monkeys)
** ROIHL 16260-04 Development of clinical cine ultrasound
cardiography
P60HL-17269-04 0026 National heart and blood vessel
research and demonstration center - Dynamics of ischemic
heart disease (human, dog)
** ROlHL-17532-04 Infarct size-ECG, angio, path, correlation
in dogs
P50HL-17648-04 0034 Study of ischemic heart disease -
Data management -Hemodynamic data
M ROlHL-17993-04 Ventricular dynamics from surgically
inserted markers
ROlHL-17993-04 0001 Ventricular dynamics from
surgically inserted markers - Effects of aortocoronary
bypass graft surgery on ventricular function (human)
ROlHL-17993-04 0002 Ventricular dynamics from
surgically inserted markers - Left ventricle function in
human cardiac allograft
** ROIHL- 17993-04 0009 Ventricular dynamics from
surgically inserted markers - Cardiovascular visualization in
surgery of growing heart (dogs)
** ROlHL-17993-04 0010 Ventricular dynamics from
surgically inserted markers - Postoperative cardiovascular
visualization (human)
ROlHL-18683-03 Left ventricle function in aortic
regurgitation (human)
** ROlHL-19003-03 High precision densitometry of coronary
angiograms
M ROlHL-19451-03 Functional characteristics of the left
heart
** ROlHL-19451-03 0001 Functional characteristics of the
left heart - Ventricular performance using epicardial
radiopaque markers (human)
** ROlHL-19451-03 0003 Functional characteristics of the
left heart - Left ventricular segmental contraction (human,
dogs)
** ROlHL-19451-03 0004 Functional characteristics of the
left heart - Quantitative coronary arteriography (human)
ROlHL-20895-03 0003 Cineangiographic studies of
cardiovascular system - Densitometry in coronary stenosis
(human)
ROlHL-20895-03 0004
cardiovascular system
*Excludes routine methodotogy OR covers only general projects which preclude indexing at the specific level.
**Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
Cineangiographic studies of
Cineangiography-Coronary lesions
and ventricular function (human)
** R23HL-21 197-02 Right ventricular contraction and
relaxation (dogs)
ROlHL-21985-01 Videoroentgenography in congenital heart
disease
HEART VISUALIZATION, ECHOCARDIOGRAPHY*
POlHL-06285-18 0155 Cardiovascular-respiratory
physiology and biochemistry - Therapeutic alterations,
contractile state in heart failure
M POlHL-06308-18 Mechanisms and therapy of circulatory
disease
** POlHL-06308-18 0012 Mechanisms and therapy of
circulatory disease • Echocardiographic evaluation of
hemodynamics of arrhythmia (human)
** POlHL-06308-18 0042 Mechanisms and therapy of
circulatory disease - Echocardiographic assessment of
arrhythmias-Myocardial tissue type (human, dogs)
(contd)
HEA
POIHL 06308 18 0043 Mtchsnisms and Iheiapy ol
ciiculatoiy disaase Exercisa and achocardiotraphic
examminj techniques (human)
POIHI 06308 18 0044 Mechanisms and Iheiapy ol
ciiculatory disease tchocaidiography to deteimine sile ol
ectopic impulse toimalion (human, dogs)
POIHL 12?38 10 0094 Physiologic phaimacology and its
clinical applications Ventiiculai lunction and structure
(human, dogs)
P01HL1273810 0131
clinical applications
Physiologic pharmacology and its
Evaluation ol intracardiac shunts by
contrast echocardiography (dogs)
P50HL 1421407 0030 Newborn lung center lor hyaline
membrane disease EHects ot ductal patency Impedance
cardiography and echocardiography (human)
ROIHL 15016 07 New concepts in cardiac ultrasound
technology (human)
ROIHL 16487 05 Computer controlled two dimensional
echocardiography
R01HL16830-05 Noninvasive determination ol aortic
blood velocities (human)
P60HL 1726904 0027 National heart and blood vessel
research and demonstration center Non invasive
evaluation of cardiac tunction-ischemic heart disease
(human, dog)
P50HL1764804 0034 Study of ischemic hearl disease -
Data management-Hemodynamic data
P50HL-1766704 0030 Study of ischemic heart disease •
Computerized clinical data acquisition and processing
P50HL- 17669-04 0008 Ischemic heart disease center
(SCOR) • Segmental ventricular dysfunction during stress-
induced ischemia (dog, human)
P50HL17670-04 0014 Study of ischemic heart disease -
Real time ultrasound imaging in ischemic heart disease
(human, dog)
P50HL1768204 0014 Study of ischemic heart disease ■
Myocardial ischemia-instrumentation and technique (dogs,
baboons)
P50HL- 17682-04 0015 Study of ischemic heart disease
Acute myocardial ischemia and infarction and theii;
reversibility (dogs, baboons)
ROlHL-18144-03 Preprocessor system for cardiograms
(human)
P50HL-18323-D4 0012 SCOR hypertension center - Renin
as a risk factor (human)
POIHL- 18646-03 0008 Studies basic to heart
transplantation - Immunophysiology and early detection of
rejection (dogs)
ROlHL-18683-03 Left ventricle function in aortic
regurgitation (human)
ROlHL-19232-03 ECHO changes in wall motion with
myocardial ischemia
ROlHL-19246-03 Regression of cardiac hypertrophy-
Myocardial and renal (human)
ROlHL-19451-03 Functional characteristics of the left
heart
ROlHL-19451-03 0003 Functional characteristics ot the
left heart - Lett ventricular segmental contraction (human,
dogs)
The juvenile diabetic heart (human)
Multidimensional echo imaging of the
R01HL-20428-03
R01HL-20872-02
ischemic heart
R23HL-22787-01
Cardiac volume by biplane
echocardiography (human)
** ROlHL-22894-01 Two dimensional ultrasound and cardiac
surgery (human, dogs)
** NOlHR-62920-02 Noninvasive diagnosis of pulmonary
hypertension (dog, human)
HEART VISUALIZATION, EPICARDIAL MAPPING
ROlHL-21278-01 Abnormal cardiac wall motion viewed
ultrasonically (human, dogs, phantoms)
HEART VISUALIZATION, HEART SCANNING*
M POlHL-04664-18 Cardiovascular and lung dynamics
** POlHL-04664-18 0001 Cardiovascular and lung dynamics
- X-ray projection image videodensitometry (dogs)
POlHL-04664-18 0002 Cardiovascular and lung dynamics
- X-ray cross section imaging of organs (dogs)
** POlHL-04664-18 0003 Cardiovascular and lung dynamics
- X-ray projection image videometry (human, dogs)
** POlHL-04664-18 0004 Cardiovascular and lung dynamics
- X-ray cross section imaging of the circulation (dogs)
POlHL-04664-18 0006 Cardiovascular and lung dynamics
- Cross section imaging of organ functions using emitted
radiation (dogs)
POlHL-04664-18 0009 Cardiovascular and lung dynamics
- Biological signal and image processing techniques (dogs)
P01HL-06314-I7 0065 Immunologic mechanisms in
cardiovascular disease - Transplantation biology and
clinical transplantation
M POlHL-07293-17 Non-invasive cardiovascular
measurements
POlHL-07293-17 0041 Non-invasive cardiovascular
measurements Ventricular volumes and dimensions
(human)
** POlHL-07293-17 0042 Non-invasive cardiovascular
measurements - Ventricular imaging software (human)
** POlHL-07293-17 0043 Non-invasive cardiovascular
measurements - ECHO-Doppler instrumentation for cardiac
measurements (human)
** POlHL-07293-17 0044 Non-invasive cardiovascular
measurements - Cardiac duplex scanner
277
POIHI 0/293 1/ 0045 Non invjsivc cjrdiovditular
measurements Cardiac scanner transducer position
locating systems (human)
POIHL 07293 17 0046 Noninvasive cardiovascular
measurements Cardiac scanner signal processors
P01HL07293 17 004/ Non invasive cardiovascular
measurements Cardiac scanner system software
P01HL07293 17 0048 Non invasive cardiovascular
measurements Cardiac scanner recording and display
systems component
POIHL 0/293 17 0049 Non invasive cardiovascular
measurements Cardiac scanner engineering evaluation
and error analysis
P01HL07293 17 0050 Non invasive cardiovascular
measurements Cardiac dimensions measurements
engineering evaluation and error analysis
POlHL-07293 17 0051 Non invasive cardiovascular
measurements Physiologic evaluation of duplex scanner
(dogs)
POlHL-07293-17 0052 Non-invasive cardiovascular
measurements Clinical evaluation of the duplex scanner
(human)
' POlHL-07293 17 0053 Non invasive cardiovascular
measurements ■ Clinical evaluation of cardiac dimensions
using the duplex scanner (human)
ROlHL-09914-13 The myocardium in diabetes mellitus
(dogs, monkeys)
POlHL-10436-13 0002 A multidisciplinaiy study of
congenital heart disease Myocardial performance,
metabolism and ultrastructure (human, cats, rats)
POlHL-11310-12 0055 Mechanisms of cardiovascular
disease Ventricular pressure-volume after intracardiac
surgery (human)
POlHL-1 13 10-12 0081 Mechanisms of cardiovascular
disease Analysis of regional left ventricular function
(human)
* ROlHL-12322 10 Extrinsic factors influencing myocardial
performance (dogs, swine)
* ROIHL 13036-08 Coronary thrombosis-Effects on
myocardium and in vivo detection (dogs, monkeys)
* POlHL-13851-16 Cyclotron produced isotopes in biology
and medicine (human, animals)
POlHL-15194-07 0017 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation and
effects of arteriographic lesions on flow (human)
P60HL-17269-04 0026 National heart and blood vessel
research and demonstration center Dynamics of ischemic
heart disease (human, dog)
* P50HL- 17646-04 0009 Study of ischemic heart disease -
Regional metabolic derangements indicating ischemia
(rabbit, dog, human)
'* P50HL- 176 48-04 0004 Study of ischemic heart disease -
Radionuclide imaging studies (human, pig)
P50HL-17648-04 0006 Study of ischemic heart disease -
Ventricular performance and myocardial perfusion in
obstructive coronary disease
P50HL-17648-04 0034 Study of ischemic heart disease -
Data management-Hemodynamic data
'* P50HL-17651-04 0038 Ischemic heart disease specialized
center of research - Cardiothermography (human, dog)
P50HL-17655-04 0006 Study of ischemic heart disease ■
Evaluation of coronary artery bypass graft surgery (human)
** P50HL-17655-04 0011 Study of ischemic heart disease -
Core facility-Cardiovascular nuclear medicine (human, dog)
** P50HL-17665-04 0027 Study of ischemic heart disease ■
Positron imaging of regional myocardial perfusion (human,
dog)
P50HL-1 7667-04 0030 Study of ischemic heart disease -
Computerized clinical data acquisition and processing
** P50HL-17669-04 0009 Ischemic heart disease center
(SCOR) - Infarct volume-99Tc stannous pyrophosphate
myocardial scintigrams (dogs, human)
P50HL-17669-04 0022 Ischemic heart disease center
(SCOR) - Pathological studies of human and experimental
ischemic heart disease
** P50HL-17669-04 0023 Ischemic heart disease center
(SCOR) - Patients with acute myocardial infarction and
myocardial ischemia (human)
** P50HL- 176 70-04 0015 Study of ischemic heart disease -
Radionuclide studies of myocardial ischemia (human)
** P50HL-17670-04 0020 Study of ischemic heart disease -
Radionuclide evaluation of coronary artery disease (human,
dog)
P50HL-17682-04 0005 Study of ischemic heart disease -
Regional myocardial perfusion deficits and segmental
contraction disorders in man
P50HL-17682-04 0011 Study of ischemic heart disease -
Nuclear medicine core unit (human, dogs, rabbits, mice)
** ROlHL-18492-03 Measurement of regional coronary flow
reserve (human, dogs)
** P01HL-18646-03 0008 Studies basic to heart
transplantation - Immunophysiology and early detection of
rejection (dogs)
** P01HL-18708-03 0010 Oxygen, energy and contractility in
cardiac tissue - Tissue oxygen utilization (rats, dogs)
** ROlHL-18873-02 Early radiologic diagnosis ot cardiac
failure (monkey)
ROlHL-18968-03
tomography
ROlHL-19127-03
imaging (rats)
Computer technology for transaxial
Synthesis of molecules for myocardial
HiA
KOIHI 19115 04 Heterogeneity ol regional myociidlll
blood flow (dogs)
ROIHL 1923? 03 ECHO changes in wall motion with
myocardial ischemia
ROIHL 19289 03 Assessment ot infusion methods lor
myocardial mapping (dogs)
ROIHl 19451 03 0001 funclional characteristics ol the
left heart Ventricular performance using epicardial
radiopaque markers (human)
ROIHL 19451 03 0003 Functional characteristics of the
left heart Left ventricular segmental contraction (human,
dogs)
ROIHL 19451 03 0004 Functional characteristics of the
left heart Quantitative coronary arteriography (human)
ROIHL 19537 03 Detection of myocardial injury with
ultrasound (dogs)
ROIHL 20283 02 Maintenance of cellular integrity in
ischemic hearts (cats)
ROIHL 2089503 0001 Cineangiographic studies of
cardiovascular system Videodensitometry and valvular
regurgitation (human, dogs)
■ ROIHL 20895 03 0002 Cineangiographic studies of
cardiovascular system Coronary disease Regional
myocardial blood flow (human, dog)
ROIHL 20895-03 0005 Cineangiographic studies of
cardiovascular system Computerized axial tomography
Cardiac wall motion and infarction (dogs)
• P50HL-2 1006-02 0005 Specialized center of research in
arteriosclerosis Regional myocardial perfusion in patient
with coronary artery disease (also dogs)
R23HL 21253-01
image analysis
Anatomical models in computer-aided
Development of 99 mTc myocardial
ROlHL-21276-02
imaging agents
ROlHL-21278-01 Abnormal cardiac wall motion viewed
ultrasonically (human, dogs, phantoms)
ROIHL 21684-02 Radionuclide infarct sizing and therapy
evaluation
ROlHL-21684-02 0001 Radionuclide infarct sizing and
therapy evaluation ■ Evaluating preservation of ischemic
myocardium by radioisotope methods (dog)
ROlHL-21684-02 0002 Radionuclide infarct sizing and
therapy evaluation - Evaluating myocardial imaging agents
in global and regional ischemia (rabbits)
ROlHL-2 1684-02 0004 Radionuclide infarct sizing and
therapy evaluation - Image analysis -Kinetics of infarction,
ventricular function (human, animal)
ROlHL-21684-02 0005 Radionuclide infarct sizing and
therapy evaluation - Clinical evaluation of radioisotope
imaging methods for quantifying infarct size
' ROlHL-21690-02 Sequential multinuclide study of acute
infarction (human, dogs)
' ROlHL-21697-01 Myocardium infarct sizing by 82Rb
emission tomography (dogs, human)
' ROlHL-21707-01 Quantification of infarct size by emission
tomography (human, dogs)
■ ROlHL-21719-01 Computed cardiac tomography in infarct
sizing (dogs, human)
ROlHL-21751-02 Thallium and antimyosin in ischemia and
infarction
Thallium and antimyosin in
- In vitro models of ischemia and
ROlHL-21751-02 0001
ischemia and infarction
infarction (rats, mice)
ROlHL-21751-02 0002
ischemia and infarction
infarction
ROlHL-21751-02 0003
ischemia and infarction
infarction
ROlHL-21793-02 Functional infarct size by gated
radioangiography (human, dogs)
R23HL-22004-01 Imaging and ECG studies in acute and
chronic IHD (human)
ROlHL-22750-01
rhythm (human)
Thallium and antimyosin in
- Canine models of ischemia and
Thallium and antimyosin in
- Human studies-Ischemia and
ROlHL-23653-01
(dogs)
NOlHV-62960-00
Digoxin in heart failure with sinus
Protection of the ischemic myocardium
Techniques to protect ischemic
myocardium and minimize infant size (human)
HEART VISUALIZATION, RADIOCARDIOGRAPHY*
ROlHL-15016-07 New concepts in cardiac ultrasound
technology (human)
ROlHL-15781-06 Guided vascular obliteration of CNS
vascular lesions (human)
P50HL-17682-04 0011 Study of ischemic heart disease -
Nuclear medicine core unit (human, dogs, rabbits, mice)
ROlHL-18968-03 Computer technology for transaxial
tomography
** ROlHL-19127-03 Synthesis of molecules for myocardial
imaging (rats)
ROlHL-19451-03 0001 Functional characteristics of the
left heart - Ventricular performance using epicardial
radiopaque markers (human)
ROlHL-20674-02 Evaluation of cardiac function with
radioactive tracers
ROlHL-23201-01 Mechanisms of hypertension (human.
rats)
** ROlHL-23983-01 Quantitative radiocardiography (human,
dogs)
NOlHV-7293002 Atherosclerosis assessment-Angiography
and ultrasound (dogs, human)
(contd)
•Excludes routine methodotogy OR covers only general projects which preclude indexing at the specific level.
••Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number
HEA
HEAT
SEE TEMPERATURE. HEAT
HEAT EXHAUSTION
SEE INJURIES. TEMPERATURE DEPENDENT, HEAT INDUCED
HEAT INJURY
SEE INJURIES, TEMPERATURE DEPENDENT, HEAT INDUCED
HEAT STABILITY-LABILITY
SEE TEMPERATURE. HEAT STABILITY-LABILITY
HEAT STIMULUS
SEE TEMPERATURE, HEAT, CALORIC STIMUUTION
HEAT STRESS
SEE ENVIRONMENT, STRESS, HEAT INDUCED
HEATING, AIR CONDITIONING, VENTILATION
SEE ENVIRONMENT CONTROLLED
HEAVY METALS
SEE METALS, HEAVY METALS
HELA CELLS
SEE NEOPUSTIC CEUS, HELA CELLS
HEUUM
SEE GAS ELEMENTS, HELIUM
HELMINTH ANTIGENS
SEE IMMUNOLOGY, ANTIGENS HELMINTHIC
HELMINTH INFECTIONS
SEE PARASITIC DISEASES, HELMINTH INFECTIONS (GENERAL)
HELMINTHS, ANNELIDS, LEECHES
SEE ALSO BLOOD COAGULATION, HIRUOEN
** ROlHL-22227-01 A new source of hyaluronldase and
anticoagulants (leeches)
HELMINTHS, NEMATODES, ASCARIS
" POIHL- 10342- 13 0028 The integrated function of
respiration and circulation - Mediator release,
hemodynamics and respiratory function in anaphylaxis
(dogs)
HELPER T LYMPHOCYTES
SEE BLOOD CELLS, T LYMPHOCYTES. HELPER
HEMAGGLUTINATION
SEE IMMUNOLOGICAL TESTS AND IMMUNOASSAY.
HEMAGGLUTINATION*
HEMAGGLUTINATION INHIBITION
SEE IMMUNOLOGICAL TESTS AND IMMUNOASSAY.
HEMAGGLUTINATION INHIBITION*
HEAAAGGLUTININS (ANTIBODY)
SEE IMMUNOLOGY, ANTIBODIES, HEMAGGLUTININS
HEAAAGGLUTININS (PLANT)
SEE PLANTS PROTEINS. LECTINS
HEAAANGIOENDOTHELIOMA
SEE NEOPUSMS OF CARDIOVASCULAR SYSTEM.
HEMANGIOENDOTHELIOMA
HEAAANGIOMA
SEE NEOPUSMS OF CARDIOVASCULAR SYSTEM.
HEMANGIOMA
HEAAATOCRIT
SEE BLOOD (HEMATOLOGIC) TESTS, BLOOD CELL COUNT*
HEMATOLOGIC AGENTS
SEE BLOOD AND RE DRUGS (GENERAL)
HEAAATOLOGIC TESTS
SEE BLOOD (HEMATOLOGIC) TESTS*
HEAAATOLOGY
SEE BLOOD AND RE SYSTEM. HEMATOLOGY
HEAAATOLOGY STUDY SECTION
" R01HLOI601-30 Blood coagulation and hemorrhagic
disease (horseshoe crabs)
** R01HL'Oie48-31 Blood coagulation and hemophilia (dogs.
swine)
** ROlHL-01661-27 Hemostatic mechanisms (human)
** ROlHL-02254-23 Blood coagulation and hemorrhagic
disease (human, animals)
** ROlHL-02262 23 Mechanisms regulating plasma proteins
and solutes (human, dogs)
** R01HL02799-22 Abnormal hemoglobins (human)
** R01HL03357-21 Humoral control of blood cell formation
and release (rats, mice)
** ROlHL-03424-21 Formation and properties of prothrombin
derivatives (human, animals)
** R01HL'04ei2'20 Feedback between red cell production
and oxygen transport (rabbits, rats)
** ROlHL-0516819 Inhomogencity of hemoglobin types
(human)
** ROlHL-05351-18 Blood group antigens and antibodies
(human, rabbits, sheep)
** R01HL05791-18 Structure and function in hemoglobins
(human)
** R01HL06242 18 Kinetic studies of blood (human)
278
ROlHL-0695017 Red cell metabolism (human,
vertebrates)
ROlHL-07379-13 Structure and function of fibrinogen
(human)
R01HL-07652-14 Destruction of red blood cells in
hemolytic anemias (human, guinea pigs)
R01HL-09902-13 Comparative study of coagulation and
vascular disease (animals)
R01HL'10036'13 Biology of red cell antigen-antibody
reaction (human)
R01HL-10567-12 Erythropoietin-Immunoassay and
characterization (dogs)
R01HL-10880-13
research use
R01HL-1I154 12
(human)
ROlHL-1 11 72-12 Physiology and biochemistry of
fibrinolytic enzymes (human, animals)
ROlHL-1 1686-09 Dynamics of thrombus formation and
dissolution (human, chickens)
ROlHL-11775-11 Platelet mechanisms in disease (human,
primates)
ROlHL-1 1880-10 Physiology and pathology of blood
platelets (human, dogs)
ROIHL- 128 20-09 In vitro regulation of prothrombin
activation
ROlHL-12944-09 Enzymatic and biochemical studies on
blood cells (human)
Purification of human erythropoietin for
Blood group antigens and antibodies
ROlHL-12972-09
(sheep, dogs)
ROlHL-12994-09
ROlHL-131 60-08
ROlHL-13198-21
Glutathione deficiency In red cells
The Rh complex of red cells (human)
Human thrombin (also cattle)
Blood coagulation-Physico-chemical
properties (human, cattle)
ROlHL-13336-09 Biochemistry and physiology of human
platelets
R01HL13423-08 Structure-function studies of plasminogen
and plasmin (human)
ROlHL-13585-05 Heterogeneity of NADH methemoglobin
reductase (human)
ROlHL-13629-08 Hemorrhagic diseases (human)
ROlHL-1388108 The American Red Cross National
Fractionation Center
ROlHL-14131-18 Abnormal hemoglobin syndromes
(human)
R01HL-14344-07 Platelet function and adenine nucleotide
metabolism (human)
R01HL-14595-07 Primary disorders of platelet function
(human, rats)
R01HL-14637-0S Thrombopoietin-lmmunoassay and
characterization (mice)
R01HL-14697-07 Role of platelet membranes in
hemostasis (human)
ROlHL-14739-06 The role of leukocytes in thrombotic
disease (human, dogs)
R01HL14847-07 Mechanism of action of vitamin K and
anticoagulants (rats)
ROlHL-14890-07 Platelet prostaglandins (human, rabbits)
ROlHL-14992-07 Mechanism of thrombin action (human)
ROlHL-152 15-06 Role of complement in intravascular
coagulation (rabbits, mice)
ROlHL-15226-06 Interaction of blood cells with fibrinogen
and fibrin (human, animals)
R01HL-15230-05 Molecular basis of V Willebrand's disease
and hemophilia (human, cattle)
ROlHL-15335-06 The nature of the collagen-platelet
interaction (animals)
ROIHL- 154 74-06 Structure and function of the
antihemophilic factor (human, cattle)
ROlHL-15491-06 Blood coagulation-Platelet-plasma
protein interaction (human)
ROlHL-156 15-06 Structure-function studies of human
factor VIII/vWF
ROlHL-15616-04 Platelet membrane proteins in
aggregation (human)
R01HL-15619-05 Regulation of prothrombin synthesis in
cultured cells (rats)
R01HL-15647-06 Hematopoietic studies of cyclic
hematopoiesis (dogs)
R01HL-15685-05 Hemopoietic regulators produced in cell
culture (human, animals)
R01HL-15690-07 Hydrolytic enzymes of blood in health
and disease (human, animals)
ROlHL-15728-06 The carbohydrate of the blood-clotting
glycoproteins (mammals)
ROlHL-15793-06 Molecular aspects of erythrocyte
membrane resealing (human)
ROlHL-15817-06 Plasminogen activators from tissues
(human, pig, cattle)
ROlHL-15887-05 Enzymes of blood coagulation and
fibrinolysis (human)
ROlHL-161 50-05 Primary structure of prothrombin (cattle.
human)
ROlHL'16238-05 Protein structure in coagulation and
fibrinolysis (human)
ROlHL-16346-09 Enzyme assay for blood clotting (human)
ROlHL-16355-05 Reactions of thrombin and collagen with
platelets (human)
ROlHL-16361-03 Fibrin complexes in intermediary
coagulation (human, rabbits)
ROlHL-16375-04 Investigation of hemoglobin S properties
(human)
Pathobiology of thromboembolic disorders
Regulation in developing erythroid cells
Human urinary erythropoietin collection
Platelet aggregation (human)
'Autoimmune' thrombocytopenia (monkey)
Antihemophilic factor (human)
Proteins of blood coagulation (human.
Red cell storage and transfusion
HEM
ROlHL-16421-08 Determinants of RBC deformability and
capillary flow (human, mice)
R01HL-ie633-04 Chemistry and biology of factor IX
activator (human, mice, rats)
ROlHL-16642-05 Biochemistry and pathophysiology of
plasma kallikrein (human, animals)
ROIHL- 16646-05
(human)
R01HL16654-06
(human)
ROlHL-16675-05
ROlHL-16720-02
R01HL-16757-04
ROlHL-16872-04
ROlHL-16919-05
bovine)
ROlHL-16931-04
(human, animals)
R01HL-169S5-05 Heparin, blood coagulation and lipid
metabolism (human)
ROlHL-17513-04 Role of PF-4 In detecting and promoting
thrombosis (human, primates)
ROlHL-17726-03 Bacterial heparlnase in diagnostic
coagulation studies
ROlHL-17729-04 Stimulus-response coupling in platelets
(human)
ROlHL-17752-03 Purified human clotting factor IX-
Immunologic studies (human)
ROlHL-17881-15 Biosynthesis and degradation of blood
group substances (human, animals)
R01HL-17930-03 Platelet membrane function-Assessment
and application (animals)
ROIHL- 17964-04 The alternate pathway for fibrinolysis
(human)
ROlHL-18012-04 Cellular defects in nocturnal
hemoglobinuria (human)
ROlHL-18030-04 The role of contractile proteins in
platelets (human, rabbits)
ROlHL-18068-02 Chemistry and activrty of homologous
heparin fractions (rodents)
R01HL18082-03 Erythrocyte phosphates and vertebrate
gas transport (amphibians, reptiles)
ROlHL-18249-04 Isolation and identification of platelet
membrane (human)
ROlHL-18284-04 Aging erythrocytes-Bio-recognition and
elimination (monkeys)
ROlHL-18333-05 Thrombogenesis and hemostatic balance
(rabbits, human)
ROlHL-18435-03 Properties of thrombin and Ac-globulin
(human, animals)
Enzymatic regulation of platelet function
Clinical studies of Fletcher factor
ROlHL-18502-03
(human)
ROlHL-18507-03
(human)
ROlHL-1855103 Spectrin, actin. lipid and red cell
membrane structure
ROlHL-18584-03 Effects of physical forces on platelets
(human)
R01HL-18S8e-03 Role of platelet lipids in hemostasis and
thrombosis (human)
ROlHL-18618-04 Purification and function of human HMW
kininogen
ROlHL-18650-03 Platelet collagen interaction (human)
ROlHL-18672-03 Dynamic studies of clot structure
formation (human)
ROlHL-18834-04 Metal-dependent complex formation in
blood coagulation (human, cattle)
R01HL-188S2-03 Biochemical studies on the blood
coagulation process (human, cattle)
ROlHL-18859-03 Biochemistry of human factor XI (human)
ROlHL-18935-03 Platelets, fibrinogen, soluble fibrin
interaction (human)
ROlHL-18937-03 Cyclic nucleotides and calcium in
platelets (human)
ROlHL-19105-02 Detection and adherence of fibrin
monomer complexes (human)
ROlHL-19131-04 Hypercoagulability and assays for its
protection (human)
R01HL-19267-02 Serial comparative study of Von
Willebrand's disease (human)
ROlHL-19270-03 Effects of erythropoiesis on platelets and
hemostasis (rats)
ROlHL-19272-03
ROlHL-19278-03
(human)
ROlHL-19282-03
factor X
ROlHL-19322-03
Studies on the Passovoy factor (human)
Ristocetin induced platelet aggregation
Regulation of the activation of human
of vitamin K (rats)
Role of pituitary hormones in the action
ROlHL-19323-03
ROIHL- 19324-02
by DBA (human)
R01HL-19331-03
R01HL-19333-03
ROlHL-1964603
variation in man
ROlHL-19767-01
ROlHL-19933-02
Studies of platelet microtubule protein
Mechanisms of the inhibition of sickling
Hirudin Isolation and utilization (leeches)
Hematopoietic chimerism (mice, monkey)
An immunologic study of hemoglobin
'Excludes routine methodotogy OR cavers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
Pathochemistry of fibrinogen (humans)
Membrane and red cell dysfunction in
hemolytic anemia (human)
ROlHL-19996-02 Role of membrane proteins in platelet
function (human, rabbits)
(contd)
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
HfM
279
HIM
" ROIHL 2001402 Radlolmmunotssay ol hyper and
hypocoagulabl* statas (rabbits)
** R01H12OOMO2 Structurt and (unction ol amidinatad
human hemoglobin
** ROIHl'20092 02 Structural and biological properties ol
llbiinogan (human, rabbits)
** R01Hl'201M'02 Collagen platelet interaction and human
aorta collagen (human)
** ROIHI 2014002 Glycoproteins ot platelet membrane and
platelet function (human)
** ROIHI 20141 02 Biochemical approaches to management
of iron overload (human, sheep, dogs)
** ROIHL 2014202 Functional studies ol abnormal human
hemoglobins
** R01HL2021802 Fibrinogen catabolism and intravascular
coagulation (human)
** ROIHL 20303-03 Cholesterol distribution in erythrocyte
membrane (human, animals)
** ROIHL'20317 02 Procoagulant lipoproteins-Blochemistry
and bioactivity (goats, rabbits)
** ROIHL 2057703 The mechanism ol action ol vitamin K
** ROIHL'20750'01 Studies in sickle cell disease (human)
*• ROIHL 2082602 Megakaryocyte proliteration and its
control (mice)
** R01HL-2084e-02 Purilication of bovine plasminogen
proactivator
** ROlHL-2092001 Control ol hemoglobin synthesis (baboon)
** ROIHL 20925 01 The acetylation of letal hemoglobin
(human)
" R01HL'2097MO Membrane glycoproteins of platelets and
leukocytes (human)
** ROIHL'21113-Ol Control mechanisms in coagulation
(cattle)
** R23HL-21128-02 ATP utilization in platelet contractile
mechanisms (human, rabbits)
** R23HL-2 11 29-02 The antisickling etiects of imidoesters
** ROlHL-2113902 Molecular biology of factor XIII (human)
** R23HL-2 1208-02 Structure-function relationships ol human
lactor VIII
*• ROlHL-21379-01 Structure of lactor Vlll-Von Willebrand
protein (human)
** R23HL-2 1428-02 Expression ol human globin In
thalassemia (human)
** ROlHL-21431-02 Factor II antigen and coagulant activity
(human, animals)
•• ROlHL-21469-01 Active transport and effect of CAOO in
sickle cell (human)
** ROlHL-21487-01 Molecular characterization of
Glanzmann's thrombasthenia (human)
** R23HL-2 1490-02 Studies of enzymes in human platelet
membranes
** ROlHL-21543-02 Structure-function relation of blood
clotting proteins (rabbits)
** ROlHL-21544-02 Proteins of coagulation and Hageman
factor pathways (human, goats)
** R23HL-21730-01 vWagll-A new vWD deficient antigen
(human)
** R01HL-2197S-01 Studies on normal and abnormal factor
IX (human, dogs, cows)
** ROlHL-2 1988-01 Biochemistry of human platelet
chemotaxis
** R01HL-2203S-01 Molecular modification of heparin by
chemical means (sheep)
** ROlHL-221 19-01 Biochemistry of platelet function in
thrombosis and cell growth (rabbits)
** ROlHL-22227-01 A new source of hyaluronidase and
anticoagulants (leeches)
** ROlHL-22289-01 Endothelial cell mediated fibrinolysis
(rabbits)
** ROlHL-22355-01 Purification, structure and function of
factor VIII (human)
** ROlHL-22471-01 Biochemistry of prothrombin quick
(human)
" ROlHL-22502-01 Role of phosphoinositides in human
platelet secretion
** ROlHL-22505-01 Molecular pathology of fibrinogen and
factor XIII (human, animals)
** R23HI-22621-01 Blood cell-mediated pulmonary (human)
** ROlHL-22650-01 Regulatory mechanisms of erythropoietin
production (human, rats, mice)
** ROlHL-22780-01 Factors modifying the reaction properties
of HgS (human)
** R23HL-22799-01 Interaction of the complement and
coagulation systems (monkeys)
** ROlHL-22951-01 Studies on the affect of vitamin E on
platelets (human, rats)
** ROlHL-22955-01 inetics of prothrombin activation
** ROlHL-22980-01 Kinetic and mechanistic studies of blood
coagulation (human, cattle)
** ROlHL-23108-01 Membrane biochemistry of RH antigens
(human)
** ROlHL-23200-01 Isolation of CA binding proteins from
erythrocytes (human)
** ROlHL-23736-04 Sickle cell anemia and hemoglobin
synthesis (monkeys)
*• R01HL-24O21-O2 Erythocyte membrane sulfhydrls and Rh
activity (human)
HEMATOPOIESIS
SEE BLOOD AND RE SYSTEM, HEMATOPOIESIS
HEMATOPOIETIC FACTORS
SEE BLCOD AND RE SYSTEM, HEMATOPOIETIC FACTORS
HEMATOPOIETIC STEM CELLS
Sff BIOOD CflLS. HrMAIOPOIftIC STEM CELLS (GENERAL)
HEMATOPOIETIC TISSUE
SEE BLOOD AND RE SYSTEM. HEMATOPOIETIC TISSUE
HEME
SEE ALSO HEMOPROTEINS
ROIHL I4S08 10 Structure and function of respiratory
hemoproteins
** ROIHL 1779403 Chelating agents as blood substitutes
POIHL 1870803 0003 Oxygen, energy and contractility in
cardiac tissue Structural functional studies on cytochrome
c oxidase
POIHL 18708-03 0010 Oxygen, energy and contractility in
cardiac tissue - Tissue oxygen utilization (rats, dogs)
ROlHL-21159-02 Pathophysiological effects of hypoxia
(rats)
" R01HL21461-01 Heme group protein interactions in
hemoproteins
** ROIHL 22252-01 Synthesis of labeled hemes for protein
NMR studies
HEME, FERRIHEME
ROlHL-13652 08 Metal sites In metalloproteins
(mushroom)
PeOHL-16005-OS 0013 Comprehensive sickle cell center -
Study of regulation of erythropoiesis in vitro (human, rat,
hamster, rabbit)
R01HL-ie931-04 Red cell storage and transfusion
(human, animals)
HEMERYTHRIN
SEE METALLOPROTEINS, HEMERYTHRIN
HEMOCHROMATOSIS
SEE METABOLIC DISORDERS INBORN. HEMOCHROMATOSIS
HEMOCHROMATOSIS, SECONDARY
SEE IRON DISORDERS AND IMBALANCES, HEMOSIDEROSIS
HEMOCHROMES, FERRIHEMOCHROMES
P60HL-15157-07 0012 Comprehensive center for sickle
cell disease - Sickling and intracellular pH (human)
HEMOCYANIN
SEE METALLOPROTEINS, HEMOCYANIN
HEMOCYTES
SEE BLOOD CELLS
HEMODIALYSIS
SEE BLOOD TREATMENT. HEMODIALYSIS
HEMODYNAMICS
SEE CARDIOVASCULAR FUNCTION. BLOOD CIRCUUTION
DYNAMICS (GENERAL)
HEMOERYTHRIN
SEE METALLOPROTEINS, HEMERYTHRIN
HEMOGLOBIN
SEE HEMOPROTEINS, HEMOGLOBIN
HEMOGLOBIN A2
SEE HEMOPROTEINS. HEMOGLOBIN A2
HEMOGLOBIN-BINDING ALPHA2-GLOBULIN
(SERUM)
SEE HEMOPROTEINS. HAPTOGLOBINS
HEMOGLOBIN C
SEE HEMOPROTEINS. HEMOGLOBIN C
HEMOGLOBIN D
SEE HEMOPROTEINS, HEMOGLOBIN D
HEMOGLOBIN F
SEE HEMOPROTEINS, HEMOGLOBIN F
HEMOGLOBIN H
SEE HEMOPROTEINS, HEMOGLOBIN H
HEMOGLOBIN S
SEE HEMOPROTEINS, HEMOGLOBIN S
HEMOGLOBINOPATHIES
SEE HEMOPROTEINS, HEMOGLOBINOPATHIES
HEMOLYSINS
SEE BLOOD TOXICOLOGY, HEMOLYSINS
HEMOLYSIS
SEE BLOOD CELLS, ERYTHROCYTES, HEMOLYSIS
HEMOLYTIC ANEMIA
SEE BLOOD AND RE DISORDERS, ANEMIA HEMOLYTIC
HEMOLYTIC ANEMIA CONGENITAL (FAMILIAL)
SEE BLOOD AND RE DISORDERS, ANEMIA HEMOLYTIC
CONGENITAL (GENERAL)
HEMOPHILIA
SEE BLOOD COAGUUTION DISORDERS, HEMOPHILIA
HEMOPHILIA B
SEE BLOOD COAGULATION DISORDERS, CHRISTMAS DISEASE
HEMOPHILIA C
SI I BLOOD COAGULATION DISORDERS, FACTOR XI
DfflCIFNCY
HEMOPROTEINS
SEE ALSO PEROXIDASES
** ROIHL 1252609 Raman spectra of heme proteins and
related molecules
** ROIHL 13531 06 Coboglobins Cobalt subsliluled myo and
hemoglobins
" ROIHL 13581 II Reactions of oxygen with heme proteins
** ROIHL 13651 07 X ray pholoelectron spectroscopy of heme
compounds
** ROIHL 1398905 Role of water in respiratiory protein
structure
POIHL 14388 07 0175 Regulation ol the circulation in
pathological states Functional studies ol selected proteins
Irom cardiac muscle
** ROIHL 14508-10 Structure and lunction ol respiratory
hemoproteins
" ROIHL 15980-06 Reactions ol hemoproteins and oxygen
(cattle)
** ROIHL 16087-05 Structural and dynamic study of model
heme complexes (yeast)
" ROlHL-16860-05 Mossbauer studies of respiratory
hemoproteins
ROIHL- 17826-04 Oxygen delivery to tissue (rat. dog)
** ROlHL-21461-01 Heme group protein interactions in
hemoproteins
ROIHL 22252-01 Synthesis of labeled hemes for protein
NMR studies
HEMOPROTEINS, CYTOCHROME
** POIHL 07896-15 0019 Environmental biomedical research
program Hyperoxic myopia (human)
P01HL-0789e-15 0032 Environmental biomedical research
program Fluorometry study of brain exposed to hyperbaric
oxygen (dogs, cats)
" POlHL-07896-15 0051 Environmental biomedical research
program - Relationships of retinal circulation to disease
(rabbits)
ROlHL-14508-10 Structure and function of respiratory
hemoproteins
R01HL-1S655-05 Blood flow and gas exchange in placenta
and lungs (sheep) rabbits)
ROlHL-18304-03 FT-infrared spectroscopy of heart muscle
energetics (cattle)
POlHL-18708-03 0007 Oxygen, energy and contractility in
cardiac tissue - Surfaces, energy requirements, and
contractile proteins of cardiac cell in vitro
ROlHL-19392-03 Spectroscopic studies of respiratory
metalloproteins
ROlHL-19481-03 High-field NMR studies of respiratory
proteins (human, horse, fish, microbes)
ROlHL-22252-01 Synthesis of labeled hemes for protein
NMR studies
POlHL-22619-01 0010 Cellular mechanisms of heart
failure - Mitochondria in heart and smooth muscle (rabbits,
rats, dogs)
HEMOPROTEINS, CYTOCHROME A
ROlHL-16686-04 Properties of cytochrome oxidase (cattle,
bacteria)
ROlHL-17559-03 Structural elucidation of heart
cytochromeC oxidase
HEMOPROTEINS, CYTOCHROME B
ROlHL-13585-05 Heterogeneity of NADH methemoglobin
reductase (human)
ROlHL-13619-09 Microsomal electron transport in liver
and heart (human, mammals)
P50HL 14217-08 0057 Specialized center of research in
thrombosis - Pharmacology-Platelet biochemistry (human,
animal)
ROlHL-14483-08 Energy conservation in heart
mitochondria (cattle, E coll, human)
HEV^PROTEINS, CYTOCHROME C
P01HL12157-11 0051 Functions and mechanisms of cell
membrane ion transport - Electron transport in the red cell
membrane (human, guinea pigs)
ROlHL-13651-07 X-ray photoelectron spectroscopy of heme
compounds
ROlHL-13652-08 Metal sites in metalloproteins
(mushroom)
ROlHL-14483-08 Energy conservation in heart
mitochondria (cattle, E coli. human)
ROlHL-15104-07 A mechanism lor oxidative
phosphorylation
** ROlHL-16686-04 Properties of cytochrome oxidase (cattle,
bacteria)
ROlHL-17559-03 Structural elucidation ol heart
cytochrome-C oxidase
R23HL-19605-01 Lipid requirement of the lung mono-
oxygenase system (rabbits)
POlHL-20592-02 0010 Cell biology of cardiac and
skeletal muscle - Mitochondrial genesis during myocardial
cell hypertrophy and hyperplasia (rats)
ROlHL-22050-01 Organization of succinic oxidase in heart
HEMOPROTEINS, CYTOCHROME P450
ROlHL-06975-18 Pathogenesis and prevention of
hypertension (rats)
'Eidudn routine melhodokigy OR cavers only general pmjects which pmlude Indexing it the specific level.
"Oriented siinWcintly to above lubject-
M Grant has subprolects describing si
See Appendix for Investigator's name
pecific research aspects,
and grant number.
(cofltd)
HEM
** P01HL08899-14 0062 Tolerance to respiratory gases in
healtti and disease - Influence of oxygen at high pressure
upon oxidation (rats)
POlHL-10342-13 0014 The integrated function of
respiration and circulation - Oxygen and carbon monxide
transfer (human, dogs, sheep)
** P01HL1034213 0024 The integrated function of
respiration and circulation - Cytochrome P450 and
physiological response to hypoxia (rats)
ROlHL-12526-09 Raman spectra of heme proteins and
related molecules
R01HL13399-16 Heme protein structure and function
(human, horse, plants, bacteria)
R01HL13531-06 Coboglobins-Cobalt substituted myo- and
hemoglobins
R01HL13619-09 Microsomal electron transport in liver
and heart (human, mammals)
ROlHL'13652-08 Metal sites in metalloproteins
(mushroom)
POIHL 1438807 0175 Regulation of the circulation In
pathological states - Functional studies of selected proteins
from cardiac muscle
ROlHL-1501307 Lung oxidative metabolism and energy
production (rodents, rabbit
ROlHL-15980-06 Reactions of hemeproteins and oxygen
(cattle)
R23HL-19605-01 Lipid requirement of the lung mono-
oxygenase system (rabbits)
ROlHL-19772-02 Role of warfarin metabolism In
antlvitamin K activity (rats)
ROlHL-20176-02 Biochemistry and genetics of salt
hypertension (rats)
HEMOPROTEINS, HAPTOGLOBINS
** ROlHL-16445-05 Regulation of plasma protein
biosynthesis (rats, rabbits)
ROlHL-16601-05 Structure and function of blood proteins
(human, cattle)
PClHL-21016-02 0014 Sickle cell anemia and other
hemoglobinopathies - Human hemoglobin mutants with
abnormal oxygen binding
HEMOPROTEINS, HEMOGLOBIN
SEE ALSO BILE PIGMENTS
SEE ALSO HEMOPROTEINS, HEMOGLOBINOPATHIES
SEE ALSO HEMOPROTEINS, MYOGLOBIN
NOlHB-22919-08 Hemoglobin carbamylation in the
treatment of sickle cell anemia (human, dogs)
ROlHL-02558-22 Structure-function relationships in the
heme proteins (human, cattle)
ROlHL-02799-22 Abnormal hemoglobins (human)
ROlHL-03290-22 Controls of cardiac and vascular smooth
muscles (cats, rats, dogs)
** ROlHL-05168-19 Inhomogenclty of hemoglobin types
(human) i
** ROlHL-05556-19 Protelns,^lipoprotelns-Structure and
reactivity (chicken, human, diving mammals)
** ROlHL-05791-18 Structure and function In hemoglobins
(human)
POlHL-06314-17 0050 Immunologic mechanisms In
cardiovascular disease - Physiologic changes in
lymphocytes (human, mice)
** ROlHL-07451-16 Hemoglobin S gelation and hemoglobin
allostery (human)
** ROlHL-07652-14 Destruction of red blood cells In
hemolytic anemias (human, guinea pigs)
POlHL-08805-15 0025 Regulation of ventilation and
pulmonary circulation - Pulmonary edema (rabbits)
POlHL-08899-14 0010 Tolerance to respiratory gases in
health and disease - High oxygen pressure In septic shock
(human)
** ROlHL-09906-13 0019 Membrane transport processes In
red blood cells - Hemoglobin change and membrane
potentials in red blood cells at varying volumes
** ROlHL-10383-12 Physical-chemical studies of hemoglobins
and erythrocyte (human)
ROlHL-12174-11 Ventllation/perfusion distribution in the
lung (human, mammals)
ROlHL-12256-15 Polymerization of sickle-cell hemoglobin
(human)
** R01HL-12524-10 Reaction of hemoglobin with llgands and
antibodies (human, carp)
ROlHL-12526-09 Raman spectra of heme proteins and
related molecules
*• ROlHL-13157-09 Molecular oxygen carriers-Synthesis,
structure, bonding
** ROlHL-13164-07 Interaction of the alpha and beta chains
of human hemoglobin
ROlHL-1339916 Heme protein structure and function
(human, horse, plants, bacteria)
ROlHL-13531-06 Cobogloblns -Cobalt substituted myo- and
hemoglobins
ROlHL-13581-11 Reactions of oxygen with heme proteins
ROlHL-14127-16 Methemoglobinemia and antihypertensive
drugs (cats, mice, rats)
P50HL-14236-05 0006 Prevention of premature
arteriosclerosis - Carbohydrate metabolism and
hypertriglyceridemia (human)
POlHL-14414-07 0014 Environmental Influences on
cardiorespiratory and cellular functions Temperature and
acid-base status In tissues, cells, and subcellular system
ROIHL-14508-10 Structure and function of respiratory
hemoprotelns
280
ROlHL-14680-07 Specific enrichment of myoglobins for
carbon 13 NMR (catacea)
ROlHL-15026-12 Quantitative genetic control of protein
synthesis (human, primates, mammals)
P60HL-1 5 158-07 0008 Comprehensive sickle cell center -
Core laboratory of the center
P60HL-15158-07 0014 Comprehensive sickle cell center -
Mechanism of sickling in human and deer hemoglobins
P60HL-15158-07 0016 Comprehensive sickle cell center -
Biochemical studies In sickle cell anemia (human)
P60HL-151 58-07 0020 Comprehensive sickle cell center
Immunochemical investigation of hemoglobin variants
(human)
P60HL-15170-05 0017 Support for center for sickle cell
anemia - Control of hemoglobulin synthesis (human)
POlHL-15194-07 0006 Pathophysiology of
cardiopulmonary dysfunction - Kinetics of gas exchange -
Velocity of Bohr effect In erythrocytes (human)
POlHL-15194-07 0009 Pathophysiology of
cardiopulmonary dysfunction - Kinetics of gas exchange -
Diffusion and erythrocytes reaction rates (human, dogs)
ROlHL-15284-06 Hemoglobin and myoglobin kinetic
studies (human, animals)
ROlHL-15460-06 Molecular adaptation-Hemoglobin
systems of fish (marine)
ROlHL-15627-06 X-ray and chemical studies of
metalloporphyrlns
ROlHL-15980-06 Reactions of hemeproteins and oxygen
(cattle)
' P60HL- 15999-05 0019 Miami comprehensive sickle cell
center - Fetal-adult hemoglobin switch (mouse, monkey)
' ROlHL-16093-05
erythrocytes
ROlHL-16375-04
(human)
R01HL-16490-04
(rats, rabbits)
ROlHL-16601-05
(human, cattle)
POlHL-16833-04
hemoglobinopathies
' POlHL-16833-04 0011 Hemoglobin and red cell system In
hemoglobinopathies - Relationship between hemoglobin and
RBC membrane In sickling cells (human, rats)
' POlHL-16833-04 0015 Hemoglobin and red cell system In
hemoglobinopathies - Stereochemistry of hemoglobins from
magnetic circular dichroism (human)
POlHL-16833-04 0016 Hemoglobin and red cell system in
hemoglobinopathies - Calcium-lndlced membrane damage
in Hb SS disease (human, animals)
ROlHL-16860-05 Mossbauer studies of respiratory
hemoprotelns
* ROlHL-16891-05 The folding of hemoglobin
* ROlHL-16927-05 Structure and function of normal and
abnormal hemoglobin (human)
* ROlHL-17494-07 Mechanism of liqand binding to
hemoglobin (human)
* ROlHL-177 10-04 Selective replication of hemoglobin genes
(mice, ducks, human)
ROlHL-17844-04 Artificial blood substitutes-02-blnding
iron chelates (human, mammals)
ROlHL-17967-04 Limiting factors in oxygen uptake in the
lung
ROlHL-18163-04 Red cell membrane effects due to
oxidizing agents
POlHL-18208-04 0006 Center for the study of blood cell
rheology - Analysis of flow In arterioles and capillaries
(human)
* R01HL18226-04 Mechanism of oxygen supply to tissue
(human, animals)
* ROlHL-18309-04 Oxygen transport-Hemoglobins with
modified hemes (horse)
* ROlHL-18328-03 Hemoglobin function and tissue
oxygenation (human, dogs)
POIHL- 186 46-03 0010 Studies basic to heart
transplantation - Development and study of a heart
preservation chamber (dogs, sheep)
Functional properties of hemoglobin and
Investigation of hemoglobin S properties
Structural basis of nephron filtration
Structure and function of blood proteins
Hemoglobin and red cell system In
ROlHL-18725-03
process (human)
ROlHL-18737-03
ROlHL-18762-03
(dogs)
ROlHL-188 19-07
Light-scattering studies of the sickling
Human erythrocyte membrane structure
Post-traumatic pulmonary insufficiency
Chemical studies on sickle cell
hemoglobin (human)
ROlHL-18984-01 P50 effect on exercise limit in stable
angina (human)
ROlHL-19481-03 High-field NMR studies of respiratory
proteins (human, horse, fish, microbes)
ROlHL-19488-03 Picosecond laser studies of heme-
proteins
ROlHL-19532-01 Oxygen toxicity In the red cell (human)
POlHL-19737-02 0004 Cellular and molecular aspects of
respiratory physiology - Rapid reactions and erythrocyte
exchanges of blood during respiratory transport
ROlHL-20074-02 Structure and function of amidinated
human hemoglobin
ROlHL-20751-01 High speed liquid chromatography of
hemoglobins (human)
ROlHL-20961-02 Hemoglobin Y-chaIn genes-Evolution and
inducibility (monkeys, human)
POlHL-2 10 16-02 0003
hemoglobinopathies
and sickling
POlHL-21016-02 0015
hemoglobinopathies
Beth Israel (human)
ROlHL-21461-01
hemoprotelns
ROlHL-21483-01
of hemoglobin
ROIHL 21831-05
HEM
Sickle cell anemia and other
Role of non-S hemoglobin in gelation
Sickle cell anemia and other
EPR study of NO derivatives of Hb
Heme group protein interactions In
Electronic, thermodynamic and kinetics
Determining sequences from hemoglobin
messenger RNA (mice, chickens, rabbits)
ROlHL-22252-01 Synthesis of labeled hemes for protein
NMR studies
** ROlHL-2232501 Thermodynamics in respiratory protein
binding (human, trout)
ROlHL-23267-01 Rheology and kinetics of hemoglobin S
gelation (human)
** ROlHL-24048-01 Regulation of hemoglobin synthesis In
chick embryos
HEMOPROTEINS, HEMOGLOBIN,
METHEMOGIOBIN
SEE ALSO HEMOPROTEINS, METHEMOGLOBINEMIA
** ROlHL-13585-05 Heterogeneity of NADH methemoglobin
reductase (human)
ROlHL-13619-09 Microsomal electron transport In liver
and heart (human, mammals)
ROlHL-14127-16 Methemoglobinemia and antihypertensive
drugs (cats, mice, rats)
P60HL15157-07 0012 Comprehensive center for sickle
cell disease - Sickling and intracellular pH (human)
POIHL- 16833-04 0016 Hemoglobin and red cell system In
hemoglobinopathies - Calcium-lndlced membrane damage
in Hb SS disease (human, animals)
ROlHL-19463-02 Pathophysiology of acute renal failure
(rats)
P60HL-20985-01 0006 Northern California sickle cell
center - Antlslckling properties of imidoesters (human, rats)
HEMOPROTEINS, HEMOGLOBIN,
OXYHEMOGLOBIN
ROlHL-06950-17 Red cell metabolism (human,
vertebrates)
ROlHL-13412-17 Synthetic oxygen carriers
P60HL-15157-07 0012 Comprehensive center for sickle
cell disease - Sickling and intracellular pH (human)
ROlHL-16654-06
(human)
ROlHL-16860-05
hemoprotelns
ROlHL-17552-03
Regulation in developing erythroid cells
Mossbauer studies of respiratory
Sickling inhibition by chemical
modification of hemoglobin (human)
ROlHL-18710-02 Non-Invasive reflection oximetry in
peripheral tissue (dogs)
ROlHL-19324-02 Mechanisms of the inhibition of sickling
by DBA (human)
POlHL-19737-02 0006 Cellular and molecular aspects of
respiratory physiology - Tissue oxygenation and
mitochondrial respiratory activity (sheep)
ROlHL-20074-02 Structure and function of amidinated
human hemoglobin
ROlHL-20142-02 Functional studies of abnormal human
hemoglobins
POlHL-21016-02 0003 Sickle cell anemia and other
hemoglobinopathies - Role of non-S hemoglobin in gelatloi
and sickling
** R23HL-22621-01 Blood cell-mediated pulmonary (human)
ROlHL-22650-01 Regulatory mechanisms of erythropoietin
production (human, rats, mice)
ROlHL-22780-01 Factors modifying the reaction properties
of HgS (human)
HEMOPROTEINS, HEMOGLOBIN A2
P60HL-15158-07 0008 Comprehensive sickle cell center -
Core laboratory of the center
P60HL-15158-07 0016 Comprehensive sickle cell center -
Biochemical studies in sickle cell anemia (human)
P60HL-15158-07 0020 Comprehensive sickle cell center -
Immunochemical investigation of hemoglobin variants
(human)
P60HL-15160-07 0012 Center for sickle cell disease -
Core laboratories
P60HL-15162-07 0007 Comprehensive sickle cell center -
Core program-Demographic studies (human)
P60HL-15162-07 0018 Comprehensive sickle cell center -
Biochemical and genetic studies of sickle cell anemia
(human)
P60HL-15162-07 0020 Comprehensive sickle cell center ■
Biophysical studies of normal and sickle red cells (human)
P60HL-15168-07 0001 Comprehensive sickle cell disease
center - Screening program (human)
P50HL-15169-05 0019 Support for center for sickle cell
disease - Central screening and reference laboratory
P60HL-16005-05 9001 Comprehensive sickle cell center -
Core laboratory and counseling (human)
P60HL-16008-06 0020 Wayne State University
comprehensive sickle cell center - Genetic and physiological
studies of sickle cell anemia (human)
ROlHL-16646-05 Pathoblology of thromboembolic disorders
(human)
(confd)
^
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
**Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix lor investigator's name and grant number.
HEM
" POIHI 1683304 0001 Hemoglobin ind red cell system in
hemoilobinopelhies Motility, essociation and li|snd
bindini in hemoglobin Hydrogen exchange
•* POIHL 1683304 0002 Hemoglobin and led cell system in
hemoglobinopathies Polymeriiation and gel formation in
solutions ol hemoglobin A and S (human)
" POIHL 1683304 0003 Hemoglobin and red cell system in
hemoglobinopathies Oiygen binding curves and equilibria
(human)
" POIHL 16833 04 0004 Hemoglobin and red cell system in
hemoglobinopathies Purilication and fractionation ol
hemoglobin A and S (human)
** POIHL 1683304 0006 Hemoglobin and red cell system in
hemoglobinopathies Role of water in function ol
hemoglobin and myoglobin (human)
ROIHL'19646'03 An immunologic study of hemoglobin
variation in man
*• ROIHL 20393 03 Postsynthetic modifications ol
hemoglobin in diabetics (human)
ROlHL-2052003 Protein modification -The key to diabetic
sequelae (human, animal)
** ROIHL 2053903 Blood glucose, hemoglobin Ale. and
diabetic vascular disease (human)
** ROlHL-2092001 Control ol hemoglobin synthesis (baboon)
POIHL 2101602 0003 Sickle cell anemia and other
hemoglobinopathies Role of non-S hemoglobin in gelation
and sickling
POIHL'21016'02 0004 Sickle cell anemia and other
hemoglobinopathies Kinetics ol sickling
POlHL-21016-02 0009 Sickle cell anemia and other
hemoglobinopathies Nitrogen mustards and their potential
use as antisickling agent
ROIHL 2278001 Factors modifying the reaction properties
ol HgS (human)
HEMOPROTEINS, HEMOGLOBIN C
P60HL-1515807 0008 Comprehensive sickle cell center ■
Core laboratory ol the center
P60HL-1515807 0020 Comprehensive sickle cell center
Immunochemical investigation of hemoglobin variants
(human)
P60HL-1516207 0018 Comprehensive sickle cell center -
Biochemical and genetic studies of sickle cell anemia
(human)
P60HL15I6807 0001 Comprehensive sickle cell disease
center ■ Screening program (human)
P60HL15169-05 0019 Support for ceiiier for sickle cell
disease - Central screening and reference laboratory
R01HL16375-04 Investigation of hemoglobin S properties
(human)
** P01HL1683304 0006 Hemoglobin and red cell system in
hemoglobinopathies - Role of water in function ol
hemoglobin and myoglobin (human)
R01HL1964603 An immunologic study of hemoglobin
variation in man
POlHL-21016-02 0001 Sickle cell anemia and other
hemoglobinopathies - Supramolecular models of Hb S-
Mutational and EM approach
POlHL-21016-02 0014 Sickle cell anemia and other
hemoglobinopathies ■ Human hemoglobin mutants with
abnormal oxygen binding
HEMOPROTEINS, HEMOGLOBIN D
P60HL15158-07 0020 Comprehensive sickle cell center ■
Immunochemical investigation of hemoglobin variants
(human)
R01HLI6375-04 Investigation of hemoglobin S properties
(human)
HEMOPROTEINS, HEMOGLOBIN F
P60HL-15158-07 0004 Comprehensive sickle cell center -
Expression of abnormal hemoglobin synthesis in the
neonate and young child
P60HL15158-07 0016 Comprehensive sickle cell center -
Biochemical studies in sickle cell anemia (human)
P60HL-15158-07 0020 Comprehensive sickle cell center ■
Immunochemical investigation of hemoglobin variants
(human)
P60HL-15160-07 0012 Center for sickle cell disease -
Core laboratories
P60HL-15162-07 0007 Comprehensive sickle cell center -
Core program -Demographic studies (human)
P60HL-15162-07 0018 Comprehensive sickle cell center
Biochemical and genetic studies of sickle cell anemia
(human)
P60HL1516905 0019 Support for center for sickle cell
disease - Central screening and reference laboratory
P60HL1600505 0022 Comprehensive sickle cell center
Regulation ol erythropolesis in patients with sickle cell
anemia
P60HL-16008-06 0020 Wayne State University
comprehensive sickle cell center - Genetic and physiological
studies ol sickle cell anemia (human)
** POlHL-16851-04 0005 Human red cell membrane in
health and disease - Relation of hemoglobin species to
membrane properties (human)
•* ROlHL-20899-02 Cellular mechanisms of hemoglobin F
regulation (human)
** ROlHL-20905-02 Synthesis of fetal hemoglobin in erythroid
cells (sheep, human)
** ROlHL-20920-01 Control of hemoglobin synthesis (baboon)
** ROlHL-20922-02 Control of human fetal hemoglobin
synthesis
ROIHL 2093902
humans
ROIHL 22/80 01
ol HgS (human)
281
Regulation ol letil hemoglobin in
Factors modifying the reaction properties
HEMOPROTEINS, HEMOGLOBIN FETAL
SET ALSO HEMOPROIFINS, HEMOGLOBIN I
** ROIHL 02558 22 Structure lunction relationships in the
heme proteins (human, cattle)
** ROIHL 0516819 Inhomogencity ol hemoglobin types
(human)
ROIHL 1512507 Molecular pathology ol genetic disorders
in man
P60HL 1516007 0011 Center lor sickle cell disease
Study ol human sickle cells in an animal model (rats)
P60HL 15168 07 0001 Comprehensive sickle cell disease
center Screening program (human)
" P60HL-15999 05 0019 Miami comprehensive sickle cell
center Fetal-adult hemoglobin switch (mouse, monkey)
P60HL 15999-05 0021 Miami comprehensive sickle cell
center Diphosphonates Erythrocyte calcium loading.
maturation (human, chick embryo)
P60HL-16005 05 0013 Comprehensive sickle cell center ■
Study ol regulation of erythropolesis in vitro (human, rat.
hamster, rabbit)
P60HL16005-05 9001 Comprehensive sickle cell center -
Core laboratory and counseling (human)
POIHL 16851-04 0005 Human red cell membrane in
health and disease Relation of hemoglobin species to
membrane properties (human)
ROlHL-19532-01 Oxygen toxicity in the red cell (human)
R01HL19646-03 An immunologic study of hemoglobin
variation in man
ROIHL 20912-02 Control on non-alpha chain synthesis in
thassemic mice
ROlHL-20913-02 Cell culture studies of
hemoglobinopathies (human)
** ROlHL-20925-01 The acetylation of fetal hemoglobin
(human)
ROlHL-20939-02
humans
ROlHL-20961-02
Regulation of fetal hemoglobin in
Hemoglobin Y-chain genes -Evolution and
inducibility (monkeys, human)
** POlHL-2101602 0012 Sickle cell anemia and other
hemoglobinopathies ■ Stimulation of Hb F synthesis in a
permanent cell line
ROlHL-21831-05 Determining sequences from hemoglobin
messenger RNA (mice, chickens, rabbits)
ROlHL-23736-04 Sickle cell anemia and hemoglobin
synthesis (monkeys)
HEMOPROTEINS, HEMOGLOBIN H
P60HL-20985-01 0005 Northern California sickle cell
center - Molecular mechanism of alpha thalassemia -
Relation to sickle cell anemia (human)
POlHL-210 16-02 0014 Sickle cell anemia and other
hemoglobinopathies - Human hemoglobin mutants with
abnormal oxygen binding
HEMOPROTEINS, HEMOGLOBIN S
NOlHB-62962-02 Red cell distributions in cyanate-treated
blood (human, sheep)
ROlHL-05556-19 Proteins, lipoproteins -Structure and
reactivity (chicken, human, diving mammals)
ROlHL-05791-18 Structure and lunction in hemoglobins
(human)
POlHL-06285-18 0215 Cardiovascular-respiratory
physiology and biochemistry - Conformation of biopolymers
** ROlHL-07451-16 Hemoglobin S gelation and hemoglobin
allostery (human)
ROlHL-10383-12 Physical-chemical studies of hemoglobins
and erythrocyte (human)
** ROlHL-12256-15 Polymerization of sickle-cell hemoglobin
(human)
P60HL-151 57-07 0009 Comprehensive center for sickle
cell disease - Red cell membrane alterations during
sickling (human)
P60HL-151 57-07 0011 Comprehensive center for sickle
cell disease - Development of specific anti-sickling
compound (human)
** P60HL-151 57-07 0012 Comprehensive center for sickle
cell disease - Sickling and intracellular pH (human)
P60HL-15157-07 0018 Comprehensive center for sickle
cell disease - Red blood cell membrane physiology in sickle
cell anemia (human)
P60HL-151 58-07 0004 Comprehensive sickle cell center -
Expression of abnormal hemoglobin synthesis in the
neonate and young child
P60HL-151 58-07 0008 Comprehensive sickle cell center -
Core laboratory of the center
P60HL-15158-07 0014 Comprehensive sickle cell center -
Mechanism of sickling in human and deer hemoglobins
P60HL-151 58-07 0016 Comprehensive sickle cell center -
Biochemical studies in sickle cell anemia (human)
P60HL-15158-07 0020 Comprehensive sickle cell center -
Immunochemical investigation of hemoglobin variants
(human)
** P60HL-15160-O7 0008 Center for sickle cell disease -
Isocyanate derivatives and hemoglobin S association
(human, rat)
P60HL-151 60-07 0011 Center for sickle cell disease -
Study of human sickle cells in an animal model (rats)
HIM
P60HL 151600/ 0017 Center lor tickle cell diMiM
Core laboratories
* P60HI 15162 0/ 001/ Comprehensive sickle cell center
Hemoglobin, erythrocytes and sickle cell anemia (human.
rabbit)
P60HL 15162 07 0018 Comprehensive sickle cell center
Biochemical and genetic studies ol sickle cell anemia
(human)
P60HL 1516207 0020 Compreheniive sickle cell center
Biophysical studies ol normal and sickle red cells (human)
P60HL 151680/ 0001 Comprehensive sickle cell disease
center Screening program (human)
* P60HI 151680/ 0009 Comprehensive sickle cell disease
center Spin label study ol sickling (human)
* P60HL 15169 05 0018 Support for center lor sickle cell
disease Studies on sickle cell disease (human, rats.
dogs)
P60HL 15169 05 0019 Support lor center lor sickle cell
disease Central screening and relerence laboratory
" ROIHL 15293 07 Sickle cell hemoglobin Interactions and
aggregation (human)
ROIHL 15793-06 Molecular aspects ol erythrocyte
membrane resealing (human)
P60HL- 15999-05 0004 Miami comprehensive sickle cell
center Education, screening and counseling
P60HL 1599905 0014 Miami comprehensive sickle cell
center Biochemical and morphological parameters ol
sickle cells (human)
•* P60HL 1600505 0015 Comprehensive sickle cell center -
Molecular basis for the sickling phenomenon
P60HL 16005-05 9001 Comprehensive sickle cell center -
Core laboratory and counseling (human)
P60HL- 16008-06 0016 Wayne State University
comprehensive sickle cell center Red blood cell glycolysis
in sickle cell patients
" P60HL-16008-06 0017 Wayne State University
comprehensive sickle cell center Oxygen transport kinetics
of pre- and postsickling cells (human)
" P60HL-16008-06 0018 Wayne State University
comprehensive sickle cell center Hemoglobin S and RBC
membranes -Pathogenesis of irreversibly sickled cells
" ROlHL-16375-04 Investigation of hemoglobin S properties
(human)
** ROlHL-16654-06 Regulation in developing erythroid cells
(human)
** POlHL-16833-04 0001 Hemoglobin and red cell system in
hemoglobinopathies - Motility, association and ligand
binding in hemoglobin-Hydrogen exchange
** POIHL- 16833-04 0002 Hemoglobin and red cell system in
hemoglobinopathies Polymerization and gel formation in
solutions of hemoglobin A and S (human)
" POlHL-16833-04 0003 Hemoglobin and red cell system in
hemoglobinopathies - Oxygen binding curves and equilibria
(human)
POIHL 16833-04 0004
hemoglobinopathies
Hemoglobin and red cell system in
Purification and fractionation of
hemoglobin A and S (human)
POlHL-16833-04 0006 Hemoglobin and red cell system in
hemoglobinopathies - Role of water in function of
hemoglobin and myoglobin (human)
POlHL-16833-04 0014 Hemoglobin and red cell system in
hemoglobinopathies - Erythrocyte membrane damage in Hb
SS disease (human)
POlHL-16833-04 0017
hemoglobinopathies
effect (human)
POlHL-16851-04 0005
health and disease
Hemoglobin and red cell system in
Sulfhydryl group blockade antisickling
Human red cell membrane in
Relation of hemoglobin species to
membrane properties (human)
ROlHL-1692705 Structure and function of normal and
abnormal hemoglobin (human)
ROlHL-17494-07 Mechanism of liqand binding to
hemoglobin (human)
ROlHL-17552-03 Sickling inhibition by chemical
modification of hemoglobin (human)
POIHL- 18208-04 0005 Center for the study of blood cell
rheology - RBC deformability and capillary flow
interrelations (human, mice)
ROlHL-18818-04 Stereochemical mechanism of sickling of
hemoglobin S (human)
ROIHL 18819-07 Chemical studies on sickle cell
hemoglobin (human)
ROlHL-19324-02
by DBA (human)
ROlHL-1964603
Mechanisms of the inhibition of sickling
An immunologic study of hemoglobin
variation in man
ROlHL-20074-02 Structure and function of amidinated
human hemoglobin
ROlHL-20750-01 Studies in sickle cell disease (human)
P60HL-20985-01 0003 Northern California sickle cell
center - Kinetics of sickling and clinical manifestations in
sickling disorders (human)
POlHL-21016-02 Sickle cell anemia and other
hemoglobinopathies
POlHL-21016-02 0001 Sickle cell anemia and other
hemoglobinopathies - Supramolecular models of Hb S-
Mutational and EM approach
POlHL-21016-02 0002 Sickle cell anemia and other
hemoglobinopathies - Molecular events proceeding gelation
of Hb S
(contd)
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
**0nented significantly to above subject.
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
HEM
POlHL-21016-02 0003
hemoglobinopathies
and sickling
POlHL-21016-02 0004
hemoglobinopathies
POlHL-21016-02 0005
hemoglobinopathies
Sickle cell anemia and other
Role of non-S hemoglobin in gelation
Sickle cell anemia and other
Kinetics of sickling
Sickle cell anemia and other
Ligand kinetics in normal and Hb S
containing erythrocytes (human)
P01HL-210ie-02 0006 Sickle cell anemia and other
hemoglobinopathies - Analysis of the oxygen dissociation
curve of Hb S-containing red cells
POlHL-21016-02 0008 Sickle cell anemia and other
hemoglobinopathies - The clinical variations of sickle cell
anemia
POlHL-21016'02 0009 Sickle cell anemia and other
hemoglobinopathies - Nitrogen mustards and their potential
use as antisickling agent
POlHL-2101602 0010 Sickle cell anemia and other
hemoglobinopathies - Alkylureas as potential antisickling
agents
POlHL-21016-02 0014 Sickle cell anemia and other
hemoglobinopathies - Human hemoglobin mutants with
abnormal oxygen binding
POlHL-2101602 0017 Sickle cell anemia and other
hemoglobinopathies - The hereditary clinic core
ROlHL-2109602 Sickle cell crisis-Role of the erythrocyte
membrane (human)
R23HL-21129-02 The antisickling effects of imidoesters
ROlHL-2146901 Active transport and effect of CAOO in
sickle cell (human)
ROlHL-21757-01 Elastin structure-DNA breathing-
Hemoglobin S gelation
POlHL-22163-01 0001 Surface thrombogenesis-
Mechanisms and prevention - Initial blood protein and
platelet interactions with biomaterials (baboons)
ROlHL-22325-01 Thermodynamics in respiratory protein
binding (human, trout)
ROlHL-22654-01 Molecular structure of sickle cell fibers
(human)
' ROlHL-22780-01
of HgS (human)
' ROlHL-23267-01
gelation (human)
> ROlHL-23736-04
Factors modifying the reaction properties
Rheology and kinetics of hemoglobin S
Sickle cell anemia and hemoglobin
synthesis (monkeys)
HEMOPROTEINS, HEMOGLOBINOPATHIES
SEE ALSO HEMOPROTEINS, HEMOGLOBIN C
SEE ALSO HEMOPROTEINS, HEMOGLOBIN D
SEE ALSO HEMOPROTEINS, HEMOGLOBIN H
SEE ALSO METABOLIC DISORDERS (INBORN), PORPHYRIA
** ROlHL-02558-22 Structure-function relationships in the
heme proteins (human, cattle)
** ROlHL-02799-22 Abnormal hemoglobins (human)
** ROlHL-05168-19 Inhomogencity of hemoglobin types
(human)
ROlHL-0555619 Proteins, lipoproteins-Structure and
reactivity (chicken, human, diving mammals)
** ROlHL-14131-18 Abnormal hemoglobin syndromes
(human)
P60HL-15157-07 0001 Comprehensive center for sickle
cell disease - Screening program (human)
** P60HL-15158-07 0016 Comprehensive sickle cell center •
Biochemical studies in sickle cell anemia (human)
P60HL-15158-07 0020 Comprehensive sickle cell center -
Immunochemical investigation of hemoglobin variants
(human)
P60HL-15160-07 0003 Center for sickle cell disease ■
Genetic counseling in hemoglobinopathies-Dimensions,
effectiveness
** P60HL-15160-07 0013 Center for sickle cell disease ■
Immunochemical diagnosis of hemoglobinopathies (infants)
P60HL-15162-07 0007 Comprehensive sickle cell center ■
Core program-Demographic studies (human)
** P60HL-15168-07 0001 Comprehensive sickle cell disease
center ■ Screening program (human)
P60HL-151 70-05 0006 Support for center for sickle cell
anemia - Pediatric services-Comprehensive clinic
P60HL15170-05 0007 Support for center for sickle cell
anemia - Pediatric services-Screening program
** P60HL-16005-05 9001 Comprehensive sickle cell center -
Core laboratory and counseling (human)
ROlHL-16022-05 Determinants of the ventilatory response
to hypoxia (goats, cats)
ROlHL-16093-05 Functional properties of hemoglobin and
erythrocytes
P01HL16833-04 Hemoglobin and red cell system in
hemoglobmopathies
P01HL15833-04 0001 Hemoglobin and red cell system in
hemoglobinopathies • Motility, association and ligand
binding in hemoglobin -Hydrogen exchange
POlHL-16833-04 0003 Hemoglobin and red cell system in
hemoglobinopathies - Oxygen binding curves and equilibria
M
(human)
POlHL-16833-04 0004
hemoglobinopathies
Hemoglobin and red cell system in
Purification and fractionation of
hemoglobin A and S (human)
POIHL- 16833-04 0006 Hemoglobin and red cell system in
hemoglobinopathies - Role of water in function of
hemoglobin and myoglobin (human)
POlHL-16833-04 0014 Hemoglobin and red cell system in
hemoglobinopathies - Erythrocyte membrane damage in Hb
SS disease (human)
282
POlHL-16833-04 0015 Hemoglobin and red cell system in
hemoglobinopathies - Stereochemistry of hemoglobins from
magnetic circular dichroism (human)
R01HL-17571-03 Study of membrane permeability by NMR
relaxation (human)
R01HL-17808-03 Effect of altered oxygen affinity on
oxygen transport (human, rats)
POlHL-18208-04 Center for the study of blood cell
rheology
ROlHL-18226-04 Mechanism of oxygen supply to tissue
(human, animals)
ROlHL-19255-03 Evaluation of diagnostic clinical
hemorrheology (human)
An Immunologic study of hemoglobin
Functional studies of abnormal human
ROlHL-19646-03
variation in man
R01HL-20142-a2
hemoglobins
ROlHL-20751-01 High speed liquid chromatography of
hemoglobins (human)
ROlHL-209 13-02 Cell culture studies of
hemoglobinopathies (human)
ROlHL-20922-02 Control of human fetal hemoglobin
synthesis
POlHL-210 16-02 Sickle cell anemia and other
hemoglobinopathies
POlHL-2101602 0001 Sickle cell anemia and other
hemoglobinopathies - Supramolecular models of Hb S-
Mutational and EM approach
Sickle cell anemia and other
Molecular events proceeding gelation
Sickle cell anemia and other
Role of non-S hemoglobin in gelation
POlHL-21016-02 0002
hemoglobinopathies
of Hb S
POlHL-21016-02 0003
hemoglobinopathies
and sickling
POlHL-21016-02 0004 Sickle cell anemia and other
hemoglobinopathies - Kinetics of sickling
P01HL21016-02 0005 Sickle cell anemia and other
hemoglobinopathies - Ligand kinetics in normal and Hb S
containing erythrocytes (human)
POlHL-21016-02 0006 Sickle cell anemia and other
hemoglobinopathies - Analysis of the oxygen dissociation
curve of Hb S-containing red cells
POlHL-2 10 16-02 0007 Sickle cell anemia and other
hemoglobinopathies - Cellular determinants of red cell
sickling
POlHL-21016-02 0008
hemoglobinopathies
anemia
POlHL-21016-02 0009
hemoglobinopathies
Sickle cell anemia and other
The clinical variations of sickle cell
Sickle cell anemia and other
Nitrogen mustards and their potential
use as antisickling agent
POlHL-21016-02 0012 Sickle cell anemia and other
hemoglobinopathies - Stimulation of Hb F synthesis in a
permanent cell line
POlHL-21016-02 0013 Sickle cell anemia and other
hemoglobinopathies - Microcirculatoiy response to sickle
cell treated with antisickling agents (rats)
POlHL-21016-02 0014 Sickle cell anemia and other
hemoglobinopathies - Human hemoglobin mutants with
abnormal oxygen binding
POlHL-210 16-02 0015 Sickle cell anemia and other
hemoglobinopathies - EPR study of NO derivatives of Hb
Beth Israel (human)
POlHL-21016-02 0016
hemoglobinopathies -
retinopathy (human)
POlHL-21016-02 0017
hemoglobinopathies -
POlHL-210 16-02 0018
hemoglobinopathies
microscopy
POlHL-210 16-02 0019
hemoglobinopathies
Sickle cell anemia and other
The treatment of sickle cell
Sickle cell anemia and other
The hereditary clinic core
Sickle cell anemia and other
Scanning and transmission electron
Sickle cell anemia and other
Administration core
ROlHL-22654-01 Molecular structure of sickle cell fibers
(human)
ROlHL-23267-01 Rheology and kinetics of hemoglobin S
gelation (human)
** P60HL-2328201 0001 Comprehensive hospital/community
sickle cell center - Fetoscopy for intrauterine diagnosis of
hemoglobinopathy (human, monkeys)
HEMOPROTEINS, HEMOGLOBINOPATHIES,
SICKLE CELL ANEMIA
SEE ALSO HEMOPROTEINS, HEMOGLOBIN S
** N01H8-22919-08 Hemoglobin carbamylation in the
treatment of sickle cell anemia (human, dogs)
** NOlHB-22922-08 Develop effective therapy for sickle cell
disease (human, dogs)
NOlHB-62962-02 Red cell distributions in cyanate-treated
blood (human, sheep)
Statistical coordinating center for sickle
Abnormal hemoglobins (human)
Inhomogencity of hemoglobin types
Kinetic studies of blood (human)
Formation and survival of red blood cells
NOlHB-72982-03
cell disease
ROlHL-02799-22
ROlHL-05168-19
(human)
ROlHL-06242-18
ROlHL-07449-17
(human)
ROlHL-10383-12 Physical-chemical studies of hemoglobins
and erythrocyte (human)
ROlHL-12524-10 Reaction of hemoglobin with ligands and
antibodies (human, carp)
HEM
* ROlHL-14131-18 Abnormal hemoglobin syndromes
(human)
ROlHL-14785-07 Ultrasonic scattering for tissue
characterization (dogs, cattle, human)
ROlHL-14820-07 Factors affecting physiology of biological
membranes (human)
t P60HL-15157-O7 Comprehensive center for sickle cell
disease
'* P60HL-15157-07 0001 Comprehensive center for sickle
cell disease - Screening program (human)
'* P60HL-15157-07 0002 Comprehensive center for sickle
cell disease - Central data bank and research file
" P60HL-15157-07 0003 Comprehensive center for sickle
cell disease - Public education
'* P60HL-15157-07 0009 Comprehensive center for sickle
cell disease - Red cell membrane alterations during
sickling (human)
•* P60HL-15157-07 0011 Comprehensive center for sickle
cell disease - Development of specific antisickling
compound (human)
•* P60HL-1 5 157-07 0012 Comprehensive center for sickle
cell disease - Sickling and intracellular pH (human)
** P60HL-15157-07 0018 Comprehensive center for sickle
cell disease - Red blood cell membrane physiology in sickle
cell anemia (human)
M P60HL-15158-07 Comprehensive sickle cell center
** P60HL-15158-07 0004 Comprehensive sickle cell center -
Expression of abnormal hemoglobin synthesis in the
neonate and young child
** P60HL-15158-07 0008 Comprehensive sickle cell center -
Core laboratory of the center
** P60HL-15158-07 0009 Comprehensive sickle cell center -
Counseling and social services
** P60HL-15158-07 0010 Comprehensive sickle cell center -
Tutorial service for sickle cell anemia patients
** P60HL151 58-07 0011 Comprehensive sickle cell center -
Clinical services -Adult patients
" P60HL-15158-07 0012 Comprehensive sickle cell center -
Clinical services-Pediatric patients
** P60HL-15158-07 0014 Comprehensive sickle cell center -
Mechanism of sickling in human and deer hemoglobins
P60HL-15158-07 0016 Comprehensive sickle cell center -
Biochemical studies in sickle cell anemia (human)
** P60HL-15158-07 0020 Comprehensive sickle cell center -
Immunochemical Investigation of hemoglobin variants
(human)
** P60HL-15158-07 0025 Comprehensive sickle cell center -
Cardiovascular evaluation of children with sickle cell
disease (human)
P60HL-15158-07 0027 Comprehensive sickle cell center -
Community advisory board-Nancy Cobb house
** P60HL-15158-07 0028 Comprehensive sickle cell center -
Education
M P60HL-15160-07 Center for sickle cell disease
" P60HL-15160-07 0003 Center for sickle cell disease -
Genetic counseling in hemoglobinopathies-Dimensions,
effectiveness
** P60HL-15160-07 0008 Center for sickle cell disease -
Isocyanate derivatives and hemoglobin S association
(human, rat)
** P60HL-15160-07 0009 Center for sickle cell disease -
Natural history of sickle cell disease (human)
** P60HL-15160-07 0011 Center for sickle cell disease -
Study of human sickle cells In an animal model (rats)
** P60HL-15160-07 0012 Center for sickle cell disease -
Core laboratories
** P60HL-15160-07 0013 Center for sickle cell disease -
Immunochemical diagnosis of hemoglobinopathies (infants)
** P60HL-15160-07 0014 Center for sickle cell disease •
Replacement therapy of opsonin deficiency in sickle cell
anemia (children)
" P60HL-15160-07 0015 Center for sickle cell disease -
Lung function abnormalities in sickle cell
hemoglobinopathies (human)
** P50HL-15160-07 0016 Center for sickle cell disease -
Kinin and plasmin system in sickle cell disease (human)
** P60HL-15160-07 0017 Center for sickle cell disease -
Demonstration-Education, screening, counseling, patient
care
M P60HL-15162-07 Comprehensive sickle cell center
** P60HL-15162-07 0001 Comprehensive sickle cell center -
Core program-Patient care
** P60HL-15162-07 0007 Comprehensive sickle cell center -
Core program-Demographic studies (human)
** P60HL-15162-07 0010 Comprehensive sickle cell center -
Core program-Community outreach and education program
** P60HL-15162-07 0011 Comprehensive sickle cell center -
Core program-Genetic counseling and diagnostic screening
** P60HL-15162-07 0017 Comprehensive sickle cell center -
Hemoglobin, erythrocytes and sickle cell anemia (human,
rabbit)
** P60HL-15162-07 0018 Comprehensive sickle cell center -
Biochemical and genetic studies of sickle cell anemia
(human)
** P60HL-15162-07 0019 Comprehensive sickle cell center -
RBC-Blood rheology in sickle cell anemia and related
disorders (human, animal)
** P60HL-15162-07 0020 Comprehensive sickle cell center -
Biophysical studies of normal and sickle red cells (human)
** P60HL-15162-07 0021 Comprehensive sickle cell center -
Pneumococcal vaccine in sickle cell disease (children)
M P60HL-15168-07 Comprehensive sickle cell disease center
(contd)
•Excludes routine methodokigy OR covers only general projects which preclude indexing at the specific level.
**Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number
HEM
" P60HL 1516807 0001 Comptghensive sickle cell disease
center Sctaening progiam (human)
** P60HI. Ibl68 07 0002 Compfchensive sickle cell disease
center Patient care
" P60HL 1516807 0003 Comprehensive sickle cell disease
center Sickle cell education and training piogiam
** P60HI 1516807 0005 Comprehensive sickle cell disease
center Ophthalmology (human, rabbits, monkeys)
** P60HL 1516807 0006 Comprehensive sickle cell disease
center Core center
** P60HL 1516807 0009 Comprehensive sickle ceil disease
center Spin label study of sickling (human)
** P60HL 15168 07 0010 Comprehensive sickle cell disease
center Sickle cell center project (children)
M P60HL 1516905 Support tor center tor sickle cell disease
*• P60HL 1516905 0009 Support lor center lor sickle cell
disease Infections in sickle cell anemia (human)
•* P60HL1516905 0012 Support tor center lor sickle cell
disease Evaluation ot the incidence of cholelithiasis in
sickle cell disease (human)
** P60HL 1516905 0014 Support for center for sickle cell
disease - Orthopaedic aspects of sickle cell disease
(human)
•* P60HL1516905 0015 Support for center for sickle cell
disease Pathophysiology of acute pulmonary infiltrates in
sickle cell disease (human)
** P60HL-1516905 0017 Support for center for sickle cell
disease - Study of the natural history of sickle cell disease
in the home
** P60HL-1516905 0018 Support for center for sickle cell
disease Studies on sickle cell disease (human, rats,
dogs)
** P60HL15169-05 0019 Support for center for sickle cell
disease ■ Central screening and reference laboratory
** P60HL15169-05 0021 Support for center for sickle cell
disease - Multidlsciplinary module system for education.
screening and counseling
M P60HL15170-05 Support for center for sickle cell anemia
** P60HL-1 5170-05 0001 Support for center for sickle cell
anemia - Adult clinical services
*• P60HL-1517005 0002 Support for center for sickle cell
anemia • Adult services -Testing programs
** P60HL1517005 0003 Support for center for sickle cell
anemia - Adult services -Educational programs
** P6OHL-15170-05 0006 Support for center for sickle cell
anemia ■ Pediatric services -Comprehensive clinic
** P60HL-15170-05 0007 Support for center for sickle cell
anemia ■ Pediatric services-Screening program
** P60HL-15170-05 0008 Support for center for sickle cell
anemia - Pediatric services-Education program
P60HL-15170-05 0017 Support for center for sickle cell
anemia - Control of hemoglobulin synthesis (human)
** P60HL-15170-05 0019 Support for center for sickle cell
anemia - Renal handling of uric acid in sickle cell anemia
(human)
** P60HL1517O-05 0023 Support for center for sickle cell
anemia - Comprehensive sickle cell clinic
** P60HL-151 70-05 0030 Support for center for sickle cell
anemia ■ Adult services -Counseling program
ROlHL-15293-07 SicKle cell hemoglobin- Interactions and
aggregation (human)
R01HL15722-06 Hemorrheology studies related to in vivo
blood flow (human)
M P60HL-1599606 Cincinnati comprehensive sickle cell
center
** P60HL-15996-06 0001 Cincinnati comprehensive sickle
cell center - Coagulation mechanisms in sickle cell disease
(human)
** P60HL1 5996-06 0003 Cincinnati comprehensive sickle
cell center - Prophylactic penicillin in treatment of sickle
cell anemia (human)
** P60HL-1 5996-06 0004 Cincinnati comprehensive sickle
cell center - School adjustment of sickle cell patients
P60HL15996-06 0005 Cincinnati comprehensive sickle
cell center - Factors precipitating crises (human)
" P60HL15996-06 0006 Cincinnati comprehensive sickle
cell center - Education
** P60HL-15996-06 0007 Cincinnati comprehensive sickle
cell center - Screening and counseling
** P60HL-15996-06 0008 Cincinnati comprehensive sickle
cell center ■ Patient care (children, adults)
** P60HL-15996-06 0009 Cincinnati comprehensive sickle
cell center - Insurance coverage of persons with sickle cell
trait and disease
** P60HL1599606 0010 Cincinnati comprehensive sickle
cell center - Whole blood viscosity in sickle cell anemia
(human)
M P60HL1 5999-05 Miami comprehensive sickle cell center
** P60HL-1599905 0004 Miami comprehensive sickle cell
center - Education, screening and counseling
** P60HL-1 5999-05 0005 Miami comprehensive sickle cell
center < Sickle cell clinic
** P60HL-15999-05 0008 Miami comprehensive sickle cell
center ■ Cyanate effect on host defense -Cellular and
humoral (human, guinea pig, rabbits)
** P50HL1 5999-05 0014 Miami comprehensive sickle cell
center - Biochemical and morphological parameters of
sickle cells (human)
" P60HL- 15999-05 0019 Miami comprehensive sickle cell
center - Fetal-adult hemoglobin switch (mouse, monkey)
383
P60HI 1S999 05 0020 Miami comprehensive sickle cell
center Deficiency in complement dependent humoral
immunity Sickle cell disease (human)
P60HL 1599905 0021 Miami comprehensive sickle cell
center Diphosphonates Erythrocyte calcium laading,
maturation (human, chick embryo)
P60HL 16005 05 Comprehensive sickle cell center
P60H1 16005 05 0001 Comprehensive sickle cell center
Demonstration Community service component
P60HL 16005 05 0013 Comprehensive sickle cell center
Study of regulation of erythropoiesis in vitro (human, rat,
hamster, rabbit)
P60HL 1600505 0015 Comprehensive sickle cell center
Molecular basis for the sickling phenomenon
P60HL 1600505 0018 Comprehensive sickle cell center
Comprehensive study Natural history of sickle cell disease
in adults (human)
P60HL 1600505 0019 Comprehensive sickle cell center
Handling of uric acid in sickle cell anemia (human)
P60HL-16005-05 0020 Comprehensive sickle cell center
Studies of the immunologic defect in sickle cell anemia
(human)
P60HL 1600505 0021 Comprehensive sickle cell center -
Management of pregnancy in sickle cell anemia (human)
' P60HL16005-05 0022 Comprehensive sickle cell center ■
Regulation of erythropoiesis in patients with sickle cell
anemia
' P60HL1600505 9001 Comprehensive sickle cell center ■
Core laboratory and counseling (human)
P60HL 16008-06 Wayne State University comprehensive
sickle cell center
' P60HL16008-06 0001 Wayne State University
comprehensive sickle cell center - Patient care system
(children, adults)
' P60HL-16008-06 0009 Wayne State University
comprehensive sickle cell center Natural history of sickle
cell anemia (human)
' P60HL-16008-06 0011 Wayne State University
comprehensive sickle cell center - Education, screening and
counseling
' P60HL-1600806 0012 Wayne State University
comprehensive sickle cell center - Central data
management-Computer system
* P50HL16008-06 0014 Wayne State University
comprehensive sickle cell center - Zinc and red blood cell
metabolism in sickle cell anemia (rats, human)
* P60HL-16008-06 0015 Wayne State University
comprehensive sickle cell center ■ Trace elements in sickle
cell disease (human)
* P60HL-16008-06 0016 Wayne State University
comprehensive sickle cell center ■ Red blood cell glycolysis
in sickle cell patients
* P60HL- 16008-06 0017 Wayne State University
comprehensive sickle cell center ■ Oxygen transport kinetics
of pre- and postsickling cells (human)
* P60HL-16008-06 0018 Wayne State University
comprehensive sickle cell center - Hemoglobin S and RBC
membranes-Pathogenesis of irreversibly sickled cells
* P60HL- 16008-06 0019 Wayne State University
comprehensive sickle cell center ■ Cell mediated immunity
in sickle cell anemia (human)
* P60HL-1600806 0020 Wayne State University
comprehensive sickle cell center - Genetic and physiological
studies of sickle cell anemia (human)
* ROlHL-16375-04 Investigation of hemoglobin S properties
(human)
ROlHL-16421-08 Determinants of RBC deformability and
capillary flow (human, mice)
* ROlHL-16580-04
cell disease
* R01HL16647-05
(human)
ROlHL-166 54-06
(human)
* POlHL-16833-04 0002 Hemoglobin and red cell system in
hemoglobinopathies - Polymerization and gel formation in
solutions of hemoglobin A and S (human)
* POlHL-16833-04 0008 Hemoglobin and red cell system in
hemoglobinopathies - Membrane associated phenomena in
SS disease
'* P01HL16833-04 0011
hemoglobinopathies
Mathematical models for studying sickle-
Studies on the control of sickle cell crisis
Regulation in developing erythroid cells
Hemoglobin and red cell system in
Relationship between hemoglobin and
RBC membrane in sickling cells (human, rats)
POlHL-16833-04 0014
hemoglobinopathies
SS disease (human)
POlHL-16833-04 0015
hemoglobinopathies
Hemoglobin and red cell system in
Erythrocyte membrane damage in Hb
Hemoglobin and red cell system in
Calcium-indiced membrane damage
in Hb SS disease (human, animals)
POlHL-16833-04 0017
hemoglobinopathies
effect (human)
POlHL-1685104 0005
health and disease
Hemoglobin and red cell system in
Sulfhydryl group blockade antisickling
Human red cell membrane in
Relation of hemoglobin species to
membrane properties (human)
POlHL-16851-04 0010 Human red cell membrane in
health and disease - Core facility-Hematology clinic
ROlHL-1755203 Sickling inhibition by chemical
modification of hemoglobin (human)
R0IHL18O48-04 Dynamics of artificial and biological
membranes (human)
Human erythrocyte membrane structure
Mechanisms of the inhibition of sickling
An immunologic study of hemoglobin
HEM
POIHL 18208 04 0005 Canttr lor Ih* study ol blood coll
(heology RBC deformability and capillary flow
interrelations (human, mice)
POIHL 18208 04 0006 Center for the study of blood cell
rheology Analysis of flow in arterioles and capillaries
(human)
ROIHl 18551 03 Spectrin, actin, lipid and red cell
membrane structure
ROIHI 18/2503 light scattering studies of the sickling
piocess (human)
ROIHI 1873703
ROIHL 1932402
by DBA (human)
ROIHL 19646 03
variation in man
POIHL 1973702 0005 Cellular and molecular aspects of
respiratory physiology Interaction of respiratory eichanges
and blood gas parameters (human, animals)
ROIHL 1997301 Non invasive sickled cell monitor
development (human)
ROIHL 20074 02 Structure and function of amidinated
human hemoglobin
ROlHL-20241 02 Shear and area moduli (or abnormal red
cell membranes (human)
ROlHL-20314-02 Host defense against S pheumoniae in
sickle cell disease (human)
ROIHL 20725 02 Mechanisms and cellular functions of ion
transport
ROIHL 20750-01 Studies in sickle cell disease (human)
ROIHL 2089902 Cellular mechanisms of hemoglobin F
regulation (human)
ROIHL 20905 02 Synthesis of fetal hemoglobin in erythroid
cells (sheep, human)
ROlHL-20912-02 Control on non alpha chain synthesis in
thassemic mice
' ROlHL-20913-02 Cell culture studies of
hemoglobinopathies (human)
ROlHL-20920-01 Control of hemoglobin synthesis (baboon)
ROlHL-20925-01 The acetylation of fetal hemoglobin
(human)
ROlHL-20961-02 Hemoglobin Ychain genes -Evolution and
inducibility (monkeys, human)
P60HL-20985-01 Northern California sickle cell center
' P60HL-2098501 0001 Northern California sickle cell
center ■ Sickle cell anemia quality assurance program
* P60HL-2098501 0002 Northern California sickle cell
center Immunization with polyvalent pneumococcal
polysaccharide vaccine (human)
' PeOHL-20985-01 0003 Northern California sickle cell
center - Kinetics of sickling and clinical manifestations in
sickling disorders (human)
* P60HL-20985-01 0004 Northern California sickle cell
center - Characterization of irreversibly sickled cells
(human)
* P60HL-20985-01 0005 Northern California sickle cell
center - Molecular mechanism of alpha thalassemia-
Relation to sickle cell anemia (human)
* P60HL-20985-01 0007 Northern California sickle cell
center - Immunohematologic abnormalities in sickle cell
anemia (human)
* P60HL-20985-01 0008 Northern California sickle cell
center - Demonstration community program-Patient
ambudsman
* P60HL-20985-01 0009 Northern California sickle cell
center - Patient services (children, adults)
* P60HL-20985-01 0010 Northern California sickle cell
center - Prenatal diagnosis of sickle cell anemia
* P60HL-20985-01 0011 Northern California sickle cell
center - SNMA community education program
I POlHL-21016-02 Sickle cell anemia and other
hemoglobinopathies
* POlHL-2101602 0001 Sickle cell anemia and other
hemoglobinopathies - Supramolecular models of Hb S-
Mutational and EM approach
* POlHL-2 10 16-02 0002 Sickle cell anemia and other
hemoglobinopathies - Molecular events proceeding gelation
of Hb S
* POlHL-21016-02 0003
hemoglobinopathies
and sickling
* POlHL-21016-02 0004
hemoglobinopathies
* POlHL-21016-02 0005
hemoglobinopathies
Sickle cell anemia and other
Role of non-S hemoglobin in gelation
Sickle cell anemia and other
Kinetics of sickling
Sickle cell anemia and other
Ligand kinetics in normal and Hb S
containing erythrocytes (human)
POlHL-21016-02 0006 Sickle cell anemia and other
hemoglobinopathies - Analysis of the oxygen dissociation
curve of Hb Scontaining red cells
POlHL-2101602 0007 Sickle cell anemia and other
hemoglobinopathies - Cellular determinants of red cell
sickling
POlHL-210 16-02 0008
hemoglobinopathies
anemia
POlHL-21016-02 0009
hemoglobinopathies
Sickle cell anemia and other
The clinical variations of sickle cell
Sickle cell anemia and other
Nitrogen mustards and their potential
use as antisickling agent
POlHL-21016-02 0010 Sickle cell anemia and other
hemoglobinopathies - Alkylureas as potential antisickling
agents
(contd)
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
**0riented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
HEM
" POlHL-21016-02 0011 Sickle cell anemia and other
hemoglobinopathies - Metabolic effects of anti-sickling
agents (hamsters)
** PDlHL-21016-02 0013 Sickle cell anemia and other
hemoglobinopathies - Microcirculatory response to sickle
cell treated with anti-sickling agents (rats)
** POlHL-21016-02 0014 Sickle cell anemia and other
hemoglobinopathies ■ Human hemoglobin mutants with
abnormal oxygen binding
** POlHL-21016-02 0015 Sickle cell anemia and other
hemoglobinopathies - EPR study of NO derivatives of Hb
Beth Israel (human)
** POlHL-2 1016-02 0016 Sickle cell anemia and other
hemoglobinopathies ■ The treatment of sickle cell
retinopathy (human)
** POlHL-21016-02 0017 Sickle cell anemia and other
hemoglobinopathies - The hereditary clinic core
** POlHL-21016-02 0018 Sickle cell anemia and other
hemoglobinopathies - Scanning and transmission electron
microscopy
** POlHL-21016-02 0019 Sickle cell anemia and other
hemoglobinopathies - Administration core
R01HL-21096-02 Sickle cell crisis-Role of the erythrocyte
membrane (human)
" R23HL-2 11 29-02 The antisickling effects of imidoesters
*• ROlHL-21469-01 Active transport and effect of CAOO in
sickle cell (human)
** R01HL-2278001 Factors modifying the reaction properties
of HgS (human)
ROlHL-23200-01 Isolation of CA binding proteins from
erythrocytes (human)
M P60HL-23282-01 Comprehensive hospital/community sickle
cell center
** P60HL-23282-01 0002 Comprehensive hospital/community
sickle cell center - Clinical evaluation of alternate
pathaway of compliment activation
** P60HL-23282-01 0003 Comprehensive hospital/community
sickle cell center ■ Treatment of sickle cell ulcers with
physical therapy and vitamin E (human)
" P60HL-23282-01 0004 Comprehensive hospital/community
sickle cell center Bacterial, viral and mycoplasmal
infections and sickle cell disease complications
** P60HL-23282-01 9001 Comprehensive hospital/community
sickle cell center ■ Core -Institutionalization of education,
screening and counseling
** P60HL-23282-01 9002 Comprehensive hospital/community
sickle cell center - Core-Model sickle cell service for
neighborhood health centers
** ROlHL-23736-04 Sickle cell anemia and hemoglobin
synthesis (monkeys)
HEMOPROTEINS, HEMOGLOBINOPATHIES,
SICKLE CELL CRISIS
** NOlHB-72916-02 Crisis and pain symptom prophylaxis by
oral zinc therapy (human)
ROlHL-12174-11 Ventilation/perfusion distribution in the
lung (human, mammals)
ROlHL-12256-15 Polymerization of sickle-cell hemoglobin
(human)
** ROlHL-14131-18 Abnormal hemoglobin syndromes
(human)
P60HL-15157-07 0018 Comprehensive center for sickle
cell disease ■ Red blood cell membrane physiology in sickle
cell anemia (human)
P60HL-15158-07 0011 Comprehensive sickle cell center -
Clinical services-Adult patients
P60HL-15160-07 Center for sickle cell disease
P60HL-15160-07 0009 Center for sickle cell disease -
Natural history of sickle cell disease (human)
P60HL-15160-07 0011 Center for sickle cell disease -
Study of human sickle cells in an animal model (rats)
P60HL-15160-07 0014 Center for sickle cell disease -
Replacement therapy of opsonin deficiency in sickle cell
anemia (children)
** P60HL-15160-07 0016 Center for sickle cell disease -
Kinin and plasmin system in sickle cell disease (human)
P60HL-15160-07 0017 Center for sickle cell disease -
Demonstration-Education, screening, counseling, patient
care
P60HL15168-07 0002 Comprehensive sickle cell disease
center ■ Patient care
P60HL-15I69-05 0009 Support for center for sickle cell
disease ■ Infections in sickle cell anemia (human)
P60HL-15169-05 0015 Support for center for sickle cell
disease - Pathophysiology of acute pulmonary infiltrates in
sickle cell disease (human)
** P60HL-15169-05 0017 Support for center for sickle cell
disease - Study of the natural history of sickle cell disease
in the home
P60HL-15170-05 0006 Support for center for sickle cell
anemia - Pediatric services -Comprehensive clinic
** P60HL15996-06 0001 Cincinnati comprehensive sickle
cell center - Coagulation mechanisms in sickle cell disease
(human)
P60HL- 15996-06 0003 Cincinnati comprehensive sickle
cell center • Prophylactic penicillin in treatment of sickle
cell anemia (human)
** P60HL- 15996-06 0005 Cincinnati comprehensive sickle
cell center - Factors precipitating crises (human)
** P60HL- 15996-06 0008 Cincinnati comprehensive sickle
cell center - Patient care (children, adults)
284
P60HL-15996-06 0010 Cincinnati comprehensive sickle
cell center ■ Whole blood viscosity in sickle cell anemia
(human)
P60HL16008-06 0009 Wayne State University
comprehensive sickle cell center - Natural history of sickle
cell anemia (human)
** P60HL-16008-06 0015 Wayne State University
comprehensive sickle cell center - Trace elements in sickle
cell disease (human)
ROlHL-16375-04 Investigation of hemoglobin S properties
(human)
ROlHL-16647-05 Studies on the control of sickle cell crisis
(human)
** POlHL-16833-04 0009 Hemoglobin and red cell system in
hemoglobinopathies - Rheological studies of sickled cells
(human)
ROlHL-18818-04 Stereochemical mechanism of sickling of
hemoglobin S (human)
** ROlHL-20750-01 Studies in sickle cell disease (human)
P60HL-2098501 0003 Northern California sickle cell
center - Kinetics of sickling and clinical manifestations in
sickling disorders (human)
P60HL-20985-01 0007 Northern California sickle cell
center - Immunohematologic abnormalities in sickle cell
anemia (human)
P60HL-20985-01 0008 Northern California sickle cell
center - Demonstration community program -Patient
ambudsman
P60HL-20985-01 0009 Northern California sickle cell
center ■ Patient services (children, adults)
** ROlHL-21096-02 Sickle cell crisis-Role of the erythrocyte
membrane (human)
P60HL-23282-01 0004 Comprehensive hospital/community
sickle cell center - Bacterial, viral and mycoplasmal
infections and sickle cell disease complications
HEMOPROTEINS, HEMOGLOBINOPATHIES,
SICKLING INHIBITORS
** NOlHB-22922-08 Develop effective therapy for sickle cell
disease (human, dogs)
** NOlHB-6296202 Red cell distributions In cyanatetreated
blood (human, sheep)
NOlHB-729 16-02 Crisis and pain symptom prophylaxis by
oral zinc therapy (human)
ROlHL-02799-22 Abnormal hemoglobins (human)
R01HL07451-16 Hemoglobin S gelation and hemoglobin
allostery (human)
ROlHL-10383-12 Physical-chemical studies of hemoglobins
and erythrocyte (human)
** ROlHL-12256-15 Polymerization of sickle-cell hemoglobin
(human)
** P60HL-15157-07 0011 Comprehensive center for sickle
cell disease - Development of specific anti-sickling
compound (human)
P60HL-1 5 157-07 0012 Comprehensive center for sickle
cell disease - Sickling and intracellular pH (human)
P60HL-15157-07 0018 Comprehensive center for sickle
cell disease - Red blood cell membrane physiology in sickle
cell anemia (human)
P60HL-1 5 158-07 0014 Comprehensive sickle cell center ■
Mechanism of sickling in human and deer hemoglobins
** P60HL-15160-07 0008 Center for sickle cell disease -
Isocyanate derivatives and hemoglobin S association
(human, rat)
P60HL-1516007 0011 Center for sickle cell disease -
Study of human sickle cells in an animal model (rats)
P60HL-15162-07 0020 Comprehensive sickle cell center -
Biophysical studies of normal and sickle red cells (human)
P60HL-15168-07 0009 Comprehensive sickle cell disease
center - Spin-label study of sickling (human)
P60HL-15168-07 0010 Comprehensive sickle cell disease
center - Sickle cell center project (children)
** P60HL-15169-05 0018 Support for center for sickle cell
disease - Studies on sickle cell disease (human, rats,
dogs)
** R01HL15293-07 Sickle cell hemoglobin-Interactions and
aggregation (human)
M P60HL-15999-05 Miami comprehensive sickle cell center
** P60HL-15999-05 0008 Miami comprehensive sickle cell
center - Cyanate effect on host defense -Cellular and
humoral (human, guinea pig, rabbits)
P60HL-15999-05 0020 Miami comprehensive sickle cell
center ■ Deficiency in complement-dependent humoral
immunity-Sickle cell disease (human)
P60HL-15999-05 0021 Miami comprehensive sickle cell
center - Diphosphonates-Erythrocyte calcium loading,
maturation (human, chick embryo)
P60HL16005-05 0015 Comprehensive sickle cell center ■
Molecular basis for the sickling phenomenon
** P60HL16008-06 0014 Wayne State University
comprehensive sickle cell center - Zinc and red blood cell
metabolism in sickle cell anemia (rats, human)
P60HL-16008-06 0015 Wayne State University
comprehensive sickle cell center - Trace elements in sickle
cell disease (human)
P60HL-16008-06 0017 Wayne State University
comprehensive sickle cell center • Oxygen transport kinetics
of pre- and post-sickling cells (human)
R01HL16375-04 Investigation of hemoglobin S properties
(human)
** R01HL16654-06 Regulation in developing erythrold cells
(human)
HEM
M POlHL-16833-04 Hemoglobin and red cell system In
hemoglobinopathies
POlHL-1683304 0001 Hemoglobin and red cell system In
hemoglobinopathies - Motility, association and llgand
binding in hemoglobin-Hydrogen exchange
POlHL-16833-04 0003 Hemoglobin and red cell system In
hemoglobinopathies - Oxygen binding curves and equilibria
(human)
POlHL'16833-04 0009 Hemoglobin and red cell system In
hemoglobinopathies - Rheological studies of sickled cells
(human)
POIHL- 16833-04 0011 Hemoglobin and red cell system in
hemoglobinopathies - Relationship between hemoglobin and
RBC membrane in sickling cells (human, rats)
POlHL'16833-04 0015 Hemoglobin and red cell system In
hemoglobinopathies - Stereochemistry of hemoglobins from
magnetic circular dichroism (human)
" POlHL-16833-04 0017 Hemoglobin and red cell system in
hemoglobinopathies - Sulfhydryl group blockade antisickling
effect (human)
** ROIHL- 17552-03 Sickling inhibition by chemical
modification of hemoglobin (human)
ROIHL- 18725-03 Light-scattering studies of the sickling
process (human)
** ROlHL-18818-04 Stereochemical mechanism of sickling of
hemoglobin S (human)
** ROlHL-18819-07 Chemical studies on sickle cell
hemoglobin (human)
** R01HL19324-02 Mechanisms of the Inhibition of sickling
by DBA (human)
P60HL-20985-01 0003 Northern California sickle cell
center - Kinetics of sickling and clinical manifestations In
sickling disorders (human)
POlHL-2 10 16-02 0001 Sickle cell anemia and other
hemoglobinopathies - Supramolecular models of Hb S-
Mutational and EM approach
** POlHL-21016-02 0004 Sickle cell anemia and other
hemoglobinopathies - Kinetics of sickling
POlHL-2 10 16-02 0005 Sickle cell anemia and other
hemoglobinopathies - Llgand kinetics in normal and Hb S
containing erythrocytes (human)
** POlHL-2101602 0008 Sickle cell anemia and other
hemoglobinopathies - The clinical variations of sickle cell
anemia
** POlHL-21016-02 0009 Sickle cell anemia and other
hemoglobinopathies - Nitrogen mustards and their potential
use as antisickling agent
** POlHL-21016-02 0010 Sickle cell anemia and other
hemoglobinopathies - Alkylureas as potential anti-sickling
agents
** POlHL-2101602 0011 Sickle cell anemia and other
hemoglobinopathies - Metabolic effects of antisickling
agents (hamsters)
" POlHL-21016-02 0013 Sickle cell anemia and other
hemoglobinopathies - Microcirculatory response to sickle
cell treated with anti-sickling agents (rats)
** R23HL-21 129-02 The antisickling effects of imidoesters
ROlHL-21757-01 Elastin structure-DNA breathing-
Hemoglobin S gelation
ROlHL-22654-01 Molecular structure of sickle cell fibers
(human)
** R01HL-22780-01 Factors modifying the reaction properties
of HgS (human)
HEMOPROTEINS, HEMOGLOBINOPATHIES,
THALASSEMIA
SEE ALSO HEMOPROTEINS, HEMOGLOBIN A2
SEE ALSO HEMOPROTEINS. HEMOGLOBIN C
SEE ALSO HEMOPROTEINS, HEMOGLOBIN H
R01HL02799-22 Abnormal hemoglobins (human)
ROlHL-05168-19 Inhomogencity of hemoglobin types
(human)
ROlHL-06242-18 Kinetic studies of blood (human)
ROlHL-07047-16 Comparative study of cardiac conduction^
system (human, birds, mammals)
POlHL-10436-13 0008 A multidisclplinary study of
congenital heart disease - Physiologic consequences of
chronic hypoxemia (human)
ROlHL-15026-12 Quantitative genetic control of protein
synthesis (human, primates, mammals)
P60HL-1515707 0001 Comprehensive center for sickle
cell disease ■ Screening program (human)
P60HL-15158-07 0004 Comprehensive sickle cell center-
Expression of abnormal hemoglobin synthesis in the
neonate and young child
P60HL-15158-07 0008 Comprehensive sickle cell center -|
Core laboratory of the center
P60HL-15158-07 0009 Comprehensive sickle cell center -
Counseling and social services
P60HL-1515807 0011 Comprehensive sickle cell center ■
Clinical services-Adult patients
P60HL-1515807 0012 Comprehensive sickle cell center <
Clinical services -Pediatric patients
P60HL-15158-07 0016 Comprehensive sickle cell center-]
Biochemical studies in sickle cell anemia (human)
P60HL-15158-07 0020 Comprehensive sickle cell center ■
Immunochemical investigation of hemoglobin variants
(human)
P60HL15158-07 0025 Comprehensive sickle cell center-
Cardiovascular evaluation of children with sickle cell
disease (human)
P60HL-15160-07 0009 Center for sickle cell disease -
Natural history of sickle cell disease (human)
(contd)
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Onented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
HEM
P60HL 1^160 07 0011 Center lor sickle cell disease
Study of human sickle cells In an animal model (rats)
P60HL IbieOO? 0012 Center tor sickle cell disease
Core laboratories
P60HL 1516007 0013 Center lor sickle cell disease
Immunocliemical diagnosis ol hemoglobinopathies (inlants)
P60HL 1S162 07 0011 Comprehensive sickle cell center
Core program Genetic counseling and diagnostic screening
P60HI 15162 07 0018 Comprehensive sickle cell center
Biochemical and genetic studies ot sickle cell anemia
(human)
P60HL 15162 07 0019 Comprehensive sickle cell center
R6C Blood rheology in sickle cell anemia and related
disorders (human, animal)
P60HL 1516807 0001 Comprehensive sickle cell disease
center Screening program (human)
P60HL 1516807 0005 Comprehensive sickle cell disease
center Ophthalmology (human, rabbits, monkeys)
P60HL 1516807 0010 Comprehensive sickle cell disease
center Sickle cell center protect (children)
P60HL1516905 0017 Support for center lor sickle cell
disease Study ol the natural history ol sickle cell disease
in the home
' P60HL 1516905 0019 Support lor center lor sickle cell
disease Central screening and relerence laboratory
P60HL15170-05 0006 Support lor center lor sickle cell
anemia Pediatric services -Comprehensive clinic
P60HL 1600505 0018 Comprehensive sickle cell center
Comprehensive study-Natural history of sickle cell disease
in adults (human)
P60HL-16005-05 9001 Comprehensive sickle cell center •
Core laboratory and counseling (human)
POIHL- 1685 1-04 0005 Human red cell membrane in
health and disease - Relation ol hemoglobin species to
membrane properties (human)
* R01HL17465-04 Beta-thalassemia screening and genetic
counseling
ROlHL-1816304 Red cell membrane effects due to
oxidizing agents
POlHL-1820804 0005 Center for the study of blood cell
rheology - RBC deformability and capillary flow
interrelations (human, mice)
ROlHL-1964603 An immunologic study of hemoglobin
variation in man
* ROlHL-19898-03 Desferrioxamlne therapy in thalassemia
(dogs. rats, children)
* ROlHL-19946-03 Reduction ol iron overload in
thalassemia (children, rabbits, dogs, monkeys)
* ROlHL-19961-03 Management of hemosiderosis in
thalassemia (children, adults)
* ROlHL-20000-03 Iron overload in homozygous beta
thalassemia (human)
* ROlHL-20016-03 Chelator development for thalassemia
(human, mice, rats, dogs, monkeys)
ROlHL-20141-02 Biochemical approaches to management
ol iron overload (human, sheep, dogs)
ROlHL-20905-02 Synthesis ol letal hemoglobin in erythroid
cells (sheep, human)
* ROlHL-20912-02 Control on non-alpha chain synthesis in
Control of hemoglobin synthesis (baboon)
The acetylation of fetal hemoglobin
thassemic mice
ROlHL-20920-01
ROlHL-20925-01
(human)
ROlHL-20961-02 Hemoglobin Y-chain genes -Evolution and
inducibility (monkeys, human)
*• P60HL-20985-01 0005 Northern California sickle cell
center - Molecular mechanism of alpha thalassemia-
Relation to sickle cell anemia (human)
P60HL-20985-01 0007 Northern California sickle cell
center - Immunohematologic abnormalities in sickle cell
anemia (human)
P60HL-20985-01 0010 Northern California sickle cell
center - Prenatal diagnosis of sickle cell anemia
POlHL-21016-02 0014 Sickle cell anemia and other
hemoglobinopathies - Human hemoglobin mutants with
abnormal oxygen binding
** POlHL-21016-02 0016 Sickle cell anemia and other
hemoglobinopathies - The treatment of sickle cell
retinopathy (human)
** R23HL-2 1428-02 Expression of human globin in
thalassemia (human)
P60HL-23282-01 0002 Comprehensive hospital/community
sickle cell center - Clinical evaluation of alternate
pathaway of compliment activation
P60HL-23282-01 9001 Comprehensive hospital/community
sickle cell center - Core-lnstitutionalization of education,
screening and counseling
HEMOPROTEINS, HEMOGLOBINURIA,
PAROXYSMAL NOCTURNAL
** ROlHL-18012-04 Cellular defects in nocturnal
hemoglobinuria (human)
HEMOPROTEINS, METHEMOGLOBINEMIA
** ROlHL-13585-05 Heterogeneity of NADH methemoglobin
reductase (human)
** ROlHL-14127-16 Methemoglobinemia and antihypertensive
drugs (cats, mice, rats)
HEMOPROTEINS, MYOGLOBIN
SEE ALSO HEMOPROTEINS, MYOGLOBINOPATHIES
SEE ALSO HEMOPROTEINS, MYOGLOBINURIA
285
ROIHI 03290 71 Controls ol cardiac and vascular smooth
muscles (cats, rats, dogs)
ROIHI 05556 19 Proteins, lipoproteins Structure and
reactivity (chicken, human, diving mammals)
ROIHL 12526 09 Raman spectra ol heme proteins and
related molecules
ROIHL 13399 16 Heme protein structure and function
(human, horse, plants, bacteria)
Coboglobins Cobalt substituted myo and
Reactions ol oxygen with heme proteins
X ray photoelectron spectroscopy of heme
Structure and function ol respiratory
ROIHL 13531 06
hemoglobins
ROIHL 13581 11
R01HL13651 07
compounds
R01HL14508 10
hemoproteins
ROIHL 1468007 Specific enrichment of myoglobins lor
carbon 13 NMR (catacea)
POIHL 15194-07 0025 Pathophysiology of
cardiopulmonary dysfunction Myoglobinemia as an index
of myocardial ischemia and infarction
ROIHL 1528406 Hemoglobin and myoglobin kinetic
studies (human, animals)
ROIHL 15980-06 Reactions of hemeproteins and oxygen
(cattle)
POIHL 16833-04 0006 Hemoglobin and red cell system in
hemoglobinopathies Role of water in function of
hemoglobin and myoglobin (human)
ROIHL 1686005 Mossbauer studies ol respiratory
hemoproteins
P50HL 17669-04 0001 Ischeinic heart disease center
(SCOR) ■ Radioimmunoassays for CPK isoenzyme and
myoglobin (human, dog)
P50HL17669-04 0023 Ischemic heart disease center
(SCOR) - Patients with acute myocardial infarction and
myocardial ischemia (human)
' POlHL-17813-04 0007 Lung disease and the oxygenation
of blood and tissue - Studies on the function of myoglobin
(dogs)
ROlHL-18226-04 Mechanism of oxygen supply to tissue
(human, animals)
P01HL-18708-03 0007 Oxygen, energy and contractility in
cardiac tissue - Surfaces, energy requirements, and
contractile proteins ol cardiac cell in vitro
P01HL18708-03 0009 Oxygen, energy and contractility in
cardiac tissue - Regulation of oxygen utilization of cardiac
tissue (rats, rabbits)
* R01HL19299-03 Myoglobin and oxygen supply to heart
and muscle cells (rats, pigeons)
* R01HL19488-03 Picosecond laser studies of heme-
proteins
POlHL-19737-02 0009 Cellular and molecular aspects of
respiratory physiology ■ Regulation of tissue oxygen tension
and body carbon monoxide stores (human, dogs)
ROlHL-21461-01
hemoproteins
ROlHL-2148301
of hemoglobin
ROlHL-22252-01
NMR studies
ROlHL-22682-01
Heme group protein interactions in
Electronic, thermodynamic and kinetics
Synthesis of labeled hemes for protein
Structure and function of high density
lipoprotein (human, rat)
HEMOPROTEINS, MYOGLOBINOPATHIES
** ROlHL-2282101 A routine screening analysis for
myoglobinemia
HEMOPROTEINS, MYOGLOBINURIA
** POlHL-15194-07 0025 Pathophysiology of
cardiopulmonary dysfunction - Myoglobinemia as an index
of myocardial ischemia and infarction
HEMOPROTEINS BIOSYNTHESIS
ROlHL-02558-22 Structure-function relationships in the
heme proteins (human, cattle)
ROlHL-05168-19
(human)
Inhomogencity of hemoglobin types
Structure and function in hemoglobins
ROlHL-05791-18
(human)
ROlHL-15026-12 Quantitative genetic control of protein
synthesis (human, primates, mammals)
P60HL-15158-07 0016 Comprehensive sickle cell center -
Biochemical studies in sickle cell anemia (human)
P60HL-151 62-07 0018 Comprehensive sickle cell center -
Biochemical and genetic studies of sickle cell anemia
(human)
P60HL-151 68-07 0010 Comprehensive sickle cell disease
center - Sickle cell center project (children)
P60HL-151 70-05 0017 Support for center for sickle cell
anemia - Control of hemoglobulin synthesis (human)
P60HL-15999-05 0019 Miami comprehensive sickle cell
center - Fetal-adult hemoglobin switch (mouse, monkey)
P60HL- 159 99-05 0021 Miami comprehensive sickle cell
center - Oiphosphonates-Erythrocyte calcium loading,
maturation (human, chick embryo)
P60HL-16005-05 0013 Comprehensive sickle cell center -
Study of regulation of erythropoiesis in vitro (human, rat,
hamster, rabbit)
ROlHL-16375-04 Investigation of hemoglobin S properties
(human)
ROlHL-16445-05 Regulation of plasma protein
biosynthesis (rats, rabbits)
ROlHL-19324-02 Mechanisms of the inhibition of sickling
by DBA (human)
HEM
ROIHL 2039303 Postsynthetic modifications ol
hemoglobin in diabetics (human)
ROIHL 2089902 Cellular mechanisms ol hemoglobin F
regulation (human)
ROIHL 20905 02 Synthesis ol lelal hemoglobin in erythroid
cells (sheep, human)
ROIHL 20912 02 Control on non alpha chain synthesis in
thassemic mice
ROIHL 20913 02 Cell culture studies of
hemoglobinopathies (human)
Control ol hemoglobin synthesis (baboon)
Control ol human letal hemoglobin
The acetylation of fetal hemoglobin
Regulation ol letal hemoglobin in
ROIHL 2092001
ROIHL 2092202
synthesis
ROIHL 20925-01
(human)
" R01HL2093902
humans
RniHL-20961 02 Hemoglobin Y chain genes Evolution and
inducibility (monkeys, human)
P60HL-20985 01 0006 Northern Calilornia sickle cell
center Antisickling properties of imidoesters (human, rats)
" POIHL 21016 02 0012 Sickle cell anemia and other
hemoglobinopathies Stimulation of Hb F synthesis in a
permanent cell line
" ROIHL 23736 04 Sickle cell anemia and hemoglobin
synthesis (monkeys)
** ROIHL 24048-01 Regulation of hemoglobin synthesis in
chick embryos
HEMOPROTEINS METABOLISM
SEE ALSO HEMOPROTEINS BIOSYNTHESIS
SEE ALSO IRON METABOLISM
ROlHL-02799-22 Abnormal hemoglobins (human)
** R01HL0695017 Red cell metabolism (human,
vertebrates)
ROIHL 12944-09 Enzymatic and biochemical studies on
blood cells (human)
ROlHL-19933-02 Membrane and red cell dystunction.in
hemolytic anemia (human)
ROIHL 20939-02 Regulation of fetal hemoglobin in
humans
P60HL-20985-01 0006 Northern California sickle cell
center - Antisickling properties of imidoesters (human, rats)
** ROlHL-22780-01 Factors modifying the reaction properties
of HgS (human)
HEMOPROTEINS STRUCTURE
** ROlHL-02558-22 Structure-function relationships in the
heme proteins (human, cattle)
ROlHL-02799-22 Abnormal hemoglobins (human)
ROlHL-0516819 Inhomogencity ol hemoglobin types
(human)
** ROlHL-05556 19 Proteins, lipoproteins -Structure and
reactivity (chicken, human, diving mammals)
** ROlHL-05791-18 Structure and function in hemoglobins
(human)
** ROlHL-07451-16 Hemoglobin S gelation and hemoglobin
allostery (human)
R01HL10383-12 Physical-chemical studies of hemoglobins
and erythrocyte (human)
ROlHL-12256-15 Polymerization of sickle-cell hemoglobin
(human)
R01HL-12524-10 Reaction of hemoglobin with ligands and
antibodies (human, carp)
** ROlHL-12526-09 Raman spectra of heme proteins and
related molecules
ROlHL-13157-09 Molecular oxygen carriers-Synthesis,
structure, bonding
" ROlHL-13164-07 Interaction of the alpha and beta chains
of human hemoglobin
** ROlHL-13399-16 Heme protein structure and function
(human, horse, plants, bacteria)
** ROlHL-13531-06 Coboglobins-Cobalt substituted myo- and
hemoglobins
ROlHL-13581-11
•* R01HL-13651-07
compounds
** ROlHL-14508-10
hemoproteins
R01HL15125-07
in man
P60HL-15158-07 0008 Comprehensive sickle cell center -
Core laboratory of the center
** P60HL-15158-07 0014 Comprehensive sickle cell center •
Mechanism of sickling in human and deer hemoglobins
** P60HL-15158-07 0016 Comprehensive sickle cell center -
Biochemical studies in sickle cell anemia (human)
** P60HL-15158-07 0020 Comprehensive sickle cell center -
Immunochemical investigation of hemoglobin variants
(human)
P60HL-15160-07 0008 Center for sickle cell disease -
Isocyanate derivatives and hemoglobin S association
(human, rat)
P60HL-15160-07 0012 Center for sickle cell disease -
Core laboratories
•* P60HL-15162-07 0017 Comprehensive sickle cell center -
Hemoglobin, erythrocytes and sickle cell anemia (human,
rabbit)
P60HL-15162-07 0018 Comprehensive sickle cell center -
Biochemical and genetic studies of sickle cell anemia
(human)
P60HL-15168-07 0009 Comprehensive sickle cell disease
center - Spin-label study of sickling (human)
(contd)
Reactions of oxygen with heme proteins
X-ray photoelectron spectroscopy of heme
Structure and function of respiratory
Molecular pathology of genetic disorders
'Excludes routine methodotogy OR covers only general projects which preclude indexing at the specific level.
''Oriented significantly to above subject.
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
HEM
286
HEX
ROlHL-15284-06 Hemoglobin and myoglobin kinetic
studies (human, animals)
** ROlHL-1 5293-07 Sickle cell hemoglobin-Interactions and
aggregation (human)
R01HLlS4eO06 Molecular adaptation-Hemoglobin
systems of fish (marine)
** ROlHL-15627-06 X-ray and chemical studies of
metalloporphyrins
ROlHL-15980-06 Reactions of hemeproteins and oxygen
(cattle)
** P60HL-16005-05 0015 Comprehensive sickle cell center -
Molecular basis for the sickling phenomenon
P60HL-16005-05 9001 Comprehensive sickle cell center -
Core laboratory and counseling (human)
P60HL-1600806 0017 Wayne State University
comprehensive sickle cell center - Oxygen transport kinetics
of pre- and post-sickling cells (human)
ROlHL-16093-05 Functional properties of hemoglobin and
erythrocytes
** ROlHL-16601-05 Structure and function of blood proteins
(human, cattle)
ROlHL-16654-06 Regulation in developing etythroid cells
(human)
POlHL-16833-04 0015 Hemoglobin and red cell system in
hemoglobinopathies - Stereochemistry of hemoglobins from
magnetic circular dichroism (human)
ROlHL-16860-05 Mossbauer studies of respiratory
hemoproteins
" R01HL16891-05 The folding of hemoglobin
** ROlHL-16927-05 Structure and function of normal and
abnormal hemoglobin (human)
ROlHL-17494-07 Mechanism of liqand binding to
hemoglobin (human)
P50HL-17669-04 0002 Ischemic heart disease center
(SCOR) - Myocardial infarction sizing by radioimmunoassay
of cardiac myosin (dogs)
ROlHL-18309-04 Oxygen transport-Hemoglobins v»ith
modified hemes (horse)
** ROlHL-18634-03 Quarternary structure of erythro and
chlorocruorins (invertebrates)
R01HL-18gl8-04 Stereochemical mechanism of sickling of
hemoglobin S (human)
R01HL-188I9-07 Chemical studies on sickle cell
hemoglobin (human)
ROlHL-19646-03 An immunologic study of hemoglobin
variation in man
** ROlHL-20074-02 Structure and function of amidinated
human hemoglobin
" ROlHL-20142-02 Functional studies of abnormal human
hemoglobins
ROlHL-20393-03 Postsynthetic modifications of
hemoglobin In diabetics (human)
ROlHL-20520-03 Protein modification-The key to diabetic
sequelae (human, animal)
ROlHL-20750-01 Studies in sickle cell disease (human)
ROlHL-20905-02 Synthesis of fetal hemoglobin in erythroid
cells (sheep, human)
** ROlHL-209 12-02 Control on non-alpha chain synthesis in
thassemic mice
ROlHL-20925-01 The acetylation of fetal hemoglobin
(human)
** ROlHL-20961-02 Hemoglobin Y-chain genes -Evolution and
Inducibility (monkeys, human)
P60HL-20985-01 0003 Northern California sickle cell
center - Kinetics of sickling and clinical manifestations in
sickling disorders (human)
P60HL-20985-01 0005 Northern California sickle cell
center - Molecular mechanism of alpha thalassemia-
Relation to sickle cell anemia (human)
POlHL-21016-02 0001 Sickle cell anemia and other
hemoglobinopathies - Supramolecular models of Hb S-
Mutational and EM approach
POlHL-21016-02 0002 Sickle cell anemia and other
hemoglobinopathies ■ Molecular events proceeding gelation
of Hb S
** ROlHL-21483-01 Electronic, thermodynamic and kinetics
of hemoglobin
♦* ROlHL-22780-01
of HgS (human)
HEMORHEOLOGY
SEE BLOOD RHEOLOGY
HEMORRHAGE
SEE CARDIOVASCULAR DISORDERS, HEMORRHAGE
HEMORRHAGE, GASTROINTESTINAL
SEE GASTROIf^TESTINAL CIRCULATORY DISORDERS,
HEMORRHAGE, GASTROINTESTINAL
HEMORRHAGIC DISORDERS
SEE BLOOD AND RE DISORDERS, HEMORRHAGIC DISORDERS
HEMORRHAGIC FEVER
SEE VIRUS DISEASES, ARBOVIRUS, DENGUE
HEMORRHAGIC FEVER VIRUSES
SEE VIRUSES. ARBOVIRUSES, HEMORRHAGIC FEVER VIRUSES
HEMORRHAGIC SHOCK
SEE CARDIOVASCULAR DISORDERS, HEMORRAGIC SHOCK
HEMOSIDEROSIS
SEE IRON DISORDERS AND IMBALANCES, HEMOSIDEROSIS
Factors modifying the reaction properties
HEMOSTASIS
SEE BLOOD STASIS
HEMOSTATICS
SEE BLOOD COAGULATION, HEMOSTATICS
HEMOTOXINS
SEE BLOOD TOXICOLOGY, HEMOTOXINS
HEMP (INDIAN)
SEE ALKALOIDS, CANNABIS
HEPARAN SULFATE
SEE POLYSACCHARIDES, GLYC0SAMIN06LYCANS. HEPARAN
SULFATE
HEPARIN
SEE POLYSACCHARIDES, GLYCOSAMINOGLYCANS, HEPARIN
BETA-HEPARIN
SEE POLYSACCHARIDES, GLYCOSAMINOGLYCANS. DERMATAN
SULFATE
HEPARIN CLEARING FACTOR
SEE LIPASES, LIPOPROTEIN LIPASE
HEPARIN CO-FACTOR
SEE BLOOD COAGUUTION, HEPARIN CO-FACTOR
HEPARIN MONOSULFATE
SEE POLYSACCHARIDES, GLYCOSAMINOGLYCANS. HEPARAN
SULFATE
HEPARINASE
SEE POLYSACCHARIDE CO LYASES. HEPARINASE
HEPARITIN SULFATE
SEE POLYSACCHARIDES, GLYCOSAMINOGLYCANS, HEPARAN
SULFATE
HEPATIC CIRCULATION
SEE LIVER CIRCULATION
HEPATIC COMA
SEE LIVER DISORDERS. HEPATIC COMA-ENCEPHALOPATHY
HEPATIC ENCEPHALOPATHY
SEE LIVER DISORDERS, HEPATIC COMA-ENCEPHALOPATHY
HEPATITIS
SEE LIVER DISORDERS, HEPATITIS
HEPATITIS A
SEE LIVER DISORDERS. HEPATITIS VIRAL HUMAN
HEPATITIS A VIRUS (HAV)
SEE VIRUSES, HEPATITIS A VIRUS (HAV)
HEPATITIS B
SEE LIVER DISORDERS, HEPATITIS SERUM
HEPATITIS B ANTIGEN (HBAG)
SEE IMMUNOLOGY, ANTIGENS VIRAL, HEPATITIS B ANTIGEN
(HBAG)
HEPATITIS B VIRUS (HBV)
SEE VIRUSES, HEPATITIS B VIRUS (HBV)
HEPATITIS (HOMOLOGOUS) SERUM
SEE LIVER DISORDERS, HEPATITIS SERUM
HEPATITIS VACCINE, SERUM HEPATITIS
SEE VACCINES, VIRAL, HEPATITIS, SERUM
HEPATITIS VIRAL HUMAN
SEE LIVER DISORDERS, HEPATITIS VIRAL HUMAN
HEPATITIS VIRUSES
SEE VIRUSES, HEPATITIS
HEPATO-CEREBRO-RENAL SYNDROME
SEE METABOLIC DISORDERS INBORN, CEREBRO-HEPATO-
RENAL SYNDROME
HEPATOCUPREIN
SEE METALLOPROTEINS, CYTOCUPREINS
HEPATOLENTICULAR DEGENERATION
SEE METABOLIC DISORDERS INBORN, HEPATOLENTICULAR
DEGENERATION
HEPATOMA
SEE NEOPLASMS OF BILIARY TRACT, LIVER NEOPLASMS,
HEPATOMA
HEPATORENAL SYNDROME
SEE LIVER DISORDERS, HEPATORENAL SYNDROME
HEPATOTOXINS
SEE LIVER DISORDERS, TOXIC LIVER DISORDERS,
HEPATOTOXINS
HEREDITARY DISORDERS
SEE GENETIC DISORDERS (SEE ALSO APPROPRIATE
CONGENITAL ABNORMALITIES)
HEREDITARY DISORDERS, BLOOD (AND RE
SYSTEM)
SEE BLOOD AND RE DISORDERS CONGENITAL (HEREDITARY)
HEREDITARY DISORDERS, METABOLIC ERRORS
SEE METABOLIC DISORDERS INBORN
HEREDITY
SEE GENETICS
HERNIA, DIAPHRAGMATIC
SEE BODY CAVITY DISORDERS, DIAPHRAGMATIC HERNIA
HERPESVIRUS INFECTIONS
SEE VIRUS DISEASES, HERPESVIRUS
HERPESVIRUSES
SEE VIRUSES. HERPESVIRUSES
HETEROCHROMOSOME
SEE GENETICS. CHROMOSOMES, SEX CHROMOSOMES
HETEROCYCLICS
SEE CYCLICS, HETEROCYCLICS
HETEROKARYON
SEE CELL HYBRIDS, HETEROKARYON
HETEROTRANSPLANTATION
SEE TISSUE COMPATIBILITY-TRANSPLANT, TRANSPLANTATION
HETEROLOGOUS
HETEROZYGOTES
SEE GENETICS, GENOTYPES. HETEROZYGOTES
HUERISTICS (ARTIFICIAL INTELUGENCE)
SEE COMPUTER, ARTIFICIAL INTELLIGENCE, PAHERN
RECOGNITION AND CONTROL SYSTEMS
HEXOSAMINIDASE A AND B
SEE CARBOHYDRASES, HEXOSAMINIDASES
HEXOSAMINIDASES
SEE CARBOHYDRASES, HEXOSAMINIDASES
HEXOSANS, GALACTAN
ROIHL-19685-03 Pathogenesis of inflammation of the lung
(guinea pigs)
HEXOSANS, GLUCANS, DEXTRAN
POlHL-16851-04 0008 Human red cell membrane in
health and disease - Force balance in red cell interactions
(human)
Capillary transport of large molecules
ROlHL-18010-04
(dogs, sheep)
ROlHL-18590-03
(dogs, monkeys)
ROlHL-18607-03
Cerebral blood flow after cardiac arrest
Metabolic and drug studies on
experimental fat embolism (mice)
ROlHL-19203-03 Surgical approach to congenital heart
diseases (dogs, primates)
ROlHL-20337-02 Thromboembolic diseases (human)
R23HL-21050-02 Mechanisms of re-expansion pulmonary
edema (rabbits)
ROlHL-22435-02 Pulmonary alveolar-capillary permeability
characteristic (dogs)
HEXOSANS, GLUCANS, GLYCOGEN
SEE ALSO METABOLIC DISORDERS INBORN, GLYCOGENOSIS
POlHL-12373-10 0006 Cardiopulmonary physiology and
pathophysiology - Fatty acid metabolism-Regulation,
implications (human, mammals, birds)
POlHL-12373-10 0012 Cardiopulmonary physiology and
pathophysiology - Biochemistry of the sympathetic nervous
system (rats, rabbits, pigeons)
** ROlHL-13630-08 Control of glycogen synthesis in heart
(cattle)
ROlHL-15813-05 Cardiac anoxia-Protective effect of
carbohydrate (dogs)
ROlHL-19752-03 Phospholipid synthesis by fetal lung in
organ culture (rats)
ROlHL-20720-02 Myocardial protection during
cardiopulmonary bypass (dogs)
ROlHL-23161-01 0003 Biology of myocardial ischemia -
Phosphorylase coupling to myocardial sarcoplasmic
reticulum (dog)
HEXOSANS, GLUCANS, GLYCOGENOLYSIS
P50HL-14217-08 0057 Specialized center of research in
thrombosis - Pharmacology-Platelet biochemistry (human,
animal)
P50HL-14217-08 0059 Specialized center of research in
thrombosis - Energy metabolism and platelet function
(human)
P60HL-17269-04 0019 National heart and blood vessel
research and demonstration center - Sarcoplasmic
reticulum (dog, rabbit, hamster, cat)
ROlHL-17907-04 Brain regulation of cardiac arrhythmia
(pigs, cats, rats)
ROlHL-18239-03 Dietary fat composition and
prostaglandin synthesis (rats)
** ROlHL-18280-03 Regulation of cardiac contractility and
metabolism (rats)
ROlHL-20476-03 Effects of diabetes on cardiac
performance (rat)
** ROlHL-22064-02 Glycogen metabolism in anoxic diabetic
myocardium (rats)
ROlHL-22354-01 Alpha-adrenergic effects on heart
metabolism (rats)
** ROlHL-22828-01 Adenosine and catecholamine interaction
in the heart (rats)
(contd)
*E>d(ides routine melhodokigy OR covers only general projects which preclude indexing at the specific level.
"Onented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
^KSiS
HEX
** ROIHL 23161 01 0003 Biology ot myocsrdni ischemu
Phosphorylase coupling to myoocdial satcoplasmic
reticulum (dog)
ROIHL 23161 01 0004 Biology ol myocardial ischemia
Structure ol myotibrils and membranes in early ischemia
(dogs, rabbit, rodents)
HEXOSANS, LEVANS, INULIN
ROIHL 19463 02 Pathophysiology ot acute renal tallure
(rats)
HEXOSEDIPHOSPHATASE
SEE PHOSPHOMONOESTERASES. FRUCTOSE 1.6
OIPHOSPHATASE
HEXOSE MONOPHOSPHATE PATHWAY
SEE PENTOSE PATHWAYS, HEXOSE MONOPHOSPHATE
PATHWAY
HEXOSES
ROIHL 1656704 Oiflerentiation of the heaitcell
membrane (mice, chick)
** POIHL 16851-04 0006 Human red cell membrane in
health and disease Hexose transport and erythrocyte
membrane proteins (human)
HEXOSES, FRUCTOSE
P01HL0628518 0198 Cardiovascular respiratory
physiology and biochemistry Renal tubular secretion of
hydrogen ion (animals)
HEXOSES, GAIACTOSAMINES
ROlHL-23945-06 Pathologic effects on cells of modified
lipoproteins (rats, human)
HEXOSES, GAIACTOSAMINES, N-
ACETYLGALACTOSAMINE
ROIHL 1512507 Molecular pathology of genetic disorders
in man
ROlHL-17881-15 Biosynthesis and degradation of blood
group substances (human, animals)
HEXOSES, GLUCOGENESIS
SEE ALSO CARBOHYDRATES BIOSYNTHESIS
ROIHL 1581305 Cardiac anoxia-Protective effect of
carbohydrate (dogs)
HEXOSES, GLUCONEOGENESIS
SEE ALSO CARBOHYDRATES BIOSYNTHESIS,
GLYCONEOGENESIS
SEE ALSO KETONE BODIES
POlHL-0868215 0020 Regulation of the cardiovascular
system ■ Hepatic metabolic basis of shock (rat)
HEXOSES, GLUCOSAMINE
ROlHL-13885-08 0008 Cystic fibrosis and pulmonary
disease - Pseudomonas specific activation of alveolar
macrophages (human, rabbits)
ROlHL-21763-09 Heparin and heparan sulfate-Structure
and activity (beef, hog)
HEXOSES, GLUCOSE
SEE ALSO CARBOHYDRATE BALANCE, GLUCOSE TOLERANCE
SEE ALSO CARBOHYDRATES METABOLISM, GLUCOSE
METABOLISM
SEE ALSO CARBOHYDRATES TRANSPORT, GLUCOSE
TRANSPORT
SEE ALSO HEXOSES, GLUCOGENESIS
SEE ALSO HEXOSES, GLYCOLYSIS
ROlHL-02334-23 Micropuncture study of kidney function
(rats, animals)
ROlHL-05883-18 0002 Reflex control of resistance and
capacitance vessels - Adenosine, adenine nucleotides and
vascular smooth muscle (dog)
POlHL-0628518 0199 Cardiovascular-respiratory
physiology and biochemistry - Renal tubular reabsorption of
sodium chloride (hamsters, rabbits)
POlHL-0666417 0036 Cardiopulmonary function in
remediable vascular disease - In vitro studies on the
mechanism of ischemic damage to cells (rabbits)
** POlHL-06835-17 0022 Cardiovascular disease - Arterial
lipogenesis from glucose in the rat
POlHL-06835-17 0024 Cardiovascular disease - Studies
on the obese spontaneously hypertensive rat
POlHL-08899-14 0012 Tolerance to respiratory gases in
health and disease • High oxygen for normal brain
metabolism and circulation in man
POlHL-08899-14 0055 Tolerance to respiratory gases in
health and disease - Oxygen effects on organ functions-
Extension of tolerance
ROlHL-09489-13 Myocardial lipid metabolism and
regulation (rats)
POlHL-11310-12 0063 Mechanisms of cardiovascular
disease - Myocardial function, metabolism and cellular
integrity after heart surgery (dogs)
POlHL-12157-11 0051 Functions and mechanisms of cell
membrane ion transport Electron transport in the red cell
membrane (human, guinea pigs)
ROlHL-13193-09 Pathophysiology of post-traumatic and
shock states (rodents, dogs)
POlHL-14388-07 0219 Regulation of the circulation in
pathological states - Myocardial ischemia and infarction in
animals (dogs)
ROlHL-15813-05 Cardiac anoxia-Protective effect of
carbohydrate (dogs)
Cardiovascular and renal functions of
Limiting factors in oxygen uptake in the
287
ROIHI 15949 05 lipoprotein metabolism in relation to
atherosclerosis (human, baboons)
P50H1 17667 04 0040 Study of ischemic heart disease
Core biochemistry Cardiac metabolism (human)
ROIHL 1784704
marmots
ROIHL 17967 04
lung
ROIHL 18537 04 Regional blood flow after acute
myocardial injury (dogs)
ROIHL 1860604 Pathogenesis and measurement of
pulmonary edema (human, rabbits, dogs)
ROIHL 18647 03 Ischemic myocardial injury in cultured
heart cells (rats)
ROIHL 1919503 Hormonal regulation of lung function
(rats)
ROIHL 1998402 Blood pressure and immunogenetic
factors in the young (human)
ROIHL 2015903 Genetic epidemiology of precursors of
hypertension (human)
POlHL-2055202 0001 The development and regression of
cardiac hypertrophy Biochemical events in cardiac
hypertrophy (rats)
R01HL21140-01 Studies of pulmonay alveolar
macrophage function (rabbits)
ROlHL-21172 02 Regional oxygen consumption of heart
and other organs (animals)
R23HL-21393-01 Cardiac adaptation to aging and stress
(rats)
ROlHL-2250001 Conversion of choline to
phosphatidylcholine in lung (rabbits, pigs)
ROIHL 22569-02 Intestinal secretion-Capillary and tissue
forces (dogs, cats)
POlHL-22619-01 0010 Cellular mechanisms of heart
failure ■ Mitochondria in heart and smooth muscle (rabbits,
rats, dogs)
ROIHL 23618-01 Substrate metabolism in isolated
myocytes In shock (dogs, rats, guinea pigs)
HEXOSES, GLUCOSE, O-METHYL GLUCOSE
R01HL13029-09 Metabolic regulation of sugar transport
(pigeons, rats)
HEXOSES, GLUCOSE-6-PHOSPHATES
ROlHL-20393-03 Postsynthetic modifications of
hemoglobin in diabetics (human)
HEXOSES, GLYCOLYSIS
SEE ALSO PENTOSE PATHWAYS
SEE ALSO TRICARBOXYLIC ACIDS, KREBS CYCLE
ROIHL 13193-09 Pathophysiology of post-traumatic and
shock states (rodents, dogs)
ROlHL-1356706 Ion transport across cell membranes
(human)
P50HL14138-05 0015 Center for research on
atherosclerosis - Arterial wall-Intermediary metabolism,
enzyme activity and bioenergetics
P50HL142 17-08 0057 Specialized center of research in
thrombosis - Pharmacology -Platelet biochemistry (human,
animal)
P50HL- 142 17-08 0059 Specialized center of research in
thrombosis - Energy metabolism and platelet function
(human)
ROlHL-15013-07 Lung oxidative metabolism and energy
production (rodents, rabbits)
P50HL15061-07 0002 Response of lung to injury -
Oxidative metabolism, phospholipid synthesis, and response
to toxins (rats)
ROlHL-15622-05 Computer simulation in cardiology (rats,
dogs)
** P60HL- 160 08-06 0016 Wayne State University
comprehensive sickle cell center ■ Red blood cell glycolysis
In sickle cell patients
** P50HL-1766704 0012 Study of ischemic heart disease -
Biochemistry of normal and ischemic heart -Glycolysis (rats)
ROlHL-17729-04
(human)
** ROlHL-17976-18
enzymes (sheep)
" ROlHL-18206-04
deficient hearts (rats)
POlHL-18708-03 0007 Oxygen, energy and contractility in
cardiac tissue - Surfaces, energy requirements, and
contractile proteins of cardiac cell in vitro
ROlHL-19378-03 Relation of mitochondrial changes to
cardiac failure (dogs, rats)
ROlHL-20484-03 Effects of diabetes on cardiac function
and metabolism (rats)
ROlHL-20566-02 Lactate metabolism in the lung (rats)
P60HL-20985-01 0006 Northern California sickle cell
center - Antisickling properties of imidoesters (human, rats)
ROlHL-21381-02 Amino acid metabolism in normal and
hypoxic myocardium (rabbits)
R23HL-21393-01 Cardiac adaptation to aging and stress
(rats)
ROlHL-22101-02 Hormone-substrate interaction in diabetic
myocyte (dogs, rats)
ROlHL-22333-01 Cellular basis of small airways function
(rats)
POlHL-22619-01 0010 Cellular mechanisms of heart
failure - Mitochondria in heart and smooth muscle (rabbits,
rats, dogs)
Stimulus-response coupling in platelets
Chemical agents and heart glycolytic
Regulation of metabolism in oxygen
HIS
ROIHL 2315901 Regulition ol lipogenext by
polyunsaturated fats (cats, chicks)
ROIHL 23205 01 Contraction ol pulmonary vascular
smooth muscle (cat)
HEXOSES, GLYCOLYSIS ANAEROBIC
P50HL 1/670 04 0023 Study of ischemic heart disease
Energy metabolism in acute myocardial ischemic injucy
(dogs)
ROIHL 18143 03 Surgery and pulmonary tissue alterationi
(dogs, rats, human)
ROIHL 22064 02 Glycogen metabolism in anoxic diabetic
myocardium (rats)
ROIHL 2316601 Pathology of mrtochondria in ischemic
myocardium (rats, cattle)
HEXOSES, GLYCOLYSIS ANAEROBIC, E-M
PATHWAY
ROIHL 19324 02 Mechanisms of the inhibition of sickling
by DBA (human)
HEXOSES, MANNOSE
ROIHL- 17 783-04 Complex carbohydrates Structure,
function, synthesis (swine)
HGPRT
SEE GLYCOSYLTRANSFERASES. IMPPYROPHOSPHATE
PHOSPHORIBOSYLTRANSFERASE
HIATUS HERNIA
SEE BODY CAVITY DISORDERS. DIAPHRAGMATIC HERNIA
HIBERNATION
SEE ENVIRONMENT, ADAPTATION. HIBERNATION
HIGH-DENSITY LIPOPROTEIN DEFICIENCY
FAMILIAL
SEE METABOLIC DISORDERS INBORN.
HYPOLIPOPROTEINEMIAS FAMILIAL. TANGIER DISEASE
HIGH DENSITY LIPOPROTEINS
SEE LIPOPROTEINS BLOOD, HDL
HIGH ENERGY COMPOUNDS
SEE BIOENERGETICS, HIGH ENERGY COMPOUNDS
HIGH ENERGY PARTICLE ACCELERATORS
SEE RADIATION, PARTICLE ACCELERATORS
HIGH FIBER DIET
SEE NUTRITION, DIETARY CONSTITUENTS, DIETARY RESIDUES-
FIBERS
HIGH PRESSURE LIQUID CHROMATOGRAPHY
SEE PHYSICAL SEPARATION, CHROMATOGRAPHY, HIGH
PRESSURE LIQUID*
HIGH RENIN HYPERTENSION
SEE CARDIOVASCULAR DISORDERS, HYPERTENSION
(SYSTEMIC), ANGIOTENSIN-RENIN-ALDOSTERONE-
ASSOCIATED
HIGH RESIDUE DIET
SEE NUTRITION, DIETARY CONSTITUENTS, DIETARY RESIDUES-
FIBERS
HIGH RISK, DISEASE PRONENESS
SEE DISEASE PRONENESS-RISK
HIGH-RISK PREGNANCIES (INTRAUTERINE
FAILURE TO THRIVE)
SEE PREGNANCY DISORDERS, EMBRYO-FETAL GROWTH-
DEVELOPMENT DISORDERS (SEE ALSO APPROPRIATE
SPECIFICS)
HIGH SCHOOL
SEE EDUCATION, SCHOOLS, SECONDARY
HIP PROSTHESIS
SEE SKELETAL DISORDERS, ORTHOPEDICS, HIP PROSTHESIS
HIP REPLACEMENT PROSTHESIS
SEE SKELETAL DISORDERS, ORTHOPEDICS. HIP PROSTHESIS
HIP SURGERY
SEE SKELETAL DISORDERS, ORTHOPEDICS, HIP SURGERY
HIPPOCAMPAL FORMATION
SEE BRAIN, CEREBRUM, HIPPOCAMPAL FORMATION
HIRSUTISM
SEE DISEASES, SIGNS-SYMPTOMS, HIRSUTISM
HIRUDEN
SEE BLOOD COAGULATION, HIRUDEN
HISTAMINASE
SEE OXIDOREDUCTASES. AMINE OXIDASE (PYRIDOXAL-
CONTAINING)
HISTAMINE
SEE IMIDAZOLES, HISTAMINE
HISTAMINE ANTAGONISTS
SEE HYPERSENSITIVITY, ANTIALLERGY DRUGS, HISTAMINE
ANTAGONISTS
HISTAMINE LIBERATION
SEE IMIDAZOLES. HISTAMINE LIBERATION
(contd)
•Excludes routine methodology OR covers only general projects which preclude
••Oriented significantly to at»ve subject.
indexing at the specific level.
M Grant has subprojeds descnbing specific research aspects.
See Appendix for investigator's name and grant number
HIS
288
HOS
HISTIDINE
SEE CYCLIC AMINO ACIDS, HISTIDINE
HISTIDINE DECARBOXYLASE
SEE DECARBOXYLASES. HISTIDINE DECARBOXYLASE
HISTOCHEMISTRY AND CYTOCHEMISTRY
(GENERAL)*
** POlHL-0637017 0018 Cardiopulmonary and renal
pathology research center • Cytochemistry and immunology
of lymphoproliferative disorders (human)
** POlHL-08682-15 0011 Regulation of the cardiovascular
system - Histochemistry and ultrastructure of heart
innervation (dogs, ground squirrels)
** P01HL0897414 9002 Natural and experimental
atherosclerosis - Core-Histology and histochemistry
laboratory
" POlHL-12373-10 0016 Cardiopulmonary physiology and
pathophysiology - Histology-histochemlstry-Gough laboratory
P50HL-14230-07 0099 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Morphological, cytochemica! study of
normal and altered vasculature (mice)
POlHL-14388-07 0194 Regulation of the circulation in
pathological states - Dopamine-beta-hydroxylase localization
and release in hypertension
P01HL14388-07 0212 Regulation of the circulation in
pathological states - Role of dopamine in autonomic
activity
" P60HL17269-04 0021 National heart and blood vessel
research and demonstration center ■ Grovrth and
development of heart-Ultrastructure (dog, guinea pig, rat,
cat)
P50HL17651-04 0036 Ischemic heart disease specialized
center of research - Core facilities -Cardiovascular
pathology (human, dog)
ROlHL-18012-04 Cellular defects in nocturnal
hemoglobinuria (human)
R01HL19009-03 Morphometric analysis of the sinoatrial
node (ferret)
P50HL-19160-02 0002 Mucus abnormality in cystic
fibrosis ■ Ultrastructure, cytochemistry of pulmonary
secretion (human, rat)
P50HL-19171-02 0008 Pulmonary SCOR-Lung injury by
childhood infections - Host-parasite interaction-Electron
microscopy, radioautography, histochemistry
ROlHL-21008-02 Effect of pollutants on organotypic lung
cultures (rats)
" ROlHL-21038-01 Electrically induced cardiac EM-
histochemical changes (animals)
** ROlHL-21756-11 Vascular disease -Cytochemistry and
ultrastructure (human, rats, mice, hamsters)
ROlHL-22258-01 New aspects of pharmacology related to
carbonic anhydrase
** ROlHL-22402-01 Heparinbiophysical, chemical and
biological aspects (mice, human)
POlHL-22602-01 9001 Pathophysiology of the
endothelium - Morphology core
ROlHL-23161-01 0004 Biology of myocardial ischemia -
Structure of myofibrils and membranes In early Ischemia
(dogs, rabbit, rodents)
HISTOCOMPATIBILITY
SEE TISSUE COMPATIBILITY-TRANSPLANT, ISOALLOIMMUNITY
HISTOCOMPATIBILITY ANTIGENS
SEE TISSUE COMPATIBILITY-TRANSPLANT, ISOALLOANTIGENS
HISTOCOMPATIBILITY TYPING
SEE TISSUE COMPATIBILITY-TRANSPLANT,
HISTOCOMPATIBILITY TYPING
HISTOGENESIS
SEE GROWTH AND DEVELOPMENT. HISTOGENESIS
HISTOLOGY (GENERAL)*
SEE ALSO TISSUE (GENERAL)
SEE ALSO TISSUE AND CELL PREPARATION
** ROlHL-01770-26 Structural aspects of lung surfactant
system (rats)
** POlHL-08974-14 9002 Natural and experimental
atherosclerosis ■ Core-Histology and histochemistry
laboratory
ROlHL-12879-09 0010 Pulmonary transport and
metabolism in vivo ■ Lung morphometry in control and
edematous lungs (dogs)
ROlHL-14854-07 Lung and tissue mechanics (monkeys,
dogs)
ROlHL-16420-02
heart
** ROlHL-16935-05 Tissue organization and turnover in the
semilunar valve (dogs, rats)
ROlHL-18560-03 Cardiovascular adaptation to stress
(miniature sviinc)
ROlHL-19009-03 Morphometric analysis of the sinoatrial
node (ferret)
ROlHL-19379-03 Characterization of small-granule cells In
the lung (mammals)
ROlHL-20548-02 Innervation of the lung (rats, monkeys)
ROlHL-20902-02 Studies on marginal band system of
erythrocytes (amphibians, reptiles, fish)
POlHL-20994-02 9003 Dynamics of neutrophil elastase in
the lung - Autoradiography -Histology core
ROlHL-23206-01 Repetitive exercise and cardiac
enlargement (dogs)
Effect of training-detraining on the rat
HISTONES
SEE NUCLEOPROTEINS, HISTONES
HISTOPATHOLOGY (GENERAL)*
** ROlHL-04300-20 Fine structure of diseased glomeruli
(human, rats, dogs)
** POlHL-06370-17 0017 Cardiopulmonary and renal
pathology research center - Detection of pulmonary lesions-
Radiologic pathologic correlation
POlHL-08805-15 0049 Regulation of ventilation and
pulmonary circulation - Pulmonary hypertension produced
by Dirofilaria immitis in the dog
POlHL-08974-14 0005 Natural and experimental
atherosclerosis - Atherosclerosis, coronary heart disease
and sudden death (human)
** POlHL-10436-13 0009 A multidisciplinary study of
congenital heart disease - Pathophysiology and
morphogenesis of congenital heart disease (human)
ROlHL-10980-11 Ultrastructural renal pathology (human,
rats)
Physiologic pharmacology and its
POlHL-12738-10 0136
clinical applications -
P50HL-141 36-07 0004
obstructive diseases -
emphysema (human)
P50HL-14136-07 9003
obstructive diseases
P50HL-14212-07 0011
Pulmonary SCOR -Airv»ays
Morphometric studies of developing
Pulmonary SCOR -Airways
Pathology core (human, dogs)
Correlated studies of pulmonary
fibrosis - Pathology core (human, animal)
** P50HL-14214-07 0037 Newborn lung center for hyaline
membrane disease Core-Histopathology laboratories
ROlHL-14571-05 Myocardial preservation and coronary
reperfusion (baboons, dogs)
P50HL-15389-07 0018 Pulmonary SCOR -Hypersensitivity
pneumonitis - Pathology core (human, animal)
ROlHL-16757-04 'Autoimmune' thrombocytopenia (monkey)
POlHL-16769-05 0004 Pathobiologic and host defense
reactions in the lung - Pathogenesis of Pseudomonas and
Serratia pneumonias (rabbits)
POlHL-16769-05 0009 Pathobiologic and host defense
reactions in the lung - Electron microscopy and tissue
culture core laboratory
ROlHL-16952-05 Cardiovascular pathology (rats, rabbits)
P50HL-17646-04 0003 Study of ischemic heart disease -
Core pathology facility (human, dogs)
P50HL-17648-04 0031 Study of ischemic heart disease -
Ultrastructural consequences of myocardial ischemia (rat)
** P50HL-17651-04 0036 Ischemic heart disease specialized
center of research - Core facilities-Cardiovascular
pathology (human, dog)
P50HL-17655-04 0010 Study of ischemic heart disease -
Core facility-Cardiovascular pathology (human, animal)
P50HL-17682-04 0012 Study of ischemic heart disease -
Pathology core laboratory (human)
ROlHL-18473-04 Genesis of atherosclerotic lesions
(human, mules)
ROlHL-18631-03 Ultrastmctural correlates of myocardial
ischemia (rats, swine)
ROlHL-18714-04 Cardiovascular matrix-Morphogenesis
and maturation (human, chick embryo, mammal)
** ROlHL-18793-03 Clinical-pathologic studies of sudden
cardiac death (human)
** ROlHL-18824-03 Mechanisms of heart failure in
myopathic hamster
ROlHL-19000-03 Irreversible myocardial injury (rats)
ROlHL-19225-02 0001 Types and mechanims of
pulmonary hypertension - Structural changes (human,
animals)
ROlHL-193 78-03 Relation of mitochondrial changes to
cardiac failure (dogs, rats)
ROlHL-19381-03 Pathogenesis of viral induced
atherosclerosis (human, chicken)
** ROlHL-20400-03 Diabetic neuropathy and peripheral
vascular diseases (human, hamsters)
ROlHL-20500-02 Diabetic human brain microvascular
basement membrane (human)
** POlHL-20552-02 9001 The development and regression of
cardiac hypertrophy - Core A-Pathology
** ROlHL-20878-02 Cellular aspects of lung injury (rats,
rabbits)
** ROlHL-20895-03 0009 Cineangiographic studies of
cardiovascular system - Aortic changes in atheromatosis
(rabbits)
ROlHL-22341-01 Pathogenesis of atherosclerosis in rats
ROlHL-22583-02 Ultrastructural study of endothelium in
thrombosis (human)
ROlHL-22676-01 Pathogenesis in experimental interstitial
pneumonitis (rabbits)
ROlHL-22784-01 Ductus arteriosus closure -An arterial
lesion model (rabbits)
** ROlHL-22963-01 Symbolic logic analysis of congenital
heart disease (human)
HL-A ANTIGENS
SEE TISSUE COMPATIBILITY-TRANSPUNT. ISOALLOANTIGENS.
LEUKOCYTE
HL-A TYPING
SEE TISSUE COMPATIBILITY-TRANSPLANT,
HISTOCOMPATIBILITY TYPING, LEUKOCYTE TYPING
HMG-COENZYME A REDUCTASE
SEE OXIOOREDUCTASES, HMG-COENZYME A REDUCTASE
HMO
SEE HEALTH CARE PROFESSIONAL PRACTICE, GROUP
PRACTICE, HMO
HODGKIN'S DISEASE
SEE NEOPLASMS OF BLOOD AND RE SYSTEM, HODGKIN'S
DISEASE
HOLOGRAPHY
SEE OPTICS, PHOTOGRAPHY, HOLOGRAPHY*
HOLOGRAPHY, ACOUSTIC
SEE OPTICS, PHOTOGRAPHY, HOLOGRAPHY, ACOUSTIC*
HOLOGRAPHY, ULTRASONIC
SEE OPTICS, PHOTOGRAPHY, HOLOGRAPHY. ACOUSTIC*
HOME CARE
SEE HEALTH CARE SERVICES, HOME CARE
HOMEOSTASIS, HOMEOSTATIC CONTROL
SEE INFORMATION PROCESSING AND CONTROL (BIOLOGICAL),
HOMEOSTASIS
HOMOCYSTINE
SEE SULFUR AMINO ACIDS, HOMOCYSTINE
HOMOCYSTINURIA
SEE METABOLIC DISORDERS INBORN, AMINOACIDOPATHIES.
HOMOCYSTINURIA
HOMOPEPTIDES
SEE PEPTIDES, HOMOPEPTIDES
HOMOSERINE
SEE AMINO ACIDS, HOMOSERINE
HOMOTRANSPLANTATION
SEE TISSUE COMPATIBILITY-TRANSPUNT, TRANSPLANTATION
HOMOLOGOUS
HOMOZYGOTES
SEE GENETICS, GENOTYPES, HOMOZYGOTES
HORMONAL REGULATION AND CONTROL
(MECHANISMS)
SEE ENDOCRINOLOGY, HORMONAL REGUUTION AND
CONTROL (MECHANISMS)
HORMONE BINDING PROTEINS
SEE ENDOCRINOLOGY, HORMONE BINDING PROTEINS
SEE GLOBULINS. CORTICOSTEROID BINDING GLOBULIN
SEE HALOPROTEINS, THYROXINE BINDING PROTEINS
HORMONE RECEPTORS
SEE ENDOCRINOLOGY, HORMONE RECEPTORS
HORMONES
SEE ENDOCRINOLOGY. HORMONES
HORMONES ANALOGS
SEE ENDOCRINOLOGY. HORMONES ANALOGS
HORMONES BIOSYNTHESIS
SEE ENDOCRINOLOGY, HORMONES BIOSYNTHESIS
HORMONES INHIBITORS
SEE ENDOCRINOLOGY. HORMONES INHIBITORS
HORMONES METABOLISM
SEE ENDOCRINOLOGY. HORMONES METABOLISM
HOSPITAL FEES
SEE HEALTH ECONOMICS, HEALTH CARE COSTS-FINANCING
HOSPITAL INFORMATION SYSTEMS
SEE BIOMEDICAL SYSTEMS AUTOMATED, HEALTH CARE
FACILITIES (SYSTEMS) INFORMATION SYSTEMS
HOSPITAL SHARED SERVICES
SEE HEALTH CARE SERVICES. SHARED SERVICES
HOSPITALIZATION
SEE HEALTH CARE SERVICES, PATIENT CARE. HOSPITAL
PATIENTS
HOSPITALS, INTENSIVE CARE UNITS
** P50HL-14214-07 0034 Newborn lung center for hyaline
membrane disease - Core-Newborn intensive care unit
ROlHL-17993-04 0010 Ventricular dynamics from
surgically inserted markers - Postoperative cardiovascular
visualization (human)
Pulmonary SCOR-Pathophysiology.
Core -Clinical research center
Pulmonary SCOR-Pathophysiology.
Core -Demonstration and
** P50HL-19190-02 0001
management of IRDS
(infants)
P50HL-19190-02 0002
management of IRDS
dissemination
ROlHL-22636-01 Newborn lung function during
mechanical ventilation (human)
HOSPITALS, INTENSIVE CARE UNITS,
CORONARY
P60HL- 17269-04 0031 National heart and blood vessel
research and demonstration center - Computer-assisted
data acquisition and clinical data processing
** P50HL-17646-04 0001 Study of ischemic heart disease
Core clinical investigation unit
(contd)
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
**Onented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix tor investigator's name and grant number.
HOS
PbOHL 17682 04 0008
Clinical cote unit
Study ol ischemic heart disease
HOSPITALS, INTENSIVE CARE UNITS,
RESPIRATORY
PbOHL 19lbb02 0001 Pethophysiologv of pulmonary
edema Pulmonary edema study unit (human, dog)
ROIHL 22022 01 Respiiatory muscle dystunction in
tespiiatoiy lailute (human)
HOSPITALS, NURSERY
*• P50HL 1421407 0034 Newborn lung centei foi hyaline
membiane disease Core Newborn intensive cate unit
•• P50HL1919002 0001 Pulmonary SCOR Pathophysiology,
management ot IROS Core- Clinical research center
(infants)
HOSPITALS, OUTPATIENT FACILITIES
SEE ALSO HEALTH CARE SERVICES. PATIENT CARE. HOSPITAL
PATIENTS
•• P50HL 1413607 900S Pulmonary SCOR-Airways
obstructive diseases Clinical core
P60HL 1515807 0011 Comprehensive sickle cell center
Clinical services -Adult patients
P60HL1 5 158-07 0012 Comprehensive sickle cell center
Clinical services-Pediatric patients
•* P60HL-1 51 70-05 0001 Support tor center tor sickle cell
anemia Adult clinical services
P60HL 15170-05 0023 Support for center tor sickle cell
anemia - Comprehensive sickle cell clinic
** P60HL 16008-06 0001 Wayne State University
comprehensive sickle cell center - Patient care system
(children, adults)
ROlHL-17604-03 Wearable blood pressure and ECG
recording system
P60HL-20985-01 0009 Northern California sickle cell
center - Patient services (children, adults)
•* P50HL-21006 02 0001 Specialized center of research in
arteriosclerosis - Clinic and core program
** POlHL-21016-02 0017 Sickle cell anemia and other
hemoglobinopathies - The hereditary clinic core
"• NOlHV-12157-14 Lipid research clinic (human)
NOlHV-12158-10 Establishment of a lipid research clinic
** N01HV12 159-09 Lipid research clinic
** NOlHV-12160-15 Establishment of a lipid research clinic
** NOlHV-22913-09 Lipid research clinic
N01HV-229U-08 Establishment ol a lipid research clinic
** NOlHV-22915-11 Establishment of lipid research clinic
** NOlHV-22916-16 Establishment of a lipid research clinic
'* NOlHV-22932-09 Establishment of a lipid research clinic
•* NOlHV-32931-09 Establishment of a lipid research clinic
center
HOSPITALS ANALYSIS
" P60HL-17292-04 0030 Vermont Lung Center ■ Hospital
treatment of pneumonia
HOSPITALS INFECTIONS
SEE ALSO BACTERIAL DISEASES. STAPHYLOCOCCAL
INFECTIONS
SEE ALSO INJURIES, SURGICAL WOUND INFECTION
POlHL-06370-17 0016 Cardiopulmonary and renal
pathology research center - Endocarditis with pulmonary
artery catheters (dogs)
HOSPITALS PATIENTS (CARE)
SEE HEALTH CARE SERVICES. PATIENT CARE. HOSPITAL
PATIENTS
HOSPITALS UTILIZATION
SEE ALSO HEALTH CARE (SERVICESXRESOURCES)
UTILIZATION
NOlHR-72974-01 Self-management systems for asthmatic
children
HOST-MICROORGANISM
SEE ENVIRONMENT. ECOLOGY ORGANISIiflS, HOST-ORGANISM
HOST-ORGANISM
SEE ENVIRONMENT. ECOLOGY ORGANISMS. HOST-ORGANISM
HOST-RESTRICTION ENDONUCLEASES
SEE NUCLEASES. ENDONUCLEASES (GENERAL)
HOST-VIRUS
SEE VIRUS DISEASE CHARACTERISTICS. HOST-VIRUS
HOSTILITY
SEE PSYCHOLOGY. BEHAVIOR, AGGRESSION
HOUSING
SEE SOCIOENVIRONMENT. RESIDENCE CHARACTERISTICS.
HOUSING
HOWLERS
SEE MAMMALS, PRIMATES. MONKEYS AND APES
(ANTHROPOIDS. NON-HUMAN), NEW WORLD MONKEYS
(PUTYRHINES)*
HPP(ALLOPURINOL)
SEE DIAZOLODIAZINES. PYRAZOLOPYRIMIDINES, ALLOPURINOL
HUMAN AND HUMAN RELATED POPULATION
STUDIES
SEE POPULATION STUDIES HUMAN
289
HUMAN EMBRYOLOGY AND DEVELOPMENT
STUDY SECTION
Sff EMBKVOIOCY (HUMAN) AND OEVELOPMENI STUDY
SfCIION
HUMIDITY
SEE ENVIRONMENl, ATMOSPHfRf. HUMIDITY
HUMORAL ANTIBODIES (GENERAL)
SEE IMMUNOIOGY. ANTIBODIES
HUMORAL ANTIBODIES SENSITIZING
SEE HYPERSENSITIVITY, SENSITIZING ANTIBODIES HUMORAL
HUMORAL (ANTIBODY) HYPERSENSITIVITY
SEE HYPERSENSITIVITY. IMMEDIATE HYPERSENSITIVITY
HUMORAL IMMUNITY
SEE IMMUNITY, HUMORAL IMMUNITY
HYALINE MEMBRANE DISEASE
SEE CONGENITAL ABNORMALITIES, RESPIRATORY DISTRESS
SYNDROME
HYALINOSIS, CUTANEOUS-MUCOSAL
SEE LIPOGRANULOMATOSES. LIPOID PROTEINOSIS
HYALURONATE LYASE
SEE POLYSACCHARIDE CO LYASES. HYLURONATE LYASE
HYALURONIC ACID
SEE POLYSACCHARIDES. GLYCOSAMINOGLYCANS,
HYALURONIC ACID
HYALURONIDASE
SEE CARBOHYDRASES. HYALURONIDASE
HYALURONOGLUCOSIDASE
SEE CARBOHYDRASES, HYALURONIDASE
HYBRID CELLS
SEE CELL HYBRIDS
HYBRID ENZYMES
SEE ENZYMES, HYBRID ENZYMES
HYBRID NUCLEIC ACIDS
SEE NUCLEIC ACIDS. UNNATURAL NUCLEIC ACIDS, HYBRID
NUCLEIC ACIDS
HYBRIDS
SEE GENETICS, GENOTYPES. HETEROZYGOTES
HYDATIDIFORM MOLE
SEE PREGNANCY. PLACENTAL NEOPLASMS. HYDATIDIFORM
MOLE
HYDRATION REACTIONS
SEE CHEMICAL REACTIONS. HYDRATION
HYDRAZINOPHTHALAZINE
SEE AZO COMPOUNDS, HYDRAZINOPHTHAUZINE
HYDROCARBONS
SEE ALSO ALKANES
SEE ALSO ALKYNES
SEE ALSO CYCLICS, CARBOPOLYCYCLICS
POlHL-031 74-23 0010 Mechanisms of acute vascular
reaction to Injury ■ Search for mutagens in the human
blood (bacteria, animals)
POlHL-031 74-23 0011 Mechanisms of acute vascular
reaction to injury - Mutagen metabolism by artery wall in
etiology of atherosclerosis (human, animals)
POlHL-063 14-17 0051 Immunologic mechanisms in
cardiovascular disease ■ Conformational studies of
phospholipid membranes and proteins
RGlHL-20996-02 Structural and reactivity of iron and
cobalt complexes
HYDROCHOLERETICS
SEE BILE, CHOLAGOGUES AND CHOLERETICS
HYDROCORTISONE
SEE ADRENAL CORTEX HORMONES, HYDROCORTISONE
HYDRODYNAMICS
SEE PHYSICAL PROPERTIES. FLUID DYNAMICS (GENERAL)
HYDROGEN
POlHL-16878-05 0004 Control of ventilation in health
and disease - Neurotransmitters in the respiratory system
(cats)
R23HL-2 1434-02 Intrinsic control of coronary blood flow by
chemicals (guinea pigs)
HYDROGEN, TRITIUM*
ROlHL-13901-08 Ontogeny, ultrastructure. function in
lymphatic system (birds, fish, mammals)
ROlHL-17898-03 Cell membranes and plasma lipoproteins
(human, swine)
ROlHL-19223-03 Control of cholesterogenesis in leukocytes
and liver (rats, human)
ROlHL-21831-05 Determining sequences from hemoglobin
messenger RNA (mice, chickens, rabbits)
ROlHL-22039-02 Ion transport in cardiac muscle (dogs.
rodents, cattle)
ROlHL-22567-01 Validation of a cholesterol absorption
method in man
HYD
HYDROGEN BOND
SI I CHIMK.AI DONO'. HYOROGIN BONO
HYDROGEN GENERATING TISSUE BLOOD FLOW
PROBE
SFf CARDIOVASCUIAR DISORDERS DIAGNOSIS. BLOOD FLOW
MEASUREMENTS. HYDROGEN*
HYDROGEN-ION CONCENTRATION
SEf ACIDS RASES. HYDROGEN ION CONCENIRAIION
HYDROGEN PEROXIDE
SEE PEROXIDES. HYDROGEN PEROXIDE
HYDROGEN PUMP
SEE BIOLOGICAL TRANSPORT. ACTIVE TRANSPORT. ION
PUMPS. HYDROGEN PUMP
HYDROGEN TRANSPORT
SEE CHEMICAL TRANSFER. HYDROGEN TRANSPORT
HYDROGENOMONAS
SEE BACTERIA. PSEUDOMONADALES. PSEUDOMONAS*
HYDROLASES
SEE ALSO AMINOHYDROLASES
SEE ALSO CARBOHYDRASES
SEE ALSO ESTERASES
SEE ALSO N-GLYCOSYLHYOROLASES
SEE ALSO PHOSPHATASES
SEE ALSO PROTEASES AND PEPTIDASES, PEPTIDASES
ROIHL 03299 21 Dietary effects on cholesterol metabolism
(rats, rabbits)
ROIHL 11897-11 Pathogenesis of experimental
atherosclerosis (rabbits, guinea pigs)
POIHL 12373-10 0006 Cardiopulmonary physiology and
pathophysiology - Fatty acid metabolism -Regulation,
implications (human, mammals, birds)
** P50HL-14153-07 0004 Johns Hopkins Lung Center-
Chronic diseases of airways - Macrophage enzymes in lung
injury, inflammation and repair (rabbit)
R01HL16637-04 Development and regression of cardiac
hypertrophy (rats)
ROlHL-18089-04 Fatty acid metabolism in heart and its
regulation (swine, rats)
ROIHL 18157-04 Subcellular events in atherosclerosis
(human, rabbits, calves)
ROlHL-18631-03 Ultrastructural correlates of myocardial
ischemia (rats, swine)
ROIHL 18682-03 Protein kinase and cholesterol
metabolism in aorta (rabbits)
** R01HL-19072 03 Modification of tissue Injury in
myocardial infarction (dogs, human)
ROlHL-19083-02 Rapid specific micro measurement of
blood cholesterol
** POlHL-19717-02 0002 Response of the lung to injury -
Prolyl hydroxylase, lysyl hydroxylase and lung collagen
biosynthesis (rabbits)
POlHL-19717-02 0010 Response of the lung to injury -
Proteoglycans in lung function and structure (hamsters)
ROlHL-19936-02 Unsaturated fatty acid biosynthesis in
the aorta (rats)
R01HL-21095-02 Enzymes of M tuberculosis and
obstructive lung disease (human, rodents)
*♦ R23HL-21411-02 Control of extracellular lysosomal
hydrolase levels (rats)
ROlHL-21498-02 Pathophysiology of edema (rats, cats)
ROlHL-21756-11 Vascular disease-Cytochemistry and
ultrastructure (human, rats, mice, hamsters)
R01HL-23206-01 Repetitive exercise and cardiac
enlargement (dogs)
HYDROLYSIS
SEE CHEMICAL REACTIONS, SOLVOLYSIS, HYDROLYSIS
HYDRONEPHROSIS
SEE KIDNEY DISORDERS, HYDRONEPHROSIS
HYDROPHOBIC BONDS
SEE CHEMICAL BONDS, HYDROPHOBIC
HYDROPS
SEE BODY FLUID BALANCE, EDEMA
HYDROPYRIDINES
SEE PYRIDINES, HYDROPYRIDINES
HYDROSTATIC PRESSURE
SEE PHYSICAL PROPERTIES, FLUID STATE, HYDROSTATIC
PRESSURE
HYDROTHERAPY
SEE THERAPY. HYDROTHERAPY
HYDROXAMIC ACIDS
SEE AMINES, HYDROXYLAMINES, HYDROXAMIC ACIDS
2-HYDROXYBENZOIC ACID
SEE PHENYLCARBOXYLAIES, SALICYLATES
BETA-HYDROXYBUTYRATE DEHYDROGENASE
SEE OXIDOREDUCTASES, BETA-HYDROXYBUTYRATE
DEHYDROGENASE
BETA-HYDROXYBUTYRIC ACID
SEE FAHY ACIDS, BETA-HYDROXYBUTYRIC ACID
(contd)
•Excludes routine methodology OR covers only general projects which preclude
"•Oriented significantly to above subject
indexing at the specific level
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
mm^>,
HYD
HYDROXYCHOLESTEROLS
SEE CHOLESTANE SERIES, HYDROXYCHOLESTEROLS
HYDROXYDAUNOMYCIN
SEE ANTIBIOTICS, ADRIAMYCIN
10-HYDROXYDECANOIC ACID
SEE FATTY ACIDS. 10-HYDROXYDECANOIC ACID
6-HYDROXYDOPAMINE
SEE PHENYLALKYLAMINES, CATECHOLAMINES, L-
HYDROXYDOPAMINE
HYDROXY FATTY ACIDS
SEE FATTY ACIDS, HYDROXY FATTY ACIDS
HYDROXYLASES (GENERAL)
SEE OXYGENASES, HYDROXYUSES (GENERAL)
HYDROXYLATION REACTIONS
SEE CHEMICAL REACTIONS, HYDROXYLATION
HYDROXYLYSINE
SEE OIAMINO ACIDS, LYSINE, HYDROXYLYSINE
HYDROXYMETHYIGLUTARYL COENZYME A
REDUCTASE
SEE OXIDOREDUCTASES, HMG-COENZYME A REDUCTASE
HYDROXYPROUNE
SEE CYCLIC AMINO ACIDS, PROLINE. HYDROXYPROUNE
HYDROXYPROPIONIC ACID
SEE FATTY ACIDS, LACTATES
4-HYDROXY-1 H PYRAZOLO(3,4-D)PYRIMiDINE
SEE OIAZOLODIAZINES, PYRAZOLOPYRIMIDINES, ALLOPURINOL
HYDROXYPYRIDINES
SEE PYRIDINOLS
HYDROXYSTEROIDS
SEE STEROIDS, HYDROXYSTEROIDS
5-HYDROXYTRYPTAAAINE
SEE BENZOPYRROLES, SEROTONIN
HYPERALDOSTERONISM
SEE ADRENAL GLANDS DISORDERS. HYPERALDOSTERONISM
HYPERALIMENTATION (THERAPY)
SEE NUTRITION. DIET THERAPEUTIC. HYPERALIMENTATION
(THERAPY)
HYPERBARIC FACILITY
SEE ENVIRONMENTAL CHAMBER CONTROLLED, HYPERBARIC
FACILITY
HYPERBARIC OXYGENATION
SEE RESPIRATORY ASSIST AND OXYGEN ADMINISTRATION,
HYPERBARIC OXYGENATION
HYPERBILIRUBINEMIA NEONATAL TRANSIENT
SEE JAUNDICE NEONATAL (TRANSIENT)
HYPERBILIRUBINEMIA, NEONATAL (TRANSIENT)
(IDIOPATHIC) (PHYSIOLOGICAL)
SEE JAUNDICE NEONATAL (TRANSIENT)
HYPERCALCEMIA
SEE CALCIUM (MINERAL) IMBAUNCES, HYPERCALCEMIA
HYPERCAPNIA
SEE RESPIRATORY GAS LEVELS, HYPERCAPNIA
HYPERCHOLESTEREMIA
SEE LIPIDS BLOOD, HYPERCHOLESTEREMIA
HYPERCHOLESTEREMIA ESSENTIAL FAMILIAL
SEE METABOLIC DISORDERS INBORN,
HYPERLIPOPROTEINEMIAS FAMILIAL, TYPE II
HYPERCHYLOMICRONEMIA WITH
HYPERBETALIPOPROTEINEMIA FAMILIAL
SEE METABOLIC DISORDERS INBORN.
HYPERLIPOPROTEINEMIAS FAMILIAL, TYPE V
HYPERGLYCEMIA
SEE CARBOHYDRATE BALANCE, HYPERGLYCEMIA
HYPERGLYCEMIC-GLYCOGENOLYTIC FACTOR OF
PANCREAS
SEE PANCREAS HORMONES, GLUCAGON
HYPERGLYCEMIC OBESITY HEREDITARY
SEE METABOLIC DISORDERS INBORN, OBESITY HEREDITARY
HYPERGLYCEMIC
HYPERHYDRATION
SEE BODY FLUID BALANCE, BODY WATER EXCESS
HYPERI/MMUNIZATION
SEE IMMUNITY, IMMUNIZATION, HYPERIMMUNIZATION
HYPERINSULINISM
SEE PANCREATIC ISLETS DISORDERS, HYPERINSULINISM
HYPERKALEMIA
SEE BODY FLUID BAUNCE, IONIC, HYPERKALEMIA
290
HYPERKINESIA (NEUROMOTOR DISORDERS)
SEE NEUROMOTOR DISORDERS. HYPERKINESIA
HYPERUPEMIA
SEE LIPIDS BLOOD. HYPERLIPEMIA
HYPERUPEMIA ESSENTIAL FAMILIAL
SEE METABOLIC DISORDERS INBORN.
HYPERLIPOPROTEINEMIAS FAMILIAL. TYPE I
HYPERLIPEMIA HYPERGLYCEMIC
SEE METABOLIC DISORDERS INBORN. OBESITY HEREDITARY
HYPERGLYCEMIC
HYPERLIPEMIA IDIOPATHIC
SEE METABOLIC DISORDERS INBORN.
HYPERLIPOPROTEINEMIAS FAMILIAL. TYPE I
HYPERLIPIDEMIA
SEE LIPIDS BLOOD. HYPERLIPEMIA
HYPERLIPOPROTEINEMIA
SEE LIPOPROTEINS BLOOD. HYPERLIPOPROTEINEMIA
HYPERLIPOPROTEINEMIA FAMILIAL, TYPE I
SEE METABOLIC DISORDERS INBORN.
HYPERLIPOPROTEINEMIAS FAMILIAL, TYPE I
HYPERLIPOPROTEINEMIA FAMILIAL, TYPE II
SEE METABOLIC DISORDERS INBORN,
HYPERLIPOPROTEINEMIAS FAMILIAL, TYPE II
HYPERLIPOPROTEINEMIA FAMILIAL, TYPE III
SEE METABOLIC DISORDERS INBORN,
HYPERLIPOPROTEINEMIAS FAMILIAL. TYPE III
HYPERUPOPROTEINEMIA FAMILIAL, TYPE IV
SEE METABOLIC DISORDERS INBORN.
HYPERLIPOPROTEINEMIAS FAMILIAL. TYPE IV
HYPERUPOPROTEINEMIA FAMILIAL, TYPE V
SEE METABOLIC DISORDERS INBORN,
HYPERLIPOPROTEINEMIAS FAMILIAL, TYPE V
HYPERUPOPROTEINEMIAS FAMILIAL
SEE METABOLIC DISORDERS INBORN,
HYPERLIPOPROTEINEMIAS FAMILIAL
HYPEROSMOLARITY, BLOOD
SEE BLOOD OSMOTIC PRESSURE, HYPEROSMOURITY
HYPEROSMOLARITY, BODY FLUIDS
SEE BODY FLUID BALANCE, OSMOTIC PRESSURE,
HYPEROSMOURITY
HYPEROXIA
SEE RESPIRATORY ASSIST AND OXYGEN ADMINISTRATION,
HYPEROXIA
HYPERPARATHYROIDISM
SEE PARATHYROID GLANDS DISORDERS,
HYPERPARATHYROIDISM
HYPERPLASIA (GENERAL)
SEE GROWTH ABNORMAL, HYPERPLASIA (GENERAL)
HYPERPNEA
SEE RESPIRATORY FUNCTION, HYPERPNEA
HYPERPREBETA AND
HYPERBETALIPOPROTEINEMIA FAMILIAL
SEE METABOLIC DISORDERS INBORN,
HYPERLIPOPROTEINEMIAS FAMILIAL, TYPE III
HYPERPREBETAUPOPROTEINEMIA FAMILIAL
SEE METABOLIC DISORDERS INBORN,
HYPERLIPOPROTEINEMIAS FAMILIAL, TYPE IV
HYPERSENSITIVITY (GENERAL)
SEE ALSO ALLERGY AND IMMUNOLOGY STUDY SECTION
SEE ALSO IMMUNOLOGY (GENERAL)
SEE ALSO TISSUE COMPATIBILITY-TRANSPLANT, IMPUNT
COMPATIBILITY
** ROlHL-01803-23 0011 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Immunopathologic consequences of
cigarette smoking (human, rabbits, plants)
ROlHL-01803-23 0015 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Immunologic endothelial injury and lipid
diet atherosclerosis (rabbits, monkey)
** R01HL01803-23 0021 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Induction of IgE antibodies to antigen
from tobacco and cigarette smoke (rabbits)
ROlHL-03919-20 The cell suface of streptococci (rats,
human)
** ROlHL-08399-15 Platelet injury in infections and allergic
diseases (human)
ROlHL-1058212 Thrombosis and hemostasis-Analysis,
methods and standards (human, cattle, venom)
R01HL15124-05 Genesis of hypertension in renal disease
(human, dogs)
ROlHL-16768-04 The sympathetic nervous system and the
arterial wall (rabbits, pigeons)
P50HL-1915602 0004 Pulmonary SCOR -Chronic diseases
of airways - Interactions between mast cells, mediators
and nerves in canine asthma
R23HL-2201101 Adrenergic receptor cyclase system in
sensitized lung (rats, guinea pigs)
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
•'Oriented significantly to above subject.
HYP
HYPERSENSITIVITY, ALLERGENS
SEE ALSO IMMUNOLOGY, ANTIGENS
SEE ALSO IMMUNOLOGY, HAPTENS
SEE ALSO TOXICOLOGY, ANIMAL POISONS, INSECTS BITES
STINGS VENOMS
R01HL01803-23 0022 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Cardiac and pulmonary anaphylaxis
induced by tobacco glycoprotein (rabbits)
P01HL17382-05 0002 Chemical mediators of acute
pulmonary disorders ■ Chemical mediators and respiratory
mechanics in guinea pigs
P50HL-18828-03 0006 Specialized center of research in
thrombosis - Etiology and pathogenesis of atherosclerosis
(rabbit, monkey, rat, human)
P50HL-19155-02 0004 Pathophysiology of pulmonary
edema - Physical and chemical effects of multiple
pulmonary emboli (sheep)
P50HL-19156 02 0004 Pulmonary SCOR -Chronic diseases
of airways - Interactions between mast cells, mediators
and nerves in canine asthma
P50HL-19156-02 0005 Pulmonary SCOR-Chronic diseases
of airways - Vagal receptors in the airway-Epithelial injury
and antigen (dog. cat. rabbit)
** R01HL-22582-0I Pulmonary and circulatory alterations
induced by IGE
HYPERSENSITIVITY, ALLERGENS AIRBORNE
SEE ALSO RESPIRATORY DISORDERS. RESPIRATORY SYSTEM
TOXINS
P50HL-14136-07 0016 Pulmonary SCOR-Airways
obstructive diseases - Environmental factors In airways
obstructive diseases (human)
P50HL-14153-07 0011 Johns Hopkins Lung Center-
Chronic diseases of airways - Allergy, airways reactivity
and asthma in human ragweed allergy
P50HL-14153-07 0012 Johns Hopkins Lung Center-
Chronic diseases of airways - Aspirin intolerance in
reversible lung disease (human)
P50HL-14153-07 0016 Johns Hopkins Lung Center-
Chronic diseases of airways - Airways defense mechanisms
(dogs)
P50HL15389 07 0001 Pulmonary SCOR -Hypersensitivity
pneumonitis - Clinical studies of hypersensitivity
pneumonitis
** P50HL-15389-07 0008 Pulmonary SCOR-Hypersensitivity
pneumonitis - Milwaukee patient study-Hypersensitivity
pneumonitis
P50HL-15389-07 0011 Pulmonary SCOR-Hypersensitivity
pneumonitis - Animal model-Hypersensitivity pneumonitis
in rabbits
P50HL-19170-02 0003 Harvard pulmonary SCOR-Chronic
diseases of the airways - Mechanisms of bronchial
reactivity to acute and chronic airway challenge (dog)
P50HL-19170-02 0007 Harvard pulmonary SCOR-Chronic
diseases of the airways - Therapy effect on airway
obstruction in acute asthma (human)
ROlHL-19733-03
lungs (rabbits)
ROlHL-19806-03
(human, rabbits)
ROlHL-19819-03 Mitogen induced interstitial pneumonitis
(rabbits)
** ROIHL-19873-03 Pulmonary responses to inhaled antigen
(rabbits, guinea pigs)
ROlHL-20783-02 Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
ROlHL-23631-01 Immunogenetic factors in allergic
respiratory diseases (human)
HYPERSENSITIVITY, ANAPHYLAXIS
** ROlHL-01803-23 0022 Arteriosclerosis, glomerulonephritis,
rheumatic fever Cardiac and pulmonary anaphylaxis
induced by tobacco glycoprotein (rabbits)
POlHL-08682-15 0019 Regulation of the cardiovascular
system - Hepatic immunophysiology and host-defense in
shock (rat. dog, human)
POlHL-08682-15 0020 Regulation of the cardiovascular
system - Hepatic metabolic basis of shock (rat)
M POlHL-10342-13 The integrated function of respiration
and circulation
** PGlHL-10342-13 0028 The integrated function of
respiration and circulation - Mediator release,
hemodynamics and respiratory function in anaphylaxis
(dogs)
** ROlHL-12421-10 Pathophysiology of circulatory shock
(dogs, baboons)
P50HL-14153-07 0013 Johns Hopkins Lung Center-
Chronic diseases of airways - Pulmonary mechanics and
mediators of allergic reactions (guinea pigs, human)
P50HL-14153-07 0014 Johns Hopkins Lung Center-
Chronic diseases of airways - Mediator release in asthma
(human)
P50HL-14187-07 0012 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses - Vasoactive
mediators in pulmonary disease (human, animal)
POlHL-14985-07 0007 Adaptation to hypoxia - Control of
pulmonary circulation, histamine and the sympathetics
(animals)
POlHL-14985-07 0010 Adaptation to hypoxia - Pulmonary
mast cell (animals)
ROlHL-16677-06 Autonomic nervous system function in
bronchial asthma (human, guinea pig. rabbit)
(contd)
Absorption of antigen through inflamed
Chemotactic control of airway phagocytes
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
HYP
'• POIHI 16411 04 0001 Blood systems in cosjulation and
vessel disease Moleculai studies ot the role ol
complement in blood coagulation (human. labbits)
•• POIHI 16411 04 0004 Blood systems in coagulation and
vessel disease Platelets reactions in vascular iniuni
(human, animals)
POIHI 16411 04 OOOS Blood systems in coagulation and
vessel disease Chemical analysis ol sefum components
associated with coagulation (human, animal)
M PO1H11738205 Chemical mediators of acute pulmonary
disorders
POIHL 1738205 0002 Chemical mediators ol acute
pulmonary disorders Chemical mediators and respiratory
mechanics in guinea pigs
POIHL W38205 0003 Chemical mediators of acute
pulmonary disorders ■ Chemical mediators relevant to
allergic reactions (human, guinea pigs)
ROl HI 1906203 Pharmacologic control ol mast cell
phosphodiesterase (human, rats)
POIHL 1971702 0037 Response ol the lung to injury •
Catecholamines, prostaglandins and nucleotides in
pulmonary lunction (animals)
•• R01HL19795-03 Synthesis ol anaphylatoxic and
leucotactic peptides (human)
** ROIHL-20220 03 Anaphylato»ins as inllammatory and
chemotactic agents (guinea pig. rabbit, human)
ROlHL-20787-02 Thromboxanes and prostaglandins-
Biochemical pharmacology (rabbits, human)
** R23HL-2 1089-02 Localization of mediators in dispersed
lung cells (guinea pigs, human)
R23HL-2U50-02 Regulation ol airway mucous glands and
ion transport (dogs, ascaris)
ROlHL-21565 02 Pathogenesis ol Inllammatory lung injury
(rats, rabbits)
R23HL-220U 01 Adrenergic receptor cyclase system in
sensitized lung (rats, guinea pigs)
ROlHL-22555-01 Structure and lunction ol platelet
activating lactor (rabbits, human)
HYPERSENSITIVITY, ANAPHYLAXIS,
SHWARTZMAN PHENOMENON
ROlHL-14739-06 The role ol leukocytes in thrombotic
disease (human, dogs)
** POlHL-1641104 0004 Blood systems in coagulation and
vessel disease Platelets reactions in vascular injury
(human, animals)
POlHL-18576-03 0007 Thrombosis research program
project - Relationships between coagulability and
thrombosis (human, animals)
HYPERSENSITIVITY, ANTIAUERGY DRUGS
SEE ALSO HYPERSENSITIVITY DESENSITIZATION
SEE ALSO RESPIRATORY DRUGS. BRONCHODILATORS
** ROlHL-23586-06 Pharmacologic control of hypersensitivity
phenomena (human)
HYPERSENSITIVITY, ANTIAUERGY DRUGS,
HISTAMINE ANTAGONISTS
ROlHL-03941-18 Uterine blood flow and changes in
pregnancy (sheep)
R01HL04512-19 Ultrastructural studies of capillary
permeability (rats, mice)
POlHL-06285-18 0186 Cardiovascular-respiratory
physiology and biochemistry - Leukocyte hormone receptors
and cyclic nucleotides (tissue culture)
POlHL-06664-17 0010 Cardiopulmonary lunction in
remediable vascular disease - Ischemia and acute renal
lailure (rats)
POlHL-14388-07 0187 Regulation of the circulation in
pathological states - Histamine and circulatory control
POlHL-14985-07 0007 Adaptation to hypoxia - Control of
pulmonary circulation, histamine and the sympathetics
(animals)
ROlHL-15002-07 Biochemical pharmacology of guanylate
cyclase in lung (cattle, rats)
ROlHL-1624005 The cardiac histamine receptor (rabbits.
guinea pigs)
ROlHL-16524-02 Selective inhibitors of prostaglandin
biosynthesis (dogs)
P01HL-16769-05 0002 Pathobiologic and host defense
reactions in the lung - Pathogenesis of complement
dependent injury to the lungs (rabbits)
P50HL-17648-04 0023 Study ot ischemic heart disease -
Chemical mediators ol inflammation in acute myocardial
infarction (mammals)
ROlHL-18002-03 Circulatory shock, trauma and RE-system
lunction (rats)
POlHL-18576-03 0003 Thrombosis research program
project - Biocompatible materials
ROlHL-18936-02 Heart preservation and transplantation
studies (rat)
** P50HL19153-02 0002 SCOR-Pulmonary edemas -Eitology.
pathogenesis - Lung fluid dynamics-Classical mediators
and their inhibitors (sheep)
P50HL-19156-02 0005 Pulmonary SCOR-Chronic diseases
ol airways • Vagal receptors in the airway-Epithelial injury
and antigen (dog. cat. rabbit)
ROlHL-207 19-02 Cold induced pulmonary hypertension
(cattle)
ROlHL-20783-02 Airway reactivity -B-adrenoceptors and
prostaglandins (guinea pigs)
ROlHL-20989-01 Pathophysiology of bronchial asthma
(sheep, dogs)
ROIHI 2213602
ROIHI 23593 01
secretion (rats)
291
Histamine and cardiac adenyl cyclase
Mast cell granules Structure and
HYPERSENSITIVITY, ATOPY
SEE ALSO HYPERSENSITIVITY. ALLERGENS AIRBORNE
SEE ALSO HYPERSENSITIVITY. RESPIRATORY
HYPERSENSITIVITY
SEE ALSO HYPERSENSITIVin. SKIN SENSITIZING ANTIBODY
P50HL 1413607 0009 Pulmonary SCOR Airways
obstructive diseases Tuscan epidemiological study of
airways obstructive disease (human)
*• P50HL 1415307 0011 Johns Hopkins Lung Center -
Chronic diseases of airways Allergy, airways reactivity
and asthma in human ragweed allergy
P50HL 1915602 0001 Pulmonary SCOR-Chronic diseases
of airways Irritability of airways induced by epithelial
damage in healthy subiects (human)
ROIHL 22555-01 Structure and lunction ol platelet
activating lactor (rabbits, human)
HYPERSENSITIVITY, DELAYED HYPERSENSITIVITY
SEE ALSO HYPERSENSITIVITY. LYMPHOKINES
SEE ALSO HYPERSENSITIVITY, LYMPHOKINES, LEUKOTAXIC
FACTOR
SEE ALSO HYPERSENSITIVITY, LYMPHOKINES, MIGRATION
INHIBITORY FACTOR
SEE ALSO HYPERSENSITIVin. SENSITIZING ANTIBODIES NON
HUMORAL
SEE ALSO HYPERSENSITIVITY. TRANSFER FACTOR
(HYPERSENSITIVITY)
SEE ALSO IMMUNITY. CELLULAR IMMUNITY (GENERAL)
SEE ALSO IMMUNOPATHOLOGY. AUTOIMMUNE DISORDERS
SEE ALSO TISSUE COMPATIBILITY-TRANSPLANT.
ISOALLOIMMUNITY
R01HL01623-24 Antigens related to gralt rejection
(rabbits, rats)
ROlHL-01803-23 0018 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Fetal immunization in pathogenesis ol
glomerulonephritis in adult (rabbit)
POlHL-06285-18 0186 Cardiovascular-respiratory
physiology and biochemistry - Leukocyte hormone receptors
and cyclic nucleotides (tissue culture)
ROlHL-08695-15 0004 Orthotopic heart transplantation -
Transplantation immunology-Avian antibody studies
(chickens, rats, rabbits)
POlHL-08805-15 0049 Regulation ol ventilation and
pulmonary circulation - Pulmonary hypertension produced
by Dirolilaria immitis in the dog
P50HL-142 12-07 0013 Correlated studies ol pulmonary
librosis - Mechanism of beryllium pathogenicity in the lung
(human, rabbit, guinea pig)
P50HL 15092-07 0002 Immune and fibrotic response to
occupational environments - Longitudinal study ol
sandblastcrs silicosis (human)
P50HL- 15092-07 0006 Immune and librotic response to
occupational environments - Immunologic studies in
silicosis (human, rabbits, hamsters, guinea pigs)
P50HL-1 5092-07 0008 Immune and librotic response to
occupational environments - Animal models of asbestosis
(hamsters)
P50HL- 15092-07 0011 Immune and fibrotic response to
occupational environments - Respiratory and immunologic
responses in coffee plant workers
POlHL-15195-04 0004 Program project in biological
materials - Biological evaluation and surface interaction
studies (dogs)
P50HL-15389-07 0001 Pulmonary SCOR-Hypersensitivity
pneumonitis - Clinical studies of hypersensitivity
pneumonitis
P50HL-15389-07 0008 Pulmonary SCOR-Hypersensitivity
pneumonitis - Milwaukee patient study-Hypersensitivity
pneumonitis
P50HL-15389-07 0011 Pulmonary SCOR-Hypersensitivity
pneumonitis - Animal model-Hypersensitivity pneumonitis
in rabbits
P50HL-15389-07 0012 Pulmonary SCCR-Hypersensitivity
pneumonitis - Animal model-lmmunologic lung disease in
guinea pigs
P50HL-15389-07 0013 Pulmonary SCOR -Hypersensitivity
pneumonitis - Animal model-Pulmonary mycotoxicosis
(rabbit, guinea pig)
P50HL-15389-07 0017 Pulmonary SCOR-Hypersensitivity
pneumonitis - Immunology core (human)
P60HL-15999-05 0008 Miami comprehensive sickle cell
center - Cyanate effect on host delense -Cellular and
humoral (human, guinea pig, rabbits)
ROlHL-16642-05 Biochemistry and pathophysiology of
plasma kallikrein (human, animals)
M POlHL-16769-05 Pathobiologic and host defense reactions
in the lung
** POlHL-16769-05 0003 Pathobiologic and host defense
reactions in the lung - Pathobiologic mechanisms of
delayed sensitivity reactions in the lung (animals)
** POlHL-16769-05 0010 Pathobiologic and host defense
reactions in the lung - Bronchus associated lymphoid
tissue and delayed hypersensitivity (rabbits)
ROlHL-19732-03 Lymphokines in pulmonary
granulomatous inflammation (mice)
ROlHL-19741-03 Murine CRD-A model of chronic
pulmonary inflammation (mice, rats)
ROlHL-19873-03 Pulmonary responses to inhaled antigen
(rabbits, guinea pigs)
HYP
ROIHI 20104 03 Pulmoniiy |finulomitout inll»mm«tion»
(mice)
ROIHI 22301 01 Immunogenelics ol chronic pulmonary
inllammation (mice)
•* ROIHI 2358606 Pharmacologic control ol hypeiseniilivity
phenomena (human)
HYPERSENSITIVITY, IMMEDIATE
HYPERSENSITIVITY
SEE ALSO HYPERSENSITIVITY. ANAPHYLAXIS
SEE ALSO HYPERSENSITIVITY. ATOPY
SEE ALSO HYPERSENSITIVITY. RESPIRATORY
HYPERSENSITIVITY
SEE ALSO HYPERSENSITIVITY. SENSITIZING ANTIBOOIES
HUMORAL
SEE ALSO HYPERSENSITIVITY. SERUM SICKNESS
SEE ALSO IMMUNOLOGY. ANTIGEN ANTIBODY REACTIONS,
IMMUNE COMPLEXES
POIHL 08805 15 0049 Regulation ol ventilation and
pulmonary circulation Pulmonary hypertension produced
by Dirotilaria immitis in the dog
P50HL 14153-07 0011 Johns Hopkins Lung Center
Chronic diseases ol airways - Allergy, airways reactivity
and asthma m human ragweed allergy
** P50HL-14153-07 0015 Johns Hopkins Lung Center-
Chronic diseases ol airways Kinins and human lung
P50HL 15092-07 0011 Immune and librotic response to
occupational environments Respiratory and immunologic
responses in coHee plant workers
P50HL- 15092-07 0012 Immune and librotic response to
occupational environments Longitudinal evaluation ol
workers exposed to cotton dust
P50HL 15389-07 0010 Pulmonary SCOR-Hypersensitivity
pneumonitis Clinical study -Pulmonary lesions due to non-
invasive aspergillosis
P50HL 1538907 0011 Pulmonary SCOR-Hypersensitivity
pneumonitis - Animal model-Hypersensitivity pneumonitis
in rabbits
POlHL-17382-05 0002 Chemical mediators of acute
pulmonary disorders - Chemical mediators and respiratory
mechanics in guinea pigs
POIHL 17382-05 0003 Chemical mediators of acute
pulmonary disorders - Chemical mediators relevant to
allergic reactions (human, guinea pigs)
ROlHL-18526-03 Kinins and the human lung
POIHL-19717-02 0037 Response of the lung to injury -
Catecholamines, prostaglandins and nucleotides in
pulmonary function (animals)
** R01HL-19777-03 Regulation of hypersensitivity in the lung
(rats, guinea pigs, rabbits, human)
R23HL-2 1089-02 Localization of mediators in dispersed
lung cells (guinea pigs, human)
ROlHL-23209-01 Autonomic receptors of the pulmonary
vasculature (mammals)
** ROlHL-23586-06 Pharmacologic control of hypersensitivity
phenomena (human)
HYPERSENSITIVITY, LYMPHOKINES
M POlHL-06370-17 Cardiopulmonary and renal pathology
research center
POlHL-0637017 0004 Cardiopulmonary and renal
pathology research center - Lymphocytes in graft rejection
and immune surveillance (human)
P50HL-19171-02 0007 Pulmonary SCOR-Lung injury by
childhood infections - Immunologic studies in models ol
lower respiratory tract infection (rodents)
** R01HL-19711-03 Lymphokines in pulmonary granulomas
(guinea pigs)
POlHL-19717-02 0016 Response ol the lung to injury -
The alveolar macrophage in elastase emphysema (guinea
pigs, hamsters)
POlHL-19717-02 0019 Response ol the lung to injury -
Animal model of fibrosing alveolitis (hamsters, guinea
pigs, rabbits)
** ROlHL-19732-03 Lymphokines in pulmonary
granulomatous inllammation (mice)
** R01HL-19819-03 Mitogen induced interstitial pneumonitis
(rabbits)
** R01HL-20095-03 Role of lymphokines and monocytes in
lung fibrosis (human, guinea pigs, rats)
** ROlHL-20104-03 Pulmonary granulomatous inflammations
(mice)
R23HL-21134-02 Immune function and fibrogenesis in
silicosis (guinea pigs)
HYPERSENSITIVITY, LYMPHOKINES, LEUKOTAXIC
FACTOR
P50HL-14217-08 0051 Specialized center of research in
thrombosis - Microcirculation section (bat. hamster)
ROlHL-16938-05 Effect of physical forces on blood (dogs,
human)
P50HL-18828-03 0005 Specialized center of research in
thrombosis - Platelet inflammatory factors in thrombosis
(human, guinea pig)
ROlHL-19732-03 Lymphokines in pulmonary
granulomatous inflammation (mice)
ROlHL-19741-03 Murine CRD-A model of chronic
pulmonary inflammation (mice, rats)
ROlHL-19777-03 Regulation of hypersensitivity in the lung
(rats, guinea pigs, rabbits, human)
** ROlHL-19795-03 Synthesis of anaphylatoxic and
leucotactic peptides (human)
(contd)
•Excludes routine methodology OR covers only general projects which preclude
"Oriented significantly to above subject.
Indexing at the specific level.
M Grant has subprajeds descnbing specific research aspects.
See Appendix for investigators name and grant number.
HYP
** ROlHL-19806-03 Chemotactic control of airway phagocytes
(human, rabbits)
ROlHL-20002-03 Pulmonary complications of viral
infections (children)
ROlHL-20104-03 Pulmonary granulomatous inflammations
(mice)
ROlHL-20220-03 Anaphylatoxins as inflammatory and
chemotactic agents (guinea pig, rabbit, human)
** ROlHL-22257-01 Leukokinesis enhancing factor and lung
Infections (human, rats)
** R23HL-22437-01 Leukotactic mediators in lung
inflammatory reactions (rats, rabbits, human)
HYPERSENSITIVITY, LYMPHOKINES, LYMPHOCYTE
TRANSFORMING FACTORS
POlHL-06314-17 0059 Immunologic mechanisms in
cardiovascular disease - Immunogenetic response to
streptococcal antigens in man
P50HL- 15389-07 0010 Pulmonary SCOR-Hypersensitivity
pneumonitis - Clinical study-Pulmonary lesions due to non-
invasive aspergillosis
HYPERSENSITIVITY, LYMPHOKINES,
MACROPHAGE AGGREGATION FACTOR
** POlHL-16769-05 0003 Pathobiologic and host defense
reactions in the lung - Pathobiologic mechanisms of
delayed sensitivity reactions in the lung (animals)
** POlHL-16769-05 0011 Pathobiologic and host defense
reactions in the lung - Core -Laboratory for biomedical
preparation (rabbits)
HYPERSENSITIVITY, LYMPHOKINES, MIGRATION
INHIBITORY FACTOR
ROlHL-01623-24 Antigens related to graft rejection
(rabbits, rats)
P50HL-15389-07 0010 Pulmonary SCOR-Hypersensitivity
pneumonitis - Clinical study-Pulmonary lesions due to non-
invasive aspergillosis
** POlHL-16769-05 0008 Pathobiologic and host defense
reactions in the lung - Pulmonary immunocytologic defense
mechanisms against bacteria (human, animals)
ROIHL-19234-03 Streptococci and heart Cell-mediated
cross-reaction (mice)
ROlHL-19732-03 Lymphokines in pulmonary
granulomatous inflammation (mice)
ROIHL- 198 73-03 Pulmonary responses to inhaled antigen
(rabbits, guinea pigs)
ROlHL-20104-03 Pulmonary granulomatous inflammations
(mice)
ROlHL-20125-02 Cyclic nucleotides and alveolar
macrophage activation (rabbits)
ROlHL-21047-01 Studies of coxsackievirus-induced
myocarditis in mice
R23HL-21212-02 Alveolar macrophage function in
Pseudomonas infection (dgs)
ROlHL-22029-02 Bronchopulmonary resistance to bacterial
infection (mice)
ROlHL-22456-01 Lipoproteins in bioregulation of the
immune response (mice, human)
ROlHL-23586-06 Pharmacologic control of hypersensitivity
phenomena (human)
HYPERSENSITIVITY, RESPIRATORY
HYPERSENSITIVITY
SEE ALSO HYPERSENSITIVITY, ALLERGENS AIRBORNE
SEE ALSO RESPIRATORY DISORDERS, PNEUMONITIS ALLERGIC
INTERSTITIAL
SEE ALSO RESPIRATORY DISORDERS, RESPIRATORY SYSTEM
TOXINS
POlHL-08805-15 0044 Regulation of ventilation and
pulmonary circulation - Neurochemical interactions in
respiratory control (human, dogs, goats)
P50HL-14136-07 0003 Pulmonary SCOR-Airways
obstructive diseases - Acute pediatric respiratory disease
and COLD
P50HL-14136-07 0009
obstructive diseases
P50HL-1413607 9006
obstructive diseases
P50HL-14153-07 0004
Pulmonary SCOR-Airways
Tuscon epidemiological study of
airways obstructive disease (human)
P50HL-14136-07 0016 Pulmonary SCOR-Airways
obstructive diseases - Environmental factors in airways
obstructive diseases (human)
P50HL-14136-07 9005 Pulmonary SCOR-Airways
obstructive diseases - Clinical core
Pulmonary SCOR-Airways
Pediatric lung function core
Johns Hopkins Lung Center-
Chronic diseases of airways - Macrophage enzymes in lung
injury, inflammation and repair (rabbit)
P50HL-14I53-07 0018 Johns Hopkins Lung Center-
Chronic diseases of airways - Pulmonary function core
P50HL-1 5092-07 Immune and fibrotic response to
occupational environments
P50HL-15092-07 0005 Immune and fibrotic response to
occupational environments - Respiratory and immunologic
evaluation of toluene diisocyanate exposure (human)
P50HL-15092-07 0011 Immune and fibrotic response to
occupational environments - Respiratory and immunologic
responses in coffee plant workers
P50HL-15092-07 0012 Immune and fibrotic response to
occupational environments Longitudinal evaluation of
workers exposed to cotton dust
292
P50HL-15092-07 0014 Immune and fibrotic response to
occupational environments - Clinical immunology core
resource
P50HL-15389-07 Pulmonary SCOR-Hypersensitivity
pneumonitis
P50HL-15389-07 0001 Pulmonary SCOR-Hypersensitivity
pneumonitis - Clinical studies of hypersensitivity
pneumonitis
P50HL-15389-07 0008 Pulmonary SCOR-Hypersensitivity
pneumonitis - Milwaukee patient study-Hypersensitivity
pneumonitis
P50HL15389-07 0010 Pulmonary SCOR-Hypersensitivity
pneumonitis - Clinical study-Pulmonary lesions due to non-
invasive aspergillosis
P50HL-15389-07 0011 Pulmonary SCOR-Hypersensitivity
pneumonitis - Animal model-Hypersensitivity pneumonitis
in rabbits
P50HL 15389-07 0013 Pulmonary SCOR-Hypersensitivity
pneumonitis - Animal model-Pulmonary mycotoxicosis
(rabbit, guinea pig)
P50HL- 15389-07 0014 Pulmonary SCOR-Hypersensitivity
pneumonitis - Fractionation and characterization of pigeon
antigens
P50HL-15389-07 0015 Pulmonary SCOR-Hypersensitivity
pneumonitis - Fractionation and characterization of
thermophilic Actinomyccte antigens
P50HL-1 5389-07 0017 Pulmonary SCOR-Hypersensitivity
pneumonitis - Immunology core (human)
POlHL-16769-05 0003 Pathobiologic and host defense
reactions in the lung - Pathobiologic mechanisms of
delayed sensitivity reactions in the lung (animals)
ROlHL-16920-02 Proteases in normal and immunologically
injured lung (guinea pigs, rabbits)
POlHL-17382-05 Chemical mediators of acute pulmonary
disorders
POlHL-17382-05 0002 Chemical mediators of acute
pulmonary disorders - Chemical mediators and respiratory
mechanics in guinea pigs
POlHL-17382-05 0003 Chemical mediators of acute
pulmonary disorders ■ Chemical mediators relevant to
allergic reactions (human, guinea pigs)
P50HL-191 56-02 0005 Pulmonary SCOR -Chronic diseases
of airways - Vagal receptors in the airway-Epithelial injury
and antigen (dog, cat, rabbit)
P50HL-191 70-02 Harvard pulmonary SCOR-Chronic
diseases of the airways
P50HL-191 70-02 0003 Harvard pulmonary SCOR-Chronic
diseases of the airways - Mechanisms of bronchial
reactivity to acute and chronic airway challenge (dog)
P50HL-191 70-02 0005 Harvard pulmonary SCOR-Chronic
diseases of the airways - Pulmonary toxicology of plastics
intermediates and pyrolysis products (animal)
P50HL-191 70-02 0006 Harvard pulmonary SCOR-Chronic
diseases of the airways • Mechanism of overdistension
(human, animal)
P50HL-191 70-02 0007 Harvard pulmonary SCOR-Chronic
diseases of the airways - Therapy effect on ain«ay
obstruction in acute asthma (human)
ROlHL-197 11-03 Lymphokines in pulmonary granulomas
(guinea pigs)
ROlHL-19732-03 Lymphokines in pulmonary
granulomatous inflammation (mice)
ROlHL-19733-03 Absorption of antigen through inflamed
lungs (rabbits)
ROlHL-19741-03 Murine CRD-A model of chronic
pulmonary inflammation (mice, rats)
ROlHL-19746-03 Proliferation and differentiation of
alveolar macrophages (mice, hamsters)
ROlHL-19760-01 Cellular immune responses of the lung
(mice, guinea pigs)
ROlHL-19777-03 Regulation of hypersensitivity in the lung
(rats, guinea pigs, rabbits, human)
ROlHL-19795-03 Synthesis of anaphylatoxic and
leucotactic peptides (human)
ROlHL-19806-03
(human, rabbits)
ROlHL-19819-03
Chemotactic control of airway phagocytes
Mitogen induced interstitial pneumonitis
(rabbits)
ROlHL-20063-03 Pathogenesis of pulmonary mycoplasma
infections (guinea pigs, mice)
** ROlHL-20095-03 Role of lymphokines and monocytes in
lung fibrosis (human, guinea pigs, rats)
ROlHL-20104-03 Pulmonary granulomatous inflammations
(mice)
** ROlHL-20220-03 Anaphylatoxins as inflammatory and
chemotactic agents (guinea pig, rabbit, human)
** ROlHL-21565-02 Pathogenesis of inflammatory lung injury
(rats, rabbits)
ROlHL-22021-01 Asthma in families- Behavior analysis of
family interaction pattern
ROlHL-23209-01 Autonomic receptors of the pulmonary
vasculature (mammals)
HYPERSENSITIVITY, RESPIRATORY
HYPERSENSITIVITY, ASTHMA
SEE ALSO RESPIRATORY DISORDERS, BRONCHOSPASM
POlHL-06285-18 0181 Cardiovascular-respiratory
physiology and biochemistry - Regulation of respiration-
Role of vagus nerve (dogs)
** POlHL-06285-18 0188 Cardiovascular-respiratory
physiology and biochemistry - Physiology and pharmacology
in regulation of airways-hyperirritability (animals)
HYP
POlHL-07896-15 0053 Environmental biomedical research
program - Thermoregulation in asthmatics
ROlHL-10009-13 Regional lung function in man
ROlHL-10622-12 Volumes and compliance of pulmonary
circulation (human, dogs)
POlHL-12373-10 0012 Cardiopulmonary physiology and
pathophysiology - Biochemistry of the sympathetic nervous
system (rats, rabbits, pigeons)
ROlHL-12530-10 Emphysema-Respiratory function in
disease (human, dogs, rats)
P50HL-14136-07 0009 Pulmonary SCOR-Airways
obstructive diseases - Tuscon epidemiological study of
airways obstructive disease (human)
P50HL- 14 153-07 Johns Hopkins Lung Center-Chronic
diseases of airways
P50HL-14153-07 0011 Johns Hopkins Lung Center-
Chronic diseases of airways Allergy, airways reactivity
and asthma in human ragweed allergy
P50HL-14153-07 0012 Johns Hopkins Lung Center-
Chronic diseases of airways - Aspirin intolerance in
reversible lung disease (human)
P50HL-14153-07 0013 Johns Hopkins Lung Center-
Chronic diseases of airways - Pulmonary mechanics and
mediators of allergic reactions (guinea pigs, human)
P50HL-14153-07 0014 Johns Hopkins Lung Center-
Chronic diseases of airways - Mediator release in asthma
(human)
P50HL-14153-07 0015 Johns Hopkins Lung Center-
Chronic diseases of airways - Kinins and human lung
P50HL-14153-07 0016 Johns Hopkins Lung Center-
Chronic diseases of airways - Airways defense mechanisms
(dogs)
P50HL-15092-07 0005 Immune and fibrotic response to
occupational environments Respiratory and immunologic
evaluation of toluene diisocyanate exposure (human)
P50HL-15092-07 0011 Immune and fibrotic response to
occupational environments - Respiratory and immunologic
responses in coffee plant workers
P01HL15194-07 0024 Pathophysiology of
cardiopulmonary dysfunction - Distribution of ventilation-
Airflow limitation in COLD (human)
ROlHL-15677-06 Autonomic nervous system function In
bronchial asthma (human, guinea pig, rabbit)
ROlHL-16524-02 Selective inhibitors of prostaglandin
biosynthesis (dogs)
POlHL-16878-05 0001 Control of ventilation in health
and disease - Ability of asthmatics to detect added
resistive and elastic loads
ROlHL-17322-04 Functional characteristics of smooth
muscle isolated from lung (animals)
POlHL-1 7382-05 0001 Chemical mediators of acute
pulmonary disorders - Chemical mediators and respiratory
mechanics in humans
POlHL-17731-04 0006 Physiological basis of pulmonary
disease - Ventilation-perfusion ratios (human, dogs)
ROlHL-1777604 Pulmonary mucus transport in
obstructive lung diseases (human)
ROlHL-17873-04 Pathophysiology of exercise-induced
asthma (human)
ROlHL-18070-04 Regulation of intrapulmonary airways
and vessels (human, animals)
ROlHL-18077-04 Smooth muscle cell organization and
Ca20 concentration control (chickens)
ROlHL-18632'02 Epidemiologic study of chronic lung
disease
ROlHL-19062-03 Pharmacologic control of mast cell
phosphodiesterase (human, rats)
ROlHL-191 15-02 Hormonal control of tracheobronchial
cyclic AMP (rats, guinea pigs)
ROlHL-191 18-03 Measurement of airways mechanics
(human, dog)
P50HL-19156-02 Pulmonary SCOR-Chronic diseases of
airways
P50HL-19156-02 0001 Pulmonary SCOR-Chronic diseases
of airways - Irritability of airways induced by epithelial
damage in healthy subjects (human)
P50HL-19156-02 0004 Pulmonary SCOR-Chronic diseases
of airways - Interactions between mast cells, mediators
and nerves in canme asthma
P50HL-19157-02 0011 Studies in cystic fibrosis and
bronchiolitis - Pathogenesis of bronchiolitis (children)
P50HL-19170-02 0006 Harvard pulmonary SCOR-Chronic
diseases of the airways - Mechanism of overdistension
(human, animal)
P50HL-19170-02 0007 Harvard pulmonary SCOR-Chronic
diseases of the airways Therapy effect on airway
obstruction in acute asthma (human)
P50HL-19171-02 0004 Pulmonary SCOR-Lung injury by
childhood infections - Long-term effects of respiratory
infections in early childhood
POlHL-19717-02 0009 Response of the lung to injury -
Time-dependent mechanical properties of lung connective
tissues (hamsters)
ROlHL-20122-02 Operational mechanisms of airway
receptors (dogs, pigs)
ROlHL-20184-02 Desensitization of tracheal muscle to
isoproterenol (rats, rabbits)
ROlHL-20347-02 Bolus-response measurement of lung
function (human)
ROlHL-20675-02 Alveolar macrophage function in man
ROlHL-20783-02 Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
(contd)
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
••Oriented significantly to above subject.
IVl Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number
HYP
•• R23HI 20968 02 Respiratory ttllure Control and muscle
dysfunction (human)
•* ROIHL 20989 01 Pathophysiology ot bronchial asthma
(shaep. dots)
R01HL2U2602 tuercise induced bronchospasm in
children
R23HL2U5002 Rejulation of airway mucous glands and
ion transport (dogs, ascaris)
R23HL2119902 Sound transmission in lung (dog)
** ROIHL 21318 02 Mechanisms of emotions' asthma
triggering effect (human)
" POIHL 21584 02 0006 Respiratory mechanics in normal
and abnormal states Respiratory mechanics in health and
disease (human, pigs)
•* ROIHL 2182901 Etiology of obstructive airway disease in
children (also monkeys)
•* R23HL-2201101 Adrenergic receptor cyclase system in
sensitized lung (rats, guinea pigs)
** ROIHL 2202101 Asthma in families ■ Behavior analysis ot
family interaction pattern
** ROlHL-2202601 Endogenous prostaglandins in asthma
" ROlHL-2206501 Intractability, medication, and coping
styles in asthma (human)
** ROIHL 2241501 Mechanisms responsible for disease
severity in asthma (human)
ROlHL-22555-01 Structure and function of platelet
activating factor (rabbits, human)
R23HL-2281801 Biosynthesis of human respiratory
mucous glycoprotein (also dog)
** ROlHL-2292401 The airway mucosal barrier (guinea pigs)
** R23HL-2293201 Effect of carbon dioxide on local gas
exchange (dogs)
•• ROlHL-23631-01 Immunogenetic factors in allergic
respiratory diseases (human)
** N01HR-62935-02 Histocompatibility antigens-Evolution of
respiratory hypersensitivity (human)
** NOlHR-7297201 Self-management for asthmatic children
** N01HR-72973-01 Health education and attitudes of family
toward asthmatic children
** NOlHR-72974-01 Self-management systems for asthmatic
children
HYPERSENSITIVITY, RESPIRATORY
HYPERSENSITIVITY, HAY FEVER
•* P50HL-14153-07 0011 Johns Hopkins Lung Center-
Chronic diseases of airways - Allergy, airways reactivity
and asthma in human ragweed allergy
HYPERSENSITIVITY, SENSITIZATION PASSIVE
SEE ALSO HYPERSENSITIVITY, SKIN SENSITIZING ANTIBODY
ROlHL-19819-03 Mitogen induced interstitial pneumonitis
(rabbits)
HYPERSENSITIVITY, SENSITIZING ANTIBODIES
HUMORAL
SEE ALSO HYPERSENSITIVITY. SKIN SENSITIZING ANTIBODY
P50HL-15389-07 0012 Pulmonary SCOR-Hypersensitivity
pneumonitis - Animal model-lmmunologic lung disease in
guinea pigs
P01HL18646-03 0004 Studies basic to heart
transplantation ■ Presensitization -Detection, incidence and
clinical significance
P01HL18646-03 0006 Studies basic to heart
transplantation - Reduction or elimination of existing
presensitization (human, animals)
R01HL19819-03 Mitogen induced interstitial pneumonitis
(rabbits)
HYPERSENSITIVITY, SENSITIZING ANTIBODIES
NON-HUMORAL
SEE ALSO HYPERSENSITIVITY. TRANSFER FACTOR
(HYPERSENSITIVITY)
ROlHL-19806-03 Chemotactic control of airway phagocytes
(human, rabbits)
HYPERSENSITIVITY, SERUM SICKNESS
P01HL-16411-04 0004 Blood systems in coagulation and
vessel disease ■ Platelets reactions in vascular injury
(human, animals)
HYPERSENSITIVITY, SKIN SENSITIZING
ANTIBODY
P50HL-15389-07 0011 Pulmonary SCOR-Hypersensitivity
pneumonitis - Animal model-Hypersensitivity pneumonitis
in rabbits
HYPERSENSITIVITY, TOXIC REACTIONS AND
MECHANISMS IN HYPERSENSITIVITY
SEE ALSO HYPERSENSITIVirr. ANAPHYLAXIS
P50HL-14153-07 0012 Johns Hopkins Lung Center-
Chronic diseases of airways - Aspirin intolerance in
reversible lung disease (human)
P50HL-14153-07 0014 Johns Hopkins Lung Center-
Chronic diseases of airways - Mediator release in asthma
(human)
P50HL- 15389-07 0009 Pulmonary SCOR-Hypersensitivity
pneumonitis - Clinical studies -Pulmonary mycotoxicosis
P50HL-15389-07 0011 Pulmonary SCOR-Hypersensitivity
pneumonitis - Animal model -Hypersensitivity pneumonitis
in rabbits
P50HL 15389-07 0012 Pulmonary SCOR-Hypersensitivity
pneumonitis - Animal model-lmmunologic lung disease in
guinea pigs
393
•• P50HL 15389 07 0013 Pulmonary SCOR Hypersensitivity
pneumonitis Animal model Pulmonary mycotoxicosis
(rabbit, guinea pig)
HYPERSENSITIVITY, TRANSFER FACTOR
(HYPERSENSITIVITY)
P50HL 15389 07 0011 Pulmonary SCOR Hypersensitivity
pneumonitis Animal model Hypersensitivity pneumonitis
in rabbits
•* POIHL 16769 05 0008 Pathobiologic and host defense
reactions in the lung Pulmonary immunocytologic defense
mechanisms against bacteria (human, animals)
ROIHL 19873 03 Pulmonary responses to inhaled antigen
(rabbits, guinea pigs)
HYPERSENSITIVITY DESENSITIZATION
SEE ALSO IMMUNITY, IMMUNOSUPPRESSION
ROIHL 19423 03 Catecholamine action on the heart (cats,
rats)
ROIHL 19711 03 Lymphokines in pulmonary granulomas
(guinea pigs)
ROIHL 19777 03 Regulation of hypersensitivity in the lung
(rats, guinea pigs, rabbits, human)
R01HL21565-02 Pathogenesis of inflammatory lung injury
(rats, rabbits)
** ROlHL-23586 06 Pharmacologic control of hypersensitivity
phenomena (human)
HYPERSENSITIVITY PNEUMONITIS
SEE RESPIRATORY DISORDERS, PNEUMONITIS ALLERGIC
INTERSTITIAL
HYPERSENSITIVITY TESTS
SEE ALSO TISSUE COMPATIBILITY-TRANSPLANT.
HISTOCOMPATIBILITY TYPING
P50HL-15389-07 0008 Pulmonary SCOR-Hypersensltivify
pneumonitis - Milwaukee patient study-Hypersensitivity
pneumonitis
P50HL 15389-07 0017 Pulmonary SCOR -Hypersensitivity
pneumonitis Immunology core (human)
HYPERSENSITIVITY TESTS SKIN
SEE ALSO HYPERSENSITIVITY. ANAPHYLAXIS. SHVKARTZMAN
PHENOMENON
SEE ALSO HYPERSENSITIVITY. SKIN SENSITIZING ANTIBODY
P50HL-1882803 0006 Specialized center of research in
thrombosis Etiology and pathogenesis of atherosclerosis
(rabbit, monkey, rat, human)
ROlHL-224 15-01 Mechanisms responsible for disease
severity in asthma (human)
HYPERSPLENISM
SEE BLOOD AND RE DISORDERS, SPLENIC DISORDERS,
SPLENOMEGALY
HYPERTENSIN
SEE PEPTIDES, VASOACTIVE PEPTIDES, ANGIOTENSIN
HYPERTENSINOGEN
SEE PEPTIDES, VASOACTIVE PEPTIDES, ANGIOTENSINOGEN
HYPERTENSION
SEE ADRENAL GLANDS DISORDERS, ADRENAL HYPERTENSION
SEE CARDIOVASCULAR DISORDERS, HYPERTENSION
(SYSTEMIC)
SEE CARDIOVASCULAR DISORDERS, HYPERTENSION
(SYSTEMIC), NEUROGENIC HYPERTENSION
SEE KIDNEY-CIRCULATORY DISORDERS, RENAL
HYPERTENSION
SEE KIDNEY-CIRCULATORY DISORDERS. RENOPRIVAL
HYPERTENSION
SEE LIVER CIRCULATORY DISORDERS, PORTAL
HYPERTENSION
SEE PREGNANCY TOXEMIAS AND HYPERTENSION
SEE RESPIRATORY CIRCULATORY DISORDERS, PULMONARY
HYPERTENSION
HYPERTHERMIA
SEE TEMPERATURE (BODY), FEVER
HYPERTHERMIA INDUCED
SEE TEMPERATURE (BODY), HYPERTHERMIA INDUCED
HYPERTHYROIDISM
SEE THYROID GLAND DISORDERS, HYPERTHYROIDISM
HYPERTRICHINOSIS
SEE DISEASES. SIGNS-SYMPTOMS. HIRSUTISM
HYPERTROPHIC MYOCARDIOPATHY
SEE HEART DISORDERS. MYOCARDIAL DISORDERS,
HYPERTROPHIC MYOCARDIOPATHY
HYPERTROPHY
SEE GROWTH ABNORMAL. HYPERTROPHY
HYPERURICEMIA
SEE PURINES-PYRIMIDINES METABOLISM ERRORS,
HYPERURICEMIA
HYPERURICEMIA LOWERING DRUGS
SEE PURINES-PYRIMIDINES METABOLISM ERRORS, GOUT
DRUGS
HYPERVENTILATION ACTIVE
SEE RESPIRATORY FUNCTION. HYPERPNEA
HYP
HYPERVENTILATION PASSIVE
SEE RfSPIRAIORY ASSIST AND OXYGEt* ADMINISTRATION,
HYPrRVINIIlAIION PASSIVf
HYPERVISCOSITY SYNDROME
SEE BLOOD PROfdNS OISORDLRS. HYPERVISCOSIIY
SYNDROME
HYPERVOLEMIA
SEE CARDIOVASCULAR DISORDERS, HYPERVOLEMIA
HYPNOSIS
SEE PSYCHOLOGY. SUGGESTION. HYPNOSIS
HYPNOTICS AND SEDATIVES
SEE PSYCHOPHARMACOLOGICAL AGENTS. HYPNOTICS AND
SEDATIVES
HYPOALDOSTERONISM
SEE ADRENAL GLANDS DISORDERS. HYPOALDOSTERONISM
HYPOBETALIPOPROTEINEMIA
SEE METABOLIC DISORDERS INBORN.
HYPOLIPOPROTEINEMIAS FAMILIAL.
ABETALIPOPROTEINEMIA
HYPOCAPNIA
SEE RESPIRATORY GAS LEVELS. HYPOCAPNIA
HYPOCHOLESTEREMIA
SEE LIPIDS BLOOD. HYPOCHOLESTEREMIA
HYPOCHROMIC MICROCYTIC ANEMIA
SEE BLOOD AND RE DISORDERS. ANEMIA HYPOCHROMIC
MICROCYTIC
HYPOCHROMISM (CHEMISTRY)
SEE OPTICS. CHROMOPHORE*
HYPOCUPREMIA
SEE METAL DISORDERS AND IMBALANCES. HYPOCUPREMIA
HYPOGLYCEMIA
SEE CARBOHYDRATE BALANCE, HYPOGLYCEMIA
HYPOGLYCEMIC AGENTS
SEE CARBOHYDRATE BALANCE, HYPOGLYCEMIC AGENTS
HYPOGONADISM
SEE REPRODUCTIVE AND SEX DEVELOPMENT DISORDERS,
HYPOGONADISM
HYPOIMMUNITY
SEE IMMUNITY, IMMUNOLOGICAL UNRESPONSIVENESS
HYPOKALEMIA
SEE BODY FLUID BALANCE, IONIC, HYPOKALEMIA
HYPOLIPOPROTEINEMIA
SEE LIPOPROTEINS BLOOD, HYPOLIPOPROTEINEMIA
HYPOMAGNESEMIA
SEE METAL DISORDERS AND Ifl/IBALANCES, MAGNESIUM
DEFICIENCY
HYPONATREMIA
SEE BODY FLUID BALANCE, IONIC, HYPONATREMIA
HYPOPHOSPHATASIA
SEE METABOLIC DISORDERS INBORN, HYPOPHOSPHATASIA
HYPOPHRENIC (TROPHOTROPIC) STATE
SEE PSYCHIC ACTIVITY LEVEL, TROPHOTROPIC STATE
HYPOPHYSECTOMY
SEE PITUITARY REMOVAL
HYPOPHYSIS
SEE PITUITARY GLAND
HYPOPITUITARY DWARFISM
SEE SKELETAL DISORDERS, BONE DEVELOPMENT, DWARFISM,
PITUITARY
HYPOPLASTIC ANEMIA CONGENITAL
SEE BLOOD AND RE DISORDERS, ANEMIA APLASTIC
CONGENITAL
HYPOPROCONVERTINEMIA
SEE BLOOD COAGUUTION DISORDERS, FACTOR VII
DEFICIENCY
HYPOPROTEINEMIA
SEE BLOOD PROTEINS DISORDERS, HYPOPROTEINEMIA
HYPOPROTHROMBINEMIAS
SEE BLOOD COAGULATION DISORDERS,
HYPOPROTHROMBINEMIAS
HYPORENINEMIC HYPOALDOSTERONISM
SEE ADRENAL GUNDS DISORDERS, HYPOALDOSTERONISM.
HYPORENINEMIC
HYPOSENSITIZATION FOR HYPERSENSITIVITY
SEE HYPERSENSITIVITY DESENSITIZATION
HYPOTENSION
SEE CARDIOVASCULAR DISORDERS, HYPOTENSION
HYPOTENSION, POSTURAL (ORTHOSTATIC)
SEE CARDIOVASCULAR DISORDERS, HYPOTENSION POSTURAL
(contd)
•Excludes routine methodology OR covers only general projects which preclude
**Onented significantly to above subject.
indexing at the specific level.
M Grant has subprojerts describing specific research aspects.
See Appendix for investigator's name and grant number.
HYP
HYPOTENSIVE PEPTIDES
SEE PEPTIDES, VASOACTIVE PEPTIDES, HYPOTENSIVE
PEPTIDES
HYPOTHALAMO-HYPOPHYSEAL SYSTEM
(HORMONES)
SEE PITUITARY-DIENCEPHALON (HORMONES)
HYPOTHALAMUS
SEE BRAIN, HYPOTHALAMUS
HYPOTHERMIA
SEE TEMPERATURE (BODY), HYPOTHERMIA
HYPOTHERMIA, ANESTHETIC
SEE SENSORY DEPRESSION, ANESTHESIA, REFRIGERATION
HYPOTHERMIA INDUCED
SEE TEMPERATURE (BODY), HYPOTHERMIA INDUCED
HYPOTHYROIDISM
SEE THYROID GLAND DISORDERS, HYPOTHYROIDISM
HYPOVENTILATION, RESPIRATORY (GENERAL)
SEE RESPIRATORY FUNCTION, HYPOVENTILATION (GENERAL)
HYPOVENTILATION FROM RESPIRATORY CENTER
DYSFUNCTION
SEE RESPIRATORY FUNCTION, HYPOVENTILATION,
RESPIRATORY CENTER DYSFUNCTION
HYPOVENTILATION NOCTURNAL
SEE RESPIRATORY FUNCTION, HYPOVENTILATION,
RESPIRATORY CENTER DYSFUNCTION
HYPOVITAMINOSIS A
SEE NUTRITIONAL ABNORMALITIES, HYPOVITAMINOSIS A
HYPOVITAMINOSIS C
SEE NUTRITIONAL ABNORMALITIES, HYPOVITAMINOSIS C
HYPOVITAMINOSIS E
SEE NUTRITIONAL ABNORMALITIES, HYPOVITAMINOSIS E
HYPOVITAMINOSIS K
SEE NUTRITIONAL ABNORMALITIES, HYPOVITAMINOSIS K
HYPOVOLEMIA
SEE CARDIOVASCUUR DISORDERS, HYPOVOLEMIA
HYPOXANTHINE
SEE PURINES, HYPO)(ANTHINE
HYPOXANTHINE
PHOSPHORIBOSYLTRANSFERASE
SEE GLYCOSYLTRANSFERASES, IMP:PYROPHOSPHATE
PHOSPHORIBOSYLTRANSFERASE
HYPOXIA
SEE RESPIRATORY GAS LEVELS, HYPOXIA
HYPOXIA, RESPIRATORY
SEE RESPIRATORY GAS LEVELS, HYPOXIA, RESPIRATORY
HYPOXIA FETAL
SEE RESPIRATORY GAS LEVELS, HYPOXIA FCTAL
HYPOXIA NEONATORUM
SEE RESPIRATORY GAS LEVELS, HYPOXIA NEONATORUM
HYSTERECTOMY
SEE REPRODUCTIVE SYSTEM SURGERY FEMALE,
HYSTERECTOMY
I ANTIGENS (BLOOD GROUP)
SEE BLOOD GROUPS ANTIGENS, II ANTIGENS
l-CELL DISEASE
SEE METABOLIC DISORDERS INBORN,
MUCOPOLYSACCHARIDOSIS, l-CELL DISEASE
IDENTIFICATION OF VIRUSES
SEE MICROBIAL IDENTIFICATION AND CLASSIFICATION, VIRAL
TYPING AND IDENTIFICATION
IDIOPATHIC HIRSUTISM
SEE DISEASES, SIGNS-SYMPTOMS, HIRSUTISM
L-IDURONIC ACID
SEE SUGAR ACIDS, HEXURONIC ACIDS, L-IDURONIC ACID
IGA SECRETORY
SEE IMMUNOLOGY, SECRETORY (ANTIBODY) (FACTOR)
SYSTEM
II ANTIGENS
SEE BLOOD GROUPS ANTIGENS, II ANTIGENS
ILEAL BYPASS
SEE GASTROINTESTINAL SURGERY, ILEAL BYPASS-ILEECTOMY
ILEECTOMY
SEE GASTROINTESTINAL SURGERY, ILEAL BYPASS-ILEECTOMY
ILEUM
SEE GASTROINTESTINAL SYSTEM, INTESTINES, SMALL
INTESTINE, ILEUM
lUAC ARTERY
SEE CARDIOVASCULAR SYSTEM, ARTERIES, ILIAC ARTERY
294
IMAGE AND WAVESHAPE PROCESSING
ANALYSIS AND DISPLAY
SEE OPTICS, IMAGE PROCESSING ANALYSIS AND DISPLAY*
IMAGE ENHANCEMENT
SEE OPTICS, IMAGE ENHANCEMENT*
IMAGING-VISUALIZATION (GENERAL)
SEE OPTICS, IMAGING-VISUALIZATION (GENERAL)*
IMIDATES
** P60HL-20985-01 0006 Northern California sickle cell
center - Antisickling properties of imidoesters (human, rats)
** R23HL 21129-02 The antisickling effects of imidoesters
IMIDAZOLEDIONES, HYDANTOINS,
DANTROLENE
P01HL-113S1-12 0011 Cellular and molecular
mechanisms of myocardial function - Comparative
contractile tissue studies (animals)
POlHL-12738-10 0109 Physiologic pharmacology and its
clinical applications - Effects of calcium blockers on
skeletal and cardiac muscle (cats)
IMIDAZOLEDIONES, HYDANTOINS,
DIPHENYLHYDANTOIN
R01HL-07776-15 Sudden death and cardiac arrhythmias
(human, dogs, cats)
Physiologic pharmacology and its
Clinical pharmacology of cardioactive
Physiologic pharmacology and Its
Blood superfused cardiac fibers
POlHL-12738-10 0001
clinical applications
drugs (human)
POlHL-12738-10 0107
clinical applications
(dogs)
ROlHL-13666-06 Pharmacology of genesis of cardiac
rhythmicity (rats, cats)
ROlHL-14102-07 Human physiology at 5360 meters-
Mountain environment
P01HL-14388-07 0234 Regulation of the circulation in
pathological states - Effects of antiarrhythmic drugs on the
autonomic system (dogs)
R01HL-14832-06 Myocardial cells-AutonomIc and rhythmic
mechanisms (chick embryo, rats)
R01HL-16052-05 Cardiac glycosides-Mechanism of
inotropic action (dogs)
ROIHL- 160 76-06 Electrophysiology of fibrillation and
defibrillation (human)
P50HL-17648-04 0014 Study of ischemic heart disease -
Antidysrhythmic drugs and mammalian cardiac Purklnje
fibers (sheep, dog)
R01HL-21672-01 Antiarrhythmic drug action on VMAZ of
cardiac cells
ROlHL-21742-01 Frequency-dependent drug actions in
cardiac muscle (rabbits)
ROlHL-22568-01 pH effect in heart cells-Influence of
cardiac drugs (tissue culture, rats)
ROlHL-22862-01 CNS-mediated effects of antiarrhythmic
drugs (dogs)
IMIDAZOLES
SEE ALSO CYCLIC AMINO ACIDS, HISTIOINE
SEE ALSO PURINES
ROlHL-16674-05 Airborne metals and lung permeability
(bullfrogs, rats)
IMIDAZOLES, CATAPRES
ROlHL-07835-17 Experimental hypertension and renal
circulation (rats, rabbits)
RaiHL-10951-11 Neural control of the heart (dogs, rats)
POlHL-12738-10 0042 Physiologic pharmacology and its
clinical applications - Centrogenic cardiac arrhythmias
(cats)
ROlHL-13187-09 Central neural control of cardiovascular
function (cats)
POlHL-17871-04 0009 Kidney, sodium, cardiac output,
arterioles and hypertension - Kidney, sodium, cardiac
output, arterioles and hypertension
P50HL-18323-04 0043 SCOR hypertension center -
Pharmacology-Renin-aldosterone mechanisms in essential
hypertension (human)
ROlHL-20194-01 Brain catecholamines in control of blood
pressure (rats)
R01HL-22868-01 Presynaptic regulatory mechanisms in
hypertension (rats, dogs)
IMIDAZOLES, HISTAMINE
POlHL-031 74-23 0009 Mechanisms of acute vascular
reaction to injury - Mast cell lipid interaction (human, rats)
ROlHL-05883-18 0001 Reflex control of resistance and
capacitance vessels - Naturally occurring vasoactive
substances and the vascular neuroeffectors (dog)
POlHL-06285-18 0188 Cardiovascular-respiratory
physiology and biochemistry - Physiology and pharmacology
in regulation of airways-hyperirritability (animals)
POlHL-06285-18 0189 Cardiovascular-respiratory
physiology and biochemistry - Mucociliary clearance (cats,
dogs)
POlHL-07896-15 0043 Environmental biomedical research
program - Effect of hyperbaric oxygen on the lung (human,
rabbits)
POlHL-08805-15 0048 Regulation of ventilation and
pulmonary circulation - Permeability of alveolo-Capillary
membrane in normal pulmonary hypertensive lung
The cardiac histamine receptor (rabbits.
Localization of airways obstruction and
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
**Otiented significantly to above subject
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number
IMI
ROlHL-08977-14 Quantitation of flow and solute flux in
microvessels (cats, rats)
POlHL-10342-13 0024 The integrated function of
respiration and circulation - Cytochrome P450 and
physiological response to hypoxia (rats)
P01HL10342-13 0028 The integrated function of
respiration and circulation - Mediator release,
hemodynamics and respiratory function in anaphylaxis
(dogs)
ROlHL-10897-12 Effects of hormones on cardiac
electrogenesis (rabbits, guinea pigs, dogs)
ROlHL-12421-10 Pathophysiology of circulatory shock
(dogs, baboons)
ROlHL-12677-10 Surgical physiologic studies of isolated
kidneys (dogs, rats)
POIHL 12738-10 0109 Physiologic pharmacology and its
clinical applications - Effects of calcium blockers on
skeletal and cardiac muscle (cats)
ROlHL-13315-08 Disposition of vasoactive hormones in
mammalian lung (rats, rabbits, human)
ROlHL-13323-08 Intrarenal pressure and renal function
(human, dogs)
P50HL-14153-07 0013 Johns Hopkins Lung Center--
Chronic diseases of airways - Pulmonary mechanics and
mediators of allergic reactions (guinea pigs, human)
P50HL-14153-07 0016 Johns Hopkins Lung Center-
Chronic diseases of airways - Airways defense mechanisms
(dogs)
POlHL-14388-07 0179 Regulation of the circulation in
pathological states - Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
POlHL-14388-07 0187 Regulation of the circulation in
pathological states - Histamine and circulatory control
POIHL-14985-07 0007 Adaptation to hypoxia - Control of
pulmonary circulation, histamine and the sympathetics
(animals)
POlHL-14985-07 0010 Adaptation to hypoxia - Pulmonary
mast cell (animals)
ROlHL-15677-06 Autonomic nervous system function in
bronchial asthma (human, guinea pig, rabbit)
P01HL161 17-05 0008 Ion movements and membranes in
cardiovascular control - Arterial smooth muscle calcium
fluxes and contractility (rabbits)
ROlHL-16240-05
guinea pigs)
R01HL16463-05
responses
ROlHL-17355-04. Pulmonary vascular adjustments In
circulatory collapse (dogs, rats)
POlHL-17382-05 Chemical mediators of acute pulmonary
disorders
P01HL-17382-0S 0001 Chemical mediators of acute
pulmonary disorders - Chemical mediators and respiratory
mechanics in humans
POIHL- 17382-05 0002 Chemical mediators of acute
pulmonary disorders - Chemical mediators and respiratory
mechanics in guinea pigs
POlHL-17382-05 0003 Chemical mediators of acute
pulmonary disorders - Chemical mediators relevant to
allergic reactions (human, guinea pigs)
ROlHL-17711-05 Mechanism of hypoxic regulation of lung
circulation (rats, cats, guinea pigs)
POlHL-17731-04 0006 Physiological basis of pulmonary
disease - Ventilation-perfusion ratios (human, dogs)
ROlHL-17768-04 Development of collateral ventilation
(dogs, fish, horses)
ROlHL-18070-04 Regulation of intrapulmonary airways
and vessels (human, animals)
ROlHL-18272-03 Heart adenyl cyclase complex (beef
heart)
ROlHL-18607-03 Metabolic and drug studies on
experimental fat embolism (mice)
ROlHL-18711-03 Electrophysiology of heart cells (rats,
chicks)
R01HL18936-02
studies (rat)
ROlHL-19039-03
model (dogs)
P50HL-19153-02 0002 SCOR -Pulmonary edemas-Eitology,
pathogenesis - Lung fluid dynamics-Classical mediators
and their inhibitors (sheep)
P50HL-19156-02 0001 Pulmonary SCOR-Chronic diseases
of airways - Irritability of airways induced by epithelial
damage in healthy subjects (human)
P50HL-19156-02 0005 Pulmonary SCOR-Chronic diseases
of airways - Vagal receptors in the airway-Epithelial injury
and antigen (dog, cat, rabbit)
P50HL-19170-02 0003 Harvard pulmonary SCOR-Chronic
diseases of the airways - Mechanisms of bronchial
reactivity to acute and chronic airway challenge (dog)
ROlHL-19370-03 Coronary capillary exchange-The effects
of ischemia (dogs, sheep)
ROlHL-19455-03 Role of endothelial cells in vascular
permeability (tissue culture)
POlHL-19717-02 0037 Response of the lung to injury ■
Catecholamines, prostaglandins and nucleotides in
pulmonary function (animals)
ROlHL-19830-02 Shear to aortic histamine synthesis and
permeability (dogs)
ROlHL-20460-03 Aortic histamine synthesis in diabetes
(rat)
(coiM)
Heart preservation and transplantation
Circulation studies by one vs two circuit
IMI
POIHI 20581 01 0001 V«scul»i neuto«ttecloi
mechinisros in health and disease Vascular neuioetleclor
mechanism (rabbits)
ROIHI 20783 02 Airv»ay reactivity Badrenoceplors and
pn>sta(landins (guinea pigs)
ROIHI 2079302 Phospholipids and cardiac receptor
function
POIHL 2098402 000b Cellular mechanisms in cardiac
hypertrophy Neurohumoral receptors in cardiac growth
and compensatory hypertrophy (animals)
ROIHI 2098901 Pathophysiology ol bronchial asthma
(sheep, dogs)
R23HL21116 02 Mechanisms ot membrane and tissue
damage in lung (dogs, rabbits)
ROlHL-21314 02 Respiratory tract secretion ol ions, water
and mucus (human, dogs)
R23HL 2153902 Mechanical properties ol isolated small
bronchioles (rabbits)
POlHL-2158402 0005 Respiratory mechanics in normal
and abnormal states Regulation and behavior ot airvray
smooth muscle (human, animals)
•* ROlHL-22136-02 Histamine and cardiac adenyl cyclase
ROIHL 2217702 Mechanisms of control of pulmonary
smooth muscle (dogs)
ROlHL-2222301 The cardiopulmonary junction (dogs,
models)
ROlHL-2243502 Pulmonary alveolar-capillary permeability
characteristic (dogs)
ROlHL-2256101 Hormonal control of mesenteric
circulation (cats)
ROlHL-2256902 Intestinal secretion -Capillary and tissue
forces (dogs, cats)
POlHL-22602-01 0001 Pathophysiology of the
endothelium ■ Platelet-endothelial interactions in vitro
(human, cattle)
POlHL-22619-01 0008 Cellular mechanisms of heart
failure - Molecular mechanisms and differential contractile
responsiveness in VSM (dogs)
ROlHL-22924-01 The airway mucosal barrier (guinea pigs)
IMIDAZOLES, HISTAMINE LIBERATION
ROlHL-02953-17 Autonomic and cardiovascular
pharmacology (rats, rabbits, dogs, guinea pigs)
P01HL06285-18 0186 Cardiovascular-respiratory
physiology and biochemistry ■ Leukocyte hormone receptors
and cyclic nucleotides (tissue culture)
P50HL-1415307 0012 Johns Hopkins Lung Center-
Chronic diseases of airways - Aspirin intolerance in
reversible lung disease (human)
•* P50HL14153-07 0014 Johns Hopkins Lung Center-
Chronic diseases of airways - Mediator release in asthma
(human)
P50HL14153-07 0015 Johns Hopkins Lung Center-
Chronic diseases of airvrays - Kinins and human lung
P50HL1 5092-07 0005 Immune and tibrotic response to
occupational environments - Respiratory and immunologic
evaluation of toluene diisocyanate exposure (human)
ROlHL-17873-04 Pathophysiology of exercise-induced
asthma (human)
ROlHL-18526-03 Kinins and the human lung
ROlHL-19062-03 Pharmacologic control of mast cell
phosphodiesterase (human, rats)
** P50HL-19156-02 0004 Pulmonary SCOR-Chronic diseases
of airways - Interactions between mast cells, mediators
and nerves in canine asthma
ROlHL-22555-01 Structure and function of platelet
activating factor (rabbits, human)
*• ROlHL-23586-06 Pharmacologic control of hypersensitivity
phenomena (human)
** ROlHL-23593-01 Mast cell granules-Structure and
secretion (rats)
IMIDAZOLES, LEVAMISOLE
P60HL-16008-06 0019 Wayne State University
comprehensive sickle cell center - Cell mediated immunity
in sickle cell anemia (human)
ROlHL-2 1120-02 Membrane dynamics in alveolar
macrophages (rabbits)
IMIDAZOLES, PHENTOLAMINE
POlHL-06308-18 0011 Mechanisms and therapy of
circulatory disease - Blood flow and electrical dysfunction
in ventricular arrhythmia (human)
ROlHL-08359-14 Morphopharmacology of vascular
adrenergic transmission (rabbits, rats)
POlHL-12738-10 0108 Physiologic pharmacology and its
clinical applications - Developmental electrophysiology and
pharmacology (human, animals)
POlHL-1273810 0134 Physiologic pharmacology and its
clinical applications - Adenylate cyclase and cAMP
phosphodiesterase in cardiac development (dogs)
POlHL-14388-07 0151 Regulation of the circulation in
pathological states - Catecholamine release in potassium
ion-free contractures in the caudal artery
POlHL-17382-05 0002 Chemical mediators of acute
pulmonary disorders - Chemical mediators and respiratory
mechanics in guinea pigs
ROlHL-22306-01 Renal catecholamines- Pathophysiology
of hypertension (dogs)
ROlHL-22354-01 Alpha-adrenergic effects on heart
metabolism (rats)
ROlHL-22641-01 Ventilation, perfusion, and systemic
arterial reflexes (dogs)
295
IMIDAZOLES, TOLAZOUNE
ROIHL 20087 02 Developmental processes in pulmonary
hypertension (rats)
R23HL 22309 01 Cardiovascular pharmacodynamics in
immature dogs
7-IMIDAZO(4,5D)PYRIMIDINE
SEE PURINES
8,9C-IMINOETHANOPHENANTHRO(4.
5BCD)FURANS
SEE ALKALOIDS. MORPHINES
IMINOUREA
SEE GUANIDINES
IMIPRAMINE
SEE AZEPINES, IMIPRAMINE
IMMATURE ANIMAL FORMS
SEE AGE (ANIMAL), IMMATURE
IMMEDIATE HYPERSENSITIVITY
SEE HYPERSENSITIVITY, IMMEDIATE HYPERSENSITIVITY
IMMOBILIZATION OF ENZYMES
SEE ENZYME IMMOBILIZATION
IMMUNE ADHERENCE
SEE IMMUNOLOGY. IMMUNE ADHERENCE
IMMUNE ADHERENCE REACTION
SEE IMMUNOLOGICAL TESTS AND IMMUNOASSAY, IMMUNE
ADHERENCE REACTION
IMMUNE COMPLEX AUTOIMMUNE DISEASES
SEE IMMUNOPATHOLOGY, AUTOIMMUNE DISORDERS
IMMUNE COMPLEX DISEASES
SEE IMMUNOPATHOLOGY. IMMUNE COMPLEX DISEASES (SEE
ALSO SPECIFICS)
IMMUNE COMPLEXES
SEE IMMUNOLOGY. ANTIGEN-ANTIBODY REACTIONS. IMMUNE
COMPLEXES
IMMUNE DISORDERS
SEE IMMUNOPATHOLOGY (GENERAL)
IMMUNE ELECTRON MICROSCOPY
SEE OPTICS. MICROSCOPY, IMMUNE ELECTRON*
IMMUNE INCLUSION DISEASES
SEE IMMUNOPATHOLOGY, IMMUNE COMPLEX DISEASES (SEE
ALSO SPECIFICS)
IMMUNE SERA
SEE IMMUNOLOGY, ANTIBODIES, IMMUNE SERA
lAAMUNE TOLERANCE
SEE IMMUNITY, IMMUNOLOGICAL UNRESPONSIVENESS
IMMUNITY (AND NATURAL RESISTANCE)
(GENERAL)
SEE ALSO IMMUNOLOGY, ANTIBODIES, IMMUNE SERA
SEE ALSO IMMUNOLOGY, ANTIBODY FORMATION
SEE ALSO IMMUNOLOGY, ANTIGEN-ANTIBODY REACTIONS
ROlHL-16246-06 Immunologic studies in
postpericardiotomy syndrome (human)
** ROlHL-18997-02 Ischemic therapy in experimental
hypersplenism (rats, dogs)
** R01HL-20086-02 Circulatory control of splenic function
(rats)
** ROlHL-20675-02 Alveolar macrophage function in man
ROlHL-22582-01 Pulmonary and circulatory alterations
induced by IGE
IMMUNITY, AUTOIMMUNITY
SEE IMMUNOPATHOLOGY, AUTOIMMUNE DISORDERS
IMMUNITY, BACTERICIDAL DEFENSES (GENERAL)
SEE ALSO IMMUNOLOGY, ACUTE PHASE PROTEINS
SEE ALSO IMMUNOLOGY, ANTIBODIES, OPSONINS
SEE ALSO IMMUNOLOGY, ANTIBODIES BACTERIAL
SEE ALSO IMMUNOLOGY, ANTITOXINS
SEE ALSO IMMUNOLOGY, PROPERDIN
SEE ALSO VACCINES, BACTERIAL (GENERAL)
** R01HL-01803-23 0018 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Fetal immunization in pathogenesis of
glomerulonephritis in adult (rabbit)
ROlHL-01803-23 0019 Arteriosclerosis, glomerulonephritis,
rheumatic fever ■ Pathogenesis of rheumatic heart disease
(rabbit)
M POlHL-06314-17 Immunologic mechanisms in
cardiovascular disease
** POlHL-06314-17 0046 Immunologic mechanisms in
cardiovascular disease ■ Mediators of immune injury
(human, mice)
POlHL-06314-17 0047 Immunologic mechanisms in
cardiovascular disease - Role of intravascular coagulation
(human, animals)
POlHL-063 14-17 0060 Immunologic mechanisms in
cardiovascular disease ■ Strept antigens and infections in
cardiovascular complications (human, animals)
** POlHL-08682-15 0019 Regulation of the cardiovascular
system - Hepatic immunophysiology and host-defense in
shock (rat, dog, human)
IMM
ROIHI 13824 06 Defense mechannmi in pathogenttii ol
emphysema (human, dogs)
• ROIHI 1388508 0006 Cystic fibrosis and pulmonary
disease Cell mediated immunity and Pseudomonai
infections in cystic fibrosis (human)
• ROIHI 13885 08 0007 Cystic fibrosis and pulmonary
disease Alveolar macrophage defense mechanism
(human, rabbits)
ROIHL 1388508 0008 Cystic fibrosis and pulmonary
disease Pseudomonas specific activation of alveolar
macrophages (human, rabbits)
• P50HL 14212 07 0006 Correlated studies of pulmonary
fibrosis Alveolar macrophage physiology (human, rodents,
rabbits)
• P50HL 14212 07 0015 Correlated studies ol pulmonary
fibrosis Pulmonary defense mechanisms and librotic lung
disease (rodents, rabbits)
'* P50HL1421807 0005 Pulmonary SCOR Newborn lung
center Prevention ol inlection in inlants with respiratory
distress (human)
■• P50HL15061 07 0007 Response of lung to in)ury
Human factors for phagocytosis in normal and diseased
lungs
•* P50HL- 15061 07 0009 Response of lung to injury •
Alveolar macrophages (human, rabbits)
P60HL-15160-07 0014 Center lor sickle cell disease -
Replacement therapy of opsonin deficiency in sickle cell
anemia (children)
" P60HL 15169-05 0009 Support for center for sickle cell
disease - Infections in sickle cell anemia (human)
POlHL-15832-06 0009 Chemical structural predispositions
to lung injury Immunology- Enzyme degradation products
of human lung elastin and microlibril
** P60HL 15999-05 0008 Miami comprehensive sickle cell
center Cyanate elfect on host defense -Cellular and
humoral (human, guinea pig, rabbits)
** P60HL-15999-05 0020 Miami comprehensive sickle cell
center - Deficiency in complement-dependent humoral
immunity-Sickle cell disease (human)
*• P60HL- 1600505 0020 Comprehensive sickle cell center -
Studies of the immunologic delect in sickle cell anemia
(human)
P60HL-16008-06 0019 Wayne State University
comprehensive sickle cell center - Cell mediated immunity
in sickle cell anemia (human)
POlHL-16748-05 0004 Cellular and immunological basis
ol pulmonaiv diseases ■ Cellular and immunological
processes in pulmonary delense systems
** POlHL-16769-05 0008 Pathobiologic and host defense
reactions in the lung ■ Pulmonary immunocylologic defense
mechanisms against bacteria (human, animals)
P60HL- 17265-04 0009 Community blood resource center
support - Research -Developing granulocyte transfusion
therapy (human, rabbit)
P50HL19157-02 0003 Studies in cystic fibrosis and
bronchiolitis - Nasal mucosal function in patients with
cystic fibrosis
P50HL-19157-02 0008 Studies in cystic librosis and
bronchiolitis - Serum proteins in cystic fibrosis (human)
P50HL-19171-02 0001 Pulmonary SCOR -Lung injury by
childhood inlections - Longitudinal study-Respiratory
inlections and lung growth in normal children
P50HL-19171-02 0003 Pulmonary SCOR-Lung injury by
childhood inlections - Natural history, host defense defects-
Children with chronic pulmonary disease
" P50HL-19171-02 0007 Pulmonary SCOR-Lung injury by
childhood infections - Immunologic studies in models ot
lower respiratory tract inlection (rodents)
P50HL-19171-02 0009 Pulmonary SCOR-Lung injury by
childhood inlections - Host-parasite interaction -Scanning
electron microscopy, freeze-fracture methods
P50HL-19171-02 0012 Pulmonary SCOR-Lung injury by
childhood infections - Laboratory support core
R23HL-19584-01 Alveolar macrophage responses to toxic
particle exposure (guinea pigs, human)
ROlHL-19628-03 Mechanisms ot pulmonary alveolar
proteinoses (human, rats)
ROlHL-19741-03 Murine CRD -A model ol chronic
pulmonary inllammation (mice, rats)
** R01HL-19774-03 Pathogenesis of chronic lung disease
(rats, mice, bacteria)
ROlHL-19818-02 Endocarditis on prosthetic heart valves
(rabbits, human)
R01HL-20002-03 Pulmonary complications of viral
infections (children)
** ROlHL-20063-03 Pathogenesis of pulmonary mycoplasma
inlections (guinea pigs, mice)
ROlHL-20086-02 Circulatory control ol splenic lunction
(rats)
•* ROlHL-20314-02 Host delense against S pheumoniae in
sickle cell disease (human)
** ROlHL-20352-02 Delenses of lung cells against oxygen
toxicity (human, animals)
ROlHL-20675-02 Alveolar macrophage lunction in man
P60HL-20985-01 0002 Northern Calilornia sickle cell
center - Immunization with polyvalent pneumococcal
polysaccharide vaccine (human)
R23HL-21997-01 Pulmonary immunopathology in the
compromised host (guinea pigs)
ROlHL-22029-02 Bronchopulmonary resistance to bacterial
inlection (mice)
(contd)
•Excludes routine nethodotogy OR covers only general pro)ects which preclude
"Oriented signiticanthr to above subject
indexing at the specific level.
VI Grant has suhprojects descnbing specific research aspects.
See Appendix for Investigator's name and grant number
IMM
R23HL-22895-01 Smoke inhalation-Biochemical and
cellular responses (rabbits, bacteria)
P60HL-23282-01 0002 Comprehensive hospital/community
sickle cell center - Clinical evaluation of alternate
pathaviay of compliment activation
IMMUNITY, CELLULAR IMMUNITY (GENERAL)
SEE ALSO BLOOD CELL DEPLETION THERAPY, T LYMPHOCYTE
DEPLETION
SEE ALSO BLOOD CELLS, T LYMPHOCYTES
SEE ALSO HYPERSENSITIVITY, DELAYED HYPERSENSITIVITY
SEE ALSO HYPERSENSITIVITY, LYMPHOKINES
SEE ALSO IMMUNOLOGY. IMMUNOREGUUTORY ALPHA
GLOBULIN
SEE ALSO IMMUNOPATHOLOGY. AUTOIMMUNE DISORDERS
SEE ALSO TISSUE COMPATIBILITY-TRANSPLANT,
ISOALLOIMMUNin
ROlHL-01623-24 Antigens related to graft rejection
(rabbits, rats)
ROlHL-01661-27 Hemostatic mechanisms (human)
ROlHL-01803-23 0001 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Post-streptococcal glomerulonephritis
(rabbit)
ROlHL-03180-21 Relation of lymphatics to
cardiopulmonary function (dogs)
R01HL-03919-20 The cell suface of streptococci (rats,
human)
P01HLG6285-18 0186 Cardiovascular-respiratory
physiology and biochemistry - Leukocyte hormone receptors
and cyclic nucleotides (tissue culture)
POlHL-06314-17 0050 Immunologic mechanisms in
cardiovascular disease - Physiologic changes in
lymphocytes (human, mice)
POlHL-06314-17 0059 Immunologic mechanisms In
cardiovascular disease - Immunogenetic response to
streptococcal antigens In man
POlHL-06314-17 0061 Immunologic mechanisms in
cardiovascular disease - Role of viruses In cardiovascular
and renal disease (human, mice)
POlHL-0631417 0064 Immunologic mechanisms in
cardiovascular disease - Diabetic vascular disease (human.
rats, mice)
P01HL-D6314-17 0066
cardiovascular disease -
Immunologic mechanisms in
Sensitization, cell-mediated
cytotoxicity, role of lymphocytes (human, mice)
P01HL0631417 0067 Immunologic mechanisms in
cardiovascular disease - Mitogenic and antigenic activation
of lymphocyte sub-populations
POlHL-06370-17 0001 Cardiopulmonary and renal
pathology research center - The humoral and cellular
mechanisms of allograft rejection (monkeys)
ROlHL-08696-15 0004 Orthotopic heart transplantation ■
Transplantation immunology-Avian antibody studies
(chickens, rats, rabbits)
ROlHL-08696-15 0010 Orthotopic heart transplantation ■
Transplantation immunology-Total lymphoid irradiation
(dogs, primates)
POlHL-09011-15 0013 A research and resource program
in blood - A quantitative study of immunological
enhancement (mice)
POlHL-13108-09 0011 Clinical heart transplantation -
Humoral and cellular kinetics of allograft rejection (human)
P01HL13108-09 0013 Clinical heart transplantation -
Cardiomyopathic lymphocyte responsiveness to cultured
endothelium
ROlHL-13885-08 0006 Cystic fibrosis and pulmonary
disease - Cell mediated immunity and Pseudomonas
infections In cystic fibrosis (human)
ROlHL-13987-04 Transplantation of the lung (dogs)
P50HL-14136-07 0003 Pulmonary SCOR-Airways
obstructive diseases - Acute pediatric respiratory disease
and COLD
Pulmonary SCOR-Airways
Pediatric airways obstructive disease
P50HL-14136-07 0017
obstructive diseases
(human)
P50HL14212-07 0013
Correlated studies of pulmonary
fibrosis - Mechanism of beryllium pathogenicity in the lung
(human, rabbit, guinea pig)
P50HL-14212-07 0015 Correlated studies of pulmonary
fibrosis - Pulmonary defense mechanisms and fibrotic lung
disease (rodents, rabbits)
ROlHL-14262-07 Leukocyte proteases and their lung
targets (human, dogs, rabbits)
ROlHL-14799-07 Cardiac heterotransplantation-
Immunologic modification (mice, rat)
P50HL15061-07 0010 Response of lung to Injury - An
animal model system for the study of bronchiolitis and its
sequellae (dogs)
P50HL-15092-07 Immune and fibrotic response to
occupational environments
** P50HL-I5092-07 0006 Immune and fibrotic response to
occupational environments - Immunologic studies In
silicosis (human, rabbits, hamsters, guinea pigs)
'* P50HL-15092-07 0007 Immune and fibrotic response to
occupational environments ■ Asbestosis -Cellular Immunity,
structure and mineral localization (human)
P50HL-1509207 0008 Immune and fibrotic response to
occupational environments - Animal models of asbestosis
(hamsters)
ROlHL-15124-05 Genesis of hypertension in renal disease
(human, dogs)
M
296
P50HL1538907 0011 Pulmonary SCOR -Hypersensitivity
pneumonitis - Animal model-Hypersensitivity pneumonitis
in rabbits
P50HL-15389-07 0013 Pulmonary SCOR -Hypersensitivity
pneumonitis ■ Animal model-Pulmonary mycotoxicosis
(rabbit, guinea pig)
P60HL-15999-05 0008 Miami comprehensive sickle cell
center - Cyanate effect on host defense -Cellular and
humoral (human, guinea pig, rabbits)
* P60HL16008-06 0019 Wayne State University
comprehensive sickle cell center - Cell mediated immunity
in sickle cell anemia (human)
ROlHL-167 11-05 RBC and endothelial membrane material
characteristics (human)
POIHL 16748-05 Cellular and immunological basis of
pulmonary diseases
POlHL-16748-05 0001 Cellular and immunological basis
of pulmonary diseases - Mechanisms of alveolar
macrophage function and dysfunction (human, rabbits)
' POIHL 16748-05 0004 Cellular and Immunological basis
of pulmonary diseases - Cellular and immunological
processes in pulmonary defense systems
' POIHL 16748-05 0006 Cellular and immunological basis
of pulmonary diseases - Sarcoidosis-Studies with bronchial
lavage (human)
' ROlHL-16757-04 'Autoimmune' thrombocytopenia (monkey)
POlHL-16769-05 0008 Pathobiologic and host defense
reactions in the lung - Pulmonary immunocytologic defense
mechanisms against bacteria (human, animals)
POlHL-16769-05 0010 Pathobiologic and host defense
reactions in the lung - Bronchus associated lymphoid
tissue and delayed hypersensitivity (rabbits)
P60HL-1 7269-04 0033 National heart and blood vessel
research and demonstration center - Autoallergic response
in cardiomyopathy, atherosclerosis, rheumatic heart disease
P60HL-1726904 0035 National heart and blood vessel
research and demonstration center - Blood resources-
Research program in viral hepatitis (human)
POlHL-18646-03 0001 Studies basic to heart
transplantation - Individualized regulation of
immunosuppression (dogs, rats)
POlHL-18646-03 0002 Studies basic to heart
transplantation - Detection of rejection (dogs)
POlHL-18646-03 0003 Studies basic to heart
transplantation - Host responses to xenografts (rodents.
rabbits)
POlHL-18646-03 0004 Studies basic to heart
transplantation - Presensitization-Detection, Incidence and
clinical significance
POlHL-18646-03 0006 Studies basic to heart
transplantation - Reduction or elimination of existing
presensitization (human, animals)
' POlHL-18827-02 0006 Platelet vessel wall interactions in
thrombogenesis - Platelet Immune injury in man
ROlHL-18936-02 Heart preservation and transplantation
studies (rat)
ROlHL-190 18-03 Etiologic factors in cryptogenic fibrosing
alveolitis (human)
P50HL-191 71-02 0007 Pulmonary SCOR-Lung injury by
childhood Infections - Immunologic studies in models of
lower respiratory tract infection (rodents)
ROlHL-1923403 Streptococci and heart-Cell-mediated
cross-reaction (mice)
ROlHL-19429-03 Phagocytosis-lngestion in alveiolar
macrophages (rabbits)
ROlHL-19628-03 Mechanisms of pulmonary alveolar
proteinoses (human, rats)
ROlHL-19651-03 Host factors in pathogenesis of
respiratory disease (human, hamsters)
ROlHL-19711-03 Lymphokines in pulmonary granulomas
(guinea pigs)
POlHL-197 17-02 Response of the lung to injury
POlHL-19717-02 0016 Response of the lung to injury -
The alveolar macrophage in elastase emphysema (guinea
pigs, hamsters)
POlHL-19717-02 0019 Response of the lung to injury -
Animal model of fibrosing alveolitis (hamsters, guinea
pigs, rabbits)
POlHL-19717-02 0041 Response of the lung to injury -
Cellular immunity In interstitial lung disease (human)
ROlHL-19741-03 Murine CRD-A model of chronic
pulmonary inflammation (mice, rats)
ROlHL-19760-01 Cellular immune responses of the lung
(mice, guinea pigs)
ROlHL-19774-03 Pathogenesis of chronic lung disease
(rats, mice, bacteria)
ROlHL-198 19-03 Mitogen induced interstitial pneumonitis
(rabbits)
ROlHL-19873-03 Pulmonary responses to inhaled antigen
(rabbits, guinea pigs)
ROlHL-20063-03 Pathogenesis of pulmonary mycoplasma
infections (guinea pigs, mice)
ROlHL-201 25-02 Cyclic nucleotides and alveolar
macrophage activation (rabbits)
ROlHL-20301-02
human blood
ROlHL-20533-09
Genetics of glycosyltransferases In
Pathogenesis of rheumatic fever (human.
rabbits)
ROlHL-21047-01 Studies of coxsackievirus-induced
myocarditis in mice
R23HL-212 12-02 Alveolar macrophage function in
Pseudomonas Infection (dgs)
Bronchopulmonary resistance to bacterial
'Excludes routine methodology OR covers only general projects which preclude indexing
•"Oriented significantly to above subject
at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
IMM
** ROlHL-21829-01 Etiology of obstructive airway disease in
children (also monkeys)
R23HL-21918-01 Hypersensitivity pneumonitis in guinea
pigs
ROlHL-22029-02
infection (mice)
ROlHL-22257-01 Leukoklnesis enhancing factor and lung
infections (human, rats)
ROlHL-22301-01 Immunogenetics of chronic pulmonary
inflammation (mice)
** ROlHL-22302-01 Immune responses in the human lung
(also rabbits, monkeys)
** ROlHL-22456-01 Lipoproteins in bioregulation of the
immune response (mice, human)
** ROlHL-22676-01 Pathogenesis in experimental interstitial
pneu.Tionitis (rabbits)
" R23HL-22823-01 Phagocytic and Immune defense
mechanisms of the lung (mice)
ROlHL-23586-06 Pharmacologic control of hypersensitivity
phenomena (human)
IMMUNITY, CEUULAR, LYMPHOCYTE
ACTIVATION, TRANSFORMATION AND
PROLIFERATION
SEE ALSO HYPERSENSITIVITY, LYMPHOKINES, LYMPHOCYTE
TRANSFORMING FACTORS
** POlHL-06314-17 0053 Immunologic mechanisms in
cardiovascular disease - Cellular functions controlled by
cyclic GMP (human, mice, guinea pigs)
P50HL- 15092-07 0005 Immune and fibrotic response to
occupational environments - Respiratory and immunologic
evaluation of toluene diisocyanate exposure (human)
P50HL-15092-07 0007 Immune and fibrotic response to
occupational environments • Asbestosis -Cellular immunity,
structure and mineral localization (human)
ROlHL-15124-05 Genesis of hypertension in renal disease
(human, dogs)
P50HL-15389-07 0001 Pulmonary SCOR-Hypersensitivity
pneumonitis - Clinical studies of hypersensitivity
pneumonitis
P60HL-16008-06 0019 Wfayne State University
comprehensive sickle cell center - Cell mediated immunity
in sickle cell anemia (human)
" POIHL- 174 17-05 0001 Experimental lung transplantation
- Mechanisms and mediators of lung allograft rejection
(dogs, mice)
POlHL-17417-05 0003 Experimental lung transplantation
- Methods for detecting lung allograft rejection (dogs)
** R01HL19132-04 Role of zinc transferrin In lymphocyte
transformation (human)
ROlHL-19628-03 Mechanisms of pulmonary alveolar
proteinoses (human, rats)
ROlHL-19760-01 Cellular immune responses of the lung
(mice, guinea pigs)
ROlHL-20971-10 Membrane glycoproteins of platelets and
leukocytes (human)
R23HL-21212-02 Alveolar macrophage function In
Pseudomonas infection (dgs)
R23HL-21918-01 Hypersensitivity pneumonitis in guinea
pigs
ROlHL-22257-01 Leukoklnesis enhancing factor and lung
infections (human, rats)
ROlHL-22456-01 Lipoproteins in bioregulation of the
immune response (mice, human)
IMMUNITY, CROSS IMMUNITY
SEE ALSO MICROBIAL IDENTIFICATION AND CLASSIFICATION,
SEROTYPING
R01HL03919-20 The cell suface of streptococci (rats.
human)
P50HL-17665-04 0011 Study of ischemic heart disease -
Development of new methods for the determination of
infarct size (dog. human)
P50HL-1 7665-04 0032 Study of ischemic heart disease -
Myocardial infarct sizing-lmmunoassay for cardiac myosin
light chains (dogs)
ROlHL-20533-09 Pathogenesis of rheumatic fever (human,
rabbits)
IJMMUNITY, HUMORAL IMMUNITY
SEE ALSO BLOOD CELLS, B LYMPHOCYTES
ROlHL-01623-24 Antigens related to graft rejection
(rabbits, rats)
ROlHL-01803-23 0018 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Fetal Immunization In pathogenesis of
glomerulonephritis in adult (rabbit)
ROlHL-01803-23 0019 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Pathogenesis of rheumatic heart disease
(rabbit)
ROlHL-03180-21 Relation of lymphatics to
cardiopulmonary function (dogs)
POlHL-06285-18 0186 Cardiovascular-respiratory
physiology and biochemistry ■ Leukocyte hormone receptors
and cyclic nucleotides (tissue culture)
POlHL-06314-17 0060 Immunologic mechanisms in
cardiovascular disease - Strept antigens and infections In
cardiovascular complications (human, animals)
POlHL-06314-17 0061 Immunologic mechanisms in
cardiovascular disease - Role of viruses In cardiovascular
and renal disease (human, mice)
POlHL-06314-17 0064 Immunologic mechanisms in
cardiovascular disease - Diabetic vascular disease (human,
rats, mice)
(contd)
IMM
P01HL063MW 0067 Immunologic mechjnisms m
c«rtlow»scul»f di$««s« Mltojonic ind jntigenic activation
ol lymphocyte sub-populations
' PO1HLO6370 U 0001 Cardiopulmonary and lanal
pathology lesaaich caiitei The humoial and cellular
mechanisms ol allogiatt rejection (monkeys)
ROIHL 08696 lb 0010 Orthotopic heart transplantation
Transplantation immunology-Total lymphoid irradiation
(dogs, primates)
POIHL 09011 lb 0013 A research and resource program
in blood A quantitative study ol immunological
enhancement (mice)
• POIHL 13108 09 0011 Clinical heart transplantation
Humoral and cellular kinetics ol allograft reiection (human)
ROIHL 13987 04 Transplantation of the lung (dogs)
PbOHL 1413607 0003 Pulmonary SCOR Airways
obstructive diseases Acute pediatric respiratory disease
and COLD
P50HL 1413507 0017 Pulmonary SCOR Airways
obstructive diseases Pediatric airways obstructive disease
(human)
P50HL 14212-07 001b Correlated studies ol pulmonary
fibrosis Pulmonary defense mechanisms and fibrotic lung
disease (rodents, rabbits)
POIHL 1438807 0185 Regulation of the circulation in
pathological states Reflex control of venous tone (human,
rabbits, dogs)
"• POIHL 14388-07 0198 Regulation of the circulation in
pathological states Humoral factors in vascular reactivity
in spontaneously hypertensive rats
ROIHL 14700-05 Humoral and lung protease-anliprotease
role in obstructive disease (human)
ROlHL-14799-07 Cardiac heterotransplantation -
Immunologic modification (mice, rat)
P50HL-15061-07 0010 Response of lung to injury - An
animal model system for the study of bronchiolitis and its
sequellae (dogs)
P50HL-15389-07 0001 Pulmonary SCOR -Hypersensitivity
pneumonitis ■ Clinical studies of hypersensitivity
pneumonitis
P50HL-15389-07 0008 Pulmonary SCOR -Hypersensitivity
pneumonitis Milwaukee patient study -Hypersensitivity
pneumonitis
P50HL-lb389-07 0011 Pulmonary SCOR-Hypersensitivity
pneumonitis - Animal model-Hypersensitivity pneumonitis
in rabbits
P50HL- 15389-07 0013 Pulmonary SCOR-Hypersensitivity
pneumonitis - Animal model -Pulmonary mycotoxicosis
(rabbit, guinea pig)
POlHL-15832-06 0009 Chemical-structural predispositions
to lung injury - Immunology-Enzyme degradation products
of human lung elastin and microfibril
P60HL-1599905 0008 Miami comprehensive sickle cell
center - Cyanatc effect on host defense -Cellular and
humoral (human, guinea pig, rabbits)
P60HL-15999-05 0020 Miami comprehensive sickle cell
center - Deficiency in complement-dependent humoral
immunity -Sickle cell disease (human)
M POlHL-16748-05 Cellular and immunological basis of
pulmonary diseases
** POlHL-16748-05 0002 Cellular and immunological basis
of pulmonary diseases - Immunological function of alveolar
macrophages (rabbits, sheep, mice)
** ROlHL-16757-04 Autoimmune' thrombocytopenia (monkey)
POlHL-16769-05 0008 Pathobiologic and host defense
reactions in the lung - Pulmonary immunocytologic defense
mechanisms against bacteria (human, animals)
P60HL-1 7269-04 0033 National heart and blood vessel
research and demonstration center - Autoallergic response
in cardiomyopathy, atherosclerosis, rheumatic heart disease
POlHL-18646-03 0003 Studies basic to heart
transplantation - Host responses to xenografts (rodents,
rabbits)
POlHL-18646-03 0004 Studies basic to heart
transplantation - Presensitization-Detection. incidence and
clinical significance
POlHL-18646-03 0006 Studies basic to heart
transplantation - Reduction or elimination of existing
presensitization (human, animals)
** ROlHL-18731-02 RES stimulating materials in
experimental shock (dogs)
** POlHL-18827-02 0006 Platelet vessel viall interactions in
thrombogenesis - Platelet immune injury in man
ROlHL-18936-02 Heart preservation and transplantation
studies (rat)
P50HL-19153-02 0002 SCOR -Pulmonary edemas -Eitology,
pathogenesis Lung fluid dynamics-Classical mediators
and their inhibitors (sheep)
P50HL-19153-02 0003 SCOR-Pulmonary edemas-Eitology.
pathogenesis - Possible inhibitors of mediator release and
pulmonary vascular response (sheep)
P50HL-19171-02 0007 Pulmonary SCOR-Lung injury by
childhood infections - Immunologic studies in models of
lower respiratory tract infection (rodents)
ROlHL-19234-03 Streptococci and heart -Cell-mediated
cross-reaction (mice)
ROlHL-19628-03 Mechanisms of pulmonary alveolar
proteinoses (human, rats)
ROlHL-19651-03 Host factors in pathogenesis of
respiratory disease (human, hamsters)
ROlHL-19873-03 Pulmonary responses to inhaled antigen
(rabbits, guinea pigs)
297
R23HI 2191801 Hypersensitivity pneumonitis in guinea
pigi
ROIHL 22029 02 Bronchopulmonary resistance to bacterial
intection (mice)
ROIHL 22087 02 Humoral mediators ol pulmonary
inflammation (guinea pigs)
ROIHL 22456 01 Lipoproteins in bioregulation ol the
immune response (mice, human)
R23HL 22823 01 Phagocytic and immune defense
mechanisms of the lung (mice)
ROIHL 23654 01 Selected topics on blood transfusion
(rabbits, human)
IMMUNITY, IMMUNIZATION (IMMUNOTHERAPY)
SEE ALSO IMMUNOLOGICAL PREPARATIONS
(GENERALKINCLUDING CERTIFICATION AND
STANDARDIZATION)
NOlHB-6290807 Maternal to infant transmission of
hepatitis B (human)
** ROlHL-01803 23 0001 Arteriosclerosis, glomerulonephritis,
rheumatic fever Post streptococcal glomerulonephritis
(rabbit)
ROIHL 01803 23 0011 Arteriosclerosis, glomerulonephritis,
rheumatic fever Immunopathologic consequences of
cigarette smoking (human, rabbits, plants)
ROlHL-05975-18 Pathogenesis and prevention of
hypertension (rats)
POIHL 1034213 0028 The integrated function of
respiration and circulation Mediator release,
hemodynamics and respiratory function in anaphylaxis
(dogs)
P60HL-16008-06 0019 Wayne State University
comprehensive sickle cell center Cell mediated immunity
in sickle cell anemia (human)
ROlHL-16119-05 Spleen and marrow allografts in
hereditary anemia (mice)
** ROlHL-16757-04 'Autoimmune' thrombocytopenia (monkey)
POlHL-16769-05 0008 Pathobiologic and host defense
reactions in the lung - Pulmonary immunocytologic defense
mechanisms against bacteria (human, animals)
** P60HL-17269-04 0034 National heart and blood vessel
research and demonstration center - Immunologic
enhancement of cardiac allografts (mice)
M POlHL-19259-03 Digoxin-specific antibody in human
therapy
POlHL-19259-03 0001 Digoxin-specific antibody in human
therapy - Primary structure of monoclonal antibodies
(rabbits)
POIHL- 192 59-03 0002 Digoxin-specific antibody in human
therapy - Chemical semi-synthesis of digoxin-specific
antibody (rabbits)
POlHL-19259-03 0003 Digoxin-specific antibody in human
therapy - Synthesis of dogoxin-specific antibody in
continuous cell culture (human, sheep)
POIHL 19259-03 0004 Digoxin-specific antibody in human
therapy - Digitalis-specific antibodies pharmacological
studies (human, dogs, sheep)
ROlHL-19628-03 Mechanisms of pulmonary alveolar
proteinoses (human, rats)
ROlHL-197 11-03 Lymphokines in pulmonary granulomas
(guinea pigs)
R01HL-19733-03 Absorption of antigen through inflamed
lungs (rabbits)
ROlHL-19760-01 Cellular immune responses of the lung
(mice, guinea pigs)
ROlHL-197 74-03 Pathogenesis of chronic lung disease
(rats, mice, bacte'ia)
ROlHL-198 18-02 Endocarditis on prosthetic heart valves
(rabbits, human)
R01HL-20063-03 Pathogenesis of pulmonary mycoplasma
infections (guinea pigs, mice)
ROlHL-20104-03 Pulmonary granulomatous inflammations
(mice)
ROlHL-20856-02 Platelet transfusions-Usage and
complications (human)
ROlHL-21565-02 Pathogenesis of inflammatory lung injury
(rats, rabbits)
IMMUNITY, IMMUNIZATION,
HYPERIMMUNIZATION
** ROlHL-01803-23 0019 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Pathogenesis of rheumatic heart disease
(rabbit)
lAAMUNITY, IMMUNIZATION ACTIVE
** P60HL-15162-07 0021 Comprehensive sickle cell center -
Pneumococcal vaccine in sickle cell disease (children)
P60HL-17269-04 0034 National heart and blood vessel
research and demonstration center - Immunologic
enhancement of cardiac allografts (mice)
ROlHL-17751-03 Experimental endocarditis (rabbits)
** P60HL-20985-01 0002 Northern California sickle cell
center - Immunization v»ith polyvalent pneumococcal
polysaccharide vaccine (human)
R23HL-21918-01 Hypersensitivity pneumonitis in guinea
pigs
IMMUNITY, IMMUNIZATION PASSIVE
SEE ALSO IMMUNOLOGY. ANTITOXINS
** POlHL-09011-15 0020 A research and resource program
in blood - Passive immunization in the prevention of
transmission of hepatitis 8 (human)
IMM
•• ROIHI 19551 01 Hoil factors in palhofenens ol
respiratory disease (human. ham»teri)
ROIHI 19/41 03 Murine CHD A model ol chronic
pulmonary inflammation (mice, rats)
R23HI 21918 01 Hypersensitivity pneumonitis in guinea
pigs
ROIHL 2202902 Bronchopulmonary resistance to bacterial
infection (mice)
IMMUNITY, IMMUNOLOGICAl
UNRESPONSIVENESS
SEE ALSO IMMUNITY, IMMUNOSUPPRESSION
SEE ALSO IMMUNOPAIHOLOGY. IMMUNOIOGIC DEFICIENCY
DISORDERS
SEE ALSO METABOLIC DISORDERS INBORN. ANGIONEUROTIC
EDEMA (HEREDITARY)
SEE ALSO METABOLIC DISORDERS INBORN. CHEDIAK HIGASHI
SYNDROME
POIHL 06314 17 0067 Immunologic mechanisms in
cardiovascular disease Mitogenic and antigenic activation
of lymphocyte sub-populations
ROIHL 1388508 0006 Cystic fibrosis and pulmonary
disease Cell mediated immunity and Pseudomonas
infections in cystic fibrosis (human)
P50HL-15092 07 0007 Immune and fibrotic response to
occupational environments Asbestosis -Cellular immunity,
structure and mineral localization (human)
POlHL-16769-Ob 0007 Pathobiologic and host defense
reactions in the lung Immunogenetic factors m
sarcoidosis (human)
ROIHL 20014 02 Radioimmunoassay of hyper and
hypocoagulable states (rabbits)
** R23HL-21997-01 Pulmonary immunopathology in the
compromised host (guinea pigs)
ROlHL-22301-01 Immu oogenetics of chronic pulmonary
inflammation (mice)
IMMUNITY, IMMUNOSUPPRESSION
SEE ALSO HYPERSENSITIVITY DESENS1TI2ATI0N
M POlHL-06312-17 Surgical cardiology
POlHL-06312-17 0017 Surgical cardiology Cardiac
transplantation (human)
" POlHL-06312-17 0021 Surgical cardiology - Cardiac
transplantation-Effect ol immunosuppression on
atherogenesis (monkeys)
POlHL-06312-17 0039 Surgical cardiology - Cardiac
transplantation-Biopsy correlates of rejection
** POlHL-06370-17 0013 Cardiopulmonary and renal
pathology research center - Morphologic analysis of
vascular prosthesis (human, dogs)
ROlHL-08696-15 0001 Orthotopic heart transplantation •
Transplantation immunology-Antithymocyte globulin
(rabbits, monkeys)
ROlHL-08696-15 0010 Orthotopic heart transplantation -
Transplantation immunology-Total lymphoid irradiation
(dogs, primates)
** ROlHL-08696-15 0011 Orthotopic heart transplantation ■
Transplantation immunology-lmmunodepressive factor
(human, dogs)
** ROlHL-08696-15 0012 Orthotopic heart transplantation -
Transplantation immunology-Modulation of donor
antigenicity (dogs)
** POlHL-13108-09 0010 Clinical heart transplantation -
Serum factors inhibiting lymphocyte responses in MLC
(human, bush babies)
** POlHL-13108-09 0011 Clinical heart transplantation -
Humoral and cellular kinetics of allograft rejection (human)
** POlHL-13 108-09 0016 Clinical heart transplantation ■
Total lymphoid irradiation for immune response (dogs)
P50HL-14212-07 0015 Correlated studies of pulmonary
fibrosis - Pulmonary defense mechanisms and fibrotic lung
disease (rodents, rabbits)
ROlHL-14799-07 Cardiac heterotransplantation-
Immunologic modification (mice, rat)
P60HL- 15999-05 0008 Miami comprehensive sickle cell
center - Cyanate effect on host defense -Cellular and
humoral (human, guinea pig, rabbits)
POlHL-16748-05 0002 Cellular and immunological basis
of pulmonary diseases - Immunological function of alveolar
macrophages (rabbits, sneep, mice)
ROlHL-16757-04 'Autoimmune' thrombocytopenia (monkey)
POlHL-16769-05 0007 Pathobiologic and host defense
reactions in the lung - Immunogenetic factors in
sarcoidosis (human)
POlHL-16769-05 0008 Pathobiologic and host defense
reactions in the lung - Pulmonary immunocytologic defense
mechanisms against bacteria (human, animals)
P60HL-17265-04 0006 Community blood resource center
support - Research-Evaluation of platelet transfusions
(human, dog)
POlHL-17417-05 0004 Experimental lung transplantation
- Methods for suppressing lung allograft rejection (dogs,
mice)
M POlHL-18646-03 Studies basic to heart transplantation
** POIHL- 18646-03 0001 Studies basic to heart
transplantation - Individualized regulation of
immunosuppression (dogs, rats)
POlHL-18646-03 0003 Studies basic to heart
transplantation - Host responses to xenografts (rodents,
rabbits)
POlHL-18646-03 0004 Studies basic to heart
transplantation - Presensitization-Detection. incidence and
clinical significance
(conld)
•Excludes routine methodology OR covers only general projects which preclude
••Onented significantly to above subject.
indexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
■MM
POlHL-18646-03 0006 Studies basic to heart
transplantation - Reduction or elimination of existing
presensitization (human, animals)
P01HL18646-03 0009 Studies basic to heart
transplantation ■ Pathologic aspects of cardiac allograft
rejection (sheep, dogs)
ROlHL-19628-03 Mechanisms of pulmonary alveolar
proteinoses (human, rats)
ROlHL-21047-01 Studies of coxsackievirus-induced
myocarditis in mice
IMMUNITY, IMMUNOSUPPRESSION,
AUOANTISERA
M ROlHL-08696-15 Orthotopic heart transplantation
POlHL-1 3 108-09 0001 Clinical heart transplantation •
Therapy and prognosis (human)
P01HL131 08-09 0002 Clinical heart transplantation -
Preoperative immunologic studies of cardiac recipients
** P01HL13108-09 0009 Clinical heart transplantation - B
cell alloantigens in cardiac allograft compatibility (human)
" P01HL1310809 0012 Clinical heart transplantation -
Human T cell sheep erythrocyte receptors
R01HL13987-04 Transplantation of the lung (dogs)
POlHL-18646-03 0004 Studies basic to heart
transplantation - Presensitization-Detection, incidence and
clinical significance
lAAMUNITY, IMMUNOSUPPRESSION,
AUOANTISERA, ANTILEUKOCYTIC
** R01HL08696-15 0001 Orthotopic heart transplantation -
Transplantation immunology -Antithymocyte globulin
(rabbits, monkeys)
** ROlHL-08696-15 0004 Orthotopic heart transplantation ■
Transplantation immunology -Avian antibody studies
(chickens, rats, rabbits)
ROlHl-08696-15 0013 Orthotopic heart transplantation -
Transplantation immunology-Cardiac heterotransplantation
(rabbits, dogs)
POlHL-13108-09 0014 Clinical heart transplantation -
Platelets and coagulation in accelerated graft coronary
atherosclerosis
" POlHL-13108-09 0015 Clinical heart transplantation -
Antithymocyte globulin analysis and clinical effects
POlHL-13 108-09 0016 Clinical heart transplantation -
Total lymphoid irradiation for immune response (dogs)
P50HL-15061-07 0006 Response of lung to injury -
Complement synthesis by pulmonary macrophages (guinea
pigs, human)
P50HL-15061-07 0010 Response of lung to injury - An
animal model system for the study of bronchiolitis and its
sequellae (dogs)
P60HL-1 7269-04 0034 National heart and blood vessel
research and demonstration center - Immunologic
enhancement of cardiac allografts (mice)
** POlHL-17417-05 0004 Experimental lung transplantation
- Methods for suppressing lung allograft rejection (dogs,
mice)
POlHL-18646-03 0001 Studies basic to heart
transplantation - Individualized regulation of
immunosuppression (dogs, rats)
P01HL1864603 0006 Studies basic to heart
transplantation - Reduction or elimination of existing
presensitization (human, animals)
POIHL-1864603 0009 Studies basic to heart
transplantation ■ Pathologic aspects of cardiac allograft
rejection (sheep, dogs)
P50HL-19171-02 0007 Pulmonary SCOR-Lung injury by
childhood infections • Immunologic studies in models of
lower respiratory tract infection (rodents)
ROlHL-19711-03 Lymphokines in pulmonary granulomas
(guinea pigs)
ROlHL-20104-03 Pulmonary granulomatous inflammations
(mice)
lAAMUNITY, IMMUNOSUPPRESSION, RADIATION
IMMUNOSUPPRESSION
** ROlHL-0869615 0010 Orthotopic heart transplantation -
Transplantation immunology-Total lymphoid irradiation
(dogs, primates)
ROlHL-1398704 Transplantation of the luni; (dogs)
** ROlHL-18186-04 Cardiac allografts in autologous
radiation chimeras (rats, dogs)
lAAMUNITY, IMMUNOSUPPRESSIVE AGENTS
SEE ALSO IMMUNOLOGY, COMPLEMENT INHIBITORS
SEE ALSO IMMUNOLOGY, IMMUNOREGULATORY ALPHA
GLOBULIN
ROlHL-01803-23 0010 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Atherosclerosis induction-Graft rejection
and hypercholesterolemia (rabbits)
POlHL-0631217 0018 Surgical cardiology - Cardiac
transplantation growth (calves)
POlHL-06312-17 0028 Surgical cardiology - Coronary flow
in the transplanted denervated heart (dogs)
POlHL-06370-17 0001 Cardiopulmonary and renal
pathology research center The humoral and cellular
mechanisms of allograft rejection (monkeys)
POlHL-06370-17 0004 Cardiopulmonary and renal
pathology research center - Lymphocytes in graft rejection
and immune surveillance (human)
ROlHL-08696-15 0004 Orthotopic heart transplantation ■
Transplantation immunology-Avian antibody studies
(chickens, rats, rabbits)
298
ROlHL-08696-15 0013 Orthotopic heart transplantation -
Transplantation immunology-Cardiac heterotransplantation
(rabbits, dogs)
ROlHL-08696-15 0014 Orthotopic heart transplantation -
Transplantation immunology-Cardiac retransplantation
(dogs)
" ROlHL-08696-15 0019 Orthotopic heart transplantation •
Suppressor cell stimulation (dogs, mice)
R01HL08696-15 0020 Orthotopic heart transplantation -
Complete cardiopulmonary transplantation (dogs)
M POlHL-1310809 Clinical heart transplantation
POlHL-13108-09 0001 Clinical heart transplantation -
Therapy and prognosis (human)
P01HL13108-09 0014 Clinical heart transplantation ■
Platelets and coagulation in accelerated graft coronary
atherosclerosis
" POIHLI 3 108-09 0015 Clinical heart transplantation -
Antithymocyte globulin analysis and clinical effects
POIHL 1310809 0016 Clinical heart transplantation -
Total lymphoid irradiation for immune response (dogs)
P60HL- 15999-05 0008 Miami comprehensive sickle cell
center - Cyanate effect on host defense -Cellular and
humoral (human, guinea pig, rabbits)
ROlHL-162 19-05 Mechanisms of atherogenesis in chronic
uremia (human, rats)
POlHL-16387-04 0006 The blood vessel and
thrombogenesis - Mechanism of delayed vessel graft failure
(dogs, rabbits)
POIHL 1741705 0003 Experimental lung transplantation
- Methods for detecting lung allograft rejection (dogs)
ROlHL-1799304 0002 Ventricular dynamics from
surgically inserted markers - Left ventricle function in
human cardiac allograft
POlHL-18646-03 0001 Studies basic to heart
transplantation - Individualized regulation of
immunosuppression (dogs, rats)
POlHL-18646-03 0002 Studies basic to heart
transplantation - Detection of rejection (dogs)
POlHL-18646-03 0008 Studies basic to heart
transplantation - Immunophysiology and early detection of
rejection (dogs)
P01HL18646-03 0009 Studies basic to heart
transplantation - Pathologic aspects of cardiac allograft
rejection (sheep, dogs)
POlHL-1971702 0038 Response of the lung to injury -
Interstitial lung disease -Clinical, pathologic and
epidemiologic
POlHL-1971702 0039 Response of the lung to injury -
Lung scanning in alveolitis and asbestolic interstitial
pneumonia (human, animal)
" POlHL-197 17-02 0040 Response of the lung to injury ■
Immunosuppressive drugs in usual interstitial pneumonia
(human)
ROlHL-20063-03 Pathogenesis of pulmonary mycoplasma
infections (guinea pigs, mice)
** R23HL-21997-01 Pulmonary immunopathology in the
compromised host (guinea pigs)
** R23HL-22448-01 Modulation of heart graft antigenicity by
perfusion (rats)
IMMUNITY, ISOIMMUNITY
SEE TISSUE COMPATIBILITY-TRANSPLANT, ISOALLOIMMUNITY
IMMUNIZATION
SEE IMMUNITY, IMMUNIZATION (IMMUNOTHERAPY)
IMMUNIZATION ACTIVE
SEE IMMUNITY, IMMUNIZATION ACTIVE
IMMUNIZATION PASSIVE
SEE IMMUNITY, IMMUNIZATION PASSIVE
IMMUNOASSAY
SEE IMMUNOLOGICAL TESTS AND IMMUNOASSAY,
IMMUNOASSAY*
IMMUNOBIOLOGY STUDY SECTION
** ROlHL-18186-04 Cardiac allografts in autologous
radiation chimeras (rats, dogs)
IMMUNOCHEMISTRY
POIHL 06285-18 0186 Cardiovascular-respiratory
physiology and biochemistry • Leukocyte hormone receptors
and cyclic nucleotides (tissue culture)
POlHL-06350-17 0005 Hemostasis research program
project - Purification of plasma antihemophilic factor
(human)
ROlHL-07379-13 Structure and function of fibrinogen
(human)
ROlHL-10036-13 Biology of red cell antigen-antibody
reaction (human)
ROlHL-103 16-13 Structural studies on low density serum
lipoproteins (human)
ROlHL-10608-12 Digoxin-specific antibodies (human)
** P01HL-I131012 0096 Mechanisms of cardiovascular
disease - Complement chemistry and biology (human,
rabbits)
POlHL-113 10-12 0098 Mechanisms of cardiovascular
disease - Protein chemistry of thyl and related
synaptosomal proteins (mice)
ROIHL 12994 09 The Rh complex of red cells (human)
P50HL-141 53-07 0015 Johns Hopkins Lung Center-
Chronic diseases of airways - Kinins and human lung
•Excludes routine methodology OR covers only general p- jects which preclude indexing
•"Oriented significantly to above subject.
at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
lAAM
** P50HL-1419707 0008 Support for center of research on
arteriosclerosis - Core facility-Lipoprotein preparation,
immunochemistiy
POIHL 14388-07 0211 Regulation of the circulation In
pathological states - Choline acetyltransferase activity
(rats)
POIHL 14388-07 0212 Regulation of the circulation in
pathological states ■ Role of dopamine in autonomic
activity
*• P60HL-1 5 158-07 0020 Comprehensive sickle cell center -
Immunochemical investigation of hemoglobin variants
(human)
ROIHL 15474-06 Structure and function of the
antihemophilic factor (human, cattle)
M POIHL- 15486-06 Studies on thrombosis
** POlHL-1548606 0002 Studies on thrombosis
Characterization of antisera to fibrinopeptide B (human,
rabbits)
P01HL1548606 0003 Studies on thrombosis -
Mechanism and prevention of fibrinopeptide B degradation
(human)
POIHL 1548606 0004 Studies on thrombosis -
Thrombosis, intravascuair coagulation, platelet aggregation
(dogs)
ROIHL-15690-07 Hydrolytic enzymes of blood in health
and disease (human, animals)
POlHL-16251-06 0002 Membrane-bound enzymes in heart
and other tissues ■ Structural basis of regulation of
cardiac succinate dehydrogenase
POlHL-16411-04 0003 Blood systems in coagulation and
vessel disease ■ Molecular events involving the late stages
of coagulation (rabbits)
POlHL-16411-04 0006 Blood systems in coagulation and
vessel disease - Factor Vll-lmmunochemistry and
immunobiology (human, mice)
ROlHL-17552-03 Sickling inhibition by chemical
modification of hemoglobin (human)
ROlHL-17752-03 Purified human clotting factor IX-
Immunologic studies (human)
ROlHL-1833305 Thrombogenesis and hemostatic balance
(rabbits, human)
•* P50HL 18828-03 0001 Specialized center of research in
thrombosis - Membrane biology and hemostasis (human)
POlHL-18974-03 0010 Experimental neurogenic
hypertension program ■ Biochemistry and regulation of
PNMT in brain (rats)
ROlHL-19131-04 Hypercoagulability and assays for its
protection (human)
" ROlHL-19767-01 Pathochemistry of fibrinogen (humans)
ROlHL-20014-02 Radioimmunoassay of hyper and
hypocoagulable states (rabbits)
ROlHL-22270-01 Platelet glycoprotein (human)
R23HL-22448-01 Modulation of heart graft antigenicity by
perfusion (rats)
ROlHL-22456-01 Lipoproteins in bioregulation of the
immune response (mice, human)
ROlHL-22671-01 Removal of senescent and stored human
red cells
R23HL-22799-01 Interaction of the complement and
coagulation systems (monkeys)
ROIHL-23209-01 Autonomic receptors of the pulmonary
vasculature (mammals)
IMMUNOCYTE ADHERENCE TECHNIQUE
SEE IMMUNOLOGICAL TESTS AND IMMUNOASSAY, IMMUNE
ADHERENCE REACTION
IMMUNODIAGNOSIS (GENERAL)
SEE IMMUNOLOGICAL TESTS AND IMMUNOASSAY,
IMMUNOLOGICAL TESTS*
IMMUNODIFFUSION TEST
SEE IMMUNOLOGICAL TESTS AND IMMUNOASSAY
IMMUNODIFFUSION TESTS*
IMMUNOELECTROPHORESIS
SEE IMMUNOLOGICAL TESTS AND IMMUNOASSAY,
IMMUNOELECTROPHORESIS*
lAAMUNOFLUORESCENCE
SEE IMMUNOLOGICAL TESTS AND IMMUNOASSAY,
IMMUNOFLUORESCENCE*
IMMUNOGENETICS (GENERAL)
SEE ALSO BLOOD GROUPS
SEE ALSO TISSUE COMPATIBILITY-TRANSPLANT,
ISOALLOIMMUNITY
ROlHL-05351-18 Blood group antigens and antibodies
(human, rabbits, sheep)
POlHL-0631417 0050 Immunologic mechanisms in
cardiovascular disease Physiologic changes in
lymphocytes (human, mice)
** POlHL-06314-17 0059 Immunologic mechanisms in
cardiovascular disease - Immunogenetic response to
streptococcal antigens in man
POlHL-06314-17 0066 Immunologic mechanisms in
cardiovascular disease Sensitization, cell-mediated
cytotoxicity, role of lymphocytes (human, mice)
ROlHL-07379-13 Structure and function of fibrinogen
(human)
ROlHL-09163-13 Control mechanisms in hemostasis
(human)
POIHL 13108-09 0009 Clinical heart transplantation - B
cell alloantigens in cardiac allograft compatibility (human)
(contd)
IMM
R01H11398704 Ti»nsplant«tion o( the luciu (dogs)
PbOHl 1538907 0001 Pulmonary SCOR Hypersensitivity
pneumonitis Clinical studios ol liypersensitivity
pneumonitis
POIHL 1S832 06 0009 Chemical structural predispositions
to lunj Injury Immunology Eniyme degradation products
ol human lung elastin and microlibnl
•• POIHL 16411 04 0006 Blood systems in coagulation and
vessel disease Factor VII Immunochemistry and
immunobiology (human, mice)
POIHL 16/480S 0002 Cellular and Immunological basis
of pulmonary diseases Immunological function ol alveolar
macrophages (rabbits, sheep, mice)
M POIHL 16769 05 Pathobiologic and host defense reactions
in the lung
•* POIHL 16769 05 0007 Pathobiologic and host defense
reactions In the lung Immunogenetic factors in
sarcoidosis (human)
•* P60HL 1726504 0008 Community blood resource center
support Research- Blood genetic markers as biological
probes (human)
ROIHL 1771004 Selective replication of hemoglobin genes
(mice, ducks, human)
ROIHL 1930703 Problems in prevention of rheumatic
heart disease (human)
ROIHL- 19628-03 Mechanisms of pulmonary alveolar
proteinoses (human, rats)
ROIHL 1964603 An immunologic study of hemoglobin
variation in man
ROIHL 1987303 Pulmonary responses to inhaled antigen
(rabbits, guinea pigs)
** ROIHL 19984-02 Blood pressure and immunogenetic
factors in the young (human)
ROlHL-2006303 Pathogenesis of pulmonary mycoplasma
infections (guinea pigs, mice)
** ROlHL-22301-01 Immunogenetlcs of chronic pulmonary
inflammation (mice)
*• ROlHL-2363101 Immunogenetic factors In allergic
respiratory diseases (human)
ROlHL-23664-01 Selected topics on blood transfusion
(rabbits, human)
lAAMUNOGLOBULIN A
SEE GLOBULINS. GAMMA GLOBULINS. IMMUNOGLOBULIN A
IMMUNOGIOBUUN A, SECRETORY
SEE IMMUNOLOGY. SECRETORY (ANTIBODY) (FACTOR)
SYSTEM
IMMUNOGLOBULIN E
SEE GLOBULINS. GAMMA GLOBULINS. IMMUNOGLOBULIN E
IMMUNOGLOBULIN G
SEE GLOBULINS. GAMMA GLOBULINS. IMMUNOGLOBULIN G
IMMUNOGLOBULIN M
SEE GLOBULINS. GAMMA GLOBULINS. IMMUNOGLOBULIN M
lAAMUNOGLOBULIN STRUCTURE
SEE GLOBULINS. GAMMA GLOBULINS. IMMUNOGLOBULIN
STRUCTURE
IMMUNOGLOBULINS
SEE GLOBULINS, GAMMA GLOBULINS, IMMUNOGLOBULIN(S)
IMMUNOHEMATOLOGY (GENERAL)
SEE BLOOD AND RE SYSTEM. IMMUNOHEMATOLOGY
(GENERAL)
IMMUNOLOGIC DEFICIENCY DISORDERS
SEE IMMUNOPATHOLOGY. IMMUNOLOGIC DEFICIENCY
DISORDERS
IMMUNOLOGIC DISORDERS CHEMOTHERAPY
SEE IMMUNOPATHOLOGY. CHEMOTHERAPY
IMMUNOLOGIC DISORDERS DIAGNOSIS
SEE IMMUNOPATHOLOGY. DIAGNOSIS*
IMMUNOLOGICAL PARALYSIS
SEE IMMUNITY, IMMUNOLOGICAL UNRESPONSIVENESS
IMMUNOLOGICAL PREPARATIONS
(GENERAL)(INCIUDING CERTIFICATION AND
STANDARDIZATION)
SEE ALSO COMMUNICABLE DISEASE CONTROL AGENTS
SEE ALSO IMMUNITY, IMMUNIZATION (IMMUNOTHERAPY)
SEE ALSO IMMUNITY. IMMUNOSUPPRESSION. ALLOANTISERA
SEE ALSO IMMUNOLOGY. ANTIBODIES. IMMUNE SERA
SEE ALSO IMMUNOLOGY, ANTITOXINS
SEE ALSO TISSUE COMPATIBILITY-TRANSPLANTATION
RESOURCES, REFERRAL CENTERS AND
REGISTRIES
N01HB-62908-07 Maternal to infant transmission of
hepatitis 6 (human)
ROlHL-08696-15 0001 Orthotopic heart transplantation -
Transplantation Immunology-Antithymocyte globulin
(rabbits, monkeys)
P50HL-14197-07 0008 Support for center of research on
arteriosclerosis - Core facillty-Llpoprotein preparation,
immunochemistry
P50HL-15389-07 0014 Pulmonary SCOR -Hypersensitivity
pneumonitis - Fractionation and characterization of pigeon
antigens
299
P50HL 15389 0/ 0015 Pulmonary SCOR Hypersensitivity
pneumonitis fractionation and characteruation of
thoimophilic Actinomycete antigens
P50HL 15389 07 0019 Pulmonary SCOR Hypersensitivity
pneumonitis Microbiology core (human, animal)
POIHL 1674805 000? Cellular and immunological basis
of pulmonary diseases Immunological function of alveolar
macrophages (rabbits, sheep, mice)
•* POIHL 16769 05 0011 Pathobiologic and host defense
reactions in the lung Core Laboratory for biomedical
preparation (rabbits)
R01HL20104 03 Pulmonary granulomatous inflammations
(mice)
P60HL 20985-01 0002 Northern California sickle cell
center Immunization with polyvalent pneumococcal
polysaccharide vaccine (human)
IMMUNOLOGICAL PREPARATIONS, ADJUVANTS
IMMUNOLOGIC
ROIHL 08696-15 0004 Orthotopic heart transplantation -
Transplantation immunology -Avian antibody studies
(chickens, rats, rabbits)
IMMUNOLOGICAL PREPARATIONS, ADJUVANTS
IMMUNOLOGIC, FREUND'S ADJUVANT
** ROIHL 1974603 Proliferation and differentiation of
alveolar macrophages (mice, hamsters)
IMMUNOLOGICAL PREPARATIONS, TOXOIDS,
TETANUS TOXOID
POIHL 1925903 0003 Digoxinspeclfic antibody in human
therapy ■ Synthesis of dogoxin-specific antibody in
continuous cell culture (human, sheep)
IMMUNOLOGICAL SCIENCES STUDY SECTION
** R23HL-21089-02 Localization of mediators in dispersed
lung cells (guinea pigs, human)
** ROlHL-22301-01 Immunogenetlcs of chronic pulmonary
inflammation (mice)
** ROlHL-22456-01 Lipoproteins in bioregulation of the
immune response (mice, human)
** ROIHL 22582-01 Pulmonary and circulatory alterations
induced by IGE
** ROlHL-23631-01 Immunogenetic factors In allergic
respiratory diseases (human)
** ROlHL-23654-01 Selected topics on blood transfusion
(rabbits, human)
IMMUNOLOGICAL TESTS
SEE IMMUNOLOGICAL TESTS AND IMMUNOASSAY,
IMMUNOLOGICAL TESTS*
IMMUNOLOGICAL TESTS AND IMMUNOASSAY,
HEMAGGLUTINATION*
ROIHLI 11 54-12 Blood group antigens and antibodies
(human)
ROlHL-12994-09 The Rh complex of red cells (human)
** ROlHL-14637-05 Thrombopoietln-lmmunoassay and
characterization (mice)
IMMUNOLOGICAL TESTS AND IMMUNOASSAY,
HEMAGGLUTINATION INHIBITION*
ROlHL-10567-12 Erythropoietin-Immunoassay and
characterization (dogs)
** R01HL14637-05 Thrombopoietin -Immunoassay and
characterization (mice)
IMMUNOLOGICAL TESTS AND IMMUNOASSAY,
IMMUNE ADHERENCE REACTION
POlHL-06370-17 0018 Cardiopulmonary and renal
pathology research center - Cytochemistry and Immunology
of lymphoproliferatlve disorders (human)
ROlHL-21565-02 Pathogenesis of Inflammatory lung Injury
(rats, rabbits)
ROlHL-2245601 Lipoproteins in bioregulation of the
Immune response (mice, human)
IMMUNOLOGICAL TESTS AND IMMUNOASSAY,
IMMUNOASSAY*
SEE ALSO BIOASSAY*
SEE ALSO OPTICS, MICROSCOPY, IMMUNE ELECTRON*
SEE ALSO PHYSICAL SEPARATION, CHROMATOGRAPHY.
AFFINITY
** ROlHL-13626-06 Lipoprotein lipase and lipoprotein
removal (human, rats, bacteria)
** POlHL-14388-07 9002 Regulation of the circulation in
pathological states - Core immunoassay laboratory (rabbits)
P50HL- 183 18-03 0003 Pathogenesis and complications of
hypertension - Core biochemical laboratory
R23HL-2 12 34-02 The regulation of cardiac hypertrophy
(rabbits)
R23HL-21421-01 Myocardial and vascular contractility and
cyclic nucleotides (cattle, rats)
IMMUNOLOGICAL TESTS AND IMMUNOASSAY,
IMMUNODIFFUSION TESTS*
** P60HL-151 60-07 0013 Center for sickle cell disease -
Immunochemical diagnosis of hemoglobinopathies (Infants)
P50HL-191 57-02 0007 Studies In cystic fibrosis and
bronchiolitis - Analysis of cystic fibrosis factors (human)
IMMUNOLOGICAL TESTS AND IMMUNOASSAY,
IMMUNOCIECTROPHORESIS*
ROIHI 15125 0/ Molecular pathology ol genflic duoidtri
in man
IMMUNOLOGICAL TESTS AND IMMUNOASSAY,
IMMUNOFLUORESCENCE
POIHL 1/41705 0001 Expeiimental lung tianiplantatioii
Mechanisms and mediators ol lung allograft ranction
(dogs, mice)
P50HL 1766904 0011 Ischemic heart disease center
(SCOR) Lysosomal function and lysosomal enzymes in
normal and ischemic heart (rabbit)
IMMUNOLOGICAL TESTS AND IMMUNOASSAY,
IMMUNOLOGICAL TESTS*
SEE ALSO HYPERSENSITIVITY TESTS
•• P50HL 15389 0' 0017 Pulmonary SCOR -HyperMnsitivity
pneumonitis Immunology core (human)
** POIHL 1857603 0014 Thrombosis research program
project Immunology core
POIHL 1864603 0001 Studies basic to heart
transplantation Individualized regulation of
immunosuppression (dogs, rats)
ROIHL 22026-01 Endogenous prostaglandins in asthma
IMMUNOLOGICAL TESTS AND IMMUNOASSAY,
PEROXIDASE LABELED ANTIBODY*
** POlHL-06314 17 0048 Immunologic mechanisms in
cardiovascular disease ■ Pathogenesis of glomerulonephrHi*
(rats, mice)
lAAMUNOLOGICAL TESTS AND IMMUNOASSAY,
RADIOIMMUNOASSAY*
POIHL 03174-23 0006 Mechanisms of acute vascular
reaction to Injury - Atherosclerotic plaque studies using
mosaic analysis (human)
ROlHL-08506 15 Lipemia-carbohydrate and glyceride
metabolism (human, rats)
POlHL-09011-15 0005 A research and resource program
in blood Characterization of hepatitis-B antigen and tlie
cause of serum hepatitis (human)
** ROlHL-10567-12 Erythropoietin-Immunoassay and
characterization (dogs) .
POlHL-1167811 0046 Cardiovascular dynamics and their
control - Regulation of aldosterone secretion and related
factors (dogs) .
POIHLI 1678-11 0066 Cardiovascular dynamics and their
control Closed-loop analysis of the aldosterone control
system (dogs) .
** POlHL-11578-11 9002 Cardiovascular dynamics and ttreif
control - Core-Radloimmunoassay and chemical laboratory
ROlHL-13885-08 9002 Cystic fibrosis and pulmonary
disease - Computer core facility (human)
P50HL-14236-C5 0003 Prevention of premature
arteriosclerosis - Intravascular clotting in patients with
hyperlipldemia
ROlHL-14306-07 Quantification of arterial pressure control
(dogs)
** P50HL- 15062-07 0013 Study of lipoproteins, artery vrall.
and atherosclerosis - Radioimmunoassay of apolipoproteins
(human, monkeys)
P50HL-15062-07 0021 Study of lipoproteins, artery wall,
and atherosclerosis - Core laboratories
P60HL-15158-07 0020 Comprehensive sickle cell center -
Immunochemical investigation of hemoglobin variants
(human)
ROlHL-15263-06 Lecithin-Cholesterol acetyltransferase
(human, rabbits)
** ROlHL-15308-07 Assays for peptides of lipoproteins
(human)
P5aHL-l 5389-07 0010 Pulmonary SCOR-Hypersensitivity
pneumonitis - Clinical study-Pulmonary lesions due to non-
invasive aspergillosis
** POIHL- 15486-06 0001 Studies on thrombosis - Studies on
chemistry of fibrinogen (human, dogs)
** POIHL 15486-06 0002 Studies on thrombosis -
Characterization of antisera to fibrinopeptide B (human,
rabbits)
POlHL-15486-06 0004 Studies on thrombosis -
Thrombosis, Intravascuair coagulation, platelet aggregation
(dogs)
POlHL-15486-06 0005 Studies on thrombosis • Isolation
and characterization of PF4 antigens (rabbits)
ROlHL-15528-05 Renin kinetics in hypertensive and
uremic plasma (human, dogs)
" POlHL-15596-05 0001 Coagulation, fibrinolysis,
hemostasis and hepatitis - Defibrination (human)
** POlHL-15596-05 0002 Coagulation, fibrinolysis,
hemostasis and hepatitis - Radioimmunoassay of
fibrinogen and fibrin derivatives (human)
POlHL-15835-06 0002 Study of muscles related to heart
disease ■ Proteins of smooth muscle system (cattle,
rabbits)
POIHL 1611806 0004 Study of emphysema Metabolic
activity of pulmonary connective tissue (human, hamsters)
R01HL-17366-a5 Mechanisms in the production of renal
hypertension (rabbits, dogs)
** POlHL-17430-05 0006 Control of coagulation - Activation
fragments of prothrombin in vitro and in vivo (human,
dogs, cattle)
ROlHL-17551-04 Biosynthesis and metabolism of
procollagen (human, monkeys, mice)
(contd)
•Excludes routine methodology OR covers only general projects which preclude
"Oriented significantly to above subject.
indexing at the specific level.
M Grant has subpraiects describing specific research aspects.
See Appendix for investigator's name and grant number.
IMM
P50HL-17646-04 0007 Study of ischemic heart disease •
Prediction of myocardial ischemic injury by analysis of
plasma CPK isoenzymes
** P50HL-1 7665-04 0011 Study of ischemic heart disease ■
Development of new methods for the determination of
infarct size (dog, human)
P50HL-1 7665-04 0032 Study of ischemic heart disease -
Myocardial infarct sizing -Immunoassay for cardiac myosin
light chains (dogs)
** P50HL-1 7669-04 0001 Ischemic heart disease center
(SCOR) - Radioimmunoassays lor CPK isoenzyme and
myoglobin (human, dog)
** P50HL- 17669-04 0002 Ischemic heart disease center
(SCOR) - Myocardial infarction sizing by radioimmunoassay
of cardiac myosin (dogs)
P50HL-17669-04 0023 Ischemic heart disease center
(SCOR) - Patients with acute myocardial infarction and
myocardial ischemia (human)
ROlHL-18019-04 The endocrine kidney in hypertension
(mice)
ROIHL- 1802 7-03 New vasoactive factors and their role in
hypertension (human, dogs, rats)
R01HL-18095-04 Human dopamine-beta-hydroxylase (also
cattle)
P50HL- 183 18-03 0003 Pathogenesis and complications of
hypertension - Core biochemical laboratory
P50HL-18323-04 0033 SCOR hypertension center - Core
laboratory-Renin, aldosterone and bradykinin methodology
** ROlHL-18561-03 Radioimmunoassay of angiotensinogen
(human)
** ROlHL-18567-03 A routine diagnostic test for minimal
heart damage (human, rat)
ROlHL-18730-03 Role of mincralocorticoids in low renin
hypertension (human, rats)
ROlHL-19428-03 Role of angiotensin sensitivity in renin
release (human)
** R23HL-21328-02 The I blood group antigen of human
erythrocyte membrane
ROlHL-21779-01 Steroids in adrenal regeneration
hypertension (rats)
** ROlHL-22026-01 Endogenous prostaglandins in asthma
ROlHL-22208-02 Elastin structure, fibrogenesis and
disease (chickens, rabbits)
ROlHL-22585-01 Plasma proteins adsorbed to artificial
organs (human, rabbits)
POlHL-22602-01 0001 Pathophysiology of the
endothelium - Platelet-endothelial interactions in vitro
(human, cattle)
ROlHL-22618-01 Role of apolipoproteins in
hypertriglyceridemia (human)
** POlHL-226 19-01 0012 Cellular mechanisms of heart
failure - Apolipoproteins in hypertriglyceridemia (human)
IMMUNOLOGICAL UNRESPONSIVENESS
SEE IMMUNITY, IMMUNOLOGICAL UNRESPONSIVENESS
IMMUNOLOGY (GENERAL)
SEE ALSO ALLERGY AND IMMUNOLOGY STUDY SECTION
SEE ALSO BLOOD AND RE SYSTEM, IMMUNOHEMATOLOGY
(GENERAL)
SEE ALSO BLOOD GROUPS
SEE ALSO HYPERSENSITIVITY (GENERAL)
SEE ALSO IMMUNOPATHOLOGY (GENERAL)
SEE ALSO NEOPLASMS IMMUNOLOGY
SEE ALSO PREGNANCY IMMUNOLOGY
SEE ALSO TISSUE COMPATIBILITY-TRANSPLANT,
ISOALLOIMMUNITY
ROlHL-02751-21 Function and metabolism of serum
albumin (mammals, fish, amphibians)
ROlHL-13909-27 Physiochemistry and immunology of
macromolecules
P50HL-14164-07 0043 A/S SCOR-Comparative and
experimental atherosclerosis - Electron microscopy resource
laboratory
M POlHL-1741705 Experimental lung transplantation
ROlHL-18095-04 Human dopamine-beta-hydroxylase (also
cattle)
POlHL-20994-02 9001 Dynamics of neutrophil elastase in
the lung - Biochemistry and immunology core
lAAMUNOLOGY, ACUTE PHASE PROTEINS
P60HL 17265-04 0003 Community blood resource center
support - Research-Human factor IX -Role in intrinsic
clotting (also baboons, dogs)
P01HL18574-03 0004 Lipoprotein methodology and
biomedical applications - Fine structure and metabolism of
lipoproteins -EM studies (guinea pigs)
ROlHL-23161-01 0005 Biology of myocardial ischemia -
Localization of complement in myocardial infarction (dog)
IMMUNOLOGY, ANTIBODIES
SEE ALSO BLOOD GROUPS ISOANTIBODIES
SEE ALSO GLOBULINS, GAMMA GLOBULINS,
IMMUNOGLOBULIN(S)
SEE ALSO GLOBULINS, GAMMA GLOBULINS,
IMMUNOGLOBULIN STRUCTURE
SEE ALSO HYPERSENSITIVITY, SENSITIZING ANTIBODIES
HUMORAL
SEE ALSO HYPERSENSITIVITY, SENSITIZING ANTIBODIES NON-
HUMORAL
SEE ALSO HYPERSENSITIVITY, SKIN SENSITIZING ANTIBODY
SEE ALSO IMMUNOLOGY, ANTITOXINS
SEE ALSO IMMUNOPATHOLOGY, AUTOANTIBODIES
SEE ALSO NEOPLASMS IMMUNOLOGY, TUMOR ANTIBODIES
300
SEE ALSO TISSUE COMPATIBILITY-TRANSPLANT,
ISOALLOANTIBODIES
R01HL-07652 14 Destruction of red blood cells in
hemolytic anemias (human, guinea pigs)
P01HL-09011-15 0013 A research and resource program
in blood - A quantitative study of immunological
enhancement (mice)
ROlHL-10608-12 Digoxin-specific antibodies (human)
POlHL-12157-11 0033 Functions and mechanisms of cell
membrane ion transport Immunology aspects of active
Na-K transport in sheep red cell (also human, mice)
ROIHL-12524-10 Reaction of hemoglobin with ligands and
antibodies (human, carp)
P50HL-14230-07 0095 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Blood platelet adherence to endothelial
smooth muscle cells, fibroblast (human)
P50HL-14230-07 0096 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Ultrastructural studies of endothelial cells
(human)
ROlHL-15341-06 Lung hormonal and chromosomal
regulation (rats, rabbits)
POIHL 16118-06 0003 Study of emphysema Degradation
of collagen and elastin (human, hamsters, mice)
ROlHL-16626-05 Studies of antibodies to antihemophilic
factors (human, rabbits)
P60HL- 172 65-04 0002 Community blood resource center
support - Research-Human factor VIII
P50HL-17669-04 0002 Ischemic heart disease center
(SCOR) • Myocardial infarction sizing by radioimmunoassay
of cardiac myosin (dogs)
POlHL-1 78 13-04 0008 Lung disease and the oxygenation
of blood and tissue - Pulmonary regulation of systemic
blood pressure (human, rabbits, rats)
ROlHL-18003-05 Digitalis-Mechanism and reversal studies
(dog, sheep, duck, guinea pig, human)
P50HL-18323-04 0033 SCOR hypertension center - Core
laboratory-Renin, aldosterone and bradykinin methodology
ROlHL-191 29-04 Cardiac glycosides-Mechanisms of
cellular actions
POlHL-19259-03 Digoxin-specific antibody in human
therapy
POlHL-19259-03 0003 Digoxin-specific antibody in human
therapy - Synthesis of dogoxin-specific antibody in
continuous cell culture (human, sheep)
ROlHL-19628-03 Mechanisms of pulmonary alveolar
proteinoses (human, rats)
ROlHL-21274-01 Prorenin-Physiological and biochemical
analysis (human)
ROlHL-21394-02 Pulmonary angiotensin-converting enzyme
(rabbits)
ROlHL-21751-02 Thallium and antimyosin in ischemia and
infarction
Thallium and antimyosin in
- In vitro models of ischemia and
Thallium and antimyosin in
- Canine models of ischemia and
Thallium and antimyosin in
Human studies-Ischemia and
Immunologic mechanisms in
Glomerular cells in tissue culture
ROlHL-21751-02 0001
ischemia and infarction
infarction (rats, mice)
ROlHL-21751-02 0002
ischemia and infarction
infarction
ROlHL-21751-02 0003
ischemia and infarction
infarction
R23HL-21918-01 Hypersensitivity pneumonitis in guinea
pigs
lAAMUNOLOGY, ANTIBODIES, AGGLUTININS
ROlHL-20971-10 Membrane glycoproteins of platelets and
leukocytes (human)
IMMUNOLOGY, ANTIBODIES, ANTI-ANTIBODIES
POlHL-063 14-17 0047 Immunologic mechanisms in
cardiovascular disease - Role of intravascular coagulation
(human, animals)
POlHL-063 14-17 0063
cardiovascular disease -
(human)
ROlHL-15124-05 Genesis of hypertension in renal disease
(human, dogs)
POlHL-16769-05 0002 Pathobiologic and host defense
reactions in the lung - Pathogenesis of complement
dependent injury to the lungs (rabbits)
POlHL-18208-04 0003 Center for the study of blood cell
rheology - Bone marrow microcirculation (rats, mice)
POlHL-18576-03 0007 Thrombosis research program
project - Relationships between coagulability and
thrombosis (human, animals)
** POIHL- 192 59-03 0001 Digoxin-specific antibody in human
therapy - Primary structure of monoclonal antibodies
(rabbits)
** POlHL-19259-03 0002 Digoxin-specific antibody in human
therapy - Chemical semi-synthesis of digoxin-specific
antibody (rabbits)
** POIHL- 192 59-03 0003 Digoxin-specific antibody in human
therapy - Synthesis of dogoxin-specific antibody in
continuous cell culture (human, sheep)
** POlHL-19259-03 0004 Digoxin-specific antibody in human
therapy • Digitalis-specific antibodies pharmacological
studies (human, dogs, sheep)
ROlHL-19977-02 Genesis of circulatory shock by
pancreatic peptides (cats, dogs)
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojects describing specific researcli aspects.
See Appendix for investigator's name and grant number.
IMM
IMMUNOLOGY, ANTIBODIES, BLOCKING
ANTIBODIES
P60HL-1 7269-04 0034 National heart and blood vessel
research and demonstration center - Immunologic
enhancement of cardiac allografts (mice)
IMMUNOLOGY, ANTIBODIES, HEMAGGLUTININS
SEE ALSO PLANTS PROTEINS, LECTINS
ROlHL-05351-18 Blood group antigens and antibodies
(human, rabbits, sheep)
IMMUNOLOGY, ANTIBODIES,
HEMAGGLUTININS, LEUKO-AGGLUTININS
NOlHB-62973-05 Collection, function and transfusion of
granulocytes
lAAMUNOLOGY, ANTIBODIES, lAAMUNE SERA
SEE ALSO GLOBULINS, SERUM GLOBULINS
SEE ALSO HYPERSENSITIVITY, SENSITIZING ANTIBODIES
HUMORAL
SEE ALSO IMMUNOLOGY, ANTITOXINS
SEE ALSO IMMUNOLOGY, PROPERDIN
SEE ALSO MICROBIAL IDENTIFICATION AND CLASSIFICATION,
SEROTYPING
NOIHI 32926-10 Analysis of lipoproteins (animals)
P01HL-06314-17 0060 Immunologic mechanisms in
cardiovascular disease - Strept antigens and infections in
cardiovascular complications (human, animals)
POlHL-06835-17 0026 Cardiovascular disease -
Lipoproteins (human, guinea pig)
POlHL-11310 12 0097 Mechanisms of cardiovascular
disease - Structural-functional relationships of neuronal
differential alloantigens (mice)
POlHL-121 57-11 0055 Functions and mechanisms of cell
membrane ion transport - Growth and development of
synthetic strand heart cells in culture (chick embryo)
P50HL-14197-07 0008 Support for center of research on
arteriosclerosis Core facility-Lipoprotein preparation,
immunochemistry
ROlHL-14262-07 Leukocyte proteases and their lung
targets (human, dogs, rabbits)
P50HL-15062-07 0013 Study of lipoproteins, artery wall,
and atherosclerosis - Radioimmunoassay of apolipoproteins
(human, monkeys)
P60HL-15158-07 0020 Comprehensive sickle cell center -
Immunochemical investigation of hemoglobin variants
(human)
P60HL-15160-07 0013 Center for sickle cell disease -
Immunochemical diagnosis of hemoglobinopathies (infants)
** POIHL- 15486-06 0002 Studies on thrombosis -
Characterization of antisera to fibrinopeptide B (human,
rabbits)
POlHL-15832-06 0010 Chemical-structural predispositions
to lung injury - Kinin generating systems in pulmonary
disease (human, animals)
P60HL-15999-05 0020 Miami comprehensive sickle cell
center - Deficiency in complement-dependent humoral
immunity-Sickle cell disease (human)
ROlHL-16720-02 Platelet aggregation (human)
POlHL-16748-05 0002 Cellular and immunological basis
of pulmonary diseases - Immunological function of alveolar
macrophages (rabbits, sheep, mice)
POlHL-16769-05 0004 Pathobiologic and host defense
reactions in the lung - Pathogenesis of Pseudomonas and
Serratia pneumonias (rabbits)
ROlHL-17243-05 Cause of chronic experimental renal
hypertension (dogs, rabbits)
R01HL-I7752-03 Purified human clotting factor IX-
Immunologic studies (human)
ROlHL-18567-03 A routine diagnostic test for minimal
heart damage (human, rat)
ROIHL 19633-02 Pathogenesis and pharmacology of lung
fibrosis (rats, rabbits)
ROlHL-22302-01 Immune responses in the human lung
(also rabbits, monkeys)
ROlHL-23654-01 Selected topics on blood transfusion
(rabbits, human)
IMMUNOLOGY, ANTIBODIES, OPSONINS
SEE ALSO IMMUNOLOGY, PROPERDIN
POlHL-06314-17 0060 Immunologic mechanisms in
cardiovascular disease - Strept antigens and infections in
cardiovascular complications (human, animals)
POlHL-08682-15 0019 Regulation of the cardiovascular
system - Hepatic immunophysiology and host-defense in
shock (rat, dog, human)
P50HL-15061-07 0007 Response of lung to injury -
Human factors for phagocytosis in normal and diseased
lungs
P50HL-15O61-07 0009 Response of lung to injury -
Alveolar macrophages (human, rabbits)
•* P60HL-15160-07 0014 Center for sickle cell disease -
Replacement therapy of opsonin deficiency in sickle cell
anemia (children)
P60HL-15169-05 0009 Support for center for sickle cell
disease - Infections in sickle cell anemia (human)
P60HL15996-06 0003 Cincinnati comprehensive sickle
cell center Prophylactic penicillin in treatment of sickle
cell anemia (human)
P60HL-15999-05 0008 Miami comprehensive sickle cell
center - Cyanate effect on host defense-Cellular and
humoral (human, guinea pig. rabbits)
(contd)
• P60HL1599905 0020 Mi«mi comprehensive sicMe cell
center Deficiency in complement dependent humoriil
immunity Sickle cell disease (humen)
P50HL 19171 02 0007 Pulmonary SCOR Lung iniury by
childhood infections Immunologic studies in models of
lower respiratory tract infection (rodents)
ROIHL 19237 03 Obstructive lung disease and alveolar
macrophages (human, animals)
P60HL 20985 01 0002 Norlhem California sicKle cell
center Immunization with polyvalent pneumococcal
polysaccharide vaccine (human)
ROIHL 22302 01 Immune responses in the human lung
(also rabbits, monkeys)
IMMUNOLOGY, ANTIBODIES BACTERIAl
P60HL lbl6207 0021 Comprehensive sickle cell center ■
Pneumococcal vaccine in sickle cell disease (children)
P50HL 1538907 0011 Pulmonary SCOR- Hypersensitivity
pneumonitis Animal model- Hypersensitivity pneumonitis
in rabbits
POlHL-16748-05 0004 Cellular and immunological basis
of pulmonary diseases Cellular and immunological
processes in pulmonary defense systems
POlHL-16769-05 0008 Pathobiologic and host defense
reactions m the lung Pulmonary immunocytologic defense
mechanisms against bacteria (human, animals)
ROlHL-17751-03 Experimental endocarditis (rabbits)
ROlHL-20533-09 Pathogenesis of rheumatic fever (human,
rabbits)
IMMUNOLOGY, ANTIBODIES FUNGAL
PSOHL 1538907 0010 Pulmonary SCOR -Hypersensitivity
pneumonitis Clinical study-Pulmonary lesions due to non-
invasive aspergillosis
IMMUNOLOGY, ANTIBODIES VIRAL
P50HL-1413607 0003 Pulmonary SCOR -Airways
obstructive diseases - Acute pediatric respiratory disease
and COLD
ROlHL-16246-06 Immunologic studies m
postpericardiotomy syndrome (human)
" P50HL-19157-02 0011 Studies in cystic fibrosis and
bronchiolitis - Pathogenesis of bronchiolitis (children)
ROlHL-23631-01 Immunogenctic factors in allergic
respiratory diseases (human)
IMMUNOLOGY, ANTIBODY FORMATION
ROlHL-01803-23 0021 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Induction of IgE antibodies to antigen
from tobacco and cigarette smoke (rabbits)
P01HL06314-17 0048 Immunologic mechanisms in
cardiovascular disease - Pathogenesis of glomerulonephritis
(rats, mice)
POlHL-08805-15 0049 Regulation of ventilation and
pulmonary circulation - Pulmonary hypertension produced
by Oirofilaria immitis in the dog
POlHL-12157-11 0055 Functions and mechanisms of cell
membrane ion transport - Growth and development of
synthetic strand heart cells in culture (chick embryo)
POlHL-13108-09 0012 Clinical heart transplantation ■
Human T cell sheep erythrocyte receptors
P50HL-14136-07 0003 Pulmonary SCOR-Airways
obstructive diseases - Acute pediatric respiratory disease
and COLD
P50HL-14212-07 0015 Correlated studies of pulmonary
fibrosis - Pulmonary defense mechanisms and fibrotic lung
disease (rodents, rabbits)
P50HL-1 5389-07 0010 Pulmonary SCOR-Hypersensitivity
pneumonitis - Clinical study -Pulmonary lesions due to non-
invasive aspergillosis
P50HL-15389-07 0012 Pulmonary SCOR-Hypersensitivity
pneumonitis - Animal model-lmmunologic lung disease in
guinea pigs
POlHL-15486-06 0002 Studies on thrombosis -
Characterization of antisera to tibrinopeptide B (human,
rabbits)
POlHL-15832-06 0002 Chemical-structural predispositions
to lung injury - Connective tissue in lung in development
and repair of injury (human, rats, mice)
POlHL-15832-06 0004 Chemical-structural predispositions
to lung injury - Proteolytic activity leucocytes in patients
with obstructive lung disease
POlHL-15832-06 0009 Chemical-structural predispositions
to lung injury - Immunology-Enzyme degradation products
of human lung elastin and microfibril
ROlHL-16246-06 Immunologic studies in
postpericardiotomy syndrome (human)
ROlHL-16626-05 Studies of antibodies to antihemophilic
factors (human, rabbits)
M POlHL-16748-05 Cellular and immunological basis of
pulmonary diseases
** POlHL-1674805 0002 Cellular and immunological basis
of pulmonary diseases ■ Immunological function of alveolar
macrophages (rabbits, sheep, mice)
P01HL16748-05 0004 Cellular and immunological basis
of pulmonary diseases ■ Cellular and immunological
processes in pulmonary defense systems
ROlHL-17751-03 Experimental endocarditis (rabbits)
** ROlHL-17752-03 Purified human clotting factor IX-
Immunologic studies (human)
ROIHl-18997-02 Ischemic therapy in experimental
hypersplenism (rats, dogs)
301
POIHL 19259-03 0003 Oigoxin specific antibody in human
therapy Synthesis of dogoxin specific antibody in
continuous cell culture (human, sheep)
ROIHL 19651 03 Host (actors in pathogenesis ot
respiratory disease (human, hamsters)
POIHI 19717 02 0037 Response of the lung to iniury
Catecholamines, prostaglandins and nucleotides in
pulmonary function (animals)
ROIHL 19873 03 Pulmonary responses to inhaled antigen
(rabbits, guinea pigs)
ROIHL 20086 02 Circulatory control ol splenic function
(rats)
ROIHL 20533 09 Pathogenesis of rneumatic fever (human,
rabbits)
P60HL 20985 01 0002 r<orthern California sickle cell
center Immunization with polyvalent pneumococcal
polysaccharide vaccine (human)
ROIHL 2182901 Etiology of obstructive airway disease in
children (also monkeys)
ROIHL 21995-01 Protein phosphorylation and adrenergic
effects
ROlHL-22301 01 Immunogenetics of chronic pulmonary
inflammation (mice)
ROlHL-22302 01 Immune responses in the human lung
(also rabbits, monkeys)
ROIHL 22456 01 Lipoproteins in bioregulation of the
immune response (mice, human)
** ROIHL 22582-01 Pulmonary and circulatory alterations
induced by IGE
IMMUNOLOGY, ANTIBODY SPECIFICITY
P60HL-151 58-07 0020 Comprehensive sickle cell center
Immunochemical investigation of hemoglobin variants
(human)
P60HL-15999-05 0019 Miami comprehensive sickle cell
center - Fetal-adult hemoglobin switch (mouse, monkey)
POlHL-17417-05 0001 Experimental lung transplantation
- Mechanisms and mediators of lung allograft rejection
(dogs, mice)
P50HL-17665-04 0011 Study of ischemic heart disease -
Development of new methods for the determination of
Infarct size (dog, human)
P50HL-17665-04 0032 Study of ischemic heart disease -
Myocardial infarct sizing-lmmunoassay for cardiac myosin
light chains (dogs)
POIHL- 192 59-03 0002 Digoxin-specific antibody in human
therapy - Chemical semi-synthesis of digoxin-specific
antibody (rabbits)
R01HL19651-03 Host factors in pathogenesis of
respiratory disease (human, hamsters)
ROlHL-19733-03 Absorption of antigen through inflamed
lungs (rabbits)
R01HL-20086-02 Circulatory control of splenic function
(rats) ^ .,
ROlHL-21874-01 SRS-A-lts biosynthesis and action
IMMUNOLOGY, ANTIGEN-ANTIBODY
REACTIONS
SEE ALSO IMMUNOLOGICAL TESTS AND IMMUNOASSAY,
HEMAGGLUTINATION*
SEE ALSO IMMUNOLOGY. SEROLOGY*
POlHL-031 74-23 Mechanisms of acute vascular reaction
to injury
POlHL-03174-23 0005 Mechanisms of acute vascular
reaction to injury - Renal small vessel didease -Cell and
matrix response (human, mice)
POlHL-063 14-17 0048 Immunologic mechanisms in
cardiovascular disease ■ Pathogenesis of glomerulonephritis
(rats, mice)
ROlHL-08399-15 Platelet injury in infections and allergic
diseases (human)
** R01HL-10036-13 Biology of red cell antigen-antibody
reaction (human)
ROlHL-11154-12 Blood group antigens and antibodies
(human)
ROlHL-12994-09 The Rh complex of red cells (human)
POlHL-13108-09 0013 Clinical heart transplantation -
Cardiomyopathic lymphocyte responsiveness to cultured
endothelium
P50HL-15389-07 0011 Pulmonary SCOR -Hypersensitivity
pneumonitis - Animal model-Hypersensitivity pneumonitis
in rabbits . ,^
P50HL-15389-07 0017 Pulmonary SCOR -Hypersensitivity
pneumonitis - Immunology core (human)
POlHL-16769-05 0002 Pathobiologic and host defense
reactions in the lung - Pathogenesis of complement
dependent injury to the lungs (rabbits)
P60HL-17265-04 0002 Community blood resource center
support - Research-Human factor VIII
P60HL-17269-04 0033 National heart and blood vessel
research and demonstration center - Autoallergic response
in cardiomyopathy, atherosclerosis, rheumatic heart disease
ROlHL-17322-04 Functional characteristics of smooth
muscle isolated from lung (animals)
POlHL-17382-05 0002 Chemical mediators of acute
pulmonary disorders ■ Chemical mediators and respiratory
mechanics in guinea pigs
POlHL-174 17-05 0003 Experimental lung transplantation
- Methods for detecting lung allograft reiection (dogs)
P50HL-17665-04 0011 Study of ischemic heart disease -
Development of new methods for the determination of
infarct size (dog. human)
(MM
ROIHI 18535 03 Epidemiology ind coutM of viral
myopericardilis (human)
P50HL 18828 03 0003 Specialized center of research in
thrombosis Structure and function o( pla^ma coagulation
inhibitors (human)
P50HL 19156 02 0005 Pulmonary SCOR Chronic di»e»»e»
of airways Vagal receptors m the airway [pilhelial in)ury
and antigen (dog. cat. rabbit)
P50HL 19171 02 000/ Pulmonary SCOR Lung m)ury by
childhood infections Immunologic studies in models of
lower respiratory tract infection (rodents)
ROIHL 19456 03 Immunoglobulins associated with serum
hyperviscosity (human)
P01HL19717 02 0037 Response ol the lung to in)ury
Catecholamines, prostaglandms and nucleotides in
pulmonary function (animals)
ROIHL 2008602 Circulatory control of splenic function
(rats) ^ .
ROIHL 20711 01 Structure function relationships in reo
cell NA K pumps (goats)
ROIHL 20875-02 Chronic obstructive pulmonary disease-
Familial/genetic (human)
ROlHL-21565-02 Pathogenesis of inflammatory lung injury
(rats, rabbits)
ROIHL 22505-01 Molecular pathology of fibrinogen and
factor Xlll (human, animals)
ROIHL 23654-01 Selected topics on blood transfusion
(rabbits, human)
IMMUNOLOGY, ANTIGEN-ANTIBODY
REACTIONS, IMMUNE COMPLEXES
SEE ALSO BLOOD PLATELETS. PLATELET AGGREGATION
SEE ALSO HYPERSENSITIVITY. SERUM SICKNESS
** ROlHL-01803-23 0021 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Induction of IgE antibodies to antigen
from tobacco and cigarette smoke (rabbits)
ROlHL-16626-05 Studies of antibodies to antihemophilic
factors (human, rabbits)
** ROlHL-16645-05 Pathobiology of thromboembolic disorders
(human)
POlHL-17417-05 0001 Experimental lung transplantation
- Mechanisms and mediators of lung allograft reiection
(dogs, mice)
IMMUNOLOGY, ANTIGENS
SEE ALSO BLOOD GROUPS ANTIGENS
SEE ALSO HYPERSENSITIVITY. ALLERGENS
SEE ALSO IMMUNOLOGY, HAPTENS
SEE ALSO IMMUNOPATHOLOGY. AUTOANTIGENS
SEE ALSO NEOPLASMS IMMUNOLOGY. TUMOR ANTIGENS
SEE ALSO TISSUE COMPATIBILITY-TRANSPLANT.
ISOALLOANTIGENS
SEE ALSO TOXINS
N01HB-62962-02 Red cell distributions in cyanate-treated
blood (human, sheep)
ROlHL-01803-23 0011 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Immunopathologic consequences of
cigarette smoking (human, rabbits, plants)
POlHL-06314-17 0067 Immunologic mechanisms in
cardiovascular disease - Mitogenic and antigenic activation
of lymphocyte sub-populations
POlHL-08805-15 0049 Regulation of ventilation and
pulmonary circulation - Pulmonary hypertension produced
by Dirofilaria immitis in the dog
** POlHL-11310-12 0099 Mechanisms of cardiovascular
disease - Carbohydrate chemistry of thy-1 and related
synaptosomal proteins
** P50HL-15389-07 0014 Pulmonary SCOR -Hypersensitivity
pneumonitis - Fractionation and characterization of pigeon
antigens
POlHL-15486-06 0002 Studies on thrombosis -
Characterization of antisera to fibrinopeptide B (human,
rabbits)
POlHL-15596-05 0001 Coagulation, fibrinolysis,
hemostasis and hepatitis - Defibrination (human)
POlHL-15596-05 0018 Coagulation, fibrinolysis,
hemostasis and hepatitis ■ Increased plasma lipids on
blood coagulation and thrombosis (human, animals)
POlHL-16748-05 0002 Cellular and immunological basis
of pulmonary diseases - Immunological function of alveolar
macrophages (rabbits, sheep, mice)
POlHL-16748-05 0006 Cellular and immunological basis
of pulmonary diseases - Sarcoidosis-Studies with bronchial
lavage (human)
ROlHL-17243-05 Cause of chronic experimental renal
hypertension (dogs, rabbits)
** P50HL-18828-03 0002 Specialized center of research in
thrombosis - Endothelial cell biology (human, guinea pig)
** ROlHL-19733-03 Absorption of antigen through inflamed
lungs (rabbits)
** R23HL-21730-01 vWagll -A new vWD deficient antigen
(human)
ROlHL-22924-01 The airway mucosal barrier (guinea pigs)
IMMUNOLOGY, ANTIGENS, SURFACE ANTIGENS
(GENERAL)
SEE ALSO BLOOD GROUPS ANTIGENS
SEE ALSO TISSUE COMPATIBILITY-TRANSPLANT,
ISOALLOANTIGENS
R01HL-08696-15 0012 Orthotopic heart transplantation -
Transplantation immunology -Modulation of donor
antigenicity (dogs)
(contd)
•Excludes routine methodology OR covers only general projects which preclude
"Onented significantly to above subject
indexing at the specific level
M Grant has subproieds describing specific research aspects.
See Appendix for investigator's name and grant number.
IMM
POlHL-15832-06 0002 Chemical-structural predispositions
to lung injury - Connective tissue in lung in development
and repair of injury (human, rats, mice)
P60HL1600806 0019 Wayne State University
comprehensive sickle cell center - Cell mediated immunity
in sickle cell anemia (human)
R01HL16711-05 RBC and endothelial membrane material
characteristics (human)
** P01HL1685104 0005 Human red cell membrane in
health and disease - Relation of hemoglobin species to
membrane properties (human)
P50HL-1 7648-04 0026 Study of ischemic heart disease ■
Control of muscle cell proliferation (organ culture)
POlHL-18576-03 OOU Thrombosis research program
project - Proteolysis and platelet function (human, cattle,
rabbits)
P01HL-18645-03 0003 Biology of the artery wall and
atherosclerosis - Synthesis of connective tissue proteins by
smooth muscle cells (human, monkeys)
P50HL-18828-03 0006 Specialized center of research in
thrombosis - Etiology and pathogenesis of atherosclerosis
(rabbit, monkey, rat, human)
ROlHL-19068-03 Changes in membrane properties during
erythropoiesis (chick embryo)
ROlHL-19234-03 Streptococci and heart -Cell-mediated
cross-reaction (mice)
R01HL-19419-03 Cellular interactions viith foreign
materials (mammals)
ROIHL-19741-03 Murine CRD-A model of chronic
pulmonary inflammation (mice, rats)
ROlHL-207 11-01 Structure-function relationships in red
cell NA-K pumps (goats)
IMMUNOLOGY, ANTIGENS BACTERIAL
SEE ALSO POLYSACCHARIDES, BACTERIAL (GENERAL)
ROlHL-03919-20 The cell suface of streptococci (rats,
human)
Immunologic mechanisms in
Antigens in cardiovascular disease
POlHL-0631417 0057
cardiovascular disease
(human)
POlHL-06314-17 0059
cardiovascular disease
Immunologic mechanisms in
Immunogenetic response to
streptococcal antigens in man
** POlHL-06314-17 0060 Immunologic mechanisms in
cardiovascular disease - Strept antigens and infections in
cardiovascular complications (human, animals)
R01HL13885-08 0006 Cystic fibrosis and pulmonary
disease ■ Cell mediated immunity and Pseudomonas
infections in cystic fibrosis (human)
ROlHL-13885-08 0008 Cystic fibrosis and pulmonary
disease ■ Pseudomonas specific activation of alveolar
macrophages (human, rabbits)
ROlHL-1512405 Genesis of hypertension in renal disease
(human, dogs)
P50HL-15389-07 0008 Pulmonary SCOR-Hypersensitivity
pneumonitis - Milwaukee patient study-Hypersensitivity
pneumonitis
** P50HL15389-07 0015 Pulmonary SCOR -Hypersensitivity
pneumonitis - Fractionation and characterization of
thermophilic Actinomycete antigens
P50HL-1538907 0017 Pulmonary SCOR-Hypersensitivity
pneumonitis ■ Immunology core (human)
P50HL15389-07 0019 Pulmonary SCOR-Hypersensitivity
pneumonitis - Microbiology core (human, animal)
POIHL-16387-04 0002 The blood vessel and
thrombogenesis - Hormonal effects on thrombogenesis
(rats, rabbits)
P01HL16769-05 0002 Pathobiologic and host defense
reactions in the lung - Pathogenesis of complement
dependent injury to the lungs (rabbits)
POlHL-16769-05 0008 Pathobiologic and host defense
reactions in the lung - Pulmonary immunocytologic defense
mechanisms against bacteria (human, animals)
** R01HL1756703 Lipoprotein-cytolytic toxin interaction
(Staphylococcus aureus, mammals, human)
ROlHL-19741-03 Murine CRD-A model of chronic
pulmonary inflammation (mice, rats)
ROlHL-19760-01 Cellular immune responses of the lung
(mice, guinea pigs)
ROlHL-20533-09 Pathogenesis of rheumatic fever (human,
rabbits)
ROlHL-2230101 Immunogenetics of chronic pulmonary
inflammation (mice)
lAAMUNOLOGY, ANTIGENS BACTERIAL,
BACTERIAL TOXINS (GENERAL)
SEE ALSO BLOOD TOXICOLOGY, BACTEREMIA-SEPTICEMIA
SEE ALSO IMMUNOLOGY, ANTIGENS BACTERIAL, ENDOTOXINS
SEE ALSO IMMUNOLOGY, ANTIGENS BACTERIAL, EXOTOXINS
SEE ALSO IMMUNOLOGY, ANTITOXINS
ROlHL-20652-01 Sites of leakage in pulmonary edema
(dogs)
IMMUNOLOGY, ANTIGENS BACTERIAL,
CHOLERA TOXIN
POlHL-06285-18 0186 Cardiovascular-respiratory
physiology and biochemistry Leukocyte hormone receptors
and cyclic nucleotides (tissue culture)
POlHL-0630818 0025 Mechanisms and therapy of
circulatory disease - Subcellular calcium pools in the
genesis of arrhythmias (dogs)
302
IMMUNOLOGY, ANTIGENS BACTERIAL,
DIPHTHERIA TOXIN
ROlHL-13636-08 Effects of pharmacologic agents on heart
metabolism (human, rodents)
IMMUNOLOGY, ANTIGENS BACTERIAL,
ENDOTOXINS
** R01HL01601-30 Blood coagulation and hemorrhagic
disease (horseshoe crabs)
ROlHL-08399-15 Platelet injury in infections and allergic
diseases (human)
P01HL08682-15 0019 Regulation of the cardiovascular
system ■ Hepatic immunophysiology and host-defense in
shock (rat, dog, human)
POlHL-08682-15 0021 Regulation of the cardiovascular
system - Hypoglycemia in pathogenesis of shock (dog)
ROlHL-14739-06 The role of leukocytes in thrombotic
disease (human, dogs)
POlHL-14985-07 0011 Adaptation to hypoxia -
Prostaglandins in the control of the pulmonary circulation
(animals)
ROlHL-16361-03 Fibrin complexes in intermediary
coagulation (human, rabbits)
** POlHL-164 11-04 0004 Blood systems in coagulation and
vessel disease - Platelets reactions in vascular injury
(human, animals)
** ROlHL-16646-05 Pathobiology of thromboembolic disorders
(human)
ROlHL-169 16-04 OOU The role of albumins in lung water
accumulation - Whole body distribution and exchange of
albumin (rabbits, human, monkeys)
ROlHL-17479-04 Blood storage-The production of
cardiotoxic material (dogs, human, swine)
M P01HL-1781204 Thrombosis and plasma proteins
P01HL-17812-04 0005 Thrombosis and plasma proteins -
In vitro systems of normal platelets, white cells, sera
(human)
** POlHL-17812-04 0007 Thrombosis and plasma proteins -
Blood components -Response to endotoxin (dogs, baboons)
POlHL-18576-03 0007 Thrombosis research program
project - Relationships between coagulability and
thrombosis (human, animals)
R01HL18731-02 RES stimulating materials in
experimental shock (dogs)
POlHL-18827-02 0001 Platelet vessel wall interactions in
thrombogenesis - Role of endothelial cells in the production
of thrombi (human, cattle)
** R01HL20878-02 Cellular aspects of lung Injury (rats.
rabbits)
ROlHL-21376-02 Blood-gas barrier solute and water
transport (rabbits)
ROlHL-21548-01 Pathogenesis of pulmonary
thromboembolic disease (human, mammals)
** ROlHL-23114-01
(dogs, rabbits)
ROlHL-23211-01
Control of platelet aggregation in shock
Active normoxic pulmonary vasodilatation
(rat. dog, sheep)
ROlHL-236 18-01 Substrate metabolism in isolated
myocytes in shock (dogs, rats, guinea pigs)
IMMUNOLOGY, ANTIGENS BACTERIAL,
EXOTOXINS
SEE ALSO IMMUNOLOGY. ANTIGENS BACTERIAL. DIPHTHERIA
TOXIN
SEE ALSO IMMUNOLOGY. ANTIGEf^S BACTERIAL,
STREPTOKINASE
SEE ALSO IMMUNOLOGY. ANTITOXINS
P01HL1613705 0001 Alveolar biology ■ Chemical
characterization of surfactant system-LlpId and lipid
protein fractions
IMMUNOLOGY, ANTIGENS BACTERIAL, M
PROTEIN
R0IHL01803-23 0001 Arteriosclerosis, glomerulonephritis.
rheumatic fever ■ Post-streptococcal glomerulonephritis
(rabbit)
ROlHL-01803-23 0018 Arteriosclerosis, glomerulonephritis.
rheumatic fever - Fetal immunization in pathogenesis of
glomerulonephritis in adult (rabbit)
ROlHL-039 19-20 The cell suface of streptococci (rats.
human)
** ROlHL-17194-03 Comparison of two inherited forms of
alpha-l-antitrypsin (human)
ROlHL-19307-03 Problems in prevention of rheumatic
heart disease (human)
IMMUNOLOGY, ANTIGENS BACTERIAL,
STREPTOKINASE
ROIHL 04366-19 Plasminogen-Activation and structure-
function relations (mammals, birds)
** ROlHL-11172-12 Physiology and biochemistiy of
fibrinolytic enzymes (human, animals)
ROlHL-13423-08 Structure-function studies of plasminogen
and plasmin (human)
P50HL-1421708 0049 Specialized center of research in
thrombosis - Fibrinolysis section -Clinical studies
P50HL-142 17-08 0052 Specialized center of research in
thrombosis - Radioisotope nuclear medicine section
(human, dog)
ROlHL-15817-06 Plasminogen activators from tissues
(human, pig, cattle)
" POlHL-1781204 0001 Thrombosis and plasma proteins •
Thrombosis and plasma proteins (cattle, guinea pigs)
IMM
ROlHL-18672-03 Dynamic studies of clot structure
formation (human)
IMMUNOLOGY, ANTIGENS FUNGAL
SEE ALSO TOXICOLOGY, MYCOTOXINS
P50HL-15389-07 0008 Pulmonary SCOR-Hypersensitivity
pneumonitis - Milwaukee patient study-Hypersensitivity
pneumonitis
P50HL 15389-07 0010 Pulmonary SCOR-Hypersensitivity
pneumonitis • Clinical study-Pulmonary lesions due to non-
invasive aspergillosis
P50HL-15389-07 0019 Pulmonary SCOR-Hypersensitivity
pneumonitis - Microbiology core (human, animal)
IMMUNOLOGY, ANTIGENS HELMINTHIC
P50HL19155-02 0004 Pathophysiology of pulmonary
edema Physical and chemical effects of multiple
pulmonary emboli (sheep)
P50HL19156-02 0004 Pulmonary SCOR-Chronic diseases
of airways - Interactions between mast cells, mediators
and nerves in canine asthma
lAAMUNOLOGY, ANTIGENS MICROBIAL,
ZYMOSAN
POlHL-1 1310-12 0096 Mechanisms of cardiovascular
disease - Complement chemistry and biology (human,
rabbits)
** P01HL15596-05 0012 Coagulation, fibrinolysis,
hemostasis and hepatitis - Platelet function -Phorbol ester
and zymosan-induced release activity
ROlHL-18731-02 RES stimulating materials in
experimental shock (dogs)
IMMUNOLOGY, ANTIGENS VIRAL
** POlHL-06314-17 0061 Immunologic mechanisms in
cardiovascular disease - Role of viruses in cardiovascular
and renal disease (human, mice)
ROlHL-18152-03 Vascular injury and atherosclerosis
(mice, coxsackievirus)
R01HL-19018-03 Etiologic factors in cryptogenic fibrosing
alveolitis (human)
P50HL-19171-02 0007 Pulmonaiy SCOR-Lung injury by
childhood infections - Immunologic studies in models of
lower respiratory tract infection (rodents)
ROlHL-2104701 Studies of coxsackievirus-induced
myocarditis in mice
ROlHL-23631-01 Immunogenetic factors in allergic
respiratory diseases (human)
lAAMUNOLOGY, ANTIGENS VIRAL, HEPATITIS B
ANTIGEN (HBAG)
NOlHB-62908-07 Maternal to infant transmission of
hepatitis 8 (human)
** POlHL-09011-15 0005 A research and resource program
in blood - Characterization of hepatitis-B antigen and the
cause of serum hepatitis (human)
•* P01HL09011-15 0018 A research and resource program
in blood - Hepatitis 6 in normal populations-Epidemiology,
risk factors and transmission
POlHL-1 1310-12 0095 Mechanisms of cardiovascular
disease ■ Blood and transfusion disorders (human, rats,
monkeys)
** POlHL-15596-05 0016 Coagulation, fibrinolysis.
hemostasis and hepatitis - Hepatitis-B antigen in whole
blood, plasma and plasma fractions (human, monkeys)
** P60HL-17269-04 0035 National heart and blood vessel
research and demonstration center - Blood resources-
Research program in viral hepatitis (human)
IMMUNOLOGY, ANTITOXINS
SEE ALSO IMMUNOLOGY, ANTIBODIES, IMMUNE SERA
ROlHL-18003-05 Digitalis-Mechanism and reversal studies
(dog, sheep, duck, guinea pig, human)
IMMUNOLOGY, COMPLEMENT
POlHL-06314-17 0047 Immunologic mechanisms in
cardiovascular disease - Role of intravascular coagulation
(human, animals)
P01HL06314-17 0062
cardiovascular disease
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
**OnerTteil significantly to above subject
Immunologic mechanisms in
Immunologic renal vascular
disease (human, animals)
P01HL06314-17 0063 Immunologic mechanisms in
cardiovascular disease - Glomerular cells in tissue culture
(human)
P01HL06314-17 0064 Immunologic mechanisms in
cardiovascular disease - Diabetic vascular disease (human,
rats, mice)
ROlHL-07652-14 Destruction of red blood cells in
hemolytic anemias (human, guinea pigs)
POlHL-0901115 0001 A research and resource program
in blood - Genetic markers of human blood and gene
mapping (human)
P01HL09011-15 0010 A research and resource program
in blood - Chromosome changes in human genetics
POlHL-1 1310-12 0096 Mechanisms of cardiovascular
disease - Complement chemistry and biology (human.
rabbits)
P01HL13108-09 0003 Clinical heart transplantation -
Endomyocardial biopsy pathology
ROlHL-13160-08 Human thrombin (also cattle)
P50HL-14136-07 0017 Pulmonary SCOR-Airways
obstructive diseases - Pediatric airways obstructive disease
(human)
(contd)
M Grant has subproiects describing specific research aspects.
See Appendix for investigator's name and grant number.
IMM
•• PbOHL 1S061 0? 0006 Response ol lung to injury
Compl«m«nl synthesis by pulmonary macropliages (guinea
pigs, human)
PWHl 15061 07 0007 Response ol lung to in)ury
Human factors loi phagocytosis in noimal and diseased
lungs
PMHL 15061 07 0009 Response ol lung to in)uni
Alveolar macrophages (human, rabbits)
P60HL 1516905 0009 Support toe center lor sickle cell
disease Infections in sickle cell anemia (human)
** ROIHL'1521506 Role ot complement in inttivascular
coagulation (rabbits, mice)
P50HL 1538907 0001 Pulmonary SCOR Hypersensitivity
pneumonitis Clinical studies ol hypersensitivity
pneumonitis
P50HL 15389-07 0008 Pulmonary SCOR Hypersensitivity
pneumonitis Milwaukee patient study Hypersensitivity
pneumonitis
P50HL 15389 07 0012 Pulmonary SCOR Hypersensitivity
pneumonitis Animal model-lmmunologic lung disease in
guinea pigs
P50HL 1538907 0017 Pulmonary SCOR Hypersensitivity
pneumonitis Immunology core (human)
** R01HL15690-07 Hydrolytic enzymes ot blood in health
and disease (human, animals)
P60H11599905 0008 Miami comprehensive sickle cell
center • Cyanate effect on host defense-Cellular and
humoral (human, guinea pig. rabbits)
** P60HL- 15999-05 0020 Miami comprehensive sickle cell
center - Deficiency in complement-dependent humoral
immunity -Sickle cell disease (human)
M POlHL-16411-04 Blood systems in coagulation and vessel
disease
** POlHL-16411-04 0001 Blood systems in coagulation and
vessel disease Molecular studies of the role of
complement in blood coagulation (human, rabbits)
POlHL-16411-04 0002 Blood systems in coagulation and
vessel disease ■ Early stages of coagulation and
cardiovascular disease (human, rabbits)
" POlHL-16411-04 0005 Blood systems in coagulation and
vessel disease - Chemical analysis of serum components
associated with coagulation (human, animal)
M POlHL-16769-05 Pathobiologic and host defense reactions
in the lung
** P01HL16769-05 0002 Pathobiologic and host defense
reactions in the lung - Pathogenesis of complement
dependent injury to the lungs (rabbits)
P60HL-17269-04 0033 National heart and blood vessel
research and demonstration center Autoallergic response
in cardiomyopathy, atherosclerosis, rheumatic heart disease
P01HL-178I2-04 0007 Thrombosis and plasma proteins -
Blood components-Response to endotoxin (dogs, baboons)
ROlHL-18012-04 Cellular defects in nocturnal
hemoglobinuria (human)
ROlHL-18625-03 Organization of arterial ground substance
(cattle)
POIHL- 1882 7-02 0006 Platelet vessel wall interactions in
thrombogenesis - Platelet immune injury in man
P50HL-18828-03 0001 Specialized center of research in
thrombosis - Membrane biology and hemostasis (human)
P50HL-18828-03 0003 Specialized center of research in
thrombosis - Structure and funct.on of plasma coagulation
inhibitors (human)
** P50HL-18828-03 0004 Specialized center of research in
thrombosis - Membrane changes in platelet physiology-Role
of complement (mice, human)
P5DHL-18828-03 0005 Specialized center of research in
thrombosis - Platelet inflammatory factors in thrombosis
(human, guinea pig)
P50HL-19157-02 0008 Studies in cystic fibrosis and
bronchiolitis - Serum proteins in cystic fibrosis (human)
ROlHL-19721-03 Lung inflammation-Lysosomal proteases
and liposomes (human, rabbits)
** ROlHL-19725-03 Complement induced pulmonary injury
(dogs, rabbits, sheep)
** ROlHL-19795-03 Synthesis of anaphylatoxic and
leucotactic peptides (human)
ROlHL-19819-03 Mitogen induced interstitial pneumonitis
(rabbits)
ROlHL-20063-03 Pathogenesis of pulmonary mycoplasma
infections (guinea pigs, mice)
** ROlHL-20220-03 Anaphylatoxins as inflammatory and
chemotactic agents (guinea pig. rabbit, human)
** ROlHL-20394-03 Complement activation by heart
subcellular membranes (human, dog)
ROlHL-20875-02 Chronic obstructive pulmonary disease-
Familial/genetic (human)
P60HL-20985-01 0002 Northern California sickle cell
center - Immunization with polyvalent pneumococcal
polysaccharide vaccine (human)
R23HL-21918-01 Hypersensitivity pneumonitis in guinea
pigs
** R23HL-2279901 Interaction of the complement and
coagulation systems (monkeys)
R23HL-22823-01 Phagocytic and immune defense
mechanisms of the lung (mice)
ROlHL-22996-01 Venom protcases-Action on plasma
protease inhibitors (human)
** ROlHL-23161-01 0005 Biology of myocardial ischemia -
Localization of complement in myocardial infarction (dog)
303
*• P60HL 23282 01 0002 Conipiohenbive hospildl/communily
sickle cell center Clinical evaluation of alternate
pathaway of compliment activation
ROIHI 23631 01 Immunogenetic factors in allergic
fcspiiatory diseases (human)
IMMUNOLOGY, COMPIEMENT, CHEMOTACTIC
FACTORS
POIHI 11310 12 0096 Mechanisms of cardiovascular
disease Complement chemistry and biology (human,
rabbits)
P50HL 14153 07 0014 tohns Hopkins Lung Center
Chionic diseases of airways Mediator release in asthma
(human)
P50HL 14217-08 0050 Specialized center o( research in
thrombosis Electron microscopy section (dogs)
POIHL 16411 04 0001 Blood systems in coagulation and
vessel disease Molecular studies of the role of
complement in blood coagulation (human, rabbits)
POIHL 1641104 0005 Blood systems in coagulation and
vessel disease Chemical analysis of serum components
associated with coagulation (human, animal)
POIHL 16748-05 0004 Cellular and immunological basis
of pulmonary diseases Cellular and immunological
processes in pulmonary defense systems
POlHL-16769-05 0002 Pathobiologic and host defense
reactions in the lung Pathogenesis of complement
dependent injury to the lungs (rabbits)
M POlHL-17382 05 Chemical mediators of acute pulmonary
disorders
POIHL 17382-05 0003 Chemical mediators of acute
pulmonary disorders - Chemical mediators relevant to
allergic reactions (human, guinea pigs)
P50HL-18828-03 0005 Specialized center of research in
thrombosis Platelet inflammatory factors in thrombosis
(human, guinea pig)
ROlHL-19628-03 Mechanisms of pulmonary alveolar
proteinoses (human, rats)
R01HL-19741-03 Murine CRD- A model of chronic
pulmonaiy inflammation (mice, rats)
** ROlHL-19806-03 Chemotactic control of airwiay phagocytes
(human, rabbits)
ROlHL-20002-03 Pulmonary complications of viral
infections (children)
** ROlHL-20220-03 Anaphylatoxins as inflammatory and
chemotactic agents (guinea pig. rabbit, human)
R23HL-21997-01 Pulmonary immunopathology in the
compromised host (guinea pigs)
ROlHL-22302-01 Immune responses in the human lung
(also rabbits, monkeys)
R23HL 22437-01 Leukotactic mediators in lung
inflammatory reactions (rats, rabbits, human)
ROlHL-23161-01 0005 Biology of myocardial ischemia -
Localization of complement in myocardial infarction (dog)
IMMUNOLOGY, COMPLEMENT ESTERASE
DEFICIENCY OR DYSFUNCTION
SEE METABOLIC DISORDERS INBORN, ANGIONEUROTIC
EDEMA (HEREDITARY)
IMMUNOLOGY, COMPLEMENT INHIBITORS
POlHL-1 13 10-12 0096 Mechanisms of cardiovascular
disease - Complement chemistry and biology (human,
rabbits)
P60HL-17265-04 0003 Community blood resource center
support - Research-Human factor IX-Role in intrinsic
clotting (also baboons, dogs)
P50HL- 188 28-03 0003 Specialized center of research in
thrombosis - Structure and function of plasma coagulation
inhibitors (human)
P50HL-18828-03 0004 Specialized center of research in
thrombosis - Membrane changes in platelet physiology-Role
of complement (mice, human)
P50HL-191 57-02 0008 Studies in cystic fibrosis and
bronchiolitis - Serum proteins in cystic fibrosis (human)
R23HL-22437-01 Leukotactic mediators in lung
inflammatory reactions (rats, rabbits, human)
ROlHL-23161-01 0005 Biology of myocardial ischemia -
Localization of complement in myocardial infarction (dog)
lAAMUNOLOGY, HAPTENS
SEE ALSO HYPERSENSITIVITY, ALLERGENS
ROlHL-14262-07 Leukocyte proteases and their lung
targets (human, dogs, rabbits)
POIHL-15832-06 0009 Chemical-structural predispositions
to lung injury - Immunology-Enzyme degradation products
of human lung elastin and microfibril
IMMUNOLOGY, HAPTENS (CARDIOLIPIN)
SEE PHOSPHOLIPIDS, PHOSPHOGLYCERIDES. CARDIOLIPINS
IMMUNOLOGY, lAAMUNE ADHERENCE
SEE ALSO IMMUNOLOGICAL TESTS AND IMMUNOASSAY,
IMMUNE ADHERENCE REACTION
P50HL-142 17-08 0050 Specialized center of research in
thrombosis - Electron microscopy section (dogs)
IMMUNOLOGY, IMMUNOREGULATORY ALPHA
GLOBULIN
ROlHL-197 77-03 Regulation of hypersensitivity in the lung
(rats, guinea pigs, rabbits, human)
IMM
IMMUNOLOGY, INTERFERON
P'jOHt 1421? 0/ 001') (.oriplaled iludies of pulmonary
fibrosis Pulmonaiy defense mechaniimj and fibrolit lung
disease (rodents, rabbits)
ROIHI 19651 03 Host (actors m pathogenesis ol
rcspiialory disease (human, hamsters)
IMMUNOLOGY, MICROBIAL
SEE ALSO IMMUNIIY. BACIfRICIDAl DEFff^SfS (GENERAL)
SEE ALSO IMMUNOLOGY. PROPERDIN
P50HL 19171 02 0012 Pulmonary SCOR Lung injury by
childhood infections Laboratory support core
ROIHL 19234 03 Streptococci and heart Cell mediated
cross reaction (mice)
ROIHL 19381 03 Pathogenesis of viral induced
atherosclerosis (human, chicken)
ROIHL 19741 03 Murine CRD A model of chronic
pulmonary inflammation (mice, rats)
ROIHL 19774 03 Pathogenesis of chronic lung disease
(rats, mice, bacterid/
ROIHL 20002 03 Pulmonary complications of viral
infections (children)
ROlHL-20063-03 Pathogenesis of pulmonary mycoplasma
infections (guinea pigs, mice)
ROlHL-20533-09 Pathogenesis of rheumatic fever (human,
rabbits)
ROlHL-22301-01 Immunogenetics of chronic pulmonary
inflammation (mice)
R23HL-22823 01 Phagocytic and immune defense
mechanisms of the lung (mice)
ROlHL-22981-17 Membrane-associated functions in
microorganisms (bacteria, protozoa)
IMMUNOLOGY, PROPERDIN
SEE ALSO IMMUNOLOGY, ANTIBODIES, IMMUNE SERA
SEE ALSO IMMUNOLOGY, ANTIBODIES, OPSONINS
POlHL-16411-04 0001 Blood systems in coagulation and
vessel disease - Molecular studies of the role of
complement in blood coagulation (human, rabbits)
P50HL-18828-03 0004 Specialized center of research in
thrombosis ■ Membrane changes in platelet physiology -Role
of complement (mice, human)
ROlHL-19721-03 Lung inflammation Lysosomal proteases
and liposomes (human, rabbits)
" R23HL-22799-01 Interaction of the complement and
coagulation systems (monkeys)
IMMUNOLOGY, SECRETORY (ANTIBODY)
(FACTOR) SYSTEM
P50HL 1415307 0016 Johns Hopkins Lung Center-
Chronic diseases of airways Airways defense mechanisms
(dogs)
P50HL-15061-07 0007 Response of lung to injury
Human factors for phagocytosis in normal and diseased
lungs
P50HL-15061-07 0009 Response of lung to injury -
Alveolar macrophages (human, rabbits)
P50HL-19171-02 0007 Pulmonary SCOR-Lung injury by
childhood infections - Immunologic studies in models of
lower respiratory tract infection (rodents)
P50HL-19171-02 0012 Pulmonary SCOR-Lung injuiy by
childhood infections - Laboratory support core
IMMUNOLOGY, SEROLOGY*
SEE ALSO BLOOD AND RE SYSTEM, BLOOD, SERUM
SEE ALSO IMIiflUNOLOGICAL TESTS AND IMMUNOASSAY,
HEMAGGLUTINATION*
SEE ALSO IMMUNOLOGICAL TESTS AND IMMUNOASSAY,
IMMUNODIFFUSION TESTS*
SEE ALSO MICROBIAL IDENTIFICATION AND CLASSIFICATION.
StROTYPING
** POlHL-09011-15 0001 A research and resource program
in blood - Genetic markers of human blood and gene
mapping (human)
POlHL-13 108-09 0009 Clinical heart transplantation - B
cell alloantigens in cardiac allograft compatibility (human)
POlHL-14388-07 9002 Regulation of the circulation in
pathological states - Core immunoassay laboratory (rabbits)
P60HL-23282-01 0004 Comprehensive hospital/community
sickle cell center - Bacterial, viral and mycoplasmal
infections and sickle cell disease complications
IMMUNOLOGY, TOXIC REACTIONS AND
MECHANISMS IN IMMUNOLOGY
SEE ALSO HYPERSENSITIVITY, TOXIC REACTIONS AND
MECHANISMS IN HYPERSENSITIVITY
P50HL-14212-07 0015 Correlated studies of pulmonary
fibrosis - Pulmonary defense mechanisms and fibrotic lung
disease (rodents, rabbits)
IMMUNOPATHOLOGY (GENERAL)
SEE ALSO BLOOD GROUP INCOMPATIBILITY
SEE ALSO HYPERSENSITIVITY (GENERAL)
SEE ALSO METABOLIC DISORDERS (INBORN), AMYLOIDOSIS
SEE ALSO NEOPLASMS IMMUNOLOGY
M ROlHL-01803-23 Arteriosclerosis, glomerulonephritis,
rheumatic fever
ROlHL-01803-23 0001 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Poststreptococcal glomerulonephritis
(rabbit)
ROlHL-01803-23 0005 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Immunologic and dietary synergy in the
pathogenesis of atherosclerosis (rabbits)
(contd)
•Excludes routine methodotogy OR covers only general projects which preclude
"Orieirted significantly to above subject
indexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
IMM
ROlHL-01803-23 0010 Arteriosclerosis, glomerulonephritis,
rheumatic fever ■ Atherosclerosis induction-Graft rejection
and hypercholesterolemia (rabbits)
" ROlHL-01803-23 0011 Arteriosclerosis, glomerulonephritis,
rheumatic fever • Immunopathologic consequences of
cigarette smoking (human, rabbits, plants)
** ROlHL-01803-23 0015 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Immunologic endothelial injury and lipid
diet atherosclerosis (rabbits, monkey)
ROlHL-01803-23 0020 Arteriosclerosis, glomerulonephritis.
rheumatic fever - Virus-induced arterosclerosis (chickens)
POlHL-03174-23 0002 Mechanisms of acute vascular
reaction to injury - Chemical structure, pathological
significance of amyloid substance (human, mice)
M POlHL-0631417 Immunologic mechanisms in
cardiovascular disease
** P50HL-1509207 0014 Immune and fibrotic response to
occupational environments - Clinical immunology core
resource
** R01HL15677-06 Autonomic nervous system function in
bronchial asthma (human, guinea pig, rabbit)
** ROlHL-16920-02 Proteases in normal and immunologically
injured lung (guinea pigs, rabbits)
** R01HL17404-05 Immunologic mechanisms in heart
disease (mice)
P01HL17813-04 0002 Lung disease and the oxygenation
of blood and tissue - Diffuse interstitial lung disease -
Ultrastructural abnormalities (human)
POlHL-17813-04 0008 Lung disease and the oxygenation
of blood and tissue - Pulmonary regulation of systemic
blood pressure (human, rabbits, rats)
** P01HL18827-02 0006 Platelet vessel wall interactions in
thrombogenesis - Platelet immune injury in man
** P50HL- 18828-03 0006 Specialized center of research in
thrombosis - Etiology and pathogenesis of atherosclerosis
(rabbit, monkey, rat, human)
** R01HL19628-03 Mechanisms of pulmonary alveolar
proteinoses (human, rats)
P01HL1971702 0019 Response of the lung to injury -
Animal model of fibrosing alveolitis (hamsters, guinea
pigs, rabbits)
R01HL19741-03 Murine CRD-A model of chronic
pulmonary inflammation (mice, rats)
ROlHL-20394-03 Complement activation by heart
subcellular membranes (human, dog)
ROlHL-21565-02 Pathogenesis of inflammatory lung injury
(rats, rabbits)
** ROlHL-22415-01 Mechanisms responsible for disease
severity in asthma (human)
IMMUNOPATHOLOGY, AUTOANTIBODIES
ROlHL-10036-13 Biology of red cell antigen-antibody
reaction (human)
R01HL1299409 The Rh complex of red cells (human)
P50HL-15092-07 0006 Immune and fibrotic response to
occupational environments - Immunologic studies in
silicosis (human, rabbits, hamsters, guinea pigs)
ROlHL-16246-06 Immunologic studies in
postpericardiotomy syndrome (human)
POlHL-16411-04 0003 Blood systems in coagulation and
vessel disease - Molecular events involving the late stages
of coagulation (rabbits)
POlHL-16411-04 0006 Blood systems in coagulation and
vessel disease - Factor Vll-lmmunochemistry and
immunobiology (human, mice)
ROlHL-16626-05 Studies of antibodies to antihemophilic
factors (human, rabbits)
P60HL-1 7265-04 0006 Community blood resource center
support • Research -Evaluation of platelet transfusions
(human, dog)
P60HL-1 7269-04 0033 National heart and blood vessel
research and demonstration center - Autoallergic response
in cardiomyopathy, atherosclerosis, rheumatic heart disease
ROlHL-19984-02 Blood pressure and immunogenetic
factors in the young (human)
ROlHL-20394-03 Complement activation by heart
subcellular membranes (human, dog)
" P60HL-20985-01 0007 Northern California sickle cell
center - Immunohematologic abnormalities in sickle cell
anemia (human)
R23HL-21328-02 The I blood group antigen of human
erythrocyte membrane
ROlHL-22671-01 Removal of senescent and stored human
red cells
ROlHL-2363101 Immunogenetic factors in allergic
respiratory diseases (human)
*• ROlHL-23654-01 Selected topics on blood transfusion
(rabbits, human)
IMMUNOPATHOLOGY, AUTOANTIGENS
** POlHL-0631417 0059 Immunologic mechanisms in
cardiovascular disease - Immunogenetic response to
streptococcal antigens in man
ROlHL-13629-08 Hemorrhagic diseases (human)
** P01HL-16769-05 0007 Pathobiologic and host defense
reactions in the lung - Immunogenetic factors in
sarcoidosis (human)
IMMUNOPATHOLOGY, AUTOIMMUNE
DISORDERS
SEE ALSO BLOOD AND RE DISORDERS, ANEMIA HEMOLYTIC
AUTOIMMUNE
304
Antigens related to graft rejection
R01HL01623-24
(rabbits, rats)
ROlHL-02751-21 Function and metabolism of serum
albumin (mammals, fish, amphibians)
P01HL-063 14-17 0048
cardiovascular disease
(rats, mice)
POlHL-06314-17 0062
cardiovascular disease
Immunologic mechanisms in
Pathogenesis of glomerulonephritis
Behavioral treatment of Raynaud's
Pulmonary and circulatory alterations
Selected topics on blood transfusion
Immunologic mechanisms in
Immunologic renal vascular
disease (human, animals)
ROlHL-07652-14 Destruction of red blood cells in
hemolytic anemias (human, guinea pigs)
** ROlHL-13336-09 Biochemistry and physiology of human
platelets
" ROlHL-13629-08 Hemorrhagic diseases (human)
ROlHL-13636-08 Effects of pharmacologic agents on heart
metabolism (human, rodents)
P50HL-15092-07 0006 Immune and fibrotic response to
occupational environments - Immunologic studies in
silicosis (human, rabbits, hamsters, guinea pigs)
** R01HL16603-05 Human and experimental renal diseases
(animals)
** ROlHL-16757-04 Autoimmune' thrombocytopenia (monkey)
" P60HL-1 7269-04 0033 National heart and blood vessel
research and demonstration center - Autoallergic response
in cardiomyopathy, atherosclerosis, rheumatic heart disease
R01HL190 18-03 Etiologic factors in cryptogenic fibrosing
alveolitis (human)
ROlHL-20140-02 Glycoproteins of platelet membrane and
platelet function (human)
ROlHL-20533-09 Pathogenesis of rheumatic fever (human.
rabbits)
POlHL-20984-02 0005 Cellular mechanisms in cardiac
hypertrophy - Neurohumoral receptors in cardiac growth
and compensatory hypertrophy (animals)
" ROlHL-22547-01
disease (human)
ROlHL-2258201
induced by IGE
ROlHL-236 54-01
(rabbits, human)
IMMUNOPATHOLOGY, CHEMOTHERAPY
SEE ALSO IMMUNITY, IMMUNOSUPPRESSIVE AGENTS
SEE ALSO IMMUNOPHARMACOLOGY
P01HL06312-17 0018 Surgical cardiology - Cardiac
transplantation growth (calves)
POlHL-06370-17 0001 Cardiopulmonary and renal
pathology research center - The humoral and cellular
mechanisms of allograft rejection (monkeys)
R01HL08696-15 0013 Orthotopic heart transplantation ■
Transplantation immunology-Cardiac heterotransplantation
(rabbits, dogs)
ROlHL-08696-15 0014 Orthotopic heart transplantation -
Transplantation immunology-Cardiac retransplantation
(dogs)
M POlHL-13 108-09 Clinical heart transplantation
** POlHL-1310809 0001 Clinical heart transplantation -
Therapy and prognosis (human)
POlHL-13108-09 0014 Clinical heart transplantation -
Platelets and coagulation in accelerated graft coronary
atherosclerosis
** POlHL-13108-09 0015 Clinical heart transplantation -
Antithymocyte globulin analysis and clinical effects
POIHL- 13 108-09 0016 Clinical heart transplantation -
Total lymphoid irradiation for immune response (dogs)
R01HL16219-05 Mechanisms of atherogenesis in chronic
uremia (human, rats)
POlHL-18646-03 0001 Studies basic to heart
transplantation - Individualized regulation of
immunosuppression (dogs, rats)
POlHL-18646-03 0002 Studies basic to heart
transplantation - Detection of rejection (dogs)
POlHL-18646-03 0009 Studies basic to heart
transplantation - Pathologic aspects of cardiac allograft
rejection (sheep, dogs)
ROlHL-18731-02 RES stimulating materials in
experimental shock (dogs)
IMMUNOPATHOLOGY, DIAGNOSIS*
** ROlHL-13885-08 0006 Cystic fibrosis and pulmonary
disease - Cell mediated immunity and Pseudomonas
infections in cystic fibrosis (human)
ROlHL-13885-08 0007 Cystic fibrosis and pulmonary
disease - Alveolar macrophage defense mechanism
(human, rabbits)
** ROlHL-13885-08 0008 Cystic fibrosis and pulmonary
disease - Pseudomonas specific activation of alveolar
macrophages (human, rabbits)
ROlHL-17993-04 0002 Ventricular dynamics from
surgically inserted markers ■ Left ventricle function in
human cardiac allograft
M POlHL-18646-03 Studies basic to heart transplantation
** POlHL-18646-03 0001 Studies basic to heart
transplantation - Individualized regulation of
immunosuppression (dogs, rats)
** POlHL-18646-03 0002 Studies basic to heart
transplantation - Detection of rejection (dogs)
POIHL-1864603 0003 Studies basic to heart
transplantation - Host responses to xenografts (rodents,
rabbits)
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
'•Oriented significantly to above subject.
IMM
** POlHL-18646-03 0004 Studies basic to heart
transplantation - Presensitization -Detection, incidence and
clinical significance
** POlHL-18646-03 0009 Studies basic to heart
transplantation - Pathologic aspects of cardiac allograft
rejection (sheep, dogs)
ROlHL-19018-03 Etiologic factors in cryptogenic fibrosing
alveolitis (human)
ROlHL-19651-03 Host factors in pathogenesis of
respiratoiy disease (human, hamsters)
** ROlHL-19721-03 Lung inflammation-Lysosomal proteases
and liposomes (human, rabbits)
** R0IHL-19725-03 Complement induced pulmonary injury
(dogs, rabbits, sheep)
ROlHL-19819-03 Mitogen induced interstitial pneumonitis
(rabbits)
ROlHL-20002-03 Pulmonary complications of viral
infections (children)
ROlHL-20063-03 Pathogenesis of pulmonary mycoplasma
infections (guinea pigs, mice)
IMMUNOPATHOLOGY, lAAMUNE COMPLEX
DISEASES (SEE ALSO SPECIFICS)
SEE ALSO IMMUNOPATHOLOGY. AUTOIMMUNE DISORDERS
** R01HL01803-23 0005 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Immunologic and dietary synergy in the
pathogenesis of atherosclerosis (rabbits)
** ROlHL-10980-11 Ultrastructural renal pathology (human,
rats)
POlHL-11310-12 0096 Mechanisms of cardiovascular
disease - Complement chemistry and biology (human,
rabbits)
P50HL-15389-07 0001 Pulmonary SCOR-Hypersensitivity
pneumonitis - Clinical studies of hypersensitivity
pneumonitis
P50HL-15389-07 0008 Pulmonary SCOR-Hypersensitivity
pneumonitis - Milwaukee patient study-Hypersensitivity
pneumonitis
P50HL-1538907 0011 Pulmonary SCOR-Hypersensitivity
pneumonitis - Animal model -Hypersensitivity pneumonitis
in rabbits
** P50HL-15389-07 0012 Pulmonary SCOR-Hypersensitivity
pneumonitis - Animal model-lmmunologic lung disease in
guinea pigs
P50HL-15389-07 0017 Pulmonary SCOR-Hypersensitivity
pneumonitis - Immunology core (human)
** ROlHL-16757-04 'Autoimmune' thrombocytopenia (monkey)
P60HL-172e9-04 0033 National heart and blood vessel
research and demonstration center - Autoallergic response
in cardiomyopathy, atherosclerosis, rheumatic heart disease
ROlHL-19018-03 Etiologic factors in cryptogenic fibrosing
alveolitis (human)
ROlHL-20095-03 Role of lymphokines and monocytes in
lung fibrosis (human, guinea pigs, rats)
** R23HL-21918-01 Hypersensitivity pneumonitis in guinea
pigs
** R23HL-22437-01 Leukotactic mediators in lung
inflammatory reactions (rats, rabbits, human)
IMMUNOPATHOLOGY, IMMUNOLOGIC
DEFICIENCY DISORDERS
SEE ALSO BLOOD AND RE DISORDERS, LEUKOCYTE
DISORDERS, PHAGOCYTE DYSFUNCTION
(GENERAL)
SEE ALSO IMMUNITY. IMMUNOLOGICAL UNRESPONSIVENESS
SEE ALSO METABOLIC DISORDERS INBORN. ANGIONEUROTIC
EDEMA (HEREDITARY)
SEE ALSO METABOLIC DISORDERS INBORN, CHEDIAK-HIGASHI
SYNDROME
POlHL-06314-17 0067 Immunologic mechanisms in
cardiovascular disease - Mitogenic and antigenic activation
of lymphocyte sub-populations
ROlHL-09902-13 Comparative study of coagulation and
vascular disease (animals)
ROlHL-1283309 Genetic and environmental influences on
lung disease (human)
** P50HL-15092-07 0008 Immune and fibrotic response to
occupational environments - Animal models of asbestosis
(hamsters)
** P60HL-15160-07 0014 Center for sickle cell disease -
Replacement therapy of opsonin deficiency in sickle cell
anemia (children)
P60HL-16005-05 0020 Comprehensive sickle cell center -
Studies of the immunologic defect in sickle cell anemia
(human)
** P60HL-17265-04 0008 Community blood resource center
support • Research-Blood genetic markers as biological
probes (human)
P50HL-19171-02 0003 Pulmonary SCOR-Lung injury by
childhood infections - Natural history, host defense defects-
Children with chronic pulmonary disease
** P60HL-23282-01 0002 Comprehensive hospital/community
sickle cell center - Clinical evaluation of alternate
pathaway of compliment activation
IMMUNOPHARMACOLOGY
SEE ALSO IMMUNOPATHOLOGY, CHEMOTHERAPY
POlHL-06285-18 0186 Cardiovascular-respiratory
physiology and biochemistry - Leukocyte hormone receptors
and cyclic nucleotides (tissue culture)
POlHL-06370-17 0004 Cardiopulmonary and renal
pathology research center - Lymphocytes in graft rejection
and immune surveillance (human)
(contd)
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
IMM
R01HL08696 15 0012 Orthotopic he«tt ttansplantalion
Tfinsplintatlon immunolojy Modulation ot donor
antigenicitY (dogs)
•• ROIHI 18003 05 Oijitahs Mechanism and reversal studies
(dog. sheep, duch. guinea pig. human)
•• ROIHL 19062 03 Pharmacologic control ol mast cell
phosphodiesterase (human, lats)
ROIHI 19721 03 lung mtlammation-lysosomal proteases
and liposomes (human, lahbits)
ROIHI 19777 03 Regulation ol hypersensitivity in the lung
(rats, guinea pigs, rabbits, human)
ROIHL 1981903 Mitogen induced interstitial pneumonitis
(rabbits)
R23HL 21089 02 Localization of mediators in dispersed
lung cells (guinea pigs, human)
ROIHL 2208? 02 Humoral mediators of pulmonary
inflammation (guinea pigs)
lAAMUNOREGULATORY ALPHA GLOBULIN
SEE IMMUNOLOGY, IMMUNOREGULATORY ALPHA GLOBULIN
IMMUNOSUPPRESSION
SEE IMMUNITY. IMMUNOSUPPRESSION
IMMUNOSUPPRESSIVE AGENTS
SEE IMMUNITY. IMMUNOSUPPRESSIVE AGENTS
lAAMUNOSYMPATHECTOMY
SEE NEUROSURGERY. SYMPATHECTOMY.
IMMUNOSYMPATHECTOMY
IMMUNOTHERAPY
SEE IMMUNITY. IMMUNIZATION (IMMUNOTHERAPY)
IMP:PYROPHOSPHATE
PHOSPHOR1BOSYLTRANSFERASE
SEE GLYCOSYLTRANSFERASES. IMPPYROPHOSPHATE
PHOSPHORIBOSYLTRANSFERASE
IMPEDANCE, ELECTRICAL
SEE ELECTRICAL IMPEDANCE
IMPEDANCE, FLUID FLOW
SEE PHYSICAL PROPERTIES, FLUID FLOW IMPEDANCE
IMPLANT COMPATIBIUTY
SEE TISSUE COMPATIBILITY-TRANSPLANT. IMPLANT
COMPATIBILITY
IMPLANTS
SEE TISSUE COMPATIBILITY-TRANSPLANT. IMPLANT
INAPPROPRIATE ANTIDIURETIC HORMONE
SYNDROME
SEE METABOLIC DISORDERS (INBORN). DIABETES INSIPIDUS
INBORN ERRORS OF METABOLISM
SEE METABOLIC DISORDERS INBORN
INBREEDING
SEE GENETICS, POPULATION GENETICS. INBREEDING
INCLUSION BODIES
SEE CELL INCLUSION BODIES
INCOME INSURANCE
SEE SOCIOECONOMICS. FINANCING ORGANIZED. INCOME
INSURANCE
INDERAL
SEE NAPHTHYUMINES, PROPRANOLOL
INDEPENDENCY, EMOTIONAL
SEE PSYCHOLOGY, EMOTIONAL DEPENDENCY-INDEPENDENCY
INDEXING
SEE INFORMATION SYSTEMS, INDEXING
INDIANS, AMERICAN
SEE SOCIAL GROUPS, ETHNIC, AMERICAN INDIANS
INDICATOR DILUTION (CONCENTRATION)
TECHNIQUES, CARDIOVASCULAR
SEE CARDIOVASCULAR DISORDERS DIAGNOSIS, INDICATOR
DILUTION (CONCENTRATION)*
INDICATORS AND REAGENTS
SEE ALSO CARDIOVASCULAR DISORDERS DIAGNOSIS,
INDICATOR DILUTION (CONCENTRATION)*
SEE ALSO DYES
SEE ALSO RADIOTRACER*
** P01HL-16683-04 0006 Function and growth of cardiac
and skeletal muscle - Chemical studies of the contractile
system-Development of new reagents
POlHL-17813-04 0007 Lung disease and the oxygenation
of blood and tissue Studies on the function of myoglobin
(dogs)
ROlHL-18249-04 Isolation and identification of platelet
membrane (human)
P50HL-19153-02 0005 SCOR-Pulmonary edemas-Eitology,
pathogenesis - Lung vascular permeability measured by
indicator dilution methods (sheep)
INDIUM RADIOISOTOPES (1 1 1,1 13M)
SEE RADIOISOTOPES, INDIUM
INDIVIDUALITY
SEE PSYCHOLOGY, PERSONALITY
305
INDOCIN
SEE BEN70PYRR0LI CARBOXYIIC ACIDS. INOOMETHACIN
INDOCYANINE GREEN
Sfl BfN/OPYRROirS. INDOCYANINE GREEN
INDOLEAMINES
Sff BEN70PYRR0LES. INDOLEAMINES (GENERAL)
INDOLES
SEE BENZOPYRROLES. INDOLES (SEE ALSO APPROPRIATE
SPECIFICS UNDER BENZOPYRROLES)
INDOMETHACIN
SEE BENZOPYRROLE CARBOXYLIC ACIDS, INOOMETHACIN
INDUCERS
SEE GENETICS. GENETIC REGULATION. GENETIC INDUCTION
REPRESSION DEREPRESSION. INDUCERS
INDUSTRIAL HAZARD
SEE OCCUPATIONAL HEALTH, OCCUPATIONAL HAZARDS
INDUSTRIAL HEALTH
SEE OCCUPATIONAL HEALTH
INDUSTRIAL MEDICINE
SEE OCCUPATIONAL HEALTH, INDUSTRIAL MEDICINE
INDUSTRIAL WORKERS
SEE OCCUPATIONS. INDUSTRY
INDUSTRY (OCCUPATIONS)
SEE OCCUPATIONS. INDUSTRY
INERT GAS NARCOSIS
SEE INJURIES. DYSBARISM. INERT GAS NARCOSIS
INERT GASES
SEE GAS ELEMENTS. INERT
INFANT AND MATERNAL CARE
SEE HEALTH CARE SERVICES. MATERNAL AND INFANT CARE
INFANT DIABETES
SEE CARBOHYDRATES METABOLISM DISORDERS, DIABETES,
JUVENILE
INFANT HUMAN
SEE CHILDREN, INFANT (BIRTH TO 1 YR)
INFANT MENTAL DEVELOPMENT
SEE CHILD MENTAL DEVELOPMENT
INFANT MORTALITY
SEE CHILDREN, INFANT AND CHILD MORTALITY
INFANT MORTALITY (ANIMAL)
SEE AGE (ANIMAL). INFANTS MORTALITY
INFANT NEWBORN
SEE CHILDREN, INFANT NEWBORN (BIRTH TO 4-6 WKS)
INFANT NEWBORN (ANIMAL)
SEE AGE (ANIMAL). INFANTS NEWBORN
INFANTS OF HIGHER VERTEBRATES
SEE AGE (ANIMAL). INFANTS
INFARCT LIMITING AGENTS, HEART
SEE CARDIOVASCUUR AGENTS, CARDIOTONIC AND
CARDIOPROTECTIVE DRUGS (GENERAL)
INFARCTION
SEE CARDIOVASCULAR DISORDERS, INFARCTION
INFECTION MECHANISM
SEE VIRUS DISEASE CHARACTERISTICS, INFECTION
MECHANISMS (GENERAL)
INFECTION OF SURGICAL WOUNDS
SEE INJURIES, SURGICAL WOUND INFECTION
INFECTIONS, SECOtJDARY
SEE COMMUNICABLE DISEASES, INFECTIONS, SECONDARY
INFECTIONS AND CANCER, COMPLICATIONS
SEE NEOPLASMS, CANCER COMPLICATIONS OF, INFECTIONS
INFECTIOUS DISEASES (GENERAL)
SEE COMMUNICABLE DISEASES (GENERAL)
INFECTIOUS DISEASES CONTROL
SEE COMMUNICABLE DISEASE CONTROL
INFECTIOUS HEPATITIS
SEE LIVER DISORDERS, HEPATITIS VIRAL HUMAN
INFLAMMATION
SEE DISEASES, PATHOLOGIC PROCESSES, INFLAMMATION
INFLUENZA
SEE VIRUS DISEASES, MYXOVIRUS, INFLUENZA
INFLUENZA VIRUSES
SEE VIRUSES, MYXOVIRUSES, INFLUENZA VIRUSES
INFORMATION AND COMMUNICATION
(GENERAL)
SEE ALSO BIOMEDICAL SYSTEMS AUTOMATED, MAGNETIC
RECORDING SYSTEMS
INF
SEE ALSO BIOMEOICAl SYSTEMS AUIOMAItD, MONIIORING
DEVICES
SEE ALSO BIOMEOICAl SYSTEMS AUTOMATED, lElEMfDICINE
(GENE RAD
SEE ALSO COMPUTER (GENERAL) INCl COMPUIfR DAI*
PROCESSING (GFNERAl)
SEE ALSO EDUCATION, AUOIOVISUAl AND OIHfR IRAININO
AIDS
SEE ALSO EDUCATION. COMPUTER ASSISTED INSTRUCTION
SEE ALSO EDUCATION. PROGRAMMED INSTRUCTION,
TEACHING MACHINES
SEE ALSO OPTICS. PHOTOGRAPHY, CINEMATOGRAPHY*
NOIHV 72983 00 Nutrition counseling in hyperlipidemia
INFORMATION AND COMMUNICATION,
AUTOMATIC DATA PROCESSING
SEE ALSO BIOMEDICAL SYSTEMS AUTOMATED
SEE ALSO COMPUTER (GENERAL) INCl COMPUTER DATA
PROCESSING (GENERAL)
SEE ALSO INFORMATION SYSTEMS. INFORMATION RETRIEVAL
SEE ALSO OPTICS, IMAGE PROCESSING ANALYSIS AND
DISPLAY*
R01HL-14645-07 Blood flow measurement by ultrasonic
catheter tip methods (human, dogs)
P50HL 17648-04 0032 Study ol ischemic heart disease -
Data management- Statistics and data files
POlHL-18208 04 0002 Center for the study of blood cell
rheology Holography of RBC shape (human)
ROlHL-18968-03 Computer technology for transanlal
tomography
NOlHV-32973 12 Coordinating center for collaborative
studies on coronary artery surgery
INFORMATION AND COMMUNICATION,
CLASSIFICATION (GENERAL)
SEE ALSO BIOLOGY. SYSTEMATIC
SEE ALSO BLOOD GROUPS
SEE ALSO CELL TYPES
SEE ALSO DISEASE CLASSIFICATION
SEE ALSO MICROBIAL IDENTIFICATION AND CLASSIFICATION
aECHNIQUES)
SEE ALSO NEOPLASMS CUSSIFICATION AND STAGING
SEE ALSO TISSUE COMPATIBILITY TRANSPLANT.
HISTOCOMPATIBILITY TYPING
** R01HL-18850-03 Classification code for Frank orthogonal
ECG
INFORMATION AND COMMUNICATION,
NOMENCLATURE
ROlHL-10582-12 Thrombosis and hemostasis -Analysis,
methods and standards (human, cattle, venom)
INFORMATION AND COMMUNICATION,
SYSTEMS ANALYSIS
SEE ALSO MODELS, MATHEMATICAL
** R01HL-14529-07 Systems analysis of baroreflex (dogs)
** ROlHL-15659-05 Dynamic isolation studies of control of
respiration (human)
P60HL-1729204 0008 Vermont Lung Center - Respiratory
physiology-Teaching, learning and auditing problem-solving
skills
P50HL-17648-04 0032 Study of Ischemic heart disease -
Data management-Statistics and data files
INFORMATION AND COMMUNICATION,
SYSTEMS ANALYSIS, OPERATIONS RESEARCH
** POlHL-09011-15 0017 A research and resource program
in blood Operations research laboratory
INFORMATION BANKS
SEE INFORMATION SYSTEMS (INCL BANKS AND CENTERS)
INFORAAATION CENTERS
SEE INFORMATION SYSTEMS (INCL BANKS AND CENTERS)
INFORMATION-COMMUNICATION BEHAVIOR,
LANGUAGE DEVELOPMENT
P50HL-19187-02 0007 Pediatric pulmonary SCOR-Hyaline
membrane disease - Follow-up study-Infants with hyaline
membrane disease (human)
INFORMATION DISSEMINATION
SEE ALSO EDUCATION, AUOIOVISUAL AND OTHER TRAINING
AIDS
SEE ALSO HEALTH RECORDS
SEE ALSO INFORMATION SYSTEMS (INCL BANKS AND
CENTERS)
SEE ALSO PUBLICATIONS
NOlHB-62963-03 International bone marrow transplant
registry
NOlHB-62964-03 International bone marrow transplant
registry
R01HL-12715-10 Dynamic cardiovascular measurement
using ultrasound
** P60HL-15157-07 0003 Comprehensive center for sickle
cell disease - Public education
P60HL-15158-07 0027 Comprehensive sickle cell center -
Community advisory board-Nancy Cobb house
P60HL-15158-07 0028 Comprehensive sickle cell center -
Education
P60HL-15160-07 0003 Center for sickle cell disease ■
Genetic counseling In hemogloblnopathles-Dimensions,
effectiveness
(contd)
•Excludes routine methodotogy OR covers only general projects which preclude
**Oriented significantly to above subject.
indexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
INF
306
INF
P60HL-15160-07 0017 Center for sickle cell disease -
Demonstration-Education, screening, counseling, patient
care
P60HL-15169-05 0021 Support for center for sickle cell
disease ■ Multidisciplinary module system for education,
screening and counseling
** P60HL- 15996-06 0006 Cincinnati comprehensive sickle
ceil center - Education
P6OHL-1S999-05 0004 Miami comprehensive sickle cell
center ■ Education, screening and counseling
P6OHL-1600S-0S 0001 Comprehensive sickle cell center -
Demonstration-Community service component
P60HL-16008-06 0011 Wayne State University
comprehensive sickle cell center - Education, screening and
counseling
** P60HL-17269-04 0036 National heart and blood vessel
research and demonstration center - Public education
P60HL-1 7269-04 0043 National heart and blood vessel
research and demonstration center - Dietary modification -
Effect on cardiovascular risk parameters (human)
P60HL-1 7292-04 0018 Vermont Lung Center Group
patient education-Breathing workshop project
ROlHL-22380-01 Detroit hypertension control program
INFORMATION DISSEMINATION, MASS MEDIA
P60HL- 15996-06 0006 Cincinnati comprehensive sickle
cell center - Education
P60HL- 17269-04 0036 National heart and blood vessel
research and demonstration center - Public education
•* P60HL-17292-04 0020 Vermont Lung Center - Mass
information -Education project
** R18HL-21906-01 Stanford five city multifactor risk
reduction study
INFORMATION DISSEMINATION, MEETINGS
CONFERENCES SYMPOSIA
ROlHL-13881-08 The American Red Cross National
Fractionation Center
P60HL-1S170-05 0003 Support for center for sickle cell
anemia - Adult services -Educational programs
** R13HL-22159-01 Conference on non-ventilatory functions
of the lungs (New Hampshire)
INFORMATION DISSEMINATION, MEETINGS
CONFERENCES SYMPOSIA, INTERNATIONAL
** R13HL-20765-01 Eleventh Princeton Conference on
Cerebrovascular Disease (new Jersey)
** R13HL-22068-01 Conference on 'The Internal Environment'
(California)
** R13HL-22525-01 International symposium on the
diaphragm (Virginia)
** R13HL-23072-O1 Gordon Research Conference-Cardiac and
skeletal muscle (New Hampshire)
INFORMATION DISSEMINATION, MEETINGS
CONFERENCES SYMPOSIA, WORKSHOP
SEE ALSO EDUCATION. TRAINING
P60HL-1729204 0018 Vermont Lung Center - Group
patient education-Breathing workshop project
NOlHV-62969-03 Cardiology patient simulator evaluation
** NOlHV-72983-00 Nutrition counseling in hyperlipidemia
INFORMATION EXCHANGE
SEE INFORMATION SYSTEMS (INCL BANKS AND CENTERS)
INFORAAATION GATHERING (DATA
COLLECTION)
SEE ALSO HEALTH RECORDS, CASE HISTORY
SEE ALSO POPUUTION SURVEYS
NOlHB-62963-03 International bone marrow transplant
registry
NOlHB-62964-03 International bone marrow transplant
registry
** NOlHB-62968-07 National blood banking data needs
R01HL1437807 Lipemlas and reconstructive cardiac
surgery (human)
P60HL-172e904 0043 National heart and blood vessel
research and demonstration center - Dietary modification-
Effect on cardiovascular risk parameters (human)
R25HL-18414-03 Hypertension-Family strategies for
patient adherence
NOlHV-22917-11 Lipid research clinic (human)
NOIHV-53006-06 Evaluation of model VII left ventricular
assist device (human)
NOlHV-53027-05 Data coordinating center for the unstable
angina pectoris study
** HOlHV-62955-04 Data collection In clinical pathology and
morbid anatomy (men)
NOlHV-62957-05 Coordinating center model for NHLI
clinical trials
NOlHV-72915-02
population
NOlHV-72984-03
(human)
NOlHV-72986-02
(human)
NOlHV-72987-02
(human)
NOlHV-72989-02
(human)
NOIHV-72990-00
(human)
Therapy for hypertension in the general
High blood pressure control procam
High blood pressure control program
High blood pressure control program
High blood pressure control program
High blood pressure control program
INFORMATION GATHERING (DATA
COLLECTION), QUESTIONNAIRES
R01HL-164610S Late results of valve replacement -
Computer analysis (human)
ROlHL-187 15-02 Hypertension incidence project (human)
P5DHL-19171-02 0005 Pulmonary SCOR -Lung injury by
childhood infections - Chronic respiratory disease of
children in North Carolina
R01HL-20e62-02 Physical activity, fitness and
epidemiology of CHD
ROlHL-22528-02 Early risk predictors for chronic
pulmonary disease (human)
NOlHR-32900-09 Pilot study to standardize the
measurement of 'closing volume' (human)
NOlHV-53010-03 NAS-NRC twin registry
INFORMATION GATHERING METHODS
EVALUATION-STANDARDS
ROIHL 15790-06 Follow-up study of acute coronary heart
attacks (human)
P60HL-17292-04 0023 Vermont Lung Center - Health
information resources
P50HL-191 71-02 0005 Pulmonary SCOR-Lung injury by
childhood infections - Chronic respiratory disease of
children in North Carolina
ROlHL-20637-02 Recovery after heart surgery-Bio-
behavioral factors (human)
ROlHL-21352-02 Community studies of obstructive lung
disease (human)
INFORMATION PROCESSING AND CONTROL
(BIOLOGICAL)
SEE ALSO ENDOCRINOLOGY, HORMONAL REGUUTION AND
CONTROL (MECHANISMS)
SEE ALSO ENZYME FEEDBACK
SEE ALSO GENETICS, GENETIC CODING
SEE ALSO GENETICS, GENETIC REGULATION
SEE ALSO INFORMATION PROCESSING AND CONTROL
(NEURAL)
SEE ALSO SENSORY FEEDBACK
ROlHL-05062-18 Lipid metabolism in cultured cells
(human, rats, rabbits)
R01HL-08634-15 Enzymic cholesterol synthesis (human,
rats, protozoa, yeast)
ROlHL-09544-12 Biochemistry of contractile proteins
(animals)
" POlHL-11310-12 0105 Mechanisms of cardiovascular
disease - Biosynthesis of mammalian glycoproteins
(rabbits)
Nutritional regulation of enzyme activity
ROlHL-14092-07 Homeostatic regulation of plasma choline
(rats, dogs, chickens)
Uptake and metabolism of lipids by the
ROlHL-12138-08
(rats, human)
ROlHL-13302-09
liver (rats)
ROlHL-13929-06 Single nephron response to chronic
obstruction (frogs, rats)
ROlHL-15390-12 Regulation of blood flow in the
Effectors of cholesterol synthesis (rats)
Contraction In heart and other striated
microcirculation
ROlHL-16294-04
ROlHL-16606-11
muscles (frogs)
ROlHL-17372-03 Adenine nucleotide maintenance In the
Ischemic heart (rats)
ROlHL-17882-04 Regulation of HMG-COA reductase and
sterol synthesis (human, mammals)
ROlHL-18426-04 Regulation of renal hemodynamics (dogs)
ROlHL-18554-03 Taurine metabolism in mammalian heart
(rodents, cattle, swine)
** ROIHL- 192 82-03 Regulation of the activation of human
factor X
ROlHL-20464-01 Regulation of cardiac and skeletal
muscle contraction (mammals)
ROlHL-20859-02 Beta adrenergic catecholamine receptor
** ROlHL-20905-02 Synthesis of fetal hemoglobin in erythrold
cells (sheep, human)
** R23HL-21488-01 Myosln-llnked regulation In vertebrate
smooth muscle (calf aorta)
** R23HL-21990-01 Accuracy of the ventilatory response to
exercise (dogs)
ROlHL-221 94-02 Allosteric function of platelet contractile
proteins (human)
ROlHL-22239-01 The molecular basis of electrical
excitability (chick embryos, rats)
ROlHL-228 12-01 Regulation of hepatic production of HDL
(rats)
ROlHL-236 15-01 Biochemistry of contractile proteins
(chicken, rabbit)
INFORMATION PROCESSING AND CONTROL
(BIOLOGICAL), HOMEOSTASIS
SEE ALSO BODY FLUID BALANCE, ACID-BASE
SEE ALSO BODY FLUID BALANCE. IONIC
SEE ALSO CELL GROWTH REGULATION
SEE ALSO TEMPERATURE (BODY) REGUUTION
ROlHL-07723-15 Reflex control of vascular capacitance in
shock
** POlHL-11678-11 0040 Cardiovascular dynamics and their
control - Control of plasma potassium concentration (dogs)
ROlHL-13427-09 Neural control of blood volume (monkeys,
dogs)
** R01HL-13901-08 Ontogeny, ultrastructure, function in
lymphatic system (birds, fish, mammals)
POlHL-14388-07 0153
pathological states -
(rats)
POlHL-14388-07 0183
pathological states
Regulation of the circulation in
Subcellular distribution of calcium
Cellular basis of cardiac contractility
Cardiopulmonary control coupling in
Regulation of the circulation in
Vasopressin in cardiovascular
regulation (dogs, rats)
ROlHL-1452907 Systems analysis of baroreflex (dogs)
ROlHL-14967-06 Chemoreceptor function in dynamic
ventilatory control (human, dogs)
ROlHL-15124-05 Genesis of hypertension in renal disease
(human, dogs)
ROlHL-15607-06 Physiological control of splanchnic
circulation (dogs)
ROlHL-16010-16
(frogs)
•* ROlHL-16390-05
exercise (dogs)
** ROlHL-16714-05 Endothelial cell communication in
homeostasis (human, mammals)
ROlHL-18351-03 Brain metabolism, acid-base balance,
and respiration
ROlHL-18579-03 Vasoactive hormones and blood pressure
regulation (dogs, rats, rabbits)
** POlHL-18708-03 0005 Oxygen, energy and contractility in
cardiac tissue - Cytosolic calcium homeostasis and
bioenergetlcs of cardiac tissue (animals)
ROIHL- 18882-02 Hormones in hypertension (human)
ROlHL-19455-03 Role of endothelial cells in vascular
permeability (tissue culture)
R23HL-19601-01 Cardiac response to chronic metabolic
acidosis (rats)
ROlHL-20054-02 Cultured blood vessel cells -
Pathophysiology (human, animals)
ROlHL-2 1120-02 Membrane dynamics in alveolar
macrophages (rabbits)
** ROlHL-21272-02 Sodium homeostasis and renal
prostaglandins (dogs)
** ROlHL-2153202 Cardiovascular homeostasis and learning
(frogs, rats, human)
ROlHL-22069-02 Experimental renal arterial hypertension
(dogs)
** ROlHL-22873-01 Adrenoceptor Interconversion and
hormone homeostasis
INFORAAATION PROCESSING AND CONTROL
(NEURAL)
SEE ALSO NEUROPHYSIOLOGY (GENERAL)
SEE ALSO PSYCHOBIOLOGY, PSYCHOPHYSIOLOGY
SEE ALSO SENSORY FEEDBACK
ROlHL-05883-18 0007
capacitance vessels
blood flow (dogs)
ROlHL-05883-18 0008
capacitance vessels
Reflex control of resistance and
Prostaglandins and skeletal muscle
Reflex control of resistance and
Oxygen consumption of the
chronically denervated dog heart
POlHL-06285-18 0180 Cardiovascular-respiratory
physiology and biochemistry - Vagal C-flbers and their
influence on visceral and somatic function (animals)
POlHL-06285-18 0208 Cardiovascular-respiratory
physiology and biochemistry - Composition, properties and
turnover of pulmonary surfactant (human, animals)
POlHL-06835-17 0044 Cardiovascular disease -
Baroreceptors In control of blood pressure during sleep
(dogs)
POlHL-08682-15 0015 Regulation of the cardiovascular
system - Projection of autonomic nerves onto the heart
(dog)
POlHL-08805-15 0044 Regulation of ventilation and
pulmonary circulation - Neurochemical Interactions in
respiratory control (human, dogs, goats)
POlHL-08805-15 0045 Regulation of ventilation and
pulmonary circulation - Integrated description of
neurochemical respiratory control system
ROlHL-09154-14 Central control of distribution of organ
blood flow (monkeys)
ROlHL-09913-13 Cerebral velns-AnatomIc and radiologic
correlation (human)
ROlHL-12564-09
(human, dog)
ROlHL-12647-08
Control of respiration and blood gases
Inactivation of norepinephrine in vascularl
Central neural control of cardiovascular
Cardiorespiratory control In exercise
tissue
ROlHL-13187-09
function (cats)
ROlHL-13233-08
(human)
R01HL-1384I-16 Respiration during altitude
acclimatization (goats, dogs, rats, rabbits)
ROlHL-13888-15 Regulation of respiration
P50HL-14214-07 0027 Newborn lung center for hyaline
membrane disease - Oral-laryngeal chemoreceptors and
respiratory failure in newborns (human, sheep)
POlHL-14388-07 0185 Regulation of the circulation in
pathological states - Reflex control of venous tone (human,
rabbits, dogs)
POlHL-14388-07 0186 Regulation of the circulation In
pathological states - Anglotenslon in modulation of
neurogenic vasoconstriction
POlHL-14388-07 0187 Regulation of the circulation in
pathological states - Histamine and circulatory control
(c»nM)
*EKkides routine methodokigy OR covers only general projects which preclude Indexing at the specific level.
"ti'.eTitt <i«nHicantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for Investigator's name and grant number.
INF
POIHI 1438807 0201 Reiulalion ol the ciiculalion in
pathological states Cantial sympathetic discharge in
spontaneously hypertensive rats
POIHL 14388 0/ 0202 Regulation o( the circulation in
pathological states Development ot hypertension in
spontaneoushf hypertensive rats
POIHI 1438807 0203 Regulation ol the circulation in
pathological states Activation ot sympathetic nervous
systems in spontaneously hyperactive rats
POIHL'1438807 0204 Regulation ot the circulation in
pathological states Rellex control of vascular resistance
in spontaneously hypertensive rats
POIHL 14388 07 0208 Regulation of the circulation in
pathological states Baroreceptor reflex function in normal
and hypertensive man
' P01HL14388 07 0209 Regulation of the circulation in
pathological states Neural regulation of vascular
resistance in human hypertension
' POIHL'14414'07 0007 Environmental influences on
cardiorespiratory and cellular functions Neural control of
respiration (human, cats)
' P01HL14414 07 0015 Environmental influences on
cardiorespiratory and cellular functions • Control of the
cardiovascular system (dogs)
' ROIHL 14870-06 Dynamics of oxygen and carbon dioxide
regulation (animals)
' R01HL'lS4e9-06 Human ventilatory adaptation (also.
Cerebral arterial tone and reactivity
Neural control of respiration (cats)
Integrated control of cardiovascular
Control of ventilation in health and
Synaptic chemistry and cardioregulation
dogs, rats)
R01HL'1S80506
(rabbits)
ROlHL'16430-05
ROIHL'16648'16
activity (cats)
P01HL1687805
disease
R01HL1737003
in Limulus
ROIHL 1771504 Respiratory muscle afferents in
respiratory control (cats)
ROlHL-1780004 Pulmonary reflexes- Central pathwrays
(cats, dogs, rabbits)
ROlHL-1808503 Neural factors in atherogenesis (squirrel
monkeys)
ROlHL-18340-04 Electron microscopy of the
juxtaglomerular apparatus (rats)
' R01HL1897603 Blood pressure control-Relation to
behavioral stress (human, dog)
R01HL18995-04 Cardiovascular determinants of
catecholamine release (dogs)
R01HL1924803 Breathing pattern variation and
mechanical influences
R01HL19298-03 Pulmonary hemodynamics (dogs, cats)
' ROlHL-19410-03 Dynamic interrelations underlying
exercise hyperpnea (human)
' ROlHL-2038409 Social stimulation, RNA and
cardiovascular disease (animals)
• ROlHL-20548-02 Innervation of the lung (rats, monkeys)
ROlHL-20678-02 Cardiovascular adaptation to stress in
disease states (dogs)
ROlHL-20766-02
(baboons)
Control of circulation in heat stress
Innervation of the heart-Acetylcholine
ROlHL-21 19502
receptors (frogs)
ROlHL-21532-02 Cardiovascular homeostasis and learning
(frogs, rats, human)
ROlHL-22361-01 Regulation of cardiac adaptation to
exercise (rats)
ROlHL-22740-01 Behavior and cardiovascular disease-
Basic mechanisms (human)
** R23HL-22747-01 Cardiodynamics and hypertension under
cerebellar control (dogs)
** ROlHL-22868-01 Presynaptic regulatory mechanisms in
hypertension (rats, dogs)
INFORAAATION RETRIEVAL
SEE INFORMATION SYSTEMS, INFORMATION RCTRIEVAL
INFORAAATION SYSTEMS (INCL BANKS AND
CENTERS)
SEE ALSO BIOMEDICAL REGISTRIES AND REFERRAL CENTERS
SEE ALSO BIOMEDICAL SYSTEMS AUTOMATED, HEALTH CARE
FACILITIES (SYSTEMS) INFORMATION SYSTEMS
SEE ALSO CHEMICAL AND DRUG INFORMATION SYSTEMS
SEE ALSO HEALTH RECORDS
SEE ALSO HEALTH SCIENCES PROFESSIONS, HEALTH
SCIENCES MANPOWER DATA AND REGISTRIES
SEE ALSO INFORMATION AND COMMUNICATION, AUTOMATIC
DATA PROCESSING
SEE ALSO TISSUE (CELL) CULTURE, CELL CULTURE
COLLECTIONS BANKS AND REGISTRIES
** NOlHI-72947-01 Coordination center-Coronary intervention
** POlHL-0466418 0010 Cardiovascular and lung dynamics
- Lett ventricular dynamics (human)
POlHL-04664-18 0011 Cardiovascular and lung dynamics
- Detection of abnormal segments of the human ventricle
by measure of asynergy
POlHL-04664-18 0015 Cardiovascular and lung dynamics
• Computer system for the cardiovascular laboratory
ROlHL-10582-12 Thrombosis and hemosiasis -Analysis,
methods and standards (human, cattle, venom)
** P50HL-1936202 0017 A/S SCOR -Atherosclerosis in
nonhuman primates - Core laboratory -Data management,
statistical analysis
307
NOIHV 22913 09 lipid resiMrch clinic
NOIHV 5302/ 05 Data coordinating ci-nter for Ihe unstable
angina pectoris study
NOIHV 6294101
LRC programs
NOIHV 62957-05
clinical trials
NOlHV/2979-01 Therapy to protect ischemic myocardium
Data Center
Nutrition coding center lor MRHI and
Coordinating center model for NHLI
INFORAAATION SYSTEAAS, INDEXING
N01HV6294101 Nutrition coding center for MRFII and
LRC programs
INFORAAATION SYSTEAAS, INFORAAATION
RETRIEVAL
SEE ALSO PUBLICATIONS. LITERATURE SURVEY
POIHL 19717 02 0046 Response of the lung to injury
Bioengineering section
ROIHL 1986403 0002 Blood pressure of children and
young adults Data epidemiology center
INFRARED SPECTROAAETRY
SEE CHEMISTRY. ANALYTICAL METHODS. SPECTROMETRY.
INFRARED*
INFRARED THERAAOGRAPHY
SEE TEMPERATURE MEASUREMENT. THERMOGRAPHY*
INFUSIONS, ARTERIAL
SEE DOSAGE AND ROUTE, INFUSIONS ARTERIAL
INFUSIONS, VENOUS
SEE DOSAGE AND ROUTE, INFUSIONS VENOUS
INHALATION
SEE DOSAGE AND ROUTE, INHAUTION
SEE SENSORY DEPRESSION, ANESTHESIA (GENERAL).
INHALATION
SEE THERAPY, INHALATION THERAPY
INHALATION ANESTHESIA
SEE SENSORY DEPRESSION. ANESTHESIA (GENERAL).
INHAUTION
INHALATION DISORDERS FROAA NON-ORGANIC
POLLUTANTS
SEE RESPIRATORY DISORDERS, ENVIRNOMENTAL
POLLUTANTS ASSOCIATED
INHALATION THERAPY
SEE THERAPY. INHALATION THERAPY
INHERITED FACTORS IN HYPERTENSION
SEE CARDIOVASCULAR DISORDERS, HYPERTENSION
(SYSTEMIC), GENaiCSASSOCIATEO
INHIBITING ANTIBODIES
SEE IMMUNOLOGY. ANTIBODIES. BLOCKING ANTIBODIES
INHIBITORS
SEE CALCIFICATION INHIBITORS (CALCIUM NEGATIVE
BALANCE DRUGS)
SEE ENDOCRINOLOGY, HORMONES INHIBITORS
SEE ENZYME INHIBITORS
SEE GROWTH INHIBITORS
SEE NUCLEIC ACIDS INHIBITORS
SEE SULFHYDRYLS INHIBITORS
INJURIES (HAZARDS AND INSULTS)
SEE ALSO ENVIRONMENT. STRESS
SEE ALSO KIDNEY DISORDERS, NEPHROSIS LOWER NEPHRON
SEE ALSO METALS POISONING
M P01HL-06370-17 Cardiopulmonary and renal pathology
research center
** POlHL-06370-17 0006 Cardiopulmonary and renal
pathology research center - Chemical basis of
ultrastructural changes in disease (rats)
** POlHL-063 70-17 0015 Cardiopulmonary and renal
pathology research center ■ Pathogenesis of chemically
induced tissue injury (rats)
P01HL15832-06 0002 Chemical-structural predispositions
to lung injury - Connective tissue in lung in development
and repair of injury (human, rats, mice)
POlHL-15832-06 0010 Chemical-structural predispositions
to lung injury - Kinin generating systems in pulmonary
disease (human, animals)
POlHL-15832-06 0012 Chemical-structural predispositions
to lung injury - Contractile structures and contractility in
cells of lung respiratory tract
** ROlHL-16330-06 Aging-tissue injury and repair (rats)
ROlHL-177 19-03 Lung injury, substrate utilization, oxygen
toxicity (rats, rabbits, dogs)
POlHL-197 17-02 0012 Response of the lung to injury ■
Connective tissue biochemistry and enzyme injury of the
lung (hamsters)
POlHL-20993-02 0006 Population dynamics of arterial
cells in atherogenesis • Mechanism of regression of
atherosclerosis by diet and injury (swine)
** R01HL-2!032-02 Injury, wall thickness, and arterial wall
oxygenation (dogs, rabbits)
** ROlHL-21038-01 Electrically induced cardiac EM-
histochemical changes (animals)
INJ
INJURIES, ACCIDENTS, SUFFOCATION
P'jOHI 14218 0/ 001/ Pulmonary '>(,0R Newborn lung
centor Tiansvascular fluid exchange, vavoactive mediilott
in RDS (sheep, cat)
INJURIES, BACK, SPINAL
ROIHI 21532 02 Cardiovascular homeostasis and learning
(frogs, rats, human)
INJURIES, BURNS
ROIHL 20218 02 Fibrinogen catabolism and intravascular
coagulation (human)
ROIHL 22875 01 Crotalase Chemistry, physiology, cirnical
potential (rats, rabbits)
ROIHL 2361801 Substrate metabolism in isolated
myocytes in shock (dogs, rats, guinea pigs)
INJURIES, BURNS, ELECTRICAL
** ROIHL 2269901 Defibrillation electrode studies (dogs,
swine)
INJURIES, CHEST
SEE ALSO RESPIRATORY DISORDERS. ATELECTASIS
ROIHL 13172 10 Post trauma lung mechanics and fluid
exchange (human, dogs, monkeys)
INJURIES, DYSBARISAA
SEE ALSO ENVIRONMENT, ATMOSPHERIC PRESSURE
SEE ALSO ENVIRONMENTAL CHAMBER CONTROLLED.
HYPERBARIC FACILITY
SEE ALSO RESPIRATORY GAS LEVELS
SEE Also WATER ENVIRONMENT. DIVING AND SWIMMING
M P01HL07896 15 Environmental biomedical research
program
** P01HL07896 15 0008 Environmental biomedical research
program Otologic studies under hyperbaric conditions
(human, animals)
** POIHL 07896-15 0009 Environmental biomedical research
program - Decompression sickness and computation of safe
diving tables (human, animals)
** POlHL-07896-15 0032 Environmental biomedical research
program ■ Fluorometry study of brain exposed to hyperbaric
oxygen (dogs, cats)
** P01HL07896-15 0050 Environmental biomedical research
program - Fundamental decompression concepts using the
rat animal model
** POlHL-07896-15 0057 Environmental biomedical research
program - Effects of dipyridamole and aspirin on
decompression thrombocytopenia (human)
M POlHL-0889914 Tolerance to respiratory gases in health
and disease
POlHL-0889914 0029 Tolerance to respiratory gases in
health and disease Isobaric gas counter diffusion
phenomena (human, pigs)
POlHL-08899-14 0056 Tolerance to respiratory gases in
health and disease ■ Extension of pulmonary oxygen
tolerance at increased pressures (animals)
** POlHL-08899-14 0072 Tolerance to respiratory gases in
health and disease ■ Inert gas exchange isobaric gas
counterdiffusion and decompression
** POlHL-08899-14 0073 Tolerance to respiratory gases in
health and disease - Biophysical mechanisms involved in
isobaric gas counterdiffusion syndrome
** POlHL-08899-14 0074 Tolerance to respiratory gases in
health and disease - Biomathematical analysis of isobaric
gas exchange and bubble formation
** P01HL08899-14 0075 Tolerance to respiratory gases in
health and disease - Gas diffusion rates and bubble
formation across membranes (animals)
** POlHL-08899-14 0076 Tolerance to respiratory gases in
health and disease - Bubble formation during gas
counterdiffusion (hamsters)
** POlHL-08899-14 0077 Tolerance to respiratory gases in
health and disease - Isobaric gas supersaturation patterns
** P01HL08899-14 0078 Tolerance to respiratory gases in
health and disease - Isobaric gas counterdiffusion -Sensory,
cutaneous and systemic function (animals)
** P01HL08899-14 0079 Tolerance to respiratory gases in
health and disease • Physiological factors in
counterdiffusion bubble formation (human, pigs)
** POlHL-0889914 0080 Tolerance to respiratory gases in
health and disease • Dynamic quantitation of continuous
isobaric gas embolization
** POlHL-0889914 0085 Tolerance to respiratory gases in
health and disease - Search for gas bubbles in vestibular
fluids (animals)
** ROlHL-16254-05 Pathogenesis of bubble and clot
formation (fish)
** ROlHL-17503-03 Vascular bubbles in decompression
sickness (minipig. dog, goat)
** ROlHL-22406-01 Isobaric vascular bubbles and
decompression sickness (goats, models)
** ROlHL-22413-01 Enhanced detection of bubbles in
Doppler flow signals (human)
INJURIES, DYSBARISAA, INERT GAS NARCOSIS
M POlHL-07896-15 Environmental biomedical research
program
** POlHL-0789615 0029 Environmental biomedical research
program - Oxygen-helium diving resulting in high pressure
nervous syndrome (human, animals)
** POlHL-0789615 0030 Environmental biomedical research
program - Narcosis caused by inert gases at raised
pressures (human, animals)
(contd)
•Excludes routine methodology OR covers only general projects which preclude
**Oriented significantly to above subject.
indexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
■■jBn»jag«,'ti%sfMija.'-
INJ
308
INT
M POlHL-08899-14 Tolerance to respiratocy gases in health
and disease
P01HL-08899-U 0007 Tolerance to respiratory gases in
health and disease - Effects of high oxygen pressures on
visual function (human, animals)
** P01HL08899-14 0064 Tolerance to respiratory gases in
health and disease - Narcotic effects of inert gases on
functional systems (rats)
** P01HL0889944 0065 Tolerance to respiratory gases in
health and disease - Adaptation and effects of narcotic
gases exposure (human)
" P01HLQ889914 0066 Tolerance to respiratory gases in
health and disease - Neurophysiological effects of inert
gases in man
** POlHL-0889914 0067 Tolerance to respiratory gases in
health and disease - Inert gas influences upon visual
function in man
" P01HL0889914 0072 Tolerance to respiratory gases in
health and disease - Inert gas exchange isobaric gas
counterdiffusion and decompression
" POlHL-08899-14 0089 Tolerance to respiratory gases in
health and disease Decompression by applications of
optimal control theory
ROlML-12564-09 Control of respiration and blood gases
(human, dog)
M ROlHL'17896-03 Oehydropeptide renin substrates
INJURIES, EYE
** POlHL-08899 14 Tolerance to respiratory gases in health
and disease
INJURIES, HEAD AND NECK
SEE ALSO BRAIN INJURY
P01HL-1385M6 Cyclotron produced isotopes in biology
and medicine (human, animals)
INJURIES, SCARS
POlHL-03174-23 0007 Mechanisms of acute vascular
reaction to injury - Healing of injured myocardium-Basal
lamina scaffold (human, rats, dogs)
POlHL-13737-07 0030 Assisted circulation - Myocardial
ischemia-Effects of phase-shift balloon pumping (dogs)
** POlHL-13737-07 0038 Assisted circulation ■
Distinguishing the ischemic ventricle from scarred ventricle
by balloon pumping
R01HL18473-04 Genesis of atherosclerotic lesions
(human, mules)
ROlHL-18714-04 Cardiovascular matrix-Morphogenesis
and maturation (human, chick embryo, mammal)
INJURIES, SHOCK
SEE ALSO CARDIOVASCULAR DISORDERS, HEMORRAGIC
SHOCK
SEE ALSO CARDIOVASCULAR FUNCTION, BLOOD FLOW,
REACTIVE HYPEREMIA
SEE ALSO HEART DISORDERS, CARDIOGENIC SHOCK
SEE ALSO HYPERSENSITIVITY, ANAPHYUXIS
SEE ALSO RESPIRATORY DISORDERS, RESPIRATORY
INSUFFICIENCY, SHOCK LUNG
*" ROlHL-07723-15 Reflex control of vascular capacitance in
shock
POlHL-08682-15 0019 Regulation of the cardiovascular
system - Hepatic immunophysiology and host-defense in
shock (rat, dog, human)
POlHL-08682-15 0020 Regulation of the cardiovascular
system ■ Hepatic metabolic basis of shock (rat)
POlHL-1 1310-12 0067 Mechanisms of cardiovascular
disease • Cardiac performance viith measured
homodynamic variables (human)
** POlHL-1 1678-11 0043 Cardiovascular dynamics and their
control - Basic mechanisms of circulatory snock (dog)
** ROlHL-13341-06 Lymph -An indication of splanchnic tissue
respiration (dogs, human, rats)
ROlHL-14693-07 Survival value of physiological responses
to hypoxia (dogs)
ROlHL-15676-06 The role of occult myocardial failure in
human shock (human, dogs)
ROlHL-16916-04 0001 The role of albumins in lung v»ater
accumulation - Capillary permeability (dogs, human)
P60HL-1 7269-04 0024 National heart and blood vessel
research and demonstration center - Section of
experimental cardiovascular surgery-Core facility
** ROlHL-17458-04 Renal control of sodium excretion (rats)
ROIHL- 18002-03 Circulatory shock, trauma and RE-system
function (rats)
** ROIHL 19673-03 Surgical aspects of shock and hypoxia
(dogs, monkeys, rats)
R01HL-20196-02 Regulation of coronary arterial smooth
muscle
** ROIHL-23618-01 Substrate metabolism in isolated
myocytes in shock (dogs, rats, guinea pigs)
INJURIES, SHOCK ENDOTOXIC
SEE BLOOD TOXICOLOGY, BACTEREMIA-SEPTICEMIA
INJURIES, SHOCK, TOXIC
SEE ALSO BLOOD TOXICOLOGY, BACTEREMIA-SEPTICEMIA
** ROlHL-18731-02 RES stimulating materials in
experimental shock (dogs)
INJURIES, SURGICAL WOUND INFECTION
ROlHL-21632-02 Development of a transcutaneous pov»er
transfer system (cattle)
INJURIES, SURGICAL WOUNDS
POlHL-17417-05 0006 Experimental lung transplantation
- Bronchial anastomotic problems and increases donor lung
availability (dog)
ROlHL-22113-02 Micro/macrovasculature in healing of
foot lesions (human)
INJURIES, TEMPERATURE DEPENDENT, HEAT
INDUCED
SEE ALSO ENVIRONMENT, STRESS, HEAT INDUCED
SEE ALSO INJURIES. BURNS
ROIHL- 180 10-04 Capillary transport of large molecules
(dogs, sheep)
ROlHL-18932-03 Brain microcirculation observed in vivo
after trauma (mice)
ROlHL-20634-01 Blood volume and venous return in
thermal strain (human)
ROlHL-22699-01 Defibrillation electrode studies (dogs,
swine)
INJURIES, TRAUMA
SEE ALSO INJURIES, HEAD AND NECK
SEE ALSO KIDNEY DISORDERS, NEPHROSIS LOWER NEPHRON
SEE ALSO RESPIRATORY DISORDERS, RESPIRATORY
INSUFFICIENCY, SHOCK LUNG
POlHL-031 74-23 0001 Mechanisms of acute vascular
reaction to injury - Response of the vascular intima to
injury (human, rats)
** ROlHL-131 72-10 Post-trauma lung mechanics and fluid
exchange (human, dogs, monkeys)
** ROlHL-13193-09 Pathophysiology of post-traumatic and
shock states (rodents, dogs)
ROlHL-13466-08 Pulmonary platelets in shock, trauma
and embolization (dogs, pigs, rats)
P50HL-142 17-08 0050 Specialized center of research in
thrombosis - Electron microscopy section (dogs)
ROlHL-1691604 0001 The role of albumins in lung water
accumulation Capillary permeability (dogs, human)
ROlHL-16916-04 0011 The role of albumins in lung water
accumulation - Whole body distribution and exchange of
albumin (rabbits, human, monkeys)
** P60HL- 17265-04 0007 Community blood resource center
support - Research -Massive transfusion and trauma
(human)
ROIHL-17355-04 Pulmonary vascular adjustments in
circulatory collapse (dogs, rats)
** R01HL-18002-03 Circulatory shock, trauma and RE-system
function (rats)
ROlHL'18015-03 Pharmacologic studies on vascular
smooth muscle (dogs, rats)
** POlHL-18576-03 0001 Thrombosis research program
project - Platelet damage from physical forces and
artificial surfaces (human)
R01HL-18e72-03 Dynamic studies of clot structure
formation (human)
R23HL-22437-01 Leukotactic mediators in lung
inflammatory reactions (rats, rabbits, human)
ROlHL-22562-02 Mechanism of cardiac action potential
propagation (tunicates)
INJURIES, WOUND HEALING
SEE ALSO GROWfTH AND DEVELOPMENT, REGENERATION
** POlHL-03174-23 0007 Mechanisms of acute vascular
reaction to injury - Healing of injured myocardium-Basal
lamina scaffold (human, rats, dogs)
** POlHL-07896-15 0046 Environmental biomedical research
program - Treatment of radiation induced tissue injury by
hyperbaric oxygen (human)
** POlHL-11414-11 0037 Thrombosis and atherosclerosis
program - Vascular intlmal injury and healing (rabbits,
rats)
ROlHL-14126-17 Effect of function on grafts and implants
of collagen (dogs, monkeys)
** POlHL-16387-04 0003 The blood vessel and
thrombogenesis - Blood vessel healing (rabbits)
POIHL- 174 17-05 0006 Experimental lung transplantation
- Bronchial anastomotic problems and increases donor lung
availability (dog)
** ROlHL-1 7747-04 Endothelial injury and regeneration (rats)
ROlHL-184 73-04 Genesis of atherosclerotic lesions
(human, mules)
** ROlHL-21735-01 Electrophysiology after healed myocardial
infarction (cats)
** ROlHL-21994-01 Structure and development of
regenerating capillaries (rabbits, chick embryo)
** ROlHL-221 10-02 Healing complications in vascular
grafting (dogs)
** ROlHL-221 13-02 Micro/macrovasculature in healing of
foot lesions (human)
POlHL-22602-01 0003 Pathophysiology of the
endothelium - Mechanisms of endothelial proliferation
(human, animals)
INJURIES, WOUNDS
SEE ALSO INJURIES, SURGICAL WOUNDS
ROlHL-12869-09 Arterial metabolism, diabetes and
atherogenesis (rats, rabbits)
INNER EAR
SEE EAR. LABYRINTH
INNERVATION (GENERAL)
SEE NERVOUS SYSTEM, NERVES, INNERVATION (GENERAL)
INNERVATION HEART
SEE NERVOUS SYSTEM AUTONOMIC, HEART INNERVATION
INOSINE
SEE PURINE NUCLEOSIDES, HYPOXANTHINE NUCLEOSIDES,
INOSINE
INOSINE MONOPHOSPHATE
SEE PURINE NUCLEOTIDES, HYPOXANTHINE NUCLEOTIDES.
INOSINE MONOPHOSPHATE
INOSITOL
SEE SUGAR ALCOHOLS, HEXITOLS, INOSITOL
INOSITOL PHOSPHATES
SEE SUGAR ALCOHOLS. HEXITOLS. INOSITOL PHOSPHATES
INOTREX
SEE PHENYLALKYLAMINES. CATECHOLAMINES, DOBUTAMINE
INOTROPIC AGENTS NEGATIVE
SEE MUSCLE RELAXANTS
INOTROPIC AGENTS POSITIVE
SEE MUSCLE STIMUUNTS
INSECTS BITES STINGS VENOMS
SEE TOXICOLOGY, ANIMAL POISONS, INSECTS BITES STINGS
VENOMS
INSOMNIA
SEE NEUROLOGIC MANIFESTATIONS, SLEEP DISORDERS
INSTRUMENTATION CENTERS
SEE BIOMEDICAL ENGINEERING, INSTRUMENTATION CENTERS
INSTRUMENTATION CLINICALLY ORIENTED
SEE BIOMEDICAL ENGINEERING, INSTRUMENTATION
CLINICALLY ORIENTED
INSTRUMENTATION NOT CLINICAUY ORIENTED
SEE BIOMEDICAL ENGINEERING, INSTRUMENTATION NOT
CLINICALLY ORIENTED
INSULIN
SEE PANCREAS HORMONES, INSULIN
INSULIN INHIBITORS
SEE PANCREAS HORMONES, INSULIN INHIBITORS
INSULIN (RESISTANCE) TOLERANCE
SEE CARBOHYDRATES METABOLISM DISORDERS, DIABETES.
INSULIN (RESISTANCE) TOLERANCE
INSURANCE
SEE HEALTH INSURANCE
SEE SOCIOECONOMICS, FINANCING ORGANIZED, INCOME
INSURANCE
INTEGRATIVE CONTROL (NEURAL)
SEE INFORMATION PROCESSING AND CONTROL (NEURAL)
INTELLIGENCE
SEE PSYCHOLOGY, PERFORMANCE, INTELLIGENCE
INTELLIGENCE, ARTIFICIAL
SEE COMPUTER, ARTIFICIAL INTELLIGENCE, PAHERN
RECOGNITION AND CONTROL SYSTEMS
INTENSIVE CARE UNITS
SEE HOSPITALS, INTENSIVE CARE UNITS
INTERACTIONS
SEE DRUGS AND PHYSICAL AND/OR CHEMICAL AGENTS
INTERACTION
SEE DRUGS INTERACTION
SEE PHYSICAL AND/OR CHEMICAL AGENTS INTERACTION
(BIOLOGICAL AND ECOLOGICAL)
INTERATOMIC FORCES NONBONDING
SEE MOLECULAR INTERACTIONS NONBONDING
INTERATRIAL AND INTERVENTRICULAR SEPTA
SEE HEART, SEPTUM
INTERCALATED DISCS
SEE HEART, MYOCARDIUM INTERCALATED DISCS
INTERCELLULAR BRIDGES, CONNECTIONS
SEE CELL-CELL INTERACTION, INTERCELLULAR CONNECTIONS-1
JUNCTIONS
INTERCELLULAR JUNCTIONS
SEE CELL-CELL INTERACTION, INTERCELLULAR CONNECTIONS-I
JUNCTIONS
INTERCELLULAR SPACE
SEE BODY FLUIDS, EXTRACELLULAR SPACE (COMPARTMENT)
INTERCOSTAL MUSCLES
SEE RESPIRATORY MUSCLES
INTERFEROMETRY
SEE OPTICS, INTERFEROMETRY*
INTERFERON
SEE IMMUNOLOGY, INTERFERON
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
INTERNAL CONTROL (AUTOGENIC
CONDITIONING)
SEE PSYCHOLOGY, C0N0I1I0NING, AUIOGfNIC ^0 INURNAl
CONIROL
INTERNAL RESPIRATION
SEE RESPIRATION INTERNAL
INTERNATIONAL HEALTH AND SCIENTIFIC
ORGANIZATIONS
SEE HEALTH AND SCIENTIflC. ORGANIZATIONS.
INTERNATIONAL
INTERNATIONAL MEETINGS
SEE INEORMATION DISSEMINATION, MEETINGS CONFERENCES
SYMPOSIA, INTERNATIONAL
INTERPERSONAL BEHAVIOR, RELATIONS
SEE PSYCHOLOGY SOCIAL, INTERPERSONAL RELATIONS
INTERSTITIAL PNEUMONIA, ACUTE
SEE RESPIRATORY DISORDERS. PNEUMONIA VIRAL
INTERSTITIAL PNEUMONITIS, ALLERGIC
SEE RESPIRATORY DISORDERS, PNEUMONITIS ALLERGIC
INTERSTITIAL
INTERVENTRICULAR HEART BLOCK
SEE HEART DISORDERS, ARRHYTHMIA, HEART BLOCK.
BUNDLE BRANCH
INTERVENTRICULAR SEPTUM
SEE HEART, SEPTUM
INTESTINAL DISORDERS
SEE GASTROINTESTINAL DISORDERS, INTESTINAL DISORDERS
(GENERAL)
INTESTINAL FLORA (BACTERIA)
SEE BACTERIA, ENTERIC (GENERAL)*
INTESTINAL MUCOSA
SEE GASTROINTESTINAL SYSTEM, INTESTINES. MUCOSA
INTESTINAL VILLI
SEE GASTROINTESTINAL SYSTEM, INTESTINES, MUCOSA, VILLI
INTESTINES
SEE GASTROINTESTINAL SYSTEM. INTESTINES
INTRACARDIAC PRESSURES
SEE HEART FUNCTION. INTRACARDIAC PRESSURE
INTRACARDIAC VOLUME
SEE HEART FUNCTION. INTRACARDIAC VOLUME
INTRACEUULAR FLUID
SEE CELL FLUIDS
INTRACELLULAR MEMBRANES
SEE CELL COMPONENTS. INTRACELLULAR MEMBRANES
INTRACRANIAL PRESSURE
SEE NEUROPHYSIOLOGY. INTRACRANIAL PRESSURE
INTRACRANIAL VENOUS SINUSES
SEE CEREBROVASCULAR SYSTEM, VENOUS SINUSES
INTRACRANIAL
INTRATHORACIC PRESSURE
SEE RESPIRATORY FUNCTION. RESPIRATION. THORACIC
PRESSURE
INTRAVASCULAR COAGULATION DISSEMINATED
SEE BLOOD COAGULATION DISORDERS. INTRAVASCULAR
COAGULATION DISSEMINATED
INTRAVENOUS FEEDING
SEE NUTRITION, DIET SCHEDULE AND ROUTE. PARENTERAL
FEEDING
INTRINSIC SURFACE ACTIVITY OF MEMBRANES
SEE MEMBRANE SURFACE (BIOLOGICAL) ACTIVITY (GENERAL)
INULIN
SEE HEXOSANS. LEVANS. INULIN
IN UTERO DIAGNOSIS
SEE PREGNANCY. ANTEPARTUM DIAGNOSIS
INVOLUNTARY MOVEMENTS
SEE NEUROMOTOR DISORDERS
lODINATION-DEIODINATION
SEE HALOGENATION. lODINATION-DEIODINATION
IODINE RADIOISOTOPES (123,124,125,131,132,
133)
SEE RADIOISOTOPES. IODINE
lODO FATTY ACIDS
SEE HALO FATTY ACIDS. lODO FATTY ACIDS
ION BALANCE (BODY FLUIDS)
SEE BODY FLUID BALANCE. IONIC
ION CARRIERS
SEE BIOLOGICAL TRANSPORT. ION EXCHANGE AND
TRANSPORT. ION CARRIERS (lONOPHORES)
309
ION EXCHANGE AND TRANSPORT
Sff BIOIOGICAI TRANSPORT ION EXCHANGi AND
TRANSPORI
ION EXCHANGE CHROMATOGRAPHY
SFE PHYSICAl SEPARATION. CHROMATOGRAPHY. ION
EXCHANGE*
ION PUMPS
SEE BIOLOGICAL TRANSPORT, ACTIVE TRANSPORT, ION
PUMPS
ION PUMP INHIBITORS
SEE BIOLOGICAL TRANSPORT, TRANSPORT EFFECTORS
IONIC BONDS
SEE CHEMICAL BONOS. IONIC
IONIC CFM MODEL
SEE BIOLOGICAL TRANSPORT, MEMBRANE MODELS
IONIC CONDUCTANCE CHANNELS
SEE BIOLOGICAL TRANSPORT, MEMBRANE PERMEABILITY
AND TRANSPORT
IONIC STRENGTH
SEE ALSO ACIDS BASES, HYDROGEN-ION CONCENTRATION
RCIHL 16927 05 Structure and function oT normal and
abnormal hemoglobin (human)
P60HL-17269-04 0018 National heart and blood vessel
research and demonstration center Mitochondria and
energetics (rabbits, dogs)
P01HL19737-02 0004 Cellular and molecular aspects of
respiratory physiology Rapid reactions and erythrocyte
exchanges of blood during respiratory transport
P01HL-20592-02 0012 Cell biology of cardiac and
skeletal muscle - Contractile properties of skinned muscle
fibers (frogs)
POlHL-20994 02 C009 Dynamics of neutrophil elastase in
the lung - Biosynthesis and degradation of elastin in
emphysema (human, hamsters)
POlHL-2 10 16-02 0007 Sickle cell anemia and other
hemoglobinopathies - Cellular determinants of red cell
sickling
POlHL-210 16-02 0009
hemoglobinopathies
Sickle cell anemia and other
Nitrogen mustards and their potential
use as antisickling agent
ROlHL-213 12-01 Sarcomere mechanics in disrupted
ventricular muscle (guinea pigs)
RClHL-23183-01 Voltage dependent conductance in
membranes
IONIZATION
P01HL-12I57-11 0038 Functions and mechanisms of cell
membrane ion transport - Mechanisms and interactions of
gases and ions with bilayer membranes (human)
P60HL-1 7269-04 0016 National heart and blood vessel
research and demonstration center - New analytical
methodology for atherosclerosis studies
IONIZING RADIATION
SEE RADIATION. IONIZING RADIATION
lONOPHORES
SEE BIOLOGICAL TRANSPORT. ION EXCHANGE AND
TRANSPORT. ION CARRIERS (lONOPHORES)
IONS
SEE ALSO ACIDS-BASES. ISOELECTRIC POINT
SEE ALSO MOLECULAR POURITY
R01HL-00082-30 Transmembrane movements (barnacles,
frogs, rats)
** POlHL-12157-11 0038 Functions and mechanisms of cell
membrane ion transport - Mechanisms and interactions of
gases and ions with bilayer membranes (human)
R01HL-18004-02 Transport through arterial wall-
Biophysical aspects (rabbits)
** ROlHL-18199-03 Effects of ions on vascular reactivity
ROlHL-20278-02 Cellular mechanisms of renin secretion
(rats)
ROlHL-21038-01 Electrically induced cardiac EM-
histochemical changes (animals)
IONS, ANION
ROlHL-00759-29 Regulation of electrolyte and acid base
equilibrium (dogs)
ROlHL-08893-14 Structure and function of membrane
proteins (human)
** ROlHL-09906-13 0022 Membrane transport processes in
red blood cells - Anion transport in dog and cat red cells
** ROlHL-09906-13 0023 Membrane transport processes in
red blood cells • Cation and anion movements in two sub-
groups of dog erythrocytes
ROlHL-13567-06 Ion transport across cell membranes
(human)
ROlHL-143 13-07 Apoproteins of triglyceride rich
lipoproteins (human, squirrel monkeys, rats)
POlHL-14388-07 0191 Regulation of the circulation in
pathological states - Regulation of chloride transport in
epithelial membranes (turtles)
R01HL174 11-04 Molecular studies of red blood cell
spectrin (human)
ROlHL-17828-04 Kinetic studies of hemerythrin reactions
(marine worms)
** ROlHL-17878-04 Structural studies of the human
erythrocyte membrane
ROIIH 18619 03 Traniferrin iron binding ind Irantport
piopsrtiet (chicken, rabbit, human)
ROIHI 2036!) 03 Molecular mechannmj of anion Irintport
POIHL 7059? 07 0003 Cell biology of cardiac and
skeletal muscle Cellular magneMum and anion activitiei
in ion specific microeleclrodei (frog-.)
ROIHL 2072b 02 Mechanisms and cellular funclionj of ion
transport
ROIHI 71014 01 Mechanism of the inotropic action of
cardiac glycosides
ROIHL 21 170 01 Molecular structure of human serum
transferrin
ROIHL 21525 02 Effect of cations, anions and water upon
blood vessels (dogs, rats)
ROIHL 2239001 Effect of chloride on renin (rals, dogs)
Regulation of metabolism by drugs and
Biochemistry of muscle contraction (rats.
IONS, CATION
ROIHL 01813-25
hormones (rats)
ROIHL 05949 18
rabbits)
POIHL 06308 18 0025 Mechanisms and therapy of
circulatory disease Subcellular calcium pools in the
genesis of arrhythmias (dogs)
POlHL-06314 17 0046 Immunologic mechanisms in
cardiovascular disease Mediators of immune injury
(human, mice)
POIHL 06314 17 0053
cardiovascular disease
Immunologic mechanisms in
Cellular functions controlled by
cyclic GMP (human, mice, guinea pigs)
POlHL-06314-17 0057 Immunologic mechanisms in
cardiovascular disease Antigens in cardiovascular disease
(human)
POlHL-08899-14 0052 Tolerance to respiratory gases in
health and disease - Oxygen eftects on auditory and
vestibular function (human, guinea pigs)
ROIHL 09906 13 0023 Membrane transport processes in
red blood cells - Cation and anion movements in two sub-
groups of dog erythrocytes
POIHL 11351-12 0001 Cellular and molecular
mechanisms of myocardial function Ionic control of
myocardial contractility (animals)
POlHL-1 1351-12 0010 Cellular and molecular
mechanisms of myocardial function - Basic ionic exchange
studies (rats)
POlHL-11351-12 0013 Cellular and molecular
mechanisms of myocardial function - Ion exchange in the
perfused septum high-resolution technique (rabbits, rats)
POlHL-13262-07 0015 Arterial wall in atherosclerosis -
Crosslinkage biosynthesis in aortic elastin and collagen
(animals)
ROlHL-13375-09 Cellular potential changes causing
cardiac arrhythmias (dogs)
' ROlHL-14092-07 Homeostatic regulation of plasma choline
(rats. dogs, chickens)
' POlHL-14388-07 0151 Regulation of the circulation in
pathological states - Catecholamine release in potassium
ion-free contractures in the caudal artery
' POlHL-14388-07 0152 Regulation of the circulation in
pathological states - Ion flux alterations in caudal artery in
SHR
POlHL-14388-07 0154
pathological states
contraction (rats)
POlHL-14388-07 0172
pathological states
Regulation of the circulation in
Energetics of smooth muscle
Regulation of the circulation in
cAMP-dependent protein kinase from
heart and vascular smooth muscle (guinea pigs)
P6OHL-15157-07 0018 Comprehensive center tor sickle
cell disease - Red blood cell membrane physiology in sickle
cell anemia (human)
POIHL- 15835-06 0021 Study of muscles related to heart
disease - Fast kinetic studies in muscle subcellular
organelles (animals)
POlHL-16117-05 0007 Ion movements and membranes in
cardiovascular control - Physiological and molecular
properties of ionophores (dogs, rabbits)
POlHL-16607-05 0001 Calcium ion and control of
cardiovascular function - Bilayer lipid membranes,
antibiotic probes, and SR function
POlHL-16607-05 0003 Calcium ion and control of
cardiovascular function - Calcium transport in
sarcoplasmic membranes (animals)
ROlHL-16674-05 Airborne metals and lung permeability
(bullfrogs, rats)
P01HL-16683-04 0001 Function and growth of cardiac
and skeletal muscle - Light chains of the skeletal and
cardiac myosin molecule (rabbits, frogs)
ROlHL-16746-04 Design of ion-selective molecules
P01HL-16833-04 0016 Hemoglobin and red cell system in
hemoglobinopathies - Calcium-indiced membrane damage
in Hb SS disease (human, animals)
P60HL-17269-04 0017 National heart and blood vessel
research and demonstration center - Cell membrane (dogs,
rabbits)
ROlHL-18003-05 Digitalis-Mechanism and reversal studies
(dog. sheep, duck, guinea pig. human)
ROlHL-18070-04 Regulation of intrapulmonary airways
and vessels (human, animals)
ROlHL-18077-04 Smooth muscle cell organization and
Ca20 concentration control (chickens)
ROlHL-18711-03 Electrophysiology of heart cells (rats,
chicks)
(contd)
*E»cludes routine methodotogy OR covers only general projects which preclude indexing at the specific level.
**Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number
.VWJUJEKVUVM^ -
ION
310
IRO
ROlHL'19138-03 Contractile activation of skinned cardiac
cells (mammals)
POlHL-19242-02 0009 Study of vascular smooth muscle ■
Electrophysiology of vascular smooth muscle (rats, chick
embryo)
POlHL-19259-03 0004 Digoxin-specific antibody in human
therapy - Digitalis-specific antibodies pharmacological
studies (human, dogs, sheep)
R23HL19601-01 Cardiac response to chronic metabolic
acidosis (rats)
R01HL19653-03 Circulatory system effects of angiotensin
analogs (rats)
ROlHL'19982-02 Blood coagulation -Protein-metal ion-lipid
interactions
ROlHL-2047103 Atherosclerosis and diabetes mellitus
(human)
ROlHL-20725-02 Mechanisms and cellular functions of ion
transport
P60HL-20985-01 0004 Northern California sickle cell
center - Characterization of irreversibly sickled cells
(human)
ROlHL-21136-02 Ion activities and transport in cardiac
muscle cells (sheep)
** ROlHL-21179-01 Volume regulation -Role of the membrane
potential (amphiuma)
R23HL-21196-02 Digitalis induced arrhythmia and NAO KO-
atpase activity (dogs)
R23HL-2 1262-02 Sodium-calcium Interactions in
mammalian myocardium (rabbits, cats)
R01HL-21294-02 Voltage clamp of isolated cardiac
Purkinje cells (dogs)
** R01HL-21371-02 Energy loss microanalysis of myocardial
cations
ROlHL-21493-02 Contractility in cardiac failure (hamsters)
** ROmL-21525-02 Effect of cations, anions and water upon
blood vessels (dogs, rats)
ROlHL-22231-02 IVIodulation of calcium control of cardiac
myofibrils (rats)
ROlHL-22264-01 Regulation of contraction in vascular
smooth muscle (dogs)
POlHL-226 19-01 0001 Cellular mechanisms of heart
failure - Cell membrane isolation and reconstitution (dogs,
lambs)
POlHL-22619-01 0002 Cellular mechanisms of heart
failure - Structure of sodium, potassium-adenosine
triphosphatase (lambs, dogs)
POlHL-22619-01 0004 Cellular mechanisms of heart
failure - Mechanism of action of Na, K-ATPase (sheep,
cattle)
R01HL-2311S-01 Regulation of active sodium transport
(frogs, rats)
IONS, CATIONS, DIVALENT
SEE ALSO METALS, DIVALENT METALS
P50HL-14147-08 0003 Specialized center of research in
thrombosis - Surface thrombogenicity and phospholipid
vesicle physical properties
POlHL-15596-05 0012 Coagulation, fibrinolysis,
hemostasis and hepatitis - Platelet function -Phorbol ester
and zymosan-induced release activity
R01HL-16101-0S Protein-lipid interaction (bacteria,
models)
POlHL-1611705 0003 Ion movements and membranes in
cardiovascular control - Fast kinetic study of calcium
membrane interactions
ROlflL-20902-02 Studies on marginal band system of
erythrocytes (amphibians, reptiles, fish)
R23HL-212 13-01 A model for calcium homeostasis in
excitable tissue (marine worms)
ROlHL-22486-01 Enzyme regulation in cultured arterial
cells (swine)
IONS, ELECTROLYTES
SEE ALSO BODY FLUID BAUNCE, IONIC
** ROlHL-00340-29 Electrolyte disturbance in cardio-renal
disease (human, dogs, rats)
** ROlHL-007 59-29 Regulation of electrolyte and acid base
equilibrium (dogs)
ROlHL-01486-23 Quantitative study of T-wave mechanisms
(human, rabbits, dogs, chickens)
ROlHL-02363-20 Kinetics of water and electrolytes in
shock (dogs, rats)
** ROlHL-03303-21 Factors regulating electrolyte excretion by
the kidney (human, dogs)
R01HL04457-20 Cellular aspects of active transport (fish,
rabbits, anurans, turtles)
P01HL-0789ei3 0030 Environmental biomedical research
program - Narcosis caused by inert gases at raised
pressures (human, animals)
** POlHL-08682-15 0036 Regulation of the cardiovascular
system - Electrolyte transport in myocardium with
hemorrhagic shock (rats)
ROlHL-09234-13 Amino acids of contractile proteins of
failing hearts (dogs, hamsters)
ROlHL-09911-12 Hormonal and dietary modification of
NaCl toxicity (rats) mice)
ROlHL-09914-13 The myocardium In diabetes mellitus
(dogs, monkeys)
R01HL-0992M3 Mechanism* related to congestive heart
failure (dogs, humin, rat)
•* P01HL-n35M2 OOIB Cillulir and molecular
michinlimi of myoctrdlal function • Quantitative
localization of alacttolytai In cardiac tissue
Electrolyte physiology and respiratory
Vascular ion transport and hypertensive
Intrarenal regulation of sodium
POlHL-11678-11 0034 Cardiovascular dynamics and their
control - Renal function curves in intact dogs
P50HL-14147-08 0015 Specialized center of research in
thrombosis - Charge related properties of phospholipid
surfaces in monolayers and vesicles
ROlHL-14148-07 0007 The regional circulations - Salivary
composition in hypertension (human)
** POlHL-14388-07 0159 Regulation of the circulation in
pathological states - Early drug and diet interventions and
blood pressure development (rats)
POlHL-14388-07 9003 Regulation of the circulation in
pathological states - Electron probe projects
** ROlHL-15810-06
acid-base (dogs)
ROIHL 15852-06
mechanisms
ROlHL-16658-05
reabsorption
ROlHL-17705-04 Kallikrein-kinin system In hypertension
(human, rats, dogs)
ROlHL'18579-03 Vasoactive hormones and blood pressure
regulation (dogs, rats, rabbits)
** ROlHL-18891-02 Electrolyte Intake and blood pressure in
hypertension (human)
ROlHL-19139-03 Dispersion of diffusible indicators in the
body (human, cats, dogs)
ROlHL-19674-02 Electrolyte permeability of single
capillaries (frogs)
ROlHL-19677-03 Venous structure and function (dogs)
ROlHL-19858-03 UMMC -Blood pressure precursors and
consequences (human)
ROlHL-19984-02 Blood pressure and immunogenetic
factors in the young (human)
ROlHL-202 06-02 Carbohydrates-nucleotides and adrenergic
interactions (rabbits, cats, rats)
ROlHL-20211-02 Role of taurine in the heart (dogs, rats,
mice)
ROlHL-20720-02 Myocardial protection during
cardiopulmonary bypass (dogs)
R23HL-2 1 150-02 Regulation of airway mucous glands and
ion transport (dogs, ascaris)
ROlHL-221 77-02 Mechanisms of control of pulmonary
smooth muscle (dogs)
** ROlHL-22281-01 Microprobe analysis and metabolite
levels of ischemic mycardium (dogs)
ROlHL-2256902 Intestinal secretion-Capillary and tissue
forces (dogs, cats)
ROlHL-22594-01 Reflex control of the circulation in heart
failure (dogs)
ROlHL-22990-01 Angiotensin II receptors-Mechanisms of
regulation (rats)
IONS, ELECTROLYTES, NON ELECTROLYTES
ROlHL-14820-07 Factors affecting physiology of biological
membranes (human)
IONS, ELECTROLYTES, POLYELECTROLYTES
POlHL-06314-17 0047 Immunologic mechanisms in
cardiovascular disease - Role of Intravascular coagulation
(human, animals)
POlHL-15596-05 0008 Coagulation, fibrinolysis,
hemostasis and hepatitis - Structural studies and
fractionation of antihemophilic factor (human)
POlHL-15596-05 0010 Coagulation, fibrinolysis,
hemostasis and hepatitis - Von Willebrand's factor (human)
POlHL-15596-05 0016 Coagulation, fibrinolysis,
hemostasis and hepatitis - Hepatitis-B antigen in whole
blood, plasma and plasma fractions (human, monkeys)
** NOlHV-32950-08 Blood compatible poly-electrolytes
IONS, POLYIONS, POLYANIONS
POlHL-063 14-17 0048 Immunologic mechanisms In
cardiovascular disease - Pathogenesis of glomerulonephritis
(rats, mice)
POlHL-20948-02 0003 Molecular basis of cholesterol
metabolism - LDL pathway in vivo (human, rats, guinea
pigs)
IRA (IMMUNOREGUIATORY ALPHA GLOBULIN)
SEE IMMUNOLOGY, IMMUNOREGUUTORY ALPHA GLOBULIN
IRON
SEE ALSO ALBUMINS, CONALBUMIN
SEE ALSO HEME
SEE ALSO HEMOPROTEINS
SEE ALSO METALLOPROTEINS, FERREDOXIN
SEE ALSO MnALLOPROTEINS, FERRITIN
SEE ALSO METALLOPROTEINS, HEMERYTHRIN
SEE ALSO METALLOPROTEINS, TRANSFERRIN
SEE ALSO NUTRITION, DIETARY CONSTITUENTS, DIETARY IRON
R01HL-08299-16 Molecular biology of hemerythrin and
hemocyanin (invertebrates)
ROlHL-13157-09 Molecular oxygen carriers-Synthesis,
structure, bonding
ROlHL-13237-09 Erythrocytes during early development
(human, animals)
ROlHL-13412-17 Synthetic oxygen carriers
POlHL-16251-06 0008 Membrane-bound enzymes In heart
and other tissues - Iron-sulfur centers and phospholipids
modulation of succinate dehydrogenase
ROlHL-17794-03 Chelating agents as blood substitutes
** ROlHL-20996-02 Structural and reactivity of Iron and
cobalt complexes
ROlHL-21170-01
transferrin
ROlHL-2 146 1-01
hemoproteins
ROlHL-23 120-01
Molecular structure of human serum
Heme group protein interactions in
Chelating agents as blood substitutes
IRON, FEROXAAAINE-DEFEROXAMINE
** ROlHL-19898-03 Desferrioxamine therapy in thalassemia
(dogs, rats, children)
** ROlHL-19946-03 Reduction of iron overload in
thalassemia (children, rabbits, dogs, monkeys)
** R01HL-19961-03 Management of hemosiderosis in
thalassemia (children, adults)
** R01HL-20000-03 Iron overload in homozygous beta
thalassemia (human)
ROlHL-20016-03 Chelator development for thalassemia
(human, mice, rats, dogs, monkeys)
IRON-BINDING BETA 1 -GLOBULIN (SERUM)
SEE METALLOPROTEINS, TRANSFERRIN
IRON CHELATION THERAPY
SEE ALSO NUTRITION, DIETARY CONSTITUENTS, DIETARY IRON
** ROIHL- 17844-04 Artificial blood substitutes -02-binding
iron chelates (human, mammals)
** ROlHL-19898-03 Desferrioxamine therapy in thalassemia
(dogs, rats, children)
** ROlHL-19946-03 Reduction of iron overload in
thalassemia (children, rabbits, dogs, monkeys)
" ROIHL' 1996 1-03 Management of hemosiderosis in
thalassemia (children, adults)
** R01HL-20000-03 Iron overload in homozygous beta
thalassemia (human)
** ROlHL-200 16-03 Chelator development for thalassemia
(human, mice, rats, dogs, monkeys)
" ROlHL-20141-02 Biochemical approaches to management
of iron overload (human, sheep, dogs)
IRON CYANIDES
SEE ALSO OXIDOREOUCTASES, 0-LACTATE DEHYDROGENASE
POlHL-12157-11 0051 Functions and mechanisms of cell
membrane ion transport - Electron transport in the red cell
membrane (human, guinea pigs)
ROlHL-16236-04 Detailed characteristics of coronary blood
flow (horses, dogs, calves)
ROIHL- 17828-04 Kinetic studies of hemerythrin reactions
(marine worms)
IRON CYANIDES, SODIUM NITROFERRICYANIDE
POlHL-06285-18 0154 Cardiovascular-respiratory
physiology and biochemistry - Function and viability of
critically Ischemic myocardium (dogs)
POlHL-06308-18 0011 Mechanisms and therapy of
circulatory disease - Blood flow and electrical dysfunction
in ventricular arrhythmia (human)
POlHL-06835-17 0053 Cardiovascular disease ■
Vasodilating drugs (human)
ROlHL-07139-17 Cardiodynamics and metabolism of
congestive failure (human, dogs)
POlHL-1 1310-12 0056 Mechanisms of cardiovascular
disease - Cardiac output response to blood pressure
reduction in infants (human)
POlHL-11310-12 0058 Mechanisms of cardiovascular
disease - Dynamic response to vasodilating agents
postoperatively (human)
POlHL-1 1310-12 0062 Mechanisms of cardiovascular
disease - Myocardial depressant factor in postoperative
cardiac dysfunction (human, dogs)
POlHL-11310-12 0065 Mechanisms of cardiovascular
disease - Algorithms for arterial pressure by automatic
vasoactive agents control (human)
POlHL-1 1678-11 0059 Cardiovascular dynamics and their
control - Basic hemodynamics (dogs, rats)
ROlHL-12322-10 Extrinsic factors influencing myocardial
performance (dogs, swine)
ROlHL-12777-09
(dogs, human)
ROlHL-12827-08
Mechanisms in cardiac performance
Regulation of sodium excretion (dogs,
rats)
ROlHL-14127-16 Methemoglobinemia and antihypertensive
drugs (cats, mice, rats)
POlHL-14388-07 0185 Regulation of the circulation in
pathological states ■ Reflex control of venous tone (human,
rabbits, dogs)
ROlHL-14644-05 Optimization diastolic augmentation and
systolic sink (dogs)
ROlHL-18190-03 Myocardial blood flow in acute
myocardial infarction (human, dogs)
R01HL18537-04 Regional blood flow after acute
myocardial injury (dogs)
ROlHL-19089-03
(human, dogs)
R01HL19937-02
Diastolic properties of the left ventricle
Vasodilators in experimental myocardial
infarction (dogs)
ROlHL-20598-03 The coronary vascular response to
ischemia (dogs, pigs)
R23HL-22309-01 Cardiovascular pharmacodynamics In
immature dogs
ROlHL-22836-01 The spontaneously hypertensive kidney
(rats)
IRON DEFICIENCY ANEMIA CLASSICAL
SEE BLOOD AND RE DISORDERS, ANEMIA HYPOCHROMIC
MICROCYTIC
(contd)
'Excludes routine mathodotogy OR coven only general projicti which preclude Indexing at the specific level.
"Orientad ilgnlficantly to abova lubject.
M Grant has subprojects describing specific research aspects.
See Appendix for Investigator's name and grant number.
IRO
IRON DISORDERS AND IMBALANCES
SEE ALSO BLOOD AND RE DISORDERS. ANEMIA
SIDEROBUSTIC
SEE ALSO IRON CHEUIION THERAPY
SEE ALSO NUTRITION, DIETARY CONSTITUENTS. DIETARY IRON
** ROIHL'06242 18 Kinttic studits ol blood (human)
ROIHL llSll 10 Structure ol territin and its role in iron
metabolism (horse, rats, human)
** ROIHI 18712 03 Iron deticiency hyperlipidemia in
development (rats)
IRON DISORDERS AND IMBALANCES,
HEMOSIDEROSIS
SEE ALSO METABOLIC DISORDERS INBORN,
HEMOCHROMATOSIS
** ROIHL 1989803 Desferrioxamine therapy in thalassemia
(dogs. rats, children)
ROIHL'1994603 Reduction of iron overload in
thalassemia (children, rabbits, dogs, monkeys'
** ROIHL 1996103 Management o( hemosideros.i in
thalassemia (children, adults)
ROIHL 2000003 Iron overload in homozygous beta
thalassemia (human)
ROIHL 2001603 Chelator development for thalassemia
(human, mice, rats. dogs, monkeys)
IRON DISORDERS AND IMBALANCES, IRON
STORAGE DISORDERS (GENERAL)
SEE ALSO IRON DISORDERS AND IMBALANCES,
HEMOSIDEROSIS
SEE ALSO METABOLIC DISORDERS INB0RI4,
HEMOCHROMATOSIS
** ROlHL'20141-02 Biochemical approaches to management
of iron overload (human, sheep, dogs)
IRON EXCESS (GENERAL)
SEE IRON DISORDERS AND IMBAUNCES, IRON STORAGE
DISORDERS (GENERAL)
IRON METABOLISM
SEE ALSO NUTRITION, DIETARY CONSTITUENTS, DIETARY IRON
** R01HL0624218 Kinetic studies of blood (human)
ROlHL-07449'17 Formation and survival of red blood cells
(human)
** ROlHL-11511-10 Structure of ferritin and its role in iron
metabolism (horse, rats, human)
" R01HL18012-04 Cellular defects in nocturnal
hemoglobinuria (human)
R01HL-18ei9-03 Transferrin iron binding and transport
properties (chicken, rabbit, human)
ROlHL-18712-03 Iron deficiencyhyperlipidemla in
development (rats)
** R01HL1949103 Mechanism of iron storage and
mobilization by ferritin (horse)
ROlHL-19633-02 Pathogenesis and pharmacology of lung
fibrosis (rats, rabbits)
IRON OXIDES
ROlHL'17543-03 0001 Magnetic tracers for diagnosis of
lung disease - Chronic, interstitial lung disease (human,
rabbits)
ROlHL-17543-03 0002 Magnetic tracers for diagnosis of
lung disease - Magnetite as an index of asbestos exposure
(human)
ROlHL-17543-03 0003 Magnetic tracers for diagnosis of
lung disease - Occupationally accumulated magnetite for
diagnosis of lung disease (human)
ROlHL-17543-03 0004 Magnetic tracers for diagnosis of
lung disease - Magnetite retention, distribution, relaxation
rate, viscosity (rabbits)
R23HL' 19584-01 Alveolar macrophage responses to toxic
particle exposure (guinea pigs, human)
IRON STORAGE DISORDERS
SEE IRON DISORDERS AND IMBALANCES, IRON STORAGE
DISORDERS (GENERAL)
IRRIGATION (BODY)
SEE THERAPY, UVAGE
IRRITATION AND IRRITANTS
SEE DISEASES, PATHOLOGIC PROCESSES, IRRITATION
(IRRITANTS)
ISCHEMIA
SEE CARDIOVASCUUR DISORDERS, ISCHEMIA
ISCHEMIC BONE NECROSIS
SEE SKELETAL DISORDERS, BONE NECROSIS ISCHEMIC
ISOAUOANTIBODIES
SEE TISSUE COMPATIBILITY-TRANSPLANT, ISOALLOANTIBODIES
ISOAUOANTIGENS
SEE TISSUE COMPATIBILITY-TRANSPLANT, ISOALLOANTIGENS
ISOAUOIMMUNITY
SEE TISSUE COMPATIBILITY-TRANSPUNT. ISOALLOIMMUNITY
ISOANTIBODIES
SEE TISSUE COMPATIBILITY-TRANSPUNT, ISOALLOANTIBODIES
ISOANTIOENS
SEE TiSSUE COMPATIBILITY-TRANSPUNT, ISOALLOANTIGENS
31 1
ISOCITRATE DEHYDROGENASE
SEE OXIOOREDUCIASfS, ISOCIIRAIE DEHYDROGENASE
ISOCYANATES
SEE CYANAIES. ISOCYANATES
ISOELECTRIC ANALYSIS, CONDENSATION
SEE PHYSICAL SEPARATION. ELECTROfOCUSING*
ISOELECTRIC FOCUSING, FRACTIONATION,
SEPARATION
SEE PHYSICAL SEPARATION, ELECTROFOCUSING*
ISOELECTRIC POINT
SEE ACIDS BASES. ISOELECTRIC POINT
ISOENZYMES
SEE ENZYMES, ISOENZYMES
ISOHEMAGGLUTININS
SEE BLOOD GROUPS ISOANTIBODIES
ISOIMMUNITY
SEE TISSUE COMPATIBILITY-TRANSPLANT, ISOALLOIMMUNITY
ISOLATION, SOCIAL, PSYCHOSOCIAL
SEE PSYCHOSOCIAL ISOLATION-DEPRIVATION
ISOLATION PERFUSION
SEE DOSAGE AND ROUTE, ISOLATION-PERFUSION
ISOLOGOUS TRANSPLANTATION
SEE TISSUE COMPATIBILITY-TRANSPUNT, TRANSPUNTATION
HOMOLOGOUS
ISOMERASES
ROlHL-20996-02 Structural and reactivity of iron and
cobalt complexes
ROlHL-22946-01 Prostaglandins, platelet aggregation and
vasoactivity (human, rats, rabbits)
ISOMERS
SEE CHEMICAL STRUCTURE, ISOMERS
ISOMORPHOUS SUBSTITUTION
SEE CHEMICAL REACTIONS, SUBSTITUTION, ISOMORPHOUS
ISONIAZID
SEE AZO COMPOUNDS. HYDRAZINES, ISONIAZID
ISONICOTINIC ACID
SEE PYRIDINE CARBOXYLIC ACIDS, ISONICOTINIC ACID
ISOPRENOIDS
SEE ALKENES. ISOPRENOIDS
ISOPROTERENOL
SEE PHENYULKYUMINES, CATECHOUMINES,
ISOPROTERENOL
ISOPTIN
SEE PHENYULKYUMINES, VERAPAMIL
ISOQUINOLINES
SEE QUINOLINES, ISOQUINOLINES
ISOSORBIDE DINITRATE
SEE SUGAR ALCOHOLS, HEXITOLS, ISOSORBIDE DINITRATE
ISOSTERIC SITES
SEE CHEMICAL REACTION SITES, ISOSTERIC SITES
ISOTOPE EFFECTS (EXCLUDING RADIATION
EFFECTS)
** ROlHL-22567-01 Validation of a cholesterol absorption
method in man
ISOTOPE EFFECTS, RADIOISOTOPES
SEE RADIOISOTOPES
ISOTOPE LABELED, RADIOISOTOPES
SEE RADIOISOTOPES
ISOTOPE LABELED, STABLE CARBON
R01HL-14680-07 Specific enrichment of myoglobins for
carbon 13 NMR (catacea)
P60HL-17269-04 0016 National heart and blood vessel
research and demonstration center - New analytical
methodology for atherosclerosis studies
PeOHL-17269-04 0046 National heart and blood vessel
research and demonstration center - Nuclear magnetic
resonance laboratory
ISOTOPE (STABLE, LABELED) DIAGNOSIS
SEE RADIOISOTOPE (NUCLEAR) MEDICINE, STABLE (UBELED)
ISOTOPE DIAGNOSIS
ISUPREL
SEE PHENYULKYUMINES, CATECHOUMINES,
ISOPROTERENOL
JACKBEAN AGGLUTININ (LECTIN)
SEE PUNTS PROTEINS, LECTINS. CONCANAVALIN A
JAPANESE
SEE SOCIAL GROUPS, ETHNIC, ASIANS, JAPANESE
JAPANESE-AMERICANS
SEE SOCIAL GROUPS, ETHNIC, AMERICANS, JAPANESE-
AMERICANS
KID
JAPANESE B ENCEPHALITIS VIRUS
SEE VIRUSES. ARBOVIRUSES B. JAf'ANFSE B ENCEPHALITIS
VIRUS
JAUNDICE
SEE ALSO BLOOD AND RE DISORDERS. ANEMIA HEMOLYTIC
SEE ALSO LIVER DISORDERS, HEPATITIS SERUM
SEE ALSO LIVER DISORDERS. HEPATITIS VIRAl HUMAN
ROIHL 1530807 Assays for peptides ol lipoproteins
(human)
JAUNDICE EPIDEMIC
SEE LIVER DISORDERS, HEPATITIS VIRAL HUMAN
JAUNDICE HEMOLYTIC
SEE BLOOD AND RE DISORDERS. ANEMIA HEMOLYTIC
CONGENITAL (GENERAL)
JAUNDICE HEMOLYTIC HEREDITARY (GENERAL)
SEE BLOOO AND RE DISORDERS. ANEMIA HEMOLYTIC
CONGENITAL (GENERAL)
JAUNDICE HOMOLOGOUS SERUM
SEE LIVER DISORDERS. HEPATITIS SERUM
JAUNDICE NEONATAL (TRANSIENT)
ROIHL 06221 17 Composition and structure of plasma
lipoproteins (human, turkeys, baboons)
JEJUNOCOLOSTOMY
SEE GASTROINTESTINAL SURGERY. ILEAL BYPASS-ILEECTOMY
JEJUNOILEOSTOMY
SEE GASTROINTESTINAL SURGERY. ILEAL BYPASS-ILEECTOMY
JEJUNUM
SEE GASTROINTESTINAL SYSTEM, INTESTINES, SMALL
INTESTINE, JEIUNUM
JOB SATISFACTION
SEE OCCUPATIONS, JOB SATISFACTION
JUVENILE (ANIMAL)
SEE AGE (ANIMAL), JUVENILE (POST-INFANCY TO PUBERTY)
JUVENILE (HUMAN)
SEE CHILDREN, ADOLESCENCE (12 TO 21 YRS)
JUVENILE DIABETES
SEE CARBOHYDRATES METABOLISM DISORDERS, DIABETES,
JUVENILE
JUXTAGLOMERULAR APPARATUS
SEE KIDNEY, JUXTAGLOMERUUR APPARATUS
K-CELLS
SEE BLOOD CELLS, T LYMPHOCYTES, KILLER
KALLIDIN
SEE PEPTIDES, VASOACTIVE PEPTIDES, KALLIDIN
KAUIDIN-9
SEE PEPTIDES. VASOACTIVE PEPTIDES, KALLIDIN-9
KAUIKREIN
SEE PEPTIDES. VASOACTIVE PEPTIDES, KALUKREIN
KAUIKREIN-ASSOCIATED HYPERTENSION
SEE CARDIOVASCUUR DISORDERS, HYPERTENSION
(SYSTEMIC), KININS-BRADYKININ-KALLIKREIN-
ASSOCIATED
KAUIKREIN INHIBITOR, TRASYLOL
SEE PROTEASES AND PEPTIDASES, TRASYLOL
KANAMYCIN
SEE ANTIBIOTICS. KANAMYCIN
KARYOTYPES
SEE GENETICS, KARYOTYPES
KERATOHYALIN
SEE ALBUMINOIDS. KERATOHYALIN
KET AMINE
SEE CYCLIC KETONES, CYCLOHEXANONES, KETAMINE
KETOGLUTARATE DEHYDROGENASE
SEE OXIDOREDUCTASES, OXOGLUTARATE DEHYDROGENASE
KETONE BODIES
SEE ALSO FATTY ACIDS, ACETOACETATES
SEE ALSO FATTY ACIDS, BETA-HYOROXYBUTYRIC ACID
SEE ALSO HEXOSES, GLUCONEOGENESIS
ROlHL-12085-10
(human, rats)
ROlHL-13302-09
Lipoprotein-carbohydrate metabolism
Uptake and metabolism of lipids by the
Hormonal control of lipid and lipoprotein
liver (rats)
ROlHL-15930-06
synthesis (rats)
ROIHL- 18089-04 Fatty acid metabolism in heart and its
regulation (swine, rats)
ROlHL-20388-03 Regulation of protein turnover in diabetic
heart (rat)
ROlHL-20488-03 Cholesterol metabolism in diabetic man
KETONES (SEE ALSO SPECIFICS)
ROlHL-18679-04 Synthetic protease inhibitors
tichHlM routine inathodok>o OR covtn only general pnijects which preclude Indexing at the specific level.
"Oiientad dgnlficantly to above tubject.
M Grant has subprojects describing specific research aspects.
See Appendix lor investigator's name and grant number.
KID
KIDNEY
ROlHL-01974-24 Ion-pump in the erythrocyte (rabbits,
guinea pigs)
ROlHL-0772315. Reflex control of vascular capacitance in
shock
P01HL-144H-07 0014 Environmental influences on
cardiorespiratory and cellular functions ■ Temperature and
acid-base status in tissues, cells, and subcellular system
POlHL-14414-07 0016 Environmental influences on
cardiorespiratory and cellular functions - Effects of
pressure on membrane and cellular function (human,
rabbits)
ROlHL-15447-06 Vascular role of prostaglandin and cyclic
nucleotides (rats)
** ROlHL-18019-04 The endocrine kidney in hypertension
(mice)
ROlHL-18199-03 Effects of ions on vascular reactivity
POlHL-19737-02 0007 Cellular and molecular aspects of
respiratory physiology Average oxygen tension of tissue
using radioisotopes (dogs)
ROlHL-20278-02 Cellular mechanisms of renin secretion
(rats)
R01HL-20594-02 Renal enzymes that regulate blood
pressure (human, rats)
ROlHL-20787-02 Thromboxanes and prostaglandins-
Biochemical pharmacology (rabbits, human)
KIDNEY, GLOMERULUS
ROlHL-01803-23 0001 Arteriosclerosis, glomerulonephritis,
rheumatic fever • Poststreptococcal glomerulonephritis
(rabbit)
" POlHL-03174-23 0005 Mechanisms of acute vascular
reaction to injury - Renal small vessel didease-Cell and
matrix response (human, mice)
** ROlHL-04300-20 Fine structure of diseased glomeruli
(human, rats, dogs)
** POlHL-06314-17 0063 Immunologic mechanisms in
cardiovascular disease - Glomerular cells in tissue culture
(human)
POlHL-06314-17 0066 Immunologic mechanisms in
cardiovascular disease - Sensitization, cell-mediated
cytotoxicity, role of lymphocytes (human, mice)
ROlHL-10980-11 Ultrastructural renal pathology (human,
rats)
ROlHL-13694-08 Capillary basement membrane in
cardiovascular disease (human, rats)
** ROIHL-14914-06 Autoregulation of glomerular filtration
rate (rats)
** ROlHL-19316-03 Study of glomerular permeability (fish,
turtle, frog, chordates, Crustacea)
ROlHL-19463-02 Pathophysiology of acute renal failure
(rats)
KIDNEY, JUXTAGLOMERULAR APPARATUS
ROlHL-02493-22 Kidney function in experimental heart
failure (dogs, rats)
P01HL-14388-07 0188 Regulation of the circulation in
pathological states - Renin-angiotensin system in the sheep
fetus
** ROlHL-18340-04 Electron microscopy of the
juxtaglomerular apparatus (rats)
KIDNEY, RENAL CORTEX
ROlHL-02835-21 Renal transport carrier for organic
compounds (dogs, rats)
ROlHL-02986-21 Zonal renal change with potassium
deficiency (rats, human)
R23HL-2 1247-02 Purification of renal renin (human)
KIDNEY, RENAL MEDULLA
** ROlHL-02986-21 Zonal renal change with potassium
deficiency (rats, human)
** POlHL-06285-18 0200 Cardiovascular-respiratory
physiology and biochemistry - Medullary counter-current
system (animals)
** ROlHL-07835-17 Experimental hypertension and renal
circulation (rats, rabbits)
** POlHL-1 1678-11 0064 Cardiovascular dynamics and their
control - Renal medulla-Control of renal hemodynamics,
electrolyte excretion (dogs)
** ROlHL-19287-03 The antihypertensive function of the
renal medulla (human, rats, rabbits)
ROlHL-22563-02 Prostaglandins, the kidney and
hypertension (rats)
KIDNEY, RENAL TUBULES
ROlHL-02986-21 Zonal renal change with potassium
deficiency (rats, human)
** ROlHL-13929-06 Single nephron response to chronic
obstruction (frogs, rats)
ROlHL-14133-08 Intrarenal regulation of sodium
reabsorption (dogs, hamsters, rats)
P01HL14388-07 0191 Regulation of the circulation In
pathological states - Regulation of chloride transport in
epithelial membranes (turtles)
POlHL-14388-07 0192 Regulation of the circulation in
pathological states - Renal tubular secretion of magnesium
(rats)
ROlHL-16603-05 Human and experimental renal diseases
(animals)
POlHL-17871-04 0013 Kidney, sodium, cardiac output,
arterioles and hypertension - Perfusion pressure and renal
sodium excretion (rats)
ROlHL-18097-04 Pathogenesis of acute renal failure (rats)
312
KIDNEY, RENAL TUBULES, MACULA
ROlHL-02493-22 Kidney function in experimental heart
failure (dogs, rats)
ROlHL-106 12-13 0020 Humoral factors in heart failure
and hypertension - The control of renin release in the dog
ROIHL 22390-01 Effect of chloride on renin (rats, dogs)
KIDNEY CALCULI
SEE KIDNEY DISORDERS, KIDNEY CALCULI
KIDNEY CELLS
POlHL-08214-15 0023 Chemical and biological properties
of lipids - Lipids in microorganisms and cell cultures
(hamsters, mosquitoes)
ROlHL-10567-12 Erythropoietin -Immunoassay and
characterization (dogs)
ROlHL-15567-05 Cardiovascular phosphoinosltide
metabolism (rats)
ROlHL-16320-05 Vasoactive peptides which stimulate
smooth muscles (rats, human)
KIDNEY CIRCULATION
SEE ALSO KIDNEY, GLOMERULUS
SEE ALSO KIDNEY-CIRCUUTORY DISORDERS
SEE ALSO KIDNEY SURGERY, KIDNEY REVASCULARIZATION
ROlHL-02334-23 Micropuncture study of kidney function
(rats, animals)
ROlHL-02493-22 Kidney function in experimental heart
failure (dogs, rats)
" ROlHL-03181-21 0028 Hemodynamics as applied to
surgical problems - Extra-renal factors in the hypertension
of coarctation (dog)
POlHL-0631417 0047 Immunologic mechanisms in
cardiovascular disease Role of intravascular coagulation
(human, animals)
** POlHL-063 14-17 0065 Immunologic mechanisms in
cardiovascular disease • Transplantation biology and
clinical transplantation
POlHL-06370-17 0001 Cardiopulmonary and renal
pathology research center - The humoral and cellular
mechanisms of allograft rejection (monkeys)
** POlHL-06664-17 0010 Cardiopulmonary function in
remediable vascular disease - Ischemia and acute renal
failure (rats)
" ROlHL-07835-17 Experimental hypertension and renal
circulation (rats, rabbits)
ROlHL-08570-15 Pharmacologic and reflex influence on
vascular tone (dogs, rabbits)
POlHL-08682-15 0027 Regulation of the cardiovascular
system - Cardiac mechanoreceptors-Reflex regulation of
renal function (dogs)
ROlHL-10182-13 Circulatory function and electrolytic
metabolism (dogs, human)
ROlHL-10384-13 Blood flow and nucleotide metabolism
(animals)
POlHL-10436-13 0014 A multidisciplinary study of
congenital heart disease - Cardiovascular pharmacology
(dog)
** ROlHL-10612-13 0018 Humoral factors in heart failure
and hypertension - The pathogenesis of experimental renal
hypertension (dogs, rabbits, rats)
ROlHL-1061213 0020 Humoral factors in heart failure
and hypertension - The control of renin release in the dog
** ROlHL-10942-09 Study of genetic hypertension in rats
** POlHL-11678-11 Cardiovascular dynamics and their
control
** POlHL-11678-11 0051 Cardiovascular dynamics and their
control - Transient glomerular filtration dynamics (dogs)
** POlHL-11678-11 0058 Cardiovascular dynamics and their
control - Overall control of the circulation-Computer
analysis
** POlHL-11678-11 0063 Cardiovascular dynamics and their
control - Renin-angiotensin system-Control of renal
hemodynamics, electrolyte excretion
** POlHL-11678-11 0064 Cardiovascular dynamics and their
control - Renal medulla-Control of renal hemodynamics,
electrolyte excretion (dogs)
** POlHL-11678-11 0067 Cardiovascular dynamics and their
control - Angiotension II, sodium excretion and renal
hemodynamics (dogs)
ROlHL-12607-10 Dynamics of pulsatile blood flow (human,
dogs, rats)
** ROlHL-12677-10 Surgical physiologic studies of isolated
kidneys (dogs, rats)
ROlHL-12827-08 Regulation of sodium excretion (dogs,
rats)
ROlHL-13323-08 Intrarenal pressure and renal function
(human, dogs)
ROlHL-13427-09 Neural control of blood volume (monkeys,
dogs)
ROlHL-13634-08 Renal hypertension in pregnancy (sheep)
ROlHL-13917-20 Secretion and effects of adrenal
hormones (human, rabbits, sheep)
ROlHL-13929-06 Single nephron response to chronic
obstruction (frogs, rats)
** ROlHL-14148-07 0008 The regional circulations - Renal
circulation in hypertensive patients (also dogs)
P50HL-14192-08 0005 Specialized center of research in
hypertension - New techniques for recognition of
renovascular hypertension (human, dogs)
** P50HL14192-08 0008 Specialized center of research in
hypertension - New radiographic methods-Recognition of
renovascular hypertension (human, dog)
R01HL-I4306-07
(dogs)
POlHL-14388-07 0190
pathological states
aldosterone (rats)
POlHL-14388-07 0191
pathological states
KID
Quantification of arterial pressure control
Regulation of the circulation in
Mechanisms of the renal actions of
Regulation of the circulation in
Regulation of chloride transport in
epithelial membranes (turtles)
POlHL-14388-07 0225 Regulation of the circulation in
pathological states - Release of renal prostaglandins by
saluretic-diuretic agents (dogs)
R01HL-I4944-07 Renal vascular reactivity in hypertensive
Genesis of hypertension in renal disease
patient
ROlHL-15124-05
(human, dogs)
ROlHL-15416-06 Cardiovascular control in normal and
disease states (dogs, baboons)
ROlHL-16489-04 Renal prostaglandins-Synthesis and
function (human, dogs, rats)
ROlHL-16496-04 Prostaglandins and renin experimental
hypertension (rabbits)
ROlHL-1651104 Sympathetic afferent activity of cardiac
origin (dogs, monkeys)
ROIHL 16648-16 Integrated control of cardiovascular
activity (cats)
R01HL-16658-05 Intrarenal regulation of sodium
reabsorption
P01HL16910-05 0006 Regulation of the peripheral
circulation - Regulation of blood flow distribution (baboons,
dogs)
POlHL-16910-05 0007 Regulation of the peripheral
circulation - CNS -Behavioral influences on circulation
(baboons)
ROlHL-17366-05 Mechanisms in the production of renal
hypertension (rabbits, dogs)
R01HL-U458-04 Renal control of sodium excretion (rats)
ROlHL-17781-03 Hypertension, kidney disease and renal
lymph (dogs, rats)
«l POlHL-17871-04 Kidney, sodium, cardiac output, arterioles
and hypertension
■* POlHL-17871-04 0009 Kidney, sodium, cardiac output,
arterioles and hypertension - Kidney, sodium, cardiac
output, arterioles and hypertension
POlHL-17871-04 0010 Kidney, sodium, cardiac output,
arterioles and hypertension - Renal prostaglandins
metabolism in hypertension (rats, dogs)
** ROlHL-17902-04 Mammalian renal microcirculation
(hamsters)
" P50HL18318-03 0007 Pathogenesis and complications of
hypertension - Humoral factors and renal function in
experimental hypertension (rats)
P50HL-18318-03 0013 Pathogenesis and complications of
hypertension - Humoral factors and renal function in
human hypertension
** ROlHL-18340-04 Electron microscopy of the
juxtaglomerular apparatus (rats)
** ROlHL-18426-04 Regulation of renal hemodynamics (dogs)
ROlHL-18579-03 Vasoactive hormones and blood pressure
regulation (dogs, rats, rabbits)
** R01HL-18845-04 Regulation of renal circulation and salt
excretion (rats, dogs)
ROlHL-18875-03 Angiotension, prostaglandins, pressure
and the kidney (rats)
ROlHL-18882-02 Hormones in hypertension (human)
ROlHL-18948-03 Pulseless flow and circulatory assistance
(dogs, calves)
POlHL-18974-03 0006 Experimental neurogenic
hypertension program - Model of sustained arterial
hypertension (cats)
ROlHL-18995-04 Cardiovascular determinants of
catecholamine release (dogs)
** ROlHL-19057-03 Catecholamines and cyclic AMP in
cardiovascular system (rats, dogs)
ROlHL-19134-04 Angiotensin, prostaglandins, adrenergic
interactions (rats, rabbits)
ROlHL-19229-02 Prostaglandins and hypertension (human,
rats, dogs, rabbits)
ROlHL-19428-03 Role of angiotensin sensitivity in renin
release (human)
R01HL-19539-03
arteritis (rabbits)
ROlHL-19791-02
vessels
R01HL-I9825-02
hypertension (dogs)
** ROlHL-20572-02 0003 Hemodynamic relations to
metabolism in hypertension - Cardiac output and organ
blood flow in hypertension (rats)
ROlHL-20768-02 Mechanisms of circulatory regulation in
heart failure (guinea pigs)
ROlHL-20861-01 Cardio-respiratory-renal stress reactions
(dogs)
** ROlHL-20864-01 Postnatal maturation of cardiovascular
regulatory system (minipig)
M ROlHL-20895-03 Cineangiographic studies of
cardiovascular system
ROlHL-20895-03 0001 Cineangiographic studies of
cardiovascular system - Videodensitometry and valvular
regurgitation (human, dogs)
ROlHL-20895-03 0002 Cineangiographic studies of
cardiovascular system - Coronary disease-Regional
myocardial blood flow (human, dog)
(contd)
Pathology of hypertensive-associated
Ultrasonic monitoring visceral blood
Renin-volume interactions in coarctation
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Oriented sisnificantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
KID
ROIHL 2089S03 0007 C(naangio|iaphic studies ol
cardiovascular system Determinants ol collateial
formation (dogs, hamsters)
ROIHL 2089503 0010 Cineangiograpliic studies ot
cardiovascular system Cortical necrosis and acute renal
tailure (human, dogs. rats, rabbits)
ROIHL 21094 01 Arterial baroreceptors and renal function
(dogs)
R01HL212I00I
surgery (human)
ROIHL'2130801 Prostaglandins and local control ot the
circulation (rats, dogs)
R23HL 21382 02 ttlect of pressure on renal blood flov»
and function (dogs)
Autonomic control of renal function
Acute renal failure following cardiac
Experimental renal arterial hypertension
R01HL2143602
(cats)
ROIHL 2206902
(dogs)
ROIHL 2217201 Hypotension, renal ischemia and effect ot
mannitol (dogs, rats)
ROlHL-2224401 Cardiopulmonary bypass and the
vascular endothelium (dogs)
ROIHL 22306 01 Renal catecholamines- Pathophysiology
ot hypertension (dogs)
ROlHL-2241801 Neural control of cardiorespiratory
function (cats)
R23HL-22438 01
(rats)
ROIHL 2248201
excretion (dogs)
ROlHL-2250601
hypertensions
ROlHL-2261701
(sheep)
R23HL-2272801
ROlHL-23312-01
The etiology of genetic hypertension
Circulatory hemodynamics and sodium
Hemodynamics of the clinical
Angiotensin, hypertension and the CNS
Neural control of renin secretion (dogs)
Hemodynamics and vasoactivity in renal
hypertension (human, dogs)
** R01HL-23602-01 Physiology of renin, aldosterone and
prostaglandin (human, rats, dogs)
KIDNEY CIRCULATION, RENAL ARTERY
ROlHL-04457-20 Cellular aspects of active transport (fish,
rabbits, anurans. turtles)
R01HL10612-13 0018 Humoral factors in heart tailure
and hypertension - The pathogenesis of experimental renal
hypertension (dogs, rabbits, rats)
POlHL-1167811 0063 Cardiovascular dynamics and their
control ■ Renin-angiotensin system -Control of renal
hemodynamics, electrolyte excretion
P50HL-17648-04 0013 Study ot ischemic heart disease -
Fate of bypassed and bypassing vessels (dogs)
ROlHL-20787-02 Thromboxanes and prostaglandins -
Biochemical pharmacology (rabbits, human)
ROlHL-2167301 Pathophysiology of venous changes in
hypertension (rats, rabbits, human, dogs)
KIDNEY CIRCULATION, RENAL VEINS
P50HL-17648-04 0013 Study of ischemic heart disease -
Fate of bypassed and bypassing vessels (dogs)
ROlHL-20787-02 Thromboxanes and prostaglandins -
Biochemical pharmacology (rabbits, human)
KIDNEY-CIRCULATORY DISORDERS
SEE ALSO KIDNEY DISORDERS, GLOMERULONEPHRITIS
SEE ALSO KIDNEY DISORDERS. NEPHROSCLEROSIS
** ROlHL-00340-29 Electrolyte disturbance in cardio-renal
disease (human, dogs, rats)
** POlHL-03174-23 0005 Mechanisms of acute vascular
reaction to injury - Renal small vessel didease-Cell and
matrix response (human, mice)
ROlHL-03181-21 0020 Hemodynamics as applied to
surgical problems - Blood flow measurement-Cardiac
output and regional flows (dogs)
M POlHL-06314-17 Immunologic mechanisms in
cardiovascular disease
POlHL-06314-17 0062 Immunologic mechanisms in
cardiovascular disease - Immunologic renal vascular
disease (human, animals)
ROlHL-12677-10 Surgical physiologic studies of isolated
kidneys (dogs, rats)
P60HL-1516007 0016 Center for sickle cell disease -
Kinin and plasmin system in sickle cell disease (human)
** ROlHL-21272-02 Sodium homeostasis and renal
prostaglandins (dogs)
KIDNEY-CIRCULATORY DISORDERS, RENAL
ARTERY OBSTRUCTION
R01HL01015-27 Hypertension and left ventricular
hypertrophy (dogs)
POlHL-08682-15 0026 Regulation ol the cardiovascular
system - Hypertension-High renin vs low renin (dog)
** POlHL-1 1678-11 0060 Cardiovascular dynamics and their
control - Salt and water balance in one kidney Goldblatt
hypertension (rat)
ROlHL-13595-08 Renin and vascular hyper-reactivity in
hypertension (human, rats)
** ROlHL-13929-06 Single nephron response to chronic
obstruction (frogs, rats)
P50HL-14159-08 0020 Specialized center of research in
hypertension - Renin-mineralocorticoid system in
hypertension (human, rat. dog)
313
PSOHL 14192 08 0001 Specialiied center ol research in
hypertension Surgical and medical treatment ol
renovascular hypertension (human)
" P50HL 14192 08 0002 Specialiied center ol research in
hypertension Hypertensive patients with renal artery
stenosis
P50HI 1419208 0003 Specialiied center ol research in
hypertension Prostaglandins as mediators ol renin
secretion (human, dog)
P50HL 14192 08 0005 Specialiied center ol research in
hypertension New techniques tor recognition of
renovascular hypertension (human, dogs)
ROIHL 14306 07 Quantification ol arterial pressure control
(dogs)
ROIHL 16489-04 Renal prostaglandins Synthesis and
function (human, dogs, rats)
** ROIHL 16496 04 Prostaglandins and renin experimental
hypertension (rabbits)
POIHL-18S75 03 0007 Mechanisms of vascular changes
in hypertension Microscopy ol hypertensive arterial lesions
(rats)
ROIHL 19112 03 Atherosclerosis studies (monkeys)
ROlHL-19209-03 Role of ADH in experimental renal
hypertension (dogs, rats)
ROlHL-19246 03 Regression of cardiac hypertrophy-
Myocardial and renal (human)
P50HL 1936202 0010 A/S SCOR -Atherosclerosis in
nonhuman primates - Antihypertensive therapy-
Atherogenesis in experimental hypertension (baboon)
** R01HL21092-02 Factors other than renin in renal
hypertension (rats)
ROlHL-221 72-01 Hypotension, renal ischemia and effect of
mannitol (dogs, rats)
ROlHL-22667-01 Mechanisms of baroreceptor adaptation
in hypertension (dogs)
ROlHL-233 12-01 Hemodynamics and vasoactivity in renal
hypertension (human, dogs)
ROlHL-23602-01 Physiology of renin, aldosterone and
prostaglandin (human, rats, dogs)
KIDNEY-CIRCULATORY DISORDERS, RENAL
HYPERTENSION
SEE ALSO ADRENAL GUNDS DISORDERS. ADRENAL
HYPERTENSION
SEE ALSO PEPTIDES. VASOACTIVE PEPTIDES. ANGIOTENSIN
SEE ALSO PREGNANCY TOXEMIAS AND HYPERTENSION
** R01HL-01015-27 Hypertension and left ventricular
hypertrophy (dogs)
POlHL-03174 23 0013 Mechanisms of acute vascular
reaction to injury - Surface morphology of the aorta in
normal and injured states (rats, rabbits)
ROlHL-03303-21 Factors regulating electrolyte excretion by
the kidney (human, dogs)
** ROlHL-04300-20 Fine structure of diseased glomeruli
(human, rats, dogs)
POlHL-06314-17 0065 Immunologic mechanisms in
cardiovascular disease - Transplantation biology and
clinical transplantation
ROlHL-06736-18 Biogenic-mechanical factors in
microcirculation (rats, gerbils)
POlHL-06835-17 0030 Cardiovascular disease - Synthesis
and pharmacology of angiotensin antagonists (rats, cats)
POlHL-06835-17 0031 Cardiovascular disease - Synthesis
of potent antagonist of pressor action of angiotensin II
(animals)
" POlHL-06835-17 0034 Cardiovascular disease - Studies
of phospholipase A2 in serum (rats, dogs)
POlHL-06835-17 0038 Cardiovascular disease - Effect of
chronic administration of angiotensin antagonist (rats)
** POlHL-06835-17 0039 Cardiovascular disease -
Reversibility of vascular changes in renal hypertension
(rats)
** POlHL-06835-17 0040 Cardiovascular disease - Benign
and malignant phase of renal hypertension (dogs)
** POlHL-06835-17 0041 Cardiovascular disease - Cardiac
performance in rats with renal hypertension
** POlHL-06835-17 0042 Cardiovascular disease -
Myocardial hypertrophy due to renal hypertension (rats)
** POlHL-06835-17 0045 Cardiovascular disease - Pressure-
volume-renin relationship in human hypertension
** POlHL-06835-17 0060 Cardiovascular disease ■
Ventricular performance experimental models of arterial
hypertension (rats, dogs)
** ROlHL-0783517 Experimental hypertension and renal
circulation (rats, rabbits)
M POlHL-08682-15 Regulation of the cardiovascular system
POlHL-08682-15 0005 Regulation of the cardiovascular
system - Smooth muscle and mechanical properties of
blood vessels (dogs, human)
** POlHL-08682-15 0026 Regulation of the cardiovascular
system - Hypertension -High renin vs low renin (dog)
** POlHL-08682-15 0027 Regulation of the cardiovascular
system - Cardiac mechanoreccptors -Reflex regulation of
renal function (dogs)
ROlHL-08977-14 Quantitation of flow and solute flux in
microvessels (cats, rats)
** R01HL099 11-12 Hormonal and dietary modification of
NaCl toxicity (rats) mice)
M ROlHL-10612-13 Humoral factors in heart failure and
hypertension
** ROlHL-10612-13 0018 Humoral factors in heart failure
and hypertension The pathogenesis of experimental renal
hypertension (dogs, rabbits, rats)
M
KID
ROIHL 10612 13 0019 Humoral factort in heart failure
and hypsrtension Pathogenesis ol hypertention in the
spontaneous hypertensive rat
ROIHL 10881 13 Structure and function of
microcirculation (hamsters, rats, cats, dogs)
ROIHL 11046 12 Renin, angiotensin, steroids, ions and
blood pressure (human, sheep, rabbits)
POIHL 11678 II Cardiovascular dynamics and their
control
POIHI 11678 II 0001 Cardiovascular dynamics and their
control Body fluid volumes in the genesis of hypertension
(rats, dogs)
POIHL 11678 11 0027 Cardiovascular dynamics and their
control Vasopressin and thirst in control ol body lluid
volumes and osmolality (dogs)
POIHL 11678 11 0034 Cardiovascular dynamics and their
control Renal function curves in intact dogs
PniHL 11678 11 0040 Cardiovascular dynamics and their
control Control of plasma potassium concentration (dogs)
POIHL 11678 11 0046 Cardiovascular dynamics and their
control Regulation of aldosterone secretion and related
factors (dogs)
POIHL 11678-11 0051 Cardiovascular dynamics and their
control Transient glomerular filtration dynamics (dogs)
POIHL 11678-11 0060 Cardiovascular dynamics and their
control Salt and water balance in one kidney Goldblatt
hypertension (rat)
POlHL-1 1678-11 0063 Cardiovascular dynamics and their
control ■ Renin-angiotensin system Control of renal
hemodynamics, electrolyte excretion
POlHL-1 1678-11 0064 Cardiovascular dynamics and their
control • Renal medulla -Control of renal hemodynamics,
electrolyte excretion (dogs)
ROlHL-12415-10 Evaluation of left ventricular function
(dogs, rabbits)
ROlHL-12614-09 Microcirculatory control mechanisms and
hypertension (bats, rats)
ROIHL 12766-09 Structure-function relation of blood
vessels (rats, monkeys)
ROIHL- 12990-09 Control of antidiuretic hormone secretion
and metabolism (dogs, rats, rabbits)
ROlHL-13634-08 Renal hypertension in pregnancy (sheep)
ROlHL-13936-06 Microvascular responses in hypertension
(human, rats)
ROlHL-14133-08 Intrarenal regulation of sodium
reabsorption (dogs, hamsters, rats)
P50HL-14159-08 0008 Specialized center of research in
hypertension Renal function and sodium metabolism in
hypertension (rats, human, rabbits)
P50HL-14159-08 0018 Specialized center of research in
hypertension ■ Sympathetic nervous system in hypertension
(rats)
P50HL-14159-08 0020 Specialized center of research in
hypertension - Renin-mineralocorticoid system in
hypertension (human, rat, dog)
P50HL-14159-08 0021 Specialized center of research in
hypertension - Genetic studies of the physiology of
hypertension (human, rats)
P50HL- 14 159-08 0024 Specialized center ol research in
hypertension - Core resources (clinical, animal models)
P50HL-14192-08 Specialized center of research in
hypertension
* P50HL-14192-08 0001 Specialized center of research in
hypertension - Surgical and medical treatment of
renovascular hypertension (human)
* P50HL-14192-08 0002 Specialized center of research in
hypertension - Hypertensive patients with renal artery
stenosis
* P50HL-14192-08 0003 Specialized center of research in
hypertension - Prostaglandins as mediators ol renin
secretion (human, dog)
P50HL-14192-08 0004 Specialized center ol research in
hypertension - Isolation and characterization of pure renin
(swine, rats, human, rabbits)
* P50HL-14192-08 0005 Specialized center of research in
hypertension - New techniques for recognition of
renovascular hypertension (human, dogs)
* P50HL-14192-08 0008 Specialized center of research in
hypertension - New radiographic methods-Recognition of
renovascular hypertension (human, dog)
* ROlHL-14306-07 Quantification of arterial pressure control
(dogs)
ROlHL-14397-07 Hypertension-Angiotensin and
prostaglandin pharmacology (animals)
'♦ R01HL-14913-06
(rats)
■* ROlHL-14944-07
Hypertension-Genetic influence of kidney
Renal vascular reactivity in hypertensive
Genesis of hypertension in renal disease
patient
ROlHL-15124-05
(human, dogs)
ROlHL-15528-05 Renin kinetics in hypertensive and
uremic plasma (human, dogs)
ROlHL-1583706 Renin and cardiac hypertrophy in
hypertension (rats)
ROlHL-15839-05 Physiological role of isorenin and
kallikrein (animals)
ROlHL-16489-04 Renal prostaglandins-Synthesis and
function (human, dogs, rats)
ROlHL-16496-04 Prostaglandins and renin experimental
hypertension (rabbits)
ROlHL-16603-05 Human and experimental renal diseases
(animals)
(contd)
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
**Orieiited significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
KID
ROlHL-16658-05 Intrarenal regulation of sodium
reabsorptlon
ROlHL-17243-05 Cause of chronic experimental renal
hypertension (dogs, rabbits)
ROIHLI 7364-04 'Big renin'-Biochemical and clinical
studies (human)
R01HL173ee-05 Mechanisms in the production of renal
hypertension (rabbits, dogs)
ROlHL-17458-04 Renal control of sodium excretion (rats)
** ROlHL-17781-03 Hypertension, kidney disease and renal
lymph (dogs, rats)
M POlHL-17871-04 Kidney, sodium, cardiac output, arterioles
and hypertension
** POlHL-17871-04 0009 Kidney, sodium, cardiac output,
arterioles and hypertension - Kidney, sodium, cardiac
output, arterioles and hypertension
** POlHL-17871-04 0010 Kidney, sodium, cardiac output,
arterioles and hypertension - Renal prostaglandins
metabolism in hypertension (rats, dogs)
** POlHL-17871-04 0013 Kidney, sodium, cardiac output,
arterioles and hypertension Perfusion pressure and renal
sodium excretion (rats)
ROlHL-1790204 Mammalian renal microcirculation
(hamsters)
** ROlHL-17947-04 Experimental renal and neurogenic
hypertension (human, animals)
** ROlHL-18019-04 The endocrine kidney in hypertension
(mice)
ROlHL-18027-03 New vasoactive factors and their role in
hypertension (human, dogs, rats)
P50HL-18318-03 0002 Pathogenesis and complications of
hypertension - Core experimental animal facility (rats,
rabbits)
P50HL-18318-03 0007 Pathogenesis and complications of
hypertension - Humoral factors and renal function in
experimental hypertension (rats)
P50HL-18318-03 0019 Pathogenesis and complications of
hypertension - Renin-angiotensin system in blood pressure
regulation (human, rat, dog)
M P50HL18323-04 SCOR hypertension center
** P50HL-18323-04 0012 SCOR hypertension center - Renin
as a risk factor (human)
** P50HL-18323-04 0037 SCOR hypertension center •
Adrenocortical factors in childhood hypertension
P50HL-18323-04 0042 SCOR hypertension center - Blood
viscosity and blood volume in hypertensive disease
(human, dog)
P50HL18323-04 0044 SCOR hypertension center -
Angiotensin blockade to identify angiotensin II factor in
hypertension (human)
M POlHL-18575-03 Mechanisms of vascular changes in
hypertension
** POlHL-1857503 0001 Mechanisms of vascular changes
in hypertension - Arteries and resistance vessels in
hypertension (pigs, rats)
** P01HI.-1857503 0002 Mechanisms of vascular changes
in hypertension - Endocrines, electrolytes, and
hemodynamics in hypertension (pigs)
** POlHL-18575-03 0005 Mechanisms of vascular changes
in hypertension - Renin synthesis in normotensive and
hypertensive pigs (also rats, dogs)
** POlHL-18575-03 0006 Mechanisms of vascular changes
in hypertension - Evaluation of arterial compliance in
hypertension (human, pigs)
** POlHL-18575-03 0007 Mechanisms of vascular changes
in hypertension - Microscopy of hypertensive arterial lesions
(rats)
•* P01HL18575-03 0009 Mechanisms of vascular changes
in hypertension - Administrative core
** POlHL-18575-03 0010 Mechanisms of vascular changes
in hypertension - Hypertensive pig Core
** POlHL-18575-03 0011 Mechanisms of vascular changes
in hypertension - Chemistry laboratory core facility
*• P01HL18575-03 0012 Mechanisms of vascular changes
in hypertension - Anatomy core facility
** POlHL-18575-03 0013 Mechanisms of vascular changes
in hypertension • Biostatistical core
** ROlHL-18579 03 Vasoactive hormones and blood pressure
regulation (dogs, rats, rabbits)
ROlHL-18624-03 Study of kinins in hypertension and other
diseases (human)
** ROlHL-18845-04 Regulation of renal circulation and salt
excretion (rats, dogs)
** ROlHL-18862-02 Thirst and its contribution to edema
(dogs)
R01HL18875-03 Angiotension, prostaglandins, pressure
and the kidney (rats)
** ROlHL-18893-03 Mechanism of angiotensin action-Role of
receptor (rats)
** ROlHL-18923-02 Steroid-induced hyperlipidemia and
hypertension (human, rats)
ROlHL-18976-03 Blood pressure control-Relation to
behavioral stress (human, dog)
** ROlHL-191 12-03 Atherosclerosis studies (monkeys)
** ROlHI.19134-04 Angiotensin, prostaglandins, adrenergic
interactions (rats, rabbits)
** ROlHL-19144-03 Contraceptive steroids and experimental
hypertension (rats)
** ROlHL-19209-03 Role of ADH in experimental renal
hypertension (dogs, rats)
314
'* POlHL-19242-02 0008 Study of vascular smooth muscle -
NE release in and reactivity of vascular smooth muscle
(rats)
ROlHL-19287-03 The antihypertensive function of the
renal medulla (human, rats, rabbits)
" P50HL-1936202 0010 A/S SCOR -Atherosclerosis in
nonhuman primates - Antihypertensive therapy -
Atherogenesis in experimental hypertension (baboon)
ROlHL-19374-03 Pharmacology of kinins in cardiovascular
disease (rats, rabbits)
" ROlHL-19428-03 Role of angiotensin sensitivity in renin
release (human)
** ROlHL-19467-03 Regulation of blood pressure (rats, dogs)
ROlHL-195 17-03 Synthesis of inhibitors for the study of
renal renin (dogs, monkeys)
" ROlHL-19539-03 Pathology of hypertensive-associated
arteritis (rabbits)
** ROlHL-19825-02 Renin-volume interactions in coarctation
hypertension (dogs)
** ROlHL-20201-01 Hypertension and vascular steroid
receptors (rats)
ROlHL-20455-03 Role of systemic hypertension on diabetic
retinopathy (human)
** ROlHL-20594-02 Renal enzymes that regulate blood
pressure (human, rats)
** ROlHL-20604-03 Sympathectomy-Cardiovascular and
molecular pharmacology (animals)
ROlHL-206 78-02 Cardiovascular adaptation to stress in
disease states (dogs)
** ROlHL-21071-02 Mechanisms of hypertension in
coarctation of the aorta (dog)
** ROlHL-21092-02 Factors other than renin in renal
hypertension (rats)
** ROlHL-21103-01 Parametric mechanical studies of
hypertensive arteries (dogs, rats)
R23HL-2 11 67-02 The electrophysiology of cardiac
hypertrophy (rats)
ROlHL-21394-02 Pulmonary anglotensin-converting enzyme
(rabbits)
R23HL-21462-02 Mechanical interactions between ventricle
arteries (dogs)
ROlHL-21525-02 Effect of cations, anions and water upon
blood vessels (dogs, rats)
** ROlHL-2185101 Cerebral microcirculation in experimental
hypertension (cats, rabbits)
** ROlHL-2187201 Myocardial perfusion in the hypertrophied
heart (dogs)
** ROlHL-21877-01 Iso-renins in the hypertensive rat
** R23HL-21901-01 Hypertension, microvascular control and
exercise (rats)
** ROlHL-21993-01 Hypertensive hypertrophy-Effects of
cardiac mechanics (rats)
" ROlHL-22069-02 Experimental renal arterial hypertension
(dogs)
** ROlHL-222 16-02 Vascular mechanisms in renal
hypertension (dogs)
** ROlHL-22261-01 Compliance of fluid spaces in advancing
hypertension (rats)
** ROlHL-22563-02 Prostaglandins, the kidney and
hypertension (rats)
** ROlHL-22667-01 Mechanisms of baroreceptor adaptation
in hypertension (dogs)
** R23HL-22745-01 Vascular mechanics and structure in
hypertension (miniature swine)
" ROlHL-233 12-01 Hemodynamics and vasoactivity in renal
hypertension (human, dogs)
** ROlHL-23600-01 Ions, water, and hypertension (human,
dogs, rats)
ROlHL-23602-01 Physiology of renin, aldosterone and
prostaglandin (human, rats, dogs)
ROlHL-23603-01 Morphogenesis of hypertensive vascular
disease (rats)
KIDNEY-CIRCULATORY DISORDERS, RENAL
ISCHEMIA AND HYPOXIA
M POIHL-06664-17 Cardiopulmonary function in remediable
vascular disease
** POlHL-06664-17 0010 Cardiopulmonary function in
remediable vascular disease ■ Ischemia and acute renal
failure (rats)
** POlHL-06664-17 0036 Cardiopulmonary function in
remediable vascular disease - In vitro studies on the
mechanism of ischemic damage to cells (rabbits)
** POlHL-06664-17 0037 Cardiopulmonary function in
remediable vascular disease - Salt and water balance of
cells and tissues (rabbits)
** POlHL-06835-17 0061 Cardiovascular disease - Studies
in renal physiology (human, rats, dogs)
ROlHL-13323-08 Intrarenal pressure and renal function
(human, dogs)
ROlHL-14397-07 Hypertension -Angiotensin and
prostaglandin pharmacology (animals)
ROlHL-17781-03 Hypertension, kidney disease and renal
lymph (dogs, rats)
ROlHL-19673-03 Surgical aspects of shock and hypoxia
(dogs, monkeys, rats)
ROlHL-19791-02 Ultrasonic monitoring visceral blood
vessels
ROlHL-20895-03 0001 Cineangiographic studies of
cardiovascular system - Videodensitometry and valvular
regurgitation (human, dogs)
KID
** ROlHL-20895-03 0007 Cineangiographic studies of
cardiovascular system - Determinants of collateral
formation (dogs, hamsters)
** ROlHL-22172-01 Hypotension, renal ischemia and effect of
mannitol (dogs, rats)
KIDNEY-CIRCULATORY DISORDERS, RENOPRIVAL
HYPERTENSION
SEE ALSO KIDNEY SURGERY, NEPHRECTOMY
ROlHL-08570-15 Pharmacologic and reflex influence on
vascular tone (dogs, rabbits)
ROIHL- 15808-06 Role of angiotensinogen in hypertension
and stroke (human, rabbits)
** P50HL-18323-04 0045 SCOR hypertension center -
Laboratory programs-Prorenin (human)
KIDNEY DISORDERS
SEE ALSO CARBOHYDRATES METABOLISM DISORDERS,
DIABETIC NEPHROPATHIES
SEE ALSO CARDIOVASCUUR AND RENAL STUDY SECTION
SEE ALSO KIDNEY CIRCULATORY DISORDERS
SEE ALSO LIVER DISORDERS, HEPATORENAL SYNDROME
SEE ALSO METABOLIC DISORDERS INBORN, BARHER'S
SYNDROME
SEE ALSO METABOLIC DISORDERS (INBORN), RENAL
TUBULAR ACIDOSIS
** R01HL-02334-23 Micropuncture study of kidney function
(rats, animals)
** ROIHL 02986-21 Zonal renal change with potassium
deficiency (rats, human)
** ROlHL-04300-20 Fine structure of diseased glomeruli
(human, rats, dogs)
M POlHL-06370-17 Cardiopulmonary and renal pathology
research center
ROIHL 10980-11 Ultrastructural renal pathology (human,
rats)
R01HL-11046-12 Renin, angiotensin, steroids, ions and
blood pressure (human, sheep, rabbits)
** POlHL-1 1678-11 0058 Cardiovascular dynamics and their
control - Overall control of the circulation-Computer
analysis
P01HL-14388-07 0191 Regulation of the circulation in
pathological states - Regulation of chloride transport in
epithelial membranes (turtles)
POlHL-14388-07 0224 Regulation of the circulation in
pathological states - Kallikrein-kinln system in hypertension
(human)
** ROlHL-14720-08 Factors governing the renal excretion of
acid (humans, rats)
ROIHL- 14944-07 Renal vascular reactivity in hypertensive
patient
** ROlHL-15 124-05 Genesis of hypertension in renal disease
(human, dogs)
P60HL-15170-05 0019 Support for center for sickle cell
anemia - Renal handling of uric acid in sickle cell anemia
(human)
" ROlHL-15810-06 Electrolyte physiology and respiratory
acid-base (dogs)
** ROlHL-16603-05 Human and experimental renal diseases
(animals)
ROlHL-17364-04 'Big renin'-Biochemical and clinical
studies (human)
POlHL-18574-03 0006 Lipoprotein methodology and
biomedical applications - Lipoprotein transformation,
lipolytic enzymes, diet and lipid lowering agents
ROlHL-19366-03 Renal Starting forces in experimental
conditions (rats, rabbits)
ROlHL-2 11 59-02 Pathophysiological effects of hypoxia
(rats)
ROlHL-2 1644-01 Fibronectin and related giycoproteins
(human, rodents)
** ROlHL-22939-01 Human kinin and fibrinolytic systems
and renal disease (human)
KIDNEY DISORDERS, ANURIA
SEE ALSO KIDNEY DISORDERS, RENAL FAILURE
ROlHL-02334-23 Micropuncture study of kidney function
(rats, animals)
KIDNEY DISORDERS, ANURIA, OLIGURIA
SEE ALSO KIDNEY FUNCTION, ANTIDIURESIS
ROlHL-10182-13 Circulatory function and electrolytic
metabolism (dogs, human)
KIDNEY DISORDERS, GLOMERULONEPHRITIS
SEE ALSO CARBOHYDRATES METABOLISM DISORDERS,
DIABETIC NEPHROPATHIES
SEE ALSO DISEASES, SYNDROMES NOT LISTED ELSEWHERE,
GOODPASTURE'S SYNDROME
SEE ALSO KIDNEY DISORDERS, NEPHROTIC SYNDROME
M ROlHL-01803-23 Arteriosclerosis, glomerulonephritis,
rheumatic fever
** ROlHL-01803-23 0001 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Poststreptococcal glomerulonephritis
(rabbit)
** ROlHL-01803-23 0018 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Fetal immunization in pathogenesis of
glomerulonephritis in adult (rabbit)
ROlHL-02334-23 Micropuncture study of kidney function
(rats, animals)
** POlHL-03174-23 0005 Mechanisms of acute vascular
reaction to injury - Renal small vessel didease-Cell and
matrix response (human, mice)
(contd)
•Excludes routine methodotogy OR cuvers only general projects which preclude indexing at the specific level.
**Oraflted slinificantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investieator's name and grant number.
KID
The cell sulace ol streptococci (rats.
ROIHL 0391920
human)
ROIHL'04300'20 Fin* sliuctuie ol diseased glomeruli
(human, lats, dO(s)
Immunologic mechanisms in
Pathogenesis ol glomeiulonephiitis
POIHI 06314 17 0048
caidiovasculai disease
(lats. mice)
POIHL 06314 17 0061
cardiovascular disease
Immunologic mechanisms in
Role ol viruses in cardiovascular
and renal disease (human, mice)
POIHL 063 14 17 0062 Immunologic mechanisms in
cardiovasculai disease Immunologic renal vascular
disease (human, animals)
ROIHL 07836 17 Experimental hypertension and renal
circulation (rats, rabbits)
ROIHL 10980 11
rats)
Ultrastructural renal pathology (human.
Genesis ol hypertension in renal disease
Human and experimental renal diseases
•* R01HL151240b
(human, dogs)
•• ROIHL 1660305
(animals)
ROIHL 1936603 Renal Starling lorces in experimental
conditions (rats, rabbits)
ROIHL 2021802 Fibrinogen catabolism and Intravascular
coagulation (human)
KIDNEY DISORDERS, HYDRONEPHROSIS
ROlHL-20787-02 Thromboxanes and prostaglandins -
Biochemical pharmacology (rabbits, human)
KIDNEY DISORDERS, KIDNEY CALCULI
ROIHLI 1901-12 0018 Elfects of metabolic surgery on
the hyperlipidemias - Jejunoileal bypass-Postoperative
complications (human)
KIDNEY DISORDERS, KIDNEY NECROSIS
ROIHL 02334 23 Micropuncture study of kidney function
(rats, animals)
POlHL-0666417 0037 Cardiopulmonary function in
remediable vascular disease - Salt and water balance of
cells and tissues (rabbits)
** ROlHL-2089503 0010 Cineangiographic studies of
cardiovascular system - Cortical necrosis and acute renal
failure (human, dogs, rats, rabbits)
KIDNEY DISORDERS, NEPHRITIS
SEE ALSO KIDNEY DISORDERS, GLOMERULONEPHRITIS
SEE ALSO KIDNEY DISORDERS, PYELONEPHRITIS
P01HL0631417 0048
cardiovascular disease
(rats, mice)
P01HL06314-17 0062
cardiovascular disease
Immunologic mechanisms in
Pathogenesis of glomerulonephritis
Immunologic mechanisms in
Immunologic renal vascular
disease (human, animals)
ROlHL-14914-06 Autoregulation of glomerular filtration
rate (rats)
P01HL16411-04 0001 Blood systems in coagulation and
vessel disease - Molecular studies of the role of
complement in blood coagulation (human, rabbits)
ROIHL- 16490-04 Structural basis of nephron filtration
(rats, rabbits)
ROlHL-17706-04 Psychosocial hypertension,
catecholamines and drugs (mice)
KIDNEY DISORDERS, NEPHRITIS INTERSTITIAL
ROlHL-19366-03 Renal Starling forces in experimental
conditions (rats, rabbits)
KIDNEY DISORDERS, NEPHROSCLEROSIS
SEE ALSO CARBOHYDRATES METABOLISM DISORDERS.
DIABETIC NEPHROPATHIES
POlHL-0897414 0028 Natural and experimental
atherosclerosis • Geographic pathology of atherosclerosis
and coronary heart disease (human)
ROlHL-17754-03 Pathogenesis and prevention of
hypertension sequelae (rats)
KIDNEY DISORDERS, NEPHROSIS
R01HL02965-22 Metabolism of plasma lipoproteins (rats,
chickens, human)
** R01HL16490-04 Structural basis of nephron filtration
(rats, rabbits)
ROlHL-22051-01 Role of angiotensin II in vasopressin
release (human)
KIDNEY DISORDERS, NEPHROSIS LOWER
NEPHRON
ROlHL-02334-23 Micropuncture study of kidney function
(rats, animals)
** ROlHL-18097-04 Pathogenesis of acute renal failure (rats)
** ROlHL-19463-02 Pathophysiology of acute renal failure
(rats)
KIDNEY DISORDERS, NEPHROTIC SYNDROME
** ROlHL-00759-29 Regulation of electrolyte and acid base
equilibrium (dogs)
ROlHL-02955-22 Metabolism of plasma lipoproteins (rats,
chickens, human)
Immunologic mechanisms in
• Pathogenesis of glomerulonephritis
P01HL0631417 0048
cardiovascular disease
(rats, mice)
POlHL-06314-17 0054
cardiovascular disease
rats, mice)
ROlHL-17458-04 Renal control of sodium excretion (rats)
Immunologic mechanisms in
Diabetic vascular disease (human.
315
ROIHL 1916803 Biosynthesis ol plasms lipoprotein (rats,
rabbits)
ROIHt 19366 03 Renal Starling lorces in experimenlal
conditions (rats, rabbits)
" ROIHL 1942803 Role of angiotensin sensitivity in renin
release (human)
** ROIHL 21498-02 Pathophysiology of edema (rats, cats)
ROIHL 226 18 01 Role of apolipoproteins in
hypertriglyceridemia (human)
POIHL 2261901 0012 Cellular mechanisms of heart
failure Apolipoproteins in hypertriglyceridemia (human)
POlHL-22633-01 0001 Cellular and molecular biology of
lipoprotein metabolism Secretion of lipoproteins by the
perfused liver (rats, rabbits)
** R01HL2301501 Mechanisms of hypo-oncotic pulmonary
edema (human, dogs)
KIDNEY DISORDERS, PYELONEPHRITIS
ROlHL-07835 17 Experimental hypertension and renal
circulation (rats, rabbits)
ROlHL-14914-06 Autoregulation of glomerular filtration
rate (rats)
ROIHL 19366 03 Renal Starling lorces in experimental
conditions (rats, rabbits)
KIDNEY DISORDERS, RENAL FAILURE
SEE ALSO KIDNEY DISORDERS, NEPHROSIS LOWER NEPHRON
SEE ALSO KIDNEY DISORDERS, UREMIA
SEE ALSO KIDNEY PROSTHESIS, ARTIFICIAL KIDNEY
** R01HL00759 29 Regulation ol electrolyte and acid base
equilibrium (dogs)
** POlHL-031 74-23 0005 Mechanisms of acute vascular
reaction to injury - Renal small vessel didease-Cell and
matrix response (human, mice)
POlHL-06314-17 0065 Immunologic mechanisms in
cardiovascular disease Transplantation biology and
clinical transplantation
** POlHL-06664-17 0010 Cardiopulmonary function in
remediable vascular disease - Ischemia and acute renal
failure (rats)
ROlHL-07835-17 Experimental hypertension and renal
circulation (rats, rabbits)
** POlHL-11310-12 0084 Mechanisms of cardiovascular
disease - Evaluation of cardiac function in chronic renal
failure (human)
R01HL-12677-10 Surgical physiologic studies of isolated
kidneys (dogs, rats)
** ROlHL-13323-08 Intrarenal pressure and renal function
(human, dogs)
ROlHL-13929-06 Single nephron response to chronic
obstruction (frogs, rats)
R01HL14148-07 0002 The regional circulations -
Catecholamine metabolism in subtypes of hypertension
(human, animals)
ROlHL-14914-06 Autoregulation of glomerular filtration
rate (rats)
** ROlHL-15528-05 Renin kinetics in hypertensive and
uremic plasma (human, dogs)
ROlHL-16219-05 Mechanisms of atherogenesis in chronic
uremia (human, rats)
R01HL17458-04 Renal control of sodium excretion (rats)
** ROlHL-17781-03 Hypertension, kidney disease and renal
lymph (dogs, rats)
ROlHL-17902-04 Mammalian renal microcirculation
(hamsters)
P50HL-183 18-03 0019 Pathogenesis and complications of
hypertension • Renin-angiotensin system in blood pressure
regulation (human, rat, dog)
ROIHL 18923-02 Steroid-induced hyperlipidemia and
hypertension (human, rats)
** ROIHL-19428-03 Role of angiotensin sensitivity in renin
release (human)
** ROlHL-20895-03 0010 Cineangiographic studies of
cardiovascular system - Cortical necrosis and acute renal
failure (human, dogs, rats, rabbits)
** ROlHL-212 10-01 Acute renal failure following cardiac
surgery (human)
ROlHL-22172-01 Hypotension, renal ischemia and effect of
mannitol (dogs, rats)
R23HL-22882 01 Modulation by disease of effect of
furosemide in man
ROlHL-23602-01 Physiology of renin, aldosterone and
prostaglandin (human, rats, dogs)
KIDNEY DISORDERS, RENAL HYPERTROPHY
POlHL-06285-18 0178 Cardiovascular-respiratory
physiology and biochemistry - Biochemical regulation of
hypertrophy (rats, rabbits)
POlHL-11678-11 0017 Cardiovascular dynamics and their
control - Overall control of circulation-Mathematical
analyses
** ROlHL-22482-01 Circulatory hemodynamics and sodium
excretion (dogs)
KIDNEY DISORDERS, UREMIA
SEE ALSO KIDNEY DISORDERS, RENAL FAILURE
ROlKL-00340-29 Electrolyte disturbance in cardio-renal
disease (human, dogs, rats)
POIHL-08899-14 0014 Tolerance to respiratory gases in
health and disease - Cellular and renal responses to
hypercapnia and hypocapnia (dogs)
** POlHL-11678-11 Cardiovascular dynamics and their
control
KID
POIHI 116/8 II 001/ Cardlovitcultr dynsmici tnd their
control Overall control ol circulation Mathematical
analyses
ROIHL 12839 09 flow, transport and membrane
phenomena in blood (human)
** ROIHL 14092 07 Homeostalic regulation ol plasma choline
(rats. dogs, chickens)
** ROIHL 1552805 Renin kinetics in hypertensive and
uremic plasma (human, dogs)
** ROIHL 1621905 Mechanisms of atherogenesis in chronic
uremia (human, rats)
ROIHI 17706 04 Psychosocial hypertension,
catecholamines and drugs (mice)
KIDNEY DISORDERS CHEMOTHERAPY
SEE ALSO KIDNEY PHARMACOLOGY
P01HL06664 17 0010 Cardiopulmonary function in
remediable vascular disease - Ischemia and acute renal
failure (rats)
ROlHL-13634 08 Renal hypertension in pregnancy (sheep)
ROIHL 17364 04 Big renin' Biochemical and clinical
studies (human)
POIHL 17871 04 0009 Kidney, sodium, cardiac output.
arterioles and hypertension - Kidney, sodium, cardiac
output, arterioles and hypertension
" ROlHL-18097-04 Pathogenesis of acute renal failure (rats)
ROlHL-1857903 Vasoactive hormones and blood pressure
regulation (dogs, rats, rabbits)
ROIHL 21105-02 Organ specilic drugs -Cardiovascular and
renal effects (dogs)
R23HL 2288201 Modulation by disease of effect of
furosemide in man
KIDNEY DISORDERS DIAGNOSIS (INCL EXAMS)*
SEE ALSO KIDNEY VISUALIZATION*
ROlHL-04300-20 Fine structure of diseased glomeruli
(human, rats, dogs)
POlHL-06664-17 0010 Cardiopulmonary function in
remediable vascular disease - Ischemia and acute renal
failure (rats)
** ROlHL-10980 11 Ultrastructural renal pathology (human,
rats)
ROIHLI 1046-12 Renin, angiotensin, steroids, ions and
blood pressure (human, sheep, rabbits)
ROlHL-15528-05 Renin kinetics in hypertensive and
uremic plasma (human, dogs)
** ROlHL-17364-04 Big renin' -Biochemical and clinical
studies (human)
ROlHL-19517-03 Synthesis of inhibitors for the study of
renal renin (dogs, monkeys)
ROlHL-1982502 Renin-volume interactions in coarctation
hypertension (dogs)
ROlHL-20895-03 0001 Cineangiographic studies of
cardiovascular system - Videodensitometiy and valvular
regurgitation (human, dogs)
** ROlHL-22667-01 Mechanisms of baroreceptor adaptation
in hypertension (dogs)
KIDNEY EXAMINATIONS
SEE KIDNEY DISORDERS DIAGNOSIS (INCL E)(AMS)*
KIDNEY FUNCTION
** ROlHL-02334-23 Micropuncture study of kidney function
(rats, animals)
** ROlHL-02493-22 Kidney function in experimental heart
failure (dogs, rats)
ROlHL-02835-21 Renal transport carrier for organic
compounds (dogs, rats)
ROlHL-06143 18 Response of the totally denervated heart
to exercise (dogs)
** POlHL-08682-15 0027 Regulation of the cardiovascular
system - Cardiac mechanoreceptors -Reflex regulation of
renal function (dogs)
POlHL-0880515 0006 Regulation of ventilation and
pulmonary circulation - Adaptation of lungfish -Estivation
** POlHL-08899-14 0021 Tolerance to respiratory gases in
health and disease - Renal oxygen toxicity (dogs)
** ROlHL-09154-14 Central control of distribution of organ
blood flow (monkeys)
ROlHL-10612-13 0018 Humoral factors in heart failure
and hypertension - The pathogenesis of experimental renal
hypertension (dogs, rabbits, rats)
POlHL-11678-11 Cardiovascular dynamics and their
control
POlHL-1167811 0017 Cardiovascular dynamics and their
control ■ Overall control of circulation -Mathematical
analyses
** ROlHL-12677-10 Surgical physiologic studies of isolated
kidneys (dogs, rats)
** R01HL13323-08 Intrarenal pressure and renal function
(human, dogs)
POlHL-13330-08 0059 Mechanical circulatory support -
Physiologic evaluation of circulatory assistance (cattle)
R01HL13623-08 Atrial receptors (dogs)
** ROlHL-13917-20 Secretion and effects of adrenal
hormones (human, rabbits, sheep)
ROlHL-13929-06 Single nephron response to chronic
obstruction (frogs, rats)
R01HL-14092-07 Homeostatic regulation of plasma choline
(rats, dogs, chickens)
ROlHL-1430507 Quantification of arterial pressure control
(dogs)
(contd)
'Excludes routine methodology OR cavers only general projects which preclude indexing at the specific level.
**0nented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
I'llTl ■ lIll'lfMlll
KID
316
KID
POlHL-14388-07 0188 Regulation of the circulation in
pathological states - Renin-angiotensin system In the sheep
fetus
POlHL-14414-07 0015 Environmental influences on
cardiorespiratory and cellular functions - Control of the
cardiovascular system (dogs)
ROlHL-14560-07 Hypertension produced by sympathetic
dysfunction (human, rats)
R01HL14720-08 Factors governing the renal excretion of
acid (humans, rats)
R01HL17352-03 Physiological regulation during chronic
hyperthermia (sheep)
** ROlHL-1784704 Cardiovascular and renal functions of
marmots
M P01HL17871-04 Kidney, sodium, cardiac output, arterioles
and hypertension
P01HL18575-03 0002 Mechanisms of vascular changes
in hypertension ■ Endocrines, electrolytes, and
hemodynamics in hypertension (pigs)
ROlHL-18875-03 Angiotension, prostaglandins, pressure
and the kidney (rats)
ROlHL-18948-03 Pulseless flow and circulatorv assistance
(dogs, calves)
ROlHL-19246-03 Regression of cardiac hypertrophy-
Myocardial and renal (human)
R01HL19316-03 Study of glomerular permeability (fish,
turtle, frog, chordates. Crustacea)
ROlHL-20895-03 0010 Cineangiographic studies of
cardiovascular system - Cortical necrosis and acute renal
failure (human, dogs, rats, rabbits)
ROlHL-2 1094-01 Arterial baroreccptors and renal function
(dogs)
R01HL21159-02 Pathophysiological effects of hypoxia
(rats)
** ROlHL-21210-01 Acute renal failure following cardiac
surgery (human)
** ROlHL-21351-02 Renal and vascular control by
sympathetic ganglia (animals)
ROlHL-2143502 Control, cardiovascular and renal effects
of potassium (dogs)
** ROlHL-21436-02 Autonomic control of renal function
(cats)
ROlHL-22306-01 Renal catecholamines- Pathophysiology
of hypertension (dogs)
ROlHL-2259401 Reflex control of the circulation in heart
failure (dogs)
KIDNEY FUNCTION, ANTIDIURESIS
SEE ALSO KIDNEY DISORDERS, ANURIA, OLIGURIA
ROlHL-20861-01 Cardio-respiratory-renal stress reactions
(dogs)
KIDNEY FUNCTION, ANTIDIURETICS
** POlHL-12738-10 0129 Physiologic pharmacology and its
clinical applications - Receptor specificities and
metabolism of vasopressin analogs
ROlHL-20176-02 Biochemistry and genetics of salt
hypertension (rats)
KIDNEY FUNCTION, DIURESIS
SEE ALSO CARBOHYDRATES METABOLISM DISORDERS,
DIABETES
SEE ALSO KIDNEY FUNCTION, SALURESIS
SEE ALSO METABOLIC DISORDERS (INBORN), DIABETES
INSIPIDUS
ROlHL-1091410 Renal sodium transport in experimental
aldosteronism (dogs)
** POlHL-1167811 0034 Cardiovascular dynamics and their
control - Renal function curves in intact dogs
POlHL-11678-11 0060 Cardiovascular dynamics and their
control - Salt and water balance in one kidney Goldblaft
hypertension (rat)
POlHL-1 1678-11 0064 Cardiovascular dynamics and their
control ■ Renal medulla-Control of renal hemodynamics,
electrolyte excretion (dogs)
POlHL-1 1678-11 0065 Cardiovascular dynamics and their
control • Body fluid volumes in the genesis of hypertension
(dogs)
ROlHL-12827-08 Regulation of sodium excretion (dogs,
rats)
P50HL14187-07 0005 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses - Pulmonary
hypertension and cardiac function (dogs, human)
R01HL14720-08 Factors governing the renal excretion of
acid (humans, rats)
ROlHL-17407-05 Peripheral circulation and fluid balance
(fish, mammals, human)
P50HL-18318-03 0013 Pathogenesis and complications of
hypertension Humoral factors and renal function in
human hypertension
ROlHL-18426-04 Regulation of renal hemodynamics (dogs)
KIDNEY FUNCTION, DIURETICS
ROlHL-02493-22 Kidney function in experimental heart
failure (dogs, rats)
•* POlHL-0631217 0051 Surgical cardiology - Diuretic
therapy on myocardial electrolyte composition and water
content (human)
POlHL-06835-17 0045 Cardiovascular disease ■ Pressure-
volumerenin relationship in human hypertension
POlHL-06835-17 0046 Cardiovascular disease - Renin
activity during salt depletion in essential hypertension
(human)
POlHL-06835-17 0047 Cardiovascular disease ■
Spironolactone in primary aldosteroidism (human)
PGlHL-06835-17 0049 Cardiovascular disease - Selective
hypoaldosteronism (human)
POlHL-06835-17 0059 Cardiovascular disease -
Metyrapone-induced hypertension in dog
ROlHL-12677-10 Surgical physiologic studies of isolated
kidneys (dogs, rats)
P01HL1273810 0129 Physiologic pharmacology and its
clinical applications - Receptor specificities and
metabolism of vasopressin analogs
** R01HL13634-08 Renal hypertension in pregnancy (sheep)
P01HL14388-07 0191 Regulation of the circulation in
pathological states - Regulation of chloride transport in
epithelial membranes (turtles)
** POlHL-14388-07 0225 Regulation of the circulation in
pathological states - Release of renal prostaglandins by
saluretic-diuretic agents (dogs)
ROlHL-15810-06 Electrolyte physiology and respiratory
acid-base (dogs)
ROlHL-17749-03 Adrenocortical factors in human
hypertension (human)
ROlHL-1809704 Pathogenesis of acute renal failure (rats)
** ROlHL-18185-04 Cardiac glycosides and diuretics-Role of
NaO pump (dogs)
P50HL-1832304 0043 SCOR hypertension center -
Pharmacology-Renin-aldosterone mechanisms in essential
hypertension (human)
ROlHL-18579-03 Vasoactive hormones and blood pressure
regulation (dogs, rats, rabbits)
ROlHL-187 18-04 Prostaglandin precursors and vascular
reactivity (dogs)
ROlHL-1884504 Regulation of renal circulation and salt
excretion (rats, dogs)
ROlHL-1925103 An index of sympathetic activity in
hypertension (rats)
ROlHL-19428-03 Role of angiotensin sensitivity in renin
release (human)
ROlHL-20455-03 Role of systemic hypertension on diabetic
retinopathy (human)
ROlHL-20725-02 Mechanisms and cellular functions of ion
transport
ROlHL-21 105-02 Organ specific drugs-Cardiovascular and
renal effects (dogs)
ROlHL-21272-02 Sodium homeostasis and renal
prostaglandins (dogs)
ROlHL-21274-01 Prorenin-Physiological and biochemical
analysis (human)
ROlHL-21444-02 Pulmonary mechanics during postnatal
development (human)
ROlHL-21877-01 Iso-renins in the hypertensive rat
ROlHL-22506-01 Hemodynamics of the clinical
hypertensions
** ROlHL-22911-01 Mechanism of clearance of lung edema
fluid (dogs)
ROlHL-22977-01 Role of vasoconstrictor mechanisms in
heart failure (human, dogs)
ROlHL-23201-01 Mechanisms of hypertension (human,
rats)
KIDNEY FUNCTION, GLOMERULAR FILTRATION
R01HL04457-20 Cellular aspects of active transport (fish,
rabbits, anurans, turtles)
POlHL-06285-18 0196 Cardiovascular-respiratory
physiology and biochemistry - Hormonal regulation of
sodium transport-Epithelial cell membranes (toads)
POlHL-06285-18 0197 Cardiovascular-respiratory
physiology and biochemistry - Micropcrfusion and
micropuncture of renal tubules (hamsters, desert rats)
POlHL-06314-17 0048 Immunologic mechanisms in
cardiovascular disease - Pathogenesis of glomerulonephritis
(rats, mice)
POlHL-0631417 0062 Immunologic mechanisms In
cardiovascular disease - Immunologic renal vascular
disease (human, animals)
** POlHL-063 14-17 0064 Immunologic mechanisms in
cardiovascular disease - Diabetic vascular disease (human,
rats, mice)
POlHL-06835-17 0061 Cardiovascular disease ■ Studies
in renal physiology (human, rats, dogs)
POlHL-08682-15 0027 Regulation of the cardiovascular
system - Cardiac mechanoreceptors-Reflex regulation of
renal function (dogs)
ROlHL-106 12-13 0018 Humoral factors in heart failure
and hypertension - The pathogenesis of experimental renal
hypertension (dogs, rabbits, rats)
** POlHL-11678-11 0051 Cardiovascular dynamics and their
control - Transient glomerular filtration dynamics (dogs)
** POlHL-11678-11 0063 Cardiovascular dynamics and their
control - Renin-angiotensin system-Control of renal
hemodynamics, electrolyte excretion
POlHL-11678-11 0064 Cardiovascular dynamics and their
control - Renal medulla-Control of renal hemodynamics,
electrolyte excretion (dogs)
POlHL-1 1678-11 0065 Cardiovascular dynamics and their
control - Body fluid volumes in the genesis of hypertension
(dogs)
ROIHL 12677-10 Surgical physiologic studies of isolated
kidneys (dogs, rats)
** ROlHL-12827-08 Regulation of sodium excretion (dogs,
rats)
R01HL12974-10 Tracer kinetics, flows and masses in
body organs (human, dogs)
ROlHL-13929-06 Single nephron response to chronic
obstruction (frogs, rats)
ROlHL-1413308 Intrarenal regulation of sodium
reabsorption (dogs, hamsters, rats)
ROlHL-14148-07 0008 The regional circulations - Renal
circulation in hypertensive patients (also dogs)
** ROlHL-14914-06 Autoregulation of glomerular filtration
rate (rats)
P60HL-15170-05 0019 Support for center for sickle cell
anemia - Renal handling of uric acid in sickle cell anemia
(human)
ROlHL-16320-05 Vasoactive peptides which stimulate
smooth muscles (rats, human)
ROlHL-16489-04 Renal prostaglandins-Synthesis and
function (human, dogs, rats)
** ROlHL-16490-04 Structural basis of nephron filtration
(rats, rabbits)
ROlHL-16658-05 Intrarenal regulation of sodium
reabsorption
ROlHL-17458-04 Renal control of sodium excretion (rats)
ROlHL-18097-04 Pathogenesis of acute renal failure (rats)
P50HL18318-03 0007 Pathogenesis and complications of
hypertension - Humoral factors and renal function in
experimental hypertension (rats)
P50HL-18318-03 0013 Pathogenesis and complications of
hypertension - Humoral factors and renal function in
human hypertension
** ROlHL-18426-04 Regulation of renal hemodynamics (dogs)
** ROlHL-19316-03 Study of glomerular permeability (fish,
turtle, frog, chordates, Crustacea)
R01HL19463-02 Pathophysiology of acute renal failure
(rats)
ROlHL-19825-02 Renin-volume interactions in coarctation
hypertension (dogs)
ROlHL-2 12 10-01 Acute renal failure following cardiac
surgery (human)
ROlHL-21272-02 Sodium homeostasis and renal
prostaglandins (dogs)
R23HL-21382-02 Effect of pressure on renal blood flow
and function (dogs)
ROlHL-2143602 Autonomic control of renal function
(cats)
R23HL-22728-01 Neural control of renin secretion (dogs)
** ROlHL-22836-01 The spontaneously hypertensive kidney
(rats)
KIDNEY FUNCTION, RENAL TUBULAR
TRANSPORT
ROlHL-00340-29 Electrolyte disturbance In cardio-renal
disease (human, dogs, rats)
ROlHL-00759-29 Regulation of electrolyte and acid base
equilibrium (dogs)
** ROlHL-02334-23 Micropuncture study of kidney function
(rats, animals)
ROlHL-02493-22 Kidney function in experimental heart
failure (dogs, rats)
** ROlHL-02835-21 Renal transport carrier for organic
compounds (dogs, rats)
ROlHL-04457-20 Cellular aspects of active transport (fish,
rabbits, anurans. turtles)
P01HL06285-18 0196 Cardiovascular-respiratory
physiology and biochemistry - Hormonal regulation of
sodium transport-Epithelial cell membranes (toads)
** POlHL-06285-18 0197 Cardiovascular-respiratory
physiology and biochemistry - Microperfusion and
micropuncture of renal tubules (hamsters, desert rats)
** P01HL06285-18 0198 Cardiovascular-respiratory
physiology and biochemistry - Renal tubular secretion of
hydrogen ion (animals)
** POlHL-06285-18 0199 Cardiovascular-respiratory
physiology and biochemistry - Renal tubular reabsorption of
sodium chloride (hamsters, rabbits)
** POlHL-0628518 0200 Cardiovascular-respiratory
physiology and biochemistry - Medullary counter-current
system (animals)
** ROlHL-1091410 Renal sodium transport in experimental
aldosteronism (dogs)
ROlHL-13323-08 Intrarenal pressure and renal function
(human, dogs)
** ROlHL-14092-07 Homeostatic regulation of plasma choline
(rats, dogs, chickens)
** R01HL14133-08 Intrarenal regulation of sodium
reabsorption (dogs, hamsters, rats)
** P50HL-14159-08 0008 Specialized center of research in
hypertension - Renal function and sodium metabolism in
hypertension (rats, human, rabbits)
P01HL14388-07 0191 Regulation of the circulation in
pathological states - Regulation of chloride transport in
epithelial membranes (turtles)
** POlHL-14388-07 0192 Regulation of the circulation in
pathological states • Renal tubular secretion of magnesium
(rats)
POlHL-14414-07 0014 Environmental influences on
cardiorespiratory and cellular functions - Temperature and
acid-base status in tissues, cells, and subcellular system
P01HL14414-07 0016 Environmental influences on
cardiorespiratory and cellular functions ■ Effects of
pressure on membrane and cellular function (human,
rabbits)
ROlHL-14720-08 Factors governing the renal excretion of
acid (humans, rats)
(contd)
•Excludes routine methodotogy OR covers only general projects which preclude indexing at the specific level.
**Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
-.SS-:
KID
Intraienal regulation of sodium
Circulatory hemodynamics and sodium
The spontaneously hypertensive kidney
•* P60HL 1517005 0019 Support lor center loi sickle cell
anemia Renal handlini ot uric acid in sickle cell anemid
(human)
ROIHL 15810 06 Electrolyte physiology and respiratory
acid base (dogs)
•• P60HL 16005 05 0019 Comprehensive sickle cell center
Handling ot uric acid in sickle cell anemia (human)
ROIHL 16320 05 Vasoactive peptides which stimulate
smooth muscles (rats, human)
** ROIHL 16490 04 Structural basis ot nephron filtration
(rats, rabbits)
•• R01HL1665805
reabsorption
ROIHL 1745804 Renal control ot sodium excretion (rats)
P50HL 1831803 0007 Pathogenesis and complications ot
hypertension Humoral factors and renal function in
experimental hypertension (rats)
P50HL 1831803 0013 Pathogenesis and complications of
hypertension Humoral factors and renal function in
human hypertension
"* ROIHL 1887503 Angiotension, prostaglandins, pressure
and the kidney (rats)
ROIHL 19057-03 Catecholamines and cyclic AMP in
cardiovascular system (rats, dogs)
** ROIHL 19366-03 Renal Starling forces in experimental
conditions (rats, rabbits)
ROIHL 1946302 Pathophysiology of acute renal failure
(rats)
ROlHL-2217201 Hypotension, renal ischemia and effect of
mannitol (dogs, rats)
ROlHL-2239001 Effect of chloride on renin (rats, dogs)
R23HL-2243801 The etiology of genetic hypertension
(rats)
ROlHL-22482-01
excretion (dogs)
•* ROlHL-2283601
(rats)
R23HL-2288201 Modulation by disease of effect of
furosemide in man
ROlHL-2360201 Physiology of renin, aldosterone and
prostaglandin (human, rats, dogs)
KIDNEY FUNCTION, SALURESIS
ROlHL-00759-29 Regulation of electrolyte and acid base
equilibrium (dogs)
ROlHL-02493-22 Kidney function in experimental heart
failure (dogs, rats)
** R01HL-03303-21 Factors regulating electrolyte excretion by
the kidney (human, dogs)
P01HL06285-18 0199 Cardiovascular-respiratory
physiology and biochemistry - Renal tubular reabsorption of
sodium chloride (hamsters, rabbits)
POlHL-06285-18 0200 Cardiovascular-respiratory
physiology and biochemistry - Medullary counter-current
system (animals)
POlHL-08682-15 0026 Regulation of the cardiovascular
system - Hypertension-High renin vs low renin (dog)
POlHL-0868215 0027 Regulation of the cardiovascular
system - Cardiac mechanoreceptors-Reflex regulation of
renal function (dogs)
R01HL10612-13 0018 Humoral factors in heart failure
and hypertension ■ The pathogenesis of experimental renal
hypertension (dogs, rabbits, rats)
R01HL10612-13 0020 Humoral factors in heart failure
and hypertension ■ The control of renin release in the dog
ROlHL-10612-13 0021 Humoral factors in heart failure
and hypertension ■ The control of aldosterone secretion
(dogs)
R01HL-10914I0 Renal sodium transport in experimental
aldosteronism (dogs)
POlHL-11678-11 0040 Cardiovascular dynamics and their
control - Control of plasma potassium concentration (dogs)
POlHL-1167811 0046 Cardiovascular dynamics and their
control ■ Regulation of aldosterone secretion and related
factors (dogs)
P01HL11678-11 0047 Cardiovascular dynamics and their
control - Unidentified pituitary factor in regulation of
aldosterone secretion (rats)
" POlHL-11678-11 0063 Cardiovascular dynamics and their
control ■ Renin-angiotensin system -Control of renal
hemodynamics, electrolyte excretion
** POlHL-11678-11 0064 Cardiovascular dynamics and their
control - Renal medulla -Control of renal hemodynamics,
electrolyte excretion (dogs)
POlHL-1 1678-11 0065 Cardiovascular dynamics and their
control - Body fluid volumes in the genesis of hypertension
(dogs)
** POIHLI 167811 0067 Cardiovascular dynamics and their
control - Angiotension II, sodium excretion and renal
hemodynamics (dogs)
P01HL1215711 0058 Functions and mechanisms of cell
membrane ion transport ■ Ionic and osmotic regulation in
toadfish~A euryhaline aglomerular teleost
POlHL-12738-10 0129 Physiologic pharmacology and its
clinical applications - Receptor specificities and
metabolism of vasopressin analogs
** ROlHL-12827-08 Regulation of sodium excretion (dogs,
rats)
ROlHL-13427-09
dogs)
R01HLI359508
Neural control of blood volume (monkeys.
Renin and vascular hyper-reactivity in
Regulation of the circulation in
Release of renal prostaglandins by
Hypertension- Genetic influence of kidney
Genesis of hypertension in renal disease
317
ROIHI 14133 08 Intrarenal regulation of sodium
leabsorption (dogs, hamsters, rats)
P50HL 14159 08 0008 Specialized center of research in
hypertension Renal function and sodium metabolism in
hypertension (rats, human, rabbits)
P50HL 14159 08 0020 Specialized center ot research in
hypertension Renin mineralocorticoid system in
hypertension (human, rat. dog)
POIHI 1438807 0157 Regulation of the circulation in
pathological states Auloregulation of renal blood flow and
distribution in sodium excretion control
POIHL 1438807 0179 Regulation of the circulation in
pathological states Cultured muscle cells and their cross
innervation in vitro (rats, sheep)
POIHL 1438807 0186 Regulation of the circulation in
pathological states Angiotension in modulation of
neurogenic vasoconstriction
POIHL 14388-07 0190 Regulation ot the circulation in
pathological states Mechanisms of the renal actions of
aldosterone (rats)
POIHL 14388 07 0191 Regulation of the circulation in
pathological states Regulation of chloride transport m
epithelial membranes (turtles)
POIHL 14388-07 0213 Regulation of the circulation in
pathological states Regulation of the heart and peripheral
circulation in heart failure
' P01HL14388-07 0222 Regulation of the circulation in
pathological states Renal perfusion pressure in
hypertension (rats)
■ POIHL 14388-07 0225
pathological states
saluretiC'diuretic agents (dogs)
ROlHL-1491306
(rats)
ROlHL-15124-05
(human, dogs)
' R01HL15839-05 Physiological role of isorenin and
kallikrein (animals)
ROlHL-16489-04 Renal prostaglandins-Synthesis and
function (human, dogs, rats)
* R01HL16658-05 Intrarenal regulation of sodium
reabsorption
* R01HL17458-04 Renal control of sodium excretion (rats)
ROlHL-17705-04 Kallikrein-kinin system in hypertension
(human, rats, dogs)
* POlHL-17871-04 0013 Kidney, sodium, cardiac output,
arterioles and hypertension - Perfusion pressure and renal
sodium excretion (rats)
* P50HL-183 1803 0007 Pathogenesis and complications of
hypertension - Humoral factors and renal function in
experimental hypertension (rats)
P50HL-183 18-03 0011 Pathogenesis and complications of
hypertension - Adrenergic function -Renin and
mineralocorticoid activity (human)
* P50HL-183 18-03 0013 Pathogenesis and complications of
hypertension ■ Humoral factors and renal function in
human hypertension
P50HL-183 18-03 0019 Pathogenesis and complications of
hypertension ■ Renin-angiotensin system in blood pressure
regulation (human, rat, dog)
P50HL18323-04 0012 SCOR hypertension center - Renin
as a risk factor (human)
P50HL- 183 23-04 0037 SCOR hypertension center ■
Adrenocortical factors in childhood hypertension
P50HL-18323-04 0044 SCOR hypertension center ■
Angiotensin blockade to identify angiotensin II factor in
hypertension (human)
R01HL18426-04 Regulation of renal hemodynamics (dogs)
'* R01HL18845-04 Regulation of renal circulation and salt
excretion (rats, dogs)
ROlHL-18875-03 Angiotension, prostaglandins, pressure
and the kidney (rats)
ROlHL-18891-02 Electrolyte intake and blood pressure in
hypertension (human)
ROlHL-19229-02 Prostaglandins and hypertension (human,
rats, dogs, rabbits)
ROlHL-19279-03 Intracellular action of aldosterone in
hypertension (human, rats)
R01HL19366-03 Renal Starling forces in experimental
conditions (rats, rabbits)
ROlHL-20768-02 Mechanisms of circulatory regulation in
heart failure (guinea pigs)
ROlHL-212 10-01 Acute renal failure following cardiac
surgery (human)
" ROlHL-21272-02 Sodium homeostasis and renal
prostaglandins (dogs)
ROlHL-21436-02
(cats)
ROlHL-22069-02
(dogs)
R23HL-22438-01
(rats)
ROlHL-22482-01
excretion (dogs)
R23HL-22728-01
ROlHL-23602-01
Autonomic control of renal function
Experimental renal arterial hypertension
The etiology of genetic hypertension
Circulatory hemodynamics and sodium
Neural control of renin secretion (dogs)
Physiology of renin, aldosterone and
hypertension (human, rats)
prostaglandin (human, rats, dogs)
KIDNEY NECROSIS
SEE KIDNEY DISORDERS, KIDNEY NECROSIS
KIDNEY PHARMACOLOGY
SEE ALSO KIDNEY DISORDERS CHEMOTHERAPY
KID
SEE ALSO KIONIY IUN(.II(JN, ANIIDIIJRI IICS
SEE ALSO KIONfY IDNCIION, UIIJRI IICS
ROIHL 00340 29 ticttrolyti! di'.lurhante in cardio renal
disease (human, dogs, rals)
" PO 1 HI 06835 I / 0061 Cardiovascular disease Studies
in renal physiology (human, rats, dogs)
ROIHL 0/835 17 fxperimenlal hypertension and renal
circulation (rats, rabbits)
POIHL 08682 15 0026 Regulation of the cardiovascular
system Hypertension High renin vs low renin (dog)
'• ROIHL 12677 10 Surgical physiologic studies of isolated
kidneys (dogs, rats)
POIHL 12738 10 0129 Physiologic pharmacology and its
clinical applications Receptor specificities and
metabolism of vasopressin analogs
'* ROIHL 1409207 Homeostatic regulation of plasma choline
(rats, dogs, chickens)
P50HL 14159 08 0008 Specialized center of research in
hypertension Renal function and sodium metabolism in
hypertension (rats, human, rabbits)
•* POIHL 14388-07 0190 Regulation of the circulation in
pathological states Mechanisms of the renal actions of
aldosterone (rats)
P01HL1438807 0225 Regulation of the circulation in
pathological states Release of renal prostaglandins by
saluretic diuretic agents (dogs)
R01HL1648904 Renal prostaglandins-Synthesis and
function (human, dogs, rats)
POlHL-17871 04 0010 Kidney, sodium, cardiac output,
arterioles and hypertension Renal prostaglandins
metabolism in hypertension (rats, dogs)
R01HL17902-04 Mammalian renal microcirculation
(hamsters)
** R01HL18097-04 Pathogenesis of acute renal failure (rats)
P50HL18318-03 0013 Pathogenesis and complications of
hypertension • Humoral factors and renal function in
human hypertension
ROlHL-18340-04 Electron microscopy of the
juxtaglomerular apparatus (rats)
** POlHL-1857503 0005 Mechanisms of vascular changes
in hypertension - Renin synthesis in normotensive and
hypertensive pigs (also rats, dogs)
ROIHL- 19428-03 Role of angiotensin sensitivity in renin
release (human)
ROlHL-20594-02 Renal enzymes that regulate blood
pressure (human, rats)
ROlHL-20861-01 Cardiorespiratoryrenal stress reactions
(dogs)
ROlHL-20895-03 0010 Cineangiographic studies of
cardiovascular system - Cortical necrosis and acute renal
failure (human, dogs, rats, rabbits)
ROlHL-21105-02 Organ specific drugs -Cardiovascular and
renal effects (dogs)
ROlHL-21210-01 Acute renal failure following cardiac
surgery (human)
ROlHL-22172-01 Hypotension, renal ischemia and effect of
mannitol (dogs, rats)
ROlHL-22306-01 Renal catecholamines- Pathophysiology
of hypertension (dogs)
R23HL-22728-01 Neural control of renin secretion (dogs)
ROlHL-22836-01 The spontaneously hypertensive kidney
(rats)
R23HL-22882-01 Modulation by disease of effect of
furosemide in man
KIDNEY PRESERVATION
** POlHL-06835-17 0061 Cardiovascular disease ■ Studies
in renal physiology (human, rats, dogs)
R01HL1267710 Surgical physiologic studies of isolated
kidneys (dogs, rats)
KIDNEY PROSTHESIS, ARTIFICIAL KIDNEY
SEE ALSO BLOOD TREATMENT, HEMODIALYSIS
SEE ALSO KIDNEY DISORDERS, RENAL FAILURE
** ROlHL-11945-10 Synthesis of artificial lung and kidney
systems (sheep, mice, swine)
ROlHL-18923-02 Steroid-induced hyperlipidemia and
hypertension (human, rats)
KIDNEY REVASCULARIZATION
SEE KIDNEY SURGERY, KIDNEY REVASCULARIZATION
KIDNEY SURGERY
SEE ALSO KIDNEY PROSTHESIS, ARTIFICIAL KIDNEY
SEE ALSO KIDNEY TRANSPLANTATION
SEE ALSO URINARY TRACT SURGERY
** P50HL-14192-08 0001 Specialized center of research in
hypertension - Surgical and medical treatment of
renovascular hypertension (human)
** P50HL-1419208 0002 Specialized center of research in
hypertension - Hypertensive patients with renal artery
stenosis
ROlHL-17364-04 'Big renin'-Biochemical and clinical
studies (human)
KIDNEY SURGERY, KIDNEY
REVASCULARIZATION
P50HL-14192-08 0002 Specialized center of research in
hypertension - Hypertensive patients with renal artery
stenosis
KIDNEY SURGERY, NEPHRECTOMY
SEE ALSO KIDNEY-CIRCULATORY DISORDERS, RENOPRIVAL
HYPERTENSION
(contd)
•Excludes routine methodology OR covers only general projects which preclude indexing
**Onented significantly to above subject.
at the specific level.
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
KID
318
LEC
Pathology of hypertensive-associated
Prorenin-Physioiogical and biocliemical
Circulatory hemodynamics and sodium
ROlHL-02334-23 Micropuncture study of kidney function
(rats, animals)
R01HL10612-13 0018 Humoral factors in heart failure
and hypertension - The pathogenesis of experimental renal
hypertension (dogs, rabbits, rats)
ROlHL-14914-06 Autoregulation of glomerular filtration
rate (rats)
R01HL19539-03
arteritis (rabbits)
** ROlHL-21274-01
analysis (human)
** ROlHL-22482-01
excretion (dogs)
R01HL-22e0301 Trace metals, vascular activity and
hypertension (rats)
ROlHL-22990-01 Angiotensin II receptors-Mechanisms of
regulation (rats)
KIDNEY TOXINS, NEPHROTOXINS
ROlHL-02334-23 Micropuncture study of kidney function
(rats, animals)
KIDNEY TRANSPLANTATION
SEE ALSO KIDNEY PRESERVATION
R01HL-04300-20 Fine structure of diseased glomeruli
(human, rats, dogs)
** P01HL06312-17 0022 Surgical cardiology • Cardiac
transplant-Experimental simultaneous heart and kidney
transplant (dogs)
P01HL-063i4-17 0061 Immunologic mechanisms in
cardiovascular disease - Role of viruses in cardiovascular
and renal disease (human, mice)
** P01HL0631417 0065 Immunologic mechanisms in
cardiovascular disease - Transplantation biology and
clinical transplantation
POlHL-06314-17 0067
cardiovascular disease
Immunologic mechanisms in
Mitogenic and antigenic activation
of lymphocyte sub-populations
M POlHL-06370-17 Cardiopulmonary and renal pathology
research center
** POlHL-06370-17 0001 Cardiopulmonary and renal
pathology research center - The humoral and cellular
mechanisms of allograft rejection (monkeys)
** POlHL-06370-17 0004 Cardiopulmonary and renal
pathology research center - Lymphocytes in graft rejection
and Immune surveillance (human)
POlHL-06835-17 0061 Cardiovascular disease - Studies
in renal physiology (human, rats, dogs)
ROlHL-07835-17 Experimental fiypertension and renal
circulation (rats, rabbits)
ROlHL-0869615 0004 Orthotopic heart transplantation -
Transplantation immunology-Avian antibody studies
(chickens, rats, rabbits)
POlHL-1 1310-12 0084 Mechanisms of cardiovascular
disease - Evaluation of cardiac function in chronic renal
failure (human)
ROlHL-13323-08 Intrarenal pressure and renal function
(human, dogs)
ROlHL-13408-05 Environmental-genetic interactions in
hypertension (rats)
R01HL13595-08 Renin and vascular hyper-reactivity in
hypertension (human, rats)
ROlHL-14913-06 Hypertension -Genetic influence of kidney
(rats)
ROlHL-15124-05
(human, dogs)
ROlHL-16219-05
uremia (human
R01HL16603-05
(animals)
ROlHL-1 7749-03 Adrenocortical factors in human
hypertension (human)
ROlHL-17902-04 Mammalian renal microcirculation
(hamsters)
ROlHL-17947-04 Experimental renal and neurogenic
hypertension (human, animals)
M POlHL-18646-03 Studies basic to heart transplantation
** POlHL-18646-03 0001 Studies basic to heart
transplantation - Individualized regulation of
immunosuppression (dogs, rats)
POlHL-18646-03 0002 Studies basic to heart
transplantation - Detection of rejection (dogs)
** POlHL-18646-03 0004 Studies basic to heart
transplantation - Presensitization-Detection, incidence and
clinical significance
** POIHL- 18646-03 0006 Studies basic to heart
transplantation ■ Reduction or elimination of existing
presensitization (human, animals)
P01HL18646-03 0009 Studies basic to heart
transplantation - Pathologic aspects of cardiac allograft
rejection (sheep, dogs)
ROlHL-18923-02 Steroid-induced hyperlipidemia and
hypertension (human, rats)
ROlHL-21274-01 Prorenin-Physioiogical and biochemical
analysis (human)
KIDNEY VISUALIZATION*
** P50HL-14192-08 0008 Specialized center of research in
hypertension - New radiographic methods-Recognition of
renovascular hypertension (human, dog)
KILLER LYMPHOCYTES
SEE BLOOD CELLS, T LYMPHOCYTES, KILLER
Genesis of hypertension in renal disease
Mechanisms of atherogenesis in chronic
rats)
Human and experimental renal diseases
KIMMELSTIEL-WILSON DISEASE
SEE CARBOHYDRATES METABOLISM DISORDERS, DIABETIC
NEPHROPATHIES
KINESTHESIS
SEE SENSORY-PERCEPTUAL PROCESSES, PROPRIOCEPTION
KINETICS (CHEMISTRY)
SEE CHEMICAL REACTIONS (DYNAMICS)
KININ, PLASMA
SEE PEPTIDES, VASOACTIVE PEPTIDES, KALLIDIN
KIN IN- ASSOCIATED HYPERTENSION
SEE CARDIOVASCULAR DISORDERS, HYPERTENSION
(SYSTEMIC), KININS-BRADYKININ-KALLIKREIN-
ASSOCIATED
KININOGENIN
SEE PEPTIDES, VASOACTIVE PEPTIDES, KALLIKREIN
KINKY HAIR SYNDROME
SEE MerABOUC DISORDERS INBORN, KINKY HAIR SYNDROME
KNEE
SEE SKELETAL SYSTEM, JOINT, KNEE
KORNBERG'S DARK REPAIR ENZYME
SEE NUCLEIC ACIDS REPAIR, DNA REPAIR (ENZYME)
KREBS CYCLE
SEE TRICARBOXYLIC ACIDS, KREBS CYCLE
KREBS-HENSELEIT CYCLE
SEE AMINO ACIDS, UREA CYCLE
KUPFFER CELLS
SEE LIVER CELLS, KUPFFER CELLS
KVEIM FACTOR
SEE NEOPUSMS RELATED INTEREST, SARCOIDOSIS. KVEIM
FACTOR
KYPHOSIS
SEE SKELETAL DISORDERS, SPINAL CURVATURES, KYPHOSIS
LABILE COMPONENT
SEE BLOOD COAGUUTION, FACTOR V
LABILE FACTOR OF QUICK
SEE BLOOD COAGULATION, FACTOR V
LABOR COMPLICATIONS
SEE PREGNANCY DISORDERS, LABOR COMPLICATIONS
LABORATORY (BIOMEDICAL) DATA COMPUTER
PROCESSING
SEE BIOMEDICAL SYSTEMS AUTOMATED, COMPUTER
PROCESSING OF LABORATORY DATA (GENERAL)
LABORATORY DIAGNOSTIC ERRORS
SEE DIAGNOSTIC QUALITY-STANDARDS
LABORATORY FACILITIES
SEE BIOMEDICAL FACILITIES
LABYRINTH
SEE EAR, UBYRINTH
LABYRINTHINE FLUIDS
SEE EAR, LABYRINTHINE FLUIDS
LACCASE
SEE OXYGENASES, MONOPHENOL MONOOXYGENASE
LACTAMS
SEE NITROARYLS, LACTAMS (GENERAL)
LACTATE DEHYDROGENASE
SEE OXIDOREDUCTASES, LACTATE DEHYDROGENASE
D-LACTATE DEHYDROGENASE
SEE OXIDOREDUCTASES, D-LACTATE DEHYDROGENASE
D-LACTATE FERRICYANIDE OXIDOREDUCTASE
SEE OXIDOREDUCTASES, D-LACTATE DEHYDROGENASE
D-LACTATE:NAD OXIDOREDUCTASE
SEE OXIDOREDUCTASES, D-LACTATE DEHYDROGENASE
LACTATES
SEE FAHY ACIDS, UCTATES
LACTATION
SEE REPRODUCTIVE SYSTEM FEMALE, MAMMARY GLANDS,
LACTATION
LACTIC DEHYDROGENASE AGENT
SEE VIRUSES, TOGAVIRUSES, RILEY VIRUS
LACTOGENIC HORMONE (PITUITARY)
SEE PITUITARY-DIENCEPHALON HORMONES, PROLACTIN
LACTONES
SEE OXOARYLS, UCTONES
LACTOPEROXIDASE
SEE PEROXIDASES, LACTOPEROXIDASE
LACTOSE INTOLERANCE
SEE METABOLIC DISORDERS INBORN, DISACCHARIDE
(OLIGOSACCHARIDE) INTOLERANCE
O-LACTOSYL CERAMIDE
SEE GLYCOSPHINGOLIPIDS, CERAMIDE DIHEXOSIDES
LACTOYL-GLUTATHIONE LYASE
SEE CARBON-SULFUR LYASES. GLYOXAUSE I
LAGOMORPHS
SEE MAMMALS, UGOMORPHS*
LAGOTHRIX
SEE MAMMALS, PRIMATES, MONKEYS AND APES
(ANTHROPOIDS, NON-HUMAN), NEW WORLD MONKEYS
(PLATYRHINES)*
LANGUAGE DEVELOPMENT
SEE INFORMATION-COMMUNICATION BEHAVIOR, UNGUAGE
DEVELOPMENT
LANGURS
SEE MAMMALS, PRIMATES, MONKEYS AND APES
(ANTHROPOIDS, NON-HUMAN), OLD WORLD MONKEYS
(CATARRHINES)*
LANOSTEROL
SEE CHOLESTANE SERIES, LANOSTEROL
LANTHANIDE SERIES
SEE METALS, RARE EARTHS
LANTHANUM
SEE METALS, RARE EARTHS, LANTHANUM
LARGE LYMPHOCYTE DEPENDENT IMMUNE
SYSTEM
SEE IMMUNITY, HUMORAL IMMUNITY
LARVA OF ANIMALS
SEE AGE (ANIMAL), IMMATURE, URVA
LARYNGEAL NERVES
SEE NERVOUS SYSTEM, CRANIAL NERVES, URYNGEAL
NERVES
LARYNGOTRACHEITIS
SEE RESPIRATORY DISORDERS, URYNGOTRACHEITIS
LARYNX
SEE RESPIRATORY SYSTEM, LARYNX
LASER MICROPROBE EMISSION SPECTROGRAPH
SEE CHEMISTRY, ANALYTICAL METHODS, SPECTROMETRY,
LASER*
LASER SPECTROMETRY
SEE CHEMISTRY, ANALYTICAL METHODS, SPECTROMETRY,
LASER*
LASERS
SEE OPTICS, LASERS*
LATENT VIRUS DISEASES
SEE VIRUS DISEASE CHARACTERISTICS. LATENT DORMANT
OR SLOW
LATERALIZATION
SEE BRAIN INTERHEMISPHERIC ACTIVITY, CEREBRAL
DOMINANCE
LATHYRISM
SEE TOXICOLOGY, PUNT POISONING, LATHYRISM
LAVAGE
SEE THERAPY, LAVAGE
LAXATIVES
SEE GASTROINTESTINAL AGENTS, LAXATIVES
LCAT DEFICIENCY
SEE METABOLIC DISORDERS INBORN, LCAT DEFICIENCY
LDL (LIPOPROTEINS)
SEE LIPOPROTEINS BLOOD, LDL
LEAD (COMPOUNDS)
SEE METALS, HEAVY METALS, LEAD
LEAD POISONING
SEE METALS POISONING, LEAD POISONING
LEARNING
SEE PSYCHOLOGY, LEARNING
LEARNING TRANSFER
SEE PSYCHOLOGY, LEARNING, TRANSFER
LECITHIN:CHOLESTEROL ACYLTRANSFERASE
DEFICIENCY FAMILIAL
SEE METABOLIC DISORDERS INBORN, LCAT DEFICIENCY
LECITHIN-CHOLESTEROL TRANSESTERASES
SEE TRANSACYLASES, LECITHIN-CHOLESTEROL
TRANSESTERASES
LECITHINASE A
SEE PHOSPHOLIPASE, LECITHINASE A
LECITHINASE C
SEE PHOSPHOLIPASE. PHOSPHATIDYLCHOLINE
CHOLINEPHOSPHOHYDROLASE
(contd)
*E>cludes routine melhodok)gy OR covers only general projects which preclude indexing at the specific level.
**Oneiited significanthf to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
EC
ECITHINASE 0
SEE PHOSPHOLIPASE. PHOSPHATIOYLCHOIINE
PHOSPHATIDOHYDROLASt
ECITHINS
SEE PHOSPHOLIPIDS. PHOSPHOGLYCtRIOES. LECITHINS
ECTINS
SEE PUNTS PROTEINS. LECTINS
fECHES
SEE HELMINTHS. ANNELIDS, LEECHES
SEE SKELETAL SYSTEM. LIMB, LEG
JGAl MEDICINE
SEE HEALTH SOCIAL CONTROL
LEGISLATION
SEE HEALTH SOCIAL CONTROL
LEISURE (ACTIVITIES)
SEE OCCUPATIONS. LEISURE
LENS
SEE EYE. LENS
LENS OPACITY
SEE EYE DISORDERS, LENS DISORDERS. CATARACT
LETHALS
SEE GENETICS. GENES, GENE EXPRESSION. LETHALS
LEUCINE
SEE AMINO ACIDS. LEUCINE
LEUKAPHERESIS
SEE BLOOD TREATMENT. LEUKAPHERESIS
LEUKEMIA
SEE NEOPLASMS OF BLOOD AND RE SYSTEM. LEUKEMIA
LEUKEMIA ACUTE
SEE NEOPLASMS OF BLOOD AND RE SYSTEM, LEUKEMIA
ACUTE
LEUKEMIA CHRONIC
SEE NEOPLASMS OF BLOOD AND RE SYSTEM, LEUKEMIA
CHRONIC
LEUKEMIA MOUSE VIRUSES
SEE VIRUSES, ONCORNA. LEUKEMIA MOUSE
LEUKEMIA MYELOID
SEE NEOPUSMS OF BLOOD AND RE SYSTEM. LEUKEMIA
MYELOID
LEUKEMIA VIRUSES (MOUSE)
SEE VIRUSES, ONCORNA. LEUKEMIA MOUSE
LEUKO-AGGLUTININS
SEE IMMUNOLOGY. ANTIBODIES, HEMAGGLUTININS, LEUKO-
AGGLUTININS
LEUKOCYTE ANTIGENS
SEE TISSUE COMPATIBILITY-TRANSPLANT. ISOALLOANTIGENS,
LEUKOCYTE
LEUKOCYTE DISORDERS
SEE BLOOD AND RE DISORDERS. LEUKOCYTE DISORDERS
LEUKOCYTE PRESERVATION
SEE BLOOD PRESERVATION. LEUKOCYTE PRESERVATION
LEUKOCYTE TRANSFER FACTOR
SEE HYPERSENSITIVITY. TRANSFER FACTOR
(HYPERSENSITIVin)
LEUKOCYTE TRANSFUSION
SEE BLOOD TRANSFUSION. LEUKOCYTE TRANSFUSION
LEUKOCYTE TYPING
SEE TISSUE COMPATIBILITY-TRANSPLANT,
HISTOCOMPATIBILITY TYPING. LEUKOCYTE TYPING
LEUKOCYTES
SEE BLOOD CELLS, LEUKOCYTES
LEUKOCYTOSIS
SEE BLOOD AND RE DISORDERS, LEUKOCYTE DISORDERS,
LEUKOCYTOSIS
LEUKOENCEPHALOPATHIES (GENERAL)
SEE NERVOUS DISORDERS. MYELINOPATHIES (GENERAL)
LEUKOPENIA
SEE BLOOD AND RE DISORDERS, LEUKOCYTE DISORDERS.
LEUKOPENIA
LEUKOPOIESIS
SEE BLOOD AND RE SYSTEM, HEMATOPOIESIS. LEUKOPOIESIS
LEUKOTAXIC FACTOR
SEE HYPERSENSITIVITY. LYMPHOKINES. LEUKOTAXIC FACTOR
LEVAMISOLE
SEE IMIDAZOLES. LEVAMISOLE
LEVARTERENOL
SEE PHENYLALKYLAMINES, CATECHOUMINES.
NOREPINEPHRINE
319
LEVULINIC ACID
SEE FATTY ACIDS, LEVULINIC ACID
LEVULOSE
SEE HEXOSES, FRUCTOSE
LH RELEASING FACTOR
SEE PITUITARY DIENCEPHALON HORMONES. LH RELEASING
FACTOR
LIBRIUM
SEE AZEPINES. DIAZEPINES, CHLOROIAZEPOXIOE
LIDOCAINE
SEE PHENYLAMIDES. LIDOCAINE
LIFE CYCLE
SEE BIOLOGY. LIFE CYCLE
LIFE EXPECTANCY
SEE AGING. LONGEVITY
UFE HISTORY
SEE BIOLOGY. LIFE CYCLE
LIFE STYLE
SEE PSYCHOLOGY. PERSONALITY. LIFE STYLE
UGANDS
SEE METAL COMPLEXES. UGANDS
UGASES
SEE ALSO CARBON-CARBON LIGASES
SEE ALSO NUCLEIC ACIDS REPAIR, DNA REPAIR (ENZYME)
ROlHL-02212 23 Coagulation of blood (human)
ROlHL-03299-21 Dietary effects on cholesterol metabolism
(rats, rabbits)
ROIHL 11822-10 Biophysical studies of macromolecular
interactions (microorganism, human)
ROlHL-18259-03 Controlled intratissue release of
prostaglandms
ROlHL-18682-03 Protein kinase and cholesterol
metabolism in aorta (rabbits)
" R01HL-2C794-02 Prostaglandin synthesis in human
platelets (also in sheep, rabbit)
ROlHL-22664-01 Regulation of myocardial cell growth
(rats, guinea pigs)
ROlHL-23945-06 Pathologic effects on cells of modified
lipoproteins (rats, human)
LIGASES, FATTY ACID SYNTHETASE COMPLEX
** ROlHL-02477-23 Biosynthesis and function of lipids
(microorganisms, rats)
ROlHL-12399-13 Specific tatty acids and cholesterol
metabolism (gerbils. rats)
ROlHL-16364-04 Regulation of lipid biosynthesis and
transport (rats, swine. Xenopus)
P60HL-17269-04 0003 National heart and blood vessel
research and demonstration center - Atherosclerosis -Fatty
acid metabolism in cardiovascular tissue (human, chicken)
R01HL-18938-03 Pulmonary fatty acid and phospholipid
metabolism (rats)
ROlHL-204 11-03 Platelet fatty acid metabolism In
diabetes (rat. rabbit, guinea pig)
LIGHT
SEE PHOTOBIOLOGY
SEE PHOTOCHEMISTRY
SEE PHOTOTHERAPY
LIGHT SCATTERING
SEE OPTICS. LIGHT SCAHERING*
LIGNOCERCIC ACID
SEE FATTY ACIDS, TETRACOSANOIC ACID
LIMBIC SYSTEM
SEE BRAIN. LIMBIC SYSTEM
LIMBS
SEE SKELETAL SYSTEM, LIMB
LIMBS MOVEMENT
SEE SKELETAL MOVEMENT, LIMBS MOVEMENT
LIMIT DEXTRINOSIS
SEE METABOLIC DISORDERS INBORN, GLYCOGENOSIS, TYPE
III
LINC COMPUTERS
SEE COMPUTER, ON-LINE COMPUTERS*
LINEAR ACCELERATORS
SEE RADIATION. PARTICLE ACCELERATORS
UNIMENTS
SEE DOSAGE FORMS
LINKAGE
SEE GENETIC MAPPING, LINKAGE
UNOLEATE:OXYGEN OXIDOREDUCTASE
SEE OXYGENASES. LIPOXYGENASE
LINOLEIC ACID
SEE FAHY ACIDS. LINOLEIC ACID
LINOLENIC ACID
SEE FAHY ACIDS, LINOLENIC ACID
UP
LIPASE
SEE UPASES. TRIACYLGIYCEROI LIPASE
LIPASES
SEE ALSO PHOSPHOIIPASE
ROIHL 06221 17 Composition and structure of plsiini
lipoproteins (human, turkeys, baboons)
POlHt 08214 15 0027 Chemical and biological properties
of lipids Biological functions diol lipids (swine, rats,
plants)
*• POIHL 08214 15 0041 Chemical and biological properties
of lipids Physico-chemical regulation of enzymes in lipid
metabolism
*• POIHL 12373 10 0006 Cardiopulmonary physiology and
pathophysiology Fatty acid metabolism Regulation,
implications (human, mammals, birds)
ROIHL 12869-09 Arterial metabolism, diabetes and
atherogenesis (rats, rabbits)
•* ROIHL 13722-08 Acid and alkaline lipases in aortas (rats,
rabbits, human)
P50HL 15062-07 0007 Study of lipoproteins, artery wall,
and atherosclerosis Physical chemistry of lipid protein
interaction (human)
ROlHL-18607-03 Metabolic and drug studies on
experimental fat embolism (mice)
** ROIHL 18723-03 Genetic heterogeneity of acid lipase-
Atherosclerosis (human)
ROlHL-19181-02 Regulation of heart cAMP-dependenI
protein kinase (rodents)
POlHL-20948-02 0002 Molecular basis of cholesterol
metabolism LDL pathway in cell lines with informative
properties other than fibroblasts
R01HL22053-02 The disordered lipid metabolism of
diabetes mellitus (chickens, mammals, human)
LIPASES, LIPOPROTEIN LIPASE
SEE ALSO LIPASES. TRIACYLGLYCEROL LIPASE
ROlHL-02942-22 Biochemistry of cardiovascular connective
tissue (human, cattle, primates)
POlHL-06285-18 0203 Cardiovascular-respiratory
physiology and biochemistry Pathways of lipid transport
in the blood (animals)
POlHL-06285-18 0204 Cardiovascular-respiratory
physiology and biochemistry - Lipoprotein lipase and
triglyceride transport in chylomicrons (guinea pig. rat)
** POlHL-06285-18 0205 Cardiovascular-respiratory
physiology and biochemistry - Assimilation of cholesterol in
chylomicrons and VLDL (rabbits)
ROlHL-10933-13 Fat metabolism and atherosclerosis
(rabbits, cattle, human, rats)
POlHL-11310-12 0103 Mechanisms of cardiovascular
disease - Heparin -Metabolism and function
ROlHL-12085-10 Lipoprotein-carbohydrate metabolism
(human, rats)
POlHL-12373-10 0006 Cardiopulmonary physiology and
pathophysiology - Fatty acid metabolism-Regulation,
implications (human, mammals, birds)
ROlHL-12740-10 Hypocholesterolemic agents-
Stereochemistry (rats)
** R01HL-13626-06 Upoprotein lipase and lipoprotein
removal (human, rats, bacteria)
P50HL-14230-07 0092 A/S SCOR-Lipids. atherosclerosis
and thrombosis - Tissue lipids-Cell culture studies
(human)
P50HL-14230-07 0096 A/S SCOR-Lipids. atherosclerosis
and thrombosis - Ultrastructural studies of endothelial cells
(human)
P50HL-14237-07 0001 Support for arteriosclerosis center
- Role of apolipoproteins in lipoprotein catabolism (human,
rats)
** P50HL-14237-07 0002 Support for arteriosclerosis center
- Interactions of lipoprotein particles with vascular surface
(human, rat)
ROlHL-14456-07 Lung metabolism-Enzymes in the
pulmonary circulation (human, animals)
** ROlHL-14990-07 Lipid transport in avian species
(chickens)
P50HL-15062-07 0001 Study of lipoproteins, artery wall,
and atherosclerosis - Structure and molecular interactions
of serum lipoproteins (human, monkey)
P50HL-15062-07 0008 Study of lipoproteins, artery wall.
and atherosclerosis - Lipid modifying enzymes (human.
monkey)
P50HL-15062-07 0013 Study of lipoproteins, artery wall.
and atherosclerosis - Radioimmunoassay of apolipoproteins
(human, monkeys)
P50HL-15062-07 0018 Study of lipoproteins, artery wall,
and atherosclerosis Reversal of atherosclerosis in
monkeys
ROlHL-15648-06 Lipid metabolism-Transport by lateral
diffusion (human, rabbit, cattle)
ROlHL-15930-06 Hormonal control of lipid and lipoprotein
synthesis (rats)
ROlHL-162 19-05 Mechanisms of atherogenesis in chronic
uremia (human, rats)
** R01HL-16577-04 Lipoprotein lipase chemistry and function
(rats, cattle, human)
P60HL- 17269-04 0011 National heart and blood vessel
research and demonstration center - Upoprotein structure
laboratory (human)
P50HL-18318-03 0015 Pathogenesis and complications of
hypertension - Cultured smooth muscle cells and
microvessel metabolism (mammals)
(cortd)
•Excludes routine methodology OR covers only general projects which preclude ii
"Ofiented significantly to above subject.
ndexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
LIP
320
UP
" POlHL-18574-03 0006 Lipoprotein methodology and
biomedical applications - Lipoprotein transformation,
lipolytic enzymes, diet and lipid lowering agents
ROlHL-18687-03 Pathophysiology of genetic
hypertriglycerinemias (human)
** ROlHL-18705-03 Regulation of plasma triglyceride
metabolism (rats)
ROlHL-18712-03 Iron deficiencyhyperlipidemia in
development (rats)
P50HL18828-03 0008 Specialized center of research in
thrombosis - Biochemistry, physiology -Platelets and
subcellular platelet particles (human)
** ROlHL-19056-03 Blood triglycerides and lipoprotein lipase
in the lung (rats)
ROlHL-20397-03 VLDL-TG metabolism in diabetes mellitis
(human, rat)
ROlHL'20408-03 Hyperlipidemia in diabetics during
muscular training (human)
ROlHL-22618-01 Role of apolipoproteins in
hypertriglyceridemia (human)
** POlHL-22619-01 0011 Cellular mechanisms of heart
failure - Reaction of lipoproteins and apolipoproteins with
lipoprotein lipase (cattle)
POlHL-22619-01 0012 Cellular mechanisms of heart
failure - Apolipoproteins in hypertriglyceridemia (human)
** ROlHL-22967-01 Structure and function of heparin
releasable lipases (swine, human)
ROlHL-23142-01 Mechanisms of membrane injury in
myocardial ischemia (dog)
NOlHV-12159-09 Lipid research clinic
LIPASES, TRIACYLGLYCEROL LIPASE
SEE ALSO LIPASES, LIPOPROTEIN LIPASE
ROlHL-14397-07 Hypertension-Angiotensin and
prostaglandin pharmacology (animals)
ROlHL-21513-02 Metabolism of trans fatty acids (human,
rats, swine)
** ROlHL-2296701 Structure and function of heparin
releasable lipases (swine, human)
LIPEMIA
SEE LIPIDS BLOOD, HYPERCHOLESTEREMIA
SEE LIPIDS BLOOD, HYPERLIPEMIA
SEE LIPOPROTEINS BLOOD, HYPERLIPOPROTEINEMIA
LIPEMIA CLEARING FACTOR
SEE LIPASES, LIPOPROTEIN LIPASE
LIPID BILAYER MEMBRANE
SEE BIOLOGICAL TRANSPORT, MEMBRANE MODELS
LIPID BIOSYNTHESIS
SEE LIPIDS METABOLISM, LIPOGENESIS
LIPID HAPTENS (CARDIOLIPIN)
SEE PHOSPHOLIPIDS, PHOSPHOGLYCERIDES, CARDIOLIPINS
LIPID METABOLISM
SEE LIPIDS METABOLISM
LIPID MOBILIZING FACTORS
SEE ALSO LIPASES
SEE ALSO LIPOTROPIC FACTORS
P50HL-14197-07 0006 Support for center of research on
arteriosclerosis - Diets and drugs affecting lipid
metabolism (human)
ROlHL-14713-06 Hypothermia and the heart (bats, guinea
pigs)
ROlHL-17332-04 Use of the gut for therapy of coronary
artery disease (mammals)
LIPID MOBILIZING FACTORS PITUITARY
SEE ALSO PITUITARY-DIENCEPHALON HORMONES, ACTH
SEE ALSO PITUITARY-DIENCEPHALON HORMONES,
SOMATOTROPIN
SEE ALSO PITUITARY-DIENCEPHALON HORMONES,
THYROTROPIN
SEE ALSO PITUITARY-DIENCEPHALON HORMONES,
VASOPRESSIN
** ROlHL-221 15-02 Lipid-mobilization and diabetic
atherosclerosis (human)
LIPID PEROXIDES
SEE LIPIDS, OXIDIZED LIPIDS, LIPID PEROXIDES
LIPID PIGMENTS
SEE LIPOFUSCIN-CEROID
LIPID SOLUBILITY
SEE PHYSICAL PROPERTIES, SOLUBILITY, LIPID
LIPIDOSIS (NEUTRAL), INBORN ERRORS
SEE METABOLIC DISORDERS INBORN, LIPID (NEUTRAL)
STORAGE
UPIDS
SEE ALSO CONNECTIVE TISSUE, ADIPOSE
SEE ALSO ENDOCRINOLOGY, HORMONES, STEROID
HORMONES
SEE ALSO FATTY ACIDS
SEE ALSO GLYCOLIPIDS
SEE ALSO GLYCOSPHINGOLIPIDS
SEE ALSO LIPASES
SEE ALSO LIPIDS BLOOD
SEE ALSO LIPOFUSCIN-CEROID
SEE ALSO LIPOIDAL DISORDERS
SEE ALSO LIPOPROTEINS
SEE ALSO NUTRITION, DIETARY CONSTITUENTS, DIETARY
LIPIDS
SEE ALSO PHOSPHOLIPIDS
SEE ALSO POLYSACCHARIDES, LIPOPOLYSACCHARIDES
SEE ALSO PROTEOLIPIDS
SEE ALSO SLOW REACTING SUBSTANCES
SEE ALSO STEROIDS
SEE ALSO STEROLS
SEE ALSO TRIOSE ALCOHOLS. GLYCERIN
R01HL-05949-18 Biochemistry of muscle contraction (rats,
rabbits)
POlHL-082 14-15 0006 Chemical and biological properties
of lipids - Analysis and properties of lipids
POlHL-082 14-15 0010 Chemical and biological properties
of lipids - Infrared spectroscopy of lipids
POlHL-082 14-15 0040 Chemical and biological properties
of lipids - Nuclear magnetic resonance studies of lipids
POlHL-082 14-15 0047 Chemical and biological properties
of lipids - High resolution liquid chromatography for the
analysis of biological substances
ROlHL-13256-08 Amino acid transport by red cell
membranes (pigeons)
ROlHL-14825-05 External isotope assay of atherosclerosis
(rats, rabbits)
ROlHL-16029-05 Bio-organic chemistry of ozone, nitrogen
dioxide and tobacco smoke
R01HL-16101-05 Protein-lipid interaction (bacteria,
models)
POlHL-16137-05 0001 Alveolar biology - Chemical
characterization of surfactant system-Lipid and lipid
protein fractions
POlHL-164 11-04 0004 Blood systems in coagulation and
vessel disease - Platelets reactions in vascular injury
(human, animals)
P60HL-17269-04 0009 National heart and blood vessel
research and demonstration center - Physical methods
laboratory (high density lipoproteins)
P60HL-172e9-04 0013 National heart and blood vessel
research and demonstration center - Peptide synthesis
laboratory (human)
P60HL-1 7269-04 0014 National heart and blood vessel
research and demonstration center - Physio-chemical nature
of lipid deposits in arterial wall (human)
POlHL-18208-04 0007 Center for the study of blood cell
rheology - RBC membrane protein (human)
ROlHL-18551-03 Spectrin, actin, lipid and red cell
membrane structure
ROlHL-18607-03 Metabolic and drug studies on
experimental fat embolism (mice)
ROlHL-18623-12 Physical chemistry of biologically active
lipids (bacteria, plant, cattle, human)
R01HL-19011-03 Smooth muscle cell membrane
glycoprotein biosynthesis (cattle)
ROlHL-19252-02 Vascular connective tissue-Role in
atherosclerosis (rabbits)
R01HL-19287-03 The antihypertensive function of the
renal medulla (human, rats, rabbits)
ROlHL-19381-03 Pathogenesis of viral induced
atherosclerosis (human, chicken)
R23HL-19605-01 Lipid requirement of the lung mono-
oxygenase system (rabbits)
ROlHL-19639-02 Permeability transients of carriers,
channels and heart
ROlHL-19806-03 Chemotactic control of airway phagocytes
(human, rabbits)
ROlHL-20063-03 Pathogenesis of pulmonary mycoplasma
infections (guinea pigs, mice)
ROlHL-20859-02 Beta adrenergic catecholamine receptor
ROlHL-21239-02 Isolation and mechanism of action of
thromboxane A2 (human, rabbits)
ROlHL-21404-01 Raman spectroscopy of erythrocyte and
model membranes (human)
ROlHL-22432-01 Molecular studies of human erythrocyte
membranes
POlHL-22602-01 0004 Pathophysiology of the
endothelium - Endothelium, platelets smooth muscle and
atherosclerosis (rabbits)
POlHL-226 19-01 0001 Cellular mechanisms of heart
failure - Cell membrane isolation and reconstitution (dogs,
lambs)
P01HL-22633-01 0004 Cellular and molecular biology of
lipoprotein metabolism - Lipid-lipid and lipid-protein
interactions in serum lipoproteins (human, rats)
ROlHL-23003-01
esters
ROlHL-23013-01
(chick embryo)
ROlHL-23183-01 Voltage dependent conductance in
membranes
NOlHR-52957-02
(human, swine)
NOlHV-22917-11
NOlHV-22932-09
Bulk-surface distribution of cholesteryl
Smooth muscle development in vitro
Composition of respiratory mucus
Lipid research clinic (human)
Establishment of a lipid research clinic
POlHL-06285-18 0205 Cardiovascular-respiratory
physiology and biochemistiy - Assimilation of cholesterol In
chylomicrons and VLDL (rabbits)
POlHL-06285-18 0207 Cardiovascular-respiratory
physiology and biochemistry - Feedback control of
cholesterol synthesis in non-hepatic tissues (animals)
ROlHL-10642-18 Plasma cholesterol metabolism (human,
macaca)
ROlHL-10933-13 Fat metabolism and atherosclerosis
(rabbits, cattle, human, rats)
P50HL-14164-07 0033 A/S SCOR-Comparative and
experimental atherosclerosis - Comparative studies of
lipoprotein distribution and metabolism (monkeys)
P50HL-14164-07 0037 A/S SCOR-Comparative and
experimental atherosclerosis - Genetic control of plasma
cholesterol-Interaction of dietary fatty acid (monkey)
P50HL-14197-07 0007 Support for center of research on
arteriosclerosis - Metabolic defects in familial
hyperlipoproteinemias (human)
P50HL-14237-07 0001 Support for arteriosclerosis center
- Role of apolipoproteins in lipoprotein catabolism (human,
rats)
P50HL-14237-07 0002 Support for arteriosclerosis center
- Interactions of lipoprotein particles with vascular surface
(human, rat)
ROlHL-14313-07 Apoproteins of triglyceride rich
lipoproteins (human, squirrel monkeys, rats)
ROIHL- 15648-06 Lipid metabolism -Transport by lateral
diffusion (human, rabbit, cattle)
POlHL-18574-03 0004 Lipoprotein methodology and
biomedical applications - Fine structure and metabolism of
lipoproteins-EM studies (guinea pigs)
POlHL-18574-03 0006 Lipoprotein methodology and
biomedical applications - Lipoprotein transformation.
lipolytic enzymes, diet and lipid lowering agents
ROlHL-19056-03 Blood triglycerides and lipoprotein lipase
in the lung (rats)
ROlHL-22123-02 The role of the red cell in diabetic
atherosclerosis (human)
Cellular and molecular biology of
Sterol metabolism in tissue
POlHL-22633-01 0002
lipoprotein metabolism
culture cells
LIPIDS, CHYLOMICRONS
POlHL-06285-18 0203 Cardiovascular-respiratory
physiology and biochemistry - Pathways of lipid transport
in the blood (animals)
** POlHL-06285-18 0204 Cardiovascular-respiratory
physiology and biochemistry - Lipoprotein lipase and
triglyceride transport in chylomicrons (guinea pig, rat)
LIPIDS, FATS
POlHL-06285-18 0204 Cardiovascular-respiratory
physiology and biochemistiy - Lipoprotein lipase and
triglyceride transport in chylomicrons (guinea pig, rat)
P01HL-08214-I5 0047 Chemical and biological properties
of lipids - High resolution liquid chromatography for the
analysis of biological substances
POlHL-12373-10 0006 Cardiopulmonary physiology and
pathophysiology - Fatty acid metabolism-Regulation,
implications (human, mammals, birds)
ROlHL-12740-10 Hypocholesterolemic agents-
Stereochemistry (rats)
P50HL-14141-05 0008 SCOR for atherosclerosis In
childhood - Core laboratory
P50HL-1 5103-07 0013 A/S SCOR-Early natural history of
arteriosclerosis - Experimental models of atherosclerosis
(monkeys)
POlHL-15596-05 0018 Coagulation, fibrinolysis,
hemostasis and hepatitis - Increased plasma lipids on
blood coagulation and thrombosis (human, animals)
R01HL-16219-05 Mechanisms of atherogenesis in chronic
uremia (human, rats)
ROlHL-17332-04 Use of the gut for therapy of coronary
artery disease (mammals)
ROlHL-18607-03 Metabolic and drug studies on
experimental fat embolism (mice)
ROlHL-20397-03 VLDL-TG metabolism In diabetes mellitis
(human, rat)
LIPIDS, FATS, SATURATED FATS
SEE ALSO FATTY ACIDS, SATURATED FATTY ACIDS
POlHL-08974-14 0024 Natural and experimental
atherosclerosis - Atherosclerosis, sterol and lipoprotein
metabolism in nonhuman primates
ROlHL-12399-13 Specific fatty acids and cholesterol
metabolism (gerbils, rats)
R01HL-14781-08 Lipid deposition in mammalian cells
(mice)
ROlHL-19223-03 Control of cholesterogenesis in leukocytes
and liver (rats, human)
P50HL-19362-02 0001 A/S SCOR-Atherosclerosis in
nonhuman primates - Effects of infant nutrition on
atherosclerosis (baboons)
LIPIDS, FATS, UNSATURATED FATS
SEE ALSO FATTY ACIDS. UNSATURATED FATTY ACIDS
P50HL-14197-07 0006 Support for center of research on
arteriosclerosis - Diets and drugs affecting lipid
metabolism (human)
ROlHL-14781-08 Lipid deposition in mammalian cells
(mice)
ROlHL-14990-07 Lipid transport in avian species
(chickens)
P50HL-19362-02 0001 A/S SCOR-Atherosclerosis in
nonhuman primates - Effects of infant nutrition on
atherosclerosis (baboons)
POlHL-20993-02 0004 Population dynamics of arterial
cells in atherogenesis - Modifications of cholesterol balance
related to arterial cell divisions (swine)
(contd)
^Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
••Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
* R01HL231S9'01 Regulation ol lipogenesis by
polyunsaluiated lats (cats, chicks)
IPIDS, GLYCERIDES
SEE ALSO LIPIDS. fATS
SEE ALSO PHOSPHOIIPIDS. PHOSPHOGLYCERIOES
P01HL08214 lb 0041 Chemical and biological properties
at lipids Physico^hemical regulation ol enzymes in lipid
metabolism
ROIHL 20189 01 Etiects of renin on atherogenesis
(rabbits)
JPIDS, GLYCERIDES, DIGLYCERIDES
ROIHL 21628 02 Biosynthesis ol lung surfactant lipid
(rabbit)
JPIDS, GlYCERIOES, TRIGLYCERIDES
R01HL03299-21 Dietary eftects on cholesterol metabolism
(rats, rabbits)
P01HL0630818 0040 Mechanisms and therapy ot
circulatory disease Metabolism and tatty acid utilijation-
Heart electrical stability (rats, dogs)
POIHL 06835 17 0064 Cardiovascular disease ■ Studies
in atherosclerosis (human, animals)
ROlHL-08506 15 Lipemia-carbohydrate and glyceride
metabolism (human, rats)
P01HL0897414 0024 Natural and experimental
atherosclerosis Atherosclerosis, sterol and lipoprotein
metabolism in nonhuman primates
R01HL0948913 Myocardial lipid metabolism and
regulation (rats)
P50HL 1416407 0030 A/S SCOR-Comparative and
experimental atherosclerosis ■ Morphology, angiochemistry-
Diet induced lesions in African green monkey
P50HL1416407 0034 A/S SCOR-Comparative and
experimental atherosclerosis Core lipid analytic laboratory
P50HL-1416407 0041 AyS SCOR-Comparative and
experimental atherosclerosis ■ Nonhuman primate pediatric
atherosclerosis risk factor
P50HL14197-07 0005 Support for center of research on
arteriosclerosis - Lipoprotein biosynthesis and degradation
in vivo and in vitro (human, animal)
P50HL-14197-07 0006 Support for center of research on
arteriosclerosis ■ Diets and drugs affecting lipid
metabolism (human)
P50HL1419707 0007 Support for center of research on
arteriosclerosis - Metabolic defects in familial
hyperlipoproteinemias (human)
P50HL14230-07 0088 A/S SCOR-Lipids, atherosclerosis
and thrombosis ■ Coronary risk factors in school children-
The Muscatine study
P50HL1423007 0092 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Tissue lipids-Cell culture studies
(human)
P50HL14230-07 0094 A/S SCOR-Lipids. atherosclerosis
and thrombosis - Studies of atherosclerosis and regression
(monkeys)
P50HL14230-07 9001 A/S SCOR-Lipids, atherosclerosis
and thrombosis ■ Core lipid laboratory
P50HL-14236-05 0006 Prevention of premature
arteriosclerosis - Carbohydrate metabolism and
hypertriglyceridemia (human)
P50HL-14237-07 0001 Support for arteriosclerosis center
• Role ot apolipoproteins in lipoprotein catabolism (human,
rats)
P50HL-14237-07 0002 Support for arteriosclerosis center
■ Interactions of lipoprotein particles v«ith vascular surface
(human, rat)
P50HL14237-07 0003 Support for arteriosclerosis center
- Structure of lipoproteins and apolipoproteins (human,
rabbits)
P50HL14237-07 0005 Support for arteriosclerosis center
- Genetic determinants of apolipoprotein variability in
lipoproteins (human)
P50HL14237-07 0007 Support for arteriosclerosis center
Core laboratories
ROlHL-14990-07 Lipid transport in avian species
(chickens)
P01HL15265-05 0003 Program on surgical control of the
hyperlipidemias - Central lipid laboratory
ROlHL-1530807 Assays tor peptides of lipoproteins
(human)
R01HL15797-05 Lipid metabolism and atherosclerosis in
primates (monkeys, human, squirrels)
ROlHL-16059-06 Structure and function of serum
lipoproteins (cattle, human)
ROlHL-16587-04 Cholesterol binding saponins and
atherosclerosis (monkeys)
R01HL-16807-02 Lipid structure of normal and
hyperlipoproteins (human)
R01HL17516-04 Role ot androgen as a risk factor in
atherogenesis (human, animals)
RDlHL-17721-04 Effect of sex hormones on vascular
connective tissue (rats)
** R01HL1868703 Pathophysiology of genetic
hypertriglycerinemias (human)
** ROlHL-18705-03 Regulation of plasma triglyceride
metabolism (rats)
ROlHL-1872303 Genetic heterogeneity ot acid lipase-
Atherosclerosis (human)
POlHL-1882702 0001 Platelet vessel wall interactions in
thrombogenesis - Role of endothelial cells in the production
ot thrombi (human, cattle)
;)7 1
■* ROIHL 1905603 Blood triglycerides and lipoprotein lipil*
in the lung (rats)
ROIHI 1910903 Regression ol chronic atherosclerosis
(rabbits)
P50HL 21006 02 0002 Specialized center ol research in
arteriosclerosis Turnover and metabolism ol cholesterol in
man
R23HL 21251 01 Metabolism of neutral lipids in the
pulmonary alveolus (rabbits)
** ROIHL 21764 01 Ultramicioanalysis ot prostaglandins and
related compounds (rats)
R23HL 21842 01 Control ot sugar entry in normal and
diabetic heart (rats)
ROIHL 22121 02 Dyslipoproteinemia in diabetes and
vascular disease (human)
•* R01HL2261801 Role of apolipoproteins in
hypertriglyceridemia (human)
POIHL 22619-01 0011 Cellular mechanisms of heart
failure Reaction of lipoproteins and apolipoproteins with
lipoprotein lipase (cattle)
** POlHL-22619 01 0012 Cellular mechanisms of heart
failure Apolipoproteins in hypertriglyceridemia (human)
** ROIHL 22748 01 Effect ot bile sequestration on VLDL
metabolism (human)
ROlHL-2284701 Test lor adherence to diets rich in
linoleic acid
ROIHL 22967-01 Structure and lunction ol heparin
releasable lipases (swine, human)
ROlHL-2300301 Bulk-surface distribution ot cholesteryl
esters
ROlHL-231 59-01 Regulation ot lipogenesis by
polyunsaturated fats (rats, chicks)
ROlHL-236 18-01 Substrate metabolism in isolated
myocytes in shock (dogs, rats, guinea pigs)
LIPIDS, GLYCERYL ETHERS
SEE ALSO PHOSPHOLIPIDS, PHOSPHOGLYCERIOES,
PLASMALOGENS
R01HL09489-13 Myocardial lipid metabolism and
regulation (rats)
LIPIDS, OILS, CROTON OIL
POlHL-03 174-23 0011 Mechanisms ot acute vascular
reaction to injury - Mutagen metabolism by artery wall in
etiology ot atherosclerosis (human, animals)
** P01HL15596-05 0012 Coagulation, fibrinolysis,
hemostasis and hepatitis - Platelet lunction-Phorbol ester
and zymosan-induccd release activity
LIPIDS, OILS, VEGETABLE OILS
P01HL06835-17 0014 Cardiovascular disease - Dietary
induction ol severe atherosclerosis and its prevention
(dogs)
POlHL-06835-17 0016 Cardiovascular disease - Metabolic
interactions to polyunsaturated fatty acids in atherogenic
diet (dogs)
LIPIDS, OXIDIZED LIPIDS, LIPID PEROXIDES
** ROlHL-1816304 Red cell membrane eftects due to
oxidizing agents
ROlHL-19633-02 Pathogenesis and pharmacology of lung
fibrosis (rats, rabbits)
LIPIDS, WAXES
POlHL-082 14-15 0048 Chemical and biological properties
of lipids - Lipids in microorganisms and plants
LIPIDS BIOSYNTHESIS
SEE LIPIDS METABOLISM, LIPOGENESIS
LIPIDS BLOOD
SEE ALSO LIPIDS, CHYLOMICRONS
SEE ALSO LIPOPROTEINS BLOOD
ROlHL-03299-21 Dietary effects on cholesterol metabolism
(rats, rabbits)
POlHL-06835-17 0014 Cardiovascular disease - Dietary
induction of severe atherosclerosis and its prevention
(dogs)
POlHL-06835-17 0015 Cardiovascular disease - Plasma
cholesterol esterification in canine atherosclerosis
PClHL-06835-17 0016 Cardiovascular disease - Metabolic
interactions to polyunsaturated fatty acids in atherogenic
diet (dogs)
** POlHL-06835-17 0017 Cardiovascular disease - Studies
on obese hypertensive rats
POlHL-06835-17 0018 Cardiovascular disease - Fatty
acid concentration (rats)
POlHL-0683517 0021 Cardiovascular disease - Animal
study in atherosclerosis (dog, guinea pig)
POlHL-06835-17 0022 Cardiovascular disease - Arterial
lipogenesis from glucose in the rat
** POlHL-06835-17 0026 Cardiovascular disease •
Lipoproteins (human, guinea pig)
POlHL-06835-17 0064 Cardiovascular disease ■ Studies
in atherosclerosis (human, animals)
ROlHL-06924-16 Humoral and metabolic aspects of
cardiac function (mammals, non-human, human)
ROlHL-08888-12 Cooperative study of drugs and coronary
heart disease (men)
** POlHL-08974-14 9001 Natural and experimental
atherosclerosis - Core -Lipid chemistry laboratory
ROlHL-10445-09 Cooperative study of drugs and coronary
heart disease (men)
M
LIP
ROIHI 113/2 08 Coopecalivt Jtudy ol druji and coronary
heart disease (men)
ROIHI 11901 12 0012 Fltects ol metabolic turgery on
the hyperlipidemias Ileal bypass Animal atheroscleroju
implications (pigeons, dogs, rabbits)
ROIHL 11901 1? 0015 Ellecis ol metabolic surgery on
the hyperlipidemias Portacaval shunt lor cholesterol
reduction (dogs, rabbits)
ROIHL 129/4 10 Tracer kinetics. Hows and masses in
body organs (human, dogs)
P50HL 14138 05 0008 Center tor research on
atherosclerosis Core lipid laboratory (human)
P50HL 14141 05 SCOR lor atherosclerosis in childhood
P50HL 14141 05 0001 SCOR lor atherosclerosis in
childhood Clinical implications (inlants and children)
P50HL-14141 05 0002 SCOR lor atherosclerosis in
childhood Intrauterine environment ol proband group
(human)
P50HL 14141 05 0007 SCOR tor atherosclerosis in
childhood Relation ol lipid valves to sexual maturation at
puberty (human)
P50HL 14141-05 0008 SCOR lor atherosclerosis in
childhood Core laboratory
P50HL 14164 07 A/S SCOR-Comparative and experimental
atherosclerosis
P50HL 14164 07 0029 A/S SCOR-Comparative and
experimental atherosclerosis - Development ol pigeon
substrains
P50HL- 14 164-07 0030 A/S SCOR-Comparative and
experimental atherosclerosis Morphology, angiochemistry
Diet induced lesions in Atrican green monkey
P50HL-14164-07 0032 A/S SCOR-Comparative and
experimental atherosclerosis Plasma cholesterol, lesion
regression and vascular lunction (Rhesus monkey)
■ P50HL-14164-07 0034 A/S SCOR-Comparative and
experimental atherosclerosis Core lipid analytic laboratory
P50HL-14164-07 0037 A/S SCOR-Comparative and
experimental atherosclerosis - Genetic control ol plasma
cholesterol-Interaction of dietary fatty acid (monkey)
P50HL-141b4-07 0038 A/S SCOR-Comparative and
experimental atherosclerosis - Peripheral vascular studies-
Cholesterol, lesion regression, vascular lunction
P50HL-14164-07 0041 A/S SCOR-Comparative and
experimental atherosclerosis - Nonhuman primate pediatric
atherosclerosis risk lactor
P50HL-14214-07 0031 Newborn lung center for hyaline
membrane disease - Essential fatty acid deficiency and
HMD (human)
P50HL-14230-07 A/S SCOR-Lipids, atherosclerosis and
thrombosis
P50HL-1423007 0092 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Tissue lipids-Cell culture studies
(human)
P50HL 1423007 0093 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Clinical studies involving cellular lipid
content (human)
P50HL-14230-07 0094 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Studies of atherosclerosis and regression
(monkeys)
P50HL-14230-07 9001 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Core lipid laboratory
P50HL-14236-05 0005 Prevention of premature
arteriosclerosis ■ Genetically hyperlipidemic and
hypolipidemic rats
P50HL-14236-05 0012 Prevention of premature
arteriosclerosis - Automated lipid analysis
P50HL-14237-07 0005 Support for arteriosclerosis center
■ Genetic determinants of apolipoprotein variability in
lipoproteins (human)
Support tor arteriosclerosis center
P50HL-14237-07 0007
- Core laboratories
P50HL-15062-07 0018
and atherosclerosis
monkeys
P50HL-15062-07 0021
and atherosclerosis
P50HL-1 5103-07 0001
Study of lipoproteins, artery wall.
Reversal ot atherosclerosis in
Study of lipoproteins, artery wall.
Core laboratories
A/S SCOR-Early natural history of
arteriosclerosis - Clinical research-Bogalusa heart study
(children)
ROIHL-15174-06 CV disease epidemiology-Second
generation studies (human)
POlHL-15265-05 0003 Program on surgical control ot the
hyperlipidemias - Central lipid laboratory
POlHL-15265-05 0013 Program on surgical control of the
hyperiipidemias - Clinical center - Minnesota
ROlHL-15528-05 Renin kinetics in hypertensive and
uremic plasma (human, dogs)
POlHL-15596-05 0001 Coagulation, fibrinolysis,
hemostasis and hepatitis - Defibrination (human)
POlHL-15596-05 0018 Coagulation, fibrinolysis,
hemostasis and hepatitis - Increased plasma lipids on
blood coagulation and thrombosis (human, animals)
ROlHL-15797-05 Lipid metabolism and atherosclerosis in
primates (monkeys, human, squirrels)
ROlHL-15930-06
synthesis (rats)
ROlHL-16774-04
Hormonal control of lipid and lipoprotein
Genetic epidemiology of hyperlipemia
(Honolulu)
ROlHL-16952-05 Cardiovascular pathology (rats, rabbits)
P60HL-17269-04 0043 National heart and blood vessel
research and demonstration center - Dietary modification-
Effect on cardiovascular risk parameters (human)
(contd)
•Excludes routine methodology OR covers only general projects which preclude
'•Oriented significantly to above subject.
indexing at the specific level.
M Grant has subprojects describing specific research aspects
See Appendix for investigator's name and grant number.
UP
ROlHL-17564-03 Unsaturated fats-Mode of
hypocholesterolemic action (minlpig)
P50HL-17e67-04 0001 Study of ischemic heart disease -
Natural history of ischemic heart disease (human)
ROIHL- 1823 5-03 Cardiovascular fitness and other risk
factors (human)
P50HL-18318-03 0003 Pathogenesis and complications of
hypertension - Core biochemical laboratory
ROlHL-18705-03 Regulation of plasma triglyceride
metabolism (rats)
ROlHL-18923-02 Steroid-induced hyperlipldemia and
hypertension (human, rats)
R01HL19083-02 Rapid specific micro measurement of
blood cholesterol
R01HL19109-03 Regression of chronic atherosclerosis
(rabbits)
P50HL-19362-02 0001 A/S SCOR-Atherosclerosis in
nonhuman primates - Effects of infant nutrition on
atherosclerosis (baboons)
P50HL-19362-02 0003 A/S SCOR-Atherosclerosis in
nonhuman primates - Heritability of characters related to
atherosclerosis (baboons)
P50HL-19382-02 0004 A/S SCOR-Atherosclerosis in
nonhuman primates - Selective breeding for characters
related to atherosclerosis (baboons)
P50HL-19362-02 0006 A/S SCOR-Atherosclerosis in
nonhuman primates - Effects of cigarette smoking on
atherosclerosis (baboon)
P50HL-19362-02 0013 A/S SCOR-Atherosclerosis in
nonhuman primates - Core laboratory-Lipid biochemistry
(baboons)
ROlHL-20124-02 Coronary risk factors (human)
ROlHL-20189-01 Effects of renin on atherogenesis
(rabbits)
ROlHL-20408-03 Hyperlipldemia in diabetics during
muscular training (human)
ROlHL-20411-03 Platelet fatty acid metabolism in
diabetes (rat, rabbit, guinea pig)
ROlHL-20428-03 The juvenile diabetic heart (human)
ROlHL-20508-03 Diabetes, hyperglycemia and
cardiovascular disease (human)
ROlHL-20522-03 Peripheral arterial disease in the diabetic
(human)
R01HL-205G4-02 Pathogenesis of peripheral arterial
disease (rats, rabbits)
P50HL-21006-02 Specialized center of research in
arteriosclerosis
P50HL-21006-02 0001 Specialized center of research In
arteriosclerosis - Clinic and core program
ROlHL-22847-01 Test for adherence to diets rich in
linoleic acid
ROlHL-23981-01
NOlHV-1215714
NOlHV-22915-11
NOlHV-22916-16
N01HV-42933-09
disease (human)
Acute alveolar injury (dogs)
Lipid research clinic (human)
Establishment of lipid research clinic
Establishment of a lipid research clinic
Multiple risk factors in coronary heart
LIPIDS BLOOD, HYPERCHOLESTEREMIA
SEE ALSO LIPOPROTEINS BLOOD, HYPERLIPOPROTEINEMIA
SEE ALSO METABOLIC DISORDERS INBORN,
HYPERLIPOPROTEINEMIAS FAMILIAL, TYPE II
SEE ALSO METABOLIC DISORDERS INBORN,
HYPERLIPOPROTEINEMIAS FAMILIAL, TYPE III
SEE ALSO METABOLIC DISORDERS INBORN, LCAT DEFICIENCY
** ROlHL-01803-23 0010 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Atherosclerosis Induction-Graft rejection
and hypercholesterolemia (rabbits)
ROlHL-01803-23 0014 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Regenerated endothelium on lipid
accumulation in arterial wall (rabbit)
ROIHL 02965-22 Metabolism uf plasma lipoproteins (rats,
chickens, human)
ROlHL-03429-18 Central nervous system and coronary
heart disease (human)
** ROlHL-05062-18 Lipid metabolism in cultured cells
(human, rats, rabbits)
ROlHL-06481-15 Lipid metabolism (human, rats)
R01HL-n90112 Effects of metabolic surgery on the
hyperlipidemias
Effects of metabolic surgery on
Partial ileal bypass (human)
Effects of metabolic surgery on
Ileal bypass -Cholesterol dynamics
studies (rats, rabbits, dogs)
ROIHL! 1901-12 0006 Effects of metabolic surgery on
Drug therapy with ileal bypass
M
R01HL-1190M2 0001
the hyperiipidemias -
ROlHL-11901-12 0004
the hyperlipidemias -
the hypertipidemias
(rabbits)
ROlHL-11901-12 0012
the hyperlipidemias
Effects of metabolic surgery on
Ileal bypass-Animal atherosclerosis
implications (pigeons, dogs, rabbits)
ROlHL-11901-12 0015 Effects of metabolic surgery on
the hyperlipidemias - Portacaval shunt for cholesterol
reduction (dogs, rabbits)
ROlHL-1 1901-12 0017 Effects of metabolic surgery on
the hypertipidemias - Membrane permeability, blood
viscosity, oxygen uptake-Rheology studies (rabbits)
ROlHL-12399-13 Specific fatty acids and cholesterol
metabolism (gerbils, rats)
R01HL12740-10 Hypocholesterolemic agents-
Stereochemistry (rats)
ROIHL-12745-10 Enzymes and inhibitors of cholesterol
biosynthesis (rats, human, swine)
322
P50HL-14164-07 0027 A/S SCOR -Comparative and
experimental atherosclerosis - Hyper- and
hyporesponsiveness to dietary cholesterol (squirrel monkey)
P50HL-14164-07 0028 A/S SCOR -Comparative and
experimental atherosclerosis - Hyper- and
hyporesponsiveness to dietary cholesterol (African green
monkey)
P50HL-14164-07 0030 A/S SCOR-Comparative and
experimental atherosclerosis - Morphology, angiochemistry-
Diet induced lesions in African green monkey
P50HL-14197 07 0006 Support for center of research on
arteriosclerosis - Diets and drugs affecting lipid
metabolism (human)
P50HL-14230-07 0088 A/S SCOR -Lipids, atherosclerosis
and thrombosis - Coronary risk factors in school children-
The Muscatine study
P50HL 14230-07 0093 A/S SCOR -Lipids, atherosclerosis
and thrombosis - Clinical studies involving cellular lipid
content (human)
P50HL 14230-07 0094 A/S SCOR-Lipids. atherosclerosis
and thrombosis - Studies of atherosclerosis and regression
(monkeys)
P50HL 14236-05 0001 Prevention of premature
arteriosclerosis - Metabolism and transport of cholesterol
and vitamin A (human, rats)
P50HL-I4236-05 0005 Prevention of premature
arteriosclerosis - Genetically hypertipidemic and
hypolipidemic rats
POlHL-14388-07 0165 Regulation of the circulation in
pathological states - Vascular resistance in experimental
atherosclerosis in Rhesus monkeys
P50HL-1 51 03-07 0013 A/S SCOR-Early natural history of
arteriosclerosis - Experimental models of atherosclerosis
(monkeys)
ROlHL-15448-Oe Surgical and metabolic aspects of
venous grafts, (dogs, monkeys, rabbits)
ROlHL-164 19-03 Arterial uptake of lipoprotein-Kinetic
analysis (rabbits)
ROlHL-16587-04 Cholesterol binding saponins and
atherosclerosis (monkeys)
P60HL-1 7269-04 0015 National heart and blood vessel
research and demonstration center - Lipoprotein
metabolism laboratory (human)
ROlHL-17463-03 Composition and structure of plasma
lipoproteins (human, rabbits)
ROlHL-17754-03 Pathogenesis and prevention of
hypertension sequelae (rats)
ROlHL-17882-04 Regulation of HMG-COA reductase and
sterol synthesis (human, mammals)
ROlHL-18085-03 Neural factors in atherogenesis (squirrel
monkeys)
ROlHL-18152-03 Vascular injury and atherosclerosis
(mice, coxsackievirus)
ROlHL-18636-02 Fatty acids and cholesterol transport
(rats)
POlHL-18645-03 0001 Biology of the artery wall and
atherosclerosis - Primate arterial smooth muscle and
atherosclerosis
POlHL-18645-03 0005 Biology of the artery wall and
atherosclerosis - Effects of atherosclerosis risk factors on
endothelium of the primate
POlHL-18645-03 0006 Biology of the artery wall and
atherosclerosis - The platelet and atherosclerosis (monkeys,
baboons)
POlHL-18645-03 0007 Biology of the artery wall and
atherosclerosis - Lipoprotein metabolism in subhuman
primates
P50HL-18828-03 0006 Specialized center of research in
thrombosis - Etiology and pathogenesis of atherosclerosis
(rabbit, monkey, rat, human)
ROlHL-18878-03 Familial hypercholesteremia -Studies of
fibroblasts (human)
ROlHL-191 75-03 Pituitary modulation of micro-and macro-
vascular disease (human, rats)
ROlHL-19223-03 Control of cholesterogenesis in leukocytes
and liver (rats, human)
P50HL-19362-02 0003 A/S SCOR-Atherosclerosis in
nonhuman primates ■ Heritability of characters related to
atherosclerosis (baboons)
P50HL-19362-02 0004 A/S SCOR-Atherosclerosis in
nonhuman primates - Selective breeding for characters
related to atherosclerosis (baboons)
P50HL-19362-02 0005 A/S SCOR-Atherosclerosis in
nonhuman primates - Hybridization to produce primate
model of atherosclerosis (baboon. Rhesus)
ROlHL-20397-03 VLDL-TG metabolism in diabetes mellitis
(human, rat)
ROlHL-20807-02 Detection of familial hypercholesterolemia
(human)
ROlHL-20924-02 Atherosclerosis and arterial cell functions
(human, rabbits)
POlHL-20993-02 0001 Population dynamics of arterial
cells in atherogenesis - Arterial SMC population dynamics
in atherogenesis (swine)
POlHL-20993-02 0007 Population dynamics of arterial
cells in atherogenesis - Interaction of lipoproteins in
hypercholesteremia (human, swine)
P50HL-21006-02 0001 Specialized center of research in
arteriosclerosis - Clinic and core program
P50HL-2 1006-02 0002 Specialized center of research in
arteriosclerosis - Turnover and metabolism of cholesterol in
man
LIP
Glycemia, other traits and CV death in
Genetic patterns in deaths from Ml and
Behavioral changes in post infarction
Transport of LDL in arterial wall (human.
'Excludes routine methodology OR covers only general projects which preclude indexing
"Oriented significantly to above subject.
at the specific level.
ROlHL-21010-02
40,000 persons
R01HL-2I088-02
stroke in Utah
ROlHL-21427-02
patients
ROlHL-21429-02
mammals)
ROlHL-2 1438-02 Structure and permeability of arterial
endothelium (pigs)
ROlHL-21460-02 Lipoproteins, hemostasis and
atherosclerosis (human, rabbits)
ROlHL-21756-11 Vascular disease-Cytochemistry and
ultrastructure (human, rats, mice, hamsters)
ROlHL-2 1764-01 Ultramicroanalysis of prostaglandins and
related compounds (rats)
R01HL-22748-0I Effect of bile sequestration on VLDL
metabolism (human)
ROlHL-23945-06 Pathologic effects on cells of modified
lipoproteins (rats, human)
NOlHV-22971-07 Prevention of coronary heart disease
(human)
NOlHV-22976-07 Multiple risk factor intervention trial.
prevention of coronary heart disease
NOlHV-22977-08 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22979-07 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22980-06 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22981-10 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22982-07 Intervention trial for prevention of
coronary heart disease (human)
NOlHV-22983-07 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-33 101-06 Development and conduct of a multiple
risk factor intervention trial (human)
NOlHV-33105-09 Intervention trial for prevention of
coronary heart disease (human)
NO lHV-33 106-06 Intervention trial for the prevention of
coronary heart disease (human)
NO lHV-33 108-04 Prevention of coronary heart disease
(human)
NO lHV-33 109-04 Intervention trial for the prevention of
coronary heart disease (human)
NOIHV-33110-04 Prevention of coronary heart disease
(human)
LIPIDS BLOOD, HYPERCHOLESTEREMIA
ESSENTIAL FAMILIAL
SEE METABOLIC DISORDERS INBORN,
HYPERLIPOPROTEINEMIAS FAMILIAL. TYPE II
LIPIDS BLOOD, HYPERLIPEMIA
SEE ALSO LIPIDS BLOOD. HYPERCHOLESTEREMIA
SEE ALSO LIPOPROTEINS BLOOD. HYPERLIPOPROTEINEMIA
ROlHL-01803-23 0005 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Immunologic and dietary synergy in the
pathogenesis of atherosclerosis (rabbits)
ROlHL-01803-23 0011 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Immunopathologic consequences of
cigarette smoking (human, rabbits, plants)
ROlHL-01979-22 Arteriosclerosis in zoo animals on
controlled diets (animals)
** ROlHL-02965-22 Metabolism of plasma lipoproteins (rats,
chickens, human)
ROlHL-05209-18 Lipid metabolism (monkeys)
** ROlHL-06222-18 Clinical and laboratory studies in lipid
metabolism (human, mammals, non-human)
POlHL-06285-18 0204 Cardiovascular-respiratory
physiology and biochemistry - Lipoprotein lipase and
triglyceride transport in chylomicrons (guinea pig. rat)
POlHL-06835-17 0015 Cardiovascular disease - Plasma
cholesterol esterification in canine athenisclerosis
** POlHL-06835-17 0022 Cardiovascular disease - Arterial
lipogenesis from glucose in the rat
** POlHL-06835-17 0063 Cardiovascular disease - Studies
on prostaglandins (human, rabbits)
** ROlHL-08506-15 Lipemia-carbohydrate and glyceride
metabolism (human, rats)
" ROlHL-09622-14 Pathogenesis of atherosclerosis (rats)
ROlHL-09744-14 Experimental vascular sclerosis
(monkeys, rabbits)
ROlHL-10316-13 Structural studies on low density serum
lipoproteins (human)
ROlHL-11775-11 Platelet mechanisms in disease (human,
primates)
M R01HL11901-12 Effects of metabolic surgery on the
hypertipidemias
Effects of metabolic surgery on
Partial ileal bypass (human)
Effects of metabolic surgery on
Ileal bypass-Cholesterol dynamics
studies (rats, rabbits, dogs)
ROlHL-11901-12 0013 Effects of metabolic surgery on
the hypertipidemias - Human cholesterol and bile acids
dynamics-lleal bypass
ROlHL-12085-10 Lipoprotein-carbohydrate metabolism
(human, rats)
ROlHL-1274010 Hypocholesterolemic agents-
Stereochemistry (rats)
(contd)
ROlHL-11901-12 0001
the hypertipidemias -
ROlHL-11901-12 0004
the hypertipidemias -
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
UP
R01H11276609 Structure lunclion lelation ol blood
vessels (tatsc monkeys)
PbOHL 14141 Ob 0001 SCOR lor etherosclerosis in
childhood Clinical implications (inlanis and children)
•• P50HI 14141 05 0003 SCOR tor atherosclerosis in
childhood Detection ol abnormalities in lipid metabolism
(human, rabbits, rats)
•• PMHL 14197 0/ 0006 Support lor center ot research on
arteriosclerosis Diets and druBS attecting lipid
metabolism (human)
•• PSOHl. 14?3007 0088 A/S SCOR Lipids, atherosclerosis
and thrombosis Coronary risk factors in school children-
The Muscatine study
•• P50HL1423007 0093 A/S SCOR-Lipids, atherosclerosis
and thrombosis Clinical studies involving cellular lipid
content (human)
M P50HL 1423605 Prevention of premature arteriosclerosis
P50H114236 05 0001 Prevention ot premature
aiteriosclerosis ■ Metabolism and transport ot cholesterol
and vitamin A (human, rats)
** P50HL1423605 0003 Prevention ol premature
artenosclerosis Intravascular clotting in patients with
hyperlipidemia
*♦ P50HL-142360S 0005 Prevention of premature
arteriosclerosis - Genetically hyperlipidemic and
hypolipidemic rats
** P50HI-1423605 0006 Prevention of premature
arteriosclerosis Carbohydrate metabolism and
hypertriglyceridemia (human)
** P50HL14236-05 0009 Prevention of premature
arteriosclerosis - Clinical studies on cholesterol metabolism
(human)
P50m.l423605 0010 Prevention of premature
arteriosclerosis ■ Computer programs
** P50HL- 1423605 0011 Prevention of premature
arteriosclerosis - Nutritional program
P50H114237 07 0001 Support for arteriosclerosis center
■ Role of apolipoproteins in lipoprotein catabolism (human,
rats)
** R01HL1437807 Lipemias and reconstructive cardiac
surgery (human)
ROlHl.14781-08 Lipid deposition in mammalian cells
(mice)
P50HL-15062-07 0012 Study of lipoproteins, artery wall,
and atherosclerosis - Lipoprotein stimulation of arterial
smooth muscle cell proliferation (mammals)
P50HL1506207 0018 Study of lipoproteins, artery wall,
and atherosclerosis ■ Reversal of atherosclerosis in
monkeys
P50HL15062-07 0019 Study of lipoproteins, artery wall,
and atherosclerosis ■ Factors regulating lipoprotein-smooth
muscle cell interaction (monkey)
•* P50HL-1 5062-07 0020 Study of lipoproteins, artery wall,
and atherosclerosis - Artery wall reactions-Elevated
pressure and hyperlipemia (monkey)
R01HL15448-06 Surgical and metabolic aspects of
venous grafts, (dogs, monkeys, rabbits)
P01HL1559605 0002 Coagulation, fibrinolysis,
hemostasis and hepatitis - Radioimmunoassay of
fibrinogen and fibrin derivatives (human)
ROlHL-15895-05 In vitra study of lipoproteins in vascular
disease (human, animals)
ROlHL-15949-05 Lipoprotein metabolism in relation to
atherosclerosis (human, baboons)
R01HL-16206-04 Regression of atherosclerotic plaques
(monkeys, dogs)
*♦ R01HL16219-05 Klechanisms of atherogenesis in chronic
uremia (human, rats)
R01HL16577-04 Lipoprotein lipase chemistry and function
(rats, cattle, human)
ROlHL-16588-05 Collagen synthesis in atherosclerosis
(dogs, rats, rabbits, human)
ROlHL-17332-04 Use of the gut for therapy of coronary
artery disease (mammals)
ROlHL-1 7369-04 Arterial bypass surgery -Structure and
metabolism (monkeys)
ROlHL-17818-05 Metabolism of cholesterol and cholesterol
in man (also rats, monkeys)
** ROlHL-18152-03 Vascular injury and atherosclerosis
(mice, coxsackievirus)
ROlHL-1862503 Organization of arterial ground substance
(cattle)
" ROlHL-18712-03 Iron deficiency-hyperlipidemia in
development (rats)
POlHL-18827-02 0001 Platelet vessel wall interactions in
thrombogenesis - Role of endothelial cells in the production
of thrombi (human, cattle)
** ROlHL-18923-02 Steroid-induced hyperlipidemia and
hypertension (human, rats)
** ROlHL-19175-03 Pituitary modulation of micro-and macro
vascular disease (human, rats)
R01HL-19974-02 Psychologic-behavioral influences on
heart pathology (rats)
ROlHL-20124-02 Coronary risk factors (human)
** ROlHL-20183-02 Portacaval shunt as treatment for
hyperlipemia (pigs)
ROlHL-20397-03 VLOL-TG metabolism In diabetes mellitis
(human, rat)
** ROlHL-20408-03 Hyperlipidemia in diabetics during
muscular training (human)
ROlHL-20418-03 Serum cholesterol binding reserve in
diabetes (human)
323
ROIHL 20488 03 Cholesterol metabolism in diabetic man
ROltU 20807 0? Detection of familial hypercholesterolemia
(human)
ROIHI 20910 02 The alternative diet lor coronary disease
prevention (human)
"* POIHL 20948 02 0001 Molecular basis ol cholesterol
metabolism Biochemical and ultrastructural
characterisation ol LDL in human fibroblasts
M P50HL 21006-02 Specialized center ol research in
arteriosclerosis
" P50HL 21006 02 0001 Specialized center of research in
arteriosclerosis Clinic and core program
** P50HL 21006 02 0002 Specialized center of research in
arteriosclerosis Turnover and metabolism of cholesterol in
man
P50HI-21006-02 0005 Specialized center of research in
arteriosclerosis Regional myocardial perfusion in patient
with coronary artery disease (also dogs)
** P50HL21006 02 0006 Specialized center of research in
arteriosclerosis Intravascular coagulation and thrombosis
in hyperlipidemia (human)
ROIHL 221 15-02 Lipid-mobilization and diabetic
atherosclerosis (human)
ROlHL-22121-02 Oyslipoproteinemia in diabetes and
vascular disease (human)
R01HL-22255-01 The etiology/prevalence of peripheral
arterial disease (human)
** ROlHL-22341-01 Pathogenesis of atherosclerosis in rats
ROlHL-22367-Ol Estrogen receptors in very low density
lipoproteins (chicken livers)
ROlHL-22456-01 Lipoproteins in bioregulation of the
immune response (mice, human)
ROlHL-22567-01 Validation of a cholesterol absorption
method in man
** POlHL-22602-01 0004 Pathophysiology of the
endothelium - Endothelium, platelets smooth muscle and
atherosclerosis (rabbits)
ROlHL-22607-01 Role of apolipoprotein E in lipoprotein
metabolism (human)
** POlHL-22633-01 0001 Cellular and molecular biology of
lipoprotein metabolism Secretion of lipoproteins by the
perfused liver (rats, rabbits)
POlHL-22633-01 0002 Cellular and molecular biology of
lipoprotein metabolism - Sterol metabolism in tissue
culture cells
ROlHL-22847-01 Test for adherence to diets rich in
linoleic acid
ROlHL-231 59-01 Regulation of lipogenesis by
polyunsaturated fats (rats, chicks)
R01HL-23945-06 Pathologic effects on cells of modified
lipoproteins (rats, human)
** NOlHV-72983-00 Nutrition counseling in hyperlipidemia
LIPIDS BLOOD, HYPOCHOLESTEREMIA
P50HL 14236-05 0005 Prevention of premature
arteriosclerosis - Genetically hyperlipidemic and
hypolipidemic rats
LIPIDS METABOLISM
SEE ALSO FATTY ACIDS METABOLISM
SEE ALSO LIPID MOBILIZING FACTORS
SEE ALSO STEROID METABOLISM
ROlHL-01803-23 0005 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Immunologic and dietary synergy in the
pathogenesis of atherosclerosis (rabbits)
** ROlHL-024 77-23 Biosynthesis and function of lipids
(microorganisms, rats)
•* ROlHL-05062-18 Lipid metabolism in cultured cells
(human, rats, rabbits)
** ROlHL-05209-18 Lipid metabolism (monkeys)
** ROlHL-06222-18 Clinical and laboratory studies in lipid
metabolism (human, mammals, non-human)
POlHL-06285-18 0205 Cardiovascular-respiratory
physiology and biochemistry - Assimilation of cholesterol in
chylomicrons and VLDL (rabbits)
** POlHL-0630818 0040 Mechanisms and therapy of
circulatory disease - Metabolism and fatty acid utilization-
Heart electrical stability (rats, dogs)
'* POlHL-063 12-17 0046 Surgical cardiology - The
relationship of prostaglandins to heart disease
** POlHL-06835-17 0016 Cardiovascular disease - Metabolic
interactions to polyunsaturated fatty acids in atherogenic
diet (dogs)
** POlHL-06835-17 0020 Cardiovascular disease - Lipid
metabolism (rats)
** POlHL-06835-17 0064 Cardiovascular disease - Studies
in atherosclerosis (human, animals)
M POlHL-082 14-15 Chemical and biological properties of
lipids
** POlHL-082 14-15 0005 Chemical and biological properties
of lipids - Metabolism of lipids in animals
** POlHL-082 14-15 0023 Chemical and biological properties
of lipids - Lipids in microorganisms and cell cultures
(hamsters, mosquitoes)
** POlHL-08214-15 0027 Chemical and biological properties
of lipids - Biological functions did lipids (swine, rats,
plants)
** POlHL-082 14-15 0041 Chemical and biological properties
of lipids - Physico-chemical regulation of enzymes in lipid
metabolism
** POlHL-082 14-15 0048 Chemical and biological properties
of lipids - Lipids in microorganisms and plants
UP
ROIHI 08506 15 lipomia carbohydtal* and ilyceride
metabolism (human, rats)
ROIHI 08634 15 fn/ymic cholesterol synthesis (human.
rats, protozoa, yeast)
** ROIHI 08659 14 Myocardial performance and metabolism
in the newborn (sheep)
M POIHI 08974 14 Natural and ciperimental atherosclerosis
** POIHL 08974 14 0024 Natural and eiperimental
atherosclerosis Atherosclerosis, sterol and lipoprotein
metabolism in nonhuman primates
•* ROIHL 09489 13 Myocardial lipid metabolism and
regulation (rats)
ROIHL 09744 14 Experimental vascular sclerosis
(monkeys, rabbits)
ROIHI 10018 11 Effect ol aging on beating heart cells in
culture (rats)
*• ROIHI 10933-13 Fat metabolism and atherosclerosis
(rabbits, cattle, human, rats)
POlHL-11310-12 0101 Mechanisms of cardiovascular
disease Molecular pathogenesis of vascular disease
ROlHL-12138-08 Nutritional regulation of enzyme activity
(rats, human)
** ROlHL-12399 13 Specific fatly acids and cholesterol
metabolism (gerbils, rats)
ROlHL-12766 09 Structure function relation of blood
vessels (rats, monkeys)
ROlHL-12869-09 Arterial metabolism, diabetes and
atherogenesis (rats, rabbits)
ROIHL 13257-09 Inhalation anesthesia on myocardial
metabolism (dogs, swine, human)
** POIHL 13262 07 0016 Arterial wall in atherosclerosis
Lipids in elastin preparations from atherosclerotic plaques
(human, animals)
** ROlHL-1330209 Uptake and metabolism of lipids by the
liver (rats)
** ROIHL- 13405-09 Regulation of lipid metabolism m the
lung (rats)
** P50HL 14164-07 0035 A/S SCOR -Comparative and
experimental atherosclerosis - Lipid metabolism -Interaction
with arterial metabolism (monkey, pigeon)
P50HL 14164-07 0036 A/S SCOR -Comparative and
experimental atherosclerosis - Connective tissue
metabolism -Interaction with arterial metabolism (monkeys)
M P50HL-14197-07 Support for center of research on
arteriosclerosis
** P50HL-14197-07 0005 Support for center of research on
arteriosclerosis - Lipoprotein biosynthesis and degradation
in vivo and in vitro (human, animal)
** P50HL-14197-07 0006 Support for center of research on
arteriosclerosis - Diets and drugs affecting lipid
metabolism (human)
** P50HL-1419707 0007 Support for center of research on
arteriosclerosis - Metabolic defects in familial
hyperlipoproteinemias (human)
•* P50HL- 14230-07 0092 A/S SCOR-Lipids, atherosclerosis
and thrombosis • Tissue lipids -Cell culture studies
(human)
** P50HL-14237-07 0002 Support for arteriosclerosis center
- Interactions of lipoprotein particles with vascular surface
(human, rat)
ROlHL-14313-07 Apoproteins of triglyceride rich
lipoproteins (human, squirrel monkeys, rats)
" ROlHL-14781-08 Lipid deposition in mammalian cells
(mice)
ROlHL-15263-06 Lecithin -Cholesterol acetyltransferase
(human, rabbits)
ROlHL-15273-06 Metabolism of pulmonary surfactant
(human, rats)
** ROlHL-15448-06 Surgical and metabolic aspects of
venous grafts, (dogs, monkeys, rabbits)
ROlHL-15504-05 Animal model for studies on averting
atherosclerosis (swine)
** ROIHL- 15646-03 Lipid studies in vascular smooth muscle
cells (human, monkeys)
** ROlHL-15648-06 Lipid metabolism-Transport by lateral
diffusion (human, rabbit, cattle)
** ROlHL-15797-05 Lipid metabolism and atherosclerosis in
primates (monkeys, human, squirrels)
ROlHL-16206-04 Regression of atherosclerotic plaques
(monkeys, dogs)
R01HL-16219-05 Mechanisms of atherogenesis in chronic
uremia (human, rats)
** ROlHL-16364-04 Regulation of lipid biosynthesis and
transport (rats, swine, Xenopus)
** ROlHL-16628-05 Regulation of lipid metabolism (rats)
** ROlHL-16955-05 Heparin, blood coagulation and lipid
metabolism (human)
** ROlHL-17332-04 Use of the gut for therapy of coronary
artery disease (mammals)
** ROlHL-17369-04 Arterial bypass surgery-Structure and
metabolism (monkeys)
" R01HL-17564-03 Unsaturated fats-Mode of
hypocholesterolemic action (minipig)
P50HL-17546-04 0005 Study of ischemic heart disease -
Biochemical markers and mediators of myocardial ischemic
injury
** P50HL-1764804 0027 Study of ischemic heart disease -
Phospholipid metabolism following cardiac injury and
repair (rat)
R01HL18085-03 Neural factors in atherogenesis (squirrel
monkeys)
(contd)
•Excludes routine methodology OR covers only general projects which preclude Indexing at the specific level.
•*Orierted significanthl to above subject.
M Grant has subprajects describing specific research aspects.
See Appendix for investigator's name and grant number.
LIP
* R01HL18157-04 Subcellular events in atherosclerosis
(human, rabbits, calves)
P50HL-183 18-03 0014 Pathogenesis and complications of
hypertension ■ Arterial metabolism and atherogenesis (rat,
rabbit)
P50HL-18318-03 0015 Pathogenesis and complications of
hypertension - Cultured smooth muscle cells and
microvessel metabolism (mammals)
POlHL-18574-03 Lipoprotein methodology and biomedical
applications
P01HL18574-03 0001 Lipoprotein methodology and
biomedical applications - Ultracentrifugal and
electrophoretic lipoprotein methodology-Applications
' POlHL-18574-03 0004 Lipoprotein methodology and
biomedical applications - Fine structure and metabolism of
lipoproteins-EM studies (guinea pigs)
• POlHL-18574-03 0005 Lipoprotein methodology and
biomedical applications - Structure and function of
lipoproteins
' POlHL-18574-03 0006 Lipoprotein methodology and
biomedical applications - Lipoprotein transformation,
lipolytic enzymes, diet and lipid lowering agents
POlHL-18577-03 0001 Lipoproteins -Cell surface
interactions - Structural studies of serum lipoproteins in
man and dogs
■ ROlHL-18586-03 Role of platelet lipids In hemostasis and
thrombosis (human)
POlHL-18645-03 0001 Biology of the artery wall and
atherosclerosis - Primate arterial smooth muscle and
atherosclerosis
POlHL-18645-03 0004 Biology of the artery wall and
atherosclerosis - Human arterial smooth muscle cell and
lipoprotein interaction
' POlHL-18645-03 0007 Biology of the artery wall and
atherosclerosis - Lipoprotein metabolism in subhuman
primates
ROlHL-1871203 iron deficiency-hyperlipidemia in
development (rats)
POlHL-18827-02 0001 Platelet vessel wall interactions in
thrombogenesis - Role of endothelial cells in the production
of thrombi (human, cattle)
■ ROlHL-1901003 Metabolism and cell biology of lung
surfactant system (rabbits, sheep)
ROlHL-19175-03 Pituitary modulation of micro-and macro-
vascular disease (human, rats)
P50HL-1936202 0001 A/S SCOR-Atherosclerosis in
nonhuman primates - Effects of infant nutrition on
atherosclerosis (baboons)
P50HL-19362-02 0002 A/S SCOR-Atherosclerosis in
nonhuman primates - Infant caloric intake, adipose tissue
development and atherosclerosis (baboon)
P50HL-1936202 0005 A/S SCOR-Atherosclerosis in
nonhuman primates - Hybridization to produce primate
model of atherosclerosis (baboon. Rhesus)
' P50HL-I9362-02 0013 A/S SCOR-Atherosclerosis in
nonhuman primates - Core laboratory -Lipid biochemistry
(baboons)
' ROlHL-20397-03 VLDL-TG metabolism in diabetes mellitis
(human, rat)
ROlHL-2040803 Hyperlipidemia in diabetics during
muscular training (human)
ROlHL-20483-03 Sterol balance and cholesterol absorption
in diabetics (human)
ROlHL-20954-02 Hyperlipoproteinemia (rats, human)
R23HL-21251-01 Metabolism of neutral lipids in the
pulmonary alveolus (rabbits)
ROlHL-21416-02 Atherosclerosis in new modles of
diabetes mellitus
ROlHL-2151302 Metabolism of trans fatty acids (human,
rats, swine)
ROlHL-22053-02 The disordered lipid metabolism of
diabetes mellitus (chickens, mammals, human)
ROlHL-22121-02 Dyslipoproteinemia in diabetes and
vascular disease (human)
ROlHL-22123-02 The role of the red cell in diabetic
atherosclerosis (human)
ROIHL-22502-01 Role of phosphoinositides in human
platelet secretion
POlHL-22619-01 Cellular mechanisms of heart failure
POlHL-22619-01 0011 Cellular mechanisms of heart
failure - Reaction of lipoproteins and apolipoproteins with
lipoprotein lipase (cattle)
POlHL-22619-01 0012 Cellular mechanisms of heart
failure - Apolipoproteins in hypertriglyceridemia (human)
POlHL-22633-01 Cellular and molecular biology of
lipoprotein metabolism
POlHL-22633-01 0001 Cellular and molecular biology of
lipoprotein metabolism - Secretion of lipoproteins by the
perfused liver (rats, rabbits)
POlHL-22633-01 0002 Cellular and molecular biology of
lipoprotein metabolism - Sterol metabolism in tissue
culture cells
POlHL-22633-01 0003 Cellular and molecular biology of
lipoprotein metabolism - Sterol metabolism in platelets and
megakaryocytes (human, rabbits, guinea pigs)
ROlHL-22739-01 Evolution and progression of pediatric
atherosclerosis
ROlHL-22748-01 Effect of bile sequestration on VLDL
metabolism (human)
ROlHL-23161-01 0001 Biology of myocardial ischemia •
Mitochondrial lipid metabolism and cardiac ischemia (rat,
dog)
324
ROlHL-23598-01 Dietary fat, cholesterol and bile acid
turnover (rats)
ROlHL-236 18-01 Substrate metabolism in isolated
myocytes in shock (dogs, rats, guinea pigs)
ROlHL-23945-06 Pathologic effects on cells of modified
lipoproteins (rats, human)
ROlHL-2398101
NOlHV-12157-14
NOlHV-12158-10
NOlHV-22913-09
NOlHV-53029-04
atherosclerosis
NOlHV-53030-05
Acute alveolar injury (dogs)
Lipid research clinic (human)
Establishment of a lipid research clinic
Lipid research clinic
Nonhuman primate models of
Nonhuman primate models of
atherosclerosis and hypertension
NOlHV-53031-04 Nonhuman primate models of
atherosclerosis and hypertension
N01HV-72978-02 Development of models of hypertension
N01HV-72980-02 Development of models of hypertension
LIPIDS METABOLISM, UPOGENESIS
SEE ALSO FATTY ACIDS BIOSYNTHESIS
SEE ALSO STEROIDOGENESIS
ROlHL-01770-26 Structural aspects of lung surfactant
system (rats)
** ROlHL-02477-23 Biosynthesis and function of lipids
(microorganisms, rats)
POlHL-06285-18 0208 Cardiovascular-respiratory
physiology and biochemistry - Composition, properties and
turnover of pulmonary surfactant (human, animals)
** ROlHL-06481-15 Lipid metabolism (human, rats)
"* P01HL-06835-17 0022 Cardiovascular disease - Arterial
lipogenesis from glucose in the rat
POlHL-0683517 0024 Cardiovascular disease - Studies
on the obese spontaneously hypertensive rat
" POlHL-082 14-15 0005 Chemical and biological properties
of lipids - Metabolism of lipids in animals
** POlHL-082 14-15 0025 Chemical and biological properties
of lipids - Biosynthesis and biological functions of
plasmalogen (cattle)
POlHL-0821415 0027 Chemical and biological properties
of lipids - Biological functions diol lipids (swine, rats,
plants)
POlHL-082 14-15 0030 Chemical and biological properties
of lipids - Fatty acid biosynthesis in plant cell cultures and
in plants
ROlHL-08506-15 Lipemia-carbohydrate and glyceride
metabolism (human, rats)
** ROlHL-11901-12 0004 Effects of metabolic surgery on
the hyperlipidemias - Ileal bypass -Cholesterol dynamics
studies (rats, rabbits, dogs)
ROlHL-12650-08 Environmental pathobiology of the lung
(hamsters, rats)
ROlHL-13028-09 Regulation of myocardial fatty acid
metabolism (rats)
** P50HL-14141-05 0003 SCOR for atherosclerosis in
childhood - Detection of abnormalities in lipid metabolism
(human, rabbits, rats)
" P50HL14214-07 0015 Newborn lung center for hyaline
membrane disease - Hormone effect on cyclic nucleotide
lipid synthesis in developing lung (animal)
P50HL-142 14-07 0021 Newborn lung center for hyaline
membrane disease - Development of surfactant system-
Surfactant production and release (rat, rabbit)
P50HL-1421407 0022 Newborn lung center for hyaline
membrane disease - Functional integrity of surfactant
system-Hyaline membrane disease (lamb, rat)
P50HL-14230-07 0093 A/S SCOR -Lipids, atherosclerosis
and thrombosis - Clinical studies involving cellular lipid
content (human)
P50HL14236-05 0002 Prevention of premature
arteriosclerosis - Myocardial blood flow in patients with
coronary arthcrosclerosis
P50HL-14236-05 0004 Prevention of premature
arteriosclerosis - Plasma lipoproteins (human, rats)
** P50HL-14237-07 0004 Support for arteriosclerosis center
- Synthesis, secretion of normal, abnormal plasma
lipoproteins (rodents, monkeys)
ROlHL-14990-07 Lipid transport in avian species
(chickens)
ROlHL-15013-07 Lung oxidative metabolism and energy
production (rodents, rabbits)
P50HL15061-07 0002 Response of lung to injury -
Oxidative metabolism, phospholipid synthesis, and response
to toxins (rats)
P50HL-1 5062-07 0009 Study of lipoproteins, artery wall,
and atherosclerosis - Plasma lipoprotein biosynthesis
(Rhesus monkeys)
** ROIHL-15476-05 Mechanism and control of sterol
biosynthesis (rats)
** ROlHL-15930-06 Hormonal control of lipid and lipoprotein
synthesis (rats)
POlHL-16137-05 0004 Alveolar biology - Subcellular
processes and controls in the surfactant system (animals)
ROlHL-162 19-05 Mechanisms of atherogenesis in chronic
uremia (human, rats)
** ROlHL-16364-04 Regulation of lipid biosynthesis and
transport (rats, swine, Xenopus)
** P60HL-1 7269-04 0045 National heart and blood vessel
research and demonstration center - Regulation of
lipogenesis in hyperlipoproteinemia (human, tissue culture)
" P50HL-1764804 0027 Study of ischemic heart disease ■
Phospholipid metabolism following cardiac injury and
repair (rat)
LIP
ROlHL-18239-03 Dietary fat composition and
prostaglandin synthesis (rats)
ROlHL-19056-03 Blood triglycerides and lipoprotein lipase
in the lung (rats)
ROlHL-19 168-03 Biosynthesis of plasma lipoprotein (rats,
rabbits)
P50HL-19185-02 0001 Pulmonary SCOR -Neonatal
respiratory distress syndromes Sites of synthesis,
secretion and structure of surface active material (rat)
P50HL-1918702 0002 Pediatric pulmonary SCOR-Hyaline
membrane disease - Hyaline membrane disease -Alterations
in surface active material (monkeys)
P50HL19187-02 0004 Pediatric pulmonary SCOR-Hyaline
membrane disease Hyaline membrane disease -Surface
active material, lamellar bodies (mice, rats)
P50HL-19190-02 0003 Pulmonary SCOR-Pathophysiology,
management of IRDS - Type II cells-Regulation and
differentiation (rat)
ROlHL-1922303 Control of cholesterogenesis in leukocytes
and liver (rats, human)
ROlHL-1966903 Lung organ culture and surfactant
biosynthesis (adult and fetal rats)
R01HL19752 03 Phospholipid synthesis by fetal lung in
organ culture (rats)
ROlHL-20183-02 Portacaval shunt as treatment for
hyperlipemia (pigs)
ROlHL-2048403 Effects of diabetes on cardiac function
and metabolism (rats)
Lactate metabolism In the lung (rats)
Effect of pollutants on organotypic lung
Effects of air pollutants on lung cells in
Biosynthesis of lung surfactant lipid
ROlHL-2056602
** ROlHL-21008-02
cultures (rats)
ROlHL-21009-02
culture (rats)
** ROlHL-21628-02
(rabbit)
ROlHL-22101-02 Hormone-substrate interaction in diabetic
myocyte (dogs, rats)
** ROlHL-22500-01 Conversion of choline to
phosphatidylcholine in lung (rabbits, pigs)
ROlHL-22502-01 Role of phosphoinositides in human
platelet secretion
ROlHL-22623-01 Polyamines cellular mediators of
atherogenesis (human)
ROlHL-22983-01 Studies on the catabolism of plasma
lipoproteins (rats)
** ROlHL-23159-01 Regulation of lipogenesis by
polyunsaturated fats (rats, chicks)
LIPIDS METABOLISM, LIPOLYSIS
SEE ALSO LIPID MOBILIZING FACTORS
ROlHL-02063-23 Biochemistry and function of lipids and
cell membranes (human, yeast, animals)
POlHL-1131012 0103 Mechanisms of cardiovascular
disease ■ Heparin-Meta holism and function
** POlHL-12373-10 0006 Cardiopulmonary physiology and
pathophysiology - Fatty acid metabolism-Regulation,
implications (human, mammals, birds)
** P01HL12373-10 0012 Cardiopulmonary physiology and
pathophysiology - Biochemistry of the sympathetic nervous
system (rats, rabbits, pigeons)
ROlHL-12740-10 Hypocholesterolemic agents-
Stereochemistry (rats)
R01HL13626-06 Lipoprotein lipase and lipoprotein
removal (human, rats, bacteria)
** P50HL-14237-07 0001 Support for arteriosclerosis center
- Role of apolipoproteins in lipoprotein catabolism (human,
rats)
POlHL-18577-03 0001 Lipoproteins-Cell surface
interactions - Structural studies of serum lipoproteins in
man and dogs
ROlHL-20484-03 Effects of diabetes on cardiac function
and metabolism (rats)
POlHL-22619-01 0011 Cellular mechanisms of heart
failure - Reaction of lipoproteins and apolipoproteins with
lipoprotein lipase (cattle)
** ROlHL-23142-01 Mechanisms of membrane injury in
myocardial ischemia (dog)
LIPIDS STRUCTURE
ROlHL-03299-21 Dietary effects on cholesterol metabolism
(rats, rabbits)
** POlHL-06285-18 0208 Cardiovascular-respiratory
physiology and biochemistry - Composition, properties and
turnover of pulmonary surfactant (human, animals)
** POlHL-0628518 0210 Cardiovascular-respiratory
physiology and biochemistry - Physicochemical and
enzymatic studies of lung surfactant (Halobacterium)
POlHL-09011-15 0005 A research and resource program
in blood - Characterization of hepatitis-B antigen and the
cause of serum hepatitis (human)
Myocardial lipid metabolism and
Effect of aging on beating heart cells in
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
••Qnented significantly to above subject.
ROlHL-09489-13
regulation (rats)
R01HL10018-11
culture (rats)
ROlHL-1411107 Cholesteryl esters in membranes and
atherosclerosis (human, swine)
P50HL-14147-08 0003 Specialized center of research in
thrombosis ■ Surface thrombogenicity and phospholipid
vesicle physical properties
P50HL-14147-08 0015 Specialized center of research in
thrombosis • Charge related properties of phospholipid
surfaces in monolayers and vesicles
(contd)
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
LIP
ROIHI 1537806 Ulttastructute ol antihypertensive
prostaglandins
ROIHI 1542706 Secretion ol plasma lipoproteins (rats)
ROIHI 1605906 Structure and lunction ol serum
lipoproteins (cattle, human)
•• ROIHI 16807 02 Lipid structure o( normal and
hypeilipoproteins (human)
R01HL17371 05 Regualtion ol cholesteryl ester levels in
the aorta (swine)
ROIHL 18623 12 Physical chemistry of biologically active
lipids (bacteria, plant, cattle, human)
•• ROIHL 1914803 Myocardial organelle lipid structure and
lunction (dog. rat)
ROIHL 1916803 Biosynthesis ot plasma lipoprotein (rats.
labbits)
ROIHL 1945903 Dynamics ot atherogenesis and
lipoprotein formation (human, rabbit)
ROIHL 2031702 Procoagulant hpuproteins Biochemistry
and bioactivity (goats, rabbits)
•* ROlHL-2035002 Crystal structure ot lipids Cholesterol
ROIHL 22052-01 Organization ot liee cholesterol in serum
lipoproteins (human, dogs)
ROlHL-2268201 Structure and function of high density
lipoprotein (human, rat)
R01HL-2300301 Bulk-surface distribution of cholesteryl
esters
ROlHL-23945-06 Pathologic effects on cells of modified
lipoproteins (rats, human)
LIPIDS TRANSPORT
SEE ALSO FAHY ACIDS TRANSPORT (GENERAL)
** ROlHL-01803-23 0014 Arteriosclerosis, glomerulonephritis,
rheumatic fever ■ Regenerated endothelium on lipid
accumulation in arterial wall (rabbit)
ROlHL-05209-18 Lipid metabolism (monkeys)
** R01HL06221-17 Composition and structure of plasma
lipoproteins (human, turkeys, baboons)
•* P01HL06285-18 0203 Cardiovascular-respiratory
physiology and biochemistry - Pathways of lipid transport
in the blood (animals)
** POlHL-06285-18 0204 Cardiovascular-respiratory
physiology and biochemistry - Lipoprotein lipase and
triglyceride transport in chylomicrons (guinea pig. rat)
** POlHL-06285-18 0205 Cardiovascular-respiratory
physiology and biochemistry - Assimilation of cholesterol in
chylomicrons and VLDL (rabbits)
** ROlHL-08634-15 Enzymic cholesterol synthesis (human,
rats, protozoa, yeast)
ROlHL-09739-13 Biophysical studies of proteins (human)
** R01HL-09744-I4 Experimental vascular sclerosis
(monkeys, rabbits)
ROlHL-10642-18 Plasma cholesterol metabolism (human,
macaca)
•* ROlHL-10940-13 Lipid transport (rabbits, cattle, chickens)
ROlHL-12399-13 Specific fatty acids and cholesterol
metabolism (gerbils, rats)
P50HL-14164-07 0033 A/S SCOR-Comparative and
experimental atherosclerosis • Comparative studies of
lipoprotein distribution and metabolism (monkeys)
P50HL-14230-07 0092 A/S SCOR -Lipids, atherosclerosis
and thrombosis • Tissue lipids -Cell culture studies
(human)
** P50HL-14236-05 0001 Prevention of premature
arteriosclerosis - li/letabolism and transport of cholesterol
and vitamin A (human, rats)
P50HL-14237-07 0004 Support for arteriosclerosis center
- Synthesis, secretion of normal, abnormal plasma
lipoproteins (rodents, monkeys)
** ROlHL-14990-07 Lipid transport in avian species
(chickens)
P50HL-1506207 0019 Study of lipoproteins, artery wall,
and atherosclerosis - Factors regulating lipoprotein-smooth
muscle cell interaction (monkey)
ROlHL-15478-05 Lipid flux and collagen synthesis in
atherosclerosis (rabbits)
ROlHL-15646-03 Lipid studies in vascular smooth muscle
cells (human, monkeys)
** ROlHL-15648-06 Lipid metabolism-Transport by lateral
diffusion (human, rabbit, cattle)
*• R01HL-16059-06 Structure and function of serum
lipoproteins (cattle, human)
ROlHL-16364-04 Regulation of lipid biosynthesis and
transport (rats, swine, Xenopus)
** R01HL-16419-03 Arterial uptake of lipoprotein-Kinetic
analysis (rabbits)
ROlHL-16577-04 Lipoprotein lipase chemistry and function
(rats, cattle, human)
P60HL-17269-04 0015 National heart and blood vessel
research and demonstration center - Lipoprotein
metabolism laboratory (human)
P60HL-17269-04 0045 National heart and blood vessel
research and demonstration center - Regulation of
lipogenesis in hypertipoprotememia (human, tissue culture)
ROlHL-18157-04 Subcellular events in atherosclerosis
(human, rabbits, calves)
** POlHL-18577-03 0003 Lipoproteins -Cell surface
interactions - l^echanism of lipid exchange in lipoproteins
and cell membranes
** POlHL-18577-03 0004 Lipoproteins-Cell surface
interactions - Analysis and chemical modification of
prote'ns in lipid transport (human, dogs)
** ROlHL-18636-02 Fatty acids and cholesterol transport
(rats)
325
P50HI 18828 03 0005 Specialized center of research in
thrombosis Etiology and pathogenesis ol atherosclerosis
(rabbit, monkey, rat, human)
ROIHI 20418 03 Serum cholesterol binding reserve in
diabetes (human)
ROIHL 2048803 Cholesterol metabolism in diabetic man
ROIHL 20882 02 Interactions of plasma lipoproteins with
erythrocytes (Rhesus, human)
P50HL 21006 02 0003 Specialized center of research in
arteriosclerosis Transport of vitamin A in plasma (human,
rat)
R23HL21271 02 Extracorporeal circulation and protein
denaturation (human)
R23HL2155901 Oxygen supply and blood flow through
aortic vasa vasorum (dogs)
ROIHL 21845-01
function
NOIHV 12160 15
NOIHV 5301509
(human)
Human red cell membrane -Structure and
Establishment of a lipid research clinic
Establishment of a lipid research clinic
UPOAMINO ACIDS
SEE PHOSPHOLIPIDS. PHOSPHOGLYCERIOES. PHOSPHATIDYL
SERINE
LIPOFUSCIN-CEROID
ROlHL-100 18-11 Effect of aging on beating heart cells in
culture (rats)
UPOGENESIS
SEE LIPIDS METABOLISM. LIPOGENESIS
UPOGENIC INHIBITORS
SEE ALSO CHOLESTANE SERIES. CHOLESTEROL INHIBITORS
R01HL03299-21 Dietary effects on cholesterol metabolism
(rats, rabbits)
ROlHL-05062-18 Lipid metabolism in cultured cells
(human, rats, rabbits)
R01HL10933-13 Fat metabolism and atherosclerosis
(rabbits, cattle, human, rats)
ROlHL-12085-10 Lipoproteincarbohydrate metabolism
(human, rats)
ROlHL-12740-10 Hypocholesterolemic agents-
Stereochemistry (rats)
ROlHL-1372208 Acid and alkaline lipases in aortas (rats,
rabbits, human)
" P50HL- 14 141-05 0003 SCOR for atherosclerosis in
childhood • Detection of abnormalities in lipid metabolism
(human, rabbits, rats)
P50HL-14197-07 0006 Support for center of research on
arteriosclerosis - Diets and drugs affecting lipid
metabolism (human)
R01HL15930-06 Hormonal control of lipid and lipoprotein
synthesis (rats)
** ROlHL-18887-03 Hypolipidemic drugs-Effects on FFA-
albumin association (human, cattle)
ROlHL-19820-02 The chemistry and biological effects of
heparin (Rhesus, human, other mammals)
** ROlHL-20909-02 Clofibrate-enhanced lipid oxidation by
peroxisomes (rats)
ROlHL-2095402 Hyperlipoproteinemia (rats, human)
P50HL-21006-02 0002 Specialized center of research in
arteriosclerosis - Turnover and metabolism of cholesterol in
man
ROlHL-21460-02 Lipoproteins, hemostasis and
atherosclerosis (human, rabbits)
ROlHL-23159-01 Regulation of lipogenesis by
polyunsaturated fats (rats, chicks)
LIPOGRANUIOMATOSES, CEREBROTENDINOUS
XANTHOMATOSIS
R01HL-1089412 Intestinal bacteria and steroid
metabolism (human, guinea pigs, rabbits, rats)
** R01HL-17818-05 Metabolism of cholesterol and cholesterol
in man (also rats, monkeys)
LIPOGRANUIOMATOSES, LIPOID PROTEINOSIS
ROlHL-12650-08 Environmental pathobiology of the lung
(hamsters, rats)
LIPOIC ACID
SEE VITAMIN B, LIPOIC ACID
LIPOID PROTEINOSIS
SEE LIPOGRANULOMATOSES, LIPOID PROTEINOSIS
LIPOIDAL DISORDERS
SEE ALSO BODY WEIGHT, OBESITY
SEE ALSO LIPIDS BLOOD, HYPERCHOLESTEREMIA
SEE ALSO LIPIDS BLOOD, HYPERLIPEMIA
SEE ALSO LIPIDS BLOOD, HYPOCHOLESTEREMIA
SEE ALSO LIVER DISORDERS, FATTY LIVER
SEE ALSO METABOLIC DISORDERS INBORN,
HYPERLIPOPROTEINEMIAS FAMILIAL
SEE ALSO METABOLIC DISORDERS INBORN, LCAT DEFICIENCY
SEE ALSO METABOLIC DISORDERS INBORN, LIPID (NEUTRAL)
STORAGE
SEE ALSO METABOLIC DISORDERS INBORN, OBESITY
HEREDITARY HYPERGLYCEMIC
ROlHL-12869-09 Arterial metabolism, diabetes and
atherogenesis (rats, rabbits)
ROlHL-143 13-07 Apoproteins of triglyceride rich
lipoproteins (human, squirrel monkeys, rats)
ROlHL-15263-06 Lecithin-Cholesterol acetyltransferase
(human, rabbits)
UP
ROIHI 1815/04 Subcellular events in ath*roicl«ro(ll
(human, rabbits, calves)
•• ROIHI 18623 12 Phyiiial chemistry of biologically active
lipids (bacteria, plant, cattle, human)
ROIHI 20622 02 Pulmonary uptake and accumulation of
drugs (rabbits, rats)
ROIHL 21/56 11 Vascular disease Cytochemistry and
ultrastructure (human, rats. mice, hamsters)
ROIHL 22121 02 Dyslipoproteinemia in diabetes and
vascular disease (human)
ROlHt 2394506 Pathologic effects on cells ol modified
lipoproteins (rats, human)
LIPOIDAL DISORDERS, XANTHOMATOSIS
SEE ALSO METABOLIC DISORDERS INBORN, LIPID (NEUIRAL)
STORAGE, WOLMANS DISEASE
ROIHL 1887803 Familial hypercholesteremia -Studies of
fibroblasts (human)
LIPOLYSIS
SEE LIPIDS METABOLISM, LIPOLYSIS
LIPOLYTIC HORMONES (PITUITARY)
SEE LIPID MOBILIZING FACTORS PITUITARY
LIPOPOLYSACCHARIDES
SEE POLYSACCHARIDES. LIPOPOLYSACCHARIDES
LIPOPROTEIN LIPASE
SEE LIPASES. LIPOPROTEIN LIPASE
LIPOPROTEINS
SEE ALSO LIPASES, LIPOPROTEIN LIPASE
SEE ALSO LIPIDS, CHYLOMICRONS
SEE ALSO PROTEOLIPIDS
R01HL0I803-23 0014 Arteriosclerosis, glomerulonephritis,
rheumatic fever Regenerated endothelium on lipid
accumulation in arterial wall (rabbit)
P01HL03174-23 0010 Mechanisms of acute vascular
reaction to injury Search for mutagens in the human
blood (bacteria, animals)
ROlHL-05556-19 Proteins, lipoproteins-Structure and
reactivity (chicken, human, diving mammals)
P01HL-06835-17 0021 Cardiovascular disease • Animal
study in atherosclerosis (dog, guinea pig)
** POlHL-0683517 0026 Cardiovascular disease -
Lipoproteins (human, guinea pig)
** POlHL-08974-14 0024 Natural and experimental
atherosclerosis - Atherosclerosis, sterol and lipoprotein
metabolism in nonhuman primates
ROlHL-09610-14 Control of cholesterol metabolism-Bile
acid transport
ROlHL-1239913 Specific fatty acids and cholesterol
metabolism (gerbils. rats)
** P01HL13262-07 0016 Arterial wall in atherosclerosis -
Lipids in elastin preparations from atherosclerotic plaques
(human, animals)
R01HL13405-09 Regulation of lipid metabolism in the
lung (rats)
P50HL-14236-05 0005 Prevention of premature
arteriosclerosis - Genetically hypertipidemic and
hypolipidemic rats
ROlHL-15793-06 Molecular aspects of erythrocyte
membrane resealing (human)
ROlHL-15799-04 Effect of anesthetics on myocardial
function (cats)
** R01HL1610105 Proteinlipid interaction (bacteria,
models)
POlHL-1613705 0001 Alveolar biology - Chemical
characterization of surfactant system-Lipid and lipid
protein fractions
ROlHL-16421-08 Determinants of RBC deformability and
capillary flow (human, mice)
** ROlHL-1651204 Lipoprotein metabolism and hormonal
regulation (chickens)
ROlHL-16725-03 Physiological regulation of pulmonary
surfactant (dogs, rats)
P60HL-1726904 0014 National heart and blood vessel
research and demonstration center - Physio-chemical nature
of lipid deposits in arterial wall (human)
** ROlHL-17567-03 Lipoprotein-cytolytic toxin interaction
(Staphylococcus aureus, mammals, human)
R01HL1800402 Transport through arterial wall-
Biophysical aspects (rabbits)
** ROlHL-18157-04 Subcellular events in atherosclerosis
(human, rabbits, calves)
** ROlHL-18181-04 Surfactant metabolism-Alveolar cells and
lung disease (mice, rabbits)
R01HL18473-04 Genesis of atherosclerotic lesions
(human, mules)
** POlHL-18577-03 0005 Lipoproteins-Celi surface
interactions - Chemical synthesis of apolipoproteins and
apoliprotein fragments
P50HL19185-02 0002 Pulmonary SCOR-Neonatal
respiratory distress syndromes • Biochemistry,
ultrastructure-Pulmonary surface active material (human,
animal)
ROlHL-19676-02 Physico-chemical interactions in
pulmonary surfactant
ROlHL-19982-02 Blood coagulation-Protein-metal ion-lipid
interactions
** ROlHL-20317-02 Procoagulant lipoproteins-Biochemistry
and bioactivity (goats, rabbits)
(contd)
•Excludes routine methodology OR covers only general projects which preclude
"Oriented significantly to above subject.
indexing at the specific level.
M Grant has subprojeds describing specific research aspects.
See Appendix for investigator's name and grant number.
ALP
ROlHL-20924-02 Atherosclerosis and arterial cell functions
(human, rabbits)
POlHL-20948-02 0002 Molecular basis of cholesterol
metabolism - LDL pathway in cell lines with informative
properties other than fibroblasts
" POlHL-2094802 0003 Molecular basis of cholesterol
metabolism ■ LDL pathway in vivo (human, rats, guinea
pigs)
" POlHL-20993-02 0007 Population dynamics of arterial
cells in atherogenesis - Interaction of lipoproteins in
hypercholesteremia (human, swine)
R23HL-21559'01 Oxygen supply and blood flow through
aortic vasa vasorum (dogs)
RGlHL-22029-02 Bronchopulmonary resistance to bacterial
infection (mice)
ROlHL-22053'02 The disordered lipid metabolism of
diabetes mellltus (chickens, mammals, human)
ROlHL-22174-01 Assembly of membranes in heart and
yeast mitochondria
M POlHL-22619-01 Cellular mechanisms of heart failure
** POlHL-2261901 0011 Cellular mechanisms of heart
failure - Reaction of lipoproteins and apolipoproteins with
lipoprotein lipase (cattle)
M POIHL'2263301 Cellular and molecular biology of
lipoprotein metabolism
** POlHL'22633-01 0001 Cellular and molecular biology of
lipoprotein metabolism - Secretion of lipoproteins by the
perfused liver (rats, rabbits)
** POlHL-22633-01 0004 Cellular and molecular biology of
lipoprotein metabolism - Lipid-lipid and lipidprotein
interactions in serum lipoproteins (human, rats)
•* POlHL-22633-01 9002 Cellular and molecular biology of
lipoprotein metabolism - Lipoprotein laboratory core
NOlHV-22917-11 Lipid research clinic (human)
ALPHA LIPOPROTEINS
SEE LIPOPROTEINS BLOOD, HDL
BETA LIPOPROTEINS
SEE LIPOPROTEINS BLOOD, LDL
UPOPROTEINS BLOOD
** N01HI-32926-10 Analysis of lipoproteins (animals)
ROlHL-02033-23 Regulation of cholesterol esters in blood
and tissues (rat, cattle, human)
R01HL02942-22 Biochemistry of cardiovascular connective
tissue (human, cattle, primates)
" ROlHL-02965-22 Metabolism of plasma lipoproteins (rats,
chickens, human)
ROlHL-03299-21 Oietaiv effects on cholesterol metabolism
(rats, rabbits)
ROlHL-0373418 Metabolism of arterial tissue in
atherosclerosis (rabbits)
** R01HL06221-17 Composition and structure of plasma
lipoproteins (human, turkeys, baboons)
ROlHL'06222-18 Clinical and laboratory studies in lipid
metabolism (human, mammals, non-human)
** P01HL-06285-I8 0203 Cardiovascular-respiratory
physiology and biochemistry - Pathways of lipid transport
in the blood (animals)
POlHL-06285-18 0207 Cardiovascular-respiratory
physiology and biochemistry - Feedback control of
cholesterol synthesis in non-hepatic tissues (animals)
POlHL-06835-17 0062 Cardiovascular disease ■ Role of
collagen in atherosclerosis (dogs, pigeons)
ROlHL-08506-15 Lipemia-carbohydrate and glyceride
metabolism (human, rats)
ROlHL-08634-15 Enzymic cholesterol synthesis (human,
rats, protozoa, yeast)
POlHL-09011-15 0005 A research and resource program
in blood - Characterization of hepatitis-B antigen and the
cause of serum hepatitis (human)
ROlHL-09739-13
ROlHL-10642-18
macaca)
ROlHL-10940-13
ROlHL-11822-10
Biophysical studies of proteins (human)
Plasma cholesterol metabolism (human.
Lipid transport (rabbits, cattle, chickens)
Biophysical studies of macromolecular
interactions (microorganism, human)
ROlHL-1 1901-12 0001 Effects of metabolic surgery on
the hyperlipidemias - Partial ileal bypass (human)
ROlHL-1 1901-12 0004 Effects of metabolic surgery on
the hyperlipidemias - Ileal bypass -Cholesterol dynamics
studies (rats, rabbits, dogs)
ROlHL-11901-12 0019 Effects of metabolic surgery on
the hyperlipidemias - Cholesterol, bileacids, lipoproteins in
obese humans
ROlHL-12085-10 Lipoprotein-carbohydrate metabolism
(human, rats)
POIHL 12373-10 0006 Cardiopulmonary physiology and
pathophysiology - Fatty acid metabolism -Regulation,
implications (human, mammals, birds)
ROlHL-12745-10 Enzymes and inhibitors of cholesterol
biosynthesis (rats, human, swine)
ROlHL-1286909 Arterial metabolism, diabetes and
atherogenesis (rats, rabbits)
P01HL13262-07 Arterial wall in atherosclerosis
POlHL-13262-07 0011 Arterial wall in atherosclerosis -
Role of hypertension in atherosclerosis (human, monkey,
dog)
ROIHL- 13302-09 Uptake and metabolism of lipids by the
liver (rats)
ROIHL- 13626-06 Lipoprotein lipase and lipoprotein
removal (human, rats, bacteria)
326
ROlHL-13722-08 Acid and alkaline lipases in aortas (rats.
rabbits, human)
P50HL-14141-05 0008 SCOR for atherosclerosis in
childhood - Core laboratory
P50HL-14164-07 A/S SCOR -Comparative and experimental
atherosclerosis
P50HL-14164-07 0029 A/S SCOR -Comparative and
experimental atherosclerosis - Development of pigeon
substrains
P50HL-14164 07 0030 A/S SCOR -Comparative and
experimental atherosclerosis - Morphology, angiochemistiy -
Diet induced lesions in African green monkey
P50HL-1416407 0033 A/S SCOR -Comparative and
experimental atherosclerosis - Comparative studies of
lipoprotein distribution and metabolism (monkeys)
P50HL-141 64-07 0034 A/S SCOR-Comparative and
experimental atherosclerosis - Core lipid analytic laboratory
P50HL-14 164-07 :'^35 A/S SCOR-Comparative and
experimental atherosclerosis - Lipid metabolism-Interaction
with arterial metabolism (monkey, pigeon)
P50HL-141 64-07 0036 A/S SCOR-Comparative and
experimental atherosclerosis - Connective tissue
metabolism-Interaction with arterial metabolism (monkeys)
P50HL-14164-07 0041 A/S SCOR-Comparative and
experimental atherosclerosis - Nonhuman primate pediatric
atherosclerosis risk factor
P50HL-14197-07 Support for center of research on
arteriosclerosis
P50HL14197-07 0005 Support for center of research on
arteriosclerosis - Lipoprotein biosynthesis and degradation
in vivo and In vitro (human, animal)
P50HL-14197-07 0006 Support for center of research on
arteriosclerosis - Diets and drugs affecting lipid
metabolism (human)
P50HL-14197-07 0007 Support for center of research on
arteriosclerosis - Metabolic defects in familial
hyperlipoproteinemias (human)
P50HL-14197-07 0008 Support for center of research on
arteriosclerosis - Core facllity-Llpoproteln preparation.
Immunochemistry
P50HL-14230-07 0092 A/S SCOR-Liplds, atherosclerosis
and thrombosis - Tissue llpids-Cell culture studies
(human)
P50HL-14230-07 9001 A/S SCOR-Liplds, atherosclerosis
and thrombosis - Core lipid laboratory
P50HL-1423e-05 0004 Prevention of premature
arteriosclerosis - Plasma lipoproteins (human, rats)
P50HL- 142 36-05 0008 Prevention of premature
arteriosclerosis - Lipoproteins of cell membranes (human)
P50HL-14237-07 Support for arteriosclerosis center
P50HL-14237-07 0001 Support for arteriosclerosis center
- Role of apolipoproteins in lipoprotein catabolism (human,
rats)
P50HL-14237-07 0002 Support for arteriosclerosis center
- Interactions of lipoprotein particles with vascular surface
(human, rat)
P50HL14237-07 0003 Support for arteriosclerosis center
- Structure of lipoproteins and apolipoproteins (human,
rabbits)
P50HL-14237-07 0004 Support for arteriosclerosis center
- Synthesis, secretion of normal, abnormal plasma
lipoproteins (rodents, monkeys)
P50HL-14237-07 0007 Support for arteriosclerosis center
- Core laboratories
ROlHL-143 13-07 Apoproteins of triglyceride rich
lipoproteins (human, squirrel monkeys, rats)
ROlHL-14378-07 Lipemias and reconstructive cardiac
surgery (human)
ROlHL-14781-08 Lipid deposition in mammalian cells
(mice)
ROlHL-14990-07 Lipid transport In avian species
(chickens)
P50HL-15062-07 Study of lipoproteins, artery wall, and
atherosclerosis
P50HL-15062-07 0001 Study of lipoproteins, artery wall,
and atherosclerosis - Structure and molecular interactions
of serum lipoproteins (human, monkey)
P50HL- 15062-07 0007 Study of lipoproteins, artery wall,
and atherosclerosis - Physical chemistry of lipid-protein
interaction (human)
P50HL-15062-07 0009
and atherosclerosis
(Rhesus monkeys)
P50HL-15062-07 0012
and atherosclerosis
smooth muscle cell
P50HL-15062-07 0013
and atherosclerosis -
(human, monkeys)
P50HL-15062-07 0019
and atherosclerosis -
Study of lipoproteins, artery wall.
■ Plasma lipoprotein biosynthesis
Study of lipoproteins, artery wall.
- Lipoprotein stimulation of arterial
proliferation (mammals)
Study of lipoproteins, artery wall.
Radioimmunoassay of apolipoproteins
Study of lipoproteins, artery wall.
Factors regulating lipoprotein-smooth
muscle cell interaction (monkey)
P50HL-15062-07 0021 Study of lipoproteins, artery wall,
and atherosclerosis - Core laboratories
P50HL-15I03-07 0013 A/S SCOR-Early natural history of
arteriosclerosis - Experimental models of atherosclerosis
(monkeys)
P50HL-15103-07 0014 A/S SCOR-Early natural history of
arteriosclerosis - Biochemistry of atherosclerotic lesions
(monkeys, human, cattle)
ROlHL-15263-06 Lecithin-Cholesterol acetyltransferase
(human, rabbits)
'Excludes routine methodokigy OR cavers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subiect.
LIP
R01HL-15308-07 Assays for peptides of lipoproteins
(human)
ROlHL-15427-06 Secretion of plasma lipoproteins (rats)
ROlHL-15478-05 Lipid flux and collagen synthesis In
atherosclerosis (rabbits)
ROlHL-15797-05 Lipid metabolism and atherosclerosis In
primates (monkeys, human, squirrels)
ROlHL-15895-05 In vitro study of lipoproteins in vascular
disease (human, animals)
ROIHL- 15930-06 Hormonal control of lipid and lipoprotein
synthesis (rats)
R01HL15949-05 Lipoprotein metabolism In relation to
atherosclerosis (human, baboons)
ROlHL-16294-04 Effectors of cholesterol synthesis (rats)
R01HL-ieS87-04 Cholesterol binding saponins and
atherosclerosis (monkeys)
ROlHL-16588-05 Collagen synthesis in atherosclerosis
(dogs. rats, rabbits, human)
ROlHL-16774-04 Genetic epidemiology of hyperlipemia
(Honolulu)
R01HLie807-02 Lipid structure of normal and
hyperlipoproteins (human)
P60HL- 17269-04 0001 National heart and blood vessel
research and demonstration center - Atherosclerosis-
Arterial pathology and plasma lipids (human)
P60HL- 17269-04 0011 National heart and blood vessel
research and demonstration center - Lipoprotein structure
laboratory (human)
P60HL- 17269-04 0013 National heart and blood vessel
research and demonstration center ■ Peptide synthesis
laboratory (human)
P60HL- 17269-04 0014 National heart and blood vessel
research and demonstration center - Physio-chemical nature
of lipid deposits in arterial wall (human)
P60HL-17269-04 0015 National heart and blood vessel
research and demonstration center - Lipoprotein
metabolism laboratory (human)
P60HL- 17269-04 0045 National heart and blood vessel
research and demonstration center - Regulation of
lipogenesis in hyperlipoproteinemia (human, tissue culture)
P60HL- 17269-04 0046 National heart and blood vessel
research and demonstration center - Nuclear magnetic
resonance laboratory
P60HL-17269-04 0048 National heart and blood vessel
research and demonstration center - Atherosclerosis -
Lipoproteins and the arterial wall (human)
ROlHL-17369-04 Arterial bypass surgery-Structure and
metabolism (monkeys)
ROlHL-17371-05 Regualtion of cholesteryl ester levels In
the aorta (swine)
ROlHL-17463-03 Composition and structure of plasma
lipoproteins (human, rabbits)
ROlHL-17567-03 Lipoprotein-cytolytic toxin interaction
(Staphylococcus aureus, mammals, human)
R01HL-17S97-05 Role of plasma lipoproteins in
atherosclerosis (swine, human)
ROlHL-17818-05 Metabolism of cholesterol and cholesterol
in man (also rats, monkeys)
ROlHL-17898-03 Cell membranes and plasma lipoproteins
(human, swine)
ROlHL-18152-03 Vascular injury and atherosclerosis
(mice, coxsackievirus)
POlHL-18574-03 Lipoprotein methodology and biomedical
applications
POIHL-18574-03 0001 Lipoprotein methodology and
biomedical applications - Ultracentrifugal and
electrophoretic lipoprotein methodology-Applications
POlHL-18574-03 0004 Lipoprotein methodology and
biomedical applications - Fine structure and metabolism of
lipoproteins-EM studies (guinea pigs)
POlHL-18574-03 0005 Lipoprotein methodology and
biomedical applications - Structure and function of
lipoproteins
POlHL-18574-03 0006 Lipoprotein methodology and
biomedical applications - Lipoprotein transformation.
lipolytic enzymes, diet and lipid lowering agents
POlHL-18577-03 Lipoproteins -Cell surface interactions
POlHL-18577-03 0003 Lipoproteins-Cell surface
interactions - Mechanism of lipid exchange in lipoproteins
and cell membranes
P0IHL-18577-C3 0004 Lipoproteins-Cell surface
interactions - Analysis and chemical modification of
proteins in lipid transport (human, dogs)
POlHL-18577-03 0008 Lipoproteins-Cell surface
interactions - Core laboratory 1
POlHL-18577-03 0011 Lipoproteins-Cell surface
interactions - Core laboratory 4
ROlHL-18623-12 Physical chemistry of biologically active
lipids (bacteria, plant, cattle, human)
P01HL18645-03 0001 Biology of the artery wall and
atherosclerosis - Primate arterial smooth muscle and
atherosclerosis
POlHL-18645-03 0004 Biology of the artery wall and
atherosclerosis - Human arterial smooth muscle cell and
lipoprotein interaction
ROlHL-18692-03 Glycosaminoglycans and lipoproteins of
human plasma
POlHL-18827-02 0005 Platelet vessel wall interactions in
thrombogenesis - Platelet vessel wall interactions in
thrombogenesis (human)
ROlHL-1888703 Hypolipidemic drugs-Effects on FFA-
albumin association (human, cattle)
(contd)
M Grant has subprojects describing specific research aspects.
See Appendix for Investigator's name and grant number.
JP
•• R01H119001 03 Wh«roscl»rosis in bleedei and drug
traitad subiacts (pigs)
■* ROIHL 1906303 Cholesteiol and lipoprotein metabolism
(rat hepatocytes)
•* PO1HL1924202 0002 Study ol vascular smooth muscle
Vascular smooth muscle response to serum lipoproteins
(rats)
PSOHl 19362 02 0001 A/S SCOR Atherosclerosis in
nonhuman primates Etlects ol inlant nutrition on
atherosclerosis (baboons)
P50HI 1936202 0003 A/S SCOR Atherosclerosis m
nonhuman primates Heritability of characters related to
atherosclerosis (baboons)
P50HL 19362 02 OOOi A/S SCOR -Athecosclerosis in
nonhuman primates Hybridization to produce primate
model ol atherosclerosis (baboon. Rhesus)
P50HL 1936202 0006 A/S SCOR Atherosclerosis in
nonhuman primates Ettects ol cigarette smoking on
atherosclerosis (baboon)
P50HL 1936202 0013 A/S SCOR -Atherosclerosis in
nonhuman primates ■ Core laboratory- Lipid biochemistry
(baboons)
** ROIHL- 1945903 Dynamics ot atherogenesis and
lipoprotein formation (human, rabbit)
ROlHL-2018901 Effects of renin on atherogenesis
(rabbits)
ROlHL-20197-02 Maintenance and repair of vascular
endothelium (human, animals)
ROlHL-20350-02 Crystal structure of lipids-Cholesterol
ROlHL-20488-03 Cholesterol metabolism in diabetic man
ROIHL 2064501 Etiology of myocardial intaction (human)
** ROlHL-20882 02 Interactions of plasma lipoproteins viith
erythrocytes (Rhesus, human)
** ROlHL-20954-02 Hyperlipoproteinemia (rats, human)
ROlHL-21260-02 RisK factor relationships of
atherosclerosis (monkeys)
R01HL-21303-D2 Collagen synthesis by cultured human
vascular cells
*• ROlHL-21429-02 Transport of LDL in arterial wall (human,
mammals)
** ROlHL-2143802 Structure and permeability of arterial
endothelium (pigs)
** ROlHL-21460-02 Lipoproteins, hemostasis and
atherosclerosis (human, rabbits)
•* ROlHL-21592-01 Lipoproteins and coagulation factors in
atherosclerosis (pigeons)
ROlHL-21764-01 Ultramicroanalysis of prostaglandins and
related compounds (rats)
•* ROlHL-22052-01 Organization of free cholesterol in serum
lipoproteins (human, dogs)
** ROlHL-22456-01 Lipoproteins in bioregulation of the
immune response (mice, human)
** ROlHL-22570-01 Interactions of sterols in biological
systems (human)
** ROlHL-22607-01 Role of apolipoprotein E in lipoprotein
metabolism (human)
** ROlHL-22627-01 An inhibitor of platelet adhesion to
artificial organs (human)
** POlHL-2263301 0002 Cellular and molecular biology of
lipoprotein metabolism - Sterol metabolism in tissue
culture cells
** POlHL-22633-01 0003 Cellular and molecular biology ot
lipoprotein metabolism - Sterol metabolism in platelets and
megakaryocytes (human, rabbits, guinea pigs)
** POlHL-22633-01 0004 Cellular and molecular biology of
lipoprotein metabolism - Lipid-lipid and lipid-protein
interactions in serum lipoproteins (human, rats)
ROlHL-22967-01 Structure and function of heparin
releasable lipases (swine, human)
** ROlHL-22983-01 Studies on the catabolism of plasma
lipoproteins (rats)
** R01HL-23945-05 Pathologic effects on cells of modified
lipoproteins (rats, human)
♦* NOlHV-53015-09 Establishment of a lipid research clinic
(human)
NOlHV-62955-04 Data collection in clinical pathology and
morbid anatomy (men)
** NOlHV-72917-00 Plasma lipoproteins in identical twins
UPOPROTEINS BLOOD, DYSIIPOPROTEINEMIAS
" POlHL-06835-17 0064 Cardiovascular disease - Studies
in atherosclerosis (human, animals)
** POlHL-08974-14 0024 Natural and experimental
atherosclerosis - Atherosclerosis, sterol and lipoprotein
metabolism in nonhuman primates
P50HL-14237-07 0003 Support for arteriosclerosis center
- Structure of lipoproteins and apolipoprotcins (human,
rabbits)
P50HL-14237-07 0005 Support for arteriosclerosis center
- Genetic determinants of apolipoprotein variability in
lipoproteins (human)
** ROlHL-15308-07 Assays for peptides of lipoproteins
(human)
M POlHL-18577-03 Lipoproteins-Cell surface interactions
P01HL1857703 0001 Lipoproteins-Cell surface
interactions - Structural studies of serum lipoproteins in
man and dogs
** ROlHL-2212102 Dyslipoproteinemia in diabetes and
vascular disease (human)
NOlHV-5302904 Nonhuman primate models of
atherosclerosis
NOlHV-53030-05 Nonhuman primate models of
atherosclerosis and hypertension
3-27
NOIHV 53031 04 Nonhuman primate models of
atherosclerosis and hypertension
NOIHV 62905 02 Nonhuman primate models ol
arteriosclerosis
NOIHV 7297802 Development ot models of hypertension
NOIHV 7298002 Development of models of hypertension
UPOPROTEINS BLOOD, HDL
SEE ALSO METABOLIC DISORDERS INBORN,
HYPOLIPOPROIEINEMIAS FAMILIAL, TANGIER
DISEASE
POIHL 031 74 23 0009 Mechanisms ot acute vascular
reaction to in|uiy Mast cell lipid interaction (human, rats)
R01HL05062 18 Lipid metabolism in cultured cells
(human, rats, rabbits)
P01HL06285 18 0203 Cardiovascular-respiratory
physiology and biochemistry Pathways of lipid transport
in the blood (animals)
POIHL 06285-18 0204 Cardiovascular respiratory
physiology and biochemistry Lipoprotein lipase and
triglyceride transport in chylomicrons (guinea pig. rat)
P01HL06285-18 0205 Cardiovascular respiratory
physiology and biochemistry • Assimilation of cholesterol in
chylomicrons and VLDL (rabbits)
ROlHL-0648115 Lipid metabolism (human, rats)
POlHL-06835-17 0064 Cardiovascular disease Studies
in atherosclerosis (human, animals)
** P01HL08974 14 0024 Natural and experimental
atherosclerosis Atherosclerosis, sterol and lipoprotein
metabolism in nonhuman primates
** ROlHL-10642-18 Plasma cholesterol metabolism (human,
macaca)
R01HL12085 10 Lipoproteincarbohydrate metabolism
(human, rats)
POlHL-13262-07 0011 Arterial wall in atherosclerosis -
Role of hypertension in atherosclerosis (human, monkey,
dog)
POlHL-1326207 0025 Arterial wall in atherosclerosis -
Phospholipid and cholesterol esters
P50HL-14164-07 0029 A/S SCOR -Comparative and
experimental atherosclerosis - Development of pigeon
substrains
P50HL-14164-07 0033 A/S SCOR -Comparative and
experimental atherosclerosis - Comparative studies of
lipoprotein distribution and metabolism (monkeys)
P50HL-14164-07 0035 A/S SCOR -Comparative and
experimental atherosclerosis - Lipid metabolism-Interaction
with arterial metabolism (monkey, pigeon)
P50HL-14164-07 0037 A/S SCOR -Comparative and
experimental atherosclerosis - Genetic control of plasma
cholesterol -Interaction of dietary fatty acid (monkey)
P50HL-14197-07 0005 Support for center of research on
arteriosclerosis - Lipoprotein biosynthesis and degradation
in vivo and in vitro (human, animal) v
P50HL-14237-07 0001 Support for arteriosclerosis center
- Role of apolipoproteins in lipoprotein catabolism (human,
rats) ,
P50HL-14237-07 0002 Support for arteriosclerosis center
- Interactions of lipoprotein particles with vascular surface
(human, rat)
P50HL-14237-07 0003 Support for arteriosclerosis center
- Structure of lipoproteins and apolipoproteins (human,
rabbits)
P50HL-14237-07 0004 Support for arteriosclerosis center
- Synthesis, secretion of normal, abnormal plasma
lipoproteins (rodents, monkeys)
P50HL-14237-07 0005 Support for arteriosclerosis center
- Genetic determinants of apolipoprotein variability in
lipoproteins (human)
ROlHL-143 13-07 Apoproteins of triglyceride rich
lipoproteins (human, squirrel monkeys, rats)
P50HL-15062-07 0001 Study of lipoproteins, artery wall,
and atherosclerosis - Structure and molecular interactions
of serum lipoproteins (human, monkey)
P50HL- 15062-07 0009 Study of lipoproteins, artery wall,
and atherosclerosis - Plasma lipoprotein biosynthesis
(Rhesus monkeys)
P50HL-15062-07 0013 Study of lipoproteins, artery wall,
and atherosclerosis - Radioimmunoassay of apolipoproteins
(human, monkeys)
P50HL- 15062-07 0019 Study of lipoproteins, artery wall,
and atherosclerosis - Factors regulating lipoprotein-smooth
muscle cell interaction (monkey)
P50HL-15103-07 0014 A/S SCOR -Early natural history of
arteriosclerosis - Biochemistry of atherosclerotic lesions
(monkeys, human, cattle)
** ROlHL-15308-07 Assays for peptides of lipoproteins
(human)
** ROlHL-15427-06 Secretion of plasma lipoproteins (rats)
** ROlHL-16059-06 Structure and function of serum
lipoproteins (cattle, human)
ROlHL-16364-04 Regulation of lipid biosynthesis and
transport (rats, swine, Xenopus)
ROlHL-165 12-04 Lipoprotein metabolism and hormonal
regulation (chickens)
*♦ P60HL- 172 69-04 0009 National heart and blood vessel
research and demonstration center - Physical methods
laboratory (high density lipoproteins)
P60HL-1 7269-04 0015 National heart and blood vessel
research and demonstration center - Lipoprotein
metabolism laboratory (human)
** R01HL17463-03 Composition and structure of plasma
lipoproteins (human, rabbits)
UP
ROIHI 1/898 03 Cell membrane! and pla»ma lipopiolaini
(human, swine)
POIHI 18')/4 03 0001 Lipoprotein methodology and
biomedical applications Ullracenliifugal and
electrophoietic lipoprotein methodology Applications
POIHI 185/4 03 0004 Lipoprotein methodology and
biomed cal applications Fine structure and metabolism ol
lipoproteins EM studies (guinea pigs)
POIHL 185/4 03 0005 Lipoprotein methodology and
biomedical applications Structure and function of
lipoproteins
POIHL 18574 03 0006 Lipoprotein methodology and
biomeical applications Lipoprotein transformation,
lipolytic enzymes, diet and lipid lowering agents
' POIHL 18577 03 0001 Lipoproteins Cell surface
interactions Structural studies of serum lipoproteins in
man and dogs
POIHL 18577 03 0004 Lipoproteins Cell surface
interactions Analysis and chemical modification of
proteins in lipid transport (human, dogs)
ROIHL 18692 03 Glycosaminoglycans and lipoproteins of
human plasma
* ROIHL 19168-03 Biosynthesis of plasma lipoprotein (rats.
rabbits)
POIHL 19242 02 0002 Study of vascular smooth muscle
Vascular smooth muscle response to serum lipoproteins
(rats)
* ROIHL 19250 03 Mechanism of plasma cholesterol
esterification (human)
ROIHL 19459-03 Dynamics of atherogenesis and
lipoprutein formation (human, rabbit)
•* ROIHL 20061 02 Serum lipoproteins and cell cholesterol
metabolism (rats, human)
ROIHL 20418-03 Serum cholesterol binding reserve in
diabetes (human)
ROlHL-20645-01 Etiology of myocardial infaction (human)
•* ROlHL-20954-02 Hyperlipoproteinemia (rats, human)
R01HL21303-02 Collagen synthesis by cultured human
vascular cells
ROIHL 22052-01 Organization of free cholesterol in serum
lipoproteins (human, dogs)
ROlHL-22053-02 The disordered lipid metabolism of
diabetes mellitus (chickens, mammals, human)
ROIHL 22570-01 Interactions of sterols in biological
systems (human)
ROlHL-22618-01 Role of apolipoproteins in
hypertriglyceridemia (human)
** POlHL-22619-01 0012 Cellular mechanisms of heart
failure Apolipoproteins in hypertriglyceridemia (human)
POlHL-22633-01 0001 Cellular and molecular biology of
lipoprotein metabolism • Secretion of lipoproteins by the
perfused liver (rats, rabbits)
POlHL-22633-01 0003 Cellular and molecular biology of
lipoprotein metabolism - Sterol metabolism in platelets and
megakaryocytes (human, rabbits, guinea pigs)
** POlHL-22633-01 0004 Cellular and molecular biology of
lipoprotein metabolism - Lipid-lipid and lipid-protein
inteiactions in serum lipoproteins (human, rats)
** ROlHL-22682-01 Structure and function of high density
lipoprotein (human, rat)
** ROIHL 22812-01 Regulation of hepatic production of HDL
(rats)
ROlHL-23945-06 Pathologic effects on cells of modified
lipoproteins (rats, human)
UPOPROTEINS BLOOD, HYPERUPOPROTEINEMIA
SEE ALSO METABOLIC DISORDERS INBORN,
HYPERLIPOPROTEINEMIAS FAMILIAL
** ROlHL-02965-22 Metabolism of plasma lipoproteins (rats,
chickens, human)
R0;HL-0622117 Composition and structure of plasma
lipoproteins (human, turkeys, baboons)
POlHL-06835-17 0014 Cardiovascular disease - Dietary
induction of severe atherosclerosis and its prevention
(dogs)
POlHL-06835-17 0021 Cardiovascular disease - Animal
study in atherosclerosis (dog, guinea pig)
ROlHL-08506-15 Lipemia-carbohydrate and glyceride
metabolism (human, rats)
ROlHL-09914-13 The myocardium in diabetes mellitus
(dogs, monkeys)
" RniHL11901-12 0013 Effects of metabolic surgery on
the hyperlipidemias - Human cholesterol and bile acids
dynamics -Ileal bypass
POlHL-12373-10 0006 Cardiopulmonary physiology and
pathophysiology Fatty acid metabolism -Regulation,
implications (human, mammals, birds)
** ROlHL-12740-10 Hypocholesterolemic agents-
Stereochemistry (rats)
ROlHL-12869-09 Arterial metabolism, diabetes and
atherogenesis (rats, rabbits)
ROlHL-1362606 Lipoprotein lipase and lipoprotein
removal (human, rats, bacteria)
RClHL-13654-08 Antilipemic regimes in peripheral
arteriosclerosis (human)
P50HL-14138-05 0009 Center for research on
atherosclerosis - Core angiographic-diagnostic laboratory
(human, dogs, birds)
P50HL-14164-07 0030 A/S SCOR -Comparative and
experimental atherosclerosis - Morphology, angiochemistry-
Diet induced lesions in African green monkey
(contd)
•Excludes routine methodotogy OR covers only general projects which preclude
••Oriented significanthr to above subject.
ndexing at the specific level.
M Grant has subprojccts describing specific research aspects.
See Appendix for investigator's name and grant number.
LIP
P50HL14236-05 0002 Prevention of premature
arteriosclerosis - Myocardial blood flow in patients with
coronary artherosclerosis
P50HLU236-05 0004 Prevention of premature
arteriosclerosis - Plasma lipoproteins (human, rats)
** P50HL-14236-05 0007 Prevention of premature
arteriosclerosis - Exercise stress testing
hyperlipoproteinemia (human)
P50HL-14236-05 0008 Prevention of premature
arteriosclerosis - Lipoproteins of cell membranes (human)
M P50HL-14237-07 Support for arteriosclerosis center
P50HL-14237-07 0001 Support for arteriosclerosis center
- Role of apolipoproteins in lipoprotein catabolism (human,
rats)
P50HL-14237-07 0003 Support for arteriosclerosis center
- Structure of lipoproteins and apolipoproteins (human,
rabbits)
P50HL-14237-07 0004 Support for arteriosclerosis center
• Synthesis, secretion of normal, abnormal plasma
lipoproteins (rodents, monkeys)
** P50HL-1423707 0005 Support for arteriosclerosis center
- Genetic determinants of apolipoprotein variability in
lipoproteins (human)
" P50HL-1 506207 0001 Study of lipoproteins, artery wall,
and atherosclerosis Structure and molecular interactions
of serum lipoproteins (human, monkey)
P50HL-15062-O7 0009 Study of lipoproteins, artery wall,
and atherosclerosis - Plasma lipoprotein biosynthesis
(Rhesus monkeys)
P50HL1506207 0013 Study of lipoproteins, artery wall,
and atherosclerosis - Radioimmunoassay of apolipoproteins
(human, monkeys)
M P50HL15103-07 A/S SCOR-Early natural history of
arteriosclerosis
P50HL-15103-07 0001 A/S SCOR-Early natural history of
arteriosclerosis - Clinical research-Bogalusa heart study
(children)
" P50HL15103-07 0013 A/S SCOR-Early natural history of
arteriosclerosis - Experimental models of atherosclerosis
(monkeys)
•* ROlHL-15263-06 Lecithin-Cholesterol acetyltransferase
(human, rabbits)
M POIHL 15265-05 Program on surgical control of the
hyperlipidemias
** POlHL-15265-05 0003 Program on surgical control of the
hyperlipidemias - Central lipid laboratory
** P01HL1526505 0004 Program on surgical control of the
hyperlipidemias - Coordinating center and central data
processing facility
" POlHL-15265-05 0011 Program on surgical control of the
hyperlipidemias - Central electrocardiography laboratory
(human)
" P01HL15265-05 0012 Program on surgical control of the
hyperlipidemias ■ Central arteriography-Radiography
laboratory (human)
** POlHL-15265-05 0013 Program on surgical control of the
hyperlipidemias ■ Clinical center - Minnesota
** POlHL-15265-05 0014 Program on surgical control of the
hyperlipidemias - Arkansas clinical center
** ROlHL-15308-07 Assays for peptides of lipoproteins
(human)
ROlHL-1746303 Composition and structure of plasma
lipoproteins (human, rabbits)
P50HL183 18-03 0014 Pathogenesis and complications of
hypertension - Arterial metabolism and atherogenesis (rat
rabbit)
POlHL-18574-03 0006 Lipoprotein methodology and
biomedical applications - Lipoprotein transformation,
lipolytic enzymes, diet and lipid lowering agents
ROlHL-19084-03 Structure and function of serum
lipoproteins (human)
POlHL-19242-02 0002 Study of vascular smooth muscle -
Vascular smooth muscle response to serum lipoproteins
(rats)
ROlHL-20381-03 Long-term study of diabetic vascular
disease (human)
ROlHL-20391-03 Polydisperse LDL-Structure, metabolism
and function (human)
** ROlHL-2039703 VLDL-TG metabolism in diabetes mellitis
(human, rat)
ROlHL-20426-03 Myocardial function in diabetes mellitus
(dog, rat)
ROIHL-20954-02 Hyperlipoproteinemia (rats, human)
** ROlHL-21260-02 Risk factor relationships of
atherosclerosis (monkeys)
ROlHL-21303-02 Collagen synthesis by cultured human
vascular cells
ROlHL-21416-02 Atherosclerosis in new modles of
diabetes mellitus
ROlHL-22367-01 Estrogen receptors in very low density
lipoproteins (chicken livers)
*• R01HL-22618-01 Role of apolipoproteins in
hypertriglyceridemia (human)
M POlHL-22619-01 Cellular mechanisms of heart failure
" POlHL-22619-01 0011 Cellular mechanisms of heart
failure - Reaction of lipoproteins and apolipoproteins with
lipoprotein lipase (cattle)
** POlHL-226 19-01 0012 Cellular mechanisms of heart
failure - Apolipoproteins in hypertriglyceridemia (human)
ROlHL-22967-01 Structure and function of heparin
releasable lipases (swine, human)
** NOlHV-12156-10 Lipid research clinic
NOlHV-12157-14
NOlHV-12158-10
NOlHV-12159-09
N01HV12160-15
NOlHV-22913-09
NOlHV-22914-08
NOlHV-22915-11
NOIHV-22916-16
NOlHV-22917-11
NOlHV-22932-09
NOlHV-32931-09
center
NOlHV-53015-09
(human)
328
Lipid research
Establishment
Lipid research
Establishment
Lipid research
Establishment
Establishment
Establishment
Lipid research
Establishment
Establishment
clinic (human)
of a lipid research clinic
clinic
of a lipid research clinic
clinic
of a lipid research clinic
of lipid research clinic
of a lipid research clinic
clinic (human)
of a lipid research clinic
of a lipid research clinic
Establishment of a lipid research clinic
LIPOPROTEINS BLOOD, HYPOLIPOPROTEINEMIA
ROlHL-06221-17 Composition and structure of plasma
lipoproteins (human, turkeys, baboons)
P01HL18577-03 0001 Lipoproteins -Cell surface
interactions - Structural studies of serum lipoproteins in
man and dogs
ROlHL-20954-02 Hyperlipoproteinemia (rats, human)
ROlHL-21303-02 Collagen synthesis by cultured human
vascular cells
LIPOPROTEINS BLOOD, LDL
SEE ALSO METABOLIC DISORDERS INBORN,
HYPERLIPOPROTEINEMIAS FAMILIAL, TYPE II
SEE ALSO METABOLIC DISORDERS INBORN,
HYPERLIPOPROTEINEMIAS FAMILIAL, TYPE III
SEE ALSO METABOLIC DISORDERS INBORN,
HYPERLIPOPROTEINEMIAS FAMILIAL, TYPE V
SEE ALSO METABOLIC DISORDERS INBORN,
HYPOLIPOPROTEINEMIAS FAMILIAL,
ABETALIPOPROTEINEMIA
POlHL-031 74-23 0009 Mechanisms of acute vascular
reaction to injury - Mast cell lipid interaction (human, rats)
ROlHL-05062-18 Lipid metabolism in cultured cells
(human, rats, rabbits)
POlHL-06285-18 0203 Cardiovascular-respiratory
physiology and biochemistry - Pathways of lipid transport
in the blood (animals)
POlHL-06285-18 0204 Cardiovascular-respiratory
physiology and biochemistry - Lipoprotein lipase and
triglyceride transport in chylomicrons (guinea pig, rat)
POlHL-06285-18 0205 Cardiovascular-respiratory
physiology and biochemistry - Assimilation of cholesterol in
chylomicrons and VLDL (rabbits)
POlHL-06835-17 0064 Cardiovascular disease - Studies
in atherosclerosis (human, animals)
** ROlHL-09744-14 Experimental vascular sclerosis
(monkeys, rabbits)
R01HL1031613 Structural studies on low density serum
lipoproteins (human)
ROlHL-1 1901-12 0001 Effects of metabolic surgery on
the hypertipidemias - Partial ileal bypass (human)
ROlHL-1 1901-12 0013 Effects of metabolic surgery on
the hypertipidemias - Human cholesterol and bile acids
dynamics-Meal bypass
ROlHL-12085-10 Lipoprotein-carbohydrate metabolism
(human, rats)
P01HL1326207 0011 Arterial wall in atherosclerosis -
Role of hypertension in atherosclerosis (human, monkey,
dog)
POlHL-1326207 0025 Arterial wall in atherosclerosis -
Phospholipid and cholesterol esters
P50HL-1416407 0027 A/S SCOR-Comparative and
experimental atherosclerosis - Hyper- and
hyporesponsiveness to dietary cholesterol (squirrel monkey)
P50HL-14164-07 0029 A/S SCOR-Comparative and
experimental atherosclerosis - Development of pigeon
substrains
P50HL-14164-07 0031 A/S SCOR-Comparative and
experimental atherosclerosis - Changes in endothelial
permeability associated with atherosclerosis (pigeon)
P50HL-14164-07 0033 A/S SCOR-Comparative and
experimental atherosclerosis - Comparative studies of
lipoprotein distribution and metabolism (monkeys)
P50HL-141 64-07 0035 A/S SCOR-Comparative and
experimental atherosclerosis - Lipid metabolism-Interaction
with arterial metabolism (monkey, pigeon)
P50HL-14164-07 0037 A/S SCOR-Comparative and
experimental atherosclerosis - Genetic control of plasma
cholesterol-Interaction of dietary fatty acid (monkey)
P50HL-14197-07 0005 Support for center of research on
arteriosclerosis - Lipoprotein biosynthesis and degradation
in vivo and in vitro (human, animal)
P50HL-141 97-07 0007 Support for center of research on
arteriosclerosis - Metabolic defects in famihal
hyperlipoproteinemias (human)
P50HL-14230-07 0094 A/S SCOR-Lipids, atherosclerosis
and thrombosis ■ Studies of atherosclerosis and regression
(monkeys)
P50HL-14237-07 0002 Support for arteriosclerosis center
Interactions of lipoprotein particles with vascular surface
(human, rat)
P50HL-14237-07 0003 Support for arteriosclerosis center
- Structure of lipoproteins and apolipoproteins (human,
rabbits)
P50HL-14237-07 0004 Support for arteriosclerosis center
- Synthesis, secretion of normal, abnormal plasma
lipoproteins (rodents, monkeys)
LIP
P50HL-14237-07 0005 Support for arteriosclerosis center
- Genetic determinants of apolipoprotein variability in
lipoproteins (human)
P50HL14237-07 0006 Support for arteriosclerosis center
- Drug treatment of familial hyperbetalipoproteinemia
(human)
ROlHL-14313-07 Apoproteins of triglyceride rich
lipoproteins (human, squirrel monkeys, rats)
P50HL15062-07 0001 Study of lipoproteins, artery wall,
and atherosclerosis - Structure and molecular interactions
of serum lipoproteins (human, monkey)
P50HL1506207 0012 Study of lipoproteins, artery wall,
and atherosclerosis • Lipoprotein stimulation of arterial
smooth muscle cell proliferation (mammals)
P50HL-1506207 0013 Study of lipoproteins, artery wall,
and atherosclerosis - Radioimmunoassay of apolipoproteins
(human, monkeys)
P50HL 15062-07 0019 Study of lipoproteins, artery wall,
and atherosclerosis - Factors regulating lipoproteinsmooth
muscle cell interaction (monkey)
P50HL-15103-07 0014 A/S SCOR-Early natural history of
arteriosclerosis ■ Biochemistry of atherosclerotic lesions
(monkeys, human, cattle)
ROlHL-15308-07 Assays for peptides of lipoproteins
(human)
ROlHL-1589505 In vitro study of lipoproteins in vascular
disease (human, animals)
ROlHL-15949-05 Lipoprotein metabolism in relation to
atherosclerosis (human, baboons)
ROlHL-16364-04 Regulation of lipid biosynthesis and
transport (rats, swine, Xenopus)
** ROlHL-16419-03 Arterial uptake of lipoprotein-Kinetic
analysis (rabbits)
ROlHL-16512-04 Lipoprotein metabolism and hormonal
regulation (chickens)
P60HL-1 7269-04 0001 National heart and blood vessel
research and demonstration center • Atherosclerosis-
Arterial pathology and plasma lipids (human)
P60HL-1 7269-04 0011 National heart and blood vessel
research and demonstration center ■ Lipoprotein structure
laboratory (human)
P60HL-1 7269-04 0015 National heart and blood vessel
research and demonstration center - Lipoprotein
metabolism laboratory (human)
P60HL- 17269-04 0045 National heart and blood vessel
research and demonstration center - Regulation of
lipogenesis in hyperlipoproteinemia (human, tissue culture)
P60HL- 17269-04 0048 National heart and blood vessel
research and demonstration center - Atherosclerosis-
Lipoproteins and the arterial wall (human)
ROlHL-17898-03 Cell membranes and plasma lipoproteins
(human, swine)
ROlHL-18553-03 Membrane defects in familial
hypercholesteremia (human)
POlHL-18574-03 0004 Lipoprotein methodology and
biomedical applications - Fine structure and metabolism of
lipoproteins-EM studies (guinea pigs)
POlHL-18574-03 0005 Lipoprotein methodology and
biomedical applications - Structure and function of
lipoproteins
POlHL-18574-03 0006 Lipoprotein methodology and
biomedical applications - Lipoprotein transformation,
lipolytic enzymes, diet and lipid lowering agents
** POlHL-18577-03 0001 Lipoproteins-Cell surface
interactions - Structural studies of serum lipoproteins in
man and dogs
POlHL-18577-03 0004 Lipoproteins-Cell surface
interactions - Analysis and chemical modification of
proteins in lipid transport (human, dogs)
ROlHL-18692-03 Glycosaminoglycans and lipoproteins of
human plasma
ROlHL-18736-03 Protein transport through arterial tissue
(rabbits)
POlHL-18827-02 0005 Platelet vessel wall interactions in
thrombogenesis - Platelet vessel wall interactions in
thrombogenesis (human)
ROlHL-18878-03 Familial hypercholesteremia-Studies of
fibroblasts (human)
** ROlHL-19084-03 Structure and function of serum
lipoproteins (human)
R01HL19095-03 Laser spectroscopy of lipoproteins
(human)
ROlHL-19175-03 Pituitary modulation of micro-and macro-
vascular disease (human, rats)
POlHL-19242-02 0002 Study of vascular smooth muscle -
Vascular smooth muscle response to serum lipoproteins
(rats)
ROlHL-19250-03 Mechanism of plasma cholesterol
esterification (human)
ROlHL-19459-03 Dynamics of atherogenesis and
lipoprotein formation (human, rabbit)
ROlHL-20061-02 Serum lipoproteins and cell cholesterol
metabolism (rats, human)
** ROlHL-20391-03 Polydisperse LDL-Structure, metabolism
and function (human)
ROlHL-20645-01 Etiology of myocardial infaction (human)
** ROlHL-20712-02 Characterization of the B proteins of
serum lipoproteins (human)
ROlHL-20882-02 Interactions of plasma lipoproteins with
erythrocytes (Rhesus, human)
M POlHL-20948-02 Molecular basis of cholesterol
metabolism
•Excludes routine methodology OR covers only general projects which preclude indexing
'Oriented significantly to above subject
at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
(contd)
IP
• POIHL 20948 02 0001 Moleculsi basis ot cholesteiol
metabolism Biochemical end ulti.isltuctuial
chiracteruetion ot LOL in human libioblasts
• POIHL 20948 02 0002 Molecular basis ot cholesteiol
metabolism LDl pathway in cell lines with inloimative
properties othei than libioblasts
'• POIHI 20948 02 0003 Moleculai basis ot cholesterol
metabolism LDL p»lhw»y m vivo (human. lats. guinea
pigs)
•* POIHL 2094802 0004 Moleculai basis ot cholesterol
metabolism Genetic analysis ot the LDL pathway (human)
•• ROIHL 20954 02 Hypeilipopioteinemia (lals. human)
ROlHL-2130302 Collagen synthesis by cultuied human
vasculai cells
ROlHL-2205201 Oiganuation of tree cholesterol in seiuni
lipoproteins (human, dogs)
ROIHL 22053 02 The disoideied lipid metabolism of
diabetes mellitus (chickens, mammals, human)
ROIHL 22570 01 Interactions of sterols in biological
systems (human)
ROIHL 2262301 Polyamines cellular mediators of
atheiogenesis (human)
POlHL-2263301 0003 Cellulai and moleculai biology of
lipoprotein metabolism Sterol metabolism in platelets and
megaKaryocytes (human. labbits. guinea pigs)
LIPOPROTEINS BIOOD, VlDl
SEE ALSO METABOLIC DISORDERS INBORN.
HYPERLIPOPROTEINEMIAS FAMILIAL. TYPE 111
SEE ALSO METABOLIC DISORDERS INBORN,
HYPERLIPOPROTEINEMIAS FAMILIAL. TYPE IV
POlHL-03174-23 0009 Mechanisms of acute vasculai
reaction to injuiy - Mast cell lipid inteiaction (human. lals)
POlHL-0628518 0203 Cardiovascularrespiratoiy
physiology and biochemistiy Pathways ot lipid transport
in the blood (animals)
POlHL-06285-18 0204 Caidiovasculai-respiiatory
physiology and biochemistry Lipoprotein lipase and
tiiglyceiide tiansport in chylomicrons (guinea pig. rat)
•* POlHL-0628518 0205 Cardiovasculai-respiiatoiy
physiology and biochemistry • Assimilation of cholesterol in
chylomicrons and VLDL (rabbits)
ROlHL-08506-15 Lipemia-caibohydiate and glyceiidc
metabolism (human. lats)
R01HL0948913 Myocaidial lipid metabolism and
regulation (lats)
ROlHL-1064218 Plasma cholesterol metabolism (human,
macaca)
** R01HL10933-13 Fat metabolism and atherosclerosis
(rabbits, cattle, human, lats)
R01HL1182210 Biophysical studies of macromolecular
interactions (microorganism, human)
R01HL12085-10 Lipopiotein-caibohydiate metabolism
(human. lats)
P01HL1237310 0006 Caidiopulmonaiy physiology and
pathophysiology ■ Fatty acid metabolism-Regulation,
implications (human, mammals, birds)
P01HL1326207 0011 Arterial wall in atherosclerosis ■
Role of hypertension in atherosclerosis (human, monkey,
dog)
P50HL-14 164-07 0027 A/S SCOR -Comparative and
experimental atherosclerosis ■ Hypei- and
hyporesponsiveness to dietaiy cholesterol (squirrel monkey)
P50HL-14164-07 0029 A/S SCOR -Comparative and
experimental atherosclerosis - Development of pigeon
substrains
P50HL14I64-07 0033 A/S SCOR -Compaiative and
expeiimental atherosclerosis ■ Comparative studies of
lipoprotein distribution and metabolism (monkeys)
P50HL-14164-07 0035 A/S SCOR -Comparative and
experimental atherosclerosis - Lipid metabolism -Inteiaction
with arterial metabolism (monkey, pigeon)
P50HL-14164-07 0037 A/S SCOR -Comparative and
experimental atherosclerosis - Genetic control of plasma
cholesterol -Interaction ot dietary fatty acid (monkey)
P50HL14197-07 0005 Support for center of research on
arteiiosclerasis ■ Lipoprotein biosynthesis and degradation
in vivo and in vitio (human, animal)
P50HL-14197-07 0006 Support for center of research on
arteiiosclerosis Diets and drugs affecting lipid
metabolism (human)
P50HL-14197-07 0007 Support for center of research on
arteriosclerosis ■ Metabolic defects in familial
hyperlipoproteinemias (human)
P50HL-14237-07 0001 Support for arteriosclerosis center
■ Role of apolipoproteins in lipoprotein catabolism (human,
rats)
P50HL-1423707 0002 Support for arteriosclerosis center
- Interactions of lipoprotein particles with vascular surface
(human. lat)
P50HL-14237-07 0003 Support foi arteriosclerosis center
- Structure of lipoproteins and apolipoproteins (human,
labbits)
P50HL14237-07 0004 Support foi arteriosclerosis center
- Synthesis, secretion of normal, abnormal plasma
lipoproteins (rodents, monkeys)
** P50HL14237-07 0005 Support foi arteiiosclerosis center
• Genetic determinants of apolipopiotein vaiiability in
lipoproteins (human)
P50HL1423707 0006 Support for arteriosclerosis center
■ Drug treatment of familial hyperbetalipopioteinemia
(human)
379
ROIHL 14313 0/ Apoproteins ot triglyceride iich
lipoproteins (human, squiiiel monkeys. lats)
ROIHL 149900/ lipid tiansport in avian species
(chickens)
P50HL 15062 0/ 0009 Study of lipoproteins, arteiy wall,
and atherosclerosis Plasma lipoprotein biosynthesis
(Rhesus monkeys)
P50HL 15062 0/ 0019 Study ol lipoproteins, arteiy wall,
and atherosclerosis Factois regulating lipoprotein smooth
muscle cell inteiaction (monkey)
P50HL 15103 07 0014 A/S SCOR Eaily natuial histoiy ol
arteiiosclerosis Biochemistiy ot atherosclerotic lesions
(monkeys, human, cattle)
ROIHL 15263 06 Lecithin-Cholesterol acetyllranslerase
(human. labbits)
ROIHL 15308 07 Assays foi peptides of lipoproteins
(human)
* ROIHL 15427 06 Secretion ot plasma lipoproteins (rats)
ROIHL 1564806 Lipid metabolism -Tiansport by lateral
diffusion (human, rabbit, cattle)
ROIHL 1594905 Lipoprotein metabolism in relation to
atherosclerosis (human, baboons)
ROIHL 1621905 Mechanisms of atherogenesis in chronic
uremia (human. lats)
ROIHL 1651204 Lipoprotein metabolism and hoimonal
regulation (chickens)
P60HL 17269-04 0001 National heart and blood vessel
research and demonstration center Atherosclerosis-
Arterial pathology and plasma lipids (human)
P60HL 17269-04 0011 National heart and blood vessel
research and demonstiation center - Lipoprotein structure
laboratoiy (human)
P60HL 17269 04 0013 National heart and blood vessel
research and demonstiation center - Peptide synthesis
laboratoiy (human)
P60HL 17269-04 0045 National heart and blood vessel
research and demonstration centei Regulation of
hpogencsis in hypeilipopioteinemia (human, tissue culture)
P60HL-17269-04 0048 National heart and blood vessel
research and demonstiation center ■ Atherosclerosis -
Lipoproteins and the arterial wall (human)
** ROlHL-17463-03 Composition and structure of plasma
lipoproteins (human, rabbits)
POlHL-18574-03 0004 Lipoprotein methodology and
biomedical applications - Fine structure and metabolism of
hpoprotcins-EM studies (guinea pigs)
POlHL-18574-03 0005 Lipoprotein methodology and
biomedical applications - Structure and function of
lipoproteins
POlHL-18574-03 0006 Lipoprotein methodology and
biomedical applications - Lipoprotein transformation,
lipolytic enzymes, diet and lipid lowering agents
*• ROlHL-18687-03 Pathophysiology of genetic
hypertriglycerinemias (human)
ROlHL-18705-03 Regulation of plasma triglyceride
metabolism (lats)
ROlHL-19056-03 Blood triglycerides and lipoprotein lipase
in the lung (rats)
** ROlHL-19084-03 Structure and function of seium
lipoproteins (human)
*• ROlHL-19095-03 Laser spectroscopy of lipoproteins
(human)
** ROlHL-19168-03 Biosynthesis of plasma lipoprotein (rats,
rabbits)
ROlHL-19175-03 Pituitary modulation of micro-and macro-
vascular disease (human, rats)
ROlHL-19250-03 Mechanism of plasma cholesterol
esteiification (human)
ROlHL-20391-03 Polydispeise LDL-Stiucture, metabolism
and function (human)
** ROlHL-20397-03 VLDL-TG metabolism in diabetes mellitis
(human, rat)
R01HL-204 18-03 Serum cholesterol binding reserve in
diabetes (human)
** ROIHL 207 12-02 Characterization of the B proteins of
serum lipoproteins (human)
*" ROlHL-20954-02 Hyperlipoproteinemia (rats, human)
ROlHL-21303-02 Collagen synthesis by cultured human
vascular cells
ROlHL-22053-02 The disordered lipid metabolism of
diabetes mellitus (chickens, mammals, human)
** ROlHL-22367-01 Estrogen receptors in very low density
lipoproteins (chicken livers)
ROlHL-22618-01 Role of apolipoproteins in
hypertriglyceridemia (human)
POlHL-226 19-01 0011 Cellular mechanisms of heart
failure - Reaction of lipoproteins and apolipoproteins with
lipoprotein lipase (cattle)
** POlHL-22619-01 0012 Cellular mechanisms of heart
failure - Apolipoproteins in hypertriglyceridemia (human)
POlHL-22633-01 0002 Cellular and molecular biology of
lipoprotein metabolism - Sterol metabolism in tissue
culture cells
** ROlHL-22748-01 Effect of bile sequestration on VLOL
metabolism (human)
ROlHL-22812-01 Regulation of hepatic production of HDL
(rats)
R01HL-23945-06 Pathologic effects on cells of modified
lipoproteins (rats, human)
LIPOPROTEINS TRANSPORT
SEE PROTEINS TRANSPORT
uv
LIPOSOMES
S(( cm COMPONfNIS. lIPOSOMtS
LIPOTROPIC FACTORS
ROIHI 12085 10 tipopioleincaibohydiale metabolum
(human. lals)
P50HL 14197 07 0006 Support (oi center ol research on
arteiiosclerosis Diets and diugs atlccting lipid
metabolism (human)
ROIHI 18692 03 Glycosaminoglycans and lipoprotein', ol
human plasma
LIPOTROPIN, PITUITARY
SEE LIPID MOBILIZING FACIORS PITUITARY
LIPOXIDASE
SEE OXYGENASES. LIPOXYGENASE
LIPOXYGENASE
SEE OXYGENASES, LIPOXYGENASE
LIQUID BREATHING
SEE RESPIRATORY FUNCTION, LIQUIDS BREATHING
LIQUID CRYSTALS
SEE PHYSICAL PROPERTIES. CRYSTALS. LIQUID
LIQUID DYNAMICS
SEE PHYSICAL PROPERTIES. FLUID DYNAMICS (GENERAL)
LIQUID FLOW
SEE PHYSICAL PROPERTIES. FLUID FLOW
LIQUID FLOW IMPEDANCE
SEE PHYSICAL PROPERTIES. FLUID FLOW IMPEDANCE
LIQUID STATE
SEE PHYSICAL PROPERTIES. FLUID STATE
LITERATURE SURVEY
SEE PUBLICATIONS. LITERATURE SURVEY
LITHIUM
** P01HL07896-15 0029 Environmental biomedical research
program - Oxygen-helium diving resulting in high pressure
nervous syndrome (human, animals)
** POlHL-07896-15 0030 Environmental biomedical research
progiam - Narcosis caused by inert gases at raised
pressures (human, animals)
POlHL-12738-10 0035 Physiologic pharmacology and its
clinical applications - Function and dysfunction of the
sinoatrial node (human)
P60HL-15169-05 0018 Support for centci foi sickle cell
disease - Studies on sickle cell disease (human, lats,
dogs)
ROlHL-19653-03 Circulatory system effects of angiotensin
analogs (lats)
R01HL-20725-02 Mechanisms and cellulai functions of ion
transport
R01HL-2I136-02 Ion activities and transport in cardiac
muscle cells (sheep)
Transmembrane movements (barnacles.
LIVER
ROlHL-00082-30
frogs, rats)
ROlHL-07723-15 Reflex control of vascular capacitance in
shock
ROIHL 10940-13 Lipid transport (rabbits, cattle, chickens)
ROlHL-13399-16 Heme piotein structure and function
(human, horse, plants, bacteria)
ROlHL-15125-07 Molecular pathology of genetic disorders
in man
ROlHL-15427-06 Secretion of plasma lipoproteins (rats)
ROlHL-19223-03 Control of cholesterogenesis in leukocytes
and liver (rats, human)
LIVER CELLS
POlHL-06285-18 0205 Cardiovascular-respiratory
physiology and biochemistry Assimilation of cholesterol in
chylomicrons and VLDL (rabbits)
POlHL-08682-15 0020 Regulation of the cardiovascular
system - Hepatic metabolic basis of shock (rat)
POlHL-09011-15 0002 A research and resource program
in blood - Biosynthesis of fibrinogen (dogs)
** POlHL-09011-15 0015 A research and resource program
in blood - Regulation of synthesis and transport of diverse
proteins in liver (rats)
ROlHL-09610-14 Control of cholesterol metabolism-Bile
acid tiansport
ROlHL-10567-12 Erythropoietin -Immunoassay and
chaiacteiization (dogs)
ROlHL-12745-10 Enzymes and inhibitors of cholesterol
biosynthesis (rats, human, swine)
R01HL-13193-09 Pathophysiology of post-traumatic and
shock states (rodents, dogs)
ROlHL-14990-07 Lipid transport in avian species
(chickens)
ROlHL-16445-05 Regulation of plasma protein
biosynthesis (rats, rabbits)
POlHL-17419-04 0006 Studies on mechanisms of
hemostasis - Effect of hormones, drugs and other agents
on fibrinogen synthesis (chick)
ROlHL-20070-02 Alpha-l-antitrypsin deficiency (human,
hamsters)
ROlHL-20577-03 The mechanism of action of vitamin K
(contd)
•Excludes routine methodology OR covers only general praiects which preclude
"Onented significantly to above subiect.
indexing at the specific level.
M Grant has subproieds describing specific research aspects.
See Appendix (or investigators name and grant number.
Intravascular redistribution of blood
Pituitary-adrenergic-ovarian vasomotor
IIV
LIVER CEILS, KUPFFER CELLS
POlHL-08682-15 0019 Regulation of the cardiovascular
system - Hepatic immunophysiology and host-defense in
shock (rat, dog, human)
LIVER CIRCULATION
ROlHL-03181-21 0029 Hemodynamics as applied to
surgical problems - Indocyanine green clearance for
estimation of hepatic blood flow (human)
ROlHL-10384-13 Blood flow and nucleotide metabolism
(animals)
ROlHL-10612-13 0020 Humoral factors In heart failure
and hypertension - The control of renin release in the dog
R0IHL1190112 0013 Effects of metabolic surgery on
the hyperlipidemias - Human cholesterol and bile acids
dynamics-Meal bypass
ROlHL-13341-06 Lymph -An indication of splanchnic tissue
respiration (dogs, human, rats)
ROlHL-15607-06 Physiological control of splanchnic
circulation (dogs)
ROIHL-15655-05 Blood flow and gas exchange in placenta
and lungs (sheep) rabbits)
ROlHL-18020-04 Splanchnic hemodynamics In man
ROlHL-18096-04 Vasoactive agents in splanchnic viscera
(primates, dogs)
R01HL-2037I-02
volume (dogs)
ROlHL-20685-02
interaction (dogs)
ROlHL-21498-02 Pathophysiology of edema (rats, cats)
ROlHL-22506 01 Hemodynamics of the clinical
hypertensions
ROlHL-22977-01 Role of vasoconstrictor mechanisms in
heart failure (human, dogs)
ROlHL-23604-01 Hepatic microvascular regulatory
mechanisms (rat)
LIVER CIRCULATION, PORTAL VEIN
ROlHL-1190112 0004 Effects of metabolic surgery on
the hyperlipidemias - Ileal bypass-Cholesterol dynamics
studies (rats, rabbits, dogs)
ROlHL-1190112 0015 Effects of metabolic surgery on
the hyperlipidemias - Portacaval shunt for cholesterol
reduction (dogs, rabbits)
ROlHL-1600308 Sources and roles of calcium in smooth
muscle excitation (rats)
LIVER CIRCULATION, VENOUS BYPASS OF LIVER
" R01HL1190112 0015 Effects of metabolic surgery on
the hyperlipidemias - Portacaval shunt for cholesterol
reduction (dogs, rabbits)
ROlHL-13341-06 Lymph-An indication of splanchnic tissue
respiration (dogs, human, rats)
ROlHL-1594905 Lipoprotein metabolism in relation to
atherosclerosis (human, baboons)
ROlHL-18020-04 Splanchnic hemodynamics in man
** ROlHL-20183-02 Portacaval shunt as treatment for
hyperlipemia (pigs)
LIVER CIRCULATORY DISORDERS
ROlHL-03181-21 0020 Hemodynamics as applied to
surgical problems - Blood flow measurement-Cardiac
output and regional flows (dogs)
ROlHL-13341-06 Lymph-An indication of splanchnic tissue
respiration (dogs, human, rats)
LIVER CIRCULATORY DISORDERS, PORTAL
HYPERTENSION
SEE ALSO GASTROINTESTINAL CIRCUUTORY DISORDERS,
ESOPHAGEAL VARICES
ROlHL-18020-04 Splanchnic hemodynamics in man
ROlHL-20685-02 Pituitary-adrenergic-ovarian vasomotor
interaction (dogs)
ROlHL-21498-02 Pathophysiology of edema (rats, cats)
LIVER CIRRHOSIS
SEE LIVER DISORDERS, LIVER CIRRHOSIS
LIVER DISORDERS
SEE ALSO JAUNDICE
SEE ALSO LIVER METABOLISM
SEE ALSO METABOLIC DISORDERS (INBORN), PORPHYRIA
P01HL08899-14 0061 Tolerance to respiratory gases in
health and disease - Hepatic oxygenation and secretory
functions (rats, dogs)
ROlHL-10582-12 Thrombosis and hemostasis -Analysis,
methods and standards (human, cattle, venom)
ROIHL 11901-12 0001 Effects of metabolic surgery on
the hyperlipidemias - Partial ileal bypass (human)
ROlHL-17752-03 Purified human clotting factor IX-
Immunologic studies (human)
R01HL-20070-02 Alpha-l-antiltypsin deficiency (human,
hamsters)
RGlHL-20092-02 Structural and biological properties of
fibrinogen (human, rabbits)
ROlHL-21 159-02 Pathophysiological effects of hypoxia
(rats)
R01HL-2140401 Raman spectroscopy of erythrocyte and
model membranes (human)
ROlHL-21756-11 Vascular disease-Cytochemistry and
ultrastructure (human, rats, mice, hamsters)
ROlHL-224 56-01 Lipoproteins in bioregulation of the
immune response (mice, human)
330
LIVER DISORDERS, FATTY LIVER
ROlHL-02965-22 Metabolism of plasma lipoproteins (rats,
chickens, human)
ROlHL-06221-17 Composition and structure of plasma
lipoproteins (human, turkeys, baboons)
R01HL19I68-03 Biosynthesis of plasma lipoprotein (rats
rabbits)
ROlHL-23945-06 Pathologic effects on cells of modified
lipoproteins (rats, human)
LIVER DISORDERS, HEPATIC COMA-
ENCEPHALOPATHY
ROlHL-1 1901-12 0015 Effects of metabolic surgery on
the hyperlipidemias Portacaval shunt for cholesterol
reduction (dogs, rabbits)
LIVER DISORDERS, HEPATITIS
NOlHB-42971-12 Chimpanzees for hepatitis research
ROlHL-06221-17 Composition and structure of plasma
lipoproteins (human, turkeys, baboons)
" P01HL-11310-12 0095 Mechanisms of cardiovascular
disease - Blood and transfusion disorders (human, rats,
monkeys)
R01HL-20070-02 Alpha 1-antitrypsin deficiency (human,
hamsters)
ROlHl-23945-06 Pathologic effects on cells of modified
lipoproteins (rats, human)
LIVER DISORDERS, HEPATITIS SERUM
SEE ALSO IMMUNOLOGY, ANTIGENS VIRAL, HEPATITIS B
ANTIGEN (HBAG)
SEE ALSO VACCINES, VIRAL, HEPATITIS, SERUM
SEE ALSO VIRUSES, HEPATITIS
SEE ALSO VIRUSES, HEPATITIS B VIRUS (HBV)
** NOlHB-62908-07 Maternal to infant transmission of
hepatitis B (human)
M P01HL09011-15 A research and resource program in
blood
" POlHL-090 11-15 0005 A research and resource program
in blood - Characterization of hepatitis-B antigen and the
cause of serum hepatitis (human)
** P01HL09011-15 0018 A research and resource program
in blood - Hepatitis B in normal populations-Epidemiology.
risk factors and transmission
** POlHL-09011-15 0020 A research and resource program
in blood - Passive immunization in the prevention of
transmission of hepatitis B (human)
** POlHL-09011-15 0023 A research and resource program
in blood - Evaluation of hepatitis B vaccine in endemic
settings (human)
M POlHL-15596-05 Coagulation, fibrinolysis, hemostasis and
hepatitis
** POlHL-15596-05 0016 Coagulation, fibrinolysis,
hemostasis and hepatitis - Hepatitis-B antigen in whole
blood, plasma and plasma fractions (human, monkeys)
** P60HL- 17269-04 0035 National heart and blood vessel
research and demonstration center - Blood resources-
Research program in viral hepatitis (human)
** ROlHL-20856-02 Platelet transfusions-Usage and
complications (human)
LIVER DISORDERS, HEPATITIS VIRAL HUMAN
SEE ALSO LIVER DISORDERS, HEPATITIS SERUM
SEE ALSO VIRUSES, HEPATITIS
** P60HL-1 7269-04 0035 National heart and blood vessel
research and demonstration center - Blood resources-
Research program in viral hepatitis (human)
ROlHL-20856-02 Platelet transfusions-Usage and
complications (human)
ROlHL-22838-01 Post-transfusion hepatitis In newborn
children
ROlHL-23945-06 Pathologic effects on cells of modified
lipoproteins (rats, human)
UVER DISORDERS, HEPATORENAL SYNDROME
SEE ALSO METABOLIC DISORDERS INBORN, CEREBRO-
HEPATO-RENAL SYNDROME
ROlHL-18624-03 Study of kinins in hypertension and other
diseases (human)
LIVER DISORDERS, LIVER CIRRHOSIS
SEE ALSO LIVER DISORDERS, HEPATORENAL SYNDROME
SEE ALSO METABOLIC DISORDERS INBORN,
HEPATOLENTICULAR DEGENERATION
ROlHL-03181-21 0029 Hemodynamics as applied to
surgical problems - Indocyanine green clearance for
estimation of hepatic blood flow (human)
POlHL-0889914 0027 Tolerance to respiratory gases in
health and disease Effects of high oxygen pressures on
ethanol metabolism (human)
ROlHL-13341-06 Lymph-An indication of splanchnic tissue
respiration (dogs, human, rats)
R01HL17462-03 Role of glycosphingolipids in platelet
aggregation (rats, human, dogs)
ROlHL-17551-04 Biosynthesis and metabolism of
procollagen (human, monkeys, mice)
ROlHL-1 77 11-05 Mechanism of hypoxic regulation of lung
circulation (rats, cats, guinea pigs)
ROlHL-18020-04 Splanchnic hemodynamics in man
ROlHL-18624-03 Study of kinins in hypertension and other
diseases (human)
ROlHL-19225-02 0004 Types and mechanims of
pulmonary hypertension - Structural changes in human
pulmonary circulation (human, animals)
LIV
ROlHL-19428-03 Role of angiotensin sensitivity in renin
release (human)
ROlHL-19839-09 Factors in youth predisposing to chronic
diseases (former college students)
R01HL-22051-01 Role of angiotensin II in vasopressin
release (human)
LIVER DISORDERS, LIVER FAILURE
ROlHL-1 1901-12 0018 Effects of metabolic surgery on
the hyperlipidemias - Jejunoileal bypass -Postoperative
complications (human)
LIVER DISORDERS, TOXIC LIVER DISORDERS,
HEPATOTOXINS
** POlHL-06370-17 0006 Cardiopulmonary and renal
pathology research center - Chemical basis of
ultrastructural changes in disease (rats)
LIVER DISORDERS CHEMOTHERAPY
SEE ALSO BILIARY TRACT DISORDERS CHEMOTHERAPY
SEE ALSO LIVER PHARMACOLOGY
ROIHL- 18020-04 Splanchnic hemodynamics in man
R23HL-22882-01 Modulation by disease of effect of
furosemidc in man
LIVER DISORDERS DIAGNOSIS (INCL EXAMS)*
** R01HL03181-21 0029 Hemodynamics as applied to
surgical problems - Indocyanine green clearance for
estimation of hepatic blood flow (human)
ROlHL-06221-17 Composition and structure of plasma
lipoproteins (human, turkeys, baboons)
LIVER EXAMINATIONS
SEE LIVER DISORDERS DIAGNOSIS (INCL EXAMS)*
LIVER FAILURE
SEE LIVER DISORDERS, LIVER FAILURE
LIVER FUNCTION
SEE ALSO BILE ACIDS AND SALTS, ENTEROHEPATIC
CIRCULATION
ROlHL-02254-23 Blood coagulation and hemorrhagic
disease (human, animals)
P01HL06835-17 0018 Cardiovascular disease - Fatty
acid concentration (rats)
P01HL08899-14 0027 Tolerance to respiratory gases In
health and disease - Effects of high oxygen pressures on
ethanol metabolism (human)
POlHL-08899-14 0055 Tolerance to respiratory gases In
health and disease - Oxygen effects on organ functions-
Extension of tolerance
** POlHL-08899-14 0061 Tolerance to respiratory gases in
health and disease - Hepatic oxygenation and secretory
functions (rats, dogs)
P01HL09011-15 0021 A research and resource program
in blood - Regulation of transfer RNA methylating enzymes
(rats, E coll)
R01HL11901-12 0012 Effects of metabolic surgery on
the hyperlipidemias - Ileal bypass-Animal atherosclerosis
implications (pigeons, dogs, rabbits)
ROlHL-1 1901-12 0013 Effects of metabolic surgery on
the hyperlipidemias • Human cholesterol and bile acids
dynamics-lleal bypass
POIHL- 18208-04 0003 Center for the study of blood cell
rheology - Bone marrow microcirculation (rats, mice)
ROlHL-19322-03 Role of pituitary hormones In the action
of vitamin K (rats)
ROlHL-19898-03 Desferrioxamine therapy In thalassemia
(dogs, rats, children)
ROlHL-21 11202 Aldosterone binding, clearance, and
secretion in man
R23HL-21411-02 Control of extracellular lysosomal
hydrolase levels (rats)
ROlHL-21431-02 Factor II antigen and coagulant activity
(human, animals)
ROlHL-23945-06 Pathologic effects on cells of modified
lipoproteins (rats, human)
LIVER METABOLISM
SEE ALSO LIVER PHARMACOLOGY
ROlHL-05360-19 Cholesterol biosynthesis and its control
Metabolism of neutral sterols (rats,
•Excludes routine methodology OR covers only general ptoiects which preclude indexing
Oriented significantly to alxjve subject.
at tile specific level.
M Grant has subprojects describing specific research aspects
See Appendix for investigator's name and grant number.
in liver (rats)
ROlHL-07878-16
rabbits)
ROlHL-08506-15 Lipemia-carbohydrate and glyceride
metabolism (human, rats)
POlHL-08682-15 0019 Regulation of the cardiovascular
system - Hepatic immunophysiology and host-defense in
shock (rat, dog, human)
POlHL-08682-15 0020 Regulation of the cardiovascular
system - Hepatic metabolic basis of shock (rat)
R01HL10612-13 0020 Humoral factors in heart failure
and hypertension - The control of renin release in the dog
R01HL-1190M2 0001 Effects of metabolic surgery on
the hyperlipidemias - Partial ileal bypass (human)
R01HL11901-12 0004 Effects of metabolic surgery on
the hyperlipidemias - Ileal bypass -Cholesterol dynamics
studies (rats, rabbits, dogs)
ROlHL-12138-08 Nutritional regulation of enzyme activity
(rats, human)
ROlHL-12745-10 Enzymes and inhibitors of cholesterol
biosynthesis (rats, human, swine)
ROlHL-13193-09 Pathophysiology of post-traumatic and
shock states (rodents, dogs)
(contd)
Cholesterol and lipoprotein metabolism
Biosynthesis of plasma lipoprotein (rats,
VLOLTG metabolism in diabetes mellitis
LIV
"• R01HL1330209 UptaKe and metabolism ol lipids by the
liver (rats)
P50HI 14164 O; 0037 A/S SCOR Comparative and
•xpanmantal atherosclerosis Genetic control ol plasma
cholesterol Interaction ol dietary tatty acid (monkey)
PSOHl 14237 07 0001 Support tor arteriosclerosis center
Role o( apolipoproteins in lipoprotein catabolism (human.
rats)
•* PSOHL 14237 07 0004 Support tor arteriosclerosis center
Synthesis, secretion ol normal, abnormal plasma
lipoproteins (rodents, monkeys)
ROIHL 14313 07 Apoproteins ot triglyceride rich
lipoproteins (human, squirrel monkeys, rats)
PMHL 15062 07 0009 Study of lipoproteins, artery wall,
and atherosclerosis Plasma lipoprotein biosynthesis
(Rhesus monkeys)
ROIHL 15797 OS Lipid metabolism and atherosclerosis in
primates (monkeys, human, squirrels)
R01HL1593006 Hormonal control of lipid and lipoprotein
synthesis (rats)
ROIHL 16364 04 Regulation of lipid biosynthesis and
transport (rats, swine. Xenopus)
ROIHL 1781805 Metabolism of cholesterol and cholesterol
in man (also rats, monkeys)
ROIHL 1821904 Regulation ot cholesterol metabolism
(rats)
R01HL19063 03
(rat hepatocytes)
" ROIHL 19168-03
rabbits)
ROIHL 2039703
(human, rat)
P50HL-2 1006-02 0003 Specialized center of research in
arteriosclerosis ■ Transport of vitamin A in plasma (human,
rat)
ROlHL-21159-02 Pathophysiological effects of hypoxia
(rats)
ROlHL-21996-01 Alteration of digitalis and aldosterone
disposition (rats, rabbits, mice, dogs)
** R01HL-22812-01 Regulation of hepatic production of HDL
(rats)
ROlHL-23595-01 Experimental emphysema -Depression oi
protease inhibitors (rats, hamsters)
LIVER PHARAAACOLOGY
SEE ALSO BILIARY TRACT PHARMACOLOGY
SEE ALSO LIVER DISORDERS CHEMOTHERAPY
R01HL1593006 Hormonal control of lipid and lipoprotein
synthesis (rats)
ROlHL-20859-02 Beta adrenergic catecholamine receptor
ROlHL-2 1476-02 Anticoagulant drug absorption
interactions (rats)
UVER TOXINS
SEE LIVER DISORDERS, TOXIC LIVER DISORDERS,
HEPATOTOXINS
UVER VENOUS BYPASS
SEE LIVER CIRCULATION. VENOUS BYPASS OF LIVER
IMS
SEE IMIDAZOLES. LEVAMISOLE
LOCAL ANESTHESIA
SEE SENSORY DEPRESSION. ANESTHESIA CONDUCTION,
LOCAL
LOCAL ANESTHETICS
SEE NEUROPHARMACOLOGICAL AGENTS. ANESTHETICS,
LOCAL
LOCAL HORMONES
SEE NEUROTRANSMinERS (GENERAL)
LOCOMOTION IN SINGLE CELL AND
MULTICELLULAR MICROORGANISMS
SEE CELL COMPONENTS, CILIARY MOVEMENT
SEE CELL MOVEMENT
LONDON-VAN DER WAAL'S FORCES
SEE MOLECULAR INTERACTIONS NONBONDING
LONG CHAIN COMPOUNDS
SEE CHEMICAL STRUCTURE. CHAIN LENGTH
LONGEVITY
SEE AGING. LONGEVITY
LONGEVITY (CELLULAR)
SEE CELL AGE
LONGITUDINAL STUDY
SEE POPULATION STUDIES HUMAN. LONGITUDINAL STUDY
LONGITUDINAL STUDY, ANIMAL
SEE POPULATION STUDIES ANIMAL. LONGITUDINAL STUDY
LOW BIRTH WEIGHT ANIMALS
SEE AGE (ANIMAL). INFANTS PREMATURE AND LOW BIRTH
WEIGHT
LOW BIRTH WEIGHT, HUMAN
SEE CHILDREN. INFANT PREMATURE AND LOW BIRTH WEIGHT
LOW DENSITY LIPOPROTEINS
SEE LIPOPROTEINS BLOOD. LDL
331
LOW FIBER DIET
Sff NUIRIIION. DICIARY CONSTITUENTS, DIETARY RESIDUES
riBFRS
LOW INCOME GROUPS
SEE SOCIOECONOMICS. INCOME. LOW INCOME GROUPS
LOW RENIN HYPERTENSION
SEE CAROIOVASCUUR DISORDERS. HYPERTENSION
(SYSTEMIC). ANGIOTENSIN RENIN ALDOSTERONE
ASSOCIATED
LOW RESIDUE DIET
SEE NUTRITION, DIETARY CONSTITUENTS, DIETARY RESIDUES
FIBERS
LOW SALT DIET
SEE NUTRITION, DIET THERAPEUTIC, SALT RESTRICTED
LOW TEMPERATURE PRESERVATION AND
STORAGE
SEE TEMPERATURE, CRYOSCIENCES, LOW TEMPERATURE
PRESERVATION AND STORAGE
LOWER NEPHRON NEPHROSIS
SEE KIDNEY DISORDERS, NEPHROSIS LOWER NEPHRON
LRF
SEE PITUITARY-OIENCEPHALON HORMONES, LH RELEASING
FACTOR
LTF (LYMPHOKINES)
SEE HYPERSENSITIVITY, LYMPHOKINES. LYMPHOCYTE
TRANSFORMING FACTORS
LUNG
SEE RESPIRATORY SYSTEM, LUNG
LUNG ALVEOLUS
SEE RESPIRATORY SYSTEM, LUNG ALVEOLUS
LUNG CIRCULATION
SEE RESPIRATORY CIRCUUTION, PULMONARY CIRCULATION
LUNG DISORDERS
SEE RESPIRATORY DISORDERS, LUNG DISORDERS (GENERAL)
LUNG NEOPLASMS
SEE NEOPLASMS OF RESPIRATORY SYSTEM. LUNG
NEOPLASMS
LUNG PRESERVATION
SEE RESPIRATORY SYSTEM PRESERVATION, LUNG
PRESERVATION
LUNG PRESSURE
SEE RESPIRATORY FUNCTION. RESPIRATORY AIRWAY
PRESSURES
LUNG SCANNING
SEE RESPIRATORY VISUALIZATION. LUNG SCANNING*
LUNG TOXINS
SEE RESPIRATORY DISORDERS. RESPIRATORY SYSTEM
TOXINS
LUNG TRANSPLANTATION
SEE RESPIRATORY SYSTEM TRANSPLANTATION, LUNG
TRANSPUNTATION
LUNG TUBERCULOSIS
SEE BACTERIAL DISEASES. ACTINOMYCETALES INFECTIONS,
TUBERCULOSIS
LUPUS ERYTHEMATOSUS SYSTEMIC
SEE CONNECTIVE TISSUE DISORDERS. LUPUS
ERYTHEMATOSUS SYSTEMIC
LUPUS PERNIO
SEE NEOPLASMS REUTEO INTEREST. SARCOIDOSIS
LUTEINIZING HORMONE RELEASING FACTOR
SEE PITUITARY-DIENCEPHALON HORMONES. LH RELEASING
FACTOR
LUTEOTROPIN (PITUITARY)
SEE PITUITARY-DIENCEPHALON HORMONES, PROLACTIN
LYMPH
SEE BLOOD AND RE SYSTEM. LYMPH
LYMPH FLOW
SEE BLOOD AND RE SYSTEM. LYMPH FLOW
LYMPH NODES
SEE BLOOD AND RE SYSTEM. LYMPHATIC TISSUE. LYMPH
NODES
LYMPHATIC CIRCULATION
SEE BLOOD AND RE SYSTEM. LYMPHATIC CIRCULATION
(GENERAL)
LYMPHATIC DUCT DRAINAGE
SEE BLOOD AND RE SYSTEM. LYMPHATIC DUCT DRAINAGE
LYMPHATIC TISSUE
SEE BLOOD AND RE SYSTEM. LYMPHATIC TISSUE
LYMPHATIC VESSELS
SEE BLOOD AND RE SYSTEM, LYMPHATIC CIRCULATION
(GENERAL)
M P
LYMPHOCYTE ACTIVATING FACTOR
SfF MIIOGENS
LYMPHOCYTE ACTIVATION
SEE IMMUNITY. CfllUIAR. LYMPHOCYTE ACflVATION.
IRANSFORMATION AND PROIIftRATION
LYMPHOCYTE DEPLETION THERAPY
SEE BLOOD CELL DEPLETION IHERAPY, LYMPHOCYTE
DEPLETION
T LYMPHOCYTE DEPLETION THERAPY
SEE BtOOO CELL DEPLETION THERAPY, T LYMPHOCYTE
DEPLETION
LYMPHOCYTE PRODUCTS
SEE HYPERSENSITIVITY, LYMPHOKINES
LYMPHOCYTE PROLIFERATION
SEE IMMUNITY, CELLUUR, LYMPHOCYTE ACTIVATION,
TRANSFORMATION AND PROLIFERATION
LYMPHOCYTE RECEPTORS AND RECOGNITION
SEE IMMUNITY, CELLUU^R, LYMPHOCYTE ACTIVATION,
TRANSFORMATION AND PROLIFERATION
LYMPHOCYTE TRANSFORMATION
SEE IMMUNITY, CELLULAR, LYMPHOCYTE ACTIVATION,
TRANSFORMATION AND PROLIFERATION
LYMPHOCYTE TRANSFORMING FACTORS
SEE HYPERSENSITIVITY, LYMPHOKINES, LYMPHOCYTE
TRANSFORMING FACTORS
LYMPHOCYTES
SEE BLOOD CELLS, LYMPHOCYTES
B LYMPHOCYTES
SEE BLOOD CELLS, B LYMPHOCYTES
T LYMPHOCYTES
SEE BLOOD CELLS, T LYMPHOCYTES
LYMPHOCYTIC LYMPHOMA
SEE NEOPLASMS OF BLOOD AND RE SYSTEM,
LYMPHOSARCOMA
LYMPHOGRANULOMA VENEREUM AGENT
SEE CHLAMYDIA, LYMPHOGRANULOMA VENEREUM AGENT
LYMPHOGRANULOMATOSIS BENIGN
SEE NEOPWSMS RELATED INTEREST, SARCOIDOSIS
LYMPHOGRANULOMATOSIS, MAUGNANT
(HODGKIN'S)
SEE NEOPUSMS OF BLOOD AND RE SYSTEM, HODGKIN'S
DISEASE
LYMPHOID TISSUE
SEE BLOOD AND RE SYSTEM, LYMPHATIC TISSUE
LYMPHOKINES
SEE HYPERSENSITIVITY, LYMPHOKINES
LYMPHOMA
SEE NEOPLASMS OF BLOOD AND RE SYSTEM, LYMPHOMA
LYMPHOMATOSIS NEURAL AVIAN
SEE NERVOUS DISORDERS CENTRAL, MAREK'S DISEASE
LYMPHOSARCOMA
SEE NEOPLASMS OF BLOOD AND RE SYSTEM,
LYMPHOSARCOMA
LYMPHOSARCOMA, PLEOMORPHIC
SEE NEOPLASMS OF BLOOD AND RE SYSTEM. HODGKIN'S
DISEASE
LYSINE
SEE DIAMINO ACIDS. LYSINE
LYSINE PEPTIDES
SEE PEPTIDES, HOMOPEPTIDES. LYSINE PEPTIDES
LYSOKINASE
SEE BLOOD COAGULATION. LYSOKINASE
LYSOLECITHIN
SEE PHOSPHOLIPIDS, PHOSPHOGLYCERIDES, LYSOLECrTHIH
LYSOPHOSPHATIDYLCHOLINE
SEE PHOSPHOLIPIDS, PHOSPHOGLYCERIDES, LYSOLECrTHIN
LYSOPHOSPHOLIPIDS
SEE PHOSPHOLIPIDS, LYSOPHOSPHOLIPIDS
LYSOSOMAL DISORDERS
SEE METABOLIC DISORDERS INBORN. LYSOSOMAL
DISORDERS
LYSOSOMAL DYSFUNCTION IN DISORDERED
LEUKOCYTE PHAGOCYTE ACTIVITY
SEE BLOOD AND RE DISORDERS. LEUKOCYTE DISORDERS.
PHAGOCYTE DYSFUNCTION (GENERAL)
LYSOSOMES
SEE CELL COMPONENTS. LYSOSOMES
LYSOZYME
SEE CARBOHYDRASES. LYSOZYME
(cmtd)
•Excludes routine methodotogy OR covers only general projects which preclude i
"Ofiemed significantly to above subject.
ndexing at the specific level.
M Grant has subprojeds describing specific research aspects.
See Appendix for investigator's name and grant number.
■n¥lrtrtOfvnr->1i'« ifi ■ I'liu u i
AAAC
M PROTEIN
SEE IMMUNOLOGY, ANTIGENS BACTERIAL, M PROTEIN
MACACA
SEE MAMMALS, PRIMATES, MONKEYS AND APES
(ANTHROPOIDS, NON-HUMAN), OLD WORLD MONKEYS
MACACA SP*
MACACA MULATTA
SEE MAMMALS, PRIMATES, MONKEYS AND APES
(ANTHROPOIDS, NON-HUMAN), OLD WORLD MONKEYS
MACACA SP , MACACA MULAHA*
MACACQUES
SEE MAMMALS, PRIMATES, MONKEYS AND APES
(ANTHROPOIDS, NON-HUMAN), OLD WORLD MONKEYS
MACACA SP*
MACROGLOBULINS
SEE GLOBULINS, MACROGLOBULINS
AAACROMOIECULES
SEE MOLECULES, MACROMOLECULES
MACROPHAGE AGGREGATION FACTOR
SEE HYPERSENSITIVITY, LYMPHOKINES. MACROPHAGE
AGGREGATION FACTOR
MACROPHAGES
SEE BLOOD AND RE SYSTEM, MACROPHAGES
MACROPHAGES, ALVEOLAR
SEE RESPIRATORY SYSTEM, ALVEOLAR MACROPHAGES
AAACULA DENSA
SEE KIDNEY, RENAL TUBULES, MACULA
AAAF (LYMPHOKINES)
SEE HYPERSENSITIVITY, LYMPHOKINES, MACROPHAGE
AGGREGATION FACTOR
MAGNESIUM
SEE METALS, ALKALINE EARTH METALS, MAGNESIUM
MAGNESIUM DEFICIENCY (DEPLETION)
SEE METAL DISORDERS AND IMBALANCES, MAGNESIUM
DEFICIENCY
MAGNETIC BALANCE METHODS
SEE PHYSICAL PROPERTIES, DENSITY, MAGNETIC
SUSPENSION METHODS*
MAGNETIC CIRCULAR DICHROISM
SEE OPTICS, DICRHOISM CIRCULAR MAGNETIC*
MAGNETIC COLLOIDS
SEE PHYSICAL PROPERTIES, COLLOIDS, MAGNETIC
/MAGNETIC DENSITY-VOLUME METHODS
SEE PHYSICAL PROPERTIES, DENSITY, MAGNETIC
SUSPENSION METHODS*
MAGNETIC FIELDS
SEE ELECTRICITY-MAGNETISM, MAGNETIC FIELDS
MAGNETIC RECORDING SYSTEMS
SEE BIOMEDICAL SYSTEMS AUTOMATED, MAGNETIC
RECORDING SYSTEMS
MAGNETIC RESONANCE
SEE CHEMISTRY, ANALYTICAL METHODS, SPECTROMETRY
ESR*
SEE CHEMISTRY, ANALYTICAL METHODS, SPECTROMETRY
NMR*
MAGNETIC SUSPENSION METHODS
SEE PHYSICAL PROPERTIES, DENSITY, MAGNETIC
SUSPENSION METHODS*
MAGNETOCARDIOGRAPHY
SEE HEART DISORDERS DIAGNOSIS, VECTOR
MAGNETOCARDIOGRAPHY*
MALABSORPTION SYNDROMES
SEE GASTROINTESTINAL DISORDERS, MAUBSORPTION
SYNDROMES
MALARIA
SEE PARASITIC DISEASES, PROTOZOAL INFECTIONS, MAURIA
MALATE
SEE DICARBOXYLIC ACIDS, MALIC ACID
MALATE DEHYDROGENASE
SEE OXIDOREDUCTASES, MALATE DEHYDROGENASE
MALE
SEE SEX, MALE
AAALEIMIDES
SEE PYRROLIDINEDIONES, MALEIMIDES
MALIC ACID
SEE DICARBOXYLIC ACIDS, MALIC ACID
MALIGNANT HYPERTENSION
SEE CARDIOVASCULAR DISORDERS, HYPERTENSION
(SYSTEMIC)
332
MALIGNANT LYMPHOMA
SEE NEOPUSMS OF BLOOD AND RE SYSTEM, HODGKIN'S
DISEASE
MALNUTRITION
SEE NUTRITIONAL ABNORMALITIES, MALNUTRITION (GENERAL)
MALNUTRITION (NONDIETARY)
SEE NUTRITIONAL ABNORMALITIES
MALONALDEHYDE
SEE DICARBOXYLIC ALDEHYDES, MALONALDEHYDE
MALONYL-COA SYNTHETASE
SEE CARBON-CARBON LIGASES. ACETYL-COA CARBOXYUSE
MALTASE
SEE CARBOHYDRASES, ALPHA-GLUCOSIDASE
MAAVMALS*
R01HL-I5284-06 Hemoglobin and myoglobin kinetic
studies (human, animals)
MAAAMALS, ARTIODACTYLA, CATTLE*
SEE ALSO ALBUMINS, SERUM ALBUMIN BOVINE
ROlHL-10940-13 Lipid transport (rabbits, cattle, chickens)
** ROlHL-18191-04 Models of hypoxic pulmonary
hypertension (cattle, minipigs)
NOlHV-12060-18 Tissue cultured endothelium for vascular
prosthetic devices (human, animals)
NOlHV-42960-07 Development and evaluation of cardiac
prostheses (calves)
MAAAA»ALS, ARTIODACTYLA, GOATS*
POlHL-03 174-23 0006 Mechanisms of acute vascular
reaction to injury - Atherosclerotic plaque studies using
mosaic analysis (human)
MAAAAAALS, ARTIODACTYLA, SHEEP*
** NOlHI-72900-01 Maintenance of the NHLBI sheep colony
P50HL-191 53-02 0004 SCOR -Pulmonary edemas-Eitology,
pathogenesis ■ Physical mechanisms in lung transvascular
transport -Math models (sheep)
R01HL-23980-01 Effects of digoxin therapy in nev»born
and adult sheep
MAMAAIS. ARTIODACTYLA, SWINE, MINIATURE
SWINE*
** ROlHL-18191-04 Models of hypoxic pulmonary
hypertension (cattle, minipigs)
MAAAAAALS, CARNIVORES, DOGS*
P01HL-14388-07 0217 Regulation of the circulation in
pathological states - Fluid mechanics of aortic flow (dogs,
human)
R01HL-15307-C6 Central nervous control of renin and
blood pressure (dogs)
** R01HL-15647-06 Hematopoietic studies of cyclic
hematopoiesis (dogs)
** RQ1HL-16292-05 0020 Surgery and non-obstructive
coronary insufficiency - Limitation of transthoracic ECG in
detecting subendocardial ischemia (dogs)
P50HL-17646-04 0004 Study of ischemic heart disease -
Core experimental animal laboratories
R01HL-19039-03
model (dogs)
ROlHL-19648-03
MAM
A/S SCOR -Atherosclerosis in
- Core laboratory -Animal services
rabbits)
ROlHL-21872-01
heart (dogs)
ROlHL-22281-01
Circulation studies by one vs two circuit
Myocardial protein degradation (dogs.
Myocardial perfusion in the hypertrophied
MIcroprobe analysis and metabolite
levels of ischemic mycardium (dogs)
MAAAAAALS, LAGOMORPHS*
POlHL-06664-17 0037 Cardiopulmonary function In
remediable vascular disease - Salt and water balance of
cells and tissues (rabbits)
R01HL-I5677-06 Autonomic nervous system function in
bronchial asthma (human, guinea pig, rabbit)
ROlHL-16361-03 Fibrin complexes in intermediary
coagulation (human, rabbits)
P50HL-1 7646-04 0004 Study of ischemic heart disease -
Core experimental animal laboratories
P50HL-183 18-03 0002 Pathogenesis and complications of
hypertension - Core experimental animal facility (rats,
rabbits)
MAAAMALS, PRIMATE COLONIES
ROlHL-00487-29 Vasomotor tone and venous return
(human, dogs, monkeys )
** P50HL-14164-07 0025 A/S SCOR-Comparative and
experimental atherosclerosis - Animal care resource and
laboratory animal medicine unit (monkeys, pigeons)
P50HL-141 64-07 0027 A/S SCOR-Comparative and
experimental atherosclerosis - Hyper- and
hyporesponsiveness to dietary cholesterol (squirrel monkey)
*• P50HL-14164-07 0028 A/S SCOR-Comparative and
experimental atherosclerosis - Hyper- and
hyporesponsiveness to dietary cholesterol (African green
monkey)
M P50HL-19362-02 A/S SCOR-Atherosclerosis in nonhuman
primates
P50HL-19362-02 0004 A/S SCOR-Atherosclerosis in
nonhuman primates - Selective breeding for characters
related to atherosclerosis (baboons)
•Excludes routine methodotogy OR covers only general projects which preclude indexing at the specific level
Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects
See Appendix for investigator's name and grant number.
P50HL-19362-02 0016
nonhuman primates
(baboon)
** NOlHV-62905-02 Non-human primate models of
arteriosclerosis
AAAMAAALS, PRIAAATES*
M P50HL-14164-07 A/S SCOR-Comparative and experimental
atherosclerosis
R01HL-22573-01 Treatment of post surgical
vasoconstriction (dogs, monkeys, human, rats)
AAAMMALS, PRIAAATES, MONKEYS AND APES
(ANTHROPOIDS, NON-HUMAN), GREAT APES
(PONGIDS), PAN (CHIMPANZEE)*
** NOlHB-42971-12 Chimpanzees for hepatitis research
AAAMAAALS, PRIAAATES, MONKEYS AND APES
(ANTHROPOIDS, NON-HUAAAN), NEW WORLD
MONKEYS (PLATYRHINES)*
P50HL-14164-07 0025 A/S SCOR-Comparative and
experimental atherosclerosis - Animal care resource and
laboratory animal medicine unit (monkeys, pigeons)
P50HL-14:64-07 0027 A/S SCOR-Comparative and
experimental atherosclerosis - Hyper- and
hyporesponsiveness to dietary cholesterol (squirrel monkey)
ROlHL-20384-09 Social stimulation. RNA and
cardiovascular disease (animals)
AAAMAAALS, PRIMATES, MONKEYS AND APES
(ANTHROPOIDS, NON-HUMAN), OLD WORLD
MONKEYS (CATARRHINES)*
P50HL-14164-07 0025 A/S SCOR-Comparative and
experimental atherosclerosis - Animal care resource and
laboratory animal medicine unit (monkeys, pigeons)
P50HL-14164-07 0028 A/S SCOR -Comparative and
experimental atherosclerosis - Hyper- and
hyporesponsiveness to dietary cholesterol (African green
monkey)
M P50HL-19362-02 A/S SCOR-Atherosclerosis in nonhuman
primates
P50HL-19362-02 0004 A/S SCOR-Atherosclerosis in
nonhuman primates - Selective breeding for characters
related to atherosclerosis (baboons)
P50HL-19362-02 0005 A/S SCOR-Atherosclerosis in
nonhuman primates - Hybridization to produce primate
model of atherosclerosis (baboon. Rhesus)
P50HL-19362-02 0014 A/S SCOR-Atherosclerosis in
nonhuman primates - Core laboratory-Behavior observation
and manipulation (baboon)
P50HL-19362-02 0016 A/S SCOR-Atherosclerosis in
nonhuman primates - Core laboratory-Animal services
(baboon)
NOlHV-62905-02 Non-human primate models of
arteriosclerosis
AAAMAAALS, PRIAAATES, MONKEYS AND APES
(ANTHROPOIDS, NON-HUMAN), OLD WORLD
MONKEYS, AAACACA SP.*
ROlHL-15512-06 Drug treatment of stenosing primate
atherosclerosis (rabbits, monkeys)
AAAMAAALS, PRIAAATES, MONKEYS AND APES
(ANTHROPOIDS, NON-HUMAN), OLD WORLD
MONKEYS, AAACACA SP., MACACA MULATTA*
M POlHL-18645-03 Biology of the artery wall and
atherosclerosis
** POlHL-18645-03 0001 Biology of the artery wall and
atherosclerosis - Primate arterial smooth muscle and
atherosclerosis
** POlHL-18645-03 0003 Biology of the artery wall and
atherosclerosis ■ Synthesis of connective tissue proteins by
smooth muscle cells (human, monkeys)
POlHL-18645-03 0007 Biology of the artery wall and
atherosclerosis - Lipoprotein metabolism in subhuman
primates
P50HL-19362-02 0005 A/S SCOR-Atherosclerosis in
nonhuman primates ■ Hybridization to produce primate
model of atherosclerosis (baboon. Rhesus)
NOlHV-72978-02 Development of models of hypertension
** NOlHV-72980-02 Development of models of hypertension
AAAMAAALS, RODENTS, HYSTRICOMORPHA,
GUINEA PIGS*
ROlHL-07652-14 Destruction of red blood cells in
hemolytic anemias (human, guinea pigs)
POlHL-17382-05 0002 Chemical mediators of acute
pulmonary disorders - Chemical mediators and respiratory
mechanics in guinea pigs
P50HL-17646-04 0004 Study of ischemic heart disease -
Core experimental animal laboratories
ROlHL-23624-01 Effect of drugs on ischemic cardiac cells
(dogs, guinea pigs, pigs)
AAAMMALS, RODENTS, MYOMORPHA,
HAMSTERS*
POlHL-19717-02 0002 Response of the lung to injury -
Prolyl hydroxylase, lysyl hydroxylase and lung collagen
biosynthesis (rabbits)
(contd)
MAM
MAAAMALS, RODENTS, MYOMORPHA, MICE
(LABORATORY)*
ROIHI 18163 04 Red cell membune eltects due to
otidiiiiiii agents
MAMAAAIS, RODENTS, MYOMORPHA, RATS
(LABORATORY)*
ROIHL 11901 12 0020 Eftects ot metebohc suigery on
ttie hypedipidemias leiunoileal bypass Endogenous
animal model ol obesity (lats)
P50HL 14217 08 0061 Specialized center ot research in
thrombosis Pharmacology Comparison of platelets and
vascular smooth muscle (animal)
PbOHl 17646 04 0004 Study ol ischemic heart disease
Core experimental animal laboratories
P5OHL1831803 0002 Pathogenesis and complications ol
hypertension Core experimental animal facility (rats,
rabbits)
MAMMALS, RODENTS, MYOMORPHA,
SPONTANEOUS HYPERTENSIVE RATS*
P50HL-1415908 0024 Specialized center ot research in
hypertension • Core resources (clinical, animal models)
** P01HL1438807 0167 Regulation ot the circulation in
pathological states Increased reactivity of artery vascular
muscle in spontaneously hypertensive rat
*" P01HL14388-07 0195 Regulation of the circulation in
pathological states General review of potential
pathophysiologic factors in spontaneous hypertension
** P01HLU388-07 0196 Regulation of the circulation in
pathological states - Altered vascular responsiveness in
spontaneous hypertension (rats)
*• POIHL 14388-07 0197 Regulation of the circulation in
pathological states Altered vascular reactivity in
pathogenesis ot spontaneous hypertension (rats)
** P01HL14388-07 0198 Regulation of the circulation in
pathological states - Humoral factors in vascular reactivity
in spontaneously hypertensive rats
*• P01HL14388-07 0199 Regulation of the circulation in
pathological states ■ Adrenergic stimulation in
spontaneously hypertensive rats
** POlHL-1438807 0201 Regulation of the circulation in
pathological states ■ Central sympathetic discharge in
spontaneously hypertensive rats
** POlHL-1438807 0202 Regulation of the circulation in
pathological states - Development of hypertension in
spontaneously hypertensive rats
•* P01HL14388-07 0203 Regulation of the circulation in
pathological states • Activation of sympathetic nervous
systems in spontaneously hyperactive rats
** P01HL14388-07 0204 Regulation of the circulation in
pathological states - Reflex control of vascular resistance
in spontaneously hypertensive rats
** POlHL-14388-07 0205 Regulation of the circulation in
pathological states - Pathogenesis of hypertension in
spontaneously hypertensive rats
** POlHL-14388-07 9001 Regulation of the circulation in
pathological states - Core facility for hypertensive animal
colony (rats)
R01HLI7724-03 Oral contraceptives and hypertension
(rats)
P50HL-18318-03 0002 Pathogenesis and complications of
hypertension - Core experimental animal facility (rats,
rabbits)
P50HL18318-03 0007 Pathogenesis and complications of
hypertension ■ Humoral factors and renal function in
experimental hypertension (rats)
** ROlHL-22836-01 The spontaneously hypertensive kidney
(rats)
ROlHL-22868-01 Presynaptic regulatory mechanisms in
hypertension (rats, dogs)
MAAAMARY ARTERY
SEE CARDIOVASCULAR SYSTEM, ARTERIES, liflAltflMARY
ARTERY
MAMMARY GLANDS
SEE REPRODUCTIVE SYSTEM FEMALE, MAMMARY GLANDS
MAAAAAARY TUMORS
SEE NEOPLASMS OF REPRODUCTIVE SYSTEM, BREAST
NEOPUSMS
AAAAAMOGRAPHY
SEE NEOPLASMS DIAGNOSIS. BREAST NEOPLASMS
DIAGNOSIS, MAMMOGRAPHY*
AAAMMOTROPIN
SEE PITUITARY-OIENCEPHALON HORMONES, PROUCTIN
AAAN-COMPUTER INTERACTION
SEE COMPUTER, MAN-COMPUTER INTERACTION
AAANGABEYS
SEE MAMMALS, PRIMATES, MONKEYS AND APES
(ANTHROPOIDS, NON-HUMAN), OLD WORLD MONKEYS
(CATARRHINES)*
MANGANESE (COMPOUNDS)
SEE METALS, HEAVY METALS, MANGANESE
AAANNITOL
SEE SUGAR ALCOHOLS, HEXITOLS, MANNITOL
333
MANNOSE
SIf HEXOSES. MANNOSE
MANPOWER
SEE HEALTH SCIENCES PROFESSIONS, HEAITH SCIENCES
MANPOWER
MAPPING
SEE BRAIN MAPPING
SEE GENETIC MAPPING
SEE NERVOUS SYSTEM CENTRAL. SPINAL CORD MAPPING
MAPPING OF EPICARDIUM
SEE HEART VISUALIZATION, EPICARDIAL MAPPING
MAPS
SEE PUBLICATIONS, ATLASES
MARCHIAFAVA-MICHEU SYNDROME
SEE HEMOPROTEINS, HEMOGLOBINURIA, PAROXYSMAL
NOCTURNAL
MAREK'S DISEASE
SEE NERVOUS DISORDERS CENTRAL, MAREKS DISEASE
MARFAN SYNDROME
SEE METABOLIC DISORDERS INBORN, MARFAN SYNDROME
AAARIHUANA
SEE ALKALOIDS, CANNABIS
MARINE BIOLOGY
SEE WATER ENVIRONMENT, MARINE BIOLOGY
MARKERS
SEE GENETIC MAPPING, GENETIC MARKERS
MARMOSETS
SEE MAMMALS, PRIMATES, MONKEYS AND APES
(ANTHROPOIDS, NON-HUMAN), NEW WORLD MONKEYS
(PLATYRHINES)*
MARRIAGE
SEE FAMILY, MARRIAGE
MARROW
SEE BLOOD AND RE SYSTEM, BONE MARROW
MASERS, OPTICAL
SEE OPTICS. LASERS*
MASS COMMUNICATION MEDIA
SEE INFORMATION DISSEMINATION, MASS MEDIA
AAASS DIAGNOSTIC SCREENING
SEE DIAGNOSTIC SERVICES, MASS SCREENING
MASS SPECTROMETRY
SEE CHEMISTRY, ANALYTICAL METHODS, SPECTROMETRY,
MASS*
AAAST CELL HYPERPLASIA
SEE BLOOD AND RE DISORDERS, MAST CELL HYPERPLASIA
MAST CELL NEOPLASMS
SEE NEOPLASMS OF BLOOD AND RE SYSTEM, MAST CELL
NEOPLASMS
MAST CELLS
SEE BLOOD AND RE SYSTEM, MAST CELLS
MASTERS STEP TEST
SEE CARDIOVASCULAR DISORDERS DIAGNOSIS, EXERCISE
STRESS TESTING*
AAASTOCYTOAAA
SEE NEOPLASMS OF BLOOD AND RE SYSTEM, MAST CELL
NEOPLASMS
MATERNAL AND INFANT CARE
SEE HEALTH CARE SERVICES, MATERNAL AND INFANT CARE
MATERNAL BEHAVIOR
SEE FAMILY, MATERNAL BEHAVIOR
AAATERNAL-FETAL
SEE PREGNANCY, PRENATAL STRESS
SEE PREGNANCY IMMUNOLOGY
MATERNAL NUTRITION
SEE NUTRITION, MATERNAL-FETAL NUTRITION
MATHEAAATICAL MODELS
SEE MODELS, MATHEMATICAL
MATHEMATICS, BIOMATHEMATICS (GENERAL)
SEE ALSO COMPUTER (GENERAL) INCL COMPUTER DATA
PROCESSING (GENERAL)
SEE ALSO COMPUTER AND BIOMATHEMATICAL SCIENCES
STUDY SECTION
SEE ALSO MODELS, MATHEMATICAL
** POlHL-07896-15 0009 Environmental biomedical research
program - Decompression sickness and computation of safe
diving tables (human, animals)
** POlHL-08899-14 0073 Tolerance to respiratory gases in
health and disease ■ Biophysical mechanisms involved in
isobaric gas counterditfusion syndrome
** POlHL-08899-14 0074 Tolerance to respiratory gases in
health and disease ■ Biomathematical analysis of isobaric
gas exchange and bubble formation
MAT
POIHI 08899 14 0089 Tolerance to leipiraloiy Ba-.e-. in
health and disease Oerompreiiion by applicalion-, ol
optimal control theory
POIHI 11310 12 9003 Mechanumj o( cirdiovaiculit
disease Core support biophysical sciences
ROlHt 12494 10 Continuum mechanics in biophyiici
(human, animals)
POIHL 14388 07 0183 Regulation ol the circulation in
pathological stales Vasopressin in cardiovascular
regulation (dogs, rats)
** POIHL 17731 04 0002 Physiological basis of pulmonary
disease Biomechanics of the lung (frogs, cats)
POIHL 17813 04 0007 Lung disease and the oxygenation
of blood and tissue Studies on the function of myoglobin
(dogs)
POIHL 1820804 0006 Center for the study ot blood cell
rheology Analysis of flow in arterioles and capillaries
(human)
ROIHL 1896803 Computer technology for transaxial
tomography
** POIHL 20552 02 9002 The development and regression ol
cardiac hypertrophy Core B -Biomathematics
•* POlHL-20993-02 0009 Population dynamics of arterial
cells in atherogenesis Mathematical biology Core
R01HL2176401 Ultramicroanalysis of prostaglandins and
related compounds (rats)
** ROlHL-22963-01 Symbolic logic analysis of congenital
heart disease (human)
MATHEMATICS, STATISTICS (INCLUDING
BIOMETRY)
SEE ALSO NEOPUSTIC DISEASE EPIDEMIOLOGY-STATISTICS
SEE ALSO POPULATION STUDIES HUMAN
SEE ALSO PSYCHOMETRICS
SEE ALSO STATISTICAL SERVICE AND CENTERS
*• N01HB-72982-03 Statistical coordinating center for sickle
cell disease
ROlHL-03429-18 Central nervous system and coronary
heart disease (human)
ROlHL-04697-17 International heart disease epidemiology
(human)
POlHL-1 1310-12 9003 Mechanisms of cardiovascular
disease ■ Core support-biophysical sciences
** P50HL-14 136-07 9001 Pulmonary SCOR-Airvrays
obstructive diseases - Biometrics core
** P50HL-14138-05 0014 Center for research on
atherosclerosis ■ Core biostatistics laboratory
** P50HL-14212-07 0017 Correlated studies of pulmonary
fibrosis - Biometry core
P50HL-14218-07 0011 Pulmonary SCOR -Newborn lung
center ■ Administrative and computer core
** POlHL-14388-07 9004 Regulation of the circulation in
pathological states - Core biostatistics unit
POlHL-14414-07 9002 Environmental influences on
cardiorespiratory and cellular functions - Core-Computer
facility
** P50HL-15092-07 0013 Immune and fibrotic response to
occupational environments ■ Epidemiology core resource
R01HL15174-06 CV disease epidemiology-Second
generation studies (human)
ROlHL-15191-07 Multiparameter methods for
cardiovascular research
ROlHL-16908-04 Myocardial function, risk factors and
future CHD (men)
ROlHL-16909-04 Myocardial function, risk factors and
future CHD (men)
P50HL-17646-04 0002 Study of ischemic heart disease -
Core data management
P50HL-17646-04 0006 Study of ischemic heart disease -
Mathematical models for predicting infarct size using CPK
and other markers
** P50HL-17648-04 0032 Study of ischemic heart disease -
Data management -Statistics and data files
P50HL-17667-04 0030 Study of ischemic heart disease -
Computerized clinical data acquisition and processing
** P50HL-1 7667-04 0041 Study of ischemic heart disease ■
Biophysical sciences core -Data collection and retrieval
P50HL-17667-04 0044 Study of ischemic heart disease -
Core-Data management and analysis
P50HL-17682-04 0009 Study of ischemic heart disease -
Computer core unit
** POlHL-17731-04 0012 Physiological basis of pulmonary
disease - Statistics and computing-Core
** POlHL-18575-03 0013 Mechanisms of vascular changes
in hypertension Biostatistical core
P50HL-19362-02 0017 A/S SCOR -Atherosclerosis in
nonhuman primates - Core laboratory-Data management,
statistical analysis
ROlHL-19567-03 Impact of emotion on coronary arteries
(human)
ROlHL-19864-03 0002 Blood pressure of children and
young adults - Data epidemiology center
ROlHL-20637-02 Recovery after heart surgery-Bio-
behavioral factors (human)
ROlHL-21527-01 Prospective study of bundle branch block
(human)
** POlHL-2 1584-02 9002 Respiratory mechanics in normal
and abnormal states Computational and statistical core
facility
NOlHR-72901-02 Study of intermittent positive pressure
breathing (data center)
NOlHV-32973-12 Coordinating center for collaborative
studies on coronary artery surgery
(contd)
*Excludes routine methodology OR covers only general projects which preclude
**0rjented significantly to above subject.
indexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
MAX
334
NOlHV-72940-02
(human)
Therapy to protect ischemic myocardium
MEM
Synthesis of therapeutically important
MATURE ANIMAL
SEE AGE (ANIMAL), MATURE (ADULT)
MEASLES VIRUS
SEE VIRUSES, MYXOVIRUSES, MEASLES VIRUS
MEAT SUBSTITUTES
SEE FOOD, MEAT SUBSTITUTES
MECAMYLAMINE
SEE NORBORNANES, MECAMYUMINE
MECHANICAL PRESSURE
SEE PHYSICAL PROPERTIES, MECHANICAL PRESSURE
MECHANORECEPTORS
SEE SENSE ORGANS, MECHANORECEPTORS
MECHLORETHAMINE
SEE HALOALKYLAMINES, MECHLORETHAMINE
MECHOLYL
SEE CHOLINE, METHACHOLINE
MEDIASTINUM
SEE BODY CAVITIES, MEDIASTINUM
MEDICAID, MEDI-CAL, TITLE 19
SEE HEALTH ECONOMICS, HEALTH CARE COSTS-FINANCING
MEDICAL INDIGENCY
MEDICAL ASSISTANCE PROGRAMS
SEE HEALTH ECONOMICS, HEALTH CARE COSTS-FINANCING
MEDICAL INDIGENCY
MEDICAL AUDIT
SEE HEALTH CARE QUALITY
MEDICAL CARE COSTS-FINANCING
SEE HEALTH ECONOMICS, HEALTH CARE COSTS-FINANCING
MEDICAL ECONOMICS
SEE HEALTH ECONOMICS
MEDICAL EDUCATION
SEE EDUCATION, HEALTH OCCUPATIONS, MEDICAL
MEDICAL EQUIPMENT SAFETY
SEE BIOMEDICAL ENGINEERING, MEDICAL EQUIPMENT
SAFETY
MEDICAL FACILITIES UTILIZATION
SEE HEALTH CARE (SERVICESXRESOURCES) UTILIZATION
MEDICAL INDIGENCY
SEE HEALTH ECONOMICS, HEALTH CARE COSTS-FINANCING
MEDICAL INDIGENCY
MEDICAL INSURANCE
SEE HEALTH INSURANCE
MEDICAL PERSONNEL PERFORMANCE
SEE HEALTH SCIENCES PROFESSIONS, HEALTH PERSONNEL
PERFORMANCE
MEDICAL PERSONNEL SUPPORTIVE
SEE HEALTH SCIENCES PROFESSIONS, HEALTH (CARE)
PERSONNEL ALLIED
MEDICAL RECORDS
SEE HEALTH RECORDS
MEDICAL RESEARCH
SEE HEALTH SCIENCES RESEARCH (GENERAL)*
MEDICAL SERVICES
SEE HEALTH CARE SERVICES (GENERAL)
MEDICAL STUDENTS
SEE EDUCATION, HEALTH OCCUPATIONS, MEDICAL
MEDICINAL CHEMISTRY STUDY SECTION
SEE ALSO BIOANALYTICAL AND METALLOBIOCHEMISTRY
STUDY SECTION
** ROlHL-12971-15 Reactions of alkoloids and their analogs
'* ROlHL-13581-ir Reactions of oxygen with heme proteins
** ROlHL-13587-06 Synthesis of renin inhibitors and analog
phosphatides (rats)
** ROlHL-16471-05 Cardioactive alloyohimbines and related
indole alkaloids
** ROlHL-16524-02 Selective inhibitors of prostaglandin
biosynthesis (dogs)
" ROlHL-17341-03 Practical total synthesis of
prostaglandins
ROlHL-17896-03
R01HL-I7897-03
antagonists
ROlHL-17921-04
vessels and lung
ROlHL-1811804
ROlHL-1906603
Dehydropeptide renin substrates
Synthesis of alpha and beta adrenergic
Peroxy radicals to prostaglandins in
Total synthesis of cardiac aglycones
Synthesis and evaluation of
prostaglandin metabolites (guinea pigs)
ROIHL 19514-03 Proteinase inhibitor model v»ith clinical
potential
R01HL19538-03 Synthesis of potential antihypertensive
agents
ROlHL-20579-02
alkaloids
ROlHL-20751-01 High speed liquid chromatography of
hemoglobins (human)
ROlHL-20996-02 Structural and reactivity of iron and
Immunologic mechanisms in
Diabetic vascular disease (human.
Polyether ionophores-Synthesis of X537A
Heme group protein interactions in
Blood compatible benzamidine containing
cobalt complexes
** ROlHL-21367-02
and analogs
** ROlHL-21461-01
hemoproteins
** ROlHL-21769-01
polymers
" ROlHL-222 19-01 Prostacyclin and peroxides in blood and
membrane disease
ROIHL 22566-01 Mesoionic purinones as
phosphodiesterase inhibitors
** ROlHL-226 12-01 Stabilized prostacyclins to treat vascular
disease
** ROlHL-22778-01 Total synthesis of natural cardiotonic
ionophores
MEDICINAL PLANTS
SEE PLANTS EXTRACTS, MEDICINAL PLANTS
MEDICINE
SEE ANIMALS, VETERINARY MEDICINE
SEE BEHAVIORAL MEDICINE
SEE ENVIRONMENT, EXTRATERRESTRIAL, SUPRATERRESTRIAL
SEE GENERAL MEDICINE STUDY SECTION
SEE OCCUPATIONAL HEALTH, INDUSTRIAL MEDICINE
MEDICINE, LEGAL
SEE HEALTH SOCIAL CONTROL
MEDITATION
SEE PSYCHIC ACTIVITY LEVEL, TROPHOTROPIC STATE,
MEDITATION
MEDROXYPROGESTERONE ACETATE
SEE PROGESTERONE ANALOGS, MEDROXYPROGESTERONE
ACETATE
MEDULLA OBLONGATA
SEE BRAIN. MEDULLA OBLONGATA
MEETINGS CONFERENCES SYMPOSIA
SEE INFORMATION DISSEMINATION, MEETINGS CONFERENCES
SYMPOSIA
MEGAKARYOCYTE TYPING
SEE BLOOD PUTELET TYPING
MEGAKARYOCYTES
SEE BLOOD AND RE SYSTEM, MEGAKARYOCYTES
MEGALOBLASTIC ANEMIA
SEE BLOOD AND RE DISORDERS, ANEMIA MEGALOBLASTIC
MEGAVITAMIN THERAPY
SEE NUTRITION, DIET THERAPEUTIC, VITAMIN THERAPY (ALL
ROUTES OF ADMINISTRATION)
MELANOIDIN REACTION
SEE CHEMICAL REACTIONS, BROWNING REACTION
MEMBRANE
SEE ALSO CELL COMPONENTS, CELL MEMBRANE
SEE ALSO CELL COMPONENTS, CELL WALL
SEE ALSO CELL COMPONENTS, MITOCHONDRIAL MEMBRANE
SEE ALSO MEMBRANE SURFACE (BIOLOGICAL) ACTIVITY
(GENERAL)
SEE ALSO MOLECULAR FILMS
SEE ALSO PROTEINS, MEMBRANE PROTEINS
SEE ALSO TISSUE, EPITHELIUM
P01HL-08899-14 0075 Tolerance to respiratory gases in
health and disease - Gas diffusion rates and bubble
formation across membranes (animals)
ROlHL-201 14-02 Collagen-platelet interaction and human
aorta collagen (human)
** ROlHL-222 19-01 Prostacyclin and peroxides in blood and
membrane disease
MEMBRANE, BASEMENT MEMBRANE
** R01HL-01803-23 0016 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Synthesis of basement membrane
collagen by endothelial cells (human)
** P01HL-031 74-23 0007 Mechanisms of acute vascular
reaction to injury - Healing of injured myocardium-Basal
lamina scaffold (human, rats, dogs)
** PaiHL-0628518 0149 Cardiovascular-respiratory
physiology and biochemistry - Microangiopathy in
prediabetic and diabetic subjects (human)
** POlHL-06285-18 0150 Cardiovascular-respiratory
physiology and biochemistry - Basement membrane width
in non-diabetic hyperglycemia
** POlHL-06285-18 0151 Cardiovascular-respiratory
physiology and biochemistry - Microangiopathy in diabetic
and glucose intolerant children
** POlHL-06285-18 0152 Cardiovascular-respiratory
physiology and biochemistry - Diabetic microangiopathy by
organ and tissue culture (human)
POlHL-063 14-17 0063 Immunologic mechanisms in
cardiovascular disease - Glomerular cells in tissue culture
(human)
Electro-optical dyes as probes of heart
POlHL-06314-17 0064
cardiovascular disease
rats, mice)
POlHL-11310-12 0106 Mechanisms of cardiovascular
disease - Biochemical characterization of the collagens in
vascular tissue (catte)
ROlHL-13632-08 Vascular changes in diabetes mellitus
(human)
** ROlHL-13694-08 Capillary basement membrane in
cardiovascular disease (human, rats)
** POlHL-16387-04 0004 The blood vessel and
thrombogenesis - Analysis of vascular basement membrane
by enzymatic methods (human)
ROIHL- 16490-04 Structural basis of nephron filtration
(rats, rabbits)
ROIHL- 17702-04
excitability
ROlHL-17973-04 Cultured aortic endothelial cells (human,
cattle, dogs, swine)
** ROlHL-18714-04 Cardiovascular matrix -Morphogenesis
and maturation (human, chick embryo, mammal)
POlHL-18827-02 0001 Platelet vessel wall interactions in
thrombogenesis ■ Role of endothelial cells in the production
of thrombi (human, cattle)
P50HL-18828-03 0002 Specialized center of research in
thrombosis - Endothelial cell biology (human, guinea pig)
ROlHL-19316-03 Study of glomerular permeability (fish,
turtle, frog, chordates, Crustacea)
R01HL19731-03 Collagen in interstitial fibrosis of lung
(human)
** ROIHL 20500-02 Diabetic human brain microvascular
basement membrane (human)
ROlHL-20539-03 Blood glucose, hemoglobin Ale, and
diabetic vascular disease (human)
ROlHL-20635-03 Factors in lung development (rat and
chick embryo)
R23HL-21396-02 Isolation, growth and metabolism of type
1 pneumocytes (rabbits)
ROlHL-22583-02 Ultrastructural study of endothelium in
thrombosis (human)
MEMBRANE, BRUSH BORDER MEMBRANES
ROlHL-09125-14 Ultrastructural cytochemistry (human,
Control of cholesterol metabolism -Bile
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level
•'Onented significantly to above subject.
M Grant has subprajects describing specific research aspects
See Appendix for investigator's name and grant number.
chick)
ROlHL-09610-14
acid transport
ROlHL-16320-05 Vasoactive peptides which stimulate
smooth muscles (rats, human)
R01HL-22172-01 Hypotension, renal ischemia and effect of
mannitol (dogs, rats)
MEMBRANE, ERYTHROCYTE GHOST AND
MEMBRANE
NOlHB-62962-02 Red cell distributions in cyanate-freated
blood (human, sheep)
** ROlHL-01974-24 Ion-pump in the erythrocyte (rabbits,
guinea pigs)
ROlHL-02063-23 Biochemistry and function of lipids and
cell membranes (human, yeast, animals)
POlHL-06835-17 0018 Cardiovascular disease - Fatty
acid concentration (rats)
POlHL-06835-17 0019 Cardiovascular disease - Fatty
acid distribution (rats)
ROlHL-07449-17 Formation and survival of red blood cells
(human)
ROlHL-07652-14 Destruction of red blood cells in
hemolytic anemias (human, guinea pigs)
ROlHL-08893-14 Structure and function of membrane
proteins (human)
** ROlHL-09906-13 0018 Membrane transport processes in
red blood cells - Rapid photolytic release of ATP from a
protected analog-Na-K pump of RBC ghosts
ROlHL-10383-12 Physical-chemical studies of hemoglobins
and erythrocyte (human)
R01HL11153-12 Quantitation of flow and solute flux in
microvessels (cats, rats)
ROlHL-11154-12 Blood group antigens and antibodies
(human)
POlHL-12157-11 0033 Functions and mechanisms of cell
membrane ion transport - Immunology aspects of active
Na-K transport in sheep red cell (also human, mice)
** POlHL-12157-11 0051 Functions and mechanisms of cell
membrane ion transport ■ Electron transport in the red cell
membrane (human, guinea pigs)
" ROlHL-12839-09 Flow, transport and membrane
phenomena in blood (human)
ROlHL-12974-10 Tracer kinetics, flows and masses In
body organs (human, dogs)
** ROlHL-12994-09 The Rh complex of red cells (human)
ROlHL-13029-09 Metabolic regulation of sugar transport
(pigeons, rats)
" ROlHL-13256-08 Amino acid transport by red cell
membranes (pigeons)
ROlHL-13567-06 Ion transport across cell membranes
(human)
ROlHL-13619-09 Microsomal electron transport in liver
and heart (human, mammals)
POlHL-14414-07 0016 Environmental influences on
cardiorespiratory and cellular functions - Effects of
pressure on membrane and cellular function (human,
rabbits)
* ROlHL-14820-07 Factors affecting physiology of biological
membranes (human)
(contd)
MEM
P60HI 151!)7 07 0009 Comptehensive ceiilei lot Jickle
call distisa Rtd call membtane altarations during
sickling (human)
P60HL 15157 07 0018 Comprebensiva center lor sickle
call disease Red blood cell membrane physiology in sickle
cell anemia (human)
P60HL 15162 07 0017 Compiehensiwe sickle cell center
Hemoglobin, erythrocytes and sickle cell anemia (human,
rabbit)
P60HL 15162 07 0019 Comprehensive sickle cell center
R6C Blood rheology in sickle cell anemia and related
disorders (human, animal)
P60HL 15162 07 0020 Comprehensive sickle cell center
Biophysical studies ol normal and sickle red cells (human)
P60HI 1516905 0018 Support tor center tor sickle cell
disease - Studies on sickle cell disease (human, rats,
dogs)
P01HL15194 07 0009 Pathophysiology o(
cardiopulmonary dysfunction Kinetics of gas exchange-
Diffusion and erythrocytes reaction rates (human, dogs)
' ROIHL 1379306 Molecular aspects ol erythrocyte
membrane resealing (human)
P60HL 1600505 0020 Comprehensive sickle cell center
Studies of the immunologic defect in sickle cell anemia
(human)
• P60HL1600806 0018 Wayne State University
comprehensive sickle cell center Hemoglobin S and RBC
membranes -Pathogenesis of irreversibly sickled cells
R01HL16059-06 Structure and function of serum
lipoproteins (cattle, human)
R01HL1609305 Functional properties of hemoglobin and
Investigation of hemoglobin S properties
erythrocytes
ROIHL 1637504
(human)
R01HL1642108 Determinants of RBC deformability and
capillary flow (human, mice)
R01HL16660-06 Phospholipidcholesterol and
phospholipid'Protein interactions
ROlHL-16711-05 RBC and endothelial membrane material
characteristics (human)
P01HL16833-04 Hemoglobin and red cell system in
hemoglobinopathies
Hemoglobin and red cell system in
Membrane associated phenomena in
POlHL-16833-04 0008
hemoglobinopathies
SS disease
P01HL16833-04 0011
hemoglobinopathies
Hemoglobii. and red cell system in
Relationship between hemoglobin and
RBC membrane in sickling cells (human, rats)
POlHL-16833-04 0014 Hemoglobin and red cell system in
hemoglobinopathies ■ Erythrocyte membrane damage in Hb
SS disease (human)
P01HL1685104 Human red cell membrane in health and
disease
POlHL-16851-04 0001 Human red cell membrane in
health and disease ■ Rheology of erythrocyte membrane
(human, amphiuma)
POlHL-16851-04 0003 Human red cell membrane in
health and disease • Modeling membrane mechanics and
blood rheology
POlHL-16851-04 0005 Human red cell membrane in
health and disease ■ Relation of hemoglobin species to
membrane properties (human)
POlHL-16851-04 0006 Human red cell membrane in
health and disease ■ Hexose transport and erythrocyte
membrane proteins (human)
POlHL-16851-04 0008 Human red cell membrane in
health and disease - Force balance in red cell interactions
(human)
ROlHL-17411-04 Molecular studies of red blood cell
spectrin (human)
ROlHL-17462-03 Role of glycosphingolipids in platelet
aggregation (rats, human, dogs)
R01HL17463-03 Composition and structure of plasma
lipoproteins (human, rabbits)
ROlHL-17567-03 Lipoprotein-cytolytic toxin interaction
(Staphylococcus aureus, mammals, human)
ROlHL-17576-04 Role of sphingomyelin in biomembranes
and bilayers (rats, other mammals)
R01HL17878-04 Structural studies of the human
erythrocyte membrane
ROlHL-1796704 Limiting factors in oxygen uptake in the
lung
R01HL18048-04 Dynamics of artificial and biological
membranes (human)
R01HL18163-04 Red cell membrane effects due to
oxidizing agents
POIHL- 18208-04 0001 Center for the study of blood cell
rheology - Physiological basis of reversible erythrocyte
shape change (human, firefly)
POIHL- 18208-04 0005 Center for the study of blood cell
rheology RBC deformability and capillary flow
interrelations (human, mice)
POlHL-18208-04 0006 Center for the study of blood cell
rheology - Analysis of flow in arterioles and capillaries
(human)
' POlHL-18208-04 0007 Center for the study of blood cell
rheology - RBC membrane protein (human)
• ROlHL-18551-03 Spectrin, actin, lipid and red cell
membrane structure
POlHL-18577-03 0003 Lipoproteins-Ccll surface
interactions - Mechanism of lipid exchange in lipoproteins
and cell membranes
335
ROIHL 1866003 Neurotransmitter receptors in human
erythrocytes
ROIHL 18737 03 Human erythrocyte membrane structure
P50HI 1882803 0004 Specialized center of research in
thrombosis Membrane changes in platelet physiology Role
of complement (mice, human)
ROIHL 19068 03 Changes in membrane properties during
erythropoiesis (chick embryo)
POIHL 19737 02 0004 Cellular and molecular aspects of
respiratory physiology Rapid reactions and erythrocyte
exchanges of blood during respiratory transport
POIHL 1973702 0010 Cellular and molecular aspects of
respiratory physiology EHects of pulsatile flow and volume
on capillary exchanges (dogs, rats)
ROIHL 19933 02 Membrane and red cell dysfunction in
hemolytic anemia (human)
• ROlHL-2024102 Shear and area moduli for abnormal red
cell membranes (human)
ROIHL 2030102 Genetics of glycosyltransferases m
human blood
• ROIHL 20303-03 Cholesterol distribution m erythrocyte
membrane (human, animals)
ROlHL-20365 03
ROIHL 20725-02
transport
ROIHL 20750-01
ROIHL 20859-02
ROlHL-20882-02
Molecular mechanisms of anion transport
Mechanisms and cellular functions of ion
Studies in sickle cell disease (human)
Beta adrenergic catecholamine receptor
Interactions of plasma lipoproteins with
erythrocytes (Rhesus, human)
P60HL 20985-01 0004 Northern California sickle cell
center - Characterization of irreversibly sickled cells
(human)
P60HL-20985-01 0006 Northern California sickle cell
center Antisickling properties of imidoesters (human, rats)
POIHL 210 16-02 0005 Sickle cell anemia and other
hemoglobinopathies - Ligand kinetics in normal and Hb S
containing erythrocytes (human)
POlHL-21016-02 0007 Sickle cell anemia and other
hemoglobinopathies - Cellular determinants of red cell
sickling
POlHL-21016-02 0017
hemoglobinopathies
Sickle cell anemia and other
The hereditary clinic core
R23HL-21051-02 Adrenergic receptors and the adenylate
cyclase system (frog RBC)
ROlHL-21096-02 Sickle cell crisis-Role of the erythrocyte
membrane (human)
R23HL-21328-02 The I blood group antigen of human
erythrocyte membrane
ROlHL-21404-01 Raman spectroscopy of erythrocyte and
model membranes (human)
ROlHL-21525-02 Effect of cations, anions and water upon
blood vessels (dogs, rats)
ROlHL-22233-01
elastic property
ROlHL-22432-01
membranes
ROlHL-226 50-01
production (human, rats, mice)
ROlHL-22671-01
red cells
Characterization of bio-materials by
Molecular studies of human erythrocyte
Regulatory mechanisms of erythropoietin
1, rats, mice)
Removal of senescent and stored human
Membrane biochemistry of RH antigens
Erythocyte membrane sulfhydrls and Rh
" ROlHL-23108-01
(human)
** ROlHL-24021-02
activity (human)
MEMBRANE, MEMBRANE (BIOLOGICAL)
STRUCTURE
SEE ALSO BIOLOGICAL TRANSPORT, MEMBRANE MODELS
** ROlHL-02063-23 Biochemistry and function of lipids and
cell membranes (human, yeast, animals)
R01HL-02477-23 Biosynthesis and function of lipids
(microorganisms, rats)
** POlHL-06285-18 0211 Cardiovascular-respiratory
physiology and biochemistry - Purple membrane of
Halobacteria
POlHL-06285-18 0212 Cardiovascular-respiratory
physiology and biochemistry - Membrane structure and
function -Gap junction (bovine)
POlHL-06285-18 0213 Cardiovascular-respiratory
physiology and biochemistry - Membrane structure and
function-Gas vacuole membrane (Halobacterium)
POlHL-06285-18 0214 Cardiovascular-respiratory
physiology and biochemistry - Membrane structure and
function-EM of macromolecules
ROlHL-07449-17 Formation and survival of red blood cells
(human)
POlHL-082 14-15 0025 Chemical and biological properties
of lipids - Biosynthesis and biological functions of
plasmalogen (cattle)
P01HL-082 14-15 0040 Chemical and biological properties
of lipids - Nuclear magnetic resonance studies of lipids
** ROlHL-08893-14
proteins (human)
ROlHL-10018-11
culture (rats)
** R01HL-10940-13
ROlHL-11154-12
(human)
** POlHL-1 13 10-12 0097 Mechanisms of cardiovascular
disease ■ Structural-functional relationships of neuronal
differential alloantigens (mice)
** POlHL-11310-12 0102 Mechanisms of cardiovascular
disease - Cardiac membrane and ion mobility (dogs)
Structure and function of membrane
Effect of aging on beating heart cells in
Lipid transport (rabbits, cattle, chickens)
Blood group antigens and antibodies
MIM
POIHI 11310 1? 0105 Mechaniimi of cardiovatcular
disea^o Bio\ynlhe»i5 of mammalian glytoproleins
(rabbits)
POIHI 12/38 10 0135 Physiologic pharmacology and its
chnical applications Myocardial cells in tissue culture
(rats, chick embryo)
ROIHL 12745 10 En/ymes and inhibitors of cholesterol
biosynthesis (rats, human, swine)
ROIHL 1276009 Surface studies ol membrane lipids and
proteins
ROIHL 12839 09 flow, transport and membrane
phenomena in blood (human)
ROIHL 1286909 Arterial metabolism, diabetes and
atherogenesis (rats, rabbits)
ROIHL 1325608 Ammo acid transport by red cell
membranes (pigeons)
ROIHL 1333609 Biochemistry and physiology of human
platelets
' ROIHL 14111-07 Cholesteryl esters in membranes and
atherosclerosis (iiuiMO", .« -itj
P50HL 14230 07 0092 A/S SCOR Lipids, atherosclerosis
and thrombosis Tissue lipids Cell culture studies
(human)
' ROIHL 14697-07 Role of platelet membranes in
hemostasis (human)
' ROlHL-14781 08 Lipid deposition in mammalian cells
(mice)
R01HL1482007 Factors affecting physiology of biological
membranes (human)
* P60HL-15157-07 0009 Comprehensive center for sickle
cell disease Red cell membrane alterations during
sickling (human)
* P60HL 1515707 0018 Comprehensive center for sickle
cell disease - Red blood cell membrane physiology in sickle
cell anemia (human)
P60HL15162-07 0017 Comprehensive sickle cell center -
Hemoglobin, erythrocytes and sickle cell anemia (human,
rabbit)
* P60HL-15162-07 0020 Comprehensive sickle cell center -
Biophysical studies of normal and sickle red cells (human)
ROlHL-15335-06 The nature of the collagen-platelet
interaction (animals)
ROlHL-15567-05 Cardiovascular phosphoinositide
metabolism (rats)
R01HL-15728-06 The carbohydrate of the blood-clotting
glycoproteins (mammals)
ROlHL-15793-06 Molecular aspects of erythrocyte
membrane resealing (human)
P60HL-16008-06 0018 Wayne State University
comprehensive sickle cell center ■ Hemoglobin S and RBC
membranes-Pathogenesis of irreversibly sickled cells
ROlHL-16059-06 Structure and function of scrum
lipoproteins (cattle, human)
'* ROlHL-16101-05 Protein-lipid interaction (bacteria,
models)
ROlHL-16355-05 Reactions of thrombin and collagen with
platelets (human)
ROlHL-16421-08 Determinants of RBC deformability and
capillary flow (human, mice)
ROlHL-16474-05
membranes)
ROlHL-16646-05
(human)
•* ROIHL- 15660-06 Phospholipid-cholesterol and
phospholipid-protein interactions
** ROlHL-16711-05 RBC and endothelial membrane material
characteristics (human)
ROlHL-16938-05 Effect of physical forces on blood (dogs,
human)
** ROlHL-17411-04 Molecular studies of red blood cell
spectrin (human)
** ROlHL-17576-04 Role of sphingomyelin in biomembranes
and bilayers (rats, other mammals)
ROlHL-17596-03 Leukocyte-endothelial interactions (rats)
** ROlHL-17878-04 Structural studies of the human
erythrocyte membrane
** ROlHL-17930-03 Platelet membrane function-Assessment
and application (animals)
ROlHL-17973-04 Cultured aortic endothelial cells (human.
cattle, dogs, swine)
ROlHL-18012-04 Cellular defects in nocturnal
hemoglobinuria (human)
ROlHL-18030-04 The role of contractile proteins in
platelets (human, rabbits)
ROlHL-18038-03 Structure and function of heart
mitochondria (cattle)
** R01HL-18048-D4 Dynamics of artificial and biological
membranes (human)
M POlHL-18208-04 Center for the study ol blood cell
rheology
POlHL-18208-04 0005 Center for the study of blood cell
rheology - RBC deformability and capillary flow
interrelations (human, mice)
POlHL-18208-04 0007 Center for the study of blood cell
rheology - RBC membrane protein (human)
** ROlHL-18249-04 Isolation and identification of platelet
membrane (human)
ROlHL-18255-04 Lipid-protein interactions and calcium
transport (models)
** ROlHL-18551-03 Spectrin, actin, lipid and red cell
membrane structure
(contd)
Antibiotic-ion interactions (model
Pathobiology of thromboembolic disorders
•Excludes routine methodology OR covers only general projects which preclude
**Onented significantly to above subject.
indexing at the specific level.
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
MEM
ROlHL-18623-12 Physical chemistry of biologically active
lipids (bacteria, plant, cattle, human)
' R01HL18660-03 Neurotransmitter receptors in human
erythrocytes
' R01HL18737-03 Human erythrocyte membrane structure
■ ROlHL-18746-02 Chemical studies on proteolipid
apoproteins (cattle)
ROlHL-19011-03 Smooth muscle cell membrane
glycoprotein biosynthesis (cattle)
ROlHL-19068-03 Changes in membrane properties during
erythropoiesis (chick embryo)
ROlHL-1907203 Modification of tissue injury in
myocardial infarction (dogs, human)
ROlHL-1914803 Myocardial organelle lipid structure and
function (dog, rat)
ROlHL-19316-03 Study of glomerular permeability (fish,
turtle, frog, chordates, Crustacea)
ROlHL-1939203 Spectroscopic studies of respiratory
metalloproteins
ROlHL-1993302 Membrane and red cell dysfunction in
hemolytic anemia (human)
ROlHL-1993602 Unsaturated fatty acid biosynthesis in
the aorta (rats)
ROlHL-2014002 Glycoproteins of platelet membrane and
platelet function (human)
ROlHL-20241-02 Shear and area moduli for abnormal red
cell membranes (human)
ROlHL-20303-03 Cholesterol distribution in erythrocyte
membrane (human, animals)
ROlHL-2035002 Crystal structure of lipids-Cholesterol
ROlHL-2036503 Molecular mechanisms of anion transport
ROlHL-20500-02 Diabetic human brain microvascular
basement membrane (human)
ROlHL-20882-02 Interactions of plasma lipoproteins with
erythrocytes (Rhesus, human)
ROlHL-21096-02 Sickle cell crisis -Role of the erythrocyte
membrane (human)
R23HL-21328-02 The I blood group antigen of human
erythrocyte membrane
ROlHL-21404-01 Raman spectroscopy of erythrocyte and
model membranes (human)
ROlHL-21469-01 Active transport and effect of CAOO in
sickle cell (human)
R23HL-21490-02 Studies of enzymes in human platelet
membranes
R01HL-2I845-01
function
R23HL-21894-01
(cattle)
ROlHL-21988-01
chemotaxis
ROlHL-22050-01
ROlHL-22 174-01
ROlHL-22327-01
skin (swine)
336
Transport of arterial blood gases through
Human red cell membrane-Structure and
Pulmonary angiotensin converting enzyme
Biochemistry of human platelet
Membrane biochemistry of RH antigens
Organization of succinic oxidase in heart
Assembly of membranes in heart and
yeast mitochondria
" ROlHL-22432-01 Molecular studies of human erythrocyte
membranes
ROlHL-22502-01 Role of phosphojnositides in human
platelet secretion
ROlHL-22583-02 Ultrastructural study of endothelium in
thrombosis (human)
ROlHL-22771-01 Thrombogenic phospholipid surfaces
(cattle)
R23HL-22839-01 Cellular translation of liposomally-
delivered mRNA (human, mammals)
ROlHL-22951-01 Studies on the affect of vitamin E on
platelets (human, rats)
ROlHL-22981-17 Membrane-associated functions in
microorganisms (bacteria, protozoa)
ROlHL-23013-01 Smooth muscle development in vitro
(chick embryo)
" ROlHL-23108-01
(human)
ROlHL-23142-01 Mechanisms of membrane injury in
myocardial ischemia (dog)
ROlHL-23392-01 Membrane binding and transport of
calcium and potassium ionophores
** ROlHL-23593-01 Mast cell granules-Structure and
secretion (rats)
MEMBRANE, MUCOUS MEMBRANE
SEE ALSO GASTROINTESTINAL SYSTEM, INTESTINES, MUCOSA
" P01HL-06285-I8 0189 Cardiovascular-respiratory
physiology and biochemistry - Mucociliary clearance (cats,
dogs)
•* POlHL-1043613 0016 A multidisciplinary study of
congenital heart disease - Genetic studies of congenital
heart disease (human)
** R23HL-2 II 50-02 Regulation of airway mucous glands and
ion transport (dogs, ascaris)
** ROlHL-22924-01 The airway mucosal barrier (guinea pigs)
MEMBRANE, MULTILAYER MEMBRANES
** POlHL-06285-18 0210 Cardiovascular-respiratory
physiology and biochemistry - Physicochemical and
enzymatic studies of lung surfactant (Halobacterium)
R01HL16093-05 Functional properties of hemoglobin and
erythrocytes
ROlHL-16711-05 RBC and endothelial membrane material
characteristics (human)
P60HL-1 7269-04 0017 National heart and blood vessel
research and demonstration center ■ Cell membrane (dogs,
rabbits)
MEMBRANE, PROSTHETIC MEMBRANES
SEE ALSO RESPIRATORY SYSTEM PROSTHESIS, PROSTHETIC
LUNG
POlHL-063 14-17 0051 Immunologic mechanisms in
cardiovascular disease ■ Conformational studies of
phospholipid membranes and proteins
** R01HL1194510 Synthesis of artificial lung and kidney
systems (sheep, mice, swine)
** ROlHL-1283909 Flow, transport and membrane
phenomena in blood (human)
R01HL15668-06 Extracorporeal respiratory gas exchange-
A new approach (dogs)
R01HL16582-05 Artificial lungs (dogs)
POlHL-1685104 0003 Human red cell membrane in
health and disease ■ Modeling membrane mechanics and
blood rheology
** POlHL-18576-03 0003 Thrombosis research program
project - Biocompatible materials
ROlHL-20073-02 Blood compatible materials by fluid
perfusion (human, dogs)
ROlHL-2149802 Pathophysiology of edema (rats, cats)
ROlHL-22661-01 Chronic total cardiopulhonary mechanical
substitution (sheep)
ROlHL-23899-01 Flow and flexing at blood/biomaterial
interfaces
NOlHV-3291912 Material development and testing
heparinization processes
MEMBRANE (BIOLOGICAL) STRUCTURE
SEE MEMBRANE, MEMBRANE (BIOLOGICAL) STRUCTURE
MEMBRANE MODELS
SEE BIOLOGICAL TRANSPORT, MEMBRANE MODELS
MEMBRANE OXYGENATORS, BLOOD
SEE CARDIOVASCULAR SURGERY, CIRCULATORY ASSIST,
BLOOD OXYGENATORS
MEMBRANE PERMEABILITY AND TRANSPORT
SEE BIOLOGICAL TRANSPORT, MEMBRANE PERMEABILITY
AND TRANSPORT
MEMBRANE POTENTIALS
SEE ELECTROPOTENTIALS, MEMBRANE POTENTIALS
MEMBRANE PROTEINS
SEE PROTEINS, MEMBRANE PROTEINS
MEMBRANE SURFACE (BIOLOGICAL) ACTIVITY
(GENERAL)
SEE ALSO CELL ADHESION
SEE ALSO CELL-CELL INTERACTION, CELL AGGREGATION
SEE ALSO IMMUNOLOGY, ANTIGENS, SURFACE ANTIGENS
(GENERAL)
** POlHL-031 74-23 0013 Mechanisms of acute vascular
reaction to injury - Surface morphology of the aorta in
normal and injured states (rats, rabbits)
" ROlHL-039 19-20 The cell suface of streptococci (rats,
human)
ROlHL-05062-18 Lipid metabolism in cultured cells
(human, rats, rabbits)
POlHL-06285-18 0209 Cardiovascular-respiratory
physiology and biochemistry - Metabolic studies of isolated
lung cells (human, animals)
POlHL-06285-18 0210 Cardiovascular-respiratory
physiology and biochemistry - Physicochemical and
enzymatic studies of lung surfactant (Halobacterium)
POlHL-06285-18 0211 Cardiovascular-respiratory
physiology and biochemistry - Purple membrane of
Halobacteria
POlHL-06285-18 0213 Cardiovascular-respiratory
physiology and biochemistry - Membrane structure and
function-Gas vacuole membrane (Halobacterium)
POlHL-09011-15 0001 A research and resource program
in blood ■ Genetic markers of human blood and gene
mapping (human)
** ROlHL-09125-14 Ultrastructural cytochemistry (human,
chick)
ROlHL-09739-13
ROlHL-11154-12
(human)
** POlHL-1 13 10-12 0099 Mechanisms of cardiovascular
disease - Carbohydrate chemistry of thyl and related
synaptosomal proteins
POlHL-1 1351-12 0002 Cellular and molecular
mechanisms of myocardial function - Effects of hypoxia
and ischemia on ionic exchange (rats, rabbits)
** POlHL-1 1351-12 0009 Cellular and molecular
mechanisms of myocardial function - Myocardial membrane
surface coat (rats, rabbits)
** R01HL12760-09 Surface studies of membrane lipids and
proteins
ROlHL-12994-09 The Rh complex of red cells (human)
ROlHL-13831-08 Factors regulating embryonic cardiac
morphogenesis (chick, salamandra)
P50HL-142 14-07 0024 Newborn lung center for hyaline
membrane disease - Synthesis and receptors for ACTH in
fetal lung (human)
P50HL-14217-08 0058 Specialized center of research in
thrombosis - Mechanisms of induction and inhibition of
platelet reaction (human, pig)
Biophysical studies of proteins (human)
Blood group antigens and antibodies
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
••Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
MEM
P50HL-I4230-07 0096 A/S SCOR -Lipids, atherosclerosis
and thrombosis - Ultrastructural studies of endothelial cells
(human)
P50HL-14237-07 0002 Support for arteriosclerosis center
- Interactions of lipoprotein particles with vascular surface
(human, rat)
ROlHL-14990-07 Lipid transport in avian species
(chickens)
P60HL-15157-07 0012 Comprehensive center for sickle
cell disease - Sickling and intracellular pH (human)
P60HL-15162-07 0017 Comprehensive sickle cell center ■
Hemoglobin, erythrocytes and sickle cell anemia (human,
rabbit)
* P60HL-1 51 62-07 0020 Comprehensive sickle cell center -
Biophysical studies of normal and sickle red cells (human)
POlHL-15596-05 0014 Coagulation, fibrinolysis,
hemostasis and hepatitis - Von Willebrand factor and
platelet retention in glass bead columns (swine)
ROlHL-1561604 Platelet membrane proteins in
aggregation (human)
ROlHL-15799-04 Effect of anesthetics on myocardial
function (cats)
* ROlHL-16634-13 Regulation of metabolism in fibroblasts
and platelets (human, rabbits, sheep)
R01HL16711-05 RBC and endothelial membrane material
characteristics (human)
ROlHL-16921-05 Synthetic hydrogels as blood tolerable
materials
* P60HL-1 7269-04 0045 National heart and blood vessel
research and demonstration center - Regulation of
lipogenesis in hyperlipoproteinemia (human, tissue culture)
ROlHL-17404-05 Immunologic mechanisms in heart
disease (mice)
ROlHL-17596-03 Leukocyte-endothelial interactions (rats)
POIHL- 178 12-04 0005 Thrombosis and plasma proteins -
In vitro systems of normal platelets, white cells, sera
(human)
ROlHL-18181-04 Surfactant metabolism -Alveolar cells and
lung disease (mice, rabbits)
ROlHL-18219-04 Regulation of cholesterol metabolism
(rats)
ROlHL-18249-04 Isolation and identification of platelet
membrane (human)
ROlHL-18256-01 Optical properties of platelets and
erythrocytes (rabbits, dogs, human)
ROlHL-18284-04 Aging erythrocytes-Biorecognition and
elimination (monkeys)
' ROlHL-18519-03 Albumin, endothelium and
hemocompatibility (human, dog, cattle, rabbit)
' ROlHL-18553-03 Membrane defects in familial
hypercholesteremia (human)
POlHL-18577-03 Lipoproteins -Cell surface interactions
POlHL-18577-03 0001 Lipoproteins-Cell surface
interactions - Structural studies of serum lipoproteins in
man and dogs
POlHL-1857703 0003 Lipoproteins-Cell surface
interactions - Mechanism of lipid exchange in lipoproteins
and cell membranes
ROlHL-18584-03 Effects of physical forces on platelets
(human)
P01HL-18646-03 0009 Studies basic to heart
transplantation - Pathologic aspects of cardiac allograft
rejection (sheep, dogs)
ROlHL-18660-03 Neurotransmitter receptors in human
erythrocytes
P50HL-18828-03 0001 Specialized center of research in
thrombosis • Membrane biology and hemostasis (human)
P50HL-18828-03 0002 Specialized center of research in
thrombosis - Endothelial cell biology (human, guinea pig)
P50HL-18828-03 0008 Specialized center of research in
thrombosis ■ Biochemistry, physiology-Platelets and
subcellular platelet particles (human)
P50HL-18828-03 0009 Specialized center of research in
thrombosis - Platelet formation and megakaryocyte cell
biology (guinea pig, human)
ROlHL-18878-03 Familial hypercholesteremia-Studies of
fibroblasts (human)
ROlHL-19055-03 Platelet function during extracorporeal
perfusion (human, mammals)
ROlHL-19068-03 Changes in membrane properties during
erythropoiesis (chick embryo)
P50HL-19171-02 0008 Pulmonary SCOR-Lung injury by
childhood infections - Host-parasite interaction-Electron
microscopy, radioautography, histochemistry
P50HL19171-02 0009 Pulmonary SCOR-Lung injury by
childhood infections - Host-parasite interaction-Scanning
electron microscopy, freeze-fracture methods
POlHL-19242-02 0002 Study of vascular smooth muscle -
Vascular smooth muscle response to serum lipoproteins
(rats)
ROlHL-19419-03 Cellular interactions with foreign
materials (mammals)
R23HL-19594-01 Tropocollagen and tropoelastin uptake in
lung cells (human)
ROlHL-19725-03 Complement induced pulmonary injury
(dogs, rabbits, sheep)
ROlHL-19779-03 Biochemical basis of oxygen damage to
lung cells (guinea pigs, rats)
ROlHL-19836-03 Kinin inhibitors detected by use of
receptors (cattle)
ROlHL-19996-02 Role of membrane proteins in platelet
function (human, rabbits)
(contd)
337
* ROIHI 20140 02 Glycopioleins ol platelet membiane and
platelet lunclion (human)
ROIHL 20365 03 Molecular mechanisms ot anion tcansport
ROIHL 20711 01 Stiucluie lunction relationships in red
cell NA K pumps (loats)
ROIHL 20787 02 Thromboxanes and prostanlandms
Biochemical pharmacology (rabbits, human)
ROIHL 2089902 Cellular mechanisms ot hemojlobin F
re(ul8tion (human)
" ROIHL 20971 10 Membrane glycoproteins ot platelets and
leukocytes (human)
P60HL-20985 01 0006 Northern California sickle cell
center Antisickling properties of imidoesters (human, rats)
POIHL 2101602 0009 Sickle cell anemia and other
hemoglobinopathies Nitrogen mustards and their potential
use as antisickling agent
ROIHL 2109602 Sickle cell crisis -Role ol the erythrocyte
membrane (human)
ROlHL-21217-01 Ion and Shydroxytryptamine transport by
platelets
ROIHL 21487 01 Molecular characleruation of
Glanimann's thrombasthenia (human)
R23HL 2195001 Endothelial cell mechanisms in vascular
disease (human)
ROlHL-2255501 Structure and function of platelet
activating factor (rabbits, human)
** ROlHL-2277101 Thrombogenic phospholipid surfaces
(cattle)
R23HL-22839-01 Cellular translation of liposomally-
delivered mRNA (human, mammals)
ROlHL-2288301 Lung epithelial cell interactions in vitro
ROIHL 2298301 Studies on the catabolism of plasma
lipoproteins (rats)
ROIHL-2300301 Bulk-surface distribution of cholesteryl
esters
** ROlHL-23161-01 0003 Biology of myocardial ischemia ■
Phosphorylase coupling to myocardial sarcoplasmic
reticulum (dog)
ROlHL-23206-01 Repetitive exercise and cardiac
enlargement (dogs)
ROlHL-23210-01 Biology of normal and hypertrophied
pulmonary vessels (cat. human)
ROlHL-23245-01 Adrenergic receptors in pulmonary
vascular muscle (human, animal)
NOlHV-5290704 Interactions of platelets with collagens
(human, mammals)
MEMBRANE SYNTHESIS AND RECONSTITUTION
ROlHL-02986-21 Zonal renal change with potassium
deficiency (rats, human)
ROlHL-0889314 Structure and function of membrane
proteins (human)
** P01HL11310-12 0102 Mechanisms of cardiovascular
disease - Cardiac membrane and ion mobility (dogs)
R01HL16421-08 Determinants of RBC deformability and
capillary flow (human, mice)
R01HL16507-04 Heart cell interactions and cell junction
biogenesis (mice. rats, rabbits)
POlHL-16607-05 0001 Calcium ion and control of
cardiovascular function ■ Bilayer lipid membranes,
antibiotic probes, and SR function
R01HL174U-04 Molecular studies of red blood cell
spectrin (human)
** ROlHL-18048-04 Dynamics of artificial and biological
membranes (human)
ROlHL-18255-04 Lipidprotein interactions and calcium
transport (models)
** R01HL18553-03 Membrane defects in familial
hypercholesteremia (human)
** ROlHL-19011-03 Smooth muscle cell membrane
glycoprotein biosynthesis (cattle)
ROlHL-19068-03 Changes in membrane properties during
erythropoiesis (chick embryo)
** ROlHL-19933-02 Membrane and red cell dysfunction in
hemolytic anemia (human)
** R01HL-2063503 Factors in lung development (rat and
chick embryo)
** ROlHL-21246-02 Roles of cholesterol and its metabolic
regulation (CHO cell mutants)
ROlHL-21394-02 Pulmonary angiotensin-converling enzyme
(rabbits)
ROlHL-21487-01 Molecular characterization of
Glanzmann's thrombasthenia (human)
ROlHL-21845-01 Human red cell membrane -Structure and
function
ROlHL-22172-01 Hypotension, renal ischemia and effect of
mannitol (dogs, rats)
** ROlHL-22174-01 Assembly of membranes in heart and
yeast mitochondria
M POlHL-22619-01 Cellular mechanisms of heart failure
** POlHL-22619-01 0001 Cellular mechanisms of heart
failure • Cell membrane isolation and reconstitution (dogs.
lambs)
** POlHL-22619-01 0002 Cellular mechanisms of heart
failure - Structure of sodium, potassium-adcnosine
triphosphatase (lambs, dogs)
** POlHL-22619-01 0003 Cellular mechanisms of heart
failure - Digitalis induced inotropy in myocardial ischemia
heart failure (animals)
POlHL-22619-01 0009 Cellular mechanisms of heart
failure - Sarcoplasmic reticulum in cardiac, skeletal and
smooth muscle (rabbits, dogs)
ROIHL 23593 01 Mast cell granutas- Structure and
secretion (rats)
MENADIONE
SEf VITAMIN K3
MENADIONE REDUCTASE
SEE OXIOOREDUCIASES, NAO(P)H DEHYDROGENASE
(QUINONE)
MENINGEAL HEMORRHAGES
SEE CEREBROVASCULAR DISORDERS. MENINGEAL
HEMORRHAGES
MENINGITIS BACTERIAL
SEE NERVOUS DISORDERS CENTRAL. MENINGITIS BACTERIAL
MENINGOCOCCUS
SEE BACTERIA. NEISSERIACEAE. NEISSERIA MENINGITIDIS*
MENINGOPNEUMONITIS AGENT
SEE CHLAMYDIA. MENINGOPNEUMONITIS AGENT
MENKES' KINKY HAIR SYNDROME
SEE METABOLIC DISORDERS INBORN. KINKY HAIR SYNDROME
MENSTRUATION AND MENSTRUAL CYCLE
SEE FERTILITY. SEX CYCLES. MENSTRUATION
MENTAL DEFICIENCY
SEE MENTAL RETARDATION
MENTAL DISORDERS
SEE PSYCHOLOGY ABNORMAL, MENTAL DISORDERS
(GENERAL)
MENTAL DISORDERS CHEMOTHERAPY
SEE PSYCHOLOGY ABNORMAL. MENTAL DISORDERS
CHEMOTHERAPY
MENTAL HEALTH
SEE ALSO ALCOHOL RESEARCH REVIEW COMMITTEE
SEE ALSO BEHAVIORAL SCIENCES (DEVELOPMENTAL) STUDY
SECTION
SEE ALSO EPIDEMIOLOGIC STUDIES REVIEW COMMITTEE
SEE ALSO PSYCHOLOGY. AHITUDE TO HEALTH AND HEALTH
PROBLEMS
P60HL-15162-07 0007 Comprehensive sickle cell center -
Core program -Demographic studies (human)
ROlHL-20187-01 Evaluation of exercise cardiac
rehabilitation program (40-55 year old men)
MENTAL HEALTH EPIDEMIOLOGY
SEE ALSO EPIDEMIOLOGIC STUDIES REVIEW COMMITTEE
ROlHL-19839-09 Factors in youth predisposing to chronic
diseases (former college students)
** ROlHL-20724-01 Behavioral consequences of hypertension
(human)
MENTAL HEALTH PERSONNEL ADJUNCT
R23HL-22947-01 Experimental systems to improve youth
behavior (smoking prevention)
MENTAL HEALTH SERVICES
SEE ALSO CHILD MENTAL HEALTH (SERVICES)
P50HL-15170-05 0023 Support for center for sickle cell
anemia - Comprehensive sickle cell clinic
MENTAL HEALTH SERVICES, COMMUNITY
MENTAL HEALTH SERVICES
R23HL 22947-01 Experimental systems to improve youth
behavior (smoking prevention)
MENTAL HEALTH SERVICES, COUNSELING
P60HL-20985-01 0008 Northern California sickle cell
center - Demonstration community program-Patient
ambudsman
ROlHL-21323-02 Raynaud's disease and temperature self-
regulation (human)
MENTAL HEALTH SERVICES, COUNSELING,
GROUP
SEE ALSO PSYCHOTHERAPY. GROUP THERAPY
POlHL-10539-12 0064 Pathophysiology of circulation -
Exercise physiology and pathophysiology (human)
ROlHL-209 10-02 The alternative diet for coronary disease
prevention (human)
ROlHL-21427-02 Behavioral changes in post infarction
patients
MENTAL HEALTH SERVICES, REHABILITATION
PSYCHOSOCIAL
** POlHL-10539-12 0031 Pathophysiology of circulation -
Post myocardial infarction care-Psychological aspects
(human)
POlHL-13108-09 0001 Clinical heart transplantation -
Therapy and prognosis (human)
** ROlHL-20637-02 Recovery after heart surgery-Bio-
behavioral factors (human)
MENTAL HEALTH SERVICES, SOCIAL SERVICE
PSYCHOSOCIAL
P60HL-15160-07 0017 Center for sickle cell disease -
Demonstration-Education, screening, counseling, patient
care
P60HL-15162-07 0001 Comprehensive sickle cell center
Core program-Patient care
MIT
P60HL 15999 05 0005 Miimi compr«h«n»ive »ickl» cell
center Sickle cell clinic
P60HL 16008 06 0001 Wayne Stale Univeriity
comprehensive sickle cell center Patient care jyitem
(children, adults)
P60HI 16008 06 001 1 Wayne State Univerjily
comprehensive sickle cell center Education, jcreenini and
counseling
MENTAL HEALTH (SERVICES), YOUTH
P60HL 15162 07 0001 Comprehensive sickle cell center
Core program- Patient care
** R23HL-22947 01 Experimental systems to improve youth
behavior (smoking prevention)
MENTAL PERFORMANCE
SEE PSYCHOLOGY. PERFORMANCE
MENTAL PROCESSES
SEE PSYCHOLOGY. MENTAL PROCESSES (GENERAL)
MENTAL RETARDATION
SEE ALSO CONGENITAL ABNORMALITIES. NEUROLOGICAL.
DYSAUTONOMIA FAMILIAL
SEE ALSO METABOLIC DISORDERS INBORN.
AMINOACIOOPATHIES. HOMOCYSTINURIA
SEE ALSO METABOLIC DISORDERS INBORN.
HYPOLIPOPROTEINEMIAS FAMILIAL,
ABETALIPOPROTEINEMIA
SEE ALSO METABOLIC DISORDERS INBORN, LIPID (NEUTRAL)
STORAGE, WOLMANS DISEASE
SEE ALSO METABOLIC DISORDERS INBORN.
MUCOPOLYSACCHARIDOSIS, I CELL DISEASE
POlHL-09011 15 0010 A research and resource program
in blood Chromosome changes in human genetics
POlHL-09011 15 0018 A research and resource program
in blood Hepatitis B in normal populations Epidemiology,
risk factors and transmission
POIHL 0901 1-15 0020 A research and resource program
in blood Passive immunization in the prevention of
transmission of hepatitis B (human)
POlHL-09011-15 0023 A research and resource program
in blood Evaluation of hepatitis B vaccine in endemic
settings (human)
ROlHL-15655-05 Blood flow and gas exchange in placenta
and lungs (sheep) rabbits)
MENTAL SET
SEE PSYCHOLOGY. ATTITUDES (AND RELATED)
MER
SEE BACTERIA, ACTINOMYCETALES, BACIUUS CALMETTE-
GUERIN*
MERCAPTANS
SEE THIOLS
6-MERCAPTOPURINE
SEE THIOPURINES, 6-MERCAPTOPURINE
MERCURY (COMPOUNDS)
SEE METALS, HEAVY METALS, MERCURY
MERCURY POISONING
SEE METALS POISONING, MERCURY POISONING
MEROCARBOCYANIN ES
SEE MEROCYANINES
MEROCYANINES
POlHL-161 17-05 0004 Ion movements and membranes in
cardiovascular control - Optical studies of excitation-
contraction coupling (frogs, snakes)
ROlHL-17702-04 Electro-optical dyes as probes of heart
excitability
ROlHL-20254-02 Probes of heart and nerve membranes-
Fluorescent dyes
MEROMYOSIN
SEE MUSCLE PROTEINS (AND CONTRACTILE PROTEINS),
MEROMYOSIN
MESENCEPHALON
SEE BRAIN, MESENCEPHALON
MESENTERIC VASCULAR INSUFFICIENCY
SEE GASTROINTESTINAL CIRCULATORY DISORDERS.
CIRCULATORY INSUFFICIENCY
MESENTERY
SEE BODY CAVITIES, MESENTERY
MESOCRECITUS
SEE MAMMALS, RODENTS, MYOMORPHA, HAMSTERS*
MESSENGER RIBONUCLEIC ACID
SEE NUCLEIC ACIDS, MRNA
MESTRANOL
SEE ESTRATRIENE SERIES. MESTRANOL
MESTRANOL-NORETHYNODREL COMBINATIONS
SEE FERTILITY. ANTIFERTIUTY DRUGS. MESTRANOL-
NORETHYNODREL
METABOLIC DISORDERS
SEE ALSO AMINOACIOOPATHIES, ACQUIRED
(contd)
'Excludes routine methodology OR covers only general projects which preclude i
"Oriented significantly to above subject.
indexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
Rapid specific micro measurement of
MET
SEE ALSO ARTHRITIS AND METABOLIC DISEASES PROGRAM
PROJECT COMMITTEE
SEE ALSO CARBOHYDRATES METABOLISM DISORDERS
SEE ALSO ENDOCRINOLOGY, ENDOCRINE DISORDERS
SEE ALSO GASTROINTESTINAL DISORDERS, MALABSORPTION
SYNDROMES
SEE ALSO IRON DISORDERS AND IMBAUNCES
SEE ALSO LIPOIOAL DISORDERS
SEE ALSO METAL DISORDERS AND IMBALANCES
SEE ALSO PROTEINS METABOLISM DISORDERS
ROlHL-00759-29 Regulation of electrolyte and acid base
equilibrium (dogs)
** POlHL-06835-17 0050 Cardiovascular disease ■ 18-
Hydroxylase block in the 17 alphahydroxylase deficiency
syndrome (human)
R01HL-I5810-06 Electrolyte physiology and respiratory
acid-base (dogs)
R0IHL18206-04 Regulation of metabolism in oxygen
deficient hearts (rats)
METABOUC DISORDERS CHEMOTHERAPY
ROIHLI 1901-12 0006 Effects of metabolic surgery on
the hyperlipidemias - Drug therapy with ileal bypass
(rabbits)
R01HL-12085-10 Lipoprotein-carbohydrate metabolism
(human, rats)
ROIHL- 13632-08 Vascular changes in diabetes mellitus
(human)
P50HL-14141-05 0003 SCOR for atherosclerosis in
childhood - Detection of abnormalities in lipid metabolism
(human, rabbits, rats)
*• P50HL-14237-07 0006 Support for arteriosclerosis center
■ Drug treatment of familial hyperbetallpoproteinemia
(human)
R01HL-1S308-07 Assays for peptides of lipoproteins
(human)
ROlHL-18454-03 Maximal exercise testing In
hyperlipldemic children
ROlHL-20483-03 Sterol balance and cholesterol absorption
In diabetics (human)
METABOUC DISORDERS DIAGNOSIS*
SEE ALSO METABOLIC DISORDERS INBORN DIAGNOSIS*
P01HL-0628S-18 0149 Cardiovascular-respiratory
physiology and biochemistry - Microangiopathy in
predlabetic and diabetic subjects (human)
** R0IHL-1S26306 Lecithin -Cholesterol acetyltransferase
(human, rabbits)
ROlHL-19083-02
blood cholesterol
ROlHL-20539-03 Blood glucose, hemoglobin Ale, and
diabetic vascular disease (human)
ROlHL-22567-01 Validation of a cholesterol absorption
method in man
METABOLIC DISORDERS INBORN
SEE ALSO BLOOD COAGULATION DISORDERS,
AFIBRINOGENEMIA
SEE ALSO BLOOD COAGULATION DISORDERS, CHRISTMAS
DISEASE
SEE ALSO BLOOD COAGULATION DISORDERS, FACTOR VII
DEFICIENCY
SEE ALSO BLOOD COAGUUTION DISORDERS, FACTOR XI
DEFICIENCY
SEE ALSO BLOOD COAGULATION DISORDERS, HEMOPHILIA
SEE ALSO BLOOD COAGUUTION DISORDERS, VON
WILLEBRAND'S DISEASE
SEE ALSO BLOOD PROTEINS DISORDERS CONGENITAL
SEE ALSO CONGENITAL ABNORMALITIES
SEE ALSO HEMOPROTEINS, HEMOGLOBINOPATHIES
SEE ALSO HEMOPROTEINS, MYOGLOBINOPATHIES
SEE ALSO LIPOGRANULOMATOSES, CEREBROTENDINOUS
XANTHOMATOSIS
SEE ALSO LIPOGRANULOMATOSES, LIPOID PROTEINOSIS
SEE ALSO PURINES-PYRIMIDINES METABOLISM ERRORS
P01HL-09011-1S 0010 A research and resource program
In blood - Chromosome changes In human genetics
** ROlHL-12944-09 Enzymatic and biochemical studies on
blood cells (human)
** R01HL-1512S-07 Molecular pathology of genetic disorders
In man
P60HL- 17265-04 0008 Community blood resource center
support - Research-Blood genetic markers as biological
probes (human)
METABOUC DISORDERS INBORN,
ACATAIASEMIA
ROlHL-21756-11 Vascular disease -Cytochemistry and
ultrastructure (human, rats, mice, hamsters)
METABOUC DISORDERS INBORN,
AMINOACIDOPATHIES
ROlHL-15980-06 Reactions of hemeprotelns and oxygen
(cattle)
METABOUC DISORDERS INBORN,
AMINOACIDOPATHIES, HOMOCYSTINURIA
ROlHL-05062-18 Lipid metabolism in cultured cells
(human, rats, rabbits)
ROlHL-1 1775-11 Platelet mechanisms in disease (human,
primates)
338
METABOUC DISORDERS (INBORN),
AMYLOIDOSIS
** POlHL-03174-23 0002 Mechanisms of acute vascular
reaction to injury ■ Chemical structure, pathological
significance of amyloid substance (human, mice)
ROlHL-1660305 Human and experimental renal diseases
(animals)
METABOUC DISORDERS INBORN,
ANGIONEUROTIC EDEMA (HEREDITARY)
** ROlHL-15690-07 Hydrolytic enzymes of blood in health
and disease (human, animals)
METABOUC DISORDERS (INBORN), ANTITRYPSIN
DEFICIENCY
R01HL-10009-13 Regional lung function in man
R01HL12530-10 Emphysema -Respiratory function in
disease (human, dogs, rats)
** ROlHL-1283309 Genetic and environmental Influences on
lung disease (human)
P50HL-14136-07 0009 Pulmonary SC0R-Alrv»ays
obstructive diseases - Tuscon epidemiological study of
airways obstructive disease (human)
P50HL-141 53-07 0001 Johns Hopkins Lung Center-
Chronic diseases of airways - Genetic and environmental
factors in chronic pulmonary disease (human)
ROlHL-14262-07 Leukocyte proteases and their lung
targets (human, dogs, rabbits)
** ROlHL-14692-06 Alpha 1 antitrypsin deficiency and
pulmonary disease (human)
** ROIHL-14700-05 Humoral and lung protease-antiprotease
role In obstructive disease (human)
ROlHL-14865-07 Biochemical studies on the pathogenesis
of emphysema (human, rats)
R01HL-I512S-07 Molecular pathology of genetic disorders
in man
POlHL-15832-06 0004 Chemical-structural predispositions
to lung injury - Proteolytic activity leucocytes In patients
with obstructive lung disease
POlHL-161 18-06 0004 Study of emphysema Metabolic
activity of pulmonary connective tissue (human, hamsters)
" ROlHL-17194-03 Comparison of two inherited forms of
atpha-1-antitrypsin (human)
P50HL-191 71-02 0003 Pulmonary SCOR -Lung injury by
childhood infections - Natural history, host defense defects-
Children with chronic pulmonary disease
** ROIHL 20070-02 Alpha-1-antitrypsin deficiency (human,
hamsters)
ROlHL-20875-02 Chronic obstructive pulmonary dlsease-
Familial/genetlc (human)
** ROlHL-21 156-02 Antitrypsin and other causes of chronic
lung disease
** ROlHL-23595-01 Experimental emphysema-Depression of
protease Inhibitors (rats, hamsters)
METABOUC DISORDERS INBORN, BARTTER'S
SYNDROME
ROlHL-l 1046-12 Renin, angiotensin, steroids. Ions and
blood pressure (human, sheep, rabbits)
ROlHL-13595-08 Renin and vascular hyper-reactivity in
hypertension (human, rats)
P01HL-14388-07 0179 Regulation of the circulation In
pathological states - Cultured muscle cells and their cross-
innervatlon in vitro (rats, sheep)
ROlHL-l 7705-04 Kalllkrein-kinin system In hypertension
(human, rats, dogs)
** ROlHL-19428-03 Role of angiotensin sensitivity in renin
release (human)
R01HL-21272-02 Sodium homeostasis and renal
prostaglandins (dogs)
** ROlHL-23602-01 Physiology of renin, aldosterone and
prostaglandin (human, rats, dogs)
METABOUC DISORDERS INBORN, CEREBRO-
HEPATO-RENAL SYNDROME
ROlHL-21756-11 Vascular disease-Cytochemistry and
ultrastructure (human, rats, mice, hamsters)
METABOUC DISORDERS INBORN, CHEDIAK-
HIGASHI SYNDROME
POlHL-06314-17 0047 Immunologic mechanisms in
cardiovascular disease - Role of Intravascular coagulation
(human, animals)
METABOUC DISORDERS INBORN, CYSTIC
FIBROSIS
POIHL-07896-15 0021 Environmental biomedical research
program - Liquid breathing and lung lavage (human)
POlHL-08214-15 0006 Chemical and biological properties
of lipids - Analysis and properties of lipids
POlHL-10436-13 0005 A multidisciplinary study of
congenital heart disease - Pulmonary physiology in
congenital heart disease (human)
POlHL-10436-13 0008 A multidisciplinary study of
congenital heart disease - Physiologic consequences of
chronic hypoxemia (human)
M ROlHL-13885-08 Cystic fibrosis and pulmonary disease
** ROlHL-13885-08 0005 Cystic fibrosis and pulmonary
disease - Evaluation of lobar pulmonary lavage (human)
** ROIHL-13885-08 0006 Cy:tic fibrosis and pulmonary
disease - Cell mediated immunity and Pseudomonas
infections in cystic fibrosis (human)
MET
ROlHL-13885-08 0007 Cystic fibrosis and pulmonary
disease - Alveolar macrophage defense mechanism
(human, rabbits)
ROlHL-13885-08 0008 Cystic fibrosis and pulmonary
disease - Pseudomonas specific activation of alveolar
macrophages (human, rabbits)
ROIHL- 13885-08 0009 Cystic fibrosis and pulmonary
disease - Respiratory mucus glycoproteins (human, rabbits)
ROlHL-13885-08 9001 Cystic fibrosis and pulmonary
disease • Pulmonary function core facility (infants,
children)
ROIHL- 13885 08 9002 Cystic fibrosis and pulmonary
disease - Computer core facility (human)
ROIHL- 13885-08 9003 Cystic fibrosis and pulmonary
disease - Fiberoptic bronchoscopy core facility (human,
dogs, sheep)
Pulmonary SCOR-Alrways
Acute pediatric respiratory disease
P50HL-14136-07 0003
obstructive diseases
and COLD
P50HL-14136-07 0017
obstructive diseases
(human)
P50HL-14136-07 9005
obstructive diseases
Pulmonary SCOR-Alrways
Pediatric airways obstructive disease
iKkidts iwitine nwUiodokigy OR coven only general projects which preclude Indexing at the specific level.
**9n^<4«4 (ifnificaiitly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for Investigator's name and grant number.
Pulmonary SCOR-Airways
Clinical core
** ROlHL-14844-06 Mucous glycoprotein In human respiratory
epithelium (also wheat)
ROlHL-15526-05 Respiratory mechanics in children
** ROlHL-17776-04 Pulmonary mucus transport in
obstructive lung diseases (human)
POlHL-18574-03 0001 Lipoprotein methodology and
biomedical applications - Ultracentrifugal and
electrophoretic lipoprotein methodology-Applications
M P50HL19157-02 Studies in cystic fibrosis and
bronchiolitis
** P50HL-1915702 0001 Studies in cystic fibrosis and
bronchiolitis - Laboratory core unit
** P50HL-19157-02 0002 Studies in cystic fibrosis and
bronchiolitis - Clinical core
*• P50HL-I9157-02 0003 Studies in cystic fibrosis and
bronchiolitis - Nasal mucosal function In patients with
cystic fibrosis
** P50HL-19157-02 0004 Studies In cystic fibrosis and
bronchiolitis - Macromolecular regulators of mucus
secretion-Invertebrate model
** P50HL-19157-02 0007 Studies in cystic fibrosis and
bronchiolitis - Analysis of cystic fibrosis factors (human)
** P50HL-19157-02 0008 Studies In cystic fibrosis and
bronchiolitis - Serum proteins In cystic fibrosis (human)
** P50HL-19157-02 0009 Studies in cystic fibrosis and
bronchiolitis - Polyamine metabolism In cystic fibrosis
(human, rat)
M P50HL-19160-02 Mucus abnormality in cystic fibrosis
" P50HL-19160-02 0001 Mucus abnormality in cystic
fibrosis - Regulation of respiratory secretions (rat, human)
** P50HL-19160-02 0002 Mucus abnormality In cystic
fibrosis ■ Ultrastructure, cytochemistry of pulmonary
secretion (human, rat)
P50HL-19171-02 0003 Pulmonary SCOR-Lung Injury by
childhood Infections - Natural history, host defense defects-
Children with chronic pulmonary disease
ROlHL-20675-02 Alveolar macrophage function in man
** R23HL-21150-02 Regulation of airway mucous glands and
ion transport (dogs, ascarls)
** ROlHL-2 11 56-02 Antitrypsin and other causes of chronic
lung disease
ROlHL-21314-02 Respiratory tract secretion of ions, water
and mucus (human, dogs)
** R23HL-21954-01 Exercise conditioning in patients with
cystic fibrosis
** R23HL-22818-01 Biosynthesis of human respiratory
mucous glycoprotein (also dog)
** NOlHR-7292001 Identify and quantify cystic fibrosis
factors (human)
** NOlHR-72921-01 Cystic fibrosis factor identification and
quantification (human)
** NOlHR-72922-01 Cystic fribrosis factor identication and
quantification (human)
** NOlHR-72923-01 Cystic fibrosis factor identification and
quantification (human)
METABOLIC DISORDERS (INBORN), DIABETES
INSIPIDUS
SEE ALSO PITUITARY-DIENCEPHALON HORMONES,
VASOPRESSIN
R01HL-00340-29 Electrolyte disturbance in cardlo-renal
disease (human, dogs, rats)
POlHL-12738-10 0114 Physiologic pharmacology and its
clinical applications - Receptor specificites and metabolism
of neurohypophysial hormones (rats)
R01HL19209-03 Role of ADH in experimental renal
hypertension (dogs, rats)
ROlHL-2241101 Neuroendocrine involvement in
hypertension (rats)
METABOUC DISORDERS INBORN,
DISACCHARIDE (OLIGOSACCHARIDE)
INTOLERANCE
R01HL-15797-05 Lipid metabolism and atherosclerosis in
primates (monkeys, human, squirrels)
(contd)
MET
METABOLIC DISORDERS INBORN, EHLERS-
DANIOS SYNDROME
POIHI 18b76 03 0004 Thiombosis tosestch ptogiam
project Mechanism and conliol ot collagen platelet
inteiaclion
METABOLIC DISORDERS INBORN, GLUCOSE-6-
PHOSPHATE DEHYDROGENASE DEFICIENCY
SEE ALSO OXIOOREOUCTASES. GLUCOSE 6 PHOSPHATE
DEHYDROGENASE
RCIHL 07449 17 Foimation and survival ol red blood cells
(human)
P60HL 15157 07 0001 Comprehensive center lor sickle
cell disease ■ Screening program (human)
P60HI 15157 07 0003 Comprehensive center tor sickle
cell disease Public education
P60H1. 15157 07 0012 Comprehensive center lor sickle
cell disease Sickling and intracellular pH (human)
P60HL 15158 07 0004 Comprehensive sickle cell center ■
Expression ot abnormal hemoglobin synthesis in the
neonate and young child
P60HL 15168 07 0001 Comprehensive sickle cell disease
center Screening program (human)
P60HL 1600505 9001 Comprehensive sickle cell center ■
Core laboratory and counseling (human)
•* POIHL 20993 02 0003 Population dynamics of arterial
cells in atherogenesis Clonal phenomena in atherogenesis
(human, hares)
METABOLIC DISORDERS INBORN,
GLYCOGENOSIS
SEE ALSO PHOSPHOMONOESTERASES. GLUCOSE 6-
PHOSPHATASES
ROlHL-0622117 Composition and structure of plasma
lipoproteins (human, turkeys, baboons)
METABOLIC DISORDERS INBORN,
GLYCOGENOSIS, TYPE III
ROlHL-1512507 Molecular pathology of genetic disorders
in man
METABOLIC DISORDERS INBORN,
HEMOCHROMATOSIS
R01HL07449-17 Formation and survival of red blood cells
(human)
METABOLIC DISORDERS INBORN,
HEPATOLENTICULAR DEGENERATION
ROlHL-2175611 Vascular disease-Cytochemistry and
ultrastructure (human, rats, mice, hamsters)
METABOLIC DISORDERS INBORN,
HYPERLIPOPROTEINEMIAS FAMILIAL
ROlHL-0622117 Composition and structure of plasma
lipoproteins (human, turkeys, baboons)
R01HL-06222-18 Clinical and laboratory studies in lipid
metabolism (human, mammals, non-human)
** POlHL-06835-17 0026 Cardiovascular disease -
Lipoproteins (human, guinea pig)
** POlHL-06835-17 0062 Cardiovascular disease - Role of
collagen in atherosclerosis (dogs, pigeons)
** POlHL-06835-17 0064 Cardiovascular disease - Studies
in atherosclerosis (human, animals)
ROlHL-1 1901-12 0013 Effects of metabolic surgery on
the hyperlipidemias - Human cholesterol and bile acids
dynamics-lleal bypass
ROlHL-13626-06 Lipoprotein lipase and lipoprotein
removal (human, rats, bacteria)
M P50HL-14197-07 Support for center of research on
arteriosclerosis
** P50HL-14197-07 0005 Support for center of research on
arteriosclerosis - Lipoprotein biosynthesis and degradation
in vivo and in vitro (human, animal)
P50HL-14197-07 0006 Support for center of research on
arteriosclerosis - Diets and drugs affecting lipid
metabolism (human)
** P50HL-14197-07 0007 Support for center of research on
arteriosclerosis - Metabolic defects in familial
hyperiipoproteinemias (human)
** P50HL-14237-07 0005 Support for arteriosclerosis center
- Genetic determinants of apolipoprotein variability in
lipoproteins (human)
P5OHL-15062-07 0001 Study of lipoproteins, artery v»all,
and atherosclerosis - Structure and molecular interactions
of serum lipoproteins (human, monkey)
P50HL-15103-07 0001 A/S SCOR -Early natural history of
arteriosclerosis - Clinical research-Bogalusa heart study
(children)
POlHL-15596-05 0001 Coagulation, fibrinolysis,
hemostasis and hepatitis - Defibrination (human)
** ROlHL-16774-04 Genetic epidemiology of hyperiipemia
(Honolulu)
** P60HL- 17269-04 0001 National heart and blood vessel
research and demonstration center - Atherosclerosis-
Arterial pathology and plasma lipids (human)
P60HL-17269-04 0015 National heart and blood vessel
research and demonstration center - Lipoprotein
metabolism laboratory (human)
** ROlHL-18687-03 Pathophysiology of genetic
hypertriglycerinemias (human)
** ROlHL-19095-03 Laser spectroscopy of lipoproteins
(human)
339
•• ROIHL 70391 03 Potydispersc IDl Steuctuie, metabolism
and function (human)
M POIHI 20948 U2 Molecular basis of cholesterol
metabolism
•* POIHI 20948 02 0003 Molecular basis ol Cholesterol
metabolism LDL pathv<ay in vivo (human, rats, guinea
pigs)
POIHL 20948 02 0004 Molecular basis ol cholesterol
metabolism Genetic analysis ot the LDL pathway (human)
ROIHL 20954 02 Hyperlipoproteinemia (rats, human)
P50HL 2100602 0001 Specialized center ol research in
arteriosclerosis Clinic and core program
P50HL 21006 02 0002 Specialized center ol research in
arteriosclerosis ■ Turnover and metabolism ol cholesterol in
man
ROIHL 22456 01 Lipoproteins in bioregulation ol the
immune response (mice, human)
** R01HL22618-01 Role ol apolipoproteins in
hypertriglyceridemia (human)
** POIHL 22619-01 0012 Cellular mechanisms ol heart
lailure Apolipoproteins in hypertriglyceridemia (human)
METABOLIC DISORDERS INBORN,
HYPERLIPOPROTEINEMIAS FAMILIAL, TYPE I
ROlHL-06221-17 Composition and structure ol plasma
lipoproteins (human, turkeys, baboons)
P50HI 14197 07 0007 Support for center of research on
arteriosclerosis Metabolic defects in familial
hyperlipoproteinemias (human)
ROlHL-15895-05 In vitro study of lipoproteins in vascular
disease (human, animals)
ROlHL-226 18-01 Role of apolipoproteins in
hypertriglyceridemia (human)
ROIHL 2296701 Structure and function of heparin
releasable lipases (sviinc, human)
METABOLIC DISORDERS INBORN,
HYPERLIPOPROTEINEMIAS FAMILIAL, TYPE II
ROlHL-05062-18 Lipid metabolism in cultured cells
(human, rats, rabbits)
R01HL08634-15 Enzymic cholesterol synthesis (human,
rats, protozoa, yeast)
** R01HL11901-12 0009 Effects of metabolic surgery on
the hyperlipidemias - Cholesterol cord blood and family
management program
ROlHL-12085-10 Lipoprotein carbohydrate metabolism
(human, rats)
P50HL-14197-07 0005 Support for center of research on
arteriosclerosis - Lipoprotein biosynthesis and degradation
in vivo and in vitro (human, animal)
P50HL-141 97-07 0007 Support for center of research on
arteriosclerosis - Metabolic defects in familial
hyperlipoproteinemias (human)
P50HL-1423007 0088 A/S SCOR -Lipids, atherosclerosis
and thrombosis - Coronary risk factors in school children-
The Muscatine study
" P50HL-14230-07 0093 A/S SCOR-Lipids. atherosclerosis
and thrombosis - Clinical studies involving cellular lipid
content (human)
P50HL-14230-07 0097 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Studies of circulating platelet aggregates
(human)
** P60HL14237-07 0006 Support for arteriosclerosis center
- Drug treatment of familial hyperbetalipoproteinemia
(human)
P50HL- 15062-07 0013 Study ol lipoproteins, artery wall,
and atherosclerosis ■ Radioimmunoassay of apolipoproteins
(human, monkeys)
R01HL15308-07 Assays for peptides of lipoproteins
(human)
POlHL-15596-05 0018 Coagulation, fibrinolysis,
hemostasis and hepatitis - Increased plasma lipids on
blood coagulation and thrombosis (human, animals)
ROlHL-15895-05 In vitro study of lipoproteins in vascular
disease (human, animals)
ROlHL-15949-05 Lipoprotein metabolism in relation to
atherosclerosis (human, baboons)
ROlHL-178 18-05 Metabolism of cholesterol and cholesterol
in man (also rats, monkeys)
** ROlHL-17898-03 Cell membranes and plasma lipoproteins
(human, swine)
** ROlHL-18454 03 Maximal exercise testing in
hyperiipidemic children
** ROlHL-18553-03 Membrane defects in familial
hypercholesteremia (human)
** P01HL-18827-02 0005 Platelet vessel wall interactions in
thrombogenesis - Platelet vessel wall interactions in
thrombogenesis (human)
** ROlHL-188 78-03 Familial hypercholesteremia-Studies of
fibroblasts (human)
R01HL-19084-03 Structure and function of serum
lipoproteins (human)
ROlHL-19095-03 Laser spectroscopy of lipoproteins
(human)
ROlHL-191 75-03 Pituitary modulation of micro-and macro-
vascular disease (human, rats)
ROlHL-201 83-02 Portacaval shunt as treatment for
hyperiipemia (pigs)
ROlHL-202 18-02 Fibrinogen catabolism and intravascular
coagulation (human)
" ROlHL-2048303 Sterol balance and cholesterol absorption
in diabetics (human)
MIT
•• ROIHI 20807 02 Detection ol Inmilial hyptrcholeiltrolemu
(human)
ROIHI 21460 0? Lipoprotein^,, hemostasis and
alheroscleroMS (human, rabbits)
ROIHL 224/4 01 Cholesterol metabolism and
atherosclerosis (rats, human, rabbiti)
ROIHI 22607 01 Role ol apolipoprotein [ in lipoprotein
metabolism (human)
ROIHL 22618 01 Role ol apolipoproteins in
hypertriglyceridemia (human)
•* POIHL 22633 01 0003 Cellular and molecular biology ol
lipoprotein metabolism Sterol metabolism in platelets and
megakaryocytes (human, rabbits, guinea pigs)
ROIHI 22748 01 Effect of bile sequestration on VIDL
metabolism (human)
** NOIHV 12156 10 Lipid research clinic
** NOIHV 12157 14 Lipid research clinic (human)
•* NOIHV 12158 10 Establishment of a lipid research clinic
NOIHV 12160 15 Establishment of a lipid research clinic
NOIHV 2291309 lipid research clinic
NOIHV 22914 08 Establishment of a lipid research clinic
METABOLIC DISORDERS INBORN,
HYPERLIPOPROTEINEMIAS FAMILIAL, TYPE III
ROIHL 12085 10 Lipoprotein carbohydrate metabolism
(human, rats)
P50HL 1419707 0007 Support for center ol research on
arteriosclerosis Metabolic defects in familial
hyperlipoproteinemias (human)
P50HL 14230-07 0097 A/S SCOR-Lipids, atherosclerosis
and thrombosis Studies of circulating platelet aggregates
(human)
P50HL15103 07 0013 A/S SCOR- Early natural history of
arteriosclerosis Experimental models of atherosclerosis
(monkeys)
ROlHL-15308-07 Assays for peptides of lipoproteins
(human)
ROlHL-15895-05 In vitro study of lipoproteins in vascular
disease (human, animals)
** P60HL 17269-04 0045 National heart and blood vessel
research and demonstration center - Regulation of
lipogenesis in hypcriipoproteinemia (human, tissue culture)
POlHL-1857403 0004 Lipoprotein methodology and
biomedical applications - Fine structure and metabolism of
lipoproteins-EM studies (guinea pigs)
ROlHL-18687-03 Pathophysiology of genetic
hypertriglycerinemias (human)
ROlHL-19095-03
(human)
Laser spectroscopy of lipoproteins
Detection of familial hypercholesterolemia
R01HL-20807-02
(human)
R01HL-21460-02 Lipoproteins, hemostasis and
atherosclerosis (human, rabbits)
** ROlHL-22607-01 Role of apolipoprotein E in lipoprotein
metabolism (human)
ROlHL-226 18-01 Role of apolipoproteins in
hypertriglyceridemia (human)
NOlHV-12157-14 Lipid research clinic (human)
METABOLIC DISORDERS INBORN,
HYPERLIPOPROTEINEMIAS FAMILIAL, TYPE IV
ROlHL-05062-18 Lipid metabolism in cultured cells
(human, rats, rabbits)
ROlHL-06221-17 Composition and structure of plasma
lipoproteins (human, turkeys, baboons)
ROlHL-12085-10 Lipoprotcincarbohydrate metabolism
(human, rats)
P50HL-14197-07 0007 Support for center of research on
arteriosclerosis - Metabolic defects in familial
hyperiipoproteinemias (human)
P50HL-14230-07 0097 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Studies of circulating platelet aggregates
(human)
ROlHL-15308-07 Assays for peptides of lipoproteins
(human)
POlHL-15596-05 0018 Coagulation, fibrinolysis,
hemostasis and hepatitis ■ Increased plasma lipids on
blood coagulation and thrombosis (human, animals)
ROlHL-1589505 In vitro study of lipoproteins in vascular
disease (human, animals)
R01HL-16807-02 Lipid structure of normal and
hyperiipoproteins (human)
ROlHL-17462-03 Role of glycosphingolipids in platelet
aggregation (rats, human, dogs)
ROlHL-1781805 Metabolism of cholesterol and cholesterol
in man (also rats, monkeys)
POlHL-18545-03 0004 Biology of the artery wall and
atherosclerosis - Human arterial smooth muscle cell and
lipoprotein interaction
POlHL-1882702 0001 Platelet vessel wall interactions in
thrombogenesis - Role of endothelial cells in the production
of thrombi (human, cattle)
ROlHL-19095-03 Laser spectroscopy of lipoproteins
(human)
ROlKL-19175-03 Pituitary modulation of micro-and macro-
vascular disease (human, rats)
ROlHL-20218-02 Fibrinogen catabolism and intravascular
coagulation (human)
ROlHL-20391 03 Polydisperse LDL -Structure, metabolism
and function (human)
** ROlHL-20483-03 Sterol balance and cholesterol absorption
in diabetics (human)
(contd)
•Excludes routine methodology OR covers only general projects which preclude
"Oriented significantly to above subject.
indexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for Investigator's name and grant number.
MET
ROlHL-21460-02 Lipoproteins, hemostasis and
atherosclerosis (humanr rabbits)
ROlHL-22618-01 Role of apolipoproteins in
hypertriglyceridemia (human)
R01HL-22''48-01 Effect of bile sequestration on VLOL
metabolism (human)
METABOLIC DISORDERS INBORN,
HYPERLIPOPROTEINEMIAS FAMILIAL, TYPE V
ROlHL-06221-17 Composition and structure of plasma
lipoproteins (human, turkeys, baboons)
R01HL12085-10 Lipoproteincarbohydrate metabolism
(human, rats)
P50HL 1419707 0005 Support for center of research on
arteriosclerosis Lipoprotein biosynthesis and degradation
in vivo and in vitro (human, animal)
P50HL-14197-07 0007 Support for center of research on
arteriosclerosis - Metabolic defects in familial
hyperlipoproteinemias (human)
P01HL1559605 0018 Coagulation, fibrinolysis,
hemostasis and hepatitis - Increased plasma lipids on
blood coagulation and thrombosis (human, animals)
R01HL15895-05 In vitro study of lipoproteins in vascular
disease (human, animals)
R01HL168O7-O2 Lipid structure of normal and
hyperlipoproteins (human)
P01HL-18827-02 0001 Platelet vessel wall interactions in
thrombogenesis - Role of endothelial cells in the production
of thrombi (human, cattle)
R01HL-22e'8-01 Role of apolipoproteins in
hypertiiglyceridemia (human)
METABOLIC DISORDERS INBORN,
HYPOLIPOPROTEINEMIAS FAMILIAL,
ABETALIPOPROTEINEMIA
ROlHl-06221-17 Composition and structure of plasma
lipoproteins (human, turkeys, baboons)
** R01HL0648M5 Lipid metabolism (human, rats)
R0IHL-15895-05 In vitro study of lipoproteins in vascular
disease (human, animals)
P01HL18574-03 0006 Lipoprotein methodology and
biomedical applications - Lipoprotein transformation.
lipolytic enzymes, diet and lipid lowering agents
POlHL-18577-03 0001 Lipoproteins-Cell surface
interactions - Structural studies of serum lipoproteins in
man anu dogs
METABOLIC DISORDERS INBORN,
HYPOLIPOPROTEINEMIAS FAMILIAL, TANGIER
DISEASE
R01HL'0e221-17 Composition and structure of plasma
lipop'oteins (human, turkeys, baboons)
R01HL15895-05 In vitro study of lipoproteins in vascular
disease (human, animals)
POlHL-18574-03 0004 Lipoprotein methodology and
biomedical applications - Fine structure and metabolism of
lipoproteins -EM studies (guinea pigs)
METABOLIC DISORDERS INBORN,
HYPOPHOSPHATASIA
SEE ALSO PHOSPHOMONOESTERASES, ALKALINE
PHOSPHATASE
ROlHL-21756-11 Vascular disease -Cytochemistry and
ultrastructure (human, rats, mice, hamsters)
METABOLIC DISORDERS INBORN, KINKY HAIR
SYNDROME
ROlHL-2175611 Vascular disease -Cytochemistry and
ultrastructure (human, rats, mice, hamsters)
METABOLIC DISORDERS INBORN, LCAT
DEFICIENCY
** ROlHL-10642-18 Plasma cholesterol metabolism (human.
macaca)
** ROIHL-1526306 Lecithin -Cholesterol acetyltransferase
(human, rabbits)
POlHL-18574-03 0004 Lipoprotein methodology and
biomedical applications - Fine structure and metabolism of
lipoproteins -EM studies (guinea pigs)
POlHL-18574-03 0005 Lipoprotein methodology and
biomedical applications Structure and function of
lipoproteins
POlHL-18645-03 0001 Biology of the artery wall and
atherosclerosis - Primate arterial smooth muscle and
atherosclerosis
ROlHL-23945-06 Pathologic effects on cells of modified
lipoproteins (rats, human)
METABOLIC DISORDERS INBORN, LIPID
(NEUTRAL) STORAGE
SEE ALSO LIPOGRANULOMATOSES. CEREBROTENOINOUS
XANTHOMATOSIS
ROlHL-18623-12 Physical chemistry of biologically active
lipids (bacteria, plant, cattle, human)
NOlHV-53015-09 Establishment of a lipid research clinic
(human)
METABOLIC DISORDERS INBORN, LIPID
(NEUTRAL) STORAGE, CHOLESTEROL ESTER
STORAGE DISEASE
ROIHL 15835-05 In vitro study of lipoproteins in vascular
disease (human, animals)
340
ROlHL-18723-03 Genetic heterogeneity of acid lipase-
Atherosclerosis (human)
METABOLIC DISORDERS INBORN, UPID
(NEUTRAL) STORAGE, WOLMAN'S DISEASE
ROlHL-18723-03 Genetic heterogeneity of acid lipase -
Atherosclerosis (human)
METABOLIC DISORDERS INBORN, LYSOSOMAL
DISORDERS
SEE ALSO BLOOD AND RE DISORDERS. LEUKOCYTE
DISORDERS. PHAGOCYTE DYSFUNCTION
(GENERAL)
SEE ALSO METABOLIC DISORDERS INBORN. ACATALASEMIA
SEE ALSO METABOLIC DISORDERS INBORN. CHEDIAK-HIGASHI
SYNDROME
SEE ALSO METABOLIC DISORDERS INBORN. GLYCOGENOSIS
SEE ALSO METABOLIC DISORDERS INBORN.
HYPOPHOSPHATASIA
SEE ALSO METABOLIC DISORDERS INBORN. LIPID (NEUTRAL)
STORAGE
SEE ALSO METABOLIC DISORDERS INBORN.
MUCOPOLYSACCHARIDOSIS. I-CELL DISEASE
P50HL-1421708 0059 Specialized center of research in
thrombosis - Energy metabolism and platelet function
(human)
ROlHL-14595-07 Primary disorders of platelet function
(human, rats)
ROlHL-21756-11 Vascular disease -Cytochemistry and
ultrastructure (human, rats. mice, hamsters)
METABOLIC DISORDERS INBORN, MARFAN
SYNDROME
" ROlHL-1 790904 Drug treatment of vascular scleroprotein
defects (human, turkeys)
METABOLIC DISORDERS INBORN,
MUCOPOLYSACCHARIDOSIS, l-CEU DISEASE
P50HL-14197-07 0005 Support for center of research on
arteriosclerosis - Lipoprotein biosynthesis and degradation
in vivo and in vitro (human, animal)
METABOLIC DISORDERS INBORN, MUSCULAR
DYSTROPHY
P01HL16607-05 0006 Calcium ion and control of
cardiovascular function ■ Sarcomere and contractile
dynamics of striated muscle cells (animals)
POlHL-16607-05 0007 Calcium ion and control of
cardiovascular function - Ultrastructure and conformation
in sarcoplasmic reticulum (rabbits)
R01HL19068-03 Changes In membrane properties during
erythropoiesis (chick embryo)
METABOLIC DISORDERS INBORN, MYOTONIA
ATROPHICA
ROlHL-19639-02 Permeability transients of carriers,
channels and heart
R01HL-2024I-02 Shear and area moduli for abnormal red
cell membranes (human)
METABOLIC DISORDERS INBORN, MYOTONIA
CONGENITA
ROlHL-22985-01 Properties and assembly of Z-disk
proteins (human, other species)
METABOLIC DISORDERS INBORN, OBESITY
HEREDITARY HYPERGLYCEMIC
** POlHL-06285-18 0150 Cardiovascular-respiratory
physiology and biochemistry - Basement membrane width
in non-diabetic hyperglycemia
METABOUC DISORDERS INBORN,
PHOSPHOGLYCERATE KINASE DEFICIENCY
ROlHL-15125-07 Molecular pathology of genetic disorders
in man
METABOLIC DISORDERS (INBORN), PORPHYRIA
ROlHL-21756-11 Vascular disease-Cytochemistry and
ultrastructure (human, rats. mice, hamsters)
METABOLIC DISORDERS INBORN, PORPHYRIA,
PROTOPORPHYRIA
ROlHL-22252-01 Synthesis of labeled hemes for protein
NMR studies
METABOLIC DISORDERS INBORN, PYRUVATE
KINASE DEFICIENCY
POlHL-18208-04 0001 Center for the study of blood cell
rheology - Physiological basis of reversible erythrocyte
shape change (human, firefly)
METABOLIC DISORDERS (INBORN), RENAL
TUBULAR ACIDOSIS
ROlHL-00340-29 Electrolyte disturbance in cardio-renal
disease (human, dogs, rats)
ROlHL-11046-12 Renin, angiotensin, steroids, ions and
blood pressure (human, sheep, rabbits)
METABOLIC DISORDERS INBORN, TRANSPORT
DISORDERS
SEE ALSO METABOLIC DISORDERS INBORN, BARTTERS
SYNDROME
SEE ALSO METABOLIC DISORDERS INBORN, CYSTIC FIBROSIS
SEE ALSO METABOLIC DISORDERS (INBORN), RENAL
TUBUUR ACIDOSIS
MET
ROlHL-2175611 Vascular disease -Cytochemistry and
ultrastructure (human, rats, mice, hamsters)
METABOLIC DISORDERS INBORN DIAGNOSIS*
SEE ALSO DIAGNOSTIC TESTS, CYTODIAGNOSIS,
CILIOINHIBITORY TEST*
** R01HL-U901-12 0009 Effects of metabolic surgery on
the hyperlipidemias - Cholesterol cord blood and family
management program
ROlHL-14865-07 Biochemical studies on the pathogenesis
of emphysema (human, rats)
ROlHL-15308-07 Assays for peptides of lipoproteins
(human)
** R01HL15949-05 Lipoprotein metabolism in relation to
atherosclerosis (human, baboons)
ROIHL 17194-03 Comparison of two inherited forms of
alpha-l-antitrypsin (human)
ROlHL-17818-05 Metabolism of cholesterol and cholesterol
in man (also rats, monkeys)
R01HL-17898-03 Cell membranes and plasma lipoproteins
(human, swine)
** R01HL19095-03 Laser spectroscopy of lipoproteins
(human)
" P50HL-1915702 0001 Studies in cystic fibrosis and
bronchiolitis Laboratory core unit
P50HL-1915702 0007 Studies in cystic fibrosis and
bronchiolitis - Analysis of cystic fibrosis factors (human)
** ROIHL-21156-02 Antitrypsin and other causes of chronic
lung disease
ROlHL-21756-11 Vascular disease-Cytochemistry and
ultrastructure (human, rats, mice, hamsters)
** NOlHR-72920-01 Identify and quantify cystic fibrosis
factors (human)
** NOlHR-7292201 Cystic fribrosis factor identication and
quantification (human)
** N01HR-7292301 Cystic fibrosis factor identification and
quantification (human)
N01HV-12157-I4 Lipid research clinic (human)
METABOLISM*
SEE ALSO BIOENERGETICS
SEE ALSO BRAIN METABOLISM
SEE ALSO CALCIUM (MINERAL) BAUNCE (METABOLISM)
SEE ALSO CARBOHYDRATES METABOLISM
SEE ALSO ENDOCRINOLOGY, HORMONES METABOLISM
SEE ALSO FATTY ACIDS METABOLISM
SEE ALSO FATTY ACIDS METABOLISM, PROSTAGUNDINS
METABOLISM
SEE ALSO HEMOPROTEINS METABOLISM
SEE ALSO LIPIDS METABOLISM
SEE ALSO LIVER METABOLISM
SEE ALSO MUSCLE METABOLISM
SEE ALSO NEUROTRANSMITTERS METABOLISM
SEE ALSO NITROGEN BALANCE
SEE ALSO NUCLEIC ACIDS METABOLISM
SEE ALSO PROTEINS METABOLISM
SEE ALSO STEROID METABOLISM
SEE ALSO TOXICOLOGY. TOXICANT MHABOLISM
SEE ALSO VITAMINS METABOLISM
** POlHL-0628518 0209 Cardiovascular-respiratory
physiology and biochemistry - Metabolic studies of isolated
lung cells (human, animals)
** POlHL-06308-18 0037 Mechanisms and therapy of
circulatory disease - Electrophysiology, blood flow, and ANS
in ventricular fibrillation (dogs)
POlHL-06312-17 0034 Surgical cardiology ■ Metabolic
factors in cardiac function-Creatine phosphate depletion
(animals)
Immunologic mechanisms in
Mediators of immune injury
P01HL-063I4-17 0046
cardiovascular disease
(human, mice)
POlHL-06314-17 0053
cardiovascular disease
'Excludes routine methodotegy OR cavers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
Immunologic mechanisms in
Cellular functions controlled by
cyclic GMP (human, mice, guinea pigs)
POlHL-06314-17 0064 Immunologic mechanisms in
cardiovascular disease - Diabetic vascular disease (human,
rats, mice)
POlHL-06664-17 0040 Cardiopulmonary function in
remediable vascular disease - The coupling of ion transport
to metabolism (toads)
POlHL-07896-15 0033 Environmental biomedical research
program - Breathing mechanism in birds
POlHL-08805-15 0047 Regulation of ventilation and
pulmonary circulation - Extracranial metabolic control of
ventilation (dogs, goats)
POlHL-08899-14 0012 Tolerance to respiratory gases in
health and disease - High oxygen for normal brain
metabolism and circulation in man
POlHL-08899-14 0013 Tolerance to respiratory gases in
health and disease - Oxygen and carbon dioxide effects
upon human brain metabolism
POlHL-08899-14 0027 Tolerance to respiratory gases in
health and disease - Effects of high oxygen pressures on
ethanol metabolism (human)
POlHL-08899-14 0035 Tolerance to respiratory gases in
health and disease - Simulation of the increased
metabolism of exercise (dogs)
POlHL-08899-14 0051 Tolerance to respiratory gases in
health and disease - Oxygen effects upon isolated retinal
metabolism (rabbits, monkeys)
POlHL-10342-13 0019 The integrated function of
respiration and circulation - Cerebral circulation and
metabolism (dogs)
(contd)
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
POIHI 10J4.' 13 002b The inl«£i«ted tundioii ot
laspiiation ind cifculalion Pulmoiiaiy gas Mchange and
metabolism (human, dogs, shgep)
POIHL 10436 13 0008 A multidisciplinary study ot
congenital heart disease Physiologic consequences ot
chronic hyponemia (human)
POIHI 11310 12 0063 Mechanisms ot catdiovasculat
disease Myocardial function, metabolism and cellular
integrity atter heart surgery (dogs)
POIHL 11310 12 0067 Mechanisms ot cardiovascular
disease Cardiac perlormance with measured
hemodynamic variables (human)
ROIHL 13921 07 The lung as a metabolic organ (animals)
ROIHL 1446607 Lung metabolism Enzymes in the
pulmonary circulation (human, animals)
' ROIHL 14461 08 Cardiac metabolism in heart tailute
(rats)
' POIHL 1519407 0018 Pathophysiology of
cardiopulmonary dysfunction Coronary cifculalion.
metabolic demand and vasodilatory reserve (human, dogs)
ROIHL 1551206 Drug treatment of stenosing primate
atherosclerosis (rabbits, monkeys)
■ POlHL-161 1806 0006 Study of emphysema Metabolism
of elastin (hamsters)
POIHL 1683304 0016 Hemoglobin and red cell system in
hemoglobinopathies - Calciumindiced membrane damage
in Hb SS disease (human, animals)
* ROlHL-1740303 Metabolic control of cardiac output
(dogs)
P01HL1741904 0001 Studies on mechanisms of
hemostasis - Structure and metabolism of fibrinogen
(human)
* P01HL1742105 0002 Regulation and exchange in the
microcirculation • Metabolic and myogenic blood flow
regulation in microcirculation (animals)
* ROlHL-17736-04 Metabolic change during cardiac
ischemia (rats, dogs)
R01HL17853-03 Peripheral circulation in heart failure
(animals)
ROlHL-1828003 Regulation of cardiac contractility and
metabolism (rats)
ROlHL-20566-02 Lactate metabolism in the lung (rats)
Coronary flow regulation by adenosine
Molecular basis of cholesterol
ROlHL-20782-01
(rats, dogs)
M POlHL-2094802
metabolism
POlHL-20948-02 0001 Molecular basis of cholesterol
metabolism - Biochemical and ultrastructural
characterization of LDL in human fibroblasts
POlHL-20948-02 0002 Molecular basis of cholesterol
metabolism ■ LDL pathway in cell lines with informative
properties other than fibroblasts
** POlHL-20948-02 0003 Molecular basis of cholesterol
metabolism - LDL pathway in vivo (human, rats, guinea
pigs)
POlHL-20948-02 0004 Molecular basis of cholesterol
metabolism - Genetic analysis of the LDL pathway (human)
♦* POlHL-20948-02 9001 Molecular basis of cholesterol
metabolism - Tissue culture core laboratory
** POlHL-20948-02 9002 Molecular basis of cholesterol
metabolism - Microscopy core laboratory
R23HL-21853-01 Lung metabolism and alveolo-capillary
permeability (rats)
** R23HL-2197301 Catecholamine metabolism and the heart
(human, guinea pigs)
** ROlHL-22088-02 Metabolic basis for diabetic
microangiopathy (cattle)
POlHL-22619-01 0008 Cellular mechanisms of heart
failure ■ Molecular mechanisms and differential contractile
responsiveness in VSM (dogs)
** POlHL-22633-01 0002 Cellular and molecular biology of
lipoprotein metabolism - Sterol metabolism in tissue
culture cells
" POlHL-22633-01 0003
lipoprotein metabolism
megakaryocytes (human, rabbits, guinea pigs)
METABOLISM, BIOTRANSFORMATION
SEE ALSO TOXICOLOGY, TOXICANT METABOLISM,
DETOXICATION
** POlHL-03174-23 0011 Mechanisms of acute vascular
reaction to injury - Mutagen metabolism by artery wall in
etiology of atherosclerosis (human, animals)
ROlHL-07878-16 Metabolism of neutral sterols (rats,
rabbits)
POlHL-12738-10 0001 Physiologic pharmacology and its
clinical applications ■ Clinical pharmacology of cardioactive
drugs (human)
ROlHL-17513-04 Role of PF-4 in detecting and promoting
thrombosis (human, primates)
ROlHL-18554-03 Taurine metabolism in mammalian heart
(rodents, cattle, swine)
POlHL-18574-03 0005 Lipoprotein methodology and
biomedical applications - Structure and function of
lipoproteins
** P01HL18574-03 0006 Lipoprotein methodology and
biomedical applications • Lipoprotein transformation,
lipolytic enzymes, diet and lipid lowering agents
P50HL-19170-02 0005 Harvard pulmonary SCOR-Chronic
diseases of the airways - Pulmonary toxicology of plastics
intermediates and pyrolysis products (animal)
ROlHL-21874-01 SRS-A-lts biosynthesis and action
Cellular and molecular biology of
- Sterol metabolism in platelets and
341
METABOLISM OF HEMOPROTEINS
Sff HfMOI'ROIflNS MflABOIISM
METABOLISM OF IRON
Stf IRON MIIAHOIISM
METABOLISM OF METALS
Stf MHAI MflABOIISM
METABOLISM STUDY SECTION
•* ROIHL 02033 23 Regulation of cholesterol esters in blood
and tissues (rat, cattle, human)
•* ROIHL 02965 22 Metabolism of plasma lipoproteins (rats,
chickens, human)
•• ROIHL 03734 18 Metabolism of arterial tissue in
atherosclerosis (rabbits)
** ROIHL 05062 18 Lipid metabolism in cultured cells
(human, rats, rabbits)
•* R01HL05360 19 Cholesterol biosynthesis and its control
in liver (rats)
•* R01HL06221 17 Composition and structure of plasma
lipoproteins (human, turkeys, baboons)
** ROIHL 0622218 Clinical and laboratory studies in lipid
metabolism (human, mammals, non-human)
•* R01HL0692416 Humoral and metabolic aspects of
cardiac function (mammals, non human, human)
** R01HL07878 16 Metabolism of neutral sterols (rats,
rabbits)
*• R01HL0850615 Lipemiacarbohydrate and glyceride
metabolism (human, rats)
** R01HL08634-15 Enzymic cholesterol synthesis (human,
rats, protozoa, yeast)
** ROlHL-09489-13 Myocardial lipid metabolism and
regulation (rats)
ROlHL-1001811
culture (rats)
ROIHL 1016013
ROlHL-10316-13
Effect of aging on beating heart cells in
Origins of atherosclerosis (human)
Structural studies on low density serum
lipoproteins (human)
ROlHL-10933-13 Fat metabolism and atherosclerosis
(rabbits, cattle, human, rats)
ROlHL-10940-13 Lipid transport (rabbits, cattle, chickens)
ROlHL-12085-10 Lipoproteincarbohydrate metabolism
(human, rats)
R01HL1286909 Arterial metabolism, diabetes and
atherogenesis (rats, rabbits)
R01HL1302809 Regulation of myocardial fatty acid
metabolism (rats)
ROlHL-13029-09 Metabolic regulation of sugar transport
Uptake and metabolism of lipids by the
Regulation of lipid metabolism in the
Lipid transport in avian species
Lecithin-Cholesterol acetyltransferase
Assays for peptides of lipoproteins
Secretion of plasma lipoproteins (rats)
Cardiovascular phosphoinositide
(pigeons, rats)
ROlHL-13302-09
liver (rats)
ROlHL-13405-09
lung (rats)
R01HL13625-06 Lipoprotein lipase and lipoprotein
removal (human, rats, bacteria)
ROlHL-14313-07 Apoproteins of triglyceride rich
lipoproteins (human, squirrel monkeys, rats)
ROlHL-14730-07 Fatty acid beta-oxidation in normal and
ischemic hearts (rabbits)
R01HL14990-07
(chickens)
ROlHL-1526306
(human, rabbits)
R01HL15308-07
(human)
ROlHL-1542706
R01HL-I5567-05
metabolism (rats)
■ ROlHL-15646-03 Lipid studies in vascular smooth muscle
cells (human, monkeys)
' ROlHL-15895-05 In vitro study of lipoproteins in vascular
disease (human, animals)
' ROlHL-15930-06 Hormonal control of lipid and lipoprotein
synthesis (rats)
' ROlHL-15949-05 Lipoprotein metabolism in relation to
atherosclerosis (human, baboons)
' R01HL46059-06 Structure and function of serum
lipoproteins (cattle, human)
■ ROlHL-16294-04 Effectors of cholesterol synthesis (rats)
' ROlHL-16364-04 Regulation of lipid biosynthesis and
transport (rats, swine, Xenopus)
* R01HL16577-04 Lipoprotein lipase chemistry and function
(rats, cattle, human)
* ROlHL-16796-05 Cholesterol regulation by HMG-CoA
reductase (rats, human)
* ROlHL-16807-02 Lipid structure of normal and
hypertipoproteins (human)
* ROlHL-17371-05 Regualtion of cholesteryl ester levels in
the aorta (swine)
* R01HL1746303 Composition and structure of plasma
lipoproteins (human, rabbits)
* ROlHL-17597-05 Role of plasma lipoproteins in
atherosclerosis (swine, human)
* ROlHL-1 78 18-05 Metabolism of cholesterol and cholesterol
in man (also rats, monkeys)
* R01HL-18094-04 Regulation of cholesterol biosynthesis
(rats)
* ROlHL-18206-04 Regulation of metabolism in oxygen
deficient hearts (rats)
'* ROlHL-182 19-04 Regulation of cholesterol metabolism
(rats)
• ROIHI lB/'58 04 Rejulslion of piolmn degradation in
heart (rats)
• ROIHL 18553 03 Membrane delect* in tamillal
hypercholesteremia (human)
• ROIHI 1868/03 Pathophysiology of genetic
hypcrtiiglycerinemias (human)
• ROIHI 18/05 03 Regulation of plasma triglyceride
metabolism (rats)
• ROIHL 188/8 03 Familial hypercholesteremia Studies of
tibroblasts (human)
'• ROIHL 1888/ 03 Hypolipidemic drugs Effects on FFA
albumin association (human, cattle)
'* ROIHL 19063 03 Cholesterol and lipoprotein metabolism
(rat hepatocytes)
'* ROIHL 19084 03 Structure and function of serum
lipoproteins (human)
"• ROIHL 19168 03 Biosynthesis of plasma lipoprotein (rats.
rabbits)
** ROIHL 191/503 Pituitary modulation of micro and macro
vascular disease (human, rats)
•* ROIHL 1922303 Control of cholesterogenesis in leukocytes
and liver (rats, human)
*• ROIHL 1925003 Mechanism of plasma cholesterol
esterification (human)
** ROIHL 19394-03 Biochemistry and regulation of taurine in
the heart (rats, guinea pigs, cats)
** ROlHL-20061 02 Serum lipoproteins and cell cholesterol
metabolism (rats, human)
** ROIHL 2030802 Regulation of myocardial acylcarnitine
transport (rats)
** ROlHL-20712-02 Characterization of the B proteins of
serum lipoproteins (human)
** ROlHL-20807 02 Detection of familial hypercholesterolemia
(human)
** R0)HL-20954-02 Hyperlipoproteinemia (rats, human)
** ROlHL-21381-02 Ammo acid metabolism in normal and
hypoxic myocardium (rabbits)
** R01HL-22474-01 Cholesterol metabolism and
atherosclerosis (rats, human, rabbits)
" ROlHL-22532-01 Inhibitors of cholesterol biosynthesis
(rats, mice, yeast)
** ROlHL-2256701 Validation of a cholesterol absorption
method in man
** ROlHL-2260701 Role of apolipoprotein E in lipoprotein
metabolism (human)
** ROlHL-22618-01 Role of apolipoproteins in
hypertriglyceridemia (human)
** ROlHL-22748-01 Effect of bile sequestration on VLDL
metabolism (human)
** ROlHL-22812-01 Regulation of hepatic production of HDL
(rats)
** R01HL-22967-01 Structure and function of heparin
releasable lipases (swine, human)
*• ROlHL-23945-06 Pathologic effects on cells of modified
lipoproteins (rats, human)
METAGENESIS
SEE BIOLOGY, LIFE CYCLE
METAL CHELATES
SEE METAL COMPLEXES
METAL COMPLEXES
SEE ALSO PORPHYRINS, METALLOPORPHYRINS
** R01HL12395-10 X-ray study of oxygen-carrying cobalt
Thermodynamic studies on model oxygen
complexes
ROlHL-15640-06
carriers
ROlHL-17739-04 Acute myocardial infarct scintigraphy
(human, dogs, rats)
ROlHL-18744-03 Preparation of radiopharmaceuticals from
drug analogs
** R01HL1883404 Metal-dependent complex formation in
blood coagulation (human, cattle)
ROlHL-19982-02 Blood coagulation -Protein-metal ionlipid
interactions
** ROlHL-20996-02 Structural and reactivity of iron and
cobalt complexes
METAL COMPLEXES, LIGANDS
ROlHL-01974-24 Ion-pump in the erythrocyte (rabbits,
guinea pigs)
ROlHL-05556-19 Proteins, lipoproteins-Structure and
reactivity (chicken, human, diving mammals)
*♦ POlHL-06314-17 0050 Immunologic mechanisms in
cardiovascular disease - Physiologic changes in
lymphocytes (human, mice)
R01HL07451-16 Hemoglobin S gelation and hemoglobin
allostery (human)
P01HL0789615 0052 Environmental biomedical research
program - Effects of hypoxia on cerebral function
ROlHL-08299-16 Molecular biology of hemerythrin and
hemocyanin (invertebrates)
POlHL-11310-12 0102 Mechanisms of cardiovascular
disease - Cardiac membrane and ion mobility (dogs)
ROlHL-12174-11 Ventilation/perfusion distribution in the
lung (human, mammals)
** ROlHL-1252410 Reaction of hemoglobin with ligands and
antibodies (human, carp)
ROlHL-12526-09 Raman spectra of heme proteins and
related molecules
R01HL1303508 Heart mitochondrial malate
dehydrogenase regulation
(contd)
•Excludes routine methodology OR covers only general projects which preclude
"Oriented signiticantly to above subject.
Indexing at the specific level.
M Grant has subprajects describing specific research aspects.
See Appendix for Investigator's name and grant number.
MET
R01HL13157-09 Molecular oxygen carriers-Synthesis,
structure, bonding
ROlHL-13164-07 Interaction of the alpha and beta chains
of human hemoglobin
ROlHL-13399-16 Heme protein structure and function
(human, horse, plants, bacteria)
Synthetic oxygen carriers
Coboglobins-Cobalt substituted myo- and
Reactions of oxygen with heme proteins
Physiochemistry and immunology of
Protein-lipid interaction (bacteria.
Investigation of hemoglobin S properties
** ROlHL-13412-17
** ROlHL-13531-06
hemoglobins
R01HL13581-11
ROlHL-13909-27
macromolecules
ROlHL-13921-07 The lung as a metabolic organ (animals)
POlHL-14388-07 0175 Regulation of the circulation in
pathological states - Functional studies of selected proteins
from cardiac muscle
** ROlHL-15284-06 Hemoglobin and myoglobin kinetic
studies (human, animals)
R01HL15460-06 Molecular adaptation-Hemoglobin
systems of fish (marine)
POlHL-1559605 0020 Coagulation, fibrinolysis,
hemostasis and hepatitis - Affinity chromatography
R01HL-16e27'Oe Xray and chemical studies of
metalloporphyrins
ROlHL'15640-06 Thermodynamic studies on model oxygen
carriers
ROIHL'16037'06 Molecular properties of cardiac
adrenergic receptors
R01HL'ie087'05 Structural and dynamic study of model
heme complexes (yeast)
** ROlHL-1609305 Functional properties of hemoglobin and
erythrocytes
R01HL1610105
models)
R01HL16375-04
(human)
R01HL-ie549-04 Cardiotonic steroid-NaK ATPase
interactions (cattle)
** ROlHL-16746-04 Design of ion-selective molecules
M POIHL 16833-04 Hemoglobin and red cell system in
hemoglobinopathies
" POlHL-16833-04 0001 Hemoglobin and red cell system in
hemoglobinopathies - Motility, association and ligand
binding in hemoglobin-Hydrogen exchange
POlHL-16833-04 0002 Hemoglobin and red cell system in
hemoglobinopathies - Polymerization and gel formation In
solutions of hemoglobin A and S (human)
P01HL-ie83304 0006 Hemoglobin and red cell system in
hemoglobinopathies Role of water In function of
hemoglobin and myoglobin (human)
P01HL1683304 0017 Hemoglobin and red cell system in
hemoglobinopathies - Sulfhydryl group blockade antisickling
effect (human)
" R01HL1749407 Mechanism of liqand binding to
hemoglobin (human)
ROlHL-17976-18 Chemical agents and heart glycolytic
enzymes (sheep)
ROlHL-1830904 Oxygen transport-Hemoglobins with
modified hemes (horse)
R01HL19129-04 Cardiac glycosides-Mechanisms of
cellular actions
ROlHL'19423-03 Catecholamine action on the heart (cats,
rats)
ROlHL-1948103 High-field NMR studies of respiratory
proteins (human, horse, fish, microbes)
ROlHL-19488'03 Picosecond laser studies of heme-
proteins
ROlHL-19721-03 Lung inflammation -Lysosomal proteases
and liposomes (human, rabbits)
POlHL-19737-02 0004 Cellular and molecular aspects of
respiratory physiology - Rapid reactions and erythrocyte
exchanges of blood during respiratory transport
POlHL-20984-02 0002 Cellular mechanisms in cardiac
hypertrophy - Thermodynamic, fluorescence, chemical
modification of hypertrophied heart myosin
ROlHL-2099602 Structural and reactivity of iron and
cobalt complexes
•• POlHL-2 1016-02 0005 Sickle cell anemia and other
hemoglobinopathies - Ligand kinetics in normal and Hb S
containing erythrocytes (human)
ROlHL-21329-02 Beta-receptor regulation and cardiac
sites of drug action (cat, guinea pig, rat)
ROlHL-21461-01
hemoproteins
ROlHL-2148301
of hemoglobin
ROlHL-21540-02 Specific inhibitors of coagulation and
fibrinolysis (rats, rabbits, dogs)
ROlHL-21543-02 Structure-function relation of blood
clotting proteins (rabbits)
ROlHL-22265-02 Isozymes of heart glutamate aspartate
transaminase (swine, ducks)
R23HL-22490-01 Neurotransmitter receptors of cultured
heart cells
POlHL-22619-01 0004 Cellular mechanisms of heart
failure - Mechanism of action of Na, K-ATPase (sheep,
cattle)
ROlHL-22780-01 Factors modifying the reaction properties
of HgS (human)
METAL COMPLIXIS, LIOANDS, CHGLATINO
AGENTS
SEE ALSO SULFUR AMINO ACIDS, PENICILUMINE
Heme group protein interactions in
Electronic, thermodynamic and kinetics
342
ROlHL-16746-04 Design of ion-selective molecules
ROlHL-17739-04 Acute myocardial infarct scintigraphy
(human, dogs, rats)
** ROlHL-17794-03 Chelating agents as blood substitutes
" ROlHL-19127-03 Synthesis of molecules for myocardial
imaging (rats)
ROlHL-19419-03 Cellular interactions with foreign
materials (mammals)
ROlHL-19491-03 Mechanism of Iron storage and
mobilization by ferritin (horse)
** ROlHL-21273-02 Fibrinogen labeling with radiometals
** ROlHL-23120-01 Chelating agents as blood substitutes
METAL DISORDERS AND IMBALANCES
SEE ALSO BODY FLUID BAUNCE, IONIC, HYPERKALEMIA
SEE ALSO BODY FLUID BAUNCE, IONIC, HYPOKALEMIA
SEE ALSO BODY FLUID BAUNCE. IONIC. HYPONATREMIA
SEE ALSO IRON DISORDERS AND IMBAUNCES
** ROlHL-11614-11 Trace elements in nutrition (chickens,
rats, human)
P50HL-14214-07 0028 Newborn lung center for hyaline
membrane disease - Relationship of trace metals to
respiratory failure (dog, sheep, human)
** P60HL-16008-06 0015 Wayne State University
comprehensive sickle cell center - Trace elements in sickle
cell disease (human)
METAL DISORDERS AND IMBALANCES,
HYPOCUPREMIA
SEE ALSO METABOLIC DISORDERS INBORN, KINKY HAIR
SYNDROME
** ROlHL-12561-11 Cardiovascular studies on copper
deficiency (swine)
P50HL- 142 14-07 0028 Newborn lung center for hyaline
membrane disease - Relationship of trace metals to
respiratory failure (dog, sheep, human)
ROlHL-189 18-03 Characterization of lung elastins (rat,
rabbit, chicken. Rhesus)
METAL DISORDERS AND IMBALANCES,
MAGNESIUM DEFICIENCY
ROIHL 2312801 Cardiac contractility-Ischemia and
hypoxia (rabbits, rats)
METAL METABOLISM
SEE ALSO IRON MHABOLISM
** R01HL1963302 Pathogenesis and pharmacology of lung
fibrosis (rats, rabbits)
METAL METABOLISM DISORDERS
SEE METAL DISORDERS AND IMBAUNCES
METALLIC COMPOUNDS ORGANIC
SEE ALSO METAL COMPLEXES
SEE ALSO METALLOPROTEINS
SEE ALSO PORPHYRINS, METALLOPORPHYRINS
SEE ALSO PORPHYROPROTEINS, METALLOPORPHYROPROTEINS
ROlHL-20996-02 Structural and reactivity of iron and
cobalt complexes
METALLOBORANES
SEE METALS. BORON COMPOUNDS, BORANES
METALLOENZYMES
SEE ENZYMES, METALLOENZYMES
METALLOPORPHYRINS
SEE PORPHYRINS, METALLOPORPHYRINS
METALLOPORPHYROPROTEINS
SEE PORPHYROPROTEINS. METALLOPORPHYROPROTEINS
METALLOPROTEINS
SEE ALSO ALBUMINS. CONALBUMIN
SEE ALSO ENZYMES. METALLOENZYMES
SEE ALSO METAL METABOLISM
SEE ALSO PORPHYROPROTEINS, METALLOPORPHYROPROTEINS
** ROlHL-13399-16 Heme protein structure and function
(human, horse, plants, bacteria)
** ROlHL-13652-08
(mushroom)
ROlHL-21461-01
hemoproteins
Synthesis of labeled hemes for protein
Metal sites in metalloproteins
Heme group protein interactions in
ROlHL-22252-01
NMR studies
METALLOPROTEINS, CERULOPLASMIN
ROlHL-16601-05 Structure and function of blood proteins
(human, cattle)
METALLOPROTEINS, CYTOCUPREINS
** POlHL-07896-15 0039 Environmental biomedical research
program - Development of resistance to lethal effects of
oxygen (rats)
POlHL-07896-15 0047 Environmental biomedical research
program - Pulmonary oxygen toxicity (chickens, rabbits)
ROlHL-13399-16 Heme protein structure and function
(human, horse, plants, bacteria)
ROlHL'14663-07 Pulmonary oxygen toxicity In newborn
lung (human, mice)
P50HL-15O61-07 0009 Response of lung to Injury -
Alveolar macrophages (human, rabbits)
P01HL-16748-0S 0004 Cellular and immunological basis
of pulmonary diseases ■ Cellular and Immunological
processes In pulmonary defense systems
'Exclude! routine methodokigy OR coven only iineral projectt which preclude Indexing at the specific level.
"Oriented ilgnlf Icintly to atwva iub|act.
MET
ROlHL-17719-03 Lung injury, substrate utilization, oxygen
toxicity (rats, rabbits, dogs)
P50HL-18828-03 0008 Specielized center of research in
thrombosis - Biochemistry. physiology-Platelets and
subcellular platelet particles (human)
ROlHL-19532-01 Oxygen toxicity in the red cell (human)
ROlHL-19721-03 Lung inflammation-Lysosomal proteases
and liposomes (human, rabbits)
ROlHL-19779-03 Biochemical basis of oxygen damage to
lung cells (guinea pigs, rats)
ROlHL-20352-02 Defenses of lung cells against oxygen
toxicity (human, animals)
ROlHL-20366-03 Protein turnover and amino acid
transport by lung (rats)
** ROlHL-21115-01 Prevention of 02 toxicity with superoxide
dismutase (rats)
METALLOPROTEINS, FERREDOXIN
ROlHL-13399-16 Heme protein structure and function
(human, horse, plants, bacteria)
ROlHL-13619-09 Microsomal electron transport in liver
and heart (human, mammals)
ROlHL-13652 08 Metal sites In metalloproteins
(mushroom)
METALLOPROTEINS, FERRITIN
POlHL-08805-15 0048 Regulation of ventilation and
pulmonary circulation - Permeability of alveolo-Capillary
membrane in normal pulmonary hypertensive lung
POlHL-09011-15 0015 A research and resource program
in blood - Regulation of synthesis and transport of diverse
proteins in liver (rats)
** ROlHL-11511-10 Structure of ferritin and Its role in iron
metabolism (horse, rats, human)
" ROlHL-19491-03 Mechanism of iron storage and
mobilization by ferritin (horse)
** ROlHL-20141-02 Biochemical approaches to management
of iron overload (human, sheep, dogs)
POlHL-22602-01 0002 Pathophysiology of the
endothelium - Molecular charge and endothelial
permeability (rats, mice)
METALLOPROTEINS, HEMERYTHRIN
** ROlHL-08299-16 Molecular biology of hemerythrin and
hemocyanin (invertebrates)
** ROlHL-17828-04 Kinetic studies of hemerythrin reactions
(marine worms)
METAUOPROTEINS, HEMOCYANIN
" ROlHL-08299-16 Molecular biology of hemerythrin and
hemocyanin (invertebrates)
R01HL-131S7-09 Molecular oxygen carriers-Synthesis.
structure, bonding
ROlHL-22325-01 Thermodynamics in respiratory protein
binding (human, trout)
METALLOPROTEINS, TRANSFERRIN
ROlHL-0624218 Kinetic studies of blood (human)
ROlHL-07449-17 Formation and survival of red blood cells
(human)
R01HL13399-16 Heme protein structure and function
(human, horse, plants, bacteria)
** ROIHL- 186 19-03 Transferrin iron binding and transport
properties (chicken, rabbit, human)
** ROlHL-1913204 Role of zinc transferrin in lymphocyte
transformation (human)
P50HL-19155-02 0002 Pathophysiology of pulmonary
edema ■ Non-invasive measurement of protein turnover In
human lung (also sheep)
** ROlHL-20141-02 Biochemical approaches to management
of iron overload (human, sheep, dogs)
** ROlHL-2 11 70-01 Molecular structure of human serum
transferrin
METALS
ROlHL-20037-02 Left ventricular-aortic bypass and
composite prosthesis (sheep, swine, cattle)
POlHL-22619-01 0005 Cellular mechanisms of heart
failure - Molecular mechanism of regulation of cardiac
muscle contraction (cattle)
METALS, ALKALI METALS
SEE ALSO LITHIUM
SEE ALSO POTASSIUM
SEE ALSO SODIUM
ROlHL-16474-05 Antibiotic-ion interactions (model
membranes)
METALS, ALKALI METALS, CESIUM
ROlHL-21 136-02 Ion activities and transport in cardiac
muscle cells (sheep)
METALS, ALKALI METALS, RUBIDIUM
SEE ALSO RADIOISOTOPES. RUBIDIUM
ROlHL-21136-02 Ion activities and transport In cardiac
muscle cells (sheep)
METALS, ALKALINE EARTH METALS
SEE ALSO CALCIUM
ROlHL-16474-05 Antibiotic-ion Interactions (model
membranes)
METALS, ALKALINE EARTH METALS, BARIUM
POlHL-14388-07 0178 Regulation of the circulation In
pathological states - Structural and functional
consequences of denervation (rats)
(contd)
M Grant has subprojects describing specific research ispecti.
See Appendix for Investigator's name and grant number.
MET
ROIHI 16746 04 Design of ion sal«clive moleculej
ROIHl 18912 03 Mechanics of tiesrt muscle contraction
(cats, dogs)
ROIHL 21670 01 AntiaiTliyttimic studies on 2 substituted
aminoindenes (dogs)
METALS, ALKALINE EARTH METALS, BERYLUUM
SEE ALSO METALS POISONING, BERYLLIOSIS
PSOHL 1421207 0013 Correlated studies ol pulmonary
libcosis Mechanism ol beryllium pathogenicity in the lung
(human, rabbit, guinea pig)
METALS, ALKALINE EARTH METALS,
MAGNESIUM
SEE ALSO METAL DISORDERS AND IMBAUNCES. MAGNESIUM
DEFICIENCY
R01HL01974 24 Ion pump in the erythrocyte (rabbits,
guinea pigs)
P01HL0631217 0051 Surgical cardiology Diuretic
therapy on myocardial electrolyte composition and water
content (human)
ROIHL 09364 14 Ion transport by heart mitochondria
(cattle, rat. rabbit)
ROIHL'10503 13 Cardiac ion transport and ultrastructure
(rats, guinea pigs, rabbits)
** ROIHL'12774'08 Ionic coupling in activation of cardiac
muscle (frogs, guinea pigs)
R01HL13193-09 Pathophysiology of post-traumatic and
shock states (rodents, dogs)
R01HL14020-06 Characterization of myosin from blood
platelets (rabbit)
P01HL1438807 0179 Regulation of the circulation in
pathological states - Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
** POlHL-1438807 0192 Regulation of the circulation in
pathological states • Renal tubular secretion of magnesium
(rats)
R01HL15692-07 Force and speed m sKeletal and cardiac
muscle
P01HL1583506 0001 Study of muscles related to heart
disease Control of contraction-relaxation of heart and
muscle (rabbits, chickens)
POlHL-15835-06 0021 Study of muscles related to heart
disease - Fast kinetic studies in muscle subcellular
organelles (animals)
R01HL16010-16 Cellular basis of cardiac contractility
(frogs)
R01HL-ie746-04 Design of ion-selective molecules
POlHL-16769-05 0002 Pathobiologic and host defense
reactions in the lung - Pathogenesis of complement
dependent injury to the lungs (rabbits)
P60HL'17269-04 0019 National heart and blood vessel
research and demonstration center - Sarcoplasmic
reticulum (dog. rabbit, hamster, cat)
R01HL181 79-03 Heart, platelet, and muscle myosins and
actomyosins (cattle)
ROlHL-18737-03 Human erythrocyte membrane structure
ROlHL-19485-03 Calcium uptake by normal and failed
cardiac ATPase (dogs)
R01HL-19673-03 Surgical aspects of shock and hypoxia
(dogs, monkeys, rats)
ROlHL-20079-02 0001 Thromboresistant material - Active
and passive thromboresistant surfaces
ROlHL-20262-02 Cardiac glycosides and the mechanism
of the sodium-potassium pump
ROlHL-20464-01 Regulation of cardiac and skeletal
muscle contraction (mammals)
** POlHL-20592-02 0003 Cell biology of cardiac and
skeletal muscle - Cellular magnesium and anion activities
in ion-specific m icroelectrodes (frogs)
POlHL-20592-02 0012 Cell biology of cardiac and
skeletal muscle - Contractile properties of skinned muscle
Calcium regulation and hypertension
fibers (frogs)
ROlHL-21030-01
(rats)
ROlHL-21922-01 Transient currents induced by
strophanthidin in the heart
ROlHL-22039-02 Ion transport in cardiac muscle (dogs,
Modulation of calcium control of cardiac
Regulation of tension and active state in
rodents, cattle)
ROlHL-22231-02
myofibrils (rats)
ROlHL-22401-01
the heart
ROlHL-23392-01 Membrane binding and transport of
calcium and potassium ionophores
R01HL-23615-0I Biochemistry of contractile proteins
(chicken, rabbit)
ROlHL-23994-01 Biochemical properties of human cardiac
myosin
METALS, ALLOYS
POlHL-11414-11 0027 Thrombosis and atherosclerosis
program ■ Thermal memory wire filter to prevent pulmonary
embolism (human, dogs)
** ROlHL-20554-02 Memory-alloyfilters for venous emboli
(dogs)
MCTALS, BORON COMPOUNDS, BORANES
ROlHL-22040-01 Regulation of lysyi-cross-llnking In
vtscular tisiui (rats, turkeys)
343
METALS, DIVALENT METALS
POIHI 06314 17 OObl Immunologic mechanisms in
cardiovascular disease Antigens in cardiovascular disease
(human)
ROIHL 164/4 05 Antibiotic ion interactions (model
membranes)
ROIHL 16746 04 Design of ion selective molecules
POIHL 17430 05 0005 Control of coagulation The
activation ol prothrombin (human, cattle, dogs)
ROIHL 20544 02 Integrated regulation of myocardial
energy metabolism (rats, guinea pigs)
METALS, HEAVY METALS
SEE ALSO CHEMICAL REACTIONS. SUBSTITUTION.
ISOMORPHOUS
SEE ALSO IRON
SEE ALSO METALS. RARE EARTHS
SEE ALSO RADIOISOTOPES, TECHNETIUM
ROIHL 12528 10 NMR relaxation of liquid crystal systems
METALS, HEAVY METALS, CADMIUM
P01HL08974 14 0005 Natural and experimental
atherosclerosis Atherosclerosis, coronary heart disease
and sudden death (human)
ROlHL-149 13-06 Hypertension -Genetic influence of kidney
(rats)
** ROIHL 16674-05 Airborne metals and lung permeability
(bullfrogs, rats)
P50HL-19362-02 0006 A/S SCOR -Atherosclerosis in
nonhuman primates Effects of cigarette smoking on
atherosclerosis (baboon)
ROIHL 19668-03 Biochemistry of lung connective tissue
(rats)
POlHL-197 17-02 0008 Response of the lung to injury -
Experimental models of lung disease
POlHL-20994 02 0003 Dynamics of neutrophil elastase in
the lung - Neutrophil elastase flux in models of lung
disease (dogs)
** ROlHL-22603-01 Trace metals, vascular activity and
hypertension (rats)
METALS, HEAVY METALS, CHROMIUM
SEE ALSO RADIOISOTOPES, CHROMIUM
ROlHL-134 12-17 Synthetic oxygen carriers
METALS, HEAVY METALS, COBALT
SEE ALSO VITAMIN 812
** ROlHL-12395-10 X-ray study of oxygen-carrying cobalt
complexes
ROlHL-131 57-09 Molecular oxygen carriers-Synthesis,
structure, bonding
** ROlHL-13412-17 Synthetic oxygen carriers
ROlHL-13531-06 Coboglobins -Cobalt substituted myo- and
hemoglobins
R01HL15640-06
carriers
** ROlHL-20996-02
cobalt complexes
ROlHL-21461-01
hemoproteins
R01HL-23736-04
synthesis (monkeys)
METALS, HEAVY METALS, COPPER
SEE ALSO METAL DISORDERS AND IMBALANCES,
HYPOCUPREMIA
SEE ALSO METALLOPROTEINS, CERULOPLASMIN
SEE ALSO METALLOPROTEINS, CYTOCUPREINS
SEE ALSO METALLOPROTEINS. HEMOCYANIN
R01HL-10503-13 Cardiac ion transport and ultrastructure
(rats, guinea pigs, rabbits)
ROlHL-11614-11 Trace elements in nutrition (chickens,
rats, human)
ROlHL-13399-16 Heme protein structure and function
(human, horse, plants, bacteria)
ROlHL-15980-06 Reactions of hemoproteins and oxygen
(cattle)
P60HL-16008-06 0015 Wayne State University
comprehensive sickle cell center - Trace elements in sickle
cell disease (human)
ROIHL- 166 86-04 Properties of cytochrome oxidase (cattle,
bacteria)
R01HL-18095-04 Human dopamine-beta-hydroxylase (also
cattle)
POlHL-18708-03 0010 Oxygen, energy and contractility in
cardiac tissue - Tissue oxygen utilization (rats, dogs)
ROlHL-187 12-03 Iron deficiency-hyperlipidemla in
development (rats)
ROlHL-19633-02 Pathogenesis and pharmacology of lung
fibrosis (rats, rabbits)
ROlHL-20996-02 Structural and reactivity of iron and
cobalt complexes
** ROlHL-22446-01 Chemical and functional studies of low
copper in lung (pigs)
METALS, HEAVY METALS, LEAD
SEE ALSO METALS POISONING, LEAD POISONING
ROlHL'16746-04 Design of Ion-selective molecules
P5DHL-19362-02 0006 A/S SCOR-Atherosclerosis in
nonhuman primates - Effects of cigarette smoking on
atherosclerosis (baboon)
Thermodynamic studies on model oxygen
Structural and reactivity of iron and
Heme group protein interactions in
Sickle cell anemia and hemoglobin
MET
METALS, HEAVY METALS, MANGANESE
POIHL 11351 I? OOn Cellular and molecular
mechanisms ol myocardial lunction Ion exchange in the
perfused septum high resolution technique (rabbits, rats)
POIHI 14985 07 0012 Adaptation to hypoxia Direct
effect of hypoxia on pulmonary vascular smooth muscle
(rats, dogs)
POIHL 15194 07 0004 Pathophysiology of
cardiopulmonary dysfunction Specialized electrophysiology
libers Electrogenic basis ol glycosides (mammals)
ROIHL 16010 16 Cellular basis ol cardiac contractility
(Irogs)
ROIHL 1613505 Mechanisms of cardiac aulorhythmicity
(dogs, bats)
ROIHL 21461 01 Heme group protein interactions in
hemoproteins
METALS, HEAVY METALS, MERCURY
SEE ALSO METALS POISONING. MERCURY POISONING
ROIHL 1667405
(bullfrogs, rats)
ROIHL 16746-04
ROIHL 19463-02
(rats)
Airborne metals and lung permeability
Design of lon-selective molecules
Pathophysiology of acute renal failure
METALS, HEAVY METALS, NICKEL
ROlHL-2 1120-02 Membrane dynamics in alveolar
macrophages (rabbits)
METALS, HEAVY METALS, RUTHENIUM
ROIHL 14127-16 Methemoglobinemia and antihypertensive
drugs (cats. mice, rats)
METALS, HEAVY METALS, TANTALUM
POlHL-1 1310-12 0055 Mechanisms of cardiovascular
disease Ventricular pressure-volume after intracardiac
surgery (human)
" P50HL 19156-02 0003 Pulmonary SCOR -Chronic diseases
of airways Powdered tantalum to study airway morphology
and mucociliary clearance (human)
METALS, HEAVY METALS, ZINC
** N01HB-72916-02 Crisis and pain symptom prophylaxis by
oral zinc therapy (human)
POlHL-08974-14 0005 Natural and experimental
atherosclerosis Atherosclerosis, coronary heart disease
and sudden death (human)
ROIHL 11614-11 Trace elements in nutrition (chickens,
rats, human)
ROlHL-13636-08 Effects of pharmacologic agents on heart
metabolism (human, rodents)
P50HL- 142 14-07 0028 Newborn lung center for hyaline
membrane disease Relationship of trace metals to
respiratory failure (dog, sheep, human)
** P60HL-16008-06 0014 Wayne State University
comprehensive sickle cell center - Zinc and red blood cell
metabolism in sickle cell anemia (rats, human)
" P60HL-16008-06 0015 Wayne State University
comprehensive sickle cell center - Trace elements in sickle
cell disease (human)
ROlHL-16674-05 Airborne metals and lung permeability
(bullfrogs, rats)
POIHL- 16833-04 0016 Hemoglobin and red cell system in
hemoglobinopathies - Calcium-indiced membrane damage
in Mb SS disease (human, animals)
ROlHL-18712-03 Iron deficiency-hyperlipidemia in
development (rats)
ROlHL-18737-03 Human erythrocyte membrane structure
ROlHL-18905-04 Acquisition of native conformation of
proteins (human, cattle)
" ROlHL-19132-04 Role of zinc transferrin in lymphocyte
transformation (human)
P50HL-19362-02 0006 A/S SCOR-Atherosclerosis in
nonhuman primates - Effects of cigarette smoking on
atherosclerosis (baboon)
** ROlHL-19633-02 Pathogenesis and pharmacology of lung
fibrosis (rats, rabbits)
ROlHL-19720-03 Evaluation of anti-fibrotic agents in
pulmonary fibrosis (rats)
ROlHL-2 11 20-02 Membrane dynamics in alveolar
macrophages (rabbits)
ROlHL-22446-01 Chemical and functional studies of low
copper in lung (pigs)
METALS, METALLOIDS, SELENIUM
ROlHL-13619-09 Microsomal electron transport in liver
and heart (human, mammals)
ROlHL-16330-06 Aging-tissue injury and repair (rats)
ROlHL-16674-05 Airborne metals and lung permeability
(bullfrogs, rats)
METALS, RARE EARTHS
R01HL-14508-10 Structure and function of respiratory
hemoproteins
ROlHL-18834-04 Metal-dependent complex formation in
blood coagulation (human, cattle)
ROlHL-19282-03 Regulation of the activation of human
factor X
ROlHL-2 1543-02 Structure-function relation of blood
clotting proteins (rabbits)
NOlHV-72931-02 Non-invasive detection of atherosclerotic
lesions (human, dogs)
(contd)
tidudM routine mathodokigy OR covers only general pniecti which preclude Indexing at the specific level.
"Ortentad significantly to above tubjact.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
MET
METALS, RARE EARTHS, LANTHANUM
POlHL-11351-12 0011 Cellular and molecular
mechanisms of myocardial function ■ Comparative
contractile tissue studies (animals)
POlHL-11351-12 0013 Cellular and molecular
mecfianisms of myocardial function - Ion exchange in the
perfused septum high-resolution technique (rabbits, rats)
POlHL-14985-07 0012 Adaptation to hypoxia ■ Direct
effect of hypoxia on pulmonary vascular smooth muscle
(rats, dogs)
METALS POISONING
SEE ALSO METAL COMPLEXES, LIGANDS, CHELATING AGENTS
** P50HL-1506107 0002 Response of lung to injury -
Oxidative metabolism, phospholipid synthesis, and response
to toxins (rats)
METALS POISONING, BERYLLIOSIS
•* P50HL-14212-07 0013 Correlated studies of pulmonary
fibrosis - Mechanism of beryllium pathogenicity in the lung
(human, rabbit, guinea pig)
POlHL-19717-02 0038 Response of the lung to injury -
Interstitial lung disease--Clinlcal, pathologic and
epidemiologic
METALS POISONING, LEAD POISONING
ROlHL-18163-04 Red cell membrane effects due to
oxidizing agents
ROlHL-21817-01 Catecholamines, blood pressure and
circulation
METALS POISONING, MERCURY POISONING
ROlHL-1778103 Hypertension, kidney disease and renal
lymph (dogs, rats)
R01HL19668-03 Biochemistry of lung connective tissue
(rats)
METANEPHRINE
SEE PHENYLALKYUMINES. CATECHOLAMINES,
METANEPHRINE
METAPLASIA
SEE GROWTH ABNORMAL. METAPLASIA
METASTASIS
SEE NEOPLASTIC GROWTH. NEOPLASMS METASTASIS
METEOROLOGY
SEE ENVIRONMENT, ATMOSPHERE (WEATHER)
METHACHOLINE
SEE CHOLINE. METHACHOLINE
METHACRYLATES
SEE PLASTICS. ACRYLIC POLYMERS. METHACRYLATES
METHANE
SEE ALKANES. METHANE
METHANOL
SEE ALCOHOLS, METHANOL
METHEMOGLOBIN
SEE HEMOPROTEINS, HEMOGLOBIN. METHEMOGLOBIN
METHEMOGLOBINEMIA
SEE HEMOPROTEINS. METHEMOGLOBINEMIA
METHIONINE
SEE SULFUR AMINO ACIDS, METHIONINE
METHODOLOGY, ANALYTICAL CHEMISTRY
SEE CHEMISTRY. ANALYTICAL METHODS*
METHOPYRAPONE
SEE PYRIDINES. METYRAPONE
METHOTREXATE
SEE FOLIC ACID ANTAGONISTS, METHOTREXATE
METHOXAMINE
SEE PHENYLALKYUMINES, METHOXAMINE
METHOXYFLURANE
SEE HALOETHERS, METHOXYFLURANE
METHOXYINDOLES
SEE BENZOPYRROLES, METHOXYINDOLES
METHYLATED RNA
SEE NUCLEIC ACIDS, METHYLATED RNA
METHYLATiON
SEE ALKYL (GROUPS), METHYLATION
3-METHYLBUTYL NITRITE
SEE NITRITES. AMYL NITRITE
METHYLCHOLANTHRENE
SEE CYCLICS, CARBOPOLYCYCLICS, METHYLCHOLANTHRENE
ALPHA-METHYL DOPA
SEE CYCLIC AMINO ACIDS, DOPA, ALPHA-METHYL DOPA
1,2-METHYLENEDIOXYBENZENES
SEE 1,3-BENZODIOXOLES
1,2-METHYLENEDIOXYPHENYL COMPOUNDS
SEE 1,3-BENZODIOXOLES
344
O-METHYL GLUCOSE
SEE HEXOSES, GLUCOSE, O-METHYL GLUCOSE
O-METHYL INDOLES
SEE BENZOPYRROLES, METHOXYINDOLES
METHYLMALONYL-COA SYNTHETASE
SEE CARBON-CARBON LIGASES, PROPIONYL COA
CARBOXYUSE (ATP-HYDROLYZING)
N-METHYLNICOTINAMIDE
SEE PYRIDINAMIDES, NICOTINAMIDE, NMETHYL-
METHYLPREDNISOLONE
SEE ADRENAL CORTEX HORMONES ANALOGS,
METHYLPREDNISOLONE
METHYLSULFOXIDE
SEE SULFOXIDES, DIMETHYL SULFOXIDE
N-METHYL TRANSFERASES
SEE TRANSMETHYLASES. N-METHYL TRANSFERASES
METHYSERGIDE
SEE ALKALOIDS, ERGOT, METHYSERGIDE
METOPYRONE
SEE PYRIDINES, METYRAPONE
METYRAPONE
SEE PYRIDINES, METYRAPONE
MEVALONATE:NADP OXIDOREDUCTASE
SEE OXIDOREDUCTASES, HMG-COENZYME A REDUCTASE
MEVALONIC ACID
SEE FAHY ACIDS, MEVALONIC ACID
MEXICAN-AMERICANS
SEE SOCIAL GROUPS, ETHNIC, AMERICANS, MEXICAN-
AMERICANS
MICE (LABORATORY)
SEE MAMMALS, RODENTS, MYOMORPHA. MICE
(LABORATORY)*
MICELLE FORMATION (CHEMISTRY)
SEE CHEMICAL AGGREGATES, MICELLE FORMATION
MICROANGIOGRAPHY
SEE CARDIOVASCUUR VISUALIZATION, MICROANGIOGRAPHY*
MICR08ACTERIUM MULTIFORME
SEE CHLAMYDIA, PSITTACOSIS AGENT
MICROBIAL ANTITOXINS
SEE IMMUNOLOGY. ANTITOXINS
MICROBIAL CHEMISTRY STUDY SECTION
** ROlHL-22981-17 Membrane-associated functions in
microorganisms (bacteria, protozoa)
MICROBIAL CULTURE
SEE GROWTH MICROORGANISMS. MICROBIAL CULTURE
MICROBIAL DISEASES (GENERAL)
SEE COMMUNICABLE DISEASES (GENERAL)
MICROBIAL GENETICS
SEE GENETICS. MICROBIAL
MICROBIAL IDENTIFICATION AND
CLASSIFICATION (TECHNIQUES)
** P50HL-15389-07 0019 Pulmonary SCOR-Hypersensitivity
pneumonitis - Microbiology core (human, animal)
P50HL-191 71-02 0001 Pulmonary SCOR-Lung injury by
childhood infections - Longitudinal study-Respiratory
infections and lung growth in normal children
** P50HL-19171-02 0012 Pulmonary SCOR-Lung injury by
childhood infections - Laboratory support core
P50HL-19362-02 0009 A/S SCOR-Atherosclerosis in
nonhuman primates ■ Cholesterol metabolism and
intestinal microflora (baboon)
** P60HL-23282-01 0004 Comprehensive hospital/community
sickle cell center - Bacterial, viral and mycoplasmal
infections and sickle cell disease complications
MICROBIAL IDENTIFICATION AND
CLASSIFICATION, SEROTYPING
SEE ALSO IMMUNITY, CROSS IMMUNITY
ROlHL-203 14-02 Host defense against S pheumoniae in
sickle cell disease (human)
MICROBIAL IDENTIFICATION AND
CLASSIFICATION, VIRAL TYPING AND
IDENTIFICATION
POlHL-1 13 10-12 0100 Mechanisms of cardiovascular
disease ■ Structure and replication of arenavirus and
Bunyamweraviruses
P50HL-141 36-07 0003 Pulmonary SCOR -Airways
obstructive diseases - Acute pediatric respiratory disease
and COLD
P50HL-15389-07 0019 Pulmonary SCOR-Hypersensitivity
pneumonitis - Microbiology core (human, animal)
ROlHL-16246-06 Immunologic studies in
postpericardiotomy syndrome (human)
P50HL-191 57-02 0011 Studies in cystic fibrosis and
bronchiolitis - Pathogenesis of bronchiolitis (children)
MIG
P60HL-23282-01 0004 Comprehensive hospital/community
sickle cell center - Bacterial, viral and mycoplasmal
infections and sickle cell disease complications
MICROBIAL IMMUNOLOGY
SEE IMMUNOLOGY, MICROBIAL
MICROBIAL ORAL FLORA
SEE ALSO BACTERIA, MICROCOCCACEAE, STAPHYLOCOCCUS*
SEE ALSO BACTERIA, STREPTOCOCCACEAE,
STREPTOCOCCUS*
R01HL-20963-01 Experimental lung abscess (rabbits)
MICROBIAL RESISTANCE TO DRUGS
SEE DRUGS RESISTANCE, MICROBIAL
MICROCIRCULATION
SEE CARDIOVASCUUR SYSTEM, MICROCIRCULATION
MICROELECTRODES
SEE ELECTRODES, MICROELECTRODES*
MICROFILAMENTS
SEE CELL COMPONENTS, MICROFIUMENTS
MICROINJECTIONS
SEE DOSAGE AND ROUTE, INJECTIONS, MICROINJECTIONS
MICROORGANISMS
SEE ALSO CHUMYDIA
SEE ALSO FUNGI*
SEE ALSO GENETICS, MICROBIAL
SEE ALSO MICROBIAL ORAL FLORA
SEE ALSO VIRUSES
** POlHL-08214-15 0023 Chemical and biological properties
of lipids - Lipids in microorganisms and cell cultures
(hamsters, mosquitoes)
** POlHL-08214-15 0048 Chemical and biological properties
of lipids - Lipids in microorganisms and plants
** ROlHL-22981-17 Membrane-associated functions in
microorganisms (bacteria, protozoa)
MICROORGANISMS, AEROBES
SEE ALSO BACTERIA, HALOBACTERIACEAE*
SEE ALSO BACTERIA, STREPTOCOCCACEAE*
ROlHL-20963-01 Experimental lung abscess (rabbits)
MICROORGANISMS, ANAEROBES
P50HL-19362-02 0009 A/S SCOR -Atherosclerosis in
nonhuman primates ■ Cholesterol metabolism and
intestinal microflora (baboon)
R01HL-2096301 Experimental lung abscess (rabbits)
MICROORGANISMS VIRULENCE
SEE ALSO BACTERIAL DISEASES, CYTOPATHOGENIC EFFECT
BACTERIAL
SEE ALSO DRUGS RESISTANCE. MICROBIAL
SEE ALSO VIRUS DISEASE CHARACTERISTICS.
CYTOPATHOGENIC EFFECT VIRAL
ROlHL-19381-03 Pathogenesis of viral induced
atherosclerosis (human, chicken)
MICROPHONE, PROBE TUBE
SEE RESPIRATORY DISORDERS DIAGNOSIS, RESPIRATORY
AIRFLOW MEASUREMENTS*
MICROPUNCTURE
SEE DIAGNOSTIC TESTS, BIOPSY. MICROPUNCTURE*
MICRORADIOGRAPHY
SEE RADIOGRAPHY. MICRORADIOGRAPHY*
MICROSCOPY (GENERAL)
SEE OPTICS. MICROSCOPY (GENERAL)*
MICROSOMES
SEE CELL COMPONENTS. MICROSOMES
MICROTUBULES
SEE CELL COMPONENTS. MICROTUBULES (GENERAL)
MICROWAVE HEATING
SEE TEMPERATURE, HEAT, MICROWAVE HEATING
MICROWAVE RADIATION
SEE RADIATION, ELECTROMAGNETIC WAVES. MICROWAVE
RADIATION
MICROWAVE THERMOGRAPHY
SEE TEMPERATURE MEASUREMENT, THERMOGRAPHY*
MIDBRAIN
SEE BRAIN, MESENCEPHALON
MIDCHILDHOOD
SEE CHILDREN, MIDCHILDHOOD (6 TO 12 YRS)
MIDDLE AGE
SEE AGE (HUMAN), ADULT, MIDDLE AGE (45 TO 64 YRS)
MIDDLE EAR DISORDERS
SEE EAR DISORDERS. MIDDLE EAR DISORDERS
MIF (LYMPHOKINES)
SEE HYPERSENSITIVITY. LYMPHOKINES. MIGRATION
INHIBITORY FACTOR
MIGRANTS
SEE SOCIOENVIRONMENT, RESIDENTIAL MOBILITY. MIGRANTS
(contd)
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
•*Onented significantly to above subject.
M Grant has subproiects describing specific research aspects.
See Appendix for investigator's name and grant number.
MIGRANTS (SOCIOLOGY)
SEE SOCIOfNVIRONMENI. RESIOeNTlAl MOBILITY, MIGRANTS
MIGRATION, CELL
SEE CELL MIGRATION
MIGRATION INHIBITORY FACTOR
SEE HYPERStNSIIIVIIY. LYMPHOKINES. MIGRATION
INHIBITORY fACIOR
MILK
SEE BODY FLUIDS. MILK
MIUIPORE-DOHP MEMBRANE
SEE BIOLOGICAL TRANSPORT. MEMBRANE MODELS
MIND CONTROL
SEE PSYCHOLOGY. BRAIN CONTROL
MINERAL BALANCE ■ METABOLISM
SEE CALCIUM (MINERAL) BAUNCE (METABOLISM)
MINERALIZATION INHIBITORS
SEE CALCIFICATION INHIBITORS (CALCIUM NEGATIVE
BALANCE DRUGS)
MINERALOCORTICOIDS
SEE ADRENAL CORTEX HORMONES. MINERALOCORTICOIDS
MINERALS
SEE CHEMICALS (GENERAL). MINERALS (GENERAL)
MINERALS IN THE DIET
SEE NUTRITION, DIETARY CONSTITUENTS, DIETARY TRACE
ELEMENTS AND MINERALS
MINIATURE SWINE
SEE MAMMALS. ARTIODACTYLA. SWINE, MINIATURE SWINE*
MINING
SEE OCCUPATIONS, INDUSTRY, MINING
MINORITY GROUPS
SEE SOCIAL GROUPS. MINORITY GROUPS
MINOXIDIL
SEE PYRIMIDINES, MINOXIDIL
MIST TENT THERAPY, RESPIRATORY DISORDERS
SEE RESPIRATORY ASSIST AND OXYGEN ADMINISTRATION,
AEROSOL THERAPY
MITOCHONDRIA
SEE CELL COMPONENTS. MITOCHONDRIA
MITOCHONDRIAL DNA (INHERITANCE)
SEE NUCLEIC ACIDS, MT DNA
MITOCHONDRIAL MEMBRANE
SEE CELL COMPONENTS. MITOCHONDRIAL MEMBRANE
MITOGENIC FACTORS, PLANT
SEE PLANTS PROTEINS. LECTINS
MITOGENS
SEE ALSO PLANTS PROTEINS. LECTINS
POlHL-06314-17 0050 Immunologic mechanisms in
cardiovascular disease - Physiologic changes in
lymphocytes (human, mice)
POlHL-06314-17 0053 Immunologic mechanisms in
cardiovascular disease - Cellular functions controlled by
cyclic GMP (human, mice, guinea pigs)
** POlHL-06314-1? 0067 Immunologic mechanisms in
cardiovascular disease - Mitogenic and antigenic activation
of lymphocyte sub-populations
ROlHL-19819-03 Mitogen induced interstitial pneumonitis
(rabbits)
R23HL-21134-02 Immune function and fibrogenesis in
silicosis (guinea pigs)
MITOMYCIN
SEE ANTIBIOTICS. MITOMYCIN C
MITOSIS
SEE CELL DIVISION. MITOSIS
MITRAL INSUFFICIENCY
SEE HEART DISORDERS. VALVULAR INSUFFICIENCY, MITRAL
INSUFFICIENCY
MITRAL STENOSIS
SEE HEART DISORDERS. VALVULAR. MITRAL STENOSIS
MITRAL VALVE
SEE HEART, VALVES, MITRAL VALVE
MIXED CELL CULTURES
SEE TISSUE (CELL) CULTURE, MIXED CULTURES
MIXED FUNCTION OXIDASES
SEE OXYGENASES. MIXED FUNCTION (GENERAL)
MIXED LEUKOCYTE CULTURE (TEST)
SEE TISSUE COMPATIBILITY-TRANSPLANT.
HISTOCOMPATIBILITY TYPING. MLC
MIYAGAWANELLA
SEE CHLAMYDIA
MK 185
SEE PHENOXYACETIC ACIDS, HALOFENATE
MLC TEST (MIXED LEUKOCYTE CULTURE)
SEE TISSUi COMPAIIBIlllYIRANSPIANI,
HISTOCOMPATIBIIIIY TYPING, MIC
MLV (MOUSE LEUKEMIA VIRUSES)
SEE VIRUSES, ONCORNA. LEUKEMIA MOUSE
MNSS SYSTEM
SEE BLOOD GROUPS, MNSS SYSTEM
MOBILITY. RESIDENTIAL
SEE SOCIOENVIRONMENT. RESIDENTIAL MOBILITY
MODEL CHANNEL
SEE BIOLOGICAl TRANSPORT, MEMBRANE MODELS
MODELS (GENERAL)
SEE ALSO COMPUTER SIMULATION
SEE ALSO ENZYME MODELS
POlHL-06314 17 0052 Immunologic mechanisms in
cardiovascular disease Role of cyclic nucleotides in
neutrophil function (human)
ROlHL-11717 09 Effect of stenotic obstructions on flow in
arteries (dogs)
ROlHL-12677 10 Surgical physiologic studies of isolated
kidneys (dogs, rats)
M POlHL-15194 07 Pathophysiology of cardiopulmonary
dysfunction
ROIHL 17407-05 Peripheral circulation and fluid balance
(fish, mammals, human)
ROIHL 17821 03 Cavitation phenomena near prosthetic
devices
POlHL-18576-03 0010 Thrombosis research program
project - Evaluation of non-thrombogenic materials (cattle)
ROlHL-18647-03 Ischemic myocardial injury in cultured
heart cells (rats)
ROlHL-191 18-03 Measurement of airways mechanics
(human, dog)
ROlHL-20607-02 Tissue analysis by mass spectrometer
(dogs)
ROIHL 20829-02 Fluid mechanics of heart valve
prostheses (dogs, human)
POlHL-20948-02 0002 Molecular basis of cholesterol
metabolism - LDL pathway in cell lines with informative
properties other than fibroblasts
POIHL 20948 02 0003 Molecular basis of cholesterol
metabolism - LDL pathway in vivo (human, rats, guinea
pigs)
ROlHL-21429-02 Transport of LDL in arterial wall (human,
mammals)
ROlHL-2233801 Platelet adhesion and aggregation in a
flow chamber (human)
R01HL-22583-02 Ultrastructural study of endothelium in
thrombosis (human)
** N01HV-62957-05 Coordinating center model for NHLI
clinical trials
MODELS, BIOLOGICAL
SEE ALSO BIOLOGICAL TRANSPORT. MEMBRANE MODELS
ROlHL-01015-27 Hypertension and left ventricular
hypertrophy (dogs)
ROlHL-01803-23 0001 Arteriosclerosis, glomerulonephritis.
rheumatic fever - Poststreptococcal glomerulonephritis
(rabbit)
ROlHL-01803-23 0005 Arteriosclerosis, glomerulonephritis.
rheumatic fever - Immunologic and dietary synergy in the
pathogenesis of atherosclerosis (rabbits)
ROlHL-01803-23 0010 Arteriosclerosis, glomerulonephritis.
rheumatic fever - Atherosclerosis induction-Graft rejection
and hypercholesterolemia (rabbits)
ROlHL-01803-23 0011 Arteriosclerosis, glomerulonephritis.
rheumatic fever ■ Immunopathologic consequences of
cigarette smoking (human, rabbits, plants)
ROlHL-01803-23 0015 Arteriosclerosis, glomerulonephritis.
rheumatic fever - Immunologic endothelial injury and lipid
diet atherosclerosis (rabbits, monkey)
ROlHL-01803-23 0019 Arteriosclerosis, glomerulonephritis.
rheumatic fever - Pathogenesis of rheumatic heart disease
(rabbit)
ROlHL-02363-20 Kinetics of water and electrolytes in
shock (dogs, rats)
ROlHL-02942-22 Biochemistry of cardiovascular connective
tissue (human, cattle, primates)
ROlHL-03180-21 Relation of lymphatics to
cardiopulmonary function (dogs)
R01HL03181-21 0028 Hemodynamics as applied to
surgical problems - Extrarenal factors in the hypertension
of coarctation (dog)
R01HL-a5209-18 Lipid metabolism (monkeys)
ROlHL-05806-18 Analysis of antiarrhythmic agents (dogs.
rabbits)
P01HL06285-18 0153 Cardiovascular-respiratory
physiology and biochemistry - Myocardial mechanics and
pharmacology in isolated papillary muscle (animals)
POlHL-06285-18 0200 Cardiovascular-respiratory
physiology and biochemistry Medullary counter-current
system (animals)
POlHL-06285-18 0204 Cardiovascular-respiratory
physiology and biochemistry - Lipoprotein lipase and
triglyceride transport in chylomicrons (guinea pig, rat)
POlHL-06296-18 0007 Cardiovascular and pulmonary
adaptation to stress - Cardiovascular control during
isometric exercise (cats)
POIHI 06308 18 0038 Me(.hanllm^ and therapy ol
circulatory disease Eleclrophysiolo(y of vcniricuair
arrhythmias associated with ischemia (dogs)
POIHL 0631? 1/ 0016 Surgical cardiology Effect of
hydralazine on infarct si/e following coronary occlusion
(human)
Immunologic mechanisms in
Role ol intravascular coagulation
POIHL 06314 17 004/
cardiovascular disease
(human, animals)
POIHI 06314 1/ 0060
cardiovascular disease
Immunologic mechanisms in
Strept antigens and infections in
cardiovascular complications {human, animals)
POlHL-06314 17 0061 Immunologic mechanisms in
cardiovascular disease Role ol viruses in cardiovascular
and renal disease (human, mice)
POIHL 06370 17 0001 Cardiopulmonary and renal
pathology research center The humoral and cellular
mechanisms of allograft reiection (monkeys)
POIHL 06370 17 0014 Cardiopulmonary and renal
pathology research center Quantitative morphology in
cardiac disease (human, rats, dogs)
P01HL06664-17 0036 Cardiopulmonary function in
remediable vascular disease In vitro studies on the
mechanism of ischemic damage to cells (rabbits)
P01HL06835 17 0016 Cardiovascular disease Metabolic
interactions to polyunsaturated fatty acids in atherogenic
diet (dogs)
P01HL06835 17 0037 Cardiovascular disease Cardiac
hypertrophy in spontaneously hypertensive rat
POlHL-06835-17 0040 Cardiovascular disease Benign
and malignant phase of renal hypertension (dogs)
POlHL-06835-17 0059 Cardiovascular disease
Metyrapone-induced hypertension in dog
R01HL07776-15 Sudden death and cardiac arrhythmias
(human, dogs, cats)
ROlHL-07835-17 Experimental hypertension and renal
circulation (rats, rabbits)
POlHL-07896-15 0008 Environmental biomedical research
program ■ Otologic studies under hyperbaric conditions
(human, animals)
POlHL-07896-15 0009 Environmental biomedical research
program Decompression sickness and computation of safe
diving tables (human, animals)
POlHL-07896-15 0036 Environmental biomedical research
program - Respiratory heat loss in deep diving (infants,
dogs)
P01HL07896-15 0050 Environmental biomedical research
program - Fundamental decompression concepts using the
rat animal model
POlHL-0868215 0021 Regulation of the cardiovascular
system - Hypoglycemia in pathogenesis of shock (dog)
POlHL-08974-14 0024 Natural and experimental
atherosclerosis - Atherosclerosis, sterol and lipoprotein
metabolism in nonhuman primates
ROlHL-09234-13 Amino acids of contractile proteins of
failing hearts (dogs, hamsters)
ROlHL-0974414 Experimental vascular sclerosis
(monkeys, rabbits)
ROlHL-09902-13 Comparative study of coagulation and
vascular disease (animals)
P01HL10342-13 0028 The integrated function of
respiration and circulation - Mediator release.
hemodynamics and respiratory function in anaphylaxis
(dogs)
R01HL-I058212 Thrombosis and hemostasis-Analysis.
methods and standards (human, cattle, venom)
R01HL10914-10 Renal sodium transport in experimental
aldosteronism (dogs)
POlHL-11310-12 0063 Mechanisms of cardiovascular
disease - Myocardial function, metabolism and cellular
integrity after heart surgery (dogs)
POlHL-11310-12 0078 Mechanisms of cardiovascular
disease - Ventricular arrhythmias in acute myocardial
infarction (dogs)
POlHL-1 1414-11 0034 Thrombosis and atherosclerosis
program - Servo simulation-Experimental myocardial
infarction (dogs)
POlHL-1167811 Cardiovascular dynamics and their
control
POlHL-11678-11 0069 Cardiovascular dynamics and their
control - Nervous control of the cirulation (dogs)
R01HL11717-09 Effect of stenotic obstructions on flow in
arteries (dogs)
ROlHL-1 1876-11 Regional myocardial blood flow and
metabolism (dogs, swine)
ROlHL-1 1901-12 0020 Effects of metabolic surgery on
the hyperlipidemias - jejunoileal bypass-Endogenous
animal model of obesity (rats)
ROlHL-12307-08 Non-surgical treatment of congenital
heart disease (human, dogs)
ROlHL-12399-13 Specific fatty acids and cholesterol
metabolism (gerbils. rats)
ROlHL-1261409 Microcirculatory control mechanisms and
hypertension (bats, rats)
ROlHL-12650-08 Environmental pathobiology of the lung
(hamsters, rats)
POlHL-12738-10 0044 Physiologic pharmacology and its
clinical applications - Cardioactive drugs and
electrophysiological properties of cardiac cells (sheep)
POlHL-1273810 0076 Physiologic pharmacology and its
clinical applications
MI6
POlHL-12738-10 0081 Physiologic pharmacology and its
clinical applications - Ultrastructural and electrophysiologic
alteration of myocardium (human, dogs)
POlHL-12738-10 0098 Physiologic pharmacology and its
clinical applications - Skeletal muscle support of the
chronically failing heart (dogs)
POlHL-12738-10 0110 Physiologic pharmacology and its
clinical applications - Physiology and pharmacology of
arrhythmias (dogs)
P01HL1273810 0123 Physiologic pharmacology and its
clinical applications - Ventricular assistance and
preservation (human, dogs)
POlHL-12738-10 0132 Physiologic pharmacology and its
clinical applications - Coronary occlusions and arrhythmias
(dogs)
R01HL'127ee'09 Structure-function relation of blood
vessels (rats, monkeys)
ROIHL'1299707 Myocardial defects induced by potassium
depletion (human, rats, cats)
R01HL13036-08 Coronary thrombosis -Effects on
myocardium and in vivo detection (dogs, monkeys)
ROlHL-13193-09 Pathophysiology of post-traumatic and
shock states (rodents, dogs)
ROlHL-1325709 Inhalation anesthesia on myocardial
metabolism (dogs, swine, human)
POIHL 13330-08 0059 Mechanical circulatory support -
Physiologic evaluation of circulatory assistance (cattle)
ROlHL-13454-08 Behavioral stress and cardiomyopathy
(monkeys, cats)
ROlHL-13466-08 Pulmonary platelets in shock, trauma
and embolization (dogs, pigs, rats)
POIHL- 13480-09 0026 Cardiac electrophysiology - Neural
influences on cardiac electrophysiology and contraction
(dog, cat)
POlHL-13480-09 0028 Cardiac electrophysiology - Stress
electrocardiography (human, dogs)
ROlHL-13639-07 Factors altering the course of myocardial
dysfunction (cats)
' ROlHL-13645-11 Tryptophan-induced pulmonary
emphysema (cattle, goats, rabbits)
ROIHL 13929-06 Single nephron response to chronic
obstruction (frogs, rats)
R01tlL13936-06 Microvascular responses in hypertension
(human, rats)
P50HL-14136-07 0001 Pulmonary SCOR-Airways
obstructive diseases - Experimental airway obstructive
disease (dogs)
P50HL-14138-05 0015 Center for research on
atherosclerosis - Arterial wall-Intermediary metabolism.
enzyme activity and bioenergetics
P50HL-14141-05 0003 SCOR for atherosclerosis in
childhood - Detection of abnormalities in lipid metabolism
(human, rabbits, rats)
P50HL-14159-08 0024 Specialized center of research in
hypertension - Core resources (clinical, animal models)
P50HL-14164-07 A/S SCOR -Comparative and experimental
atherosclerosis
' P50HL14164-07 0027 A/S SCOR-Comparative and
experimental atherosclerosis - Hyper- and
hyporesponsiveness to dietary cholesterol (squirrel monkey)
* P50HL-14164-07 0028 A/S SCOR-Comparative and
experimental atherosclerosis - Hyper- and
hyporesponsiveness to dietary cholesterol (African green
monkey)
* P50HL-14164-07 0029 A/S SCOR-Comparative and
experimental atherosclerosis - Development of pigeon
substrains
* P50HL-14164-07 0030 A/S SCOR-Comparative and
experimental atherosclerosis ■ Morphology, angiochemistry-
Diet induced lesions in African green monkey
* P50HL-14164-07 0031 A/S SCOR-Comparative and
experimental atherosclerosis - Changes in endothelial
permeability associated with atherosclerosis (pigeon)
P50HL-14164-07 0032 A/S SCOR-Comparative and
experimental atherosclerosis - Plasma cholesterol, lesion
regression and vascular function (Rhesus monkey)
P50HL-14212-07 0006 Correlated studies of pulmonary
fibrosis - Alveolar macrophage physiology (human, rodents,
rabbits)
P50HL-14212-07 0014 Correlated studies of pulmonary
fibrosis - Pulmonary lavage cells, secretions in diffuse
intersititial lung disease (human)
* P50HL-14214-07 0035 Newborn lung center for hyaline
membrane disease - Core-Animal care facility
ROlHL-14271-07 Physico-chemical properties of tracheal
mucus (dogs, frogs)
* POlHL-14388-07 0195 Regulation of the circulation in
pathological states - General review of potential
pathophysiologic factors in spontaneous hypertension
POlHL-14388-07 0196 Regulation of the circulation in
pathological states - Altered vascular responsiveness In
spontaneous hypertension (rats)
POlHL-14388-07 0218 Regulation of the circulation in
pathological states - Regional myocardial dyskinesis-Cause
assessment and reduction (dogs)
POlHL-14414-07 0004 Environmental influences on
cardiorespiratory and cellular functions - Role of diffusion
in gas exchange (chicken egg)
P01H1.-14414-07 9002 Environmental influences on
cardiorespiratory and cellular functions - Core-Computer
facility
346
ROlHL-14526-07 Oral contraceptives and hypertension
(rats)
ROlHL-14545-06 Mechanics of compensatory ventricular
hypertrophy (dogs)
ROlHL-147 17-06 Hemodynamics and heart structure-
Ventricular overload (dogs)
ROlHL-14799-07 Cardiac heterotransplantation-
Immunologic modification (mice, rat)
ROlHL-14854-07 Lung and tissue mechanics (monkeys,
dogs)
R01HL14913-06 Hypertension -Genetic influence of kidney
(rats)
POlHL-14985-07 0003 Adaptation to hypoxia - Hypoxia
and oxygen transport (human, dogs)
POlHL-14985-07 0005 Adaptation to hypoxia - Control
mechanisms in the pulmonary microcirculation (animals)
POlHL-14985-07 0007 Adaptation to hypoxia - Control of
pulmonary circulation, histamine and the sympathetics
(animals)
POlHL-14985-07 0010 Adaptation to hypoxia - Pulmonary
mast cell (animals)
POlHL-14985-07 0011 Adaptation to hypoxia -
Prostaglandins in the control of the pulmonary circulation
(animals)
P50HL-15061-07 0010 Response of lung to injury - An
animal model system for the study of bronchiolitis and its
sequellae (dogs)
P50HL-15062-07 0020 Study of lipoproteins, artery wall,
and atherosclerosis - Artery wall reactions -Elevated
pressure and hypertipemia (monkey)
P50HL-15092-07 0008 Immune and fibrotic response to
occupational environments - Animal models of asbestosis
(hamsters)
P50HL-15103-07 0013 A/S SCOR-Early natural history of
arteriosclerosis - Experimental models of atherosclerosis
(monkeys)
ROlHL-15124-05 Genesis of hypertension in renal disease
(human, dogs)
' P60HL-15160-07 0011 Center for sickle cell disease -
Study of human sickle cells in an animal model (rats)
P60HL-15162-07 0019 Comprehensive sickle cell center -
RBC-Blood rheology in sickle cell anemia and related
disorders (human, animal)
ROlHL-15247-05 Extending the life of implanted
pacemakers (dogs, human)
ROlHL-152 70-06 Local mechanical properties of the aortic
tissue (dogs, pigs)
ROlHL-15307-06 Central nervous control of renin and
blood pressure (dogs)
• P50HL-1538907 0011 Pulmonary SCOR -Hypersensitivity
pneumonitis - Animal model-Hypersensitivity pneumonitis
in rabbits
' P50HL-15389-07 0012 Pulmonary SCOR-Hypersensitivity
pneumonitis - Animal model-lmmunologic lung disease in
guinea pigs
ROlHL-15444-Oe Neonatal development of adrenergic
receptor mechanisms (pigs)
ROlHL-15504-05 Animal model for studies on averting
atherosclerosis (swine)
' ROlHL-1551206 Drug treatment of stenosing primate
atherosclerosis (rabbits, monkeys)
ROlHL-15520-06 Total blood replacement by fluorocarbons
and polyols (rats)
ROlHL-15522-06 Influence of mannitol on ischemia
cardiac muscle (dogs, cats, rats)
R01HL15528-05 Renin kinetics in hypertensive and
uremic plasma (human, dogs)
R01HL15580-06 Humoral control of pulmonary and
systemic circulation (animals)
ROlHL-15593-05 Prokinged extracorporeal cardiopulmonary
support (rats, sheep, rabbits)
ROlHL-15607-06 Physiological control of splanchnic
circulation (dogs)
ROlHL-15681-06 Coronary flow studies of partially
obstructed vessels (dogs)
ROlHL-15797-05 Lipid metabolism and atherosclerosis in
primates (monkeys, human, squirrels)
ROlHL-15852-06 Vascular ion transport and hypertensive
mechanisms
P60HL-15999-05 0019 Miami comprehensive sickle cell
center - Fetal-adult hemoglobin switch (mouse, monkey)
P60HL-1600806 0014 Wayne State University
comprehensive sickle cell center - Zinc and red blood cell
metabolism in sickle cell anemia (rats, human)
R01HL16029-05 Bio-organic chemistry of ozone, nitrogen
dioxide and tobacco smoke
POlHL-161 18-06 0005 Study of emphysema -
Mechanisms of elastase emphysema (mice)
POlHL-161 18-06 0006 Study of emphysema - Metabolism
of elastin (hamsters)
ROlHL-161 19-05 Spleen and marrow allografts in
hereditary anemia (mice)
ROlHL-16154-05 Membrane lung perfusion for acute
respiratory failure (sheep, baboons)
ROlHL-162 19-05 Mechanisms of atherogenesis in chronic
uremia (human, rats)
ROlHL-16233-05 Molecular cardiology of MDP-induced left
ventricular failure (dogs)
ROlHL-16292-05 0018 Surgery and non-obstructive
coronary insufficiency - Unavoidable subendocardial
perfusion caused by venting and hypothermia (dogs)
MOD
ROlHL-16292-05 0019 Surgery and non-obstructive
coronary insufficiency - Distortion of subendocardial vessels
in Infant hearts (dogs)
ROlHL-16292-05 0020 Surgery and non-obstructive
coronary insufficiency - Limitation of transthoracic ECG in
detecting subendocardial ischemia (dogs)
POlHL-16387-04 0003 The blood vessel and
thrombogenesis - Blood vessel healing (rabbits)
R0IHL-ie454-03 Vascular muscle reactivity in
hypertension (human, rats)
ROlHL'16490'04 Structural basis of nephron filtration
(rats, rabbits)
R01HL-16S87-04 Cholesterol binding saponins and
atherosclerosis (monkeys)
ROlHL-16656-06 Left ventricular function in exercise
(dogs)
ROlHL-16706-04 Excitation-contraction coupling and heart
failure (dogs, rabbits)
POlHL-16769-05 0003 Pathobiologic and host defense
reactions in the lung - Pathobiologic mechanisms of
delayed sensitivity reactions in the lung (animals)
P01HL-ie878-05 0001 Control of ventilation in health
and disease - Ability of asthmatics to detect added
resistive and elastic loads
ROlHL-16916-04 0002 The role of albumins in lung water
accumulation - Lung water balance-Forces, models and
albumin concentrations (rabbits, dogs)
ROlHL-16952-05 Cardiovascular pathology (rats, rabbits)
R01HL17091-05 Anesthetics and microvascular response
to hemorrhage (rats)
ROlHL-17243-05 Cause of chronic experimental renal
hypertension (dogs, rabbits)
P60HL-17269-04 0007 National heart and blood vessel
research and demonstration center - Correlative studies of
experimental myocardial ischemia (dog)
' P60HL-17269-04 0024 National heart and blood vessel
research and demonstration center - Section of
experimental cardiovascular surgery-Core facility
P60HL-17269-04 0033 National heart and blood vessel
research and demonstration center - Autoallergic response
in cardiomyopathy, atherosclerosis, rheumatic heart disease
ROlHL-17335-05 Contractile properties of hypertensive
arterioles (rats)
' ROlHL-17352-03 Physiological regulation during chronic
hyperthermia (sheep)
ROlHL-17358-04 Ventilatory adjustments for optimal
oxygenation (dogs, rats)
ROlHL-17366-05 Mechanisms in the production of renal
hypertension (rabbits, dogs)
ROlHL-17369-04 Arterial bypass surgery-Structure and
metabolism (monkeys)
ROlHL-17370-03 Synaptic chemistiy and cardioregulation
in Limulus
ROlHL-17404-05 Immunologic mechanisms in heart
disease (mice)
POlHL-17419-04 0001 Studies on mechanisms of
hemostasis - Structure and metabolism of fibrinogen
(human)
POlHL-17421-05 0001 Regulation and exchange in the
microcirculation - Mass transfer and microcirculatory
function (rats)
POIHL- 17430-05 0001 Control of coagulation - Porcine
von Willebrand's disease
ROlHL-17458-04 Renal control of sodium excretion (rats)
ROIHL- 174 79-04 Blood storage-The production of
cardiotoxic material (dogs, human, swine)
ROlHL-17516-04 Role of androgen as a risk factor in
atherogenesis (human, animals)
ROlHL-17564-03 Unsaturated fats-Mode of
hypocholesterolemic action (minipig)
ROlHL-17581-03 Patent ductus arteriosus and pulmonary
hypertension (dogs)
ROlHL-17631-05 Experimental congestive heart failure and
hypertrophy (cats)
* P50HL-17646-04 0004 Study of ischemic heart disease -
Core experimental animal laboratories
* P50HL1 7648-04 0021 Study of ischemic heart disease ■
Biventricular contractile responses to acute myocardial
infarction (mammals)
P50HL-17651-04 0016 Ischemic heart disease specialized
center of research Retroperfusion of coronary venus
circulation with therapeutic agents (dogs)
* P50HL-17682-04 0018 Study of ischemic heart disease -
Biochemistry of ischemia -Heart cell and organ culture
(mice. rats, cattle)
ROlHL-17705-04 Kallikrein-kinin system in hypertension
(human, rats, dogs)
ROlHL-17706-04 Psychosocial hypertension,
catecholamines and drugs (mice)
ROlHL-17781-03 Hypertension, kidney disease and renal
lymph (dogs, rats)
ROlHL-17809-04 Effects of exercise on the coronary
vasculature (rat, dog)
ROlHL-17847-04 Cardiovascular and renal functions of
marmots
ROlHL-17853-03 Peripheral circulation in heart failure
(animals)
POlHL-17871-04 0009 Kidney, sodium, cardiac output.
arterioles and hypertension - Kidney, sodium, cardiac
output, arterioles and hypertension
(contd)
'Excludes routine methodok)gy OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subproiects describing specific research aspects
See Appendix for investigator's name and grant number
IIG
POIHL 1787104 0010 Kidney, sodium, cardiac output.
■ritnolts and hypeitanslon Renal prostaglandins
metabolism in liypertension (tats, dogs)
POIHL W87I 04 0013 Kidney, sodium, cardiac output.
arterioles and hypertension Pertusion pcessuce and lenal
sodium excretion (rats)
347
Eiiperimental neurogenic
Model ol sustained arterial
ROIHI 17902 04
(hamsters)
ROIHL 1790704
(pigs. cats, rats)
ROIHI 17944 03
ROIHL 1797004
Mammalian renal microcirculation
Brain regulation ol cardiac arrhythmia
Studies in lung preservation (dogs)
Vascular effects of inhibitory behavioral
adaptations (dogs)
ROIHL 18024 03 Regional myocardial flow and function
relationships (dogs)
ROIHL 18027 03 New vasoactive factors and their role in
hypertension (human, dogs, rats)
ROIHL'18060'04 Exercise and coronary atherosclerotic
heart disease (monkeys)
R01HL1809704 Pathogenesis of acute renal failure (rats)
ROIHL 1814804 Adrenal catecholamine secretion
ROlHL-1818604 Cardiac allografts in autologous
radiation chimeras (rats, dogs)
ROIHL 1819104 Models of hypoxic pulmonary
hypertension (cattle, mmipigs)
R01HL1830803 Comprehensive studies of mucociliary
transport (dogs)
P50HL1831803 0002 Pathogenesis and complications of
hypertension Core experimental animal facility (rats,
rabbits)
P50HL 1831803 0007 Pathogenesis and complications of
hypertension ■ Humoral factors and renal function in
experimental hypertension (rats)
P50HL- 183 1803 0014 Pathogenesis and complications of
hypertension - Arterial metabolism and atherogenesis (rat,
rabbit)
ROlHL-1834004 Electron microscopy of the
juxtaglomerular apparatus (rats)
ROlHL-18398-04 Mechanisms of delayed and asymetric
ventricular conduction (human, dogs)
ROlHL-18468-03 The distribution of flow in the
myocardium (dog. pig)
R01HL18492-03 Measurement of regional coronary flow
reserve (human, dogs)
R01HL18527-03 Subcellular response of heart to
functional overload (hamsters, rats)
R01HL18537O4 Regional blood flow after acute
myocardial injury (dogs)
P01HL18574-03 0004 Lipoprotein methodology and
biomedical applications - Fine structure and metabolism of
lipoproteins-EM studies (guinea pigs)
POlHL-18575-03 Mechanisms of vascular changes In
hypertension
POlHL-18575-03 0001 Mechanisms of vascular changes
in hypertension ■ Arteries and resistance vessels in
hypertension (pigs, rats)
P01HL18575-03 0010 Mechanisms of vascular changes
in hypertension - Hypertensive pig Core
POlHL-18576-03 0007 Thrombosis research program
project ■ Relationships between coagulability and
thrombosis (human, animals)
POIHL-18576-03 0009 Thrombosis research program
project - Biology of factor VII (human, rabbits, cattle)
R01HL1857903 Vasoactive hormones and blood pressure
regulation (dogs, rats, rabbits)
ROlHL-18607-03 Metabolic and drug studies on
experimental fat embolism (mice)
ROlHL-18629-04 Influence of aging and hypertension on
the myocardium (rats)
P01HL-18645-03 Biology of the artery wall and
atherosclerosis
P01HL18645-03 0001 Biology of the artery wall and
atherosclerosis • Primate arterial smooth muscle and
atherosclerosis
■ P01HL18645-03 0006 Biology of the artery wall and
atherosclerosis ■ The platelet and atherosclerosis (monkeys,
baboons)
P01HL18545-03 0007 Biology of the artery wall and
atherosclerosis - Lipoprotein metabolism in subhuman
primates
POIHL- 18646-03 0008 Studies basic to heart
transplantation - Immunophysiology and early detection of
rejection (dogs)
POlHL-18708-03 0010 Oxygen, energy and contractility in
cardiac tissue - Tissue oxygen utilization (rats, dogs)
R01HL18749-03 Ventricular mechanics in the overloaded
heart (dogs)
ROIHL 1879804 0003 Nervous and ionic factors in
sudden cardiac death - Lett stellectomy in the prevention
of sudden death (dogs)
* ROlHL-1883103 Microscopy of spontaneously hypertensive
arterial lesion (rats)
ROlHL-1884803 Etiology and development of congenital
heart disease (dogs, cats)
ROlHL-18875-03 Angiotension, prostaglandins, pressure
and the kidney (rats)
ROIHL-1893602 Heart preservation and transplantation
studies (rat)
ROlHL-1893803 Pulmonary fatty acid and phospholipid
metabolism (rats)
ROlHL-18952-03 Metabolism in perfused fetal and
newborn rabbit lungs
POIHL 1897403 0006
hypertension program
hypertension (cats)
ROIHL 18977 03 Non invasive diagnosis of peripheral
arterial disease (human, dogs)
ROIHL 18997 02 Ischemic therapy in experimental
hypersplenism (rats, dogs)
ROIHL 19012 03 Smooth muscle of resistance vessels in
hypertension (rats)
ROIHL 19045 03 Electrophysiology of cardiac automaticity
(human, dogs)
ROIHL 19062 03 Pharmacologic control ol mast cell
phosphodiesterase (human, rats)
ROIHL 19072 03 Modification of tissue injury in
myocardial infarction (dogs, human)
ROIHL 19091 02 Sustained increase in cardiac output
(dogs)
ROIHL 1910903 Regression of chronic atherosclerosis
(rabbits)
P50HL 1915302 0007 SCOR Pulmonary edemas- Eitology,
pathogenesis Core Experimental laboratories and support
facilities
P50HL 1915702 0004 Studies in cystic fibrosis and
bronchiolitis Macromolecular regulators of mucus
secretion -Invertebrate model
P50HL 19160-02 0001 Mucus abnormality in cystic
fibrosis Regulation of respiratory secretions (rat, human)
P50HL-19160-02 0002 Mucus abnormality in cystic
fibrosis Ultrastructure, cytochemistry of pulmonary
secretion (human, rat)
' P50HL-19171-02 0006 Pulmonary SCOR -Lung injury by
childhood infections Development of model systems
(bacteria, viruses, hamsters)
P50HL-19187-02 0013 Pediatric pulmonary SCOR-Hyaline
membrane disease Research resources core
ROIHL 19203-03 Surgical approach to congenital heart
diseases (dogs, primates)
ROlHL-1920403 Environmental factors in hypertension
(Rhesus monkeys)
R01HL19225-02 Types and mechanims of pulmonary
hypertension
Types and mechanims of
- Structural changes (human.
ROlHL-19225-02 0001
pulmonary hypertension
animals)
ROlHL-19225-02 0002
pulmonary hypertension
(pigs)
ROlHL-1922502 0003
pulmonary hypertension
and rats
R01HL19225-02 0004
pulmonary hypertension
Types and mechanims of
- Effect of aorto-pulmonary shunt
Types and mechanims of
- Cardiopulmonary function in pigs
Types and mechanims of
Structural changes in human
pulmonary circulation (human, animals)
R01HL19251-03 An index of sympathetic activity in
hypertension (rats)
POlHL-19259-03 0004 Digoxin-specific antibody in human
therapy - Digitalis-specific antibodies pharmacological
studies (human, dogs, sheep)
ROlHL-19287-03 The antihypertensive function of the
renal medulla (human, rats, rabbits)
P50HL-1936202 A/S SCOR -Atherosclerosis in nonhuman
primates
P50HL-19362-02 0004 A/S SCOR -Atherosclerosis in
nonhuman primates - Selective breeding for characters
related to atherosclerosis (baboons)
P50HL-19362-02 0005 A/S SCOR -Atherosclerosis in
nonhuman primates - Hybridization to produce primate
model of atherosclerosis (baboon. Rhesus)
P50HL-19362-02 0006 A/S SCOR -Atherosclerosis in
nonhuman primates - Effects of cigarette smoking on
atherosclerosis (baboon)
P50HL-19362-02 0016 A/S SCOR-Atherosclerosis in
nonhuman primates - Core laboratory-Animal services
(baboon)
R01HL19374-03 Pharmacology of kinins in cardiovascular
disease (rats, rabbits)
ROlHL-19398-03 Regional conduction abnormalities and
arrhythmias (dogs)
ROlHL-19425-03 Cardiac function in hypertrophy (dog)
ROlHL-19461-03 Myocardial energetics in hypertrophy and
heart failure (rabbits)
ROlHL-19467-03 Regulation of blood pressure (rats, dogs)
ROlHL-19486-03 Dipole moment measurement of cardiac
mass (rabbits, pigs)
ROlHL-19538-03 Synthesis of potential antihypertensive
agents
ROlHL-19539-03 Pathology of hypertensive-associated
arteritis (rabbits)
R01HL-19628-03 Mechanisms of pulmonary alveolar
proteinoses (human, rats)
R01HL-19648-03 Myocardial protein degradation (dogs,
rabbits)
ROlHL-19673-03 Surgical aspects of shock and hypoxia
(dogs, monkeys, rats)
POlHL-197 17-02 Response of the lung to injury
POlHL-19717-02 0003 Response of the lung to injury -
The role of elastolysis in emphysema (hamsters, rabbits)
POlHL-197 17-02 0005 Response of the lung to injury -
Studies on proteolysis and lung disease (human, animals)
POlHL-197 17-02 0006 Response of the lung to injury -
Glycosaminoglycans and proteoglycans of the lung (human,
rats, hamsters)
MOD
POllll 1971/02 0008 Rejponw of the lung lo in|ury
Experimental models of lung disease
POIHL 19717-02 0010 Response of the lung lo in)uiy •
Proteoglycans in lung function and structure (hamsters)
POIHL 19717 02 0011 Response of the lung to injury
Physiological chaiacteri;ation of the elastase model
(hamsters)
POIHL 19717 02 0012 Response ol the lung to injury
Connective tissue biochemistry and enzyme injury ol the
lung (hamsters)
POIHL 1971702 0013 Response of the lung to injury
Handling of biologically active substances by the diseased
lung (guinea pigs)
POIHL 19717 02 0014 Response of the lung to injury
Stereology of epithelialized bronchi in evolving elastase
emphysema (hamsters)
POIHL 19717 02 0015 Response of the lung to injury -
Chronic bronchitis and emphysema (hamsters)
POIHL 19717 02 0016 Response of the lung to injury -
The alveolar macrophage in elastase emphysema (guinea
pigs, hamsters)
POlHL-19717-02 0019 Response of the lung to injury -
Animal model of fibrosing alveolitis (hamsters, guinea
pigs, rabbits)
' POlHL-19717-02 0020 Response of the lung to injury -
Recording of lung sounds in animal models of disease
(animals)
' POIHL 19717 02 0021 Response of the lung to injury -
Gallium lung scans in fibrosing alveolitis (hamsters)
POIHL 19717-02 0022 Response of the lung to injury
Localization of enzymes and sites of action in experimental
emphysema (hamsters)
POlHL-19717-02 0026 Response of the lung to injury ■
Protein depletion and postnatal lung development (rats)
POIHL 19717-02 0028 Response of the lung to injury
Compensatory growth of the lung following pneumonectomy
(rabbits)
POlHL-19717-02 0037 Response of the lung to injury ■
Catecholamines, prostaglandins and nucleotides in
pulmonary function (animals)
POlHL-197 17-02 0039 Response of the lung to injury ■
Lung scanning in alveolitis and asbestolic interstitial
pneumonia (human, animal)
POlHL-19717-02 0044 Response of the lung to injury ■
Lung sound analysis (human)
POlHL-19717-02 0045 Response of the lung to injury -
Ultrasound studies (human, hamsters)
ROlHL-19741-03 Murine CRD -A model of chronic
pulmonary inflammation (mice, rats)
ROlHL-19760-01 Cellular immune responses of the lung
(mice, guinea pigs)
ROlHL-19782-02 Pharmacologic studies on the ischemic
heart (dogs)
ROlHL-19825-02 Renin-volume interactions in coarctation
hypertension (dogs)
ROlHL-19873-03 Pulmonary responses to inhaled antigen
(rabbits, guinea pigs)
Vasodilators in experimental myocardial
Surgically induced myocardial edema
ROlHL-19937-02
infarction (dogs)
ROlHL-20080-02
(dogs)
ROlHL-20087-02 Developmental processes in pulmonary
hypertension (rats)
ROlHL-20163-02 Competitive coronary flow in native and
graft vessels (dog)
ROlHL-20170-02 Pulmonary infection in splenectomized
animals (mice)
ROlHL-20183-02 Portacaval shunt as treatment for
hyperlipemia (pigs)
ROlHL-20197-02 Maintenance and repair of vascular
endothelium (human, animals)
ROlHL-20199-02
in the rat
Drug-induced alterations in infarct size
Hypertension and vascular steroid
Cardiac bypass and coronary collateral
Probes of heart and nerve membranes-
Intravascular redistribution of blood
ROlHL-20201-01
receptors (rats)
ROlHL-20226-02
physiology (dogs)
ROlHL-20254-02
Fluorescent dyes
ROlHL-20371-02
volume (dogs)
ROlHL-20400-03 Diabetic neuropathy and peripheral
vascular diseases (human, hamsters)
ROlHL-20426-03 Myocardial function in diabetes mellitus
(dog, rat)
POlHL-20552-02 The development and regression of
cardiac hypertrophy
POlHL-20552-02 9001 The development and regression of
cardiac hypertrophy - Core A-Pathology
ROlHL-20572-02 Hemodynamic relations to metabolism in
hypertension
ROlHL-20572-02 0001 Hemodynamic relations to
metabolism in hypertension - Hemodynamic and myocardial
functional studies in the SHR (r,-t)
ROlHL-20572-02 0003 Hemodynamic relations to
metabolism in hypertension - Cardiac output and organ
blood flow in hypertension (rats)
POlHL-20592-02 0010 Cell biology oi cardiac and
skeletal muscle - Mitochondrial genesis during myocardial
cell hypertrophy and hyperplasia (rats)
ROlHL-20604-03 Sympathectomy-Cardiovascular and
molecular pharmacology (animals)
(contd)
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
MOD
348
MOD
ROlHL-206 10-02 Nerve growth factor and obstructive
cardiomyopathy (dogs)
ROlHL'20612-02 Chronic animal model of pulmonary
vascular injury (dogs)
ROlHL'20622-02 Pulmonary uptake and accumulation of
drugs (rabbits, rats)
ROlHL-20630-03 Development of a pulsed Doppler velocity
detector (human, animals)
ROlHL-2069002 Pulmonary hemodynamics in lung edema
during PEEP (dogs)
ROlHL-20719-02 Cold induced pulmonary hypertension
(cattle)
ROlHL-20725-02 Mechanisms and cellular functions of ion
transport
ROlHL-20768-02 Mechanisms of circulatory regulation in
heart failure (guinea pigs)
ROlHL-208 15-02 Validation of indirect tests of small
ain»ays function (human, dogs, ponies)
ROlHL-20827-02 Effects of hypertrophy on the coronary
circulation (dogs)
ROlHL-20829-02 Fluid mechanics of heart valve
prostheses (dogs, human)
ROlHL-20847-02 Respiratory neurochemical control
(human, goats)
ROlHL-20859-02 Beta adrenergic catecholamine receptor
ROlHL-20895-03 0006 Cineangiographic studies of
cardiovascular system - Cardiomyopathy -Hemodynamic,
radiologic, morphologic abnormalities (dog, rabbit)
ROlHL-20895-03 0007 Cineangiographic studies of
cardiovascular system - Determinants of collateral
formation (dogs, hamsters)
ROlHL-20895-03 0008 Cineangiographic studies of
cardiovascular system - Intercoronary anastomotic
circulation -Stenosis and occlusion (dogs)
ROlHL-20895-03 0010 Cineangiographic studies of
cardiovascular system - Cortical necrosis and acute renal
failure (human, dogs, rats, rabbits)
ROlHL-20912-02 Control on non-alpha chain synthesis in
thassemic mice
POlHL-20948-02 0003 Molecular basis of cholesterol
metabolism - LDL pathway in vivo (human, rats, guinea
pigs)
Hyperlipoproteinemia (rats, human)
Early events following stimulation of
Experimental lung abscess (rabbits)
Cellular mechanisms in cardiac
ROlHL-20954-02
ROlHL-20956-02
human platelets
ROlHL-20963-01
POlHL-20984-02
hypertrophy
POlHL-20984-02 0001 Cellular mechanisms in cardiac
hypertrophy - Contractile proteins in cardiac hypertrophy
(rabbits, calves)
POlHL-20984-02 0004 Cellular mechanisms in cardiac
hypertrophy - Myofibril accumulation in cardiac and
vascular muscle cells in hypertrophy
POlHL-20984-02 0006 Cellular mechanisms in cardiac
hypertrophy ■ Early biochemical aspects of cardiac
hypertrophy (rats)
POlHL-20984-02 9001 Cellular mechanisms in cardiac
hypertrophy - Animal models and preparation of contractile
proteins
POIHL-20993-02 Population dynamics of arterial cells in
atherogenesis
POlHL-20993-02 0001 Population dynamics of arterial
cells in atherogenesis - Arterial SMC population dynamics
in atherogenesis (swine)
POlHL-20993-02 0002 Population dynamics of arterial
cells in atherogenesis • Arterial endothelial dynamics in
atherogenesis (swine)
POlHL-2099302 0003
cells in atherogenesis •
(human, hares)
POlHL-20993-02 0004
cells in atherogenesis
Population dynamics of arterial
Clonal phenomena in atherogenesis
Population dynamics of arterial
Modifications of cholesterol balance
related to arterial cell divisions (swine)
POlHL-20993-02 0005 Population dynamics of arterial
cells in atherogenesis - Drugs other than hypolipidemic
drugs affecting atherosclerosis (swine, rabbits)
POlHL-20993-02 0006 Population dynamics of arterial
cells in atherogenesis - Mechanism of regression of
atherosclerosis by diet and injury (swine)
POlHL-20993-02 0008 Population dynamics of arterial
cells in atherogenesis - Angiotoxicity of cholesterol
oxidation in atherogenesis (rabbits)
POlHL-20993-02 0010 Population dynamics of arterial
cells in atherogenesis - Animal care and development and
standardization of animal models -Core
POlHL-20994-02 Dynamics of neutrophil elastase in the
lung
POlHL-20994-02 0001 Dynamics of neutrophil elastase in
the lung - Dynamics of neutrophil elastase in normal
animals (dogs, rabbits)
POlHL-20994-02 0003 Dynamics of neutrophil elastase in
the lung Neutrophil elastase flux in models of lung
disease (dogs)
POlHL-20994-02 0005 Dynamics of neutrophil elastase in
the lung - Protease inhibitors in pulmonary inflammation
and emphysema (rabbits)
POlHL-20994-02 0007 Dynamics of neutrophil elastase in
the lung - The etiology of experimental emphysema (dogs)
POlHL-20994-02 0008 Dynamics of neutrophil elastase in
the lung • Structure-function correlation in experimental
emphysema (human, dogs)
POlHL-209 94-02 0009 Dynamics of neutrophil elastase in
the lung - Biosynthesis and degradation of elastin in
emphysema (human, hamsters)
ROlHL-21008-02 Effect of pollutants on organotypic lung
cultures (rats)
R23HL-21051-02 Adrenergic receptors and the adenylate
cyclase system (frog RBC)
ROlHL-21071-02 Mechanisms of hypertension in
coarctation of the aorta (dog)
ROlHL-21076-02 Lung fluid, protein exchange after
hemorrhagic shock (sheep)
ROlHL-21099-02 Subcellular changes of blood vessels in
hypertension (rats)
ROlHL-21103-01 Parametric mechanical studies of
hypertensive arteries (dogs, rats)
R01HL-2U05-02 Organ specific drugs -Cardiovascular and
renal effects (dogs)
R23HL-21 116-02 Mechanisms of membrane and tissue
damage in lung (dogs, rabbits)
R23HL-2 1134-02 Immune function and fibrogenesis in
silicosis (guinea pigs)
ROlHL-21156-02 Antitrypsin and other causes of chronic
lung disease
R23HL-21 167-02 The electrophysiology of cardiac
hypertrophy (rats)
ROlHL-21 176-02 Phospholipid exchange proteins in lung
tissue (lambs)
R23HL-21203-02 Effect of vasoactive agents on left-to-
right shunts (lambs)
R23HL-21213-G1 A model for calcium homeostasis in
excitable tissue (marine worms)
R23HL-21234-02 The regulation of cardiac hypertrophy
(rabbits)
ROlHL-21257-02 Breathing in sleep-Airway control and
blood gases (cats)
ROlHL-21260-02 Risk factor relationships of
atherosclerosis (monkeys)
ROlHL-21272-02 Sodium homeostasis and renal
prostaglandins (dogs)
R23HL-21298-02 Coronary vasomotion (dogs, pigs)
R23HL-21327-02 Molecular mechanisms of chemical
myocardiopathies (rats)
ROlHL-21394-02 Pulmonary angiotensin-converting enzyme
(rabbits)
ROlHL-21416-02
diabetes mellitus
ROlHL-21418-02
ROlHL-2 15 00-02
stress (dogs)
POlHL-21584-02 0004
and abnormal states
mechanics (dogs)
ROlHL-21592-01 Lipoproteins and coagulation factors in
atherosclerosis (pigeons)
ROlHL-2153202 Development of a transcutaneous power
transfer system (cattle)
R23HL-2 1663-01 Regulation of collagen biosynthesis
(chick, embryo)
ROlHL-21697-01 Myocardium infarct sizing by 82Rb
emission tomography (dogs, human)
ROlHL-21735-01 Electrophysiology after healed myocardial
infarction (cats)
Thallium and antimyosin in
In vitro models of ischemia and
Atherosclerosis in new modles of
Experimental myocardial infarction (rats)
Performance of respiratory muscles under
Respiratory mechanics in normal
Effects of anesthesia on respiratory
Thallium and antimyosin in
Canine models of ischemia and
ROlHL-21751-02 0001
ischemia and infarction
infarction (rats, mice)
ROlHL-21751-02 0002
ischemia and infarction
infarction
ROlHL-21756-11 Vascular disease-Cytochemistry and
ultrastructure (human, rats, mice, hamsters)
ROlHL-21779-01 Steroids in adrenal regeneration
hypertension (rats)
ROlHL-21796-01 Applied pulsatile hemodynamics in
vascular surgery (dogs)
R01HL-21820-01 Regulatory role of myosin in cardiac
hypertrophy (dogs)
ROlHL-21829-01 Etiology of obstructive airway disease in
children (also monkeys)
ROlHL-2187201 Myocardial perfusion in the hypertrophied
heart (dogs)
ROIHL-219 12-01 Biosynthesis of lipoic acid and
atherosclerosis (birds, chick embryos)
R23HL-219 18-01 Hypersensitivity pneumonitis in guinea
pigs
R23HL-21973-01 Catecholamine metabolism and the heart
(human, guinea pigs)
R23HL-21997-01 Pulmonary immunopathology in the
compromised host (guinea pigs)
ROlHL-22005-01 Intermittent retroperfusion of ischemic
myocardium (dogs)
ROlHL-22008-01 Left ventrivular calcium content and
contractility (rats)
R23HL-22011-01 Adrenergic receptor cyclase system in
sensitized lung (rats, guinea pigs)
ROlHL-22069-02 Experimental renal arterial hypertension
(dogs)
ROlHL-22098-01 Is postoperative infarction due to
reperfusion injury? (human, dogs)
ROlHL-22152-02 Ventricular dysfunction and cardiac
surgery (dogs)
ROlHL-221 78-01 Lung airway properties by acoustic
impulse reflection
ROlHL-22216-02 Vascular mechanisms in renal
hypertension (dogs)
ROlHL'22274-01 Quantitating in series effects in cardiac
arrhythmias (dogs)
ROlHL-22301-01 Immunogenetics of chronic pulmonary
inflammation (mice)
ROlHL-22306-01 Renal catecholamines- Pathophysiology
of hypertension (dogs)
ROlHL-22327-01 Transport of arterial blood gases through
skin (swine)
ROlHL-22367-01 Estrogen receptors in very low density
lipoproteins (chicken livers)
ROlHL-22411-01 Neuroendocrine involvement in
hypertension (rats)
R23HL-22438-01 The etiology of genetic hypertension
(rats)
ROlHL-22446-01 Chemical and functional studies of low
copper in lung (pigs)
R23HL-22448-01 Modulation of heart graft antigenicity by
perfusion (rats)
ROlHL-22470-01 Liposome myocardial uptake in infarct
and ischemia (dogs, rats, mice)
ROlHL-22546-02 Baroreceptor reflex mechanisms in man
ROlHL-22550-02 Genetic cardiomyopathies in salamanders
and hamsters
ROlHL-22562-02 Mechanism of cardiac action potential
propagation (tunicates)
ROIHL-22563-02 Prostaglandins, the kidney and
hypertension (rats)
ROlHL-22573-01 Treatment of post surgical
vasoconstriction (dogs, monkeys, human, rats)
R23HL-22575'01 Factors modifying cardiac digoxin effects
and content (dogs, cats)
POlHL-22602-01 0004 Pathophysiology of the
endothelium - Endothelium, platelets smooth muscle and
atherosclerosis (rabbits)
P01HL-22e 19-01 9001 Cellular mechanisms of heart
failure - Experimental pathological models core
ROlHL-22661-01 Chronic total cardiopulhonary mechanical
substitution (sheep)
ROlHL-22664-01 Regulation of myocardial cell growth
(rats, guinea pigs)
ROlHL-22671-01 Removal of senescent and stored human
red cells
R01HL-22676-01 Pathogenesis in experimental Interstitial
pneumonitis (rabbits)
ROlHL-22718-01 Cardiovascular drug interactions-
Metabolism models (dogs)
' ROlHL-22767-01 Model system for cardiac action
potentials (squid, axons)
R23HL-22775-01 Muscarinic receptors in the developing
heart (chick embryo)
ROlHL-22783-01 Hemodynamic induction of intimal
fibromuscular lesion
ROlHL-22784-01 Ductus arteriosus closure-An arterial
lesion model (rabbits)
ROlHL-2280101
(dogs)
■ R01HL-22836-01
(rats)
ROlHL-22894-01 Two dimensional ultrasound and cardiac
surgery (human, dogs)
ROlHL-22977-01 Role of vasoconstrictor mechanisms in
heart failure (human, dogs)
ROlHL-23171-01 Coronary collateral circulation in
myocardial ischemia (dog, pig, rat, human)
ROlHL-23224-01 Hypoxia and pulmonary vascular smooth
muscle (rat, cat)
P60HL-23282-01 0001 Comprehensive hospital/community
sickle cell center - Fetoscopy for intrauterine diagnosis of
hemoglobinopathy (human, monkeys)
ROlHL-23586-06 Pharmacologic control of hypersensitivity
phenomena (human)
ROlHL-23587-01 Phosphorylation of myocardial protein
(guinea pigs)
ROlHL-23595-01 Experimental emphysema-Depression of
protease inhibitors (rats, hamsters)
ROlHL-23602-01 Physiology of renin, aldosterone and
prostaglandin (human, rats, dogs)
ROlHL-23603-01
disease (rats)
ROlHL-23653-01
Analysis of coronary artery behavior
The spontaneously hypertensive kidney
Morphogenesis of hypertensive vascular
Protection of the ischemic myocardium
Effects of digoxin therapy in newborn
(dogs)
ROlHL-23980-01
and adult sheep
NOlHR-62901-04 Measure pulmonary function in infants
and children (also dogs, rabbits)
NOlHV-53029-04 Nonhuman primate models of
atherosclerosis
NOlHV-53030-05 Nonhuman primate models of
atherosclerosis and hypertension
NOlHV-53031-04 Nonhuman primate models of
atherosclerosis and hypertension
NOlHV-62905-02 Non-human primate models of
arteriosclerosis
NOlHV-72925-04 Non-invasive detection of atherosclerotic
lesions (human, monkeys, dogs)
NOlHV-72933-01 Electrical energy transmission technique
development (dogs)
NOlHV-72978-02
NOlHV-72980-02
Development of models of hypertension
Development of models of hypertension
(contd)
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
••Oriented significantly to above subject.
M Grant has subprojects describing specihc research aspects.
See Appendix for investigator's name and grant number.
AODELS, CHEMICAL
SEE Also ENZYME MODELS
ROIHL 0283b 21 Renal liansport camei lor oiganic
compounds (do|s. rats)
R01HL05bb6 19 Proteins, lipoproteins Structure and
reactivity (chicken, human, diving mammals)
P01HL06285 18 0173 Cardiovascular respiratory
physiology and biochemistry Skeletal and cardiac muscle
(unction
PO1HL06285 18 0199 Cardiovascular respiratory
physiology and biochemistry Renal tubular reabsoiption o(
sodium chloride (hamsters, rabbits)
P01HL06314 U OOSO Immunologic mechanisms in
cardiovascular disease Physiologic changes in
lymphocytes (human, mice)
ROIHL 09739 13 Biophysical studies o( proteins (human)
ROIHL 10894 12 Intestinal bacteria and steroid
metabolism (human, guinea pigs, rabbits, rats)
ROIHL 12395 10 Xray study of oxygen-carrying cobalt
complexes
ROIHL 1252609 Raman spectra ot heme proteins and
related molecules
ROIHL 13157 09 Molecular oxygen carriers Synthesis.
structure, bonding
ROlHL-13164-07 Interaction of the alpha and beta chains
of human hemoglobin
ROlHL-13399-16 Heme protein structure and function
(human, horse, plants, bacteria)
R01HL1358111 Reactions of oxygen with heme proteins
ROIHL 1365208 Metal sites in metalloproteins
(mushroom)
R01HL141 11-07 Cholesteryl esters in membranes and
atherosclerosis (human, swine)
** P50HL-14147-08 0014 Specialized center of research in
thrombosis Theoretical models for electrostatic effects in
blood clot formation
P50HL14237-07 0003 Support for arteriosclerosis center
- Structure of lipoproteins and apolipoproteins (human,
rabbits)
ROlHL-14680-07 Specific enrichment of myoglobins for
carbon 13 NMR (catacea)
ROlHL-1515505 Rheology of pulmonary secretions (dogs)
ROlHL-1529307 Sickle cell hemoglobin -Interactions and
aggregation (human)
** R01HL15640-06 Thermodynamic studies on model oxygen
carriers
P01HL15835-06 0006 Study of muscles related to heart
disease ■ Ultrastructural and chemical studies of muscle
(animals)
ROlHL-15958-06 X-ray diffraction analysis of thrombin
and neurotoxin
** R01HL16087-05 Structural and dynamic study of model
heme complexes (yeast)
P01HL16607-05 0001 Calcium ion and control of
cardiovascular function ■ Bilayer lipid membranes,
antibiotic probes, and SR function
R01HL16860-05 Mossbauer studies of respiratory
hemoproteins
ROlHL-18253-03 Structure of the palytoxins
ROlHL-18623-12 Physical chemistry of biologically active
lipids (bacteria, plant, cattle, human)
** ROlHL-19514-03 Proteinase inhibitor model with clinical
potential
ROlHL-20073-02 Blood compatible materials by fluid
perfusion (human, dogs)
ROlHL-22771-01 Thrombogenic phospholipid surfaces
(cattle)
ROlHL-23598-01 Dietary (at. cholesterol and bile acid
turnover (rats)
MODELS, MATHEAAATICAL
SEE ALSO COMPUTER SIMUUTION
ROlHL-02888-22 Interrelationships of circulation and
respiration (opossum, cats)
POlHL-06285-18 0210 Cardiovascular-respiratory
physiology and biochemistry - Physicochemical and
enzymatic studies of lung surfactant (Halobacterium)
R01HL07575-15 Analysis of time-coherent cardiovascular
data
POlHL-07896-15 0036 Environmental biomedical research
program - Respiratory heat loss in deep diving (infants,
dogs)
ROlHL-0835914 li/lorphopharmacology of vascular
adrenergic transmission (rabbits, rats)
POlHL-08805-15 0044 Regulation of ventilation and
pulmonary circulation - Neurochemical Interactions in
respiratory control (human, dogs, goats)
POlHL-08805-15 0045 Regulation of ventilation and
pulmonary circulation - Integrated description of
neurochemical respiratory control system
P01HL08899-14 0020 Tolerance to respiratory gases in
health and disease - Oxygen tolerance (human, rats,
guinea pigs)
P01HL-08974-I4 0028 Natural and experimental
atherosclerosis - Geographic pathology of atherosclerosis
and coronary heart disease (human)
** POlHL-0901115 0012 A research and resource program
in blood - Theoretical population genetics (human)
POlHL-09011-15 0017 A research and resource program
in blood - Operations research laboratory
R01HL09610-14 Control of cholesterol metabolism -Bile
acid transport
M
349
ROIHL 10330 II Physiological mechanics of the heart nnd
arteries (dogs, rabbits, horses)
ROlHt 10417 12 Multiple systems in electrocardiography
(human)
POIHL 11307 12 0002 Biophysical studies in pediatric
caidiology Cardiac extracellular eleclrophysiology (human,
dog, chimpanzee)
POIHL 11307 12 0003 Biophysical studies in pediatric
cardiology Cellular biophysics (animals)
POIHL 11307 12 9001 Biophysical studies in pediatric
cardiology Core support computer science
POIHL 11307 12 9002 Biophysical studies in pediatric
cardiology Biomedical engineering
POIHL 11310 12 0054 Mechanisms o( cardiovascular
disease Mathematical model of ventricular pressure-
volume (human, dogs)
POIHL 11310 12 0056 Mechanisms of cardiovascular
disease Cardiac output response to blood pressure
reduction in infants (human)
POIHL 113 1012 0057 Mechanisms of cardiovascular
disease Blood pressure reduction after heart surgery in
adults (human)
P01HL1131012 0069 Mechanisms of cardiovascular
disease - Factors affecting mortality and morbidity after
heart surgery (human)
POIHL 11310 12 0070 Mechanisms of cardiovascular
disease Factors affecting longterm mortality and
morbidity after heart surgery (human)
POIHL 11310-12 0087 Mechanisms of cardiovascular
disease Electrophysiology and electropharmacology of the
heart (dogs)
POlHL-11351-12 0013 Cellular and molecular
mechanisms of myocardial function Ion exchange in the
perfused septum high-resolution technique (rabbits, rats)
POlHL-1 1678-11 Cardiovascular dynamics and their
control
POlHL-1 1678-11 0009 Cardiovascular dynamics and their
control ■ Control of respiration (cat, human)
POlHL-1 1678-11 0017 Cardiovascular dynamics and their
control Overall control of circulation -Mathematical
analyses
POIHLI 1678-11 0064 Cardiovascular dynamics and their
control - Renal medulla-Control of renal hemodynamics,
electrolyte excretion (dogs)
POIHL 1167811 9001 Cardiovascular dynamics and their
control • Core -Computer services
' ROlHL-1182210 Biophysical studies of macromolecular
interactions (microorganism, human)
ROlHL-11906-11 Comparative study of heart function
(cats. rats, hedgehogs, squirrels)
ROlHL-1 19 19-08 Pulmonary circulation in surgical heart
disease (human, dogs)
P01HL121 57-11 0054 Functions and mechanisms of cell
membrane ion transport - Simulation of electrogenic ion
transport in cardiac muscle
ROlHL-12174-11 Ventilation/perfusion distribution in the
lung (human, mammals)
ROlHL-12494-10 Continuum mechanics in biophysics
(human, animals)
ROlHL-12607-10 Dynamics of pulsatile blood flow (human,
dogs, rats)
* ROlHL-12711-09 Mathematical approach to cardiovascular
mechanics (human, animals)
ROlHL-1282009 In vitro regulation of prothrombin
activation
ROlHL-12879-09 Pulmonary transport and metabolism in
vivo
Pulmonary transport and
Osmotic compartmental model of
ROlHL-12879-09 0002
metabolism in vivo
barrior exchange
R01HL12879-09 0008
metabolism in vivo
measurements
R01HL12879-09 0011
metabolism in vivo
Pulmonary transport and
Stop-flow technique for permeability
Central neural control of cardiovascular
Cardiorespiratory control in exercise
Intrarenal pressure and renal function
Pulmonary transport and
Membrane characteristics of lung
cells (human, animals)
ROlHL-12974-10 Tracer kinetics, flows and masses in
body organs (human, dogs)
R01HL13187-09
function (cats)
ROlHL-13233-08
(human)
ROlHL-13323-08
(human, dogs)
POIHL- 133 30-08 0031 Mechanical circulatory support ■
Hemodynamics of cardiac prosthesis
R01HL13596-07 Clearance of plasma proteins from
alveoli
ROlHL-13803-07 Advanced cardiac valvular and vascular
prosthesis (dogs, baboons)
ROlHL-13824-06 Defense mechanisms in pathogenesis of
emphysema (human, dogs)
P50HL14138-05 0016 Center for research on
atherosclerosis - Computer analysis of angiograms
P50HL-14147-08 0013 Specialized center of research in
thrombosis - Mathematical models of blood coagulation
kinetics
P50HL-142 14-07 0033 Newborn lung center for hyaline
membrane disease • Statistical modeling, predictive
classification in clinical management of HMD
MOD
POIHL 14388 0/ 0214 Regulation of the circulation in
pathological stales Defoimslion pattern and sires*
analysis of the left ventricle
POIHl 14388 07 0215 Regulation of the circulation in
pathological slates Left ventricle model m
pathophysiologic stales
POIHL 14388 0/ 0217 Regulation of the circulation in
pathological stales Fluid mechanics of aortic flow (dogs,
human)
POIHL 14414 07 0003 Environmental influences on
cardiorespiratory and cellular functions Exposure to
abnormal gaseous environments (human, dogs, rabbits)
ROIHL 14495 05 Solid and structural mechanics of lungs
(mammals)
POIHL 1458007 0001 Program project in respiratory
mechanics Micromechanics of the lung (dogs, rats)
POIHL 1458007 0002 Program project in respiratory
mechanics Airway aerodynamics (human, dogs)
P01HL1458007 0005 Program project in respiratory
mechanics Development and evaluation of tests of
pulmonary function (human)
R01HL14614 07 Voltage control of contraction in heart
(sheep)
■ ROIHL 14651-05
(dogs, rats)
ROlHL-14700 05
role in obstructive disease (human)
P01HL15194 07
dysfunction
ROlHL-1537806
prostaglandins
■ R01HL1562205
dogs)
ROlHL-15655-05
Mechanical behavior of left ventricle
Humoral and lung proteaseantiprotease
disease (human)
Pathophysiology of cardiopulmonary
Ultrastructure of antihypertensive
Computer simulation in cardiology (rats.
Blood flow and gas exchange in placenta
and lungs (sheep) rabbits)
ROlHL-15698-12 Factors affecting the action of
anticoagulants (rats, human)
P01HL-15832-06 0005 Chemical-structural predispositions
to lung injury Pulmonary structure and stress-strain
relationships (rats)
ROlHL-16325-03 Breathing patterns in man
R01HL16580-04 Mathematical models for studying sickle-
cell disease
POlHL-16851-04 0003 Human red cell membrane in
health and disease - Modeling membrane mechanics and
blood rheology
POlHL-1691005 0005 Regulation of the peripheral
circulation - Control of circulation by baroreceptor and
chemoreceptor reflexes (dog, monkey)
ROlHL-16916-04 0001 The role of albumins in lung water
accumulation - Capillary permeability (dogs, human)
ROlHL-1692105 Synthetic hydrogels as blood tolerable
materials
POlHL-1742105 0001 Regulation and exchange in the
microcirculation - Mass transfer and microcirculatory
function (rats)
POlHL-17421-05 0002 Regulation and exchange in the
microcirculation - Metabolic and myogenic blood flow
regulation in microcirculation (animals)
P01HL17421-05 0004 Regulation and exchange in the
microcirculation - Localization of flow regulation in the
microcirculation (cats, human)
ROlHL-1745204 Depolarization induced cardiac
automaticity (human, animals)
ROlHL-1751703 Arterial wall oxygen transport in
atherosclerosis (rabbits, dogs)
ROlHL-17623-05 Initial events in thrombus formation on
surfaces (human, rats)
P50HL-17646-04 0005 Study of ischemic heart disease ■
Biochemical markers and mediators of myocardial ischemic
injury
P50HL17646-04 0006 Study of ischemic heart disease -
Mathematical models for predicting infarct size using CPK
and other markers
P50HL-17651-04 0039 Ischemic heart disease specialized
center of research - Measurement and prediction of infarct
size (human, dog)
P50HL-17667-04 0041 Study of ischemic heart disease -
Biophysical sciences core-Data collection and retrieval
POlHL-17731-04 0007 Physiological basis of pulmonary
disease - Theoretical gas exchange
POlHL-17731-04 0010 Physiological basis of pulmonary
disease ■ Gas exchange kinetics (dogs)
POlHL-17813-04 0001 Lung disease and the oxygenation
of blood and tissue - Diffuse interstitial lung disease-
Pathophysiology (human, dogs)
■ ROlHL-17859-04 Computational methods in cardiac fluid
dynamics
ROlHL-17998-04 Regulatory mechanisms in blood
circulation (dogs)
■ ROlHL-18022-03 Role of multicomponent diffusion in gas
exchange (avian eggs)
ROlHL-1804004 Waveform dependency in defibrillation
(calves)
ROlHL-18145-03 Oxygen transport mechanisms in hypoxia
(dogs, rats, rabbits)
P50HL-18323-04 0042 SCOR hypertension center Blood
viscosity and blood volume in hypertensive disease
(human, dog)
ROlHL-18426-04 Regulation of renal hemodynamics (dogs)
ROlHL-18630-03 Pulmonary hemodynamics in atelectasis
and hypoxia (dogs)
(contd)
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
•*Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
MOD
350
MOL
Protein transport through arterial tissue
Ventricular mechanics In the overloaded
Mechanics of heart muscle contraction
Computer technology for transaxial
Vagal control of heart rate--A biophysical
Heterogeneity of regional myocardial
Aerosol therapy (models, dogs, human)
Aerosol growth In the respiratory system
ROlHL-18736-03
(rabbits)
ROlHL-18749-03
heart (dogs)
R01HL18912-03
(cats, dogs)
ROlHL-18968-03
tomography
ROlHL-1907603
model (rabbits)
ROlHL-19135-04
blood flow (dogs)
ROlHL-1913903 Dispersion of diffusible Indicators In the
body (human, cats, dogs)
P50HL-1915302 0004 SCOR -Pulmonary edemas-Eitology,
pathogenesis - Physical mechanisms In lung transvascular
transport-Math models (sheep)
P50HL-19153-02 0005 SCOR-Pulmonary edemas-Eitology,
pathogenesis - Lung vascular permeability measured by
indicator dilution methods (sheep)
P50HL-19153-02 0008 SCOR-Pulmonary edemas-Eitology,
pathogenesis - Core-Blomedical engineering
ROlHL'19173-03 Analysis of blood trauma from
microporous oxygenators (human, dogs, rabbits)
ROlHL-19248-03 Breathing pattern variation and
mechanical Influences
ROlHL-1929803 Pulmonary hemodynamics (dogs, cats)
ROlHL-19350-02 Prevention of thrombosis by applied
electric fields (sheep)
ROlHL-19370-03 Coronary capillary exchange-The effects
of Ischemia (dogs, sheep)
ROlHL-19454-02 Rheological factors In transport across
arterial wall (dogs)
ROlHL-19460-03 Mechanics of the papillary muscle and
the left ventricle (cats, rabbits)
ROlHL-19487-03 Cardiac actions of digitalis (dogs, cats)
ROlHL-19700-03 Deposition of hygroscopic aerosols
(models)
' ROlHL-19704-03
ROlHL-19722-03
(models)
POlHL-19737-02 0005 Cellular and molecular aspects of
respiratory physiology - Interaction of respiratory exchanges
and blood gas parameters (human, animals)
POlHL-1973702 0010 Cellular and molecular aspects of
respiratory physiology - Effects of pulsatile flow and volume
on capillary exchanges (dogs, rats)
' ROlHL-19824-02 Mass transfer in the microcirculation
ROlHL-19946-03 Reduction of iron overload in
thalassemia (children, rabbits, dogs, monkeys)
ROlHL-20080-02 Surgically Induced myocardial edema
(dogs)
ROlHL-20105-02 Deposition of hygroscopic aerosols in
bronchi (dogs, human, models)
ROlHL-2027302 Cardiac fiber direction and the QRS
complex (dogs)
POlHL-20552-02 9002 The development and regression of
cardiac hypertrophy Core B -Blomathematics
' POlHL-20592-02 0004 Cell biology of cardiac and
skeletal muscle - Excitation, conduction and contraction -
Modelling in Purkinje fibers
ROlHL-20829-02 Fluid mechanics of heart valve
prostheses (dogs, human)
ROlHL-20847-02 Respiratory neurochemical control
(human, goats)
ROlHL-21052-01 Evaluation of a digitalis therapy advisor
R23HL-21 168-01 Hypoxemic respiratory failure -Physiologic
evaluation (human, dogs)
ROlHL-21188-02 Pulsatory water flux and endothelial cell
desquamation
R23HL-21 197-02
relaxation (dogs)
R01HL-2I435-02 Control, cardiovascular and renal effects
of potassium (dogs)
' R23HL-2146202 Mechanical Interactions between ventricle
arteries (dogs)
' ROlHL-21483-01 Electronic, thermodynamic and kinetics
of hemoglobin
POlHL-2158402 0001 Respiratory mechanics in normal
and abnormal states - Engineering analysis of lung
deformation (human, animals)
■ ROlHL-21672-01 Antiarrhythmic drug action on VMAZ of
cardiac cells
ROlHL-21796-01 Applied pulsatile hemodynamics in
vascular surgery (dogs)
• R23HL-21855-01
human lung
ROlHL-221 18-02
mellitus
ROlHL-22136-02
ROlHL-2215202
surgery (dogs)
ROlHL-22201-01
Right ventricular contraction and
Mathematical models of branching In the
Microcirculation in patients with diabetes
Histamine and cardiac adenyl cyclase
Ventricular dysfunction and cardiac
Pharmacology and chemistry of
nudibranch toxins (guinea pigs, rats, mice)
The cardiopulmonary junction (dogs.
Mechanism of cardiac pacemaking
ROlHL-22223-01
models)
ROIHL-22235-01
(rabbits)
ROlHL-22265-02 Isozymes of heart glutamate aspartate
transaminase (swine, ducks)
ROlHL-22313-01 Lung elastic recoil -Age and disease
(human)
Non-Invasive system for arteriosclerosis
Analysis of coronary artery behavior
ROlHL-2232701 Transport of arterial blood gases through
skin (swine)
ROlHL-2240201 Heparin-biophysical, chemical and
biological aspects (mice, human)
ROlHL-22562-02 Mechanism of cardiac action potential
propagation (tunicates)
ROlHL-22569-02 Intestinal secretion -Capillary and tissue
forces (dogs, cats)
ROlHL-22604-01
studies (human)
ROlHL-22801-01
(dogs)
R23HL-22933-01 Transvascular fluid and protein exchange
in the lung (sheep)
ROlHL-22955-01 Inetlcs of prothrombin activation
" R23HL-22975-01 Dynamics of autoregulatlon of muscle
blood flow (dogs)
ROlHL-22976-01 Nonuniform ventilation and diffusing
capacity (human)
ROlHL-22980-01 Kinetic and mechanistic studies of blood
coagulation (human, cattle)
** ROlHL-23194-02 Genetics of hypertension and associated
variables (human)
** ROlHL-23615-01 Biochemistry of contractile proteins
(chicken, rabbit)
ROlHL-23982-01 Control of coronary flow by carbon
dioxide tension (dogs)
ROlHL-23983-01 Quantitative radiocardiography (human,
dogs)
NOlHR-62901-04 Measure pulmonary function in infants
and children (also dogs, rabbits)
MODELS, PHANTOM
POlHL-07293-17 0050 Non-invasive cardiovascular
measurements - Cardiac dimensions measurements
engineering evaluation and error analysis
POlHL-07293-17 0051 Non-Invasive cardiovascular
measurements - Physiologic evaluation of duplex scanner
(dogs)
** ROlHL-12083-11 Flow field in aorta and its major
branches (dogs, phantom models)
" ROlHL-15722-06 Hemorrheology studies related to In vivo
blood flow (human)
ROlHL-18156-02 Hemodynamics In curved arteries
ROlHL-18969-02 Arterial wall oxygenation (rabbits, dogs)
POlHL-1971702 0046 Response of the lung to Injury ■
Bioengineering section
ROlHL-21697-01 Myocardium Infarct sizing by 82Rb
emission tomography (dogs, human)
ROlHL-22080-01 Phosphorus NMR studies on cardiac
tissue (rats, rabbits)
** ROlHL-22223-01 The cardiopulmonary junction (dogs,
models)
NOlHV-52966-01 Development and evaluation of an
ultrasonic Imaging system (swine)
** NOlHV-62969-03 Cardiology patient simulator evaluation
NOlHV-72930-02 Atherosclerosis assessment-Angiography
and ultrasound (dogs, human)
NOlHV-72931-02 Non-invasive detection of atherosclerotic
lesions (human, dogs)
NOlHV-72932-00 Non-Invasive detection of atherosclerotic
lesions (human, phantoms)
MOLECULAR BASIS OF NEOPLASTIC DISEASE
SEE NEOPLASMS CHARACTERISTICS, MOLECULAR LEVEL
STUDIES
MOLECULAR BIOLOGY
SEE ALSO NEOPUSMS CHARACTERISTICS, MOLECULAR LEVEL
STUDIES
POlHL-031 74-23 0010 Mechanisms of acute vascular
reaction to injury - Search for mutagens in the human
blood (bacteria, animals)
POlHL-06285-18 0173 Cardiovascular-respiratory
physiology and biochemistry - Skeletal and cardiac muscle
function
POlHL-06285-18 0193 Cardiovascular-respiratory
physiology and biochemistry - Hormonal regulation of
sodium transport-Aldosterone (rats, toads)
POlHL-06285-18 0194 Cardiovascular-respiratory
physiology and biochemistry - Hormonal regulation of
sodium transport -RNA synthesis (rats, toads)
POlHL-06285-18 0195 Cardiovascular-respiratory
physiology and biochemistry - Thyroid thermogenesis and
sodium transport (rats)
POlHL-06285-18 0196 Cardiovascular-respiratory
physiology and biochemistry - Hormonal regulation of
sodium transport-Epithelial cell membranes (toads)
** POlHL-06285-18 0215 Cardiovascular-respiratory
physiology and biochemistry - Conformation of biopolymers
ROlHL-08299-16 Molecular biology of hemerythrin and
hemocyanin (invertebrates)
** POlHL-1135112 0004 Cellular and molecular
mechanisms of myocardial function - Molecular
mechanisms of contractile function and differentiation
(animals)
POIHLI 1351-12 0006 Cellular and molecular
mechanisms of myocardial function - Molecular physiology
and energetics of muscle (frogs)
POlHL-11351-12 0019 Cellular and molecular
mechanisms of myocardial function - Mechano-chemical
kinetics of small perturbations
R01HL-15e92-07 Force and speed in skeletal and cardiac
muscle
ROlHL-15696-06 Mechanism and role of cyclic GMP In
heart (animals)
P01HL15835-06 0006 Study of muscles related to heart
disease - Ultrastructural and chemical studies of muscle
(animals)
POlHL-15835-06 0007 Study of muscles related to heart
disease - Structure and function of Limulus striated and
cardiac muscle
ROlHL-16037-06 Molecular properties of cardiac
adrenergic receptors
POIHL 16137-05 0008 Alveolar biology - Macromolecular
events in pulmonary cells in toxic environments (animals)
ROlHL-16152-06 Electrophysiology of neonatal to adult
heart (cats, frogs, guinea pigs)
P01HL-164I1-04 Blood systems in coagulation and vessel
disease
POlHL-16411-04 0001 Blood systems In coagulation and
vessel disease - Molecular studies of the role of
complement in blood coagulation (human, rabbits)
POlHL-16411-04 0003 Blood systems in coagulation and
vessel disease - Molecular events involving the late stages
of coagulation (rabbits)
POlHL'16411-04 0006 Blood systems In coagulation and
vessel disease Factor VII -Immunochemistry and
immunobiology (human, mice)
POlHL-16683-04 0001 Function and growth of cardiac
and skeletal muscle - Light chains of the skeletal and
cardiac myosin molecule (rabbits, frogs)
P01HL16683-04 0002 Function and growth of cardiac
and skeletal muscle - Myosin, actio, ATP, interaction in
solution
POlHL-1685104 0006 Human red cell membrane In
health and disease - Hexose transport and erythrocyte
membrane proteins (human)
ROlHL-18519-03 Albumin, endothelium and
hemocompatibility (human, dog, cattle, rabbit)
' POlHL-18576-03 0002 Thrombosis research program
project - Molecular basis of fibrin formation (human, cattle,
lamprey)
POlHL-18577-03 Lipoproteins -Cell surface interactions
POlHL-18577-03 0001 Lipoproteins -Cell surface
interactions - Structural studies of serum lipoproteins in
man and dogs
P01HL18577-03 0003 Lipoproteins-Cell surface
interactions - Mechanism of lipid exchange in lipoproteins
and cell membranes
POlHL-1857703 0004 Lipoproteins -Cell surface
interactions - Analysis and chemical modification of
proteins In lipid transport (human, dogs)
POlHL-18708-03 Oxygen, energy and contractility in
cardiac tissue
POlHL-18708-03 0003 Oxygen, energy and contractility in
cardiac tissue - Structural-functional studies on cytochrome
c oxidase
* POlHL-18708-03 0004 Oxygen, energy and contractility in
cardiac tissue - Structural-functional studies on
sarcoplasmic reticulum (rabbits)
P01HL18708-03 0005 Oxygen, energy and contractility in
cardiac tissue - Cytosolic calcium homeostasis and
bioenergetics of cardiac tissue (animals)
POlHL-18708-03 0007 Oxygen, energy and contractility In
cardiac tissue - Surfaces, energy requirements, and
contractile proteins of cardiac cell in vitro
POlHL-18708-03 0010 Oxygen, energy and contractility In
cardiac tissue - Tissue oxygen utilization (rats, dogs)
ROlHL-19423-03 Catecholamine action on the heart (cats,
rats)
ROlHL-19455-03 Role of endothelial cells in vascular
permeability (tissue culture)
R01HL19653-03 Circulatory system effects of angiotensin
analogs (rats)
ROlHL-20262-02 Cardiac glycosides and the mechanism
of the sodium-potassium pump
ROlHL-20339-02 Vascular alpha-adrenergic receptor
molecular properties
ROlHL-20365-03 Molecular mechanisms of anion transport
* POlHL-20592-02 0001 Cell biology of cardiac and
skeletal muscle - Molecular mechanism of muscle
contraction (animals)
POlHL-20984-02 0002 Cellular mechanisms in cardiac
hypertrophy - Thermodynamic, fluorescence, chemical
modification of hypertrophied heart myosin
R23HL-21051-02 Adrenergic receptors and the adenylate
cyclase system (frog RBC)
* ROlHL-21 139-02 Molecular biology of factor XIII (human)
ROlHL-21140-01 Studies of pulmonay alveolar
macrophage function (rabbits)
* ROlHL-21342-02 Isolation and analysis of sodium channel
from heart (frogs)
ROlHL-22040-01 Regulation of lysyl-cross-linklng in
vascular tissue (rats, turkeys)
ROlHL-22239-01 The molecular basis of electrical
excitability (chick embryos, rats)
I POlHL-22619-01 Cellular mechanisms of heart failure
* POlHL-22619-01 0001 Cellular mechanisms of heart
failure - Cell membrane isolation and reconstitution (dogs,
lambs)
* POlHL-22619-01 0002 Cellular mechanisms of heart
failure - Structure of sodium, potassium-adenosine
triphosphatase (lambs, dogs)
(contd)
'Excludes routine methodokigy OR cavers only general projects which preclude indexing at the specific level.
**OTiented significanthr to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
POIHL 2261901 0005 Cellulai mechanisms ol heart
lailura Molaculac mechanism ol regulation ol caidiac
muscle contiaclion (cattle)
POIHL 22619 01 0008 Cellular mechanisms ol heart
lailure Molecular mechanisms and ditlerential contractile
responsiveness in VSM (dogs)
POIHL 22633 01 Cellular and molecular biology ol
lipoprotein metabolism
POlHL-22633 01 0004 Cellular and moleculai biology ot
lipoprotein metabolism Lipid lipid and lipid protein
interactions in serum lipoproteins (human, rats)
ROIHL 22664-01 Regulation ot myocardial cell growth
(rats, guinea pigs)
ROIHL 2301001 Control and mechanism of platelet
aggregation (human)
R13HL 2307201 Gordon Research Conference-Cardiac and
skeletal muscle (New Hampshire)
ROIHL 2310801 Membrane biochemistry of RH antigens
(human)
' ROlHL-23 11501 Regulation ot active sodium transport
(frogs, rats)
ROlHL-23183 01 Voltage dependent conductance in
membranes
tOLECUlAR BIOIOGY STUDY SECTION
* ROlHL-02063-23 Biochemistry and function ol lipids and
cell membranes (human, yeast, animals)
* ROlHL-0912514 Ultrastrudural cytochemistry (human,
chick)
* R01HL1383108 Factors regulating embryonic cardiac
morphogenesis (chick, salamandra)
* ROlHL-1663704 Development and regression of cardiac
hypertrophy (rats)
* R01HL16730 03 Physiology of mucociliary transport (rats.
frogs, rabbits)
'* ROIHL- 1708005 Localization of pore systems in capillary
walls (rats, mice, rabbits)
'* ROlHL-17525-03 Molecular basis of collagen-platelet
Interaction (human, rat)
•• ROlHL-17551-04 Biosynthesis and metabolism of
procollagen (human, monkeys, mice)
** R01HL17879-04 Molecular structure of the ouabain
sensitive ATPase (dogs)
** ROlHL-19068-03 Changes in membrane properties during
erythropoiesis (chick embryo)
** ROlHL-20300-02 Histone H5 and avian erythropoiesis
(chickens, rabbits)
** ROlHL-22174-01 Assembly of membranes in heart and
yeast mitochondria
** ROlHL-22550-02 Genetic cardiomyopathies in salamanders
and hamsters
** R23HL-22839-01 Cellular translation of liposomally-
delivered mRNA (human, mammals)
MOLECULAR CONDENSATIONS
POIHL- 15486-06 0001 Studies on thrombosis - Studies on
chemistry of fibrinogen (human, dogs)
** P60HL- 16008-06 0017 Wayne State University
comprehensive sickle cell center - Oxygen transport kinetics
of pre- and post-sickling cells (human)
ROlHL-21617-02 Biochemistry of lung proteoglycans
(rabbits, cattle)
" ROlHL-21622-02 Structure and interactions of lung
proteoglycans (cattle)
ROlHL-21645-02 Biosynthesis of fractionated
proteoglycans of lung (rabbits)
MOLECULAR CONDENSATIONS, COPOLYMERS
M POlHL-15195-04 Program project in biological materials
POlHL-15195-04 0001 Program project in biological
materials - Design and synthesis
POlHL-15195-04 0002 Program project in biological
materials ■ Structural and surface characterization
POlHL-15195-04 0003 Program project in biological
materials - Mechanical evaluation and fabrication
POlHL-15195-04 0004 Program project in biological
materials ■ Biological evaluation and surface interaction
studies (dogs)
R01HL15293-07 Sickle cell hemoglobin-Interactions and
aggregation (human)
POlHL-18576-03 0003 Thrombosis research program
project - Biocompatible materials
MOLECULAR CONDENSATIONS, DIMERS
POlHL-06285-18 0164 Cardiovascular-respiratory
physiology and biochemistry - CPK MB isoenzyme
concentration to quantify infarct size (human, animals)
ROlHL-15284-06 Hemoglobin and myoglobin kinetic
studies (human, animals)
P60HL-17269-04 0014 National heart and blood vessel
research and demonstration center - Physio-chemical nature
of lipid deposits in arterial wall (human)
MOLECULAR CONDENSATIONS, MONOMERS
P60HL-17269-04 0014 National heart and blood vessel
research and demonstration center - Physio-chemical nature
of lipid deposits in arterial wall (human)
ROlHL-21 194-02 Development of antithrombogenic plastic
biomaterials
NOlHV-32913-11 Study electrodeless glow discharge for
modifying polymer surface
351
MOLECULAR CONDENSATIONS,
POLYMERIZATION-DEPOLYMERIZATION
•• R01H101562 25 [guilibna in the libiinogen fibrin
conversion (human, cattle)
POIHL 031 74 23 0002 Mechanisms of acute vascular
reaction to in|ury Chemical structure, pathological
significance of amyloid substance (human, mice)
ROIHL 05791 18 Structure and function in hemoglobins
(human)
P01HL06350 17 0020 Hemostasis research program
project Structure and function of coagulant venom
proteases
R01HL07379 13 Structure and function of fibrinogen
(human)
ROIHL 10383 12 Physical-chemical studies of hemoglobins
and erythrocyte (human)
POIHL 11310 12 0103 Mechanisms of cardiovascular
disease Heparin- Metabolism and function
•* ROIHL 12256 15 Polymerization of sickle-cell hemoglobin
(human)
ROIHL 13164 07 Interaction of the alpha and beta chains
of human hemoglobin
ROIHL 13870-09 Control of myocardial sarcotubular
calcium stores (dogs)
P60HL15157-07 0018 Comprehensive center for sickle
cell disease Red blood cell membrane physiology in sickle
cell anemia (human)
** P60HL 15168-07 0009 Comprehensive sickle cell disease
center Spin label study of sickling (human)
*• POIHL 15195-04 0001 Program project in biological
materials Design and synthesis
•• ROlHL-15226-06 Interaction of blood cells with fibrinogen
and fibrin (human, animals)
ROIHL 15293-07 Sickle cell hemoglobin -Interactions and
aggregation (human)
POlHL-16833-04 0001 Hemoglobin and red cell system in
hemoglobinopathies Motility, association and ligand
binding in hemoglobin-Hydrogen exchange
** POlHL-16833-04 0002 Hemoglobin and red cell system in
hemoglobinopathies - Polymerization and gel formation in
solutions of hemoglobin A and S (human)
POlHL-16833-04 0017 Hemoglobin and red cell system in
hemoglobinopathies • Sulfhydryl group blockade antisickling
effect (human)
** ROIHL 16927-05 Structure and function of normal and
abnormal hemoglobin (human)
R01HL17411-04 Molecular studies of red blood cell
spectrin (human)
POlHL-17419-04 0001 Studies on mechanisms of
hemostasis Structure and metabolism of fibrinogen
(human)
** ROlHL-17552-03 Sickling inhibition by chemical
modification of hemoglobin (human)
ROlHL-17828-04 Kinetic studies of hemeiythnn reactions
(marine worms)
** R01HL-18030-04 The role of contractile proteins in
platelets (human, rabbits)
ROlHL-18533-03 Microcrystalline and crystalline fibrinogen
(cattle, bacteria)
ROlHL-18672-03 Dynamic studies of clot structure
formation (human)
ROlHL-18818-04 Stereochemical mechanism of sickling ot
hemoglobin S (human)
ROlHL-19323-03 Studies of platelet microtubule protein
ROlHL-19419-03 Cellular interactions with foreign
materials (mammals)
ROlHL-19456-03 Immunoglobulins associated with serum
hyperviscosity (human)
ROlHL-20106-02 Coupling of platelet contractile proteins
to fibrin (human)
ROlHL-20902-02 Studies on marginal band system of
erythrocytes (amphibians, reptiles, fish)
** P60HL-20985-01 0003 Northern California sickle cell
center - Kinetics of sickling and clinical manifestations in
sickling disorders (human)
POlHL-21015-02 0002 Sickle cell anemia and other
hemoglobinopathies - Molecular events proceeding gelation
of Hb S
POlHL-2 10 16-02 0003 Sickle cell anemia and other
hemoglobinopathies - Role of non-S hemoglobin in gelation
and sickling
POlHL-21016-02 0004 Sickle cell anemia and other
hemoglobinopathies - Kinetics of sickling
POlHL-21016-02 0005 Sickle cell anemia and other
hemoglobinopathies - Ligand kinetics in normal and Hb S
containing erythrocytes (human)
POlHL-21016-02 0006 Sickle cell anemia and other
hemoglobinopathies - Analysis of the oxygen dissociation
curve of Hb S-containing red cells
POlHL-21016-02 0007 Sickle cell anemia and other
hemoglobinopathies - Cellular determinants of red cell
sickling
POlHL-21016-02 0008 Sickle cell anemia and other
hemoglobinopathies - The clinical variations of sickle cell
anemia
POlHL-21016-02 0009 Sickle cell anemia and other
hemoglobinopathies - Nitrogen mustards and their potential
use as antisickling agent
POlHL-210 16-02 0010 Sickle cell anemia and other
hemoglobinopathies - Alkylureas as potential antisickling
agents
MOL
ROIHL 22505 01 Molecular pathology of fibrinogen and
factor XIII (human, animals)
ROIHL 23267 01 Rheology and kinetics ol hemoglobin S
gelation (human)
NOIHV 32913 1 1 Study electrodeless gtow discharge lor
modifying polymer surface
MOLECULAR CONDENSATIONS, POLYMERS
(GENERAL)
SEE ALSO MOLECULAR CONDENSATIONS. RESINS
SEE ALSO MOLECULAR FILMS
SEE ALSO PUSTICS
•• P01HL06285 18 0215 Cardiovascular respiratory
physiology and biochemistry Conformation of biopolymers
POIHL 11310 12 0103 Mechanisms of cardiovascular
disease Heparin Metabolism and function
ROl HL 1 14 18 09 poly diaminophosphazenes
POlHL-13738-08 0004 Cardiac assist devices and
artificial hearts Hematological evaluation ot prosthetic
materials (calves)
POIHL 1373808 0005 Cardiac assist devices and
artificial hearts Development of new materials for
artificial heart and assist devices (sheep, dog)
ROlHL-15155-05 Rheology of pulmonary secretions (dogs)
** POIHL 15195-04 0003 Program pro)ect in biological
materials Mechanical evaluation and fabrication
•* R01HL1552006 Total blood replacement by fluorocarbons
and polyols (rats)
ROIHL 18764-03 Biosorbable thromboresistant surfaces
(dogs. rats, swine, human)
ROIHL 19173-03 Analysis of blood trauma from
microporous oxygenators (human, dogs, rabbits)
" ROIHL 19419-03 Cellular interactions with foreign
materials (mammals)
R01HL-20073-02 Blood compatible materials by fluid
perfusion (human, dogs)
** ROlHL-20251-02 A novel approach to nonthrombogenic
polymer surfaces (sheep, cattle)
" ROlHL-20313-02 Surface-induced thrombosis-Modification
of albumin variants (human, goat)
** ROlHL-21001-01 Protein and thrombus deposition on
vascular grafts
POlHL-21016-02 0001 Sickle cell anemia and other
hemoglobinopathies • Supramolecular models of Hb S-
Mutational and EM approach
ROlHL-21194-02 Development of antithrombogenic plastic
biomaterials
ROlHL-21329-02 Beta-receptor regulation and cardiac
sites of drug action (cat, guinea pig. rat)
** ROlHL-21769-01 Blood compatible benzamidine containing
polymers
R23HL-21805-01 Tissue cell interactions with vascular
prostheses (human, rats, mice)
M POlHL-22163-01 Surface thrombogenesis-Mechanisms and
prevention
** POlHL-22163-01 0001 Surface thrombogenesis-
Mechanisms and prevention Initial blood protein and
platelet interactions with biomaterials (baboons)
** POlHL-22163-01 0002 Surface thrombogenesis-
Mechanisms and prevention - Laser-scattering detection of
microemboli in blood flow (baboons)
** POlHL-22163-01 0003 Surface thrombogenesis-
Mechanisms and prevention - In vivo mechanisms of
biomaterial thrombogenesis and its prevention (baboons)
** POlHL-22163-01 9001 Surface thrombogenesis-
Mechanisms and prevention - Polymers for studing blood-
material interactions core
POlHL-22602-01 0003 Pathophysiology of the
endothelium - Mechanisms of endothelial proliferation
(human, animals)
ROlHL-23120-01 Chelating agents as blood substitutes
•* NOlHV-12017-15 Fabrication of grafted hydrogel coatings
for plastic heart assist devices
NOlHV-12065-16 Fabrication of implantable artificial heart
devices (animals)
** NOIHV 32913-U Study electrodeless glow discharge for
modifying polymer surface
** N01HV-42984-05 Interactions of modified biopolymers with
blood (humans, rats)
** NOlHV-72918-01 Test polymers for circulatory assist
devices
** NOlHV-72919-01 Test polymers for circulatory assist
divices
MOLECULAR CONDENSATIONS, RESINS
SEE ALSO PLASTICS
" POlHL-15596-05 0020 Coagulation, fibrinolysis,
hemostasis and hepatitis - Affinity chromatography
MOLECULAR CYTOLOGY STUDY SECTION
** ROlHL-19132-04 Role of zinc transferrin in lymphocyte
transformation (human)
** ROlHL-21096-02 Sickle cell crisis-Role of the erythrocyte
membrane (human)
** R23HL-21189-01 Regulation of pulmonary endothelial cell
activities (human, cattle)
" ROlHL-21217-01 Ion and 5-hydroxytryptamine transport by
platelets
** ROlHL-21845-01 Human red cell membrane-Structure and
function
** ROlHL-21970-01 Myofibrillar assembly and breakdown in
cardiac muscle (rats)
(contd)
•Excludes routine methodology OR covers only general projects which preclude
••Oriented significantly to above subject
indexing at the specific level.
t* Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
MOL
** ROlHL-22367-01 Estrogen receptors in verv low density
lipoproteins (chicken livers)
** ROlHL-23593-01 Mast cell granules-Structure and
secretion (rats)
MOLECULAR FILMS
SEE ALSO MOLECUUR CONDENSATIONS. POLYMERS
(GENERAL)
POlHL-15195-04 0002 Program project in biological
materials ■ Structural and surface characterization
POlHL-15195-04 0003 Program project in biological
materials - Mechanical evaluation and fabrication
** NOlHV-42928-07 Continued development of carbon film
deposits for prosthetics
MOLECULAR FILMS, MONOMOLECULAR FILMS
POlHL-06285-18 0213 Cardiovascular-respiratory
physiology and biochemistry - Membrane structure and
function-Gas vacuole membrane (Halobacterium)
P50HL-1414708 0003 Specialized center of research in
thrombosis - Surface thrombogenicity and phospholipid
vesicle physical properties
P50HL-1414708 0014 Specialized center of research in
thrombosis - Theoretical models for electrostatic effects in
blood clot formation
P50HL 14147-08 0015 Specialized center of research in
thrombosis ■ Charge related properties of phospholipid
surfaces in monolayers and vesicles
P50HL-15062-07 0007 Study of lipoproteins, artery wall.
and atherosclerosis - Physical chemistry of lipid-protein
interaction (human)
P50HL-15062-07 0008
and atherosclerosis
monkey)
P01HL16607-05 0001
Study of lipoproteins, artery wall
Lipid modifying enzymes (human.
Calcium ion and control of
cardiovascular function - Bilayer lipid membranes,
antibiotic probes, and SR function
MOLECULAR FRICTIONAL PROPERTIES
SEE ALSO PHYSICAL PROPERTIES. VISCOSITY-
VISCOEUSTICITY
ROlHL-18004-02 Transport through arterial wall-
Biophysical aspects (rabbits)
MOLECULAR INTERACTIONS NONBONDING
ROlHL-10383-12 Physical-chemical studies of hemoglobins
and erythrocyte (human)
ROlHL-13909-27 Physiochemistry and immunology of
macromolecules
P50HL-14147-08 0014 Specialized center of research in
thrombosis • Theoretical models for electrostatic effects in
blood clot formation
P50HL-1506207 0001 Study of lipoproteins, artery wall.
and atherosclerosis - Structure and molecular interactions
of serum lipoproteins (human, monkey)
POlHL-15195-04 0002 Program project in biological
materials - Structural and surface characterization
ROlHL-21791-01 Precipitation of proteins with poly
(ethylene glycol) (human)
MOLECULAR LEVEL STUDIES OF NEOPLASMS
SEE NEOPLASMS CHARACTERISTICS, MOLECUUR LEVEL
STUDIES
MOLECULAR MONOLAYERS
SEE MOLECULAR FILMS, MONOMOLECULAR FILMS
MOLECULAR ORBITALS
SEE ELECTRONIC SPECTRA, MOLECULAR ORBITALS
MOLECULAR POLARITY
ROlHL-16101-05 Protein-lipid interaction (bacteria,
models)
ROlHL-21096-02 Sickle cell crisis-Role of the erythrocyte
membrane (human)
MOLECULAR REARRANGEMENT
ROlHL-05556-19 Proteins, lipoproteins -Structure and
reactivity (chicken, human, diving mammals)
ROlHL-09544-12 Biochemistry of contractile proteins
(animals)
ROlHL-10383-12 Physical-chemical studies of hemoglobins
and erythrocyte (human)
ROlHL-1252410 Reaction of hemoglobin with ligands and
antibodies (human, carp)
R01HL12526-09 Raman spectra of heme proteins and
related molecules
** ROlHL-12528-10 NMR relaxation of liquid crystal systems
ROlHL-13035-08 Heart mitochondrial malate
dehydrogenase regulation
ROlHL-13164-07 Interaction of the alpha and beta chains
of human hemoglobin
ROlHL-14508-10 Structure and function of respiratory
hemoproteins
R01HL14680-07 Specific enrichment of myoglobins for
carbon 13 NMR (catacea)
R01HL15284-06 Hemoglobin and myoglobin kinetic
studies (human, animals)
ROlHL-15391-07 EPR studies on rotational motion of
myosin and actin
ROlHL-1 5460-06 Molecular adaptation-Hemoglobin
systems of fish (marine)
R01HL17494-07 Mechanism of liqand binding to
hemoglobin (human)
352
ROlHL-17552-03 Sickling inhibition by chemical
modification of hemoglobin (human)
ROlHL-17878-04 Structural studies of the human
erythrocyte membrane
ROlHL-18226-04 Mechanism of oxygen supply to tissue
(human, animals)
ROlHL-18304-03 FT-infrared spectroscopy of heart muscle
energetics (cattle)
R01HL18309-04 Oxygen transport -Hemoglobins with
modified hemes (horse)
ROlHL-18533-03 Microcrystalline and crystalline fibrinogen
(cattle, bacteria)
R01HL19481-03 High-field NMR studies of respiratory
proteins (human, horse, fish, microbes)
ROlHL-19982-02 Blood coagulation-Proteinmetal ion-lipid
interactions
ROlHL-20464-01 Regulation of cardiac and skeletal
muscle contraction (mammals)
ROlHL-2246101 Cardiac tropomyosin and tropomyosin-
action interactions (rabbit)
ROlHL-22729-01 Intracellular degradation of newly
synthesized collagen (human, chick, rabbit)
MOLECULAR SHAPE
SEE CHEMICAL STRUCTURE, MOLECULAR SHAPE
MOLECULAR SIEVES
SEE PHYSICAL SEPARATION, MOLECULAR SIEVES*
MOLECULAR SIZE
SEE ALSO CHEMICAL STRUCTURE, CHAIN LENGTH
SEE ALSO MOLECULAR WEIGHT
SEE ALSO MOLECULES, MACROMOLECULES
POlHL-16851-04 0008 Human red cell membrane in
health and disease • Force balance in red cell interactions
(human)
ROlHL-18004-02 Transport through arterial wall-
Biophysical aspects (rabbits)
ROlHL-19095-03 Laser spectroscopy of lipoproteins
(human)
R01HL1949103 Mechanism of iron storage and
mobilization by ferritin (horse)
ROlHL-21622-02 Structure and interactions of lung
proteoglycans (cattle)
ROlHL-21877-01 Iso-renins in the hypertensive rat
" POlHL-22602-01 0002 Pathophysiology of the
endothelium - Molecular charge and endothelial
permeability (rats, mice)
MOLECULAR STABILITY
SEE CHEMICAL STABILITY
MOLECULAR STRUCTURE
SEE CHEMICAL STRUCTURE
MOLECULAR STRUCTURE-BIOLOGICAL ACTIVITY
SEE CHEMICAL STRUCTURE-BIOLOGICAL ACTIVITY
MOLECULAR VIBRATIONS
SEE CHEMICAL BONDS, VIBRATIONS
MOLECULAR WEIGHT
SEE ALSO MOLECULAR SIZE
POlHL-031 74-23 0002 Mechanisms of acute vascular
reaction to injury ■ Chemical structure, pathological
significance of amyloid substance (human, mice)
POlHL-09011-15 0019 A research and resource program
in blood • The transport mechanism of mRNA (rat, yeast,
ascites cells)
ROlHL-12256-15 Polymerization of sickle-cell hemoglobin
(human)
ROlHL-13164-07 Interaction of the alpha and beta chains
of human hemoglobin
ROlHL-14938-06 Contractile proteins of heart muscle
(dogs, rabbits)
P01HL15596-05 0007 Coagulation, fibrinolysis.
hemostasis and hepatitis - Structural studies and
fractionation of urokinase (human)
** POlHL-15596-05 0008 Coagulation, fibrinolysis,
hemostasis and hepatitis - Structural studies and
fractionation of antihemophilic factor (human)
POlHL-15835-06 0004 Study of muscles related to heart
disease - Actomyosin systems and cell motility (slime
molds, human)
POlHL-1613705 0001 Alveolar biology - Chemical
characterization of surfactant system-Lipid and lipid
protein fractions
POlHL-16387-04 0008 The blood vessel and
thrombogenesis - Factor VIII in hemostasis (human,
rabbits)
ROlHL-17364-04 'Big renin'-Biochemical and clinical
studies (human)
R01HL17402-04 Mechanism of contact activation of
intrinsic clotting (human)
R01HL18028-03 Absorption of nonvolatile compounds
from the lung
ROlHL-1806802 Chemistry and activity of homologous
heparin fractions (rodents)
POlHL-18577-03 0004 Lipoproteins-Cell surface
interactions - Analysis and chemical modification of
proteins in lipid transport (human, dogs)
ROlHL-186 18-04 Purification and function of human HMW
kininogen
ROlHL-18746-02 Chemical studies on proteolipid
apoproteins (cattle)
MON
POlHL-18974-03 0009
hypertension program
hydroxylase (rats)
POlHL-18974-03 0011
hypertension program
Experimental neurogenic
Biochemistry of brain tyrosine
Tracheal mucin synthesis In experimental
Biochemistry of lung proteoglycans
Experimental neurogenic
Biochemistry and regulation of
brain tryptophane hydroxylase (rats)
P50HL-19190-02 0005 Pulmonary SCOR-Pathophysiology,
management of IRDS ■ Glycoproteins in mucous secretions
(human, cattle)
R01HL19331-03 Hirudin isolation and utilization (leeches)
ROlHL-20500-02 Diabetic human brain microvascular
basement membrane (human)
ROlHL-20547-02 Glycoproteins in pulmonary alveolar
proteinosis (human)
ROlHL-2109602 Sickle cell crisis -Role of the erythrocyte
membrane (human)
R23HL-21369-02
bronchitis (rats)
ROlHL-21617-02
(rabbits, cattle)
ROlHL-21622-02 Structure and interactions of lung
proteoglycans (cattle)
ROlHL-2164102 Structural studies of lung proteoglycans
(pigs, cattle, rabbits)
ROlHL-21686-02 Purification of erythropoietin (human)
ROlHL-21701-02 Purification of erythropoietin (human)
ROlHL-21791-01 Precipitation of proteins with poly
(ethylene glycol) (human)
ROlHL-22288-01 Renin and precursors-Structure and
function (mice)
ROlHL-22875-01 Crotalase-Chemistry. physiology, clinical
potential (rats, rabbits)
ROlHL-23200-01 Isolation of CA binding proteins from
erythrocytes (human)
NOlHR-72920-01 Identify and quantify cystic fibrosis
factors (human)
NOlHR-72923-01 Cystic fibrosis factor identification and
quantification (human)
MOLECULES, MACROMOLECULES
SEE ALSO MOLECULAR CONDENSATIONS. POLYMERS
(GENERAL)
** POlHL-06285-18 0214 Cardiovascular-respiratory
physiology and biochemistry - Membrane structure and
function-EM of macromolecules
POlHL-06370-17 0004 Cardiopulmonary and renal
pathology research center - Lymphocytes in graft rejection
and immune surveillance (human)
POlHL-08805-15 0025 Regulation of ventilation and
pulmonary circulation - Pulmonary edema (rabbits)
POlHL-0880515 0048 Regulation of ventilation and
pulmonary circulation - Permeability of alveolo-Capillary
membrane in normal pulmonary hypertensive lung
** POlHL-11310-12 0098 Mechanisms of cardiovascular
disease - Protein chemistry of thy-1 and related
synaptosomal proteins (mice)
ROlHL-15270-06 Local mechanical properties of the aortic
tissue (dogs, pigs)
** ROlHL-15793-06 Molecular aspects of erythrocyte
membrane resealing (human)
POlHL-16137-05 0008 Alveolar biology - Macromolecular
events in pulmonary cells in toxic environments (animals)
POlHL-16607-05 0007 Calcium ion and control of
cardiovascular function - Ultrastructure and conformation
in sarcoplasmic reticulum (rabbits)
R01HL16666-05 Micropinocytosis in isolated capillary
endothelium
•* ROlHL-18010-04 Capillary transport of large molecules
(dogs, sheep)
POlHL-18827-02 0002 Platelet vessel wall interactions in
thrombogenesis - Interactions of vessel wall
macromolecules with factor XII (human, rats)
P50HL19157-02 0004 Studies in cystic fibrosis and
bronchiolitis - Macromolecular regulators of mucus
secretion-Invertebrate model
ROlHL-19454-02 Rheological factors in transport across
arterial wall (dogs)
R23HL-19594-01 Tropocollagen and tropoelastin uptake in
lung cells (human)
ROlHL-21188-02 Pulsatory water flux and endothelial cell
desquamation
ROlHL-21329-02 Beta-receptor regulation and cardiac
sites of drug action (cat, guinea pig. rat)
ROlHL-21438-02 Structure and permeability of arterial
endothelium (pigs)
ROlHL-22463-02 Pinocytotic vesicles and pulmonary
edema (rats)
POlHL-22602-01 0003 Pathophysiology of the
endothelium - Mechanisms of endothelial proliferation
(human, animals)
ROlHL-22883-01
ROlHL-22924-01
Pharmacology of molluscan hearts (also
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
••Oriented significantly to above subject.
Lung epithelial cell interactions in vitro
The airway mucosal barrier (guinea pigs)
MOLLUSKS*
ROlHL-09283-14
rabbits)
MOLLUSKS, GASTROPODS*
** ROlHL-22201-01 Pharmacology and chemistry of
nudibranch toxins (guinea pigs. rats, mice)
MONITORING DEVICES
SEE BIOMEDICAL SYSTEMS AUTOMATED. MONITORING
DEVICES
(contd)
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
N
NITORINO DEVICES (ENVIRONMENTAl)
Stt AIR SAMPUNG MONIUIRmC,
NITORINO DEVICES K3R PATIENT
AONITORINO
Stt BIOMEDICAL SYSTEMS AUTOMATED, PATIENT
MONITORING (MONITORING DEVICES)
INITORING OF PATIENTS (AUTOMATED)
SEE BIOMEDICAL SYSTEMS AUTOMATED. PATIENT
MONITORING (MONITORING DEVICES)
INOAMINE OXIDASE
SEE OXIDOREDUCTASES, AMINE OXIDASE (fUVIN
CONTAINING)
SEE OXIDOREDUCTASES. MONOAMINE OXIDASE
>NOAMINE OXIDASE INHIBITORS
SEE ENZYME INHIBITORS, MONOAMINE OXIDASE INHIBITORS
JNOCROTALINE
SEE ALKALOIDS. MONOCROTALINE
3NOCYTES
SEE BLOOD CELLS. MONOCYTES
3NOMERS
SEE MOLECULAR CONDENSATIONS. MONOMERS
3NOMOLECULAR FILMS
SEE MOLECULAR FILMS. MONOMOLECULAR FILMS
ONOPHENOL MONOOXYGENASE
SEE OXYGENASES. MONOPHENOL MONOOXYGENASE
ONOPHENOL OXIDASE
SEE OXYGENASES, MONOPHENOL MONOOXYGENASE
ONOSACCHARIDES
SEE CARBOHYDRATES. MONOSACCHARIDES
ORBIDITY STATISTICS
SEE POPULATION STUDIES HUMAN, MORBIDITY
ORPHINES
SEE ALKALOIDS, MORPHINES
lORPHOGENESIS
SEE GROWTH AND DEVELOPMENT, HISTOGENESIS
lORTALITY STATISTICS
SEE POPUUTION STUDIES HUMAN, MORTALITY
(OSAICISM
SEE TISSUE MOSAICISM
tOSQUITOES
SEE ARTHROPODS, INSECTS, DIPTERA. CULICIDS.
MOSQUITOES*
BOSSES
SEE PLANTS, BRYOPHYTES, MOSSES*
AOTION
SEE ENVIRONMENT, GRAVITY-MOTION
AOTION IMAGES, SCANNING
SEE RADIOGRAPHY, SCANNING, DSR
MOTION PICTURES
SEE OPTICS, PHOTOGRAPHY, CINEMATOGRAPHY*
MOTIVATION
SEE PSYCHOLOGY, MOTIVATION
MOTOR CORTEX
SEE BRAIN. CEREBRAL CORTEX, MOTOR CORTEX
MOTOR IMPULSES
SEE PSYCHOMOTOR FUNCTION
MOTOR NEURONS
SEE NEUROMOTOR SYSTEM, MOTOR NEURONS
MOUSE LEUKEMIA VIRUS (GENERAL)
SEE VIRUSES, ONCORNA, LEUKEMIA MOUSE
MOUSE LEUKEMIA VIRUS, RAUSCHER
SEE VIRUSES, ONCORNA, LEUKEMIA MOUSE RAUSCHER
MOVEMENT DISORDERS
SEE NEUROMOTOR DISORDERS
MOVEMENT PERCEPTION, BODY
SEE SENSORY-PERCEPTUAL PROCESSES, PROPRIOCEPTION
MRL-41
SEE STILBENES, CLOMIPHENE
MRNA
SEE NUCLEIC ACIDS, MRNA
MT DNA
SEE NUCLEIC ACIDS, MT DNA
MUCIN
SEE PROTEOGLYCANS, MUCIN
MUCINASE
SEE CARBOHYDRASES, HYALURONIDASE
MUCINASE (HYAIURONATE LYASE)
SLf POlYSACCHARIDf CO lYASfS, HYIURONAIE LYASE
MUCOIDS
Sff PROIFOGIYCANS
MUCOLIPIDOSIS II
SEE METABOLIC DISORDERS INBORN.
MUCOPOLYSACCHARIDOSIS, ICELL DISEASE
MUCOLYTIC AGENTS
SEE RESPIRATORY DRUGS, EXPECTORANTS AND MUCOLYTICS
MUCOPOLYSACCHARIDES
SEE POLYSACCHARIDES, GLYCOSAMINOGLYCANS
MUCOPROTEINS
SEE PROTEOGLYCANS
MUCOSA, INTESTINAL
SEE GASTROINTESTINAL SYSTEM. INTESTINES, MUCOSA
MUCOUS MEMBRANE
SEE MEMBRANE, MUCOUS MEMBRANE
MUCOVISCIDOSIS
SEE METABOLIC DISORDERS INBORN, CYSTIC FIBROSIS
MUCUS
SEE BODY FLUIDS, MUCUS
MULTILAYER MEMBRANES
SEE MEMBRANE. MULTILAYER MEMBRANES
MULTIPLE DRUG THERAPY
SEE DRUGS. CHEMOTHERAPY. DRUGS COMBINATION
MULTIPLE MYELOMA
SEE NEOPLASMS OF BLOOD AND RE SYSTEM. BONE MARROW
NEOPLASMS. MULTIPLE MYELOMA
MULTIPLE RADIOTRACER
SEE RADIOTRACERS. DOUBLE (MULTIPLE)*
MULTIPLE SCLEROSIS
SEE NERVOUS DISORDERS. MYELINOPATHIES, MULTIPLE
SCLEROSIS
MULTIPLE TREATMENT WITH DRUGS
SEE DOSAGE AND ROUTE, RATE AND DURATION OF
ADMINISTRATION
MUNICIPAL HEALTH PLANNING
SEE HEALTH CARE (SERVICES)(RESOURCES)PLANNING,
REGIONAL MEDICAL PLANNING
MURAMIDASE
SEE CARBOHYDRASES, LYSOZYME \
MUSCARINIC AGENTS
SEE NEUROPHARMACOLOGICAL AGENTS,
PARASYMPATHOMIMETIC
MUSCARINIC RECEPTORS
SEE NEUROTRANSMITTER RECEPTORS, CHOLINERGIC
RECEPTORS
MUSCLE CELLS
POlHL-06285-18 0179 Cardiovascularrespiratoty
physiology and biochemistry ■ Regulation of myocardial cell
growth (rats, chick embryo)
P01HL-063 14-17 0066 Immunologic mechanisms in
cardiovascular disease Sensitization, cell-mediated
cytotoxicity, role of lymphocytes (human, mice)
ROlHL-10503-13 Cardiac ion transport and ultrastructure
(rats, guinea pigs, rabbits)
P50HL-14164-07 0035 A/S SCOR-Comparative and
experimental atherosclerosis - Lipid metabolism-Interaction
with arterial metabolism (monkey, pigeon)
P50HL-14 164-07 0036 A/S SCOR -Comparative and
experimental atherosclerosis Connective tissue
metabolism -Interaction with arterial metabolism (monkeys)
P50HL-14230-07 0095 A/S SCOR -Lipids, atherosclerosis
and thrombosis Blood platelet adherence to endothelial
smooth muscle cells, fibroblast (human)
P50HL14230-07 9002 A/S SCOR -Lipids, atherosclerosis
and thrombosis ■ Core tissue culture laboratory
POlHL-14388-07 0178 Regulation of the circulation in
pathological states - Structural and functional
consequences of denervation (rats)
** POlHL-14388-07 0179 Regulation of the circulation in
pathological states - Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
ROlHL-14523-07 Generation and regulation of force in
smooth muscle (animals)
P50HL-15062-07 0012 Study of lipoproteins, artery wall,
and atherosclerosis - Lipoprotein stimulation of arterial
smooth muscle cell proliferation (mammals)
P50HL-15062-07 0019 Study of lipoproteins, artery wall,
and atherosclerosis - Factors regulating lipoprotein-smooth
muscle cell interaction (monkey)
R01HL-15646-03 Lipid studies in vascular smooth muscle
cells (human, monkeys)
POlHL-15832-06 9001 Chemical-structural predispositions
to lung injury - Tissue culture studies of lung cell function-
-Core facility
MUS
PO I HI 15834 06 0071 Study ol muul«» reljled to heart
disease Fast kinetic studies in muscle subcellular
organelles (animals)
' PbOHL 17648 04 0026 Study ol ischemic heart disease
Control ol muscle cell prolileration (organ culture)
PbOHl 17682 04 0023 Study o( ischemic heart disease
Core cell and organ culture laboratory (mice)
ROIHL 1/998 04 Regulatory mechanisms in blood
circulation (dogs)
' ROIHL 18077 04 Smooth muscle cell organization and
Ca20 concentration control (chickens)
PSOHL 1831803 0015 Pathogenesis and complications of
hypertension Cultured smooth muscle cells and
microvessel metabolism (mammals)
POIHL 18645 03 0004 Biology o( the artery wall and
atherosclerosis Human arterial smooth muscle cell and
lipoprotein interaction
ROIHL 19299 03 Myoglobin and oxygen supply to heart
and muscle cells (rats, pigeons)
ROIHL 1932503 Phosphodiesterase inhibition and muscle
contraction
* POIHL 20592 02 0013 Cell biology of cardiac and
skeletal muscle Sarcoplasmic reticulum in skinned
muscle cells (frogs)
ROIHL 20783 02 Airway reactivity Badrenoceptors and
prostaglandins (guinea pigs)
POlHL-20948 02 0002 Molecular basis of cholesterol
metabolism LDL pathway in cell lines with informative
properties other than fibroblasts
P01HL20948-02 9001 Molecular basis of cholesterol
metabolism - Tissue culture core laboratory
•* POIHL 2098402 0004 Cellular mechanisms in cardiac
hypertrophy - Myofibril accumulation in cardiac and
vascular muscle cells in hypertrophy
** P50HL-21006-02 0004 Specialized center of research in
arteriosclerosis - Regulation of growth of human arterial
smooth muscle cells by platelets
ROlHL-21 136-02 Ion activities and transport in cardiac
muscle cells (sheep)
R01HL2119502 Innervation of the heart- Acetylcholine
receptors (frogs)
R23HL-21539-02 Mechanical properties ol isolated small
bronchioles (rabbits)
ROlHL-21670-01 Antiarrhythmic studies on 2substituted
aminoindenes (dogs)
ROlHL-22264-01 Regulation of contraction in vascular
smooth muscle (dogs)
POlHL-22602-01 0001 Pathophysiology of the
endothelium - Platelet-endothelial interactions in vitro
(human, cattle)
POlHL-22633-01 0002 Cellular and molecular biology of
lipoprotein metabolism - Sterol metabolism in tissue
culture cells
ROlHL-23161-01 0004 Biology of myocardial ischemia -
Structure of myofibrils and membranes in early ischemia
(dogs, rabbit, rodents)
ROlHL-23210-01 Biology of normal and hypertrophied
pulmonary vessels (cat, human)
ROlHL-23542-01 Pulmonary vascular smooth muscle cell
dynamics (rat, rabbit)
R01HL-23618-01 Substrate metabolism in isolated
myocytes in shock (dogs, rats, guinea pigs)
MUSCLE CELLS, MYOBLASTS
ROlHL-11551-11 RNA and protein synthesis in repair of
heart injury (mice, rats)
MUSCLE CELLS, MYOEPITHELIAL CELLS
P50HL-14138-05 0015 Center for research on
atherosclerosis ■ Arterial wall -Intermediary metabolism,
enzyme activity and bioenergetics
P50HL-14147-08 0012 Specialized center of research in
thrombosis - Tissue culture study of arterial cells (human,
hamster)
ROlHL-20391-03 Polydisperse LDL-Structure, metabolism
and function (human)
MUSCLE CELLS, SARCOMERES
** P01HL11307-12 0003 Biophysical studies in pediatric
cardiology - Cellular biophysics (animals)
POlHL-11351-12 0003 Cellular and molecular
mechanisms of myocardial function - Mechanical and
electrical properties of cardiac muscle (rabbits)
POlHL-12373-10 0001 Cardiopulmonary physiology and
pathophysiology - Mechanics of myocardial contraction
(dogs, rats, swine)
POIHL- 15835-06 0007 Study of muscles related to heart
disease - Structure and function of Limulus striated and
cardiac muscle
POlHL-15835-06 0011 Study of muscles related to heart
disease - Energetics and mechanism of muscle contraction
(frogs, rabbits)
** POlHL-15835-06 0023 Study of muscles related to heart
disease - Cellular basis of the Frank-Starling curve (frogs,
rats)
** ROIHL 16010-16 Cellular basis of cardiac contractility
(frogs)
ROlHL-16606-11 Contraction in heart and other striated
muscles (frogs)
** POlHL-16607-05 0006 Calcium ion and control of
cardiovascular function - Sarcomere and contractile
dynamics of striated muscle cells (animals)
(contd)
"Excludes routine methodology OR covers only general proieds which preclude
**Oriented significanthi to above subject.
indexing at the specific level-
Mi Grant has subproiects describing specific research aspects.
See Appendix for investigators name and grant number.
MUS
R01HL18077-04 Smooth muscle cell organization and
Ca20 concentration contra! (chickens)
** ROlHL-18676-03 Myocardial sarcomere mechanics (rat)
ROlHL-18900-03 Intercellular factors in function of
cardiac cells
R01HL18943-03 Contractile activity of single cardiac cells
ROlHL-19848-02 Contractile activation by rapid
temperature jumps (frogs)
ROlHL-2 1145-02 Response of atria to hyperosmolality-
Mechanisms (rabbits)
R23HL-21167-02 The electrophysiology of cardiac
hypertrophy (rats)
ROlHL-2118202 Active tension and shortening in cardiac
hypertrophy (rabbits)
** ROlHL-21312-01 Sarcomere mechanics in disrupted
ventricular muscle (guinea pigs)
R23HL-21325-02 Sarcomere kinematics in cardiac
contraction (rats, rabbits)
MUSCLE CELLS, SARCOPLASMIC RETICULUM
R01HL-05949-I8 Biochemistry of muscle contraction (rats.
rabbits)
P01HL0630818 0025 Mechanisms and therapy of
circulatory disease - Subcellular calcium pools in the
genesis of arrhythmias (dogs)
POlHL-06312-17 0033 Surgical cardiology - Studies in
cryopreservations (rats)
ROlHL-0923413 Amino acids of contractile proteins of
failing hearts (dogs, hamsters)
ROlHL-09562-14 Cardiac protein synthesis, overload.
alcohol and anoxia (guinea pigs)
ROlHL-10503-13 Cardiac ion transport and ultrastructure
(rats, guinea pigs, rabbits)
ROlHL-10897-12 Effects of hormones on cardiac
electrogenesis (rabbits, guinea pigs, dogs)
POlHL-1 1351-12 0004 Cellular and molecular
mechanisms of myocardial function - Molecular
mechanisms of contractile function and differentiation
(animals)
POlHL-11351-12 0011 Cellular and molecular
mechanisms of myocardial function - Comparative
contractile tissue studies (animals)
ROlHL-12186-09 Calcium transients in striated muscle
and other cells (mammals, frogs)
** ROlHL-12486-10 Structure-function correlation in the
atrium (rabbits)
ROlHL-12997-07 Myocardial defects induced by potassium
depletion (human, rats, cats)
R01HL13619-09 Microsomal electron transport in liver
and heart (human, mammals)
ROlHL-13636-08 Effects of pharmacologic agents on heart
metabolism (human, rodents)
" ROlHL-13870-09 Control of myocardial sarcotubular
calcium stores (dogs)
POlHL-14388-07 0153 Regulation of the circulation in
pathological states - Subcellular distribution of calcium
(rats)
R01HL1471706 Hemodynamics and heart structure-
Ventricular overload (dogs)
ROlHL-15498-06 Effects of physical training on heart
(rats)
ROlHL-15764-05 C-AMP dependent protein kinase in
cardiac contraction (dogs)
ROlHL-15799-04 Effect of anesthetics on myocardial
function (cats)
POIHL- 1583 5-06 0009 Study of muscles related to heart
disease • Aspects of cardiac and skeletal myogenesis
(chick embryo)
POlHL-15835-06 0010 Study of muscles related to heart
disease - Muscle structure and reaction to injury (mice
rats)
POIHL- 1583 5-06 0019 Study of muscles related to heart
disease - Vascular smooth muscle-Electron microscopy,
excitation contraction (animal)
P01HL15835-06 0021 Study of muscles related to heart
disease - Fast kinetic studies in muscle subcellular
organelles (animals)
POlHL-15835-06 0023 Study of muscles related to heart
disease - Cellular basis of the Frank-Starling curve (frogs,
rats)
P01HL15835-06 0027 Study of muscles related to heart
disease - Core ll-lntermediate voltage EM of muscle
ROlHL-1 5888-05 Comparative stereology of the
myocardium (birds, mammals)
R01HL-160I0-16 Cellular basis of cardiac contractility
(frogs)
POlHL-16117-05 0001 Ion movements and membranes in
cardiovascular control Developmental studies of
contractile cell junctions (rats, rabbits, elasmobranch)
POlHL-16117-05 0002 Ion movements and membranes in
cardiovascular control - Fluorescence and excitation-
contraction coupling in heart (frogs)
POlHl-161 17-05 0003 Ion movements and membranes in
cardiovascular control - Fast kinetic study of calcium
membrane interactions
POlHL-iei 17-05 0004
cardiovascular control
Ion movements and membranes in
Optical studies of excitation-
contraction coupling (frogs, snakes)
ROlHL-16152-06 Electrophysiology of neonatal to adult
heart (cats, frogs, guinea pigs)
ROlHL-16233-05 Molecular cardiology of MDP-induced left
ventricular failure (dogs)
354
" P01HL16607-05 0001 Calcium ion and control of
cardiovascular function - Bilayer lipid membranes,
antibiotic probes, and SR function
'* POlHL-16607-05 0003 Calcium ion and control of
cardiovascular function Calcium transport in
sarcoplasmic membranes (animals)
■* POlHL-16607-05 0005 Calcium ion and control of
cardiovascular function - Chemical modifications of the
sarcoplasmic reticulum membranes (rabbits)
■* POlHL-16607-05 0007 Calcium Ion and control of
cardiovascular function - Ultrastructure and conformation
in sarcoplasmic reticulum (rabbits)
ROlHL-16637-04 Development and regression of cardiac
hypertrophy (rats)
ROlHL-16706-04 Excitation-contraction coupling and heart
failure (dogs, rabbits)
P60HL 17269-04 0003 National heart and blood vessel
research and demonstration center - Atherosclerosis -Fatty
acid metabolism in cardiovascular tissue (human, chicken)
P60HL-17269-04 0007 National heart and blood vessel
research and demonstration center - Correlative studies of
experimental myocardial ischemia (dog)
* P60HL-17269-04 0019 National heart and blood vessel
research and demonstration center - Sarcoplasmic
reticulum (dog. rabbit, hamster, cat)
P60HL-17269-04 0021 National heart and blood vessel
research and demonstration center - Gro»»th and
development of heart -Ultrastructure (dog, guinea pig rat
cat)
ROlHL-17592-03 Activation and contraction heat in
enlarged hearts (rabbits)
P50HL-17648-04 0025 Study of ischemic heart disease -
Destruction and repair of cardiac muscle cell constituents
(rat)
P50HL-1 764804 0031 Study of ischemic heart disease -
Ultrastructural consequences of myocardial ischemia (rat)
ROlHL-17702-04 Electro-optical dyes as probes of heart
excitability
ROlHL-18032-03 Development of normal and myopathic
mammalian heart (hamsters)
ROlHL-18070-04 Regulation of intrapulmonary airways
and vessels (human, animals)
ROlHL-18255-04 Lipid-protein interactions and calcium
transport (models)
ROlHL-18280-03 Regulation of cardiac contractility and
metabolism (rats)
ROlHL-18527-03 Subcellular response of heart to
functional overload (hamsters, rats)
ROlHL-18631-03 Ultrastructural correlates of myocardial
ischemia (rats, swine)
* POIHL 18708-03 0004 Oxygen, energy and contractility in
cardiac tissue - Structural-functional studies on
sarcoplasmic reticulum (rabbits)
POlHL-18708-03 0005 Oxygen, energy and contractility in
cardiac tissue - Cytosolic calcium homeostasis and
bioenergetics of cardiac tissue (animals)
ROlHL-19044-03 Effect of drugs on development of
cardiac failure (cats)
ROlHL-19138-03 Contractile activation of skinned cardiac
cells (mammals)
ROlHL-19485-03 Calcium uptake by normal and failed
cardiac ATPase (dogs)
P01HL-I9737-02 0002 Cellular and molecular aspects of
respiratory physiology - Airway smooth muscle in health
and disease (human, animals)
ROlHL-20190-02 Pathogenesis of cardiac hypertrophy
(dogs)
ROlHL-20426-03 Myocardial function in diabetes mellitus
(dog. rat)
■ POlHL-20592-02 0013 Cell biology of cardiac and
skeletal muscle • Sarcoplasmic reticulum in skinned
muscle cells (frogs)
ROlHL-20754-02 Anesthetic-induced myocardial depression
(rabbits)
R01HL-210I4-01 Mechanism of the inotropic action of
cardiac glycosides
ROlHL-21030-01 Calcium regulation and hypertension
(rats)
ROlHL-21145-02 Response of atria to hyperosmolality-
Mechanisms (rabbits)
R0IHL-2137I-02 Energy loss microanalysis of myocardial
cations
ROlHL-21493-02 Contractility in cardiac failure (hamsters)
ROlHL-21670-01 Antiarrhythmic studies on 2-substituted
aminoindenes (dogs)
ROlHL-21812-02 Actions of drugs and ions on cardiac
membranes (rabbits, guinea pigs)
ROlHL-21850-01 Calcium transport in the hypertrophied
myocardium (rats, animals)
ROlHL-22008-01 Left ventrivular calcium content and
contractility (rats)
ROlHL-22039-02 Ion transport in cardiac muscle (dogs.
rodents, cattle)
ROlHL-22135-01 Control of calcium fluxes across cardiac
membranes (dogs, rabbits, guinea pigs)
ROlHL-22137-02 Structure-function pathology of isolated
heart cells (mice, rats)
ROlHL-22361-01 Regulation of cardiac adaptation to
exercise (rats)
POlHL-226 19-01 0003 Cellular mechanisms of heart
failure - Digitalis induced inotropy in myocardial ischemia
heart failure (animals)
MUS
POlHL-22619-01 0008 Cellular mechanisms of heart
failure - Molecular mechanisms and differential contractile
responsiveness in VSM (dogs)
" POlHL-22619-01 0009 Cellular mechanisms of heart
failure - Sarcoplasmic reticulum in cardiac, skeletal and
smooth muscle (rabbits, dogs)
ROlHL-22685-01 Drugs and excitation-contraction coupling
in heart (animals)
ROlHL-22813-01 Palmitylcarnitine Inhibition of ion pumps
in ischemia (dogs)
ROlHL-23128-01 Cardiac contractility-Ischemia and
hypoxia (rabbits, rats)
ROlHL-23142-01 Mechanisms of membrane injury in
myocardial ischemia (dog)
ROlHL-23161-01 0002 Biology of myocardial ischemia -
Palmitylcarnitine inhibition of ion pumps in myocardial
ischemia (dog. sheep)
** ROlHL-23161-01 0003 Biology of myocardial ischemia
Phosphorylase coupling to myocardial sarcoplasmic
reticulum (dog)
ROlHL-23161-01 0004 Biology of myocardial ischemia -
Structure of myofibrils and membranes in early ischemia
(dogs, rabbit, rodents)
ROlHL-23206-01 Repetitive exercise and cardiac
enlargement (dogs)
ROIHL 23210-01 Biology of normal and hypertrophied
pulmonary vessels (cat, human)
ROlHL-23392-01 Membrane binding and transport of
calcium and potassium ionophores
MUSCLE CELLS, SARCOSOMES
P50HL-17648-04 0027 Study of ischemic heart disease -
Phospholipid metabolism following cardiac injury and
repair (rat)
ROlHL-20749-01 Developing heart-Biophysical aspects
(sheep)
MUSCLE CONTRACTION
SEE MUSCLE FUNCTION. MUSCLE CONTRACTION
MUSCLE FUNCTION
ROlHL-05883-18 0003 Reflex control of resistance and
capacitance vessels - Cardiac glycosides and sympathetic
nerve terminals in vascular smooth muscle
POlHL-11351-12 Cellular and molecular mechanisms of
myocardial function
ROlHL-13233-08 Cardiorespiratory control in exercise
(human)
POIHL- 14388-07 0175 Regulation of the circulation In
pathological states - Functional studies of selected proteins
from cardiac muscle
POlHL-15835-06 0012 Study of muscles related to heart
disease - Contraction and energetics of visceral and
vascular smooth muscles (rabbits)
ROlHL-16420-02 Effect of training-detraining on the rat
heart
POlHL-16607-05 0005 Calcium ion and control of
cardiovascular function - Chemical modifications of the
sarcoplasmic reticulum membranes (rabbits)
POlHL-16683-04 Function and growth of cardiac and
skeletal muscle
POlHL-17813-04 0007 Lung disease and the oxygenation
of blood and tissue - Studies on the function of myoglobin
(dogs)
ROlHL-18082-03 Erythrocyte phosphates and vertebrate
gas transport (amphibians, reptiles)
P50HL-19170-02 0009 Harvard pulmonani SCOR-Chronic
diseases of the airways - Ventilatory muscle training in
chronic obstructive pulmonary disease (human)
R23HL-20968-02 Respiratory failure-Control and muscle
dysfunction (human)
ROlHL-22216-02 Vascular mechanisms in renal
hypertension (dogs)
ROlHL-22264-01 Regulation of contraction in vascular
smooth muscle (dogs)
ROlHL-22401-01
the heart
R23HL-22975-01
M
M
blood flow (dogs)
R01HL-230I3-01
(chick embryo)
ROIHL-23239-01
Regulation of tension and active state in
Dynamics of autoregulation of muscle
Smooth muscle development in vitro
Functional characteristics of pulmonary
•Excludes routine methodology OR covers only general projects which preclude indexing
"Oriented significantly to above subject.
at the specific level.
M Grant has subprojeds describing specific research aspects.
See Appendix lor investigator's name and grant number.
vascular smooth muscle (dogs)
MUSCLE FUNCTION, ELECTROMYOGRAPHY*
P01HL-14580-07 0003 Program project in respiratory
mechanics - Chest wall mechanics and respiratory control
(human, dogs)
ROlHL-17314-04 Effects of anesthesia and loading on
respiration (human, cats)
R23HL-20968-02 Respiratory failure- Control and muscle
dysfunction (human)
R23HL-21405-01 Respiratory muscles in regulation of
infant breathing (human)
MUSCLE FUNCTION, MUSCLE CONTRACTION
SEE ALSO CARDIOVASCUUR FUNCTION. VASOMOTION
SEE ALSO GASTROINTESTINAL PRESSURE-MOTILITY
SEE ALSO HEART FUNCTION. HEART CONTRACTION
SEE ALSO NEUROMOTOR SYSTEM. NEUROMUSCULAR
TRANSMISSION
SEE ALSO RESPIRATORY FUNCTION. BRONCHOMOTION
ROlHL-02953-17 Autonomic and cardiovascular
pharmacology (rats, rabbits, dogs, guinea pigs)
(contd)
.^SSES^l
MUS
■• R01HL03290-22 Controls ol cardiac and vasculat smooth
muscles (cats. rats, dogs)
HOIHI 0b883 18 0002 Retlei control ol resistance and
capacitance vessels Adenosine, adenine nucleotides and
vascular smooth muscle (dog)
ROIHL 05883 18 0007 Rellex control ol resistance and
capacitance vessels Prostaglandins and skeletal muscle
blood How (dogs)
•* R01Hl0b949 18 Biochemistry o( muscle contraction (rats.
rabbits)
•* P01H106285 18 0173 Cardiovascular respiratory
physiology and biochemistry Skeletal and cardiac muscle
function
POIHL'06314 17 0053 Immunologic mechanisms in
cardiovascular disease Cellular functions controlled by
cyclic GMP (human, mice, guinea pigs)
ROIHL 08359 14 Morphopharmacology of vascular
adrenergic transmission (rabbits, rats)
M POIHL'08682'15 Regulation of the cardiovascular system
** POlHL-08682 15 0005 Regulation of the cardiovascular
system Smooth muscle and mechanical properties ol
blood vessels (dogs, human)
** R01H10954412 Biochemistry ol contractile proteins
(animals)
POIHL 1135112 0001 Cellular and molecular
mechanisms of myocardial function - Ionic control of
myocardial contractility (animals)
** POlHL-1135112 0004 Cellular and molecular
mechanisms of myocardial function Molecular
mechanisms of contractile function and differentiation
(animals)
** P01HL1135112 0006 Cellular and molecular
mechanisms ol myocardial function ■ Molecular physiology
and energetics of muscle (frogs)
POIHL 11351 12 0021 Cellular and molecular
mechanisms of myocardial function - Muscle energetics
(frogs)
** POIHL 11351 12 0022 Cellular and molecular
mechanisms of myocardial function - Energetic sequelae of
shortening -Myothermal and biochemical (frogs)
** POIHLI 1351-12 0023 Cellular and molecular
mechanisms of myocardial function Energetics of
mammalian muscle (rats)
•* P01HLn351-12 0024 Cellular and molecular
mechanisms of myocardial function ■ Steady state and
transient kinetics of frog myosin. SI. and ATPase
ROlHL-12186-09 Calcium transients in striated muscle
and other cells (mammals, frogs)
R01HL12494-10 Continuum mechanics in biophysics
(human, animals)
P50HL-1421708 0061 Specialized center of research in
thrombosis - Pharmacology-Comparison of platelets and
vascular smooth muscle (animal)
** POlHL-14388-07 0154 Regulation of the circulation in
pathological states - Energetics of smooth muscle
contraction (rats)
** POlHL-14388-07 0167 Regulation of the circulation in
pathological states - Increased reactivity of artery vascular
muscle in spontaneously hypertensive rat
** ROlHL-14523-07 Generation and regulation of force in
smooth muscle (animals)
POlHL-14985-07 0012 Adaptation to hypoxia - Direct
effect of hypoxia on pulmonary vascular smooth muscle
(rats, dogs)
** ROlHL-15391-07 EPR studies on rotational motion of
myosin and actio
ROlHL-15562-05 Regulation of skeletal muscle blood flow
(dogs)
ROIHL- 15580-06 Humoral control of pulmonary and
systemic circulation (animals)
** ROlHL-15692-07 Force and speed in skeletal and cardiac
muscle
** POlHL-15832-06 0012 Chemical-structural predispositions
to lung injury - Contractile structures and contractility in
cells of lung respiratory tract
M POlHL-15835-06 Study of muscles related to heart
disease
" POlHL-15835-06 0001 Study of muscles related to heart
disease - Control of contraction-relaxation of heart and
muscle (rabbits, chickens)
POlHL-15835-06 0002 Study of muscles related to heart
disease - Proteins of smooth muscle system (cattle,
rabbits)
POlHL-15835-06 0006 Study of muscles related to heart
disease - Ultrastructural and chemical studies of muscle
(animals)
** POlHL-15835-06 0007 Study of muscles related to heart
disease - Structure and function of Limulus striated and
cardiac muscle
POIHL- 1583 5-06 0010 Study of muscles related to heart
disease - Muscle structure and reaction to injury (mice,
rats)
** POlHL-15835-06 0011 Study of muscles related to heart
disease - Energetics and mechanism of muscle contraction
(frogs, rabbits)
** POlHL-15835-06 0012 Study of muscles related to heart
disease - Contraction and energetics of visceral and
vascular smooth muscles (rabbits)
POlHL-15835-06 0018 Study of muscles related to heart
disease - Pharmacology of excitation coupling in muscle
(frog, barnacles)
3Si
•• POIHL 1583506 0019 Study of muscles related lo heart
disease Vascular smooth muscle Electron microscopy,
excitation contraction (animal)
•• POIHL 15835 06 0021 Study ol muscles related lo heart
disease Fast kinetic studies in muscle subcellular
organelles (animals)
ROIHL 1600308 Sources and roles of calcium in smooth
muscle excitation (rats)
ROIHL 16010 16 Cellular basis of cardiac contractility
(frogs)
POIHL 1611705 0002 Ion movements and membranes in
cardiovascular control Fluorescence and excitation
contraction coupling in heart (frogs)
POIHL 16117 05 0003 Ion movements and membranes in
cardiovascular control Fast kinetic study of calcium
membrane interactions
POIHL 16117 05 0006 Ion movements and membranes in
cardiovascular control Neuroreceptors and cellular
excitation (fish)
** POIHL 161 17 05 0008 Ion movements and membranes in
cardiovascular control Arterial smooth muscle calcium
fluxes and contractility (rabbits)
** ROIHL 16454 03 Vascular muscle reactivity in
hypertension (human, rats)
M POIHL 16607-05 Calcium ion and control of
cardiovascular function
POIHL 16607 05 0003 Calcium ion and control of
cardiovascular function Calcium transport in
sarcoplasmic membranes (animals)
** POlHL-16607 05 0006 Calcium ion and control of
cardiovascular function - Sarcomere and contractile
dynamics of striated muscle cells (animals)
*• POlHL-16683 04 0001 Function and growth of cardiac
and skeletal muscle Light chains of the skeletal and
cardiac myosin molecule (rabbits, frogs)
** POlHL-16683-04 0003 Function and growth of cardiac
and skeletal muscle Movements of S-1 moieties in muscle
fibers
** POIHL 16683-04 0006 Function and growth of cardiac
and skeletal muscle Chemical studies of the contractile
system -Development of new reagents
ROlHL-16746-04 Design of ion-selective molecules
POIHL 16910-05 0001 Regulation of the peripheral
circulation - Quantitative studies of microcirculatory control
(bats)
ROlHL-17322-04 Functional characteristics of smooth
muscle isolated from lung (animals)
** ROIHL 17335-05 Contractile properties of hypertensive
arterioles (rats)
** POlHL-17813-04 0006 Lung disease and the oxygenation
of blood and tissue Assessment of respiratory muscle
contractile force (human, dogs)
POlHL-17871-04 0010 Kidney, sodium, cardiac output,
arterioles and hypertension - Renal prostaglandins
metabolism in hypertension (rats, dogs)
ROlHL-18070-04 Regulation of intrapulmonary airways
and vessels (human, animals)
ROlHL-18077-04 Smooth muscle cell organization and
Ca20 concentration control (chickens)
** ROlHL-185 16-03 Atherosclerosis and the arterial
contractile proteins (pigs, rabbits)
ROlHL-18527-03 Subcellular response of heart to
functional overload (hamsters, rats)
POlHL-18575-03 0001 Mechanisms of vascular changes
in hypertension - Arteries and resistance vessels in
hypertension (pigs, rats)
POlHL-18575-03 0007 Mechanisms of vascular changes
in hypertension - Microscopy of hypertensive arterial lesions
(rats)
ROlHL-18831-03 Microscopy of spontaneously hypertensive
arterial lesion (rats)
ROlHL-191 15-02 Hormonal control of tracheobronchial
cyclic AMP (rats, guinea pigs)
M POlHL-19242-02 Study of vascular smooth muscle
P01HL-19242-02 0001 Study of vascular smooth muscle -
Energy metabolism and protein turnover in vascular smooth
muscle (rats)
** POlHL-19242-02 0006 Study of vascular smooth muscle ■
The contractile system of vascular smooth muscle (swine,
rats)
POlHL-19242-02 0009 Study of vascular smooth muscle
Electrophysiology of vascular smooth muscle (rats, chick
embryo)
** ROlHL-19325-03 Phosphodiesterase inhibition and muscle
contraction
ROlHL-19366-03 Renal Starling forces in experimental
conditions (rats, rabbits)
** ROIHL 19848-02 Contractile activation by rapid
temperature jumps (frogs)
** ROlHL-20196-02 Regulation of coronary arterial smooth
muscle
ROlHL-20426-03 Myocardial function in diabetes mellitus
(dog, rat)
ROlHL-20429-03 Study of effects of diabetes reactivity
(miniature pigs, rats)
** ROlHL-20464-01 Regulation of cardiac and skeletal
muscle contraction (mammals)
POlHL-20581-01 0002 Vascular neuroeffector
mechanisms in health and disease - Trophic interaction
between adrenergic nerves and vascular smooth muscle
•Excludes routine methodology OR covers only general projects which preclude
"Oriented significantly to above subject.
indexing at the specific level.
M Grant has subprojects describing si
See Appendix for investigator's name
MUS
POIHI 70581 01 0004 Vascular neuroelfeclor
mechanisms in health and diseate Neuroeffector
characteristics of mosonleric and pulmonary blood vesMli
(rabbits)
POIHL 20592 02 Cell biology of cardiac and skeletal
muscle
POIHI 20592 02 0001 Cell biology ol cardiac and
skeletal muscle Molecular mechanism of muscle
contraction (animals)
POIHL 20592 02 0003 Cell biology of cardiac and
skeletal muscle Cellular magnesium and anion activities
in ion specific microeleclrodes (frogs)
POIHL 20592 02 0004 Cell biology of cardiac and
skeletal muscle Excitation, conduction and contraction
Modelling in Purkinje fibers
POIHL 20592 02 0005 Cell biology of cardiac and
skeletal muscle Quantitative voltage studies
POIHL 20592 02 0006 Cell biology of cardiac and
skeletal muscle Permeability and ultrastructure of cardiac
nexuses (rabbits, cattle, rats)
POIHL 20592 02 0011 Cell biology of cardiac and
skeletal muscle Myosin and cytochrome oxidase
messenger RNAs (chicken)
POIHL 20592-02 0012 Cell biology of cardiac and
skeletal muscle Contractile properties of skinned muscle
fibers (frogs)
ROlHL-20513 02 Mechanical properties of isolated
myocardium
ROlHL-20783-02 Airway reactivity- B adrenoceptors and
prostaglandins (guinea pigs)
ROlHL-20847-02 Respiratory neurochemical control
(human, goats)
■ ROIHL 21103-01 Parametric mechanical studies of
hypertensive arteries (dogs, rats)
' R23HL-21213-01 A model for calcium homeostasis in
excitable tissue (marine worms)
R01HL21239-02 Isolation and mechanism of action of
thromboxane A2 (human, rabbits)
ROlHL-21329-02 Beta-receptor regulation and cardiac
sites of drug action (cat. guinea pig. rat)
' R23HL-2 1409-02 Perinatal control of the ductus arteriosus
(sheep)
' R23HL 21488-01 Myosin-linked regulation in vertebrate
smooth muscle (calf aorta)
* ROlHL-21498-02 Pathophysiology of edema (rats, cats)
* ROlHL-21500-02 Performance of respiratory muscles under
stress (dogs)
ROlHL-21673-01 Pathophysiology of venous changes in
hypertension (rats, rabbits, human, dogs)
ROIHL 21860 18 Factors influencing responses to
adrenergic drugs (guinea pigs. rats, cats)
* R23HL-21914-01 Studies of vasomotor control (rats)
ROlHL-22022-01 Respiratory muscle dyslunction in
respiratory failure (human)
ROlHL-22101-02 Hormone-substrate interaction in diabetic
myocyte (dogs, rats)
* ROlHL-22177-02 Mechanisms ol control ol pulmonary
smooth muscle (dogs)
* ROlHL-22264-01 Regulation ol contraction in vascular
smooth muscle (dogs)
* ROlHL-22461-01 Cardiac tropomyosin and tropomyosin-
action interactions (rabbit)
ROlHL-22538-01 Myosin as a multi-enzyme complex (dogs.
rabbits)
R01HL-22573-01 Treatment ol post surgical
vasoconstriction (dogs, monkeys, human, rats)
* POlHL-22619-01 0008 Cellular mechanisms ol heart
lailure - Molecular mechanisms and diflerential contractile
responsiveness in VSM (dogs)
ROlHL-22910-01 Control ol breathing pattern in health
and disease (human, animals)
R23HL-22984-01 Cyclic AMP dependent protein kinases in
hypertension (rat)
ROlHL-23013-01 Smooth muscle development in vitro
(chick embryo)
R13HL-23072-01 Gordon Research Conlerence -Cardiac and
skeletal muscle (New Hampshire)
'* ROlHL-23205-01 Contraction ol pulmonary vascular
smooth muscle (cat)
ROlHL-23210-01 Biology ol normal and hypertrophied
pulmonary vessels (cat, human)
** ROlHL-23240-01 Pulmonary vascular muscle metabolism
and contractility (rats, cattle)
ROlHL-23249-01 Actin-myosin interaction in pulmonary
smooth muscle (cattle)
** ROlHL-23614-02 Pharmacology ol relaxation in smooth
muscle (mollusks)
** ROlHL-23615-01
(chicken, rabbit)
ROlHL-23980-01
and adult sheep
" ROlHL-23985-01
mechanics (dogs)
MUSCLE FUNCTION, MUSCLE RELAXATION
SEE ALSO MUSCLE RELAXANTS
** POlHL-10539-12 0023 Pathophysiology ol circulation -
The relaxation response and therapy of disease states
(human)
POlHL-10539-12 0031 Pathophysiology of circulation -
Post myocardial infarction care-Psychological aspects
(human)
(conld)
pecific research aspects,
and grant number.
Biochemistry of contractile proteins
Effects of digoxin therapy in newborn
Role of the diaphragm in regional lung
MUS
Diastolic properties of the left ventricle
Mechanical properties of isolated
Right ventricular contraction and
POlHL-10539-12 0064 Pathophysiology of circulation •
Exercise physiology and pathophysiology (human)
** P01HL10539-12 0065 Pathophysiology of circulation -
Physiologic correlates of relaxation (human)
" P01HH0539-12 0066 Pathophysiology of circulation -
Usefulness of relaxation response in industrial settings
POlHL-12373-10 0012 Cardiopulmonary physiology and
pathophysiology • Biochemistry of the sympathetic nervous
system (rats, rabbits, pigeons)
R01HL12711-09 Mathematical approach to cardiovascular
mechanics (human, animals)
ROlHL-14127-16 Methemoglobinemia and antihypertensive
drugs (cats. mice, rats)
P50HL1506107 0005 Response of lung to Injury Airway
smooth muscle in health and disease (dogs, guinea pigs)
R01HL15692-07 Force and speed in skeletal and cardiac
muscle
POlHL-15835-06 0012 Study of muscles related to heart
disease ■ Contraction and energetics of visceral and
vascular smooth muscles (rabbits)
R01HL16606-11 Contraction in heart and other striated
muscles (frogs)
ROIHL 17322-04 Functional characteristics of smooth
muscle isolated from lung (animals)
ROlHL-19082-01 Hypoxla-induced relaxation of vascular
smooth muscle
R01HL-19089-03
(human, dogs)
** ROIHL 19568-03 Hypertension- Analysis of drug and
behavioral therapies (human)
ROlHL-20426-03 Myocardial function in diabetes mellltus
(dog, rat)
** ROlHL-20613-02
myocardium
*• R23HL-21 197-02
relaxation (dogs)
ROlHL-2131201 Sarcomere mechanics In disrupted
ventricular muscle (guinea pigs)
R23HL-21409-02 Perinatal control of the ductus arteriosus
(sheep)
ROlHL-23210-01 Biology of normal and hypertrophled
pulmonary vessels (cat. human)
*• ROlHL-23614-02 Pharmacology of relaxation in smooth
muscle (mollusks)
ROlHL-23990-01 Role of phosphoprotein In cardiac
Inotropic responses
MUSCLE FUNCTION, MUSCLE STRESS
ROlHL-01015-27 Hypertension and left ventricular
hypertrophy (dogs)
POlHL-04664-18 0003 Cardiovascular and lung dynamics
- X-ray projection image videometry (human, dogs)
P01HL04664-18 0004 Cardiovascular and lung dynamics
■ X-ray cross section imaging of the circulation (dogs)
POlHL-08682-15 0005 Regulation of the cardiovascular
system - Smooth muscle and mechanical properties of
blood vessels (dogs, human)
POlHL-1 1310-12 0054 Mechanisms of cardiovascular
disease - Mathematical model of ventricular pressure-
volume (human, dogs)
ROIHL 11876-11 Regional myocardial blood flow and
metabolism (dogs, swine)
POlHL-12373-10 0001 Cardiopulmonary physiology and
pathophysiology ■ Mechanics of myocardial contraction
(dogs, rats, swine)
POlHL-12373-10 0002 Cardiopulmonary physiology and
pathophysiology - Determinants of performance of the
whole heart (dogs)
P01HL13737-07 0007 Assisted circulation -
Determination of cardiac status by use of balloon pump
(dogs)
ROlHL-14545-06 Mechanics of compensatory ventricular
hypertrophy (dogs)
** ROlHL-16236-04 Detailed characteristics of coronary blood
flow (horses, dogs, calves)
ROlHL-17865-04 Studies on aging -Effects of. sex
hormones (rats, dogs)
** R01HL18087-03 Development and regression of cardiac
hypertrophy (rats, rabbits)
POlHL-18575-03 0001 Mechanisms of vascular changes
In hypertension - Arteries and resistance vessels in
hypertension (pigs, rats)
ROlHL-19089-03 Diastolic properties of the left ventricle
(human, dogs)
POlHL-2055202 0002 The development and regression of
cardiac hypertrophy - Effect of treatment on the
hypertrophled left ventricle (rats)
POlHL-20552-02 0004 The development and regression of
cardiac hypertrophy - Ventricular function In experimentally
induced hypertrophy (hogs, sheep, baboons)
POlHL-20552-02 9002 The development and regression of
cardiac hypertrophy - Core B-Biomathematics
R23HL-21234-02 The regulation of cardiac hypertrophy
(rabbits)
ROIHL-21425-02 Servo-simulated compliance changes-A
reversible Ml (dogs)
ROlHL-21500-02 Performance of respiratory muscles under
stress (dogs)
ROlHL-23542-01 Pulmonary vascular smooth muscle cell
dynamics (rat, rabbit)
356
MUSCLE FUNCTION, MUSCLE STRETCH
(RECEPTORS)
ROlHL-02888-22 Interrelationships of circulation and
respiration (opossum, cats)
R01HL06143-18 Response of the totally denervated heart
to exercise (dogs)
POlHL-06296-18 0007 Cardiovascular and pulmonary
adaptation to stress - Cardiovascular control during
Isometric exercise (cats)
POlHL-08682-15 0027 Regulation of the cardiovascular
system - Cardiac mechanoreceptors -Reflex regulation of
renal function (dogs)
POlHL-08805-15 0045 Regulation of ventilation and
pulmonary circulation - Integrated description of
neurochemical respiratory control system
** ROlHL-13623-08 Atrial receptors (dogs)
POlHL-14388-07 0204 Regulation of the circulation in
pathological slates Reflex control of vascular resistance
In spontaneously hypertensive rats
POlHL-14414-07 0007 Environmental influences on
cardiorespiratory and cellular functions ■ Neural control of
respiration (human, cats)
ROlHL-19133-03 Contractile and elastic properties of
cardiac muscle (cats)
ROlHL-22594-01 Reflex control of the circulation in heart
failure (dogs)
MUSCLE FUNCTION, MUSCLE STRETCH REFLEX
SEE ALSO SKELETAL MOVEMENT, POSTURE
POlHL-06285-18 0180 Cardiovascular-respiratory
physiology and biochemistry Vagal C-flbers and their
influence on visceral and somatic function (animals)
POlHL-11351-12 0003 Cellular and molecular
mechanisms of myocardial function Mechanical and
electrical properties of cardiac muscle (rabbits)
ROIHL-12792-09 Local control of the microcirculation
(hamsters, rats)
ROlHL-13427-09 Neural control of blood volume (monkeys,
dogs)
" ROlHL-13623-08 Atrial receptors (dogs)
POlHL-144 14-07 0007 Environmental influences on
cardiorespiratory and cellular functions - Neural control of
respiration (human, cats)
POlHL-15835-06 0012 Study of muscles related to heart
disease - Contraction and energetics of visceral and
vascular smooth muscles (rabbits)
POIHL-20552-02 0001 The development and regression of
cardiac hypertrophy - Biochemical events in cardiac
hypertrophy (rats)
** ROlHL-23542-01 Pulmonary vascular smooth muscle cell
dynamics (rat, rabbit)
MUSCLE FUNCTION, MUSCLE TENSION
POlHL-08682-15 0005 Regulation of the cardiovascular
system - Smooth muscle and mechanical properties of
blood vessels (dogs, human)
*• POlHL-08899-14 0040 Tolerance to respiratory gases in
health and disease - Metabolic gas influence on brain
vascular tissue (animals)
** POIHL-10539-12 0067 Pathophysiology of circulation -
Mechanical, electrophysiological studies -Isolated heart
muscle (dog, rat)
POlHL-1 1307-12 0003 Biophysical studies in pediatric
cardiology - Cellular biophysics (animals)
POlHL-1 13 10-12 0085 Mechanisms of cardiovascular
disease • Mechanics of Isolated cardiac muscle (animals)
POlHL-12373-10 0005 Cardiopulmonary physiology and
pathophysiology - Characterization of fetal and neonatal
myocardium (human, cats)
POlHL-14388-07 0173 Regulation of the circulation In
pathological states - Mechanisms of cardiac myosin ATPase
ROlHL-14523-07 Generation and regulation of force In
smooth muscle (animals)
P50HL-15061-07 0005 Response of lung to injury Airway
smooth muscle in health and disease (dogs, guinea pigs)
POlHL-15835-06 0010 Study of muscles related to heart
disease - Muscle structure and reaction to Injury (mice,
rats)
** POlHL-15835-06 0011 Study of muscles related to heart
disease - Energetics and mechanism of muscle contraction
(frogs, rabbits)
POlHL-15835-06 0012 Study of muscles related to heart
disease Contraction and energetics of visceral and
vascular smooth muscles (rabbits)
** POlHL-1583506 0023 Study of muscles related to heart
disease - Cellular basis of the Frank-Starting curve (frogs,
rats)
ROlHL-160 10-16 Cellular basis of cardiac contractility
(frogs)
POlHL-161 17-05 0005 Ion movements and membranes in
cardiovascular control - Properties of Isolated cell
membranes (rabbits, cats)
ROlHL-161 52-06 Electrophyslology of neonatal to adult
heart (cats, frogs, guinea pigs)
POlHL-16683-04 0003 Function and growth of cardiac
and skeletal muscle - Movements of S-1 moieties in muscle
fibers
ROlHL-16710-03 Myocardial subcellular localization of
calcium (dogs)
** ROlHL-17322-04 Functional characteristics of smooth
muscle Isolated from lung (animals)
♦* ROlHL-1759203 Activation and contraction heat In
enlarged hearts (rabbits)
Contractile activity of single cardiac cells
Contractile activation of skinned cardiac
Vascular smooth muscle in hypertension
MUS
ROlHL-18460-01 Effects of prolonged hypoperfusion on the
myocardium (rabbits)
R01HL-I8676-03 Myocardial sarcomere mechanics (rat)
ROlHL-18900-03 Intercellular factors in function of
cardiac cells
ROlHL-18943-03
ROlHL-19138-03
cells (mammals)
R01HL19226-03
(rats)
POlHL-19737-02 0009 Cellular and molecular aspects of
respiratory physiology ■ Regulation of tissue oxygen tension
and body carbon monoxide stores (human, dogs)
ROlHL-19848-02 Contractile activation by rapid
temperature jumps (frogs)
POlHL-20592-02 0012 Cell biology of cardiac and
skeletal muscle - Contractile properties of skinned muscle
fibers (frogs)
ROlHL-21 145-02 Response of atria to hyperosmolallty-
Mechanisms (rabbits)
ROlHL-21 182-02 Active tension and shortening in cardiac
hypertrophy (rabbits)
R23HL 21234-02 The regulation of cardiac hypertrophy
(rabbits)
ROlHL-21312-01 Sarcomere mechanics in disrupted
ventricular muscle (guinea pigs)
R23HL 21325-02 Sarcomere kinematics in cardiac
contraction (rats, rabbits)
R23HL-21409-02 Perinatal control of the ductus arteriosus
(sheep)
ROlHL-21922-01 Transient currents Induced by
strophanthidin In the heart
ROlHL-22269-01 Excitation-contraction coupling In
enlarged hearts (rabbits)
ROlHL-23205-01 Contraction of pulmonary vascular
smooth muscle (cat)
ROlHL-23240 01 Pulmonary vascular muscle metabolism
and contractility (rats, cattle)
ROlHL-2324501 Adrenergic receptors In pulmonary
vascular muscle (human, animal)
ROlHL-23542-01 Pulmonary vascular smooth muscle cell
dynamics (rat. rabbit)
** ROIHL 23614-02 Pharmacology of relaxation in smooth
muscle (mollusks)
MUSCLE FUNCTION, MUSCLE TONE
ROlHL-08570-15 Pharmacologic and reflex influence on
vascular tone (dogs, rabbits)
P01HL14388-07 0185
pathological states -
rabbits, dogs)
POlHL-14388-07 0198
pathological states
Regulation of the circulation in
Reflex control of venous tone (human,
•Excludes routine methodology OR covers only general proiects which preclude indexing at the specific level
"Onented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigators name and grant number.
Regulation of the circulation in
Humoral factors in vascular reactivity
in spontaneously hypertensive rats
** ROlHL-1580506 Cerebral arterial tone and reactivity
(rabbits)
P50HL-19156-02 0005 Pulmonary SCOR-Chronic diseases
of airways - Vagal receptors In the airway-Epithelial injury
and antigen (dog. cat, rabbit)
ROlHL-19325-03 Phosphodiesterase inhibition and muscle
contraction
** POlHL-19737-02 0002 Cellular and molecular aspects of
respiratory physiology - Airway smooth muscle in health
and disease (human, animals)
ROlHL-20783-02 Airway rcactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
ROlHL-21187-01 Potassium, norepinephrine, and coronary
arterial tone (dogs)
POlHL-21584-02 0005 Respiratory mechanics In normal
and abnormal states - Regulation and behavior of airway
smooth muscle (human, animals)
ROlHL-22177-02 Mechanisms of control of pulmonary
smooth muscle (dogs)
ROlHL-22486-01 Enzyme regulation in cultured arterial
cells (swine)
ROIHL-23210-01 Biology of normal and hypertrophled
pulmonary vessels (cat. human)
ROlHL-23240-01 Pulmonary vascular muscle metabolism
and contractility (rats, cattle)
ROIHL 23245-01 Adrenergic receptors in pulmonaiy
vascular muscle (human, animal)
MUSCLE HYPERTROPHY
POlHL-06285-18 0173 Cardiovascular-respiratory
physiology and biochemistry - Skeletal and cardiac muscle
function
POlHL-16387-04 0003 The blood vessel and
thrombogenesJs - Blood vessel healing (rabbits)
POIHL-16683-04 0001 Function and growth of cardiac
and skeletal muscle - Light chains of the skeletal and
cardiac myosin molecule (rabbits, frogs)
ROlHL-17322-04 Functional characteristics of smooth
muscle isolated from lung (animals)
ROlHL-21312-01 Sarcomere mechanics In disrupted
ventricular muscle (guinea pigs)
R01HL-21970-01 Myofibrillar assembly and breakdown In
cardiac muscle (rats)
MUSCLE METABOUSM
** ROlHL-10018-11 Effect of aging on beating heart cells in
culture (rats)
(contd)
MUS
•• PbOHL 1767004 0022 Study ol ischemic heart disease
Myocardial metabolism in hypoiia and lecovei (labbit.
toad, do|)
P50HL 1767004 0023 Study of ischemic heart disease
Energy metabolism in acute myocardial ischemic iniury
(dots)
•• P50HI 1768204 0020 Study ol ischemic heart disease
Nucleotide and nucleoside metabolism in ischemic
myocardium
ROlHL-2185101 Cerebral microciicuiation in experimental
hypertension (cats, rabbits)
ROlHL-21970 01 Myolibrillar assembly and breakdown in
cardiac muscle (rats)
ROlHL-2313801 Myocardial ischemia (dogs. rats, chick
embryo)
ROIHL 23161 01 0001 Biology of myocardial ischemia
Mitochondrial lipid metabolism and cardiac ischemia (rat.
dog)
ROlHL-2316101 0002 Biology of myocardial ischemia
Palmitylcarnitine inhibition ol ion pumps in myocardial
ischemia (dog, sheep)
ROIHL-23205 01 Contraction of pulmonary vascular
smooth muscle (cat)
ROIHL 2322401 Hypoxia and pulmonary vascular smooth
muscle (rat. cat)
•* ROIHL 2324001 Pulmonary vascular muscle metabolism
and contractility (rats, cattle)
MUSCLE NECROSIS
SEE MUSCULAR DISORDERS. MUSCLE NECROSIS
MUSCLE PHARMACOLOGY
SEE ALSO MUSCLE METABOLISM
SEE ALSO MUSCUUR DISORDERS CHEMOTHERAPY
R01HL05806-18 Analysis of antiarrhythmic agents (dogs,
rabbits)
•* R01HL0928314 Pharmacology of molluscan hearts (also
rabbits)
P01HL11351-12 0011 Cellular and molecular
mechanisms of myocardial function ■ Comparative
contractile tissue studies (animals)
ROIHL- 12 18609 Calcium transients in striated muscle
and other cells (mammals, frogs)
POlHL-14388-07 0178 Regulation of the circulation in
pathological states ■ Structural and functional
consequences of denen/ation (rats)
** PaiHL-14985-07 0012 Adaptation to hypoxia ■ Direct
effect of hypoxia on pulmonary vascular smooth muscle
(rats, dogs)
** P50HL-15061-07 0005 Response of lung to injury - Airway
smooth muscle in health and disease (dogs, guinea pigs)
M POlHL-15835-06 Study of muscles related to heart
disease
POIHL- 1583 5-06 0009 Study of muscles related to heart
disease • Aspects of cardiac and skeletal myogenesis
(chick embryo)
POlHL-15835-06 0010 Study of muscles related to heart
disease - Muscle structure and reaction to injury (mice,
rats)
POlHL-15835-06 0012 Study of muscles related to heart
disease - Contraction and energetics of visceral and
vascular smooth muscles (rabbits)
*• POlHL-15835-06 0018 Study of muscles related to heart
disease - Pharmacology of excitation coupling in muscle
(frog, barnacles)
POlHL-15835-06 0019 Study of muscles related to heart
disease - Vascular smooth muscle -Electron microscopy,
excitation contraction (animal)
R01HL-16710-03 Myocardial subcellular localization of
calcium (dogs)
ROlHL-18676-03 Myocardial sarcomere mechanics (rat)
*• ROlHL-19115-02 Hormonal control of tracheobronchial
cyclic AMP (rats, guinea pigs)
ROlHL-19226-03 Vascular smooth muscle in hypertension
(rats)
M POlHL-19242-02 Study of vascular smooth muscle
" POlHL-19242-02 0004 Study of vascular smooth muscle -
Cyclic nucleotide metabolism in smooth muscle cultures
(human, rats)
POlHL-19242-02 0007 Study of vascular smooth muscle •
NE release in and reactivity of vascular smooth muscle
(animals)
POlHL-19242-02 0008 Study of vascular smooth muscle -
NE release in and reactivity of vascular smooth muscle
(rats)
POlHL-19242-02 0009 Study of vascular smooth muscle -
Electrophysiology of vascular smooth muscle (rats, chick
embryo)
" ROlHL-20184-02 Desensitization of tracheal muscle to
isoproterenol (rats, rabbits)
ROlHL-20749-01 Developing heart -Biophysical aspects
(sheep)
ROlHL-20783-02 Airway reactivity -B-adrenoceptors and
prostaglandins (guinea pigs)
ROlHL-21195-02 Innervation of the heart-Acetylcholine
receptors (frogs)
R23HL-21325-02 Sarcomere kinematics in cardiac
contraction (rats, rabbits)
ROlHL-21570-01 The mechanical basis of myocardial
energetics (cats)
" RUlHL-21670-01 Antiarrhythmic studies on 2-substituted
aminoindenes (dogs)
357
ROIHI 2174? 01 frequency dependent drug actions in
cardiac muscle (rabbits)
R23HI 2257501 Factors modl^lng cardiac digoxin etiecis
and content (dogs, cats)
POIHI 22619 01 0006 Cellular mechanisms of heart
failure Phosphorylation ol contractile proteins in cardiac
muscle contraction (dogs, labb
POIHL 2261901 0008 Cellular mechanisms of heart
failure Molecular mechanisms and differential contractile
responsiveness in VSM (dogs)
•* ROIHL 2320901 Autonomic receptors of the pulmonary
vasculature (mammals)
ROIHL 23210 01 Biology of normal and hypertrophied
pulmonary vessels (cat. human)
ROIHL 23239 01 Functional characteristics ol pulmonary
vascular smooth muscle (dogs)
•* ROIHL 2324501 Adrenergic receptors in pulmonary
vascular muscle (human, animal)
ROlHL-23542 01 Pulmonary vascular smooth muscle cell
dynamics (rat. rabbit)
MUSCLE PROTEINS (AND CONTRACTILE
PROTEINS)
SEE ALSO HEMOPROTEINS. MYOGLOBIN
SEE ALSO PROTEINS. MEMBRANE PROTEINS. SPECTRIN
** ROlHL-05949-18 Biochemistry of muscle contraction (rats.
rabbits)
** POlHL-06285-18 0173 Cardiovascular-respiratory
physiology and biochemistry Skeletal and cardiac muscle
function
** ROlHL-09172 15 Protein and RNA synthesis in heart
muscle (rats)
ROIHL 09562 14 Cardiac protein synthesis, overload,
alcohol and anoxia (guinea pigs)
ROlHL-10018-11 Effect of aging on beating heart cells in
culture (rats)
M POlHL-11351-12 Cellular and molecular mechanisms of
myocardial function
POlHL-1 1351-12 0004 Cellular and molecular
mechanisms of myocardial function - Molecular
mechanisms of contractile function and differentiation
(animals)
POlHL-1 1351-12 0006 Cellular and molecular
mechanisms of myocardial function - Molecular physiology
and energetics of muscle (frogs)
ROlHL-12561-11 Cardiovascular studies on copper
deficiency (swine)
** POlHL-14388-07 0175 Regulation of the circulation in
pathological states - Functional studies of selected proteins
from cardiac muscle
** ROlHL-1539107 EPR studies on rotational motion of
myosin and actin
** ROlHL-15679-06 Heart and smooth muscle contractile
protein (swine, cattle, rabbits, chickens)
** ROlHL-15692-07 Force and speed in skeletal and cardiac
muscle
POIHL- 158 3206 0012 Chemical-structural predispositions
to lung injury - Contractile structures and contractility in
cells of lung respiratory tract
M POlHL-15835-06 Study of muscles related to heart
disease
** POlHL-1583506 0001 Study of muscles related to heart
disease - Control of contraction-relaxation of heart and
muscle (rabbits, chickens)
** POlHL-15835-06 0002 Study of muscles related to heart
disease - Proteins of smooth muscle system (cattle,
rabbits)
** POlHL-15835-06 0006 Study of muscles related to heart
disease - Ultrastructural and chemical studies of muscle
(animals)
POlHL-15835-06 0010 Study of muscles related to heart
disease - Muscle structure and reaction to injury (mice,
rats)
** ROlHL-16637-04 Development and regression of cardiac
hypertrophy (rats)
** ROlHL-16678-03 Fluorescent probe studies of heart
muscle proteins (rabbit, dog)
M POlHL-16683-04 function and growth of cardiac and
skeletal muscle
ROlHL-17376-04 Analysis of Z bands in heart by optical
diffraction (mammals)
R01HL-I7592-03 Activation and contraction heat in
enlarged hearts (rabbits)
ROlHL-18077-04 Smooth muscle cell organization and
Ca20 concentration control (chickens)
** ROlHL-18551-03 Spectrin, actin. lipid and red cell
membrane structure
POlHL-18708-03 0008 Oxygen, energy and contractility in
cardiac tissue - Cardiac cell culture facility
ROlHL-18824-03 Mechanisms of heart failure in
myopathic hamster
ROlHL-190 12-03 Smooth muscle of resistance vessels in
hypertension (rats)
ROlHL-19226-03 Vascular smooth muscle in hypertension
(rats)
ROlHL-19429-03 Phagocytosis-lngestion in alveiolar
macrophages (rabbits)
" ROlHL-19648-03
rabbits)
•Excludes routine methodology OR covers only general projects which preclude
"Onented significantly to above subject,
" ROlHL-20666-02
(human)
ROlHL-20695-02
indexing at the specific level.
Myocardial protein degradation (dogs.
Cell biology of platelet preservation
Stored plateletes (human)
MUS
ROIHL 20902 02 Studies on marginal band -.y^tem ol
erythrocytes (amphibians, reptile-., Iish)
POIHI 20984 02 Cellular mechanisms in cardiac
hypertrophy
POIHI ?0984 02 0001 Cellular mechanisms m cardiar
hypertrophy Contractile proteins in cardiac hypertrophy
(rabbits, calves)
POIHI 20984 02 9001 Cellular mechanisms in cardiac
hypertrophy Animal models and preparation of contractile
proteins
ROIHI 21096 02 Sickle cell crisis Role ol the erythrocyte
membrane (human)
R23HL21128 02 ATP utilization in platelet contractile
mechanisms (human, rabbits)
ROIHL 21469 01 Active transport and effect of CAOO in
sickle cell (human)
ROIHL 21970 01 Myofibrillar assembly and breakdown in
cardiac muscle (rats)
ROlHL-21988 01
chemotaxis
Biochemistry of human platelet
;,jidi3c energy metabolism and protein
Genetic cardiomyopathies in salamanders
synthesis (mice)
ROIHL 22550-02
and hamsters
POIHI 22619-01 Cellular mechanisms of heart failure
POlHL-22619-01 0007 Cellular mechanisms of heart
failure Regulation of contractile protein levels in heart
muscle (rats)
POIHL 22619-01 0008 Cellular mechanisms of heart
failure Molecular mechanisms and differential contractile
responsiveness in VSM (dogs)
POlHL-226 19-01 0010 Cellular mechanisms of heart
failure Mitochondria in heart and smooth muscle (rabbits,
rats, dogs)
ROIHL 22651-01 Control of protein metabolism in heart
muscle
ROIHL 23128-01 Cardiac contractility -Ischemia and
hypoxia (rabbits, rats)
ROlHL-23161-01 0004 Biology of myocardial ischemia
Structure of myofibrils and membranes in early ischemia
(dogs, rabbit, rodents)
' ROlHL-23233-01
structure (cattle)
ROlHL-23587 01
(guinea pigs)
ROlHL-23615-01
(chicken, rabbit)
Pulmonary artery intermediate filament
Phosphorylation of myocardial protein
Biochemistry of contractile proteins
MUSCLE PROTEINS (AND CONTRACTILE
PROTEINS), ACTIN
ROlHL-05949-18 Biochemistry of muscle contraction (rats,
rabbits)
P01HL06285-18 0173 Cardiovascular-respiratory
physiology and biochemistry - Skeletal and cardiac muscle
function
POlHL-06314-17 0047 Immunologic mechanisms in
cardiovascular disease - Role of intravascular coagulation
(human, animals)
POlHL-11351-12 0022 Cellular and molecular
mechanisms of myocardial function - Energetic sequelae of
shortening-Myothermal and biochemical (frogs)
ROlHL-14020-06 Characterization of myosin from blood
platelets (rabbit)
ROlHL-14717-06 Hemodynamics and heart structure-
Ventricular overload (dogs)
ROlHL-1493806 Contractile proteins of heart muscle
(dogs, rabbits)
ROlHL-15391-07 EPR studies on rotational motion of
myosin and actin
ROlHL-15679-06 Heart and smooth muscle contractile
protein (swine, cattle, rabbits, chickens)
ROlHL-15692-07 Force and speed in skeletal and cardiac
muscle
POlHL-15835-06 0001 Study of muscles related to heart
disease - Control of contraction-relaxation of heart and
muscle (rabbits, chickens)
POlHL-15835-06 0004 Study of muscles related to heart
disease - Actomyosin systems and cell motility (slime
molds, human)
POlHL-15835-06 0009 Study of muscles related to heart
disease - Aspects of cardiac and skeletal myogenesis
(chick embryo)
POlHL-15835-06 0025 Study of muscles related to heart
disease - Cellular biology of vascular smooth muscle
(guinea pig)
ROlHL-16678-03 Fluorescent probe studies of heart
muscle proteins (rabbit, dog)
POlHL-16683-04 0001 Function and growth of cardiac
and skeletal muscle - Light chains of the skeletal and
cardiac myosin molecule (rabbits, frogs)
** POlHL-16683-04 0002 Function and growth of cardiac
and skeletal muscle - Myosin, actin, ATP, interaction in
solution
POlHL-16683-04 0006
and skeletal muscle
Function and growth of cardiac
Chemical studies of the contractile
system -Development of new reagents
ROlHL-18030-04 The role of contractile proteins in
platelets (human, rabbits)
ROlHL-18077-04 Smooth muscle cell organization and
Ca20 concentration control (chickens)
ROlHL-18179-03 Heart, platelet, and muscle myosins and
actomyosins (cattle)
(contd)
M Grant has subprojects descnbing specific research aspects.
See Appendix tor investigator's name and grant number.
MUS
P01HL18208-04 0007 Center for the study of blood cell
Theology RBC membrane protein (human)
ROlHL-18516-03 Atherosclerosis and the arterial
contractile proteins (pigs, rabbits)
ROlHL-18551-03 Spectrin, actin, lipid and red cell
membrane structure
P01HL19242-02 0006 Study of vascular smooth muscle
The contractile system of vascular smooth muscle (swine
rats)
ROlHL-19429-03 Phagocytosis-lngestion in alveiolar
macrophages (rabbits)
** ROlHL-2010602 Coupling of platelet contractile proteins
to fibrin (human)
ROlHL-20464-01 Regulation of cardiac and skeletal
muscle contraction (mammals)
ROlHL-2066602 Cell biology of platelet preservation
(human)
ROlHL-20695-02 Stored plateletes (human)
POlHL-20984-02 0003 Cellular mechanisms in cardiac
hypertrophy ■ Fast-kinetics of myosin ATPase from normal
and hypertrophied heart (rabbits)
R23HL-2n2802 ATP utilization in platelet contractile
mechanisms (human, rabbits)
ROlHL-2146901 Active transport and effect of CAOO in
sickle cell (human)
•* R01HL-21471-02 Structure-function studies on actin and
myosin (human, protozoa, rabbits, cattle)
R23HL-21488-01 Myosin-linked regulation in vertebrate
smooth muscle (calf aorta)
ROlHL-21670-01 Antiarrhythmic studies on 2-substituted
aminoindenes (dogs)
ROlHL-22231-02 Modulation of calcium control of cardiac
myofibrils (rats)
** ROlHL-22264-01 Regulation of contraction in vascular
smooth muscle (dogs)
ROlHL-22461-01 Cardiac tropomyosin and tropomyosin-
action interactions (rabbit)
ROlHL-22845-01 Response of cardiac myosin to
hypertrophic stress (rabbits)
ROlHL-23200-01 Isolation of CA binding proteins from
erythrocytes (human)
ROlHL-23205-01 Contraction of pulmonary vascular
smooth muscle (cat)
** ROlHL-23249-01 Actin-myosin interaction in pulmonary
smooth muscle (cattle)
ROlHL-236 15-01 Biochemistry of contractile proteins
(chicken, rabbit)
R01H1.-23994-01 Biochemical properties of human cardiac
myosin
MUSCLE PROTEINS (AND CONTRACTILE
PROTEINS), ALPHA-ACTININ
ROlHL-15679-06 Heart and smooth muscle contractile
protein (swine, cattle, rabbits, chickens)
MUSCLE PROTEINS (AND CONTRACTILE
PROTEINS), ACTOMYOSIN
*♦ ROlHL-01803-23 0017 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Contractile and relaxing proteins of blood
vessels and platelets (mammals, human)
ROlHL-03290-22 Controls of cardiac and vascular smooth
muscles (cats, rats, dogs)
POlHL-13262-07 0011 Arterial wall in atherosclerosis •
Role of hypertension in atherosclerosis (human, monkey,
dog)
ROIHL- 14020-06 Characterization of myosin from blood
platelets (rabbit)
ROlHL-15391-07
myosin and actin
R01HL1549806
(rats)
POlHL-15596-05 0012 Coagulation, fibrinolysis,
hemostasis and hepatitis - Platelet function -Phorbol ester
and zymosan-induced release activity
R01HL-I5799-04 Effect of anesthetics on myocardial
function (cats)
** POlHL-1583506 0004 Study of muscles related to heart
disease - Actomyosin systems and cell motility (slime
molds, human)
P50HL- 17682-04 0024 Study of ischemic heart disease -
Phosphorylation of cardiac contractile proteins during
ischemia (rat, guinea pig)
** ROlHL-18179-03 Heart, platelet, and muscle myosins and
actomyosins (cattle)
ROlHL-18516-03 Atherosclerosis and the arterial
contractile proteins (pigs, rabbits)
** POIHL18708-03 0007 Oxygen, energy and contractility in
cardiac tissue - Surfaces, energy requirements, and
contractile proteins of cardiac cell in vitro
ROlHL-20196-02 Regulation of coronary arterial smooth
muscle
** POlHL-20592-02 0001 Cell biology of cardiac and
skeletal muscle - Molecular mechanism of muscle
contraction (animals)
** ROlHL-2071802 Microstructural integrity of stored human
platelets
ROlHL-21014-01 Mechanism of the inotropic action of
cardiac glycosides
R23HL-21413-02 Structure and function of platelet
calcium-binding protein (human)
R01HL-2147I-02 Structure-function studies on actin and
myosin (human, protozoa, rabbits, cattle)
EPR studies on rotational motion of
Effects of physical training on heart
Biochemistry of contractile proteins
358
ROlHL-22194-02 Allosteric function of platelet contractile
proteins (human)
ROlHL-22401-01 Regulation of tension and active state in
the heart
" POlHL-226 19-01 0005 Cellular mechanisms of heart
failure - Molecular mechanism of regulation of cardiac
muscle contraction (cattle)
ROlHL-23249-01 Actin-myosin interaction in pulmonary
smooth muscle (cattle)
ROlHL-23587-01 Phosphorylation of myocardial protein
(guinea pigs)
ROlHL-23990-01 Role of phosphoprotein in cardiac
inotropic responses
MUSCLE PROTEINS (AND CONTRACTILE
PROTEINS), MEROMYOSIN
POlHL-06285-18 0173 Cardiovascular-respiratory
physiology and biochemistry - Skeletal and cardiac muscle
function
ROlHL-15391-07 EPR studies on rotational motion of
myosin and actin
ROlHL-15692-07 Force and speed in skeletal and cardiac
muscle
POlHL-1 5835-06 0006 Study of muscles related to heart
disease - Ultrastructural and chemical studies of muscle
(animals)
POlHL-15835-06 0009 Study of muscles related to heart
disease Aspects of cardiac and skeletal myogenesis
(chick embryo)
ROlHL-16678-03 Fluorescent probe studies of heart
muscle proteins (rabbit, dog)
POlHL-18708-03 0007 Oxygen, energy and contractility in
cardiac tissue - Surfaces, energy requirements, and
contractile proteins of cardiac cell in vitro
ROlHL-23249-01 Actin-myosin interaction in pulmonary
smooth muscle (cattle)
MUSCLE PROTEINS (AND CONTRACTILE
PROTEINS), MYOSIN
SEE ALSO PHOSPHATASES, ADENOSINE TRIPHOSPHATASE
ROlHL-05949-18 Biochemistry of muscle contraction (rats,
rabbits)
POlHL-06285-18 0173 Cardiovascular-respiratory
physiology and biochemistry - Skeletal and cardiac muscle
function
** ROlHL-06924-16 Humoral and metabolic aspects of
cardiac function (mammals, non-human, human)
ROlHL-091 72-15 Protein and RNA synthesis in heart
muscle (rats)
ROlHL-09544-12
(animals)
ROlHL-09562-14 Cardiac protein synthesis, overload,
alcohol and anoxia (guinea pigs)
POlHL-11351-12 0004 Cellular and molecular
mechanisms of myocardial function - Molecular
mechanisms of contractile function and differentiation
(animals)
POlHL-1 1351-12 0006 Cellular and molecular
mechanisms of myocardial function - Molecular physiology
and energetics of muscle (frogs)
** POlHL-1 1351-12 0024 Cellular and molecular
mechanisms of myocardial function - Steady state and
transient kinetics of frog myosin, S-1, and ATPase
ROlHL-13831-08 Factors regulating embryonic cardiac
morphogenesis (chick, salamandra)
ROlHL-14020-06 Characterization of myosin from blood
platelets (rabbit)
** P50HL-142 12-07 0007 Correlated studies of pulmonary
fibrosis - Protein metabolism in alveolar macrophages
(rabbits, guinea pigs, human)
** POlHL-14388-07 0173 Regulation of the circulation in
pathological states - Mechanisms of cardiac myosin ATPase
ROlHL-14938-06 Contractile proteins of heart muscle
(dogs, rabbits)
ROlHL-15391-07 EPR studies on rotational motion of
myosin and actin
ROlHL-15498-06 Effects of physical training on heart
(rats)
ROlHL-15692-07
muscle
ROlHL-15799-04
function (cats)
POlHL-15835-06 0001 Study of muscles related to heart
disease - Control of contraction-relaxation of heart and
muscle (rabbits, chickens)
" POlHL-15835-06 0002 Study of muscles related to heart
disease - Proteins of smooth muscle system (cattle,
rabbits)
POIHL-15835-06 0004 Study of muscles related to heart
disease - Actomyosin systems and cell motility (slime
molds, human)
** POlHL-15835-06 0006 Study of muscles related to heart
disease - Ultrastructural and chemical studies of muscle
(animals)
POlHL-15835-06 0007 Study of muscles related to heart
disease - Structure and function of Limulus striated and
cardiac muscle
POlHL-15835-06 0009 Study of muscles related to heart
disease - Aspects of cardiac and skeletal myogenesis
(chick embryo)
POlHL-15835-06 0010 Study of muscles related to heart
disease Muscle structure and reaction to injury (mice,
rats)
Force and speed in skeletal and cardiac
Effect of anesthetics on myocardial
MUS
POl ML- 15835-06 0025 Study of muscles related to heart
disease - Cellular biology of vascular smooth muscle
(guinea pig)
P01HL-I6683-04 0001 Function and growth of cardiac
and skeletal muscle - Light chains of the skeletal and
cardiac myosin molecule (rabbits, frogs)
POlHL-16683-04 0002 Function and growth of cardiac
and skeletal muscle - Myosin, actin, ATP, interaction in
solution
POlHL-16683-04 0003
and skeletal muscle
fibers
POIHL- 16683-04 0006
and skeletal muscle
Function and growth of cardiac
Movements of S-1 moieties in muscle
Function and growth of cardiac
- Chemical studies of the contractile
system -Development of new reagents
ROlHL-16938-05 Effect of physical forces on blood (dogs,
human)
P60HL-1 7269-04 0007 National heart and blood vessel
research and demonstration center - Correlative studies of
experimental myocardial ischemia (dog)
ROlHL-17592-03 Activation and contraction heat in
enlarged hearts (rabbits)
R01HL17631-05 Experimental congestive heart failure and
hypertrophy (cats)
P50HL-1 7648-04 0025 Study of ischemic heart disease -
Destruction and repair of cardiac muscle cell constituents
(rat)
P50HL- 17648-04 0026 Study of ischemic heart disease -
Control of muscle cell proliferation (organ culture)
* P50HL- 17665-04 0011 Study of ischemic heart disease -
Development of new methods for the determination of
infarct size (dog, human)
P50HL-1 7665-04 0028 Study of ischemic heart disease -
Pathologic and biochemical studies of ischemic
myocardium (human, dog)
* P50HL-17665-04 0032 Study of ischemic heart disease ■
Myocardial infarct sizing -Immunoassay for cardiac myosin
light chains (dogs)
* P50HL- 17669-04 0002 Ischemic heart disease center
(SCOR) - Myocardial infarction sizing by radioimmunoassay
of cardiac myosin (dogs)
ROIHL- 18030-04 The role of contractile proteins In
platelets (human, rabbits)
ROlHL-18077-04 Smooth muscle cell organization and
Ca20 concentration control (chickens)
ROlHL-18176-02 Effect of thyroid hormone on cultured
cardiac cells (rats)
* ROlHL-18179-03 Heart, platelet, and muscle myosins and
actomyosins (cattle)
ROlHL-18516-03 Atherosclerosis and the arterial
contractile proteins (pigs, rabbits)
ROlHL-18527-03 Subcellular response of heart to
functional overload (hamsters, rats)
P50HL-18828-03 0001 Specialized center of research In
thrombosis - Membrane biology and hemostasis (human)
POlHL-19242-02 0006 Study of vascular smooth muscle -
The contractile system of vascular smooth muscle (swine,
rats)
ROlHL-19425-03 Cardiac function in hypertrophy (dog)
ROlHL-19429-03 Phagocytosis-lngestion in alveiolar
macrophages (rabbits)
ROlHL-19461-03 Myocardial energetics in hypertrophy and
heart failure (rabbits)
■ R01HL-20106-02 Coupling of platelet contractile proteins
to fibrin (human)
ROlHL-20388-03 Regulation of protein turnover in diabetic
heart (rat)
ROlHL-20464-01 Regulation of cardiac and skeletal
muscle contraction (mammals)
POlHL-20592-02 0001 Cell biology of cardiac and
skeletal muscle - Molecular mechanism of muscle
contraction (animals)
■ POlHL-20592-02 0011 Cell biology of cardiac and
skeletal muscle - Myosin and cytochrome oxidase
messenger RNAs (chicken)
ROlHL-20666-02 Cell biology of platelet preservation
(human)
POlHL-20984-02 0001 Cellular mechanisms in cardiac
hypertrophy - Contractile proteins in cardiac hypertrophy
(rabbits, calves)
POlHL-20984-02 0002 Cellular mechanisms in cardiac
hypertrophy - Thermodynamic, fluorescence, chemical
modification of hypertrophied heart myosin
POlHL-20984-02 0003 Cellular mechanisms in cardiac
hypertrophy Fast-kinetics of myosin ATPase from normal
and hypertrophied heart (rabbits)
R23HL-21 128-02 ATP utilization in platelet contractile
mechanisms (human, rabbits)
R23HL-21234-02 The regulation of cardiac hypertrophy
(rabbits)
ROlHL-21471-02 Structure-function studies on actin and
myosin (human, protozoa, rabbits, cattle)
R23HL-21488-01 Myosin-linked regulation in vertebrate
smooth muscle (calf aorta)
ROlHL-21670-01 Antiarrhythmic studies on 2-substrtuted
aminoindenes (dogs)
R01HL-2I751-02 Thallium and antimyosin in ischemia and
infarction
Thallium and antimyosin in
In vitro models of ischemia and
ROlHL-21751-02 0001
ischemia and infarction
infarction (rats, mice)
•Excludes routine methodology OR covers only general projects which preclude indexing
"Oriented significantly to above subject.
at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
(contd)
:^ssss^.
MUS
359
MUS
Thallium and antimycsin in
Canine models ol Ischemia and
Thallium and antimynsin in
' Human ttudiaS'lschemia and
Regulation ot tension and active stale In
Myosin as a multi-enzyme complex (dogs.
Phosphorylation ol myocardial protein
Biochemistry ot contractile proteins
ROIHI 21751 02 0002
ischenila and inlarction
Inlacction
R01H12W51 02 0003
ischemia and inlirction
inlarction
" ROIHL 21820-01 Regulatory role of myosin in cardiac
hypertrophy (dogs)
ROIHI 22231 02 Modulation ol calcium control ol cardiac
myofibrils (rats)
•* ROIHI 22264 01 Regulation ol contraction in vascular
smooth muscle (dogs)
ROlHl-22361-01 Regulation ol cardiac adaptation to
exercise (rats)
•* ROlHL-22401-01
the heart
•• R01HL2253801
rabbits)
*• POlHL-22619-01 0006 Cellular mechanisms ot heart
lailure Phosphorylation ol contractile proteins in cardiac
muscle contraction (dogs, rabb
POlHl-22619-01 0008 Cellular mechanisms ol heart
failure - Molecular mechanisms and diHerential contractile
responsiveness in VSM (dogs)
*• ROlHL-2284501 Response ol cardiac myosin to
hypertrophic stress (rabbits)
ROlHL-23205-01 Contraction ol pulmonary vascular
smooth muscle (cat)
ROlHL-2323201 EHect ol hypoxia on PVSM and its
precursor cells
•* ROlHL-23249-01 Actin-myosin interaction in pulmonary
smooth muscle (cattle)
ROlHL-23587-01
(guinea pigs)
R01HL-23615-01
(chicken, rabbit)
ROlHL-23990-01 Role ol phosphoprotein in cardiac
inotropic responses
** ROlHL-23994-01 Biochemical properties of human cardiac
myosin
MUSCLE PROTEINS (AND CONTRACTILE
PROTEINS), PARAMYOSIN
** POlHL-15835-06 0007 Study ol muscles related to heart
disease - Structure and lunction ol Limulus striated and
cardiac muscle
MUSCLE PROTEINS (AND CONTRACTILE
PROTEINS), TROPOMYOSIN
SEE ALSO MUSCLE PROTEINS (AND CONTRACTILE PROTEINS).
TROPONIN
** ROlHL-01803-23 0017 Arteriosclerosis, glomerulonephritis,
rheumatic lever - Contractile and relaxing proteins ol blood
vessels and platelets (mammals, human)
ROlHL-05949-18
rabbits)
ROlHL-09544-12
(animals)
R01HL1493806 Contractile proteins ol heart muscle
(dogs, rabbits)
ROlHL-15679-06 Heart and smooth muscle contractile
protein (swine, cattle, rabbits, chickens)
ROlHL-15692-07 Force and speed in skeletal and cardiac
muscle
ROlHL-15799-04 Effect ol anesthetics on myocardial
lunction (cats)
POlHL-15835-06 0001 Study of muscles related to heart
disease - Control of contraction-relaxation of heart and
muscle (rabbits, chickens)
P01HL15835-06 0009 Study of muscles related to heart
disease - Aspects of cardiac and skeletal myogenesis
(chick embryo)
ROlHL-16678-03 Fluorescent probe studies of heart
muscle proteins (rabbit, dog)
ROlHL-16706-04 Excitation-contraction coupling and heart
failure (dogs, rabbits)
ROlHL-18030-04 The role of contractile proteins in
platelets (human, rabbits)
ROlHL-18077-04 Smooth muscle cell organization and
Ca20 concentration control (chickens)
** ROlHL-18612-03 Thin filament control of heart contraction
(cattle)
ROlHL-20464-01 Regulation of cardiac and skeletal
muscle contraction (mammals)
ROlHL-21014-01 Mechanism of the inotropic action of
cardiac glycosides
** ROlHL-22461-01 Cardiac tropomyosin and tropomyosin-
action interactions (rabbit)
ROlHL-22651-01 Control of protein metabolism in heart
muscle
R01HL-23200-01 Isolation of CA binding proteins from
erythrocytes (human)
ROlHL-23249-01 Actin-myosin interaction in pulmonary
smooth muscle (cattle)
ROlHL-23587-01 Phosphorylation of myocardial protein
(guinea pigs)
ROlHL-236 15-01 Biochemistry of contractile proteins
(chicken, rabbit)
MUSCLE PROTEINS (AND CONTRACTILE
PROTEINS), TROPONIN
R01HL-03290-22 Controls of cardiac and vascular smooth
muscles (cats. rats, dogs)
Biochemistry of muscle contraction (rats.
Biochemistry of contractile proteins
Biochemistry of muscle contraction (rats.
Protein and RNA synthesis in heart
Biochemistry ol contractile proteins
Effect of anesthetics on myocardial
ROIHL 05949 18
rabbits)
ROIHI 091/2 15
muscle (rats)
ROIHL 09544 12
(animals)
POIHL 11351 12 0004 Cellular and molecular
mechanisms of myocardial function Molecular
mechanisms ol contractile function and differentiation
(animals)
ROIHL 1493806 Contractile proteins of heart muscle
(dogs, rabbits)
R01HL15799 04
lunction (cats)
POIHL 1583506 0001 Study ol muscles related to heart
disease Control ol contraction-relaxation ol heart and
muscle (rabbits, chickens)
ROIHL 16678 03 Fluorescent probe studies ol heart
muscle proteins (rabbit, dog)
ROIHL 17631 05 Experimental congestive heart lailure and
hypertrophy (cats)
■* P50HL 17682 04 0024 Study of ischemic heart disease
Phosphorylation ol cardiac contractile proteins during
ischemia (rat. guinea pig)
ROIHL 18280-03 Regulation ot cardiac contractility and
metabolism (rats)
•* ROlHL-18612-03 Thin tilameni control ol heart contraction
(cattle)
** ROlHL-20464-01 Regulation ol cardiac and skeletal
muscle contraction (mammals)
ROlHL-21014-01 Mechanism ol the inotropic action ol
cardiac glycosides
R23HL21413 02 Structure and lunction ol platelet
calcium-binding protein (human)
ROIHL 21670-01 Antiarrhythmic studies on 2-substifuted
aminoindenes (dogs)
ROlHL-22231-02 Modulation ol calcium control ol cardiac
myolibrils (rats)
ROlHL-22461-01 Cardiac tropomyosin and tropomyosin-
action interactions (rabbit)
*• POlHL-226 19-01 0005 Cellular mechanisms ol heart
lailure - Molecular mechanism ol regulation ol cardiac
muscle contraction (cattle)
*• POlHL-226 19-01 0006 Cellular mechanisms ol heart
lailure Phosphorylation ol contractile proteins in cardiac
muscle contraction (dogs, rabb
** POlHL-226 19-01 0007 Cellular mechanisms ol heart
lailure - Regulation ol contractile protein levels in heart
muscle (rats)
ROlHL-22651-01 Control ol protein metabolism in heart
muscle
ROlHL-23200-01 Isolation ol CA binding proteins Irom
erythrocytes (human)
ROlHL-23587-01
(guinea pigs)
ROlHL-236 15-01
(chicken, rabbit)
ROlHL-23990-01
inotropic responses
MUSCLE RELAXANTS
POlHL-06296-18 0005 Cardiovascular and pulmonary
adaptation to stress - Regulation ol ventricular
performance (animals)
POlHL-06664-17 0010 Cardiopulmonary lunction in
remediable vascular disease - Ischemia and acute renal
lailure (rats)
** POlHL-07896-15 0056 Environmental biomedical research
program - Neuromuscular blocking effects of
nondepolarizing muscular relaxants (frogs)
ROlHL-09914-13 The myocardium in diabetes mellitus
(dogs, monkeys)
ROlHL-124 15-10 Evaluation of left ventricular lunction
(dogs, rabbits)
P01HL-12738-10 0109 Physiologic pharmacology and its
clinical applications - Elfects ol calcium blockers on
skeletal and cardiac muscle (cats)
P50HL-14187-07 0012 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses - Vasoactive
mediators in pulmonary disease (human, animal)
ROlHL-14903-07 A nev» index ol cardiac contractility
(human, dogs, baboons)
ROlHL-15764-05 CAMP dependent protein kinase in
cardiac contraction (dogs)
POlHL-15835-06 0012 Study ol muscles related to heart
disease - Contraction and energetics ol visceral and
vascular smooth muscles (rabbits)
R01HL-16436-04
lunction (rats)
R01HL-16710-03
Phosphorylation ol myocardial protein
Biochemistry of contractile proteins
Role of phosphoprotein in cardiac
Role of calcium and thyroxine in heart
Myocardial subcellular localization of
calcium (dogs)
ROlHL-17629-03 Developmental aspects of cardiovascular
function (human, cats, rabbits)
ROlHL-17796-04 Importance ol aminosugars in digitalis
activity (cats, rabbits)
ROlHL-18260-04
tissue (cattle)
ROlHL-18517-03
ROlHL-206 13-02
myocardium
ROlHL-20783-02
prostaglandins (guinea pigs)
Cyclic nucleotide metabolism in lung
Intrinsii, innervation of the heart (dogs)
Mechanical properties of isolated
Airway reactivity-B-adrenoceptors and
POIHI 20984 02 0005 Cellular mechenumi m cardiac
hypertrophy Neurohumoral receptors in cardiac growth
and compensatory hypertrophy (animal*)
ROIHI 21014 01 Mechanism ol the inotropic action ol
cardiac glycosides
R23HI 21325 02 Sarcomere kinematics in cardiac
contraction (rats, rabbits)
ROIHI 21329 0? Beta receptor regulation and cardiac
sites of drug action (cat. guinea pig. rat)
ROIHI 2157001
energetics (cats)
ROIHI 2213602
ROIHL 22231 02
myofibrils (rats)
ROIHL 2226901
The mechanical basis ol myocardial
Histamine and cardiac adenyl cyclase
Modulation ol calcium control ol cardiac
Excitation contraction coupling in
enlarged hearts (rabbits)
R23HL 2230901 Cardiovascular pharmacodynamics in
immature dogs
ROIHL 22566-01 Mesoionic purinones as
phosphodiesterase inhibitors
POIHL 22619-01 0006 Cellular mechanisms ol heart
lailure Phosphorylation ol contractile proteins in cardiac
muscle contraction (dogs, rabb
ROIHL 22685 01 Drugs and excitation contraction coupling
in heart (animals)
ROIHL 23209 01 Autonomic receptors ot the pulmonary
vasculature (mammals)
ROlHL-2324501 Adrenergic receptors in pulmonary
vascular muscle (human, animal)
ROlHL-23990-01 Role ol phosphoprotein in cardiac
inotropic responses
MUSCLE RELAXANTS, ANTISPASMODICS
ROlHL-20184-02 Desensitization of tracheal muscle to
isoproterenol (rats, rabbits)
MUSCLE RELAXANTS, NEUROMUSCULAR
BLOCKING AGENTS
** POlHL-07896 15 0056 Environmental biomedical research
program Neuromuscular blocking effects of
nondepolarizing muscular relaxants (frogs)
R23HL-21405 01 Respiratory muscles in regulation of
infant breathing (human)
ROlHL-23614-02 Pharmacology of relaxation in smooth
muscle (mollusks)
MUSCLE RELAXANTS, NEUROMUSCULAR
BLOCKING AGENTS DEPOLARIZING
** ROlHL-17452-04 Depolarization induced cardiac
automaticity (human, animals)
MUSCLE RELAXATION
SEE MUSCLE FUNCTION. MUSCLE RELAXATION
MUSCLE STIMULANTS
POlHL-06285-18 0155 Cardiovascular-respiratory
physiology and biochemistry Therapeutic alterations,
contractile state in heart failure
POlHL-06296-18 0005 Cardiovascular and pulmonary
adaptation to stress - Regulation of ventricular
performance (animals)
POlHL-06664-17 0034 Cardiopulmonary function in
remediable vascular disease - Role ol hyperosmolar agents
in ischemic heart disease (dogs)
ROlHL-08659-14 Myocardial performance and metabolism
in the newborn (sheep)
ROlHL-10897-12 Elfects ol hormones on cardiac
electrogenesis (rabbits, guinea pigs, dogs)
POlHL-11307-12 0003 Biophysical studies in pediatric
cardiology - Cellular biophysics (animals)
POlHL-11310-12 0068 Mechanisms of cardiovascular
disease - Pharmacological intervention and myocarcial
oxygen consuption (human, dogs)
POlHL-1131012 0086 Mechanisms of cardiovascular
disease - Mechanics of the intact left ventricle (dogs)
POlHL-11351-12 0010 Cellular and molecular
mechanisms of myocardial function - Basic ionic exchange
studies (rats)
POlHL-12373-10 0013 Cardiopulmonary physiology and
pathophysiology - Effects of cardiovascular drugs on left
ventricular function (dogs)
ROIHL-12774-08 Ionic coupling in activation of cardiac
muscle (frogs, guinea pigs)
R01HL-13639-07 Factors altering the course of myocardial
dysfunction (cats)
R01HL14545-06 Mechanics of compensatory ventricular
hypertrophy (dogs)
ROlHL-14903-07 A new index of cardiac contractility
(human, dogs, baboons)
ROlHL-15522-06 Influence of mannitol on ischemia
cardiac muscle (dogs. cats, rats)
ROlHL-15758-06 Catecholamine release in the heart
(dogs)
POIHL- 15835-06 0012 Study of muscles related to heart
disease - Contraction and energetics of visceral and
vascular smooth muscles (rabbits)
** ROlHL-15991-05 Evaluation of heart stimulants in sea
anemones
** ROlHL-16052-05 Cardiac glycosides -Mechanism of
inotropic action (dogs)
POIHL 16117-05 0005 Ion movements and membranes in
cardiovascular control - Properties of isolated cell
membranes (rabbits, cats)
(contd)
•Excludes routine methodotogy OR covers only general projects whicli preclude
"Oriented significantly to above subject.
indexing at the specific level.
M Grant has subproiects descnbing specific research aspects-
See Appendix for investigator's name and grant number
MUS
POIHL-161 17-05 0007 Ion movements and membranes in
cardiovascular control - Ptiysiological and molecular
properties of ionophores (dogs, rabbits)
R01HL1615206 Electrophysiology of neonatal to adult
heart (cats, frogs, guinea pigs)
ROlHL-16240-05 The cardiac histamine receptor (rabbits
guinea pigs)
ROlHL-16320-05 Vasoactive peptides which stimulate
smooth muscles (rats, human)
P01HL-16607-05 0003 Calcium ion and control of
cardiovascular function ■ Calcium transport in
sarcoplasmic membranes (animals)
ROlHL-1665606 Left ventricular function in exercise
(dogs)
ROlHL-1671003 lilyocardlal subcellular localization of
calcium (dogs)
P60HL-17269-04 0022 National heart and blood vessel
research and demonstration center - Medicinal chemistry
(rabbit, dog, guinea pig)
P60HL1 7269-04 0023 National heart and blood vessel
research and demonstration center • Cardiovascular
pharmacology -Ischemia, shock and heart failure (dog cat
rat)
P60HL- 1726904 0024 National heart and blood vessel
research and demonstration center • Section of
experimental cardiovascular surgery -Core facility
ROlHL-17459-03 Myocardial ischemia (dogs)
ROIHL-17555-05 Distribution and metabolism of labeled
digitaloids (dogs, guinea pigs)
R01HL-17629-03 Developmental aspects of cardiovascular
function (human, cats, rabbits)
ROlHL-17631-05 Experimental congestive heart failure and
hypertrophy (cats)
R01HL17796-04 Importance of aminosugars in digitalis
activity (cats, rabbits)
ROlHL-1 7993-04 0007 Ventricular dynamics from
surgically inserted markers - Digitalis after coronary artery
surgery (human)
R01HL18260-04 Cyclic nucleotide metabolism in lung
tissue (cattle)
ROlHL-18280-03 Regulation of cardiac contractility and
metabolism (rats)
R01HL18517-03 Intrinsic innervation of the heart (dogs)
Role of Na, K-ATPase inhibition on
ROlHL-1859803
digitalis action
ROlHL-18711-03
chicks)
ROlHL-18933-03
ventricle (dog)
R01HL19133-03
Electrophysiology of heart cells (rats,
Energy output and efficiency of left
Cardiac actions of digitalis (dogs, cats)
Cardiac electrophysiology -Effects of ions
Mechanical properties of isolated
Developing heart -Biophysical aspects
Mechanism of the inotropic action of
Contractile and elastic properties of
cardiac muscle (cats)
ROlHL-1942303 Catecholamine action on the heart (cats,
rats)
ROlHL-19487-03
ROlHL-20558-02
and drugs
ROlHL-20613-02
myocardium
ROlHL-20749-01
(sheep)
" ROlHL-21014-01
cardiac glycosides
ROlHL-21182-02 Active tension and shortening in cardiac
hypertrophy (rabbits)
R23HL-21325-02 Sarcomere kinematics in cardiac
contraction (rats, rabbits)
ROlHL-2132902 Beta-receptor regulation and cardiac
sites of drug action (cat, guinea pig, rat)
R23HL 21409-02 Perinatal control of the ductus arteriosus
(sheep)
ROlHL-21457-01 C(17)-side group geometry and
cardenolide activity (cats, guinea pigs)
R01HL-21570-01 The mechanical basis of myocardial
energetics (cats)
ROlHL-22080-01 Phosphorus NMR studies on cardiac
tissue (rats, rabbits)
ROlHL-2213602 Histamine and cardiac adenyl cyclase
ROIHL-22231-02 Modulation of calcium control of cardiac
myofibrils (rats)
R01HL-22269-Q1 Excitation-contraction coupling in
enlarged hearts (rabbits)
R23HL-22309-0I Cardiovascular pharmacodynamics In
immature dogs
ROlHL-2256801 pH effect in heart cells -Influence of
cardiac drugs (tissue culture, rats)
R23HL-22575-01 Factors modifying cardiac digoxin effects
and content (dogs, cats)
P01HL-226I9 01 Cellular mechanisms of heart failure
■ POIHL 22619-01 0003 Cellular mechanisms of heart
failure - Digitalis induced inotropy in myocardial ischemia
heart failure (animals)
POlHL-226 19-01 0006 Cellular mechanisms of heart
failure - Phosphorylation of contractile proteins in cardiac
muscle contraction (dogs, rabb
ROlHL-2268501 Drugs and excitation-contraction coupling
in heart (animals)
ROlHL-22778-01 Total synthesis of natural cardiotonic
ionophores
ROlHL-23245-01 Adrenergic receptors in pulmonary
vascular muscle (human, animal)
ROIHL 23990-01 Role of phosphoprotein in cardiac
inotropic responses
360
MUSCLE STRESS
SEE MUSCLE FUNCTION, MUSCLE STRESS
MUSCLE STRETCH RECEPTORS
SEE MUSCLE FUNCTION, MUSCLE STRETCH (RECEPTORS)
MUSCLE STRETCH REFLEX
SEE MUSCLE FUNCTION, MUSCLE STRETCH REFLEX
MUSCLE TENSION
SEE MUSCLE FUNCTION, MUSCLE TENSION
MUSCLE TONE
SEE MUSCLE FUNCTION, MUSCLE TONE
MUSCLES
SEE ALSO HEART, MYOCARDIUM
SEE ALSO HEART, PAPILLARY MUSCLES
SEE ALSO RESPIRATORY MUSCLES
R01HL14785-07 Ultrasonic scattering for tissue
characterization (dogs, cattle, human)
" POlHL-15835-06 0027 Study of muscles related to heart
disease - Core II -Intermediate voltage EM of muscle
ROlHL-17080-05 Localization of pore systems in capillary
walls (rats, mice, rabbits)
ROlHL-18489-03 Hemodynamic Interactions of vasoactive
chemicals (rats)
ROlHL-19008-02 Carbon dioxide diffusion in lung and
muscle tissues (dogs)
POlHL-19737-02 0008 Cellular and molecular aspects of
respiratory physiology - Kinetics of movement of acid
metabolites from cell to capillary blood (dogs)
ROlHL-22406-01 Isobaric vascular bubbles and
decompression sickness (goats, models)
ROlHL-22506-01 ' Hemodynamics of the clinical
hypertensions
MUSCLES, MYOFIBRILS
ROlHL-03290-22 Controls of cardiac and vascular smooth
muscles (cats, rats, dogs)
ROlHL-05949-18 Biochemistry of muscle contraction (rats.
rabbits)
POIHL-0628518 0173 Cardiovascular-respiratory
physiology and biochemistry ■ Skeletal and cardiac muscle
function
POlHL-06285-18 0180 Cardiovascular-respiratory
physiology and biochemistry - Vagal C-fibers and their
influence on visceral and somatic function (animals)
ROlHL-0917215
muscle (rats)
R01HL-1001811
culture (rats)
ROlHL-10503-13
Protein and RNA synthesis in heart
Effect of aging on beating heart cells in
Cardiac ion transport and ultrastructure
(rats, guinea pigs, rabbits)
POIHL 11310-12 0085 Mechanisms of cardiovascular
disease ■ Mechanics of isolated cardiac muscle (animals)
POIHLI 1351-12 0003 Cellular and molecular
mechanisms of myocardial function - Mechanical and
electrical properties of cardiac muscle (rabbits)
POIHLI 1351-12 0006 Cellular and molecular
mechanisms of myocardial function - Molecular physiology
and energetics of muscle (frogs)
POIHLI 1351-12 0019 Cellular and molecular
mechanisms of myocardial function ■ Mechano-chemical
kinetics of small perturbations
R01HL-11551-1I RNA and protein synthesis in repair of
heart injury (mice, rats)
R01HL13454-08 Behavioral stress and cardiomyopathy
(monkeys, cats)
R01HL1383108 Factors regulating embryonic cardiac
morphogenesis (chick, salamandra)
POlHL-14388-07 0173 Regulation of the circulation in
pathological states - Mechanisms of cardiac myosin ATPase
ROlHL-15391-07 EPR studies on rotational motion of
myosin and actin
ROIHL- 156 79-06 Heart and smooth muscle contractile
protein (swine, cattle, rabbits, chickens)
ROlHL-15692-07 Force and speed in skeletal and cardiac
muscle
POlHL-15835-06 0002 Study of muscles related to heart
disease - Proteins of smooth muscle system (cattle,
rabbits)
POIHL- 158 3 5-06 0006 Study of muscles related to heart
disease - Ultrastructural and chemical studies of muscle
(animals)
POlHL-15835-06 0007 Study of muscles related to heart
disease - Structure and function of Limulus striated and
cardiac muscle
POlHL-15835-06 0009 Study of muscles related to heart
disease - Aspects of cardiac and skeletal myogenesis
(chick embryo)
POlHL-15835-06 0010 Study of muscles related to heart
disease - Muscle structure and reaction to injury (mice,
rats)
POlHL-15835-06 0019 Study of muscles related to heart
disease - Vascular smooth muscle -Electron microscopy,
excitation contraction (animal)
POIHL 15835-06 0025 Study of muscles related to heart
disease - Cellular biology of vascular smooth muscle
(guinea pig)
ROlHL-15888-05 Comparative stereology of the
myocardium (birds, mammals)
Contractile activation of skinned cardiac
Characterization of collateral blood
Cardiac fiber direction and the (3RS
•Excludes routine methodology OR covers only general projects which preclude indexing
Oriented significantly to above subject.
at the specific level.
M Grant has subprojects describing specific research aspects
See Appendix for investigator's name and grant number.
MUS
POlHL-1611705 0002 Ion movements and membranes in
cardiovascular control - Fluorescence and excitation-
contraction coupling in heart (frogs)
R01HL16606-11 Contraction in heart and other striated
muscles (frogs)
ROlHL-16637-04 Development and regression of cardiac
hypertrophy (rats)
POlHL-16683-04 0001 Function and growth of cardiac
and skeletal muscle - Light chains of the skeletal and
cardiac myosin molecule (rabbits, frogs)
" POIHL 16683-04 0003 Function and growth of cardiac
and skeletal muscle - Movements of S-1 moieties in muscle
fibers
R01HL-I7376-04 Analysis of Z bands in heart by optical
diffraction (mammals)
** P50HL-1764804 0025 Study of ischemic heart disease -
Destruction and repair of cardiac muscle cell constituents
(rat)
P50HL-1 7648-04 0026 Study of ischemic heart disease -
Control of muscle cell proliferation (organ culture)
P50HL1 7648-04 0031 Study of ischemic heart disease -
Ultrastructural consequences of myocardial ischemia (rat)
P50HL-17682-04 0024 Study of ischemic heart disease ■
Phosphorylation of cardiac contractile proteins during
ischemia (rat, guinea pig)
ROlHL-17998-04 Regulatory mechanisms in blood
circulation (dogs)
ROlHL-18032-03 Development of normal and myopathic
mammalian heart (hamsters)
ROlHL-18077-04 Smooth muscle cell organization and
Ca20 concentration control (chickens)
R01HL18087-03 Development and regression of cardiac
hypertrophy (rats, rabbits)
ROlHL-18145-03 Oxygen transport mechanisms in hypoxia
(dogs, rats, rabbits)
ROlHL-18612-03 Thin filament control of heart contraction
(cattle)
ROlHL-18631-03 Ultrastructural correlates of myocardial
ischemia (rats, swine)
POlHL-18708-03 0007 Oxygen, energy and contractility in
cardiac tissue - Surfaces, energy requirements, and
contractile proteins of cardiac cell in vitro
ROlHL-19138-03
cells (mammals)
ROlHL-19275-03
vessels (dogs)
* ROlHL-20273-02
complex (dogs)
POlHL-2059202 0001 Cell biology of cardiac and
skeletal muscle - Molecular mechanism of muscle
contraction (animals)
POlHL-2059202 0011 Cell biology of cardiac and
skeletal muscle - Myosin and cytochrome oxidase
messenger RNAs (chicken)
• POlHL-20592-02 0012 Cell biology of cardiac and
skeletal muscle ■ Contractile properties of skinned muscle
fibers (frogs)
' POlHL-20984-02 0004 Cellular mechanisms in cardiac
hypertrophy - Myofibril accumulation in cardiac and
vascular muscle cells in hypertrophy
R23HL-21325-02 Sarcomere kinematics in cardiac
contraction (rats, rabbits)
ROlHL-21493-02 Contractility in cardiac failure (hamsters)
ROlHL-21500-02 Performance of respiratory muscles under
stress (dogs)
ROlHL-21970-01 Myofibrillar assembly and breakdown in
cardiac muscle (rats)
ROlHL-21993-01 Hypertensive hypertrophy-Effects of
cardiac mechanics (rats)
ROlHL-22231-02
myofibrils (rats)
ROlHL-22290-01
synthesis (mice)
ROlHL-22538-01
rabbits)
ROlHL-22550-02
and hamsters
POlHL-22619-01 0005 Cellular mechanisms of heart
failure - Molecular mechanism of regulation of cardiac
muscle contraction (cattle)
POlHL-22619-01 0006 Cellular mechanisms of heart
failure - Phosphorylation of contractile proteins in cardiac
muscle contraction (dogs, rabb
POlHL-22619.01 0007 Cellular mechanisms of heart
failure - Regulation of contractile protein levels in heart
muscle (rats)
ROlHL-2265101 Control of protein metabolism in heart
muscle
ROlHL-23128-01 Cardiac contractility-Ischemia and
hypoxia (rabbits, rats)
ROlHL-2313801 Myocardial ischemia (dogs, rats, chick
embryo)
ROlHL-23161-01 0001 Biology of myocardial ischemia -
Mitochondrial lipid metabolism and cardiac ischemia (rat
dog)
ROlHL-23161-01 0004 Biology of myocardial ischemia ■
Structure of myofibrils and membranes in early ischemia
(dogs, rabbit, rodents)
ROlHL-23206-01 Repetitive exercise and cardiac
enlargement (dogs)
ROlHL-23233-01 Pulmonary artery intermediate filament
structure (cattle)
(contd)
Modulation of calcium control of cardiac
Cardiac energy metabolism and protein
Myosin as a multi-enzyme complex (dogs.
Genetic cardiomyopathies in salamanders
MUS
ROIHI 23614 02 Phitm»coloiy of lelaxstion m smooth
muscia (mollusks)
ROIHI 23990 01 Rol« ol phojphopiotein in oidiac
inotropic lesponsts
MUSCLES, MYOGENESIS
POIHL 0628b 18 0W9 Catdiovjsculai respiratory
pltysiolojy and biochemistry Rejulation ot myocardial cell
growth (lats, chick embryo)
ROIHL 09172 lb Protein and RNA synthesis in heart
muscle (rats)
ROIHL 10S03 13 Cardiac ion transport and ultrastructure
(rats, tuinea pigs, labbits)
P01HLI1310 12 0089 Mechanisms of cardiovascular
disease Structure and function in myocardial contraction
(dogs)
P01HL11351 12 0004 Cellular and molecular
mechanisms ot myocardial (unction Molecular
mechanisms of contiactile function and difterentiation
(animals)
POIHL 11351 12 0011 Cellular and molecular
mechanisms of myocardial (unction Comparative
contractile tissue studies (animals)
POIHL 1215711 0055 functions and mechanisms of cell
membrane ion transport Growth and development of
synthetic strand heart cells in culture (chick embryo)
•• POlHL-12373 10 0005 Cardiopulmonary physiology and
pathophysiology Characterization of fetal and neonatal
myocardium (human, cats)
•• R01HL13831-08 Factors regulating embryonic cardiac
morphogenesis (chick, salamandra)
•• P01HL1583506 0009 Study o( muscles related to heart
disease Aspects of cardiac and skeletal myogenesis
(chick embryo)
POIHL 15835 06 0010 Study of muscles related to heart
disease Muscle structure and reaction to injury (mice,
rats)
POlHL-1583506 0019 Study of muscles related to heart
disease ■ Vascular smooth muscle -Electron microscopy,
excitation contraction (animal)
POlHL-15835-06 0025 Study of muscles related to heart
disease - Cellular biology of vascular smooth muscle
(guinea pig)
*• R01HL18032-03 Development of normal and myopatt\ic
mammalian heart (hamsters)
P01HL1870803 0007 Oxygen, energy and contractility in
cardiac tissue ■ Surfaces, energy requirements, and
contractile proteins of cardiac cell m vitro
POlHL-20592-02 0011 Cell biology of cardiac and
skeletal muscle - Myosin and cytochrome oxidase
messenger RNAs (chicken)
** ROlHL-22550-02 Genetic cardiomyopathies in salamanders
and hamsters
** ROlHL-22859-01 Effect of carbon monoxide on the
developing heart (rats)
** R23HL-2295901 Heart development in inherited
cardiomyopathy (hamsters)
*♦ ROlHL-23013-01 Smooth muscle development in vitro
(chick embryo)
ROlHL-23232-01 Effect of hypoxia on PVSM and its
precursor cells
MUSCLES, SARCOLEMMA
POlHL-06308-18 0025 Mechanisms and therapy ot
circulatory disease - Subcellular calcium pools in the
genesis of arrhythmias (dogs)
ROlHL-09234-13 Amino acids of contractile proteins ot
failing hearts (dogs, hamsters)
R01HL10503-13 Cardiac ion transport and ultrastructure
(rats, guinea pigs, rabbits)
POlHL-11351-12 0001 Cellular and molecular
mechanisms of myocardial function ■ Ionic control of
myocardial contractility (animals)
ROlHL-12774-08 Ionic coupling in activation of cardiac
muscle (frogs, guinea pigs)
ROlHL-15498-06 Effects of physical training on heart
(rats)
POlHL-15835-06 0021 Study of muscles related to heart
disease - Fast kinetic studies in muscle subcellular
organelles (animals)
** POlHL-16117-05 0005 Ion movements and membranes in
cardiovascular control - Properties of isolated cell
membranes (rabbits, cats)
P50HL-1767004 0023 Study of ischemic heart disease ■
Energy metabolism in acute myocardial ischemic injury
(dogs)
ROlHL-17702-04 Electro-optical dyes as probes of heart
excitability
ROlHL-18032-03 Development of normal and myopathic
mammalian heart (hamsters)
ROlHL-18070-04 Regulation of intrapulmonary airways
and vessels (human, animals)
ROlHL-18629-04 Influence of aging and hypertension on
the myocardium (rats)
R0IHL18711-03 Eledrophysiology of heart cells (rats.
chicks)
ROlHL-18824-03 Mechanisms of heart failure in
myopathic hamster
ROlHL-19138-03 Contractile activation of skinned cardiac
cells (mammals)
ROlHL-19139-03 Dispersion of diffusible indicators in the
body (human, cats, dogs)
361
ROIHL 19148 03 Myocardial organelle lipid structure and
function (dog. rat)
ROIHL 21371 02 Energy loss microanalysis ot myocardial
cations
ROIHL 21493 02 Contractility in cardiac failure (hamsters)
R23HL 21 783 01 Ionic control of conttactility in anoxic
myocardium (rabbits, rats)
ROIHL 21812 02 Actions of drugs and ions on cardiac
membranes (rabbits, guinea pigs)
R23HL 22490 01 Neurotransmitter receptors of cultured
heart cells
ROIHL 2268501 Drugs and excitation contraction coupling
in heart (animals)
ROIHL 2281301 Palmitylcarnitine inhibition of ion pumps
in ischemia (dogs)
R01HL2301301 Smooth muscle development in vitro
(chick embryo)
R01HL2312801 Cardiac contractility Ischemia and
hypoxia (rabbits, rats)
ROIHL 2313801 Myocardial ischemia (dogs, rats, chick
embryo)
R01HL23142-01 Mechanisms of membrane in)ury in
myocardial ischemia (dog)
ROIHL 23161 01 0001 Biology of myocardial ischemia
Mitochondrial lipid metabolism and cardiac ischemia (rat.
dog)
ROlHL-23161 01 0002 Biology of myocardial ischemia
Palmitylcarnitine inhibition of ion pumps in myocardial
ischemia (dog. sheep)
MUSCLES, SMOOTH MUSCLE
SEE ALSO MUSCLE CELLS. MYOEPITHELIAL CELLS
SEE ALSO SLOW REACTING SUBSTANCES
ROlHL-01803-23 0017 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Contractile and relaxing proteins of blood
vessels and platelets (mammals, human)
ROlHL-01803-23 0020 Arteriosclerosis, glomerulonephritis.
rheumatic fever Virus-induced arterosclerosis (chickens)
POlHL-03174-23 0001 Mechanisms of acute vascular
reaction to injury - Response of the vascular intima to
injury (human, rats)
** ROlHL-03290-22 Controls of cardiac and vascular smooth
muscles (cats. rats, dogs)
ROlHL-05883-18 0001 Reflex control of resistance and
capacitance vessels - Naturally occurring vasoactive
substances and the vascular neuroetfectors (dog)
ROlHL-05883-18 0002 Reflex control of resistance and
capacitance vessels - Adenosine, adenine nucleotides and
vascular smooth muscle (dog)
ROlHL-05883-18 0003 Reflex control of resistance and
capacitance vessels - Cardiac glycosides and sympathetic
nerve terminals in vascular smooth muscle
POlHL-06285-18 0136 Cardiovascular-respiratory
physiology and biochemistry - Fetal microcirculation in
utero (rabbits, lambs)
POlHL-06285-18 0188 Cardiovascular-respiratory
physiology and biochemistry - Physiology and pharmacology
in regulation of airways-hyperirritability (animals)
POlHL-0631417 0053 Immunologic mechanisms in
cardiovascular disease - Cellular functions controlled by
cyclic GMP (human, mice, guinea pigs)
POlHL-0631417 0054 Immunologic mechanisms in
cardiovascular disease - Physiology of cell communications
(mice, frogs, guinea pigs)
POlHL-06835-17 0055 Cardiovascular disease - Vascular
and adrenocortical response to angiotensin II (dogs)
P01HL06835-17 0056 Cardiovascular disease -
Angiotensin analogs-Sarcosine on arterial pressure,
aldosterone (dogs)
R01HL-07723-I5 Reflex control of vascular capacitance in
shock
ROlHL-0835914 Morphopharmacology of vascular
adrenergic transmission (rabbits, rats)
** POlHL-08682-15 0005 Regulation of the cardiovascular
system - Smooth muscle and mechanical properties of
blood vessels (dogs, human)
POlHL-08899-14 0040 Tolerance to respiratory gases in
health and disease Metabolic gas influence on brain
vascular tissue (animals)
ROlHL-09544-12 Biochemistry of contractile proteins
(animals)
POlHL-11351-12 0011 Cellular and molecular
mechanisms of myocardial function • Comparative
contractile tissue studies (animals)
POlHL-1 14 14-11 0037 Thrombosis and atherosclerosis
program - Vascular intimal injury and healing (rabbits,
rats)
R01HL-12766-09 Structure-function relation of blood
vessels (rats, monkeys)
R01HL12792-09 Local control of the microcirculation
(hamsters, rats)
ROlHL-12869-09 Arterial metabolism, diabetes and
atherogenesis (rats, rabbits)
POlHL-13262-07 0012 Arterial wall in atherosclerosis -
Characterization of connective tissue components (animals)
POlHL-13262-07 0023 Arterial wall in atherosclerosis -
Isolation and characterization of soluble elastin
POlHL-13330-08 0056 Mechanical circulatory support -
Blood compatibility linings (calves)
ROlHL-13909-27 Physiochemistry and immunology of
macromolecules
MUS
PbOHl 14138 05 OOl'j tciilei loi iciejith on
atherosclerosis Arterial wall Intermediary mdabolitm.
en/ymc activity and bioenergetics
P50III 1414/08 0012 Specitli/cd tenter ot research in
thrombosis Tissue culture study of arterial cell* (human,
hamster)
P50HI 14153 07 0013 Johns Hopkins Lung Canter
Chronic diseases of airways Pulmonary mechanics and
mediators of allergic reactions (guinea pigs, human)
P50HL 14164 0/ 0035 A/S SCOR Comparative and
experimental atherosclerosis Lipid metabolism Interaction
with arterial metabolism (monkey, pigeon)
P50HL 14164 07 0036 A/S SCOR Comparative and
experimental atherosclerosis Connective tissue
metabolism Interaction with arterial metabolism (monkeys)
■ P50HL 14217 08 0061 Specialized center of research in
thrombosis Pharmacology Comparison of platelets and
vascular smooth muscle (animal)
P50HL 14230 07 0095 A/S SCOR Lipids, atherosclerosis
and thrombosis Blood platelet adherence to endothelial
smooth muscle cells, fibroblast (human)
P50HL 14230 07 9002 A/S SCOR Lipids, atherosclerosis
and thrombosis Core tissue culture laboratory
P50HL 14237 07 0002 Support lor arteriosclerosis center
■ Interactions of lipoprotein particles with vascular surface
(human, rat)
Regulation of the circulation in
Subcellular distribution of calcium
POIHL 1438807 0153
pathological states
(rats)
POlHL-1438807 0154
pathological states
contraction (rats)
POIHL 14388-07 0158
pathological states
Regulation of the circulation in
Energetics of smooth muscle
Regulation of the circulation in
Developmental aspect of abnormal
vascular reactivity (rats)
POIHL 1438807 0167 Regulation of the circulation in
pathological states Increased reactivity of artery vascular
muscle in spontaneously hypertensive rat
POlHL-14388-07 0168 Regulation of the circulation in
pathological states Ionic basis of depolarization (rats,
tissue culture)
POlHL-14388-07 0172 Regulation of the circulation in
pathological states cAMP-dependent protein kinase from
heart and vascular smooth muscle (guinea pigs)
POlHL-14388-07 0178 Regulation of the circulation in
pathological states - Structural and functional
consequences of denervation (rats)
POlHL-14388-07 0179 Regulation of the circulation in
pathological states - Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
POlHL-14388-07 0185 Regulation of the circulation in
pathological states - Reflex control of venous tone (human,
rabbits, dogs)
POlHL-14388-07 0198 Regulation of the circulation in
pathological states Humoral factors in vascular reactivity
in spontaneously hypertensive rats
POlHL-14388-07 0199 Regulation of the circulation in
pathological states - Adrenergic stimulation in
spontaneously hypertensive rats
POlHL-14388-07 0229 Regulation of the circulation in
pathological states - Mechanism of postural hypotension
(human)
' ROlHL-14523-07 Generation and regulation of force in
smooth muscle (animals)
POlHL-14580-07 0001 Program project in respiratory
mechanics - Micromechanics of the lung (dogs, rats)
' ROlHL-14775-08 Mechanisms of drug action in vascular
smooth muscle (dog. rabbits)
* POlHL-14985-07 0012 Adaptation to hypoxia - Direct
effect of hypoxia on pulmonary vascular smooth muscle
(rats, dogs)
* P50HL-15061-07 0005 Response of lung to injury - Airway
smooth muscle in health and disease (dogs, guinea pigs)
P50HL-15062-07 0001 Study of lipoproteins, artery wall,
and atherosclerosis Structure and molecular interactions
of serum lipoproteins (human, monkey)
* P50HL-15062-07 0012 Study of lipoproteins, artery wall.
and atherosclerosis - Lipoprotein stimulation of arterial
smooth muscle cell proliferation (mammals)
* P50HL-15062-07 0019 Study of lipoproteins, artery wall,
and atherosclerosis - Factors regulating lipoprotein-smooth
muscle cell interaction (monkey)
P50HL-15062-07 0020 Study of lipoproteins, artery wall.
and atherosclerosis - Artery wall reactions-Elevated
pressure and hyperlipemia (monkey)
ROlHL-15391-07 EPR studies on rotational motion of
myosin and actin
ROlHL-15522-06 Influence of mannitol on ischemia
cardiac muscle (dogs, cats, rats)
ROlHL-15580-06 Humoral control of pulmonary and
systemic circulation (animals)
" ROlHL-15646-03 Lipid studies in vascular smooth muscle
cells (human, monkeys)
ROlHL-15679-06 Heart and smooth muscle contractile
protein (swine, cattle, rabbits, chickens)
R01HL-1580506 Cerebral arterial tone and reactivity
(rabbits)
POlHL-1583506 0001 Study of muscles related to heart
disease - Control ot contraction-relaxation of heart and
muscle (rabbits, chickens)
(contd)
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
•'Onented significantly to above subject.
M Grant has subprojecls describing specific research aspects.
See Appendix for investigator's name and grant number.
MUS
" POIHLI 5835-06 0002 Study of muscles related to heart
disease ■ Proteins of smooth muscle system (cattle
rabbits)
P01HL15835-06 0006 Study of muscles related to heart
disease - Ultrastructural and chemical studies of muscle
(animals)
POlHL-1583506 0009 Study of muscles related to heart
disease - Aspects of cardiac and skeletal myogenesis
(chick embryo)
P01HL15835-06 0010 Study of muscles related to heart
disease - Muscle structure and reaction to injury (mice
rats)
POlHL-15835-06 0011 Study of muscles related to heart
disease Energetics and mechanism of muscle contraction
(frogs, rabbits)
** POlHL-1583506 0012 Study of muscles related to heart
disease ■ Contraction and energetics of visceral and
vascular smooth muscles (rabbits)
POIHL- 1583 5-06 0018 Study of muscles related to heart
disease - Pharmacology of excitation coupling in muscle
(frog, barnacles)
" POlHL-15835-06 0019 Study of muscles related to heart
disease - Vascular smooth muscle-Electron microscopy,
excitation contraction (animal)
P01HL15835-06 0021 Study of muscles related to heart
disease - Fast kinetic studies in muscle subcellular
organelles (animals)
" POlHL-15835-06 0025 Study of muscles related to heart
disease - Cellular biology of vascular smooth muscle
(guinea pig)
P01HL1583506 0027 Study of muscles related to heart
disease Core II- Intermediate voltage EM of muscle
ROlHL-1585206 Vascular ion transport and hypertensive
mechanisms
R0IHL16003-08 Sources and roles of calcium in smooth
muscle excitation (rats)
P01HL161 17-05 0001 Ion movements and membranes in
cardiovascular control Developmental studies of
contractile cell junctions (rats, rabbits, elasmobranch)
P01HL-16I17-05 0006 Ion movements and membranes in
cardiovascular control - Neuroreceptors and cellular
excitation (fish)
P01HL16117-05 0008 ion movements and membranes in
cardiovascular control Arterial smooth muscle calcium
fluxes and contractility (rabbits)
ROlHL-16320-05 Vasoactive peptides which stimulate
smooth muscles (rats, human)
ROlHL-16328-06 Membrane electrical properties of
vascular muscle (human, animals)
POlHL-1638704 0003 The blood vessel and
thrombogenesis - Blood vessel healing (rabbits)
POlHL-1638704 0004 The blood vessel and
thrombogenesis Analysis of vascular basement membrane
by enzymatic methods (human)
■* POlHL-16387-04 0009 The blood vessel and
thrombogenesis Role of pituitary gland in the
pathogenesis of arteriosclerotic lesions (rats)
•* ROlHL-1645403 Vascular muscle reactivity in
hypertension (human, rats)
POlHL-16607-05 0007 Calcium ion and control of
cardiovascular function - Ultrastructure and conformation
in sarcoplasmic reticulum (rabbits)
R01HL16714-05 Endothelial cell communication in
homeostasis (human, mammals)
ROlHL-16904-03 Regulation of smooth muscle cells in
arteriosclerosis (rabbit aorta)
POlHL-16910-05 0001 Regulation of the peripheral
circulation - Quantitative studies of microcirculatory control
(bats)
ROlHL-1732204 Functional characteristics of smooth
muscle isolated from lung (animals)
ROlHL-17335-05 Contractile properties of hypertensive
arterioles (rats)
* POlHL-1742105 0002 Regulation and exchange in the
microcirculation - Metabolic and myogenic blood flow
regulation in microcirculation (animals)
POIHL- 1742 1-05 0003 Regulation and exchange in the
microcirculation - Transcapillary fluid exchange in rat
intestinal muscle, mucosa, and mesentery
POlHL-17421-05 0004 Regulation and exchange in the
microcirculation Localization of flow regulation in the
microcirculation (cats, human)
ROlHL-1757604 Role of sphingomyelin in biomembranes
and bilayers (rats, other mammals)
ROIHL 17747-04 Endothelial injury and regeneration (rats)
ROIHL-1 7783-04 Complex carbohydrates Structure,
function, synthesis (swine)
POlHL-17871-04 0010 Kidney, sodium, cardiac output,
arterioles and hypertension ■ Renal prostaglandins
metabolism in hypertension (rats, dogs)
ROlHL-18015-03 Pharmacologic studies on vascular
smooth muscle (dogs, rats)
R01HL18070-04 Regulation of intrapulmonary airways
and vessels (human, animals)
ROlHL-18077-04 Smooth muscle cell organization and
Ca20 concentration control (chickens)
ROIHL 18259-03 Controlled intratissue release of
prostaglandins
ROlHL-18260-04 Cyclic nucleotide metabolism in lung
tissue (cattle)
Regulation of neurotransmitter release by
Organization of arterial ground substance
Biology of the artery wall and
362
P50HL-183 18-03 0015 Pathogenesis and complications of
hypertension ■ Cultured smooth muscle cells and
microvessel metabolism (mammals)
R01HL18473-04 Genesis of atherosclerotic lesions
(human, mules)
ROIHL 18516-03 Atherosclerosis and the arterial
contractile proteins (pigs, rabbits)
M POlHL-18575-03 Mechanisms of vascular changes in
hypertension
P01HL18575-03 0001 Mechanisms of vascular changes
in hypertension - Arteries and resistance vessels in
hypertension (pigs, rats)
POlHL-1857503 0007 Mechanisms of vascular changes
in hypertension - Microscopy of hypertensive arterial lesions
(rats)
ROlHL-1860101
adenosine (rats)
ROlHL-18625-03
(cattle)
M POlHL-1864503
atherosclerosis
" POlHL-18645-03 0001 Biology of the artery wall and
atherosclerosis - Primate arterial smooth muscle and
atherosclerosis
" P01HL18645-03 0003 Biology of the artery wall and
atherosclerosis Synthesis of connective tissue proteins by
smooth muscle cells (human, monkeys)
** P01HL18645-03 0004 Biology of the artery wall and
atherosclerosis ■ Human arterial smooth muscle cell and
lipoprotein interaction
POlHL-18645-03 0005 Biology of the artery wall and
atherosclerosis - Effects of atherosclerosis risk factors on
endothelium of the primate
POlHL-18645-03 0006 Biology of the artery wall and
atherosclerosis ■ The platelet and atherosclerosis (monkeys,
baboons)
POIHL 1870803 0008 Oxygen, energy and contractility in
cardiac tissue - Cardiac cell culture facility
ROlHL-1871404 Cardiovascular matrix-Morphogenesis
and maturation (human, chick embryo, mammal)
ROIHL 18826-04 Interaction of peptides and target cells
in lung (human)
ROlHL-18831-03 Microscopy of spontaneously hypertensive
arterial lesion (rats)
R01HL19008-02 Carbon dioxide diffusion in lung and
muscle tissues (dogs)
ROlHL-1901103 Smooth muscle cell membrane
glycoprotein biosynthesis (cattle)
ROlHL-1901203 Smooth muscle of resistance vessels in
hypertension (rats)
ROIHL 1902703 Calcium and cyclic AMP in causation of
hypertension (rats)
ROlHL-19066-03 Synthesis and evaluation of
prostaglandin metabolites (guinea pigs)
R01HL19082-01 Hypoxia-induced relaxation of vascular
smooth muscle
R01HL-I91 15-02 Hormonal control of tracheobronchial
cyclic AMP (rats, guinea pigs)
P50HL-19156-02 0005 Pulmonary SCOR-Chronic diseases
of airways - Vagal receptors in the airway-Epithelial injury
and antigen (dog, cat, rabbit)
P50HL-191 70-02 0003 Harvard pulmonary SCOR-Chronic
diseases of the airways - Mechanisms of bronchial
reactivity to acute and chronic airway challenge (dog)
R01HL19202-03 Adenosine, prostaglandins in relation to
coronary flow (guinea pigs)
R01HL19226-03 Vascular smooth muscle in hypertension
(rats)
« POlHL-19242-02 Study of vascular smooth muscle
" POlHL-19242-02 0001 Study of vascular smooth muscle -
Energy metabolism and protein turnover in vascular smooth
muscle (rats)
'* POlHL-19242-02 0002 Study of vascular smooth muscle -
Vascular smooth muscle response to serum lipoproteins
(rats)
* P01HL19242-02 0003 Study of vascular smooth muscle -
Vasoactive metabolites from vascular muscle and
parenchymal tissue (animal)
* POlHL-19242-02 0004 Study of vascular smooth muscle -
Cyclic nucleotide metabolism in smooth muscle cultures
(human, rats)
* POIHL-19242-02 0006 Study of vascular smooth muscle -
The contractile system of vascular smooth muscle (swine,
rats)
* POlHL-19242-02 0007 Study of vascular smooth muscle -
NE release in and reactivity of vascular smooth muscle
(animals)
* P01HL19242-02 0008 Study of vascular smooth muscle -
NE release in and reactivity of vascular smooth muscle
(rats)
* POlHL-19242-02 0009 Study of vascular smooth muscle -
Electrophysiology of vascular smooth muscle (rats, chick
embryo)
R01HL19275-03 Characterization of collateral blood
vessels (dogs)
ROlHL-19299-03 Myoglobin and oxygen supply to heart
and muscle cells (rats, pigeons)
ROIHL 19653-03 Circulatory system effects of angiotensin
analogs (rats)
R01HL19677-03 Venous structure and function (dogs)
MUS
P01HL19717-02 0007 Response of the lung to injury ■
Cellular level studies of prostaglandinlike molecules
(cattle)
'* P01HL19737-02 0002 Cellular and molecular aspects of
respiratory physiology - Airway smooth muscle in health
and disease (human, animals)
POlHL-19737-02 0009 Cellular and molecular aspects of
respiratory physiology Regulation of tissue oxygen tension
and body carbon monoxide stores (human, dogs)
* ROlHL-2005402 Cultured blood vessel cells--
Pathophysiology (human, animals)
ROlHL-2008702 Developmental processes in pulmonary
hypertension (rats)
ROlHL-2012202 Operational mechanisms of airway
receptors (dogs, pigs)
ROlHL-2018402 Desensitization of tracheal muscle to
isoproterenol (rats, rabbits)
ROlHL-20196-02 Regulation of coronary arterial smooth
muscle
ROlHL-20339-02 Vascular alphaadrenergic receptor
molecular properties
ROIHL 20400-03 Diabetic neuropathy and peripheral
vascular diseases (human, hamsters)
ROlHL-20429-03 Study of effects of diabetes reactivity
(miniature pigs, rats)
ROlHL-2043902 Effects of insulin on neurovascular
transmission (human, rats, rabbits, hamsters)
ROlHL-20542 03 Regional hemodynamics in spontaneous
hypertension (rats)
ROlHL-2056302 Restoring microcirculation after platelet
aggregation
POlHL-20581-01 Vascular neuroeffector mechanisms in
health and disease
■ P01HL2058101 0001 Vascular neuroeffector
mechanisms in health and disease - Vascular neuroeffector
mechanism (rabbits)
' POlHL-20581-01 0002 Vascular neuroeffector
mechanisms in health and disease - Trophic interaction
between adrenergic nerves and vascular smooth muscle
POlHL-20581-01 0003 Vascular neuroeffector
mechanisms in health and disease - Cerebrovascular
neuroeffector characteristics (animals)
■ POlHL-20581-01 0004 Vascular neuroeffector
mechanisms in health and disease - Neuroeffector
characteristics of mesenteric and pulmonary blood vessels
(rabbits)
POlHL-20581-01 0005 Vascular neuroeffector
mechanisms in health and disease ■ Changes in the
neuroeffector mechanism in hypertension (rabbits)
POlHL-2058101 0006 Vascular neuroeffector
mechanisms in health and disease - Neuroeffector
mechanism in arteries and veins in hypertension (human)
POlHL-20592-02 0001 Cell biology of cardiac and
skeletal muscle - Molecular mechanism of muscle
contraction (animals)
ROlHL-20611-02
nucleotides
ROlHL-20782-01
(rats, dogs)
ROlHL-20783-02
Airway smooth muscle and cyclic
Coronary flow regulation by adenosine
•Excludes routine methodology OR covers only general projects which preclude indexine
Oriented significantly lo above subject.
at the specific level.
M Grant has subprojects describing specific research aspects
See Appendix for investigator's name and grant number.
Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
ROlHL-2078702 Thromboxanes and prostaglandins-
Biochemical pharmacology (rabbits, human)
ROlHL-20924-02 Atherosclerosis and arterial cell functions
(human, rabbits)
* POlHL-20948-02 0002 Molecular basis of cholesterol
metabolism • LOL pathway in cell lines with informative
properties other than fibroblasts
I POIHL 2099302 Population dynamics of arterial cells in
atherogenesis
* POlHL-2099302 0001 Population dynamics of arterial
cells in atherogenesis - Arterial SMC population dynamics
in atherogenesis (swine)
POlHL-2099302 0007 Population dynamics of arterial
cells in atherogenesis - Interaction of lipoproteins in
hypercholesteremia (human, swine)
POlHL-2099302 0008 Population dynamics of arterial
cells in atherogenesis - Angiotoxicity of cholesterol
oxidation in atherogenesis (rabbits)
■ P50HL-21006-02 0004 Specialized center of research in
arteriosclerosis - Regulation of growth of human arterial
smooth muscle cells by platelets
ROlHL-21030-Ot Calcium regulation and hypertension
(rats)
ROlHL-2 11 03-01 Parametric mechanical studies of
hypertensive arteries (dogs, rats)
ROlHL-21 187-01 Potassium, norepinephrine, and coronary
arterial tone (dogs)
R23HL-212I3-01 A model for calcium homeostasis in
excitable tissue (marine worms)
ROlHL-2123902 Isolation and mechanism of action of
thromboxane A2 (human, rabbits)
ROlHL-21303-02
vascular cells
R23HL 21462-02
arteries (dogs)
R23HL-21488-01 Myosin-linked regulation in vertebrate
smooth muscle (calf aorta)
ROlHL-21498-02 Pathophysiology of edema (rats, cats)
R23HL-21 53902 Mechanical properties of isolated small
bronchioles (rabbits)
(contd)
Collagen synthesis by cultured human
Mechanical interactions between ventricle
MUS
POIHI 21S84 02 0005 Respualoiy mechanics <n noim«l
and abnormal stales Reiulation and behavior ol airway
smooth muscle (human, animals)
POIHL 21b8402 0006 Respiratory mechanics in normal
and abnormal states Respiratory mechanics in health and
disease (human, pigs)
R01HL2167301 Pathophysiology ol venous changes in
hypertension (rats, rabbits, human, dogs)
ROIHL 21756 11 Vascular disease Cytochemistry and
ultrastruclure (human, rats. mice, hamsters)
ROIHL 21851 01 Cerebral microcirculation in experimental
hypertension (cats, rabbits)
R23HL 21914 01 Studies ol vasomotor control (rats)
ROIHL 22053 02 The disordered lipid metabolism ol
diabetes mellitus (chickens, mammals, human)
ROIH12217702 Mechanisms ot control ol pulmonary
smooth muscle (dogs)
ROIHL 22194 02 Allosteric tunction ol platelet contractile
proteins (human)
' ROlHl-22216 02 Vascular mechanisms in renal
hypertension (dogs)
ROIHL 2222301 The cardio pulmonary junction (dogs,
models)
' ROIHL 2226401 Regulation ol contraction in vascular
smooth muscle (dogs)
' ROlHL-2248601 Enzyme regulation in cultured arterial
cells (swine)
ROIHL 2252701 Prostacyclin-thromboxanes in the
cardiovascular system (human, rabbits)
ROIHL 2256601 Mesoionic purinones as
phosphodiesterase inhibitors
POlHL-22602-01 0001 Pathophysiology ol the
endothelium Platelet-cndothelial interactions in vitro
(human, cattle)
* POlHL-22602 01 0004 Pathophysiology ol the
endothelium Endothelium, platelets smooth muscle and
atherosclerosis (rabbits)
* POlHL-2261901 0008 Cellular mechanisms ol heart
tailure - Molecular mechanisms and difterential contractile
responsiveness in VSM (dogs)
* POlHL-22619-01 0009 Cellular mechanisms ol heart
lailure Sarcoplasmic reticulum in cardiac, skeletal and
smooth muscle (rabbits, dogs)
* POlHL-2261901 0010 Cellular mechanisms ol heart
lailure - Mitochondria in heart and smooth muscle (rabbits.
rats, dogs)
ROlHL-22623-01 Polyamines cellular mediators ol
atherogenesis (human)
POlHL-2263301 0002 Cellular and molecular biology ol
lipoprotein metabolism - Sterol metabolism in tissue
culture cells
ROlHL-2273901 Evolution and progression ol pediatric
atherosclerosis
R23HL-22745-01 Vascular mechanics and structure in
hypertension (miniature swine)
ROlHL-22783-01 Hemodynamic induction of intimal
fibromuscular lesion
'* ROlHL-22784-01 Ductus arteriosus closure-An arterial
lesion model (rabbits)
R23HL-22972-01 Microcirculatory function in hypotension
Angiotensin II receptors -Mechanisms of
Smooth muscle development in vitro
Effect of hypoxia on PVSM and its
Pulmonary artery intermediate filament
(rats, hamsters)
•* ROlHL-22990-01
regulation (rats)
" ROlHL-23013-01
(chick embryo)
** RO1HL-23205-01 Contraction of pulmonary vascular
smooth muscle (cat)
" R01HL-23209-01 Autonomic receptors ol the pulmonary
vasculature (mammals)
** ROlHL-23210-01 Biology of normal and hypertrophied
pulmonary vessels (cat. human)
** ROlHL-23224-01 Hypoxia and pulmonary vascular smooth
muscle (rat. cat)
*• ROlHL-23232-01
precursor cells
*• ROlHL-23233-01
structure (cattle)
** ROlHL-23239-01 Functional characteristics of pulmonary
vascular smooth muscle (dogs)
** R01HL-23240-01 Pulmonary vascular muscle metabolism
and contractility (rats, cattle)
** ROlHL-2324501 Adrenergic receptors in pulmonary
vascular muscle (human, animal)
** ROlHL-23249-01 Actinmyosin interaction in pulmonary
smooth muscle (cattle)
** ROlHL-23542-01 Pulmonary vascular smooth muscle cell
dynamics (rat. rabbit)
ROlHL-23586-06 Pharmacologic control of hypersensitivity
phenomena (human)
ROlHL-2361402 Pharmacology of relaxation in smooth
muscle (mollusks)
ROlHL-23615-01 Biochemistry of contractile proteins
(chicken, rabbit)
MUSCLES, STRIATED MUSCLE
** R01HL-00082-30 Transmembrane movements (barnacles.
frogs, rats)
ROlHL-02953-17 Autonomic and cardiovascular
pharmacology (rats, rabbits, dogs, guinea pigs)
** POlHL-03174-23 0007 Mechanisms of acute vascular
reaction to injury ■ Healing of injured myocardium-Basal
lamina scaffold (human, rats, dogs)
363
ROIHI 03290 22 Controls ol cardiac and vascular smooth
muscles (cats. rats, dogs)
ROIHI 05883 18 000/ Rollei control ol resistance and
capacitance vessels Prostaglandins and skeletal muscle
blood How (dogs)
ROIHL 05949 18 Biochemislry ol muscle contraction (rats.
rabbits)
POIHL 06285 18 0173 Cardiovascular respiratory
physiology and biochemistry Skeletal and cardiac muscle
lunction
POIHL 06312 17 0034 Surgical cardiology Metabolic
lactors in cardiac lunction Creatine phosphate depletion
(animals)
ROIHL 06/36 18 Biogenic mechanical lactors in
microcirculation (rats, gerbils)
R01HL0772315
shock
Reflex control ol vascular capacitance in
Biochemistry ol contractile proteins
Blood How and nucleotide metabolism
ROlHL-0954412
(animals)
ROlHL-10384 13
(animals)
ROIHL 10881 13 Structure and function ot
microcirculation (hamsters, rats. cats, dogs)
P01HL1135112 0001 Cellular and molecular
mechanisms ol myocardial lunction - Ionic control ol
myocardial contractility (animals)
POIHL 11351 12 0006 Cellular and molecular
mechanisms of myocardial function Molecular physiology
and energetics of muscle (frogs)
POIHL 11351-12 0009 Cellular and molecular
mechanisms of myocardial function • Myocardial membrane
surface coat (rats, rabbits)
POIHL 11351 12 0011 Cellular and molecular
mechanisms of myocardial function Comparative
contractile tissue studies (animals)
POlHL-11351-12 0021 Cellular and molecular
mechanisms of myocardial function - Muscle energetics
(frogs)
ROlHL-1155111 RNA and protein synthesis in repair of
heart injury (mice, rats)
' ROlHL-1218609 Calcium transients in striated muscle
and other cells (mammals, frogs)
POlHL-1237310 0012 Cardiopulmonary physiology and
pathophysiology ■ Biochemistry of the sympathetic nervous
system (rats, rabbits, pigeons)
ROlHL-12493-10 Bioengineering analysis of microvascular
function (cats, rabbits)
ROIHL 12614-09 Microcirculatory control mechanisms and
hypertension (bats, rats)
ROIHL 12690-09 Systemic and local vascular adjustment
in shock (monkeys, cats)
* POlHL-12738-10 0098 Physiologic pharmacology and its
clinical applications - Skeletal muscle support of the
chronically failing heart (dogs)
* POlHL-12738-10 0109 Physiologic pharmacology and its
clinical applications Effects of calcium blockers on
skeletal and cardiac muscle (cats)
R01HL12974-10 Tracer kinetics, flows and masses in
body organs (human, dogs)
ROlHL-13694-08 Capillary basement membrane in
cardiovascular disease (human, rats)
ROlHL-14102-07 Human physiology at 5360 meters-
Mountain environment
ROlHL-14938-06
(dogs, rabbits)
ROlHL-15390-12
microcirculation
ROlHL-15391-07
myosin and actin
ROlHL-15562-05
(dogs)
ROlHL-15679-06
Contractile proteins of heart muscle
Regulation of blood flow in the
EPR studies on rotational motion of
Regulation of skeletal muscle blood flow
Heart and smooth muscle contractile
protein (swine, cattle, rabbits, chickens)
POlHL-15835 06 000! Study of muscles related to heart
disease - Control of contraction-relaxation of heart and
muscle (rabbits, chickens)
P01HL15835-06 0006 Study of muscles related to heart
disease - Ultrastructural and chemical studies of muscle
(animals)
** POlHL-15835-06 0007 Study of muscles related to heart
disease - Structure and tunction of Limulus striated and
cardiac muscle
** POlHL-15835-06 0009 Study of muscles related to heart
disease - Aspects of cardiac and skeletal myogenesis
(chick embryo)
** POIHL- 158 3 5-06 0010 Study of muscles related to heart
disease • Muscle structure and reaction to injury (mice,
rats)
POIHL- 158 3 5-06 0011 Study of muscles related to heart
disease - Energetics and mechanism ol muscle contraction
(frogs, rabbits)
** POlHL-15835-06 0018 Study of muscles related to heart
disease • Pharmacology of excitation coupling in muscle
(frog, barnacles)
POlHL-1583506 0021 Study of muscles related to heart
disease - Fast kinetic studies in muscle subcellular
organelles (animals)
POlHL-1583506 0023 Study of muscles related to heart
disease Cellular basis of the Frank-Starling curve (frogs,
rats)
POlHL-15835-06 0027 Study of muscles related to heart
disease • Core ll~lntermediate voltage EM ol muscle
MUS
ROIHI IbOlO 16 Cellular bam ol cardiac contraclitily
(Irogs)
ROIHI 16219 05 Mechanisms ol atherogenem in chronic
uremia (human, rats)
ROIHL 15315 05 Analysis ol interaction between CHS
vasomotor systems (cats, rals)
ROIHL 16606 11 Contraction in heart and other striated
muscles (Irogs)
POIHL 16607 05 0006 Calcium ion and control of
cardiovascular lunction Saicomere and contractile
dynamics of striated muscle cells (animals)
POIHL 1660/05 0007 Calcium ion and control of
cardiovascular function Ultrastructure and conlormation
in sarcoplasmic reticulum (rabbits)
POIHL 1668304 function and growth ol cardiac and
skeletal muscle
POIHL 16683-04 0001 Function and growth ol cardiac
and skeletal muscle Light chains ol the skeletal and
cardiac myosin molecule (rabbits. Irogs)
■ POIHL- 16683-04 0002 Function and growth ol cardiac
and skeletal muscle Myosin, actin, ATP, interaction in
solution
POIHL 16683-04 0003
and skelel.-l muscle
libers
POIHL- 16683 04 0006
and skeletal muscle
Function and growth of cardiac
Movements of SI moieties in muscle
Function and growth of cardiac
Chemical studies of the contractile
system Development ol new reagents
POIHL 17421 05 0004 Regulation and exchange in the
microcirculation Localization ol How regulation in the
microcirculation (cats, human)
ROlHL-1762803 Pulsatile pressure flow dynamics (dogs)
POIHL 17813-04 0007 Lung disease and the oxygenation
ol blood and tissue ■ Studies on the function of myoglobm
(dogs)
ROIHL 17853 03 Peripheral circulation in heart failure
(animals)
ROlHL-17932-04 Blood How regulation in muscle (cats)
ROIHL 18077 04 Smooth muscle cell organization and
Ca20 concentration control (chickens)
ROIHL 18145-03 Oxygen transport mechanisms in hypoxia
(dogs, rats, rabbits)
POIHL 18708-03 0008 Oxygen, energy and contractility in
cardiac tissue • Cardiac cell culture facility
ROIHL- 19008-02 Carbon dioxide diffusion in lung and
muscle tissues (dogs)
POlHL-19242-02 0001 Study of vascular smooth muscle ■
Energy metabolism and protein turnover in vascular smooth
muscle (rats)
ROlHL-1929903 Myoglobin and oxygen supply to heart
and muscle cells (rats, pigeons)
ROlHL-19848-02 Contractile activation by rapid
temperature jumps (frogs)
ROlHL-20408-03 Hyperlipidemia in diabetics during
muscular training (human)
' ROlHL-2046401 Regulation of cardiac and skeletal
muscle contraction (mammals)
POlHL-2055202 0001 The development and regression of
cardiac hypertrophy - Biochemical events in cardiac
hypertrophy (rats)
POIHL 20592-02 0003 Cell biology of cardiac and
skeletal muscle - Cellular magnesium and anion activities
in lon-specific microelectrodes (frogs)
POlHL-20592-02 0011 Cell biology of cardiac and
skeletal muscle Myosin and cytochrome oxidase
messenger RNAs (chicken)
POlHL-2098402 0003 Cellular mechanisms in cardiac
hypertrophy - Fast-kinetics ol myosin ATPase from normal
and hypertrophied heart (rabbits)
* R23HL-21332-02 Pulsatile regulation of flow in the
microcirculation (cats)
ROlHL-2147102 Structure-function studies on actin and
myosin (human, protozoa, rabbits, cattle)
ROlHL-21498-02 Pathophysiology of edema (rats, cats)
ROlHL-21812-02 Actions of drugs and ions on cardiac
membranes (rabbits, guinea pigs)
* R23HL-21901-01 Hypertension, microvascular control and
Regulation of tension and active state in
exercise (rats)
ROlHL-22401-01
the heart
ROlHL-22461-01 Cardiac tropomyosin and tropomyosin-
action interactions (rabbit)
ROlHL-22538-01 Myosin as a multi-enzyme complex (dogs,
rabbits)
POlHL-22619-01 0009 Cellular mechanisms of heart
failure - Sarcoplasmic reticulum in cardiac, skeletal and
smooth muscle (rabbits, dogs)
ROIHL 22664-01 Regulation of myocardial cell growth
(rats, guinea pigs)
ROlHL-22740-01 Behavior and cardiovascular disease-
Basic mechanisms (human)
R23HL-22975-01 Dynamics of autoregulation of muscle
blood flow (dogs)
ROlHL-22985-01 Properties and assembly of Z-disk
proteins (human, other species)
R13HL-2307201 Gordon Research Conference -Cardiac and
skeletal muscle (New Hampshire)
ROlHL-23128-01 Cardiac contractility-Ischemia and
hypoxia (rabbits, rats)
ROlHL-23615-01 Biochemistry of contractile proteins
(chicken, rabbit)
(contd)
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
**Onented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number
MUS
MUSCUUR DISORDERS
SEE ALSO HEART DISORDERS, MYOCARDITIS
SEE ALSO METABOLIC DISORDERS INBORN. MUSCUUR
DYSTROPHY
SEE ALSO METABOLIC DISORDERS INBORN. MYOTONIA
CONGENITA
SEE ALSO NEUROMOTOR DISORDERS
SEE ALSO NEUROMOTOR DISORDERS. NEUROMUSCUUR
(GENERAL)
ROlHL-05949-18 Biochemistry of muscle contraction (rats,
rabbits)
ROlHL-1253010 Emphysema-Respiratory function in
disease (human, dogs, rats)
** POlHL-1583506 0010 Study of muscles related to heart
disease - Muscle structure and reaction to injury (mice,
rats)
ROlHL-2147102 Structure-function studies on actin and
myosin (human, protozoa, rabbits, cattle)
MUSCULAR DISORDERS, MUSCLE NECROSIS
SEE ALSO HEART DISORDERS. CORONARY. MYOCARDIAL
INFARCT
P50HL-1765104 0038 Ischemic heart disease specialized
center of research - Cardiothermography (human, dog)
P50HL-1765104 0039 Ischemic heart disease specialized
center of research ■ Measurement and prediction of infarct
size (human, dog)
P50HL17665-04 0008 Study of ischemic heart disease ■
Core laboratory -CPK isoenzyme measurement and
myocardial necrosis evaluation
P50HL-1766504 0029 Study of ischemic heart disease ■
Myocardial protein synthesis and degradation in low oxygen
states (rabbit, dog)
ROlHL-2040103 Relationship of insulin to catechol
cardiomyopathy (rabbit, pig)
ROlHL-22741-01 Arteriovenous connections in extremity
revascularization (dogs)
ROlHL-23140-01 Determinants of irreversible ischemic
injury in heart (dog. rat)
MUSCULAR DISORDERS CHEMOTHERAPY
SEE ALSO MUSCLE PHARMACOLOGY
ROlHL-05806-18 Analysis of antiarrhythmic agents (dogs,
rabbits)
MUSCULAR DYSTROPHY
SEE METABOLIC DISORDERS INBORN, MUSCUUR
DYSTROPHY
MUSCULOSKELETAL SYSTEM (GENERAL)
SEE SKELETAL SYSTEM (GENERAL)
MUSSEL POISON
SEE TOXICOLOGY, PROTOZOAL TOXINS, SAXITOXIN
MUSTARDS, NITROGEN
SEE HALOALKYUMINES. NITROGEN MUSTARDS
MUTAGENS
SEE GENETICS. MUTAGENS
MUTANTS
SEE GENETICS. MUTATION. MUTANTS*
MUTATION
SEE GENETICS, MUTATION
MUTATION, CHROMOSOME
SEE GENETICS. MUTATION. GENE MUTATION. POINT
MUTATION
MYCOBACTERIUM BOVIS, BCG STRAIN
SEE BACTERIA. ACTINOMYCETALES. BACILLUS CALMEHE-
GUERIN*
MYCOBACTERIUM TUBERCULOSIS
SEE BACTERIA, ACTINOMYCETALES, MYCOBACTERIUM
TUBERCULOSIS*
MYCOPLASMA
SEE BACTERIA, MYCOPUSMATALES, MYCOPUSMA*
MYCOPLASMA PNEUMONIAE
SEE BACTERIA. MYCOPUSMATALES. MYCOPUSMA
PNEUMONIAE*
MYCOPLASMAL PNEUMONIA
SEE RESPIRATORY DISORDERS, PNEUMONIA MYCOPUSMAL
(PPLO)
MYCOSES, ASPERGILLOSIS
** P50HL-I538907 0010 Pulmonary SCOR-Hypersensitivity
pneumonitis - Clinical study -Pulmonary lesions due to non-
invasive aspergillosis
MYCOTOXINS
SEE TOXICOLOGY, MYCOTOXINS
MYELIN DEGENERATION
SEE NERVOUS DISORDERS, MYELINOPATHIES (GENERAL)
MYELINATION
SEE NERVOUS SYSTEM, MYELINATION
MYELINOPATHIES (GENERAL)
SEE NERVOUS DISORDERS, MYELINOPATHIES (GENERAL)
364
MYELOCYTIC, MYELOGENOUS, MYELOID
LEUKEMIA
SEE NEOPUSMS OF BLOOD AND RE SYSTEM, LEUKEMIA
MYELOID
MYELOPROLIFERATIVE DISORDERS (BONE
MARROW)
SEE NEOPUSMS OF BLOOD AND RE SYSTEM. BONE MARROW
NEOPUSMS. MYELOPROLIFERATIVE
MYELOSIS BONE AAARROW
SEE NEOPUSMS OF BLOOD AND RE SYSTEM, BONE MARROW
NEOPUSMS, MYELOPROLIFERATIVE
MYOBLASTS
SEE MUSCLE CELLS, MYOBUSTS
MYOCARDIAL AUGMENTATION, BAUOON
PUMPING AORTIC
SEE HEART PROSTHESIS, AUXILIARY. AORTIC BALLOON
PUMPING
MYOCARDIAL DEPRESSANTS
SEE CARDIOVASCUUR AGENTS, ANTIARRHYTHMIC AGENTS
MYOCARDIAL DISORDEIRS
SEE HEART DISORDERS, MYOCARDIAL DISORDERS
MYOCARDIAL INFARCT
SEE HEART DISORDERS, CORONARY, MYOCARDIAL INFARCT
MYOCARDIAL INFARCT SIZING
SEE HEART DISORDERS DIAGNOSIS, MYOCARDIAL INFARCT
SIZING
MYOCARDIAL INFARCT THERAPEUTIC AGENTS
SEE CARDIOVASCUUR AGENTS. CARDIOTONIC AND
CARDIOPROTECTIVE DRUGS (GENERAL)
MYOCARDIAL ISCHEMIA AND HYPOXIA
SEE HEART DISORDERS. CORONARY. MYOCARDIAL ISCHEMIA
AND HYPOXIA
MYOCARDIAL REVASCULARIZATION
SEE HEART REVASCUURIZATION
MYOCARDITIS
SEE HEART DISORDERS. MYOCARDITIS
MYOCARDIUM
SEE HEART, MYOCARDIUM
MYOCARDIUM INTERCALATED DISCS
SEE HEART. MYOCARDIUM INTERCAUTED DISCS
MYOCARDOSIS
SEE HEART DISORDERS. MYOCARDIAL DISORDERS
MYOCLONUS
SEE NEUROMOTOR DISORDERS. MYOCLONUS
MYOEPITHELIAL CELLS
SEE MUSCLE CELLS. MYOEPITHELIAL CELLS
MYOFIBRILS
SEE MUSCLES. MYOFIBRILS
MYOGENESIS
SEE MUSCLES. MYOGENESIS
MYOGLOBIN
SEE HEMOPROTEINS. MYOGLOBIN
MYOGLOBINOPATHIES
SEE HEMOPROTEINS. MYOGLOBINOPATHIES
MYOGLOBINURIA
SEE HEMOPROTEINS, MYOGLOBINURIA
MYOGRAPHY, ELECTROMYOGRAPHY
SEE MUSCLE FUNCTION, ELECTROMYOGRAPHY*
MYOKINASE
SEE PHOSPHOTRANSFERASES, ATP:AMP
PHOSPHOTRANSFERASE
MYONEURAL JUNCTION
SEE NEUROMOTOR SYSTEM, NEUROMUSCUUR JUNCTION
MYOPIA
SEE EYE REFRACTIVE DISORDERS, MYOPIA
MYOSIN
SEE MUSCLE PROTEINS (AND CONTRACTILE PROTEINS)
MYOSIN
MYOTACTIC RECEPTORS
SEE MUSCLE FUNCTION, MUSCLE STRETCH (RECEPTORS)
MYOTACTIC REFLEX
SEE MUSCLE FUNCTION, MUSCLE STRETCH REFLEX
MYOTONIA ATROPHICA
SEE METABOLIC DISORDERS INBORN, MYOTONIA ATROPHICA
MYOTONIA CONGENITA
SEE METABOLIC DISORDERS INBORN, MYOTONIA CONGENITA
MYOTONIC DYSTROPHY
SEE METABOLIC DISORDERS INBORN, MYOTONIA ATROPHICA
■Excludes routine methodology OR covers only general projects which preclude indexing at the specific level
Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects
See Appendix for investigator's name and grant number.
NAP
NAOASE
SEE N-GLYCOSYLHYDROUSES, NAD NUCLEOSIDASE
NAD LINKED ENZYMES
POlHL-06285-18 0178 Cardiovascular-respiratory
physiology and biochemistry - Biochemical regulation of
hypertrophy (rats, rabbits)
** ROlHL-20 116-01 Heart lactate dehydrogenase -The complex
with NADH (pig)
ROlHL-20544-02 Integrated regulation of myocardial
energy metabolism (rats, guinea pigs)
ROlHL-23161-01 0001 Biology of myocardial ischemia -
Mitochondrial lipid metabolism and cardiac ischemia (rat,
dog)
NAD NUCLEOSIDASE
SEE N-GLYCOSYLHYDROUSES. NAD NUCLEOSIDASE
NAD (H2)
SEE PYRIDINE NUCLEOTIDES. NICOTINAMIDE RIBOTIOES
NAD(H2)
NAD(P)H DEHYDROGENASE (QUINONE)
SEE OXIDOREDUCTASES. NAO(P)H DEHYDROGENASE
(OUINONE)
NAD(P)H:(QUINONE-ACCEPTOR)
OXIDOREDUCTASE
SEE OXIDOREDUCTASES, NAD(P)H DEHYDROGENASE
(QUINONE)
NADPH:ACCEPTOR OXIDOREDUCTASE
SEE OXIDOREDUCTASES, NADPH DEHYDROGENASE
NADPH-CYTOCHROME REDUCTASE
SEE OXIDOREDUCTASES. NADPH2 CYTOCHROME C
REDUCTASE
NADPH DEHYDROGENASE
SEE OXIDOREDUCTASES. NADPH DEHYDROGENASE
NADPH.FERRICYTOCHROME OXIDOREDUCTASE
SEE OXIDOREDUCTASES. NADPH2 CYTOCHROME C
REDUCTASE
NADPH2 CYTOCHROME C REDUCTASE
SEE OXIDOREDUCTASES. NADPH2 CYTOCHROME C
REDUCTASE
NADP LINKED ENZYMES
POlHL-16748-05 0004 Cellular and immunological basis
of pulmonary diseases - Cellular and immunological
processes in pulmonary defense systems
ROlHL-18502-03 Enzymatic regulation of platelet function
(human)
ROlHL-19628-03 Mechanisms of pulmonary alveolar
proteinoses (human, rats)
NALOXONE
SEE ALKALOIDS, MORPHINES, NALOXONE
NAPHTHYLAMINES, PROPRANOLOL
ROlHL-04666 19 Artificially paced hearts-Technology,
physiology (human, dogs)
ROlHL-0580618 Analysis of antiarrhythmic agents (dogs,
rabbits)
ROlHL-05875-18 Pathologic metabolic and physiologic
studies of heart (human, dogs, cats)
POlHL-06285-18 0154 Cardiovascular-respiratory
physiology and biochemistry - Function and viability of
critically ischemic myocardium (dogs)
POlHL-06285-18 0186 Cardiovascular-respiratory
physiology and biochemistry - Leukocyte hormone receptors
and cyclic nucleotides (tissue culture)
POlHL-06308-18 0011 Mechanisms and therapy of
circulatory disease - Blood flow and electrical dysfunction
in ventricular arrhythmia (human)
POlHL-06370-17 0014 Cardiopulmonary and renal
pathology research center - Quantitative morphology in
cardiac disease (human, rats, dogs)
POlHL-06835-17 0031 Cardiovascular disease ■ Synthesis
of potent antagonist of pressor action of angiotensin II
(animals)
POlHL-06835-17 0037 Cardiovascular disease - Cardiac
hypertrophy in spontaneously hypertensive rat
POlHL-06835-17 0045 Cardiovascular disease • Pressure-
volumerenin relationship in human hypertension
POlHL-06835-17 0046 Cardiovascular disease - Renin
activity during salt depletion In essential hypertension
(human)
POlHL-0683517 0051 Cardiovascular disease -
Cardiopulmonary volume in hypertension (human)
■* POlHL-06835-17 0061 Cardiovascular disease ■ Studies
in renal physiology (human, rats, dogs)
ROlHL-07835-17 Experimental hypertension and renal
circulation (rats, rabbits)
POlHL-07896-15 0054 Environmental biomedical research
program - Myocardial effects of hemorrhagic shock (dogs)
R01HL08311-14 Effects of drugs upon myocardial hypoxia
(dogs, turtles)
POlHL-08682-15 0026 Regulation of the cardiovascular
system - Hypertension-High renin vs low renin (dog)
POlHL-08682-15 0038 Regulation of the cardiovascular
system ■ Control of pulmonary circulation (dogs)
(contd)
NAR
ROIHI 09906 13 0025 Menibiane tiansport piocessas in
fad blood calls Machanism ol ptopianolol inducad Ca
dapandant K etilu* tiom human RBCs
POIHL 10342 13 0019 The integrated lunction ot
fespiiation and circulation Ceiebial ciiculalion and
metabolism (dogs)
ROIHL 10608 12 Oigo«inspeci(ic antibodies (human)
ROIHL 10914 10 Renal sodium tianspod in expeiimental
aldosteronism (dogs)
ROIHL 10942 09 Study ot genetic hypertension in rats
POIHI 11310 12 0078 Mechanisms ol cardiovascular
disease Ventricular arrhythmias in acute myocardial
infarction (dogs)
POIHL 11310 12 0079 Mechanisms o( cardiovascular
disease Electrophysiological studies ol complete heart
block (human)
POIHL 12373 10 0013 Cardiopulmonary physiology and
pathophysiology tftects of cardiovascular drugs on left
ventricular function (dogs)
P01HL12738 10 0001
clinical applications
drugs (human)
POIHL 1273810 0042
clinical applications
(cats)
PO1HL1273810 0094
clinical applications
(human, dogs)
P01HL1273810 0108
clinical applications
Physiologic pharmacology and its
Clinical pharmacology of cardioactive
Physiologic pharmacology and its
Centfogenic cardiac arrhythmias
Physiologic pharmacology and its
Ventricular function and structure
Physiologic pharmacology and its
Developmental electrophysiology and
pharmacology (human, animals)
POIHL 12738 10 0117 Physiologic pharmacology and its
clinical applications Ventricular arrhythmias in ischemic
heart disease (human)
POlHL-12738-10 0124 Physiologic pharmacology and its
clinical applications Counterpulsation on myocardial
ischemia measured by carbon dioxide tension (dogs)
POlHL-12738 10 0133 Physiologic pharmacology and its
clinical applications Pharmacologic antagonism of beta-
adrenergic blockade (dogs)
POlHL-12738 10 0134 Physiologic pharmacology and its
clinical applications Adenylate cyclase and cAMP
phosphodiesterase in cardiac development (dogs)
POlHL-13108-09 0017 Clinical heart transplantation ■
Electrophysiology of the transplanted denervated human
heart
P01HL1310809 0019 Clinical heart transplantation -
Effect of autonomic nervous system on arrhythmias
(human)
ROlHL-13315-08 Disposition of vasoactive hormones in
mammalian lung (rats, rabbits, human)
R01HL1366606 Pharmacology of genesis of cardiac
rhythmicity (rats, cats)
ROlHL-13917-20 Secretion and effects of adrenal
hormones (human, rabbits, sheep)
P50HL-14 192-08 0003 Specialized center of research in
hypertension - Prostaglandins as mediators of renin
secretion (human, dog)
POlHL-14388-07 0159 Regulation of the circulation in
pathological states - Early drug and diet interventions and
blood pressure development (rats)
POlHL-14388-07 0209 Regulation of the circulation in
pathological states - Neural regulation of vascular
resistance in human hypertension
POlHL-14388-07 0215 Regulation of the circulation in
pathological states - Left ventricle model in
pathophysiologic states
POlHL-14388-07 0223 Regulation of the circulation in
pathological states - Kallikrein-kinin system in hypertension
(rats)
POlHL-14388-07 0229
pathological states
(human)
ROIHL 14693-07 Survival value of physiological responses
to hypoxia (dogs)
ROlHL-14713-06 Hypothermia and the heart (bats, guinea
pigs)
ROlHL-14832-06 Myocardial cells -Autonomic and rhythmic
mechanisms (chick embryo, rats)
ROlHL-15002-07 Biochemical pharmacology of guanylate
cyclase in lung (cattle, rats)
ROlHL-15047-06 Digital computer analysis of the
electrocardiogram (human)
ROlHL-16076 06 Electrophysiology of fibrillation and
defibrillation (human)
ROlHL-16454-03 Vascular muscle reactivity in
hypertension (human, rats)
P01HL-16607-05 0003 Calcium ion and control of
cardiovascular function - Calcium transport in
sarcoplasmic membranes (animals)
Regulation of the circulation in
Mechanism of postural hypotension
Left ventricular function in exercise
Myocardial subcellular localization of
Dynamic control of coronary blood flow
Oxygen uptake at one minute of exercise
ROlHL-16656-06
(dogs)
ROlHL-16710-03
calcium (dogs)
R01HL-16760-05
(dogs)
ROlHL-17246-03
(human)
ROlHL-17355-04 Pulmonary vascular adiustments in
circulatory collapse (dogs, rats)
ROlHL-17366-05 Mechanisms in the production of renal
hypertension (rabbits, dogs)
365
POIHL 1/382 05 0002 Chemical mediators ot acute
pulmonary disorders Chemical mediators and respiratory
mechanics in guinea pigs
ROIHI 17459 03 Myocardial ischemia (dogs)
ROIHL 1/629 03 Developmental aspects ol cardiovajcular
function (human, cats, labbits)
P50HL 1/651 04 0002 Ischemic heart disease specialized
center ol research Reduction of myocardial ishemic in|ury
by pharmacologic agents (human, dog)
P50HL 17655 04 0009 Study ol ischemic heart disease
Random trial of medical and surgical therapy in unstable
angina (human)
P50HI 17665 04 0002 Study of ischemic heart disease
Reducing acute anterior myocardial infarction Beta
adrenergic blockade (human)
P50HL 17665 04 0012 Study of ischemic heart disease -
Myocardial ischemia -Cardiovascular perlormance in the
conscious baboon and dog
P50HL 17669 04 0008 Ischemic heart disease center
(SCOR) Segmental ventricular dysfunction during stress-
induced ischemia (dog. human)
P50HL 1766904 0012 Ischemic heart disease center
(SCOR) • Circulatory assistance (human, dog)
P50HL 17670 04 0009 Study ol ischemic heart disease
Surgical treatment of localized left ventricular dyssynergy
(human, dogs)
ROIHL 17749-03 Adrenocortical factors in human
hypertension (human)
ROIHL 17768-04 Development of collateral ventilation
(dogs, fish, horses)
ROIHL- 17865-04 Studies on aging -Effects ol sex
hormones (rats, dogs)
POIHL 17871-04 0009 Kidney, sodium, cardiac output,
arterioles and hypertension Kidney, sodium, cardiac
output, arterioles and hypertension
ROIHL 17909-04 Drug treatment of vascular scleroprotein
defects (human, turkeys)
ROIHL 18024-03 Regional myocardial llov» and function
relationships (dogs)
P50HL-183 18-03 0011 Pathogenesis and complibations ol
hypertension Adrenergic function -Renin and
mineralocorticoid activity (human)
P50HL-18323-04 0043 SCOR hypertension center -
Pharmacology -Renin-aldosterone mechanisms in essential
hypertension (human)
ROlHL-18537-04 Regional blood flov« after acute
myocardial injury (dogs)
ROlHL-18805-04 0004 Sudden cardiac death and the
onset of myocardial infarction - Sudden death survivors-
Clinical follow-up and therapy (human)
P50HL-18828-03 0005 Specialized center ol research in
thrombosis Platelet inflammatory factors in thrombosis
(human, guinea pig)
ROlHL-18948-03
(dogs, calves)
ROlHL-191 12-03
ROlHL-19127-03
imaging (rats)
ROlHL-19394-03
the heart (rats, guinea pigs, cats)
ROlHL-19782-02
heart (dogs)
ROlHL-20190-02
Pulseless How and circulatory assistance
Atherosclerosis studies (monkeys)
Synthesis of molecules lor myocardial
(dogs)
ROlHL-20199-02
in the rat
ROlHL-20455-03
Biochemistry and regulation ol taurine in
linea pigs, cats)
Pharmacologic studies on the ischemic
Pathogenesis of cardiac hypertrophy
Drug-induced alterations in infarct size
Role of systemic hypertension on diabetic
retinopathy (human)
ROlHL-20542-03 Regional hemodynamics in spontaneous
hypertension (rats)
ROlHL-20859-02 Beta adrenergic catecholamine receptor
R23HL-21151-02 Ischemic myocardium -Delivery of blood
flow and drugs (dogs)
ROlHL-21158-02 Cardiac receptors with vagal C-fiber
afferents (cats)
ROlHL-21221-02 Clinical antiarrhythmic and
pharmacodynamic studies
POlHL-2 1584-02 0005 Respiratory mechanics in normal
and abnormal slates - Regulation and behavior of airway
smooth muscle (human, animals)
ROlHL-21684-02 0001 Radionuclide infarct sizing and
therapy evaluation - Evaluating preservation of ischemic
myocardium by radioisotope methods (dog)
ROlHL-21684-02 0002 Radionuclide infarct sizing and
therapy evaluation - Evaluating myocardial imaging agents
in global and regional ischemia (rabbits)
ROlHL-21684-02 0005 Radionuclide infarct sizing and
therapy evaluation - Clinical evaluation ol radioisotope
imaging methods for quantifying infarct size
ROIHL-21742-01 Frequency-dependent drug actions in
cardiac muscle (rabbits)
ROlHL-21817-01 Catecholamines, blood pressure and
circulation
* R23HL-21973-01 Catecholamine metabolism and the heart
(human, guinea pigs)
•Excludes routine methodology OR covers only general projects which preclude
••Oriented significantly to above subiect.
ROlHL-22032-01
(human)
ROlHL-22296-01
ROlHL-22484 01
excitation (dogs)
ROlHL-22546-02
indexing at the specific level.
Cardiovascular events in hypertensives
Autonomic mechanisms in man
Neural control of cardiac conduction and
Baroreceptor reflex mechanisms in man
NAS
ROIHI 22508 01 pH ellecl in heart tall-. Influence ol
cardiac drugs (tissue culture, rats)
ROIHI 22581 02 Neurocirculatory control in diabalct
mellitus (human)
POIHI 22619 01 0010 Cellular mechaniimi ol heart
lailure Mitochondria in heart and -.mooth muscle (rabbilj.
rats, dogs)
ROIHI 22641 01 Ventilation, perfusion, and lyilcmic
arterial reflexes (dogs)
ROIHL 22/1801 Cardiovascular drug interactions-
Metabolism models (dogs)
ROIHL 22836 01
(rats)
ROIHL 22862 01
The spontaneously hypertensive kidnay
CNS-mediatad aflects ol antiarrhythmic
drugs (dogs)
ROIHL 22868 01
Presynaptic regulatory mechanisms in
hypertension (rats, dogs)
ROIHL 23025 01 Adaptive heart growth in neonates and
adults (rats)
ROIHL 23624 01 Effect ol drugs on ischemic cardiac cells
(dogs, guinea pigs, pigs)
ROIHL 23726 01 Treatment ol ventricular arrhythmias with
propranolol (human)
NOIHV 62960 00 Techniques to protect ischemic
myocardium and minimize infant size (human)
N01HV7294002
(human)
NOIHV 7294803
Therapy to protect ischemic myocardium
Coordinating center lor propranolol heart
trial (human)
* N01HV7294903
* NOIHV 72950-02
trial
* NOlHV-7295103
(human)
* NOlHV-72952 02
(huamn)
* NOlHV-72953-04
* NOIHV 72954-06
(human)
* NOIHV 72955-02
(human)
'* NOIHV 72956-02
(human)
■* NOlHV-72957-02
(human)
•* NOlHV-7295802
(human)
'* NOlHV-72959-04
(human)
•* NOlHV-72960-02
(human)
** NOlHV-72961-03
•* NOlHV-72963-02
(human)
•* NOlHV-72964-02
(human)
*• NOlHV-72965-02
" NOlHV-72966-03
** NOlHV-72967-02
(human)
*• NOlHV-72968-03
** NOlHV-72969-02
(human)
** NOlHV-72970-04
(human)
** NOlHV-82900-03
(human)
** NOlHV-82901-02
(human)
** NOlHV-82902-02
(human)
*• NOlHV-82903-02
(human)
** NOlHV-82904-02
(human)
" NOlHV-82905-02
(human)
" NOlHV-82906-02
(human)
•* NOlHV-82907-02
(human)
** NOlHV-82908-02
(human)
** NOlHV-82909-02
(human)
** NOlHV-82910-00
(human)
NARCOSIS
SEE SENSORY DEPRESSION. ELECTRONARCOSIS
NARCOSIS, INERT GAS
SEE INJURIES. DYSBARISM, INERT GAS NARCOSIS
NARCOTICS
SEE PSYCHOPHARMACOLOGICAL AGENTS. NARCOTICS
NASAL, NOSE
** P50HL-19157-02 0003 Studies in cystic fibrosis and
bronchiolitis - Nasal mucosal function in patients with
cystic fibrosis
P50HL-19157-02 0004 Studies in cystic fibrosis and
bronchiolitis - Macromolecular regulators of mucus
secretion -Invertebrate mode!
(contd)
ECG center for proprancolo heart trial
Central laboratory for propranolol heart
Clinical center lor propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center lor propranolol heart trail
Clinical center for propranolol heart trial
Clinical center propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center lor propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center lor propranolol heart trial
Clinical center lor propranolol trial
Clinical center lor propranolol heart trial
Clinical center lor propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
Clinical center for propranolol heart trial
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
. -c>»^ Wl<Al»^.^tf.'
NAS
NASAL AIRFLOW MEASUREMENTS
SEE RESPIRATORY DISORDERS DIAGNOSIS, RESPIRATORY
AIRFLOW MEASUREMENTS*
NASAL DISORDERS, EPISTAXIS
P01HL1743005 0001 Control of coagulation ■ Porcine
von Willebrand's disease
NASAL DISORDERS, RHINITIS
R01HL-23631-01 Immunogenetic factors in allergic
respiratory diseases (human)
NASAL SALT GLAND
SEE BODY FLUID BALANCE, IONIC. SALT GLAND
NASOPHARYNX
SEE ORALPHARYNGEAL, NASOPHARYNX
NATIONAL HIGH BLOOD PRESSURE EDUCATION
RESEARCH PROGRAM COMMITTEE
** R25HL-1840603 Adherence to hypertensive medical
regimens (human)
** R25HL-184 14-03 Hypertension-Family strategies for
patient adherence
** R25HL 1841803 Role of a supporting partner in
adherence (human)
** R25HL-18424-03 Blood pressure education in an industrial
setting (human)
NATRIURESIS
SEE KIDNEY FUNCTION. SALURESIS
NATURAL PRODUCTS
SEE ALSO BIOLOGICAL PREPARATIONS AND STANDARDIZATION
SEE ALSO PUNTS EXTRACTS
SEE ALSO PUNTS PROTEINS
R01HL-07502 13 Phytochemistry of the genus thalictrum
(dogs, plants)
ROlHL-12971-15
R01HL-17341-03
prostaglandins
R01HL-18253-03
ROlHL-19287-03
Reactions of alkoloids and their analogs
Practical total synthesis of
Structure of the palytoxins
The antihypertensive function of the
renal medulla (human, rats, rabbits)
R01HL-20016-03 Chelator development for thalassemia
(human, mice, rats, dogs, monkeys)
ROIHL 20579-02 Synthesis of therapeutically important
alkaloids
P01HL-20993-02 0005 Population dynamics of arterial
cells in atherogenesis - Drugs other than hypolipidemic
drugs affecting atherosclerosis (swine, rabbits)
ROlHL-22201-01 Pharmacology and chemistry of
nudibranch toxins (guinea pigs, rats, mice)
ROlHL-22778-01 Total synthesis of natural cardiotonic
ionophores
NAUSEA
SEE GASTROINTESTINAL SIGNS-SYMPTOMS, NAUSEA
NEARSIGHTEDNESS
SEE EYE REFRACTIVE DISORDERS, MYOPIA
NECK AND HEAD INJURIES
SEE INJURIES, HEAD AND NECK
NECROCYTOSIS
SEE CELL DEATH
NECROSIS
SEE DISEASES, PATHOLOGIC PROCESSES, NECROSIS
NEGATIVE PRESSURE BREATHING
SEE RESPIRATORY ASSIST AND OXYGEN ADMINISTRATION,
NEGATIVE PRESSURE BREATHING
NEGROES
SEE SOCIAL GROUPS, ETHNIC. AMERICANS, BUCK
AMERICANS
NEGROID RACE
SEE SOCIAL GROUPS, RACIAL STOCKS, BUCK RACE
NEISSERIA MENINGITIDIS
SEE BACTERIA, NEISSERIACEAE, NEISSERIA MENINGITIDIS*
NEMATODE ANTIGENS
SEE IMMUNOLOGY, ANTIGENS HELMINTHIC
NEOMYCIN
SEE ANTIBIOTICS, NEOMYCIN
NEON
SEE GAS ELEMENTS. NEON
NEONATAL
SEE CHILDREN. INFANT NEWBORN (BIRTH TO 4-6 WKS)
NEONATAL MORTALITY
SEE CHILDREN, INFANT AND CHILD MORTALITY
NEONATAL MORTALITY, ANIMAL
SEE AGE (ANIMAL), INFANTS MORTALITY
NEOPLASMS
P01HL-06314-17 0054 Immunologic mechanisms in
cardiovascular disease - Physiology of cell communications
(mice, frogs, guinea pigs)
366
NEOPLASMS, ADENOMA
" P01HL-06835-17 0048 Cardiovascular disease ■
Aldosterone producing adenoma prediction of curability
(human)
P01HL-06835-17 0049 Cardiovascular disease - Selective
hypoaldosteronism (human)
NEOPLASMS, ASCITES TUMORS
SEE ALSO NEOPUSMS. CARCINOMA. EHRLICH TUMOR
ROlHL-14781-08 Lipid deposition in mammalian cells
(mice)
NEOPLASMS, CANCER COMPLICATIONS OF
P60HL-17265-04 0006 Community blood resource center
support ■ Research-Evaluation of platelet transfusions
(human, dog)
NEOPLASMS, CANCER COMPUCATIONS OF,
INFECTIONS
P60HL 17265-04 0009 Community blood resource center
support - Research -Developing granulocyte transfusion
therapy (human, rabbit)
NEOPLASMS, CARCINOMA, EHRLICH TUMOR
ROIHL 1599105 Evaluation of heart stimulants in sea
anemones
NEOPLASMS, DRUG INDUCED
NOIHV 62900-00 Study of breast cancer and reserpine use
(human)
NEOPLASMS, EMBRYONIC
SEE ALSO NEOPUSMS OF URINARY TRACT, KIDNEY
NEOPUSMS, NEPHROBUSTOMA
ROlHL-11511-10 Structure of ferritin and its role in iron
metabolism (horse, rats, human)
NEOPLASMS, VIRUS INDUCED
R23HL-1959401 Tropocollagen and tropoelastin uptake in
lung cells (human)
NEOPLASMS CHARACTERISTICS, MOLECULAR
LEVEL STUDIES
ROlHL-14781-08 Lipid deposition in mammalian cells
(mice)
ROlHL-18181-04 Surfactant metabolism -Alveolar cells and
lung disease (mice, rabbits)
NEOPLASMS CLASSIFICATION AND STAGING
ROlHL-16651-05 Evaluation of steroid therapy in
sarcoidosis (human)
NEOPLASMS DIAGNOSIS
ROlHL-1151110 Structure of ferritin and its role in iron
metabolism (horse, rats, human)
R01HL12648-09 Catecholamine metabolism In
hypertensive diseases (human)
ROlHL-13722-08 Acid and alkaline Mpases in aortas (rats.
rabbits, human)
** P01HL-16748-05 0006 Cellular and immunological basis
of pulmonary diseases - Sarcoidosis -Studies »»ith bronchial
lavage (human)
ROlHL-17364-04 'Big renin' -Biochemical and clinical
studies (human)
ROlHL-19077-01 Biochemistry and molecular biology of
sarcoidosis (human, rabbits)
NEOPLASMS DIAGNOSIS, BREAST NEOPLASMS
DIAGNOSIS, MAMMOGRAPHY*
POlHL-04664-18 0007 Cardiovascular and lung dynamics
■ Development and application of ultrasound imaging
techniques
NEOPLASMS DIAGNOSIS, RADIODIAGNOSIS
ROlHL-18744-03
drug analogs
** R23HL-21253-01
image analysis
ROlHL-22371-01
radiation
Preparation of radiopharmaceuticals from
Anatomical models in computer-aided
Vascular changes in lung exposed to
NEOPLASMS DIAGNOSIS, RADIOISOTOPE
DIAGNOSIS
ROlHL-20761-02 Study of cerebral blood flow with stable
xenon and computerized tomography
NEOPLASMS EPIDEMIOLOGY
SEE NEOPUSTIC DISEASE EPIDEMIOLOGY-STATISTICS
NEOPLASMS GENETICS
SEE ALSO NEOPUSMS CHARACTERISTICS. MOLECUUR LEVEL
STUDIES
ROlHL-1151110 Structure of ferritin and its role in iron
metabolism (horse, rats, human)
NEOPLASMS IMMUNOLOGY
** P01HL-09011-15 0013 A research and resource program
in blood A quantitative study of immunological
enhancement (mice)
ROIHL- 194 29-03 Phagocytosis -Ingestion in alveiolar
macrophages (rabbits)
NEOPLASMS IMMUNOLOGY, TUMOR
ANTIBODIES
R01HL-10036-13 Biology of red cell antigen-antibody
reaction (human)
NEO
NEOPLASMS lAAMUNOLOGY, TUMOR ANTIGENS
ROlHL-08696-15 0011 Orthotopic heart transplantation -
Transplantation immunology-lmmunodepressive factor
(human, dogs)
NEOPLASMS METASTASIS
SEE NEOPUSTIC GROWTH, NEOPUSMS METASTASIS
NEOPLASMS OF BILIARY TRACT, LIVER
NEOPLASMS, HEPATOMA
R01HL-17818-05 Metabolism of cholesterol and cholesterol
in man (also rats, monkeys)
POlHL-22633-01 0002 Cellular and molecular biology of
lipoprotein metabolism - Sterol metabolism in tissue
culture cells
POlHL-22633-01 9001
lipoprotein metabolism
Cellular and molecular biology of
Tissue culture core
•Excludes routine methodology OR covers only general projects which preclude indexing
"Oriented significantly to above subject.
at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
NEOPLASMS OF BLOOD AND RE SYSTEM, BONE
MARROW NEOPLASMS, MULTIPLE MYELOMA
R01HL15722-06 Hemorrheology studies related to in vivo
blood flow (human)
P01HL19259-03 0001 Digoxin-specific antibody in human
therapy - Primary structure of monoclonal antibodies
(rabbits)
NEOPLASMS OF BLOOD AND RE SYSTEM, BONE
AAARROW NEOPLASMS, MYELOPROLIFERATIVE
*• ROlHL-12972-09 Glutathione deficiency in red cells
(sheep, dogs)
NEOPLASMS OF BLOOD AND RE SYSTEM,
HODGKIN'S DISEASE
P01HL-06314-17 0067 Immunologic mechanisms in
cardiovascular disease ■ Mitogenic and antigenic activation
of lymphocyte sub-populations
** POlHL-06370-17 0018 Cardiopulmonary and renal
pathology research center - Cytochemistry and immunology
of lymphoproliferative disorders (human)
NEOPLASMS OF BLOOD AND RE SYSTEM,
LEUKEMIA
ROlHL-17462-03 Role of glycosphingolipids in platelet
aggregation (rats, human, dogs)
ROlHL-21548-01 Pathogenesis of pulmonary
thromboembolic disease (human, mammals)
NEOPLASMS OF BLOOD AND RE SYSTEM,
LEUKEMIA, ERYTHROLEUKEMIA
ROlHL-03357-21 Humoral control of blood cell formation
and release (rats, mice)
POlHL-21016-02 0012 Sickle cell anemia and other
hemoglobinopathies - Stimulation of Hb F synthesis in a
permanent cell line
NEOPLASMS OF BLOOD AND RE SYSTEM,
LEUKEMIA ACUTE
NOlHB-62963-03 International bone marrow transplant
registry
NOlHB-6296403 International bone marrow transplant
registry
P60HL-17265-04 0009 Community blood resource center
support - Research -Developing granulocyte transfusion
therapy (human, rabbit)
NEOPLASMS OF BLOOD AND RE SYSTEM,
LEUKEMIA CHRONIC
ROlHL-20925-01 The acetylation of fetal hemoglobin
(human)
NEOPLASMS OF BLOOD AND RE SYSTEM,
LEUKEMIA MYELOID
POlHL-06314-17 0047 Immunologic mechanisms in
cardiovascular disease - Role of intravascular coagulation
(human, animals)
ROlHL-20856-02 Platelet transfusions-Usage and
complications (human)
ROlHL-20925-01 The acetylation of fetal hemoglobin
(human)
NEOPLASMS OF BLOOD AND RE SYSTEM,
LYMPHOMA
SEE ALSO NEOPUSMS OF BLOOD AND RE SYSTEM
HODGKIN'S DISEASE
SEE ALSO NERVOUS DISORDERS CENTRAL. MAREK'S DISEASE
POlHL-06370-17 0018 Cardiopulmonary and renal
pathology research center • Cytochemistry and immunology
of lymphoproliferative disorders (human)
ROlHL-08696-15 0011 Orthotopic heart transplantation -
Transplantation immunology-lmmunodepressive factor
(human, dogs)
NEOPLASMS OF BLOOD AND RE SYSTEM,
LYMPHOSARCOMA
SEE ALSO NEOPUSMS OF BLOOD AND RE SYSTEM.
HODGKIN'S DISEASE
** P01HL-0637017 0018 Cardiopulmonary and renal
pathology research center - Cytochemistry and immunology
of lymphoproliferative disorders (human)
NEOPLASMS OF BLOOD AND RE SYSTEM, MAST
CELL NEOPLASMS
R01HL-22402-01 Heparinbiophysical, chemical and
biological aspects (mice, human)
(contd)
:^^^^SSS>?v.
NEO
NEOPLASMS OF BRAIN
SEE ALSO NEOPUSMS OF NERVOUS SYSTEM
POIHL 138S1 16 Cyclolton produced isotopes in biology
and medicine (human, animals)
NEOPLASMS OF CARDIOVASCULAR SYSTEM
ROIHl 1S781 06 Guided vasculai obliteialion of CNS
vasculai lesions (human)
NEOPLASMS OF CARDIOVASCULAR SYSTEM,
HEMANGIOENDOTHELIOMA
POIHL 16851 04 0008 Human red cell membiane in
health and disease Force balance in red cell interactions
(human)
NEOPLASMS OF CARDIOVASCULAR SYSTEM,
HEMANGIOMA
P60HL 14230 07 0095 A/S SCOR Lipids, atherosclerosis
and thrombosis Blood platelet adherence to endothelial
smooth muscle cells, fibroblast (human)
NEOPLASMS OF ENDOCRINES
SEE ALSO NEOPLASMS OF NERVOUS SYSTEM. CARCINOID
SEE ALSO NEOPLASMS OF NERVOUS SYSTEM. PARAGANGLIA
NEOPUSMS. PHEOCHROMOCYTOMA
ROIHL 1580806 Role of angiotensinogen in hypertension
and stroke (human, rabbits)
NEOPLASMS OF ENDOCRINES, ADRENAL
GLANDS NEOPLASMS
** POlHL-0683517 0048 Cardiovascular disease
Aldosterone producing adenoma prediction of curability
(human)
P01HL06835-17 0049 Cardiovascular disease Selective
hypoaldosteronism (human)
R01HL0697518 Pathogenesis and prevention of
hypertension (rats)
ROlHL-1 1046-12 Renin, angiotensin, steroids, ions and
blood pressure (human, sheep, rabbits)
ROlHL-13917 20 Secretion and effects of adrenal
hormones (human, rabbits, sheep)
NEOPLASMS OF NERVOUS SYSTEM
SEE ALSO NEOPLASMS OF BRAIN
ROlHL-12648-09 Catecholamine metabolism in
hypertensive diseases (human)
NEOPLASMS OF NERVOUS SYSTEM, CARCINOID
** POlHL-1438807 0230 Regulation of the circulation in
pathological states Effects of indomethacin in patients
with carcinoid syndrome
NEOPLASMS OF NERVOUS SYSTEM,
NEUROBLASTOMA
ROlHL-2223901 The molecular basis of electrical
excitability (chick embryos, rats)
NEOPLASMS OF NERVOUS SYSTEM,
PARAGANGLIA NEOPLASMS,
PHEOCH ROMOCYTOMA
ROlHL-1104612 Renin, angiotensin, steroids, ions and
blood pressure (human, sheep, rabbits)
P50HL-1415908 0021 Specialized center of research in
hypertension ■ Genetic studies of the physiology of
hypertension (human, rats)
P50HL- 14 159-08 0024 Specialized center of research in
hypertension - Core resources (clinical, animal models)
ROlHL-18148-04 Adrenal catecholamine secretion
NEOPLASMS OF REPRODUCTIVE SYSTEM,
BREAST NEOPLASMS
SEE ALSO NEOPLASMS, CARCINOMA. EHRLICH TUMOR
ROlHL-15685-05 Hemopoietic regulators produced in cell
culture (human, animals)
** N01HV-62900-00 Study of breast cancer and reserpine use
(human)
NEOPLASMS OF REPRODUCTIVE SYSTEM MALE,
PROSTATE NEOPLASMS
P01HL04664-18 0008 Cardiovascular and lung dynamics
- Micrographic video imaging technique
R01HL19839-09 Factors in youth predisposing to chronic
diseases (former college students)
NEOPLASMS OF RESPIRATORY SYSTEM,
BRONCHIAL NEOPLASMS
ROlHL-22371-01 Vascular changes in lung exposed to
radiation
NEOPLASMS OF RESPIRATORY SYSTEM, LUNG
NEOPLASMS
SEE ALSO RESPIRATORY DISORDERS. PULMONARY FIBROSIS
AND GRANULOMAS
P50HL14153-07 0001 Johns Hopkins Lung Center-
Chronic diseases of airways Genetic and environmental
(actors in chronic pulmonary disease (human)
** ROlHL-18181-04 Surfactant metabolism -Alveolar cells and
lung disease (mice, rabbits)
R23HL-19594-01 Tropocollagen and tropoelastin uptake in
lung cells (human)
ROlHL-20675-02 Alveolar macrophage function in man
ROlHL-2 11 56-02 Antitrypsin and other causes of chronic
lung disease
367
R23HL 21894 01 Pulmonary angiotensin converting on/yme
(cattle)
ROIHL 22302 01 Immune responses in the human lung
(also labbits. monkeys)
■* ROIHL 22371 01 Vascular changes in lung exposed to
radiation
NEOPLASMS OF SKELETAL SYSTEM, OSTEOGENIC
SARCOMA
POIHL 10436 13 0005 A multidisciplinary study of
congenital heart disease Pulmonary physiology in
congenital heart disease (human)
ROIHL 1552605 Respiratory mechanics in children
ROIHL 22371 01 Vascular changes in lung exposed to
radiation
NEOPLASMS OF URINARY TRACT, KIDNEY
NEOPLASMS, NEPHROBLASTOMA
ROIHL 1736404 Big renin' Biochemical and clinical
studies (human)
NEOPLASMS RELATED INTEREST, GRANULOMA
SEE ALSO NEOPLASMS OF BLOOD AND RE SYSTEM.
HODGKINS DISEASE
SEE ALSO RESPIRATORY DISORDERS. PULMONARY FIBROSIS
AND GRANULOMAS
POIHL 16769-05 0003 Pathobiologic and host defense
reactions in the lung Pathobiologic mechanisms of
delayed sensitivity reactions in the lung (animals)
POlHL-16769-05 0010 Pathobiologic and host defense
reactions in the lung - Bronchus associated lymphoid
tissue and delayed hypersensitivity (rabbits)
ROlHL-19077 01 Biochemistry and molecular biology of
sarcoidosis (human, rabbits)
NEOPLASMS RELATED INTEREST, SARCOIDOSIS
SEE ALSO VIRUSES, HERPESVIRUSES, EB VIRUS
P50HL-14 187-07 0014 Pulmonary SCOR -Chemical
mediators in pulmonary vascular responses • Metabolism
and actions of vasoactive peptides in lung (human,
mammals)
P50HL- 1506 1-07 0006 Response of lung to injury -
Complement synthesis by pulmonary macrophages (guinea
pigs, human)
•* ROIHL 16651-05 Evaluation of steroid therapy in
sarcoidosis (human)
" POlHL-16748-05 0006 Cellular and immunological basis
of pulmonary diseases Sarcoidosis-Studies with bronchial
lavage (human)
POlHL-1676905 Pathobiologic and host defense reactions
in the lung
Pathobiologic and host defense
Immunogenetic factors in
M
Pathobiologic and host defense
Electron microscopy and tissue
POlHL-16769-05 0007
reactions in the lung
sarcoidosis (human)
POlHL-16769-05 0009
reactions in the lung -
culture core laboratory
POIHL- 178 13-04 0001 Lung disease and the oxygenation
of blood and tissue - Diffuse interstitial lung disease -
Pathophysiology (human, dogs)
POlHL-17813-04 0002 Lung disease and the oxygenation
of blood and tissue - Diffuse interstitial lung disease -
Ultrastructural abnormalities (human)
ROlHL-1907701 Biochemistry and molecular biology of
sarcoidosis (human, rabbits)
P50HL-1917102 0003 Pulmonary SCOR-Lung injury by
childhood infections Natural history, host defense defects-
Children with chronic pulmonary disease
POlHL-197 17-02 0038 Response of the lung to injury -
Interstitial lung disease -Clinical, pathologic and
epidemiologic
POlHL-19717-02 0041 Response of the lung to injury -
Cellular immunity in interstitial lung disease (human)
ROlHL-19731-03
(human)
ROlHL-20675-02
ROlHL-21156-02
lung disease
R23HL-21894-01
(cattle)
NOlHR-62935-02
Collagen in interstitial fibrosis of lung
Alveolar macrophage function in man
Antitrypsin and other causes of chronic
Pulmonary angiotensin converting enzyme
Histocompatibility antigens -Evolution of
respiratory hypersensitivity (human)
NEOPLASMS RELATED INTEREST, SARCOIDOSIS,
KVEIM FACTOR
Cellular and immunological basis
Sarcoidosis-Studies with bronchial
POIHL-16748-05 0006
of pulmonary diseases
lavage (human)
POlHL-16769-05 0007
reactions in the lung -
sarcoidosis (human)
POlHL-16769-05 0009
reactions in the lung -
culture core laboratory
Pathobiologic and host defense
Immunogenetic factors in
Pathobiologic and host defense
Electron microscopy and tissue
NEOPLASMS STAGING
SEE NEOPLASMS CUSSIFICATION AND STAGING
NEOPLASMS SURGERY
** POlHL-06835-17 0048 Cardiovascular disease -
Aldosterone producing adenoma prediction of curability
(human)
POlHL-06835 17 0049 Cardiovascular disease - Selective
hypoaldosteronism (human)
NEO
NEOPLASMS TRANSPLANTATION
POIHl 09011 15 0013 A leicaiili ■uu\ ii-;imit.e program
in blood A quantitative \tu6i ol iiiimmiimiIijki' iil
enhancement (mice)
ROIHl 18148 04 Adrenal catecholamine secietion
NEOPLASMS VASCULAR SUPPLY
ROIHI 22371 01 Vascular changes in lung exposed to
r;idiation
NEOPLASMS VASCULAR SUPPLY, TUMOR
ANGIOGENESIS FACTOR
ROIHL 1774/04 Endothelial injury and regeneration (rati)
ROIHL 20197 02 Maintenance and repair of vascular
endothelium (human, animals)
NEOPLASTIC ANTIBODIES
SEE NEOPLASMS IMMUNOIOGY, TUMOR ANTIBODIES
NEOPLASTIC antigen:
SEE NEOPLASMS IMMUNOLOGY, TUMOR ANTIGENS
NEOPLASTIC CELLS
R01HL07652 14 Destruction of red blood cells in
hemolytic anemias (human, guinea pigs)
ROIHL 18148 04 Adrenal catecholamine secretion
** POIHL 18827-02 0003 Platelet vessel wall interactions in
thrombogenesis Tumoi cell and platelets in
thrombogenesis and metastasis (human, animals)
NEOPLASTIC CELLS, HELA CELLS
ROIHL 1363008 Control of glycogen synthesis in heart
(cattle)
NEOPLASTIC DISEASE EPIDEMIOLOGY-
STATISTICS
POlHL-14388-07 9004 Regulation of the circulation in
pathological states Core biostatistics unit
** ROIHL 16651 05 Evaluation of steroid therapy in
sarcoidosis (human)
** ROIHL 22472 01 Smoking risk factor reduction
Maintenance strategies (human)
** NOlHV-62900-00 Study of breast cancer and reserpine use
(human)
NEOPLASTIC GROWTH
POIHL 09011-15 0013 A research and resource program
in blood A quantitative study of immunological
enhancement (mice)
ROlHL-17747-04 Endothelial injury and regeneration (rats)
NEOPLASTIC GROVrrn, NEOPLASMS
METASTASIS
P60HL- 17265-04 0006 Community blood resource center
support - Research-Evaluation of platelet transfusions
(human, dog)
ROlHL-18519-03 Albumin, endothelium and
hemocompatibility (human, dog, cattle, rabbit)
** POlHL-18827-02 0003 Platelet vessel wall interactions in
thrombogenesis - Tumor cell and platelets in
thrombogenesis and metastasis (human, animals)
ROlHL-22875-01 Crotalase-Chcmistry. physiology, clinical
potential (rats, rabbits)
NEOPLASTIC THERAPY
SEE ALSO NEOPLASMS SURGERY
ROlHL-2287501 Crotalase-Chemistry. physiology, clinical
potential (rats, rabbits)
NEOPLASTIC THERAPY, ANTINEOPLASTIC
AGENTS
SEE ALSO ANTIBIOTICS. ANTINEOPLASTIC ANTIBIOTICS
(GENERAL)
SEE ALSO NEOPLASTIC THERAPY. CANCER CHEMOTHERAPY
ROlHL-07502-13 Phytochemistry of the genus thalictrum
(dogs, plants)
ROlHL-12971-15 Reactions of alkoloids and their analogs
ROlHL-18245-03 Transition state analog inhibitors of
thrombin (human, cattle)
R01HL-18253-03 Structure of the palytoxins
ROlHL-22532-01 Inhibitors of cholesterol biosynthesis
(rats. mice, yeast)
NEOPLASTIC THERAPY, CANCER
CHEMOTHERAPY
** POlHL-14388-07 0230 Regulation of the circulation in
pathological states - Effects of indomethacin in patients
with carcinoid syndrome
R01HL-15526-05 Respiratory mechanics in children
ROIHL 16651-05 Evaluation of steroid therapy in
sarcoidosis (human)
RGlHL-18259-03 Controlled intratissue release of
prostaglandins
ROlHL-19077-01 Biochemistry and molecular biology of
sarcoidosis (human, rabbits)
ROlHL-20856-02 Platelet transfusions-Usage and
complications (human)
NEOPLASTIC THERAPY, CANCER RADIOTHERAPY
ROlHL-15526-05
" ROlHL-22371-01
radiation
Respiratory mechanics in children
Vascular changes in lung exposed to
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level
**Ofiented significantly to above subject.
M Grant has stibprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
NEO
NEOPLASTIC TRANSFORMATION
ROlHL-0912514 Ultrastructural cytochemistry (human,
chick)
** ROlHL-13722-08 Acid and alkahne hpases in aortas (rats.
rabbits, human)
P01HL1676905 0010 Pathobiologic and host defense
reactions in the lung • Bronchus associated lymphoid
tissue and delayed hypersensitivity (rabbits)
NEOPLASTIC TRANSFORMATION,
CARCINOGENESIS, CHEMICAL
R01HL17921-04 Peroxy radicals to prostaglandins in
vessels and lung
NEOPLASTIC TRANSFORMATION,
CARCINOGENS (GENERAL)
SEE ALSO GENETICS. MUTAGENS
SEE ALSO PLANTS EXTRACTS
ROlHL-1965403 Biochemical-pharmacological evaluation
of lung cells (rabbits)
NEOPLASTIC TRANSFORMATION,
CARCINOGENS, CHEMICAL
POlHL-03174 23 0011 Mechanisms of acute vascular
reaction to injury Mutagen metabolism by artery wall in
etiology of atherosclerosis (human, animals)
POlHL-09011-15 0021 A research and resource program
in blood - Regulation of transfer RNA methylating enzymes
(rats. E coli)
ROlHL-13619-09 Microsomal electron transport in liver
and heart (human, mammals)
NEOSTIGMINE
SEE PHENYUMINES. NEOSTIGMINE
NEOSYNEPHRINE
SEE PHENOLIC AMINES. NEOSYNEPHRINE
NEPHRECTOMY
SEE KIDNEY SURGERY. NEPHRECTOMY
NEPHRITIS
SEE KIDNEY DISORDERS, NEPHRITIS
NEPHRITIS INTERSTITIAL
SEE KIDNEY DISORDERS. NEPHRITIS INTERSTITIAL
NEPHROBLASTOMA
SEE NEOPLASMS OF URINARY TRACT. KIDNEY NEOPUSMS,
NEPHROBLASTOMA
NEPHRON
SEE KIDNEY. RENAL TUBULES
NEPHROSCLEROSIS
SEE KIDNEY DISORDERS. NEPHROSCLEROSIS
NEPHROSCLEROSIS (ARTERIOLAR)
SEE KIDNEY DISORDERS. NEPHROSCLEROSIS
NEPHROSIS
SEE KIDNEY DISORDERS, NEPHROSIS
NEPHROTIC SYNDROME
SEE KIDNEY DISORDERS. NEPHROTIC SYNDROME
NEPHROTOXINS
SEE KIDNEY TOXINS. NEPHROTOXINS
NERVE CELLS
SEE NERVOUS SYSTEM. NEUROGLIA
SEE NERVOUS SYSTEM. NEURONS
NERVE ENDINGS (GENERAL)
SEE NERVOUS SYSTEM. NERVE ENDINGS (GENERAL)
NERVE GROWTH FACTOR
SEE ALSO NEUROSURGERY. SYMPATHECTOMY.
IMMUNOSYMPATHECTOMY
R01HL-20604-03 Sympathectomy -Cardiovascular and
molecular pharmacology (animals)
** R01HL-20610-02 Nerve grovKth factor and obstructive
cardiomyopathy (dogs)
NERVE IMPULSE FACILITATION
SEE NEUROPHYSIOLOGY. NERVE IMPULSE FACILITATION
NERVE IMPULSE INHIBITION
SEE NEUROPHYSIOLOGY. NERVE IMPULSE INHIBITION
NERVE IMPULSE INITIATION
SEE NEUROPHYSIOLOGY. NERVE IMPULSE INITIATION
NERVE REGENERATION
SEE NERVOUS SYSTEM REGENERATION
NERVES (GENERAL)
SEE NERVOUS SYSTEM, NERVES (GENERAL)
NERVES DEGENERATION
SEE NERVOUS DISORDERS. NERVES DEGENERATION
NERVOUS DISORDERS (GENERAL)
SEE ALSO NEUROLOGIC MANIFESTATIONS
SEE ALSO NEUROMOTOR DISORDERS
P01HL-04664-18 0008 Cardiovascular and lung dynamics
- Micrographic video imaging technique
368
" P01HL-07896-15 0029 Environmental biomedical research
program - Oxygen-helium diving resulting in high pressure
nervous syndrome (human, animals)
ROIHL 11614-11 Trace elements in nutrition (chickens.
rats, human)
ROlHL-16325-03 Breathing patterns in man
R01HL-18606-04 Pathogenesis and measurement of
pulmonary edema (human, rabbits, dogs)
ROlHL-22258 01 New aspects of pharmacology related to
carbonic anhydrase
NERVOUS DISORDERS, MYELINOPATHIES
(GENERAL)
SEE ALSO LIPOGRANULOMATOSES. CEREBROTENDINOUS
XANTHOMATOSIS
ROlHL-02477-23 Biosynthesis and function of lipids
(microorganisms, rats)
ROlHL-18623-12 Physical chemistry of biologically active
lipids (bacteria, plant, cattle, human)
ROIHL 2040003 Diabetic neuropathy and peripheral
vascular diseases (human, hamsters)
NERVOUS DISORDERS, MYELINOPATHIES,
MULTIPLE SCLEROSIS
ROlHL-19839-09 Factors in youth predisposing to chronic
diseases (former college students)
NERVOUS DISORDERS, NERVES DEGENERATION
R01HL-16511-04 Sympathetic afferent activity of cardiac
origin (dogs, monkeys)
R01HL-20400-03 Diabetic neuropathy and peripheral
vascular diseases (human, hamsters)
NERVOUS DISORDERS AUTONOMIC (GENERAL)
SEE ALSO CONGENITAL ABNORMALITIES, NEUROLOGICAL,
DYSAUTONOMIA FAMILIAL
P01HL-14388-07 0164 Regulation of the circulation in
pathological states - Hyperkinetic heart syndrome (human)
ROlHL-15677-06 Autonomic nervous system function in
bronchial asthma (human, guinea pig, rabbit)
ROlHL-16784-03 Lung tissue and water volume (human,
dogs)
ROlHL-19467-03 Regulation of blood pressure (rats, dogs)
ROlHL-20400-03 Diabetic neuropathy and peripheral
vascular diseases (human, hamsters)
ROlHL-22581-02 Neurocirculatory control in diabetes
mellitus (human)
NERVOUS DISORDERS CENTRAL (GENERAL)
SEE ALSO BRAIN DISORDERS
SEE ALSO CARDIOVASCULAR DISORDERS, HYPERTENSION
(SYSTEMIC), NEUROGENIC HYPERTENSION
SEE ALSO NERVOUS DISORDERS, MYELINOPATHIES
(GENERAL)
SEE ALSO NEUROMOTOR DISORDERS
P01HL08899-14 0032 Tolerance to respiratory gases in
health and disease - Effects of high oxygen pressures upon
respiratory control
POlHL-14388-07 0179 Regulation of the circulation in
pathological states - Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
R01HL-15781-06 Guided vascular obliteration of CNS
vascular lesions (human)
R01HL-20724-01 Behavioral consequences of hypertension
(human)
NERVOUS DISORDERS CENTRAL, MAREK'S
DISEASE
** ROlHL-19381-03 Pathogenesis of viral induced
atherosclerosis (human, chicken)
NERVOUS DISORDERS CENTRAL, MENINGITIS
BACTERIAL
SEE ALSO BACTERIA. NEISSERIACEAE. NEISSERIA
MENINGITIDIS*
** POlHL-06350-17 0019 Hemostasis research program
project - Microcirculation (human, rats, rabbits)
P60HL-1516207 0021 Comprehensive sickle cell center •
Pneumococcal vaccine in sickle cell disease (children)
ROlHL-203 14-02 Host defense against S pheumoniae in
sickle cell disease (human)
P60HL-20985-01 0002 Northern California sickle cell
center - Immunization with polyvalent pneumococcal
polysaccharide vaccine (human)
NERVOUS DISORDERS CHEMOTHERAPY
SEE ALSO NEUROMOTOR DISORDERS CHEMOTHERAPY
SEE ALSO NEUROPHARMACOLOGY
ROlHL-22258-01 New aspects of pharmacology related to
carbonic anhydrase
NERVOUS DISORDERS DIAGNOSIS (INCL
EXAMS)*
SEE ALSO BRAIN ELECTRICAL ACTIVITY
SEE ALSO BRAIN MAPPING
SEE ALSO NERVOUS SYSTEM CENTRAL. SPINAL CORD
MAPPING
SEE ALSO NEUROMOTOR DISORDERS DIAGNOSIS (INCL
EXAMS)*
SEE ALSO NEUROPSYCHOLOGICAL TESTS*
POlHL-04664-18 0008 Cardiovascular and lung dynamics
- Micrographic video imaging technique
NER
" P50HL-14218-07 0015 Pulmonary SCOR -Newborn lung
center ■ Long term follow-up of infants surviving RDS -
Neurological outcome (human)
NERVOUS DISORDERS EPIDEMIOLOGY
ROlHL-19839-09 Factors in youth predisposing to chronic
diseases (former college students)
** R01HL-20724-01 Behavioral consequences of hypertension
(human)
NERVOUS DISORDERS PERIPHERAL
SEE ALSO CARBOHYDRATES METABOLISM DISORDERS.
DIABETIC NEUROPATHIES
ROlHL-20400-03 Diabetic neuropathy and peripheral
vascular diseases (human, hamsters)
NERVOUS NEOPLASMS
SEE NEOPUSMS OF NERVOUS SYSTEM
NERVOUS SYSTEM
SEE ALSO BRAIN
SEE ALSO SENSE ORGANS
R01HL15231-05 Mechanisms of hemodynamic changes
during digestion (dogs)
NERVOUS SYSTEM, AFFERENT NERVES
R01HL05883-18 0004 Reflex control of resistance and
capacitance vessels Left ventricular receptors with
nonmedullated vagal afferents (cat's)
ROlHL-05883 18 0005 Reflex control of resistance and
capacitance vessels - Differential blockade of medullated
and nonmedullated vagal afferents in the cat
ROlHL-05883-18 0006 Reflex control of resistance and
capacitance vessels - Cardiopulmonary vagal afferents in
the conscious dog
** POlHL-0628518 0180 Cardiovascular-respiratory
physiology and biochemistry - Vagal C-fibers and their
influence on visceral and somatic function (animals)
POlHL-06285-18 0182 Cardiovascular-respiratory
physiology and biochemistry - Structure and function of
vascular chemoreceptors (cats, rats)
P01HL06296-18 0007 Cardiovascular and pulmonary
adaptation to stress - Cardiovascular control during
isometric exercise (cats)
** POlHL-08682-15 0018 Regulation of the cardiovascular
system - Functional implications of cardiac afferent nerves
(dogs)
POlHL-08682-15 0022 Regulation of the cardiovascular
system Blood pressure responses and preganglionic
sympathetic outflow (cat)
POlHL-08805-15 0045 Regulation of ventilation and
pulmonary circulation - Integrated description of
neurochemical respiratory control system
POlHL-1 1310-12 0087 Mechanisms of cardiovascular
disease Electrophysiology and electropharmacology of the
heart (dogs)
Evaluation of left ventricular function
Neural control of blood volume (monkeys.
ROlHL-12415-10
(dogs, rabbits)
R01HL-13427-09
dogs)
ROlHL-13888-15 Regulation of respiration
POlHL-14388-07 0155 Regulation of the circulation in
pathological states - Cardiopulmonary afferent activity.
carotid chemo-baroreceptor reflexes
POlHL-14388-07 0179 Regulation of the circulation in
pathological states Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
POlHL-14388-07 0180 Regulation of the circulation in
pathological states - Regulation of cerebral blood flow
(dogs, monkeys)
P01HL14388-07 0185
pathological states -
rabbits, dogs)
POlHL-14388-07 0195
pathological states
Regulation of the circulation in
Reflex control of venous tone (human.
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
**0nented significantly to above subject.
M Grant has subprojects describing specific research aspects
See Appendix for investigator's name and grant number
Regulation of the circulation in
General review of potential
pathophysiologic factors in spontaneous hypertension
POlHL-14388-07 0213 Regulation of the circulation in
pathological states Regulation of the heart and peripheral
circulation in heart failure
ROlHL-16066-05 Studies on neurogenic control of the
circulation (human, dogs)
R01HL16511-04 Sympathetic afferent activity of cardiac
origin (dogs, monkeys)
ROlHL-16648-16 Integrated control of cardiovascular
activity (cats)
ROlHL-17715-04 Respiratory muscle afferents in
respiratory control (cats)
ROlHL-17800-04 Pulmonary reflexes -Central pathways
(cats, dogs, rabbits)
ROlHL-18371-03 Pulmonary hypertension and ventilation
pathophysiology (dogs)
ROlHL-18994-03 Substance P-Occurrence, pharmacology
and physiology (mammals non-human, human)
R01HL-19G48-03 Structure of baroreceptors in
hypertension (rats)
P50HL-19156-02 0005 Pulmonary SCOR -Chronic diseases
of airways - Vagal receptors in the airway-Epithelial injury
and antigen (dog, cat, rabbit)
POlHL-1973702 0011 Cellular and molecular aspects of
respiratory physiology - Chemical and metabolic factors on
peripheral chemoreceptor activity (cats)
ROlHL-19827-02 Role of the upper airways in the control
of breathing (human, cats, dogs)
(contd)
i^^sss;^.^
NK
ROIHI I999!>02 Stnsofy transduction in cardiac
machanorectptors (catso trogs. rats)
R01Hl20b48 02 Innervation of tK« iun| (rats, monkeys)
ROIHL 20800 W Neural basis ot respiratory and
vasomotor activity (cats)
ROIHL 20864 01 Postnatal maturation ot cardiovascular
regulatory system (minipig)
R23HI 21042 01 Cardiopulmonary rellexes and then
anatomical basis (dogs)
ROIHL 21158 02 Cardiac receptors with vagal C tiber
atlerents (cats)
ROIHL'21351 02 Renal and vascular control by
sympathetic ganglia (animals)
R01H12143602 Autonomic control ot renal (unction
(cats)
R23HL 2224502
receptors (rats)
ROIHL 2248201
excretion (dogs)
ROIHL 2259401
failure (dogs)
' R01HL2273201
Functional characteristics ol atrial
Circulatory hemodynamics and sodium
Retlex control ot the circulation in heart
Central organization of cardiac afferent
nerves (cats, monkeys)
ROIHL 2291001 Control ot breathing pattern in health
and disease (human, animals)
NERVOUS SYSTEM, AFFERENT NERVES,
CUTANEOUS SENSORY NERVES
POlHL-08899 14 0078 Tolerance to respiratory gases in
health and disease Isobaric gas counterdiffusion-Sensory.
cutaneous and systemic function (animals)
NERVOUS SYSTEM, AFFERENT NERVES,
SOMATIC AFFERENT NERVES
P01HL0868215 0024 Regulation of the cardiovascular
system • Morphology of the spinal sympathetic system (cat)
NERVOUS SYSTEM, AFFERENT NERVES,
VISCERAL AFFERENT NERVES
" PC1HL0628518 0180 Cardiovascular-respiratory
physiology and biochemistry - Vagal C-fibers and their
influence on visceral and somatic function (animals)
P01HL0868215 0024 Regulation of the cardiovascular
system - Morphology of the spinal sympathetic system (cat)
*• R23HL-22669-01 Cardiovascular effects from visceral
atferents (dogs)
ROlHL-22732-01 Central organization of cardiac afferent
nerves (cats, monkeys)
NERVOUS SYSTEM, CRANIAL NERVES,
LARYNGEAL NERVES
P50HL14214-07 0027 Newborn lung center for hyaline
membrane disease ■ Oral-laryngeal chemoreceptors and
respiratory failure in newborns (human, sheep)
ROlHL-1982702 Role of the upper airways in the control
of breathing (human, cats, dogs)
NERVOUS SYSTEM, CRANIAL NERVES,
TRIGEMINAL NERVE
P50HL-14214-07 0029 Newborn lung center for hyaline
membrane disease ■ The diving reflex-Perinatal asphyxia,
pulmonary ischemia and HMD (sheep)
NERVOUS SYSTEM, CRANIAL NERVES, VAGUS
R01HL02888-22 Interrelationships of circulation and
respiration (opossum, cats)
ROlHL-05883-18 0004 Reflex control of resistance and
capacitance vessels - Left ventricular receptors with
nonmedullated vagal afferents (cats)
R01HL0588318 0005 Reflex control of resistance and
capacitance vessels ■ Differential blockade of medullated
and nonmedullated vagal afferents in the cat
ROlHL-05883-18 0006 Reflex control of resistance and
capacitance vessels - Cardiopulmonary vagal afferents in
the conscious dog
*• POlHL-06285-18 0180 Cardiovascular-respiratory
physiology and biochemistry - Vagal C-fibers and their
influence on visceral and somatic function (animals)
** P01HL0628518 0181 Cardiovascular-respiratory
physiology and biochemistry - Regulation of resprration -
Role of vagus nerve (dogs)
POlHL-05285-18 0188 Cardiovascular-respiratory
physiology and biochemistry - Physiology and pharmacology
in regulation of ainways-hyperirritability (animals)
P01HL06285-18 0189 Cardiovascular-respiratory
physiology and biochemistry Mucociliary clearance (cats,
dogs)
ROlHL-07776-15 Sudden death and cardiac arrhythmias
(human, dogs, cats)
** POlHL-08682 15 0015 Regulation of the cardiovascular
system ■ Projection of autonomic nerves onto the heart
(dog)
P01HL-08682-15 0016 Regulation of the cardiovascular
system - Shifting cardiac pacemakers and AV nodal
activation (dog)
POlHL-0868215 0017 Regulation of the cardiovascular
system • Neurally induced cardiac dysrhythmias (dog)
** R01HL10951-11 Neural control of the heart (dogs, rats)
ROlHL-12415-10 Evaluation of left ventricular function
(dogs, rabbits)
POlHL-12738-10 0035 Physiologic pharmacology and its
clinical applications - Function and dysfunction of the
sinoatrial node (human)
369
ROIHL 13427 09 Neural control ot blood volume (monkeys,
dogs)
ROIHI 13888 15 Regulation ot respiration
P50HI 14214 07 0022 Newborn lung center tor hyaline
membrane disease Functional integrity ol surfactant
system Hyaline membrane disease (lamb, rat)
POIHL 1438807 0155 Regulation ol the circulation in
pathological states Cardiopulmonary afferent activity,
carotid chemo baroreceptor rellexes
NER
POIHL 14388 07 0185
pathological states
rabbits, dogs)
POIHL 1438807 0213
pathological states
Regulation of the circulation in
Retlex control ot venous tone (human.
Regulation of the circulation in
Regulation ol the heart and peripheral
circulation in heart failure
POIHL 1498507 0004 Adaptation to hypoxia Control ol
breathing in respiratory failure (human, dogs)
POIHL 14985 07 0009 Adaptation to hypoxia Influence
ol chemosensitivity on control ol breathing during sleep
(human, dogs)
P50HL 15061 07 0005 Response ol lung to iniury Airway
smooth muscle in health and disease (dogs, guinea pigs)
ROIHL 1575806 Catecholamine release in the heart
(dogs)
ROIHL 16066 05 Studies on neurogenic control of the
circulation (human, dogs)
ROIHL 1651 104 Sympathetic afferent activity ol cardiac
origin (dogs, monkeys)
ROlHL-1665706 Innervatron of coronary arteries and heart
(rats)
ROIHL 1731404 Effects of anesthesia and loading on
respiration (human, cats)
ROlHL-17799-02 The presence and significance of heart
acetylcholine (cats)
ROIHL 1780004 Pulmonary reflexes -Central pathways
(cats. dogs, rabbits)
ROIHL 1879604 Experimental cardiac arrhythmias (dogs)
POlHL-1897403 0001 Experimental neurogenic
hypertension program Central neural systems regulating
arterial pressure (rabbits)
ROlHL-1907603 Vagal control of heart rate-A biophysical
model (rabbits)
P50HL191 56-02 0004 Pulmonary SCOR -Chronic drseases
of airways Interactions between mast cells, mediators
and nerves in canine asthma
P50HL- 19 156-02 0005 Pulmonary SCOR-Chronic diseases
of airways - Vagal receptors in the airway -Epithelial injury
and antigen (dog, cat, rabbit)
P50HL191 70-02 0003 Harvard pulmonary SCOR-Chronic
diseases of the airways ■ Mechanisms of bronchial
reactivity to acute and chronic airway challenge (dog)
P50HL-19185-02 0003 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Factors affecting formation
and release of pulmonary surfactant in fetal lambs
R01HL19487-03 Cardiac actions of digitalis (dogs, cats)
ROlHL-20328-01 Noninvasive assessment ol autonomic
cardiac control (dogs)
ROlHL-20572-02 0008 Hemodynamic relations to
metabolism in hypertension Role of nervous system in
hemodynamic function
R23HL-21042-01 Cardiopulmonary reflexes and their
anatomical basis (dogs)
ROlHL-21 158-02
afferents (cats)
R23HL-22245-02
receptors (rats)
ROlHL-22482-01
excretion (dogs)
ROlHL-22484-01
excitation (dogs)
R23HL-22728-01
R23HL-22775-01
Cardiac receptors with vagal Cfiber
Functional characteristics of atrial
Circulatory hemodynamics and sodium
Neural control of cardiac conduction and
Neural control of renin secretion (dogs)
Muscarinic receptors in the developing
heart (chick embryo)
ROlHL-2291001 Control of breathing pattern in health
and disease (human, animals)
R23HL-2292001 Dynamic airway behavior (dogs)
ROlHL-22924-01 The airway mucosal barrier (guinea pigs)
NERVOUS SYSTEM, EFFERENT NERVES
SEE ALSO NERVOUS SYSTEM, NEUROEFFECTORS
** POlHL-06285-18 0188 Cardiovascular-respiratory
physiology and biochemistry - Physiology and pharmacology
in regulation of airwayshyperirritability (animals)
P01HL08805-15 0045 Regulation of ventilation and
pulmonary circulation - Integrated description of
neurochemical respiratory control system
P01HL14388-07 0179 Regulation of the circulation in
pathological states - Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
POlHL-14388-07 0208 Regulation of the circulation in
pathological states - Baroreceptor reflex function in normal
and hypertensive man
P01HL14388-07 0229 Regulation of the circulation in
pathological states - Mechanism of postural hypotension
(human)
ROlHL-19048-03 Structure of baroreceptors in
hypertension (rats)
ROlHL-201 22-02 Operational mechanisms of airway
receptors (dogs, pigs)
ROlHL-22667-01 Mechanisms of baroreceptor adaptation
in hypertension (dogs)
NERVOUS SYSTEM, GANGLIA
SFE AISONFRVOIJS SYMIM CARAGANGI lA
SEE ALSO NfRVODS SYMIM AIJIONOMIC, AUTONOMIC
GANGI lA
POIHl 1438807 0202 Regulation ol the circulation m
pathological states Development of hypertension in
spontaneously hypertensive lals
POIHL 14388 07 0211 Regulation of the circulation in
pathological stales Choline acetyltranslerase activity
(rats)
POIHL 1438807 0213
pathological states
Regulation ol the circulation in
Regulation of the heart and peripheral
circulation in heart lailure
ROIHL 16315 05 Analysis ol mteraction between CNS
vasomotor systems (cats, rats)
R23HI 2104201 Cardiopulmonary rellexes and their
anatomical basis (dogs)
R23HL 21914 01 Studies of vasomotor control (rats)
R23HL 2277501 Muscarinic receptors in the developing
heart (chick embryo)
NERVOUS SYSTEM, GANGLIA, PREGANGLIONIC
FIBERS
POIHL 08682 15 0022 Regulation of the cardiovascular
system Blood pressure responses and preganglionic
sympathetic outllow (cat)
POIHL 08682 15 0024 Regulation ol the cardiovascular
system Morphology ol the spinal sympathetic system (cat)
** POlHL-0868215 0025 Regulation ol the cardiovascular
system Physiology ol preganglionic cell bodies (cat)
NERVOUS SYSTEM, MYELINATION
P01HL08214-15 0027 Chemical and biological properties
ol lipids Biological lunctions diol lipids (swine, rats.
plants)
NERVOUS SYSTEM, NERVE ENDINGS (GENERAL)
POlHL-06285-18 0180 Cardiovascular respiratory
physiology and biochemistry - Vagal Clibers and their
inlluence on visceral and somatic lunction (animals)
R01HL18185-04 Cardiac glycosides and diuretics-Role of
NaO pump (dogs)
ROlHL-18340-04 Electron microscopy of the
juxtaglomerular apparatus (rats)
ROlHL-19379-03 Characterization of small-granule cells in
the lung (mammals)
•* ROlHL-2 1099-02 Subcellular changes of blood vessels in
hypertension (rats)
NERVOUS SYSTEM, NERVE ENDINGS, SYNAPSES
POlHL-06285-18 0182 Cardiovascular-respiratory
physiology and biochemistry - Structure and function of
vascular chemoreceptors (cats, rats)
** POlHL-0789615 0052 Environmental biomedical research
program - Effects of hypoxia on cerebral function
POlHL-08682-15 0025 Regulation of the cardiovascular
system - Physiology of preganglionic cell bodies (cat)
POlHL-1438807 0194 Regulation of the circulation in
pathological states - Dopamine-betahydroxylase localization
and release in hypertension
POlHL-14388-07 0211 Regulation of the circulation in
pathological states ■ Choline acetyltransferase activity
(rats)
POlHL-161 17-05 0006 Ion movements and membranes in
cardiovascular control - Neuroreceptors and cellular
excitation (fish)
** ROlHL-17370-03 Synaptic chemistry and cardioregulation
in Limulus
ROlHL-20548-02
ROlHL-21195-02
receptors (frogs)
ROlHL-21351-02 Renal and vascular control by
sympathetic ganglia (animals)
** ROlHL-22170-01 Factors influencing transmission at
adrenergic synpases
ROlHL-22767-01 Model system for cardiac action
potentials (squid, axons)
NERVOUS SYSTEM, NERVE ENDINGS, SYNAPTIC
VESICLES
POlHL-06285-18 0182 Cardiovascular-respiratory
physiology and biochemistry - Structure and function of
vascular chemoreceptors (cats, rats)
ROlHL-08359-14 Morphopharmacology of vascular
adrenergic transmission (rabbits, rats)
ROlHL-20446-02 Autonomic neuropathy in diabetic mice
(also rats)
NERVOUS SYSTEM, NERVE ENDINGS,
SYNAPTOSOMES
ROlHL-08359-14 Morphopharmacology of vascular
adrenergic transmission (rabbits, rats)
POlHL-1131012 0097 Mechanisms of cardiovascular
disease - Structural-functional relationships of neuronal
differential alloantigens (mice)
** POIHLI 131012 0098 Mechanisms of cardiovascular
disease - Protein chemistry of thy-1 and related
synaptosomal proteins (mice)
** P01HL11310-12 0099 Mechanisms of cardiovascular
disease Carbohydrate chemistry of thy-1 and related
synaptosomal proteins
ROlHL-16436-04 Role ol calcium and thyroxine in heart
function (rats)
(contd)
Innervation of the lung (rats, monkeys)
Innervation of the heart-Acetylcholine
•Excludes routine methodotogy OR covers only general projects which preclude indexing at the specific level.
**0riented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
NER
NERVOUS SYSTEM, NERVES (GENERAL)
POlHL-06312'17 0033 Surgical cardiology ■ Studies in
ciyopreservations (rats)
NERVOUS SYSTEM, NERVES, INNERVATION
(GENERAL)
SEE ALSO NERVOUS SYSTEM AUTONOMIC, HEART
INNERVATION
R01HL05949-18 Biochemistry of muscle contractior) (rats,
rabbits)
P01HL-0e83517 0043 Cardiovascular disease - Left
atrial receptor activity by the sympathetic nervous system
(dogs)
R01HL-0g696'l5 0020 Orthotopic heart transplantation -
Complete cardiopulmonary transplantation (dogs)
P01HL-08g05-l5 0039 Regulation of ventilation and
pulmonary circulation - Carotid body (cats)
POlHL'12738-10 0135 Physiologic pharmacology and its
clinical applications - Myocardial cells in tissue culture
(rats, chich embryo)
R01HL13339-08 Pharmacology of developing cardiac
tissues (chick embryo)
P50HL-15061'07 0005 Response of lung to injury - Airvnay
smooth muscle in health and disease (dogs, guinea pigs)
ROIHL- 15805-06 Cerebral arterial tone and reactivity
(rabbits)
ROlHL-16768-04 The sympathetic nervous system and the
arterial wall (rabbits, pigeons)
ROlHL-1735804 Ventilatory adjustments for optimal
oxygenation (dogs, rats)
ROlHL-17596-03 Leukocyteendothelial interactions (rats)
R01HL18340-04 Electron microscopy of the
juxtaglomerular apparatus (rats)
POlHL-18974-03 0008 Experimental neurogenic
hypertension program - Monoamines and hypertension
(rats)
ROlHL'19048-03 Structure of baroreceptors in
hypertension (rats)
R01HL19275-03 Characterization of collateral blood
vessels (dogs)
ROlHL-19379-03 Characterization of small-granule cells in
the lung (mammals)
ROlHL-20400-03 Diabetic neuropathy and peripheral
vascular diseases (human, hamsters)
ROlHL-20446-02 Autonomic neuropathy in diabetic mice
(also rats)
** ROlHL-20548-02 Innervation of the lung (rats, monkeys)
** POlHL-2058101 0001 Vascular neuroeffecfor
mechanisms in heaKh and disease - Vascular neuroeffecfor
mechanism (rabbits)
" POlHL-20581-01 0002 Vascular neuroeffector
mechanisms in health and disease - Trophic interaction
between adrenergic nerves and vascular smooth muscle
** POlHL-20581-01 0003 Vascular neuroeffector
mechanisms in health and disease - Cerebrovascular
neuroeffector characteristics (animals)
•* POlHL-20581-01 0004 Vascular neuroeffector
mechanisms in health and disease - Neuroeffector
characteristics of mesenteric and pulmonary blood vessels
(rabbits)
" POlHL-20581-01 0005 Vascular neuroeffector
mechanisms in health and disease - Changes in the
neuroeffector mechanism in hypertension (rabbits)
R23HL-21042-01 Cardiopulmonary reflexes and their
anatomical basis (dogs)
R23HL-22728-01 Neural control of renin secretion (dogs)
** ROlHL-2278401 Ductus arteriosus closure-An arterial
lesion model (rabbits)
ROlHL-23604-01 Hepatic microvascular regulatory
mechanisms (rat)
NERVOUS SYSTEM, NEUROEFFECTORS
SEE ALSO NEUROMOTOR SYSTEM, NEUROMUSCULAR
JUNCTION
** ROlHL-05883-18 0001 Reflex control of resistance and
capacitance vessels - Naturally occurring vasoactive
substances and the vascular neuroeffectors (dog)
ROlHL-08359-14 Morphopharmacology of vascular
adrenergic transmission (rabbits, rats)
P01HL-08e82-15 0025 Regulation of the cardiovascular
system - Physiology of preganglionic cell bodies (cat)
ROlHL-20548-02 Innervation of the lung (rats, monkeys)
NERVOUS SYSTEM, NEUROGENESIS
SEE ALSO NERVOUS SYSTEM REGENERATION
ROlHL-01755-25 Fetal and neonatal cardiovascular
function (sheep)
POlHL-1 1310-12 0097 Mechanisms of cardiovascular
disease - Structural-functional relationships of neuronal
differential alloantigens (mice)
P01HL-I2738-10 0135 Physiologic pharmacology and its
clinical applications - Myocardial cells in tissue culture
(rats, chick embryo)
** ROlHL-18657-03 Pharmacologic studies on neurogenic
digitalis effects (human, cats, dogs)
ROlHL-20548-02 Innervation of the lung (rats, monkeys)
•* ROlHL-22226-01 Autonomic nervous elements in the
developing heart (rabbits)
NERVOUS SYSTEM, NEUROGLIA
R01HL-18351-03 Brain metabolism, acid-base balance.
and respiration
370
ROlHL-22239-01 The molecular basis of electrical
excitability (chick embryos, rats)
NERVOUS SYSTEM, NEURONS
SEE ALSO BRAIN. CEREBELUR CORTEX, PURKINJE CELLS
SEE ALSO BRAIN CELLS
SEE ALSO NERVOUS SYSTEM, NERVE ENDINGS (GENERAL)
SEE ALSO NEUROMOTOR SYSTEM, MOTOR NEURONS
ROlHL-03290-22 Controls of cardiac and vascular smooth
muscles (cats, rats, dogs)
POlHL-06285-18 0182 Cardiovascular-respiratory
physiology and biochemistry - Structure and function of
vascular chemoreceptors (cats, rats)
" POlHL-11310-12 0097 Mechanisms of cardiovascular
disease - Structural-functional relationships of neuronal
differential alloantigens (mice)
ROlHL-13187-09 Central neural control of cardiovascular
function (cats)
POlHL-14388-07 0212 Regulation of the circulation in
pathological states - Role of dopamine in autonomic
activity
ROlHL-16315-05 Analysis of interaction between CNS
vasomotor systems (cats, rats)
** ROlHL-16648-16 Integrated control of cardiovascular
activity (cats)
** POlHL-16878-05 0003 Control of ventilation in health
and disease - Brain stem respiratory neurons in response
mechanical/chemical loading (animal)
** POlHL-16878-05 0004 Control of ventilation in health
and disease - Neurotransmitters in the respiratory system
(cats)
P50HL-1 7648-04 0028 Study of ischemic heart disease -
Electrophysiology of sympathetic innervation in tissue
culture
ROlHL-17800-04 Pulmonary reflexes-Central pathways
(cats, dogs, rabbits)
ROlHL-18351-03 Brain metabolism, acid-base balance.
and respiration
POlHL-18974-03 0012 Experimental neurogenic
hypertension program - Immunohistochemistry of central
monoamine neurons (rats)
" ROlHL-20254-02 Probes of heart and nerve membranes -
Fluorescent dyes
ROlHL-20800-17 Neural basis of respiratory and
vasomotor activity (cats)
ROlHL-22418-01 Neural control of cardiorespiratory
function (cats)
NERVOUS SYSTEM, NEURONS, AXONS
ROlHL-01974-24 Ion-pump in the erythrocyte (rabbits.
guinea pigs)
POlHL-14388-07 9003 Regulation of the circulation in
pathological states - Electron probe projects
R23HL-2121301 A model for calcium homeostasis in
excitable tissue (marine worms)
ROlHL-22201-01 Pharmacology and chemistry of
nudibranch toxins (guinea pigs, rats, mice)
R23HL-22245-02 Functional characteristics of atrial
receptors (rats)
ROlHL-22767-01 Model system for cardiac action
potentials (squid, axons)
NERVOUS SYSTEM, NEURONS, AXOPLASMIC
FLOW
ROlHL-20446-02 Autonomic neuropathy in diabetic mice
(also rats)
ROlHL-21860-18 Factors influencing responses to
adrenergic drugs (guinea pigs, rats, cats)
NERVOUS SYSTEM, NEURONS, NEUROFIBRILS
POlKL-04664-18 0008 Cardiovascular and lung dynamics
- Micrographic video imaging technique
ROlHL-05883-18 0005 Reflex control of resistance and
capacitance vessels - Differential blockade of medullated
and non-medullated vagal afferents in the cat
ROlHL-05883-18 0006 Reflex control of resistance and
capacitance vessels - Cardiopulmonary vagal afferents in
the conscious dog
POlHL-0628518 0180 Cardiovascular-respiratory
physiology and biochemistry - Vagal C-fibers and their
influence on visceral and somatic function (animals)
NERVOUS SYSTEM, NEURONS, NEUROPIL
POlHL-063 14-17 0052 Immunologic mechanisms in
cardiovascular disease - Role of cyclic nucleotides in
neutrophil function (human)
NERVOUS SYSTEM, PARAGANGLIA
SEE ALSO ADRENAL MEDULLA
POlHL-06285-18 0182 Cardiovascular-respiratory
physiology and biochemistry - Structure and function of
vascular chemoreceptors (cats, rats)
POlHL-14388-07 0212 Regulation of the circulation in
pathological states - Role of dopamine in autonomic
activity
R01HL-Igl48-04 Adrenal catecholamine secretion
NERVOUS SYSTEM, PARAGANGLIA, AORTIC
BODY
** P01HL10342-13 0026 The integrated function of
respiration and circulation - Control of respiration-
Characterization of the aortic body (cats)
NER
POlHL-10342-13 0027 The integrated function of
respiration and circulation - Control of respiration-
Cardiovascular adjustment to hypoxia and carbon monoxide
NERVOUS SYSTEM, PARAGANGLIA, CAROTID
BODY
ROlHL-02888-22 Interrelationships of circulation and
respiration (opossum, cats)
** POlHL-06285-18 0182 Cardiovascular-respiratory
physiology and biochemistry - Structure and function of
vascular chemoreceptors (cats, rats)
** POlHL-08805-15 0039 Regulation of ventilation and
pulmonary circulation - Carotid body (cats)
" POIHL- 10342 13 0011 The integrated function of
respiration and circulation - Control of respiration 1 -
Peripheral chemoreceptor studies (cats)
POlHL-1167811 0009 Cardiovascular dynamics and their
control Control of respiration (cat. human)
ROlHL-11907-08 Mechanisms of physiological responses
to exercise (human, dogs)
ROlHL-12564-09
(human, dog)
ROlHL-13134-07
Control of respiration and blood gases
Mechanism of chemoreceptor discharge
(cats)
ROIHL 14967-06 Chemoreceptor function in dynamic
ventilatory control (human, dogs)
" R01HL15659-05 Dynamic isolation studies of control of
respiration (human)
ROlHL-16828-04 Gradient and transport of oxygen in
tissue and organs (mammals)
ROlHL-19410-03 Dynamic interrelations underlying
exercise hyperpnea (human)
ROlHL-20574-03 Brain stem integration of chemoreceptor
activity (cats)
R01HL-2II72-02 Regional oxygen consumption of heart
and other organs (animals)
NERVOUS SYSTEM, PERIPHERAL NERVES
(GENERAL)
SEE ALSO NERVOUS DISORDERS PERIPHERAL
" POlHL-08805-15 0046 Regulation of ventilation and
pulmonary circulation - Sites and modes of interaction of
peripheral and central chemoreceptors
** P01HL13480-09 0026 Cardiac electrophysiology - Neural
influences on cardiac electrophysiology and contraction
(dog. cat)
POlHL-14388-07 0203 Regulation of the circulation in
pathological states - Activation of sympathetic nervous
systems in spontaneously hyperactive rats
ROlHL-17314-04 Effects of anesthesia and loading on
respiration (human, cats)
R01HL-I8601-01
adenosine (rats)
ROlHL-19257-03
Regulation of neurotransmitter release by
Cardiovascular adjustment to behavioral
'EicludK niiitine melhadok>gy OR cavers only general projects which preclude indexing at the specific level.
**0!i6Pt»<( ^ii nificantly to alxwe subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
stress (dog)
ROlHL-19379-03 Characterization of small-granule cells in
the lung (mammals)
ROlHL-20381-03 Long-term study of diabetic vascular
disease (human)
ROlHL-22170-01 Factors influencing transmission at
adrenergic synpases
ROIHL 23601-01 Early hypoxia and development of
respiratory control
NERVOUS SYSTEM, SPINAL NERVES
** ROlHL-22732-01 Central organization of cardiac afferent
nerves (cats, monkeys)
NERVOUS SYSTEM, SPINAL NERVES, PHRENIC
NERVE
ROlHL-04651-19 Remote stimulation by radio-frequency
transmission (dogs, human)
** POlHL-08682-15 0037 Regulation of the cardiovascular
system - Central nervous regulation of cardiopulmonary
mechanisms (cats)
ROlHL-08696-15 0020 Orthotopic heart transplantation -
Complete cardiopulmonary transplantation (dogs)
POlHL-08805-15 0044 Regulation of ventilation and
pulmonary circulation - Neurochemical interactions in
respiratory control (human, dogs, goats)
POlHL-08805-15 0045 Regulation of ventilation and
pulmonary circulation - Integrated description of
neurochemical respiratory control system
POlHL-08805-15 0047 Regulation of ventilation and
pulmonary circulation - Extracranial metabolic control of
ventilation (dogs, goals)
ROlHL-18007-05 Neural mechanisms controling motor act
of breathing (cats, human)
** ROlHL-22844-01 Phrenic nerve pacing-Noninvasive
diaphragm analysis (human, dogs)
ROlHL-23985-01 Role of the diaphragm in regional lung
mechanics (dogs)
NERVOUS SYSTEM AUTONOMIC
SEE ALSO NERVOUS DISORDERS AUTONOMIC (GENERAL)
R01HL-02953-17 Autonomic and cardiovascular
pharmacology (rats, rabbits, dogs, guinea pigs)
ROlHL-04457-20 Cellular aspects of active transport (fish.
rabbits, anurans. turtles)
ROlHL-06143-18 Response of the totally denervated heart
to exercise (dogs)
(contd)
is^ii^s^^^Mift
NiR
POIHL 0628b 18 0125 Cardiovascular respiiatory
physiology and biochemistry Myocardial lunction in the
letal and neonatal lamb
PO1H10628S 18 0188 Cardiovascular respiratory
physiology and biochemistry Physiology and pharmacology
in regulation ol airways hyperirritability (animals)
P01Hl'0628S 18 0189 Cardiovascular respiratory
physiology and biochemistry Mucociliary clearance (cats,
dogs)
POIHL 06308 18 0037 Mechanisms and therapy ol
circulatory disease Electrophysiology. blood How. and ANS
in ventricular fibrillation (dogs)
P01HL06308 18 0039 Mechanisms and therapy ol
circulatory disease ANS in regulation ol electrophysiology
Role of cyclic nulceotides (animals)
P01HL06312 17 0028 Surgical cardiology Coronary How
in the transplanted denervated heart (dogs)
ROIHI'07047 16 Comparative study ot cardiac conduction
system (human, birds, mammals)
R01HL'086S9 14 Myocardial performance and metabolism
in the newborn (sheep)
POIHL 10342 13 0028 The integrated lunction ol
respiration and circulation Mediator release,
hemodynamics and respiratory function m anaphylaxis
(dogs)
R01HL1241510 Evaluation of left ventricular lunction
(dogs, rabbits)
R01HL12607 10
dogs, rats)
ROIHI 1282708
rats)
P01HL'13 108-09 0017 CHnical heart transplantation -
Electrophysiology of the transplanted denervated human
heart
' P01HL1310809 0019 Clinical heart transplantation ■
EWect of autonomic nervous system on arrhythmias
(human)
' P01HL1310809 0020 Clinical heart transplantation -
Autonomic neural studies in the denervated heart (human)
' P01HL13108-09 0021 Clinical heart transplantation -
Autonomic reflex regulation of ventricular function (human)
' ROlHL-1333908 Pharmacology of developing cardiac
tissues (chick embryo)
R01HL-13e34-08 Renal hypertension in pregnancy (sheep)
' PO1HL14388-07 0211 Regulation ol the circulation in
pathological states Choline acetyltransferase activity
(rats)
' P01HL14388-07 0212
pathological states -
activity
■ P01HL14388-07 0234
pathological states -
Dynamics of pulsatile blood flow (human.
Regulation of sodium excretion (dogs.
Regulation of the circulation in
Role of dopamine in autonomic
Regulation ol the circulation in
Elfects of antiarrhythmic drugs on the
autonomic system (dogs)
ROlHL-14717-06 Hemodynamics and heart structure-
Ventricular overload (dogs)
R01HL15416-06 Cardiovascular control in normal and
disease states (dogs, baboons)
ROlHL-16648-16 Integrated control ol cardiovascular
activity (cats)
R01HL-16656-06 Left ventricular function in exercise
(dogs)
P01HL17382-05 0002 Chemical mediators of acute
pulmonary disorders - Chemical mediators and respiratory
mechanics in guinea pigs
ROlHL-1797004 Vascular eticcts ol inhibitory behavioral
adaptations (dogs)
ROlHL-18601-01 Regulation ot neurotransmitter release by
adenosine (rats)
P50HL-I9156-02 0004 Pulmonary SCOR -Chronic diseases
of airways - Interactions between mast cells, mediators
and nerves in canine asthma
ROlHL-19343-03 Behavioral influences on cardiac
contractility (monkeys)
ROlHL-20328-01 Noninvasive assessment ol autonomic
cardiac control (dogs)
ROlHL-20366-03 Protein turnover and amino acid
transport by lung (rats)
ROlHL-20655-02 Autonomic predictors ol hypertension in
children
ROlHL-20678-02 Cardiovascular adaptation to stress in
disease states (dogs)
R01HL-2I436-02 Autonomic control of renal lunction
(cats)
ROlHL-21451-01 Control ol circulation during heat stress
and lever (baboon)
POlHL-21584-02 0005 Respiratory mechanics in normal
and abnormal states - Regulation and behavior of airway
smooth muscle (human, animals)
ROlHL-21654-0! Autonomic determinants of arrhythmia
due to ischemia (cats)
ROlHL-21742-01 Frequency-dependent drug actions in
cardiac muscle (rabbits)
ROlHL-2 2 154-01 Cardiac adaptation to physical training
(dog)
ROlHL-22225-01 Hormonal regulation of blood pressure
and blood flow (human, animals)
' ROlHL-22226-01 Autonomic nervous elements in the
developing heart (rabbits)
ROlHL-22418-01 Neural control ol cardiorespiratory
lunction (cats)
R0I!IL-22426-01 Initiation of the heartbeat-A voltage-
clamp study (bulllrogs. rabbits)
371
** ROIHL 22484 01 Neural control ol cardiac conduction and
excitation (dogs)
ROIHI 22715 01 Neural integration ol the cardiovascular
reflexes (dogsl)
NERVOUS SYSTEM AUTONOMIC, AUTONOMIC
GANGLIA
SEE ALSO NERVOUS SYSTEM AUTONOMIC. SYMPATHETIC
GANGLIA
POIHL 143880/ 0212 Regulation of the circulation in
pathological slates Role of dopamine in autonomic
activity
ROIHL 1737003 Synaptic chemistry and cardioregulation
in Limulus
ROIHL 2040003 Diabetic neuropathy and peripheral
vascular diseases (human, hamsters)
NERVOUS SYSTEM AUTONOMIC, AUTONOMIC
REFLEXES
M ROIHL 05883 18 Reflex control of resistance and
capacitance vessels
** ROIHL 05883-18 0002 Reflex control ol resistance and
capacitance vessels Adenosine, adenine nucleotides and
vascular smooth muscle (dog)
ROIHL 05883 18 0005 Reflex control ol resistance and
capacitance vessels Dilferential blockade of medullated
and non medullated vagal aflerents in the cat
** ROlHL-05883-18 0006 Reflex control ol resistance and
capacitance vessels Cardiopulmonary vagal allerents in
the conscious dog
M P01HL-08e82 15 Regulation ol the cardiovascular system
POlHL-08682 15 0005 Regulation ol the cardiovascular
system Smooth muscle and mechanical properties ol
blood vessels (dogs, human)
POlHL-08682-15 0015 Regulation ol the cardiovascular
system - Projection ol autonomic nerves onto the heart
(dog)
POlHL-08682-15 0018 Regulation ol the cardiovascular
system - Functional implications of cardiac allerent nerves
(dogs)
POlHL-08682-15 0021 Regulation ol the cardiovascular
system - Hypoglycemia in pathogenesis of shock (dog)
POlHL-08682-15 0024 Regulation of the cardiovascular
system - Morphology of the spinal sympathetic system (cat)
" POlHL-08682-15 0027 Regulation ol the cardiovascular
system - Cardiac mechanoreceptors-Reflex regulation of
renal function (dogs)
** POlHL-10436-13 0014 A multidisciplinary study of
congenital heart disease - Cardiovascular pharmacology
(dog)
** ROlHL-10951 11 Neural control of the heart (dogs, rats)
** POlHL-12738-10 0134 Physiologic pharmacology and its
clinical applications - Adenylate cyclase and cAMP
phosphodiesterase in cardiac development (dogs)
P50HL-14153-07 0013 Johns Hopkins Lung Center-
Chronic diseases ol airways - Pulmonary mechanics and
mediators ol allergic reactions (guinea pigs, human)
P50HL-14 159-08 0018 Specialized center ol research in
hypertension ■ Sympathetic nervous system in hypertension
(rats)
POlHL-169 10-05 0002 Regulation ol the peripheral
circulation - Coronary circulation (dogs)
P50HL17655-04 0014 Study ol ischemic heart disease -
Blood How and gas tension in myocardial ischemia and
infarction (dog. monkey)
P50HL-17667-04 0031 Study of ischemic heart disease -
Pathophysiology in ischemic heart disease (dog, cat, rabbit.
monkey)
POlHL-1897403 0001 Experimental neurogenic
hypertension program - Central neural systems regulating
arterial pressure (rabbits)
P50HL-19185-02 0003 Pulmonary SCOR -Neonatal
respiratory distress syndromes - Factors affecting formation
and release ol pulmonary surfactant in fetal lambs
** ROlHL-22296-01 Autonomic mechanisms in man
** ROlHL-22581-02 Neurocirculatory control in diabetes
mellitus (human)
NERVOUS SYSTEM AUTONOMIC, HEART
INNERVATION
SEE ALSO HEART. CONDUCTION SYSTEM
ROlHL-02953-17 Autonomic and cardiovascular
pharmacology (rats, rabbits, dogs, guinea pigs)
** ROlHL-05883-18 0008 Reflex control ol resistance and
capacitance vessels Oxygen consumption ol the
chronically denervated dog heart
POlHL-06285-18 0133 Cardiovascular-respiratory
physiology and biochemistry - Decreased uterine blood flow
and fetal development (lambs)
POlHL-06285-18 0153 Cardiovascular-respiratory
physiology and biochemistry Myocardial mechanics and
pharmacology in isolated papillary muscle (animals)
** POlHL-06285-18 0180 Cardiovascular-respiratory
physiology and biochemistry - Vagal C-fibers and their
influence on visceral and somatic function (animals)
M POlHL-063 12-17 Surgical cardiology
POlHL-063 12-17 0023 Surgical cardiology - Ellect ol
denervation on atherosclerosis
** POlHL-06312-17 0025 Surgical cardiology - Effect ol
denervation on arrhythmias and function with coronary
occlusion (dogs)
R01HL-0704716 Comparative study of cardiac conduction
system (human, birds, mammals)
NER
POlHt 08687 15 Regulation «l the cardiovstcular tyitem
POIHI 08682 15 0011 Regulation ol the cardiovascular
system Histochemistry and ultraslruclure ol heart
innervation (dogs, ground squirrels)
POIHI 08682 15 0015 Regulation ol the cardiovascular
system Pro)ectior ol autonomic nerves onto the heart
(dog)
POIHL 08682 15 0016 Regulation of the cardiovascular
system Shitting cardiac pacemakers and AV nodal
activation (dog)
POIHL 08682 15 0017 Regulation ol the cardiovascular
system Neurally induced cardiac dysrhythmias (dog)
POIHL 08682 15 0018 Regulation ol the cardiovascular
system Functional implications of cardiac afferent nerves
(dogs)
POIHL 08682 15 0022 Regulation ol the cardiovascular
system Blood pressure responses and preganglionic
sympathetic outtlow (cat)
POIHL 08682 15 0027 Regulation of the cardiovascular
system Cardiac mechanoreceptors -Reflex regulation ol
renal function (dogs)
POIHL'08682 15 0033 Regulation ol the cardiovascular
system Functional and anatomical relations during
cardiac re innervation (dog)
POIHL 12738 10 0108 Physiologic pharmacology and its
clinical applications Developmental electrophysiology and
pharmacology (human, animais)
POIHL 13108 09 Clinical heart transplantation
POIHL 13108 09 0008 Clinical heart transplantation •
Physiology and pharmacology ol the transplanted human
heart
POlHL-13108-09 0017 Clinical heart transplantation
Electrophysiology ol the transplanted denervated human
heart
POIHL 13108-09 0018 Clinical heart transplantation -
Electrophysiologic studies of cardiac drugs in the
denervated heart
POIHL 13108-09 0019 Clinical heart transplantation ■
Effect of autonomic ner./ous system on arrhythmias
(human)
' POlHL-13108-09 0020 Clinical heart transplantation
Autonomic neural studies in the denervated heart (human)
' POlHL-13108-09 0022 Clinical heart transplantation -
Studies on cardiac receptors (human)
' POlHL-13108-09 0023 Clinical heart transplantation -
Adaptive mechanisms ol the denervated heart (human)
' POlHL-13108-09 0024 Clinical heart transplantation -
Response ol denervated heart to stress -Noninvasive
(human)
P01HL13480-09 Cardiac electrophysiology
POlHL-1348009 0026 Cardiac electrophysiology Neural
inlluences on cardiac electrophysiology and contraction
(dog. cat)
ROlHL-13666-06 Pharmacology of genesis ol cardiac
rhythmicity (rats, cats)
POlHL-13737-07 0027 Assisted circulation - Optimization
of cardiac assistance (dogs)
ROlHL-13920 07 Expanding the role ol surgery ol atrial
dysrhythmias (dogs)
' POlHL-14388-07 0179 Regulation of the circulation in
pathological states - Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
POlHL-14388-07 0215 Regulation of the circulation in
pathological states Left ventricle model in
pathophysiologic states
* ROlHL-14713-06 Hypothermia and the heart (bats, guinea
pigs)
ROlHL-1483206 Myocardial cells -Autonomic and rhythmic
mechanisms (chick embryo, rats)
ROlHL-16511-04 Sympathetic afferent activity of cardiac
origin (dogs, monkeys)
* ROlHL-16657-06 Innervation of coronary arteries and heart
(rats)
POlHL-16910-05 0002 Regulation of the peripheral
circulation - Coronary circulation (dogs)
POlHL-16910-05 0007 Regulation ol the peripheral
circulation - CNS -Behavioral inlluences on circulation
(baboons)
* ROlHL-17367-05 Functional sympathetic development in
neonatal hearts (dogs, human)
ROlHL-17629-03 Developmental aspects ol cardiovascular
lunction (human, cats, rabbits)
P50HL-17648 04 0026 Study ol ischemic heart disease -
Control of muscle cell proliferation (organ culture)
* P50HL-17648-04 0028 Study of ischemic heart disease -
Electrophysiology of sympathetic innervation in tissue
culture
P50HL-17655-04 0001 Study ol ischemic heart disease •
Intravenous nitroglycerin-Vcntricular lunction and inlarct
size (human, dog)
P50HL-17667-04 0031 Study of ischemic heart disease -
Pathophysiology in ischemic heart disease (dog. cat. rabbit.
monkey)
* ROlHL-17799-02 The presence and significance of heart
acetylcholine (cats)
* ROlHL-18517-03 Intrinsic innervation of the heart (dogs)
ROlHL-18711-03 Electrophysiology of heart cells (rats.
chicks)
* ROlHL-18795-04 Ischemic arrhythmias -Effect of
autonomic tone (dogs. rats, guinea pigs)
ROlHL-18796-04 Expenmental cardiac arrhythmias (dogs)
(contd)
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
**Oriented significantly to above subiect.
M Grant has subprojects descnbmg specific research aspects.
See Appendix for investigator's name and grant number
NER
M ROlHL-1879804 Nervous and ionic factors in sudden
cardiac death
" R01HL18798-04 0003 Nervous and ionic factors in
sudden cardiac death - Left stellectomy in the prevention
of sudden death (dogs)
P01HL18974-03 0001 Experimental neurogenic
hypertension program - Central neural systems regulating
arterial pressure (rabbits)
ROlHL-19009-03 Morphomefric analysis of the sinoatrial
node (ferret)
ROlHL-19257-03 Cardiovascular adjustment to behavioral
stress (dog)
ROlHL-19343-03 Behavioral influences on cardiac
contractility (monkeys)
R01HL19974-02 Psychologic-behavioral influences on
heart pathology (rats)
ROlHL-2044602 Autonomic neuropathy in diabetic mice
(also rats)
R01HL-2H9502 Innervation of the heart ■Acetylcholine
receptors (frogs)
ROlHL-22226-01 Autonomic nervous elements in the
developing heart (rabbits)
R23HL-2224502 Functional characteristics of atrial
receptors (rats)
ROlHL-22581-02 Neurocirculatory control in diabetes
mellitus (human)
R23HL 22775-01 Muscarinic receptors in the developing
heart (chick embryo)
NERVOUS SYSTEM AUTONOMIC,
PARASYMPATHETIC NERVOUS SYSTEM
SEE ALSO NERVOUS SYSTEM. CRANIAL NERVES. URYNGEAL
NERVES
SEE ALSO NERVOUS SYSTEM. CRANIAL NERVES VAGUS
SEE ALSO NEUROTRANSMITTER RECEPTORS. CHOLINERGIC
RECEPTORS
ROlHL-01755-25 Fetal and neonatal cardiovascular
function (sheep)
POIHL-0628518 0189 Cardiovascular-respiratory
physiology and biochemistry - Mucociliary clearance (cats,
dogs)
M P01HL-08682I5 Regulation of the cardiovascular system
POlHL-0868215 0011 Regulation of the cardiovascular
system - Histochemistry and ultrastructure of heart
innervation (dogs, ground squirrels)
** POlHL-0868215 0015 Regulation of the cardiovascular
system - Projection of autonomic nerves onto the heart
(dog)
POlHL-08682-15 0016 Regulation of the cardiovascular
system ■ Shifting cardiac pacemakers and AV nodal
activation (dog)
POlHL-08682-15 0018 Regulation of the cardiovascular
system - Functional implications of cardiac afferent nerves
(dogs)
P50HL-14153-07 0017 Johns Hopkins Lung Center-
Chronic diseases of airways - Collateral ventilation and
pulmonary interdependence (pig. dog. human)
POlHL-14388-07 0211 Regulation of the circulation in
pathological states - Choline acetyltransferase activity
(rats)
P50HL1506I-07 0005 Response of lung to injury Airway
smooth muscle in health and disease (dogs, guinea pigs)
ROlHL-17768-04 Development of collateral ventilation
(dogs. fish, horses)
R01HL17799-02 The presence and significance of heart
acetylcholine (cats)
ROIHL-18795-04 Ischemic arrhythmias -Effect of
autonomic tone (dogs. rats, guinea pigs)
ROlHL-18798-04 0003 Nervous and ionic factors in
sudden cardiac death - Left stellectomy in the prevention
of sudden death (dogs)
P50HL-1915602 0004 Pulmonary SCOR-Chronic diseases
of airways ■ Interactions between mast cells, mediators
and nerves in canine asthma
ROlHL-22426-01 Initiation of the heartbeat-A voltage-
clamp study (bullfrogs, rabbits)
ROlHL-23604-01 Hepatic microvascular regulatory
mechanisms (rat)
NERVOUS SYSTEM AUTONOMIC, SPLANCHNIC
NERVES
POlHL-14388-07 0185 Regulation of the circulation in
pathological states - Reflex control of venous tone (human.
rabbits, dogs)
POlHL-14388 07 0209 Regulation of the circulation in
pathological states - Neural regulation of vascular
resistance in human hypertension
R01HL16454-03 Vascular muscle reactivity in
hypertension (human, rats)
ROlHL-20864-01 Postnatal maturation of cardiovascular
regulatory system (minipig)
ROIHL-22732-01 Central organization of cardiac afferent
nerves (cats, monkeys)
NERVOUS SYSTEM AUTONOMIC, SYMPATHETIC
GANGLIA
SEE ALSO NERVOUS SYSTEM. PARAGANGLIA
R01HL-03359-I4 Morphopharmacology of vascular
adrenergic transmission (rabbits, rats)
ROlHL-13187-09 Central neural control of cardiovascular
function (cats)
372
" P50HL-17648-04 0028 Study of ischemic heart disease -
Electrophysiology of sympathetic innervation in tissue
culture
ROlHL-18798-04 0003 Nervous and ionic factors in
sudden cardiac death - Left stellectomy in the prevention
of sudden death (dogs)
R01HL19251-03 An index of sympathetic activity in
hypertension (rats)
ROlHL-21351-02 Renal and vascular control by
sympathetic ganglia (animals)
ROIHL 2167301 Pathophysiology of venous changes in
hypertension (rats, rabbits, human, dogs)
NERVOUS SYSTEM AUTONOMIC, SYMPATHETIC
NERVOUS SYSTEM
SEE ALSO NERVOUS SYSTEM AUTONOMIC, SPUNCHNIC
NERVES
SEE ALSO NEUROTRANSMITTERS RECEPTORS. ADRENERGIC
RECEPTORS
ROlHL-00487-29 Vasomotor tone and venous return
(human, dogs, monkeys )
R01HL01755-25 Fetal and neonatal cardiovascular
function (sheep)
" R01HL05883-18 0003 Reflex control of resistance and
capacitance vessels Cardiac glycosides and sympathetic
nerve terminals in vascular smooth muscle
ROlHL-06143-18 Response of the totally denervated heart
to exercise (dogs)
POIHL-0628518 0180 Cardiovascular-respiratory
physiology and biochemistry - Vagal Cfibers and their
influence on visceral and somatic function (animals)
P01HL0629618 0007 Cardiovascular and pulmonary
adaptation to stress - Cardiovascular control during
isometric exercise (cats)
" POlHL-06835-17 0043 Cardiovascular disease - Lett
atrial receptor activity by the sympathetic nervous system
(dogs)
POlHL-06835-17 0045 Cardiovascular disease - Pressure-
volumerenin relationship in human hypertension
POlHL-06835-17 0051 Cardiovascular disease -
Cardiopulmonary volume in hypertension (human)
ROlHL-07723 15 Reflex control of vascular capacitance in
shock
R01HL08359-14 Morphopharmacology of vascular
adrenergic transmission (rabbits, rats)
R01HL08659-14 Myocardial performance and metabolism
in the newborn (sheep)
M POlHL-0868215 Regulation of the cardiovascular system
POlHL-08682-15 0011 Regulation of the cardiovascular
system Histochemistry and ultrastructure of heart
innervation (dogs, ground squirrels)
POlHL-0868215 0017 Regulation of the cardiovascular
system - Neurally induced cardiac dysrhythmias (dog)
POIHL-0868215 0018 Regulation of the cardiovascular
system - Functional implications of cardiac afferent nerves
(dogs)
•* POlHL-0868215 0022 Regulation of the cardiovascular
system - Blood pressure responses and preganglionic
sympathetic outflow (cat)
POlHL-08682-15 0023 Regulation of the cardiovascular
system - Cardiovascular control -Effects of spinal pathways
lesions (dog)
** P01HL08682-15 0024 Regulation of the cardiovascular
system - Morphology of the spinal sympathetic system (cat)
" POlHL-08682-15 0025 Regulation of the cardiovascular
system - Physiology of preganglionic cell bodies (cat)
POlHL-08682-15 0027 Regulation of the cardiovascular
system - Cardiac mechanoreceptors-Reflcx regulation of
renal function (dogs)
POlHL-08682-15 0033 Regulation of the cardiovascular
system - Functional and anatomical relations during
cardiac re-innervation (dog)
♦* POlHL-08682-15 0038 Regulation of the cardiovascular
system ■ Control of pulmonary circulation (dogs)
POlHL-1053912 0023 Pathophysiology of circulation -
The relaxation response and therapy of disease states
(human)
R01HL10951-11 Neural control of the heart (dogs rats)
POlHL-11414-11 0028 Thrombosis and atherosclerosis
program ■ Catecholamine metabolism in the lung (rat)
P01HL11678-11 0031 Cardiovascular dynamics and their
control - Hypertension caused by stimulation of renal
sympathetic nerves (dogs)
POlHL-1167811 0069 Cardiovascular dynamics and their
control - Nervous control of the cirulation (dogs)
ROlHL-1 1802-10 Cardiovascular surgical research (dogs,
sheep, swine, cats, monkeys)
POlHL-12373-10 0012 Cardiopulmonary physiology and
pathophysiology - Biochemistry of the sympathetic nervous
system (rats, rabbits, pigeons)
ROlHL-124 15-10 Evaluation of left ventricular function
(dogs, rabbits)
ROlHL-12421-10 Pathophysiology of circulatory shock
(dogs, baboons)
P01HL12738-10 0135 Physiologic pharmacology and its
clinical applications - Myocardial cells in tissue culture
(rats, chick embryo)
R01HL12827-08 Regulation of sodium excretion (dogs,
rats)
ROlHL-13134-07 Mechanism of chemoreceptor discharge
(cats)
ROlHL-13427-09 Neural control of blood volume (monkeys,
dogs)
NER
ROIHL 13623-08 Atrial receptors (dogs)
P50HL14159-08 0008 Specialized center of research in
hypertension - Renal function and sodium metabolism in
hypertension (rats, human, rabbits)
** P50HL-14159-08 0018 Specialized center of research in
hypertension - Sympathetic nervous system in hypertension
(rats)
** P50HL-14159-08 0020 Specialized center of research in
hypertension - Renin-mineralocorticoid system in
hypertension (human, rat, dog)
P50HL-1415908 0021 Specialized center of research in
hypertension Genetic studies of the physiology of
hypertension (human, rats)
POIHL- 14388-0 7 0160 Regulation of the circulation in
pathological states Mechanism of the antihypertensive
effect of training (rats)
POlHL-1438807 0178 Regulation of the circulation in
pathological states - Structural and functional
consequences of denervation (rats)
POlHL-14388-07 0179 Regulation of the circulation in
pathological states - Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
POlHL-14388-07 0180 Regulation of the circulation in
pathological states ■ Regulation of cerebral blood flow
(dogs, monkeys)
P01HL14388-07 0187 Regulation of the circulation in
pathological states - Histamine and circulatory control
POIHL 14388-07 0198 Regulation of the circulation in
pathological states - Humoral factors in vascular reactivity
in spontaneously hypertensive rats
" POlHL-14388-07 0201 Regulation of the circulation m
pathological states Central sympathetic discharge in
spontaneously hypertensive rats
•* POlHL-14388-07 0202 Regulation of the circulation in
pathological states - Development of hypertension in
spontaneously hypertensive rats
** POlHL-14388-07 0203 Regulation of the circulation in
pathological states - Activation of sympathetic nervous
systems in spontaneously hyperactive rats
P01HL14388-07 0209 Regulation of the circulation in
pathological states Neural regulation of vascular
resistance in human hypertension
POlHL-14388-07 0212 Regulation of the circulation in
pathological states - Role of dopamine in autonomic
activity
POlHL-14388-07 0213 Regulation of the circulation in
pathological states • Regulation of the heart and peripheral
circulation in heart failure
POlHL-14388-07 0229 Regulation of the circulation in
pathological states - Mechanism of postural hypotension
(human)
POlHL-14388-07 0234 Regulation of the circulation in
pathological states - Effects of antiarrhythmic drugs on the
autonomic system (dogs)
ROlHL-14560-07 Hypertension produced by sympathetic
dysfunction (human, rats)
ROIHL 1485407 Lung and tissue mechanics (monkeys
dogs)
POlHL-1498507 0007 Adaptation to hypoxia - Control of
pulmonary circulation, histamine and the sympathetics
(animals)
P50HL-15061-07 0005 Response of lung to injury - Airway
smooth muscle in health and disease (dogs, guinea pigs)
ROlHL-15392-06 Autonomic and circulatory actions of
anesthetics (dog, cat. rabbit, monkey)
ROlHL-15444-06 Neonatal development of adrenergic
receptor mechanisms (pigs)
ROlHL-15580-06 Humoral control of pulmonary and
systemic circulation (animals)
ROlHL-15758-06 Catecholamine release in the heart
(dogs)
ROlHL-15805-06 Cerebral arterial tone and reactivih
(rabbits)
ROlHL-16066-05 Studies on neurogenic control of the
circulation (human, dogs)
ROlHL-16511-04 Sympathetic afferent activity of cardiac
origin (dogs, monkeys)
ROlHL-16657-06 Innervation of coronary arteries and heart
(rats)
ROlHL-16768-04 The sympathetic nervous system and the
arterial wall (rabbits, pigeons)
POlHL-16910-05 0005 Regulation of the peripheral
circulation - Control of circulation by baroreceptor and
chemoreceptor reflexes (dog. monkey)
POlHL-16910-05 0008 Regulation of the peripheral
circulation - Circulation to bone (dogs, baboons)
ROlHL-17487-04 Adrenergic-vasoregulation interactions in
hypertension (human)
ROlHL-17631-05 Experimental congestive heart failure and
hypertrophy (cats)
P50HL-17646-04 0017 Study of ischemic heart disease -
Dysrhythmia associated with acute myocardial infarction
(human, cat)
P50HL-I7648-04 0026 Study of ischemic heart disease -
Control of muscle cell proliferation (organ culture)
ROlHL-17768-04 Development of collateral ventilation
(dogs. fish, horses)
ROlHL-17796-04 Importance of aminosugars in digitalis
activity (cats, rabbits)
ROlHL-17799-02 The presence and significance of heart
acetylcholine (cats)
•ExclurJes routine methodology OR covers only general projects which preclude indexing
Onented significantly to above subject.
at the specific level.
M Grant has subprojects describing specific research aspects,
see Appendix for investigators name and grant number.
(contd)
^^£iS£$]S
NER
ROIHL 178b303 Peiiphetal citculstion in heail Imluie
(animals)
ROIHI 17903 03 Regional ciiculatoiy casponses lo hypoxia
(fats, cats, rabbits)
R0IHL'179S8C4 Ciiculatory effects of opciant
cardiovascular control (baboons)
ROIHL 1809Si 04 Human dopamine beta hydroxylase (also
cattle)
PSOHL 1831803 0001 Pathoienesis and complications of
hypertension Core clinical program
P50HL 18318 03 0011 Pathogenesis and complications of
hypertension Adrenergic function Renin and
mineralocorlicoid activity (human)
P50HL 1832304 0041 SCOR hypertension center
Measurement of sympathetic response in hypertensive
patients
R01HL18340 04 Electron microscopy of the
juxtaglomerular apparatus (rats)
R01HL18601 01 Regulation of neurotransmitter release by
adenosine (rats)
R01HL18795 04 Ischemic arrhythmias Effect of
autonomic tone (dogs. rats, guinea pigs)
ROIHL 18796 04 Experimental cardiac arrhythmias (dogs)
ROIHL 1882403 Mechanisms of heart failure in
myopathic hamster
POIHL 18974 03 0008 Experimental neurogenic
hypertension program Monoamines and hypertension
(rats)
R01HL18976-03 Blood pressure control Relation to
behavioral stress (human, dog)
R01HL1913404 Angiotensin, prostaglandins, adrenergic
interactions (rats, rabbits)
P50HL 1915602 0004 Pulmonary SCOR -Chronic diseases
of airways Interactions between mast cells, mediators
and nerves in canine asthma
P50HL-1919002 0006 Pulmonary SCOR-Pathophysiology.
management of IRDS Asphyxia -Respiratory control (dogs)
' ROlHL-19257-03 Cardiovascular ad)ustment to behavioral
stress (dog)
R01HL1997402 Psychologic-behavioral influences on
heart pathology (rats)
ROlHL-19997-02 Prostaglandin precursors and intestinal
vasculature (cats, rabbits)
' ROlHL-20206-02 Carbohydrates-nucleotides and adrenergic
interactions (rabbits, cats, rats)
ROlHL-2039903 Vascular control in experimental diabetes
mellitus (dog)
ROlHL-2042903 Study of effects of diabetes reactivity
(miniature pigs, rats)
ROlHL-20439-02 Effects of insulin on neurovascular
transmission (human, rats, rabbits, hamsters)
' ROlHL-2044602 Autonomic neuropathy in diabetic mice
(also rats)
' ROlHL-20542-03 Regional hemodynamics in spontaneous
hypertension (rats)
R01HL-20564-02 Pathogenesis of peripheral arterial
disease (rats, rabbits)
' POlHL-20581-01 0002 Vascular neuroeffector
mechanisms in health and disease - Trophic interaction
between adrenergic nerves and vascular smooth muscle
* POlHL-20581-01 0005 Vascular neuroeffector
mechanisms in health and disease - Changes in the
neuroeffector mechanism in hypertension (rabbits)
POlHL-20581-01 0006 Vascular neuroeffector
mechanisms in health and disease - Neuroeffector
mechanism in arteries and veins in hypertension (human)
* ROlHL-20663-02 Regulation of skin blood flow in man
ROlHL-20768-02 Mechanisms of circulatory regulation in
heart failure (guinea pigs)
ROlHL-20800-17 Neural basis of respiratory and
vasomotor activity (cats)
R23HL-21042-01 Cardiopulmonary reflexes and their
anatomical basis (dogs)
R23HL-21150-02 Regulation of airway mucous glands and
ion transport (dogs, ascaris)
R23HL-21462-02 Mechanical interactions between ventricle
arteries (dogs)
ROlHL-21532-02 Cardiovascular homeostasis and learning
(frogs, rats, human)
ROlHL-21860-18 Factors influencing responses to
adrenergic drugs (guinea pigs. rats, cats)
ROlHL-21893-01 Blood volume distribution in hypertension
(human)
R23HL-21973-01 Catecholamine metabolism and the heart
(human, guinea pigs)
ROlHL-22170-01 Factors influencing transmission at
adrenergic synpases
R01HL-22I72-01 Hypotension, renal ischemia and effect of
mannitol (dogs, rats)
* ROlHL-22306-01 Renal catecholamines- Pathophysiology
of hypertension (dogs)
ROlHL-22361-01 Regulation of cardiac adaptation to
exercise (rats)
ROlHL-22426-01 Initiation of the hearlbeat-A voltage-
clamp study (bullfrogs, rabbits)
R01HL-22484-01
excitation (dogs)
ROlHL-22594-01
failure (dogs)
ROIHL 22667-01
Neural control of cardiac conduction and
Reflex control of the circulation in heart
3/3
R23HI 22669 01 Caidiovastulai iiftrcls from vistei.il
afleients (dogs)
R23HI 22747 01 Cardiodynamics and hypertension under
cerebellar control (dogs)
R23HL 227 75 01 Muscarinic receptors in the developing
heart (chick embrYO)
ROIHL 22809 01 Coronary prone behavior and
cardiovascular reactivity (human)
ROIHL 22868 01 Presynaptic regulatory mechanisms in
hypertension (rats, dogs)
ROIHL 22873 01 Adrenoceptor interconversion and
hormone homeostasis
ROIHL 23604 01 Hepatic microvascular regulatory
mechanisms (rat)
ROIHL 23726 01 Treatment of ventricular arrhythmias with
propranolol (human)
NERVOUS SYSTEM CENTRAL
SEE ALSO BRAIN
SEE ALSO NERVOUS DISORDERS CENTRAL (GENERAL)
** ROIHL 03429 18 Central nervous system and coronary
heart disease (human)
•• POlHL-08805 15 0046 Regulation of ventilation and
pulmonary circulation Sites and modes of interaction of
peripheral and central chemoreceptors
•* POIHL 08899-14 0026 Tolerance to respiratory gases in
health and disease Effects of oxygen on central nervous
system functions (rats, rabbits)
** P01HL08899 14 0043 Tolerance to respiratory gases in
health and disease • Oxygen effects upon CNS and sensory
functions (human)
POlHL-08899-14 0044 Tolerance to respiratory gases in
health and disease Influence of high oxygen pressures on
cognition and performance
P01HL08899-14 0047 Tolerance to respiratory gases in
health and disease Oxygen effects on visual function
(human)
P01HL08899-14 0064
health and disease
P01HL14388-07 0187
pathological states -
POlHL-14388-07 0193
pathological states
Mechanisms of baroreceptor adaptation
in hypertension (dogs)
Tolerance to respiratory gases in
Narcotic effects of inert gases on
functional systems (rats)
POlHL-08899-14 0078 Tolerance to respiratory gases in
health and disease - Isobaric gas counterdiffusion -Sensory.
cutaneous and systemic function (animals)
POlHL-12738-10 0042 Physiologic pharmacology and its
clinical applications Centrogenic cardiac arrhythmias
(cats)
ROlHL-1299009 Control of antidiuretic hormone secretion
and metabolism (dogs. rats, rabbits)
ROlHL-13187-09 Central neural control of cardiovascular
function (cats)
POlHL-14388 07 0164 Regulation of the circulation in
pathological states - Hyperkinetic heart syndrome (human)
POlHL-14388-07 0180 Regulation of the circulation in
pathological states - Regulation of cerebral blood flow
(dogs, monkeys)
Regulation of the circulation in
Histamine and circulatory control
Regulation of the circulation in
Ontogenesis of central nervous system
amines in hypertension (rats)
POlHL-14388-07 0201 Regulation of the circulation in
pathological states Central sympathetic discharge in
spontaneously hypertensive rats
POlHL-14388-07 0202 Regulation of the circulation in
pathological states - Development of hypertension in
spontaneously hypertensive rats
POlHL-14388-07 0203 Regulation of the circulation in
pathological states - Activation of sympathetic nervous
systems in spontaneously hyperactive rats
ROlHL-163 15-05 Analysis of interaction between CNS
vasomotor systems (cats, rats)
ROlHL-16658-05 Intrarenal regulation of sodium
reabsorption
POlHL-16910-05 0007 Regulation of the peripheral
circulation - CNS-Behavioral influences on circulation
(baboons)
ROlHL-17401-03 Mechanisms in angiotensin induced
hypertension (cats, dogs)
POlHL-17871-04 0013 Kidney, sodium, cardiac output.
arterioles and hypertension - Perfusion pressure and renal
sodium excretion (rats)
ROlHL-18601-01 Regulation of neurotransmitter release by
adenosine (rats)
ROlHL-18657-03 Pharmacologic studies on neurogenic
digitalis effects (human, cats, dogs)
ROlHL-18994-03 Substance P -Occurrence, pharmacology
and physiology (mammals non-human, human)
R01HL19320-03 Angiotensin neuropharmacology-
Relationship to sodium
ROlHL-20864-01 Postnatal maturation of cardiovascular
regulatory system (minipig)
ROlHL-21799-01 Circumventricular sites of pressor action
of angiotensin II (rats)
ROlHL-226 17-01 Angiotensin, hypertension and the CNS
(sheep)
ROlHL-227 15-01
reflexes (dogs))
ROlHL-22862-01
drugs (dogs)
ROlHL-23601-01
respiratory control
Neural integration of the cardiovascular
CNS-mediated effects of antiarrhythmic
Early hypoxia and development of
NERVOUS SYSTEM CENTRAL CEREBROSPINAL
FLUID
SEE ALSO CEREBROVASCUIAH '.rMIM HI OOU
CfRfBROSPINAI flUlO BARHK R
ROIHI 02888 2? lnterrelationi,hip', of r.irculation and
respiration (opossum, cats)
POlHt 0/896 15 0030 f nvifonmental biomedical research
program Narcosis caused by inert gases at raised
pressures (human, animals)
ROIHI 12564 09 Control of respiration and blood gases
(human, dog)
POIHI 13851 16 Cyclotron produced isotopes in biology
and medicine (human, animals)
POIHL 14388 07 0180 Regulation of the circulation in
pathological states Regulation of cerebral blood flow
(dogs, monkeys)
POIHL 1438807 0183
pathological states
Regulation of the circulation in
Vasopressin in cardiovascular
regulation (dogs, rats)
ROIHL 1546906 Human ventilatory adaptation (also.
dogs, ratsi
ROIHL 18351 03 Brain metabolism, acid base balance,
and respiration
** P50HL 19190 02 0006 Pulmonary SCOR Pathophysiology,
management of IRDS Asphyxia Respiratory control (dogs)
ROIHL 1932003 Angiotensin neuropharmacology
Relationship to sodium
ROIHL 22617-01 Angiotensin, hypertension and the CNS
(sheep)
NERVOUS SYSTEM CENTRAL, CEREBROSPINAL
FLUID FLOW
POlHL-10342 13 0019 The integrated function of
respiration and circulation Cerebral circulation and
metabolism (dogs)
NERVOUS SYSTEM CENTRAL, CEREBROSPINAL
FLUID PRESSURE
SEE ALSO NEUROPHYSIOLOGY. INTRACRANIAL PRESSURE
POlHL-11678-11 0057 Cardiovascular dynamics and their
control - Return of urine to circulation using cystico-caval
shunt (dogs)
NERVOUS SYSTEM CENTRAL, MENINGES, PIA
MATER
ROIHL 12775-08 Cerebral microcirculation (mice)
NERVOUS SYSTEM CENTRAL, MENINGES,
SUBARACHNOID SPACE
ROlHL-22573-01 Treatment of post surgical
vasoconstriction (dogs, monkeys, human, rats)
NERVOUS SYSTEM CENTRAL, PYRAMIDAL
TRACTS
POlHL-08682-15 0022 Regulation of the cardiovascular
system - Blood pressure responses and preganglionic
sympathetic outflow (cat)
NERVOUS SYSTEM CENTRAL, RETICULOSPINAL
TRACT
POlHL-08682-15 0022 Regulation of the cardiovascular
system • Blood pressure responses and preganglionic
sympathetic outflow (cat)
NERVOUS SYSTEM CENTRAL, SPINAL CORD
M POlHL-08682-15 Regulation of the cardiovascular system
** POlHL-08682-15 0022 Regulation of the cardiovascular
system - Blood pressure responses and preganglionic
sympathetic outflow (cat)
" POlHL-08682-15 0023 Regulation of the cardiovascular
system - Cardiovascular control-Effects of spinal pathways
lesions (dog)
** POlHL-08682-15 0024 Regulation of the cardiovascular
system Morphology of the spinal sympathetic system (cat)
" POlHL-08682 15 0025 Regulation of the cardiovascular
system - Physiology of preganglionic cell bodies (cat)
POIHL-14388-07 0193 Regulation of the circulation in
pathological states ■ Ontogenesis of central nervous system
amines in hypertension (rats)
ROlHL-16648-16 Integrated control of cardiovascular
activity (cats)
ROlHL-18994-03 Substance P-Occurrence, pharmacology
and physiology (mammals non-human, human)
NERVOUS SYSTEM CENTRAL, SPINAL CORD
MAPPING
POlHL-0868215 0024 Regulation of the cardiovascular
system - Morphology of the spinal sympathetic system (cat)
NERVOUS SYSTEM DISORDERS
SEE NERVOUS DISORDERS (GENERAL)
NERVOUS SYSTEM NEOPLASMS
SEE NEOPUSMS OF NERVOUS SYSTEM
NERVOUS SYSTEM REGENERATION
POlHL-08682-15 0011 Regulation of the cardiovascular
system - Histochemistry and ultrastruciure of heart
innervation (dogs, ground squirrels)
POlHL-08682-15 0016 Regulation of the cardiovascular
system - Shifting cardiac pacemakers and AV nodal
activation (dog)
(contd)
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
'•Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number
NEU
** POlHL-08682-15 0033 Regulation of the cardiovascular
system - Functional and anatomical relations during
cardiac reinnervation (dog)
POlHL-13108-09 0003 Clinical heart transplantation ■
Endomyocardial biopsy pathology
POlHL-18974.03 0012 Experimental neurogenic
hypertension program • Iramunohistochemistry of central
monoamine neurons (rats)
ROlHL-20446-02 Autonomic neuropathy in diabetic mice
(also rats)
NEURAL CONDUCTION
SEE NEUROPHYSIOLOGY. NEURAL CONDUCTION
NEURAL CONTROL (MECHANISMS)
SEE INFORMATION PROCESSING AND CONTROL (NEURAL)
NEURAL ENCODING (MECHANISMS)
SEE INFORMATION PROCESSING AND CONTROL (NEURAL)
NEURAL PROCESSING AND CONTROL
SEE INFORMATION PROCESSING AND CONTROL (NEURAL)
NEURAL RECRUITMENT
SEE NEUROPHYSIOLOGY, NEURAL RECRUITMENT
NEURAL TRANSMISSION
SEE NEUROPHYSIOLOGY, NEURAL TRANSMISSION
NEURAL TRANSMITTERS, BIOGENIC AMINES
SEE NEUROTRANSMIHERS (GENERAL)
NEURAMINIDASE
SEE CARBOHYDRASES, NEURAMINIDASE
NEUROANATOMY
SEE ALSO BRAIN MAPPING
SEE ALSO NERVOUS SYSTEM CENTRAL, SPINAL CORD
MAPPING
POlHL-08682-15 0015 Regulation of the cardiovascular
system - Projection of autonomic nerves onto the heart
(dog)
POlHL-08682-15 0024 Regulation of the cardiovascular
system ■ Morphology of the spinal sympathetic system (cat)
P01HL08682-15 0037 Regulation of the cardiovascular
system Central nervous regulation of cardiopulmonary
mechanisms (cats)
** POlHL-0880515 0039 Regulation of ventilation and
pulmonary circulation - Carotid body (cats)
P01HL11678-11 0069 Cardiovascular dynamics and their
control - Nervous control of the cirulation (dogs)
POlHL-14388-07 0183 Regulation of the circulation in
pathological states • Vasopressin in cardiovascular
regulation (dogs, rats)
R01HL-163I505 Analysis of interaction between CNS
vasomotor systems (cats, rats)
ROlHL-16430-05 Neural control of respiration (cats)
ROlHL-16511-04 Sympathetic afferent activity of cardiac
origin (dogs, monkeys)
POlHL-16910-05 0007 Regulation of the peripheral
circulation ■ CNS-Behavioral influences on circulation
(baboons)
R01HL1780004 Pulmonary reflexes-Central pathways
(cats, dogs, rabbits)
** P01HL1897403 0016 Experimental neurogenic
hypertension program - Neuroanatomy core
ROlHL-1899403 Substance P-Occurrence, pharmacology
and physiology (mammals non-human, human)
ROlHL-1904803 Structure of baroreceptors in
hypertension (rats)
ROlHL-19053-03 Vascular anatomy of the telencephalon
(human)
P50HL-1915602 0005 Pulmonary SCOR-Chronic diseases
of airways - Vagal receptors in the airway-Epithelial injury
and antigen (dog, cat. rabbit)
ROlHL-20548-02 Innervation of the lung (rats, monkeys)
ROlHL-2057403 Brain stem integration of chemoreceptor
activity (cats)
RC1HL-224I8-01
function (cats)
** ROlHL-22732-01 Central organization of cardiac afferent
nerves (cats, monkeys)
R23HL-2274701 Cardiodynamics and hypertension under
cerebellar control (dogs)
NEUROBLASTOMA
SEE NEOPUSMS OF NERVOUS SYSTEM, NEUROBLASTOMA
NEUROCHEMISTRY
SEE ALSO BRAIN METABOLISM
SEE ALSO NEUROTRANSMITTERS BIOSYNTHESIS
SEE ALSO NEUROTRANSMITTERS METABOLISM
POIHL-0789615 0014 Environmental biomedical research
program - Mechanisms of respiration and circulation
(human, dogs)
** POlHL-0789615 0032 Environmental biomedical research
program - Fluorometry study of brain exposed to hyperbaric
oxygen (dogs, cats)
" POlHL-08805-15 0044 Regulation of ventilation and
pulmonary circulation - Naurochemical Interactions in
rasplratory control (human, dogs, goats)
** P01HL-08805-1S 0045 Regulation of ventilation and
pulmonary circulation ■ Intagrtttd description of
nturochimlcil riiplntoiy control system
R01HL'12775-C8 Ciribnj inleroclrculitlon (mica)
Neural control of cardiorespiratory
ROlHL-17370-03
in Limulus
ROlHL-17907-04
(pigs, cats, rats)
POlHL-18974-03
program
P01HL18974-03 0009
hypertension program
hydroxylase (rats)
POlHL-1897403 0010
hypertension program
PNMT in brain (rats)
P01HL1897403 0011
hypertension program
374
Synaptic chemistry and cardioregulation
Brain regulation of cardiac arrhythmia
Experimental neurogenic hypertension
Experimental neurogenic
Biochemistry of brain tyrosine
Experimental neurogenic
Biochemistry and regulation of
Experimental neurogenic
Biochemistry and regulation of
brain tryptophane hydroxylase (rats)
** P01HL1897403 0012 Experimental neurogenic
hypertension program Immunohistochemistry of central
monoamine neurons (rats)
" POlHL-18974-03 0015 Experimental neurogenic
hypertension program - Neurochemistry core
** R01HL1899403 Substance P -Occurrence, pharmacology
and physiology (mammals non-human, human)
ROlHL-20384-09 Social stimulation, RNA and
cardiovascular disease (animals)
** ROlHL-20847-02 Respiratory neurochemical control
(human, goats)
NEUROEFFECTORS
SEE NERVOUS SYSTEM, NEUROEFFECTORS
NEUROENDOCRINE SYSTEMS
SEE ALSO ADRENAL MEDULLA
SEE ALSO NERVOUS SYSTEM, PARAGANGLIA
SEE ALSO NEUROHORMONES
SEE ALSO PITUITARYDIENCEPHALON (HORMONES)
SEE ALSO PITUITARY GUNO, NEUROHYPOPHYSIS
** P01HL0637017 0015 Cardiopulmonary and renal
pathology research center - Pathogenesis of chemically
induced tissue injury (rats)
POlHL-1 1678-11 0034 Cardiovascular dynamics and their
control - Renal function curves in intact dogs
P50HL-18323-04 0047 SCOR hypertension center -
Transcendental meditation and self-hypnosis -Hypertension
treatment (human)
" ROlHL-20384-09 Social stimulation, RNA and
cardiovascular disease (animals)
ROlHL-22259-01 Modification of susceptibility to oxygen
poisoning (rats)
** ROlHL-224 11-01 Neuroendocrine involvement in
hypertension (rats)
ROlHL-22873-01 Adrenoceptor interconversion and
hormone homeostasis
NEUROFIBRILS
SEE NERVOUS SYSTEM, NEURONS, NEUROFIBRILS
NEUROGENESIS
SEE NERVOUS SYSTEM. NEUROGENESIS
NEUROGENIC HYPERTENSION
SEE CARDIOVASCUUR DISORDERS, HYPERTENSION
(SYSTEMIC), NEUROGENIC HYPERTENSION
NEUROGLIA
SEE NERVOUS SYSTEM, NEUROGLIA
NEUROHORMONES
SEE ALSO ADRENAL MEDULLA HORMONES
SEE ALSO NERVE GROWTH FACTOR
SEE ALSO NEUROTRANSMIHERS (GENERAL)
SEE ALSO NEUROTRANSMinERS BIOSYNTHESIS
SEE ALSO PITUITARYDIENCEPHALON HORMONES,
NEUROHYPOPHYSEAL HORMONES
POlHL-06308-18 0025 Mechanisms and therapy of
circulatory disease - Subcellular calcium pools in the
genesis of arrhythmias (dogs)
** ROlHL-0928314 Pharmacology of molluscan hearts (also
rabbits)
" ROlHL-10897-12 Effects of hormones on cardiac
electrogenesis (rabbits, guinea pigs, dogs)
POlHL-14388-07 0179 Regulation of the circulation In
pathological states - Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
POlHL-14388-07 0183 Regulation of the circulation in
pathological states - Vasopressin in cardiovascular
regulation (dogs, rats)
ROlHL-18260-04 Cyclic nucleotide metabolism in lung
tissue (cattle)
R01HL1895203 Metabolism in perfused fetal and
newborn rabbit lungs
POlHL-19242-02 0004 Study of vascular smooth muscle ■
Cyclic nucleotide metabolism in smooth muscle cultures
(human, rats)
NEUROHUMORS (GENERAL)
SEE NEUROTRANSMITTERS (GENERAL)
NEUROHUMORS BIOSYNTHESIS
SEE NEUROTRANSMITTERS BIOSYNTHESIS
NEUROHYPOPHYSEAL HORMONES
SEE PITUITARY-DIENCEPHALON HORMONES,
NEUROHYPOPHYSEAL HORMONES
NEUROHYPOPHYSIS
SEE PITUITARY GLAND, NEUROHYPOPHYSIS
•Excludes routine mtthodoloiy OR covin only lenaral pnjicti which pncluda Indexing at thi sptclfic Itvil.
"Oitentad significantly to ibovt subjtct.
M Grant has subprojscts describing sptclfic riseirch aspects.
See Appendix tor Investigator's neme and grant number.
NEU
NEUROLOGIC CORRELATES OF BEHAVIOR
SEE NEUROPSYCHOLOGY (GENERAL)*
NEUROLOGIC EXAMINATIONS
SEE NERVOUS DISORDERS DIAGNOSIS (INCL EXAMS)*
NEUROLOGIC AAANIFESTATIONS
SEE ALSO NEUROMOTOR DISORDERS
SEE ALSO PSYCHOLOGY ABNORMAL, MENTAL DISORDERS
(GENERAL)
POlHL-0889914 0030 Tolerance to respiratory gases In
health and disease - Dynamic characteristics of respiratory
control components (human, cats)
POlHL-0889914 0064 Tolerance to respiratory gases in
health and disease - Narcotic effects of inert gases on
functional systems (rats)
POlHL-08899-14 0078 Tolerance to respiratory gases in
health and disease - Isobaric gas counterdiffusion-Sensory,
cutaneous and systemic function (animals)
NEUROLOGIC MANIFESTATIONS, HEADACHE
ROlHL-21117-01 Altitude adaptation in chronic lung
disease (human)
NEUROLOGIC MANIFESTATIONS, SLEEP
DISORDERS
P01HL10436-13 0005 A multidisciplinary study of
congenital heart disease - Pulmonary physiology In
congenital heart disease (human)
P01HL1498507 0009 Adaptation to hypoxia - Influence
of chemosensitivity on control of breathing during sleep
(human, dogs)
R01HL16325-03 Breathing patterns in man
ROlHL-21 117-01 Altitude adaptation in chronic lung
disease (human)
NEUROLOGIC AAANIFESTATIONS, SYNCOPE
R01HL18794-04 Prospective studies of conduction disease
(human)
NEUROLOGIC AAANIFESTATIONS,
UNCONSCIOUSNESS
R01HL16784-03 Lung tissue and water volume (human,
dogs)
NEUROLOGICAL DISEASES
SEE NERVOUS DISORDERS (GENERAL)
NEUROLOGICAL SCIENCES STUDY SECTION
** ROlHL-22868-01 Presynaptic regulatory mechanisms in
hypertension (rats, dogs)
NEUROLOGY STUDY SECTION
** ROlHL-1737003
in Limulus
** R01HL18590-03
(dogs, monkeys)
** ROlHL-20384-09 Social stimulation, RNA and
cardiovascular disease (animals)
** ROlHL-20800-17 Neural basis of respiratory and
vasomotor activity (cats)
** R23HL-22747-0I Cardiodynamics and hypertension under
cerebellar control (dogs)
** ROlHL-23614 02 Pharmacology of relaxation In smooth
muscle (mollusks)
NEUROLYMPHOMATOSIS OF FOWL
SEE NERVOUS DISORDERS CENTRAL. MAREK'S DISEASE
NEUROMOTOR DISORDERS
SEE ALSO BRAIN DISORDERS, CEREBELUR DISORDERS
SEE ALSO METABOLIC DISORDERS INBORN,
HEPATOLENTICULAR DEGENERATION
SEE ALSO METABOLIC DISORDERS INBORN,
HYPOUPOPROTEINEMIAS FAMILIAL,
ABETAUPOPROTEINEMIA
SEE ALSO MHABOLIC DISORDERS INBORN, MUSCULAR
DYSTROPHY
SEE ALSO METABOLIC DISORDERS INBORN, MYOTONIA
ATROPHICA
SEE ALSO MUSCUUR DISORDERS
SEE ALSO NERVOUS DISORDERS, MYELINOPATHIES, MULTIPLE
SCLEROSIS
SEE ALSO NERVOUS DISORDERS CENTRAL (GENERAL)
SEE ALSO NERVOUS DISORDERS PERIPHERAL
SEE ALSO NEUROMUSCUUR STIMULATORS (FOR
NEUROMOTOR DISORDERS)
ROlHL-0465119 Remote stimulation by radio-frequency
transmission (dogs, human)
** POlHL-14388-07 0218 Regulation of the circulation in
pathological states - Regional myocardial dyskinesis-Cause
assessment and reduction (dogs)
ROlHL-22022-01 Respiratory muscle dysfunction in
respiratory failure (human)
NEUROMOTOR DISORDERS, CONVULSIONS
SEE ALSO BRAIN DISORDERS, EPILEPSY
SEE ALSO NEUROMOTOR DISORDERS. MYOCLONUS
SEE ALSO NEUROPHARMACOLOGICAL AGENTS,
ANTICONVULSANTS
POlHL-07896'15 0049 Environmental biomedical resurch
program • Effects of hyperbaric oxygen end pressure on
cerebral enzymes (rats)
** R01HL'1277S-08 Cerebral microcirculation (mice)
(coirtd)
Synaptic chemistry and cardioregulation
Cerebral blood flow after cardiac arrest
ilS^SSSSS^-.
NEU
375
NiU
NEUROMOTOR DISORDERS, HYPERKINESIA
** POIHL 1438807 0164 Regulation ol the circulation in
patholo|ic(l jtatas Hypariilnatic tieail iyndiome Oiumtn)
POIHI 1438807 0179 Regulation ol ttie cliculation In
pathological states Cultured muscle cells and their cross-
Innervation in vitro (rats, sheep)
NEUROMOTOR DISORDERS, MYOCLONUS
SEE ALSO NEUROMOTOR DISORDERS. CONVULSIONS
R01H1217S6'U Vascular disease- Cytochemistry and
ultiastructute (human, rats. mice, hamsters)
NEUROMOTOR DISORDERS, NEUROMUSCULAR
(GENERAL)
SEE ALSO METABOLIC DISORDERS INBORN. MUSCUUR
DYSTROPHY
SEE ALSO METABOLIC DISORDERS INBORN. MYOTONIA
ATROPHICA
SEE ALSO METABOLIC DISORDERS INBORN. MYOTONIA
CONGENITA
ROlHL-13636-08 Effects of pharmacologic agents on heart
metabolism (human, rodents)
POlHL-17813 04 0006 Lung disease and the oxygenation
of blood and tissue Assessment of respiratory muscle
contractile force (human, dogs)
NEUROMOTOR DISORDERS, PARALYSIS
POlHL-2 1584-02 0003 Respiratory mechanics in normal
and abnormal states Effects of anesthesia on ventilation
and respiratory mechanics in man
*• POlHL-21584-02 0004 Respiratory mechanics in normal
and abnormal states Effects of anesthesia on respiratory
mechanics (dogs)
NEUROMOTOR DISORDERS, PARALYSIS,
PARAPLEGIA
P01HL-0880S-1S 0044 Regulation of ventilation and
pulmonary circulation Neurochemical interactions in
respiratory control (human, dogs, goats)
NEUROMOTOR DISORDERS, PARKINSON'S
DISEASE
SEE ALSO NEUROPHARMACOLOGICAL AGENTS.
ANTIPARKINSON DRUGS
ROlHL-19839-09 Factors in youth predisposing to chronic
diseases (former college students)
NEUROMOTOR DISORDERS, TREMOR
ROlHL-02888-22 Interrelationships of circulation and
respiration (opossum, cats)
NEUROMOTOR DISORDERS CHEMOTHERAPY
SEE ALSO MUSCLE RELA)(ANTS
SEE ALSO MUSCLE STIMUUNTS
SEE ALSO NEUROPHARMACOLOGICAL AGENTS,
ANTICONVULSANTS
SEE ALSO NEUROPHARMACOLOGICAL AGENTS,
ANTIPARKINSON DRUGS
** POlHL-07896-15 0030 Environmental biomedical research
program - Narcosis caused by inert gases at raised
pressures (human, animals)
NEUROMOTOR DISORDERS DIAGNOSIS (INCL
EXAMS)*
** POlHL-07896-15 0055 Environmental biomedical research
program - Cerebral blood flow by Xenon-133 inhalation
(human)
NEUROMOTOR EXAMINATIONS
SEE NEUROMOTOR DISORDERS DIAGNOSIS (INCL EXAMS)*
NEUROMOTOR SYSTEM, MOTOR NEURONS
** POlHL-0868215 0037 Regulation of the cardiovascular
system - Central nervous regulation of cardiopulmonary
mechanisms (cats)
POlHL-14414-07 0007 Environmental influences on
cardiorespiratory and cellular functions - Neural control of
respiration (human, cats)
** ROlHL-18007-05 Neural mechanisms controling motor act
of breathing (cats, human)
ROlHL-20548-02 Innervation of the lung (rats, monkeys)
ROlHL-21257-02 Breathing in sleep -Airway control and
blood gases (cats)
NEUROMOTOR SYSTEM, NEUROMUSCULAR
ASPECTS (GENERAL)
POlHL-20581-01 0002 Vascular neuroeffector
mechanisms in health and disease - Trophic interaction
between adrenergic nerves and vascular smooth muscle
POlHL.20581-01 0003 Vascular neuroeffector
mechanisms in health and disease - Cerebrovascular
neuroeffector characteristics (animals)
NEUROMOTOR SYSTEM, NEUROMUSCULAR
JUNCTION
P50HL-1 506 1-07 0005 Response of lung to injury ■ Airway
smooth muscle in health and disease (dogs, guinea pigs)
ROlHL-21195-02
receptors (frogs)
R23HL-22972-01
(rati, hamsters)
l«01HL-23210-01
pulmonity veiiels (cat, human)
Innervation of the heart-Acetylchollne
Microclrculatory function In hypotension
Biology of normal and hypertrophied
NEUROMOTOR SYSTEM, NEUROMUSCULAR
TRANSMISSION
SEE ALSO HEART. CONDUCTION SYSTEM
SEE ALSO MUSCLE FUNCTION. MUSCLE CONTRACTION
ROIHL 12647 08 Inactivation of norepinephrine in vascular
tissue
ROIHL 14523 07 Generation and regulation of force in
smooth muscle (animals)
ROIHL 1771504 Respiratory muscle afferents in
respiratory control (cats)
ROIHL 22201 01 Pharmacology and chemistry of
nudibranch tomns (guinea pigs. rats, mice)
ROIHL 23614 02 Pharmacology of relaxation in smooth
muscle (mollusks)
NEUROMOTOR SYSTEM, SENSORIMOTOR
SYSTEMS (GENERAL)
ROlHL-20548-02 Innervation of the lung (rats, monkeys)
ROIHL 22740 01 Behavior and cardiovascular disease-
Basic mechanisms (human)
NEUROMUSCULAR ASPECTS
SEE NEUROMOTOR SYSTEM. NEUROMUSCULAR ASPECTS
(GENERAL)
NEUROMUSCULAR BLOCKING AGENTS
SEE MUSCLE RELAXANTS. NEUROMUSCULAR BLOCKING
AGENTS
NEUROMUSCULAR BLOCKING AGENTS
DEPOLARIZING
SEE MUSCLE RELAXANTS. NEUROMUSCUUR BLOCKING
AGENTS DEPOLARIZING
NEUROMUSCULAR DISORDERS
SEE NEUROMOTOR DISORDERS, NEUROMUSCUUR (GENERAL)
NEUROMUSCULAR JUNCTION
SEE NEUROMOTOR SYSTEM, NEUROMUSCULAR JUNCTION
NEUROMUSCULAR STIMULANTS
SEE MUSCLE STIMULANTS
NEUROMUSCULAR STIMULATORS (FOR
NEUROMOTOR DISORDERS)
ROlHL-04651-19 Remote stimulation by radio-frequency
transmission (dogs, human)
NEUROMUSCULAR SYSTEM
SEE NEUROMOTOR SYSTEM. NEUROMUSCULAR ASPECTS
(GENERAL)
NEUROMUSCULAR TRANSMISSION
SEE NEUROMOTOR SYSTEM. NEUROMUSCULAR
TRANSMISSION
NEURONAL LIPIDOSES, CEREBROTENDINOUS
XANTHOMATOSIS TYPE
SEE LIPOGRANULOMATOSES. CEREBROTENDINOUS
XANTHOMATOSIS
NEURONS
SEE NERVOUS SYSTEM. NEURONS
NEUROPATHOLOGY
SEE NERVOUS DISORDERS (GENERAL)
NEUROPHARAAACOLOGICAL AGENTS
SEE ALSO NEUROTRANSMITTERS (GENERAL)
SEE ALSO NEUROTRANSMinERS BIOSYNTHESIS
ROlHL-12647-08 Inactivation of norepinephrine in vascular
tissue
ROlHL-13920-07 Expanding the role of surgery of atrial
dysrhythmias (dogs)
ROlHL-1 7993-04 0003 Ventricular dynamics from
surgically inserted markers - Effects of pharmacologic
agents on left ventricular dynamics (human)
ROlHL-18994-03 Substance P-Occurrence, pharmacology
and physiology (mammals non-human, human)
NEUROPHARAAACOLOGICAL AGENTS,
ANALGESICS
SEE ALSO PSYCHOPHARMACOLOGICAL AGENTS. NARCOTICS
SEE ALSO PURINES-PYRIMIDINES METABOLISM ERRORS,
GOUT DRUGS
R01HL-00340-29 Electrolyte disturbance in cardio-renal
disease (human, dogs, rats)
ROlHL-12971-15 Reactions of alkoloids and their analogs
NEUROPHARMACOLOGICAL AGENTS,
ANALGESICS, ANTIPYRETICS
SEE ALSO DISEASES. PATHOLOGIC PROCESSES,
INFLAMMATION, ANTIINFLAMMATORY AGENTS
" P01HL-08899-14 0026 Tolerance to respiratory gases in
health and disease - Effects of oxygen on central nervous
system functions (rats, rabbits)
ROlHL-16246-06 Immunologic studies in
postpericardiotomy syndrome (human)
NEUROPHARMACOLOGICAL AGENTS,
ANESTHETICS
POlHL-06285-18 0147 Cardiovascular-respiratory
physiology and biochemistry - Metabolic regulation of
cerebral microcirculation (cats)
*EacludM routine melhodoloo OR covert only general proiecti which preclude Indexing at the specific level.
"Oftanlad tlgnHtcantly to above lubjeet.
M Grant has subprajacts describing specific research aspects.
See Appendix for Investigator's name and grant number
" POlHL-07896-15 0030 Environmental biomedical research
program Narcosis caused by inert fitet at raited
pressures (human, animals)
** POIHL 07896 15 0056 Environmental biomedical research
program Neuromuscular blocking effects of
nondepolarizing muscular relaxants (frogs)
ROIHL 10018 II Effect of aging on beating heart cells In
culture (rats)
ROIHL 12528 10 NMR relaxation of liquid crystal tyslemi
ROIHL 13257 09 Inhalation anesthesia on myocardial
metabolism (dogs, swine, human)
ROIHL 13888 15 Regulation of respiration
POIHL 14414 07 0010 Environmental influences on
cardiorespiratory and cellular functions Pressure effects
on cardiac electrical phenomena (animals)
P60HL 15169-05 0018 Support for center for sickle cell
disease Studies on sickle cell disease (human, rats,
dogs)
** ROIHL- 15392-06 Autonomic and circulatory actions of
anesthetics (dog. cat. rabbit, monkey)
** ROIHL 1579904 Effect of anesthetics on myocardial
function (cats)
** ROIHL 17091-05 Anesthetics and microvascular response
to hemorrhage (rats)
ROIHL-19203-03 Surgical approach to congenital heart
diseases (dogs, primates)
ROlHL-20328-01 Noninvasive assessment of autonomic
cardiac control (dogs)
ROIHL 20572-02 0001 Hemodynamic relations to
metabolism in hypertension Hemodynamic and myocardial
functional studies in the SHR (rat)
** ROlHL-20754-02 Anesthetic-induced myocardial depression
(rabbits)
POIHL 21016-02 0013 Sickle cell anemia and other
hemoglobinopathies Microclrculatory response to sickle
cell treated with anti-sickling agents (rats)
R23HL-21 116-02 Mechanisms of membrane and tissue
damage in lung (dogs, rabbits)
NEUROPHARAAACOLOGICAL AGENTS,
ANESTHETICS, LOCAL
ROIHL 13306-08 Pharmacological control of cardiac
membrane currents (cattle, rabbits)
ROlHL-18711-03 Electrophysiology of heart cells (rats,
chicks)
ROlHL-21329-02 Beta-receptor regulation and cardiac
sites of drug action (cat, guinea pig, rat)
** ROlHL-21742-01 Frequency-dependent drug actions in
cardiac muscle (rabbits)
ROlHL-21812-02 Actions of drugs and ions on cardiac
membranes (rabbits, guinea pigs)
NEUROPHARMACOLOGICAL AGENTS,
ANTICONVULSANTS
ROlHL-13636-08 Effects of pharmacologic agents on heart
metabolism (human, rodents)
ROlHL-17629-03 Developmental aspects of cardiovascular
function (human, cats, rabbits)
ROlHL-19394-03 Biochemistry and regulation of taurine In
the heart (rats, guinea pigs, cats)
NEUROPHARAAACOLOGICAL AGENTS,
ANTIPARKINSON DRUGS
ROlHL-12971-15 Reactions of alkoloids and their analogs
NEUROPHARAAACOLOGICAL AGENTS,
AUTONOMIC AGENTS
SEE ALSO CARDIOVASCULAR AGENTS
SEE ALSO NEUROPHARMACOLOGICAL AGENTS. GANGLIONIC
BLOCKING AGENTS
SEE ALSO NEUROPHARMACOLOGICAL AGENTS, GANGLIONIC
STIMULATING AGENTS
SEE ALSO NEUROPHARMACOLOGICAL AGENTS,
PARASYMPATHOLYTIC
SEE ALSO NEUROPHARMACOLOGICAL AGENTS,
PARASYMPATHOMIMETIC
SEE ALSO NEUROPHARMACOLOGICAL AGENTS,
SYMPATHOLYTIC
SEE ALSO NEUROPHARMACOLOGICAL AGENTS,
SYMPATHOMIMETIC
POlHL-06285-18 0132 Cardiovascular-respiratory
physiology and biochemistry - Umbilical-placental
circulatory responses (lambs)
ROIHL-13339-08 Pharmacology of developing cardiac
tissues (chick embryo)
ROlHL-13634-08 Renal hypertension in pregnancy (sheep)
ROlHL-14832-06 Myocardial cells-Autonomic and rhythmic
mechanisms (chick embryo, rats)
** ROlHL-1 5392-06 Autonomic and circulatory actions of
anesthetics (dog, cat, rabbit, monkey)
ROlHL-17958-04 Circulatoi> effects of operant
cardiovascular control (baboons)
ROlHL-18308-03 Comprehensive studies of mucociliary
transport (dogs)
R23HL-21368-02 Perinatal cardiac electrophysiology (dogs)
NEUROPHARMACOLOGICAL AGENTS,
CENTRAUY ACTING DRUGS (GENERAL)
ROlHL-07776-15 Sudden death and cardiac arrhythmias
(human, dogs, cats)
** POlHL-12738-10 0042 Physiologic pharmacology and its
clinical applications - Centrogenic cardiac arrhythmias
(cats)
(contd)
NEU
376
NEU
P50HL-14 159-08 0018 Specialized center of research in
hypertension - Sympathetic nervous system in hypertension
(rats)
ROlHL-21799-01 Circumventricular sites of pressor action
of angiotensin I! (rats)
NEUROPHARMACOLOGICAL AGENTS,
GANGLIONIC BLOCKING AGENTS
SEE ALSO MUSCLE REUXANTS, NEUROMUSCUUR BLOCKING
AGENTS
SEE ALSO NEUROPHARMACOLOGICAL AGENTS,
PARASYMPATHOLYTIC
SEE ALSO NEUROPHARMACOLOGICAL AGENTS,
SYMPATHOLYTIC
POlHL-12738-10 0065 Physiologic pharmacology and its
clinical applications - Psychotheropeutic drugs and
cardiovascular system (human, rats)
R01HL'13e34-08 Renal hypertension in pregnancy (sheep)
ROlHL'20563-02 Restoring microcirculation after platelet
aggregation
ROlHL-22603-01 Trace metals, vascular activity and
hypertension (rats)
NEUROPHARMACOLOGICAL AGENTS,
GANGLIONIC STIMULATING AGENTS
SEE ALSO NEUROPHARMACOLOGICAL AGENTS,
PARASYMPATHOMIMETIC
SEE ALSO NEUROPHARMACOLOGICAL AGENTS,
SYMPATHOMIMETIC
ROlHL-2167301 Pathophysiology of venous changes in
hypertension (rats, rabbits, human, dogs)
NEUROPHARMACOLOGICAL AGENTS,
PARASYMPATHOLYTIC
SEE ALSO HYPERSENSITIVITY, ANTIALLERGY DRUGS,
HISTAMINE ANTAGONISTS
SEE ALSO MUSCLE RELAXANTS
POlHL-06285-18 0208 Cardiovascular-respiratory
physiology and biochemistry - Composition, properties and
turnover of pulmonary surfactant (human, animals)
R01HL10622-12 Volumes and compliance of pulmonary
circulation (human, dogs)
ROlHL-11802'10 Cardiovascular surgical research (dogs,
sheep, swine, cats, monkeys)
P50HL-15061-07 0005 Response of lung to injury - Airway
smooth muscle in health and disease (dogs, guinea pigs)
P50HL-19160-02 0001 Mucus abnormality in cystic
fibrosis - Regulation of respiratory secretions (rat, human)
P50HL-19170-02 0007 Harvard pulmonary SCOR -Chronic
diseases of the airways - Therapy effect on airway
obstruction in acute asthma (human)
ROlHL-19431-03 Regional mucociliary transport in the
human lung
ROlHL-22170-01 Factors influencing transmission at
adrenergic synpases
NEUROPHARMACOLOGICAL AGENTS,
PARASYMPATHOMIMETIC
SEE ALSO CHOLINE, ACETYLCHOLINE
SEE ALSO IMIDAZOLES, HISTAMINE
SEE ALSO MUSCLE STIMUUNTS
SEE ALSO NEUROTRANSMIHER RECEPTORS, CHOLINERGIC
RECEPTORS
POlHL-06285-18 0130 Cardiovascular-respiratory
physiology and biochemistry • Ductus arteriosus -
Morphological development (human, lambs)
' POlHL-06285-18 0189 Cardiovascular-respiratory
physiology and biochemistry - Mucociliary clearance (cats,
dogs)
POlHL-06285-18 0208 Cardiovascular-respiratory
physiology and biochemistry - Composition, properties and
turnover of pulmonary surfactant (human, animals)
POlHL-1 1310-12 0087 Mechanisms of cardiovascular
disease - Electrophysiology and electropharraacology of the
heart (dogs)
POlHL-12738-10 0108 Physiologic pharmacology and its
clinical applications - Developmental electrophysiology and
pharmacology (human, animals)
P50HL-14 153-07 0013 Johns Hopkins Lung Center-
Chronic diseases of airways ■ Pulmonary mechanics and
mediators of allergic reactions (guinea pigs, human)
ROlHL-14844-06 Mucous glycoprotein in human respiratory
epithelium (also wheat)
ROlHL-15392-06 Autonomic and circulatory actions of
anesthetics (dog, cat, rabbit, monkey)
ROlHL-15758-06 Catecholamine release in the heart
(dogs)
ROlHL-16730-03 Physiology of mucociliary transport (rats,
frogs, rabbits)
P50HL-19156-02 0004 Pulmonary SCOR -Chronic diseases
of airways - Interactions between mast cells, mediators
and nerves in canine asthma
P50HL19160-02 0001 Mucus abnormality in cystic
fibrosis - Regulation of respiratory secretions (rat, human)
P50HL-19185-02 0003 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Factors affecting formation
and release of pulmonary surfactant in fetal lambs
ROlHL-19225-02 0003 Types and mechanims of
pulmonary hypertension - Cardiopulmonary function in pigs
and rats
POl ML- 19242-02 0004 Study of vascular smooth muscle -
Cyclic nucleotide metabolism in smooth muscle cultures
(human, rats)
ROlHL-19431-03 Regional mucociliary transport in the
human lung
ROlHL-20783-02 Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
POlHL-20984-02 0005 Cellular mechanisms in cardiac
hypertrophy - Neurohumoral receptors in cardiac growth
and compensatory hypertrophy (animals)
R23HL-21368-02
ROlHL-22333-01
(rats)
R01HL-22463-02
edema (rats)
R23HL-22490-01
heart cells
R23HL-22728-01
ROlHL-23209-01
Perinatal cardiac electrophysiology (dogs)
Cellular basis of small airways function
Pinocytotic vesicles and pulmonary
Neurotransmitter receptors of cultured
Neural control of renin secretion (dogs)
Autonomic receptors of the pulmonary
vasculature (mammals)
NEUROPHARAAACOLOGICAL AGENTS,
SYMPATHOLYTIC
SEE ALSO BENZOPYRROLES, SEROTONIN INHIBITORS
SEE ALSO CARDIOVASCULAR AGENTS, ANTIHYPERTENSIVE
AGENTS
SEE ALSO CARDIOVASCULAR AGENTS, VASODILATORS
SEE ALSO PHENYLALKYLAMINES, CATECHOLAMINES
INHIBITORS
SEE ALSO RESPIRATORY DRUGS, BRONCHOCONSTRICTORS
ROlHL-03181-21 0025 Hemodynamics as applied to
surgical problems - Vascular stenosis (dogs)
ROlHL-05806-18 Analysis of antiarrhythmic agents (dogs,
rabbits)
P01HL-0e285-18 0208 Cardiovascular-respiratory
physiology and biochemistry - Composition, properties and
turnover of pulmonary surfactant (human, animals)
** POlHL-06296-18 0003 Cardiovascular and pulmonary
adaptation to stress - Human exercise studies (human,
dogs)
ROlHL-06736-18 Biogenic-mechanical factors In
microcirculation (rats, gerbils)
POlHL-06835-17 0045 Cardiovascular disease - Pressure-
volume-renin relationship in human hypertension
POlHL-07896-15 0059 Environmental biomedical research
program - Hyperoxygenation at elevated atmospheric
pressure on myocardial blood flow (dogs)
POlHL-11678-11 0031 Cardiovascular dynamics and their
control - Hypertension caused by stimulation of renal
sympathetic nerves (dogs)
ROlHL-11802-10 Cardiovascular surgical research (dogs,
sheep, swine, cats, monkeys)
ROlHL-1 1906-11 Comparative study of heart function
(cats, rats, hedgehogs, squirrels)
POlHL-12373-10 0012 Cardiopulmonary physiology and
pathophysiology - Biochemistry of the sympathetic nervous
system (rats, rabbits, pigeons)
POlHL-12738-10 0035 Physiologic pharmacology and its
clinical applications - Function and dysfunction of the
sinoatrial node (human)
** POlHL-12738-10 0133 Physiologic pharmacology and its
clinical applications - Pharmacologic antagonism of beta-
adrenergic blockade (dogs)
P50HL-14214-07 0021 Newborn lung center for hyaline
membrane disease - Development of surfactant system -
Surfactant production and release (rat. rabbit)
POlHL-14388-07 0209 Regulation of the circulation in
pathological states - Neural regulation of vascular
resistance in human hypertension
P50HL-15061-07 0005 Response of lung to injury - Airway
smooth muscle in health and disease (dogs, guinea pigs)
ROlHL-15444-06 Neonatal development of adrenergic
receptor mechanisms (pigs)
ROlHL-15498-06 Effects of physical training on heart
(rats)
R01HL-I5580-06 Humoral control of pulmonary and
systemic circulation (animals)
ROlHL-15805-06 Cerebral arterial tone and reactivity
(rabbits)
ROlHL-15985-06 Metabolic and hormonal control of
cardiac contraction
ROlHL-16022-05 Determinants of the ventilatory response
to hypoxia (goats, cats)
ROlHL-163 15-05 Analysis of interaction between CNS
vasomotor systems (cats, rats)
P50HL-17667-04 0031 Study of ischemic heart disease -
Pathophysiology in ischemic heart disease (dog, cat, rabbit,
monkey)
ROlHL-18097-04 Pathogenesis of acute renal failure (rats)
ROlHL-18579-03 Vasoactive hormones and blood pressure
regulation (dogs, rats, rabbits)
ROlHL-20563-02
aggregation
Restoring microcirculation after platelet
Coronary flow regulation by adenosine
ROlHL-20782-01
(rats, dogs)
ROlHL-21444-02 Pulmonary mechanics during postnatal
development (human)
ROlHL-21860-18 Factors influencing responses to
adrenergic drugs (guinea pigs, rats, cats)
R23HL-22309-01
immature dogs
ROlHL-22506-01
hypertensions
ROlHL-22573-01
Cardiovascular pharmacodynamics in
Hemodynamics of the clinical
Treatment of post surgical
ROlHL-22603-01 Trace metals, vascular activity and
hypertension (rats)
ROlHL-23209-01 Autonomic receptors of the pulmonary
vasculature (mammals)
ROlHL-23602-01 Physiology of renin, aldosterone and
prostaglandin (human, rats, dogs)
ROlHL-23653-01 Protection of the ischemic myocardium
(dogs)
NEUROPHARMACOLOGICAL AGENTS,
SYMPATHOLYTIC, ADRENERGIC ALPHA
POlHL-06285-18 0126 Cardiovascular-respiratory
physiology and biochemistry - Ventricular output, foramen
ovale and ductus arteriosus flows (lambs)
POlHL-06835-17 0046 Cardiovascular disease - Renin
activity during salt depletion in essential hypertension
(human)
POlHL-12738-10 0134 Physiologic pharmacology and its
clinical applications - Adenylate cyclase and cAMP
phosphodiesterase in cardiac development (dogs)
ROlHL-13375-09 Cellular potential changes causing
cardiac arrhythmias (dogs)
P50HL-14217-08 0061 Specialized center of research in
thrombosis - Pharmacology-Comparison of platelets and
vascular smooth muscle (animal)
POlHL-14388-07 0179 Regulation of the circulation in
pathological states - Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
POlHL-14388-07 0199 Regulation of the circulation in
pathological states - Adrenergic stimulation in
spontaneously hypertensive rats
POlHL-14388-07 0208 Regulation of the circulation in
pathological states - Baroreceptor reflex function in normal
and hypertensive man
ROlHL-16037-06 Molecular properties of cardiac
adrenergic receptors
** ROlHL-17897-03 Synthesis of alpha and beta adrenergic
antagonists
ROlHL-18537-04 Regional blood flow after acute
myocardial injury (dogs)
ROlHL-18607-03 Metabolic and drug studies on
experimental fat embolism (mice)
P50HL-19153-02 0003 SCOR -Pulmonary edemas-Eitology,
pathogenesis Possible inhibitors of mediator release and
pulmonary vascular response (sheep)
P50HL-19160-02 0001 Mucus abnormality in cystic
fibrosis - Regulation of respiratory secretions (rat, human)
ROlHL-20572-02 0007 Hemodynamic relations to
metabolism in hypertension - Drug effects on cardiac
function and hypertropy (rats)
R23HL-21203-02 Effect of vasoactive agents on lett-to-
right shunts (lambs)
ROlHL-22170-01 Factors influencing transmission at
adrenergic synpases
ROlHL-22547-01 Behavioral treatment of Raynaud's
disease (human)
NEUROPHARMACOLOGICAL AGENTS,
SYMPATHOLYTIC, ADRENERGIC BETA
ROlHL-05806-18 Analysis of antiarrhythmic agents (dogs,
rabbits)
POlHL-06285-18 0126 Cardiovascular-respiratory
physiology and biochemistry - Ventricular output, foramen
ovale and ductus arteriosus flows (lambs)
POlHL-06835-17 0045 Cardiovascular disease - Pressure-
volume-renin relationship in human hypertension
ROlHL-07776-15 Sudden death and cardiac arrhythmias
(human, dogs, cats)
ROlHL-08659-14 Myocardial performance and metabolism
in the newborn (sheep)
POlHL-08682-15 0017 Regulation of the cardiovascular
system - Neurally induced cardiac dysrhythmias (dog)
POlHL-08682-15 0026 Regulation of the cardiovascular
system - Hypertension-High renin vs low renin (dog)
ROIHL- 11907-08 Mechanisms of physiological responses
to exercise (human, dogs)
POlHL-12373-10 0003 Cardiopulmonary physiology and
pathophysiology - Myocardial function in man
** POIHL- 12373- 10 0013 Cardiopulmonary physiology and
pathophysiology - Effects of cardiovascular drugs on left
ventricular function (dogs)
POIHL-12738-10 0094 Physiologic pharmacology and its
clinical applications - Ventricular function and structure
(human, dogs)
POlHL-12738-10 0134
clinical applications
vasoconstriction (dogs, monkeys, human, rats)
Physiologic pharmacology and its
Adenylate cyclase and cAMP
phosphodiesterase in cardiac development (dogs)
P50HL-14192-08 0005 Specialized center of research in
hypertension - New techniques for recognition of
renovascular hypertension (human, dogs)
P50HL-14217-08 0061 Specialized center of research in
thrombosis - Pharmacology -Comparison of platelets and
vascular smooth muscle (animal)
PniHL-14388-07 0179 Regulation of the circulation in
pathological states - Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
POlHL-14388-07 0199 Regulation of the circulation in
pathological states - Adrenergic stimulation in
spontaneously hypertensive rats
POlHL-14388-07 0208 Regulation of the circulation in
pathological states - Baroreceptor reflex function in normal
and hypertensive man
(contd)
'Excludes routine methodology OR covers only general projects which preclude indexing
"Oriented significantly to above subject.
at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
NiU
377
NEU
ROIHL 1471706 Htmodynamics and htart structure
Ventiiculai overload (dons)
ROIHL 15002 07 Biocliemical phaimacology ot guanylate
cyclase in lung (cattle, rats)
ROIHL 15764 05 CAMP dependent protein kinase in
cardiac contraction (do(s)
ROIHL 15837 06 Renin and cardiac hypertroptiy in
hypertension (rats)
ROIHL 1740303 Metabolic control of cardiac output
(dogs)
ROIHL 1762903 Developmental aspects ot cardiovascular
(unction (human, cats, rabbits)
PSOHL 1764604 0014 Study of iscliemic lieart disease -
Progression of ischemic injury in conscious dogs (also
rabbits)
PSOHL 1 764604 0015 Study ot ischemic heart disease
Protecting ischemic myocardium in patients with evolving
myocardial infarction
P50HL 1764804 0014 Study of ischemic heart disease
Antidysrhythmic drugs and mammalian cardiac Purkinie
fibers (sheep, dog)
*• P50HL1766504 0002 Study ot ischemic heart disease
Reducing acute anterior myocardial infarction- Beta
adrenergic blockade (human)
P50HL17670-04 0009 Study of ischemic heart disease
Surgical treatment of localized left ventricular dyssynergy
(human, dogs)
** R01HL1789703 Synthesis of alpha and beta adrenergic
antagonists
R01HL17958-04 Circulatory effects of operant
cardiovascular control (baboons)
ROIHL'18288'04 Intraoperative protection of the
myocardium (dogs, rats)
P50HL1831803 0019 Pathogenesis and complications of
hypertension - Renin-angiotensin system in blood pressure
regulation (human, rat, dog)
ROlHL-18607-03 Metabolic and drug studies on
experimental fat embolism (mice)
R01HL-18749-03 Ventricular mechanics in the overloaded
heart (dogs)
ROlHL-191 12-03 Atherosclerosis studies (monkeys)
P50HL-19153-02 0003 SCOR -Pulmonary edemas-Eitology,
pathogenesis - Possible inhibitors of mediator release and
pulmonary vascular response (sheep)
P50HL-19156-02 0001 Pulmonary SCOR -Chronic diseases
of airways - Irritability of airways induced by epithelial
damage in healthy subjects (human)
P50HL-19160-02 0001 Mucus abnormality in cystic
fibrosis - Regulation of respiratory secretions (rat, human)
P50HL-19170-02 0003 Harvard pulmonary SCOR -Chronic
diseases of the airways - Mechanisms of bronchial
reactivity to acute and chronic airway challenge (dog)
R01HL19782-02 Pharmacologic studies on the ischemic
heart (dogs)
ROlHL-20253-02 Effects of exercise on the heart and its
blood supply (dogs)
R01HL-20610-02 Nerve growth factor and obstructive
cardiomyopathy (dogs)
ROlHL-2078302 Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
ROlHL-21221-02 Clinical antiarrhythmic and
pharmacodynamic studies
ROlHL-21742-01 Frequency-dependent drug actions in
cardiac muscle (rabbits)
** R23HL-2197301 Catecholamine metabolism and the heart
(human, guinea pigs)
ROlHL-22354-01 Alpha-adrenergic effects on heart
metabolism (rats)
R01HL-22506-01 Hemodynamics of the clinical
hypertensions
•* ROlHL-22522-01
antagonists
ROlHL-23245-01 Adrenergic receptors in pulmonary
vascular muscle (human, animal)
ROlHL-23586-06 Pharmacologic control of hypersensitivity
phenomena (human)
NEUROPHARAAACOLOGICAL AGENTS,
SYMPATHOMIMETIC
SEE ALSO ADRENAL MEDULLA HORMONES
SEE ALSO BENZOPYRROLES, SEROTONIN
SEE ALSO CARDIOVASCUUR AGENTS, VASOPRESSORS
SEE ALSO NEUROTRANSMITTERS RECEPTORS, ADRENERGIC
RECEPTORS
SEE ALSO NUTRIENT INTAKE ACTIVITY. APPETITE
DEPRESSANTS
SEE ALSO PHENYULKYLAMINES, CATECHOLAMINES
SEE ALSO PHENYULKYLAMINES. CATECHOLAMINES,
EPINEPHRINE
SEE ALSO PHENYULKYUMINES. CATECHOUMINES.
NOREPINEPHRINE
SEE ALSO RESPIRATORY DRUGS, BRONCHOCONSTRICTORS
SEE ALSO RESPIRATORY DRUGS, BRONCHODILATORS
P01HL-O6285-18 0125 Cardiovascular-respiratory
physiology and biochemistry - Myocardial function in the
fetal and neonatal lamb
P01HL-06285-18 0128 Cardiovascular-respiratory
physiology and biochemistry - Pulmonary circulation in fetal
lambs in utero
P01HL-06285-18 0208 Cardiovascular-respiratory
physiology and biochemistry - Composition, properties and
turnover of pulmonary surfactant (human, animals)
Cardioselectivity of beta-adrenoceptor
POIHI 06285 18 0209 Cardiovascular respltatory
physiology and biochemistry Metabolic studies of isolated
lung cells (human, animals)
POIHI 10342 13 0028 The integrated function ol
respiration and circulation Mediatoi release,
hemodynamics and respiratory function in anaphylaxis
(dogs)
ROIHL 10622 12 Volumes and compliance of pulmonary
circulation (human, dogs)
POIHL 11310 12 0087 Mechanisms ol cardiovascular
disease Electrophysiology and electropharmacology of the
heart (dogs)
ROIHL 1269009 Systemic and local vascular adjustment
m shock (monkeys, cats)
ROIHL 13257-09 Inhalation anesthesia on myocardial
metabolism (dogs, swine, human)
P50HL 14214-07 0021 Newborn lung center for hyaline
membrane disease Development ol surfactant system
Surfactant production and release (rat, rabbit)
P50HL 14217 08 0051 Specialized center of research in
thrombosis Microcirculation section (bat, hamster)
POIHL 1438807 0180 Regulation of the circulation in
pathological states Regulation of cerebral blood flow
(dogs, monkeys)
POIHL 14388-07 0199 Regulation of the circulation in
pathological states Adrenergic stimulation in
spontaneously hypertensive rats
POIHL 14388-07 0220 Regulation of the circulation in
pathological states Pharmacology of the coronary
circulation in man
ROlHL'14526-07 Oral contraceptives and hypertension
(rats)
ROlHL-1471306 Hypothermia and the heart (bats, guinea
pigs)
ROlHL-14832-06 Myocardial cells-Autonomic and rhythmic
mechanisms (chick embryo, rats)
P50HL-15061-07 0005 Response of lung to injury - Airway
smooth muscle in health and disease (dogs, guinea pigs)
ROlHL-15392-06 Autonomic and circulatory actions of
anesthetics (dog. cat. rabbit, monkey)
ROlHL-15444-06 Neonatal development of adrenergic
receptor mechanisms (pigs)
Left ventricular function in exercise
Physiology of mucociliary transport (rats.
ROlHL-166 56-06
(dogs)
R01HL-16730-03
frogs, rabbits)
ROlHL-17355-04 Pulmonary vascular adjustments in
circulatory collapse (dogs, rats)
ROlHL-17452-04 Depolarization induced cardiac
automaticity (human, animals)
ROlHL-17459-03
ROlHL-18019-04
(mice)
ROlHL-18020-04
ROlHL-180 50-04
Myocardial ischemia (dogs)
The endocrine kidney in hypertension
Splanchnic hemodynamics in man
Mechanisms of cardiovascular
teratogenesis (chick embryo) k embryo)
P50HL-183 18-03 0011 Pathogenesis and complications of
hypertension - Adrenergic function -Renin and
mineralocorticoid activity (human)
ROlHL-18340-04 Electron microscopy of the
juxtaglomerular apparatus (rats)
ROlHL-18517-03 Intrinsic innervation of the heart (dogs)
ROlHL-19057-03 Catecholamines and cyclic AMP in
cardiovascular system (rats, dogs)
P50HL-19156-02 0004 Pulmonary SCOR-Chronic diseases
of airways - Interactions between mast cells, mediators
and nerves in canine asthma
P50HL-191 70-02 0007 Harvard pulmonary SCOR-Chronic
diseases of the airways - Therapy effect on airway
obstruction in acute asthma (human)
P50HL-19185-02 0003 Pulmonary SCOR -Neonatal
respiratory distress syndromes - Factors affecting formation
and release of pulmonary surfactant in fetal lambs
P01HL-19242-02 0004 Study of vascular smooth muscle -
Cyclic nucleotide metabolism in smooth muscle cultures
(human, rats)
ROlHL-20371-02 Intravascular redistribution of blood
volume (dogs)
ROlHL-20572-02 0001 Hemodynamic relations to
metabolism in hypertension - Hemodynamic and myocardial
functional studies in the SHR (rat)
ROlHL-20648-01 Physical factors and coronary flow (dogs)
ROlHL-20685-02 Pituitary-adrenergic-ovarian vasomotor
interaction (dogs)
R23HL-21298-02 Coronary vasomotion (dogs, pigs)
ROlHL-21351-02 Renal and vascular control by
sympathetic ganglia (animals)
R23HL-21368-02 Perinatal cardiac electrophysiology (dogs)
R01HL-21429-02 Transport of LDL in arterial wall (human,
mammals)
ROlHL-21444-02 Pulmonary mechanics during postnatal
development (human)
ROlHL-21654-01 Autonomic determinants of arrhythmia
due to ischemia (cats)
ROlHL-21860-18 Factors influencing responses to
adrenergic drugs (guinea pigs, rats, cats)
ROlHL-22170-01 Factors influencing transmission at
adrenergic synpases
ROlHL-22225-01 Hormonal regulation of blood pressure
and blood flow (human, animals)
R23HL-22309-01 Cardiovascular pharmacodynamics in
immature dogs
ROIHl 22333 01
(rats)
ROIHI 22463 02
edema (rats)
ROIHL 22641 01
arterial reflexes (dogs)
ROIHL 22836 01
(rats)
R23HL 22972 01
(rats, hamsters)
ROIHL 2324501
Cellular basis ot imall airways lunclion
Pinocytotic vesicles and pulmonary
Ventilation, perfusion, and systemic
ogs)
The spontaneously hypertiniive hidney
Microcirculalory function in hypotension
Adrenergic receptors in pulmonary
^Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
**Oriented significantly to above subject.
vascular muscle (human, animal)
NEUROPHARMACOLOGICAL AGENTS,
SYMPATHOMIMETIC, ADRENERGIC ALPHA
POIHL 06285 18 0186 Cardiovascular respiratory
physiology and biochemistry Leukocyte hormone receptors
and cyclic nucleotides (tissue culture)
POIHL 12738-10 0108 Physiologic pharmacology and its
clinical applications Developmental electrophysiology and
pharmacology (human, animals)
ROIHL 14693 07 Survival value of physiological responses
to hypoxia (dogs)
ROIHL 1629205 0017 Surgery and nonobstructive
coronary insufficiency Cardiopulmonary resuscitation
(human)
POIHL 16910 05 0002 Regulation of the peripheral
circulation Coronary circulation (dogs)
ROIHL 18199-03 Effects of ions on vascular reactivity
ROlHL-1865703 Pharmacologic studies on neurogenic
digitalis effects (human, cats, dogs)
POIHL 18974-03 0008 Experimental neurogenic
hypertension program - Monoamines and hypertension
(rats)
P50HL 19153-02 0003 SCOR -Pulmonary edemas-Eitology,
pathogenesis - Possible inhibitors of mediator release and
pulmonary vascular response (sheep)
P50HL-19160-02 0001 Mucus abnormality in cystic
fibrosis - Regulation of respiratory secretions (rat, human)
ROlHL-2320901 Autonomic receptors of the pulmonary
vasculature (mammals)
NEUROPHARMACOLOGICAL AGENTS,
SYMPATHOMIMETIC, ADRENERGIC BETA
ROlHL-00487-29 Vasomotor tone and venous return
(human, dogs, monkeys )
ROlHL-05806-18 Analysis of antiarrhythmic agents (dogs,
rabbits)
ROlHL-05875-18 Pathologic metabolic and physiologic
studies of heart (human, dogs, cats)
POlHL-06285-18 0135 Cardiovascular-respiratory
physiology and biochemistry - Beta-adrenergic agents and
fetal cardiovascular dynamics (lambs)
P01HL-0628S-18 0186 Cardiovascular-respiratory
physiology and biochemistry - Leukocyte hormone receptors
and cyclic nucleotides (tissue culture)
ROlHL-07139-17 Cardiodynamics and metabolism of
congestive failure (human, dogs)
ROlHL-09711-13 Instantaneous blood flow in ascending
aorta (human, dogs)
POlHL-10342-13 0028 The integrated (unction of
respiration and circulation - Mediator release.
hemodynamics and respiratory function in anaphylaxis
(dogs)
ROlHL-12415-10 Evaluation of left ventricular function
(dogs, rabbits)
POlHL-12738-10 0081 Physiologic pharmacology and its
clinical applications - Ultrastructural and electrophysiologic
alteration of myocardium (human, dogs)
POlHL-12738-10 0108 Physiologic pharmacology and its
clinical applications - Developmental electrophysiology and
pharmacology (human, animals)
** POlHL-12738-10 0134 Physiologic pharmacology and its
clinical applications - Adenylate cyclase and cAMP
phosphodiesterase in cardiac development (dogs)
POlHL-13108-09 0022 Clinical heart transplantation -
Studies on cardiac receptors (human)
P50HL-14153-07 0014 Johns Hopkins Lung Center-
Chronic diseases of airways - Mediator release in asthma
(human)
ROlHL-14903-07 A new index of cardiac contractility
(human, dogs, baboons)
POlHL-14985-07 0009 Adaptation to hypoxia - Influence
of chemosensitivity on control of breathing during sleep
(human, dogs)
ROlHL-15002-07 Biochemical pharmacology of guanylate
cyclase in lung (cattle, rats)
POlHL-161 17-05 0007 Ion movements and membranes in
cardiovascular control - Physiological and molecular
properties of ionophores (dogs, rabbits)
POlHL-16910-05 0002 Regulation of the peripheral
circulation - Coronary circulation (dogs)
ROlHL-17776-04 Pulmonary mucus transport in
obstructive lung diseases (human)
** ROIHL- 17909-04 Drug treatment of vascular scleroprotein
defects (human, turkeys)
ROlHL-19057-03 Catecholamines and cyclic AMP in
cardiovascular system (rats, dogs)
** ROlHL-19115-02 Hormonal control of tracheobronchial
cyclic AMP (rats, guinea pigs)
P50HL-19153-02 0003 SCOR- Pulmonary edemas-Eitology,
pathogenesis - Possible inhibitors of mediator release and
pulmonary vascular response (sheep)
(contd)
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number
NEU
378
NEU
P50HL-19ieO-02 0001 Mucus abnormality in cystic
fibrosis - Regulation of respiratory secretions (rat, tiuman)
ROlHL-19394-03 Biochemistiy and regulation of taurine in
the tieart (rats, guinea pigs, cats)
ROlHL-19431-03 Regional mucociliary transport in tlie
human lung
R01HL-20572-02 0001 Hemodynamic relations to
metabolism in hypertension - Hemodynamic and myocardial
functional studies in the SHR (rat)
ROlHL-20572-02 0008 Hemodynamic relations to
metabolism in hypertension - Role of nervous system In
hemodynamic function
POlHL'20984-02 0001 Cellular mechanisms In cardiac
hypertrophy - Contractile proteins in cardiac hypertrophy
(rabbits, calves)
POlHL-20984-02 0005 Cellular mechanisms in cardiac
hypertrophy - Neurohumoral receptors in cardiac growth
and compensatory hypertrophy (animals)
ROlHL-21182'02 Active tension and shortening in cardiac
hypertrophy (rabbits)
R01HL-22064-02 Glycogen metabolism in anoxic diabetic
myocardium (rats)
ROlHL-22296-01 Autonomic mechanisms in man
ROlHL'22306-01 Renal catecholamines- Pathophysiology
of hypertension (dogs)
ROlHL-2241501 Mechanisms responsible for disease
severity in asthma (human)
R23HL-22669-01 Cardiovascular effects from visceral
atferents (dogs)
ROlHL-23209-01 Autonomic receptors of the pulmonary
vasculature (mammals)
ROIHL'2399001 Role of phosphoprotein in cardiac
inotropic responses
NEUROPHARMACOLOGY
SEE ALSO NERVOUS DISORDERS CHEMOTHERAPY
SEE ALSO PSYCHOPHARMACOLOGY
** ROlHL-02953-17 Autonomic and cardiovascular
pharmacology (rats, rabbits, dogs, guinea pigs)
** POlHL-07896-15 0056 Environmental biomedical research
program - Neuromuscular blocking effects of
nondepolarizing muscular relaxants (frogs)
ROlHL-08359-14 Morphopharmacology of vascular
adrenergic transmission (rabbits, rats)
ROlHL'08570-15 Pharmacologic and reflex influence on
vascular tone (dogs, rabbits)
POIHL'08682'15 0016 Regulation of the cardiovascular
system - Shifting cardiac pacemakers and AV nodal
activation (dog)
P01HL08682'15 0018 Regulation of the cardiovascular
system - Functional implications of cardiac afferent nerves
(dogs)
POlHL-08682-15 0022 Regulation of the cardiovascular
system - Blood pressure responses and preganglionic
sympathetic outflow (cat)
POlHL-10342-13 0011 The integrated function of
respiration and circulation - Control of respiration 1-
Peripheral chemoreceptor studies (cats)
" P01HL1034213 0019 The integrated function of
respiration and circulation - Cerebral circulation and
metabolism (dogs)
Physiologic pharmacology and its
Centrogenic cardiac arrhythmias
POlHL-1273810 0042
clinical applications
(cats)
POlHL-12738-10 0065
clinical applications
Physiologic pharmacology and its
Psychotheropeutic drugs and
cardiovascular system (human, rats)
ROIHL-13187'09 Central neural control of cardiovascular
function (cats)
R01HL1363608 Effects of pharmacologic agents on heart
metabolism (human, rodents)
ROlHL-16022-05 Determinants of the ventilatory response
to hypoxia (goats, cats)
R01HL1676804 The sympathetic nervous system and the
arterial wall (rabbits, pigeons)
POlHL-16878-05 0003 Control of ventilation in health
and disease • Brain stem respiratory neurons in response
mechanical/chemical loading (animal)
RO1HL17091-05 Anesthetics and microvascular response
to hemorrhage (rats)
R01HL1772403 Oral contraceptives and hypertension
(rats)
R01HL1837103 Pulmonary hypertension and ventilation
pathophysiology (dogs)
R01HL18590-03 Cerebral blood flow after cardiac arrest
(dogs, monkeys)
ROlHL-18601-01
adenosine (rats)
R01HL-18657-03 Pharmacologic studies on neurogenic
digitalis effects (human, cats, dogs)
R01HL-18795-04 Ischemic arrhythmias -Effect of
autonomic tone (dogs, rats, guinea pigs)
ROlHL-18862-02 Thirst and its contribution to edema
(dogs)
Experimental neurogenic
Monoamines and hypertension
Regulation of neurotransmitter release by
P01HL18974-03 0008
hypertension program
(rats)
POlHL-18974-03 0009
hypertension program
hydroxylase (rats)
ROIHL' 19320-03 Angiotensin neuropharmacology
Relationship to sodium
Experimental neurogenic
Biochemistry of brain tyrosine
ROlHL-19394-03 Biochemistry and regulation of taurine in
the heart (rats, guinea pigs, cats)
ROlHL-21800-01 Angiotensin effects on water intake and
excretion
** ROlHL-22170-01 Factors influencing transmission at
adrenergic synpases
R23HL-22245-02 Functional characteristics of atrial
receptors (rats)
ROlHL-236 14-02 Pharmacology of relaxation in smooth
muscle (mollusks)
NEUROPHYSIOLOGY (GENERAL)
SEE ALSO BRAIN ELECTRICAL ACTIVITY
SEE ALSO CEREBROVASCUUR SYSTEM. BLOOD-BRAIN
BARRIER
SEE ALSO CEREBROVASCULAR SYSTEM, BLOOD-
CEREBROSPINAL FLUID BARRIER
SEE ALSO ELECTROPHYSIOLOGY
SEE ALSO INFORMATION PROCESSING AND CONTROL
(NEURAL)
SEE ALSO NERVOUS SYSTEM CENTRAL, CEREBROSPINAL
FLUID FLOW
SEE ALSO NERVOUS SYSTEM CENTRAL, CEREBROSPINAL
FLUID PRESSURE
SEE ALSO NEUROENDOCRINE SYSTEMS
** ROlHL-05883-18 0005 Reflex control of resistance and
capacitance vessels - Differential blockade of medullated
and non-medullated vagal atferents in the cat
POlHL-07896-15 0052 Environmental biomedical research
program - Effects of hypoxia on cerebral function
POlHL-08682-15 0037 Regulation of the cardiovascular
system - Central nervous regulation of cardiopulmonary
mechanisms (cats)
P0IHL08899-14 0018 Tolerance to respiratory gases in
health and disease - Effects of respiratory gases at
extreme pressures (human)
** POlHL-08899-14 0066 Tolerance to respiratory gases In
health and disease - Neurophysiological effects of inert
gases in man
** POlHL-11678-11 0069 Cardiovascular dynamics and their
control - Nervous control of the cirulation (dogs)
ROlHL-12564-09 Control of respiration and blood gases
(human, dog)
R01HL12647-08 Inactivation of norepinephrine in vascular
tissue
ROlHL-12792-09 Local control of the microcirculation
(hamsters, rats)
ROlHL-13187-09 Central neural control of cardiovascular
function (cats)
R01HL1342709 Neural control of blood volume (monkeys.
dogs)
POlHL-14388-07 0183 Regulation of the circulation in
pathological states - Vasopressin In cardiovascular
regulation (dogs, rats)
** ROlHL-17689-06 Neurophysiologic studies of respiratory
control (cats)
R01HL17800-04 Pulmonary reflexes-Central pathways
(cats. dogs, rabbits)
ROlHL-18994-03 Substance P-Occurrence. pharmacology
and physiology (mammals non-human, human)
R23HL-21042-01 Cardiopulmonary reflexes and their
anatomical basis (dogs)
ROlHL-227 15-01 Neural integration of the cardiovascular
reflexes (dogs))
R23HL-22747-01 Cardiodynamics and hypertension under
cerebellar control (dogs)
NEUROPHYSIOLOGY, INTRACRANIAL PRESSURE
SEE ALSO EYE DISORDERS, PAPILLEDEMA
SEE ALSO NERVOUS SYSTEM CENTRAL, CEREBROSPINAL
FLUID PRESSURE
POlHL-11678-11 0057 Cardiovascular dynamics and their
control - Return of urine to circulation using cystico-caval
shunt (dogs)
POlHL-13851-16 Cyclotron produced isotopes in biology
and medicine (human, animals)
ROlHL-16066-05 Studies on neurogenic control of the
circulation (human, dogs)
ROlHL-17355-04 Pulmonary vascular adjustments in
circulatory collapse (dogs, rats)
POlHL-18974-03 0001 Experimental neurogenic
hypertension program - Central neural systems regulating
arterial pressure (rabbits)
R01HL-19298-03 Pulmonary hemodynamics (dogs, cats)
NEUROPHYSIOLOGY, NERVE IMPULSE
FACILITATION
POlHL-0628518 0180 Cardiovascular-respiratory
physiology and biochemistry - Vagal C-fibers and their
influence on visceral and somatic function (animals)
NEUROPHYSIOLOGY, NERVE IMPULSE
INHIBITION
POlHL-08682-15 0025 Regulation of the cardiovascular
system - Physiology of preganglionic cell bodies (cat)
NEUROPHYSIOLOGY, NERVE IMPULSE
INITIATION
ROlHL-20783-02 Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
NEUROPHYSIOLOGY, NEURAL CONDUCTION
ROlHL-12486-10 Structure-function correlation in the
atrium (rabbits)
ROIHL 16657-06
(rats)
Innervation of coronary arteries and heart
NEUROPHYSIOLOGY, NEURAL RECRUITMENT
POlHL-08682-15 0016 Regulation of the cardiovascular
system - Shifting cardiac pacemakers and AV nodal
activation (dog)
NEUROPHYSIOLOGY, NEURAL TRANSMISSION
SEE ALSO ELECTROPOTENTIALS, ACTION POTENTIALS
SEE ALSO ELECTROPOTENTIALS, EVOKED POTENTIALS
SEE ALSO ELECTROPOTENTIALS, SPIKE POTENTIAL
SEE ALSO EYE DISORDERS DIAGNOSIS, RETINOGRAPHY,
ELECTRORETINOGRAPHY*
SEE ALSO NEUROMOTOR SYSTEM, NEUROMUSCULAR
TRANSMISSION
R01HL-04651-19 Remote stimulation by radio-frequency
transmission (dogs, human)
P01HL-06285-18 0180 Cardiovascular-respiratory
physiology and biochemistry - Vagal C-fibers and their
influence on visceral and somatic function (animals)
POlHL-06285-18 0182 Cardiovascular-respiratory
physiology and biochemistry - Structure and function of
vascular chemoreceptors (cats, rats)
POlHL-07896-15 0029 Environmental biomedical research
program - Oxygen-helium diving resulting in high pressure
nervous syndrome (human, animals)
** ROlHL-0835914 Morphopharmacology of vascular
adrenergic transmission (rabbits, rats)
ROlHL-08570-15 Pharmacologic and reflex influence on
vascular tone (dogs, rabbits)
POlHL-08682-15 0018 Regulation of the cardiovascular
system - Functional implications of cardiac afferent nerves
(dogs)
ROlHL-10951-11 Neural control of the heart (dogs, rats)
POlHL-1 1310-12 0087 Mechanisms of cardiovascular
disease - Electrophysiology and electropharmacology of the
heart (dogs)
POlHL-1 1351-12 0003 Cellular and molecular
mechanisms of myocardial function - Mechanical and
electrical properties of cardiac muscle (rabbits)
ROlHL-13187-09 Central neural control of cardiovascular
function (cats)
ROlHL-13306-08 Pharmacological control of cardiac
membrane currents (cattle, rabbits)
ROlHL-17370-03 Synaptic chemistry and cardioregulation
in Limulus
ROIHL 17403-03 Metabolic control of cardiac output
(dogs)
ROlHL-17689-06 Neurophysiologic studies of respiratory
control (cats)
P50HL-1915602 0005 Pulmonary SCOR-Chronic diseases
of airways - Vagal receptors in the airway-Epithelial injury
and antigen (dog, cat, rabbit)
POlHL-19737-02 0011 Cellular and molecular aspects of
respiratory physiology - Chemical and metabolic factors on
peripheral chemoreceptor activity (cats)
ROlHL-20439-02 Effects of insulin on neurovascular
transmission (human, rats, rabbits, hamsters)
ROlHL-20564-02 Pathogenesis of peripheral arterial
disease (rats, rabbits)
POlHL-20592-02 0004 Cell biology of cardiac and
skeletal muscle - Excitation, conduction and contraction-
Modelling in Purkinje fibers
ROlHL-20800-17 Neural basis of respiratory and
vasomotor activity (cats)
ROlHL-21071-02 Mechanisms of hypertension in
coarctation of the aorta (dog)
R23HL-2 11 50-02 Regulation of airway mucous glands and
ion transport (dogs, ascaris)
ROIHL-21 195-02 Innervation of the heart-Acetylcholine
receptors (frogs)
ROlHL-22269-01 Excitation-contraction coupling in
enlarged hearts (rabbits)
ROlHL-22426-01 Initiation of the heartbeat-A voltage-
clamp study (bullfrogs, rabbits)
ROlHL-22868-01 Presynaptic regulatory mechanisms In
hypertension (rats, dogs)
NEUROPHYSIOLOGY, NEURAL TRANSMISSION,
ANTIDROMIC IMPULSES
POlHL-06285-18 0182 Cardiovascular-respiratory
physiology and biochemistiy - Structure and function of
vascular chemoreceptors (cats, rats)
POlHL-08682-15 0025 Regulation of the cardiovascular
system - Physiology of preganglionic cell bodies (cat)
ROlHL-22732-01 Central organization of cardiac afferent
nerves (cats, monkeys)
NEUROPHYSIOLOGY, REFLEX
SEE ALSO EAR, LABYRINTH. VESTIBULAR REFLEX
SEE ALSO MUSCLE FUNCTION, MUSCLE STRETCH REFLEX
SEE ALSO NERVOUS SYSTEM AUTONOMIC, AUTONOMIC
REFLEXES
SEE ALSO RESPIRATORY SYSTEM REFLEXES
SEE ALSO WATER ENVIRONMENT, DIVING REFLEX
** ROlHL-07723-15 Reflex control of vascular capacitance in
shock
** ROlHL-08570-15 Pharmacologic and reflex influence on
vascular tone (dogs, rabbits)
** POlHL-08682-15 0018 Regulation of the cardiovascular
system - Functional implications of cardiac afferent nerves
(dogs)
(contd)
'Excludes routine methodotogy OR cavers only general projects which preclude indexing at the specific level.
•"Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
^^sss^^mIHl
NEU
POIHl 113101? 0087 Mechanisms ot cardiovascular
disease Electrophysiology arid electropharmacology ot the
hearl (dogs)
POIHI 11678 11 0040 Cardiovascular dynamics and their
control Control of plasma potassium concentration (dogs)
POIHL 1310809 0021 Clinical heart transplantation
Autonomic rellei legulation ol ventricular tunclion (human)
PSOHl 14214 07 0022 Newborn lung center lor hyaline
membrane disease Functional integrity of surfactant
system Hyaline membrane disease (lamb, rat)
POIHL 1438807 018S Regulation of the circulation in
pathological states Reflex control of venous tone (human.
rabbits, dogs)
POIHL 14388 07 0204 Regulation of the circulation in
pathological states Reflex control ol vascular resistance
in spontaneously hypertensive rats
ROIHL 1664816 Integrated control of cardiovascular
activity (cats)
POIHL 1691005 0007 Regulation of the peripheral
circulation CNS Behavioral influences on circulation
(baboons)
P60HL 17269 04 0023 National heart and blood vessel
research and demonstration center Cardiovascular
pharmacology- Ischemia, shock and heart failure (dog. cat.
rat)
R01HL1837103 Pulmonary hypertension and ventilation
pathophysiology (dogs)
ROIHL 19467 03 Regulation of blood pressure (rats, dogs)
ROIHL 2066302 Regulation of skin blood flow in man
ROlHL-2080017 Neural basis of respiratory and
vasomotor activity (cats)
R23HL-2 104201 Cardiopulmonary reflexes and their
anatomical basis (dogs)
R23HL 2146202
arteries (dogs)
ROIHL 2254602
ROlHL-2256101
circulation (cats)
ROlHL-22594-01
failure (dogs)
R23HL-22669-01
afferents (dogs)
ROlHL-2271501
reflexes (dogs))
Mechanical interactions between ventricle
Baroreceptor reflex mechanisms in man
Hormonal control of mesenteric
Reflex control of the circulation in heart
Cardiovascular effects from visceral
Neural integration of the cardiovascular
NEUROPHYSIOLOGY, REFLEX, SOMATIC
REFLEXES
*♦ POlHL-06285-18 0180 Cardiovascular-respiratory
physiology and biochemistry Vagal C-fibers and their
influence on visceral and somatic function (animals)
NEUROPHYSIOLOGY, REFLEX, SPINAL REFLEXES
POlHL-08682-15 0022 Regulation of the cardiovascular
system - Blood pressure responses and preganglionic
sympathetic outflow (cat)
NEUROPIL
SEE NERVOUS SYSTEM, NEURONS. NEUROPIL
NEUROPSYCHOLOGICAL TESTS*
ROlHL-20724-01 Behavioral consequences of hypertension
(human)
NEUROPSYCHOLOGY (GENERAL)*
ROlHL-20384-09 Social stimulation. RNA and
cardiovascular disease (animals)
NEUROSURGERY
SEE ALSO BRAIN LESIONS SURGICAL
SEE ALSO CEREBROVASCUUR SURGERY
POlHL-11678-11 0031 Cardiovascular dynamics and their
control - Hypertension caused by stimulation of renal
sympathetic nerves (dogs)
ROlHL-13754-08 Postoperative thromboembolism in
surgical patients (human)
R01HL-13920-07 Expanding the role of surgery of atrial
dysrhythmias (dogs)
ROIHLI 7974-03 External pneumatic compression in deep
venous thrombosis (human)
NEUROSURGERY, DENERVATION (GENERAL)
" P01HL-06312-17 0023 Surgical cardiology - Effect of
denervation on atherosclerosis
** POlHL-06312-17 0025 Surgical cardiology - Effect of
denervation on arrhythmias and function with coronary
occlusion (dogs)
** POlHL-06312-17 0028 Surgical cardiology - Coronary flow
in the transplanted denervated heart (dogs)
POlHL-06835-17 0043 Cardiovascular disease - Left
atrial receptor activity by the sympathetic nervous system
(dogs)
POlHL-07896-15 0052 Environmental biomedical research
program ■ Effects of hypoxia on cerebral function
ROlHL-08359-14 Morphopharmacology of vascular
adrenergic transmission (rabbits, rats)
POlHL-08682-15 0011 Regulation of the cardiovascular
system - Histochemistry and ultrastructure of heart
innervation (dogs, ground squirrels)
POlHL-08682-15 0016 Regulation of the cardiovascular
system - Shifting cardiac pacemakers and AV nodal
activation (dog)
POlHL-08682-15 0033 Regulation of the cardiovascular
system - Functional and anatomical relations during
cardiac re-innervation (dog)
379
POIHI 08805 lb 0039 Regulation of ventilation and
pulmonary circulation Carotid body (cats)
POIHL 0880b lb 004/ Regulation of venlilalion and
pulmonary circulation Extracranial metabolic control of
ventilation (dogs, goats)
POIHL 11310 12 0087 Mechanisms of cardiovascular
disease Electrophysiology and electropharmacology ol the
heart (dogs)
ROIHL 11907 08 Mechanisms of physiological responses
to exercise (human, dogs)
ROIHL 1333908 Pharmacology of developing cardiac
tissues (chick embryo)
ROIHL 13666-06 Pharmacology of genesis of cardiac
rhythmicity (rats, cats)
POIHL 13737-07 0007 Assisted circulation
Determination of cardiac status by use of balloon pump
(dogs)
POlHL-1438807 0178 Regulation of the circulation in
pathological states Structural and functional
consequences of denervation (rats)
POlHL-14388-07 0185 Regulation ol the circulation in
pathological states - Reflex control of venous tone (human.
rabbits, dogs)
ROIHL 15659-05 Dynamic isolation studies of control of
respiration (human)
POlHL-15835-06 0010 Study of muscles related to heart
disease Muscle structure and reaction to in|ury (mice.
rats)
P01HL-ie9 10-05 0005 Regulation of the peripheral
circulation Control of circulation by baroreceptor and
chemoreceptor reflexes (dog. monkey)
ROlHL-1837103 Pulmonary hypertension and ventilation
pathophysiology (dogs)
ROlHL-18517-03 Intrinsic innervation of the heart (dogs)
ROlHL-19343-03 Behavioral influences on cardiac
contractility (monkeys)
ROlHL-19827-02 Role of the upper airways in the control
of breathing (human, cats, dogs)
ROlHL-20598-03 The coronary vascular response to
ischemia (dogs, pigs)
ROlHL-20793-02
function
ROlHL-21094-01
(dogs)
ROlHL-211 72-02
Phospholipids and cardiac receptor
Arterial baroreceptors and renal function
Regional oxygen consumption of heart
and other organs (animals)
ROlHL-22306-01 Renal catecholamines- Pathophysiology
of hypertension (dogs)
ROlHL-22594-01 Reflex control of the circulation in heart
failure (dogs)
NEUROSURGERY, SPINAL CORD LESIONS
SURGICAL
POlHL-06296-18 0007 Cardiovascular and pulmonary
adaptation to stress - Cardiovascular control during
isometric exercise (cats)
** POlHL-08682-15 0023 Regulation of the cardiovascular
system Cardiovascular control-Effects of spinal pathways
lesions (dog)
ROlHL-20572-02 0008 Hemodynamic relations to
metabolism in hypertension - Role of nervous system in
hemodynamic function
NEUROSURGERY, SYMPATHECTOMY
ROlHL-03181-21 0025 Hemodynamics as applied to
surgical problems - Vascular stenosis (dogs)
ROlHL-03181-21 0027 Hemodynamics as applied to
surgical problems - Hemodynamic studies of the Gl tract
(dogs)
POlHL-06835-17 0043 Cardiovascular disease - Left
atrial receptor activity by the sympathetic nervous system
(dogs)
ROlHL-16768-04 The sympathetic nervous system and the
arterial wall (rabbits, pigeons)
** ROlHL-18798-04 0003 Nervous and ionic factors in
sudden cardiac death - Left stellectomy in the prevention
of sudden death (dogs)
ROlHL-20400-03 Diabetic neuropathy and peripheral
vascular diseases (human, hamsters)
** ROlHL-20604-03 Sympathectomy-Cardiovascular and
molecular pharmacology (animals)
ROlHL-21034-01 Compensatory responses to arterial
occlusion (dogs)
ROlHL-23603-01 Morphogenesis of hypertensive vascular
disease (rats)
NEUROSURGERY, SYMPATHECTOMY,
IMMUNOSYMPATHECTOMY
SEE ALSO NERVE GROWfTH FACTOR
POlHL-14388-07 0160 Regulation of the circulation in
pathological states - Mechanism of the antihypertensive
effect of training (rats)
NEUROSURGERY, VAGOTOMY
POlHL-14388-07 0155 Regulation of the circulation in
pathological states - Cardiopulmonary afferent activity,
carotid chemo-baroreceptor reflexes
ROlHL-173 14-04 Effects of anesthesia and loading on
respiration (human, cats)
NEUROTOXINS
SEE ALSO LIVER DISORDERS. HEPATIC COMA-
ENCEPHALOPATHY
SEE ALSO TOXICOLOGY. ANIMAL POISONS. TETRODOTOXIN
NEU
SEE ALSO TOXICOLOCY. PROTO/OAl TOXIN-;. SAXIIOXIN
ROIHI 15231 Ob Mechanisms of hemodynamic changes
during digestion (dogs)
" ROIHL Ib958 06 X ray diffraclion analysis of thrombin
and neurotoxin
POIHI 1611/05 0006 Ion movements and membranes in
cardiovascular control Neuroreceptors and cellular
excitation (fish)
R23HL 21914 01 Studies of vasomotor control (rats)
NEUROTRANSMITTERS (GENERAL)
SEE ALSO ADRENAL MEDULLA HORMONES
SEE ALSO AMINO ACIDS. GAMMA AMINOBUTYRIC ACID
SEE ALSO BENZOPYRROLES. SEROTONIN
SEE ALSO CHOLINE. ACETYLCHOLINE
SEE ALSO IMIDAZOLES. HISTAMINE
SEE ALSO NEUROPHARMACOLOGICAl AGENTS. AUTONOMIC
AGENTS
SEE ALSO PHENYLALKYLAMINES. CATECHOLAMINES,
DOPAMINE
SEE ALSO PHENYLALKYLAMINES. CATECHOLAMINES,
EPINEPHRINE
SEE ALSO PHENYLALKYLAMINES, CATECHOUMINES.
NOREPINEPHRINE
ROlHL-0288822 Interrelationships of circulation and
respiration (opossum, cats)
ROIHL 05883 18 0002 Reflex control of resistance and
capacitance vessels Adenosine, adenine nucleotides and
vascular smooth muscle (dog)
POIHL 06370-17 0015 Cardiopulmonary and renal
pathology research center Pathogenesis of chemically
induced tissue injury (rats)
** ROlHL-06736-18 Biogenic-mechanical factors in
microcirculation (rats, gerbils)
ROlHL-07047 16 Comparative study of cardiac conduction
system (human, birds, mammals)
R01HL-08570-15 Pharmacologic and reflex influence on
vascular tone (dogs, rabbits)
POlHL-08682-15 0016 Regulation of the cardiovascular
system Shifting cardiac pacemakers and AV nodal
activation (dog)
POlHL-08682-15 0022 Regulation of the cardiovascular
system Blood pressure responses and preganglionic
sympathetic outflow (cat)
POlHL-08682 15 0025 Regulation of the cardiovascular
system - Physiology of preganglionic cell bodies (cat)
ROlHL-10897-12 Effects of hormones on cardiac
electrogenesis (rabbits, guinea pigs, dogs)
ROlHL-10951-11 Neural control of the heart (dogs, rats)
POlHL-11310-12 0087 Mechanisms of cardiovascular
disease - Electrophysiology and electropharmacology of the
heart (dogs)
R01HL-12e07-10 Dynamics of pulsatile blood flow (human,
dogs, rats)
ROlHL-12647-08
tissue
POlHL-12738-10 0110
clinical applications
arrhythmias (dogs)
ROlHL-13134-07 Mechanism of chemoreceptor discharge
(cats)
ROlHL-13315-08 Disposition of vasoactive hormones in
mammalian lung (rats, rabbits, human)
** ROlHL-14306-07 Quantification of arterial pressure control
(dogs)
POlHL-14388-07 0172 Regulation of the circulation in
pathological states - cAMP-dependent protein kinase from
heart and vascular smooth muscle (guinea pigs)
POlHL-14388-07 0179 Regulation of the circulation in
pathological states - Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
POlHL-14388-07 0187 Regulation of the circulation in
pathological states - Histamine and circulatory control
** POlHL-14388-07 0193 Regulation of the circulation in
pathological states - Ontogenesis of central nervous system
amines in hypertension (rats)
POlHL-14388-07 0212 Regulation of the circulation in
pathological states Role of dopamine in autonomic
activity
ROlHL-14523-07 Generation and regulation of force in
smooth muscle (animals)
ROlHL-14832-06 Myocardial cells-Autonomic and rhythmic
mechanisms (chick embryo, rats)
** ROlHL-15580-06 Humoral control of pulmonary and
systemic circulation (animals)
ROlHL-15677-06 Autonomic nervous system function in
bronchial asthma (human, guinea pig, rabbit)
** ROlHL-15758-06 Catecholamine release in the heart
(dogs)
** POlHL-161 17-05 0006 Ion movements and membranes in
cardiovascular control - Neuroreceptors and cellular
excitation (fish)
POlHL-16117-05 0008 Ion movements and membranes in
cardiovascular control - Arterial smooth muscle calcium
fluxes and contractility (rabbits)
•* ROlHL-16328-06 Membrane electrical properties of
vascular muscle (human, animals)
ROlHL-16725-03 Physiological regulation of pulmonary
surfactant (dogs, rats)
M POlHL-16878-05 Control of ventilation in health and
disease
(contd)
Inactivation of norepinephrine in vascular
Physiologic pharmacology and its
Physiology and pharmacology of
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
NEU
POlHL-16878-05 0003 Control ot ventilation in health
and disease - Brain stem respiratory neurons in response
mechanical/chemical loading (animal)
POlHL-16878-05 0004 Control of ventilation in health
and disease - Neurotransmitters in the respiratory system
(cats)
ROlHL-17853-03 Peripheral circulation in heart failure
(animals)
ROlHL-17907-04
(pigs, cats, rats)
ROlHL-18080-03
M
M
Brain regulation of cardiac arrhythmia
Neurotransmitter receptors In human
Electrophysiology of heart cells (rats,
Experimental neurogenic hypertension
Extrinsic control of Intestinal
microcirculation (dogs)
POlffL-18575-03 0001 Mechanisms of vascular changes
in hypertension - Arteries and resistance vessels in
hypertension (pigs, rats)
R01HL'1860I-01 Regulation of neurotransmitter release by
adenosine (rats)
ROlHL-18660-03
erythrocytes
ROlHL-18711-03
chicks)
POlHL-18974-03
program
POlHL-18974-03 0015 Experimental neurogenic
hypertension program - Neurochemistty core
R01HL1899403 Substance P -Occurrence, pharmacology
and physiology (mammals non-human, human)
P50HL-19160-02 0001 Mucus abnormality in cystic
fibrosis - Regulation of respiratory secretions (rat, human)
P50HL-19160-02 0002 Mucus abnormality in cystic
fibrosis - Ultrastructure, cytochemistry of pulmonary
secretion (human, rat)
POlHL-19242-02 0009 Study of vascular smooth muscle -
Electrophysiology of vascular smooth muscle (rats, chick
embryo)
ROlHL-19275-03 Characterization of collateral blood
vessels (dogs)
P01HL1971702 0037 Response of the lung to injury -
Catecholamines, prostaglandins and nucleotides in
pulmonary function (animals)
ROlHL-20177-02 Effects of erythrocyte deformability on
tissue perfusion (rats)
ROlHL-20548-02 Innervation of the lung (rats, monkeys)
POlHL-20581-01 Vascular neuroeffector mechanisms in
health and disease
" POlHL-20581-01 0001 Vascular neuroeffector
mechanisms in health and disease - Vascular neuroeffector
mechanism (rabbits)
** POlHL-20581-01 0003 Vascular neuroeffector
mechanisms in health and disease - Cerebrovascular
neuroeffector characteristics (animals)
" POlHL-20581-01 0004 Vascular neuroeffector
mechanisms in health and disease - Neuroeffector
characteristics of mesenteric and pulmonary blood vessels
(rabbits)
** POlHL-20581-01 0005 Vascular neuroeffector
mechanisms in health and disease - Changes in the
neuroeffector mechanism in hypertension (rabbits)
** POlHL-20581-01 0006 Vascular neuroeffector
mechanisms in health and disease - Neuroeffector
mechanism in arteries and veins in hypertension (human)
** POlHL-20581-01 9002 Vascular neuroeffector
mechanisms in health and disease • Biochemistry core
** ROlHL-20768-02 Mechanisms of circulatory regulation in
heart failure (guinea pigs)
** POlHL-20984-02 0005 Cellular mechanisms in cardiac
hypertrophy - Neurohumoral receptors In cardiac growth
and compensatory hypertrophy (animals)
" ROlHL-21099-02 Subcellular changes of blood vessels in
hypertension (rats)
ROlHL-21 195-02 Innervation of the heart -Acetylcholine
receptors (frogs)
POlHL-21584-02 0005 Respiratory mechanics in normal
and abnormal states - Regulation and behavior of airway
smooth muscle (human, animals)
ROlHL-22077-01 Vasoactive amine disposition in cultured
endothelium (rabbits)
R23HL-22728-01 Neural control of renin secretion (dogs)
ROlHL-22740-01 Behavior and cardiovascular disease-
Basic mechanisms (human)
** ROlHL-22977-01 Role of vasoconstrictor mechanisms in
heart failure (human, dogs)
ROlHL-23201-01 Mechanisms of hypertension (human,
rats)
NEUROTRANSMITTERS BIOSYNTHESIS
P50HL-18828-03 0008 Specialized center of research in
thrombosis - Biochemistry, physiology--Platelets and
subcellular platelet particles (human)
POlHL-18974-03 0009
hypertension program
hydroxylase (rats)
P01HL18974-03 0011
hypertension program
Experimental neurogenic
Biochemistry of brain tyrosine
Experimental neurogenic
Biochemistry and regulation of
brain tryptophane hydroxylase (rats)
P01HL18974-03 0012 Experimental neurogenic
hypertension program - Immunohistochemistry of central
monoamine neurons (rats)
ROlHL-20446-02 Autonomic neuropathy in diabetic mice
(also rats)
380
NEUROTRANSMITTERS METABOLISM
** POlHL-08682-15 0033 Regulation of the cardiovascular
system - Functional and anatomical relations during
cardiac re-innervation (dog)
ROlHL-09283-14 Pharmacology of molluscan hearts (also
rabbits)
** POlHL-11414-11 0028 Thrombosis and atherosclerosis
program - Catecholamine metabolism in the lung (rat)
** P50HL-14159-08 0018 Specialized center of research in
hypertension - Sympathetic nervous system in hypertension
(rats)
P50HL-142 17-08 0057 Specialized center of research in
thrombosis - Pharmacology-Platelet biochemistry (human,
animal)
ROlHL-15469-06 Human ventilatory adaptation (also,
dogs, rats)
ROlHL-17724-03 Oral contraceptives and hypertension
(rats)
ROlHL-17973-04 Cultured aortic endothelial cells (human.
cattle, dogs, swine)
ROlHL-18601-01 Regulation of neurotransmitter release by
adenosine (rats)
Experimental neurogenic
Monoamines and hypertension
Experimental neurogenic
Biochemistry and regulation of
** P01HL18974-03 0008
hypertension program
(rats)
P01HL18974-03 0010
hypertension program
PNMT In brain (rats)
R01HL19974-02 Psychologic-behavioral influences on
heart pathology (rats)
ROlHL-2043902 Effects of insulin on neurovascular
transmission (human, rats, rabbits, hamsters)
ROlHL-20446-02 Autonomic neuropathy in diabetic mice
(also rats)
ROlHL-23209-01 Autonomic receptors of the pulmonary
vasculature (mammals)
NEUROTRANSMITTERS RECEPTORS
ROlHL-02063-23 Biochemistry and function of lipids and
cell membranes (human, yeast, animals)
ROlHL-18601-01 Regulation of neurotransmitter release by
adenosine (rats)
** POlHL-19242-02 0007 Study of vascular smooth muscle -
NE release in and reactivity of vascular smooth muscle
(animals)
Angiotensin effects on water intake and
ROlHL-21800-01
excretion
R23HL-22490-01
heart cells
Neurotransmitter receptors of cultured
NEUROTRANSMITTERS RECEPTORS,
ADRENERGIC RECEPTORS
ROlHL-05883-18 0001 Reflex control of resistance and
capacitance vessels - Naturally occurring vasoactive
substances and the vascular neuroeffectors (dog)
POlHL-06285-18 0195 Cardiovascular-respiratory
physiology and biochemistry ■ Thyroid thermogenesis and
sodium transport (rats)
POlHL-06308-18 0039 Mechanisms and therapy of
circulatory disease - ANS in regulation of electrophysiology-
Role of cyclic nulceotides (animals)
R01HL06736-18 Biogenic-mechanical factors in
microcirculation (rats, gerblls)
** POlHL-07896-15 Environmental biomedical research
program
** POlHL-07896-15 0052 Environmental biomedical research
program - Effects of hypoxia on cerebral function
** ROlHL-08359-14 Morphopharmacology of vascular
adrenergic transmission (rabbits, rats)
POlHL-08682-15 0033 Regulation of the cardiovascular
system - Functional and anatomical relations during
cardiac re-innervation (dog)
** POlHL-10342-13 0019 The integrated function of
respiration and circulation - Cerebral circulation and
metabolism (dogs)
ROlHL-126 14-09 Microcirculatory control mechanisms and
hypertension (bats, rats)
POlHL-12738-10 0108 Physiologic pharmacology and its
clinical applications - Developmental electrophysiology and
pharmacology (human, animals)
** ROlHL-13666-06 Pharmacology of genesis of cardiac
rhythmicity (rats, cats)
** POlHL-14388-07 0163 Regulation of the circulation in
pathological states ■ Adrenergic receptors in coronary
vessels (dogs)
POlHL-14388-07 0178
pathological states
Regulation of the circulation in
Structural and functional
consequences of denervation (rats)
POlHL-14388-07 0183 Regulation of the circulation in
pathological states - Vasopressin in cardiovascular
regulation (dogs, rats)
POlHL-14388-07 0187 Regulation of the circulation in
pathological states - Histamine and circulatory control
P01HL1438807 0194 Regulation of the circulation in
pathological states - Dopamine-beta-hydroxylase localization
and release in hypertension
ROlHL-14397-07 Hypertension -Angiotensin and
prostaglandin pharmacology (animals)
ROlHL-15444-06 Neonatal development of adrenergic
receptor mechanisms (pigs)
ROlHL-15562-05 Regulation of skeletal muscle blood flow
(dogs)
Experimental neurogenic
Biochemistry of brain tyrosine
NEU
ROlHL-15607-06 Physiological control of splanchnic
circulation (dogs)
ROlHL-15805-06 Cerebral arterial tone and reactivity
(rabbits)
** POIHL-16117-05 0006 Ion movements and membranes in
cardiovascular control - Neuroreceptors and cellular
excitation (fish)
P01HL-16117-OS 0008 Ion movements and membranes In
cardiovascular control - Arterial smooth muscle calcium
fluxes and contractility (rabbits)
ROlHL-16454-03 Vascular muscle reactivity in
hypertension (human, rats)
ROlHL-17355-04 Pulmonary vascular adjustments in
circulatory collapse (dogs, rats)
** ROIHL- 17487-04 Adrenergic-vasoregulation interactions in
hypertension (human)
ROlHL-17711-05 Mechanism of hypoxic regulation of lung
circulation (rats, cats, guinea pigs)
ROlHL-17853-03 Peripheral circulation In heart failure
(animals)
ROlHL-18340-04 Electron microscopy of the
juxtaglomerular apparatus (rats)
ROlHL-18371-03 Pulmonary hypertension and ventilation
pathophysiology (dogs)
ROlHL-18601'01 Regulation of neurotransmitter release by
adenosine (rats)
ROlHL-18657-03 Pharmacologic studies on neurogenic
digitalis effects (human, cats, dogs)
** ROlHL-18660-03 Neurotransmitter receptors in human
erythrocytes
P50HL-18828-03 0008 Specialized center of research in
thrombosis ■ Biochemistry. physiology-Platelets and
subcellular platelet particles (human)
POlHL-1897403 0008 Experimental neurogenic
hypertension program - Monoamines and hypertension
(rats)
POlHL-1897403 0009
hypertension program
hydroxylase (rats)
** ROlHL-18995-04 Cardiovascular determinants of
catecholamine release (dogs)
ROlHL-19127-03 Synthesis of molecules for myocardial
imaging (rats)
" ROlHL-191 34-04 Angiotensin, prostaglandins, adrenergic
interactions (rats, rabbits)
POIHL- 19242-02 0007 Study of vascular smooth muscle -
NE release in and reactivity of vascular smooth muscle
(animals)
ROlHL-19275-03 Characterization of collateral blood
vessels (dogs)
ROlHL-20194-01
pressure (rats)
ROlHL-20542-03 Regional hemodynamics In spontaneous
hypertension (rats)
M POlHL-20581-01 Vascular neuroeffector mechanisms In
health and disease
** POlHL-20581-01 0002 Vascular neuroeffector
mechanisms in health and disease - Trophic interaction
between adrenergic nerves and vascular smooth muscle
POlHL-20581-01 0003 Vascular neuroeffector
mechanisms in health and disease - Cerebrovascular
neuroeffector characteristics (animals)
POlHL-20581-01 0005 Vascular neuroeffector
mechanisms in health and disease - Changes in the
neuroeffector mechanism in hypertension (rabbits)
ROlHL-20719-02
(cattle)
*• ROlHL-20793-02
function
** R23HL-21051-02 Adrenergic receptors and the adenylate
cyclase system (frog RBC)
R23HL-21150-02 Regulation of airway mucous glands and
ion transport (dogs, ascaris)
POlHL-21584-02 0005 Respiratory mechanics in normal
and abnormal states - Regulation and behavior of airway
smooth muscle (human, animals)
** ROlHL-21860-18 Factors influencing responses to
adrenergic drugs (guinea pigs, rats, cats)
ROlHL-21995-01 Protein phosphorylation and adrenergic
effects
** ROlHL-22077-01 Vasoactive amine disposition In cultured
endothelium (rabbits)
** ROlHL-22170-01 Factors influencing transmission at
adrenergic synpases
** ROlHL-2235401 Alpha-adrenergic effects on heart
metabolism (rats)
ROlHL'22415-01 Mechanisms responsible for disease
severity in asthma (human)
R23HL-2272801 Neural control of renin secretion (dogs)
ROlHL-23201-01 Mechanisms of hypertension (human,
rats)
** ROlHL-23209-01 Autonomic receptors of the pulmonary
vasculature (mammals)
ROlHL-23210-01 Biology of normal and hypertrophied
pulmonary vessels (cat, human)
** ROlHL-23245-01 Adrenergic receptors in pulmonary
vascular muscle (human, animal)
NEUROTRANSMITTERS RECEPTORS,
ADRENERGIC RECEPTORS, ALPHA RECEPTORS
ROlHL-02953-17 Autonomic and cardiovascular
pharmacology (rats, rabbits, dogs, guinea pigs)
(contd)
Brain catecholamines In control of blood
Cold induced pulmonary hypertension
Phospholipids and cardiac receptor
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
•'Oriented significantly to above subiect
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
NfU
POIHL 10436 13 0014 A multldisclpllnaty study ot
congenital htart disease Caidiovasculai ptiarmacology
(dog)
ROIHL 12421 10 Pathophysiology ol ciiculatory shock
(dogs, baboons)
POIHL 1273810 013!> Physiologic pharmacology and its
clinical applications Myocardial cells in tissue culture
(rats, chich embiyo)
POIHL 1310809 0017 Clinical heart transplantation
Electrophysiology ol the transplanted denervated human
heart
POIHL'1438807 0179 Regulation ot the circulation in
pathological states Cultured muscle cells and then cross
Innervation in vitro (rats, sheep)
POlHL'14388-07 0180 Regulation ot the circulation in
pathological states Regulation ol cerebral blood How
(dogs, monkeys)
POIHL 1438807 0199 Regulation ol the circulation in
pathological states Adrenergic stimulation In
spontaneously hypertensive rats
POIHL 1438807 0220 Regulation ol the circulation in
pathological states Pharmacology ol the coronary
circulation in man
R01HL1452607 Oral contraceptives and hypertension
(rats)
" ROlHL-20339-02 Vascular alphaadrenergic receptor
molecular properties
POlHL-20581-01 0001 Vascular neuroeHector
mechanisms in health and disease Vascular neuroeHector
mechanism (rabbits)
ROlHL-2095602 Early events lollowing stimulation ol
human platelets
** R23HL-22011-01 Adrenergic receptor cyclase system in
sensitized lung (rats, guinea pigs)
R23HL-2230901 Cardiovascular pharmacodynamics in
immature dogs
** ROlHL-22868-01 Presynaptic regulatory mechanisms in
hypertension (rats, dogs)
** ROlHL-22873-01 Adrenoceptor interconversion and
hormone homeostasis
NEUROTRANSMITTERS RECEPTORS,
ADRENERGIC RECEPTORS, BETA RECEPTORS
** R01HL05806-18 Analysis ol antiarrhythmic agents (dogs,
rabbits)
POlHL-06285-18 0186 Cardiovascular-respiratory
physiology and biochemistry - Leukocyte hormone receptors
and cyclic nucleotides (tissue culture)
POlHL-0630818 0025 Mechanisms and therapy of
circulatory disease - Subcellular calcium pools in the
genesis of arrhythmias (dogs)
POlHL-0631417 0055 Immunologic mechanisms in
cardiovascular disease - Genetics and cell biology
** ROlHL-10612-13 0020 Humoral factors in heart failure
and hypertension - The control of renin release in the dog
ROlHL-10942-09 Study of genetic hypertension In rats
P01HL12373-10 0012 Cardiopulmonary physiology and
pathophysiology • Biochemistry of the sympathetic nervous
system (rats, rabbits, pigeons)
P01HL1273810 0135 Physiologic pharmacology and its
clinical applications - Myocardial cells in tissue culture
(rats, chick embryo)
P01HL14388-07 0179 Regulation of the circulation in
pathological states - Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
R01HL-U832-06 Myocardial cells -Autonomic and rhythmic
mechanisms (chick embryo, rats)
R01HL14944-07 Renal vascular reactivity in hypertensive
patient
** ROlHL-16037-06 Molecular properties of cardiac
adrenergic receptors
R01HL-17555-D5 Distribution and metabolism of labeled
digitaloids (dogs, guinea pigs)
P50HL-17646-04 0014 Study of ischemic heart disease -
Progression ol ischemic injury in conscious dogs (also
rabbits)
** POIHL- 178 13-04 0008 Lung disease and the oxygenation
ol blood and tissue - Pulmonary regulation ol systemic
blood pressure (human, rabbits, rats)
RGlHL-18050-04 Mechanisms ot cardiovascular
teratogenesis (chick embryo) k embryo)
P50HL-18828-03 0002 Specialized center ol research in
thrombosis - Endothelial cell biology (human, guinea pig)
ROlHL-18976-03 Blood pressure control -Relation to
behavioral stress (human, dog)
ROlHL-19027-03 Calcium and cyclic AMP in causation ol
hypertension (rats)
** ROlHL-19423-03 Catecholamine action on the heart (cats,
rats)
ROlHL-19782-02 Pharmacologic studies on the ischemic
heart (dogs)
ROlHL-20184-02 Desensitization ol tracheal muscle to
isoproterenol (rats, rabbits)
ROlHL-20399-03 Vascular control in experimental diabetes
mellitus (dog)
** R01HL-20783-02 Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
** ROlHL-20859-02 Beta adrenergic catecholamine receptor
ROlHL-20956-02 Early events lollowing stimulation ol
human platelets
** ROlHL-21329-02 Beta-receptor regulation and cardiac
sites ol drug action (cat, guinea pig, rat)
381
ROIHL 216/0 01 Antiarrhythmic studies on 2 substituted
aminoindenes (dogs)
R23HL 22309 01 Cardiovascular pharmacodynamics in
immature dogs
R23HL 22490 01 Neurotransmitter receptors ol cultured
heart cells
•* ROIHL 2286801 Presynaptic regulatory mechanisms in
hypertension (rats, dogs)
** ROIHL 22873 01 Adrenoceptor interconversion and
hormone homeostasis
ROIHL 23013 01 Smooth muscle development in vitro
(chick embryo)
NEUROTRANSMITTERS RECEPTORS,
ADRENERGIC RECEPTORS, DOPAMINERGIC
RECEPTORS
POIHL 06314 17 0055 Immunologic mechanisms in
cardiovascular disease Genetics and cell biology
R01HL0912514 Ultrastructural cytochemistry (human,
chick)
POIHL 14388-07 0183 Regulation of the circulation in
pathological states Vasopressin in cardiovascular
regulation (dogs, rats)
POIHL 14388-07 0185 Regulation of the circulation in
pathological states - Reflex control ol venous tone (human,
rabbits, dogs)
POIHL 14388-07 0209 Regulation ol the circulation in
pathological states Neural regulation ol vascular
resistance in human hypertension
POlHL-14388-07 0211 Regulation ol the circulation in
pathological states Choline acetyltranslerase activity
(rats)
ROlHL-14832-06 Myocardial cells-Autonomic and rhythmic
mechanisms (chick embryo, rats)
POlHL-15194-07 0004 Pathophysiology ot
cardiopulmonary dyslunction - Specialized electrophysiology
libers -Electrogenic basis ol glycosides (mammals)
ROIHL 15958-06 X-ray diffraction analysis of thrombin
and neurotoxin
** ROlHL-18660-03 Neurotransmitter receptors in human
erythrocytes
POlHL-19242-02 0007 Study of vascular smooth muscle -
NE release in and reactivity ol vascular smooth muscle
(animals)
ROlHL-20194-01 Brain catecholamines in control of blood
pressure (rats)
ROlHL-20548-02 Innervation of the lung (rats, monkeys)
R23HL-21 150-02 Regulation of airway mucous glands and
ion transport (dogs, ascaris)
** ROlHL-2 11 95-02 Innervation of the heart-Acetylcholine
receptors (frogs)
POlHL-21584-02 0005 Respiratory mechanics in normal
and abnormal states - Regulation and behavior of airway
smooth muscle (human, animals)
NEUROTRANSMITTER RECEPTORS, CHOLINERGIC
RECEPTORS
POlHL-06308-18 0039 Mechanisms and therapy ot
circulatory disease - ANS in regulation ol electrophysiology-
Role ol cyclic nulceotides (animals)
ROlHL-14832-06 Myocardial cells-Autonomic and rhythmic
mechanisms (chick embryo, rats)
** ROlHL-18660-03 Neurotransmitter receptors in human
erythrocytes
** ROlHL-21195-02 Innervation ot the heart-Acetylcholine
receptors (frogs)
ROlHL-21800-01 Angiotensin effects on water intake and
excretion
ROlHL-221 70-01 Factors influencing transmission at
adrenergic synpases
** R23HL-227 75-01 Muscarinic receptors in the developing
heart (chick embryo)
ROlHL-230 13-01 Smooth muscle development in vitro
(chick embryo)
NEUTRAL LIPIDOSES, INBORN
SEE METABOLIC DISORDERS INBORN, LIPID (NEUTRAL)
STORAGE
NEUTRON RADIATION
SEE RADIATION, NEUTRON RADIATION
NEUTROPHIL LEUKOCYTES
SEE BLOOD CELLS, LEUKOCYTES, NEUTROPHILS
NEW WORLD MONKEYS
SEE MAMMALS. PRIMATES. MONKEYS AND APES
(ANTHROPOIDS. NON-HUMAN), NEW WORLD MONKEYS
(PLATYRHINES)*
NEWBORN
SEE CHILDREN. INFANT NEWBORN (BIRTH TO 4-6 WKS)
NEWCASTLE DISEASE VIRUS
SEE VIRUSES. PARAMYXOVIRUSES. NEWCASTLE DISEASE
VIRUS
NIACIN
SEE PYRIDINE CARBOXYLIC ACIDS, NICOTINIC ACID
NIACINAMIDE
SEE PYRIDINAMIOES, NICOTINAMIDE
NICKEL (COMPOUNDS)
SEE METALS, HEAVY METALS, NICKEL
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojects describing specif
See Appendix for investigator's name and
NICOTIANA
Stf CONSUMIR PRODUCIS, TOBACCO AHO TOBACCO
PRODUCTS
NICOTINAMIDE
Stf PYRIDINAMIDfS, NICOTINAMIDE
NICOTINAMIDE ADENINE DINUCLEOTIDE
(REDUCED)
SEE PYRIDINE NUCLEOTIDES, NICOTINAMIDE RIBOTIDES.
NA0(H2)
NICOTINE
SEE PYRIDINES. NICOTINE
NICOTINIC ACID
SEE PYRIDINE CARBOXYLIC ACIDS. NICOTINIC ACID
NICOTINIC RECEPTORS
SEE NEUROTRANSMinER RECEPTORS, CHOLINERGIC
RECEPTORS
NITRATES
POIHL 15835 06 0012 Study ol muscles related to heart
disease Contraction and energetics ol visceral and
vascular smooth muscles (rabbits)
ROIHL 22273 01 Oral and lung absorption ol nitroglycerin
(rats)
NITRILES
SEE CYANIDES
NITRITES, AMYL NITRITE
POlHL-14388-07 0185 Regulation ol the circulation in
pathological states - Rellex control of venous tone (human,
rabbits, dogs)
NITROARYLS
SEE ALSO ACRIOINES
SEE ALSO ALKALOIDS
SEE ALSO AZETIOINE
SEE ALSO CYCLIC AMINO ACIDS
SEE ALSO IMIDAZOLES
SEE ALSO PHENOTHIAZINES
SEE ALSO PURINES
SEE ALSO PYRIDINES
SEE ALSO THIAZINES
** ROlHL-11418-09 Poly-diaminophosphazenes
NITROARYLS, LACTAMS (GENERAL)
ROlHL-12971-15 Reactions of alkoloids and their analogs
NITROFERRICYANIDE SODIUM
SEE IRON CYANIDES. SODIUM NITROFERRICYANIDE
NITROGEN
SEE ALSO RADIOISOTOPES, NITROGEN
** POlHL-08899-14 0003 Tolerance to respiratory gases in
health and disease - Inert gas exchange in the eye
(human, dogs)
POlHL-08899-14 0022 Tolerance to respiratory gases in
health and disease - Effect ol inert gas and hydrostatic
pressures on physiological lunctions (monkey)
POlHL-08899-14 0064 Tolerance to respiratory gases in
health and disease - Narcotic effects ol inert gases on
functional systems (rats)
POlHL-08899-14 0073 Tolerance to respiratory gases in
health and disease - Biophysical mechanisms involved in
isobaric gas counterdillusion syndrome
POlHL-14414-07 0004 Environmental inlluences on
cardiorespiratory and cellular lunctions - Role ol diffusion
in gas exchange (chicken egg)
ROlHL-22406-01 Isobaric vascular bubbles and
decompression sickness (goats, models)
NITROGEN BALANCE
P50HL-1421807 0004 Pulmonary SCOR-Newborn lung
center - Metabolism ol inlants with respiratory distress
syndrome (human)
ROlHL-2 138 1-02 Amino acid metabolism in normal and
hypoxic myocardium (rabbits)
NITROGEN DIOXIDE
ROlHL-16029-05 Bio-organic chemistry of ozone, nitrogen
dioxide and tobacco smoke
ROlHL-16330-06 Aging-tissue injury and repair (rats)
ROlHL-19746-03 Proliferation and differentiation of
alveolar macrophages (mice, hamsters)
ROlHL-21009-02 Effects ol air pollutants on lung cells in
culture (rats)
NITROGEN MUSTARD
SEE HALOALKYLAMINES, MECHLORETHAMINE
NITROGEN MUSTARDS
SEE HALOALKYUMINES, NITROGEN MUSTARDS
NITROGEN OXIDES
SEE ALSO NITROSO GROUP (COMPOUNDS)
SEE ALSO NITROUS OXIDE
ROlHL-15273-06 Metabolism ol pulmonary surfactant
(human, rats)
ROlHL-15980-06 Reactions ol hemeproteins and oxygen
(cattle)
ROIHL-19488-03 Picosecond laser studies of heme-
proteins
(contd)
ic research aspects,
grant number.
NIT
ROlHL-19746-03 Proliferation and differentiation of
alveolar macrophages (mice, hamsters)
NITROGEN RADIOISOTOPES (13)
SEE RADIOISOTOPES, NITROGEN
NITROGLYCERIN
SEE TRIOSE ALCOHOLS, NITROGLYCERIN
NITROPHENOLS, 2,4-DINITROPHENOL
P01HL-088051S 0047 Regulation of ventilation and
pulmonary circulation - Extracranial metabolic control of
ventilation (dogs, goats)
ROlHL-1 740303 Metabolic control of cardiac output
(dogs)
NITROPRUSSIDE SODIUM
SEE IRON CYANIDES, SODIUM NITROFERRICYANIDE
NITROSO GROUP (COMPOUNDS)
POIHL'161 18-06 0003 Study of emphysema - Degradation
of collagen and elastin (human, hamsters, mice)
NITROUS OXIDE
Tolerance to respiratory gases in
Inert gas exchange in the eye
POlHL-0889914 0003
health and disease
(human, dogs)
POlHL-2101602 0015
hemoglobinopathies -
Beth Israel (human)
Sickle cell anemia and other
EPR study of NO derivatives of Hb
NMR
SEE CHEMISTRY, ANALYTICAL METHODS, SPECTROMETRY,
NMR*
NOISE POLLUTION
SEE PHYSICAL PROPERTIES, SOUND, NOISE POLLUTION
NOMENCLATURE
SEE INFORMATION AND COMMUNICATION, NOMENCLATURE
NONELECTROLYTES
SEE IONS, ELECTROLYTES, NONELECTROLYTES
NON-HISTONE NUCLEOPROTEINS
SEE NUCLEOPROTEINS, NONHISTONE (GENERAL)
NON.INVASIVE DIAGNOSIS (DIAGNOSTIC
TECHNIQUES)
SEE DIAGNOSTIC TESTS, NON-INVASIVE*
NON-NUTRITIONAL DISORDERS, NUTRITION
THERAPY FOR
SEE NUTRITION, NUTRITION THERAPY (NON-NUTRITIONAL
DISORDERS)
NONSPHEROCYTIC ANEMIA CONGENITAL
SEE BLOOD AND RE DISORDERS, ANEMIA HEMOLYTIC
CONGENITAL, NONSPHEROCYTIC
NORADRENALINE
SEE PHENYULKYUMINES, CATECHOUMINES.
NOREPINEPHRINE
NORBORNANES, MECAMYLAMINE
ROlHL'14092-07 Homeostatic regulation of plasma choline
(rats, dogs, chickens)
NOREPINEPHRINE
SEE PHENYULKYLAMINES, CATECHOLAMINES,
NOREPINEPHRINE
NORETHINORONE
SEE PROGESTERONE ANALOGS, NORETHINORONE
19-NORETHISTERONE
SEE PROGESTERONE ANALOGS, NORETHINORONE
NORETHYNODREL
SEE PROGESTERONE ANALOGS, NORETHYNODREL
NORMETANEPHRINE
SEE PHENYLALKYUMINES, CATECHOLAMINES,
NORMETANEPHRINE
NORMOBLASTS
SEE BLOOD CELLS, ERYTHROBLASTS AND ERYTHROID STEM
CELLS
NORMOTENSIVE HYPERALDOSTERONISM
SECONDARY TO JUXTAGLOMERULAR
HYPERPLASIA
SEE MHABOLIC DISORDERS INBORN, BARTTER'S SYNDROME
NORTOFRANIL
SEE A2EPINES, DESIPRAMINE
NOSE
SEE NASAL, NOSE
NOSEBLEED
SEE NASAL DISORDERS. EPISTAXIS
NOVOBIOCIN
SEE ANTIBIOTICS, NOVOBIOCIN
NUCLEAR ACIDIC PROTEINS
SEE NUCLEOPROTEINS, NONHISTONE (GENERAL)
382
NUCLEAR MAGNETIC RESONANCE
SEE CHEMISTRY, ANALYTICAL METHODS, SPECTROMETRY,
NMR*
NUCLEAR MEDICINE (GENERAL)
SEE RADIOISOTOPE (NUCLEAR) MEDICINE (GENERAL)
NUCLEAR MEDICINE IN DIAGNOSIS
SEE RADIODIAGNOSIS AND RADIODIAGNOSTIC METHODS,
RADIOISOTOPE DIAGNOSIS
NUCLEAR MEMBRANE
SEE CELL COMPONENTS, NUCLEAR MEMBRANE
NUCLEAR OVERHAUSER EFFECT
SEE CHEMISTRY. ANALYTICAL METHODS, SPECTROMETRY,
NMR*
NUCLEASES
P01HL-06314-17 0059 Immunologic mechanisms in
cardiovascular disease - Immunogenetic response to
streptococcal antigens in man
P01HL-063 14-17 0060 Immunologic mechanisms in
cardiovascular disease - Strept antigens and infections in
cardiovascular complications (human, animals)
NUCLEASES, CYCLIC NUCLEOTIDE
PHOSPHODIESTERASE
P50HL-14217-08 0057 Specialized center of research in
thrombosis - Pharmacology-Platelet biochemistry (human,
animaO
P50HL- 142 17-08 0058 Specialized center of research in
thrombosis - Mechanisms of induction and inhibition of
platelet reaction (human, pig)
R23HL-21189 01 Regulation of pulmonary endothelial cell
activities (human, cattle)
ROlHL-22566'01 Mesoionic purinones as
phosphodiesterase inhibitors
NUCLEASES, DEOXYRIBONUCLEASE
P50HL-I4153-07 0004 Johns Hopkins Lung Center-
Chronic diseases of airways ■ Macrophage enzymes in lung
Injury, inflammation and repair (rabbit)
NUCLEASES, ENDONUCLEASES (GENERAL)
POlHL-063 14-17 0057 Immunologic mechanisms in
cardiovascular disease - Antigens in cardiovascular disease
(human)
NUCLEASES, RIBONUCLEASE
ROlHL-14131-18 Abnormal hemoglobin syndromes
(human)
P50HL-14153-07 0004 Johns Hopkins Lung Center-
Chronic diseases of airways - Macrophage enzymes in lung
injury, inflammation and repair (rabbit)
NUCLEIC ACIO-AMINO ACID COMPLEXES
(PEPTIDE SYNTHESIS)
SEE AMINO ACYL TRNA
NUCLEIC ACID STRUCTURE
SEE NUCLEIC ACIDS STRUCTURE
NUCLEIC ACIDS
SEE ALSO NUCLEOTIDES
ROlHL-2222301 The cardio-pulmonary junction (dogs,
models)
NUCLEIC ACIDS, DNA
SEE ALSO NUCLEIC ACIDS SYNTHESIS, DNA
POlHL-031 74-23 0011 Mechanisms of acute vascular
reaction to injury - Mutagen metabolism by artery wall in
etiology of atherosclerosis (human, animals)
POlHL-06285-18 0179 Cardiovascular-respiratory
physiology and biochemistry - Regulation of myocardial cell
growth (rats, chick embryo)
POlHL-06835-17 0037 Cardiovascular disease - Cardiac
hypertrophy in spontaneously hypertensive rat
POlHL-06835-17 0041 Cardiovascular disease - Cardiac
performance in rats with renal hypertension
POlHL-06835-17 0042 Cardiovascular disease -
Myocardial hypertrophy due to renal hypertension (rats)
POlHL-06835-17 0057 Cardiovascular disease - Studies
on cardiac hypertrophy
POlHL-090 11-15 0009 A research and resource program
in blood - Control of RNA synthesis in nucleated cells
(yeast, ascites cell)
POlHL-13737-07 C031 Assisted circulation - Myocardial
ischemia-Biochemical changes (dogs)
RClHL-15026-12 Quantitative genetic control of protein
synthesis (human, primates, mammals)
POlHL-18708-03 0007 Oxygen, energy and contractility in
cardiac tissue - Surfaces, energy requirements, and
contractile proteins of cardiac cell in vitro
ROlHL-19195-03
(rats)
ROlHL-20826-02
Hormonal regulation of lung function
Megakaryocyte proliferation and its
control (mice)
ROlHL-21831-05 Determining sequences from hemoglobin
messenger RNA (mice, chickens, rabbits)
R01HL-22859-01 Effect of carbon monoxide on the
developing heart (rats)
NUCLEIC ACIDS, DNA CIRCULAR
Mitochondrial assembly and replication
Protein and RNA synthesis in heart
Electrophysiology of heart cells (rats.
Hormonal regulation of lung function
NUC
NUCLEIC ACIDS, METHYLATED RNA
** P01HL-09011-15 0021 A research and resource program
in blood - Regulation of transfer RNA methylating enzymes
(rats, E coll)
NUCLEIC ACIDS, MT DNA
** R01HL-04442-20
(fungi, wheat)
ROlHL-09172-15
muscle (rats)
ROlHL-22981-17 Membrane-associated functions in
microorganisms (bacteria, protozoa)
NUCLEIC ACIDS, RNA
SEE ALSO NUCLEIC ACIDS SYNTHESIS, RNA
SEE ALSO NUCLEOPROTEINS, RIBONUCLEOPROTEINS
POlHL-06835-17 0037 Cardiovascular disease - Cardiac
hypertrophy in spontaneously hypertensive rat
POlHL-06835-17 0057 Cardiovascular disease - Studies
on cardiac hypertrophy
POlHL-16137-05 0008 Alveolar biology - Macromolecular
events in pulmonary cells in toxic environments (animals)
ROlHL-18711-03
chicks)
ROlHL-19195-03
(rats)
** ROlHL-20384-09 Social stimulation, RNA and
cardiovascular disease (animals)
RClHL-22859-01 Effect of carbon monoxide on the
developing heart (rats)
NUCLEIC ACIDS, MRNA
SEE ALSO GENETICS, GENETIC CODING
SEE ALSO NUCLEIC ACIDS. RRNA
R01HL-04442-20 Mitochondrial assembly and replication
(fungi, wheat)
POlHL-06285-18 0194 Cardiovascular-respiratory
physiology and biochemistry - Hormonal regulation of
sodium transport-RNA synthesis (rats, toads)
P01HL-090il-15 0002 A research and resource program
in blood - Biosynthesis of fibrinogen (dogs)
POlHL-09011-15 0015 A research and resource program
in blood - Regulation of synthesis and transport of diverse
proteins in liver (rats)
** POlHL-09011 15 0019 A research and resource program
in blood - The transport mechanism of mRNA (rat, yeast.
ascites cells)
ROIHL 09172-15 Protein and RNA synthesis in heart
muscle (rats)
POlHL-14388-07 0190 Regulation of the circulation in
pathological states - Mechanisms of the renal actions of
aldosterone (rats)
ROIHL- 15026- 12 Quantitative genetic control of protein
synthesis (human, primates, mammals)
P50HL-1 5062-07 0009 Study of lipoproteins, artery wall,
and atherosclerosis - Plasma lipoprotein biosynthesis
(Rhesus monkeys)
ROlHL-15619-05 Regulation of prothrombin synthesis in
cultured cells (rats)
P60HL-16005-05 0013 Comprehensive sickle cell center -
Study of regulation of erythropoiesis in vitro (human, rat,
hamster, rabbit)
ROlHL-16364-04 Regulation of lipid biosynthesis and
transport (rats, swine, Xenopus)
ROlHL-16445-05 Regulation of plasma protein
biosynthesis (rats, rabbits)
ROlHL-16512-04 Lipoprotein metabolism and hormonal
regulation (chickens)
ROlHL-17710-04 Selective replication of hemoglobin genes
(mice, ducks, human)
ROlHL-17882-04 Regulation of HMG-COA reductase and
sterol synthesis (human, mammals)
** POlHL-20592-02 0011 Cell biology of cardiac and
skeletal muscle - Myosin and cytochrome oxidase
messenger RNAs (chicken)
ROlHL-20922-02 Control of human fetal hemoglobin
synthesis
P60HL-20985-01 0005 Northern California sickle cell
center - Molecular mechanism of alpha thalassemia-
Relation to sickle cell anemia (human)
** ROlHL-21831-05 Determining sequences from hemoglobin
messenger RNA (mice, chickens, rabbits)
** R23HL-22839-01 Cellular translation of liposomally-
delivered mRNA (human, mammals)
ROlHL-23588-01 NOV infection -Analysis at the subcellular
level (chickens)
ROlHL-23736-04 Sickle cell anemia and hemoglobin
synthesis (monkeys)
ROlHL-09172-15
muscle (rats)
Protein and RNA synthesis in heart
'Excludes routine methodotogy OR cavers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
ROlHL-24048-01
chick embryos
NUCLEIC ACIDS,
ROlHL-04442-20
(fungi, wheat)
ROlHL-21831-05 Determining sequences from hemoglobin
messenger RNA (mice, chickens, rabbits)
NUCLEIC ACIDS, TRNA
SEE ALSO AMINO ACYL TRNA
ROlHL-04442-20
(fungi, wheat)
ROlHL-09172-15
muscle (rats)
(contd)
Regulation of hemoglobin synthesis in
RRNA
Mitochondrial assembly and replication
Mitochondrial assembly and replication
Protein and RNA synthesis in heart
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
NUC
ROIHL 20388 03 Rtgulallon of protein tuinovai In diabetic
liaait (lat)
POIHL 2261901 0007 Callular mtcltanlsms ol haart
tallure Regulation ol contractile protein levels in heart
muscle (rats)
ROIHI 22651 01 Control ol protein metebolism in heart
muscle
NUCLEIC ACIDS, RNA VIRAL
SEE ALSO VIRUSES. RNA VIRUSES (GENERAL)
POIHL'11310 12 0100 Mechanisms ol cardiovascular
disease Structure and replication ot arenavirus and
Bunyamweraviruses
NUCLEIC ACIDS, UNNATURAL NUCLEIC ACIDS,
HYBRID NUCLEIC ACIDS
** P60HL 20985 01 0005 Northern Calilornia sickle cell
center Molecular mechanism ol alpha thalassemia -
Relation to sickle cell anemia (human)
NUCLEIC ACIDS INHIBITORS
POIHL 19737 02 0003 Cellular and molecular aspects of
respiratory physiology Cortisoldependent alterations in
lung type II cells (rats)
POIHL 2098402 0001 Cellular mechanisms in cardiac
hypertrophy Contractile proteins in cardiac hypertrophy
(rabbits, calves)
ROlHL-22354-01 Alphaadrenergic effects on heart
metabolism (rats)
NUCLEIC ACIDS METABOUSM
SEE ALSO NUCLEIC ACIDS REPAIR. DNA REPAIR (ENZYME)
SEE ALSO NUCLEIC ACIDS SYNTHESIS
SEE ALSO PURINES-PYRIMIDINES METABOLISM ERRORS
R01HL0695017 Red cell metabolism (human.
vertebrates)
R01HL12944 09 Enzymatic and biochemical studies on
blood cells (human)
** ROlHL-1434407 Platelet function and adenine nucleotide
metabolism (human)
ROlHL-1663704 Development and regression of cardiac
hypertrophy (rats)
** R23HL-21320-02 Cyclic nucleotide metabolism in vascular
endothelium
ROlHL-2313801
embryo)
ROlHL-23140-01
Myocardial ischemia (dogs. rats, chick
Determinants of irreversible ischemic
injury in heart (dog. rat)
NUCLEIC ACIDS REPAIR, DNA REPAIR (ENZYME)
POlHL-03174-23 0010 Mechanisms of acute vascular
reaction to injury • Search for mutagens in the human
blood (bacteria, animals)
NUCLEIC ACIDS STRUCTURE
POlHL-09011-15 0019 A research and resource program
in blood ■ The transport mechanism of mRNA (rat. yeast,
ascites cells)
R01HL15797-05 Lipid metabolism and atherosclerosis in
primates (monkeys, human, squirrels)
ROlHL-20300-02 Histone H5 and avian erythropoiesis
(chickens, rabbits)
ROlHL-21757-01 Elastin structure-DNA breathing-
Hemoglobin S gelation
NUCLEIC ACIDS STRUCTURE, NUCLEOSIDES
(TIDES) SEQUENCE
ROlHL-04442-20
(fungi, wheat)
ROlHL-20922-02
synthesis
ROlHL-21831-05
Mitochondrial assembly and replication
Control of human fetal hemoglobin
Determining sequences from hemoglobin
messenger RNA (mice, chickens, rabbits)
NUCLEIC ACIDS SYNTHESIS
SEE ALSO VIRUS DEVELOPMENT, REPLICATION
ROlHL-01813-25 Regulation of metabolism by drugs and
hormones (rats)
P01HL-06285-I8 0133 Cardiovascular-respiratory
physiology and biochemistry - Decreased uterine blood flow
and fetal development (lambs)
POlHL-06370-17 0004 Cardiopulmonary and renal
pathology research center - Lymphocytes in graft rejection
and immune surveillance (human)
ROlHL-19378-03 Relation of mitochondrial changes to
cardiac failure (dogs, rats)
POlHL-20552-02 0001 The development and regression of
cardiac hypertrophy - Biochemical events in cardiac
hypertrophy (rats)
POlHL-20592-02 0010 Cell biology of cardiac and
skeletal muscle - Mitochondrial genesis during myocardial
cell hypertrophy and hyperplasia (rats)
** POlHL-20984-02 0001 Cellular mechanisms in cardiac
hypertrophy - Contractile proteins in cardiac hypertrophy
(rabbits, calves)
R23HL-21396-02 Isolation, growth and metabolism of type
I pneumocytcs (rabbits)
NUCLEIC ACIDS SYNTHESIS, DNA
SEE ALSO NUCLEIC ACIDS REPAIR, DNA REPAIR (ENZYME)
SEE ALSO NUCLEOTIDYLTRANSFERASES. DNA
NUCLEOTIDYLTRANSFERASES
POlHL-03174-23 0010 Mechanisms of acute vascular
reaction to injury • Search for mutagens in the human
blood (bacteria, animals)
383
ROIHI 0444? 20 Mitochondrial assembly ind rapllcstlon
(fungi, wheat)
POIHI 06285 18 0178 Cardiovascular respiratory
physiology and biochemistry Biochemical regulation of
hypertrophy (rats, rabbits)
POIHL 06314 17 0067 Immunologic mechanisms in
cardiovascular disease Mitogenic and antigenic activation
of lymphocyte sub populations
R01HL0917215 Protein and RNA synthesis in heart
muscle (rats)
P50HL1421207 0016 Correlated studies of pulmonary
fibrosis Role of pulmonary alveolar macrophages in
fibrosis (human, rabbit)
" P60HI 17269 04 0020 National heart and blood vessel
research and demonstration center Nucleic acid and
protein metabolism in growth and development of heart
(rat)
** P50HL 1764804 0026 Study of ischemic heart disease
Control ol muscle cell prolileration (organ culture)
ROIHL 1771004 Selective replication of hemoglobin genes
(mice, ducks, human)
POIHL 1864503 0001 Biology of the artery wall and
atherosclerosis Primate arterial smooth muscle and
atherosclerosis
POIHL 18645-03 0005 Biology of the artery wall and
atherosclerosis Effects of atherosclerosis risk factors on
endothelium of the primate
P01HL197 17-02 0023 Response of the lung to injury ■
Postnatal lung development- Cells, connective tissue and
physiology (animals)
P01HL19717-02 0026 Response of the lung to injury ■
Protein depletion and postnatal lung development (rats)
POIHL 1971702 0027 Response of the lung to injury •
Hormone control of lung growth and development (rats)
POIHL 20993-02 0007 Population dynamics of arterial
cells in atherogenesis - Interaction of lipoproteins in
hypercholesteremia (human, swine)
ROlHL-221 19-01 Biochemistry of platelet function in
thrombosis and cell growth (rabbits)
ROlHL-22664-01 Regulation of myocardial cell growth
(rats, guinea pigs)
** R01HL-23025-01 Adaptive heart grovrth in neonates and
adults (rats)
NUCLEIC ACIDS SYNTHESIS, RNA
SEE ALSO GENETICS, GENETIC REGUUTION, GENETIC
INDUCTION-REPRESSION-DEREPRESSION,
TRANSCRIPTION
POlHL-06285-18 0178 Cardiovascular-respiratory
physiology and biochemistry - Biochemical regulation of
hypertrophy (rats, rabbits)
POlHL-06285-18 0193 Cardiovascular-respiratory
physiology and biochemistry ■ Hormonal regulation of
sodium transport -Aldosterone (rats, toads)
'* POlHL-06285-18 0194 Cardiovascular-respiratory
physiology and biochemistry - Hormonal regulation of
sodium transport-RNA synthesis (rats, toads)
** POlHL-0901115 0009 A research and resource program
in blood - Control of RNA synthesis in nucleated cells
(yeast, ascites cell)
** POlHL-0901 115 0021 A research and resource program
in blood - Regulation of transfer RNA methylating enzymes
(rats, E coll)
** ROlHL-09172-15 Protein and RNA synthesis in heart
muscle (rats)
** ROlHL-11551-11 RNA and protein synthesis in repair of
heart injury (mice, rats)
POlHL-14388-07 0190 Regulation of the circulation in
pathological states - Mechanisms of the renal actions of
aldosterone (rats)
P60HL-16005-05 0013 Comprehensive sickle cell center -
Study of regulation of erythropoiesis in vitro (human, rat,
hamster, rabbit)
ROlHL-17705-04 Kallikrein-kinin system in hypertension
(human, rats, dogs)
ROlHL-177 10-04 Selective replication of hemoglobin genes
(mice, ducks, human)
P50HL-19171-02 0010 Pulmonary SCOR-Lung injury by
childhood infections - Metabolic pathways of normal and
injured respiratory cells
POlHL-19242-02 0004 Study of vascular smooth muscle -
Cyclic nucleotide metabolism in smooth muscle cultures
(human, rats)
** P01HL19737-02 0003 Cellular and molecular aspects of
respiratory physiology - Cortisoldependent alterations in
lung type II cells (rats)
POlHL-20984-02 0006 Cellular mechanisms in cardiac
hypertrophy - Early biochemical aspects of cardiac
hypertrophy (rats)
R23HL-2 1428-02 Expression of human globin in
thalassemia (human)
ROlHL-22266-01 Production of proteases by lung cells in
culture (human, rodents, rabbits, sheep)
** ROlHL-22354-01 Alphaadrenergic effects on heart
metabolism (rats)
ROlHL-231 15-01 Regulation of active sodium transport
(frogs, rats)
ROlHL-23626-01 A study of the regulation of myocardial
hypertrophy (rats)
NUCLEOBASES
SEE ALSO FLAVINS
SEE ALSO IMIDAZOLES
NUC
SEE ALSO PURINES
SEE ALSO PYRIDINES
ROIHL 70286 02 Interventions to improve cardiac lunclion
in ischemia (dogs)
NUCLEOPHILIC SUBSTITUTION
SEE CHEMICAl REACTIONS, SUBSIIIUTION, NUCLEOPHILIC
NUCLEOPROTEINS, HISTONES
POIHL 06370 17 0004 Cardiopulmonary and renal
pathology research center Lymphocytes in graft reiection
and immune surveillance (human)
P60HL 17269 04 0020 National heart and blood vessel
research and demonstration center Nucleic acid and
protein metabolism in growth and development of heart
(rat)
ROIHL 1771004 Selective replication of hemoglobin genes
(mice, ducks, human)
POIHL 1870803 0007 Oxygen, energy and contractility in
cardiac tissue Surfaces, energy requirements, and
contractile proteins of cardiac cell m vitro
■* ROIHL 2030002 Histone H5 and avian erythropoiesis
(chickens, rabbits)
ROIHL 22039-02 Ion transport in cardiac muscle (do(s,
rodents, cattle)
NUCLEOPROTEINS, NON-HISTONE (GENERAL)
ROlHL-23626-01 A study of the regulation of myocardial
hypertrophy (rats)
NUCLEOPROTEINS, PROTAMINES
** P01HL15596-05 0019 Coagulation, fibrinolysis.
hemostasis and hepatitis Protamine assay and serine
proteases
ROlHL-19055 03 Platelet function during extracorporeal
perfusion (human, mammals)
NUCLEOPROTEINS, RIBONUCLEOPROTEINS
** P01HL09011-15 0019 A research and resource program
in blood - The transport mechanism of mRNA (rat, yeast,
ascites cells)
NUCLEOSIDE MONOPHOSPHATES CYCUC
SEE NUCLEOTIDES. NUCLEOSIDE MONOPHOSPHATES CYCLIC
NUCLEOSIDE TRIPHOSPHATE DNA
NUCLEOTIDYLTRANSFERASE
SEE NUCLEOTIDYLTRANSFERASES. DNA
NUCLEOTIDYLTRANSFERASES
NUCLEOSIDr TRIPHOSPHATE RNA
NUCLEOTIDYLTRANSFERASE
SEE NUCLEOTIDYLTRANSFERASES. RNA
NUCLEOTIDYLTRANSFERASES
NUCLEOSIDES
SEE ALSO PURINE NUCLEOSIDES
ROlHL-16490-04 Structural basis of nephron filtration
(rats, rabbits)
NUCLEOSIDES (TIDES) SEQUENCE
SEE NUCLEIC ACIDS STRUCTURE. NUCLEOSIDES (TIDES)
SEQUENCE
NUCLEOSIDYL AMINO ACIDS, S-
ADENOSYLMETHIONINE
ROlHL-20388-03 Regulation of protein turnover in diabetic
heart (rat)
S'-NUCLEOTIDASE
SEE PHOSPHOMONOESTERASES. 5 -NUCLEOTIDASE
NUCLEOTIDASES
SEE ALSO PHOSPHATASES
ROlHL-09125-14 Ultrastructural cytochemistry (human,
chick)
** ROlHL-12494-10 Continuum mechanics in biophysics
(human, animals)
ROlHL-14456-07 Lung metabolism-Enzymes in the
pulmonary circulation (human, animals)
NUCLEOTIDES
SEE ALSO NUCLEIC ACIDS
SEE ALSO PURINE NUCLEOTIDES
SEE ALSO PYRIDINE NUCLEOTIDES
SEE ALSO SUGAR NUCLEOTIDES
ROlHL-05949-18 Biochemistry of muscle contraction (rats,
rabbits)
** ROlHL-15447-06 Vascular role of prostaglandin and cyclic
nucleotides (rats)
POIHL- 15835-06 0011 Study of muscles related to heart
disease - Energetics and mechanism of muscle contraction
(frogs, rabbits)
POlHL-15835-06 0012 Study of muscles related to heart
disease - Contraction and energetics of visceral and
vascular smooth muscles (rabbits)
ROlHL-17944-03 Studies in lung preservation (dogs)
ROlHL-18601-01 Regulation of neurotransmitter release by
adenosine (rats)
POlHL-20984-02 0003 Cellular mechanisms in cardiac
hypertrophy • Fast-kinetics of myosin ATPase from normal
and hypertrophied heart (rabbits)
ROlHL-22231-02 Modulation of calcium control of cardiac
myofibrils (rats)
(contd)
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
**Oiiented significantly to above subject.
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
">■><&
NUC
NUCLEOTIDES, DEOXYRIBONUCLEOSIDE
MONOPHOSPHATES CYCLIC
R01HL-20n4-02 Collagen-platelet interaction and human
aorta collagen (human)
NUCLEOTIDES, NUCLEOSIDE MONOPHOSPHATES
CYCUC
SEE ALSO NUCLEOTIDES, DEOXYRIBONUCLEOSIDE
MONOPHOSPHATES CYCLIC
SEE ALSO PURINE NUCLEOTIDES, ADENINE NUCLEOTIDES,
AMP CYCLIC
SEE ALSO PURINE NUCLEOTIDES, GUANINE NUCLEOTIDES,
GMP CYCLIC
PDlHL-06285-18 0186 Cardiovascular-respiratory
physiology and biochemistry - Leukocyte hormone receptors
and cyclic nucleotides (tissue culture)
** P01HL06308-18 0039 Mechanisms and therapy of
circulatory disease - ANS in regulation of electrophysiology -
Role of cyclic nulceotides (animals)
M POlHL-06314-17 Immunologic mechanisms in
cardiovascular disease
** POlHL-06314-17 0052 Immunologic mechanisms in
cardiovascular disease - Role of cyclic nucleotides In
neutrophil function (human)
" POlHL-06314-17 0054 Immunologic mechanisms in
cardiovascular disease - Physiology of cell communications
(mice, frogs, guinea pigs)
POlHL-1 1310-12 0087 Mechanisms of cardiovascular
disease - Electrophysiology and electropharmacology of the
heart (dogs)
ROlHL-1 1802-10 Cardiovascular surgical research (dogs,
sheep, sviine, cats, monkeys)
ROlHL-13405-09 Regulation of lipid metabolism in the
lung (rats)
** P50HL-14214-07 0015 Newborn lung center for hyaline
membrane disease ■ Hormone effect on cyclic nucleotide
lipid synthesis in developing lung (animal)
** ROlHL-15447-06 Vascular role of prostaglandin and cyclic
nucleotides (rats)
ROlHL-15677-06 Autonomic nervous system function in
bronchial asthma (human, guinea pig, rabbit)
ROlHL-15813-05 Cardiac anoxia -Protective effect of
carbohydrate (dogs)
R01HL15985-06 Metabolic and hormonal control of
cardiac contraction
P60HL- 15996-06 0001 Cincinnati comprehensive sickle
cell center - Coagulation mechanisms in sickle cell disease
(human)
ROlHL-16445-05 Regulation of plasma protein
biosynthesis (rats, rabbits)
ROlHL-16611-04 Digitalis-receptor of the heart (guinea
pigs, rats)
ROlHL-16710-03
calcium (dogs)
ROlHL-16725-03
surfactant (dogs, rats)
POlHL-16833-04 0014 Hemoglobin and red cell system in
hemoglobinopathies - Erythrocyte membrane damage in Hb
SS disease (human)
** ROlHL-18260-04 Cyclic nucleotide metabolism in lung
tissue (cattle)
ROlHL-18711-03 Electrophysiology of heart cells (rats,
chicks)
ROlHL-18845-04 Regulation of renal circulation and salt
excretion (rats, dogs)
ROlHL-18936-02 Heart preservation and transplantation
studies (rat)
** ROlHL-18937-03 Cyclic nucleotides and calcium in
platelets (human)
** ROlHL-19148-03 Myocardial organelle lipid structure and
function (dog, rat)
ROlHL-19323-03 Studies of platelet microtubule protein
ROlHL-19325-03 Phosphodiesterase inhibition and muscle
contraction
ROlHL-19685-03 Pathogenesis of inflammation of the lung
(guinea pigs)
P01HL-19717-02 0007 Response of the lung to injury -
Cellular level studies of prostaglandin-like molecules
(cattle)
** POlHL-19717-02 0037 Response of the lung to injury -
Catecholamines, prostaglandins and nucleotides in
pulmonary function (animals)
ROlHL-19777-03 Regulation of hypersensitivity in the lung
(rats, guinea pigs, rabbits, human)
ROIHL 19819-03 Mitogen induced interstitial pneumonitis
(rabbits)
R01HL-201 14-02 Collagen-platelet interaction and human
aorta collagen (human)
POlHL-20552-02 0001 The development and regression of
cardiac hypertrophy • Biochemical events in cardiac
hypertrophy (rats)
** ROlHL-20611-02 Airway smooth muscle and cyclic
nucleotides
ROlHL-20787-02 Thromboxanes and prostaglandins-
Biochemical pharmacology (rabbits, human)
** R23HL-21189-01 Regulation of pulmonary endothelial cell
activities (human, cattle)
ROlHL-21294-02 Voltage clamp of isolated cardiac
Purkinje cells (dogs)
** R23HL-21320-02 Cyclic nucleotide metabolism in vascular
endothelium
384
ROlHL-22239-01 The molecular basis of electrical
excitability (chick embryos, rats)
ROlHL-22264-01 Regulation of contraction in vascular
smooth muscle (dogs)
Myocardial subcellular localization of
Physiological regulation of pulmonary
Neurotransmitter receptors of cultured
The spontaneously hypertensive kidney
Adaptive heart growth in neonates and
R23HL-22490-01
heart cells
ROlHL-22836-01
(rats)
** ROlHL-23025-01
adults (rats)
ROlHL-232 10-01 Biology of normal and hypertrophied
pulmonary vessels (cat, human)
ROlHL-23990-01 Role of phosphoprotein in cardiac
inotropic responses
NUCLEOTIDES, POLYNUCLEOTIDES
SEE ALSO NUCLEOTIDES. RIBOPOLYNUCLEOTIDES
R23HL-19594-01 Tropocollagen and tropoelastin uptake in
lung cells (human)
" ROlHL-21757-01 Elastin structure-DNA breathing-
Hemoglobin S gelation
NUCLEOTIDES, RIBOPOLYNUCLEOTIDES
SEE ALSO PURINE NUCLEOTIDES, ADENINE NUCLEOTIDES,
POLYADENYLIC ACID
POlHL-06285-18 0178 Cardiovascular-respiratory
physiology and biochemistry Biochemical regulation of
hypertrophy (rats, rabbits)
NUCLEOTIDYL-CYCLASES, ADENYLATE CYCLASE
POlHL-06285-18 0186 Cardiovascular-respiratory
physiology and biochemistry - Leukocyte hormone receptors
and cyclic nucleotides (tissue culture)
POlHL-06285-18 0196 Cardiovascular-respiratory
physiology and biochemistry - Hormonal regulation of
sodium transport -Epithelial cell membranes (toads)
POlHL-06296-18 0005 Cardiovascular and pulmonary
adaptation to stress - Regulation of ventricular
performance (animals)
POlHL-06308-18 0025 Mechanisms and therapy of
circulatory disease - Subcellular calcium pools in the
genesis of arrhythmias (dogs)
POlHL-06314-17 0055 Immunologic mechanisms in
cardiovascular disease - Genetics and cell biology
ROlHL-08508-15 Cardiac conductivity and automaticity
(human, dogs, rabbits)
ROlHL-08893-14 Structure and function of membrane
proteins (human)
POlHL-11414-11 0004 Thrombosis and atherosclerosis
program - Platelet function and nonthrombogenic surfaces
(human)
POlHL-12373-10 0012 Cardiopulmonary physiology and
pathophysiology - Biochemistry of the sympathetic nervous
system (rats, rabbits, pigeons)
POlHL-12738-10 0076 Physiologic pharmacology and its
clinical applications - Pediatric cardiac electrophysiology
and pharmacology (human, dogs)
POlHL-12738-10 0107 Physiologic pharmacology and its
clinical applications - Blood superfused cardiac fibers
(dogs)
POlHL-12738-10 0108
clinical applications
Physiologic pharmacology and its
Developmental electrophysiology and
pharmacology (human, animals)
POlHL-12738-10 0134 Physiologic pharmacology and its
clinical applications - Adenylate cyclase and cAMP
phosphodiesterase in cardiac development (dogs)
R01HL-12740-10 Hypocholesterolemic agents-
Stereochemistry (rats)
ROlHL-13715-08 Myocardial adenyl cyclase (rats)
ROlHL-13870-09 Control of myocardial sarcotubular
calcium stores (dogs)
P50HL-14159-08 0020 Specialized center of research in
hypertension - Renin-mineralocorticoid system in
hypertension (human, rat, dog)
P50HL-14217-08 0057 Specialized center of research in
thrombosis - Pharmacology-Platelet biochemistry (human,
animal)
P50HL-142 17-08 0058 Specialized center of research in
thrombosis - Mechanisms of induction and inhibition of
platelet reaction (human, pig)
POlHL-14388-07 0175 Regulation of the circulation in
pathological states - Functional studies of selected proteins
from cardiac muscle
R01HL-14706-07 Fetal hearts in organ culture (mice)
R01HL-15002-07 Biochemical pharmacology of guanylate
cyclase in lung (cattle, rats)
ROlHL-15696-06 Mechanism and role of cyclic GMP in
heart (animals)
ROlHL-15764-05 C-AMP dependent protein kinase in
cardiac contraction (dogs)
ROlHL-15985-06 Metabolic and hormonal control of
cardiac contraction
ROlHL-16037-06 Molecular properties of cardiac
adrenergic receptors
POlHL-161 17-05 0006 Ion movements and membranes in
cardiovascular control - Neuroreceptors and cellular
excitation (fish)
ROIHL-16666-05 Micropinocytosis in isolated capillary
endothelium
P60HL-17269-04 0003 National heart and blood vessel
research and demonstration center - Atherosclerosis -Fatty
acid metabolism in cardiovascular tissue (human, chicken)
•Excludes routine methodology OR covers only general protects which preclude indexing at the specific level.
"Oriented significantly to above subject.
NUC
ROlHL-17516-04 Role of androgen as a risk factor in
atherogenesis (human, animals)
POlHL-17813-04 0008 Lung disease and the oxygenation
of blood and tissue - Pulmonary regulation of systemic
blood pressure (human, rabbits, rats)
ROlHL-18260-04 Cyclic nucleotide metabolism in lung
tissue (cattle)
** ROlHL-18272-03 Heart adenyl cyclase complex (beef
heart)
P50HL 18318-03 0015 Pathogenesis and complications of
hypertension - Cultured smooth muscle cells and
microvessel metabolism (mammals)
ROlHL-18824-03 Mechanisms of heart failure in
myopathic hamster
POlHL-18827-02 0005 Platelet vessel wall interactions in
thrombogenesis - Platelet vessel wall interactions in
thrombogenesis (human)
ROlHL-18937-03 Cyclic nucleotides and calcium in
platelets (human)
ROlHL-19027-03 Calcium and cyclic AMP in causation of
hypertension (rats)
ROlHL-19057-03 Catecholamines and cyclic AMP in
cardiovascular system (rats, dogs)
R01HL-190e8-03 Changes in membrane properties during
erythropoiesis (chick embryo)
ROlHL-19148-03 Myocardial organelle lipid structure and
function (dog. rat)
ROlHL-19423-03 Catecholamine action on the heart (cats.
rats)
ROlHL-201 14-02 Collagen-platelet interaction and human
aorta collagen (human)
ROlHL-20544-02 Integrated regulation of myocardial
energy metabolism (rats, guinea pigs)
ROlHL-20782-01 Coronary flow regulation by adenosine
(rats, dogs)
ROlHL-20783-02 Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
ROlHL-20956-02 Early events following stimulation of
human platelets
** R23HL-21051-02 Adrenergic receptors and the adenylate
cyclase system (frog RBC)
R23HL-21189-01 Regulation of pulmonary endothelial cell
activities (human, cattle)
R23HL-21320-02 Cyclic nucleotide metabolism in vascular
endothelium
ROlHL-21329-02 Beta-receptor regulation and cardiac
sites of drug action (cat, guinea pig. rat)
R23HL-21413-02 Structure and function of platelet
calcium-binding protein (human)
ROlHL-21493-02 Contractility in cardiac failure (hamsters)
ROlHL-21568-02 Cell biology of the alveolar-capillary unit
(animals)
** R23HL-220 11-01 Adrenergic receptor cyclase system in
sensitized lung (rats, guinea pigs)
** ROlHL-22136-02 Histamine and cardiac adenyl cyclase
R23HL-22309-01 Cardiovascular pharmacodynamics in
immature dogs
R23HL-22490-01 Neurotransmitter receptors of cultured
heart cells
POlHL-22619-01 0003 Cellular mechanisms of heart
failure - Digitalis induced inotropy in myocardial ischemia
heart failure (animals)
POlHL-22619-01 0009 Cellular mechanisms of heart
failure - Sarcoplasmic reticulum in cardiac, skeletal and
smooth muscle (rabbits, dogs)
ROlHL-22828-01 Adenosine and catecholamine interaction
in the heart (rats)
ROlHL-22951-01 Studies on the affect of vitamin E on
platelets (human, rats)
ROlHL-23013-01 Smooth muscle development in vitro
(chick embryo)
R01HL-23G25-01 Adaptive heart growth in neonates and
adults (rats)
ROlHL-23161-01 0003 Biology of myocardial ischemia -
Phosphorylase coupling to myocardial sarcoplasmic
reticulum (dog)
ROlHL-23245-01 Adrenergic receptors in pulmonary
vascular muscle (human, animal)
NUCLEOTIDYL-CYCLASES, GUANYLATE CYCLASE
** POlHL-06314-17 0053 Immunologic mechanisms in
cardiovascular disease - Cellular functions controlled by
cyclic GMP (human, mice, guinea pigs)
ROlHL-13715-08 Myocardial adenyl cyclase (rats)
** ROlHL-15002-07 Biochemical pharmacology of guanylate
cyclase in lung (cattle, rats)
POlHL-161 17-05 0006 Ion movements and membranes in
cardiovascular control - Neuroreceptors and cellular
excitation (fish)
ROlHL-18260-04 Cyclic nucleotide metabolism in lung
tissue (cattle)
ROlHL-18937-03 Cyclic nucleotides and calcium in
platelets (human)
ROlHL-19423-03 Catecholamine action on the heart (cats.
rats)
ROlHL-201 14-02 Collagen-platelet interaction and human
aorta collagen (human)
R23HL-21320-02 Cyclic nucleotide metabolism in vascular
endothelium
ROlHL-22136-02 Histamine and cardiac adenyl cyclase
R23HL-22775-01 Muscarinic receptors in the developing
heart (chick embryo)
(contd)
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
NUC
ROIHL 23025 01
adults dais)
Adaptiv* htart growth in n«onal«s and
NUCLEOTIDYLTRANSFERASES, DNA
NUCLEOTIDYLTRANSFERASES
PeOHL 17269 04 0020 National t<eart and blood vessel
teseaich and demonstiation center Nucleic acid and
protein metabolism in giowtti and development ol heart
(rat)
NUCLEOTIDYLTRANSFERASES, RNA
NUCLEOTIDYLTRANSFERASES
P01HL0628S 18 0179 Cardiovascular respiratory
physiology and biochemistry Regulation of myocardial cell
growth (rats, chick embryo)
POIHI 0628b 18 0193 Cardiovascular respiratory
physiology and biochemistry Hormonal regulation ot
sodium transport Aldosterone (rats, toads)
ROIHL 09562 14 Cardiac protein synthesis, overload,
alcohol and anoxia (guinea pigs)
POIHL 1131012 0100 Mechanisms ot cardiovascular
disease Structure and replication of arenavirus and
Bunyamweraviruses
P01H113737 07 0031 Assisted circulation Myocardial
ischemia -Biochemical changes (dogs)
** POIHL 1973702 0003 Cellular and molecular aspects of
respiratory physiology Cortisoldependent alterations in
lung type II cells (rats)
POlHL-20984-02 0006 Cellular mechanisms in cardiac
hypertrophy ■ Early biochemical aspects ol cardiac
hypertrophy (rats)
ROlHL-22367 01 Estrogen receptors in very low density
lipoproteins (chicken livers)
•* ROIHL 23626-01 A study of the regulation of myocardial
hypertrophy (rats)
NUCLEUS-CYTOPLASM VOLUME RELATIONSHIPS
SEE CELL VOLUME
NURSE PRACTITIONERS
SEE HEALTH SCIENCES PROFESSIONS, NURSE
PRACTITIONERS
NURSERY
SEE HOSPITALS. NURSERY
NURSES
SEE HEALTH SCIENCES PROFESSIONS. NURSES
NURSING
SEE HEALTH SCIENCES PROFESSIONS. NURSES
NURSING EDUCATION
SEE EDUCATION. HEALTH OCCUPATIONS. NURSING
NURSING SCHOOLS
SEE EDUCATION. HEALTH OCCUPATIONS. NURSING
NUTRIENT INTAKE ACTIVITY (GENERAL)
ROIHL- 19084-03 Structure and function of serum
lipoproteins (human)
ROlHL-19839-09 Factors in youth predisposing to chronic
diseases (former college students)
NUTRIENT INTAKE ACTIVITY, APPETITE
DEPRESSANTS
SEE ALSO NUTRIENT INTAKE DISORDERS. APPETITE
DISORDERS. ANOREXIA
ROIHL 22532-01 Inhibitors of cholesterol biosynthesis
(rats, mice, yeast)
NUTRIENT INTAKE ACTIVITY, DRINKING
BEHAVIOR (WATER)
SEE ALSO ALCOHOLISM - DRINKING. ALCOHOL CONSUMPTION
SEE ALSO BRAIN. DRINKING REGUUTORY CENTERS
POlHL-14388-07 0156 Regulation of the circulation in
pathological states - Blood pressure with drinking to
intracranial angiotensin II injections (rats)
ROlHL-17958-04 Circulatory effects of operant
cardiovascular control (baboons)
ROlHL-19320-03 Angiotensin neuropharmacology-
Relationship to sodium
NUTRIENT INTAKE ACTIVITY, FEEDING (EATING)
BEHAVIOR
ROIHLI 1901-12 0020 Effects of metabolic surgery on
the hyperlipidemias - Jejunoileal bypass-Endogenous
animal model of obesity (rats)
ROlHL-15174-06 CV disease epidemiology-Second
generation studies (human)
ROlHL-20910-02 The alternative diet for coronary disease
prevention (human)
NUTRIENT INTAKE ACTIVITY, SALT INTAKE
SEE ALSO NUTRITION. DIET THERAPEUTIC. SALT RESTRICTED
ROlHL-02493-22 Kidney function in experimental heart
failure (dogs, rats)
ROlHL-10612-13 0021 Humoral factors in heart failure
and hypertension - The control of aldosterone secretion
(dogs)
P01HL-1I678-11 0040 Cardiovascular dynamics and their
control - Control of plasma potassium concentration (dogs)
POlHL-11678-11 0064 Cardiovascular dynamics and their
control - Renal medulla-Control of renal hemodynamics.
electrolyte excretion (dogs)
385
POIHl 116/8 11 0065 Cardiovascular dynamics and then
control Body fluid volumes in the gencMS of hypertension
(dogs)
ROIHI 13929 06 Single nephron response to chronic
obstruction (frogs, rats)
P50HI 1423007 0088 A/S SCOR lipids, atherosclerosis
and thrombosis Coronary risk factors in school children
The Muscatine study
ROIHI 14306 07 Quantification of arterial pressure control
(dogs)
POIHL 1438807 0195 Regulation of the circulation in
pathological states General review of potential
pathophysiologic factors in spontaneous hypertension
ROIHL 1491306 Hypertension Genetic influence of kidney
(rats)
ROIHL 1583905 Physiological role of isorenin and
kallikrein (animals)
ROIHL 16489-04 Renal prostaglandins Synthesis and
function (human, dogs, rats)
ROIHL 1649604 Prostaglandins and renin experimental
hypertension (rabbits)
ROlHL-17366-05 Mechanisms in the production of renal
hypertension (rabbits, dogs)
ROIHL 1745804 Renal control of sodium excretion (rats)
M POlHl-17871 04 Kidney, sodium, cardiac output, arterioles
and hypertension
POlHL-17871-04 0013 Kidney, sodium, cardiac output,
arterioles and hypertension Perfusion pressure and renal
sodium excretion (rats)
ROIHL 17902-04 Mammalian renal microcirculation
(hamsters)
P50HL-18323-04 0042 SCOR hypertension center Blood
viscosity and blood volume in hypertensive disease
(human, dog)
P50HL 18323-04 0045 SCOR hypertension center -
Laboratory programs -Prorenin (human)
ROlHL-18579-03 Vasoactive hormones and blood pressure
regulation (dogs, rats, rabbits)
ROlHL-18862-02 Thirst and its contribution to edema
(dogs)
ROlHL-19229-02 Prostaglandins and hypertension (human.
rats, dogs, rabbits)
POlHL-19242-02 0007 Study of vascular smooth muscle -
NE release in and reactivity of vascular smooth muscle
(animals)
POlHL-19242-02 0008 Study of vascular smooth muscle -
NE release in and reactivity of vascular smooth muscle
(rats)
ROlHL-19251-03 An index of sympathetic activity in
hypertension (rats)
ROlHL-19279-03 Intracellular action of aldosterone in
hypertension (human, rats)
** P50HL-19362-02 0012 A/S SCOR -Atherosclerosis in
nonhuman primates - Induction of chronic hypertension by
salt loading (baboon)
ROlHL-19428-03 Role of angiotensin sensitivity in renin
release (human)
R01HL19825-02 Renin-volume interactions in coarctation
hypertension (dogs)
ROlHL-19922-03 Childhood determinants of blood pressure
R01HL19929-03 High blood pressure in the young.
prevalence and precursors (human)
ROlHL-20124-02 Coronary risk factors (human)
ROlHL-21099-02 Subcellular changes of blood vessels in
hypertension (rats)
ROlHL-21435-02 Control, cardiovascular and renal effects
of potassium (dogs)
ROlHL-23602-01 Physiology of renin, aldosterone and
prostaglandin (human, rats, dogs)
NUTRIENT INTAKE ACTIVITY, THIRST
** POlHL-11678-11 0027 Cardiovascular dynamics and their
control - Vasopressin and thirst in control of body fluid
volumes and osmolality (dogs)
POlHL-11678-11 0058 Cardiovascular dynamics and their
control - Overall control of the circulation-Computer
analysis
** ROlHL-18862-02 Thirst and its contribution to edema
(dogs)
** ROlHL-21799-01 Circumventricular sites of pressor action
of angiotensin II (rats)
** ROlHL-21800-01 Angiotensin effects on water intake and
excretion
NUTRIENT INTAKE DISORDERS, APPETITE
DISORDERS, ANOREXIA
SEE ALSO NUTRIENT INTAKE ACTIVITY, APPETITE
DEPRESSANTS
ROlHL-211 17-01 Altitude adaptation in chronic lung
disease (human)
NUTRITION (GENERAL)
SEE ALSO GROVriH MEDIA
ROlHL-l 50 13-07 Lung oxidative metabolism and energy
production (rodents, rabbits)
POlHL-19242-02 0001 Study of vascular smooth muscle -
Energy metabolism and protein turnover in vascular smooth
muscle (rats)
ROlHL-19859-03 Epidemiological studies, precursors of
hypertension (human)
ROlHL-19864-03 0003 Blood pressure of children and
young adults - Heart rate and blood pressure-Consistency
in infancy (human)
NUT
ROIHI 22022 01 Retpiralory muscle dy»lunction in
respiratory failure (human)
NOIHV 82919 00 Development of percutsnioui energy
transmission \yslem5
NUTRITION, DEVELOPMENTAL NUTRITION
SEE AISONUIRIIION, MAIFRNAI M lAI NUIHHION
P50HI 15103 07 0001 A/S SCOR Early natural history of
arteriosclerosis Clinical research Bogalusa heart study
(children)
*• P50HL 19362 02 0001 A/S SCOR Atherosclerosis in
nonhuman primates Effects of infant nutrition on
atherosclerosis (baboons)
•* P50HL 19362 02 0002 A/S SCOR Atherosclerosis in
nonhuman primates Infant caloric intake, adipose tissue
development and atherosclerosis (baboon)
NUTRITION, DIET
ROIHL 01803 23 0011 Arteriosclerosis, glomerulonephritis,
rheumatic fever Immunopathologic consequences of
cigarette smoking (human, rabbits, plants)
P01HL06285 18 0179 Cardiovascular respiratory
physiology and biochemistry Regulation of myocardial cell
growth (rats, chick embryo)
ROIHL 09911-12 Hormonal and dietary modification of
NaCl toxicity (rats) mice)
POlHL-11414 11 0028 Thrombosis and atherosclerosis
program Catecholamine metabolism in the lung (rat)
ROIHL 11901 12 0012 Effects of metabolic surgery on
the hypeMipidemias Ileal bypass -Animal atherosclerosis
implications (pigeons, dogs, rabbits)
ROIHL 1190708 Mechanisms of physiological responses
to exercise (human, dogs)
P01HL13262-07 0024 Arterial wall in atherosclerosis
Serial ocular changes in arteriosclerosis and hypertension
P50HL-15103-07 0001 A/S SCOR -Early natural history of
arteriosclerosis - Clinical research -Bogalusa heart study
(children)
POlHL-161 18-06 0003 Study of emphysema - Degradation
of collagen and elastin (human, hamsters, mice)
ROlHL-16658-05 Intrarenal regulation of sodium
reabsorption
ROlHL-16828-04 Gradient and transport of oxygen in
tissue and organs (mammals)
ROlHL-17463-03 Composition and structure of plasma
lipoproteins (human, rabbits)
POlHL-18575-03 0005 Mechanisms of vascular changes
in hypertension - Renin synthesis in normotensive and
hypertensive pigs (also rats, dogs)
ROlHL-18610-03 Early intervention of age related arterial
changes (pigeon)
ROlHL-18723-03 Genetic heterogeneity of acid lipase-
Atherosclerosis (human)
** ROlHL-20005-03 Factors in blood pressure levels of
children
ROlHL-20159-03 Genetic epidemiology of precursors of
hypertension (human)
ROlHL-20426-03 Myocardial function in diabetes mellitus
(dog, rat)
ROlHL-20483-03 Sterol balance and cholesterol absorption
in diabetics (human)
ROlHL-20539-03 Blood glucose, hemoglobin Ale, and
diabetic vascular disease (human)
ROlHL-21307-01
population
Risk reduction and exercise fitness in a
Stanford five city multifactor risk
R18HL-21906-01
reduction study
ROlHL-22121-02 Oyslipoproteinemia in diabetes and
vascular disease (human)
ROlHL-22298-02 Origins of hypertension (human)
R01HL-22783-01 Hemodynamic induction of intimal
fibromuscular lesion
NOlHV-12157-14 Lipid research clinic (human)
NUTRITION, DIET, FASTING
SEE ALSO DRUGS, PHARMACOLOGY, BIOAVAIUBILITY
SEE ALSO NUTRITIONAL ABNORMALITIES, STARVATION
ROlHL-06221-17 Composition and structure of plasma
lipoproteins (human, turkeys, baboons)
ROlHL-12085-10 Lipoprotein-carbohydrate metabolism
(human, rats)
ROlHL-1870503 Regulation of plasma triglyceride
metabolism (rats)
ROlHL-22123-02 The role of the red cell in diabetic
atherosclerosis (human)
ROlHL-22812-01 Regulation of hepatic production of HDL
(rats)
NUTRITION, DIET, VEGETARIANISM
ROlHL-1530807 Assays for peptides of lipoproteins
(human)
NUTRITION, DIET PATHOGENIC
NOlHI-32926-10 Analysis of lipoproteins (animals)
** R01HL-01803-23 0010 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Atherosclerosis induction -Graft rejection
and hypercholesterolemia (rabbits)
** ROlHL-01803-23 0015 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Immunologic endothelial injury and lipid
diet atherosclerosis (rabbits, monkey)
ROlHL-03299-21
(rats, rabbits)
ROlHL-05209-18
Dietary effects on cholesterol metabolism
Lipid metabolism (monkeys)
(contd)
'Excludes routine methodology OR covers only general proiects which preclude indexing at the specific level
**Onented significantty to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigators name and grant number.
NUT
POlHL-06312-17 0021 Surgical cardiology - Cardiac
IranspiantationEtfect of immunosuppression on
atherogenesis (monkeys)
POlHL-06835-17 0014 Cardiovascular disease • Dietary
induction of severe atherosclerosis and its prevention
(dogs)
POlHL-06835-17 0015 Cardiovascular disease • Plasma
cholesterol esterification in canine atherosclerosis
POlHL-06835-17 0016 Cardiovascular disease - Metabolic
interactions to polyunsaturated fatty acids in atherogenic
diet (dogs)
P01HL06835-17 0017 Cardiovascular disease ■ Studies
on obese hypertensive rats
POlHL-06835-17 0020 Cardiovascular disease - Lipid
metabolism (rats)
POlHL-06835-17 0021 Cardiovascular disease - Animal
study in atherosclerosis (dog, guinea pig)
POlHL-06835-17 0024 Cardiovascular disease - Studies
on the obese spontaneously hypertensive rat
ROlHL-12766-09 Structure-function relation of blood
vessels (rats, monkeys)
R01HL1372208 Acid and alkaline lipases in aortas (rats.
rabbits, human)
P50HL14164-07 0027 A/S SCOR-Comparative and
experimental atherosclerosis Hyper- and
hyporesponsiveness to dietary cholesterol (squirrel monkey)
P50HL14164-07 0028 A/S SCOR-Comparative and
experimental atherosclerosis • Hyper- and
hyporesponsiveness to dietary cholesterol (African green
monkey)
P50HL-14164-07 0029 A/S SCOR-Comparative and
experimental atherosclerosis - Development of pigeon
substrains
P50HL14164-07 0030 A/S SCOR-Comparative and
experimental atherosclerosis - Morphology, angiochemistry-
Diet induced lesions in African green monkey
P50HL14 164-07 0033 A/S SCOR-Comparative and
experimental atherosclerosis - Comparative studies of
lipoprotein distribution and metabolism (monkeys)
P50HL-14164-07 0038 A/S SCOR-Comparative and
experimental atherosclerosis - Peripheral vascular studies-
Cholesterol, lesion regression, vascular function
P50HL-1416407 0042 A/S SCOR-Comparative and
experimental atherosclerosis - Comparative cardiology
laboratory (monkeys)
Study of lipoproteins, artery wall.
Reversal of atherosclerosis in
P50HL-1506207 0018
and atherosclerosis
monkeys
P50HL-15062-07 0021
and atherosclerosis
P50HL-15103-07 0013
Study of lipoproteins, artery wall.
Core laboratories
A/S SCOR-Early natural history of
arteriosclerosis - Experimental models of atherosclerosis
(monkeys)
ROIHL 15174-06 CV disease epidemiology-Second
generation studies (human)
ROlHL-15448-06 Surgical and metabolic aspects of
venous grafts, (dogs, monkeys, rabbits)
ROlHL-16588-05 Collagen synthesis in atherosclerosis
(dogs, rats, rabbits, human)
P50HL-1 7648-04 0021 Study of ischemic heart disease -
Biventricular contractile responses to acute myocardial
infarction (mammals)
ROlHL-18060-04 Exercise and coronary atherosclerotic
heart disease (monkeys)
P50HL-183I8-03 0002 Pathogenesis and complications of
hypertension - Core experimental animal facility (rats,
rabbits)
POlHL-18574-03 0004 Lipoprotein methodology and
biomedical applications - Fine structure and metabolism of
lipoproteins-EM studies (guinea pigs)
POlHL-18645-03 0001 Biology of the artery wall and
atherosclerosis - Primate arterial smooth muscle and
atherosclerosis
POlHL-18645-03 0006 Biology of the artery wall and
atherosclerosis - The platelet and atherosclerosis (monkeys,
baboons)
P50HL-18828-03 0006 Specialized center of research in
thrombosis - Etiology and pathogenesis of atherosclerosis
(rabbit, monkey, rat, human)
P50HL-19362-02 A/S SCOR -Atherosclerosis in nonhuman
primates
P50HL-19362-02 0001 A/S SCOR-Atherosclerosis in
nonhuman primates - Effects of infant nutrition on
atherosclerosis (baboons)
P50HL-19362-02 0002 A/S SCOR-Atherosclerosis in
nonhuman primates - Infant caloric intake, adipose tissue
development and atherosclerosis (baboon)
P50HL-19362-02 0003 A/S SCOR-Atherosclerosis in
nonhuman primates - Heritability of characters related to
atherosclerosis (baboons)
P50HL-19362-02 0004 A/S SCOR-Atherosclerosis in
nonhuman primates - Selective breeding for characters
related to atherosclerosis (baboons)
P50HL19362-02 0016 A/S SCOR-Atherosclerosis in
nonhuman primates - Core laboratory -Animal services
(baboon)
ROlHL-19974-02 Psychologic-behavioral influences on
heart pathology (rats)
POlHL-20993-02 0006 Population dynamics of arterial
cells in atherogenesis - Mechanism of regression of
atherosclerosis by diet and injury (swine)
Effects of metabolic surgery on
Cholesterol cord blood and family
386
NUTRITION, DIET SCHEDULE AND ROUTE
SEE ALSO DRUGS, PHARMACOLOGY, BIOAVAILABILITY
P50HL-14164-07 0030 A/S SCOR-Comparative and
experimental atherosclerosis - Morphology, angiochemistiy-
Diet induced lesions in African green monkey
NUTRITION, DIET SCHEDULE AND ROUTE,
PARENTERAL FEEDING
POIHL 090 11-15 0020 A research and resource program
in blood - Passive immunization in the prevention of
transmission of hepatitis B (human)
** P50HL-1421407 0031 Newborn lung center for hyaline
membrane disease - Essential fatty acid deficiency and
HMD (human)
** P50HL-14218-07 0004 Pulmonary SCOR -Newborn lung
center - Metabolism of infants with respiratory distress
syndrome (human)
ROlHL-15607-06 Physiological control of splanchnic
circulation (dogs)
NUTRITION, DIET THERAPEUTIC
SEE ALSO NUTRITION, DIET SCHEDULE AND ROUTE
SEE ALSO NUTRITIONAL DISORDERS CHEMOTHERAPY
SEE ALSO NUTRITIONAL REQUIREMENTS, DIETARY
SUPPLEMENTS
ROlHL-00487-29 Vasomotor tone and venous return
(human, dogs, monkeys )
ROlHL-01803-23 0005 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Immunologic and dietary synergy in the
pathogenesis of atherosclerosis (rabbits)
ROlHL-06222-18 Clinical and laboratory studies In lipid
metabolism (human, mammals, non-human)
POlHL-06835-17 0014 Cardiovascular disease - Dietary
induction of severe atherosclerosis and its prevention
(dogs)
POlHL-06835-17 0021 Cardiovascular disease - Animal
study in atherosclerosis (dog, guinea pig)
POlHL-06835-17 0024 Cardiovascular disease - Studies
on the obese spontaneously hypertensive rat
ROlHL-1190112 0006 Effects of metabolic surgery on
the hyperlipidemias Drug therapy with ileal bypass
(rabbits)
ROlHL-11901-12 0009
the hyperlipidemias
management program
ROlHL-1 1901-12 0013 Effects of metabolic surgery on
the hyperlipidemias - Human cholesterol and bile acids
dynamics'-lleal bypass
ROlHL-11901-12 0018 Effects of metabolic surgery on
the hyperlipidemias - Jejunoileal bypass-Postoperative
complications (human)
ROlHL-13595-08 Renin and vascular hyper-reactivity in
hypertension (human, rats)
** ROlHL-13654-08 Antilipemic regimes in peripheral
arteriosclerosis (human)
P50HL-14164-07 0032 A/S SCOR-Comparative and
experimental atherosclerosis - Plasma cholesterol, lesion
regression and vascular function (Rhesus monkey)
** P50HL-14197-07 0006 Support for center of research on
arteriosclerosis - Diets and drugs affecting lipid
metabolism (human)
P50HL-I4230-07 0088 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Coronary risk factors in school children-
The Muscatine study
P50HL-14236-05 0005 Prevention of premature
arteriosclerosis - Genetically hyperlipidemic and
hypolipidemic rats
P50HL-14236-05 0010 Prevention of premature
arteriosclerosis - Computer programs
** P50HL-14236-05 0011 Prevention of premature
arteriosclerosis - Nutritional program
" P50HL-14237-07 0006 Support for arteriosclerosis center
- Drug treatment of familial hyperbetalipoproteinemia
(human)
P50HL-15062-07 0018 Study of lipoproteins, artery wall,
and atherosclerosis - Reversal of atherosclerosis in
monkeys
POlHL-15265-05 0014 Program on surgical control of the
hyperlipidemias - Arkansas clinical center
** ROlHL-15504-05 Animal model for studies on averting
atherosclerosis (swine)
ROlHL-155 12-06 Drug treatment of stenosing primate
atherosclerosis (rabbits, monkeys)
** P60HL-17269-04 0043 National heart and blood vessel
research and demonstration center - Dietary modification-
Effect on cardiovascular risk parameters (human)
ROlHL-18454-03 Maximal exercise testing in
hyperlipidemic children
POlHL-18574-03 0006 Lipoprotein methodology and
biomedical applications Lipoprotein transformation,
lipolytic enzymes, diet and lipid lowering agents
R01HL-I9109-03 Regression of chronic atherosclerosis
(rabbits)
ROlHL-19633-02 Pathogenesis and pharmacology of lung
fibrosis (rats, rabbits)
R01HL-19877-02 Prevention of high blood pressure in
children
ROlHL-20369-03 The effect of alcohol on the heart (rats)
** ROlHL-20910-02 The alternative diet for coronary disease
prevention (human)
ROlHL-2092402 Atherosclerosis and arterial cell functions
(human, rabbits)
NUT
POlHL-20993-02 0004 Population dynamics of arterial
cells in atherogenesis - Modifications of cholesterol balance
related to arterial cell divisions (swine)
P50HL-2100602 0001 Specialized center of research in
arteriosclerosis - Clinic and core program
P50HL-2 1006-02 0002 Specialized center of research in
arteriosclerosis - Turnover and metabolism of cholesterol in
man
ROlHL-2142702 Behavioral changes in post infarction
patients
ROlHL-22123-02 The role of the red cell in diabetic
atherosclerosis (human)
ROlHL-22341-01 Pathogenesis of atherosclerosis in rats
R23HL-22345-02 0001 Behavioral cardiovascular
compliance strategies - Long term modification of dietary
patterns (human)
Test for adherence to diets rich in
Lipid research clinic
Establishment of a lipid research clinic
Lipid research clinic
Establishment of a lipid research clinic
Lipid research clinic
Establishment of a lipid research clinic
Lipid research clinic (human)
Prevention of coronary heart disease
** ROlHL-22847-01
linoleic acid
NOlHV-12156-10
NOlHV-12158-10
NOlHV-12159-09
NOlHV-12160-15
NOlHV-22913-09
NOlHV-22914-08
NOlHV-22917-11
NOlHV-22971-07
(human)
NOlHV-22976-07 Multiple risk factor intervention trial.
prevention of coronary heart disease
NOlHV-22977-08 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22979-07 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22980-06 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22981-10 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22982-07 Intervention trial for prevention of
coronary heart disease (human)
NOlHV-22983-07 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-32931-09 Establishment of a lipid research clinic
center
NOlHV-33101-06 Development and conduct of a multiple
risk factor intervention trial (human)
NO lHV-33 105-09 Intervention trial for prevention of
coronary heart disease (human)
NOlHV-33106-06 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-33108-04 Prevention of coronary heart disease
(human)
NOlHV-33109-04 Intervention trial for the prevention of
coronary heart disease (human)
NO lHV-33 110-04 Prevention of coronary heart disease
(human)
NOlHV-42929-08 Risk factor intervention trial for the
prevention of CHD (human)
NOlHV-42930-09 Risk factor intervention trial for the
prevention of CHD (human)
NOlHV-42931-07 Risk factor intervention trail for the
prevention of CHD (men)
NOlHV-4293205 Risk factor intervention trial for the
prevention of CHD (human)
NOlHV-42933-09 Multiple risk factors in coronary heart
disease (human)
** NOlHV-72983-00 Nutrition counseling in hyperlipidemia
NUTRITION, DIET THERAPEUTIC,
HYPERALIMENTATION (THERAPY)
SEE ALSO NUTRITION, DIET SCHEDULE AND ROUTE,
PARENTERAL FEEDING
** POlHL-06835-17 0064 Cardiovascular disease - Studies
in atherosclerosis (human, animals)
NUTRITION, DIET THERAPEUTIC, REDUCING DIET
*• P50HL-14138-05 0010 Center for research on
atherosclerosis - Diet and exercise as therapy in men with
premature atherosclerosis
P50HL-14197-07 0006 Support for center of research on
arteriosclerosis - Diets and drugs affecting lipid
metabolism (human)
ROlHL-19877-02
children
ROlHL-20397-03
(human, rat)
Prevention of high blood pressure in
VLDL-TG metabolism in diabetes mellitis
•Excludes routine methodology OR covers only general protects which preclude Indexing
"Oriented significantly to above subject.
at the specific level.
NUTRITION, DIET THERAPEUTIC, SALT
RESTRICTED
SEE ALSO NUTRITION, DIETARY CONSTITUENTS, DIETARY
SALTS
*' POlHL-06835-17 0046 Cardiovascular disease - Renin
activity during salt depletion in essential hypertension
(human)
POlHL-06835-17 0050 Cardiovascular disease - 18-
Hydroxylase block in the 17 alpha-hydroxylase deficiency
syndrome (human)
POlHL-06835-17 0059 Cardiovascular disease -
Metyrapone-induced hypertension in dog
ROlHL-14133-08 Intrarenal regulation of sodium
reabsorption (dogs, hamsters, rats)
P50HL-18323-04 0043 SCOR hypertension center -
Pharmacology-Renin-aldosterone mechanisms in essential
hypertension (human)
(contd)
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
NUT
P01Hl'18S7&'03 0002 Machanisms ol vascular changes
In hypaitanslon Cndocfints. electiolytos. and
hemodynamics In hypertension (pigs)
ROIHI 18891 02 Electrolyte intake and blood pressure in
hypertension (human)
ROIHI 19467 03 Retulatlon ot blood pressure (rats, do|s)
ROIHI 1987702 Prevention ol hijh blood pressure in
children
ROIHI 2027802
(rats)
ROIHI 2091002
Cellular mechanisms ol renin secretion
The alternative diet tor coronary disease
prevention (human)
NUTRITION, DIET THERAPEUTIC, VITAMIN
THERAPY (All ROUTES OF ADMINISTRATION)
** P60HL 23282 01 0003 Comprehensive hospital/community
sickle cell center Treatment ol sickle cell ulcers with
physical therapy and vitamin E (human)
NUTRITION, DIETARY CONSTITUENTS (GENERAL)
SEE ALSO GASTROINTESTINAL FUNCTION, ABSORPTION-
TRANSPORT, DIETARY NUTRIENTS
** R01HL03299-21 Dietary effects on cholesterol metabolism
(rats, rabbits)
ROIHL 11614 11 Trace elements in nutrition (chickens,
rats, human)
P50HL1421407 0028 Nevuborn lung center tor hyaline
membrane disease Relationship ot trace metals to
respiratory failure (dog, sheep, human)
** POlHL-1438807 0159 Regulation of the circulation in
pathological states Early drug and diet interventions and
blood pressure development (rats)
P01HL14388-07 0190 Regulation of the circulation in
pathological states Mechanisms of the tenal actions of
aldosterone (rats)
POlHL-14388-07 0210
pathological states
Regulation of the circulation in
Kallikrein-kinin system in hypertension
Regulation of the circulation in
Effects of dietary sodium on blood
pressure and vascular reactivity
P01HL1438807 0223 Regulation of the circulation in
pathological states - Kallikrein-kinin system in hypertension
(rats)
P01HL14388-07 0224
pathological states
(human)
POlHL-18575-03 0002 Mechanisms of vascular changes
in hypertension - Endocrines, electrolytes, and
hemodynamics in hypertension (pigs)
P50HL-19362-02 0001 A/S SCOR -Atherosclerosis in
nonhuman primates - Effects of infant nutrition on
atherosclerosis (baboons)
ROlHL-21764-01 Ultramicroanalysis of prostaglandins and
related compounds (rats)
ROlHL-22273-01 Oral and lung absorption of nitroglycerin
(rats)
NUTRITION, DIETARY CONSTITUENTS, CAIORIC
CONTENT
SEE ALSO NUTRITION, DIET THERAPEUTIC, REDUCING DIET
P50HL-142 18-07 0004 Pulmonary SCOR-Newborn lung
center ■ Metabolism of infants with respiratory distress
syndrome (human)
** P50HL-19362-02 0002 A/S SCOR -Atherosclerosis in
nonhuman primates - Infant caloric intake, adipose tissue
development and atherosclerosis (baboon)
ROlHL-22567-01 Validation of a cholesterol absorption
method in man
R01HL-22607-01 Role of apolipoprotein E in lipoprotein
metabolism (human)
NOlHV-6295504 Data collection in clinical pathology and
morbid anatomy (men)
NUTRITION, DIETARY CONSTITUENTS, DIETARY
AMINO ACIDS
P50HL-14218-07 0004 Pulmonary SCOR-Newborn lung
center - Metabolism of infants with respiratory distress
syndrome (human)
NUTRITION, DIETARY CONSTITUENTS, DIETARY
CARBOHYDRATES
ROlHL-03299-21 Dietary effects on cholesterol metabolism
(rats, rabbits)
ROlHL-05209-18 Lipid metabolism (monkeys)
ROlHL-06221-17 Composition and structure of plasma
lipoproteins (human, turkeys, baboons)
ROlHL-08506-15 Lipemiacarbohydrate and glyceridc
metabolism (human, rats)
R01HL-1O933-13 Fat metabolism and atherosclerosis
(rabbits, cattle, human, rats)
ROlHL-12138-08 Nutritional regulation of enzyme activity
(rats, human)
ROlHL-12399-13 Specific fatty acids and cholesterol
metabolism (gerbils, rats)
P50HL-14218-07 0004 Pulmonary SCOR-Newborn lung
center - Metabolism of infants with respiratory distress
syndrome (human)
P50HL-15103-07 0013 A/S SCOR -Early natural history of
arteriosclerosis - Experimental models of atherosclerosis
(monkeys)
R01HL15263-06 Lecithin-Cholesterol acetyltransferase
(human, rabbits)
** ROIHL- 15840-02 Sugar-induced heart lesions and vitamin
K deficiency (birds, mammals subhuman)
387
ROlHL-1893803 Pulmonary latty acid ind photpholipid
metabolism (rats)
ROIHI 20910 02 The alternative diet lor coronary distlte
prevention (human)
ROIHL 2260/01 Role of apolipoprotein E in lipoprotein
metabolism (human)
ROIHL 2281201 Regulation ol hepatic production of HOL
(rats)
ROIHL 2315901 Regulation ol lipogenesis by
polyunsaturated fats (rats, chicks)
NUTRITION, DIETARY CONSTITUENTS, DIETARY
IRON
ROIHL 18712 03 Iron deficiency-hyperlipidemia in
development (rats)
NUTRITION, DIETARY CONSTITUENTS, DIETARY
IIPIDS
NOIHI 32926 10 Analysis of lipoproteins (animals)
*• ROlHL-01803 23 0005 Arteriosclerosis, glomerulonephritis,
rheumatic fever Immunologic and dietary synergy in the
pathogenesis of atherosclerosis (rabbits)
ROIHL 01803 23 0015 Arteriosclerosis, glomerulonephritis.
rheumatic fever Immunologic endothelial injury and lipid
diet atherosclerosis (rabbits, monkey)
*• ROIHL 01979 22 Arteriosclerosis in zoo animals on
controlled diets (animals)
ROIHL 03299-21
(rats, rabbits)
NUI
Study ol lipoproteins, artery wall.
Reversal ol atherosclerosis in
Dietary effects on cholesterol metabolism
Epidemiology of atherosclerosis in Evans
Lipid metabolism (monkeys)
Cholesterol biosynthesis and its control
ROlHL-03341-22
Co Georgia
ROlHL-05209 18
ROlHL-05360 19
in liver (rats)
ROIHL 05222 18 Clinical and laboratory studies in lipid
metabolism (human, mammals, nonhuman)
P01HL0683517 0024 Cardiovascular disease Studies
on the obese spontaneously hypertensive rat
POIHL 082 14-15 0005 Chemical and biological properties
of lipids - Metabolism of lipids in animals
R01HL08506-15 Lipemiacarbohydrate and glyceride
metabolism (human, rats)
ROlHL-08634-15 Enzymic cholesterol synthesis (human,
rats, protozoa, yeast)
P01HL08974-14 Natural and experimental atherosclerosis
POlHL-08974 14 0005 Natural and experimental
atherosclerosis • Atherosclerosis, coronary heart disease
and sudden death (human)
POlHL-08974-14 0024 Natural and experimental
atherosclerosis - Atherosclerosis, sterol and lipoprotein
metabolism in nonhuman primates
ROlHL-096 10-14 Control of cholesterol metabolism -Bile
acid transport
ROlHL-09744-14 Experimental vascular sclerosis
(monkeys, rabbits)
ROlHL-1089412 Intestinal bacteria and steroid
metabolism (human, guinea pigs, rabbits, rats)
ROlHL-10933-13 Fat metabolism and atherosclerosis
(rabbits, cattle, human, rats)
ROlHL-12138-08 Nutritional regulation of enzyme activity
(rats, human)
ROlHL-12399-13 Specific fatty acids and cholesterol
metabolism (gerbils, rats)
ROlHL-12766-09 Structure-function relation of blood
vessels (rats, monkeys)
ROlHL-12869-09 Arterial metabolism, diabetes and
atherogenesis (rats, rabbits)
ROlHL-13722-08 Acid and alkaline lipases in aortas (rats,
rabbits, human)
P50HL-14164-07 0027 A/S SCOR -Comparative and
experimental atherosclerosis - Hyper- and
hyporesponsiveness to dietary cholesterol (squirrel monkey)
P50HL-14164-07 0028 A/S SCOR-Comparativc and
experimental atherosclerosis - Hyper- and
hyporesponsiveness to dietary cholesterol (African green
monkey)
P50HL-14 164-07 0033 A/S SCOR -Comparative and
experimental atherosclerosis - Comparative studies of
lipoprotein distribution and metabolism (monkeys)
P50HL-14164-07 0036 A/S SCOR -Comparative and
experimental atherosclerosis - Connective tissue
metabolism-Interaction with arterial metabolism (monkeys)
P50HL-14164-07 0037 A/S SCOR-Comparative and
experimental atherosclerosis - Genetic control of plasma
cholesterol -Interaction of dietary fatty acid (monkey)
P50HL 14164-07 0042 A/S SCOR-Comparative and
experimental atherosclerosis - Comparative cardiology
laboratory (monkeys)
P50HL-141 97-07 0006 Support for center of research on
arteriosclerosis - Diets and drugs affecting lipid
metabolism (human)
P50HL-14230-07 0093 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Clinical studies involving cellular lipid
content (human)
P50HL-1423707 0005 Support for arteriosclerosis center
- Genetic determinants of apolipoprotein variability in
lipoproteins (human)
ROlHL-14378-07 Lipemias and reconstructive cardiac
surgery (human)
ROlHL-14781-08 Lipid deposition in mammalian cells
(mice)
P50HI 15062 07 0018
and atherosclerosis
monkeys
P50H1 15103 0/ 0013 A/S SCOR Early natural hulory ol
arteriosclerosis Experimental models of atherosclaroiit
(monkeys)
ROIHI 1526306 Lecithin Cholesterol acetyltransteraM
(human, rabbits)
ROIHL 152/3 06 Metabolism ol pulmonary surfactant
(human, rats)
ROIHt 15478 05 Lipid llux and collagen synthesis in
atherosclerosis (rabbits)
ROIHI 15504 05 Animal model lor studies on averting
atherosclerosis (swine)
ROIHL 1551206 Drug treatment ol slenosing primate
atherosclerosis (rabbits, monkeys)
POIHL 15596 05 0018 Coagulation, librinolysii,
hemostasis and hepatitis Increased plasma lipids on
blood coagulation and thrombosis (human, animals)
ROIHL 15797 05 Lipid metabolism and atherosclerosis m
primates (monkeys, human, squirrels)
ROIHL 15813 05 Cardiac anoxia Protective effect ol
carbohydrate (dogs)
ROIHL 16206 04 Regression of atherosclerotic plaques
(monkeys, dogs)
ROIHL 16587 04 Cholesterol binding saponins and
atherosclerosis (monkeys)
ROIHL 1658805 Collagen synthesis in atherosclerosis
(dogs, rats, rabbits, human)
ROIHL 17332-04 Use of the gut for therapy of coronary
artery disease (mammals)
ROIHL 17516-04 Role ol androgen as a risk factor in
atherogenesis (human, animals)
ROIHL 17564-03 Unsaturated lats-Modc of
hypocholesterolemic action (minipig)
ROlHL-17747-04 Endothelial in|ury and regeneration (rats)
ROlHL-17818-05 Metabolism of cholesterol and cholesterol
in man (also rats, monkeys)
ROIHL- 18060-04 Exercise and coronary atherosclerotic
heart disease (monkeys)
ROlHL-18219-04 Regulation of cholesterol metabolism
(rats)
* ROlHL-18239-03 Dietary fat composition and
prostaglandin synthesis (rats)
ROIHL 18610-03 Early intervention of age related arterial
changes (pigeon)
ROlHL-18623-12 Physical chemistry of biologically active
lipids (bacteria, plant, cattle, human)
ROlHL-18636-02 Fatty acids and cholesterol transport
(rats)
POlHL-18645-03 0005 Biology of the artery wall and
atherosclerosis - Effects of atherosclerosis risk factors on
endothelium of the primate
POlHL-18645-03 0007 Biology of the artery wall and
atherosclerosis - Lipoprotein metabolism in subhuman
primates
ROlHL-18682-03 Protein kinase and cholesterol
metabolism in aorta (rabbits)
P50HL-18828-03 0006 Specialized center of research in
thrombosis - Etiology and pathogenesis of atherosclerosis
(rabbit, monkey, rat, human)
R01HL18938-03 Pulmonary fatty acid and phospholipid
metabolism (rats)
'• ROlHL-19109-03
(rabbits)
Regression of chronic atherosclerosis
Biosynthesis of plasma lipoprotein (rats.
ROlHL-19168-03
rabbits)
ROlHL-19223-03 Control of cholesterogenesis in leukocytes
and liver (rats, human)
POlHL-19242-02 0002 Study of vascular smooth muscle -
Vascular smooth muscle response to serum lipoproteins
(rats)
P50HL-19362-02 A/S SCOR -Atherosclerosis in nonhuman
primates
P50HL- 19362-02 0001 A/S SCOR -Atherosclerosis in
nonhuman primates - Effects ol infant nutrition on
atherosclerosis (baboons)
P50HL-19362-02 0002 A/S SCOR-Athcrosclerosis in
nonhuman primates - Infant caloric intake, adipose tissue
development and atherosclerosis (baboon)
P50HL-19362-02 0003 A/S SCOR -Atherosclerosis in
nonhuman primates - Heritability of characters related to
atherosclerosis (baboons)
P50HL-19362-02 0004 A/S SCOR-Atherosclerosis in
nonhuman primates - Selective breeding for characters
related to atherosclerosis (baboons)
P50HL-19362-02 0005 A/S SCOR-Atherosclerosis in
nonhuman primates - Hybridization to produce primate
model of atherosclerosis (baboon. Rhesus)
P50HL-19362-02 0009 A/S SCOR-Atherosclerosis m
nonhuman primates - Cholesterol metabolism and
intestinal microflora (baboon)
P50HL-19362-02 0013 A/S SCOR-Atherosclerosis in
nonhuman primates • Core laboratory-Lipid biochemistry
(baboons)
P50HL-19362-02 0016
nonhuman primates
(baboon)
R01HL19936-02
the aorta (rats)
ROlHL-20397-03
(human, rat)
A/S SCOR-Atherosclerosis in
Core laboratory -Animal services
Unsaturated fatty acid biosynthesis in
VLDL-TG metabolism in diabetes mellitis
(contd)
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
••Oriented significantly to above subject.
M Grant has subpraiects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
NUT
ROlHL-20910-02 The alternative diet for coronary disease
prevention (human)
ROlHL-21416-02 Atherosclerosis in new modles of
diabetes mellitus
ROlHL-21460-02 Lipoproteins, hemostasis and
atherosclerosis (human, rabbits)
** ROlHL-21513-02 Metabolism of trans fatty acids (human,
rats, swine)
ROlHL-2159201 Lipoproteins and coagulation factors in
atherosclerosis (pigeons)
ROlHL-22123-02 The role of the red cell In diabetic
atherosclerosis (human)
ROlHL-22567-01 Validation of a cholesterol absorption
method in man
ROlHL-22607-01 Role of apolipoprotein E in lipoprotein
metabolism (human)
ROlHL-22847-01 Test for adherence to diets rich In
linoleic acid
ROlHL-22967-01 Structure and function of heparin
rcleasable lipases (swine, human)
** ROlHL-23159-01 Regulation of lipogenesis by
polyunsaturated fats (rats, chicks)
** ROlHL-2359801 Dietary fat, cholesterol and bile acid
turnover (rats)
NUTRITION, DIETARY CONSTITUENTS, DIETARY
LIPIDS, ESSENTIAL FATTY ACIDS
ROIHL-05062-18 Lipid metabolism in cultured cells
(human, rats, rabbits)
POlHL-06835-17 0016 Cardiovascular disease ■ Metabolic
interactions to polyunsaturated fatty acids in atherogenic
diet (dogs)
" POlHL-06835-17 0063 Cardiovascular disease - Studies
on prostaglandins (human, rabbits)
POlHL-08214-15 0005 Chemical and biological properties
of lipids - Metabolism of lipids in animals
** P50HL-14214-07 0031 Newborn lung center for hyaline
membrane disease • Essential fatty acid deficiency and
HMD (human)
P50HL14218-07 0004 Pulmonary SCOR-Newborn lung
center - Metabolism of infants with respiratory distress
syndrome (human)
ROlHL-15273-06 Metabolism of pulmonary surfactant
(human, rats)
ROlHL-204 11-03 Platelet fatty acid metabolism in
diabetes (rat, rabbit, guinea pig)
NUTRITION, DIETARY CONSTITUENTS, DIETARY
PROTEINS
SEE ALSO PUNTS PROTEINS
R01HL03299-21 Dietary effects on cholesterol metabolism
(rats, rabbits)
ROlHL-05209-18 Lipid metabolism (monkeys)
ROlHL-12399-13 Specific fatty acids and cholesterol
metabolism (gerbils, rats)
** R01HL-22617-01 Angiotensin, hypertension and the CNS
(sheep)
NUTRITION, DIETARY CONSTITUENTS, DIETARY
RESIDUES-FIBERS
ROlHL-02033-23 Regulation of cholesterol esters in blood
and tissues (rat, cattle, human)
ROlHL-03299-21 Dietary effects on cholesterol metabolism
(rats, rabbits)
ROlHL-05209-18 Lipid metabolism (monkeys)
** POlHL-06835-17 0064 Cardiovascular disease - Studies
in atherosclerosis (human, animals)
ROlHL-1658704 Cholesterol binding saponins and
atherosclerosis (monkeys)
ROlHL-20910-02 The alternative diet for coronary disease
prevention (human)
POlHL-20993-02 0004 Population dynamics of arterial
cells in atherogenesis - Modifications of cholesterol balance
related to arterial cell divisions (swine)
ROlHL-22567-01 Validation of a cholesterol absorption
method in man
NUTRITION, DIETARY CONSTITUENTS, DIETARY
SALTS
SEE ALSO NUTRIENT INTAKE ACTIVITY, SALT INTAKE
POlHL-06835-17 0060 Cardiovascular disease -
Ventricular performance experimental models of arterial
hypertension (rats, dogs)
** ROlHL-09911-12 Hormonal and dietary modification of
NaCl toxicity (rats) mice)
** P01HL-I4388-07 0210 Regulation of the circulation in
pathological states - Effects of dietary sodium on blood
pressure and vascular reactivity
R01HL14944-07 Renal vascular reactivity in hypertensive
patient
P50HL-15103-07 0013 A/S SCOR -Early natural history of
arteriosclerosis - Experimental models of atherosclerosis
(monkeys)
ROlHL-16658-05
reabsorption
ROlHL-18893-03
receptor (rats)
P50HL-1936202 0012 A/S SCOR-Atherosclerosis in
nonhuman primates - Induction of chronic hypertension by
salt loading (baboon)
R23HL-21066-02 Angiotensin and prostaglandin control of
aldosterone (rats)
388
Prorenin -Physiological and biochemical
Hemodynamic effects of dietary sodium
Iso-renins in the hypertensive rat
Blood volume distribution in hypertension
NUT
Intrarenal regulation of sodium
Mechanism of angiotensin action -Role of
ROlHL-21274-01
analysis (human)
** ROlHL-21523-01
in man
ROlHL-21877-01
ROlHL-21893-01
(human)
ROlHL-22225-01 Hormonal regulation of blood pressure
and blood flow (human, animals)
ROlHL-22306-01 Renal catecholamines- Pathophysiology
of hypertension (dogs)
ROlHL-22506-01 Hemodynamics of the clinical
hypertensions
ROlHL-22603-01 Trace metals, vascular activity and
hypertension (rats)
ROlHL-22977-01 Role of vasoconstrictor mechanisms in
heart failure (human, dogs)
ROlHL-22990-01 Angiotensin II receptors- Mechanisms of
regulation (rats)
ROlHL-23201-01 Mechanisms of hypertension (human
rats)
NUTRITION, DIETARY CONSTITUENTS, DIETARY
TRACE ELEMENTS AND MINERALS
SEE ALSO METALS, HEAVY METALS. CADMIUM
SEE ALSO METALS, HEAVY METALS. CHROMIUM
SEE ALSO METALS, HEAVY METALS. COBALT
SEE ALSO METALS, HEAVY METALS, COPPER
SEE ALSO METALS, HEAVY METALS, MANGANESE
SEE ALSO METALS, HEAVY METALS, ZINC
SEE ALSO METALS, METALLOIDS, SELENIUM
** ROlHL-11614-11 Trace elements in nutrition (chickens,
rats, human)
** P50HL-142 14-07 0028 Newborn lung center for hyaline
membrane disease - Relationship of trace metals to
respiratory failure (dog, sheep, human)
P60HL- 16008-06 0015 Wayne State University
comprehensive sickle cell center - Trace elements in sickle
cell disease (human)
ROlHL-187 12-03 Iron deficiency-hyperlipidemia in
development (rats)
** ROlHL-2244601 Chemical and functional studies of low
copper in lung (pigs)
NUTRITION, DIETETICS
SEE ALSO NUTRITION, DIET SCHEDULE AND ROUTE
SEE ALSO NUTRITIONAL REQUIREMENTS
P60HL-1726904 0043 National heart and blood vessel
research and demonstration center - Dietary modification-
Effect on cardiovascular risk parameters (human)
** ROlHL-20910-02 The alternative diet for coronary disease
prevention (human)
** NOlHV-62941-01 Nutrition coding center for MRFIT and
LRC programs
NUTRITION, JMATERNAL-FETAL NUTRITION
POlHL-0628518 0133 Cardiovascular-respiratory
physiology and biochemistry - Decreased uterine blood flow
and fetal development (lambs)
** ROlHL-187 12-03 Iron deficiency-hyperlipidemia in
development (rats)
NUTRITION, NUTRITION THERAPY (NON-
NUTRITIONAL DISORDERS)
ROIHLI 1901-12 0006 Effects of metabolic surgery on
the hyperlipidemias - Drug therapy with ileal bypass
(rabbits)
P50HL-142 18-07 0004 Pulmonary SCOR-Newborn lung
center - Metabolism of infants with respiratory distress
syndrome (human)
P60HL-1 7269-04 0043 National heart and blood vessel
research and demonstration center - Dietary modification-
Effect on cardiovascular risk parameters (human)
R01HL1845403 Maximal exercise testing in
hyperlipidemic children
ROlHL-18891-02 Electrolyte intake and blood pressure in
hypertension (human)
ROlHL-19877-02 Prevention of high blood pressure in
children
ROlHL-20910-02 The alternative diet for coronary disease
prevention (human)
POlHL-20993-02 0004 Population dynamics of arterial
cells in atherogenesis - Modifications of cholesterol balance
related to arterial cell divisions (swine)
P50HL-21006-02 0001 Specialized center of research in
arteriosclerosis - Clinic and core program
P50HL-21006-02 0002 Specialized center of research in
arteriosclerosis - Turnover and metabolism of cholesterol in
man
R23HL-22345-02 0001 Behavioral cardiovascular
compliance strategies - Long term modification of dietary
patterns (human)
P60HL2328201 0003 Comprehensive hospital/community
sickle cell center - Treatment of sickle cell ulcers with
physical therapy and vitamin E (human)
NUTRITION STUDY SECTION
** R01HL03299-21 Dietary effects on cholesterol metabolism
(rats, rabbits)
** ROlHL-05209-18 Lipid metabolism (monkeys)
** ROlHL-09744-14 Experimental vascular sclerosis
(monkeys, rabbits)
** R01HL1161411 Trace elements in nutrition (chickens,
rats, human)
Nutritional regulation of enzyme activity
ROlHL-12138-08
(rats, human)
R01HL12399-13 Specific fatty acids and cholesterol
metabolism (gerbils, rats)
ROlHL-15478-05 Lipid flux and collagen synthesis in
atherosclerosis (rabbits)
R01HL15504-05 Animal model for studies on averting
atherosclerosis (swine)
ROlHL-15840-02 Sugar-induced heart lesions and vitamin
K deficiency (birds, mammals subhuman)
ROlHL-1756403 Unsaturated fats -Mode of
hypocholesterolemic action (minipig)
ROlHL-18239-03 Dietary fat composition and
prostaglandin synthesis (rats)
R01HL18636-02 Fatty acids and cholesterol transport
(rats)
ROlHL-18712-03 Iron deficiency-hyperlipidemia in
development (rats)
R01HL19399-02 Atherosclerosis -Early events and
regression factors (rats)
R01HL19936-02
the aorta (rats)
ROlHL-21513-02
Unsaturated fatty acid biosynthesis in
Metabolism of trans fatty acids (human.
Test for adherence to diets rich in
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
**Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects
See Appendix for investigator's name and grant number.
rats, swine)
** ROlHL-22847-01
linoleic acid
** ROlHL-23159-01 Regulation of lipogenesis by
polyunsaturated fats (rats, chicks)
** ROlHL-23598-01 Dietary fat, cholesterol and bile acid
turnover (rats)
NUTRITION THERAPY (NON-NUTRITIONAL
DISORDERS)
SEE NUTRITION, NUTRITION THERAPY (NON-NUTRITIONAL
DISORDERS)
NUTRITIONAL ABNORMALITIES
SEE ALSO GASTROINTESTINAL DISORDERS. MALABSORPTION
SYNDROMES
SEE ALSO IRON DISORDERS AND IMBAUNCES
SEE ALSO METAL DISORDERS AND IMBALANCES, MAGNESIUM
DEFICIENCY
ROlHL-0692416 Humoral and metabolic aspects of
cardiac function (mammals, non-human, human)
** P50HL1421407 0028 Newborn lung center for hyaline
membrane disease - Relationship of trace metals to
respiratory failure (dog, sheep, human)
ROlHL-18938-03 Pulmonary fatty acid and phospholipid
metabolism (rats)
NUTRITIONAL ABNORMALITIES,
HYPOVITAMINOSIS A
R01HL1534106 Lung hormonal and chromosomal
regulation (rats, rabbits)
P50HL-21006-02 0003 Specialized center of research in
arteriosclerosis ■ Transport of vitamin A in plasma (human,
rat)
NUTRITIONAL ABNORMALITIES,
HYPOVITAMINOSIS B, CHOLINE DEFICIENCY
ROlHL-12399-13 Specific fatty acids and cholesterol
metabolism (gerbils, rats)
NUTRITIONAL ABNORMALITIES,
HYPOVITAMINOSIS B, THIAMINE DEFICIENCY
ROlHL-0692416 Humoral and metabolic aspects of
cardiac function (mammals, non-human, human)
POlHL-10539-12 0068 Pathophysiology of circulation ■
Acute and chronic cardiomyopathies (mice, dogs, hamsters,
human)
NUTRITIONAL ABNORMALITIES,
HYPOVITAMINOSIS C
SEE ALSO VITAMIN C
POlHL-06835-17 0016 Cardiovascular disease - Metabolic
Interactions to polyunsaturated fatty acids in atherogenic
diet (dogs)
NUTRITIONAL ABNORMALITIES,
HYPOVITAMINOSIS E
POlHL-16833-04 0014 Hemoglobin and red cell system in
hemoglobinopathies - Erythrocyte membrane damage in Hb
SS disease (human)
ROlHL-22951-01 Studies on the affect of vitamin E on
platelets (human, rats)
NUTRITIONAL ABNORMALITIES,
HYPOVITAMINOSIS K
ROlHL-15840-02 Sugar-induced heart lesions and vitamin
K deficiency (birds, mammals subhuman)
ROlHL-21431-02 Factor II antigen and coagulant activity
(human, animals)
NUTRITIONAL ABNORMALITIES, MALNUTRITION
(GENERAL)
SEE ALSO GASTROINTESTINAL DISORDERS. MALABSORPTION
SYNDROMES
POlHL-082 14-15 0006 Chemical and biological properties
of lipids ■ Analysis and properties of lipids
POlHL-10436-13 0008 A multidisciplinary study of
congenital heart disease - Physiologic consequences of
chronic hypoxemia (human)
ROlHL-12399-13 Specific fatty acids and cholesterol
metabolism (gerbils, rats)
(contd)
NUT
ROIHI 1361909 MIcrosomiil elecUon transport in li«e(
and htart (human, mammals)
•• P50HI 14214 07 0031 Newborn lun| center lor hyaline
membrane disease Essential tatty acid deficiency and
HMD (human)
ROIHL 1527306 Metabolism ol pulmonary surlactani
(human, rats)
POIHI 17871 04 0010 Kidney, sodium, cardiac output.
arterioles and hypertension Renal prostaglandins
metabolism in hypertension (rats, dogs)
ROIHL 21912 01 Biosynthesis o( lipoic acid and
atherosclerosis (birds. chicK embryos)
** ROIHL 2244601 Chemical and functional studies ol low
copper in lung (pigs)
NUTRITIONAL ABNORMALITIES, PROTEIN
DEFICIENCY
" POIHL 19717 02 0026 Response of the lung to injury
Protein depletion and postnatal lung development (rats)
NUTRITIONAL ABNORfAALITIES, STARVATION
SEE ALSO NUTRITION. DIET. FASTING
R01HL1213808 Nutritional regulation ol enzyme activity
(rats, human)
POlHL-2098402 0004 Cellular mechanisms in cardiac
hypertrophy Myofibril accumulation in cardiac and
vascular muscle cells in hypertrophy
POlHL-2261901 0007 Cellular mechanisms of heart
failure Regulation of contractile protein levels in heart
muscle (rats)
ROlHL-2265101 Control of protein metabolism in heart
muscle
NUTRITIONAL DISORDERS CHEMOTHERAPY
SEE ALSO NUTRIENT INTAKE ACTIVITY. APPETITE
DEPRESSANTS
SEE ALSO NUTRITION. DIET THERAPEUTIC
SEE ALSO NUTRITION, DIET THERAPEUTIC. VITAMIN THERAPY
(ALL ROUTES OF ADMINISTRATION)
ROlHL-2143102 Factor II antigen and coagulant activity
(human, animals)
NUTRITIONAL REQUIREM!=NTS
SEE ALSO NUTRITION. DIETARY CONSTITUENTS. DIETARY
LIPIDS. ESSENTIAL FAHY ACIDS
ROlHL-12399-13 Specific latty acids and cholesterol
metabolism (gerbils. rats)
** P50HL-14218-07 0004 Pulmonary SCOR -Newborn lung
center - Metabolism of infants with respiratory distress
syndrome (human)
NUTRITIONAL REQUIREMENTS, DIETARY
SUPPLEMENTS
P50HL14214-07 0031 Newborn lung center for hyaline
membrane disease - Essential fatty acid deficiency and
HMD (human)
ROlHL-18891-02 Electrolyte intake and blood pressure in
hypertension (human)
ROlHL-22446-01 Chemical and functional studies of low
copper in lung (pigs)
NYLON
SEE PLASTICS. NYLON
NYSTATIN
SEE ANTIBIOTICS. NYSTATIN
OBESITY
SEE BODY WEIGHT, OBESITY
OBESITY HEREDITARY HYPERGLYCEMIC
SEE METABOLIC DISORDERS INBORN. OBESITY HEREDITARY
HYPERGLYCEMIC
OBESITY REVERSING FACTOR, PITUITARY
SEE LIPID MOBILIZING FACTORS PITUITARY
OBLITERATION VASCULAR, THERAPEUTIC
SEE CARDIOVASCUUR SURGERY, VASCUUR OCCLUSION
THERAPEUTIC
OCCIPITAL LOBE
SEE BRAIN, CEREBRUM, OCCIPITAL LOBE
OCCLUSION VASCULAR, THERAPEUTIC
SEE CARDIOVASCULAR SURGERY. VASCULAR OCCLUSION
THERAPEUTIC
OCCUPATIONAL DISEASES
SEE OCCUPATIONAL HEALTH, OCCUPATIONAL DISEASES
OCCUPATIONAL HAZARDS
SEE OCCUPATIONAL HEALTH, OCCUPATIONAL HAZARDS
OCCUPATIONAL HEALTH
R01HL-18907-03 Objective evaluation early after Ml and
heart surgery (human)
OCCUPATIONAL HEALTH, INDUSTRIAL MEDICINE
** P01HL-10539-12 0066 Pathophysiology of circulation -
Usefulness of relaxation response in industrial settings
** P50HL18323-04 0035 SCOR hypertension center ■ Control
of high blood pressure at the work site
" R25HL18424-03 Blood pressure education in an industrial
setting (human)
389
OCCUPATIONAL HEALTH, OCCUPATIONAL
DISEASES
SH Also METAIS POISONING
SEE ALSO OCCUPAIIONAl HEAIIH, OCCUPATIONAl HAZARDS
SEE ALSO RESPIRATORY OISORDFRS, BYSSINOSIS
SEE ALSO RESPIRATORY DISORDERS, PNEUMOCONIOSIS
SEE ALSO RESPIRATORY DISORDERS. PNEUMONITIS ALLERGIC
INTERSTITIAL, FARMER'S LUNG
ROIHL 12833 09 Genetic and environmental influences on
lung disease (human)
P50HL 1415307 0001 lohns Hopkins Lung Center
Chronic diseases ot airways Genetic and environmental
laclors in chronic pulmonary disease (human)
M P50HL 1509207 Immune and fibrotic response to
occupational environments
*" P50HL 1509207 0001 Immune and fibrotic response to
occupational environments X ray diffraction study Oust
exposure in asbestos cement products manufacturing
** P50HL 1509207 0002 Immune and fibrotic response to
occupational environments Longitudinal sliidv o'
sandblasters silicosis (human)
** P50HL 15092 07 0005 Immune and fibrotic response to
occupational environments Respiratory and immunologic
evaluation ol toluene diisocyanate exposure (human)
" P50HL- 1509207 0006 Immune and fibrotic response to
occupational environments Immunologic studies in
silicosis (human, rabbits, hamsters, guinea pigs)
** P50HL1509207 0007 Immune and fibrotic response to
occupational environments Asbestosis- Cellular immunity,
structure and mineral localization (human)
** P50HL-1509207 0010 Immune and fibrotic response to
occupational environments Characterization of toluene
diisocyanate in industrial environments
** P50HL 15092 07 0011 Immune and fibrotic response to
occupational environments - Respiratory and immunologic
responses in coffee plant workers
** P50HL-15092-07 0012 Immune and fibrotic response to
occupational environments • Longitudinal evaluation of
workers exposed to cotton dust
"* P50HL15092 07 0013 Immune and fibrotic response to
occupational environments - Epidemiology core resource
** P50HL-1509207 0014 Immune and fibrotic response to
occupational environments - Clinical immunology core
resource
P50HL-15389-07 0001 Pulmonary SCOR -Hypersensitivity
pneumonitis - Clinical studies of hypersensitivity
pneumonitis
P50HL-15389-07 0009 Pulmonary SCOR-Hypersensitivity
pneumonitis - Clinical studies -Pulmonary mycotoxicosis
P60HL-17292-04 0003 Vermont Lung Center - Subclinical
pulmonary disease in a rural environment (human)
** P60HL-17292-04 0005 Vermont Lung Center - Mineral
pneumoconioses -Pathogenesis and pathology (human)
ROlHL-17543-03 0001 Magnetic tracers for diagnosis of
lung disease - Chronic, interstitial lung disease (human,
rabbits)
ROlHL-17543-03 0002 Magnetic tracers for diagnosis of
lung disease - Magnetite as an index of asbestos exposure
(human)
ROlHL-17543-03 0003 Magnetic tracers for diagnosis of
lung disease ■ Occupationally accumulated magnetite for
diagnosis of lung disease (human)
ROlHL-19237-03 Obstructive lung disease and alveolar
macrophages (human, animals)
** ROlHL-20815-02 Validation of indirect tests of small
airways function (human, dogs, ponies)
OCCUPATIONAL HEALTH, OCCUPATIONAL
HAZARDS
P50HL-191 70-02 0005 Harvard pulmonary SCOR-Chronic
diseases of the airways - Pulmonary toxicology of plastics
intermediates and pyrolysis products (animal)
** ROlHL-20364-01 Episodic hypertension associated with
human behavior (air traffic controllers)
NOlHR-32903-11 Pilot study to standardize the
measurement of 'closing volume' (human)
OCCUPATIONS
SEE ALSO CHILD WELFARE. CHILD CARE PERSONNEL
SEE ALSO EDUCATION. TEACHING
SEE ALSO HEALTH CARE SERVICES. REHABILITATION
VOCATIONAL
SEE ALSO SOCIOECONOMICS. INCOME, LOW INCOME GROUPS
R01HL-0469717 International heart disease epidemiology
(human)
P50HL-14136-07 0016 Pulmonary SCOR -Airways
obstructive diseases - Environmental factors in airways
obstructive diseases (human)
POlHL-197 17-02 0039 Response of the lung to injury -
Lung scanning in alveolitis and asbestolic interstitial
pneumonia (human, animal)
POlHL-197 17-02 0043 Response of the lung to injury -
Asbestosis as a model of usual interstitial pneumonia
(human)
P01HL197 17-02 0044 Response of the lung to injury ■
Lung sound analysis (human)
** NOlHV-829 13-00 Demonstration programs in hypertension
control in the work setting (human)
OCCUPATIONS, AGRICULTURAL WORKERS
P50HL-1538907 0009 Pulmonary SCOR-Hypersensitivity
pneumonitis - Clinical studies -Pulmonary mycotoxicosis
OLI
OCCUPATIONS, EMPLOYMENT
ROIHI 143/8 0/ liptmiii and reconilfudlv* caidiac
surgery (human)
ROIHI 20364 01 Episodic hypertension aitociilad with
human behavior (air trallic tonlrolleri)
OCCUPATIONS, INDUSTRY
ROIHI 12833 09 Genetic and environmental lnflue^ce^ on
lung disease (human)
M P50HI 15092 07 Immune and fibrotic response to
occupational environments
P50HL 1509207 0001 Immune and fibrotic response to
occupational environments X ray dilfraction study Oust
exposure in asbestos cement products manufacturing
P50HL 15092 07 0002 Immune and fibrotic response to
occupational environments Longitudinal study ol
sandblasters silicosis (human)
P50HL 15092-07 0005 Immune and fibrotic response to
occupational environments Respiratory and immunologic
evaluation of toluene diisocyanate exposure (human)
P50HL15UJ2 0? 0006 Immune and fibrotic response to
occupational environments Immunologic studies in
silicosis (human, rabbits, hamsters, guinea pigs)
P50HL15092 07 0010 Immune and fibrotic response to
occupational environments Characterization of toluene
diisocyanate in industrial environments
P50HL1509207 0011 Immune and fibrotic response to
occupational environments Respiratory and immunologic
responses in coHee plant workers
P50HL 15092-07 0012 Immune and fibrotic response to
occupational environments Longitudinal evaluation of
workers exposed to cotton dust
P50HL-15092 07 0013 Immune and fibrotic response to
occupational environments - Epidemiology core resource
P50HL-1509207 0014 Immune and fibrotic response to
occupational environments - Clinical immunology core
resource
OCCUPATIONS, INDUSTRY, MINING
ROlHL-2280201 A rural mining community hypertension
control project (human)
OCCUPATIONS, JOB SATISFACTION
P01HL10539-12 0066 Pathophysiology of circulation -
Usefulness of relaxation response in industrial settings
ROlHL-23078-01 Psychosocial stress and sudden coronary
death (human)
OCCUPATIONS, LEISURE
ROlHL-20662-02 Physical activity, fitness and
epidemiology of CHD
OCCUPATIONS, RECREATION
P60HL-15158-07 0010 Comprehensive sickle cell center -
Tutorial service for sickle cell anemia patients
OCCUPATIONS, VOCATIONAL GUIDANCE
P60HL-16008-06 0011 Wayne State University
comprehensive sickle cell center ■ Education, screening and
counseling
OCEANIC RESEARCH
SEE WATER ENVIRONMENT. OCEANIC RESEARCH
ODORATISM
SEE TOXICOLOGY. PLANT POISONING. LATHYRISM
ODOR (AS OLFACTORY STIMULI)
SEE SENSORY-PERCEPTUAL PROCESSES. OLFACTORY STIMULI
OINTMENTS
SEE DOSAGE FORMS
OLD AGE
SEE AGE (HUMAN), ADULT. OLD AGE (65 TO 99 YRS)
OLD YELLOW ENZYME
SEE OXIDOREDUCTASES. NADPH DEHYDROGENASE
OLD WORLD MONKEYS
SEE MAMMALS. PRIMATES, MONKEYS AND APES
(ANTHROPOIDS. NON-HUMAN), OLD WORLD MONKEYS
(CATARRHINES)*
OLEFINS
SEE CYCLOOLEFINS -ALSO SEE APPROPRIATE
CARBOPOLYCYCLICS AND
OLEIC ACID
SEE FATTY ACIDS. OLEIC ACID
N-OLEOYLSPHINGOSINE
SEE SPHINGOLIPIDS. CERAMIDE
OLFACTORY PATHWAYS
SEE BRAIN. CEREBRUM. HIPPOCAMPAL FORMATION
SEE BRAIN. LIMBIC SYSTEM
OLFACTORY STIMULI
SEE SENSORY-PERCEPTUAL PROCESSES. OLFACTORY STIMULI
OLIGOMYCIN
SEE ANTIBIOTICS. OLIGOMYCIN
OLIGOPEPTIDES
SEE PEPTIDES. OLIGOPEPTIDES
(contd)
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
ou
OUGOSACCHARIDE INTOLERANCE
SEE METABOLIC DISORDERS INBORN. DISACCHARIDE
(OLIGOSACCHARIDE) INTOLERANCE
OUGOSACCHARIDES
SEE ALSO CARBOHYDRATES STRUCTURE, SUGAR SEQUENCE
SEE ALSO METABOLIC DISORDERS INBORN, DISACCHARIDE
(OLIGOSACCHARIDE) INTOLERANCE
** POlHL-11310-12 0099 Mechanisms of cardiowascular
disease - Carbohydrate chemistry of thy-I and related
synaptosomal proteins
P01HL11310-12 0105 Mechanisms of cardiovascular
disease - Biosynthesis of mammalian glycoproteins
(rabbits)
ROlHL-14271-07 Physico-chemical properties of tracheal
mucus (dogs, frogs)
ROlHL-16166-05 Structure of alpha-1-antitiypsin in
relation to emphysema (human)
ROlHL-1 778304 Complex carbohydrates-Structure,
function, synthesis (swine)
ROlHL-17881-15 Biosynthesis and degradation of blood
group substances (human, animals)
R01HL19011-03 Smooth muscle cell membrane
glycoprotein biosynthesis (cattle)
ROlHL-2054702 Glycoproteins in pulmonary alveolar
proteinosis (human)
R01HL-20868-02 Regulation of glycoprotein biosynthesis in
lung (swine)
ROlHL-2139402
(rabbits)
ROlHL-21615-01
Pulmonary angiotensin-converting enzyme
Structural studies of lung heparinoid
polysaccharides (cattle)
ROlHL-22967-01 Structure and function of heparin
releasable lipases (swine, human)
OUGURIA
SEE KIDNEY DISORDERS, ANURIA, OLIGURIA
OMENTUM
SEE BODY CAVITIES. OMENTUM
ON-UNE COMPUTERS
SEE COMPUTER, ON-LINE COMPUTERS*
ONION AND GARUC
SEE PLANTS. ANGIOSPERMS. ALLIUM*
ONTOGENY
SEE AGE (ANIMAL). IMMATURE
SEE EMBRYOLOGY
SEE GROWTH AND DEVELOPMENT
SEE PREGNANCY, EMBRYO-FETUS
OPERANT CONDITIONING
SEE PSYCHOLOGY. CONDITIONING, OPERANT
OPERATIONS RESEARCH
SEE INFORMATION AND COMMUNICATION, SYSTEMS
ANALYSIS. OPERATIONS RESEARCH
OPHTHAIMIC ARTERY
SEE EYE CIRCUUTION, OPHTHALMIC ARTERY
OPSONINS
SEE IMMUNOLOGY, ANTIBODIES, OPSONINS
OPTICAL DENSITY
SEE PHYSICAL PROPERTIES. DENSITOMETRY*
OPTICAL MASERS
SEE OPTICS, LASERS*
OPTICAL ROTATION*
ROlHL-16474-05 Antibiotic-ion interactions (model
membranes)
OPTICS, BIREFRINGENCE*
P01HL-I6I17-05 0004 Ion movements and membranes in
cardiovascular control - Optical studies of excitation-
contraction coupling (frogs, snakes)
POlHL-18576-03 0002 Thrombosis research program
project - Molecular basis of fibrin formation (human, cattle,
lamprey)
OPTICS, CHROMOPHORE*
R01HL-21483-01 Electronic, thermodynamic and kinetics
of hemoglobin
OPTICS, DICHROISM CIRCULAR*
P01HL-06285-18 0215 Cardiovascular-respiratory
physiology and biochemistry - Conformation of biopolymers
** POlHL-16833-04 0015 Hemoglobin and red cell system in
hemoglobinopathies - Stereochemistry of hemoglobins from
magnetic circular dichroism (human)
POlHL-1 74 19-04 0007 Studies on mechanisms of
hemostasis - Structural analysis of ordered forms of
fibrinogen (human, cattle)
POlHL-22619-01 0011 Cellular mechanisms of heart
failure - Reaction of lipoproteins and apolipoproteins with
lipoprotein lipase (cattle)
OPTICS, DICRHOISM CIRCULAR MAGNETIC*
POlHL-16833-04 0015 Hemoglobin and red cell system in
hemoglobinopathies - Stereochemistry of hemoglobins from
magnetic circular dichroism (human)
390
OPTICS, FIBER OPTICS*
** P01HL-06370-I7 0013 Cardiopulmonary and renal
pathology research center - Morphologic analysis of
vascular prosthesis (human, dogs)
R01HL13885-08 9002 Cystic fibrosis and pulmonary
disease - Computer core facility (human)
** ROlHL-13885-08 9003 Cystic fibrosis and pulmonary
disease - Fiberoptic bronchoscopy core facility (human.
dogs, sheep)
** ROlHL-19993-02 Optical detection of platelet aggregates
(human, baboons)
R01HL-20192-02 Ciliary activity of the lung studied by
laser scattering
OPTICS, FLUOROMETRY*
POlHL-07896-15 0032 Environmental biomedical research
program - Fluorometry study of brain exposed to hyperbaric
oxygen (dogs, cats)
ROlHL-15677-06 Autonomic nervous system function in
bronchial asthma (human, guinea pig. rabbit)
P01HL-18708-03 0010 Oxygen, energy and contractility in
cardiac tissue - Tissue oxygen utilization (rats, dogs)
OPTICS, IMAGE ENHANCEMENT*
SEE ALSO OPTICS. PHOTOGRAPHY, HOLOGRAPHY*
POlHL-16910-05 0001 Regulation of the peripheral
circulation - Quantitative studies of microcirculatory control
(bats)
ROlHL-208 72-02 Multidimensional echo imaging of the
ischemic heart
OPTICS, IMAGE PROCESSING ANALYSIS AND
DISPLAY*
M P01HL04664-18 Cardiovascular and lung dynamics
** POlHL-04664-18 0001 Cardiovascular and lung dynamics
- X-ray projection image videodensitometry (dogs)
POlHL-0466418 0002 Cardiovascular and lung dynamics
- X-ray cross section imaging of organs (dogs)
POlHL-04664-18 0003 Cardiovascular and lung dynamics
- X-ray projection image videometry (human, dogs)
** POlHL-04664-18 0008 Cardiovascular and lung dynamics
- Micrographic video imaging technique
** POlHL-04664-18 0009 Cardiovascular and lung dynamics
- Biological signal and image processing techniques (dogs)
POlHL-06664-17 0041 Cardiopulmonary function in
remediable vascular disease - Core facility for quantitative
microscopy
ROlHL-11 153-12 Quantitation of flow and solute flux in
microvessels (cats, rats)
POlHL-1 1307-12 9001 Biophysical studies in pediatric
cardiology - Core support -computer science
POlHL-11414-11 0024 Thrombosis and atherosclerosis
program - Radiographic demonstration of small coronary
arteries (human, dogs)
ROlHL-127 15-10 Dynamic cardiovascular measurement
using ultrasound
** P50HL-141 36-07 0005 Pulmonary SCOR-Airways
obstructive diseases ■ Radiographic studies of airways
obstructive disease (human)
P50HL-14136-07 9004 Pulmonary SCOR-Airways
obstructive diseases - Radiology core (human)
P50HL-14138-05 0009 Center for research on
atherosclerosis - Core angiographic-diagnostic laboratory
(human, dogs, birds)
** P50HL-141 38-05 0016 Center for research on
atherosclerosis - Computer analysis of angiograms
ROlHL-150 16-07 New concepts in cardiac ultrasound
technology (human)
P60HL-16005-05 0015 Comprehensive sickle cell center -
Molecular basis for the sickling phenomenon
ROlHL-16260-04 Development of clinical cine ultrasound
cardiography
** ROlHL-16487-05 Computer controlled two dimensional
echocardiography
R01HL-I6791-03 Computer linkage for a dual camera
system
P60HL-17269-04 0027 National heart and blood vessel
research and demonstration center - Non-invasive
evaluation of cardiac function-lschemic heart disease
(human, dog)
P60HL-17269-04 0031 National heart and blood vessel
research and demonstration center - Computer-assisted
data acquisition and clinical data processing
P50HL-17648-04 0033 Study of ischemic heart disease •
Data management-Electrocardiographic analysis system
** P50HL-17648-04 0034 Study of ischemic heart disease -
Data management-Hemodynamic data
P50HL-17655-04 0011 Study of ischemic heart disease -
Core facility-Cardiovascular nuclear medicine (human, dog)
P50HL-17669-04 0009 Ischemic heart disease center
(SCOR) - Infarct volume-99Tc stannous pyrophosphate
myocardial scintigrams (dogs, human)
P50HL-17670-O4 0014 Study of ischemic heart disease -
Real time ultrasound imaging in ischemic heart disease
(human, dog)
P50HL-17682-04 0009 Study of ischemic heart disease -
Computer core unit
P50HL- 176 82-04 0011 Study of Ischemic heart disease -
Nuclear medicine core unit (human, dogs, rabbits, mice)
ROlHL-17739-04 Acute myocardial infarct scintigraphy
(human, dogs, rats)
ROlHL-17931-04 Normalized body surface potential maps
(children)
OPT
POlHL.18208-04 0002 Center for the study of blood cell
rheology - Holography of RBC shape (human)
POlHL-18646-03 0008 Studies basic to heart
transplantation - Immunophysiology and early detection of
rejection (dogs)
ROlHL-19768-02 Recording and analysis of low levels
cardiac signals (human, dogs)
R23HL-21253-01 Anatomical models in computer-aided
image analysis
ROlHL-2 1684-02 0004 Radionuclide infarct sizing and
therapy evaluation - Image analysis -Kinetics of infarction.
ventricular function (human, animal)
ROlHL-21751-02 0003 Thallium and antimyosin in
ischemia and infarction - Human studies-Ischemia and
infarction
Microcirculation in patients with diabetes
ROlHL-22118-02
mellitus
R01HL-22604-01
studies (human)
ROlHL-22844-01
•Excludes routine metbodotogy OR covers only general projects which preclude indexing at the specific level
Onented significanthf to above subject.
M Grant has subprojects describing specific research aspects
See Appendix for investigator's name and grant number.
Non-invasive system for arteriosclerosis
Phrenic nerve pacing-Noninvasive
diaphragm analysis (human, dogs)
** ROIHL 22893-01 Evaluating arterial disease by velocity-
wave analysis (dogs, human)
NOlHR-62901-04 Measure pulmonary function in infants
and children (also dogs, rabbits)
NOlHV-52966-01 Development and evaluation of an
ultrasonic imaging system (swine)
** NOIHV-72927-00 Systems for non-invasive detection of
atherosclerotic lesions (human)
" NOlHV-72928-04 Develop high resolution ultrasonic
imaging techniques
NOlHV-72930-02 Atherosclerosis assessment-Angiography
and ultrasound (dogs, human)
OPTICS, IMAGING-VISUALIZATION (GENERAL)*
SEE ALSO CARDIOVASCULAR VISUALIZATION*
SEE ALSO CEREBROVASCULAR VISUALIZATION*
SEE ALSO GASTROINTESTINAL VISUALIZATION*
SEE ALSO HEART VISUALIZATION*
SEE ALSO KIDNEY VISUALIZATION*
SEE ALSO PHYSICAL PROPERTIES. SOUND. ULTRASONIC
SCANNING*
SEE ALSO PHYSICAL PROPERTIES. SOUND.
ULTRASONOGRAPHY
SEE ALSO RADIOGRAPHY*
SEE ALSO RESPIRATORY VISUALIZATION*
** ROlHL-20274-02 Gated imaging with the MGH x-ray
camera
ROlHL-2 1706-02 Nuclear magnetic resonance and
myocardial ischemia (rats)
ROlHL-21707-01 Quantification of infarct size by emission
tomography (human, dogs)
P60HL-23282-01 0001 Comprehensive hospital/community
sickle cell center - Fetoscopy for intrauterine diagnosis of
hemoglobinopathy (human, monkeys)
OPTICS, INTERFEROMETRY*
ROlHL-12528-10 NMR relaxation of liquid crystal systems
POlHL-18208-04 0001 Center for the study of blood cell
rheology - Physiological basis of reversible erythrocyte
shape change (human, firefly)
POlHL-18208-04.0002 Center for the study of blood cell
rheology - Holography of RBC shape (human)
OPTICS, LASERS*
SEE ALSO CHEMISTRY, ANALYTICAL MaHODS.
SPECTROMETRY. USER*
SEE ALSO OPTICS, PHOTOGRAPHY. HOLOGRAPHY*
SEE ALSO OPTICS. PHOTOGRAPHY, HOLOGRAPHY, ACOUSTIC*
** R01HL-15740-06 In vitro studies on heart cell function
(rats)
P01HL16683-04 0003 Function and growth of cardiac
and skeletal muscle - Movements of S-1 moieties in muscle
fibers
P01HL-17421-05 0007 Regulation and exchange in the
microcirculation - Core facilities-Fluorometric measurement
methods for microcirculation
ROlHL-18676-03 Myocardial sarcomere mechanics (rat)
ROlHL-18725-03 Light-scattering studies of the sickling
process (human)
POlHL-20552-02 0003 The development and regression of
cardiac hypertrophy - Muscle mechanics of the
hypertrophied left ventricle (rats)
** POlHL-22163-01 0002 Surface thrombogenesis-
Mechanisms and prevention - Laser-scattering detection of
microemboli in blood flow (baboons)
ROlHL-22223-01 The cardiopulmonary junction (dogs,
models)
OPTICS, LIGHT EMISSION, FLUORESCENCE*
SEE ALSO DYES, FLUORESCENT DYES AND PROBES
SEE ALSO RADIOFLUORESCENT PROBES
ROIHL- 17 702-04 Electro-optical dyes as probes of heart
excitability
** POlHL-20984-02 0002 Cellular mechanisms in cardiac
hypertrophy - Thermodynamic, fluorescence, chemical
modification of hypertrophied heart myosin
OPTICS, LIGHT SCATTERING*
POlHL-17421-05 0007 Regulation and exchange in the
microcirculation - Core facilities-Fluorometric measurement
methods for microcirculation
R01HL-18256-01 Optical properties of platelets and
erythrocytes (rabbits, dogs, human)
(contd)
OfT
POIHl'187O('03 0010 Oiygen. antiiy and contiactility in
cardiac tissu* Tissua oiyien utiliiation (rats, dogs)
R01HL'1872S'03 light scattating studies ol ttie sickling
process (human)
ROIHL 1997301 Non invasive sickled cell monitoi
developnient (human)
ROIHI. 2019202 Ciliary activity ot the lung studied by
lastr scattering
ROIHL 2118202 Active tension and shortening in cardiac
hypertrophy (rabbits)
•* POlHL-2216301 0002 Surface thrombogenesis
Mechanisms and prevention Laser scattering detection o<
mlcroemboli in blood How (baboons)
OPTICS, MICROSCOPY (OENERAl)*
POIHL 17421 05 0006 Regulation and exchange in the
microcirculation Core lacilities Optical instrumentation
tacility
*• P50HL1915502 0008 Pathophysiology ot pulmonary
edema - Core microscopy laboratory
*• PSOHL 1915602 0006 Pulmonary SCOR Chronic diseases
of airvvays Core microscopy laboratory
** P50HL1918502 0012 Pulmonary SCOR Neonatal
respiratory distress syndromes ■ Core microscopy lab
ROlHL-2013203 Histogenesis and biochemistry of
embryonic lung (birds)
•* POIHL 2094802 9002 Molecular basis ot cholesterol
metabolism - Microscopy core laboratory
** POlHL-2099302 0011 Population dynamics ot arterial
cells in atherogenesis Light and electron microscopy
laboratories-Core
OPTICS, MICROSCOPY, ELECTRON*
SEE ALSO OPTICS, MICROSCOPY, IMMUNE ELECTRON*
SEE ALSO TEMPERATURE, FREEZE ETCHING*
ROlHL-01803-23 0005 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Immunologic and dietary synergy in the
pathogenesis of atherosclerosis (rabbits)
ROlHL-01803-23 0010 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Atherosclerosis induction -Graft rejection
and hypercholesterolemia (rabbits)
** POlHL-06285-18 0214 Cardiovascular-respiratory
physiology and biochemistry - Membrane structure and
function-EM of macromolecules
•* POlHL-06664-17 0041 Cardiopulmonary function in
remediable vascular disease • Core facility for quantitative
microscopy
P01HL06835-17 0039 Cardiovascular disease -
Reversibility of vascular changes in renal hypertension
(rats)
ROlHL-07652-14 Destruction ot red blood cells in
hemolytic anemias (human, guinea pigs)
•* POlHL-08682-15 0011 Regulation of the cardiovascular
system ■ Histochemistry and ultrastructure of heart
innervation (dogs, ground squirrels)
** POlHL-08805-15 0042 Regulation of ventilation and
pulmonary circulation - Electron microscope core research
laboratory
ROlHL-09125-14 Ultrastructural cytochemistry (human,
chick)
** POlHL-11414-11 0036 Thrombosis and atherosclerosis
program ■ Electron microscopy core facility
ROlHL-1 1822-10 Biophysical studies of macromolecular
interactions (microorganism, human)
ROIHLI 1901-12 0001 Effects of metabolic surgery on
the hyperlipidemias - Partial ileal bypass (human)
POlHL-12738-10 0081 Physiologic pharmacology and its
clinical applications - Ultrastructural and electrophysiologic
alteration of myocardium (human, dogs)
POlHL-12738-10 0108 Physiologic pharmacology and its
clinical applications - Developmental electrophysiology and
pharmacology (human, animals)
ROlHL-13256-08 Amino acid transport by red cell
membranes (pigeons)
** P50HL- 14 164-07 0043 A/S SCOR-Comparative and
experimental atherosclerosis - Electron microscopy resource
laboratory
** P50HL-14217-08 0050 Specialized center of research in
thrombosis - Electron microscopy section (dogs)
P50HL-14230-07 0096 A/S SCOR -Lipids, atherosclerosis
and thrombosis - Ultrastructural studies of endothelial cells
(human)
P50HL-15062-07 0021 Study of lipoproteins, artery wall,
and atherosclerosis - Core laboratories
ROlHL-15740-06 In vitro studies on heart cell function
(rats)
** POlHL-15835-06 0006 Study of muscles related to heart
disease - Ultrastructural and chemical studies of muscle
(animals)
** POlHL-15835-06 0019 Study of muscles related to heart
disease - Vascular smooth muscle-Electron microscopy,
excitation contraction (animal)
** POlHL-15835-06 0027 Study of muscles related to heart
disease - Core ll-lntermediate voltage EM of muscle
P60HL-16005-05 0015 Comprehensive sickle cell center -
Molecular basis for the sickling phenomenon
** POlHL-16117-05 0001 Ion movements and membranes in
cardiovascular control - Developmental studies of
contractile cell junctions (rats, rabbits, elasmobranch)
ROlHL-16375-04 Investigation of hemoglobin S properties
(human)
391
■ POIHI 1660/05 000/ Calcium ion and control of
cardiovascular function Ulttasliucture and conlormation
in sarcoplasmic reticulum (rabbits)
ROIHL 16710 03 Myocardial subcellular localiiation of
calcium (dogs)
* POIHL 16/69 05 0009 Pathobiologic and host defense
reactions in the lung Electron microscopy and tissue
culture core laboratory
• POIHL 16851 04 0011 Human red cell membrane in
health and disease Ultrastructure laboratory Core facility
• ROIHL 173/6 04 Analysis of Z bands in heart by optical
diffraction (mammals)
POIHL 1/419 04 000/ Studies on mechanisms of
hemostasis Structural analysis ol ordered forms of
fibrinogen (human, cattle)
* POIHL 1781204 0005 Thrombosis and plasma proteins •
In vitro systems of normal platelets, white cells, sera
(human)
'* POIHL 17813-04 0002 Lung disease and the oxygenation
ot blood and tissue Diffuse interstitial lung disease-
Ultrastructural abnormalities (human)
POIHL 1820804 0004 Center for the study of blood cell
rheology Splenic microcirculation (rats, mice)
•• POIHL 18574 03 0004 Lipoprotein methodology and
biomedical applications fine structure and metabolism of
lipoproteins- EM studies (guinea pigs)
ROIHL 18631-03 Ultrastructural correlates of myocardial
ischemia (rats, swine)
** ROlHL-18831-03 Microscopy of spontaneously hypertensive
arterial lesion (rats)
ROIHL 19009-03 Morphometric analysis of the sinoatrial
node (ferret)
P50HL-19171-02 0008 Pulmonary SCOR -Lung injury by
childhood infections - Host-parasite interaction -Electron
microscopy, radioautography, histochemistry
ROlHL-193 16-03 Study of glomerular permeability (fish,
turtle, frog, chordates, Crustacea)
POlHL-197 17-02 0024 Response of the lung to injury -
Formation of lung alveoli (rats)
ROlHL-20063-03 Pathogenesis of pulmonary mycoplasma
infections (guinea pigs, mice)
** POlHL-20592-02 0006 Cell biology of cardiac and
skeletal muscle - Permeability and ultrastructure of cardiac
nexuses (rabbits, cattle, rats)
** POIHL 20993-02 0011 Population dynamics of arterial
cells in atherogenesis - Light and electron microscopy
laboratories -Core
POlHL-20994-02 9002 Dynamics of neutrophil elastase in
the lung - Ultrastructural core
POlHL-21016-02 0001 Sickle cell anemia and other
hemoglobinopathies - Supramolecular models of Hb S-
Mutational and EM approach
** POlHL-210 16-02 0018 Sickle cell anemia and other
hemoglobinopathies Scanning and transmission electron
microscopy
** ROlHL-21038-01 Electrically induced cardiac EM-
histochemical changes (animals)
ROlHL-21670-01 Antiarrhythmic studies on 2-substituted
aminoindenes (dogs)
** ROlHL-23161-01 0004 Biology of myocardial ischemia -
Structure of myofibrils and membranes in early ischemia
(dogs, rabbit, rodents)
ROlHL-24021-02 Erythocyte membrane sulfhydrls and Rh
activity (human)
OPTICS, MICROSCOPY, ELECTRON SCANNING*
ROlHL-09125-14 Ultrastructural cytochemistry (human,
chick)
POIHL-11414-11 0036 Thrombosis and atherosclerosis
program - Electron microscopy core facility
P50HL-142 17-08 0050 Specialized center of research in
thrombosis - Electron microscopy section (dogs)
POlHL-16748-05 0001 Cellular and immunological basis
of pulmonary diseases - Mechanisms of alveolar
macrophage function and dysfunction (human, rabbits)
POlHL-16769-05 0009 Pathobiologic and host defense
reactions in the lung - Electron microscopy and tissue
culture core laboratory
** POlHL-16851-04 0011 Human red cell membrane in
health and disease - Ultrastructure laboratory -Core facility
ROlHL-1879804 0002 Nervous and ionic factors in
sudden cardiac death - Electron microprobe, ultrastructure
analysis of ischemic myocardium (dog, rabbit)
P50HL-19171-02 0009 Pulmonary SCOR-Lung injury by
childhood infections - Host-parasite interaction -Scanning
electron microscopy, freeze-fracture methods
** POlHL-21016-02 0018 Sickle cell anemia and other
hemoglobinopathies - Scanning and transmission electron
microscopy
POlHL-22602-01 9001 Pathophysiology of the
endothelium - Morphology core
OPTICS, MICROSCOPY, FLUORESCENCE*
ROlHL-10980-11 Ultrastructural renal pathology (human,
rats)
OPTICS, MICROSCOPY, IMMUNE ELECTRON*
** POlHL-15851-04 0011 Human red cell membrane in
health and disease - Ultrastructure laboratory -Core facility
OPTICS, MICROSCOPY, ULTRASONIC*
** ROlHL-22233-01 Characterization of bio-materials by
elastic property
OPTICS, PHOTOGRAPHY*
SEF Also EOUCAIION, AUDIOVISUAI AND OIHFR TRAINING
AIDS
SEE ALSO ELECIRICAt MtASURf Ml NIS, POUROCRAPHy
SEE ALSO EVE OISORDLRS DIAGNOSIS, REIINOGRAPHY*
SEE ALSO RADIOGRAPHY"
ROIHL 15958 06 X ray diffraction analysis of thrombin
and neurotoxin
POIHL 1/421 05 0006 Regulation and exchange in the
microcirculation Core facilities Optical instrumentation
facility
OPTICS, PHOTOGRAPHY, CINEMATOGRAPHY*
ROIHL 1997502 Laryngeal biomechanics in pulmonary
therapy (primates)
OPTICS, PHOTOGRAPHY, CINEMICROGRAPHY*
P50HL 14212 0/ 0016 Correlated studies of pulmonary
fibrosis Role of pulmonary alveolar macrophages in
fibrosis (human, rabbit)
OPTICS, PHOTOGRAPHY, HOLOGRAPHY*
** POIHL 1820804 0002 Center for the study of blood cell
rheology Holography of RBC shape (human)
•* POlHL-18208-04 0005 Center for the study of blood cell
rheology RBC deformability and capillary How
interrelations (human, mice)
OPTICS, PHOTOGRAPHY, HOLOGRAPHY,
ACOUSTIC*
SEE ALSO PHYSICAL PROPERTIES, SOUND,
ULTRASONOGRAPHY
ROIHL 12494-10 Continuum mechanics in biophysics
(human, animals)
OPTICS, PHOTOGRAPHY,
STEREOPHOTOGRAPHY*
** ROIHL 15888-05 Comparative stereology of the
myocardium (birds, mammals)
OPTICS, PHOTOMICROGRAPHY*
ROlHL-11152-12 Vascular physiology (human, cats, dogs)
ORAL ADMINISTRATION
SEE DOSAGE AND ROUTE, ROUTE OF ADMINISTRATION
ORAL AIRFLOW MEASUREMENT
SEE RESPIRATORY DISORDERS DIAGNOSIS, RESPIRATORY
AIRFLOW MEASUREMENTS*
ORAL FLORA
SEE MICROBIAL ORAL FLORA
ORAL MICROBES
SEE MICROBIAL ORAL FLORA
ORAL-PHARYNGEAL (REGION)
•* P50HL-14214-07 0027 Newborn lung center for hyaline
membrane disease - Oral-laryngeal chemoreceptors and
respiratory failure in newborns (human, sheep)
ROlHL-16730-03 Physiology of mucociliary transport (rats,
frogs, rabbits)
ORAL-PHARYNGEAL, NASOPHARYNX
** POlHL-10436-13 0016 A multidisciplinary study of
congenital heart disease - Genetic studies of congenital
heart disease (human)
ORAL-PHARYNGEAL, PALATE
ROlHL-21257-02 Breathing in sleep -Airway control and
blood gases (cats)
ORAL-PHARYNGEAL, PHARYNX
SEE ALSO ORAL-PHARYNGEAL, NASOPHARYNX
P50HL-14218-07 0005 Pulmonary SCOR -Newborn lung
center - Prevention of infection in infants with respiratory
distress (human)
ROlHL-21257-02 Breathing in sleep-Airway control and
blood gases (cats)
ORAL-PHARYNGEAL, SALIVA
** ROlHL-14148-07 0007 The regional circulations - Salivary
composition in hypertension (human)
NOlHR-72920-01 Identify and quantity cystic fibrosis
factors (human)
ORAL-PHARYNGEAL, SALIVARY GLANDS
ROlHL-18601-01 Regulation of neurotransmitter release by
adenosine (rats)
ORAL-PHARYNGEAL, SALIVARY GLANDS,
SUBMANDIBULAR
SEE ALSO GROVTFH FACTORS (INCL. ANABOLICS), EPIDERMAL
GROWTH FACTOR
R01HL-15839-05 Physiological role of isorenin and
kallikrein (animals)
R01HL-18019-04 The endocrine kidney in hypertension
(mice)
ORAL-PHARYNGEAL, SALIVATION
R01HL-20861-01 Cardlo-respiratory-renal stress reactions
(dogs)
ORAL SURGERY
P60HL-17292-04 0029 Vermont Lung Center - Computer-
assisted pre-operative evaluation (human)
(contd)
*Excludes routine methodology OR covers only general projects which preclude i
"Oriented signifnantly to above subject.
ndexing at the specific level.
1^ Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
' ■k^*-|ja'<T>£M:<iiJU*jUWMauwtfMBAAAAAi .
ORG
ORBITAL GYRI
SEE BRAIN, CEREBRUM, ORBITAL GYRI
ORGAN CULTURE
SEE TISSUE (CELL) CULTURE, ORGAN CULTURE
ORGAN PROSTHETIC
SEE PROSTHETIC ORGANS AND TISSUES
ORGAN TRANSPLANTATION
SEE TISSUE COMPATIBILITT-TRANSPLANT. TRANSPUNTATION
ORGANELLES
SEE CELL COMPONENTS, ORGANELLES
ORGANIC ACIDS
SEE ACIDS-BASES, ACIDS ORGANIC (GENERAL)
ORGANIC COMPOUNDS (GENERAL)
SEE CHEMICALS (GENERAL), ORGANIC COMPOUNDS
(GENERAL)
ORGANIC SYNTHESIS
SEE CHEMICAL SYNTHESIS AND PRODUCTION
ORGANIZATIONS, HEALTH SCIENCES
SEE HEALTH AND SCIENTIFIC ORGANIZATIONS
ORGANS
SEE TISSUE, ORGANS (SEE ALSO SPECIFIC ORGANS)
ORIENTATION, BODY POSITION
SEE SENSORY-PERCEPTUAL PROCESSES. PROPRIOCEPTION
ORIENTATION
SEE ENVIRONMENT. ORIENTATION
ORINASE
SEE SULFONYLUREA, TOLBUTAMIDE
ORNITHINE DECARBOXYLASE
SEE DECARBOXYLASES, ORNITHINE DECARBOXYUSE
ORNITHOSIS VIRUS
SEE CHLAMYDIA, PSIHACOSIS AGENT
OROTIC ACID
SEE PYRIMIDINES. OROTIC ACID
ORTHOPEDICS
SEE SKELETAL DISORDERS. ORTHOPEDICS
ORTHOPHENOLASE
SEE OXYGENASES, MONOPHENOL MONOOXYGENASE
ORTHOSTATIC HYPOTENSION
SEE CARDIOVASCUUR DISORDERS. HYPOTENSION POSTURAL
OSCILLATORY BLOOD FLOW
SEE CARDIOVASCULAR FUNCTION. BLOOD FLOW
OSCILLATORY
OSCILLOGRAPHY
SEE ELECTRICAL MEASUREMENTS. OSCILLOGRAPHY
OSMORECEPTORS
SEE SENSE ORGANS, OSMORECEPTORS
OSMOSIS
SEE BIOLOGICAL TRANSPORT. PASSIVE TRANSPORT, OSMOSIS
OSMOTIC FRAGILITY (BLOOD)
SEE BLOOD (HEMATOLOGIC) TESTS, OSMOTIC FRAGILITY*
OSMOTIC PRESSURE, BLOOD
SEE BLOOD OSMOTIC PRESSURE
OSMOTIC PRESSURE, BODY FLUIDS
SEE BODY FLUID BAUNCE, OSMOTIC PRESSURE
OSMOTIC PRESSURE, CELL FLUIDS
SEE CELL FLUIDS. OSMOTIC PRESSURE
OSMOTIC PRESSURE OF OTHER FLUIDS
SEE PHYSICAL PROPERTIES. FLUID STATE. OSMOTIC
PRESSURE
OSTEITIS DEFORMANS
SEE SKELETAL DISORDERS. OSTEITIS DEFORMANS
OSTEITIS TUBERCULOSA MULTIPLEX CYSTOIDES
SEE NEOPLASMS REUTED INTEREST. SARCOIDOSIS
OSTEOGENIC SARCOMA
SEE NEOPUSMS OF SKELETAL SYSTEM. OSTEOGENIC
SARCOMA
OSTEOMYELITIS
SEE SKELETAL DISORDERS. OSTEOMYELITIS
OSTEOPOROSIS
SEE SKELETAL DISORDERS. BONE METABOLISM,
OSTEOPOROSIS
OTITIS MEDIA
SEE EAR DISORDERS. MIDDLE EAR DISORDERS OTITIS
MEDIA
OUABAIN
SEE CARDIAC GLYCOSIDES. OUABAIN
392
OUTFLOW DISORDERS, HEART
SEE HEART DISORDERS, OUTPUT ABNORMALITIES
OUTPATIENT FACILITIES (GENERAL)
SEE HEALTH CARE FACILITIES, OUTPATIENT FACILITIES
OUTPATIENT FACILITIES (HOSPITAL)
SEE HOSPITALS. OUTPATIENT FACILITIES
OUTPUT ABNORMALITIES
SEE HEART DISORDERS, OUTPUT ABNORMALITIES
OUTREACH
SEE HEALTH CARE SERVICES, CASE FINDING AND OUTREACH
OVALOCYTOSIS HEREDITARY
SEE BLOOD AND RE DISORDERS. ANEMIA HEMOLYTIC
CONGENITAL. ELLIPTOCYTOSIS HEREDITARY
OVARY
SEE REPRODUCTIVE SYSTEM FEMALE. OVARY
OVERDOSE OF DRUGS
SEE DRUGS ABUSE, OVERDOSE
OVIS
SEE MAMMALS, ARTIOOACTYLA, SHEEP*
OVOTRANSFERRIN
SEE ALBUMINS. CONALBUMIN
OWL MONKEYS
SEE MAMMALS, PRIMATES, MONKEYS AND APES
(ANTHROPOIDS, NON-HUMAN), NEW WORLD MONKEYS
(PLATYRHINES)*
OXALACETATE
SEE DICARBOXYLIC ACIDS, OXALACETATE
OXALOACETATE TRANSACETASE
SEE OXO-ACID-LYASES, CITRATE (SI) SYNTHASE
OXAMATES
ROlHL-2011601 Heart lactate dehydrogenase-The complex
with NADH (pig)
OXANDROLONE
SEE ANDROSTANE SERIES, OXANDROLONE
OXAZINES, MORPHOLINES, DOXAPRAM
R23HL-20968-02 Respiratory failure-Control and muscle
dysfunction (human)
OXAZOLES
ROlHL-20579-02 Synthesis of therapeutically important
alkaloids
OXIDANTS
P01HL-16833-04 0014 Hemoglobin and red cell system in
hemoglobinopathies - Erythrocyte membrane damage in Mb
SS disease (human)
POlHL-16833-04 0016 Hemoglobin and red cell system in
hemoglobinopathies - Calcium-indiced membrane damage
in Hb SS disease (human, animals)
R23HL-22621-01 Blood cell-mediated pulmonary (human)
OXIDANTS, ANTIOXIDANTS
ROlHL-06481-15 Lipid metabolism (human, rats)
ROlHL-11897-11 Pathogenesis of experimental
atherosclerosis (rabbits, guinea pigs)
ROlHL-14663-07 Pulmonary oxygen toxicity in newborn
lung (human, mice)
ROlHL-16330-06 Aging-tissue injury and repair (rats)
ROlHL-16674-05 Airborne metals and lung permeability
(bullfrogs, rats)
ROlHL-19633-02 Pathogenesis and pharmacology of lung
fibrosis (rats, rabbits)
ROlHL-20352-02 Defenses of lung cells against oxygen
toxicity (human, animals)
ROlHL-21009-02 Effects of air pollutants on lung cells in
culture (rats)
OXIDASE INHIBITORS
SEE ENZYME INHIBITORS, OXIDOREDUCTASE INHIBITORS
OXIDATION
SEE OXIDATION-REDUCTION, OXIDATION
OXIDATION-REDUCTION
SEE ALSO CHEMICAL TRANSFER, ELECTRON TRANSPORT
SEE ALSO CHEMICAL TRANSFER, HYDROGEN TRANSPORT
SEE ALSO RESPIRATION INTERNAL
SEE ALSO RESPIRATORY GASES
POlHL-07896-15 0019 Environmental biomedical research
program • Hyperoxic myopia (human)
POlHL-07896-15 0051 Environmental biomedical research
program - Relationships of retinal circulation to disease
(rabbits)
ROlHL-1 1880-10 Physiology and pathology of blood
platelets (human, dogs)
R01HL-12647-08 Inactivation of norepinephrine in vascular
tissue
ROlHL-13581-11 Reactions of oxygen with heme proteins
ROlHL-13652-08 Metal sites in metalloproteins
(mushroom)
R0IHL14461-08 Cardiac metabolism in heart failure
(rats)
•Excluijes routine methodology OR covers only general projects which preclude indexing
Uriented significantly to above subject.
OXI
ROlHL-14483-08 Energy conservation in heart
mitochondria (cattle, E coli, human)
P60HL-15157-07 0012 Comprehensive center for sickle
cell disease - Sickling and intracellular pH (human)
** P50HL1 7670-04 0022 Study of ischemic heart disease -
Myocardial metabolism in hypoxia and recover (rabbit.
toad, dog)
POIHL- 18 708-03 0010 Oxygen, energy and contractility in
cardiac tissue - Tissue oxygen utilization (rats, dogs)
POlHL-19737-02 0008 Cellular and molecular aspects of
respiratory physiology - Kinetics of movement of acid
metabolites from cell to capillary blood (dogs)
ROlHL-20141-02 Biochemical approaches to management
of iron overload (human, sheep, dogs)
ROlHL-22315-01 Intraoperative cardiac oxygen supply-
demand (dogs, rabbits, rats)
ROlHL-22780-01 Factors modifying the reaction properties
of HgS (human)
OXIDATION-REDUCTION, AUTO-OXIDATION
ROlHL-15980-06 Reactions of hemeproteins and oxygen
(cattle)
ROlHL-16029-05 Bio-organic chemistry of ozone, nitrogen
dioxide and tobacco smoke
ROlHL-16927-05 Structure and function of normal and
abnormal hemoglobin (human)
*• POlHL-20993-02 0008 Population dynamics of arterial
cells in atherogenesis - Angiotoxicity of cholesterol
oxidation in atherogenesis (rabbits)
OXIDATION-REDUCTION, OXIDATION
SEE ALSO RESPIRATORY GASES. OXYGENATION
ROlHL-07379-13 Structure and function of fibrinogen
(human)
POlHL-08214-15 0006 Chemical and biological properties
of lipids - Analysis and properties of lipids
POlHL-08899-14 0055 Tolerance to respiratory gases in
health and disease - Oxygen effects on organ functions-
Extension of tolerance
** POlHL-08899-14 0062 Tolerance to respiratory gases in
health and disease - Influence of oxygen at high pressure
upon oxidation (rats)
ROlHL-09489-13 Myocardial lipid metabolism and
regulation (rats)
R01HL-13028-09 Regulation of myocardial fatty acid
metabolism (rats)
ROlHL-13302-09 Uptake and metabolism of lipids by the
liver (rats)
ROlHL-13412-17 Synthetic oxygen carriers
ROlHL-14730-07 Fatty acid beta-oxidation in normal and
ischemic hearts (rabbits)
•* P50HL-15061-07 0002 Response of lung to injury -
Oxidative metabolism, phospholipid synthesis, and response
to toxins (rats)
ROlHL-15622-05 Computer simulation in cardiology (rats,
dogs)
ROlHL-17896-03 Dehydropeptide renin substrates
ROlHL-18089-04 Fatty acid metabolism in heart and its
regulation (swine, rats)
ROlHL-18163-04 Red cell membrane effects due to
oxidizing agents
R0)HL-19491-03 Mechanism of iron storage and
mobilization by ferritin (horse)
POlHL-19737-02 0001 Cellular and molecular aspects of
respiratory physiology - Fatty acid metabolism in type II
alveolar cells (rats)
ROlHL-20125-02 Cyclic nucleotides and alveolar
macrophage activation (rabbits)
ROlHL-20909-02 Clofibrate-enhanced lipid oxidation by
peroxisomes (rats)
ROlHL-20996-02 Structural and reactivity of iron and
cobalt complexes
ROlHL-22951-01 Studies on the affect of vitamin E on
platelets (human, rats)
OXIDATION-REDUCTION, REDUCTION
P50HL-15061-07 0012 Response of lung to injury -
Hyperbaric oxygen, carbon monoxide, and ozone or peroxide
toxicity (rats)
OXIDATION-REDUCTION ENERGIES
SEE BIOLOGICAL TRANSPORT. TRANSPORT ENERGHICS
OXIDATIVE PHOSPHORYLATION
SEE ALSO PURINE NUCLEOTIDES, ADENINE NUCLEOTIDES
ATP
ROlHL-09364-14 Ion transport by heart mitochondria
(cattle, rat, rabbit)
R01HL-12997-07 Myocardial defects induced by potassium
depletion (human, rats, cats)
P50HL-14138-05 0015 Center for research on
atherosclerosis - Arterial wall -Intermediary metabolism,
enzynle activity and bioenergetics
P50HL-14212-07 0013 Correlated studies of pulmonary
fibrosis - Mechanism of beryllium pathogenicity in the lung
(human, rabbit, guinea pig)
P50HL-14217-08 0059 Specialized center of research in
thrombosis - Energy metabolism and platelet function
(human)
ROlHL-14483-08 Energy conservation in heart
mitochondria (cattle, E coli, human)
ROlHL-14730-07 Fatty acid beta-oxidation in normal and
ischemic hearts (rabbits)
at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
(contd)
OXI
ROIHL 1S01307 lung oxiditiv* mettbolism and eneigy
production (lodantsi labbits)
•" ROIHI 15104 07 A mechanism lot oxidative
phosptiorylation
ROIHL 1S622 OS Computer simulation in caidioloiy (rats.
dots)
POIHI 1583506 0011 Study ot muscles related lo heart
disease tnerjetics and mechanism ot muscle contraction
(tro|s. labbits)
•• POIHL 16251 06 0009 Membrane bound eniymes in heart
and other tissues NADH dehydrogenase and site I ot
oxidative phosphorylation (yeast)
*• ROlHl 16686 04 Properties of cytochrome oxidase (cattle,
bacteria)
P60H1. 1 7269 04 0018 National heart and blood vessel
research and demonstration center Mitochondria and
energetics (rabbits, dogs)
P50HL1767004 0022 Study ot ischemic heart disease
Myocardial metabolism in hypoxia and recover (rabbit,
toad, dog)
P50HL 17670 04 0023 Study of ischemic heart disease
Energy metabolism in acute myocardial ischemic iniury
(dogs)
P50HL17682 04 0018 Study ot ischemic heart disease
Biochemistry of ischemia Heart cell and organ culture
(mice, rats, cattle)
** R01HL1803803 Structure and (unction ot heart
mitochondria (cattle)
ROIHL 1820604 Regulation ot metabolism in oxygen
deficient hearts (rats)
P50HL19190-02 0007 Pulmonary SCOR-Pathophysiology.
management of IRDS Asphyxia-Cerebral merabolism (dog,
rat)
R01HL1939203 Spectroscopic studies of respiratory
metalloproteins
ROIHL 20143-02 Hypothermic circulatory arrest-Cerebral
vascular change (dogs)
ROlHL-20408-03 Hyperlipidemia in diabetics during
muscular training (human)
ROlHL-20484-03 Effects of diabetes on cardiac function
and metabolism (rats)
ROlHL-2054402 Integrated regulation of myocardial
energy metabolism (rats, guinea pigs)
ROlHL-2 1209-02 Alterations of metabolism in ischemic
myocardium (swine)
ROlHL-2314201 Mechanisms of membrane injury in
myocardial ischemia (dog)
ROlHL-23161-01 0001 Biology of myocardial ischemia -
Mitochondrial lipid metabolism and cardiac ischemia (rat,
dog)
ROlHL-23166-01 Pathology of mitochondria in ischemic
myocardium (rats, cattle)
ROlHL-23205-01 Contraction of pulmonary vascular
smooth muscle (cat)
OXIDES (SEE ALSO SPECIFICS)
SEE ALSO CARBON MONOXIDE
SEE ALSO ETHERS
SEE ALSO IRON OXIDES
SEE ALSO NITROGEN DIOXIDE
SEE ALSO NITROGEN OXIDES
SEE ALSO PEROXIDES
SEE ALSO RESPIRATORY GASES
ROlHL-13399-16 Heme protein structure and function
(human, horse, plants, bacteria)
OXIDES, EPOXIDES
ROlHL-02477-23 Biosynthesis and function of lipids
(microorganisms, rats)
ROlHL-14847-07 Mechanism of action of vitamin K and
anticoagulants (rats)
ROlHL-16471-05 Cardioactive alloyohimbines and related
indole alkaloids
P60HL-17269-04 0016 National heart and blood vessel
research and demonstration center - New analytical
methodology for atherosclerosis studies
ROlHL-20577-03 The mechanism of action of vitamin K
ROlHL-23 115-01 Regulation of active sodium transport
(frogs, rats)
OXIDOREDUCTASE INHIBITORS
SEE ENZYME INHIBITORS, OXIDOREDUCTASE INHIBITORS
OXIDOREDUCTASES
SEE ALSO FLAVOPROTEIN ENZYMES
SEE ALSO METABOLIC DISORDERS INBORN, ANGIONEUROTIC
EDEMA (HEREDITARY)
SEE ALSO METALLOPROTEINS, CERULOPLASMIN
SEE ALSO METALLOPROTEINS, CYTOCUPREINS
SEE ALSO NAD LINKED ENZYMES
SEE ALSO NADP LINKED ENZYMES
SEE ALSO OXYGENASES
SEE ALSO PEROXIDASES
** POlHL-07896-15 0049 Environmental biomedical research
program - Effects of hyperbaric oxygen and pressure on
cerebral enzymes (rats)
ROlHL-10894-12 Intestinal bacteria and steroid
metabolism (human, guinea pigs, rabbits, rats)
** ROlHL-1 16 14-11 Trace Clements in nutrition (chickens,
rats, human)
ROlHL-13399-16 Heme protein structure and function
(human, horse, plants, bacteria)
ROlHL-13645-11 Tryptophan-induced pulmonary
emphysema (cattle, goats, rabbits)
393
POIHI 16118 06 0003 Study of emphysema Degradation
of collagen and elastin (human, hamsters, mice)
ROIHL 19083 02 Rapid specific micro measurement of
blood cholesterol
•* POIHI 19717 02 0004 Response of the lung to iniury
Regulatory and physical chemical properties ot lung lysyl
oxidase (animals)
ROIHL 20577 03 The mechanism ot action of vitamin K
ROIHI 21303 02 Collagen synthesis by cultured human
vascular cells
OXIDOREDUCTASES, ACYL-COA
DEHYDROGENASE
ROIHL 18089 04 Fatty acid metabolism in heart and its
regulation (swine, rats)
ROIHL 20411 03 Platelet fatty acid metabolism in
diabetes (rat. rabbit, guinea pig)
OXIDOREDUCTASES, AMINE OXIDASE (FLAVIN
CONTAINING)
SEE ALSO ENZYME INHIBITORS. MONOAMINE OXIDASE
INHIBITORS
ROIHL 13315-08 Disposition of vasoactive hormones in
mammalian lung (rats, rabbits, human)
** ROIHL 17487 04 Adrenergic vasoregulation interactions in
hypertension (human)
OXIDOREDUCTASES, AMINE OXIDASE
(PYRIDOXAL-CONTAINING)
P50HL-191 57-02 0009 Studies in cystic fibrosis and
bronchiolitis Polyamine metabolism in cystic fibrosis
(human, rat)
OXIDOREDUCTASES, AMINO ACID OXIDASES
** POIHL 16251-06 0010 Membrane bound enzymes in heart
and other tissues Reversible activation of L-amino acid
oxidase (snakes)
OXIDOREDUCTASES, CYTOCHROME B5
REDUCTASES
POlHL-14388-07 0175 Regulation of the circulation in
pathological states - Functional studies of selected proteins
from cardiac muscle
OXIDOREDUCTASES, CYTOCHROME OXIDASES
POlHL-07896-15 0039 Environmental biomedical research
program Development of resistance to lethal effects of
oxygen (rats)
ROlHL-091 72-15 Protein and RNA synthesis in heart
muscle (rats)
P50HL-15061-07 0012 Response of lung to injury -
Hyperbaric oxygen, carbon monoxide, and ozone or peroxide
toxicity (rats)
POlHL-15835-06 0013 Study of muscles related to heart
disease - Cardiac bioenergetics (rats)
ROlHL-15980-06
(cattle)
ROlHL-16686-04
bacteria)
ROlHL-17559-03
Reactions of hemeproteins and oxygen
Properties of cytochrome oxidase (cattle,
M
Structural elucidation of heart
cytochrome-C oxidase
ROlHL-18157 04 Subcellular events in atherosclerosis
(human, rabbits, calves)
POIHL 18708-03 Oxygen, energy and contractility in
cardiac tissue
'* POlHL-18708-03 0003 Oxygen, energy and contractility in
cardiac tissue - Structural-functional studies on cytochrome
c oxidase
POlHL-1870803 0009 Oxygen, energy and contractility in
cardiac tissue - Regulation of oxygen utilization of cardiac
tissue (rats, rabbits)
POlHL-18708-03 0010 Oxygen, energy and contractility in
cardiac tissue - Tissue oxygen utilization (rats, dogs)
ROlHL-19392-03 Spectroscopic studies of respiratory
metalloproteins
ROlHL-19425-03 Cardiac function in hypertrophy (dog)
" POlHL-20592-02 0011 Cell biology of cardiac and
skeletal muscle - Myosin and cytochrome oxidase
messenger RNAs (chicken)
ROlHL-22050-01 Organization of succinic oxidase in heart
ROlHL-221 74-01 Assembly of membranes in heart and
yeast mitochondria
ROlHL-22333-01 Cellular basis of small airways function
(rats)
OXIDOREDUCTASES, DEHYDROGENASES
ROlHL-02477-23 Biosynthesis and function of lipids
(microorganisms, rats)
ROlHL-14456-07 Lung metabolism-Enzymes in the
pulmonary circulation (human, animals)
POlHL-1738205 0003 Chemical mediators of acute
pulmonary disorders - Chemical mediators relevant to
allergic reactions (human, guinea pigs)
ROlHL-18259-03
prostaglandins
ROlHL-20878-02
rabbits)
ROlHL-21912-01
Controlled intratissue release of
Cellular aspects of lung injury (rats,
Biosynthesis of lipoic acid and
atherosclerosis (birds, chick embryos)
OXIDOREDUCTASES, GLUCOSE OXIDASE
ROlHL-17967-04 Limiting factors in oxygen uptake in the
lung
OXI
OXIDOREDUCTASES, GlUCOSE-6-PHOSPHATE
DEHYDROGENASE
SEE ALSO Mf lABOIIC OlSORDf RS INBORN, (ilUCOSt fc
PHOSPHAtf 0(HYOROG(NASr DIflCIFNCY
•* POIHL 031/4 23 0006 Mechanism-, o( jcule vascular
reaction lo iniury Atherosclerotic plaque -.ludiev using
mosaic analysis (human)
•• ROIHL 1213808 Nutritional regulation of en/yme activity
(rats, human)
ROIHI 15125 07 Molecular pathology ot genetic disorders
in man
POIHL 1674805 0004 Cellular and immunological basis
of pulmonary diseases Cellular and immunological
processes in pulmonary defense systems
ROIHL 17719-03 Lung injury, substrate utilization, oxygen
toxicity (rats, rabbits, dogs)
*• ROIHL 1850203 Enzymatic regulation of platelet function
(human)
POIHL 21016 02 0011 Sickle cell anemia and other
hemoglobinopathies Metabolic effects of anii sickling
agents (hamsters)
OXIDOREDUCTASES, GLUTATHIONE REDUCTASE
POIHL 16833-04 0016 Hemoglobin and red cell system in
hemoglobinopathies Calcium indiced membrane damage
In Hb SS disease (human, animals)
ROlHL-17719-03 Lung injury, substrate utilization, oxygen
toxicity (rats, rabbits, dogs)
** R01HL1850203 Enzymatic regulation of platelet function
(human)
POIHL 21016 02 0011 Sickle cell anemia and other
hemoglobinopathies Metabolic effects of anti-sickling
agents (hamsters)
OXIDOREDUCTASES, GlYCERALDEHYDE
PHOSPHATE DEHYDROGENASE
ROIHL 18206-04 Regulation of metabolism in oxygen
deficient hearts (rats)
ROlHL-19933-02 Membrane and red cell dysfunction in
hemolytic anemia (human)
OXIDOREDUCTASES, GLYCEROPHOSPHATE
DEHYDROGENASE
P01HL-07896 15 0049 Environmental biomedical research
program - Effects of hyperbaric oxygen and pressure on
cerebral enzymes (rats)
ROlHL-15013-07 Lung oxidative metabolism and energy
production (rodents, rabbits)
** ROlHL-18567-03 A routine diagnostic test for minimal
heart damage (human, rat)
OXIDOREDUCTASES, HMG-COENZYME A
REDUCTASE
** ROlHL-05360-19 Cholesterol biosynthesis and its control
in liver (rats)
POlHL-06285-18 0207 Cardiovascular-respiratory
physiology and biochemistry - Feedback control of
cholesterol synthesis in non-hepatic tissues (animals)
ROlHL-06481-15 Lipid metabolism (human, rats)
ROlHL-08534-15 Enzymic cholesterol synthesis (human.
rats, protozoa, yeast)
R01HL-12745-10 Enzymes and inhibitors of cholesterol
biosynthesis (rats, human, swine)
ROlHL-14781-08 Lipid deposition in mammalian cells
(mice)
ROlHL-15895-05 In vitro study of lipoproteins in vascular
disease (human, animals)
ROlHL-15930-06 Hormonal control of lipid and lipoprotein
synthesis (rats)
** ROlHL-16294-04 Effectors ot cholesterol synthesis (rats)
** ROlHL-16364-O'l Regulation of lipid biosynthesis and
transport (rats, swine, Xenopus)
** ROlHL-16796-05 Cholesterol regulation by HMG-CoA
reductase (rats, human)
P60HL- 17269-04 0045 National heart and blood vessel
research and demonstration center Regulation of
lipogenesis in hypertipoproteinemia (human, tissue culture)
ROlHL-17818-05 Metabolism of cholesterol and cholesterol
in man (also rats, monkeys)
** ROlHL-17882-04 Regulation of HMG-COA reductase and
sterol synthesis (human, mammals)
*• ROlHL-18094-04
(rats)
Regulation of cholesterol biosynthesis
Regulation of cholesterol metabolism
ROlHL-18219-04
(rats)
ROlHL-18878-03 Familial hypercholcsteremia-Studies of
fibroblasts (human)
ROlHL-19063-03 Cholesterol and lipoprotein metabolism
(rat hepatocytes)
ROlHL-19223-03 Control of cholesterogenesis in leukocytes
and liver (rats, human)
ROlHL-20428-03 The juvenile diabetic heart (human)
ROlHL-20807-02 Detection of familial hypercholesterolemia
(human)
POlHL-20948-02 0001 Molecular basis of cholesterol
metabolism - Biochemical and ultrastructural
characterization of LDL in human fibroblasts
POlHL-20948-02 0002 Molecular basis of cholesterol
metabolism - LDL pathway in cell lines with informative
properties other than fibroblasts
POlHL-20948-02 0003 Molecular basis of cholesterol
metabolism - LDL pathway in vivo (human, rats, guinea
pigs)
(contd)
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
••Oriented significantly to above subject.
M Grant has subproiects describing specific research aspects.
See Appendix for investigator's name and grant number.
OXI
POlHL-20993-02 0004 Population dynamics of arterial
cells in atherogenesis - Modifications of cholesterol balance
related to arterial cell divisions (swine)
ROlHL-21246-02 Roles of cholesterol and its metabolic
regulation (CHO cell mutants)
ROlHL-22532-01 Inhibitors of cholesterol biosynthesis
(rats, mice, yeast)
POlHL-2263301 0002 Cellular and molecular biology of
lipoprotein metabolism ^ Sterol metabolism in tissue
culture cells
OXIDOREDUCTASES, BETA-HYDROXYBUTYRATE
DEHYDROGENASE
R01HL16660-06 Phospholipid-cholesterol and
phospholipid-protein interactions
OXIDOREDUCTASES, ISOCITRATE
DEHYDROGENASE
R01HL18143-03 Surgery and pulmonary tissue alterations
(dogs, rats, human)
OXIDOREDUCTASES, LACTATE DEHYDROGENASE
SEE ALSO OXIDOREDUCTASES, DLACTATE DEHYDROGENASE
POlHL-06312-17 0053 Surgical cardiology - Enzyme
pattern following cardiac surgery (human)
POIHL 12373-10 0001 Cardiopulmonary physiology and
pathophysiology - Mechanics of myocardial contraction
(dogs, rats, swine)
P50HL1 7648-04 0023 Study of ischemic heart disease -
Chemical mediators of inflammation in acute myocardial
infarction (mammals)
P50HL-1767004 0017 Study of ischemic heart disease -
Core enzymology laboratory (human)
P50HL-17682-04 0010 Study of ischemic heart disease -
Core clinical enzyme laboratory (human, mice, dogs, rats)
ROlHL-18143-03 Surgery and pulmonary tissue alterations
(dogs, rats, human)
R01HL-20n6-01 Heart lactate dehydrogenase -The complex
with NADH (pig)
ROIHL 20352-02 Defenses of lung cells against oxygen
toxicity (human, animals)
** POlHL-20552-02 0010 The development and regression of
cardiac hypertrophy - Energy metabolism in the
hypertrophied heart animals
POlHL-22602-01 0001 Pathophysiology of the
endothelium ■ Plateletendothelial interactions in vitro
(human, cattle)
OXIDOREDUCTASES, D-LACTATE
DEHYDROGENASE
POlHL-12157-11 0051 Functions and mechanisms of cell
membrane ion transport - Electron transport in the red cell
membrane (human, guinea pigs)
OXIDOREDUCTASES, MALATE DEHYDROGENASE
R01HL1258510 Structural properties of malate
dehydrogenase (swine)
** ROlHL-13035-08 Heart mitochondrial malate
dehydrogenase regulation
P50HL17682-04 0010 Study of ischemic heart disease -
Core clinical enzyme laboratory (human, mice, dogs, rats)
OXIDOREDUCTASES, MONOAMINE OXIDASE
SEE ALSO ENZYME INHIBITORS. MONOAMINE OXIDASE
INHIBITORS
ROlHL-0835914 Morphopharmacology of vascular
adrenergic transmission (rabbits, rats)
R01HL1318709 Central neural control of cardiovascular
function (cats)
POlHL-1625106 0007 Membrane-bound enzymes in heart
and other tissues - Flavins and flavoproteins
ROIHL 17907-04 Brain regulation of cardiac arrhythmia
(pigs, cats, rats)
ROIHL 2043902 Effects of insulin on neurovascular
transmission (human, rats, rabbits, hamsters)
R23HL-2132702 Molecular mechanisms of chemical
myocardiopathies (rats)
ROlHL-22077-01 Vasoactive amine disposition in cultured
endothelium (rabbits)
ROlHL-2257301 Treatment of post surgical
vasoconstriction (dogs, monkeys, human, rats)
OXIDOREDUCTASES, NAD(P)H
DEHYDROGENASE (QUINONE)
ROlHL-12576-10 Bioenergctics apparatus in heart
mitochondria
ROlHL-22981-17 Membrane-associated functions in
microorganisms (bacteria, protozoa)
OXIDOREDUCTASES, NADPH DEHYDROGENASE
ROlHL-13585-05 Heterogeneity of NADH methemoglobin
reductase (human)
P01HL16251-06 0009 Membrane-bound enzymes in heart
and other tissues - NADH dehydrogenase and site I of
oxidative phosphorylation (yeast)
OXIDOREDUCTASES, NADPH2 CYTOCHROME C
REDUCTASE
ROlHL-13619-09 Microsomal electron transport in liver
and heart (human, mammals)
P01HL14388-07 0175 Regulation of the circulation in
pathological states - Functional studies of selected proteins
from cardiac muscle
394
R23HL1960501 Lipid requirement of the lung mono-
oxygenase system (rabbits)
OXIDOREDUCTASES, OXOGLUTARATE
DEHYDROGENASE
POlHL-07896-15 0049 Environmental biomedical research
program • Effects of hyperbaric oxygen and pressure on
cerebral enzymes (rats)
ROIHL 20544-02 Integrated regulation of myocardial
energy metabolism (rats, guinea pigs)
OXIDOREDUCTASES, PHOSPHOGLUCONATE
DEHYDROGENASE
P01HL16748-05 0004 Cellular and immunological basis
of pulmonary diseases Cellular and immunological
processes in pulmonary defense systems
OXIDOREDUCTASES, PROSTAGLANDIN
SYNTHASE
P50HL-141 53-07 0012 Johns Hopkins Lung Center -
Chronic diseases of airways - Aspirin intolerance in
reversible lung disease (human)
R01HL18932-03 Brain microcirculation observed in vivo
after trauma (mice)
ROlHL-1913404 Angiotensin, prostaglandins, adrenergic
interactions (rats, rabbits)
P50HL-1915602 0005 Pulmonary SCOR-Chronic diseases
of airways - Vagal receptors in the airway -Epithelial injury
and antigen (dog, cat, rabbit)
R01HL1921803 Local regulation of coronary flow by
prostaglandins (rabbits)
ROlHL-20794-02 Prostaglandin synthesis in human
platelets (also in sheep, rabbit)
R23HL-2230901 Cardiovascular pharmacodynamics in
immature dogs
R23HL-22438-01 The etiology of genetic hypertension
(rats)
OXIDOREDUCTASES, PYRUVATE
DEHYDROGENASE
POlHL-0889914 0055 Tolerance to respiratory gases in
health and disease - Oxygen effects on organ functions-
Extension of tolerance
ROlHL-18143-03 Surgery and pulmonary tissue alterations
(dogs, rats, human)
OXIDOREDUCTASES, PYRUVATE OXIDASE
R01HL16101-05 Protein-lipid interaction (bacteria,
models)
OXIDOREDUCTASES, SUCCINATE:(ACCEPTOR)
OXIDOREDUCTASE
P01HL07896-15 0049 Environmental biomedical research
program Effects of hyperbaric oxygen and pressure on
cerebral enzymes (rats)
ROlHL-12576-10 Bioenergetics apparatus in heart
mitochondria
POlHL-16251-06 0002 Membrane-bound enzymes in heart
and other tissues ■ Structural basis of regulation of
cardiac succinate dehydrogenase
P01HL16251-06 0003 Membrane-bound enzymes in heart
and other tissues - Regulation of cardiac succinate
dehydrogenase (yeasts, mammals)
POlHL-1625106 0004 Membrane-bound enzymes in heart
and other tissues - Biosynthesis and degradation of
succinate dehydrogenase, histidyl (yeast, mammal)
POlHL-1625106 0008 Membrane-bound enzymes in heart
and other tissues ■ Iron-sulfur centers and phospholipids
modulation of succinate dehydrogenase
ROlHL-2205001 Organization of succinic oxidase in heart
02 OXIDOREDUCTASE
SEE OXYGENASES
OXIMETRY
SEE RESPIRATORY GAS ANALYZERS. OXIMETRY*
OXINS, PYRANS
ROlHL-21367-02 Polyether ionophores -Synthesis of X537A
and analogs
OXO-ACID-LYASES, CITRATE (SI) SYNTHASE
R01HL18143-03 Surgery and pulmonary tissue alterations
(dogs. rats, human)
OXOARYLS, LACTONES
SEE ALSO BENZO-ALPHA-PYRONES
ROlHL-17896-03 Dehydropeptide renin substrates
OXOGLUTARATE DEHYDROGENASE
SEE OXIDOREDUCTASES, OXOGLUTARATE DEHYDROGENASE
OXOLES, CHLORALOSE
ROlHL-1925603 Arterial baroreceptors in cardiovascular
control (dogs)
OXOLES, FURANS
POlHL-082 14-15 0048 Chemical and biological properties
of lipids - Lipids in microorganisms and plants
ROlHL-21367-02 Polyether ionophores-Synthesis of X537A
and analogs
OXYGEN
SEE RESPIRATORY GASES, OXYGEN
•Excludes routine methodology OR covers only general prolects which preclude indexing
Oriented significantly to above subject.
at the specific level.
M Grant has subprojects describing specific research aspects
See Appendix for investigator's name and grant number.
OXY
OXYGEN ADMINISTRATION
SEE RESPIRATORY ASSIST AND OXYGEN ADMINISTRATION
OXYGEN CONSUMPTION
SEE RESPIRATORY GAS CONSUMPTION, OXYGEN
CONSUMPTION
OXYGEN DEFICIENCY
SEE RESPIRATORY GAS LEVELS, HYPOXIA
OXYGEN INHALATION THERAPY
SEE RESPIRATORY ASSIST AND OXYGEN ADMINISTRATION
OXYGEN INHALATION THERAPY
OXYGEN POISONING
SEE RESPIRATORY ASSIST AND OXYGEN ADMINISTRATION,
HYPEROXIA
OXYGEN RADIOISOTOPES (15)
SEE RADIOISOTOPES, OXYGEN
OXYGEN TENSION
SEE RESPIRATORY GAS LEVELS, OXYGEN TENSION
OXYGEN TRANSPORT
SEE RESPIRATORY GAS TRANSPORT, OXYGEN TRANSPORT
OXYGENASES
R01HL-13157-09 Molecular oxygen carriers-Synthesis,
structure, bonding
P50HL-14147-08 0001 Specialized center of research in
thrombosis ■ Role of aspirin, other anti-platelet agents in
platelet function (rat. human)
R01HL16634-13 Regulation of metabolism in fibroblasts
and platelets (human, rabbits, sheep)
R01HL17516-04 Role of androgen as a risk factor in
atherogenesis (human, animals)
R01HL18718-04 Prostaglandin precursors and vascular
reactivity (dogs)
POlHL-19737-02 0009 Cellular and molecular aspects of
respiratory physiology - Regulation of tissue oxygen tension
and body carbon monoxide stores (human, dogs)
ROlHL-21 159-02 Pathophysiological effects of hypoxia
(rats)
ROlHL-22225-01 Hormonal regulation of blood pressure
and blood flow (human, animals)
OXYGENASES, DOPAMINE (BETA)-
MONOOXYGENASE
" POlHL-1438807 0194 Regulation of the circulation in
pathological states - Dopaminebeta-hydroxylase localization
and release in hypertension
ROIHLI 748704 Adrenergic-vasoregulation interactions in
hypertension (human)
ROlHL-18095-04 Human dopamine-beta-hydroxylase (also
cattle)
P50HL 1832304 0041 SCOR hypertension center -
Measurement of sympathetic response in hypertensive
patients
P01HL18974-03 0012 Experimental neurogenic
hypertension program - Immunohistocheraistry of central
monoamine neurons (rats)
R01HL1925103 An index of sympathetic activity in
hypertension (rats)
R01HL19644-03 Etiological factors in hypertension
(human, dogs, rats)
POlHL-20581-01 0006 Vascular neuroeffecfor
mechanisms in health and disease - Neuroeffecfor
mechanism in arteries and veins in hypertension (human)
ROlHL-21817-01 Catecholamines, blood pressure and
circulation
ROlHL-22547-01 Behavioral treatment of Raynaud's
disease (human)
OXYGENASES, HYDROXYLASES (GENERAL)
" POlHL-06835-17 0050 Cardiovascular disease ■ 18-
Hydroxylase block in the 17 alphahydroxylase deficiency
syndrome (human)
ROlHL-0787816 Metabolism of neutral sterols (rats.
rabbits)
P01HL14414-07 0016 Environmental influences on
cardiorespiratory and cellular functions - Effects of
pressure on membrane and cellular function (human
rabbits)
R01HL16364-04 Regulation of lipid biosynthesis and
transport (rats, swine. Xenopus)
R01HL16904-03 Regulation of smooth muscle cells in
arteriosclerosis (rabbit aorta)
R23HL19605-01 Lipid requirement of the lung mono-
oxygenase system (rabbits)
ROlHL-2130302 Collagen synthesis by cultured human
vascular cells
R23HL-22383-01 Biosynthesis-Response to oxygen
depletion (human, primates, rats)
OXYGENASES, HYDROXYLASES, ARYL
HYDROCARBON HYDROXYLASE
POlHL-03174-23 0011 Mechanisms of acute vascular
reaction to injury - Mutagen metabolism by artery wall in
etiology of atherosclerosis (human, animals)
ROlHL-2 II 56-02 Antitrypsin and other causes of chronic
lung disease
(contd)
OXY
OXYGENASES, IIPOXYOENASE
ROIHL 19806 03 Ch«mot«ctic control of airway phagocytes
(human, rabbits)
OXYGENASES, MIXED FUNCTION (GENERAL)
ROIHI 15013 0/ lung oxidative metabolism and energy
production (rodents, rabbits)
•• P50HL 19W0 02 OOOS Harvard pulmonary SCOR Chronic
diseases ol the airways Pulmonary toxicology ol plastics
Intermediates and pyrolysis products (animal)
•* R23HL 1960501 Lipid requirement ol the lung mono
oxygenase system (rabbits)
*• R01Hl'196&4 03 Biochemical pharmacological evaluation
ol lung cells (rabbits)
OXYGENASES, MONOPHENOl
MONOOXYGENASE
ROIHL 13652 08 Metal sites in metalloproteins
(mushroom)
OXYGENASES, STEROID MONOOXYGENASES
(GENERAL)
R01HL0?878 16 Metabolism of neutral sterols (rats.
rabbits)
ROIHL 17818-05 Metabolism ot cholesterol and cholesterol
in man (also rats, monkeys)
OXYGENASES, TRYPTOPHAN 2,3-DIOXYGENASE
R01HL13399 16 Heme protein structure and (unction
(human, horse, plants, bacteria)
R23HL 22383 01 Biosynthesis -Response to oxygen
depletion (human, primates, rats)
OXYGENASES, TRYPTOPHAN 5-
MONOOXYGENASE
** POlHL-18974-03 0011 Experimental neurogenic
hypertension program - Biochemistry and regulation of
btain tryptophane hydroxylase (rats)
POlHL-18974-03 0012 Experimental neurogenic
hypertension program Immunohistochemistry of central
monoamine neurons (rats)
OXYGENASES, TYROSINE 3-MONOOXYGENASE
POlHL-14388-07 0193 Regulation of the circulation in
pathological states - Ontogenesis of central nervous system
amines in hypertension (rats)
ROIHL- 17 706-04 Psychosocial hypertension,
catecholamines and drugs (mice)
ROIHL 18148-04 Adrenal catecholamine secretion
•* POlHL-18974-03 0009 Experimental neurogenic
hypertension program - Biochemistry of brain tyrosine
hydroxylase (rats)
POlHL-18974-03 0012
hypertension program
Experimental neurogenic
Immunohistochemistry of central
monoamine neurons (rats)
ROlHL-20604-03 Sympathectomy-Cardiovascular and
molecular pharmacology (animals)
ROlHL-20768-02 Mechanisms of circulatory regulation in
heart failure (guinea pigs)
R23HL-21973-01 Catecholamine metabolism and the heart
(human, guinea pigs)
OXYGENATION
SEE RESPIRATORY GASES. OXYGENATION
OXYGENATORS, BLOOD
SEE CARDIOVASCUUR SURGERY. CIRCULATORY ASSIST.
BLOOD OXYGENATORS
OXYGENATORS, PUMP BLOOD
SEE CARDIOVASCUUR SURGERY. CIRCULATORY ASSIST.
HEART MECHANICAL EXTRACORPOREAL
OXYGENATORS, RESPIRATORY
SEE RESPIRATORY ASSIST AND OXYGEN ADMINISTRATION
OXYHEMOGLOBIN
SEE HEMOPROTEINS. HEMOGLOBIN. OXYHEMOGLOBIN
OXYPURINES
SEE PURINES. OXYPURINES
OXYTOCIN
SEE PITUITARY-OIENCEPHALON HORMONES. OXYTOCIN
OZONE
SEE GAS ELEMENTS. OZONE
P-113
SEE PEPTIDES. OLIGOPEPTIDES, SARALASIN
PACEMAKERS
SEE BRAIN STIMULATORS ELECTRONIC
SEE ELECTRONIC STIMULATORS (GENERAL)
SEE HEART. CONDUCTION SYSTEM. HEART PACEMAKERS
SEE NEUROMUSCULAR STIMULATORS (FOR NEUROMOTOR
DISORDERS)
PAIN
SEE SENSORY-PERCEPTUAL PROCESSES. PAIN
PAIN RELIEVING AGENTS
SEE NEUROPHARMACOLOGICAL AGENTS. ANALGESICS
PALATE
SEE ORAL-PHARYNGEAL. PALATE
395
PALMITIC ACID
SH lAIlY ACIDS. PAIMIIIC ACID
N-PALMITOYLSPHINGOSINE
SEf SPHINGOLIPIDS. CfRAMIDL
PAN
SEE MAMMAIS, PRIMAIfS. MONKEYS AND APES
(ANIHROPOIDS, NON HUMAN). GREAT APES (PONGIOS).
PAN (CHIMPAN/ff)*
PAN AMERICAN HEALTH ORGANIZATION
(WHO)
SEE HEALTH AND SCIENTIFIC ORGANIZATIONS,
INTERNATIONAL. WHO
PANCREAS
ROIHL 11945-10 Synthesis of artificial lung and kidney
systems (sheep, mice, swine)
** ROIHL 19977 02 Genesis ot circulatory shock by
pancreatic peptides (cats, dogs)
PANCREAS, PANCREATIC ENZYMES
SEE ALSO GASTROINTESTINAL HORMONES. PANCREOZYMIN-
CHOLECYSTOKININ
SEE ALSO LIPASES. TRIACYLGLYCEROL LIPASE
SEE ALSO PROTEASES AND PEPTIDASES. CARBOXYPEPTIOASE
SEE ALSO PROTEASES AND PEPTIDASES. CHYMOTRYPSIN
SEE ALSO PROTEASES AND PEPTIDASES, TRYPSIN
ROIHL 02033 23 Regulation of cholesterol esters in blood
and tissues (rat, cattle, human)
ROlHL-17332-04 Use of the gut for therapy of coronary
artery disease (mammals)
PANCREAS DISORDERS, PANCREATITIS
ROlHL-14592-06 Alpha 1 antitrypsin deficiency and
pulmonary disease (human)
ROIHL 16603-05 Human and experimental renal diseases
(animals)
PANCREAS HORMONES
POIHL 08682 15 0019 Regulation of the cardiovascular
system Hepatic immunophysiology and host-defense in
shock (rat, dog, human)
ROlHL-14990-07 Lipid transport in avian species
(chickens)
PANCREAS HORMONES, GLUCAGON
ROlHL-01015-27 Hypertension and left ventricular
hypertrophy (dogs)
POlHL-06285-18 0149 Cardiovascular-respiratory
physiology and biochemistry - Microangiopathy in
prediabetic and diabetic subjects (human)
ROlHL-08659-14 Myocardial performance and metabolism
in the newborn (sheep)
POlHL-11310-12 0079 Mechanisms of cardiovascular
disease - Electrophysiological studies of complete heart
block (human)
POlHL-11414-11 0014 Thrombosis and atherosclerosis
program - Role of adrenal in human essential hypertension
** ROlHL-12085-10 Lipoprotein-carbohydrate metabolism
(human, rats)
ROIHL 13694-08 Capillary basement membrane in
cardiovascular disease (human, rats)
ROlHL-13715-08 Myocardial adenyl cyclase (rats)
P50HL-14230-07 0094 A/S SCOR -Lipids, atherosclerosis
and thrombosis - Studies of atherosclerosis and regression
Fetal hearts in organ culture (mice)
Hormonal control of lipid and lipoprotein
Splanchnic hemodynamics in man
Adrenal catecholamine secretion
Cardiovascular pharmacology of
(monkeys)
ROlHL-14706-07
ROlHL-15930-06
synthesis (rats)
ROlHL-16364-04 Regulation of lipid biosynthesis and
transport (rats, swine, Xenopus)
ROlHL-16656-06 Left ventricular function in exercise
(dogs)
ROlHL-180 20-04
ROlHL-18148-04
ROlHL-18599-02
ionophores (dogs)
ROlHL-18705-03 Regulation of plasma triglyceride
metabolism (rats)
POlHL-18827-02 0001 Platelet vessel wall interactions in
thrombogenesis - Role of endothelial cells in the production
of thrombi (human, cattle)
ROlHL-19223-03 Control of cholesterogenesis in leukocytes
and liver (rats, human)
ROlHL-20 183-02 Portacaval shunt as treatment for
hyperlipemia (pigs)
ROlHL-20476-03 Effects of diabetes on cardiac
performance (rat)
ROlHL-20483-03 Sterol balance and cholesterol absorption
in diabetics (human)
POlHL-20984-02 0005 Cellular mechanisms In cardiac
hypertrophy - Neurohumoral receptors in cardiac growth
and compensatory hypertrophy (animals)
R01HL-2U40-01 Studies of pulmonay alveolar
macrophage function (rabbits)
ROlHL-21272-02 Sodium homeostasis and renal
prostaglandins (dogs)
ROlHL-22101-02 Hormone-substrate interaction in diabetic
myocyte (dogs, rats)
ROlHL-22561-01 Hormonal control of mesenteric
circulation (cats)
PAN
POIHI 22619 01 0010 Cellular merhmnm* ot heart
(allure Mitochondria in heart and smooth muicle (libbrti.
rats, dogs)
ROIHL 22812 01 Regulation of hepatic production of HDL
(rats)
PANCREAS HORMONES, INSULIN
SEE ALSOCARBOHYORAltS MEIABOLISM DISORDERS,
DIABETES
SEE ALSO PANCREATIC ISLETS DISORDERS.
HYPERINSULINISM
ROIHL 00340 29 Electrolyte disturbance in cardio renal
disease (human, dogs, rats)
** ROIHL 01813 25 Regulation of metabolism by drugs and
hormones (rats)
ROIHL 02063 23 Biochemistry and function of lipids and
cell membranes (human, yeast, animals)
POIHL 06285 18 0149 Cardiovascular respiratory
physiology and biochemistry Microangiopathy in
prediabetic and diabetic subjects (human)
" R01HL08506 15 Lipemia carbohydrate and glyceride
metabolism (human, rats)
ROIHL 08659 14 Myocardial performance and metabolism
in the newborn (sheep)
POlHL-08682 15 0020 Regulation of the cardiovascular
system Hepatic metabolic basis of shock (rat)
POIHL 08682 15 0021 Regulation of the cardiovascular
system Hypoglycemia in pathogenesis of shock (dog)
ROIHL 09489-13 Myocardial lipid metabolism and
regulation (rats)
POlHL-1 1310-12 0063 Mechanisms of cardiovascular
disease Myocardial function, metabolism and cellular
integrity after heart surgery (dogs)
ROlHL-1 1551-11 RNA and protein synthesis in repair o(
heart injury (mice, rats)
ROIHL 12085 10 Lipoprotein-carbohydrate metabolism
(human, rats)
POlHL-12373-10 0012 Cardiopulmonary physiology and
pathophysiology Biochemistry of the sympathetic nervous
system (rats, rabbits, pigeons)
ROlHL-12869-09 Arterial metabolism, diabetes and
atherogenesis (rats, rabbits)
ROlHL-12974-10 Tracer kinetics, flows and masses in
body organs (human, dogs)
ROlHL-13029-09 Metabolic regulation o( sugar transport
(pigeons, rats)
ROlHL-13193-09 Pathophysiology of posttraumatic and
shock states (rodents, dogs)
ROlHL-13405-09 Regulation of lipid metabolism in the
lung (rats)
ROlHL-13694-08 Capillary basement membrane In
cardiovascular disease (human, rats)
P50HL-14138-05 0008 Center for research on
atherosclerosis - Core lipid laboratory (human)
P50HL-14141-05 0008 SCOR for atherosclerosis in
childhood - Core laboratory
ROlHL-14706-07 Fetal hearts in organ culture (mice)
POlHL-14985-07 0012 Adaptation to hypoxia - Direct
effect o( hypoxia on pulmonary vascular smooth muscle
(rats, dogs)
ROlHL-15013-07 Lung oxidative metabolism and energy
production (rodents, rabbits)
ROlHL-15427-06 Secretion of plasma lipoproteins (rats)
ROlHL-15813-05 Cardiac anoxia -Protective effect o(
carbohydrate (dogs)
ROlHL-15930-06 Hormonal control ot lipid and lipoprotein
synthesis (rats)
ROlHL-15985-06 Metabolic and hormonal control o(
cardiac contraction
ROlHL-16364-04 Regulation o( lipid biosynthesis and
transport (rats, swine, Xenopus)
ROlHL-16567-04 DKterentiation o( the heart-cell
membrane (mice, chick)
R01HL16577-04 Lipoprotein lipase chemistry and (unction
(rats, cattle, human)
P50HL- 17667-04 0040 Study o( ischemic heart disease -
Core biochemistry-Cardiac metabolism (human)
ROIHL 18185-04 Cardiac glycosides and diuretics-Role o(
NaO pump (dogs)
ROlHL-18537-04 Regional blood (low after acute
myocardial injury (dogs)
** ROlHL-18705-03 Regulation o( plasma triglyceride
metabolism (rats)
POlHL-18827-02 0001 Platelet vessel wall interactions in
thrombogenesis - Role o( endothelial cells in the production
o( thrombi (human, cattle)
ROlHL-18938-03 Pulmonary (atty acid and phospholipid
metabolism (rats)
ROlHL-19195-03 Hormonal regulation of lung (unction
(rats)
ROlHL-19223-03 Control o( cholesterogenesis in leukocytes
and liver (rats, human)
ROlHL-19669-03 Lung organ culture and surfactant
biosynthesis (adult and (etal rats)
ROlHL-19752-03 Phospholipid synthesis by fetal lung in
organ culture (rats)
R01HL-20183-02 Portacaval shunt as treatment (or
hyperlipemia (pigs)
ROlHL-20388-03 Regulation o( protein turnover in diabetic
heart (rat)
** ROlHL-20401-03 Relationship o( insulin to catechol
cardiomyopathy (rabbit, pig)
(contd)
'Excludes routine methodology OR covers only general projects which preclude
"Oriented signiticantly to above subject.
indexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix tor investigator's name and grant number.
PAN
ROlHL-2041803 S«rum cholesterol binding reserve in
diabetes (human)
ROlHL-20439-02 Effects of insulin on neurovascular
transmission (human, rats, rabbits, hamsters)
ROlHL-20476-03 Effects of diabetes on cardiac
performance (rat)
ROlHL-2048303 Sterol balance and cholesterol absorption
in diabetics (human)
ROlHL-20488-03 Cholesterol metabolism in diabetic man
ROlHL-2050803 Diabetes, hyperglycemia and
cardiovascular disease (human)
POlHL-20552-02 0001 The development and regression of
cardiac hypertrophy - Biochemical events in cardiac
hypertrophy (rats)
POlHL-20984-02 0005 Cellular mechanisms in cardiac
hypertrophy ■ Neurohumoral receptors in cardiac growth
and compensatory hypertrophy (animals)
R01HL-2U40-01 Studies of pulmonay alveolar
macrophage function (rabbits)
ROlHL-21482-01 Cardiac function and metabolism in
diabetes (rats)
R23HL-2184201 Control of sugar entry in normal and
diabetic heart (rats)
ROlHL-21970-01 Myofibrillar assembly and breakdown in
cardiac muscle (rats)
•• ROlHL-2205302 The disordered lipid metabolism of
diabetes mellitus (chickens, mammals, human)
ROlHL-2206402 Glycogen metabolism in anoxic diabetic
myocardium (rats)
ROlHL-22101-02 Hormone-substrate interaction in diabetic
myocyte (dogs, rats)
ROlHL-2212102 Dyslipoprotcinemia in diabetes and
vascular disease (human)
ROlHL-22123-02 The role of the red cell in diabetic
atherosclerosis (human)
ROlHL-22500-01 Conversion of choline to
phosphatidylcholine in lung (rabbits, pigs)
ROlHL-22581-02 Neurocirculatory control in diabetes
mellitus (human)
POlHL-2261901 0010 Cellular mechanisms of heart
failure - Mitochondria in heart and smooth muscle (rabbits,
rats, dogs)
ROlHL-2281201 Regulation of hepatic production of HDL
(rats)
NOlHV-12159-09 Lipid research clinic
PANCREAS HORMONES, INSULIN INHIBITORS
ROlHL-08506-15 Lipemia-carbohydrate and glyceride
metabolism (human, rats)
PANCREATIC CYSTIC FIBROSIS
SEE METABOLIC DISORDERS INBORN, CYSTIC FIBROSIS
PANCREATIC ENZYMES
SEE PANCREAS, PANCREATIC ENZYMES
PANCREATIC ISLETS DISORDERS
SEE ALSO CARBOHYDRATES METABOLISM DISORDERS
DIABETES
R01HL-2038103 Long-term study of diabetic vascular
disease (human)
PANCREATIC ISLETS DISORDERS,
HYPERINSULINISM
" POlHL-06835-17 0024 Cardiovascular disease - Studies
on the obese spontaneously hypertensive rat
ROlHL-08506-15 Lipemia-carbohydrate and glyceride
metabolism (human, rats)
PANCREATIC LIPASE
SEE LIPASES. TRIACYLGLYCEROL LIPASE
PANCREATIN
SEE PANCREAS, PANCREATIC ENZYMES
PANCREATITIS
SEE PANCREAS DISORDERS, PANCREATITIS
PANCREATOPEPTIDASE E
SEE PROTEASES AND PEPTIDASES, EUSTASE
PANCREOZYMIN
SEE GASTROINTESTINAL HORMONES, PANCREOZYMIN-
CHOLECYSTOKININ
PANCREOZYMIN-CHOLECYSTOKININ
SEE GASTROINTESTINAL HORMONES, PANCREOZYMIN-
CHOLECYSTOKININ
PANCURONIUM
SEE ANDROSTANE SERIES, PANCURONIUM
PAPAIN
SEE PROTEASES AND PEPTIDASES, PAPAIN
PAPAVERINE
SEE QUINOLINES, ISOQUINOLINES, PAPAVERINE
PAPAYA ENZYME
SEE PROTEASES AND PEPTIDASES, PAPAIN
PAPILLARY MUSCLES
SEE HEART, PAPILLARY MUSCLES
PAPIUEDEMA
SEE EYE DISORDERS. PAPILLEDEMA
396
PARABIOSIS, VASCULAR
SEE CARDIOVASCULAR SURGERY. EXTRACORPOREAL
CIRCULATION, CROSS CIRCUUTION
PARAGANGLIA
SEE NERVOUS SYSTEM, PARAGANGLIA
PARAGANGLION AORTICUM
SEE NERVOUS SYSTEM, PARAGANGLIA, AORTIC BODY
PARAGANGLION CAROTICUM
SEE NERVOUS SYSTEM, PARAGANGLIA, CAROTID BODY
PARAINFLUENZA VIRUSES
SEE VIRUSES. PARAMYXOVIRUSES. PARAINFLUENZA VIRUSES
PARALLEL PATH MODEL
SEE BIOLOGICAL TRANSPORT, MEMBRANE MODELS
PARALYSIS
SEE NEUROMOTOR DISORDERS, PARALYSIS
PARALYSIS AGITANS
SEE NEUROMOTOR DISORDERS, PARKINSONS DISEASE
PARALYSIS OF FOWL (MAREK'S)
SEE NERVOUS DISORDERS CENTRAL. MAREK'S DISEASE
PARAMEDICAL EDUCATION
SEE EDUCATION. HEALTH OCCUPATIONS, ALLIED
PARAMEDICAL PERSONNEL
SEE HEALTH SCIENCES PROFESSIONS, HEALTH (CARE)
PERSONNEL ALLIED
PARAMYOSIN
SEE MUSCLE PROTEINS (AND CONTRACTILE PROTEINS)
PARAMYOSIN
PARAPLEGIA
SEE NEUROMOTOR DISORDERS, PARALYSIS, PARAPLEGIA
PARAPROTEINEMIAS ACQUIRED
SEE BLOOD PROTEINS DISORDERS
PARAPROTEINEMIAS CONGENITAL
SEE BLOOD PROTEINS DISORDERS CONGENITAL
PARAQUAT
SEE PESTICIDES, HERBICIDES, PARAQUAT
PARASITIC DISEASES, HELMINTH INFECTIONS
(GENERAL)
SEE ALSO IMMUNOLOGY, ANTIGENS HELMINTHIC
" P01HL08805-15 0049 Regulation of ventilation and
pulmonary circulation - Pulmonary hypertension produced
by Dirofilaria immitis in the dog
PARASITIC DISEASES, HEUMINTH INFECTIONS,
SCHISTOSOMIASIS
ROlHL-19732-03 Lymphokines in pulmonary
granulomatous inflammation (mice)
PARASITIC DISEASES, PROTOZOAL INFECTIONS,
MALARIA
SEE ALSO COMMUNICABLE DISEASE CONTROL AGENTS
ANTIMALARIALS
POlHL-16833-04 0014 Hemoglobin and red cell system in
hemoglobinopathies - Erythrocyte membrane damage in Hb
SS disease (human)
PARASYMPATHETIC NERVOUS SYSTEM
SEE NERVOUS SYSTEM AUTONOMIC, PARASYMPATHETIC
NERVOUS SYSTEM
PARASYMPATHOLYTIC AGENTS
SEE NEUROPHARMACOLOGICAL AGENTS,
PARASYMPATHOLYTIC
PARASYMPATHOMIMETIC AGENTS
SEE NEUROPHARMACOLOGICAL AGENTS,
PARASYMPATHOMIMETIC
PARATERMINAL BODY (SEPTAL AREA)
SEE BRAIN. LIMBIC SYSTEM. SEPTAL AREA
PARATHIAZINE
SEE THIAZINES
PARATHYROID GLANDS DISORDERS,
HYPERPARATHYROIDISM
R01HL-14720-08 Factors governing the renal excretion of
acid (humans, rats)
PARATHYROID HORMONES
R01HL-00340-29 Electrolyte disturbance in cardio-renal
disease (human, dogs, rats)
ROlHL-14133-08 Intrarenal regulation of sodium
reabsorption (dogs, hamsters, rats)
P01HL-14388-07 0191 Regulation of the circulation in
pathological states - Regulation of chloride transport in
epithelial membranes (turtles)
** ROlHL-14720-08 Factors governing the renal excretion of
acid (humans, rats)
R01HL-16658-05 Intrarenal regulation of sodium
reabsorption
R01HL-19961-03 Management of hemosiderosis in
thalassemia (children, adults)
PAT
R01HL-22561-01 Hormonal control of mesenteric
circulation (cats)
PARATHYROIDECTOMY
ROlHL-14720-08 Factors governing the renal excretion of
acid (humans, rats)
PARENT-CHILD
SEE FAMILY, PARENT-OFFSPRING
PARENT-OFFSPRING
SEE FAMILY, PARENT-OFFSPRING
PARENTERAL FEEDING
SEE NUTRITION, Oin SCHEDULE AND ROUTE. PARENTERAL
FEEDING
PARENTS
SEE FAMILY, PARENTS
PARIETAL LOBE
SEE BRAIN, CEREBRUM, PARIETAL LOBE
PARKINSON'S DISEASE
SEE NEUROMOTOR DISORDERS, PARKINSONS DISEASE
PAROXYSMAL NOCTURNAL HEMOGLOBINURIA
SEE HEMOPROTEINS, HEMOGLOBINURIA, PAROXYSMAL
NOCTURNAL
PARTICLE ACCELERATORS
SEE RADIATION. PARTICLE ACCELERATORS
PARTICLE BEAMS SUPRAMOLECULAR
SEE PHYSICAL PROPERTIES. AEROSOL AND PARTICLE BEAMS
PARTICLE COUNTERS
R01HL-20024-03 Therapeutic aerosols -Characteristics and
retention (human, dogs)
POlHL-22163-01 0002 Surface thrombogenesis -
Mechanisms and prevention - Laser-scattering detection of
microemboli in blood flow (baboons)
PARTICLES AND PARTICULATE MATTER
SEE PHYSICAL PROPERTIES. PARTICLES
PASSIVE CUTANEOUS ANAPHYLAXIS
SEE HYPERSENSITIVITY. SKIN SENSITIZING ANTIBODY
PASSIVE IMMUNIZATION
SEE IMMUNITY. IMMUNIZATION PASSIVE
PASSIVE SENSITIZATION
SEE HYPERSENSITIVITY, SENSITIZATION PASSIVE
PASSIVE SENSITIZATION TRANSFER FACTOR
SEE HYPERSENSITIVITY, TRANSFER FACTOR
(HYPERSENSITIVITY)
PASSIVE TRANSPORT
SEE BIOLOGICAL TRANSPORT. PASSIVE TRANSPORT
PATELLA
SEE SKELETAL SYSTEM. JOINT. KNEE
PATENT DUCTUS ARTERIOSUS
SEE CONGENITAL ABNORMALITIES. CARDIOVASCULAR SHUNTS
ABNORMAL, PATENT DUCTUS
PATHOBIOLOGICAL CHEMISTRY STUDY SECTION
ROlHL-15125-07 Molecular pathology of genetic disorders
in man
ROlHL-16588-05 Collagen synthesis in atherosclerosis
(dogs, rats, rabbits, human)
R01HL-16904-03 Regulation of smooth muscle cells in
arteriosclerosis (rabbit aorta)
** R01HL-17995-04 Cellular synthesis and release of
mucopolysaccharides (rabbits)
ROlHL-18561-03 Radioimmunoassay of angiotensinogen
Angiotensin converting enzyme of human
I^"^.™"*'"! ""*'"x'''K>» OR "vefs only general projects which preclude indexing at the specific level
"Oriented significantly to above subject.
M Grant has subprojeds describing specific research aspects.
See Appendix for investigator's name and grant number.
(human)
ROlHL-18908-03
serum
ROlHL-18918-03 Characterization of lung elastins (rat,
rabbit, chicken. Rhesus)
ROlHL-18931-02 Lung elastic tissue characteristics
(swine, human)
R01HL-19011-03 Smooth muscle cell membrane
glycoprotein biosynthesis (cattle)
ROlHL-19252-02 Vascular connective tissue-Role in
atherosclerosis (rabbits)
R01HL-19820-02 The chemistry and biological effects of
heparin (Rhesus, human, other mammals)
ROlHL-20546-02 Chemical analysis of human arterial
elastin
ROlHL-20547-02 Glycoproteins in pulmonary alveolar
proteinosis (human)
ROlHL-20764-02 Elastin and calcification in pulmonary
and vascular disease (human, mammals)
ROlHL-20868-02 Regulation of glycoprotein biosynthesis in
lung (swine)
ROlHL-21095-02 Enzymes of M tuberculosis and
obstructive lung disease (human, rodents)
R23HL-21225-02 Connective tissue precursor molecules in
the lung (rabbits, hamsters)
ROlHL-21303-02 Collagen synthesis by cultured human
vascular cells
R23HL-21328-02 The I blood group antigen of human
erythrocyte membrane
(contd)
PAT
" R23HL2U1102 Control ot e>t(acellular lysosomal
hydrolase Itvels (rats)
*• R23HL 21413 02 Strudura and function o( pidtelet
calcium binding protein (human)
*• ROIHL 21480 01 Structure, source and lunctions ol
alveolar glycopioteins (human, rabbits)
•* R23HI 21488 01 Myosin linKed regulation in vertebrate
smooth muscle (calt aorta)
** R23HL 21504 02 Collagen synthesis in pulmonary fibrosis
cells (human)
•* ROIHL 21615-01 Structural studies ol lung heparinoid
polysaccharides (cattle)
*• ROIHL 2164401 Fibronectin and related glycoproteins
(human, rodents)
** R23HL 21663 01 Regulation ot collagen biosynthesis
(chick, embryo)
•* R01HL2166501 Collagen polymorphism and arterial
structure (monkeys, guinea pigs)
** ROIHL 21763 09 Heparin and heparan sulfate- Structure
and activity (beet, hog)
•* ROIHL 22242 01 The converting enzyme ol lung (cattle.
human)
*• R01HL22401-01
the heart
" ROlHL-22651-01
muscle
•* ROIHL 22729-01 Intracellular degradation ot newly
synthesized collagen (human, chick, rabbit)
** R23HL-22818-01 Biosynthesis of human respiratory
mucous glycoprotein (also dog)
** ROIHL 23587-01 Phosphorylation of myocardial protein
(guinea pigs)
** ROlHL-23994-01 Biochemical properties of human cardiac
myosin
PATHOGENIC DIET
SEE NUTRITION, DIET PATHOGENIC
PATHOLOGIC PROCESSES
SEE DISEASES, PATHOLOGIC PROCESSES (NOT CLASSIFIED
ELSEWHERE)
PATHOLOGY
SEE DISEASES, PATHOLOGY (GENERAL)*
PATHOLOGY MICROSCOPIC
SEE HISTOPATHOLOGY (GENERAL)*
PATHOLOGY STUDY SECTION
** ROlHL-01623-24 Antigens related to graft rejection
Regulation of tension and active state in
Control of protein metabolism in heart
Arteriosclerosis, glomerulonephritis.
(rabbits, rats)
ROlHL-01803-23
rheumatic fever
ROlHL-01979-22 Arteriosclerosis in zoo animals on
controlled diets (animals)
R01HL-02986-21 Zonal renal change with potassium
deficiency (rats, human)
R01HL-04300-20 Fine structure of diseased glomeruli
(human, rats, dogs)
ROlHL-05694-20 Functional pathology of cardiovascular
disease (human)
ROlHL-07835-17 Experimental hypertension and renal
circulation (rats, rabbits)
ROlHL-09622-14 Pathogenesis of atherosclerosis (rats)
ROlHL-10980-11 Ultrastructural renal pathology (human,
rats)
ROlHL-1 1897-11 Pathogenesis of experimental
atherosclerosis (rabbits, guinea pigs)
ROlHL-11963-10 Biochemistry of blood vessel formation
and disease (swine)
ROlHL-1255709 Effects of steroids and pregnancy on
arteries and veins (guinea pigs)
R01HL12561-11 Cardiovascular studies on copper
deficiency (swine)
ROlHL-12650-08 Environmental pathobiology of the lung
(hamsters, rats)
' ROlHL-13632-08 Vascular changes in diabetes mellitus
(human)
' ROlHL-13594-08 Capillary basement membrane in
cardiovascular disease (human, rats)
' ROlHL-1372208 Acid and alkaline lipases in aortas (rats,
rabbits, human)
' ROlHL-13901-08 Ontogeny, ultrastructure, function in
lymphatic system (birds, fish, mammals)
' R01HL-I4262-07 Leukocyte proteases and their lung
targets (human, dogs, rabbits)
* ROlHL-14700-05 Humoral and lung protease-antiprotease
role in obstructive disease (human)
* ROlHL-1484406 Mucous glycoprotein in human respiratory
epithelium (also wheat)
' ROlHL-15797-05 Lipid metabolism and atherosclerosis in
primates (monkeys, human, squirrels)
* ROlHL-15965-06 Experimental atherosclerosis and elastin
metabolism (chicks)
* R01HL-I6714-05 Endothelial cell communication in
homeostasis (human, mammals)
* ROlHL-16952-05 Cardiovascular pathology (rats, rabbits)
I ROlHL-17543-03 Magnetic tracers for diagnosis of lung
disease
* ROlHL-17596-03
* ROlHL-17747-04
* ROlHL-17973-04
Leukocyte-endothelial interactions (rats)
Endothelial injury and regeneration (rats)
Cultured aortic endothelial cells (human.
397
ROIHL 18085 03 Ncur.il factors in .ilherogoncsis (squirrel
monkeys)
ROIHI 18152 03 Vascular injury and atherosclerosis
(mice, coxsackievirus)
ROIHI 1815/04 Subcellular events in atherosclerosis
(human, rabbits, calves)
ROIHL 18340 04 Election microscopy of the
juxtaglomerular apparatus (rats)
ROIHI 18473 04 Genesis of atherosclerotic lesions
(human, mules)
ROIHL 18631 03 Ultrastructural correlates of myocardial
ischemia (rats, swine)
ROIHL 18714 04 Cardiovascular matrix Morphogenesis
and maturation (human, chick embryo, mammal)
ROIHL 18824 03 Mechanisms of heart failure in
myopathic hamster
ROIHL 18826 04 Interaction of peptides and target cells
in lung (human)
ROIHL 18923 02 Steroid induced hyperlipidemia and
hypertension (human, rats)
ROIHL 18952-03 Metabolism in perfused fetal and
newborn rabbit lungs
' ROIHL 1900003 Irreversible myocardial injury (rats)
' ROlHL-19001 03 Atherosclerosis m bleeder and drug
treated subjects (pigs)
' ROlHL-19018-03 Etiologic factors in cryptogenic fibrosing
alveolitis (human)
' ROlHL-19053-03 Vascular anatomy of the telencephalon
(human)
' ROlHL-19072 03 Modification of tissue injury in
myocardial infarction (dogs, human)
' ROIHL 19077-01 Biochemistry and molecular biology of
sarcoidosis (human, rabbits)
' ROlHL-19109-03 Regression of chronic atherosclerosis
(rabbits)
' ROIHL 19237 03 Obstructive lung disease and alveolar
macrophages (human, animals)
* ROlHL-193 16-03 Study of glomerular permeability (fish,
turtle, frog, chordates. Crustacea)
* ROlHL-19378-03 Relation of mitochondrial changes to
cardiac failure (dogs, rats)
* ROlHL-19379-03 Characterization ot small-granule cells in
the lung (mammals)
* R01HL-1942903 Phagocytosis-lngestion in alveiolar
macrophages (rabbits)
* ROlHL-19539-03 Pathology of hypertensive-associated
arteritis (rabbits)
* ROlHL-19651-03 Host factors in pathogenesis of
respiratory disease (human, hamsters)
* ROlHL-20189-01 Effects of renin on atherogenesis
(rabbits)
* ROlHL-20197-02 Maintenance and repair of vascular
endothelium (human, animals)
* ROlHL-20199-02 Drug-induced alterations in infarct size
in the rat
* ROlHL-20400-03 Diabetic neuropathy and peripheral
vascular diseases (human, hamsters)
* ROlHL-20500-02 Diabetic human brain microvascular
basement membrane (human)
* ROlHL-20548-02 Innervation of the lung (rats, monkeys)
* ROlHL-20675-02 Alveolar macrophage function in man
■* ROlHL-20875-02 Chronic obstructive pulmonary disease-
Familial/genetic (human)
'* ROlHL-20878-02 Cellular aspects of lung injury (rats.
rabbits)
'* ROlHL-20963-01 Experimental lung abscess (rabbits)
'* R23HL-21 116-02 Mechanisms of membrane and tissue
damage in lung (dogs, rabbits)
'* ROlHL-21120-02 Membrane dynamics in alveolar
macrophages (rabbits)
'* ROlHL-21 126-02 Exercise-induced bronchospasm in
children
" R23HL-2 11 34-02 Immune function and fibrogenesis in
silicosis (guinea pigs)
** ROIHL-21 156-02 Antitrypsin and other causes of chronic
lung disease
** R23HL-21327-02 Molecular mechanisms of chemical
myocardiopathies (rats)
** R23HL-21369-02 Tracheal mucin synthesis in experimental
bronchitis (rats)
** R23HL-21396-02 Isolation, growth and metabolism of type
1 pneumocytes (rabbits)
** ROlHL-21416-02 Atherosclerosis in new modles of
diabetes mellitus
** ROlHL-2142902 Transport of LDL in arterial wall (human,
mammals)
•* ROlHL-21438-02 Structure and permeability of arterial
endothelium (pigs)
** ROlHL-21548-01 Pathogenesis of pulmonary
thromboembolic disease (human, mammals)
** ROlHL-21565-02 Pathogenesis of inflammatory lung injury
(rats, rabbits)
** R01HL-21592-01 Lipoproteins and coagulation factors in
atherosclerosis (pigeons)
** ROlHL-21829-01 Etiology of obstructive airway disease in
children (also monkeys)
** R23HL-21918-01
pigs
** R23HL-21943-01
Hypersensitivity pneumonitis in guinea
Capillary morphology in pulmonary
edema (dogs)
ROlHL-21948-01
" R23Ht 2195001 (ndothdul cell mechannmj in vi»culi(
disease (human)
•* ROIHL 21994 01 Structure and development ol
regenerating capillaries (rabbits, chitk embryo)
•• R23HI 2199/01 Pulmonary immunopathology in the
compromised host (guinea pig'.)
*• ROIHI 2214901 Morphologic examination of brain
parenchymal vessels (cats)
** ROIHI 22302 01 Immune responses in the human lung
(also rabbits, monkeys)
•• ROIHL 22341 01 Pathogenesis of atherosclerosis in rats
■• R23HI 2243/01 Leukotactic mediators in lung
inflammatory reactions (rats, rabbits, human)
*' ROIHL 22444 01 Bronchial mucus production in organ
culture (human)
•* ROIHL 22520 01 Pulmonary vascular response to group B
Streptococci (human, mammals)
" ROIHL 22552 02 Abnormal alveolar permeability and lung
disease (sheep)
** ROIHL 22583 02 Ultrastructural study of endothelium in
thrombosis (human)
** ROIHL 22676 01 Pathogenesis in experimental interstitial
pneumonitis (rabbits)
•* ROIHL 22739-01 Evolution and progression of pediatric
atherosclerosis
** ROIHL 22883 01 Lung epithelial cell interactions in vitro
** R23HL 22895-01 Smoke inhalation Biochemical and
cellular responses (rabbits, bacteria)
** R01HL2359501 Experimental emphysema- Depression of
protease inhibitors (rats, hamsters)
** ROIHL 23603 01 Morphogenesis of hypertensive vascular
disease (rats)
** ROlHL-23981 01 Acute alveolar injury (dogs)
PATIENT CARE
SEE HEALTH CARE SERVICES, PATIENT CARE
PATIENT CARE, CANCER PATIENTS
SEE HEALTH CARE SERVICES, CASE FINDING AND OUTREACH
PATIENT CARE, COMPREHENSIVE
SEE HEALTH CARE SERVICES, PATIENT CARE MANAGEMENT,
COMPREHENSIVE CARE
PATIENT CARE, HOME CARE
SEE HEALTH CARE SERVICES. HOME CARE
PATIENT CARE MANAGEMENT
SEE HEALTH CARE SERVICES. PATIENT CARE MANAGEMENT
PATIENT CARE PLANNING
SEE HEALTH CARE SERVICES, PATIENT CARE MANAGEMENT,
PUNNING
PATIENT CARE QUALITY
SEE HEALTH CARE QUALITY
PATIENT MONITORING (AUTOMATED)
SEE BIOMEDICAL SYSTEMS AUTOMATED. PATIENT
MONITORING (MONITORING DEVICES)
PATIENT PROFESSIONAL RELATIONS
SEE HEALTH CARE SERVICES, PATIENT-PROFESSIONAL
RELATIONS
PATIENT REFERRAL
SEE HEALTH CARE SERVICES, REFERRAL AND CONSULTATION
PATIENT REGISTRIES
SEE HEALTH RECORD SYSTEMS, PATIENT (DISEASE)
REGISTRIES
PATTERN RECOGNITION (COMPUTER)
SEE COMPUTER, ARTIFICIAL INTELLIGENCE, PAHERN
RECOGNITION AND CONTROL SYSTEMS
PATTERN RECOGNITION, COMPUTER (OTHER
THAN IMAGE-WAVESHAPE, OR COMPUTER
SIMULATION OR DIAGNOSIS)
SEE COMPUTER, ARTIFICIAL INTELLIGENCE, PATTERN
RECOGNITION AND CONTROL SYSTEMS
PBB
SEE HALOBENZENES, HALOGENATED BIPHENYLS-TRIPHENYLS
AND ANALOGS
SEE HALOPROTEINS, PROTEIN BOUND IODINE
r
SEE HALOBENZENES, HALOGENATED BIPHENYLS-TRIPHENYLS
AND ANALOGS
SEE HALOBENZENES, HALOGENATED BIPHENYLS-TRIPHENYLS
AND ANALOGS
PCPA (PARACHIOROPHENYLALANINE)
SEE CYCLIC AMINO ACIDS, PHENYULANINE, P-
CHLOROPHENYLALANINE
PBI
PBT
PCB
PCT
SEE HALOBENZENES, HALOGENATED BIPHENYLS-TRIPHENYLS
AND ANALOGS
Capillary, tissue volume and lymph flow
cattle, dogs, swine)
in lung edema (sheep, cattle)
PEDIATRIC CARE (SERVICES)
SEE CHILD HEALTH CARE (SERVICES)
(contd)
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subptojects describing specific research aspects.
See Appendix for investigator's name and grant number
PEL
PEER GROUPS
SEE PSYCHOLOGY SOCIAL, GROUP PROCESSES, PEER
GROUPS
PELLAGRA PREVENTIVE FACTOR
SEE PYRIDINE CARBOXYLIC ACIDS, NICOTIMC ACID
PENICILLAMINE
SEE SULFUR AMINO ACIDS, PENICILUMINE
PENICILLIN
SEE ANTIBIOTICS, PENICILLIN
PENICILLIN G
SEE ANTIBIOTICS, PENICILLIN G
PENTOBARBITAL
SEE PYRIMIDINES, BARBITURATES, PENTOBARBITAL
PENTOSE PATHWAYS
R01HL1771903 Lung injury, substrate utilization, oxygen
toxicity (fats, rabbits, dogs)
PENTOSE PATHWAYS, HEXOSE
MONOPHOSPHATE PATHWAY
ROlHL-1294409 Enzymatic and biochemical studies on
blood cells (human)
P60HL-15999-05 0008 Miami comprehensive sickle cell
center - Cyanate effect on host defense-Cellular and
humoral (human, guinea pig, rabbits)
R01HL19324-02 Mechanisms of the inhibition of sickling
by DBA (human)
R01HL1962803 Mechanisms of pulmonary alveolar
proteinoses (human, rats)
R01HL-20I25-02 Cyclic nucleotides and alveolar
macrophage activation (rabbits)
ROlHL-2255501 Structure and function of platelet
activating factor (rabbits, human)
PENTOSES, XYLOSE
RClHL-21641-02 Structural studies of lung proteoglycans
(pigs, cattle, rabbits)
PEPTIC ULCER
SEE GASTROINTESTINAL DISORDERS. PEPTIC ULCER
PEPTIDASE INHIBITORS
SEE ENZYME INHIBITORS, PROTEASE INHIBITORS (GENERAL)
PEPTIDASES
SEE PROTEASES AND PEPTIDASES, PEPTIDASES
PEPTIDE STRUCTURE
SEE PROTEINS-PEPTIDES STRUCTURE
PEPTIDE-POLYPEPTIDE HORMONES
BIOSYNTHESIS
SEE ENDOCRINOLOGY, HORMONES BIOSYNTHESIS, PEPTIDE-
POLYPEPTIDE HORMONES BIOSYNTHESIS
PEPTIDE-POLYPEPTIDE HORMONES
SEE ENDOCRINOLOGY, HORMONES. PEPTIDE-POLYPEPTIDE
HORMONES
PEPTIDE-POLYPEPTIDE RELEASING FACTORS
SEE PITUITARY-DIENCEPHALON HORMONES, LH RELEASING
FACTOR
PEPTIDES
SEE ALSO AMINO ACIDS, N-CARBAMYL AMINO ACIDS
SEE ALSO ENDOCRINOLOGY, HORMONES, PEPTIDE-
POLYPEPTIDE HORMONES
SEE ALSO GLYCOPEPTIDES
SEE ALSO PROTEASES AND PEPTIDASES
** PCIHL 11310-12 0062 Mechanisms of cardiovascular
disease - Myocardial depressant factor in postoperative
cardiac dysfunction (human, dogs)
P50HL-14236-05 0003 Prevention of premature
arteriosclerosis - Intravascular clotting in patients with
hyperlipidemia
R01HL15308-07 Assays for peptides of lipoproteins
(human)
" P01HL15486-06 0001 Studies on thrombosis - Studies on
chemistry of fibrinogen (human, dogs)
" P01HL-15486-06 0002 Studies on thrombosis -
Characterization of antisera to fibrinopeptide B (human,
rabbits)
" P01HL-15486-06 0003 Studies on thrombosis -
Mechanism and prevention of fibrinopeptide B degradation
(human)
** P01HL-15486-06 0004 Studies on thrombosis -
Thrombosis, intravascuair coagulation, platelet aggregation
(dogs)
** POlHL-15486-06 0006 Studies on thrombosis - Clinical
investigation unit
POlHL-16607-05 0005 Calcium ion and control of
cardiovascular (unction ■ Chemical modifications of the
sarcoplasmic reticulum membranes (rabbits)
P0IHL17382-05 0003 Chemical mediators of acute
pulmonary disorders - Chemical mediators relevant to
allergic reactions (human, guinea pigs)
** ROIHL- 17896-03 Dehydropeptide renin substrates
ROlHL-18259-03 Controlled intratissue release of
prostaglandins
398
POlHL-18827-02 0002 Platelet vessel wall interactions in
thrombogenesis - Interactions of vessel wall
macromolecules with factor XII (human, rats)
ROlHL-19517-03 Synthesis of inhibitors for the study of
renal renin (dogs, monkeys)
ROlHL-19538-03 Synthesis of potential antihypertensive
agents
** ROlHL-19977-02 Genesis of circulatory shock by
pancreatic peptides (cats, dogs)
POlHL-20994-02 0009 Dynamics of neutrophil elastase in
the lung - Biosynthesis and degradation of elastin in
emphysema (human, hamsters)
P50HL-21006 02 0006 Specialized center of research in
arteriosclerosis - Intravascular coagulation and thrombosis
in hyperlipidemia (human)
ROlHL-22607-01 Role of apolipoprotein E in lipoprotein
metabolism (human)
POlHL-226 19-01 0001 Cellular mechanisms of heart
failure - Cell membrane isolation and reconstitution (dogs,
lambs)
POlHL-22633-01 0004 Cellular and molecular biology of
lipoprotein metabolism - Lipid-lipid and lipid-protein
interactions in serum lipoproteins (human, rats)
ROlHL-22780-01 Factors modifying the reaction properties
of HgS (human)
NOlHV-42984-05 Interactions of modified biopolyniers with
blood (humans, rats)
PEPTIDES, GLUTATHIONE
POlHL-06370-17 0015 Cardiopulmonary and renal
pathology research center - Pathogenesis of chemically
Induced tissue injury (rats)
POlHL-12157-11 0051 Functions and mechanisms of cell
membrane ion transport - Electron transport in the red cell
membrane (human, guinea pigs)
ROlHL-12944-09 Enzymatic and biochemical studies on
blood cells (human)
** ROIHL- 129 72-09 Glutathione deficiency in red cells
(sheep, dogs)
POlHL-16851-04 0006 Human red cell membrane in
health and disease - Hexose transport and erythrocyte
membrane proteins (human)
ROlHL-17719-03 Lung injury, substrate utilization, oxygen
toxicity (rats, rabbits, dogs)
PEPTIDES, HOMOPEPTIDES
** ROlHL-23183-01 Voltage dependent conductance in
membranes
PEPTIDES, HOMOPEPTIDES, GLUTAMYL
POlHL-15195-04 0003 Program project in biological
materials - Mechanical evaluation and fabrication
PEPTIDES, HOMOPEPTIDES, LYSINE PEPTIDES
ROlHL-17525-03 Molecular basis of collagen-platelet
interaction (human, rat)
PEPTIDES, OLIGOPEPTIDES
R01HL01662-25 Equilibria in the fibrinogen-fibrin
conversion (human, cattle)
ROlHL-1 1822-10 Biophysical studies of macromolecular
interactions (microorganism, human)
ROlHL-13909-27 Physiochemistry and immunology of
macromolecules
POlHL-16769-05 0002 Pathobiologic and host defense
reactions in the lung - Pathogenesis of complement
dependent injury to the lungs (rabbits)
ROlHL-188 18-04 Stereochemical mechanism of sickling of
hemoglobin S (human)
ROlHL-19795-03 Synthesis of anaphylatoxic and
leucotactic peptides (human)
ROlHL-21543-02 Structure-function relation of blood
clotting proteins (rabbits)
ROlHL-21544-02 Proteins of coagulation and Hageman
factor pathways (human, goats)
PEPTIDES, OLIGOPEPTIDES, SARALASIN
POlHL-03174-23 0001 Mechanisms of acute vascular
reaction to injury - Response of the vascular infima to
injury (human, rats)
** POlHL-06835-17 0030 Cardiovascular disease - Synthesis
and pharmacology of angiotensin antagonists (rats, cats)
** POlHL-06835-17 0038 Cardiovascular disease - Effect of
chronic administration of angiotensin antagonist (rats)
** POlHL-06835-17 0055 Cardiovascular disease - Vascular
and adrenocortical response to angiotensin II (dogs)
POlHL-11678-11 0040 Cardiovascular dynamics and their
control - Control of plasma potassium concentration (dogs)
POlHL-11678-11 0064 Cardiovascular dynamics and their
control - Renal medulla -Control of renal hemodynamics.
electrolyte excretion (dogs)
** ROlHL-13595-08 Renin and vascular hyper-reactivity in
hypertension (human, rats)
P50HL-141 92-08 0005 Specialized center of research in
hypertension - New techniques for recognition of
renovascular hypertension (human, dogs)
ROlHL-14944-07 Renal vascular reactivity in hypertensive
patient
ROlHL-15580-06 Humoral control of pulmonary and
systemic circulation (animals)
ROlHL-17403-03 Metabolic control of cardiac output
(dogs)
PEP
POlHL-17871-04 0009 Kidney, sodium, cardiac output,
arterioles and hypertension - Kidney, sodium, cardiac
output, arterioles and hypertension
P50HL-18318-03 0010 Pathogenesis and complications of
hypertension - Hemodynamics in mineralocorticoid and low
renin hypertension (human)
P50HL-18318-03 0019 Pathogenesis and complications of
hypertension - Renin-angiotensin system in blood pressure
regulation (human, rat, dog)
P50HL-18323-04 0044 SCOR hypertension center -
Angiotensin blockade to identify angiotensin II factor in
hypertension (human)
ROlHL-18862-02 Thirst and its contribution to edema
(dogs)
ROlHL-19279-03 Intracellular action of aldosterone in
hypertension (human, rats)
ROlHL-19428-03 Role of angiotensin sensitivity in renin
release (human)
ROIHL- 19825-02 Renin-volume interactions in coarctation
hypertension (dogs)
ROlHL-21092-02 Factors other than renin in renal
hypertension (rats)
ROlHL-22051-01 Role of angiotensin II in vasopressin
release (human)
ROlHL-22216 02 Vascular mechanisms in renal
hypertension (dogs)
ROlHL-22411-01 Neuroendocrine involvement in
hypertension (rats)
R23HL-22438-01 The etiology of genetic hypertension
(rats)
R01HL22563-02 Prostaglandins, the kidney and
hypertension (rats)
ROlHL-22836-01 The spontaneously hypertensive kidney
(rats)
ROlHL-23602-01 Physiology of renin, aldosterone and
prostaglandin (human, rats, dogs)
PEPTIDES, POLYPEPTIDES
ROlHL-02477-23 Biosynthesis and function of lipids
(microorganisms, rats)
POlHL-06285-18 0215 Cardiovascular-respiratory
physiology and biochemistry - Conformation of biopolymers
** ROlHL-09283-14 Pharmacology of molluscan hearts (also
rabbits)
ROlHL-10316-13 Structural studies on low density serum
lipoproteins (human)
POlHL-11414-11 0033 Thrombosis and atherosclerosis
program - Human coumarin-induced prothrombin
ROlHL-11822-10 Biophysical studies of macromolecular
interactions (microorganism, human)
R01HL12684-09 Angiotensin I and converting enzyme In
hypertension (human, primates, dogs)
P50HL-14217-08 0048 Specialized center of research In
thrombosis - Fibrinolysis section -Structural studies (human,
animal)
P50HL-14236-05 0004 Prevention of premature
arteriosclerosis - Plasma lipoproteins (human, rats)
P50HL-14237-07 0003 Support for arteriosclerosis center
- Structure of lipoproteins and apollpoproteins (human,
rabbits)
P50HL-15062-07 0013 Study of lipoproteins, artery wall,
and atherosclerosis - Radioimmunoassay of apollpoproteins
(human, monkeys)
P60HL-15170-05 0017 Support for center for sickle cell
anemia - Control of hemoglobulin synthesis (human)
POlHL-15195-04 0001 Program project in biological
materials - Design and synthesis
POlHL-15195-04 0002 Program project in biological
materials - Structural and surface characterization
ROlHL-15690-07 Hydrolytic enzymes of blood in health
and disease (human, animals)
ROIHL- 1599 1-05 Evaluation of heart stimulants in sea
anemones
ROlHL-16445-05 Regulation of plasma protein
biosynthesis (rats, rabbits)
ROlHL-18015-03 Pharmacologic studies on vascular
smooth muscle (dogs, rats)
ROlHL-18245-03 Transition state analog inhibitors of
thrombin (human, cattle)
ROlHL-18526-03 Kinins and the human lung
P01HL-I8577-03 0003 Lipoproteins-Cell surface
interactions - Mechanism of lipid exchange in lipoproteins
and cell membranes
POlHL-18577-03 0004 Lipoproteins-Cell surface
interactions - Analysis and chemical modification of
proteins in lipid transport (human, dogs)
POlHL-18577-03 0005 Lipoproteins-Cell surface
interactions - Chemical synthesis of apollpoproteins and
apoliprotein fragments
POlHL-18577-03 0008 Lipoproteins-Cell surface
interactions - Core laboratory 1
POlHL-18577-03 0011 Lipoproteins-Cell surface
interactions - Core laboratory 4
ROlHL-19379-03 Characterization of small-granule cells in
the lung (mammals)
R23HL-19594-01 Tropocollagen and tropoelastin uptake in
lung cells (human)
POlHL-20592-02 0011 Cell biology of cardiac and
skeletal muscle - Myosin and cytochrome oxidase
messenger RNAs (chicken)
ROlHL-2109602 Sickle cell crisis -Role of the erythrocyte
membrane (human)
•Excludes rautlne methodotogy OR covers only general projects which preclude indexing at the specific level
Onented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
(contd)
Pfp
ROIHl 2112002 Mambran* dynamics in alveolar
macmphagas (rabbits)
ROIHL 21342 02 Isolation and analysis o( sodium channel
tiom bead ((togs)
NOIHI 21394 02 Pulmonary angiotansin-converting enzyme
(rabbits)
R01Hl'2184S'01 Human led cell membrane Structure and
(unction
ROIHL 22S7001 Interactions ol sterols in biological
systems (human)
** ROIHL'22618'01 Role ol apolipoproteins in
hyperttigtyceridemia (human)
** NOIHR'72923'01 Cystic librosis factor identification and
quantification (human)
PEPTIDES, UNNATURAL PEPTIDES
SEE ALSO PEPTIDES. HOMOPEPTIDES
ROIHL 1752S03 Molecular basis of collagen-platelet
interaction (human, rat)
ROIHL'18226'04 Mechanism of oxygen supply to tissue
(human, animals)
ROIHI 1881804 Stereochemical mechanism of sickling of
hemoglobin S (human)
ROIHL'19795'03 Synthesis of anaphylatoxic and
leucotactic peptides (human)
** ROIHL'23183'OI Voltage dependent conductance in
membranes
PEPTIDES, VASOACTIVE PEPTIDES
SEE ALSO PEPTIDES. OLIGOPEPTIDES, SARAUSIN
SEE ALSO PROTEASES AND PEPTIDASES. ANGIOTENSINASE
SEE ALSO PROTEASES AND PEPTIDASES.
PROLYLCARBOXYPEPTIDASE
R01HL-0555619 Proteins. Iipoproteins-Structure and
reactivity (chicken, human, diving mammals)
R01HL-10384'13 Blood flow and nucleotide metabolism
(animals)
ROIHL 1180210 Cardiovascular surgical research (dogs.
sheep, swine, cats, monkeys)
ROlHL-12677-10 Surgical physiologic studies of isolated
kidneys (dogs, rats)
** POlHL-1326207 0018 Arterial wall in atherosclerosis
Vasoactive factors of human plasma
M P50HL14187-07 Pulmonary SCOR-Chemical mediators in
pulmonary vascular responses
** P5OHL-14187-07 0012 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses - Vasoactive
mediators in pulmonary disease (human, animal)
** P50HL14187-07 0014 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses - Metabolism
and actions of vasoactive peptides in lung (human,
mammals)
** R01HL16320-05 Vasoactive peptides which stimulate
smooth muscles (rats, human)
POlHL-164 11-04 0001 Blood systems in coagulation and
vessel disease ■ Molecular studies of the role of
complement in blood coagulation (human, rabbits)
ROlHL-1708005 Localization of pore systems in capillary
walls (rats. mice, rabbits)
P50HL-17648-D4 0023 Study of ischemic heart disease •
Chemical mediators of inflammation in acute myocardial
infarction (mammals)
•* ROIHL- 17 705-04 Kallikrein-kinin system in hypertension
(human, rats, dogs)
** ROlHL-1802703 New vasoactive factors and their role in
hypertension (human, dogs, rats)
** ROlHL-18826-04 Interaction of peptides and target cells
in lung (human)
ROlHL-19374-03 Pharmacology of kinins in cardiovascular
disease (rats, rabbits)
** ROlHL-19539-03 Pathology of hypertensive-associated
arteritis (rabbits)
** R01HL-19795-03 Synthesis of anaphylatoxic and
leucotactic peptides (human)
** R01HL-2O22O-03 Anaphylatoxins as inflammatory and
chemotactic agents (guinea pig. rabbit, human)
** ROlHL-21394-02 Pulmonary angiotensin-converting enzyme
(rabbits)
ROlHL-21568-02 Cell biology of the alveolar-capillary unit
(animals)
** ROlHL-22244-01 Cardiopulmonary bypass and the
vascular endothelium (dogs)
** ROlHL-22288-01 Renin and precursors-Structure and
function (mice)
** R23HL-22346-01 Hematological injury and pulmonary
dysfunction (human, mammals)
*• ROlHL-23603-01 Morphogenesis of hypertensive vascular
disease (rats)
PEPTIDES, VASOACTIVE PEPTIDES,
ANGIOTENSIN
POlHL-06285-18 0146 Cardiovascular-respiratory
physiology and biochemistry - Pathogenesis and detection
of hypoxic pulmonary edema (human, animals)
** POlHL-06835-17 0030 Cardiovascular disease - Synthesis
and pharmacology of angiotensin antagonists (rats, cats)
POlHL-06835-17 0032 Cardiovascular disease - Synthesis
of angiotensin II as inhibitors for aldosterone
** POlHL-06835-17 0033 Cardiovascular disease - Structure-
activity relationship of angiotensin II analogs (rats)
POlKL-06835-17 0038 Cardiovascular disease - Effect of
chronic administration of angiotensin antagonist (rats)
39»
POIHI 06835 17 0056 Cardiovascular disease
Angiotensin analogs Sarcosine on irlariil pressure,
aldosterone (dogs)
POIHL 06835 17 0060 Cardiovascular disease
Ventricular performance experimental models of arterial
hypertension (rats, dogs)
POIHL 10342 13 0008 The integrated function of
respiration and circulation Respiratory mechanics and the
circulation (human, dogs)
POIHL 11678 11 0001 Cardiovascular dynamics and their
control Body fluid volumes in the genesis of hypertension
(rats, dogs)
POlHL-11678 11 0059 Cardiovascular dynamics and their
control Basic hemodynamics (dogs, rats)
POIHL 11678 11 0065 Cardiovascular dynamics and their
control Body fluid volumes in the genesis of hypertension
(dogs)
POIHL 11678 II 0068 Cardiovascular dynamics and their
control Basic hemodynamics (rats, dogs)
ROIHL 12684 09 Angiotensin I and converting enzyme in
hypertension (human, primates, dogs)
ROIHL 13408-05 Environmental-genetic interjctions in
hypertension (rats)
ROlHL-14148-07 0007 The regional circulations Salivary
compositron in hypertension (human)
P50HL-i4187-07 0014 Pulmonary SCOR -Chemrcal
mediators in pulmonary vascular responses Metabolism
and actions of vasoactive peptides in lung (human.
mammals)
P50HL 14217-08 0061 Specialized center of research in
thrombosis - Pharmacology-Comparison of platelets and
vascular smooth muscle (animal)
POIHL 14388-07 9002 Regulation of the circulation in
pathological states Core immunoassay laboratory (rabbits)
R01HL14397-07 Hypertension -Angiotensin and
prostaglandin pharmacology (animals)
ROlHL-14456-07 Lung metabolism-Enzymes in the
pulmonary circulation (human, animals)
ROlHL-1450907
of angiotensin
Hypertension -Chemistry and biophysics
Survival value of physiological responses
Renal vascular reactivity in hypertensive
R01HL1469307
to hypoxia (dogs)
ROlHL-14944-07
patient
ROlHL-15580'06 Humoral control of pulmonary and
systemic circulation (animals)
ROlHL-1575806 Catecholamine release in the heart
(dogs)
P01HL-I583206 0007 Chemical-structural predispositions
to lung injury - Inactivation of vasoactive agents by the
lung (human, rats. cats, dogs)
ROlHL-15837-06 Renin and cardiac hypertrophy in
hypertension (rats)
POlHL-1611705 0008 Ion movements and membranes In
cardiovascular control - Arterial smooth muscle calcium
fluxes and contractility (rabbits)
ROlHL-16320-05 Vasoactive peptides which stimulate
smooth muscles (rats, human)
ROlHL-16454-03 Vascular muscle reactivity in
hypertension (human, rats)
ROlHL-167 14-05 Endothelial cell communication in
homeostasis (human, mammals)
R01HL-I7366-05 Mechanisms in the production of renal
hypertension (rabbits, dogs)
ROlHL-17401-03 Mechanisms in angiotensin induced
hypertension (cats, dogs)
POIHL- 178 7 1-04 Kidney, sodium, cardiac output, arterioles
and hypertension
R01HL-I7896-03
R01HL18097-04
ROlHL-18259-03
prostaglandins
P50HL-1832304 0033 SCOR hypertension center - Core
laboratory-Renin. aldosterone and bradykinin methodology
POlHL-18575-03 0005 Mechanisms of vascular changes
in hypertension - Renin synthesis in normotensive and
hypertensive pigs (also rats, dogs)
ROlHL-187 18-04
reactivity (dogs)
ROlHL-1874903
heart (dogs)
ROlHL-18862-02
(dogs)
ROlHL-18875-03 Angiotension. prostaglandins, pressure
and the kidney (rats)
ROlHL-1903903 Circulation studies by one vs two circuit
model (dogs)
ROlHL-19057-03 Catecholamines and cyclic AMP in
cardiovascular system (rats, dogs)
ROlHL-19134-04 Angiotensin, prostaglandins, adrenergic
interactions (rats, rabbits)
POlHL-19242-02 0007 Study of vascular smooth muscle -
NE release in and reactivity of vascular smooth muscle
(animals)
POlHL-1924202 0008 Study of vascular smooth muscle -
NE release in and reactivity of vascular smooth muscle
(rats)
ROlHL-19287-03 The antihypertensive function of the
renal medulla (human, rats, rabbits)
' ROlHL-19320-03 Angiotensin neuropharmacology-
Relationship to sodium
Dehydropeptide renin substrates
Pathogenesis of acute renal failure (rats)
Controlled intratissue release of
Prostaglandin precursors and vascular
Ventricular mechanics in the overloaded
Thirst and its contribution to edema
PEP
ROIHL 19517 03 Synthetit of inhibitors for the ttudy of
renal renin (dogs, monkeys)
ROIHL 19538 03 Synthesis of potential antihypefltniivt
agents
ROIHL 19539 03 Pathology of hyperlintive aitociated
arteritis (rabbits)
ROIHL 19644 03 Etiological factors in hypertension
(human, dogs, rats)
ROIHL 1965303 Circulatory system effects of angiotensin
analogs (rats)
ROIHL 19675-02 Coronary pharmacoangiography
ROIHL 19997 02 Prostaglandin precursors and intestinal
vasculature (cats, rabbits)
ROIHL 20399 03 Vascular control in experimental diabetes
mellitus (dog)
ROIHL 20793 02 Phospholipids and cardiac receptor
function
POIHL 20984 02 0005 Cellular mechanisms in cardiac
hypertrophy Neurohumoral receptors in cardiac growth
and compensatory hypertrophy (animals)
ROIHL 21 112 02
secretion in man
R01HL2115602
lung disease
R01HL2127401
Aldosterone binding, clearance, and
Antitrypsin and other causes of chronic
Prorenm -Physiological and biochemical
analysis (human)
ROlHL-21394 02
(rabbrts)
ROlHL-21568-02
(animals)
ROlHL-21877-01
R23HL 21894-01
(cattle)
ROlHL-22172-01
Pulmonary angiotensin converting enzyme
Cell biology of the alveolar-capillary unit
Iso-renins in the hypertensive rat
Pulmonary angiotensin converting enzyme
Hypotension, renal ischemia and effect of
mannitol (dogs, rats)
ROlHL-22216-02 Vascular mechanisms in renal
hypertension (dogs)
ROlHL-22569-02 Intestinal secretion -Capillary and tissue
forces (dogs, cats)
ROlHL-2260301 Trace metals, vascular activity and
hypertension (rats)
** ROIHL 2289601 Immediate metabolic fates of kinins and
angiotensins (rat. rabbit, guinea pig)
PEPTIDES, VASOACTIVE PEPTIDES,
ANGIOTENSIN II
POlHL-03174-23 0001 Mechanisms of acute vascular
reaction to injury - Response of the vascular intima to
injury (human, rats)
P01HL03174-23 0005 Mechanisms of acute vascular
reaction to injury - Renal small vessel didease-Cell and
matrix response (human, mice)
ROlHL-05883-18 0001 Reflex control of resistance and
capacitance vessels - Naturally occurring vasoactive
substances and the vascular neuroeffectors (dog)
POlHL-0666417 0043 Cardiopulmonary function in
remediable vascular disease - Alveolar hypoxic
vasoconstriction -Control and clinical significance (dog.
human)
** POlHL-06835-17 0030 Cardiovascular disease - Synthesis
and pharmacology of angiotensin antagonists (rats, cats)
** POlHL-06835-17 0031 Cardiovascular disease - Synthesis
of potent antagonist of pressor action of angiotensin II
(animals)
** POlHL-06835-17 0032 Cardiovascular disease • Synthesis
of angiotensin II as inhibitors for aldosterone
** POlHL-06835-17 0033 Cardiovascular disease - Structure-
activity relationship of angiotensin II analogs (rats)
** POlHL-0683517 0039 Cardiovascular disease -
Reversibility of vascular changes in renal hypertension
(rats)
** P01HL0683517 0055 Cardiovascular disease - Vascular
and adrenocortical response to angiotensin II (dogs)
P01HL-0e835-17 0056 Cardiovascular disease -
Angiotensin analogs-Sarcosine on arterial pressure.
aldosterone (dogs)
ROlHL-08570-15 Pharmacologic and reflex influence on
vascular tone (dogs, rabbits)
ROlHL-09154-14 Central control of distribution of organ
blood flow (monkeys)
ROlHL-09921-13 Mechanisms related to congestive heart
failure (dogs, human, rat)
R01HL-I0182-13 Circulatory function and electrolytic
metabolism (dogs, human)
POlHL-10342-13 0024 The integrated function of
respiration and ciiculation - Cytochrome P450 and
physiological response to hypoxia (rats)
POlHL-10436-13 0014 A multidisciplinary study of
congenital heart disease - Cardiovascular pharmacology
(dog)
*• ROlHL-10612-13 0018 Humoral factors in heart failure
and hypertension - The pathogenesis of experimental renal
hypertension (dogs, rabbits, rats)
ROlHL-10612-13 0021 Humoral factors in heart failure
and hypertension ■ The control of aldosterone secretion
(dogs)
ROlHL-1091410 Renal sodium transport in experimental
aldosteronism (dogs)
POlHL-11678-11 0034 Cardiovascular dynamics and their
control Renal function curves in intact dogs
** POlHL-1 1678-11 0046 Cardiovascular dynamics and their
control - Regulation of aldosterone secretion and related
factors (dogs)
(contd)
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
PEP
POlHL-11678-11 0067 Cardiovascular dynamics and their
control - Angiotension II. sodium excretion and renal
hemodynamics (dogs)
POlHL-12738-10 0076 Physiologic pharmacology and its
clinical applications ■ Pediatric cardiac electrophysiology
and pharmacology (human, dogs)
ROlHL-12827-08 Regulation of sodium excretion (dogs
rats)
ROlHL-12990-09 Control of antidiuretic hormone secretion
and metabolism (dogs, rats, rabbits)
ROlHL-13315-08 Disposition of vasoactive hormones in
mammalian lung (rats, rabbits, human)
P50HL14147 08 0012 Specialized center of research in
thrombosis ■ Tissue culture study of arterial cells (human,
hamster)
P50HL-14187-07 0014 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses - Metabolism
and actions of vasoactive peptides in lung (human,
mammals)
P50HL-1419208 0005 Specialized center of research in
hypertension - New techniques for recognition of
renovascular hypertension (human, dogs)
P50HL-14218-07 0017 Pulmonary SCOR-Newborn lung
center - Transvascular fluid exchange, vasoactive mediators
in ROS (sheep, cat)
** POlHL-14388-07 0156 Regulation of the circulation in
pathological states Blood pressure with drinking to
intracranial angiotensin II injections (rats)
P01HL1438807 0178 Regulation of the circulation in
pathological states - Structural and functional
consequences of denervation (rats)
POlHL-14388-07 0179 Regulation of the circulation in
pathological states ■ Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
POlHL-14388-07 0183 Regulation of the circulation in
pathological states - Vasopressin in cardiovascular
regulation (dogs, rats)
** POlHL-1438807 0186 Regulation of the circulation in
pathological states - Angiotension in modulation of
neurogenic vasoconstriction
POlHL-1438807 0207 Regulation of the circulation in
pathological states • Brain and renin-angiotension
interaction in spontaneous hypertension (rats)
POlHL-1438807 9002 Regulation of the circulation in
pathological states - Core immunoassay laboratory (rabbits)
R01HL14397-07 Hypertension Angiotensin and
prostaglandin pharmacology (animals)
R01HL14914-06 Autoregulation of glomerular filtration
rate (rats)
ROlHL-1494407 Renal vascular reactivity in hypertensive
patient
P01HL14985-07 0012 Adaptation to hypoxia ■ Direct
effect of hypoxia on pulmonary vascular smooth muscle
(rats, dogs)
R01HLI5416-06 Cardiovascular control in normal and
disease states (dogs, baboons)
R01HL1632005 Vasoactive peptides which stimulate
smooth muscles (rats, human)
R01HL17366-05 Mechanisms in the production of renal
hypertension (rabbits, dogs)
ROlHL-17401-03 Mechanisms in angiotensin induced
hypertension (cats, dogs)
P50HL-1 7646-04 0016 Study of ischemic heart disease -
Humoral factors in ischemic heart rhythm, mechanical
performance (dog. rabbit)
ROlHL-17847 04 Cardiovascular and renal functions of
marmots
ROIHL 18148-04
ROlHL-18259-03
prostaglandins
P50HL-1831803 0015 Pathogenesis and complications of
hypertension - Cultured smooth muscle cells and
microvessel metabolism (mammals)
P50HL-18323-04 0011 SCOR hypertension center •
Endocrine profiling on a selected normal population
(human)
P50HL-18323-04 0037 SCOR hypertension center ■
Adrenocortical factors in childhood hypertension
* P50HL-I832304 0044 SCOR hypertension center -
Angiotensin blockade to identify angiotensin II factor in
hypertension (human)
ROIHL-18579-03 Vasoactive hormones and blood pressure
regulation (dogs. rats, rabbits)
R01HL18711-03
chicks)
ROlHL-18862-02
(dogs)
' ROlHL-1889303
receptor (rats)
ROlHL-18995-04 Cardiovascular determinants of
catecholamine release (dogs)
ROIHL-19209-03 Role of ADH in experimental renal
hypertension (dogs, rats)
P50HL-19362-02 0010 A/S SCOR-Atherosclerosis in
nonhuman primates - Antihypertensive therapy -
Atherogenesis in experimental hypertension (baboon)
ROlHL-19366-03 Renal Starling forces in experimental
conditions (rats, rabbits)
' ROlHL-19428-03 Role of angiotensin sensitivity in renin
release (human)
ROlHL-19538-03 Synthesis of potential antihypertensive
agents
400
Circulatory system effects of angiotensin
Adrenal catecholamine secretion
Controlled intratissue release of
Electrophysiology of heart cells (rats.
Thirst and its contribution to edema
Mechanism of angiotensin action -Role of
ROlHL-1965303
analogs (rats)
ROlHL-200 54-02 Cultured blood vessel cells-
Pathophysiology (human, animals)
ROlHL-20429-03 Study of effects of diabetes reactivity
(miniature pigs, rats)
ROlHL-20768-02 Mechanisms of circulatory regulation in
heart failure (guinea pigs)
ROlHL-20895-03 0010 Cineangiographic studies of
cardiovascular system ■ Cortical necrosis and acute renal
failure (human, dogs. rats, rabbits)
R23HL 21066-02 Angiotensin and prostaglandin control of
aldosterone (rats)
ROIHL 21351-02 Renal and vascular control by
sympathetic ganglia (animals)
ROlHL-21394-02 Pulmonary angiotensin-converting enzyme
(rabbits)
ROlHL-21799-01 Circumventricular sites of pressor action
of angiotensin II (rats)
ROlHL-21800-01
excretion
ROlHL-22051-01
release (human)
ROlHL-22411-01
Angiotensin effects on water intake and
Role of angiotensin II in vasopressin
The spontaneously hypertensive kidney
Neuroendocrine involvement in
hypertension (rats)
" R01HL22617-01 Angiotensin, hypertension and the CNS
(sheep)
ROlHL-22836-01
(rats)
R01HL22868-01 Presynaptic regulatory mechanisms in
hypertension (rats, dogs)
** ROlHL-22990-01 Angiotensin II receptors -Mechanisms of
regulation (rats)
PEPTIDES, VASOACTIVE PEPTIDES,
ANGIOTENSINOGEN
ROlHL-15808-06 Role of angiotensinogen in hypertension
and stroke (human, rabbits)
ROlHL-1856103 Radioimmunoassay of angiotensinogen
(human)
PEPTIDES, VASOACTIVE PEPTIDES, ANTIRENIN
ROlHL-15528-05 Renin kinetics in hypertensive and
uremic plasma (human, dogs)
ROlHL-17243-05 Cause of chronic experimental renal
hypertension (dogs, rabbits)
ROlHL-17947-04 Experimental renal and neurogenic
hypertension (human, animals)
PEPTIDES, VASOACTIVE PEPTIDES, HYPOTENSIVE
PEPTIDES
SEE ALSO PEPTIDES, VASOACTIVE PEPTIDES, KALLIDIN
ROlHL-14397-07 Hypertension -Angiotensin and
prostaglandin pharmacology (animals)
ROlHL-18993-03 Biological investigations of substance P
*• ROlHL-18994-03 Substance P-Occurrence, pharmacology
and physiology (mammals non-human, human)
PEPTIDES, VASOACTIVE PEPTIDES, KALLIDIN
P50HL-14159-08 0020 Specialized center of research in
hypertension - Renin-mineralocorticoid system in
hypertension (human, rat, dog)
POIHL-14388-07 0179 Regulation of the circulation in
pathological states - Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
** POlHL-14388-07 0223 Regulation of the circulation in
pathological states - Kallikrein-kinin system in hypertension
(rats)
POlHL-14388-07 0224
pathological states •
(human)
POlHL-14388-07 0230
pathological states
Regulation of the circulation in
Kallikrein-kinin system in hypertension
Regulation of the circulation in
■ Effects of indomethacin in patients
with carcinoid syndrome
' P60HL-15160-07 0016 Center for sickle cell disease -
Kinin and plasmin system in sickle cell disease (human)
' ROlHL-15690-07 Hydrolytic enzymes of blood in health
and disease (human, animals)
P01HL15832-06 0007 Chemical-structural predispositions
to lung injury - Inactivafion of vasoactive agents by the
lung (human, rats, cats, dogs)
POlHL-15832-06 0010 Chemical-structural predispositions
to lung injury - Kinin generating systems in pulmonary
disease (human, animals)
R01HL16642-05 Biochemistry and pathophysiology of
plasma kallikrem (human, animals)
ROlHL-17402-04 Mechanism of contact activation of
intrinsic clotting (human)
ROlHL-18526-03 Kinins and the human lung
ROlHL-1861804 Purification and function of human HMW
kininogen
ROlHL-1884504 Regulation of renal circulation and salt
excretion (rats, dogs)
ROlHL-18882-02 Hormones in hypertension (human)
ROlHL-19836-03 Kinin inhibitors detected by use of
receptors (cattle)
ROlHL-21544-02 Proteins of coagulation and Hageman
factor pathways (human, goats)
ROlHL-22896-01 Immediate metabolic fates of kinins and
angiotensins (rat, rabbit, guinea pig)
PEP
PEPTIDES, VASOACTIVE PEPTIDES, KALLIDIN-9
ROlHL-05883-18 0001 Reflex control of resistance and
capacitance vessels - Naturally occurring vasoactive
substances and the vascular neuroeffectors (dog)
P01HL10342-13 0028 The integrated function of
respiration and circulation Mediator release,
hemodynamics and respiratory function in anaphylaxis
(dogs)
ROlHL-12421-10 Pathophysiology of circulatory shock
(dogs, baboons)
ROlHL-12677-10 Surgical physiologic studies of isolated
kidneys (dogs, rats)
ROlHL-12684-09 Angiotensin I and converting enzyme in
hypertension (human, primates, dogs)
ROlHL-13315-08 Disposition of vasoactive hormones in
mammalian lung (rats, rabbits, human)
" ROlHL-13909-27 Physiochemistry and immunology of
macromolecules
P50HL1415307 0013 Johns Hopkins Lung Center--
Chronic diseases of airways - Pulmonary mechanics and
mediators of allergic reactions (guinea pigs, human)
** P50HL-14153-07 0015 Johns Hopkins Lung Center-
Chronic diseases of airways ■ Kinins and human lung
P50HL-14187-07 0014 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses - Metabolism
and actions of vasoactive peptides in lung (human,
mammals)
P50HL-)4218-07 0017 Pulmonary SCOR -Newborn lung
center - Transvascular fluid exchange, vasoactive mediators
in RDS (sheep, cat)
POlHL-1438807 0157 Regulation of the circulation in
pathological states ■ Autoregulation of renal blood flow and
distribution in sodium excretion control
POlHL-14388-07 0230 Regulation of the circulation in
pathological states • Effects of indomethacin in patients
with carcinoid syndrome
ROlHL-14456-07 Lung metabolism -Enzymes in the
pulmonary circulation (human, animals)
P60HL15160-07 0016 Center for sickle cell disease -
Kinin and plasmin system in sickle cell disease (human)
ROIHL- 15580-06 Humoral control of pulmonary and
systemic circulation (animals)
" POlHL-15832-06 0010 Chemical-structural predispositions
to lung injury • Kinin generating systems in pulmonary
disease (human, animals)
R01HL1606605 Studies on neurogenic control of the
circulation (human, dogs)
ROlHL-16320-05 Vasoactive peptides which stimulate
smooth muscles (rats, human)
** ROlHL-16642-05 Biochemistry and pathophysiology of
plasma kallikrein (human, animals)
POIHL- 17382-05 0001 Chemical mediators of acute
pulmonary disorders ■ Chemical mediators and respiratory
mechanics in humans
P01HL1738205 0003 Chemical mediators of acute
pulmonary disorders - Chemical mediators relevant to
allergic reactions (human, guinea pigs)
ROlHL-17768-04 Development of collateral ventilation
(dogs. fish, horses)
" ROlHL-18259-03 Controlled intratissue release of
prostaglandins
P50HL1831803 0015 Pathogenesis and complications of
hypertension • Cultured smooth muscle cells and
microvessel metabolism (mammals)
'* P50HL18323-04 0033 SCOR hypertension center - Core
laboratory-Renin. aldosterone and bradykinin methodology
ROlHL-18618-04 Purification and function of human HMW
kininogen
R01HL18624-03 Study of kinins in hypertension and other
diseases (human)
R01HL18718-04
reactivity (dogs)
ROlHL-18936-02
studies (rat)
ROlHL-19229-02
Prostaglandin precursors and vascular
Heart preservation and transplantation
Prostaglandins and hypertension (human.
rats. dogs, rabbits)
ROlHL-19374-03 Pharmacology of kinins in cardiovascular
disease (rats, rabbits)
ROlHL-19455-03 Role of endothelial cells in vascular
permeability (tissue culture)
ROlHL-19836-03
receptors (cattle)
ROlHL-21394-02
(rabbits)
ROlHL-2 1568-02
(animals)
ROlHL-22177-02
Kinin inhibitors detected by use of
Pulmonary angiotensin-converting enzyme
Cell biology of the alveolar-capillary unit
•Excludes routine methodology OR covers only general projects which preclude indexing
•'Onented significantly to above subject.
at the specific level.
M Grant has subprojects describing specific research aspects
See Appendix for investigator's name and grant number.
Mechanisms of control of pulmonary
smooth muscle (dogs)
ROlHL-22561-01 Hormonal control of mesenteric
circulation (cats)
ROlHL-23211-01 Active normoxic pulmonary vasodilatation
(rat. dog, sheep)
PEPTIDES, VASOACTIVE PEPTIDES, KALLIKREIN
ROlHL-01661-27 Hemostatic mechanisms (human)
POlHL-0631417 0062 Immunologic mechanisms in
cardiovascular disease ■ Immunologic renal vascular
disease (human, animals)
ROlHL-09921-13 Mechanisms related to congestive heart
failure (dogs, human, rat)
(contd)
.^ss^.
NP
PSOHL 1415307 OOU Johns Hopkins Ung Ctntet
Chronic diseasas of airways Madiatot foleaso in asthma
(human)
PSOHl 14153 07 0015 k>hns Hopkins lun| Center
Chronic diseases ol airviavs Kinins and human lung
P50HL 1415908 0020 Speciahied center ol research in
hypertension Renin mineialocorticoid system in
hypertension (human, rat. dog)
PSOHL 14187 07 0014 Pulmonary SCOR Chemical
mediators m pulmonary vascular responses Metabolism
and actions ol vasoactive peptides in lung (human,
mammals)
POIHI 1438807 0179 Regulation ot the circulation in
pathological states Cultured muscle cells and their cross
innervation in vitro (rats, sheep)
POIHL 1438807 0223 Regulation ol the circulation in
pathological states KallikreinkinJn system in hypertension
(rats)
POIHL 1438807 0224
pathological states
(human)
POIHL 1438807 0230
pathological states
Regulation ol the circulation in
Kallikreinkinin system in hypertension
Regulation of the circulation in
Effects ol indomethacin in patients
with carcinoid syndrome
P60HL1516007 0016 Center for sickle cell disease •
Kinin and plasmin system in sickle cell disease (human)
ROlHL-1569007 Hydrolytic enzymes of blood in health
and disease (human, animals)
** ROIHL- 1583905 Physiological role of isorenin and
kallikrein (animals)
POIHL 1641 104 0002 Blood systems in coagulation and
vessel disease - Early stages of coagulation and
cardiovascular disease (human, rabbits)
*♦ ROlHL-1664205 Biochemistry and pathophysiology of
plasma kallikrein (human, animals)
POlHL-17382-05 0001 Chemical medutors of acute
pulmonary disorders Chemical mediators and respiratory
mechanics in humans
ROIHL'17402'04 Mechanism of contact activation of
intrinsic clotting (human)
** R01HL1770504 Kallikreinkinin system in hypertension
(human, rats, dogs)
** R01HL18507-03 Clinical studies of Fletcher factor
(human)
R01HL18526-03 Kinins and the human lung
P01HL18575-03 0002 Mechanisms of vascular changes
in hypertension - Endocrines, electrolytes, and
hemodynamics in hypertension (pigs)
** R01HL18579-03 Vasoactive hormones and blood pressure
regulation (dogs, rats, rabbits)
** R01HL18618-04 Purification and function of human HMW
kininogen
** ROlHL-18624-03 Study of kinins in hypertension and other
diseases (human)
P01HL1882702 0002 Platelet vessel wall interactions in
thrombogenesis - Interactions of vessel wall
macromolecules with factor XII (human, rats)
P50HL-18828-03 0003 Specialized center of research in
thrombosis - Structure and function of plasma coagulation
inhibitors (human)
ROIHL'18845-04 Regulation of renal circulation and salt
excretion (rats, dogs)
** R01HL-18882-02 Hormones in hypertension (human)
R01HL19287-03 The antihypertensive function of the
renal medulla (human, rats, rabbits)
** ROlHL-19374-03 Pharmacology of kinins in cardiovascular
disease (rats, rabbits)
•* ROlHL-19870-03 Hypertensive progeny-Physical and
humoral precursor search
** ROlHL-20594-02 Renal enzymes that regulate blood
pressure (human, rats)
ROlHL-20846-02 Purification of bovine plasminogen
proactivator
ROlHL-21544-02 Proteins of coagulation and Hageman
factor pathways (human, goats)
ROlHL-21975-01 Studies on normal and abnormal factor
IX (human, dogs, cows)
ROlHL-22225-01 Hormonal regulation of blood pressure
and blood flow (human, animals)
ROlHL-22298-02 Origins of hypertension (human)
** ROlHL-22939-01 Human kinin and fibrinolytic systems
and renal disease (human)
ROlHL-232 11-01 Active normoxic pulmonary vasodilatation
(rat, dog, sheep)
** NOlHV-72943-01
antagonists
" NOIHV-72944-02
antagonists
" N01HV-72946-02
antagonists
PEPTIDES, VASOACTIVE PEPTIDES, RENIN
SEE ALSO ADRENAL GUNDS DISORDERS,
HYPOALDOSTERONISM, HYPORENINEMIC
ROlHL-06143-18 Response of the totally denervated heart
to exercise (dogs)
POlHL-06835-17 0030 Cardiovascular disease - Synthesis
and pharmacology of angiotensin antagonists (rats, cats)
POlHL-06835-17 0034 Cardiovascular disease Studies
of phospholipase A2 in serum (rats, dogs)
•* POlHL-06835-17 0036 Cardiovascular disease
Purification of dog renin
Prostaglandin and kallikrein kinin system
Prostaglandin and kallikrein kinin
Development of kallikrein -Kinin system
Renal
401
POIHL 06835 17 0038 Cardiovasculai disease Effect ot
chronic administration ol angiotensin antagonist (rats)
POIHI 06835 1/ 0045 Cardiovascular disease Pressure
volume renin relationship in human hypertension
POIHL 06835 17 0046 Cardiovascular disease Renin
activity during salt depletion in essential hypertension
(human)
POIHI 0683517 0049 Cardiovascular disease Selective
hypoaldosteronism (human)
POIHL 06835 17 0050 Cardiovascular disease 18
Hydroxylase block in the 17 alpha hydroxylase deficiency
syndrome (human)
POIHL 06835 17 0057 Cardiovasculii disease - Studies
on cardiac hypertrophy
POIHL 06835 17 0059 Cardiovascular disease -
Metyrapone induced hypertension in dog
R01H10697518 Pathogenesis and prevention of
hypertension (rats)
POIHL 08682 15 0026 Regulation of the cardiovascular
system Hypertension -High renin vs low renin (dog)
POIHL 08682 15 0027 Regulation of the cardiovascular
system Cardiac mechanoreceptors- Reflex regulation of
renal function (dogs)
ROIHL 1061213 0020 Humoral factors in heart failure
and hypertension The control of renin release in the dog
POlHL'lMU-ll 0014 Thrombosis and atherosclerosis
program Role of adrenal in human essential hypertension
POIHL 11678-11 0051 Cardiovascular dynamics and their
control Transient glomerular filtration dynamics (dogs)
P01HL12738 10 0111 Physiologic pharmacology and its
clinical applications Cardiovascular pharmacology (dogs)
ROIHL'12827-08 Regulation of sodium excretion (dogs,
rats)
R01HL12990-09 Control of antidiuretic hormone secretion
and metabolism (dogs, rats, rabbits)
POIHL 13262-07 OOU Arterial wall in atherosclerosis ■
Role of hypertension in atherosclerosis (human, monkey,
dog)
R01HL13408-05 Environmental-genetic interactions in
hypertension (rats)
ROIHL 13587-06 Synthesis of renin inhibitors and analog
phosphatides (rats)
ROIHL'1359508 Renin and vascular hyper-reactivity in
hypertension (human, rats)
* ROlHL-13917 20 Secretion and effects of adrenal
hormones (human, rabbits, sheep)
ROlHL-14148-07 0007 The regional circulations - Salivary
composition in hypertension (human)
ROlHL-1414807 0008 The regional circulations
circulation in hypertensive patients (also dogs)
P50HL14159-08 0008 Specialized center of research in
hypertension - Renal function and sodium metabolism in
hypertension (rats, human, rabbits)
* P50HL-141 59-08 0020 Specialized center of research in
hypertension - Renin-mineralocorticoid system in
hypertension (human, rat, dog)
P50HL1415908 0022 Specialized center of research in
hypertension Core laboratory
P50HL-14192-08 0002 Specialized center of research in
hypertension ■ Hypertensive patients with renal artery
stenosis
* P50HL-14192-08 0003 Specialized center of research in
hypertension - Prostaglandins as mediators of renin
secretion (human, dog)
* P50HL14192-08 0004 Specialized center of research in
hypertension - Isolation and characterization of pure renin
(swine, rats, human, rabbits)
* P50HL-1419208 0005 Specialized center of research in
hypertension - New techniques for recognition of
renovascular hypertension (human, dogs)
P50HL-14192-08 0007 Specialized center of research in
hypertension - Role of new mineralocorticoids in
hypertension (human, rats)
POlHL-1438807 0157 Regulation of the circulation in
pathological states - Autoregulation of renal blood flow and
distribution in sodium excretion control
POlHL-14388-07 9002 Regulation of the circulation in
pathological states - Core immunoassay laboratory (rabbits)
* ROlHL-1583706 Renin and cardiac hypertrophy in
hypertension (rats)
* ROlHL-15839-05 Physiological role of isorenin and
kallikrein (animals)
ROlHL-169 18-05 Role of steroids in hypertension (human)
* ROlHL-17364-04 'Big renin" -Biochemical and clinical
studies (human)
ROlHL-17749-03 Adrenocortical factors in human
hypertension (human)
* ROlHL-17896-03 Dehydropeptide renin substrates
* ROlHL-18019-04 The endocrine kidney in hypertension
(mice)
P50HL-183 18-03 0004 Pathogenesis and complications of
hypertension - Steroid and renin profiles in hypertension
(rats, human)
P50HL-183 18-03 0011 Pathogenesis and complications of
hypertension - Adrenergic function -Renin and
mineraiocorticoid activity (human)
P50HL-183 18-03 0013 Pathogenesis and complications of
hypertension - Humoral factors and renal function in
human hypertension
* P50HL 18318-03 0018 Pathogenesis and complications of
hypertension - Plasma renin activity in chronic ischemic
heart disease (human)
Renin
Core
PEP
P50HI 18323 04 OOU SCOR hypertension center
Endocrine profihng on a selected normal population
(human)
P50H1 18323 04 001? SCOR hypertension center
as a risk (actor (human)
P50HL 18323 04 0033 SCOR hypertension center
laboratory Renin, aldosterone and bradykinin methodology
P50HI 18323 04 0042 SCOR hypertension center Blood
viscosity and blood volume in hypertensive disease
(human, dog)
P50HL 18323 04 0045 SCOR hypertension center
Laboratory programs Prorenm (human)
P50HL 18323 04 0046 SCOR hypertension center
Coronary artery bypass surgery Associated hypertension
(human)
P50HL 1832304 0047 SCOR hypertension center
Transcendental meditation and self hypnosis Hypertension
treatment (human)
ROIHL 1834004 Electron microscopy of the
juxtaglomerular apparatus (rats)
ROIHL 1856103 Radioimmunoassay of angiotensinogen
(human)
P01HL1857503 0005 Mechanisms of vascular changes
in hypertension Renin synthesis in normotensive and
hypertensive pigs (also rats, dogs)
ROIHL 18730-03 Role of mineralocorticoids in low renin
hypertension (human, rats)
ROIHL 1886202 Thirst and its contribution to edema
(dogs)
ROIHL 1889102 Electrolyte intake and blood pressure in
hypertension (human)
R01HL18948-03 Pulseless flow and circulatory assistance
(dogs, calves)
ROlHL-19057-03 Catecholamines and cyclic AMP in
cardiovascular system (rats, dogs)
ROlHL-1922902 Prostaglandins and hypertension (human,
rats, dogs, rabbits)
R01HL19246-03 Regression of cardiac hypertrophy -
Myocardial and renal (human)
P50HL19362-02 0010 A/S SCOR Atherosclerosis in
nonhuman primates - Antihypertensive therapy -
Atherogenesis in experimental hypertension (baboon)
* ROIHL- 19428-03 Role of angiotensin sensitivity in renin
release (human)
■ R01HL19517-03 Synthesis of inhibitors for the study of
renal renin (dogs, monkeys)
ROlHL-19539-03 Pathology of hypertensive-associated
arteritis (rabbits)
ROlHL-19644-03 Etiological factors in hypertension
(human, dogs, rats)
ROlHL-19653-03
analogs (rats)
' ROlHL-20 189-01
(rabbits)
' ROlHL-20278-02
(rats)
* ROlHL-20594-02
pressure (human, rats)
ROlHL-21112-02
secretion in man
ROlHL-21210-01
surgery (human)
* R23HL-2124702
* ROlHL-2127401
analysis (human)
* ROlHL-21308-01 Prostaglandins and local control of the
circulation (rats, dogs)
Circulatory system effects of angiotensin
Effects of renin on atherogenesis
Cellular mechanisms of renin secretion
Renal enzymes that regulate blood
rats)
Aldosterone binding, clearance, and
Acute renal failure following cardiac
Purification of renal renin (human)
Prorenin-Physiological and biochemical
ROlHL-21877-01
ROlHL-22288 01
function (mice)
ROlHL-22298-02
ROlHL-22390-01
R23HL-2272801
ROlHL-2360201
Iso-renins in the hypertensive rat
Renin and precursors-Structure and
Origins of hypertension (human)
Effect of chloride on renin (rats, dogs)
Neural control of renin secretion (dogs)
Physiology of renin, aldosterone and
prostaglandin (human, rats, dogs)
PEPTIDES, VASOACTIVE PEPTIDES, RENIN-
ANGIOTENSIN SYSTEM
ROlHL-02493-22 Kidney function in experimental heart
failure (dogs, rats)
R01HL03303-21 Factors regulating electrolyte excretion by
the kidney (human, dogs)
P01HL06835-17 0037 Cardiovascular disease - Cardiac
hypertrophy in spontaneously hypertensive rat
P01HL0683517 0038 Cardiovascular disease - Effect of
chronic administration of angiotensin antagonist (rats)
ROIHL'07835'17 Experimental hypertension and renal
circulation (rats, rabbits)
ROIHL'08570'15 Pharmacologic and reflex influence on
vascular tone (dogs, rabbits)
POlHL-08682-15 0026 Regulation of the cardiovascular
system - Hypertension-High renin vs low renin (dog)
ROlHL-10182-13 Circulatory function and electrolytic
metabolism (dogs, human)
M ROlHL-10612-13 Humoral factors in heart failure and
hypertension
" ROlHL-10612 13 0018 Humoral factors in heart failure
and hypertension - The pathogenesis of experimental renal
hypertension (dogs, rabbits, rats)
** ROlHL-10612-13 0019 Humoral factors in heart failure
and hypertension - Pathogenesis of hypertension in the
spontaneous hypertensive rat
(contd)
'Excludes routine methodotogy OR cavers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
PEP
R01HL10612-13 0021 Humoral factors in heart failure
and hypertension - The control of aldosterone secretion
(dogs)
ROlHL-11046-12 Renin, angiotensin, steroids, ions and
blood pressure (human, sheep, rabbits)
M POlHL-1167811 Cardiovascular dynamics and their
control
P01HLn678-ll 0040 Cardiovascular dynamics and their
control - Control of plasma potassium concentration (dogs)
POlHL-1 1678-11 0046 Cardiovascular dynamics and their
control ■ Regulation of aldosterone secretion and related
factors (dogs)
** POlHL-1 1678-11 0063 Cardiovascular dynamics and their
control - Renin-angiotensin system -Control of renal
hemodynamics, electrolyte excretion
POlHL-1 1678-11 0054 Cardiovascular dynamics and their
control - Renal medulla -Control of renal hemodynamics,
electrolyte excretion (dogs)
POlHL-1 1678-11 0067 Cardiovascular dynamics and their
control - Angiotension II, sodium excretion and renal
hemodynamics (dogs)
ROlHL-12677-10 Surgical physiologic studies of isolated
kidneys (dogs, rats)
** ROIHL- 12684-09 Angiotensin I and converting enzyme in
hypertension (human, primates, dogs)
ROlHL-12990-09 Control of antidiuretic hormone secretion
and metabolism (dogs, rats, rabbits)
ROlHL-13587-06 Synthesis of renin inhibitors and analog
phosphatides (rats)
** ROlHL-13595-08 Renin and vascular hyper-reactivity in
hypertension (human, rats)
R01HL13634-08 Renal hypertension in pregnancy (sheep)
ROlHL-13917-20 Secretion and effects of adrenal
hormones (human, rabbits, sheep)
ROlHL-13929-06 Single nephron response to chronic
obstruction (frogs, rats)
P50HL-14159-08 0021 Specialized center of research in
hypertension - Genetic studies of the physiology of
hypertension (human, rats)
** ROlHL-14306-07 Quantification of arterial pressure control
(dogs)
POlHL-14388-07 0179 Regulation of the circulation in
pathological states - Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
POlHL-14388-07 0183 Regulation of the circulation in
pathological states - Vasopressin in cardiovascular
regulation (dogs, rats)
P01HL14388-07 0186 Regulation of the circulation in
pathological states - Angiotension in modulation of
neurogenic vasoconstriction
*• P01HL14388-07 0188 Regulation of the circulation in
pathological states - Renin-angiotensin system in the sheep
fetus
*• POlHL-14388-07 0207 Regulation of the circulation In
pathological states - Brain and renin-angiotension
interaction In spontaneous hypertension (rats)
P01HL14388-07 0223 Regulation of the circulation in
pathological states - Kallikrein-kinin system in hypertension
(rats)
P01HL14388-07 0224 Regulation of the circulation in
pathological states - Kalllkrein-kinin system in hypertension
(human)
ROlHL-14397-07 Hypertension -Angiotensin and
prostaglandin pharmacology (animals)
•* ROlHL-14509-07 Hypertension -Chemistry and biophysics
of angiotensin
ROlHL-14914-06 Autoregulation of glomerular filtration
rate (rats)
ROlHL-14944-07 Renal vascular reactivity in hypertensive
patient
ROlHL-15124-05 Genesis of hypertension in renal disease
(human, dogs)
** R01HL-15307-06 Central nervous control of renin and
blood pressure (dogs)
ROlHL-15416-06 Cardiovascular control in normal and
disease states (dogs, baboons)
** ROIHL- 15528-05 Renin kinetics in hypertensive and
uremic plasma (human, dogs)
ROlHL-15808-06 Role of angiotensinogen in hypertension
and stroke (human, rabbits)
•* R01HL-I5839-05 Physiological role of isorenin and
kallikrein (animals)
ROlHL-16496-04 Prostaglandins and renin experimental
hypertension (rabbits)
ROlHL-16642-05 Biochemistry and pathophysiology of
plasma kallikrein (human, animals)
ROlHL-17243-05 Cause of chronic experimental renal
hypertension (dogs, rabbits)
'* ROlHL-1 736605 Mechanisms in the production of renal
hypertension (rabbits, dogs)
ROlHL-17401-03 Mechanisms in angiotensin induced
hypertension (cats, dogs)
ROIHL- 17403-03 Metabolic control of cardiac output
(dogs)
ROlHL-17487-04 Adrenergic-vasoregulation interactions in
hypertension (human)
ROIHL-17847-04 Cardiovascular and renal functions of
marmots
POlHL'17871-04 0009 Kidney, sodium, cardiac output,
arterioles and hypertension ■ Kidney, sodium, cardiac
output, arterioles and hypertension
402
ROlHL-17947-04 Experimental renal and neurogenic
hypertension (human, animals)
ROlHL-17958-04 Circulatory effects of operant
cardiovascular control (baboons)
ROIHL-18019-04 The endocrine kidney in hypertension
(mice)
R01HL-I8027-03 New vasoactive (actors and their role in
hypertension (human, dogs, rats)
P50HL-18318-03 0001 Pathogenesis and complications of
hypertension - Core clinical program
P50HL-I8318-03 0003 Pathogenesis and complications of
hypertension - Core biochemical laboratory
P50HL-183 18-03 0013 Pathogenesis and complications of
hypertension - Humoral factors and renal function in
human hypertension
P50HL 18318-03 0014 Pathogenesis and complications of
hypertension - Arterial metabolism and atherogenesis (rat.
rabbit)
" P50HL-183 18-03 0019 Pathogenesis and complications of
hypertension - Renin-angiotensin system in blood pressure
regulation (human, rat, dog)
M P50HL-I8323-04 SCOR hypertension center
** P50HL-18323-04 0011 SCOR hypertension center -
Endocrine profiling on a selected normal population
(human)
" P50HL- 183 23-04 0012 SCOR hypertension center - Renin
as a risk factor (human)
P50HL- 183 23-04 0037 SCOR hypertension center -
Adrenocortical factors in childhood hypertension
** P50HL-18323-04 0043 SCOR hypertension center -
Pharmacology-Renin-aldosterone mechanisms in essential
hypertension (human)
P50HL-18323-04 0044 SCOR hypertension center -
Angiotensin blockade to identify angiotensin II factor in
hypertension (human)
** P50HL 18323-04 0046 SCOR hypertension center -
Coronary artery bypass surgery -Associated hypertension
(human)
•♦ ROlHL-18340-04 Electron microscopy of the
juxtaglomerular apparatus (rats)
POlHL-18575-03 0002 Mechanisms of vascular changes
in hypertension - Endocrines. electrolytes, and
hemodynamics in hypertension (pigs)
POlHL-18575-03 0011 Mechanisms of vascular changes
in hypertension - Chemistry laboratory core facility
ROlHL-18579-03 Vasoactive hormones and blood pressure
regulation (dogs, rats, rabbits)
R01HL18624-03 Study of kinins in hypertension and other
diseases (human)
ROlHL-18845-04 Regulation of renal circulation and salt
excretion (rats, dogs)
** ROlHL-18862-02 Thirst and its contribution to edema
(dogs)
** ROIHL- 1 8882-02 Hormones in hypertension (human)
POIHL- 189 74-03 0006 Experimental neurogenic
hypertension program - Model of sustained arterial
hypertension (cats)
ROlHL-18995-04 Cardiovascular determinants of
catecholamine release (dogs)
ROIHL- 191 34-04 Angiotensin, prostaglandins, adrenergic
interactions (rats, rabbits)
** ROlHL-19209-03 Role of ADH in experimental renal
hypertension (dogs, rats)
ROlHL-19320-03 Angiotensin neuropharmacology-
Relationship to sodium
ROlHL-19428-03 Role of angiotensin sensitivity in renin
release (human)
** ROlHL-19467-03 Regulation of blood pressure (rats, dogs)
" ROlHL-19825-02 Renin-volume interactions in coarctation
hypertension (dogs)
** ROlHL-20455-03 Role of systemic hypertension on diabetic
retinopathy (human)
M ROlHL-20572-02 Hemodynamic relations to metabolism in
hypertension
ROlHL-20572-02 0003 Hemodynamic relations to
metabolism in hypertension - Cardiac output and organ
blood flow in hypertension (rats)
ROlHL-20787-02 Thromboxanes and prostaglandins -
Biochemical pharmacology (rabbits, human)
R23HL-21066-02 Angiotensin and prostaglandin control of
aldosterone (rats)
** ROlHL-21092-02 Factors other than renin in renal
hypertension (rats)
** R23HL-2I291-02 Renin-mineralocorticoid axis in
hypertensive diabetics (human)
ROlHL-22051-01 Role of angiotensin II in vasopressin
release (human)
ROlHL-22225-01 Hormonal regulation of blood pressure
and blood flow (human, animals)
ROIHL-22306-01 Renal catecholamines- Pathophysiology
of hypertension (dogs)
ROlHL-22387-01 Metalloenzymes and disease
R23HL-22438-01 The etiology of genetic hypertension
(rats)
R23HL-22728-01 Neural control of renin secretion (dogs)
** ROlHL-22977-01 Role of vasoconstrictor mechanisms in
heart failure (human, dogs)
ROlHL-23201-01 Mechanisms of hypertension (human,
rats)
ROlHL-23600-01 Ions, water, and hypertension (human,
dogs, rats)
PER
PEPTIDES ANALOGS
ROlHL-14397-07 Hypertension -Angiotensin and
prostaglandin pharmacology (animals)
ROlHL-18679-04 Synthetic protease inhibitors
** ROlHL-18993-03 Biological investigations of substance P
ROlHL-19428-03 Role of angiotensin sensitivity in renin
release (human)
ROIHL 22387 01 Metalloenzymes and disease
PEPTIDES STRUCTURE
SEE PROTEINS-PEPTIDES STRUCTURE
PEPTIDES TEMPLATES
SEE NUCLEIC ACIDS. MRNA
PERCEPTION
SEE SENSORY-PERCEPTUAL PROCESSES. PERCEPTION
PERCEPTION-MEDITATION CONTINUUM
SEE PSYCHIC ACTIVITY LEVEL, TROPHOTROPIC STATE
PERFORMANCE, MENTAL
SEE PSYCHOLOGY, PERFORMANCE
PERFUSION
SEE DOSAGE AND ROUTE, PERFUSION
PERICARDIOTOMY
SEE HEART SURGERY, PERICARDIOTOMY
PERICARDITIS
SEE HEART DISORDERS, PERICARDITIS
PERINATAL
SEE PREGNANCY, PERINATAL
PERINATAL CARE
SEE HEALTH CARE SERVICES, MATERNAL AND INFANT CARE
PERINATAL DISTRESS SYNDROME
SEE CONGENITAL ABNORMALITIES. RESPIRATORY DISTRESS
SYNDROME
PERIPHERAL NERVES (GENERAL)
SEE NERVOUS SYSTEM. PERIPHERAL NERVES (GENERAL)
PERIPHERAL NEUROPATHY
SEE NERVOUS DISORDERS PERIPHERAL
PERIPHERAL VASCULAR DISORDERS
SEE CARDIOVASCULAR DISORDERS, PERIPHERAL VASCUUR
DISORDERS
PERIPHERAL VASCULAR SYSTEM
SEE CARDIOVASCULAR SYSTEM, PERIPHERAL VASCUUR
SYSTEM
PERITONEAL DISORDERS
SEE BODY CAVITY DISORDERS, PERITONEAL
PERITONEAL FLUID
SEE BODY CAVITY DISORDERS. PERITONEAL
PERITONEUM
SEE BODY CAVITIES, PERITONEUM
PERMEABILITY
SEE BIOLOGICAL TRANSPORT, MEMBRANE PERMEABILITY
AND TRANSPORT
SEE CARDIOVASCULAR SYSTEM, ENDOTHELIUM
PERMEABILITY
PERMEASES
SEE BIOLOGICAL TRANSPORT, TRANSPORT PROTEINS,
PERMEASES
PEROXIDASE LABELED ANTIBODY TECHNIQUE
SEE IMMUNOLOGICAL TESTS AND IMMUNOASSAY,
PEROXIDASE UBELED ANTIBODY*
PEROXIDASES
SEE ALSO METALLOPROTEINS, CYTOCUPREINS
ROlHL-12526-09 Raman spectra of heme proteins and
related molecules
ROlHL-13651-07 X-ray photoelectron spectroscopy of heme
compounds
ROlHL-13652-08 Metal sites in metalloproteins
(mushroom)
P50HL-14212-07 0006 Correlated studies of pulmonary
fibrosis - Alveolar macrophage physiology (human, rodents.
rabbits)
ROlHL-14508-10 Structure and function of respiratory
hemoproteins
ROlHL-15980-06 Reactions of hemeproteins and oxygen
(cattle)
ROlHL-22252-01 Synthesis of labeled hemes for protein
NMR studies
POlHL-22602-01 0002 Pathophysiology of the
endothelium - Molecular charge and endothelial
permeability (rats, mice)
PEROXIDASES, CATALASE
SEE ALSO METABOLIC DISORDERS INBORN, ACATALASEMIA
ROlHL-02558-22 Structure-function relationships in the
heme proteins (human, cattle)
POlHL-09011-15 0015 A research and resource program
in blood - Regulation of synthesis and transport of diverse
proteins in liver (rats)
*E«chid« rotifin* methodokiiy OR covers only general projects which preclude indexing at the specific level,
••"iiif'en M niffcantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
(contd)
.388^5
PER
ROIHL 12526-09 Raman sptdia ol heme proteins and
related molecules
ROIHL IS98006 Reactions of hemeproteins and o«y|!en
(cattle)
POIHI 167480S 0004 Cellular and immunological basis
of pulmonary diseases Cellulai and immunological
processes in pulmonary delense systems
ROIHI 1815704 Subcellular events in atherosclerosis
(human, rabbits, cahres)
ROIHL 1977903 Biochemical basis ol oxygen damage to
lung cells (guinea pigs, rats)
ROIHL 203S2 02 Defenses of lung cells agarnst oxygen
toxicity (human, animals)
PEROXIDASES, GLUTATHIONE PEROXIDASE
POIHL 1674805 0004 Cellular and immunological basis
ol pulmonaiy diseases Cellular and immunological
processes in pulmonary delense systems
ROIHL 1771903 Lung injury, substrate utilization, oxygen
toxicity (rats, rabbits, dogs)
■* ROIHL 1850203 Enzymatic regulation of platelet function
(human)
ROIHL'19779'03 Biochemical basis of oxygen damage to
lung cells (guinea pigs, rats)
PEROXIDASES, LACTOPEROXIDASE
R01HL02558-22 Structure-function relationships in the
heme proteins (human, cattle)
ROlHL-16490'04 Structural basis of nephron filtration
(rats, rabbits)
PEROXIDES
SEE ALSO LIPIDS. OXIDIZED LIPIDS. LIPID PEROXIDES
ROIHL 13399-16 Heme protein structure and function
(human, horse, plants, bacteria)
ROIHL- 15580-06 Humoral control of pulmonary and
systemic circulation (animals)
ROlHL-16489-04 Renal prostaglandins-Synthesis and
function (human, dogs, rats)
POIHL- 1787 1-04 0010 Kidney, sodium, cardiac output.
arterioles and hypertension - Renal prostaglandins
metabolism in hypertension (rats, dogs)
** ROlHL-1 792 1-04 Peroxy radicals to prostaglandins in
vessels and lung
** ROlHL-18070-04 Regulation of intrapulmonary airways
and vessels (human, animals)
ROlHL-18259-03 Controlled intratissue release of
prostaglandins
ROIHL- 187 18-04 Prostaglandin precursors and vascular
reactivity (dogs)
POlHL-18827-02 0003 Platelet vessel v»all interactions in
thrombogenesis - Tumor cell and platelets in
thrombogenesis and metastasis (human, animals)
POlHL-19242-02 0004 Study of vascular smooth muscle -
Cyclic nucleotide metabolism in smooth muscle cultures
(human, rats)
POlHL-19717-02 0007 Response of the lung to injury -
Cellular level studies of prostaglandin-like molecules
(cattle)
ROlHL-19997-02 Prostaglandin precursors and intestinal
vasculature (cats, rabbits)
ROlHL-20783-02 Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
ROlHL-20787-02 Thromboxanes and prostaglandins -
Biochemical pharmacology (rabbits, human)
** ROlHL-22219-01 Prostacyclin and peroxides in blood and
membrane disease
PEROXIDES, HYDROGEN PEROXIDE
POlHL-06314-17 0046 Immunologic mechanisms in
cardiovascular disease - Mediators of immune injury
(human, mice)
P50HL-15061-07 0009 Response of lung to injury -
Alveolar macrophages (human, rabbits)
P50HL-15061-07 0012 Response of lung to injury -
Hyperbaric oxygen, carbon monoxide, and ozone or peroxide
toxicity (rats)
ROlHL-1 5668-06 Extracorporeal respiratory gas exchange-
A new approach (dogs)
ROlHL-15980-06 Reactions of hemeproteins and oxygen
(cattle)
PEROXISOMES
SEE CELL COMPONENTS. PEROXISOMES
PERPHENAZINE
SEE PHENOTHIAZINES. PERPHENAZINE
PERSANTINE
SEE DIAZINODIAZINES. DIPYRIDAMOLE
PERSONAL CARE INSTITUTIONS
SEE HEALTH CARE FACILITIES. RESIDENTIAL
PERSONALITY
SEE PSYCHOLOGY, PERSONALITY
PERSONALITY ASSESSMENT-MEASUREMENT
SEE PSYCHOLOGICAL TESTS. PERSONALITY ASSESSMENT-
MEASUREMENT*
PERSONNEL
SEE CHILD WELFARE, CHILD CARE PERSONNEL
PERSPIRATION
SEE SKIN SECRETIONS, SWEAT
403
PERSUASION
Sff PSYCHOIOGY. PERSUASION
PERU
SEE GEOGRAPHICAL SITfS. S AMERICA. PERU
PESTICIDES
SEE ALSO COMMUNICABLE DISEASE CONTROL AGENTS,
ANTIFUNGAL
POIHL 14388 07 9004 Regulation ol the circulation in
pathological states Core biostatistics unit
PESTICIDES, HERBICIDES, PARAQUAT
POIHL 063 70 17 0006 Cardiopulmonary and renal
pathology research center Chemical basis of
ultrastructuial changes in disease (rats)
P50HL 15061 07 0002 Response of lung to injury
Oxidative metabolism, phospholipid synthesis, and response
to toxins (rats)
ROIHL 19720-03 Evaluation of anti fibrotic agents in
pulmonary fibrosis (rats)
ROIHL 23969 01 Surfactant synthesis by type II cells in
vitro (rats)
PESTICIDES, INSECTICIDES, CHLORINATED
HYDROCARBON INSECTICIDES, DDT
ROlHL-2167001 Antiarrhythmic studies on 2 substituted
aminoindenes (dogs)
PESTICIDES BIOLOGICAL EFFECTS (GENERAL)
ROlHl-19720-03 Evaluation of antifibrotic agents in
pulmonary fibrosis (rats)
PETT
SEE RADIOAUTOGRAPHY. RADIONUCLIDE SCANNING.
POSITRON AXIAL TOMOGRAPHY*
PH
SEE BODY FLUID BALANCE. ACID-BASE
PH (HYDROGEN ION CONCENTRATION)
SEE ACIDS-BASES. HYDROGEN-ION CONCENTRATION
PHAGOCYTE DYSFUNCTION OF LEUKOCYTES
(GENERAL)
SEE BLOOD AND RE DISORDERS. LEUKOCYTE DISORDERS.
PHAGOCYTE DYSFUNCTION (GENERAL)
PHAGOCYTES
SEE CELLS. PHAGOCYTES
PHAGOCYTOSIS
SEE CELL INGESTION. PHAGOCYTOSIS
PHANTOM MODELS
SEE MODELS. PHANTOM
PHARAAACOGENETICS
SEE GENETICS. PHARMACOGENETICS*
PHARAAACOLOGY
SEE DRUGS. PHARMACOLOGY
PHARMACOLOGY, BIOCHEMICAL
SEE DRUGS. PHARMACOLOGY. BIOCHEMICAL
PHARMACOLOGY STUDY SECTION
** R01HL-018 13-25 Regulation of metabolism by drugs and
hormones (rats)
** ROlHL-02835-21 Renal transport carrier for organic
compounds (dogs, rats)
** R01HL-D2953-17 Autonomic and cardiovascular
pharmacology (rats, rabbits, dogs, guinea pigs)
** ROlHL-05806-18 Analysis of antiarrhythmic agents (dogs.
rabbits)
** ROlHL-08311-14 Effects of drugs upon myocardial hypoxia
(dogs, turtles)
** ROlHL-08359-14 Morphopharmacology of vascular
adrenergic transmission (rabbits, rats)
** ROlHL-08570-15 Pharmacologic and reflex influence on
vascular tone (dogs, rabbits)
** ROlHL-09283-14 Pharmacology of molluscan hearts (also
rabbits)
** ROlHL-12186-09 Calcium transients in striated muscle
and other cells (mammals, frogs)
** ROlHL-12647-08 Inactivation of norepinephrine in vascular
tissue
** ROlHL-12648-09 Catecholamine metabolism in
hypertensive diseases (human)
** ROlHL-12740-10 Hypocholesterolcmic agents-
Stereochemistry (rats)
** ROlHL-13187-09 Central neural control of cardiovascular
function (cats)
** ROlHL-13306-08 Pharmacological control of cardiac
membrane currents (cattle, rabbits)
** ROlHL-133 15-08 Disposition of vasoactive hormones in
mammalian lung (rats, rabbits, human)
** ROlHL-13339-08 Pharmacology of developing cardiac
tissues (chick embryo)
** ROlHL-13636-08 Effects of pharmacologic agents on heart
metabolism (human, rodents)
** ROlHL-14397-07 Hyperlension-Angiotensin and
prostaglandin pharmacology (animals)
** ROlHL-14775-08 Mechanisms of drug action in vascular
smooth muscle (dog. rabbits)
PHA
ROIHI 15392 06 Autonomic and circulatory «tlioni of
anesthetics (dog. cat. rabbit, monkey)
ROIHL 1544/06 Vascular role ol prostaglandin and cyclic
nucleotides dais)
ROIHL 15696 06 Mechaniim end role of cyclic GMP in
heart (animals)
ROIHI 15698 12 factors aflecling the action ol
anticoagulants (rats, human)
ROIHL 15805 06 Cerebral arterial tone and reactivity
(rabbits)
ROIHL 1598506 Metabolic and hormonal control of
cardiac contraction
ROIHL 15991 05 Evaluation of heart stimulants m sea
anemones
ROIHL 16003 08 Sources and roles of calcrum in smooth
muscle excitation (rats)
ROIHL 16037 06 Molecular properties of cardiac
adrenergic receptors
ROIHL 1631821 Biochemistry and pharmacology of Na K
transport
ROIHL 1632005 Vasoactive peptides which stimulate
smooth muscles (rats, human)
ROIHL 16437 05 Drug treatment ol atherosclerosis
(rabbits, monkeys)
ROlHL-16611 04 Digitalis-receptor of the heart (guinea
pigs, rats)
ROIHL 17401-03 Mechanisms in angiotensin induced
hypertension (cats, dogs)
ROIHL-17451 05 Digitalis effects on cardiac automaticity
mechanisms
ROlHL-17452-04 Depolarization induced cardiac
automaticity (human, animals)
ROIHL 17487-04 Adrenergic vasoregulation interactions in
hypertension (human)
ROIHL 17796-04 Importance of aminosugars in digitalis
activity (cats, rabbits)
' R01HL-18015-03 Pharmacologic studies on vascular
smooth muscle (dogs, rats)
' ROlHL-18148-04 Adrenal catecholamine secretion
■ ROIHL 18199 03 Effects of ions on vascular reactivity
' ROIHL 18259-03 Controlled intratissue release of
prostaglandins
■ R01HL-18260-04
tissue (cattle)
' ROlHL-18598-03
digitalis action
■ ROlHL-18599-02
ionophores (dogs)
■ ROlHL-18601-01
adenosine (rats)
' ROlHL-18607-03 Metabolic and drug studies on
experimental fat embolism (mice)
' ROlHL-18657-03 Pharmacologic studies on neurogenic
digitalis effects (human, cats, dogs)
' R01HL-19044-03 Effect of drugs on development of
cardiac failure (cats)
' ROlHL-19062-03 Pharmacologic control of mast cell
phosphodiesterase (human, rats)
' ROlHL-19129-04
cellular actions
> ROlHL-19325-03
Cyclic nucleotide metabolism in lung
Role of Na, K-ATPase Inhibition on
Cardiovascular pharmacology of
Regulation of neurotransmitter release by
Cardiac glycosides-Mechanisms of
Phosphodiesterase inhibition and muscle
contraction
ROlHL-19517-03 Synthesis of inhibitors for the study of
renal renin (dogs, monkeys)
ROlHL-19653-03 Circulatory system effects of angiotensin
analogs (rats)
R01HL-19772-02 Role of warfarin metabolism in
antivitamin K activity (rats)
ROlHL-19782-02
heart (dogs)
ROlHL-20 194-01
Pharmacologic studies on the ischemic
Brain catecholamines in control of blood
pressure (rats)
ROlHL-20262-02 Cardiac glycosides and the mechanism
of the sodium-potassium pump
ROlHL-20339-02 Vascular alpha-adrenergic receptor
molecular properties
ROlHL-20783-02 Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
ROlHL-20787-02 Thromboxanes and prostaglandins-
Biochemical pharmacology (rabbits, human)
Phospholipids and cardiac receptor
Beta adrenergic catecholamine receptor
Early events following stimulation of
ROlHL-20793-02
function
ROlHL-20859-02
ROlHL-20956-02
human platelets
R23HL-21051-02 Adrenergic receptors and the adenylate
cyclase system (frog RBC)
ROIHL-21052-01 Evaluation of a digitalis therapy advisor
R23HL-21083-02 Pharmacokinetics of digoxin and digitoxin
in humans (rats)
ROlHL-21105-02 Organ specific drugs-Cardiovascular and
renal effects (dogs)
R23HL-21 151-02 Ischemic myocardium-Delivery of blood
flow and drugs (dogs)
R23HL-21196-02 Digitalis induced arrhythmia and NAO KO-
atpase activity (dogs)
ROlHL-21221-02 Clinical antiarrhythmic and
pharmacodynamic studies
ROlHL-21239-02 Isolation and mechanism of action of
thromboxane A2 (human, rabbits)
R23HL-21320-02 Cyclic nucleotide metabolism in vascular
endothelium
(contd)
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Oriented signilicanthi to above subject
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
PHA
ROlHL-21329-02 Beta-receptor regulation and cardiac
sites of drug action (cat, guinea pig, rat)
R0IHL-2I476-02 Anticoagulant drug absorption
interactions (rats)
ROlHL-2167001 Antiarrhythmic studies on 2substitufed
aminoindenes (dogs)
ROlHL-2167201 Antiarrhythmic drug action on VMAZ of
cardiac cells
R01HL-2I742-01 Frequency-dependent drug actions in
cardiac muscle (rabbits)
ROlHL-21799-01 Circumventricular sites of pressor action
of angiotensin II (rats)
ROlHL-21800-01
excretion
R01HL-218I7-01
circulation
ROlHL-21860-18 Factors influencing responses to
adrenergic drugs (guinea pigs, rats, cats)
ROlHL-21995-01 Protein phosphorylation and adrenergic
effects
ROIHL 21996-01 Alteration of digitalis and aldosterone
disposition (rats, rabbits, mice, dogs)
ROlHL-22026-01 Endogenous prostaglandins in asthma
Ion transport in cardiac muscle (dogs.
Angiotensin effects on water intake and
Catecholamines, blood pressure and
** ROlHL-22039-02
rodents, cattle)
** ROlHL-22136-02
" ROlHL-22273-01
(rats)
** R23HL-22309-01
immature dogs
*♦ R23HL-22490-01
heart cells
" ROlHL-22522-01
antagonists
•* ROlHL-22568-01
Histamine and cardiac adenyl cyclase
Oral and lung absorption of nitroglycerin
Cardiovascular pharmacodynamics in
Neurotransmitter receptors of cultured
Cardioselectivity of beta-adrenoceptor
pH effect in heart cells -Influence of
cardiac drugs (tissue culture, rats)
** R23HL-22575-01 Factors modifying cardiac digoxin effects
and content (dogs, cats)
** ROlHL-22685-01 Drugs and excitation-contraction coupling
in heart (animals)
** ROlHL-22718-01 Cardiovascular drug interactions-
Metabolism models (dogs)
** R23HL-22775-01 Muscarinic receptors In the developing
heart (chick embryo)
** R23HL-22882-01 Modulation by disease of effect of
furosemide in man
** ROlHL-23726-01 Treatment of ventricular arrhythmias with
propranolol (human)
" ROlHL-23980-01 Effects of digoxin therapy in newborn
and adult sheep
•* ROlHL-23990-01 Role of phosphoprotein in cardiac
inotropic responses
PHARYNX
SEE ORAL-PHARYNGEAL, PHARYNX
PHENACETIN
SEE PHENYUMIDES, ACETOPHENETIDIN
PHENANTHRO(4,5BCD)FURAN-8,9C-
IMINOETHANO
SEE ALKALOIDS, MORPHINES
PHENELZINE
SEE AZO COMPOUNDS, HYDRAZINES, PHENELZINE
PHENETHYLAMINES
SEE PHENYULKYLAMINES, PHENETHYUMINES (GENERAL)
PHENETHYIBIGUANIDE
SEE GUANIOINES, BIGUANIDES, PHENETHYLBIGUANIDE
PHENETHYLFORMAMIDINYLIMINOUREA
SEE GUANIDINES, BIGUANIDES, PHENETHYLBIGUANIDE
PHENFORMIN
SEE GUANIDINES, BIGUANIDES, PHENETHYLBIGUANIDE
PHENOBARBITAL
SEE PYRIMIDINES, BARBITURATES, PHENOBARBITAL
PHENOLASE
SEE OXYGENASES, MONOPHENOL MONOOXYGENASE
PHENOLIC AMINES, NEOSYNEPHRINE
POlHL-12373-10 0003 Cardiopulmonary physiology and
pathophysiology • Myocardial function in man
POIHL-12373-10 0013 Cardiopulmonary physiology and
pathophysiology - Effects of cardiovascular drugs on left
ventricular function (dogs)
P01HL-I2738-10 0108 Physiologic pharmacology and its
clinical applications - Developmental electrophysiology and
pharmacology (human, animals)
R01HL13375-09 Cellular potential changes causing
cardiac arrhythmias (dogs)
R23HL-22011-01 Adrenergic receptor cyclase system in
sensitized lung (rats, guinea pigs)
ROlHL-22354-01 Alpha-adrenergic effects on heart
metabolism (rats)
ROIHL-22641-01 Ventilation, perfusion, and systemic
arterial reflexes (dogs)
PHENOLIC AMINES, TYRAMINE
ROIHL-05883-18 0003 Reflex control of resistance and
capacitance vessels Cardiac glycosides and sympathetic
nerve terminals in vascular smooth muscle
Regulation of the circulation in
- Mechanism of postural hypotension
404
ROlHL-08359-14 Morphopharmacology of vascular
adrenergic transmission (rabbits, rats)
POlHL-14388-07 0180 Regulation of the circulation in
pathological states - Regulation of cerebral blood flow
(dogs, monkeys)
POlHL-14388-07 0229
pathological states
(human)
ROIHL 17629-03 Developmental aspects of cardiovascular
function (human, cats, rabbits)
R23HL-22728-01 Neural control of renin secretion (dogs)
ROlHL-23209-01 Autonomic receptors of the pulmonary
vasculature (mammals)
PHENOL OXIDASE (MONOPHENOL
MONOOXYGENASE)
SEE OXYGENASES, MONOPHENOL MONOOXYGENASE
PHENONES, PHLORETIN
ROlHL-20725-02 Mechanisms and cellular functions of ion
transport
ROlHL-23183-01 Voltage dependent conductance in
membranes
PHENOTHIAZINES
ROlHL-13909-27 Physiochemistry and immunology of
macromolecules
ROlHL-14820-07 Factors affecting physiology of biological
membranes (human)
PHENOTHIAZINES, CHLORPROMAZINE
ROIHL 13909-27 Physiochemistry and immunology of
macromolecules
ROlHL-15722-06 Hemorrheology studies related to in vivo
blood flow (human)
P50HL-17651-04 0045 Ischemic heart disease specialized
center of research - Peripheral vascular studies-
Pharmacology (dogs, human)
ROlHL-21672-01 Antiarrhythmic drug action on VMAZ of
cardiac cells
ROlHL-227 18-01 Cardiovascular drug interactions-
Metabolism models (dogs)
PHENOTHIAZINES, PERPHENAZINE
POlHL-12738-10 0042 Physiologic pharmacology and its
clinical applications - Centrogenic cardiac arrhythmias
(cats)
PHENOTHIAZINES, PROCLORPERAZINE
POlHL-18576-03 0007 Thrombosis research program
project - Relationships between coagulability and
thrombosis (human, animals)
PHENOTHIAZINES, PROMETHAZINE
R23HL-21203-02 Effect of vasoactive agents on left-to-
right shunts (lambs)
PHENOTYPE
SEE GENETICS, GENES, GENE EXPRESSION
PHENOXYACETIC ACIDS, 2,3-DICHLORO-4-(2-
METHYLBUTYDPHENOXYACETIC ACID
POlHL-06664-17 0039 Cardiopulmonary function In
remediable vascular disease - Transepithellal active
transport and cell volume regulation (frogs)
POlHL-14388-07 0191 Regulation of the circulation in
pathological states - Regulation of chloride transport in
epithelial membranes (turtles)
" POlHL-14388-07 0225 Regulation of the circulation in
pathological states - Release of renal prostaglandins by
saluretic-diuretic agents (dogs)
PHENOXYACETIC ACIDS, HALOFENATE
P50HL-14141-05 0003 SCOR for atherosclerosis In
childhood - Detection of abnormalities in lipid metabolism
(human, rabbits, rats)
PHENOXYBENZAMINE
SEE PHENYLALKYLAMINES, BENZYUMINES,
PHENOXYBENZAMINE
PHENOXYCARBOXYLATES, CLOFIBRATE
ROlHL-06222-18 Clinical and laboratory studies In lipid
metabolism (human, mammals, non-human)
ROlHL-08888-12 Cooperative study of drugs and coronary
heart disease (men)
R01HL-10445-09 Cooperative study of drugs and coronary
heart disease (men)
ROlHL-10705-09 Cooperative study of drugs and coronary
heart disease (men)
ROlHL-10894-12 Intestinal bacteria and steroid
metabolism (human, guinea pigs, rabbits, rats)
ROlHL-11372-08 Cooperative study of drugs and coronary
heart disease (men)
ROlHL-11901-12 0006 Effects of metabolic surgery on
the hyperlipldemias - Drug therapy with Ileal bypass
(rabbits)
ROlHL-12085-10 Lipoprotein-carbohydrate metabolism
(human, rats)
ROlHL-12740-10 Hypocholesterolemic agents-
Stereochemistry (rats)
** ROlHL-13654-08 Antllipemic regimes In peripheral
arteriosclerosis (human)
P50HL-14141-05 0003 SCOR for atherosclerosis in
childhood - Detection of abnormalities in lipid metabolism
(human, rabbits, rats)
PHE
P50HL-14197-07 0006 Support for center of research on
arteriosclerosis - Diets and drugs affecting lipid
metabolism (human)
P50HL-14230-07 0093 A/S SCOR -Lipids, atherosclerosis
and thrombosis - Clinical studies involving cellular lipid
content (human)
P50HL-14236-05 0009 Prevention of premature
arteriosclerosis - Clinical studies on cholesterol metabolism
(human)
P50HL-14237-07 0006 Support for arteriosclerosis center
Drug treatment of familial hyperbetallpoprotelnemia
(human)
ROlHL-15308-07 Assays for peptides of lipoproteins
(human)
ROlHL-15374-03 Cooperative study of drugs and coronary
heart disease (human)
ROlHL-18467-03 Fingertip blood flow in normals and
Raynaud's disease (human)
POlHL-18574-03 0006 Lipoprotein methodology and
biomedical applications - Lipoprotein transformation,
lipolytic enzymes, diet and lipid lowering agents
ROlHL-18607-03 Metabolic and drug studies on
experimental fat embolism (mice)
ROIHL 18887-03 Hypolipidemic drugs -Effects on FFA-
albumin association (human, cattle)
ROlHL-19010-03 Metabolism and cell biology of lung
surfactant system (rabbits, sheep)
ROlHL-19112-03 Atherosclerosis studies (monkeys)
ROlHL-19936-02 Unsaturated fatty acid biosynthesis In
the aorta (rats)
** ROlHL-20909-02 Clofibrate-enhanced lipid oxidation by
peroxisomes (rats)
P50HL-21006 02 0001 Specialized center of research in
arteriosclerosis - Clinic and core program
ROlHL-22607-01 Role of apolipoprotein E in lipoprotein
metabolism (human)
PHENTOLAMINE
SEE IMIDAZOLES, PHENTOLAMINE
PHENYLALANINE
SEE CYCLIC AMINO ACIDS, PHENYLALANINE
PHENYLALKANOLS, PHENYLETHANOL
ROlHL-17487-04 Adrenergic-vasoregulation Interactions In
hypertension (human)
PHENYLALKOXYALKYLAMINES,
DIPHENHYDRAMINE
POlHL-18576-03 0007 Thrombosis research program
project - Relationships between coagulability and
thrombosis (human, animals)
PHENYLALKYLAMINES, AMPHETAMINE
POlHL-12738-10 0065 Physiologic pharmacology and its
clinical applications - Psychotheropeutic drugs and
cardiovascular system (human, rats)
POlHL-14388-07 0180 Regulation of the circulation in
pathological states - Regulation of cerebral blood flow
(dogs, monkeys)
P50HL-15061-07 0005 Response of lung to Injury - Airway
smooth muscle in health and disease (dogs, guinea pigs)
PHENYLALKYLAMINES, D-AMPHETAMINE
ROlHL-18848-03 Etiology and development of congenital
heart disease (dogs, cats)
PHENYLALKYLAMINES, BENZYLAMINES,
BRETYLIUM TOSYLATE
P01HL-I1310-12 0078 Mechanisms of cardiovascular
disease - Ventricular arrhythmias in acute myocardial
infarction (dogs)
ROlHL-14832-06 Myocardial cells-Autonomic and rhythmic
mechanisms (chick embryo, rats)
P50HL-15061-07 0005 Response of lung to Injury - Airway
smooth muscle in health and disease (dogs, guinea pigs)
ROlHL-16076-06 Electrophysiology of fibrillation and
defibrillation (human)
ROlHL-19782-02 Pharmacologic studies on the ischemic
heart (dogs)
ROlHL-21742-01 Frequency-dependent drug actions In
cardiac muscle (rabbits)
ROlHL-22170-01 Factors influencing transmission at
adrenergic synpases
PHENYLALKYLAMINES, BENZYLAMINES,
DIBENAMINE
ROlHL-02835-21 Renal transport carrier for organic
compounds (dogs, rats)
PHENYLALKYLAMINES, BENZYLAMINES,
PHENOXYBENZAMINE
ROlHL-08359-14 Morphopharmacology of vascular
adrenergic transmission (rabbits, rats)
POlHL-10342-13 0019 The Integrated function of
respiration and circulation - Cerebral circulation and
metabolism (dogs)
ROlHL-10914-10 Renal sodium transport in experimental
aldosteronism (dogs)
ROlHL-14713-06
pigs)
R01HL-15758-06
(dogs)
Hypothermia and the heart (bats, guinea
Catecholamine release in the heart
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
(oofltd)
PHE
R01HL'173S&-04 Pulmonary vasculai »d|ustments (n
circuUtory collapse (dogs, rats)
ROIHI 1860/03 Metabolic and druj studies on
expeiimental tat embolism (mice)
ROIHI 1894803 Pulseless (low and citculalofV assistance
(dogs, calves)
R23HL 21203 02 ttlect o( vasoactive agents on left to-
tight shunts (lambs)
R23HL 2230901 Caidiovasculat pharmacodynamics in
Immature dogs
ROIHI 22354 01 Alphaadtenergic effects on heart
metabolism (rats)
PHENYIAIKYIAMINES, CATECHOLAMINES
SEE ALSO CYCLIC AMINO ACIDS, DOPA
SEE ALSO NEUROPHARMACOLOGICAL AGENTS,
SYMPATHOMIMETIC
ROIHL 02063 23 Biochemistry and function of lipids and
cell membranes (human, yeast, animals)
ROIHL 02493 22 Kidney (unction in experimental heart
failure (dogs, rats)
R01HL03290-22 Controls of cardiac and vascular smooth
muscles (cats, rats, dogs)
ROlHL-05806-18 Analysis of antiarrhythmic agents (dogs,
rabbits)
•* R01HL0587518 Pathologic metabolic and physiologic
studies of heart (human, dogs, cats)
P01HL0628518 0186 Cardiovascular-respiratory
physiology and biochemistry Leukocyte hormone receptors
and cyclic nucleotides (tissue culture)
POlHL-06308-18 0040 Mechanisms and therapy of
circulatory disease Metabolism and fatty acid utilization-
Heart electrical stability (rats, dogs)
POlHL-06370-17 0015 Cardiopulmonary and renal
pathology research center - Pathogenesis of chemically
induced tissue injury (rats)
ROlHL-06736-18 Biogenic-mechanical factors in
microcirculation (rats, gerbils)
POlHL-06835-17 0030 Cardiovascular disease - Synthesis
and pharmacology of angiotensin antagonists (rats, cats)
POlHL-06835-17 0031 Cardiovascular disease - Synthesis
of potent antagonist of pressor action of angiotensin II
(animals)
POlHL-06835-17 0037 Cardiovascular disease - Cardiac
hypertrophy in spontaneously hypertensive rat
POlHL-06835-17 0038 Cardiovascular disease - Effect of
chronic administration of angiotensin antagonist (rats)
POlHL-06835-17 0040 Cardiovascular disease - Benign
and malignant phase of renal hypertension (dogs)
** POlHL-07896-15 0052 Environmental biomedical research
program - Effects of hypoxia on cerebral function
R01HL08359-14 Morphopharmacology of vascular
adrenergic transmission (rabbits, rats)
POlHL-08682-15 0006 Regulation of the cardiovascular
system ■ Cardiovascular studies of mammalian hibernators
(sciuromorpha)
POlHL-08682-15 0011 Regulation of the cardiovascular
system ■ Histochemistry and ultrastructure of heart
innervation (dogs, ground squirrels)
POlHL-08682-15 0033 Regulation of the cardiovascular
system - Functional and anatomical relations during
cardiac re-innervation (dog)
ROlHL-09489-13 Myocardial lipid metabolism and
regulation (rats)
ROlHL-09914-13 The myocardium in diabetes mellitus
(dogs, monkeys)
POlHL-11307-12 0003 Biophysical studies in pediatric
cardiology - Cellular biophysics (animals)
POlHL-1 1351-12 0013 Cellular and molecular
mechanisms of myocardial function - Ion exchange in the
perfused septum high-resolution technique (rabbits, rats)
** POlHL-1 1414-11 0028 Thrombosis and atherosclerosis
program - Catecholamine metabolism in the lung (rat)
ROlHL-11614-11 Trace elements in nutrition (chickens.
rats, human)
POlHL-1 1678-11 0059 Cardiovascular dynamics and their
control - Basic hemodynamics (dogs, rats)
ROlHL-11802-10 Cardiovascular surgical research (dogs,
sheep, swine, cats, monkeys)
ROlHL-1 1906-11 Comparative study of heart function
(cats, rats, hedgehogs, squirrels)
R01HL-12085-10 Lipoprotein-carbohydrate metabolism
(human, rats)
POlHL-12157-11 0049 Functions and mechanisms of cell
membrane ion transport - Ouabain-insensitive cation
transport in duck red cells
P01HL-12373-10 0002 Cardiopulmonary physiology and
pathophysiology - Determinants of performance of the
whole heart (dogs)
POlHL-12373-10 0012 Cardiopulmonary physiology and
pathophysiology - Biochemistry of the sympathetic nervous
system (rats, rabbits, pigeons)
ROlHL-12421-10 Pathophysiology of circulatory shock
(dogs, baboons)
** ROlHL-12648-09 Catecholamine metabolism in
hypertensive diseases (human)
POlHL-12738-10 0076 Physiologic pharmacology and its
clinical applications - Pediatric cardiac electrophysiology
and pharmacology (human, dogs)
POlHL-12738-10 0080 Physiologic pharmacology and its
clinical applications - Electrophysiology of cardiac muscle
In the mitral valve (monkeys)
405
POIHI 12/38 10 010/ Physiologic phaimacology and ih
clinical applications Blood iupcrfused caidiac fibers
(dogs)
POIHL 12738 10 0108 Physiologic pharmacology and its
clinical applications Developmental electrophysiology and
pharmacology (human, animals)
POIHL 12/38 10 0136 Physiologic pharmacology and its
clinical applications
ROIHL 12/7408 Ionic coupling in activation of cardiac
muscle (frogs, guinea pigs)
ROIHL 1282/ 08 Regulation of sodium excretion (dogs,
rats)
ROIHL 12990 09 Control of antidiuretic hormone secretion
and metabolism (dogs, rats, rabbits)
ROIHL 13036 08 Coronary thrombosis Effects on
myocardium and in vivo detection (dogs, monkeys)
POIHL 13108-09 0008 Clinical heart transplantation
Physiology and pharmacology of the transplanted human
heart
POIHL 13108-09 0019 Clinical heart transplantation
Etfect of autonomic nervous system on arrhythmias
(human)
POIHL 1310809 0023 Clinical heart transplantation
Adaptive mechanisms of the denervated heart (human)
ROIHL 13257-09 Inhalation anesthesia on myocardial
metabolism (dogs, swine, human)
ROlHL-13375-09 Cellular potential changes causing
cardiac arrhythmias (dogs)
ROlHL-13666-06 Pharmacology of genesis of cardiac
rhythmicity (rats, cats)
RO1HL1371508 Myocardial adenyl cyclase (rats)
ROlHL-14092-07 Homeostatic regulation of plasma choline
(rats, dogs, chickens)
■* P50HL-141 5908 0018 Specialized center of research in
hypertension - Sympathetic nervous system in hypertension
(rats)
P50HL-14159-08 0022 Specialized center of research in
hypertension - Core laboratory
ROlHL-14306-07 Quantification of arterial pressure control
(dogs)
•• P01HL14388-07 0151 Regulation of the circulation in
pathological states - Catecholamine release in potassium
ion-free contractures in the caudal artery
POlHL-14388-07 0180 Regulation of the circulation in
pathological states - Regulation of cerebral blood flow
(dogs, monkeys)
POlHL-14388-07 0193 Regulation of the circulation in
pathological states - Ontogenesis of central nervous system
amines in hypertension (rats)
POlHL-14388-07 0194 Regulation of the circulation in
pathological states - Dopamine-beta-hydroxylase localization
and release in hypertension
POlHL-14388-07 0198 Regulation of the circulation in
pathological states - Humoral factors in vascular reactivity
in spontaneously hypertensive rats
POlHL-14388-07 0212 Regulation of the circulation in
pathological states - Role of dopamine in autonomic
activity
POlHL-14388-07 0213 Regulation of the circulation in
pathological states - Regulation of the heart and peripheral
circulation in heart failure
POlHL-14388-07 0215 Regulation of the circulation in
pathological states - Left ventricle model in
pathophysiologic states
POlHL-14388-07 0229 Regulation of the circulation in
pathological states - Mechanism of postural hypotension
(human)
ROlHL-14397-07 Hypertension -Angiotensin and
prostaglandin pharmacology (animals)
ROlHL-14461-08 Cardiac metabolism in heart failure
(rats)
ROlHL-14526-07 Oral contraceptives and hypertension
(rats)
** ROlHL-14693-07 Survival value of physiological responses
to hypoxia (dogs)
ROlHL-147 17-06 Hemodynamics and heart structure-
Ventricular overload (dogs)
ROlHL-14899-07 Mechanism and prevention of cardiac
arrhythmias (dogs)
ROlHL-15002-07 Biochemical pharmacology of guanylate
cyclase in lung (cattle, rats)
POlHL-15194-07 0004 Pathophysiology of
cardiopulmonary dysfunction - Specialized electrophysiology
fibers-Electrogenic basis of glycosides (mammals)
ROlHL-15307-06 Central nervous control ot renin and
blood pressure (dogs)
ROlHL-15444-06 Neonatal development of adrenergic
receptor mechanisms (pigs)
ROlHL-15580-06 Humoral control of pulmonary and
systemic circulation (animals)
** ROlHL-15677-06 Autonomic nervous system function in
bronchial asthma (human, guinea pig, rabbit)
ROlHL-15681-06 Coronary flow studies of partially
obstructed vessels (dogs)
** ROlHL-15758-06 Catecholamine release in the heart
(dogs)
ROlHL-15764-05 CAMP dependent protein kinase m
cardiac contraction (dogs)
R01HL15805-06 Cerebral arterial tone and reactivity
(rabbits)
ROlHL-15808-06 Role ot angiotensinogen in hypertension
and stroke (human, rabbits)
PHI
ROIHI 1603/ 06 Molecular piopertie* ol cardiac
adieneigic leccptois
POIHI 1611/ O'j 0005 Ion movements and membranet in
cardiovascular tonliol PropertiM of nollted cell
membranes (rabbil%, cats)
ROIHI 16135 05 Mechanisms of cardiac autoihythmicity
(dogs, bats)
POIHI 1613/05 0013 Alveolar biology Development and
pathology of surfactant formation of alveolar (rabbits,
sheep)
ROIHL 16152 06 Electrophysiology of neonatal to adult
heart (cats, frogs, guinea pigs)
ROIHI 1645403 Vascular muscle reactivity in
hypertension (human, rats)
ROIHL 1647405 Antibiotic ion interactions (model
membranes)
ROIHL 16/14 05 Endothelial cell communication in
homeostasis (human, mammals)
ROIHL 1676804 The sympathetic nervous system and the
arterial wall (rabbits, pigeons)
ROIHL 17335 05 Contractile properties of hypertensive
arterioles (rats)
ROIHL 17355 04 Pulmonary vascular ad|ustments in
circulatory collapse (dogs, rats)
POIHL 17382 05 0001 Chemical mediators of acute
pulmonary disorders - Chemical mediators and respiratory
mechanics in humans
ROIHL 1/40303 Metabolic control of cardiac output
(dogs)
ROlHL-17452-04 Depolarization induced cardiac
automaticity (human, animals)
ROlHL-17487-04 Adienergic-vasoregulation interactions in
hypertension (human)
ROlHL-17629-03 Developmental aspects of cardiovascular
function (human, cats, rabbits)
* ROlHL-17706-04 Psychosocial hypertension,
catecholamines and drugs (mice)
ROlHL-17799-02 The presence and significance of heart
acetylcholine (cats)
POlHL-17813-04 0008 Lung disease and the oxygenation
of blood and tissue - Pulmonary regulation of systemic
blood pressure (human, rabbits, rats)
ROlHL-17847-04 Cardiovascular and renal functions of
marmots
ROIHL- 17958-04 Circulatory effects of operant
cardiovascular control (baboons)
ROlHL-18015-03 Pharmacologic studies on vascular
smooth muscle (dogs, rats)
** ROlHL-18050-04 Mechanisms of cardiovascular
teratogencsis (chick embryo) k embryo)
** ROlHL-18095-04 Human dopamine-beta-hydroxylase (also
cattle)
ROlHL-18096-04 Vasoactive agents in splanchnic viscera
(primates, dogs)
** ROlHL-18148-04 Adrenal catecholamine secretion
ROlHL-18176-02 Effect of thyroid hormone on cultured
cardiac cells (rats)
ROlHL-18185-04 Cardiac glycosides and diuretics -Role of
NaO pump (dogs)
P50HL-18318-03 0001 Pathogenesis and complications ot
hypertension - Core clinical program
P50HL-18318-03 0003 Pathogenesis and complications of
hypertension - Core biochemical laboratory
P50HL-18318-03 0015 Pathogenesis and complications of
hypertension ■ Cultured smooth muscle cells and
microvessel metabolism (mammals)
•• P50HL-18323-04 0046 SCOR hypertension center -
Coronary artery bypass surgery-Associated hypertension
(human)
ROlHL-18371-03 Pulmonary hypertension and ventilation
pathophysiology (dogs)
ROlHL-18517-03 Intrinsic innervation of the heart (dogs)
ROlHL-18599-02 Cardiovascular pharmacology of
ionophores (dogs)
ROlHL-18601-01 Regulation of neurotransmitter release by
adenosine (rats)
ROlHL-18624-03 Study of kinins in hypertension and other
diseases (human)
ROlHL-18705-03 Regulation of plasma triglyceride
metabolism (rats)
POlHL-18708-03 0010 Oxygen, energy and contractility in
cardiac tissue - Tissue oxygen utilization (rats, dogs)
ROlHL-18749-03 Ventricular mechanics in the overloaded
heart (dogs)
ROlHL-18762-03 Post-traumatic pulmonary insufficiency
(dogs)
R01HL-18824-03 Mechanisms of heart failure in
myopathic hamster
ROlHL-18907-03 Objective evaluation early after Ml and
heart surgery (human)
M POlHL-18974-03 Experimental neurogenic hypertension
program
POlHL-18974-03 0001 Experimental neurogenic
hypertension program - Central neural systems regulating
arterial pressure (rabbits)
POlHL-18974-03 0008 Experimental neurogenic
hypertension program - Monoamines and hypertension
(rats)
** POlHL-18974-03 0009 Experimental neurogenic
hypertension program - Biochemistry of brain tyrosine
hydroxylase (rats)
(contd)
•Excludes routine methodology OR covers only general proiects which preclude
••Oriented significantly to above subject.
indexing at the specific level.
M Grant has subprajects describing specific research aspects.
See Appendix for investigator's name and grant number.
w:mm,
PHE
** POlHL-18974-03 0012 Experimental neurogenic
hypertension program - Immunohistochemistry of central
monoamine neurons (rats)
ROlHL-18976-03 Blood pressure control-Relation to
behavioral stress (human, dog)
** ROlHL-18995-04 Cardiovascular determinants of
catecholamine release (dogs)
ROlHL-19027-03 Calcium and cyclic AMP in causation of
hypertension (rats)
" ROlHL-19057-03 Catecholamines and cyclic AMP in
cardiovascular system (rats, dogs)
ROlHL-19063-03 Cholesterol and lipoprotein metabolism
(rat hepatocytes)
R01HL1911502 Hormonal control of tracheobronchial
cyclic AMP (rats, guinea pigs)
** R01HL19127 03 Synthesis of molecules for myocardial
imaging (rats)
R01HL19134-04 Angiotensin, prostaglandins, adrenergic
interactions (rats, rabbits)
R01HL19182-03 Surgical aspects of myocardial
hypertrophy (dogs)
POlHL-1924202 0004 Study of vascular smooth muscle -
Cyclic nucleotide metabolism in smooth muscle cultures
(human, rats)
P50HL-1936202 0010 A/S SCOR -Atherosclerosis in
nonhuman primates - Antihypertensive therapy-
Atherogenesis in experimental hypertension (baboon)
ROlHL-1939403 Biochemistry and regulation of taurine in
the heart (rats, guinea pigs, cats)
R01HL-1939803 Regional conduction abnormalities and
arrhythmias (dogs)
** ROlHL-1942303 Catecholamine action on Ihe heart (cats.
rats)
" POlHL-19717-02 0013 Response of the lung to injury ■
Handling of biologically active substances by the diseased
lung (guinea pigs)
** POlHL-1971702 0037 Response of the lung to injury -
Catecholamines, prostaglandins and nucleotides in
pulmonary function (animals)
** ROlHL-1987003 Hypertensive progeny-Physical and
humoral precursor search
ROlHL-20184-02 Desensitization of tracheal muscle to
isoproterenol (rats, rabbits)
♦* ROlHL-20194-01 Brain catecholamines in control of blood
pressure (rats)
ROlHL-20206-02 Carbohydrates-nucleotides and adrenergic
Interactions (rabbits, cats, rats)
ROlHL-2028602 Interventions to improve cardiac function
in ischemia (dogs)
ROlHL-20339-02 Vascular alpha-adrenergic receptor
molecular properties
ROlHL-2047603 Effects of diabetes on cardiac
performance (rat)
ROlHL-20542-03 Regional hemodynamics in spontaneous
hypertension (rats)
POlHL-20552-02 0004 The development and regression of
cardiac hypertrophy - Ventricular function in experimentally
induced hypertrophy (hogs, sheep, baboons)
R01H1.-20564-02 Pathogenesis of peripheral arterial
disease (rats, rabbits)
POlHL-20581-01 0003 Vascular neuroeffector
mechanisms in health and disease - Cerebrovascular
neuroeffector characteristics (animals)
POlHL-20581-01 0006 Vascular neuroeffector
mechanisms in health and disease - Neuroeffector
mechanism in arteries and veins in hypertension (human)
ROlHL-20604-03 Sympathectomy -Cardiovascular and
molecular pharmacology (animals)
ROlHL-2061002 Nerve grovrth factor and obstructive
cardiomyopathy (dogs)
ROlHL-20719-02 Cold induced pulmonary hypertension
(cattle)
ROIHL-20768-02 Mechanisms of circulatory regulation in
heart failure (guinea pigs)
ROlHL-20782-01 Coronary flow regulation by adenosine
(rats, dogs)
ROlHL-20783-02 Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
** ROlHL-20859-02 Beta adrenergic catecholamine receptor
ROIHL-20956-02 Early events folloviing stimulation of
human platelets
R23HL-2105I-02 Adrenergic receptors and the adenylate
cyclase system (frog RBC)
R23HL-21 116-02 Mechanisms of membrane and tissue
damage in lung (dogs, rabbits)
ROlHL-2 1158-02 Cardiac receptors viith vagal C-fiber
afferents (cats)
ROlHL-21210-01 Acute renal failure following cardiac
surgery (human)
R23HL-21234-02 The regulation of cardiac hypertrophy
(rabbits)
ROlHL-21329-02 Beta-receptor regulation and cardiac
sites of drug action (cat, guinea pig. rat)
ROlHL-21578-01 Effect of exercise upon the hypertensive
adolescent
ROlHL-21670-01 Antiarrhythmic studies on 2-substituted
aminolndenes (dogi)
'* ROlHL-21817-01 Catacholtmlnas, blood pressure and
circulation
R01HL-21893-C1 Blood voluma distribution In hypertanslon
(human)
'* R23HL-21914-01 Studiss of vasomotor control (rati)
406
R23HL-21973-01 Catecholamine metabolism and the heart
(human, guinea pigs)
ROlHL-21995-01 Protein phosphorylation and adrenergic
effects
ROlHL-22069-02 Experimental renal arterial hypertension
(dogs)
ROlHL-22080-01 Phosphorus NMR studies on cardiac
tissue (rats, rabbits)
ROlHL-22101-02 Hormone-substrate interaction in diabetic
myocyte (dogs, rats)
ROlHL-222 15-01 Effects of exercise-training in ischemic
heart disease (human)
ROlHL-22223-01 The cardiopulmonary junction (dogs,
models)
ROlHL-22226-01 Autonomic nervous elements in the
developing heart (rabbits)
ROlHL-22235-01 Mechanism of cardiac pacemaking
(rabbits)
ROlHL-22244-01 Cardiopulmonary bypass and the
vascular endothelium (dogs)
ROlHL-22298-02 Origins of hypertension (human)
** ROlHL-22306-01 Renal catecholamines- Pathophysiology
of hypertension (dogs)
" ROlHL-22354-01 Alpha-adrenergic effects on heart
metabolism (rats)
ROIHL 22415-01 Mechanisms responsible for disease
severity in asthma (human)
ROlHL-22426-01 Initiation of the heartbeat-A voltage-
clamp study (bullfrogs, rabbits)
ROlHL-22573-01 Treatment of post surgical
vasoconstriction (dogs, monkeys, human, rats)
ROlHL-22603-01 Trace metals, vascular activity and
hypertension (rats)
ROlHL-22617-01 Angiotensin, hypertension and the CNS
(sheep)
POlHL-22619-01 0010 Cellular mechanisms of heart
failure - Mitochondria in heart and smooth muscle (rabbits,
rats, dogs)
** ROlHL-22828-01 Adenosine and catecholamine interaction
in the heart (rats)
** ROlHL-22873-01 Adrenoceptor interconversion and
hormone homeostasis
R23HL-22959-01 Heart development in inherited
cardiomyopathy (hamsters)
R23HL-22972-01 Microcirculatoiy function in hypotension
(rats, hamsters)
** ROlHL-22977-01 Role of vasoconstrictor mechanisms in
heart failure (human, dogs)
R01HL-23201-01 Mechanisms of hypertension (human,
rats)
ROlHL-23587-01 Phosphorylation of myocardial protein
(guinea pigs)
ROlHL-23599-01 Mechanisms of ischemic rhythm
disorders (dogs)
R01HL-23603-01 Morphogenesis of hypertensive vascular
disease (rats)
PHENYLALKYLAMINES, CATECHOLAMINES,
DOBUTAMINE
ROlHL-12322-10 Extrinsic factors influencing myocardial
performance (dogs, swine)
ROlHL-12777-09 Mechanisms in cardiac performance
(dogs, human)
R23HL-22309-01 Cardiovascular pharmacodynamics in
immature dogs
PHENYLALKYLAMINES, CATECHOLAMINES,
DOPAMINE
POlHL-06285-18 0182 Cardiovascular-respiratory
physiology and biochemistry - Structure and function of
vascular chemoreceptors (cats, rats)
POlHL-10436-13 0001 A multidisciplinary study of
congenital heart disease - Assessment of the outlook for
children with congenital heart disease
R01HL12648-09 Catecholamine metabolism in
hypertensive diseases (human)
POlHL-12738-10 0094 Physiologic pharmacology and its
clinical applications - Ventricular function and structure
(human, dogs)
POlHL-12738-10 0133 Physiologic pharmacology and its
clinical applications - Pharmacologic antagonism of beta-
adrenergic blockade (dogs)
P01HL-14388-07 0193 Regulation of the circulation in
pathological states - Ontogenesis of central nervous system
amines in hypertension (rats)
** P01HL-14388-07 0212 Regulation of the circulation in
pathological states - Role of dopamine in autonomic
activity
P01HL-14388-07 0220 Regulation of the circulation in
pathological states - Pharmacology of the coronary
circulation In man
ROlHL-14693-07 Survival value of physiological responses
to hypoxia (dogs)
POlHL-14985-07 0010 Adaptation to hypoxia - Pulmonary
mast cell (animals)
P50HL-15061-07 0005 Response of lung to Injury - Almtay
smooth muscle In health and disease (dogs, guinea pigs)
ROlHL-15607-06 Physiological control of splanchnic
circulation (dogs)
R01HL-16066-0S Studies on neurogenic control of tha
circulation (human, dogs)
ROlHL-17487-04 Adrenerglc-vasoregulatlon Intaractlons In
hypertension (human)
PHE
ROlHl-18084-03 Artificial heart and related problems
(calves)
P50HL-18323-04 0041 SCOR hypertension center -
Measurement of sympathetic response in hypertensive
patients
ROlHL-18371-03 Pulmonary hypertension and ventilation
pathophysiology (dogs)
ROlHL-18599-02 Cardiovascular pharmacology of
ionophores (dogs)
** ROlHL-19057-03 Catecholamines and cyclic AMP in
cardiovascular system (rats, dogs)
R23HL-22309-01 Cardiovascular pharmacodynamics in
immature dogs
ROlHL-22568-01 pH effect in heart cells-Influence of
cardiac drugs (tissue culture, rats)
R23HL-22669-01 Cardiovascular effects from visceral
afferents (dogs)
ROIHL 22836-01 The spontaneously hypertensive kidney
(rats)
" ROlHL-23614-02 Pharmacology of relaxation in smooth
muscle (mollusks)
ROIHL 23653-01 Protection of the ischemic myocardium
(dogs)
PHENYLALKYLAMINES, CATECHOLAMINES,
EPINEPHRINE
SEE ALSO NEUROTRANSMIHERS RECEPTORS. ADRENERGIC
RECEPTORS
ROIHL 03181-21 0027 Hemodynamics as applied to
surgical problems - Hemodynamic studies of the Gl tract
(dogs)
ROlHL-03290-22 Controls of cardiac and vascular smooth
muscles (cats, rats, dogs)
ROlHL-09914-13 The myocardium in diabetes mellltus
(dogs, monkeys)
ROIHL 12648-09 Catecholamine metabolism in
hypertensive diseases (human)
POIHL 12738 10 0094 Physiologic pharmacology and its
clinical applications - Ventricular function and structure
(human, dogs)
POlHL-12738-10 0108
clinical applications
Physiologic pharmacology and its
Developmental electrophysiology and
pharmacology (human, animals)
POlHL-12738-10 0133 Physiologic pharmacology and its
clinical applications - Pharmacologic antagonism of beta-
adrenergic blockade (dogs)
POIHL 12738-10 0134 Physiologic pharmacology and its
clinical applications - Adenylate cyclase and cAMP
phosphodiesterase in cardiac development (dogs)
ROlHL-12827-08 Regulation of sodium excretion (dogs,
rats)
ROlHL-1330608 Pharmacological control of cardiac
membrane currents (cattle, rabbits)
ROlHL-13870-09 Control of myocardial sarcotubular
calcium stores (dogs)
POlHL-14388-07 0163 Regulation of the circulation in
pathological states - Adrenergic receptors in coronary
vessels (dogs)
POlHL-14388-07 0193
pathological states
Regulation of the circulation In
Ontogenesis of central nervous systeni
amines in hypertension (rats)
POlHL-14388-07 0230 Regulation of the circulation in
pathological states - Effects of indomethacin in patients
with carcinoid syndrome
POlHL-14388-07 0231 Regulation of the circulation in
pathological states - Mechansim of cutaneous
vasodilatation in Paget's disease of bone
ROlHL-14903-07 A new index of cardiac contractility
(human, dogs, baboons)
ROlHL-15567-05 Cardiovascular phosphoinosltide
metabolism (rats)
R01HL16037-06 Molecular properties of cardiac
adrenergic receptors
ROlHL-16152-06 Electrophysiology of neonatal to adult
heart (cats, frogs, guinea pigs)
ROlHL-16254-05 Pathogenesis of bubble and ck)t
formation (fish)
ROlHL-17954-03 Narcotics and the circulation (human,
dogs, pigs, monkeys)
ROIHL- 18080-03 Extrinsic control of intestinal
microcirculation (dogs)
ROlHL-18148-04 Adrenal catecholamine secretion
P50HL-18318-03 0011 Pathogenesis and complications of
hypertension - Adrenergic function-Renin and
mineralocorticoid activity (human)
P50HL-18323-04 0041 SCOR hypertension center -
Measurement of sympathetic response in hypertensive
patients
P50HL- 18828-03 0004 Specialized center of research in
thrombosis - Membrane changes in platelet physiology-Role
of complement (mice, human)
R01HL1899504 Cardiovascular determinants of
catecholamine release (dogs)
ROlHL-19010-03 Metabolism and cell biology of lung
surfactant system (rabbits, sheep)
ROlHL-19039-03 Circulation studies by one vs two circuit
model (dogs)
R01HL19451-03 0003 Functional charactariitlci of tha
left heart ■ Left ventricular segmental contraction (human,
dogs)
ROlHL-19532-01 Oxygan toxicity In tha rad call (human)
'EicludM routine methodokigy OR coven only leneril projecti which pracluda Indexing at the ipaclfic level.
"Ortentad tiinlflcintly to above lubjaot.
M Grant has subprojectt dtscrtbing specific research aiptcts.
See Appendix for Inveitlgitor'i name and grant number.
v^SSSSS;^
PNI
POIHI' 197 17-02 0007 Responst ol the lung to inluiy
Ctllulii lavd studlts ol piostaglandin liKe molecules
(cettle)
ROIHI 2033902 Vascular alpha adienergic leceptoi
molecular properties
ROIHL 20S17 03 Diabetes, somatotropin, lector VIM and
atherosclerosis (human, animal)
ROIHL 20783 02 Airxay reactivity Badrenocoplors and
pivstaglandins (guinea pigs)
R23HL'2IOSI'02 Adrenergic receptors and the adenylate
cyclase system (Irog RBC)
ROIHL'21318'02 Mechanisms ol emotions' asthma
trigiering ellect (human)
R0IHL21S74'01 Automaticity ol AV node and its adjacent
tissues (dogs)
ROlHl-2181202 Actions ol drugs and ions on cardiac
membranes (rabbits, guinea pigs)
R01HL'218I7-01 Catecholamines, blood pressure and
circulation
ROIHL 22065-01 Intractability, medication, and coping
styles in asthma (human)
R23HL-2230901 Cardiovascular pharmacodynamics in
immature dogs
ROlHL-22354-01 Alpha-adrenergic ellects on heart
metabolism (rats)
ROIHI.-2242e-01 Initiation ol the heartbeat -A voltage-
clamp study (bullirogs. rabbits)
• ROlHL-22514-01 Behavior patterns, stress, and
catecholamines
ROlHL-22522 01
antagonists
ROlHL-22569-02
Cardioselectivity ol beta-adrenoceptor
Intestinal secretion -Capillary and tissue
lorces (dogs, cats)
R23HL-2266901 Cardiovascular eltects Irom visceral
aHerents (dogs)
PHENYLALKYIAMINES, CATECHOLAMINES, L-
HYDROXYDOPAMINE
R01HL03181-21 0025 Hemodynamics as applied to
surgical problems - Vascular stenosis (dogs)
R01HL10942-09 Study ol genetic hypertension in rats
R01HL12827-08 Regulation ol sodium excretion (dogs,
rats)
P01HL14388-07 0179 Regulation ol the circulation in
pathological states - Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
ROlHL-1471306 Hypothermia and the heart (bats, guinea
pigs)
ROlHL-14717-06 Hemodynamics and heart structure-
Ventricular overload (dogs)
P01HL14985-07 0007 Adaptation to hypoxia ■ Control ol
pulmonary circulation, histamine and the sympathetics
(animals)
R01HL-I5580-06 Humoral control ol pulmonary and
systemic circulation (animals)
ROlHL-16768-04 The sympathetic nervous system and the
arterial wall (rabbits, pigeons)
ROIHL- 18340-04 Electron microscopy ol the
juxtaglomerular apparatus (rats)
POIHL-18974-03 0008 Experimental neurogenic
hypertension program - Monoamines and hypertension
(rats)
ROIHL-19394-03 Biochemistry and regulation ol taurine in
the heart (rats, guinea pigs, cats)
PHENYLALKYIAMINES, CATECHOLAMINES,
ISOPROTERENOL
R01HL-01015-27 Hypertension and left ventricular
hypertrophy (dogs)
ROlHL-05806-18 Analysis ol antiarrhythmic agents (dogs.
rabbits)
POlHL-06285-18 0186 Cardiovascular-respiratory
physiology and biochemistry - Leukocyte hormone receptors
and cyclic nucleotides (tissue culture)
POlHL-06308-18 0039 Mechanisms and therapy ol
circulatory disease - ANS in regulation ol electrophysiology-
Role ol cyclic nulceotides (animals)
POlHL-06314-17 0054 Immunologic mechanisms in
cardiovascular disease - Physiology ol cell communications
(mice, Irogs, guinea pigs)
POlHL-10342-13 0019 The integrated lunction ol
respiration and circulation - Cerebral circulation and
metabolism (dogs)
POlHL-1 1310-12 0062 Mechanisms ol cardiovascular
disease - Myocardial depressant tactor in postoperative
cardiac dyslunction (human, dogs)
POlHL-1 1310-12 0079 Mechanisms ol cardiovascular
disease - Electrophysiological studies ol complete heart
block (human)
POlHL-1 1678-11 0059 Cardiovascular dynamics and their
control ■ Basic hemodynamics (dogs, rats)
POlHL-12373-10 0003 Cardiopulmonary physiology and
pathophysiology - Myocardial lunction in man
POlHL-12373-10 0012 Cardiopulmonary physiology and
pathophysiology ■ Biochemistry ol the sympathetic nervous
system (rats, rabbits, pigeons)
POlHL-12738-10 0094 Physiologic pharmacology and Its
clinical applications - Ventricular lunction and structure
(human, dogi)
POlHL-12738-10 0108
(llnlcil appllcttioni -
407
POIHL 12738 10 0133 Physiologic pharmacology and its
clinical applications Pharmacologic antagonism ol beta
adrenergic blockade (dogs)
POIHI 1310809 0017 Clinical heart transplantation
Electrophysiology ol the transplanted denervated human
heart
ROIHL 1337509 Cellular potential changes causing
cardiac arrhythmias (dogs)
P50HL 1415307 0011 lohns Hopkins Lung Center
Chronic diseases ol airways Allergy, airways reactivity
and asthma in human ragweed allergy
POIHL 1438807 0163 Regulation ol the circulation in
pathological states Adrenergic receptors m coronary
vessels (dogs)
POIHL 1438807 0215 Regulation ol the circulation in
pathological slates Lett ventricle model in
pathophysiologic states
ROIHL 1454506 Mechanics ol compensatory ventricular
hypertrophy (dogs)
ROIHL 14713-06 Hypothermia and the heart (bats, guinea
pigs)
ROIHL 14903-07 A new index ol cardiac contractility
(human, dogs, baboons)
ROIHL 15985-06 Metabolic and hormonal control ol
cardiac contraction
R01HL16236-04 Detailed characletistics ol coronary blood
How (horses, dogs, calves)
R01HL16463-05 Localization ol airways obstruction and
responses
ROlHL-167 10-03 Myocardial subcellular localization ol
calcium (dogs)
ROlHL-16760-05 Dynamic control ol coronary blood How
(dogs)
POlHL-16910-05 0002 Regulation ol the peripheral
circulation - Coronary circulation (dogs)
POlHL-17382-05 0001 Chemical mediators ol acute
pulmonary disorders - Chemical mediators and respiratory
mechanics in humans
POlHL-17382-05 0002 Chemical mediators ol acute
pulmonary disorders - Chemical mediators and respiratory
mechanics in guinea pigs
ROlHL-17459-03 Myocardial ischemia (dogs)
ROlHL-17689-06 Neurophysiologic studies ol respiratory
control (cats)
POlHL-17731-04 0006 Physiological basis ol pulmonary
disease - Ventilation-perlusion ratios (human, dogs)
ROlHL-17873-04
asthma (human)
ROlHL-18084-03
(calves)
ROlHL-18371-03 Pulmonary hypertension and ventilation
pathophysiology (dogs)
ROlHL-18599-02 Cardiovascular pharmacology ol
ionophores (dogs)
ROlHL-19057-03 Catecholamines and cyclic AMP in
cardiovascular system (rats, dogs)
P50HL-191 70-02 0007 Harvard pulmonary SCOR-Chronic
diseases ol the airways - Therapy ellect on airway
obstruction in acute asthma (human)
ROlHL-19378-03 Relation ol mitochondrial changes to
cardiac lailure (dogs, rats)
ROlHL-19394-03 Biochemistry and regulation ol taurine in
the heart (rats, guinea pigs, cats)
ROlHL-19423-03 Catecholamine action on the heart (cats,
rats)
ROlHL-19451-03 0001 Functional characteristics ol the
left heart - Ventricular perlormance using epicardial
radiopaque markers (human)
'* ROlHL-20184-02 Desensitization ol tracheal muscle to
isoproterenol (rats, rabbits)
Pathophysiology ol exercise-induced
Artilicial heart and related problems
Role ol taurine in the heart (dogs, rats.
Vascular control in experimental diabetes
pharmacology (human, animals)
Physiologic pharmacology and its
Developmental electrophysiology and
R01HL-202 11-02
mice)
ROlHL-20399-03
mellitus (dog)
ROlHL-20542-03 Regional hemodynamics in spontaneous
hypertension (rats)
ROlHL-20783-02 Airway reactivity-6-adrenoceptors and
prostaglandins (guinea pigs)
ROlHL-20793-02 Phospholipids and cardiac receptor
lunction
ROlHL-20859-02 Beta adrenergic catecholamine receptor
ROlHL-21329-02 Beta-receptor regulation and cardiac
sites ol drug action (cat. guinea pig. rat)
R23HL-21539-02 Mechanical properties ol isolated small
bronchioles (rabbits)
POlHL-21584-02 0006 Respiratory mechanics in normal
and abnormal states - Respiratory mechanics in health and
disease (human, pigs)
R23HL-21973-01 Catecholamine metabolism and the heart
(human, guinea pigs)
R23HL-220 11-01 Adrenergic receptor cyclase system in
sensitized lung (rats, guinea pigs)
ROlHL-22065-01 Intractability, medication, and coping
styles in asthma (human)
ROlHL-22137-02 Structure-function pathology of isolated
heart cells (mice, rats)
ROlHL-22306-01 Renal catecholamines- Pathophysiology
of hypertension (dogs)
R23HL-22309-01 Cardiovascular pharmacodynamics in
immature dogs
ROlHL-22568-01 pH effect In heart cells-influence of
cardiac drugs (tissue culture, rats)
PHi
ROIHL 22641-01 Vantllition. perfusion, and tyilamic
arterial rellexes (dogs)
ROIHL 22836 01 The ipontaneoutly hypertenilve hidniy
(rats)
ROIHL 23624 01 Elfecl ol drugs on ischemic cardiac cells
(dogs, guinea pigs, pigs)
PHENYLALKYLAMINES, CATECHOLAMINES,
METANEPHRINE
•• ROIHL 14148 07 0002 The regional circulations
Catecholamine metabolism in subtypes ol hypertension
(human, animals)
ROIHL 1575806 Catecholamine release in the heart
(dogs)
PHENYLALKYLAMINES, CATECHOLAMINES,
NOREPINEPHRINE
R01HL01015 27 Hypertension and lett ventricular
hypertrophy (dogs)
ROIHL 03181 21 0027 Hemodynamics as applied to
surgical problems Hemodynamic studies ol the Gl tract
(dogs)
ROIHL 03941 18 Uterine blood How and changes in
pregnancy (sheep)
ROIHL 05883 18 0001 Rellex control ol resistance and
capacitance vessels Naturally occurring vasoactive
substances and the vascular neuroellectors (dog)
ROlHL-05883-18 0002 Rellex control ol resistance and
capacitance vessels - Adenosine, adenine nucleotides and
vascular smooth muscle (dog)
ROIHL 0588318 0003 Rellex control ol resistance and
capacitance vessels - Cardiac glycosides and sympathetic
nerve terminals in vascular smooth muscle
ROlHL-07835-17 Experimental hypertension and renal
circulation (rats, rabbits)
R01HL-08359-14 Morphopharmacology ol vascular
adrenergic transmission (rabbits, rats)
ROlHL-08659-14 Myocardial performance and metabolism
in the newborn (sheep)
POlHL-08682 15 0005 Regulation ol the cardiovascular
system - Smooth muscle and mechanical properties ol
blood vessels (dogs, human)
POlHL-08682-15 0011 Regulation ol the cardiovascular
system - Histochemistry and ultrastructure ol heart
innervation (dogs, ground squirrels)
POlHL-08682-15 0033 Regulation ol the cardiovascular
system - Functional and anatomical relations during
cardiac re-innervation (dog)
POlHL-10342-13 0019 The integrated lunction of
respiration and circulation - Cerebral circulation and
metabolism (dogs)
POlHL-10342-13 0024 The integrated function of
respiration and circulation - Cytochrome P450 and
physiological response to hypoxia (rats)
ROlHL-10942-09 Study ol genetic hypertension in rats
POlHL-11414-11 0028 Thrombosis and atherosclerosis
program - Catecholamine metabolism in the lung (rat)
POlHL-11678-11 0051 Cardiovascular dynamics and their
control - Transient glomerular nitration dynamics (dogs)
ROlHL-12614-09 Microcirculatory control mechanisms and
hypertension (bats, rats)
** ROlHL-12647-08 Inactivation of norepinephrine in vascular
tissue
** ROIHL- 12648-09 Catecholamine metabolism in
hypertensive diseases (human)
ROlHL-12740-10 Hypocholesterolemic agents-
Stereochemistry (rats)
ROlHL-12775-08 Cerebral microcirculation (mice)
ROlHL-12827-08 Regulation ol sodium excretion (dogs,
rats)
POlHL-13108-09 0017 Clinical heart transplantation -
Electrophysiology ol the transplanted denervated human
heart
** ROlHL-13315-08 Disposition ol vasoactive hormones In
mammalian lung (rats, rabbits, human)
ROlHL-13595-08 Renin and vascular hyper-reactivity in
hypertension (human, rats)
** ROlHL-14148-07 0002 The regional circulations -
Catecholamine metabolism in subtypes ol hypertension
(human, animals)
P50HL-14159-08 0008 Specialized center ol research in
hypertension - Renal junction and sodium metabolism in
hypertension (rats, human, rabbits)
P50HL-14159-08 0018 Specialized center ol research in
hypertension - Sympathetic nervous system in hypertension
(rats)
P50HL-14159-08 0020 Specialized center ol research in
hypertension - Renin-mineralocorticoid system in
hypertension (human, rat, dog)
POlHL-14388-07 0151 Regulation of the circulation in
pathological states - Catecholamine release in potassium
ion-free contractures in the caudal artery
P01HL14388-07 0158 Regulation of the circulation in
pathological states - Developmental aspect of abnormal
vascular reactivity (rats)
POlHL-14388-07 0163 Regulation of the circulation in
pathological states - Adrenergic receptors in coronary
vessels (dogs)
POlHL-14388-07 0168
pathological states -
tissue culture)
Regulation of the circulation in
Ionic basis of depolarization (rats.
•EiKhidat niutin* milhodotogy OR coven only general projeeti which prKluda Indexing at the ipMlfIc laval.
"Oriented ilgnlflcantly to above lublact.
M Grant hai lubprojectt describing specific researeh aspects.
See Appendix for Investigator's name and grant number.
?msmmmm
PHE
408
POlHL-1438807 0179 Regulation of the circulation in
pathological states ■ Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
POlHL-14388-07 0186 Regulation of the circulation in
pathological states - Angiotension in modulation of
neurogenic vasoconstriction
P01HL-U388-07 0193 Regulation of the circulation in
pathological states - Ontogenesis of central nervous system
amines in hypertension (rats)
POlHL-1438807 0194 Regulation of the circulation in
pathological states - Dopamine-beta-hydroxylase localization
and release in hypertension
POlHL-1438807 0198 Regulation of the circulation in
pathological states - Humoral factors in vascular reactivity
in spontaneously hypertensive rats
POlHL-14388-07 0199 Regulation of the circulation in
pathological states - Adrenergic stimulation in
spontaneously hypertensive rats
POlHL-14388-07 0210 Regulation of the circulation in
pathological states - Effects of dietary sodium on blood
pressure and vascular reactivity
P01HL14388-07 0211 Regulation of the circulation in
pathological states - Choline acetyltransferase activity
(rats)
P01HL14388-07 0213 Regulation of the circulation in
pathological states - Regulation of the heart and peripheral
circulation in heart failure
POlHL-14388-07 0220 Regulation of the circulation in
pathological states - Pharmacology of the coronary
circulation in man
POlHL-14388-07 0229
pathological states
(human)
ROlHL-14545-06 Mechanics of compensatory ventricular
hypertrophy (dogs)
ROlHL-14713-06 Hypothermia and the heart (bats, guinea
pigs)
R01HL-14832-06 Myocardial cells -Autonomic and rhythmic
mechanisms (chick embryo, rats)
ROlHL-14944-07 Renal vascular reactivity in hypertensive
patient
R01HL-15S22-06 Influence of mannitol on ischemia
cardiac muscle (dogs, cats, rats)
ROlHL-1 6758-06 Catecholamine release in the heart
(dogs)
ROlHL-16037-06 Molecular properties of cardiac
adrenergic receptors
R01HL-16066-05 Studies on neurogenic control of the
circulation (human, dogs)
POlHL-16117-05 0006 Ion movements and membranes in
cardiovascular control - Neuroreceptors and cellular
excitation (fish)
POlHL-161 17-05 0008
cardiovascular control
Regulation of the circulation In
Mechanism of postural hypotension
Ion movements and membranes in
Arterial smooth muscle calcium
fluxes and contractility (rabbits)
ROlHL-16254-05 Pathogenesis of bubble and clot
formation (fish)
R01HL-16760-05 Dynamic control of coronary blood flow
(dogs)
POlHL-17382-05 0002 Chemical mediators of acute
pulmonary disorders - Chemical mediators and respiratory
mechanics in guinea pigs
ROlHL-1 7487-04 Adrenergic-vasoregulation interactions in
hypertension (human)
P50HL-1 7646-04 0014 Study of ischemic heart disease -
Progression of ischemic injury in conscious dogs (also
rabbits)
P50HL-1 7648-04 0028 Study of ischemic heart disease -
Electrophysiology of sympathetic innervation in tissue
culture
ROlHL-17724-03 Oral contraceptives and hypertension
(rats)
ROIHL-1 7853-03 Peripheral circulation in heart failure
(animals)
ROlHL-18080-03 Extrinsic control of intestinal
microcirculation (dogs)
ROlHL-18148-04 Adrenal catecholamine secretion
R01HL-I8199-03 Effects of ions on vascular reactivity
ROlHL-18272-03 Heart adenyl cyclase complex (beef
heart)
P50HL-183 18-03 0011 Pathogenesis and complications of
hypertension - Adrenergic function-Renin and
mineralocorticoid activity (human)
P50HL-18318-03 0019 Pathogenesis and complications of
hypertension - Renin-angiotensin system in blood pressure
regulation (human, rat, dog)
P50HL-18323-04 0041 SCOR hypertension center -
Measurement of sympathetic response in hypertensive
patients
ROlHL-18371-03 Pulmonary hypertension and ventilation
pathophysiology (dogs)
POlHL-18575-03 0005 Mechanisms of vascular changes
in hypertension ■ Renin synthesis in normotensive and
hypertensive pigs (also rats, dogs)
ROlHL-18599-02 Cardiovascular pharmacology of
ionophores (dogs)
ROlHL-18601-01 Regulation of neurotransmitter release by
adenosine (rats)
ROIHL- 189 52-03 Metabolism in perfused fetal and
newborn rabbit lungs
Experimental neurogenic
Biochemistry and regulation of
Hypoxiainduced relaxation of vascular
Prostaglandins and hypertension (human.
POlHL-18974-03 0010
hypertension program
PNMT in brain (rats)
ROlHL-18995-04 Cardiovascular determinants of
catecholamine release (dogs)
ROlHL-19039-03 Circulation studies by one vs two circuit
model (dogs)
ROlHL-19082-01
smooth muscle
ROlHL-19229-02
rats, dogs, rabbits)
POlHL-19242-02 0007 Study of vascular smooth muscle -
NE release in and reactivity of vascular smooth muscle
(animals)
POIHL 19242-02 0008 Study of vascular smooth muscle
NE release in and reactivity of vascular smooth muscle
(rats)
ROlHL-19251-03 An index of sympathetic activity in
hypertension (rats)
ROlHL-19287-03 The antihypertensive function of the
renal medulla (human, rats, rabbits)
POlHL-19737-02 0002 Cellular and molecular aspects of
respiratory physiology - Airway smooth muscle in health
and disease (human, animals)
ROlHL-19974-02 Psychologic-behavioral influences on
heart pathology (rats)
ROlHL-19997-02 Prostaglandin precursors and intestinal
vasculature (cats, rabbits)
ROlHL-20339-02 Vascular alpha-adrenergic receptor
molecular properties
R01HL-20399-03 Vascular control in experimental diabetes
mellitus (dog)
ROlHL-20401-03 Relationship of insulin to catechol
cardiomyopathy (rabbit, pig)
ROlHL-20429-03 Study of effects of diabetes reactivity
(miniature pigs, rats)
ROlHL-20439-02 Effects of insulin on neurovascular
transmission (human, rats, rabbits, hamsters)
ROlHL-20446-02 Autonomic neuropathy in diabetic mice
(also rats)
POlHL-20581-01 0001 Vascular neuroeffector
mechanisms in health and disease - Vascular neuroeffector
mechanism (rabbits)
POlHL-20581-01 0004 Vascular neuroeffector
mechanisms in health and disease - Neuroeffector
characteristics of mesenteric and pulmonary blood vessels
(rabbits)
ROlHL-20685-02 Pituitary-adrenergic-ovarian vasomotor
interaction (dogs)
ROlHL-20783-02 Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
POlHL-21016-02 0013 Sickle cell anemia and other
hemoglobinopathies - Microcirculatory response to sickle
cell treated with anti-sickling agents (rats)
ROlHL-21099-02 Subcellular changes of blood vessels in
hypertension (rats)
ROlHL-21 187-01 Potassium, norepinephrine, and coronary
arterial tone (dogs)
ROlHL-213 18-02 Mechanisms of emotions' asthma
triggering effect (human)
ROlHL-21329-02 Beta-receptor regulation and cardiac
sites of drug action (cat, guinea pig, rat)
ROlHL-21367-02 Polyether ionophores -Synthesis of X537A
and analogs
POlHL-21584-02 0005 Respiratory mechanics in normal
and abnormal states - Regulation and behavior of airway
smooth muscle (human, animals)
ROlHL-21817-01 Catecholamines, blood pressure and
circulation
ROlHL-21860-18 Factors influencing responses to
adrenergic drugs (guinea pigs, rats, cats)
R23HL-21901-01 Hypertension, microvascular control and
exercise (rats)
R23HL-220 11-01 Adrenergic receptor cyclase system in
sensitized lung (rats, guinea pigs)
ROlHL-22077-01 Vasoactive amine disposition in cultured
endothelium (rabbits)
ROlHL-22170-01 Factors influencing transmission at
adrenergic synpases
ROlHL-222 16-02 Vascular mechanisms in renal
hypertension (dogs)
ROlHL-22226-01 Autonomic nervous elements in the
developing heart (rabbits)
ROlHL-22306-01 Renal catecholamines- Pathophysiology
of hypertension (dogs)
R23HL-22309-01 Cardiovascular pharmacodynamics in
immature dogs
ROlHL-22354-01 Alpha-adrenergic effects on heart
metabolism (rats)
ROlHL-22484-01
excitation (dogs)
R23HL-22490-01
heart cells
ROlHL-22514-01
catecholamines
ROlHL-22522-01
antagonists
ROlHL-22561-01
circulation (cats)
R01HL-22569-02
forces (dogs, cats)
Neural control of cardiac conduction and
Neurotransmitter receptors of cultured
Behavior patterns, stress, and
Cardioselectivity of beta-adrenoceptor
Hormonal control of mesenteric
Intestinal secretion -Capillary and tissue
PHE
POlHL-22619-01 0008 Cellular mechanisms of heart
failure - Molecular mechanisms and differential contractile
responsiveness in VSM (dogs)
ROlHL-22868-01 Presynaptic regulatory mechanisms in
hypertension (rats, dogs)
ROlHL-23209-01 Autonomic receptors of the pulmonary
vasculature (mammals)
ROlHL-23600-01 Ions, water, and hypertension (human,
dogs, rats)
PHENYLALKYLAAAINES, CATECHOLAMINES,
NORMETANEPHRINE
ROlHL-20194-01 Brain catecholamines in control of blood
pressure (rats)
PHENYLALKYLAMINES, CATECHOLAMINES
INHIBITORS
R01HL17370-03 Synaptic chemistry and cardioregulation
in Limulus
** ROlHL-20439-02 Effects of insulin on neurovascular
transmission (human, rats, rabbits, hamsters)
ROlHL-22170-01 Factors influencing transmission at
adrenergic synpases
ROlHL-22573-01 Treatment of post surgical
vasoconstriction (dogs, monkeys, human, rats)
** ROlHL-22873-01 Adrenoceptor interconversion and
hormone homeostasis
ROlHL-23209-01 Autonomic receptors of the pulmonary
vasculature (mammals)
PHENYLALKYLAMINES, METHOXAMINE
POlHL-10436-13 0014 A multidisciplinary study of
congenital heart disease - Cardiovascular pharmacology
(dog)
ROlHL-14899-07 Mechanism and prevention of cardiac
arrhythmias (dogs)
ROlHL-19451-03 0001 Functional characteristics of the
left heart - Ventricular performance using epicardial
radiopaque markers (human)
ROlHL-19451-03 0003 Functional characteristics of the
left heart - Left ventricular segmental contraction (human
dogs)
ROlHL-20783-02 Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
PHENYLALKYLAMINES, PHENETHYLAMINES
(GENERAL)
ROlHL-13315-08 Disposition of vasoactive hormones in
mammalian lung (rats, rabbits, human)
PHENYLALKYLAMINES, SALBUTAMOL
ROlHL-20783-02 Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
R23HL-21539-02 Mechanical properties of isolated small
bronchioles (rabbits)
PHENYLALKYLAMINES, TERBUTALINE
ROlHL-20783-02 Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
ROlHL-20989-01 Pathophysiology of bronchial asthma
(sheep, dogs)
ROlHL-21314-02 Respiratory tract secretion of ions, water
and mucus (human, dogs)
PHENYLALKYLAMINES, VERAPAMIL
P01HL-06308-18 0037 Mechanisms and therapy of
circulatory disease - Electrophysiology, blood flow, and ANS
in ventricular fibrillation (dogs)
POlHL-06308-18 0038 Mechanisms and therapy of
circulatory disease - Electrophysiology of ventricuair
arrhythmias associated with ischemia (dogs)
POlHL-06308-18 0039 Mechanisms and therapy of
circulatory disease - ANS in regulation of electrophysiology-
Role of cyclic nulceotides (animals)
ROlHL-08508-15 Cardiac conductivity and automaticity
(human, dogs, rabbits)
POlHL-11351-12 0001 Cellular and molecular
mechanisms of myocardial function - Ionic control of
myocardial contractility (animals)
POlHL-11351-12 0013 Cellular and molecular
mechanisms of myocardial function - Ion exchange in the
perfused septum high-resolution technique (rabbits, rats)
ROlHL-12415-10 Evaluation of left ventricular function
(dogs, rabbits)
POlHL-12738-10 0076 Physiologic pharmacology and its
clinical applications - Pediatric cardiac electrophysiology
and pharmacology (human, dogs)
POlHL-12738-10 0080 Physiologic pharmacology and its
clinical applications - Electrophysiology of cardiac muscle
in the mitral valve (monkeys)
POlHL-12738-10 0081 Physiologic pharmacology and its
clinical applications - Ultrastructural and electrophysiologic
alteration of myocardium (human, dogs)
POlHL-12738-10 0109 Physiologic pharmacology and its
clinical applications - Effects of calcium blockers on
skeletal and cardiac muscle (cats)
POlHL-12738-10 0132 Physiologic pharmacology and its
clinical applications - Coronary occlusions and arrhythmias
(dogs)
POlHL-12738-10 0136 Physiologic pharmacology and its
clinical applications -
ROlHL-14614-07 Voltage control of contraction in heart
(sheep)
(contd)
'Excludes routine methodokiey OR covers only general projects which preclude indexing at the specific level.
••Oriented significantly to above subject
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
PHE
ROIHI 14899 07 Mtchanism and ptevention ol cardiac
aiitiythmias (dogs)
POIHL 1498!) 0/ 0012 Adaplation to hypoxia Direct
iMicI ol hypoxia on pulmonary vascular smooth muscle
(rats. do|s)
POIHL 1SI940' 0004 Pathophysioloiy ol
cardiopulmonary dyslunction Specialised electiophysiology
libers tiectrogenic basis ot glycosides (mammals)
Mechanisms ol cardiac autorhythmicity
Role ol calcium and thyronine in heart
Energy loss microanalysis ol myocardial
Eleclrophysiology alter healed myocardial
ROIHI 161350b
(dogs, bats)
ROIHI 16436 04
tunction (rats)
ROIHL'16454 03 Vascular muscle reactivity in
hypertension (human, rats)
ROIHL 18032 03 Development ol normal and myopathic
mammalian heart (hamsters)
ROIHL 19045 03 Eleclrophysiology ol cardiac automaticity
(human, dogs)
ROIHL 19394 03 Biochemistry and regulation ol taurine in
the heart (rats, guinea pigs, cats)
ROIHL 19653 03 Circulatory system ellects ol angiotensin
analogs (rats)
ROIHL 21371-02
cations
ROIHL 2173501
Inlarction (cats)
R01HL2174201 Frequency-dependent drug actions in
cardiac muscle (rabbits)
ROlHL-22354 01 Alpha adrenergic ellects on heart
metabolism (rats)
ROlHL-23599-01 Mechanisms ol ischemic rhythm
disorders (dogs)
PHENYLAAAIDES, ACETOPHENETIDIN
ROlHL-00340-29 Electrolyte disturbance in cardio-renal
disease (human, dogs, rats)
POlHL-08899-14 0026 Tolerance to respiratory gases in
health and disease Ellects ol oxygen on central nervous
system tunctions (rats, rabbits)
PHENYLAAAIDES, UDOCAINE
ROlHL-04666-19 Artilicially paced hearts-Technology.
physiology (human, dogs)
ROlHL-05806-18 Analysis ol antiarrhythmic agents (dogs.
rabbits)
ROlHL-08508-15 Cardiac conductivity and automaticity
(human, dogs, rabbits)
P01HL-U310-12 0078 Mechanisms ol cardiovascular
disease - Ventricular arrhythmias in acute myocardial
inlarction (dogs)
** POlHL-12738-10 0044 Physiologic pharmacology and its
clinical applications - Cardioactive drugs and
electrophysiological properties ol cardiac cells (sheep)
POlHL-12738-10 0081 Physiologic pharmacology and its
clinical applications - Ultrastructural and electrophysiologic
alteration of myocardium (human, dogs)
POlHL-12738-10 0108 Physiologic pharmacology and its
clinical applications - Developmental eleclrophysiology and
pharmacology (human, animals)
POlHL-12738-10 0110 Physiologic pharmacology and its
clinical applications - Physiology and pharmacology ol
arrhythmias (dogs)
POlHL-12738-10 0132
clinical applications
(dogs)
ROlHL-14832-06 Myocardial cells -Autonomic and rhythmic
mechanisms (chick embrvo. rats)
ROlHL-14899-07 Mechanism and prevention ol cardiac
arrhythmias (dogs)
ROIHL-16076-06 Eleclrophysiology ol librillation and
defibrillation (human)
P50HL-1 7648-04 0014 Study of ischemic heart disease -
Antidysrhythmic drugs and mammalian cardiac Purkinje
libers (sheep, dog)
ROlHL-20283-02 Maintenance of cellular integrity in
ischemic hearts (cats)
R23HL-21151-02 Ischemic myocardium -Delivery of blood
flow and drugs (dogs)
ROlHL-21158-02
afferents (cats)
ROlHL-21672-01
cardiac cells
ROlHL-21742-01 Frequency-dependent drug actions in
cardiac muscle (rabbits)
ROlHL-22568-01 pH eflect in heart cells-Influence of
cardiac drugs (tissue culture, rats)
ROlHL-23599-01 Mechanisms of ischemic rhythm
disorders (dogs)
ROlHL-23624-01 Eflect of drugs on ischemic cardiac cells
(dogs, guinea pigs, pigs)
PHENYLAMIDES, PRACTOLOL
P01HL-12373-10 0013 Cardiopulmonary physiology and
pathophysiology - Effects ol cardiovascular drugs on lett
ventricular lunction (dogs)
P01HL-14388-07 0163 Regulation ol the circulation in
pathological states - Adrenergic receptors in coronary
vessels (dogs)
ROlHL-15002-07 Biochemical pharmacology ol guanylate
cyclase in lung (cattle, rats)
ROlHL-18050-04 Mechanisms of cardiovascular
teratogenesis (chick embryo) k embryo)
Physiologic pharmacology and its
- Coronary occlusions and arrhythmias
Cardiac receptors w»ith vagal C-liber
Antiarrhythmic drug action on VMAZ ol
ROIHI 19782 0?
heart (dogs)
ROIHL 20190 0?
(dogs)
ROIHL 2252? 01
antagonists
ROIHL 23599 01
disorders (dogs)
409
Pharmacologic studies on the ischemic
Pathogenesis ol cardiac hypertrophy
Cardioseleclivity ol beta adrenoceptor
Mechanisms ol ischemic rhythm
PHENYLAMIDES, PROCAINE AMIDE
SEE ALSO PAMIN0BEN20ATE. PROCAINE HYDROCHLORIDE
R01HL07776 15 Sudden death and cardiac arrhythmias
(human, dogs, cats)
POIHL 11310 12 0078 Mechanisms ol cardiovascular
disease Ventricular arrhythmias in acute myocardial
inlarction (dogs)
Physiologic pharmacology and its
Clinical pharmacology ol cardioactive
POIHL 12738 10 0001
clinical applications
drugs (human)
POIHL 12738 10 0035
clinical applications
Physiologic pharmacology and its
Function and dyslunction ol the
sinoatrial node (human)
** POIHL 1273810 0044 Physiologic pharmacology and its
clinical applications Cardioactive drugs and
electrophysiological properties ol cardiac cells (sheep)
POlHL-12738-10 0076 Physiologic pharmacology and its
clinical applications Pediatric cardiac eleclrophysiology
and pharmacology (human, dogs)
ROlHL-14899-07 Mechanism and prevention ol cardiac
arrhythmias (dogs)
R01HL16076-06 Eleclrophysiology ol librillation and
delibrillation (human)
P50HL-17648-04 0014 Study ol ischemic heart disease
Antidysrhythmic drugs and mammalian cardiac Purkinje
libers (sheep, dog)
P50HL-1 76 70-04 0011 Study ol ischemic heart disease
Pharmacology of ischemic myocardium (dogs)
ROlHL-21672-01 Antiarrhythmic drug action on VMAZ ol
cardiac cells
ROlHL-21742 01 Frequency-dependent drug actions in
cardiac muscle (rabbits)
ROlHL-23624-01 Effect ol drugs on ischemic cardiac cells
(dogs, guinea pigs, pigs)
PHENYLAMINES, NEOSTIGMINE
** P01HL07896-15 0056 Environmental biomedical research
program - Neuromuscular blocking effects of
nondepolarizing muscular relaxants (frogs)
ROlHL-22546-02 Baroreceptor reflex mechanisms in man
PHENYLBUTAZONE
SEE PYRAZOLONES. PHENYLBUTAZONE
PHENYLCARBOXYLATES, BENZOATES
SEE ALSO SULFONAMIDES. PROBENECID
ROlHL-200 16-03 Chelator development for thalassemia
(human, mice. rats. dogs, monkeys)
ROlHL-20909-02 Clolibrate-enhanced lipid oxidation by
peroxisomes (rats)
PHENYLCARBOXYLATES, SALICYLATES
ROlHL-00340-29 Electrolyte disturbance in cardio-renal
disease (human, dogs, rats)
POlHL-08805-15 0047 Regulation of ventilation and
pulmonary circulation - Extracranial metabolic control of
ventilation (dogs, goats)
POlHL-14388-07 0231 Regulation of the circulation in
pathological states - Mechansim ol cutaneous
vasodilatation in Paget's disease ol bone
ROlHL-14717-06 Hemodynamics and heart structure-
Ventricular overload (dogs)
ROlHL-16246-06 Immunologic studies in
postpericardiotomy syndrome (human)
ROlHL-20558-02 Cardiac electrophysiology-Ellects of ions
and drugs
PHENYLCARBOXYLATES, SALICYLATES, ACETYL-
POlHL-06350-17 0019 Hemostasis research program
project - Microcirculation (human, rats, rabbits)
POlHL-07293-17 0058 Non-invasive cardiovascular
measurements - Peripheral duplex scanner physiologic
evaluation
** POlHL-07896-15 0057 Environmental biomedical research
program - Effects of dipyridamole and aspirin on
decompression thrombocytopenia (human)
ROlHL-08888-12 Cooperative study of drugs and coronary
heart disease (men)
ROlHL-08892-10 Cooperative study of drugs and coronary
heart disease
POlHL-08899-14 0026 Tolerance to respiratory gases in
health and disease - Effects of oxygen on central nervous
system functions (rats, rabbits)
ROlHL-10445-09 Cooperative study of drugs and coronary
heart disease (men)
ROlHL-10622-12 Volumes and compliance of pulmonary
circulation (human, dogs)
ROlHL-10705-09 Cooperative study ol drugs and coronary
heart disease (men)
ROIHL 11372-08 Cooperative study ol drugs and coronary
heart disease (men)
POlHL-1 14 14-11 0004 Thrombosis and atherosclerosis
program - Platelet function and nonthrombogenic surfaces
(human)
PHE
ROIHI 13036 08 Coronary thrombosis Fllei-lt on
myocardium and in vivo detection (dogs, monkeys)
ROIHI 13595 08 Renin and vascular hyper reactivlly in
hypertension (human, rats)
POIHL 13738 08 0003 Cardiac assist devices and
artilicial hearts Pathophysiological ellects ol the artificial
heart (calves)
ROIHL 13/54 08 Postoperative Ihromboembolism in
surgical patients (human)
P50HL 14147 08 0001 Speciali«d center ol research in
thrombosis Role ol aspirin, other anti platelet agents in
platelet lunction (rat. human)
P50HL 1415307 0012 lohns Hopkins Lung Center
Chronic diseases ol airways Aspirin intolerance in
reversible lung disease (human)
P50HL 14217 08 0058 Specialized center ol research in
thrombosis Mechanisms ol induction and inhibition ol
platelet reaction (human, pig)
ROIHL 14571 05 Myocardial preservation and coronary
reperiusion (baboons, dogs)
ROlHL-14844 06 Mucous glycoprotein in human respiratory
epithelium (also wheat)
ROIHL 14890 07 Platelet prostaglandins (human, rabbits)
ROIHL 15374 03 Cooperative study ol drugs and coronary
heart disease (human)
ROIHL 15681 06 Coronary (low studies ol partially
obstructed vessels (dogs)
POlHL-16387-04 0005 The blood vessel and
thrombogenesis Fluid engineering considerations in
thrombogenesis
ROlHL-16437-05 Drug treatment ol atherosclerosis
(rabbits, monkeys)
ROlHL-1648904 Renal prostaglandins-Synthesis and
lunction (human, dogs, rats)
ROIHL 16496-04 Prostaglandins and renin experimental
hypertension (rabbits)
ROlHL-16634-13 Regulation ol metabolism in libroblasts
and platelets (human, rabbits, sheep)
POlHL-17382-05 0001 Chemical mediators ol acute
pulmonary disorders - Chemical mediators and respiratory
mechanics in humans
POlHL-18576-03 0001 Thrombosis research program
project - Platelet damage Irom physical lorces and
artilicial surfaces (human)
ROlHL-18718-04 Prostaglandin precursors and vascular
reactivity (dogs)
* ROlHL-18738-02 Prevention ol postoperative venous
thrombi (human, cattle)
POlHL-18827-02 0006 Platelet vessel wall interactions in
thrombogenesis - Platelet immune injury in man
ROlHL-18932-03 Brain microcirculation observed m vivo
affer trauma (mice)
ROlHL-19001-03 Atherosclerosis in bleeder and drug
treated subjects (pigs)
ROlHL-19112-03 Atherosclerosis studies (monkeys)
ROlHL-19202-03 Adenosine, prostaglandins in relation to
coronary How (guinea pigs)
ROlHL-19451-03 0004 Functional characteristics ol the
Icff heart - Quantitative coronary arteriography (human)
POlHL-19717-02 0007 Response of the lung to injury -
Cellular level studies ol prostaglandin-like molecules
(cattle)
Thromboembolic diseases (human)
Atherosclerosis and arterial cell tunctions
Coronary vasomotion (dogs, pigs)
Platelet inhibitor drug in coronary surgery
ROlHL-20337-02
ROlHL-20924-02
(human, rabbits)
R23HL-21298-02
ROlHL-21533-02
(human)
POlHL-22163-01 0003 Surface thrombogenesis -
Mechanisms and prevention - In vivo mechanisms ol
biomaterial thrombogenesis and its prevention (baboons)
R23HL-22309-01 Cardiovascular pharmacodynamics in
immature dogs
ROlHL-22445-01 Platelet inhibitors-Effect on coronary
bypass gratis (dogs)
ROlHL-22527-01 Prostacyclin-thromboxanes in the
cardiovascular system (human, rabbits)
ROlHL-22573-01 Treatment ol post surgical
vasoconstriction (dogs, monkeys, human, rats)
POlHL-22602-01 0001 Pathophysiology ol the
endothelium - Platelet-endothelial interactions in vitro
(human, cattle)
ROlHL-22783-01 Hemodynamic induction ol intiraal
libromuscular lesion
ROlHL-22951-01 Studies on the affect ol vitamin E on
platelets (human, rats)
** NOlHV-52901-06 Aspirin-myocardial inlarction study
** NOlHV-52941-04 Center for aspirin-myocardial infarction
study (human)
PHENYLCARBOXYLATES, SALICYLATES, P-
AMINO-
P50HL-14237-07 0006 Support lor arteriosclerosis center
- Drug treatment ol lamilial hyperbetalipoproteinemia
(human)
POlHL-20993-02 0004 Population dynamics ol arterial
cells in atherogenesis - Modilications ol cholesterol balance
related to arterial cell divisions (swine)
PHENYLEPHRINE
SEE PHENOLIC AMINES. NEOSYNEPHRINE
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level
"Onented signilicantly to atiove subject.
M Grant has subprojects describing specihc research aspects.
See Appendix for investigator's name and grant number.
mm^?^
Control of glycogen synthesis in heart
Hormonal control of lipid and lipoprotein
PHE
PHENYLETHANOL
SEE PHENYLALKANOLS, PHENYLETHANOL
PHENYLETHYLAMINES
SEE PHENYULKYLAMINES. PHENETHYLAMINES (GENERAL)
PHENYLETHYLBIGUANIDE
SEE GUANIDINES, BIGUANIDES, PHENETHYLBIGUANIDE
PHENYLHYDRAZINES
SEE AZO COMPOUNDS. HYDRAZINES. PHENYLHYDRAZINES
PHEOCHROMOCYTOMA
SEE NEOPLASMS OF NERVOUS SYSTEM. PARAGANGLIA
NEOPUSMS. PHEOCHROMOCYTOMA
PHLEBOGRAPHY (VENOGRAPHY) - GENERAL
SEE CARDIOVASCUUR VISUALIZATION. VENOGRAPHY
(GENERAL)*
PHLEBOTOMY - BLOODLETTING
SEE BLOODLETTING
PHLORETIN
SEE PHENONES. PHLORETIN
PHONOANGIOGRAPHY
SEE CARDIOVASCULAR DISORDERS DIAGNOSIS, SOUND
MEASUREMENTS, VASCULAR*
PHORBOL
SEE LIPIDS. OILS. CROTON OIL
PHOSPHATASE INHIBITORS
SEE ENZYME INHIBITORS, PHOSPHATASE INHIBITORS
PHOSPHATASES
SEE ALSO NUCLEOTIDASES
SEE ALSO PHOSPHODIESTERASES
ROlHL-13630-08
(cattle)
R01HL15930-06
synthesis (rats)
ROlHL-1863103 Ultrastructural correlates of myocardial
ischemia (rats, swine)
ROlHL-23587 01 Phosphorylation of myocardial protein
(guinea pigs)
ROlHL-23615-01 Biochemistry of contractile proteins
(chicken, rabbit)
PHOSPHATASES, ADENOSINE TRIPHOSPHATASE
SEE ALSO BLOOD COAGULATION. THROMBOSTHENIN
SEE ALSO MUSCLE PROTEINS (AND CONTRACTILE PROTEINS),
MYOSIN
ROlHL-01974-24 Ion-pump in the erythrocyte (rabbits,
guinea pigs)
ROlHL-02493-22 Kidney function in experimental heart
failure (dogs, rats)
ROlHL-03290-22 Controls of cardiac and vascular smooth
muscles (cats, rats, dogs)
ROlHL-0594918 Biochemistry of muscle contraction (rats,
rabbits)
P01HL06285-18 0173 Cardiovascular-respiratory
physiology and biochemistry - Skeletal and cardiac muscle
function
POlHL-0628518 0195 Cardiovascular-respiratory
physiology and biochemistry - Thyroid thermogenesis and
sodium transport (rats)
P01HL06285-18 0196 Cardiovascular-respiratory
physiology and biochemistry - Hormonal regulation of
sodium transport-Epithelial cell membranes (toads)
POlHL-0631417 0055 Immunologic mechanisms in
cardiovascular disease - Genetics and cell biology
POlHL-0666417 0036 Cardiopulmonary function in
remediable vascular disease - In vitro studies on the
mechanism of ischemic damage to cells (rabbits)
ROlHL-06924-16 Humoral and metabolic aspects of
cardiac function (mammals, non-human, human)
POlHL-07896-15 0032 Environmental biomedical research
program - Fluorometry study of brain exposed to hyperbaric
oxygen (dogs, cats)
POlHL-07896-15 0049 Environmental biomedical research
program - Effects of hyperbaric oxygen and pressure on
cerebral enzymes (rats)
ROlHL-0889314 Structure and function of membrane
proteins (human)
ROlHL-09234-13 Amino acids of contractile proteins of
failing hearts (dogs, hamsters)
ROlHL-09544-12 Biochemistry of contractile proteins
(animals)
ROlHL-09906-13 0018 Membrane transport processes in
red blood cells - Rapid photolytic release of ATP from a
protected analog-Na-K pump of RBC ghosts
ROlHL-10608-12 Digoxin-specific antibodies (human)
P01HL-1135M2 0004 Cellular and molecular
mechanisms of myocardial function - Molecular
mechanisms of contractile function and differentiation
(animals)
POlHL-1135112 0006 Cellular and molecular
mechanisms of myocardial function - Molecular physiology
and energetics of muscle (frogs)
POlHL-11351-12 0019 Cellular and molecular
mechanisms of myocardial function - Mechano-chemical
kinetics of small perturbations
410
■ POlHL-1 1351-12 0024 Cellular and molecular
mechanisms of myocardial function - Steady state and
transient kinetics of frog myosin, S-1. and ATPase
ROlHL-12990-09 Control of antidiuretic hormone secretion
and metabolism (dogs, rats, rabbits)
ROlHL-13237-09 Erythrocytes during early development
(human, animals)
ROIHL 1325608 Amino acid transport by red cell
membranes (pigeons)
R0IHL-13e36-08 Effects of pharmacologic agents on heart
metabolism (human, rodents)
POlHL-1373707 0031 Assisted circulation - Myocardial
ischemia -Biochemical changes (dogs)
ROlHL-13870-09 Control of myocardial sarcotubular
calcium stores (dogs)
ROlHL-14020-06 Characterization of myosin from blood
platelets (rabbit)
POlHL-14388-07 0172 Regulation of the circulation in
pathological states - cAMP-dependent protein kinase from
heart and vascular smooth muscle (guinea pigs)
' POlHL-14388-07 0173 Regulation of the circulation in
pathological states - Mechanisms of cardiac myosin ATPase
POlHL-14388-07 0175 Regulation of the circulation in
pathological states - Functional studies of selected proteins
from cardiac muscle
P01HL-144I407 0014 Environmental influences on
cardiorespiratory and cellular functions - Temperature and
acid-base status in tissues, cells, and subcellular system
POlHL-14414-07 0016 Environmental influences on
cardiorespiratory and cellular functions - Effects of
pressure on membrane and cellular function (human,
rabbits)
ROlHL-14483-08 Energy conservation in heart
mitochondria (cattle, E coli, human)
ROlHL-14820-07 Factors affecting physiology of biological
membranes (human)
P50HL-1506107 0005 Response of lung to injury - Airway
smooth muscle in health and disease (dogs, guinea pigs)
ROlHL-15391-07 EPR studies on rotational motion of
myosin and actin
ROlHL-15498-06 Effects of physical training on heart
(rats)
ROlHL'15522-06 Influence of mannltol on ischemia
cardiac muscle (dogs, cats, rats)
ROlHL-15692-07 Force and speed in skeletal and cardiac
muscle
R01HL1579306 Molecular aspects of erythrocyte
membrane resealing (human)
R01HL15799-04 Effect of anesthetics on myocardial
function (cats)
R01HL16052-05 Cardiac glycosides -Mechanism of
inotropic action (dogs)
POlHL-161 17-05 0002 Ion movements and membranes In
cardiovascular control - Fluorescence and excitation-
contraction coupling in heart (frogs)
POlHL-161 17-05 0008 Ion movements and membranes in
cardiovascular control - Arterial smooth muscle calcium
fluxes and contractility (rabbits)
ROlHL-163 18-21 Biochemistry and pharmacology of Na-K
transport
R01HL16549-04 Cardiotonic steroid-NaK ATPase
interactions (cattle)
POlHL-16607-05 0001 Calcium ion and control of
cardiovascular function - Bilayer lipid membranes.
antibiotic probes, and SR function
POlHL-16607-05 0003 Calcium ion and control of
cardiovascular function - Calcium transport in
sarcoplasmic membranes (animals)
POlHL-16607-05 0005 Calcium ion and control of
cardiovascular function - Chemical modifications of the
sarcoplasmic reticulum membranes (rabbits)
POlHL-16607-05 0007 Calcium ion and control of
cardiovascular function - Ultrastructure and conformation
in sarcoplasmic reticulum (rabbits)
ROlHL-166 11-04 Digitalis-receptor of the heart (guinea
pigs, rats)
R01HL16637-04 Development and regression of cardiac
hypertrophy (rats)
POlHL-16683-04 0001 Function and growth of cardiac
and skeletal muscle - Light chains of the skeletal and
cardiac myosin molecule (rabbits, frogs)
POlHL-16683-04 0002 Function and growth of cardiac
and skeletal muscle - Myosin, actin, ATP, interaction in
solution
POIHL- 166 83-04 0006 Function and growth of cardiac
and skeletal muscle - Chemical studies of the contractile
system -Development of new reagents
ROlHL-16706-04 Excitation-contraction coupling and heart
failure (dogs, rabbits)
POlHL-1676905 0002 Pathobiologic and host defense
reactions in the lung - Pathogenesis of complement
dependent injury to the lungs (rabbits)
P60HL-17269-04 0003 National heart and blood vessel
research and demonstration center - Atherosclerosis -Fatty
acid metabolism in cardiovascular tissue (human, chicken)
P60HL-1 7269-04 0017 National heart and blood vessel
research and demonstration center - Cell membrane (dogs.
rabbits)
P60HL-17269-04 0018 National heart and blood vessel
research and demonstration center - Mitochondria and
energetics (rabbits, dogs)
'Excludes routine methodotegy OR covers only leneral projects which preclude indexing
"Oriented si|nificantly to above subject.
PHO
P60HL-17269-04 0019 National heart and blood vessel
research and demonstration center - Sarcoplasmic
reticulum (dog, rabbit, hamster, cat)
P60HL-17269-04 0022 National heart and blood vessel
research and demonstration center - Medicinal chemistry
(rabbit, dog, guinea pig)
ROIHL- 17631 05 Experimental congestive heart failure and
hypertrophy (cats)
P50HL-17648-04 0023 Study of ischemic heart disease -
Chemical mediators of inflammation in acute myocardial
infarction (mammals)
P50HL- 17669-04 0006 Ischemic heart disease center
(SCOR) ■ Studies of hypoxic, acidotic and ischemic cardiac
muscle (dogs)
P50HL-1 7682-04 0024 Study of ischemic heart disease -
Phosphorylation of cardiac contractile proteins during
ischemia (rat. guinea pig)
ROlHL'17796-04 Importance of aminosugars in digitalis
activity (cats, rabbits)
ROlHL-1 7879-04 Molecular structure of the ouabain
sensitive ATPase (dogs)
ROlHL-18003-05 Digitalis-Mechanism and reversal studies
(dog, sheep, duck, guinea pig. human)
R01HL18053-03 Intracellular ionic activities in heart
muscle (frogs)
ROIHL 18176-02 Effect of thyroid hormone on cultured
cardiac cells (rats)
ROlHL-18179-03 Heart, platelet, and muscle myosins and
actomyosins (cattle)
ROIHL 18185-04 Cardiac glycosides and diuretics-Role of
NaO pump (dogs)
POIHL- 18208-04 0001 Center for the study of blood cell
rheology - Physiological basis of reversible erythrocyte
shape change (human, firefly)
P01HL18208-04 0005 Center for the study of blood cell
rheology - RBC deformability and capillary flow
interrelations (human, mice)
POlHL-18208-04 0007 Center for the study of blood cell
rheology RBC membrane protein (human)
ROlHL'18255-04 Lipid-protein interactions and calcium
transport (models)
ROlHL-18516-03 Atherosclerosis and the arterial
contractile proteins (pigs, rabbits)
ROlHL-18527-03 Subcellular response of heart to
functional overload (hamsters, rats)
ROlHL-18551-03 Spectrin, actin, lipid and red cell
membrane structure
POlHL-18575-03 0001 Mechanisms of vascular changes
in hypertension - Arteries and resistance vessels in
hypertension (pigs, rats)
ROlHL-18598-03 Role of Na. K-ATPase inhibition on
digitalis action
POlHL-1870803 0007 Oxygen, energy and contractility in
cardiac tissue - Surfaces, energy requirements, and
contractile proteins of cardiac cell in vitro
ROlHL-18798-04 0001 Nervous and ionic factors in
sudden cardiac death - Potassium loss during myocardial
ischemia (rabbits)
ROlHL-19068-03 Changes in membrane properties during
erythropoiesis (chick embryo)
ROlHL-19129-04 Cardiac glycosides-Mechanisms of
cellular actions
ROlHL-19 148-03 Myocardial organelle lipid structure and
function (dog, rat)
POlHL-19242-02 0006 Study of vascular smooth muscle -
The contractile system of vascular smooth muscle (swine,
rats)
ROlHL-19425-03 Cardiac function in hypertrophy (dog)
R01HL19461-03 Myocardial energetics in hypertrophy and
heart failure (rabbits)
R01HL19467-03 Regulation of blood pressure (rats, dogs)
R01HL19485-03 Calcium uptake by normal and failed
cardiac ATPase (dogs)
ROIHL 20262-02 Cardiac glycosides and the mechanism
of the sodium-potassium pump
ROlHL-20558-02 Cardiac electrophysiology-Effects of ions
and drugs
POlHL-20592-02 0001 Cell biology of cardiac and
skeletal muscle - Molecular mechanism of muscle
contraction (animals)
ROlHL-2071101 Structure-function relationships in red
cell NA-K pumps (goats)
ROlHL-20878-02 Cellular aspects of lung injury (rats.
rabbits)
POlHL-2098402 0001 Cellular mechanisms in cardiac
hypertrophy - Contractile proteins in cardiac hypertrophy
(rabbits, calves)
POlHL-2098402 0002 Cellular mechanisms in cardiac
hypertrophy - Thermodynamic, fluorescence, chemical
modification of hypertrophied heart myosin
POlHL-20984-02 0003 Cellular mechanisms in cardiac
hypertrophy ■ Fast-kinetics of myosin ATPase from normal
and hypertrophied heart (rabbits)
POlHL-20984-02 0004 Cellular mechanisms in cardiac
hypertrophy • Myofibril accumulation in cardiac and
vascular muscle cells in hypertrophy
P60HL-20985-01 0004 Northern California sickle cell
center - Characterization of irreversibly sickled cells
(human)
ROlHL'21014-01 Mechanism of the inotropic action of
cardiac glycosides
(oontd)
at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
iSSSS.^^
PHO
ROIHL 2103001 Cilcium regulation and hypertension
(rats)
R23HI 2119602 Digitalis induced arrhythmia and NAO KG
atpase activity (dogs)
R23m. 2141302 Structure and lunctlon of platelet
calcium binding protein (human)
ROIHL 21457 01 Cd/) side group geometry and
cardenolide activity (cats, guinea pigs)
ROIHL 2149302 Contractility in cardiac failure (hamsters)
ROIHL 2152502 Effect of cations, anions and water upon
blood vessels (dogs, rats)
ROIHL 21812 02 Actions of drugs and ions on cardiac
membranes (rabbits, guinea pigs)
ROIHL 2182001 Regulatory role of myosin in cardiac
hypertrophy (dogs)
ROIHL 21850 01 Calcium transport in the hypertrophied
myocardium (rats, animals)
ROIHL 22039 02 Ion transport in cardiac muscle (dogs.
rodents, cattle)
ROIHL 22135-01 Control of calcium fluxes across cardiac
membranes (dogs, rabbits, guinea pigs)
* ROIHL 2217401 Assembly of membranes in heart and
yeast mitochondria
ROIHL 2226401 Regulation of contraction in vascular
smooth muscle (dogs)
ROIHL 22361 01 Regulation of cardiac adaptation to
exercise (rats)
t POIHL 22619 01 Cellular mechanisms of heart failure
■• POlHL-2261901 0001 Cellular mechanisms of heart
failure Cell membrane isolation and reconstitution (dogs,
lambs)
'* POlHL-2261901 0002 Cellular mechanisms of heart
failure - Structure of sodium, potassium-adenosine
triphosphatase (lambs, dogs)
" POlHL-22619-01 0003 Cellular mechanisms of heart
failure - Digitalis induced inotropy in myocardial ischemia
heart failure (animals)
** POlHL-22619-01 0004 Cellular mechanisms of heart
failure - Mechanism of action of Na. K-ATPase (sheep,
cattle)
** POlHL-2261901 0005 Cellular mechanisms of heart
failure - Molecular mechanism of regulation of cardiac
muscle contraction (cattle)
•* POlHL-22619-01 0006 Cellular mechanisms of heart
failure - Phosphorylation of contractile proteins in cardiac
muscle contraction (dogs, rabb
** POlHL-22619-01 0009 Cellular mechanisms of heart
failure - Sarcoplasmic reticulum in cardiac, skeletal and
smooth muscle (rabbits, dogs)
POlHL-22619-01 0010 Cellular mechanisms of heart
failure - Mitochondria in heart and smooth muscle (rabbits,
rats, dogs)
ROlHL-22813-01 Palmitylcarnitine inhibition of ion pumps
in ischemia (dogs)
ROlHL-22845-01 Response of cardiac myosin to
hypertrophic stress (rabbits)
ROlHL-23128-01 Cardiac contractility-Ischemia and
hypoxia (rabbits, rats)
ROlHL-23161-01 0002 Biology of myocardial ischemia -
Palmitylcarnitine inhibition of ion pumps in myocardial
ischemia (dog. sheep)
ROlHL-23200-01 Isolation of CA binding proteins from
erythrocytes (human)
ROlHL-23206-01 Repetitive exercise and cardiac
enlargement (dogs)
ROlHL-23249-01 Actin-myosin interaction in pulmonary
smooth muscle (cattle)
ROlHL-23312-01 Hemodynamics and vasoactivity in renal
hypertension (human, dogs)
ROlHL-23587-01 Phosphorylation of myocardial protein
(guinea pigs)
R01HL-236I5-01
(chicken, rabbit)
ROlHL-23990-01 Role of phosphoprotein in cardiac
inotropic responses
** R01HL-23994-01 Biochemical properties of human cardiac
myosin
PHOSPHATES
SEE ALSO CARBAMYL PHOSPHATE
SEE ALSO NUCLEOTIDES
ROlHL-05556-19 Proteins, lipoproteins-Structure and
reactivity (chicken, human, diving mammals)
ROlHL-11511-10 Structure of ferritin and its role in iron
metabolism (horse, rats, human)
POlHL-13262-07 0016 Arterial wall in atherosclerosis -
Lipids in elastin preparations from atherosclerotic plaques
(human, animals)
ROlHL-15983-04 Regional myocardial blood flow (dogs)
ROlHL-16658-05 Intrarenal regulation of sodium
reabsorption
ROlHL-17494-07 Mechanism of liqand binding to
hemoglobin (human)
ROlHL-18819-07 Chemical studies on sickle cell
hemoglobin (human)
R23HL-19601-01 Cardiac response to chronic metabolic
acidosis (rats)
POlHL-20552-02 0010 The development and regression of
cardiac hypertrophy - Energy metabolism in the
hypertrophied heart animals
ROlHL-21786-01 Long-term effects of myocardial
protection (dogs, rats)
Biochemistry of contractile proteins
411
ROIHL 22845 01 Response of cardiac myosin to
hypertrophic stress (rabbits)
ROIHL 23153 01 Mechanisms of altered CA20 transport in
ischemic heart (dog. labbil)
PHOSPHATES, AlKYl PHOSPHATES, ETIDRONATf
ROIHI 16437 OS Drug treatment of atherosclerosis
(rabbits, monkeys)
PHOSPHATES, FLUOROPHOSPHATES, DFP
POIHL 185 76 03 0005 Thrombosis research program
proiect Molecular basis ol von Willebrand's disease and
hemophilia (human, cattle)
PHOSPHATES, POLYPHOSPHATES
ROIHL 18607 03 Metabolic and drug studies on
experimental fat embolism (mice)
ROIHL 1901103 Smooth muscle cell membrane
glycoprotein biosynthesis (cattle)
PHOSPHATES, PYROPHOSPHATES
P50HL 17669 04 0009 Ischemic heart disease center
(SCOR) Infarct volume 99Tc stannous pyrophosphate
myocardial scintigrams (dogs, human)
P50HL 17669-04 0023 Ischemic heart disease center
(SCCR) Patients with acute myocardial infarction and
myocardial ischemia (human)
PHOSPHATIDES
SEE PHOSPHOLIPIDS
PHOSPHATIDIC ACIDS
SEE PHOSPHOLIPIDS, PHOSPHOGLYCERIDES, PHOSPHATIDIC
ACIDS
PHOSPHATIDYL AMINO ACIDS
SEE AMINO ACIDS
PHOSPHATIDYL CHOLINE
SEE PHOSPHOLIPIDS, PHOSPHOGLYCERIDES, LECITHINS
PHOSPHATIDYLCHOLINE
CHOLINEPHOSPHOHYDROLASE
SEE PHOSPHOLIPASE, PHOSPHATIDYLCHOLINE
CHOLINEPHOSPHOHYDROLASE
PHOSPHATIDYLCHOLINE-
CHOLESTEROL:TRANSESTERASE
SEE TRANSACYLASES, LECITHIN-CHOLESTEROL
TRANSESTERASES
PHOSPHATIDYLCHOLINE
PHOSPHATIDOHYDROLASE
SEE PHOSPHOLIPASE, PHOSPHATIDYLCHOLINE
PHOSPHATIDOHYDROLASE
PHOSPHATIDYL ETHANOLAMINE
SEE PHOSPHOLIPIDS, PHOSPHOGLYCERIDES, PHOSPHATIDYL
ETHANOLAMINE
PHOSPHATIDYL INOSITOL
SEE PHOSPHOLIPIDS, PHOSPHOGLYCERIDES,
PHOSPHOINOSITIDES
PHOSPHATIDYL POIYGLYCEROL
SEE PHOSPHOLIPIDS, PHOSPHOGLYCERIDES, CARDIOLIPINS
PHOSPHATIDYL SERINE
SEE PHOSPHOLIPIDS, PHOSPHOGLYCERIDES, PHOSPHATIDYL
SERINE
PHOSPHATURIA
SEE CALCIUM (MINERAL) IMBALANCES. PHOSPHORUS
IMBAUNCE
PHOSPHOARYLS
** ROlHL-11418-09 Poly-diaminophosphazenes
PHOSPHOCREATINE
SEE AMINO ACIDS, CREATINE PHOSPHATE
PHOSPHODIESTERASE INHIBITORS
SEE ENZYME INHIBITORS, PHOSPHODIESTERASE INHIBITORS
PHOSPHODIESTERASES
SEE ALSO NUCLEASES
SEE ALSO NUCLEASES, CYCLIC NUCLEOTIDE
PHOSPHODIESTERASE
SEE ALSO PHOSPHOLIPASE
POlHL-06285-18 0186 Cardiovascular-respiratory
physiology and biochemistry - Leukocyte hormone receptors
and cyclic nucleotides (tissue culture)
POlHL-12738-10 0134 Physiologic pharmacology and its
clinical applications - Adenylate cyclase and cAMP
phosphodiesterase in cardiac development (dogs)
ROlHL-12740-10 Hypocholesterolemic agents-
Stereochemistry (rats)
ROlHL-15002-07 Biochemical pharmacology of guanylate
cyclase in lung (cattle, rats)
ROlHL-15696-06 Mechanism and role of cyclic GMP in
heart (animals)
ROlHL-16233-05 Molecular cardiology of MDP-induced left
ventricular failure (dogs)
ROlHL-1751604 Role of androgen as a risk factor in
atherogenesis (human, animals)
P50HL-183 18-03 0015 Pathogenesis and complications of
hypertension - Cultured smooth muscle cells and
microvessel metabolism (mammals)
PHO
POIML 18827 0? 0005 Platelet veiiel wall interaclioni in
thrombogenesis Plalelet veiMl wall inl*racllORt in
thrombogenesis (human)
ROIHL 1893/ 03 Cyclic nucleotides and calcium in
platelets (human)
ROIHI 1902/ 03 Calcium and cyclic AMP in causation of
hypertension (rats)
ROIHL 19057 03 Catecholamines and cyclic AMP in
cardiovascular system (rats, dogs)
ROIHL 2078201
(rats, dogs)
ROIHL 209560?
human platelets
R23HL 2132002
endothelium
R23HL 21413-02
Coronary flow regulation by adenosine
Early events following stimulation of
Cyclic nucleotide metabolism in vascular
Structure and function of platelet
calcium binding protein (human)
RCIHL 22502 01 Role of phosphomositides in human
platelet secretion
ROIHL 22828 01 Adenosine and catecholamine interaction
in the heart (rats)
PHOSPHOFRUCTOKINASE
SEE PHOSPHOTRANSFERASES, ATP:DFRUCT0SE-6 PHOSPHATE
1 PHOSPHOTRANSFERASE
PHOSPHOGLUCONATE DEHYDROGENASE
SEE OXIDOREDUCTASES, PHOSPHOGLUCONATE
DEHYDROGENASE
PHOSPHOGLUCONATE PATHWAY
SEE PENTOSE PATHWAYS, HEXOSE MONOPHOSPHATE
PATHWAY
PHOSPHOGLYCERATE KINASE
SEE PHOSPHOTRANSFERASES. ATP:D-3-PH0SPH0GLYCERATE
1 PHOSPHOTRANSFERASE
PHOSPHOGLYCERATE KINASE DEFICIENCY
SEE METABOLIC DISORDERS INBORN, PHOSPHOGLYCERATE
KINASE DEFICIENCY
PHOSPHOGLYCERIDES
SEE PHOSPHOLIPIDS, PHOSPHOGLYCERIDES
PHOSPHOGLYCEROMUTASE
SEE PHOSPHOMUTASES, PHOSPHOGLYCEROMUTASE
PHOSPHOINOSITIDES
SEE PHOSPHOLIPIDS, PHOSPHOGLYCERIDES.
PHOSPHOINOSITIDES
PHOSPHOLIPASE
POlHL-08214-15 0025 Chemical and biological properties
of lipids - Biosynthesis and biological functions of
plasmalogen (cattle)
POlHL-08214-15 0027 Chemical and biological properties
of lipids - Biological functions diol lipids (swine, rats,
plants)
POlHL-13262-07 0022 Arterial wall in atherosclerosis -
Mechanisms of platelet prostaglanoin formation
P50HL 15062-07 0007 Study of lipoproteins, artery wall.
and atherosclerosis - Physical chemistry of lipid-protein
interaction (human)
P60HL-17269-04 0018 National heart and blood vessel
research and demonstration center - Mitochondria and
energetics (rabbits, dogs)
ROlHL-19010-03 Metabolism and cell biology of lung
surfactant system (rabbits, sheep)
ROlHL-20793-02 Phospholipids and cardiac receptor
function
ROIHL 22052-01 Organization of free cholesterol in serum
lipoproteins (human, dogs)
ROlHL-23142-01 Mechanisms of membrane injury in
myocardial ischemia (dog)
PHOSPHOLIPASE, LECITHINASE A
POlHL-06285-18 0210 Cardiovascular-respiratory
physiology and biochemistry - Physicochcmical and
enzymatic studies of lung surfactant (Halobacterium)
** POlHL-06835-17 0034 Cardiovascular disease - Studies
of phospholipase A2 in serum (rats, dogs)
ROIHL- 14397-07 Hypertension-Angiotensin and
prostaglandin pharmacology (animals)
ROlHL-14890-07 Platelet prostaglandins (human, rabbits)
** P50HL-15062-07 0008 Study of lipoproteins, artery wall.
and atherosclerosis - Lipid modifying enzymes (human,
monkey)
ROlHL-15930-06 Hormonal control of lipid and lipoprotein
synthesis (rats)
POlHL-18577-03 0001 Lipoproteins-Cell surface
interactions - Structural studies of serum lipoproteins in
man and dogs
POlHL-18577-03 0003 Lipoproteins-Cell surface
interactions - Mechanism of lipid exchange in lipoproteins
and cell membranes
P50HL-1882803 0008 Speciai'zed center of research in
thrombosis - Biochemistry, physiology-Platelets and
subcellular platelet particles (human)
ROlHL-20787-02 Thromboxanes and prostaglandins-
Biochemical pharmacology (rabbits, human)
** R23HL-21116-02 Mechanisms of membrane and tissue
damage in lung (dogs, rabbits)
** R23HL-21490-02 Studies of enzymes in human platelet
membranes
(coiitd)
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
**0riented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
wmm
'<W^-
PHO
ROlHL-21628-02 Biosynthesis of lung surfactant lipid
(rabbit)
R23HL-22011-01 Adrenergic receptor cyclase system in
sensitized lung (rats, guinea pigs)
R23HL-2207501 Metabolism of arachidonic acid in blood
vessels (chickens, mammals)
ROlHL-22555-01 Structure and function of platelet
activating factor (rabbits, human)
ROlHL-2295101 Studies on the affect of vitamin E on
platelets (human, rats)
PHOSPHOLIPASE, PHOSPHATIDYLCHOLINE
CHOLINEPHOSPHOHYDROLASE
P01HL1135112 0009 Cellular and molecular
mechanisms of myocardial function Myocardial membrane
surface coat (rats, rabbits)
POlHL-12738-10 0076 Physiologic pharmacology and its
clinical applications - Pediatric cardiac electrophysiology
and pharmacology (human, dogs)
PHOSPHOLIPASE, PHOSPHATIDYLCHOLINE
PHOSPHATIDOHYDROLASE
ROlHL-16660-06 Phospholipid-cholesterol and
phospholipid-protein interactions
PHOSPHOLIPASE A
SEE PHOSPHOLIPASE, LECITHINASE A
PHOSPHOLIPASE C
SEE PHOSPHOLIPASE, PHOSPHATIDYLCHOLINE
CHOLINEPHOSPHOHYDROLASE
PHOSPHOLIPASE D
SEE PHOSPHOLIPASE, PHOSPHATIDYLCHOLINE
PHOSPHATIDOHYDROLASE
PHOSPHOLIPIDS
NOlHI-3292610
R01HL01770-26
system (rats)
** R01HL02063-23
Analysis of lipoproteins (animals)
Structural aspects of lung surfactant
Biochemistry and function of lipids and
cell membranes (human, yeast, animals)
ROlHL-02835-21 Renal transport carrier for organic
compounds (dogs, rats)
ROlHL-02986-21 Zonal renal change with potassium
deficiency (rats, human)
ROlHL'03734-18 Metabolism of arterial tissue in
atherosclerosis (rabbits)
P01HL0628518 0210 Cardiovascular-respiratory
physiology and biochemistry - Physicochemical and
enzymatic studies of lung surfactant (Halobacterium)
' POlHL-06314-17 0051 Immunologic mechanisms in
cardiovascular disease - Conformational studies of
phospholipid membranes and proteins
P01HL06835-17 0018 Cardiovascular disease - Fatty
acid concentration (rats)
■ POlHL-08214-15 0025 Chemical and biological properties
of lipids - Biosynthesis and biological functions of
plasmalogen (cattle)
POlHL-08214-15 0027 Chemical and biological properties
of lipids - Biological functions diol lipids (swine, rats,
plants)
POlHL-0821415 0040 Chemical and biological properties
of lipids - Nuclear magnetic resonance studies of lipids
RO1HL10933-13 Fat metabolism and atherosclerosis
(rabbits, cattle, human, rats)
' ROlHL-10940-13 Lipid transport (rabbits, cattle, chickens)
ROlHL-1252810 NMR relaxation of liquid crystal systems
' ROlHL-12760-09 Surface studies of membrane lipids and
proteins
R01HL12820-09 In vitro regulation of prothrombin
activation
POlHL-13262-07 0022 Arterial wall in atherosclerosis -
Mechanisms of platelet prostaglanoin formation
POlHL-13262-07 0025 Arterial wallin atherosclerosis -
Phospholipid and cholesterol esters
ROlHL-13405-09 Regulation of lipid metabolism in the
lung (rats)
ROlHL-13587-06 Synthesis of renin inhibitors and analog
phosphatides (rats)
R01HL-I3715-08 Myocardial adenyl cyclase (rats)
ROlHL-14111-07 Cholesteryl esters in membranes and
atherosclerosis (human, swine)
P50HL14147-08 0003 Specialized center of research in
thrombosis - Surface thrombogenicity and phospholipid
vesicle physical properties
P50HL14147-08 0013 Specialized center of research in
thrombosis - Mathematical models of blood coagulation
kinetics
P50HL14147-08 0014 Specialized center of research in
thrombosis - Theoretical models for electrostatic effects in
blood clot formation
P50HL-14147-08 0015 Specialized center of research in
thrombosis - Charge related properties of phospholipid
surfaces in monolayers and vesicles
P50HL-I4214-07 0022 Newborn lung center for hyaline
membrane disease - Functional integrity of surfactant
system-Hyaline membrane disease (lamb, rat)
P50HL14230-07 0092 A/S SCOR -Lipids, atherosclerosis
and thrombosis • Tissue lipids -Cell culture studies
(human)
P50HL-14236-05 0008 Prevention of premature
arteriosclerosis - Lipoproteins of cell membranes (human)
412
ROlHL-14397-07 Hypertension -Angiotensin and
prostaglandin pharmacology (animals)
R01HL14820-07 Factors affecting physiology of biological
membranes (human)
P50HL-15061-07 0002 Response of lung to injury ■
Oxidative metabolism, phospholipid synthesis, and response
to toxins (rats)
Study of lipoproteins, artery wall,
Physical chemistry of lipid-protein
P50HL-1 506207 0007
and atherosclerosis
interaction (human)
P50HL15062-07 0021
and atherosclerosis
Study of lipoproteins, artery wall.
Core laboratories
ROlHL-1547805 Lipid flux and collagen synthesis in
atherosclerosis (rabbits)
ROIHLI 5528-05 Renin kinetics in hypertensive and
uremic plasma (human, dogs)
ROlHL-15646-03 Lipid studies in vascular smooth muscle
cells (human, monkeys)
R0IHL1605906 Structure and function of serum
lipoproteins (cattle, human)
ROlHL-16101-05 Protein-lipid interaction (bacteria,
models)
P01HL161 17-05 0003 Ion movements and membranes in
cardiovascular control - Fast kinetic study of calcium
membrane interactions
P01HL1613705 0013 Alveolar biology ■ Development and
pathology of surfactant -Formation of alveolar (rabbits.
sheep)
ROlHL-16318-21 Biochemistry and pharmacology of Na-K
transport
P01HL-16607-05 0001 Calcium ion and control of
cardiovascular function - Bilayer lipid membranes,
antibiotic probes, and SR function
R01HL16628-05 Regulation of lipid metabolism (rats)
' ROlHL-1666006 Phospholipid-cholesterol and
phospholipid-protein interactions
POlHL-16851-04 0001 Human red cell membrane in
health and disease ■ Rheology of erythrocyte membrane
(human, amphiuma)
P60HL-17269-04 0014 National heart and blood vessel
research and demonstration center - Physio-chemical nature
of lipid deposits in arterial wall (human)
P60HL1 7269-04 0017 National heart and blood vessel
research and demonstration center - Cell membrane (dogs,
rabbits)
P60HL17269-04 0018 National heart and blood vessel
research and demonstration center - Mitochondria and
energetics (rabbits, dogs)
ROlHL-17332-04 Use of the gut for therapy of coronary
artery disease (mammals)
ROlHL-17559-03 Structural elucidation of heart
cytochrome-C oxidase
ROlHL-17597-05 Role of plasma lipoproteins in
atherosclerosis (swine, human)
' P50HL17648-04 0027 Study of ischemic heart disease ■
Phospholipid metabolism following cardiac injury and
repair (rat)
P01HL17812-04 0004 Thrombosis and plasma proteins ■
Serum-platelet interaction (human)
ROlHL-17878-04 Structural studies of the human
erythrocyte membrane
ROlHL-17898'03 Cell membranes and plasma lipoproteins
(human, swine)
ROlHL-18048-04 Dynamics of artificial and biological
membranes (human)
ROlHL-182 19-04 Regulation of cholesterol metabolism
(rats)
R01HL1824904 Isolation and identification of platelet
membrane (human)
ROlHL-18255-04 Lipid-protein interactions and calcium
transport (models)
POlHL-18574-03 0005 Lipoprotein methodology and
biomedical applications ■ Structure and function of
lipoproteins
ROlHL-1858603 Role of platelet lipids in hemostasis and
thrombosis (human)
ROlHL-18623-12 Physical chemistry of biologically active
lipids (bacteria, plant, cattle, human)
P01HL-18645-03 0001 Biology of the artery wall and
atherosclerosis ■ Primate arterial smooth muscle and
atherosclerosis
POlHL-18708-03 0003 Oxygen, energy and contractility in
cardiac tissue - Structural-functional studies on cytochrome
c oxidase
P01HL18708-03 0004 Oxygen, energy and contractility in
cardiac tissue - Structural-functional studies on
sarcoplasmic reticulum (rabbits)
P01HL18827-02 0001 Platelet vessel wall interactions in
thrombogenesis - Role of endothelial cells in the production
of thrombi (human, cattle)
POlHL-18827-02 0003 Platelet vessel wall interactions in
thrombogenesis - Tumor cell and platelets in
thrombogenesis and metastasis (human, animals)
ROlHL-1885203 Biochemical studies on the blood
coagulation process (human, cattle)
ROlHL-18938-03 Pulmonary fatty acid and phospholipid
metabolism (rats)
P50HL-19185-02 0001 Pulmonary SCOR-Neonatal
respiratory distress syndromes ■ Sites of synthesis.
secretion and structure of surface active material (rat)
PHO
P50HL-1918502 0002 Pulmonary SCOR-Neonatal
respiratory distress syndromes ■ Biochemistry.
ultrastructure-Pulmonary surface active material (human,
animal)
P50HL-1918702 0002 Pediatric pulmonary SCOR -Hyaline
membrane disease - Hyaline membrane disease-Alterations
in surface active material (monkeys)
P50HL-19187-02 0003 Pediatric pulmonary SCOR-Hyaline
membrane disease - Hyaline membrane disease-
Ultrastructure studies (monkey)
P50HL-19187-02 0004 Pediatric pulmonary SCOR-Hyaline
membrane disease - Hyaline membrane disease-Surface
active material, lamellar bodies (mice, rats)
P50HL19190-02 0003 Pulmonary SCOR-Pathophysiology,
management of IRDS Type II cells-Regulation and
differentiation (rat)
R01HL19282-03
factor X
ROlHL-19392-03
Regulation of the activation of human
Spectroscopic studies of respiratory
metalloproteins
ROIHL 19459-03 Dynamics of atherogenesis and
lipoprotein formation (human, rabbit)
R23HL-19605-01 Lipid requirement of the lung mono-
oxygenase system (rabbits)
ROIHL 1967602 Physico-chemical interactions in
pulmonary surfactant
POlHL-19737 02 0001 Cellular and molecular aspects of
respiratory physiology - Fatty acid metabohsm in type II
alveolar cells (rats)
ROlHL-19752-03 Phospholipid synthesis by fetal lung in
organ culture (rats)
ROlHL-19982-02 Blood coagulation -Protein-metal ion-lipid
interactions
ROlHL-20161-02 Role of gamma-carboxyglutamic acid in
blood coagulation (human, cattle)
ROlHL-20189-01 Effects of renin on atherogenesis
(rabbits)
ROlHL-20303-03 Cholesterol distribution in erythrocyte
membrane (human, animals)
ROlHL-20350-02 Ciystal structure of lipids -Cholesterol
ROlHL-20622-02 Pulmonary uptake and accumulation of
drugs (rabbits, rats)
ROlHL-20787-02 Thromboxanes and prostaglandins-
Biochemical pharmacology (rabbits, human)
ROIHL-20793-02
function
ROlHL-21008-02
Phospholipids and cardiac receptor
Effect of pollutants on organotypic lung
Phospholipid exchange proteins in lung
Structure-function relationships of human
cultures (rats)
ROlHL-2 1176-02
tissue (lambs)
R23HL-21208-02
factor VIII
R01HL-2124e-02 Roles of cholesterol and Its metabolic
regulation (CHO cell mutants)
ROlHL-21460-02 Lipoproteins, hemostasis and
atherosclerosis (human, rabbits)
ROlHL-2 1543-02 Structure-function relation of blood
clotting proteins (rabbits)
ROlHL-21975-01 Studies on normal and abnormal factor
IX (human, dogs, cows)
R23HL-22011-01 Adrenergic receptor cyclase system in
sensitized lung (rats, guinea pigs)
ROlHL-22039-02 Ion transport in cardiac muscle (dogs,
rodents, cattle)
ROlHL-22052-01 Organization of free cholesterol in serum
lipoproteins (human, dogs)
ROlHL-22219-01 Prostacyclin and peroxides in blood and
membrane disease
ROlHL-22570-01 Interactions of sterols in biological
systems (human)
POlHL-22633-01 0003 Cellular and molecular biology of
lipoprotein metabolism - Sterol metabolism in platelets and
megakaryocytes (human, rabbits, guinea pigs)
ROlHL-22682-01 Structure and function of high density
lipoprotein (human, rat)
ROlHL-22771-01 Thrombogenic phospholipid surfaces
(cattle)
ROlHL-22813-01 Palmitylcarnitine inhibition of ion pumps
in ischemia (dogs)
ROlHL-22883-01 Lung epithelial cell interactions in vitro
R23HL-22895-01 Smoke inhalation-Biochemical and
cellular responses (rabbits, bacteria)
inetics of prothrombin activation
Bulk-surface distribution of cholesteryl
Membrane biochemistry of RH antigens
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level
•'Oriented significantly to above subject
ROlHL-22955-01
ROlHL-23003-01
esters
ROlHL-23108-01
(human)
ROlHL-23392-01 Membrane binding and transport of
calcium and potassium ionophores
R01HL-23618-0I Substrate metabolism in isolated
myocytes in shock (dogs, rats, guinea pigs)
ROlHL-23981-01 Acute alveolar injury (dogs)
PHOSPHOLIPIDS, GLYCEROPHOSPHORIC ESTERS,
GLYCEROPHOSPHORYLCHOLINE
" ROIHL- 19669-03 Lung organ culture and surfactant
biosynthesis (adult and fetal rats)
PHOSPHOLIPIDS, LYSOPHOSPHOLIPIDS
SEE ALSO PHOSPHOLIPIDS, PHOSPHOGLYCERIDES.
LYSOLECITHIN
" ROlHL-19148-03 Myocardial organelle lipid structure and
function (dog. rat)
(contd)
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
.^sssss^ssr
PHO
ROIHI 23142 01 Mechanisms ol niembiane in|uiy in
myocardial ischtmia (dog)
ROIHI 23166 01 Pathology ol mitochondria m ischemic
myocaidium (rats, cattle}
PHOSPHOLIPIDS, PHOSPHOGIYCERIDES
ROIHI 02063 23 Biochemistry and function ot lipidsand
cell membranes (human, yeast, animals)
ROIHL 13405 09 Regulation ot lipid metabolism in the
lung (rats)
R01H113587 06 Synthesis ot renin inhibitors and analog
phosphatides (rats)
PHOSPHOLIPIDS, PHOSPHOGLYCERIDES,
CARDIOLIPINS
PbOHL W648 04 0027 Study ot ischemic heart disease •
Phospholipid metabolism tollowing cardiac iniury and
repair (rat)
PHOSPHOLIPIDS, PHOSPHOGLYCERIDES,
LECITHINS
ROIHL 02835 21 Renal transport carrier tor organic
compounds (dogs, rats)
P01HL0628518 0208 Cardiovascular-respiratory
physiology and biochemistry ■ Composition, properties and
turnover of pulmonary surfactant (human, animals)
P01HL06285 18 0209 Cardiovascular respiratory
physiology and biochemistry - Metabolic studies of isolated
lung cells (human, animals)
POlHL-06835 17 0015 Cardiovascular disease • Plasma
cholesterol esterification in canine atherosclerosis
** P01HL0789615 0058 Environmental biomedical research
program - Lung synthesis of disaturated
phosphatidylcholine (rats. dogs, bats)
P01HL08214-15 0040 Chemical and biological properties
of lipids - Nuclear magnetic resonance studies of lipids
R01HL12650-08 Environmental pathobiology of the lung
(hamsters, rats)
P01HL13262-07 0022 Arterial wall in atherosclerosis -
Mechanisms of platelet prostaglanoin formation
P50HL-14147-08 0003 Specialized center of research in
thrombosis - Surface thrombogeniclty and phospholipid
vesicle physical properties
P50HL14214-07 0015 Newborn lung center for hyaline
membrane disease ■ Hormone effect on cyclic nucleotide
lipid synthesis In developing lung (animal)
P50HL-14214-07 0021 Newborn lung center for hyaline
membrane disease ■ Development of surtactant system-
Surfactant production and release (rat, rabbit)
P50HL-15062-07 0007 Study of lipoproteins, artery wall,
and atherosclerosis - Physical chemistry of llpid-protein
interaction (human)
** ROlHL-1527306 Metabolism of pulmonary surtactant
(human, rats)
R01HL16660-06 Phospholipld-cholesterol and
phosphollpid'Protein Interactions
ROlHL-16725-03 Physiological regulation of pulmonary
surfactant (dogs, rats)
P01HL16748-05 0004 Cellular and Immunological basis
of pulmonary diseases - Cellular and immunological
processes In pulmonary defense systems
ROlHL-16807-02 Lipid structure of normal and
hyperllpoproteins (human)
P60HL17269-04 0009 National heart and blood vessel
research and demonstration center - Physical methods
laboratory (high density lipoproteins)
P60HL-17269-04 0013 National heart and blood vessel
research and demonstration center - Peptide synthesis
laboratory (human)
P60HL-1726904 0015 National heart and blood vessel
research and demonstration center ■ Lipoprotein
metabolism laboratory (human)
** P60HL-17269-04 0046 National heart and blood vessel
research and demonstration center Nuclear magnetic
resonance laboratory
ROlHL-17332-04 Use of the gut for therapy of coronary
artery disease (mammals)
R01HL17576-04 Role of sphingomyelin In biomembranes
and bllayers (rats, other mammals)
ROlHL-17719-03 Lung injury, substrate utilization, oxygen
toxicity (rats, rabbits, dogs)
ROlHL-1862312 Physical chemistry of biologically active
lipids (bacteria, plant, cattle, human)
R01HL1901003 Metabolism and cell biology of lung
surfactant system (rabbits, sheep)
P50HL-1918502 0001 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Sites ot synthesis,
secretion and structure of surface active material (rat)
P50HL1918702 0002 Pediatric pulmonary SCOR -Hyaline
membrane disease - Hyaline membrane disease -Alterations
In surface active material (monkeys)
ROlHL-19485-03 Calcium uptake by normal and failed
cardiac ATPase (dogs)
ROlHL-19676-02 Physico-chemical interactions In
pulmonary surfactant
POlHL-19737-02 0003 Cellular and molecular aspects of
respiratory physiology - Cortlsol-dependent alterations In
lung type II cells (rats)
ROlHL-21008-02 Effect of pollutants on organotypic lung
cultures (rats)
** ROIHI -21176-02 Phospholipid exchange proteins In lung
tissue (lambs)
413
*• R23HL 21251 01 Metabolism ol neutral lipids in the
pulmonary alveolus (rabbits)
•• ROIHL 21628 02 Biosynthesis ol lung surfactant lipid
(rabbit)
•• ROIHI 22500 01 Conversion of choline to
phosphatidylcholine in lung (rabbits, pigs)
ROIHL 22682 01 Structure and (unction of high density
lipoprotein (human, rat)
ROIHL 23969 01 Surfactant synthesis by type II cells in
vitro (rats)
PHOSPHOLIPIDS, PHOSPHOGLYCERIDES,
LYSOLECITHIN
ROIHL 09744 14 Experimental vascular sclerosis
(monkeys, rabbits)
P01HL12157 11 0037
membrane ion transport
cells in tissue culture
P01HL12157 11 0055
membrane Ion transport
Functions and mechanisms of cell
Developing structure of heart
Functions and mechanisms of cell
Growth and development of
synthetic strand heart cells in culture (chick embryo)
ROIHL 1325608 Ammo acid transport by red cell
membranes (pigeons)
ROIHL 13567 06 Ion transport across cell membranes
(human)
P60HL- 17269-04 0009 National heart and blood vessel
research and demonstration center ■ Physical methods
laboratory (high density lipoproteins)
ROlHL-17597-05 Role of plasma lipoproteins in
atherosclerosis (swine, human)
ROIHL 1893803 Pulmonary fatty acid and phospholipid
metabolism (rats)
PHOSPHOLIPIDS, PHOSPHOGLYCERIDES,
PHOSPHATIDIC ACIDS
POlHL-082 14-15 0030 Chemical and biological properties
of lipids Fatty acid biosynthesis in plant cell cultures and
in plants
PHOSPHOLIPIDS, PHOSPHOGLYCERIDES,
PHOSPHATIDYL ETHANOLAMINE
ROlHL-02063-23 Biochemistry and function of lipids and
cell membranes (human, yeast, animals)
P50HL-14147-08 0003 Specialized center of research in
thrombosis - Surface thrombogeniclty and phospholipid
vesicle physical properties
ROlHL-17878-04 Structural studies ot the human
erythrocyte membrane
PHOSPHOLIPIDS, PHOSPHOGLYCERIDES,
PHOSPHATIDYL SERINE
ROlHL-02063-23 Biochemistry and function of lipids and
cell membranes (human, yeast, animals)
** POlHL-031 74-23 0009 Mechanisms of acute vascular
reaction to Injury • Mast cell lipid Interaction (human, rats)
" ROlHL-13715-08 Myocardial adenyl cyclase (rats)
P50HL-14147-08 0003 Specialized center of research In
thrombosis - Surface thrombogeniclty and phospholipid
vesicle physical properties
ROlHL-18272-03 Heart adenyl cyclase complex (beef
heart)
ROlHL-204 11-03 Platelet fatty acid metabolism in
diabetes (rat, rabbit, guinea pig)
PHOSPHOLIPIDS, PHOSPHOGLYCERIDES,
PHOSPHOINOSITIDES
POlHL-13262-07 0022 Arterial wall in atherosclerosis -
Mechanisms of platelet prostaglanoin formation
ROlHL-137 15-08 Myocardial adenyl cyclase (rats)
** ROlHL-15567-05 Cardiovascular phosphoinositide
metabolism (rats)
ROlHL-18272-03 Heart adenyl cyclase complex (beef
heart)
** ROlHL-2250201 Role of phospholnosltides in human
platelet secretion
PHOSPHOLIPIDS, PHOSPHOGLYCERIDES,
PLASMALOGENS
** POlHL-082 14-15 0025 Chemical and biological properties
of lipids • Biosynthesis and biological functions of
plasmalogen (cattle)
POlHL-082 14-15 0040 Chemical and biological properties
of lipids - Nuclear magnetic resonance studies of lipids
PHOSPHOLIPIDS, PHOSPHOSPHINGOLIPIDS,
SPHINGOMYELINS
ROlHL-02835-21 Renal transport carrier for organic
compounds (dogs, rats)
ROlHL-09744-14 Experimental vascular sclerosis
(monkeys, rabbits)
P50HL-1 5062-07 0007 Study of lipoproteins, artery wall,
and atherosclerosis - Physical chemistry of lipid-proteln
Interaction (human)
P60HL-17269-04 0009 National heart and blood vessel
research and demonstration center - Physical methods
laboratory (high density lipoproteins)
** R01HL17576-04 Role ot sphingomyelin In biomembranes
and bllayers (rats, other mammals)
P50HL-191 87-02 0002 Pediatric pulmonary SCOR -Hyaline
membrane disease - Hyaline membrane disease -Alterations
In surface active material (monkeys)
ROlHL-23003-01 Bulk-surface distribution of cholesteryl
esters
PHO
PHOSPHOMONOESTERASES, ACID
PHOSPHATASE
ROIHI 13885 08 0008 Cy«lic (ibraiii and pulmonary
disease Pscudomonas specific activation of alveolar
macrophages (human, rabbits)
POIHL 16/48 05 0006 Cellular and immunological bails
of pulmonary diseases Sarcoidosis Studies with bronchial
lavage (human)
P50HL 17669 04 0011 Ischemic heart disease center
(SCOR) Lysosomal function and lysosomal enzymes in
normal and ischemic heart (rabbit)
ROIHL 1907203 Modification of tissue injury in
myocardial infarction (dogs, human)
P50HL 19185 02 0002 Pulmonary SCOR Neonatal
respiratory distress syndromes Biochemistry.
ultrastructure Pulmonary surface active material (human.
animal)
ROIHL 2010403 Pulmonary granulomatous inflammations
(mice)
PHOSPHOMONOESTERASES, ALKALINE
PHOSPHATASE
SEE ALSO METABOLIC DISORDERS INBORN.
HYPOPHOSPHATASIA
P60HL 16008 06 0015 Wayne State University
comprehensive sickle cell center - Trace elements in sickle
cell disease (human)
P50HL-19171 02 0008 Pulmonary SCOR Lung injury by
childhood infections Host parasite interaction-Electron
microscopy, radioautography. histochemistry
R01HL2103001 Calcium regulation and hypertension
(rats)
PHOSPHOMONOESTERASES, FRUCTOSE 1,6-
DIPHOSPHATASE
POlHL-12157-11 0051 Functions and mechanisms of cell
membrane Ion transport Electron transport In the red cell
membrane (human, guinea pigs)
ROlHL-17976-18 Chemical agents and heart glycolytic
enzymes (sheep)
PHOSPHOMONOESTERASES, GLUCOSE-6-
PHOSPHATASES
SEE ALSO METABOLIC DISORDERS INBORN, GLYCOGENOSIS
ROlHL-13885-08 0008 Cystic fibrosis and pulmonary
disease - Pseudomonas specific activation of alveolar
macrophages (human, rabbits)
PHOSPHOMONOESTERASES, S'-NUCLEOTIDASE
ROlHL-17759-03 Studies of myocardial reactive hyperemia
(dogs, human)
ROlHL-1815704 Subcellular events In atherosclerosis
(human, rabbits, calves)
** ROlHL-22486-01 Enzyme regulation In cultured arterial
cells (swine)
PHOSPHOMUTASES, PHOSPHOGLYCEROMUTASE
ROlHL-16647-05 Studies on the control of sickle cell crisis
(human)
PHOSPHONATES
R01HL12745-10 Enzymes and inhibitors of cholesterol
biosynthesis (rats, human, swine)
PHOSPHONATES, DIPHOSPHONATES
** P50HL-14230-07 0094 A/S SCOR-Liplds, atherosclerosis
and thrombosis - Studies of atherosclerosis and regression
(monkeys)
** P60HL-15999-05 0021 Miami comprehensive sickle cell
center - DIphosphonales-Erythrocyte calcium loading,
maturation (human, chick embryo)
PHOSPHOPROTEIN KINASES
SEE PHOSPHOTRANSFERASES. ATP:PHOSPHORYLASE
PHOSPHOTRANSFERASE
SEE PHOSPHOTRANSFERASES, ATPPROTEIN
PHOSPHOTRANSFERASE
PHOSPHOPROTEINS
ROlHL-15930-06
synthesis (rats)
ROlHL-21030-01
(rats)
** ROlHL-21995-01
effects
** ROlHL-23990-01
Inotropic responses
PHOSPHORAMIDES
ROlHL-18679-04 Synthetic protease Inhibitors
PHOSPHORUS
** ROlHL-22080-01 Phosphorus NMR studies on cardiac
tissue (rats, rabbits)
PHOSPHORUS BALANCE (METABOLISM)
SEE CALCIUM (MINERAL) BAUNCE, PHOSPHORUS BALANCE
(METABOLISM)
PHOSPHORUS COMPOUNDS (GENERAL)
ROlHL-13531-06 Coboglobins -Cobalt substituted myo- and
hemoglobins
PHOSPHORUS IMBALANCE
SEE CALCIUM (MINERAL) IMBALANCES. PHOSPHORUS
IMBALANCE
(contd)
Hormonal control of lipid and lipoprotein
Calcium regulation and hypertension
Protein phosphorylation and adrenergic
Role of phosphoprotein In cardiac
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
**0riented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
mmm
PHO
PHOSPHORYLASE, MUSCLE A AND B
SEE GLYCOSYLTRANSFERASES, 1,4-ALPHA-D-
GLUCAN:ORTHOPHOSPHATE ALPHA-
GLUCOSYLTRANSFERASE
PHOSPHORYLASE B KINASE
SEE PHOSPHOTRANSFERASES, ATP:PROTEIN
PHOSPHOTRANSFERASE
PHOSPHORYLASE KINASE
SEE PHOSPHOTRANSFERASES, ATPiPHOSPHORYLASE
PHOSPHOTRANSFERASE
PHOSPHORYLASES
SEE ALSO PHOSPHOTRANSFERASES
POlHL-12373-10 0006 Cardiopulmonary physiology and
pathophysiology • Fatty acid metabolism -Regulation,
implications (human, mammals, birds)
POlHL-12373-10 0012 Cardiopulmonary physiology and
pathophysiology • Biochemistry of the sympathetic nervous
system (rats, rabbits, pigeons)
R01HL-17729-D4 Stimulus-response coupling In platelets
(human)
ROlHL-17907-04 8rain regulation of cardiac arrhythmia
(pigs, cats, rats)
R01HL-18259-03 Controlled intratissue release of
prostaglandins
POlHL-22619-01 0009 Cellular mechanisms of heart
failure - Sarcoplasmic reticulum In cardiac, skeletal and
smooth muscle (rabbits, dogs)
R01HL-23128-01 Cardiac contractility-Ischemia and
hypoxia (rabbits, rats)
** R01HL-23iei-01 0003 Biology of myocardial Ischemia -
Phosphorylase coupling to myocardial sarcoplasmic
reticulum (dog)
PHOSPHORYLATION
SEE ALSO OXIDATIVE PHOSPHORYLATION
ROlHL-01974-24 Ion-pump In the erythrocyte (rabbits,
guinea pigs)
R01HL-10018-11 Effect of aging on beating heart cells in
culture (rats)
POlHL-1 1351-12 0004 Cellular and molecular
mechanisms of myocardial function ■ Molecular
mechanisms of contractile function and differentiation
(animals)
ROlHL-13029-09 Metabolic regulation of sugar transport
(pigeons, rats)
ROlHL-13302-09
liver (rats)
R01HL13630-08
(cattle)
P30HL14217-08 0058 Specialized center of research In
thrombosis - Mechanisms of induction and Inhibition of
platelet reaction (human, pig)
POlHL-1438807 0172 Regulation of the circulation In
pathological states - cAMP-dependent protein kinase from
heart and vascular smooth muscle (guinea pigs)
ROlHL-14990-07 Lipid transport in avian species
(chickens)
P60HL-15I57-07 0009 Comprehensive center for sickle
cell disease - Red cell membrane alterations during
sickling (human)
Pe0HL-lS157-07 0018 Comprehensive center for sickle
cell disease - Red blood cell membrane physiology in sickle
cell anemia (human)
ROlHL-15391-07 EPR studies on rotational motion of
myosin and actin
ROlHL-15692-07 Force and speed In skeletal and cardiac
muscle
R01HL-I5793-06 Molecular aspects of erythrocyte
membrane resealing (human)
ROlHL-15980-Oe Reactions of hemeproteins and oxygen
(cattle)
R01HL-1598S-06 Metabolic and hormonal control of
cardiac contraction
P60HL- 16008-06 0018 Wayne State University
comprehensive sickle cell center - Hemoglobin S and RBC
membranes -Pathogenesis of irreversibly sickled cells
P01HL-ie251-06 0008 Membrane-bound enzymes In heart
and other tissues ■ Iron-sulfur centers and phospholipids
modulation of succinate dehydrogenase
ROlHL-16647-05 Studies on the control of sickle cell crisis
(human)
R01HL-16938-05 Effect of physical forces on blood (dogs,
human)
** P50HL-17682-04 0024 Study of ischemic heart disease -
Phosphorylation of cardiac contractile proteins during
Ischemia (rat, guinea pig)
ROlHL-1 7976-18 Chemical agents and heart glycolytic
enzymes (sheep)
R0IHL-18094-04
(rats)
ROIHL-18148-04
ROlHL-18280-03
metabolism (rats)
ROlHL-18551-03 Spectrin, actin, lipid and red cell
membrane structure
ROlHL-18660-03 Neurotransmitter receptors In human
erythrocytes
R01HL19148-03 Myocardial organelle lipid structure and
function (dog, rat)
Uptake and metabolism of lipids by the
Control of glycogen synthesis In heart
Regulation of cholesterol biosynthesis
Adrenal catecholamine secretion
Regulation of cardiac contractility and
414
ROlHL-19181-02 Regulation of heart cAMP-dependent
protein kinase (rodents)
ROlHL-19323-03 Studies of platelet microtubule protein
ROlHL-20300-02 Histone H5 and avian erythropoiesis
(chickens, rabbits)
R23HL-2 1128-02 ATP utilization in platelet contractile
mechanisms (human, rabbits)
ROlHL-21469-01 Active transport and effect of CAOO in
sickle cell (human)
R23HL-21488-01 Myosin-linked regulation In vertebrate
smooth muscle (calf aorta)
R01HL-21820-01 Regulatory role of myosin in cardiac
hypertrophy (dogs)
ROlHL-21850-01 Calcium transport in the hypertrophied
myocardium (rats, animals)
Protein phosphorylation and adrenergic
Modulation of calcium control of cardiac
Phosphorylation of myocardial protein
Biochemistry of contractile proteins
A study of the regulation of myocardial
** ROlHL-21995-01
effects
ROlHL-22231-02
myofibrils (rats)
** ROlHL-22264-01 Regulation of contraction in vascular
smooth muscle (dogs)
ROlHL-22401-01 Regulation of tension and active state in
the heart
POlHL-226 19-01 0001 Cellular mechanisms of heart
failure - Cell membrane isolation and reconstitution (dogs,
lambs)
POlHL-22619-01 0004 Cellular mechanisms of heart
failure - Mechanism of action of Na, K-ATPase (sheep,
cattle)
** POlHL-226 19-01 0006 Cellular mechanisms of heart
failure - Phosphorylation of contractile proteins in cardiac
muscle contraction (dogs, rabb
POlHL-22619-01 0008 Cellular mechanisms of heart
failure - Molecular mechanisms and differential contractile
responsiveness in VSM (dogs)
ROlHL-22845-01 Response of cardiac myosin to
hypertrophic stress (rabbits)
ROlHL-23249-01 Actin-myosin interaction in pulmonary
smooth muscle (cattle)
** ROlHL-23587-01
(guinea pigs)
R01HL-236150I
(chicken, rabbit)
ROlHL-2362601
hypertrophy (rats)
" R01HL-23990-01 Role of phosphoprotein in cardiac
Inotropic responses
PHOSPHORYLCHOLINE
SEE ALSO PHOSPHOLIPIDS, GLYCEROPHOSPHORIC ESTERS,
GLYCEROPHOSPHORYLCHOLINE
SEE ALSO PHOSPHOLIPIDS, PHOSPHOGLYCERIOES, LECITHINS
SEE ALSO PHOSPHOLIPIDS, PHOSPHOGLYCERIOES,
LYSOLECITHIN
SEE ALSO PHOSPHOLIPIDS, PHOSPHOGLYCERIOES,
PUSMALOGENS
SEE ALSO PHOSPHOLIPIDS, PHOSPHOSPHINGOLIPIDS,
SPHINGOMYELINS
POlHL-082 14-15 0027 Chemical and biological properties
of lipids - Biological functions diol lipids (swine, rats,
plants)
PHOSPHOSERINE
SEE AMINO ACIDS, PHOSPHOSERINE
PHOSPHOTRANSFERASES
ROlHL-13399-16 Heme protein structure and function
(human, horse, plants, bacteria)
** ROlHL-15567-05 Cardiovascular phosphoinositide
metabolism (rats)
** ROlHL-16101-05 Protein-lipid interaction (bacteria,
models)
POlHL-19737-02 0003 Cellular and molecular aspects of
respiratory physiology - Cortisol-dependent alterations in
lung type II cells (rats)
** ROlHL-20300-02 Histone H5 and avian erythropoiesis
(chickens, rabbits)
R23HL-214 13-02 Structure and function of platelet
calcium-binding protein (human)
PHOSPHOTRANSFERASES, ATP:AMP
PHOSPHOTRANSFERASE
ROlHL-12690-09 Systemic and local vascular adjustment
in shock (monkeys, cats)
P50HL-17651-04 0039 Ischemic heart disease specialized
center of research - Measurement and prediction of infarct
size (human, dog)
ROlHL-20878-02 Cellular aspects of lung injury (rats,
rabbits)
ROlHL-22538-01 Myosin as a multi-enzyme complex (dogs,
rabbits)
PHOSPHOTRANSFERASES, ATP:CREATINE
PHOSPHOTRANSFERASE
** POlHL-06285-18 0164 Cardiovascular-resplratoiy
physiology and biochemistry - CPK MB Isoenzyme
concentration to quantify infarct size (human, animals)
POlHL-06285-18 0173 Cardiovascular-respiratory
physiology and biochemistry - Skeletal and cardiac muscle
function
POlHL-063 12-17 0013 Surgical cardiology - Aortocoronary
vein bypass grafting (human)
POlHL-063 12-17 0053 Surgical cardiology ■ Enzyme
pattern following cardiac surgery (human)
*Eicludes routine methodotogy OR covers only general projects which preclude indexing at the specific level
•"Oriented significantly to above subject.
PHO
POlHL-07896-15 0032 Environmental biomedical research
program - Fluorometry study of brain exposed to hyperbaric
oxygen (dogs, cats)
POlHL-07896-15 0049 Environmental biomedical research
program - Effects of hyperbaric oxygen and pressure on
cerebral enzymes (rats)
POlHL-07896-15 0062 Environmental biomedical research
program - Vectorcardiograms during diving (human, dogs)
POlHL-1 1351-12 0015 Cellular and molecular
mechanisms of myocardial function - Effects of hypoxia
and ischemia on Ion exchange and heart function (rabbits)
ROlHL-11876-11 Regional myocardial blood flow and
metabolism (dogs, swine)
POlHL-12157-11 0055 Functions and mechanisms of cell
membrane ion transport - Growth and development of
synthetic strand heart cells in culture (chick embryo)
POlHL-12373-10 0001 Cardiopulmonary physiology and
pathophysiology - Mechanics of myocardial contraction
(dogs, rats, swine)
ROlHL-15522-06 Influence of mannltol on ischemia
cardiac muscle (dogs, cats, rats)
ROlHL-16254-05 Pathogenesis of bubble and clot
formation (fish)
P50HL-17646-04 0002 Study of ischemic heart disease -
Core data management
** P50HL- 17646-04 0005 Study of Ischemic heart disease -
Biochemical markers and mediators of myocardial Ischemic
injury
** P50HL-17646-04 0006 Study of ischemic heart disease -
Mathematical models for predicting infarct size using CPK
and other markers
" P50HL- 17646-04 0007 Study of ischemic heart disease -
Prediction of myocardial Ischemic injury by analysis of
plasma CPK isoenzymes
P50HL-17648-04 0023 Study of ischemic heart disease -
Chemical mediators of Inflammation In acute myocardial
infarction (mammals)
P50HL-17651-04 0036 Ischemic heart disease specialized
center of research - Core facilities -Cardiovascular
pathology (human, dog)
** P50HL-1 7651-04 0039 Ischemic heart disease specialized
center of research - Measurement and prediction of infarct
size (human, dog)
** P50HL-17665-04 0008 Study of Ischemic heart disease •
Core laboratory-CPK Isoenzyme measurement and
myocardial necrosis evaluation
P50HL-1766704 0030 Study of ischemic heart disease ■
Computerized clinical data acquisition and processing
" P50HL-1 7667-04 0043 Study of ischemic heart disease -
Quantitation of myocardial infarct size by serial enzyme
measurements (human)
P50HL-1 7669-04 0001 Ischemic heart disease center
(SCOR) - Radioimmunoassays for CPK Isoenzyme and
myoglobin (human, dog)
P50HL-17669-04 0023 Ischemic heart disease center
(SCOR) - Patients with acute myocardial infarction and
myocardial ischemia (human)
** P50HL- 17670-04 0017 Study of ischemic heart disease -
Core enzymology laboratory (human)
" P50HL-1 7670-04 0021 Study of ischemic heart disease -
Enzymatic evaluation of acute myocardial infarction (dogs)
** P50HL-17682-04 0010 Study of ischemic heart disease -
Core clinical enzyme laboratory (human, mice, dogs, rats)
P50HL-17682-04 0018 Study of ischemic heart disease -
Biochemistry of ischemia-Heart cell and organ culture
(mice, rats, cattle)
ROlHL-17736-04 Metabolic change during cardiac
Ischemia (rats, dogs)
ROIHL- 19000-03 Irreversible myocardial injury (rats)
ROlHL-19072-03 Modification of tissue Injury in
myocardial infarction (dogs, human)
ROlHL-19537-03 Detection of myocardial injury with
ultrasound (dogs)
ROlHL-19782-02 Pharmacologic studies on the Ischemic
heart (dogs)
** ROlHL-19974-02 Psychologic-behavioral influences on
heart pathology (rats)
ROlHL-20199-02 Drug-induced alterations in infarct size
in the rat
ROlHL-20283-02 Maintenance of cellular integrity In
ischemic hearts (cats)
** POlHL-20552-02 0010 The development and regression of
cardiac hypertrophy - Energy metabolism in the
hypertrophied heart animals
" ROlHL-20658-01 Myocardial energy transport-Creative
kinase (human, cattle, dog)
ROlHL-21312-01 Sarcomere mechanics In disrupted
ventricular muscle (guinea pigs)
ROlHL-22538-01 Myosin as a multi-enzyme complex (dogs,
rabbits)
ROlHL-23970-01 Mechanisms and control of sudden
cardiac death (human, dog)
NOlHV-62960-00 Techniques to protect ischemic
myocardium and minimize infant size (human)
PHOSPHOTRANSFERASES, ATP:OIGLYCERIDE
PHOSPHOTRANSFERASE
ROlHL-21628-02 Biosynthesis of lung surfactant lipid
(rabbit)
(contd)
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
PHO
PHOSPMOTRANSKRASeS, ATP:D-FRUCTOSE-6-
PHOSPHATE 1 -PHOSPHOTRANSFERASE
•* ROIHI 179?6 18 Chemiol agents and heart glycolytic
en/ymes (sheep)
PHOSPHOTRANSFERASES, ATP:D-3-
PHOSPHOGIYCERATE 1-
PHOSPHOTRANSFERASE
ROIHL 1512507 Moleculai pathology ol genetic disoiders
in man
ROIHL 16S47 05 Studies on the control ol sickle cell crisis
(human)
PHOSPHOTRANSFERASES, ATP:PHOSPHORYLASE
PHOSPHOTRANSFERASE
POIHI 12373 10 0012 Cardiopulmonary physiology and
pathophysiology Biochemistry of the sympathetic nervous
system (rats, rabbits, pigeons)
ROIHL 13630 08 Control ot glycogen synthesis in heail
(cattle)
R01HL1828003 Regulation o( cardiac contractility and
metabolism (rats)
ROIHL 21812 02 Actions of drugs and ions on cardiac
membranes (rabbits, guinea pigs)
ROIHL 2206402 Glycogen metabolism in anoxic diabetic
myocardium (rats)
ROlHL-2316101 0003 Biology of myocardial ischemia -
Phosphorylase coupling to myocardial sarcoplasmic
reticulum (dog)
PHOSPHOTRANSFERASES, ATP:PROTEIN
PHOSPHOTRANSFERASE
P01HL0628518 0186 Cardiovasculaitespiiatory
physiology and biochemistry Leukocyte hormone receptors
and cyclic nucleotides (tissue culture)
P01HL06314-17 0055 Immunologic mechanisms in
cardiovascular disease - Genetics and cell biology
POIHL 1135112 0004 Cellular and molecular
mechanisms of myocardial function Hflolecular
mechanisms of contractile function and differentiation
(animals)
P01HL12373-10 0006 Cardiopulmonary physiology and
pathophysiology • Fatty acid metabolism-Regulation,
implications (human, mammals, birds)
ROIHL 13630-08 Control of glycogen synthesis in heart
(cattle)
ROlHL-13870-09 Control of myocardial sarcotubular
calcium stores (dogs)
" POIHL 14388-07 0172 Regulation of the circulation In
pathological states - cAMP-dependent protein kinase from
heart and vascular smooth muscle (guinea pigs)
*• ROlHL-15696-06 Mechanism and role of cyclic GMP in
heart (animals)
** ROIHL 15764-05 CAMP dependent protein kinase in
cardiac contraction (dogs)
ROlHL-15930-06 Hormonal control of lipid and lipoprotein
synthesis (rats)
ROlHL-15985-06 Metabolic and hormonal control of
cardiac contraction
P60HL-16005-05 0013 Comprehensive sickle cell center ■
Study of regulation of erythropoicsis in vitro (human, rat,
hamster, rabbit)
ROlHL-16233-05 Molecular cardiology of MDPinduced left
ventricular failure (dogs)
ROlHL-16938-05 Effect of physical forces on blood (dogs,
human)
ROlHL-18148-04 Adrenal catecholamine secretion
R01HL-18260-04 Cyclic nucleotide metabolism in lung
tissue (cattle)
ROIHL- 18280-03 Regulation of cardiac contractility and
metabolism (rats)
ROlHL-18682-03 Protein kinase and cholesterol
metabolism in aorta (rabbits)
ROlHL-18937-03 Cyclic nucleotides and calcium in
platelets (human)
ROlHL-19027-03 Calcium and cyclic AMP in causation of
hypertension (rats)
ROlHL-19057-03 Catecholamines and cyclic AMP in
cardiovascular system (rats, dogs)
** ROlHL-19181-02 Regulation of heart cAMP-dependent
protein kinase (rodents)
ROlHL-19323-03 Studies of platelet microtubule protein
ROlHL-19394-03 Biochemistry and regulation of taurine in
the heart (rats, guinea pigs, cats)
ROlHL-201 14-02 Collagen-platelet interaction and human
aorta collagen (human)
•* POlHL-20984-02 0006 Cellular mechanisms in cardiac
hypertrophy - Early biochemical aspects of cardiac
hypertrophy (rats)
R23HL-21320-02 Cyclic nucleotide metabolism in vascular
endothelium
R23HL-21421-01 Myocardial and vascular contractility and
cyclic nucleotides (cattle, rats)
ROlHL-21812-02 Actions of drugs and ions on cardiac
membranes (rabbits, guinea pigs)
ROlHL-22064-02 Glycogen metabolism in anoxic diabetic
myocardium (rats)
ROlHL-22135-01 Control of calcium fluxes across cardiac
membranes (dogs, rabbits, guinea pigs)
POlHL-22619-01 0003 Cellular mechanisms of heart
failure - Digitalis induced inotropy in myocardial ischemia
heart failure (animals)
415
POIHL 22619 01 0009 Cellular mechanisms ot heart
failure Sarcoplasmic reticulum in cardiac, skeletal and
smooth muscle (rabbits, dogs)
POIHI 22619 01 0010 Cellular mechanisms ol heart
failure Mitochondria in heart and smooth muscle (rabbits,
rats, dogs)
ROIHL 22828 01 Adenosine and catecholamine Interaction
in the heart (rats)
** R23HL 22984 01 Cyclic AMP dependent protein kinases in
hypertension (rat)
ROIHL 23161 01 0003 Biology of myocardial ischemia
Phosphorylase coupling to myocardial sarcoplasmic
reticulum (dog)
ROIHL 23587 01 Phosphorylation of myocardial protein
(guinea pigs)
ROlHL-2361501 Biochemistry of contractile proteins
(chicken, rabbit)
ROIHL 2399001 Role of phosphopiotein in cardiac
inotropic responses
PHOSPHOTRANSFERASES, ATP:THYMIDINE 5-
PHOSPHOTRANSFERASE
P60HL- 17269-04 0020 National heart and blood vessel
research and demonstration center ■ Nucleic acid and
protein metabolism in growth and development of heart
(rat)
PHOTOBIOLOGY
SEE ALSO BIOPERIODICITY, CIRCADIAN RHYTHMS
ROIHL 19488 03 Picosecond laser studies of heme-
proteins
PHOTOCHEMISTRY
POlHL-06285-18 0211 Cardiovascular-respiratory
physiology and biochemistry Purple membrane of
Halobacteria
ROIHL 12971-15 Reactions of alkoloids and their analogs
ROlHL-16471-05 Cardioactive alloyohimbines and related
indole alkaloids
ROlHL-19488-03 Picosecond laser studies of heme-
proteins
PHOTOCHEMISTRY, PHOTOLYSIS
ROlHL-09906-13 0018 Membrane transport processes in
red blood cells - Rapid photolytic release of ATP from a
protected analog -Na-K pump of RBC ghosts
PHOTOCOAGULATION THERAPY
SEE THERAPY, CAUTERY, PHOTOCOAGULATION THERAPY
PHOTOELECTRIC PLETHYSMOGRAPHY
SEE CARDIOVASCULAR DISORDERS DIAGNOSIS,
PLETHYSMOGRAPHY, PHOTOELECTRIC*
PHOTOELECTRON SPECTROMETRY
SEE CHEMISTRY, ANALYTICAL METHODS, SPECTROMETRY,
PHOTOELECTRON*
PHOTOGRAPHY
SEE OPTICS, PHOTOGRAPHY*
PHOTOLYSIS
SEE PHOTOCHEMISTRY, PHOTOLYSIS
PHOTOMICROGRAPHY
SEE OPTICS, PHOTOMICROGRAPHY*
PHOTOPERIODISM
SEE BIOPERIODICITY, CIRCADIAN RHYTHMS
PHOTORECEPTORS IN VISION
SEE EYE, PHOTORECEPTORS
PHOTOTHERAPY
POlHL-08899-14 0061 Tolerance to respiratory gases in
health and disease - Hepatic oxygenation and secretory
functions (rats, dogs)
PHRENIC NERVE
SEE NERVOUS SYSTEM, SPINAL NERVES. PHRENIC NERVE
PHYLLOQUINONE REDUCTASE
SEE OXIDOREDUCTASES, NAD(P)H DEHYDROGENASE
(QUINONE)
PHYLOGENY
SEE BIOLOGY, SYSTEMATIC, EVOLUTION AND PHYLOGENY
PHYSICAL ACTIVITY, EFFORT
SEE HEALTH, PHYSICAL ACTIVITY, EXERCISE
PHYSICAL AND/OR CHEMICAL AGENTS
INTERACTION (BIOLOGICAL AND
ECOLOGICAL)
ROlHL-1387009 Control of myocardial sarcotubular
calcium stores (dogs)
** POlHL-14388-07 0207 Regulation of the circulation in
pathological states - Brain and renin-angiotension
interaction in spontaneous hypertension (rats)
ROIHL 19488-03 Picosecond laser studies of heme-
proteins
** ROlHL-21461-01 Heme group protein interactions in
hemoproteins
ROlHL-22029-02 Bronchopulmonary resistance to bacterial
infection (mice)
PHYSICAL AND/OR CHEMICAL AGENTS
INTERACTION (BIOlOOICAl AND
ECOLOGICAL), POLLUTANTS INTERACTION
P50HI 14212 07 0015 Correlated ltudle^ ol pulmonary
fibrosis Pulmonary delenw mechanisms and fibiotic lung
disease (rodents, rabbits)
P50HI 15092 07 0010 Immune and fibrotic letponM to
occupational environments Chaiacteriration of toluene
diisocyanate in industrial environments
ROIHL 1602905 Bioorganic chemistry of o/one, nitrogen
dioxide and tobacco smoke
NOIHR 32903 11 Pilot study to standardize the
measurement of closing volume' (human)
PHYSICAL FITNESS
SEE HEALTH. PHYSICAL FITNESS
PHYSICAL PROPERTIES (STATES)(PROCESSES)
SEE ALSO CHEMICAL STRUCTURE
SEE ALSO CHEMISTRY. QUANTUM (GENERAL)
SEE ALSO ENVIRONMENT. ATMOSPHERIC PRESSURE
SEE ALSO ENVIRONMENT. GRAVITY MOTION
SEE ALSO ENVIRONMENT. STRESS MECHANICAL
SEE ALSO MOLECULAR FRICTIONAL PROPERTIES
SEE ALSO MOLECULAR POLARITY
SEE ALSO MOLECULAR SIZE
SEE ALSO MOLECUUR WEIGHT
SEE ALSO TEMPERATURE (SEE ALSO THERM )
ROlHL-12528 10 NMR relaxation of liquid crystal systems
ROIHL 12760-09 Surface studies of membrane lipids and
proteins
ROIHL 14111-07 Cholesteryl esters in membranes and
atherosclerosis (human, swine)
ROIHL 17543-03 0003 Magnetic tracers for diagnosis of
lung disease Occupationally accumulated magnetite for
diagnosis of lung disease (human)
ROIHL 17878-04 Structural studies of the human
erythrocyte membrane
R01HL18048-04 Dynamics of artificial and biological
membranes (human)
ROIHL 18441-03 Guidelines for polymers acting as elastin
substitutes
** POlHL-19717-02 0004 Response of the lung to injury -
Regulatory and physical-chemical properties of lung lysyl
oxidase (animals)
** R23HL-20576-01 Airway turbulence and pulmonary oxygen
exchange
ROlHL-20613-02 Mechanical properties of isolated
myocardium
ROlHL-22771-01 Thrombogenic phospholipid surfaces
(cattle)
ROlHL-23003-01 Bulk-surface distribution of cholesteryl
esters
PHYSICAL PROPERTIES, ADHESION
SEE ALSO CELL ADHESION
SEE ALSO SURGICAL ADHESIVES
ROlHL-01648-31 Blood coagulation and hemophilia (dogs.
swine)
ROlHL-14344-07 Platelet function and adenine nucleotide
metabolism (human)
ROlHL-14697-07 Role of platelet membranes in
hemostasis (human)
ROlHL-15335-06 The nature of the collagen-platelet
interaction (animals)
ROlHL-15616-04 Platelet membrane proteins In
aggregation (human)
ROlHL-19278-03 Ristocetin induced platelet aggregation
(human)
** ROlHL-22951-01 Studies on the affect of vitamin E on
platelets (human, rats)
NOlHV-52907-04 Interactions of platelets with collagens
(human, mammals)
PHYSICAL PROPERTIES, ADSORPTION
POlHL-06285-18 0208 Cardiovascular-respiratory
physiology and biochemistiy - Composition, properties and
turnover of pulmonary surfactant (human, animals)
POlHL-15195-04 0002 Program project in biological
materials - Structural and surface characterization
ROlHL-15668-06 Extracorporeal respiratory gas exchange-
A new approach (dogs)
POlHL-16851-04 0008 Human red cell membrane in
health and disease Force balance in red cell interactions
(human)
ROlHL-19700-03 Deposition of hygroscopic aerosols
(models)
ROlHL-19715-02 Respiratory tract deposition of
hygroscopic aerosols (dogs, human)
POlHL-22163-01 0001 Surface thrombogenesis-
Mechanisms and prevention - Initial blood protein and
platelet interactions with biomaterials (baboons)
NOlHV-32917-08 Materials development and testing
PHYSICAL PROPERTIES, AEROSOLS
SEE ALSO PHYSICAL PROPERTIES. FLUID STATE. VAPORS
SEE ALSO PHYSICAL PROPERTIES. PARTICLES. DUST
ROlHL-10834-09 Fetal and neonatal pulmonary circulation
(goats)
ROlHL-16463-05 Localization of airways obstruction and
responses
(contd)
•Excludes routine methodology OR covers only general proierts which preclude indexing at the specific level.
**0nented significanthf to above subject.
M Grant has subprojeds describing specific research aspects.
See Appendix for investigator's name and grant number.
PHY
ROlHL-17543-03 0001 Magnetic tracers for diagnosis of
lung disease ■ Chronic, interstitial lung disease (human,
rabbits)
ROlHL-18028-03 Absorption of nonvolatile compounds
from the lung
P50HL-19170-02 0004 Harvard pulmonary SCOR-Chronic
diseases of the airways ■ Exercise, increased ventilation
effect on airway exposure and responses (rodent)
R01HL19431-03 Regional mucociliary transport in the
human lung
ROlHL-19647-03
ROlHL-19700-03
(models)
ROlHL-19722-03
(models)
ROlHL-20105-02
Therapeutic aerosols
Deposition of hygroscopic aerosols
Aerosol growth in the respiratory system
Deposition of hygroscopic aerosols in
bronchi (dogs, human, models)
ROlHL-20622-02 Pulmonary uptake and accumulation of
drugs (rabbits, rats)
ROlHL-22415-01 Mechanisms responsible for disease
severity in asthma (human)
PHYSICAL PROPERTIES, AEROSOL AND PARTICLE
BEAMS
P50HL-14212-07 0015 Correlated studies of pulmonary
fibrosis - Pulmonary defense mechanisms and fibrotic lung
disease (rodents, rabbits)
ROlHL-20024-03 Therapeutic aerosols-Characteristics and
retention (human, dogs)
PHYSICAL PROPERTIES, COALESCENCE
SEE ALSO PHYSICAL PROPERTIES, EMULSIONS
ROlHL-1749407 Mechanism of liqand binding to
hemoglobin (human)
R01HL18819-07 Chemical studies on sickle cell
hemoglobin (human)
PHYSICAL PROPERTIES, COLLOIDS, COLLOIDAL
STATE
SEE ALSO CHEMICAL AGGREGATES, MICELLE FORMATION
SEE ALSO PHYSICAL PROPERTIES, AEROSOLS
SEE ALSO PHYSICAL PROPERTIES, EMULSIONS
SEE ALSO PHYSICAL PROPERTIES, SUSPENSIONS
** R01HL14826-05 External isotope assay of atherosclerosis
(rats, rabbits)
** ROlHL-201 76-02 Biochemistry and genetics of salt
hypertension (rats)
PHYSICAL PROPERTIES, COLLOIDS, GELS
P01HL06285-18 0215 Cardiovascular-respiratory
physiology and biochemistry - Conformation of biopolymers
POlHL-13738-08 0005 Cardiac assist devices and
artificial hearts - Development of new materials for
artificial heart and assist devices (sheep, dog)
P60HL-15157-07 0011 Comprehensive center for sickle
cell disease - Development of specific anti-sickling
compound (human)
P60HL-15168-07 0009 Comprehensive sickle cell disease
center - Spin-label study of sickling (human)
** POlHL-16833-04 0002 Hemoglobin and red cell system in
hemoglobinopathies - Polymerization and gel formation in
solutions of hemoglobin A and S (human)
** ROlHL-16921-05 Synthetic hydrogels as blood tolerable
materials
ROlHL-18818-04 Stereochemical mechanism of sickling of
hemoglobin S (human)
" POlHL-21016-02 0002 Sickle cell anemia and other
hemoglobinopathies - Molecular events proceeding gelation
of Hb S
POlHL-21016-02 0003
hemoglobinopathies
and sickling
POlHL-21016-02 0008
hemoglobinopathies
anemia
POlHL-21016-02 0009
hemoglobinopathies
Sickle cell anemia and other
Role of non-S hemoglobin in gelation
Sickle cell anemia and other
The clinical variations of sickle ceil
Sickle cell anemia and other
Nitrogen mustards and their potential
use as antisickling agent
POlHL-21016-02 0010 Sickle cell anemia and other
hemoglobinopathies - Alkylureas as potential anti-sickling
agents
ROlHL-21282-01 Dynamics of interstitial space In whole
animals (rats)
ROlHL-21498-02
R01HL-22654-0I
(human)
ROlHL-22699-01
swine)
ROlHL-23267-01
gelation (human)
N01HV-12017-15
Pathophysiology of edema (rats, cats)
Molecular structure of sickle cell fibers
Defibrillation electrode studies (dogs,
Rheology and kinetics of hemoglobin S
Fabrication of grafted hydrogel coatings
for plastic heart assist devices
PHYSICAL PROPERTIES, COLLOIDS, MAGNETIC
" P01HL13737-07 0024 Assisted circulation - Dynamic
prosthetic myocardium (dogs)
PHYSICAL PROPERTIES, CRYSTALS,
CRYSTALLIZATION
SEE ALSO CHEMICAL AGGREGATES, MICELLE FORMATION
ROlHL-13989-05 Role of water in respiratiory protein
structure
ROlHL-16601-05 Structure and function of blood proteins
(human, cattle)
416
ROlHL-18533-03 Microcrystalline and crystalline fibrinogen
(cattle, bacteria)
R01HL-186I2-03 Thin filament control of heart contraction
(cattle)
PHYSICAL PROPERTIES, CRYSTALS, LIQUID
** ROlHL-12528-10 NMR relaxation of liquid crystal systems
ROlHL-18623-12 Physical chemistry of biologically active
lipids (bacteria, plant, cattle, human)
PHYSICAL PROPERTIES, DENSITY (SPECIFIC
GRAVITY)
POlHL-07896-15 0014 Environmental biomedical research
program - Mechanisms of respiration and circulation
(human, dogs)
PHYSICAL PROPERTIES, DENSITY, AAAGNETIC
SUSPENSION METHODS*
NOlHV-42961-06 Evaluation of biomaterials in contact
with blood (dogs)
PHYSICAL PROPERTIES, DENSITOMETRY*
SEE ALSO CARDIOVASCULAR VISUALIZATION, ROENTGEN
VIDEODENSITOMETRY*
ROlHL-19003-03 High precision densitometry of coronary
angiograms
PHYSICAL PROPERTIES, DIFFUSION
SEE ALSO BIOLOGICAL TRANSPORT, MEMBRANE
PERMEABILITY AND TRANSPORT
SEE ALSO BIOLOGICAL TRANSPORT, PASSIVE TRANSPORT
DIFFUSION
SEE ALSO IMMUNOLOGICAL TESTS AND IMMUNOASSAY,
IMMUNODIFFUSION TESTS*
M POlHL-08899-14 Tolerance to respiratory gases in health
and disease
** POlHL-0889914 0029 Tolerance to respiratory gases in
health and disease • Isobaric gas counter diffusion
phenomena (human, pigs)
** POlHL-08899-14 0072 Tolerance to respiratory gases in
health and disease - Inert gas exchange isobaric gas
counterdiffusion and decompression
POlHL-08899-14 0073 Tolerance to respiratory gases in
health and disease - Biophysical mechanisms involved in
isobaric gas counterdiffusion syndrome
** POlHL-08899-14 0074 Tolerance to respiratory gases in
health and disease - Biomathematical analysis of isobaric
gas exchange and bubble formation
** POlHL-08899-14 0075 Tolerance to respiratory gases in
health and disease ■ Gas diffusion rates and bubble
formation across membranes (animals)
** POlHL-08899-14 0076 Tolerance to respiratory gases in
health and disease ■ Bubble formation during gas
counterdiffusion (hamsters)
** POlHL-08899-14 0077 Tolerance to respiratory gases in
health and disease - Isobaric gas supersaturation patterns
** POlHL-08899-14 0078 Tolerance to respiratory gases in
health and disease - Isobaric gas counterdiffusion -Sensory,
cutaneous and systemic function (animals)
** POlHL-08899-14 0079 Tolerance to respiratory gases in
health and disease - Physiological factors in
counterdiffusion bubble formation (human, pigs)
** POlHL-08899-14 0080 Tolerance to respiratory gases in
health and disease - Dynamic quantitation of continuous
isobaric gas embolization
POlHL-08899-14 0085 Tolerance to respiratory gases in
health and disease - Search for gas bubbles in vestibular
fluids (animals)
ROlHL-09739-13 Biophysical studies of proteins (human)
ROlHL-12528-10 NMR relaxation of liquid crystal systems
** POlHL-144 14-07 0004 Environmental influences on
cardiorespiratory and cellular functions - Role of diffusion
in gas exchange (chicken egg)
** POlHL-144 14-07 0016 Environmental influences on
cardiorespiratory and cellular functions - Effects of
pressure on membrane and cellular function (human,
rabbits)
POlHL-15194-07 0009 Pathophysiology of
cardiopulmonary dysfunction - Kinetics of gas exchange-
Diffusion and erythrocytes reaction rates (human, dogs)
POlHL-151 95-04 0002 Program project in biological
materials - Structural and surface characterization
ROlHL-18022-03 Role of multicomponent diffusion in gas
exchange (avian eggs)
ROlHL-19139-03 Dispersion of diffusible indicators in the
body (human, cats, dogs)
** ROlHL-22406-01 Isobaric vascular bubbles and
decompression sickness (goats, models)
PHYSICAL PROPERTIES, ELASTICITY
SEE ALSO PHYSICAL PROPERTIES, VISCOSITY-
VISCOELASTICITY
SEE ALSO PLASTICS, ELASTOMERS
** POlHL-08682-15 0005 Regulation of the cardiovascular
system - Smooth muscle and mechanical properties of
blood vessels (dogs, human)
POlHL-10342-13 0006 The integrated function of
respiration and circulation - Lung inflation effects on
pulmonary vasculature and interstitial space (dogs)
ROlHL-1 11 52-12 Vascular physiology (human, cats, dogs)
** P01HL-11310-12 0094 Mechanisms of cardiovascular
disease - Physics of pulsatile fluid flow (dogs)
** POlHL-11310-12 0101 Mechanisms of cardiovascular
disease - Molecular pathogenesis of vascular disease
PHY
** P01HL-I3737-07 0035 Assisted circulation ■ Mapping the
geometry and elasticity of the aorta
** POlHL-14388-07 0166 Regulation of the circulation in
pathological states - Elastic changes in abdominal aorta
with atherosclerosis (Rhesus monkeys)
ROlHL-14495-05 Solid and structural mechanics of lungs
(mammals)
POlHL-14580-07 0002 Program project in respiratory
mechanics - Airway aerodynamics (human, dogs)
POlHL-1583206 0005 Chemical-structural predispositions
to lung injury - Pulmonary structure and stress-strain
relationships (rats)
POIHL- 15835-06 0012 Study of muscles related to heart
disease - Contraction and energetics of visceral and
vascular smooth muscles (rabbits)
ROlHL-16711-05 RBC and endothelial membrane material
characteristics (human)
** P50HL-17669-04 0007 Ischemic heart disease center
(SCOR) - Relationship between myocardial depression and
compliance (dogs, cats)
POlHL-17731-04 0001 Physiological basis of pulmonary
disease - Mechanisms of blood flow and ventilation (dogs)
POlHL-17731-04 0002 Physiological basis of pulmonary
disease - Biomechanics of the lung (frogs, cats)
ROlHL-18676-03 Myocardial sarcomere mechanics (rat)
ROlHL-18931-02 Lung elastic tissue characteristics
(swine, human)
** ROlHL-19133-03 Contractile and elastic properties of
cardiac muscle (cats)
** ROlHL-20241-02 Shear and area moduli for abnormal red
cell membranes (human)
R23HL-21539-02 Mechanical properties of isolated small
bronchioles (rabbits)
POlHL-2 1584-02 0001 Respiratory mechanics in normal
and abnormal states - Engineering analysis of lung
deformation (human, animals)
ROlHL-22313-01 Lung elastic recoil-Age and disease
(human)
R23HL-22745-01 Vascular mechanics and structure in
hypertension (miniature swine)
R23HL-22975-01 Dynamics of autoregulation of muscle
blood flow (dogs)
NOlHR-62910-02 Fibroprotein networks of pulmonary
alveolar wall (human)
PHYSICAL PROPERTIES, EMULSIONS
SEE ALSO PHYSICAL PROPERTIES, COALESCENCE
SEE ALSO PHYSICAL PROPERTIES, SUSPENSIONS
P01HL04664-18 0001 Cardiovascular and lung dynamics
- X-ray projection image videodensitometry (dogs)
ROlHL-15520-06 Total blood replacement by fluorocarbons
and polyols (rats)
ROlHL-16855-03 Cavitation in biological systems
(microorganisms, animals)
POlHL-22633-01 0004 Cellular and molecular biology of
lipoprotein metabolism - Lipid-lipid and lipid-protein
interactions in serum lipoproteins (human, rats)
PHYSICAL PROPERTIES, FLOWMETERS, STOP
FLOW TECHNIQUE*
** ROlHL-12879-09 0008 Pulmonary transport and
metabolism in vivo - Stop-flow technique for permeability
measurements
ROlHL-16660-06 Phospholipid-cholesterol and
phospholipid-protein interactions
PHYSICAL PROPERTIES, FLUID DYNAMICS
(GENERAL)
SEE ALSO CARDIOVASCULAR FUNCTION. BLOOD CIRCUUTION
DYNAMICS (GENERAL)
POlHL-06285-18 0155 Cardiovascular-respiratory
physiology and biochemistry - Therapeutic alterations.
contractile state in heart failure
POlHL-06285-18 0157 Cardiovascular-respiratory
physiology and biochemistry - Left ventricle outflow
impedance analysis (human)
ROlHL-1 171 7-09 Effect of stenotic obstructions on flow in
arteries (dogs)
ROlHL-12493-10 Bioengineering analysis of microvascular
function (cats, rabbits)
ROlHL-12607-10 Dynamics of pulsatile blood flow (human.
dogs, rats)
ROlHL-15270-06 Local mechanical properties of the aortic
tissue (dogs, pigs)
** POlHL-17421-05 0001 Regulation and exchange in the
microcirculation - Mass transfer and microcirculatoiy
function (rats)
ROlHL-17859-04
dynamics
ROlHL-18426-04
ROlHL-19139-03
Computational methods in cardiac fluid
Regulation of renal hemodynamics (dogs)
Dispersion of diffusible indicators in the
body (human, cats, dogs)
ROlHL-19454-02 Rheological factors in transport across
arterial wall (dogs)
ROlHL-20105-02 Deposition of hygroscopic aerosols in
bronchi (dogs, human, models)
ROlHL-20773-02 Surfactant, pulmonary edema, and lung
mechanics (rabbits)
NOlHV-72939-01 Develop and evaluate left heart assist
blood pumps (human, calves, pigs)
PHYSICAL PROPERTIES, FLUID FLOW
SEE ALSO BLOOD AND RE SYSTEM, LYMPH FLOW
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level
••Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
PHY
SEE Also CARDIOVASClllAR fUNCIION. BIOOO flOW
ROIHL 12083 U Flow lield in aorta and its ma|oi
brinchts (dots, phantom models)
ROIHI 12528 10 NMR relaxation ol liquid crystal systams
ROIHL 14844 06 Mucous jlycopiotein in tiuman lespiiatory
epithelium (also wheat)
M POIHL 15194 0/ Pathophysiology ol cardiopulmonary
dysfunction
ROIHI 1757604 Role o( sphingomyelin in biomembranes
and bilayers (rats, other mammals)
ROIHL 18004 02 Transport through arterial wall-
Biophysical aspects (rabbits)
ROIHL 18255 04 Lipid protein interactions and calcium
transport (models)
POIHL 1857603 0010 Thrombosis research program
proiect Evaluation of non thrombogenic materials (cattle)
•* ROlHL-22223 01 The cardio pulmonary junction (dogs,
models)
ROIHL 22463 02 Pinocytotic vesicles and pulmonary
edema (rats)
N01HV1201715 Fabrication of grafted hydrogel coatings
tor plastic heart assist devices
PHYSICAL PROPERTIES, HUID FLOW IMPEDANCE
SEE ALSO CARDIOVASCULAR FUNCTION. BLOOD FLOW
llylPEDANCE
ROIHL 1903802 Plethysmographic evaluation of carotid
blood flow (human, rabbits, dogs)
PHYSICAL PROPERTIES, FLUID STATE
SEE ALSO BODY FLUIDS (AND RELATED SUBSTANCES)
SEE ALSO GASES (GENERAL)
SEE ALSO PHYSICAL PROPERTIES. EMULSIONS
P01HL1373707 0024 Assisted circulation Dynamic
prosthetic myocardium (dogs)
R01HL1862312 Physical chemistry of biologically active
lipids (bacteria, plant, cattle, human)
ROlHL-2088202 Interactions of plasma lipoproteins with
erythrocytes (Rhesus, human)
PHYSICAL PROPERTIES, FLUID STATE,
HYDROSTATIC PRESSURE
ROlHL-00759-29 Regulation of electrolyte and acid base
equilibrium (dogs)
P01HL0628518 0199 Cardiovascular-respiratory
physiology and biochemistry ■ Renal tubular reabsorption of
sodium chloride (hamsters, rabbits)
POlHL-06664-17 0037 Cardiopulmonary function in
remediable vascular disease Salt and water balance of
cells and tissues (rabbits)
M POlHL-07896-15 Environmental biomedical research
program
P01HL07896-15 0008 Environmental biomedical research
program ■ Otologic studies under hyperbaric conditions
(human, animals)
** POlHL-07896-15 0014 Environmental biomedical research
program - Mechanisms of respiration and circulation
(human, dogs)
POlHL-07896-15 0029 Environmental biomedical research
program • Oxygen-helium diving resulting in high pressure
nervous syndrome (human, animals)
POlHL-07896-15 0051 Environmental biomedical research
program - Relationships of retinal circulation to disease
(rabbits)
POlHL-07896-15 0062 Environmental biomedical research
program ■ Vectorcardiograms during diving (human, dogs)
M POlHL-08899-14 Tolerance to respiratory gases in health
and disease
** POlHL-08899-14 0022 Tolerance to respiratory gases in
health and disease ■ Effect of inert gas and hydrostatic
pressures on physiological functions (monkey)
ROlHL-09562-14 Cardiac protein synthesis, overload,
alcohol and anoxia (guinea pigs)
** POlHL-11678-11 0057 Cardiovascular dynamics and their
control - Return of urine to circulation using cystico-caval
shunt (dogs)
** POlHL-1 1678-11 0070 Cardiovascular dynamics and their
control - Interaction of the four Starling forces (dogs)
ROlHL-1 1906-11 Comparative study of heart function
(cats. rats, hedgehogs, squirrels)
POlHL-12157-11 0060 Functions and mechanisms of cell
membrane ion transport - Ion transport and electrical
properties of giant-celled aiga
M R01HL12879-09 Pulmonary transport and metabolism in
vivo
ROlHL-13323-08 Intrarenal pressure and renal function
(human, dogs)
ROlHL-13437-09 Physical and mechanical parameters in
the microcirculation (animals)
P50HL-142 18-07 0017 Pulmonary SCOR -Newborn lung
center - Transvascular fluid exchange, vasoactive mediators
in ROS (sheep, cat)
•* POlHL-14414-07 0010 Environmental influences on
cardiorespiratory and cellular functions - Pressure effects
on cardiac electrical phenomena (animals)
POlHL-14414-07 0014 Environmental influences on
cardiorespiratory and cellular functions - Temperature and
acid-base status in tissues, cells, and subcellular system
** POlHL-14414-07 0016 Environmental influences on
cardiorespiratory and cellular functions - Effects of
pressure on membrane and cellular function (human,
rabbits)
417
ROIHL 15655 05 Blood flow and gas exchinge in placenta
and lungs (sheep) rabbits)
ROIHI 16254 05 Pathogenesis ol bubble and clot
foimation (fish)
POIHL 1/421 05 0001 Regulation and exchange in the
microcirculation Mass transfer and microcifculatory
function (rats)
POIHI 17421 05 0002 Regulation and exchange in the
microcirculation Metabolic and myogenic blood flow
regulation in microcirculation (animals)
POIHL 17421 05 0003 Regulation and exchange in the
microcirculation Transcapillary fluid exchange in rat
intestinal muscle, mucosa, and mesentery
ROIHL 1842604 Regulation ol renal hemodynamics (dogs)
ROIHL 18606 04 Pathogenesis and measurement of
pulmonary edema (human, rabbits, dogs)
ROIHL 18875 03 Angiotension. prostaglandins, pressure
and the kidney (rats)
ROIHL 19366 03 Renal Starling forces in experimental
conditions (rats, rabbits)
ROIHL 19677 03 Venous structure and function (dogs)
ROlHL-20652 01 Sites of leakage in pulmonary edema
(dogs)
ROIHL 20690 02 Pulmonary hemodynamics in lung edema
during PEEP (dogs)
R23HL 21050-02 Mechanisms of reexpansion pulmonary
edema (rabbits)
R23HL21382-02 Effect of pressure on renal blood flow
and function (dogs)
ROIHL 21498-02 Pathophysiology of edema (rats, cats)
ROlHL-22223 01 The cardiopulmonary junction (dogs.
models)
ROlHL-22406-01 Isobaric vascular bubbles and
decompression sickness (goats, models)
ROlHL-22549-02 Transport across alveolar capillary
membrane (dogs)
ROlHL-22924-01 The airway mucosal barrier (guinea pigs)
ROlHL-230 15-01 Mechanisms of hypo-oncotic pulmonary
edema (human, dogs)
PHYSICAL PROPERTIES, FLUID STATE, OSMOTIC
PRESSURE
SEE ALSO BLOOD OSMOTIC PRESSURE
SEE ALSO BODY FLUID BAUNCE. OSMOTIC PRESSURE
SEE ALSO CELL FLUIDS. OSMOTIC PRESSURE
ROlHL-12974 10 Tracer kinetics, flows and masses in
body organs (human, dogs)
POlHL-144 14-07 0014 Environmental influences on
cardiorespiratory and cellular functions - Temperature and
acid-base status in tissues, cells, and subcellular system
POlHL-19242-02 0003 Study of vascular smooth muscle -
Vasoactive metabolites from vascular muscle and
parenchymal tissue (animal)
POlHL-19737-02 0011 Cellular and molecular aspects of
respiratory physiology - Chemical and metabolic factors on
peripheral chemoreceptor activity (cats)
POlHL-2101602 0002 Sickle cell anemia and other
hemoglobinopathies - Molecular events proceeding gelation
of Hb S
ROlHL-22549-02 Transport across alveolar capillary
membrane (dogs)
POlHL-22619-01 0010 Cellular mechanisms of heart
failure - Mitochondria in heart and smooth muscle (rabbits,
rats, dogs)
PHYSICAL PROPERTIES, FLUID STATE, VAPORS
P50HL-15092-07 0005 Immune and fibrotic response to
occupational environments - Respiratory and immunologic
evaluation of toluene diisocyanate exposure (human)
P50HL-15092-07 0010 Immune and fibrotic response to
occupational environments Characterization of toluene
diisocyanate in industrial environments
ROlHL-19647-03 Therapeutic aerosols
ROlHL-22273-01 Oral and lung absorption of nitroglycerin
(rats)
PHYSICAL PROPERTIES, MECHANICAL PRESSURE
SEE ALSO PHYSICAL PROPERTIES. TENSILE STRENGTH
POlHL-04664-18 0004 Cardiovascular and lung dynamics
- X-ray cross section imaging of the circulation (dogs)
POlHL-06285-18 0153 Cardiovascular-respiratory
physiology and biochemistry - Myocardial mechanics and
pharmacology in isolated papillary muscle (animals)
** POlHL-08682-15 0005 Regulation of the cardiovascular
system - Smooth muscle and mechanical properties of
blood vessels (dogs, human)
M POlHL-10342-13 The integrated function of respiration
and circulation
POlHL-10342-13 0006 The integrated function of
respiration and circulation - Lung inflation effects on
pulmonary vasculature and interstitial space (dogs)
** POlHL-11310-12 0085 Mechanisms of cardiovascular
disease - Mechanics of isolated cardiac muscle (animals)
*' POlHL-1 13 10-12 0086 Mechanisms of cardiovascular
disease - Mechanics of the intact left ventricle (dogs)
** POlHL-11351-12 0003 Cellular and molecular
mechanisms of myocardial function - Mechanical and
electrical properties of cardiac muscle (rabbits)
POlHL-11351-12 0019 Cellular and molecular
mechanisms of myocardial function - Mechano-chemical
kinetics of small perturbations
ROlHL-12494-10 Continuum mechanics in biophysics
(human, animals)
•Excludes routine methodology OR covers only general projects which preclude
**Ohented significantly to above subject.
indexing at the specific level.
M Grant has subprojects descnbing si
See Appendix for investigator's name
PMY
ROIHI 13323 08 Intrarenal pratiuit and renal function
(human, dogs)
POIHL 13/3/ 0/ 0007 Auiilad circulation
Delerminalion ol cardiac ilatui by UM ol balloon pump
(dogs)
POIHI 13/38 08 0005 Cardiac assist davicei and
artificial hearts Development ol new matefialt loi
artificial heart and assist devices (sheep, dog)
ROIHL 13803 0/ Advanced cardiac valvular and vascular
prosthesis (dogs, baboons)
POIHI 14388 0/ 0179 Regulation ol the circulation in
pathological states Cultured muscle cells and their crOM-
innervation in vitro (rats, sheep)
* ROIHL 14523 0/ Generation and regulation of force in
smooth muscle (animals)
ROIHL 14854 0/ Lung and tissue mechanics (monkeys.
dogs)
POIHL 1519504 0001 Program project in biological
materials Design and synthesis
POIHL 15195 04 0003 Program proiect in biological
materials Mechanical evaluation and fabrication
'* ROIHL 15526 05 Respiratory mechanics in children
POIHL 15835 06 0012 Study of muscles related to heart
disease Contraction and energetics of visceral and
vascular smooth muscles (rabbits)
ROlHL-16768 04 The sympathetic nervous system and the
arterial wall (rabbits, pigeons)
POIHL 16833 04 0008 Hemoglobin and red cell system in
hemoglobinopathies Membrane associated phenomena in
SS disease
POlHL-16878-05 0001 Control of ventilation in health
and disease Ability of asthmatics to detect added
resistive and elastic loads
ROIHL 17335-06 Contractile properties of hypertensive
arterioles (rats)
ROIHL 1743703 'Perfusion lung' -Role of traumatized
leukocytes (dogs, human)
ROIHL 17865-04 Studies on aging -Effects of sex
hormones (rats, dogs)
M POIHL 18208-04 Center for the study of blood cell
rheology
POlHL-18208-04 0005 Center for the study of blood cell
rheology - RBC deformability and capillary flow
interrelations (human, mice)
** POlHL-18208-04 0006 Center for the study of blood cell
rheology - Analysis of flow in arterioles and capillaries
(human)
POlHL-18575-03 0006 Mechanisms of vascular changes
in hypertension - Evaluation of arterial compliance in
hypertension (human, pigs)
ROlHL-18738-02 Prevention of postoperative venous
thrombi (human, cattle)
** ROlHL-18749-03 Ventricular mechanics in the overloaded
heart (dogs)
ROlHL-18912-03 Mechanics of heart muscle contraction
(cats, dogs)
ROlHL-18977-03 Non-invasive diagnosis of peripheral
arterial disease (human, dogs)
ROIHL 19012-03 Smooth muscle of resistance vessels in
hypertension (rats)
R01HL19133-03 Contractile and elastic properties of
cardiac muscle (cats)
POlHL-19242-02 0006 Study of vascular smooth muscle -
The contractile system of vascular smooth muscle (swine,
rats)
ROlHL-19275-03 Characterization of collateral blood
vessels (dogs)
** ROlHL-19460-03 Mechanics of the papillary muscle and
the left ventricle (cats, rabbits)
'* ROlHL-19677-03 Venous structure and function (dogs)
** POlHL-19717-02 0009 Response of the lung to injury -
Time-dependent mechanical properties of lung connective
tissues (hamsters)
POlHL-19717-02 0010 Response of the lung to injury •
Proteoglycans in lung function and structure (hamsters)
POlHL-19717-02 0018 Response of the lung to in|ury
Lung mechanics and connective tissue composition in
human emphysema
POlHL-19717-02 0023 Response of the lung to injury -
Postnatal lung development -Cells, connective tissue and
physiology (animals)
ROlHL-20122-02 Operational mechanisms of airway
receptors (dogs, pigs)
ROlHL-20196-02 Regulation of coronary arterial smooth
muscle
ROlHL-20371-02 Intravascular redistribution of blood
volume (dogs)
** POlHL-20552-02 0003 The development and regression of
cardiac hypertrophy - Muscle mechanics of the
hypertrophied left ventricle (rats)
POlHL-20552-02 9002 The development and regression of
cardiac hypertrophy - Core B -Biomathematics
** ROlHL-20648-01 Physical factors and coronary flow (dogs)
ROlHL-20749-01 Developing heart-Biophysical aspects
(sheep)
** ROlHL-21 103-01 Parametric mechanical studies of
hypertensive arteries (dogs, rats)
R23HL-21234-02 The regulation of cardiac hypertrophy
(rabbits)
ROlHL-21312-01 Sarcomere mechanics in disrupted
ventricular muscle (guinea pigs)
(contd)
ipecific research aspects,
and grant number.
PHY
R23HL-21325-02 Sarcomere kinematics in cardiac
contraction (ratso rabbits)
ROlHL-21425-02 Servo-simulated compliance changes-A
reversible Ml (dogs)
R23HL-2 1462-02 Mechanical interactions between ventricle
arteries (dogs)
R23HL-21539-02 Mechanical properties of isolated small
bronchioles (rabbits)
M POlHL-2 1584-02 Respiratory mechanics in normal and
abnormal stales
POlHL-21584-02 0001 Respiratory mechanics in normal
and abnormal states - Engineering analysis of lung
deformation (human, animals)
" POlHL-21584-02 0002 Respiratory mechanics in normal
and abnormal states - Lung mechanics-Regional
deformation and ventilation (dogs)
POlHL-21584-02 0003 Respiratory mechanics in normal
and abnormal states - Effects of anesthesia on ventilation
and respiratory mechanics in man
POlHL-21584-02 0006 Respiratory mechanics in normal
and abnormal states - Respiratory mechanics in health and
disease (human, pigs)
ROlHL-21850-01 Calcium transport in the hypertrophied
myocardium (rats, animals)
** ROlHL-21993-01 Hypertensive hypertrophy-Effects of
cardiac mechanics (rats)
ROlHL-22269-01 Excitation-contraction coupling in
enlarged hearts (rabbits)
ROlHL-22313-01 Lung elastic recoil -Age and disease
(human)
ROlHL-22667-01 Mechanisms of baroreceptor adaptation
in hypertension (dogs)
R23HL-22745-01 Vascular mechanics and structure in
hypertension (miniature swine)
NOlHV-32950-08 Blood compatible poly-electrolytes
NOlHV-72919-01 Test polymers for circulatory assist
divices
PHYSICAL PROPERTIES, PARTICLES
P50HL-14153-07 0016 Johns Hopkms Lung Center-
Chronic diseases of airways - Airways defense mechanisms
(dogs)
P50HL-14212-O7 0004 Correlated studies of pulmonary
fibrosis - Collagen metabolism in lung tissue and lung
cells (human, animal)
P50HL-14212-07 0006 Correlated studies of pulmonary
fibrosis - Alveolar macrophage physiology (human, rodents,
rabbits)
P50HL-14212-07 0007 Correlated studies of pulmonary
fibrosis - Protein metabolism in alveolar macrophages
(rabbits, guinea pigs, human)
** P50HL-14212-07 0012 Correlated studies of pulmonary
fibrosis - Inorganic particulates in tobacco, smoke and
lungs of cigarette smokers (human)
P50HL14212-07 0015 Correlated studies of pulmonary
fibrosis - Pulmonary defense mechanisms and tibrotic lung
disease (rodents, rabbits)
ROlHL-19431-03 Regional mucociliary transport in the
Therapeutic aerosols
Deposition of hygroscopic aerosols
human lung
ROlHL-19647-03
ROlHL-19700-03
(models)
ROlHL-19715-02 Respiratory tract deposition of
hygroscopic aerosols (dogs, human)
** RC1HL19722-03 Aerosol growth in the respiratory system
(models)
ROlHL-20105-02 Deposition of hygroscopic aerosols in
bronchi (dogs, human, models)
PHYSICAL PROPERTIES, PARTICLES, DUST
SEE ALSO HYPERSENSITIVITY, ALLERGENS AIRBORNE
ROlHL-12650-08 Environmental pathobiology of the lung
(hamsters, rats)
P50HL-1509207 0001 Immune and fibrotic response to
occupational environments - X-ray diffraction study-Dust
exposure in asbestos cement products manufacturing
P50HI-1 5092-07 0002 Immune and fibrotic response to
occupational environments • Longitudinal study of
sandblasters silicosis (human)
P50HL- 15092-07 0006 Immune and fibrotic response to
occupational environments - Immunologic studies in
silicosis (human, rabbits, hamsters, guinea pigs)
P50HL-1 5092-07 0007 Immune and fibrotic response to
occupational environments - Asbestosis-Cellular immunity,
structure and mineral localization (human)
P50HL-15092-07 0008 Immune and fibrotic response to
occupational environments - Animal models of asbestosis
(hamsters)
P50HL-1 5092-07 0011 Immune and fibrotic response to
occupational environments - Respiratory and immunologic
responses in coffee plant workers
P50HL-1 5092-07 0012 Immune and fibrotic response to
occupational environments - Longitudinal evaluation of
workers exposed to cotton dust
P50HL-1 5389-07 0008 Pulmonary SCOR-Hypersensitivity
pneumonitis - Milwaukee patient study -Hypersensitivity
pneumonitis
P50HL15389-07 0013 Pulmonary SCOR-Hypcrsensitivity
pneumonitis - Animal model-Pulmonary mycotoxicosis
(rabbit, guinea pig)
P50HL-15389-07 0014 Pulmonary SCOR-Hypersensitivity
pneumonitis - Fractionation and characterization of pigeon
antigens
418
P60HL-17292-04 0005 Vermont Lung Center - Mineral
pneumoconioses-Pathogenesis and pathology (human)
ROlHL-17543-03 0003 Magnetic tracers for diagnosis of
lung disease - Occupationally accumulated magnetite for
diagnosis of lung disease (human)
PHYSICAL PROPERTIES, PRECIPITATION
** ROlHL-21791-01 Precipitation of proteins with poly
(ethylene glycol) (human)
PHYSICAL PROPERTIES, RHEOLOGY (NOT INCl.
BLOOD)
SEE ALSO BIOLOGICAL TRANSPORT, FLUID EXCHANGE AND
TRANSPORT
SEE ALSO BLOOD AND RE SYSTEM, LYMPH FLOW/
SEE ALSO BLOOD RHEOLOGY
SEE ALSO BODY FLUIDS, VISCOSITY-VISCOEUSTICITY
SEE ALSO CELL FLUIDS, OSMOTIC PRESSURE
SEE ALSO GASTROINTESTINAL FUNCTION, DEGLUTITION
SEE ALSO NERVOUS SYSTEM, NEURONS, AXOPLASMIC FLOW
SEE ALSO NERVOUS SYSTEM CENTRAL, CEREBROSPINAL
FLUID FLOW
SEE ALSO NERVOUS SYSTEM CENTRAL, CEREBROSPINAL
FLUID PRESSURE
SEE ALSO ORAL-PHARYNGEAL, SALIVATION
SEE ALSO PHYSICAL PROPERTIES. CRYSTALS, LIQUID
SEE ALSO PHYSICAL PROPERTIES, FLUID DYNAMICS
(GENERAL)
SEE ALSO PHYSICAL PROPERTIES, FLUID FLOW
SEE ALSO PHYSICAL PROPERTIES, FLUID FLOW IMPEDANCE
SEE ALSO PHYSICAL PROPERTIES, FLUID STATE
SEE ALSO PHYSICAL PROPERTIES, VISCOSITY-
VISCOELASTICITY
SEE ALSO RESPIRATORY DISORDERS, RESPIRATORY AIRFLOW
DISORDERS
SEE ALSO RESPIRATORY DISORDERS DIAGNOSIS,
RESPIRATORY AIRFLOW MEASUREMENTS*
SEE ALSO RESPIRATORY FUNCTION. RESPIRATORY AIRWAY
PRESSURES
SEE ALSO RESPIRATORY GAS TRANSPORT
ROlHL-13885-08 0009 Cystic fibrosis and pulmonary
disease - Respiratory mucus glycoproteins (human, rabbits)
** ROlHL-19454-02 Rheological factors in transport across
arterial wall (dogs)
** ROlHL-22223-01
models)
ROlHL-22233-01
elastic property
ROlHL-22444-01
culture (human)
The cardiopulmonary junction (dogs.
Characterization of bio-materials by
Bronchial mucus production in organ
PHYSICAL PROPERTIES, SOLID STATE
SEE ALSO PHYSICAL PROPERTIES, CRYSTALS,
CRYSTALLIZATION
SEE ALSO TEMPERATURE, FREEZING
ROlHL-13652-08 Metal sites in metalloproteins
(mushroom)
ROlHL-18623-12 Physical chemistry of biologically active
lipids (bacteria, plant, cattle, human)
PHYSICAL PROPERTIES, SOLUBILITY
POlHL-07896-15 0045 Environmental biomedical research
program - Extravascular lung water dynamics in pulmonary
oxygen toxicity (human, baboons)
ROlHL-15293-07 Sickle cell hemoglobin-Interactions and
aggregation (human)
R01HL18918-03 Characterization of lung elastins (rat,
rabbit, chicken. Rhesus)
RGlHL-19065-02 Molecular oxygen in biological fluids
ROlHL-21791-01 Precipitation of proteins with poly
(ethylene glycol) (human)
ROlHL-22035-01 Molecular modification of heparin by
chemical means (sheep)
PHYSICAL PROPERTIES, SOLUBIUTY, LIPID
ROlHL-16101-05 Protein-lipid interaction (bacteria,
models)
PHYSICAL PROPERTIES, SOLUBILITY, WATER
SEE ALSO PHYSICAL PROPERTIES. SOLUTIONS, AQUEOUS
ROlHL-16921-05 Synthetic hydrogels as blood tolerable
materials
ROlHL-23120-01 Chelating agents as blood substitutes
PHYSICAL PROPERTIES, SOLUTES
** ROlHL-08977-14 Quantitation of flow and solute flux in
microvessels (cats, rats)
** ROlHL-11153-12 Quantitation of flow and solute flux in
microvessels (cats, rats)
" ROlHL-12879-09 0002 Pulmonary transport and
metabolism in vivo - Osmotic compartmental model of
barrier exchange
ROlHL-12879-09 0007
metabolism in vivo
pulmonary transport
ROlHL-17998-04 Regulatory mechanisms in blood
circulation (dogs)
ROlHL-18004-02 Transport through arterial wall-
Biophysical aspects (rabbits)
ROIHL-18736-03 Protein transport through arterial tissue
(rabbits)
ROlHL-19139-03 Dispersion of diffusible indicators in the
body (human, cats, dogs)
Pulmonary transport and
• Effects of temperature changes on
PHY
ROlHL-21376-02 Blood-gas barrier solute and water
transport (rabbits)
ROlHL-22569-02 Intestinal secretion -Capillary and tissue
forces (dogs, cats)
PHYSICAL PROPERTIES, SOLUTIONS
SEE ALSO IONS, ELECTROLYTES
SEE ALSO SALINE SOLUTIONS
POlHL-06314-17 0050 Immunologic mechanisms in
cardiovascular disease - Physiologic changes in
lymphocytes (human, mice)
P50HL-14147-08 0015 Specialized center of research in
thrombosis - Charge related properties of phospholipid
surfaces in monolayers and vesicles
P01HL1668304 0002 Function and growth of cardiac
and skeletal muscle - Myosin, actin, ATP. interaction in
solution
ROlHL-22570-01 Interactions of sterols in biological
systems (human)
PHYSICAL PROPERTIES, SOLUTIONS, AQUEOUS
SEE ALSO PHYSICAL PROPERTIES, SOLUBILITY. WATER
ROlHL-151 55-05 Rheology of pulmonary secretions (dogs)
ROlHL-16029-05 Bio-organic chemistry of ozone, nitrogen
dioxide and tobacco smoke
ROlHL-18623 12 Physical chemistry of biologically active
lipids (bacteria, plant, cattle, human)
R01HL21791-01 Precipitation of proteins with poly
(ethylene glycol) (human)
PHYSICAL PROPERTIES, SOLUTIONS
ASSOCIATION
SEE ALSO CHEMICAL AGGREGATES, MICELLE FORMATION
** POIHL 16833-04 0002 Hemoglobin and red cell system in
hemoglobinopathies - Polymerization and gel formation in
solutions of hemoglobin A and S (human)
ROlHL-18636-02 Fatty acids and cholesterol transport
(rats)
PHYSICAL PROPERTIES, SOLVENTS
P50HL-1 5092-07 0005 Immune and fibrotic response to
occupational environments - Respiratory and immunologic
evaluation of toluene diisocyanate exposure (human)
P50HL 15092-07 0010 Immune and fibrotic response to
occupational environments - Characterization of toluene
diisocyanate in industrial environments
POlHL-15195-04 0001 Program project in biological
materials - Design and synthesis
POlHL-15195-04 0003 Program project in biological
materials - Mechanical evaluation and fabrication
ROlHL-23392-01 Membrane binding and transport of
calcium and potassium ionophores
PHYSICAL PROPERTIES, SOUND
SEE ALSO HEART FUNCTION, HEART SOUNDS
♦* POlHL-19717-02 0020 Response of the lung to injury -
Recording of lung sounds in animal models of disease
(animals)
** R23HL 21199-02 Sound transmission in lung (dog)
PHYSICAL PROPERTIES, SOUND, NOISE
POLLUTION
** NOlHV-72925-04 Non-invasive detection of atherosclerotic
lesions (human, monkeys, dogs)
PHYSICAL PROPERTIES, SOUND, ULTRASONIC
SCANNING*
** P50HL14218-07 0014 Pulmonary SCOR-Newborn lung
center - Longitudinal study of ROS -Monitoring fetal
breathing movements (human)
POIHL- 14388-07 0185 Regulation of the circulation in
pathological states - Reflex control of venous tone (human,
rabbits, dogs)
ROlHL-16830-05 Non-invasive determination of aortic
blood velocities (human)
** ROlHL-17769-03 New methods of studying blood
coagulation kinetics
** ROlHL-19341-03 Ultrasonic detection of the atherosclerotic
plaque
ROlHL-19537-03 Detection of myocardial injury with
ultrasound (dogs)
** POlHL-19717-02 0045 Response of the lung to injury -
Ultrasound studies (human, hamsters)
R23HL-21253-01
image analysis
ROlHL-22506-01
Anatomical models in computer-aided
Hemodynamics of the clinical
hypertensions
** NOlHV-72924-04 Non-invasive detection of atherosclerotic
lesions (human, animals)
** NOlHV-72926-04 Ultrasonic imaging development
** NOlHV-72927-00 Systems for non-invasive detection of
atherosclerotic lesions (human)
** NOlHV-72928-04 Develop high resolution ultrasonic
imaging techniques
** NOlHV-72929-01 Improved detection of atherosclerosis
(human, dogs)
** N01HV-72932-00 Non-invasive detection of atherosclerotic
lesions (human, phantoms)
PHYSICAL PROPERTIES, SOUND, ULTRASONICS
ROlHL-20024-03 Therapeutic aerosols-Characteristics and
retention (human, dogs)
ROlHL-20869-01
ROlHL-20979-02
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Onented significantly to above subject.
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
Microvascular responses to ultrasound
A novel pulsed Doppler flowmeter (dogs)
(contd)
PHY
PHYSICAL PROPERTIES, SOUND,
ULTRASONOGRAPHY
SEE ALSO BRAIN VISUAll/AIION. UlIRASONIC
ICHOfNCEPHAlOGRAPHV
SEE ALSO CARDIOVASClllAR DISORDERS DIAGNOSIS. BIOOD
Flow MlASURfMfNIS. UlIRASONIC*
SEE ALSO HEARI VISUAIIMIION,
ANGIOCARDIOUURASONGGRAPHV
SEE ALSO HEART VISUALIMIION. ECHOCARDIOGRAPHY*
SEE ALSOOPIICS. MICROSCOPY. ULIRASONIC*
SEE ALSO OPIICS, PHOIOGRAPHY. HOLOGRAPHY. ACOUSTIC*
SEE ALSO PHYSICAL PROPERIIES. SOUND. ULTRASONIC
SCANNING*
•• P01HL04664 18 0007 Cardiovascular and lung dynamics
■ Development and application ot ultrasound imaging
techniques
** ROIHL 1478S0/ Ultrasonic scattering lor tissue
characterization (dogs, cattle, human)
ROIHL 1675905 Ultrasonic measurement ol cardiac
geometry and (low
RCIHL 2086901 Microvascular responses to ultrasound
ROIHL 22854 01 Non invasive blood pressure
measurement (rats)
PHYSICAL PROPERTIES, SOUND, ULTRASOUND
ADVERSE EFFECTS
•' ROIHL 1953703 Detection ot myocardial in|ury with
ultrasound (dogs)
ROlHL-2086901 Microvascular responses to ultrasound
PHYSICAL PROPERTIES, SOUND FREQUENCY
POIHL 1971702 0044 Response of the lung to injury -
Lung sound analysis (human)
R23HL-2 119902 Sound transmission in lung (dog)
PHYSICAL PROPERTIES, SURFACE PROPERTIES
(GENERAL)
SEE ALSO MEMBRANE SURFACE (BIOLOGICAL) ACTIVITY
(GENERAL)
P01HL06285-18 0208 Cardiovascular-respiratory
physiology and biochemistry - Composition, properties and
turnover ol pulmonary surtactant (human, animals)
P01HL06285 18 0213 Cardiovascular-respiratory
physiology and biochemistry - Membrane structure and
function -Gas vacuole membrane (Halobacterium)
** P01HL06312-17 0043 Surgical cardiology - The
cylindrical ventricular assist device (dogs)
P01HL06664-17 0042 Cardiopulmonary function in
remediable vascular disease ■ Physiologic studies on vein
grafts (dogs)
RC1HL12839-09 Flow, transport and membrane
phenomena in blood (human)
** PO1HL1373808 0005 Cardiac assist devices and
artificial hearts - Development of new materials for
artificial heart and assist devices (sheep, dog)
P50HL1414708 0003 Specialized center of research in
thrombosis - Surface thrombogenicity and phospholipid
vesicle physical properties
P50HL1414708 0013 Specialized center of research in
thrombosis - Mathematical models of blood coagulation
kinetics
P50HL14147-08 0014 Specialized center of research in
thrombosis - Theoretical models for electrostatic effects in
blood clot formation
** P50HL14147-08 0015 Specialized center of research in
thrombosis ■ Charge related properties of phospholipid
surfaces in monolayers and vesicles
** P50HL-1505207 0007 Study of lipoproteins, artery wall,
and atherosclerosis ■ Physical chemistry of lipidprotein
interaction (human)
P50HL- 15062-07 0008 Study of lipoproteins, artery wall,
and atherosclerosis - Lipid modifying enzymes (human,
monkey)
M P01HL15195-04 Program project in biological materials
** POlHL-15195-04 0002 Program project in biological
materials - Structural and surface characterization
POlHL-15195-04 0004 Program proiect in biological
materials - Biological evaluation and surface interaction
studies (dogs)
ROlHL-1533506 The nature of the collagen-platelet
interaction (animals)
ROlHL-16855-03 Cavitation in biological systems
(microorganisms, animals)
R01HL16921-05 Synthetic hydrogels as blood tolerable
materials
ROlHL-1740204 Mechanism of contact activation of
intrinsic clotting (human)
R01HL17623-05 Initial events in thrombus formation on
surfaces (human, rats)
POlHL-17731-04 0002 Physiological basis of pulmonary
disease - Biomechanics of the lung (frogs, cats)
POlHL-18577-03 0005 Lipoproteins -Cell surface
interactions - Chemical synthesis of apolipoproteins and
apoliprotein fragments
R01HL-18935-03 Platelets, fibrinogen, soluble fibrin
interaction (human)
** ROlHL-19173-03 Analysis of blood trauma from
microporous oxygenators (human, dogs, rabbits)
ROlHL-20037-02 Lett ventricular-aortic bypass and
composite prosthesis (sheep, swine, cattle)
ROlHL-20073-02 Blood compatible materials by fluid
perfusion (human, dogs)
419
•• ROIHL 20079 02 0003 Ihromboiesijlant material Blood
surface interactions (human, cattle)
ROIHI 20313 0? Surface induced thrombosis Modification
ol albumin valiants (human, goal)
R23H1 21805 01 Tissue cell interactions with vascular
prostheses (human, rats, mice)
ROIHI 21975 01 Studies on normal and abnormal factor
IX (human, dogs, cows)
POIHL 22633 01 0004 Cellular and molecular biology of
lipoprotein metabolism Lipid lipid and lipidprotein
interactions in serum lipoproteins (human, rats)
** ROIHL 23899 01 Flow and flexing at blood/biomaterial
interfaces
NOIHV 12017 15 fabrication of grafted hydrogel coalings
lor plastic heart assist devices
** N01HV32913 11 Study electrodeless glow discharge for
modifying polymer surface
** N01HV3291708 Materials development and testing
NOIHV 42928 07 Continued development of carbon film
deposits for prosthetics
NOIHV 52907 04 Interactions ol platelets with collagens
(human, mammals)
PHYSICAL PROPERTIES, SURFACTANTS
SEE ALSO RESPIRATORY SYSTEM, PULMONARY SURFACTANT
SEE ALSO TERRENES SAPONINS
ROIHL 17719-03 Lung in|ury, substrate utilization, oxygen
toxicity (rats, rabbits, dogs)
ROIHL 18002 03 Circulatory shock, trauma and REsystem
function (rats)
ROIHL 19419-03 Cellular interactions with foreign
materials (mammals)
ROlHL-20558-02 Cardiac electrophysiology-Eftects of ions
and drugs
PHYSICAL PROPERTIES, SURFACTANTS,
DETERGENTS
P01HL06285 18 0215 Cardiovascular-respiratory
physiology and biochemistry Conformation of biopolymers
ROlHL-16037 06 Molecular properties of cardiac
adrenergic receptors
ROIHL 1733204 Use of the gut for therapy of coronary
artery disease (mammals)
PHYSICAL PROPERTIES, SUSPENSIONS
SEE ALSO PHYSICAL PROPERTIES. EMULSIONS
ROlHL-1685503 Cavitation in biological systems
(microorganisms, animals)
PHYSICAL PROPERTIES, TENSILE STRENGTH
SEE ALSO ENVIRONMENT. STRESS MECHANICAL
ROlHL-01015-27 Hypertension and left ventricular
hypertrophy (dogs)
POlHL-15195-04 0003 Program project in biological
materials • Mechanical evaluation and fabrication
ROlHL-17865-04 Studies on aging -Effects of sex
hormones (rats, dogs)
** R01HL17909-04 Drug treatment of vascular scleroprotein
defects (human, turkeys)
R01HL17969-04 Function and structure of semilunar
valves (dogs)
ROlHL-191 73-03 Analysis of blood trauma from
microporous oxygenators (human, dogs, rabbits)
ROIHL 22040-01 Regulation of lysylcrosslinking in
vascular tissue (rats, turkeys)
** ROlHL-22233-01 Characterization of bio-materials by
elastic property
NOlHV-729 18-01 Test polymers for circulatory assist
devices
NOlHV-72919-01 Test polymers for circulatory assist
divices
PHYSICAL PROPERTIES, VISCOSITY-
VISCOELASTICITY
SEE ALSO BLOOD VISCOSITYVISCOELASTICITY
SEE ALSO BODY FLUIDS. VISCOSITYVISCOELASTICITY
SEE ALSO MOLECULAR FRICTIONAL PROPERTIES
P01HL06296-18 0002 Cardiovascular and pulmonary
adaptation to stress - Respiratory muscle blood flow,
mechanics and metabolism (human, dog)
P01HL06664-17 0042 Cardiopulmonary function in
remediable vascular disease - Physiologic studies on vein
grafts (dogs)
** POlHL-08682-15 0005 Regulation of the cardiovascular
system - Smooth muscle and mechanical properties of
blood vessels (dogs, human)
P01HL11310-12 0085 Mechanisms of cardiovascular
disease - Mechanics of isolated cardiac muscle (animals)
POlHL-11351-12 0003 Cellular and molecular
mechanisms of myocardial function - Mechanical and
electrical properties of cardiac muscle (rabbits)
R01HL1249410 Continuum mechanics m biophysics
(human, animals)
R01HL-1260710 Dynamics of pulsatile blood flow (human.
dogs, rats)
R01HL-14844-06 Mucous glycoprotein in human respiratory
epithelium (also wheat)
** R01HL-14854-07 Lung and tissue mechanics (monkeys,
dogs)
P50HL-15O62-07 0007 Study of lipoproteins, artery wall,
and atherosclerosis - Physical chemistry of lipidprotein
interaction (human)
R01HL1658205 Artificial lungs (dogs)
PHY
ROIHI 1 6606' II Conlriclion in heart and olhei itrnied
muscles (Irott)
ROIHI 16657 06 Innervation ol coronary »rt«ri«\ and heart
(rats)
P60HI 17269 04 0014 National heart and blood ve«Ml
research and demonstration center Physio chemical nature
of lipid deposits in arterial wall (human)
ROIHI 17576 04 Role ol sphingomyelin in biomembranej
and bilayers (rats, other mammals)
** P50HL 17669 04 000/ Ischemic heart diseaie center
(SCOR) Relationship between myocardial depression and
compliance (dogs, cats)
P50HL 17670 04 0009 Study of ischemic heart disease
Surgical treatment of localized left ventricular dyssynergy
(human, dogs)
ROIHL 18441 03 Guidelines lor polymers acting as elaslin
substitutes
** ROIHL 1908903 Diastolic properties of the left ventricle
(human, dogs)
P50HL 19190 02 0005 Pulmonary SCOR Pathophysiology,
management of IRDS Glycoproteins in mucous secretions
(human, cattle)
ROIHL 1945402 Rheological factors in transport across
arterial wall (dogs)
POIHL 19717 02 0009 Response of the lung to injury
Time dependent mechanical properties of lung connective
tissues (hamsters)
POIHL 19737 02 0010 Cellular and molecular aspects of
respiratory physiology Effects of pulsatile flow and volume
on capillary exchanges (dogs, rats)
ROIHL 21071 02 Mechanisms of hypertension in
coarctation of the aorta (dog)
ROIHL 21103-01 Parametric mechanical studies of
hypertensive arteries (dogs, rats)
ROIHL 21993 01 Hypertensive hypertrophy- Effects of
cardiac mechanics (rats)
R23HL 2224502 Functional characteristics of atrial
receptors (rats)
ROlHL-23205-01 Contraction of pulmonary vascular
smooth muscle (cat)
PHYSICAL SEPARATION, CENTRIFUGATION*
SEE ALSO PHYSICAL SEPARATION. ULTRACENTRIFUGATION*
ROIHL 2078802 Preservation of human platelets for
transfusion
PHYSICAL SEPARATION, CHROMATOGRAPHY*
ROlHL-07379-13 Structure and function of fibrinogen
(human)
ROIHL 1828404 Aging erythrocytes -Bio-recognition and
elimination (monkeys)
** ROlHL-22355-01 Purification, structure and function of
factor VIII (human)
POlHL-22633-01 0002 Cellular and molecular biology of
lipoprotein metabolism - Sterol metabolism in tissue
culture cells
ROlHL-23981-01 Acute alveolar injury (dogs)
PHYSICAL SEPARATION, CHROMATOGRAPHY,
AFFINITY
** POlHL-15596-05 0003 Coagulation, fibrinolysis.
hemostasis and hepatitis • Plasmin degraded fibrinogen
fractions (human)
** P01HL15596-05 0020 Coagulation, fibrinolysis,
hemostasis and hepatitis - Affinity chromatography
ROlHL-1809504 Human dopamine-beta-hydroxylase (also
cattle)
ROlHL-2169202 Purification of erythropoietin (human)
ROlHL-22242-01 The converting enzyme of lung (cattle,
human)
PHYSICAL SEPARATION, CHROMATOGRAPHY,
AMINO ACID ANALYZER*
** ROIHL 11119-17 Amino acid analyzer for biochemical
research
PHYSICAL SEPARATION, CHROMATOGRAPHY,
DEAE CELLULOSE*
ROlHL-1477810 Proteolytic enzymes and inhibitors in
lung disease (mammals, human)
ROlHL-17710-04 Selective replication of hemoglobin genes
(mice, ducks, human)
PHYSICAL SEPARATION, CHROMATOGRAPHY,
GAS*
ROlHL-1388508 9002 Cystic fibrosis and pulmonary
disease - Computer core facility (human)
** P60HL- 17269-04 0016 National heart and blood vessel
research and demonstration center - New analytical
methodology for atherosclerosis studies
PHYSICAL SEPARATION, CHROMATOGRAPHY,
GEL FILTRATION (PERMEATION)*
ROlHL-18618-04 Purification and function of human HMW
kininogen
PHYSICAL SEPARATION, CHROMATOGRAPHY,
HIGH PRESSURE LIQUID*
** POlHL-08214-15 0047 Chemical and biological properties
of lipids - High resolution liquid chromatography for the
analysis of biological substances
" P60HL-17269 04 0016 National heart and blood vessel
research and demonstration center - New analytical
methodology for atherosclerosis studies
(contd)
•Excludes routine methodology OR covers only general proiects whicli preclude
**0nented signihcantly to above subject.
indexing at the specific level.
M Grant has subproiects descnbing specific research aspects.
See Appendix for investigators name and grant number.
PHY
PHYSICAL SEPARATION, CHROMATOGRAPHY,
ION EXCHANGE*
R01HL14680-07 Specific enrichment of myoglobins for
carbon 13 NMR (catacea)
ROlHL-19331-03 Hirudin isolation and utilization (leeches)
ROlHL-20751-01 High speed liquid chromatography of
hemoglobins (human)
PHYSICAL SEPARATION, CHROMATOGRAPHY,
THIN LAYER*
ROlHL-22039-02 ion transport in cardiac muscle (dogs,
rodents, cattle)
PHYSICAL SEPARATION, ELECTROFOCUSING*
ROlHL-02262-23 Mechanisms regulating plasma proteins
and solutes (human, dogs)
R01HH5817-06 Plasminogen activators from tissues
(human, pig, cattle)
ROlHL-22355 01 Purification, structure and function of
factor VIII (human)
PHYSICAL SEPARATION, ELECTROPHORESIS*
SEE ALSO IMIi/IUNOLOGICAL TESTS AND IMMUNOASSAY
IMMUNOELECTROPHORESIS*
SEE ALSO PHYSICAL SEPARATION, ELECTROFOCUSING*
ROlHL-11822-10 Biophysical studies of macromolecular
interactions (microorganism, human)
ROlHL-22325 01 Thermodynamics in respiratory protein
binding (human, trout)
PHYSICAL SEPARATION, ELECTROPHORESIS,
GEL*
POlHL-16137-05 0008 Alveolar biology - Macromolecular
events in pulmonary cells in toxic environments (animals)
ROlHL-17710-04 Selective replication of hemoglobin genes
(mice, ducks, human)
** POlHL-18574-03 0001 Lipoprotein methodology and
biomedical applications - Ultrarentrifugal and
electrophoretic lipoprotein methodology-Applications
'* POlHL-18574-03 0005 Lipoprotein methodology and
biomedical applications ■ Structure and function of
lipoproteins
ROlHL-22242-01 The converting enzyme of lung (cattle,
human)
ROlHL-22355-01 Purification, structure and function of
factor VIII (human)
POlHL-2263301 0002 Cellular and molecular biology of
lipoprotein metabolism - Sterol metabolism in tissue
culture cells
PHYSICAL SEPARATION, FRACTIONATION
(GENERAL)*
SEE ALSOBLOOD AND RE SYSTEM, BLOOD FRACTIONATION
** POlHL-16833-04 0004 Hemoglobin and red cell system in
hemoglobinopathies - Purification and fractionation of
hemoglobin A and S (human)
PHYSICAL SEPARATION, FRACTIONATION,
SOLVENT*
ROlHL-22035-01 Molecular modification of heparin by
chemical means (sheep)
PHYSICAL SEPARATION, MOLECULAR SIEVES*
ROlHL-18010-04 Capillary transport of large molecules
(dogs, sheep)
PHYSICAL SEPARATION,
ULTRACENTRIFUGATION*
ROIHL-1 1822-10 Biophysical studies of macromolecular
interactions (microorganism, human)
POlHL-14414-07 0014 Environmental influences on
cardiorespiratory and cellular functions - Temperature and
acid-base status in tissues, cells, and subcellular system
PHYSICAL SEPARATION,
ULTRACENTRIFUGATION, ANALYTICAL*
SEE ALSO PHYSICAL SEPARATION, ULTRACENTRIFUGATION,
DENSITY GRADIENT*
** POIHL-18574.03 0001 Lipoprotein methodology and
biomedical applications ■ Ultracentrifugal and
electrophoretic lipoprotein methodology-Applications
PHYSICAL SEPARATION,
ULTRACENTRIFUGATION, DENSITY GRADIENT*
POIHL 22633 01 0002 Cellular and molecular biology of
lipoprotein metabolism Sterol metabolism in tissue
culture cells
PHYSICAL THERAPY
SEE HEALTH CARE SERVICES, PHYSICAL THERAPY
PHYSICIANS
SEE HEALTH SCIENCES PROFESSIONS, PHYSICIANS
PHYSIOLOGICAL CHEMISTRY STUDY SECTION
** ROlHL-02477 23 Biosynthesis and function of lipids
(microorganisms, rats)
ROlHL-02751-21 Function and metabolism of serum
albumin (mammals, fish, amphibians)
ROlHL-02942-22 Biochemistry of cardiovascular connective
tissue (human, cattle, primates)
** R01HL04442-20 Mitochondrial assembly and replication
(fungi, wheat)
** R01HL0917215 Protein and RNA synthesis in heart
muscle (rats)
420
ROlHL-11551-11 RNA and protein synthesis in repair of
heart injury (mice, rats)
R01HL-12745-10 Enzymes and inhibitors of cholesterol
biosynthesis (rats, human, swine)
ROlHL-13630-08 Control of glycogen synthesis in heart
(cattle)
ROlHL-14778-10 Proteolytic enzymes and inhibitors in
lung disease (mammals, human)
ROlHL-1486507 Biochemical studies on the pathogenesis
of emphysema (human, rats)
ROlHL-15376-06 Intermediary metabolism of sterols (mice)
ROlHL-15979-05 Elastase, serum inhibitors and the
vasculature (human, swine)
ROlHL-1644505 Regulation of plasma protein
biosynthesis (rats, rabbits)
R01HL16512-04 Lipoprotein metabolism and hormonal
regulation (chickens)
ROlHL-16628-05 Regulation of lipid metabolism (rats)
ROlHL-16634-13 Regulation of metabolism in fibroblasts
and platelets (human, rabbits, sheep)
ROlHL-16920-02 Proteases in normal and immunologically
injured lung (guinea pigs, rabbits)
R01HL17194 03 Comparison of two inherited forms of
alpha 1-antitrvpsin (human)
ROIHL- 174 62-03 Role of glycosphingolipids in platelet
aggregation (rats, human, dogs)
R01HL17552-03 Sickling inhibition by chemical
modification of hemoglobin (human)
ROlHL-1 7783-04 Complex carbohydrates -Structure,
function, synthesis (swine)
ROlHL-17882-04 Regulation of HMG-COA reductase and
sterol synthesis (human, mammals)
ROIHL 1789803 Cell membranes and plasma lipoproteins
PHY
Chemical agents and heart glycolytic
(human, swine)
** ROlHL-17976-18
enzymes (sheep)
** R01HL-18089-04 Fatty acid metabolism in heart and its
regulation (swine, rats)
R01HL18181-04 Surfactant metabolism-Alveolar cells and
lung disease (mice, rabbits)
ROlHL-18625-03 Organization of arterial ground substance
(cattle)
ROIHL 18938-03 Pulmonary fatty acid and phospholipid
metabolism (rats)
** ROlHL-20794-02 Prostaglandin synthesis in human
platelets (also in sheep, rabbit)
ROlHL-21246-02 Roles of cholesterol and its metabolic
regulation (CHO cell mutants)
R23HL-2124702 Purification of renal renin (human)
** R23HL-21251-01 Metabolism of neutral lipids In the
pulmonary alveolus (rabbits)
ROlHL-21394-02 Pulmonary angiotensin-converting enzyme
(rabbits)
ROlHL-21471-02 Structure-function studies on actin and
myosin (human, protozoa, rabbits, cattle)
** ROlHL-21540-02 Specific inhibitors of coagulation and
fibrinolysis (rats, rabbits, dogs)
ROlHL-21628-02 Biosynthesis of lung surfactant lipid
(rabbit)
ROlHL-21831-05 Determining sequences from hemoglobin
messenger RNA (mice, chickens, rabbits)
R23HL-2I894-01 Pulmonary angiotensin converting enzyme
(cattle)
** ROlHL-21912-01 Biosynthesis of hpoic acid and
atherosclerosis (birds, chick embryos)
R23HL-2207501 Metabolism of arachidonic acid in blood
vessels (chickens, mammals)
ROlHL-22288-01 Renin and precursors-Structure and
function (mice)
ROlHL-2298301 Studies on the catabolism of plasma
lipoproteins (rats)
PHYSIOLOGY (GENERAL)*
SEE ALSO ELECTROPHYSIOLOGY
SEE ALSO NEUROPHYSIOLOGY (GENERAL)
SEE ALSO PSYCHOBIOLOGY. PSYCHOPHYSIOLOGY
** P01HL06664-17 0042 Cardiopulmonary function in
remediable vascular disease - Physiologic studies on vein
grafts (dogs)
POlHL-14388-07 0151 Regulation of the circulation in
pathological states - Catecholamine release in potassium
ion-free contractures in the caudal artery
POlHL-14388-07 0152 Regulation of the circulation in
pathological states - Ion flux alterations in caudal artery in
SHR
Regulation of the circulation in
Subcellular distribution of calcium
POlHL-14388-07 0153
pathological states -
(rats)
POIHL 14388-07 0154
pathological states -
contraction (rats)
POlHL-14388-07 0155
pathological states
Regulation of the circulation in
Energetics of smooth muscle
Regulation of the circulation in
Cardiopulmonary afferent activity,
carotid chemo-baroreceptor reflexes
POlHL-1438807 0156 Regulation of the circulation in
pathological states - Blood pressure with drinking to
intracranial angiotensin II injections (rats)
POlHL-14388-07 0157 Regulation of the circulation in
pathological states - Autoregulation of renal blood flow and
distribution in sodium excretion control
POlHL-14388-07 0159 Regulation of the circulation In
pathological states - Early drug and diet interventions and
blood pressure development (rats)
POlHL-14388-07 0195 Regulation of the circulation in
pathological states - General review of potential
pathophysiologic factors in spontaneous hypertension
ROlHL-17702-04
excitability
ROlHL-18260-04
tissue (cattle)
ROlHL-1967703
R13HL-22068-01
(California)
R13HL-2252501
Electro-optical dyes as probes of heart
Cyclic nucleotide metabolism in lung
Venous structure and function (dogs)
Conference on The Internal Environment'
Ion-pump in the erythrocyte (rabbits.
Membrane transport processes in red
International symposium on the
diaphragm (Virginia)
PHYSIOLOGY STUDY SECTION
ROlHL-00082-30 Transmembrane movements (barnacles,
frogs, rats)
** ROlHL-01974-24
guinea pigs)
** ROlHL-02228-24 Respiration, circulation, and heat
regulation in exercise (bird, mammals)
ROlHL-02888-22 Interrelationships of circulation and
respiration (opossum, cats)
** R01HL-04457-20 Cellular aspects of active transport (fish,
rabbits, anurans. turtles)
ROlHL-0772315 Reflex control of vascular capacitance in
shock
M R01HL-0990613
blood cells
R01HL1018213 Circulatory function and electrolytic
metabolism (dogs, human)
R01HL10503-13 Cardiac ion transport and ultrastructure
(rats, guinea pigs, rabbits)
R01HL-1I153-12 Quantitation of flow and solute flux in
microvessels (cats, rais)
ROlHL-12174-11 Ventilation/pcrfusion distribution in the
lung (human, mammals)
** ROlHL-1279209 Local control of the microcirculation
(hamsters, rats)
ROlHL-13237-09 Erythrocytes during early development
(human, animals)
** ROIHL 13256-08 Amino acid transport by red cell
membranes (pigeons)
R01HL13349-06 Analysis of activation process in heart
muscle (guinea pigs, rabbits, human)
ROlHL-13567-06 Ion transport across cell membranes
(human)
ROIHL 1392906 Single nephron response to chronic
obstruction (frogs, rats)
ROlHL-14523-07 Generation and regulation of force in
smooth muscle (animals)
** R01HL-14820-07 Factors affecting physiology of biological
membranes (human)
** ROlHL-15390-12
microcirculation
** R01HL15692-07
muscle
" ROlHL-15852-06
mechanisms
** ROlHL-1601016
(frogs)
** ROIHL-16430-05
** R01HL16606-11
muscles (frogs)
** ROlHL-16666-05
endothelium
** R01HL17702-04
excitability
** ROlHL-17715-04
respiratory control (cats)
** ROlHL-1784704
marmots
** R01HL17967-04
lung
** ROlHL-17998-04
circulation (dogs)
** R01HL18007-05
Regulation of blood flow in the
Force and speed in skeletal and cardiac
Vascular ion transport and hypertensive
Cellular basis of cardiac contractility
Neural control of respiration (cats)
Contraction in heart and other striated
Micropinocytosis in Isolated capillary
Electro-optical dyes as probes of heart
Respiratory muscle afferents in
(cats)
Cardiovascular and renal functions of
Limiting factors in oxygen uptake in the
Regulatory mechanisms in blood
Neural mechanisms confroling motor act
of breathing (cats, human)
ROlHL-18053-03 Intracellular ionic activities in heart
muscle (frogs)
ROlHL-18077-04 Smooth muscle cell organization and
Ca20 concentration control (chickens)
ROlHL-1829204 Vasodilation and microvascular oxygen
delivery (dog, hamster)
R01HL-1835I-03 Brain metabolism, acid-base balance.
and respiration
R01HL18489-03
chemicals (rats)
ROlHL-18676-03
ROlHL-18868-03
Hemodynamic interactions of vasoactive
Myocardial sarcomere mechanics (rat)
Development of vertebrate vascular
control systems (reptiles, amphibians)
ROlHL-1890003 Intercellular factors in function of
cardiac cells
ROlHL-1894303 Contractile activity of single cardiac cells
R01HL19008-02 Carbon dioxide diffusion in lung and
muscle tissues (dogs)
R01HL19082-01
smooth muscle
ROlHL-19138-03
Hypoxiainduced relaxation of vascular
Contractile activation of skinned cardiac
•Excludes routine methodology OR covers only general projects which preclude indexing
**Onented significantly to above subject.
at the specific level.
M Grant has subproiects describing specific research aspects
See Appendix for investigators name and grant number.
cells (mammals)
ROlHL-19320-03 Angiotensin neuropharmacology -
Relationship to sodium
ROlHL-19455-03 Role of endothelial cells in vascular
permeability (tissue culture)
(contd)
PHY
** R01HL1963902 P«ime«bilitY transients ol csfiieis.
chinnds and lieart
•* ROIHL 1999502 Sensocy tunsduction in caidiat
machanoteceptors (cats. Iiogs. tats)
•• ROIHI 2015302 Intracellulai pH and myocaidial
alecttophaimacology (dogs, guinea pigs)
*• ROIHI 2023002 Analysis ol the action potential of
cardiac muscle (sheep)
" ROIHL 20254 02 Piobes ot tieart and neive membianes
Fluorescent dyes
** ROlHL-20365 03 Molecular mechanisms ol anion transport
•• ROlHL-20558 02 Cardiac electrophysiology tllects of ions
and drugs
*• R01HL20605'02 Microvascular responses during intestinal
absorption (rats)
•• ROIHL 20613 02 Mechanical properties ol isolated
myocardium
•* ROIHL 20708 02 Voltage clamp ol embryonic heart cell
aggregates (rat and chick embryos)
** ROIHL 2071101 Structure function relationships in red
cell NA'K pumps (goats)
** ROlHL-2072502 Mechanisms and cellular functions of ion
transport
** R01HL21136-02 Ion activities and transport in cardiac
muscle cells (sheep)
" R23HL21150-02 Regulation ol airway mucous glands and
ion transport (dogs, ascaris)
** R01HL2117202 Regional oxygen consumption of heart
and other organs (animals)
" ROlHL-2117901 Volume regulation-Role of the membrane
potential (amphiuma)
** R23HL-2 12 13-01 A model tor calcium homeostasis in
excitable tissue (marine worms)
** ROlHL-2 125702 Breathing in sleep -Airway control and
blood gases (cats)
** ROlHL-2129402 Voltage clamp of isolated cardiac
Purkinje cells (dogs)
** ROlHL-21312-01 Sarcomere mechanics in disrupted
ventricular muscle (guinea pigs)
** R23HL-2 1434-02 Intrinsic control of coronary blood flow by
chemicals (guinea pigs)
** ROlHL-21922-01 Transient currents induced by
strophanthidin in the heart
•* R01HL-2223102 Modulation of calcium control of cardiac
myofibrils (rats)
•* ROlHL-22239-01 The molecular basis of electrical
excitability (chick embryos, rats)
** ROlHL-22258-01 New aspects of pharmacology related to
carbonic anhydrase
*• ROlHL-22264-01 Regulation of contraction in vascular
smooth muscle (dogs)
•* ROlHL-2242601 Initiation of the heartbeat -A voltage-
clamp study (bullfrogs, rabbits)
** ROlHL-2256101 Hormonal control of mesenteric
circulation (cats)
** ROlHL-22562-02 Mechanism of cardiac action potential
propagation (tunicates)
" ROlHL-2256902 Intestinal secretion -Capillary and tissue
forces (dogs, cats)
** ROlHL-22767-01 Model system tor cardiac action
potentials (squid, axons)
'• ROlHL-22845-01 Response of cardiac myosin to
hypertrophic stress (rabbits)
" ROlHL-23128-01 Cardiac contractility -Ischemia and
hypoxia (rabbits, rats)
*♦ ROlHL-23183-01 Voltage dependent conductance in
membranes
** ROlHL-2360101 Early hypoxia and development of
respiratory control
PHYSIOLOGY (APPLIED) AND ORTHOPEDICS
STUDY SECTION
M ROlHL-05883-18 Reflex control of resistance and
capacitance vessels
** ROlHL-06143-18 Response of the totally denervated heart
to exercise (dogs)
** ROlHL-1256409 Control of respiration and blood gases
(human, dog)
'* R01HL13233-08 Cardiorespiratory control in exercise
(human)
** ROlHL-13841-16 Respiration during altitude
acclimatization (goats, dogs, rats, rabbits)
** R01HL14102-07 Human physiology at 5360 meters -
Mountain environment
** ROlHL-14495-05 Solid and structural mechanics of lungs
(mammals)
** ROlHL-1485407 Lung and tissue mechanics (monkeys,
dogs)
** ROlHL-15469-06 Human ventilatory adaptation (also.
dogs, rats)
•* ROlHL-1602205 Determinants of the ventilatory response
to hypoxia (goats, cats)
" ROlHL-16254-05 Pathogenesis of bubble and clot
formation (fish)
** ROlHL-16390-05 Cardiopulmonary control coupling in
exercise (dogs)
** R01HL-16420-02 Effect of training-detraining on the rat
heart
** R01HL16784-03 Lung tissue and water volume (human.
dogs)
** ROlHL-16855-03 Cavitation in biological systems
(microorganisms, animals)
ROUU 1/352 03 Physiological regulation during chronic
hyperthermia (sheep)
ROIHL 1/40/ 05 Peripheral circulation and fluid balance
dish, mammals, human)
ROIHI 1/503 03 Vascular bubbles in decompression
sickness (minipig. dog, goat)
ROIHL 1/5/804 Exercise performance m children with
heart disease
ROIHL 1/604 03 Wearable blood pressure and tCG
recording system
ROIHL 17/3203 Peripheral venomotor control in thermal
stress (human)
ROIHL 1/9 70 04 Vascular effects of inhibitory behavioral
adaptations (dogs)
ROIHL 1845403 Maximal exercise testing in
hyperlipidemic children
' ROIHL 1852/ 03 Subcellular response of heart to
functional overload (hamsters, rats)
' R01HL1856003 Cardiovascular adaptation to stress
(miniature swine)
' ROIHL 18947-02 Indirect mean arterial pressure
(mammals)
' ROlHL-18984 01 P50 effect on exercise limit in stable
angina (human)
* ROlHL-191 18-03 Measurement of airways mechanics
(human, dog)
* ROIHL 19204 03 Environmental factors in hypertension
(Rhesus monkeys)
* ROIHL 19248-03 Breathing pattern variation and
mechanical influences
* ROIHL 19410-03 Dynamic interrelations underlying
exercise hyperpnea (human)
* ROlHL-19829-02 Power output of breathing (human)
* ROlHL-20187 01 Evaluation of exercise cardiac
rehabilitation program (40-55 year old men)
* ROlHL-20253-02 Effects of exercise on the heart and its
blood supply (dogs)
* ROlHL-20347-02 Bolus-response measurement of lung
function (human)
'* R01HL-2035102 A self-calibrating in vivo blood gas
monitor (dogs, infants)
•* R01HL-20373-02 Cardiovascular aging in young men and
women
" ROIHL 20634-01 Blood volume and venous return in
thermal strain (human)
** ROlHL-20663-02 Regulation of skin blood flow in man
** ROIHL 20678-02 Cardiovascular adaptation to stress in
disease states (dogs)
** ROlHL-20766-02 Control of circulation in heat stress
(baboons)
** ROlHL-20773-02 Surtactant, pulmonary edema, and lung
mechanics (rabbits)
** ROlHL-211 17-01 Altitude adaptation in chronic lung
disease (human)
" ROlHL-21 15902 Pathophysiological effects of hypoxia
(rats)
** R23HL-21199-02 Sound transmission in lung (dog)
•* ROlHL-21245-02 Influence of chronic exercise on
hypertension (rats, primates)
** ROlHL-21307-01 Risk reduction and exercise fitness in a
population
** ROlHL-21451-01 Control of circulation during heat stress
and fever (baboon)
" ROlHL-2 15 78-01 Effect of exercise upon the hypertensive
adolescent
** R23HL-21954-01 Exercise conditioning in patients with
cystic fibrosis
'* R23HL-21990-01 Accuracy of the ventilatory response to
exercise (dogs)
•♦ ROlHL-22154-01 Cardiac adaptation to physical training
(dog)
** ROlHL-222 15-01 Effects of exercise-training in ischemic
heart disease (human)
** ROlHL-22361-01 Regulation of cardiac adaptation to
exercise (rats)
** ROlHL-22406-01 Isobaric vascular bubbles and
decompression sickness (goats, models)
** ROlHL-23206-01 Repetitive exercise and cardiac
enlargement (dogs)
PHYSOSTIGMINE
SEE BENZOPYRROLES. PHYSOSTIGMINE
PHYTOAGGLUTININS
SEE PLANTS PROTEINS. LECTINS
PHYTOLACCA SP.
SEE PLANTS. ANGIOSPERMS. POKEW/EED*
PHYTOLACCACEAE
SEE PLANTS. ANGIOSPERMS, POKEWEED*
PHYTOMITOGENS
SEE PUNTS PROTEINS. LECTINS
PIA MATER
SEE NERVOUS SYSTEM CENTRAL. MENINGES. PIA MATER
PICROTOXIN
SEE TOXICOLOGY. PLANT POISONS. PICROTOXIN
PICTORIAL DATA PROCESSING (COMPUTER)
SEE OPTICS. IMAGE PROCESSING ANALYSIS AND DISPLAY-
PIGEON BERRY
Sfl PIAI^IS. ANGIOSPERMS. POKEWEtO*
PIGEONS
Sfl BIROS. PIGEONS'
PIGMENTATION, CHROMATOPHORES
POIHL 06285 18 0211 taidiova'-colar respiratory
physiology and biochemistry Purple membrane of
Halobacteria
PIGMENTS, BACTERIAL, BACTERIORHODOPSIN-
RETINAL
POIHI 06285 18 021 1 Cardiovascular respiratory
physiology and biochemistry Purple membrane of
Halobacteria
PIKAS
SEE MAMMALS. LAGOMORPHS*
PILLS
SEE DOSAGE FORMS
PINOCYTOSIS
SEE BIOLOGICAL TRANSPORT. ACTIVE TRANSPORT.
PINOCYTOSIS
PIPE SMOKING
SEE PSYCHOLOGY. HABITS. SMOKING
PIPERIDINES, FENTANYL
ROlHL-13257 09 Inhalation anesthesia on myocardial
metabolism (dogs, swine, human)
PIPERIDINES, HALOPERIDOL
R23HL 2230901 Cardiovascular pharmacodynamics in
immature dogs
PITCH
SEE PHYSICAL PROPERTIES. SOUND FREQUENCY
PITRESSIN
SEE PITUITARY-DIENCEPHALON HORMONES. VASOPRESSIN
PITUITARY-ADRENAL AXIS
R01HL-19644-03 Etiological factors in hypertension
(human, dogs, rats)
ROlHL-2086101 Cardio-respiratory-renal stress reactions
(dogs)
PITUITARY CACHEXIA
SEE PITUITARY GLAND DISORDERS. HYPOPITUITARISM
PITUITARY-DIENCEPHALON (HORMONES)
** POlHL-11678-11 0047 Cardiovascular dynamics and their
control ■ Unidentified pituitary factor in regulation of
aldosterone secretion (rats)
** ROlHL-20685-02 Pituitary adrenergicovarian vasomotor
interaction (dogs)
PITUITARY-DIENCEPHALON HORMONES, ACTH
R01HL02262-23 Mechanisms regulating plasma proteins
and solutes (human, dogs)
POlHL-0631417 0054 Immunologic mechanisms in
cardiovascular disease - Physiology of cell communications
(mice, frogs, guinea pigs)
POlHL-06835-17 0050 Cardiovascular disease - 18-
Hydroxylase block m the 17 alpha-hydroxylase deficiency
syndrome (human)
ROlHL-06975-18 Pathogenesis and prevention of
hypertension (rats)
R01HL0992113 Mechanisms related to congestive heart
failure (dogs, human, rat)
R01HL1104612 Renin, angiotensin, steroids, ions and
blood pressure (human, sheep, rabbits)
P01HL1167811 0046 Cardiovascular dynamics and their
control - Regulation of aldosterone secretion and related
factors (dogs)
ROlHL-12085-10 Lipoprotein-carbohydrate metabolism
(human, rats)
P50HL14214-07 0015 Newborn lung center for hyaline
membrane disease - Hormone effect on cyclic nucleotide
lipid synthesis in developing lung (animal)
** P50HL1421407 0024 Newborn lung center for hyaline
membrane disease - Synthesis and receptors for ACTH in
fetal lung (human)
P50HL1421807 0006 Pulmonary SCOR -Newborn lung
center - Biochemical characteristics of the lung in RDS
(human, sheep)
R01HL16037-06 Molecular properties of cardiac
adrenergic receptors
ROlHL-17749-03 Adrenocortical factors in human
hypertension (human)
ROlHL-1784704 Cardiovascular and renal functions of
marmots
P50HL-18323-04 0037 SCOR hypertension center •
Adrenocortical factors in childhood hypertension
ROlHL-18730-03 Role of mineralocorticoids in low renin
hypertension (human, rats)
R01HL18862-02 Thirst and its contribution to edema
(dogs)
ROlHL-20176-02 Biochemistry and genetics of salt
hypertension (rats)
POlHL-20948-02 0002 Molecular basis of cholesterol
metabolism - LDL pathway in cell lines with informative
properties other than fibroblasts
(contd)
■Excludes routine methodology OR covers only general proiects which preclude
"Oriented significantly to above subject.
ndexing at the specitic level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigators name and grant number.
PIT
ROlHL-2130801 Prostaglandins and local control of the
circulation (rats, dogs)
R23HL-21917-01 Adrenal steroids in adolescent and adult
hypertension
PITUITARY-DIENCEPHALON HORMONES, ACTH
INHIBITORS
SEE ALSO PYRIDINES, METYRAPONE
POlHL-11414-11 0014 Thrombosis and atherosclerosis
program - Role of adrenal in human essential hypertension
PITUITARY-DIENCEPHALON HORMONES, LH
RELEASING FACTOR
R01HL13909-27 Physiochemistiy and immunology of
macromolecules
PITUITARY-DIENCEPHALON HORMONES,
NEUROHYPOPHYSEAL HORMONES
SEE ALSO LIPID MOBILIZING FACTORS PITUITARY
SEE ALSO PITUITARY-DIENCEPHALON HORMONES. OXYTOCIN
SEE ALSO PITUITARY-DIENCEPHALON HORMONES,
VASOPRESSIN
POlHL-12738-10 0114 Physiologic pharmacology and its
clinical applications - Receptor specificites and metabolism
of neurohypophysial hormones (rats)
** POlHL-12738-10 0129 Physiologic pharmacology and its
clinical applications - Receptor specificities and
metabolism of vasopressin analogs
ROIHL- 180 15-03 Pharmacologic studies on vascular
smooth muscle (dogs, rats)
PITUITARY-DIENCEPHALON HORMONES,
OXYTOCIN
POlHL-12738-10 0129 Physiologic pharmacology and its
clinical applications - Receptor specificities and
metabolism of vasopressin analogs
ROIHL- 180 15-03 Pharmacologic studies on vascular
smooth muscle (dogs, rats)
ROlHL-20685-02 Pituitary-adrenergic-ovarian vasomotor
interaction (dogs)
PITUITARY-DIENCEPHALON HORMONES,
PITUITARY HORMONES
SEE ALSO LIPID MOBILIZING FACTORS PITUITARY
SEE ALSO PITUITARY-DIENCEPHALON HORMONES, ACTH
SEE ALSO PITUITARY-DIENCEPHALON HORMONES.
NEUROHYPOPHYSEAL HORMONES
SEE ALSO PITUITARY-DIENCEPHALON HORMONES, PROLACTIN
SEE ALSO PITUITARY-DIENCEPHALON HORMONES,
SOMATOTROPIN
SEE ALSO PITUITARY-DIENCEPHALON HORMONES,
THYROTROPIN
** ROlHL-19322-03 Role of pituitary hormones in the action
of vitamin K (rats)
PITUITARY-DIENCEPHALON HORMONES,
PROLACTIN
SEE ALSO PITUITARY-DIENCEPHALON HORMONES,
SOMATOTROPIN
SEE ALSO REPRODUCTIVE HORMONES, CHORIONIC
SOMATOMAMMOTROPIN
ROlHL-19056-03 Blood triglycerides and lipoprotein lipase
in the lung (rats)
ROlHL-214 18-02 Experimental myocardial infarction (rats)
PITUITARY-DIENCEPHALON HORMONES,
SOMATOTROPIN
SEE ALSO PITUITARY-DIENCEPHALON HORMONES, PROUCTIN
SEE ALSO PITUITARY GLAND DISORDERS, ACROMEGALY
SEE ALSO SKELETAL DISORDERS. BONE DEVELOPMENT.
DWARFISM. PITUITARY
ROlHL-09914-13 The myocardium in diabetes mellitus
(dogs, monkeys)
ROlHL-09921-13 Mechanisms related to congestive heart
failure (dogs, human, rat)
ROlHL-12085-10 Lipoprotein-carbohydrate metabolism
(human, rats)
ROlHL-13694-08 Capillary basement membrane in
cardiovascular disease (human, rats)
** ROlHL-191 75-03 Pituitary modulation of micro-and macro-
vascular disease (human, rats)
** POlHL-19717-02 0027 Response of the lung to injury •
Hormone control of lung growth and development (rats)
ROlHL-20364-01 Episodic hypertension associated with
human behavior (air traffic controllers)
** ROlHL-20517-03 Diabetes, somatotropin, factor VIII and
atherosclerosis (human, animal)
PITUITARY-DIENCEPHALON HORMONES,
THYROTROPIN
ROlHL-12085-10 Lipoprotein-carbohydrate metabolism
(human, rats)
PITUITARY-DIENCEPHALON HORMONES,
VASOPRESSIN
SEE ALSO METABOLIC DISORDERS (INBORN). DIABETES
INSIPIDUS
ROlHL-00340-29 Electrolyte disturbance m cardio-renal
disease (human, dogs, rats)
ROlHL-03181-21 0027 Hemodynamics as applied to
surgical problems • Hemodynamic studies of the Gl tract
(dogs)
422
ROlHL-05883-18 0001 Reflex control of resistance and
capacitance vessels - Naturally occurring vasoactive
substances and the vascular neuroeffectors (dog)
P0IHL-06285-I8 0196 Cardiovascular-respiratory
physiology and biochemistry - Hormonal regulation of
sodium transport -Epithelial cell membranes (toads)
" POlHL-06664-17 0038 Cardiopulmonary function in
remediable vascular disease - The dynamics of ADH-
stimulated osmotic water flow
POlHL-06664-17 0040 Cardiopulmonary function in
remediable vascular disease - The coupling of ion transport
to metabolism (toads)
POlHL-0868215 0027 Regulation of the cardiovascular
system - Cardiac mechanoreceptors -Reflex regulation of
renal function (dogs)
ROlHL-08893-14 Structure and function of membrane
proteins (human)
POlHL-10436-13 0014 A multidisciplinary study of
congenital heart disease - Cardiovascular pharmacology
(dog)
* POlHL-1 1678-11 Cardiovascular dynamics and their
control
•* POlHL-1 1678-11 0001 Cardiovascular dynamics and their
control - Body fluid volumes in the genesis of hypertension
(rats, dogs)
'* POlHL-1 1678-11 0027 Cardiovascular dynamics and their
control - Vasopressin and thirst in control of body fluid
volumes and osmolality (dogs)
POlHL-11678-11 0034 Cardiovascular dynamics and their
control - Renal function curves in intact dogs
'* POlHL-1 1678-11 0040 Cardiovascular dynamics and their
control - Control of plasma potassium concentration (dogs)
POlHL-11678-11 0046 Cardiovascular dynamics and their
control - Regulation of aldosterone secretion and related
factors (dogs)
POlHL-11678-11 0058 Cardiovascular dynamics and their
control - Overall control of the circulation -Computer
analysis
POlHL-1 1678-11 0059 Cardiovascular dynamics and their
control Basic hemodynamics (dogs, rats)
* POlHL-12738-10 0114 Physiologic pharmacology and its
clinical applications - Receptor specificites and metabolism
of neurohypophysial hormones (rats)
* POIHL 12738-10 0129 Physiologic pharmacology and its
clinical applications - Receptor specificities and
metabolism of vasopressin analogs
* ROlHL-12990-09 Control of antidiuretic hormone secretion
and metabolism (dogs, rats, rabbits)
ROIHL- 136 23-08 Atrial receptors (dogs)
ROlHL-14306-07 Quantification of arterial pressure control
(dogs)
POIHL- 143 88-07 0156 Regulation of the circulation in
pathological states - Blood pressure with drinking to
intracranial angiotensin II injections (rats)
POlHL-14388-07 0179 Regulation of the circulation in
pathological states - Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
POIHL-14388-07 0180 Regulation of the circulation in
pathological states - Regulation of cerebral blood flow
(dogs, monkeys)
* POlHL-14388-07 0183
pathological states
regulation (dogs, rats)
POlHL-14388-07 9002 Regulation of the circulation in
pathological states - Core immunoassay laboratory (rabbits)
ROlHL-15416-06 Cardiovascular control in normal and
disease states (dogs, baboons)
ROlHL-158 10-06 Electrolyte physiology and respiratory
acid-base (dogs)
ROlHL-16489-04 Renal prostaglandins-Synthesis and
function (human, dogs, rats)
ROlHL-17571-03 Study of membrane permeability by NMR
relaxation (human)
ROlHL-18015-03 Pharmacologic studies on vascular
smooth muscle (dogs, rats)
ROlHL-18020-04 Splanchnic hemodynamics in man
ROIHL- 180 96-04 Vasoactive agents in splanchnic viscera
(primates, dogs)
POlHL-18575-03 0005 Mechanisms of vascular changes
in hypertension - Renin synthesis in normotensive and
hypertensive pigs (also rats, dogs)
ROlHL-1886202
(dogs)
ROlHL-19039-03
model (dogs)
ROlHL-19057-03 Catecholamines and cyclic AMP in
cardiovascular system (rats, dogs)
ROlHL-19209-03 Role of ADH in experimental renal
hypertension (dogs, rats)
ROlHL-19287-03 The antihypertensive function of the
renal medulla (human, rats, rabbits)
ROlHL-19320-03 Angiotensin neuropharmacology-
Relationship to sodium
ROlHL-20685-02 Pituitary-adrenergic-ovarian vasomotor
interaction (dogs)
ROlHL-20768-02 Mechanisms of circulatory regulation in
heart failure (guinea pigs)
R0IHL-2086I-01
(dogs)
ROlHL-21094-01
(dogs)
Regulation of the circulation in
Vasopressin in cardiovascular
Thirst and its contribution to edema
Circulation studies by one vs two circuit
Cardio-respiratory-renal stress reactions
Arterial baroreceptors and renal function
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level
"Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects
See Appendix for investigator's name and grant number.
PLA
ROlHL-2127202 Sodium homeostasis and renal
prostaglandins (dogs)
ROlHL-2 1308-01 Prostaglandins and local control of the
circulation (rats, dogs)
** ROlHL-22051-01 Role of angiotensin II in vasopressin
release (human)
ROlHL-22069-02 Experimental renal arterial hypertension
(dogs)
ROlHL-22411-01 Neuroendocrine involvement In
hypertension (rats)
ROlHL-22561-01 Hormonal control of mesenteric
circulation (cats)
ROlHL-22617-01 Angiotensin, hypertension and the CNS
(sheep)
ROIHL 23602 01 Physiology of renin, aldosterone and
prostaglandin (human, rats, dogs)
PITUITARY-DIENCEPHALON HORMONES,
VASOPRESSIN, ARGININE VASOPRESSIN
ROlHL-02493-22 Kidney function in experimental heart
failure (dogs, rats)
ROlHL-17705-04 Kallikrein-kinin system in hypertension
(human, rats, dogs)
PITUITARY DWARFISM
SEE SKELETAL DISORDERS, BONE DEVELOPMENT. DWARFISM,
PITUITARY
PITUITARY GLAND
SEE ALSO PITUITARY-DIENCEPHALON (HORMONES)
** POIHL 16387-04 0009 The blood vessel and
thrombogenesis - Role of pituitary gland in the
pathogenesis of arteriosclerotic lesions (rats)
ROlHL-17847-04 Cardiovascular and renal functions of
marmots
PITUITARY GLAND, NEUROHYPOPHYSIS
POlHL-14388-07 0183 Regulation of the circulation In
pathological states - Vasopressin in cardiovascular
regulation (dogs, rats)
PITUITARY GLAND DISORDERS, ACROMEGALY
SEE ALSO PITUITARY-DIENCEPHALON HORMONES,
SOMATOTROPIN
ROlHL-20517-03 Diabetes, somatotropin, factor VIII and
atherosclerosis (human, animal)
PITUITARY GLAND DISORDERS,
HYPOPITUITARISM
SEE ALSO SKELETAL DISORDERS. BONE DEVELOPMENT.
DWARFISM. PITUITARY
ROlHL-00340-29 Electrolyte disturbance in cardio-renal
disease (human, dogs, rats)
ROlHL-20517-03 Diabetes, somatotropin, factor VIII and
atherosclerosis (human, animal)
PITUITARY HORMONES
SEE PITUITARY DIENCEPHALON HORMONES. PITUITARY
HORMONES
PITUITARY REMOVAL
ROlHL-19322-03 Role of pituitary hormones in the action
of vitamin K (rats)
PITUITARY-THYROID AXIS
R01HL-20861-01 Cardio-respiratory-renal stress reactions
(dogs)
PKG DEFICIENCY
SEE METABOLIC DISORDERS INBORN. PHOSPHOGLYCERATE
KINASE DEFICIENCY
PLACEBO EFFECT
SEE THERAPY. PLACEBO EFFECT
PLACENTA
SEE PREGNANCY. PLACENTA
PLACENTAL BARRIER
SEE PREGNANCY CIRCULATION. PUCENTAL TRANSFER
PLACENTAL CIRCULATION
SEE PREGNANCY CIRCUUTION
PLACENTAL CIRCULATORY DISORDERS
SEE PREGNANCY CIRCUUTORY DISORDERS
PLACENTAL HORMONES
SEE REPRODUCTIVE HORMONES. PLACENTAL HORMONES
PLACENTAL TRANSFER
SEE PREGNANCY CIRCULATION. PLACENTAL TRANSFER
PLANNING, FAMILY
SEE FAMILY PLANNING
PLANNING, REGIONAL MEDICAL
SEE HEALTH CARE (SERVICES)(RESOURCES)PLANNING.
REGIONAL MEDICAL PUNNING
PLANNING AND MANAGEMENT, PATIENT CARE
SEE HEALTH CARE SERVICES. PATIENT CARE MANAGEMENT.
PUNNING
PLANNING OF BIOMEDICAL RESEARCH
PROGRAMS
SEE HEALTH SCIENCES RESEARCH ANALYSIS-EVALUATION-
PUNNING
(contd)
i
v. •w^vcn
PtA
PLANNING OF EDUCATIONAL PROGRAMS
(SYSTEMS)
SEt EDUCATION PROGRAMS (SYSTEMS) EVALUATION
PUNNING
PLANNING OF HEALTH RESOURCES-SERVICES
SEE HEALTH CARE (StRVICESHRESOURCES) PLANNING
PLANT EXTRACTS
SEE PLANTS EXTRACTS
PLANT OILS (FATS)
SEE LIPIDS. OILS. VEGETABLE OILS
PLANTS (GENERAl)*
•• P01HL082U 1!> 0048 Chemical and biological properties
ot lipids Lipids in microorganisms and plants
PLANTS, ANGIOSPERMS (GENERAL)*
ROIHL 12971 15 Reactions of alholoids and their analogs
PLANTS, ANGIOSPERMS, ALLIUM*
R01HL19399 02 Atherosclerosis Early events and
regression factors (rats)
PLANTS, ANGIOSPERMS, LEGUMES, ALFALFA*
P01HL0683517 0064 Cardiovascular disease ■ Studies
in atherosclerosis (human, animals)
ROIHL 1658704 Cholesterol binding saponins and
atherosclerosis (monkeys)
PLANTS, ANGIOSPERMS, POKEWEED*
NOlHB-62962 02 Red cell distributions in cyanate treated
blood (human, sheep)
PLANTS, ANGIOSPERMS, RAGWEED*
P50HL1415307 0011 lohns Hopkins Lung Center-
Chronic diseases of airways - Allergy, airways reactivity
and asthma in human ragweed allergy
PLANTS, BRYOPHYTES, MOSSES*
PO1HL08214-15 0048 Chemical and biological properties
of lipids - Lipids in microorganisms and plants
PLANTS, FERNS*
P01HL08214-15 0048 Chemical and biological properties
of lipids ■ Lipids in microorganisms and plants
PLANTS EXTRACTS
SEE ALSO LIPIDS. OILS. CROTON OIL
SEE ALSO NATURAL PRODUCTS
SEE ALSO PLANTS PROTEINS
** R01HL-0750213 Phytochemistry of the genus thalictrum
(dogs, plants)
PLANTS EXTRACTS, MEDICINAL PLANTS
SEE ALSO BIOLOGICAL PREPARATIONS AND STANDARDIZATION
SEE ALSO CARBOHYDRATES. GLYCOSIDES
ROlHL-12971-15 Reactions of alkoloids and their analogs
PLANTS GROWTH REGULATORS
SEE ALSO PUNTS PROTEINS. LECTINS
P01HL08214-15 0030 Chemical and biological properties
of lipids ■ Fatty acid biosynthesis in plant cell cultures and
in plants
PLANTS PROTEINS
ROlHL-03299-21 Dietary effects on cholesterol metabolism
(rats, rabbits)
ROlHL-21483-01 Electronic, thermodynamic and kinetics
of hemoglobin
PLANTS PROTEINS, LECTINS
NOlHB-62962-02 Red cell distributions in cyanate-treated
blood (human, sheep)
ROlHL-0 1803-23 0015 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Immunologic endothelial iniury and lipid
diet atherosclerosis (rabbits, monkey)
ROlHL-05351 18 Blood group antigens and antibodies
(human, rabbits, sheep)
POlHL-0631417 0067 Immunologic mechanisms in
cardiovascular disease • Mitogenic and antigenic activation
of lymphocyte sub-populations
ROlHL-11154-12 Blood group antigens and antibodies
(human)
P50HL-14164-07 0044 A/S SCOR -Comparative and
experimental atherosclerosis - Cell biology-atherosclerosis
project (pigeons)
P50HL-18828-030006 Specialized center of researoh in
thrombosis - Etiology and pathogenesis of atherosclerosis
(rabbit, monkey, rat, human)
ROlHL-20971-10 Membrane glycoproteins of platelets and
leukocytes (human)
ROlHL-21692-02 Purification of erythropoietin (human)
** ROlHL-23010-01 Control and mechanism of platelet
aggregation (human)
PLANTS PROTEINS, LECTINS, CONCANAVALIN A
POlHL-03 174-23 0009 Mechanisms of acute vascular
reaction, to injury - Mast cell lipid interaction (human, rats)
POlHL-06314-17 0053 Immunologic mechanisms in
cardiovascular disease - Cellular functions controlled by
cyclic GMP (human, mice, guinea pigs)
POlHL-06314-17 0067 Immunologic mechanisms in
cardiovascular disease - Mitogenic and antigenic activation
of lymphocyte sub-populations
POIHL 06370 W 0004 Caidiopulniunjiy and umi.iI
pathology research center lymphocytes in graft reiection
and immune surveillance (human)
ROIHL 08696 lb 001? Orthotopic heart transplantation
Transplantation immunology Modulation ot donor
antigenicity (dogs)
ROIHL 08696 15 0013 Orthotopic heart transplantation
Transplantation immunology Cardiac heterotransplantation
(rabbits, dogs)
•* ROIHI 08696 15 0019 Orthotopic heart transplantation
Suppressor cell stimulation (dogs, mice)
POIHL 1741705 0001 Eipeiimental lung transplantation
Mechanisms and mediators of lung allograft rejection
(dogs, mice)
ROIHL 20971 10 Membrane glycoproteins of platelets anfl
leukocytes (human)
R23HL 2244801 Modulation ot heart graft antigenicity by
perfusion (rats)
PLASMA
SEE BLOOD AND RE SYSTEM. BLOOD. PUSMA
PLASMA AMINO ACIDS
SEE AMINO ACIDS. SERUM AMINO ACIDS
PLASMA KININ
SEE PEPTIDES. VASOACTIVE PEPTIDES, KALLIDIN
PLASMA LIPIDS
SEE LIPIDS BLOOD
PLASMA LIPOPROTEINS
SEE LIPOPROTEINS BLOOD
PLASMA MEMBRANE
SEE CELL COMPONENTS. CELL MEMBRANE
PLASMA PROTEINS
SEE BLOOD PROTEINS
PLASMA SUBSTITUTES
SEE BLOOD SUBSTITUTES. PUSMA SUBSTITUTES
PLASMA THROMBOPLASTIN ANTECEDENT
SEE BLOOD COAGUUTION. FACTOR XI
PLASMA THROMBOPLASTIN COMPONENT
SEE BLOOD COAGUUTION. FACTOR IX
PLASMA THROMBOPLASTINOGEN
SEE BLOOD COAGUUTION, FACTOR VIII
PLASMA THROMBOPLASTINOGEN B
SEE BLOOD COAGUUTION, FACTOR IX
PLASMALEMMA
SEE CELL COMPONENTS, CELL MEMBRANE
PLASMALOGENS
SEE PHOSPHOLIPIDS, PHOSPHOGLYCERIDES, PUSMALOGENS
PLASMAPHERESIS
SEE BLOOD TREATMENT, PUSMAPHERESIS
PLASMIN
SEE BLOOD COAGUUTION, PUSMIN
PLASMIN INHIBITORS
SEE BLOOD COAGUUTION, ANTIFIBRINOLYTIC AGENTS
PLASMINOGEN
SEE BLOOD COAGUUTION, PUSMINOGEN
PLASMINOGEN PROACTIVATOR ACTIVATORS
SEE BLOOD COAGUUTION, LYSOKINASE
PLASTICS
SEE ALSO PROSTHESIS
ROlHL-1 14 18-09 Poly-diaminophosphazenes
R01HL-17623-05 Initial events in thrombus formation on
surfaces (human, rats)
R23HL-21805-01 Tissue cell interactions with vascular
prostheses (human, rats, mice)
ROlHL-221 10-02 Healing complications in vascular
grafting (dogs)
PLASTICS, ACRYLIC POLYMERS
P50HL-191 70-02 0005 Harvard pulmonary SCOR -Chronic
diseases of the airways - Pulmonary toxicology of plastics
intermediates and pyrolysis products (animal)
R01HL-20O79-O2 0001 Thromboresistant material - Active
and passive thromboresistant surfaces
ROlHL-20079-02 0002 Thromboresistant material -
Thromboresistant materials (sheep)
PLASTICS, ACRYLIC POLYMERS, METHACRYLATES
ROIHL 15668 06 Extracorporeal respiratory gas exchange -
A new approach (dogs)
ROlHL-16921-05 Synthetic hydragels as blood tolerable
materials
ROlHL-17623-05 Initial events in thrombus formation on
surfaces (human, rats)
** ROlHL-20079-02 0001 Thromboresistant material - Active
and passive thromboresistant surfaces
ROlHL-20079-02 0003 Thromboresistant material ■ Blood
surface interactions (human, cattle)
ROlHL-2176901 Blood compatible benzaraidine containinf
polymers
PLASTICS, tLASTOMEBS
Sir AISOPIASIIC. RUBBIR
SEE AtSOPlASIICS, SIIICONI RUBBIR
POIHI 13738 08 0005 Cardiac aisi%l devitei and
artificial hearts Development of new materials tor
artificial heart and assist devices (sheep, dog)
POIHI 15195 04 0001 Program protect in biological
materials Design and synthesis
•• NOIHV 32949 11 Modification of silicon elastomers lor
medical devices , ,. ^ .
NOIHV 32959 10 Development ot materials lor heart asjiii
devices
NOIHV 72918 01 Test polymers for circulatory assist
devices
PLASTICS, FLUOROCARBON POLYMERS
POIHL 04664 18 0001 Cardiovascular and lung dynamics
X ray protection image videodensitometry (dogs)
POIHL 06370 17 0013 Cardiopulmonary and renal
pathology research center Morphologic analysis of
vascular prosthesis (human, dogs)
•• ROIHL 1671003 Myocardial subcellular localization ot
calcium (dogs)
ROIHL 1736904 Arterial bypass surgery Structure and
metabolism (monkeys)
ROIHL 17705 04 Kallikrein kinin system in hypertension
(human, rats, dogs)
P50HL 1917002 0005 Harvard pulmonary SCOK Chronic
diseases of the airways Pulmonary toxicology of plastics
intermediates and pyrolysis products (animal)
PLASTICS, NYLON
POlHL-13330 08 0056 Mechanical circulatory support -
Blood compatibility linings (calves)
ROlHL-21632 02 Development of a transcutaneous power
transfer system (cattle)
PLASTICS, POLYETHYLENES
POlHL-06664 17 0010 Cardiopulmonary function in
remediable vascular disease Ischemia and acute renal
failure (rats)
ROIHL 20079-02 0002 Thromboresistant material
Thromboresistant materials (sheep)
" ROlHL-21791 01 Precipitation of proteins with poly
(ethylene glycol) (human)
POlHL-22163-01 9001 Surface thrombogenesis-
Mechanisms and prevention - Polymers for studing blood-
material interactions core
PLASTICS, POLYETHYLENE TEREPHTHALATES
POlHL-13330-08 0056 Mechanical circulatory support
Blood compatibility linings (calves)
POlHL-13737-07 0002 Assisted circulation - U-shaped
mechanical auxiliary ventricle (dogs)
R01HL17973-04 Cultured aortic endothelial cells (human.
cattle, dogs, swine)
ROlHL-21632-02 Development of a transcutaneous power
transfer system (cattle) , u ^
NOlHV-12065-16 Fabrication of implantable artificial heart
devices (animals)
PLASTICS, POLYURETHANES
ROlHL-13803-07 Advanced cardiac valvular and vascular
prosthesis (dogs, baboons)
P50HL-19170-02 0005 Harvard pulmonary SCOR -Chronic
diseases of the airways Pulmonary toxicology of plastics
intermediates and pyrolysis products (animal)
ROlHL-20037-02 Left ventricular-aortic bypass and
composite prosthesis (sheep, swine, cattle)
** ROlHL-20079-02 0002 Thromboresistant material -
Thromboresistant materials (sheep)
ROlHL-20356-02 Development and evaluation of an
artificial heart (calves)
POlHL-22163-01 9001 Surface thrambogenesis-
Mechanisms and prevention - Polymers for studing blood-
material interactions core
R23HL-22895-01 Smoke inhalation-Biochemical and
cellular responses (rabbits, bacteria)
NOlHV-12017-15 Fabrication of grafted hydrogel coatings
for plastic heart assist devices
NOlHV-81388-20 Microfiber substrate for growth of intimal
linings in circulatory assist devices
PLASTICS, POLYVINYLS
SEE ALSO RUSTICS, POLYETHYLENES
SEE ALSO RUSTICS, STYRENE POLYMERS
** P50HL 19170-02 0005 Harvard pulmonary SCOR -Chronic
diseases of the airways - Pulmonary toxicology of plastics
intermediates and pyrolysis products (animal)
ROlHL-20079-02 0001 Thromboresistant material - Active
and passive thromboresistant surfaces
R23HL-22895-01 Smoke inhalation-Biochemical and
cellular responses (rabbits, bacteria)
PLASTICS, RUBBER
R23HL-22895-01 Smoke inhalation-Biochemical and
cellular responses (rabbits, bacteria)
PLASTICS, SILICONE RUBBER
ROlHL-1615405 Membrane lung perfusion for acute
respiratory failure (sheep, baboons)
. ROlHL-19055-03 Platelet function during extracorporeal
perfusion (human, mammals)
(contd)
•Excludes routine methodology OR covers only general projects which preclude
"Oriented significantly to above subject.
indexing at the specific level.
t* Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
PLA
ROlHL-20079-02 0002 Thromboresistant material ■
Thromboresistant materials (sheep)
ROlHL-21632-02 Development of a transcutaneous power
transfer system (cattle)
ROlHL-22888-01 Prosthetic valve endocarditis -Etiology
and therapy (dogs)
PLASTICS, STYRENE POLYMERS
SEE ALSO AMMONIUM QUATERNARY. CHOLESTYRAMINE
P50HL-19170-02 0005 Harvard pulmonary SCOR-Chronic
diseases of the airoays - Pulmonary toxicology of plastics
intermediates and pyrolysis products (animal)
R23HL-22895-01 Smoke inhalation-Biochemical and
cellular responses (rabbits, bacteria)
NOIHV-3295910 Development of materials for heart assist
devices
PLATELET ACTIVATING FACTOR
SEE BLOOD PUTELETS. PUTELET ACTIVATING FACTOR
PLATELET AGGREGATION
SEE BLOOD PLATELETS. PUTELET AGGREGATION
PLATELET AGGREGATION INHIBITORS
SEE BLOOD COAGUUTION. ANTICOAGUUNTS PLATELET
AGGREGATION INHIBITORS
PLATELET COFACTOR I
SEE BLOOD COAGULATION. FACTOR VIII
PLATELET FACTOR III
SEE BLOOD COAGUUTION. PUTELET FACTOR III
PLATELET PRESERVATION
SEE BLOOD PRESERVATION. PUTELET PRESERVATION
PLATELET TRANSFUSION
SEE BLOOD TRANSFUSION. PUTELET TRANSFUSION
PLATELET TYPING
SEE BLOOD PUTELET TYPING
PLATELETPHERESIS
SEE BLOOD TREATMENT. PUTELETPHERESIS
PLATINUM ELECTRODES
SEE ELECTRODES. PUTINUM*
PLATYRHINES
SEE MAMMALS. PRIMATES. MONKEYS AND APES
(ANTHROPOIDS. NON-HUMAN). NEW WORLD MONKEYS
(PUTYRHINES)*
PLEIOTROPISM
SEE GENETICS. GENES, GENE EXPRESSION. PLEIOTROPISM
PLETHORA
SEE CARDIOVASCUUR DISORDERS. HYPERVOLEMIA
PLETHYSMOGRAPHY
SEE CARDIOVASCUUR DISORDERS DIAGNOSIS
PLETHYSMOGRAPHY-
PLEURAL CAVITY
SEE BODY CAVITIES. PLEURAL CAVITY
PLEURAL DISORDERS
SEE BODY CAVITY DISORDERS. PLEURAL
PLEURAL EFFUSIONS
SEE BODY CAVITY DISORDERS. PLEURAL EFFUSIONS
PLEUROPNEUMONIA-LIKE ORGANISMS
SEE BACTERIA. MYCOPUSMATALES. MYCOPUSMA*
PLUMBISM
SEE METALS POISONING. LEAD POISONING
PMA (PHORBOL MYRISTATE)
SEE LIPIDS. OILS. CROTON OIL
PNEUMOANEMOMETER
SEE RESPIRATORY DISORDERS DIAGNOSIS. RESPIRATORY
AIRFLOW MEASUREMENTS*
PNEUMOCARDIOGRAPHY
SEE HEART DISORDERS DIAGNOSIS, PNEUMOCARDIOGRAPHY*
PNEUMOCOCCAL VACCINE
SEE VACCINES. BACTERIAL. PNEUMOCOCCAL VACCINE
PNEUMOCOCCUS
SEE BACTERIA, STREPTOCOCCACEAE. STREPTOCOCCUS
PNEUMONIAE*
PNEUMOCONIOSIS
SEE RESPIRATORY DISORDERS. PNEUMOCONIOSIS
PNEUMOCYSTIS PNEUMONITIS
SEE RESPIRATORY DISORDERS. PNEUMONIA PNEUMOCYSTIS
PNEUMOENCEPHALITIS VIRUS AVIAN
SEE VIRUSES. PARAMYXOVIRUSES. NEWCASTLE DISEASE
VIRUS
PNEUMOGRAPH
SEE RESPIRATORY DISORDERS DIAGNOSIS. PNEUMOGRAPH*
PNEUMONECTOMY
SEE RESPIRATORY SYSTEM SURGERY, PNEUMONECTOMY
^Excludes routine methodology OR covers only general projects which preclude indexing
Onented significantly to above subject.
424
PNEUMONIA
SEE RESPIRATORY DISORDERS, PNEUMONIA
PNEUMONIA ATYPICAL (PPLO)
SEE RESPIRATORY DISORDERS. PNEUMONIA MYCOPUSMAL
(PPLO)
PNEUMONIA BACTERIAL
SEE RESPIRATORY DISORDERS, PNEUMONIA BACTERIAL
PNEUMONIA PNEUMOCYSTIS
SEE RESPIRATORY DISORDERS. PNEUMONIA PNEUMOCYSTIS
PNEUMONIA VIRAL
SEE RESPIRATORY DISORDERS. PNEUMONIA VIRAL
PNEUMONITIS
SEE RESPIRATORY DISORDERS, PNEUMONIA
PNEUMONITIS, HYPERSENSITIVITY
SEE RESPIRATORY DISORDERS, PNEUMONITIS ALLERGIC
INTERSTITIAL
PNEUMORADIOGRAPHY
SEE RADIOGRAPHY, PNEUMORADIOGRAPHY*
PNEUMOTACHOGRAPHY, HEART
SEE HEART DISORDERS DIAGNOSIS, PNEUMOCARDIOGRAPHY*
PNEUMOTACHOGRAPHY, RESPIRATORY
SEE RESPIRATORY DISORDERS DIAGNOSIS. RESPIRATORY
AIRFLOW MEASUREMENTS*
PNEUMOTHORAX (GENERAL)
SEE BODY CAVITY DISORDERS, PLEURAL. PNEUMOTHORAX
(GENERAL)
POIKILOTHERMS
SEE TEMPERATURE (BODY). POIKILOTHERMS
POINT MUTATION
SEE GENETICS, MUTATION. GENE MUTATION. POINT
MUTATION
POISON CONTROL AND PREVENTION
SEE TOXICOLOGY. POISON CONTROL AND PREVENTION
POKEWEEDS
SEE PUNTS, ANGIOSPERMS. POKEWEED*
POLAR MOLECULES
SEE MOLECUUR POURITY
POLARCARDIOGRAPHY
SEE HEART DISORDERS DIAGNOSIS. POURCARDIOGRAPHY*
POLARIMETRY
SEE OPTICAL ROTATION*
POLARIZED PUMPING MEMBRANES
SEE BIOLOGICAL TRANSPORT. ACTIVE TRANSPORT ION
PUMPS
POLAROGRAPHY
SEE ELECTRICAL MEASUREMENTS. POUROGRAPHY*
POLLUTANTS, ENVIRONMENTAL (GENERAL)
SEE ENVIRONMENTAL HEALTH. CONTAMINATION (GENERAL)
POLLUTANTS INTERACTION
SEE PHYSICAL AND/OR CHEMICAL AGENTS INTERACTION
(BIOLOGICAL AND ECOLOGICAL). POLLUTANTS
INTERACTION
POLLUTION (GENERAL)
SEE AIR POLLUTION
SEE ENVIRONMENTAL HEALTH. CONTAMINATION (GENERAL)
SEE PHYSICAL PROPERTIES, SOUND, NOISE POLLUTION
POIYACETYLENES
SEE ALKYNES
POLYADENYLIC ACID
SEE PURINE NUCLEOTIDES. ADENINE NUCLEOTIDES
POLYADENYLIC ACID
POLY AMINES
SEE AMINES. POLYAMINES
POLYANIONS
SEE IONS, POLYIONS, POLYANIONS
POLYBROMINATED BIPHENYLS AND TRIPHENYLS
SEE HALOBENZENES, HALOGENATED BIPHENYLS-TRIPHENYLS
AND ANALOGS
POLYCHLORINATED BIPHENYLS AND
TRIPHENYLS
SEE HALOBENZENES, HALOGENATED BIPHENYLS-TRIPHENYLS
AND ANALOGS
POLYCHLORINATED DIBENZODIOXINS
SEE HALOBENZENES, HALOGENATED BIPHENYLS-TRIPHENYLS
AND ANALOGS
POLYCYCIIC HYDROCARBONS
SEE CYCLICS, CARBOPOLYCYCLICS
POLYCYTHEMIA
SEE BLOOD AND RE DISORDERS, BONE MARROW
POLYCYTHEMIA
POL
at the specific level.
M Grant has subprojeds describing specific research aspects
See Appendix for investigator's name and grant number.
POIYEIECTROLYTES
SEE IONS, ELECTROLYTES, POLYELECTROLYTES
POLYENES
SEE CHEMICAL BONDS, UNSATURATED COMPOUNDS
POLYENES
POLYETHYLENE TEREPHTHALATES
SEE RUSTICS, POLYETHYLENE TEREPHTHAUTES
POLYETHYLENES
SEE RUSTICS, POLYETHYLENES
POLYGLUTAMIC ACID
SEE PEPTIDES. HOMOPEPTIDES. GLUTAMYL
POLYLYSINE
SEE PEPTIDES. HOMOPEPTIDES. LYSINE PEPTIDES
POLYMERASES
SEE LIGASES
POLYMERIZATION
SEE MOLECUUR CONDENSATIONS. POLYMERIZATION-
DEPOLYMERIZATION
POLYMERS
SEE MOLECUUR CONDENSATIONS. POLYMERS (GENERAL)
POLYMORPHISM (BIOLOGY)
SEE BIOLOGY. POLYMORPHISM
POLYMORPHONUCLEAR LEUKOCYTES
SEE BLOOD CELLS. LEUKOCYTES. NEUTROPHILS
POLYNESIANS
SEE SOCIAL GROUPS. ETHNIC. POLYNESIANS
POLYNUCLEOTIDE LIGASE
SEE NUCLEIC ACIDS REPAIR. DNA REPAIR (ENZYME)
POLYNUCLEOTIDE LIGASE (NAD)
SEE NUCLEIC ACIDS REPAIR. DNA REPAIR (ENZYME)
POLYNUCLEOTIDE SYNTHETASE (ATP)
SEE NUCLEIC ACIDS REPAIR. DNA REPAIR (ENZYME)
POLYNUCLEOTIDE SYNTHETASE (NAD)
SEE NUCLEIC ACIDS REPAIR. DNA REPAIR (ENZYME)
POLYNUCLEOTIDES
SEE NUCLEOTIDES. POLYNUCLEOTIDES
POLYPEPTIDES
SEE PEPTIDES. POLYPEPTIDES
POLYPHENOL OXIDASE
SEE OXYGENASES. MONOPHENOL MONOOXYGENASE
POLYPHOSPHATES
SEE PHOSPHATES. POLYPHOSPHATES
POLYSACCHARIDE C-O LYASES, HEPARINASE
R01HL-17726-03 Bacterial heparinase in diagnostic
coagulation studies
POLYSACCHARIDE C-O LYASES, HYIURONATE
LYASE
ROIHL 19136-03 Mucopolysaccharide metabolism in
cardiac anomalies (rats)
POLYSACCHARIDES
SEE ALSO CARBOHYDRATES STRUCTURE. SUGAR SEQUENCE
POlHL-16769-05 0011 Pathobiologic and host defense
reactions in the lung - Core -Laboratory for biomedical
preparation (rabbits)
ROlHL-18607-03 Metabolic and drug studies on
experimental fat embolism (mice)
ROlHL-20910-02 The alternative diet for coronary disease
prevention (human)
ROlHL-21615-01 Structural studies of lung heparinoid
polysaccharides (cattle)
POLYSACCHARIDES, BACTERIAL (GENERAL)
SEE ALSO IMMUNOLOGY. ANTIGENS BACTERIAL
P60HL-1516207 0021 Comprehensive sickle cell center -
Pneumococcal vaccine in sickle cell disease (children)
P60HL-20985-01 0002 Northern California sickle ceil
center - Immunization with polyvalent pneumococcal
polysaccharide vaccine (human)
POLYSACCHARIDES, GLYCOSAMINOGLYCANS
SEE ALSO POLYSACCHARIDES. LIPOPOLYSACCHARIDES
ROlHL-02942-22 Biochemistry of cardiovascular connective
tissue (human, cattle, primates)
ROlHL-03299-21 Dietary effects on cholesterol metabolism
(rats, rabbits)
ROlHL-09914-13 The myocardium in diabetes mellitus
(dogs, monkeys)
ROlHL-10018-11 Effect of aging on beating heart cells m
culture (rats)
POlHL.11351-12 0004 Cellular and molecular
mechanisms of myocardial function - Molecular
mechanisms of contractile function and differentiation
(animals)
•* POlHL-13262-07 0018 Arterial wall in atherosclerosis -
Vasoactive factors of human plasma
POlHL-13262-07 0025 Arterial wall in atherosclerosis -
Phospholipid and cholesterol esters
(contd)
POl
•• PbOHL 14164 0/ 0029 Ays SCOR Comp»c«liv« and
upeiimental »th«ioscl«rosis Devolopraont ol pigeon
substiiins
PSOHL 14237 07 0002 Support lot trttnoscleiosis center
Intereclions ol lipoptolein particles with vascular surface
(human, rat)
PSOHL IblOi O; 0014 A/S SCOR Eatly natural history ol
arteriosclerosis Biochemistry ol atherosclerotic lesions
(monkeys, human, cattle)
•• ROIHL lilbbOb Rheology ol pulmonary secretions (dogs)
M POIHL 15832 06 Chemical structural predispositions to
lung iniury
POIHL 15832 06 0001 Chemical structural predispositions
to lung iniury Chemical composition ol lung connective
tissue proteins (human, animals)
POIHL 15832 06 0002 Chemical structural predispositions
to lung iniuiy Connective tissue in lung in development
and repair ol iniury (human, rats, mice)
POIHL 15832 06 0005 Chemical structural predispositions
to lung injury Pulmonary structure and stress strain
relationships (rats)
POIHL 1583206 0008 Chemical structural predispositions
to lung injury Interstitial fibrosis- Connective tissue
components in normal and diseased lungs
P01HL15835 06 0025 Study ol muscles related to heart
disease Cellular biology of vascular smooth muscle
(guinea pig)
P01HL1676905 0011 Pathobiologic and host delense
reactions in the lung Core -Laboratory lor biomedical
preparation (rabbits)
ROIHL 16955-05 Heparin, blood coagulation and lipid
metabolism (human)
ROlHL-17513-04 Role ol PF 4 in detecting and promoting
thrombosis (human, primates)
ROIHL 17865-04 Studies on aging -Effects of sex
hormones (rats, dogs)
•♦ ROIHL 17995-04 Cellular synthesis and release of
mucopolysaccharides (rabbits)
POIHL 18645-03 0001 Biology of the artery »»all and
atherosclerosis Primate arterial smooth muscle and
atherosclerosis
** ROIHL 18692-03 Glycosaminoglycans and lipoproteins ol
human plasma
ROlHL-187 14-04 Cardiovascular matrix -Morphogenesis
and maturation (human, chick embryo, mammal)
ROlHL-19252-02 Vascular connective tissue-Role in
atherosclerosis (rabbits)
ROlHL-19287 03 The antihypertensive function of the
renal medulla (human, rats, rabbits)
** ROlHL-19685-03 Pathogenesis of inflammation of the lung
(guinea pigs) . .
** POlHL-19717-02 0006 Response of the lung to injury -
Glycosaminoglycans and proteoglycans of the lung (human,
rats, hamsters)
POlHL-19717-02 0008 Response of the lung to injury ■
Experimental models of lung disease
POlHL-1971702 0022 Response of the lung to injury -
Localization of enzymes and sites of action in experimental
emphysema (hamsters)
POlHL-19717-02 0023 Response of the lung to injury ■
Postnatal lung development -Cells, connective tissue and
physiology (animals) _ .
P01HL1971702 0028 Response of the lung to injury ■
Compensatory grov.th of the lung following pneumonectomy
(rabbits)
** ROlHL-20447-03 Connective tissue and diabetic vascular
disease (human)
R01HL-21498-02 Pathophysiology of edema (rats, cats)
ROlHL-2159201 Lipoproteins and coagulation factors in
atherosclerosis (pigeons)
ROlHL-21612-02 Biochemistry of lung proteoglycans
(human, rabbits)
** ROlHL-21617-02 Biochemistry of lung proteoglycans
(rabbits, cattle)
ROlHL-21626-01 Proteoglycans of animal lung
parenchyma (cattle, pigs, rabbits)
" ROlHL-21641-02 Structural studies of lung proteoglycans
(pigs, cattle, rabbits)
ROlHL-21646-02 Biosynthesis of fractionated
proteoglycans of lung (rabbits)
ROIHL 21994-01 Structure and development of
regenerating capillaries (rabbits, chick embryo)
ROlHL-22583-02 Ultrastructural study of endothelium in
thrombosis (human)
ROlHL-22739-01 Evolution and progression of pediatric
atherosclerosis
NOlHV-42969-06 Interactions of natural and chemically
modified biopolymers with blood (dogs)
POLYSACCHARIDES, GLYCOSAMINOGLYCANS,
CHONDROITIN SULFATE
POlHL-11310-12 0104 Mechanisms of cardiovascular
disease - Structure of connective tissue proteoglycans
(rabbits)
P50HL-15103-07 0014 A/S SCOR -Early natural history ot
arteriosclerosis - Biochemistry of atherosclerotic lesions
(monkeys, human, cattle)
POlHL-15832-06 0001 Chemical-structural predispositions
to lung injury - Chemical composition of lung connective
tissue proteins (human, animals)
P50HL-17651-04 0045 Ischemic heart disease specialized
center of research - Peripheral vascular studies -
Pharmacology (dogs, human)
Alb
" ROIHL 19136 03 Mucopolysaccharide metabolism in
cardiac anomalies (rats)
ROIHL 19399 02 Atherosclerosis Early events and
regression factors (rats)
ROIHL 21612 02 Biochemistry ol lung proteoglycans
(human, rabbits)
ROIHL 21617 02 Biochemistry of lung proteoglycans
(rabbits, cattle)
NOIHV 42969 06 Interactions ol natural and chemically
modified biopolymers with blood (dogs)
POLYSACCHARIDES, GLYCOSAMINOGLYCANS,
DERMATAN SULFATE
ROIHL 20447 03 Connective tissue and diabetic vascular
disease (human)
ROIHL 21612 02 Biochemistry of lung proteoglycans
(human, rabbits)
R01HL2161702 Biochemistry of lung proteoglycans
(rabbits, cattle)
POIYSACC H ARIDES, GLYCOSAMINOGLYCANS,
HEPARAN SULFATE
POIHL 11310 12 0103 Mechanisms of cardiovascular
disease Heparin Metabolism and function
ROIHL 17995 04 Cellular synthesis and release of
mucopolysaccharides (rabbits)
ROIHL 19820 02 The chemistry and biological effects of
heparin (Rhesus, human, other mammals)
ROIHL 20447-03 Connective tissue and diabetic vascular
disease (human)
ROIHL 2161501 Structural studies of lung heparinoid
polysaccharides (cattle)
ROlHL-21617 02 Biochemistry of lung proteoglycans
(rabbits, cattle)
** ROlHL-21763-09 Heparin and heparan sulfate -Structure
and activity (beef, hog)
POLYSACC H ARIDES, GLYCOSAMINOGLYCANS,
HEPARIN
SEE ALSO BLOOD COAGULATION. HEPARIN CO-FACTOR
SEE ALSO LIPASES, LIPOPROTEIN LIPASE
ROlHL-01601-30 Blood coagulation and hemorrhagic
disease (horseshoe crabs)
ROlHL-02942-22 Biochemistry of cardiovascular connective
tissue (human, cattle, primates)
POlHL-03174-23 0009 Mechanisms of acute vascular
reaction to injury - Mast cell lipid interaction (human, rats)
POlHL-06285-18 0204 Cardiovascular-respiratory
physiology and biochemistry • Lipoprotein lipase and
triglyceride transport in chylomicrons (guinea pig. rat)
ROlHL-09739-13 Biophysical studies of proteins (human)
ROlHL-10582-12 Thrombosis and hemostasis -Analysis,
methods and standards (human, cattle, venom)
" P01HL-U310-12 0103 Mechanisms of cardiovascular
disease - Heparin -Metabolism and function
ROIHL 13626-06 Lipoprotein lipase and lipoprotein
removal (human, rats, bacteria)
POlHL-13738-08 0002 Cardiac assist devices and
artificial hearts - Total replacement with artificial heart
(calves, sheep, ponies)
POIHL- 137 38-08 0003 Cardiac assist devices and
artificial hearts - Pathophysiological effects of the artificial
heart (calves)
ROlHL-13754-08 Postoperative thromboembolism m
surgical patients (human)
P50HL-14147-08 0018 Specialized center of research in
thrombosis - Biochemical aspects of platelet function in
thrombosis and cell growth (human)
P5OHL-U187-07 0008 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses • Pulmonary
thromboembolism (dogs, human)
P50HL-14230-07 0098 A/S SCOR Lipids, atherosclerosis
and thrombosis Molecular properties of factor VIII (cattle,
human, mice)
** ROlHL-14992-07 Mechanism ot thrombin action (human)
POlHL-15486-06 0002 Studies on thrombosis -
Characterization of antisera to fibrinopeptide B (human,
rabbits)
POIHL- 154 86-06 0004 Studies on thrombosis -
Thrombosis, intravascuair coagulation, platelet aggregation
(dogs) ^ . ... . ,
POlHL-15486-06 0006 Studies on thrombosis - Clinical
investigation unit
ROlHL-15593-05 Prolonged extracorporeal cardiopulmonary
support (rats, sheep, rabbits)
** POlHL-15596-05 0017 Coagulation, fibrinolysis,
hemostasis and hepatitis - Heparin and antithrombin 111
ROlHL-15668-06 Extracorporeal respiratory gas exchangc-
A new approach (dogs)
ROlHL-15681-06 Coronary flow studies of partially
obstructed vessels (dogs)
ROlHL-16154 05 Membrane lung perfusion for acute
respiratory failure (sheep, baboons)
ROlHL-16582-05 Artificial lungs (dogs)
POlHL-16851-04 0008 Human red cell membrane in
health and disease - Force balance in red cell interactions
(human)
'* ROlHL-16955-05 Heparin, blood coagulation and lipid
metabolism (human)
ROlHL-175 13-04 Role of PF-4 in detecting and promoting
thrombosis (human, primates)
R01HL1772603 Bacterial heparinase in diagnostic
coagulation studies
HOIHI \iniUi Iniloll.ch^ii mfwi .mu r.-i.-..i-,„;
ROIHI 18068 0? Chemistry and activity of homologous
heparin fractions (rodents)
ROIHL 18333 05 Ihrombogeneiu and hemostatic balance
(rabbits, human)
POIHI 185/6 03 0013 Thrombosis reiearch program
project Early warning and moniloring lest jyjlemi in
thrombotic disease (human)
ROIHI 18590 03 Cerebral blood flow after cardiac arrest
(dogs, monkeys)
ROIHL 1860/ 03 Metabolic and drug studies on
experimental (at embolism (mice)
ROIHL 186/2 03 Dynamic studies of clot structure
formation (human)
ROIHL 18/64 03 Biosoibable IhromboresistanI surfaces
(dogs. rats, swine, human)
ROIHL 1881503 Surgical vascular disorders (human
dogs) ,
ROIHL 1905503 Platelet lunclion during extracorporeal
perfusion (human, mammals)
ROIHL 1910502 Detection and adherence of fibrin
monomer complexes (human)
R01HL19131 04 Hypercoagulability and assays lor its
protection (human)
P50HL 19153-02 0003 SCOR Pulmonary edemas Eitology,
pathogenesis Possible inhibitors of mediator release and
pulmonary vascular response (sheep)
ROlHL-19203-03 Surgical approach to congenital heart
diseases (dogs, primates)
** ROIHL 19820-02 The chemistry and biological elfecis ot
heparin (Rhesus, human, other mammals)
*• ROIHL 20079-02 0001 Thromborcsistant material Active
and passive thromboresistant surfaces
ROlHL-20079 02 0002 Thromboresistant material
Thromboresistant materials (sheep)
ROIHL 20251 02 A novel approach to nonthrombogenic
polymer surfaces (sheep, cattle)
ROIHL 20337-02 Thromboembolic diseases (human)
POlHL-20993 02 0007 Population dynamics of arterial
cells in alherogcnesis Interaction of lipoproteins in
hypercholesteremia (human, swine)
** ROlHL-21194-02 Development of antithrombogenic plastic
biomaterials
** ROlHL-21615-01 Structural studies of lung heparinoid
polysaccharides (cattle)
** ROlHL-21763-09 Heparin and heparan sulfate Structure
and activity (beef, hog)
** ROlHL-22035-01 Molecular modification of heparin by
chemical means (sheep)
ROlHL-22119-01 Biochemistry of platelet function in
thrombosis and cell growth (rabbits)
R01HL-22270-01 Platelet glycoprotein (human)
*• ROlHL-22402-01 Heparin-biophysical. chemical and
biological aspects (mice, human)
ROlHL-22967-01 Structure and function of heparin
releasabic lipases (swine, human)
ROlHL-23593-01 Mast cell granules -Structure and
secretion (rats)
** NOlHV-32919-12 Material development and testing
heparinization processes
NOlHV-42969-06 Interactions of natural and chemically
modified biopolymers with blood (dogs)
POLYSACCHARIDES, GLYCOSAMINOGLYCANS,
HYALURONIC ACID
P50HL-15103-07 0014 A/S SCOR -Early natural history of
arteriosclerosis Biochemistry of atherosclerotic lesions
(monkeys, human, cattle)
POlHL-16769-05 0010 Pathobiologic and host defense
reactions in the lung - Bronchus associated lymphoid
tissue and delayed hypersensitivity (rabbits)
POIHL-16769-05 0011 Pathobiologic and host defense
reactions in the lung • Core-Laboratory for biomedical
preparation (rabbits)
ROlHL-21649-01 Biochemistry of lung proteoglycans
(mammals)
NOlHV-42969-06 Interactions of natural and chemically
modified biopolymers with blood (dogs)
POLYSACCHARIDES, GLYCOSAMINOGLYCANS,
SULFOMUCOPOLYSACCHARIDES
SEE ALSO POLYSACCHARIDES. GLYCOSAMINOGLYCANS.
CHONDROITIN SULFATE
SEE ALSO POLYSACCHARIDES. GLYCOSAMINOGLYCANS.
DERMATAN SULFATE
SEE ALSO POLYSACCHARIDES, GLYCOSAMINOGLYCANS,
HEPARAN SULFATE
SEE ALSO POLYSACCHARIDES, GLYCOSAMINOGLYCANS,
HEPARIN
SEE ALSO PROTEOGLYCANS
ROlHL-21641-02 Structural studies of lung proteoglycans
(pigs, cattle, rabbits)
POLYSACCHARIDES, LIPOPOLYSACCHARIDES
SEE ALSO GLYCOLIPIDS
SEE ALSO IMMUNOLOGY. ANTIGENS MICROBIAL. ZYMOSAN
POlHL-06314-17 0067 Immunologic mechanisms in
cardiovascular disease - Mitogenic and antigenic activation
of lymphocyte sub-populations
R23HL-21212-02 Alveolar macrophage function in
Pseudomonas infection (dgs)
(contd)
•Excludes routine methodology OR covers only general proiects which preclude
"Oriented significantly to aliove subject.
indexing at the specific level.
H/l Grant has subprojects describing specific research aspects.
See Appendix for investigators name and grant number.
W':']
^.^M'l
'■, :•'-•'<■ '■•'h
■; ■■•.-.:;<?■
POL
POLYSACCHARIDES, SUIFOPOLYSACCHARIDES
SEE ALSO POLYSACCHARIDES, GLYCOSAMINOGLYCANS
SULFOMUCOPOLYSACCHARIDES
ROlHL-1 7597-05 Role of plasma lipoproteins in
atherosclerosis (swine, human)
POIYSOMES
SEE CELL COMPONENTS. POLYSOMES
POLYSTYRENES
SEE PUSTICS, STYRENE POLYMERS
POLYTETRAFLUOROETHYLENES
SEE PUSTICS, FLUOROCARBON POLYMERS
POLYUNSATURATED COMPOUNDS
SEE CHEMICAL BONDS. UNSATURATED COMPOUNDS
POLYENES
POIYURETHANES
SEE PUSTICS, POLYURETHANES
POLYVINYL ALCOHOLS
SEE PUSTICS, POLYVINYLS
POLYVINYL CHLORIDE
SEE PUSTICS. POLYVINYLS
POLYVINYLS
SEE PUSTICS. POLYVINYLS
PONS
SEE BRAIN, PONS
POPULATION GENETICS ANIMAL
SEE GENETICS, POPUUTION GENETICS ANIMAL
POPULATION GENETICS HUMAN
SEE GENETICS, POPUUTION GENETICS HUMAN
POPULATION STUDIES ANIMAL, EPIZOOTIOLOGY
ROlHL-19163-02 Piscine erythrocytic necrosis in the
Atlantic cod
ROlHL-1916403 Piscine erythrocytic necrosis in the
Atlantic cod
POPULATION STUDIES ANIMAL, LONGITUDINAL
STUDY
ROlHL-09914-13 The myocardium in diabetes mellitus
(dogs, monkeys)
P50HL-1413607 0001 Pulmonary SCOR-Airways
obstructive diseases ■ Experimental airway obstructive
disease (dogs)
P50HL-14164-07 0032 A/S SCOR -Comparative and
experimental atherosclerosis ■ Plasma cholesterol, lesion
regression and vascular function (Rhesus monkey)
R01HL-15797-05 Lipid metabolism and atherosclerosis in
primates (monkeys, human, squirrels)
R01HL-1620604 Regression of atherosclerotic plaques
(monkeys, dogs)
ROlHL-187 12-03 Iron deficiency-hyperlipidemia in
development (rats)
R01HL19I09-03 Regression of chronic atherosclerosis
(rabbits)
P5DHL-1936202 0001 A/S SCOR -Atherosclerosis in
nonhuman primates ■ Effects of infant nutrition on
atherosclerosis (baboons)
P50HL- 19362-02 0002 A/S SCOR -Atherosclerosis in
nonhuman primates - Infant caloric intake, adipose tissue
development and atherosclerosis (baboon)
P50HL- 19362-02 0003 A/S SCOR -Atherosclerosis in
nonhuman primates - Heritability of characters related to
atherosclerosis (baboons)
P50HL-19362 02 0012 A/S SCOR -Atherosclerosis in
nonhuman primates - Induction of chronic hypertension by
salt loading (baboon)
POIHL-20552-02 0002 The development and regression of
cardiac hypertrophy - Effect of treatment on the
hypertrophied left ventricle (rats)
ROlHL-20861-01 Cardiorespiratory-renal stress reactions
(dogs)
ROlHL-20895-03 0006 Cineangiographic studies of
cardiovascular system - Cardiomyopathy -Hemodynamic,
radiologic, morphologic abnormalities (dog. rabbit)
ROlHL-22661-01 Chronic total cardiopulhonary mechanical
substitution (sheep)
ROlHL-23201-01 Mechanisms of hypertension (human,
rats)
NOlHV-72933-01 Electrical energy transmission technique
development (dogs)
NOlHV-82919-00 Development of percutaneous energy
transmission systems
POPULATION STUDIES CELL
SEE ALSO CELL GROVin'H REGUUTION
SEE ALSO CELL MIGRATION
POlHL-03 174-23 0001 Mechanisms of acute vascular
reaction to injury - Response of the vascular intima to
injury (human, rats)
POlHL-03174-23 0006 Mechanisms of acute vascular
reaction to injury ■ Atherosclerotic plaque studies using
mosaic analysis (human)
P01HL-063I4 17 0052 Immunologic mechanisms in
cardiovascular disease • Role of cyclic nucleotides in
neutrophil function (human)
426
P01HL-06314-I7 0055 Immunologic mechanisms in
cardiovascular disease - Genetics and cell biology
P01HL12157-11 0055 Functions and mechanisms of cell
membrane ion transport - Growth and development of
synthetic strand heart cells in culture (chick embryo)
POlHL-13108-09 0016 Clinical heart transplantation -
Total lymphoid irradiation for immune response (dogs)
ROIHL 1323709 Erythrocytes during early development
(human, animals)
P50HL-142 12-07 0014 Correlated studies of pulmonary
fibrosis - Pulmonary lavage cells, secretions in diffuse
intersititial lung disease (human)
P50HL-14230-07 0099 A/S SCOR -Lipids, atherosclerosis
and thrombosis - Morphological, cytochemical study of
normal and altered vasculature (mice)
POlHL-14985-07 0010 Adaptation to hypoxia - Pulmonary
mast cell (animals)
P60HL-15996-06 0010 Cincinnati comprehensive sickle
cell center - W/hole blood viscosity in sickle cell anemia
(human)
P60HL-1600806 0014 VKayne State University
comprehensive sickle cell center Zinc and red blood cell
metabolism in sickle cell anemia (rats, human)
P60HL-1600806 0019 Wayne State University
comprehensive sickle cell center Cell mediated immunity
in sickle cell anemia (human)
ROlHL-16330-06 Aging-tissue injury and repair (rats)
ROlHL-167 11-05 RBC and endothelial membrane material
characteristics (human)
R01HL16714-05 Endothelial cell communication in
homeostasis (human, mammals)
R01HL17973-04 Cultured aortic endothelial cells (human,
cattle, dogs, swine)
R01HLI81 57-04 Subcellular events in atherosclerosis
(human, rabbits, calves)
ROlHL-18181-04 Surfactant metabolism-Alveolar cells and
lung disease (mice, rabbits)
ROlHL-18473-04 Genesis of atherosclerotic lesions
(human, mules)
POlHL-18645-03 0005 Biology of the artery wall and
atherosclerosis ■ Effects of atherosclerosis risk factors on
endothelium of the primate
ROlHL-1900903 Morphometric analysis of the sinoatrial
node (ferret)
ROIHL 19055-03 Platelet function during extracorporeal
perfusion (human, mammals)
R01HL19379-03 Characterization of small-granule cells in
the lung (mammals)
R01HL19651-03 Host factors in pathogenesis of
respiratory disease (human, hamsters)
ROlHL-19684-03 Histotypic lung culture in circumfusion
systems (mice)
ROlHL-20197-02 Maintenance and repair of vascular
endothelium (human, animals)
POlHL-20592-02 0010 Cell biology of cardiac and
skeletal muscle - Mitochondrial genesis during myocardial
cell hypertrophy and hyperplasia (rats)
ROlHL-20899-02 Cellular mechanisms of hemoglobin F
regulation (human)
M POlHL-20993-02 Population dynamics of arterial cells in
atherogenesis
** POlHL-20993-02 0001 Population dynamics of arterial
cells in atherogenesis - Arterial SMC population dynamics
in atherogenesis (swine)
" POlHL-20993-02 0002 Population dynamics of arterial
cells in atherogenesis - Arterial endothelial dynamics in
atherogenesis (swine)
** POlHL-20993-02 0003 Population dynamics of arterial
cells in atherogenesis - Clonal phenomena in atherogenesis
(human, hares)
POlHL-20993-02 0004 Population dynamics of arterial
cells in atherogenesis - Modifications of cholesterol balance
related to arterial cell divisions (swine)
POlHL-20993-02 0006 Population dynamics of arterial
cells in atherogenesis - Mechanism of regression of
atherosclerosis by diet and injury (swine)
POlHL-20993-02 0009 Population dynamics of arterial
cells in atherogenesis - Mathematical biology-Core
R23HL-21189-01 Regulation of pulmonary endothelial cell
activities (human, cattle)
ROlHL-21329-02 Beta-receptor regulation and cardiac
sites of drug action (cat. guinea pig. rat)
R23HL-21950-01 Endothelial cell mechanisms in vascular
disease (human)
ROlHL-221 19-01 Biochemistry of platelet function in
thrombosis and cell growth (rabbits)
ROlHL-2266401 Regulation of myocardial cell growth
(rats, guinea pigs)
ROlHL-23166-01 Pathology of mitochondria in ischemic
myocardium (rats, cattle)
R01HL-23232-01 Effect of hypoxia on PVSM and its
precursor cells
POPULATION STUDIES HUMAN
SEE ALSO ENVIRONMENT, ECOLOGY HUMAN
SEE ALSO FAMILY PLANNING
SEE ALSO GENETICS. POPUUTION GENETICS HUMAN
SEE ALSO SOCIOENVIRONMENT. RESIDENTIAL MOBILITY
MIGRANTS
ROIHL-17487-04 Adrenergic-vasoregulation interactions in
hypertension (human)
NOlHR-72973-01 Health education and attitudes of family
toward asthmatic children
POP
POPULATION STUDIES HUMAN, DEMOGRAPHY
ROIHL 1190112 0009 Effects of metabolic surgery on
the hyperlipidemias ■ Cholesterol cord blood and family
management program
** P60HL15162-07 0007 Comprehensive sickle cell center -
Core program -Demographic studies (human)
ROlHL-15614-04 Heredity and oxygen-Effects on health of
heart-lungs (South America)
R01HL1579O06 Follow-up study of acute coronary heart
attacks (human)
P60HL-17269-04 0043 National heart and blood vessel
research and demonstration center - Dietary modification-
Effect on cardiovascular risk parameters (human)
R25HL-18424-03 Blood pressure education in an industrial
setting (human)
ROlHL-1853503 Epidemiology and course of viral
myopericarditis (human)
ROlHL-18808-04 0001 Prediction and prevention of
sudden cardiac death - Prognostic significance of
premature ventricular contractions (human)
ROlHL-19877-02 Prevention of high blood pressure in
children
ROlHL-19956-03 High blood pressure in the young
(human)
NOIHR 72973 01 Health education and attitudes of family
toward asthmatic children
POPULATION STUDIES HUMAN, EPIDEMIOLOGY
SEE ALSO CARDIOVASCUUR DISORDERS EPIDEMIOLOGY
SEE ALSO DIAGNOSTIC SERVICES. MASS SCREENING
SEE ALSO EPIDEMIOLOGY AND DISEASE CONTROL STUDY
SECTION
SEE ALSO MENTAL HEALTH EPIDEMIOLOGY
SEE ALSO NEOPUSTIC DISEASE EPIDEMIOLOGY-STATISTICS
SEE ALSO NERVOUS DISORDERS EPIDEMIOLOGY
SEE ALSO RESPIRATORY DISORDERS EPIDEMIOLOGY
P60HL-15157-07 0001 Comprehensive center for sickle
cell disease - Screening program (human)
" P60HL-15160-07 0009 Center for sickle cell disease ■
Natural history of sickle cell disease (human)
P60HL-1516905 0012 Support for center for sickle cell
disease Evaluation of the incidence of cholelithiasis in
sickle cell disease (human)
ROIHL 16246-06 Immunologic studies in
postpericardiotomy syndrome (human)
P01HL16769-05 0007 Pathobiologic and host defense
reactions in the lung - Immunogenetic factors in
sarcoidosis (human)
ROlHL-19307-03 Problems in prevention of rheumatic
heart disease (human)
ROlHL-22838-01 Post-transfusion hepatitis in newborn
children
POPULATION STUDIES HUMAN, LONGITUDINAL
STUDY
NOlHB-6290807 Maternal to infant transmission of
hepatitis B (human)
R01HL-03429-18 Central nervous system and coronary
heart disease (human)
ROlHL-04651-19 Remote stimulation by radio-frequency
transmission (dogs, human)
R01HL04697-17 International heart disease epidemiology
(human)
POlHL-06285-18 0149 Cardiovascular-respiratory
physiology and biochemistry - Microangiopathy in
prediabetic and diabetic subjects (human)
POlHL-06312-17 0017 Surgical cardiology - Cardiac
transplantation (human)
ROlHL-08888-12 Cooperative study of drugs and coronary
heart disease (men)
POlHL-09011-15 0020 A research and resource program
in blood ■ Passive immunization in the prevention of
transmission of hepatitis B (human)
ROlHL-09474-11 Natural history-congenital heart defects-
Joint study (human)
R01HL09476-10 Natural history, congenital heart defects-
Joint study
ROlHL-10445-09 Cooperative study of drugs and coronary
heart disease (men)
ROlHL-10705-09 Cooperative study of drugs and coronary
heart disease (men)
ROlHL-10711-12 Cooperative study of treatment of
hypertension (human)
ROlHL-10718-10 Natural history of congenital heart
defects -Joint study (human)
** P01HL11310-12 0070 Mechanisms of cardiovascular
disease - Factors affecting long-term mortality and
morbidity after heart surgery (human)
ROIHL-11372-08 Cooperative study of drugs and coronary
heart disease (men)
ROIHL 11901-12 0001 Effects of metabolic surgery on
the hyperlipidemias - Partial ileal bypass (human)
R01HL11901-12 0018 Effects of metabolic surgery on
the hyperlipidemias - Jejunoileal bypass-Postoperative
complications (human)
POlHL-1237310 0002 Cardiopulmonary physiology and
pathophysiology - Determinants of performance of the
whole heart (dogs)
ROlHL-12542-07 Natural history, congenital heart defects-
Joint study (human)
ROlHL-12833-09 Genetic and environmental influences on
lung disease (human)
•EMiudes routine methodology OR covers only general projects which preclude indexing
Oriented significantly to above subject
at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
(contd)
POL
POlHL-13108'09 0001 Clinicil heart lucisplnntalion
Thttapy and proinosis (human)
RDIHL 13632 08 Vascular changes m diabetes meUilus
(human)
ROIHL 136M 08 Aniilipemic cejimes in penpheial
artenoscleiosis (human)
ROIHL 13694 08 CapillaiY basement membiane in
cacdiovasculai disease (human, lats)
ROIHL 1388508 000b Cystic tibiosis and pulmonaty
disease Evaluation ol lobat pulmonary lavage (human)
ROIHL 13885 08 0006 Cystic fibrosis and pulmonary
disease Cell mediated immunity and Pseudomonas
infections in cystic fibrosis (human)
ROIHL 1388508 9001 Cystic fibrosis and pulmonary
disease Pulmonary function core facility (infants,
children)
VI P50HL 1413607 Pulmonary SCOR Airways obstructive
diseases
P50HL 1413607 0003 Pulmonary SCOR Airways
obstructive diseases Acute pediatric respiratory disease
and COLD
P50HL 1413607 0009 Pulmonary SCOR-Airways
obstructive diseases Tuscon epidemiological study of
airvyays obstructive disease (human)
P50HL 1413607 0016 Pulmonary SCOR- Airways
obstructive diseases Environmental factors in airways
obstructive diseases (human)
P50HL 14136 07 0017 Pulmonary SCORAirways
obstructive diseases Pediatric airways obstructive disease
(human)
P50HL14138-05 0010 Center for research on
atherosclerosis Diet and exercise as therapy in men v»ith
premature atherosclerosis
P50HL 1414105 0001 SCOR tor atherosclerosis in
childhood Clinical implications (infants and children)
P50HL14141 05 0007 SCOR for atherosclerosis in
childhood Relation of lipid valves to sexual maturation at
puberty (human)
•* P50HL14153-07 0001 Johns Hopkins Lung Center-
Chronic diseases of airways - Genetic and environmental
factors in chronic pulmonary disease (human)
P50HL-14153-07 0010 Johns Hopkins Lung Center-
Chronic diseases of airways - Risk factors for ain«ays
obstruction in a rural community (human)
P50HL-14192-08 0001 Specialized center of research in
hypertension - Surgical and medical treatment of
renovascular hypertension (human)
P50HL-14192-08 0002 Specialized center of research in
hypertension - Hypertensive patients with renal artery
stenosis
P50HL 14212-07 0001 Correlated studies of pulmonary
fibrosis - Clinical studies core
** P50HL-142 14-07 0012 Newborn lung center for hyaline
membrane disease Pulmonary status of children who had
HMD as infants
** P50HL-142 14-07 0013 Newborn lung center for hyaline
membrane disease - Developmental outcome of children
who had HMD as infants
P50HL-14217-08 0063 Specialized center of research in
thrombosis - Special clinical studies laboratory
** P50HL-14218-07 0012 Pulmonary SCOR -Newborn lung
center - Longitudinal study of RDS -On-line fetal and
neonatal monitoring (human)
P50HL-14218-07 0013 Pulmonary SCOR -Newborn lung
center - Longitudinal study of RDS -Monitoring fetal P02
and PC02 during labor (human)
P50HL-14218-07 0014 Pulmonary SCOR -Newborn lung
center - Longitudinal study of RDS -Monitoring fetal
breathing movements (human)
** P50HL-14218-07 0015 Pulmonary SCOR -Nev«botn lung
center - Long term follow-up of infants surviving RDS -
Neurological outcome (human)
P50HL-14230-07 0088 A/S SCOR -Lipids, atherosclerosis
and thrombosis - Coronary risk factors in school children-
The Muscatine study
ROlHL-14262-07 Leukocyte proteases and their lung
targets (human, dogs, rabbits)
ROlHL-14378-07 Lipemias and reconstructive cardiac
surgery (human)
ROlHL-14692-06 Alpha 1 antitrypsin deficiency and
pulmonary disease (human)
ROlHL-14700-05 Humoral and lung protease-antiprotease
role in obstructive disease (human)
ROlHL-15047-06 Digital computer analysis of the
electrocardiogram (human)
** P50HL1 5092-07 0002 Immune and fibrotic response to
occupational environments - Longitudinal study of
sandblasters silicosis (human)
** P50HL-15092-07 0012 Immune and fibrotic response to
occupational environments - Longitudinal evaluation of
workers exposed to cotton dust
P50HL-1509207 0013 Immune and fibrotic response to
occupational environments - Epidemiology core resource
fyi P50HL-15103-07 A/S SCOR-Early natural history of
arteriosclerosis
** P50HL-15103-07 0001 A/S SCOR-Early natural history of
arteriosclerosis - Clinical research -Bogalusa heart study
(children)
ROlHL-1512405 Genesis of hypertension in renal disease
(human, dogs)
P60HL-15158-07 0012 Comprehensive sickle cell center -
Clinical services-Pediatric patients
427
P60HL 15160 0/ 0003 Center for sickle cell dis«i««
Genetic counseling in tiemoglobinopathies Dimensions,
effectiveness
' P60HI 15160 0/ 0009 Center for sickle cell disease
Natural history of sickle cell disease (human)
P60HI 151600/ 0015 Center for sickle cell disease
Lung function abnormalities in sickle cell
hemoglobinopathies (human)
P60HL 151620/ 000/ Comprehensive sickle cell center
Core program Demographic studies (human)
P60HL 15162 07 0018 Comprehensive sickle cell center
Biochemical and genetic studies of sickle cell anemia
(human)
P60HL 15162 07 0021 Comprehensive sickle cell center •
Pneumococcal vaccine in sickle cell disease (children)
P60HL 1516807 0005 Comprehensive sickle cell disease
center Ophthalmology (human, rabbits, monkeys)
P60HL 1516807 0010 Comprehensive sickle cell disease
center Sickle cell center project (children)
P60HL 1516905 0014 Support for center for sickle cell
disease Orthopaedic aspects of sickle cell disease
(human)
P60HL 1517005 0019 Support for center for sickle cell
anemia Renal handling of uric acid in sickle cell anemia
(human)
ROIHL 15174 06 CV disease epidemiology Second
generation studies (human)
ROIHL 15374 03 Cooperative study of drugs and coronary
heart disease (human)
P50HL 15389-07 0001 Pulmonary SCOR- Hypersensitivity
pneumonitis Clinical studies of hypersensitivity
pneumonitis
P50HL- 15389-07 0009 Pulmonary SCOR -Hypersensitivity
pneumonitis Clinical studies- Pulmonary mycotoxicosis
P50HL-15389-07 0010 Pulmonary SCOR-Hypersensitivity
pneumonitis Clinical study -Pulmonary lesions due to non-
invasive aspergillosis
ROIHL 1552605 Respiratory mechanics in children
ROlHL-15790-06 Follow-up study of acute coronary heart
attacks (human)
P60HL-15996-06 0001 Cincinnati comprehensive sickle
cell center Coagulation mechanisms in sickle cell disease
(human)
P60HL 15996-06 0003 Cincinnati comprehensive sickle
cell center Prophylactic penicillin in treatment of sickle
cell anemia (human)
P60HL- 15996-06 0005 Cincinnati comprehensive sickle
cell center Factors precipitating crises (human)
** P60HL-16005 05 0018 Comprehensive sickle cell center -
Comprehensive study-Natural history of sickle cell disease
in adults (human)
P60HL-1600505 0021 Comprehensive sickle cell center -
Management of pregnancy in sickle cell anemia (human)
P60HL-16008-06 0001 Wayne State University
comprehensive sickle cell center - Patient care system
(children, adults)
** P60HL-16008-06 0009 Wayne State University
comprehensive sickle cell center - Natural history of sickle
cell anemia (human)
ROlHL-16461-05 Late results of valve replacement -
Computer analysis (human)
ROlHL-16651-05 Evaluation of steroid therapy in
sarcoidosis (human)
P60HL1 7269-04 0004 National heart and blood vessel
research and demonstration center - Atherosclerosis-
Clinical surgical aspects (human)
ROlHL-17578-04 Exercise performance in children with
heart disease
P50HL-17648-04 0006 Study of ischemic heart disease -
Ventricular pertormance and myocardial perfusion in
obstructive coronary disease
P50HL-17651-04 0022 Ischemic heart disease specialized
center of research - Electrophysiology -Mechanism and
pharmacology of arrhythmias (human, dog)
P50HL-1765104 0048 Ischemic heart disease specialized
center of research - Noninvasive detection of ischemic
heart disease
P50HL17655-04 0004 Study of ischemic heart disease -
Coronary arteriography in survivors of acute myocardial
infarction (human)
P50HL-17655-04 0009 Study of ischemic heart disease -
Random trial of medical and surgical therapy in unstable
angina (human)
P50HL17665-04 0013 Study of ischemic heart disease -
National cooperative study in unstable angina pectoris
(human)
P50HL-17665-04 0018 Study of ischemic heart disease -
Computer correlation of data-Patients with ischemic heart
disease
P50HL-17665-04 0022 Study of ischemic heart disease -
Effect of coronary revascularization on left ventricular
function (human)
** P50HL-17667-04 0001 Study of ischemic heart disease •
Natural history of ischemic heart disease (human)
** P50HL-17667-04 0019 Study of ischemic heart disease -
Assessment of long-term results of coronary artery bypass
grafting (human)
P50HL-1767004 0012 Study of ischemic heart disease -
Epidemiology of sudden death (human)
P5CHL-17682-04 0001 Study of ischemic heart disease -
Studies in acute and chronic ischemic heart disease
(human)
POP
•• P50H1 1/682 04 OOOi Mudy of ischemii fie*r1 diitai*
[(teds of myocardial rev«»cul»ri/«lion in man
P50HI 1/68? 04 0008 Study of luhemic heart dittai*
Clinical core unit
ROIHI 1/993 04 0008 Ventricular dynimici from
surgically inserted markers Exercise after coronary bypau
(human)
ROIHI 1815/04 Subcellular events in alheroscleroiii
(human, rabbits, calves)
P50HL 18318 03 0018 Pathogeneiu and complicalioni ol
hypertension Plasma renin activity in chronic ischemic
heart disease (human)
•• P50HL 18323 04 0011 SCOR hypertension center
Endocrine profiling on a selected normal population
(human)
•• P50HL 1832304 0012 SCOR hypertension center Renin
as a risk factor (human)
•* P50HL 18323 04 0035 SCOR hypertension center ■ Control
of high blood pressure at the work site
ROIHL 1845403 Maximal exercise testing in
hyperlipidemic children
ROIHL 18456-03 Cardiovascular follow up ol hypertensive
adolescents
ROIHL 18589-03 Psychosocial factors and outcome in
coronary disease (human)
ROIHL 18632 02 Epidemiologic study of chronic lung
disease
R01HL1876904 Studies in survivors of lethal arrhythmias
(human)
** ROIHL 18776-04 Prevention of acute and fatal
cardiovascular disease (human)
ROIHL 18793 03 Clinical pathologic studies of sudden
cardiac death (human)
ROIHL 18794-04 Prospective studies of conduction disease
(human)
•* ROIHL 1880004 Prospective study of resuscitated sudden
death victims (human)
M ROIHL 18806-04 Sudden cardiac death and the onset ol
myocardial infarction
ROlHL-18805 04 0001 Sudden cardiac death and the
onset of myocardial infarction - Predictive value of
maximum exercise stress testing (human)
*• ROlHL-18805-04 0003 Sudden cardiac death and the
onset of myocardial infarction - Prediction from clinical and
laboratory assessments (human)
" ROlHL-18805-04 0004 Sudden cardiac death and the
onset of myocardial infarction Sudden death survivors--
Clinical follow-up and therapy (human)
ROlHL-18808-04 0001 Prediction and prevention of
sudden cardiac death - Prognostic significance of
premature ventricular contractions (human)
P50HL-19157-02 0008 Studies in cystic fibrosis and
bronchiolitis - Serum proteins in cystic fibrosis (human)
P50HL-19157-02 0011 Studies in cystic fibrosis and
bronchiolitis Pathogenesis of bronchiolitis (children)
** P50HL-19170-02 0001 Harvard pulmonary SCOR -Chronic
diseases of the airways - Natural history, reversibility of
pulmonary abnormalities in smokers (human)
M P50HL-19171-02 Pulmonary SCOR -Lung injury by
childhood infections
" P50HL19171-02 0001 Pulmonary SCOR -Lung injury by
childhood infections - Longitudinal study-Respiratory
infections and lung growth in normal children
** P50HL-1917102 0003 Pulmonary SCOR -Lung injury by
childhood infections - Natural history, host defense defects-
Children with chronic pulmonary disease
** P50HL-19171-02 0004 Pulmonary SCOR -Lung injury by
childhood infections - Long-term eftects of respiratory
infections in early childhood
P50HL-19171-02 0005 Pulmonary SCOR-Lung injury by
childhood infections - Chronic respiratory disease of
children in North Carolina
P50HL-19185-02 0009 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Nasal continuous positive
airway pressure in hyaline membrane disease (human)
" P50HL-19185-02 OOU Pulmonary SCOR-Neonatal
respiratory distress syndromes Complications and
sequelae of neonatal respiratory distress (human)
** P50HL-19187-02 0007 Pediatric pulmonary SCOR -Hyaline
membrane disease ■ Follow-up study-Infants with hyaline
membrane disease (human)
ROIHL 19567 03 Impact of emotion on coronary arteries
(human)
POlHL-19717-02 0038 Response of the lung to injury -
Interstitial lung disease-Clinical, pathologic and
epidemiologic
POlHL-19717-02 0043 Response of the lung to injury -
Asbestosis as a model of usual interstitial pneumonia
(human)
ROlHL-19839-09 Factors in youth predisposing to chronic
diseases (former college students)
ROIHL 19859-03 Epidemiological studies, precursors ol
hypertension (human)
** ROlHL-19864-03 0001 Blood pressure of children and
young adults - Follow up of students from Dormonl,
Pennsylvania
ROIHL 19869-03 Antecedents of adolescent hypertension
(human)
R01HL19898-03 Desferrioxamine therapy in thalassemia
(dogs, rats, children)
ROlHL-19922 03 Childhood determinants of blood pressure
(contd)
•Excludes routine methodology OR covers only general projects which preclude
••Oriented significantly to above subject.
indexing at the specific level.
1^ Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
POP
R01HL19929-03 High blood pressure in the young,
prevalence and precursors (human)
R01HL-I9946-03 Reduction of iron overload in
thalassemia (children, rabbits, dogs, monkeys)
ROlHL-19956-03 High blood pressure in the young
(human)
R01HL1996103 Management of hemosiderosis in
thalassemia (children, adults)
R01HL19962-03 High blood pressure in young people in
Tecumseh
ROlHL-2003702 Left ventricular-aortic bypass and
composite prosthesis (sheep, sv»ine. cattle)
ROlHL-20159-03 Genetic epidemiology of precursors of
hypertension (human)
R01HI.-2038103 Long-term study of diabetic vascular
disease (human)
ROlHL-20418-03 Serum cholesterol binding reserve in
diabetes (human)
ROlHL-20428-03 The juvenile diabetic heart (human)
ROIHL 20455-03 Role of systemic hypertension on diabetic
retinopathy (human)
ROlHL-20508-03 Diabetes, hyperglycemia and
cardiovascular disease (human)
ROlHL-2052203 Peripheral arterial disease in the diabetic
(human)
ROlHL-20535-02 Cardiovascular disease and evolving
diabetes mellitus (human)
ROlHL-20539-03 Blood glucose, hemoglobin Ale. and
diabetic vascular disease (human)
** R01HL-20637O2 Recovery after heart surgery -Bio-
behavioral factors (human)
ROlHL-20807-02 Detection of familial hypercholesterolemia
(human)
ROlHL-20829-02 Fluid mechanics of heart valve
prostheses (dogs, human)
ROlHL-20875-02 Chronic obstructive pulmonary disease-
Familial/genetic (human)
ROlHL-20910-02 The alternative diet for coronary disease
prevention (human)
P60HL-2098501 0002 Northern California sickle cell
center - Immunization with polyvalent pneumococcal
polysaccharide vaccine (human)
P50HL-21006-02 0001 Specialized center of research in
arteriosclerosis ■ Clinic and core program
P50HL-2100602 0002 Specialized center of research in
arteriosclerosis - Turnover and metabolism of cholesterol in
man
ROlHL-21010-02
40.000 persons
ROlHL-21293-02
surgery (human)
ROlHL-21352-02
disease (human)
ROlHL-21427-02
patients
ROlHL-2157201
syndrome
ROlHL-21829-01
Glycemia, other traits and CV death in
Randomized study of coronary bypass
Community studies of obstructive lung
Behavioral changes in post infarction
Natural history of the postphlebitic
Etiology of obstructive airway disease in
children (also monkeys)
R18HL-21906-01 Stanford five city multifactor risk
reduction study
ROlHL-21971-01 Atherosclerotic disease and risk factors
in twins (human)
ROlHL-22298-02 Origins of hypertension (human)
ROIHL-22976-01 Nonuniform ventilation and diffusing
capacity (human)
ROlHL-23078-01 Psychosocial stress and sudden coronary
death (human)
P60HL-23282-01 0002 Comprehensive hospital/community
sickle cell center - Clinical evaluation of alternate
pathaway of compliment activation
P60HL-23282-01 0004 Comprehensive hospital/community
sickle cell center • Bacterial, viral and mycoplasmal
infections and sickle cell disease complications
ROlHL-23970-01 Mechanisms and control of sudden
cardiac death (human, dog)
NOlHR-3290009 Pilot study to standardize the
measurement of 'closing volume' (human)
NOIHR-32902-07 Pilot study to standardize the
measurement of closing volume (human)
NOlHR-32903-11 Pilot study to standardize the
measurement of 'closing volume' (human)
N01HV1215810 Establishment of a lipid research clinic
NOlHV-12160-15 Establishment of a lipid research clinic
NO IHV- 12440- 14 Therapy for hypertension in the general
population (human)
NOlHV-2291711 Lipid research cimic (human)
' NOlHV-22939-12 Hypertension detection and follow-up
program center
N01HV-5290I-06
NOlHV-5294104
study (human)
NOlHV-52971-06
study cohort
NOlHV-62900-00
(human)
NOlHV-6295504 Data collection in clinical pathology and
morbid anatomy (men)
NOlHV-72915-02 Therapy for hypertension in the general
population
NOlHV-72984-03 High blood pressure control program
(human)
Aspirin-myocardial infarction study
Center for aspirin-myocardial infarction
Reexamination of Framingham heart
Study of breast cancer and reserpine use
NOlHV-72986-02
(human)
NOlHV-72987-02
(human)
NOlHV-72989-02
(human)
N01HV-72990-00
(human)
428
High blood pressure control program
High blood pressure control program
High blood pressure control program
High blood pressure control program
POPULATION STUDIES HUMAN, MORBIDITY
ROlHL-03341-22 Epidemiology of atherosclerosis in Evans
Co Georgia
POlHL-1131012 0068 Mechanisms of cardiovascular
disease - Pharmacological intervention and myocarcial
oxygen consuption (human, dogs)
** POlHL-1 13 10-12 0069 Mechanisms of cardiovascular
disease - Factors affecting mortality and morbidity after
heart surgery (human)
** POlHL-11310-12 0070 Mechanisms of cardiovascular
disease - Factors affecting long-term mortality and
morbidity after heart surgery (human)
POlHL-12738-10 0117 Physiologic pharmacology and its
clinical applications Ventricular arrhythmias in ischemic
heart disease (human)
P60HL-15162-07 0007 Comprehensive sickle cell center ■
Core program-Demographic studies (human)
P60HL-1599606 0003 Cincinnati comprehensive sickle
cell center - Prophylactic penicillin in treatment of sickle
cell anemia (human)
P60HL16005-05 0021 Comprehensive sickle cell center -
Management of pregnancy in sickle cell anemia (human)
P50HL18323-04 0035 SCOR hypertension center ■ Control
of high blood pressure at the work site
ROlHL-18632-02 Epidemiologic study of chronic lung
disease
ROlHL-18776-04 Prevention of acute and fatal
cardiovascular disease (human)
ROlHL-1880004 Prospective study of resuscitated sudden
death victims (human)
R01HL-i9839-09 Factors in youth predisposing to chronic
diseases (former college students)
ROlHL-20508-03 Diabetes, hyperglycemia and
cardiovascular disease (human)
R18HL-2190601 Stanford five city multifactor risk
reduction study
ROlHL-22255-01 The etiology/prevalence of peripheral
arterial disease (human)
N01HV-2293M4 Therapy for hypertension in general
population
NOlHV-2293707
population
NOlHV-22938-11
population
NOlHV-72984-03
(human)
NOlHV-72986-02
(human)
NOlHV-72987-02
(human)
NOlHV-72989-02
(human)
NOlHV-72990-00
(human)
Therapy for hypertension in general
Therapy for hypertension in general
High blood pressure control program
High blood pressure control program
High blood pressure control program
High blood pressure control program
High blood pressure control program
POPULATION STUDIES HUMAN, MORTALITY
SEE ALSO CHILDREN, INFANT AND CHILD MORTALITY
ROlHL-03341-22
Co Georgia
Epidemiology of atherosclerosis in Evans
International heart disease epidemiology
* ROlHL-04697-17
(human)
ROlHL-08888-12 Cooperative study of drugs and coronary
heart disease (men)
ROIHL-1044509 Cooperative study of drugs and coronary
heart disease (men)
R01HL10705-09 Cooperative study of drugs and coronary
heart disease (men)
POlHL-11310-12 0067 Mechanisms of cardiovascular
disease - Cardiac performance with measured
hemodynamic variables (human)
POlHL-11310-12 0068 Mechanisms of cardiovascular
disease - Pharmacological intervention and myocarcial
oxygen consuption (human, dogs)
' POlHL-1 13 10-12 0069 Mechanisms of cardiovascular
disease • Factors affecting mortality and morbidity after
heart surgery (human)
' POlHL-11310-12 0070 Mechanisms of cardiovascular
disease - Factors affecting long-term mortality and
morbidity after heart surgery (human)
POlHL-1 13 10-12 0082 Mechanisms of cardiovascular
disease - Myocardial function in adult congenital heart
disease (human)
ROlHL-11372-08 Cooperative study of drugs and coronary
heart disease (men)
ROlHL-13974-07 Ventricular premature beats and sudden
coronary death (human)
ROlHL-14131-18
(human)
R0IHL15790-06
attacks (human)
ROlHL-17580-04
disease (men)
P50HL17667-04 0001 Study of ischemic heart disease
Natural history of ischemic heart disease (human)
Abnormal hemoglobin syndromes
Follow-up study of acute coronary heart
The impact of stress on coronary heart
POP
P50HL-1 7667-04 0019 Study of ischemic heart disease ■
Assessment of long-term results of coronary artery bypass
grafting (human)
P50HL-18323-04 0035 SCOR hypertension center - Control
of high blood pressure at the work site
ROlHL-18632-02 Epidemiologic study of chronic lung
disease
ROlHL-18776-04 Prevention of acute and fatal
cardiovascular disease (human)
ROlHL-18800-04 Prospective study of resuscitated sudden
death victims (human)
R01HL18805-04 0003 Sudden cardiac death and the
onset of myocardial infarction - Prediction from clinical and
laboratory assessments (human)
R01HL18808-04 0001 Prediction and prevention of
sudden cardiac death - Prognostic significance of
premature ventricular contractions (human)
ROlHL-19073-02 Heart disease and drinking water at
home
ROlHL-1983909 Factors in youth predisposing to chronic
diseases (former college students)
ROlHL-20508-03 Diabetes, hyperglycemia and
cardiovascular disease (human)
' ROlHL-21010-02
40.000 persons
ROlHL-21088-02
stroke in Utah
R18HL-21906-01
reduction study
ROlHL-21971-01
in twins (human)
ROlHL-22255-01 The etiology/prevalence of peripheral
arterial disease (human)
ROlHL-22982-01 Multicenter postcoronaiy risk
stratification program (human)
NOlHV-12434-11 Therapy for hypertension in the general
population
NO IHV- 12436- 15 Hypertension therapy in the general
population (human)
NOlHV-12440-14 Therapy for hypertension in the general
population (human)
NOlHV-1244214 Therapy for hypertension in the general
population (human)
NOlHV-2293114
population
NOlHV-22937.07
Glycemia, other traits and CV death in
Genetic patterns in deaths from Ml and
Stanford five city multifactor risk
Atherosclerotic disease and risk factors
population
NOlHV-22938-11
population
NOlHV-22945-11
Therapy for hypertension in general
Therapy for hypertension in general
Therapy for hypertension in general
Cooperative hypertension detection and
follow-up study (human)
N01HV5290106 Aspirin-myocardial infarction study
Center for aspirin-myocardial infarction
NASNRC twin registry
Data collection in clinical pathology and
men)
High blood pressure control program
High blood pressure control program
High blood pressure control program
High blood pressure control program
High blood pressure control program
Therapy for hypertension in the general
^Excludes routine methodology OR covers only general projects which preclude indexing at the specific level
Onented sijniticantty to above subject
M Grant has subprojeds describing specific research aspects
See Appendix for investigators name and grant number.
NOlHV-52941.04
study (human)
NOlHV-53010-03
NOlHV-6295504
morbid anatomy (men)
NOlHV-72984-03
(human)
NOlHV-72986-02
(human)
NOlHV-72987-02
(human)
NOlHV-72989-02
(human)
NOlHV-72990-00
(human)
NO lHV-829 15-01
population (human)
POPULATION SURVEYS
P60HL- 17269-04 0043 National heart and blood vessel
research and demonstration center - Dietary modification-
Effect on cardiovascular risk parameters (human)
R23HL-22947-01 Experimental systems to improve youth
behavior (smoking prevention)
POPULATION SURVEYS, HEALTH SURVEYS
ROIHL-03341-22 Epidemiology of atherosclerosis in Evans
Co Georgia
ROlHL-03429-18 Central nervous system and coronary
heart disease (human)
ROlHL-13974-07 Ventricular premature beats and sudden
coronary death (human)
P50HL-1413607 0009 Pulmonary SCOR-Airways
obstructive diseases • Tuscon epidemiological study of
airways obstructive disease (human)
P50HL-14I36-07 0016 Pulmonary SCOR-Airways
obstructive diseases - Environmental factors in airways
obstructive diseases (human)
P50HL14153-07 0010 Johns Hopkins Lung Center-
Chronic diseases of airways • Risk factors for airways
obstruction in a rural community (human)
P50HL-14230-07 0088 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Coronary risk factors in school children-
The Muscatine study
POlHL-14388-07 9004 Regulation of the circulation in
pathological states - Core biostatistics unit
P50HL-15103-07 0001 A/S SCOR -Early natural history of
arteriosclerosis • Clinical research-Bogalusa heart study
(children)
P60HL15168-07 0003 Comprehensive sickle cell disease
center - Sickle cell education and training program
(contd)
POR
•• R01Hllb6U04 Heredity and oiygenfthcts on health ol
heart lungs (South America)
PSOHL 18318 03 0012 Pathogenesis and complications ol
hypertension Behavioral (actors in hypertension (human)
•* PbOHl 19in0? 000b Pulmonary SCOR lung iniury by
childhood mlcctions Chronic respiratory disease ol
children in North Carolina
*• ROIHL 19839 09 Factors in youth predisposing to chronic
diseases (tormcr college students)
ROIHL 19864 03 0001 Blood pressure o( children and
young adults Follow up o( students Irom Dormont,
Pennsylvania
•• R18HL 21906 01 Stanford live city multitactor risk
reduction study
R01HL2221201 Alameda county high blood pressure
control program
ROIHL 22380 01 Detroit hypertension control program
NOIHR 72974 01 Sell-management systems for asthmatic
children
NOIHV 1215714 Lipid research clinic (human)
NOIHV 1244014 Therapy lor hypertension in the general
population (human)
*• NOlHV-52971-06 Reexamination ol Frammgham heart
study cohort
PORPHYRIA
SEE UrtETABOLIC DISORDERS (INBORN). PORPHYRIA
PORPHYRIA, PROTOPORPHYRIA
SEE METABOLIC DISORDERS INBORN. PORPHYRIA.
PROTOPORPHYRIA
PORPHYRINS
SEE ALSO HEME
SEE ALSO METABOLIC DISORDERS (INBORN). PORPHYRIA
SEE ALSO VITAMIN B12
ROlHL-13412-17 Synthetic oxygen carriers
R01HL44508 10 Structure and lunction of respiratory
hemoprotems
ROlHL-14799-07 Cardiac heterotransplantation -
Immunologic modification (mice, rat)
ROlHL-1510407 A mechanism lor oxidative
phosphorylation
R01HL1562706 Xray and chemical studies ol
metalloporphyrins
R01HL15980-06 Reactions of hcmeproteins and oxygen
(cattle)
ROlHL-16087-05 Structural and dynamic study of model
heme complexes (yeast)
ROlHL-16093-05 Functional properties of hemoglobin and
erythrocytes
ROlHL-1686005 Mossbauer studies of respiratory
hemoproteins
ROlHL-17794-03 Chelating agents as blood substitutes
ROlHL-21461-01 Heme group protein interactions In
hemoproteins
ROlHL-22252-01 Synthesis ol labeled hemes for protein
NMR studies
PORPHYRINS, METALLOPORPHYRINS
** ROIHL 13157-09 Molecular oxygen carriers -Synthesis.
structure, bonding
** ROlHL-13651-07 X-ray photoeledron spectroscopy of heme
compounds
R01HL-14508-10 Structure and function of respiratory
hemoproteins
** ROlHL-1562706 X-ray and chemical studies of
metalloporphyrins
POlHL-16833-04 0015 Hemoglobin and red cell system in
hemoglobinopathies - Stereochemistry of hemoglobins from
magnetic circular dichroism (human)
ROlHL-21461-01 Heme group protein interactions in
hemoproteins
ROlHL-22252-01 Synthesis of labeled hemes for protein
NMR studies
PORPHYRINS STRUCTURE
ROlHL-13651-07 X-ray photoeledron spectroscopy of heme
compounds
PORPHYROPROTEINS, COBOGLOBINS
ROlHL-13531-06 Coboglobins -Cobalt substituted myo- and
hemoglobins
PORPHYROPROTEINS,
METALLOPORPHYROPROTEINS
SEE ALSO HEMOPROTEINS
SEE ALSO PORPHYROPROTEINS. COBOGLOBINS
** ROlHL-16087-05 Structural and dynamic study of model
heme complexes (yeast)
ROlHL-18226-04 Mechanism of oxygen supply to tissue
(human, animals)
PORTACAVAL SHUNT
SEE LIVER CIRCULATION. VENOUS BYPASS OF LIVER
PORTAL HYPERTENSION
SEE LIVER CIRCULATORY DISORDERS. PORTAL
HYPERTENSION
PORTAL SHUNTS
SEE LIVER CIRCULATION. VENOUS BYPASS OF LIVER
PORTAL VEIN
SEE LIVER CIRCULATION. PORTAL VEIN
429
PORTOSYSTEMIC SHUNTS
SfF lIVfR CIRCUIAIION VINOUS BYPASS OF LIVER
POSITIVE PRESSURE BREATHING
SEE RESPIRAIORY ASSIST AND OXYGEN AOMINISTRAnON.
POSIIIVF PRESSURE BREATHING
POSITRON AXIAL TOMOGRAPHY
SEE RADIOAUTOGRAPHY. RADIONUCLIDE SCANNING.
POSITRON AXIAl TOMOGRAPHY-
POSITRON CAMERAS
SEE RADIOASSAY, SCINTILLATION CAMfRAS, POSITRON'
POSITRON EMISSION TRANSAXIAL
TOMOGRAPHY
SEE RADIOAUTOGRAPHY, RADIONUCLIDE SCANNING,
POSITRON AXIAL TOMOGRAPHY-
POSITRON SCANNING
SEE RADIOAUTOGRAPHY, RADIONUCLIDE SCANNING,
POSITRON*
POSTEMBRYONIC ANIMAL LIFE STAGES
SEE AGE (ANIMAL), IMMATURE
POSTGRADUATE EDUCATION
SEE EDUCATION, POSTGRADUATE
POST-HOSPITALIZATION CARE
SEE HEALTH CARE SERVICES, PATIENT CARE, POST-
HOSPITALIZATION CARE
POST-MORTEM
SEE DEATH, POST MORTEM
POSTNATAL
SEE CHILDREN, INFANT NEWBORN (BIRTH TO 4-6 WKS)
POSTNATAL CARE
SEE HEALTH CARE SERVICES, MATERNAL AND INFANT CARE
POSTOPERATIVE
SEE SURGERY, POSTOPERATIVE
POSTOPERATIVE COMPLICATIONS
SEE DISEASES, COMPLICATIONS, POSTOPERATIVE
POSTPERICARDIOTOMY SYNDROME
SEE DISEASES, COMPLICATIONS, POSTPERICARDIOTOMY
SYNDROME
POSTURAL HYPOTENSION
SEE CARDIOVASCULAR DISORDERS, HYPOTENSION POSTURAL
POSTURE
SEE SKELETAL MOVEMENT, POSTURE
POTASSIUM
SEE ALSO BODY FLUID BALANCE. IONIC. HYPERKALEMIA
SEE ALSO BODY FLUID BALANCE. IONIC. HYPOKALEMIA
SEE ALSO RADIOISOTOPES. POTASSIUM
ROlHL-02493-22 Kidney function in experimental heart
failure (dogs, rats)
ROlHL-02888-22 Interrelationships of circulation and
respiration (opossum, cats)
ROlHL-03303-21 Fadors regulating electrolyte excretion by
the kidney (human, dogs)
R01HL05883-18 0003 Reflex control of resistance and
capacitance vessels - Cardiac glycosides and sympathetic
nerve terminals in vascular smooth muscle
R01HL-06I43-18 Response of the tdally denervated heart
to exercise (dogs)
POlHL-06285-18 0194 Cardiovascular-respiratory
physiology and biochemistry - Hormonal regulation of
sodium transport-RNA synthesis (rats, toads)
POlHL-06285-18 0195 Cardiovascular-respiratory
physiology and biochemistry - Thyroid thermogenesis and
sodium transport (rats)
P01HL06285-18 0197 Cardiovascular-respiratory
physiology and biochemistry - Micropertusion and
micropuncture of renal tubules (hamsters, desert rats)
POlHL-063 12-17 0051 Surgical cardiology - Diuretic
therapy on myocardial electrolyte composition and water
content (human)
PGlHL-07896-15 0049 Environmental biomedical research
program - Effects of hyperbaric oxygen and pressure on
cerebral enzymes (rats)
P0IHL08682-15 0037 Regulation of the cardiovascular
system - Central nervous regulation of cardiopulmonary
mechanisms (cats)
ROlHL-09364-14 Ion transport by heart mitochondria
(cattle, rat, rabbit)
ROlHL-10503-13 Cardiac ion transport and ultrastrudure
(rats, guinea pigs, rabbits)
R01HL106 12-13 0021 Humoral ladors in heart failure
and hypertension The control of aldosterone secretion
(dogs)
POlHL-1 13 10-12 0063 Mechanisms ol cardiovascular
disease - Myocardial lundion, metabolism and cellular
integrity after heart surgery (dogs)
POlHL-11351-12 0018 Cellular and molecular
mechanisms of myocardial function - Quantitative
localization of electrolytes in cardiac tissue
P01HH1678-11 0040 Cardiovascular dynamics and their
control - Control of plasma potassium concentration (dogs)
POT
POIHI llb/H II 004() Caidiova-.rulai ilyn '"-ir
control Regulation of aldo-.lerone lecreliuri i i ■ • :
factors (dogs)
POIHI 116/8 II 0063 Cardiovajcular dynamic* and Ihtir
control Renin angiotensin system Control ol renal
hemodynamics, electrolyte excretion
POIHI 1215/ 11 0033 functions and mechanisms ol tell
membrane ion transport Immunology aspects ol active
Na K transport in sheep red cell (also human, mice)
POIHL 1215/ II 0060 Functions and mechanisms ol cell
membrane ion transport Ion transport and electrical
properties ol giant celled aiga
ROIHL 12/92 09 Local control of the microcirculation
(hamsters, rats)
ROIHI 13193 09 Pathophysiology ol post traumatic and
shock states (rodents, dogs)
ROIHL 13237 09 Erythrocytes during early development
(human, animals)
ROIHL 13339-08 Pharmacology ol developing cardiac
tissues (chick embryo)
ROIHL 13349 06 Analysis ol activation process in heart
muscle (guinea pigs, rabbits, human)
ROlHL-13841 16 Respiration during altitude
acclimatization (goats, dogs, rats, rabbits)
ROIHL 14020 06 Characterization ol myosin Irom blood
platelets (rabbit)
* POIHL 1438807 0151 Regulation of the circulation in
pathological states Catecholamine release in potassium
ion free contractures in the caudal artery
* POIHL 14388 07 0152 Regulation of the circulation in
pathological states Ion flux alterations in caudal artery in
SHR
POIHL 1438807 0154 Regulation ol the circulation in
pathological states Energetics of smooth muscle
contraction (rats)
POIHL 1438807 0190 Regulation of the circulation in
pathological states Mechanisms ol the renal actions of
aldosterone (rats)
POlHL-14414 07 0014 Environmental influences on
cardiorespiratory and cellular functions Temperature and
acidbase status in tissues, cells, and subcellular system
ROlHL-14644-05 Optimization diastolic augmentation and
systolic sink (dogs)
ROlHL-14899-07 Mechanism and prevention of cardiac
arrhythmias (dogs)
ROlHL-15813 05 Cardiac anoxia -Protedive effect of
carbohydrate (dogs)
ROIHL- 16 746-04 Design of lonseleclive molecules
ROlHL-16760-05 Dynamic control of coronary blood How
(dogs)
P01HL16833-04 0008 Hemoglobin and red cell system in
hemoglobinopathies - Membrane associated phenomena in
SS disease
ROlHL-1745105 Digitalis effects on cardiac automaticity
mechanisms
P50HL-17646-04 0014 Study ol ischemic heart disease
Progression ol ischemic in|ury in conscious dogs (also
rabbits)
ROlHL-17749-03 Adrenocortical factors in human
hypertension (human)
R01HL17879-04 Molecular structure ol the ouabain
sensitive ATPasc (dogs)
ROlHL-17932-04 Blood flow regulation in muscle (cats)
R01HL18053-03 Intracellular ionic activities in heart
muscle (frogs)
ROlHL-18185-04 Cardiac glycosides and diuretics -Role of
NaO pump (dogs)
P50HL18323-04 0011 SCOR hypertension center -
Endocrine profiling on a selected normal population
(human)
ROlHL-18351-03 Brain metabolism, acidbase balance,
and respiration
ROlHL-18537-04 Regional blood flow atter acute
myocardial injury (dogs)
POlHL-18575-03 0002 Mechanisms of vascular changes
in hypertension • Endocrines, electrolytes, and
hemodynamics in hypertension (pigs)
" ROlHL-18798-04 0001 Nervous and ionic factors in
sudden cardiac death - Potassium loss during myocardial
ischemia (rabbits)
ROlHL-18798-04 0002 Nervous and ionic factors in
sudden cardiac death - Electron microprobe, ultrastrudure
analysis of ischemic myocardium (dog. rabbit)
ROlHL-18882-02 Hormones in hypertension (human)
** R01HL18891-02 Electrolyte intake and blood pressure in
hypertension (human)
ROlHL-1903003 Tissue protection during circulatory
interruption (dogs)
ROlHL-1939803 Regional conduction abnormalities and
arrhythmias (dogs)
ROlHL-19467-03 Regulation of blood pressure (rats, dogs)
ROlHL-19673-03 Surgical aspects of shock and hypoxia
(dogs, monkeys, rats)
R01HL19674-02 Electrolyte permeability of single
capillaries (frogs)
ROIHL 20558-02 Cardiac electrophysiulogy -Effects of ions
and drugs
POlHL-20592-02 0003 Cell biology of cardiac and
skeletal muscle - Cellular magnesium and anion activities
in ion-specific microeledrodes (frogs)
(contd)
•Excludes routine methodology OR covers only general projects which preclude
"Onented significantly to above subject.
indexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
POT
POlHL-20592-02 0013 Cell biology of cardiac and
skeletal muscle • Sarcoplasmic reticulum in skinned
muscle cells (frogs)
R01HL-20711OI Structure-function relationships in red
cell NA-K pumps (goats)
R01HL-20720-02 Myocardial protection during
cardiopulmonary bypass (dogs)
ROlHL-20725-02 Mechanisms and cellular functions of ion
transport
ROlHL-20910-02 The alternative diet for coronary disease
prevention (human)
ROlHL-21030-01 Calcium regulation and hypertension
(rats)
ROlHL-2 114502 Response of atria to hyperosmolality--
Mechanisms (rabbits)
R01HL21187-01 Potassium, norepinephrine, and coronary
arterial tone (dogs)
R23HL2119602 Digitalis induced arrhythmia and NAO KO-
atpase activity (dogs)
ROlHL-21371-02 Energy loss microanalysis of myocardial
cations
R23HL-2 1434-02 Intrinsic control of coronary blood flow by
chemicals (guinea pigs)
ROIHL 21435-02 Control, cardiovascular and renal effects
of potassium (dogs)
ROIHL 21493-02 Contractility in cardiac failure (hamsters)
ROlHL-21523 01 Hemodynamic effects of dietary sodium
in man
ROlHL-21673-01 Pathophysiology of venous changes in
hypertension (rats, rabbits, human, dogs)
ROlHL-22039-02 Ion transport in cardiac muscle (dogs,
rodents, cattle)
ROlHL-22088-02 Metabolic basis for diabetic
microangiopathy (cattle)
ROIHL 22426-01 Initiation of the heartbeat -A voltage-
clamp study (bullfrogs, rabbits)
R23HL 22975-01 Dynamics of autoregulation of muscle
blood flow (dogs)
ROlHL-23392-01 Membrane binding and transport of
calcium and potassium ionophores
POTASSIUM CHLORIDE
POlHL-14388-07 0178 Regulation of the circulation In
pathological states - Structural and functional
consequences of denervation (rats)
P50HL-1 7667-04 0040 Study of ischemic heart disease -
Core biochemistry-Cardiac metabolism (human)
POTASSIUM LOSING KIDNEY DISEASE
(BARTTER'S SYNDROME)
SEE METABOLIC DISORDERS INBORN, BARTTER'S SYNDROME
POTASSIUM PUMP
SEE BIOLOGICAL TRANSPORT, ACTIVE TRANSPORT, fON
PUMPS, POTASSIUM PUMP
POTASSIUM RADIOISOTOPES (38,40,42,43)
SEE RADIOISOTOPES, POTASSIUM
POTENTIALS
SEE ELECTROPOTENTIALS
POTENTIATION
SEE DRUGS AND PHYSICAL AND/OR CHEMICAL AGENTS
INTERACTION
SEE DRUGS INTERACTION
SEE PHYSICAL AND/OR CHEMICAL AGENTS INTERACTION
(BIOLOGICAL AND ECOLOGICAL)
POTENTIOMETRY
SEE ELECTRICAL MEASUREMENTS, POTENTIOMETRY*
POWDERS (DOSAGE FORM)
SEE DOSAGE FORMS
PPLO
SEE BACTERIA, MYCOPUSMATALES. MYCOPLASMA*
SEE RESPIRATORY DISORDERS. PNEUMONIA MYCOPUSMAL
(PPLO)
PRACTOIOL
SEE PHENYLAMIOES, PRACTOLOL
PRAUSNITZ-KUSTNER REACTION
SEE HYPERSENSITIVITY, SKIN SENSITIZING ANTIBODY
PRE-BETA LIPOPROTEINS
SEE LIPOPROTEINS BLOOD, VLDL
PREBIOTIC EVOLUTION
SEE BIOLOGY, SYSTEMATIC, EVOLUTION BIOCHEMICAL
PRECIPITATION
SEE PHYSICAL PROPERTIES, PRECIPITATION
PREDIABETIC STATE
SEE CARBOHYDRATES METABOLISM DISORDERS, DIABETES
PREDIABETIC STATE
PREDICTION OF BEHAVIOR
SEE PSYCHOLOGY, BEHAVIOR PREDICTION
PREDICTION OF DISEASE OUTCOME
SEE DISEASES, PROGNOSIS
PREDISPOSITION TO DISEASE
SEE DISEASE PRONENESS-RISK
430
PREDNISONE
SEE ADRENAL CORTEX HORMONES ANALOGS, PREDNISONE
PREGANGLIONIC FIBERS
SEE NERVOUS SYSTEM. GANGLIA. PREGANGLIONIC FIBERS
PREGNANCY
SEE ALSO CONGENITAL ABNORMALITIES
SEE ALSO EMBRYOLOGY
SEE ALSO EMBRYOLOGY (HUMAN) AND DEVELOPMENT STUDY
SECTION
SEE ALSO FAMILY PLANNING
SEE ALSO FERTILITY
SEE ALSO HEALTH CARE SERVICES. MATERNAL AND INFANT
CARE
SEE ALSO NUTRITION, MATERNAL-FETAL NUTRITION
*• ROlHL-03941-18 Uterine blood flow and changes m
pregnancy (sheep)
POlHL-06835-17 0034 Cardiovascular disease - Studies
of phospholipase A2 in serum (rats, dogs)
ROlHL-10612-13 0020 Humoral factors in heart failure
and hypertension - The control of renin release in the dog
** ROlHL-12557-09 Effects of steroids and pregnancy on
arteries and veins (guinea pigs)
ROlHL-13901-08 Ontogeny, ultrastructure, function in
lymphatic system (birds, fish, mammals)
*• POlHL-14985-07 0015 Adaptation to hypoxia - Pregnancy
at high altitude (human, animals)
ROlHL-16918-05 Role of steroids In hypertension (human)
ROlHL-17364-04 Big renin' -Biochemical and clinical
studies (human)
R01HL-19859-03 Epidemiological studies, precursors of
hypertension (human)
ROlHL-20922-02
synthesis
Control of human fetal hemoglobin
Regulation of fetal hemoglobin in
Biosynthesis of lung surfactant lipid
ROlHL-20939-02
humans
ROlHL-21628-02
(rabbit)
R01HL-22225-01 Hormonal regulation of blood pressure
and blood flow (human, animals)
R01HL-22258-01 New aspects of pharmacology related to
carbonic anhydrase
NOlHV-12157-14 Lipid research clinic (human)
PREGNANCY, AMNIOCENTESIS
P50HL-19185-02 0006 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Evaluation of risk factors
in neonatal respiratory distress (human, sheep)
P50HL-19187-02 0002 Pediatric pulmonary SCOR -Hyaline
membrane disease - Hyaline membrane disease-Alterations
in surface active material (monkeys)
ROlHL-20070-02 Alpha-1-antitrypsin deficiency (human,
hamsters)
PREGNANCY, ANTEPARTUM DIAGNOSIS
SEE ALSO PREGNANCY, AMNIOCENTESIS
POlHL-06285-18 0125 Cardiovascular-respiratory
physiology and biochemistry - Myocardial function in the
fetal and neonatal lamb
POlHL-06285-18 0128 Cardiovascular-respiratory
physiology and biochemistry - Pulmonary circulation in fetal
lambs in utero
POlHL-06285-18 0129 Cardiovascular-respiratory
physiology and biochemistry - Pulmonary microcirculation in
the fetus and neonate (lambs)
POlHL-06285-18 0130 Cardiovascular-respiratory
physiology and biochemistry - Ductus arteriosus -
Morphological development (human, lambs)
POlHL-06285-18 0131 Cardiovascular-respiratory
physiology and biochemistry - Fetal heart development and
ventricular outflow obstruction (lambs)
POlHL-06285-18 0132 Cardiovascular-respiratory
physiology and biochemistry - Umbilical-placental
circulatory responses (lambs)
POIHL-06285-18 0133 Cardiovascular-respiratoiy
physiology and biochemistry - Decreased uterine blood flow
and fetal development (lambs)
POlHL-06285-18 0134 Cardiovascular-respiratoiy
physiology and biochemistry - Placental transfer in growth
retarded fetuses (lambs)
POlHL-06285-18 0135 Cardiovascular-respiratory
physiology and biochemistry - Beta-adrenergic agents and
fetal cardiovascular dynamics (lambs)
POlHL-06285-18 0136 Cardiovascular-respiratory
physiology and biochemistry - Fetal microcirculation In
utero (rabbits, lambs)
** P50HL-142 18-07 0014 Pulmonary SCOR-Newborn lung
center - Longitudinal study of ROS -Monitoring fetal
breathing movements (human)
POlHL-14388-07 0188 Regulation of the circulation in
pathological states - Renin-angiotensin system in the sheep
fetus
** ROlHL-19646-03 An immunologic study of hemoglobin
variation in man
ROlHL-20070-02 Alpha-1-antitrypsin deficiency (human,
hamsters)
•* P60HL-20985-01 0010 Northern California sickle cell
center - Prenatal diagnosis of sickle cell anemia
ROlHL-21756-11 Vascular disease-Cytochemistry and
ultrastructure (human, rats, mice, hamsters)
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level
Onemed significantly to above subject
M Grant has subprojects describing specific research aspects
See Appendix for investigator's name and grant number.
PRE
** P60HL-23282-01 0001 Comprehensive hospital/community
sickle cell center - Fetoscopy for intrauterine diagnosis of
hemoglobinopathy (human, monkeys)
NOlHR-72922-01 Cystic fribrosis factor identication and
quantification (human)
PREGNANCY, BIRTH
SEE ALSO AGE (ANIMAL), INFANTS, BIRTH WEIGHT
SEE ALSO PREGNANCY DISORDERS. UBOR COMPLICATIONS
P50HL-142 14-07 0029 Newborn lung center for hyaline
membrane disease - The diving reflex -Perinatal asphyxia,
pulmonary ischemia and HMD (sheep)
P50HL-14218-07 0012 Pulmonary SCOR-Newborn lung
center - Longitudinal study of RDS -On-line fetal and
neonatal monitoring (human)
** P50HL- 142 18-07 0013 Pulmonary SCOR-Newborn lung
center - Longitudinal study of RDS -Monitoring fetal P02
and PC02 during labor (human)
PREGNANCY, EMBRYO-FETUS
SEE ALSO CARDIOVASCULAR SYSTEM. DUCTUS ARTERIOSUS
EMBRYONIC
SEE ALSO ENZYMES, FETAL ENZYMES
SEE ALSO HEART, FORAMEN OVALE EMBRYONIC
ROlHL-01755-25 Fetal and neonatal cardiovascular
function (sheep)
R01HL01803-23 0018 Arteriosclerosis, glomerulonephritis.
rheumatic fever - Fetal immunization in pathogenesis of
glomerulonephritis in adult (rabbit)
ROlHL-01803-23 0019 Arteriosclerosis, glomerulonephritis.
rheumatic fever - Pathogenesis of rheumatic heart disease
(rabbit)
ROlHL-03357-21 Humoral control of blood cell formation
and release (rats, mice)
** POlHL-06285-18 0125 Cardiovascular-respiratory
physiology and biochemistry - Myocardial function in the
fetal and neonatal lamb
" POlHL-06285-18 0126 Cardiovascular-respiratory
physiology and biochemistry - Ventricular output, foramen
ovale and ductus arteriosus flows (lambs)
•* POlHL-06285-18 0127 Cardiovascular-respiratoiy
physiology and biochemistry - Experimental congenital
cardiac lesions in fetal lambs
'* POlHL-06285 18 0128 Cardiovascular-respiratory
physiology and biochemistry - Pulmonary circulation in fetal
lambs in utero
•* POlHL-06285-18 0129 Cardiovascular-respiratoiy
physiology and biochemistry - Pulmonary microcirculation in
the fetus and neonate (lambs)
■* POlHL-06285-18 0130 Cardiovascular-respiratory
physiology and biochemistry ■ Ductus arteriosus-
Morphological development (human, lambs)
* POlHL-06285-18 0131 Cardiovascular-respiratory
physiology and biochemistry - Fetal heart development and
ventricular outflow obstruction (lambs)
* POlHL-06285-18 0132 Cardiovascular-respiratory
physiology and biochemistry - Umbilical-placental
circulatory responses (lambs)
* P01HL06285-18 0136 Cardiovascular-respiratory
physiology and biochemistry - Fetal microcirculation in
utero (rabbits, lambs)
ROlHL-10834-09 Fetal and neonatal pulmonary circulation
(goats)
POlHL-11310-12 0097 Mechanisms of cardiovascular
disease - Structural-functional relationships of neuronal
differential alloantigens (mice)
POlHL-12157-11 0057 Functions and mechanisms of cell
membrane ion transport - Electrophysiological
investigations of synthetic strands of heart muscles (rats)
POlHL-12373-10 0005 Cardiopulmonary physiology and
pathophysiology - Characterization of fetal and neonatal
myocardium (human, cats)
ROlHL-13339-08 Pharmacology of developing cardiac
tissues (chick embryo)
R01HL-13634-08 Renal hypertension in pregnancy (sheep)
ROlHL-13901-08 Ontogeny, ultrastructure. function in
lymphatic system (birds, fish, mammals)
P50HL-14141-05 0002 SCOR for atherosclerosis in
childhood - Intrauterine environment of proband group
(human)
P50HL-14214-07 0015 Newborn lung center for hyaline
membrane disease - Hormone effect on cyclic nucleotide
lipid synthesis in developing lung (animal)
P50HL-14214-07 0020 Newborn lung center for hyaline
membrane disease - Epidermal growth factor effect -Lung
differentiation, maturation (human, rabbit)
P50HL-14214-07 0021 Newborn lung center for hyaline
membrane disease - Development of surfactant system-
Surfactant production and release (rat, rabbit)
P50HL-14214-07 0022 Newborn lung center for hyaline
membrane disease - Functional integrity of surfactant
system-Hyaline membrane disease (lamb, rat)
P50HL-14214-07 0029 Newborn lung center for hyaline
membrane disease - The diving reflex-Perinatal asphyxia.
pulmonary ischemia and HMD (sheep)
P50HL-14214-07 0035 Newborn lung center for hyaline
membrane disease - Core-Animal care facility
P50HL-14218-07 0012 Pulmonary SCOR-Newborn lung
center - Longitudinal study of RDS -On-line fetal and
neonatal monitoring (human)
P50HL-14218-07 0013 Pulmonary SCOR-Newborn lung
center - Longitudinal study of RDS -Monitoring fetal P02
and PC02 during labor (human)
(contd)
P50HL 1421807 0014 Pulmonary SCOR Newborn lung
center Longitudinal study ol ROS Monitoring l«tal
breattiing movements (human)
POIHL 143880/ 0188 Regulation ol the circulation in
pathological stales Renin angiotensin system in the sheep
tetus
ROIHL 15341 06 Lung hormonal and chromosomal
regulation (rats, rabbits)
POIHL 16137 05 0001 Alveolar biology Chemical
characteniation ol surlactant system Lipid and lipid
protein tractions
POIHL 16137 05 0008 Alveolar biology Macromolecular
events in pulmonary cells in toxic environments (animals)
POIHL 16137 05 0013 Alveolar biology Development and
pathology ot surlactant Formation ol alveolar (rabbits,
sheep)
ROIHL 1644505 Regulation ol plasma protein
biosynthesis (rats, rabbits)
POIHL 174 1904 0003 Studies on mechanisms of
hemostasis Characterization of fibrinogen (human)
P50HL 17682 04 0018 Study of ischemic heart disease
Biochemistry of ischemia-Heart cell and organ culture
(mice, rats, cattle)
P50HL 1768204 0023 Study of ischemic heart disease •
Core cell and organ culture laboratory (mice)
POIHL 17731-04 0003 Physiological basis of pulmonary
disease Comparative physiology (vertebrates)
* ROlHL-18952-03 Metabolism in perfused fetal and
newborn rabbit lungs
ROIHL 19010-03 Metabolism and cell biology of lung
surfactant system (rabbits, sheep)
P50HL-19185-02 0001 Pulmonary SCOR -Neonatal
respiratory distress syndromes Sites of synthesis.
secretion and structure of surface active material (rat)
P50HL-19185-02 0002 Pulmonary SCOR -Neonatal
respiratory distress syndromes Biochemistry,
ultrastructure -Pulmonary surface active material (human,
animal)
P50HL-19185-02 0004 Pulmonary SCOR -Neonatal
respiratory distress syndromes - Fluid and protein transport
in fetal and newborn lung (sheep, rabbits)
P50HL-19190-02 0007 Pulmonary SCOR -Pathophysiology,
management of IRDS Asphyxia -Cerebral metabolism (dog,
rat)
ROlHL-19684-03 Histotypic lung culture in circumfusion
systems (mice)
'* ROlHL-19752-03 Phospholipid synthesis by fetal lung in
organ culture (rats)
ROlHL-20337-02 Thromboembolic diseases (human)
ROlHL-20548-02 Innervation of the lung (rats, monkeys)
ROlHL-20635-03 Factors in lung development (rat and
chick embryo)
ROlHL-20899-02 Cellular mechanisms of hemoglobin F
regulation (human)
ROlHL-20961-02 Hemoglobin Y-chain genes -Evolution and
inducibility (monkeys, human)
ROlHL-21176-02 Phospholipid exchange proteins in lung
tissue (lambs)
R23HL-21368-02
R23HL-2 1409-02
(sheep)
ROlHL-21628-02
(rabbit)
ROlHL-22664-01
Perinatal cardiac electrophysiology (dogs)
Perinatal control of the ductus arteriosus
Biosynthesis of lung surfactant lipid
Regulation of myocardial cell growth
(rats, guinea pigs)
** R23HL-22775-01 Muscarinic receptors in the developing
heart (chick embryo)
P60HL-23282-01 0001 Comprehensive hospital/community
sickle cell center - Fetoscopy for intrauterine diagnosis of
hemoglobinopathy (human, monkeys)
ROlHL-23736-04 Sickle cell anemia and hemoglobin
synthesis (monkeys)
PREGNANCY, EMBRYO-FETUS, GESTATIONAL
AGE
POlHL-06285-18 0125 Cardiovascular-respiratory
physiology and biochemistry - Myocardial function in the
fetal and neonatal lamb
** POlHL-06285-18 0133 Cardiovascular-respiratory
physiology and biochemistry - Decreased uterine blood flow
and fetal development (lambs)
P50HL-14214-07 0023 Newborn lung center for hyaline
membrane disease - Regulation of fetal lung maturation-
Vitamin A (rat. rabbit, sheep, human)
P60HL-1 5999-05 0019 Miami comprehensive sickle cell
center - Fetal-adult hemoglobin switch (mouse, monkey)
P50HL19185-02 0003 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Factors affecting formation
and release of pulmonary surfactant in fetal lambs
ROlHL-19352-03 Respiratory heat and water loss in
neonates
ROlHL-20337-02
ROlHL-20632-02
ROlHL-20961-02
Thromboembolic diseases (human)
An optimal fetal heart monitor (human)
Hemoglobin Y-chain genes-Evolution and
inducibility (monkeys, human)
R23HL-2 1409-02 Perinatal control of the ductus arteriosus
(sheep)
PREGNANCY, EMBRYO-FETUS CHEMOTHERAPY
ROIHL- 148 54-0 7 Lung and tissue mechanics (monkeys,
dogs)
43)
P50HL 19185 02 0005 Pulmonary SCOR Neonatal
respiratory distress syndromes Role and mechanism o(
glucocorticoids in fetal lung maturation (human, rabbit)
*• NOIHR 62948 04 Evaluate antenatal steroid therapy in
neonatal respiratory distress syndrome
** NOIHR 62949 05 Evaluate antenatal steroid therapy in
neonatal respiratory distress syndrome
•* NOIHR 6295004 Evaluate antenatal steroid therapy in
neonatal respiratory distress syndrome
*• NOIHR 62951 04 Evaluate antenatal steroid therapy in
neonatal respiratory distress syndrome
" N01HR-6295205 Evaluate antenatal steroid therapy in
neonatal respiratory distress syndrome
PREGNANCY, EMBRYO-FETUS DRUGS ADVERSE
EFFECTS
SEE ALSO CONGENITAL ABNORMALITIES, TERATOGENIC
AGENTS
P50HL 1421807 0006 Pulmonary SCOR -Newborn lung
center Biochemical characteristics of the lung in RDS
(human, sheep)
** R23HL-21368-02 Perinatal cardiac electrophysiology (dogs)
PREGNANCY, EMBRYO-FETUS PHARMACOLOGY
SEE ALSO PREGNANCY. EMBRYO FETUS CHEMOTHERAPY
SEE ALSO PREGNANCY, EMBRYO FETUS DRUGS ADVERSE
EFFECTS
POIHL 10436-13 0015 A multidisciplinary study of
congenital heart disease Fetal and neonatal
cardiovascular physiology (sheep)
P50HL 14214-07 0020 Newborn lung center for hyaline
membrane disease Epidermal growth factor effect -Lung
differentiation, maturation (human, rabbit)
P50HL 14214-07 0023 Newborn lung center for hyaline
membrane disease Regulation of fetal lung maturation -
Vitamin A (rat, rabbit, sheep, human)
P50HL 1421407 0024 Newborn lung center for hyaline
membrane disease - Synthesis and receptors for ACTH In
fetal lung (human)
P50HL 14214-07 0026
membrane disease
Cellular and molecular aspects of
Cortisol-dependent alterations in
Newborn lung center for hyaline
- Hemodynamic studies of HMD-
Prostaglandins production and blockers (lambs)
P50HL 19187-02 0002 Pediatric pulmonary SCOR-Hyaline
membrane disease - Hyaline membrane disease-Alterations
in surface active material (monkeys)
P50HL-19 190-02 0007 Pulmonary SCOR -Pathophysiology.
management of IRDS Asphyxia -Cerebral metabolism (dog.
rat)
POIHL 19737-02 0003
respiratory physiology
lung type II cells (rats)
ROlHL-19752-03 Phospholipid synthesis by fetal lung in
organ culture (rats)
PREGNANCY, EMBRYO-FETUS SURGERY
POlHL-1043613 0015 A multidisciplinary study of
congenital heart disease - Fetal and neonatal
cardiovascular physiology (sheep)
PREGNANCY, EMBRYO-FETUS
TRANSPLANTATION
ROlHL-18191-04 Models of hypoxic pulmonaiy
hypertension (cattle, minipigs)
ROIHL 20905-02 Synthesis of fetal hemoglobin in erythroid
cells (sheep, human)
PREGNANCY, PERINATAL
SEE ALSO REPRODUCTIVE SYSTEM FEMALE. MAMMARY
GLANDS. LACTATION
** NOlHB-62908-07 Maternal to infant transmission of
hepatitis B (human)
P50HL 14214-07 0023 Newborn lung center for hyaline
membrane disease - Regulation of fetal lung maturation-
Vitamin A (rat. rabbit, sheep, human)
P50HL-142 14-07 0029 Newborn lung center for hyaline
membrane disease - The diving reflex-Perinatal asphyxia.
pulmonary ischemia and HMD (sheep)
P50HL-142 18-07 0012 Pulmonary SCOR -Newborn lung
center - Longitudinal study of RDS -On-line fetal and
neonatal monitoring (human)
POlHL-14388-07 0196 Regulation of the circulation in
pathological states ■ Altered vascular responsiveness in
spontaneous hypertension (rats)
POlHL-14388-07 0197 Regulation of the circulation in
pathological states • Altered vascular reactivity in
pathogenesis of spontaneous hypertension (rats)
P60HL-16005-05 0021 Comprehensive sickle cell center -
Management of pregnancy in sickle cell anemia (human)
P50HL-19185-02 0006 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Evaluation of risk factors
in neonatal respiratory distress (human, sheep)
** R23HL-21368-02 Perinatal cardiac electrophysiology (dogs)
ROlHL-22327-01 Transport of arterial blood gases through
skin (swine)
PREGNANCY, PLACENTA
P50HL 14214-07 0020 Newborn lung center for hyaline
membrane disease - Epidermal growth factor effect -Lung
differentiation, maturation (human, rabbit)
" P50HL-142 14-07 0024 Newborn lung center for hyaline
membrane disease - Synthesis and receptors for ACTH in
fetal lung (human)
PRE
P60HL 23282 01 0001 Comprehenilvt hojpital/community
ilckle cell center Fetojcopy lor intrauterine diagnom of
hemoglobinopathy (human, monkeys)
PREGNANCY, PLACENTAL NEOPLASMS,
HYOATIDIFORM MOLE
ROIHI 209390? Regulation of lelal hemoglobin in
humans
PREGNANCY, PRENATAL STRESS
SEE ALSO PREGNANCY. EMBRYO FETUS DRUGS ADVERSE
EFFECTS
R01H10175525 Fetal and neonatal cardiovascular
function (sheep)
POIHL 12373 10 0005 Cardiopulmonary physiology and
pathophysiology Characterization of fetal and neonatal
myocardium (human, cats)
P50HL 14141 05 0001 SCOR for atherosclerosis in
childhood Clinical implications (infants and children)
*• P50HL1414105 0002 ''.COR (yi alherosclerosr. in
childhood - Intrauterine environment of proband group
(human)
P50HL 14214 07 0026 Newborn lung center for hyaline
membrane disease Hemodynamic studies of HMO
Prostaglandins production and blockers (lambs)
P50HL-14218-07 0006 Pulmonary SCOR Newborn lung
center • Biochemical characteristics of the lung in RDS
(human, sheep)
P50HL 1421807 0012 Pulmonary SCOR Newborn lung
center Longitudinal study of RDS On line fetal and
neonatal monitoring (human)
P50HL19190 02 0007 Pulmonary SCOR- Pathophysiology,
management of IRDS Asphyxia -Cerebral metabolism (dog.
rat)
ROIHL 19864-03 0003 Blood pressure of children and
young adults Heart rale and blood pressure -Consistency
in infancy (human)
PREGNANCY, UMBILICAL CORD
POlHL-06285 18 0132 Cardiovascular respiratory
physiology and biochemistry - Urabilical-placental
circulatory responses (lambs)
ROlHL-15308-07 Assays for peptides of lipoproteins
(human)
PREGNANCY CIRCULATION
ROlHL-01755-25 Fetal and neonatal cardiovascular
function (sheep)
" POlHL-10436-13 0015 A multidisciplinary study of
congenital heart disease Fetal and neonatal
cardiovascular physiology (sheep)
P50HL-14141-05 0002 SCOR for atherosclerosis in
childhood ■ Intrauterine environment of proband group
(human)
P60HL-23282-01 0001 Comprehensive hospital/community
sickle cell center - Fetoscopy for intrauterine diagnosis of
hemoglobinopathy (human, monkeys)
PREGNANCY CIRCULATION, PLACENTAL
TRANSFER
SEE ALSO PREGNANCY IMMUNOLOGY
** ROlHL-01803-23 0018 Arteriosclerosis, glomerulonephritis,
rheumatic fever Fetal immunization in pathogenesis of
glomerulonephritis in adult (rabbit)
ROlHL-01803-23 0019 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Pathogenesis of rheumatic heart disease
(rabbit)
** POlHL-06285-18 0132 Cardiovascular respiratory
physiology and biochemistry - Umbiiical-placental
circulatory responses (lambs)
** POlHL-06285-18 0134 Cardiovascular-respiratory
physiology and biochemistry - Placental transfer in growth
retarded fetuses (lambs)
" P01HL06285-18 0135 Cardiovascular-respiratory
physiology and biochemistry - Beta-adrenergic agents and
fetal cardiovascular dynamics (lambs)
POlHL-09011-15 0020 A research and resource program
in blood - Passive immunization in the prevention of
transmission of hepatitis B (human)
POlHL-10342-13 0014 The integrated function of
respiration and circulation - Oxygen and carbon monxide
transfer (human, dogs, sheep)
ROlHL-12174-11 Ventilation/perfusion distribution in the
lung (human, mammals)
P01HL-12373-IO 0005 Cardiopulmonary physiology and
pathophysiology - Characterization of fetal and neonatal
myocardium (human, cats)
POlHL-12738-10 0108 Physiologic pharmacology and its
clinical applications - Developmental electrophysiology and
pharmacology (human, animals)
ROlHL-1363408 Renal hypertension in pregnancy (sheep)
P50HL-14214-07 0026 Newborn lung center for hyaline
membrane disease - Hemodynamic studies of HMD-
Prostaglandins production and blockers (lambs)
** ROlHL-15655-05 Blood flow and gas exchange in placenta
and lungs (sheep) rabbits)
ROlHL-1965103 Host factors in pathogenesis of
respiratory disease (human, hamsters)
PREGNANCY CIRCULATORY DISORDERS
SEE ALSO PREGNANCY TOXEMIAS AND HYPERTENSION
POlHL-06285-18 0132 Cardiovascular-respiratory
physiology and biochemistry - Umbiiical-placental
circulatory responses (lambs)
(contd)
•Excludes routine methodotogy OR covers only general projects which preclude
"Oriented significantly to above subject.
indexing at the specific level.
M Grant has subprajects describing specific research aspects.
See Appendix for investigator's name and grant number
PRE
** POlHL-06285-18 0133 Cardiovascular-respiratory
physiology and biochemistry ■ Decreased uterine blood flow
and fetal development (lambs)
P01HL06285-18 0134 Cardiovascular-respiratory
physiology and biochemistry - Placental transfer in growth
retarded fetuses (lambs)
POlHL-06285-18 0135 Cardiovascular-respiratory
physiology and biochemistry - Beta-adrenergic agents and
fetal cardiovascular dynamics (lambs)
PREGNANCY COMPLICATIONS
CARDIOVASCULAR
SEE PREGNANCY CIRCUUTORY DISORDERS
PREGNANCY DISORDERS
SEE ALSO CARBOHYDRATES METABOLISM DISORDERS,
DIABETES IN PREGNANCY
SEE ALSO PREGNANCY. EMBRYO-FETUS DRUGS ADVERSE
EFFECTS
SEE ALSO PREGNANCY TOXEMIAS AND HYPERTENSION
P50HL1414105 0002 SCOR for atherosclerosis m
childhood • Intrauterine environment of proband group
(human)
** P60HL 16005-05 0021 Comprehensive sickle cell center -
Management of pregnancy in sickle cell anemia (human)
PREGNANCY DISORDERS, EMBRYO-FETAL
DISORDERS (GENERAL)
SEE ALSO CONGENITAL ABNORMALITIES
ROIHL 01755-25 Fetal and neonatal cardiovascular
function (sheep)
** ROIHL 2296301 Symbolic logic analysis of congenital
heart disease (human)
PREGNANCY DISORDERS, EMBRYO-FETAL
GROWTH-DEVELOPMENT DISORDERS (SEE
ALSO APPROPRIATE SPECIFICS)
POlHL-0628518 0129 Cardiovascular-respiratory
physiology and biochemistry - Pulmonary microcirculation in
the fetus and neonate (lambs)
•* POlHL-06285-18 0133 Cardiovascular-respiratory
physiology and biochemistry ■ Decreased uterine blood flow
and fetal development (lambs)
** POlHL-06285 18 0134 Cardiovascular-respiratory
physiology and biochemistry - Placental transfer in growth
retarded fetuses (lambs)
POIHL-06285-18 0135 Cardiovascular-respiratory
physiology and biochemistry - Beta-adrenergic agents and
fetal cardiovascular dynamics (lambs)
POlHL-06285-18 0136 Cardiovascular-respiratory
physiology and biochemistry - Fetal microcirculation in
utero (rabbits, lambs)
** ROIHL 22859-01 Effect of carbon monoxide on the
developing heart (rats)
PREGNANCY DISORDERS, LABOR
COMPLICATIONS
P60HL16005-05 0021 Comprehensive sickle cell center -
Management of pregnancy in sickle cell anemia (human)
PREGNANCY DISORDERS, PROLONGED
PREGNANCY
P50HL 14214-07 0020 Newborn lung center for hyaline
membrane disease - Epidermal growth factor effect -Lung
differentiation, maturation (human, rabbit)
PREGNANCY DISORDERS CHEMOTHERAPY
ROlHL-22258-01 New aspects of pharmacology related to
carbonic anhydrase
PREGNANCY IMMUNOLOGY
** R01HL0I803-23 0018 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Fetal immunization in pathogenesis of
glomerulonephritis in adult (rabbit)
** ROlHL-01803-23 0019 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Pathogenesis of rheumatic heart disease
(rabbit)
R01HL01803-23 0021 Arteriosclerosis, glomerulonephritis,
rheumatic fever ■ Induction of IgE antibodies to antigen
from tobacco and cigarette smoke (rabbits)
ROIHL 19651-03 Host factors in pathogenesis of
respiratory disease (human, hamsters)
PREGNANCY LOSS, FETAL DEATH
P60HL-16005-05 0021 Comprehensive sickle cell center -
Management of pregnancy in sickle cell anemia (human)
ROlHL-19430-03 Congenital heart malformations and
situs inversus (mice)
PREGNANCY TOXEMIAS AND HYPERTENSION
** R0IHL13634-08 Renal hypertension in pregnancy (sheep)
P50HL-I414105 0002 SCOR for atherosclerosis in
childhood - Intrauterine environment of proband group
(human)
P50HL-14 159-08 0008 Specialized center of research in
hypertension - Renal function and sodium metabolism in
hypertension (rats, human, rabbits)
P50HL-14 159-08 0020 Specialized center of research in
hypertension - Reninmineralocorticoid system in
hypertension (human, rat, dog)
P50HL-14159-08 0024 Specialized center of research in
hypertension - Core resources (clinical, animal models)
432
P50HL142 18-07 0006 Pulmonary SCOR-Newborn lung
center - Biochemical characteristics of the lung in RDS
(human, sheep)
ROlHL-16603-05 Human and experimental renal diseases
(animals)
** ROlHL-1884504 Regulation of renal circulation and salt
excretion (rats, dogs)
ROlHL-19869-03 Antecedents of adolescent hypertension
(human)
ROlHL-19956-03 High blood pressure in the young
(human)
ROlHL-22225-01 Hormonal regulation of blood pressure
and blood flow (human, animals)
PREGNANCY TOXEMIAS AND HYPERTENSION,
ECLAMPSIA
R01HL1985803 UMMC -Blood pressure precursors and
consequences (human)
R01HL2360201 Physiology of renin, aldosterone and
prostaglandin (human, rats, dogs)
PREMATURE INFANT
SEE CHILDREN, INFANT PREMATURE AND LOW BIRTH WEIGHT
PREMATURE INFANT ANIMALS AND LOW BIRTH
WEIGHT
SEE AGE (ANIMAL), INFANTS PREMATURE AND LOW BIRTH
WEIGHT
PREMATURE VENTRICULAR CONTRACTIONS
SEE HEART DISORDERS, ARRHYTHMIA, PREMATURE
VENTRICULAR CONTRACTIONS
PRENATAL CARE
SEE HEALTH CARE SERVICES, MATERNAL AND INFANT CARE
PRENATAL INFLUENCE
SEE PREGNANCY, PRENATAL STRESS
PRENATAL STRESS
SEE PREGNANCY, PRENATAL STRESS
PREOPERATIVE
SEE SURGERY, PREOPERATIVE
PRESBYTIS
SEE MAMMALS, PRIMATES, MONKEYS AND APES
(ANTHROPOIDS, NON-HUMAN), OLD WORLD MONKEYS
(CATARRHINES)*
PRESCHOOL
SEE CHILDREN, PRESCHOOL (1 TO 6 YRS)
PRESERVATION
SEE BLOOD PRESERVATION
SEE CARDIOVASCULAR TISSUE PRESERVATION
SEE HEART PRESERVATION
SEE KIDNEY PRESERVATION
SEE RESPIRATORY SYSTEM PRESERVATION, LUNG
PRESERVATION
SEE TISSUE (CELL) CULTURE, CELL CULTURE COLLECTIONS
BANKS AND REGISTRIES
SEE TISSUE PRESERVATION
PRESSORECEPTORS
SEE SENSE ORGANS, PRESSORECEPTORS
PRESSURE, ATMOSPHERIC
SEE ENVIRONMENT, ATMOSPHERIC PRESSURE
PRESSURE, BLOOD
SEE CARDIOVASCULAR FUNCTION, BLOOD PRESSURE
PRESSURE, HYDROSTATIC
SEE PHYSICAL PROPERTIES, FLUID STATE, HYDROSTATIC
PRESSURE
PRESSURE, MECHANICAL
SEE PHYSICAL PROPERTIES, MECHANICAL PRESSURE
PRESSURE GRADIENT TECHNIQUE BLOOD
SEE CARDIOVASCULAR DISORDERS DIAGNOSIS. BLOOD
PRESSURE GRADIENT TECHNIQUE*
PREVENTION
SEE CARDIOVASCUUR DISORDERS PREVENTION AND
CONTROL (NOT INCLUDED ELSEWHERE)
SEE HEALTH, DISEASE PREVENTION AND CONTROL
SEE TOXICOLOGY, POISON CONTROL AND PREVENTION
PREVENTION, TOXICOLOGY RELATED
SEE TOXICOLOGY, POISON CONTROL AND PREVENTION
PREVENTIVE MEDICINE
SEE HEALTH, DISEASE PREVENTION AND CONTROL
PRIMARY ATYPICAL PNEUMONIA
SEE RESPIRATORY DISORDERS, PNEUMONIA MYCOPLASMAL
(PPLO)
PRIMATE COLONIES
SEE MAMMALS, PRIMATE COLONIES
PRIMATES
SEE MAMMALS. PRIMATES*
PRISCOLINE
SEE IMIDAZOLES, TOLAZOLINE
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level
••Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
PRO
PROACCELERIN
SEE BLOOD COAGULATION. FACTOR V
PROBE TUBE MICROPHONE
SEE RESPIRATORY DISORDERS DIAGNOSIS. RESPIRATORY
AIRFLOW MEASUREMENTS*
PROBENECID
SEE SULFONAMIDES. PROBENECID
PROBLEM SOLVING
SEE PSYCHOLOGY, COGNITION. PROBLEM SOLVING
PROCAINE AMIDE
SEE PHENYLAMIDES. PROCAINE AMIDE
PROCAINE HYDROCHLORIDE
SEE P AMINOBENZOATE. PROCAINE HYDROCHLORIDE
PROCLORPERAZINE
SEE PHENOTHIAZINES. PROCLORPERAZINE
PROCOLLAGEN
SEE ALBUMINOIDS. COLLAGEN. PROCOLLAGEN
PROCONVERTIN
SEE BLOOD COAGULATION. FACTOR VII
PROFIBRINOLYSIN
SEE BLOOD COAGULATION. PLASMINOGEN
PROGESTERONE
SEE ALSO PROGESTINS
ROlHL-03941-18 Uterine blood flow and changes in
pregnancy (sheep)
ROlHL-12085-10 Lipoprotein-carbohydrate metabolism
(human, rats)
ROlHL-13567-06 Ion transport across cell membranes
(human)
ROlHL-13841-16 Respiration during altitude
acclimatization (goats, dogs, rats, rabbits)
POlHL-14388-07 0232 Regulation of the circulation in
pathological states - Idiopathic cyclic edema
ROIHL 1452607 Oral contraceptives and hypertension
(rats)
•* POlHL-14985-07 0015 Adaptation to hypoxia - Pregnancy
at high altitude (human, animals)
POlHL-15835-06 0002 Study of muscles related to heart
disease ■ Proteins of smooth muscle system (cattle,
rabbits)
ROlHL-16512-04 Lipoprotein metabolism and hormonal
regulation (chickens)
POlHL-18574-03 0006 Lipoprotein methodology and
biomedical applications - Lipoprotein transformation.
lipolytic enzymes, diet and lipid lowering agents
R01HL18848-03 Etiology and development of congenital
heart disease (dogs, cats)
ROlHL-19279-03 Intracellular action of aldosterone in
hypertension (human, rats)
ROlHL-20939-02 Regulation of fetal hemoglobin in
humans
ROlHL-21 112-02 Aldosterone binding, clearance, and
secretion In man
PROGESTERONE ANALOGS, CYPROTERONE
(ACETATE)
ROlHL-17516-04 Role of androgen as a risk factor in
atherogenesis (human, animals)
PROGESTERONE ANALOGS,
MEDROXYPROGESTERONE ACETATE
POlHL-14985-07 0004 Adaptation to hypoxia - Control of
breathing in respiratory failure (human, dogs)
P01HL14985-07 0008 Adaptation to hypoxia - Ventilatory
drive and exercise capacity (human, dogs)
POlHL-14985-07 0013 Adaptation to hypoxia • Chronic
mountain sickness (men)
PROGESTERONE ANALOGS, NORETHINDRONE
R01HL12557-09 Effects of steroids and pregnancy on
arteries and veins (guinea pigs)
PROGESTERONE ANALOGS, NORETHYNODREL
SEE ALSO FERTILITY. ANTIFERTILITY DRUGS. MESTRANOL-
NORETHYNODREL
ROIHL 14526-07 Oral contraceptives and hypertension
(rats)
ROlHL-19144-03 Contraceptive steroids and experimental
hypertension (rats)
PROGESTINS
SEE ALSO PROGESTERONE
POlHL-16387-04 0002 The blood vessel and
thrombogenesis - Hormonal effects on thrombogenesis
(rats, rabbits)
POlHL-18574-03 Lipoprotein methodology and biomedical
applications
R01HL19279-03 Intracellular action of aldosterone in
hypertension (human, rats)
PROGNOSIS (DISEASE RELATED)
SEE DISEASES. PROGNOSIS
PROGRAM PLANNING, BIOMEDICAL RESEARCH
SEE HEALTH SCIENCES RESEARCH ANALYSIS-EVALUATION-
PLANNING
(comd)
I
-'■:'• '."WViJTf
PRO
PROGRAM PLANNING, EDUCATION
SEE EDUCATION PROGRAMS (SYSTEMS) EVALUATION
PLANNING
PROGRAM PLANNING, HEALTH RESOURCES-
SERVICES
SEE HEALTH CARE (SERVICESXRESOURCES) PLANNING
PROGRAMMED INSTRUCTION
SEE EDUCATION, PROGRAMMED INSTRUCTION
PROGRESSIVE PATIENT CARE
SEE HEALTH CARE SERVICES. PATIENT CARE MANAGEMENT,
COMPREHENSIVE CARE
PROLACTIN
SEE PITUITARY OIENCEPHALON HORMONES, PROLACTIN
PROLACTIN, PLACENTAL
SEE REPRODUCTIVE HORMONES, CHORIONIC
SOMATOMAMMOTROPIN
PROUNE
SEE CYCLIC AMINO ACIDS. PROLINE
PROLONGED PREGNANCY
SEE PREGNANCY DISORDERS, PROLONGED PREGNANCY
PROLYLCARBOXYPEPTIDASE
SEE PROTEASES AND PEPTIDASES,
PROLYLCARBOXYPEPTIDASE
PROMETHAZINE
SEE PHENOTHIAZINES, PROMETHAZINE
PRONASE
SEE PROTEASES AND PEPTIDASES, PRONASE
PRONENESS TO DISEASE
SEE DISEASE PRONENESSRISK
1,2-PROPANEOIOL
SEE ALCOHOLS, DIOLS. PROPYLENE GLYCOL
PROPANOL
SEE ALCOHOLS, PROPANOLS
PROPANOLOL
SEE NAPHTHYUMINES, PROPRANOLOL
PROPERDIN
SEE IMMUNOLOGY, PROPERDIN
PROPIONIC ACID
SEE FATTY ACIDS, PROPIONIC ACID
PROPIONYL COA:CARBON DIOXIDE LIGASE
(ADP-FORMING)
SEE CARBON-CARBON UGASES, PROPIONYL COA
CARBOXYLASE (ATP-HYDROLYZING)
PROPIONYL COA CARBOXYLASE
SEE CARBON-CARBON UGASES, PROPIONYL COA
CARBOXYLASE (ATP-HYDROLYZING)
PROPIONYL COA CARBOXYLASE (ATP-
HYDROLYZING)
SEE CARBON-CARBON UGASES, PROPIONYL COA
CARBOXYLASE (ATP-HYDROLYZING)
PROPIONYL C0A:C02 LIGASE (ADP)
SEE CARBON-CARBON UGASES, PROPIONYL COA
CARBOXYLASE (ATP-HYDROLYZING)
PROPRANOLOL
SEE NAPHTHYLAMINES, PROPRANOLOL
PROPRIOCEPTION
SEE SENSORY-PERCEPTUAL PROCESSES, PROPRIOCEPTION
PROPYLENEGLYCOL
SEE ALCOHOLS, DIOLS, PROPYLENE GLYCOL
PROSENCEPHALON
SEE BRAIN, PROSENCEPHALON (GENERAL)
PROSTAGLANDINS
SEE FATTY ACIDS, UNSATURATED FATTY ACIDS.
PROSTAGUNDINS
PROSTAGLANDINS ANALOGS
SEE FATTY ACIDS. UNSATURATED FATTY ACIDS.
PROSTAGLANDINS ANALOGS
PROSTAGLANDINS-ASSOCIATED HYPERTENSION
SEE CARDIOVASCUUR DISORDERS. HYPERTENSION
(SYSTEMIC). PROSTAGUNDINS-ASSOCIATED
PROSTAGLANDINS METABOLISM
SEE FATTY ACIDS METABOLISM. PROSTAGLANDINS
METABOUSM
PROSTAGLANDIN SYNTHASE
SEE OXIDOREDUCTASES. PROSTAGUNDIN SYNTHASE
PROSTATE DISORDERS
SEE REPRODUCTIVE SYSTEM DISORDERS MALE, PROSTATE
DISORDERS
433
PROSTATE NEOPLASMS
SfE NEOPLASMS Of Rf PRODUCTIVE SYSTEM MALE,
PROSIATf NtOPlASMS
PROSTHESIS
SEE ALSO BIOMATERIAIS. TISSUE SUPPORTING FRAMES
SEE ALSO BIOMEDICAL ENGINEERING. BIOLOGICAL POVKER
SYSTEMS
SEE ALSO CARDIOVASCUUR PROSTHESIS
SEE ALSO ELECTRONIC STIMUUTORS (GENERAL)
SEE ALSO HEART PROSTHESIS
SEE ALSO MEMBRANE. PROSTHETIC MEMBRANES
SEE ALSO PLASTICS
SEE ALSO PROSTHETIC ORGANS AND TISSUES
SEE ALSO TISSUE COMPATIBILITY TRANSPLANT. IMPUNT
M POIHL 1519b04 Program proiecl in biological materials
PCIHL 1519504 0001 Program project in biological
materials Design and synthesis
PCIHL 15195-04 0002 Program project in biological
materials Structural and surface characterization
** POIHL 15195 04 0C03 Program project in biological
materials Mechanical evaluation and fabrication
POIHL 15195-04 0004 Program proiect in biological
materials Biological evaluation and surface interaction
studies (dogs)
** ROlHL-20251 02 A novel approach to nonthrombogenJc
polymer surfaces (sheep, cattle)
•* NOIHV 32917-08 Materials development and testing
** NOlHV-42928-07 Continued development of carbon film
deposits for prosthetics
** N01HV-82919-00 Development of percutaneous energy
transmission systems
PROSTHETIC LUNG
SEE RESPIRATORY SYSTEM PROSTHESIS, PROSTHETIC LUNG
PROSTHETIC MEMBRANES
SEE MEMBRANE. PROSTHETIC MEMBRANES
PROSTHETIC ORGANS AND TISSUES
SEE ALSO BLOOD SUBSTITUTES
SEE ALSO KIDNEY PROSTHESIS. ARTIFICIAL KIDNEY
SEE ALSO MEMBRANE. PROSTHETIC MEMBRANES
ROIHL 11945-10 Synthesis of artificial lung and kidney
systems (sheep, mice, swine)
ROIHL 22455-01 Platelet concentration in the marginal
layer (dogs, human)
** ROlHL-22585-01 Plasma proteins adsorbed to artificial
organs (human, rabbits)
** ROlHL-22627-01 An inhibitor of platelet adhesion to
artificial organs (human)
PROSTIGMINE
SEE PHENYLAMINES. NEOSTIGMINE
PROTAMINASE
SEE PROTEASES AND PEPTIDASES, CARBOXYPEPTIDASE
PROTAMINES
SEE NUCLEOPROTEINS, PROTAMINES
PROTEASE INHIBITORS
SEE ENZYME INHIBITORS, PROTEASE INHIBITORS (GENERAL)
PROTEASES AND PEPTIDASES
SEE ALSO BLOOD COAGUUTION
SEE ALSO IMMUNOLOGY, ANTIGENS BACTERIAL,
STREPTOKINASE
SEE ALSO PEPTIDES. VASOACTIVE PEPTIDES. KALUKREIN
SEE ALSO PEPTIDES. VASOACTIVE PEPTIDES, RENIN
P01HL-031 74-23 0009 Mechanisms of acute vascular
reaction to injury - Mast cell lipid interaction (human, rats)
R01HL-0318C-21 Relation of lymphatics to
cardiopulmonary function (dogs)
R01HL-12833-09 Genetic and environmental Influences on
lung disease (human)
P50HL-I4147-08 0006 Specialized center of research in
thrombosis - Clearance mechanisms of coagulation
moieties (human, rabb'ts. rodents)
POlHL-14580-07 0001 Program project in respiratory
mechanics - Micromechanics of the lung (dogs, rats)
** ROlHL-14700-05 Humoral and lung protease-antiprotease
role in obstructive disease (human)
** ROlHL-14778-10 Proteolytic enzymes and inhibitors in
lung disease (mammals, human)
P50HL-15389-07 0015 Pulmonary SCOR-Hypersensitivity
pneumonitis - Fractionation and characterization of
thermophilic Actinomycete antigens
POlHL-15486-06 0003 Studies on thrombosis -
Mechanism and prevention of fibrinopeptide B degradation
(human)
ROlHL-156 15-06 Structure-function studies of human
factor VIII/vWF
POlHL-15832-06 0009 Chemical-structural predispositions
to lung injury - Immunology-Enzyme degradation products
of human lung elastin and microfibril
POlHL-15835-06 0002 Study of muscles related to heart
disease - Proteins of smooth muscle system (cattle.
rabbits)
ROlHL-15958-06 X-ray diffraction analysis of thrombin
and neurotoxin
ROlHL-15965-06 Experimental atherosclerosis and elastin
metabolism (chicks)
POlHL-161 18-06 0004 Study of emphysema - Metabolic
activity of pulmonary connective tissue (human, hamsters)
PRO
POIHL 1638/ 04 0004 The blood vetul ind
thrombogenesis Analysis o( vajcultr biMmenl membran*
by enzymatic methods (hum*n)
ROIHL 1663/ 04 Development and regression of cardiac
hypertrophy (rats)
POIHI 16748 05 0001 Cellular and tmmunologicil biiit
o( pulmonary diseases Mechanisms of alveolar
macrophage (unction and dysfunction (human, rabbits)
POIHL 16/69 05 0004 Palhobiologic and host defense
reactions in the lung Pathogeneju ot Pieudomonas and
Serratia pneumonias (rabbits)
ROIHL 1692002 Proteases in normal and immunologically
injured lung (guinea pigs, rabbits)
POIHL 1741904 0007 Studies on mechanisms ot
hemostasis Structural analysis ol ordered (orms of
fibrinogen (human, cattle)
ROlHL-17479-04 Blood storage The production ot
cardiotoxic material (dogs, human, swine)
ROIHL 1/551-04 Biosynthesis and metabolism ot
procollagen (human, monkeys, mice)
P50HL 1/648 04 0025 Study of ischemic heart disease
Destruction and repair ot cardiac muscle cell constituents
(rat)
ROIHL 17964 04 The alternate pathway for fibrinolysis
(human)
R01HL18012 04 Cellular defects in nocturnal
hemoglobinuria (human)
ROlHL-18533-03 Microcrystalline and crystalline fibrinogen
(cattle, bacteria)
ROlHL-18714-04 Cardiovascular matrix Morphogenesis
and maturation (human, chick embryo, mammal)
POlHL-18827 02 0007 Platelet vessel wall interactions in
thrombogenesis Biochemistry and role factor V in
thrombogenesis (human, cattle)
ROIHL 19072-03 Modification of tissue iniury in
myocardial infarction (dogs, human)
* ROlHL-19/21-03 Lung inflammation -Lysosomal proteases
and liposomes (human, rabbits)
ROlHL-19777 03 Regulation of hypersensitivity in the lung
(rats, guinea pigs, rabbits, human)
POlHL-20552-02 0001 The development and regression of
cardiac hypertrophy Biochemical events in cardiac
hypertrophy (rats)
ROlHL-20711-01 Structure-function relationships in red
cell NA-K pumps (goats)
POlHL-20984-02 0004 Cellular mechanisms in cardiac
hypertrophy - Myofibril accumulation in cardiac and
vascular muscle cells in hypertrophy
POlHL-20994-02 0009 Dynamics of neutrophil elastase in
the lung - Biosynthesis and degradation of elastin in
emphysema (human, hamsters)
ROlHL-21120-02 Membrane dynamics in alveolar
macrophages (rabbits)
ROlHL-2 11 56-02 Antitrypsin and other causes of chronic
lung disease
ROlHL-21274-01 Prorenin -Physiological and biochemical
analysis (human)
ROlHL-21376-02 Blood-gas barrier solute and water
transport (rabbits)
ROlHL-21769-01 Blood compatible benzamidine containing
polymers
R01HL-22052-01 Organization of free cholesterol in serum
lipoproteins (human, dogs)
R01HL-22257-01 Leukokinesis enhancing factor and lung
infections (human, rats)
** R01HL-22266-01 Production of proteases by lung cells in
culture (human, rodents, rabbits, sheep)
** ROlHL-22530-01 Active site studies on blood proteases
Control of protein metabolism in heart
(human)
ROlHL-22651-01
muscle
** ROlHL-22676-01 Pathogenesis in experimental interstitial
pneumonitis (rabbits)
ROlHL-22985-01 Properties and assembly of Z-disk
proteins (human, other species)
ROlHL-23593-01 Mast cell granules-Structure and
secretion (rats)
PROTEASES AND PEPTIDASES,
ANGIOTENSINASE
P50HL-14187-07 0014 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses - Metabolism
and actions of vasoactive peptides in lung (human.
mammals)
ROlHL-16920-02 Proteases in normal and immunologically
injured lung (guinea pigs, rabbits)
** POlHL-17813-04 0008 Lung disease and the oxygenation
of blood and tissue - Pulmonary regulation of systemic
blood pressure (human, rabbits, rats)
P50HL-18318-03 0015 Pathogenesis and complications of
hypertension Cultured smooth muscle cells and
microvessel metabolism (mammals)
** ROIHL 18908-03 Angiotensin converting enzyme of human
serum
** ROlHL-19077-01 Biochemistry and molecular biology of
sarcoidosis (human, rabbits)
ROlHL-19237-03 Obstructive lung disease and alveolar
macrophages (human, animals)
R01HL-20366-03 Protein turnover and amino acid
transport by lung (rats)
R23HL-21189-01 Regulation of pulmonary endothelial cell
activities (human, cattle)
(contd)
•Excludes routine methodology OR covers only general projects which preclude
**Oriented significanthf to above subject.
indexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
PIO
R23HL-21894-01
(cattle)
ROlHL-22242-01
human)
ROlHL-2238701
Pulmonaty angiotensin converting enzyme
The converting enzyme of lung (cattle.
Metalloenzymes and disease
MOTEASES AND PEPTIDASES,
CARBOXYPEPTIDASE
R01HLie320-0S Vasoactive peptides which stimulate
smooth muscles (rats, human)
R01HL1692002 Proteases in normal and immunologically
Injured lung (guinea pigs, rabbits)
ROlHL-22387-01 Metalloenzymes and disease
PROTEASES AND PEPTIDASES, CATHEPSIN B
POlHl-20993-02 0006 Population dynamics of arterial
cells in atherogenesis - Mechanism of regression of
atherosclerosis by diet and injury (swine)
PROTEASES AND PEPTIDASES, CATHEPSINS
POlHL-06296-18 0005 Cardiovascular and pulmonary
adaptation to stress - Regulation of ventricular
performance (animals)
P50HL-U153-07 0004 Johns Hopkins Lung Center-
Chronic diseases of airways - Macrophage enzymes in lung
injury, inflammation and repair (rabbit)
R01HL1477810 Proteolytic enzymes and inhibitors in
lung disease (mammals, human)
POIHL'ie387-04 0004 The blood vessel and
thrombogenesis - Analysis of vascular basement membrane
by enzymatic methods (human)
ROlHL-1692002 Proteases in normal and immunologically
injured lung (guinea pigs, rabbits)
** PSOHl- 1766904 0011 Ischemic heart disease center
(SCOR) ' Lysosomal function and lysosomal enzymes in
normal and ischemic heart (rabbit)
ROIHL' 18087-03 Development and regression of cardiac
hypertrophy (rats, rabbits)
R01HL'181S704 Subcellular events in atherosclerosis
(human, rabbits, calves)
R01HL18679'04 Synthetic protease inhibitors
ROlHL-19648'03 Myocardial protein degradation (dogs.
rabbits)
ROlHL'19721-03 Lung inflammation-Lysosomal proteases
and liposomes (human, rabbits)
ROlHL'20104-03 Pulmonary granulomatous inflammations
(mice)
RDlHL-2028302 Maintenance of cellular Integrity in
ischemic hearts (cats)
PROTEASES AND PEPTIDASES, CHYMOTRYPSIN
ROlHL'14262-07 Leukocyte proteases and their lung
targets (human, dogs, rabbits)
R01HL15892'05 Inhibitors of proteinases (human, cattle.
swine)
ROlHL-22996-01 Venom proteases -Action on plasma
protease inhibitors (human)
PROTEASES AND PEPTIDASES, COLLAGENASE
P50HL-14153-07 0004 Johns Hopkins Lung Center-
Chronic diseases of airways - Macrophage enzymes in lung
Injury, inflammation and repair (rabbit)
** POlHL-15832-06 0004 Chemical-structural predispositions
to lung Injury - Proteolytic activity leucocytes in patients
with obstructive lung disease
POlHL-1611806 0003 Study of emphysema Degradation
of collagen and elastin (human, hamsters, mice)
POlHL-161 18-06 0004 Study of emphysema ■ Metabolic
activity of pulmonary connective tissue (human, hamsters)
POlHL-161 18-06 0005 Study of emphysema -
Mechanisms of elastase emphysema (mice)
POlHL-16387-04 0004 The blood vessel and
thrombogenesis - Analysis of vascular basement membrane
by enzymatic methods (human)
ROlHL-16920-02 Proteases in normal and immunologically
injured lung (guinea pigs, rabbits)
POlHL-18576-03 0004 Thrombosis research program
project - Mechanism and control of collagen-platelet
interaction
P01HL18576-03 0011 Thrombosis research program
project - Proteolysis and platelet function (human, cattle.
rabbits)
R0IHL18679-04 Synthetic protease inhibitors
ROlHL-1913603 Mucopolysaccharide metabolism in
cardiac anomalies (rats)
ROlHL-19237-03 Obstructive lung disease and alveolar
macrophages (human, animals)
POlHL-19717-02 0010 Response of the lung to injury -
Proteoglycans In lung function and structure (hamsters)
R01HL-I9721'03 Lung inflammation-Lysosomal proteases
and liposomes (human, rabbits)
R01HL19774-03 Pathogenesis of chronic lung disease
(rats, mice, bacteria)
ROlHL-20104-03 Pulmonary granulomatous inflammations
(mice)
ROlHL-20533-09 Pathogenesis of rheumatic fever (human,
rabbits)
POlHL-20993-02 0006 Population dynamics of arterial
cells in atherogenesis - Mechanism of regression of
atherosclerosis by diet and injury (swine)
ROlHL-2 11 20-02 Membrane dynamics in alveolar
macrophages (rabbits)
ROlHL-2 1376-02 Blood-gas barrier solute and water
transport (rabbits)
434
R23HL-22490-01 Neurotransmitter receptors of cultured
heart cells
ROlHL-22729-01 Intracellular degradation of newly
synthesized collagen (human, chick, rabbit)
PROTEASES AND PEPTIDASES, DIPEPTIDASES
P50HL-14187-07 0014 Pulmonary SCOR -Chemical
mediators in pulmonary vascular responses - Metabolism
and actions of vasoactive peptides in lung (human,
mammals)
PROTEASES AND PEPTIDASES, ELASTASE
SEE ALSO ENZYME INHIBITORS, EUSTASE INHIBITORS
ROlHL-09739-13 Biophysical studies of proteins (human)
POlHL-13262-07 0015 Arterial wall in atherosclerosis -
Crosslinkage biosynthesis in aortic elastin and collagen
(animals)
P50HL 14153-07 0004 Johns Hopkins Lung Center-
Chronic diseases of airways - Macrophage enzymes in lung
injury, inflammation and repair (rabbit)
" ROlHL-14262-07 Leukocyte proteases and their lung
targets (human, dogs, rabbits)
ROlHL-14700-05 Humoral and lung protease-antiprotease
role in obstructive disease (human)
ROlHL-14778-10 Proteolytic enzymes and inhibitors in
lung disease (mammals, human)
ROlHL-14865-07 Biochemical studies on the pathogenesis
of emphysema (human, rats)
** POlHL-15832-06 0004 Chemical-structural predispositions
to lung injury - Proteolytic activity leucocytes in patients
with obstructive lung disease
ROlHL-15892-05 Inhibitors of proteinases (human, cattle,
swine)
** ROlHL-15979-05 Elastase, serum inhibitors and the
vasculature (human, swine)
POlHL-161 18-06 0003 Study of emphysema - Degradation
of collagen and elastin (human, hamsters, mice)
** POlHL-161 18-06 0004 Study of emphysema ■ Metabolic
activity of pulmonary connective tissue (human, hamsters)
" POlHL-161 18-06 0005 Study of emphysema ■
Mechanisms of elastase emphysema (mice)
POlHL-16387-04 0004 The blood vessel and
thrombogenesis - Analysis of vascular basement membrane
by enzymatic methods (human)
POlHL-16748-05 0001 Cellular and immunological basis
of pulmonary diseases - Mechanisms of alveolar
macrophage function and dysfunction (human, rabbits)
ROlHL-16920-02 Proteases in normal and immunologically
injured lung (guinea pigs, rabbits)
ROlHL-18679-04 Synthetic protease inhibitors
ROlHL-19237-03 Obstructive lung disease and alveolar
macrophages (human, animals)
** POlHL-197 17-02 0003 Response of the lung to injury -
The role of elastolysis in emphysema (hamsters, rabbits)
POlHL-19717-02 0005 Response of the lung to injury -
Studies on proteolysis and lung disease (human, animals)
POlHL-19717-02 0008 Response of the lung to injury -
Experimental models of lung disease
** POlHL-197 17-02 0012 Response of the lung to injury -
Connective tissue biochemistry and enzyme injury of the
lung (hamsters)
" POlHL-19717-02 0022 Response of the lung to injury -
Localization of enzymes and sites of action in experimental
emphysema (hamsters)
ROlHL-19721-03 Lung inflammation-Lysosomal proteases
and liposomes (human, rabbits)
ROlHL-20104-03 Pulmonary granulomatous inflammations
(mice)
ROlHL-20220-03 Anaphylatoxins as inflammatory and
chemotactic agents (guinea pig. rabbit, human)
ROlHL-20875-02 Chronic obstructive pulmonary disease-
Familial/genetic (human)
M POlHL-20994-02 Dynamics of neutrophil elastase in the
lung
** POlHL-20994-02 0001 Dynamics of neutrophil elastase in
the lung - Dynamics of neutrophil elastase in normal
animals (dogs, rabbits)
** POlHL-20994-02 0002 Dynamics of neutrophil elastase in
the lung - Neutrophil and neutrophilic elastase in human
lungs
** POlHL-20994-02 0003 Dynamics of neutrophil elastase in
the lung - Neutrophil elastase flux in models of lung
disease (dogs)
POIHL 20994-02 0005 Dynamics of neutrophil elastase in
the lung - Protease inhibitors in pulmonary inflammation
and emphysema (rabbits)
** POlHL-20994-02 0007 Dynamics of neutrophil elastase in
the lung - The etiology of experimental emphysema (dogs)
ROlHL-21376-02 Blood-gas barrier solute and water
transport (rabbits)
** R23HL-22437-01 Leukotactic mediators in lung
inflammatory reactions (rats, rabbits, human)
ROlHL-23595-01 Experimental emphysema-Depression of
protease inhibitors (rats, hamsters)
PROTEASES AND PEPTIDASES, GLUTAMYL
CYCLOTRANSFERASE
ROlHL-12972-09 Glutathione deficiency in red cells
(sheep, dogs)
PRO
PROTEASES AND PEPTIDASES, GLUTAMYL
TRANSPEPTIDASE
P50HL 14230-07 0099 A/S SCOR -Lipids, atherosclerosis
and thrombosis - Morphological, cytochemical study of
normal and altered vasculature (mice)
** ROlHL-21 105-02 Organ specific drugs-Cardiovascular and
renal effects (dogs)
PROTEASES AND PEPTIDASES, PAPAIN
ROlHL-17543-03 0004 Magnetic tracers for diagnosis of
lung disease - Magnetite retention, distribution, relaxation
rate, viscosity (rabbits)
PROTEASES AND PEPTIDASES, PEPTIDASES
ROlHL-21303-02 Collagen synthesis by cultured human
vascular cells
ROlHL-22896-01 Immediate metabolic fates of kinins and
angiotensins (rat. rabbit, guinea pig)
PROTEASES AND PEPTIDASES,
PROLYLCARBOXYPEPTIDASE
ROlHL-16320-05 Vasoactive peptides which stimulate
smooth muscles (rats, human)
PROTEASES AND PEPTIDASES, PRONASE
ROlHL-17571-03 Study of membrane permeability by NMR
relaxation (human)
PROTEASES AND PEPTIDASES, THERMOLYSIN
ROlHL-18679-04 Synthetic protease inhibitors
PROTEASES AND PEPTIDASES, TRASYLOL
P01HL-O6370-17 0014 Cardiopulmonary and renal
pathology research center ■ Quantitative morphology in
cardiac disease (human, rats, dogs)
ROlHL-14692 06 Alpha 1 antitrypsin deficiency and
pulmonary disease (human)
ROlHL-18579-03 Vasoactive hormones and blood pressure
regulation (dogs. rats, rabbits)
ROIHL 20283-02 Maintenance of cellular integrity in
ischemic hearts (cats)
ROlHL-21540-02 Specific inhibitors of coagulation and
fibrinolysis (rats, rabbits, dogs)
PROTEASES AND PEPTIDASES, TRYPSIN
ROlHL-01662-25 Equilibria in the fibrinogen-fibrin
conversion (human, cattle)
ROlHL-09739-13 Biophysical studies of proteins (human)
POlHL-12157-11 0055 Functions and mechanisms of cell
membrane ion transport Growth and development of
synthetic strand heart cells in culture (chick embryo)
ROlHL-15958-06 X-ray diffraction analysis of thrombin
and neurotoxin
ROlHL-19429-03 Phagocytosis-lngestion in alveiolar
macrophages (rabbits)
ROlHL-22996-01 Venom proteases-Action on plasma
protease inhibitors (human)
PROTECTIVE GROUPS (CHEMISTRY)
SEE CHEMICAL REACTION SITES. PROTECTIVE GROUPS
PROTEIN BINDING
SEE ALSO BIOLOGICAL TRANSPORT. TRANSPORT PROTEINS
(SEE ALSO SPECIFICS)
SEE ALSO CARBOHYDRATES. PROTEIN BOUND
CARBOHYDRATES
SEE ALSO ENDOCRINOLOGY. HORMONE BINDING PROTEINS
SEE ALSO HALOPROTEINS. PROTEIN BOUND IODINE
SEE ALSO PROTEINS. Z PROTEIN
R01HL-01803-23 0015 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Immunologic endothelial injury and lipid
diet atherosclerosis (rabbits, monkey)
ROlHL-02751-21 Function and metabolism of serum
albumin (mammals, fish, amphibians)
ROlHL-05556-19 Proteins. lipoproteins-Structure and
reactivity (chicken, human, diving mammals)
POlHL-06314-17 0047 Immunologic mechanisms in
cardiovascular disease - Role of intravascular coagulation
(human, animals)
POlHL-0631417 0051
cardiovascular disease
*Eidiidn nwtint mettudotofy OR covers only general projects which preclude indexing at the specific level.
* Siicr^H 'if nificsntly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
Immunologic mechanisms in
Conformational studies of
phospholipid membranes and proteins
POlHL-06314-17 0064 Immunologic mechanisms in
cardiovascular disease • Diabetic vascular disease (human.
rats, mice)
ROlHL-10316-13 Structural studies on low density serum
lipoproteins (human)
POlHL-12157-11 0033 Functions and mechanisms of cell
membrane ion transport - Immunology aspects of active
Na-K transport in sheep red cell (also human, mice)
P01HL13262-07 0016 Arterial wall in atherosclerosis -
Lipids in elastin preparations from atherosclerotic plaques
(human, animals)
ROlHL-13870-09 Control of myocardial sarcotubular
calcium stores (dogs)
ROlHL-13921-07 The lung as a metabolic organ (animals)
P50HL-14147-08 0001 Specialized center of research in
thrombosis - Role of aspirin, other anti-platelet agents in
platelet function (rat. human)
P50HL-14147-08 0003 Specialized center of research in
thrombosis - Surface thrombogenicity and phospholipid
vesicle physical properties
(contd)
PRO
PbOHL MM/ 08 0018 Sptcialued centei ol resoaich in
thrombosis Biochemical aspects ot platelet function in
thrombosis and cell irowth (human)
P50HL 14164 07 003b A/S SCOR Comparative and
experimental atherosclerosis Lipid metabolism Inteiaction
with arterial metabolism (monkey, pigeon)
PbOHl 14197 07 000b Support lor center ol research on
arteriosclerosis Lipoprotein biosynthesis and degiadation
in vivo and in vitro (human, animal)
PbOHL 14214 07 0023 Newborn lung center loi hyaline
membrane disease Regulation ot letal lung maturation
Vitamin A (rat, rabbit, sheep, human)
P50HL14217 08 00b4 Specialijed centei of research in
thrombosis Coagulation section Platelet aggregation
(human, pig. rabbit, dog)
PbOHL 14217 08 OObS Specialized center of research in
thrombosis Energy metabolism and platelet function
(human)
PbOHL 1421708 0062 Specialized center of research in
thrombosis Coagulation section -Factor VIII and Factor XII
(human, cattle)
PbOHL 14230 07 0092 A/S SCOR-Lipids. atherosclerosis
and thrombosis Tissue lipids -Cell culture studies
(human)
PbOHL 14230-07 0098 A/S SCOR Lipids, atherosclerosis
and thrombosis Molecular properties of factor VIII (cattle,
human, mice)
PbOHL 14237 07 0002 Support for arteriosclerosis center
■ Interactions of lipoprotein particles viith vascular surface
(human, rat)
P50HLlb062 07 0019 Study of lipoproteins, artery wall,
and atherosclerosis Factors regulating lipoproteinsmooth
muscle cell interaction (monkey)
P60HLlbl60-07 0008 Center for sickle cell disease
Isocyanate derivatives and hemoglobin S association
(human, rat)
R01HL-lb226-06 Interaction of blood cells with tibrinogen
and fibrin (human, animals)
R01HL-lb34106 Lung hormonal and chromosomal
regulation (rats, rabbits)
P01HL-lbb96-0b 0017 Coagulation, fibrinolysis,
hemostasis and hepatitis - Heparin and antithrombin III
R01HLlb692-07 Force and speed in skeletal and cardiac
muscle
R0IHLlb698-12 Factors aflecting the action of
anticoagulants (rats, human)
ROIHL lb799-04 Effect of anesthetics on myocardial
function (cats)
P01HL-lb83206 0011 Chemical-structural predispositions
to lung injury ■ Interaction of cell receptors with vasoactive
agents in pulmonary vascular bed
P01HL-lb83b-06 0001 Study of muscles related to heart
disease - Control of contraction-relaxation of heart and
muscle (rabbits, chickens)
P60HL-lb999-0b 0014 Miami comprehensive sickle cell
center Biochemical and morphological parameters of
sickle cells (human)
ROlHL-16101-Ob Protein-lipid interaction (bacteria,
models)
P01HL-162bl-06 0002 Membrane-bound enzymes in heart
and other tissues - Structural basis of regulation of
cardiac succinate dehydrogenase
R01HL16646-0b Pathobiology of thromboembolic disorders
(human)
R01HL16720-02 Platelet aggregation (human)
P60HL-1726b-04 0003 Community blood resource center
support ■ Research -Human factor IX-Role in intrinsic
clotting (also baboons, dogs)
P60HL- 17269-04 0009 National heart and blood vessel
research and demonstration center - Physical methods
laboratory (high density lipoproteins)
P60HL- 17269-04 0011 National heart and blood vessel
research and demonstration center - Lipoprotein structure
laboratory (human)
P60HL-17269-04 0013 National heart and blood vessel
research and demonstration center - Peptide synthesis
laboratory (human)
P60HL17269-04 0014 National heart and blood vessel
research and demonstration center ■ Physio-chemical nature
of lipid deposits in arterial wall (human)
P60HL17269-04 001b National heart and blood vessel
research and demonstration center - Lipoprotein
metabolism laboratory (human)
P60HL-17269-04 0017 National heart and blood vessel
research and demonstration center - Cell membrane (dogs,
rabbits)
" R01HL-17b25-03 Molecular basis of collagen-platelet
interaction (human, rat)
R01HL-17b96-03 Leukocyte-endothelial interactions (rats)
ROlHL-17623-Ob Initial events in thrombus formation on
surfaces (human, rats)
PbOHL-17682-04 0024 Study of ischemic heart disease -
Phosphorylation of cardiac contractile proteins during
ischemia (rat, guinea pig)
ROlHL-17844-04 Artificial blood substitutes-02-binding
iron chelates (human, mammals)
** ROlHL-17898-03 Cell membranes and plasma lipoproteins
(human, swine)
** ROlHL-18179-03 Heart, platelet, and muscle myosins and
actomyosins (cattle)
R01HL-18bl9-03 Albumin, endothelium and
hemocompatibility (human, dog, cattle, rabbit)
435
ROllll 18bbJ03 Membrane detects in lamilial
hypoicholesteiemia (human)
ROIHI 18619 03 Transfeiiin iron binding and Iraniport
properties (chicken, rabbit, human)
ROIHL 18634 03 Quartemaiy structure of erythro and
chlorocruoiins (invcrtebiates)
POIHL 1864b 03 0004 Biology of the artery wall and
atherosclerosis Human arterial smooth muscle cell and
lipoprotein interaction
ROIHL 188b0 03 Platelet collagen interaction (human)
ROIHL 18714 04 Cardiovascular matrix Morphogenesis
and maturation (human, chick embiyc, mammal)
ROIHL 18819 07 Chemical studies on sickle cell
hemoglobin (human)
PbOHL 18828 03 0001 Specialized center of research in
thrombosis Membrane biology and hemostasis (human)
PbOHL 1882803 0002 Specialized center of research in
thrombosis Endothelial cell biology (human, guinea pig)
PbOHL 1882803 0003 Specialized center of research in
thrombosis Structure and function of plasma coagulation
inhibitors (human)
PbOHL 1882803 0006 Specialized center of research in
thrombosis Etiology and pathogenesis of atherosclerosis
(rabbit, monkey, rat, human)
PbOHl 1882803 0009 Specialized center of research in
thrombosis Platelet formation and megakaryocyte cell
biology (guinea pig, human)
ROlHL-1883404 Metal-dependent complex formation in
blood coagulation (human, cattle)
ROIHL- 18878-03 Familial hypercholesteremia -Studies of
fibroblasts (human)
ROlHL-19132 04 Role of zinc transferrin in lymphocyte
transformation (human)
ROlHL-19429-03 Phagocytosis -Ingestion in alveiolar
macrophages (rabbits)
R01HL194b9-03 Dynamics of atherogencsis and
lipoprotein formation (human, rabbit)
R23HL 1960b-01 Lipid requirement of the lung mono-
oxygenasc system (rabbits)
• R01HL19836-03 Kinin inhibitors detected by use of
receptors (cattle)
ROlHL-19982-02 Blood coagulation -Protein-metal lon-lipid
interactions
ROlHL-19996-02 Role of membrane proteins in platelet
function (human, rabbits)
ROlHL-20061-02 Serum lipoproteins and cell cholesterol
metabolism (rats, human)
ROlHL-201 14-02 Collagen-platelet interaction and human
aorta collagen (human)
ROlHL-20142-02 Functional studies of abnormal human
hemoglobins
ROlHL-20161-02 Role of gamma-carboxyglutamic acid in
blood coagulation (human, cattle)
R01HL-202bl-02 A novel approach to nonthrombogenic
polymer surfaces (sheep, cattle)
ROlHL-20391-03 Polydisperse LDL- Structure, metabolism
and function (human)
ROlHL-20666-02 Cell biology of platelet preservation
(human)
ROlHL-20794-02 Prostaglandin synthesis in human
platelets (also in sheep, rabbit)
R01HL-20882-02 Interactions of plasma lipoproteins with
erythrocytes (Rhesus, human)
PbOHL 21006-02 0003 Specialized center of research in
arteriosclerosis - Transport of vitamin A in plasma (human,
rat)
POlHL-21016-02 0014 Sickle cell anemia and other
hemoglobinopathies - Human hemoglobin mutants with
abnormal oxygen binding
ROlHL-21096-02 Sickle cell crisis-Role of the erythrocyte
membrane (human)
R23HL-2 1128-02 ATP utilization in platelet contractile
mechanisms (human, rabbits)
R23HL-211b0-02 Regulation of airway mucous glands and
ion transport (dogs, ascaris)
R23HL-21189-01 Regulation of pulmonary endothelial cell
activities (human, cattle)
** R23HL-214 13-02 Structure and function of platelet
calcium-binding protein (human)
ROlHL-21429-02 Transport of LDL in arterial wall (human,
mammals)
R01HL-21b43-02 Structure-function relation of blood
clotting proteins (rabbits)
R01HL-21626-0I Proteoglycans of animal lung
parenchyma (cattle, pigs, rabbits)
ROlHL-21692-02 Purification of erythropoietin (human)
R23HL-21894-01 Pulmonary angiotensin converting enzyme
(cattle)
R01HL-220b3-02 The disordered lipid metabolism of
diabetes mellitus (chickens, mammals, human)
** ROlHL-22081-20 The mechanism of collagen formation
(human, cattle)
ROlHL-22239-01 The molecular basis of electrical
excitability (chick embryos, rats)
ROlHL-22270-01 Platelet glycoprotein (human)
** R01HL-2232b-01 Thermodynamics in respiratory protein
binding (human, trout)
ROIHL 22b83-02 Ultrastructural study of endothelium in
thrombosis (human)
ROlHL-22771-01 Thrombogenic phospholipid surfaces
(cattle)
PRO
ROIHI 228/b 01 CioliliM Chtmiilry. phytiology, clinical
potential (lats. rabbits)
ROIHI 2298301 Studies on the c8taboli%m ot plaima
lipoproteins dais)
ROIHI 23010 01 Control and mechanitm of platelet
aggregation (human)
ROIHt 23161 01 000b Biology of myocardial I'.chemia
Localization of complement in myocardial infarction (dog)
•* ROIHL 23200 01 Isolation of CA binding protein-, from
erythrocytes (human)
ROIHL 23b93 01 Mast cell granules Structure and
secretion (rats)
NOIHV 42984 Ob Interactions of modified biopolymers with
blood (humans, rats)
PROTEIN BOUND CARBOHYDRATES
SEE CARBOHYORAIES. PROTEIN BOUND CARBOHYDRATES
PROTEIN BOUND IODINE
SEE HALOPROTEINS. PROTEIN BOUND IODINE
PROTEIN DEFICIENCY
SEE NUTRITIONAL ABNORMALITIES, PROTEIN DEFICIENCY
PROTEIN KINASE
SEE PHOSPHOTRANSFERASES. ATP PROTEIN
PHOSPHOTRANSFERASE
PROTEIN-POLYSACCHARIDE COMPLEXES
SEE PROTEOGLYCANS
PROTEIN STRUCTURE
SEE PROTEINS PEPTIDES STRUCTURE
PROTEINOSIS
SEE PROTEINS METABOLISM DISORDERS, PROTEINOSIS
PROTEINS
SEE ALSO ALBUMINOIDS
SEE ALSO ALBUMINS
SEE ALSO AZOPROTEINS
SEE ALSO BLOOD PROTEINS
SEE ALSO FIBROUS PROTEINS
SEE ALSO GLOBINS
SEE ALSO GLOBULINS
SEE ALSO GLYCOPROTEINS
SEE ALSO IMMUNOLOGY, ACUTE PHASE PROTEINS
SEE ALSO IMMUNOLOGY, ANTIGENS BACTERIAL, M PROTEIN
SEE ALSO LIPOPROTEINS
SEE ALSO METALLOPROTEINS
SEE ALSO MUSCLE PROTEINS (AND CONTRACTILE PROTEINS)
SEE ALSO NUCLEIC ACIDS, MRNA
SEE ALSO NUTRITION, DIETARY CONSTITUENTS, DIETARY
PROTEINS
SEE ALSO PEPTIDES
SEE ALSO PHOSPHOPROTEINS
SEE ALSO PLANTS PROTEINS
SEE ALSO PROTEOGLYCANS
SEE ALSO PROTEOLIPIDS
SEE ALSO RESPIRATORY PROTEINS (GENERAL)
R01HL-04bl2-19 Ultrastructural studies of capillary
permeability (rats, mice)
P01HL-0628b-18 014b Cardiovascular-respiratory
physiology and biochemistry - Pulmonary, pleural and
systemic microcirculation (animals)
P01HL-0628b-18 0213 Cardiovascular-respiratory
physiology and biochemistry - Membrane structure and
function -Gas vacuole membrane (Halobacterium)
POlHL-06314-17 0046 Immunologic mechanisms in
cardiovascular disease - Mediators of immune injury
(human, mice)
POlHL-06314-17 OObO
cardiovascular disease
Immunologic mechanisms in
Physiologic changes in
lymphocytes (human, mice)
P01HL0880b-lb 0048 Regulation of ventilation and
pulmonary circulation - Permeability of alveolo-Capillary
membrane in normal pulmonary hypertensive lung
ROIHL 12760-09
proteins
ROlHL-13336-09
platelets
ROlHL-16233-Ob
Surface studies of membrane lipids and
Biochemistry and physiology of human
Molecular cardiology of MDP-induced left
ventricular failure (dogs)
ROlHL-16666-Ob Micropinocytosis in isolated capillary
endothelium
POlHL-16833-04 0014 Hemoglobin and red cell system in
hemoglobinopathiss - Erythrocyte membrane damage in Hb
SS disease (human)
ROlHL-18226-04 Mechanism of oxygen supply to tissue
(human, animals)
ROlHL-20241-02 Shear and area moduli for abnormal red
cell membranes (human)
R23HL-211bO-02 Regulation of airway mucous glands and
ion transport (dogs, ascaris)
ROlHL-21246-02 Roles of cholesterol and its metabolic
regulation (CHO cell mutants)
ROlHL-21282-01 Dynamics of interstitial space in whole
animals (rats)
ROlHL-21342-02 Isolation and analysis of sodium channel
from heart (frogs)
' R01HL-2199b-01 Protein phosphorylation and adrenergic
effects
R01HL-22b69-02 Intestinal secretion -Capillary and tissue
forces (dogs, cats)
(contd)
•Excludes routine methodology OR covers only general projects which preclude indexing
**Ofiented significantly to above subject.
at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
PRO
PROTEINS, BACTERIAL (GENERAL)
SEE ALSO PIGMENTS. BACTERIAL, BACTERIORHODOPSIN-
RETINAL
SEE ALSO RESPIRATORY PROTEINS, REOOXINS
" ROlHL-01803-23 0001 Arteriosclerosis, glomerulonephritis,
rheumatic fever • Poststreptococcal glomerulonephritis
(rabbit)
** POlHL-06285-18 0213 Cardiovascular-respiratoiy
physiology and biochemistry ■ Membrane structure and
function-Gas vacuole membrane (Halobacterium)
ROlHL-1610105 Protein-lipid interaction (bacteria,
models)
PROTEINS, MEMBRANE PROTEINS
SEE ALSO DRUGS RECEPTORS
SEE ALSO ENDOCRINOLOGY, HORMONE RECEPTORS
SEE ALSO NEUROTRANSMinERS RECEPTORS
POIHL 1273810 0135 Physiologic pharmacology and its
clinical applications - Myocardial cells in tissue culture
(rats, chick embryo)
** ROIHL 15616-04 Platelet membrane proteins in
aggregation (human)
POlHL-16851-04 0006 Human red cell membrane in
health and disease - Hexose transport and erythrocyte
membrane proteins (human)
ROIHL 17878-04 Structural studies of the human
erythrocyte membrane
** R01HL17879-04 Molecular structure of the ouabain
sensitive ATPase (dogs)
ROlHL-1816304 Red cell membrane effects due to
oxidizing agents
** POIHL-1820804 0007 Center for the study of blood cell
rheology - RBC membrane protein (human)
ROlHL-19068-03 Changes in membrane properties during
erythropoiesis (chick embryo)
** ROlHL-19996 02 Role of membrane proteins in platelet
function (human, rabbits)
** R01HL-20I40-02 Glycoproteins of platelet membrane and
platelet function (human)
ROlHL-2019702 Maintenance and repair of vascular
endothelium (human, animals)
ROlHL-2036503 Molecular mechanisms of anion transport
** ROlHL-2097110 Membrane glycoproteins of platelets and
leukocytes (human)
ROlHL-21120-02 Membrane dynamics in alveolar
macrophages (rabbits)
ROIHL 21404-01 Raman spectroscopy of erythrocyte and
model membranes (human)
ROlHL-21995-01 Protein phosphorylation and adrenergic
effects
ROlHL-22432-01
membranes
ROlHL-2248601
cells (swine)
ROlHL-22502-01
platelet secretion
POlHL-22602-01 0001 Pathophysiology of the
endothelium - Platelet-endothelial interactions in vitro
(human, cattle)
POlHL-22619-01 0003 Cellular mechanisms of heart
failure - Digitalis induced inotropy in myocardial ischemia
heart failure (animals)
Molecular studies of human erythrocyte
Enzyme regulation in cultured arterial
Role of phosphoinosilides in human
ROlHL-23013-01
(chick embryo)
ROlHL-2310801
(human)
ROlHL-2320001
Smooth muscle development in vitro
Membrane biochemistry of RH antigens
Isolation of CA binding proteins from
erythrocytes (human)
PROTEINS, MEMBRANE PROTEINS, SPECTRIN
ROlHL-02063-23 Biochemistry and function of lipids and
cell membranes (human, yeast, animals)
P60HL-15157-07 0018 Comprehensive center for sickle
cell disease - Red blood cell membrane physiology in sickle
cell anemia (human)
** ROlHL-17411-04 Molecular studies of red blood cell
spectrin (human)
POlHL-18208-04 0007 Center for the study of blood cell
rheology - RBC membrane protein (human)
ROlHL-21469-01 Active transport and effect of CAOO in
sickle cell (human)
PROTEINS, VIRAL (GENERAL)
P01HL-1131012 0100 Mechanisms of cardiovascular
disease - Structure and replication of arenavirus and
Bunyamweraviruses
** ROlHL-23588 01 NOV infection-Analysis at the subcellular
level (chickens)
PROTEINS, Z PROTEIN
** R01HL17194-03 Comparison of two inherited forms of
alpha-1-antitrypsin (human)
** P60HL-1 7269-04 0021 National heart and blood vessel
research and demonstration center - Growth and
development of heart -Ultrastructure (dog, guinea pig, rat,
cat)
** ROlHL-2298501 Properties and assembly of Zdisk
protems (human, other species)
PROTEINS BIOSYNTHESIS
SEE ALSO AMINO ACYL TRNA
SEE ALSO CELL COMPONENTS, POLYSOMES
SEE ALSO CELL COMPONENTS, RIBOSOMES
SEE ALSO GENETICS, GENETIC CODING
436
SEE ALSO GENETICS, GENETIC REGULATION. GENETIC
INDUCTION-REPRESSIONDEREPRESSION,
TRANSLATION
SEE ALSO HEMOPROTEINS BIOSYNTHESIS
SEE ALSO IMMUNOLOGY, ANTIBODY FORMATION
SEE ALSO NUCLEIC ACIDS, MRNA
SEE ALSO NUCLEIC ACIDS. TRNA
ROlHL-01803-23 0017 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Contractile and relaxing proteins of blood
vessels and platelets (mammals, human)
ROlHL-02262-23 Mechanisms regulating plasma proteins
and solutes (human, dogs)
ROlHL-02751-21 Function and metabolism of serum
albumin (mammals, fish, amphibians)
ROlHL-02986-21 Zonal renal change with potassium
deficiency (rats, human)
POlHL-031 74-23 0005 Mechanisms of acute vascular
reaction to injury - Renal small vessel dIdease-Cell and
matrix response (human, mice)
POlHL-0628518 0186 Cardiovascular-respiratory
physiology and biochemistry - Leukocyte hormone receptors
and cyclic nucleotides (tissue culture)
POlHL-06285-18 0193 Cardiovascular-respiratory
physiology and biochemistry • Hormonal regulation of
sodium transport -Aldosterone (rats, toads)
POlHL-063 14-17 0053 Immunologic mechanisms in
cardiovascular disease Cellular functions controlled by
cyclic GMP (human, mice, guinea pigs)
POlHL-063 14-17 0064 Immunologic mechanisms in
cardiovascular disease - Diabetic vascular disease (human,
rats, mice)
P01HL06835-17 0038 Cardiovascular disease - Effect of
chronic administration of angiotensin antagonist (rats)
POlHL-06835-17 0062 Cardiovascular disease - Role of
collagen in atherosclerosis (dogs, pigeons)
POlHL-09011-15 A research and resource program in
blood
* P01HL090 1115 0002 A research and resource program
in blood - Biosynthesis of fibrinogen (dogs)
* POlHL-0901115 0009 A research and resource program
in blood - Control of RNA synthesis in nucleated cells
(yeast, ascites cell)
■ POlHL-09011-15 0015 A research and resource program
in blood ' Regulation of synthesis and transport of diverse
proteins in liver (rats)
P01HL09011-15 0021 A research and resource program
In blood ■ Regulation of transfer RNA methylating enzymes
(rats, E coll)
' ROlHL-09172-15 Protem and RNA synthesis in heart
muscle (rats)
* R01HL09562-14 Cardiac protein synthesis, overload,
alcohol and anoxia (guinea pigs)
' ROlHL-1001811 Effect of aging on beating heart cells in
culture (rats)
P01HL1131012 0101 Mechanisms of cardiovascular
disease - Molecular pathogenesis of vascular disease
POIHLI 13 10-12 0105 Mechanisms of cardiovascular
disease - Biosynthesis of mammalian glycoproteins
(rabbits)
POlHL-11310-12 0106 Mechanisms of cardiovascular
disease - Biochemical characterization of the collagens in
vascular tissue (catte)
POlHL-l 1351-12 0004 Cellular and molecular
mechanisms of myocardial function - Molecular
mechanisms of contractile function and differentiation
(animals)
ROlHL-1 15 11-10 Structure of ferritin and its role in iron
metabolism (horse, rats, human)
R01HL11551-11 RNA and protein synthesis in repair of
heart injury (mice, rats)
ROlHL-12399-13 Specific fatty acids and cholesterol
metabolism (gerbils. rats)
ROlHL-12561-11 Cardiovascular studies on copper
deficiency (swine)
R01HL12972-09 Glutathione deficiency in red cells
(sheep, dogs)
POlHL-13262-07 0011 Arterial wall in atherosclerosis ■
Role of hypertension in atherosclerosis (human, monkey,
dog)
P01HL13262-07 0012 Arterial wall in atherosclerosis -
Characterization of connective tissue components (animals)
ROlHL-13831-08 Factors regulating embryonic cardiac
morphogenesis (chick, salamandra)
P50HL14164-07 0036 A/S SCOR -Comparative and
experimental atherosclerosis - Connective tissue
metabolism-Interaction with arterial metabolism (monkeys)
P50HL-14187-07 0012 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses - Vasoactive
mediators in pulmonary disease (human, animal)
P50HL-1419707 0005 Support for center of research on
arteriosclerosis - Lipoprotein biosynthesis and degradation
in vivo and in vitro (human, animal)
P50HL-142 12-07 0004 Correlated studies of pulmonary
fibrosis - Collagen metabolism in lung tissue and lung
cells (human, animal)
P50HL142 12-07 0007 Correlated studies of pulmonary
fibrosis ■ Protein metabolism in alveolar macrophages
(rabbits, guinea pigs, human)
P50HL-142 12-07 0016 Correlated studies of pulmonary
fibrosis - Role of pulmonary alveolar macrophages in
fibrosis (human, rabbit)
'Excludes routine methodology OR covers only general projects which preclude Indexing at the specific level.
**Onented significantly to above subject.
M Grant has subprojects describing specific research aspects
See Appendix for investigator's name and grant number.
PRO
P50HL-14214-07 0021 Newborn lung center for hyaline
membrane disease • Development of surfactant system-
Surfactant production and release (rat. rabbit)
* P50HL-14218-07 0006 Pulmonary SCOR-Newborn lung
center - Biochemical characteristics of the lung in ROS
(human, sheep)
* P50HL14237-07 0004 Support for arteriosclerosis center
- Synthesis, secretion of normal, abnormal plasma
lipoproteins (rodents, monkeys)
P01HL1438807 0190 Regulation of the circulation in
pathological states - Mechanisms of the renal actions of
aldosterone (rats)
ROlHL-1470607 Fetal hearts in organ culture (mice)
ROlHL-14847-07 Mechanism of action of vitamin K and
anticoagulants (rats)
R01HL1501307 Lung oxidative metabolism and energy
production (rodents, rabbits)
* ROIHL- 15026- 12 Quantitative genetic control of protein
synthesis (human, primates, mammals)
P50HL-15061-07 0004 Response of lung to injury -
Biochemical abnormalities in connective tissues (rats)
* P50HL-1506207 0009 Study of lipoproteins, artery wall.
and atherosclerosis - Plasma lipoprotein biosynthesis
(Rhesus monkeys)
P50HL15062 07 0020 Study of lipoproteins, artery wall,
and atherosclerosis ■ Artery wall reactions-Elevated
pressure and hyperlipemia (monkey)
* ROlHL-15478-05 Lipid flux and collagen synthesis in
atherosclerosis (rabbits)
* ROlHL-15619-05 Regulation of prothrombin synthesis in
cultured cells (rats)
POlHL-1583206 0001 Chemical-structural predispositions
to lung injury - Chemical composition of lung connective
tissue proteins (human, animals)
POIHL- 15835-06 0009 Study of muscles related to heart
disease Aspects of cardiac and skeletal myogenesis
(chick embryo)
R01HL15965-06 Experimental atherosclerosis and clastin
metabolism (chicks)
ROlHL-15985-06 Metabolic and hormonal control of
cardiac contraction
P60HL16005-05 0013 Comprehensive sickle cell center •
Study of regulation of erythropoiesis in vitro (human, rat,
hamster, rabbit)
P01HL16118-06 0005 Study of emphysema
Mechanisms of elastase emphysema (mice)
POlHL-16137-05 0004 Alveolar biology • Subcellular
processes and controls in the surfactant system (animals)
' POlHL-1613705 0008 Alveolar biology - Macromolecular
events in pulmonary cells m toxic environments (animals)
P01HL1625106 0004 Membrane-bound enzymes in heart
and other tissues • Biosynthesis and degradation of
succinate dehydrogenase, histidyl (yeast, mammal)
R01HL16364-04 Regulation of lipid biosynthesis and
transport (rats, swine, Xenopus)
P01HL16411-04 0003 Blood systems in coagulation and
vessel disease - Molecular events involving the late stages
of coagulation (rabbits)
ROlHL-16512-04 Lipoprotein metabolism and hormonal
regulation (chickens)
ROlHL-16588-05 Collagen synthesis in atherosclerosis
(dogs, rats, rabbits, human)
R01HL16633-04 Chemistry and biology of factor IX
activator (human, mice, rats)
ROlHL-16637-04 Development and regression of cardiac
hypertrophy (rats)
ROlHL-16725-03 Physiological regulation of pulmonary
surfactant (dogs, rats)
ROlHL-16768-04 The sympathetic nervous system and the
arterial wall (rabbits, pigeons)
ROlHL-16872-04 Antihemophilic factor (human)
ROlHL-16904-03 Regulation of smooth muscle cells in
arteriosclerosis (rabbit aorta)
P60HL-1 7269-04 0013 National heart and blood vessel
research and demonstration center - Peptide synthesis
laboratory (human)
P60HL-17269-04 0020 National heart and blood vessel
research and demonstration center - Nucleic acid and
protein metabolism in grovrth and development of heart
(rat)
POlHL-17419-04 Studies on mechanisms of hemostasis
POlHL-1741904 0006 Studies on mechanisms of
hemostasis - Effect of hormones, drugs and other agents
on fibrinogen synthesis (chick)
ROlHL-17551-04 Biosynthesis and metabolism of
procollagen (human, monkeys, mice)
P50HL17648-04 0025 Study of ischemic heart disease -
Destruction and repair of cardiac muscle cell constituents
(rat)
P50HL-17648-04 0026 Study of ischemic heart disease -
Control of muscle cell proliferation (organ culture)
P50HL-17665-04 0029 Study of ischemic heart disease -
Myocardial protein synthesis and degradation in low oxygen
states (rabbit, dog)
R01HL-177I0-04 Selective replication of hemoglobin genes
(mice, ducks, human)
POlHL-17812-04 0002 Thrombosis and plasma protems •
Activators of fibrinolysis-Synthesis and degradation
(human, cattle)
ROlHL-17882-04 Regulation of HMG-COA reductase and
sterol synthesis (human, mammals)
(contd)
PRO
ROIHI 18087 03 Development and rejression ol cefdiac
hypertrophy (ratsi rabbits)
PbOHL 1831803 OOlb Pathogenesis and comphcations ol
hypertension Cultured smooth muscle cells and
microvessel metabolism (mammals)
ROIHL 18634 03 Quarternary structure of erythro and
chlorocruorins (invertebrates)
POIHL 18645 03 0003 Biology o( the artery wall and
atherosclerosis Synthesis ol connective tissue proteins by
smooth muscle cells (human, monkeys)
POIHL 1870803 0007 Oxygen, energy and contractility in
cardiac tissue Surfaces, energy requirements, and
contractile proteins of cardiac cell in vitro
P01HL18708 03 0008 Oxygen, energy and contractility in
cardiac tissue Cardiac cell culture tacility
ROIHL- 187 1103 Electrophysiology of heart cells (rats,
chicks)
P50H11882803 0001 Specialized center of research in
thrombosis Membrane biology and hemostasis (human)
P50HL 1882803 0006 Specialized center of research in
thrombosis Etiology and pathogenesis of atherosclerosis
(rabbit, monkey, rat. human)
P50HL 1882803 0009 Specialized center of research in
thrombosis Platelet formation and megakaryocyte cell
biology (guinea pig, human)
' ROlHL-18876-03 Human alpha! antitrypsin synthesis in
vitro
R01HL1901003 Metabolism and cell biology of lung
surlactant system (rabbits, sheep)
R01HL1901103 Smooth muscle cell membrane
glycoprotein biosynthesis (cattle)
ROlHL-19056-03 Blood triglycerides and lipoprotein lipase
in the lung (rats)
ROlHL-19068-03 Changes m membrane properties during
erythropoiesis (chick embryo)
ROIHL 1907701 Biochemistry and molecular biology of
sarcoidosis (human, rabbits)
* R01HL1916803 Biosynthesis of plasma lipoprotein (rats.
rabbits)
P50HL-19171-02 0010 Pulmonary SCOR-Lung injury by
childhood infections - Metabolic pathways of normal and
injured respiratory cells
* P50HL-19185-02 0001 Pulmonary SCOR -Neonatal
respiratory distress syndromes Sites of synthesis,
secretion and structure of surface active material (rat)
P50HL19185-02 0002 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Biochemistry,
ullrastructure-Pulmonary surface active material (human,
animal)
* P50HL-19190-02 0004 Pulmonary SCOR-Pathophysiology,
management of IRDS - Type II cells-Control of protein
turnover (rabbit)
ROlHL-19195-03 Hormonal regulation of lung function
(rats)
* P01HL19242-02 0001 Study of vascular smooth muscle •
Energy metabolism and protein turnover in vascular smooth
muscle (rats)
POlHL-19242-02 0004 Study of vascular smooth muscle ■
Cyclic nucleotide metabolism in smooth muscle cultures
(human, rats)
ROlHL-19252-02 Vascular connective tissue -Role in
atherosclerosis (rabbits)
'* ROlHL-19322-03 Role of pituitary hormones in the action
of vitamin K (rats)
ROlHL-19459-03 Dynamics of atherogenesis and
lipoprotein formation (human, rabbit)
ROlHL-19491-03 Mechanism of iron storage and
mobilization by ferritin (horse)
R23HL-1959401 Tropocollagen and tropoelastin uptake in
lung cells (human)
ROlHL-19668-03 Biochemistry of lung connective tissue
(rats)
ROlHL-19673-03 Surgical aspects of shock and hypoxia
(dogs, monkeys, rats)
** P01HL19717-02 0001 Response of the lung to injury ■
Lung elastic tissue (animals)
'* POlHL-19717-02 0002 Response of the lung to injury -
Prolyl hydroxylase, lysyl hydroxylase and lung collagen
biosynthesis (rabbits)
POlHL-19717-02 0004 Response of the lung to injury -
Regulatory and physical-chemical properties of lung lysyl
oxidase (animals)
POlHL-19717-02 0006 Response of the lung to injury ■
Glycosaminoglycans and proteoglycans of the lung (human,
rats, hamsters)
POlHL-19717-02 0028 Response of the lung to injury -
Compensatory growth of the lung following pneumonectomy
(rabbits)
ROlHL-20087-02 Developmental processes in pulmonary
hypertension (rats)
ROlHL-20176-02 Biochemistry and genetics of salt
hypertension (rats)
ROlHL-20190-02 Pathogenesis of cardiac hypertrophy
Genetics of glycosyltransferases in
(dogs)
ROlHL-20301-02
human blood
ROlHL-20317-02 Procoagulant lipoproteins-Biochemistry
and bioactivity (goats, rabbits)
ROlHL-20344-02 Regulation of protein turnover in lung
tissue (rats)
ROlHL-20366-03 Protein turnover and amino acid
transport by lung (rats)
437
ROIHL 20384 09 Social stimulation. RNA and
cardiovascular disease (animals)
ROIHL 20388 03 Regulation of protein turnover in diabetic
heart (rat)
ROIHI 20547 02 Glycoproteins in pulmonary alveolar
proteinosis (human)
The development and regression of
Biochemical events in cardiac
PRO
ROIHI 21988 01
chnmotaxn
Biochemistry ol human plattld
POIHL 20552 02 0001
cardiac hypertrophy
hypertrophy (rats)
POIHL 20552 02 0010
cardiac hypertrophy
The development and regression of
Energy metabolism in the
hypertrophied heart animals
ROIHL 20577 03 The mechanism of action of vitamin K
POIHL 20592 02 0011 Cell biology of cardiac and
skeletal muscle Myosin and cytochrome oxidase
messenger RNAs (chicken)
ROIHL 20635 03 Factors in lung development (rat and
chick embryo)
ROlHL-20708-02 Voltage clamp of embryonic heart cell
aggregates (rat and chick embryos)
ROlHL-20764-02 Elastin and calcification in pulmonary
and vascular disease (human, mammals)
P01HL20984 02 0001 Cellular mechanisms in cardiac
hypertrophy Contractile proteins in cardiac hypertrophy
(rabbits, calves)
POIHL 20984-02 0005 Cellular mechanisms in cardiac
hypertrophy Neurohumoral receptors in cardiac growth
and compensatory hypertrophy (animals)
P50HL-2 1006-02 0003 Specialized center of research m
arteriosclerosis Transport of vitamin A in plasma (human,
The regulation of cardiac hypertrophy
Collagen synthesis by cultured human
rat)
* R23HL-2123402
(rabbits)
* ROlHL-2130302
vascular cells
ROlHL-2 1329-02 Beta-receptor regulation and cardiac
sites of drug action (cat, guinea pig, rat)
'* R23HL-2 1369-02 Tracheal mucin synthesis in experimental
bronchitis (rats)
R23HL-21396-02 Isolation, growth and metabolism of type
1 pneumocytes (rabbits)
R23HL-21504-02 Collagen synthesis in pulmonary fibrosis
cells (human)
ROlHL-21543-02 Structure-function relation of blood
clotting proteins (rabbits)
ROlHL-21617-02 Biochemistry of lung proteoglycans
(rabbits, cattle)
•* ROlHL-21646-02 Biosynthesis of fractionated
proteoglycans of lung (rabbits)
** R23HL-2 1663-01 Regulation of collagen biosynthesis
(chick, embryo)
ROlHL-21665-01 Collagen polymorphism and arterial
structure (monkeys, guinea pigs)
R23HL-21950-01 Endothelial cell mechanisms in vascular
disease (human)
** ROlHL-21970-01 Myofibrillar assembly and breakdown in
cardiac muscle (rats)
ROlHL-21995-01
effects
ROlHL-22081-20
(human, cattle)
ROlHL-22208-02
disease (chickens, rabbits)
" ROlHL-22290-01
synthesis (mice)
ROlHL-22333-01
(rats)
** ROlHL-22354-01
metabolism (rats)
ROlHL-22444-01 Bronchial mucus production in organ
culture (human)
** POlHL-226 19-01 0007 Cellular mechanisms ot heart
failure - Regulation of contractile protein levels in heart
muscle (rats)
ROlHL-22623-01 Polyamines cellular mediators of
atherogenesis (human)
** ROlHL-2272901 Intracellular degradation of newly
synthesized collagen (human, chick, rabbit)
ROlHL-22896-01 Immediate metabolic fates of kinins and
angiotensins (rat, rabbit, guinea pig)
ROlHL-22981-17 Membrane-associated functions in
microorganisms (bacteria, protozoa)
ROlHL-23542-01 Pulmonary vascular smooth muscle cell
dynamics (rat, rabbit)
R01HL-23626-01 A study of the regulation of myocardial
hypertrophy (rats)
NOlHV-42984-05 Interactions of modified biopolymers with
blood (humans, rats)
NOlHV-53029-04 Nonhuman primate models of
atherosclerosis
NOlHV-53030-05 Nonhuman primate models of
atherosclerosis and hypertension
NOlHV-53031-04 Nonhuman primate models of
atherosclerosis and hypertension
PROTEINS COAGULATION
SEE ALSO BLOOD COAGULATION
SEE ALSO PROTEINS DENATURATION
P60HL-151 57-07 0018 Comprehensive center for sickle
cell disease - Red blood cell membrane physiology in sickle
cell anemia (human)
P60HL-I5168-07 0009 Comprehensive sickle cell disease
center - Spin-label study of sickling (human)
Protein phosphorylation and adrenergic
The mechanism of collagen formation
Elastin structure, fibrogenesis and
., rabbits)
Cardiac energy metabolism and protein
Cellular basis of small airways function
Alpha-adrenergic effects on heart
PROTEINS CONTRACTION
Sf( AIS0MIJ<,C1I IIJNCIION. MIIV.Il (.ONIHAf.llON
•• ROlHt 01803 23 001/ ArterioscleroM-., glomerulonephritn.
rheumatic fever Contractile and relaxing proteins of blood
vessels and platelets (mammals, human)
ROIHI 09234 13 Ammo acids of conliactile proteins of
failing hearts (dogs, hamsters)
•• ROIHI 09544 12
(animals)
ROIHI 14938 06
(dogs, rabbits)
ROIHL 15679 06
Biochemistry of contractile proteins
Contractile proteins ol heart muscle
Heart and smooth muscle contractile
protein (swine, cattle, rabbits, chickens)
ROIHL 16010 16 Cellular basis of cardiac contractility
(frogs)
** ROIHL 1803004 The role of contractile proteins in
platelets (human, rabbits)
ROIHL 18077 04 Smooth muscle cell organization and
Ca20 concentration control (chickens)
•* ROIHL 1851603 Atherosclerosis and the arterial
contractile proteins (pigs, rabbits)
POIHL 1857503 0001 Mechanisms of vascular changes
in hypertension Arteries and resistance vessels in
hypertension (pigs, rats)
ROIHL 1866003 Neurotransmitter receptors in human
erythrocytes
•* POIHL 18708 03 0007 Oxygen, energy and contractility in
cardiac tissue Surfaces, energy requirements, and
contractile proteins of cardiac cell in vitro
POIHL 18708 03 0008 Oxygen, energy and contractility in
cardiac tissue Card'ac cell culture facility
** ROIHL 19323-03 Studies of platelet microtubule protein
*' ROIHL 19429-03 Phagocytosis- Ingestion in alveiolar
macrophages (rabbits)
R01HL2075402 Anesthetic-induced myocardial depression
(rabbits)
ROlHL-21096-02 Sickle cell crisis -Role of the erythrocyte
membrane (human)
** ROlHL-21471-02 Structure-function studies on actin and
myosin (human, protozoa, rabbits, cattle)
ROlHL-21993-01 Hypertensive hypertrophy -Effects of
cardiac mechanics (rats)
ROlHL-22137-02 Structure-function pathology of isolated
heart ceils (mice, rats)
•* ROlHL-22194 02 Allosteric function of platelet contractile
proteins (human)
ROlHL-23990-01 Role of phosphoprotein in cardiac
inotropic responses
PROTEINS DENATURATION
SEE ALSO PROTEINS COAGULATION
ROlHL-13652-08 Metal sites in metalloproteins
(mushroom)
P50HL 15062-07 0007 Study of lipoproteins, artery wall.
and atherosclerosis - Physical chemistry of lipidprotein
interaction (human)
ROlHL-16637-04 Development and regression of cardiac
hypertrophy (rats)
** R23HL-21271-02 Extracorporeal circulation and protein
denaturation (human)
ROlHL-21622-02 Structure and interactions of lung
proteoglycans (cattle)
PROTEINS METABOLISM
SEE ALSO AMINO ACIDS METABOLISM (GENERAL)
SEE ALSO HEMOPROTEINS METABOLISM
SEE ALSO PROTEINS BIOSYNTHESIS
" ROlHL-02751-21 Function and metabolism of serum
albumin (mammals, fish, amphibians)
" POlHL-06285-18 0203 Cardiovascular-respiratory
physiology and biochemistry - Pathways of lipid transport
in the blood (animals)
POlHL-0629618 0005 Cardiovascular and pulmonary
adaptation to stress - Regulation of ventricular
performance (animals)
POlHL-0666417 0036 Cardiopulmonary function in
remediable vascular disease - In vitro studies on the
mechanism of ischemic damage to cells (rabbits)
ROlHL-09172-15 Protein and RNA synthesis in heart
muscle (rats)
ROlHL-09744-14 Experimental vascular sclerosis
(monkeys, rabbits)
POlHL-11310-12 0080 Mechanisms of cardiovascular
disease • Metabolism of the hypertrophied myocardium
(human)
POlHL-13262-07 0015 Arterial wall in atherosclerosis -
Crosslinkage biosynthesis in aortic elastin and collagen
(animals)
** P50HL-14147-08 0006 Specialized center of research in
thrombosis ■ Clearance mechanisms of coagulation
moieties (human, rabbits, rodents)
P50HL-14187-07 0014 Pulmonary SCOR -Chemical
mediators in pulmonary vascular responses - Metabolism
and actions of vasoactive peptides in lung (human,
mammals)
M P50HL-14197-07 Support for center of research on
arteriosclerosis
** P50HL-14197-07 0005 Support for center of research on
arteriosclerosis - Lipoprotein biosynthesis and degradation
in VIVO and in vitro (human, animal)
(contd)
•Excludes routine methodology OR covers only general projects which preclude
"Oriented significantly to above subiect.
indexing at the specific level.
M Grant has subprojeds describing specific research aspects.
See Appendix for investigator's name and grant number.
PRO
** P50HL14197-07 0007 Support for center of research on
arteriosclerosis • Metabolic defects in familial
fiyperlipoproteinemias (human)
** P50HL14212-07 0004 Correlated studies of pulmonary
fibrosis - Collagen metabolism in lung tissue and lung
cells (human, animal)
** P50HL14212-07 0007 Correlated studies of pulmonary
fibrosis - Protein metabolism in alveolar macrophages
(rabbits, guinea pigs, human)
P50HL-1421207 0016 Correlated studies of pulmonary
fibrosis ■ Role of pulmonary alveolar macrophages in
fibrosis (human, rabbit)
P50HL-1421807 0004 Pulmonary SCOR -Newborn lung
center - Metabolism of infants with respiratory distress
syndrome (human)
P50HL14237-07 0001 Support for arteriosclerosis center
- Role of apolipoproteins in lipoprotein catabolism (human.
rats)
** R01HL14313-07 Apoproteins of triglyceride rich
lipoproteins (human, squirrel monkeys, rats)
" P50HL-15062 07 0009 Study of lipoprotems. artery wall,
and atherosclerosis - Plasma lipoprotein biosynthesis
(Rhesus monkeys)
P50HL 15062-07 0019 Study of lipoproteins, artery wall,
and atherosclerosis - Factors regulating lipoprotein-smooth
muscle cell interaction (monkey)
ROIHL- 15448-06 Surgical and metabolic aspects of
venous grafts, (dogs, monkeys, rabbits)
** ROlHL-15965-06 Experimental atherosclerosis and elastin
metabolism (chicks)
ROIHL 16166-05 Structure of alpha-1-antitrypsin in
relation to emphysema (human)
ROIHL 16512-04 Lipoprotein metabolism and hormonal
regulation (chickens)
** ROlHL-16637-04 Development and regression of cardiac
hypertrophy (rats)
" P60HL 17269-04 0015 National heart and blood vessel
research and demonstration center ■ Lipoprotein
metabolism laboratory (human)
ROIHL 17551-04 Biosynthesis and metabolism of
procollagen (human, monkeys, mice)
P5GHL 17648-04 0025 Study of ischemic heart disease -
Destruction and repair of cardiac muscle cell constituents
(rat)
** P50HL-1 7665-04 0029 Study of ischemic heart disease -
Myocardial protein synthesis and degradation in low oxygen
states (rabbit, dog)
** ROlHL-18258-04 Regulation of protein degradation in
heart (rats)
P50HL 18318-03 0014 Pathogenesis and complications of
hypertension - Arterial metabolism and atherogenesis (rat,
rabbit)
ROlHL-18824-03 Mechanisms of heart failure in
myopathic hamster
ROlHL-18918-03 Characterization of lung elastins (rat,
rabbit, chicken. Rhesus)
ROlHL-19063-03 Cholesterol and lipoprotein metabolism
(rat hepatocytes)
P50HL-191 53-02 0002 SCOR -Pulmonary edemas -Eitology,
pathogenesis - Lung fluid dynamics -Classical mediators
and their inhibitors (sheep)
P50HL-19153-02 0003 SCOR -Pulmonary edemas-Eitology.
pathogenesis - Possible inhibitors of mediator release and
pulmonary vascular response (sheep)
ROlHL-19173-03 Analysis of blood trauma from
microporous oxygenators (human, dogs, rabbits)
** P50HL-19190-02 0004 Pulmonary SCOR-Pathophysiology,
management of IRDS - Type II cells -Control of protein
turnover (rabbit)
ROlHL-19252-02 Vascular connective tissue-Role in
atherosclerosis (rabbits)
R01HL-ig419-03 Cellular interactions with foreign
materials (mammals)
** ROIHL'20388'03 Regulation of protein turnover in diabetic
heart (rat)
" R01HL20391-03 Polydisperse LDL-Structure, metabolism
and function (human)
ROlHL-20397-03 VLDL-TG metabolism in diabetes mellitis
(human, rat)
ROlHL-20447-03 Connective tissue and diabetic vascular
disease (human)
** ROlHL-21001-01 Protein and thrombus deposition on
vascular grafts
ROlHL-21096-02 Sickle cell crisis-Role of the erythrocyte
membrane (human)
** ROlHL-21 140-01 Studies of pulmonay alveolar
macrophage function (rabbits)
R23HL-2122502 Connective tissue precursor molecules in
the lung (rabbits, hamsters)
ROlHL-21641-02 Structural studies of lung proteoglycans
(pigs, cattle, rabbits)
** ROlHL-21644'01 Fibronectin and related glycoproteins
(human, rodents)
** R23HL-22383-01 Biosynthesis-Response to oxygen
depletion (human, primates, rats)
ROlHL-22486-01 Enzyme regulation in cultured arterial
cells (swine)
R01HL'22S52-02 Abnormal alveolar permeability and lung
disease (sheep)
POlHL-22619-01 0010 Cillultr mechanisms of heart
failure • MItochondrIi In heart ind smooth muscle (rabbits,
rits, dogs)
438
** ROlHL-22651-01 Control of protein metabolism in heart
muscle
N01HV-72978-02 Development of models of hypertension
N01HV-72980-02 Development of models of hypertension
PROTEINS METABOUSM DISORDERS
SEE ALSO BLOOD PROTEINS DISORDERS
SEE ALSO BLOOD PROTEINS DISORDERS CONGENITAL
SEE ALSO METABOLIC DISORDERS (INBORN), AMYLOIDOSIS
** ROlHL-12085-10 Lipoprotein-carbohydrate metabolism
(human, rats)
ROlHL-16588-05 Collagen synthesis in atherosclerosis
(dogs, rats, rabbits, human)
ROlHL-20954-02 Hypertipoproteinemia (rats, human)
PROTEINS METABOLISM DISORDERS,
PROTEINOSIS
SEE ALSO RESPIRATORY DISORDERS. PULMONARY ALVEOLAR
PROTEINOSIS
P01HL-078g6-15 0021 Environmental biomedical research
program - Liquid breathing and lung lavage (human)
ROIHL 11907-08 Mechanisms of physiological responses
to exercise (human, dogs)
ROlHL-20675-02 Alveolar macrophage function in man
PROTEINS-PEPTIDES STRUCTURE
SEE ALSO ENZYME STRUCTURE
SEE ALSO GLOBULINS, GAMMA GLOBULINS,
IMMUNOGLOBULIN STRUCTURE
SEE ALSO HEMOPROTEINS STRUCTURE
R01HL01662-25 Equilibria in the fibrinogen-fibrin
conversion (human, cattle)
R01HL-0I803-23 0001 Arteriosclerosis, glomerulonephritis.
rheumatic fever - Poststreptococcal glomerulonephritis
(rabbit)
ROlHL-02942-22 Biochemistry of cardiovascular connective
tissue (human, cattle, primates)
** ROlHL-02965-22 Metabolism of plasma lipoproteins (rats,
chickens, human)
** ROlHL-04366-19 Plasminogen -Activation and structure-
function relations (mammals, birds)
** ROlHL-06221-17 Composition and structure of plasma
lipoproteins (human, turkeys, baboons)
POlHL-06285-18 0173 Cardiovascular-respiratory
physiology and biochemistry - Skeletal and cardiac muscle
function
POlHL-06285-18 0215 Cardiovascular-respiratory
physiology and biochemistry - Conformation of biopolymers
** POlHL-063 14-17 0051 Immunologic mechanisms in
cardiovascular disease - Conformational studies of
phospholipid membranes and proteins
R01HL08893-14 Structure and function of membrane
proteins (human)
POlHL-09011-15 0005 A research and resource program
in blood - Characterization of hepatitis-B antigen and the
cause of serum hepatitis (human)
ROlHL-09489-13 Myocardial lipid metabolism and
regulation (rats)
ROlHL-09544-12 Biochemistry of contractile proteins
(animals)
ROlHL-09739-13 Biophysical studies of proteins (human)
ROlHL-10018-11 Effect of aging on beating heart cells in
culture (rats)
** ROlHL-103 16-13 Structural studies on low density serum
lipoproteins (human)
ROlHL-10642-18 Plasma cholesterol metabolism (human,
macaca)
POIHLI 13 10-12 0096 Mechanisms of cardiovascular
disease - Complement chemistry and biology (human,
rabbits)
POlHL-11310-12 0097 Mechanisms of cardiovascular
disease - Structural-functional relationships of neuronal
differential alloantigens (mice)
POlHL-l 13 10-12 0100 Mechanisms of cardiovascular
disease - Structure and replication of arenavirus and
Bunyamweraviruses
POlHL-l 13 10-12 0101 Mechanisms of cardiovascular
disease - Molecular pathogenesis of vascular disease
ROlHL-11511-10 Structure of ferritin and its role in iron
metabolism (horse, rats, human)
** ROlHL-11822-10 Biophysical studies of macromolecular
interactions (microorganism, human)
R01HL-12561-1I Cardiovascular studies on copper
deficiency (swine)
POlHL-13262-07 0011 Arterial wall in atherosclerosis -
Role of hypertension in atherosclerosis (human, monkey,
dog)
POlHL-13262-07 0012 Arterial wall in atherosclerosis -
Characterization of connective tissue components (animals)
P01HL13262-07 0015 Arterial wall in atherosclerosis -
Crosslinkage biosynthesis in aortic elastin and collagen
(animals)
ROlHL-13831-08 Factors regulating embryonic cardiac
morphogenesis (chick, salamandra)
ROlHL'13909-27 Physlochemistry and Immunology of
macromolecules
** ROlHL-13989-05 Role of water In resplratiory protein
structure
** ROlHL'14020-06 Characterization of myosin from blood
platelets (rabbit)
** P50HL-14147-08 0018 Specialized canter of research In
thrombosis ■ Biochemical aspects of platelet function In
thrombosis and cell growth (human)
PRO
P50HL-14153-07 0016 Johns Hopkins Lung Center-
Chronic diseases of airways - Airways defense mechanisms
(dogs)
P50HL-14217-08 0048 Specialized center of research In
thrombosis - Fibrinolysis section-Structural studies (human,
animal)
P50HL 14217-08 0062 Specialized center of research in
thrombosis - Coagulation section-Factor VIII and Factor XII
(human, cattle)
P50HL 14230-07 0098 A/S SCOR -Lipids, atherosclerosis
and thrombosis Molecular properties of factor VIII (cattle,
human, mice)
P50HL-14237-07 0001 Support for arteriosclerosis center
- Role of apolipoproteins in lipoprotein catabolism (human,
rats)
P50HL-14237-07 0003 Support for arteriosclerosis center
- Structure of lipoproteins and apolipoproteins (human,
rabbits)
ROlHL-14313-07 Apoproteins of triglyceride rich
lipoproteins (human, squirrel monkeys, rats)
ROlHL-14483-08 Energy conservation in heart
mitochondria (cattle, E coll. human)
ROlHL-14509-07 Hypertension-Chemistry and biophysics
of angiotensin
ROIHL 14938-06 Contractile proteins of heart muscle
(dogs, rabbits)
P50HL-15062-07 0001 Study of lipoproteins, artery wall.
and atherosclerosis Structure and molecular interactions
of serum lipoproteins (human, monkey)
P50HL- 15062-07 0007 Study of lipoproteins, artery wall.
and atherosclerosis - Physical chemistry of llpid-protein
interaction (human)
P50HL 15062-07 0009 Study of lipoproteins, artery wall.
and atherosclerosis - Plasma lipoprotein biosynthesis
(Rhesus monkeys)
P50HL 15062-07 0013 Study of lipoproteins, artery wall,
and atherosclerosis Radioimmunoassay of apolipoproteins
(human, monkeys)
P60HL-15157-07 0009 Comprehensive center for sickle
cell disease Red cell membrane alterations during
sickling (human)
P60HL-15157-07 0011 Comprehensive center for sickle
cell disease - Development of specific antisickling
compound (human)
P60HL-1515707 0018 Comprehensive center for sickle
cell disease - Red blood cell membrane physiology in sickle
cell anemia (human)
ROlHL-15308-07 Assays for peptides of lipoproteins
(human)
ROlHL-15427-06 Secretion of plasma lipoproteins (rats)
ROlHL-15535-06 Structure and function of human plasmin
P01HL-15596-05 0002 Coagulation, fibrinolysis,
hemostasis and hepatitis - Radioimmunoassay of
fibrinogen and fibrin derivatives (human)
ROlHL-15679-06 Heart and smooth muscle contractile
protein (swine, cattle, rabbits, chickens)
ROlHL-15793-06 Molecular aspects of erythrocyte
membrane resealing (human)
ROlHL-15797-05 Lipid metabolism and atherosclerosis In
primates (monkeys, human, squirrels)
ROlHL-15799-04 Effect of anesthetics on myocardial
function (cats)
POlHL-15835-06 0001 Study of muscles related to heart
disease - Control of contraction-relaxation of heart and
muscle (rabbits, chickens)
POlHL-15835-06 0006 Study of muscles related to heart
disease - UKrastructural and chemical studies of muscle
(animals)
ROlHL-15887-05 Enzymes of blood coagulation and
fibrinolysis (human)
ROlHL-1595806 X-ray diffraction analysis of thrombin
and neurotoxin
ROlHL-15965-06 Experimental atherosclerosis and elastin
metabolism (chicks)
P60HL-1600S-05 0013 Comprehensive sickle cell center -
Study of regulation of erythropoiesis in vitro (human, rat,
hamster, rabbit)
ROlHL-16059-06 Structure and function of serum
lipoproteins (cattle, human)
ROIHL 16087-05 Structural and dynamic study of model
heme complexes (yeast)
ROlHL-16093'05 Functional properties of hemoglobin and
erythrocytes
POlHL-16607-05 0005 Calcium ion and control of
cardiovascular function - Chemical modifications of tlte
sarcoplasmic reticulum membranes (rabbits)
ROlHL-16678-03 Fluorescent probe studies of heart
muscle proteins (rabbit, dog)
R01HL-16891-0S The folding of hemoglobin
ROlHL-17194-03 Comparison of two inherited forms of
alpha-l-antltrypsin (human)
P60HL-17265-04 0002 Community blood resource center
support - Research-Human factor VIII
P60HL-17265-04 0003 Community blood resource center
support ■ Research-Human factor IX-Rola in intrinsic
clotting (also baboons, dogs)
P60HL- 17269-04 0001 National heart and blood vessel
research and demonstration center ■ Atharosclarosls-
Arterial pathology and plasma lipids (human)
P60HL-17269-04 0013 National heart and blood vassal
research and demonstration center ■ Peptide synthasii
laboratory (human)
'Exdudat nutlne m«thodok)|y OR covers only ginerti projects which preclude Indexing at the specific level.
"Oriented slinlflcintly to above subitct. ,
M Grant has subpnjjects describing specific research aspects.
Sea Appendix for investigator's name and grant number.
PIO
ROIHL I Mil 04 MoIkuIii studies ol fad blood call
sp«cUln diumin)
POIHI 1741904 Studias on machanisms of hemostasis
POIHL 1M19 04 0001 Studias on machanisms of
hamostasis Structute and matabolism ot librinogan
(human)
POIHI 1741904 0006 Studias on mechanisms ol
hamostasis Etiact ol hormones, drugs and other agents
on fibrinogen synthesis (chick)
POlttl 1741904 0007 Studies on mechanisms ot
hamostasis Structural analysis of ordered forms ot
fibrinogen (human, cattle)
ROIHL'1746303 Composition and structure ot plasma
lipoproteins (human, rabbits)
ROIHL 1749407 Mechanism of liqand binding to
hemoglobin (human)
R01HL'17S2S'03 Molecular basis of collagen platelet
interaction (human, rat)
R01HL'175S104 Biosynthesis and metabolism of
procollagen (human, monkeys, mice)
PSOHl 1766S'04 0011 Study of ischemic heart disease -
Development ol new methods for the determination of
infarct siie (dog. human)
ROlHl-1778304 Complex carbohydrates-Structure.
function, synthesis (swine)
ROIHLI 7828-04 Kinetic studies of hemerythrin reactions
(marine worms)
ROIHI'17882'04 Regulation of HMGCOA reductase and
sterol synthesis (human, mammals)
ROIHL 1789603 Dehydropeptide renin substrates
ROIHL'17898'03 Cell membranes and plasma lipoproteins
(human, swine)
ROIHL'1799504 Cellular synthesis and release of
mucopolysaccharides (rabbits)
R01HL'18I79-03 Heart, platelet, and muscle myosins and
actomyosins (cattle)
ROlHL-18226-04 Mechanism of oxygen supply to tissue
(human, animals)
ROlHL'18527-03 Subcellular response of heart to
functional overload (hamsters, rats)
' ROlHL'18533-03 Microcrystalline and crystalline fibrinogen
(cattle, bacteria)
' ROlHL-18553-03 Membrane defects in familial
hypercholesteremia (human)
POlHL-18574-03 Lipoprotein methodology and biomedical
applications
POlHL-18574-03 0001 Lipoprotein methodology and
biomedical applications - Ultracentrifugal and
electrophoretic lipoprotein methodology-Applications
* POlHL-18574-03 0004 Lipoprotein methodology and
biomedical applications ■ Fine structure and metabolism of
lipoproteins -EM studies (guinea pigs)
* P01HL18574-03 0005 Lipoprotein methodology and
biomedical applications - Structure and function of
lipoproteins
* P01HL18577-03 0001 Lipoproteins-Cell surface
interactions ■ Structural studies of serum lipoproteins in
man and dogs
* ROlHL-18619-03 Transferrin iron binding and transport
properties (chicken, rabbit, human)
* ROlHL-18746-02 Chemical studies on proteolipid
apoproteins (cattle)
P50HL18828-03 0001 Specialized center of research in
thrombosis - Membrane biology and hemostasis (human)
P50HL-18828-03 0002 Specialized center of research in
thrombosis - Endothelial cell biology (human, guinea pig)
ROlHL-18918-03 Characterization of lung elastins (rat.
rabbit, chicken. Rhesus)
ROlHL-18931-02 Lung elastic tissue characteristics
(swine, human)
P50HL19157-02 0007 Studies in cystic fibrosis and
bronchiolitis - Analysis of cystic fibrosis factors (human)
P50HL-19160-02 0001 Mucus abnormality in cystic
fibrosis ■ Regulation of respiratory secretions (rat, human)
* P50HL19185-02 0002 Pulmonary SCOR-Neonatal
respiratory distress syndromes • Biochemistry,
ultrastnicture-Pulmonary surface active material (human,
animal)
P50HL-19187-02 0002 Pediatric pulmonary SCOR-Hyaline
membrane disease - Hyaline membrane disease-Alterations
in surface active material (monkeys)
P50HL-19187-02 0004 Pediatric pulmonary SCOR-Hyaline
membrane disease - Hyaline membrane disease-Surface
active material, lamellar bodies (mice, rats)
'* P50HL-19190-02 0005 Pulmonary SCOR-Pathophysiology,
management of IRDS - Glycoproteins in mucous secretions
(human, cattle)
R01HL19459-03 Dynamics of atherogenesis and
lipoprotein formation (human, rabbit)
" ROlHL-19481-03 High-field NMR studies of respiratory
proteins (human, horse, fish, microbes)
ROlHL-19488-03 Picosecond laser studies of heme-
proteins
ROlHL-19491-03 Mechanism of iron storage and
mobilization by ferritin (horse)
ROlHL-19767-01 Pathochemistry of fibrinogen (humans)
ROlHL-19982-02 Blood coagulation-Proteln-metal ion-llpid
Interactions
ROlHL-20092-02 Structural and biological properties of
fibrinogen (human, rabbits)
>* ROlHL-20114-02 Collagen-platelet Interaction and human
lortt colligan (human)
439
ROIHL 70300 02 Histone H5 and avian arythropoiesii
(chickens, rabbits)
ROIHL 2031702 Procoagulant lipoproteins- Biochamlsliy
and bioactivity (goats, rabbits)
ROIHL 203 19 02 Assembly, structure and Intaractlons of
fibrin (human)
ROIHL 20391 03 Polydisperse LDL Structure, metabolism
and function (human)
ROIHL 20464 01 Regulation ol cardiac and skeletal
muscle contraction (mammals)
ROlHL-20471 03 Atherosclerosis and diabetes mellitus
(human)
ROIHL 2051 703 Diabetes, somatotropin, factor )/lll and
atherosclerosis (human, animal)
ROIHL 2052003 Protein modification-The key to diabetic
se()uelae (human, animal)
ROlHL-20546 02 Chemical analysis of human arterial
elastin
ROIHL 20547-02 Glycoproteins in pulmonary alveolar
proteinosis (human)
ROlHL-20712 02 Characterization of the B proteins of
serum lipoproteins (human)
ROlHL-20882-02 Interactions of plasma lipoproteins with
erythrocytes (Rhesus, human)
Hyperlipoproteinemia (rats, human)
Molecular structure of human serum
Purification of renal renin (human)
Structure of factor Vlll-Von Willebrand
ROlHL-2095402
ROlHL-21170 01
transferrin
R23HL-21247-02
ROlHL-21379-01
protein (human)
R23HL-21413-02 Structure and function of platelet
calcium-binding protein (human)
R23HL-21504-02 Collagen synthesis in pulmonary fibrosis
cells (human)
ROlHL-21543-02 Structure-function relation of blood
clotting proteins (rabbits)
ROlHL-21592-01 Lipoproteins and coagulation factors In
atherosclerosis (pigeons)
ROlHL-21612-02
(human, rabbits)
ROlHL-21617-02
(rabbits, cattle)
ROlHL-21622-02 Structure and interactions of lung
proteoglycans (cattle)
ROlHL-21641-02 Structural studies of lung proteoglycans
(pigs, cattle, rabbits)
Biochemistry of lung proteoglycans
Biochemistry of lung proteoglycans
Fibronectin and related glycoproteins
Biochemistry of lung proteoglycans
Regulation of collagen biosynthesis
ROlHL-21644-01
(human, rodents)
ROlHL-21649-01
(mammals)
R23HL-21663-01
(chick, embryo)
R01HL-2166S-01 Collagen polymorphism and arterial
structure (monkeys, guinea pigs)
ROlHL-21676-02 Purification and properties of
erythropoietin (human)
ROlHL-21683-02 Purification of erythropoietin (human)
ROlHL-21686-02 Purification of erythropoietin (human)
ROlHL-21692-02 Purification of erythropoietin (human)
ROlHL-21701-02 Purification of erythropoietin (human)
ROlHL-21757-0! Elastin structure-DNA breathing-
Hemoglobin S gelation
ROlHL-21791-01 Precipitation of proteins with poly
(ethylene glycol) (human)
ROlHL-21845-01 Human red cell membrane-Structure and
function
ROlHL-22052-01 Organization of free cholesterol in serum
lipoproteins (human, dogs)
R01HL-22081-20 The mechanism of collagen formation
(human, cattle)
ROlHL-22194-02 Allosteric function of platelet contractile
proteins (human)
ROlHL-22208-02 Elastin structure, fibrogenesis and
disease (chickens, rabbits)
ROlHL-22355-01 Purification, structure and function of
factor VIII (human)
ROlHL-22461-01 Cardiac tropomyosin and tropomyosln-
action interactions (rabbit)
ROlHL-22471-01 Biochemistry of prothrombin quick
(human)
ROlHL-22583-02 Ultrastructural study of endothelium in
thrombosis (human)
ROlHL-22607-01 Role of apolipoprotein E In lipoprotein
metabolism (human)
POlHL-226 19-01 0005 Cellular mechanisms of heart
failure - Molecular mechanism of regulation of cardiac
muscle contraction (cattle)
' POlHL-226 19-01 0011 Cellular mechanisms of heart
failure - Reaction of lipoproteins and apolipoproteins with
lipoprotein lipase (cattle)
POlHL-226 19-01 0012 Cellular mechanisms of heart
failure - Apolipoproteins In hypertriglyceridemia (human)
' POlHL-226 19-01 9002 Cellular mechanisms of heart
failure - Medicinal chemistry and clinical intervention
ROlHL-22627-01 An Inhibitor of platelet adhesion to
artificial organs (human)
ROlHL-22654-01 Molecular structure of sickle cell fibers
(human)
ROlHL-22983-01 Studias on the catabolism of plasma
lipoproteins (rats)
* ROlHL-22985-01 Properties and assembly of Z-dlsk
proteins (human, other species)
PRO
** ROIHL 2323301 Pulmonary artery intermediate filament
structure (cattle)
*• ROIHI 23249 01 Actio myosin interaction in pulmonary
smooth muscle (cattle)
ROIHL 23994 01 Biochemical properties ol human cardiac
myosin
** NOIHR 72923 01 Cystic fibrosis factor identification and
quantification (human)
PROTEINS-PEPTIOES STRUCTURE, AMINO ACIDS
SEQUENCE
ROIHL 02212 23 Coagulation of blood (human)
R01HL02558-22 Structure function relationships in the
heme proteins (human, cattle)
ROIHL 02751-21 Function and metabolism of serum
albumin (mammals, fish, amphibians)
POIHL 03174 23 0002 Mechanisms of acute vascular
reaction to injury Chemical structure, pathological
significance of amyloid substance (human, mice)
ROlHL-05556 19 Proteins, lipoproteins Structure and
reactivity (chicken, human, diving mammals)
ROIHL 0594918 Biochemistry of muscle contraction (rats,
rabbits)
** POlHL-06350-17 0020 Hemostasis research program
project Structure and function of coagulant venom
proteases
ROIHL 07379-13 Structure and function of fibrinogen
(human)
" R01HL08299-16 Molecular biology of hemerythrin and
hemocyanin (invertebrates)
ROlHL-08399-15 Platelet injury in infections and allergic
diseases (human)
ROlHL-09234-13 Amino acids of contractile proteins of
failing hearts (dogs, hamsters)
R01HL10383-12 Physical-chemical studies of hemoglobins
and erythrocyte (human)
** POIHLI 1310-12 0098 Mechanisms of cardiovascular
disease - Protein chemistry of thy-1 and related
synaptosomal proteins (mice)
POlHL-11310-12 0099 Mechanisms of cardiovascular
disease - Carbohydrate chemistry of thy-1 and related
synaptosomal proteins
POlHL-l 1310-12 0104 Mechanisms of cardiovascular
disease - Structure of connective tissue proteoglycans
(rabbits)
POlHL-11310-12 0106 Mechanisms of cardiovascular
disease - Biochemical characterization of the collagens in
vascular tissue (catte)
POlHL-l 1351-12 0004 Cellular and molecular
mechanisms of myocardial function - Molecular
mechanisms of contractile function and differentiation
(animals)
** R01HL11963-10 Biochemistry of blood vessel formation
and disease (swine)
ROlHL-12585-10 Structural properties of malate
dehydrogenase (swine)
** ROlHL-13160-08 Human thrombin (also cattle)
P50HL-14153-07 0015 Johns Hopkins Lung Center-
Chronic diseases of airways - Kinins and human lung
P50HL-14187-07 0012 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses - Vasoactive
mediators in pulmonary disease (human, animal)
P50HL-14192-08 0004 Specialized center of research in
hypertension - Isolation and characterization of pure renin
(swine, rats, human, rabbits)
P50HL-14217-08 0054 Specialized center of research in
thrombosis - Coagulation section-Platelet aggregation
(human, pig, rabbit, dog)
P50HL- 142 18-07 0006 Pulmonary SCOR-Newborn lung
center - Biochemical characteristics of the lung in RDS
(human, sheep)
P50HL-14236-05 0008 Prevention of premature
arteriosclerosis - Lipoproteins of cell membranes (human)
P50HL-14237-07 0001 Support for arteriosclerosis center
- Role of apolipoproteins In lipoprotein catabolism (human,
rats)
P50HL-14237-07 0003 Support for arteriosclerosis center
- Structure of lipoproteins and apolipoproteins (human,
rabbits)
ROlHL-14262-07 Leukocyte proteases and their lung
targets (human, dogs, rabbits)
** ROlHL-14680-07 Specific enrichment of myoglobins for
carbon 13 NMR (catacea)
ROlHL-14778-10 Proteolytic enzymes and inhibitors in
lung disease (mammals, human)
ROlHL-14865-07 Biochemical studies on the pathogenesis
of emphysema (human, rats)
P50HL-15061-07 0004 Response of lung to injury -
Biochemical abnormalities in connective tissues (rats)
P50HL-1506207 0001 Study of lipoproteins, artery wall,
and atherosclerosis - Structure and molecular interactions
of serum lipoproteins (human, monkey)
ROlHL-15125-07 Molecular pathology of genetic disorders
In man
P60HL-15158-07 0014 Comprehensive sickle cell center -
Mechanism of sickling in human and deer hemoglobins
P60HL-15160-07 0008 Center for sickle cell disease -
Isocyanate derivatives and hemoglobin S association
(human, rat)
P60HL-15162-07 0017 Comprehensive sickle cell center -
Hemoglobin, erythrocytes and sickle cell anemia (human,
rabbit)
(contd)
'Cuekidm routine mathodokigy Oft coven only ganaral projacti which praclude Indexing at the ipaclfic laval.
"Ortantad ilgnlflcantly to ibovi lubjact.
M Grant hai lubprojectt describing specific research aspects.
Sm Appendix for Investigator's name and grant number.
PRO
440
PRO
Inhibitors of proteinases (human, cattle.
Primary structure of prothrombin (cattle,
P50HL15389-07 0014 Pulmonary SCOR-Hyperscnsitivity
pneumonitis Fractionation and characterization of pigeon
antigens
P50HL-15389-07 0015 Pulmonary SCOR-Hypersensitivity
pneumonitis - Fractionation and characterization of
thermophilic Actinomycete antigens
ROlHL-15391-07 EPR studies on rotational motion of
myosin and actin
ROlHL-15460-06 Molecular adaptation-Hemoglobin
systems of fish (marine)
ROlHL-15474-06 Structure and function of the
antihemophilic factor (human, cattle)
P01HL15486-06 0005 Studies on thrombosis - Isolation
and characterization of PF4 antigens (rabbits)
R01HL15535-06 Structure and function of human plasmin
P01HL15596-05 0008 Coagulation, fibrinolysis,
hemostasis and hepatitis - Structural studies and
fractionation of antihemophilic factor (human)
R01HL15615-06 Structure-function studies of human
factor VIII/vWF
POlHL-1583206 0009 Chemical-structural predispositions
to lung injury - Immunology-Enzyme degradation products
of human lung elastin and microfibril
POlHL-1583206 0010 Chemical-structural predispositions
to lung injury - Kinin generating systems in pulmonary
disease (human, animals)
ROlHL-15892-05
swine)
ROlHL-16150-05
human)
ROlHL-16166-05 Structure of alpha-1-antitrypsin in
relation to emphysema (human)
ROlHL-16233-05 f^olecular cardiology of MDP-induced left
ventricular failure (dogs)
ROlHL-16238-05 Protein structure in coagulation and
fibrinolysis (human)
POlHL-16251-06 0002 Membrane-bound enzymes in heart
and other tissues - Structural basis of regulation of
cardiac succinate dehydrogenase
R01HL16318-21 Biochemistry and pharmacology of Na-K
transport
ROlHL-16320-05 Vasoactive peptides which stimulate
smooth muscles (rats, human)
ROlHL-1651204 Lipoprotein metabolism and hormonal
regulation (chickens)
R01HL-ie628-05 Regulation of lipid metabolism (rats)
ROlHL-16633-04 Chemistry and biology of factor IX
activator (human, mice, rats)
ROlHL-16637-04 Development and regression of cardiac
hypertrophy (rats)
R01HL-ie647-05 Studies on the control of sickle cell crisis
(human)
R01HL-1668e-04 Properties of cytochrome oxidase (cattle,
bacteria)
POlHL-16833-04 0001 Hemoglobin and red cell system In
hemoglobinopathies - Motility, association and ligand
binding in hemoglobin-Hydrogen exchange
R01HL17194-03 Comparison of two inherited forms of
alpha-1-antitrypsln (human)
P60HL- 17269-04 0009 National heart and blood vessel
research and demonstration center - Physical methods
laboratory (high density lipoproteins)
' P60HL-17269-04 0011 National heart and blood vessel
research and demonstration center - Lipoprotem structure
laboratory (human)
PeOHL-17269-04 0013 National heart and blood vessel
research and demonstration center - Peptide synthesis
laboratory (human)
PeOHL-17269-04 0017 National heart and blood vessel
research and demonstration center - Cell membrane (dogs,
rabbits)
P01HL17382-05 0003 Chemical mediators of acute
pulmonary disorders - Chemical mediators relevant to
allergic reactions (human, guinea pigs)
P01HL17419-04 0001 Studies on mechanisms of
hemostasis • Structure and metabolism of fibrinogen
(human)
' POIHL- 178 12-04 0001 Thrombosis and plasma proteins ■
Thrombosis and plasma proteins (cattle, guinea pigs)
' R01HL17879-04 Molecular structure of the ouabain
sensitive ATPase (dogs)
' R01HL17896-03 Dehydropeptide renin substrates
ROlHL-18435-03 Properties of thrombin and Ac-globulin
(human, animals)
' POlHL-18576-03 0002 Thrombosis research program
project - Molecular basis of fibrin formation (human, cattle,
lamprey)
POlHL-18576-03 0011 Thrombosis research program
project - Proteolysis and platelet function (human, cattle,
rabbits)
POlHL-18576-03 0012 Thrombosis research program
project - Synthetic anticoagulant and thrombolytic agents
(dogs)
POlHL-18577-03 Lipoproteins-Cell surface interactions
' P01HL18577-03 0004 LIpoproteins-Cell surface
interactions - Analysis and chemical modification of
proteins in lipid transport (human, dogs)
POlHL-18577-03 0005 Lipoproteins-Cell surface
interactions - Chemical synthesis of apolipoproteins and
apoliprotein fragments
• POlHL-18577-03 0011 Lipoproteins-Cell surface
Interactions - Core laboratory 4
Structure-function relationships of human
Tracheal mucin synthesis in experimental
ROlHL-186 12-03 Thin filament control of heart contraction
(cattle)
ROlHL-18634-03 Quarternary structure of erythro and
chlorocruorins (Invertebrates)
R01HL187 14-04 Cardiovascular matrix -Morphogenesis
and maturation (human, chick embryo, mammal)
ROlHL-18746-02 Chemical studies on proteolipid
apoproteins (cattle)
P50HL18828-03 0003 Specialized center of research in
thrombosis - Structure and function of plasma coagulation
inhibitors (human)
P01HL18974-03 0011 Experimental neurogenic
hypertension program - Biochemistry and regulation of
brain tryptophane hydroxylase (rats)
** ROlHL-19084-03 Structure and function of serum
lipoproteins (human)
POlHL-19259-03 0001 DIgoxIn-specific antibody in human
therapy - Primary structure of monoclonal antibodies
(rabbits)
POIHL- 192 59-03 0002 Oigoxin-specific antibody in human
therapy - Chemical semi-synthesis of digoxin-specific
antibody (rabbits)
POlHL-197 17-02 0001 Response of the lung to injury -
Lung elastic tissue (animals)
ROlHL-20161-02 Role of gamma-carboxyglutamic add in
blood coagulation (human, cattle)
ROlHL-20500-02 Diabetic human brain microvascular
basement membrane (human)
ROlHL-20794-02 Prostaglandin synthesis in human
platelets (also in sheep, rabbit)
POlHL-20984-02 0004 Cellular mechanisms in cardiac
hypertrophy - Myofibril accumulation in cardiac and
vascular muscle cells in hypertrophy
P50HL-21006-02 0003 Specialized center of research in
arteriosclerosis - Transport of vitamin A in plasma (human,
rat)
R23HL-21208-02
factor VIII
R23HL-21369-02
bronchitis (rats)
** ROlHL-21471-02 Structure-function studies on actin and
myosin (human, protozoa, rabbits, cattle)
R01HL-21480-0I Structure, source and functions of
alveolar glycoproteins (human, rabbits)
ROlHL-21617-02 Biochemistry of lung proteoglycans
(rabbits, cattle)
ROlHL-21622-02 Structure and interactions of lung
proteoglycans (cattle)
ROlHL-21683-02 Purification of erythropoietin (human)
ROlHL-21686-02 Purification of erythropoietin (human)
ROlHL-21701-02 Purification of erythropoietin (human)
ROlHL-21831-05 Determining sequences from hemoglobin
messenger RNA (mice, chickens, rabbits)
R23HL-21894-01 Pulmonary angiotensin converting enzyme
(cattle)
ROlHL-21975-01 Studies on normal and abnormal factor
IX (human, dogs, cows)
ROlHL-221 15-02 Lipid-mobilization and diabetic
atherosclerosis (human)
ROlHL-221 19-01 Biochemistry of platelet function in
thrombosis and cell growth (rabbits)
" ROlHL-221 74-01 Assembly of membranes in heart and
yeast mitochondria
ROlHL-22208-02 Elastin structure, fibrogenesis and
disease (chickens, rabbits)
ROlHL-22288-01 Renin and precursors-Structure and
function (mice)
R23HL-22799-01 Interaction of the complement and
coagulation systems (monkeys)
ROlHL-22845-01 Response of cardiac myosin to
hypertrophic stress (rabbits)
ROlHL-22875-01 Crotalase-Chemistry, physiology, clinical
potential (rats, rabbits)
ROlHL-23200-01 Isolation of CA binding proteins from
erythrocytes (human)
R01HL-23233-0I Pulmonary artery intermediate filament
structure (cattle)
NOlHR-72922-01 Cystic fribrosis factor identication and
quantification (human)
NOlHR-72923-01 Cystic fibrosis factor identification and
quantification (human)
PROTEINS RECONSTITUTION
SEE ALSO ENZYME RECONSTITUTION
P50HL-14237-07 0004 Support for arteriosclerosis center
- Synthesis, secretion of normal, abnormal plasma
lipoproteins (rodents, monkeys)
P50HL-15062-07 0001 Study of lipoproteins, artery wall,
and atherosclerosis - Structure and molecular interactions
of serum lipoproteins (human, monkey)
ROlHL-16891-05 The folding of hemoglobin
P60HL-17269-04 0009 National heart and blood vessel
research and demonstration center - Physical methods
laboratory (high density lipoproteins)
P60HL-17269-04 0011 National heart and blood vessel
research and demonstration center - Lipoprotein structure
laboratory (human)
P60HL-17269-04 0013 National heart and blood vessel
research and demonstration center - Peptide synthesis
laboratory (human)
P60HL-17269-04 0017 National heart and blood vessel
research and demonstration center ■ Cell membrane (dogs,
rabbits)
ROlHL-20300-02 Histone H5 and avian erythropoiesis
(chickens, rabbits)
ROlHL-22135-01 Control of calcium fluxes across cardiac
membranes (dogs, rabbits, guinea pigs)
PROTEINS STRUCTURE
SEE PROTEINS-PEPTIDES STRUCTURE
PROTEINS TRANSPORT
SEE ALSO PROTEIN BINDING
ROlHL-00082-30 Transmembrane movements (barnacles,
frogs, rats)
** POlHL-09011-15 0015 A research and resource program
in blood - Regulation of synthesis and transport of diverse
proteins in liver (rats)
** POlHL-09011-15 0019 A research and resource program
in blood - The transport mechanism of mRNA (rat. yeast,
ascites cells)
P50HL-14197-07 0005 Support for center of research on
arteriosclerosis - Lipoprotein biosynthesis and degradation
in vivo and in vitro (human, animal)
P50HL-15062-07 0019 Study of lipoproteins, artery wall,
and atherosclerosis - Factors regulating lipoprotein-smooth
muscle cell interaction (monkey)
ROlHL-16512-04 Lipoprotein metabolism and hormonal
regulation (chickens)
ROIHL- 17898-03 Cell membranes and plasma lipoproteins
(human, swine)
** ROlHL-18692-03 Glycosaminoglycans and lipoproteins of
human plasma
** ROlHL-18736-03 Protein transport through arterial tissue
(rabbits)
P50HL-19153-02 0004 SCOR -Pulmonary edemas-Eitology,
pathogenesis - Physical mechanisms in lung transvascular
transport-Math models (sheep)
M P50HL-19155-02 Pathophysiology of pulmonary edema
** P50HL-19155-02 0002 Pathophysiology of pulmonary
edema - Non-invasive measurement of protein turnover in
human lung (also sheep)
** P50HL-19155-02 0004 Pathophysiology of pulmonary
edema - Physical and chemical effects of multiple
pulmonary emboli (sheep)
** P50HL 19155-02 0005 Pathophysiology of pulmonary
edema - Protein exchange sites and lymph protein
concentration in lung (mice, sheep)
" P50HL-19185-02 0004 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Fluid and protein transport
in fetal and newborn lung (sheep, rabbits)
ROlHL-19316-03 Study of glomerular permeability (fish,
turtle, frog, chordates, Crustacea)
** ROlHL-20061-02 Serum lipoproteins and cell cholesterol
metabolism (rats, human)
ROlHL-20391-03 Polydisperse LDL-Structure. metabolism
and function (human)
ROlHL-20460-03 Aortic histamine synthesis in diabetes
(rat)
ROlHL-21076-02 Lung fluid, protein exchange after
hemorrhagic shock (sheep)
** ROlHL-21176-02 Phospholipid exchange proteins in lung
tissue (lambs)
ROlHL-22053-02 The disordered lipid metabolism of
diabetes mellitus (chickens, mammals, human)
** ROlHL-22333-01 Cellular basis of small airways function
(rats)
ROlHL-22729-01 Intracellular degradation of newly
synthesized collagen (human, chick, rabbit)
** ROlHL-22924-01 The airway mucosal barrier (guinea pigs)
** R23HL-22933-01 Transvascular fluid and protein exchange
in the lung (sheep)
PROTEINURIA
SEE ALSO HEMOPROTEINS, MYOGLOBINURIA
ROlHL-02965-22 Metabolism of plasma lipoproteins (rats.
chickens, human)
ROlHL-16490-04
(rats, rabbits)
ROlHL-16603-05
(animals)
Structural basis of nephron filtration
Human and experimental renal diseases
PROTEOGLYCANS
SEE ALSO GLYCOPROTEINS
SEE ALSO HEMOPROTEINS. HAPTOGLOBINS
SEE ALSO METALLOPROTEINS. TRANSFERRIN
SEE ALSO POLYSACCHARIDES, GLYCOSAMINOGLYCANS.
SULFOMUCOPOLYSACCHARIDES
ROlHL-01803-23 0014 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Regenerated endothelium on lipid
accumulation in arterial wall (rabbit)
ROlHL-02942-22 Biochemistry of cardiovascular connective
tissue (human, cattle, primates)
P01HL-08805-15 0048 Regulation of ventilation and
pulmonary circulation - Permeability of alveolo-Capillary
membrane in normal pulmonary hypertensive lung
P01HL11310-12 0103 Mechanisms of cardiovascular
disease - Heparin-Metabolism and function
** POlHL-11310-12 0104 Mechanisms of cardiovascular
disease - Structure of connective tissue proteoglycans
(rabbits)
ROlHL-14262-07 Leukocyte proteases and their lung
targets (human, dogs, rabbits)
P50HL-15103-07 0014 A/S SCOR-Early natural history of
arteriosclerosis - Biochemistry of atherosclerotic lesions
(monkeys, human, cattle)
(contd)
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Onented signlflcanthf to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
PRO
** P01HI'1S832'06 0001 Chamtcilsttuctural ptadlspositions
to lung iniury Chemical composition ol lung connective
tissue proteins (human, animals)
ROIHL 16219 0b Mechanisms ol alheiogenesis in chronic
uremia (human, rats)
** ROIHL 17995 04 Cellular synthesis and release ol
mucopolysaccharides (rabbits)
■* ROIHL 1862503 Orjanuation ol arterial ground substance
(cattle)
ROIHI 1928/ 03 The antihypertensive function ol the
renal medulla (human, lats. rabbits)
•* POIHL 19717 02 0006 Response of the lung to iniury
Glycosaminoglycans and proteoglycans ol the lung (human,
rats, hamsters)
•• POIHL 19717 02 0010 Response of the lung to injury •
Proteoglycans in lung function and structure (hamsters)
ROIHL 20635 03 Factors in lung development (rat and
chick embryo)
ROIHL 2109502 Enzymes of M tuberculosis and
obstructive lung disease (human, rodents)
** ROIHL 21612 02 Biochemistry of lung proteoglycans
(human, rabbits)
ROIHL 2161501 Structural studies of lung heparinoid
polysaccharides (cattle)
** R01HL2161702 Biochemistry of lung proteoglycans
(rabbits, cattle)
" ROlHL-21622 02 Structure and interactions of lung
proteoglycans (cattle)
** ROlHL-2162601 Proteoglycans of animal lung
parenchyma (cattle, pigs, rabbits)
** ROlHL-21641 02 Structural studies of lung proteoglycans
(pigs, cattle, rabbits)
** ROlHL-21646-02 Biosynthesis of fractionated
proteoglycans of lung (rabbits)
** ROlHL-2164901 Biochcmistrv of lung proteoglycans
(mammals)
ROlHL-2211901 Biochemistry of platelet function in
thrombosis and cell grovith (rabbits)
PROTEOGLYCANS, MUCIN
ROlHL-1427107 Physico-chemical properties of tracheal
mucus (dogs, frogs)
** ROlHL-14844-06 Mucous glycoprotein in human respiratory
epithelium (also wheat)
** ROIHL 20868-02 Regulation of glycoprotein biosynthesis in
lung (swine)
** R23HL-2136902 Tracheal mucin synthesis in experimental
bronchitis (rats)
PROTEOUPIDS
SEE ALSO LIPOPROTEINS
** R01HL18746-02 Chemical studies on proteolipid
apoproteins (cattle)
PROTEOLYSIS
ROlHL-01662-25 Equilibria in the fibrinogen-fibrin
conversion (human, cattle)
ROlHL-1282009 In vitro regulation of prothrombin
activation
ROlHL-13160-08 Human thrombin (also cattle)
POlHL-1326207 0015 Arterial wall m atherosclerosis -
Crosslinkage biosynthesis in aortic elastln and collagen
(animals)
P50HL14217-08 0062 Specialized center of research in
thrombosis - Coagulation section -Factor VIII and Factor XII
(human, cattle)
R01HL1561506 Structure-function studies of human
factor VIII/vWF
ROlHL-15616-04 Platelet membrane proteins in
aggregation (human)
R01HL15793-06 Molecular aspects of erythrocyte
membrane resealing (human)
M POlHL-15832-06 Chemical-structural predispositions to
lung injury
** POlHL-15832-06 0004 Chemical-structural predispositions
to lung injury - Proteolytic activity leucocytes in patients
with obstructive lung disease
ROlHL-15965-06 Experimental atherosclerosis and elastin
metabolism (chicks)
ROIHL-16725-03 Physiological regulation of pulmonary
surfactant (dogs, rats)
** P50HL-1 7665-04 0029 Study of ischemic heart disease ■
Myocardial protein synthesis and degradation in low oxygen
states (rabbit, dog)
** ROlHL-18258-04 Regulation of protein degradation in
heart (rats)
ROIHL-18435-03 Properties of thrombin and Ac-globulin
(human, animals)
** P01HL-18576-03 0011 Thrombosis research program
project - Proteolysis and platelet function (human, cattle.
rabbits)
ROlHL-1883404 Metal-dependent complex formation in
blood coagulation (human, cattle)
P50HL-19I9002 0004 Pulmonary SCOR-Pathophysiology.
management of IRDS - Type II cells-Control of protein
turnover (rabbit)
ROlHL-1964803 Myocardial protein degradation (dogs.
rabbits)
** POlHL-19717-02 0003 Response of the lung to injury -
The role of elastolysis in emphysema (hamsters, rabbits)
" POlHL-19717-02 0005 Response of the lung to injury •
Studies on proteolysis and lung disease (human, animals)
ROlHL-20344 02
tissue (tats)
ROIHL 2066602
(human)
ROIHL 21543 02
44 1
Regulation of protein turnover in lunii
Cell biology of platelet preservation
Structure function relation ol blood
clotting proteins (rabbits)
ROIHI 21544 02 Proteins of coagulation and Hageman
factor pathways (human, goats)
R23HL 21730 01 vWagll A new vWD deficient antigen
(human)
** ROIHL 22729 01 Intracellular degradation of newly
synthesized collagen (human, chick, rabbit)
ROIHL 22955 01 inetics ol prothrombin activation
** ROIHL 22980 01 Kinetic and mechanistic studies of blood
coagulation (human, cattle)
ROIHL 2299601 Venom proteases Action on plasma
protease inhibitors (human)
R01HL24021 02 Erythocyte membrane sulfhydrls and Rh
activity (human)
PROTEOLYTIC AGENTS (NONENZYMATIC)
POIHL 1559605 0003 Coagulation, fibrinolysis,
hemostasis and hepatitis Plasmin degraded fibrinogen
fractions (human)
PROTEOLYTIC ENZYMES
SEE PROTEASES AND PEPTIDASES
PROTEUS
SEE BACTERIA. ENTEROBACTERIACEAE, PROTEUS*
PROTHROMBIN
SEE BLOOD COAGULATION. PROTHROMBIN
PROTHROMBIN TIME
SEE BLOOD COAGULATION TESTS. PROTHROMBIN TIME*
PROTON ACCELERATORS
SEE RADIATION. PARTICLE ACCELERATORS
PROTON TRANSPORT
SEE CHEMICAL TRANSFER. HYDROGEN TRANSPORT
PROTOPORPHYRIA
SEE METABOLIC DISORDERS INBORN. PORPHYRIA,
PROTOPORPHYRIA
PROTOZOA, MASTIGOPHORA, TRYPANOSOMA
CRUZI
ROlHL-2089503 0006 Cineangiographic studies of
cardiovascular system - Cardiomyopathy-Hemodynamic,
radiologic, morphologic abnormalities (dog. rabbit)
PROWER FACTOR
SEE BLOOD COAGULATION. FACTOR X
PSEUDOCHOLINESTERASE
SEE CHOLINE ESTERASES
PSEUDOCHOLESTANE-3BETA-OL
SEE CHOLESTANE SERIES 5-BETA. COPROSTEROL
PSEUDOHEMOPHILIA, VASCULAR
SEE BLOOD COAGULATION DISORDERS, VON WILLEBRAND'S
DISEASE
PSEUDOMONAS
SEE BACTERIA. PSEUDOMONADALES, PSEUDOMONAS*
PSEUDOMONAS AERUGINOSA
SEE BACTERIA. PSEUDOMONADALES. PSEUDOMONAS
AERUGINOSA*
PSEUDOPLAGUE VIRUS AVIAN
SEE VIRUSES. PARAMYXOVIRUSES. NEWCASTLE DISEASE
VIRUS
PSITTACOSIS AGENT
SEE CHLAMYDIA. PSIHACOSIS AGENT
PSITTACOSIS-LYMPHOGRANULOMA-TRACHOMA
GROUP AGENT
SEE CHLAMYDIA
PSYCHIATRIC AIDS
SEE MENTAL HEALTH PERSONNEL ADJUNCT
PSYCHIC ACTIVITY LEVEL
SEE ALSO NEUROLOGIC MANIFESTATIONS. UNCONSCIOUSNESS
SEE ALSO PSYCHOLOGY. COGNITION. CONSCIOUSNESS
SEE ALSO PSYCHOLOGY. MOTIVATION
SEE ALSO PSYCHOLOGY. PERFORMANCE
** P01HL10539-12 0023 Pathophysiology of circulation -
The relaxation response and therapy of disease states
(human)
POlHL-1053912 0031 Pathophysiology of circulation •
Post myocardial infarction care-Psychological aspects
(human)
** POlHL-1053912 0065 Pathophysiology of circulation -
Physiologic correlates of relaxation (human)
** POlHL-10539-12 0066 Pathophysiology of circulation -
Usefulness of relaxation response in industrial settings
R01HL19568-03 Hypertension-Analysis of drug and
behavioral therapies (human)
psr
PSYCHIC ACTIVITY LEVEL, AROUSAL
POIHI 08682 I'l 0006 Regulation of lh« lardiovatcultr
system Cardiovascular studies ot mammalian hiberndort
(sciuromorpha)
POIHL 08682 15 0031 Regulation ot the cardiovascular
system Cardiac electrophysiology in hibernation (ground
squirrel, marmot)
ROIHL 14713 06 Hypothermia and the hear! (bal-., guinea
PiUs)
ROIHL 20800 17 Neural basis of respiratory and
vasomotor activity (tats)
** ROIHL 21318 02 Mechanisms of emotions' asthma
triggering effect (human)
ROIHL 22809 01 Coronary prone behavior and
cardiovascular reactivity (human)
PSYCHIC ACTIVITY LEVEL, ATTENTION
POIHL 08899 14 0066 Tolerance to respiratory gases in
health and disease Neurophysiological effects of inert
gases in man
POlHL-08899 14 0067 Tolerance to respiratory gases in
health and disease Inert gas influences upon visual
function in man
PSYCHIC ACTIVITY LEVEL, RELAXATION
ROIHL 1881403 Behavioral tactics for clinical cardiac
control (human)
ROIHL 22547 01 Behavioral treatment of Raynaud's
disease (human)
PSYCHIC ACTIVITY LEVEL, SLEEP
SEE ALSO HEALTH. PHYSICAL ACTIVITY. REST
SEE ALSO NEUROLOGIC MANIFESTATIONS. SLEEP DISORDERS
SEE ALSO SENSORY DEPRESSION. ELECTRONARCOSIS
ROlHL-02888 22 Interrelationships of circulation and
respiration (opossum, cats)
** POlHL-06835-17 0044 Cardiovascular disease
Baroreceptors in control of blood pressure during sleep
(dogs)
ROlHL-07776-15 Sudden death and cardiac arrhythmias
(human, dogs, cats)
ROlHL-08789-11 Respiratory muscles and ventilatory
control in man (and dogs)
POlHL-08899-14 0033 Tolerance to respiratory gases in
health and disease - Acid-base related Influences of
hypoxia (human)
P01HL08899-14 0041
health and disease -
Tolerance to respiratory gases in
Blood gas transport and brain
circulatory control (human)
P01HLI3108-09 0019 Clinical heart transplantation ■
Effect of autonomic nervous system on arrhythmias
(human)
ROlHL-1410207 Human physiology at 5360 meters-
Mountain environment
POlHL-14388-07 0179 Regulation of the circulation in
pathological states - Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
POlHL-14985-07 0013 Adaptation to hypoxia ■ Chronic
mountain sickness (men)
ROlHL-16022-05 Determinants of the ventilatory response
to hypoxia (goats, cats)
ROlHL-17907-04 Brain regulation of cardiac arrhythmia
(pigs. cats, rats)
** ROlHL-18007-05 Neural mechanisms controling motor act
of breathing (cats, human)
ROlHL-18798-04 0003 Nervous and ionic factors in
sudden cardiac death - Lett stellectomy in the prevention
of sudden death (dogs)
P50HL-19187-02 0011 Pediatric pulmonary SCOR -Hyaline
membrane disease - Effects of hypoxia and hypercapnia on
developing nervous system (monkey, human)
ROlHL-19864-03 0003 Blood pressure of children and
young adults - Heart rate and blood pressure-Consistency
in infancy (human)
R23HL-20968-02 Respiratory failure-Control and muscle
dysfunction (human)
** ROlHL-21257-02 Breathing in sleep-Airway control and
blood gases (cats)
ROlHL-22418-01 Neural control of cardiorespiratory
function (cats)
PSYCHIC ACTIVITY LEVEL, TROPHOTROPIC STATE
SEE ALSO PSYCHOLOGY. CONDITIONING, AUTOGENIC AND
INTERNAL CONTROL
ROlHL-21323-02 Raynaud's disease and temperature self-
regulation (human)
PSYCHIC ACTIVITY LEVEL, TROPHOTROPIC
STATE, MEDITATION
POlHL-10539-12 0023 Pathophysiology of circulation -
The relaxation response and therapy of disease states
(human)
POlHL-10539-12 0064 Pathophysiology of circulation -
Exercise physiology and pathophysiology (human)
POlHL-10539-12 0065 Pathophysiology of circulation -
Physiologic correlates of relaxation (human)
POlHL-10539-12 0066 Pathophysiology of circulation •
Usefulness of relaxation response in industrial settings
** P50HL-18323-04 0047 SCOR hypertension center -
Transcendental meditation and self-hypnosis-Hypertension
treatment (human)
ROlHL-1984402 Behavioral control ot essential
hypertension (human)
(contd)
•Excludes routine mettiodology OR covers only general projects which preclude indexing at ttie specific level.
•'Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix tor investigator's name and grant number.
PSY
442
PSY
Cardiovascular adjustment to behavioral
Impact of emotion on coronary arteries
ROlHL-22547-01 Behavioral treatment of Raynaud's
disease (human)
PSYCHIC ENERGIZERS
SEE PSYCHOPHARMACOLOGICAL AGENTS, ANTIDEPRESSANTS
PSYCHOBIOLOGY, PSYCHOPHYSIOLOGY
SEE ALSO BRAIN INTERHEMISPHERIC ACTIVITY, CEREBRAL
DOMINANCE
SEE ALSO ENVIRONMENT. ORIENTATION
SEE ALSO INFORMATION PROCESSING AND CONTROL
(NEURAL)
SEE ALSO NEUROPHYSIOLOGY, REFLEX
SEE ALSO NEUROPSYCHOLOGY (GENERAL)*
SEE ALSO NUTRIENT INTAKE ACTIVITY (GENERAU
SEE ALSO PSYCHIC ACTIVITY LEVEL
SEE ALSO PSYCHOLOGIC STRESS
SEE ALSO PSYCHOMOTOR FUNCTION
SEE ALSO PSYCHOPHYSIOLOGIC DISORDERS
SEE ALSO SENSORY-PERCEPTUAL PROCESSES, SENSORY
MECHANISMS (GENERAL)
** ROlHL-0342918 Central nervous system and coronary
heart disease (human)
** ROlHL-17958-04 Circulatory effects of operant
cardiovascular control (baboons)
ROlHL-19257-03
stress (dog)
*• ROlHL-19567-03
(human)
ROlHL'19568-03 Hypertension-Analysis of drug and
behavioral therapies (human)
R01HL-19e80-01 Cardiac correlates of behavioral stress In
animals (dog)
ROlHL-1983909 Factors in youth predisposing to chronic
diseases (former college students)
*• R01HL19844-02 Behavioral control of essential
hypertension (human)
R01HL19929-03 High blood pressure in the young,
prevalence and precursors (human)
" ROlHL-20034-03 Hypertension-Psychophysiologic and
genetic precursors (human)
** ROlHL-2036401 Episodic hypertension associated with
human behavior (air traffic controllers)
** ROlHL-20384-09 Social stimulation, RNA and
cardiovascular disease (animals)
ROlHL-2063702 Recovery after heart surgery-Bio-
behavioral factors (human)
** ROlHL-2086101 Cardio-respiratoryrenal stress reactions
(dogs)
ROlHL-21010-02
40,000 persons
** ROlHL-21319-02
behavior (human)
** ROlHL-2142602 Learned heart rate control (human)
•* R01HL-21532-02 Cardiovascular homeostasis and learning
(frogs, rats, human)
PSYCHGGENETICS-BEHAVIORAL GENETICS
P50HL19362-02 0003 A/S SCOR -Atherosclerosis in
nonhuman primates - Herltability of characters related to
atherosclerosis (baboons)
PSYCHOLOGIC STRESS
SEE ALSO PSYCHOPHYSIOLOGIC DISORDERS
R01HL-07776-15 Sudden death and cardiac arrhythmias
(human, dogs, cats)
P01HL10539-12 0031 Pathophysiology of circulation -
Post myocardial infarction care-Psychological aspects
(human)
POlHL-13108-09 0019 Clinical heart transplantation -
Effect of autonomic nervous system on arrhythmias
(human)
** ROlHL-13454-08 Behavioral stress and cardiomyopathy
(monkeys, cats)
R01HL16760-05
(dogs)
** ROlHL-17580-04
disease (men)
ROlHL-1770604 Psychosocial hypertension,
catecholamines and drugs (mice)
** ROIHL- 17907-04 Brain regulation of cardiac arrhythmia
(pigs, cats, rats)
ROlHL-1 7958-04 Circulatory effects of operant
cardiovascular control (baboons)
** P50HL-18318-03 0012 Pathogenesis and complications of
hypertension - Behavioral factors in hypertension (human)
R25HL-1841803 Role of a supporting partner in
adherence (human)
R01HL18467-03 Fingertip blood flow in normals and
Raynaud's disease (human)
ROlHL-18776-04 Prevention of acute and fatal
cardiovascular disease (human)
R01HL18783-04 Detection and control of ventricular
premature beats (human)
** ROlHL-18907-03 Objective evaluation early after Ml and
heart surgery (human)
** R01HL18976-03 Blood pressure control-Relation to
behavioral stress (human, dog)
" ROlHL-19204-03 Environmental factors in hypertension
(Rhesus monkeys)
** ROlHL-19257-03 Cardiovascular adjustment to behavioral
stress (dog)
** ROIHL- 19680-01 Cardiac correlates of behavioral stress in
animals (dog)
Glycemia, other traits and CV death In
Interpersonal stress and coronary-prone
Dynamic control of coronary blood flow
The impact of stress on coronary heart
ROlHL-19869-03 Antecedents of adolescent hypertension
(human)
ROlHL-19974-02 Psychologic-behavioral influences on
heart pathology (rats)
R01HL-20034-a3 Hypertension-Psychophysiologic and
genetic precursors (human)
ROlHL-20124-02 Coronary risk factors (human)
ROlHL-20159-03 Genetic epidemiology of precursors of
hypertension (human)
ROlHL-2038409 Social stimulation, RNA and
cardiovascular disease (animals)
ROlHL-20655-02
children
ROlHL-2086101
Autonomic predictors of hypertension in
Cardio-respiratoryrenal stress reactions
Interpersonal stress and coronary-prone
Behavioral changes in post Infarction
Stanford five city multifactor risk
(dogs)
*• ROlHL-21319-02
behavior (human)
R01HL-21427-02
patients
R18HL-21906-01
reduction study
ROlHL-22065-01 Intractability, medication, and coping
styles in asthma (human)
ROlHL-22378-01 Psyco-somatic predictors of CHD in
adolescence (human)
ROlHL-22472-01 Smoking risk-factor reduction-
Maintenance strategies (human)
** ROlHL-225 14-01 Behavior patterns, stress, and
catecholamines
ROlHL-22740-01 Behavior and cardiovascular disease-
Basic mechanisms (human)
ROlHL-22809-01 Coronary-prone behavior and
cardiovascular reactivity (human)
** ROlHL-23078-01 Psychosocial stress and sudden coronary
death (human)
PSYCHOLOGICAL ADAPTATION
ROlHL-19974-02 Psychologic-behavioral Influences on
heart pathology (rats)
R01HL-20e55-02 Autonomic predictors of hypertension in
children
PSYCHOLOGICAL ADAPTATION, COPING
BEHAVIOR
SEE ALSO PSYCHOLOGY, DEFENSE MECHANISMS
POlHL-10539-12 0031 Pathophysiology of circulation -
Post myocardial Infarction care-Psychological aspects
(human)
P60HL-17269-04 0042 National heart and blood vessel
research and demonstration center - Social-psychological
smoking deterrents in schools
P50HL- 183 18-03 0012 Pathogenesis and complications of
hypertension - Behavioral factors In hypertension (human)
R25HL-18418-03 Role of a supporting partner in
adherence (human)
ROlHL-18976-03 Blood pressure control-Relation to
behavioral stress (human, dog)
ROlHL-2131902 Interpersonal stress and coronary-prone
behavior (human)
** ROlHL-22065-01 Intractability, medication, and coping
styles in asthma (human)
** ROlHL-2251401 Behavior patterns, stress, and
catecholamines
PSYCHOLOGICAL ADAPTATION, EMOTIONAL
ADJUSTMENT
SEE ALSO PSYCHOLOGY SOCIAL, SOCIAL ADJUSTMENT
R01HL15790-06 Follow-up study of acute coronary heart
attacks (human)
PSYCHOLOGICAL IMPACT OF DISEASES OR
MEDICAL PROCEDURES
SEE BEHAVIORAL MEDICINE
PSYCHOLOGICAL TESTS (GENERAL)*
SEE ALSO NEUROPSYCHOLOGICAL TESTS-
SEE ALSO PSYCHOMETRICS
POlHL-08899-14 0046 Tolerance to respiratory gases in
health and disease - Studies in senile elderly individuals
ROlHL-19929-03 High blood pressure In the young,
prevalence and precursors (human)
PSYCHOLOGICAL TESTS, BEHAVIOR
ASSESSMENT-MEASUREMENT*
SEE ALSO PSYCHOLOGY, BEHAVIOR PREDICTION
ROlHL-03429-18 Central nervous system and coronary
heart disease (human)
** ROlHL-22021-01 Asthma in families- Behavior analysis of
family interaction pattern
PSYCHOLOGICAL TESTS, PERSONALITY
ASSESSMENT-MEASUREMENT*
SEE ALSO PSYCHOLOGICAL TESTS (GENERAL)*
ROlHL-21319-02 Interpersonal stress and coronary-prone
behavior (human)
ROlHL-21427-02 Behavioral changes in post infarction
patients
PSYCHOLOGY, ATTITUDE TO HEALTH AND
HEALTH PROBLEMS
POlHL-10539-12 0031 Pathophysiology of circulation ■
Post myocardial infarction care-Psychological aspects
(human)
** P50HL14236-05 0013 Prevention of premature
arteriosclerosis - Patient compliance
P60HL-15157-07 0003 Comprehensive center for sickle
cell disease - Public education
P60HL-15158-07 0009 Comprehensive sickle cell center -
Counseling and social services
P60HL-15160-07 0003 Center for sickle cell disease -
Genetic counseling in hemoglobinopathies-Oimensions,
effectiveness
P60HL-15ie2-07 0010 Comprehensive sickle cell center -
Core program-Community outreach and education program
P60HL-15162-07 0011 Comprehensive sickle cell center -
Core program -Genetic counseling and diagnostic screening
PeOHL-15168-07 0003 Comprehensive sickle cell disease
center - Sickle cell education and training program
ROlHL-15790-06 Follow-up study of acute coronary heart
attacks (human)
P60HL- 15996-06 0004 Cincinnati comprehensive sickle
cell center - School adjustment of sickle cell patients
P60HL-15999-0S 0004 Miami comprehensive sickle cell
center - Education, screening and counseling
** R25HL-17056-01 Improving patient compliance through
nursing action
P60HL- 17269-04 0036 National heart and blood vessel
research and demonstration center - Public education
P60HL-1729204 0024 Vermont Lung Center - Education
and media resources unit
** R25HL-1841403 Hypertension-Family strategies for
patient adherence
R25HL-18418-03 Role of a supporting partner In
adherence (human)
R25HL 18424-03 Blood pressure education in an industrial
setting (human)
ROIHL 20637-02 Recovery after heart surgery-Blo-
behavioral factors (human)
ROlHL'20910-02 The alternative diet for coronary disease
prevention (human)
** ROlHL-2206501 Intractability, medication, and coping
styles in asthma (human)
R23HL22345-02 0001 Behavioral cardiovascular
compliance strategies Long term modification of dietary
patterns (human)
** R23HL-22345-02 0002 Behavioral cardiovascular
compliance strategies - Compliance with antihypertensive
medication regimens (human)
ROlHL-22380-01 Detroit hypertension control program
** ROlHL-22472-01 Smoking risk-factor reduction-
Maintenance strategies (human)
ROlHL-22847-01 Test for adherence to diets rich In
linoleic acid
R23HL-22947-01 Experimental systems to improve youth
behavior (smoking prevention)
ROlHL-23078-01 Psychosocial stress and sudden coronary
death (human)
P60HL-23282-01 9001 Comprehensive hospital/community
sickle cell center - Core-lnstitutlonalization of education.
screening and counseling
NOlHR-72973-01 Health education and attitudes of family
toward asthmatic children
PSYCHOLOGY, ATTITUDES (AND RELATED)
P50HL-1831803 0012 Pathogenesis and complications of
hypertension - Behavioral factors in hypertension (human)
PSYCHOLOGY, BEHAVIOR
SEE ALSO BEHAVIORAL SCIENCES (DEVELOPMENTAL) STUDY
SECTION
SEE ALSO CHILD MENTAL DEVELOPMENT, CHILD BEHAVIOR
SEE ALSO FAMILY, MATERNAL BEHAVIOR
SEE ALSO NUTRIENT INTAKE ACTIVITY, DRINKING BEHAVIOR
(WATER)
SEE ALSO NUTRIENT INTAKE ACTIVITY, FEEDING (EATING)
BEHAVIOR
SEE ALSO PSYCHOLOGICAL ADAPTATION, COPING BEHAVIOR
SEE ALSO PSYCHOLOGY, EMOTIONS
SEE ALSO PSYCHOLOGY, PERFORMANCE
SEE ALSO PSYCHOLOGY, PERSONALITY
SEE ALSO PSYCHOLOGY SOCIAL. INTERPERSONAL RELATIONS
SEE ALSO PSYCHOLOGY SOCIAL. SOCIAL BEHAVIOR
ROlHL-18589-03 Psychosocial factors and outcome in
coronary disease (human)
PSYCHOLOGY, BEHAVIOR, AGGRESSION
SEE ALSO PSYCHOLOGY, BEHAVIOR. ESCAPE REACTION
ROlHL-19974-02 Psychologic-behavioral influences on
heart pathology (rats)
PSYCHOLOGY, BEHAVIOR, ESCAPE REACTION
ROlHL-19974-02 Psychologic-behavioral influences on
heart pathology (rats)
PSYCHOLOGY, BEHAVIOR, GOAL-STRIVING
** ROlHL-22472-01 Smoking risk-factor reduction-
Maintenance strategies (human)
PSYCHOLOGY, BEHAVIOR ANIMAL
SEE ALSO PSYCHOLOGY, BEHAVIOR, ESCAPE REACTION
R01HL-17706-04 Psychosocial hypertension,
catecholamines and drugs (mice)
ROlHL-17958-04 Circulatory effects of operant
cardiovascular control (baboons)
P50HL-1936202 0003 A/S SCOR-Atherosclerosis In
nonhuman primates - Heritability of characters related to
atherosclerosis (baboons)
(coiitd)
'Excludes routine methodokjgy OR nwers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
rsv
P50HL1936202 0005 A/S SCOR- Ath«io5cl«fosis tn
nonhuman pdmales Hybiidiiation to ptoduct piimate
model ot atherosclerosis (baboon. Rhesus)
•* P50HI 19362 02 000? A/S SCOR Atherosclerosis m
nonhuman primates Behavior type, cigarette smokint and
atherosclerosis (baboon)
•* PSOHL 19362 02 0014 A/S SCOR Atherosclerosis in
nonhuman primates Cote laboratory Behavior observation
and manipulation (baboon)
R23HL22747 01 Cardiodynamlcs and hypertension under
cerebellar control (dogs)
PSYCHOLOGY, BEHAVIOR PREDICTION
SEE ALSO PSYCHOLOGICAL TESTS, BEHAVIOR ASSESSMENT
MEASUREMENT*
*• R25HL 1840603 Adherence to hypertensive medical
regimens (human)
** R25HL 18414-03 Hypertension-Family strategies for
patient adherence
** R25HL 18418-03 Role of a supporting partner in
adherence (human)
** R25HL 18424 03 Blood pressure education in an industrial
setting (human)
PSYCHOLOGY, BRAIN CONTROL
SEE ALSO BRAIN STIMULATORS ELECTRONIC
SEE ALSO PSYCHOLOGY. CONDITIONING. AUTOGENIC AND
INTERNAL CONTROL
SEE ALSO PSYCHOTHERAPY. BEHAVIOR MODIFICATION
P01HL-0629S-18 0007 Cardiovascular and pulmonary
adaptation to stress Cardiovascular control during
isometric exercise (cats)
PSYCHOLOGY, COGNITION
SEE ALSO PSYCHOLOGY. LEARNING
SEE ALSO PSYCHOLOGY. PERFORMANCE
SEE ALSO SENSORY-PERCEPTUAL PROCESSES. PERCEPTION
POlHL-08899-14 Tolerance to respiratory gases in health
and disease
Tolerance to respiratory gases in
Oxygen effects upon CNS and sensory
M
POlHL-08899-14 0043
health and disease -
functions (human)
POlHL-08899-14 0044
health and disease
Tolerance to respiratory gases in
Influence of high oxygen pressures on
cognition and performance
Tolerance to respiratory gases in
Studies In normal subjects
Tolerance to respiratory gases in
Studies in senile elderly individuals
Tolerance to respiratory gases in
Studies of intermittent exposure in
POlHL-08899-14 0045
health and disease
POlHL-08899-14 0046
health and disease
POlHL-08899-14 0057
health and disease
man
POlHL-08899-14 0065 Tolerance to respiratory gases in
health and disease - Adaptation and effects of narcotic
gases exposure (human)
** POlHL-08899-14 0066 Tolerance to respiratory gases in
health and disease - Neurophyslologlcal effects of inert
gases In man
POlHL-08899-14 0067 Tolerance to respiratory gases in
health and disease - Inert gas Influences upon visual
function in man
ROlHL-20724-01 Behavioral consequences of hypertension
(human)
** ROlHL-22472-01 Smoking risk-factor reduction -
Maintenance strategies (human)
ROlHL-22740-01 Behavior and cardiovascular disease -
Basic mechanisms (human)
PSYCHOLOGY, COGNITION, CONSCIOUSNESS
ROlHL-19248-03 Breathing pattern variation and
mechanical Influences
PSYCHOLOGY, COGNITION, DECISION /MAKING
P60HL-17292-04 0008 Vermont Lung Center - Respiratory
physiology-Teaching, learning and auditing problem-solving
skills
PSYCHOLOGY, COGNITION, EXPECTANCY
R25HL-18414-03 Hypertension -Family strategies for
patient adherence
ROlHL-19680-01 Cardiac correlates of behavioral stress In
animals (dog)
PSYCHOLOGY, COGNITION, PROBLEM SOLVING
** P60HL-1 7292-04 0008 Vermont Lung Center - Respiratory
physiology-Teaching, learning and auditing problem-solving
skills
PSYCHOLOGY, CONDITIONING
SEE ALSO PSYCHOLOGY, LEARNING
SEE ALSO PSYCHOLOGY. LEARNING, HABITUATION
ROlHL-16656-06 Lett ventricular function in exercise
(dogs)
ROlHL-17907-04 Brain regulation of cardiac arrhythmia
(pigs, cats, rats)
** ROIHL- 19680-01 Cardiac correlates of behavioral stress in
animals (dog)
" ROlHL-20861-01 Cardlo-resplratoiy-renal stress reactions
(dogs)
PSYCHOLOGY, CONDITIONING, AUTOGENIC
AND INTERNAL CONTROL
SEE ALSO PSYCHOLOGY. BRAIN CONTROL
443
POIHL 10539 12 0023 Pathophyjiology at circulation
The relaxation lesponse and therapy of disease stales
(human)
POIHI 10539 1? 0066 Pathophysiology of circulation
Usefulness ol relaxation lesponse in indusliial settings
POIHL 143880/ 0150 Regulation ot the circulation in
pathological states Mechanism ol the antihypertensive
effect ol training (lats)
ROIHL 16292 05 0009 Surgery and non-obstructive
coronary insudiciency Exercise and supply demand
balance (human)
*• POIHL 16910 05 0007 Regulation ol the peripheral
circulation CNS -Behavioral influences on circulation
(baboons)
ROIHL 17958 04 Circulatory effects of operant
cardiovascular control (baboons)
*' P50HL 18323-04 0047 SCOR hypertension center -
Transcendental meditation and sell hypnosis Hypertension
treatment (human)
** ROIHL 18814-03 Behavioral tactics lor cirnical cardiac
control (human)
** ROIHL 18823 02 Physiological correlates of conditioned
blood pressure (human)
POIHL 1897403 0006 Experimental neurogenic
hypertension program Model of sustained arterial
hypertension (cats)
** ROlHL-19343 03 Behavioral influences on cardiac
contractility (monkeys)
P50HL- 19362-02 0011 A/S SCOR Atherosclerosis in
nonhuman primates ■ Chronic hypertension Induced by
operant conditioning techniques (baboon)
** ROlHL-19568-03 Hypertension Analysis of drug and
behavioral therapies (human)
** ROlHL-19844-02 Behavioral control ot essential
hypertension (human)
ROlHL-213 18-02 Mechanisms of emotions' asthma
triggering effect (human)
** ROlHL-21323 02 Raynaud's disease and temperature self-
regulation (human)
** ROlHL-21426-02 Learned heart rate control (human)
** ROlHL-21532-02 Cardiovascular homeostasis and learning
(frogs, rats, human)
ROlHL-22506-01 Hemodynamics of the clinical
hypertensions
** ROlHL-22547-01 Behavioral treatment of Raynaud's
disease (human)
PSYCHOLOGY, CONDITIONING, AVOIDANCE
ROlHL-19680-01 Cardiac correlates of behavioral stress in
animals (dog)
ROlHL-19974-02 Psychologic-behavioral influences on
heart pathology (rats)
ROlHL-20861-01 Cardio-respiratory-renal stress reactions
(dogs)
R01HL21532-02 Cardiovascular homeostasis and learning
(frogs, rats, human)
PSYCHOLOGY, CONDITIONING, EXTINCTION
ROlHL-18823-02 Physiological correlates of conditioned
blood pressure (human)
PSYCHOLOGY, CONDITIONING, OPERANT
ROlHL-091 54-14 Central control of distribution of organ
blood flow (monkeys)
** ROlHL-17958-04 Circulatory effects of operant
cardiovascular control (baboons)
R25HL-18424-03 Blood pressure education in an industrial
setting (human)
ROlHL-18823-02 Physiological correlates of conditioned
blood pressure (human)
P50HL-19362-02 0006 A/S SCOR-AtherosclerosIs in
nonhuman primates - Effects of cigarette smoking on
atherosclerosis (baboon)
P50HL-19362-02 0008 A/S SCOR -Atherosclerosis in
nonhuman primates - Lung structure and function in
cigarette smoking (baboon)
P50HL-19362-02 0011 A/S SCOR -Atherosclerosis in
nonhuman primates - Chronic hypertension induced by
operant conditioning techniques (baboon)
P50HL-19362-02 0014 A/S SCOR-Atherosclcrosis in
nonhuman primates - Core laboratory -Behavior observation
and manipulation (baboon)
ROlHL-19680-01
animals (dog)
ROlHL-20861-01
(dogs)
ROlHL-21532-02
Cardiac correlates of behavioral stress in
Cardio-resplratory-renal stress reactions
Cardiovascular homeostasis and learning
(frogs, rats, human)
PSYCHOLOGY, CONDITIONING,
REINFORCEMENT
SEE ALSO PSYCHOLOGY, LEARNING. REINFORCEMENT
POlHL-16910-05 0007 Regulation of the peripheral
circulation - CNS-Behavloral Influences on circulation
(baboons)
ROlHL-17958-04 Circulatory effects of operant
cardiovascular control (baboons)
ROlHL-21532-02 Cardiovascular homeostasis and learning
(frogs, rats, human)
PSYCHOLOGY, DEFENSE MECHANISMS
SEE ALSO PSYCHOLOGICAL ADAPTATION, COPING BEHAVIOR
ROlHL-206 55-02 Autonomic predictors of hypertension In
children
ROIHL 22/40 01 Behavior and cardiovitcular dittiM
Basic mechani%ms (human)
PSYCHOLOGY, DEFENSE MECHANISMS, DENIAL
ROIHl 1956/03 Impact ol emotion on coronary aileiiei
(human)
ROIHI 22065 01 Intractability, medication, and coping
styles in asthma (human)
PSYCHOLOGY, EMOTIONAL DEPENDENCY-
INDEPENDENCY
ROIHL 22065 01 Intractability, medication, and coping
styles in asthma (human)
ROIHL 22472 01 Smoking risk laclor reduction
Maintenance strategies (human)
PSYCHOLOGY, EMOTIONS
SEE ALSO PSYCHOLOGIC STRESS
SEE ALSO PSYCHOLOGICAL ADAPTATION. EMOTIONAL
ADJUSTMENT
SEE ALSO PSYCHOLOGY ABNORMAL. EMOTIONAL DISORDERS
P60HL 15996 06 0005 Cincinnati comprehensive sickle
cell center Factors precipitating crises (human)
POlHL-16910 05 0007 Regulation of the peripheral
circulation CNS Behavioral influences on circulation
(baboons)
** ROlHL-19343-03 Behavioral influences on cardiac
contractility (monkeys)
** ROIHL 19567 03 Impact of emotion on coronary arteries
(human)
ROlHL-21318-02 Mechanisms of emotions' asthma
triggering effect (human)
PSYCHOLOGY, EMOTIONS, ANGER
ROlHL-17706-04 Psychosocial hypertension,
catecholamines and drugs (mice)
PSYCHOLOGY, EMOTIONS, ANXIETY
P50HL-18318 03 0012 Pathogenesis and complications of
hypertension - Behavioral factors In hypertension (human)
ROlHL-18589-03 Psychosocial factors and outcome in
coronary disease (human)
ROIHL- 19204-03 Environmental factors m hypertension
(Rhesus monkeys)
ROlHL-19567-03 Impact of emotion on coronary arteries
(human)
ROlHL-21426-02 Learned heart rate control (human)
ROlHL-22378-01 Psyco-somatic predictors of CHO in
adolescence (human)
ROlHL-22809-01 Coronary-prone behavior and
cardiovascular reactivity (human)
PSYCHOLOGY, EMOTIONS, DEPRESSION
ROlHL-17706-04 Psychosocial hypertension.
catecholamines and drugs (mice)
ROlHL-18589-03 Psychosocial factors and outcome in
coronary disease (human)
ROlHL-19567-03 Impact of emotion on coronary arteries
(human)
ROlHL-22065-01 Intractability, medication, and coping
styles in asthma (human)
PSYCHOLOGY, EMOTIONS, EMPATHY
** R25HL-18418-03 Role of a supporting partner in
adherence (human)
PSYCHOLOGY, HABITS, SMOKING
SEE ALSO CONSUMER PRODUCTS. TOBACCO AND TOBACCO
PRODUCTS
SEE ALSO PYRIDINES. NICOTINE
** ROlHL-01803-23 0011 Arteriosclerosis, glomerulonephritis.
rheumatic fever - Immunopathologic consequences of
cigarette smoking (human, rabbits, plants)
** ROlHL-01803-23 0021 Arteriosclerosis, glomerulonephritis.
rheumatic fever - Induction of IgE antibodies to antigen
from tobacco and cigarette smoke (rabbits)
POlHL-03 174-23 0010 Mechanisms of acute vascular
reaction to injury - Search for mutagens In the human
blood (bacteria, animals)
ROlHL-03429-18 Central nervous system and coronary
heart disease (human)
POlHL-08974-14 0005 Natural and experimental
atherosclerosis - Atherosclerosis, coronary heart disease
and sudden death (human)
POlHL-08974-14 0028 Natural and experimental
atherosclerosis - Geographic pathology of atherosclerosis
and coronary heart disease (human)
ROlHL-09914-13 The myocardium In diabetes mellitus
(dogs, monkeys)
ROlHL-10009-13 Regional lung function in man
POlHL-10539-12 0068 Pathophysiology of circulation ■
Acute and chronic cardiomyopathies (mice, dogs, hamsters,
human)
ROlHL-10622-12 Volumes and compliance of pulmonary
circulation (human, dogs)
ROlHL-12833-09 Genetic and environmental Influences on
lung disease (human)
ROlHL-13036-08 Coronary thrombosis -Effects on
myocardium and In vivo detection (dogs, monkeys)
ROlHL-13824-06 Defense mechanisms in pathogenesis of
emphysema (human, dogs)
P50HL-14136-07 0009 Pulmonary SCOR-Airways
obstructive diseases - Tuscon epidemiological study of
airways obstructive disease (human)
(contd)
'Excludes routine methodology OR covers only general projects viliich preclude Indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for Investigator's name and grant number.
^^'
W^&^
PSY
444
PSY
P50HL-14136-07 0016 Pulmonary SCOR-Aitways
obstructive diseases - Environmental factors in airways
obstructive diseases (human)
P50HL14153-07 0001 Johns Hopkins Lung Center-
Chronic diseases of airways ■ Genetic and environmental
factors in chronic pulmonary disease (human)
P50HL1415307 0010 Johns Hopkins Lung Center-
Chronic diseases of airways - Risk factors for airways
obstruction in a rural community (human)
P50HL-14212-07 0004 Correlated studies of pulmonary
fibrosis - Collagen metabolism in lung tissue and lung
cells (human, animal)
P50HL-14212-07 0006 Correlated studies of pulmonary
fibrosis ' Alveolar macrophage physiology (human, rodents.
rabbits)
P50HL14212-07 0007 Correlated studies of pulmonary
fibrosis - Protein metabolism in alveolar macrophages
(rabbits, guinea pigs, human)
P50HL1421207 0012 Correlated studies of pulmonary
fibrosis ' Inorganic particulates in tobacco, smoke and
lungs of cigarette smokers (human)
ROlHL-14262-07 Leukocyte proteases and their lung
targets (human, dogs, rabbits)
ROlHL-14378-07 Lipemias and reconstructive cardiac
surgery (human)
ROlHL-14700-05 Humoral and lung protease-antiprotease
role in obstructive disease (human)
P50HL-15103-07 0001 A/S SCOR-Early natural history of
arteriosclerosis - Clinical research -Bogalusa heart study
(children)
ROlHL-15174-06 CV disease epidemiology-Second
generation studies (human)
POlHL-15194-07 0024 Pathophysiology of
cardiopulmonary dysfunction - Distribution of ventilation-
Airflow limitation in COLD (human)
R01HL1602905 Bio-organic chemistry of ozone, nitrogen
dioxide and tobacco smoke
POlHL-16118-06 0004 Study of emphysema - Metabolic
activity of pulmonary connective tissue (human, hamsters)
ROlHL-16463-05 Localization of airways obstruction and
responses
POlHL-16748-05 0006 Cellular and immunological basis
of pulmonary diseases - Sarcoidosis -Studies with bronchial
lavage (human)
ROlHL-16774-04 Genetic epidemiology of hyperlipemia
(Honolulu)
P60HL-17269-04 0042 National heart and blood vessel
research and demonstration center ■ Social-psychological
smoking deterrents in schools
P60HL1729204 0003 Vermont Lung Center ■ Subclinical
pulmonary disease in a rural environment (human)
The impact of stress on coronary heart
Cardiovascular fitness and other risk
ROl ML- 17 580-04
disease (men)
R01HL18235-03
factors (human)
ROlHL-18467-03 Fingertip blood flow in normals and
Raynaud's disease (human)
ROlHL-18632-02 Epidemiologic study of chronic lung
disease
ROlHL-191 18-03 Measurement of airways mechanics
(human, dog)
P50HL19170-02 0001 Harvard pulmonary SCOR -Chronic
diseases of the airways - Natural history, reversibility of
pulmonary abnormalities in smokers (human)
ROlHL-19237-03 Obstructive lung disease and alveolar
macrophages (human, animals)
P50HL-19362-02 A/S SCOR -Atherosclerosis in nonhuman
primates
P50HL-19362-02 0006 A/S SCOR-Atherosclerosis in
nonhuman primates - Effects of cigarette smoking on
atherosclerosis (baboon)
P50HL19362-02 0007 A/S SCOR-Atherosclerosis in
nonhuman primates - Behavior type, cigarette smoking and
atherosclerosis (baboon)
P50HL- 19362-02 0008 A/S SCOR-Atherosclerosis in
nonhuman primates - Lung structure and function in
cigarette smoking (baboon)
POlHL-19717-02 0043 Response of the lung to injury -
Asbestosis as a model of usual interstitial pneumonia
(human)
POlHL-19737-02 0009 Cellular and molecular aspects of
respiratory physiology - Regulation of tissue oxygen tension
and body carbon monoxide stores (human, dogs)
ROlHL-19839-09 Factors in youth predisposing to chronic
diseases (former college students)
ROlHL-19858-03 UMMC -Blood pressure precursors and
consequences (human)
ROlHL-19984-02 Blood pressure and immunogenetic
factors in the young (human)
ROlHL-20179-02 Epidemiology of sudden cardiac death
among v«omen
ROlHL-2038103
disease (human)
ROlHL-2066202 Physical activity, fitness and
epidemiology of CHD
ROlHL-20675-02 Alveolar macrophage function in man
ROlHL-20847-02 Respiratory neurochemical control
(human, goats)
ROlHL-20875-02 Chronic obstructive pulmonary disease -
Familial/genetic (human)
POlHL-20994-02 Dynamics of neutrophil elastasc in the
lung
Long term study of diabetic vascular
POlHL-20994-02 0002 Dynamics of neutrophil elastase in
the lung - Neutrophil and neutrophilic elastase in human
lungs
POlHL-20994-02 0003 Dynamics of neutrophil elastase in
the lung - Neutrophil elastase flux in models of lung
disease (dogs)
POlHL-20994-02 0008 Dynamics of neutrophil elastase in
the lung - Structure-function correlation In experimental
emphysema (human, dogs)
ROlHL-21010-02 Glycemia. other traits and CV death in
40.000 persons
ROlHL-21307-01 Risk reduction and exercise fitness in a
population
ROlHL-21352-02 Community studies of obstructive lung
disease (human)
R18HL-21906-01 Stanford five city multifactor risk
reduction study
ROlHL-21971-01 Atherosclerotic disease and risk factors
in twins (human)
ROlHL-22123-02 The role of the red cell in diabetic
atherosclerosis (human)
** ROlHL-22472-01 Smoking risk-factor reduction-
Maintenance strategies (human)
ROlHL-22528-02 Early risk predictors for chronic
pulmonary disease (human)
ROlHL-22623-01 Polyamines cellular mediators of
atherogenesis (human)
** R23HL-22947-01 Experimental systems to improve youth
behavior (smoking prevention)
** NOlHR-32900-09 Pilot study to standardize the
measurement of closing volume' (human)
** NOlHR-32902-07 Pilot study to standardize the
measurement of closing volume (human)
** NOlHR-32903-11 Pilot study to standardize the
measurement of 'closing volume' (human)
NOlHV-22971-07 Prevention of coronary heart disease
(human)
NOlHV-22976-07 Multiple risk factor intervention trial,
prevention of coronary heart disease
NOlHV-22977-08 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22979-07 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22980-06 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22981-10 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22982-07 Intervention trial for prevention of
coronary heart disease (human)
N01HV-22983-07 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-33101-06 Development and conduct of a multiple
risk factor intervention trial (human)
NOlHV-33105-09 Intervention trial for prevention of
coronary heart disease (human)
NOlHV-33106-06 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-33108-04 Prevention of coronary heart disease
(human)
NOlHV-33109-04 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-331 10-04 Prevention of coronary heart disease
(human)
NOlHV-42929-08 Risk factor intervention trial for the
prevention of CHD (human)
NOlHV-42930-09 Risk factor intervention trial for the
prevention of CHD (human)
NOlHV-42931-07 Risk factor intervention trail for the
prevention of CHD (men)
NOlHV-42932-05 Risk factor intervention trial for the
prevention of CHD (human)
NOIHV-42933-09 Multiple risk factors in coronary heart
disease (human)
PSYCHOLOGY, LEARNING
SEE ALSO EDUCATION, PROGRAMMED INSTRUCTION
SEE ALSO PSYCHOLOGY, CONDITIONING
** ROlHL-21532-02 Cardiovascular homeostasis and learning
(frogs, rats, human)
PSYCHOLOGY, LEARNING, HABITUATION
P50HL-142 14-07 0013 Newborn lung center for hyaline
membrane disease - Developmental outcome of children
who had HMD as infants
ROlHL-19974-02 Psychologic-behavioral influences on
heart pathology (rats)
PSYCHOLOGY, LEARNING, REINFORCEMENT
SEE ALSO PSYCHOLOGY, CONDITIONING, REINFORCEMENT
R25HL-18406-03 Adherence to hypertensive medical
regimens (human)
R25HL-184 14-03 Hypertension -Family strategies for
patient adherence
PSYCHOLOGY, LEARNING, TRANSFER
ROlHL-21426-02 Learned heart rate control (human)
PSYCHOLOGY, MENTAL PROCESSES (GENERAL)
SEE ALSO PSYCHOLOGY, COGNITION
" POlHL-08899-14 0046 Tolerance to respiratory gases in
health and disease - Studies in senile elderly individuals
PSYCHOLOGY, MOTIVATION
SEE ALSO PSYCHIC ACTIVITY LEVEL
SEE ALSO PSYCHOLOGY, BEHAVIOR, GOAL-STRIVING
SEE ALSO PSYCHOLOGY. PERFORMANCE
R25HL-1705e-01 Improving patient compliance through
nursing action
R25HL-18406-03 Adherence to hypertensive medical
regimens (human)
R25HL-18414-03 Hypertension -Family strategies for
patient adherence
PSYCHOLOGY, MOTIVATION, REWARDS AND
NON-REVt^ARDS
ROlHL-22472-01 Smoking risk-factor reduction-
Maintenance strategies (human)
PSYCHOLOGY, PERFORMANCE
SEE ALSO HEALTH SCIENCES PROFESSIONS, HEALTH
PERSONNEL PERFORMANCE
M POlHL-08899-14 Tolerance to respiratory gases in health
and disease
Tolerance to respiratory gases in
Oxygen effects upon CNS and sensory
POlHL-08899 14 0043
health and disease
functions (human)
POlHL-08899-14 0044
health and disease
Tolerance to respiratory gases in
Influence of high oxygen pressures on
cognition and performance
POlHL-08899-14 0064 Tolerance to respiratory gases in
health and disease - Narcotic effects of inert gases on
functional systems (rats)
PSYCHOLOGY, PERFORMANCE, ACADEMIC
ACHIEVEMENT
SEE ALSO EDUCATION, TRAINING LEVEL
P60HL-15158-07 0010 Comprehensive sickle cell center -
Tutorial service for sickle cell anemia patients
" P60HL-15996-06 0004 Cincinnati comprehensive sickle
cell center - School adjustment of sickle cell patients
P50HL-19187-02 0007 Pediatric pulmonary SCOR-Hyaline
membrane disease Follow-up study-Infants with hyaline
membrane disease (human)
ROlHL-22378-01 Psyco-somatic predictors of CHD in
adolescence (human)
PSYCHOLOGY, PERFORMANCE, INTELLIGENCE
SEE ALSO MENTAL RETARDATION
P50HL-142 14-07 0013 Newborn lung center for hyaline
membrane disease - Developmental outcome of children
who had HMD as infants
P50HL-19187-02 0007 Pediatric pulmonary SCOR-Hyaline
membrane disease - Follow-up study-Infants with hyaline
membrane disease (human)
PSYCHOLOGY, PERFORMANCE, SUCCESS-
FAILURE
ROlHL-22809-01 Coronary-prone behavior and
cardiovascular reactivity (human)
PSYCHOLOGY, PERSONALITY
SEE ALSO PSYCHOLOGY. AHITUDES (AND RELATED)
SEE ALSO PSYCHOLOGY. BEHAVIOR
SEE ALSO PSYCHOLOGY. PERFORMANCE. INTELLIGENCE
R01HL-18776-04 Prevention of acute and fatal
cardiovascular disease (human)
ROlHL-19929-03 High blood pressure in the young.
prevalence and precursors (human)
ROlHL-22065-01 Intractability, medication, and coping
styles in asthma (human)
ROlHL-23078-01 Psychosocial stress and sudden coronary
death (human)
PSYCHOLOGY, PERSONALITY, LIFE STYLE
ROlHL-04697-17 International heart disease epidemiology
(human)
ROlHL-18589-03 Psychosocial factors and outcome in
coronary disease (human)
** ROlHL-19839-09 Factors in youth predisposing to chronic
diseases (former college students)
ROlHL-20005-03 Factors in blood pressure levels of
children
ROlHL-20910-02 The alternative diet for coronary disease
prevention (human)
ROlHL-22472-01 Smoking risk-factor reduction-
Maintenance strategies (human)
PSYCHOLOGY, PERSONALITY DEVELOPMENT,
SELF-CONCEPT
P60HL-15160-07 0003 Center for sickle cell disease -
Genetic counseling in hemoglobinopathies -Dimensions.
effectiveness
P60HL- 15996-06 0004 Cincinnati comprehensive sickle
cell center - School adjustment of sickle cell patients
R23HL-21954-01 Exercise conditioning in patients with
cystic fibrosis
PSYCHOLOGY, PERSUASION
SEE ALSO PSYCHOLOGY. SUGGESTION
P60HL-17269-04 0042 National heart and blood vessel
research and demonstration center - Social-psychological
smoking deterrents in schools
PSYCHOLOGY, SUGGESTION
SEE ALSO PSYCHOLOGY. PERSUASION
ROlHL-21318-02 Mechanisms of emotions' asthma
triggering effect (human)
(cantd)
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level-
**Ohented significantly to above subject.
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
PSY
PSYCHOIOOY, SUGGESTION, HYPNOSIS
•• P50HI 183?304 0047 SCOR hypertension center
Transcendental meditation and sell hypnosis Hypertension
tieatment (human)
PSYCHOLOGY ABNORMAL, EMOTIONAL
DISORDERS
SEE Also PSYCHOLOGY. EMOTIONS. DEPRESSION
ROIHL 20725 02 Mechanisms and cellular (unctions ol ion
transport
PSYCHOLOGY ABNORMAL, MENTAL DISORDERS
(GENERAL)
SEE ALSO MENTAL RETARDATION
SEE ALSO METABOLIC DISORDERS INBORN.
HEPATOLENTICULAR DEGENERATION
ROIHL 18994 03 Substance P -Occurrence, pharmacology
and physiology (mammals non-human, human)
ROIHL 2017902 Epidemiology ot sudden cardiac death
among women
PSYCHOLOGY ABNORMAL, MENTAL DISORDERS
CHEMOTHERAPY
SEE ALSO PSYCHOPHARMACOLOGY
ROlHL-20725-02 Mechanisms and cellular functions of ion
transport
PSYCHOLOGY DEVELOPMENTAL (CHILD MENTAL
DEVELOPMENT)
SEE CHILD MENTAL DEVELOPMENT
PSYCHOLOGY EDUCATIONAL (GENERAL)
SEE ALSO PSYCHOLOGY. LEARNING
SEE ALSO PSYCHOLOGY. PERFORMANCE
P60HL-1729204 0008 Vermont Lung Center - Respiratory
physiology-Teaching, learning and auditing problem-solving
skills
PSYCHOLOGY SOCIAL (SEE ALSO SOCIAL..)
SEE ALSO FAMILY
SEE ALSO PSYCHOSOCIAL ISOUTION-DEPRIVATION
P50HL-15103-07 0001 A/S SCOR-Early natural history of
arteriosclerosis - Clinical research-Bogalusa heart study
(children)
** P50HL-18318-03 0012 Pathogenesis and complications of
hypertension - Behavioral factors in hypertension (human)
R25HL-18406-03 Adherence to hypertensive medical
regimens (human)
** ROlHL-20159-03 Genetic epidemiology of precursors of
hypertension (human)
PSYCHOLOGY SOCIAL, COMPETITION
ROlHL-21319-02 Interpersonal stress and coronary-prone
behavior (human)
PSYCHOLOGY SOCIAL, GROUP PROCESSES
SEE ALSO SOCIAL GROUPS
ROlHL-17706-04 Psychosocial hypertension,
catecholamines and drugs (mice)
PSYCHOLOGY SOCIAL, GROUP PROCESSES,
PEER GROUPS
R25HL-18424-03 Blood pressure education in an industrial
setting (human)
R23HL-22947-01 Experimental systems to improve youth
behavior (smoking prevention)
PSYCHOLOGY SOCIAL, GROUP PROCESSES,
SOCIAL DOMINANCE
P50HL-19362-02 0007 A/S SCOR-Atherosclerosis in
nonhuman primates - Behavior type, cigarette smoking and
atherosclerosis (baboon)
PSYCHOLOGY SOCIAL, INTERPERSONAL
RELATIONS
SEE ALSO HEALTH CARE SERVICES. PATIENT-PROFESSIONAL
REUTIONS
ROlHL-17706-04 Psychosocial hypertension.
catecholamines and drugs (mice)
P50HL-18318-03 0012 Pathogenesis and complications of
hypertension - Behavioral factors in hypertension (human)
ROlHL-20724-01 Behavioral consequences of hypertension
(human)
ROlHL-21319-02 Interpersonal stress and coronary-prone
behavior (human)
ROlHL-23078-01 Psychosocial stress and sudden coronary
death (human)
PSYCHOLOGY SOCIAL, INTERPERSONAL
RELATIONS, DIADIC INTERACTION
** R25HL-18418-03 Role of a supporting partner in
adherence (human)
PSYCHOLOGY SOCIAL, SOCIAL ADJUSTMENT
SEE ALSO PSYCHOLOGICAL ADAPTATION. EMOTIONAL
ADJUSTMENT
ROlHL-15790-06 Follow-up study of acute coronary heart
attacks (human)
** P60HL-15996-06 0004 Cincinnati comprehensive sickle
cell center - School adjustment of sickle cell patients
PSYCHOLOGY SOCIAL, SOCIAL BEHAVIOR
P50HL-18318-03 0012 Pathogenesis and complications of
hypertension - Behavioral factors in hypertension (human)
445
PiOML 19362 02 0003 A/S SCOR Alhorosclerosij in
nonhuman primates Heritability ol characters related to
atherosclerosis (baboons)
PbOHL 19362 02 000/ A/S SCOR Atherosclerosis in
nonhuman primates Behavior type, cigarette smoking and
atherosclerosis (baboon)
P50HL 19362 02 0014 A/S SCOR Atherosclerosis in
nonhuman primates Core laboratory Behavior observation
and manipulation (baboon)
PSYCHOLOGY SOCIAL, SOCIAL CONFORMITY
P60HL 17269 04 0042 National heart and blood vessel
research and demonstration center Social-psychological
smoking deterrents in schools
PSYCHOMETRICS
P50HL 15103 07 0001 A/S SCOR-Early natural history of
arteriosclerosis Clinical research-Bogalusa heart study
(children)
ROlHL-20637 02 Recovery after heart surgery -Bio-
behavioral factors (human)
PSYCHOMOTOR FUNCTION
POlHL-08899 14 0043
health and disease
functions (human)
POlHL-08899 14 0045
health and disease
POIHL 08899-14 0064
health and disease
Tolerance to respiratory gases in
Oxygen effects upon CNS and sensory
Tolerance to respiratory gases in
Studies in normal subjects
Tolerance to respiratory gases in
Narcotic effects of inert gases on
functional systems (rats)
** POlHL-08899-14 0065 Tolerance to respiratory gases in
health and disease - Adaptation and effects of narcotic
gases exposure (human)
** POlHL-08899-14 0066 Tolerance to respiratory gases in
health and disease - Neurophysiological effects of inert
gases in man
ROlHL-20724-01 Behavioral consequences of hypertension
(human)
PSYCHOMOTOR FUNCTION, TRACKING TASK
POlHL-16878-05 0001 Control of ventilation in health
and disease - Ability of asthmatics to detect added
resistive and elastic loads
PSYCHOMOTOR FUNCTION, VISUAL TRACKING
" POlHL-08899-14 0067 Tolerance to respiratory gases in
health and disease - Inert gas influences upon visual
function in man
PSYCHOPHARMACOIOGICAL AGENTS,
ANTIDEPRESSANTS
ROlHL-17487-04 Adrenergic-vasoregulation interactions in
hypertension (human)
PSYCHOPHARMACOLOGICAL AGENTS,
HYPNOTICS AND SEDATIVES
POlHL-14985-07 0009 Adaptation to hypoxia - Influence
of chemosensitivity on control of breathing during sleep
(human, dogs)
PSYCHOPHARMACOLOGICAL AGENTS,
NARCOTICS
ROlHL-15659-05 Dynamic isolation studies of control of
respiration (human)
ROlHL-16022-05 Determinants of the ventilatory response
to hypoxia (goats, cats)
** ROlHL-17954-03 Narcotics and the circulation (human,
dogs, pigs, monkeys)
PSYCHOPHARMACOLOGICAL AGENTS,
PSYCHOTROPIC DRUGS (GENERAL)
" P01HL-12738-10 0065 Physiologic pharmacology and its
clinical applications - Psychotheropeutic drugs and
cardiovascular system (human, rats)
PSYCHOPHARMACOLOGICAL AGENTS,
TRANQUILIZERS
ROlHL-12971-15 Reactions of alkoloids and their analogs
ROlHL-13909-27 Physiochemistry and immunology of
macromolecules
** POlHL-14388-07 0159 Regulation of the circulation In
pathological states • Early drug and diet interventions and
blood pressure development (rats)
ROlHL-17958-04 Circulatory effects of operant
cardiovascular control (baboons)
ROlHL-20861-01 Cardio-respiratory-renal stress reactions
(dogs)
PSYCHOPHARAAACOLOGY
SEE ALSO NEUROPHARMACOLOGY
SEE ALSO PSYCHOLOGY ABNORMAL, MENTAL DISORDERS
CHEMOTHERAPY
** POlHL-12738-10 0065 Physiologic pharmacology and its
clinical applications - Psychotheropeutic drugs and
cardiovascular system (human, rats)
" ROlHL-13909-27 Physiochemistry and immunology of
macromolecules
ROlHL-22547-01 Behavioral treatment of Raynaud's
disease (human)
PSYCHOPHYSIOLOGIC DISORDERS
SEE ALSO BEHAVIORAL MEDICINE
SEE ALSO GASTROINTESTINAL DISORDERS. PEPTIC ULCER
SEE ALSO PSYCHOLOGIC STRESS
PSY
ROIHL 15/90 06 follow up iludy ol acute coronary heart
attacks (human)
"" P50HI 18318 03 0012 Pathogeneiu and compliialioni ol
hypertension Behavioral (actors in hyperteniion (human)
ROlHt 18589 03 Psychosocial factors and outcome in
coronary disease (human)
•* ROIHL 18814 03 Behavioral tactics (or clinical cardiac
control (human)
ROIHL 18823 02 Physiological correlates of conditioned
blood pressure (human)
•• ROIHL 19974 02 Psychologic behavioral induences on
heart pathology (rats)
ROIHL 20655-02 Autonomic predictors o( hypertension in
children
*• ROIHL 2131802 Mechanisms o( emotions' asthma
triggering effect (human)
ROIHL 2132302 Raynaud's disease and temperature self
regulation (human)
ROIHL 21426-02 Learned heart rate control (human)
R01HL21427 02 Behavioral changes in post intarction
patients
ROIHL 22021 01 Asthma in families - Behavior analysis of
family interaction pattern
ROlHL-22065-01 Intractability, medication, and coping
styles in asthma (human)
** ROlHL-22378-01 Psycosomatic predictors of CHO in
adolescence (human)
** ROlHL-2274001 Behavior and cardiovascular disease -
Basic mechanisms (human)
PSYCHOPHYSIOLOGY
SEE PSYCHOBIOLOGY. PSYCHOPHYSIOLOGY
PSYCHOSIS, DEPRESSIVE, REACTIVE PSYCHOTIC
DEPRESSION
ROlHL-2 1426-02 Learned heart rate control (human)
PSYCHOSIS, SENILE
SEE BRAIN DISORDERS, CEREBRAL ATROPHY DIFFUSE,
SENILE DEMENTIA
PSYCHOSOCIAL FACTORS IN HYPERTENSION
SEE CARDIOVASCULAR DISORDERS, HYPERTENSION
(SYSTEMIC), ENVIRONMENT-ASSOCIATED
PSYCHOSOCIAL ISOLATION-DEPRIVATION
" ROlHL-17706-04 Psychosocial hypertension.
catecholamines and drugs (mice)
** ROlHL-18589-03 Psychosocial factors and outcome in
coronary disease (human)
" ROlHL-20384-09 Social stimulation. RNA and
cardiovascular disease (animals)
PSYCHOSOMATIC DISORDERS
SEE PSYCHOPHYSIOLOGIC DISORDERS
PSYCHOTHERAPEUTIC DRUGS
SEE PSYCHOPHARMACOLOGICAL AGENTS. PSYCHOTROPIC
DRUGS (GENERAL)
PSYCHOTHERAPY, BEHAVIOR MODIFICATION
SEE ALSO PSYCHOTHERAPY. DESENSITIZATION
R25HL-17056-01 Improving patient compliance through
nursing action
P60HL-17269-04 0042 National heart and blood vessel
research and demonstration center - Social-psychological
smoking deterrents in schools
P60HL- 17269-04 0043 National heart and blood vessel
research and demonstration center - Dietary modification-
Effect on cardiovascular risk parameters (human)
P60HL-17269-04 0047 National heart and blood vessel
research and demonstration center - Evaluation of
competency-based educational model
ROlHL-19568-03 Hypertension -Analysis of drug and
behavioral therapies (human)
R01HL-20910-02 The alternative diet for coronary disease
prevention (human)
** ROlHL-21427-02 Behavioral changes in post infarction
patients
R23HL-22345-02 Behavioral cardiovascular compliance
strategies
R23HL-22345-02 0001 Behavioral cardiovascular
compliance strategies - Long term modification of dietary
patterns (human)
R23HL-22345-02 0002 Behavioral cardiovascular
compliance strategies ■ Compliance with antihypertensive
medication regimens (human)
M
ROlHL-22547-01
disease (human)
NOlHR-72974-01
children
NOlHV-72983-00
Behavioral treatment of Raynaud's
Self-management systems for asthmatic
Nutrition counseling in hyperlipidemia
PSYCHOTHERAPY, DESENSITIZATION
ROlHL-21426-02 Learned heart rate control (human)
ROlHL-22021-01 Asthma in families- Behavior analysis of
family interaction pattern
PSYCHOTHERAPY, FAMILY THERAPY
R23HL-22345-02 0001 Behavioral cardiovascular
compliance strategies - Long term modification of dietary
patterns (human)
R23HL-22345-02 0002
compliance strategies
medication regimens (human)
Behavioral cardiovascular
Compliance with antihypertensive
(contd)
•Excludes routine methodology OR covers only general projects which preclude i
••Oriented significantly to above subject.
indexing at the specific level.
M Grant has subprajects describing specific research aspects.
See Appendix for investigator's name and grant number.
PSY
446
PUR
PSYCHOTHERAPY, GROUP THERAPY
SEE ALSO MENTAL HEALTH SERVICES, COUNSELING, GROUP
POlHL-1053912 0031 Pathophysiology of circulation •
Post myocardial infarction care -Psychological aspects
(human)
NOlHR-7297401 Self-management systems for asthmatic
children
PSYCHOTROPIC DRUGS
SEE PSYCHOPHARMACOLOGICAL AGENTS, PSYCHOTROPIC
DRUGS (GENERAL)
PTC FACTOR
SEE BLOOD COAGULATION, FACTOR IX
PTFE
SEE PLASTICS. FLUOROCARBON POLYMERS
PTEROYLGLUTAMIC ACID
SEE FOLIC ACID
PUBERTY
SEE CHILD DEVELOPMENT, PUBERTY
PUBERTY (ANIMAL)
SEE AGE (ANIMAL). PUBERTY
PUBLIC ASSISTANCE, MEDICAL
SEE HEALTH ECONOMICS. HEALTH CARE COSTS-FINANCING,
MEDICAL INDIGENCY
PUBLICATIONS
P01HL-Oe312-17 0051 Surgical cardiology - Diuretic
therapy on myocardial electrolyte composition and water
content (human)
POlHL-08899-14 0089 Tolerance to respiratory gases in
health and disease - Decompression by applications of
optimal control theory
PUBLICATIONS, ATLASES
** NO lHR-629 10-02 Fibroprotein networks of pulmonary
alveolar wall (human)
PUBLICATIONS, HANDBOOK
R23HL-22947-01 Experimental systems to improve youth
behavior (smoking prevention)
** NOlHV-72941-02 Therapy to protect ischemic myocardium-
Clinical tests
** NOlHV-72942-02 Therapy to protect ischemic myocardium-
Clinical tests
PUBUCATIONS, LITERATURE SURVEY
** POIHL- 14388-07 0195 Regulation of the circulation in
pathological states - General review of potential
pathophysiologic factors in spontaneous hypertension
PUERILE
SEE CHILDREN
PUERTO RICO
SEE GEOGRAPHICAL SITES, UNITED STATES, PUERTO RICO
PUFFER FISH TOXIN
SEE TOXICOLOGY, ANIMAL POISONS, TETRODOTOXIN
PULMONARY AIRWAY RESISTANCE NORMAL
SEE RESPIRATORY FUNCTION, RESPIRATORY AIRWAY
PRESSURES
PULMONARY ALVEOLAR PROTEINOSIS
SEE RESPIRATORY DISORDERS, PULMONARY ALVEOUR
PROTEINOSIS
PULMONARY ARTERY
SEE RESPIRATORY CIRCULATION, PULMONARY ARTERY
PULMONARY CIRCULATION
SEE RESPIRATORY CIRCULATION, PULMONARY CIRCULATION
PULMONARY CIRCULATORY OBSTRUCTION
SEE RESPIRATORY CIRCULATORY DISORDERS, PULMONARY
CIRCULATORY OBSTRUCTIONS
PULMONARY DIFFUSION
SEE RESPIRATORY FUNCTION, PULMONARY DIFFUSION
PULMONARY DISORDERS
SEE RESPIRATORY DISORDERS, LUNG DISORDERS (GENERAL)
PULMONARY EDEMA
SEE RESPIRATORY DISORDERS, PULMONARY EDEMA
PULMONARY EMPHYSEMA
SEE RESPIRATORY DISORDERS, BRONCHITIS CHRONIC AND
EMPHYSEMA
PULMONARY FIBROSIS AND GRANULOMAS
SEE RESPIRATORY DISORDERS, PULMONARY FIBROSIS AND
GRANULOMAS
PULMONARY HEART DISEASE
SEE RESPIRATORY CIRCULATORY DISORDERS, PULMONARY
HEART DISEASE
PULMONARY HYPERTENSION
SEE RESPIRATORY CIRCUWTORY DISORDERS, PULMONARY
HYPERTENSION
PULMONARY HYPOXIA
SEE RESPIRATORY GAS LEVELS, HYPOXIA, RESPIRATORY
PULMONARY IMMATURITY, NEWBORN
SEE CONGENITAL ABNORMALITIES, RESPIRATORY DISTRESS
SYNDROME
PULMONARY INSUFFICIENCY (GENERAL)
SEE RESPIRATORY DISORDERS, RESPIRATORY INSUFFICIENCY
(GENERAL)
PULMONARY INSUFFICIENCY LUNG NEWBORN
SEE CONGENITAL ABNORMALITIES, RESPIRATORY DISTRESS
SYNDROME
PULMONARY INSUFFICIENCY POST-TRAUMATIC
SEE RESPIRATORY DISORDERS. RESPIRATORY
INSUFFICIENCY, SHOCK LUNG
PULMONARY ISCHEMIA AND HYPOXIA
SEE RESPIRATORY CIRCULATORY DISORDERS, PULMONARY
ISCHEMIA AND HYPOXIA
PULMONARY LAVAGE
SEE RESPIRATORY ASSIST AND OXYGEN ADMINISTRATION.
PULMONARY UVAGE
PULMONARY STRETCH RECEPTORS
SEE RESPIRATORY SYSTEM, PULMONARY STRETCH
RECEPTORS
PULMONARY SURFACTANT
SEE RESPIRATORY SYSTEM, PULMONARY SURFACTANT
PULMONARY VALVE
SEE HEART, VALVES, PULMONARY VALVE
PULMONARY VALVE STENOSIS
SEE HEART DISORDERS, VALVULAR, PULMONARY VALVE
STENOSIS
PULMONARY VEINS
SEE RESPIRATORY CIRCULATION, PULMONARY VEINS
PULMONARY VENTILATION
SEE RESPIRATORY FUNCTION, PULMONARY VENTILATION
PULSE PRESSURE WAVES
SEE CARDIOVASCULAR FUNCTION, VASOMOTION, PULSE
PRESSURE WAVES
PUMP-OXYGENATOR
SEE CARDIOVASCULAR SURGERY, CIRCULATORY ASSIST,
HEART MECHANICAL EXTRACORPOREAL
PUMPLESS BLOOD OXYGENATORS
SEE CARDIOVASCULAR SURGERY, CIRCULATORY ASSIST,
BLOOD OXYGENATORS
PUPILLOGRAPHY
SEE EYE DISORDERS DIAGNOSIS, PUPILLOGRAPHY*
PURE LINES
SEE GENETICS, GENOTYPES, HOMOZYGOTES
SEE GENETICS, POPULATION GENETICS, INBREEDING
PURINE NUCLEOSIDES
ROlHL-20286-02 Interventions to improve cardiac function
in ischemia (dogs)
PURINE NUCLEOSIDES, ADENINE NUCLEOSIDES
ROlHL-202 78-02 Cellular mechanisms of renin secretion
(rats)
PURINE NUCLEOSIDES, ADENINE NUCLEOSIDES,
ADENOSINE
ROlHL-05883-18 0002 Reflex control of resistance and
capacitance vessels - Adenosine, adenine nucleotides and
vascular smooth muscle (dog)
POlHL-10342-13 0019 The integrated function of
respiration and circulation - Cerebral circulation and
metabolism (dogs)
** ROlHL-10384-13 Blood flow and nucleotide metabolism
(animals)
ROlHL-11906-11 Comparative study of heart function
(cats, rats, hedgehogs, squirrels)
ROlHL-12792-09 Local control of the microcirculation
(hamsters, rats)
P50HL-14217-08 0058 Specialized center of research in
thrombosis - Mechanisms of induction and inhibition of
platelet reaction (human, pig)
POlHL-14985-07 0012 Adaptation to hypoxia - Direct
effect of hypoxia on pulmonary vascular smooth muscle
(rats, dogs)
•* P01HL15194-07 0018 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation,
metabolic demand and vasodilatory reserve (human, dogs)
POlHL-15194-07 0020 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation in
arteriographically normal arteries (human)
** ROlHL-164 12-04 Release of nucleosides from the ischemic
heart (human, dogs)
ROlHL-16760-05 Dynamic control of coronary blood flow
(dogs)
** P50HL-17651-04 0041 Ischemic heart disease specialized
center of research - Biochemical indices of ischemic injury
(guinea pig)
P50HL-1 7682-04 0020 Study of ischemic heart disease ■
Nucleotide and nucleoside metabolism in ischemic
myocardium
Studies of myocardial reactive hyperemia
Blood flow regulation in muscle (cats)
Regulation of neurotransmitter release by
Hypoxia-induced relaxation of vascular
'Excludes routine melhodak)(y OR covers only general projects which preclude indexing
"Onanted signrTicanthr to above subject.
ROlHL-17759-03
(dogs, human)
ROlHL-17932-04
** R01HL18601-01
adenosine (rats)
ROlHL-19082-01
smooth muscle
** ROlHL-19202-03 Adenosine, prostaglandins in relation to
coronary flow (guinea pigs)
" POIHL- 19242-02 0003 Study of vascular smooth muscle -
Vasoactive metabolites from vascular muscle and
parenchymal tissue (animal)
POlHL-19242-02 0004 Study of vascular smooth muscle -
Cyclic nucleotide metabolism in smooth muscle cultures
(human, rats)
POIHL- 19242-02 0007 Study of vascular smooth muscle -
NE release in and reactivity of vascular smooth muscle
(animals)
ROlHL-19370-03 Coronary capillary exchange-The effects
of ischemia (dogs, sheep)
** ROlHL-2078201 Coronary flow regulation by adenosine
(rats, dogs)
R23HL-21434-02 Intrinsic control of coronary blood flow by
chemicals (guinea pigs)
ROlHL-21872-01 Myocardial perfusion in the hypertrophied
heart (dogs)
** ROlHL-22828-01 Adenosine and catecholamine interaction
in the heart (rats)
R23HL-22975-01 Dynamics of autoregulation of muscle
blood flow (dogs)
ROlHL-23140-01 Determinants of irreversible ischemic
injury in heart (dog. rat)
PURINE NUCLEOSIDES, ADENINE NUCLEOSIDES,
DIMETHYL-3'-AMINO-3'-DEOXYADENOSINE
ROIHL- 16490-04 Structural basis of nephron filtration
(rats, rabbits)
PURINE NUCLEOSIDES, HYPOXANTHINE
NUCLEOSIDES, INOSINE
ROlHL-16412-04 Release of nucleosides from the ischemic
heart (human, dogs)
ROlHL-16931-04 Red cell storage and transfusion
(human, animals)
ROlHL-18489-03 Hemodynamic interactions of vasoactive
chemicals (rats)
ROlHL-23 140-01 Determinants of irreversible ischemic
injury in heart (dog, rat)
PURINE NUCLEOTIDES
ROlHL-18288-04 Intraoperative protection of the
myocardium (dogs, rats)
RClHL-22290-01 Cardiac energy metabolism and protein
synthesis (mice)
PURINE NUCLEOTIDES, ADENINE NUCLEOTIDES
ROlHL-02363-20 Kinetics of water and electrolytes in
shock (dogs, rats)
** ROlHL-05883-18 0002 Reflex control of resistance and
capacitance vessels - Adenosine, adenine nucleotides and
vascular smooth muscle (dog)
POlHL-06314-17 0047 Immunologic mechanisms in
cardiovascular disease - Role of intravascular coagulation
(human, animals)
P50HL-15061-07 0002 Response of lung to injury -
Oxidative metabolism, phospholipid synthesis, and response
to toxins (rats)
POIHL- 16833-04 0016 Hemoglobin and red cell system in
hemoglobinopathies - Calcium-indiced membrane damage
in Hb SS disease (human, animals)
ROlHL-16931-04 Red cell storage and transfusion
(human, animals)
** ROlHL-17372-03 Adenine nucleotide maintenance in the
ischemic heart (rats)
ROlHL-17736-04 Metabolic change during cardiac
ischemia (rats, dogs)
ROlHL-17759-03 Studies of myocardial reactive hyperemia
(dogs, human)
ROlHL-18038-03 Structure and function of heart
mitochondria (cattle)
ROlHL-20079-02 0002 Thromboresistant material -
Thromboresistant materials (sheep)
** ROlHL-20206-02 Carbohydrates-nucleotides and adrenergic
interactions (rabbits, cats, rats)
ROlHL-20818-02 Platelet storage at 22 degrees C
(human)
ROlHL-22281-01 Microprobe analysis and metabolite
levels of ischemic mycardium (dogs)
" ROlHL-23 153-01 Mechanisms of altered CA20 transport in
ischemic heart (dog, rabbit)
ROlHL-23205-01 Contraction of pulmonary vascular
smooth muscle (cat)
PURINE NUCLEOTIDES, ADENINE NUCLEOTIDES,
ADP
ROlHL-01974-24 Ion-pump in the erythrocyte (rabbits.
guinea pigs)
P01HL-06285-18 0178 Cardiovascular-respiratory
physiology and biochemistry - Biochemical regulation of
hypertrophy (rats, rabbits)
POlHL-06285-18 0200 Cardiovascular-respiratory
physiology and biochemistry - Medullary counter-current
system (animals)
(oontiO
atthespecificlevel.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
. -^>'lffHUDU«fHUi>
PUR
•* POIHL 06312 17 0052 Sut|ic»l cardiology Assay o(
metabolic vaiiablas ol tal h«ac1
P01HL06664 W 0040 Caidiopulmonaiy lunction in
ramediabla vascular disease The couplint of ion ttarsport
to metabolism (toads)
P50HI 142W 08 0051 Specialiied center of research in
thrombosis Microcirculation section (bat, hamster)
P50HL 1421708 0058 Specialized center ol research in
thrombosis Mechanisms ot induction and inhibition o(
platelet reaction (human. pi|)
•* ROIHI 1434407 Platelet function and adenine nucleotide
metabolism (human)
POIHL 1438807 0173 Rejulation ot the circulation in
pathological states Mechanisms ol cardiac myosin ATPase
ROIHL 14595 07 Primary disorders ol platelet lunction
(human, rats)
ROIHL 15335 06 The nature ol the collagen platelet
interaction (animals)
ROIHL 15692 07 Force and speed in skeletal and cardiac
muscle
ROIHL 15980-06 Reactions ot hemeproteins and oxygen
(cattle)
P50HL 17651 04 0041 Ischemic heart disease specialized
center of research ■ Biochemical indices of ischemic injury
(guinea pig)
R01HL1850203 Enzymatic regulation of platelet function
(human)
POIHL 1857603 0001 Thrombosis research program
project ■ Platelet damage from physical forces and
artificial surfaces (human)
R01HL18584-03 Effects of physical forces on platelets
(human)
PO1HL18827-02 0003 Platelet vessel wall interactions in
thrombogenesis - Tumor cell and platelets in
thrombogenesis and metastasis (human, animals)
P50HL1882803 0001 Specialized center of research in
thrombosis ■ Membrane biology and hemostasis (human)
P50HL18828-03 0004 Specialized center of research in
thrombosis ■ Membrane changes in platelet physiology-Role
of complement (mice, human)
ROlHL-20262-02 Cardiac glycosides and the mechanism
of the sodium potassium pump
ROlHL-204 11-03 Platelet tatty acid metabolism in
diabetes (rat, rabbit, guinea pig)
ROlHL-20787-02 Thromboxanes and prostaglandins-
Biochemical pharmacology (rabbits, human)
ROlHL-20956-02 Early events following stimulation of
human platelets
R23HL-2 1128-02 ATP utilization in platelet contractile
mechanisms (human, rabbits)
ROlHL-22231-02 Modulation of calcium control of cardiac
myofibrils (rats)
ROlHL-2273801 Role of bioelectric potentials in platelet
adherence (bats, rats, hamsters)
RO1HL-23153-01 Mechanisms of altered CA20 transport in
ischemic heart (dog, rabbit)
ROlHL-23161-01 0001 Biology of myocardial ischemia -
Mitochondrial lipid metabolism and cardiac ischemia (rat,
dog)
PURINE NUCLEOTIDES, ADENINE NUCLEOTIDES,
AMP
P50HL-17651-04 0041 Ischemic heart disease specialized
center of research - Biochemical indices of ischemic injury
(guinea pig)
ROlHL-23153-01 Mechanisms of altered CA20 transport in
ischemic heart (dog. rabbit)
PURINE NUCLEOTIDES, ADENINE NUCLEOTIDES,
AMP CYCLIC
ROlHL-05883-18 0002 Reflex control of resistance and
capacitance vessels - Adenosine, adenine nucleotides and
vascular smooth muscle (dog)
POlHL-0628518 0178 Cardiovascular-respiratory
physiology and biochemistry - Biochemical regulation of
hypertrophy (rats, rabbits)
** POlHL-06285-18 0186 Cardiovascular-respiratory
physiology and biochemistry ■ Leukocyte hormone receptors
and cyclic nucleotides (tissue culture)
POlHL-06285-18 0195 Cardiovascular-respiratory
physiology and biochemistry - Thyroid thermogenesis and
sodium transport (rats)
POlHL-06285-18 0200 Cardiovascular-respiratory
physiology and biochemistry - Medullary counter-current
system (animals)
POlHL-06296-18 0005 Cardiovascular and pulmonary
adaptation to stress - Regulation of ventricular
pertormance (animals)
POlHL-06314-17 0047 Immunologic mechanisms in
cardiovascular disease - Role of intravascular coagulation
(human, animals)
POlHL-06314-17 0055 Immunologic mechanisms in
cardiovascular disease - Genetics and cell biology
ROlHL-08508-15 Cardiac conductivity and automaticity
(human, dogs, rabbits)
POlHL-1034213 0011 The integrated function of
respiration and circulation ■ Control of respiration 1 -
Peripheral chemoreceptor studies (cats)
ROlHL-10384-13 Blood flow and nucleotide metabolism
(animals)
** POlHL-11414-11 0004 Thrombosis and atherosclerosis
program - Platelet function and nonthrombogenic surfaces
(human)
447
ROIHL 11880 10 Physiology and pathology of blood
platelets (human, dogs)
POIHI 12373 10 0002 Cardiopulmonary physiology and
pathophysiology Determinants ol pertormance of the
whole heart (dogs)
POIHL 12373 10 0012 Cardiopulmonary physiology and
pathophysiology Biochemistry of the sympathetic nervous
system (rats, rabbits, pigeons)
POIHL 12738 10 0076 Physiologic pharmacology and its
clinical applications Pediatric cardiac electrophysiology
and pharmacology (human, dogs)
POIHL 12738 10 0108 Physiologic pharmacology and its
clinical applications Developmental electrophysiology and
pharmacology (human, animals)
POIHL 12738 10 0134 Physiologic pharmacology and its
clinical applications Adenylate cyclase and cAMP
phosphodiesterase in cardiac development (dogs)
R01HL-12740-10 Hypocholosterolemic agents -
Stereochemistry (rats)
R01HL1330608 Pharmacological control of cardiac
membrane currents (cattle, rabbits)
R01HL1371508 Myocardial adenyl cyclase (rats)
POlHL-13737-07 0031 Assisted circulation Myocardial
ischemia- Biochemical changes (dogs)
ROlHL-13870-09 Control of myocardial sarcotubular
calcium stores (dogs)
ROlHL-13936-06 Microvascular responses in hypertension
(human, rats)
'* P50HL-14141-05 0002 SCOR for atherosclerosis in
childhood Intrauterine environment of proband group
(human)
P50HL-14147-08 0001 Specialized center of research in
thrombosis - Role of aspirin, other anti-platelet agents in
platelet function (rat, human)
P50HL-14153-07 0014 Johns Hopkins Lung Center-
Chronic diseases of airways - Mediator release in asthma
(human)
P50HL 14214-07 0015 Newborn lung center for hyaline
membrane disease - Hormone effect on cyclic nucleotide
lipid synthesis in developing lung (animal)
P50HL-142 17-08 0058 Specialized center of research in
thrombosis - Mechanisms of induction and inhibition of
platelet reaction (human, pig)
** POlHL-14388-07 0172 Regulation of the circulation in
pathological states - cAMP-dependent protein kinase from
heart and vascular smooth muscle (guinea pigs)
POlHL-14388-07 0191 Regulation of the circulation in
pathological states ■ Regulation of chloride transport in
epithelial membranes (turtles)
ROlHL-14523-07 Generation and regulation of force in
smooth muscle (animals)
ROlHL-14706-07 Fetal hearts in organ culture (mice)
ROlHL-147 13-06 Hypothermia and the heart (bats, guinea
pigs)
ROlHL-14720-08 Factors governing the renal excretion ot
acid (humans, rats)
ROlHL-15002-07 Biochemical pharmacology of guanylate
cyclase in lung (cattle, rats)
P50HL-15092-07 0005 Immune and fibrotic response to
occupational environments - Respiratory and immunologic
evaluation of toluene diisocyanate exposure (human)
ROlHL-15447-06 Vascular role of prostaglandin and cyclic
nucleotides (rats)
R01HL-15696-06 Mechanism and role of cyclic GMP in
heart (animals)
ROlHL-15728-06 The carbohydrate of the blood-clotting
glycoproteins (mammals)
** ROlHL-15764-05 CAMP dependent protein kinase in
cardiac contraction (dogs)
*• ROlHL-15930-06 Hormonal control of lipid and lipoprotein
synthesis (rats)
ROlHL-15985-06 Metabolic and hormonal control of
cardiac contraction
ROlHL-161 52-06 Electrophysiology of neonatal to adult
heart (cats, frogs, guinea pigs)
ROlHL-16233-05 Molecular cardiology of MDP-induced left
ventricular failure (dogs)
R01HL16240-05 The cardiac histamine receptor (rabbits,
guinea pigs)
ROlHL-16436-04 Role of calcium and thyroxine in heart
function (rats)
POlHL-16769-05 0002 Pathobiologic and host defense
reactions in the lung - Pathogenesis of complement
dependent injury to the lungs (rabbits)
ROIHL- 169 38-05 Effect ot physical forces on blood (dogs,
human)
P60HL-17269-04 0019 National heart and blood vessel
research and demonstration center - Sarcoplasmic
reticulum (dog. rabbit, hamster, cat!
P50HL-17646-04 0017 Study of ischemic heart disease -
Dysrhythmia associated with acute myocardial infarction
(human, cat)
P50HL-17682-04 0020 Study of ischemic heart disease -
Nucleotide and nucleoside metabolism in ischemic
myocardium
ROlHL-17729-04 Stimulus-response coupling in platelets
(human)
ROlHL-17907-04 Brain regulation of cardiac arrhythmia
(pigs, cats, rats)
ROlHL-18050-04 Mechanisms of cardiovascular
teratogenesis (chick embryo) k embryo)
PUR
ROIHI 18070 04 Regulation ot (ntrepulmoniry airwayt
and vessels (human, animals)
ROIHL 18148 04 Adrenal catecholamine secretion
ROIHI 181/6 02 Effect of thyroid hormone on cultured
cardiac cells (rats)
ROIHL 18260 04 Cyclic nucleotide metabolism in lung
tissue (cattle)
ROIHL 18272 03 Heart adenyl cyclase complex (beef
heart)
ROIHL 1828003 Regulation of cardiac contractility and
metabolism (rats)
P50HL 1831803 0015 Pathogenesis and complicationt of
hypertension Cultured smooth muscle cells and
microvessel metabolism (mammals)
ROIHL 18682 03 Protein kinase and cholesterol
metabolism in aorta (rabbits)
ROIHL 18795 04 Ischemic arrhythmias -Effect of
autonomic tone (dogs, rats, guinea pigs)
P01HL18827-02 0005 Platelet vessel w^ll interactions in
thrombogenesis Platelet vessel wall interactions in
thrombogenesis (human)
** R01HL18937 03 Cyclic nucleotides and calcium in
platelets (human)
•* ROIHL 19027-03 Calcium and cyclic AMP in causation of
hypertension (rats)
•* ROlHL-19057-03 Catecholamines and cyclic AMP in
cardiovascular system (rats, dogs)
ROlHL-1906203 Pharmacologic control of mast cell
phosphodiesterase (human, rats)
** ROlHL-191 15-02 Hormonal control of tracheobronchial
cyclic AMP (rats, guinea pigs)
ROlHL-19132-04 Role of zinc transferrin in lymphocyte
transformation (human)
P50HL-19156-02 0004 Pulmonary SCOR -Chronic diseases
of airways ■ Interactions between mast cells, mediators
and nerves in canine asthma
" ROlHL-19181-02 Regulation of heart cAMP-dependent
protein kinase (rodents)
P01HL19242-02 0003 Study of vascular smooth muscle -
Vasoactive metabolites from vascular muscle and
parenchymal tissue (animal)
** P01HL19242-02 0004 Study of vascular smooth muscle -
Cyclic nucleotide metabolism in smooth muscle cultures
(human, rats)
ROlHL-19325-03 Phosphodiesterase inhibition and muscle
contraction
ROlHL-19394-03 Biochemistry and regulation of taurine in
the heart (rats, guinea pigs, cats)
POlHL-19737-02 0002 Cellular and molecular aspects of
respiratory physiology - Airway smooth muscle in health
and disease (human, animals)
ROlHL-19752-03 Phospholipid synthesis by fetal lung in
organ culture (rats)
ROlHL-20114-02 Collagen-platelet interaction and human
aorta collagen (human)
** ROlHL-20 125-02 Cyclic nucleotides and alveolar
macrophage activation (rabbits)
ROlHL-20251-02 A novel approach to nonthrombogenic
polymer surfaces (sheep, cattle)
ROlHL-20300-02 Histone H5 and avian erythropoiesis
(chickens, rabbits)
ROlHL-2047603 Effects of diabetes on cardiac
performance (rat)
ROlHL-20643-02 Analysis of heart cell contraction (rats)
ROlHL-20782-01 Coronary flow regulation by adenosine
(rats, dogs)
ROlHL-20783-02 Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
P01HL-20948-02 0002 Molecular basis of cholesterol
metabolism LDL pathway in cell lines with informative
properties other than fibroblasts
ROlHL-20956-02 Early events following stimulation of
human platelets
** POlHL-20984-02 0006 Cellular mechanisms in cardiac
hypertrophy - Early biochemical aspects of cardiac
hypertrophy (rats)
ROlHL-2 1030-01 Calcium regulation and hypertension
(rats)
R23HL-21051-02 Adrenergic receptors and the adenylate
cyclase system (frog RBC)
ROlHL-2118701 Potassium, norepinephrine, and coronary
arterial tone (dogs)
R23HL-21320-02 Cyclic nucleotide metabolism in vascular
endothelium
ROlHL-21329-02 Beta-receptor regulation and cardiac
sites of drug action (cat. guinea pig. rat)
R23HL-2140902 Perinatal control of the ductus arteriosus
(sheep)
R23HL-21413-02 Structure and function of platelet
calcium-binding protein (human)
R23HL-21421-01 Myocardial and vascular contractility and
cyclic nucleotides (cattle, rats)
ROlHL-21654-01 Autonomic determinants of arrhythmia
due to Ischemia (cats)
ROlHL-21812-02 Actions of drugs and ions on cardiac
membranes (rabbits, guinea pigs)
ROlHL-2 1850-01 Calcium transport in the hypertrophied
myocardium (rats, animals)
ROlHL-21860-18 Factors influencing responses to
adrenergic drugs (guinea pigs, rats, cats)
** ROlHL-21995-01 Protein phosphorylation and adrenergic
effects
(contd)
•Excludes routine methodotogy OR covers only general prajeds which preclude indexing at the specific level.
••Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
PUR
ROlHL-22053-02 The disordered lipid metabolism of
diabetes mellitus (chickens, mammals, human)
ROlHL-2206402 Glycogen metabolism in anoxic diabetic
myocardium (rats)
ROlHL-22088-02 Metabolic basis for diabetic
microangiopathy (cattle)
ROlHL-2213501 Control of calcium fluxes across cardiac
membranes (dogs, rabbits, guinea pigs)
ROlHL-22136-02 Histamine and cardiac adenyl cyclase
ROlHL-22137-02 Structure-function pathology of isolated
heart cells (mice, rats)
ROlHL-22426-01 Initiation of the heartbeat-A voltage-
clamp study (bullfrogs, rabbits)
R23HL-22490-01 Neurotransmitter receptors of cultured
heart cells
ROlHL-22522-01 Cardioselectivity of beta-adrenoceptor
antagonists
ROlHL-22566-01 Mesoionic purinones as
phosphodiesterase inhibitors
POlHL-22619-01 0003 Cellular mechanisms of heart
failure - Digitalis induced inotropy in myocardial ischemia
heart failure (animals)
POlHL-22619-01 0009 Cellular mechanisms of heart
failure - Sarcoplasmic reticulum in cardiac, skeletal and
smooth muscle (rabbits, dogs)
POlHL-2261901 0010 Cellular mechanisms of heart
failure - Mitochondria in heart and smooth muscle (rabbits,
rats, dogs)
R23HL-22775-01 Muscarinic receptors in the developing
heart (chick embryo)
ROlHL-22812-01 Regulation of hepatic production of HDL
(rats)
ROlHL'22828-01 Adenosine and catecholamine interaction
in the heart (rats)
ROlHL-2283601 The spontaneously hypertensive kidney
(rats)
R23HL-22984-01 Cyclic AMP dependent protein kinases in
hypertension (rat)
ROlHL-23025-01 Adaptive heart growth in neonates and
adults (rats)
ROlHL-23245-01 Adrenergic receptors in pulmonary
vascular muscle (human, animal)
ROlHL-23587-01 Phosphorylation of myocardial protein
(guinea pigs)
R01HL-23990-01 Role of phosphoprotein in cardiac
inotropic responses
PURINE NUCLEOTIDES, ADENINE NUCLEOTIDES,
ADENOSINE PHOSPHATES
SEE ALSO FLAVIN NUCLEOTIDES, RIBOFLAVIN NUCLEOTIDES,
FAD
SEE ALSO PYRIDINE NUCLEOTIDES, NICOTINAMIDE RIBOTIDES.
NAD(H2)
ROlHL-13636-08 Effects of pharmacologic agents on heart
metabolism (human, rodents)
PURINE NUCLEOTIDES, ADENINE NUCLEOTIDES,
ATP
SEE ALSO BIOLOGICAL TRANSPORT, TRANSPORT ENERGETICS
SEE ALSO COENZYMES, COENZYME A
ROlHL-01974-24 Ion pump in the erythrocyte (rabbits,
guinea pigs)
** ROlHL-02363-20 Kinetics of water and electrolytes in
shock (dogs, rats)
POlHL-06285-18 0173 Cardiovascular-respiratory
physiology and biochemistry - Skeletal and cardiac muscle
function
POlHL-06285-18 0200 Cardiovascular-respiratory
physiology and biochemistry - Medullaiy counter-current
system (animals)
" POlHL-06312-17 0052 Surgical cardiology - Assay of
metabolic variables of rat heart
POlHL-06664-17 0040 Cardiopulmonary function in
remediable vascular disease - The coupling of ion transport
to metabolism (toads)
ROlHL-06950-17 Red cell metabolism (human,
vertebrates)
ROlHL-07449-17 Formation and survival of red blood cells
(human)
POlHL-0789615 0030 Environmental biomedical research
program - Narcosis caused by inert gases at raised
pressures (human, animals)
** ROlHL-09906-13 0018 Membrane transport processes in
red blood cells - Rapid photolytic release of ATP from a
protected analog-Na-K pump of RBC ghosts
R01HL1115412 Blood group antigens and antibodies
(human)
P01HL12157-11 0049 Functions and mechanisms of cell
membrane ion transport ■ Ouabain-insensitive cation
transport in duck red cells
P01HL12157-11 0054 Functions and mechanisms of cell
membrane ion transport - Simulation of electrogenic ion
transport in cardiac muscle
ROlHL-1325709 Inhalation anesthesia on myocardial
metabolism (dogs, swine, human)
POIHL- 13262-0 7 0022 Arterial wall in atherosclerosis -
Mechanisms of platelet prostaglanoin formation
ROlHL-13567'06 Ion transport across cell membranes
(human)
" P50HL1421708 0059 Specialized center of research in
thrombosis - Energy metabolism and platelet function
(human)
448
** ROlHL-14344-07 Platelet function and adenine nucleotide
metabolism (human)
POlHL-1438807 0173 Regulation of the circulation in
pathological states - Mechanisms of cardiac myosin ATPase
POlHL-14388-07 0194 Regulation of the circulation In
pathological states - Dopamine-beta-hydroxylase localization
and release in hypertension
ROlHL-14483-08 Energy conservation in heart
mitochondria (cattle, E coli, human)
P60HL-15157-07 0009 Comprehensive center for sickle
cell disease - Red cell membrane alterations during
sickling (human)
P60HL15157-07 0018 Comprehensive center for sickle
cell disease - Red blood cell membrane physiology in sickle
cell anemia (human)
ROlHL-15391-07 EPR studies on rotational motion of
myosin and actin
R01HL15692-07 Force and speed in skeletal and cardiac
muscle
R01HL-lS793-0e Molecular aspects of erythrocyte
membrane resealing (human)
P01HL-15835-06 0001 Study of muscles related to heart
disease - Control of contraction-relaxation of heart and
muscle (rabbits, chickens)
** P01HL15835-06 0011 Study of muscles related to heart
disease - Energetics and mechanism of muscle contraction
(frogs, rabbits)
P01HL15835-06 0012 Study of muscles related to heart
disease - Contraction and energetics of visceral and
vascular smooth muscles (rabbits)
P01HL-I5835-06 0013 Study of muscles related to heart
disease - Cardiac bioenergetics (rats)
ROlHL-160 10-16 Cellular basis of cardiac contractility
(frogs)
ROlHL-16355-05 Reactions of thrombin and collagen with
platelets (human)
ROlHL-16421-08 Determinants of RBC deformability and
capillary flow (human, mice)
ROlHL-16678-03 Fluorescent probe studies of heart
muscle proteins (rabbit, dog)
ROlHL-16931-04 Red cell storage and transfusion
(human, animals)
P50HL-17e51-04 0041 Ischemic heart disease specialized
center of research - Biochemical indices of ischemic injury
(guinea pig)
P50HL-17670-04 0023 Study of ischemic heart disease -
Energy metabolism in acute myocardial ischemic injury
(dogs)
P50HL-17682-04 0010 Study of ischemic heart disease -
Core clinical enzyme laboratory (human, mice, dogs, rats)
P50HL-1 7682-04 0018 Study of ischemic heart disease -
Biochemistry of ischemia -Heart cell and organ culture
(mice, rats, cattle)
" ROlHL-1808203 Erythrocyte phosphates and vertebrate
gas transport (amphibians, reptiles)
P01HL18208-04 0002 Center for the study of blood cell
rheology ■ Holography of RBC shape (human)
ROlHL-18601-01 Regulation of neurotransmitter release by
adenosine (rats)
POlHL-18708-03 0003 Oxygen, energy and contractility in
cardiac tissue - Structural-functional studies on cytochrome
c oxidase
P01HL18708-03 0004 Oxygen, energy and contractility in
cardiac tissue - Structural-functional studies on
sarcoplasmic reticulum (rabbits)
ROlHL-18798-04 0001 Nervous and ionic factors in
sudden cardiac death - Potassium loss during myocardial
ischemia (rabbits)
ROlHL-19299-03 Myoglobin and oxygen supply to heart
and muscle cells (rats, pigeons)
ROlHL-19378-03 Relation of mitochondrial changes to
cardiac failure (dogs, rats)
ROlHL-19488-03 Picosecond laser studies of heme-
proteins
R01HL19673-03 Surgical aspects of shock and hypoxia
(dogs, monkeys, rats)
ROlHL-19675-02 Coronary pharmacoangiography
POlHL-19737-02 0004 Cellular and molecular aspects of
respiratory physiology ■ Rapid reactions and erythrocyte
exchanges of blood during respiratory transport
ROlHL-20241-02 Shear and area moduli for abnormal red
cell membranes (human)
ROlHL-20262-02 Cardiac glycosides and the mechanism
of the sodium-potassium pump
ROlHL-202 78-02 Cellular mechanisms of renin secretion
(rats)
ROlHL-20484-03 Effects of diabetes on cardiac function
and metabolism (rats)
POIHL 2058101 0004 Vascular neuroeffector
mechanisms in health and disease - Neuroeffector
characteristics of mesenteric and pulmonary blood vessels
(rabbits)
POlHL-20592-02 0012 Cell biology of cardiac and
skeletal muscle - Contractile properties of skinned muscle
fibers (frogs)
ROlHL-20720-02 Myocardial protection during
cardiopulmonary bypass (dogs)
ROlHL-20783-02 Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
ROlHL-20902-02 Studies on marginal band system of
erythrocytes (amphibians, reptiles, fish)
PUR
ROlHL-20956-02 Early events following stimulation of
human platelets
POIHL 21016-02 0011 Sickle cell anemia and other
hemoglobinopathies - Metabolic effects of anti-sickling
agents (hamsters)
" R23HL-21128-02 ATP utilization in platelet contractile
mechanisms (human, rabbits)
R23KL-21213-01 A model for calcium homeostasis in
excitable tissue (marine worms)
R23HL-21488-01 Myosin-linked regulation in vertebrate
smooth muscle (calf aorta)
R23HL-21842-01 Control of sugar entry in normal and
diabetic heart (rats)
ROlHL-22194-02 Allosteric function of platelet contractile
proteins (human)
ROlHL-22290-01 Cardiac energy metabolism and protein
synthesis (mice)
ROlHL-22401-01 Regulation of tension and active state in
the heart
ROlHL'23138-01 Myocardial ischemia (dogs, rats, chick
embryo)
** ROlHL-23140-01 Determinants of irreversible ischemic
injury in heart (dog, rat)
ROlHL-23 153-01 Mechanisms of altered CA20 transport in
ischemic heart (dog, rabbit)
ROlHL-23240-01 Pulmonary vascular muscle metabolism
and contractility (rats, cattle)
ROlHL'23994-01 Biochemical properties of human cardiac
myosin
PURINE NUCLEOTIDES, ADENINE NUCLEOTIDES,
POLYADENYLIC ACID
ROlHL-04442-20 Mitochondrial assembly and replication
(fungi, wheat)
PURINE NUCLEOTIDES, GUANINE NUCLEOTIDES,
GMP
ROlHL-15985-06 Metabolic and hormonal control of
cardiac contraction
ROlHL-19148-03 Myocardial organelle lipid structure and
function (dog. rat)
R23HL-2 1409-02 Perinatal control of the ductus arteriosus
(sheep)
ROlHL-22088-02 Metabolic basis for diabetic
microangiopathy (cattle)
ROlHL-22426-01 Initiation of the heartbeat-A voltage-
clamp study (bullfrogs, rabbits)
PURINE NUCLEOTIDES, GUANINE NUCLEOTIDES,
GMP CYCLIC
POlHL-06308-18 0025 Mechanisms and therapy of
circulatory disease - Subcellular calcium pools in the
genesis of arrhythmias (dogs)
POlHL-06314-17 0047 Immunologic mechanisms in
cardiovascular disease - Role of intravascular coagulation
(human, animals)
POlHL-06314-17 0053
cardiovascular disease
Immunologic mechanisms in
Cellular functions controlled by
cyclic GMP (human, mice, guinea pigs)
POlHL-06314-17 0055 Immunologic mechanisms in
cardiovascular disease - Genetics and cell biology
ROlHL-11880-10 Physiology and pathology of blood
platelets (human, dogs)
POlHL-12738-10 0076 Physiologic pharmacology and its
clinical applications - Pediatric cardiac electrophysiology
and pharmacology (human, dogs)
ROlHL-13715-08 Myocardial adenyl cyclase (rats)
ROlHL-13936-06 Microvascular responses in hypertension
(human, rats)
P50HL-14214-07 0015 Newborn lung center for hyaline
membrane disease - Hormone effect on cyclic nucleotide
lipid synthesis in developing lung (animal)
ROlHL-14844-06 Mucous glycoprotein in human respiratory
epithelium (also wheat)
ROlHL-15002-07 Biochemical pharmacology of guanylate
cyclase in lung (cattle, rats)
P50HL-15092-07 0005 Immune and fibrotic response to
occupational environments - Respiratory and immunologic
evaluation of toluene diisocyanate exposure (human)
R01HL15447-06 Vascular role of prostaglandin and cyclic
nucleotides (rats)
ROlHL-15696-06 Mechanism and role of cyclic GMP in
heart (animals)
ROlHL-15985-06 Metabolic and hormonal control of
cardiac contraction
ROlHL-16436-04 Role of calcium and thyroxine in heart
function (rats)
POlHL-16769-05 0002 Pathobiologic and host defense
reactions in the lung ■ Pathogenesis of complement
dependent injury to the lungs (rabbits)
ROlHL-1693805 Effect of physical forces on blood (dogs,
human)
P50HL17646-04 0017 Study of ischemic heart disease -
Dysrhythmia associated with acute myocardial infarction
(human, cat)
P50HL-17682-04 0020 Study of ischemic heart disease -
Nucleotide and nucleoside metabolism in ischemic
myocardium
ROlHL-17907-04 Brain regulation of cardiac arrhythmia
(pigs, cats, rats)
R01HL18260-04
tissue (cattle)
Cyclic nucleotide metabolism in lung
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojects describing si
See Appendix for investigator's name
pecific research aspects.
and grant number.
PUR
ROIHI 1828003 Regulitlon o) cirdlic conttactility and
mttabolism (tats)
PSOHl 1831803 0015 Pathojenesis and complications ol
t)yp«rtension Culluced smooth muscle cells and
microvessel metabolism (mammals)
ROIHI 18795 04 Ischemic aiihythmias Ellect ol
autonomic tone (dogs. lats. guinea pigs)
ROIHL 1893? 03 Cyclic nucleotides and calcium in
platelets (human)
ROIHI 19062 03 Phaimacologic control ot mast cell
phosphodiesterase (human, rats)
P50HL1915602 0004 Pulmonary SCOR Chronic diseases
ol airways Interactions between mast cells, mediators
and nerves in canine asthma
POIHL 19242 02 0003 Study ot vascular smooth muscle
Vasoactive metabolites from vascular muscle and
parenchymal tissue (animal)
•• POIHL 19242 02 0004 Study ot vascular smooth muscle
Cyclic nucleotide metabolism in smooth muscle cultures
(human, rats)
ROIHL 19325-03 Phosphodiesterase inhibition and muscle
contraction
** ROlHL-20125-02 Cyclic nucleotides and alveolar
macrophage activation (rabbits)
ROIHL 2103001 Calcium regulation and hypertension
(rats)
R01HL21187-01 Potassium, norepinephrine, and coronary
arterial tone (dogs)
ROlHL-2119502 Innervation of the heart-Acetylcholine
receptors (trogs)
R23HL-21320-02 Cyclic nucleotide metabolism in vascular
endothelium
R23HL-2142101 Myocardial and vascular contractility and
cyclic nucleotides (cattle, rats)
ROlHL-2165401 Autonomic determinants of arrhythmia
due to ischemia (cats)
ROlHL-22064-02 Glycogen metabolism in anoxic diabetic
myocardium (rats)
R23HL-22075-01 Metabolism of arachidonic acid in blood
vessels (chickens, mammals)
R23HL-2249001 Neurotransmitter receptors of cultured
heart cells
ROlHL-2256601 Mesoionic purinones as
phosphodiesterase inhibitors
R23HL-22775-01 Muscarinic receptors in the developing
heart (chick embryo)
ROlHL-2283601 The spontaneously hypertensive kidney
(rats)
ROlHL-23025-01 Adaptive heart growth in neonates and
adults (rats)
R01HL-23245-01 Adrenergic receptors in pulmonary
vascular muscle (human, animal)
PURINE NUCLEOTIDES, GUANINE NUCLEOTIDES,
GUANOSINE PHOSPHATES
R01HL07449-17 Formation and survival of red blood cells
(human)
PURINE NUCLEOTIDES, GUANINE NUCLEOTIDES,
GTP
R01HL06950-17 Red cell metabolism (human,
vertebrates)
ROlHL-16931-04 Red cell storage and transfusion
(human, animals)
ROlHL-20544-02 Integrated regulation of myocardial
energy metabolism (rats, guinea pigs)
ROlHL-22290-01 Cardiac energy metabolism and protein
synthesis (mice)
PURINE NUCLEOTIDES, HYPOXANTHINE
NUCLEOTIDES, INOSINE MONOPHOSPHATE
P50HL-1421708 0059 Specialized center of research in
thrombosis ■ Energy metabolism and platelet function
(human)
** R01HL1898401 P50 effect on exercise limit in stable
angina (human)
PURINES
SEE ALSO PURINES PYRIMIOINES METABOLISM ERRORS
P01HL-2058I-01 0004 Vascular neuroeffector
mechanisms in health and disease - Neuroeffector
characteristics of mesenteric and pulmonary blood vessels
(rabbits)
PURINES, ADENINE
ROlHL-16931-04 Red cell storage and transfusion
(human, animals)
PURINES, GUANINE
POIHL-06312-17 0034 Surgical cardiology - Metabolic
factors in cardiac function -Creatine phosphate depletion
(animals)
PURINES, HYPOXANTHINE
P50HL-14217-08 0059 Specialized center of research in
thrombosis • Energy metabolism and platelet function
(human)
ROlHL-16412-04 Release of nucleosides from the ischemic
heart (human, dogs)
ROlHL-23140-01 Determinants of irreversible ischemic
injury in heart (dog, rat)
PURINES, OXYPURINES
SEE ALSO PURINES, HYPOXANTHINE
449
SEE Also PURINES. URIC ACID
SEE ALSO PURINES. XANIHINIS
*• ROIHL 22566 01 Mesoionic purinones as
phosphodiesterase inhibitors
PURINES, URIC ACID
SEE ALSO PURINfS PYRIMIOINES METABOLISM ERRORS.
GOUl
SEE ALSO PURINES PYRIMIOINES MEIABOIISM ERRORS.
HYPERURICEMIA
P50HL-14141 05 0008 SCOR lor atherosclerosis in
childhood Core laboratory
•• P60HL 15170 05 0019 Support for center lor sickle cell
anemia Renal handling of uric acid in sickle cell anemia
(human)
•* P60HL 16005 05 0019 Comprehensive sickle cell center
Handling ol uric acid in sickle cell anemia (human)
ROIHL 19984 02 Blood pressure and immunogenetic
factors in the young (human)
NOIHV 62955-04 Data collection in clinical pathology and
morbid anatomy (men)
PURINES, XANTHINES
P01HL16607 05 0003 Calcium ion and control of
cardiovascular lunction Calcium transport in
sarcoplasmic membranes (animals)
POIHL 1738205 0001 Chemical mediators ol acute
pulmonary disorders Chemical mediators and respiratory
mechanics in humans
ROlHL-18050-04 Mechanisms of cardiovascular
teratogenesis (chick embryo) k embryo)
P50HL 19153-02 0003 SCOR Pulmonary edemas -Eitology.
pathogenesis Possible inhibitors ol mediator release and
pulmonary vascular response (sheep)
** ROIHL 19325-03 Phosphodiesterase inhibition and muscle
contraction
ROlHL-2256601 Mesoionic purinones as
phosphodiesterase inhibitors
PURINES, XANTHINES, AMINOPHYILINE
R01HL10384-13 Blood flow and nucleotide metabolism
(animals)
R01HL12530-10 Emphysema -Respiratory function In
disease (human, dogs, rats)
ROlHL-14102-07 Human physiology at 5360 meters-
Mountain environment
POlHL-14985-07 0004 Adaptation to hypoxia - Control of
breathing in respiratory failure (human, dogs)
POlHL-14985-07 0009 Adaptation to hypoxia - Influence
of chemosensitivity on control of breathing during sleep
(human, dogs)
ROlHL-16760-05 Dynamic control of coronary blood flow
(dogs)
POlHL-1738205 0001 Chemical mediators of acute
pulmonary disorders - Chemical mediators and respiratory
mechanics in humans
ROlHL-17873-04 Pathophysiology of exercise-induced
asthma (human)
R01HL-19202-03 Adenosine, prostaglandins in relation to
coronary flow (guinea pigs)
POlHL-19242-02 0003 Study of vascular smooth muscle -
Vasoactive metabolites from vascular muscle and
parenchymal tissue (animal)
ROlHL-20989-01 Pathophysiology of bronchial asthma
(sheep, dogs)
R23HL-22895-01 Smoke inhalation -Biochemical and
cellular responses (rabbits, bacteria)
PURINES, XANTHINES, CAFFEINE
ROlHL-12774-08 Ionic coupling in activation of cardiac
muscle (frogs, guinea pigs)
POlHL-15835-06 0012 Study of muscles related to heart
disease - Contraction and energetics of visceral and
vascular smooth muscles (rabbits)
ROlHL-167 10-03 Myocardial subcellular localization of
calcium (dogs)
** ROlHL-17706-04 Psychosocial hypertension,
catecholamines and drugs (mice)
ROlHL-18050-04 Mechanisms of cardiovascular
teratogenesis (chick embryo) k embryo)
ROlHL-19325-03 Phosphodiesterase inhibition and muscle
contraction
R01HL-21145-02 Response of atria to hyperosmolality-
Mechanisms (rabbits)
R23HL-21320-02 Cyclic nucleotide metabolism in vascular
endothelium
R23HL-21325-02 Sarcomere kinematics in cardiac
contraction (rats, rabbits)
ROlHL-21670-01 Antiarrhythmic studies on 2-substituted
aminoindenes (dogs)
PURINES, XANTHINES, THEOPHYLLINE
SEE ALSO PURINES. XANTHINES, AMINOPHYLLINE
P50HL-141 53-07 0011 Johns Hopkins Lung Center-
Chronic diseases of airways - Allergy, airways reactivity
and asthma in human ragweed allergy
POlHL-14388-07 0191 Regulation of the circulation in
pathological states - Regulation of chloride transport in
epithelial membranes (turtles)
ROlHL-14844-06 Mucous glycoprotein in human respiratory
epithelium (also wheat)
ROlHL-20643-02 Analysis of heart cell contraction (rats)
ROlHL-2078302 Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
PYR
ROIHL 22065 01 Intractability, medication, and toping
slyle\ in a^thm^ (hiiin,iii)
PURINES-PVRIMIDINES METABOLISM ERRORS
P60HI 1/265 04 0008 Community blood rewurie center
support Research Blood genetic markers as biological
probes (human)
PURINES-PYRIMIDINES METABOLISM ERRORS.
GOUT
SEE ALSO PURINES PYRIMIOINES METABOLISM ERRORS,
HYPERURICEMIA
P60HL 16005 05 0019 Comprehensive sickle cell center
Handling of uric acid in sickle cell anemia (human)
ROIHL 1983909 Factors in youth predisposing to chronic
diseases dormer college students)
ROIHL 2101002 Glycemia, other traits and CV death in
40,000 persons
PURINES-PYRIMIDINES METABOLISM ERRORS,
GOUT DRUGS
SEE ALSO DISEASES, PATHOLOGIC PROCESSES.
INFLAMMATION. ANTIINFLAMMATORY AGENTS
ROIHL 00340 29 Electrolyte disturbance in cardio-renal
disease (human, dogs, rats)
PURINES-PYRIMIDINES METABOLISM ERRORS,
HYPERURICEMIA
SEE ALSO PURINES PYRIMIOINES METABOLISM ERRORS.
GOUT
P60HL 15170-05 0019 Support for center for sickle cell
anemia Renal handling of uric acid in sickle cell anemia
(human)
P60HL-1600505 0019 Comprehensive sickle cell center
Handling of uric acid in sickle cell anemia (human)
ROlHL-16774-04 Genetic epidemiology of hyperlipemia
(Honolulu)
ROlHL-21010-02 Glycemia. other traits and CV death in
40,000 persons
PURKINJE CELLS, CEREBELLAR
SEE BRAIN, CEREBELLAR CORTEX, PURKINJE CELLS
PURKINJE FIBERS
SEE HEART, CONDUCTION SYSTEM, PURKINJE FIBERS
PURPLE MEMBRANE, BACTERIAL
SEE PIGMENTS, BACTERIAL. BACTERIORHODOPSIN-RETINAL
PURPURA, FIBRINOLYTIC
SEE BLOOD COAGULATION DISORDERS, AFIBRINOGENEMIA
PURPURA HEMORRHAGICA
SEE BLOOD PLATELETS DISORDERS. THROMBOCYTOPENIC
PURPURA
PURSUIT TRACKING
SEE PSYCHOMOTOR FUNCTION. TRACKING TASK
PUTRESCINE
SEE AMINES, PUTRESCINE
PVC
SEE HEART DISORDERS, ARRHYTHMIA. PREMATURE
VENTRICULAR CONTRACTIONS
PYELONEPHRITIS
SEE KIDNEY DISORDERS. PYELONEPHRITIS
PYRAMIDAL TRACTS
SEE NERVOUS SYSTEM CENTRAL. PYRAMIDAL TRACTS
PYRANS
SEE OXINS, PYRANS
PYRAZINAMIDES, AMILORIDE
POlHL-06664-17 0039 Cardiopulmonary function in
remediable vascular disease - Transepithelial active
transport and cell volume regulation (frogs)
PYRAZOLIDINEDIONES, SULFINPYRAZONE
ROlHL-11775-11 Platelet mechanisms in disease (human,
primates)
R01HL-13754-08 Postoperative thromboembolism in
surgical patients (human)
P60HL-17265-04 0006 Community blood resource center
support - Research -Evaluation of platelet transfusions
(human, dog)
POlHL-18645-03 0006 Biology of the artery wall and
atherosclerosis - The platelet and atherosclerosis (monkeys,
baboons)
ROlHL-19112-03 Atherosclerosis studies (monkeys)
P01HL22163-01 0003 Surface thrombogenesis-
Mechanisms and prevention - In vivo mechanisms of
biomaterial thrombogenesis and its prevention (baboons)
PYRAZOLONES, PHENYLBUTAZONE
POlHL-11351-12 0015 Cellular and molecular
mechanisms of myocardial function - Effects of hypoxia
and ischemia on ion exchange and heart function (rabbits)
POlHL-18645-03 0006 Biology of the artery wall and
atherosclerosis - The platelet and atherosclerosis (monkeys,
baboons)
P01HL18827-02 0006 Platelet vessel wall interactions in
thrombogenesis - Platelet immune injury in man
ROlHL-22527-01 Prostacyclin-thromboxanes in the
cardiovascular system (human, rabbits)
(contd)
•Excludes routine methodology OR covers only general proiects which preclude indexing at the specific level.
••Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
PYR
450
QUI
ROlHL'22718-01 Cardiovascular drug interactions-
Metabolism models (dogs)
PYRAZOIOPYRIMIDINES
SEE DIAZOLODIAZINES. PYRAZOIOPYRIMIDINES
1 H-PYRAZOLO(3,4-D)PYRIMIDIN-4-OL
SEE DIAZOLODIAZINES, PYRAZOIOPYRIMIDINES. ALLOPURINOL
PYRENES
SEE CYCLICS. CARBOPOLYCYCLICS. PYRENES
PYRIDINAAAIDES, DISOPYRAMIDE
ROlHL-21221-02 Clinical antiarrhythmic and
pharmacodynamic studies
PYRIDINAMIDES, NICOTINAMIDE
R01HL-I9673-03 Surgical aspects of shock and hypoxia
(dogs, monkeys, rats)
PYRIDINAAAIDES, NICOTINAMIDE, N-METHYL-
ROlHL-02835-21 Renal transport carrier for organic
compounds (dogs, rats)
PYRIDINE CARBOXYLIC ACIDS, ISONICOTINIC
ACID
SEE ALSO AZO COMPOUNDS. HYDRAZINES, ISONIAZID
ROlHL-2298117 Membrane-associated functions in
microorganisms (bacteria, protozoa)
PYRIDINE CARBOXYLIC ACIDS, NICOTINIC ACID
ROlHL-03299-21 Dietary effects on cholesterol metabolism
(rats, rabbits)
R01HL0888812 Cooperative study of drugs and coronary
heart disease (men)
ROIHL-10445-09 Cooperative study of drugs and coronary
heart disease (men)
ROlHL-10705-09 Cooperative study of drugs and coronary
heart disease (men)
ROlHL-1 1372-08 Cooperative study of drugs and coronary
heart disease (men)
** ROlHL-11901-12 0006 Effects of metabolic surgery on
the hyperlipidemias - Drug therapy with ileal bypass
(rabbits)
P50HL-14197-07 0006 Support for center of research on
arteriosclerosis - Diets and drugs affecting lipid
metabolism (human)
P50HL-14236-05 0009 Prevention of premature
arteriosclerosis - Clinical studies on cholesterol metabolism
(human)
P50HL-14237-07 0006 Support for arteriosclerosis center
- Drug treatment of familial hyperbetalipoproteinemia
(human)
ROlHL-15374-03 Cooperative study of drugs and coronary
heart disease (human)
POlHL-18574-03 0006 Lipoprotein methodology and
biomedical applications - Lipoprotein transformation.
lipolytic enzymes, diet and lipid lowering agents
POlHL-20993-02 0004 Population dynamics of arterial
cells in atherogenesis Modifications of cholesterol balance
related to arterial cell divisions (swine)
PYRIDINE NUCLEOTIDES
ROlHL-19491-03 Mechanism of iron storage and
mobilization by ferritin (horse)
ROlHL-22315-01 Intraoperative cardiac oxygen supply-
demand (dogs, rabbits, rats)
PYRIDINE NUCLEOTIDES, NICOTINAMIDE
RIBOTIOES, NAD(H2)
SEE ALSO NAD LINKED ENZYMES
PaiHL-D6285-18 0178 Cardiovascular-respiratory
physiology and biochemistry - Biochemical regulation of
hypertrophy (rats, rabbits)
P01HL06285-18 0179 Cardiovascular-respiratory
physiology and biochemistry - Regulation of myocardial cell
grovrth (rats, chick embryo)
POlHL-07896-15 0032 Environmental biomedical research
program - Fluorometry study of brain exposed, to hyperbaric
oxygen (dogs, cats)
ROlHL-13028-09 Regulation of myocardial fatty acid
metabolism (rats)
ROlHL-13035-08 Heart mitochondrial malate
dehydrogenase regulation
ROlHL-13302-09 Uptake and metabolism of lipids by the
liver (rats)
ROlHL-14730-07 Fatty acid beta-oxidation in normal and
ischemic hearts (rabbits)
POlHL-17421-05 0007 Regulation and exchange in the
microcirculation - Core facilities -Fluorometric measurement
methods for microcirculation
ROlHL-19673-03 Surgical aspects of shock and hypoxia
(dogs, monkeys, rats)
ROlHL-201 16-01 Heart lactate dehydrogenase-The complex
with NADH (pig)
PYRIDINES
SEE ALSO ACRIDINES
SEE ALSO PESTICIDES, HERBICIDES, PARAQUAT
SEE ALSO QUINOLINES
SEE ALSO SULFANILAMIDES. SALICYLAZOSULFAPYRIDINE
ROlHL-12395-10 X-ray study of oxygen-carrying cobalt
complexes
ROlHL-20579-02 Synthesis of therapeutically important
alkaloids
PYRIDINES, AMINOPYRIDINES
ROlHL-22426-01 Initiation of the heartbeat -A voltage-
clamp study (bullfrogs, rabbits)
PYRIDINES, HYDROPYRIDINES
ROlHL-16003-08 Sources and roles of calcium in smooth
muscle excitation (rats)
PYRIDINES, METYRAPONE
** POlHL-06835-17 0059 Cardiovascular disease -
Metyrapone-induced hypertension in dog
ROlHL-17749-03 Adrenocortical factors in human
hypertension (human)
ROlHL-23969-01 Surfactant synthesis by type II cells in
vitro (rats)
PYRIDINES, NICOTINE
SEE ALSO CONSUMER PRODUCTS, TOBACCO AND TOBACCO
PRODUCTS
SEE ALSO PSYCHOLOGY, HABITS, SMOKING
ROlHL-08359-14 Morphopharmacology of vascular
adrenergic transmission (rabbits, rats)
ROlHL-09914-13 The myocardium in diabetes mellitus
(dogs, monkeys)
POlHL-14388-07 0155 Regulation of the circulation in
pathological states - Cardiopulmonary afferent activity,
carotid chemo-baroreceptor reflexes
P60HL-1 7269-04 0016 National heart and blood vessel
research and demonstration center - New analytical
methodology for atherosclerosis studies
P60HL-17269-04 0042 National heart and blood vessel
research and demonstration center - Social-psychological
smoking deterrents in schools
ROlHL-18467-03 Fingertip blood flow in normals and
Raynaud's disease (human)
ROlHL-18517-03 Intrinsic innervation of the heart (dogs)
P50HL-19362-02 0006 A/S SCOR-Atherosclerosis in
nonhuman primates - Effects of cigarette smoking on
atherosclerosis (baboon)
ROlHL-21 158-02 Cardiac receptors with vagal C-fiber
afferents (cats)
R23HL-22669-01 Cardiovascular effects from visceral
afferents (dogs)
PYRIDINOLS
POlHL-20993-02 0005 Population dynamics of arterial
cells in atherogenesis - Drugs other than hypolipidemic
drugs affecting atherosclerosis (swine, rabbits)
PYRIDOXAL ANALOGS
SEE VITAMIN B6, PYRIDOXAL ANALOGS
PYRIMIDINE NUCLEOSIDES, CYTOSINE
NUCLEOSIDES, CYTOSINE ARABINOSIDE
R01HL-20856-02 Platelet transfusions-Usage and
complications (human)
PYRIMIDINE NUCLEOSIDES, URACIL
NUCLEOSIDES, URIDINE
P01HL-063 14-17 0054 Immunologic mechanisms in
cardiovascular disease - Physiology of cell communications
(mice, frogs, guinea pigs)
PYRIMIDINE NUCLEOTIDES, URACIL
NUCLEOTIDES, URIDINE DIPHOSPHATE
** ROlHL-01813-25 Regulation of metabolism by drugs and
hormones (rats)
PYRIMIDINES, ALLOXAN
POlHL-08805-15 0025 Regulation of ventilation and
pulmonary circulation - Pulmonary edema (rabbits)
PYRIMIDINES, BARBITURATES
POlHL-06285-18 0147 Cardiovascular-respiratory
physiology and biochemistry - Metabolic regulation of
cerebral microcirculation (cats)
POlHL-08682-15 0037 Regulation of the cardiovascular
system - Central nervous regulation of cardiopulmonary
mechanisms (cats)
ROlHL-15659-05 Dynamic isolation studies of control of
respiration (human)
ROlHL-17091-05 Anesthetics and microvascular response
to hemorrhage (rats)
ROlHL-18590-03 Cerebral blood flow after cardiac arrest
(dogs, monkeys)
POlHL-18708-03 0010 Oxygen, energy and contractility in
cardiac tissue - Tissue oxygen utilization (rats, dogs)
R01HL2U76-02 Anticoagulant drug absorption
interactions (rats)
PYRIMIDINES, BARBITURATES, PENTOBARBITAL
POlHL-10436-13 0014 A multidisciplinary study of
congenital heart disease - Cardiovascular pharmacology
(dog)
P01HL-11678-1I 0059 Cardiovascular dynamics and their
control - Basic hemodynamics (dogs, rats)
ROlHL-154 16-06 Cardiovascular control in normal and
disease states (dogs, baboons)
ROlHL-19256-03 Arterial baroreceptors in cardiovascular
control (dogs)
PYRIMIDINES, BARBITURATES, PHENOBARBITAL
R01HL-14847-07 Mechanism of action of vitamin K and
anticoagulants (rats)
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
••Oriented significantly to atwve subject.
ROlHL-22718-01 Cardiovascular drug interactions-
Metabolism models (dogs)
PYRIMIDINES, BARBITURATES, THIOPENTAL
" POlHL-21584-02 0004 Respiratory mechanics in normal
and abnormal states - Effects of anesthesia on respiratory
mechanics (dogs)
PYRIMIDINES, MINOXIDIL
POlHL-06835-17 0037 Cardiovascular disease - Cardiac
hypertrophy in spontaneously hypertensive rat
P01HL-0e835-17 0053 Cardiovascular disease -
Vasodilating drugs (human)
POlHL-06835-17 0057 Cardiovascular disease - Studies
on cardiac hypertrophy
P50HL- 183 18-03 0019 Pathogenesis and complications of
hypertension - Renin-angiotensin system in blood pressure
regulation (human, rat, dog)
ROlHL-191 12-03 Atherosclerosis studies (monkeys)
ROlHL-22603-01 Trace metals, vascular activity and
hypertension (rats)
PYRIMIDINES, OROTIC ACID
ROIHL 23945-06 Pathologic effects on cells of modified
lipoproteins (rats, human)
PYROPHOSPHATE INFARCT IMAGING
SEE HEART VISUALIZATION*
PYROPHOSPHATES
SEE PHOSPHATES, PYROPHOSPHATES
PYRROLIDINEDIONES, MALEIMIDES
POlHL-16833-04 0001 Hemoglobin and red cell system in
hemoglobinopathies - Motility, association and ligand
binding in hemoglobin-Hydrogen exchange
POIHL- 16833-04 0003 Hemoglobin and red cell system in
hemoglobinopathies - Oxygen binding curves and equilibria
(human)
POIHL 16833-04 0009 Hemoglobin and red cell system in
hemoglobinopathies - Rheological studies of sickled cells
(human)
POlHL-16833-04 0015 Hemoglobin and red cell system in
hemoglobinopathies - Stereochemistry of hemoglobins from
magnetic circular dichroism (human)
POlHL-16833-04 0017 Hemoglobin and red cell system in
hemoglobinopathies - Sulfhydryl group blockade antisickling
effect (human)
POlHL-16851-04 0006 Human red cell membrane in
health and disease - Hexose transport and erythrocyte
membrane proteins (human)
PYRROLIDINES
SEE ALSO PYRIDINES, NICOTINE
POlHL-08214-15 0006 Chemical and biological properties
of lipids - Analysis and properties of lipids
PYRROLIZIDINE ALKALOIDS, SENECIO
SEE ALKALOIDS, SENECIO
PYRROLIZINE ALKALOIDS, MONOCROTALINE
SEE ALKALOIDS, MONOCROTALINE
PYRUVATE DEHYDROGENASE
SEE OXIDOREDUCTASES, PYRUVATE DEHYDROGENASE
PYRUVATE KINASE DEFICIENCY
SEE METABOLIC DISORDERS INBORN, PYRUVATE KINASE
DEFICIENCY
PYRUVATE OXIDASE
SEE OXIDOREDUCTASES, PYRUVATE OXIDASE
PYRUVATES
SEE FAHY ACIDS, PYRUVATES
QUADRUPLETS
SEE FAMILY, TWINS AND MULTIPLETS
QUAIL
SEE BIRDS, QUAIL*
QUALITY, DIAGNOSTIC
SEE DIAGNOSTIC QUALITY-STANDARDS
QUALITY OF DRUGS
SEE DRUG QUALITY-STANDARDS
QUALITY OF HEALTH CARE
SEE HEALTH CARE QUALITY
QUANTUM (CHEMISTRY)
SEE CHEMISTRY, QUANTUM (GENERAL)
QUATERNARY AMMONIUM COMPOUNDS
SEE AMMONIUM QUATERNARY
QUEBRACHINE
SEE ALKALOIDS, RAUWOLFIA TYPE, YOHIMBINE
QUESTIONNAIRES
SEE INFORMATION GATHERING (DATA COLLECTION),
QUESTIONNAIRES
QUINACRINE
SEE ACRIDINES. QUINACRINE
QUINIDINE
SEE QUINUCLIOINES. QUINIDINE
(contd)
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
QUI
QUINOUNE BLUE
SEE CYANINE
QUINOUNES
SEE ALSO QUINUCEIDINES. QUINIDINE
ROIHL 20S/9 02 Synthesis ol therapeutically important
alkaloids
QUINOUNES, BISBENZYLISOQUINOLINES
ROIHL 129/1 15 Reactions ol alholoids and their analogs
QUINOUNES, CHLOROQUINE
POIHL 06370 17 0004 Cardiopulmonary and renal
pathology research center Lymphocytes in gratt reiection
and immune surveillance (human)
POIHL 113S1 12 0015 Cellular and molecular
mechanisms ol myocardial tunction EHects ol hypoxia
and ischemia on ion exchange and heart function (rabbits)
POIHL 16833 04 0014 Hemoglobin and red cell system in
hemoglobinopathies Erythrocyte membrane damage in Hb
SS disease (human)
P50HL 1766904 0011 Ischemic heart disease center
(SCOR) Lysosomal tunction and lysosomal enzymes in
normal and ischemic heart (rabbit)
POIHL 18645 03 0006 Biology of the artery wall and
atherosclerosis The platelet and atherosclerosis (monkeys,
baboons)
POIHL 2094802 0002 Molecular basis of cholesterol
metabolism LDL pathway in cell lines with informative
properties other than fibroblasts
QUINOUNES, ISOQUINOUNES
SEE ALSO ALKALOIDS. BERBINES
R01HL1297115 Reactions of alkoloids and their analogs
ROlHL-2057902 Synthesis of therapeutically important
alkaloids
QUINOUNES, ISOQUINOUNES, PAPAVERINE
POlHL-14388-07 0157 Regulation of the circulation in
pathological states Autoregulation of renal blood flow and
distribution in sodium excretion control
ROlHL-19202-03 Adenosine, prostaglandins in relation to
coronary flow (guinea pigs)
ROlHL-19675-02 Coronary pharmacoangiography
ROlHL-21742-01 Frequency-dependent drug actions in
cardiac muscle (rabbits)
ROlHL-22354-01 Alphaadrenergic effects on heart
metabolism (rats)
R23HL-22975-01 Dynamics of autoregulation of muscle
blood flow (dogs)
R01HL2331201 Hemodynamics and vasoactivity in renal
hypertension (human, dogs)
QUINONE REDUCTASE
SEE OXIDOREDUCTASES, NAD(P)H DEHYDROGENASE
(QUIl^ONE)
QUINONES
SEE ALSO VITAMIN K
R01HL-20577-03 The mechanism of action of vitamin K
QUINTUPLETS
SEE FAMILY, T\NINS AND MULTIPLETS
QUINUCUDINES
POlHL-20984-02 0005 Cellular mechanisms in cardiac
hypertrophy ■ Neurohumoral receptors in cardiac growth
and compensatory hypertrophy (animals)
ROlHL-23013-01 Smooth muscle development in vitro
(chick embryo)
QUINUCUDINES, QUINIDINE
ROlHL-05806-18 Analysis ol antiarrhythmic agents (dogs,
rabbits)
POlHL-06308-18 0029 Mechanisms and therapy of
circulatory disease - Characterization of the patient with
recurrent ventricular arrhythmias
POlHL-0630818 0037 Mechanisms and therapy of
circulatory disease - Electrophysiology, blood flow, and ANS
in ventricular fibrillation (dogs)
R01HL07776-15 Sudden death and cardiac arrhythmias
(human, dogs, cats)
POlHL-12373-10 0013 Cardiopulmonary physiology and
pathophysiology - Effects of cardiovascular drugs on left
ventricular function (dogs)
P0IHL12738-10 0044 Physiologic pharmacology and its
clinical applications Cardioactive drugs and
electrophysiological properties of cardiac cells (sheep)
POlHL-12738-10 0136 Physiologic pharmacology and its
clinical applications -
P01HL13108-09 0008 Clinical heart transplantation ■
Physiology and pharmacology of the transplanted human
heart
POlHL-1310809 0017 Clinical heart transplantation ■
Electrophysiology of the transplanted denervated human
heart
POlHL-13108-09 0019 Clinical heart transplantation -
Effect of autonomic nervous system on arrhythmias
(human)
R01HL14899-07 Mechanism and prevention of cardiac
arrhythmias (dogs)
ROlHL-16076-06 Electrophysiology of fibrillation and
defibrillation (human)
ROlHL-16710-03 Myocardial subcellular localization of
calcium (dogs)
45 I
ROlHt W993 04 0003 Ventricular dynamics from
surgically inserted markers tllects ol pharmacologic
agents on lelt ventricular dynamics (human)
ROIHL 21221 02 Clinical antiarrhythmic and
pharmacodynamic studies
ROIHL 21672 01 Antiarrhythmic drug action on VMAZ ol
cardiac cells
ROIHL 21742 01 Frequency dependent drug actions in
cardiac muscle (rabbits)
ROIHL 22568 01 pH effect in heart cells Influence of
cardiac drugs (tissue culture, rats)
RABBITS
SEE MAMMALS, UGOMORPHS*
RACIAL FACTORS IN HYPERTENSION
SEE CARDIOVASCULAR DISORDERS, HYPERTENSION
(SYSTEMIC), GENETICS ASSOCIATED
RACIAL STOCKS
SEE SOCIAL GROUPS, RACIAL STOCKS
RADIATION, ELECTROMAGNETIC WAVES
SEE ALSO PHOTOBIOLOGY
SEE ALSO PHOTOCHEMISTRY
ROIHL 207 16 02 Freezing and electromagnetic thawing ol
platelets (rats)
RADIATION, ELECTROMAGNETIC WAVES,
MICROWAVE RADIATION
SEE ALSO TEMPERATURE, HEAT, MICROW/AVE HEATING
R01HL19848-02 Contractile activation by rapid
temperature jumps (frogs)
** ROlHL-20077-02 External cardiac stimulation with
microwave radiation (dogs)
** ROlHL-20110 02 Microwave methods of lung water
measurement (dogs, phantom models)
RADIATION, IONIZING RADIATION
ROlHL-21194-02 Development of antithrombogenic plastic
biomaterials
RADIATION, NEUTRON RADIATION
POlHL-1385116 Cyclotron produced isotopes in biology
and medicine (human, animals)
RADIATION, PARTICLE ACCELERATORS
** POIHL 1385116 Cyclotron produced isotopes in biology
and medicine (human, animals)
ROlHL-16553-05 Diagnosis of myocardial infarction by
radioisotopes (mice, rats, goats)
ROlHL-20677-02 Radionuclide studies in congenital heart
disease
RADIATION EFFECTS
SEE ALSO RADIATION SENSITIVITY
** P01HL07896-15 0046 Environmental biomedical research
program - Treatment of radiation induced tissue injury by
hyperbaric oxygen (human)
ROlHL-0869615 0012 Orthotopic heart transplantation ■
Transplantation immunology-Modulation of donor
antigenicity (dogs)
P50HL-14212-07 0006 Correlated studies of pulmonary
fibrosis ■ Alveolar macrophage physiology (human, rodents,
rabbits)
P50HL142 12-07 0014 Correlated studies of pulmonary
fibrosis - Pulmonary lavage cells, secretions in diffuse
intersititial lung disease (human)
ROlHL-14826-05 External isotope assay of atherosclerosis
(rats, rabbits)
P50HL-15061-07 0004 Response of lung to injury -
Biochemical abnormalities in connective tissues (rats)
ROlHL-15526-05 Respiratory mechanics in children
** R01HL-15740-06 In vitro studies on heart cell function
(rats)
ROlHL-161 19-05 Spleen and marrow allografts in
hereditary anemia (mice)
P01HL15387-04 0003 The blood vessel and
thrombogenesis - Blood vessel healing (rabbits)
ROlHL-19488-03 Picosecond laser studies of heme-
proteins
ROlHL-20895-03 0006 Cineangiographic studies of
cardiovascular system ■ Cardiomyopathy-Hemodynamic,
radiologic, morphologic abnormalities (dog, rabbit)
** ROlHL-21589-01 Radiographic contrast toxicity in
ischemic heart
NOlHV-32950-08 Blood compatible poly-electrolytes
RADIATION HAZARDS
SEE RADIOLOGICAL HEALTH, RADIATION HAZARDS
RADIATION IMMUNOSUPPRESSION
SEE IMMUNITY, IMMUNOSUPPRESSION, RADIATION
IMMUNOSUPPRESSION
RADIATION SENSITIVITY
" R01HL-22371-0I Vascular changes in lung exposed to
radiation
RADIATION STUDY SECTION
** ROlHL-09913-13 Cerebral veins -Anatomic and radiologic
correlation (human)
** ROlHL-12715-10 Dynamic cardiovascular measurement
using ultrasound
M ROlHL-14148-07 The regional circulations
•Excludes routine methodology OR covers only general projects which preclude
•'Oriented significantly to above subject
indexing at the specific level.
M Grant has subprojects describing s!
See Appendix for investigator's name
RAD
* ROIHL 14826 05 Citernd iiotop* Mtay ol tlhtrotclcrotit
(rats, rabbits)
* ROIHL 15781 06 Guided vstculir oblltctation ol CNS
vascular lesions (human)
• ROlHt 16260 04 Development o( clinical cine ultrasound
cardiography
• ROIHL 16484 04 Radiographic ventriculometry lor coronary
heart disease (human)
* ROIHL 16487 05 Computer controlled two dimeniional
echocardiography
• ROIHL 1655305 Diagnosis ol myocardial inlarclion by
radioisotopes (mice. rats, goats)
'• ROIHL 1675905 Ultrasonic measurement o( cardiac
geometry and flow
'• ROIHL 1683005 Non invasive determination ol aortic
blood velocities (human)
'* ROIHL 17739 04 Acute myocardial infarct scintigraphy
(human, dogs, rats)
'* ROIHL 1776903 New methods ol studying blood
coagulation kinetics
•* ROIHL 18873 02 Early radiologic diagnosis of cardiac
failure (monkey)
"* ROIHL 1901903 Accurate transcutaneous Doppler blood
flow monitoring
** ROIHL 19232 03 ECHO changes in wall motion with
myocardial ischemia
** ROIHL 19289 03 Assessment of infusion methods tor
myocardial mapping (dogs)
** ROlHL-19341-03 Ultrasonic detection ol the atherosclerotic
plaque
** R01HL19406-03 Grading ol atherosclerosis by CW doppler
ultrasound (human, dogs)
*• ROlHL-19537-03 Detection ol myocardial injury with
ultrasound (dogs)
** ROIHL 1967502 Coronary pharmacoangiography
** ROlHL-19791-02 Ultrasonic monitoring visceral blood
vessels
*• ROlHL-2027402 Gated imaging with the MGH x-ray
camera
" ROlHL-2067402 Evaluation of cardiac function with
radioactive tracers
** ROlHL-20677-02 Radionuclide studies in congenital heart
disease
** ROlHL-20751-02 Study of cerebral blood flow with stable
xenon and computerized tomography
** ROlHL-20869-01 Microvascular responses to ultrasound
** ROlHL-20872-02 Multidimensional echo imaging of the
ischemic heart
** ROlHL-20943-02 Comparision of microsphere and RBC
behavior in vivo
** ROlHL-21273-02 Fibrinogen labeling with radiometals
" ROlHL-21276-02 Development of 99-mTc myocardial
imaging agents
** R23HL-21279-02 Angiographic estimation of
atherosclerotic wall thickness
** ROlHL-2 1589-01 Radiographic contrast toxicity in
ischemic heart
** ROlHL-21985-01 Videoroentgenography in congenital heart
disease
** ROlHL-22178-01 Lung airway properties by acoustic
impulse reflection
** ROlHL-22371-01 Vascular changes in lung exposed to
radiation
** R01HL-22512-01 Ultrasonic instrumentation for
cardiovascular studies
** ROlHL-23983-01 Quantitative radiocardiography (human,
dogs)
RADIATION THERAPY
SEE ALSO NEOPLASTIC THERAPY. CANCER RADIOTHERAPY
SEE ALSO PHOTOTHERAPY
" POlHL-13108-09 0016 Clinical heart transplantation -
Total lymphoid irradiation for immune response (dogs)
RADIO
SEE ELECTRONIC STIMULATORS. RADIOFREQUENCY
CONTROLLED
RADIOASSAY, SCINTILLATION CAMERAS*
SEE ALSO RADIOGRAPHY. FLUOROSCOPY,
AUTOFLUOROSCOPY*
ROlHL-21707-01 Quantification of infarct size by emission
tomography (human, dogs)
RADIOASSAY, SCINTILLATION CAMERAS,
POSITRON*
** POlHL-13851-16 Cyclotron produced isotopes in biology
and medicine (human, animals)
P50HL-17665-04 0027 Study of ischemic heart disease
Positron imaging of regional myocardial perfusion (human,
dog)
RADIOASSAY, SCINTILLATION COUNTERS*
POlHL-06314-17 0052 Immunologic mechanisms in
cardiovascular disease ■ Role of cyclic nucleotides in
neutrophil function (human)
P50HL-14212-07 0013 Correlated studies of pulmonary
fibrosis - Mechanism of beryllium pathogenicity in the lung
(human, rabbit, guinea pig)
RADIOAUTOGRAPHY*
SEE ALSO HEART VISUALIZATION. RADIOCARDIOGRAPHY*
SEE ALSO RADIOASSAY. SCINTILLATION COUNTERS*
(contd)
ipecific research aspects,
and grant number.
RAD
SEE ALSO RADIODIAGNOSIS AND RADIOOIAGNOSTIC
METHODS. RADIOISOTOPE DIAGNOSIS
SEE ALSO RADIOGRAPHY, FLUOROSCOPY.
AUTOFLUOROSCOPY*
R01HL109I4-10 Renal sodium transport in experimental
aldosteronism (dogs)
ROlHL-15448-06 Surgical and metabolic aspects of
venous grafts, (dogs, mcnkeys. rabbits)
P50HL-191 55-02 0005 Pathophysiology of pulmonary
edema - Protein exchange sites and lymph protein
concentration in lung (mice, sheep)
P50HL-19171-02 0008 Pulmonary SCOR-Lung injury by
childhood infections - Host-parasite interaction-Electron
microscopy, radioautography, histochemistry
R01HL-19933-02 Membrane and red cell dysfunction in
hemolytic anemia (human)
R01HL-20895-03 0007 Cineangiographic studies of
cardiovascular system - Determinants of collateral
formation (dogs, hamsters)
POlHL-20994-02 9003 Dynamics of neutrophil elastase in
the lung - Autoradiography-Histology core
R01HL-22172-01 Hypotension, renal ischemia and effect of
mannitol (dogs, rats)
P01HL-226C2-01 9001 Pathophysiology of the
endothelium - Hflorphology core
RADIOAUTOGRAPHY, RADIOISOTOPE
TOMOGRAPHY*
SEE ALSO RADIOAUTOGRAPHY. RADIONUCLIDE SCANNING.
POSITRON AXIAL TOMOGRAPHY*
R01HL-21276-02 Development of 99-mTc myocardial
imaging agents
R01HL-21690-02 Sequential multinuclide study of acute
infarction (human, dogs)
** R01HL-21707-01 Quantification of infarct size by emission
tomography (human, dogs)
RADIOAUTOGRAPHY, RADIONUCLIDE
SCANNING*
SEE ALSO RADIOAUTOGRAPHY, RADIOISOTOPE TOMOGRAPHY*
P01HL-04664-18 0006 Cardiovascular and lung dynamics
- Cross section imaging of organ functions using emitted
radiation (dogs)
P50HL-14147-08 0007 Specialized center of research in
thrombosis - Radioactive tracers in recognition of
intravascular coagulation (human, dogs)
P50HL-14187-07 0008 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses - Pulmonary
thromboembolism (dogs, human)
P50HL-14217-08 0052 Specialized center of research in
thrombosis - Radioisotope nuclear medicine section
(human, dog)
P50HL-1 7648-04 0034 Study of ischemic heart disease -
Data management -Hemodynamic data
** P50HL-17655-04 0011 Study of ischemic heart disease -
Core facility-Cardiovascular nuclear medicine (human, dog)
P50HL-1 7665-04 0011 Study of ischemic heart disease -
Development of nev« methods for the determination of
infarct size (dog, human)
** P50HL-17669-04 0009 Ischemic heart disease center
(SCOR) - Infarct volume--99Tc stannous pyrophosphate
myocardial scintigrams (dogs, human)
** P50HL-1 7669-04 0023 Ischemic heart disease center
(SCOR) - Patients v»ith acute myocardial infarction and
myocardial ischemia (human)
P50HL-1 7670-04 0015 Study of ischemic heart disease -
Radionuclide studies of myocardial ischemia (human)
" P50HL-17670-04 0020 Study of ischemic heart disease -
Radionuclide evaluation of coronary artery disease (human,
dog)
P50HL-17682-04 0005 Study of ischemic heart disease -
Regional myocardial perfusion deficits and segmental
contraction disorders in man
P50HL-1 7682-04 0011 Study of ischemic heart disease •
Nuclear medicine core unit (human, dogs, rabbits, mice)
POlHL-18576-03 0013 Thrombosis research program
project - Early warning and monitoring test systems in
thrombotic disease (human)
*' ROlHL-2067402 Evaluation of cardiac function with
radioactive tracers
** ROlHL-20677-02 Radionuclide studies in congenital heart
disease
ROlHL-20761-02 Study of cerebral blood flow with stable
xenon and computerized tomography
ROlHL-20895-03 0003 Cineangiographic studies of
cardiovascular system - Densitometry in coronary stenosis
(human)
** P50HL 21006 02 0005 Specialized center of research in
arteriosclerosis - Regional myocardial perfusion in patient
with coronary artery disease (also dogs)
R01HL-2I273-02 Fibrinogen labeling with radiometals
ROlHL-21276-02 Development of 99-mTc myocardial
imaging agents
** ROlHL-21278-01 Abnormal cardiac wall motion viewed
ultrasonically (human, dogs, phantoms)
M ROlHL-21684-02 Radionuclide infarct sizing and therapy
evaluation
** ROlHL-21684-02 0001 Radionuclide infarct sizing and
therapy evaluation - Evaluating preservation of ischemic
myocardium by radioisotope methods (dog)
** ROlHL-21684-02 0002 Radionuclide infarct sizing and
therapy evaluation - Evaluating myocardial imaging agents
in global and regional ischemia (rabbits)
452
ROlHL-21684-02 0004 Radionuclide infarct sizing and
therapy evaluation - Image analysis-Kinetics of infarction,
ventricular function (human, animal)
ROlHL-21684-02 0005 Radionuclide infarct sizing and
therapy evaluation - Clinical evaluation of radioisotope
imaging methods for quantifying infarct size
ROlHL-21690-02 Sequential multinuclide study of acute
infarction (human, dogs)
ROlHL-21707-01 Quantification of infarct size by emission
tomography (human, dogs)
ROlHL-21751-02 Thallium and antimyosin in ischemia and
infarction
Thallium and antimyosin in
- In vitro models of ischemia and
Immunologic mechanisms in
Transplantation biology and
Thallium and antimyosin in
- Canine models of ischemia and
Thallium and antimyosin in
- Human studies -Ischemia and
** ROlHL-21751-02 0001
ischemia and infarction
infarction (rats, mice)
** ROlHL-21751-02 0002
ischemia and infarction
infarction
** ROlHL-21751-02 0003
ischemia and infarction
infarction
** ROlHL-21793-02 Functional infarct size by gated
radioangiography (human, dogs)
ROlHL-2285201 Diagnostic techniques in venous
thromboembolism (human)
ROlHL-23983-01 Quantitative radiocardiography (human,
dogs)
RADIOAUTOGRAPHY, RADIONUCLIDE
SCANNING, POSITRON*
** P50HL-1 7665-04 0027 Study of ischemic heart disease -
Positron imaging of regional myocardial perfusion (human,
dog)
** ROlHL-19289-03 Assessment of infusion methods for
myocardial mapping (dogs)
RADIOAUTOGRAPHY, RADIONUCLIDE
SCANNING, POSITRON AXIAL
TOMOGRAPHY*
P50HL-14147-08 0007 Specialized center of research in
thrombosis - Radioactive tracers in recognition of
intravascular coagulation (human, dogs)
P50HL-17646-04 0002 Study of ischemic heart disease -
Core data management
** P50HL-17646-04 0009 Study of ischemic heart disease -
Regional metabolic derangements indicating ischemia
(rabbit, dog, human)
P50HL-1 7648-04 0004 Study of ischemic heart disease ■
Radionuclide imaging studies (human, pig)
P50HL-17665-04 0027 Study of ischemic heart disease -
Positron imaging of regional myocardial perfusion (human,
dog)
'* ROlHL-21697-01 Myocardium infarct sizing by 82Rb
emission tomography (dogs, human)
ROlHL-21751-02 0002 Thallium and antimyosin in
ischemia and infarction - Canine models of ischemia and
infarction
RADIOCARDIOGRAPHY
SEE HEART VISUALIZATION, RADIOCARDIOGRAPHY*
RADIODIAGNOSIS AND RADIODIAGNOSTIC
METHODS
SEE ALSO NEOPUSMS DIAGNOSIS, RADIODIAGNOSIS
R01HL099 13-13 Cerebral veins-Anatomic and radiologic
correlation (human)
Mechanical circulatory support -
POlHL-13330-08 0062
CORE facilities
P50HL-141 36-07 0005
obstructive diseases
Pulmonary SCOR-Airways
Radiographic studies of airways
obstructive disease (human)
P50HL-14187-07 0008 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses - Pulmonary
thromboembolism (dogs, human)
** P50HL-14 192-08 0008 Specialized center of research in
hypertension - New radiographic methods-Recognition of
renovascular hypertension (human, dog)
** ROlHL-16484-04 Radiographic ventriculometry for coronary
heart disease (human)
ROlHL-17769-03 New methods of studying blood
coagulation kinetics
ROlHL-18492-03 Measurement of regional coronary flow
reserve (human, dogs)
ROlHL-19289-03 Assessment of infusion methods for
myocardial mapping (dogs)
** ROlHL-201 10-02 Microwave methods of lung water
measurement (dogs, phantom models)
ROlHL-20274-02 Gated imaging with the MGH x-ray
camera
ROlHL-21719-01 Computed cardiac tomography in infarct
sizing (dogs, human)
RADIODIAGNOSIS AND RADIODIAGNOSTIC
METHODS, RADIOISOTOPE DIAGNOSIS
SEE ALSO NEOPLASMS DIAGNOSIS, RADIOISOTOPE DIAGNOSIS
P0IHL04664-18 0003 Cardiovascular and lung dynamics
X-ray projection image videometry (human, dogs)
POlHL-04664-18 0006 Cardiovascular and lung dynamics
Cross section imaging of organ functions using emitted
radiation (dogs)
POlHL-04664-18 0009 Cardiovascular and lung dynamics
- Biological signal and image processing techniques (dogs)
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
*'Onented significantly to above subject.
RAD
POlHL-06314-17 0065
cardiovascular disease
clinical transplantation
ROlHL'09315-15 Coronary insufficiency and myocardial
revascularization (human, dogs)
ROlHL-09914-13 The myocardium in diabetes mellitus
(dogs, monkeys)
ROlHL-10009-13 Regional lung function in man
POlHL-1 1310-12 0081 Mechanisms of cardiovascular
disease - Analysis of regional left ventricular function
(human)
ROlHL-12085-10 Lipoprotein-carbohydrate metabolism
(human, rats)
ROlHL-12322-10 Extrinsic factors influencing myocardial
performance (dogs, swine)
POlHL-12373-10 0002 Cardiopulmonary physiology and
pathophysiology - Determinants of performance of the
whole heart (dogs)
ROlHL-12833-09 Genetic and environmental influences on
lung disease (human)
ROlHL-1303608 Coronary thrombosis -Effects on
myocardium and in vivo detection (dogs, monkeys)
ROIHL 13654-08 Antilipemic regimes in peripheral
arteriosclerosis (human)
ROlHL-13824-06 Defense mechanisms in pathogenesis of
emphysema (human, dogs)
POlHL-13851-16 Cyclotron produced isotopes in biology
and medicine (human, animals)
P50HL-14147-08 0007 Specialized center of research in
thrombosis - Radioactive tracers in recognition of
intravascular coagulation (human, dogs)
P50HL-1414708 0016 Specialized center of research in
thrombosis - Nuclear medicine core laboratory (human,
dogs, rats, rabbits)
P50HL14214-07 0036 Newborn lung center for hyaline
membrane disease - Core-Biomedical engineering
P50HL-14217-08 0052 Specialized center of research in
thrombosis Radioisotope nuclear medicine section
(human, dog)
ROlHL-14826-05 External isotope assay of atherosclerosis
(rats, rabbits)
POlHL-15194-07 0017 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation and
effects of arteriographic lesions on flow (human)
ROlHL-16553 05 Diagnosis of myocardial infarction by
radioisotopes (mice. rats, goats)
P50HL-1 7646-04 0009 Study of ischemic heart disease -
Regional metabolic derangements indicating ischemia
(rabbit, dog, human)
P50HL-17648-04 0004 Study of ischemic heart disease ■
Radionuclide imaging studies (human, pig)
P50HL-17665-04 0011 Study of ischemic heart disease -
Development of new methods for the determination of
infarct size (dog. human)
P50HL17665-04 0027 Study of ischemic heart disease -
Positron imaging of regional myocardial perfusion (human.
dog)
P50HL-17667-04 0030 Study of ischemic heart disease -
Computerized clinical data acquisition and processing
P50HL-1 7670-04 0015 Study of ischemic heart disease ■
Radionuclide studies of myocardial ischemia (human)
P50HL17670-04 0020 Study of ischemic heart disease ■
Radionuclide evaluation of coronary artery disease (human.
dog)
P50HL17682-04 0005 Study of ischemic heart disease •
Regional myocardial perfusion deficits and segmental
contraction disorders in man
P50HL1 7682-04 0011 Study of ischemic heart disease ■
Nuclear medicine core unit (human, dogs, rabbits, mice)
ROlHL-17739-04 Acute myocardial infarct scintigraphy
(human, dogs, rats)
R01HL18467-03 Fingertip blood flow in normals and
Raynaud's disease (human)
POlHL-18576-03 0013 Thrombosis research program
project - Early warning and monitoring test systems in
thrombotic disease (human)
ROlHL-18606-04 Pathogenesis and measurement of
pulmonaiy edema (human, rabbits, dogs)
POlHL-18646-03 0008 Studies basic to heart
transplantation • Immunophysiology and early detection of
rejection (dogs)
ROlHL-18744-03 Preparation of radiopharmaceuticals from
drug analogs
R01HL-18805-04 0005 Sudden cardiac death and the
onset of myocardial infarction - Sudden death survivors-
Radionuclide studies (human)
ROlHL-19030-03 Tissue protection during circulatory
interruption (dogs)
ROlHL-19127-03 Synthesis of molecules for myocardial
imaging (rats)
ROlHL-19232-03 ECHO changes in wall motion with
myocardial ischemia
ROlHL-19370-03 Coronary capillary exchange -The effects
of ischemia (dogs, sheep)
ROlHL-19451-03 0001 Functional characteristics of the
left heart - Ventricular performance using epicardial
radiopaque markers (human)
R01HL19451-03 0003 Functional characteristics of the
left heart - Left ventricular segmental contraction (human,
dogs)
ROlHL-19451-03 0004 Functmnal characteristics of the
left heart - Quantitative coronary arteriography (human)
(contd)
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
RAD
POIHL 19717 02 0021 Response ol the lung to iniuiy
Gallium lunj sons in libiosing alveolitis (hamsleis)
•* POIHI 19717 02 0039 Response ot the lung lo injury
Lung scanning in alveolitis and asbestolic interstitial
pneumonia (human, animal)
•* ROIHL 2028302 Maintenance of cellular integrity in
ischemic hearts (cats)
•* ROIHL 2067702 Radionuclide studies in congenital heart
disease
ROIHL 20895 03 0001 Cineangiogiaphic studies ot
cardiovascular system Videodensitometry and valvular
regurgitation (human, dogs)
ROIHL 2089b 03 0002 Cineangiogtaphic studies ol
cardiovascular system Coronary disease Regional
myocaidial blood How (human, dog)
P50HL 21006 02 000b Specialized center of research in
arleiioscleiosis Regional myocardial perfusion in patient
with coionaiy artery disease (also dogs)
ROlHL-2 127302 Fibrinogen labeling with ladiometals
ROIHL 21276 02 Development ot 99 mTc myocardial
imaging agents
** R01HL21518-01 Improvement in regional ventilation-
perlusion resolution (human)
R01HL21572-01 Natural history of the postphlebitic
syndrome
M ROlHL-2 1684-02 Radionuclide infarct sizing and therapy
evaluation
** ROlHL-2 1684-02 0001 Radionuclide infarct sizing and
therapy evaluation ■ Evaluating preservation of ischemic
myocardium by radioisotope methods (dog)
** ROlHL-21684-02 0002 Radionuclide infarct sizing and
therapy evaluation ■ Evaluating myocardial imaging agents
in global and regional ischemia (rabbits)
** ROlHL-2168402 0004 Radionuclide infarct sizing and
therapy evaluation ■ Image analysis -Kinetics of infarction,
ventricular function (human, animal)
** ROlHL-2 168402 0005 Radionuclide infarct sizing and
therapy evaluation - Clinical evaluation of radioisotope
imaging methods for quantifying infarct size
** ROlHL-21690-02 Sequential multinuclide study of acute
infarction (human, dogs)
ROlHL-21751-02 0001 Thallium and antimyosin in
ischemia and infarction - In vitro models of ischemia and
infarction (rats, mice)
ROlHL-21751-02 0002 Thallium and antimyosin in
ischemia and infarction ■ Canine models of ischemia and
infarction
ROlHL-21751-02 0003 Thallium and antimyosin in
ischemia and infarction - Human studies-Ischemia and
infarction
" ROlHL-21793-02 Functional infarct size by gated
radioangiography (human, dogs)
** R23HL-22004-01 Imaging and ECG studies in acute and
chronic IHD (human)
** ROlHL-22567-01 Validation of a cholesterol absorption
method in man
ROlHL-22750-01 Digoxin in heart failure with sinus
rhythm (human)
ROlHL-23653-01 Protection of the ischemic myocardium
(dogs)
** ROlHL-23983-01 Quantitative radiocardiography (human,
dogs)
N01HV-62960-00 Techniques to protect ischemic
myocardium and minimize infant size (human)
RADIODIAGNOSTIC METHODS
SEE RAOIODIAGNOSIS AND RADIODIAGNOSTIC METHODS
RADIOFLUORESCENT PROBES
ROlHL-1773904 Acute myocardial infarct scintigraphy
(human, dogs, rats)
RADIOFREQUENCY CONTROLLED ELECTRONIC
STIMULATORS
SEE ELECTRONIC STIMUUTORS, RADIOFREQUENCY
CONTROLLED
RADIOGRAPHY*
SEE ALSO CARDIOVASCULAR VISUALIZATION, ROENTGEN
VIDEODENSITOMETRY*
SEE ALSO CEREBROVASCUUR VISUALIZATION.
CEREBROANGIOGRAPHY*
SEE ALSO GASTROINTESTINAL VISUALIZATION*
SEE ALSO HEART VISUALIZATION. ANGIOCARDIOGRAPHY*
SEE ALSO NEOPLASMS DIAGNOSIS. BREAST NEOPLASMS
DIAGNOSIS. MAMMOGRAPHY*
SEE ALSO PHYSICAL PROPERTIES. SOUND,
ULTRASONOGRAPHY
SEE ALSO RADIOAUTOGRAPHY*
SEE ALSO RESPIRATORY VISUALIZATION, BRONCHOGRAPHY*
** P50HL-14136-07 0005 Pulmonary SCOR-Airways
obstructive diseases - Radiographic studies of airways
obstructive disease (human)
** P50HL-14136-07 9004 Pulmonary SCOR-Airways
obstructive diseases - Radiology core (human)
P50HL-14136-07 9007 Pulmonary SCOR-Airways
obstructive diseases - Special facilities core
" P50HL-15092-O7 0013 Immune and fibrotic response to
occupational environments ■ Epidemiology core resource
P50HL-17670-04 0016 Study of ischemic heart disease ■
Core pathology laboratory (human, dogs, monkeys)
** ROlHL-21846-01 Cardiac failure detection by radiography
and optics (monkeys)
453
RADIOGRAPHY, CINEFLUOROGRAPHY*
ROIHL 19003 03 High precision densitometry of coronaiy
angiogiams
ROIHI 20895 03 0004 Cineangiogiaphic studios-of
cardiovascular system Cineangiography Coronary lesions
and ventiiculai function (human)
RADIOGRAPHY, CONTRAST MEDIA*
POIHL 04664 18 0001 Cardiovascular and lung dynamics
X ray projection image videodensitometry (dogs)
P50HL 1915602 0003 Pulmonary SCOR Chronic diseases
of airways Powdered tantalum to study airway morphology
and mucociliary clearance (human)
•* ROIHL 1967502 Coronaiy pharmacoangiography
** ROIHL 2127602 Development of 99 mTc myocardial
imaging agents
•* ROIHL 21589 01 Radiographic contrast toxicity in
ischemic heart
ROIHL 21719-01 Computed cardiac tomography in infarct
sizing (dogs, human)
** NOIHV 72930-02 Atherosclerosis assessment Angiography
and ultrasound (dogs, human)
NOlHV-7293102 Noninvasive detection of atherosclerotic
lesions (human, dogs)
RADIOGRAPHY, FLUOROSCOPY*
R01HL2284401 Phrenic nerve pacing-Noninvasive
diaphragm analysis (human, dogs)
RADIOGRAPHY, FLUOROSCOPY,
AUTOFIU OROSCOPY*
SEE ALSO RADIOASSAY. SCINTILLATION CAMERAS*
ROlHL-1414807 0009 The regional circulations -
Myocardial circulation in hypertension and atherosclerosis
(human)
RADIOGRAPHY, MICRORADIOGRAPHY*
SEE ALSO CARDIOVASCULAR VISUALIZATION.
MICROANGIOGRAPHY*
** P01HL04664-18 0008 Cardiovascular and lung dynamics
- Micrographic video imaging technique
P50HL-14136-07 0005 Pulmonary SCOR-Airways
obstructive diseases - Radiographic studies of airways
obstructive disease (human)
RADIOGRAPHY, PNEUMORADIOGRAPHY*
** POlHL-0637017 0017 Cardiopulmonary and renal
pathology research center - Detection of pulmonary lesions-
Radiologic pathologic correlation
POIHL- 178 13-04 0001 Lung disease and the oxygenation
of blood and tissue - Diffuse interstitial lung disease-
Pathophysiology (human, dogs)
RADIOGRAPHY, SCANNING (GENERAL)*
SEE ALSO BRAIN VISUALIZATION, BRAIN SCANNING*
SEE ALSO HEART VISUALIZATION, HEART SCANNING*
SEE ALSO PHYSICAL PROPERTIES. SOUND. ULTRASONIC
SCANNING*
SEE ALSO RADIOAUTOGRAPHY. RADIONUCLIDE SCANNING*
SEE ALSO RADIOAUTOGRAPHY. RADIONUCLIDE SCANNING,
POSITRON*
SEE ALSO RESPIRATORY VISUALIZATION, LUNG SCANNING*
SEE ALSO SKELETAL VISUALIZATION, BONE SCANNING*
POlHL-07293-17 0055 Non-invasive cardiovascular
measurements - Peripheral vascular transducer position
locating system
** POlHL-07293-17 0056 Non-invasive cardiovascular
measurements - Peripheral vascular system software
** POlHL-07293-17 0057 Non-invasive cardiovascular
measurements - Peripheral vascular scanner engineering
evaluation and error analysis (human)
** POlHL-07293-17 0058 Noninvasive cardiovascular
measurements - Peripheral duplex scanner physiologic
evaluation
RADIOGRAPHY, SCANNING, CAT*
SEE ALSO RADIOAUTOGRAPHY, RADIONUCLIDE SCANNING,
POSITRON AXIAL TOMOGRAPHY*
** POlHL-04664-18 0002 Cardiovascular and lung dynamics
■ X-ray cross section imaging of organs (dogs)
POlHL-04664-18 0003 Cardiovascular and lung dynamics
- X-ray projection image videometiy (human, dogs)
** POlHL-04664-18 0004 Cardiovascular and lung dynamics
- X-ray cross section imaging of the circulation (dogs)
** POlHL-04664-18 0006 Cardiovascular and lung dynamics
- Cross section imaging ol organ functions using emitted
radiation (dogs)
** POlHL-04664-18 0007 Cardiovascular and lung dynamics
. Development and application of ultrasound imaging
techniques
POlHL-04664-18 0009 Cardiovascular and lung dynamics
- Biological signal and image processing techniques (dogs)
POlHL-04664-18 0016 Cardiovascular and lung dynamics
- Computerized roentgenographic determination of total
lung capacity
** POlHL-13851-16 Cyclotron produced isotopes in biology
and medicine (human, animals)
POlHL-14388-07 0185 Regulation of the circulation in
pathological states - Reflex control of venous tone (human,
rabbits, dogs)
** R01HL16487-05 Computer controlled two dimensional
echocardiography
ROlHL-18873-02 Early radiologic diagnosis of cardiac
failure (monkey)
RAO
*• ROIHL 18968 03 Computei technotogy for tf«n»««<«l
tomography
ROIHI 19003 03 High preciMon deniitomeliy of coronary
angiograms
ROIHL 19289 03 Assessment of infusion methods tor
myocardial mapping (dogs)
ROIHL 202/4 02 Gated imaging with the MGH « lay
camera
•* ROIHL 20761 02 Study of cerebral blood (low with stable
xenon and computerized tomography
*• R23HI 21253 01 Anatomical models in computer aided
image analysis
*• R01HL2171901 Computed cardiac tomography in infarct
sizing (dogs, human)
RADIOGRAPHY, SCANNING, DSR
POIHL 04664 18 Cardiovascular and lung dynamics
POIHL 04664 18 0001 Cardiovascular and lung dynamics
X ray projection image videodensitometry (dogs)
POIHL 04664 18 0002 Cardiovascular and lung dynamics
X ray cross section imaging of organs (dogs)
P01HL04664 18 0003 Cardiovascular and lung dynamics
X ray projection image videometry (human, dogs)
POlHL-04664 18 0004 Cardiovascular and lung dynamics
- X-ray cross section imaging of the circulation (dogs)
P01HL04664 18 0006 Cardiovascular and lung dynamics
Cross section imaging of organ functions using emitted
radiation (dogs)
POIHL 04664 18 0007 Cardiovascular and lung dynamics
■ Development and application of ultrasound imaging
techniques
POIHL 04664 18 0008 Cardiovascular and lung dynamics
- Micrographic video imaging technique
POlHL-04664-18 0009 Cardiovascular and lung dynamics
- Biological signal and image processing techniques (dogs)
POlHL-04664-18 0010 Cardiovascular and lung dynamics
- Left ventricular dynamics (human)
POlHL-0466418 0011 Cardiovascular and lung dynamics
• Detection of abnormal segments of the human ventricle
by measure of asynergy
POlHL-04664-18 0016 Cardiovascular and lung dynamics
- Computerized roentgenographic determination of total
lung capacity
RADIOGRAPHY, TOMOGRAPHY*
SEE ALSO CARDIOVASCULAR VISUALIZATION.
ANGIOTOMOGRAPHY*
SEE ALSO RADIOAUTOGRAPHY. RADIOISOTOPE TOMOGRAPHY*
SEE ALSO RADIOGRAPHY. SCANNING. CAT*
ROlHL-09913-13 Cerebral veins -Anatomic and radiologic
correlation (human)
ROlHL-20761-02 Study ol cerebral blood How with stable
xenon and computerized tomography
RADIOGRAPHY, XEROGRAPHY
ROIHL- 1934 1-03 Ultrasonic detection of the atherosclerotic
plaque
RADIOIMMUNOASSAY
SEE IMMUNOLOGICAL TESTS AND IMMUNOASSAY,
RADIOIMMUNOASSAY*
RADIOISOTOPE DIAGNOSIS
SEE RAOIODIAGNOSIS AND RADIODIAGNOSTIC METHODS,
RADIOISOTOPE DIAGNOSIS
RADIOISOTOPE DIAGNOSIS OF NEOPLASMS
SEE NEOPLASMS DIAGNOSIS, RADIOISOTOPE DIAGNOSIS
RADIOISOTOPE (NUCLEAR) MEDICINE
(GENERAL)
SEE ALSO NEOPLASMS DIAGNOSIS, RADIOISOTOPE DIAGNOSIS
SEE ALSO RADIODIAGNOSIS AND RADIODIAGNOSTIC
METHODS, RADIOISOTOPE DIAGNOSIS
SEE ALSO RADIOPHARMACOLOGY
P50HL-14217-08 0052 Specialized center of research in
thrombosis - Radioisotope nuclear medicine section
(human, dog)
ROlHL-16553-05 Diagnosis of myocardial infarction by
radioisotopes (mice, rats, goats)
ROlHL-16791-03 Computer linkage for a dual camera
system
** P50HL-17648-04 0004 Study of ischemic heart disease -
Radionuclide imaging studies (human, pig)
** P50HL- 17655-04 0011 Study of ischemic heart disease -
Core facility-Cardiovascular nuclear medicine (human, dog)
ROlHL-17739-04 Acute myocardial infarct scintigraphy
(human, dogs, rats)
ROlHL-19289-03 Assessment of infusion methods for
myocardial mapping (dogs)
ROlHL-20674-02 Evaluation of cardiac function with
radioactive tracers
ROlHL-20677-02 Radionuclide studies in congenital heart
disease
ROlHL-21273-02
ROlHL-21276-02
imaging agents
R23HL-22004-01
Fibrinogen labeling with radiometals
Development of 99-mTc myocardial
•Excludes routine methodology OR covers only general projects which preclude
"Oriented significantly to atwve subject.
indexing at the specific level.
M Grant has subprojects describing s|
See Appendix for Investigator's name
Imaging and ECG studies in acute and
chronic IHD (human)
ROlHL-23983-01 Quantitative radiocardiography (human,
dogs)
(contd)
ipecific research aspects,
and grant number.
RAD
RADIOISOTOPE (NUCLEAR) MEDICINE, STABLE
(LABELED) ISOTOPE DIAGNOSIS
ROlHL-18738-02 Prevention of postoperative venous
thrombi (human, cattle)
ROlHL'20761-02 Study of cerebral blood flow with stable
xenon and computerized tomography
" ROlHL-21278-01 Abnormal cardiac wall motion viewed
ultrasonically (human, dogs, phantoms)
RADIOISOTOPE PHOTOSCANNING
SEE RAOIOAUTOGRAPHY. RADIONUCLIDE SCANNING*
RADIOISOTOPE TOMOGRAPHY
SEE RAOIOAUTOGRAPHY, RADIOISOTOPE TOMOGRAPHY*
RADIOISOTOPE TRACERS
SEE RADIOTRACER*
RADIOISOTOPES
SEE ALSO RADIOPHARMACOLOGY
SEE ALSO RADIOTRACER*
P01HL'11351-12 0009 Cellular and molecular
mechanisms of myocardial function - Myocardial membrane
surface coat (rats, rabbits)
P01HL12373-10 0018 Cardiopulmonary physiology and
pathophysiology ■ Biochemistry laboratory
ROlHL-15668-06 Extracorporeal respiratory gas exchange-
A new approach (dogs)
** P01HL-18576-03 0016 Thrombosis research program
project ■ Radiochemistiy core
RADIOISOTOPES, ACTINIDE SERIES, URANIUM
R01HL-19463-02 Pathophysiology of acute renal failure
(rats)
RADIOISOTOPES, BROMINE
P01HL1385M6 Cyclotron produced isotopes in biology
and medicine (human, animals)
P50HLUU7-08 C007 Specialized center of research in
thrombosis - Radioactive tracers in recognition of
intravascular coagulation (human, dogs)
RADIOISOTOPES, CARBON
POlHL-13851-16 Cyclotron produced isotopes in biology
and medicine (human, animals)
P01HL-18646-03 0008 Studies basic to heart
transplantation - Immunophysiology and early detection of
rejection (dogs)
R01HL-1893803 Pulmonary fatty acid and phospholipid
metabolism (rats)
ROlHL-2169701 Myocardium infarct sizing by 82Rb
emission tomography (dogs, human)
R01HL-22567-01 Validation of a cholesterol absorption
method in man
ROlHL-23618-01 Substrate metabolism in isolated
myocytes in shock (dogs, rats, guinea pigs)
RADIOISOTOPES, CHROMIUM
P50HL-14217-08 0052 Specialized center of research in
thrombosis - Radioisotope nuclear medicine section
(human, dog)
RADIOISOTOPES, FLUORINE
P01HL1385M6 Cyclotron produced isotopes in biology
and medicine (human, animals)
RADIOISOTOPES, GALUUM
P50HL-14147-08 0007 Specialized center of research in
thrombosis - Radioactive tracers in recognition of
intravascular coagulation (human, dogs)
** POlHL-1971702 0021 Response of the lung to injury -
Gallium lung scans in fibrosing alveolitis (hamsters)
ROlHL-2127302 Fibrinogen labeling with radiometals
RADIOISOTOPES, INDIUM
P50HL'14147-C8 0007 Specialized center of research in
thrombosis - Radioactive tracers in recognition of
intravascular coagulation (human, dogs)
P50HL'1421708 0052 Specialized center of research in
thrombosis - Radioisotope nuclear medicine section
(human, dog)
ROlHL-1880504 0005 Sudden cardiac death and the
onset of myocardial infarction - Sudden death survivors-
Radionuclide studies (human)
ROlHL'21273-02 Fibrinogen labeling with radiometals
RADIOISOTOPES, IODINE
POIHL'1237310 0005 Cardiopulmonary physiology and
pathophysiology - Characterization of fetal and neonatal
myocardium (human, cats)
P50HL-14147-08 0007 Specialized center of research in
thrombosis - Radioactive tracers in recognition of
intravascular coagulation (human, dogs)
P50HL'14217-08 0052 Specialized center of research in
thrombosis - Radioisotope nuclear medicine section
(human, dog)
R01HL1482e'05 External isotope assay of atherosclerosis
(rats, rabbits)
POIHL' 18646-03 0008 Studies basic to heart
transplantation - Immunophysiology and early detection of
rejection (dogs)
R01HL19127-03 Synthesis of molecules for myocardial
imaging (rats)
454
RADIOISOTOPES, NITROGEN
POlHL-1385116 Cyclotron produced isotopes in biology
and medicine (human, animals)
RADIOISOTOPES, OXYGEN
POlHL-13851-16 Cyclotron produced isotopes in biology
and medicine (human, animals)
** P01HL19737-02 0007 Cellular and molecular aspects of
respiratory physiology - Average oxygen tension of tissue
using radioisotopes (dogs)
RADIOISOTOPES, POTASSIUM
** POlHL-12157-11 0056 Functions and mechanisms of cell
membrane ion transport - Isotopic fluxes in synthetic
strands of heart cells (chick embryo)
POlHL-1215711 0057 Functions and mechanisms of cell
membrane ion transport - Electrophysiological
investigations of synthetic strands of heart muscles (rats)
RADIOISOTOPES, RUBIDIUM
R01HL-16553-05 Diagnosis of myocardial infarction by
radioisotopes (mice, rats, goats)
PSOHL-1 7665-04 0027 Study of ischemic heart disease -
Positron imaging of regional myocardial perfusion (human,
dog)
ROlHL-20943-02 Comparision of microsphere and RBC
behavior in vivo
ROlHL-21697-01 Myocardium infarct sizing by 82Rb
emission tomography (dogs, human)
RADIOISOTOPES, TECHNETIUM
P50HL-14147-08 0007 Specialized center of research in
thrombosis - Radioactive tracers in recognition of
intravascular coagulation (human, dogs)
P50HL-142 17-08 0052 Specialized center of research in
thrombosis - Radioisotope nuclear medicine section
(human, dog)
P50HL-17e69-04 0009 Ischemic heart disease center
(SCOR) - Infarct volume -99Tc stannous pyrophosphate
myocardial scintigrams (dogs, human)
P50HL-17669-04 0023 Ischemic heart disease center
(SCOR) - Patients with acute myocardial infarction and
myocardial ischemia (human)
P50HL-17670-04 0020 Study of ischemic heart disease -
Radionuclide evaluation of coronary artery disease (human,
dog)
R01HL18805-04 0005 Sudden cardiac death and the
onset of myocardial infarction - Sudden death survivors-
Radionuclide studies (human)
RAD
Thallium and antlmyosin in
Canine models of ischemia and
Thallium and antlmyosin in
Human studies-Ischemia and
Synthesis of molecules for myocardial
Fibrinogen labeling with radiometals
Development of 99-mTc myocardial
ROlHL-19127-03
imaging (rats)
ROlHL.21273-02
ROlHL-21276-02
imaging agents
ROlHL-21518-01 Improvement in regional ventilation-
perfusion resolution (human)
ROlHL-2 16 84-02 0001 Radionuclide infarct sizing and
therapy evaluation - Evaluating preservation of ischemic
myocardium by radioisotope methods (dog)
R0IHL-2ie84-02 0002 Radionuclide infarct sizing and
therapy evaluation ■ Evaluating myocardial imaging agents
in global and regional ischemia (rabbits)
R01HL-2ie84-02 0004 Radionuclide Infarct sizing and
therapy evaluation - Image analysis-Kinetics of infarction,
ventricular function (human, animal)
ROlHL-21684-02 0005 Radionuclide infarct sizing and
therapy evaluation - Clinical evaluation of radioisotope
imaging methods for quantifying infarct size
ROlHL-21690-02 Sequential multinuclide study of acute
infarction (human, dogs)
ROlHL-2170701 Quantification of infarct size by emission
tomography (human, dogs)
ROlHL-21793-02 Functional infarct size by gated
radioangiography (human, dogs)
RADIOISOTOPES, THALLIUM
ROlHL-16553-05 Diagnosis of myocardial infarction by
radioisotopes (mice, rats, goats)
P50HL-17655-04 0011 Study of ischemic heart disease -
Core facility-Cardiovascular nuclear medicine (human, dog)
P50HL-I7670-04 0020 Study of ischemic heart disease -
Radionuclide evaluation of coronary artery disease (human,
dog)
R0IHL18805-04 0005 Sudden cardiac death and the
onset of myocardial infarction - Sudden death survivors-
Radionuclide studies (human)
P50HL-2 10 06-02 0005 Specialized center of research in
arteriosclerosis - Regional myocardial perfusion in patient
with coronary artery disease (also dogs)
ROlHL-21684-02 0002 Radionuclide infarct sizing and
therapy evaluation - Evaluating myocardial imaging agents
in global and regional Ischemia (rabbits)
ROlHL-21684-02 0004 Radionuclide infarct sizing and
therapy evaluation - Image analysis-Kinetics of infarction,
ventricular function (human, animal)
ROlHL-21690-02 Sequential multinuclide study of acute
infarction (human, dogs)
ROlHL-21707-01 Quantification of infarct size by emission
tomography (human, dogs)
M R01HL-21751-02 Thallium and antlmyosin in ischemia and
infarction
Thallium and antlmyosin in
' In vitro models of ischemia and
ROlHL-21751-02 0002
ischemia and infarction
infarction
ROlHL-21751-02 0003
ischemia and infarction
infarction
ROlHL-21 793-02 Functional infarct size by gated
radioangiography (human, dogs)
RADIOISOTOPES, XENON
•* POlHL-07896-15 0055 Environmental biomedical research
program - Cerebral blood flow by Xenon-133 inhalation
(human)
ROlHL-10009-13 Regional lung function in man
ROlHL-1091410 Renal sodium transport in experimental
aldosteronism (dogs)
P50HL 21006-02 0005 Specialized center of research in
arteriosclerosis - Regional myocardial perfusion In patient
with coronary artery disease (also dogs)
ROlHL-21518-01 Improvement in regional ventilation-
perfusion resolution (human)
RADIOLOGICAL HEALTH, RADIATION HAZARDS
POIHL- 15832-06 0007 Chemical-structural predispositions
to lung injury - Inactivation of vasoactive agents by the
lung (human, rats, cats, dogs)
RADIONUCUDE SCANNING
SEE RAOIOAUTOGRAPHY. RADIONUCLIDE SCANNING*
RADIONUCUDES
SEE RADIOISOTOPES
RADIOPHARMACOLOGY
R01HL-12740-10 Hypocholesterolemic agents-
Stereochemistry (rats)
POlHL-13851-16 Cyclotron produced isotopes in biology
and medicine (human, animals)
P50HL-14147-08 0007 Specialized center of research in
thrombosis - Radioactive tracers in recognition of
intravascular coagulation (human, dogs)
R01HL-160370e Molecular properties of cardiac
adrenergic receptors
P50HL- 17655-04 0011 Study of ischemic heart disease -
Core facility-Cardiovascular nuclear medicine (human, dog)
P50HL17665-04 0027 Study of ischemic heart disease -
Positron imaging of regional myocardial perfusion (human,
dog)
ROlHL-17739-04 Acute myocardial infarct scintigraphy
(human, dogs, rats)
** ROlHL-18744-03
drug analogs
** R01HL19127-03
imaging (rats)
ROlHL-20674-02
radioactive tracers
** ROlHL-21273-02 Fibrinogen labeling with radiometals
ROlHL-21276-02 Development of 99-mTc myocardial
imaging agents
ROlHL-21684-02 0002 Radionuclide infarct sizing and
therapy evaluation - Evaluating myocardial imaging agents
In global and regional ischemia (rabbits)
ROlHL-21684-02 0004 Radionuclide infarct sizing and
therapy evaluation - Image analysis-Kinetics of infarction,
ventricular function (human, animal)
ROlHL-21690-02 Sequential multinuclide study of acute
Infarction (human, dogs)
ROlHL-21697-01 Myocardium infarct sizing by 82Rb
emission tomography (dogs, human)
R01HL-217S1-02 0002 Thallium and antlmyosin in
ischemia and infarction - Canine models of ischemia and
Preparation of radiopharmaceuticals from
Synthesis of molecules for myocardial
Evaluation of cardiac function with
infarction
ROlHL-21751-02 0003
ischemia and infarction
infarction
Thallium and antlmyosin in
- Human studies-Ischemia and
ROlHL-21751-02 0001
ischemia and infarction
infarction (rats, mice)
'Excludes routine methodokigy OR covers only general projects which preclude indexing at the specific level
"Orientad significantly to above subject.
RADIOSCOPY
SEE RADIOGRAPHY. FLUOROSCOPY*
RADIOSENSITIVITY
SEE RADIATION SENSITIVITY
RADIOTHERAPY
SEE RADIATION THERAPY
RADIOTRACER*
SEE ALSO HYDROGEN, TRfTIUM*
SEE ALSO IMMUNOLOGICAL TESTS AND IMMUNOASSAY,
RADIOIMMUNOASSAY*
SEE ALSO RAOIOAUTOGRAPHY, RADIOISOTOPE TOMOGRAPHY*
R01HL-10914-I0 Renal sodium transport in experimental
aldosteronism (dogs)
ROlHL-14820-07 Factors affecting physiology of biological
membranes (human)
POlHL-15596-05 0001 Coagulation, fibrinolysis,
hemostasis and hepatitis - Defibrination (human)
R01HL-18679-04 Synthetic protease inhibitors
ROlHL-18744-03 Preparation of radiopharmaceuticals from
drug analogs
ROlHL-1893803 Pulmonary fatty acid and phospholipid
metabolism (rats)
R23HL-19594-01 Tropocollagen and tropoelastin uptake in
lung cells (human)
ROlHL-23618-01 Substrate metabolism in isolated
myocytes in shock (dogs, rats, guinea pigs)
(contd)
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
RAO
HADIOTRACERS, OOUBIE (MULTIPLE)*
ROIHL 1388S08 9002 Cyslic libiosis «nd pulmonam
dISHsa ComputM cot« lacility (human)
P50HL 142300? 0098 A/S SCOR Lipids, alheioscletosis
and thrombosis Molecular properties ol factor VIII (cattle,
human, mice)
ROIHI I880b04 0005 Sudden cardiac death and the
onset ot myocardial inlarction Sudden death survivors
Radionuclide studies (human)
ROIHL 22S67 01 Validation ot a cholesterol absorption
method in man
RAGWEED
SEE PUNTS, ANGIOSPERMS, RAGWEED*
RAiMAN SPECTRA
SEE CHEMISTRY, ANALYTICAL METHODS, SPECTROMETRY.
RAMAN*
RAPHE NUCLEUS, DORSAL
SEE BRAIN, MESENCEPHALON. RAPHE NUCLEUS. DORSAL
RAPID DIAGNOSIS
SEE DIAGNOSTIC TESTS, RAPID DIAGNOSIS*
RARE EARTH METALS
SEE METALS. RARE EARTHS
RARE EARTHS
SEE METALS, RARE EARTHS
RARE GAS ELEMENTS
SEE GAS ELEMENTS, INERT
RATE OF ADMINISTRATION, DRUGS
SEE DOSAGE AND ROUTE, RATE AND DURATION OF
ADMINISTRATION
RATS (LABORATORY)
SEE MAMMALS, RODENTS, MYOMORPHA, RATS
(UBORATORY)*
RAUSCHER LEUKEMIA VIRUS
SEE VIRUSES, ONCORNA, LEUKEMIA MOUSE RAUSCHER
RAUWOLFIA ALKALOIDS
SEE ALKALOIDS, RAUWOLFIA TYPE, RAUWOLFIA
RAUWOLFINE
SEE ALKALOIDS, RAUWOLFIA TYPE, AJMALINE
RAYNAUD'S DISEASE AND PHENOMENON
SEE CARDIOVASCUUR DISORDERS, RAYNAUD'S DISEASE AND
PHENOMENON
REACTION DYNAMICS, KINETICS, MECHANISMS
SEE CHEMICAL REACTIONS (DYNAMICS)
REACTION RATES (CHEMISTRY)
SEE CHEMICAL REACTION RATES
REACTION SITES, CHEMICAL
SEE CHEMICAL REACTION SITES
REACTIVE HYPEREMIA
SEE CARDIOVASCULAR FUNCTION, BLOOD FLOW. REACTIVE
HYPEREMIA
REACTIVE PSYCHOTIC DEPRESSION
SEE PSYCHOSIS, DEPRESSIVE. REACTIVE PSYCHOTIC
DEPRESSION
REAGENTS
SEE INDICATORS AND REAGENTS
REAGIN
SEE HYPERSENSITIVITY, SKIN SENSITIZING ANTIBODY
RECEPTOR SITES, ENZYMES
SEE ENZYME STRUCTURE
RECEPTORS OF NON-SENSORY STIMULI
SEE BIOLOGICAL TRANSPORT, TRANSPORT PROTEINS (SEE
ALSO SPECIFICS)
SEE DRUGS RECEPTORS
SEE ENDOCRINOLOGY. HORMONE BINDING PROTEINS
SEE ENDOCRINOLOGY, HORMONE RECEPTORS
SEE GLOBULINS, CORTICOSTEROID BINDING GLOBULIN
SEE HALOPROTEINS, THYROXINE BINDING PROTEINS
SEE NEUROTRANSMITTERS RECEPTORS
RECEPTORS OF SENSORY STIMULI
SEE EYE, PHOTORECEPTORS
SEE NERVOUS SYSTEM, AFFERENT NERVES
SEE SENSE ORGANS
RECESSIVE DISORDERS, GENETIC
SEE GENETIC DISORDERS, AUTOSOMAL RECESSIVE
CONDITIONS
RECOMBINANT DNA
SEE NUCLEIC ACIDS. UNNATURAL NUCLEIC ACIDS, HYBRID
NUCLEIC ACIDS
RECOMBINANT DNA, ARTIFICIALLY INDUCED
SEE GENETIC MANIPUUTION
RECOMBINATION
SEE GENETICS, RECOMBINATION
455
RECONSTITUTION OF ENZYMES
Sff EN/YMf RfCONSllIUIION
SEE PROUINS RfCONSllIUIION
RECONSTITUTION OF MEMBRANES
SEf MfMBRANE SYNTHESIS AND KFCONSIIIUTION
RECONSTITUTION OF PROTEINS
SEE PROUINS RECONSIIIUTION
RECORD SYSTEMS (HEALTH)
SEE HEALTH RECORDS
RECORDING AND RECORDING SYSTEMS
SEE BIOMEDICAL SYSTEMS AUTOMATED, ELECTRONIC
RECORDING SYSTEMS
SEE BIOMEDICAL SYSTEMS AUTOMATED, MAGNETIC
RECORDING SYSTEMS
RECORDS, MEDICAL
SEE HEALTH RECORDS
RECREATION
SEE OCCUPATIONS, RECREATION
RECRUITMENT NEURAL
SEE NEUROPHYSIOLOGY, NEURAL RECRUITMENT
RECTAL SALT GLAND
SEE BODY FLUID BALANCE, IONIC, SALT GLAND
RECURRENCE OF DISEASE
SEE DISEASE RECURRENCE
RED CELL GHOSTS
SEE MEMBRANE, ERYTHROCYTE GHOST AND MEMBRANE
RED CROSS
SEE HEALTH AND SCIENTIFIC ORGANIZATIONS, VOLUNTARY
HEALTH ORGANIZATIONS, RED CROSS
REDOX
SEE OXIDATION-REDUCTION
REDOX PROTEINS, LOW/ MOLECULAR VI/EIGHT
SEE RESPIRATORY PROTEINS, REDOXINS
REDOXINS
SEE RESPIRATORY PROTEINS. REDOXINS
REDUCING DIET
SEE NUTRITION. DIET THERAPEUTIC, REDUCING DIET
REDUCTION
SEE OXIDATION-REDUCTION, REDUCTION
REFERRAL AND CONSULTATION
SEE HEALTH CARE SERVICES, REFERRAL AND CONSULTATION
REFERRAL CENTERS
SEE BIOMEDICAL REGISTRIES AND REFERRAL CENTERS
REFERRAL CENTERS, CHEMICAL AND DRUG
SEE CHEMICAL AND DRUG REGISTRIES, REFERRAL CENTERS
AND RESOURCES
REFERRAL CENTERS, IMMUNOLOGICAL
PREPARATIONS
SEE IMMUNOLOGICAL PREPARATIONS (GENERAUdNCLUDING
CERTIFICATION AND STANDARDIZATION)
REFLEX
SEE NEUROPHYSIOLOGY, REFLEX
REFRIGERATION ANESTHESIA
SEE SENSORY DEPRESSION, ANESTHESIA, REFRIGERATION
REGENERATION
SEE GROWTH AND DEVELOPMENT, REGENERATION
REGENERATION, NERVOUS SYSTEM
SEE NERVOUS SYSTEM REGENERATION
REGIONAL ANESTHESIA
SEE SENSORY DEPRESSION, ANESTHESIA CONDUCTION
REGIONAL MEDICAL PLANNING
SEE HEALTH CARE (SERVICES)(RESOURCES)PUNNING,
REGIONAL MEDICAL PLANNING
REGISTRIES
SEE GENETIC REGISTRIES AND REFERRAL CENTERS
SEE INFORMATION SYSTEMS (INCL BANKS AND CENTERS)
SEE TISSUE (CELL) CULTURE, CELL CULTURE COLLECTIONS
BANKS AND REGISTRIES
REGISTRIES, BIOMEDICAL
SEE BIOMEDICAL REGISTRIES AND REFERRAL CENTERS
REGISTRIES, BLOOD
SEE BLOOD PRESERVATION, BLOOD BANKS, CENTERS-
RESOURCES-REGISTRIES
REGISTRIES, CHEMICAL AND DRUG
SEE CHEMICAL AND DRUG REGISTRIES, REFERRAL CENTERS
AND RESOURCES
REGISTRIES, DISEASE (CLINICAL DISEASE)
SEE HEALTH RECORD SYSTEMS, PATIENT (DISEASE)
REGISTRIES
REGISTRIES, HEALTH SCIENCES MANPOWER
Sl( HIAKH SCIFNCIS PROK SMON', HIAIIH 'XIINCf.
MANPOWfR DAIA AND RIOIMRIIS
REGISTRIES, HISTOCOMPATIBILITY, TYPING-
MATCHING
SEf TISSUE COMPATIBILITY TRANSPUNIAIION RESOURCES.
RFFfRRAl CfNTERS AND RfCISTRIfS
REGISTRIES, IMMUNOLOGICAL PREPARATIONS
SEE IMMUNOLOGICAl PREPARATIONS (GtNERADdNCLUDING
CERTIFICATION AND STANDAROI/AIION)
REGISTRIES, PATIENT (OR CLINICAL DISEASE)
SEE HEALTH RECORD SYSTEMS, PATIENT (DlSfASf)
REGISTRIES
REGISTRIES, TISSUE
SEE TISSUE RESOURCES, REGISTRIES
REGISTRIES, TRANSPLANTATION
SEE TISSUE COMPATIBILITY TRANSPLANTATION RESOURCES,
REFERRAL CENTERS AND REGISTRIES
REGITINE
SEE IMIDAZOLES, PHENTOLAMINE
REGULATION (SELF) OF (VISCERAL) RESPONSES
SEE PSYCHOLOGY, CONDITIONING, AUTOGENIC AND INTERNAL
CONTROL
REGULATORY CENTERS OF BRAIN
SEE BRAIN, REGULATORY CENTERS (GENERAL)
REGULATORY GENE
SEE GENETICS, GENES, OPERON, REGULATORY GENE
REHABILITATION NONPSYCHOSOCIAL
SEE HEALTH CARE SERVICES, REHABILITATION
NONPSYCHOSOCIAL
REHABILITATION PSYCHIATRIC
SEE MENTAL HEALTH SERVICES, REHABILITATION
PSYCHOSOCIAL
REHABILITATION PSYCHOSOCIAL
SEE MENTAL HEALTH SERVICES, REHABILITATION
PSYCHOSOCIAL
REHABILITATION VOCATIONAL
SEE HEALTH CARE SERVICES, REHABILITATION VOCATIONAL
REINFORCEMENT (CONDITIONING)
SEE PSYCHOLOGY, CONDITIONING, REINFORCEMENT
REINFORCEMENT (LEARNING)
SEE PSYCHOLOGY, LEARNING, REINFORCEMENT
RELAXATION
SEE PSYCHIC ACTIVITY LEVEL, RELAXATION
REMEDIAL TRAINING
SEE EDUCATION, SPECIAL (REMEDIAL)
REMISSION OF DISEASE
SEE DISEASE REMISSION
REMOTE SENSORS
SEE BIOMEDICAL SYSTEMS AUTOMATED, TELEMETERING AND
REMOTE SENSING
RENAL ARTERY
SEE KIDNEY CIRCUUTION, RENAL ARTERY
RENAL ARTERY OBSTRUCTION
SEE KIDNEY-CIRCULATORY DISORDERS, RENAL ARTERY
OBSTRUCTION
RENAL CIRCULATION
SEE KIDNEY CIRCULATION
RENAL CORTEX
SEE KIDNEY, RENAL CORTEX
RENAL FAILURE
SEE KIDNEY DISORDERS, RENAL FAILURE
RENAL HYPERTENSION
SEE KIDNEY-CIRCULATORY DISORDERS, RENAL
HYPERTENSION
RENAL HYPERTROPHY
SEE KIDNEY DISORDERS, RENAL HYPERTROPHY
RENAL ISCHEMIA AND HYPOXIA
SEE KIDNEY-CIRCUUTORY DISORDERS, RENAL ISCHEMIA
AND HYPOXIA
RENAL MEDULLA
SEE KIDNEY, RENAL MEDULLA
RENAL TUBULAR ACIDOSIS
SEE METABOLIC DISORDERS (INBORN), RENAL TUBUUR
ACIDOSIS
RENAL TUBULAR TRANSPORT
SEE KIDNEY FUNCTION, RENAL TUBULAR TRANSPORT
RENAL TUBULES
SEE KIDNEY, RENAL TUBULES
(contd)
*E»clud«s routine methodology OR covers only general projects which preclude
**0iiented significantly to above subiect.
Indexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
REN
RENAL VEINS
SEE KIDNEY CIRCUUTION, RENAL VEINS
RENIN
SEE PEPTIDES. VASOACTIVE PEPTIDES. RENIN
RENIN-ANGIOTENSIN-ALDOSTERONE
IMBALANCE, BARTTER'S SYNDROME
SEE METABOLIC DISORDERS INBORN. BARTTERS SYNDROME
RENIN-ANGIOTENSIN SYSTEM
SEE PEPTIDES. VASOACTIVE PEPTIDES, RENIN-ANGIOTENSIN
SYSTEM
RENOGRAPHY (X-RAY)
SEE KIDNEY VISUALIZATION*
RENOPRIVAL HYPERTENSION
SEE KIDNEYCIRCULATORY DISORDERS, RENOPRIVAL
HYPERTENSION
REPLACEMENT, TRANSFUSION
SEE BLOOD TRANSFUSION, EXCHANGE
REPLICATION
SEE NUCLEIC ACIDS SYNTHESIS
REPLICATION, VIRAL
SEE VIRUS DEVELOPMENT, REPLICATION
REPOSITORIES, TISSUE
SEE TISSUE RESOURCES, REGISTRIES
REPRESSORS
SEE GENETICS, GENETIC REGULATION, GENETIC INDUCTION-
REPRESSION-DEREPRESSION, REPRESSORS
REPRODUCTIVE AND SEX DEVELOPMENT
DISORDERS
P50HL-14141-05 0007 SCOR for atherosclerosis in
childhood - Relation of lipid valves to sexual maturation at
puberty (human)
REPRODUCTIVE AND SEX DEVELOPMENT
DISORDERS, HYPOGONADISM
P60HL-16008-06 0015 Wayne State University
comprehensive siclile cell center - Trace elements in sickle
cell disease (human)
REPRODUCTIVE HORMONES, CHORIONIC
SOMATOMAMMOTROPIN
SEE ALSO PITUITARY-DIENCEPHALON HORMONES, PROLACTIN
ROlHL-20939-02 Regulation of fetal hemoglobin in
humans
REPRODUCTIVE HORMONES, GONADOTROPINS
CHORIONIC
ROlHL-20939-02 Regulation of fetal hemoglobin in
humans
REPRODUCTIVE HORMONES, PLACENTAL
HORMONES
SEE ALSO REPRODUCTIVE HORMONES, CHORIONIC
SOMATOMAMMOTROPIN
SEE ALSO REPRODUCTIVE HORMONES, GONADOTROPINS
CHORIONIC
P50HL-14214-07 0024 Newborn lung center for hyaline
membrane disease - Synthesis and receptors for ACTH in
fetal lung (human)
REPRODUCTIVE HORMONES, SEX HORMONES
SEE ALSO ANDROSTANE SERIES, ANDROGENS
SEE ALSO ESTRATRIENE SERIES, ESTROGENS
SEE ALSO PROGESTERONE
SEE ALSO PROGESTINS
P50HL-14141-05 0007 SCOR for atherosclerosis in
childhood - Relation of lipid valves to sexual maturation at
puberty (human)
P50HL-14237-07 0005 Support for arteriosclerosis center
- Genetic determinants of apolipoprotein variability in
lipoproteins (human)
** P01HL-16387-04 0002 The blood vessel and
thrombogenesis ■ Hormonal effects on thrombogenesis
(rats, rabbits)
ROIHLI 7721-04 Effect of sex hormones on vascular
connective tissue (rats)
" ROlHL-1 7865-04 Studies on aging-Effects of sex
hormones (rats, dogs)
ROlHL-18002-03 Circulatory shock, trauma and RE-system
function (rats)
ROlHL-20645-01 Etiology of myocardial infaction (human)
** ROlHL-22040-01 Regulation of lysyl-cross-lmking in
vascular tissue (rats, turkeys)
ROlHL-22225-01 Hormonal regulation of blood pressure
and blood flow (human, animals)
R01HL-22873-0I Adrenoceptor Interconversion and
hormone homeostasis
REPRODUCTIVE SYSTEM (GENERAL)
R01HL19066-03 Synthesis and evaluation of
prostaglandin metabolites (guinea pigs)
REPRODUCTIVE SYSTEM, GONADS
SEE ALSO REPRODUCTIVE AND SEX DEVELOPMENT
DISORDERS
SEE ALSO REPRODUCTIVE SYSTEM FEMALE. OVARY
•Excludes routine methodology OR covers only general projects which preclude indexing
Oriented significantly to above subject.
ROlHL-14913-06
(rats)
456
Hypertension-Genetic influence of kidney
REPRODUCTIVE SYSTEM FEMALE, MAMMARY
GLANDS
SEE ALSO BODY FLUIDS. MILK
SEE ALSO NEOPUSMS OF REPRODUCTIVE SYSTEM, BREAST
NEOPLASMS
R01HL-13901-08 Ontogeny, ultrastructure, function in
lymphatic system (birds, fish, mammals)
REPRODUCTIVE SYSTEM FEMALE, MAMMARY
GLANDS, LACTATION
ROIHL 13901-08 Ontogeny, ultrastructure, function in
lymphatic system (birds, fish, mammals)
REPRODUCTIVE SYSTEM FEMALE, OVARY
R01HL-02033-23 Regulation of cholesterol esters in blood
and tissues (rat, cattle, human)
R01HL14990-07 Lipid transport in avian species
(chickens)
REPRODUCTIVE SYSTEM FEMALE, UTERUS
SEE ALSO REPRODUCTIVE SYSTEM SURGERY FEMALE
HYSTERECTOMY
** R0IHL-03941-18 Uterine blood flow and changes in
pregnancy (sheep)
** P01HL-06285-18 0133 Cardiovascular-respiratory
physiology and biochemistry - Decreased uterine blood flow
and fetal development (lambs)
ROlHL-12557-09 Effects of steroids and pregnancy on
arteries and veins (guinea pigs)
ROIHL- 136 34-08 Renal hypertension in pregnancy (sheep)
ROlHL-15655-05 Blood flow and gas exchange in placenta
and lungs (sheep) rabbits)
" P01HL-I5835-06 0002 Study of muscles related to heart
disease - Proteins of smooth muscle system (cattle,
rabbits)
ROlHL-15839-05 Physiological role of isorenin and
kallikrein (animals)
R01HL191 15-02 Hormonal control of tracheobronchial
cyclic AMP (rats, guinea pigs)
ROlHL-21308-01 Prostaglandins and local control of the
circulation (rats, dogs)
R23HL-21914-01 Studies of vasomotor control (rats)
ROlHL-22225-01 Hormonal regulation of blood pressure
and blood flow (human, animals)
ROlHL-23602-01 Physiology of renin, aldosterone and
prostaglandin (human, rats, dogs)
REPRODUCTIVE SYSTEM MALE, EPIDIDYMIS AND
DUCTS
ROlHL-18601-01 Regulation of neurotransmitter release by
adenosine (rats)
REPRODUCTIVE SYSTEM DISORDERS (GENERAL)
SEE ALSO PREGNANCY DISORDERS
ROlHL-11614-11 Trace elements in nutrition (chickens,
rats, human)
REPRODUCTIVE SYSTEM DISORDERS FEMALE,
UTERINE DISORDERS
P01HL-06285-18 0135 Cardiovascular-respiratory
physiology and biochemistry - Beta-adrenergic agents and
fetal cardiovascular dynamics (lambs)
ROlHL-22258-01 New aspects of pharmacology related to
carbonic anhydrase
REPRODUCTIVE SYSTEM DISORDERS MALE,
PROSTATE DISORDERS
SEE ALSO NEOPLASMS OF REPRODUCTIVE SYSTEM MALE,
PROSTATE NEOPLASMS
ROlHL-19839-09 Factors in youth predisposing to chronic
diseases (former college students)
REPRODUCTIVE SYSTEM DISORDERS
CHEMOTHERAPY
SEE ALSO PREGNANCY DISORDERS CHEMOTHERAPY
SEE ALSO REPRODUCTIVE SYSTEM PHARMACOLOGY
P50HL-14141-05 0002 SCOR for atherosclerosis in
childhood - Intrauterine environment of proband group
(human)
REPRODUCTIVE SYSTEM PHARMACOLOGY
SEE ALSO PREGNANCY DISORDERS CHEMOTHERAPY
SEE ALSO REPRODUCTIVE SYSTEM DISORDERS
CHEMOTHERAPY
** RC1HL-1255709 Effects of steroids and pregnancy on
arteries and veins (guinea pigs)
ROlHL-14526-07 Oral contraceptives and hypertension
(rats)
REPRODUCTIVE SYSTEM SURGERY FEMALE,
HYSTERECTOMY
ROlHL-201 79-02 Epidemiology of sudden cardiac death
among women
REPTILE POISONS
SEE TOXICOLOGY, ANIMAL POISONS, REPTILE
REPTILES*
ROlHL-18868-03 Development of vertebrate vascular
control systems (reptiles, amphibians)
at the specific level.
M Grant has subprojects describing specific research aspects
See Appendix for investigator's name and grant number.
RES
REPTILES, TURTLES*
R01HL-04457-20 Cellular aspects of active transport (fish,
rabbits, anurans, turtles)
RESEARCH BIOMEDICAL
SEE HEALTH SCIENCES RESEARCH (GENERAL)*
RESEARCH FACILITIES
SEE BIOMEDICAL ENGINEERING, INSTRUMENTATION CENTERS
SEE BIOMEDICAL FACILITIES
SEE CLINICAL RESEARCH CENTERS
SEE COMPUTER CENTERS
SEE GENERAL MEDICINE STUDY SECTION
SEE STATISTICAL SERVICE AND CENTERS
RESEARCH MANPOWER REVIEW COMMITTEE
R23HL-19573-01 Studies on pulmonary serotonin (mice)
R23HL-19584-01 Alveolar macrophage responses to toxic
particle exposure (guinea pigs, human)
R23HL-19594-01 Tropocollagen and tropoelastin uptake in
lung cells (human)
R23HL-I9605-01 Lipid requirement of the "lung mono-
oxygenase system (rabbits)
R23HL19619-01 Sem and x ray analysis in human
pulmonary pathology
R23HL-20576-01 Airway turbulence and pulmonary oxygen
exchange
RESEARCH PROGRAM ANALYSIS-EVALUATION-
PLANNING
SEE HEALTH SCIENCES RESEARCH ANALYSIS-EVALUATION-
PLANNING
RESERPINE
SEE ALKALOIDS, RAUWOLFIA TYPE, RESERPINE
RESIDENCE CHARACTERISTICS
SEE SOCIOENVIRONMENT, RESIDENCE CHARACTERISTICS,
HOUSING
RESIDENTIAL HEALTH CARE FACILITIES
SEE HEALTH CARE FACILITIES, RESIDENTIAL
RESIDENTIAL MOBILITY
SEE SOCIOENVIRONMENT, RESIDENTIAL MOBILITY
RESIDUE DIETARY
SEE NUTRfflON, OICTARY CONSTITUENTS, DIETARY RESIDUES-
FIBERS
RESINS
SEE MOLECUUR CONDENSATIONS. RESINS
RESONANCE SPECTROMETRY, ELECTRON SPIN
SEE CHEMISTRY, ANALYTICAL METHODS, SPECTROMETRY
ESR*
RESONANCE SPECTROMETRY, NUCLEAR
AAAGNETIC
SEE CHEMISTRY, ANALYTICAL METHODS, SPECTROMETRY
NMR*
RESOURCES, BIOMEDICAL (GENERAL)
SEE BIOMEDICAL RESOURCES (GENERAL)
RESOURCES, CHEMICAL AND DRUG
SEE CHEMICAL AND DRUG REGISTRIES, REFERRAL CENTERS
AND RESOURCES
RESOURCES, HISTOCOMPATIBILITY TYPING-
MATCHING
SEE TISSUE COMPATIBILITY-TRANSPLANTATION RESOURCES
REFERRAL CENTERS AND REGISTRIES
RESOURCES, IMMUNOLOGICALS
SEE IMMUNOLOGICAL PREPARATIONS (GENERADdNCLUDING
CERTIFICATION AND STANDARDIZATION)
RESOURCES, TISSUE
SEE TISSUE RESOURCES. REGISTRIES
RESOURCES AND SERVICES IN HEALTH CARE
UTILIZATION, AVAILABILITY AND
DISTRIBUTION
SEE HEALTH CARE (SERVICESXRESOURCES) UTILIZATION,
AVAIUBILITY AND DISTRIBUTION OF SERVICES AND
RESOURCES
RESPIRATION
SEE RESPIRATORY FUNCTION, RESPIRATION
RESPIRATION INTERNAL
SEE ALSO OXIDATIVE PHOSPHORYUTION
SEE ALSO OXIDOREDUCTASES
SEE ALSO RESPIRATORY GAS ANALYZERS*
SEE ALSO RESPIRATORY PROTEINS (GENERAL)
R01HL-CC082-3C Transmembrane movements (barnacles,
frogs, rats)
P01HL-06285-18 0195 Cardiovascular-respiratory
physiology and biochemistry - Thyroid thermogenesis and
sodium transport (rats)
P01HL-07896-15 0063 Environmentai biomedical research
program - Oxygen toxicity (baboons)
POlHL-08899-14 0010 Tolerance to respiratory gases in
health and disease • High oxygen pressure in septic shock
(human)
(contd)
RES
POIHI 08899 14 0014 Toleiance to lespuatoiy jases in
hsilth and disease Cellulai and lenal lesponses to
liypeicapnia and hypocapnia (dots)
ROIHL 12997 0? Myocaidial delects induced by potassium
depletion (human, lats. cats)
• ROIHL 13341 06 Lymph An indication ol splanchnic tissue
respiiation (dogs, human, lats)
POIHI 13737 07 0031 Assisted circulation Myocardial
ischemia Biochemical chanies (dogs)
ROIHL 1398905 Role ol water in respuatiory protein
stnicture
ROIHL 14483 08 Energy conservation in heart
mitochondria (cattle. E coll. human)
PbOHL 1506! 07 0002 Response ol lung to iniury
Oxidative metabolism, phospholipid synthesis, and response
to toxins (rats)
'* ROIHL 15104 07 A mechanism lor oxidative
phosphorylation
ROIHL 15273 06 Metabolism ol pulmonary surlactant
(human, rats)
POIHL 1583506 0013 Study of muscles related to heart
disease Cardiac bioenergetics (rats)
ROIHL 16931 04 Red cell storage and transfusion
(human, animals)
P50HL 17670-04 0022 Study of ischemic heart disease -
Myocardial metabolism in hypoxia and recover (rabbit,
toad, dog)
ROIHL 17736 04 Metabolic change during cardiac
ischemia (rats, dogs)
•* R01HL18304 03 FT infrared spectroscopy of heart muscle
energetics (cattle)
ROIHL 1830904 Oxygen transport-Hemoglobins with
modified hemes (horse)
** ROlHL-18351-03 Brain metabolism, acid-base balance.
and respiration
** POIHL 18708-03 0009 Oxygen, energy and contractility in
cardiac tissue - Regulation ol oxygen utilization of cardiac
tissue (rats, rabbits)
** P01HL1870803 0010 Oxygen, energy and contractility in
cardiac tissue - Tissue oxygen utilization (rats, dogs)
R01HL1898401 P50 effect on exercise limit in stable
angina (human)
ROlHL-1929903 Myoglobin and oxygen supply to heart
and muscle cells (rats, pigeons)
ROlHL-1935203 Respiratory heat and water loss in
neonates
R01HL1941403 Protection of myocardium during cardiac
surgery (dogs. cats, human)
** POlHL-19737-02 0006 Cellular and molecular aspects of
respiratory physiology - Tissue oxygenation and
mitochondrial respiratory activity (sheep)
ROlHL-20610-02 Nerve growth factor and obstructive
cardiomyopathy (dogs)
** ROlHL-21849-02 Control of sodium transport and cellular
respiration (toad bladder)
ROlHL-2191201 Biosynthesis of lipoic acid and
atherosclerosis (birds, chick embryos)
ROlHL-23153-01 Mechanisms of altered CA20 transport in
ischemic heart (dog. rabbit)
** ROlHL-2316601 Pathology of mitochondria in ischemic
myocardium (rats, cattle)
RESPIRATION INTERNAL, AEROBIOSIS
SEE ALSO MICROORGANISMS. AEROBES
ROlHL-1856003 Cardiovascular adaptation to stress
(miniature swine)
ROlHL-23240-01 Pulmonary vascular muscle metabolism
and contractility (rats, cattle)
RESPIRATION INTERNAL, ANAEROBIOSIS
SEE ALSO MICROORGANISMS. ANAEROBES
" ROlHL-11907-08 Mechanisms of physiological responses
to exercise (human, dogs)
RESPIRATORS
SEE RESPIRATORY ASSIST AND OXYGEN ADMINISTRATION.
RESPIRATORS
RESPIRATORY AIRFLOW DISORDERS
SEE RESPIRATORY DISORDERS. RESPIRATORY AIRFLOW
DISORDERS
RESPIRATORY AIRFLOW MEASUREMENTS
SEE RESPIRATORY DISORDERS DIAGNOSIS. RESPIRATORY
AIRFLOW MEASUREMENTS*
RESPIRATORY AIRWAY CLEARANCE
SEE RESPIRATORY FUNCTION, RESPIRATORY AIRWAY
CLEARANCE
RESPIRATORY AIRWAY PRESSURE
SEE RESPIRATORY FUNCTION, RESPIRATORY AIRWAY
PRESSURES
RESPIRATORY AIRWAY VOLUME
SEE RESPIRATORY FUNCTION, RESPIRATORY AIRWAY VOLUME
RESPIRATORY ANESTHESIA (INHALATION
ANESTHESIA)
SEE SENSORY DEPRESSION, At«ESTHESIA (GENERAL),
INHALATION
RESPIRATORY ASSIST, MECHANICAL
SEE RESPIRATORY ASSIST AND OXYGEN ADMINISTRATION,
RESPIRATORS
457
RESPIRATORY ASSIST AND OXYGEN
ADMINISTRATION
SLl Also CARDIOVASCULAR SURGERY, CIRCUUIORY
ASSIST, BIOOD OXYGENATORS
SEE ALSO CARDIOVASCULAR SURGERY, CIRCULATORY
ASSIST, HEART MECHANICAL EXTRACORPOREAL
POIHL 08805 15 0044 Regulation ol ventilation and
pulmonary circulation Neurochemical interactions in
respiratory control (human, dogs, goats)
ROIHL 09609 11 Lung volume and breathing mechanics
during anesthesia (human)
POIHL 1034213 0028 The integrated function of
respiration and circulation Mediator release,
hemodynamics and respiratory function in anaphylaxis
(dogs)
ROIHL 13824 06 Defense mechanisms in pathogenesis of
emphysema (human, dogs)
POlHL-1498507 0009 Adaptation to hypoxia Influence
of chemosensitivity on control of breathing during sleep
(human, dogs)
•* POIHL 15194-07 0011 Pathophysiology ol
cardiopulmonary dysfunction Distribution of ventilation-
Oxygen effects on intrapulmonary shunting (human)
ROIHL 15668-06 Extracorporeal respiratory gas exchange -
A new approach (dogs)
P60HL-17292 04 0029 Vermont Lung Center Computer-
assisted preoperative evaluation (human)
** R01HL1735804 Ventilatory adiustments tor optimal
oxygenation (dogs, rats)
P50HL-19185-02 0004 Pulmonary SCOR -Neonatal
respiratory distress syndromes Fluid and protein transport
in fetal and newborn lung (sheep, rabbits)
ROlHL-19352-03 Respiratory heat and water loss in
neonates
RESPIRATORY ASSIST AND OXYGEN
ADMINISTRATION, AEROSOL THERAPY
POlHL-16137-05 0013 Alveolar biology Development and
pathology of surfactant-Formation of alveolar (rabbits,
sheep)
ROlHL-17776-04 Pulmonary mucus transport in
obstructive lung diseases (human)
•* R01HL19647-03 Therapeutic aerosols
** ROlHL-19700-03 Deposition of hygroscopic aerosols
(models)
** R01HL19704-03 Aerosol therapy (models, dogs, human)
** ROIHL- 197 15-02 Respiratory tract deposition of
hygroscopic aerosols (dogs, human)
"* ROlHL-1972203 Aerosol growth in the respiratory system
(models)
** ROlHL-20024-03 Therapeutic aerosols-Characteristics and
retention (human, dogs)
ROlHL-2010502 Deposition of hygroscopic aerosols in
bronchi (dogs, human, models)
RESPIRATORY ASSIST AND OXYGEN
ADMINISTRATION, ARTIFICIAL RESPIRATION
POlHL-10342-13 0008 The integrated function of
respiration and circulation - Respiratory mechanics and the
circulation (human, dogs)
ROlHL-13172-10 Post-trauma lung mechanics and fluid
exchange (human, dogs, monkeys)
** P50HL-17655-04 0003 Study of ischemic heart disease -
Cardiopulmonary resuscitation (human, dog)
ROlHL-2107602 Lung fluid, protein exchange after
hemorrhagic shock (sheep)
RESPIRATORY ASSIST AND OXYGEN
ADMINISTRATION, ELECTRONIC RESPIRATORY
STIMULATORS
** ROlHL-04651-19 Remote stimulation by radio-frequency
transmission (dogs, human)
RESPIRATORY ASSIST AND OXYGEN
ADMINISTRATION, FLUOROCARBON
POlHL-07896-15 0021 Environmental biomedical research
program - Liquid breathing and lung lavage (human)
** ROlHL-15520-06 Total blood replacement by fluorocarbons
and polyols (rats)
** ROlHL-16643-02 Fluorocarbon emulsions as artificial
blood (animals)
*• ROlHL-2284301 Pulmonary physiology in liquid ventilation
(lambs)
RESPIRATORY ASSIST AND OXYGEN
ADMINISTRATION, HYPERBARIC
OXYGENATION
M POlHL-07896-15 Environmental biomedical research
program
** POlHL-07896-15 0008 Environmental biomedical research
program - Otologic studies under hyperbaric conditions
(human, animals)
** PClHL-07896-15 0014 Environmental biomedical research
program - Mechanisms of respiration and circulation
(human, dogs)
** POlHL-07896-15 0019 Environmental biomedical research
program Hyperoxic myopia (human)
POlHL-07896-15 0021 Environmental biomedical research
program - Liquid breathing and lung lavage (human)
** POlHL-07896-15 0039 Environmental biomedical research
program - Development of resistance to lethal effects of
oxygen (rats)
'• POIHI 07896 15 0043 Environmental biomedical r»»«arth
program Effect of hyperbaric oxygen on the lung (human,
rabbits)
POlHt 0/896 15 0045 Envifonmenlal biomedical f«««iich
program Exiravascular lung water dynamics in pulmonary
oxygen toxicity (human, baboons)
•• POIHL 07896 15 0046 Environmental biomedical research
program Treatment ol radiation induced liliue in|ury by
hyperbaric oxygen (human)
•* POIHL 07896 lb 0049 Environmental biomedical research
program Effects of hyperbaric oxygen and pressure on
cerebral enzymes (rats)
■* P01HL07896 15 0059 Environmental biomedical research
program Hyperoxygenation at elevated atmospheric
pressure on myocardial blood flow (dogs)
•• P01HL08899 14 0008 Tolerance to respiratory gases in
health and disease Hypoxia in regards lo respiratory and
brain circulatory control (goats)
POlHL-08899 14 0010 Tolerance to respiratory gases in
health and disease High oxygen pressure in septic shock
(human)
POIHL 08899 14 0014 Tolerance to respiratory gases in
health and disease Cellular and renal responses to
hypercapnia and hypocapma (dogs)
** POIHL 08899 14 0024 Tolerance to respiratory gases in
health and disease Effects of oxygen pressures on
physiological control systems (human, dogs)
•* P50HL 15061 07 0002 Response of lung to in)ury
Oxidative metabolism, phospholipid synthesis, and response
to toxins (rats)
** P50HL 15061 07 0012 Response of lung to in)ury
Hyperbaric oxygen, carbon monoxide, and ozone or peroxide
toxicity (rats)
ROIHL 16855-03 Cavitation in biological systems
(microorganisms, animals)
ROlHL-1794403 Studies in lung preservation (dogs)
RESPIRATORY ASSIST AND OXYGEN
ADMINISTRATION, HYPEROXIA
SEE ALSO EYE DISORDERS, RETROLENTAL FIBROPUSIA
SEE ALSO RESPIRATORY ASSIST AND OXYGEN
ADMINISTRATION, HYPERBARIC OXYGENATION
POlHL-06370 17 0006 Cardiopulmonary and renal
pathology research center ■ Chemical basis of
ultrastructural changes in disease (rats)
M POlHL-0789615 Environmental biomedical research
program
" POlHL-07896-15 0032 Environmental biomedical research
program - Fluorometry study of brain exposed to hyperbaric
oxygen (dogs, cats)
** POlHL-07896-15 0039 Environmental biomedical research
program - Development of resistance to lethal effects of
oxygen (rats)
** P01HL07896-15 0045 Environmental biomedical research
program - Extravascular lung water dynamics in pulmonary
oxygen toxicity (human, baboons)
** POlHL-07896-15 0047 Environmental biomedical research
program - Pulmonary oxygen toxicity (chickens, rabbits)
** POlHL-07896-15 0049 Environmental biomedical research
program - Effects of hyperbaric oxygen and pressure on
cerebral enzymes (rats)
** POlHL-07896-15 0058 Environmental biomedical research
program - Lung synthesis of disaturated
phosphatidylcholine (rats, dogs, bats)
*• POlHL-07896-15 0059 Environmental biomedical research
program - Hyperoxygenation at elevated atmospheric
pressure on myocardial blood flow (dogs)
** POlHL-0789615 0063 Environmental biomedical research
program • Oxygen toxicity (baboons)
POlHL-08805-15 0039 Regulation of ventilation and
pulmonary circulation - Carotid body (cats)
M POlHL-08899-14 Tolerance to respiratory gases in health
and disease
** P01HL-08899-U 0007 Tolerance to respiratory gases in
health and disease - Effects of high oxygen pressures on
visual function (human, animals)
** POlHL-08899-14 0010 Tolerance to respiratory gases in
health and disease - High oxygen pressure in septic shock
(human)
** POlHL-08899-14 0012 Tolerance to respiratory gases in
health and disease - High oxygen for normal brain
metabolism and circulation in man
** P01HL08899-14 0017 Tolerance to respiratory gases in
health and disease - Pulmonary tolerance (human, dogs)
** POIHL-08899-14 0019 Tolerance to respiratory gases in
health and disease - High oxygen pressure upon carotid
chemoreceptor (cats)
** POlHL-08899 14 0020 Tolerance to respiratory gases in
health and disease - Oxygen tolerance (human, rats,
guinea pigs)
** POlHL-08899-14 0021 Tolerance to respiratory gases in
health and disease - Renal oxygen toxicity (dogs)
** POlHL-08899-14 0023 Tolerance to respiratory gases in
health and disease - Hypoxia and hyperoxia in respiratory
response in regards to PC02 (human)
** POlHL-08899-14 0025 Tolerance to respiratory gases in
health and disease - Effects of oxygen on cardiopulmonary
gas transport functions (dogs)
** POlHL-08899-14 0026 Tolerance to respiratory gases in
health and disease - Effects of oxygen on central nervous
system functions (rats, rabbits)
(contd)
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
RES
P01HL08899-14 0027 Tolerance to respiratory gases in
health and disease • Effects of high oxygen pressures on
ethanol metabolism (human)
POlHL-08899-14 0031 Tolerance to respiratory gases in
health and disease - Studies in exercise (human, dogs)
POlHL-08899-14 0032 Tolerance to respiratory gases in
health and disease - Effects of high oxygen pressures upon
respiratory control
POlHL-08899-14 0034
health and disease
Tolerance to respiratory gases in
Hyperoxygenation and respiratory
response to acid-base stimuli (human, dog)
" P01HL08899-I4 0035 Tolerance to respiratory gases in
health and disease - Simulation of the increased
metabolism of exercise (dogs)
*• P01HL08899-U 0042 Tolerance to respiratory gases in
health and disease ■ Definitions and extension of oxygen
tolerance in organ systems (animals)
" POlHL-08899-14 0043 Tolerance to respiratory gases in
health and disease - Oxygen effects upon CNS and sensory
functions (human)
** POlHL-08899-14 0044 Tolerance to respiratory gases in
health and disease Influence of high oxygen pressures on
cognition and performance
" P01HL08899-14 0045 Tolerance to respiratory gases in
health and disease - Studies in normal subjects
** POlHL-08899-14 0046 Tolerance to respiratory gases In
health and disease - Studies in senile elderly individuals
•* POIHL 08899-14 0047 Tolerance to respiratory gases in
health and disease - Oxygen effects on visual function
(human)
" POlHL-08899-14 0048 Tolerance to respiratory gases In
health and disease - Changes in human vision during
known tolerable exposures
** POlHL-08899-14 0049 Tolerance to respiratory gases in
health and disease - Dose-response measures of severe
oxygen toxicity (monkeys)
** POIHL 08899-14 0050 Tolerance to respiratory gases In
health and disease - Effects of high oxygen pressures on
visual pigment functions (monkeys)
** POlHL-08899-14 0051 Tolerance to respiratory gases In
health and disease - Oxygen effects upon isolated retinal
metabolism (rabbits, monkeys)
■• POlHL-08899-14 0052 Tolerance to respiratory gases In
health and disease - Oxygen effects on auditory and
vestibular function (human, guinea pigs)
■* POlHL-08899-14 0054 Tolerance to respiratory gases In
health and disease - Glucose transport across choroid
plexus (dogs)
■• POlHL-0889914 0055 Tolerance to respiratory gases in
health and disease - Oxygen effects on organ functions-
Extension of tolerance
■* POlHL-08899-14 0056 Tolerance to respiratory gases In
health and disease - Extension of pulmonary oxygen
tolerance at increased pressures (animals)
* POlHL-0889914 0057 Tolerance to respiratory gases In
health and disease - Studies of intermittent exposure in
man
* POlHL-08899-14 0061
health and disease
functions (rats, dogs)
* POlHL-08899-14 0062 Tolerance to respiratory gases in
health and disease - Influence of oxygen at high pressure
upon oxidation (rats)
POlHL-08899-14 0066 Tolerance to respiratory gases in
health and disease - Neurophysiological effects of Inert
gases in man
Tolerance to respiratory gases In
Inert gas influences upon visual
Tolerance to respiratory gases In
Hepatic oxygenation and secretory
Tolerance to respiratory gases in
Decompression by applications of
* POlHL-08899-14 0067
health and disease -
function in man
POlHL-08899-14 0089
health and disease
optimal control theory
ROlHL-12530-10 Emphysema- Respiratory function in
disease (human, dogs, rats)
ROIHL 13233-08 Cardiorespiratory control in exercise
(human)
ROlHL-14663-07 Pulmonary oxygen toxicity in newborn
lung (human, mice)
ROlHL-14717-06 Hemodynamics and heart structure-
Ventricular overload (dogs)
P50HL-1506I-07 0002 Response of lung to injury -
Oxidative metabolism, phospholipid synthesis, and response
to toxins (rats)
P50HL-15061-07 0004 Response of lung to injury -
Biochemical abnormalities in connective tissues (rats)
' P50HL 15061-07 0012 Response of lung to injury -
Hyperbaric oxygen, carbon monoxide, and ozone or peroxide
toxicity (rats)
POlHL-15832-06 0001 Chemical-structural predispositions
to lung injury ■ Chemical composition of lung connective
tissue proteins (human, animals)
POlHL-15832-06 0007 Chemical-structural predispositions
to lung injury - Inactivatlon of vasoactive agents by the
lung (human, rats. cats, dogs)
POlHL-16137-05 Alveolar biology
POlHL-16137-05 0004 Alveolar biology - Subcellular
processes and controls in the surfactant system (animals)
POlHL-16748-05 0004 Cellular and immunological basis
of pulmonary diseases Cellular and immunological
processes in pulmonary defense systems
ROlHL-16828-04 Gradient and transport of oxygen in
tissue and organs (mammals)
Oxygen toxicity In the red cell (human)
Biochemistry of lung connective tissue
458
ROlHL-17314-04 Effects of anesthesia and loading on
respiration (human, cats)
ROlHL-17719-03 Lung Injury, substrate utilization, oxygen
toxicity (rats, rabbits, dogs)
ROIHL 17826-04 Oxygen delivery to tissue (rat. dog)
P01HL-18708-03 0010 Oxygen, energy and contractility In
cardiac tissue - Tissue oxygen utilization (rats, dogs)
ROlHL-19010-03 Metabolism and cell biology of lung
surfactant system (rabbits, sheep)
ROlHL-1919503 Hormonal regulation of lung function
(rats)
** R01HL19532-01
ROlHL-19668-03
(rats)
POlHL-19717-02 0004 Response of the lung to injury -
Regulatory and physical-chemical properties of lung lysyl
oxidase (animals)
** POlHL-19717-02 0025 Response of the lung to Injury ■
Role of oxygen in regulation of lung growth and
development (rats)
ROlHL-19779-03 Biochemical basis of oxygen damage to
lung cells (guinea pigs, rats)
ROlHL-20352-02 Defenses of lung cells against oxygen
toxicity (human, animals)
ROlHL-20566-02 Lactate metabolism in the lung (rats)
ROlHL-21115-01 Prevention of 02 toxicity with superoxide
dismutase (rats)
ROlHL-22259-01 Modification of susceptibility to oxygen
poisoning (rats)
R01HL-23209-01 Autonomic receptors of the pulmonary
vasculature (mammals)
ROlHL-23211-01 Active normoxic pulmonary vasodilatation
(rat. dog. sheep)
RESPIRATORY ASSIST AND OXYGEN
ADMINISTRATION, HYPERVENTILATION
PASSIVE
POlHL-14388-07 0185 Regulation of the circulation in
pathological states Reflex control of venous tone (human,
rabbits, dogs)
RESPIRATORY ASSIST AND OXYGEN
ADMINISTRATION, NEGATIVE PRESSURE
BREATHING
POlHL-144 14-07 0007 Environmental Influences on
cardiorespiratory and cellular functions - Neural control of
respiration (human, cats)
RESPIRATORY ASSIST AND OXYGEN
ADMINISTRATION, OXYGEN INHALATION
THERAPY
ROlHL-03941-18 Uterine blood flow and changes in
pregnancy (sheep)
POlHL-08899-14 0056 Tolerance to respiratory gases in
health and disease - Extension of pulmonary oxygen
tolerance at Increased pressures (animals)
ROlHL-1 1907-08 Mechanisms of physiological responses
to exercise (human, dogs)
R01HL12564-09 Control of respiration and blood gases
(human, dog)
ROlHL-15430-05 Cardiopulmonary adaptation of newborns
to altitude (human)
P50HL-17682-04 0007 Study of ischemic heart disease -
Mechanisms of hypoxemia in myocardial Infarction (human)
P50HL-19185-02 0011 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Complications and
sequelae of neonatal respiratory distress (human)
ROlHL-206 12-02 Chronic animal model of pulmonary
vascular Injury (dogs)
R23HL-20968-02 Respiratory failure -Control and muscle
dysfunction (human)
** ROlHL-22622-01 Sleep apnea and desaturation-
mechanisms and incidence (human)
** NOlHR-62942-04 Nocturnal oxygen therapy in chronic
hypoxic lung disease (humam)
NOlHR-62943-05 Nocturnal oxygen therapy in chronic
hypoxic lung disease (human)
** NOlHR-62944-04 Nocturnal oxygen therapy in chronic
hypoxic lung disease (human)
** NOlHR-62945-04 Nocturnal oxygen therapy In chronic
hypoxic lung disease (human)
** NOlHR-62946-04 Nocturnal oxygen therapy in chronic
hypoxic lung disease (human)
NOlHR-62947-04 Nocturnal oxygen therapy In chronic
hypoxic lung disease (human)
RESPIRATORY ASSIST AND OXYGEN
ADMINISTRATION, POSITIVE PRESSURE
BREATHING
Newborn lung center for hyaline
■ Pulmonary status of children who had
P50HL 14214-07 0012
membrane disease
HMD as infants
P50HL-142 14-07 0030
membrane disease
Newborn lung center for hyaline
Effects of ductal patency-Impedance
cardiography and echocardiography (human)
P01HL-I44 14-07 0007 Environmental influences on
cardiorespiratory and cellular functions - Neural control of
respiration (human, cats)
POlHL-144 14-07 9002 Environmental influences on
cardiorespiratory and cellular functions - Core -Computer
facility
RES
POlHL-14580-07 0003 Program project in respiratory
mechanics - Chest wall mechanics and respiratory control
(human, dogs)
ROlHL-15526-05 Respiratory mechanics In children
** P60HL-17292-04 0009 Vermont Lung Center - Controlled
clinical trials on a clinical core unit (human)
ROlHL-17719-03 Lung Injury, substrate utilization, oxygen
toxicity (rats, rabbits, dogs)
POlHL-17731-04 0006 Physiological basis of pulmonary
disease - Ventllatlon-perfuslon ratios (human, dogs)
P50HL-19155-02 0001 Pathophysiology of pulmonary
edema - Pulmonary edema study unit (human, dog)
P50HL 19185-02 0007 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Sodium bicarbonate and
albumin In resuscitation of preterm Infants (human)
" P50HL-19185-02 0009 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Nasal continuous positive
ainway pressure In hyaline membrane disease (human)
P5aHL-19185-02 0011 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Complications and
sequelae of neonatal respiratory distress (human)
" P50HL-19187-02 0010 Pediatric pulmonary SCOR -Hyaline
membrane disease Treatment, outcome of HMD-
Continuous positive airway pressure (human, monkey)
ROIHL 19449 03 Gas exchange In acute respiratory failure
ROIHL-20690-02 Pulmonary hemodynamics In lung edema
during PEEP (dogs)
R23HL-21405-01 Respiratory muscles In regulation of
Infant breathing (human)
** NOlHR-72901-02 Study of intermittent positive pressure
breathing (data center)
■* NOlHR-72902-04 Study of intermittent positive pressure
breathing
■* NOlHR-72903-05
breathing
'* NOlHR-72904-03
breathing
■* NOlHR-72905-03
breathing
* NOlHR-72906-03
breathing
Study of Intermittent positive pressure
Study of intermittent positive pressure
Study of intermittent positive pressure
Study of Intermittent positive pressure
RESPIRATORY ASSIST AND OXYGEN
ADMINISTRATION, PULMONARY LAVAGE
POlHL-07896-15 0021 Environmental biomedical research
program - Liquid breathing and lung lavage (human)
** ROlHL-13885-08 0005 Cystic fibrosis and pulmonary
disease - Evaluation of lobar pulmonary lavage (human)
ROlHL-13885-08 9003 Cystic fibrosis and pulmonary
disease - Fiberoptic bronchoscopy core facility (human.
dogs, sheep)
P50HL-14212-07 0004 Correlated studies of pulmonary
fibrosis - Collagen metabolism In lung tissue and lung
cells (human, animal)
P50HL 14212-07 0006 Correlated studies of pulmonary
fibrosis Alveolar macrophage physiology (human, rodents.
rabbits)
P50HL-14212-07 0007 Correlated studies of pulmonary
fibrosis - Protein metabolism In alveolar macrophages
(rabbits, guinea pigs, human)
** P50HL-14212-07 0014 Correlated studies of pulmonary
fibrosis - Pulmonary lavage cells, secretions In diffuse
intersititlal lung disease (human)
ROlHL-15013-07 Lung oxidative metabolism and energy
production (rodents, rabbits)
ROlHL-16154-05 Membrane lung perfusion for acute
respiratory failure (sheep, baboons)
** POlHL-16748-05 0006 Cellular and immunological basis
of pulmonary diseases - Sarcoldosis-Studies with bronchial
lavage (human)
** POlHL-17417-05 0003 Experimental lung transplantation
Methods for detecting lung allograft rejection (dogs)
ROlHL-22843-01 Pulmonary physiology in liquid ventilation
(lambs)
RESPIRATORY ASSIST AND OXYGEN
ADMINISTRATION, RESPIRATORS
P50HL-14214-07 0012 Newborn lung center for hyaline
membrane disease - Pulmonary status of children who had
HMD as Infants
POlHL-17813-04 0006
of blood and tissue
^Excludes routine methodology OR covers only general projects which preclude indexing
Oriented significantly to above subject.
at the specific level.
M Grant has subprojects describing specific research aspects
See Appendix (or investigator's name and grant number-
Lung disease and the oxygenation
Assessment of respiratory muscle
contractile force (human, dogs)
R23HL-20968-02 Respiratory failure -Control and muscle
dysfunction (human)
ROlHL-22022-01 Respiratory muscle dysfunction in
respiratory failure (human)
RESPIRATORY CARE UNITS
SEE HOSPITALS. INTENSIVE CARE UNITS, RESPIRATORY
RESPIRATORY CENTER
SEE BRAIN, RESPIRATORY CENTER
RESPIRATORY CENTER DYSFUNCTION
HYPOVENTILATION
SEE RESPIRATORY FUNCTION, HYPOVENTILATION,
RESPIRATORY CENTER DYSFUNCTION
RESPIRATORY CIRCULATION
ROlHL-06143-18 Response of the totally denervated heart
to exercise (dogs)
(contd)
RES
POIHI 08899 14 0008 Iolei«nc« to tespiritory |<»s In
health and disease Hypoxia in regards to lesplfatory end
brain ciiculatoty control (goats)
*• POIHI 08899 \4 0024 Tolerance to respitatoiy gases in
health and disease Eltects ol oxygen pressures on
physiological control systems (human, dogs)
ROIHL 173b8 04 Ventilatoiy adiustments tor optimal
oxygenation (dogs, rats)
•* ROIHI 2194801 Capillary, tissue volume and lymph How
in lung edema (sheep, cattle)
RESPIRATORY CIRCULATION, BRONCHIAL
CIRCULATION
P01HL06285 18 014S CardiovasculairespliatoiV
physiology and biochemistrv Pulmonary, pleural and
systemic microcirculation (animals)
ROIHL 167140S Endothelial cell communication in
homeostasis (human, mammals)
POIHL 17417 05 0006 Experimental lung transplantation
Bronchial anastomotic problems and increases donor lung
availability (dog)
** ROIHL 2292801 Systematic study of bronchial Circulation
(sheep)
RESPIRATORY CIRCULATION, PULMONARY
ARTERY
•* POIHL 0631217 0048 Surgical cardiology ■ Use of an
adjustable pulmonary artery band (dogs)
" POlHL-0631217 0049 Surgical cardiology - Long-term
pulmonary vascular resistance (human)
** POlHL-0637017 0016 Cardiopulmonary and renal
pathology research center Endocarditis witli pulmonary
artery catheters (dogs)
R01HL08359 14 Morphopharmacology of vascular
adrenergic transmission (rabbits, rats)
P01HL08805-15 0049 Regulation of ventilation and
pulmonary circulation Pulmonary hypertension produced
by Dirofilaria immitis in the dog
POlHL-1131012 0075 Mechanisms of cardiovascular
disease - Bipolar atrial electrograms from Bachmann's
bundle (dogs)
R01HL14645-07 Blood tlovi measurement by ultrasonic
catheter tip methods (human, dogs)
*• ROlHL-1807004 Regulation of intrapulmonary airways
and vessels (human, animals)
ROlHL-18371-03 Pulmonary hypertension and ventilation
pathophysiology (dogs)
ROlHL-20087-02 Developmental processes in pulmonary
hypertension (rats)
ROlHL-20219-02 Cryopreservation of the isolated heart
(rats)
ROlHL-2042903 Study of effects of diabetes reactivity
(miniature pigs, rats)
** POlHL-2058101 0004 Vascular ncuroeffector
mechanisms m health and disease ■ Neuroeffector
characteristics of mesenteric and pulmonary blood vessels
(rabbits)
** ROlHL-22177-02 Mechanisms of control of pulmonary
smooth muscle (dogs)
** ROlHL-23205-01 Contraction of pulmonary vascular
smooth muscle (cat)
ROlHL-23224-01
muscle (rat, cat)
ROlHL-23232-01
precursor cells
Pulmonary artery intermediate filament
Hypoxia and pulmonary vascular smooth
Effect of hypoxia on PVSM and its
ROlHL-23233-01
structure (cattle)
ROlHL-2323901
Functional characteristics of pulmonary
vascular smooth muscle (dogs)
ROlHL-23245-01 Adrenergic receptors in pulmonary
vascular muscle (human, animal)
ROlHL-23249-01 Actinmyosin interaction in pulmonary
smooth muscle (cattle)
** ROlHL-23542-01 Pulmonary vascular smooth muscle cell
dynamics (rat, rabbit)
NOlHR-62920-02 Noninvasive diagnosis of pulmonary
hypertension (dog. human)
RESPIRATORY CIRCULATION, PULMONARY
CIRCULATION
** ROlHL-03180-21 Relation of lymphatics to
cardiopulmonary function (dogs)
POlHL-04664-18 0016 Cardiovascular and lung dynamics
- Computerized roentgenographic determination of total
lung capacity
** ROlHL-05883-18 0006 Reflex control of resistance and
capacitance vessels ■ Cardiopulmonary vagal afferents in
the conscious dog
POlHL-06285-18 0127 Cardiovascular-respiratory
physiology and biochemistry - Experimental congenital
cardiac lesions in fetal lambs
** POlHL-06285-18 0128 Cardiovascular-respiratory
physiology and biochemistry - Pulmonary circulation in fetal
lambs in utero
** POlHL-06285-18 0129 Cardiovascular-respiratory
physiology and biochemistry - Pulmonary microcirculation in
the fetus and neonate (lambs)
POlHL-06285-18 0136 Cardiovascular-respiratory
physiology and biochemistry - Fetal microcirculation in
utero (rabbits, lambs)
** POlHL-0628518 0145 Cardiovascular-respiratory
physiology and biochemistry - Pulmonary, pleural and
systemic microcirculation (animals)
459
P01HL-06285 18 0181 Cardiovascular respiratory
physiology and biochemistry Regulation of respiration
Role of vagus nerve (dogs)
' POIHI 06296 18 0002 Cardiovascular and pulmonary
adaptation to stress Respiratory muscle blood flow,
mechanics and metabolism (human, dog)
POIHL 06314 17 0047 Immunologic mechanisms in
cardiovascular disease Role of intravascular coagulation
(human, animals)
• P01HL0683b 17 0051 Cardiovascular disease
Cardiopulmonary volume in hypertension (human)
POIHL 06835 17 0053 Cardiovascular disease
Vasodilating drugs (human)
P01HL07896 15 0014 Environmental biomedical research
program Mechanisms ol respiration and circulation
(human, dogs)
• P01HL08682 15 0038 Regulation of the cardiovascular
system Control of pulmonary circulation (dogs)
ROIHL 08696 15 0020 Orthotopic heart transplantation -
Complete cardiopulmonary transplantation (dogs)
POIHL 08805 15 0025 Regulation of ventilation and
pulmonary circulation Pulmonary edema (rabbits)
P01HL08805 15 0049 Regulation ol ventilation and
pulmonary circulation ■ Pulmonary hypertension produced
by Dirofilaria immitis in the dog
POIHL 08899 14 0080 Tolerance to respiratory gases in
health and disease Dynamic quantitation of continuous
isobaric gas embolization
'* ROIHL 1000913 Regional lung function in man
«l POlHL-10342 13 The integrated function of respiration
and circulation
•* POIHL 10342-13 0006 The integrated (unction of
respiration and circulation Lung inflation effects on
pulmonary vasculature and interstitial space (dogs)
POlHL-10342-13 0008 The integrated function of
respiration and circulation - Respiratory mechanics and the
circulation (human, dogs)
** POlHL-10342-13 0024 The integrated function of
respiration and circulation - Cytochrome P450 and
physiological response to hypoxia (rats)
** POlHL-10342-13 0025 The integrated function of
respiration and circulation - Pulmonary gas exchange and
metabolism (human, dogs, sheep)
POlHL-10436-13 0005 A multidisciplinary study of
congenital heart disease - Pulmonary physiology in
congenital heart disease (human)
** R01HL10622-12 Volumes and compliance of pulmonary
circulation (human, dogs)
" ROlHL-1083409 Fetal and neonatal pulmonary circulation
(goats)
" ROIHLI 11 52-12 Vascular physiology (human, cats, dogs)
POlHL-11310-12 0060 Mechanisms of cardiovascular
disease Effect of left atrium on the circulation-Simulation
POIHLI 1678-11 0009 Cardiovascular dynamics and their
control - Control of respiration (cat, human)
** POlHL-11678-11 0036 Cardiovascular dynamics and their
control - Pulmonary capillary dynamics and edema (dogs)
ROlHL-11802-10 Cardiovascular surgical research (dogs,
sheep, swine, cats, monkeys)
ROIHL 1190708 Mechanisms of physiological responses
to exercise (human, dogs)
** ROlHL-11919-08 Pulmonary circulation in surgical heart
disease (human, dogs)
** ROlHL-12530-10 Emphysema -Respiratory function in
disease (human, dogs, rats)
M ROlHL-12879-09 Pulmonary transport and metabolism in
vivo
ROlHL-131 72-10 Post-trauma lung mechanics and fluid
exchange (human, dogs, monkeys)
ROlHL-133 15-08 Disposition of vasoactive hormones in
mammalian lung (rats, rabbits, human)
** R01HL-13901-08 Ontogeny, ultrastructure, function in
lymphatic system (birds, fish, mammals)
P50HL-141 53-07 0017 Johns Hopkins Lung Center-
Chronic diseases of airways - Collateral ventilation and
pulmonary interdependence (pig. dog. human)
** P50HL-14187-07 0015 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses -
Pathophysiologic responses of pulmonary capillary bed
(dog. human)
** P50HL-142 14-07 0025 Newborn lung center for hyaline
membrane disease - Pulmonary vascular permeability and
lung water-Hyaline membrane disease (sheep)
P50HL-142 14-07 0026 Newborn lung center for hyaline
membrane disease - Hemodynamic studies of HMD-
Prostaglandins production and blockers (lambs)
P50HL-142 18-07 0017 Pulmonary SCOR -Newborn lung
center - Transvascular fluid exchange, vasoactive mediators
in RDS (sheep, cat)
POlHL-144 14-07 0007 Environmental influences on
cardiorespiratory and cellular functions - Neural control of
respiration (human, cats)
POlHL-14414-07 0015 Environmental influences on
cardiorespiratory and cellular functions - Control of the
cardiovascular system (dogs)
** ROlHL-14456-07 Lung metabolism-Enzymes in the
pulmonary circulation (human, animals)
ROlHL-14529-07 Systems analysis of baroreflex (dogs)
ROlHL-14967-06 Chemoreceptor function in dynamic
ventilatory control (human, dogs)
M POlHL-14985-07 Adaptation to hypoxia
RIS
POIHI 1498'j 0/ 0005 Adaptation to hypoxia Conlrot
mechanisms in the pulmonary microcirculation (ininnlil
POIHL 14985 07 0007 Adaptation to hypoxia Control of
pulmonary circulation, histamine and the sympathelict
(animals)
' POIHI 14985 07 0010 Adaptation to hypoxia Pulmonary
mast cell (animals)
• POIHL 14985 07 0011 Adaptation to hypoxia
Prostaglandins in the control of the pulmonary circulation
(animals)
POIHL 14985 07 0012 Adaptation to hypoxia Direct
effect of hypoxia on pulmonary vascular smooth muscio
(rats, dogs)
POIHL 14985 07 0014 Adaptation to hypoxia High
altitude pulmonary edema (human, rats, dogs)
• POIHL 14985 07 0015 Adaptation to hypoxia Pregnanej
at high altitude (human, animals)
I POIHL 15194 07 Pathophysiology of cardiopulmonary
dysfunction
POIHL 15194 07 0009 Pathophysiology of
cardiopulmonary dysfunction Kinetics of gas eichanu-
Oiffusion and erythrocytes reaction rates (human, dogs)
* POIHL 15194 07 0011 Pathophysiology of
cardiopulmonary dysfunction Distribution of venlilalion-
Oxygen effects on intrapulmonary shunting (human)
POIHL 15194 07 0022 Pathophysiology of
cardiopulmonary dysfunction Kinetics of gas exchange-
Pulmonary carbon dioxide exchange (dogs)
* ROIHL 15430-05 Cardiopulmonary adaptation of newborns
to altitude (human)
ROIHL 1552605 Respiratory mechanics in children
'* ROIHL 15580-06 Humoral control of pulmonary and
systemic circulation (animals)
ROIHL 15593-05 Prolonged extracorporeal cardiopulmonity
support (rats, sheep, rabbits)
*• R01HL15694 06 Pulmonary factors in circulatory
regulation
POlHL-15832-06 0005 Chemical-structural predispositton*
to lung injury Pulmonary structure and stress-strain
relationships (rats)
POlHL-1583206 0007 Chemical-structural predispositions
to lung injury Inactivation of vasoactive agents by the
lung (human, rats, cats, dogs)
** ROlHL-16154-05 Membrane lung perfusion for acute
respiratory failure (sheep, baboons)
ROlHL-16714-05 Endothelial cell communication in
homeostasis (human, mammals)
ROlHL-16784-03 Lung tissue and water volume (human.
dogs)
** ROlHL-16916-04 0001 The role of albumins in lung water
accumulation - Capillary permeability (dogs, human)
ROIHL- 169 1604 0002 The role of albumins in lung water
accumulation - Lung water balance-forces, models and
albumin concentrations (rabbits, dogs)
" ROlHL-1735504 Pulmonary vascular adjustments in
circulatory collapse (dogs, rats)
POlHL-17417-05 0005 Experimental lung transplantation
- Lung transplantation in bilateral emphysema (dogs)
ROlHL-17479-04 Blood storage -The production of
cardiotoxic material (dogs, human, swine)
P50HL-17655-04 0003 Study of ischemic heart disease •
Cardiopulmonary resuscitation (human, dog)
P50HL-17665-04 0027 Study of ischemic heart disease -
Positron imaging of regional myocardial perfusion (human,
dog)
P50HL- 17682-04 0007 Study of ischemic heart disease •
Mechanisms of hypoxemia in myocardial infarction (human)
" R01HL17711-05 Mechanism of hypoxic regulation of lun|
circulation (rats, cats, guinea pigs)
M POlHL-17731-04 Physiological basis of pulmonary disease
" POlHL-1773104 0001 Physiological basis of pulmonary
disease - Mechanisms of blood flow and ventilation (dogs)
** POlHL-17731-04 0002 Physiological basis of pulmonary
disease - Biomechanics of the lung (frogs, cats)
** POlHL-17731-04 0003 Physiological basis of pulmonary
disease - Comparative physiology (vertebrates)
** POlHL-1773104 0007 Physiological basis of pulmonary
disease - Theoretical gas exchange
** POlHL-17731-04 0011 Physiological basis of pulmonary
disease - Morphometric studies of the lung -Core
ROlHL-l 7768-04 Development of collateral ventilation
(dogs, fish, horses)
POlHL-17812-04 0007 Thrombosis and plasma proteins -
Blood components-Response to endotoxin (dogs, baboons)
M POIHL- 178 13-04 Lung disease and the oxygenation of
blood and tissue
** POlHL-17813-04 0001 Lung disease and the oxygenation
of blood and tissue - Diffuse interstitial lung disease-
Pathophysiology (human, dogs)
ROlHL-18028-03 Absorption of nonvolatile compounds
from the lung
ROlHL-18070-04 Regulation of intrapulmonary airways
and vessels (human, animals)
R01HL18084-03 Artificial heart and related problems
(calves)
" ROlHL-18371-03 Pulmonary hypertension and ventilation
pathophysiology (dogs)
ROIHL 18606-04 Pathogenesis and measurement of
pulmonary edema (human, rabbits, dogs)
** ROlHL-18630-03 Pulmonary hemodynamics in atelectasis
and hypoxia (dogs)
(contd)
•Excludes routine methodology OR covers only general proiects which preclude
"Oriented significantly to at»ve subject
indexing at the specific level.
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
RES
Prostaglandin precursors and vascular
Post-traumatic pulmonary insufficiency
ROlHL-18718-04
reactivity (dogs)
ROlHL-18762-03
(dogs)
ROlHL-18952-03 Metabolism in perfused fetal and
neviborn rabbit lungs
ROlHL-19056-03 Blood triglycerides and lipoprotein lipase
in the lung (rats)
P50HL-19153-02 SCOR -Pulmonary edemas-Eitology,
pathogenesis
P50HL-19153-02 0001 SCOR -Pulmonary edemas-Eitology,
pathogenesis - Prostaglandins and the lung circulation
(sheep)
P50HL-19153-02 0002 SCOR -Pulmonary edemas-Eitology.
pathogenesis - Lung fluid dynamics-Classical mediators
and their inhibitors (sheep)
P50HL-19153-02 0003 SCOR-Pulmonaiy edemas-Eitology,
pathogenesis - Possible inhibitors of mediator release and
pulmonary vascular response (sheep)
P50HL-19153-02 0004 SCOR -Pulmonary edemas-Eitology,
pathogenesis - Physical mechanisms in lung transvascular
transport-Math models (sheep)
P50HL-19153-02 0005 SCOR-Pulmonary edemas-Eitology,
pathogenesis - Lung vascular permeability measured by
indicator dilution methods (sheep)
P50HL-19153-02 0006 SCOR-Pulmonary edemas-Eitology.
pathogenesis - Pulmonary vascular abnormalities in human
lung diseases
P50HL-19153-02 0007 SCOR-Pulmonary edemas-Eitology,
pathogenesis - Core-Experimental laboratories and support
facilities
P50HL-19155-02 0001 Pathophysiology of pulmonary
edema ■ Pulmonary edema study unit (human, dog)
P50HL-191 55-02 0005 Pathophysiology of pulmonary
edema - Protein exchange sites and lymph protein
concentration in lung (mice, sheep)
P50HL-19156-02 0002 Pulmonary SCOR-Chronic diseases
of airways - Early detection of emphysema and chronic
airway obstruction (human, dog)
P50HL-19185-02 0004 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Fluid and protein transport
in fetal and neviborn lung (sheep, rabbits)
P50HL-19185-02 0009 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Nasal continuous positive
airway pressure in hyaline membrane disease (human)
P50HL-19185-02 0011 Pulmonary SCOR-Neonatal
respiratory distress syndromes ■ Complications and
sequelae of neonatal respiratory distress (human)
P50HL-19187-02 0001 Pediatric pulmonary SCOR-Hyaline
membrane disease - Hyaline membrane disease -Changes
in lung mechanics and gas exchange (monkeys)
ROlHL-19225-02 Types and mechanims of pulmonary
hypertension
Types and mechanims of
Structural changes (human.
ROlHL-19225-02 0001
pulmonary hypertension
animals)
ROlHL-19225-02 0002
pulmonary hypertension
(pigs)
R01HL19225-02 0003
pulmonary hypertension
and rats
ROlHL-19225-02 0004
pulmonary hypertension
Types and mechanims of
■ Effect of aorto-pulmonary shunt
Types and mechanims of
• Cardiopulmonary function in pigs
Types and mechanims of
• Structural changes in human
pulmonary circulation (human, animals)
• ROlHL-19298-03 Pulmonary hemodynamics (dogs, cats)
R01HL19733-03 Absorption of antigen through inflamed
lungs (rabbits)
POlHL-19737-02 0004 Cellular and molecular aspects of
respiratory physiology - Rapid reactions and erythrocyte
exchanges of blood during respiratory transport
POlHL-19737-02 0010 Cellular and molecular aspects of
respiratory physiology - Effects of pulsatile flow and volume
on capillary exchanges (dogs, rats)
ROlHL-20344-02 Regulation of protein turnover in lung
tissue (rats)
ROlHL-20366-03 Protein turnover and amino acid
transport by lung (rats)
ROlHL-20429-03 Study of effects of diabetes reactivity
(miniature pigs, rats)
ROlHL-20548-02 Innervation of the lung (rats, monkeys)
ROlHL-2061202 Chronic animal model of pulmonary
vascular injury (dogs)
ROlHL-20652-01 Sites of leakage in pulmonary edema
(dogs)
R01HL-20690-02 Pulmonary hemodynamics in lung edema
during PEEP (dogs)
ROlHL-207 19-02 Cold induced pulmonary hypertension
(cattle)
ROlHL-20989-01 Pathophysiology of bronchial asthma
(sheep, dogs)
POlHL-20994-02 0001 Dynamics of neutrophil elastase in
the lung - Dynamics of neutrophil elastase in normal
animals (dogs, rabbits)
POlHL-20994-02 0002 Dynamics of neutrophil elastase in
the lung - Neutrophil and neutrophilic elastase in human
lungs
ROlHL-21076-02 Lung fluid, protein exchange after
hemorrhagic shock (sheep)
R23HL-2 1168-01 Hypoxemic respiratory failure- Physiologic
evaluation (human, dogs)
460
ROlHL-21452-02 Pulmonary capillary filtration in
myocardial ishemia (dogs)
ROlHL-21568-02 Cell biology of the alveolar-capillary unit
(animals)
POlHL-21584-02 0003 Respiratory mechanics in normal
and abnormal states - Effects of anesthesia on ventilation
and respiratory mechanics in man
R23HL-21853-01 Lung metabolism and alveolo-capillary
permeability (rats)
ROlHL-21893-01
(human)
R23HL-21943-01
RES
ROlHL-2011002 Microwave methods of lung water
measurement (dogs, phantom models)
Blood volume distribution in hypertension
Capillary morphology in pulmonary
edema (dogs)
ROlHL-22077-01 Vasoactive amine disposition in cultured
endothelium (rabbits)
ROlHL-22223-01 The cardiopulmonary junction (dogs,
models)
** ROlHL-22244-01 Cardiopulmonary bypass and the
vascular endothelium (dogs)
ROlHL-22326-01 Noninvasive measurement of cardiac
output (dogs)
R23HL-22346-01 Hematological injury and pulmonary
dysfunction (human, mammals)
** ROIHL 22520-01 Pulmonary vascular response to group B
Streptococci (human, mammals)
** ROlHL-22641-01 Ventilation, perfusion, and systemic
arterial reflexes (dogs)
** ROlHL-229 11-01 Mechanism of clearance of lung edema
fluid (dogs)
R23HL-22933-01 Transvascular fluid and protein exchange
in the lung (sheep)
ROlHL-23015-01 Mechanisms of hypo-oncotic pulmonary
edema (human, dogs)
ROlHL-23209-01 Autonomic receptors of the pulmonary
vasculature (mammals)
** ROIHL-232 10-01 Biology of normal and hypertrophied
pulmonary vessels (cat, human)
ROlHL-232 11-01 Active normoxic pulmonary vasodilatation
(rat, dog, sheep)
** ROlHL-23232-01 Effect of hypoxia on PVSM and its
precursor cells
** ROlHL-23239-01 Functional characteristics of pulmonary
vascular smooth muscle (dogs)
" ROlHL-23240-01 Pulmonary vascular muscle metabolism
and contractility (rats, cattle)
ROlHL-23245-01 Adrenergic receptors in pulmonary
vascular muscle (human, animal)
NOlHV-12060-18 Tissue cultured endothelium for vascular
prosthetic devices (human, animals)
RESPIRATORY CIRCULATION, PULMONARY
VEINS
ROlHL-15694-06 Pulmonary factors in circulatory
regulation
ROlHL-221 77-02 Mechanisms of control of pulmonary
smooth muscle (dogs)
ROlHL-23245-01 Adrenergic receptors in pulmonary
vascular muscle (human, animal)
RESPIRATORY CIRCULATORY DISORDERS
SEE ALSO CONGENITAL ABNORMALITIES, RESPIRATORY
DISTRESS SYNDROME
SEE ALSO DISEASES, SYNDROMES NOT LISTED ELSEWHERE,
GOODPASTURE'S SYNDROME
SEE ALSO RESPIRATORY DISORDERS (GENERAL)
SEE ALSO RESPIRATORY DISORDERS, PULMONARY EDEMA
ROlHL-1 1802-10 Cardiovascular surgical research (dogs,
sheep, swine, cats, monkeys)
ROlHL-1 19 19-08 Pulmonary circulation in surgical heart
disease (human, dogs)
M P50HL-14187-07 Pulmonary SCOR-Chemical mediators in
pulmonary vascular responses
" P50HL-14187-07 0012 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses - Vasoactive
mediators in pulmonary disease (human, animal)
** P50HL-14187-07 0014 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses ■ Metabolism
and actions of vasoactive peptides in lung (human,
mammals)
** P50HL-14187-07 0016 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses - Core
pathology service (dogs, rabbits, human)
P50HL-142 18-07 0017 Pulmonary SCOR-Newborn lung
center - Transvascular fluid exchange, vasoactive mediators
in ROS (sheep, cat)
M POlHL-14985-07 Adaptation to hypoxia
** POlHL-14985-07 0010 Adaptation to hypoxia ■ Pulmonary
mast cell (animals)
ROlHL-17437-03 'Perfusion lung'-Role of traumatized
leukocytes (dogs, human)
** ROlHL-177 11-05 Mechanism of hypoxic regulation of lung
circulation (rats, cats, guinea pigs)
" ROlHL-17800-04 Pulmonary reflexes -Central pathways
(cats, dogs, rabbits)
POlHL-17813-04 0002 Lung disease and the oxygenation
of blood and tissue - Diffuse interstitial lung disease-
Ultrastructural abnormalities (human)
P50HL-I91 55-02 0001 Pathophysiology of pulmonary
edema - Pulmonary edema study unit (human, dog)
ROlHL-19721-03 Lung inflammation-Lysosomal proteases
and liposomes (human, rabbits)
ROlHL-19725-03 Complement induced pulmonary injury
(dogs, rabbits, sheep)
ROlHL-20675-02
ROlHL-20878-02
rabbits)
ROlHL-2232701
skin (swine)
Alveolar macrophage function in man
Cellular aspects of lung injury (rats.
Transport of arterial blood gases through
•Excludes routine methodoloB OR covers only general projects which preclude indexing
"Oriented significanthf to above subject.
at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
RESPIRATORY CIRCULATORY DISORDERS,
PULMONARY CIRCULATORY OBSTRUCTIONS
SEE ALSO BLOOD TREATMENT, BLOOD FILTERS, VENA CAVA
FILTERS
P01HL0628518 0181 Cardiovascular-respiratory
physiology and biochemistry - Regulation of respiration-
Role of vagus nerve (dogs)
POlHL-06285-18 0208 Cardiovascular-respiratory
physiology and biochemistry ■ Composition, properties and
turnover of pulmonary surfactant (human, animals)
POlHL-08805-15 0045 Regulation of ventilation and
pulmonary circulation - Integrated description of
neurochemical respiratory control system
ROlHL-10622-12 Volumes and compliance of pulmonary
circulation (human, dogs)
POlHL-1 1414-11 0004 Thrombosis and atherosclerosis
program Platelet function and nonthrombogenic surfaces
(human)
** POlHL-11414-11 0027 Thrombosis and atherosclerosis
program ■ Thermal memory wire filter to prevent pulmonary
embolism (human, dogs)
POlHL-11414-11 0028 Thrombosis and atherosclerosis
program - Catecholamine metabolism in the lung (rat)
R01HL11802-10 Cardiovascular surgical research (dogs,
sheep, swine, cats, monkeys)
ROlHL-1 1919-08 Pulmonary circulation in surgical heart
disease (human, dogs)
ROIHL 12530-10 Emphysema-Respiratory function in
disease (human, dogs, rats)
** ROlHL-13466-08 Pulmonary platelets in shock, trauma
and embolization (dogs, pigs, rats)
ROIHL 1363907 Factors altering the course of myocardial
dysfunction (cats)
ROlHL-13754-08 Postoperative thromboembolism in
surgical patients (human)
P50HL-14147-08 0007 Specialized center of research in
thrombosis • Radioactive tracers in recognition of
intravascular coagulation (human, dogs)
P50HL-14147-08 0016 Specialized center of research in
thrombosis - Nuclear medicine core laboratory (human,
dogs, rats, rabbits)
P50HL-1418707 0005 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses - Pulmonary
hypertension and cardiac function (dogs, human)
** P50HL14187-07 0008 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses - Pulmonary
thromboembolism (dogs, human)
P50HL14187-07 0012 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses - Vasoactive
mediators in pulmonary disease (human, animal)
P50HL14187-07 0014 Pulmonary SCOR-Chemical
mediators In pulmonary vascular responses - Metabolism
and actions of vasoactive peptides in lung (human,
mammals)
P50HL-14187-07 0015 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses -
Pathophysiologic responses of pulmonary capillary bed
(dog, human)
** P50HL-14187-07 0016 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses ■ Core
pathology service (dogs, rabbits, human)
P50HL-14217-08 0052 Specialized center of research in
thrombosis - Radioisotope nuclear medicine section
(human, dog)
ROlHL-14717-06 Hemodynamics and heart structure-
Ventricular overload (dogs)
POlHL-14985-07 0007 Adaptation to hypoxia - Control of
pulmonary circulation, histamine and the sympathetlcs
(animals)
P01HL14985-07 0010 Adaptation to hypoxia - Pulmonary
mast cell (animals)
■* POlHL-14985-07 0011 Adaptation to hypoxia -
Prostaglandins in the control of the pulmonary circulation
(animals)
P60HL-15160-07 0015 Center for sickle cell disease -
Lung function abnormalities in sickle cell
hemoglobinopathies (human)
P60HL-I5169-05 0015 Support for center for sickle cell
disease ■ Pathophysiology of acute pulmonary infiltrates in
sickle cell disease (human)
• P01HL15486-06 0006 Studies on thrombosis - Clinical
investigation unit
ROlHL-15580-06 Humoral control of pulmonary and
systemic circulation (animals)
• POlHL-15596-05 0007 Coagulation, fibrinolysis,
hemostasis and hepatitis - Structural studies and
fractionation of urokinase (human)
ROlHL-16952-05 Cardiovascular pathology (rats, rabbits)
P60HL-1726504 0007 Community blood resource center
support ■ Research -Massive transfusion and trauma
(human)
ROlHL-17355-04 Pulmonary vascular adjustments in
circulatory collapse (dogs, rats)
(contd)
RES
Pulmonary and circulatory alterations
Diagnostic techniques in venous
PbOHL U66b04 0027 Study o) ischemic heart disease
Positron imsiinj ol leiional myocardial peitusion (human,
dog)
ROIHL U71903 Lung inlury. substrate utilisation, oxygen
toxicity (tats, rabbits, dogs)
•* POIHL 17731 04 0006 Physiological basis of pulmonary
disease Ventilation perlusion ratios (human, dogs)
POIHL 17813 04 0001 Lung disease and the oxygenation
ot blood and tissue Diltuse interstitial lung disease
Pathophysiology (human, dogs)
*• ROIHL 1807004 Regulation ot mtrapulmonary airways
and vessels (human, animals)
•• POIHL 18576 03 0013 Thiombosis research program
protect Early warning and monitoring test systems in
thrombotic disease (human)
R01HL18738 02 Prevention ol postoperative venous
thrombi (human, cattle)
ROIHL 1881503 Surgical vascular disorders (human.
dogs)
ROIHL 1887302 Early radiologic diagnosis ot cardiac
failure (monkey)
** P50HL1915502 0004 Pathophysiology ol pulmonary
edema Physical and chemical eflects ot multiple
pulmonary emboli (sheep)
*• ROIHL 2055402 Memory alloy-lilters for venous emboli
(dogs)
ROlHL-2118202 Active tension and shortening in cardiac
hypertrophy (rabbits)
** ROlHL-21518-01 Improvement in regional ventilation-
perfusion resolution (human)
** ROIHL 2154801 Pathogenesis ot pulmonary
thromboembolic disease (human, mammals)
ROlHL-2157201 Natural history of the postphlebitic
syndrome
ROlHL-22582-01
induced by IGE
ROlHL-22852-01
thromboembolism (human)
RESPIRATORY CIRCULATORY DISORDERS,
PULMONARY HEART DISEASE
SEE ALSO HEART DISORDERS, VALVUUR, PULMONARY VALVE
STENOSIS
SEE ALSO RESPIRATORY CIRCUUTORY DISORDERS,
PULMONARY HYPERTENSION
** ROlHL-1000913 Regional lung function in man
** P01HL10342-13 0008 The integrated function of
respiration and circulation - Respiratory mechanics and the
circulation (human, dogs)
** POlHL-10436-13 0005 A multidisciplinary study of
congenital heart disease - Pulmonary physiology in
congenital heart disease (human)
** POIHL- 10436- 13 0008 A multidisciplinary study of
congenital heart disease - Physiologic consequences of
chronic hypoxemia (human)
M POlHL-12373-10 Cardiopulmonary physiology and
pathophysiology
** P50HL-14187-07 0005 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses - Pulmonary
hypertension and cardiac function (dogs, human)
POlHL-14388-07 0229 Regulation of the circulation in
pathological states - Mechanism of postural hypotension
(human)
ROlHL-16329-04 Cardiac surgical effect on heart function
in infants (human)
R01HL-16784-03 Lung tissue and water volume (human,
dogs)
ROlHL-17711-05 Mechanism of hypoxic regulation ot lung
circulation (rats, cats, guinea pigs)
** POlHL-17731-04 0006 Physiological basis of pulmonary
disease - Ventilation-perlusion ratios (human, dogs)
** ROlHL-18191-04 Models of hypoxic pulmonary
hypertension (cattle, minipigs)
ROlHL-18850-03 Classification code for Frank orthogonal
ECG
"* R23HL-22621-01 Blood cell-mediated pulmonary (human)
** ROlHL-22622-01 Sleep apnea and desaturation-
mechanisms and incidence (human)
*• ROlHL-22910-01 Control of breathing pattern in health
and disease (human, animals)
** NOlHR-62942-04 Nocturnal oxygen therapy in chronic
hypoxic lung disease (humam)
•* NOlHR-62943-05 Nocturnal oxygen therapy in chronic
hypoxic lung disease (human)
" NOlHR-62944-04 Nocturnal oxygen therapy in chronic
hypoxic lung disease (human)
** NOlHR-62945-04 Nocturnal oxygen therapy in chronic
hypoxic lung disease (human)
" NOlHR-62946-04 Nocturnal oxygen therapy in chronic
hypoxic lung disease (human)
" NOlHR-62947-04 Nocturnal oxygen therapy in chronic
hypoxic lung disease (human)
RESPIRATORY CIRCULATORY DISORDERS,
PUUAONARY HYPERTENSION
SEE ALSO RESPIRATORY CIRCULATORY DISORDERS,
PULMONARY HEART DISEASE
POlHL-06285-18 0146 Cardiovascular-respiratory
physiology and biochemistry - Pathogenesis and detection
ot hypoxic pulmonary edema (human, animals)
POlHL-06308-18 0012 Mechanisms and therapy of
circulatory disease - Echocardiographic evaluation of
hemodynamics of arrhythmia (human)
M
461
POIHI 0683b 17 0053 Cardiovascular disease
Vasodilating diugs (human)
POIHL 08805 15 0048 Regulation o( venlilalion and
pulmonary circulation Permeability of alveole Capillary
membrane in normal pulmonary hypertensive lung
POIHL 08805 15 0049 Regulation ol ventilation and
pulmonary circulation Pulmonary hypertension produced
by Oirofilaria immitis in the dog
POIHL 10436 13 0002 A multidisciplinary study of
congenital heart disease Myocardial performance,
metabolism and ultiaslructuie (human, cats, rats)
ROIHL 10834 09 Fetal and neonatal pulmonary circulation
(goats)
ROIHL 11802-10 Cardiovascular surgical research (dogs,
sheep, swine, cats, monkeys)
ROIHL 12530-10 Emphysema Respiratory function in
disease (human, dogs, rats)
P50HL 14187 07 0005 Pulmonary SCOR Chemical
mediators in pulmonary vascular responses Pulmonary
hypertension and cardiac function (dogs, human)
ROIHL 1471706 Hemodynamics and heart structure
Ventricular overload (dogs)
POlHL-14985-07 Adaptation to hypoxia
POIHL 14985 07 0005 Adaptation to hypoxia Control
mechanisms in the pulmonary microcirculation (animals)
' POIHL 14985 07 0007 Adaptation to hypoxia Control of
pulmonary circulation, histamine and the sympathetics
(animals)
POlHL-14985-07 0010 Adaptation to hypoxia - Pulmonary
mast cell (animals)
POlHL-14985-07 0011 Adaptation to hypoxia -
Prostaglandins in the control of the pulmonary circulation
(animals)
POlHL-1498507 0014 Adaptation to hypoxia - High
altitude pulmonary edema (human, rats, dogs)
* POlHL-14985-07 0015 Adaptation to hypoxia - Pregnancy
at high altitude (human, animals)
* ROlHL-15580-06 Humoral control of pulmonary and
systemic circulation (animals)
* ROIHL 17322-04 Functional characteristics of smooth
muscle isolated from lung (animals)
* ROlHL-17581-03 Patent ductus arteriosus and pulmonary
hypertension (dogs)
ROlHL-177 11-05 Mechanism of hypoxic regulation of lung
circulation (rats, cats, guinea pigs)
P01HL17813-04 Lung disease and the oxygenation of
blood and tissue
POlHL-17813-04 0001 Lung disease and the oxygenation
of blood and tissue - Diffuse interstitial lung disease -
Pathophysiology (human, dogs)
POIHL 17813-04 0008 Lung disease and the oxygenation
of blood and tissue - Pulmonary regulation of systemic
blood pressure (human, rabbits, rats)
ROlHL-18070-04 Regulation of intrapulmonary airways
and vessels (human, animals)
ROlHL-18191-04 Models of hypoxic pulmonary
hypertension (cattle, minipigs)
ROlHL-18371-03 Pulmonary hypertension and ventilation
pathophysiology (dogs)
ROlHL-18848-03 Etiology and development of congenital
heart disease (dogs, cats)
ROlHL-19225-02 Types and mechanims of pulmonary
hypertension
Types and mechanims of
- Structural changes (human.
M
ROlHL-19225-02 0001
pulmonary hypertension
animals)
ROlHL-19225-02 0002
pulmonary hypertension
(pigs)
ROlHL-19225-02 0003
pulmonary hypertension
and rats
' ROlHL-19225-02 0004
pulmonary hypertension
Types and mechanims of
- Effect of aorto-pulmonary shunt
Types and mechanims ot
- Cardiopulmonary function in pigs
Types and mechanims of
^ Structural changes in human
pulmonary circulation (human, animals)
ROlHL-19394-03 Biochemistry and regulation of taurine in
the heart (rats, guinea pigs, cats)
ROlHL-20087-02 Developmental processes in pulmonary
hypertension (rats)
ROlHL-207 19-02 Cold induced pulmonary hypertension
(cattle)
POlHL-226 19-01 0009 Cellular mechanisms of heart
failure - Sarcoplasmic reticulum in cardiac, skeletal and
smooth muscle (rabbits, dogs)
ROlHL-232 10-01 Biology of normal and hypertrophied
pulmonary vessels (cat, human)
ROlHL-23224-01
muscle (rat. cat)
ROlHL-23232-01
Hypoxia and pulmonary vascular smooth
Effect of hypoxia on PVSM and its
precursor cells
ROlHL-23542-01
Pulmonary vascular smooth muscle cell
dynamics (rat, rabbit)
** NOlHR-62920-02 Noninvasive diagnosis of pulmonary
hypertension (dog, human)
RESPIRATORY CIRCULATORY DISORDERS,
PUUMONARY ISCHEMIA AND HYPOXIA
POlHL-06285-18 0136 Cardiovascular-respiratory
physiology and biochemistry - Fetal microcirculation in
utero (rabbits, lambs)
** POlHL-06285-18 0146 Cardiovascular-respiratory
physiology and biochemistry - Pathogenesis and detection
of hypoxic pulmonary edema (human, animals)
RfS
ROIHI 10009 13 Regional lung function in man
ROIHI 11802 10 Caidiovasculai surgical research (dogi,
sheep, swine, cats, monkeys)
ROIMI 13466 08 Pulmonary platelets in shock, trauma
and embolization (dogs. pigs, rats)
P50HI 14187 0/ 001? Pulmonary SCOR Chemical
mediators in pulmonary vascular responses Vasoactiv*
mediators in pulmonary disease (human, animal)
P50H1 14187 07 0015 Pulmonary SCOR Chemical
mediators in pulmonary vascular responses
Pathophysiologic responses of pulmonary capillary bed
(dog, human)
* P50HL 14187 07 0016 Pulmonary SCOR Chemical
mediators in pulmonary vascular responses Core
pathology service (dogs, rabbits, human)
P50HL 14214 07 0022 Newborn lung center lor hyaline
membrane disease Functional integrity of surfactant
system Hyaline membrane disease (lamb, rat)
P50HL 1421407 0029 Newborn lung center for hyaline
membrane disease The diving reflex Perinatal asphyxia,
pulmonary ischemia and HMD (sheep)
H POIHL 1498507 Adaptation to hypoxia
POIHL 14985 07 0002 Adaptation to hypoxia Oxygen
transport in man at high altitude
•* POIHL 1498507 0003 Adaptation to hypoxia Hypoxia
and oxygen transport (human, dogs)
POIHL 14985 07 0004 Adaptation to hypoxia Control of
breathing in respiratory failure (human, dogs)
>• POIHL 14985-07 0005 Adaptation to hypoxia Control
mechanisms in the pulmonary microcirculation (animals)
POIHL 14985 07 0007 Adaptation to hypoxia Control of
pulmonary circulation, histamine and the sympathetics
(animals)
POlHL-14985-07 0009 Adaptation to hypoxia - Influence
of chemosensitivity on control of breathing during sleep
(human, dogs)
POlHL-14985-07 0010 Adaptation to hypoxia Pulmonary
mast cell (animals)
POlHL-1498507 0011 Adaptation to hypoxia -
Prostaglandins in the control of the pulmonary circulation
(animals)
** POlHL-14985-07 0012 Adaptation to hypoxia - Direct
effect of hypoxia on pulmonary vascular smooth muscle
(rats, dogs)
** POlHL-14985-07 0013 Adaptation to hypoxia - Chronic
mountain sickness (men)
POlHL-15194-07 0011 Pathophysiology of
cardiopulmonary dysfunction - Distribution of ventilation-
Oxygen effects on intrapulmonary shunting (human)
POlHL-17731-04 0007 Physiological basis of pulmonary
disease - Theoretical gas exchange
** ROlHL-18143-03 Surgery and pulmonary tissue alterations
(dogs, rats, human)
** ROlHL-18191-04 Models of hypoxic pulmonary
hypertension (cattle, minipigs)
ROlHL-20566-02 Lactate metabolism in the lung (rats)
R23HL-21 116-02 Mechanisms of membrane and tissue
damage in lung (dogs, rabbits)
** ROlHL-22641-01 Ventilation, perfusion, and systemic
arterial reflexes (dogs)
** R23HL-22932-01 Effect of carbon dioxide on local gas
exchange (dogs)
RESPIRATORY DISORDERS (GENERAL)
SEE ALSO HOSPITALS, INTENSIVE CARE UNITS, RESPIRATORY
SEE ALSO HYPERSENSITIVITY, RESPIRATORY
HYPERSENSITIVITY
SEE ALSO INJURIES, CHEST
SEE ALSO RESPIRATORY ASSIST AND OXYGEN
ADMINISTRATION. AEROSOL THERAPY
SEE ALSO RESPIRATORY CIRCULATORY DISORDERS
SEE ALSO RESPIRATORY INFECTIONS
** ROlHL-00759-29 Regulation of electrolyte and acid base
equilibrium (dogs)
M POlHL-06285-18 Cardiovascular-respiratory physiology and
biochemistry
POlHL-07896-15 0021 Environmental biomedical research
program - Liquid breathing and lung lavage (human)
** ROlHL-08789-11 Respiratory muscles and ventilatory
control in man (and dogs)
M POlHL-08805-15 Regulation of ventilation and pulmonary
circulation
M POlHL-10342-13 The integrated function of respiration
and circulation
POlHL-11310-12 0093 Mechanisms of cardiovascular
disease - Multiple dipole electrocardiogram project (human,
dogs)
** ROlHL-13172-10 Post-trauma lung mechanics and fluid
exchange (human, dogs, monkeys)
ROlHL-13888-15 Regulation of respiration
** P50HL-14136-07 9003 Pulmonary SCOR -Airways
obstructive diseases - Pathology core (human, dogs)
M POlHL-14580-07 Program project in respiratory mechanics
** ROlHL-14692-06 Alpha 1 antitrypsin deficiency and
pulmonary disease (human)
** ROlHL-15614-04 Heredity and oxygen-Effects on health of
heart-lungs (South America)
ROlHL-15659-05 Dynamic isolation studies ol control ol
respiration (human)
POlHL-16411-04 0004 Blood systems in coagulation and
vessel disease - Platelets reactions in vascular injury
(human, animals)
(contd)
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subproiects descnbmg specific research aspects.
See Appendix for investigator's name and grant number.
Mass
Vermont Lung Center - School lung
Vermont Lung Center - Health
RES
M POlHL-16748-05 Cellular and immunological basis of
pulmonary diseases
** POlHL-16748-05 0002 Cellular and immunological basis
of pulmonary diseases ■ Immunological function of alveolar
macrophages (rabbits, sheep, mice)
ROlHL-16784-03 Lung tissue and water volume (human,
dogs)
M P60HL-17292-04 Vermont Lung Center
P60HL-17292-04 0008 Vermont Lung Center - Respiratory
physiology-Teaching, learning and auditing problem-solving
skills
" P60HL-17292-04 0013 Vermont Lung Center ■ Regional
management of respiratory disease program
" P60HL-17292-04 0020 Vermont Lung Center •
information -Education project
** P60HL-17292-04 0021
education project
** P60HL-17292-04 0023
information resources
** P60HL-17292-04 0024 Vermont Lung Center - Education
and media resources unit
M POlHL-17731-04 Physiological basis of pulmonary disease
** POlHL-17731-04 0006 Physiological basis of pulmonary
disease - Ventilation-perfusion ratios (human, dogs)
M POlHL-17813-04 Lung disease and the oxygenation of
blood and tissue
** ROlHL-18070-04 Regulation of intrapulmonary airways
and vessels (human, animals)
" R01HL-I8181-04 Surfactant metabolism -Alveolar cells and
lung disease (mice, rabbits)
ROlHL-18328-03 Hemoglobin function and tissue
oxygenation (human, dogs)
R01HL-I8952-03 Metabolism in perfused fetal and
newborn rabbit lungs
R01HL-19I 18-03 Measurement of airways mechanics
(human, dog)
ROlHL-19715-02 Respiratory tract deposition of
hygroscopic aerosols (dogs, human)
M POlHL-19717-02 Response of the lung to injury
** POlHL-19717-02 0038 Response of the lung to injury -
Interstitial lung disease-Clinical, pathologic and
epidemiologic
•* POlHL-19717-02 0046 Response of the lung to injury -
Bioengineering section
ROlHL-20675-02 Alveolar macrophage function in man
** ROlHL-20783-02 Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
ROlHL-2 11 56-02 Antitrypsin and other causes of chronic
lung disease
M POlHL-2 1584-02
abnormal states
** R01HL-22333-01
(rats)
** R23HL-22437-01 Leukotactic mediators in lung
inflammatory reactions (rats, rabbits, human)
" ROlHL-22910-01 Control of breathing pattern in health
and disease (human, animals)
** ROlHL-23981-01 Acute alveolar injury (dogs)
RESPIRATORY DISORDERS, ACIDOSIS,
RESPIRATORY
P50HL-142 18-07 0018 Pulmonary SCOR-Newborn lung
center - Whole body buffering in acute hypercapnia (dogs)
ROlHL-14461-08 Cardiac metabolism in heart failure
(rats)
** ROlHL-15307-06 Central nervous control of renin and
blood pressure (dogs)
ROlHL-17355-04 Pulmonary vascular adjustments in
circulatory collapse (dogs, rats)
R01HL-I7873-04 Pathophysiology of exercise-induced
asthma (human)
POlHL-18708-03 0009 Oxygen, energy and contractility in
cardiac tissue - Regulation of oxygen utilization of cardiac
tissue (rats, rabbits)
" P50HL-19185-02 0007 Pulmonary SCOR-Neonatal
respiratory distress syndromes • Sodium bicarbonate and
albumin in resuscitation of preterm infants (human)
ROlHL-20196-02 Regulation of coronary arterial smooth
Respiratory mechanics in normal and
Cellular basis of small airways function
muscle
ROlHL-207 19-02
(cattle)
ROlHL-21500-02
stress (dogs)
ROlHL-22650-01
Cold induced pulmonary hypertension
Performance of respiratory muscles under
Regulatory mechanisms of erythropoietin
production (human, rats, mice)
RESPIRATORY DISORDERS, ATELECTASIS
SEE ALSO BODY CAVITY DISORDERS, PLEURAL.
PNEUMOTHORAX (GENERAL)
POlHL-06285-18 0208 Cardiovascular-respiratory
physiology and biochemistry - Composition, properties and
turnover of pulmonary surfactant (human, animals)
POlHL-07896-15 0014 Environmental biomedical research
program - Mechanisms of respiration and circulation
(human, dogs)
ROlHL-13172-10 Post-trauma lung mechanics and fluid
exchange (human, dogs, monkeys)
P50HL-14153-07 0017 Johns Hopkins Lung Center-
Chronic diseases of airways • Collateral ventilation and
pulmonary interdependence (pig. dog, human)
POlHL-17731-04 0002 Physiological basis of pulmonary
disease - Biomechanics of the lung (frogs, cats)
Mechanisms of re-expansion pulmonary
462
** ROlHL-18630-03 Pulmonary hemodynamics in atelectasis
and hypoxia (dogs)
ROlHL-18762-03 Post-traumatic pulmonary insufficiency
(dogs)
" R23HL-21050-02
edema (rabbits)
" ROlHL-22641-01 Ventilation, perfusion, and systemic
arterial reflexes (dogs)
RESPIRATORY DISORDERS, BRONCHIAL
DISORDERS (GENERAL)
ROlHL-14271-07 Physico-chemical properties of tracheal
mucus (dogs, frogs)
R23HL-196 19-01 Sem and x ray analysis in human
pulmonary pathology
ROlHL-20783-02 Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
ROlHL-21829-01 Etiology of obstructive airway disease in
children (also monkeys)
** ROlHL-22029-02 Bronchopulmonary resistance to bacterial
infection (mice)
RESPIRATORY DISORDERS, BRONCHIECTASIS
P50HL- 1506 1-07 0007 Response of lung to injury -
Human factors for phagocytosis in normal and diseased
lungs
P50HL-191 71-02 0003 Pulmonary SCOR-Lung injury by
childhood infections - Natural history, host defense defects-
Children with chronic pulmonary disease
ROlHL-19839-09 Factors in youth predisposing to chronic
diseases (former college students)
RESPIRATORY DISORDERS, BRONCHITIS ACUTE
P50HL-14136-07 0003 Pulmonary SCOR -Airways
obstructive diseases - Acute pediatric respiratory disease
RES
and COLD
P50HL-14136-07 9006
obstructive diseases
P50HL-15061-07 0010
Pulmonary SCOR-Airways
Pediatric lung function core
Response of lung to injury - An
inimal model system for the study of bronchiolitis and its
sequellae (dogs)
M P50HL-191 57-02 Studies in cystic fibrosis and
bronchiolitis
** P50HL-191 57-02 0002 Studies in cystic fibrosis and
bronchiolitis - Clinical core
** P50HL-19157-02 0011 Studies in cystic fibrosis and
bronchiolitis - Pathogenesis of bronchiolitis (children)
P50HL-191 71-02 0001 Pulmonary SCOR-Lung injury by
childhood infections - Longitudinal study-Respiratory
infections and lung growth in normal children
" P50HL-191 71-02 0004 Pulmonary SCOR -Lung injury by
childhood infections - Long-term effects of respiratory
infections in early childhood
ROlHL-20347-02 Bolus-response measurement of lung
function (human)
ROlHL-20783-02 Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
ROlHL-21829-01 Etiology of obstructive airway disease in
children (also monkeys)
RESPIRATORY DISORDERS, BRONCHITIS
CHRONIC AND EMPHYSEMA
SEE ALSO PSYCHOLOGY, HABITS. SMOKING
SEE ALSO RESPIRATORY DISORDERS, RESPIRATORY AIRFLOW
DISORDERS
POlHL-04664-18 0010 Cardiovascular and lung dynamics
- Left ventricular dynamics (human)
POlHL-04664-18 0016 Cardiovascular and lung dynamics
- Computerized roentgenographic determination of total
lung capacity
POlHL-06285-18 0190 Cardiovascular-respiratory
physiology and biochemistry - Maximal (airway) flow
(human, dogs)
POlHL-06296-18 0002 Cardiovascular and pulmonary
adaptation to stress - Respiratory muscle blood flow,
mechanics and metabolism (human, dog)
ROlHL-08789-11 Respiratory muscles and ventilatory
control in man (and dogs)
ROlHL-10009-13 Regional lung function in man
POlHL-10436-13 0005 A mulfidisciplinary study of
congenital heart disease - Pulmonary physiology in
congenital heart disease (human)
ROlHL-10622-12 Volumes and compliance of pulmonary
circulation (human, dogs)
** R01HL-12530-10 Emphysema -Respiratory function in
disease (human, dogs, rats)
ROlHL-12564-09 Control of respiration and blood gases
(human, dog)
** ROlHL-12833-09 Genetic and environmental influences on
lung disease (human)
** ROlHL-13645-11 Trypfophan-induced pulmonary
emphysema (cattle, goats, rabbits)
** R01HL-13824-06 Defense mechanisms in pathogenesis of
emphysema (human, dogs)
ROlHL-14102-07 Human physiology at 5360 meters-
Mountain environment
M P50HL 14136-07 Pulmonary SCOR -Airways obstructive
diseases
Pulmonary SCOR-Airways
Experimental airway obstructive
P50HL-14136-07 0001
obstructive diseases
disease (dogs)
P50HL-14136-07 0003
obstructive diseases
and COLD
P50HL-14136-07 0004
obstructive diseases
emphysema (human)
P50HL-14136-07 0005
obstructive diseases
Pulmonary SCOR-Airways
Acute pediatric respiratory disease
Pulmonary SCOR-Airways
Morphometric studies of developing
Pulmonary SCOR-Airways
Radiographic studies of airways
obstructive disease (human)
P50HL-14136-07 0009 Pulmonary SCOR-Airways
obstructive diseases - Tuscon epidemiological study of
airways obstructive disease (human)
P50HL-14136-07 0016 Pulmonary SCOR-Airways
obstructive diseases - Environmental factors in airways
obstructive diseases (human)
** P50HL-14136-07 0017
obstructive diseases
(human)
** P50HL-14136-07 9001
obstructive diseases
** P50HL-14136-07 9002
obstructive diseases
** P50HL-14136-07 9003
obstructive diseases
** P50HL-14136-07 9004
obstructive diseases
** P50HL-14136-07 9005
obstructive diseases
** P50HL-14136-07 9006
obstructive diseases
Pulmonary SCOR-Airways
Pediatric airways obstructive disease
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level
'Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
Pulmonary SCOR-Airways
Biometrics core
Pulmonary SCOR-Airways
Physiology core (human, animal)
Pulmonary SCOR-Airways
Pathology core (human, dogs)
Pulmonary SCOR-Airways
Radiology core (human)
Pulmonary SCOR-Airways
Clinical core
Pulmonary SCOR-Airways
Pediatric lung function core
M P50HL-14153-07 Johns Hopkins Lung Center-Chronic
diseases of airways
'* P50HL-14153-07 0001 Johns Hopkins Lung Center-
Chronic diseases of airways - Genetic and environmental
factors in chronic pulmonary disease (human)
* P50HL-14153-07 0004 Johns Hopkins Lung Center-
Chronic diseases of airways - Macrophage enzymes in lung
injury, inflammation and repair (rabbit)
* P50HL-14153-07 0017 Johns Hopkins Lung Center-
Chronic diseases of airways - Collateral ventilation and
pulmonary interdependence (pig, dog, human)
P50HL-14153-07 0018 Johns Hopkins Lung Center-
Chronic diseases of airways - Pulmonary function core
* P50HL-14153-07 0019 Johns Hopkins Lung Center-
Chronic diseases of airways - Pathology core (human.
animal)
P50HL-14212-07 0004 Correlated studies of pulmonary
fibrosis - Collagen metabolism in lung tissue and lung
cells (human, animal)
P50HL-14212-07 0006 Correlated studies of pulmonary
fibrosis - Alveolar macrophage physiology (human, rodents.
rabbits)
* ROlHL-14262-07 Leukocyte proteases and their lung
targets (human, dogs, rabbits)
ROlHL-14456-07 Lung metabolism-Enzymes in the
pulmonary circulation (human, animals)
* POlHL-14580-07 0005 Program project in respiratory
mechanics - Development and evaluation of tests of
pulmonary function (human)
ROlHL-14663-07 Pulmonary oxygen toxicity in newborn
lung (human, mice)
* ROlHL-14692-06 Alpha 1 antitrypsin deficiency and
pulmonary disease (human)
* R01HL-14700-05 Humoral and lung protease-antiprotease
role in obstructive disease (human)
* ROlHL-14778-10 Proteolytic enzymes and inhibitors in
lung disease (mammals, human)
ROlHL-14844-06 Mucous glycoprotein in human respiratory
epithelium (also wheat)
* ROlHL-14865-07 Biochemical studies on the pathogenesis
of emphysema (human, rats)
* POlHL-14985-07 0004 Adaptation to hypoxia - Control of
breathing in respiratory failure (human, dogs)
POlHL-14985-07 0009 Adaptation to hypoxia - Influence
of chemosensitivity on control of breathing during sleep
(human, dogs)
POlHL-14985-07 0010 Adaptation to hypoxia - Pulmonary
mast cell (animals)
ROlHL-15047-06 Digital computer analysis of the
electrocardiogram (human)
' P50HL-15061-07 0010 Response of lung to injury - An
animal model system for the study of bronchiolitis and its
sequellae (dogs)
P50HL-15092-07 0012 Immune and fibrotic response to
occupational environments - Longitudinal evaluation of
workers exposed to cotton dust
ROlHL-15125-07 Molecular pathology of genetic disorders
in man
POlHL-15194-07 0011 Pathophysiology of
cardiopulmonary dysfunction - Distribution of ventilation-
Oxygen effects on intrapulmonary shunting (human)
POlHL-15194-07 0024 Pathophysiology of
cardiopulmonary dysfunction - Distribution of ventilation-
Airflow limitation in COLD (human)
ROlHL-15307-06 Central nervous control of renin and
blood pressure (dogs)
ROIHL-15526-05 Respiratory mechanics in children
ROlHL-15614-04 Heredity and oxygen-Effects on health of
heart-lungs (South America)
POIHL- 15832-06 Chemical-structural predispositions to
lung injury
(contd)
tis
** POIHL'15832'06 0001 Chemicilslructursl prvdisposltlons
to lung Inluty Chimical composition ot lung connective
tissue proteins (tiuman. animals)
** POIHL 15832 06 0002 Chemical sttuctural predispositions
to lung iniury Connective tissue in lung in development
and tepaii ot Iniury (liuman. rats, mice)
** POIHL 15832 06 0004 Chemical structural predispositions
to lung iniury Proteolytic activity leucocytes in patients
with obstructive lung disease
•• POIHL 1583206 0005 Chemical structural predispositions
to lung injury Pulmonary structure and stress strain
relationships (rats)
POIHL 15832 06 0007 Chemical structural predispositions
to lung injury Inactivation of vasoactive agents by the
lung (human, rats. cats, dogs)
POIHL 15832 06 0010 Chemical-structural predispositions
to lung injury Kinin generating systems in pulmonary
disease (human, animals)
POIHL 1583206 0012 Chemical-structural predispositions
to lung iniury Contractile structures and contractility in
cells ot lung respiratory tract
ROlHL-1597905 Elastase. serum inhibitors and the
vasculature (human, swine)
M POIHL 1611806 Study of emphysema
** POIHL 16118 06 0003 Study of emphysema Degradation
of collagen and elastin (human, hamsters, mice)
** POIHL 16118-06 0004 Study of emphysema Metabolic
activity of pulmonary connective tissue (human, hamsters)
** PO1HL16118-06 0005 Study of emphysema •
(Mechanisms of elastase emphysema (mice)
*• POlHL-1611806 0006 Study of emphysema Metabolism
of elastin (hamsters)
•* ROIHL 16166-05 Structure of alpha-1-antitrypsin in
relation to emphysema (human)
** ROlHL-16463-05 Localization of airways obstruction and
responses
POIHL 16878-05 0001 Control of ventilation in health
and disease Ability of asthmatics to detect added
resistive and elastic loads
ROlHL-17194-03 Comparison of two inherited forms of
alpha-l-antitrypsin (human)
P60HL-1 7292-04 0003 Vermont Lung Center - Subclinical
pulmonary disease in a rural environment (human)
** P60HL- 17 292-04 0018 Vermont Lung Center - Group
patient education-Breathing workshop project
** P60HL 17292-04 0021 Vermont Lung Center - School lung
education project
** P60HL-17292-04 0029 Vermont Lung Center - Computer-
assisted pre-operative evaluation (human)
** ROlHL-17314-04 Effects of anesthesia and loading on
respiration (human, cats)
P01H1.-17417-05 0001 Experimental lung transplantation
- Mechanisms and mediators of lung allograft rejection
(dogs, mice)
** POlHL-17417-05 0005 Experimental lung transplantation
• Lung transplantation in bilateral emphysema (dogs)
ROlHL-17711-05 Mechanism of hypoxic regulation of lung
circulation (rats, cats, guinea pigs)
POlHL-17731-04 0001 Physiological basis of pulmonary
disease • Mechanisms of blood flow and ventilation (dogs)
POlHL-17731-04 0006 Physiological basis of pulmonary
disease • Ventilation-perfusion ratios (human, dogs)
** ROlHL-17768-04 Development of collateral ventilation
(dogs, fish, horses)
*• POlHL-17813-04 0006 Lung disease and the oxygenation
of blood and tissue - Assessment of respiratory muscle
contractile force (human, dogs)
** ROlHL-18308-03 Comprehensive studies of mucociliary
transport (dogs)
** ROlHL-1863202
disease
" ROlHL-1893102
(swine, human)
** P50HL-1915602 0002 Pulmonary SCOR-Chronic diseases
of airways - Early detection of emphysema and chronic
airway obstruction (human, dog)
M P50HL-19170-02 Harvard pulmonary SCOR-Chronic
diseases of the airways
** P50HL-19170-02 0003 Harvard pulmonary SCOR-Chronic
diseases of the airways - Mechanisms of bronchial
reactivity to acute and chronic airway challenge (dog)
" P50HL-19170-02 0004 Harvard pulmonary SCOR-Chronic
diseases of the airways - Exercise, increased ventilation
effect on airway exposure and responses (rodent)
P50HL-19170-02 0005 Harvard pulmonary SCOR-Chronic
diseases of the airways - Pulmonary toxicology of plastics
intermediates and pyrolysis products (animal)
** P50HL-19170-02 0006 Harvard pulmonary SCOR-Chronic
diseases of the airways - Mechanism of overdistension
(human, animal)
** P50HL-19170-02 0008
diseases of the airways
coughing (dogs, human)
** P50HL-1917002 0009 Harvard pulmonary SCOR-Chronic
diseases of the airways - Ventilatory muscle training in
chronic obstructive pulmonary disease (human)
P50HL-1917102 0003 Pulmonary SCOR-Lung injury by
childhood infections - Natural history, host defense defects-
Children with chronic pulmonary disease
P50HL-19171-02 0004 Pulmonary SCOR-Lung injury by
childhood infections - Long-term effects of respiratory
Infections in early childhood
Epidemiologic study of chronic lung
Lung elastic tissue characteristics
Harvard pulmonary SCOR-Chronic
Multiple-transient artificial
463
P50HL 191/1 0? 0005 Pulmonary SCOR lung injury by
childhood infections Chronic lespiialory disease of
children in North Carolina
P50HL 19185 02 0009 Pulmonary SCOR Neonatal
respiratory distress syndromes Nasal continuous positive
airway pressure in hyaline membrane disease (human)
' ROIHL 19237 03 Obstructive lung disease and alveolar
macrophages (human, animals)
P50HL 19362 02 0008 A/S SCOR Atherosclerosis in
nonhuman primates Lung structure and function in
cigarette smoKing (baboon)
ROIHL 1968503 Pathogenesis of inflammation of the lung
(guinea pigs)
POIHL 19717 02 Response of the lung to injury
POIHL 19717 02 0001 Response of the lung to injury
Lung elastic tissue (animals)
POIHL 19717 02 0002 Response of the lung to injury ■
Prolyl hydroxylase, lysyl hydroxylase and lung collagen
biosynthesis (rabbits)
* POIHL 19717 02 0003 Response of the lung to injury -
The role of elastolysis in emphysema (hamsters, rabbits)
POlHL-19717 02 0005 Response of the lung to injury -
Studies on proteolysis and lung disease (human, animals)
POlHL-19717 02 0006 Response of the lung to injury
Glycosaminoglycans and proteoglycans of the lung (human,
rats, hamsters)
POIHL 19717 02 0007 Response of the lung to injury -
Cellular level studies of prostaglandin-like molecules
(cattle)
* POIHL 19717 02 0008 Response of the lung to injury •
Experimental models of lung disease
* POIHL 19717-02 0010 Response of the lung to injury •
Proteoglycans in lung function and structure (hamsters)
* POlHL-1971702 0011 Response of the lung to injury ■
Physiological characterization of the elastase model
(hamsters)
'* POlHL-197 17-02 0012 Response of the lung to injuiy -
Connective tissue biochemistry and enzyme injury of the
lung (hamsters)
'* POlHL-197 17-02 0013 Response of the lung to injury -
Handling of biologically active substances by the diseased
lung (guinea pigs)
** POlHL-19717-02 0014 Response of the lung to injury -
Stereology of epithelialized bronchi in evolving elastase
emphysema (hamsters)
** P01HL1971702 0015 Response of the lung to injury •
Chronic bronchitis and emphysema (hamsters)
** POlHL-19717-02 0016 Response of the lung to injury •
The alveolar macrophage in elastase emphysema (guinea
pigs, hamsters)
** POlHL-197 17-02 0018 Response of the lung to injury -
Lung mechanics and connective tissue composition in
human emphysema
** P01HL19717-02 0019 Response of the lung to injury -
Animal model of fibrosing alveolitis (hamsters, guinea
pigs, rabbits)
** POlHL-197 1702 0020 Response of the lung to injury -
Recording of lung sounds in animal models of disease
(animals)
** P01HL197 17-02 0022 Response of the lung to injury ■
Localization of enzymes and sites of action in experimental
emphysema (hamsters)
POlHL-197 17-02 0028 Response of the lung to injury -
Compensatory grovrth of the lung following pneumonectomy
(rabbits)
POlHL-19717-02 0037 Response of the lung to injuiy -
Catecholamines, prostaglandins and nucleotides in
pulmonary function (animals)
POlHL-19717-02 0038 Response of the lung to injury -
Interstitial lung disease-Clinical, pathologic and
epidemiologic
POIHL 19717-02 0041 Response of the lung to injury -
Cellular immunity in interstitial lung disease (human)
POlHL-197 17-02 0043 Response of the lung to injury -
Asbestosis as a model of usual interstitial pneumonia
(human)
ROlHL-19839-09 Factors in youth predisposing to chronic
diseases (former college students)
ROlHL-20070-02 Alpha-l-antitrypsin deficiency (human,
hamsters)
ROlHL-20347-02 Bolus-response measurement of lung
function (human)
ROlHL-20783-02 Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
ROlHL-20847-02 Respiratory neurochemical control
(human, goats)
** ROlHL-20875-02 Chronic obstructive pulmonary disease-
Familial/genetic (human)
** R23HL 20968-02 Respiratory failure -Control and muscle
dysfunction (human)
M POlHL-209 94-02 Dynamics of neutrophil elastase in the
lung
** POlHL-209 94-02 0001 Dynamics of neutrophil elastase in
the lung - Dynamics of neutrophil elastase in normal
animals (dogs, rabbits)
" POlHL-20994-02 0002 Dynamics of neutrophil elastase in
the lung ■ Neutrophil and neutrophilic elastase in human
lungs
** POlHL-20994-02 0003 Dynamics of neutrophil elastase in
the lung - Neutrophil elastase flux in models of lung
disease (dogs)
RES
POIHI 20994 02 0004 Dynamici of neutiophil ela^t*M in
the lung Mechanism of enzyme inhibition by alpha 1
antitrypsin (cattle)
POIHI 70994 02 0005 Dynamics of neutrophil tl*il<M in
the lung Protease inhibitors in pulmonary inflammation
and emphysema (rabbits)
POIHL 20994 02 0006 Dynamics of neutrophil ela%ta'.e in
the lung Protease inhibitors in human bronchial mucus
POIHL 20994 02 0007 Dynamics of neutrophil elastase in
the lung The etiology of experimental emphysema (dogs)
POIHL 20994 02 0008 Dynamics of neutrophil elastase in
the lung Structure function correlation in experimental
emphysema (human, dogs)
POIHL 20994 0? 0009 Dynamics of neutrophil elastase in
the lung Biosynthesis and degradation of elastin in
emphysema (human, hamsters)
POIHL 20994 02 9001 Dynamics of neutrophil elastase in
the lung Biochemistry and immunology core
' POlHL-20994-02 9002 Dynamics of neutrophil elastase in
the lung Ultraslrutli!- .'' ore
' POlHL-20994-02 9003 Dynamics of neutrophil elastase in
the lung Autoradiography Histology core
' ROIHL 2109502 Enzymes of M tuberculosis and
obstructive lung disease (human, rodents)
• ROlHl-21117-01
disease (human)
ROlHL-21156 02
lung disease
R23HL-2 119902
R23HL 21225-02
Altitude adaptation in chronic lung
Antitrypsin and other causes of chronic
Sound transmission in lung (dog)
Connective tissue precursor molecules in
the lung (rabbits, hamsters)
* ROIHL 21352-02 Community studies of obstructive lung
disease (human)
'* R23HL-2 1369-02 Tracheal mucin synthesis in experimental
bronchitis (rats)
POIHL 21584-02 0002 Respiratory mechanics in normal
and abnormal states - Lung mechanics-Regional
deformation and ventilation (dogs)
'* POlHL-21584-02 0006 Respiratory mechanics in normal
and abnormal states Respiratory mechanics in health and
disease (human, pigs)
ROlHL-2 1649-01 Biochemistry of lung proteoglycans
(mammals)
'* ROlHL-22022-01 Respiratory muscle dysfunction in
respiratory failure (human)
" ROlHL-22313-01 Lung elastic recoil-Age and disease
(human)
** ROlHL-22446-01 Chemical and functional studies of low
copper in lung (pigs)
** ROlHL-22528-02 Early risk predictors for chronic
pulmonary disease (human)
** ROlHL-22622-01 Sleep apnea and desaturation-
raechanisms and incidence (human)
** ROlHL-22723-01 The morphologic basis ot airflow
obstruction (human)
R23HL-2281801 Biosynthesis of human respiratory
mucous glycoprotein (also dog)
** R23HL-22932-01 Effect of carbon dioxide on local gas
exchange (dogs)
" ROlHL-23595-01 Experimental emphysema-Depression of
protease inhibitors (rats, hamsters)
NOlHR-32900-09 Pilot study to standardize the
measurement of 'closing volume' (human)
NOlHR-32902-07 Pilot study to standardize the
measurement of closing volume (human)
** NOlHR-32903-11 Pilot study to standardize the
measurement of 'closing volume' (human)
** NOlHR-62910-02 Fibroprotein networks of pulmonary
alveolar wall (human)
** NOlHR-62931-02 Development and evaluation of
continuing education in pulmonary medicine
NOlHR-62934-02 Evaluate continuing education in
pulmonary medicine
** NOlHR-72901-02 Study of intermittent positive pressure
breathing (data center)
** NOlHR-72902-04 Study of intermittent positive pressure
breathing
** NOlHR-72903-05
breathing
** NOlHR-72904-03
breathing
** NOlHR-72905-03
breathing
** NOlHR-72906-03
breathing
NOlHV-53010-03 NAS-NRC twin registry
RESPIRATORY DISORDERS, BRONCHOSPASM
POlHL-10342-13 0028 The integrated function of
respiration and circulation - Mediator release,
hemodynamics and respiratory function in anaphylaxis
(dogs)
ROlHL-1190708 Mechanisms of physiological responses
to exercise (human, dogs)
P50HL-14153-07 0012 Johns Hopkins Lung Center-
Chronic diseases of airways - Aspirin intolerance in
reversible lung disease (human)
P50HL-19170-02 0007 Harvard pulmonary SCOR-Chronic
diseases of the airways - Therapy effect on airway
obstruction in acute asthma (human)
** ROlHL-21126-02 Exercise-induced bronchospasm in
children
(contd)
Study of intermittent positive pressure
Study of intermittent positive pressure
Study of intermittent positive pressure
Study of intermittent positive pressure
•Excludes RHrtine methodotogy OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
RES
ROlHL-21318-02 Mechanisms of emotions' asthma
triggering effect (human)
NOlHR-7297201 Self-management for asthmatic children
RESPIRATORY DISORDERS, BYSSINOSIS
** P50HL-1 5092-07 0012 Immune and fibrotic response to
occupational environments - Longitudinal evaluation of
workers exposed to cotton dust
P50HL-15092-07 0014 Immune and fibrotic response to
occupational environments - Clinical immunology core
resource
RESPIRATORY DISORDERS, DYSPNEA
" POlHL-08899-14 0031 Tolerance to respiratory gases in
health and disease - Studies in exercise (human, dogs)
POlHL-14985-07 0008 Adaptation to hypoxia - Ventilatory
drive and exercise capacity (human, dogs)
POlHL-16878-05 0001 Control of ventilation in health
and disease Ability of asthmatics to detect added
resistive and elastic loads
POlHL-19717-02 0038 Response of the lung to injury -
Interstitial lung disease -Clinical, pathologic and
epidemiologic
** ROlHL-22910-01 Control of breathing pattern in health
and disease (human, animals)
RESPIRATORY DISORDERS, ENVIRNOMENTAL
POLLUTANTS ASSOCIATED
SEE ALSO RESPIRATORY DISORDERS, BRONCHITIS CHRONIC
AND EMPHYSEMA
POlHL-06285-18 0188 Cardiovascular-respiratory
physiology and biochemistry - Physiology and pharmacology
in regulation of airways-hyperirritability (animals)
** R01HL-12650-08 Environmental pathobiology of the lung
(hamsters, rats)
ROlHL-12833-09 Genetic and environmental influences on
lung disease (human)
ROlHL-13824-06 Defense mechanisms in pathogenesis of
emphysema (human, dogs)
" P50HL-14136-07 0016 Pulmonam SCOR-Airways
obstructive diseases - Environmental factors in airways
obstructive diseases (human)
P50HL-14153-07 0001 Johns Hopkins Lung Center-
Chronic diseases of airways - Genetic and environmental
factors in chronic pulmonaiy disease (human)
M P50HL-14212-07 Correlated studies of pulmonary fibrosis
P50HL-14212-07 0004 Correlated studies of pulmonary
fibrosis - Collagen metabolism in lung tissue and lung
cells (human, animal)
P50HL-14212-07 0007 Correlated studies of pulmonary
fibrosis - Protein metabolism in alveolar macrophages
(rabbits, guinea pigs, human)
" P50HL-14212-07 0012 Correlated studies of pulmonary
fibrosis - Inorganic particulates in tobacco, smoke and
lungs of cigarette smokers (human)
P50HL-14212-07 0013 Correlated studies of pulmonary
fibrosis - Mechanism of beryllium pathogenicity in the lung
(human, rabbit, guinea pig)
" P50HL-14212-07 0015 Correlated studies of pulmonary
fibrosis - Pulmonary defense mechanisms and fibrotic lung
disease (rodents, rabbits)
P50HL-14212-07 0016 Correlated studies of pulmonary
fibrosis - Role of pulmonary alveolar macrophages in
fibrosis (human, rabbit)
M P50HL-15092-07 Immune and fibrotic response to
occupational environments
** P50HL-15092-07 0001 Immune and fibrotic response to
occupational environments - X-ray diffraction study-Dust
exposure in asbestos cement products manufacturing
** P50HL-1 5092-07 0002 Immune and fibrotic response to
occupational environments - Longitudinal study of
sandblasters silicosis (human)
** P50HL-15092-07 0005 Immune and fibrotic response to
occupational environments - Respiratory and immunologic
evaluation of toluene diisocyanate exposure (human)
** P50HL-15092-07 0006 Immune and fibrotic response to
occupational environments - Immunologic studies in
silicosis (human, rabbits, hamsters, guinea pigs)
** P50HL-15092-07 0007 Immune and fibrotic response to
occupational environments - Asbestosis -Cellular immunity,
structure and mineral localization (human)
** P50HL-1 5092-07 0008 Immune and fibrotic response to
occupational environments - Animal models of asbestosis
(hamsters)
** P50HL-15092-07 0010 Immune and fibrotic response to
occupational environments - Characterization of toluene
diisocyanate in industrial environments
** P50HL- 15092-07 0011 Immune and fibrotic response to
occupational environments - Respiratory and immunologic
responses in coffee plant workers
** P50HL-15092-07 0012 Immune and fibrotic response to
occupational environments - Longitudinal evaluation of
workers exposed to cotton dust
** P50HL-15092-07 0013 Immune and fibrotic response to
occupational environments - Epidemiology core resource
** P50HL-15092-07 0014 Immune and fibrotic response to
occupational environments - Clinical immunology core
resource
Metabolism of pulmonary surfactant
M
ROlHL-15273-06
(human, rats)
P50HL-15389-07
pneumonitis
Pulmonary SCOR-Hypersensitivity
464
** P50HL-15389-07 0001 Pulmonary SCOR-Hypersensitivity
pneumonitis - Clinical studies of hypersensitivity
pneumonitis
** P50HL-15389-07 0008 Pulmonary SCOR-Hypersensitivity
pneumonitis - Milwaukee patient study-Hypersensitivity
pneumonitis
P50HL-15389-07 0009 Pulmonary SCOR-Hypersensitivity
pneumonitis - Clinical studies -Pulmonary mycotoxicosis
" P50HL-15389-07 0011 Pulmonary SCOR-Hypersensitivity
pneumonitis - Animal model -Hypersensitivity pneumonitis
in rabbits
** P50HL- 15389-07 0013 Pulmonary SCOR-Hypersensitivity
pneumonitis - Animal model-Pulmonaiy mycotoxicosis
(rabbit, guinea pig)
** P50HL-15389-07 0014 Pulmonary SCOR-Hypersensitivity
pneumonitis - Fractionation and characterization of pigeon
antigens
** P50HL-15389-07 0015 Pulmonary SCOR-Hypersensitivity
pneumonitis - Fractionation and characterization of
thermophilic Actinomycete antigens
P50HL- 15389-07 0019 Pulmonary SCOR-Hypersensitivity
pneumonitis - Microbiology core (human, animal)
R01HL-I6330-06 Aging-tissue injury and repair (rats)
ROlHL-16674-05 Airborne metals and lung permeability
(bullfrogs, rats)
P60HL- 172 92-04 0005 Vermont Lung Center - Mineral
pneumoconioses -Pathogenesis and pathology (human)
M ROlHL-17543-03 Magnetic tracers for diagnosis of lung
disease
** ROlHL-17543-03 0001 Magnetic tracers for diagnosis of
lung disease - Chronic, interstitial lung disease (human,
rabbits)
** ROlHL-17543-03 0002 Magnetic tracers for diagnosis of
lung disease - Magnetite as an index of asbestos exposure
(human)
** ROlHL-17543-03 0003 Magnetic tracers for diagnosis of
lung disease - Occupafionally accumulated magnetite for
diagnosis of lung disease (human)
** ROlHL-17543-03 0004 Magnetic tracers for diagnosis of
lung disease - Magnetite retention, distribution, relaxation
rate, viscosity (rabbits)
ROlHL-177 19-03 Lung injury, substrate utilization, oxygen
toxicity (rats, rabbits, dogs)
ROlHL-18308-03 Comprehensive studies of mucociliary
transport (dogs)
** P50HL-191 56-02 0001 Pulmonary SCOR -Chronic diseases
of airways - Irritability of airways induced by epithelial
damage in healthy subjects (human)
P50HL-19156-02 0005 Pulmonary SCOR-Chronic diseases
of airways - Vagal receptors in the airway -Epithelial injury
and antigen (dog, cat, rabbit)
M P50HL-191 70-02 Harvard pulmonary SCOR -Chronic
diseases of the airways
P50HL-191 70-02 0003 Harvard pulmonary SCOR-Chronic
diseases of the airways - Mechanisms of bronchial
reactivity to acute and chronic airway challenge (dog)
** P50HL19170-02 0004 Harvard pulmonary SCOR-Chronic
diseases of the airways - Exercise, increased ventilation
effect on airway exposure and responses (rodent)
** P50HL-191 70-02 0005 Harvard pulmonaiy SCOR-Chfonic
diseases of the airways - Pulmonary toxicology of plastics
intermediates and pyrolysis products (animal)
P50HL-19362-02 0006 A/S SCOR -Atherosclerosis in
nonhuman primates - Effects of cigarette smoking on
atherosclerosis (baboon)
** P50HL- 193 62-02 0008 A/S SCOR-Atherosclerosis in
nonhuman primates - Lung structure and function in
cigarette smoking (baboon)
R23HL-19584-01 Alveolar macrophage responses to toxic
particle exposure (guinea pigs, human)
** R23HL-196 19-01 Sem and x ray analysis in human
pulmonary pathology
ROlHL-19633-02 Pathogenesis and pharmacology of lung
fibrosis (rats, rabbits)
** ROlHL-19746-03 Proliferation and differentiation of
alveolar macrophages (mice, hamsters)
ROlHL-20783-02 Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
ROlHL-21 120-02 Membrane dynamics in alveolar
macrophages (rabbits)
ROlHL-213 14-02 Respiratory tract secretion of ions, water
and mucus (human, dogs)
** R23HL-22895-01 Smoke inhalation-Biochemical and
cellular responses (rabbits, bacteria)
NOlHR-32902-07 Pilot study to standardize the
measurement of closing volume (human)
** NOlHR-32903-11 Pilot study to standardize the
measurement of 'closing volume' (human)
RESPIRATORY DISORDERS, LARYNGOTRACHEITIS
P50HL-141 36-07 0003 Pulmonary SCOR-Airways
obstructive diseases - Acute pediatric respiratory disease
and COLD
RESPIRATORY DISORDERS, LUNG DISORDERS
(GENERAL)
SEE ALSO BACTERIAL DISEASES, ACTINOMYCETALES
INFECTIONS, TUBERCULOSIS
SEE ALSO CARDIOVASCULAR AND PULMONARY RESEARCH
STUDY SECTION
SEE ALSO DISEASES, SYNDROMES NOT LISTED ELSEWHERE.
GOODPASTURE'S SYNDROME
•Excludes routine methodology OR covers only genera! projects which preclude indexing at the specific level.
**Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
RES
SEE ALSO HYPERSENSITIVITY, RESPIRATORY
HYPERSENSITIVITY, ASTHMA
SEE ALSO RESPIRATORY CIRCULATORY DISORDERS
** ROlHL-01803-23 0022 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Cardiac and pulmonary anaphylaxis
induced by tobacco glycoprotein (rabbits)
POlHL-06285-18 0181 Cardiovascular-respiratory
physiology and biochemistry - Regulation of respiration-
Role of vagus nerve (dogs)
** POlHL-06285-18 0208 Cardiovascular-respiratory
physiology and biochemistry - Composition, properties and
turnover of pulmonary surfactant (human, animals)
** POlHL-10342-13 0008 The integrated function of
respiration and circulation - Respiratory mechanics and the
circulation (human, dogs)
ROlHL-11907-08 Mechanisms of physiological responses
to exercise (human, dogs)
** R01HL-12e50-08 Environmental pathobiology of the lung
(hamsters, rats)
M ROIHL 13885-08 Cystic fibrosis and pulmonary disease
M P50HL-14153-07 Johns Hopkins Lung Center-Chronic
diseases of airways
ROlHL-14495-05 Solid and structural mechanics of lungs
(mammals)
** POlHL-14580-07 0005 Program project in respiratory
mechanics - Development and evaluation of tests of
pulmonary function (human)
M P50HL-15061-07 Response of lung to injury
** P50HL-15061-07 0002 Response of lung to injufy -
Oxidative metabolism, phospholipid synthesis, and response
to toxins (rats)
** P50HL-15061-07 0004 Response of lung to injuiy -
Biochemical abnormalities in connective tissues (rats)
•* P50HL-15061-07 0006 Response of lung to injury -
Complement synthesis by pulmonary macrophages (guinea
pigs, human)
P50HL-15061-07 0007 Response of lung to injury -
Human factors for phagocytosis in normal and diseased
lungs
** P50HL-I5061-07 0009 Response of lung to injury -
Alveolar macrophages (human, rabbits)
•* P50HL-15061-07 0012 Response of lung to injury -
Hyperbaric oxygen, carbon monoxide, and ozone or peroxide
toxicity (rats)
** P60HL-15160-07 0015 Center for sickle cell disease -
Lung function abnormalities in sickle cell
hemoglobinopathies (human)
M POIHL- 15832-06 Chemical-structural predispositions to
lung injury
** P01HL-I5832-06 0001 Chemical-structural predispositions
to lung injury - Chemical composition of lung connective
tissue proteins (human, animals)
** POlHL-15832-06 0004 Chemical-structural predispositions
to lung injury - Proteolytic activity leucocytes in patients
with obstructive lung disease
POlHL-15832-06 0007 Chemical-structural predispositions
to lung injury - Inactivation of vasoactive agents by the
lung (human, rats. cats, dogs)
*• POlHL-15832-06 0008 Chemical-structural predispositions
to lung injury - Interstitial fibrosis-Connective tissue
components in normal and diseased lungs
POlHL-15832-06 0009 Chemical-structural predispositions
to lung injury - Immunology-Enzyme degradation products
of human lung elastin and microfibril
" POlHL-15832-06 0010 Chemical-structural predispositions
to lung injury - Kinin generating systems in pulmonary
disease (human, animals)
POlHL-15832-05 0011 Chemical-structural predispositions
to lung injury - Interaction of cell receptors with vasoactive
agents in pulmonary vascular bed
POlHL-15832-06 9001 Chemical-structural predispositions
to lung injury - Tissue culture studies of lung cell function-
-Core facility
M POlHL-16748-05 Cellular and immunological basis of
pulmonaiy diseases
** POlHL-16748-05 0001 Cellular and immunological basis
of pulmonary diseases - Mechanisms of alveolar
macrophage function and dysfunction (human, rabbits)
** POlHL-16748-05 0004 Cellular and immunological basis
of pulmonary diseases - Cellular and immunological
processes in pulmonary defense systems
M POlHL-16769-05 Pathobiologic and host defense reactions
in the lung
M POlHL-16878-05 Control of ventilation in health and
disease
POlHL-16878-05 0001 Control of ventilation in health
and disease - Ability of asthmatics to detect added
resistive and elastic loads
ROlHL-16920-02 Proteases in normal and immunologically
injured lung (guinea pigs, rabbits)
" P60HL-17292-04 0003 Vermont Lung Center - Subclinical
pulmonary disease in a rural environment (human)
ROlHL-17314-04 Effects of anesthesia and loading on
respiration (human, cats)
POlHL-17382-05 0003 Chemical mediators of acute
pulmonary disorders - Chemical mediators relevant to
allergic reactions (human, guinea pigs)
M P01HL-I7731-04 Physiological basis of pulmonary disease
'• POlHL-17731-04 0001 Physiological basis of pulmonary
disease - Mechanisms of blood flow and ventilation (dogs)
POlHL-17731-04 0007 Physiological basis of pulmonary
disease - Theoretical gas exchange
(contd)
RES
R0IHL'W76804 Dtvalopment ol collateral ventilation
(dots, tisti. Iiorses)
ROIHI 17921 04 Perony radicals to prostaglandins in
vessels and lun|
** ROIHL 18606 04 Pathoienesis and measurement ol
pulmonarY edema (human, rabbits, dogs)
*• ROIHI. 1891803 Characterization ol lunB elastins (rat.
rabbit, chiclten. Rhesus)
•* P50HI 191b3 0? 0006 SCOR-Pulmonary edamas Eitology.
pathogenesis Pulmonary vascular abnormalities in human
lung diseases
•• P50HI 19171 02 0003 Pulmonary SCOR Lung injury by
childhood mlections Natural history, host defense defects
Children with chronic pulmonary disease
•• P50HL 19185 02 0011 Pulmonary SCOR Neonatal
respiratory distress syndromes Complications and
sequelae of neonatal respiratory distress (human)
** R23HL 1961901 Sem and x ray analysis in human
pulmonary pathology
ROIHL 19684 03 Histotypic lung culture in circumfusion
systems (mice)
** R01HL1968503 Pathogenesis of inflammation of the lung
(guinea pigs)
•* P01HL1971702 0005 Response of the lung to injury
Studies on proteolysis and lung disease (human, animals)
P01HL197I7 02 0007 Response of the lung to injury -
Cellular level studies of prostaglandin like molecules
(cattle)
** R01HL1972103 Lung inflammation- Lysosomal proteases
and liposomes (human, rabbits)
U P01HL19737-02 Cellular and molecular aspects of
respiratory physiology
POIHL 19737-02 0001 Cellular and molecular aspects of
respiratory physiology Fatty acid metabolism in type II
alveolar cells (rats)
POlHL-19737-02 0002 Cellular and molecular aspects of
respiratory physiology - Airway smooth muscle in health
and disease (human, animals)
POlHL-19737-02 0009 Cellular and molecular aspects of
respiratory physiology - Regulation of tissue oxygen tension
and body carbon monoxide stores (human, dogs)
*• ROlHL-19760-01 Cellular immune responses of the lung
(mice, guinea pigs)
** ROlHL-19873-03 Pulmonary responses to inhaled antigen
(rabbits, guinea pigs)
** ROlHL-20344-02 Regulation of protein turnover in lung
tissue (rats)
** ROlHL-20347-02 Bolus-response measurement of lung
function (human)
ROlHL-20566-02 Lactate metabolism in the lung (rats)
** ROlHL-20764-02 Elastin and calcification in pulmonary
and vascular disease (human, mammals)
ROlHL-2078302 Airway reactivity-Badrenoceptors and
prostaglandins (guinea pigs)
ROlHL-20787-02 Thromboxanes and prostaglandins -
Biochemical pharmacology (rabbits, human)
ROlHL-20847-02 Respiratory neurochemical control
(human, goats)
ROlHL-2 1105-02 Organ specific drugs-Cardiovascular and
renal effects (dogs)
ROlHL-21314-02 Respiratory tract secretion of ions, water
and mucus (human, dogs)
** ROlHL-21565-02 Pathogenesis of inflammatory lung injury
(rats, rabbits)
** ROlHL-2202201 Respiratory muscle dysfunction in
respiratory failure (human)
** ROlHL-22029-02 Bronchopulmonary resistance to bacterial
infection (mice)
** R01HL-22257-D1 Leukokinesis enhancing factor and lung
infections (human, rats)
ROlHL-22371-01 Vascular changes in lung exposed to
radiation
** ROlHL-22976-01 Nonuniform ventilation and diffusing
capacity (human)
** NOlHR-32902-07 Pilot study to standardize the
measurement of closing volume (human)
RESPIRATORY DISORDERS, PNEUMOCONIOSIS
POlHL-06285-18 0181 Cardiovascular-respiratory
physiology and biochemistry - Regulation of respiration-
Role of vagus nerve (dogs)
POlHL-06285-18 0208 Cardiovascular-respiratory
physiology and biochemistry - Composition, properties and
turnover of pulmonary surfactant (human, animals)
ROlHL-12650-08 Environmental pathobiology of the lung
(hamsters, rats)
P50HL-14212-07 0006 Correlated studies of pulmonary
fibrosis - Alveolar macrophage physiology (human, rodents,
rabbits)
P50HL-14212-07 0007 Correlated studies of pulmonary
fibrosis - Protein metabolism in alveolar macrophages
(rabbits, guinea pigs, human)
P50HL-14212-07 0011 Correlated studies of pulmonary
fibrosis - Pathology core (human, animal)
P50HL-14212-07 0012 Correlated studies of pulmonary
fibrosis ■ Inorganic particulates in tobacco, smoke and
lungs of cigarette smokers (human)
P50HL-14212-07 0015 Correlated studies of pulmonary
fibrosis - Pulmonary defense mechanisms and fibrotic lung
disease (rodents, rabbits)
M P50HL-1509207 Immune and fibrotic response to
occupational environments
465
*• P50HI 15092 0/ 0001 Immune and fibrotic rospo^^e to
occupational environments X ray diffraction study Oust
exposure in asbestos cement products manufacturing
*■ P50HI 1509207 0002 Immune and librotic response to
occupational environments Longitudinal study of
sandblasters silicosis (human)
•* P50HL 15092 0/ 0006 Immune and fibrotic response to
occupational environments Immunologic studies in
silicosis (human, rabbits, hamsters, guinea pigs)
•* P50HL 15092 07 0007 Immune and fibrotic response to
occupational environments Asbestosis Cellular immunity,
structure and mineral localization (human)
•• P50HL 15092 07 0008 Immune and fibrotic response to
occupational environments Animal models of asbestosis
(hamsters)
P50HL 15092 07 0013 Immune and fibrotic response to
occupational environments Epidemiology core resource
P50HL 15092 07 0014 Immune and fibrotic response to
occupational environments Clinical immunology core
resource
** P60HL 17292 04 0005 Vermont Lung Center Mineral
pneumoconioses Pathogenesis and pathology (human)
ROIHL 17543 03 0001 Magnetic tracers for diagnosis of
lung disease Chronic, interstitial lung disease (human,
rabbits)
** ROIHL 17543-03 0002 Magnetic tracers for diagnosis of
lung disease Magnetite as an index of asbestos exposure
(human)
R23HL 19584-01 Alveolar macrophage responses to toxic
particle exposure (guinea pigs, human)
•* R01HL1963302 Pathogenesis and pharmacology of lung
fibrosis (rats, rabbits)
M POlHL-19717-02 Response of the lung to in|ury
POlHL-19717-02 0038 Response of the lung to injury -
Interstitial lung disease -Clinical, pathologic and
epidemiologic
** POlHL-197 17-02 0039 Response of the lung to injury
Lung scanning in alveolitis and asbestolic interstitial
pneumonia (human, animal)
** POIHL 19717-02 0043 Response of the lung to injury
Asbestosis as a model of usual interstitial pneumonia
(human)
** POIHL 1971702 0044 Response of the lung to injury -
Lung sound analysis (human)
** P01HL197 17-02 0045 Response of the lung to injury -
Ultrasound studies (human, hamsters)
ROlHL-20783-02 Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
** R23HL-21134-02 Immune function and fibrogenesis in
silicosis (guinea pigs)
RESPIRATORY DISORDERS, PNEUMONIA
ROlHL-14692-06 Alpha 1 antitrypsin deficiency and
pulmonary disease (human)
POlHL-14985-07 0007 Adaptation to hypoxia - Control of
pulmonary circulation, histamine and the sympathetics
(animals)
POlHL-14985-07 0010 Adaptation to hypoxia ■ Pulmonary
mast cell (animals)
POlHL-16769-05 0002 Pathobiologic and host defense
reactions in the lung • Pathogenesis of complement
dependent injury to the lungs (rabbits)
** P60HL-1 729204 0009 Vermont Lung Center - Controlled
clinical trials on a clinical core unit (human)
** P60HL-17292-04 0030 Vermont Lung Center - Hospital
treatment of pneumonia
POlHL-17417-05 0001 Experimental lung transplantation
- Mechanisms and mediators of lung allograft rejection
(dogs, mice)
P50HL-191 71-02 0003 Pulmonary SCOR -Lung injury by
childhood infections - Natural history, host defense defects-
Children with chronic pulmonary disease
R23HL19619-01 Sem and x ray analysis in human
pulmonary pathology
ROlHL-19760-01 Cellular immune responses of the lung
(mice, guinea pigs)
ROlHL-19777-03 Regulation of hypersensitivity in the lung
(rats, guinea pigs, rabbits, human)
ROlHL-19836-03 Kinin inhibitors detected by use of
receptors (cattle)
ROlHL-19839-09 Factors in youth predisposing to chronic
diseases (former college students)
** ROlHL-20220-03 Anaphylatoxins as inflammatory and
chemotactic agents (guinea pig, rabbit, human)
ROlHL-203 14-02 Host defense against S phcumoniae in
sickle cell disease (human)
ROlHL-2078302 Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
POlHL-2099402 0005 Dynamics of neutrophil elastase in
the lung - Protease inhibitors in pulmonary inflammation
and emphysema (rabbits)
POlHL-20994-02 0008 Dynamics of neutrophil elastase in
the lung ■ Structure-function correlation in experimental
emphysema (human, dogs)
ROlHL-22257-01 Leukokinesis enhancing factor and lung
infections (human, rats)
RESPIRATORY DISORDERS, PNEUMONIA
ASPIRATION
ROlHL-169 16-04 0011 The role of albumins in lung water
accumulation - Whole body distribution and exchange of
albumin (rabbits, human, monkeys)
•Excludes routine methodology OR covers only general projects which preclude
"Oriented significantly to above subject.
indexing at the specific level.
M Grant has subprojects describing s
See Appendix (or investigator's name
RESPIRATORY DISORDERS, PNEUMONIA
BACTERIAL
SEE ALSO BACIfRIA. MyCOPlASMAIAttS. MyCOPLASMA
PNEUMONIA(*
SEE ALSO BACIERIA. SIRE PIOCOCCACFAE. SIREPIOCOCCUS
PNfUMONIAf
POIHL 14985 07 0011 Adaptation to hypoxia
Prostaglandins in the control of the pulmonary circulation
(animals)
M POIHL 16769 05 Pathobiologic and host defense reactions
in the lung
*• POIHL 1676905 0004 Pathobiologic and host defense
reactions in the lung Pathogenesis of Pseudomonas and
Serratia pneumonias (rabbits)
•• POIHL 1676905 0008 Pathobiologic and host defense
reactions in the lung Pulmonary immunocytologic defense
mechanisms against bacteria (human, animals)
POIHL 16769 05 0009 Pathobiologic and host defense
reactions in the lung Electron microscopy and tissue
culture core laboratory
ROIHL 2000203 Pulmonary complications of viral
infections (children)
•* ROlHL-20170 02 Pulmonary infection in splenectomized
animals (mice)
** ROIHL 20963-01 Experimental lung abscess (rabbits)
P60HL 20985 01 0002 Northern California sickle cell
center ■ Immunization with polyvalent pneumococcal
polysaccharide vaccine (human)
POlHL-20994-02 0003 Dynamics of neutrophil elastase in
the lung Neutrophil elastase flux in models of lung
disease (dogs)
** R23HL-21997-01 Pulmonary immunopathology in the
compromised host (guinea pigs)
R23HL-22823-01 Phagocytic and immune defense
mechanisms of the lung (mice)
P60HL-23282 01 0004 Comprehensive hospital/community
sickle cell center • Bacterial, viral and mycoplasmal
infections and sickle cell disease complications
RESPIRATORY DISORDERS, PNEUMONIA
MYCOPLASMAL (PPLO)
SEE ALSO BACTERIA. MYCOPLASMATALES, MYCOPLASMA
PNEUMONIAE*
P50HL 19171-02 0007 Pulmonary SCOR-Lung injury by
childhood infections Immunologic studies in models of
lower respiratory tract infection (rodents)
" ROlHL-19741-03 Murine CRD -A model of chronic
pulmonary inflammation (mice, rats)
** ROlHL-20063-03 Pathogenesis of pulmonary mycoplasma
infections (guinea pigs, mice)
P60HL-23282-01 0004 Comprehensive hospital/community
sickle cell center • Bacterial, viral and mycoplasmal
infections and sickle cell disease complications
RESPIRATORY DISORDERS, PNEUMONIA
PNEUMOCYSTIS
POlHL-08805-15 0048 Regulation of ventilation and
pulmonary circulation - Permeability of alveolo-CapillatV
membrane in normal pulmonary hypertensive lung
POlHL-19717-02 0038 Response of the lung to injury ■
Interstitial lung disease-Clinical, pathologic and
epidemiologic
** POlHL-19717-02 0039 Response of the lung to injury -
Lung scanning in alveolitis and asbestolic interstitial
pneumonia (human, animal)
** POlHL-1971702 0040 Response of the lung to injury -
Immunosuppressive drugs in usual interstitial pneumonia
(human)
•* POlHL-19717-02 0041 Response of the lung to injury -
Cellular immunity in interstitial lung disease (human)
RESPIRATORY DISORDERS, PNEUMONIA VIRAL
P50HL-14136-07 0003 Pulmonary SCOR-Airways
obstructive diseases • Acute pediatric respiratory disease
and COLD
P50HL-14212-07 0004 Correlated studies of pulmonary
fibrosis • Collagen metabolism in lung tissue and lung
cells (human, animal)
ROlHL-16916-04 0001 The role of albumins in lung water
accumulation - Capillary permeability (dogs, human)
** ROlHL-19651-03 Host factors in pathogenesis of
respiratory disease (human, hamsters)
P60HL-23282-01 0004 Comprehensive hospital/community
sickle cell center ■ Bacterial, viral and mycoplasmal
infections and sickle cell disease complications
RESPIRATORY DISORDERS, PNEUMONITIS
ALLERGIC INTERSTITIAL
POlHL-08805-15 0045 Regulation of ventilation and
pulmonary circulation - Integrated description of
neurochemical respiratory control system
P50HL-14212-07 0014 Correlated studies of pulmonary
fibrosis - Pulmonary lavage cells, secretions in diffuse
intersititial lung disease (human)
** ROlHL-14854-07 Lung and tissue mechanics (monkeys,
dogs)
P50HL-15092-O7 0011 Immune and fibrotic response to
occupational environments - Respiratory and immunologic
responses in coffee plant workers
M P50HL-15389-07 Pulmonary SCOR-Hypersensitivity
pneumonitis
(contd)
ipecific research aspects,
and grant number.
Res
*• P50HL-15389-O7 0001 Pulmonary SCOR-Hypersensitivity
pneumonitis ■ Clinical studies of hypersensitivity
pneumonitis
** P50HL-1538907 0008 Pulmonary SCOR-Hypersensitivity
pneumonitis - Milwaukee patient study-Hypersensitivity
pneumonitis
** P50HL15389-07 0009 Pulmonary SCOR-Hypersensitivity
pneumonitis ■ Clinical studies-Pulmonary mycotoxicosis
*• P50HL15389-07 0010 Pulmonary SCOR-Hypersensitivity
pneumonitis • Clinical study-Pulmonary lesions due to non-
invasive aspergillosis
** P50HL-1 5389-07 0011 Pulmonary SCOR-Hypersensitivity
pneumonitis - Animal model-Hypersensitivity pneumonitis
in rabbits
** P50HL- 15389-07 0012 Pulmonary SCOR-Hypersensitivity
pneumonitis - Animal model -Immunologic lung disease in
guinea pigs
•* P50HL1 5389-07 0013 Pulmonary SCOR-Hypersensitivity
pneumonitis - Animal model-Pulmonary mycotoxicosis
(rabbit, guinea pig)
" P50HL- 15389-07 0014 Pulmonary SCOR-Hypersensitivity
pneumonitis - Fractionation and characterization of pigeon
antigens
** P50HL-15389-07 0015 Pulmonary SCOR-Hypersensitivity
pneumonitis - Fractionation and characterization of
thermophilic Actinomycete antigens
** P50HL-1538907 0016 Pulmonary SCOR-Hypersensitivity
pneumonitis ■ Pulmonary physiology core (human)
*• P50HL15389-07 0017 Pulmonary SCOR-Hypersensitivity
pneumonitis - Immunology core (human)
•* P50HL- 15389-07 0018 Pulmonary SCOR-Hypersensitivity
pneumonitis - Pathology core (human, animal)
•* P50HL-1538907 0019 Pulmonary SCOR-Hypersensitivity
pneumonitis - Microbiology core (human, animal)
P50HL-15389-07 0020 Pulmonary SCOR-Hypersensitivity
pneumonitis - Computer applications and data analysis
core
P01HL15832-06 0007 Chemical-structural predispositions
to lung injury - Inactivation of vasoactive agents by the
lung (human, rats, cats, dogs)
•* POlHL-1583206 0008 Chemical-structural predispositions
to lung injury - Interstitial fibrosis -Connective tissue
components in normal and diseased lungs
POlHL-15832-06 0010 Chemical-structural predispositions
to lung injury - Kinin generating systems in pulmonary
disease (human, animals)
POlHL-15832-06 0012 Chemical-structural predispositions
to lung injury - Contractile structures and contractility in
cells of lung respiratory tract
•* ROlHL-1 7543-03 0001 Magnetic tracers for diagnosis of
lung disease - Chronic, interstitial lung disease (human,
rabbits)
Pathogenesis of inflammation of the lung
R01HI.-19685-03
(guinea pigs)
R01HL19731-03
(human)
R01HL19819-03
(rabbits)
i)01HL-19873-03
Collagen in interstitial fibrosis of lung
Mitogen induced interstitial pneumonitis
Pulmonary responses to inhaled antigen
(rabbits, guinea pigs)
** ROlHL-20063-03 Pathogenesis of pulmonary mycoplasma
infections (guinea pigs, mice)
ROlHL-20783-02 Airway reactivity -B-adrenoceptors and
prostaglandins (guinea pigs)
** R23HL-21918-01 Hypersensitivity pneumonitis in guinea
pigs
ROlHL-22301-01 Immunogenetics of chronic pulmonary
inflammation (mice)
ROlHL-22302-01 Immune responses in the human lung
(also rabbits, monkeys)
*• ROlHL-226 76-01 Pathogenesis in experimental interstitial
pneumonitis (rabbits)
*• NOlHR-62935-02 Histocompatibility antigens -Evolution of
respiratory hypersensitivity (human)
RESPIRATORY DISORDERS, PNEUMONITIS
AUERGIC INTERSTITIAL, FARMER'S LUNG
P5OHL-15389-07 0001 Pulmonary SCOR-Hypersensitivity
pneumonitis - Clinical studies of hypersensitivity
pneumonitis
P5OHL1538907 0009 Pulmonary SCOR-Hypersensitivity
pneumonitis - Clinical studies -Pulmonary mycotoxicosis
P50HL-1 5389-07 0015 Pulmonary SCOR-Hypersensitivity
pneumonitis - Fractionation and characterization of
thermophilic Actinomycete antigens
ROlHL-20815-02 Validation of indirect tests of small
aimays function (human, dogs, ponies)
MSPIRATORY DISORDERS, PULMONARY
ALVEOLAR PROTEINOSIS
R01HL13885-08 0005 Cystic fibrosis and pulmonary
disease - Evaluation of lobar pulmonary lavage (human)
** ROlHL-19628-03 Mechanisms of pulmonary alveolar
proteinoses (human, rats)
•* ROlHl-20547-02 Glycoproteins in pulmonary alveolar
proteinosis (human)
R23HL-21251-01 Metabolism of neutral lipids in the
pulmonary alveolus (rabbits)
*• R01HL-2U80-01 Structure, source and functions of
ahnolar glycoproteins (human, rabbits)
466
RESPIRATORY DISORDERS, PULMONARY EDEMA
POlHL-06285-18 0145 Cardiovascular-respiratory
physiology and biochemistry - Pulmonary, pleural and
systemic microcirculation (animals)
** POlHL-06285-18 0146 Cardiovascular-respiratory
physiology and biochemistry - Pathogenesis and detection
of hypoxic pulmonary edema (human, animals)
POlHL-07896-15 0009 Environmental biomedical research
program - Decompression sickness and computation of safe
diving tables (human, animals)
** POlHL-07896-15 0045 Environmental biomedical research
program - Extravascular lung water dynamics in pulmonary
oxygen toxicity (human, baboons)
** POlHL-08805-15 0025 Regulation of ventilation and
pulmonary circulation - Pulmonary edema (rabbits)
ROlHL-10009-13 Regional lung function in man
** POlHL-10342-13 0006 The integrated function of
respiration and circulation - Lung inflation effects on
pulmonary vasculature and interstitial space (dogs)
" POlHL-10342-13 0008 The integrated function of
respiration and circulation - Respiratory mechanics and the
circulation (human, dogs)
POlHL-11678-11 0017 Cardiovascular dynamics and their
control - Overall control of circulation -Mathematical
analyses
** POlHL-1 1678-11 0020 Cardiovascular dynamics and their
control - Circulatory and pulmonary fluid dynamics during
pulmonary edema
** POlHL-1 1678-11 0036 Cardiovascular dynamics and their
control - Pulmonary capillary dynamics and edema (dogs)
** POlHL-11678-11 0058 Cardiovascular dynamics and their
control - Overall control of the circulation-Computer
analysis
ROlHL-11802-10 Cardiovascular surgical research (dogs,
sheep, swine, cats, monkeys)
ROlHL-12530-10 Emphysema-Respiratory function in
disease (human, dogs, rats)
** ROlHL-12879-09 0010 Pulmonary transport and
metabolism in vivo - Lung morphometry in control and
edematous lungs (dogs)
ROlHL-12974-10 Tracer kinetics, flows and masses in
body organs (human, dogs)
ROlHL-131 72-10 Post-trauma lung mechanics and fluid
exchange (human, dogs, monkeys)
** R01HL-13596-07 Clearance of plasma proteins from
alveoli
ROlHL-13623-08 Atrial receptors (dogs)
** ROlHL-13645-11 Tryptophan-induced pulmonary
emphysema (cattle, goats, rabbits)
** POlHL-13738-08 0001 Cardiac assist devices and
artificial hearts - Cardiac assist devices (human, sheep)
ROlHL-13901-08 Ontogeny, ultrastructure, function in
lymphatic system (birds, fish, mammals)
ROlHL-14102-07 Human physiology at 5360 meters-
Mountain environment
P50HL-14187-07 0012 Pulmonary SCOR -Chemical
mediators in pulmonary vascular responses - Vasoactive
mediators in pulmonary disease (human, animal)
P50HL-141 87-07 0014 Pulmonary SCOR -Chemical
mediators in pulmonary vascular responses Metabolism
and actions of vasoactive peptides in lung (human,
mammals)
" P50HL-142 14-07 0025 Newborn lung center for hyaline
membrane disease - Pulmonary vascular permeability and
lung water-Hyaline membrane disease (sheep)
•* P50HL-14218-07 0017 Pulmonary SCOR-Newborn lung
center - Transvascular fluid exchange, vasoactive mediators
in RDS (sheep, cat)
Regulation of the circulation in
Pharmacology of the coronary
Regulation of the circulation in
Experimental myocardial infarction
POlHL-14388-07 0220
pathological states -
circulation in man
POlHL-14388-07 0221
pathological states -
(dogs)
POlHL-14985-07 0003 Adaptation to hypoxia - Hypoxia
and oxygen transport (human, dogs)
POlHL-14985-07 0005 Adaptation to hypoxia - Control
mechanisms in the pulmonary microcirculation (animals)
POlHL-14985-07 0010 Adaptation to hypoxia - Pulmonary
mast cell (animals)
POlHL-14985-07 0014 Adaptation to hypoxia - High
altitude pulmonary edema (human, rats, dogs)
ROlHL-15593-05 Prolonged extracorporeal cardiopulmonary
support (rats, sheep, rabbits)
POlHL-15832-06 0007 Chemical-structural predispositions
to lung injury - Inactivation of vasoactive agents by the
lung (human, rats, cats, dogs)
ROlHL-16784-03 Lung tissue and water volume (human,
dogs)
ROlHL-169 16-04 The role of albumins in lung water
accumulation
ROlHL-16916-04 0001 The role of albumins in lung water
accumulation - Capillary permeability (dogs, human)
ROlHL-16916-04 0002 The role of albumins in lung water
accumulation - Lung water balance -Forces, models and
albumin concentrations (rabbits, dogs)
ROlHL-169 16-04 0011 The role of albumins in lung water
accumulation - Whole body distribution and exchange of
albumin (rabbits, human, monkeys)
ROlHL-17355-04 Pulmonary vascular adjustments in
circulatory collapse (dogs, rats)
I nwtiia nwthodolegy OR covars only general projects which preclude indexing at the specific level
**9iiMtMl significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
RES
POlHL-17417-05 0001 Experimental lung transplantation
- Mechanisms and mediators of lung allograft rejection
(dogs, mice)
POlHL-17731-04 0006 Physiological basis of pulmonary
disease - Ventilation-perfusion ratios (human, dogs)
ROlHL-17768-04 Development of collateral ventilation
(dogs, fish, horses)
" ROlHL-17800-04 Pulmonary reflexes -Central pathways
(cats, dogs, rabbits)
** ROIHL 18606-04 Pathogenesis and measurement of
pulmonary edema (human, rabbits, dogs)
ROIHL 19010-03 Metabolism and cell biology of lung
surfactant system (rabbits, sheep)
** ROlHL-19089-03 Diastolic properties of the left ventricle
(human, dogs)
M P50HL-19153-02 SCOR -Pulmonary edemas-Eitology,
pathogenesis
" P50HL-19153-02 0001 SCOR -Pulmonary edemas-Eitology,
pathogenesis - Prostaglandins and the lung circulation
(sheep)
** P50HL-19153-02 0002 SCOR -Pulmonary edemas-Eitology,
pathogenesis - Lung fluid dynamics-Classical mediators
and their inhibitors (sheep)
** P50HL-19153-02 0003 SCOR -Pulmonary edemas-Eitology.
pathogenesis - Possible inhibitors of mediator release and
pulmonary vascular response (sheep)
P50HL 19153-02 0004 SCOR-Pulmonary edemas-Eitology,
pathogenesis Physical mechanisms in lung transvascular
transport- Math models (sheep)
** P50HL 19153 02 0006 SCOR-Pulmonary edemas-Eitology,
pathogenesis - Pulmonary vascular abnormalities in human
lung diseases
** P50HL-19153-02 0007 SCOR-Pulmonary edemas-Eitology,
pathogenesis • Core-Experimental laboratories and support
facilities
P50HL-19I53-02 0008 SCOR-Pulmonary edemas-Eitology.
pathogenesis Core-Biomedical engineering
M P50HL-19155-02 Pathophysiology of pulmonary edema
** P50HL-19155-02 0001 Pathophysiology of pulmonary
edema - Pulmonary edema study unit (human, dog)
** P50HL-19155-02 0002 Pathophysiology of pulmonary
edema - Non invasive measurement of protein turnover in
human lung (also sheep)
P50HL-19155-02 0004 Pathophysiology of pulmonary
edema ■ Physical and chemical effects of multiple
pulmonary emboli (sheep)
** P50HL-19155-02 0005 Pathophysiology of pulmonary
edema - Protein exchange sites and lymph protein
concentration in lung (mice, sheep)
P50HL-19155-02 0008 Pathophysiology of pulmonary
edema - Core microscopy laboratory
P50HL-19170-02 0004 Harvard pulmonary SCOR-Chronic
diseases of the airways - Exercise, increased ventilation
effect on airway exposure and responses (rodent)
** ROlHL-19298-03 Pulmonary hemodynamics (dogs, cats)
** ROlHL-19678-01 Quantification of intrathoracic fluid by
impedance (human, dogs)
ROlHL-201 10-02 Microwave methods of lung water
measurement (dogs, phantom models)
ROlHL-20548-02 Innervation of the lung (rats, monkeys)
" ROlHL-206 12-02 Chronic animal model of pulmonary
vascular injuiy (dogs)
ROlHL-20652-01 Sites of leakage in pulmonary edema
(dogs)
ROlHL-20690-02 Pulmonary hemodynamics in lung edema
during PEEP (dogs)
ROlHL-20773-02 Surfactant, pulmonary edema, and lung
mechanics (rabbits)
** ROlHL-20878-02 Cellular aspects of lung injury (rats,
rabbits)
** R23HL-21050-02
edema (rabbits)
R23HL-21 168-01 Hypoxemic respiratory failure-Physiologic
evaluation (human, dogs)
R23HL-21199-02 Sound transmission in lung (dog)
** ROlHL-21452-02 Pulmonary capillary filtration in
myocardial ishemia (dogs)
ROlHL-21518-01 Improvement in regional ventilation-
perfusion resolution (human)
R23HL-2194301 Capillary morphology in pulmonary
edema (dogs)
** ROlHL-21948-01 Capillary, tissue volume and lymph flow
in lung edema (sheep, cattle)
ROlHL-22463-02 Pinocytotic vesicles and pulmonary
edema (rats)
** ROlHL-22549-02 Transport across alveolar capillary
membrane (dogs)
ROlHL-22911-01 Mechanism of clearance of lung edema
fluid (dogs)
R23HL-22933-01 Transvascular fluid and protein exchange
in the lung (sheep)
ROlHL-23015-01 Mechanisms of hypo-oncotic pulmonary
edema (human, dogs)
RESPIRATORY DISORDERS, PULMONARY
FIBROSIS AND GRANULOMAS
SEE ALSO METALS POISONING, BERYLLIOSIS
SEE ALSO RESPIRATORY DISORDERS, PNEUMOCONIOSIS
SEE ALSO RESPIRATORY DISORDERS, PNEUMONITIS ALLERGIC
INTERSTITIAL
ROlHL-12650-08 Environmental pathobiology of the lung
(hamsters, rats)
(contd)
Mechanisms of re-expansion pulmonary
RES
PSOH1141S307 0004 Johns Hopkins Lunj Centet
Chronic dis««s«s ot airways Maciophaie onjymes in lunn
inlury. inllammation and repair (labbit)
P50HI 14212 07 Correlated studies ol pulmonary libiosis
■ PbOHl 14212 07 0001 Coiielated studies ol pulmonary
fibrosis Clinical studies core
* PSOHL 14212 07 0004 Correlated studies ol pulmonary
(ibrosis Collagen metabolism in lung tissue and lung
c«Us (human, animal)
* P50HL 1421207 0006 Correlated studies of pulmonary
fibrosis Alveolar macrophage physiology (human, rodents,
rabbits)
* P50HL 14212 07 0007 Correlated studies ot pulmonary
fibrosis Protein metabolism in alveolar macrophages
(rabbits, guinea pigs, human)
* P50HL 14212 07 0011 Correlated studies of pulmonary
fibrosis Pathology core (human, animal)
* P50HL 1421207 0012 Correlated studies of pulmonary
fibrosis Inorganic particulates in tobacco, smoke and
lungs of cigarette smokers (human)
* P50HL 1421207 0013 Correlated studies of pulmonary
fibrosis l^echanism of beryllium pathogenicity in the lung
(human, rabbit, guinea pig)
'* P50HL1421207 0014 Correlated studies ot pulmonary
fibrosis Pulmonary lavage cells, secretions in diffuse
intersititial lung disease (human)
'* P50HL 14212 07 0015 Correlated studies of pulmonary
fibrosis Pulmonary defense mechanisms and fibrotic lung
disease (rodents, rabbits)
'* PSOHL 14212 07 0016 Correlated studies of pulmonary
fibrosis Role of pulmonary alveolar macrophages in
fibrosis (human, rabbit)
" P50HL 14212-07 0017 Correlated studies of pulmonary
fibrosis Biometry core
R01HL1445607 Lung metabolism -Enzymes in the
pulmonary circulation (human, animals)
R01HL1466307 Pulmonary oxygen toxicity in nev»botn
lung (human, mice)
P01HL1498507 0007 Adaptation to hypoxia - Control of
pulmonary circulation, histamine and the sympathetlcs
(animals)
P01HL14985-07 0010 Adaptation to hypoxia - Pulmonary
mast cell (animals)
P01HL1498507 0011 Adaptation to hypoxia -
Prostaglandins in the control of the pulmonary circulation
(animals)
P50HL-15061-07 0004 Response of lung to injury ■
Biochemical abnormalities in connective tissues (rats)
P50HL- 15092-07 0002 Immune and fibrotic response to
occupational environments - Longitudinal study ot
sandblasters silicosis (human)
P50HL-1509207 0008 Immune and fibrotic response to
occupational environments ■ Animal models of asbestosis
(hamsters)
P50HL-1538907 0001 Pulmonary SCOR-Hypersensitivity
pneumonitis • Clinical studies of hypersensitivity
pneumonitis
ROlHL-1559305 Prolonged extracorporeal cardiopulmonary
support (rats, sheep, rabbits)
POlHL-1583206 0005 Chemical-structural predispositions
to lung injury ■ Pulmonary structure and stress-strain
relationships (rats)
POlHL-15832-06 0007 Chemical-structural predispositions
to lung injury - Inactivation of vasoactive agents by the
lung (human, rats. cats, dogs)
P01HL161 18-06 0003 Study of emphysema - Degradation
of collagen and elastin (human, hamsters, mice)
POlHL-161 18-06 0004 Study of emphysema - Metabolic
activity of pulmonary connective tissue (human, hamsters)
ROlHL-16784-03 Lung tissue and water volume (human.
dogs)
P60HL-17292-04 0003 Vermont Lung Center - Subclinical
pulmonary disease in a rural environment (human)
ROlHL-17543-03 0004 liflagnetic tracers for diagnosis of
lung disease - Magnetite retention, distribution, relaxation
rate, viscosity (rabbits)
ROlHL-17551-04 Biosynthesis and metabolism of
procollagen (human, monkeys, mice)
POlHL-17731-04 0006 Physiological basis of pulmonary
disease ■ Ventilation-perfusion ratios (human, dogs)
M POlHL-1781304 Lung disease and the oxygenation of
blood and tissue
** POlHL-17813-04 0001 Lung disease and the oxygenation
of blood and tissue - Diffuse interstitial lung disease -
Pathophysiology (human, dogs)
** POlHL-1 781304 0002 Lung disease and the oxygenation
of blood and tissue - Diffuse interstitial lung disease-
Ultrastructural abnormalities (human)
POlHL-17813-04 0006 Lung disease and the oxygenation
of blood and tissue - Assessment of respiratory muscle
contractile force (human, dogs)
** ROlHL-18606-04 Pathogenesis and measurement of
pulmonaiy edema (human, rabbits, dogs)
** ROlHL-19018-03 Etiologic factors in cryptogenic fibrosing
alveolitis (human)
ROlHL-19225-02 0004 Types and mechanims of
pulmonaiy hypertension • Structural changes in human
pulmonary circulation (human, animals)
R23HL-19584-01 Alveolar macrophage responses to toxic
particle exposure (guinea pigs, human)
** ROlHL-19633-02 Pathogenesis and pharmacology of lung
fibrosis (rats, rabbits)
46/
' R01HM9668 0.1 Biochemistry of lung connective tissue
(rats)
ROIHI 19685 03 Pattiogenesis o( inflammation of the lung
(guinea pigs)
• ROIHI 19711 03 Lymphokines in pulmonary granulomas
(guinea pigs)
1 POIHL 19717 02 Response ot the lung to in|ury
POIHL 19717 02 0002 Response of the lung to injury
Piolyl hydroxylase, lysyl hydioxylase and lung collagen
biosynthesis (rabbits)
POIHL 1971702 0006 Response ol the lung to in|ury
Glycosaminoglycans and proteoglycans of the lung (human.
rats, hamsters)
POIHL 19717 02 0007 Response of the lung to iniury
Cellular level studies of prostaglandin like molecules
(cattle)
• POIHL 19717 02 0008 Response of the lung to in|ury
Experimental models of lung disease
POIHL 1971702 0013 Response of the lung to iniury
Handling of biologically active substances by the diseased
lung (guinea pigs)
" POIHL 19717 02 0019 Response of the lung to injury
Animal model of fibrosing alveolitis (hamsters, guinea
pigs, rabbits)
"* POIHL 19717 02 0020 Response ol the lung to injury
Recording of lung sounds in animal models of disease
(animals)
■' P01HL19717 02 0021 Response of the lung to injury •
Gallium lung scans in fibrosing alveolitis (hamsters)
POIHL- 197 1702 0037 Response of the lung to injury •
Catecholamines, prostaglandins and nucleotides in
pulmonary function (animals)
** POlHL-197 17-02 0038 Response of the lung to injury -
Interstitial lung disease-Clinical, pathologic and
epidemiologic
P01HL19717-02 0041 Response of the lung to injury
Cellular immunity in interstitial lung disease (human)
POlHL-19717-02 0044 Response of the lung to injury ■
Lung sound analysis (human)
POIHL 19717 02 0046 Response of the lung to injury
Bioengineering section
** ROlHL-19720-03 Evaluation of antifibrotic agents in
pulmonary fibrosis (rats)
** ROlHL-19731-03 Collagen in interstitial fibrosis of lung
(human)
** ROlHL-19732 03 Lymphokines in pulmonary
granulomatous inflammation (mice)
ROlHL-19733-03 Absorption of antigen through inflamed
lungs (rabbits)
ROIHL 19746-03 Proliferation and differentiation of
alveolar macrophages (mice, hamsters)
** R01HL-19774-03 Pathogenesis of chronic lung disease
(rats. mice, bacteria)
** ROlHL-19819-03 Mitogen induced interstitial pneumonitis
(rabbits)
** ROlHL-20095-03 Role of lymphokines and monocytes in
lung fibrosis (human, guinea pigs, rats)
** ROlHL-20104-03 Pulmonary granulomatous inflammations
(mice)
ROlHL-20815-02 Validation of indirect tests of small
airways function (human, dogs, ponies)
R23HL-2 11 34-02 Immune function and fibrogenesis in
silicosis (guinea pigs)
R23HL-2 11 99-02 Sound transmission in lung (dog)
** R23HL-2150402 Collagen synthesis in pulmonary fibrosis
cells (human)
" ROlHL-22301-01 Immunogenetics of chronic pulmonary
inflammation (mice)
ROlHL-22302 01 Immune responses in the human lung
(also rabbits, monkeys)
ROlHL-2237101 Vascular changes in lung exposed to
radiation
** ROlHL-22676-01 Pathogenesis in experimental interstitial
pneumonitis (rabbits)
RESPIRATORY DISORDERS, RESPIRATORY
AIRFLOW DISORDERS
SEE ALSO CONGENITAL ABNORMALITIES, RESPIRATORY
DISTRESS SYNDROME
SEE ALSO HYPERSENSITIVITY, RESPIRATORY
HYPERSENSITIVITY, ASTHMA
SEE ALSO RESPIRATORY DISORDERS, BRONCHITIS CHRONIC
AND EMPHYSEMA
SEE ALSO RESPIRATORY DISORDERS, BRONCHOSPASM
SEE ALSO RESPIRATORY DISORDERS, DYSPNEA
SEE ALSO RESPIRATORY DISORDERS, PULMONARY EDEMA
ROlHL-04651-19 Remote stimulation by radio-frequency
transmission (dogs, human)
** POlHL-06285-18 0188 Cardiovascular-respiratory
physiology and biochemistry - Physiology and pharmacology
in regulation of airways-hyperirritability (animals)
POlHL-06285-18 0189 Cardiovascular-respiratory
physiology and biochemistry - Mucociliary clearance (cats,
dogs)
** POlHL-06285-18 0190 Cardiovascular-respiratory
physiology and biochemistry - Maximal (airway) flow
(human, dogs)
** R01HL-08789-11 Respiratory muscles and ventilatory
control in man (and dogs)
POlHL-08805-15 0044 Regulation of ventilation and
pulmonary circulation - Neurochemical interactions in
respiratory control (human, dogs, goats)
RfS
iililalion dnfl
ijiion ol
M
M
POIMI 08805 lb 0045 Ritf"
pulmonary circulation Intof.i
ncuiochcmital lespiralory conliol ■.y.li'ih
POIHI 0889') 14 0015 Tolerance lo leipiraloiy ga'.f. m
health and disease Re^piialory adaptations to increawj
in breathing (human)
ROIHI 11802 10 Cardiovascular surgical retsaich (dogl.
sheep, swinc. cats, monkeys)
ROIHI 11907 08 Mechanisms ol pliy.iological reipontei
to exercise (human, dogs)
ROIHI 12564 09 Control of respiration and blood gases
(human, dog)
ROIHL 13885 08 0005 Cystic fibrosis and pulmonary
disease Evaluation of lobar pulmonary lavace (human)
PSOHL 14153 0/ lohns Hopkins Lung Center Chronic
diseases of airways
P50HL 1415307 0001 Johns Hopkins Lung Center
Chronic diseases of airways Genetic and environmental
factors in chronic pulmonary disease (human)
P50HL 1415307 0010 Johns Hopkins Lung Center
Chronic diseases ol airways Risk factors for airways
obstruction in a rural community (human)
P50HL 14153 07 0012 Johns Hopkins Lung Center
Chronic diseases of airways Aspirin intolerance in
reversible lung disease (human)
P50HL-1415307 0016 Johns Hopkins Lung Center
Chronic diseases of airways Airways defense mechanisms
(dogs)
P50HL-15061 07 0005 Response of lung to injury Airway
smooth muscle in health and disease (dogs, guinea pigs)
P60HL- 15160-07 0015 Center lor sickle cell disease
Lung function abnormalities in sickle cell
hemoglobinopathies (human)
ROIHL 16784 03 Lung tissue and water volume (human,
dogs)
ROIHL 17322 04 Functional characterrstics of smooth
muscle isolated from lung (animals)
POIHL 17417-05 0005 Experimental lung transplantation
Lung transplantation in bilateral emphysema (dogs)
' ROlHL-17768-04 Development ol collateral ventilation
(dogs. Iish. horses)
ROlHL-18632-02 Epidemiologic study ol chronic lung
disease
P50HL-1915502 0002 Pathophysiology ol pulmonary
edema - Non-invasive measurement ol protein turnover in
human lung (also sheep)
P50HL 1915602 Pulmonary SCOR -Chronic diseases ol
airways
P50HL19156 02 0001 Pulmonary SCOR -Chronic diseases
ol airways - Irritability ol airways induced by epithelial
damage in healthy subjects (human)
* P50HL 19156-02 0002 Pulmonary SCOR -Chronic diseases
of airways - Early detection ol emphysema and chronic
airway obstruction (human, dog)
P50HL-19156-02 0003 Pulmonary SCOR -Chronic diseases
of airways - Powdered tantalum to study airway morphology
and mucociliary clearance (human)
P50HL 19156-02 0006 Pulmonary SCOR -Chronic diseases
of airways - Core microscopy laboratory
P50HL-19170-02 Harvard pulmonary SCOR -Chronic
diseases ol the airways
P50HL-19170-02 0001 Harvard pulmonary SCOR -Chronic
diseases ol the airways - Natural history, reversibility of
pulmonary abnormalities in smokers (human)
P50HL-19170-02 0003 Harvard pulmonary SCOR -Chronic
diseases of the airways - Mechanisms of bronchial
reactivity to acute and chronic airway challenge (dog)
P50HL-19170-02 0007 Harvard pulmonary SCOR -Chronic
diseases of the airways Therapy effect on airway
obstruction in acute asthma (human)
P50HL-19170-02 0008 Harvard pulmonary SCOR -Chronic
diseases of the airways - Multiple-transient artificial
coughing (dogs, human)
P50HL-19170-02 0009 Harvard pulmonary SCOR -Chronic
diseases of the airways - Ventilatory muscle training in
chronic obstructive pulmonary disease (human)
POlHL-19717-02 Response of the lung to injury
POlHL-1971702 0028 Response of the lung to injury -
Compensatory grovrth of the lung following pneumonectomy
(rabbits)
POlHL-1971702 0038 Response of the lung to injury -
Interstitial lung disease -Clinical, pathologic and
epidemiologic
ROlHL-1980603 Chemotactic control of airway phagocytes
(human, rabbits)
ROlHL-19975-02 Laryngeal biomechanics in pulmonary
therapy (primates)
ROlHL-20024-03 Therapeutic aerosols-Characteristics and
retention (human, dogs)
ROlHL-20548-02 Innervation of the lung (rats, monkeys)
R23HL 20576-01 Airway turbulence and pulmonary oxygen
exchange
ROlHL-20815-02 Validation of indirect tests of small
airways function (human, dogs, ponies)
R23HL-20968-02 Respiratory failure -Control and muscle
dysfunction (human)
ROlHL-20989-01
(sheep, dogs)
ROlHL-2112602
children
ROlHL-22418-01
function (cats)
Pathophysiology of bronchial asthma
Exercise-induced bronchospasm in
Neural control of cardio-respiratory
(contd)
•Excludes routine methodology OR covers only general projects which preclude
•"Oriented significantly to above subject.
indexing at the specific level.
M Grant has subprojects descnbing specific research aspects.
See Appendix for Investigator's name and grant number
RES
** ROlHL-22528-02 Early risk predictors for chronic
pulmonary disease (human)
** ROlHL-22723-01 The morphologic basis of airflow
obstruction (human)
ROlHL-22844-01 Phrenic nerve pacing-Nonmvasive
diaphragm analysis (human, dogs)
** R23HL-22920-01 Dynamic airway behavior (dogs)
•* NOlHR-32903-11 Pilot study to standardize the
measurement of closing volume' (human)
RESPIRATORY DISORDERS, RESPIRATORY
INSUFFICIENCY (GENERAL)
SEE ALSO RESPIRATORY FUNCTION, HYPOVENTILATION,
RESPIRATORY CENTER DYSFUNCTION
** R01HL-0465M9 Remote stimulation by radio-frequency
transmission (dogs, human)
** ROlHL-08696-15 0020 Orthotopic heart transplantation -
Complete cardiopulmonary transplantation (dogs)
ROlHL-0878911 Respiratory muscles and ventilatory
control in man (and dogs)
POlHL-08805-15 0044 Regulation of ventilation and
pulmonary circulation - Neurochemical interactions in
respiratory control (human, dogs, goats)
** ROlHL-0960911 Lung volume and breathing mechanics
during anesthesia (human)
*' P01HL10342-13 0014 The integrated function of
respiration and circulation ■ Oxygen and carbon monxide
transfer (human, dogs, sheep)
** POIHL 10342-13 0025 The integrated function of
respiration and circulation - Pulmonary gas exchange and
metabolism (human, dogs, sheep)
" ROlHL-12530-10 Emphysema -Respiratory function in
disease (human, dogs, rats)
POIHL 13738-08 0002 Cardiac assist devices and
artificial hearts Total replacement with artificial heart
(calves, sheep, ponies)
POlHL-13738-08 0003 Cardiac assist devices and
artificial hearts - Pathophysiological effects of the artificial
heart (calves)
P50HL-14187-07 0015 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses -
Pathophysiologic responses of pulmonary capillary bed
(dog, human)
P50HL14214-07 0027 Newborn lung center for hyaline
membrane disease Oral-laryngeal chemoreceptors and
respiratory failure in newborns (human, sheep)
P50HL142 14-07 0028 Newborn lung center for hyaline
membrane disease ■ Relationship of trace metals to
respiratory failure (dog. sheep, human)
** P50HL142I407 0030 Newborn lung center for hyaline
membrane disease - Effects of ductal patency -Impedance
cardiography and echocardiography (human)
P50HL142 14-07 0032 Newborn lung center for hyaline
membrane disease Evoked electroencephalographic
potential in infants with HMD (human)
R01HL14693-07 Survival value of physiological responses
to hypoxia (dogs)
*• P01HL14985-07 0004 Adaptation to hypoxia - Control of
breathing in respiratory failure (human, dogs)
P01HL15194-07 0011 Pathophysiology of
cardiopulmonary dysfunction ■ Distribution of ventilation-
Oxygen effects on intrapulmonary shunting (human)
ROlHL-15593-05 Prolonged extracorporeal cardiopulmonary
support (rats, sheep, rabbits)
R01HL15668-06 Extracorporeal respiratory gas exchange-
A new approach (dogs)
ROIHL 15676-06 The role of occult myocardial failure in
human shock (human, dogs)
" R01HL16154-05 Membrane lung perfusion for acute
respiratory failure (sheep, baboons)
ROlHL-16582-05 Artificial lungs (dogs)
ROlHL-16714-05 Endothelial cell communication in
homeostasis (human, mammals)
** P60HL17292-04 0009 Vermont Lung Center - Controlled
clinical trials on a clinical core unit (human)
P60HL-17292-04 0029 Vermont Lung Center ■ Computer-
assisted preoperative evaluation (human)
" R01HL17314 04 Effects of anesthesia and loading on
respiration (human, cats)
** ROlHL-1 7355-04 Pulmonary vascular adjustments in
circulatory collapse (dogs, rats)
R01HL17479-04 Blood storage-Thc production of
cardiotoxic material (dogs, human, swine)
POlHL-1773104 0006 Physiological basis of pulmonary
disease - Ventilation-perfusion ratios (human, dogs)
M POlHL-17813-04 Lung disease and the oxygenation of
blood and tissue
** POlHL-1 7813-04 0006 Lung disease and the oxygenation
of blood and tissue • Assessment of respiratory muscle
contractile force (human, dogs)
** ROlHL-18606-04 Pathogenesis and measurement of
pulmonary edema (human, rabbits, dogs)
P50HL-19170-02 0005 Harvard pulmonary SCOR-Chronic
diseases of the airways Pulmonary toxicology of plastics
intermediates and pyrolysis products (animal)
** R01HL19298-03 Pulmonary hemodynamics (dogs, cats)
" ROlHL-19449-03 Gas exchange in acute respiratory failure
ROlHL-19678-01 Quantification of intrathoracic fluid by
impedance (human, dogs)
ROlHL-19993-02 Optical detection of platelet aggregates
(human, baboons)
ROlHL-2035402 Direct determination of oxygen tension in
the clinical environment (human, dogs)
468
** ROlHL-20366-03 Protein turnover and amino acid
transport by lung (rats)
** ROlHL-2061202 Chronic animal model of pulmonary
vascular injury (dogs)
** ROlHL-2069002 Pulmonary hemodynamics in lung edema
during PEEP (dogs)
** ROlHL-2084702 Respiratory neurochemical control
(human, goats)
** R23HL-20968-02 Respiratory failure -Control and muscle
dysfunction (human)
** R23HL-21 16801 Hypoxemic respiratory failure-Physiologic
evaluation (human, dogs)
R23HL-2140501 Respiratory muscles in regulation of
infant breathing (human)
ROlHL-2144402 Pulmonary mechanics during postnatal
development (human)
ROlHL-21500-02 Performance of respiratory muscles under
stress (dogs)
** ROlHL-21518-01 Improvement in regional ventilation-
perfusion resolution (human)
** ROlHL-22022 01 Respiratory muscle dysfunction in
respiratory failure (human)
** ROlHL-22259-01 Modification of susceptibility to oxygen
poisoning (rats)
** R13HL-22525-01 International symposium on the
diaphragm (Virginia)
** ROlHL-22552-02 Abnormal alveolar permeability and lung
disease (sheep)
** NOlHR-62942-04 Nocturnal oxygen therapy in chronic
hypoxic lung disease (humam)
** NOlHR-62943 05 Nocturnal oxygen therapy in chronic
hypoxic lung disease (human)
** NOlHR-62944-04 Nocturnal oxygen therapy in chronic
hypoxic lung disease (human)
** NOlHR-62945-04 Nocturnal oxygen therapy in chronic
hypoxic lung disease (human)
** NOlHR-62946-04 Nocturnal oxygen therapy in chronic
hypoxic lung disease (human)
** NOlHR-62947-04 Nocturnal oxygen therapy in chronic
hypoxic lung disease (human)
RESPIRATORY DISORDERS, RESPIRATORY
INSUFFICIENCY, SHOCK LUNG
** POlHL-10342-13 0025 The integrated function of
respiration and circulation ■ Pulmonary gas exchange and
metabolism (human, dogs, sheep)
** ROlHL-12530-10 Emphysema-Respiratory function in
disease (human, dogs, rats)
ROlHL-1317210 Post-trauma lung mechanics and fluid
exchange (human, dogs, monkeys)
ROlHL-1359607 Clearance of plasma proteins from
alveoli
P50HL-14187-07 0012 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses ■ Vasoactive
mediators in pulmonary disease (human, animal)
P50HL-14187-07 0014 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses - Metabolism
and actions of vasoactive peptides in lung (human,
mammals)
POlHL-14388-07 0220 Regulation of the circulation in
pathological states • Pharmacology of the coronary
circulation In man
POlHL-14985-07 0003 Adaptation to hypoxia - Hypoxia
and oxygen transport (human, dogs)
POlHL-14985-07 0007 Adaptation to hypoxia ■ Control of
pulmonary circulation, histamine and the sympathetics
(animals)
POlHL-14985-07 0010 Adaptation to hypoxia - Pulmonary
mast cell (animals)
POlHL-14985-07 0011 Adaptation to hypoxia ■
Prostaglandins in the control of the pulmonary circulation
(animals)
** POlHL-16769-05 0002 Pathobiologic and host defense
reactions in the lung - Pathogenesis of complement
dependent injury to the lungs (rabbits)
ROlHL-17479-04 Blood storage-The production of
cardiotoxic material (dogs, human, swine)
" POIHL 17812-04 0007 Thrombosis and plasma proteins ■
Blood components-Response to endotoxin (dogs, baboons)
** ROlHL-18762-03 Post-traumatic pulmonary insufficiency
(dogs)
P50HL-1915502 0004 Pathophysiology of pulmonary
edema - Physical and chemical effects of multiple
pulmonary emboh (sheep)
P50HL-19187-02 0009 Pediatric pulmonary SCOR-Hyaline
membrane disease - Noninvasive measurement and
monitoring of arterial oxygen tension (dogs, sheep)
" R01HL19225-02 0004 Types and mechanims of
pulmonary hypertension - Structural changes in human
pulmonary circulation (human, animals)
ROlHL-19721-03 Lung inflammation-Lysosomal proteases
and liposomes (human, rabbits)
** R01HL1972503 Complement induced pulmonary injury
(dogs, rabbits, sheep)
'* R23HL-22346-01 Hematological injury and pulmonary
dysfunction (human, mammals)
'* ROlHL-22641-01 Ventilation, perfusion, and systemic
arterial reflexes (dogs)
ROlHL-23981-01 Acute alveolar injury (dogs)
RES
RESPIRATORY DISORDERS, RESPIRATORY
SYSTEM TOXINS
POlHL-1034213 0011 The integrated function of
respiration and circulation ■ Control of respiration 1-
Peripheral chemoreceptor studies (cats)
P50HL-14212-07 0006 Correlated studies of pulmonary
fibrosis ■ Alveolar macrophage physiology (human, rodents,
rabbits)
** P50HL14212-07 0013 Correlated studies of pulmonary
fibrosis ■ Mechanism of beryllium pathogenicity in the lung
(human, rabbit, guinea pig)
** P50HL-1506107 0012 Response of lung to injury ■
Hyperbaric oxygen, carbon monoxide, and ozone or peroxide
toxicity (rats)
** P50HL- 15389-07 0009 Pulmonary SCOR-Hypersensitivity
pneumonitis - Clinical studies-Pulmonary mycotoxicosis
** P50HL-1538907 0013 Pulmonary SCOR-Hypersensitivity
pneumonitis - Animal model-Pulmonary mycotoxicosis
(rabbit, guinea pig)
** ROlHL-16029-05 Bio-organic chemistry of ozone, nitrogen
dioxide and tobacco smoke
POlHL-161 18-06 0004 Study of emphysema - Metabolic
activity of pulmonary connective tissue (human, hamsters)
** ROlHL-16674-05 Airborne metals and lung permeability
(bullfrogs, rats)
R01HL1802803 Absorption of nonvolatile compounds
from the lung
" P50HL-19170-02 0005 Harvard pulmonary SCOR-Chronic
diseases of the airways ■ Pulmonary toxicology of plastics
intermediates and pyrolysis products (animal)
** R23HL-1958401 Alveolar macrophage responses to toxic
particle exposure (guinea pigs, human)
" ROIHL 2100802 Effect of pollutants on organotypic lung
cultures (rats)
ROlHL-21009-02
culture (rats)
ROlHL-2252001
Effects of air pollutants on lung cells in
Pulmonary vascular response to group 8
•Excludes routine methodology OR covers only general projects which preclude indexing
""Onented significantly to above subject
at the specific level.
M Grant has subprojects describing specific research aspects
See Appendix for investigators name and grant number.
Streptococci (human, mammals)
RESPIRATORY DISORDERS CHEMOTHERAPY
SEE ALSO RESPIRATORY DRUGS. BRONCHOCONSTRICTORS
SEE ALSO RESPIRATORY DRUGS, BRONCHODILATORS
SEE ALSO RESPIRATORY DRUGS, EXPECTORANTS AND
MUCOLYTICS
SEE ALSO RESPIRATORY SYSTEM PHARMACOLOGY
POlHL-06285-18 0181 Cardiovascular-respiratory
physiology and biochemistry - Regulation of respiration-
Role of vagus nerve (dogs)
POlHL-0637017 0013 Cardiopulmonary and renal
pathology research center - Morphologic analysis of
vascular prosthesis (human, dogs)
POlHL-10342-13 0028 The integrated function of
respiration and circulation • Mediator release,
hemodynamics and respiratory function in anaphylaxis
(dogs)
ROlHL-1253010 Emphysema -Respiratory function in
disease (human, dogs, rats)
ROlHL-14102-07 Human physiology at 5360 meters-
Mountain environment
ROlHL-1469206 Alpha 1 antitrypsin deficiency and
pulmonary disease (human)
ROlHL-14700-05 Humoral and lung protease-antiprotease
role in obstructive disease (human)
ROlHL-14865-07 Biochemical studies on the pathogenesis
of emphysema (human, rats)
POlHL-14985-07 0002 Adaptation to hypoxia ■ Oxygen
transport in man at high altitude
POlHL-14985-07 0013 Adaptation to hypoxia - Chronic
mountain sickness (men)
P01HL14985-07 0014 Adaptation to hypoxia - High
altitude pulmonary edema (human, rats, dogs)
P50HL-15389-07 0001 Pulmonary SCOR-Hypersensitivity
pneumonitis ■ Clinical studies of hypersensitivity
pneumonitis
ROlHL-1552605 Respiratory mechanics in children
R01HL-I5580-06 Humoral control of pulmonary and
systemic circulation (animals)
ROlHL-1646305 Localization of airways obstruction and
responses
R01HL16916-04 0001 The role of albumins in lung water
accumulation ■ Capillary permeability (dogs, human)
* P60HL- 17292-04 0009 Vermont Lung Center - Controlled
clinical trials on a clinical core unit (human)
P01HL-I7382-05 0001 Chemical mediators of acute
pulmonary disorders - Chemical mediators and respiratory
mechanics in humans
P01HL17382-05 0002 Chemical mediators of acute
pulmonary disorders - Chemical mediators and respiratory
mechanics in guinea pigs
POlHL-17731-04 0006 Physiological basis of pulmonary
disease - Ventilation-perfusion ratios (human, dogs)
ROlHL-17776-04 Pulmonary mucus transport in
obstructive lung diseases (human)
POlHL-17813-04 0001 Lung disease and the oxygenation
of blood and tissue - Diffuse interstitial lung disease-
Pathophysiology (human, dogs)
ROlHL-17873-04 Pathophysiology of exercise-induced
asthma (human)
R01HL-18308-03 Comprehensive studies of mucociliary
transport (dogs)
(contd)
RES
•• P50HL 191/(10.' 1)00/ Harvard pulmonaiy SCOR Chronic
diseases ol the airways Therapy ellecl on airway
obstruction in acute asthma (human)
PMHl 1918502 0007 Pulmonary SCOR Neonatal
respiratory distress syndromes Sodium bicarbonate and
albumin in resuscrtation ol preterm infants (human)
ROIHI 19633 02 Pathogenesis and pharmacology ol lung
fibrosis (rats, rabbits)
M POIHL 19717 02 Response of the lung to inlury
POIHL 1971702 0038 Response ol the lung to in)ury
Interstitial lung disease-Clinical, pathologic and
epidemiologic
POIHL 19717 02 0039 Response of the lung to iniury •
Lung scanning in alveolitis and asbestolic interstitial
pneumonia (human, animal)
** POIHL 19717 02 0040 Response of the lung to inlury
Immunosuppressive drugs in usual interstitial pneumonia
(human)
** ROIHL 19720-03 Evaluation of antifibrotic agents in
pulmonary fibrosis (rats)
ROIHL 20783 02 Airway reactivity -Badrenoceptors and
prostaglandins (guinea pigs)
** ROIHL 20963 01 Experimental lung abscess (rabbits)
R23HL-20968 02 Respiratory failure -Control and muscle
dysfunction (human)
ROIHL 21444 02 Pulmonary mechanics during postnatal
development (human)
ROlHL-22021-01 Asthma in families - Behavior analysis of
family interaction pattern
R01HL2202601 Endogenous prostaglandins m asthma
ROlHL-22065-01 Intractability, medication, and coping
styles in asthma (human)
•* R23HL-22895-01 Smoke inhalation-Biochemical and
cellular responses (rabbits, bacteria)
NOlHR-62934-02 Evaluate continuing education in
pulmonary medicine
RESPIRATORY DISORDERS CONGENITAL
SEE CONGENITAL ABNORMALITIES, RESPIRATORY (GENERAL)
RESPIRATORY DISORDERS DIAGNOSIS*
SEE ALSO RESPIRATORY VISUALIZATION*
** POlHL-04664-18 0002 Cardiovascular and lung dynamics
- X-ray cross section imaging of organs (dogs)
♦* POlHL-06285-18 0146 Cardiovascular-respiratory
physiology and biochemistry ■ Pathogenesis and detection
of hypoxic pulmonary edema (human, animals)
** POlHL-06370-17 0013 Cardiopulmonary and renal
pathology research center - Morphologic analysis of
vascular prosthesis (human, dogs)
** POlHL-06370-17 0017 Cardiopulmonary and renal
pathology research center - Detection of pulmonary lesions -
Radiologic pathologic correlation
POlHL-08805-15 0045 Regulation of ventilation and
pulmonary circulation - Integrated description of
neurochemical respiratory control system
ROlHL-09609-11 Lung volume and breathing mechanics
during anesthesia (human)
** ROIHL- 10009- 13 Regional lung function in man
POlHL-1034213 0025 The integrated function of
respiration and circulation - Pulmonary gas exchange and
metabolism (human, dogs, sheep)
ROlHL-12833-09 Genetic and environmental influences on
lung disease (human)
** ROlHL-13824-06 Defense mechanisms in pathogenesis of
emphysema (human, dogs)
ROlHL-13885-08 0007 Cystic fibrosis and pulmonary
disease - Alveolar macrophage defense mechanism
(human, rabbits)
ROlHL-13885-08 0009 Cystic fibrosis and pulmonary
disease - Respiratory mucus glycoproteins (human, rabbits)
** ROlHL-13885-08 9001 Cystic fibrosis and pulmonary
disease - Pulmonary function core facility (infants,
children)
" ROlHL-13885-08 9002 Cystic fibrosis and pulmonary
disease - Computer core facility (human)
ROlHL-13885-08 9003 Cystic fibrosis and pulmonary
disease - Fiberoptic bronchoscopy core facility (human,
dogs, sheep)
P50HL-14136-07 0003 Pulmonary SCOR-Airways
obstructive diseases - Acute pediatric respiratory disease
and COLD
♦* P50HL-14136-07 0017 Pulmonary SCOR-Airways
obstructive diseases ■ Pediatric airways obstructive disease
(human)
** P50HL-14136-07 9002 Pulmonary SCOR-Alrways
obstructive diseases - Physiology core (human, animal)
P50HL14136-07 9005 Pulmonary SCOR-Airways
obstructive diseases - Clinical core
** P50HL1413607 9006 Pulmonary SCOR-Airways
obstructive diseases - Pediatric lung function core
** P50HL-14153-07 0018 Johns Hopkins Lung Center-
Chronic diseases of airways - Pulmonary function core
P50HL-14212-07 0001 Correlated studies of pulmonary
fibrosis - Clinical studies core
P50HL-14212-07 0004 Correlated studies of pulmonary
fibrosis - Collagen metabolism in lung tissue and lung
cells (human, animal)
** P50HL-14214-07 0012 Newborn lung center for hyaline
membrane disease ■ Pulmonary status of children who had
HMD as infants
469
P50HI 14214 0/ 0030 Newborn lung ccnlci tor hyaline
membrane disease Effects of ductal patency Impedance
cardiography and echocardiography (human)
•* POIHL 145800/ 0005 Program project in respiratory
mechanics Development and evaluation ol tests of
pulmonary functron (human)
P50HL 15092 07 0002 Immune and fibfotic response to
occupational environments Longitudinal study of
sandblaslers silicosis (human)
POIHL 15194 07 0024 Pathophysiology of
cardiopulmonary dysfunction Distribution ol ventilation
Airflow limitation in COLD (human)
•• P50HL 15389 07 0001 Pulmonary SCOR Hypersensrtivity
pneumonrtis Clinical studies of hypersensitivity
pneumonitis
P50HL 15389 07 0008 Pulmonary SCOR -Hypersensitivity
pneumonitis Milwaukee patient study Hypersensitivity
pneumonitis
** P50HL 15389-07 0016 Pulmonary SCOR -Hypersensitivity
pneumonitis Pulmonary physiology core (human)
POIHL 15832-06 0007 Chemical structural predispositions
to lung iniury Inactivation ol vasoactive agents by the
lung (human, rats, cats, dogs)
♦* ROlHL-16325-03 Breathing patterns in man
POlHL-16748-05 0006 Cellular and immunological basis
of pulmonary diseases - Sarcoidosis-Studies with bronchial
lavage (human)
ROlHL-169 16-04 0001 The role of albumins in lung water
accumulation - Capillary permeability (dogs, human)
ROlHL-1691604 0002 The role of albumins in lung water
accumulation - Lung water balance -Forces, models and
albumin concentrations (rabbits, dogs)
P60HL- 17292-04 0005 Vermont Lung Center - Mineral
pneumoconioses -Pathogenesis and pathology (human)
** P60HL-17292-04 0031 Vermont Lung Center - Regional
respiratory computer network
ROlHL-17355-04 Pulmonary vascular adjustments in
circulatory collapse (dogs, rats)
M POlHL-17417-05 Experimental lung transplantation
•• POlHL-17417-05 0003 Experimental lung transplantation
- Methods for detecting lung allograft rejection (dogs)
M ROlHL-17543-03 Magnetic tracers for diagnosis of lung
disease
** ROlHL-17543-03 0001 Magnetic tracers for diagnosis of
lung disease - Chronic, interstitial lung disease (human,
rabbits)
** ROlHL-17543-03 0002 Magnetic tracers for diagnosis of
lung disease - Magnetite as an index of asbestos exposure
(human)
** ROlHL-17543-03 0003 Magnetic tracers for diagnosis of
lung disease - Occupationally accumulated magnetite for
diagnosis of lung disease (human)
" ROlHL-17543-03 0004 Magnetic tracers for diagnosis of
lung disease ■ Magnetite retention, distribution, relaxation
rate, viscosity (rabbits)
** ROlHL-17826-04 Oxygen delivery to tissue (rat, dog)
** ROlHL-18606-04 Pathogenesis and measurement of
pulmonary edema (human, rabbits, dogs)
R01HL18632-02 Epidemiologic study of chronic lung
disease
ROlHL-18968-03 Computer technology for transaxial
tomography
** R01HL-190 18-03 Etiologic factors in cryptogenic fibrosing
alveolitis (human)
** P50HL-19155-02 0001 Pathophysiology of pulmonary
edema - Pulmonary edema study unit (human, dog)
P50HL-191 70-02 0010 Harvard pulmonary SCOR -Chronic
diseases of the ain«ays - Computer Core
P50HL-1917102 0003 Pulmonary SCOR -Lung injury by
childhood infections - Natural history, host defense defects-
Children with chronic pulmonary disease
P50HL-19171-02 0005 Pulmonary SCOR-Lung injury by
childhood infections ■ Chronic respiratory disease of
children in North Carolina
** P50HL19185-02 0006 Pulmonary SCOR-Nconatal
respiratory distress syndromes - Evaluation of risk factors
in neonatal respiratory distress (human, sheep)
** P50HL-19190-02 0009 Pulmonary SCOR-Pathophysiology,
management of IRDS - Developing non-invasive neonatal
pulmonary monitoring systems (rabbit, human)
ROlHL-19352-03 Respiratory heat and water loss in
neonates
ROlHL-19449-03 Gas exchange in acute respiratory failure
** R23HL-19619-01 Sem and x ray analysis in human
pulmonary pathology
** ROlHL-19678-01 Quantification of intrathoracic fluid by
impedance (human, dogs)
M POlHL-197 17-02 Response of the lung to injury
** POlHL-19717-02 0021 Response of the lung to injury -
Gallium lung scans in fibrosing alveolitis (hamsters)
** POlHL-19717-02 0038 Response of the lung to injury -
Interstitial lung disease-Clinical, pathologic and
epidemiologic
** POlHL-197 17-02 0039 Response of the lung to injury -
Lung scanning in alveolitis and asbestolic interstitial
pneumonia (human, animal)
POlHL-197 17-02 0040 Response of the lung to injury -
Immunosuppressive drugs in usual interstitial pneumonia
(human)
POlHL-197 17-02 0043 Response of the lung to injury -
Asbestosis as a model of usual interstitial pneumonia
(human)
RES
•• I'OIIII \'ll\l i>/ OU'l't H' 1 " ' I ' ' " ■' '" '"I"''
lung iound analy.i". Ihuin,"/
•• POIIII 19/17 02 0045 hi-.p'-ii.t '.I H' I'^-i 'o miury
Ultrasound studies (human, hdm-.leri)
POIHI 19/1/02 0046 Re',pon« of the lung lo injury
Bioengineering section
*• ROIHI 19/25 03 Complement induced pulmonary injury
(dogs, rabbits, sheep)
'* ROIHI 2011002 Microwave method-, of lung water
measurement (dogs, phantom models)
ROIHL 20607 02 Tissue analysis by mass spectrometer
(dogs)
•* ROIHL 20815 02 Valrdation of indirect tests of small
airways function (human, dogs, ponies)
•• ROIHL 20847 02 Respiratory neurochemical control
(human, goats)
•* R01HL2115602 Anlrtrypsin and other causes ol chronic
lung disease
•* R23HL 2116801 Hypoxemic respiratory failure Physiologic
evaluation (human, dogs)
** R23HL 21199 02 Sound transmission in lung (dog)
ROIHL 21518 01 Improvement in regional ventilation-
perlusion resolution (human)
** ROlHL-21548-01 Pathogenesis of pulmonary
thromboembolic disease (human, mammals)
** POlHL-21584-02 0006 Respiratory mechanics in normal
and abnormal states - Respiratory mechanics in health and
disease (human, pigs)
ROIHL 22026-01 Endogenous prostaglandins in asthma
** ROlHL-22302-01 Immune responses m the human lung
(also rabbits, monkeys)
** ROlHL-2272301 The morphologic basis of airflow
obstruction (human)
** ROlHL-22844-01 Phrenic nerve pacing Noninvasive
diaphragm analysis (human, dogs)
** ROlHL-22910-01 Control of breathing pattern in health
and disease (human, animals)
** ROlHL-22976-01 Nonuniform ventilation and diffusing
capacity (human)
ROlHL-23981-01 Acute alveolar injury (dogs)
NOlHR-62934-02 Evaluate continuing education in
pulmonary medicine
RESPIRATORY DISORDERS DIAGNOSIS,
PNEUMOGRAPH*
POlHL-06285-18 0188 Cardiovascular-respiratory
physiology and biochemistry - Physiology and pharmacology
in regulation of airways-hyperirritability (animals)
RESPIRATORY DISORDERS DIAGNOSIS,
RESPIRATORY AIRFLOW MEASUREMENTS*
POlHL-06285-18 0181 Cardiovascular-respiratory
physiology and biochemistry - Regulation of respiration-
Role of vagus nerve (dogs)
** POlHL-06285-18 0190 Cardiovascular-respiratory
physiology and biochemistry - Maximal (airway) flow
(human, dogs)
ROlHL-07575-15 Analysis of time-coherent cardiovascular
data
POlHL-08899-14 0057 Tolerance to respiratory gases in
health and disease - Studies of intermittent exposure in
man
R01HL10009-13 Regional lung function in man
ROIHLI 1907-08 Mechanisms of physiological responses
to exercise (human, dogs)
P50HL-14136-07 0017 Pulmonary SCOR-Airways
obstructive diseases - Pediatric airways obstructive disease
(human)
P50HL-14136-07 9002
obstructive diseases
POlHL-14414-07 0003
Pulmonary SCOR-Airways
Physiology core (human, animal)
Environmental influences on
cardiorespiratory and cellular functions - Exposure to
abnormal gaseous environments (human, dogs, rabbits)
POlHL-14580-07 0002 Program project in respiratory
mechanics - Airway aerodynamics (human, dogs)
POlHL-14580-07 0005 Program project in respiratory
mechanics - Development and evaluation of tests of
pulmonary function (human)
POlHL-14985-07 0004 Adaptation to hypoxia - Control of
breathing in respiratory failure (human, dogs)
POlHL-14985-07 0005 Adaptation to hypoxia - Control
mechanisms in the pulmonary microcirculation (animals)
POlHL-15194-07 0024 Pathophysiology of
cardiopulmonary dysfunction - Distribution of ventilation-
Airflow limitation in COLD (human)
ROlHL-15526-05 Respiratory mechanics in children
ROlHL-15659-05 Dynamic isolation studies of control of
respiration (human)
ROlHL-16325-03 Breathing patterns in man
Localization of airways obstruction and
Lung tissue and water volume (human,
Control of ventilation in health and
•Excludes routine methodology OR covers only general projects which preclude
"Oriented significantly to above subject.
indexing at the specific level.
M Grant has subprojects describing si
See Appendix for investigator's name
ROlHL-16463-05
responses
" ROlHL-16784-03
dogs)
M POlHL-16878-05
disease
** POlHL-16878-05 0001 Control of ventilation in health
and disease - Ability of asthmatics to detect added
resistive and elastic loads
POlHL-16878-05 0003 Control of ventilation in health
and disease - Brain stem respiratory neurons in response
mechanical/chemical loading (animal)
(contd)
ipecific research aspects,
and grant number.
RES
POlHL-17382-05 0001 Chemical mediators of acute
pulmonaiy disorders - Chemical mediators and respiratory
mechanics in humans
M P01HH7731-04 Physiological basis of pulmonary disease
•* POlHL-1773104 0002 Physiological basis of pulmonary
disease - Biomechanics of the lung (frogs, cats)
ROlHL-17768-04 Development of collateral ventilation
(dogs, fish, horses)
R01HL17873-04 Pathophysiology of exercise-induced
asthma (human)
R01HL1807004 Regulation of intrapulmonary airways
and vessels (human, animals)
** R01HL1911803 Measurement of airways mechanics
(human, dog)
** P50HL-19156-02 0002 Pulmonary SCOR-Chronic diseases
of airvfays • Early detection of emphysema and chronic
airvyay obstruction (human, dog)
ROlHL-19225-02 0003 Types and mechanims of
pulmonary hypertension ■ Cardiopulmonary function In pigs
and rats
** R01HL1935203 Respiratory heat and water loss in
neonates
POIHL 1971702 0008 Response of the lung to injury -
Experimental models of lung disease
** ROlHL-19827-02 Role of the upper airways in the control
of breathing (human, cats, dogs)
** ROlHL-2034702 Bolus-response measurement of lung
function (human)
R23HL-2057601 Airway turbulence and pulmonary oxygen
exchange
** ROlHL-20815-02 Validation of indirect tests of small
airways function (human, dogs, ponies)
ROlHL-20847-02 Respiratory neurochemical control
(human, goats)
POlHL-2099402 0008 Dynamics of neutrophil elastase in
the lung - Structure-function correlation in experimental
emphysema (human, dogs)
ROlHL-21500-02 Performance of respiratory muscles under
stress (dogs)
** POlHL-2 1584-02 0006 Respiratory mechanics in normal
and abnormal states - Respiratory mechanics in health and
disease (human, pigs)
ROlHL-22415-01 Mechanisms responsible for disease
severity in asthma (human)
ROlHL-22723-01 The morphologic basis of airflow
obstruction (human)
•* R23HL-22920-01 Dynamic airway behavior (dogs)
" NOlHR-32900-09 Pilot study to standardize the
measurement of 'closing volume' (human)
" NOlHR-3290207 Pilot study to standardize the
measurement of closing volume (human)
** NOlHR-32903-11 Pilot study to standardize the
measurement of 'closing volume' (human)
** NOlHR-62901-04 Measure pulmonary function in infants
and children (also dogs, rabbits)
RESPIRATORY DISORDERS DIAGNOSIS,
RESPIRATORY AIRFLOW MEASUREMENTS,
ULTRASONIC*
R01HL19019-03 Accurate transcutaneous Doppler blood
flow monitoring
" ROlHL-22413-01 Enhanced detection of bubbles in
Doppler flow signals (human)
** ROlHL-22517-01 Engineering development of an ultrasonic
ventilometer (human)
ROlHL-22852-01 Diagnostic techniques in venous
thromboembolism (human)
RESPIRATORY DISORDERS DIAGNOSIS,
SPIROMETRY*
ROlHL-13885-08 9001 Cystic fibrosis and pulmonary
disease - Pulmonary function core facility (infants,
children)
R01HL13885-08 9002 Cystic fibrosis and pulmonary
disease ■ Computer cor" facility (human)
** P5OHL-14153-07 0010 Johns Hopkins Lung Center-
Chronic diseases of airways - Risk factors for airways
obstruction in a rural community (human)
P01HL1458007 0001 Program project In respiratory
mechanics • Micromechanics of the lung (dogs, rats)
P60HL-1 7292-04 0031 Vermont Lung Center - Regional
respiratory computer network
ROlHL-22528-02 Early risk predictors for chronic
pulmonary disease (human)
RESPIRATORY DISORDERS EPIDEMIOLOGY
ROlHL-13885-08 9002 Cystic fibrosis and pulmonary
disease - Computer core facility (human)
P50HL-1413607 Pulmonary SCOR -Airways obstructive
diseases
Pulmonary SCOR-Airways
Acute pediatric respiratory disease
M
P50HL-14136-07 0003
obstructive diseases <
and COLO
P50HL-14136-07 0005
obstructive diseases -
Pulmonary SCOR-Airways
Radiographic studies of airways
obstructive disease (human)
P50HL-14136-07 0009 Pulmonary SCOR-Airways
obstructive diseases ■ Tuicon epidemiological study of
airways obitructlva distiie (human)
P50HL-14136-07 0016 Pulmoniry SCOR-Airways
obstructiv* dliiiHi ■ Envlronmintil fictori In alrwtys
obstructlvi dIstiMi (humin)
P50HL-14136-07 0017
obstructive diseases
(human)
P50HL-14136-07 9001
obstructive diseases
P50HL-14136-07 9005
obstructive diseases
P50HL-14136-07 9006
obstructive diseases -
P50HL-14 153-07 0001
470
Pulmonary SCOR-Airways
Pediatric airways obstructive disease
Pulmonary SCOR-Airways
Biometrics core
Pulmonary SCOR-Airways
Clinical core
Pulmonary SCOR-Airways
Pediatric lung function core
Johns Hopkins Lung Center-
Chronic diseases of airways - Genetic and environmental
factors In chronic pulmonary disease (human)
** P50HL-14153-07 0010 Johns Hopkins Lung Center-
Chronic diseases of airways ■ Risk factors for airways
obstruction in a rural community (human)
** P50HL-141 53-07 0011 Johns Hopkins Lung Center-
Chronic diseases of airways - Allergy, airways reactivity
and asthma in human ragweed allergy
P50HL-142 12-07 0001 Correlated studies of pulmonary
fibrosis - Clinical studies core
R01HL14692-06 Alpha 1 antitrypsin deficiency and
pulmonary disease (human)
M P50HL-15092-07 Immune and fibrotic response to
occupational environments
P50HL- 15092-07 0001 Immune and fibrotic response to
occupational environments - X-ray diffraction study-Dust
exposure in asbestos cement products manufacturing
** P50HL-15092-07 0002 Immune and fibrotic response to
occupational environments - Longitudinal study of
sandblasters silicosis (human)
P50HL-1509207 0010 Immune and fibrotic response to
occupational environments - Characterization of toluene
diisocyanate in industrial environments
** P50HL-15092-07 0011 Immune and fibrotic response to
occupational environments - Respiratory and immunologic
responses in coffee plant workers
** P50HL-1 5092-07 0012 Immune and fibrotic response to
occupational environments - Longitudinal evaluation of
workers exposed to cotton dust
** P50HL- 15092-07 0013 Immune and fibrotic response to
occupational environments - Epidemiology core resource
** P50HL-15389-07 0001 Pulmonary SCOR -Hypersensitivity
pneumonitis - Clinical studies of hypersensitivity
pneumonitis
P50HL-15389-07 0009 Pulmonary SCOR -Hypersensitivity
pneumonitis - Clinical studies -Pulmonary mycotoxicosis
P50HL-15389-07 0010 Pulmonary SCOR-Hypersensitivity
pneumonitis - Clinical study-Pulmonary lesions due to non-
invasive aspergillosis
** ROlHL-15614-04 Heredity and oxygen-Effects on health of
heart-lungs (South America)
*• P60HL- 172 92-04 0003 Vermont Lung Center - Subclinical
pulmonary disease in a rural environment (human)
** P60HL-17292-04 0005 Vermont Lung Center - Mineral
pneumoconioses-Pathogenesis and pathology (human)
P60HL-17292-04 0023 Vermont Lung Center - Health
information resources
" ROlHL-18632-02 Epidemiologic study of chronic lung
disease
ROlHL-190 18-03 Etiologic factors In cryptogenic fibrosing
alveolitis (human)
P50HL-191 70-02 0001 Harvard pulmonary SCOR-Chronic
diseases of the airways - Natural history, reversibility of
pulmonary abnormalities in smokers (human)
** P50HL-191 71-02 0001 Pulmonary SCOR-Lung injury by
childhood infections - Longitudinal study-Respiratoiy
infections and lung grovrth in normal children
P50HL-191 71-02 0004 Pulmonary SCOR-Lung Injury by
childhood infections - Long-term effects of respiratory
Infections in early childhood
** P50HL-191 71-02 0005 Pulmonary SCOR -Lung injury by
childhood infections - Chronic respiratory disease of
children in North Carolina
P50HL-191 71-02 0011 Pulmonaiy SCOR-Lung injury by
childhood infections - Clinical support core
** P50HL-191 87-02 0012 Pediatric pulmonary SCOR-Hyaline
membrane disease - Resource requirements, economic
consequence of HMO and recurrent apnea
R23HL-196 19-01 Sem and x ray analysis in human
pulmonary pathology
" POlHL-197 17-02 0038 Response of the lung to injury -
Interstitial lung disease-Clinical, pathologic and
epidemiologic
'* POlHL-19717-02 0043 Response of the lung to injury ■
Asbestosis as a model of usual interstitial pneumonia
(human)
ROlHL-19839-09 Factors in youth predisposing to chronic
diseases (former college students)
'* ROlHL-2 13 52-02 Community studies of obstructive lung
disease (human)
'* ROlHL-22472-01 Smoking risk-factor reduction-
Maintenance strategies (human)
■* ROlHL-22528-02 Early risk predictors for chronic
pulmonary disease (human)
ROlHL-23631-01 Immunogenetic factors In allergic
respiratory diseases (human)
'* NOlHR-32900-09 Pilot study to standardize the
measurement of 'closing volume' (human)
NOlHR-32902-07 Pilot study to standardiw the
meisurement of closing volume (human)
NOlHR-32903-11 Pilot study to standardize the
measurement of 'closing volume' (human)
*E«cludM rwtln* methodology OR covers only general prajacts which preclude indexing
**OrlentMt ilgnlflcantly to (bovt subject.
itthe specific level.
M Grant has subprojects describing specific reMarch aspects.
See Appendix for Investigator's name and grant number.
RES
NOlHR-62935-02 Histocompatibility antigens-Evolution of
respiratory hypersensitivity (human)
RESPIRATORY DISTRESS SYNDROME
SEE CONGENITAL ABNORMALITIES. RESPIRATORY DISTRESS
SYNDROME
RESPIRATORY DRUGS,
BRONCHOCONSTRICTORS
POlHL-0628518 0181 Cardiovascular-respiratory
physiology and biochemistry - Regulation of respiration-
Role of vagus nerve (dogs)
** POlHL-06285-18 0188 Cardiovascular-respiratory
physiology and biochemistry - Physiology and pharmacology
in regulation of airways-hyperirritability (animals)
POlHL-06664-17 0043 Cardiopulmonary function in
remediable vascular disease - Alveolar hypoxic
vasoconstriction-Control and clinical significance (dog,
human)
POlHL-08805-15 0048 Regulation of ventilation and
pulmonary circulation - Permeability of alveolo-Capillary
membrane in normal pulmonary hypertensive lung
ROlHL-10009-13 Regional lung function in man
P50HL1415307 0011 Johns Hopkins Lung Center-
Chronic diseases of airways - Allergy, airways reactivity
and asthma in human ragweed allergy
ROlHL-16463-05 Localization of airways obstruction and
responses
POlHL-1 7382-05 0001 Chemical mediators of acute
pulmonary disorders - Chemical mediators and respiratory
mechanics in humans
P50HL-191 56-02 0005 Pulmonary SCOR-Chronic diseases
of airways - Vagal receptors in the airway-Epithelial injury
and antigen (dog. cat. rabbit)
ROlHL-20783-02 Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
ROlHL-22026-01 Endogenous prostaglandins in asthma
RESPIRATORY DRUGS, BRONCHODILATORS
POlHL-06285-18 0181 Cardiovascular-respiratory
physiology and biochemistry - Regulation of respiration-
Role of vagus nerve (dogs)
POlHL-10342-13 0028 The integrated function of
respiration and circulation - Mediator release,
hemodynamics and respiratory function in anaphylaxis
(dogs)
ROlHL-1253010 Emphysema-Respiratory function in
disease (human, dogs, rats)
P50HL-14 187-07 0012 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses - Vasoactive
mediators in pulmonary disease (human, animal)
POlHL-14580-07 0001 Program project in respiratory
mechanics - Micromechanics of the lung (dogs, rats)
POlHL-14985-07 0004 Adaptation to hypoxia - Control of
breathing in respiratory failure (human, dogs)
POlHL-14985-07 0009 Adaptation to hypoxia - Influence
of chemosensitivity on control of breathing during sleep
(human, dogs)
ROlHL-15526-05 Respiratory mechanics in children
ROlHL-16463-05 Localization of airways obstruction and
responses
POlHL-16878-05 0001 Control of ventilation in health
and disease - Ability of asthmatics to detect added
resistive and elastic loads
POlHL-17731-04 0006 Physiological basis of pulmonary
disease - Ventilation-perfusion ratios (human, dogs)
ROlHL-17776-04 Pulmonary mucus transport in
obstructive lung diseases (human)
ROlHL-17873-04 Pathophysiology of exercise-induced
asthma (human)
ROlHL-18070-04 Regulation of intrapulmonary airways
and vessels (human, animals)
ROlHL-19062-03 Pharmacologic control of mast cell
phosphodiesterase (human, rats)
R01HL19722-03 Aerosol growth In the respiratory system
(models)
ROlHL-20024-03 Therapeutic aerosols-Characteristics and
retention (human, dogs)
ROlHL-20184-02 Desensitization of tracheal muscle to
isoproterenol (rats, rabbits)
ROlHL-20783-02 Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
R23HL-20968-02 Respiratory failure-Control and muscle
dysfunction (human)
ROlHL-20989-01 Pathophysiology of bronchial asthma
(sheep, dogs)
ROlHL-21444-02 Pulmonary mechanics during postnatal
development (human)
ROlHL-22065-01 Intractability, medication, and coping
styles in asthma (human)
R23HL-22920-01 Dynamic airway behavior (dogs)
ROlHL-2358606 Pharmacologic control of hypersensitivity
phenomena (human)
RESPIRATORY DRUGS, EXPECTORANTS AND
MUCOLYTICS
ROlHL-13824-06 Defense mechanisms In pathogenesis of
emphysema (human, dogs)
R01HL-148A4-06 Mucous glycoprotein In human respiratory
epithelium (also wheat)
ROlHL-16730-03 Physiology of mucociliary transport (rati.
frogs, rabbits)
(eenM)
•IS
ROIHI'17776 04 Pulmonary mucus transport in
obstructiv* lung distasas (human)
ROIHI 1830803 Compiahansivt studits ot mucociliary
transport (dogs)
lESPIRATORY ENZYMES
SE£ RtSPIRMORY PROTEINS. RESPIRATORY EN/YMES
RESPIRATORY EXAMINATIONS
SEE RESPIRATORY OISOROERS DIAGNOSIS'
RESPIRATORY FAILURE (GENERAL)
SEE RESPIRATORY DISORDERS. RESPIRATORY INSUFFICIENCY
(GENERAL)
RESPIRATORY FUNCTION
ROIHL 04651 19 Remote stimulation by radiolrequency
transmission (dogs, human)
M POIHL'04664 18 Cardiovascular and lung dynamics
POIHL'04664 18 OOOS Cardiovascular and lung dynamics
Applications ot current research, equipment and
techniques
POIHL 04664 18 0010 Cardiovascular and lung dynamics
' Lett ventricular dynamics (human)
M POIHL'06285 18 Cardiovascular-respiratory physiology and
biochemistry
*• POlHL-0628518 0180 Cardiovascular-respiratory
physiology and biochemistry Vagal C-fibers and their
influence on visceral and somatic function (animals)
M POlHL-06296'18 Cardiovascular and pulmonary
adaptation to stress
POlHL-06664-17 0043 Cardiopulmonary function in
remediable vascular disease - Alveolar hypoxic
vasoconstriction-Control and clinical significance (dog.
human)
** POlHL-07896-15 0021 Environmental biomedical research
program - Liquid breathing and lung lavage (human)
POlHL-07896-15 0029 Environmental biomedical research
program - Oxygen-helium diving resulting in high pressure
nervous syndrome (human, animals)
M POlHL-08805-15 Regulation of ventilation and pulmonary
circulation
Regulation of ventilation and
Electron microscope core research
P01HL08805-15 0042
pulmonary circulation
laboratory
P01HL0880515 0044
pulmonary circulation
Regulation of ventilation and
Neurochemical Interactions in
respiratory control (human, dogs, goats)
POlHL-08805-15 0045 Regulation of ventilation and
pulmonary circulation - Integrated description of
neurochemical respiratory control system
POlHL-08899-14 0006 Tolerance to respiratory gases in
health and disease - Effects of extreme pressures of inert
gases in macaque monkey
POlHL-0889914 0018 Tolerance to respiratory gases in
health and disease - Effects of respiratory gases at
extreme pressures (human)
POlHL-08899-14 0036 Tolerance to respiratory gases in
health and disease - Chemical and neurogenic components
of respiratory simulation in exercise (human)
P01HL08899-14 0044 Tolerance to respiratory gases in
health and disease - Influence of high oxygen pressures on
cognition and performance
POlHL-08899-14 0064 Tolerance to respiratory gases in
health and disease - Narcotic effects of inert gases on
functional systems (rats)
P01HL10342-13 0026 The integrated function of
respiration and circulation - Control of respiration-
Characterization of the aortic body (cats)
POlHL-10342-13 0028 The integrated function of
respiration and circulation - Mediator release,
hemodynamics and respiratory function in anaphylaxis
(dogs)
POlHL-11678-11 0017 Cardiovascular dynamics and their
control - Overall control of circulation-Mathematical
analyses
ROlHL-13172-10 Post-trauma lung mechanics and fluid
exchange (human, dogs, monkeys)
ROlHL-13315-08 Disposition of vasoactive hormones in
mammalian lung (rats, rabbits, human)
POlHL-13738-08 0002 Cardiac assist devices and
artificial hearts - Total replacement with artificial heart
(calves, sheep, ponies)
ROlHL-13824-06 Defense mechanisms in pathogenesis of
emphysema (human, dogs)
ROlHL-14102-07 Human physiology at 5360 meters-
Mountain environment
P50HL-14136-07 0003 Pulmonary SCOR-Airways
obstructive diseases - Acute pediatric respiratory disease
and COLD
■ P50HL1413607 0017
obstructive diseases
(human)
' P50HL-14136-07 9002
obstructive diseases
' P50HL-1413607 9006
obstructive diseases
P50HL141S3-07 0012
Pulmonary SCOR-Airways
Pediatric airways obstructive disease
Pulmonary SCOR-Airways
Physiology core (human, animal)
Pulmonary SCOR-Airways
Pediatric lung function core
Johns Hopkins Lung Center-
Chronic diseases of airways - Aspirin Intolerance In
revartlblt lung dlsaase (human)
P50HL-U153-07 0018 Johns Hopkins Lung Center-
Chronic disaaies of airways ■ Pulmonary function core
471
P50HL 1 4 1 8 7 0 / 0005 Pulmonary SCOR Chemical
mediators in pulmonary vascular responses Pulmonary
hypertension and cardiac function (dogs, human)
P50HL 14214 0/ 0012 Newborn lung center for hyaline
membrane disease Pulmonary status of children who had
HMD as infants
P50HL 14218 07 0014 Pulmonary SCOR Newborn lung
center Longitudinal study ot RDS Monitoring fetal
breathing movements (human)
P50HI 1421807 0015 Pulmonary SCOR Newborn lung
center Long term follow up of infants surviving RDS
Neurological outcome (human)
POIHL 1441407 Environmental influences on
cardiorespiratory and cellular functions
POIHL 14414 07 0003 Environmental influences on
cardiorespiratory and cellular functions Exposure to
abnormal gaseous environments (human, dogs, rabbits)
POIHL 14414 07 0008 Environmental influences on
cardiorespiratory and cellular functions Energetics of
swimming (human)
POIHL 14414-07 0015 Environmental influences on
cardiorespiratory and cellular functions Control of the
cardiovascular system (dogs)
ROIHL 14495-05 Solid and structural mechanics of lungs
(mammals)
POlHL-14580 07 Program project in respiratory mechanics
POlHL-14580-07 0001 Program project in respiratory
mechanics Micromechanics of the lung (dogs, rats)
' POlHL-14580-07 0002 Program project in respiratory
mechanics Airway aerodynamics (human, dogs)
' POlHL-14580-07 0005 Program project in respiratory
mechanics Development and evaluation ol tests of
pulmonary function (human)
' R01HL-1SO13-07 Lung oxidative metabolism and energy
production (rodents, rabbits)
' P50HL-15061-07 0013 Response of lung to injury
Exchange transfusion in infants with respiratory distress
syndrome (human, sheep)
P50HL-15092-07 0002 Immune and fibrotic response to
occupational environments - Longitudinal study of
sandblasters silicosis (human)
P50HL-15092-07 0005 Immune and fibrotic response to
occupational environments Respiratory and Immunologic
evaluation of toluene diisocyanate exposure (human)
P50HL- 15092-07 0011 Immune and fibrotic response to
occupational environments - Respiratoiy and immunologic
responses in coffee plant workers
P60HL-15169-05 0015 Support for center for sickle cell
disease - Pathophysiology of acute pulmonary infiltrates in
sickle cell disease (human)
P50HL-15389-07 0008 Pulmonary SCOR-Hypersensitivity
pneumonitis • Milwaukee patient study-Hypersensitivity
pneumonitis
* P50HL- 153 89-07 0016 Pulmonary SCOR-Hypersensitivity
pneumonitis - Pulmonary physiology core (human)
ROlHL-15430-05 Cardiopulmonary adaptation of newborns
to altitude (human)
ROlHL-15614-04 Heredity and oxygen-Effects on health of
heart-lungs (South America)
POIHL 15832-06 Chemical-structural predispositions to
lung injury
POlHL-15832-06 0002 Chemical-structural predispositions
to lung injury - Connective tissue in lung in development
and repair of injury (human, rats, mice)
* POlHL-15832-06 9001 Chemical-structural predispositions
to lung Injury - Tissue culture studies of lung cell function-
Core facility
1 POlHL-16137-05 Alveolar biology
* ROIHL- 164 30-05 Neural control of respiration (cats)
R01HL-16651-0S Evaluation of steroid therapy in
sarcoidosis (human)
ROlHL-16730-03 Physiology of mucociliary transport (rats,
frogs, rabbits)
* ROlHL-17246-03 Oxygen uptake at one minute of exercise
(human)
* P60HL-17292-04 0008 Vermont Lung Center - Respiratory
physiology-Teaching, learning and auditing problem -solving
skills
P60HL-17292-04 0029 Vermont Lung Center - Computer-
assisted pre-operative evaluation (human)
ROlHL-17352-03 Physiological regulation during chronic
hyperthermia (sheep)
* P01HL-17382-0S 0001 Chemical mediators of acute
pulmonary disorders - Chemical mediators and respiratoiy
mechanics in humans
* POlHL-17382-05 0002 Chemical mediators of acute
pulmonary disorders - Chemical mediators and respiratory
mechanics in guinea pigs
ROlHL-17437-03 'Perfusion lung'-Role of traumatized
leukocytes (dogs, human)
ROlHL-17543-03 0004 Magnetic tracers for diagnosis of
lung disease - Magnetite retention, distribution, relaxation
rate, viscosity (rabbits)
* ROlHL-17689-06 Neurophysiologic studies of respiratory
control (cats)
ROIHL'177 15-04 Respiratory muscle afferents in
respiratory control (cats)
* ROlHL-177 19-03 Lung Injury, substrate utilization, oxygen
toxicity (rats, rabbits, dogs)
POlHL-17731-04 0002 Physiological basis of pulmonary
disease - Biomechanics of the lung (frogs, cats)
RES
POIHI 17731 04 0003 Phytiological batii of pulmonary
disease Comparative phytiology Ivertebratei)
POIHL 1/731 04 000/ Phytiological bans ol pulmonary
disease Theoretical gas exchange
ROIHI 1/944 03 Studies in lung preservation (dogtl
ROIHL 18143 03 Surgery and pulmonary tusue alteralioni
(dogs. rats, human)
P50HL 1917002 Harvard pulmonary SCOR Chronic
diseases ol the airways
P50HL 191/0 02 000/ Harvard pulmonary SCOR Chronic
diseases of the airways Therapy effect on airway
obstruction in acute asthma (human)
P50HL 191/002 0009 Harvard pulmonary SCOR Chronic
diseases of the airways Ventilatory muscle training in
chronic obstructive pulmonary disease (human)
P50HL 19171 02 0001 Pulmonary SCOR Lung in|ury by
childhood infections Longitudinal study Respiratory
infections and lung growth in normal children
P50HL 19171 02 0004 Pulmonary SCOR Lung injury by
childhood infections Long term effects of respiratory
infections in early childhood
P50HL 19171 02 0011 Pulmonary SCOR Lung injury by
childhood infections Clinical support core
P50HL-19185-02 0011 Pulmonary SCOR Neonatal
respiratory distress syndromes Complications and
sequelae of neonatal respiratory distress (human)
P50HL 19190-02 Pulmonary SCOR -Pathophysiology,
management of IRDS
' R01HL19195-03 Hormonal regulation of lung function
(rats)
ROIHL 19225-02 Types and mechanims of pulmonary
hypertension
■ ROIHL 1922502 0003 Types and mechanims of
pulmonary hypertension Cardiopulmonary function in pigs
and rats
P50HL19362-02 0006 A/S SCOR -Atherosclerosis in
nonhuman primates - Effects of cigarette smoking on
atherosclerosis (baboon)
P50HL-19362-02 0007 A/S SCOR-Alherosclerosis in
nonhuman primates Behavior type, cigarette smoking and
atherosclerosis (baboon)
ROlHL-19379-03 Characterization of small-granule cells in
the lung (mammals)
R23HL19573-01 Studies on pulmonary serotonin (mice)
POIHL 19717-02 0006 Response of the lung to injury -
Glycosaminoglycans and proteoglycans of the lung (human,
rats, hamsters)
' POlHL-1971702 0010 Response of the lung to injury -
Proteoglycans in lung function and structure (hamsters)
POlHL-19717-02 0011 Response of the lung to injury -
Physiological characterization of the elastase model
(hamsters)
' POlHL-19717-02 0037 Response of the lung to injury -
Catecholamines, prostaglandins and nucleotides in
pulmonary function (animals)
POlHL-19737-02 Cellular and molecular aspects of
respiratory physiology
Cellular and molecular aspects of
Fatty acid metabolism in type II
POlHL-19737-02 0001
respiratory physiology
alveolar cells (rats)
POlHL-19737-02 0011
respiratory physiology
Cellular and molecular aspects of
Chemical and metabolic factors on
peripheral chemoreceptor activity (cats)
ROlHL-20105-02 Deposition of hygroscopic aerosols in
bronchi (dogs, human, models)
ROlHL-20192-02 Ciliary activity of the lung studied by
laser scattering
ROlHL-20347-02 Bolus-response measurement of lung
function (human)
ROlHL-20548-02 Innervation of the lung (rats, monkeys)
ROlHL-20773-02 Surfactant, pulmonary edema, and lung
mechanics (rabbits)
ROlHL-20783-02 Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
ROlHL-20800-17 Neural basis of respiratory and
vasomotor activity (cats)
ROlHL-20875-02 Chronic obstructive pulmonary disease-
Familial/genetic (human)
ROlHL-21 126-02 Exercise-induced bronchospasm in
children
R23HL-2116801 Hypoxemic respiratory failure-Physiologic
evaluation (human, dogs)
R01HL-213S2-02 Community studies of obstructive lung
disease (human)
ROlHL-21565-02 Pathogenesis of inflammatory lung Injury
(rats, rabbits)
POlHL-2 1584-02 9001 Respiratory mechanics in normal
and abnormal states - Technical and equipment core
POlHL-2 1584-02 9002 Respiratory mechanics in normal
and abnormal states - Computational and statistical core
facility
R23HL-21954-01 Exercise conditioning in patients with
cystic fibrosis
R13HL-22159-01 Conference en non-ventilatory functions
of the lungs (New Hampshire)
ROlHL-22178-01 Lung airway properties by acoustic
impulse reflection
ROlHL-22333-01 Cellular basis of small airways function
(rats)
R23HL-22346-01 Hematological injury and pulmonary
dysfunction (human, mammals)
(contd)
'EncludM routine mtthodotogy OR coven only general projtcti which prtcludt Indexing at the ipecltic Itvel.
"Oflanttd significantly to abov* lubject.
M Grant has subpnijects dascrlbing specific research aspects.
See Appandls for investigator's name and grant number.
RES
472
RES
** ROlHL-22418-01 Neural control of cardiorespiratory
functiot^ (cats)
ROlHL-22517-01 Engineering development of an ultrasonic
ventilometer (human)
ROlHL-22520-01 Pulmonary vascular response to group B
Streptococci (human, mammals)
** ROlHL-22528-02 Early risk predictors for chronic
pulmonary disease (human)
** ROlHL-2263601 Newborn lung function during
mechanical ventilation (human)
ROlHL-22661-01 Chronic total cardiopulhonary mechanical
substitution (sheep)
ROIHL'22715'01 Neural Integration of the cardiovascular
reflexes (dogs))
** ROlHL-22844-01 Phrenic nerve pacing-Noninvasive
diaphragm analysis (human, dogs)
** ROlHL-2360101 Early hypoxia and development of
respiratory control
** ROlHL-23981-01 Acute alveolar injury (dogs)
NOlHR-3290207 Pilot study to standardize the
measurement of closing volume (human)
NOlHR-72972-01 Self-management for asthmatic children
NOlHR-72974-01 Self-management systems for asthmatic
children
RESPIRATORY FUNCTION, APNEA
POlHL-06285-18 0181 Cardiovascular-respiratory
physiology and biochemistry - Regulation of respiration-
Role of vagus nerve (dogs)
P50HL-14214-07 0027 Newborn lung center for hyaline
membrane disease - Oral-laryngeal chemoreceptors and
respiratory failure in newborns (human, sheep)
P50HL-14214-07 0029 Newborn lung center for hyaline
membrane disease ■ The diving reflex -Perinatal asphyxia,
pulmonary ischemia and HMD (sheep)
R01HL-14e93-07 Survival value of physiological responses
to hypoxia (dogs)
ROlHL-15659-05 Dynamic isolation studies of control of
respiration (human)
ROlHL-18007-05 Neural mechanisms controling motor act
of breathing (cats, human)
P50HL-19187-02 0009 Pediatric pulmonary SCOR-Hyaline
membrane disease ■ Non-invasive measurement and
monitoring of arterial oxygen tension (dogs, sheep)
P50HL-19187-02 0010 Pediatric pulmonary SCOR-Hyaline
membrane disease - Treatment, outcome of HMD-
Continuous positive airway pressure (human, monkey)
P50HL-19187-02 0012 Pediatric pulmonary SCOR-Hyaline
membrane disease - Resource requirements, economic
consequence of HMD and recurrent apnea
ROlHL-22418-01 Neural control of cardio-respiratory
function (cats)
ROlHL-23601-01 Early hypoxia and development of
respiratory control
RESPIRATORY FUNCTION, BRONCHOMOTION
** POlHL-06664-17 0043 Cardiopulmonary function in
remediable vascular disease - Alveolar hypoxic
vasoconstriction-Control and clinical significance (dog,
human)
P50HL-14153-07 0017 Johns Hopkins Lung Center-
Chronic diseases of airways - Collateral ventilation and
pulmonary interdependence (pig, dog, human)
POlHL-14580-07 0001 Program project in respiratory
mechanics ■ Micromechanics of the lung (dogs, rats)
R01HL18070-04 Regulation of intrapulmonary airways
and vessels (human, animals)
ROlHL-191 15-02 Hormonal control of tracheobronchial
cyclic AMP (rats, guinea pigs)
P50HL-19156-02 0001 Pulmonary SCOR-Chronic diseases
of airways - Irritability of airways induced by epithelial
damage in healthy subjects (human)
P50HL-19156-02 0004 Pulmonary SCOR-Chronic diseases
of airways - Interactions between mast cells, mediators
and nerves in canine asthma
** P50HL-19156-02 0005 Pulmonary SCOR-Chronic diseases
of airways - Vagal receptors in the airway-Epithelial injury
and antigen (dog, cat, rabbit)
ROlHL-20122-02 Operational mechanisms of airway
receptors (dogs, pigs)
ROlHL-22415-01 Mechanisms responsible for disease
severity in asthma (human)
" R23HL-22920-01 Dynamic airway behavior (dogs)
RESPIRATORY FUNCTION, HYPERPNEA
POlHL-06285-18 0181 Cardiovascular-respiratory
physiology and biochemistry - Regulation of respiration-
Role of vagus nerve (dogs)
POlHL-1 1678-11 0009 Cardiovascular dynamics and their
control - Control of respiration (cat, human)
** ROlHL-1 1907-08 Mechanisms of physiological responses
to exercise (human, dogs)
ROlHL-14693-07 Survival value of physiological responses
to hypoxia (dogs)
ROlHL-14717-06 Hemodynamics and heart structure-
Ventricular overload (dogs)
ROlHL-14967-06 Chemoreceptor function in dynamic
ventilatory control (human, dogs)
POlHL-14985-07 0008 Adaptation to hypoxia - Ventilatory
drive and exercise capacity (human, dogs)
ROlHL-15659-05 Dynamic isolation studies of control of
respiration (human)
ROlHL-16022-05 Determinants of the ventilatory response
to hypoxia (goats, cats)
POlHL-161 18-06 0005 Study of emphysema -
Mechanisms of elastase emphysema (mice)
ROlHL-16390-05
exercise (dogs)
ROlHL-17873-04
Cardiopulmonary control coupling in
Pathophysiology of exercise-induced
asthma (human)
R01HL18371-03 Pulmonary hypertension and ventilation
pathophysiology (dogs)
" ROlHL-19410-03 Dynamic interrelations underlying
exercise hyperpnea (human)
ROlHL-19827-02 Role of the upper airways in the control
of breathing (human, cats, dogs)
ROlHL-21318-02 Mechanisms of emotions' asthma
triggering effect (human)
R23HL-21990-01 Accuracy of the ventilatory response to
exercise (dogs)
RESPIRATORY FUNCTION, HYPOVENTILATION
(GENERAL)
POlHL-08805-15 0044 Regulation of ventilation and
pulmonary circulation - Neurochemical interactions in
respiratory control (human, dogs, goats)
POlHL-14985-07 0004 Adaptation to hypoxia - Control of
breathing in respiratory failure (human, dogs)
POlHL-14985-07 0009 Adaptation to hypoxia - Influence
of chemosensitivity on control of breathing during sleep
(human, dogs)
POIHL 14985-07 0013 Adaptation to hypoxia - Chronic
mountain sickness (men)
R01HL-22622-0I Sleep apnea and desaturation-
mechanisms and incidence (human)
RESPIRATORY FUNCTION, HYPOVENTILATION,
RESPIRATORY CENTER DYSFUNCTION
ROlHL-14102-07 Human physiology at 5360 meters-
Mountain environment
** POlHL-14985-07 0009 Adaptation to hypoxia - Influence
of chemosensitivity on control of breathing during sleep
(human, dogs)
** ROlHL-16325-03 Breathing patterns in man
P50HL-19187-02 0011 Pediatric pulmonary SCOR-Hyaline
membrane disease - Effects of hypoxia and hypercapnia on
developing nervous system (monkey, human)
** R23HL-20968-02 Respiratory failure-Control and muscle
dysfunction (human)
ROIHL-21257-02 Breathing in sleep -Airway control and
blood gases (cats)
** ROlHL-22622-01 Sleep apnea and desaturation-
mechanisms and incidence (human)
RESPIRATORY FUNCTION, LIQUIDS BREATHING
SEE ALSO RESPIRATORY ASSIST AND OXYGEN
ADMINISTRATION. FLUOROCARBON
M POlHL-07896-15 Environmental biomedical research
program
** POlHL-07896-15 0021 Environmental biomedical research
program ■ Liquid breathing and lung lavage (human)
POlHL-07896-15 0029 Environmental biomedical research
program - Oxygen-helium diving resulting in high pressure
nervous syndrome (human, animals)
** ROlHL-22843-01 Pulmonary physiology in liquid ventilation
(lambs)
RESPIRATORY FUNCTION, PULMONARY
DIFFUSION
SEE ALSO RESPIRATORY CIRCULATION. PULMONARY
CIRCULATION
** POIHL-06296-18 0002 Cardiovascular and pulmonary
adaptation to stress - Respiratory muscle blood flow,
mechanics and metabolism (human, dog)
** POlHL-10342-13 0014 The integrated function of
respiration and circulation - Oxygen and carbon monxide
transfer (human, dogs, sheep)
** POlHL-10342-13 0023 The integrated function of
respiration and circulation - Carbon dioxide transport and
CSF acid base balance (hogs, pigs)
** POlHL-10342-13 0025 The integrated function of
respiration and circulation - Pulmonary gas exchange and
metabolism (human, dogs, sheep)
ROlHL-10622-12 Volumes and compliance of pulmonary
circulation (human, dogs)
** ROlHL-121 74-11 Ventilation/perfusion distribution in the
lung (human, mammals)
P50HL-141 53-07 0018 Johns Hopkins Lung Center-
Chronic diseases of airways - Pulmonary function core
** P50HL-14187-07 0015 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses -
Pathophysiologic responses of pulmonary capillary bed
(dog. human)
M POlHL-144 14-07 Environmental influences on
cardiorespiratory and cellular functions
** POlHL-144 14-07 0003 Environmental influences on
cardiorespiratory and cellular functions - Exposure to
abnormal gaseous environments (human, dogs, rabbits)
" POlHL-14985-07 0002 Adaptation to hypoxia - Oxygen
transport in man at high altitude
P50HL-15061-07 0004 Response of lung to injury -
Biochemical abnormalities in connective tissues (rats)
P60HL-1 51 60-07 0015 Center for sickle cell disease -
Lung function abnormalities in sickle cell
hemoglobinopathies (human)
** POlHL-15194-07 0006 Pathophysiology of
cardiopulmonary dysfunction - Kinetics of gas exchange-
Velocity of Bohr effect in erythrocytes (human)
** POlHL-15194-07 0009 Pathophysiology of
cardiopulmonary dysfunction - Kinetics of gas exchange-
Diffusion and erythrocytes reaction rates (human, dogs)
** POlHL-15194-07 0022 Pathophysiology of
cardiopulmonary dysfunction - Kinetics of gas exchange -
Pulmonary carbon dioxide exchange (dogs)
♦* POlHL-15194-07 0023 Pathophysiology of
cardiopulmonary dysfunction - Distribution of ventilation-
Diffusion and cardiogenic agitation (dogs)
P50HL-15389-07 0016 Pulmonary SCOR-Hypersensitivity
pneumonitis • Pulmonary physiology core (human)
ROlHL-16154-05 Membrane lung perfusion for acute
respiratory failure (sheep, baboons)
ROlHL-16674-05 Airborne metals and lung permeability
(bullfrogs, rats)
M P01HL17731-04 Physiological basis of pulmonary disease
POlHL-17731-04 0001 Physiological basis of pulmonary
disease - Mechanisms of blood flow and ventilation (dogs)
POlHL-17731-04 0003 Physiological basis of pulmonary
disease - Comparative physiology (vertebrates)
** POlHL-17731-04 0006 Physiological basis of pulmonary
disease - Ventilation-perfusion ratios (human, dogs)
" POlHL-17731-04 0007 Physiological basis of pulmonary
disease - Theoretical gas exchange
POlHL-17731-04 0010 Physiological basis of pulmonary
disease - Gas exchange kinetics (dogs)
POlHL-17731-04 0011 Physiological basis of pulmonary
disease ■ Morphometric studies of the lung -Core
** POlHL-17813-04 0001 Lung disease and the oxygenation
of blood and tissue - Diffuse interstitial lung disease-
Pathophysiology (human, dogs)
** ROlHL-18022-03 Role of multicomponent diffusion in gas
exchange (avian eggs)
** R01HL18028-03 Absorption of nonvolatile compounds
from the lung
P50HL-19155-02 0002 Pathophysiology of pulmonary
edema Non invasive measurement of protein turnover In
human lung (also sheep)
P50HL-19155-02 0005 Pathophysiology of pulmonary
edema - Protein exchange sites and lymph protein
concentration in lung (mice, sheep)
P50HL19156-02 0002 Pulmonary SCOR-Chronic diseases
of airways - Early detection of emphysema and chronic
airway obstruction (human, dog)
P50HL-19187-02 0001 Pediatric pulmonary SCOR-Hyaline
membrane disease - Hyaline membrane disease-Changes
in lung mechanics and gas exchange (monkeys)
POlHL-19717-02 0008 Response of the lung to injury -
Experimental models of lung disease
** ROlHL-19733-03 Absorption of antigen through inflamed
lungs (rabbits)
** POlHL-19737-02 0010 Cellular and molecular aspects of
respiratory physiology - Effects of pulsatile flow and volume
on capillary exchanges (dogs, rats)
R23HL-20576-01 Airway turbulence and pulmonary oxygen
exchange
R23HL-21 168-01 Hypoxemic respiratory failure-Physiologic
evaluation (human, dogs)
ROlHL-21948-01 Capillary, tissue volume and lymph flow
in lung edema (sheep, cattle)
** R23HL-22932-01 Effect of carbon dioxide on local gas
exchange (dogs)
** ROlHL-22976-01 Nonuniform ventilation and diffusing
capacity (human)
RESPIRATORY FUNCTION, PULMONARY
VENTILATION
R01HL02888-22 Interrelationships of circulation and
respiration (opossum, cats)
POlHL-04664-18 0002 Cardiovascular and lung dynamics
- X-ray cross section imaging of organs (dogs)
POlHL-06285-18 0180 Cardiovascular-respiratory
physiology and biochemistry - Vagal C-fibers and their
influence on visceral and somatic function (animals)
POlHL-06285-18 0181 Cardiovascular-respiratory
physiology and biochemistry - Regulation of respiration-
Role of vagus nerve (dogs)
POlHL-06285-18 0208 Cardiovascular-respiratory
physiology and biochemistry - Composition, properties and
turnover of pulmonary surfactant (human, animals)
POlHL-06296-18 0002 Cardiovascular and pulmonary
adaptation to stress ■ Respiratory muscle blood flow,
mechanics and metabolism (human, dog)
POlHL-07896-15 0014 Environmental biomedical research
program - Mechanisms of respiration and circulation
(human, dogs)
POlHL-07896-15 0036 Environmental biomedical research
program - Respiratory heat loss in deep diving (infants.
dogs)
** POlHL-07896-15 0048 Environmental biomedical research
program • Respiratory performance in divers at 1400 FSW
POlHL-07896-15 0058 Environmental biomedical research
program - Lung synthesis of disaturated
phosphatidylcholine (rats. dogs, bats)
POlHL-07896-15 0063 Environmental biomedical research
program - Oxygen toxicity (baboons)
** ROlHL-08789-11 Respiratory muscles and ventilatory
control in man (and dogs)
** POlHL-08805-15 0006 Regulation of ventilation and
pulmonary circulation - Adaptation of lungfish-Estivation
(contd)
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
RES
P01Hl0880i IS 002b
pulmonary circulation
POIHL0B80S IS 0044
pulmonaiY circulation
Regulation ol ventilation and
Pulmonary edema (rabbits)
Reilulatron ol ventilation and
Neurochemical inteiactions in
respiratory control (human, dogs, goals)
POIHI 08805 15 0046 Regulation ol ventilation and
pulmonary circulation Sites and modes of interaction ot
peripheral and central chemoreceptors
POIHL 08805 15 004/ Regulation ol ventilation and
pulmonary circulation Extracranial metabolic control ot
ventilation (dogs, goats)
POIHL 08899 14 OOU Tolerance to respiratory gases in
health and disease Pulmonary tolerance (human, dogs)
Tolerance to respiratory gases in
Oxygen tolerance (human, rats.
POIHL 08899 14 0020
health and disease
guinea pigs)
POIHL 08899 14 0025
health and disease
Cardiorespiratory control in exercise
Tolerance to respiratory gases in
Effects ol oxygen on cardiopulmonary
gas transport functions (dogs)
R01HL10009 13 Regional lung function in man
POIHL 10342 13 0006 The integrated function of
respiration and circulation Lung inflation effects on
pulmonary vasculature and interstitial space (dogs)
POlHL-1034213 0008 The integrated function of
respiration and circulation Respiratory mechanics and the
circulation (human, dogs)
P01HL1034213 0014 The integrated function of
respiration and circulation Oxygen and carbon monxide
transfer (human, dogs, sheep)
P01HL10342 13 0023 The integrated function of
respiration and circulation - Carbon dioxide transport and
CSF acid base balance (hogs, pigs)
P01HL10342 13 0025 The integrated function of
respiration and circulation - Pulmonary gas exchange and
metabolism (human, dogs, sheep)
POlHL-10436 13 0001 A multidisciplmary study of
congenital heart disease - Assessment of the outlook for
children with congenital heart disease
P01HL10436-13 0005 A multidisciplmary study of
congenital heart disease - Pulmonary physiology in
congenital heart disease (human)
R01HL1062212 Volumes and compliance of pulmonary
circulation (human, dogs)
POIHLI 1678-11 0009 Cardiovascular dynamics and their
control • Control of respiration (cat. human)
ROIHLI 1907-08 Mechanisms of physiological responses
to exercise (human, dogs)
ROlHL-1217411 Ventilation/perfusion distribution in the
lung (human, mammals)
R01HL12530-10 Emphysema -Respiratory function in
disease (human, dogs, rats)
ROlHL-12564-09 Control of respiration and blood gases
(human, dog)
ROlHL-1323308
(human)
ROlHL-13824-06 Defense mechanisms in pathogenesis of
emphysema (human, dogs)
ROlHL-13841-16 Respiration during altitude
acclimatization (goats, dogs, rats, rabbits)
ROlHL-13885-08 9001 Cystic fibrosis and pulmonary
disease - Pulmonary function core facility (infants,
children)
ROlHL-13888-15 Regulation of respiration
ROlHL-1392107 The lung as a metabolic organ (animals)
R01HL1410207 Human physiology at 5360 meters-
Mountain environment
P50HL14136-07 0001 Pulmonary SCOR -Airviays
obstructive diseases - Experimental airway obstructive
disease (dogs)
P50HL-14136-07 0017
obstructive diseases
(human)
P50HL-14153-07 0017 Johns Hopkins Lung Center-
Chronic diseases of airways - Collateral ventilation and
pulmonary interdependence (pig, dog, human)
P50HL14214-07 0030 Newborn lung center for hyaline
membrane disease - Effects of ductal patency-Impedance
cardiography and echocardiography (human)
P01HL14414-07 0007 Environmental influences on
cardiorespiratory and cellular functions - Neural control of
respiration (human, cats)
POlHL-144 14-07 0008 Environmental influences on
cardiorespiratory and cellular functions - Energetics of
swimming (human)
POlHL-14580-07 0001 Program project in respiratory
mechanics - Micromechanics of the lung (dogs, rats)
' POlHL-14580-07 0003 Program project in respiratory
mechanics • Chest wall mechanics and respiratory control
(human, dogs)
ROlHL-14693-07 Survival value of physiological responses
to hypoxia (dogs)
ROlHL-14854-07 Lung and tissue mechanics (monkeys,
dogs)
' ROlHL-14870-06 Dynamics of oxygen and carbon dioxide
regulation (animals)
' ROlHL-14967-06 Chemoreceptor function in dynamic
ventilatory control (human, dogs)
P01HL-14985-07 Adaptation to hypoxia
POlHL-14985-07 0002 Adaptation to hypoxia - Oxygen
transport in man at high altitude
' POlHL-14985-07 0004 Adaptation to hypoxia - Control of
breathing in respiratory failure (human, dogs)
Pulmonary SCOR-Airways
Pediatric airways obstructive disease
473
POIHL 14985 0/ 0005 Adaptation to hypoiia Control
mechanisms in the pulmonary microciiculation (animals)
* POIHI 14985 07 0008 Adaptation to liypoxia Vcnlilatom
drive and exercise capacity (human, dogs)
POIHI 149850/ 0009 Adaptation lo hypoma Influence
ol chomosensitivity on control of breathing during sleep
(human, dogs)
POIHL 14985 07 0010 Adaptation to hypoxia Pulmonary
mast cell (animals)
POIHL 14985 07 0011 Adaptation to hypoxia
Prostaglandins in the control of the pulmonary circulation
(animals)
POIHL 1498507 0015 Adaptation to hypoxia Pregnancy
at high altitude (human, animals)
P50HL 15061 0/ 0013 Response of lung to injury
Exchange transfusion in infants with respiratory distress
syndrome (human, sheep)
P60HL 1516007 0015 Center lor sickle cell disease ■
Lung function abnormalities in sickle cell
hemoglobinopathies (human)
M POlHL-15194 07 Pathophysiology ol cardiopulmonary
dysfunction
•* POlHL-15194 07 OOU Pathophysiology of
cardiopulmonary dysfunction Distribution of ventilation -
Oxygen effects on intrapulmonary shunting (human)
** POIHL-15194-07 0023 Pathophysiology of
cardiopulmonary dysfunction Distribution ol ventilation -
Diffusion and cardiogenic agitation (dogs)
** POIHL 15194-07 0024 Pathophysiology of
cardiopulmonary dysfunction Distribution of ventilation-
Airflow limitation in COLD (human)
P50HL- 15389-07 0016 Pulmonary SCOR- Hypersensitivity
pneumonitis Pulmonary physiology core (human)
ROlHL-15430-05 Cardiopulmonary adaptation of newborns
to altitude (human)
ROlHL-15469-06 Human ventilatory adaptation (also.
dogs, rats)
ROlHL-15659 05 Dynamic isolation studies of control of
respiration (human)
ROlHL-15694-06 Pulmonary factors in circulatory
regulation
** R01HL-16022-05 Determinants of the ventilatory response
to hypoxia (goats, cats)
ROlHL-16066-05 Studies on neurogenic control of the
circulation (human, dogs)
ROlHL-16325-03 Breathing patterns in man
** R01HL-16390-05 Cardiopulmonary control coupling in
exercise (dogs)
** ROlHL-15463-05 Localization of airways obstruction and
responses
POlHL-1683304 0016 Hemoglobin and red cell system in
hemoglobinopathies - Calcium-indiced membrane damage
in Hb SS disease (human, animals)
M POlHL-16878-05 Control of ventilation in health and
disease
** POlHL-16878-05 0001 Control of ventilation in health
and disease - Ability of asthmatics to detect added
resistive and elastic loads
** POlHL-16878-05 0003 Control of ventilation in health
and disease - Brain stem respiratory neurons in response
mechanical/chemical loading (animal)
** POlHL-16878-05 0004 Control of ventilation in health
and disease - Neurotransmitters in the respiratory system
(cats)
ROlHL-169 16-04 0001 The role of albumins in lung water
accumulation - Capillary permeability (dogs, human)
** ROlHL-17314-04 Effects of anesthesia and loading on
respiration (human, cats)
** ROlHL-17358-04 Ventilatory adjustments for optimal
oxygenation (dogs, rats)
ROlHL-17403-03 Metabolic control of cardiac output
(dogs)
P01HL17417-05 0005 Experimental lung transplantation
■ Lung transplantation in bilateral emphysema (dogs)
ROlHL-17578-04 Exercise performance in children with
heart disease
** P50HL-17682-04 0007 Study of ischemic heart disease -
Mechanisms of hypoxemia in myocardial infarction (human)
R01HL17689-06 Neurophysiologic studies of respiratory
control (cats)
M POlHL-17731-04 Physiological basis ot pulmonary disease
** P01HL17731-04 0001 Physiological basis of pulmonary
disease - Mechanisms of blood flow and ventilation (dogs)
POlHL-17731-04 0003 Physiological basis of pulmonary
disease - Comparative physiology (vertebrates)
** POlHL-17731-04 0006 Physiological basis of pulmonary
disease - Ventilation-perfusion ratios (human, dogs)
** POlHL-17731-04 0007 Physiological basis of pulmonary
disease ■ Theoretical gas exchange
POlHL-17731-04 OOU Physiological basis of pulmonary
disease - Morphometric studies of the lung-Core
** POlHL-17731-04 0012 Physiological basis of pulmonary
disease - Statistics and computing-Core
** ROlHL-17768-04 Development of collateral ventilation
(dogs, fish, horses)
M POlHL-178 13-04 Lung disease and the oxygenation of
blood and tissue
** POlHL-17813-04 0001 Lung disease and the oxygenation
of blood and tissue - Diffuse interstitial lung disease-
Pathophysiology (human, dogs)
POIHL 1/813 04 0006 Lung diMtte and Ihe oxygenation
ol blood and tiMue Atttitment ol reipiralory mu\i.l«
contractile force (human, dogil
ROIMI 18191 04 Models ol hypoxic pulmonary
hypertension (cattle, minipigs)
ROIHI 183/1 03 Pulmonary hypertension and ventilation
pathophysiology (dogs)
ROlHt 19056 03 Blood triglycerides and lipoprotein lipaie
in the lung (rats)
P50HL 19155 02 0001 Pathophysiology of pulmonary
edema Pulmonary edema study unit (human, dog)
P50HL 1915602 0002 Pulmonary SCOR Chronic diseases
of airways Early detection of emphysema and chronic
airway obstruction (human, dog)
P50HL 191/002 0003 Harvard pulmonary SCOR Chronic
diseases ol the airways Mechanisms of bronchial
reactivity to acute and chronic airway challenge (dog)
P50HL 191/0 02 0004 Harvard pulmonary SCOR Chronic
diseases ol the airways Exercise, increased ventilation
eftect on airway exposure and responses (rodent)
P50HL 1917002 0009 Harvard pulmonary SCOR Chronic
diseases of the airways Ventilatory muscle training in
chronic obstructive pulmonary disease (human)
P50HL 19185-02 0003 Pulmonary SCOR Neonatal
respiratory distress syndromes Factors affecting formation
and release of pulmonary surfactant in fetal lambs
P50HL 19185 02 0009 Pulmonary SCOR Neonatal
respiratory distress syndromes Nasal continuous positive
airway pressure in hyaline membrane disease (human)
' P50HL 19187-02 0001 Pediatric pulmonary SCOR -Hyaline
membrane disease Hyaline membrane disease-Changes
in lung mechanics and gas exchange (monkeys)
P50HL 19187 02 OOU Pediatric pulmonary SCOR -Hyaline
membrane disease Effects of hypoxia and hypercapnia on
developing nervous system (monkey, human)
' P50HL 19190-02 0006 Pulmonary SCOR Pathophysiology,
management of IRDS Asphyxia -Respiratory control (dogs)
P50HL 19190-02 0009 Pulmonary SCOR -Pathophysiology,
management of IRDS - Developing non-invasive neonatal
pulmonary monitoring systems (rabbit, human)
R01HL19225-02 0003 Types and mechanims of
pulmonary hypertension - Cardiopulmonary function in pigs
and rats
ROlHL-1924803 Breathing pattern variation and
mechanical influences
ROlHL-19410-03 Dynamic interrelations underlying
exercise hyperpnea (human)
ROlHL-1944903 Gas exchange in acute respiratory failure
POlHL-1971702 0046 Response of the lung to injury ■
Bioengineering section
* P01HL19737-02 0005 Cellular and molecular aspects of
respiratory physiology - Interaction of respiratory exchanges
and blood gas parameters (human, animals)
POlHL-19737-02 0010 Cellular and molecular aspects of
respiratory physiology Effects of pulsatile flow and volume
on capillary exchanges (dogs, rats)
ROlHL-20344-02 Regulation of protein turnover in lung
tissue (rats)
ROlHL-20347-02 Bolus-response measurement of lung
function (human)
ROlHL-20354-02 Direct determination of oxygen tension In
the clinical environment (human, dogs)
ROlHL-20366-03 Protein turnover and ammo acid
transport by lung (rats)
ROlHL-20548-02 Innervation of the lung (rats, monkeys)
ROlHL-20568-03 Respiration during prolonged hypercapnia
(rats)
ROlHL-20574-03
activity (cats)
R23HL-20576-01
exchange
ROlHL-20652-01
(dogs)
ROlHL-20719-02
(cattle)
■* ROlHL-20847-02
(human, goats)
■* R23HL-20968-02
dysfunction (human)
■* POlHL-20994-02 0008 Dynamics of neutrophil elastase in
the lung - Structure-function correlation in experimental
emphysema (human, dogs)
R01HL-2U17-01 Altitude adaptation in chronic lung
disease (human)
R23HL-21168-01 Hypoxemic respiratory failure-Physiologic
evaluation (human, dogs)
R23HL-21405-01 Respiratory muscles in regulation of
infant breathing (human)
R23HL-21409-02 Perinatal control of the ductus arteriosus
(sheep)
ROlHL-21500-02
stress (dogs)
" ROlHL-21518-01 Improvement in regional ventilation-
perfusion resolution (human)
R23HL-21539-02 Mechanical properties of isolated small
bronchioles (rabbits)
M POlHL-2 1584-02 Respiratory mechanics in normal and
abnormal states
** POlHL-21584-02 0001 Respiratory mechanics in normal
and abnormal states - Engineering analysis of lung
deformation (human, animals)
(contd)
Brain stem integration of chemoreceptor
Airway turbulence and pulmonary oxygen
Sites of leakage in pulmonary edema
Cold induced pulmonary hypertension
Respiratory neurochemical control
Respiratory failure -Control and muscle
Performance of respiratory muscles under
•Excludes routine methodology OR covers only general proiects which preclude indexing at the specific level.
**0nented significantly to above subject.
M Grant has suliprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
RES
474
RES
** POlHL-21584-02 0002 Respiratoof mechanics in normal
and abnormal states - Lung mechanics-Regional
deformation and ventilation (dogs)
*• POlHL-21584-02 0003 Respiratory mechanics in normal
and abnormal states - Effects of anesthesia on ventilation
and respiratory mechanics in man
POlHL-21584-02 0004 Respiratory mechanics in normal
and abnormal states • Effects of anesthesia on respiratory
mechanics (dogs)
** R23HL-21990-01 Accuracy of the ventilatory response to
exercise (dogs)
ROlHL-22022-01 Respiratory muscle dysfunction in
respiratory failure (human)
ROlHL-2255202 Abnormal alveolar permeability and lung
disease (sheep)
ROlHL-22622-01 Sleep apnea and desaturation-
mechanisms and incidence (human)
"* ROlHL-2264101 Ventilation, perfusion, and systemic
arterial reflexes (dogs)
" ROlHL'22843-01 Pulmonary physiology in liquid ventilation
(lambs)
ROlHL-22844-01 Phrenic nerve pacing-Noninvasive
diaphragm analysis (human, dogs)
ROlHL-22910-01 Control of breathing pattern in health
and disease (human, animals)
** R23HL-2293201 Effect of carbon dioxide on local gas
exchange (dogs)
** ROlHL-229 76-01 Nonuniform ventilation and diffusing
capacity (human)
ROlHL-23601-01 Early hypoxia and development of
respiratory control
** ROlHL-23985-01 Role of the diaphragm in regional lung
mechanics (dogs)
RESPIRATORY FUNCTION, RESPIRATION
SEE ALSO RESPIRATORY SYSTEM, COLLATERAL RESPIRATION
SEE ALSO RESPIRATORY SYSTEM REFLEXES
** ROlHL-02228-24 Respiration, circulation, and heat
regulation in exercise (bird, mammals)
** R01HL-02888-22 Interrelationships of circulation and
respiration (opossum, cats)
P01HL-04e64.18 0002 Cardiovascular and lung dynamics
■ X-ray cross section imaging of organs (dogs)
POlHL-04664-18 0003 Cardiovascular and lung dynamics
■ X-ray projection image vidcometry (human, dogs)
** POlHL-06285-18 0181 Cardiovascular-respiratory
physiology and biochemistry - Regulation of respiration-
Role of vagus nerve (dogs)
" P01HL-07896-15 0014 Environmental biomedical research
program - Mechanisms of respiration and circulation
(human, dogs)
** POlHL-07896-15 0033 Environmental biomedical research
program - Breathing mechanism in birds
** P01HL07896-15 0061 Environmental biomedical research
program - Oxygen cost of breathing during graded exercise
(human)
POlHL-08682-15 0037 Regulation of the cardiovascular
system - Central nervous regulation of cardiopulmonary
mechanisms (cats)
** POlHL-08805-15 0044 Regulation of ventilation and
pulmonary circulation - Neurochemical interactions in
respiratory control (human, dogs, goats)
" POlHL-08805-15 0045 Regulation of ventilation and
pulmonary circulation - Integrated description of
neurochemical respiratory control system
POlHL-08805-15 0046 Regulation of ventilation and
pulmonary circulation - Sites and modes of interaction of
peripheral and central chcmoreceptors
POlHL-08805-15 0047 Regulation of ventilation and
pulmonary circulation - Extracranial metabolic control of
ventilation (dogs, goats)
** POlHL-0889914 0015 Tolerance to respiratory gases in
health and disease - Respiratory adaptations to increases
in breathing (human)
*• POlHL-08899-14 0020 Tolerance to respiratory gases in
health and disease - Oxygen tolerance (human, rats.
guinea pigs)
POlHL-08899-14 0024
health and disease -
Tolerance to respiratory gases in
Effects of oxygen pressures on
physiological control systems (human, dogs)
POlHL-08899-14 0030 Tolerance to respiratory gases in
health and disease - Dynamic characteristics of respiratory
control components (human, cats)
POlHL-08899-14 0032 Tolerance to respiratory gases in
health and disease - Effects of high oxygen pressures upon
respiratory control
POIHL-08899-14 0034 Tolerance to respiratory gases in
health and disease - Hyperoxygenation and respiratory
response to acid-base stimuli (human, dog)
POlHL-08899-14 0036 Tolerance to respiratory gases in
health and disease - Chemical and neurogenic components
of respiratory simulation in exercise (human)
POlHL-08899-14 0041 Tolerance to respiratory gases in
health and disease - Blood gas transport and brain
circulatory control (human)
POlHL-10342-13 The integrated function of respiration
and circulation
POlHL-10342-13 0011 The integrated (unction of
respiration and circulation - Control of respiration 1-
Peripheral chemoreceptor studies (cats)
POlHL-10342-13 0014 The integrated function of
respiration and circulation - Oxygen and carbon monxide
transfer (human, dogs, sheep)
POlHL-10342-13 0026 The integrated function of
respiration and circulation - Control of respiration-
Characterization of the aortic body (cats)
POlHL-10342-13 0027 The integrated function of
respiration and circulation - Control of respiration -
Cardiovascular adjustment to hypoxia and carbon monoxide
POIHL 10436-13 0005 A multidisciplinary study of
congenital heart disease - Pulmonary physiology in
congenital heart disease (human)
POlHL-11678-11 0009 Cardiovascular dynamics and their
control - Control of respiration (cat, human)
ROIHL 12564-09
(human, dog)
ROlHL-13134-07
Control of respiration and blood gases
Mechanism of chemoreceptor discharge
Cardiorespiratory control in exercise
(cats)
R01HL13233-08
(human)
ROlHL-13841-16 Respiration during altitude
acclimatization (goats, dogs, rats, rabbits)
ROlHL-13888-15 Regulation of respiration
P50HL-14 153-07 0016 Johns Hopkins Lung Center -
Chronic diseases of airways - Airways defense mechanisms
(dogs)
POlHL-144 14-07 0007 Environmental influences on
cardiorespiratory and cellular functions - Neural control of
respiration (human, cats)
POlHL-1458007 0003 Program project in respiratory
mechanics - Chest wall mechanics and respiratory control
(human, dogs)
ROlHL-14870-06 Dynamics of oxygen and carbon dioxide
regulation (animals)
ROIHL-14903-07 A new index of cardiac contractility
(human, dogs, baboons)
POlHL-14985-07 0004 Adaptation to hypoxia - Control of
breathing in respiratory failure (human, dogs)
POlHL-14985-07 0009 Adaptation to hypoxia - Influence
of chemosensitivity on control of breathing during sleep
(human, dogs)
POlHL-15194-07 0023 Pathophysiology of
cardiopulmonary dysfunction - Distribution of ventilation-
Diffusion and cardiogenic agitation (dogs)
ROlHL-15526-05 Respiratoiy mechanics in children
ROlHL-15659-05 Dynamic isolation studies of control of
respiration (human)
ROlHL-16325-03 Breathing patterns in man
POlHL-16878-05 0001 Control of ventilation in health
and disease - Ability of asthmatics to detect added
resistive and elastic loads
ROlHL-173 14-04 Effects of anesthesia and loading on
respiration (human, cats)
P50HL-1 768204 0007 Study of ischemic heart disease -
Mechanisms of hypoxemia in myocardial infarction (human)
ROlHL-1768906 Neurophysiologic studies of respiratory
control (cats)
ROlHL-18007-05 Neural mechanisms controling motor act
of breathing (cats, human)
R0IHL18371-03 Pulmonary hypertension and ventilation
pathophysiology (dogs)
P50HL-191 55-02 0001 Pathophysiology of pulmonary
edema - Pulmonary edema study unit (human, dog)
P50HL-19187-02 0001 Pediatric pulmonary SCOR-Hyaline
membrane disease - Hyaline membrane disease-Changes
in lung mechanics and gas exchange (monkeys)
P50HL-191 90-02 0006 Pulmonary SCOR-Pathophysiology,
management of IRDS - Asphyxia-Respiratory control (dogs)
ROlHL-19248-03 Breathing pattern variation and
mechanical influences
ROlHL-1982702 Role of the upper airways in the control
of breathing (human, cats, dogs)
ROlHL-19829-02 Power output of breathing (human)
ROlHL-20328-01 Noninvasive assessment of autonomic
cardiac control (dogs)
ROlHL-20568-03
(rats)
ROlHL-20574-03
activity (cats)
R23HL-20576-01
exchange
ROlHL-20847-02
(human, goats)
ROlHL-20861-01
(dogs)
R23HL-21042-01
anatomical basi;
ROlHL-21257-02
Respiration during prolonged hypercapnia
Brain stem integration of chemoreceptor
Airway turbulence and pulmonary oxygen
Respiratory neurochemical control
Cardio-respiratory-renal stress reactions
Cardiopulmonary reflexes and their
(dogs)
Breathing in sleep-Airway control and
blood gases (cats)
ROlHL-22296-01 Autonomic mechanisms in man
ROlHL-22418-01 Neural control of cardiorespiratory
function (cats)
R13HL-22525-01 International symposium on the
diaphragm (Virginia)
ROlHL-22546-02 Baroreceptor reflex mechanisms in man
ROlHL-22622-01 Sleep apnea and desaturation-
mechanisms and incidence (human)
ROlHL-22910-01 Control of breathing pattern in health
and disease (human, animals)
R23HL-22920-01 Dynamic airway behavior (dogs)
NOlHR-32902-07 Pilot study to standardize the
measurement of closing volume (human)
RESPIRATORY FUNCTION, RESPIRATION,
THORACIC PRESSURE
ROlHL-1388508 9001 Cystic fibrosis and pulmonary
disease - Pulmonary function core facility (infants,
children)
RESPIRATORY FUNCTION, RESPIRATORY
AIRWAY CLEARANCE
** POlHL-06285-18 0189 Cardiovascular-respiratory
physiology and biochemistry - Mucociliary clearance (cats,
dogs)
** ROlHL-13596-07 Clearance of plasma proteins from
alveoli
P50HL-1415307 0016 Johns Hopkins Lung Center-
Chronic diseases of airways - Airways defense mechanisms
(dogs)
** ROlHL-18606-04 Pathogenesis and measurement of
pulmonary edema (human, rabbits, dogs)
P50HL-19156-02 0003 Pulmonary SCOR -Chronic diseases
of airways - Powdered tantalum to study airway morphology
and mucociliary clearance (human)
** P50HL 1915702 0003 Studies in cystic fibrosis and
bronchiolitis - Nasal mucosal function in patients with
cystic fibrosis
** P50HL-19170-02 0008 Harvard pulmonary SCOR-Chronic
diseases of the airways - Multiple-transient artificial
coughing (dogs, human)
P50HL-19190-02 0005 Pulmonary SCOR-Pathophysiology,
management of IRDS - Glycoproteins in mucous secretions
(human, cattle)
** ROlHL-19431-03 Regional mucociliary transport in the
human lung
** ROlHL-19975-02 Laryngeal biomechanics in pulmonary
therapy (primates)
ROlHL-21115-01
dismutase (rats)
** ROlHL-22928-01
(sheep)
NOlHR-62901-04
Prevention of 02 toxicity with superoxide
Systematic study of bronchial circulation
Measure pulmonary function in infants
'Excludes routine methodology OR rovers only general projects which preclude indexing at the specific level.
••Qfieflted significanthi to above subject.
and children (also dogs, rabbits)
RESPIRATORY FUNCTION, RESPIRATORY
AIRWAY PRESSURES
POlHL-06285-18 0181 Cardiovascular-respiratory
physiology and biochemistry - Regulation of respiration-
Role of vagus nerve (dogs)
POlHL-06285-18 0188 Cardiovascular-respiratory
physiology and biochemistry - Physiology and pharmacology
in regulation of airways-hyperirritability (animals)
ROlHL-08789-11 Respiratory muscles and ventilatory
control in man (and dogs)
POIHL-08805-15 0025 Regulation of ventilation and
pulmonary circulation - Pulmonary edema (rabbits)
POlHL-08805-15 0044 Regulation of ventilation and
pulmonary circulation - Neurochemical interactions in
respiratory control (human, dogs, goats)
POlHL-08899-14 0015 Tolerance to respiratory gases in
health and disease - Respiratory adaptations to increases
in breathing (human)
ROlHL-10009-13 Regional lung function in man
** POlHL-1034213 0006 The integrated function of
respiration and circulation ■ Lung inflation effects on
pulmonary vasculature and interstitial space (dogs)
POlHL-10342-13 0008 The integrated function of
respiration and circulation - Respiratory mechanics and the
circulation (human, dogs)
P01HL10342-13 0011 The integrated function of
respiration and circulation ■ Control of respiration 1-
Peripheral chemoreceptor studies (cats)
P50HL-14136-07 0001 Pulmonary SCOR-Airways
obstructive diseases - Experimental airway obstructive
disease (dogs)
P50HL-14136-07 0004
obstructive diseases -
emphysema (human)
P50HL-14136-07 0017
obstructive diseases -
(human)
P50HL-14153-07 0013 Johns Hopkins Lung Center-
Chronic diseases of airways ■ Pulmonary mechanics and
mediators of allergic reactions (guinea pigs, human)
P50HL-14153-07 0017 Johns Hopkins Lung Center-
Chronic diseases of airways - Collateral ventilation and
pulmonary interdependence (pig, dog, human)
P50HL-14153-07 0018 Johns Hopkins Lung Center-
Chronic diseases of airways - Pulmonary function core
P50HL-14214-07 0030 Newborn lung center for hyaline
membrane disease - Effects of ductal patency-Impedance
cardiography and echocardiography (human)
POlHL-14580-07 0001 Program project in respiratory
mechanics ■ Micromechanics of the lung (dogs, rats)
POlHL-14580-07 0002 Program project in respiratory
mechanics - Airway aerodynamics (human, dogs)
ROlHL-14854-07 Lung and tissue mechanics (monkeys,
dogs)
P50HL-15061-07 0004 Response of lung to injury ■
Biochemical abnormalities in connective tissues (rats)
POlHL-1519407 0024 Pathophysiology of
cardiopulmonary dysfunction - Distribution of ventilation-
Airflow limitation in COLD (human)
P50HL-15389-07 0016 Pulmonary SCOR-Hypersensitivity
pneumonitis - Pulmonary physiology core (human)
(contd)
Pulmonary SCOR-Airways
Morphometric studies of developing
Pulmonary SCOR-Airways
Pediatric airways obstructive disease
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
RES
Localliation ol llnwiys obsttuclion and
R0lHll64630b
rtsponsts
ROIHL'17314 04 Ettects ol anesthesia and loadinii on
rtspifilion (human, cats)
ROIHL 17358 04 Ventilatory adiustments loi optimal
onygenation (dogs, lats)
P50HL l/66b04 0003 Study of ischemic heart disease
Caidiopulmonaiy resuscitation (human, dog)
ROIHI 17944 03 Studies in lung preservation (dogs)
ROIHL 1860604 Pathogenesis and measurement ot
pulmonary edema (human, rabbits, dogs)
ROIHL 19118 03 Measurement ol airways mechanics
(human, dog)
P50HL 191S602 0001 Pulmonary SCOR Chronic diseases
ol airways Irritability ot airways induced by epithelial
damage in healthy subjects (human)
PSOHL 19157 02 0003 Studies in cystic fibrosis and
bronchiolitis Nasal mucosal function in patients with
cystic fibrosis
P50HL 19170-02 0006 Harvard pulmonary SCOR-Chronic
diseases of the airways Mechanism of overdistension
(human, animal)
P50HL1918702 0001 Pediatric pulmonary SCOR Hyaline
membrane disease Hyaline membrane disease-Changes
in lung mechanics and gas exchange (monkeys)
P50HL 19187 02 0002 Pediatric pulmonary SCOR Hyaline
membrane disease Hyaline membrane disease-Alterations
in surface active material (monkeys)
P50HL-1919002 0009 Pulmonary SCOR-Pathopliysiology,
management of IRDS Developing non-invasive neonatal
pulmonary monitoring systems (rabbit, human)
P50HL 19362-02 0008 A/S SCOR Atherosclerosis in
nonhuman primates Lung structure and function in
cigarette smoking (baboon)
POlHL-19717-02 0018 Response of the lung to injury -
Lung mechanics and connective tissue composition in
human emphysema
** ROlHL-19829-02 Power output of breathing (human)
ROlHL-20568-03 Respiration during prolonged hypercapnia
(rats)
** ROlHL-20652-01 Sites of leakage in pulmonary edema
(dogs)
ROlHL-20773-02 Surfactant, pulmonary edema, and lung
mechanics (rabbits)
ROlHL-20783-02 Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
R23HL-2096802 Respiratory failure -Control and muscle
dysfunction (human)
ROlHL-20989-01
(sheep, dogs)
R23HL-21050-02
edema (rabbits)
ROlHL-21115-01
dismutase (rats)
ROlHL-21257-02
blood gases (cats)
R23HL-21405-01 Respiratory muscles in regulation of
Infant breathing (human)
ROlHL-21444-02 Pulmonary mechanics during postnatal
development (human)
M POlHL-21584-02 Respiratory mechanics in normal and
abnormal states
POlHL-21584-02 0001 Respiratory mechanics in normal
and abnormal states - Engineering analysis of lung
deformation (human, animals)
POlHL-21584-02 0002 Respiratory mechanics in normal
and abnormal states - Lung mechanics-Regional
deformation and ventilation (dogs)
POlHL-21584-02 0006 Respiratory mechanics in normal
and abnormal states - Respiratory mechanics in health and
disease (human, pigs)
ROlHL-22313-01 Lung elastic recoil -Age and disease
(human)
ROlHL-22446-01 Chemical and functional studies of low
copper in lung (pigs)
ROlHL-22723-01 The morphologic basis of airflow
obstruction (human)
ROlHL-22843-01 Pulmonary physiology in liquid ventilation
(lambs)
** R23HL-22920-01 Dynamic airway behavior (dogs)
ROlHL-23985-01 Role of the diaphragm in regional lung
mechanics (dogs)
NOlHR-62910-02 Fibroprotein networks of pulmonary
alveolar wall (human)
RESPIRATORY FUNCTION, RESPIRATORY
AIRWAY VOLUME
POlHL-04664-18 0002 Cardiovascular and lung dynamics
- X-ray cross section imaging of organs (dogs)
POlHL-04664-18 0016 Cardiovascular and lung dynamics
- Computerized roentgenographic determination of total
lung capacity
POlHL-06285-18 0181 Cardiovascular-respiratory
physiology and biochemistry - Regulation of respiration-
Role of vagus nerve (dogs)
** POlHL-06296-18 0002 Cardiovascular and pulmonary
adaptation to stress - Respiratory muscle blood flow,
mechanics and metabolism (human, dog)
POlHL-07896-15 0009 Environmental biomedical research
program - Decompression sickness and computation of safe
diving tables (human, animals)
Pathophysiology of bronchial asthma
Mechanisms of re-expansion pulmonary
Prevention of 02 toxicity with superoxide
Breathing in sleep -Airway control and
475
POIHl 0/896 15 0014 Environmental biomedical research
piogram Mechanisms ol rospiialion and cicculation
(human, dogs)
POIHL 0/896 15 0058 Environmental biomedical research
program Lung synthesis ol disaturated
phosphatidylcholine (rats. dogs, bats)
POIHL 08805 15 0044 Regulation of ventilation and
pulmonary circulation Neurochemical interactions in
respiratory control (human, dogs, goats)
POIHL 08805 15 0045 Regulation of ventilation and
pulmonary circulation Integrated description of
neurochemical respiratory control system
POIHL 08899 14 0031 Tolerance to respiratory gases in
health and disease Studies in exercise (human, dogs)
ROIHL 10009 13 Regional lung function in man
POIHL 10342 13 0006 The integrated function of
respiration and circulation Lung inflation effects on
pulmonary vasculature and interstitial space (dogs)
POIHL 10342 13 0008 The integrated function of
respiration and circulation Respiratory mechanics and the
circulation (human, dogs)
POIHL 10436 13 0005 A multidisciplinary study of
congenital heart disease Pulmonary physiology in
congenital heart disease (human)
ROIHL 10622 12 Volumes and compliance of pulmonary
circulation (human, dogs)
ROIHL 11907-08 Mechanisms of physiological responses
to exercise (human, dogs)
ROIHL 13172-10 Post-trauma lung mechanics and fluid
exchange (human, dogs, monkeys)
ROIHL 13885-08 9001 Cystic fibrosis and pulmonary
disease - Pulmonary function core facility (infants.
children)
Pulmonary SCOR -Airways
Experimental airway obstructive
P50HL-14136-07 0001
obstructive diseases
disease (dogs)
P50HL-14136-07 0004
obstructive diseases
emphysema (human)
P50HL-14136-07 0005
obstructive diseases
Pulmonary SCOR -Airways
Morphometric studies of developing
Pulmonary SCOR -Airways
Radiographic studies of airways
obstructive disease (human)
P50HL-14 153-07 0013 Johns Hopkins Lung Center-
Chronic diseases of airways - Pulmonary mechanics and
mediators of allergic reactions (guinea pigs, human)
P50HL-14153-07 0017 Johns Hopkins Lung Center-
Chronic diseases of airways - Collateral ventilation and
pulmonary interdependence (pig. dog. human)
P50HL-14153-07 0018 Johns Hopkins Lung Center-
Chronic diseases of airways - Pulmonary function core
P50HL-142 14-07 0030 Newborn lung center for hyaline
membrane disease - Effects of ductal patency -Impedance
cardiography and echocardiography (human)
POlHL-14580-07 0001 Program project in respiratory
mechanics - Micromechanics of the lung (dogs, rats)
POlHL-14580-07 0003 Program project in respiratory
mechanics - Chest wall mechanics and respiratory control
(human, dogs)
POlHL-14580-07 0005 Program project in respiratory
mechanics - Development and evaluation of tests of
pulmonary function (human)
ROlHL-14854-07 Lung and tissue mechanics (monkeys,
dogs)
ROlHL-14967-06 Chemoreceptor function in dynamic
ventilatory control (human, dogs)
P60HL-15 160-07 0015 Center for sickle cell disease -
Lung function abnormalities in sickle cell
hemoglobinopathies (human)
POlHL-15194-07 0009 Pathophysiology of
cardiopulmonary dysfunction - Kinetics of gas exchange-
Diffusion and erythrocytes reaction rates (human, dogs)
POlHL-15194-07 0011 Pathophysiology of
cardiopulmonary dysfunction - Distribution of ventilation-
Oxygen effects on intrapulmonary shunting (human)
POlHL-15194-07 0022 Pathophysiology of
cardiopulmonary dysfunction - Kinetics of gas exchange-
Pulmonary carbon dioxide exchange (dogs)
POlHL-15194-07 0023 Pathophysiology of
cardiopulmonary dysfunction - Distribution of ventilation-
Diffusion and cardiogenic agitation (dogs)
POlHL-15194-07 0024 Pathophysiology of
cardiopulmonary dysfunction - Distribution of ventilation-
Airflow limitation in COLD (human)
P50HL-15389-07 0016 Pulmonary SCOR-Hypersensitivity
pneumonitis - Pulmonary physiology core (human)
ROlHL-15430-05 Cardiopulmonary adaptation of newborns
to altitude (human)
ROlHL-15526-05 Respiratory mechanics in children
ROlHL-16463-05 Localization of airways obstruction and
responses
ROlHL-16784-03
dogs)
POlHL-16878-05 0001 Control of ventilation in health
and disease - Ability of asthmatics to detect added
resistive and elastic loads
ROlHL-173 14-04 Effects of anesthesia and loading on
respiration (human, cats)
ROlHL-17355-04 Pulmonary vascular adjustments in
circulatory collapse (dogs, rats)
ROlHL-17543-03 0001 Magnetic tracers for diagnosis of
lung disease - Chronic, interstitial lung disease (human,
rabbits)
Lung tissue and water volume (human.
RES
P50HI 17655 04 0003 Study of iKhamic htirt diMiu
Cardiopulmonary resuscitation (human, ilo|)
NO I HI 1/689 06 Neurophysiologic studies of ritpititory
control (cats)
POIHl 17/31 04 0001 Physiological basis ol pulmonary
disease Mechanisms ol blood flow and ventilation (dogs)
POIHL 17/31 04 0003 Physiological basis of pulmonary
disease Comparative physiology (vertebrates)
ROIHL 1/768 04 Development of collateral ventilation
(dogs. fish, horses)
POIHL 1/81304 0001 Lung disease and the oxygenation
of blood and tissue Diffuse interstitial lung disease
Pathophysiology (human, dogs)
POIHL 17813 04 0006 Lung disease and the oxygenation
of blood and tissue Assessment of respiratory muscle
contractile force (human, dogs)
ROIHL 18351 03 Brain metabolism, acid base balance,
and respiration
ROIHL 18606 04 Pathogenesis and measurement of
pulmonary edema (human, rabbits, dogs)
P50HL 19155-02 0001 Pathophysiology of pulmonary
edema Pulmonary edema study unit (human, dog)
P50HL 19156 02 0003 Pulmonary SCOR Chronic diseases
of airways Powdered tantalum to study airway morphology
and mucociliary clearance (human)
P50HL-19170 02 0001 Harvard pulmonary SCOR Chronic
diseases of the airways Natural history, reversibility of
pulmonary abnormalities in smokers (human)
P50HL 19170 02 0003 Harvard pulmonary SCOR- Chronic
diseases of the airways Mechanisms of bronchial
reactivity to acute and chronic airway challenge (dog)
■ P50HL-19170-02 0006 Harvard pulmonary SCOR Chronic
diseases of the airways Mechanism of overdistension
(human, animal)
P50HL 19185 02 0004 Pulmonary SCOR-Neonatal
respiratory distress syndromes Fluid and protein transport
in fetal and newborn lung (sheep, rabbits)
P50HL-19185-02 0009 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Nasal continuous positive
airway pressure in hyaline membrane disease (human)
P50HL-19187-02 0001 Pediatric pulmonary SCOR-Hyaline
membrane disease - Hyaline membrane disease -Changes
in lung mechanics and gas exchange (monkeys)
P50HL-19187-02 0002 Pediatric pulmonary SCOR-Hyaline
membrane disease - Hyaline membrane disease -Alterations
in surface active material (monkeys)
P50HL-19 190-02 0006 Pulmonary SCOR-Pathophysiology,
management of IRDS - Asphyxia-Respiratory control (dogs)
P50HL-19190-02 0009 Pulmonary SCOR-Pathophysiology,
management of IRDS - Developing non-invasive neonatal
pulmonary monitoring systems (rabbit, human)
ROlHL-19298-03 Pulmonary hemodynamics (dogs, cats)
P50HL-19362-02 0008 A/S SCOR -Atherosclerosis in
nonhuman primates - Lung structure and function in
cigarette smoking (baboon)
ROlHL-19449-03 Gas exchange in acute respiratory failure
* POlHL-19717-02 0011 Response of the lung to injury ■
Physiological characterization of the elastase model
(hamsters)
POlHL-19717-02 0018 Response of the lung to injury -
Lung mechanics and connective tissue composition in
human emphysema
Power output of breathing (human)
Regulation of protein turnover in lung
Respiration during prolonged hypercapnia
Airway turbulence and pulmonary oxygen
Sites of leakage in pulmonary edema
ROlHL-19829-02
ROlHL-20344-02
tissue (rats)
ROlHL-20568-03
(rats)
R23HL-20576-01
exchange
ROlHL-20652-01
(dogs)
ROlHL-20875-02 Chronic obstructive pulmonary disease-
Familial/genetic (human)
R23HL-20968-02 Respiratory failure-Control and muscle
dysfunction (human)
ROlHL-20989-01
(sheep, dogs)
ROlHL-21117-01
Pathophysiology of bronchial asthma
Altitude adaptation in chronic lung
disease (human)
R23HL-21 168-01 Hypoxemic respiratory failure-Physiologic
evaluation (human, dogs)
R23HL-21405-01 Respiratory muscles in regulation of
infant breathing (human)
ROlHL-21444-02 Pulmonary mechanics during postnatal
development (human)
POlHL-21584-02 Respiratory mechanics in normal and
abnormal states
POlHL-2 1584-02 0001 Respiratory mechanics in normal
and abnormal states - Engineering analysis of lung
deformation (human, animals)
POlHL-2 1584-02 0002 Respiratory mechanics in normal
and abnormal states - Lung mechanics-Regional
deformation and ventilation (dogs)
POlHL-2 1584-02 0003 Respiratory mechanics in normal
and abnormal states - Effects of anesthesia on ventilation
and respiratory mechanics in man
POlHL-2 1584-02 0004 Respiratory mechanics in normal
and abnormal states - Effects of anesthesia on respiratory
mechanics (dogs)
POlHL-21584-02 0006
and abnormal states -
disease (human, pigs)
Respiratory mechanics in normal
Respiratory mechanics In health and
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject.
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
RES
R23HL-21943-01 Capillary morphology In pulmonaiy
edema (dogs)
ROlHL-21948-01 Capillaty, tissue volume and lymph flow
in lung edema (sheep, cattle)
ROlHL-22022-01 Respiratoiy muscle dysfunction in
respiratory failure (human)
** ROlHL-22178-01 Lung airway properties by acoustic
impulse reflection
ROlHL-22313-01 Lung elastic recoil-Age and disease
(human)
ROlHL-22415-01 Mechanisms responsible for disease
severity in asthma (human)
ROlHL-22446-01 Chemical and functional studies of low
copper in lung (pigs)
ROlHL-2262201 Sleep apnea and desaturation-
mechanisms and incidence (human)
ROlHL-22723-01 The morphologic basis of airflow
obstruction (human)
ROlHL-2284401 Phrenic nerve pacing-Noninvasive
diaphragm analysis (human, dogs)
** ROlHL-2291001 Control of breathing pattern In health
and disease (human, animals)
" R23HL-22920-01 Dynamic airway behavior (dogs)
** R23HL-22933-01 Transvascular fluid and protein exchange
in the lung (sheep)
ROlHL-23015-01 Mechanisms of hypo-oncotic pulmonary
edema (human, dogs)
ROlHL-2398101 Acute alveolar injury (dogs)
ROlHL-23985-01 Role of the diaphragm in regional lung
mechanics (dogs)
** NOlHR-32900-09 Pilot study to standardize the
measurement of 'closing volume' (human)
•* NOlHR-32902-07 Pilot study to standardize the
measurement of closing volume (human)
NOlHR-32903-11 Pilot study to standardize the
measurement of closing volume' (human)
NOlHR-6290104 Measure pulmonary function in infants
and children (also dogs, rabbits)
NOlHR-62910-02 Fibroprotein networks of pulmonary
alveolar wall (human)
RESPIRATORY FUNCTION, VALSALVA'S
MANEUVER
P50HL-19170-02 0008 Harvard pulmonary SCOR-Chronic
diseases of the airways - Multiple-transient artificial
coughing (dogs, human)
ROlHL-19827-02 Role of the upper airways in the control
of breathing (human, cats, dogs)
R01HL-225G6-01 Hemodynamics of the clinical
hypertensions
RESPIRATORY GAS ANALYZERS*
** P50HL-14218-07 0013 Pulmonary SCOR-Newborn lung
center - Longitudinal study of RDS -Monitoring fetal P02
and PC02 during labor (human)
ROlHL-17358-04 Ventilatory adjustments for optimal
oxygenation (dogs, rats)
POlHL-17731-04 0006 Physiological basis of pulmonary
disease - Ventilalion-perfusion ratios (human, dogs)
P50HL-19187-02 0009 Pediatric pulmonary SCOR-Hyaline
membrane disease - Non-invasive measurement and
monitoring of arterial oxygen tension (dogs, sheep)
" ROlHL-20351-02 A self-calibrating in vivo blood gas
monitor (dogs, infants)
ROlHL-22636-01 Newborn lung function during
mechanical ventilation (human)
RESPIRATORY GAS ANALYZERS, OXIMETRY*
SEE ALSO HEART DISORDERS DIAGNOSIS. FICK METHOD*
** R01HL-18710-02 Non-invasive reflection oximetry in
peripheral tissue (dogs)
RESPIRATORY GAS CONSUMPTION, OXYGEN
CONSUMPTION
ROlHL-02228-24 Respiration, circulation, and heat
regulation in exercise (bird, mammals)
R01HL03181-21 0025 Hemodynamics as applied to
surgical problems - Vascular stenosis (dogs)
ROIHL-05806-18 Analysis of antiarrhythmic agents (dogs,
rabbits)
** R01HL05883-I8 0008 Reflex control of resistance and
capacitance vessels - Oxygen consumption of the
chronically dcnervated dog heart
** POlHL-06285-18 0134 Cardiovascular-respiratory
physiology and biochemistry - Placental transfer in growth
retarded fetuses (lambs)
POlHL-07896-15 0009 Environmental biomedical research
program - Decompression sickness and computation of safe
diving tables (human, animals)
POlHL-07896-15 0048 Environmental biomedical research
program Respiratory performance in divers at 1400 FSW
POlHL-07896-15 0050 Environmental biomedical research
program - Fundamental decompression concepts using the
rat animal model
POlHL-07896-15 0052 Environmental biomedical research
program - Effects of hypoxia on cerebral function
POlHL-07896-15 0058 Environmental biomedical research
program - Lung synthesis of disaturated
phosphatidylcholine (rats, dogs, bats)
" POlHL-0789615 0061 Environmental biomedical research
program ■ Oxygen cost of breathing during graded exercise
(human)
476
POlHL-0789615 0063 Environmental biomedical research
program - Oxygen toxicity (baboons)
ROlHL-08659-14 Myocardial performance and metabolism
in the newborn (sheep)
POlHL-0880515 0047 Regulation of ventilation and
pulmonary circulation - Extracranial metabolic control of
ventilation (dogs, goats)
POlHL-10436-13 0002 A multidisciplinary study of
congenital heart disease - Myocardial performance,
metabolism and ultrastructure (human, cats, rats)
POlHL-10539 12 0064 Pathophysiology of circulation -
Exercise physiology and pathophysiology (human)
POIHL 10539-12 0065 Pathophysiology of circulation ■
Physiologic correlates of relaxation (human)
POlHL-10539-12 0068 Pathophysiology of circulation ■
Acute and chronic cardiomyopathies (mice, dogs hamsters,
human)
R01HL'10e22'12 Volumes and compliance of pulmonary
circulation (human, dogs)
POlHL-11310-12 0068 Mechanisms of cardiovascular
disease - Pharmacological intervention and myocarcial
oxygen consuption (human, dogs)
POlHL-1135112 0006 Cellular and molecular
mechanisms of myocardial function ■ Molecular physiology
and energetics of muscle (frogs)
P01HL11351-12 0021 Cellular and molecular
mechanisms of myocardial function - Muscle energetics
(frogs)
POlHL-11351-12 0022 Cellular and molecular
mechanisms of myocardial function • Energetic sequelae of
shortening -Myothermal and biochemical (frogs)
POlHL-11351-12 0023 Cellular and molecular
mechanisms of myocardial function - Energetics of
mammalian muscle (rats)
ROlHL-11945-10 Synthesis of artificial lung and kidney
systems (sheep, mice, swine)
ROlHL-12322-10 Extrinsic factors influencing myocardial
performance (dogs, swine)
POlHL-12373-10 0003 Cardiopulmonary physiology and
pathophysiology - Myocardial function in man
P01HL-12738I0 0069 Physiologic pharmacology and its
clinical applications - Blood rheology in coronary heart
disease (dogs)
POlHL-12738-10 0122 Physiologic pharmacology and its
clinical applications - Coronary perfusion of beating and
fibrillating hearts (dogs)
ROlHL-12777-09 Mechanisms in cardiac performance
(dogs, human)
ROlHL-12997-07 Myocardial defects induced by potassium
depletion (human, rats, cats)
P01HL-13108-09 0020 Clinical heart transplantation -
Autonomic neural studies in the denervated heart (human)
ROlHL-13257-09 Inhalation anesthesia on myocardial
metabolism (dogs, swine, human)
POlHL-13330-08 0059 Mechanical circulatory support ■
Physiologic evaluation of circulatory assistance (cattle)
ROlHL-13634-08 Renal hypertension in pregnancy (sheep)
P01HL13737-07 0027 Assisted circulation - Optimization
of cardiac assistance (dogs)
ROlHL-1392107 The lung as a metabolic organ (animals)
P50HL-141 87-07 0015 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses -
Pathophysiologic responses of pulmonary capillary bed
(dog, human)
P50HL-142 17-08 0057 Specialized center of research in
thrombosis - Pharmacology-Platelet biochemistry (human,
animal)
Regulation of the circulation in
Energetics of smooth muscle
Regulation of the circulation in
Pharmacology of the coronary
POlHL-14388-07 0154
pathological states
contraction (rats)
POlHL-14388-07 0220
pathological states
circulation in man
ROlHL-14644-05 Optimization diastolic augmentation and
systolic sink (dogs)
ROlHL-14693-07 Survival value of physiological responses
to hypoxia (dogs)
POlHL-14985-07 0008 Adaptation to hypoxia ■ Ventilatory
drive and exercise capacity (human, dogs)
ROlHL-15231-05 Mechanisms of hemodynamic changes
during digestion (dogs)
ROlHL-15655-05 Blood flow and gas exchange in placenta
and lungs (sheep) rabbits)
P01HL15835-06 0018 Study of muscles related to heart
disease - Pharmacology of excitation coupling in muscle
(frog, barnaclei)
ROlHL-15983-04 Regional myocardial blood flow (dogs)
ROlHL-16292-05 0002 Surgery and nonobstructive
coronary insufficiency ■ Effects of hypothermia during
cardiopulmonary bypass (dogs)
ROlHL-16292-05 0009 Surgery and non-obstructive
coronary insufficiency - Exercise and supply-demand
balance (human)
ROlHL-16292-05 0018 Surgery and non-obstructive
coronary insufficiency - Unavoidable subendocardial
perfusion caused by venting and hypothermia (dogs)
ROlHL-16292-05 0019 Surgery and non-obstructive
coronary insufficiency - Distortion of subendocardial vessels
in infant hearts (dogs)
ROlHL-16656-06 Left ventricular function in exercise
(dogs)
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
••Onented significantly to above subject.
RES
ROlHL-16760-05 Dynamic control of coronary blood flow
(dogs)
POlHL-16851-04 0009 Human red cell membrane in
health and disease - Blood cell properties in circulatory
regulation (dogs, rabbits)
POlHL-16910-05 0002 Regulation of the peripheral
circulation - Coronary circulation (dogs)
POlHL-16910-05 0007 Regulation of the peripheral
circulation - CNS -Behavioral influences on circulation
(baboons)
ROlHL-17358-04 Ventilatory adjustments for optimal
oxygenation (dogs, rats)
ROlHL-1740303 Metabolic control of cardiac output
(dogs)
R0IHL17459-03 Myocardial ischemia (dogs)
ROlHL-17628-03 Pulsatile pressure-flow dynamics (dogs)
P50HL-I7665-04 0026 Study of Ischemic heart disease -
Anesthesia -Myocardial ischemia and hemodynamics in
coronary disease (human)
P50HL-17667-04 0012 Study of ischemic heart disease -
Biochemistry of normal and ischemic heart -Glycolysis (rats)
P50HL-17670-04 0022 Study of ischemic heart disease -
Myocardial metabolism in hypoxia and recover (rabbit,
toad, dog)
P50HL 17682-04 0005 Study of Ischemic heart disease -
Regional myocardial perfusion deficits and segmental
contraction disorders in man
P50HL-1 7682-04 0018 Study of ischemic heart disease -
Biochemistry of ischemia-Heart cell and organ culture
(mice, rats, cattle)
ROlHL-17736-04 Metabolic change during cardiac
ischemia (rats, dogs)
R01HL17808-03 Effect of altered oxygen affinity on
oxygen transport (human, rats)
POlHL-1781304 0007 Lung disease and the oxygenation
of blood and tissue - Studies on the function of myoglobin
(dogs)
ROlHL-17932-04 Blood flow regulation in muscle (cats)
ROlHL-17967-04 Limiting factors in oxygen uptake in the
lung
POlHL-18708-03 0009 Oxygen, energy and contractility in
cardiac tissue - Regulation of oxygen utilization of cardiac
tissue (rats, rabbits)
POlHL-18708-03 0010 Oxygen, energy and contractility in
cardiac tissue - Tissue oxygen utilization (rats, dogs)
ROlHL-18933-03 Energy output and efficiency of left
ventricle (dog)
ROlHL-18976-03 Blood pressure control-Relation to
behavioral stress (human, dog)
P50HL-19170-02 0004 Harvard pulmonary SCOR-Chronic
diseases of the airways - Exercise, increased ventilation
effect on airway exposure and responses (rodent)
P50HL-19190-02 0007 Pulmonary SCOR-Pathophysiology.
management of IRDS - Asphyxia-Cerebral metabolism (dog.
rat)
R01HL19299-03 Myoglobin and oxygen supply to heart
and muscle cells (rats, pigeons)
ROlHL-19461-03 Myocardial energetics in hypertrophy and
heart failure (rabbits)
POlHL-19737-02 0006 Cellular and molecular aspects of
respiratory physiology - Tissue oxygenation and
mitochondrial respiratory activity (sheep)
ROlHL-20080-02 Surgically induced myocardial edema
(dogs)
ROlHL-20226-02 Cardiac bypass and coronary collateral
physiology (dogs)
ROlHL-20286-02 Interventions to improve cardiac function
in ischemia (dogs)
ROlHL-20388-03 Regulation of protein turnover in diabetic
heart (rat)
ROlHL-20401-03 Relationship of insulin to catechol
cardiomyopathy (rabbit, pig)
ROlHL-20476-03 Effects of diabetes on cardiac
performance (rat)
ROlHL-20484-03 Effects of diabetes on cardiac function
and metabolism (rats)
POlHL-20552-02 0002 The development and regression of
cardiac hypertrophy - Effect of treatment on the
hypertrophied left ventricle (rats)
ROIHL 20607-02 Tissue analysis by mass spectrometer
(dogs)
ROlHL-2072002 Myocardial protection during
cardiopulmonary bypass (dogs)
ROlHL-20782-01 Coronary flow regulation by adenosine
(rats, dogs)
ROlHL-20861-01 Cardio-respiratory-renal stress reactions
(dogs)
P60HL-20985-01 0006 Northern California sickle cell
center - Antisickling properties of imidoesters (human, rats)
R23HL-2I 168-01 Hypoxemic respiratory failure-Physiologic
evaluation (human, dogs)
ROlHL-21 172-02 Regional oxygen consumption of heart
and other organs (animals)
ROlHL-21245-02 Influence of chronic exercise on
hypertension (rats, primates)
R23HL-21393-01 Cardiac adaptation to aging and stress
(rats)
R23HL-21396-02 Isolation, growth and metabolism of type
1 pneumocytes (rabbits)
ROlHL-21482-01 Cardiac function and metabolism in
diabetes (rats)
(contd)
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
RES
477
P«t1otm«nce ot respnatory muscles under
The mechanical basis o( myocacdial
ROIHL 21500 02
stress (dogs)
R01H121S7O01
enei|«lics (cats)
R23HL 2178301 Ionic control ot contractility in anoxic
myocaidiuffl (labbits. rats)
ROIHL 21851 01 Cerebral microcirculation in experimental
hypertension (cats, rabbits)
R23HL 21990 01 Accuracy ol the ventilatory response to
exercise (dots)
ROIHL 2215401
(dog)
ROIHL 2231501
Cardiopulmonary control coupling in
Computer
Cardiac adaptation to physical training
Intraoperative cardiac oxygen supply
demand (dogs, rabbits, rats)
ROIHL 2232901 Active prosthetic myocardium -Eflects on
LV tunction (dogs)
•• ROIHL 22517 01 Engineering development ot an ultrasonic
ventilometer (human)
R23HL 2257501 Factors modifying cardiac digoxin effects
and content (dogs, cats)
** POIHL 2261901 0010 Cellular mechanisms of heart
failure Mitochondria in heart and smooth muscle (rabbits.
rats, dogs)
R23HL22621 01 Blood cell-mediated pulmonary (human)
ROlHL-2266101 Chronic total cardiopulhonary mechanical
substitution (sheep)
ROlHL-2282801 Adenosine and catecholamine interaction
in the heart (rats)
ROIHL 2316601 Pathology of mitochondria in ischemic
myocardium (rats, cattle)
R01HL-2320501 Contraction of pulmonary vascular
smooth muscle (cat)
ROlHL'23206-01 Repetitive exercise and cardiac
enlargement (dogs)
ROlHL-2324001 Pulmonary vascular muscle metabolism
and contractility (rats, cattle)
RESPIRATORY GAS LEVELS
SEE ALSO ENVIRONMENTAL CHAMBER CONTROLLED,
HYPERBARIC FACILITY
SEE ALSO INJURIES. OYSBARISM
SEE ALSO RESPIRATORY GAS ANALYZERS*
P01HL0628518 0136 Cardiovascular-respiratory
physiology and biochemistry - Fetal microcirculation in
utero (rabbits, lambs)
POlHL-07896-15 0009 Environmental biomedical research
program - Decompression sickness and computation of safe
diving tables (human, animals)
POlHL-0789615 0033 Environmental biomedical research
program - Breathing mechanism in birds
POlHL-08682-15 0038 Regulation of the cardiovascular
system - Control of pulmonary circulation (dogs)
M POlHL-08805-15 Regulation of ventilation and pulmonary
circulation
POlHL-08805-15 0045 Regulation of ventilation and
pulmonary circulation - Integrated description of
neurochemical respiratory control system
POlHL-08899-14 0029 Tolerance to respiratory gases in
health and disease - Isobaric gas counter diffusion
phenomena (human, pigs)
** POlHL-08899-14 0040 Tolerance to respiratory gases in
health and disease - Metabolic gas influence on brain
vascular tissue (animals)
** POlHL-08899-14 0041 Tolerance to respiratory gases in
health and disease - Blood gas transport and brain
circulatory control (human)
POlHL-08899-14 0052 Tolerance to respiratory gases in
health and disease - Oxygen effects on auditory and
vestibular function (human, guinea pigs)
POlHL-08899-14 0074 Tolerance to respiratory gases in
health and disease - Biomathematical analysis of isobaric
gas exchange and bubble formation
ROlHL-09609-11 Lung volume and breathing mechanics
during anesthesia (human)
ROlHL-12174-n Ventilation/perfusion distribution in the
lung (human, mammals)
R01HL-12530-10 Emphysema-Respiratory function in
disease (human, dogs, rats)
ROlHL-12564-09 Control of respiration and blood gases
(human, dog)
ROlHL-12614-09 Microcirculatory control mechanisms and
hypertension (bats, rats)
R01HL13233-08 Cardiorespiratory control in exercise
(human)
ROlHL-13341-06 Lymph-An indication of splanchnic tissue
respiration (dogs, human, rats)
POlHL-14414-07 0003 Environmental influences on
cardiorespiratory and cellular functions - Exposure to
abnormal gaseous environments (human, dogs, rabbits)
** POlHL-14414-07 0008 Environmental influences on
cardiorespiratory and cellular functions - Energetics of
swimming (human)
ROlHL-14495-05 Solid and structural mechanics of lungs
(mammals)
P01HL-14985-07 0015 Adaptation to hypoxia - Pregnancy
at high altitude (human, animals)
P01HL-14985-07 0017 Adaptation to hypoxia - Core
laboratories
R01HL-15659-05 Dynamic isolation studies of control of
respiration (human)
ROlHL-16254-05 Pathogenesis of bubble and clot
formation (fish)
ROIHI 1639005
exercise (dogs)
P60HL 17292 04 0029 Vermont lung Center
assisted preoperative evaluation (human)
P60HI 17292 04 0031 Vermont Lung Center Regional
respiratory computer network
ROIHL 1735504 Pulmonary vascular adjustments in
circulatory collapse (dogs, rats)
ROIHL 17358 04 Ventilatory adjustments for optimal
oxygenation (dogs, rats)
R01HL17503-03 Vascular bubbles in decompression
sickness (minipig, dog, goat)
ROIHL 17578 04 Exercise performance in children with
heart disease
P50HL- 17655-04 0003 Study of ischemic heart disease
Cardiopulmonary resuscitation (human, dog)
P50HL 17655-04 0014 Study of ischemic heart disease
Blood flow and gas tension in myocardial ischemia and
infarction (dog, monkey)
P50HL 17667-04 0039 Study of ischemic heart disease
Core human investigative laboratories
ROlHL-1776804 Development of collateral ventilation
(dogs, fish, horses)
ROIHL 18022-03 Role of multicomponent diffusion in gas
exchange (avian eggs)
ROIHL 18371-03 Pulmonary hypertension and ventilation
pathophysiology (dogs)
ROlHL-18762 03 Posttraumatic pulmonary insufficiency
(dogs)
P50HL-19185-02 0009 Pulmonary SCOR -Neonatal
respiratory distress syndromes Nasal continuous positive
airway pressure in hyaline membrane disease (human)
* ROlHL-19352-03 Respiratory heat and water loss in
neonates
ROIHL 19410-03 Dynamic interrelations underlying
exercise hyperpnea (human)
* POlHL-19737-02 0005 Cellular and molecular aspects of
respiratory physiology - Interaction of respiratory exchanges
and blood gas parameters (human, animals)
* POlHL-19737-02 0011 Cellular and molecular aspects ot
respiratory physiology - Chemical and metabolic factors on
peripheral chemoreceptor activity (cats)
* R01HL20607-02 Tissue analysis by mass spectrometer
(dogs)
POlHL-20994-02 0009 Dynamics of neutrophil elastase in
the lung - Biosynthesis and degradation of elastin in
emphysema (human, hamsters)
R23HL-2 1539-02 Mechanical properties of isolated small
bronchioles (rabbits)
R23HL-21943-01
edema (dogs)
ROlHL-22327-01
skin (swine)
R01HL-22636-01
mechanical ventilation (human
ROlHL-227 15-01
reflexes (dogs))
ROlHL-22843-01
(lambs)
ROlHL-23239-01
Capillary morphology in pulmonary
Transport of arterial blood gases through
Newborn lung function during
ition (human)
Neural integration of the cardiovascular
Pulmonary physiology in liquid ventilation
Functional characteristics of pulmonary
vascular smooth muscle (dogs)
RESPIRATORY GAS LEVELS, BOHR EFFECT
ROlHL-12174-11 Ventilation/perfusion distribution in the
lung (human, mammals)
ROlHL-13531-06 Coboglobins -Cobalt substituted myo- and
hemoglobins
POlHL-14414-07 0014 Environmental influences on
cardiorespiratory and cellular functions - Temperature and
acid-base status in tissues, cells, and subcellular system
P60HL-151 57-07 0012 Comprehensive center for sickle
cell disease - Sickling and intracellular pH (human)
** POlHL-15194-07 0006 Pathophysiology of
cardiopulmonary dysfunction - Kinetics of gas exchange-
Velocity of Bohr effect in erythrocytes (human)
POlHL-16833-04 0003 Hemoglobin and red cell system in
hemoglobinopathies - Oxygen binding curves and equilibria
(human)
ROlHL-22258-01 New aspects of pharmacology related to
carbonic anhydrase
RESPIRATORY GAS LEVELS, CARBON DIOXIDE
TENSION
SEE ALSO RESPIRATORY GAS LEVELS, BOHR EFFECT
SEE ALSO RESPIRATORY GAS LEVELS, HYPERCAPNIA
SEE ALSO RESPIRATORY GAS LEVELS, HYPOCAPNIA
POlHL-06285-18 0128 Cardiovascular-respiratory
physiology and biochemistry - Pulmonary circulation in fetal
lambs in utero
POlHL-06285-18 0129 Cardiovascular-respiratory
physiology and biochemistry - Pulmonary microcirculation in
the fetus and neonate (lambs)
POlHL-06285-18 0147 Cardiovascular-respiratoiy
physiology and biochemistry - Metabolic regulation of
cerebral microcirculation (cats)
P01HLO6285-18 0180 Cardiovascular-respiratory
physiology and biochemistry - Vagal C-fibers and their
influence on visceral and somatic function (animals)
POlHL-06285-18 0181 Cardiovascular-respiratory
physiology and biochemistry - Regulation of respiration-
Role of vagus nerve (dogs)
RES
PCI HI '06285 18 0182 Cardlovaicular respiratory
physiology and blochemijlry Structure and (unction ot
vascular chemoreceptors (cats, rats)
POIHl 06285 18 0198 Cardiovascular respiratory
physiology and biochemistry Renal tubular secretion of
hydrogen ion (animals)
POIHL 07896 15 0030 Environmental biomedical research
program Narcosis caused by inert gases at raised
pressures (human, animals)
P01HL07896 15 0043 Environmental biomedical research
program Effect of hyperbaric oxygen on the lung (human,
rabbits)
POIHL 07896 15 0048 Environmental biomedical research
program Respiratory performance in divers at 1400 FSW
POIHL 07896 15 0055 Environmental biomedical research
program Cerebral blood flow by Xenon 133 inhalation
(human)
POlHL-08805 15 0044 Regulation of ventilation and
pulmonary circulation Neurochemical interactions in
respiratory control (human, dogs, goats)
■ POIHL 08899 14 0018 Tolerance to respiratory gases in
health and disease Effects of respiratory gases at
extreme pressures (human)
POlHL-08899-14 0023 Tolerance to respiratory gases in
health and disease Hypoxia and hyperoxia in respiratory
response in regards to PC02 (human)
POlHL-08899 14 0038 Tolerance to respiratory gases in
health and disease Brain vessels change in alveolar
arterial gas tensions (human, monkeys)
' POIHL 08899 14 0039 Tolerance to respiratory gases in
health and disease Dose response studies of oxygen on
C02 reactivity in brain vessels (human)
POIHL 08899-14 0055 Tolerance to respiratory gases in
health and disease Oxygen effects on organ functions-
Extension of tolerance
POlHL-10342-13 0011 The integrated function of
respiration and circulation Control of respiration 1-
Peripheral chemoreceptor studies (cats)
POlHL-10342-13 0026 The integrated function of
respiration and circulation - Control of respiration-
Characterization of the aortic body (cats)
POlHL-11678-11 0009 Cardiovascular dynamics and their
control - Control of respiration (cat. human)
* POlHL-12738-10 0124 Physiologic pharmacology and its
clinical applications Counterpulsation on myocardial
ischemia measured by carbon dioxide tension (dogs)
P50HL-14153-07 0017 Johns Hopkins Lung Center-
Chronic diseases of airways - Collateral ventilation and
pulmonary interdependence (pig. dog. human)
P50HL-14218-07 0013 Pulmonary SCOR-Newborn lung
center - Longitudinal study of RDS -Monitoring fetal P02
and PC02 during labor (human)
P50HL-14218-07 0018 Pulmonary SCOR-Newborn lung
center - W/hole body buffering in acute hypercapnia (dogs)
POlHL-14388-07 0185 Regulation of the circulation in
pathological states - Reflex control of venous tone (human,
rabbits, dogs)
'* POlHL-14414-07 0004 Environmental influences on
cardiorespiratory and cellular functions - Role of diffusion
in gas exchange (chicken egg)
P01HL14414-07 0014 Environmental influences on
cardiorespiratory and cellular functions • Temperature and
acid-base status in tissues, cells, and subcellular system
POlHL-14580-07 0003 Program project in respiratory
mechanics - Chest wall mechanics and respiratory control
(human, dogs)
** ROlHL-14870-06 Dynamics of oxygen and carbon dioxide
regulation (animals)
POlHL-14985-07 0002 Adaptation to hypoxia - Oxygen
transport in man at high altitude
POlHL-14985-07 0003 Adaptation to hypoxia - Hypoxia
and oxygen transport (human, dogs)
P50HL-15061-07 0013 Response of lung to injury -
Exchange transfusion in infants with respiratory distress
syndrome (human, sheep)
P01HL15194-07 0009 Pathophysiology of
cardiopulmonary dysfunction - Kinetics of gas exchange-
Diffusion and erythrocytes reaction rates (human, dogs)
** POlHL-15194-07 0018 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation,
metabolic demand and vasodilatory reserve (human, dogs)
POlHL-15194-07 0020 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation in
arteriographically normal arteries (human)
ROlHL-15655-05 Blood flow and gas exchange in placenta
and lungs (sheep) rabbits)
ROlHL-15810-06 Electrolyte physiology and respiratory
acid-base (dogs)
P60HL-15999-05 0021 Miami comprehensive sickle cell
center - Diphosphonates-Erythrocyte calcium loading,
maturation (human, chick embryo)
ROlHL-16463-05 Localization of airways obstruction and
responses
POlHL-16833-04 0009 Hemoglobin and red cell system in
hemoglobinopathies - Rheological studies of sickled cells
(human)
POlHL-16878-05 0001 Control of ventilation in health
and disease - Ability of asthmatics to detect added
resistive and elastic loads
ROlHL-17322-04 Functional characteristics of smooth
muscle isolated from lung (animals)
(contd)
•Excludes routine methodology OR covers only general projects which preclude i
••Oriented significanth' to above subject.
ndexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
RES
P50HL-1 7655-04 0014 Study of ischemic heart disease ■
Blood flow and gas tension in myocardial ischemia and
infarction (dog, monkey)
P50HL17670-04 0022 Study of ischemic heart disease -
Myocardial metabolism in hypoxia and recover (rabbit,
toad, dog)
POlHL-17731-04 0010 Physiological basis of pulmonary
disease - Gas exchange kinetics (dogs)
P50HL-19187-02 0001 Pediatric pulmonary SCOR-Hyaline
membrane disease ■ Hyaline membrane disease -Changes
in lung mechanics and gas exchange (monkeys)
ROlHL-19410-03 Dynamic interrelations underlying
exercise hyperpnea (human)
ROlHL-19414-03 Protection of myocardium during cardiac
surgery (dogs, cats, human)
POlHL-19737-02 0011 Cellular and molecular aspects of
respiratory physiology - Chemical and metabolic factors on
peripheral chemoreceptor activity (cats)
ROlHL-20122-02 Operational mechanisms of airway
receptors (dogs, pigs)
ROIHL 20399-03 Vascular control in experimental diabetes
mellitus (dog)
POlHL-21016-02 0007 Sickle cell anemia and other
hemoglobinopathies - Cellular determinants of red cell
sickling
ROlHL-21 158-02 Cardiac receptors with vagal Cfiber
afferents (cats)
ROlHL-21851-01 Cerebral microcirculation in experimental
hypertension (cats, rabbits)
R23HL-21901-01 Hypertension, microvascular control and
exercise (rats)
ROlHL-2262201 Sleep apnea and desaturation-
mechanisms and incidence (human)
" R23HL-22932-01 Effect of carbon dioxide on local gas
exchange (dogs)
R23HL-22975-01 Dynamics of autoregulation of muscle
blood flow (dogs)
ROlHL-23140-01 Determinants of irreversible ischemic
injury in heart (dog, rat)
ROlHL-23604-01 Hepatic microvascular regulatory
mechanisms (rat)
" ROlHL-23982-01 Control of coronary flow by carbon
dioxide tension (dogs)
RESPIRATORY GAS LEVELS, CYANOSIS
SEE ALSO HEMOPROTEINS, METHEMOGLOBINEMIA
POlHL-10436-13 0008 A multidisciplinary study of
congenital heart disease - Physiologic consequences of
chronic hypoxemia (human)
R01HL18328-03 Hemoglobin function and tissue
oxygenation (human, dogs)
POlHL-2101602 0015 Sickle cell anemia and other
hemoglobinopathies - EPR study of NO derivatives of Hb
Beth Israel (human)
RESPIRATORY GAS LEVELS, HYPERCAPNIA
ROlHL-02888-22 Interrelationships of circulation and
respiration (opossum, cats)
P01HL0628518 0125 Cardiovascular-respiratory
physiology and biochemistry - Myocardial function in the
fetal and neonatal lamb
POlHL-06285-18 0182 Cardiovascular-respiratory
physiology and biochemistry ■ Structure and function of
vascular chemoreceptors (cats, rats)
ROlHL-08789-11 Respiratory muscles and ventilatory
control in man (and dogs)
POlHL-0880515 0044 Regulation of ventilation and
pulmonary circulation - Neurochemical interactions in
respiratory control (human, dogs, goats)
" P01HL08899-14 0014 Tolerance to respiratory gases in
health and disease - Cellular and renal responses to
hypercapnia and hypocapnia (dogs)
ROlHL-09154-14 Central control of distribution of organ
blood flow (monkeys)
P01HL10342-13 0011 The integrated function of
respiration and circulation - Control of respiration 1-
Peripheral chemoreceptor studies (cats)
POlHL-10342-13 0026 The integrated function of
respiration and circulation ■ Control of respiration-
Characterization of the aortic body (cats)
ROlHL-1180210 Cardiovascular surgical research (dogs,
sheep, swine, cats, monkeys)
R01HL1256409 Control of respiration and blood gases
(human, dog)
ROlHL-12614-09 Microcirculatory control mechanisms and
hypertension (bats, rats)
R01HL1323308 Cardiorespiratory control in exercise
(human)
R01HL13885-08 9001 Cystic fibrosis and pulmonary
disease - Pulmonary function core facility (infants,
children)
ROlHL-13888-15 Regulation of respiration
'* P50HL1421807 0018 Pulmonary SCOR -Newborn lung
center • Whole body buffering in acute hypercapnia (dogs)
POlHL-14388-07 0155 Regulation of the circulation in
pathological states - Cardiopulmonary afferent activity,
carotid chemo-baroreceptor reflexes
POlHL-14985-07 0004 Adaptation to hypoxia
breathing in respiratory failure (human dogs)
POlHL-14985-07 0013 Adaptation to hypoxia
mountain sickness (men)
'* ROlHL-15810-06 Electrolyte physiology and respiratory
acid-base (dogs)
- Control of
Chronic
478
ROlHL-16022-05 Determinants of the ventilatory response
to hypoxia (goats, cats)
ROlHL-1606605 Studies on neurogenic control of the
circulation (human, dogs)
ROlHL-1731404 Effects of anesthesia and loading on
respiration (human, cats)
ROlHL-17711-05 Mechanism of hypoxic regulation of lung
circulation (rats, cats, guinea pigs)
POlHL-17813-04 0006 Lung disease and the oxygenation
of blood and tissue Assessment of respiratory muscle
contractile force (human, dogs)
ROlHL-17903-03 Regional circulatory responses to hypoxia
(rats, cats, rabbits)
ROlHL-18007-05 Neural mechanisms controling motor act
of breathing (cats, human)
ROlHL-18191-04 Models of hypoxic pulmonary
hypertension (cattle, minipigs)
ROlHL-18489-03 Hemodynamic interactions of vasoactive
chemicals (rats)
P50HL-19185-02 0007 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Sodium bicarbonate and
albumin in resuscitation of preterm infants (human)
P50HL-19187-02 0011 Pediatric pulmonary SCOR-Hyaline
membrane disease - Effects of hypoxia and hypercapnia on
developing nervous system (monkey human)
P50HL-19190-02 0006 Pulmonary SCOR-Pathophysiology,
management of IRDS - Asphyxia -Respiratory control (dogs)
P50HL-19190-02 0007 Pulmonary SCOR-Pathophysiology,
management of IRDS - Asphyxia -Cerebral metabolism (dog,
rat)
ROlHL-19248-03 Breathing pattern variation and
mechanical influences
Characterization of collateral blood
Respiration during prolonged hypercapnia
Brain stem integration of chemoreceptor
Cold induced pulmonary hypertension
Respiratory neurochemical control
ROlHL-19275-03
vessels (dogs)
** ROlHL-20568-03
(rats)
ROlHL-2057403
activity (cats)
ROlHL-20719-02
(cattle)
ROlHL-20847-02
(human, goats)
ROlHL-20864-01 Postnatal maturation of cardiovascular
regulatory system (minipig)
R23HL-20968-02 Respiratory failure-Control and muscle
dysfunction (human)
** ROlHL-22022-01 Respiratory muscle dysfunction in
respiratory failure (human)
ROlHL-22259-01 Modification of susceptibility to oxygen
poisoning (rats)
R01HL-22641-01 Ventilation, perfusion, and systemic
arterial reflexes (dogs)
ROlHL-22650-01 Regulatory mechanisms of erythropoietin
production (human, rats, mice)
ROlHL-22910-01 Control of breathing pattern in health
and disease (human, animals)
ROlHL-23601-01 Early hypoxia and development of
respiratory control
RESPIRATORY GAS LEVELS, HYPOCAPNIA
** ROlHL-00759-29 Regulation of electrolyte and acid base
equilibrium (dogs)
** POlHL-0889914 0014 Tolerance to respiratory gases in
health and disease - Cellular and renal responses to
hypercapnia and hypocapnia (dogs)
POlHL-08899-14 0039 Tolerance to respiratory gases in
health and disease - Dose-response studies of oxygen on
C02 reactivity in brain vessels (human)
POlHL-14388-07 0185 Regulation of the circulation in
pathological states - Reflex control of venous tone (human,
rabbits, dogs)
*• P01HL14985-07 0002 Adaptation to hypoxia - Oxygen
transport in man at high altitude
POlHL-14985-07 0003 Adaptation to hypoxia - Hypoxia
and oxygen transport (human, dogs)
ROlHL-15469-06
dogs, rats)
" R01HL15810-06
acid-base (dogs)
R01HL-1G463-05
responses
R01HL17873-04
asthma (human)
ROlHL-21318-02
Human ventilatory adaptation (also.
Electrolyte physiology and respiratory
Localization of airways obstruction and
Pathophysiology of exercise-induced
Mechanisms of emotions' asthma
triggering effect (human)
RESPIRATORY GAS LEVELS, HYPOXIA
SEE ALSO CEREBROVASCUUR DISORDERS BRAIN ISCHEMIA
AND HYPOXIA
SEE ALSO HEART DISORDERS, CORONARY, MYOCARDIAL
ISCHEMIA AND HYPOXIA
SEE ALSO HEMOPROTEINS, METHEMOGLOBINEMIA
SEE ALSO KIONEY-CIRCUUTORY DISORDERS, RENAL
ISCHEMIA AND HYPOXIA
SEE ALSO RESPIRATORY ASSIST AND OXYGEN
ADMINISTRATION
SEE ALSO RESPIRATORY CIRCULATORY DISORDERS
PULMONARY ISCHEMIA AND HYPOXIA
SEE ALSO RESPIRATORY GAS LEVELS, CYANOSIS
R01HL02228-24 Respiration, circulation, and heat
regulation in exercise (bird, mammals)
ROlHL-02888-22 Interrelationships of circulation and
respiration (opossum, cats)
RES
ROlHL-05883-18 0002 Reflex control of resistance and
capacitance vessels Adenosine, adenine nucleotides and
vascular smooth muscle (dog)
ROlHL-05883-18 0007 Reflex control of resistance and
capacitance vessels - Prostaglandins and skeletal muscle
blood flow (dogs)
POlHL-06285-18 0182 Cardiovascular-respiratory
physiology and biochemistry - Structure and function of
vascular chemoreceptors (cats, rats)
POlHL-06296-18 0005 Cardiovascular and pulmonary
adaptation to stress - Regulation of ventricular
performance (animals)
POlHL-06664-17 0036 Cardiopulmonary function in
remediable vascular disease - In vitro studies on the
mechanism of ischemic damage to cells (rabbits)
POlHL-06664-17 0043 Cardiopulmonary function in
remediable vascular disease - Alveolar hypoxic
vasoconstriction -Control and clinical significance (dog,
human)
Regulation of ventilation and
Adaptation of lungfish-Estivation
Regulation of ventilation and
Pulmonary edema (rabbits)
Regulation of ventilation and
Carotid body (cats)
Tolerance to respiratory gases in
Acid-base related influences of
POlHL-08805-15 0006
pulmonary circulation
POlHL-08805-15 0025
pulmonary circulation
POlHL-08805-15 0039
pulmonary circulation
POlHL-08899-14 0033
health and disease
hypoxia (human)
ROlHL-09154-14 Central control of distribution of organ
blood flow (monkeys)
POlHL-10342-13 The integrated function of respiration
and circulation
POlHL-10342-13 0011 The integrated function of
respiration and circulation - Control of respiration 1-
Peripheral chemoreceptor studies (cats)
P01HL10342-13 0019 The integrated function of
respiration and circulation - Cerebral circulation and
metabolism (dogs)
POlHL-1034213 0026 The integrated function of
respiration and circulation - Control of respiration-
Characterization of the aortic body (cats)
POlHL-10342-13 0027 The integrated function of
respiration and circulation - Control of respiration-
Cardiovascular adjustment to hypoxia and carbon monoxide
POlHL-10436-13 0005 A multidisciplinary study of
congenital heart disease - Pulmonary physiology in
congenital heart disease (human)
POlHL-11678-11 0009 Cardiovascular dynamics and their
control - Control of respiration (cat, human)
ROlHL-12174-11 Ventilation/perfusion distribution in the
lung (human, mammals)
ROlHL-12564-09 Control of respiration and blood gases
(human, dog)
ROlHl-12614-09 Microcirculatory control mechanisms and
hypertension (bats, rats)
Local control of the microcirculation
Metabolic regulation of sugar transport
Mechanism of chemoreceptor discharge
Cardiorespiratory control in exercise
ROlHL-12792-09
(hamsters, rats)
ROlHL-13029-09
(pigeons, rats)
R01HL13134-07
(cats)
R01HL13233-08
(human)
ROlHL-13636-08 Effects of pharmacologic agents on heart
metabolism (human, rodents)
ROlHL-13841-16 Respiration during altitude
acclimatization (goats, dogs, rats, rabbits)
ROlHL-13885-08 9001 Cystic fibrosis and pulmonary
disease - Pulmonary function core facility (infants.
children)
ROlHL-13888-15 Regulation of respiration
P50HL-14138-05 0015 Center for research on
atherosclerosis - Arterial wall -Intermediary metabolism.
enzyme activity and bioenergetics
POlHL-14388-07 0185 Regulation of the circulation In
pathological states - Reflex control of venous tone (human.
rabbits, dogs)
POlHL-14414-07 0015 Environmental influences on
cardiorespiratory and cellular functions - Control of the
cardiovascular system (dogs)
ROlHL-14693-07 Survival value of physiological responses
to hypoxia (dogs)
P60HL-15160-07 0011 Center for sickle cell disease -
Study of human sickle cells in an animal model (rats)
ROlHL-15430-05 Cardiopulmonary adaptation of newborns
to altitude (human)
ROlHL-15469-06
dogs, rats)
ROlHL-15498-06
(rats)
ROIHL- 156 14-04
Human ventilatory adaptation (also.
Effects of physical training on heart
•Excludes routine melhodology OR covers only general projects which preclude indexing
Oriented significantly to above subject
at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant numhpt
Heredity and oxygen-Effects on health of
heart-lungs (South America)
ROlHL-15810-06 Electrolyte physiology and respiratory
acid-base (dogs)
POlHL-15832-06 0001 Chemical-structural predispositions
to lung injury - Chemical composition of lung connective
tissue proteins (human, animals)
P60HL-15999-05 0021 Miami comprehensive sickle cell
center - Diphosphonates -Erythrocyte calcium loading.
maturaiion (human, chick embryo)
(contd)
RES
P60HL 1600806 0014 Wayne St«l« University
comprehensive sickle cell center 7inc and red blood cell
metabolism in sicKle cell anemia (rats, human)
ROIHL 16066 01) Studies on neurogenic control ot the
circulation (human, dogs)
ROIHL 1682804 Gradient and transport ot oxygen in
tissue and oigans (mammals)
ROIHL 17403 03 Metabolic control ol cardiac output
(dogs)
ROIHL 174S204 0epolaii;3tion induced cardiac
automaticity (human, animals)
ROIHL 1751/03 Arterial wall oxygen transport in
atherosclerosis (rabbits, dogs)
PSOHL 17682 04 00C7 Study o( ischemic heart disease
Mechanisms of hypoxemia in myocardial infarction (human)
POIHL 1781304 0007 Lung disease and the oxygenation
ot blood and tissue Studies on the function of myoglobin
(dogs)
ROIHL 17826 04 Oxygen delivery to tissue (rat, dog)
ROIHL 1790303 Regional circulatory responses to hypoxia
(rats. cats, rabbits)
ROIHL 1808003 Extrinsic control of intestinal
microcirculation (dogs)
ROlHL-18206 04 Regulation of metabolism in oxygen
deficient hearts (rats)
R01H11859902 Cardiovascular pharmacology of
lonophores (dogs)
ROlHL-1860101 Regulation of neurotransmitter release by
adenosine (rats)
ROIHL 1896902 Arterial wall oxygenation (rabbits, dogs)
R01HL19000-03 Irreversible myocardial injury (rats)
R01HL1908201 Hypoxiainduced relaxation of vascular
smooth muscle
R01HL1924803 Breathing pattern variation and
mechanical influences
ROlHL-19270-03 Effects of erythropoiesis on platelets and
hemostasis (rats)
R01HL1927503 Characterization of collateral blood
vessels (dogs)
ROIHL 1929803 Pulmonary hemodynamics (dogs, cats)
' R01HL19673-03 Surgical aspects of shock and hypoxia
(dogs, monkeys, rats)
P01HL1971702 0004 Response of the lung to injury •
Regulatory and physical-chemical properties of lung lysyl
oxidase (animals)
P01HL1971702 0028 Response of the lung to injury -
Compensatory growth of the lung following pneumonectomy
(rabbits)
P01HL19737-02 0009 Cellular and molecular aspects of
respiratory physiology ■ Regulation of tissue oxygen tension
and body carbon monoxide stores (human, dogs)
P01HL1973702 0013 Cellular and molecular aspects of
respiratory physiology ■ Cell metabolism analytical facility
ROlHL-20153-02 Intracellular pH and myocardial
electropharmacology (dogs, guinea pigs)
ROlHL-20429-03 Study of effects of diabetes reactivity
(miniature pigs, rats)
POlHL-20552-02 0003 The development and regression of
cardiac hypertrophy - Muscle mechanics of the
hypertrophied left ventricle (rats)
ROlHL-20568-03 Respiration during prolonged hypercapnia
(rats)
ROlHL-20574-03 Brain stem integration of chemoreceptor
activity (cats)
ROlHL-20920-01 Control of hemoglobin synthesis (baboon)
ROlHL-20989-01 Pathophysiology of bronchial asthma
(sheep, dogs)
ROlHL-2103202 Injury, wall thickness, and arterial wall
oxygenation (dogs, rabbits)
ROlHL-21117-01 Altitude adaptation in chronic lung
disease (human)
ROlHL-21126-02 Exercise-induced bronchospasm in
children
ROlHL-21172-02 Regional oxygen consumption of heart
and other organs (animals)
R01HL-2U79-01 Volume regulation -Role of the membrane
potential (amphiuma)
R23HL-21559-01 Oxygen supply and blood flow through
aortic vasa vasorum (dogs)
ROlHL-22231-02 Modulation of calcium control of cardiac
myofibrils (rats)
** R23HL-22383-01 Biosynthesis -Response to oxygen
depletion (human, primates, rats)
ROlHL-22546-02 Baroreceptor reflex mechanisms in man
ROlHL-22623-01 Polyamines cellular mediators of
atherogenesis (human)
ROlHL-22650-01 Regulatory mechanisms of erythropoietin
production (human, rats, mice)
ROlHL-22715-01 Neural integration of the cardiovascular
reflexes (dogs))
ROlHL-22910-01 Control of breathing pattern in health
and disease (human, animals)
ROlHL-22928-01 Systematic study of bronchial circulation
(sheep)
R23HL-2297201 Microcirculatory function in hypotension
(rats, hamsters)
ROlHL-23128-01 Cardiac contractility-Ischemia and
hypoxia (rabbits, rats)
ROlHL-23211-01 Active normoxic pulmonary vasodilatation
(rat, dog, sheep)
ROlHL-23232-01 Effect of hypoxia on PVSM and Its
precursor cells
47»
*• ROIHL 23601 01 I arly hypoxia and development of
respiratory control
RESPIRATORY GAS LEVELS, HYPOXIA,
RESPIRATORY
SEE ALSO CONGENITAL ABNORMALITIES, RESPIRATORY
DISTRESS SYNOROME
SEE ALSO ENVIRONMENI, STRESS. ALTITUDE
SEE ALSO INIURItS, ACCIDLNIS, SUffOCATION
SEE ALSO RESPIRAIORY DISORDERS. RLSPIRATORY
INSUfflCIENCY (GENERAL)
SEE ALSO RESPIRATORY EUNCTION, HYPGVENTIUTION
(GENERAL)
SEE ALSO RESPIRATORY FUNCTION. HYPOVENTILATION.
RESPIRATORY CENTER DYSFUNCTION
SEE ALSO RESPIRATORY GAS LEVELS, HYPOXIA NEONATORUM
SEE ALSO TOXICOLOGY, GAS POISONING, CARBON MONOXIDE
ROIHL 04651 19 Remote stimulation by radio frequency
transmission (dogs, human)
** P01HL06664 17 0043 Cardiopulmonary function in
remediable vascular disease Alveolar hypoxic
vasoconstriction -Control and clinical significance (dog.
human)
** POIHL 08899-14 0008 Tolerance to respiratory gases in
health and disease Hypoxia in regards to respiratory and
brain circulatory control (goats)
** P01HL0889914 0023 Tolerance to respiratory gases in
health and disease • Hypoxia and hyperoxia in respiratory
response in regards to PC02 (human)
** POlHL-08899-14 0030 Tolerance to respiratory gases in
health and disease - Dynamic characteristics of respiratory
control components (human, cats)
POlHL-10342-13 0023 The integrated function of
respiration and circulation ■ Carbon dioxide transport and
CSF acid base balance (hogs, pigs)
** POlHL-1034213 0024 The integrated function of
respiration and circulation ■ Cytochrome P450 and
physiological response to hypoxia (rats)
P01HL1043613 0008 A multidisciplinary study of
congenital heart disease - Physiologic consequences of
chronic hypoxemia (human)
ROlHL-1253010 Emphysema -Respiratory function in
disease (human, dogs, rats)
ROlHL-1410207 Human physiology at 5360 meters-
Mountain environment
P50HL 14187-07 0015 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses -
Pathophysiologic responses of pulmonary capillary bed
(dog, human)
POlHL-14414-07 0003 Environmental influences on
cardiorespiratory and cellular functions - Exposure to
abnormal gaseous environments (human, dogs, rabbits)
POlHL-14985-07 0009 Adaptation to hypoxia - Influence
of chemosensitivity on control of breathing during sleep
(human, dogs)
P60HL15160-07 0015 Center for sickle cell disease ■
Lung function abnormalities in sickle cell
hemoglobinopathies (human)
POlHL-15832-06 0007 Chemical-structural predispositions
to lung injury - Inactivation of vasoactive agents by the
lung (human, rats. cats, dogs)
POlHL-15832-06 0012 Chemical-structural predispositions
to lung injury - Contractile structures and contractility in
cells of lung respiratory tract
R01HL16022-05 Determinants of the ventilatory response
to hypoxia (goats, cats)
ROlHL-16784-03 Lung tissue and water volume (human,
dogs)
** POlHL-1683304 0016 Hemoglobin and red cell system in
hemoglobinopathies - Calciumindiced membrane damage
in Hb SS disease (human, animals)
ROlHL-17314-04 Effects of anesthesia and loading on
respiration (human, cats)
R01HL17322-04 Functional characteristics of smooth
muscle isolated from lung (animals)
** ROlHL-17711-05 Mechanism of hypoxic regulation of lung
circulation (rats, cats, guinea pigs)
POlHL-17813-04 0001 Lung disease and the oxygenation
of blood and tissue ■ Diffuse interstitial lung disease-
Pathophysiology (human, dogs)
ROlHL-1807004 Regulation of intrapulmonary airways
and vessels (human, animals)
** ROlHL-18145-03 Oxygen transport mechanisms in hypoxia
(dogs, rats, rabbits)
ROlHL-18191-04 Models of hypoxic pulmonary
hypertension (cattle, minipigs)
ROlHL-18630-03 Pulmonary hemodynamics in atelectasis
and hypoxia (dogs)
•* P50HL-19187-02 0011 Pediatric pulmonary SCOR-Hyaline
membrane disease - Effects of hypoxia and hypercapnia on
developing nervous system (monkey, human)
ROlHL-19225-02 0001 Types and mechanims of
pulmonary hypertension ■ Structural changes (human,
animals)
ROlHL-19225-02 0004 Types and mechanims of
pulmonary hypertension ■ Structural changes in human
pulmonary circulation (human, animals)
** R01HL19449-03 Gas exchange in acute respiratory failure
P01HL19717-02 0025 Response of the lung to injury ■
Role of oxygen in regulation of lung growth and
development (rats)
** ROlHL-19779-03 Biochemical basis of oxygen damage to
lung cells (guinea pigs, rats)
RES
ROIHl 20122 02 Operational mechanumi ol airway
receptors (dogs, pigs)
ROIHI 20366 03 Protein turnover and ammo acid
transport by lung (rats)
ROIHL 203/1 02 Intravascular redistribution ot blood
volume (dogs)
ROIHL 20/1902 Cold induced pulmonary hypertension
(cattle)
ROIHL 2084/ 02 Respiratory neurochemical control
(human, goats)
R23HL 20968 0? Respiratory failure Control and muscle
dysfunction (human)
•• ROIHL 21159 02 Pathophysiological effects of hypoxia
(rats)
•• R23HL 2116801 Hypoxemic respiratory failure Physiologic
evaluation (human, dogs)
R01HL713/602 Blood gas barrier solute and water
transport (rabbits)
POIHL 2158402 0003 Respiratory mechanics m normal
and abnormal states Effects of anesthesia on ventilation
and respiratory mechanics in man
ROIHL 22296-01 Autonomic mechanisms in man
** R23HL 22621 01 Blood cell-mediated pulmonary (human)
R01HL-23209-01 Autonomic receptors of the pulmonary
vasculature (mammals)
ROIHL 23210-01 Biology of normal and hypertrophied
pulmonary vessels (cat. human)
** ROlHL-23224 01 Hypoxia and pulmonary vascular smooth
muscle (rat. cat)
" NOlHR-62942-04 Nocturnal oxygen therapy in chronic
hypoxic lung disease (humam)
" NOIHR 62943-05 Nocturnal oxygen therapy in chronic
hypoxic lung disease (human)
** NOlHR-6294404 Nocturnal oxygen therapy in chronic
hypoxic lung disease (human)
** NOlHR-62945-04 Nocturnal oxygen therapy in chronic
hypoxic lung disease (human)
** NOlHR-62946-04 Nocturnal oxygen therapy in chronic
hypoxic lung disease (human)
** NOlHR-62947-04 Nocturnal oxygen therapy in chronic
hypoxic lung disease (human)
RESPIRATORY GAS LEVELS, HYPOXIA FETAL
ROlHL-01755-25 Fetal and neonatal cardiovascular
function (sheep)
R01HL03357-21 Humoral control of blood cell formation
and release (rats, mice)
POlHL-06285-18 0132 Cardiovascular-respiratory
physiology and biochemistry - Umbilical-placental
circulatory responses (lambs)
POlHL-06285-18 0133 Cardiovascular-respiratory
physiology and biochemistry • Decreased uterine blood flow
and fetal development (lambs)
P01HL06285-18 0136 Cardiovascular-respiratory
physiology and biochemistry ■ Fetal microcirculation in
utero (rabbits, lambs)
POlHL-06296-18 0005 Cardiovascular and pulmonary
adaptation to stress - Regulation of ventricular
performance (animals)
POlHL-10436-13 0015 A multidisciplinary study of
congenital heart disease • Fetal and neonatal
cardiovascular physiology (sheep)
ROIHL 10834-09 Fetal and neonatal pulmonary circulation
(goats)
R01HL13634-08 Renal hypertension in pregnancy (sheep)
P50HL-14214-07 0029 Newborn lung center for hyaline
membrane disease - The diving reflex -Perinatal asphyxia,
pulmonary ischemia and HMD (sheep)
P50HL-14218-07 0006 Pulmonary SCOR-Newborn lung
center ■ Biochemical characteristics of the lung in RDS
(human, sheep)
P50HL-14218-07 0014 Pulmonary SCOR-Newborn lung
center - Longitudinal study of RDS -Monitoring fetal
breathing movements (human)
ROlHL-1565505 Blood flow and gas exchange in placenta
and lungs (sheep) rabbits)
P50HL-17682-04 0010 Study of ischemic heart disease ■
Core clinical enzyme laboratory (human, mice, dogs, rats)
P50HL-17682-04 0018 Study of ischemic heart disease •
Biochemistry of ischemia -Heart cell and organ culture
(mice, rats, cattle)
P50HL 17682-04 0023 Study of ischemic heart disease -
Core cell and organ culture laboratory (mice)
ROlHL-19010-03 Metabolism and cell biology of lung
surfactant system (rabbits, sheep)
P50HL-1918502 0003 Pulmonary SCOR-Neonatal
respiratory distress syndromes ■ Factors affecting formation
and release of pulmonary surfactant in fetal lambs
P50HL-19185-02 0006 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Evaluation of risk factors
in neonatal respiratory distress (human, sheep)
P50HL-1918502 0007 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Sodium bicarbonate and
albumin in resuscitation of preterm infants (human)
** P50HL-19190-02 0007 Pulmonary SCOR -Pathophysiology,
management of IRDS - Asphyxia-Cerebral metabolism (dog,
rat)
P01HL19737-02 0006 Cellular and molecular aspects of
respiratory physiology - Tissue oxygenation and
mitochondrial respiratory activity (sheep)
ROlHL-19779-03 Biochemical basis of oxygen damage to
lung cells (guinea pigs, rats)
(contd)
Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
'Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number
RES
ROIHL-23601-01 Early hypoxia and development of
respiratory control
RESPIRATORY GAS LEVELS, HYPOXIA
NEONATORUM
SEE ALSO CONGENITAL ABNORMALITIES. RESPIRATORY
DISTRESS SYNDROME
ROlHL-0865914 Myocardial performance and metabolism
in the newborn (sheep)
POlHL-1043613 0015 A multidisciplinaiy study of
congenital heart disease ■ Fetal and neonatal
cardiovascular physiology (sheep)
R01HL-10834-09 Fetal and neonatal pulmonary circulation
(goats)
P50HL-14214-07 0032 Newborn lung center for hyaline
membrane disease - Evoked electroencephalographic
potential in infants with HMD (human)
R01HL-16022-05 Determinants of the ventilatory response
to hypoxia (goats, cats)
*• P50HL-19185-02 0006 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Evaluation of risk factors
in neonatal respiratory distress (human, sheep)
P50HL-19185-02 0007 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Sodium bicarbonate and
albumin in resuscitation of preterm infants (human)
M P50HL-19190-02 Pulmonary SCOR-Pathophysiology.
management of IRDS
** P50HLI919002 0006 Pulmonary SCOR-Pathophysiology.
management of IRDS - Asphyxia-Respiratory control (dogs)
** P50HL-19190-02 0007 Pulmonary SCOR-Pathophysiology,
management of IRDS - Asphyxia-Cerebral metabolism (dog,
rat)
" ROlHL-19352-03 Respiratory heat and water loss in
neonates
ROlHL-19752-03 Phospholipid synthesis by fetal lung In
organ culture (rats)
ROlHL-21176-02 Phospholipid exchange proteins in lung
tissue (lambs)
ROlHL-22636-01 Newborn lung function during
mechanical ventilation (human)
RESPIRATORY GAS LEVELS, OXYGEN TENSION
SEE ALSO RESPIRATORY ASSIST AND OXYGEN
ADMINISTRATION. HYPERBARIC OXYGENATION
SEE ALSO RESPIRATORY ASSIST AND OXYGEN
ADMINISTRATION, HYPEROXIA
SEE ALSO RESPIRATORY GAS ANALYZERS, OXIMETRY*
SEE ALSO RESPIRATORY GAS LEVELS, BOHR EFFECT
SEE ALSO RESPIRATORY GAS LEVELS, CYANOSIS
SEE ALSO RESPIRATORY GAS LEVELS. HYPOXIA
R01HL04612-20 Feedback between red cell production
and oxygen transport (rabbits, rats)
P01HL06285-18 0128 Cardiovascular-respiratory
physiology and biochemistry - Pulmonary circulation in fetal
lambs in utero
P01HL06285-18 0129 Cardiovascular-respiratory
physiology and biochemistry ■ Pulmonary microcirculation in
the fetus and neonate (lambs)
P01HL06285-I8 0130 Cardiovascular-respiratory
physiology and biochemistry - Ductus arteriosus-
Morphological development (human, lambs)
POlHL-06285-18 0145 Cardiovascular-respiratory
physiology and biochemistry - Pulmonary, pleural and
systemic microcirculation (animals)
** POIHL-06285-18 0178 Cardiovascular-respiratory
physiology and biochemistry - Biochemical regulation of
hypertrophy (rats, rabbits)
" POlHL-06285-18 0179 Cardiovascular-respiratory
physiology and biochemistry • Regulation of myocardial cell
growth (rats, chick embryo)
POlHL-06285-18 0182 Cardiovascular-respiratory
physiology and biochemistry - Structure and function of
vascular chemoreceptors (cats, rats)
POlHL-06296-18 0002 Cardiovascular and pulmonary
adaptation to stress - Respiratory muscle blood flow,
mechanics and metabolism (human, dog)
POlHL-06664-17 0010 Cardiopulmonary function in
remediable vascular disease - Ischemia and acute renal
failure (rats)
POlHL-07896-15 0019 Environmental biomedical research
program - Hyperoxic myopia (human)
POlHL-07896-15 0030 Environmental biomedical research
program - Narcosis caused by inert gases at raised
pressures (human, animals)
POlHL-07896-15 0043 Environmental biomedical research
program - Effect of hyperbaric oxygen on the lung (human,
rabbits)
POlHL-07896-15 0062 Environmental biomedical research
program - Vectorcardiograms during diving (human, dogs)
P01HL-08899-I4 0033 Tolerance to respiratory gases in
health and disease - Acid-base related influences of
hypoxia (human)
* POlHL-08899-14 0038 Tolerance to respiratory gases in
health and disease - Brain vessels change in alveolar
arterial gas tensions (human, monkeys)
POlHL-08899-14 0055 Tolerance to respiratory gases in
health and disease ■ Oxygen effects on organ functions-
Extension of tolerance
POlHL-1 1678-11 0020 Cardiovascular dynamics and their
control - Circulatory and pulmonary fluid dynamics during
pulmonary edema
ROlHL-1 1876-11 Regional myocardial blood flow and
metabolism (dogs, swine)
480
ROlHL-11906-11 Comparative study of heart function
(cats, rats, hedgehogs, squirrels)
ROlHL-1279209 Local control of the microcirculation
(hamsters, rats)
ROlHL-13134-07 Mechanism of chemoreceptor discharge
(cats)
P50HL-141 53-07 0017 Johns Hopkins Lung Center-
Chronic diseases of airways Collateral ventilation and
pulmonary interdependence (pig. dog. human)
* P50HL-142 18-07 0013 Pulmonary SCOR -Newborn lung
center - Longitudinal study of RDS-Monitoring fetal P02
and PC02 during labor (human)
POlHL-14388-07 0220 Regulation of the circulation in
pathological states - Pharmacology of the coronary
circulation in man
* POlHL-14414-07 0004 Environmental influences on
cardiorespiratory and cellular functions - Role of diffusion
in gas exchange (chicken egg)
POlHL-144 14-07 0014 Environmental influences on
cardiorespiratory and cellular functions - Temperature and
acid-base status in tissues, cells, and subcellular system
ROlHL-14523-07 Generation and regulation of force in
smooth muscle (animals)
* ROlHL-14870-06 Dynamics of oxygen and carbon dioxide
regulation (animals)
POlHL-14985-07 0013 Adaptation to hypoxia - Chronic
mountain sickness (men)
P50HL-15061-07 0002 Response of lung to injury -
Oxidative metabolism, phospholipid synthesis, and response
to toxins (rats)
P5OHL-15061-07 0013 Response of lung to injury -
Exchange transfusion in infants with respiratory distress
syndrome (human, sheep)
P60HL-151 57-07 0011 Comprehensive center for sickle
cell disease - Development of specific anti-sickling
compound (human)
P60HL-15157-07 0012 Comprehensive center for sickle
cell disease - Sickling and intracellular pH (human)
P60HL-151 58-07 0016 Comprehensive sickle cell center -
Biochemical studies in sickle cell anemia (human)
P60HL-15160-07 0011 Center for sickle cell disease -
Study of human sickle cells in an animal model (rats)
P60HL-15160-07 0015 Center for sickle cell disease -
Lung function abnormalities in sickle cell
hemoglobinopathies (human)
P60HL-151 62-07 0019 Comprehensive sickle cell center -
RBC-Blood rheology in sickle cell anemia and related
disorders (human, animal)
P60HL-15169-05 0018 Support tor center for sickle cell
disease - Studies on sickle cell disease (human, rats,
dogs)
POlHL-15194-07 0009 Pathophysiology of
cardiopulmonary dysfunction - Kinetics of gas exchange-
Diffusion and erythrocytes reaction rates (human, dogs)
POlHL-15194-07 0020 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation in
arteriographically normal arteries (human)
ROlHL-15390-12 Regulation of blood flow in the
microcirculation
ROlHL-15655-05 Blood flow and gas exchange in placenta
and lungs (sheep) rabbits)
POlHL-15832-06 0012 Chemical-structural predispositions
to lung injury - Contractile structures and contractility in
cells of lung respiratory tract
P60HL-15996-06 0010 Cincinnati comprehensive sickle
cell center - Whole blood viscosity in sickle cell anemia
(human)
P60HL-15999-05 0021 Miami comprehensive sickle cell
center - Diphosphonates-Erythrocyte calcium loading,
maturation (human, chick embryo)
POlHL-16137-05 0008 Alveolar biology - Macromolecular
events in pulmonary cells in toxic environments (animals)
ROlHL-16643-02
blood (animals)
ROlHL-16760-05
Fluorocarbon emulsions as artificial
Dynamic control of coronary blood flow
(dogs)
ROlHL-16828-04 Gradient and transport of oxygen in
tissue and organs (mammals)
POlHL-16833-04 0008 Hemoglobin and red cell system in
hemoglobinopathies - Membrane associated phenomena in
SS disease
POlHL-16833-04 0009
hemoglobinopathies
(human)
POlHL-16833-04 0016
hemoglobinopathies
Hemoglobin and red cell system in
Rheological studies of sickled cells
Hemoglobin and red cell system in
Calcium-indiced membrane damage
in Hb SS disease (human, animals)
ROlHL-17091-05 Anesthetics and microvascular response
to hemorrhage (rats)
ROIHL-17322-04 Functional characteristics of smooth
muscle isolated from lung (animals)
POlHL-17421-05 0002 Regulation and exchange in the
microcirculation - Metabolic and myogenic blood flow
regulation in microcirculation (animals)
POlHL-17421-05 0004 Regulation and exchange in the
microcirculation - Localization of flow regulation in the
microcirculation (cats, human)
ROlHL-17517-03 Arterial wall oxygen transport in
atherosclerosis (rabbits, dogs)
P50HL-17655-04 0014 Study of ischemic heart disease -
Blood flow and gas tension in myocardial ischemia and
infarction (dog, monkey)
•Excludes routine methodology OR covers only general projects which preclude indexing
"Oriented significantly to above subject
at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix tor investigator's name and grant number.
RES
P50HL-17682-04 0007 Study of ischemic heart disease ■
Mechanisms of hypoxemia in myocardial infarction (human)
ROlHL-18082-03 Erythrocyte phosphates and vertebrate
gas transport (amphibians, reptiles)
POIHL- 18208-04 0005 Center for the study of blood cell
rheology - RBC deformability and capillary flow
interrelations (human, mice)
ROlHL-18292-04 Vasodilation and microvascular oxygen
delivery (dog, hamster)
ROlHL-18489-03 Hemodynamic interactions of vasoactive
chemicals (rats)
P01HL-18708-03 0007 Oxygen, energy and contractility in
cardiac tissue - Surfaces, energy requirements, and
contractile proteins of cardiac cell in vitro
ROlHL-18969-02 Arterial wall oxygenation (rabbits, dogs)
ROlHL-18984-01 P50 effect on exercise limit in stable
angina (human)
ROlHL-19082-01 Hypoxia-induced relaxation of vascular
smooth muscle
P50HL-19187-02 0001 Pediatric pulmonary SCOR -Hyaline
membrane disease - Hyaline membrane disease-Changes
in lung mechanics and gas exchange (monkeys)
*• P50HL-19187-02 0009 Pediatric pulmonary SCOR-Hyaline
membrane disease - Non-invasive measurement and
monitoring of arterial oxygen tension (dogs, sheep)
P50HL-19187-02 0010 Pediatric pulmonary SCOR-Hyaline
membrane disease - Treatment, outcome of HMO-
Continuous positive airway pressure (human, monkey)
ROlHL-19202-03 Adenosine, prostaglandins In relation to
coronary flow (guinea pigs)
ROIHL 19218 03 Local regulation of coronary flow by
prostaglandins (rabbits)
POlHL-19242-02 0003 Study of vascular smooth muscle ■
Vasoactive metabolites from vascular muscle and
parenchymal tissue (animal)
ROIHL 19270 03 Effects of erythropoiesis on platelets and
hemostasis (rats)
ROIHL- 194 14-03 Protection of myocardium during cardiac
surgery (dogs, cats, human)
ROlHL-19449-03 Gas exchange in acute respiratory failure
•* POlHL-19737-02 0007 Cellular and molecular aspects of
respiratory physiology - Average oxygen tension of tissue
using radioisotopes (dogs)
" POlHL-19737-02 0009 Cellular and molecular aspects of
respiratory physiology - Regulation of tissue oxygen tension
and body carbon monoxide stores (human, dogs)
POlHL-19737-02 0011 Cellular and molecular aspects of
respiratory physiology - Chemical and metabolic factors on
peripheral chemoreceptor activity (cats)
ROlHL-20177-02 Effects of erythrocyte deformability on
tissue perfusion (rats)
ROlHL-20354-02 Direct determination of oxygen tension in
the clinical environment (human, dogs)
ROlHL-20605-02 Microvascular responses during intestinal
absorption (rats)
P60HL-20985-01 0003 Northern California sickle cell
center ■ Kinetics of sickling and clinical manifestations in
sickling disorders (human)
ROlHL-21009-02 Effects of air pollutants on lung cells in
culture (rats)
** ROlHL-2103202 Injury, wall thickness, and arterial wall
oxygenation (dogs, rabbits)
ROlHL-21 140-01 Studies of pulmonay alveolar
macrophage function (rabbits)
ROlHL-2 11 58-02 Cardiac receptors with vagal C-fiber
afferents (cats)
R23HL-21234-02
(rabbits)
R23HL-21332-02
microcirculation (cats)
R23HL-21409-02
(sheep)
ROlHL-21657-01
hypoxia (dogs)
R23HL-21901-01
exercise (rats)
ROlHL-22008-01
contractility (rats)
ROlHL-22113-02 Micro/macrovasculature in healing of
foot lesions (human)
ROlHL-22259-01 Modification of susceptibility to oxygen
poisoning (rats)
ROlHL-22664-01 Regulation of myocardial cell growth
(rats, guinea pigs)
ROlHL-228 15-01 Regional myocardial function after
revascularization (dogs)
R23HL-22975-01 Dynamics of autoregulation of muscle
blood flow (dogs)
ROlHL-23140-01 Determinants of irreversible ischemic
injury in heart (dog, rat)
ROlHL-23211-01 Active normoxic pulmonary vasodilatation
(rat, dog, sheep)
ROIHL-23604-01 Hepatic microvascular regulatory
mechanisms (rat)
ROlHL-23982-01 Control of coronary flow by carbon
dioxide tension (dogs)
RESPIRATORY GAS TRANSPORT
SEE ALSO CHEMICAL TRANSFER. HYDROGEN TRANSPORT
POlHL-08805-15 0006 Regulation of ventilation and
pulmonary circulation - Adaptation of lungfish-Estivation
(contd)
The regulation of cardiac hypertrophy
Pulsatile regulation of flow in the
cats)
Perinatal control of the ductus arteriosus
Regional non-ischemic myocardial
Hypertension, microvascular control and
Left ventrivular calcium content and
RES
POIHI 0880b lb 004b Rejulstion o( ventilation and
pulmonary circulation Intajiated description ot
noufochemical respiratory control system
•• POIHL 08899 14 002b Tolerance to respiratory jases in
health and disease Ellects ol oxygen on cardiopulmonary
gas transport functions (dogs)
POIHI 08899 14 0028 Tolerance to respiratory gases in
health and disease Inert gas exchange, oxygen inlluences
organs and tissues (human, rabbits, dogs)
POIHL 08899 14 0073 Tolerance to respiratory gases in
health and disease Biophysical mechanisms involved in
isobaric gas counlerdiffusion syndrome
•* ROIHL 12174 11 Ventilation/perlusion distribution in the
lung (human, mammals)
ROIHL 1287909 0007 Pulmonary transport and
metabolism in vivo Effects of temperature changes on
pulmonary transport
U POIHL 14414 07 Environmental influences on
cardiorespiratory and cellular functions
** POIHL 14414 07 0003 Environmental influences on
cardiorespiratory and cellular functions Exposure to
abnormal gaseous environments (human, dogs, rabbits)
*• POIHL 14414 07 0004 Environmental influences on
cardiorespiratory and cellular functions • Role of diffusion
in gas exchange (chicken egg)
POIHL 1441407 0008 Environmental influences on
cardiorespiratory and cellular functions Energetics of
swimming (human)
ROIHL 1552006 Total blood replacement by fluorocarbons
and polyols (rats)
•* R01HL1565505 Blood flow and gas exchange in placenta
and lungs (sheep) rabbits)
ROlHL-15668-06 Extracorporeal respiratory gas exchange-
A new approach (dogs)
ROlHL-16582-05 Artificial lungs (dogs)
R01HL1691604 0001 The role of albumins in lung water
accumulation • Capillary permeability (dogs, human)
** ROlHL-17358-04 Ventilatory adjustments for optimal
oxygenation (dogs, rats)
M POlHL-17731-04 Physiological basis of pulmonary disease
ROlHL-19173-03 Analysis of blood trauma from
microporous oxygenators (human, dogs, rabbits)
** R01HL19449-03 Gas exchange in acute respiratory failure
M P01HL19737-02 Cellular and molecular aspects of
respiratory physiology
** POlHL-19737-02 0004 Cellular and molecular aspects of
respiratory physiology ■ Rapid reactions and erythrocyte
exchanges of blood during respiratory transport
R23HL-2199001 Accuracy ot the ventilatory response to
exercise (dogs)
** ROlHL-22327-01 Transport of arterial blood gases through
skin (swine)
** ROlHL-22552-02 Abnormal alveolar permeability and lung
disease (sheep)
RESPIRATORY GAS TRANSPORT, CARBON
DIOXIDE TRANSPORT
** P01HL-1034213 0014 The integrated function of
respiration and circulation • Oxygen and carbon monxide
transfer (human, dogs, sheep)
** P01HL1034213 0023 The integrated function of
respiration and circulation ■ Carbon dioxide transport and
CSF acid base balance (hogs, pigs)
POlHL-10342-13 0024 The integrated function of
respiration and circulation - Cytochrome P450 and
physiological response to hypoxia (rats)
** R01HL14967-06 Chemoreceptor function in dynamic
ventilatory control (human, dogs)
** POlHL-15194-07 0006 Pathophysiology of
cardiopulmonary dysfunction - Kinetics of gas exchange-
Velocity of Bohr effect in erythrocytes (human)
ROlHL-16390-05 Cardiopulmonary control coupling in
exercise (dogs)
" POlHL-1773104 0010 Physiological basis of pulmonary
disease • Gas exchange kinetics (dogs)
** R01HL19008-02 Carbon dioxide diffusion in lung and
muscle tissues (dogs)
RESPIRATORY GAS TRANSPORT, OXYGEN
TRANSPORT
ROlHL-02228-24 Respiration, circulation, and heat
regulation in exercise (bird, mammals)
ROlHL-02799-22 Abnormal hemoglobins (human)
** R01HL03290-22 Controls of cardiac and vascular smooth
muscles (cats, rats, dogs)
** ROlHL-04612-20 Feedback between red cell production
and oxygen transport (rabbits, rats)
R01HL-05556-19 Proteins, lipoproteins-Structure and
reactivity (chicken, human, diving mammals)
POlHL-06285-18 0145 Cardiovascular-respiratory
physiology and biochemistry ■ Pulmonary, pleural and
systemic microcirculation (animals)
** POlHL-06296-18 0002 Cardiovascular and pulmonary
adaptation to stress - Respiratory muscle blood flow,
mechanics and metabolism (human, dog)
ROlHL-06950-17 Red cell metabolism (human,
vertebrates)
** POlHL-07896-15 0033 Environmental biomedical research
program • Breathing mechanism in birds
ROlHL-08299-16 Molecular biology of hemerythrin and
hemocyanin (invertebrates)
481
POIHI 10342 13 0014 The integrated function of
respiration and circulation Oxygen and carbon moniido
transfer (human, dogs, sheep)
POIHI 11310 12 0061 Mechanisms of cardiovascular
disease Computer simulation of transposition ol great
arteries in infants
* ROIHL 11901 12 0017 Effects of metabolic surgery on
the hyperhpidemias Membrane permeability, blood
viscosity, oxygen uptake Rheology studies (rabbits)
ROIHI 11906 11 Comparative study of heart function
(cats, rats, hedgehogs, squirrels)
ROIHL 12174 11 Ventilation/perfusion distribution in the
lung (human, mammals)
* ROIHL 12395 10 X ray study of oxygen carrying cobalt
complexes
POIHL 12738 10 0069 Physiologic pharmacology and its
clinical applications Blood rheology in coronary heart
disease (dogs)
ROIHL 12792 09 Local control of the microcirculation
(hamsters, rats)
* ROIHL 1315709 Molecular oxygen carriers- Synthesis,
structure, bonding
■• ROIHL 13412 17 Synthetic oxygen carriers
ROIHL 13989-05 Role of water in respiratiory protein
structure
ROIHL 14127-16 Methemoglobinemia and antihypertensive
drugs (cats, mice, rats)
POIHL 14414 07 0015 Environmental influences on
cardiorespiratory and cellular functions Control of the
cardiovascular system (dogs)
ROIHL 14508 10 Structure and function of respiratory
hemoproteins
" POlHL-1498507 0002 Adaptation to hypoxia - Oxygen
transport in man at high altitude
** POlHL-14985-07 0003 Adaptation to hypoxia - Hypoxia
and oxygen transport (human, dogs)
P60HL-15168-07 0010 Comprehensive sickle cell disease
center - Sickle cell center project (children)
•* POlHL-15194-07 0023 Pathophysiology of
cardiopulmonary dysfunction Distribution of ventilation-
Diffusion and cardiogenic agitation (dogs)
ROlHL-15284-06 Hemoglobin and myoglobin kinetic
studies (human, animals)
R01HL-15460-06 Molecular adaptation -Hemoglobin
systems of fish (marine)
** ROlHL-15640-06 Thermodynamic studies on model oxygen
carriers
ROlHL-15980-06 Reactions of hemeproteins and oxygen
(cattle)
** P60HL-16008-06 0017 Wayne State University
comprehensive sickle cell center - Oxygen transport kinetics
of pre- and post-sickling cells (human)
ROlHL-16093-05 Functional properties of hemoglobin and
erythrocytes
ROlHL-1629205 0009 Surgery and nonobstructive
coronary insufficiency - Exercise and supply-demand
balance (human)
ROlHL-16421-08 Determinants of RBC deformability and
capillary flow (human, mice)
ROlHL-16582-05 Artificial lungs (dogs)
** R01HL16828-04 Gradient and transport of oxygen in
tissue and organs (mammals)
** POlHL-16833-04 0003 Hemoglobin and red cell system in
hemoglobinopathies - Oxygen binding curves and equilibria
(human)
ROlHL-16931-04 Red cell storage and transfusion
(human, animals)
** ROlHL-17246-03 Oxygen uptake at one minute of exercise
(human)
** P01HL-1742105 0002 Regulation and exchange in the
microcirculation - Metabolic and myogenic blood flow
regulation in microcirculation (animals)
** ROlHL-17517-03 Arterial wall oxygen transport in
atherosclerosis (rabbits, dogs)
ROIHL 17578-04 Exercise performance in children with
heart disease
ROlHL-17794-03 Chelating agents as blood substitutes
** ROlHL-1780803 Effect of altered oxygen affinity on
oxygen transport (human, rats)
POlHL-178 13-04 0007 Lung disease and the oxygenation
of blood and tissue - Studies on the function of myoglobin
(dogs)
** ROlHL-17826-04 Oxygen delivery to tissue (rat, dog)
** ROlHL-1782804 Kinetic studies of hemerythrin reactions
(marine worms)
** ROlHL-17967-04 Limiting factors in oxygen uptake in the
lung
** ROlHL-18080-03 Extrinsic control of intestinal
microcirculation (dogs)
** ROlHL-18082-03 Erythrocyte phosphates and vertebrate
gas transport (amphibians, reptiles)
ROlHL-18096-04 Vasoactive agents in splanchnic viscera
(primates, dogs)
** ROlHL-1814503 Oxygen transport mechanisms in hypoxia
(dogs, rats, rabbits)
POlHL-18208-04 0006 Center for the study of blood cell
rheology - Analysis of flow in arterioles and capillaries
(human)
** ROlHL-18226-04 Mechanism of oxygen supply to tissue
(human, animals)
ROlHL-18292-04 Vasodilation and microvascular oxygen
delivery (dog, hamster)
klS
•■ ROIHI 1830904 Oxygen transport Hemogiobini with
modified hemes (horse)
M POIHI 18/08 03 Oxygen, energy and conlrictillly in
cardiac tissue
POIHL 18/08 03 0010 Oxygen, energy and contractility In
cardiac tissue Tissue oxygen ulili/ation (rats, dogs)
** ROIHL 19065 02 Molecular oxygen in biological fluids
ROIHI 19182 03 Surgical aspects ol myocardial
hypertrophy (dogs)
P50HL 19190 02 0009 Pulmonary SCOR Pathophysiology,
management of IRDS Developing non invasive neonatal
pulmonary monitoring systems (rabbit, human)
ROIHL 1944903 Gas exchange in acute respiratory failure
ROIHL 19824 02 Mass transfer m the microcirculation
ROIHI 20253 02 Effects of exercise on the heart and its
blood supply (dogs)
*• R23HL 20576 01 Airway turbulence and pulmonary oxygen
exchange
*• ROIHL 2089503 0006 Cineangiographic studies of
cardiovascular system Cardiomyopathy Hemodynamic,
radiologic, morphologic abnormalities (dog. rabbit)
P60HL 20985 01 0003 Northern California sickle cell
center Kinetics of sickling and clinical manifestations in
sickling disorders (human)
** POIHL 21016 02 0014 Sickle cell anemia and other
hemoglobinopathies - Human hemoglobin mutants with
abnormal oxygen binding
POIHL 21016 02 0015 Sickle cell anemia and other
hemoglobinopathies EPR study of NO derivatives of Hb
Beth Israel (human)
** R23HL 2155901 Oxygen supply and blood flow through
aortic vasa vasorum (dogs)
** ROlHL-22 123-02 The role of the red cell in diabetic
atherosclerosis (human)
ROlHL-22327-01 Transport of arterial blood gases through
skin (swine)
** ROlHL-23 12001 Chelating agents as blood substitutes
RESPIRATORY GASES
** POlHL-07896 15 0032 Environmental biomedical research
program - Fluorometry study of brain exposed to hyperbaric
oxygen (dogs, cats)
*• POlHL-08899-14 0075 Tolerance to respiratory gases in
health and disease ■ Gas diffusion rates and bubble
formation across membranes (animals)
POlHL-14388 07 0185 Regulation of the circulation in
pathological states • Reflex control of venous tone (human,
rabbits, dogs)
ROlHL-16093-05 Functional properties of hemoglobin and
erythrocytes
ROlHL-16784-03 Lung tissue and water volume (human,
dogs)
** ROlHL-18630-03 Pulmonary hemodynamics in atelectasis
and hypoxia (dogs)
** ROIHL 21257-02 Breathing in sleep-Airway control and
blood gases (cats)
R23HL21990-01 Accuracy of the ventilatory response to
exercise (dogs)
RESPIRATORY GASES, CARBON DIOXIDE
ROlHL-02888-22 Interrelationships ot circulation and
respiration (opossum, cats)
ROlHL-05556-19 Proteins, lipoproteins-Structure and
reactivity (chicken, human, diving mammals)
POlHL-06285-18 0188 Cardiovascular-respiratory
physiology and biochemistry - Physiology and pharmacology
in regulation of airvvays-hyperirritability (animals)
** POlHL-06285-18 0198 Cardiovascular-respiratory
physiology and biochemistry ■ Renal tubular secretion of
hydrogen ion (animals)
POlHL-08899-14 0012 Tolerance to respiratory gases in
health and disease - High oxygen for normal brain
metabolism and circulation in man
** POlHL-08899 14 0013 Tolerance to respiratory gases in
health and disease - Oxygen and carbon dioxide effects
upon human brain metabolism
POlHL-08899-14 0019 Tolerance to respiratory gases in
health and disease - High oxygen pressure upon carotid
chemoreceptor (cats)
POlHL-08899-14 0024 Tolerance to respiratory gases in
health and disease - Effects of oxygen pressures on
physiological control systems (human, dogs)
ROIHL 12174-11 Ventilation/perfusion distribution in the
lung (human, mammals)
ROlHL-12564-09 Control of respiration and blood gases
(human, dog)
P01HL14414 07 0003 Environmental influences on
cardiorespiratory and cellular functions - Exposure to
abnormal gaseous environments (human, dogs, rabbits)
** POlHL-15194-07 0022 Pathophysiology of
cardiopulmonary dysfunction - Kinetics of gas exchange-
Pulmonary carbon dioxide exchange (dogs)
ROlHL-15655-05 Blood flow and gas exchange in placenta
and lungs (sheep) rabbits)
ROlHL-16927-05 Structure and function of normal and
abnormal hemoglobin (human)
ROlHL-17571-03 Study of membrane permeability by NMR
relaxation (human)
ROlHL-17873-04 Pathophysiology of exercise-induced
asthma (human)
ROlHL-1796304 Human erythrocyte carbonic anhydrase
ROlHL-18309-04 Oxygen transport-Hemoglobins with
modified hemes (horse)
(contd)
•Excludes routine methodology OR covers only general projects which preclude
"Oriented significantly to above subject.
indexing at the specific level.
M Grant has subproieds describing specific research aspectS-
See Appendix for Investigator's name and grant number.
RES
ROlHL-19248-03 Breathing pattern variation and
mechanical influences
R23HL19601-01 Cardiac response to chronic metabolic
acidosis (rats)
POlHL-19737-02 0004 Cellular and molecular aspects of
respiratory physiology ■ Rapid reactions and erythrocyte
exchanges of blood during respiratory transport
P01HL19737-02 0008 Cellular and molecular aspects of
respiratory physiology - Kinetics of movement of acid
metabolites from cell to capillary blood (dogs)
POlHL-21016-02 0006 Sickle cell anemia and other
hemoglobinopathies - Analysis of the oxygen dissociation
curve of Hb S-containing red cells
R23HL-21434-02 Intrinsic control of coronary blood flow by
chemicals (guinea pigs)
ROlHL-2186018 Factors influencing responses to
adrenergic drugs (guinea pigs. rats, cats)
RESPIRATORY GASES, OXYGEN
SEE ALSO GAS ELEMENTS. OZONE
SEE ALSO RADIOISOTOPES. OXYGEN
ROlHL-02888-22 Interrelationships of circulation and
respiration (opossum, cats)
POlHL-07896-15 0029 Environmental biomedical research
program • Oxygen-helium diving resulting in high pressure
nervous syndrome (human, animals)
P01HL08899-14 0006 Tolerance to respiratory gases in
health and disease • Effects of extreme pressures of inert
gases in macaque monkey
** POlHL-0889914 0013 Tolerance to respiratory gases in
health and disease - Oxygen and carbon dioxide effects
upon human brain metabolism
POlHL-08899-14 0019 Tolerance to respiratory gases in
health and disease - High oxygen pressure upon carotid
chemoreceplor (cats)
P01HL0889914 0024 Tolerance to respiratory gases in
health and disease - Effects of oxygen pressures on
physiological control systems (human, dogs)
** POlHL-08899-14 0028 Tolerance to respiratory gases in
health and disease ■ Inert gas exchange, oxygen influences-
organs and tissues (human, rabbits, dogs)
POlHL-0889914 0029 Tolerance to respiratory gases in
health and disease - Isobaric gas counter diffusion
phenomena (human, pigs)
POlHL-08899-14 0076 Tolerance to respiratory gases in
health and disease - Bubble formation during gas
counterdiffusion (hamsters)
ROlHL-12174-11 Ventilation/perfusion distribution in the
lung (human, mammals)
R01HL13157-09 t^olecular oxygen carriers-Synthesis.
structure, bonding
ROlHL-13399-16 Heme protein structure and function
(human, horse, plants, bacteria)
** ROIHL-13581-11 Reactions of oxygen with heme proteins
POlHL-14414-07 0003 Environmental influences on
cardiorespiratory and cellular functions - Exposure to
abnormal gaseous environments (human, dogs, rabbits)
RO I HL- 17844-04 Artificial blood substitutes -02binding
iron chelates (human, mammals)
R01HL1848903 Hemodynamic interactions of vasoactive
chemicals (rats)
ROlHL-18647-03 Ischemic myocardial injury in cultured
heart cells (rats)
P01HL1973702 0004 Cellular and molecular aspects of
respiratory physiology ■ Rapid reactions and erythrocyte
exchanges of blood during respiratory transport
R23HL-2 1434-02 Intrinsic control of coronary blood flow by
chemicals (guinea pigs)
ROlHL-22406-01 Isobaric vascular bubbles and
decompression sickness (goats, models)
RESPIRATORY GASES, OXYGENATION
SEE ALSO OXIDATION-REDUCTION. OXIDATION
SEE ALSO RESPIRATORY ASSIST AND OXYGEN
ADMINISTRATION. HYPERBARIC OXYGENATION
ROIHL 05791 18 Structure and function in hemoglobins
(human)
M POlHL-08899-14 Tolerance to respiratory gases in health
and disease
P01HL0889914 0025 Tolerance to respiratory gases in
health and disease • Effects of oxygen on cardiopulmonary
gas transport functions (dogs)
** POlHL-08899 14 0031 Tolerance to respiratory gases in
health and disease - Studies in exercise (human, dogs)
POlHL-08899-14 0039 Tolerance to respiratory gases in
health and disease - Dose-response studies of oxygen on
C02 reactivity in brain vessels (human)
R01HL-10383-I2 Physical-chemical studies of hemoglobins
and erythrocyte (human)
POlHL-10539-12 0067 Pathophysiology of circulation -
Mechanical, electrophysiological studies -Isolated heart
muscle (dog. rat)
ROlHL-12524-10 Reaction of hemoglobin with ligands and
antibodies (human, carp)
ROlHL-12526-09 Raman spectra of heme proteins and
related molecules
ROlHL-13164-07 Interaction of the alpha and beta chains
of human hemoglobin
R01HL13399-16 Heme protein structure and function
(human, horse, plants, bacteria)
** R01HL13531-06 Coboglobins -Cobalt substituted myo and
hemoglobins
ROlHL-13581-11 Reactions of oxygen with heme proteins
482
P60HL 15162-07 0020 Comprehensive sickle cell center -
Biophysical studies of normal and sickle red cells (human)
POlHL-15194-07 0006 Pathophysiology of
cardiopulmonary dysfunction - Kinetics of gas exchange-
Velocity of Bohr effect in erythrocytes (human)
ROIHL 15520-06 Total blood replacement by fluorocarbons
and polyols (rats)
ROlHL-15627-06 X-ray and chemical studies of
metalloporphyrins
ROlHL-15640-06 Thermodynamic studies on model oxygen
carriers
R01HL-156S5-05 Blood flow and gas exchange in placenta
and lungs (sheep) rabbits)
R01HL15980-06 Reactions of hemeproteins and oxygen
(cattle)
P60HL 16008-06 0017 Wayne State University
comprehensive sickle cell center ■ Oxygen transport kinetics
of pre- and post-sickling cells (human)
P60HL-1600806 0018 Wayne State University
comprehensive sickle cell center - Hemoglobin S and RBC
membranes -Pathogenesis of irreversibly sickled cells
ROIHL 16580-04 Mathematical models for studying sickle-
cell disease
ROIHL 1668604 Properties of cytochrome oxidase (cattle.
bacteria)
POlHL-16833-04 0011 Hemoglobin and red cell system in
hemoglobinopathies • Relationship between hemoglobin and
RBC membrane in sickling cells (human, rats)
** ROIHL 1686005 Mossbauer studies of respiratory
hemoproteins
ROlHL-1692705 Structure and function of normal and
abnormal hemoglobin (human)
ROlHL-17358-04 Ventilatory adjustments for optimal
oxygenation (dogs, rats)
ROlHL-17494-07 Mechanism of liqand binding to
hemoglobin (human)
** POlHL-17731-04 0010 Physiological basis of pulmonary
disease - Gas exchange kinetics (dogs)
M POIHL- 178 13-04 Lung disease and the oxygenation of
blood and tissue
POlHL-17813-04 0001 Lung disease and the oxygenation
of blood and tissue ■ Diffuse interstitial lung disease -
Pathophysiology (human, dogs)
** POlHL-17813-04 0007 Lung disease and the oxygenation
of blood and tissue - Studies on the function of myoglobin
(dogs)
ROlHL-18226-04 Mechanism of oxygen supply to tissue
(human, animals)
** ROlHL-18292-04 Vasodilation and microvascular oxygen
delivery (dog. hamster)
** R01HL1832803 Hemoglobin function and tissue
oxygenation (human, dogs)
R01HL18660-03 Neurotransmitter receptors in human
erythrocytes
ROlHL-188 19-07 Chemical studies on sickle cell
hemoglobin (human)
** ROlHL-1896902 Arterial wall oxygenation (rabbits, dogs)
ROlHL-18984-01 P50 effect on exercise limit in stable
angina (human)
P50HL1918702 0010 Pediatric pulmonary SCOR-Hyaline
membrane disease - Treatment, outcome of HMD-
Continuous positive airway pressure (human, monkey)
ROIHL-19488-03 Picosecond laser studies of heme-
proteins
** POlHL-19737-02 0006 Cellular and molecular aspects of
respiratory physiology - Tissue oxygenation and
mitochondrial respiratory activity (sheep)
P60HL-20985-01 0003 Northern California sickle cell
center ■ Kinetics of sickling and clinical manifestations in
sickling disorders (human)
POlHL-210 16-02 0004 Sickle cell anemia and other
hemoglobinopathies - Kinetics of sickling
POlHL-21016-02 0005 Sickle cell anemia and other
hemoglobinopathies - Ligand kinetics in normal and Hb S
containing erythrocytes (human)
POlHL-21016-02 0006 Sickle cell anemia and other
hemoglobinopathies • Analysis of the oxygen dissociation
curve of Hb S-containing red cells
R23HL-21405-01 Respiratory muscles in regulation of
infant breathing (human)
ROlHL-21483-01 Electronic, thermodynamic and kinetics
of hemoglobin
ROlHL-22325-01 Thermodynamics in respiratory protein
binding (human, trout)
** ROlHL-22622-01 Sleep apnea and desaturation-
mechanisms and incidence (human)
ROlHL-2278001 Factors modifying the reaction properties
of HgS (human)
** R23HL-2297201 Microcirculatory function in hypotension
(rats, hamsters)
RESPIRATORY HYPERSENSITIVITY
SEE HYPERSENSITIVITY. RESPIRATORY HYPERSENSITIVITY
RESPIRATORY HYPOXIA
SEE RESPIRATORY GAS LEVELS. HYPOXIA. RESPIRATORY
RESPIRATORY INFECTIONS
SEE ALSO BACTERIAL DISEASES, ACTINOMYCETALES
INFECTIONS. TUBERCULOSIS
SEE ALSO MYCOSES. ASPERGILLOSIS
SEE ALSO RESPIRATORY DISORDERS. URYNGOTRACHEITIS
SEE ALSO RESPIRATORY DISORDERS. PNEUMONIA
RES
SEE ALSO VIRUS DISEASES, MYXOVIRUS. INFLUENZA
SEE ALSO VIRUSES. RESPIRATORY (GENERAL)
POlHL-0637017 0013 Cardiopulmonary and renal
pathology research center - Morphologic analysis of
vascular prosthesis (human, dogs)
POlHL-08805-15 0049 Regulation of ventilation and
pulmonary circulation - Pulmonary hypertension produced
by Dirofilaria immitis in the dog
ROlHL-1359607 Clearance of plasma proteins from
alveoli
ROlHL'13824-06 Defense mechanisms in pathogenesis of
emphysema (human, dogs)
ROlHL-13885-08 0006 Cystic fibrosis and pulmonary
disease - Cell mediated immunity and Pseudomonas
infections in cystic fibrosis (human)
ROIHL- 13885-08 0007 Cystic fibrosis and pulmonary
disease Alveolar macrophage defense mechanism
(human, rabbits)
ROIHL 13885-08 0008 Cystic fibrosis and pulmonary
disease Pseudomonas specific activation of alveolar
macrophages (human, rabbits)
P50HL14136-07 0003 Pulmonary SCOR -Airways
obstructive diseases - Acute pediatric respiratory disease
and COLD
P50HL 1413607 0017
obstructive diseases
(human)
P50HL 14136-07 9006
obstructive diseases
P50HL-14212-07 0006
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
••Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects
See Appendix for investigator's name and grant number.
Pulmonary SCOR-Airviays
Pediatric airways obstructive disease
Pulmonary SCOR -Airways
Pediatric lung function core
Correlated studies of pulmonary
fibrosis - Alveolar macrophage physiology (human, rodents,
rabbits)
• P50HL-14212-07 0015 Correlated studies of pulmonary
fibrosis - Pulmonary defense mechanisms and fibrotic lung
disease (rodents, rabbits)
• P50HL14218-07 0005 Pulmonary SCOR-Newborn lung
center ■ Prevention of infection in infants with respiratory
distress (human)
P50HLI4218-07 0017 Pulmonary SCOR-Newborn lung
center - Transvascular fluid exchange, vasoactive mediators
in ROS (sheep, cat)
P50HL-15061-07 0006 Response of lung to injury ■
Complement synthesis by pulmonary macrophages (guinea
pigs, human)
' P50HL-1506107 0007 Response of lung to injury -
Human factors for phagocytosis in normal and diseased
lungs
■ P50HL15061-07 0010 Response of lung to injury - An
animal model system for the study of bronchiolitis and its
sequellae (dogs)
P50HL 15092-07 0002 Immune and fibrotic response to
occupational environments ■ Longitudinal study of
sandblasters silicosis (human)
• P60HL-15169-05 0015 Support for center for sickle cell
disease - Pathophysiology of acute pulmonary infiltrates In
sickle cell disease (human)
P60HL15996-06 0003 Cincinnati comprehensive sickle
cell center - Prophylactic penicillin in treatment of sickle
cell anemia (human)
R01HL16463-05
responses
ROlHL-18308-03
transport (dogs)
R01HL19018-03
alveolitis (human)
P50HL19156-02 0001 Pulmonary SCOR-Chronic diseases
of airways ■ Irritability of airways induced by epithelial
damage in healthy subjects (human)
P50HL 19157-02 Studies in cystic fibrosis and
bronchiolitis
P50HL-19157-02 0002 Studies in cystic fibrosis and
bronchiolitis - Clinical core
P5OHL-19157-02 0003 Studies in cystic fibrosis and
bronchiolitis - Nasal mucosal function in patients with
cystic fibrosis
P50HL-19157-02 0011 Studies In cystic fibrosis and
bronchiolitis ■ Pathogenesis of bronchiolitis (children)
P50HL-19171-02 Pulmonary SCOR -Lung injury by
childhood infections
P50HL-19171-02 0001 Pulmonary SCOR-Lung injury by
childhood infections ■ Longitudinal study -Respiratory
infections and lung growth in normal children
P50HL19I71-02 0003 Pulmonary SCOR-Lung injury by
childhood infections - Natural history, host defense defects-
Children with chronic pulmonary disease
P50HL-19171-02 0004 Pulmonary SCOR-Lung injury by
childhood infections - Long-term effects of respiratory
infections in early childhood
P50HL19171-02 0005 Pulmonary SCOR-Lung injury by
childhood infections - Chronic respiratory disease of
children in North Carolina
P50HL-19171-02 0006 Pulmonary SCOR-Lung injury by
childhood infections - Development of model systems
(bacteria, viruses, hamsters)
P50HL-19171-02 0007 Pulmonary SCOR-Lung injury by
childhood infections - Immunologic studies in models of
lower respiratory tract infection (rodents)
P50HL19I7102 0008 Pulmonary SCOR-Lung injury by
childhood infections - Host-parasite interaction-Electron
microscopy, radioautography. histochemistry
(contd)
Localization of airways obstruction and
Comprehensive studies of mucociliary
Etiologic factors in cryptogenic fibrosing
RES
• PbOHl 19171 02 0009 Pulmoniiy SCOR lunj (nluiy by
childhood inleclions Host par.site mter.clion Scanning
electron microscopyi lie«;e luctuie methods
• PbOHL 19171 02 0010 Pulmoneiy SCOR Lung iniury by
childhood inleclions Metabolic pathways ol normal and
iniured cospitatofy cells
■• P50HL 19171 02 0011 Pulmonary SCOR Lung imury by
childhood inleclions Clinical support core
■• PbOHL 19171 02 0012 Pulmonary SCOR Lung inlury by
childhood inleclions Laboratory support core
ROIHI 19741 03 Murine CRD A model ol chronic
pulmonary inllammation (mice, rats)
•• ROlHl-20002 03 Pulmonary complications of vital
infections (children)
•* ROIHL 20063 03 Pathogenesis of pulmonary mycoplasma
infections (guinea pigs, mice) , ... >
•* R01HL20963 01 Experimental lung abscess (rabbits)
ROIHL 21314 02 Respiratory tract secretion of ions, water
and mucus (human, dogs)
•* ROIHL 2182901 Etiology of obstructive aitvuay disease in
children (also monkeys)
R23HL 22895 01 Smoke inhalation Biochemical and
cellular responses (rabbits, bacteria)
•* P60HL23282 01 0004 Comprehensive hospital/community
sickle cell center Bacterial, viral and mycoplasmal
infections and sickle cell disease complications
NOIHR 3290009 Pilot study to standardize the
measurement of closing volume' (human)
NOIHR 32902-07 Pilot study to standardize the
measurement of closing volume (human)
NOlHR-3290311 Pilot study to standardize the
measurement of 'closing volume' (human)
RESPIRATORY INSUFFICIENCY (GENERAL)
SEE RESPIRATORY DISORDERS, RESPIRATORY INSUFFICIENCY
(GENERAL)
RESPIRATORY INSUFFICIENCY POST-TRAUMATIC
SEE RESPIRATORY DISORDERS, RESPIRATORY
INSUFFICIENCY, SHOCK LUNG
RESPIRATORY MUSCLES
SEE ALSO BODY CAVITIES, DIAPHRAGM
** POlHL-06296-18 0002 Cardiovascular and pulmonary
adaptation to stress - Respiratory muscle blood flovi,
mechanics and metabolism (human, dog)
*• ROlHL-08789-11 Respiratory muscles and ventilatory
control in man (and dogs)
P01HL08805-15 0045 Regulation of ventilation and
pulmonaiY circulation - Integrated description of
neurochemical respiratory control system
P50HL-14153-07 0013 Johns Hopkins Lung Center-
Chronic diseases of airways ■ Pulmonary mechanics and
mediators of allergic reactions (guinea pigs, human)
** POlHL-14414-07 0007 Environmental influences on
cardiorespiratory and cellular functions - Neural control of
respiration (human, cats)
" P01HL1458007 0003 Program project in respiratory
mechanics - Chest wall mechanics and respiratory control
(human, dogs) .. u i.t
POlHL-16878-05 0003 Control of ventilation in health
and disease ■ Brain stem respiratory neurons in response
mechanical/chemical loading (animal)
ROlHL-17689-06 Neurophysiologic studies of respiratory
control (cats)
•* ROlHL-17715-04 Respiratory muscle afferents in
respiratory control (cats)
" POlHL-17813-04 0006 Lung disease and the oxygenation
of blood and tissue • Assessment of respiratory muscle
contractile force (human, dogs)
ROlHL-18007-05 Neural mechanisms controling motor act
of breathing (cats, human)
R01HL191 15-02 Hormonal control of tracheobronchial
cyclic AMP (rats, guinea pigs)
P50HL-19170-02 0003 Harvard pulmonary SCOR-Chronic
diseases of the airways • Mechanisms of bronchial
reactivity to acute and chronic airway challenge (dog)
P50HL-19170-02 0006 Harvard pulmonary SCOR-Chronic
diseases of the airways - Mechanism of overdistension
(human, animal)
** P50HL-19170-02 0009 Harvard pulmonary SCOR-cnronic
diseases of the airarays - Ventilatory muscle training in
chronic obstructive pulmonary disease (human)
ROlHL-20847-02 Respiratory neurochemical control
(human, goats)
R23HL-20968-02 Respiratory failure -Control and muscle
dysfunction (human)
ROlHL-21257-02 Breathing in sleep -Airway control and
blood gases (cats)
** R23HL-2 1405-01 Respiratory muscles in regulation ot
infant breathing (human)
** ROlHL-2 1500-02 Performance of respiratory muscles under
stress (dogs)
POlHL-21584-02 0004 Respiratory mechanics in normal
and abnormal states - Effects of anesthesia on respiratory
mechanics (dogs)
** POlHL-21584-02 0005 Respiratory mechanics in normal
and abnormal states ■ Regulation and behavior of airway
smooth muscle (human, animals)
** ROlHL-22022-01 Respiratory muscle dysfunction in
respiratory failure (human)
R01HL-23586-06 Pharmacologic control of hypersensitivity
phenomena (human)
4*9
RESPIRATORY PROTEINS (GENERAL)
SU Also HlMOPROlllNS
SEE Also MflALlOPROKlNS „„„„tc.uc
SEE ALSO PORPIIYROPROTEINS, METALIOPORPHYROPROTEINS
ROIHI 16860 05 Mossbauei studies ol respiratory
hemoproteins
•• ROIHL 19481 03 High field NMR studies of respiratory
proteins (human, horse, fish, microbes)
RESPIRATORY PROTEINS, REDOXINS
SEE ALSO FLAVODOXIN
SEE ALSO METALLOPROTEINS, FERREDOXIN
ROIHL 1365208 Metal sites in metalloproteins
(mushroom)
RESPIRATORY PROTEINS, RESPIRATORY
ENZYMES
SEE ALSO FLAVOPROTEIN ENZYMES
SEE ALSO NAD LINKED ENZYMES
SEE ALSO NADP LINKED ENZYMES
SEE ALSO OXIDOREDUCTASES
SEE ALSO OXYGENASES
SEE ALSO PEROXIDASES
** ROIHL 12576 10 Bioenergetics apparatus in heart
mitochondria
P50HL 1421807 0017 Pulmonary SCOR-Newborn lung
center Transvascular fluid exchange, vasoactive mediators
in RDS (sheep, cat) , , ^
POIHL 16748 05 0004 Cellular and immunological basis
of pulmonary diseases Cellular and immunological
processes in pulmonary defense systems
ROIHL 1692002 Proteases in normal and immunologically
injured lung (guinea pigs, rabbits)
ROIHL 18304 03 FT-infrared spectroscopy of heart muscle
energetics (cattle)
** ROIHL 1939203 Spectroscopic studies of respiratory
metalloproteins
RESPIRATORY SYNCYTIAL VIRUSES
SEE VIRUSES, MYXOVIRUSES, RESPIRATORY SYNCYTIAL
VIRUSES
RESPIRATORY SYSTEM (GENERAL)
SEE ALSO NASAL. NOSE
ROlHL-02942-22 Biochemistry of cardiovascular connective
tissue (human, cattle, primates)
** P01HL07896-15 0036 Environmental biomedical research
program - Respiratory heat loss in deep diving (infants,
dogs) ^ . , .
POlHL-12373-10 0016 Cardiopulmonary physiology and
pathophysiology - Histologyhistochemistry-Gough laboratory
P5OHL1413607 0004 Pulmonary SCOR -Airways
obstructive diseases - Morphometric studies of developing
emphysema (human)
ROlHL-1906603 Synthesis and evaluation of
prostaglandin metabolites (guinea pigs)
ROlHL-19379-03 Characterization of small-granule cells in
the lung (mammals)
ROlHL-19722-03 Aerosol growth in the respiratory system
(models) , . .
" P01HL1973702 0002 Cellular and molecular aspects ot
respiratory physiology - Airway smooth muscle in health
and disease (human, animals)
** ROlHL-206 11-02 Airway smooth muscle and cyclic
nucleotides
RESPIRATORY SYSTEM, ALVEOLAR
MACROPHAGES
POlHL-06285-18 0209 Cardiovascular-respiratory
physiology and biochemistry - Metabolic studies of isolated
lung cells (human, animals)
P01HL06285-18 0210 Cardiovascular-respiratory
physiology and biochemistry - Physicochemical and
enzymatic studies of lung surfactant (Halobacterium)
POlHL-06314-17 0046 Immunologic mechanisms in
cardiovascular disease - Mediators of immune injury
(human, mice)
** ROlHL-12650-08 Environmental pathobiology of the lung
(hamsters, rats)
ROlHL-13596-07 Clearance of plasma proteins from
alveoli
** ROlHL-13885-08 0007 Cystic fibrosis and pulmonary
disease - Alveolar macrophage defense mechanism
(human, rabbits)
*• ROlHL-13885-08 0008 Cystic fibrosis and pulmonary
disease - Pseudomonas specific activation of alveolar
macrophages (human, rabbits)
** P50HL-141 53-07 0004 Johns Hopkins Lung Center-
Chronic diseases of airways - Macrophage enzymes in lung
injury, inflammation and repair (rabbit)
M P50HL-142 12-07 Correlated studies of pulmonary fibrosis
** P50HL-142 12-07 0004 Correlated studies of pulmonary
fibrosis • Collagen metabolism in lung tissue and lung
cells (human, animal)
" P50HL142 12-07 0006 Correlated studies of pulmonary
fibrosis - Alveolar macrophage physiology (human, rodents,
rabbits) ^ ,
** P50HL-142 12-07 0007 Correlated studies of pulmonary
fibrosis - Protein metabolism in alveolar macrophages
(rabbits, guinea pigs, human)
** P50HL-142 1207 0013 Correlated studies of pulmonary
fibrosis - Mechanism of beryllium pathogenicity in the lung
(human, rabbit, guinea pig)
RES
P50HI 1471? 0/ 0014 CorrtUUd ttudWl ol pulmon»ty
fibrosis Pulmonary lavage celU. Mcrttloni In dlHttU
intersilitnl lung disease (humin)
P50HL 14212 0/ 0015 Correlated sludie* of pulmonary
fibrosis Pulmonary defense mech.ni%m-. and tibrolir. lung
disease (rodents, rabbits)
P50HL 14212 0/ 0016 Correlated 5tudle^ of pulmonary
fibrosis Role ol pulmonary alveolar macrophages in
fibrosis (human, rabbit)
ROIHL 14262 07 Leukocyte proteases and their lung
targets (human, dogs, rabbits)
ROIHL 1466307 Pulmonary oxygen toxicity in newborn
lung (human, mice)
ROIHL 14700 05 Humoral and lung protease antiprotease
role in obstructive disease (human)
ROIHL 14778 10 Proteolytic enzymes and inhibitors in
lung disease (mammals, human)
P50HL 15061 07 0006 Response of lung to injury
Complement synthesis by pulmonary macrophages (guinea
pigs, human)
■ P50HI 15061 07 0007 Response of lung to injury
Human factors for phagocytosis in normal and diseased
lungs
' P50HL 15061 07 0009 Response of lung to injury
Alveolar macrophages (human, rabbits)
P50HL 15092 07 0002 Immune and fibrotic response to
occupational environments Longitudinal study of
sandblasters silicosis (human)
• P50HL-15092 07 0006 Immune and fibrotic response to
occupational environments Immunologic studies in
silicosis (human, rabbits, hamsters, guinea pigs)
P50HL 15092 07 0007 Immune and fibrotic response to
occupational environments Asbestosis -Cellular immunity,
structure and mineral localization (human)
P50HL 15092 07 0008 Immune and fibrotic response to
occupational environments • Animal models of asbestosis
(hamsters) . ..
•• POIHL-15832-06 0004 Chemical structural predispositions
to lung iniury Proteolytic activity leucocytes in patients
with obstructive lung disease
POlHL-15832-06 0009 Chemical structural predispositions
to lung injury • Immunology-Enzyme degradation products
of human lung elastin and microfibril
POIHL 1583206 0010 Chemical-structural predispositions
to lung injury Kinin generating systems in pulmonary
disease (human, animals)
ROlHL-16029-05 Bio-organic chemistry of ozone, nitrogen
dioxide and tobacco smoke
POlHL-161 18-06 Study of emphysema
POlHL-15118-06 0004 Study of emphysema ■ Metabolic
activity of pulmonary connective tissue (human, hamsters)
P01HL-16U8-06 0005 Study of emphysema -
Mechanisms of elastase emphysema (mice)
P01HL16137-05 0004 Alveolar biology - Subcellular
processes and controls in the surfactant system (animals)
P01HL16748-05 Cellular and immunological basis of
pulmonary diseases , .
POlHL-16748-05 0001 Cellular and immunological basis
of pulmonary diseases ■ Mechanisms of alveolar
macrophage function and dysfunction (human, rabbits)
POlHL-16748-05 0002 Cellular and immunological basis
of pulmonary diseases - Immunological function of alveolar
macrophages (rabbits, sheep, mice)
P01HL16748-05 0004 Cellular and immunological basis
of pulmonary diseases - Cellular and immunological
processes in pulmonary defense systems
POlHL-16748-05 0006 Cellular and immunological basis
of pulmonary diseases - Sarcoidosis-Studies with bronchial
lavage (human)
P01HL16769-05 Pathobiologic and host defense reactions
in the lung
• POlHL-1676905 0003 Pathobiologic and host defense
reactions in the lung - Pathobiologic mechanisms of
delayed sensitivity reactions in the lung (animals)
POlHL-16769-05 0004 Pathobiologic and host defense
reactions in the lung - Pathogenesis of Pseudomonas and
Serratia pneumonias (rabbits)
'* POlHL-16769-05 0008 Pathobiologic and host defense
reactions in the lung - Pulmonary immunocytologic defense
mechanisms against bacteria (human, animals)
" POlHL-16769-05 0009 Pathobiologic and host defense
reactions in the lung - Electron microscopy and tissue
culture core laboratory
ROlHL-16920-02 Proteases in normal and immunologically
injured lung (guinea pigs, rabbits)
POlHL-17417-05 0001 Experimental lung transplantation
- Mechanisms and mediators of lung allograft rejection
(dogs, mice)
POlHL-17417-05 0003 Experimental lung transplantation
- Methods for detecting lung allograft rejection (dogs)
R01HL17581-03 Patent ductus arteriosus and pulmonary
hypertension (dogs)
P50HL-19171-02 0007 Pulmonary SCOR-Lung injury by
childhood infections - Immunologic studies in models of
lower respiratory tract infection (rodents)
P50HL-19171-02 0009 Pulmonary SCOR-Lung injury by
childhood infections - Host-parasite interaction -Scanning
electron microscopy, freeze-fracture methods
P50HL-19190-02 0004 Pulmonary SCOR-Pathophysiology,
management of IRDS - Type II cells -Control of protein
turnover (rabbit)
(contd)
M
M
M
•Excludes routine methodology OR covers only general proiects which preclude
"Oriented significanlhi to above subject.
indexing at the specihc level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigators name and grant number.
Mitogen induced interstitial pneumonitis
RES
** ROlHL-19237-03 Obstructive lung disease and alveolar
macrophages (humanu animals)
** R01HL19429-03 Phagocytosis -Ingestion In alvelolar
macrophages (rabbits)
R23HL19584-01 Alveolar macrophage responses to toxic
particle exposure (guinea pigs, human)
R01HL19633-02 Pathogenesis and pharmacology of lung
fibrosis (rats, rabbits)
ROlHL-1965103 Host factors in pathogenesis of
respiratory disease (human, hamsters)
ROlHL-19668-03 Biochemistry of lung connective tissue
(rats)
POlHL-1971702 0003 Response of the lung to Injury ■
The role of elastolysis in emphysema (hamsters, rabbits)
POlHL-19717-02 0008 Response of the lung to injury -
Experimental models of lung disease
** POlHL-19717-02 0016 Response of the lung to injury -
The alveolar macrophage in elastase emphysema (guinea
pigs, hamsters)
** R01HL1973203 Lymphokines in pulmonary
granulomatous inflammation (mice)
ROlHL-1974103 Murine CRD-A model of chronic
pulmonary Inflammation (mice, rats)
** ROlHL-19746-03 Proliferation and differentiation of
alveolar macrophages (mice, hamsters)
" R01HL19760-01 Cellular immune responses of the lung
(mice, guinea pigs)
** ROlHL-19774-03 Pathogenesis of chronic lung disease
(rats, mice, bacteria)
** R01HL19777-03 Regulation of hypersensitivity in the lung
(rats, guinea pigs, rabbits, human)
ROlHL-19779-03 Biochemical basis of oxygen damage to
lung cells (guinea pigs, rats)
R01HL1980603 Chemotactic control of airway phagocytes
(human, rabbits)
ROlHL-19819-03
(rabbits)
ROIHL-20063-03 Pathogenesis of pulmonary mycoplasma
infections (guinea pigs, mice)
ROlHL-20095-03 Role of lymphokines and monocytes in
lung fibrosis (human, guinea pigs, rats)
ROlHL-20104-03 Pulmonary granulomatous inflammations
(mice)
'* ROlHL-2012502 Cyclic nucleotides and alveolar
macrophage activation (rabbits)
ROlHL-2035202 Defenses of lung cells against oxygen
toxicity (human, animals)
ROlHL-20566-02 Lactate metabolism in the lung (rats)
ROlHL-20675-02 Alveolar macrophage function in man
P01HL-2099402 0001 Dynamics of neutrophil elastase in
the lung ■ Dynamics of neutrophil elastase in normal
animals (dogs, rabbits)
POlHL-20994-02 0005 Dynamics of neutrophil elastase in
the lung - Protease inhibitors in pulmonary inflammation
and emphysema (rabbits)
R23HL-21 116-02 Mechanisms of membrane and tissue
damage in lung (dogs, rabbits)
** ROlHL-21 120-02 Membrane dynamics in alveolar
macrophages (rabbits)
•* ROlHL-21140-01 Studies of pulmonay alveolar
macrophage function (rabbits)
** R23HL-21251-01 Metabolism of neutral lipids in the
pulmonary alveolus (rabbits)
ROlHL-21565-02 Pathogenesis of inflammatory lung injury
(rats, rabbits)
R23HL-2199701 Pulmonary immunopathology in the
compromised host (guinea pigs)
ROlHL-22029-02 Bronchopulmonary resistance to bacterial
infection (mice)
ROlHL-22302-01 Immune responses in the human lung
(also rabbits, monkeys)
** R23HL-22437-01 Leukotactic mediators in lung
inflammatory reactions (rats, rabbits, human)
** R23HL 22823-01 Phagocytic and immune defense
mechanisms of the lung (mice)
R23HL-22895-01 Smoke inhalation-Biochemical and
cellular responses (rabbits, bacteria)
ROlHL-23211-01 Active normoxic pulmonary vasodilatation
(rat, dog, sheep)
ROlHL-23595-01 Experimental emphysema -Depression of
protease inhibitors (rats, hamsters)
ROlHL-23981-01 Acute alveolar injury (dogs)
RESPIRATORY SYSTEM, BRONCHI
** P50HL-15061-07 0005 Response of lung to injury - Airway
smooth muscle in health and disease (dogs, guinea pigs)
** POlHL-16769-05 0010 Pathobiologic and host defense
reactions in the lung - Bronchus associated lymphoid
tissue and delayed hypersensitivity (rabbits)
** POIHL- 174 17-05 0006 Experimental lung transplantation
■ Bronchial anastomotic problems and increases donor lung
availability (dog)
ROlHL-19115-02 Hormonal control of tracheobronchial
cyclic AMP (rats, guinea pigs)
P50HL-1 9160-02 0002 Mucus abnormality in cystic
fibrosis - Ultrastructure, cytochemistry of pulmonary
secretion (human, rat)
ROlHL-1943103 Regional mucociliary transport in the
human lung
POlHL-19717-02 0014 Response of the lung to injury -
Stereology of epithelialized bronchi in evolving elastase
emphysema (hamsters)
484
ROlHL-2010502 Deposition of hygroscopic aerosols in
bronchi (dogs, human, models)
ROlHL-20635-03
chick embryo)
R23HL-2 11 99-02
ROlHL-21612-02
(human, rabbits)
ROlHL-22924-01
Factors in lung development (rat and
Sound transmission in lung (dog)
Biochemistry of lung proteoglycans
The airway mucosal barrier (guinea pigs)
RESPIRATORY SYSTEM, BRONCHIAL MUCUS
" POlHL-06285-18 0189 Cardiovascular-respiratory
physiology and biochemistry - Mucociliary clearance (cats,
dogs)
** R01HL-13885-08 0009 Cystic fibrosis and pulmonary
disease - Respiratory mucus glycoproteins (human, rabbits)
ROlHL-13885-08 9002 Cystic fibrosis and pulmonary
disease Computer core facility (human)
** P50HL-14I53-07 0016 Johns Hopkins Lung Center-
Chronic diseases of airways ■ Airways defense mechanisms
(dogs)
** ROlHL-14271-07 Physico-chemical properties of tracheal
mucus (dogs, frogs)
** ROlHL-15155-05 Rheology of pulmonary secretions (dogs)
** ROIHL 16730-03 Physiology of mucociliary transport (rats.
frogs, rabbits)
** ROlHL-1777604 Pulmonary mucus transport in
obstructive lung diseases (human)
ROlHL-18308-03 Comprehensive studies of mucociliary
transport (dogs)
P50HL-191 56-02 0003 Pulmonary SCOR-Chronic diseases
of airways - Powdered tantalum to study airway morphology
and mucociliary clearance (human)
P50HL-19157-02 0002 Studies in cystic fibrosis and
bronchiolitis ■ Clinical core
P50HL-19157O2 0007 Studies in cystic fibrosis and
bronchiolitis - Analysis of cystic fibrosis factors (human)
M P50HL-19160-02 Mucus abnormality in cystic fibrosis
" P50HL-19I60-02 0001 Mucus abnormality in cystic
fibrosis - Regulation of respiratory secretions (rat, human)
** P50HL-19160-02 0002 Mucus abnormality in cystic
fibrosis - Ultrastructure, cytochemistry of pulmonary
secretion (human, rat)
** P50HLI9190-02 0005 Pulmonary SCOR -Pathophysiology,
management of IRDS ■ Glycoproteins in mucous secretions
(human, cattle)
Regional mucociliary transport in the
Pathophysiology of bronchial asthma
** ROlHL-19431-03
human lung
" ROlHL-20989-01
(sheep, dogs)
** POlHL-2099402 0006 Dynamics of neutrophil elastase in
the lung ■ Protease inhibitors in human bronchial mucus
** ROlHL-21314-02 Respiratory tract secretion of ions, water
and mucus (human, dogs)
** ROlHL-22444-01 Bronchial mucus production in organ
culture (human)
R23HL-2281801 Biosynthesis of human respiratory
mucous glycoprotein (also dog)
" ROlHL-22928-01 Systematic study of bronchial circulation
(sheep)
NOlHR-52957-02 Composition of respiratory mucus
(human, swine)
RESPIRATORY SYSTEM, BRONCHIOLE
P01HL06285-18 0188 Cardiovascular-respiratory
physiology and biochemistry - Physiology and pharmacology
in regulation of aip«ays-hyperirritability (animals)
POlHL-06285-18 0189 Cardiovascular-respiratory
physiology and biochemistry - Mucociliary clearance (cats,
dogs)
P50HL-14136-07 0004 Pulmonary SCOR-Airways
obstructive diseases - Morphometric studies of developing
emphysema (human)
ROlHL-14663-07 Pulmonary oxygen toxicity in newborn
lung (human, mice)
POlHL-15832-06 0002 Chemical-structural predispositions
to lung injury - Connective tissue in lung in development
and repair of injury (human, rats, mice)
P01HL15832-06 0012 Chemical-structural predispositions
to lung injury - Contractile structures and contractility In
cells of lung respiratory tract
ROlHL-16730-03 Physiology of mucociliary transport (rats.
frogs, rabbits)
ROlHL-1893102
(swine, human)
ROlHL-19431-03
human lung
ROlHL-20548-02
R23HL-2I539-02
Lung elastic tissue characteristics
Regional mucociliary transport in the
Innervation of the lung (rats, monkeys)
Mechanical properties of isolated small
bronchioles (rabbits)
** ROIHL-22333-01 Cellular basis of small airways function
(rats)
ROlHL-2252201 Cardioselectivity of betaadrenoceptor
antagonists
RESPIRATORY SYSTEM, COLLATERAL
RESPIRATION
" P50HL-14153-07 0017 Johns Hopkins Lung Center--
Chronic diseases of airways - Collateral ventilation and
pulmonary interdependence (pig, dog, human)
RESPIRATORY SYSTEM, GILLS
POlHL-0880515 0006 Regulation of ventilation and
pulmonary circulation Adaptation of lungfish-Estivation
RES
P01HL-I2157-11 0058 Functions and mechanisms of cell
membrane ion transport - Ionic and osmotic regulation in
toadfish -A euryhaline aglomerular teleost
ROlHL-16730-03 Physiology of mucociliary transport (rats,
frogs, rabbits)
ROlHL-17768-04 Development of collateral ventilation
(dogs. fish, horses)
RESPIRATORY SYSTEM, LARYNX
P50HL-1421407 0027 Newborn lung center for hyaline
membrane disease - Oral-laryngeal chemoreceptors and
respiratory failure in newborns (human, sheep)
ROIHL 21257-02 Breathing in sleep-Airway control and
blood gases (cats)
RESPIRATORY SYSTEM, LUNG
SEE ALSO RESPIRATORY CIRCUUTION, PULMONARY
CIRCUUTION
SEE ALSO RESPIRATORY FUNCTION
SEE ALSO RESPIRATORY SYSTEM PROSTHESIS. PROSTHETIC
LUNG
SEE ALSO RESPIRATORY SYSTEM SURGERY.
PNEUMONECTOMY
** ROlHL-01770-26 Structural aspects of lung surfactant
system (rats)
ROlHL-0295317 Autonomic and cardiovascular
pharmacology (rats, rabbits, dogs, guinea pigs)
** POlHL-0789615 0043 Environmental biomedical research
program - Effect of hyperbaric oxygen on the lung (human,
rabbits)
P01HL07896-15 0045 Environmental biomedical research
program ■ Extravascular lung water dynamics in pulmonary
oxygen toxicity (human, baboons)
POlHL-07896 15 0047 Environmental biomedical research
program • Pulmonary oxygen toxicity (chickens, rabbits)
POlHL-08805-15 0006 Regulation of ventilation and
pulmonary circulation Adaptation of lungfish-Estivation
P01HL08899-14 0025 Tolerance to respiratory gases in
health and disease - Effects of oxygen on cardiopulmonary
gas transport functions (dogs)
" POlHL-0889914 0056 Tolerance to respiratory gases in
health and disease - Extension of pulmonary oxygen
tolerance at increased pressures (animals)
** POlHL-1141411 0028 Thrombosis and atherosclerosis
program - Catecholamine metabolism in the lung (rat)
ROIHL 12879-09 0002 Pulmonary transport and
metabolism in vivo - Osmotic compartmental model of
barrier exchange
ROlHL-12879-09 0006
metabolism in vivo
ROlllL-12879-09 0010
metabolism in vivo
•Excludes routine methodology OR covers only general projects which preclude indexing
**0riented significantly to above subject.
at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number
Pulmonary transport and
The missing sodium
Pulmonary transport and
Lung morphometry in control and
edematous lungs (dogs)
ROlHL-12879-09 0011 Pulmonai> transport and
metabolism in vivo - Membrane characteristics of lung
cells (human, animals)
R01HL12974-10 Tracer kinetics, flows and masses in
body organs (human, dogs)
ROlHL-13315-08 Disposition of vasoactive hormones in
mammalian lung (rats, rabbits, human)
' ROIHL 13405-09 Regulation of lipid metabolism in the
lung (rats)
ROlHL-13921-07 The lung as a metabolic organ (animals)
P50HL-14153-07 0004 Johns Hopkins Lung Center-
Chronic diseases of airways - Macrophage enzymes in lung
injury, inflammation and repair (rabbit)
' P50HL-14153-07 0015 Johns Hopkins Lung Center-
Chronic diseases of airways - Kinins and human lung
P50HL1418707 0012 Pulmonary SCOR -Chemical
mediators in pulmonary vascular responses - Vasoactive
mediators in pulmonary disease (human, animal)
P50HL-14187-07 0014 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses ■ Metabolism
and actions of vasoactive peptides in lung (human,
mammals)
P50HL-14212-07 0004 Correlated studies of pulmonary
fibrosis - Collagen metabolism in lung tissue and lung
cells (human, animal)
P50HL-14214-07 0015 Newborn lung center for hyaline
membrane disease - Hormone effect on cyclic nucleotide
lipid synthesis in developing lung (animal)
P50HL-142 14-07 0020 Newborn lung center for hyaline
membrane disease - Epidermal growth factor effect-Lung
differentiation, maturation (human, rabbit)
P50HL-14214-07 0021 Newborn lung center for hyaline
membrane disease - Development of surfactant system-
Surfactant production and release (rat, rabbit)
P50HL-142 14-07 0023 Newborn lung center for hyaline
membrane disease - Regulation of fetal lung maturation-
Vitamin A (rat, rabbit, sheep, human)
P50HL14214-07 0024 Nev»born lung center for hyaline
membrane disease - Synthesis and receptors for ACTH in
fetal lung (human)
P50HL-14214-07 0025 Newborn lung center for hyaline
membrane disease - Pulmonary vascular permeability and
lung water-Hyaline membrane disease (sheep)
P50HL-14218-07 0006 Pulmonary SCOR -Newborn lung
center - Biochemical characteristics of the lung in RDS
(human, sheep)
ROlHL-14262-07 Leukocyte proteases and their lung
targets (human, dogs, rabbits)
(contd)
RES
POIHL 143880? Olbb Regulation ot the circulation in
patl<olo|lcat states Cardiopulmonary ellerent activity,
carotid cl\emoubaroreceplor reflexes
POIHL 14414 07 0008 Environmental inlluencas on
cartloraspiratory and cellular lunctions tnerjetlcs ot
swin\mini (human)
• ROIHL 14456 07 Lung metabolism Inrymes in the
pulmonary ciiculation (human, animals)
'• ROIHL 1449b 05 Solid and structural mechanics ot lungs
(mammals) . ~
•• POIHL 14580 07 0001 Program prelect in respitatr^iy
mechanics Micromechanics ot the lung (dogs, rats)
POIHL 14580 07 0002 Program project in respiratory
mechanics Airviay aerodynamics (human, dogs)
POIHL 1458007 0005 Program project in respiratory
mechanics Development and evaluation of tests of
pulmonary function (human)
*• ROIHL 14663 07 Pulmonary oxygen toxicity in newborn
lung (human, mice)
•* ROIHL 14854 07 Lung and tissue mechanics (monneys.
dogs)
•* ROIHL 1501307 Lung oxidative metabolism and energy
production (rodents, rabbits)
•• P50HL 15061 07 0002 Response of lung to injury ■
Oxidative metabolism, phospholipid synthesis, and response
to toxins (rats)
R01HL15273-06 Metabolism of pulmonary surlactant
(human, rats)
•* ROIHL 1534106 Lung hormonal and chromosomal
regulation (rats, rabbits)
ROIHL 1565505 Blood flov» and gas exchange in placenta
and lungs (sheep) rabbits)
•* P01HL15832 06 0002 Chemical structural predispositions
to lung injury ■ Connective tissue in lung in development
and repair of injury (human, rats, mice)
•* P01HL15832-06 0005 Chemical-structural predispositions
to lung injury ■ Pulmonary structure and stress-strain
relationships (rats)
** POlHL-15832-06 0007 Chemical-structural predispositions
to lung injury - Inactivation of vasoactive agents by the
lung (human, rats, cats, dogs)
•* POlHL-15832-06 0009 Chemical-structural predispositions
to lung injury ■ Immunology-Enzyme degradation products
of human lung elastin and microfibril
•* POlHL-15832-06 0011 Chemical-structural predispositions
to lung injury - Interaction of cell receptors with vasoactive
agents in pulmonary vascular bed
*• POlHL-15832-06 0012 Chemical-structural predispositions
to lung injury - Contractile structures and contractility in
cells of lung respiratory tract
*• POIHL 15832-06 9001 Chemical-structural predispositions
to lung injury - Tissue culture studies of lung cell function-
-Core facility
IVI POlHL-16118-06 Study of emphysema
POlHL-161 18-06 0003 Study of emphysema - Degradation
of collagen and elastin (human, hamsters, mice)
ROlHL-16330-06 Aging-tissue injury and repair (rats)
ROlHL-16430-05 Neural control of respiration (cats)
ROlHL-16730-03 Physiology of mucociliary transport (rats,
frogs, rabbits) ,
POlHL-16769-05 0010 Pathobiologic and host defense
reactions in the lung - Bronchus associated lymphoid
tissue and delayed hypersensitivity (rabbits)
POlHL-16769-05 0011 Pathobiologic and host defense
reactions in the lung - Core -Laboratory for biomedical
preparation (rabbits)
•* ROlHL-16916-04 0001 The role of albumins in lung water
accumulation - Capillary permeability (dogs, human)
•* ROlHL-16916-04 0002 The role of albumins in lung water
accumulation - Lung water balance-Forces, models and
albumin concentrations (rabbits, dogs)
** ROlHL-16920-02 Proteases in normal and immunologically
injured lung (guinea pigs, rabbits)
** ROlHL-17322-04 Functional characteristics of smooth
muscle isolated from lung (animals)
POlHL-17382-05 0002 Chemical mediators of acute
pulmonary disorders - Chemical mediators and respiratory
mechanics in guinea pigs
ROlHL-17503-03 Vascular bubbles in decompression
sickness (minipig, dog, goat)
POlHL-17731-04 0011 Physiological basis of pulmonary
disease - Ivlorphometric studies of the lung-Core
ROlHL-17826-04 Oxygen delivery to tissue (rat, dog)
** ROlHL-17967-04 Limiting factors in oxygen uptake in the
** ROlHL-18260-04 Cyclic nucleotide metabolism in lung
tissue (cattle)
** ROlHL-18526-03 Kinins and the human lung
ROlHL-18607-03 tJletabolic and drug studies on
experimental fat embolism (mice)
ROlHL-18639-03 Human anatomy for cardiac prostheses
(human)
** ROlHL-18826-04 Interaction of peptides and target cells
in lung (human)
** ROlHL-18931-02 Lung elastic tissue characteristics
(swine, human)
•* R01HL-18938-03 Pulmonary fatty acid and phospholipid
metabolism (rats)
*♦ ROlHL-18952-03 li/letabolism in perfused fetal and
newborn rabbit lungs
** ROlHL-19008-02 Carbon dioxide diffusion in lung and
muscle tissues (dogs)
485
ROIHI 19056 03 Blood triglycerides and lipoprotein lipase
in the lung (rats)
P50HI 19155 02 0005 Pathophysiology of pulmonary
edema Protein exchange sites and lymph protein
concentration in lung (mice, sheep)
P50HL 19160 02 0002 Mucus abnormality in cystic
fibrosis Ultrastructure, cytochemistry of pulmonary
secretion (human, rat) , : „ ku
P50HI 19171 02 0010 Pulmonary SCOR lung Injury by
childhood infections Metabolic pathways ot normal and
injured respiratory cells
P50HL 1918502 0003 Pulmonary SCOR Neonatal
respiratory distress syndromes Factors affecting formation
and release of pulmonary surfactant in fetal lambs
P50HL 1918502 0004 Pulmonary SCOR Neonatal
respiratory distress syndromes Fluid and protein transport
in fetal and newborn lung (sheep, rabbits)
«• P50HL 1918502 0005 Pulmonary SCOR Neonatal
respiratory distress syndromes Role and mechanism o
glucocorticoids in fetal lung maturation (human, rabbit
P50HL 19187 02 0001 Pediatric pulmonary SCOR Hyaline
membrane disease Hyaline membrane disease-Changes
in lung mechanics and gas exchange (monkeys)
P50HL 19187-02 0003 Pediatric pulmonary SCOR Hyaline
membrane disease Hyaline membrane disease-
Ultrastructure studies (monkey)
*• ROIHL 19379-03 Characterization of small granule cells in
the lung (mammals) ; i
•* R23HL-19573-01 Studies on pulmonary serotonin (mice)
** R23HL-19594 01 Tropocollagen and tropoelastin uptake in
lung cells (human)
" R23HL-19605-01 Lipid requirement of the lung mono-
oxygenase system (rabbits)
" ROIHL 19654 03 Biochemical-pharmacological evaluation
of lung cells (rabbits)
•• ROlHL-19668-03 Biochemistry of lung connective tissue
(rats) ( „„
** ROlHL-19684-03 Histotypic lung culture in circumtusion
systems (mice)
" POlHL-19717 02 0001 Response of the lung to injury -
Lung elastic tissue (animals)
** POlHL-197 17-02 0002 Response of the lung to in)ury -
Prolyl hydroxylase, lysyl hydroxylase and lung collagen
biosynthesis (rabbits) . .
•* POlHL-197 17-02 0004 Response ot the lung to injury -
Regulatory and physical-chemical properties of lung lysyl
oxidase (animals) . ,
•• POlHL-197 17-02 0006 Response of the lung to injury -
Glycosaminoglycans and proteoglycans of the lung (human,
rats, hamsters) . .
*• POlHL-197 17-02 0009 Response of the lung to injury -
Time-dependent mechanical properties of lung connective
tissues (hamsters)
POlHL-197 17-02 0012 Response of the lung to injury -
Connective tissue biochemistry and enzyme injury of the
lung (hamsters) . „
" POlHL-197 17-02 0020 Response of the lung to injury ■
Recording of lung sounds in animal models of disease
(animals) , .
** P01HL197 17-02 0023 Response of the lung to injury -
Postnatal lung development -Cells, connective tissue and
physiology (animals)
POlHL-19737-02 0013 Cellular and molecular aspects of
respiratory physiology - Cell metabolism analytical facili^
** ROlHL-19779-03 Biochemical basis of oxygen damage to
lung cells (guinea pigs, rats)
** ROlHL-19836-03 Kinin inhibitors detected by use ot
receptors (cattle)
** ROlHL-201 32-03 Histogenesis and biochemistry of
embryonic lung (birds)
** R01HL-20344-02 Regulation of protein turnover in lung
tissue (rats) .
*• ROlHL-20548-02 Innervation of the lung (rats, monkeys)
" ROlHL-20566-02 Lactate metabolism in the lung (rats)
** ROlHL-20622-02 Pulmonary uptake and accumulation of
drugs (rabbits, rats)
" ROlHL-2063503 Factors in lung development (rat and
chick embryo) .u ■ ■
ROlHL-20868-02 Regulation of glycoprotein biosynthesis in
lung (swine)
R01HL-20875-02 Chronic obstructive pulmonary disease-
Familial/genetic (human)
POlHL-20994-02 0002 Dynamics of neutrophil elastase in
the lung - Neutrophil and neutrophilic elastase in human
POlHL-20994-02 0009 Dynamics of neutrophil elastase in
the lung - Biosynthesis and degradation of elastin in
emphysema (human, hamsters)
*• ROlHL-21008-02 Effect of pollutants on organotypic lung
cultures (rats)
•* ROlHL-21076-02 Lung fluid, protein exchange alter
hemorrhagic shock (sheep)
*♦ R23HL-2108902 Localization of mediators in dispersed
lung cells (guinea pigs, human)
** R23HL-21116-02 Mechanisms of membrane and tissue
damage in lung (dogs, rabbits)
ROlHL-211 17-01 Altitude adaptation in chronic lung
disease (human) ^ ,^ , , »
"■ R23HL-21189 01 Regulation of pulmonary endothelial ceii
activities (human, cattle)
** R23HL-21199-02 Sound transmission in lung (dog)
RES
R23HI 21225 02 Conntcttv* tlitu* pttcurwf n)Ol.cul«» m
the lung (rabbiti. hini«l«r»)
ROIHI 21394 02 Pulmonary angiotensin converlini •n/ym«
' R23HL 21396 02 Isolation, growth and roetabolnm ot type
1 pneumocytes (rabbits)
R23HL 21409 02 Perinatal control of the ductus arterioiui
• ROl HI 21444 02 Pulmonary mechanics during postnatal
development (human) „.„..
• POIHL 21584 02 0001 Respiratory mechanics in normal
and abnormal states Engineering analysis of lung
deformation (human, animals)
• ROIHL 21612 02 Biochemistry of lung proteoglycans
(human, rabbits)
ROIHL 2161501 Structural studies ot lung heparinoid
polysaccharides (cattle)
•• ROIHL 21617 02 Biochemistry ot lung proteoglycans
(rabbits, cattle)
'• ROIHL 21622 02 Structure and interactions ot lung
proteoglycans (cattle)
•• ROIHL 21626 01 Proteoglycans of animal lung
parenchyma (cattle, pigs, rabbits)
•• ROIHL 21641 02 Structural studies of lung proteoglycans
(pigs, cattle, rabbits)
•• ROIHL 21646-02 Biosynthesis of fractionated
proteoglycans of lung (rabbits)
*• ROIHL 21649 01 Biochemistry of lung proteoglycans
(mammals) , . ,.^
•* R23HL-21855-01 Mathematical models ot branching in the
human lung „„^~«
— R23HL-21894-01 Pulmonary angiotensin converting enzyme
(cattle)
R23HL-21943-01 Capillary morphology in pulmonary
edema (dogs) . _ ,.
R23HL 22011-01 Adrenergic receptor cyclase system in
sensitized lung (rats, guinea pigs)
** R13HL-22159-01 Conference on non-ventilatory functions
of the lungs (New Hampshire)
** ROlHL-22 178-01 Lung airway properties by acoustic
impulse reflection
ROlHL-22242-01 The converting enzyme of lung (canie,
human) ^ , ., •
•* ROlHL-22266-01 Production of proteases by lung cells in
culture (human, rodents, rabbits, sheep)
** ROlHL-22313-01 Lung elastic recoil -Age and disease
(human)
R23HL-22346-01 Hematological injury and pulmonary
dysfunction (human, mammals)
** ROlHL-22500-01 Conversion of choline to
phosphatidylcholine in lung (rabbits, pigs)
ROlHL-22527-01 Prostacyclin-thromboxanes in the
cardiovascular system (human, rabbits)
ROlHL-22555-01 Structure and function of platelet
activating factor (rabbits, human)
** R23HL-22823-01 Phagocytic and immune defense
mechanisms of the lung (mice)
ROlHL-23981-01 Acute alveolar injury (dogs)
ROlHL-23985-01 Role of the diaphragm in regional lung
mechanics (dogs)
** N01HR-32902-07 Pilot study to standardize the
measurement of closing volume (human)
NOlHR-62910-02 Fibroprotcin networks of pulmonary
alveolar wall (human)
** NOlHR-62930-03 Lung cell resource facility
RESPIRATORY SYSTEM, LUNG ALVEOLUS
** POlHL-06285-18 0208 Cardiovascular-respiratory
physiology and biochemistry - Composition, properties and
turnover ot pulmonary surfactant (human, animals)
" POlHL-06285-18 0209 Cardiovascular-respiratory
physiology and biochemistry ■ Metabolic studies of isolated
lung cells (human, animals)
POlHL-06370-17 0006 Cardiopulmonary and renal
pathology research center - Chemical basis of
ultrastructural changes in disease (rats)
" POlHL-06664-17 0043 Cardiopulmonary function in
remediable vascular disease - Alveolar hypoxic
vasoconstriction-Control and clinical significance (dog,
human) .
POlHL-07896-15 0021 Environmental biomedical researcn
program - Liquid breathing and lung lavage (human)
POlHL-07896-15 0039 Environmental biomedical research
program - Development of resistance to lethal effects of
oxygen (rats) .
** P01HL07896-15 0058 Environmental biomedical researcn
program - Lung synthesis of disaturated
phosphatidylcholine (rats, dogs, bats)
POlHL-08805-15 0025 Regulation of ventilation and
pulmonary circulation - Pulmonary edema (rabbits)
** POlHL-08805-15 0042 Regulation ot ventilation and
pulmonary circulation - Electron microscope core research
laboratory
** POlHL-08805-15 0048 Regulation ot ventilation and
pulmonary circulation - Permeability ot alveolo-Capillaiy
membrane in normal pulmonary hypertensive lung
POlHL-08899-14 0038 Tolerance to respiratory gases in
health and disease - Brain vessels change in alveolar
arterial gas tensions (human, monkeys)
" ROlHL-13405-09 Regulation of lipid metabolism in the
lung (rats)
*• ROlHL-13596-07 Clearance of plasma proteins from
alveoli
(contd)
•Excludes routine methodology OR covers only general projects which preclude
••Oriented significantly to above subject.
indexing atthespecihc level.
M Grant has subprojects descnbing specific research aspects.
See Appendix for Investigators name and grant number.
RES
ROlHL-13901-08 Ontogeny, ultrastructure, function in
lymphatic system (birds, fish, mammals)
P50HL14187-07 0015 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses -
Pathophysiologic responses of pulmonary capillary bed
(dog, human)
P50HL-U214-07 0021 Newborn lung center for hyaline
membrane disease ■ Development of surfactant system-
Surfactant production and release (rat, rabbit)
" P50HL-14214-07 0022 Newborn lung center for hyaline
membrane disease ■ functional integrity of surfactant
system-Hyaline membrane disease (lamb, rat)
P50HL-14218-07 0017 Pulmonary SCOR-Newborn lung
center - Transvascular fluid exchange, vasoactive mediators
in RDS (sheep, cat)
** P01HL14414-07 0003 Environmental influences on
cardiorespiratory and cellular functions ■ Exposure to
abnormal gaseous environments (human, dogs, rabbits)
R01HL14854-07 Lung and tissue mechanics (monkeys,
dogs)
R01HL1501307 Lung oxidative metabolism and energy
production (rodents, rabbits)
P01HL15194-07 UOU Pathophysiology of
cardiopulmonary dysfunction ■ Distribution of ventilation-
Oxygen effects on intrapulmonary shunting (human)
ROlHL-15316-07 Lung surfactant system -Control
mechanisms (rats)
POIHLI 5832-06 0002 Chemical-structural predispositions
to lung injury - Connective tissue in lung in development
and repair of injury (human, rats, mice)
POlHL-15832-06 0005 Chemical structural predispositions
to lung injury - Pulmonary structure and stress-strain
relationships (rats)
POlHL-15832-06 0012 Chemical-structural predispositions
to lung injury - Contractile structures and contractility in
cells of lung respiratory tract
P01HL-16I 18-06 0005 Study of emphysema -
Mechanisms of elastase emphysema (mice)
M POlHL-16137-05 Alveolar biology
** POlHL-16137-05 0008 Alveolar biology ■ Macromolecular
events in pulmonary cells in toxic environments (animals)
** POlHL-16137-05 0013 Alveolar biology - Development and
pathology of surfactant-Formation of alveolar (rabbits,
sheep)
** ROlHL-16674-05 Airborne metals and lung permeability
(bullfrogs, rats)
R01HL16725-03 Physiological regulation of pulmonary
surfactant (dogs, rats)
ROlHL-16784-03 Lung tissue and water volume (human,
dogs)
ROIHL- 1 7358-04 Ventilatory adjustments for optimal
oxygenation (dogs, rats)
*• POlHL-l 74 17-05 0001 Experimental lung transplantation
- Mechanisms and mediators of lung allograft rejection
(dogs, mice)
POlHL-17417-05 0003 Experimental lung transplantation
- Methods for detecting lung allograft rejection (dogs)
R01HL17719-03 Lung injury, substrate utilization, oxygen
toxicity (rats, rabbits, dogs)
" POlHL-17731-04 0002 Physiological basis of pulmonary
disease - Biomechanics of the lung (frogs, cats)
ROlHL-18181-04 Surfactant metabolism-Alveolar cells and
lung disease (mice, rabbits)
ROlHL-19008-02 Carbon dioxide diffusion in lung and
muscle tissues (dogs)
" R01HL19010-03 Metabolism and cell b^logy of lung
surfactant system (rabbits, sheep)
ROlHL-19018-03 Etiologic factors in cryptogenic fibrosing
alveolitis (human)
P50HL-19155-02 0002 Pathophysiology of pulmonary
edema - Non-invasive measurement of protein turnover in
human lung (also sheep)
P50HL 19155-02 0005 Pathophysiology of pulmonary
edema - Protein exchange sites and lymph protein
concentration in lung (mice, sheep)
P50HL-19160-02 0002 Mucus abnormality in cystic
fibrosis - Ultrastructure, cytochemistry of pulmonary
secretion (human, rat)
P50HL-19185-02 0001 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Sites of synthesis,
secretion and structure of surface active material (rat)
P50HL19185-02 0002 Pulmonary SCOR-Nconatal
respiratory distress syndromes - Biochemistry,
ultrastructure-Pulmonary surface active material (human,
animal)
•• P50HL-1918702 0003 Pediatric pulmonai> SCOR-Hyaline
membrane disease - Hyaline membrane disease-
Ultrastructure studies (monkey)
P50HL-19137-02 0004 Pediatric pulmonary SCOR-Hyaline
membrane disease ■ Hyaline membrane disease-Surface
active material, lamellar bodies (mice, rats)
M P50HL-19190-02 Pulmonary SCOR-Pathophysiology,
management of IRDS
Pulmonary SCOR-Pathophysiology,
Type II cells-Regulation and
P50HL-19I90-02 0003
management of IRDS
differentiation (rat)
P50HL-19190-02 0004
management of IRDS
turnover (rabbit)
ROlHL-19225-02 0001
pulmonary hypertension
animals)
Pulmonary SCOR-Pathophysiology,
Type II cells-Control of protein
Types and mechanims of
- Structural changes (human.
486
ROlHL-19225-02 0002 Types and mechanims of
pulmonary hypertension - Effect of aorto-pulmonary shunt
(pigs)
P50HL-19362-02 0008 A/S SCOR -Atherosclerosis in
nonhuman primates - Lung structure and function in
cigarette smoking (baboon)
ROlHL-19684-03 Histotypic lung culture in circumfusion
systems (mice)
POlHL-197 17-02 0005 Response of the lung to injury -
Studies on proteolysis and lung disease (human, animals)
POlHL-197 17-02 0007 Response of the lung to injury -
Cellular level studies of prostaglandin-like molecules
(cattle)
POlHL-197 17-02 0014 Response of the lung to Injury -
Stereology of epithelialized bronchi in evolving elastase
emphysema (hamsters)
POlHL-19717-02 0024 Response of the lung to injury -
Formation of lung alveoli (rats)
POlHL-19717-02 0025 Response of the lung to injury -
Role of oxygen in regulation of lung growth and
development (rats)
POlHL-197 17-02 0026 Response of the lung to injury -
Protein depletion and postnatal lung development (rats)
POlHL-19717-02 0027 Response of the lung to injury -
Hormone control of lung growth and development (rats)
POlHL-197 17-02 0028 Response of the lung to injury -
Compensatory growth of the lung following pneumonectomy
(rabbits)
Cellular and molecular aspects of
Fatty acid metabolism in type II
Cellular and molecular aspects of
Cortisol-dependent alterations in
Airway turbulence and pulmonary oxygen
Sites of leakage in pulmonary edema
Surfactant, pulmonary edema, and lung
* POlHL-19737-02 0001
respiratory physiology
alveolar cells (rats)
* POlHL-19737-02 0003
respiratory physiology
lung type II cells (rats)
POlHL-19737-02 0005 Cellular and molecular aspects of
respiratory physiology - Interaction of respiratory exchanges
and blood gas parameters (human, animals)
ROlHL-20366-03 Protein turnover and amino acid
transport by lung (rats)
R23HL-20576-01
exchange
ROlHL-20652-01
(dogs)
ROlHL-20773-02
mechanics (rabbits)
POlHL-20994-02 0001 Dynamics of neutrophil elastase in
the lung - Dynamics of neutrophil elastase in normal
animals (dogs, rabbits)
POlHL-209 94-02 0007 Dynamics of neutrophil elastase in
the lung - The etiology of experimental emphysema (dogs)
ROlHL-21008-02 Effect of pollutants on organotypic lung
cultures (rats)
ROlHL-21009-02
culture (rats)
R23HL-21050-02
edema (rabbits)
ROlHL-21095-02 Enzymes of M tuberculosis and
obstructive lung disease (human, rodents)
R23HL-21 116-02 Mechanisms of membrane and tissue
damage in lung (dogs, rabbits)
ROIHL 21 176-02 Phospholipid exchange proteins in lung
tissue (lambs)
R23HL-212 12-02 Alveolar macrophage function In
Pseudomonas infection (dgs)
R23HL-21251-01 Metabolism of neutral lipids in the
pulmonary alveolus (rabbits)
ROlHL-21376-02 Blood-gas barrier solute and water
transport (rabbits)
R23HL-21396-02 Isolation, grovrth and metabolism of type
1 pneumocytes (rabbits)
ROlHL-21568-02 Cell biology of the alveolar-capillary unit
(animals)
R23HL-21853-01 Lung metabolism and alveolo-capillary
permeability (rats)
ROlHL-22435-02 Pulmonary alveolar-capillary permeability
characteristic (dogs)
ROlHL-22463-02 Pinocytotic vesicles and pulmonary
Effects of air pollutants on lung cells in
Mechanisms of re-expansion pulmonary
edema (rats)
ROlHL-22549-02
membrane (dogs)
ROlHL-22552-02
disease (sheep)
ROlHL-22843-01
(lambs)
ROlHL-22883-01
ROlHL-22911-01
fluid (dogs)
R23HL-22932-01
exchange (dogs)
ROlHL-23969-01
vitro (rats)
ROlHL-23981-01
NOlHR-629 10-02
Transport across alveolar capillary
Abnormal alveolar permeability and lung
Pulmonary physiology in liquid ventilation
Lung epithelial cell interactions in vitro
Mechanism of clearance of lung edema
Effect of carbon dioxide on local gas
Surfactant synthesis by type II cells in
Acute alveolar injury (dogs)
Fibroprotein networks of pulmonary
alveolar wall (human)
RESPIRATORY SYSTEM, PULMONARY STRETCH
RECEPTORS
ROlHL-06143-18 Response of the totally denervated heart
to exercise (dogs)
POlHL-06285-18 0180 Cardiovascular-respiratory
physiology and biochemistry - Vagal C-fibers and their
influence on visceral and somatic function (animals)
RES
PaiHL-10436-13 0014 A multidisciplinaiy study of
congenital heart disease - Cardiovascular pharmacology
(dog)
ROlHL-13888-15 Regulation of respiration
POlHL-14985-07 0004 Adaptation to hypoxia - Control of
breathing in respiratory failure (human, dogs)
POlHL-14985-07 0008 Adaptation to hypoxia - Ventilatoiy
drive and exercise capacity (human, dogs)
ROlHL-16430-05 Neural control of respiration (cats)
P01HL16878-05 0003 Control of ventilation in health
and disease - Brain stem respiratory neurons in response
mechanical/chemical loading (animal)
P50HL 19156-02 0005 Pulmonaof SCOR -Chronic diseases
of airv»ays - Vagal receptors in the airway-Epithelial injury
and antigen (dog, cat, rabbit)
ROIHL 19827 02 Role of the upper airways in the control
of breathing (human, cats, dogs)
** ROlHL-20122-02 Operational mechanisms of airway
receptors (dogs, pigs)
** R23HL-21042-01 Cardiopulmonary reflexes and their
anatomical basis (dogs)
POlHL-21584-02 0005 Respiratory mechanics in normal
and abnormal states - Regulation and behavior of airway
smooth muscle (human, animals)
RESPIRATORY SYSTEM, PULMONARY
SURFACTANT
** ROlHL-0 17 70-26 Structural aspects of lung surfactant
system (rats)
** POlHL-06285-18 0208 Cardiovascular-respiratory
physiology and biochemistry - Composition, properties and
turnover of pulmonary surfactant (human, animals)
** POlHL-06285-18 0209 Cardiovascular-respiratory
physiology and biochemistry - Metabolic studies of isolated
lung cells (human, animals)
** POlHL-06285-18 0210 Cardiovascular-respiratory
physiology and biochemistry - Physicochemical and
enzymatic studies of lung surfactant (Halobacterium)
POlHL-06285-18 0213 Cardiovascular-respiratory
physiology and biochemistry - Membrane structure and
function -Gas vacuole membrane (Halobacterium)
** ROlHL-12650-08 Environmental pathobiology of the lung
(hamsters, rats)
** ROlHL-13405-09 Regulation of lipid metabolism in the
lung (rats)
P50HL-14136-07 0001 Pulmonary SCOR-Airways
obstructive diseases - Experimental airway obstructive
disease (dogs)
P50HL-14153-07 0016 Johns Hopkins Lung Center-
Chronic diseases of airways - Airways defense mechanisms
(dogs)
P50HL 14212-07 0014 Correlated studies of pulmonary
fibrosis - Pulmonary lavage cells, secretions in diffuse
intersititial lung disease (human)
P50HL-14214-07 0015 Newborn lung center for hyaline
membrane disease - Hormone effect on cyclic nucleotide
lipid synthesis in developing lung (animal)
P50HL-14214-07 0020 Newborn lung center for hyaline
membrane disease - Epidermal growth factor effect -Lung
differentiation, maturation (human, rabbit)
** P50HL-14214-07 0021 Newborn lung center for hyaline
membrane disease - Development of surfactant system-
Surfactant production and release (rat, rabbit)
** P50HL-14214-07 0022 Newborn lung center for hyaline
membrane disease - Functional integrity of surfactant
system-Hyaline membrane disease (lamb, rat)
P50HL-14214-07 0030 Newborn lung center for hyaline
membrane disease - Effects of ductal patency-Impedance
cardiography and echocardiography (human)
ROlHL-14262-07 Leukocyte proteases and their lung
targets (human, dogs, rabbits)
ROlHL-14844-06 Mucous glycoprotein in human respiratoiy
epithelium (also wheat)
ROlHL-14854-07
dogs)
** ROlHL-15273-06
(human, rats)
Lung surfactant system-Control
Lung and tissue mechanics (monkeys.
Metabolism of pulmonary surfactant
•Excludes routine methodotogy OR covers only general projects which preclude indexing
"Oriented significantly to above subject.
at the specific level.
M Grant has subprojects describing specific research aspects
See Appendix for investigator's name and grant number.
ROlHL-15316-07
mechanis.ns (rats)
POlHL-15832-06 0005 Chemical-structural predispositions
to lung injury - Pulmonary structure and stress-strain
relationships (rats)
POlHL-16137-05 Alveolar biology
POlHL-16137-05 0001 Alveolar biology - Chemical
characterization of surfactant system-Lipid and lipid
protein fractions
P01HL16137-05 0004 Alveolar biology - Subcellular
processes and controls in the surfactant system (animals)
POlHL-16137-05 0008 Alveolar biology ■ Macromolecular
events in pulmonary cells in toxic environments (animals)
POlHL-16137-05 0013 Alveolar biology - Development and
pathology of surfactant-Formation of alveolar (rabbits,
sheep)
ROlHL-16725-03 Physiological regulation of pulmonary
surfactant (dogs, rats)
POIHL- 16748-05 0001 Cellular and immunological basis
of pulmonary diseases ■ Mechanisms of alveolar
macrophage function and dysfunction (human, rabbits)
POlHL-16748-05 0004 Cellular and immunological basis
of pulmonary diseases ■ Cellular and immunological
processes in pulmonary defense systems
(contd)
RES
POIHL 1676905 0009 Pithobcoloiic ind host delensn
ructions in th« luni Electron microscopy and tissue
cultuce cote libotatory
ROIHL 18181 04 SutlectanI metabolism Alveolar cells ano
lung disease (mice, rabbits) ,. , ^
ROIHL 1893803 Pulmonary tatty acid and phospholipid
metabolism (cats)
ROIHI 1901003 Metabolism and cell bioloH ol lunj
suflactant system (rabbits, sheep)
ROIHI 190S6 03 Blood trijlycerides and lipoprotein lipase
in the lunj (rats)
PSOHl 19171 02 0010 Pulmonary SCOR Lung iniury by
childhood inlections Metabolic pathways ol normal and
injured respiratory cells
P50HL 1918502 Pulmonary SCOR Neonatal respiratory
distress syndromes
P50HL 19185 02 0001 Pulmonary SCOR Neonatal
raspiratorY distress syndromes Sites ot synthesis.
secretion and structure ot surlace active material rat)
• P50H11918502 0002 Pulmonary SCOR Neonatal
respiratory distress syndromes Biochemistry,
ultrastructure Pulmonary surlace active material (human.
animal) „„ „ , ,
• P50HL 19185-02 0003 Pulmonary SCOR Neonatal
respiratory distress syndromes Factors aHectmg formation
and release ot pulmonary surfactant in tetal lambs
P50HL 1918502 0005 Pulmonary SCOR Neonatal
respiiatoiy distress syndromes Role and mechanism of
glucocorticoids in tetal lung maturation (human, rabbit)
P50HL 19185-02 0006 Pulmonary SCOR Neonatal
respiratory distress syndromes Evaluation ot risk factors
in neonatal respiratory distress (human, sheep)
P50HL 19187-02 Pediatric pulmonary SCOR -Hyaline
membrane disease
P50HL 1918702 0001 Pediatric pulmonary SCOR-Hyaiine
membrane disease - Hyaline membrane disease- Changes
in lung mechanics and gas exchange (monkeys)
** P50HL-1918702 0002 Pediatric pulmonary SCOR -Hyaline
membrane disease Hyaline membrane disease -Alterations
in surface active material (monkeys)
P50HL-19187-02 0003 Pediatric pulmonary SCOR- Hyaline
membrane disease - Hyaline membrane disease
Ultrastructure studies (monkey)
** P50HL-19187-02 0004 Pediatric pulmonary SCOR -Hyaline
membrane disease - Hyaline membrane disease-Surface
active material, lamellar bodies (mice, rats)
M P60HL-1919O-02 Pulmonary SCOR -Pathophysiology,
management of IROS .
*• P50HL-19190-02 0003 Pulmonary SCOR -Pathophysiology,
management of IRDS - Type II cells-Regulation and
differentiation (rat) „ „ ^ u i „„
♦• P50HL-19190-02 0004 Pulmonary SCOR-Pathophysiology.
management of IRDS - Type II cells -Control of protein
turnover (rabbit)
ROlHL-19195-03 Hormonal regulation of lung function
(rats) J J . .
•• ROlHL-19669-03 Lung organ culture and surtactant
biosynthesis (adult and fetal rats)
•* ROlHL-19676-02 Physico-chemical interactions in
pulmonary surfactant , ,u i „„
R01HL-19685-03 Pathogenesis of inflammation ot the lung
Cellular and molecular aspects of
Fatty acid metabolism in type II
M
.»H/
ROIHI 23981 01 Atulc .ilvpoUc mluiy (dogs)
RESPIRATORY SYSTEM, TRACHEA
Srt Also RfSPIRAIORY OlSOROtRS, lARYNGOIRACHEIIlS
POIHL 06285 18 0189 Cardiovascular respiratory
physiology and biochemistry Mucociliary clearance (cats.
P50HL 141530/ 0016 lohns Hopkins Lung Center
Chronic diseases ol airways Airv.ays defense mechanisms
•• P50HL 15061 07 0005 Response of lung to inlury Airway
smooth muscle in health and disease (dogs, guinea pigs)
ROIHL 16730 03 Physiology ol mucociliary transport (rats.
Irogs. rabbits) , . ,
ROIHL 191 15 02 Hormonal control ol tracheobronchial
cyclic AMP (rats, guinea pigs)
P50HL 1916002 0002 Mucus abnormality in cystic
libiosis Ultrastructure. cytochemistry ol pulmonary
secretion (human, rat)
P50HL 19171 02 0009 Pulmonary SCOR Lung inlury by
childhood inlections Host parasite interaction Scanning
electron microscopy. Ireeje Iracture methods
P50HL 19171-02 0010 Pulmonary SCOR Lung injury by
childhood infections Metabolic pathways ot normal and
injured respiratory cells
ROIHL 19431 03 Regional mucociliary transport m ine
human lung
" ROIHL 20184 02 Oesensiti2ation of tracheal muscle to
isoproterenol (rats, rabbits)
ROIHL 20868-02 Regulation ol glycoprotein biosynthesis in
lung (swine) , . ^.
•* R23HL-2 11 50-02 Regulation ol airway mucous glands ana
ion transport (dogs, ascaris)
R23HL-2n9902 Sound transmission in lung (dog)
ROlHL-2 13 14-02 Respiratory tract secretion of ions, water
and mucus (human, dogs)
•• R23HL21369-02
bronchitis (rats)
Cellular and molecular aspects of
- Cortisoldependent alterations in
POlHL-19737-02 0001
respiratory physiology -
alveolar cells (rats)
POlHL-19737-02 0003
respiratory physiology
lung type II cells (rats)
ROlHL-19752-03 Phospholipid synthesis by fetal lung in
organ culture (rats)
ROlHL-20366-03 Protein turnover and ammo acid
transport by lung (rats)
ROlHL-20652-01 Sites of leakage in pulmonary edema
ROlHL-20773-02 Surfactant, pulmonary edema, and lung
mechanics (rabbits)
ROlHL-20783-02 Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
ROlHL-20868-02 Regulation of glycoprotein biosynthesis in
lung (swine)
ROlHL-21008-02
cultures (rats)
ROlHL-2 1009-02
culture (rats)
ROlHL-21140-01
Effect of pollutants on organotypic lung
Effects of air pollutants on lung cells in
Studies of pulmonay alveolar
macrophage function (rabbits)
ROlHL-21176-02 Phospholipid exchange proteins in lung
tissue (lambs)
R23HL-21251-01 Metabolism of neutral lipids in tne
pulmonary alveolus (rabbits)
ROlHL-2 1628-02 Biosynthesis of lung surfactant lipid
(rabbit)
ROlHL-22333-01
(rats)
ROlHL-22552-02
disease (sheep)
ROlHL-22723-01
Cellular basis of small airways function
Abnormal alveolar permeability and lung
I
The morphologic basis of airflow
obstruction (human)
R23HL-22895-01 Smoke inhalation -Biochemical and
cellular responses (rabbits, bacteria)
ROlHL-23969-01 Surfactant synthesis by type II cells in
vitro (rats)
II, UUBO,
Tracheal mucin synthesis in experimental
Biochemistry of lung proteoglycans
The airway mucosal barrier (guinea pigs)
RESPIRATORY SYSTEM PHARMACOLOGY
ROIHL 21612-02
(human, rabbits)
R01HL-22924-01
SEE ALSO RESPIRATORY DISORDERS CHEMOTHERAPY
POlHL-06285-18 0181 Cardiovascular-respiratory
physiology and biochemistry - Regulation of respiration-
Role of vagus nerve (dogs)
POlHL-06285-18 0188 Cardiovascular-respiratory
physiology and biochemistry - Physiology and pharmacology
in regulation of airways-hyperirritability (animals)
POlHL-06285-18 0189 Cardiovascular-respiratory
physiology and biochemistry - Mucociliary clearance (cats,
dogs)
POlHL-06285-18 0190 Cardiovascular-respiratory
physiology and biochemistry - Maximal (airway) flow
(human, dogs)
POlHL-06285-18 0209 Cardiovascular-respiratory
physiology and biochemistry - Metabolic studies of isolated
lung cells (human, animals)
POlHL-06664-17 0043 Cardiopulmonary function in
remediable vascular disease - Alveolar hypoxic
vasoconstriction -Control and clinical significance (dog,
human) , ,,, . ,
POlHL-08805-15 0045 Regulation of ventilation and
pulmonary circulation - Integrated description of
neurochemical respiratory control system
• POlHL-08805-15 0047 Regulation of ventilation and
pulmonary circulation - Extracranial metabolic control ot
ventilation (dogs, goats)
* POlHL-10342-13 0024 The integrated function ot
respiration and circulation - Cytochrome P450 and
physiological response to hypoxia (rats)
ROlHL-10622-12 Volumes and compliance of pulmonary
circulation (human, dogs)
ROlHL-10834-09 Fetal and neonatal pulmonary circulation
(sodts)
P50HL-14136-07 0001 Pulmonary SCOR -Airways
obstructive diseases ■ Experimental airway obstructive
disease (dogs)
«* P50HL-141 5307 0011 Johns Hopkins Lung Center-
Chronic diseases of airways - Allergy, airways reactivity
and asthma in human ragweed allergy
•* P50HL-141 53-07 0013 Johns Hopkins Lung Center-
Chronic diseases of airways - Pulmonary mechanics and
mediators of allergic reactions (guinea pigs, human)
•• P50HL-14 153-07 0014 Johns Hopkins Lung Center-
Chronic diseases of airways - Mediator release in asthma
(human)
P50HL-141 53-07 0017 Johns Hopkins Lung Center-
Chronic diseases of airways ■ Collateral ventilation and
pulmonary interdependence (pig, dog, human)
M P50HL-14187-07 Pulmonary SCOR Chemical mediators in
pulmonary vascular responses
** P50HL-14187-07 0012 Pulmonary SCOR -Chemical
mediators in pulmonary vascular responses - Vasoactive
mediators in pulmonary disease (human, animal)
P50HL-141 87-07 0014 Pulmonary SCOR -Chemical
mediators in pulmonary vascular responses ■ Metabolism
and actions of vasoactive peptides in lung (human,
mammals) i„..i;„.
P50HL-142 14-07 0025 Newborn lung center for hyalme
membrane disease - Pulmonary vascular permeability and
lung water -Hyaline membrane disease (sheep)
ROIHI 14262 07 liukocyl* proteaws and Iheii lung
targel^ (human, dogs, rabbilt)
ROIHI 142/1 0/ Physico chemical propertm ol litcMti
mucus (dogs, frogs)
ROIHI 14844 06 Mucoul glycoprotein in human respiratory
epithelium (also wheat)
POIHI 14985 0/ Adaptation to hypoxia . . , ,,
POIHI 14985 0/ 0004 Adaptation to hypoxia Control ol
breathmg in lespiialory lailure (human, dogs)
POIHL 14985 0/ 0009 Adaptation to hypoxia Inlluence
of chemosensitivity on control ol breathing during sleep
(human, dogs) „„i.i.
ROIHL 15002 0/ Biochemical pharmacology ol guanylale
cyclase in lung (cattle, rats)
P50HL 15092 07 0005 Immune and tibrolic response to
occupational environments Respiratory and immunologic
evaluation ol toluene diisocyanate exposure (human
ROIHL 1559305 Prolonged extracorporeal cardiopulmonary
support (rats, sheep, rabbits)
ROIHL 1565905 Dynamic isolation studies ol control ol
respiration (human)
ROIHL 16730 03 Physiology ol mucociliary transport irais.
frogs, rabbits)
ROIHL 1732204 Functional characteristics of smooth
muscle isolated from lung (animals)
POIHL 17382 05 0001 Chemical mediators ol acute
pulmonary disorders Chemical mediators and respiratory
mechanics in humans
POIHL 17382-05 0002 Chemical mediators of acute
pulmonary disorders Chemical mediators and respiratory
mechanics in guinea pigs
ROIHL 17768 04 Development ol collateral ventilation
(dogs, lish, horses)
•* ROIHL 18070 04 Regulation ol intrapulmonary airways
and vessels (human, animals)
ROlHL-18308-03 Comprehensive studies of mucociliary
transport (dogs)
** ROlHL-18606-04 Pathogenesis and measurement oi
pulmonary edema (human, rabbits, dogs)
ROlHL-18679-04 Synthetic protease inhibitors
** ROIHL 19115-02 Hormonal control of tracheobronchial
cyclic AMP (rats, guinea pigs)
P50HL-19153-02 0001 SCOR -Pulmonary edemas -Eitology,
pathogenesis Prostaglandins and the lung circulation
P5oV-%153-02 0002 SCOR-Pulmonary edemas-Eitology,
pathogenesis Lung fluid dynamics -Classical mediators
and then inhibitors (sheep)
P50HL-19153-02 0003 SCOR-Pulmonary edemas-Eitology,
pathogenesis - Possible inhibitors of mediator release and
pulmonary vascular response (sheep)
" P50HL-19156-02 0001 Pulmonary SCOR -Chronic diseases
of airways - Irritability of airways induced by epithelial
damage m healthy subjects (human)
•* P50HL-19156-02 0004 Pulmonary SCOR -Chronic diseases
of airways - Interactions between mast cells, mediators
and nerves in canine asthma
P50HL-19156-02 0005 Pulmonary SCOR-Chronic diseases
of airways - Vagal receptors in the airway-Epithelial iniury
and antigen (dog, cat, rabbit)
P50HL-19160-02 0001 Mucus abnormality in cystic
fibrosis - Regulation of respiratory secretions (rat, human)
P50HL-19160-02 0002 Mucus abnormality in cystic
fibrosis - Ultrastructure, cytochemistry of pulmonary
secretion (human, rat)
•* P50HL-191 70-02 0003 Harvard pulmonary SCOK-cnronic
diseases of the airways - Mechanisms of bronchial
reactivity to acute and chronic airway challenge (dog)
P50HL-19185-02 0003 Pulmonary SCOR -Neonatal
respiratory distress syndromes - Factors afiecting formation
and release of pulmonary surfactant in fetal lambs
P50HL-19 185-02 0004 Pulmonary SCOR -Neonatal
respiratory distress syndromes - Fluid and protein transport
in fetal and newborn lung (sheep, rabbits)
ROlHL-19225-02 0003 Types and mechanims of
pulmonary hypertension - Cardiopulmonary function in pigs
and rats
ROlHL-19431-03 Regional mucociliary transport in the
human lung
" ROlHL-19633-02 Pathogenesis and pharmacology ot lung
fibrosis (rats, rabbits)
*♦ ROlHL-19654-03 Biochemical-pharmacological evaluation
of lung cells (rabbits)
ROlHL-19700-03 Deposition of hygroscopic aerosols
(models) ^ . ,
ROlHL-19704-03 Aerosol therapy (models, dogs, human)
ROlHL-19715-02 Respiratory tract deposition of
hygroscopic aerosols (dogs, human)
ROlHL-19722-03 Aerosol growth in the respiratory system
(models)
ROlHL-19779-03 Biochemical basis of oxygen damage to
lung cells (guinea pigs, rats)
" ROlHL-20024-03 Therapeutic aerosols-Characteristics ana
retention (human, dogs)
** ROlHL-20087-02 Developmental processes in pulmonary
hypertension (rats)
ROlHL-20352-02 Defenses of lung cells against oxygen
toxicity (human, animals)
** ROlHL-20989-01 Pathophysiology of bronchial asthma
(sheep, dogs)
(contd)
•Excludes routine methodology OR covers only general projects which preclude
••Oiiented significantly to above subject.
indexmBatthespecificlevel.
M Grant has subproiects describing specific research aspects.
See Appendix lor investigators name and grant number.
RES
POlHL.20994-02 0008 Dynamics of neutrophil elastase in
the lung - Structure-function correlation in experimental
emphysema (humani dogs)
ROlHL-21076-02 Lung fluid, protein exchange after
hemorrhagic shock (sheep)
R01HL-21I26-02 Exercise-induced bronchospasm in
children
R23HL-21251-DI Metabolism of neutral lipids in the
pulmonary alveolus (rabbits)
ROlHL-21314-02 Respiratory tract secretion of ions, water
and mucus (human, dogs)
R23HL-21539-02 Mechanical properties of isolated small
bronchioles (rabbits)
** POlHL-21584-02 0005 Respiratory mechanics in normal
and abnormal states ■ Regulation and behavior of airv»ay
smooth muscle (human, animals)
ROlHL-2217702 Mechanisms of control of pulmonary
smooth muscle (dogs)
ROlHL-22333-01 Cellular basis of small airways function
(rats)
ROlHL-2264101 Ventilation, perfusion, and systemic
arterial reflexes (dogs)
ROIHL-22911-01 Mechanism of clearance of lung edema
fluid (dogs)
ROlHL-2398101 Acute alveolar injury (dogs)
RESPIRATORY SYSTEM PRESERVATION, LUNG
PRESERVATION
POlHL-17417-05 0006 Experimental lung transplantation
- Bronchial anastomotic problems and increases donor lung
availability (dog)
R01HL17944-D3 Studies in lung preservation (dogs)
ROlHL-18143-03 Surgery and pulmonary tissue alterations
(dogs, rats, human)
** NOlHR-62930-03 Lung cell resource facility
RESPIRATORY SYSTEM PROSTHESIS, PROSTHETIC
LUNG
ROlHL-1 1945-10 Synthesis of artificial lung and kidney
systems (sheep, mice, swine)
R01HL15668-06 Extracorporeal respiratory gas exchange -
A new approach (dogs)
R01HL16154-05 Membrane lung perfusion for acute
respiratory failure (sheep, baboons)
** ROlHL-16582-05 Artificial lungs (dogs)
P01HL19737-02 0010 Cellular and molecular aspects of
respiratory physiology ■ Effects of pulsatile flow and volume
on capillary exchanges (dogs, rats)
RESPIRATORY SYSTEM REFLEXES
SEE ALSO BRAIN, RESPIRATORY CENTER
SEE ALSO RESPIRATORY FUNCTION, HYPOVENTILATION
RESPIRATORY CENTER DYSFUNCTION
POlHL-0628518 0180 Cardiovascular-respiratory
physiology and biochemistry - Vagal C-fibers and their
influence on visceral and somatic function (animals)
P01HL0628518 0181 Cardiovascular-respiratory
physiology and biochemistry - Regulation of respiration -
Role of vagus nerve (dogs)
P01HL06285-I8 0188 Cardiovascular-respiratory
physiology and biochemistry - Physiology and pharmacology
in regulation of airways-hyperirritability (animals)
ROlHL-08789-11 Respiratory muscles and ventilatory
control in man (and dogs)
P50HL1415307 0013 Johns Hopkms Lung Center-
Chronic diseases of airways ■ Pulmonary mechanics and
mediators of allergic reactions (guinea pigs, human)
•* P50HL14214-07 0027 Newborn lung center for hyaline
membrane disease ■ Orallaryngeal chemoreceptors and
respiratory failure in newborns (human, sheep)
•• P50HL-14214.07 0029 Newborn lung center for hyaline
membrane disease - The diving reflex-Perinatal asphyxia,
pulmonary ischemia and HMD (sheep)
** P01HLI4580-07 0003 Program project in respiratory
mechanics - Chest wall mechanics and respiratory control
(human, dogs)
R01HL16430-05 Neural control of respiration (cats)
M P01HL1687805 Control of ventilation in health and
disease
P01HL16878-05 0001 Control of ventilation in health
and disease ■ Ability of asthmatics to detect added
resistive and elastic loads
POlHL-16878-05 0003 Control of ventilation in health
and disease - Brain stem respiratory neurons in response
mechanical/chemical loading (animal)
ROIHLI 7800-04 Pulmonary reflexes -Central pathways
(cats, dogs, rabbits)
R01HL-I8007-05 Neural mechanisms controling motor act
of breathing (cats, human)
P50HL-I9155-02 0001 Pathophysiology of pulmonary
edema - Pulmonary edema study unit (human, dog)
M P50HL19I56-02 Pulmonary SCOR-Chronic diseases of
airways
P50HL-191 56-02 0001 Pulmonary SCOR-Chronic diseases
of airways - Irritability of airways induced by epithelial
damage in healthy subjects (human)
" P50HL-19156-02 0004 Pulmonary SCOR-Chronic diseases
of airways - Interactions between mast cells, mediators
and nerves in canine asthma
*• P50HL-I9156-02 0005 Pulmonary SCOR-Chronic diseases
of airways - Vagal receptors in the airway-Epithelial injury
and antigen (dog, cat, rabbit)
488
P50HL-1917002 0006 Harvard pulmonary SCOR-Chronic
diseases of the airways ■ Mechanism of overdistension
(human, animal)
** P50HL-191 70-02 0008 Harvard pulmonary SCOR-Chronic
diseases of the airways - Multiple-transient artificial
coughing (dogs, human)
ROlHL-23601-01 Early hypoxia and development of
respiratory control
RESPIRATORY SYSTEM SURGERY
POlHL-06312 17 0053 Surgical cardiology Enzyme
pattern following cardiac surgery (human)
ROlHL-1691604 0011 The role of albumins in lung water
accumulation - Whole body distribution and exchange of
albumin (rabbits, human, monkeys)
POlHL-17417-05 0006 Experimental lung transplantation
■ Bronchial anastomotic problems and increases donor lung
availability (dog)
R01HL18143-03 Surgery and pulmonary tissue alterations
(dogs, rats, human)
RESPIRATORY SYSTEM SURGERY,
PNEUMONECTOMY
P50HL-1506I-07 0004 Response of lung to injury -
Biochemical abnormalities in connective tissues (rats)
ROlHL-18143-03 Surgery and pulmonary tissue alterations
(dogs, rats, human)
POlHL-19717-02 0004 Response of the lung to injury -
Regulatory and physical-chemical properties of lung lysyl
oxidase (animals)
** POlHL-19717-02 0028 Response of the lung to injury -
Compensatory growth of the lung following pneumonectomy
(rabbits)
RESPIRATORY SYSTEM TOXINS
SEE RESPIRATORY DISORDERS. RESPIRATORY SYSTEM
TOXINS
RESPIRATORY SYSTEM TRANSPLANTATION,
LUNG TRANSPLANTATION
SEE ALSO RESPIRATORY SYSTEM PRESERVATION, LUNG
PRESERVATION
** ROlHL-08696-15 0020 Orthotopic heart transplantation •
Complete cardiopulmonary transplantation (dogs)
** ROlHL-13987-04 Transplantation of the lung (dogs)
M^ P01HL17417-05 Experimental lung transplantation
POIHL- 174 17-05 0001 Experimental lung transplantation
- Mechanisms and mediators of lung allograft rejection
(dogs, mice)
POlHL-1741705 0003 Experimental lung transplantation
- Methods for detecting lung allograft rejection (dogs)
POlHL-17417-05 0004 Experimental lung transplantation
- Methods for suppressing lung allograft rejection (dogs,
mice)
POIHL- 174 1705 0005 Experimental lung transplantation
- Lung transplantation in bilateral emphysema (dogs)
" P01HL17417-05 0006 Experimental lung transplantation
- Bronchial anastomotic problems and increases donor lung
availability (dog)
ROlHL-17944-03 Studies in lung preservation (dogs)
ROlHL-18143-03 Surgery and pulmonary tissue alterations
(dogs, rats, human)
RESPIRATORY TUBERCULOSIS
SEE BACTERIAL DISEASES, ACTINOMYCETALES INFECTIONS
TUBERCULOSIS
RESPIRATORY VIRUSES
SEE VIRUSES, RESPIRATORY (GENERAL)
RESPIRATORY VISUALIZATION*
** POlHL-06370-17 0013 Cardiopulmonary and renal
pathology research center - Morphologic analysis of
vascular prosthesis (human, dogs)
P50HL-14136-07 0004 Pulmonary SCOR -Airways
obstructive diseases - Morphometric studies of developing
emphysema (human)
** P50HL-14136-07 0005 Pulmonary SCOR-Airways
obstructive diseases ■ Radiographic studies of airways
obstructive disease (human)
" P50HL-14136-07 9004 Pulmonary SCOR -Airways
obstructive diseases ■ Radiology core (human)
** P50HL-1418707 0008 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses ■ Pulmonary
thromboembolism (dogs, human)
POlHL-14580-07 0001 Program project in respiratory
mechanics • Micromechanics of the lung (dogs, rats)
P50HL15092-07 0013 Immune and fibrotic response to
occupational environments - Epidemiology core resource
ROlHL-22844-01 Phrenic nerve pacing-Noninvasive
diaphragm analysis (human, dogs)
RESPIRATORY VISUALIZATION,
BRONCHOGRAPHY*
•* P50HL14136-07 0005 Pulmonary SCOR-Airways
obstructive diseases ■ Radiographic studies of airways
obstructive disease (human)
P50HL14136-07 9004 Pulmonary SCOR-Airways
obstructive diseases ■ Radiology core (human)
" P50HL-I91 5602 0003 Pulmonary SCOR-Chronic diseases
of airways ■ Powdered tantalum to study airway morphology
and mucociliary clearance (human)
•Excludes routine methodology OR covers only general projects which preclude indexing
Onented significantly to above subject.
at the specific level.
M Grant has subprojects descnbing specific research aspects
See Appendix for investigator's name and grant number
RET
RESPIRATORY VISUALIZATION,
BRONCHOSCOPY*
R01HL13885-08 9002 Cystic fibrosis and pulmonary
disease - Computer core facility (human)
** R01HL13885-08 9003 Cystic fibrosis and pulmonary
disease - Fiberoptic bronchoscopy core facility (human,
dogs, sheep)
R01HL-20I92-02 Ciliary activity of the lung studied by
laser scattering
RESPIRATORY VISUALIZATION, LUNG
SCANNING*
M POlHL-04664-18 Cardiovascular and lung dynamics
POlHL-04664-18 0002 Cardiovascular and lung dynamics
• X-ray cross section imaging of organs (dogs)
POlHL-04664-18 0009 Cardiovascular and lung dynamics
- Biological signal and image processing techniques (dogs)
POlHL-04664-18 0010 Cardiovascular and lung dynamics
- Left ventricular dynamics (human)
P01HL04664-18 0016 Cardiovascular and lung dynamics
- Computerized roentgenographic determination of total
lung capacity
" ROlHL-1000913 Regional lung function in man
R01HL12833-09 Genetic and environmental influences on
lung disease (human)
R01HL13754-08 Postoperative thromboembolism in
surgical patients (human)
ROlHL-13824-06 Defense mechanisms in pathogenesis of
emphysema (human, dogs)
P50HL-14187-07 0008 Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses - Pulmonary
thromboembolism (dogs, human)
R01HL15607-06 Physiological control of splanchnic
circulation (dogs)
R01HL18606-04 Pathogenesis and measurement of
pulmonary edema (human, rabbits, dogs)
ROIHL- 18968-03 Computer technology for transaxial
tomography
M POlHL-19717-02 Response of the lung to injury
** POlHL-1971702 0021 Response of the lung to injury -
Gallium lung scans in fibrosing alveolitis (hamsters)
** POlHL-1971702 0039 Response of the lung to injury -
Lung scanning in alveolitis and asbestolic interstitial
pneumonia (human, animal)
** POlHL-19717-02 0043 Response of the lung to injury ■
Asbestosis as a model of usual interstitial pneumonia
(human)
" P01HL19717-02 0044 Response of the lung to injury -
Lung sound analysis (human)
POlHL-19717-02 0046 Response of the lung to injury -
Bioengineering section
ROlHL-21518-01 Improvement in regional ventilation-
perfusion resolution (human)
ROlHL-22852-01 Diagnostic techniques in venous
thromboembolism (human)
RESPONSE
SEE STIMULUS-RESPONSE (GENERAL)
REST
SEE HEALTH, PHYSICAL ACTIVITY, REST
RESTIM
SEE BLOOD AND RE SYSTEM, RE STIMULATING FACTORS
RESTRICTION ENOONUCLEASES
SEE NUCLEASES, ENOONUCLEASES (GENERAL)
RESUSCITATION, ARTIFICIAL RESPIRATION
SEE RESPIRATORY ASSIST AND OXYGEN ADMINISTRATION
ARTIFICIAL RESPIRATION
RESUSCITATION, HEART
SEE HEART RESUSCITATION
RETICULAR FORMATION
SEE BRAIN. RETICULAR FORMATION
RETICULOCYTES
SEE BLOOD CELLS, ERYTHROCYTES. RETICULOCYTES
RETICULOENDOTHELIAL STIMULATING FACTORS
SEE BLOOD AND RE SYSTEM, RE STIMULATING FACTORS
RETICULOENDOTHELIAL SYSTEM
SEE BLOOD AND RE SYSTEM, RETICULOENDOTHELIAL
SYSTEM (GENERAL)
RETICULOSPINAL TRACT
SEE NERVOUS SYSTEM CENTRAL, RETICULOSPINAL TRACT
RETINA
SEE EYE, RETINA
RETINA DETACHMENT
SEE EYE DISORDERS, RETINA AND CHOROID DISORDERS
RETINA DETACHMENT
RETINA DISORDERS
SEE EYE DISORDERS, RETINA AND CHOROID DISORDERS
(GENERAL)
RETINAL, BACTERIAL
SEE PIGMENTS, BACTERIAL. BACTERIORHODOPSINRETINAL
RETINAL ARTERIES
SEE EYE CIRCULATION, RETINAL ARTERIES
(contd)
RET
RETINAL-CHOROIDAl CIRCULATION
Sff tY( CIRCUIATION. RUINAl CHOROIDAL CIRCULATION
RETINAL CIRCULATORY DISORDERS
Sft m CIRCULATORY DISORDtRS, RHINM CIRCULATORY
DISORDERS
RETINAL HEMORRHAGE
Sff tYf CIRCULATORY DISORDERS. RETINAL (INCLUDING
VITREOUS) HEMORRHAGE
RETINOGRAPHY
SEE EYE DISORDERS DIAGNOSIS. RETINOGRAPHY*
RETINOIC ACID
SEE VIIAMIN A ACID
RETINOL
SEE VIIAMIN A
RETRANSPLANTATION
SEE TISSUE COMPATIBILITY TRANSPLANT,
RETRANSPLANTATION
RETRIEVAL, INFORMATION
SEE INFORMATION SYSTEMS. INFORMATION RETRIEVAL
RETROLENTAL FIBROPLASIA
SEE EYE DISORDERS. RETROLENTAL FIBROPLASIA
REVASCULARIZATION HEART
SEE HEART REVASCULARIZATION
REVASCULARIZATION KIDNEY
SEE KIDNEY SURGERY, KIDNEY REVASCULARIZATION
REVASCULARIZATION MYOCARDIAL
SEE HEART REVASCUURIZATION
REVASCULARIZATION NON-SURGICAL
SEE CAROIOVASCUl^kR SYSTEM, BLOOD SUPPLY.
REVASCULARIZATION NONSURGICAL
REVASCULARIZATION SURGICAL
SEE CAROIOVASCUUR SURGERY. REVASCULARIZATION
SURGICAL
REWARDS AND NON-REWARDS
SEE PSYCHOLOGY, MOTIVATION, REWARDS AND NON-
REWARDS
RH ANTIBODIES
SEE BLOOD GROUPS ISOANTIBODIES. RH ANTIBODIES
RH FACTORS
SEE BLOOD GROUPS, RH SYSTEM
RH SYSTEM
SEE BLOOD GROUPS. RH SYSTEM
RHEOIOGY AIR
SEE PHYSICAL PROPERTIES. RHEOLOGY (NOT INCL. BLOOD)
RHEOLOGY BODY FLUIDS OTHER THAN BLOOD
SEE PHYSICAL PROPERTIES, RHEOLOGY (NOT INCL. BLOOD)
RHEOLOGY, BLOOD
SEE BLOOD RHEOLOGY
RHEOLOGY GASES
SEE PHYSICAL PROPERTIES. RHEOLOGY (NOT INCL. BLOOD)
RHEOLOGY LIQUIDS
SEE BLOOD AND RE SYSTEM. LYMPH FLOW
SEE CARDIOVASCULAR FUNCTION. BLOOD FLOW
SEE PHYSICAL PROPERTIES. FLUID FLOW
RHEOLOGY (NOT INCL. BLOOD)
SEE PHYSICAL PROPERTIES. RHEOLOGY (NOT INCL BLOOD)
RHEOLOGY PLASTIC FLOW OF SOLIDS
SEE PHYSICAL PROPERTIES. RHEOLOGY (NOT INCL. BLOOD)
RHEOLOGY SKIN
SEE PHYSICAL PROPERTIES. RHEOLOGY (NOT INCL. BLOOD)
RHESUS MONKEYS
SEE MAMMALS. PRIMATES, MONKEYS AND APES
(ANTHROPOIDS, NON-HUMAN), OLD WORLD MONKEYS,
MACACA SP., MACACA MULATTA*
RHEUMATIC DISORDERS
SEE CONNECTIVE TISSUE DISORDERS, RHEUMATIC
DISORDERS
RHEUMATIC FEVER
SEE BACTERIAL DISEASES, STREPTOCOCCAL INFECTIONS,
RHEUMATIC FEVER
RHEUMATIC HEART DISEASE
SEE HEART DISORDERS, RHEUMATIC HEART DISEASE
RHEUMATOID ARTHRITIS
SEE SKELETAL DISORDERS, ARTHRITIS, RHEUMATOID
RHINITIS
SEE NASAL DISORDERS, RHINITIS
RHODOPSIN, BACTERIAL
SEE PIGMENTS, BACTERIAL, BACTERIORHODOPSIN-RETINAL
"^Excludes routine methodology OR covers only general proiecls which preclude
"Oriented signiticantly to above subject
489
RHODOTOXINS
Sfl lOXICOlOGY, PIANI POISONS, GRAYANOTOKINS
RIBOFLAVIN
Sff flAVIN NUCIFOSIDFS. RIBOIIAVIN
RIBONUCLEASE
SIf NUClfASlS, RIBONUCLEASE
RIBONUCLEIC ACID(S)
Sff NUCLEIC ACIDS, RNA
RIBONUCLEIC ACID POLYMERASE
SEE NUCLEOTIDYLTRANSFERASES. RNA
NUCLEOTIDYLTRANSFERASES
RIBONUCLEIC ACIDS REPLICATION
SEE NUCLEIC ACIDS SYNTHESIS. RNA
RIBONUCLEOPROTEINS
SEE NUCLEOPROTEINS. RIBONUCLEOPROTEINS
RIBONUCLEOSIDE TRIPHOSPHATE RNA
NUCLEOTIDYLTRANSFERASE
SEE NUCLEOTIDYLTRANSFERASES. RNA
NUCLEOTIDYLTRANSFERASES
5'-RIBONUCLEOTIDE PHOSPHOHYDROIASES
SEE PHOSPHOMONOESTERASES. 5' NUCLEOTIDASE
RIBOPOLYNUCLEOTIDES
SEE NUCLEOTIDES. RIBOPOLYNUCLEOTIDES
RIBOSOMAL RNA
SEE NUCLEIC ACIDS. RRNA
RIBOSOMES
SEE CELL COMPONENTS. RIBOSOMES
RIBS
SEE SKELETAL SYSTEM. RIBS
RILEY DAY SYNDROME
SEE CONGENITAL ABNORMALITIES. NEUROLOGICAL,
DYSAUTONOMIA FAMILIAL
RILEY VIRUS
SEE VIRUSES, TOGAVIRUSES, RILEY VIRUS
RISK, DISEASE PRONENESS
SEE DISEASE PRONENESSRISK
RISTOCETIN A
SEE ANTIBIOTICS, RISTOCETIN A
RNA
SEE NUCLEIC ACIDS, RNA
RNA BIOSYNTHESIS
SEE NUCLEIC ACIDS SYNTHESIS, RNA
RNA METHYLATED
SEE NUCLEIC ACIDS, METHYLATED RNA
RNA NUCLEOTIDYLTRANSFERASE
SEE NUCLEOTIDYLTRANSFERASES, RNA
NUCLEOTIDYLTRANSFERASES
RNA POLYMERASE
SEE NUCLEOTIDYLTRANSFERASES, RNA
NUCLEOTIDYLTRANSFERASES
RNA REPLICATION
SEE NUCLEIC ACIDS SYNTHESIS, RNA
RNA VIRAL
SEE NUCLEIC ACIDS, RNA VIRAL
RNA VIRUSES (GENERAL)
SEE VIRUSES, RNA VIRUSES (GENERAL)
RNCI-2 VIRUSES
SEE VIRUSES, ONCORNA, LEUKEMIA MOUSE RAUSCHER
RODS, GRAM-NEGATIVE
SEE BACTERIA, GRAM-NEGATIVE*
ROENTGEN VIDEODENSITOMETRY
SEE CARDIOVASCULAR VISUALIZATION, ROENTGEN
VIDEODENSITOMETRY*
ROSETTE TEST
SEE IMMUNOLOGICAL TESTS AND IMMUNOASSAY, IMMUNE
ADHERENCE REACTION
ROUTE OF ADMINISTRATION
SEE DOSAGE AND ROUTE, ROUTE OF ADMINISTRATION
ROUTE OF NUTRIENT ADMINISTRATION
SEE NUTRITION, DIET SCHEDULE AND ROUTE
RRNA
SEE NUCLEIC ACIDS, RRNA
RUBBER
SEE PLASTICS, RUBBER
RUBIDIUM
SEE METALS, ALKALI METALS, RUBIDIUM
RUBIDIUM RADIOISOTOPES (81,86)
SEE RADIOISOTOPES, RUBIDIUM
RUBIDOMYCIN
Ml ANMRIOTICS, OAUNOMYCIN
RUMEN BACTERIA
Slf BACIIHIA, (NiERIC, RUMEN BACTERIA-
RURAL AREAS
SK SOCIOENVIRONMENI, RURAL ARIAS
RUTHENIUM
Sff MfFAIS, HfAVY MFIAIS. RUTHENIUM
RYANIA ALKALOIDS
SEE ALKALOIDS, RYANIA
S-A NODE
SEE HEART, CONDUCTION SYSTEM. SINO AIRIAI NODE
SAFETY OF DIAGNOSTIC PROCEDURES
SEE DIAGNOSTIC QUALITY STANDARDS. DIAGNOSTIC
PROCEDURES SAFETY
SAFETY OF MEDICAL EQUIPMENT
SEE BIOMEDICAL ENGINEERING. MEDICAL EQUIPMENT
SAFETY
SALBUTAMOl
SEE PHENYLALKYLAMINES. SALBUTAMOl
SALICYLATES
SEE PHENYLCARBOXYUTES, SALICYUTES
SALICYLAZOSULFAPYRIDINE
SEE SULFANILAMIDES, SALICYLAZOSULFAPYRIDINE
SALINE SOLUTIONS
ROIHL 10622-12 Volumes and compliance of pulmonary
circulation (human, dogs) K„,i.n.
P50HL U214 07 0027 Newborn lung center for hyaline
membrane disease Oral laryngeal chemorecepto.s and
respiratory failure in nev»borns (human, sheep)
SALIVA
SEE ORALPHARYNGEAL, SALIVA
SALIVARY GLANDS
SEE ORALPHARYNGEAL. SALIVARY GLANDS
SALIVARY GLAND VIRUSES
SEE VIRUSES. HERPESVIRUSES. CYTOMEGALOVIRUSES
SALIVATION
SEE ORALPHARYNGEAL. SALIVATION
SALT BACTERIA
SEE BACTERIA. HALOBACTERIACEAE*
SALT-FREE DIET
SEE NUTRITION, DIET THERAPEUTIC, SALT RESTRICTED
SALT GLAND
SEE BODY FLUID BALANCE, IONIC. SALT GUNO
SALT INTAKE (APPETITE)
SEE NUTRIENT INTAKE ACTIVITY. SALT INTAKE
SALT RESTRICTED DIET
SEE NUTRITION. DIET THERAPEUTIC. SALT RESTRICTED
SALTS IN THE DIET
SEE NUTRITION. DIETARY CONSTITUENTS. DIETARY SALTS
SALURESIS
SEE KIDNEY FUNCTION. SALURESIS
SAMALDHI
SEE PSYCHIC ACTIVITY LEVEL, TROPHOTROPIC STATE.
MEDITATION
SAMPLING
SEE AIR SAMPLING-MONITORING
SANGUINUS
SEE MAMMALS. PRIMATES. MONKEYS AND APES
(ANTHROPOIDS. NON-HUMAN). NEW WORLD MONKEYS
(PLATYRHINES)*
SAPONINS (TERPENE)
SEE TERRENES SAPONINS
SARALASIN
SEE PEPTIDES. OLIGOPEPTIDES. SARALASIN
SARCOIDOSIS
SEE NEOPLASMS RELATED INTEREST, SARCOIDOSIS
SARCOLEMMA
SEE MUSCLES. SARCOLEMMA
SARCOMERES
SEE MUSCLE CELLS. SARCOMERES
SARCOPLASMIC RETICULUM
SEE MUSCLE CELLS. SARCOPLASMIC RETICULUM
SARCOSINE
SEE AMINO ACIDS. SARCOSINE
SARCOSOMES
SEE MUSCLE CELLS. SARCOSOMES
(contd)
indexing at the specific level.
M Grant has subprolects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
SAT
SATURATED FATS
SEE LIPIDS. FATS. SATURATED FATS
SATURATED FATTY ACIDS
SEE FATTY ACIDS, SATURATED FATTY ACIDS
SAXITOXIN
SEE TOXICOLOGY. PROTOZOAL TOXINS, SAXITOXIN
SCANDINAVIAN COUNTRIES
SEE GEOGRAPHICAL SITES. EUROPE. SCANDINAVIAN
COUNTRIES
SCANNING (BODY, TISSUES, ORGANS)
SEE RADIOGRAPHY, SCANNING (GENERAL)*
SCANNING, CAT (EMI) (ACTASCAN)
SEE RADIOGRAPHY, SCANNING. CAT*
SCANNING, RADIONUCLIDE (RADIOISOTOPE)
SEE RAOIOAUTOGRAPHY. RADIONUCLIDE SCANNING*
SCANNING ELECTRON MICROSCOPY
SEE OPTICS. MICROSCOPY. ELECTRON SCANNING*
SCANNING-PRODUCED MOTION IMAGES
SEE RADIOGRAPHY. SCANNING, DSR
SCARS
SEE INJURIES. SCARS
SCH-13949W
SEE PHENYULKYUMINES. SALBUTAMOL
SCHEDULE, DOSAGE
SEE DOSAGE AND ROUTE. DOSAGE
SCHISTOSOMIASIS
SEE PARASITIC DISEASES, HELMINTH INFECTIONS
SCHISTOSOMIASIS
SCHOOLS
SEE EDUCATION. SCHOOLS
SCINTILLATION CAMERAS
SEE RADIOASSAY, SCINTILLATION CAMERAS*
SCINTILLATION COUNTERS
SEE RADIOASSAY. SCINTILUTION COUNTERS*
SCINTILLATION SCANNING
SEE RAOIOAUTOGRAPHY, RADIONUCLIDE SCANNING*
SCINTISCANNING
SEE RAOIOAUTOGRAPHY, RADIONUCLIDE SCANNING*
SCLERODERMA
SEE CONNECTIVE TISSUE DISORDERS. SCLERODERMA
SCLEROPROTEINS
SEE ALBUMINOIDS
SCLEROSIS (ARTERIAL)
SEE CARDIOVASCUUR DISORDERS. ARTERIOSCLEROSIS
SCLEROSIS DISSEMINATED(MULTIPLE SCLEROSIS)
SEE NERVOUS DISORDERS. MYELINOPATHIES. MULTIPLE
SCLEROSIS
SCLEROSIS PROGRESSIVE SYSTEMIC
SEE CONNECTIVE TISSUE DISORDERS. SCLERODERMA
SCOLIOSIS
SEE SKELETAL DISORDERS. SPINAL CURVATURES. SCOLIOSIS
SCREENING
SEE DIAGNOSTIC SERVICES, MASS SCREENING
SEE DRUGS SCREENING
SCREENING, TOXICOLOGICAL
SEE TOXICOLOGY, TOXICANT SCREENING
SCURVY
SEE NUTRITIONAL ABNORMALITIES, HYPOVITAMINOSIS C
SEALASE
SEE NUCLEIC ACIDS REPAIR. DNA REPAIR (ENZYME)
SEASONS, SEASONAL VARIATION
SEE ENVIRONMENT, CLIMATE, SEASONS
SECONDARY EDUCATION
SEE EDUCATION, SCHOOLS, SECONDARY
SECONDARY INFECTIONS
SEE COMMUNICABLE DISEASES, INFECTIONS, SECONDARY
SECRETIN
SEE GASTROINTESTINAL HORMONES. SECRETIN
SECRETION OF CELL Vt/ASTES
SEE BIOLOGICAL TRANSPORT, SECRETORY MECHANISMS
EXCRETION
SECRETORY IMMUNOGLOBULIN A
SEE IMMUNOLOGY. SECRETORY (ANTIBODY) (FACTOR)
SYSTEM
SECRETORY MECHANISMS
SEE BIOLOGICAL TRANSPORT. SECRETORY MECHANISMS
•SlV"''^'"^ methodolop OR covers only gene.al prelects which preclude indexing at the specific level
Urieitted significantly to above subiect.
490
SECRETORY (ANTIBODY) (FACTOR) SYSTEM
SEE IMMUNOLOGY, SECRETORY (ANTIBODY) (FACTOR)
SYSTEM
SECTIONING
SEE TISSUE AND CELL PREPARATION. SECTIONING
SEDATIVES
SEE PSYCHOPHARMACOLOGICAL AGENTS, HYPNOTICS AND
SEDATIVES
SELENIUM (COMPOUNDS)
SEE METALS. METALLOIDS. SELENIUM
SELENOMETHIONINE
SEE SULFUR AMINO ACIDS, METHIONINE, SELENOMETHIONINE
SELF-CONCEPT
SEE PSYCHOLOGY, PERSONALITY DEVELOPMENT, SELF-
CONCEPT
SELF MEDICATION
SEE DRUGS. CHEMOTHERAPY. SELF MEDICATION
SELF REGULATION (CONTROL) OF AUTONOMIC
(VISCERAL) RESPONSES
SEE PSYCHOLOGY. CONDITIONING, AUTOGENIC AND INTERNAL
CONTROL
SENECIO ALKALOIDS
SEE ALKALOIDS. SENECIO
SENILE DEMENTIA (PSYCHOSIS)
SEE BRAIN DISORDERS. CEREBRAL ATROPHY DIFFUSE
SENILE DEMENTIA
SENIOR CITIZENS
SEE AGE (HUMAN). ADULT. OLD AGE (65 TO 99 YRS)
SENSE ORGANS
ROlHL-1999502 Sensory transduction In cardiac
mechanoreceptors (cats, frogs, tats)
SENSE ORGANS, CHEMORECEPTORS
SEE ALSO NERVOUS SYSTEM. PARAGANGLIA
ROIHL 02888-22 Interrelationships of circulation and
respiration (opossum, cats)
R01HL-05883-18 0001 Reflex control of resistance and
capacitance vessels - Naturally occurring vasoactive
substances and the vascular neuroeffectors (dog)
ROlHL-06143-18 Response of the totally denervated heart
to exercise (dogs)
POlHL-06285-18 0180 Cardiovascular-respiratory
physiology and biochemistry - Vagal C-fibers and their
influence on visceral and somatic function (animals)
** POlHL-06285-18 0182 Cardiovascular-respiratory
physiology and biochemistry - Structure and function of
vascular chemoreceptors (cats, rats)
R01HL-07723-15 Reflex control of vascular capacitance in
shock
POlHL-07896-15 0014 Environmental biomedical research
program - Mechanisms of respiration and circulation
(human, dogs)
R01HL-08659-14 Myocardial performance and metabolism
in the newborn (sheep)
P01HL-08682-15 0038 Regulation of the cardiovascular
system - Control of pulmonary circulation (dogs)
P01HL-08805-15 0006 Regulation of ventilation and
pulmonary circulation - Adaptation of lungfish-Estivation
** POlHL-08805-15 0039 Regulation of ventilation and
pulmonary circulation - Carotid body (cats)
POlHL-08805-15 0044 Regulation of ventilation and
pulmonary circulation ■ Neurochemical interactions in
respiratory control (human, dogs, goats)
POlHL-0880515 0045 Regulation of ventilation and
pulmonary circulation - Integrated description of
neurochemical respiratory control system
** POlHL-08805-15 0046 Regulation of ventilation and
pulmonary circulation - Sites and modes of interaction of
peripheral and central chemoreceptors
POlHL-08805-15 0047 Regulation of ventilation and
pulmonary circulation - Extracranial metabolic control of
ventilation (dogs, goats)
** POlHL-08899-14 0019 Tolerance to respiratory gases in
health and disease ■ High oxygen pressure upon carotid
chemoreceptor (cats)
POlHL-08899-14 0030 Tolerance to respiratory gases in
health and disease ■ Dynamic characteristics of respiratory
control components (human, cats)
'* POlHL-10342-13 0011 The integrated function of
respiration and circulation - Control of respiration 1 -
Peripheral chemoreceptor studies (cats)
POlHL-10342-13 0019 The integrated function of
respiration and circulation - Cerebral circulation and
metabolism (dogs)
POlHL-10342 13 0024 The integrated function of
respiration and circulation Cytochrome P450 and
physiological response to hypoxia (rats)
* POlHL-10342-13 0026 The integrated function of
respiration and circulation - Control of respiration-
Characterization of the aortic body (cats)
POIHL 10436-13 0014 A multidisciplinary study of
congenital heart disease - Cardiovascular pharmacology
(dog)
SEN
POlHL-11678-11 0009 Cardiovascular dynamics and their
control - Control of respiration (cat. human)
ROlHL-11907-08 Mechanisms of physiological responses
to exercise (human, dogs)
ROlHL-12564-09
(human, dog)
ROIHL 13134-07
(cats)
ROlHL-13233-08
(human)
ROlHL-13841-16
Control of respiration and blood gases
Mechanism of chemoreceptor discharge
Cardiorespiratory control in exercise
Respiration during altitude
acclimatization (goats, dogs. rats, rabbits)
ROlHL-13888-15 Regulation of respiration
P50HL-14214-07 0027 Newborn lung center for hyaline
membrane disease Oral-laryngeal chemoreceptors and
respiratory failure in newborns (human, sheep)
POlHL-14388-07 0155 Regulation of the circulation in
pathological states - Cardiopulmonary afferent activity.
carotid chemo-baroreceptor reflexes
POIHL-14388-07 0183 Regulation of the circulation in
pathological states - Vasopressin in cardiovascular
regulation (dogs, rats)
POlHL-14388-07 0185
pathological states ■
rabbits, dogs)
POlHL-14388-07 0204
pathological states
Regulation of the circulation in
Reflex control of venous tone (human.
Hypoxia
- Control of
Ventilatory
Regulation of the circulation in
Reflex control of vascular resistance
in spontaneously hypertensive rats
POlHL-14388-07 0208 Regulation of the circulation in
pathological states - Baroreceptor reflex function in normal
and hypertensive man
ROlHL-14693-07 Survival value of physiological responses
to hypoxia (dogs)
R01HLI4870-06 Dynamics of oxygen and carbon dioxide
regulation (animals)
ROlHL-14967-06 Chemoreceptor function in dynamic
ventilatory control (human, dogs)
POlHL-14985-07 0003 Adaptation to hypoxia
and oxygen transport (human, dogs)
POlHL-14985-07 0004 Adaptation to hypoxia
breathing in respiratory failure (human, dogs)
■* POlHL-14985-07 0008 Adaptation to hypoxia
drive and exercise capacity (human, dogs)
■* POlHL-14985-07 0009 Adaptation to hypoxia - Influence
of chemosensitivity on control of breathing during sleep
(human, dogs)
ROIHL- 15307-06 Central nervous control of renin and
blood pressure (dogs)
ROIHL 15430-05 Cardiopulmonary adaptation of newborns
to altitude (human)
ROlHL-15659-05 Dynamic isolation studies of control of
respiration (human)
ROlHL-16022-05 Determinants of the ventilatory response
to hypoxia (goats, cats)
ROlHL-16066-05 Studies on neurogenic control of the
circulation (human, dogs)
ROlHL-16430-05 Neural control of respiration (cats)
ROlHL-16511-04 Sympathetic afferent activity of cardiac
origin (dogs, monkeys)
I P01HL-16910-05 Regulation of the peripheral circulation
• POlHL-16910-05 0005 Regulation of the peripheral
circulation - Control of circulation by baroreceptor and
chemoreceptor reflexes (dog. monkey)
P50HL-1 7667-04 0031 Study of ischemic heart disease -
Pathophysiology in ischemic heart disease (dog, cat, rabbit,
monkey)
ROlHL-17689-06 Neurophysiologic studies of respiratory
control (cats)
ROlHL-17711-05 Mechanism of hypoxic regulation of lung
circulation (rats, cats, guinea pigs)
POlHL-17731-04 0010 Physiological basis of pulmonary
disease - Gas exchange kinetics (dogs)
POlHL-17871-04 0009 Kidney, sodium, cardiac output,
arterioles and hypertension - Kidney, sodium, cardiac
output, arterioles and hypertension
ROIHL- 17903-03 Regional circulatory responses to hypoxia
(rats, cats, rabbits)
ROlHL-18630-03 Pulmonary hemodynamics in atelectasis
and hypoxia (dogs)
POlHL-19737-02 0005 Cellular and molecular aspects of
respiratory physiology - Interaction of respiratory exchanges
and blood gas parameters (human, animals)
POlHL-19737-02 0011 Cellular and molecular aspects of
respiratory physiology - Chemical and metabolic factors on
peripheral chemoreceptor activity (cats)
ROlHL-20568-03
(rats)
ROlHL-20574-03
activity (cats)
ROIHL 21988-01
chemotaxis
ROlHL-22296-01
ROlHL-22594-01
failure (dogs)
ROlHL-22641-01
arterial reflexes (dogs)
R23HL-22669-01
afferents (dogs)
ROlHL-22715-01
reflexes (dogs))
ROlHL-22928-01
(sheep)
Respiration during prolonged hypercapnia
Brain stem integration of chemoreceptor
Biochemistry of human platelet
M Grant has subprojects describing specific research aspects.
See Appendix tor investigators name and grant number.
Autonomic mechanisms in man
Reflex control of the circulation in heart
Ventilation, perfusion, and systemic
logs)
Cardiovascular effects from visceral
Neural integration of the cardiovascular
Systematic study of bronchial circulation
(contd)
SEN
SENSE ORGANS, MECHANORECEPTORS
SEE *IS0 MUSCLE FUNCTION. MUSCll SIR! ICH
(RECEPTORS)
SEE *LSO RESPIRATORY SYSTEM. PULMONARY STRETCH
RECEPTORS
SEE ALSO SENSE ORGANS. OSMORECEPTORS
SEE ALSO SINSf ORC.ANS, PRESSORECEPTORS
SEE ALSO SENSORY n RCtPIUAL PROCESSES,
PROPRIOCEPTION
R01HL0S883 18 0001 Reflex control ol tesist»nce and
c»p«cit«nce vessels Naturally occurring vasoactrve
sul)stances and the vascular neuroedectors (dog)
ROIHL 06143 18 Response ot the totally denervated heart
to exercise (dogs)
•• P01HL08682 IS 0027 Regulation ol the cardiovascular
system Cardiac mechanoreceptors Rellex regulation of
renal function (dogs)
ROIHL 11907 08 Mechanisms of physiological responses
to exercise (human, dogs)
•* R01HL1651104 Sympathetic aHerent activity of cardiac
origin (dogs, monkeys)
ROIHL 1771504 Respiratory muscle afferents in
respiratory control (cats)
ROIHL 18024 03 Regional myocardial flow and function
relationships (dogs)
** ROIHL 1904803 Structure of baioreceptots in
hypertension (rats)
R01HL19256 03 Arterial baroreceplors in cardiovascular
control (dogs)
•* ROIHL 19995-02 Sensory transduction in cardiac
mechanoreceptors (cats, frogs, rats)
ROIHL 2086401 Postnatal maturation of cardiovascular
regulatory system (minipig)
•* R23HL-21042-01 Cardiopulmonary reflexes and their
anatomical basis (dogs)
** R01HL2115802 Cardiac receptors with vagal C-tiber
afferents (cats)
ROlHL-21893-01 Blood volume distribution in hypertension
(human) k ^
** ROIHL 2259401 Reflex control ot the circulation in heart
failure (dogs)
SENSE ORGANS, OSMORECEPTORS
SEE ALSO PITUITARY GLAND. NEUROHYPOPHYSIS
P01HL1167811 0027 Cardiovascular dynamics and their
control • Vasopressin and thirst in control of body fluid
volumes and osmolality (dogs)
SENSE ORGANS, PRESSORECEPTORS
SEE ALSO CEREBROVASCULAR SYSTEM, CAROTID SINUS
ROlHL-0588318 0004 Reflex control of resistance and
capacitance vessels - Lett ventricular receptors v»ith
nonmedullated vagal afferents (cats)
R01HL05883-18 0005 Reflex control of resistance and
capacitance vessels ■ Differential blockade of medullated
and nonmedullated vagal afferents in the cat
R01HL05883-18 0006 Reflex control of resistance and
capacitance vessels - Cardiopulmonary vagal afferents in
the conscious dog
ROlHL-0614318 Response of the totally denervated heart
to exercise (dogs)
P01HL06285-18 0180 Cardiovascular-respiratory
physiology and biochemistry - Vagal Cfibers and their
influence on visceral and somatic function (animals)
" P01HL0683517 0044 Cardiovascular disease -
Baroreceplors in control of blood pressure during sleep
(dogs)
ROlHL-07723-15 Reflex control of vascular capacitance in
shock
POlHL-08682-15 0021 Regulation of the cardiovascular
system - Hypoglycemia in pathogenesis of shock (dog)
ROlHL-09154-14 Central control of distribution of organ
blood flow (monkeys)
POlHL-10342-13 0019 The integrated function of
respiration and circulation ■ Cerebral circulation and
metabolism (dogs)
POlHL-10436-13 0014 A multidisciphnaiy study ot
congenital heart disease - Cardiovascular pharmacology
Wog' , ...
P01HL10436-13 0015 A multidisciplinary study ol
congenital heart disease - Fetal and neonatal
cardiovascular physiology (sheep)
R01HL1095M1 Neural control of the heart (dogs, rats)
P01HL11678-11 0001 Cardiovascular dynamics and their
control - Body fluid volumes in the genesis of hypertension
(rats, dogs)
POlHL-1 1678-11 0027 Cardiovascular dynamics and their
control - Vasopressin and thirst in control of body fluid
volumes and osmolality (dogs)
POlHL-11678-11 0040 Cardiovascular dynamics and their
control - Control of plasma potassium concentration (dogs)
** POlHL-1167811 0069 Cardiovascular dynamics and their
control - Nervous control of the cirulation (dogs)
ROlHL-12415-10 Evaluation of left ventricular function
(dogs, rabbits)
** P01HL-13108-09 0021 Clinical heart transplantation -
Autonomic reflex regulation of ventricular function (human)
** POlHL-13108-09 0022 Clinical heart transplantation -
Studies on cardiac receptors (human)
ROlHL-13187-09 Central neural control of cardiovascular
function (cats)
R01HL13427-09 Neural control of blood volume (monkeys.
dogs)
49t
ROIHL 13623 08 Atrial receptors (dogs)
P50H1 1415908 0018 Speculued center ol research in
hypertension Sympathetic nervous system in hypertension
ROIHL 14306 07 Quantification of arterial pressure control
• POIHI 14388 0/ 0155 Regulation of the circulation in
pathological states Cardiopulmonary afferent activity.
carotid chemo baroreceptor reflexes
POIHL 1438807 0179 Regulation of the circulation in
pathological states Cultured muscle calls and their cross
innervation in vitro (rats, sheep)
POIHI 1438807 0180 Regulation ot the circulation in
pathological states Regulation ot cerebral blood flow
(dogs, monkeys)
POIHL 1438807 0184 Regulation ot the circulation in
pathological states Vestibular reflexes in control ol
circulation (human)
POIHL 1438807 0185 Regulation of the circulation in
pathological states Reflex control of venous tone (human.
rabbits, dogs) , , „ i„
POIHL 14388 07 0195 Regulation of the circulation in
pathological states General review of potential
pathophysiologic factors in spontaneous hypertension
POIHL 14388 07 0204 Regulation of the circulation in
pathological slates Reflex control of vascular resistance
in spontaneously hypertensive rats
*• POIHL 1438807 0208 Regulation of the circulation m
pathological states Baroreceptor reflex function m normal
and hypertensive man
P01HL14388-07 0209 Regulation of the circulation in
pathological states Neural regulation of vascular
resistance in human hypertension
P01HL14388-07 0229 Regulation of the circulation in
pathological states Mechanism of postural hypotension
(human) .
•* ROIHL 14529-07 Systems analysis of baroreflex (dogs)
ROIHL- 154 16-06 Cardiovascular control in normal and
disease states (dogs, baboons)
*• R01HL1569406 Pulmonary factors in circulatory
regulation
•* ROlHL-165 11-04 Sympathetic afferent activity of cardiac
origin (dogs, monkeys)
ROIHL 16648 16 Integrated control of cardiovascular
activity (cats)
R01HL1665706 Innervation of coronary arteries and heart
M P01HL1591005 Regulation of the peripheral circulation
" POlHL-169 10-05 0005 Regulation of the peripheral
circulation ■ Control of circulation by baroreceptor and
chemoreceptor reflexes (dog. monkey)
" P01HL1691005 0006 Regulation of the peripheral
circulation - Regulation of blood flow distribution (baboons,
dogs) , I
POlHL-1691005 0007 Regulation of the peripheral
circulation ■ CNS-Behavioral influences on circulation
(baboons) .
P01HL16910-05 0008 Regulation of the peripheral
circulation Circulation to bone (dogs, baboons)
ROlHL-17628-03 Pulsatile pressure-flow dynamics (dogs)
ROlHL-17903-03 Regional circulatory responses to hypoxia
(rats, cats, rabbits) , ,. ,
R01HL17970-04 Vascular effects of inhibitory behavioral
adaptations (dogs)
ROlHL-18024-03 Regional myocardial flow and function
relationships (dogs) , ^ „^,
P01HL18575-03 0006 Mechanisms of vascular changes
in hypertension ■ Evaluation of arterial compliance in
hypertension (human, pigs)
POlHL-18974-03 0001 Experimental neurogenic
hypertension program - Central neural systems regulating
arterial pressure (rabbits)
P01HL18974-03 0006 Experimental neurogenic
hypertension program ■ Model of sustained arterial
hypertension (cats)
POlHL-18974-03 0008 Experimental neurogenic
hypertension program ■ Monoamines and hypertension
(rats) .
ROlHL-19039-03 Circulation studies by one vs two circuit
model (dogs)
*• R01HL19048-03 Structure of baroreceptors in
hypertension (rats)
** ROlHL-19256-03 Arterial baroreceptors in cardiovascular
control (dogs)
ROIHL 19257 03 Cardiovascular adjustment to behavioral
stress (dog) ,
R01HL19467-03 Regulation of blood pressure (rats, dogs)
R01HL-2037102 Intravascular redistribution of blood
volume (dogs)
** ROlHL-21071-02 Mechanisms of hypertension in
coarctation of the aorta (dog)
** R01HL-2109401 Arterial baroreceptors and renal function
(dogs)
ROlHL-2115802 Cardiac receptors with vagal (--tiDer
afferents (cats)
ROlHL-21351-02 Renal and vascular control by
sympathetic ganglia (animals)
ROlHL-21436-02 Autonomic control of renal function
(cats)
ROlHL-21532-02 Cardiovascular homeostasis and learning
(frogs, rats, human)
S«N
• RO I HI 7179901 Circumvenlricular »ile» ol pre»»or »ct»n
of angiotentin II (rats)
• R01H122296 0I Autonomic mechtniimt in man
ROIHI 22482 01 Circulatory hemodynimici and lodium
oicielion (dogi) a , - .^a
ROIHL 22484 01 Neural control of cardiac conduction and
excitation (dogs) ,._... _.-
• ROIHL 22546 02 Baroreceptor reflex mechaniimi in man
•• ROIHL 22581 02 Neurocirculatory control in dubeHi
mellilus (human)
•• ROIHL 22594 01 Reflex control of the circulation in heart
failure (dogs)
ROIHL 22641 01 Ventilation, perfusion, and jyitemic
arterial reflexes (dogs)
•• ROIHL 22667 01 Mechanisms of baroreceptor adaptalwn
in hypertension (dogs)
•• R23HL 22669 01 Cardiovascular effects from visceral
afferents (dogs) ..„.i„
•• ROIHL 22715 01 Neural integration ol the cardiovascular
reflexes (dogs))
R23HL 22747 01 Cardiodynamics and hypertension under
cerebellar control (dogs)
ROIHL 2292801 Systematic study of bronchial circulation
(sheep)
SENSITIZATION PASSIVE
SEE HYPERSENSITIVITY. SENSITIZATION PASSIVE
SENSITIZATION TRANSFER FACTOR
SEE HYPERSENSITIVITY. TRANSFER FACTOR
(HYPERSENSITIVITY)
SENSITIZING ANTIBODIES HUMORAL
(CIRCULATING) (SERUM)
SEE HYPERSENSITIVITY. SENSITIZING ANTIBODIES HUMORAL
SENSITIZING ANTIBODIES NON-HUMORAL
SEE HYPERSENSITIVITY. SENSITIZING ANTIBODIES NON-
HUMORAL
SENSITIZING ANTIGENS
SEE HYPERSENSITIVITY, ALLERGENS
SENSORIMOTOR SYSTEMS (GENERAL)
SEE NEUROMOTOR SYSTEM, SENSORIMOTOR SYSTEMS
(GENERAL)
SENSORY DEPRESSION, ANESTHESIA (GENERAL)
SEE ALSO DISEASES. COMPLICATIONS. ANESTHESIA RELATED
SEE ALSO NEUROPHARMACOLOGICAL AGENTS, ANESTHETICS
SEE ALSO TEMPERATURE (BODY). HYPOTHERMIA INDUCED
PC1HL-06285-18 0181 Cardiovascular-respiratory
physiology and biochemistry - Regulation of respiration -
Role of vagus nerve (dogs)
** ROlHL-09609-11 Lung volume and breathing mechanics
during anesthesia (human) .
P01HL11678-U 0059 Cardiovascular dynamics and ineir
control - Basic hemodynamics (dogs, rats)
POIHL 12738-10 0111 Physiologic pharmacology and its
clinical applications - Cardiovascular pharmacology (dogs)
P01HL14388-07 0155 Regulation of the circulation in
pathological states - Cardiopulmonary afferent activity,
carotid chemo-baroreceptor reflexes
ROlHL-14529-07 Systems analysis of baroreflex (dogs)
ROlHL-15416-06 Cardiovascular control in normal and
disease states (dogs, baboons)
ROlHL-16454 03 Vascular muscle reactivity in
hypertension (human, rats)
ROlHL-16916-04 0011 The role of albumins in lung water
accumulation - Whole body distribution and exchange of
albumin (rabbits, human, monkeys)
** ROlHL-17314-04 Effects of anesthesia and loading on
respiration (human, cats)
** P50HL- 17665 04 0026 Study of ischemic heart disease •
Anesthesia -Myocardial ischemia and hemodynamics in
coronary disease (human)
ROlHL-17903-03 Regional circulatory responses to hypoxia
(rats. cats, rabbits)
" ROlHL-1925603 Arterial baroreceptors m cardiovascular
control (dogs)
POlHL-21584-02 0002 Respiratory mechanics in normal
and abnormal states - Lung mechanics -Regional
deformation and ventilation (dogs)
** POlHL-21584-02 0003 Respiratory mechanics in normal
and abnormal states - Effects of anesthesia on ventilation
and respiratory mechanics in man
** POlHL-21584-02 0004 Respiratory mechanics in normal
and abnormal states - Effects of anesthesia on respiratory
mechanics (dogs)
POlHL-2 1584-02 0005 Respiratory mechanics in normal
and abnormal states - Regulation and behavior of airway
smooth muscle (human, animals)
ROlHL-22910-01 Control of breathing pattern in health
and disease (human, animals)
SENSORY DEPRESSION, ANESTHESIA
(GENERAL), INHALATION
POlHL-06370-17 0006 Cardiopulmonary and renal
pathology research center - Chemical basis of
ultrastructural changes in disease (rats)
** ROlHL-13257-09 Inhalation anesthesia on myocardial
metabolism (dogs, swine, human)
ROlHL-13315-08 Disposition ot vasoactive hormones in
mammalian lung (rats, rabbits, human)
(contd)
•Excludes routine methodology OR covers only general projects which preclude
"Oriented significantly to above subject
indexing at the spccificlevel.
1^ Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
SEN
ROlHL-17091-05 Anesthetics and microvascular response
to hemorrhage (rats)
ROlHL-20754-02 Anesthetic-induced myocardial depression
(rabbits)
SENSORY DEPRESSION, ANESTHESIA,
REFRIGERATION
R01HL1920303 Surgical approach to congenital heart
diseases (dogs, primates)
ROlHL-20143-02 Hypothermic circulatory arrest-Cerebral
vascular change (dogs)
SENSORY DEPRESSION, ANESTHESIA
CONDUCTION
POlHL-06285-18 0181 Cardiovascular-respiratory
physiology and biochemistry - Regulation of respiration-
Role of vagus nerve (dogs)
POlHL-06296-18 0007 Cardiovascular and pulmonary
adaptation to stress • Cardiovascular control during
isometric exercise (cats)
SENSORY DEPRESSION, ANESTHESIA
CONDUCTION, LOCAL
POlHL-06285-18 0181 Cardiovascularrespiratoo
physiology and biochemistry ■ Regulation of respiration-
Role of vagus nerve (dogs)
R01HL1523105 Mechanisms of hemodynamic changes
during digestion (dogs)
ROlHL-19721-03 Lung inflammation-Lysosomal proteases
and liposomes (human, rabbits)
SENSORY DEPRESSION, ELECTRONARCOSIS
POlHL-08899-14 0045 Tolerance to respiratory gases in
health and disease • Studies in normal subjects
SENSORY FEEDBACK
ROlHL-15307-06 Central nervous control of renin and
blood pressure (dogs)
ROlHL-18823-02 Physiological correlates of conditioned
blood pressure (human)
SENSORY MECHANISMS (GENERAL)
SEE SENSORY-PERCEPTUAL PROCESSES, SENSORY
MECHANISI^S (GENERAL)
SENSORY NERVES
SEE NERVOUS SYSTEM, AFFERENT NERVES
SENSORY-PERCEPTUAL PROCESSES,
DISCRIMINATION
R01HL-19204-03 Environmental factors in hypertension
(Rhesus monkeys)
SENSORY-PERCEPTUAL PROCESSES, OLFACTORY
STIMULI
POlHL-08214-15 0006 Chemical and biological properties
of lipids • Analysis and properties of lipids
SENSORY-PERCEPTUAL PROCESSES, PAIN
SEE ALSO HEART DISORDERS, CORONARY, ANGINA PECTORIS
SEE ALSO NEUROLOGIC MANIFESTATIONS, HEADACHE
SEE ALSO SENSORY DEPRESSION, ANESTHESIA (GENERAL)
NOlHB-72916-02 Crisis and pain symptom prophylaxis by
oral zinc therapy (human)
POlHL-08682-15 0018 Regulation of the cardiovascular
system - Functional implications of cardiac afferent nerves
(dogs)
ROlHL-22732-01 Central organization of cardiac afferent
nerves (cats, monkeys)
SENSORY-PERCEPTUAL PROCESSES, PERCEPTION
SEE ALSO ENVIRONMENT, ORIENTATION
SEE ALSO EYE, VISUAL PERCEPTION
SEE ALSO SENSORYPERCEPTUAL PROCESSES,
DISCRIMINATION
*• POlHL-08899-14 0066 Tolerance to respiratory gases in
health and disease - Neurophysiological effects of inert
gases in man
SENSORY-PERCEPTUAL PROCESSES,
PROPRIOCEPTION
SEE ALSO EAR, LABYRINTH, VESTIBULAR APPARATUS
SEE ALSO EAR, LABYRINTH, VESTIBULAR REFLEX
SEE ALSO MUSCLE FUNCTION, MUSCLE STRETCH
(RECEPTORS)
SEE ALSO MUSCLE FUNCTION, MUSCLE STRETCH REFLEX
ROlHL-18007-05 Neural mechanisms controling motor act
of breathing (cats, human)
SENSORY-PERCEPTUAL PROCESSES, SENSORY
MECHANISMS (GENERAL)
SEE ALSO EYE, VISION
POlHL-08899-14 Tolerance to respiratory gases in health
and disease
Tolerance to respiratory gases in
Oxygen effects upon CNS and sensory
492
Tolerance to respiratory gases in
Inert gas influences upon visual
M
POlHL-08899-14 0043
health and disease
functions (human)
P01HL08899-14 0057
health and disease
man
POlHL-08899-14 0065
health and disease
Tolerance to respiratory gases in
Studies of intermittent exposure in
gases exposure (human)
Tolerance to respiratory gases in
Adaptation and effects of narcotic
POlHL-08899-14 0067
health and disease
function in man
** R01HL19995-02 Sensory transduction in cardiac
mechanoreceptors (cats, frogs, rats)
SENSORY-PERCEPTUAL PROCESSES, TASTE
THRESHOLD
P50HL-142 14-07 0028 Newborn lung center for hyaline
membrane disease - Relationship of trace metals to
respiratory failure (dog, sheep, human)
SENSORY-PERCEPTUAL PROCESSES,
THERMORECEPTION
POlHL-11414-11 0027 Thrombosis and atherosclerosis
program - Thermal memory wire filter to prevent pulmonary
embolism (human, dogs)
*• ROlHL-20766-02 Control of circulation in heat stress
(baboons)
SENSORY THRESHOLDS
SEE ALSO EAR. HEARING. AUDITORY THRESHOLD
SEE ALSO NEUROPHARMACOLOGICAL AGENTS. ANESTHETICS
SEE ALSO SENSORY DEPRESSION, ANESTHESIA (GENERAL)
SEE ALSO SENSORY-PERCEPTUAL PROCESSES, TASTE
THRESHOLD
P50HL-142 14-07 0027 Newborn lung center for hyaline
membrane disease ■ Oral-laryngeal chemoreceptors and
respiratory failure in newborns (human, sheep)
SEPTAL AREA
SEE BRAIN, LIMBIC SYSTEM, SEPTAL AREA
SEPTAL DEFECT HEART
SEE CONGENITAL ABNORMALITIES, HEART SEPTAL DEFECTS
SEPTAL DEFECT THERAPEUTIC
SEE HEART SURGERY. SEPTAL DEFECT THERAPEUTIC
SEPTICEMIA, SEPTICEMIC SHOCK
SEE BLOOD TOXICOLOGY, BACTEREMIA-SEPTICEMIA
SEPTUM HEART
SEE HEART, SEPTUM
SERINE
SEE AMINO ACIDS, SERINE
SEROLOGY
SEE IMMUNOLOGY, SEROLOGY*
SEROTONIN
SEE BENZOPYRROLES. SEROTONIN
SEROTONIN INHIBITORS
SEE BENZOPYRROLES. SEROTONIN INHIBITORS
SEROTYPES, SEROTYPING
SEE MICROBIAL IDENTIFICATION AND CLASSIFICATION,
SEROTYPING
SERPASIL
SEE ALKALOIDS, RAUWOLFIA TYPE, RESERPINE
SERRATIA MARCESCENS
SEE BACTERIA, ENTEROBACTERIACEAE, SERRATIA
MARCESCENS*
SERUM
SEE BLOOD AND RE SYSTEM, BLOOD, SERUM
SERUM ALBUMIN
SEE ALBUMINS. SERUM ALBUMIN
SERUM ALBUMIN BOVINE
SEE ALBUMINS. SERUM ALBUMIN BOVINE
SERUM AMINO ACIDS
SEE AMINO ACIDS. SERUM AMINO ACIDS
SERUM GLOBULINS
SEE GLOBULINS, SERUM GLOBULINS
SERUM HEPATITIS
SEE LIVER DISORDERS, HEPATITIS SERUM
SERUM HEPATITIS VACCINE
SEE VACCINES, VIRAL, HEPATITIS, SERUM
SERUM LIPIDS
SEE LIPIDS BLOOD
SERUM LIPOPROTEINS
SEE LIPOPROTEINS BLOOD
SERUM PROTEINS
SEE BLOOD PROTEINS
SERUM PROTHROMBIN CONVERSION
ACCELERATOR
SEE BLOOD COAGULATION, FACTOR VII
SERUM SICKNESS
SEE HYPERSENSITIVITY, SERUM SICKNESS
SERVOMECHANISMS (BIOLOGICAL)
SEE INFORMATION PROCESSING AND CONTROL (BIOLOGICAL)
SERVOMECHANISMS (NEURAL)
SEE INFORMATION PROCESSING AND CONTROL (NEURAL)
SEX
SET, MENTAL
SEE PSYCHOLOGY, AHITUOES (AND RELATED)
SEVENTH DAY ADVENTISTS
SEE SOCIAL GROUPS, RELIGIOUS, SEVENTH DAY ADVENTISTS
SEX
ROlHL-17776-04 Pulmonary mucus transport in
obstructive lung diseases (human)
ROlHL-18805-04 0007 Sudden cardiac death and the
onset of myocardial infarction - Analysis of pathologic
factors involved in sudden death (human)
ROlHL-22123-02 The role of the red cell in diabetic
atherosclerosis (human)
ROlHL-22739-01 Evolution and progression of pediatric
atherosclerosis
SEX, FEMALE
SEE ALSO AGE (ANIMAL), PUBERTY
SEE ALSO CHILD DEVELOPMENT, PUBERTY
SEE ALSO FAMILY. MATERNAL BEHAVIOR
SEE ALSO FERTILITY. SEX CYCLES, MENSTRUATION
SEE ALSO HEALTH CARE SERVICES, MATERNAL AND INFANT
CARE
SEE ALSO NEOPLASMS DIAGNOSIS, BREAST NEOPUSMS
DIAGNOSIS. MAMMOGRAPHY*
SEE ALSO PREGNANCY
SEE ALSO PREGNANCY DISORDERS
ROlHL-20179-02 Epidemiology of sudden cardiac death
among women
ROlHL-20535-02 Cardiovascular disease and evolving
diabetes mellitus (human)
POlHL-20993-02 0003 Population dynamics of arterial
cells in atherogenesis Clonal phenomena in atherogenesis
(human, hares)
ROlHL-21352-02 Community studies of obstructive lung
disease (human)
SEX, MALE
SEE ALSO AGE (ANIMAL), PUBERTY
SEE ALSO CHILD DEVELOPMENT, PUBERTY
SEE ALSO FERTILITY, SPERM (ALL STAGES)
ROlHL-04697-17 International heart disease epidemiology
(human)
POlHL-06308 18 0010 Mechanisms and therapy of
circulatory disease ■ Ventricular arrhythmias during exercise
to CHD and myocardial ischemia (human)
POlHL-07896-15 0055 Environmental biomedical research
program Cerebral blood flow by Xenon-133 inhalation
(human)
POlHL-08974-14 0005 Natural and experimental
atherosclerosis - Atherosclerosis, coronary heart disease
and sudden death (human)
ROlHL-10445-09 Cooperative study of drugs and coronary
heart disease (men)
ROlHL-16908-04 Myocardial function, risk factors and
future CHD (men)
ROlHL-16909-04 Myocardial function, risk factors and
future CHD (men)
ROIHL- 17580-04 The impact of stress on coronary heart
disease (men)
ROlHL-18776-04 Prevention of acute and fatal
cardiovascular disease (human)
R01HL-20034-03 Hypertension-Psychophysiologic and
genetic precursors (human)
ROlHL-20374-03 Myocardial function-Risk factors and
future CHD (human)
Etiology of myocardial infaction (human)
Autonomic mechanisms in man
Behavior patterns, stress, and
Prevention of coronary heart disease
R01HL-20645-01
ROlHL-22296-01
ROlHL-22514-01
catecholamines
NOlHV-22971-07
(human)
NOlHV-2297607 Multiple risk factor intervention trial,
prevention of coronary heart disease
NOlHV-22977-08 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22979-07 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22980-06 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-22981-10 Intervention trial (or the prevention of
coronary heart disease (human)
NOlHV-22982-07 Intervention trial for prevention of
coronary heart disease (human)
NOlHV-22983-07 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-33101-06 Development and conduct of a multiple
risk factor intervention trial (human)
NO lHV-33 105-09 Intervention trial for prevention of
coronary heart disease (human)
NOlHV-33106-06 Intervention trial for the prevention of
coronary heart disease (human)
NOIHV-331 10-04
(human)
NOlHV-42902-08
disease (human)
NOlHV-42929-08
Prevention of coronary heart disease
Epidemiological studies of coronary heart
•Excludes routine methodology OR covers onti general projects which preclude indexing at the specific level
••Onented significantly to above subject
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
Risk factor intervention trial for the
prevention of CHD (human)
NOlHV-42930-09 Risk factor intervention trial for the
prevention of CHD (human)
NOlHV-42932-05 Risk factor intervention trial for the
prevention of CHD (human)
(contd)
SKE
SEX
NOIHV 42933 09 Multlplt cisk lictois in coronsiY heart
disease (human)
NOIHV 53010 03 NAS NRC twin rejisliY
NOIHV 62955 04 Data collection in clinical pathology and
moibid anatomy (men)
SEX, SEX DIFFERENCE
ROIHI 04697 17 International heart disease epidemiology
(human)
POIHL 06835 17 0064 Cacdiowasculat disease Mudies
in atheiosclerosis (human, animals)
ROIHL 08888 12 Coopefative study ol drugs and coronary
heart disease (men)
POIHI 08974 14 0028 Natural and e«perimental
atherosclerosis Geographic pathology ot atherosclerosis
and coronary heart disease (human)
ROIHL 10705 09 Cooperative study ol drugs and coronary
heart disease (men)
R01HL11372 08 Cooperative study ot drugs and coronary
heart disease (men)
ROIHL 12766 09 Structure function relation ol blood
vessels (rats, monkeys)
ROIHL 13632-08 Vascular changes in diabetes mellitus
(human) . .
POIHL 14388-07 0208 Regulation of the circulation in
pathological states Baroreceptor retlex function in normal
and hypertensive man
POIHL 14414 07 0008 Environmental influences on
cardiorespiratory and cellular functions ■ Energetics of
swimming (human)
ROIHL 17408 03 Fresh blood rheology-Relation to
cardiovascular risk (human)
•• ROIHL 1751604 Role of androgen as a risk factor in
atherogenesis (human, animals)
ROlHL-17732-03 Peripheral venomotor control in thermal
stress (human)
ROlHL-17865-04 Studies on aging -Effects of sex
hormones (rats, dogs)
ROlHL-18002-03 Circulatoiy shock, trauma and REsystem
function (rats) . zu i
R01HL18715-02 Hypertension incidence proiect (human)
ROlHL-19056-03 Blood triglycerides and lipoprotein lipase
in the lung (rats)
R01HL19451-03 0003 Functional characteristics ot the
left heart - Lett ventricular segmental contraction (human,
dogs) .
ROlHL-1986403 0001 Blood pressure of children and
young adults - Follow up of students from Dormont.
Pennsylvania
ROlHL-1986903 Antecedents of adolescent hypertension
(human) „u i j
R01HL19870-03 Hypertensive progeny -Physical and
humoral precursor search
ROlHL-19929-03 High blood pressure in the young.
prevalence and precursors (human)
ROlHL-19956-03 High blood pressure in the young
(human)
ROlHL-20373-02 Cardiovascular aging in young men ana
women
ROlHL-20381-03 Long-term study of diabetic vascular
disease (human)
ROlHL-20471-03 Atherosclerosis and diabetes mellitus
(human)
POlHL-20581-01 0005 Vascular neuroetfector
mechanisms in health and disease - Changes in the
neuroetfector mechanism in hypertension (rabbits)
ROlHL-20875-02 Chronic obstructive pulmonary disease-
Familial/genetic (human)
ROlHL-20954-02 Hyperlipoproteinemia (rats, human)
ROlHL-2141802 Experimental myocardial infarction (rats)
R23HL-21917-01 Adrenal steroids in adolescent and adult
hypertension
ROlHL-21996-01 Alteration of digitalis and aldosterone
disposition (rats, rabbits, mice, dogs)
ROlHL-22040-01 Regulation of lysyl-cross-linking in
vascular tissue (rats, turkeys)
ROlHL-22812-01 Regulation of hepatic production ot HUL
(rats)
ROlHL-23201-01 Mechanisms of hypertension (human.
rats)
NOlHR-32900-09 Pilot study to standardize the
measurement of 'closing volume' (human)
NOlHR-32902-07 Pilot study to standardize the
measurement of closing volume (human)
SEX CHROMOSOMES
SEE GENETICS. CHROMOSOMES. SEX CHROMOSOMES
SEX DIFFERENCE
SEE SEX. SEX DIFFERENCE
SEX HORMONES
SEE REPRODUCTIVE HORMONES. SEX HORMONES
SH ANTIGEN
SEE IMMUNOLOGY, ANTIGENS VIRAL. HEPATITIS B ANTIGEN
(HBAG)
SHARED SERVICES, HOSPITAIS AND OTHER
FACILITIES
SEE HEALTH CARE SERVICES, SHARED SERVICES
SHEEP
SEE MAMMALS. ARTIGDACTYLA. SHEEP*
SHELLFISH POISONING PARALYTIC
Sit lOXICOIOGY. PROIO/OAl lOXINS. SAXIIOXIN
SHELTERED CARE INSTITUTIONS
Slf HfAIIH CARf fAClLIIIES. RESIOtNIIAl
SHIVERING
Sff IFMPERAIURF (BODY) RfGUUTION
SHOCK
SEE INIURIES. SHOCK
SHOCK, ANAPHYLACTIC
SEE HYPERSENSITIVITY, ANAPHYLAXIS
SHOCK, CARDIOGENIC
SEE HEAR I DISORDERS, CARDIOGENIC SHOCK
SHOCK, HEMORRHAGIC
SEE CARDIOVASCUUR DISORDERS, HEMORRAGIC SHOCK
SHOCK, LUNG
SEE RESPIRATORY DISORDERS, RESPIRATORY
INSUFFICIENCY, SHOCK LUNG
SHOCK, SEPTICEMIC
SEE BLOOD TOXICOLOGY, BACTEREMIA-SEPTICEMIA
SHOCK, TOXIC
SEE INJURIES, SHOCK, TOXIC
SHUNTS, ARTERIOVENOUS ABNORMAL
SEE CARDIOVASCULAR DISORDERS, ARTERIOVENOUS SHUNTS
ABNORMAL
SHUNTS, ARTERIOVENOUS NORMAL
SEE CARDIOVASCULAR SYSTEM. ARTERIOVENOUS
ANASTOMOSIS NORMAL
SHUNTS, CARDIOVASCULAR ABNORMAL
SEE CONGENITAL ABNORMALITIES. CARDIOVASCULAR SHUNTS
ABNORMAL
SHUNTS, CARDIOVASCULAR SURGICAL
SEE CARDIOVASCULAR SURGERY. CARDIOVASCULAR SHUNTS
SHUNTS, COLLATERAL CIRCULATION NORMAL
SEE CARDIOVASCULAR SYSTEM, BLOOD SUPPLY, COLLATERAL
CIRCULATION
SHUNTS, DUCTUS ARTERIOSUS EMBRYONIC
SEE CARDIOVASCULAR SYSTEM, DUCTUS ARTERIOSUS
EMBRYONIC
SHUNTS, HEART BYPASS SURGICAL
SEE CARDIOVASCULAR SURGERY, CIRCULATORY ASSIST,
HEART BYPASS SURGICAL
SHUNTS, HEART-LUNG BYPASS
SEE CARDIOVASCULAR SURGERY, CIRCULATORY ASSIST,
HEART LUNG BYPASS
SHUNTS, HEART SEPTAL DEFECTS
SEE CONGENITAL ABNORMALITIES, HEART SEPTAL DEFECTS
SHWARTZMAN PHENOMENON
SEE HYPERSENSITIVITY, ANAPHYLAXIS, SHWARTZMAN
PHENOMENON
SIALIC ACIDS
SEE SUGAR ACIDS, SIALIC ACIDS
SIALIDASE
SEE CARBOHYDRASES, NEURAMINIDASE
SICKLE CELL ANEMIA
SEE HEMOPROTEINS, HEMOGLOBINOPATHIES, SICKLE CELL
ANEMIA
SICKLE CELL CRISIS
SEE HEMOPROTEINS, HEMOGLOBINOPATHIES, SICKLE CELL
CRISIS
SICKLING INHIBITORS
SEE HEMOPROTEINS, HEMOGLOBINOPATHIES. SICKLING
INHIBITORS
SIDEROBLASTIC ANEMIA
SEE BLOOD AND RE DISORDERS, ANEMIA SIDEROBLASTIC
SIDEROPHILIN
SEE METALLOPROTEINS, TRANSFERRIN
SIDS
SEE CHILDREN, INFANT AND CHILD MORTALIH, SUDDEN
INFANT DEATH SYNDROME
SIEVES, MOLECULAR
SEE PHYSICAL SEPARATION, MOLECULAR SIEVES*
SIGNS AND SYMPTOMS (NOT GROUPED
ELSEWHERE)
SEE DISEASES. SIGNS-SYMPTOMS (NOT GROUPED
ELSEWHERE)
SILAGE
SEE FOOD. ANIMAL FEEDS, SILAGE
SILASTIC
SEE PLASTICS. SILICONE RUBBER
SILICATES
•• P50HI 14212 0/ 0012 Correlated iludiei ot pulmonery
fibiosi% Inorganic partirulales in tobacco, imoke end
lungs ol cigarette imokci-. (human)
•• P50HI 15092 07 0002 Immune and librotic retponw to
occupational environments Longitudinal study ol
ssndblasters silicosis (human)
P50HL 15092 07 0006 Immune and libiotic response to
occupational environments Immunologic studies m
silicosis (human, labbrts, hamsters, guinea pigs)
P50HL 15092 07 000/ Immune and fibrotic response to
occupational environments Asbestosis Cellular immunity,
structure and mineral localization (human)
P50HL 15092 07 0014 Immune and fibrotic response to
occupational environments Clinical immur-ology core
resource .
P60HL 17292 04 0005 Vermont Lung Center Mineral
pneumoconioses Pathogenesis and pathology (human)
ROIHL 2112002 Membrane dynamics in alveolar
macrophages (rabbits)
SILICATES, ASBESTOS
•• P50HL 15092 07 0001 Immune and fibrotic response to
occupational environments X ray diffraction study Dust
exposure in asbestos cement products manufacturing
•* P50HL 1509207 0007 Immune and fibrotic response to
occupational environments Asbestosis Cellular immunity,
structure and mineral localization (human)
•* P50HL 15092 07 0008 Immune and fibrotic response to
occupational environments Animal models of asbestosis
(hamsters)
P50HL 15092-07 0014 Immune and fibrotic response to
occupational environments Clinical immunology core
resource ^ ^ _,
*• ROlHL-17543-03 0002 Magnetic tracers for diagnosis ot
lung disease - Magnetite as an index of asbestos exposure
(human) ,
ROlHL-17543-03 0003 Magnetic tracers for diagnosis ot
lung disease Occupationally accumulated magnetite for
diagnosis of lung disease (human)
R01HL17543-03 0004 Magnetic tracers for diagnosis of
lung disease - Magnetite retention, distribution, relaxation
rate, viscosity (rabbits)
R23HL 19584 01 Alveolar macrophage responses to toxic
particle exposure (guinea pigs, human)
SILICATES, GLASS
ROlHL-20079-02 0003 Thromboresistant material - Blood
surface interactions (human, cattle)
SILICON
** POlHL-06312-17 0050 Surgical cardiology ■ Prevention of
pericardial and pleural adhesions by silicone oil (dogs)
** NOlHV-32949-n Modification of silicon elastomers for
medical devices
SILICONE RUBBER
SEE PLASTICS, SILICONE RUBBER
SIMIAN VIRUS SV40
SEE VIRUSES, PAPOVAVIRUSES, SV40 VIRUS
SIMMONDS DISEASE
SEE PITUITARY GLAND DISORDERS, HYPOPITUITARISM
SINGLE CELL ANALYSIS
SEE CELLS. SINGLE CELL ANALYSIS
SINGLE FILE PORE DIFFUSION
SEE BIOLOGICAL TRANSPORT. PASSIVE TRANSPORT,
DIFFUSION
SINGLE UNIT (CELL) ANALYSIS
SEE CELLS, SINGLE CELL ANALYSIS
SINGLE UNIT TRAINING (AUTOGENIC)
SEE PSYCHOLOGY, CONDITIONING, AUTOGENIC AND INTERNAL
CONTROL
SINGLET STATE
SEE ELECTRONIC SPECTRA, SINGLET STATE
SINO-ATRIAL NODE
SEE HEART. CONDUCTION SYSTEM, SINOATRIAL NODE
SINUSES INTRACRANIAL VENOUS
SEE CEREBROVASCULAR SYSTEM, VENOUS SINUSES
INTRACRANIAL
SITOSTEROL
SEE CHOLESTANE SERIES, SITOSTEROL
BETA-SITOSTEROL
SEE CHOLESTANE SERIES, BETA-SITOSTEROL
SIZING OF MYOCARDIAL INFARCT
SEE HEART DISORDERS DIAGNOSIS, MYOCARDIAL INFARCT
SIZING
SJOGREN'S SYNDROME
SEE CONNECTIVE TISSUE DISORDERS, SJOGREN'S SYNDROME
SKELETAL DISORDERS (GENERAL)
ROlHL-11901-12 0018 Effects of metabolic surgery on
the hyperlipidcmias - Jejunoileal bypass -Postoperative
complications (human)
(contd)
•Excludes routine methodology OR covers only general projects which preclude
"Oriented significantly to above subject
indexing at the specific level.
M Grant has sutjprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
SKE
SKELETAL DISORDERS, ARTHRITIS
SEE ALSO PURINES-PYRIMIDINES METABOLISM ERRORS,
GOUT
R01HL1190112 0018 Effects of metabolic surgery on
the hyperlipidemias • Jejunoileal bypass-Postoperative
complications (human)
R01HL19839-09 Factors in youth predisposing to chronic
diseases (former college students)
SKELETAL DISORDERS, ARTHRITIS, RHEUMATOID
SEE ALSO CONNECTIVE TISSUE DISORDERS. SJOGREN'S
SYNDROME
R01HL00487-29 Vasomotor tone and venous return
(human, dogs, monkeys )
SKELETAL DISORDERS, BONE DEVELOPMENT,
DWARFISM
SEE ALSO METABOLIC DISORDERS INBORN. GLYCOGENOSIS
ROlHL-09921-13 Mechanisms related to congestive heart
failure (dogs, human, rat)
SKELETAL DISORDERS, BONE DEVELOPMENT,
DWARFISM, PITUITARY
RC1HL191 75-03 Pituitary modulation of micro-and macro-
vascular disease (human, rats)
SKELETAL DISORDERS, BONE METABOLISM,
OSTEOPOROSIS
POlHL-04664-18 0008 Cardiovascular and lung dynamics
- Micrographic video imaging technique
SKELETAL DISORDERS, BONE NECROSIS
POlHL-08899-14 0028 Tolerance to respiratory gases in
health and disease ■ Inert gas exchange, oxygen influences-
organs and tissues (human, rabbits, dogs)
SKELETAL DISORDERS, BONE NECROSIS
ISCHEMIC
P60HL1516905 0014 Support for center for sickle cell
disease Orthopaedic aspects of sickle cell disease
(human)
SKELETAL DISORDERS, ORTHOPEDICS
SEE ALSO SKELETAL SYSTEM. LIMB. AMPUTATION
" P60HL-15I69-05 0014 Support for center for sickle cell
disease • Orthopaedic aspects of sickle cell disease
(human)
SKELETAL DISORDERS, ORTHOPEDICS, HIP
PROSTHESIS
P60HL-15169-05 0014 Support for center for sickle cell
disease ■ Orthopaedic aspects of sickle cell disease
(human)
ROlHL-1797403 External pneumatic compression in deep
venous thrombosis (human)
R01HL18738-02 Prevention of postoperative venous
thrombi (human, cattle)
SKELETAL DISORDERS, ORTHOPEDICS, HIP
SURGERY
SEE ALSO SKELETAL DISORDERS. ORTHOPEDICS, HIP
PROSTHESIS
ROlHL-13754-08 Postoperative thromboembolism in
surgical patients (human)
P50HL14217-08 0063 Specialized center of research in
thrombosis ■ Special clinical studies laboratory
SKELETAL DISORDERS, OSTEITIS DEFORMANS
** POlHL-14388-07 0231 Regulation of the circulation in
pathological states - Mechansim of cutaneous
vasodilatation in Paget's disease of bone
ROlHL-1755104 Biosynthesis and metabolism of
procollagen (human, monkeys, mice)
SKELETAL DISORDERS, OSTEOMYELITIS
P60HL 15169-05 0014 Support for center for sickle cell
disease - Orthopaedic aspects of sickle cell disease
(human)
SKELETAL DISORDERS, SPINAL CURVATURES,
KYPHOSIS
ROIHL-22022 01 Respiratory muscle dysfunction in
respiratory failure (human)
SKELETAL DISORDERS, SPINAL CURVATURES,
SCOLIOSIS
POIHL 10436-13 0008 A multidisciphnary study of
congenital heart disease - Physiologic consequences of
chronic hypoxemia (human)
** ROlHL-12530-10 Emphysema -Respiratory function in
disease (human, dogs, rats)
SKELETAL DISORDERS DIAGNOSIS (INCL
EXAMS)*
SEE ALSO BODY PHYSICAL CHARACTERISTICS (GENERAL)
SEE ALSO MUSCLE FUNCTION. ELECTROMYOGRAPHY*
POIHL-04664 18 0008 Cardiovascular and lung dynamics
- Micrographic video imaging technique
SKELETAL MOVEMENT, LIMBS MOVEMENT
ROlHL-13233-08 Cardiorespiratory control in exercise
(human)
494
SKELETAL MOVEMENT, POSTURE
P01HL04564-18 0002 Cardiovascular and lung dynamics
X-ray cross section imaging of organs (dogs)
P01HL12373-10 0003 Cardiopulmonary physiology and
pathophysiology - Myocardial function in man
ROlHL-14495-05 Solid and structural mechanics of lungs
(mammals)
POlHl-14580-07 0005 Program project in respiratory
mechanics - Development and evaluation of tests of
pulmonary function (human)
ROlHL-16918-05 Role of steroids in hypertension (human)
ROlHL-17364-04 Big renin -Biochemical and clinical
studies (human)
ROlHL-21274-01 Prorenin -Physiological and biochemical
analysis (human)
ROlHL-2144402 Pulmonary mechanics during postnatal
development (human)
ROlHL-21518-01 Improvement in regional ventilation-
perfusion resolution (human)
M POlHL-2158402 Respiratory mechanics in normal and
abnormal states
POlHL-21584-02 0002 Respiratory mechanics in normal
and abnormal states ■ Lung mechanics-Regional
deformation and ventilation (dogs)
** POlHL-21584-02 0003 Respiratory mechanics in normal
and abnormal states - Effects of anesthesia on ventilation
and respiratory mechanics in man
POlHL-21584-02 0004 Respiratory mechanics in normal
and abnormal states - Effects of anesthesia on respiratory
mechanics (dogs)
ROlHL-21893-01
(human)
ROlHL-22506-01
Blood volume distribution in hypertension
Hemodynamics of the clinical
hypertensions
ROlHL-22977-01 Role of vasoconstrictor mechanisms In
heart failure (human, dogs)
ROlHL-23201-01 Mechanisms of hypertension (human,
rats)
SKELETAL SYSTEM (GENERAL)
SEE ALSO MUSCLES
ROlHL-018 13-25 Regulation of metabolism by drugs and
hormones (rats)
POlHL-14414-07 0008 Environmental influences on
cardiorespiratory and cellular functions - Energetics of
swimming (human)
** ROlHL-17376-04 Analysis of Z bands in heart by optical
diffraction (mammals)
** POlHL-19737-02 0009 Cellular and molecular aspects of
respiratory physiology ■ Regulation of tissue oxygen tension
and body carbon monoxide stores (human, dogs)
** POlHL-20592-02 0012 Cell biology of cardiac and
skeletal muscle - Contractile properties of skinned muscle
fibers (frogs)
SKELETAL SYSTEM, BONE
SEE ALSO SKELETAL SYSTEM (GENERAL)
** POIHL- 169 10-05 0008 Regulation of the peripheral
circulation - Circulation to bone (dogs, baboons)
R23HL-19601-01 Cardiac response to chronic metabolic
acidosis (rats)
SKELETAL SYSTEM, BONE DENSITY
P01HL04664-18 0008 Cardiovascular and lung dynamics
- Micrographic video imaging technique
SKELETAL SYSTEM, CARTILAGE
** POlHL-11310-12 0104 Mechanisms of cardiovascular
disease - Structure of connective tissue proteoglycans
(rabbits)
ROlHL-216 12-02 Biochemistry of lung proteoglycans
(human, rabbits)
SKELETAL SYSTEM, HIP, FEMORAL HEAD
P60HL 15169-05 0014 Support for center for sickle cell
disease - Orthopaedic aspects of sickle cell disease
(human)
SKELETAL SYSTEM, JOINT, KNEE
R01HL19255-03 Evaluation of diagnostic clinical
hemorrheology (human)
SKELETAL SYSTEM, LIMB
SEE ALSO SKELETAL MOVEMENT, LIMBS MOVEMENT
P50HL-17651-04 0044 Ischemic heart disease specialized
center of research ■ Limb blood flow after myocardial
revascularization (human)
ROlHL-20766-02 Control of circulation in heat stress
(baboons)
SKELETAL SYSTEM, LIMB, AMPUTATION
ROlHL-17974-03 External pneumatic compression in deep
venous thrombosis (human)
** ROlHL-221 13-02 Micro/macrovasculature in healing of
foot lesions (human)
SKELETAL SYSTEM, LIMB, ARM
ROlHL-21323-02 Raynaud's disease and temperature self-
regulation (human)
SKELETAL SYSTEM, LIMB, FINGERS
** ROlHL-1846703 Fingertip blood flow In normals and
Raynaud's disease (human)
ROIHL 21323-02 Raynaud's disease and temperature self-
regulation (human)
"Excludes routine methodology OR covers only general proiects which preclude indexing at the specific level
•Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects
See Appendix (or investigator's name and grant number
SKI
SKELETAL SYSTEM, LIMB, HAND
SEE ALSO SKELETAL SYSTEM, LIMB. FINGERS
ROlHL-21323-02 Raynaud's disease and temperature self-
regulation (human)
SKELETAL SYSTEM, LIMB, LEG
SEE ALSO CARDIOVASCULAR SYSTEM. ARTERIES, FEMORAL
ARTERY
SEE ALSO NEUROMOTOR DISORDERS, PARALYSIS,
PARAPLEGIA
SEE ALSO SKELETAL SYSTEM. JOINT. KNEE
ROlHL-221 13-02 Micro/macrovasculature in healing of
foot lesions (human)
SKELETAL SYSTEM, RIBS
NO IHV- 72934-01 Development of a left heart assist blood
pumps (human, cattle)
SKELETAL SYSTEM CIRCULATION
ROlHL-15390-12 Regulation of blood flow in the
microcirculation
** POlHL-16910-05 0008 Regulation of the peripheral
circulation - Circulation to bone (dogs, baboons)
SKELETAL TISSUE PROSTHESIS, BONE
NOlHV-72934-01 Development of a left heart assist blood
pumps (human, cattle)
SKELETAL VISUALIZATION, BONE SCANNING*
POIHL-04664- 18 0008 Cardiovascular and lung dynamics
Micrographic video imaging technique
SKIN (GENERAL)
SEE ALSO ALBUMINOIDS, KERATOHYALIN
SEE ALSO GROWTH FACTORS (INCL. ANABOLICS), EPIDERMAL
GROVKTH FACTOR
P50HL-14 141-05 0003 SCOR for atherosclerosis in
childhood ■ Detection of abnormalities in lipid metabolism
(human, rabbits, rats)
ROlHL-20634-01 Blood volume and venous return in
thermal strain (human)
ROlHL-2145101 Control of circulation during heat stress
and fever (baboon)
ROlHL-21632-02 Development of a transcutaneous power
transfer system (cattle)
** ROlHL-22327-01 Transport of arterial blood gases through
skin (swine)
SKIN ABSORPTION
POlHL-08899-14 0079 Tolerance to respiratory gases In
health and disease - Physiological factors in
counterdiffusion bubble formation (human, pigs)
SKIN CIRCULATION
** ROlHL-20663-02 Regulation of skin blood flow in man
ROlHL-221 18-02 Microcirculation in patients with diabetes
mellltus
SKIN DISORDERS
SEE ALSO DISEASES, SIGNS-SYMPTOMS, HIRSUTISM
SEE ALSO METABOLIC DISORDERS (INBORN), PORPHYRIA
SEE ALSO SKIN ULCERS
POlHL-0889914 0029 Tolerance to respiratory gases in
health and disease - Isobaric gas counter diffusion
phenomena (human, pigs)
" ROlHL-22699-01 Defibrillation electrode studies (dogs,
swine)
SKIN DISORDERS, ERYTHEMA
SEE ALSO CONNECTIVE TISSUE DISORDERS. LUPUS
ERYTHEMATOSUS SYSTEMIC
ROlHL-22547-01 Behavioral treatment of Raynaud's
disease (human)
SKIN DISORDERS CONGENITAL
SEE CONGENITAL ABNORMALITIES, SKIN (GENERAL)
SKIN SECRETIONS, SWEAT
P50HL-19157-02 0007 Studies in cystic fibrosis and
bronchiolitis ■ Analysis of cystic fibrosis factors (human)
ROlHL-20634-01 Blood volume and venous return in
thermal strain (human)
ROlHL-20663-02 Regulation of skin blood flow In man
SKIN SENSITIZING ANTIBODIES
SEE HYPERSENSITIVITY, SKIN SENSITIZING ANTIBODY
SKIN TESTS, HYPERSENSITIVITY
SEE HYPERSENSITIVITY TESTS SKIN
SKIN TRANSPLANTATION
R01HL01623-24 Antigens related to graft rejection
(rabbits, rats)
POlHL-06314-17 0066 Immunologic mechanisms in
cardiovascular disease - Sensitization, cell-mediated
cytotoxicity, role of lymphocytes (human, mice)
R01HL11945-10 Synthesis of artificial lung and kidney
systems (sheep, mice, swine)
POlHL-13108-09 0010 Clinical heart transplantation -
Serum factors inhibiting lymphocyte responses in MLC
(human, bush babies)
POlHL-13 108-09 0012 CMnical heart transplantation ■
Human T cell sheep erythrocyte receptors
POlHL-13108-09 0015 Clinical heart transplantation -
Antithymocyte globulin analysis and clinical effects
(contd)
SKI
POIHI 1310809 0016 Clinic«l heart lunsplantalion
Total lymphoid iiiadiation lot immune response (dojs)
ROIHL 16828 04 GiadienI and transport ol o«ygen in
tissue and otgans (mammals)
POIHI 18646 03 0001 Studies basic to heart
tiansplantation Individualized legulalion ol
immunosuppfossion (dogs, lats)
POIHI 18646 03 0002 Studies basic to heart
tiansplantation Detection ol (election (dogs)
•• PCIHI 18646 03 0003 Studies basic to heart
tiansplantation Host lesponses to xenogcalls (lodents.
labbits)
POIHL 1864603 0006 Studies basic to heart
tiansplantation Reduction oi elimination ot existing
piesensitization (human, animals)
SKIN ULCERS
SEE ALSO CARDIOVASCULAR DISORDERS. VARICOSE ULCER
•* POIHL 08899 14 0029 Tolerance to lespiiatory gases in
health and disease Isobaiic gas countei dillusion
phenomena (human, pigs)
P60HL 23282 01 0003 Comprehensive hospital/community
sickle cell centei Tieatment of sickle cell ulceis with
physical therapy and vitamin E (human)
SLEEP
SEE PSYCHIC ACTIVITY LEVEL. SLEEP
SLEEP APNEA
SEE RESPIRATORY FUNCTION. HYPOVENTIUTION.
RESPIRATORY CENTER DYSFUNCTION
SLEEP DISORDERS
SEE NEUROLOGIC MANIFESTATIONS. SLEEP DISORDERS
SLEEP WALKING
SEE NEUROLOGIC MANIFESTATIONS, SLEEP DISORDERS
SLOW POTENTIALS
SEE ELECTROPOTENTIALS. SLOW POTENTIALS
SLOW REACTING SUBSTANCES
SEE ALSO FATTY ACIDS, UNSATURATED FATTY ACIDS.
PROSTAGUNDINS
P50HL-14153-07 0013 Johns Hopkins Lung Center-
Chronic diseases of aliways - Pulmonaiv mechanics and
mediators of alleigic reactions (guinea pigs, human)
P50HL-14153-07 0014 Johns Hopkins Lung Centei-
Chionic diseases of airways - Mediator release in asthma
(human)
M POlHL-17382-05 Chemical mediators of acute pulmonary
disorders
POlHL-1 7382-05 0003 Chemical mediators of acute
pulmonary disoideis ■ Chemical mediatois relevant to
alleigic reactions (human, guinea pigs)
R01HL17873-04 Pathophysiology of exercise-induced
asthma (human)
** ROlHL-2187401 SRSA-lts biosynthesis and action
SLOW RELEASE PREPARATIONS (DRUGS)
SEE DRUGS, SLOW RELEASE PREPARATIONS
SLOW VIRUS DISEASES
SEE VIRUS DISEASE CHARACTERISTICS, LATENT DORMANT
OR SLOW
SLUMS
SEE SOCIOENVIRONMENT, URBAN POVERTY AREAS
SMALL LYMPHOCYTE DEPENDENT IMMUNE
SYSTEM
SEE IMMUNITY, CELLULAR IMMUNITY (GENERAL)
SMOG
SEE AIR POLLUTION
SMOKE INHALATION POISONING (OTHER THAN
TOBACCO SMOKING)
SEE TOXICOLOGY, GAS POISONING, SMOKE INHALATION
SMOKING TOBACCO
SEE PSYCHOLOGY, HABITS, SMOKING
SMOLDERING VIRUS DISEASES
SEE VIRUS DISEASE CHARACTERISTICS, LATENT DORMANT
OR SLOW
SMOOTH MUSCLE
SEE MUSCLES, SMOOTH MUSCLE
SNAKE BITES AND VENOMS
SEE TOXICOLOGY, ANIMAL POISONS, REPTILE
SNEEZING
SEE RESPIRATORY SYSTEM REFLEXES
SOCIAL ADJUSTMENT
SEE PSYCHOLOGY SOCIAL, SOCIAL ADJUSTMENT
SOCIAL BEHAVIOR
SEE PSYCHOLOGY SOCIAL, SOCIAL BEHAVIOR
SOCIAL CLASS
SEE SOCIOECONOMICS, SOCIAL CLASS
SOCIAL CONFORMITY
SEE PSYCHOLOGY SOCIAL, SOCIAL CONFORMITY
495
SOCIAL CONTROL, HEALTH
Sff HtAlTH SOCIAl CONTROL
SOCIAL DEPRIVATION
StE PSYCHOSOClAl ISOLATION DEPRIVATION
SOCIAL DOMINANCE
SEE PSYCHOLOGY SOCIAl, GROUP PROCESSES. SOCIAl
DOMINANCE
SOCIAL GROUPS
SEE ALSO HEALTH AND SCIENTIFIC ORGANIZATIONS
SEE ALSO PSYCHOLOGY SOCIAL, GROUP PROCESSES
SEE ALSO SOCIOECONOMICS, INCOME, LOW INCOME GROUPS
ROIHL 19869 03 Antecedents of adolescent hypertension
(human)
ROIHL 2229802 Oiigins ol hypertension (human)
SOCIAL GROUPS, ETHNIC
SEE ALSO ENVIRONMENT, ECOLOGY HUMAN
SEE ALSO SOCIOLOGY AND ANTHROPOLOGY OTHER, CULTURE
POIHL 1310809 0009 Clinical heart tiansplantation B
cell alloantigens in caidiac allogiatt compatibility (human)
ROIHL 19859 03 Epidemiological studies, piecuisois of
hypertension (human)
ROIHL 1986403 0003 Blood pressure ol children and
young adults Heart rate and blood pressure -Consistency
in infancy (human)
ROIHL 1986903 Antecedents ol adolescent hypertension
(human)
ROIHL 1987003 Hypertensive piogeny Physical and
humoial piecuisoi seaich
R01HL19929-03 High blood pressure in the young.
prevalence and piecuisois (human)
ROIHL 20471 03 Atheioscleiosis and diabetes mellitus
(human) j j „
R23HL2191701 Adrenal steioids in adolescent and adult
hypertension
SOCIAL GROUPS, ETHNIC, AMERICAN INDIANS
** ROlHL-21039-02 Vasculai lesions of diabetes in Oklahoma
Indians
SOCIAL GROUPS, ETHNIC, AMERICANS, BLACK
AMERICANS
ROIHL 1845603 Cardiovasculai follow-up of hypertensive
adolescents
** R01HL187 15-02 Hypertension incidence pio)ect (human)
ROlHL-19956-03 High blood pressure in the young
(human)
ROIHL 20655-02 Autonomic piedictois of hypertension in
children
P60HL-20985-01 0005 Northein Calitoinia sickle cell
centei - Molecular mechanism of alpha thalassemia-
Relation to sickle cell anemia (human)
ROlHL-21352-02 Community studies of obstiuctive lung
disease (human)
ROlHL-22032-01 Caidiovascular events in hypertensives
(human)
R01HL-22739-01 Evolution and progression of pediatiic
atheioscleiosis
" ROlHL-23201-01 Mechanisms of hypertension (human,
lats)
SOCIAL GROUPS, ETHNIC, AMERICANS,
HAWAIIANS
ROlHL-16774-04 Genetic epidemiology of hypertipemia
(Honolulu)
SOCIAL GROUPS, ETHNIC, AMERICANS,
JAPANESE-AMERICANS
ROlHL-16774-04 Genetic epidemiology of hyperlipemia
(Honolulu)
SOCIAL GROUPS, ETHNIC, AMERICANS,
MEXICAN -AMERICANS
R01HL-20005-03 Factors in blood pressure levels of
children
ROlHL-20655-02 Autonomic predictois of hypertension in
children
SOCIAL GROUPS, ETHNIC, AMERICANS, WHITE
AMERICANS
ROlHL-18456-03 Cardiovascular follow-up of hypertensive
adolescents
R01HL19956-03 High blood pressure in the young
(human)
ROlHL-20655-02 Autonomic predictois ol hypertension in
children
ROlHL-21352-02 Community studies of obstructive lung
disease (human)
ROlHL-23194-02 Genetics of hypertension and associated
vaiiables (human)
** ROlHL-23201-01 Mechanisms of hypertension (human,
lats)
SOCIAL GROUPS, ETHNIC, ASIANS, JAPANESE
" NOlHV-62955-04 Data collection in clinical pathology and
moibid anatomy (men)
SOCIAL GROUPS, ETHNIC, POLYNESIANS
** R01HL20159-03 Genetic epidemiology of precursois of
hypertension (human)
soc
SOCIAL GROUPS, MINORITY GROUPS
POIHI 09011 15 0018 A if.eiiich and i«»ouic« piogum
in blood Hepatitis B in noimal populations Epidemiology,
ink factois and lunjmniion
SOCIAL GROUPS, RACIAL STOCKS
POIHI 089/4 14 0028 Naluial and e«peiim«nt»l
atheioscleiosis Geogiaphic pathology ol alheiojcleiosii
and coionaiy heart disease (human)
ROIHI 167/4 04 Genetic epidemiology of hypeilipemia
(Honolulu)
SOCIAL GROUPS, RACIAL STOCKS, BLACK RACE
SEE ALSO SOCIAL GROUPS. ETHNIC. AMERICANS. BLACK
AMERICANS
POIHL 08974 14 0005 Natuial and expeiimental
atheioscleiosis Atheioscleiosis. coronary heart disease
and sudden death (human)
ROIHL 2000503 Factors in blood pressure levels of
children
ROIHL 20034 03 Hypertension Psychophysiologic and
genetic precursors (human)
ROIHL 20535 02 Cardiovascular disease and evolving
diabetes mellitus (human)
P01HL-20993 02 0003 Population dynamics of arterial
cells in atherogenesis Clonal phenomena in atherogenesis
(human, hares)
ROIHL 23194 02 Genetics of hypertension and associated
variables (human)
NOIHV 22938 11 Therapy for hypertension in general
population
SOCIAL GROUPS, RACIAL STOCKS, WHITE RACE
POIHL 08974 14 0005 Natural and experimental
atherosclerosis Atherosclerosis, coronary heart disease
and sudden death (human)
ROlHL-20005-03 Factois in blood pressure levels of
children
ROIHL 20034-03 Hypertension-Psychophysiologic and
genetic precursois (human)
R01HL-2053502 Cardiovascular disease and evolving
diabetes mellitus (human)
ROlHL-22032-01 Cardiovascular events in hypertensives
(human)
SOCIAL GROUPS, RELIGIOUS, SEVENTH DAY
ADVENTISTS
ROlHL-20005-03 Factors in blood pressure levels of
children
SOCIAL ISOLATION-DEPRIVATION
SEE PSYCHOSOCIAL ISOLATION-DEPRIVATION
SOCIAL PSYCHOLOGY
SEE PSYCHOLOGY SOCIAL (SEE ALSO SOCIAL.)
SOCIAL SERVICE PSYCHIATRIC
SEE MENTAL HEALTH SERVICES. SOCIAL SERVICE
PSYCHOSOCIAL
SOCIAL SERVICE PSYCHOSOCIAL
SEE MENTAL HEALTH SERVICES, SOCIAL SERVICE
PSYCHOSOCIAL
SOCIAL SERVICES (GENERAL)
SEE ALSO HEALTH AND SCIENTIFIC ORGANIZATIONS,
VOLUNTARY HEALTH ORGANIZATIONS
SEE ALSO HEALTH ECONOMICS, FUND RAISING
SEE ALSO MENTAL HEALTH SERVICES, SOCIAL SERVICE
PSYCHOSOCIAL
P60HL- 15 169-05 0021 Support for centei for sickle cell
disease ■ Multidisciplinaiy module system foi education,
screening and counseling
P60HL-15170-05 0023 Support foi centei foi sickle cell
anemia - Comprehensive sickle cell clinic
P60HL15996-06 0008 Cincinnati comprehensive sickle
cell center - Patient care (children, adults)
P60HL16005-05 0001 Comprehensive sickle cell center -
Demonstration -Community service component
P60HL-16008-06 0001 Wayne State University
comprehensive sickle cell center - Patient care system
(children, adults)
P60HL16008-06 0011 Wayne State Univeisity
comprehensive sickle cell center - Education, screening and
counseling
P60HL-20985-01 0008 Northern California sickle cell
center - Demonstration community program -Patient
ambudsman
SOCIAL WORK PSYCHIATRIC
SEE MENTAL HEALTH SERVICES, SOCIAL SERVICE
PSYCHOSOCIAL
SOCIETIES, HEALTH AND SCIENTIFIC
SEE HEALTH AND SCIENTIFIC ORGANIZATIONS
SOCIOCULTURE
SEE SOCIOLOGY AND ANTHROPOLOGY OTHER, CULTURE
SOCIOECONOMIC FACTORS IN HYPERTENSION
SEE CARDIOVASCULAR DISORDERS, HYPERTENSION
(SYSTEMIC), ENVIRONMENT-ASSOCIATED
SOCIOECONOMICS
SEE ALSO HEALTH ECONOMICS
SEE ALSO HEALTH INSURANCE
(contd)
•Excludes routine methodology OR covers only general projects which preclude
••Oriented significantly to above subied.
indexing at the specific level.
tt Giant has subproiects describing specific research aspects.
See Appendix foi investigatois name and giant number
Origins of hypertension (human)
Self-management systems tor asthmatic
soc
SEE ALSO OCCUPATIONS
POlHL-08974-14 0005 Natural and experimental
atherosclerosis Atherosclerosis, coronary heart disease
and sudden death (human)
P01HL0901115 0018 A research and resource program
in blood - Hepatitis B in normal populations -Epidemiology,
risk factors and transmission
ROlHL-14378-07 Lipemias and reconstructive cardiac
surgery (human)
R01HL15174-06 CV disease epidemiology-Second
generation studies (human)
ROlHL-19858-03 UMMC-Blood pressure precursors and
consequences (human)
ROlHL-19864-03 0003 Blood pressure of children and
young adults - Heart rate and blood pressure-Consistency
in infancy (human)
ROlHL-19869-03 Antecedents of adolescent hypertension
(human)
ROlHL-1987003 Hypertensive progeny-Physical and
humoral precursor search
ROIHL 19962-03 High blood pressure in young people in
Tecumseh
ROlHL-22298-02
NOlHR-72974-01
children
SOCIOECONOMICS, FINANCING ORGANIZED
SEE ALSO HEALTH ECONOMICS, HEALTH CARE COSTS-
FINANCING
SEE ALSO HEALTH ECONOMICS, HEALTH CARE COSTS-
FINANCING, MEDICAL INDIGENCY
SEE ALSO HEALTH INSURANCE
POlHL-1131012 9004 Mechanisms of cardiovascular
disease • Core support-computer facilities
SOCIOECONOMICS, FINANCING ORGANIZED,
INCOME INSURANCE
P60HL15996-06 0009 Cincinnati comprehensive sickle
cell center - Insurance coverage of persons with sickle cell
trait and disease
SOCIOECONOMICS, INCOME, LOW INCOME
GROUPS
SEE ALSO HEALTH ECONOMICS, HEALTH CARE COSTS-
FINANCING, MEDICAL INDIGENCY
SEE ALSO SOCIOENVIRONMENT, URBAN POVERTY AREAS
P50HL-14153-07 0001 Johns Hopkins Lung Center-
Chronic diseases of airways ■ Genetic and environmental
factors in chronic pulmonary disease (human)
SOCIOECONOMICS, SOCIAL CLASS
SEE ALSO SOCIOECONOMICS, INCOME, LOW INCOME GROUPS
R01HL16774-04 Genetic epidemiology of hyperlipemia
(Honolulu)
ROlHL-22021-01 Asthma in families - Behavior analysis of
family interaction pattern
SOCIOENVIRONMENT
SEE ALSO ENVIRONMENT, ECOLOGY HUMAN
SEE ALSO FAMILY
SEE ALSO PSYCHOSOCIAL ISOLATION-DEPRIVATION
POlHL-08974-14 0028 Natural and experimental
atherosclerosis - Geographic pathology of atherosclerosis
and coronary heart disease (human)
ROlHL-15174-06 CV disease epidemiology-Second
generation studies (human)
R01HL18776-04 Prevention of acute and fatal
cardiovascular disease (human)
R01HL19839-09 Factors in youth predisposing to chronic
diseases (former college students)
ROlHL-1992203 Childhood determinants of blood pressure
ROIHL- 19929-03 High blood pressure in the young.
prevalence and precursors (human)
ROIHL 19930-03 A prospective study -Blood pressure in
High blood pressure in young people In
neviborn twins
ROlHL-19962-03
Tecumseh
ROlHL-19984-02 Blood pressure and immunogenetic
factors in the young (human)
ROlHL-20005-03 Factors in blood pressure levels of
children
ROlHL-22298-02 Origins of hypertension (human)
SOCIOENVIRONMENT, RESIDENCE
CHARACTERISTICS, HOUSING
P50HL-18318-03 0012 Pathogenesis and complications of
hypertension - Behavioral factors in hypertension (human)
ROlHL-19073-02 Heart disease and drinking water at
home
SOCIOENVIRONMENT, RESIDENTIAL MOBILITY
P50HL-1413607 0009 Pulmonary SCOR -Airways
obstructive diseases - Tuscon epidemiological study of
airways obstructive disease (human)
P50HL18318-03 0012 Pathogenesis and complications of
hypertension - Behavioral factors in hypertension (human)
SOCIOENVIRONMENT, RESIDENTIAL MOBILITY,
MIGRANTS
SEE ALSO POPUUTION STUDIES HUMAN
ROlHL-20159-03 Genetic epidemiology of precursors of
hypertension (human)
496
SOCIOENVIRONMENT, RURAL AREAS
P50HL-14153-07 0010 Johns Hopkins Lung Center-
Chronic diseases of airways - Risk factors for airways
obstruction in a rural community (human)
** P60HL-17292-04 0003 Vermont Lung Center - Subclinical
pulmonary disease in a rural environment (human)
" ROlHL-181 75-03
community
R01HL21352 02
Drug taking for hypertension in a rural
Community studies of obstructive lung
disease (human)
ROlHL-22802-01 A rural mining community hypertension
control project (human)
NOlHV-42902 08 Epidemiological studies of coronary heart
disease (human)
SOCIOENVIRONMENT, URBAN AREAS
ROlHL-187 15-02
ROlHL-21352-02
disease (human)
NOlHV-42902-08
disease (human)
Hypertension incidence project (human)
Community studies of obstructive lung
Epidemiological studies of coronary heart
SOCIOENVIRONMENT, URBAN POVERTY AREAS
P50HL-183 18-03 0012 Pathogenesis and complications of
hypertension - Behavioral factors in hypertension (human)
SOCIOLOGY AND ANTHROPOLOGY OTHER,
CULTURE
SEE ALSO SOCIAL GROUPS, ETHNIC
ROiHL-22298-02 Origins of hypertension (human)
SOD
SEE METALLOPROTEINS, CYTOCUPREINS
SODIUM
SEE ALSO BODY FLUID BALANCE, IONIC, HYPONATREMIA
SEE ALSO KIDNEY FUNCTION, SALURESIS
ROlHL-00340-29 Electrolyte disturbance in cardio-renal
disease (human, dogs, rats)
ROlHL-02334-23 Micropuncture study of kidney function
(rats, animals)
ROlHL-02493-22 Kidney function in experimental heart
failure (dogs, rats)
ROlHL-03303-21 Factors regulating electrolyte excretion by
the kidney (human, dogs)
POlHL-0628518 0198 Cardiovascular-respiratory
physiology and biochemistry - Renal tubular secretion of
hydrogen ion (animals)
POlHL-06312-17 0051 Surgical cardiology - Diuretic
therapy on myocardial electrolyte composition and water
content (human)
ROlHL-07835-17 Experimental hypertension and renal
circulation (rats, rabbits)
POlHL-07896-15 0049 Environmental biomedical research
program - Effects of hyperbaric oxygen and pressure on
cerebral enzymes (rats)
ROlHL-09364-14 Ion transport by heart mitochondria
(cattle, rat, rabbit)
R01HL10503-13 Cardiac ion transport and ultrastructure
(rats, guinea pigs, rabbits)
ROlHL-10612-13 0018 Humoral factors in heart failure
and hypertension - The pathogenesis of experimental renal
hypertension (dogs, rabbits, rats)
ROlHL-10612-13 0021 Humoral factors in heart failure
and hypertension - The control of aldosterone secretion
(dogs)
ROlHL-10942-09 Study of genetic hypertension in rats
POlHL-11351-12 0018 Cellular and molecular
mechanisms of myocardial function - Quantitative
localization of electrolytes in cardiac tissue
** POlHL-1 1678-11 0001 Cardiovascular dynamics and their
control - Body fluid volumes In the genesis of hypertension
(rats, dogs)
POlHL-11678-11 0046 Cardiovascular dynamics and their
control Regulation of aldosterone secretion and related
factors (dogs)
POlHL-1 1678-11 0047 Cardiovascular dynamics and their
control - Unidentified pituitary factor in regulation of
aldosterone secretion (rats)
POlHL-1 1678-11 0063 Cardiovascular dynamics and their
control - Renin-angiotensin system-Control of renal
hemodynamics, electrolyte excretion
POlHL-12157-11 0058 Functions and mechanisms of cell
membrane ion transport - Ionic and osmotic regulation in
toadfish -A euryhaline aglomerular teleost
POlHL-121 57-11 0060 Functions and mechanisms of cell
membrane ion transport - Ion transport and electrical
properties of giant-celled alga
POlHL-12738-10 0134 Physiologic pharmacology and its
clinical applications - Adenylate cyclase and cAMP
phosphodiesterase in cardiac development (dogs)
** ROlHL-12827-08 Regulation of sodium excretion (dogs,
rats)
" ROlHL-12879-09 0006 Pulmonary transport and
metabolism in vivo ■ The missing sodium
ROlHL-12879.09 0008 Pulmonary transport and
metabolism in vivo • Stop-flow technique for permeability
measurements
ROlHL-13237-09 Erythrocytes during early development
(human, animals)
ROlHL-13339-08 Pharmacology of developing cardiac
tissues (chick embryo)
Regulation of the circulation in
Kallikrein-kinin system in hypertension
•Excludes routine methodology OR covers only general projects which preclude indexing
"Oriented significanthf to above subject.
at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
SOD
ROlHL-13349-06 Analysis of activation process in heart
muscle (guinea pigs, rabbits, human)
ROlHL-13595-08 Renin and vascular hyper-reactivity in
hypertension (human, rats)
ROlHL-14133-08 Intrarenal regulation of sodium
reabsorption (dogs, hamsters, rats)
R01HL14148-07 0002 The regional circulations -
Catecholamine metabolism in subtypes of hypertension
(human, animals)
P50HL-14159-08 0008 Specialized center of research in
hypertension ■ Renal function and sodium metabolism in
hypertension (rats, human, rabbits)
P50HL 14159-08 0020 Specialized center of research in
hypertension - Renin-mineralocorticoid system in
hypertension (human, rat. dog)
** POlHL-14388-07 0157 Regulation of the circulation in
pathological states - Autoregulation of renal blood flow and
distribution in sodium excretion control
** P01HL14388-07 0210 Regulation of the circulation in
pathological states - Effects of dietary sodium on blood
pressure and vascular reactivity
** POlHL-14388-07 0223 Regulation of the circulation in
pathological states - Kallikrein-kinin system in hypertension
(rats)
** POlHL-14388-07 0224
pathological states -
(human)
POlHL-14414-07 0014 Environmental influences on
cardiorespiratory and cellular functions - Temperature and
acid-base status in tissues, cells, and subcellular system
R01HL14560-07 Hypertension produced by sympathetic
dysfunction (human, rats)
ROlHL-14944-07 Renal vascular reactivity in hypertensive
patient
ROlHL-15124-05 Genesis of hypertension in renal disease
(human, dogs)
POlHL-15835-06 0023 Study of muscles related to heart
disease - Cellular basis of the Frank-Starting curve (frogs,
rats)
R01HL-16010-16 Cellular basis of cardiac contractility
(frogs)
POlHL-1611705 0002 Ion movements and membranes in
cardiovascular control - Fluorescence and excitation-
contraction coupling in heart (frogs)
R01HL17749-03 Adrenocortical factors in human
hypertension (human)
ROlHL-17879-04 Molecular structure of the ouabain
sensitive ATPase (dogs)
R01HL18053-03 Intracellular ionic activities in heart
muscle (frogs)
** P50HL-1831803 0007 Pathogenesis and complications of
hypertension - Humoral factors and renal function in
experimental hypertension (rats)
P50HL-18318-03 0013 Pathogenesis and complications of
hypertension - Humoral factors and renal function in
human hypertension
P50HL-18318-03 0019 Pathogenesis and complications of
hypertension - Renin-angiotensin system in blood pressure
regulation (human, rat, dog)
P50HL-1832304 0011 SCOR hypertension center -
Endocrine profiling on a selected normal population
(human)
POlHL-18575-03 0002 Mechanisms of vascular changes
in hypertension - Endocrines. electrolytes, and
hemodynamics in hypertension (pigs)
P01HL18575-03 0005 Mechanisms of vascular changes
in hypertension - Renin synthesis in normotensive and
hypertensive pigs (also rats, dogs)
ROlHL-18730-03 Role of mineralocorticoids in low renin
hypertension (human, rats)
ROlHL-18875-03 Angiotension, prostaglandins, pressure
and the kidney (rats)
ROlHL-18882-02 Hormones in hypertension (human)
P50HL-19157-02 0001 Studies in cystic fibrosis and
bronchiolitis - Laboratory core unit
P50HL-19157-02 0007 Studies in cystic fibrosis and
bronchiolitis - Analysis of cystic fibrosis factors (human)
R01HL19229-02 Prostaglandins and hypertension (human,
rats, dogs, rabbits)
ROlHL-19287-03 The antihypertensive function of the
renal medulla (human, rats, rabbits)
R01HL-19320-03 Angiotensin neuropharmacology-
Relationship to sodium
" P50HL-19362-02 0012 A/S SCOR-Atherosclerosis in
nonhuman primates ■ Induction of chronic hypertension by
salt loading (baboon)
ROlHL-19653-03 Circulatory system effects of angiotensin
analogs (rats)
ROlHL-19673-03 Surgical aspects of shock and hypoxia
(dogs, monkeys, rats)
ROlHL-20711-01 Structure-function relationships in red
cell NA-K pumps (goats)
ROlHL-20720-02 Myocardial protection during
cardiopulmonary bypass (dogs)
ROlHL-2072502 Mechanisms and cellular functions of ion
transport
ROlHL-21030-01
(rats)
'* ROlHL-21092-02 Factors other than renin in renal
hypertension (rats)
R23HL-21196-02 Digitalis induced arrhythmia and NAO KO-
atpase activity (dogs)
(contd)
Calcium regulation and hypertension
STA
SOD
ROIHL 21210 01 Acul« rinil Ulluw lollowing csidiaf
jutgtry (humin)
R23HL 2121301 * model loc calcium homeoslasii m
encltibla tissut (nutma woims)
ROIHI 21371 02 Enefgy loss miccoaiulysis o( myocaidial
cations . . ,. , ,
ROIHI 21493 02 Conlraclility in cardiac tailuta (hamsteis)
ROIHI 2167301 Pathophysiology ol venous changes in
hypertension liats. labbits. human, dogs)
R01HL21849 02 Conliol ol sodium tiansport and cellulai
respiration (toad bladder)
ROIHL 21860 18 Factors inlluencing responses to
adrenergic drugs (guinea pigs. rats, cats)
•* ROIHL 22039 02 Ion transport in cardiac muscle (dogs,
rodents, cattle)
ROIHL 22S6902 Intestinal secretion Capillary and tissue
lorces (dogs, cats)
ROlHL-2283601 The spontaneously hypertensive kidney
(rats) _ ,
ROIHL 23392 01 Membrane binding and transport ol
calcium and potassium ionophores
SODIUM BICARBONATE
•• PbOHL 1918502 0007 Pulmonary SCOR Neonatal
respiratory distress syndromes Sodium bicarbonate and
albumin in resuscitation ol preterm infants (human)
SODIUM CHLORIDE
SEE ALSO NUTRITION. DIET THERAPEUTIC. SALT RESTRICTED
•• P01HL06285 18 0199 Cardiovascular-respiratory
physiology and biochemistry Renal tubular reabsorption ot
sodium chloride (hamsters, rabbits)
♦• PO1HL0628518 0200 Cardiovascular-respiratory
physiology and biochemistry - Medullary counter-current
system (animals)
*• ROlHL-09911-12 Hormonal and dietary modification of
NaCl toxicity (rats) mice)
POIHL U414-07 0014 Environmental influences on
cardiorespiratory and cellular functions - Temperature and
acid-base status in tissues, cells, and subcellular system
SODIUM NITROFERRICYANIDE (NITROPRUSSIDE)
SEE IRON CYANIDES. SODIUM NITROFERRICYANIDE
SODIUM PENTOTHAL
SEE PYRIMIDINES. BARBITURATES. THIOPENTAL
SODIUM-POTASSIUM PUMP
SEE BIOLOGICAL TRANSPORT. ACTIVE TRANSPORT. ION
PUMPS. SODIUM-POTASSIUM PUMP
SODIUM PUMP
SEE BIOLOGICAL TRANSPORT, ACTIVE TRANSPORT. ION
PUMPS, SODIUM PUMP
SODIUM SALICYLATE
SEE PHENYLCARBOXYUTES, SALICYLATES
SODIUM TRANSPORT DISORDERS, BARTTER'S
SYNDROME
SEE METABOLIC DISORDERS INBORN, BARHERS SYNDROME
SOUD STATE
SEE PHYSICAL PROPERTIES, SOLID STATE
SOLITARY TRACT NUCLEUS
SEE BRAIN, MEDULLA OBLONGATA. SOLITARY TRACT
NUCLEUS
SOLUBILITY
SEE PHYSICAL PROPERTIES, SOLUBILITY
SOLUBLE RIBONUCLEIC ACID
SEE NUCLEIC ACIDS, TRNA
SOLUTES
SEE PHYSICAL PROPERTIES, SOLUTES
SOLUTIONS
SEE PHYSICAL PROPERTIES, SOLUTIONS
SOLUTIONS (DOSAGE FORM)
SEE DOSAGE FORMS
SOLUTIONS ASSOCIATION
SEE PHYSICAL PROPERTIES, SOLUTIONS ASSOCIATION
SOLVATION ENERGIES
SEE BIOLOGICAL TRANSPORT, TRANSPORT ENERGETICS
SOLVENT FRACTIONATION
SEE PHYSICAL SEPARATION. FRACTIONATION, SOLVENT*
SOLVENTS
SEE PHYSICAL PROPERTIES, SOLVENTS
SOIVOLYSIS
SEE CHEMICAL REACTIONS, SOLVOLYSIS
SOMATIC AFFERENT NERVES
SEE NERVOUS SYSTEM, AFFERENT NERVES. SOMATIC
AFFERENT NERVES
SOMATIC ANTIGENS, NONMICROBIAl
SEE IMMUNOLOGY. ANTIGENS. SURFACE ANTIGENS
(GENERAL)
SOMATIC CELL GENETICS
SEE GENETICS. SOMATIC CELL AND TRANSFORMATION
•Excludes routine methodology OR covers only general proiects which preclude
••Oriented significantly to above subject
SOMATIC REFLEXES
Sll NfUROPHYSIOlOGY. RftLFX. SOMATIC REFLEXES
SOMATOLOGY (GENERAL)
Sft BODY PHYSICAl CHARACIf RISIICS (GENERAL)
SOMATOMAMMOTROPIN, CHORIONIC
SfL REPRODUCTIVE HORMONES, CHORIONIC
SOMAIOMAMMOIROPIN
SOMATOMEDIN
SEE GROWTH HORMONES VERTEBRATE. SOMATOMEDIN
(SULFATION FACTORXTHYMIDINE FACTOR)
SOMATOSENSORY MOTOR SYSTEM (GENERAL)
SEE NEUROMOTOR SYSTEM. SENSORIMOTOR SYSTEMS
(GENERAL)
SOMATOTROPIN
SEE PITUITARY DIENCEPHALON HORMONES. SOMATOTROPIN
SOUND
SEE PHYSICAL PROPERTIES. SOUND
SOUND FREQUENCY
SEE PHYSICAL PROPERTIES. SOUND FREQUENCY
SOUND MEASUREMENTS, HEART
SEE HEART DISORDERS DIAGNOSIS. HEART SOUND
MEASUREMENTS*
SOUND MEASUREMENTS, VASCULAR
SEE CARDIOVASCULAR DISORDERS DIAGNOSIS. SOUND
MEASUREMENTS. VASCULAR*
SOUTH AMERICA
SEE GEOGRAPHICAL SITES. S AMERICA
SPACE BIOLOGY, MEDICINE
SEE ENVIRONMENT. EXTRATERRESTRIAL. SUPRATERRESTRIAL
SPASMOLYTICS
SEE MUSCLE RELAXANTS. ANTISPASMODICS
SPECIAL (REMEDIAL) EDUCATION
SEE EDUCATION. SPECIAL (REMEDIAL)
SPECIES
SEE BIOLOGY. SYSTEMATIC. SPECIES
SPECIFIC GRAVITY
SEE PHYSICAL PROPERTIES. DENSITY (SPECIFIC GRAVITY)
SPECTRIN
SEE PROTEINS, MEMBRANE PROTEINS, SPECTRIN
SPECTROGRAPHY
SEE CHEMISTRY, ANALYTICAL METHODS, SPECTROMETRY*
SPECTROMETRY
SEE CHEMISTRY, ANALYTICAL METHODS, SPECTROMETRY*
SPECTROPHOTOFLUOROMETRY
SEE CHEMISTRY, ANALYTICAL METHODS,
SPECTROPHOTOFLUOROMETRY*
SPECTROPHOTOMETRY
SEE CHEMISTRY, ANALYTICAL METHODS, SPECTROMETRY*
SPECTROSCOPY
SEE CHEMISTRY, ANALYTICAL METHODS, SPECTROMETRY*
SPECTROSCOPY, FOURIER TRANSFORM
SEE OPTICS, INTERFEROMETRY*
SPECTROSONOGRAPHY (HEART)
SEE HEART DISORDERS DIAGNOSIS, HEART SOUND
MEASUREMENTS*
SPERMATOZOA
SEE FERTILITY, SPERM (ALL STAGES)
SPERMIDINE
SEE AMINES, SPERMIDINE
SPERMINE
SEE AMINES, SPERMINE
SPHEROCYTOSIS HEREDITARY
SEE BLOOD AND RE DISORDERS, ANEMIA HEMOLYTIC
CONGENITAL, SPHEROCYTOSIS HEREDITARY (GENERAL)
SPHEROIDAL CELL CARCINOMA (CARCINOID)
SEE NEOPLASMS OF NERVOUS SYSTEM. CARCINOID
SPHINGOLIPIDS, CERAMIDE
ROlHL-17462-03 Role of glycosphingolipids in platelet
aggregation (rats, human, dogs)
SPHINGOMYELINS
SEE PHOSPHOLIPIDS. PHOSPHOSPHINGOUPIDS.
SPHINGOMYELINS
SPIDER BITES AND VENOMS
SEE TOXICOLOGY. ANIMAL POISONS. ARTHROPOD. SPIDER
SPIDER MONKEY
SEE MAMMALS, PRIMATES. MONKEYS AND APES
(ANTHROPOIDS, NON-HUMAN). NEW WORLD MONKEYS
(PLATYRHINES)*
SPIKE POTENTIAL
S[( (KCIROPOIfNIIAlS, SPIM PGIFNtlAl
SPINAL CORD
Ml NFRVOUS SYSTEM CENTRAl. SPINAL CORD
SPINAL CORD LESIONS SURGICAL
SE( NfUROSURGERY. SPINAl CORD LESIONS SURGICAL
SPINAL CORD MAPPING
SEE NERVOUS SYSTEM CFNIRAl. SPINAL CORD MAPPING
SPINAL FLUID
SEE NERVOUS SYSTEM CENTRAL. CEREBROSPINAL FLUID
SPINAL INJURIES
SEE INJURIES. BACK. SPINAL
SPINAL NERVES
SEE NERVOUS SYSTEM. SPINAL NERVES
SPINAL REFLEXES
SEE NEUROPHYSIOLOGY, REFLEX. SPINAL REFLEXES
SPIROMETRY
SEE RESPIRATORY DISORDERS DIAGNOSIS. SPIROMETRY
SPIRONOLACTONE
SEE STEROIDS SPIROLACTONES. SPIRONOLACTONE
SPLANCHNIC NERVES
SEE NERVOUS SYSTEM AUTONOMIC. SPLANCHNIC NERVES
SPLEEN
SEE BLOOD AND RE SYSTEM. SPLEEN
SPLEEN TISSUE (CELLS) TRANSPLANTATION
SEE BLOOD AND RE SYSTEM. SPLEEN TISSUE (CELLS)
TRANSPUNTATION
SPLENECTOMY
SEE BLOOD AND RE SYSTEM. SPLENECTOMY
SPLENIC ARTERY
SEE CARDIOVASCULAR SYSTEM. ARTERIES. SPLENIC ARTERY
SPLENIC DISORDERS
SEE BLOOD AND RE DISORDERS. SPLENIC DISORDERS
SPLENOMEGALY
SEE BLOOD AND RE DISORDERS. SPLENIC DISORDERS.
SPLENOMEGALY
SPLENORENAL SHUNT FOR VENOUS BYPASS OF
LIVER
SEE LIVER CIRCULATION, VENOUS BYPASS OF LIVER
SPONTANEOUS HYPERTENSIVE RATS
SEE MAMMALS, RODENTS, MYOMORPHA, SPONTANEOUS
HYPERTENSIVE RATS*
SPREADING FACTOR
SEE CARBOHYDRASES, HYALURONIOASE
SPREADING FACTOR (HYALURONATE LYASE)
SEE POLYSACCHARIDE CO LYASES. HYLURONATE LYASE
SPUTUM
SEE BODY FLUIDS, SPUTUM
SQUALENE
SEE TERRENES, SQUALENE
SQUIRREL MONKEYS
SEE MAMMALS, PRIMATES, MONKEYS AND APES
(ANTHROPOIDS, NON-HUMAN), NEW WORLD MONKEYS
(PLATYRHINES)*
SRNA
SEE NUCLEIC ACIDS, TRNA
SRS
SEE SLOW REACTING SUBSTANCES
STABILE COMPONENT
SEE BLOOD COAGUUTION, FACTOR VII
STABILE FACTOR
SEE BLOOD COAGULATION, FACTOR VII
STABILITY, CHEMICAL
SEE CHEMICAL STABILITY
STABLE CARBON LABELED
SEE ISOTOPE LABELED, STABLE CARBON
STABLE ISOTOPE EFFECTS
SEE ISOTOPE EFFECTS (EXCLUDING RADIATION EFFECTS)
STABLE (LABELED) ISOTOPE DIAGNOSIS
SEE RADIOISOTOPE (NUCLEAR) MEDICINE, STABLE (LABELED)
ISOTOPE DIAGNOSIS
STAGING, NEOPLASMS
SEE NEOPLASMS CUSSIFICATION AND STAGING
STANDARDIZATION
SEE BIOLOGICAL PREPARATIONS AND STANDARDIZATION
SEE DRUG QUALITY-STANDARDS
SEE TISSUE (CELL) CULTURE, CELL CULTURE COLLECTIONS
BANKS AND REGISTRIES
(contd)
indexing at the specificlevel.
M Grant has subproiects describing specific research aspects.
See Appendix for investigator's name and grant number.
STA
STANDARDS, DIAGNOSTIC
SEE DIAGNOSTIC QUALITYSTANOARDS
STANDARDS FOR HEALTH CARE QUALITY
SEE HEALTH CARE QUALITY
STANDARDS FOR INFORMATION GATHERING
METHODS (GENERAL)
SEE INFORMATION GATHERING METHODS EVALUATION-
STANDARDS
STANNOUS FLUORIDE
SEE HALOGENS, FLUORINE (COMPOUNDS) SEE ALSO
SPECIFICS
STANOLONE
SEE ANDROSTANE SERIES, ANDROSTANOLONE
STAPHYLOCOCCAL INFECTIONS
SEE BACTERIAL DISEASES, STAPHYLOCOCCAL INFECTIONS
STAPHYLOCOCCUS
SEE BACTERIA, MICROCOCCACEAE, STAPHYLOCOCCUS*
STAPHYLOCOCCUS AUREUS
SEE BACTERIA, MICROCOCCACEAE, STAPHYLOCOCCUS
AUREUS*
STAPHYLOCOCCUS EPIDERMIDIS
SEE BACTERIA, MICROCOCCACEAE, STAPHYLOCOCCUS
EPIDERMIDIS*
STARVATION
SEE NUTRITIONAL ABNORMALITIES, STARVATION
STATISTICAL MODELS
SEE MODELS. MATHEMATICAL
STATISTICAL SERVICE AND CENTERS
SEE ALSO COMPUTER CENTERS
** P50HL-14164-07 0039 A/S SCOR -Comparative and
experimental atherosclerosis - Statistical resource and
research management unit
STATISTICS
SEE MATHEMATICS, STATISTICS (INCLUDING BIOMETRY)
SEE NEOPLASTIC DISEASE EPIDEMIOLOGY-STATISTICS
STEARIC ACID
SEE FATTY ACIDS, STEARIC ACID
N-STEAROYL-O-LACTOSYLSPHINGOSINE
SEE GLYCOSPHINGOLIPIDS, CERAMIDE DIHEXOSIDES
N-STEAROYLSPH INGOSINE
SEE SPHINGOLIPIDS, CERAMIDE
STEATORRHEA, CONGENITAL PANCREATIC
SEE METABOLIC DISORDERS INBORN, CYSTIC FIBROSIS
STEINERT'S DISEASE
SEE METABOLIC DISORDERS INBORN, MYOTONIA ATROPHICA
STEM CELLS, HEMATOPOIETIC
SEE BLOOD CELLS, HEMATOPOIETIC STEM CELLS (GENERAL)
STEREOCHEMISTRY
SEE CHEMICAL STRUCTURE, STEREOCHEMISTRY
STEREOISOMERS
SEE CHEMICAL STRUCTURE, ISOMERS, STEREOISOMERS
(GENERAL)
STEREOPHOTOG RAPH Y
SEE OPTICS, PHOTOGRAPHY, STEREOPHOTOGRAPHY*
STEREOTAXIC TECHNIQUE
R01HL-ie315-05 Analysis of interaction between CNS
vasomotor systems (cats, rats)
STERILITY
SEE FERTILITY
STEROID AGLYCONES
SEE STEROIDS GLYCOSIDES AGLYCONES
STEROID GLYCOSIDES
SEE STEROIDS GLYCOSIDES
STEROID HORMONES
SEE ENDOCRINOLOGY, HORMONES, STEROID HORMONES
STEROID HORMONES BIOSYNTHESIS
SEE ENDOCRINOLOGY, HORMONES BIOSYNTHESIS, STEROID
HORMONES BIOSYNTHESIS
STEROID HYDROXYLASES (GENERAL)
SEE OXYGENASES, STEROID MONOOXYGENASES (GENERAL)
STEROID METABOLISM
SEE ALSO STEROIDOGENESIS
** ROlHL-02033-23 Regulation of cholesterol esters in blood
and tissues (rat, cattle, human)
** ROlHL-03299-21 Dietary effects on cholesterol metabolism
(rats, rabbits)
ROlHL-05062-18 Lipid metabolism in cultured cells
(human, rats, rabbits)
R01HL-05209-I8 Lipid metabolism (monkeys)
M ROlHL-06222-18 Clinical and laboratory studies in lipid
metabolism (human, mammals, non-human)
498
R01HL-06481-1S Lipid metabolism (human, rats)
* POlHL-06835-17 0020 Cardiovascular disease - Lipid
metabolism (rats)
ROlHL-09744-14 Experimental vascular sclerosis
(monkeys, rabbits)
* ROIHL 10894-12 Intestinal bacteria and steroid
metabolism (human, guinea pigs, rabbits, rats)
ROlHL-1093313 Fat metabolism and atherosclerosis
(rabbits, cattle, human, rats)
ROlHL-1 1901-12 0004 Effects of metabolic surgery on
the hyperlipidemias - Ileal bypass -Cholesterol dynamics
studies (rats, rabbits, dogs)
ROlHL-12399-13 Specific fatty acids and cholesterol
metabolism (gerbils, rats)
ROlHL-12740-10 Hypocholesterolemic agents -
Stereochemistry (rats)
POlHL-13262-07 0016 Arterial wall in atherosclerosis -
Lipids in elastin preparations from atherosclerotic plaques
(human, animals)
ROlHL-13405-09 Regulation of lipid metabolism in the
lung (rats)
P50HL-14164-07 0029 A/S SCOR -Comparative and
experimental atherosclerosis - Development of pigeon
substrains
» P50HL-14 164-07 0033 A/S SCOR -Comparative and
experimental atherosclerosis - Comparative studies of
lipoprotein distribution and metabolism (monkeys)
P50HL-14164-07 0035 A/S SCOR-Comparative and
experimental atherosclerosis ■ Lipid metabolism -Interaction
with arterial metabolism (monkey, pigeon)
P50HL- 14 164-07 0036 A/S SCOR-Comparative and
experimental atherosclerosis Connective tissue
metabolism-Interaction with arterial metabolism (monkeys)
' P50HL-14164-07 0037 A/S SCOR-Comparative and
experimental atherosclerosis - Genetic control of plasma
cholesterol-Interaction of dietary fatty acid (monkey)
P50HL-14197-07 Support for center of research on
arteriosclerosis
P50HL-14197-07 0006 Support for center of research on
arteriosclerosis - Diets and drugs affecting lipid
metabolism (human)
P50HL-14197-07 0007 Support for center of research on
arteriosclerosis - Metabolic defects in familial
hyperlipoproteinemias (human)
P50HL-14230-07 0092 A/S SCOR-Lipids, atherosclerosis
and thrombosis ■ Tissue lipids -Cell culture studies
(human)
' P50HL-14236-05 0001 Prevention of premature
arteriosclerosis - Metabolism and transport of cholesterol
and vitamin A (human, rats)
P50HL-14236-06 0009 Prevention of premature
arteriosclerosis ■ Clinical studies on cholesterol metabolism
(human)
ROlHL-143 13-07 Apoproteins of triglyceride rich
lipoproteins (human, squirrel monkeys, rats)
ROlHL-1 5263-06 Lecithin -Cholesterol acetyltransferase
(human, rabbits)
ROlHL-15448-06 Surgical and metabolic aspects of
venous grafts, (dogs, monkeys, rabbits)
ROlHL-15504-05 Animal model for studies on averting
atherosclerosis (swine)
ROlHL-15646-03 Lipid studies in vascular smooth muscle
cells (human, monkeys)
ROlHL-15797-05 Lipid metabolism and atherosclerosis in
primates (monkeys, human, squirrels)
ROlHL-15895-05 In vitro study of lipoproteins in vascular
disease (human, animals)
R01HL-16364-04 Regulation of lipid biosynthesis and
transport (rats, swine. Xenopus)
ROlHL-17371-05 Regualtion of cholesteryl ester levels in
the aorta (swine)
ROlHL-17564-03 Unsaturated fats-Mode of
hypocholesterolemic action (minipig)
ROlHL-18157-04 Subcellular events in atherosclerosis
(human, rabbits, calves)
P50HL-183 18-03 0015 Pathogenesis and complications of
hypertension - Cultured smooth muscle cells and
microvessel metabolism (mammals)
POlHL-18574-03 Lipoprotein methodology and biomedical
applications
POlHL-18574-03 0004 Lipoprotein methodology and
biomedical applications - Fine structure and metabolism of
lipoproteins-EM studies (guinea pigs)
R01HL-18682-03 Protein kinase and cholesterol
metabolism in aorta (rabbits)
ROlHL-18687-03 Pathophysiology of genetic
hypertriglycerinemias (human)
P50HL-19362-D2 0001 A/S SCOR-Atherosclerosis in
nonhuman primates - Effects of infant nutrition on
atherosclerosis (baboons)
P50HL-19362-02 0003 A/S SCOR-Atherosclerosis in
nonhuman primates - Heritability of characters related to
atherosclerosis (baboons)
P50HL-19362-02 0005 A/S SCOR-Atherosclerosis in
nonhuman primates - Hybridization to produce primate
model of atherosclerosis (baboon. Rhesus)
P50HL-19362-02 0009 A/S SCOR-Atherosclerosis in
nonhuman primates • Cholesterol metabolism and
intestinal microflora (baboon)
P50HL-19362-02 0013 A/S SCOR-Atherosclerosis in
nonhuman primates - Core laboratory-Lipid biochemistry
(baboons)
'Excludes niutine methodotogy OR covers only general projects which preclude indexing at the specific level.
"OiiMitad significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
STE
ROlHL-20183-02 Portacaval shunt as treatment for
hyperlipemia (pigs)
ROIHL 20418-03 Serum cholesterol binding reserve in
diabetes (human)
** ROlHL-20483-03 Sterol balance and cholesterol absorption
in diabetics (human)
** ROlHL-20488-03 Cholesterol metabolism in diabetic man
M P50HL-2 1006-02 Specialized center of research in
arteriosclerosis
" P50HL-2100602 0002 Specialized center of research in
arteriosclerosis - Turnover and metabolism of cholesterol in
man
R01HL-2359801 Dietary fat, cholesterol and bile acid
turnover (rats)
STEROID METABOLISM DISORDERS INBORN
SEE ADRENAL GUNDS DISORDERS, HYPERALDOSTERONISM
STEROID MONOOXYGENASES (GENERAL)
SEE OXYGENASES, STEROID MONOOXYGENASES (GENERAL)
STEROID SULFATES
SEE STEROIDS SULFATES
STEROIDOGENESIS
R01HL-02033 23 Regulation of cholesterol esters In blood
and tissues (rat, cattle, human)
R01HL-02477-23 Biosynthesis and function of lipids
(microorganisms, rats)
ROIHL 05360 19 Cholesterol biosynthesis and its control
in liver (rats)
POlHL-06835-17 0020 Cardiovascular disease - Lipid
metabolism (rats)
POlHL-06835-17 0032 Cardiovascular disease - Synthesis
of angiotensin II as inhibitors for aldosterone
POlHL-06835-17 0055 Cardiovascular disease - Vascular
and adrenocortical response to angiotensin II (dogs)
POlHL-06835-17 0056 Cardiovascular disease -
Angiotensin analogs-Sarcosine on arterial pressure,
aldosterone (dogs)
ROIHL 06975-18 Pathogenesis and prevention of
hypertension (rats)
** ROlHL-08634-15 Enzymic cholesterol synthesis (human,
rats, protozoa, yeast)
ROlHL-11901 12 0004 Effects of metabolic surgery on
the hyperlipidemias - Ileal bypass -Cholesterol dynamics
studies (rats, rabbits, dogs)
ROIHL-11901-12 0015 Effects of metabolic surgery on
the hyperlipidemias Portacaval shunt for cholesterol
reduction (dogs, rabbits)
ROlHL-12740-10 Hypocholesterolemic agents-
Stereochemistry (rats)
** P50HL-14164-07 0037 A/S SCOR-Comparative and
experimental atherosclerosis - Genetic control of plasma
cholesterol-Interaction of dietary fatty acid (monkey)
P50HL-14230-07 0093 A/S SCOR-Lipids, atherosclerosis
and thrombosis - Clinical studies involving cellular lipid
content (human)
P50HL-14236-05 0009 Prevention of premature
arteriosclerosis - Clinical studies on cholesterol metabolism
(human)
ROlHL-14313-07 Apoproteins of triglyceride rich
lipoproteins (human, squirrel monkeys, rats)
** ROlHL-15476-05 Mechanism and control of sterol
biosynthesis (rats)
ROlHL-15930-06 Hormonal control of lipid and lipoprotein
synthesis (rats)
** ROlHL-16294-04 Effectors of cholesterol synthesis (rats)
ROlHL-16364-04 Regulation of lipid biosynthesis and
transport (rats, swine, Xenopus)
ROIHL 17458-04 Renal control of sodium excretion (rats)
ROlHL-17749-03 Adrenocortical factors in human
hypertension (human)
ROIHL- 178 18-05 Metabolism of cholesterol and cholesterol
in man (also rats, monkeys)
ROlHL-17882-04 Regulation of HMG-COA reductase and
sterol synthesis (human, mammals)
ROlHL-18553-03 Membrane defects in familial
hypercholesteremia (human)
R01HL-19063-03 Cholesterol and lipoprotein metabolism
(rat hepatocytes)
ROlHL-19223-03 Control of cholesterogenesis in leukocytes
and liver (rats, human)
ROlHL-20183-02 Portacaval shunt as treatment for
hyperlipemia (pigs)
ROlHL-20488-03 Cholesterol metabolism in diabetic man
R23HL-2 1066-02 Angiotensin and prostaglandin control of
aldosterone (rats)
ROlHL-22990-01 Angiotensin II receptors-Mechanisms of
regulation (rats)
STEROIDS
SEE ALSO BILE ACIOS AND SALTS
SEE ALSO CHOLANATE SERIES
SEE ALSO ENDOCRINOLOGY, HORMONES, STEROID
HORMONES
SEE ALSO STEROLS
ROlHL-08399-15 Platelet injury in infections and allergic
diseases (human)
** R01HL12557-09 Effects of steroids and pregnancy on
arteries and veins (guinea pigs)
ROlHL-13466-08 Pulmonary platelets in shock, trauma
and embolization (dogs, pigs, rats)
(contd)
STE
ROIHL 1361909 Microsomal «i«ctioii tmnspoil in livei
and heart (human, mammals)
POIHI 14388 0/ 0219 Regulation ot the circulation in
patholoiical states Myocaidial ischemia and inlafction in
animals (dogs)
ROIHL 14692 06 Alpha I antitiypsin deficiency and
pulmonary disease (human)
POIHL 1498b0; OOOb Adaptation to hypoxia Control
mechanisms in the pulmonary microcirculation (animals)
•• ROIHL 16651 05 Evaluation o1 steroid therapy in
sarcoidosis (human)
POIHL 16?69 05 0008 Pathobiologic and host defense
reactions in the lung Pulmonary immunocytologic defense
mechanisms- against bacteria (human, animals)
ROIHL 16916 04 0001 The role of albumins in lung water
accumulation Capillary permeability (dogs, human)
ROIHL 1691604 0011 The role of albumins in lung water
accumulation Whole body distribution and exchange of
albumin (rabbits, human, monkeys)
•* ROIHL 1691805 Role of steroids in hypertension (human)
P60HL 17269 04 0016 National heart and blood vessel
research and demonstration center New analytical
methodology for atherosclerosis studies
POIHL 17813 04 0001 Lung disease and the oxygenation
ot blood and tissue Diffuse interstitial lung disease ■
Pathophysiology (human, dogs)
** ROIHL 17909 04 Drug treatment of vascular scleroprotein
defects (human, turkeys)
ROIHL 19077-01 Biochemistry and molecular biology of
sarcoidosis (human, rabbits)
P50HL-19153-02 0003 SCOR-Pulmonary edemas-Titology.
pathogenesis Possible inhibitors of mediator release and
pulmonary vascular response (sheep)
R23HL19573 01 Studies on pulmonary serotonin (mice)
ROIHL 20783 02 Airway reactivity-Badrenoceptors and
prostaglandins (guinea pigs)
** POIHL 20993-02 0008 Population dynamics of arterial
cells in atherogencsis Angiotoxicity of cholesterol
oxidation in atherogenesis (rabbits)
ROlHL-21922-01 Transient currents induced by
strophanthidin in the heart
POlHL-2261901 0010 Cellular mechanisms of heart
failure - Mitochondria in heart and smooth muscle (rabbits,
rats, dogs)
ROlHL-22883-01 Lung epithelial cell interactions in vitro
STEROIDS, HYDROXYSTEROIDS
SEE ALSO STEROLS
ROlHL-20176-02 Biochemistry and genetics of salt
hypertension (rats)
STEROIDS ANALOGS
SEE ALSO CHOLESTANE SERIES, CHOLESTEROL ANALOGS
ROlHL-2145701 C(17)side group geometry and
cardenolide activity (cats, guinea pigs)
STEROIDS GLYCOSIDES
SEE ALSO CARDIAC GLYCOSIDES
R01HL16549-04 Cardiotonic steroid-NaK ATPase
interactions (cattle)
STEROIDS GLYCOSIDES AGLYCONES
ROlHL-16549-04 Cardiotonic steroid-NaK ATPase
interactions (cattle)
*• ROlHL-18118-04 Total synthesis of cardiac aglycones
STEROIDS SPIROLACTONES, SPIRONOLACTONE
ROlHL-00759-29 Regulation of electrolyte and acid base
equilibrium (dogs)
POlHL-06835-17 0045 Cardiovascular disease - Pressure-
volume-renin relationship in human hypertension
" POlHL-06835-17 0047 Cardiovascular disease -
Spironolactone in primary aldosteroidism (human)
POlHL-06835-17 0049 Cardiovascular disease - Selective
hypoaldosteronism (human)
ROlHL-1104612 Renin, angiotensin, steroids, ions and
blood pressure (human, sheep, rabbits)
POlHL-11414-11 0014 Thrombosis and atherosclerosis
program - Role of adrenal in human essential hypertension
POlHL-1 1678-11 0065 Cardiovascular dynamics and their
control - Body fluid volumes in the genesis of hypertension
(dogs) ,
P50HL-14192-08 0007 Specialized center of research in
hypertension - Role of new mineralocorticoids in
hypertension (human, rats)
POlHL-14388-07 0190 Regulation of the circulation in
pathological states - fVlechanisms of the renal actions of
aldosterone (rats)
ROlHL-1 7458-04 Renal control of sodium excretion (rats)
R01HL17749-03 Adrenocortical factors in human
hypertension (human)
P50HL-18323-04 0037 SCOR hypertension center ■
Adrenocortical factors in childhood hypertension
ROlHL-18730-03 Role of mineralocorticoids in low renin
hypertension (human, rats)
ROlHL-19428-03 Role of angiotensin sensitivity in renin
release (human)
ROlHL-21996-01 Alteration of digitalis and aldosterone
disposition (rats, rabbits, mice, dogs)
ROlHL-22482-01 Circulatory hemodynamics and sodium
excretion (dogs)
4V9
STEROIDS SULFATES
ROIHI WfllSO'j Metabolism of cholesterol and cholesterol
in man (also i.its. mnnkl!y^)
STEROL-ESTER HYDROLASE
Sff ESTERASES. CHOIESIEROL ESTERASE
STEROLS
SEE ALSO BILE ALCOHOLS
SEE ALSO STEROIDS
ROIHL 02477 23 Biosynthesis and function of lipids
(microorganisms, rats)
•• ROIHL 07878 16 Metabolism of neutral sterols (rats,
rabbits)
ROIHL 08634 15 En^mic cholesterol synthesis (human,
rats, protozoa, yeast)
•• P01HL08974 14 0024 Natural and experimental
atherosclerosis Atherosclerosis, sterol and lipoprotein
metabolism in nonhuman primates
ROIHL 10160 13 Origins of atherosclerosis (human)
ROIHL 12745 10 Enzymes and inhibitors of cholesterol
biosynthesis (rats, human, swine)
P50HL 1423605 0009 Prevention of premature
arteriosclerosis Clinical studies on cholesterol metabolism
(human) . , >
*• ROIHL 15376 06 Intermediary metabolism of sterols (mice)
*• ROIHL 15476 05 Mechanism and control of sterol
biosynthesis (rats)
ROIHL 15646 03 Lipid studies in vascular smooth muscle
cells (human, monkeys)
R01HL1666006 Phospholipid-cholesterol and
phospholipidprotein interactions
ROIHL 17882 04 Regulation of HMG-COA reductase and
sterol synthesis (human, mammals)
ROIHL 18610-03 Early intervention of age related arterial
changes (pigeon)
*• ROlHL-20483-03 Sterol balance and cholesterol absorption
in diabetics (human)
M P01HL-20948-02 Molecular basis of cholesterol
metabolism
•• POIHL 20948 02 0001 Molecular basis of cholesterol
metabolism - Biochemical and ultrastructural
characterization of LDL in human fibroblasts
POlHL-2094802 0002 Molecular basis of cholesterol
metabolism - LDL pathway in cell lines with informative
properties other than fibroblasts
POlHL-20948-02 0004 Molecular basis of cholesterol
metabolism - Genetic analysis of the LDL pathway (human)
•* POlHL-2099302 0008 Population dynamics of arterial
cells in atherogenesis • Angiotoxicity of cholesterol
oxidation in atherogenesis (rabbits)
ROlHL-2124602 Roles of cholesterol and its metabolic
regulation (CHJ cell mutants)
•* R01HL-2253201 Inhibitors of cholesterol biosynthesis
(rats. mice, yeast)
** ROlHL-22570-01 Interactions of sterols in biological
systems (human)
** POlHL-22633-01 0002 Cellular and molecular biology ot
lipoprotein metabolism • Sterol metabolism in tissue
culture cells
** POlHL-2263301 0003 Cellular and molecular biology ot
lipoprotein metabolism ■ Sterol metabolism in platelets and
megakaryocytes (human, rabbits, guinea pigs)
STEROLS ESTERS
ROlHL-10160-13 Origins of atherosclerosis (human)
ROIHL- 1 78 18-05 Metabolism of cholesterol and cholesterol
in man (also rats, monkeys)
STILBENES, CLOMIPHENE
ROlHL-03941-18 Uterine blood flow and changes in
pregnancy (sheep)
STILBENES, DIETHYLSTILBESTROL
ROlHL-02965-22 Metabolism of plasma lipoproteins (rats,
chickens, human)
STILBESTROL
SEE STILBENES, DIETHYLSTILBESTROL
STILLBIRTH
SEE PREGNANCY LOSS. FETAL DEATH
STIMULANTS, GANGLIONIC
SEE NEUROPHARMACOLOGICAL AGENTS. GANGLIONIC
STIMUUTING AGENTS
STIMULANTS, GROWTH
SEE GROWTH FACTORS (INCL. ANABOLICS)
STIMULANTS, MUSCLE
SEE MUSCLE STIMULANTS
STIMULANTS, PSYCHIC
SEE PSYCHOPHARMACOLOGICAL AGENTS. ANTIDEPRESSANTS
STIMULATION, CHEMICAL
SEE DRUGS. PHARMACOLOGY. STIMUUTION, CHEMICAL
STIMULUS-RESPONSE (GENERAL)
SEE ALSO ELECTROPOTENTIALS, EVOKED POTENTIALS
SEE ALSO ELECTROSTIMULUS
SEE ALSO EYE, VISUAL STIMULUS
SEE ALSO TEMPERATURE, HEAT, CALORIC STIMUUTION
STR
POIHI 1215/ II 00% funtlioni and mechaniim* of call
membiane ion lian\port Iwtopic (lu«t m \ynlh«ttt
%tiands ol heart celli (chick embryo)
POIHI 12157 11 005/ functions and mechanum* of cell
membrane ion transport Electrophysiological
investigations of synthetic strands of heart muscles (i»l«)
ROIHI 1/689 06 Neuiophysiologic tludits of ie»pi(iloiy
control (cats)
** ROIHL 1//2904 Stimulus response coupling in platelets
(human)
STOICHIOMETRY
SEE CHEMISTRY, STOICHIOMETRY
STOKES-ADAMS DISEASE
SEE HEART DISORDERS, ARRHYTHMIA. HEART BLOCK.
STOKES ADAMS SYNDROME
STOMACH ULCER
SEE GASTROINTESTINAL DISORDERS. PEPTIC ULCER
STOP FLOW TECHNIQUE
SEE PHYSICAL PROPERTIES. FLOWMETERS. STOP FLOW
TECHNIQUE-
STORAGE DISORDERS
SEE METABOLIC DISORDERS INBORN. LYSOSOMAL
DISORDERS
STRATUM CORNEUM (EPIDERMIS)
SEE SKIN (GENERAL)
STREPTOCOCCACEAE
SEE BACTERIA, STREPTOCOCCACEAE"
STREPTOCOCCAL INFECTIONS
SEE BACTERIAL DISEASES, STREPTOCOCCAL INFECTIONS
STREPTOCOCCUS
SEE BACTERIA, STREPTOCOCCACEAE, STREPTOCOCCUS-
STREPTOCOCCUS AGALACTIAE
SEE BACTERIA, STREPTOCOCCACEAE, STREPTOCOCCUS
GROUP B*
STREPTOCOCCUS GROUP A
SEE BACTERIA, STREPTOCOCCACEAE, STREPTOCOCCUS
GROUP A*
STREPTOCOCCUS GROUP B
SEE BACTERIA, STREPTOCOCCACEAE, STREPTOCOCCUS
GROUP B*
STREPTOCOCCUS GROUP C
SEE BACTERIA, STREPTOCOCCACEAE, STREPTOCOCCUS
GROUP C*
STREPTOCOCCUS GROUP D
SEE BACTERIA, STREPTOCOCCACEAE, STREPTOCOCCUS,
ENTEROCOCCUS GROUP*
STREPTOCOCCUS HEMOLYTICUS (S.PYOGENES)
SEE BACTERIA, STREPTOCOCCACEAE, STREPTOCOCCUS
GROUP A*
STREPTOCOCCUS PNEUMONIAE
SEE BACTERIA, STREPTOCOCCACEAE, STREPTOCOCCUS
PNEUIi/lONIAE*
STREPTOCOCCUS PYOGENES (S. HEMOLYTICUS)
SEE BACTERIA, STREPTOCOCCACEAE, STREPTOCOCCUS
GROUP A*
STREPTOKINASE
SEE IMMUNOLOGY. ANTIGENS BACTERIAL, STREPTOKINASE
STRESS BIOLOGICAL, PHYSIOLOGICAL
SEE ENVIRONMENT, STRESS
STRESS MECHANICAL
SEE ENVIRONMENT, STRESS MECHANICAL
STRESS, MUSCLE
SEE MUSCLE FUNCTION, MUSCLE STRESS
STRESS, PRENATAL
SEE PREGNANCY, PRENATAL STRESS
STRESS PSYCHOLOGIC
SEE PSYCHOLOGIC STRESS
STRETCH RECEPTORS
SEE MUSCLE FUNCTION. MUSCLE STRETCH (RECEPTORS)
SEE RESPIRATORY SYSTEM, PULMONARY STRETCH
RECEPTORS
STRETCH REFLEX
SEE MUSCLE FUNCTION, MUSCLE STRETCH REFLEX
STRIATED MUSCLE
SEE MUSCLES, STRIATED MUSCLE
STROKE
SEE CEREBROVASCUUR DISORDERS, STROKE
STROPHANTHIDIN
SEE CARDIAC GLYCOSIDES AGLYCONES, STROPHANTHIDIN
STROPHANTHIN G
SEE CARDIAC GLYCOSIDES, OUABAIN
(contd)
•Excludes routine methodology OR covers only general projects which preclude
••Oriented significantly to atwve subject.
indexing at the specificlevel.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
STR
STRUCTURAL CHEMISTRY
SEE CHEMICAL STRUCTURE
STRUCTURAL GENE
SEE GENETICS, GENES, OPERON. STRUCTURAL GENE
STRUCTURE OF CARBOHYDRATES
SEE CARBOHYDRATES STRUCTURE
STRUCTURE OF LIPIDS
SEE LIPIDS STRUCTURE
STRUCTURE OF NUCLEIC ACIDS
SEE NUCLEIC ACIDS STRUCTURE
STRUCTURE OF PROTEINS-PEPTIDES
SEE PROTEINS-PEPTIDES STRUCTURE
STUART FACTOR
SEE BLOOD COAGULATION. FACTOR X
STUDENTS, HEALTH OCCUPATIONS
SEE EDUCATION. HEALTH OCCUPATIONS
STYRENE POLYMERS
SEE RUSTICS, STYRENE POLYMERS
SU-488S
SEE PYRIDINES, METYRAPONE
SUBARACHNOID SPACE
SEE NERVOUS SYSTEM CENTRAL. MENINGES. SUBARACHNOID
SPACE
SUBCORTICAL STRUCTURES
SEE BRAIN. SUBCORTICAL STRUCTURES
SUBMANDIBULAR GLAND
SEE ORALPHARYNGEAL. SALIVARY GLANDS, SUBMANDIBULAR
SUBMAXILLARY GLAND
SEE ORALPHARYNGEAL, SALIVARY GLANDS, SUBMANDIBUUR
SUBSTITUTION REACTIONS (CHEMISTRY)
SEE CHEMICAL REACTIONS, SUBSTITUTION
SUBSTITUTION TRANSFUSION
SEE BLOOD TRANSFUSION, EXCHANGE
SUCCESS-FAILURE
SEE PSYCHOLOGY, PERFORMANCE, SUCCESS-FAILURE
SUCCINATE:(ACCEPTOR) OXIDOREDUCTASE
SEE OXIDOREDUCTASES, SUCCINATE (ACCEPTOR)
OXIDOREDUCTASE
SUCCINIC ACID
SEE DICARBOXYLIC ACIDS, SUCCINIC ACID
SUCROSE
SEE OISACCHARIOES, SUCROSE
SUDDEN DEATH, HEART DISORDERS
SEE HEART DISORDERS, SUDDEN DEATH
SUDDEN INFANT DEATH SYNDROME
SEE CHILDREN. INFANT AND CHILD MORTALITY, SUDDEN
INFANT DEATH SYNDROME
SUFFOCATION, ACCIDENTAL
SEE INJURIES, ACCIDENTS, SUFFOCATION
SUGAR ACIDS, HEXURONIC ACIDS,
GLUCURONIC ACID
ROlHL-21763-09 Heparin and heparan sulfate-Structure
and activity (beef, hog)
SUGAR ACIDS, HEXURONIC ACIDS, L-IDURONIC
ACID
ROlHL-21763-09 Heparin and heparan sulfate-Structure
and activity (beef, hoe)
SUGAR ACIDS, SIALIC ACIDS
POlHL-09011-15 O0C5 A research and resource program
in blood Characterization of hepatitis-B antigen and the
cause of serum hepatitis (human)
POlHL-1 1351-12 0004 Cellular and molecular
mechanisms of myocardial function - Molecular
mechanisms of contractile function and differentiation
(animals)
POlHL-11351-12 0009 Cellular and molecular
mechanisms of myocardial function - Myocardial membrane
surface coat (rats, rabbits)
ROIHL 14692-06 Alpha I antitrypsin deficiency and
pulmonary disease (human)
R01HL-1482007 Factors affecting physiology of biological
membranes (human)
ROlHL-15125-07 Molecular pathology of genetic disorders
in man
ROlHL-1572806 The carbohydrate of the blood-clotting
glycoproteins (mammals)
P50HL-19190-02 0005 Pulmonary SCOR -Pathophysiology,
management of IRDS - Glycoproteins in mucous secretions
(human, cattle)
R01HL-20092-02 Structural and biological properties of
fibrinogen (human, rabbits)
500
SUGAR ACIDS, URONiC ACIDS
SEE ALSO SUGAR ACIDS, HEXURONIC ACIDS, GLUCURONIC
ACID
R01HL-18593-03 Characterization of heart valve collagen
(human, pig)
SUGAR ALCOHOLS, HEXITOLS, INOSITOL
SEE ALSO PHOSPHOLIPIDS. PHOSPHOGLYCERIDES,
PHOSPHOINOSITIDES
ROlHL-0579118 Structure and function in hemoglobins
(human)
** ROlHL-12399-13 Specific fatty acids and cholesterol
metabolism (gerbils, rats)
SUGAR ALCOHOLS, HEXITOLS, INOSITOL
PHOSPHATES
R01HL-05791-18 Structure and function in hemoglobins
(human)
ROlHL-06950-17 Red cell metabolism (human,
vertebrates)
P60HL 1599905 0021 Miami comprehensive sickle cell
center - Diphosphonates -Erythrocyte calcium loading,
maturation (human, chick embryo)
** ROlHL-18082-03 Erythrocyte phosphates and vertebrate
gas transport (amphibians, reptiles)
SUGAR ALCOHOLS, HEXITOLS, ISOSORBIDE
DINITRATE
R01HL2271801 Cardiovascular drug interactions-
Metabolism models (dogs)
SUGAR ALCOHOLS, HEXITOLS, MANNITOL
ROlHL-05875-18 Pathologic metabolic and physiologic
studies of heart (human, dogs, cats)
POlHL-0628518 0143 Cardiovascular-respiratory
physiology and biochemistry - Myocardial ischemia (human.
dogs, lambs)
M P01HL06664-17 Cardiopulmonary function in remediable
vascular disease
** POIHL-0666417 0010 Cardiopulmonary function in
remediable vascular disease - Ischemia and acute renal
failure (rats)
** POlHL-0666417 0034 Cardiopulmonary function in
remediable vascular disease Role of hyperosmolar agents
in ischemic heart disease (dogs)
** POlHL-06664-17 0036 Cardiopulmonary function in
remediable vascular disease - In vitro studies on the
mechanism of ischemic damage to cells (rabbits)
POIHL 1131012 0063 Mechanisms of cardiovascular
disease ■ Myocardial function, metabolism and cellular
integrity after heart surgery (dogs)
ROlHL-1253010 Emphysema-Respiratory function in
disease (human, dogs, rats)
Regulation of sodium excretion (dogs.
Fetal hearts in organ culture (mice)
Autoregulation of glomerular filtration
R01HL-I2827-08
rats)
ROlHL-14706-07
ROlHL-14914-06
rate (rats)
*♦ ROIHL 15522-06 Influence of mannitol on ischemia
cardiac muscle (dogs, cats, rats)
R01HL-1665606 Left ventricular function in exercise
(dogs)
R01HL-17458-04 Renal control of sodium excretion (rats)
P50HL17669-04 0006 Ischemic heart disease center
(SCOR) - Studies of hypoxic, acidotic and ischemic cardiac
muscle (dogs)
ROIHL 18024-03 Regional myocardial flow and function
relationships (dogs)
R01HL-18204-03 Regional blood flow in viral myocarditis
(turkeys)
ROlHL-18606-04 Pathogenesis and measurement of
pulmonary edema (human, rabbits, dogs)
ROIHL-19030-03 Tissue protection during circulatory
interruption (dogs)
ROlHL-20080-02 Surgically induced myocardial edema
(dogs)
ROlHL-2028302 Maintenance of cellular integrity in
ischemic hearts (cats)
ROlHL-20352-02 Defenses of lung cells against oxygen
toxicity (human, animals)
** ROlHL-221 72-01 Hypotension, renal ischemia and effect of
mannitol (dogs, rats)
POlHL-226 19-01 0010 Cellular mechanisms of heart
failure - Mitochondria in heart and smooth muscle (rabbits,
rats, dogs)
SUGAR NUCLEOTIDES
R23HL-22818-01 Biosynthesis of human respiratory
mucous glycoprotein (also dog)
SUGAR SEQUENCE
SEE CARBOHYDRATES STRUCTURE, SUGAR SEQUENCE
SUGAR TRANSPORT
SEE CARBOHYDRATES TRANSPORT (GENERAL)
SUGGESTION
SEE PSYCHOLOGY, SUGGESTION
SULFANILAMIDES, FURSEMIDE
R01HL-02493-22 Kidney function in experimental heart
failure (dogs, rats)
SUL
POlHL-1 1678-11 0065 Cardiovascular dynamics and their
control • Body fluid volumes in the genesis of hypertension
(dogs)
POlHL-14388-07 0191 Regulation of the circulation in
pathological states - Regulation of chloride transport in
epithelial membranes (turtles)
** POlHL-14388-07 0225 Regulation of the circulation in
pathological states - Release of renal prostaglandins by
saluretic-diuretic agents (dogs)
P50HL-18323 04 0043 SCOR hypertension center -
Pharmacology -Renin-aldosterone mechanisms in essential
hypertension (human)
ROlHL-22390-01 Effect of chloride on renin (rats, dogs)
** R23HL-22882-01 Modulation by disease of effect of
furosemide in man
** ROlHL-22911-01 Mechanism of clearance of lung edema
fluid (dogs)
SULFANILAMIDES, SALICYLAZOSULFAPYRIDINE
ROlHL-2199601 Alteration of digitalis and aldosterone
disposition (rats, rabbits, mice, dogs)
SULFATES
SEE ALSO CARBOHYDRATES. SULFOSUGARS
SEE ALSO STEROIDS SULFATES
** R01HL-09906-13 0024 Membrane transport processes in
red blood cells - Inhibition of sulfate transport in human
RBCs by isothiocyanic acid esters
ROIHL 17995-04 Cellular synthesis and release of
mucopolysaccharides (rabbits)
ROlHL-19746-03 Proliferation and differentiation of
alveolar macrophages (mice, hamsters)
SULFATION FACTOR
SEE GROVnn HORMONES VERTEBRATE. SOMATOMEDIN
(SULFATION FACTOR)(THYMIDINE FACTOR)
SULFHYDRYLS
SEE ALSO THIOLS
ROlHL-05883-18 0001 Reflex control of resistance and
capacitance vessels - Naturally occurring vasoactive
substances and the vascular neuroeffectors (dog)
ROIHL 09544-12 Biochemistry of contractile proteins
(animals)
POlHL-11310 12 0106 Mechanisms of cardiovascular
disease ■ Biochemical characterization of the collagens in
vascular tissue (catte)
POlHL-12157-11 0051 Functions and mechanisms of cell
membrane ion transport - Electron transport in the red cell
membrane (human, guinea pigs)
ROlHL-12994-09 The Rh complex of red cells (human)
ROlHL-14680-07 Specific enrichment of myoglobins for
carbon 13 NMR (catacea)
ROlHL-15498-06 Effects of physical training on lieart
(rats)
POlHL-1559605 0012 Coagulation, fibrinolysis,
hemostasis and hepatitis - Platelet function -Phorbol ester
and zymosan-induced release activity
R01HL15592-07 Force and speed in skeletal and cardiac
muscle
ROlHL-16674-05 Airborne metals and lung permeability
(bullfrogs, rats)
P01HL16833-04 0001 Hemoglobin and red cell system in
hemoglobinopathies ■ Motility, association and ligand
binding in hemoglobin -Hydrogen exchange
•* POlHL-16833-04 0017 Hemoglobin and red cell system in
hemoglobinopathies - Sulfhydryl group blockade antisickling
effect (human)
ROlHL-17930-03 Platelet membrane function-Assessment
and application (animals)
ROlHL-18185-04 Cardiac glycosides and diuretics-Role of
NaO pump (dogs)
ROlHL-18304-03 R-infrared spectroscopy of heart muscle
energetics (cattle)
ROlHL-1932303 Studies of platelet microtubule protein
P01HL-20984-02 0002 Cellular mechanisms in cardiac
hypertrophy - Thermodynamic, fluorescence, chemical
modification of hypertrophied heart myosin
POlHL-21016-02 0011 Sickle cell anemia and other
hemoglobinopathies - Metabolic effects of antisickling
agents (hamsters)
ROlHL-2246101 Cardiac tropomyosin and tropomyosin-
action interactions (rabbit)
ROlHL-22780-01 Factors modifying the reaction properties
of HgS (human)
ROlHL-22845-01 Response of cardiac myosin to
hypertrophic stress (rabbits)
ROlHL-22924-01 The airway mucosal barrier (guinea pigs)
Biochemical properties of human cardiac
ROlHL-23994-01
myosin
R01HL-24021-02
activity (human)
Erythocyte membrane sulfhydrls and Rh
•Excludes routine mettiodotogy OR covers only general projects which preclude indexing at the specific level.
"Oriented significantly to above subject
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
SULFHYDRYLS INHIBITORS
R01HL-13029-09 Metabolic regulation of sugar transport
(pigeons, rats)
P01HL-16251-06 0003 Membrane-bound enzymes in heart
and other tissues - Regulation of cardiac succinate
dehydrogenase (yeasts, mammals)
SULFIDES, DISULFIDES
SEE ALSO AMINO SULFIDES, CYSTAMINE
SEE ALSO CHEMICAL BONDS. DISULFIDE BONDS
(contd)
SUL
POIHI 18!i7603 0002 Thrombosis research prouram
ptoject Moleculat bisis o< fibrin formation (human, cattle,
lamprey)
ROIHI 19323 03 Studies of platelet microtubule protein
ROIHI 20184 02 Oesensili/atlon ot tracheal muscle to
isoproterenol (rats, rabbits)
SULFINES
SEE SULFONIUM COMPOUNDS
SULFINPYRAZONE
SEE PYRA20LIDINEOIONES. SULFINPYRAZONE
SULFITES, BISULFITES
ROIHL 18554 03 Taurine metabolism in mammalian heart
(rodents, cattle, swine)
SULFOBROMPHTHALEIN
SEE BENZOFURANONES. PHTHALIDES. BROMSULPHTHALEIN
SULFOMUCOPOLYSACCHARIDES
SEE POLYSACCHARIDES. GLYCOSAMINOGLYCANS,
SULFOMUCOPOLYSACCHARIDES
SULFONAMIDES
ROIHL 1796304
Human erythrocyte carbonic anhydrase
SULFONAMIDES, ACETAZOLAMIDE
R01HL00340-29 Electrolyte disturbance in cardio-renal
disease (human, dogs, rats)
R01HL00759 29 Regulation ot electrolyte and acid base
equilibrium (dogs)
R01HL14102-07 Human physiology at 5360 meters-
Mountain environment
POlHL-14985-07 0002 Adaptation to hypoxia ■ Oxygen
transport in man at high altitude
P01HL1498507 0009 Adaptation to hypoxia • Influence
of chemosensitivity on control of breathing during sleep
(human, dogs)
P01HL14985-07 0014 Adaptation to hypoxia ■ High
altitude pulmonary edema (human, rats, dogs)
POlHL-19737-02 0011 Cellular and molecular aspects of
respiratory physiology - Chemical and metabolic factors on
peripheral chemoreceptor activity (cats)
ROlHL-2225801 New aspects of pharmacology related to
carbonic anhydrase
SULFONAMIDES, CHLOROTHIAZIDE
P01HL06835-17 0049 Cardiovascular disease • Selective
hypoaldosteronism (human)
R01HL10711-12 Cooperative study of treatment of
hypertension (human)
ROlHL-12827-08 Regulation of sodium excretion (dogs.
rats)
ROlHL-15047-06 Digital computer analysis of the
electrocardiogram (human)
P01HL17871-04 0009 Kidney, sodium, cardiac output.
arterioles and hypertension • Kidney, sodium, cardiac
output, arterioles and hypertension
P50HL19362-02 0010 A/S SCOR-Atherosclerosis in
nonhuman primates ■ Antihypertensive therapy-
Atherogenesis in experimental hypertension (baboon)
ROlHL-20455-03 Role of systemic hypertension on diabetic
retinopathy (human)
ROlHL-22032-01 Cardiovascular events in hypertensives
(human)
ROlHL-22718-01 Cardiovascular drug interactions -
Metabolism models (dogs)
SULFONAMIDES, PHENYLSULFONAMIDES,
CHLORTHALIDONE
P50HL18323-04 0043 SCOR hypertension center -
Pharmacology-Renin-aldosteronc mechanisms in essential
hypertensien (human)
SULFONAMIDES, PROBENECID
R23HL-22882-01 Modulation by disease of effect of
furosemide in man
SULFONATES
SEE ALSO AMINOSULFONIC ACIDS
SEE ALSO PHENYLALKYLAMINES. BENZYLAMINES. BRETYLIUM
TOSYUTE
ROlHL-1 1822-10 Biophysical studies of macromolecular
interactions (microorganism, human)
ROlHL-18554-03 Taurine metabolism in mammalian heart
(rodents, cattle, swine)
SULFONATES, TRIMETHAPHAN CAMSYLATE
POlHL-11310-12 0058 Mechanisms of cardiovascular
disease - Dynamic response to vasodilating agents
postoperatively (human)
POlHL-11310-12 0065 Mechanisms of cardiovascular
disease - Algorithms for arterial pressure by automatic
vasoactive agents control (human)
ROlHL-2360201 Physiology of renin, aldosterone and
prostaglandin (human, rats, dogs)
SULFONES, DAPSONE
POlHL-1273810 0001 Physiologic pharmacology and its
clinical applications - Clinical pharmacology of cardioactive
drugs (human)
SULFONIUM COMPOUNDS
ROlHL-15104-07 A mechanism for oxidative
phosphorylation
SOI
4,4'-SULFONYlDIANILINE
SET SULFONFS, DAPSONI
SULFONYLUREA, TOLBUTAMIDE
ROIHI 09914 13 The myocardium in diabetes maliitus
(dogs, monkeys)
ROIHL 15698 12 Factors affecting the action ot
anticoagulants (rats, human)
SULFOPOLYSACCHARIDES
SEE POLYSACCHARIDES. SULFOPOLYSACCHARIDES
SULFOSUGARS
SEE CARBOHYDRATES, SULFOSUGARS
SULFOXIDES, DIMETHYL SULFOXIDE
P01HL03174 23 0011 Mechanisms of acute vascular
reaction to injury Mutagen metabolism by artery wall in
etiology of atherosclerosis (human, animals)
POlHL-06312 17 0033 Surgical cardiology Studies in
cryopreservations (rats)
ROIHL 12879 09 0010 Pulmonary transport and
metabolism in vivo Lung morphometry in control and
edematous lungs (dogs)
POIHL 16117-05 0005 Ion movements and membranes in
cardiovascular control Properties of isolated cell
membranes (rabbits, cats)
ROIHL 20219-02 Cryopreservation of the isolated heart
(rats)
SULFUR (COMPOUNDS) --SEE ALSO THI...
ROlHL-15640-06 Thermodynamic studies on model oxygen
carriers
POIHL 16251-06 0008 Membrane-bound enzymes in heart
and other tissues Iron sulfur centers and phospholipids
modulation of succinate dehydrogenase
SULFUR AMINO ACIDS, CYSTEINE
SEE ALSO PEPTIDES. GLUTATHIONE
POlHL-1 13 10-12 0106 Mechanisms of cardiovascular
disease - Biochemical characterization of the collagens in
vascular tissue (catte)
ROlHL-12972-09 Glutathione deficiency in red cells
(sheep, dogs)
ROlHL-163 18-21 Biochemistry and pharmacology of Na-K
transport
SULFUR AMINO ACIDS, ETHIONINE
POlHL-090 11-15 0021 A research and resource program
in blood - Regulation of transfer RNA methylating enzymes
(rats. E coli)
SULFUR AMINO ACIDS, HOMOCYSTINE
R01HL05062-18 Lipid metabolism in cultured cells
(human, rats, rabbits)
ROlHL-22623-01 Polyamines cellular mediators of
atherogenesis (human)
SULFUR AMINO ACIDS, METHIONINE
SEE ALSO NUCLEOSIDYL AMINO ACIDS, S-
ADENOSYLM ETHIONINE
POlHL-18577-03 0004 Lipoproteins-Cell surface
interactions - Analysis and chemical modification of
proteins in lipid transport (human, dogs)
SULFUR AMINO ACIDS, METHIONINE,
SELENOMETHIONINE
R01HL12085-10 Lipoprotein-carbohydrate metabolism
(human, rats)
SULFUR AMINO ACIDS, PENICILLAMINE
** P01HL1326207 0012 Arterial wall in atherosclerosis -
Characterization of connective tissue components (animals)
P50HL-15061-07 0004 Response of lung to injury ■
Biochemical abnormalities in connective tissues (rats)
ROlHL-16437-05 Drug treatment of atherosclerosis
(rabbits, monkeys)
SULFUR DIOXIDE
SEE SULFUR OXIDES
SULFUR OXIDES
ROlHL-15980-06 Reactions of hemeproteins and oxygen
(cattle)
P50HL-19170-02 0003 Harvard pulmonary SCOR -Chronic
diseases of the airways - Mechanisms of bronchial
reactivity to acute and chronic airway challenge (dog)
ROlHL-19746-03 Proliferation and differentiation of
alveolar macrophages (mice, hamsters)
SUN ORIENTATION
SEE ENVIRONMENT, ORIENTATION
SUNSTROKE
SEE INJURIES. TEMPERATURE DEPENDENT. HEAT INDUCED
SUPEROXIDE DISMUTASE
SEE METALLOPROTEINS. CYTOCUPREINS
SUPPLIED TISSUES
SEE TISSUE RESOURCES, REGISTRIES
SUPPORTING FRAMES FOR TISSUE GROWTH
SEE BIOMATERIALS, TISSUE SUPPORTING FRAMES
SUPPOSITORIES
SEE DOSAGE FORMS
SUPPRESSOR T LYMPHOCYTES
StI BIOOD cms. I lYMPHOi.YlfS. SUPPRf'.',OR
SURFACE ACTIVE AGENTS
Sit PHYSICAI PROPIRIIFS, SURIACIANI';
SURFACE ACTIVITY, CELLULAR
SFf MtMBHANI SURFACE (BIOLOGICAL) AtllVIIY (CfNERAL)
SURFACE ANTIGENS
SEE IMMUNOIOGY, ANTIGENS. SURFACE ANTIGENS
(GENERA!)
SURFACE ENZYMES
SEE ENZYMES. EXOENZYMES
SURFACE PROPERTIES (GENERAL)
SEE PHYSICAL PROPERTIES, SURFACE PROPERTIES
(GENERAL)
SURFACTANT, PULMONARY
SEE RESPIRATORY SYSTEM, PULMONARY SURFACTANT
SURFACTANTS
SEE PHYSICAL PROPERTIES, SURFACTANTS
SURGERY
SEE ALSO ADRENALECTOMY
SEE ALSO BLOOD AND RE SYSTEM, SPLENECTOMY
SEE ALSO BLOOD AND RE SYSTEM. THYMECTOMY
SEE ALSO CARDIOVASCULAR SURGERY
SEE ALSO CEREBROVASCULAR SURGERY
SEE ALSO EYE SURGERY
SEE ALSO GASTROINTESTINAL SURGERY
SEE ALSO HEART SURGERY
SEE ALSO KIDNEY SURGERY
SEE ALSO NEOPLASMS SURGERY
SEE ALSO NEUROSURGERY
SEE ALSO ORAL SURGERY
SEE ALSO PARATHYROIDECTOMY
SEE ALSO PITUITARY REMOVAL
SEE ALSO PREGNANCY. EMBRYO-FETUS SURGERY
SEE ALSO PROSTHESIS
SEE ALSO RESPIRATORY SYSTEM SURGERY
SEE ALSO SKELETAL DISORDERS. ORTHOPEDICS
SEE ALSO SKELETAL DISORDERS. ORTHOPEDICS. HIP
SURGERY
SEE ALSO STEREOTAXIC TECHNIQUE
SEE ALSO TEMPERATURE (BODY), HYPOTHERMIA INDUCED,
CRYOSURGERY
SEE ALSO TISSUE COMPATIBILITYTRANSPUNT.
TRANSPLANTATION
SEE ALSO URINARY TRACT SURGERY
** ROlHL-19255-03 Evaluation of diagnostic clinical
hemorrheology (human)
SURGERY, POSTOPERATIVE
SEE ALSO DISEASES. COMPLICATIONS, POSTOPERATIVE
POlHL-06312-17 0013 Surgical cardiology - Aortocoronary
vein bypass grafting (human)
POlHL-06312-17 0015 Surgical cardiology ■ Internal
mammary artery versus saphenous vein for coronary artery
bypass (human)
POlHL-06312-17 0016 Surgical cardiology - Effect of
hydralazine on infarct size following coronary occlusion
(human)
POlHL-06312-17 0053 Surgical cardiology - Enzyme
pattern following cardiac surgery (human)
POlHL-06835-17 0049 Cardiovascular disease - Selective
hypoaldosteronism (human)
P01HL11310-12 0054 Mechanisms of cardiovascular
disease - Mathematical model of ventricular pressure-
volume (human, dogs)
POlHL-1 1310-12 0055 Mechanisms of cardiovascular
disease - Ventricular pressure-volume after intracardiac
surgery (human)
POlHL-11310-12 0056 Mechanisms of cardiovascular
disease - Cardiac output response to blood pressure
reduction in infants (human)
POlHL-11310-12 0057 Mechanisms of cardiovascular
disease - Blood pressure reduction after heart surgery in
adults (human)
" POlHL-11310-12 0058 Mechanisms of cardiovascular
disease - Dynamic response to vasodilating agents
postoperatively (human)
POlHL-1 1310-12 0059 Mechanisms of cardiovascular
disease ■ Contractility-Acute response to diogoxin after
heart surgery (children)
** POlHL-11310-12 0062 Mechanisms of cardiovascular
disease - Myocardial depressant factor in postoperative
cardiac dysfunction (human, dogs)
** POlHL-11310-12 0063 Mechanisms of cardiovascular
disease - Myocardial function, metabolism and cellular
integrity after heart surgery (dogs)
POlHL-11310-12 0065 Mechanisms ot cardiovascular
disease - Algorithms for arterial pressure by automatic
vasoactive agents control (human)
POlHL-11310-12 0066 Mechanisms of cardiovascular
disease - Measurement of cardiac output by thermodilution
(children)
P01HL11310-12 0067 Mechanisms of cardiovascular
disease • Cardiac performance with measured
hemodynamic variables (human)
(contd)
•Excludes routine methodology OR covers only general projects which preclude
"Oriented significantly to above subject.
indexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
SUR
P01HL1131012 0068 Mechanisms of cardiovascular
disease ■ Phafmacoiogica! intervention and myocarcial
oxygen consuption (human, dogs)
POlHL-1 1310-12 0069 Mechanisms of cardiovascular
disease - Factors affecting mortality and morbidity after
heart surgery (human)
POlHL-11310-12 0071 Mechanisms of cardiovascular
disease ■ Electrophysiological studies of atrial flutter
(human)
POlHL-11310-12 0072 Mechanisms of cardiovascular
disease ■ Electrophysiological studies of atrial tachycardia
with block (human)
P01HL11310-12 0073 Mechanisms of cardiovascular
disease ■ Electrophysiological study of atrial fibrillation
(human)
POlHL-1131012 0074 Mechanisms of cardiovascular
disease ■ Electrophysiological studies of paraxysmal atrial
tachycardia (human)
POlHL-11310-12 0077 Mechanisms of cardiovascular
disease - Abnormalities of rhythm and conduction following
heart surgery (human)
POIHLI 1310-12 0082 Mechanisms of cardiovascular
disease - Myocardial function in adult congenital heart
disease (human)
** POlHL-1237310 0020 Cardiopulmonary physiology and
pathophysiology - Hospitalization and patient care
POlHL-13108-09 0009 Clinical heart transplantation - B
cell alloantigens in cardiac allograft compatibility (human)
POlHL-1310809 0011 Clinical heart transplantation -
Humoral and cellular kinetics of allograft rejection (human)
POlHL-13737-07 0029 Assisted circulation - Chronic left
ventricular failure (human)
POIHL 1519407 0017 Pathophysiology of
cardiopulmonary dysfunction - Coronary circulation and
effects of arteriographic lesions on flow (human)
ROlHL-1624606 Immunologic studies in
postpcricardiotomy syndrome (human)
ROIHL 16461-05 Late results of valve replacement -
Computer analysis (human)
P60HL- 17265-04 0007 Community blood resource center
support - Research-Massive transfusion and trauma
(human)
P60HL-1 7269-04 0026 National heart and blood vessel
research and demonstration center - Dynamics of ischemic
heart disease (human, dog)
" P60HL17269-04 0029 National heart and blood vessel
research and demonstration center - Clinical application of
circulatory assistance (human)
P50HL17651-04 0032 Ischemic heart disease specialized
center of research ■ Cardiovascular surgery core (human,
dogs)
P50HL 17667-04 0022 Study of ischemic heart disease -
Preventing myocardial injury in surgery using
cardiopulmonary bypass (human, rat)
ROlHL-17974-03 External pneumatic compression in deep
venous thrombosis (human)
M ROlHL-17993-04 Ventricular dynamics from surgically
inserted markers
ROIHLI 7993-04 0001 Ventricular dynamics from
surgically inserted markers • Effects of aortocoronary
bypass graft surgery on ventricular function (human)
ROlHL-1799304 0002 Ventricular dynamics from
surgically inserted markers - Left ventricle function In
human cardiac allograft
ROlHL-1799304 0003 Ventricular dynamics from
surgically inserted markers - Effects of pharmacologic
agents on left ventricular dynamics (human)
ROlHL-1799304 0004 Ventricular dynamics from
surgically inserted markers - Exercise training following
coronary artery bypass graft surgery (human)
ROlHL-1799304 0005 Ventricular dynamics from
surgically inserted markers - Cardiac dimensions and
dynamic after mitral, aortic valve surgery (human)
ROlHL-l 7993-04 0006 Ventricular dynamics from
surgically inserted markers - Atrial pacing in transplant
patients
ROlHL-1799304 0007 Ventricular dynamics from
surgically inserted markers - Digitalis after coronary artery
surgery (human)
R01HL1799304 0008 Ventricular dynamics from
surgically inserted markers • Exercise after coronary bypass
(human)
ROlHL-1799304 0010 Ventricular dynamics from
surgically inserted markers - Postoperative cardiovascular
visualization (human)
R01HL18923-02 Steroid-induced hyperlipidemia and
hypertension (human, rats)
ROlHL-1945103 0003 Functional characteristics of the
left heart ■ Left ventricular segmental contraction (human,
dogs)
ROlHL'20356-02 Development and evaluation of an
artificial heart (calves)
ROlHL-2080302 Intra-aortic balloon pumping (dogs,
lambs, cats)
ROlHL-20895'03 0001 CIneangiographic studies of
cardiovascular system ■ Videodensitometry and valvular
regurgitation (human, dogt)
ROlHL-20898-02 Ultrasonic evaluation In direct arterial
surgery (modili, cittli, humin)
R01HL21210-01 Acuti renil falluri following cardiac
iurgary (human)
502
ROlHL-21278-01 Abnormal cardiac wall motion viewed
ultrasonically (human, dogs, phantoms)
R01HL-2I548-01 Pathogenesis of pulmonary
thromboembolic disease (human, mammals)
ROlHL-21632-02 Development of a transcutaneous power
transfer system (cattle)
ROlHL-2215202 Ventricular dysfunction and cardiac
surgery (dogs)
ROlHL-22244-01 Cardiopulmonary bypass and the
vascular endothelium (dogs)
ROlHL-22321-01 Cardiac output from the
pneumocardiogram (dogs)
ROlHL-22661-01 Chronic total cardiopulhonary mechanical
substitution (sheep)
ROlHL-22894-01 Two dimensional ultrasound and cardiac
surgery (human, dogs)
N01HV-5300e-06 Evaluation of model VII left ventricular
assist device (human)
SURGERY, PREOPERATIVE
ROlHL-03181-21 0029 Hemodynamics as applied to
surgical problems Indocyanine green clearance for
estimation of hepatic blood flow (human)
POlHL-06835-17 0048 Cardiovascular disease -
Aldosterone producing adenoma prediction of curability
(human)
POlHL-06835-17 0049 Cardiovascular disease - Selective
hypoaldosteronism (human)
" ROlHL-0869615 0012 Orthotopic heart transplantation •
Transplantation immunology-Modulation of donor
antigenicity (dogs)
ROlHL-08696-15 0013 Orthotopic heart transplantation -
Transplantation immunology-Cardiac heterotransplantation
(rabbits, dogs)
" POlHL-13108-09 0002 Clinical heart transplantation ■
Preoperative immunologic studies of cardiac recipients
ROlHL-15676-06 The role of occult myocardial failure in
human shock (human, dogs)
** P60HL-17292-04 0029 Vermont Lung Center ■ Computer-
assisted preoperative evaluation (human)
ROlHL-20895-03 0001 CIneangiographic studies of
cardiovascular system - Videodensitometry and valvular
regurgitation (human, dogs)
ROlHL-20895-03 0003 CIneangiographic studies of
cardiovascular system - Densitometry in coronary stenosis
(human)
ROlHL-20895-03 0005
cardiovascular system
CIneangiographic studies of
Computerized axial tomography -
Cardiac wall motion and infarction (dogs)
ROlHL-20898-02 Ultrasonic evaluation in direct arterial
surgery (models, cattle, human)
R01HL21278-01 Abnormal cardiac wall motion viewed
ultrasonically (human, dogs, phantoms)
ROlHL-21533-02
(human)
ROlHL-22152-02
surgery (dogs)
ROlHL-22894-01
Platelet inhibitor drug In coronary surgery
Ventricular dysfunction and cardiac
Two dimensional ultrasound and cardiac
surgery (human, dogs)
NOlHR-32902-07 Pilot study to standardize the
measurement of closing volume (human)
SURGERY, THORACIC
SEE ALSO BLOOD AND RE SYSTEM, THYMECTOMY
SEE ALSO HEART SURGERY
SEE ALSO RESPIRATORY SYSTEM SURGERY
ROlHL-13172 10 Post-trauma lung mechanics and fluid
exchange (human, dogs, monkeys)
ROlHL-22894-01 Two dimensional ultrasound and cardiac
surgery (human, dogs)
SURGERY IN UTERO
SEE PREGNANCY, EMBRYO-FETUS SURGERY
SURGERY STUDY SECTION
" ROlHL-02363-20 Kinetics of water and electrolytes in
shock (dogs, rats)
** ROlHL-03180-21 Relation of lymphatics to
cardiopulmonary function (dogs)
ROlHL-03181-21 Hemodynamics as applied to surgical
problems
ROlHL-04651-19 Remote stimulation by radio-frequency
transmission (dogs, human)
R01HL0869615 Orthotopic heart transplantation
ROlHL-09315-15 Coronary insufficiency and myocardial
revascularization (human, dogs)
ROlHL-09609-11 Lung volume and breathing mechanics
during anesthesia (human)
ROlHL-11802-10 Cardiovascular surgical research (dogs.
sheep, swine, cats, monkeys)
R01HL11901-12 Effects of metabolic surgery on the
hyperlipidemias
ROlHL-1 19 19-08 Pulmonary circulation in surgical heart
disease (human, dogs)
ROlHL-1 1945-10 Synthesis of artificial lung and kidney
systems (sheep, mice, swine)
ROlHL-12322-10 Extrinsic factors Influencing myocardial
performance (dogs, swine)
ROlHL-12677-10 Surgical physiologic studies of Isolated
kidneys (dogs, rats)
R01HL-12777-09 Mechanisms in cardiac performance
(dogs, human)
ROlHL-12839-09 Flow, transport and membrane
phenomena In blood (human)
M
M
M
SUR
* ROlHL-1317210 Post-trauma lung mechanics and fluid
exchange (human, dogs, monkeys)
* ROlHL-13193-09 Pathophysiology of post-traumatic and
shock states (rodents, dogs)
* ROlHL-13257'09 Inhalation anesthesia on myocardial
metabolism (dogs, swine, human)
* ROIHL-13341-06 Lymph-An indication of splanchnic tissue
respiration (dogs, human, rats)
* R01HL13426-09 Left ventricular bypass for myocardial
infarction (cattle, human)
' ROlHL-1346608 Pulmonary platelets in shock, trauma
and embolization (dogs. pigs, rats)
* ROlHL-13754-08 Postoperative thromboembolism in
surgical patients (human)
' ROlHL-13803-07 Advanced cardiac valvular and vascular
prosthesis (dogs, baboons)
' ROlHL-13920-07 Expanding the role of surgery of atrial
dysrhythmias (dogs)
' ROlHL-13987-04 Transplantation of the lung (dogs)
' ROlHL-13988-07 Elimination of reoperative cardiac
pacemaker surgery (dogs)
' ROlHL-14126-17 Etfcct of function on grafts and implants
of collagen (dogs, monkeys)
* ROIHL 14378-07 Lipemias and reconstructive cardiac
surgery (human)
' ROlHL-14571-05 Myocardial preservation and coronary
reperfusion (baboons, dogs)
' ROlHL-14644-05 Optimization diastolic augmentation and
systolic sink (dogs)
* ROlHL-14799-07 Cardiac heterotransplantation--
Immunologic modification (mice, rat)
' R01HL15247-05 Extending the life of implanted
pacemakers (dogs, human)
' R01HL15448-06 Surgical and metabolic aspects of
venous grafts, (dogs, monkeys, rabbits)
' ROlHL-15520-06 Total blood replacement by fluorocarbons
and polyols (rats)
' R01HL15593-05 Prolonged extracorporeal cardiopulmonary
support (rats, sheep, rabbits)
■ ROlHL-15668-06 Extracorporeal respiratory gas exchange-
A new approach (dogs)
' ROlHL-15676-06 The role of occult myocardial failure in
human shock (human, dogs)
■ ROlHL-15799-04 Effect of anesthetics on myocardial
function (cats)
ROlHL-15813-05 Cardiac anoxia-Protective effect of
carbohydrate (dogs)
R01HL161 19-05 Spleen and marrow allografts In
hereditary anemia (mice)
ROlHL-16154-05 Membrane lung perfusion for acute
respiratory failure (sheep, baboons)
ROIHL-16246-06 Immunologic studies In
postpericardiotomy syndrome (human)
ROlHL-1629205 Surgery and non-obstructive coronary
insufficiency
ROlHL-16329-04 Cardiac surgical effect on heart function
in infants (human)
ROlHL-16582-05 Artificial lungs (dogs)
ROlHL-16711-05 RBC and endothelial membrane material
characteristics (human)
ROIHL 16921 OS Synthetic hydrogels as blood tolerable
materials
ROlHL-16935-05 Tissue organization and turnover in the
semilunar valve (dogs, rats)
ROlHL-16938-05 Effect of physical forces on blood (dogs,
human)
ROlHL-17091-05 Anesthetics and microvascular response
to hemorrhage (rats)
ROlHL-17332-04 Use of the gut for therapy of coronary
artery disease (mammals)
ROIHL 17358 04 Ventilatory adjustments for optimal
oxygenation (dogs, rats)
ROlHL-17369-04 Arterial bypass surgery-Structure and
metabolism (monkeys)
ROlHL-17437-03 'Perfusion lung' -Role of traumatized
leukocytes (dogs, human)
ROIHL- 174 79-04 Blood storage-The production of
cardiotoxic material (dogs, human, swine)
ROlHL-17623-05 Initial events in thrombus formation on
surfaces (human, rats)
ROlHL-17759-03 Studies of myocardial reactive hyperemia
(dogs, human)
ROlHL-17821-03
devices
ROlHL-17844-04
Iron chelates (human, mammals)
Cavitation phenomena near prosthetic
Artificial blood substitutes -02-bindlng
ROlHL-17859-04
dynamics
ROlHL-17944-03
ROlHL-l 7969-04
valves (dogs)
ROlHL-17974-03 External pneumatic compression in deep
venous thrombosis (human)
ROlHL-17993-04 Ventricular dynamics from surgically
Computational methods in cardiac fluid
Studies In lung preservation (dogs)
Function and structure of semilunar
inserted markers
R01HL-18002-03
function (rats)
ROIHL- 18040-04
(calves)
R01HL-180e4-03
(calves)
*E(clud« routine methodology OR coven only general projects which pnclude Indexing at the specific level.
"Orlenttd ilgnlflcintly to ebove subject.
M (Jrint his lubpnijects describing specific research ispecti.
See Appendix for Investigator's name end grant number.
Circulatory shock, trauma and RE-systam
Waveform dependency In defibrillation
Artificial heart and rilatad problems
(contd)
SUR
Human anatomy tor cardiac prostlieses
Prosthesis lor aortocoronary bypass
Heart preservation and transplantation
Pulseless flow and circulatory assistance
ROIHl 1809604 Vasoactive agents in splanclinic viscera
(primates, dogs)
ROIHI 18143 03 Surgery and pulmonary tissue alterations
(dogs, rats, human)
ROIHL 1828804 Intraoperative protection ol the
myocardium (dogs, rats)
ROIHL 18321 03 Fluid shear or magnetic alignment of
blood components (human)
ROIHL 1846001 Effects of prolonged hypoperfusion on the
myocardium (rabbits)
ROIHL 18S1903 Albumin, endothelium and
hemocompatibility (human, dog. cattle, rabbit)
ROIHL 1863903
(human)
ROIHL 18644 03
(dogs, baboons)
ROIHL'18731 02 RES stimulating materials In
experimental shock (dogs)
R01Hl'18738'02 Prevention of postoperative venous
thrombi (human, cattle)
ROIHL 1876203 Posttraumatic pulmonary insufficiency
(dogs)
ROIHL' 18764-03 Biosorbable thromboresistant surfaces
(dogs, rats, swine, human)
ROIHL'1881503 Surgical vascular disorders (human.
dogs)
' ROIHL 1893602
studies (rat)
■ ROIHL 1894803
(dogs, calves)
' ROIHL'18995'04 Cardiovascular determinants of
catecholamine release (dogs)
' ROIHL 18997-02 Ischemic therapy in experimental
hypersplenism (rats, dogs)
' R01HL19030-03 Tissue protection during circulatory
interruption (dogs)
* ROIHL- 19038-02 Plethysmographic evaluation of carotid
blood flow (human, rabbits, dogs)
' ROlHL-19055-03 Platelet function during extracorporeal
perfusion (human, mammals)
' ROlHL-19173-03 Analysis of blood trauma from
microporous oxygenators (human, dogs, rabbits)
' ROlHL-19182-03 Surgical aspects of myocardial
hypertrophy (dogs)
' ROlHL-19203-03 Surgical approach to congenital heart
diseases (dogs, primates)
* ROlHL-19350-02 Prevention of thrombosis by applied
electric fields (sheep)
* R01HL19414-03 Protection of myocardium during cardiac
surgery (dogs, cats, human)
' ROIHL- 194 19-03 Cellular interactions with foreign
materials (mammals)
* R01HL19673-03 Surgical aspects of shock and hypoxia
(dogs, monkeys, rats)
* ROlHL-19818-02 Endocarditis on prosthetic heart valves
(rabbits, human)
* ROlHL-19993-02 Optical detection of platelet aggregates
(human, baboons)
* ROlHL-20037-02 Left ventricular-aortic bypass and
composite prosthesis (sheep, swine, cattle)
* ROlHL-20073-02 Blood compatible materials by fluid
perfusion (human, dogs)
Thromboresistant material
Surgically induced myocardial edema
Circulatory control of splenic function
ROlHl-20079-02
ROlHL-20080-02
(dogs)
ROlHL-20086-02
(rats)
ROlHL-20143-02 Hypothermic circulatory arrest-Cerebral
vascular change (dogs)
ROlHL-20 163-02 Competitive coronary flow in native and
graft vessels (dog)
ROlHL-20170-02 Pulmonary infection in splenectomized
animals (mice)
ROlHL-20219-02
(rats)
R01HL-20226-02
physiology (dogs)
ROlHL-20251-02 A novel approach to nonthrombogenic
polymer surfaces (sheep, cattle)
ROlHL-20313-02 Surface-induced thrombosis-Modification
of albumin variants (human, goat)
R01HL-203S602 Development and evaluation of an
artificial heart (calves)
ROlHL-20554-02 Memoiy-alloy-filfers for venous emboli
(dogs)
ROlHL-20629-02
(dogs)
ROlHL-20632-02
ROlHL-20720-02
Cryopreservation of the isolated heart
Cardiac bypass and coronary collateral
Catheter ventricular defibrillation studies
An optimal fetal heart monitor (human)
Myocardial protection during
cardiopulmonary bypass (dogs)
Anesthetic-induced myocardial depression
Intra-aortic balloon pumping (dogs.
ROlHL-20754-02
(rabbits)
ROlHL-20803-02
lambs, cats)
ROlHL-20829-02 Fluid mechanics of heart valve
prostheses (dogs, human)
ROlHL-20835-02 Signal analysis of turbulence study In
blood
ROlHL-20895-03 CIneanglogrsphic studies of
cardiovascular system
ROlHL-20979-02 A novel pulsed Doppler flowmeter (dogs)
S03
ROIHI 21001 01 Protein and thrombus deposition on
vascular traits
ROIHI 21071 0? Mechanisms of hypertension in
coarctation of the aorta (dog)
ROIHL 210/6 02 Lung fluid, protein exchange after
hemorrhagic shock (sheep)
ROIHL 21188 02
desquamation
R01HL2119402
biomaterials
ROIHL 2121001
surgery (human)
ROIHL 21270-01 Correlation ol arterial hemodynamics and
morphology (human)
R23HL 21271 02 Extracorporeal circulation and protein
denaturation (human)
ROIHL 21293-02
surgery (human)
Pulsatory water flux and endothelial cell
Development ol antithrombogenic plastic
Acute renal lailure lollowing cardiac
Randomized study ol coronary bypass
Accessory pathways and supraventricular
Platelet inhibitor drug in coronary surgery
Natural history of the postphlebitic
R23HL2134702
tachycardia
R01HL21533O2
(human)
ROIHL 2157201
syndrome
ROlHL-21632 02 Development of a transcutaneous power
transfer system (cattle)
ROlHL-21674 01 Development of automatic implanted
defibrillator (dogs, cattle)
R01HL21786-01 Long-term effects of myocardial
protection (dogs, rats)
R01HL21796-01 Applied pulsatile hemodynamics in
vascular surgery (dogs)
R23HL21805-01 Tissue cell interactions with vascular
prostheses (human, rats, mice)
ROlHL-2 1859-01 Unsteady flow in arterial bifurcations
(human)
R01HL21969-01 Prevention of myocardial hypoxia during
by-pass (rats. mice, squirrels)
ROIHL 22005-01 Intermittent retroperfusion of ischemic
myocardium (dogs)
ROlHL-22069-02 Experimental renal arterial hypertension
(dogs)
ROlHL-22098-01 Is postoperative infarction due to
reperfusion injury? (human, dogs)
ROlHL-221 10-02
grafting (dogs)
Healing complications in vascular
Ventricular dysfunction and cardiac
Characterization of bio-materials by
Transport of arterial blood gases through
Active prosthetic myocardium-Effects on
ROlHL-221 52-02
surgery (dogs)
ROlHL-22233-01
elastic property
ROlHL-22244-01 Cardiopulmonary bypass and the
vascular endothelium (dogs)
ROlHL-22274-01 Quantitating in series effects in cardiac
arrhythmias (dogs)
ROlHL-223 15-01 Intraoperative cardiac oxygen supply-
demand (dogs, rabbits, rats)
ROlHL-22321-01 Cardiac output from the
pneumocardiogram (dogs)
ROlHL-22326-01 Noninvasive measurement of cardiac
output (dogs)
ROlHL-22327-01
skin (swine)
ROlHL-22329-01
LV function (dogs)
R01HL-22338-01 Platelet adhesion and aggregation in a
flow chamber (human)
R23HL-22346-01 Hematological injury and pulmonary
dysfunction (human, mammals)
ROlHL-22413-01 Enhanced detection of bubbles in
Doppler flow signals (human)
ROlHL-224 17-01 Microprocessors in medical applications
(dogs)
ROlHL-22445-01 Platelet inhibitors-Effect on coronary
bypass grafts (dogs)
R23HL-22448-01 Modulation of heart graft antigenicity by
perfusion (rats)
ROlHL-22455-01 Platelet concentration in the marginal
layer (dogs, human)
ROlHL-22517-01 Engineering development of an ultrasonic
ventilometer (human)
ROlHL-22573-01 Treatment of post surgical
vasoconstriction (dogs, monkeys, human, rats)
ROlHL-22585-01 Plasma proteins adsorbed to artificial
organs (human, rabbits)
ROlHL-22604-01 Non-invasive system for arteriosclerosis
studies (human)
ROlHL'22627-01 An inhibitor of platelet adhesion to
artificial organs (human)
ROlHL-22636-01 Newborn lung function during
mechanical ventilation (human)
ROlHL-22661-01 Chronic total cardiopulhonary mechanical
substitution (sheep)
' R01HL-22699-01 Defibrillation electrode studies (dogs,
swine)
' R01HL-22741-01 Arteriovenous connections in extremity
revascularization (dogs)
' ROlHL-22759-01 Regional myocardial blood flow during
hypothermia (dogs)
' ROlHL-22783-01 Hemodynamic induction of intimal
fibromuscular lesion
' ROlHL-22784-01 Ductus arteriosus closure~An arterial
lesion model (rabbits)
SVN
" R23HL22/8/0I Cardiac volume by biplane
echocardiography (human)
** ROIHL 22801 01 Analyiii ol coronary artery behavior
(dogs)
•* ROIHL 22815 01 Regional myocardial function alter
revascularization (dogs)
•• ROIHL 2284401 Phrenic nerve pacing Noninvasive
diaphragm analysis (human, dogs)
•• ROIHL 2285201 Diagnostic techniques in venous
thromboembolism (human)
" ROIHL 22854 01 Non invasive blood pressure
measurement (rats)
•* ROIHL 22888 01 Prosthetic valve endocarditis-Etiology
and therapy (dogs)
*• ROIHL 22893-01 Evaluating arterial disease by velocity
wave analysis (dogs, human)
** ROIHL 22894 01 Two dimensional ultrasound and cardiac
surgery (human, dogs)
** R01HL2311401 Control ol platelet aggregation in shock
(dogs, rabbits)
** ROlHL-2361801 Substrate metabolism in isolated
myocytes in shock (dogs. rats, guinea pigs)
** ROIHL 2389901 Flow and flexing at blood/biomaterial
interfaces
SURGICAL ADHESIVES
POIHL 13738 08 0005 Cardiac assist devices and
artificial hearts Development of new materials for
artificial heart and assist devices (sheep, dog)
** ROIHL 1793003 Platelet membrane function Assessment
and application (animals)
N01HV82919-00 Development of percutaneous energy
transmission systems
SURGICAL SUTURES
ROlHL-1 1945-10 Synthesis of artificial lung and ktdney
systems (sheep, mice, swine)
SURGICAL WOUND INFECTION
SEE INJURIES, SURGICAL WOUND INFECTION
SURGICAL WOUNDS
SEE INJURIES. SURGICAL WOUNDS
SURVEYS, HEALTH
SEE POPULATION SURVEYS, HEALTH SURVEYS
SURVEYS, POPULATION
SEE POPULATION SURVEYS
SUSPENSIONS (DOSAGE FORM)
SEE DOSAGE FORMS
SUSPENSIONS (PHYSICAL CHEMISTRY)
SEE PHYSICAL PROPERTIES, SUSPENSIONS
SUSTAINED RELEASE PREPARATIONS
SEE DOSAGE FORMS
SUTURES
SEE SURGICAL SUTURES
SV40 VIRUS
SEE VIRUSES, PAPOVAVIRUSES, SV40 VIRUS
SWALLOWING
SEE GASTROINTESTINAL FUNCTION, DEGLUTITION
SWEAT
SEE SKIN SECRETIONS, SWEAT
SWIMMING
SEE WATER ENVIRONMENT, DIVING AND SWIMMING
SWINE, MINIATURE
SEE MAMMALS, ARTIODACTYU, SWINE, MINIATURE SWINE*
SYMPATHECTOMY
SEE NEUROSURGERY, SYMPATHECTOMY
SYMPATHETIC GANGLIA
SEE NERVOUS SYSTEM AUTONOMIC, SYMPATHETIC GANGLIA
SYMPATHETIC NERVOUS SYSTEM
SEE NERVOUS SYSTEM AUTONOMIC, SYMPATHETIC NERVOUS
SYSTEM
SYMPATHOLYTIC AGENTS
SEE NEUROPHARMACOLOGICAL AGENTS, SYMPATHOLYTIC
SYMPATHOMIMETIC AGENTS
SEE NEUROPHARMACOLOGICAL AGENTS, SYMPATHOMIMETIC
SYMPOSIA
SEE INFORMATION DISSEMINATION, MEETINGS CONFERENCES
SYMPOSIA
SYNAPSES
SEE NERVOUS SYSTEM, NERVE ENDINGS, SYNAPSES
SYNAPTIC RECEPTORS
SEE NEUROTRANSMinERS RECEPTORS
SYNAPTIC VESICLES
SEE NERVOUS SYSTEM, NERVE ENDINGS, SYNAPTIC
VESICLES
SYNAPTOSOMES
SEE NERVOUS SYSTEM, NERVE ENDINGS, SYNAPTOSOMES
(contd)
'Encludet routine melhodotogy OR covert only general projects which preclude Indexing at the specific level,
"Oriantad ilgnlflcantly to above subject.
M Grant has lubprejectt describing specific research aspects.
See Appendix for Investigator's name and grant number.
SYN
504
TEM
SYNCHRONOUS CELL DIVISION
SEE CELL DIVISION. SYNCHRONOUS CELL DIVISION
SYNCOPE
SEE NEUROLOGIC MANIFESTATIONS. SYNCOPE
SYNERGISM
SEE DRUGS AND PHYSICAL AND/OR CHEMICAL AGENTS
INTERACTION
SEE DRUGS INTERACTION
SEE PHYSICAL AND/OR CHEMICAL AGENTS INTERACTION
(BIOLOGICAL AND ECOLOGICAL)
SYNTHESIS (ORGANIC)
SEE CHEMICAL SYNTHESIS AND PRODUCTION
SYNTHESIS OF DRUGS
SEE DRUGS SYNTHESIS AND PRODUCTION
SYNTHETASES
SEE LIGASES
SYNTHETIC LETHALS
SEE GENETICS. GENES. GENE EXPRESSION, LETHALS
SYSTEAAATIC BIOLOGY
SEE BIOLOGY. SYSTEMATIC
SYSTEMS ANALYSIS
SEE INFORMATION AND COMMUNICATION, SYSTEMS ANALYSIS
T-DIAPHORASE
SEE OXIDOREDUCTASES. NAD(P)H DEHYDROGENASE
(QUINONE)
TABLETS
SEE DOSAGE FORMS
TACHYCARDIA
SEE HEART DISORDERS. ARRHYTHMIA, TACHYCARDIA
TACHYPHYLAXIS
SEE DRUGS TACHYPHYLAXIS
TADPOLES
SEE AGE (ANIMAL). IMMATURE, LARVA
TAMARINS
SEE MAMMALS, PRIMATES. MONKEYS AND APES
(ANTHROPOIDS, NON-HUMAN), NEW WORLD MONKEYS
(PLATYRHINES)*
TAMPONADE, CARDIAC
SEE HEART DISORDERS. CARDIAC TAMPONADE
TANGIER DISEASE
SEE METABOLIC DISORDERS INBORN,
HYPOLIPOPROTEINEMIAS FAMILIAL, TANGIER DISEASE
TANTALUM
SEE METALS, HEAVY METALS, TANTALUM
TARICHATOXIN
SEE TOXICOLOGY, ANIMAL POISONS, TETRODOTOXIN
TASTE THRESHOLD
SEE SENSORY-PERCEPTUAL PROCESSES, TASTE THRESHOLD
TAURINE
SEE AMINOSULFONIC ACIDS, TAURINE
TAXONOMY
SEE BIOLOGY, SYSTEMATIC
TCDD
SEE HALOBENZENES, HALOGENATED BIPHENYLS-TRIPHENYLS
AND ANALOGS
TCDF
SEE HALOBENZENES, HALOGENATED BIPHENYLS-TRIPHENYLS
AND ANALOGS
TEACHING
SEE EDUCATION, TEACHING
TEACHING MACHINES
SEE EDUCATION, PROGRAMMED INSTRUCTION, TEACHING
MACHINES
TECHNETIUM RADIOISOTOPES (99)
SEE RADIOISOTOPES, TECHNETIUM
TEFLON
SEE RUSTICS, FLUOROCARBON POLYMERS
TELA CHOROIDEA
SEE BRAIN, CENTRAL SPACES, CHOROID PLEXUS
TELE(RADIOFREQUENCY)ELECTRONIC
STIMULATORS
SEE ELECTRONIC STIMUUTORS, RADIOFREQUENCY
CONTROLLED
TELEMEDICINE (GENERAL)
SEE BIOMEDICAL SYSTEMS AUTOMATED, TELEMEDICINE
(GENERAL)
TELEMETERING
SEE BIOMEDICAL SYSTEMS AUTOMATED, TELEMETERING AND
REMOTE SENSING
TELENCEPHALON
SEE BRAIN, CEREBRUM
TEMPERAMENT
SEE PSYCHOLOGY, PERSONALITY
TEMPERATURE (SEE ALSO THERM...)
SEE ALSO SENSORY-PERCEPTUAL PROCESSES,
THERMORECEPTION
POlHL-07896-15 0029 Environmental biomedical research
program - Oxygen-helium diving resulting in high pressure
nervous syndrome (human, animals)
POlHL-07896-15 005C Environmental biomedical research
program - Fundamental decompression concepts using the
rat animal model
ROlHL-08359-14 Morphopharmacology of vascular
adrenergic transmission (rabbits, rats)
ROlHL-12174-11 Ventilation/perfusion distribution in the
lung (human, mammals)
** R01HL-12879-09 0007 Pulmonary transport and
metabolism in vivo - Effects of temperature changes on
pulmonary transport
ROlHL-12879-09 0011 Pulmonary transport and
metabolism In vivo - Membrane characteristics of lung
cells (human, animals)
POlHL-14388-07 0185 Regulation of the circulation in
pathological states - Reflex control of venous tone (human,
rabbits, dogs)
POlHL-144 14-07 0010 Environmental influences on
cardiorespiratory and cellular functions - Pressure effects
on cardiac electrical phenomena (animals)
** POlHL-144 14-07 0014 Environmental influences on
cardiorespiratory and cellular functions - Temperature and
acid-base status in tissues, cells, and subcellular system
POlHL-15194-07 0009 Pathophysiology of
cardiopulmonary dysfunction - Kinetics of gas exchange-
Diffusion and erythrocytes reaction rates (human, dogs)
POlHL-15835-06 0011 Study of muscles related to heart
disease - Energetics and mechanism of muscle contraction
(frogs, rabbits)
POlHL-16833-04 0003 Hemoglobin and red cell system in
hemoglobinopathies - Oxygen binding curves and equilibria
(human)
R01HL-17576-04 Role of sphingomyelin in biomembranes
and bilayers (rats, other mammals)
ROlHL-17944-03 Studies in lung preservation (dogs)
R01HL18082-03 Erythrocyte phosphates and vertebrate
gas transport (amphibians, reptiles)
POlHL-19737-02 0007 Cellular and molecular aspects of
respiratory physiology - Average oxygen tension of tissue
using radioisotopes (dogs)
ROlHL-20262-02 Cardiac glycosides and the mechanism
of the sodium-potassium pump
ROlHL-20635-03 Factors in lung development (rat and
chick embryo)
POlHL-20994-02 0009 Dynamics of neutrophil elastase in
the lung - Biosynthesis and degradation of elastin in
emphysema (human, hamsters)
POlHL-21016-02 0005 Sickle cell anemia and other
hemoglobinopathies - Ligand kinetics in normal and Hb S
containing erythrocytes (human)
POlHL-21016-02 0006 Sickle cell anemia and other
hemoglobinopathies - Analysis of the oxygen dissociation
curve of Hb S-containing red cells
ROlHL-22008-01 Left ventrivular calcium content and
contractility (rats)
ROlHL-23900-01 Mechanical measurement of cell
membrane viscosity (human)
TEMPERATURE, COLD
SEE ALSO BLOOD COAGULATION, CRYOFIBRINOGEN
SEE ALSO ENVIRONMENT, CLIMATE, COLD
SEE ALSO ENVIRONMENT, STRESS, COLD INDUCED
SEE ALSO GLOBULINS, CRYOGLOBULINS
SEE ALSO TEMPERATURE (BODY), HYPOTHERMIA
R01HL-22928-01 Systematic study of bronchial circulation
(sheep)
TEMPERATURE, CRYOPROTECTIVE AGENTS
** POlHL-06312-17 0033 Surgical cardiology - Studies in
cryopreservations (rats)
** ROlHL-202 19-02 Cryopreservation of the isolated heart
(rats)
TEMPERATURE, CRYOSCIENCES
SEE ALSO TEMPERATURE (BODY), HYPOTHERMIA INDUCED,
CRYOSURGERY
SEE ALSO TEMPERATURE (BODY), HYPOTHERMIA INDUCED,
CRYOTHERAPY
R01HL-14508-10 Structure and function of respiratory
hemoproteins
ROlHL-19203-03 Surgical approach to congenital heart
diseases (dogs, primates)
TEMPERATURE, CRYOSCIENCES, LOW
TEMPERATURE PRESERVATION AND STORAGE
** POlHL-063 12-17 0033 Surgical cardiology - Studies in
cryopreservations (rats)
** POlHL-090 11-15 0022 A research and resource program
in blood Cryopreservation of blood components (human)
R01HL-1412G-17 Effect of function on grafts and implants
of collagen (dogs, monkeys)
R01HL15647-06 Hematopoietic studies of cyclic
hematopoiesis (dogs)
P60HL- 17265-04 0006 Community blood resource center
support ■ Research -Evaluation of platelet transfusions
(human, dog)
P60HL-17265-04 0007 Community blood resource center
support - Research -Massive transfusion and trauma
(human)
Studies in lung preservation (dogs)
Heart preservation and transplantation
ROlHL-17944-03
ROlHL-18936-02
studies (rat)
ROlHL-20219-02
(rats)
ROlHL-20695-02
ROlHL-20716-02
platelets (rats)
ROlHL-207 18-02
platelets
NOlHR-62930-03
Cryopreservation of the isolated heart
Stored plateletes (human)
Freezing and electromagnetic thawing of
Microstructural integrity of stored human
Lung cell resource facility
TEMPERATURE, FREEZE-ETCHING*
** POlHL-161 17-05 0001 Ion movements and membranes in
cardiovascular control - Developmental studies of
contractile cell junctions (rats, rabbits, elasmobranch)
P01HL-ie607-05 0007 Calcium ion and control of
cardiovascular function - Ultrastructure and conformation
in sarcoplasmic reticulum (rabbits)
P50HL-19171-02 0009 Pulmonary SCOR-Lung injury by
childhood infections - Host-parasite interaction-Scanning
electron microscopy, freeze-fracture methods
** POlHL-20592-02 0014 Cell biology of cardiac and
skeletal muscle - Core laboratory
TEMPERATURE, FREEZING
ROlHL-20716-02 Freezing and electromagnetic thawing of
platelets (rats)
TEMPERATURE, HEAT
SEE ALSO ENVIRONMENT, STRESS, HEAT INDUCED
SEE ALSO INJURIES, TEMPERATURE DEPENDENT, HEAT
INDUCED
SEE ALSO SENSORY-PERCEPTUAL PROCESSES,
THERMORECEPTION
POlHL-12157-11 0057 Functions and mechanisms of cell
membrane ion transport - Electrophysiological
investigations of synthetic strands of heart muscles (rats)
ROlHL-19352-03
neonates
ROlHL-21126-02
children
Respiratory heat and water loss in
Exercise-induced bronchospasm in
TEMPERATURE, HEAT, CALORIC STIMULATION
** POlHL-14388-07 0184 Regulation of the circulation in
pathological states - Vestibular reflexes in control of
circulation (human)
** ROlHL-20077-02 External cardiac stimulation with
microwave radiation (dogs)
TEMPERATURE, HEAT, CALORIMETRY*
ROlHL-20365-03 Molecular mechanisms of anion transport
TEMPERATURE, HEAT, MICROWAVE HEATING
** ROlHL-20077-02 External cardiac stimulation with
microwave radiation (dogs)
** ROlHL-20716-02 Freezing and electromagnetic thawing of
platelets (rats)
TEMPERATURE, HEAT STABILITY-LABILITY
** POlHL-07896-15 0036 Environmental biomedical research
program - Respiratory heat loss in deep diving (infants,
dogs)
ROlHL-20241-02 Shear and area moduli for abnormal red
cell membranes (human)
** ROlHL-20554-02 Memory-alloy-filters for venous emboli
(dogs)
TEMPERATURE (BODY)
SEE ALSO TEMPERATURE MEASUREMENT, THERMOGRAPHY*
ROlHL-04651-19 Remote stimulation by radio-frequency
transmission (dogs, human)
** POlHL-06285-18 0195 Cardiovascular-respiratory
physiology and biochemistry - Thyroid thermogenesis and
sodium transport (rats)
** P01HL07896-15 0036 Environmental biomedical research
program - Respiratory heat loss in deep diving (infants,
dogs)
Micropinocytosis in isolated capillary
ROlHL-16666-05
endothelium
R01HL16730-03
frogs, rabbits)
ROlHL-17958-04
Physiology of mucociliary transport (rats.
Circulatory effects of operant
cardiovascular control (baboons)
ROlHL-19352-03
neonates
ROlHL-20399-03
mellitus (dog)
ROlHL-20554-02
(dogs)
ROlHL-20634-01
Respiratory heat and water loss in
Vascular control in experimental diabetes
Memory-alloy-filters for venous emboli
Blood volume and venous return in
thermal strain (human)
ROlHL-20766-02
(baboons)
ROlHL-20861-01
(dogs)
ROlHL-21329-02
Control of circulation in heat stress
Cardio-resplratory-renal stress reactions
Beta-receptor regulation and cardiac
sites of drug action (cat, guinea pig, rat)
'Excludes routine methodoloey OR covers only general projects which preclude indexing at the specific level.
"Onented significantly to above subject.
•' ■ : ' hHs S"' .;.Cjects describing specific ress.
iw Appendix (of investigator's name and graril ■"
TEM
ROIHI 2USI 01 Control ol circulation durln( litat stress
and Itvtr (baboon)
ROIHI 22418 01 Neural control ol cardiorespiratory
function (cats)
TEMPERATURE (BODY), FEVER
SEE ALSO NEUROPHARMACOLOGICAL AGENTS, ANALGESICS.
ANIIPYRLIICS
POIHL 08899 14 0041 Tolerance to respiratory gases in
health and disease Blood gas transport and brain
circulatory control (human)
•* ROIHL 17352 03 Physiological regulation during chronic
hyperthermia (sheep)
** ROlHL-2145101 Control ol circulation during heat stress
and tever (baboon)
TEMPERATURE (BODY), HYPERTHERMIA
INDUCED
SEE ALSO INJURIES, TEMPERATURE DEPENDENT, HEAT
INDUCED
ROIHL 20077 02 External cardiac stimulation with
microwave radiation (dogs)
TEMPERATURE (BODY), HYPOTHERMIA
SEE ALSO ENVIRONMENT, ADAPTATION, HIBERNATION
P01HL0628518 0164 Cardiovascular respiratory
physiology and biochemistry CPK MB isoenzyme
concentration to quantify infarct size (human, animals)
P01HL08682 15 0006 Regulation of the cardiovascular
system Cardiovascular studies of mammalian hibernators
(sciuromorpha)
P01HL08899 14 0026 Tolerance to respiratory gases in
health and disease Effects of oxygen on central nervous
system functions (rats, rabbits)
POlHL-10435-13 0006 A multidisciplinary study of
congenital heart disease Ventricular blood pumps and
valves (human, cattle)
" R01HL147 13-06 Hypothermia and the heart (bats, guinea
pigs)
P50HL17651-04 0032 Ischemic heart disease specialized
center of research • Cardiovascular surgery core (human,
dogs)
P01HL1864603 0010 Studies basic to heart
transplantation - Development and study of a heart
preservation chamber (dogs, sheep)
ROlHL-2037102 Intravascular redistribution of blood
volume (dogs)
** ROlHL-21786-01 Long-term effects of myocardial
protection (dogs, rats)
ROlHL-22873-01 Adrenoceptor interconversion and
hormone homeostasis
ROlHL-22928-01 Systematic study of bronchial circulation
(sheep)
ROlHL-23736-04 Sickle cell anemia and hemoglobin
synthesis (monkeys)
TEMPERATURE (BODY), HYPOTHERMIA INDUCED
SEE ALSO SENSORY DEPRESSION, ANESTHESIA,
REFRIGERATION
** POlHL-06312-17 0044 Surgical cardiology - The limits of
topical cardiac hypothermia v»ith ice chips (rats)
POlHL-12738-10 0094 Physiologic pharmacology and its
clinical applications - Ventricular function and structure
(human, dogs)
ROlHL-15676-06 The role of occult myocardial failure in
human shock (human, dogs)
** ROlHL-16292-05 0018 Surgery and non-obstructive
coronary insufficiency ■ Unavoidable subendocardial
perfusion caused by venting and hypothermia (dogs)
P50HL-17665-04 0021 Study of ischemic heart disease -
Identification, prevention -Myocardial ischemia in
cardiopulmonary bypass (dog)
** P50HL-17667-04 0022 Study of ischemic heart disease -
Preventing myocardial injury in surgery using
cardiopulmonary bypass (human, rat)
ROlHL-19182-03 Surgical aspects of myocardial
hypertrophy (dogs)
** ROlHL-19203-03 Surgical approach to congenital heart
diseases (dogs, primates)
ROlHL-19414-03 Protection of myocardium during cardiac
surgery (dogs, cats, human)
ROlHL-20080-02 Surgically induced myocardial edema
(dogs)
** ROlHL-20143-02 Hypothermic circulatory arrest-Cerebral
vascular change (dogs)
ROlHL-20720-02 Myocardial protection during
cardiopulmonary bypass (dogs)
** ROlHL-22759-01 Regional myocardial blood flow during
hypothermia (dogs)
ROlHL-22894-01 Two dimensional ultrasound and cardiac
surgery (human, dogs)
TEMPERATURE (BODY), HYPOTHERMIA
INDUCED, CRYOSURGERY
" ROlHL-16292-05 0002 Surgery and non-obstructive
coronary insufficiency - Effects of hypothermia during
cardiopulmonary bypass (dogs)
P50HL-1 7670-04 0008 Study of ischemic heart disease -
Surgical treatment of cardiac rhythm disorders (human,
dogs)
SOS
TEMPERATURE (BODY), HYPOTHERMIA
INDUCED, CRYOTHERAPY
P60HI 15168 0/ 000b Comprehensive sickle cell disease
center Ophthalmology (human, rabbits, monkeys)
P50HL 1/665 04 0020 Study of ischemic heart disease
Ischemic iniury to myocardium during measured states of
ischemia (human)
TEMPERATURE (BODY), POIKILOTHERMS
POIHL 14414 0/ 0014 Environmental influences on
cardiorespiratory and cellular functions Temperature and
acid base status in tissues, cells, and subcellular system
TEMPERATURE (BODY) REGULATION
** R01HL02228 24 Respiration, circulation, and heal
regulation in exercise (bird, mammals)
P01HL07896-15 0033 Environmental biomedical research
program Breathing mechanism in birds
** P01HL0789615 0053 Environmental biomedical research
program Thermoregulation in asthmatics
POIHL 08682 15 0006 Regulation of the cardiovascular
system Cardiovascular studies of mammalian hibernators
(sciuromorpha)
POIHL 08899 14 0007 Tolerance to respiratory gases in
health and disease Effects of high oxygen pressures on
visual function (human, animals)
POlHL-08899 14 0018 Tolerance to respiratory gases in
health and disease Effects of respiratory gases at
extreme pressures (human)
P01HL08899 14 0026 Tolerance to respiratory gases in
health and disease Effects of oxygen on central nervous
system functions (rats, rabbits)
POIHL 16910-05 0008 Regulation of the peripheral
circulation Circulation to bone (dogs, baboons)
** ROlHL-17732 03 Peripheral venomotor control in thermal
stress (human)
ROlHL-20634-01 Blood volume and venous return in
thermal strain (human)
ROlHL-20663-02 Regulation of skin blood flovn in man
** ROlHL-21323-02 Raynaud's disease and temperature self-
regulation (human)
ROlHL-229 10-01 Control of breathing pattern in health
and disease (human, animals)
TEMPERATURE JUMP METHOD
SEE CHEMISTRY, ANALYTICAL METHODS, TEMPERATURE
JUMP*
TEMPERATURE MEASUREMENT,
THERMOGRAPHY*
** P50HL-17651-04 0038 Ischemic heart disease specialized
center of research - Cardiothermography (human, dog)
** ROlHL-19848-02 Contractile activation by rapid
temperature jumps (frogs)
TEMPERATURE SENSE
SEE SENSORY-PERCEPTUAL PROCESSES, THERMORECEPTION
TEMPERATURE SENSITIVE MUTANTS
SEE GENETICS, MUTATION, MUTANTS, TEMPERATURE
SENSITIVE MUTANTS*
TEMPORAL ARTERITIS
SEE CEREBROVASCULAR DISORDERS, TEMPORAL ARTERITIS
TENSILE STRENGTH
SEE PHYSICAL PROPERTIES. TENSILE STRENGTH
TEORELL MEMBRANE OSCILLATOR
SEE BIOLOGICAL TRANSPORT, MEMBRANE PERMEABILITY
AND TRANSPORT
TERATOGENIC AGENTS
SEE CONGENITAL ABNORMALITIES, TERATOGENIC AGENTS
TERBUTALINE
SEE PHENYLALKYLAMINES, TERBUTALINE
TERPENES, CAROTENOIDS
SEE ALSO PIGMENTS. BACTERIAL, BACTERIORHODOPSIN-
RETINAL
SEE ALSO VITAMIN A
ROlHL-20352-02 Defenses of lung cells against oxygen
toxicity (human, animals)
TERPENES, FARNESYL COMPOUNDS
ROlHL-15476-05 Mechanism and control of sterol
biosynthesis (rats)
ROlHL-16101-05 Protein-lipid interaction (bacteria,
models)
TERPENES, SQUALENE
ROlHL-02477-23 Biosynthesis and function of lipids
(microorganisms, rats)
ROlHL-06222-18 Clinical and laboratory studies in lipid
metabolism (human, mammals, non-human)
ROlHL-08634-15 Enzymic cholesterol synthesis (human,
rats, protozoa, yeast)
ROlHL-12745-10 Enzymes and inhibitors of cholesterol
biosynthesis (rats, human, swine)
ROlHL-15476-05 Mechanism and control of sterol
biosynthesis (rats)
ROlHL-20488-03 Cholesterol metabolism in diabetic man
TH(
TERPENES SAPONINS
** ROIHI 1658/04 Chole%lerol binding ttponini and
atheiosclerosn (monkeys)
TESTING OF INSTRUMENTATION, CLINICALLY
ORIENTED
SEE BIOMEDICAI ENGINffRING, INSIRUMENIAIION
ClINICAtlY ORIfNIfD
TESTING OF INSTRUMENTATION, NOT
CLINICAUY ORIENTED
SEE BIOMEDICAL ENGINEERING, INSTRUMENIAIION NOT
CLINICALLY ORIENTED
TESTOSTERONE
SEE ANOROSTANE SERIES. TESTOSTERONE
TESTS
SEE DIAGNOSIS, DIAGNOSTIC TESTS*
SEE HYPERSENSITIVITY TESTS
SEE IMMUNOlOGICAl TESTS AND IMMUNOASSAY,
IMMUNOLOGICAL TESTS-
SEE PSYCHOLOGICAL TESTS (GENERAL)*
TETANUS TOXOID
SEE IMMUNOLOGICAL PREPARATIONS, TOXOIDS, TETANUS
TOXOID
TETRACOSANOIC ACID
SEE FAHY ACIDS, TETRACOSANOIC ACID
TETRAETHYLAAAMONIUM COMPOUNDS
SEE AMMONIUM QUATERNARY, TETRAETHYLAMMONIUM
COMPOUNDS
TETRAETHYLENE PENTAMIN EPICHLORHYDRIN
COPOLYMER
SEE CHOLESTANE SERIES, CHOLESTEROL INHIBITORS,
COLESTIPOL
TETRAHYDROISOQUINOLINES
SEE QUINOLINES, ISOQUINOLINES
TETRALOGY OF FALLOT
SEE CONGENITAL ABNORMALITIES, HEART DEFECTS,
TETRALOGY OF FALLOT
TETRODOTOXIN
SEE TOXICOLOGY. ANIMAL POISONS. TETRODOTOXIN
THALAMUS
SEE BRAIN. THALAMUS
THALASSEMIA
SEE HEMOPROTEINS, HEMOGLOBINOPATHIES, THALASSEMIA
THALLIUM IMAGING
SEE HEART VISUALIZATION*
THALLIUM RADIOISOTOPES (198,202,204)
SEE RADIOISOTOPES, THALLIUM
THEOPHYLLINE
SEE PURINES, XANTHINES, THEOPHYLLINE
THERAPEUTIC DIET
SEE NUTRITION, DIET THERAPEUTIC
THERAPEUTIC EMBOLIZATION
SEE CARDIOVASCULAR SURGERY, VASCUUR OCCLUSION
THERAPEUTIC
THERAPEUTIC EQUIVALENCE OF DRUGS
SEE DRUGS, PHARMACOLOGY, BIOAVAILABILITY
THERAPEUTIC VASCULAR OCCLUSION
(OBLITERATION)
SEE CARDIOVASCULAR SURGERY, VASCULAR OCCLUSION
THERAPEUTIC
THERAPY, BURN THERAPY
ROlHL-20177-02 Effects of erythrocyte deformability on
tissue perfusion (rats)
THERAPY, CAUTERY, PHOTOCOAGULATION
THERAPY
P60HL-15168-07 0005 Comprehensive sickle cell disease
center - Ophthalmology (human, rabbits, monkeys)
POlHL-21016-02 0016 Sickle cell anemia and other
hemoglobinopathies - The treatment of sickle cell
retinopathy (human)
THERAPY, HYDROTHERAPY
** ROlHL-17407-05 Peripheral circulation and fluid balance
(fish, mammals, human)
THERAPY, INHALATION THERAPY
SEE ALSO DOSAGE AND ROUTE, INHAUTION
SEE ALSO RESPIRATORY ASSIST AND OXYGEN
ADMINISTRATION, AEROSOL THERAPY
SEE ALSO RESPIRATORY ASSIST AND OXYGEN
ADMINISTRATION, HYPERBARIC OXYGENATION
SEE ALSO RESPIRATORY ASSIST AND OXYGEN
ADMINISTRATION, OXYGEN INHALATION THERAPY
ROlHL-10622-12 Volumes and compliance of pulmonary
circulation (human, dogs)
(contd)
'Excludes routine methodotogy OR covers only general projects which preclude
**Oriented significantly to above subject.
indexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
THE
506
THE
THERAPY, LAVAGE
SEE ALSO BLOOD TREATMENT, WHOLE BODY PERFUSION
(BLOOD REPLACEMENT)
SEE ALSO RESPIRATORY ASSIST AND OXYGEN
ADMINISTRATION, PULMONARY LAVAGE
R23HL-19584-01 Alveolar macrophage responses to toxic
particle exposure (guinea pigs, human)
NOlHR-52957-02 Composition of respiratory mucus
(human, swine)
THERAPY, PLACEBO EFFECT
ROlHL-16651-05 Evaluation of steroid therapy in
sarcoidosis (human)
THERAPY, RELAXATION
SEE PSYCHIC ACTIVITY LEVEL, RELAXATION
THERAPY EVALUATION
*• NOlHB-22919-08 Hemoglobin carbamyiation in the
treatment of sickle cell anemia (human, dogs)
•* NOlHB-22922-08 Develop effective therapy for sickle cell
disease (human, dogs)
NOlHB-62970-02 Collection, function and transfusion of
Collection, function and transfusion of
granulocytes
NOlHB-6297305
granulocytes
NOlHB-7291602 Crisis and pain symptom prophylaxis by
oral zinc therapy (human)
R01HL01601-30 Blood coagulation and hemorrhagic
disease (horseshoe crabs)
■ POlHL-04664-18 0014 Cardiovascular and lung dynamics
- Clinical application of computer analysis of ventricular
wall motion
R01HL0466619 Artificially paced hearts -Technology,
physiology (human, dogs)
R01HL-05875-I8 Pathologic metabolic and physiologic
studies of heart (human, dogs, cats)
■ POlHL-06308-18 0029 Mechanisms and therapy of
circulatory disease - Characterization of the patient with
recurrent ventricular arrhythmias
POlHL-0631217 0013 Surgical cardiology - Aortocoronaiv
vein bypass grafting (human)
POlHL-06312-17 0016 Surgical cardiology ■ Effect of
hydralazine on infarct size following coronary occlusion
(human)
POlHL-06312-17 0017 Surgical cardiology ■ Cardiac
transplantation (human)
■ P01HL06312-17 0051 Surgical cardiology ■ Diuretic
therapy on myocardial electrolyte composition and water
content (human)
POlHL-06370-17 0001 Cardiopulmonary and renal
pathology research center - The humoral and cellular
mechanisms of allograft rejection (monkeys)
POlHL-0637017 0014 Cardiopulmonary and renal
pathology research center - Quantitative morphology in
cardiac disease (human, rats, dogs)
POlHL-0666417 0010 Cardiopulmonary function in
remediable vascular disease - Ischemia and acute renal
failure (rats)
P01HL0666417 0036 Cardiopulmonary function in
remediable vascular disease - In vitro studies on the
mechanism of ischemic damage to cells (rabbits)
■ P01HL06835-17 0053 Cardiovascular disease •
Vasodilating drugs (human)
ROlHL-07776-15 Sudden death and cardiac arrhythmias
(human, dogs, cats)
■ P01HL07896-15 0046 Environmental biomedical research
program - Treatment of radiation induced tissue injury by
hyperbaric oxygen (human)
POlHL-07896-15 0057 Environmental biomedical research
program - Effects of dipyridamole and aspirin on
decompression thrombocytopenia (human)
ROlHL-08888-12 Cooperative study of drugs and coronary
heart disease (men)
ROlHL-08892-10 Cooperative study of drugs and coronary
heart disease
POlHL-09011-15 0020 A research and resource program
in blood ■ Passive immunization in the prevention of
transmission of hepatitis B (human)
P01HL-0901M5 0023 A research and resource program
in blood ' Evaluation of hepatitis B vaccine in endemic
settings (human)
R0IHL-09474-I1 Natural history-congenital heart defects-
Joint study (human)
R01HL-a947610 Natural history, congenital heart defects-
Joint study
R01HL09914-13
(dogs, monkeys)
ROlHL-1044509
heart disease (men)
P01HLI0539-12 0023 Pathophysiology of circulation •
The relaxation response and therapy of disease states
(human)
POlHL-10539-12 0031 Pathophysiology of circulation -
Post myocardial infarction care -Psychological aspects
(human)
ROlHL-1058212 Thrombosis and hemostasis -Analysis,
methods and standards (human, cattle, venom)
R01HL10705-09 Cooperative study of drugs and coronary
heart disease (men)
ROlHL-10711-12 Cooperative study of treatment of
hypertension (human)
The myocardium in diabetes mellitus
Cooperative study of drugs and coronary
ROlHL-1071810 Natural history of congenital heart
defects -Joint study (human)
POlHL-11310-12 0059 Mechanisms of cardiovascular
disease - Contractility -Acute response to diogoxin after
heart surgery (children)
POlHL-1131012 9001 Mechanisms of cardiovascular
disease - Core support-hospital beds
ROlHL-11372-08 Cooperative study of drugs and coronary
heart disease (men)
P01HL-11414I1 0004 Thrombosis and atherosclerosis
program - Platelet function and nonthrombogenic surfaces
(human)
ROlHL-11775-11 Platelet mechanisms in disease (human,
primates)
POlHL-12738-10 0001 Physiologic pharmacology and its
clinical applications - Clinical pharmacology of cardioactive
drugs (human)
POlHL-1273810 0065 Physiologic pharmacology and its
clinical applications - Psychotheropeutic drugs and
cardiovascular system (human, rats)
P01HL12738-10 0076 Physiologic pharmacology and its
clinical applications - Pediatric cardiac electrophysiology
and pharmacology (human, dogs)
POlHL-12738-10 0092 Physiologic pharmacology and its
clinical applications - Subendocardial ischemia following
open heart surgery (human)
POlHL-131 08-09 0001 Clinical heart transplantation -
Therapy and prognosis (human)
POlHL-13108-09 0015 Clinical heart transplantation ■
Antithymocyte globulin analysis and clinical effects
POlHL-13108-09 0018 Clinical heart transplantation -
Electrophysiologic studies of cardiac drugs in the
denervated heart
R01HL13654-08 Antilipemic regimes in peripheral
arteriosclerosis (human)
P01HL13737-07 0028 Assisted circulation - Clinical
studies of intraaortic balloon pumping
POlHL-13737-07 0029 Assisted circulation ■ Chronic left
ventricular failure (human)
POIHL-1373707 0037 Assisted circulation - Clinical
measurement of blood flow through aortocoronary vein
bypass graft
R01HL1375408 Postoperative thromboembolism in
surgical patients (human)
ROlHL-1388508 0005 Cystic fibrosis and pulmonary
disease - Evaluation of lobar pulmonary lavage (human)
P5OHL14138-05 0010 Center for research on
atherosclerosis - Diet and exercise as therapy in men with
premature atherosclerosis
P50HLI419208 0001 Specialized center of research in
hypertension - Surgical and medical treatment of
renovascular hypertension (human)
P50HL-I4 192-08 0002 Specialized center of research in
hypertension ■ Hypertensive patients with renal artery
stenosis
P50HL-14217-08 0049 Specialized center of research in
thrombosis • Fibrinolysis section -Clinical studies
P50HL-14236-05 Prevention of premature arteriosclerosis
P50HL14236-05 0002 Prevention of premature
arteriosclerosis - Myocardial blood flow in patients with
coronary artherosclerosis
P50HL-14236-05 0009 Prevention of premature
arteriosclerosis - Clinical studies on cholesterol metabolism
(human)
P50HL-14237-07 0006 Support for arteriosclerosis center
- Drug treatment of familial hyperbetallpoproteinemia
(human)
ROlHL-14378-07 Lipemias and reconstructive cardiac
surgery (human)
ROlHL-14663-07 Pulmonary oxygen toxicity in newborn
lung (human, mice)
ROlHL-147 17-06 Hemodynamics and heart structure-
Ventricular overload (dogs)
POlHL-14985-07 0013 Adaptation to hypoxia - Chronic
mountain sickness (men)
P50HL-15061-07 0013 Response of lung to injury -
Exchange transfusion in infants with respiratory distress
syndrome (human, sheep)
P60HL151 58-07 0011 Comprehensive sickle cell center -
Clinical services -Adult patients
P60HL-1516007 0014 Center for sickle cell disease -
Replacement therapy of opsonin deficiency in sickle cell
anemia (children)
P60HL-151 62-07 0021 Comprehensive sickle cell center -
Pneumococcal vaccine in sickle cell disease (children)
P60HL-15169-05 0018 Support for center for sickle cell
disease - Studies on sickle cell disease (human, rats,
dogs)
P60HL 15170-05 0001 Support for center for sickle cell
anemia - Adult clinical services
R01HL15190-07 Physiological basis of arrhythmias and
their therapy (human)
POlHL-15265-05 Program on surgical control of the
hyperlipidemias
POlHL-15265-05 0013 Program on surgical control of the
hyperlipidemias - Clinical center • Minnesota
POIHL-15265-05 0014 Program on surgical control of the
hyperlipidemias - Arkansas clinical center
ROlHL-153 74-03 Cooperative study of drugs and coronary
heart disease (human)
ROlHL-15526-05 Respiratory mechanics in children
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
**Onented significantly to above subject.
ROlHL-15758-06 Catecholamine release in the heart
(dogs)
P60HL-1599606 0003 Cincinnati comprehensive sickle
cell center - Prophylactic penicillin in treatment of sickle
cell anemia (human)
P60HL- 15999-05 0008 Miami comprehensive sickle cell
center - Cyanate effect on host defense -Cellular and
humoral (human, guinea pig, rabbits)
P60HL16005-05 0021 Comprehensive sickle cell center -
Management of pregnancy in sickle cell anemia (human)
P60HL-16008-06 0015 Wayne State University
comprehensive sickle cell center - Trace elements In sickle
cell disease (human)
R01HL16375-04 Investigation of hemoglobin S properties
(human)
ROlHL-16412'04 Release of nucleosides from the Ischemic
heart (human, dogs)
R01HL16461-05 Late results of valve replacement-
Computer analysis (human)
R0!HL'16651-05 Evaluation of steroid therapy in
sarcoidosis (human)
R01HL-167S7 04 Autoimmune' thrombocytopenia (monkey)
ROIHL 17243-05 Cause of chronic experimental renal
hypertension (dogs, rabbits)
P60HL-17265-04 0006 Community blood resource center
support - Research -Evaluation of platelet transfusions
(human, dog)
P60HL17265-04 0007 Community blood resource center
support Research -Massive transfusion and trauma
(human)
P60HL-17265-04 0009 Community blood resource center
support ■ Research -Developing granulocyte transfusion
therapy (human, rabbit)
P60HL-1 7269-04 0029 National heart and blood vessel
research and demonstration center - Clinical application of
circulatory assistance (human)
P60HL- 17292-04 0009 Vermont Lung Center ■ Controlled
clinical trials on a clinical core unit (human)
ROlHL-17513-04 Role of PF-4 in detecting and promoting
thrombosis (human, primates)
ROlHL-17631-05 Experimental congestive heart failure and
hypertrophy (cats)
P50HL-1 7646-04 0001 Study of ischemic heart disease ■
Core clinical investigation unit
P50HL-1 7646-04 0015 Study of ischemic heart disease -
Protecting ischemic myocardium In patients with evolving
myocardial infarction
P50HL 17648-04 0011 Study of Ischemic heart disease -
Surgical treatment for acute myocardial ischemia (human,
dogs)
P50HL-1 7648-04 0012 Study of ischemic heart disease -
Retrograde coronary venous pertusion-Acute myocardial
ischemia
P50HL-17651-04 0032 Ischemic heart disease specialized
center of research - Cardiovascular surgery core (human,
dogs)
P5aHL-17655-04 Study of ischemic heart disease
P50HL1765504 0001 Study of ischemic heart disease -
Intravenous nitroglycerin-Ventricular function and infarct
size (human, dog)
P50HL-17655-04 0003 Study of ischemic heart disease ■
Cardiopulmonary resuscitation (human, dog)
P50HL17655-04 0006 Study of ischemic heart disease ■
Evaluation of coronary artery bypass graft surgery (human)
P50HL-17655-O4 0009 Study of ischemic heart disease •
Random trial of medical and surgical therapy in unstable
angina (human)
P50HL-17665-04 Study of ischemic heart disease
P50HL-1766504 0001 Study of ischemic heart disease -
Reduction of acute anterior myocardial infarction-
Mechanical circulatory assist
P50HL-17665-04 0002 Study of ischemic heart disease ■
Reducing acute anterior myocardial infarction-Beta
adrenergic blockade (human)
P50HL-17665-04 0003 Study of ischemic heart disease ■
Quantitation of injury-Acute myocardial infarction
complicated by shock (human)
P50HL-17665-04 0013 Study of ischemic heart disease -
National cooperative study in unstable angina pectoris
(human)
P50HL-1766504 0020 Study of ischemic heart disease ■
Ischemic injury to myocardium during measured states of
ischemia (human)
P50HL17665-04 0022 Study of ischemic heart disease -
Effect of coronary revascularization on left ventricular
function (human)
P50HL- 17665-04 0026 Study of ischemic heart disease ■
Anesthesia-Myocardial ischemia and hemodynamics in
coronary disease (human)
P50HL17667-04 0001 Study of ischemic heart disease -
Natural history of ischemic heart disease (human)
P50HL-17667-04 0018 Study of ischemic heart disease -
Arrhythmias in ischemic heart disease (human)
P50HL-1766704 0019 Study of ischemic heart disease -
Assessment of long-term results of coronary artery bypass
grafting (human)
P50HL-17667-04 0022 Study of ischemic heart disease ■
Preventing myocardial injury in surgery using
cardiopulmonary bypass (human, rat)
P50HL-17669-04 0012 Ischemic heart disease center
(SCOR) - Circulatory assistance (human, dog)
P50HL-17670-04 Study of ischemic heart disease
(contd)
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
THI
** P50Hl'17670 04 0008 Study ol IscKemic heart diseasa
Surgical traatmeni ot cardiac rhythm disorders (human,
dots)
P50HL 17670 04 0009 Study ol ischemic heart disease
Surgical treatment ol localised lett ventricular dyssyncrgy
(human, dogs)
** P50HL 17682 04 0001 Study ol ischemic heart disease
Studies in acute and chronic ischemic heart disease
(human)
" P50HI 17682 04 0003 Study ol ischemic heart disease
tttects ol myocardial revascularliation in man
** P50HL17682 04 0008 Study of ischemic heart disease •
Clinical core unit
P50HL 17682 04 0016 Study of ischemic heart disease •
Endurance exercise Prevention and rehabilitation in
ischemic heart disease (pig)
POIHL 17731 04 0006 Physiological basis of pulmonary
disease Ventilationperfusion ratios (human, dogs)
ROIHL 1774903 Adrenocortical factors in human
hypertension (human)
ROIHL 17776 04 Pulmonary mucus transport in
obstructive lung diseases (human)
POIHL'17871'04 0009 Kidney, sodium, cardiac output,
arterioles and hypertension - Kidney, sodium, cardiac
output, arterioles and hypertension
ROIHL 1787304 Pathophysiology of exercise-induced
asthma (human)
R01HL1790904 Drug treatment of vascular scleroprotein
defects (human, turkeys)
R01HL17974-03 External pneumatic compression in deep
venous thrombosis (human)
M R01HL1799304 Ventricular dynamics from surgically
inserted markers
R01HL1799304 0001 Ventricular dynamics from
surgically inserted markers - Effects of aortocoronary
bypass graft surgery on ventricular function (human)
ROIHLI 7993-04 0003 Ventricular dynamics from
surgically inserted markers - Effects of pharmacologic
agents on lett ventricular dynamics (human)
ROlHL-1799304 0005 Ventricular dynamics from
surgically inserted markers - Cardiac dimensions and
dynamic after mitral, aortic valve surgery (human)
R01HL18190-03 Myocardial blood flow in acute
myocardial infarction (human, dogs)
R01HL18204-03 Regional blood flow in viral myocarditis
(turkeys)
ROlHL-18308-03 Comprehensive studies of mucociliary
transport (dogs)
P50HL-18323-04 0043 SCOR hypertension center -
Pharmacology-Renin-aldosterone mechanisms in essential
hypertension (human)
P50HL-18323-04 0047 SCOR hypertension center -
Transcendental meditation and self-hypnosis-Hypertension
treatment (human)
ROlHL-18333-05 Thrombogenesis and hemostatic balance
(rabbits, human)
ROlHL-18467-03 Fingertip blood flovi in normals and
Raynaud's disease (human)
POlHL-18576-03 0012 Thrombosis research program
project - Synthetic anticoagulant and thrombolytic agents
(dogs)
ROlHL-18606-04 Pathogenesis and measurement of
pulmonary edema (human, rabbits, dogs)
POIHL- 18646-03 0009 Studies basic to heart
transplantation - Pathologic aspects of cardiac allograft
rejection (sheep, dogs)
POlHL-18708-03 0010 Oxygen, energy and contractility in
cardiac tissue - Tissue oxygen utilization (rats, dogs)
ROlHL-18738-02 Prevention of postoperative venous
thrombi (human, cattle)
ROlHL-18783-04 Detection and control of ventricular
premature beats (human)
ROlHL-18805-04 0003 Sudden cardiac death and the
onset of myocardial infarction - Prediction from clinical and
laboratory assessments (human)
ROlHL-18805-04 0004 Sudden cardiac death and the
onset of myocardial infarction - Sudden death survivors-
Clinical follow-up and therapy (human)
ROlHL-18814-03 Behavioral tactics for clinical cardiac
control (human)
** R01HL18907-03 Objective evaluation early after Ml and
heart surgery (human)
ROlHL-18997-02 Ischemic therapy in experimental
hypersplenism (rats, dogs)
ROlHL-19045-03 Electrophysiology of cardiac aufomaticity
(human, dogs)
P50HL-19170-02 0007 Harvard pulmonary SCOR -Chronic
diseases of the airways - Therapy effect on airway
obstruction in acute asthma (human)
** P50HL-19185-02 0007 Pulmonary SCOR-Neonatal
respiratory distress syndromes • Sodium bicarbonate and
albumin in resuscitation of preterm infants (human)
** P50HL-19185-02 0009 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Nasal continuous positive
ain«ay pressure in hyaline membrane disease (human)
♦* P50HL-19187-02 0010 Pediatric pulmonary SCOR -Hyaline
membrane disease - Treatment, outcome of HMO-
Continuous positive airway pressure (human, monkey)
POlHL-19259-03 0004 Digoxin-specific antibody in human
therapy - Digitalis-specific antibodies pharmacological
studies (human, dogs, sheep)
507
ROIHL 194bl 03 0004 lunclional chaiaclcnslics ol the
left heart Quantitative coronary arteriography (human)
** ROIHL 19!)68 03 Hypertension Analysis ol drug and
behavioral therapies (human)
•* POIHL 197 W 02 0040 Response ol the lung to in|ury
Immunosuppressive drugs in usual interstitial pneumonia
(human)
ROIHL 19844 02 Behavioral control of essential
hypertension (human)
ROIHL 19946 03 Reduction ot iron overload in
thalassemia (children, rabbits, dogs, monkeys)
ROIHL 19961-03 Management ot hemosiderosis in
thalassemia (children, adults)
ROIHL 20016 03 Chelator development for thalassemia
(human, mice. rats. dogs, monkeys)
** ROIHL 20187-01 Evaluation of exercise cardiac
rehabilitation program (40 55 year old men)
R01HL2019002 Pathogenesis of cardiac hypertrophy
(dogs)
ROIHL 20218-02 Fibrinogen catabolism and intravascular
coagulation (human)
ROlHL-20286 02 Interventions to improve cardiac function
in ischemia (dogs)
** R01HL20337 02 Thromboembolic diseases (human)
ROlHL-20394-03 Complement activation by heart
subcellular membranes (human, dog)
ROlHL-20397-03 VLDL-TG metabolism in diabetes mellitis
(human, rat)
" ROlHL-20455-03 Role of systemic hypertension on diabetic
retinopathy (human)
M POlHL-20552-02 The development and regression of
cardiac hypertrophy
POlHL-20552-02 0002 The development and regression of
cardiac hypertrophy - Effect of treatment on the
hypertrophied lett ventricle (rats)
ROlHL-206 12-02 Chronic animal model of pulmonary
vascular injury (dogs)
** ROIHL 20856-02 Platelet transfusions-Usage and
complications (human)
" P60HL-20985-01 0002 Northern California sickle cell
center - Immunization with polyvalent pneumococcal
polysaccharide vaccine (human)
P50HL-2 1006-02 0001 Specialized center of research in
arteriosclerosis - Clinic and core program
POlHL-210 16-02 0016 Sickle cell anemia and other
hemoglobinopathies - The treatment of sickle cell
retinopathy (human)
ROlHL-21052-01 Evaluation of a digitalis therapy advisor
** ROlHL-21 115-01 Prevention of 02 toxicity with superoxide
dismutase (rats)
** ROlHL-21293-02 Randomized study of coronary bypass
surgery (human)
ROlHL-21323-02 Raynaud's disease and temperature self-
regulation (human)
ROIHL-21427-02 Behavioral changes in post infarction
patients
ROlHL-2 1444-02 Pulmonary mechanics during postnatal
development (human)
" ROlHL-21533-02 Platelet inhibitor drug in coronary surgery
(human)
R23HL-22004-01 Imaging and ECG studies in acute and
chronic IHD (human)
ROlHL-22026-01 Endogenous prostaglandins in asthma
ROlHL-22035-01 Molecular modification of heparin by
chemical means (sheep)
ROlHL-22065-01 Intractability, medication, and coping
styles in asthma (human)
" ROlHL-222 15-01 Effects of exercise-training in ischemic
heart disease (human)
M R23HL-22345-02 Behavioral cardiovascular compliance
strategies
ROlHL-22547-01 Behavioral treatment of Raynaud's
disease (human)
R23HL-22575-01 Factors modifying cardiac digoxin effects
and content (dogs, cats)
** ROlHL-22750-01 Digoxin in heart failure with sinus
rhythm (human)
ROlHL-22843-01 Pulmonary physiology in liquid ventilation
(lambs)
ROlHL-22868-01 Presynaptic regulatory mechanisms in
hypertension (rats, dogs)
** ROlHL-22875-01 Crotalase-Chemistry, physiology, clinical
potential (rats, rabbits)
** R18HL-22934-D1 Behavorial approaches to adolescent
hypertension
** P60HL-23282-01 0003 Comprehensive hospital/community
sickle cell center - Treatment of sickle cell ulcers with
physical therapy and vitamin E (human)
** NOlHR-62942-04 Nocturnal oxygen therapy in chronic
hypoxic lung disease (humam)
** NOlHR-62943-05 Nocturnal oxygen therapy in chronic
hypoxic lung disease (human)
" NOlHR-62944-04 Nocturnal oxygen therapy in chronic
hypoxic lung disease (human)
** NOlHR-62945-04 Nocturnal oxygen therapy in chronic
hypoxic lung disease (human)
** NOlHR-62946-04 Nocturnal oxygen therapy in chronic
hypoxic lung disease (human)
** NOlHR-62947-04 Nocturnal oxygen therapy in chronic
hypoxic lung disease (human)
** NOlHR-62948-04 Evaluate antenatal steroid therapy in
neonatal respiratory distress syndrome
THE
*• N01HR629490b Ivaluale »nlen«l«l •.lefoid Ihnapy in
neonatal respiratory dislre\% jyndrome
" NOIHR 62950 04 Evaluate antenatal steroid Iherapy in
neonatal respiratory distress syndrome
•• NOIHR 62951 04 Evaluate antenatal steroid therapy in
neonatal respiratory distress syndrome
•• NOIHR 62952 05 Evaluate antenatal steroid therapy in
neonatal respiratory distress syndrome
** NOIHR 72902 04 Study ol intermittent positive pressure
breathing
•* NOIHR 72903 05 Study ol intermittent positive pressure
breathing
*• NOIHR 72904 03 Study ol intermittent positive pressure
breathing
** NOIHR 72905 03 Study ol inteimitteni positive pressure
breathing
*• NOIHR 7290603 Study ol intermittent positive pressure
breathing
•* NOIHR 72972 01 Sell management lor asthmatic children
•• NOIHV 12434-11 Therapy for hypertension in the general
population
•• NOIHV 12435-15 Therapy for hypertension in the general
population (human)
•* NOIHV 12436-15 Hypertension therapy in the general
population (human)
** NOIHV 12440-14 Therapy lor hypertension in the general
population (human)
" NOIHV 12442-14 Therapy lor hypertension in the general
population (human)
** NOlHV-22931-14 Therapy lor hypertension in general
population
** NOlHV-22937-07 Therapy lor hypertension in general
population
** NOlHV-22938-11 Therapy lor hypertension in general
population
NOlHV-22939-12 Hypertension detection and lollow-up
program center
** NOlHV-22945-11 Cooperative hypertension detection and
lollow-up study (human)
NOlHV-22971-07 Prevention of coronary heart disease
(human)
NOlHV-22976-07 Multiple risk factor intervention trial.
prevention ol coronary heart disease
NOlHV-22977-08 Intervention trial lor the prevention ol
coronary heart disease (human)
NOlHV-22979-07 Intervention trial lor the prevention ol
coronary heart disease (human)
NOlHV-22980-06 Intervention trial lor the prevention ol
coronary heart disease (human)
NOlHV-22981-10 Intervention trial lor the prevention ol
coronary heart disease (human)
NOlHV-22982-07 Intervention trial for prevention of
coronary heart disease (human)
NOlHV-22983-07 Intervention trial lor the prevention of
coronary heart disease (human)
NOlHV-32973-12 Coordinating center for collaborative
studies on coronary artery surgery
NOlHV-32974-09 Collaborative studies on coronary artery
surgery (human)
NOlHV-32975-08 Collaborative studies on coronary artery
surgery (human)
NOlHV-32976-09 Collaborative studies on coronary artery
surgery (human)
NOlHV-32980-07 Collaborative studies on coronary artery
surgery (human)
NOlHV-32981-10 Collaborative studies on coronary artery
surgery (human)
NOlHV-32983-11 Collaborative studies on coronary artery
surgery (human)
N01HV-32984-10 Collaborative studies on coronary artery
surgery (human)
NOlHV-32985-11 Collaborative studies on coronary artery
surgery (human)
NOlHV-33101-06 Development and conduct of a multiple
risk factor intervention trial (human)
NOlHV-33105-09 Intervention trial for prevention of
coronary heart disease (human)
NOlHV-33106-06 Intervention trial lor the prevention of
coronary heart disease (human)
NOlHV-33108-04 Prevention ol coronary heart disease
(human)
NOlHV-33109-04 Intervention trial for the prevention of
coronary heart disease (human)
NOlHV-33110-04 Prevention of coronary heart disease
(human)
NOlHV-42929-08 Risk factor intervention trial lor the
prevention ol CHD (human)
NOlHV-42930-09 Risk lactor intervention trial for the
prevention ot CHD (human)
NOlHV-42931-07 Risk lactor intervention trail lor the
prevention ol CHD (men)
** NOlHV-52901-06 Aspirin-myocardial infarction study
" NOlHV-52941-04 Center for aspirin-myocardial infarction
study (human)
** NOlHV-62960-00 Techniques to protect ischemic
myocardium and minimize inlant size (human)
NOlHV-72940-02 Therapy to protect ischemic myocardium
(human)
NOlHV-72941-02 Therapy to protect ischemic myocardium-
Clinical tests
NOlHV-72942-02 Therapy to protect ischemic myocardium-
Clinical tests
(contd)
'Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
"Onented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
THE
508
THY
NOlHV-72948-03 Coordinating center for propranolol heart
trial (human)
NOlHV-72951-03 Clinical center for propranolol heart trial
(human)
NOlHV-72952-02 Clinical center for propranolol heart trial
(huamn)
** NOlHV-72953-04 Clinical center for propranolol heart trial
NOlHV-72954-06 Clinical center for propranolol heart trial
(human)
NOlHV'72955-02 Clinical center for propranolol heart trial
(human)
N01HV-7295e-02 Clinical center for propranolol heart trial
(human)
NOlHV-72957-02 Clinical center for propranolol heart trial
(human)
** NOlHV-72958-02 Clinical center for propranolol heart trail
(human)
NOlHV-72959-04 Clinical center for propranolol heart trial
(human)
** NOlHV-72960-02 Clinical center propranolol heart trial
(human)
** NOlHV-72963-02 Clinical center for propranolol heart trial
(human)
** NOlHV-7296402 Clinical center for propranolol heart trial
(human)
** NOlHV-72967-02 Clinical center for propranolol heart trial
(human)
NOlHV-7296902 Clinical center for propranolol heart that
(human)
** NOlHV-82904-02 Clinical center for propranolol heart trial
(human)
" NOlHV-8291000 Clinical center for propranolol heart trial
(human)
** NO IHV'829 15-01 Therapy for hypertension in the general
population (human)
THERMOACTINOMYCES
SEE BACTERIA, ACTINOMYCETALES, THERMOPHILIC
ACTINOMYCETES*
THERAAODYNAMICS (CHEMISTRY)
SEE CHEMISTRY, THERMODYNAMICS (GENERAL)
THERMOGRAPHY
SEE TEMPERATURE MEASUREMENT, THERMOGRAPHY*
THERMOLYSIN
SEE PROTEASES AND PEPTIDASES, THERMOLYSIN
THERMOPHILIC ACTINOMYCETES
SEE BACTERIA, ACTINOMYCETALES, THERMOPHILIC
ACTINOMYCaES*
THERMOPOLYSPORA
SEE BACTERIA, ACTINOMYCETALES, THERMOPHILIC
ACTINOMYCETES*
THERMORECEPTION
SEE SENSORY-PERCEPTUAL PROCESSES, THERMORECEPTION
THERMOREGULATION (BODY TEMPERATURE)
SEE TEMPERATURE (BODY) REGULATION
THERMOSTABILITY-LABILITY
SEE TEMPERATURE, HEAT STABILITY-LABILITY
THIADIAZINES, DIAZOXIDE
POlHL-06835-17 0053 Cardiovascular disease -
Vasodilating drugs (human)
ROIHL-1282708 Regulation of sodium excretion (dogs,
rats)
THIAMINE DEFICIENCY
SEE NUTRITIONAL ABNORMALITIES, HYPOVITAMINOSIS B,
THIAMINE DEFICIENCY
THIAZINES
SEE ALSO PHENOTHIAZINES
R01HL1770204 Electro-optical dyes as probes of heart
excitability
THIN LAYER CHROMATOGRAPHY
SEE PHYSICAL SEPARATION, CHROMATOGRAPHY, THIN
LAYER*
THIOCARBAMATES, DISULFIRAM
ROlHL-22718-01 Cardiovascular drug interactions-
Metabolism models (dogs)
THIOCARBAMIDE
SEE THIOUREA
THIOCTIC ACID
SEE VITAMIN B, LIPOIC ACID
THIOCYANATES
ROlHL-14127-16 Methemoglobinemia and antihypertensive
drugs (cats, mice, rats)
P50HL-1936202 0006 A/S SCOR -Atherosclerosis in
nonhuman primates - Effects of cigarette smoking on
atherosclerosis (baboon)
THIODIPHENYLAMINE
SEE PHENOTHIAZINES
6-THiOGUANOSINE
SEE THIOPURINE NUCLEOSIDES, THIOGUANINE NUCLEOSIDES,
6 THIOGUANOSINE
THIOLS
SEE ALSO SULFHYDRYLS
P50HL-14217-08 0C58 Specialized center of research in
thrombosis - Mechanisms of induction and inhibition of
platelet reaction (human, pig)
M PClHL-16683-04 Function and growth of cardiac and
skeletal muscle
POlHL-16683-04 0001 Function and growth of cardiac
and skeletal muscle Light chains of the skeletal and
cardiac myosin molecule (rabbits, frogs)
POIHL- 166 83-04 0002 Function and growth of cardiac
and skeletal muscle - Myosin, actin, ATP, interaction In
solution
** POlHL-16683-04 0003 Function and growth of cardiac
and skeletal muscle - Movements of S-1 moieties in muscle
fibers
POlHL-16683-04 0006 Function and growth of cardiac
and skeletal muscle - Chemical studies of the contractile
system -Development of new reagents
POlHL-20984-02 0003 Cellular mechanisms in cardiac
hypertrophy - Fast-kinetics of myosin ATPase from normal
and hypertrophied heart (rabbits)
THIOPENTAL
SEE PYRIMIOINES, BARBITURATES, THIOPENTAL
THIOPHENES
SEE ALSO SULFONATES, TRIMETHAPHAN CAMSYLATE
SEE ALSO VITAMIN B, BIOTIN
ROlHL-15512-06 Drug treatment of stenosing primate
atherosclerosis (rabbits, monkeys)
THIOPURINE NUCLEOSIDES, THIOGUANINE
NUCLEOSIDES, DEOXYTHIOGUANOSINE
ROlHL-208 56-02 Platelet transfusions-Usage and
complications (human)
THIOPURINE NUCLEOSIDES, THIOGUANINE
NUCLEOSIDES, 6-THIOGUANOSINE
ROlHL-20856-02 Platelet transfusions-Usage and
complications (human)
THIOPURINES, 6-MERCAPTOPURINE
POlHL-13108-09 0001 Clinical heart transplantation -
Therapy and prognosis (human)
THIOPURINES, 6-MERCAPTOPURINE,
AZATHIOPRINE
POlHL-063 12-17 0018 Surgical cardiology - Cardiac
transplantation growth (calves)
POlHL-06370-17 0004 Cardiopulmonary and renal
pathology research center - Lymphocytes in graft rejection
and immune surveillance (human)
ROlHL-08696-15 0012 Orthotopic heart transplantation -
Transplantation immunology-Modulation of donor
antigenicity (dogs)
POlHL-13108-09 0001 Clinical heart transplantation -
Therapy and prognosis (human)
POIHL- 13 108-09 0014 Clinical heart transplantation -
Platelets and coagulation in accelerated graft coronary
atherosclerosis
POlHL-13 108-09 0016 Clinical heart transplantation -
Total lymphoid irradiation for immune response (dogs)
POlHL-20993-02 0005 Population dynamics of arterial
cells in atherogenesis - Drugs other than hypolipidemic
drugs affecting atherosclerosis (swine, rabbits)
THIOPYRIMIDINES, THIOURACIL
ROlHL-02063-23 Biochemistry and function of lipids and
cell membranes (human, yeast, animals)
THIOSUGARS
SEE CARBOHYDRATES. SULFOSUGARS, THIOSUGARS
THIOURACIL
SEE THIOPYRIMIDINES, THIOURACIL
THIOUREA
R01HL19720-03 Evaluation of antifibrotic agents in
pulmonary fibrosis (rats)
THIRST
SEE NUTRIENT INTAKE ACTIVITY, THIRST
THOMSEN DISEASE
SEE METABOLIC DISORDERS INBORN, MYOTONIA CONGENITA
THORACIC DUCT
SEE BLOOD AND RE SYSTEM, LYMPHATIC CIRCULATION,
THORACIC DUCT
THORACIC PRESSURE
SEE RESPIRATORY FUNCTION, RESPIRATION. THORACIC
PRESSURE
THORACIC SURGERY
SEE SURGERY, THORACIC
THORAX
SEE BODY REGIONS, THORAX
THORAZINE
SEE PHENOTHIAZINES, CHLORPROMAZINE
THOUGHT CONTROL
SEE PSYCHOLOGY, BRAIN CONTROL
THREE-DIMENSIONAL X-RAY SCANNING
SEE RADIOGRAPHY, SCANNING, DSR
THRESHOLDS, SENSORY
SEE SENSORY THRESHOLDS
THROAT
SEE ORALPHARYNGEAL. PHARYNX
THROMBASE
SEE BLOOD COAGULATION. THROMBIN
THROMBASTHENIN
SEE BLOOD COAGULATION. THROMBOSTHENIN
THROMBIC INDEX
SEE BLOOD COAGULATION TESTS. THROMBIC INDEX*
THROMBIN
SEE BLOOD COAGUUTION. THROMBIN
THROMBOCYTE TYPING
SEE BLOOD PLATELET TYPING
THROMBOCYTES
SEE BLOOD PLATELETS
THROMBOCYTHEMIA, HEMORRHAGIC
SEE BLOOD PLATELETS DISORDERS. THROMBOCYTHEMIA,
HEMORRHAGIC
THROMBOCYTOPATHY
SEE BLOOD PUTELETS DISORDERS. THROMBOCYTOPATHY
THROMBOCYTOPENIA
SEE BLOOD PLATELETS DISORDERS. THROMBOCYTOPENIA
THROMBOCYTOPENIC PURPURA
SEE BLOOD PLATELETS DISORDERS, THROMBOCYTOPENIC
PURPURA
TH ROMBOEMBOLISM
SEE CARDIOVASCULAR DISORDERS, EMBOLISM.
THROMBOEMBOLISM
THROMBOLYSIS
SEE BLOOD COAGULATION. FIBRINOLYSIS
THROMBOPATHY CONSTITUTIONAL
SEE BLOOD COAGULATION DISORDERS, VON WILLEBRAND'S
DISEASE
SEE BLOOD PLATELETS DISORDERS. THROMBOCYTOPATHY
THROMBOPHLEBITIS
SEE CARDIOVASCULAR DISORDERS, THROMBOPHLEBITIS
THROMBOPLASTIN
SEE BLOOD COAGULATION, THROMBOPLASTIN
THROMBOPLASTINOGEN
SEE BLOOD COAGULATION, FACTOR IX
THROMBOPLASTINOGEN A
SEE BLOOD COAGULATION, FACTOR VIM
THROMBOPOIESIS INHIBITORS
SEE BLOOD COAGUUTION, THROMBOPOIESIS INHIBITORS
THROMBOPOIESIS STIMULATING FACTORS
SEE BLOOD COAGULATION. THROMBOPOIESIS STIMUUTING
FACTORS
THROMBOPOIETIN
SEE BLOOD COAGUUTION, THROMBOPOIESIS STIMUUTING
FACTORS, THROMBOPOIETIN
THROMBOSIS
SEE CAROIOVASCUUR DISORDERS, THROMBOSIS
THROMBOSIS, VENOUS (INCL. DEEP VEIN)
SEE CAROIOVASCUUR DISORDERS, THROMBOSIS, VENOUS
THROMBOSTHENIN
SEE BLOOD COAGUUTION, THROMBOSTHENIN
THROMBOXANES
SEE FATTY ACIDS, UNSATURATED FAHY ACIDS,
THROMBOXANES
THYMECTOMY
SEE BLOOD AND RE SYSTEM, THYMECTOMY
THYMIDINE FACTOR
SEE GROWriH HORMONES VERTEBRATE. SOMATOMEDIN
(SULFATION FACTOR)(THYMIDINE FACTOR)
THYMIDINE KINASE
SEE PHOSPHOTRANSFERASES, ATP:THYMIDINE 5-
PHOSPHOTRANSFERASE
THYMIN
SEE BLOOD AND RE SYSTEM, THYMOSIN
THYMOSIN
SEE BLOOD AND RE SYSTEM. THYMOSIN
THYMUS DEPENDENT IMMUNE SYSTEM
SEE IMMUNITY, CELLUUR IMMUNITY (GENERAL)
THYROCALCITONIN
SEE THYROID HORMONES, (THYROCALCITONIN
*Exctudes routine methodok)gy OR covers only general projects which preclude indexing
"Onented significantly to above subject
at the specific level.
M Grant has subprojeds describing specific research aspects.
See Appendix for investigator's name and grant number.
THY
THYROID ANTAGONISTS
ROIHI ?03b2 02 Defenses ot lun| cells against o«y|en
toxicity (human, animals)
THYROID FUNCTION
R01H10697S18 Pathogenesis and prevention ol
hypedension (lats)
ROIHI 1549806 Effects of pliysical training on heart
(rats)
ROlHl-2236101 Regulation of cardiac adaptation to
exercise (rats)
•* ROIHL 2311501 Regulation of active sodium transport
(frogs, rats)
THYROID GLAND DISORDERS
R01HL02063-23 Biochemistry and function of lipids and
cell membranes (human, yeast, animals)
•* P01HL06370 17 0015 Cardiopulmonary and renal
pathology research center ■ Pathogenesis of chemically
induced tissue injury (rats)
ROIHI. 2225801 New aspects of pharmacology related to
carbonic anhydrase
ROIHL 22354 01 Alpha adrenergic effects on heart
metabolism (rats)
ROlHL-22812 01 Regulation of hepatic production of HDL
(rats)
THYROID GLAND DISORDERS,
HYPERTHYROIDISM
R01HL1337509 Cellular potential changes causing
cardiac arrhythmias (dogs)
R01HL1363608 Effects of pharmacologic agents on heart
metabolism (human, rodents)
P01HL14388-07 0179 Regulation of the circulation in
pathological states ■ Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
P01HL14985-07 0012 Adaptation to hypoxia - Direct
effect ol hypoxia on pulmonary vascular smooth muscle
(rats, dogs)
R01HL1643604 Role of calcium and thyroxine in heart
function (rats)
ROlHL-20678-02 Cardiovascular adaptation to stress in
disease states (dogs)
POlHL-20984-02 0001 Cellular mechanisms in cardiac
hypertrophy - Contractile proteins in cardiac hypertrophy
(rabbits, calves)
POlHL-2098402 0003 Cellular mechanisms in cardiac
hypertrophy ■ Fast-kinetics of myosin ATPase from normal
and hypertrophicd heart (rabbits)
THYROID GLAND DISORDERS, HYPOTHYROIDISM
R01HL02965-22 Metabolism of plasma lipoproteins (rats,
chickens, human)
ROIHL 1362606 Lipoprotein lipase and lipoprotein
removal (human, rats, bacteria)
P01HL18574-03 0006 Lipoprotein methodology and
biomedical applications ■ Lipoprotein transformation,
lipolytic enzymes, diet and lipid lowering agents
ROlHL-22873-01 Adrenoceptor intcrconversion and
hormone homeostasis
THYROID HORMONES
SEE ALSO THYRONINE. TRIIODOTHYRONINE
R01HL-01813-25 Regulation of metabolism by drugs and
hormones (rats)
" POlHL-06285-18 0195 Cardiovascular-respiratory
physiology and biochemistry - Thyroid thermogenesis and
sodium transport (rats)
ROlHL-06924-16 Humoral and metabolic aspects of
cardiac function (mammals, non-human, human)
P01HL-14388-07 0191 Regulation of the circulation in
pathological states - Regulation of chloride transport in
epithelial membranes (turtles)
R01HL14706-07 Fetal hearts in organ culture (mice)
ROlHL-16611-04 Digitalis-receptor of the heart (guinea
pigs, rats)
ROlHL-1676005 Dynamic control of coronary blood flow
(dogs)
R01HL18003-05 Digitalis-Mechanism and reversal studies
(dog, sheep, duck, guinea pig. human)
** ROlHL-18176-02 Effect of thyroid hormone on cultured
cardiac cells (rats)
ROlHL-18185-04 Cardiac glycosides and diuretics-Role of
NaO pump (dogs)
ROlHL-18553-03 Membrane defects in familial
hypercholesteremia (human)
P01HL18645-03 0007 Biology of the artery wall and
atherosclerosis - Lipoprotein metabolism in subhuman
primates
ROlHL-19010-03 Metabolism and cell biology of lung
surfactant system (rabbits, sheep)
POlHL-20552-02 0001 The development and regression of
cardiac hypertrophy ■ Biochemical events in cardiac
hypertrophy (rats)
POlHL-20592-02 0010 Cell biology of cardiac and
skeletal muscle - Mitochondrial genesis during myocardial
cell hypertrophy and hyperplasia (rats)
ROlHL-20859-02 Beta adrenergic catecholamine receptor
ROlHL-20905-02 Synthesis of fetal hemoglobin in erythroid
cells (sheep, human)
R23HL-22490-01 Neurotransmitter receptors of cultured
heart cells
S09
ROIHI 22607 01 Role o( apolipoprotein E in lipoprotein
metabolism (human)
POIHL 22619 01 0010 Cellular mechanisms ol heart
failure Mitochondria in heart and smooth muscle (rabbits,
rats, dogs)
R01HL2287301 Adrenoceptor interconversion and
hormone homeostasis
ROIHL 23736 04 Sickle cell anemia and hemoglobin
synthesis (monkeys)
THYROID HORMONES, DEXTROTHYROXINE
ROIHL 08888 12 Cooperative study of drugs and coronary
heart disease (men)
ROIHL 10445 09 Cooperative study ol drugs and coronary
heart disease (men)
ROIHL 1070509 Cooperative study of drugs and coronary
heart disease (men)
ROIHL 11372 08 Cooperative study ol drugs and coronary
heart disease (men)
THYROID HORMONES, (THYRO)CALCITONIN
ROlHL-22561 01 Hormonal control of mesenteric
circulation (cats)
THYROID HORMONES, THYROXINE
SEE ALSO HALOPROTEINS. THYROXINE BINDING PROTEINS
POIHL 06835 17 0016 Cardiovascular disease Metabolic
interactions to polyunsaturated fatty acids in atherogenic
diet (dogs)
ROIHL 1050313 Cardiac ion transport and ultrastructure
(rats, guinea pigs, rabbits)
P50HL142 18-07 0017 Pulmonary SCOR -Newborn lung
center Transvascular fluid exchange, vasoactive mediators
in ROS (sheep, cat)
•* ROlHL-15316-07 Lung surfactant system -Control
mechanisms (rats)
** ROlHL-1643604 Role of calcium and thyroxine in heart
function (rats)
R01HL17932-04 Blood flow regulation in muscle (cats)
ROIHL 19669-03 Lung organ culture and surfactant
biosynthesis (adult and fetal rats)
ROlHL-19752-03 Phospholipid synthesis by fetal lung in
organ culture (rats)
R23HL22490-01 Neurotransmitter receptors of cultured
heart cells
THYRONINE, TRIIODOTHYRONINE
ROlHL-16364-04 Regulation of lipid biosynthesis and
transport (rats, swine. Xenopus)
ROlHL-18938-03 Pulmonary fatty acid and phospholipid
metabolism (rats)
THYROTOXICOSIS
SEE THYROID GLAND DISORDERS, HYPERTHYROIDISM
THYROTROPIN
SEE PITUITARYDIENCEPHALON HORMONES, THYROTROPIN
THYROXINE
SEE THYROID HORMONES, THYROXINE
THYROXINE BINDING PROTEINS
SEE HALOPROTEINS. THYROXINE BINDING PROTEINS
TIME
SEE ENVIRONMENT, CLIMATE, SEASONS
TIME DEPENDENT COMPUTER DATA
SEE COMPUTER, TIME-DEPENDENT COMPUTER DATA
TIME DOMAIN SPECTROSCOPY
SEE OPTICS. INTERFEROMETRY*
TIME RELEASE DRUGS
SEE DRUGS, SLOW RELEASE PREPARATIONS
TISSUE (GENERAL)
SEE ALSO CONNECTIVE TISSUE (GENERAL)
SEE ALSO HISTOLOGY (GENERAL)*
** POlHL-144 14-07 0014 Environmental influences on
cardiorespiratory and cellular functions - Temperature and
acid-base status in tissues, cells, and subcellular system
POlHL-15194-07 0006 Pathophysiology of
cardiopulmonary dysfunction - Kinetics of gas exchange -
Velocity of Bohr effect in erythrocytes (human)
POlHL-15194-07 0009 Pathophysiology of
cardiopulmonary dysfunction ■ Kinetics of gas exchange-
Diffusion and erythrocytes reaction rates (human, dogs)
ROlHL-17503-03 Vascular bubbles in decompression
sickness (minipig, dog, goat)
** ROlHL-20607-02 Tissue analysis by mass spectrometer
(dogs)
TISSUE, EPITHELIUM
SEE ALSO CARDIOVASCULAR SYSTEM, ENDOTHELIUM
SEE ALSO MEMBRANE
POlHL-06285-18 0193 Cardiovascular-respiratory
physiology and biochemistry - Hormonal regulation of
sodium transport-Aldosterone (rats, toads)
** POlHL-06285-18 0196 Cardiovascular-respiratory
physiology and biochemistry ■ Hormonal regulation of
sodium transport-Epithelial cell membranes (toads)
POlHL-06285-18 0209 Cardiovascular-respiratory
physiology and biochemistry - Metabolic studies of isolated
lung cells (human, animals)
TIS
POIHI 05664 1/ 0038 Cardiopulmonary function in
remediable vascular disease The dynimici ol ADH
stimulated osmotic water flow
•• POIHI 06664 1/ 0039 Cardiopulmonary function in
remediable vascular disease Transepithelial active
transport and cell volume regulation (frogs)
•• POIHL 06664 17 0040 Cardiopulmonary function in
remediable vascular disease The coupling ot ion transport
to metabolism (toads)
ROIHL 12650 08 Environmental pathobiology ot the lung
(hamsters, rats)
M ROIHL 1287909 Pulmonary transport and metabolism in
vivo
•* ROIHL 12879 09 0005 Pulmonary transport and
metabolism in vivo Glucose transport by pulmonary
endothelium and epithelium (dogs)
ROIHL 12879 09 0007 Pulmonary transport and
metabolism in vivo Effects of temperature changes on
pulmonary transport
ROIHL 12879 09 0008 Pulmonary transport and
metabolism in vivo Stop flow technique for permeability
measurements
*• ROIHL 12879 09 0011 Pulmonary transport and
metabolism in vivo Membrane characteristics ol lung
cells (human, animals)
ROIHL 12974 10 Tracer kinetics, flows and masses in
body organs (human, dogs)
ROIHL 13885 08 0009 Cystic fibrosis and pulmonary
disease Respiratory mucus glycoproteins (human, rabbits)
POIHL 1438807 0179 Regulation ol the circulation in
pathological states Cultured muscle cells and their cross
innervation in vitro (rats, sheep)
•• POIHL- 14388-07 0191 Regulation of the circulation in
pathological states Regulation of chloride transport in
epithelial membranes (turtles)
** R01HL14844-06 Mucous glycoprotein in human respiratory
epithelium (also wheat)
P01HL15832-06 0012 Chemical structural predispositions
to lung injury Contractile structures and contractility in
cells of lung respiratory tract
** R01HL16674-05 Airborne metals and lung permeability
(bullfrogs, rats)
ROlHL-1673003 Physiology of mucociliary transport (rats,
frogs, rabbits)
R01HL17571-03 Study of membrane permeability by NMR
relaxation (human)
P50HL-1915602 0001 Pulmonary SCOR-Chronic diseases
of ainways ■ Irritability of airways induced by epithelial
damage in healthy subjects (human)
P50HL19155-02 0005 Pulmonary SCOR-Chronic diseases
of airways - Vagal receptors in the airway-Epithelial injury
and antigen (dog. cat, rabbit)
P50HL-1917102 0009 Pulmonary SCOR-Lung injury by
childhood infections ■ Host-parasite interaction-Scanning
electron microscopy, freeze-fracture methods
P50HL19171-02 0010 Pulmonary SCOR-Lung injury by
childhood infections • Metabolic pathways of normal and
injured respiratory cells
P50HL19185-02 0005 Pulmonary SCOR-Neonatal
respiratory distress syndromes - Role and mechanism of
glucocorticoids in fetal lung maturation (human, rabbit)
P50HL19190-02 0003 Pulmonary SCOR -Pathophysiology,
management of IRDS - Type II cells-Regulation and
differentiation (rat)
P50HL1919002 0004 Pulmonary SCOR-Pathophysiology,
management of IROS ■ Type II cells-Control of protein
turnover (rabbit)
POlHL-19717-02 0014 Response of the lung to injury •
Stereology of epithelialized bronchi in evolving elastase
emphysema (hamsters)
ROlHL-20878-02 Cellular aspects of lung injury (rats,
rabbits)
ROlHL-21076-02 Lung fluid, protein exchange after
hemorrhagic shock (sheep)
R23HL-21150-02 Regulation of airway mucous glands and
ion transport (dogs, ascaris)
ROlHL-21314-02 Respiratory tract secretion of ions, water
and mucus (human, dogs)
ROlHL-21376-02 Blood-gas barrier solute and water
transport (rabbits)
** R23HL-21396-02 Isolation, growth and metabolism of type
1 pneumocytes (rabbits)
** ROlHL-21849-02 Control of sodium transport and cellular
respiration (toad bladder)
ROlHL-22552-02 Abnormal alveolar permeability and lung
disease (sheep)
** ROlHL-22883-01 Lung epithelial cell interactions in vitro
** ROlHL-22924-01 The airway mucosal barrier (guinea pigs)
ROlHL-23981-01 Acute alveolar injury (dogs)
TISSUE, ORGANS (SEE ALSO SPECIFIC ORGANS)
P01HL08899-14 0042 Tolerance to respiratory gases in
health and disease • Definitions and extension of oxygen
tolerance in organ systems (animals)
** POlHL-08899-14 0055 Tolerance to respiratory gases in
health and disease ■ Oxygen effects on organ functions-
Extension of tolerance
ROlHL-22406-01 Isobaric vascular bubbles and
decompression sickness (goats, models)
TISSUE AND CELL PREPARATION
SEE ALSO TEMPERATURE. FREEZE-ETCHING*
•Excludes routine methodology OR covers only general projects which preclude i
••Oriented significantly to above subject.
ndexing at the specific level.
M Grant has subprojects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
'.'VtfAXnnW^cjvJCFjd
TIS
** ROlHL-01770-26 Structural aspects of lung surfactant
system (rats)
R01HL16730-03 Physiology of mucociliary transport (rats.
frogs, rabbits)
P50HL1 7648-04 0013 Study of ischemic heart disease -
Fate of bypassed and bypassing vessels (dogs)
P50HL-1 7648-04 0020 Study of ischemic heart disease -
Core pathology laboratory-lschemic heart disease (human.
animal)
POlHL-17731-04 0011 Physiological basis of pulmonary
disease - Morphometric studies of the lung-Core
POlHL-20592-02 0013 Cell biology of cardiac and
skeletal muscle ■ Sarcoplasmic reticulum in skinned
muscle cells (frogs)
TISSUE AND CELL PREPARATION, SECTIONING
POlHL-12373-10 0016 Cardiopulmonary physiology and
pathophysiology - Histology-histochemistry-Gough laboratory
TISSUE BANKS
SEE TISSUE RESOURCES, REGISTRIES
TISSUE (CELL) CULTURE*
POlHL-03 174-23 0005 Mechanisms of acute vascular
reaction to injury - Renal small vessel didease-Cel! and
matrix response (human, mice)
POlHL-06285-18 0209 Cardiovascular-respiratoiy
physiology and biochemistry - Metabolic studies of isolated
lung cells (human, animals)
POIHL-06314-17 0048 Immunologic mechanisms in
cardiovascular disease - Pathogenesis of glomerulonephritis
(rats, mice)
POlHL-0631417 0054
cardiovascular disease
Immunologic mechanisms in
Physiology of cell communications
(mice, frogs, guinea pigs)
POlHL-06314-17 0055 Immunologic mechanisms in
Genetics and cell biology
Immunologic mechanisms in
Glomerular cells in tissue culture
cardiovascular disease
• POlHL-06314-17 0063
cardiovascular disease
(human)
POlHL-07896-15 0047 Environmental biomedical research
program - Pulmonary oxygen toxicity (chickens, rabbits)
' POlHL-08214-15 0023 Chemical and biological properties
of lipids - Lipids in microorganisms and cell cultures
(hamsters, mosquitoes)
POlHL-08214-15 0030 Chemical and biological properties
of lipids - Fatty acid biosynthesis in plant cell cultures and
in plants
R01HI.-10018-11 Effect of aging on beating heart cells in
culture (rats)
POIHLI 1351-12 0011 Cellular and molecular
mechanisms of myocardial function - Comparative
contractile tissue studies (animals)
• POlHL-11351-12 0020 Cellular and molecular
mechanisms of myocardial function - Electrophysiology of
cultured heart cells
• POlHL-12157-11 0055 Functions and mechanisms of cell
membrane ion transport ■ Growth and development of
synthetic strand heart cells in culture (chick embryo)
• POlHL-12738-10 0135 Physiologic pharmacology and its
clinical applications - Myocardial cells in tissue culture
(rats, chick embryo)
ROlHL-12766-09 Structure-function relation of blood
vessels (rats, monkeys)
ROlHL-12879-09 0011 Pulmonary transport and
metabolism in vivo - Membrane characteristics of lung
cells (human, animals)
POlHL-13108-09 0010 Clinical heart transplantation -
Serum factors inhibiting lymphocyte responses in MLC
(human, bush babies)
P0IHL13108-09 0015 Clinical heart transplantation -
Antithymocyte globulin analysis and clinical effects
POIHL-13262-07 0012 Arterial wall in atherosclerosis -
Characterization of connective tissue components (animals)
POlHL-13330-08 0056 Mechanical circulatory support -
Blood compatibility linings (calves)
P50HL-14138-05 0015 Center for research on
atherosclerosis ■ Arterial wall-Intermediary metabolism,
enzyme activity and bioenergetics
P50HL-14147-08 0012 Specialized center of research in
thrombosis - Tissue culture study of arterial cells (human,
hamster)
P50HL 14218-07 0006 Pulmonary SCOR-Newborn lung
center - Biochemical characteristics of the lung in ROS
(human, sheep)
P50HL-14230-07 9002 A/S SCOR -Lipids, atherosclerosis
and thrombosis - Core tissue culture laboratory
POIHL-14388-07 0179 Regulation of the circulation in
pathological states - Cultured muscle cells and their cross-
innervation in vitro (rats, sheep)
ROlHL-14717-06 Hemodynamics and heart structure-
Ventricular overload (dogs)
P50HL-15062-07 0020 Study of lipoproteins, artery wall,
and atherosclerosis - Artery wall reactions-Elevated
pressure and hyperlipemia (monkey)
ROlHL-15316-07 Lung surfactant system -Control
mechanisms (rats)
ROlHL-15685-05 Hemopoietic regulators produced in cell
culture (human, animals)
ROlHL-15740-06 In vitro studies on heart cell function
(rats)
510
POlHL-15832-06 0004 Chemical-structural predispositions
to lung injury - Proteolytic activity leucocytes in patients
with obstructive lung disease
■ POlHL-15832-06 9001 Chemical-structural predispositions
to lung injury - Tissue culture studies of lung cell function-
Core facility
POlHL-161 17-05 0001 Ion movements and membranes in
cardiovascular control - Developmental studies of
contractile cell junctions (rats, rabbits, elasmobranch)
POlHL-16137-05 0004 Alveolar biology - Subcellular
processes and controls in the surfactant system (animals)
POlHL-16387-04 0004 The blood vessel and
thrombogenesis - Analysis of vascular basement membrane
by enzymatic methods (human)
ROlHL-167 14-05 Endothelial cell communication in
homeostasis (human, mammals)
R01HL-16725-03 Physiological regulation of pulmonary
surfactant (dogs, rats)
P01HL-16769-05 0004 Pathobiologic and host defense
reactions in the lung - Pathogenesis of Pseudomonas and
Serratia pneumonias (rabbits)
' POlHL-16769-05 0009 Pathobiologic and host defense
reactions in the lung - Electron microscopy and tissue
culture core laboratory
POlHL-16833-04 0009 Hemoglobin and red cell system in
hemoglobinopathies - Rheological studies of sickled cells
(human)
ROlHL-16918-05 Role of steroids in hypertension (human)
P60HL-1 7269-04 0035 National heart and blood vessel
research and demonstration center - Blood resources -
Research program in viral hepatitis (human)
POlHL-17419-04 0006 Studies on mechanisms of
hemostasis - Effect of hormones, drugs and other agents
on fibrinogen synthesis (chick)
' POlHL-l 7430-05 0008 Control of coagulation - Cultures
of von Willebrand endothelial cells (pigs)
P50HL- 17648-04 0025 Study of ischemic heart disease -
Destruction and repair of cardiac muscle cell constituents
(rat)
P50HL-17648-04 0028 Study of ischemic heart disease -
Electrophysiology of sympathetic innervation in tissue
culture
P50HL-17682-04 0018 Study of ischemic heart disease -
Biochemistry of ischemia-Heart cell and organ culture
(mice. rats, cattle)
P50HL-17682-04 0023 Study of ischemic heart disease -
Core cell and organ culture laboratory (mice)
POlHL-17813-04 0008 Lung disease and the oxygenation
of blood and tissue - Pulmonary regulation of systemic
blood pressure (human, rabbits, rats)
ROlHL-17973-04 Cultured aortic endothelial cells (human.
cattle, dogs, swine)
POlHL-18645-03 Biology of the artery wall and
atherosclerosis
POlHL-18645-03 0001 Biology of the artery wall and
atherosclerosis - Primate arterial smooth muscle and
atherosclerosis
POlHL-18645-03 0003 Biology of the artery wall and
atherosclerosis - Synthesis of connective tissue proteins by
smooth muscle cells (human, monkeys)
POlHL-18645-03 0004 Biology of the artery wall and
atherosclerosis - Human arterial smooth muscle cell and
lipoprotein interaction
POlHL-18645-03 0005 Biology of the artery wall and
atherosclerosis - Effects of atherosclerosis risk factors on
endothelium of the primate
ROlHL-18647-03 Ischemic myocardial injury in cultured
heart cells (rats)
P01HL-18708-03 0007 Oxygen, energy and contractility in
cardiac tissue - Surfaces, energy requirements, and
contractile proteins of cardiac cell in vitro
POlHL-18708-03 0008 Oxygen, energy and contractility in
cardiac tissue - Cardiac cell culture facility
ROlHL-187 11-03 Electrophysiology of heart cells (rats.
chicks)
POlHL-18827-02 0001 Platelet vessel wall interactions in
thrombogenesis - Role of endothelial cells in the production
of thrombi (human, cattle)
P50HL-19190-02 0003 Pulmonary SCOR-Pathophysiology,
management of IRDS - Type II cells-Regulation and
differentiation (rat)
P50HL-191 90-02 0004
management of IRDS
turnover (rabbit)
ROlHL-19229-02 Prostaglandins and hypertension (human.
rats, dogs, rabbits)
ROlHL-19287-03 The antihypertensive function of the
renal medulla (human, rats, rabbits)
ROlHL-19684-03 Histotypic lung culture in circumfusion
systems (mice)
ROlHL-19685-03 Pathogenesis of inflammation of the lung
(guinea pigs)
POlHL-19717-02 0002 Response of the lung to injury -
Prolyl hydroxylase, lysyl hydroxylase and lung collagen
biosynthesis (rabbits)
POlHL-197 17-02 0007 Response of the lung to injury -
Cellular level studies of prostaglandin-like molecules
(cattle)
POlHL-19737-02 0013 Cellular and molecular aspects of
respiratory physiology - Cell metabolism analytical facility
ROlHL-20054-02 Cultured blood vessel cells-
Pathophysiology (human, animals)
TIS
Hypertension and vascular steroid
Analysis of heart cell contraction (rats)
Atherosclerosis and arterial cell functions
Pulmonary SCOR-Pathophysiology.
Type II cells-Control of protein
R01HL-2020I-01
receptors (rats)
ROlHL-2064302
ROlHL-20924-02
(human, rabbits)
POlHL-20948-02 0001 Molecular basis of cholesterol
metabolism - Biochemical and ultrastructural
characterization of LDL in human fibroblasts
POlHL-20948-02 0002 Molecular basis of cholesterol
metabolism - LDL pathway in cell lines with informative
properties other than fibroblasts
POlHL-20948-02 0003 Molecular basis of cholesterol
metabolism - LDL pathway in vivo (human, rats, guinea
pigs)
POlHL-20948-02 0004 Molecular basis of cholesterol
metabolism - Genetic analysis of the LDL pathway (human)
POlHL-20948-02 9001 Molecular basis of cholesterol
metabolism - Tissue culture core laboratory
POlHL-20993-02 0007 Population dynamics of arterial
cells in atherogenesis - Interaction of lipoproteins in
hypercholesteremia (human, swine)
ROlHL-2 1038-01 Electrically induced cardiac EM-
histochemical changes (animals)
ROlHL-21751-02 0001 Thallium and antimyosin in
ischemia and infarction - In vitro models of ischemia and
infarction (rats, mice)
R23HL-21950-01 Endothelial cell mechanisms in vascular
disease (human)
ROlHL-22077-01 Vasoactive amine disposition in cultured
endothelium (rabbits)
ROlHL-22137-02 Structure-function pathology of isolated
heart cells (mice, rats)
ROlHL-22444-01
culture (human)
ROlHL-22486-01
Bronchial mucus production In organ
Enzyme regulation in cultured arterial
•Excludes routine methodology OR covers only general projects which preclude indexing
••Oriented significantly to above subject.
at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
cells (swine)
ROlHL-22527-01 Prostacyclin-thromboxanes in the
cardiovascular system (human, rabbits)
M POlHL-22602-01 Pathophysiology of the endothelium
** POlHL-22602-01 0001 Pathophysiology of the
endothelium - Platelet-endothelial interactions in vitro
(human, cattle)
POlHL-22602-01 0002 Pathophysiology of the
endothelium - Molecular charge and endothelial
permeability (rats, mice)
** POlHL-22602-01 0003 Pathophysiology of the
endothelium - Mechanisms of endothelial proliferation
(human, animals)
** POlHL-22602-01 9002 Pathophysiology of the
endothelium - Core -Culture of blood vessel-Derived cells
ROlHL-22623-01 Polyamines cellular mediators of
atherogenesis (human)
*• POlHL-22633-01 0002 Cellular and molecular biology of
lipoprotein metabolism - Sterol metabolism in tissue
culture cells
** POlHL-22633-01 9001 Cellular and molecular biology of
lipoprotein metabolism - Tissue culture core
ROlHL-22924-01 The airway mucosal barrier (guinea pigs)
ROlHL-22939-01 Human kinin and fibrinolytic systems
and renal disease (human)
** ROlHL-23542-01 Pulmonary vascular smooth muscle cell
dynamics (rat. rabbit)
** N01HV-12060-18 Tissue cultured endothelium for vascular
prosthetic devices (human, animals)
NOlHV-81388-20 Microfiber substrate for growth of intimal
linings in circulatory assist devices
TISSUE (CELL) CULTURE, CELL CULTURE
COLLECTIONS BANKS AND REGISTRIES
SEE ALSO TISSUE (CELL) CULTURE, EMBRYONIC-FETAL CELL
LINES
POlHL-19737-02 0003 Cellular and molecular aspects of
respiratory physiology - Cortisol-dependent alterations in
lung type II cells (rats)
** NOlHR-62930-03 Lung cell resource facility
TISSUE (CELL) CULTURE, CLONE CELLS*
SEE ALSO NEOPLASTIC CELLS, HELA CELLS
POlHL-03174-23 0010 Mechanisms of acute vascular
reaction to injury - Search for mutagens in the human
blood (bacteria, animals)
POlHL-15835-06 0009 Study of muscles related to heart
disease - Aspects of cardiac and skeletal myogenesis
(chick embryo)
POlHL-15835-06 0025 Study of muscles related to heart
disease - Cellular biology of vascular smooth muscle
(guinea pig)
POlHL-16137-05 0008 Alveolar biology - Macromolecular
events in pulmonary cells in toxic environments (animals)
ROlHL-18473-04 Genesis of atherosclerotic lesions
(human, mules)
P50HL-19171-02 0010 Pulmonary SCOR-Lung injury by
childhood infections - Metabolic pathways of normal and
injured respiratory cells
** POlHL-19259-03 0001 Digoxin-specific antibody in human
therapy - Primary structure of monoclonal antibodies
(rabbits)
** POlHL-19259-03 0003 Digoxin-specific antibody in human
therapy - Synthesis of dogoxin-specific antibody in
continuous cell culture (human, sheep)
ROlHL-20913-02 Cell culture studies of
hemoglobinopathies (human)
(contd)
tis
•• POIHL 20993 02 0003 Populition dynamics of •rt«rl»l
cells in »th«fOienesis Clonal phenomena in athetogenesis
(human, hares)
POIHI 20993 02 0009 Population dynamics o1 arterial
cells in atherotenesis Mathematical biology Core
•• POIHI 21016 02 0012 SicKle cell anemia and other
hemotlobinopathies Stimulation ol Hb F synthesis in a
permanent cell line
POIHL 22633 01 9001 Cellular and molecular biology ol
lipoprotein metabolism Tissue culture core
ROIHL 23969 01 Surlactant synthesis by type II cells in
vitro (rats)
TISSUE (CELl) CULTURE, EMBRYONIC-FETAl CELL
UNES
ROIHL 22266 01 Production ol proteases by lung cells in
culture (human, rodents, rabbits, sheep)
TISSUE (CEIL) CULTURE, MIXED CULTURES
SEE ALSO TISSUE COMPATIBILITY TRANSPUNT.
HISTOCOMPATIBILITY TYPING, MLC
PO1HL06314-17 0050 Immunologic mechanisms in
cardiovascular disease - Physiologic changes in
lymphocytes (human, mice)
P01HL06314 17 0054 Immunologic mechanisms in
cardiovascular disease Physiology ol cell communications
(mice, frogs, guinea pigs)
P01HL0631417 0059 Immunologic mechanisms in
cardiovascular disease Immunogenetic response to
streptococcal antigens in man
P01HL06314-17 0066 Immunologic mechanisms in
cardiovascular disease Sensitization, cell-mediated
cytotoxicity, role of lymphocytes (human, mice)
POIHL- 13 10809 0013 Clinical heart transplantation -
Cardiomyopathic lymphocyte responsiveness to cultured
endothelium
** P50HL14212-07 0016 Correlated studies of pulmonary
fibrosis - Role of pulmonary alveolar macrophages in
fibrosis (human, rabbit)
POlHL-15832-06 0002 Chemical-structural predispositions
to lung injury - Connective tissue in lung in development
and repair of injury (human, rats, mice)
P50HL-17648-04 0028 Study of ischemic heart disease -
Electrophysiology of sympathetic innervation in tissue
culture
POlHL-1864603 0003 Studies basic to heart
transplantation - Host responses to xenografts (rodents,
rabbits)
TISSUE (CELl) CULTURE, ORGAN CULTURE
** POlHL-03174-23 0012 Mechanisms of acute vascular
reaction to injury - Human atherosclerotic plaque in organ
culture
** POlHL-06285-18 0152 Cardiovascular-respiratory
physiology and biochemistry - Diabetic microangiopathy by
organ and tissue culture (human)
*♦ ROlHL-14706-07 Fetal hearts in organ culture (mice)
** P50HL-17648-04 0026 Study of ischemic heart disease -
Control of muscle cell proliferation (organ culture)
** P50HL-17682-04 0018 Study of ischemic heart disease -
Biochemistry of ischemia-Heart cell and organ culture
(mice, rats, cattle)
•• P50HL-17682-04 0023 Study of ischemic heart disease -
Core cell and organ culture laboratory (mice)
R01HL-187I1-03 Electrophysiology of heart cells (rats.
chicks)
POlHL-19242-02 0003 Study of vascular smooth muscle -
Vasoactive metabolites from vascular muscle and
parenchymal tissue (animal)
ROlHL-19668-03 Biochemistry of lung connective tissue
(rats)
POlHL-19717-02 0001 Response of the lung to injury -
Lung elastic tissue (animals)
ROlHL-19752-03 Phospholipid synthesis by fetal lung in
organ culture (rats)
** POlHL-20984-02 9002 Cellular mechanisms in cardiac
hypertrophy - The heart in organ culture
ROlHL-22040-01 Regulation of lysylcross-linking in
vascular tissue (rats, turkeys)
R23HL-22959-01 Heart development in inherited
cardiomyopathy (hamsters)
TISSUE COMPATIBILITY
SEE TISSUE COMPATIBILITY-TRANSPLANT. ISOALLOIMMUNITY
TISSUE COMPATIBILITY-TRANSPLANT,
HISTOCOMPATIBILITY TYPING
SEE ALSO BLOOD GROUPS
SEE ALSO BLOOD PLATELET TYPING
POlHL-06314-17 0066 Immunologic mechanisms in
cardiovascular disease • Sensitization, cell-mediated
cytotoxicity, role of lymphocytes (human, mice)
M POlHL-06370-17 Cardiopulmonary and renal pathology
research center
** POlHL-06370-17 0004 Cardiopulmonary and renal
pathology research center - Lymphocytes in graft rejection
and immune surveillance (human)
P01HL09011-15 0001 A research and resource program
in blood • Genetic markers of human blood and gene
mapping (human)
ROlHL-1398704 Transplantation of the lung (dogs)
** ROlHL-161 19-05 Spleen and marrow allografts in
hereditary anemia (mice)
511
POlHt 18646 03 0004 Studies basic to heart
transplantation Presensiti/alion Detection, incidence and
clinical significance
TISbUE COMPATIBILITY-TRANSPLANT,
HISTOCOMPATIBILITY TYPING, LEUKOCYTE
TYPING
NOIHB 629/0 02 Collection, function and transfusion of
granulocytes
NOlHB-62973 05 Collection, function and transfusion of
granulocytes
POIHL 06314 17 0059 Immunologic mechanisms in
cardiovascular disease Immunogenetic response to
streptococcal antigens in man
POIHL 13108-09 0001 Clinical heart transplantation •
Therapy and prognosis (human)
P60HL 17265 04 0006 Community blood resource center
support Research Evaluation of platelet transfusions
(human, dog)
P60HL 17265 04 0009 Community blood resource center
support Research Developing granulocyte transfusion
therapy (human, rabbit)
ROIHL 19984 02 Blood pressure and immunogenetic
factors in the young (human)
NOlHR-62935-02 Histocompatibility antigens -Evolution ol
respiratory hypersensitivity (human)
TISSUE COMPATIBILITY -TRANSPLANT,
HISTOCOMPATIBILITY TYPING, MLC
ROlHL-08696-15 0011 Orthotopic heart transplantation -
Transplantation immunology-lmmunodepressive factor
(human, dogs)
ROlHL-08696-15 0014 Orthotopic heart transplantation -
Transplantation immunology -Cardiac retransplantation
(dogs)
** POlHL-13108-09 0010 Clinical heart transplantation -
Serum factors inhibiting lymphocyte responses in MLC
(human, bush babies)
ROlHL-23631-01 Immunogenetic factors in allergic
respiratory diseases (human)
TISSUE COMPATIBILITY-TRANSPLANT, IMPLANT
SEE ALSO PROSTHESIS
** ROlHL-01803-23 0010 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Atherosclerosis induction -Graft rejection
and hypercholesterolemia (rabbits)
POlHL-06312-17 0030 Surgical cardiology - Total
artificial heart (calves)
POlHL-06370-17 0013 Cardiopulmonary and renal
pathology research center - Morphologic analysis of
vascular prosthesis (human, dogs)
POlHL-13737-07 0002 Assisted circulation - U-shaped
mechanical auxiliary ventricle (dogs)
P01HL13737-07 0032 Assisted circulation - The dynamic
aortic patch (human, dogs)
ROlHL-13988-07 Elimination of reoperative cardiac
pacemaker surgery (dogs)
R01HL-15247-05 Extending the life of implanted
pacemakers (dogs, human)
M ROlHL-17993-04 Ventricular dynamics from surgically
inserted markers
** ROlHL-17993-04 0002 Ventricular dynamics from
surgically inserted markers - Lett ventricle function in
human cardiac allograft
ROlHL-18639-03 Human anatomy for cardiac prostheses
(human)
** R01HL19173-03 Analysis of blood trauma from
microporous oxygenators (human, dogs, rabbits)
** ROlHL-194 19-03 Cellular interactions with foreign
materials (mammals)
R01HL-19425-03 Cardiac function in hypertrophy (dog)
ROlHL-19898-03 Desferrioxamine therapy in thalassemia
(dogs. rats, children)
ROlHL-21001-01 Protein and thrombus deposition on
vascular grafts
ROlHL-21674-01 Development of automatic implanted
defibrillator (dogs, cattle)
ROlHL-221 10-02 Healing complications in vascular
grafting (dogs)
ROlHL-22585-01 Plasma proteins adsorbed to artificial
organs (human, rabbits)
ROlHL-23899-01 Flow and flexing at blood/biomaterial
interfaces
NOlHV-12065-16 Fabrication of implantable artificial heart
devices (animals)
** NOlHV-42969-06 Interactions of natural and chemically
modified biopolymers with blood (dogs)
** NOlHV-53006-06 Evaluation of model VII left ventricular
assist device (human)
NOlHV-629 11-04 Vena cava ring tests of biomaterials in
dogs
NOlHV-72934-01 Development of a left heart assist blood
pumps (human, cattle)
TISSUE COMPATIBILITY-TRANSPLANT, IMPLANT
COMPATIBILITY
POlHL-1 14 14-11 0027 Thrombosis and atherosclerosis
program - Thermal memory wire filter to prevent pulmonary
embolism (human, dogs)
ROlHL-1 14 18-09 Poly-diaminophosphazenes
ROlHL-1 1945-10 Synthesis of artificial lung and kidney
systems (sheep, mice, swine)
TIS
POIHL 13330 08 0034 Mechanical circulatory support In
VIVO test and evaluation of left venlriculaf byp»ii pump*
(human, cattle)
•• POIHI 13330 08 0056 Mechanical circulatory tuppoil
Blood compatibility linings (calves)
ROIHL 13426 09 Left ventricular bypass for myocardial
infarction (cattle, human)
POIHL I373;0/ 0029 Ajsisled circulation Chronic left
ventricular failure (human)
ROIHL 13803 07 Advanced cardiac valvular and vaiculir
prosthesis (dogs, baboons)
M POIHL 15195 04 Program proiect in biological material'
POIHL 1519504 0001 Program project in biological
materials Design and synthesis
POIHL 1519504 0002 Program project m biological
materials Structural and surface characterization
POIHL 15195 04 0003 Program proiect in biological
materials Mechanical evaluation and fabrication
** POIHL 1519504 0004 Program protect in biological
materials Biological evaluation and surface interaction
studies (dogs)
ROIHL 15668-06 Extracorporeal respiratory gas exchange
A new approach (dogs)
** ROIHL 1692105 Synthetic hydrogels as blood tolerable
materials
ROlHL-17623-05 Initial events in thrombus formation on
surfaces (human, rats)
ROlHL-17973-04 Cultured aortic endothelial cells (human,
cattle, dogs, swinc)
ROlHL-18084-03 Artificial heart and related problems
(calves)
*• POIHL 18576-03 0003 Thrombosis research program
project Biocompatible materials
ROlHL-18644-03 Prosthesis for aortocoronary bypass
(dogs, baboons)
** ROlHL-19055-03 Platelet function during extracorporeal
perfusion (human, mammals)
** ROlHL-20073-02 Blood compatible materials by fluid
perfusion (human, dogs)
** ROlHL-20079-02 0003 Thromboresistant material - Blood
surface interactions (human, cattle)
ROlHL-20251-02 A novel approach to nonthrombogenic
polymer surfaces (sheep, cattle)
** ROlHL-20313-02 Surface-induced thrombosis -Modification
of albumin variants (human, goat)
ROlHL-20356-02 Development and evaluation of an
artificial heart (calves)
** R23HL-21805-01 Tissue cell interactions with vascular
prostheses (human, rats, mice)
** ROlHL-2389901 Flow and flexing at blood/biomaterial
interfaces
NOlHV-12017-15 Fabrication of grafted hydrogel coatings
for plastic heart assist devices
NOlHV-12054-14 Development of intimal linings (human,
cattle)
•* NOlHV-12060-18 Tissue cultured endothelium for vascular
prosthetic devices (human, animals)
NOlHV-32913-11 Study electrodeless glow discharge for
modifying polymer surface
N01HV-32917-08 Materials development and testing
** NOlHV-32919-12 Material development and testing
heparinization processes
•* N01HV-32950-08 Blood compatible poly-electrolytes
** NOlHV-32953-10 Materials compatible with blood (dogs)
** NOlHV-32959-10 Development of materials for heart assist
devices
** NOlHV-42914-13 Solenoid left ventricular assist system
(cattle)
NOlHV-42960-07 Development and evaluation of cardiac
prostheses (calves)
NOlHV-42961-06 Evaluation of biomaterials in contact
with blood (dogs)
NOlHV-72933-01 Electrical energy transmission technique
development (dogs)
NOlHV-81388-20 Microfiber substrate for growth of intimal
linings in circulatory assist devices
TISSUE COMPATIBILITY-TRANSPLANT,
ISOALLOANTIBODIES
SEE ALSO BLOOD GROUPS ISOANTIBODIES
SEE ALSO IMMUNITY, IMMUNOSUPPRESSION, ALLOANTISERA
** ROlHL-08696-15 0011 Orthotopic heart transplantation -
Transplantation immunology-lmmunodepressive factor
(human, dogs)
ROlHL-20140-02 Glycoproteins of platelet membrane and
platelet function (human)
ROlHL-20856-02 Platelet transfusions -Usage and
complications (human)
" ROlHL-23654-01 Selected topics on blood transfusion
(rabbits, human)
TISSUE COMPATIBILITY-TRANSPLANT,
ISOALLOANTIGENS
SEE ALSO BLOOD GROUPS ANTIGENS
** ROlHL-01623-24 Antigens related to graft rejection
(rabbits, rats)
ROlHL-03919-20 The cell suface of streptococci (rats,
human)
ROlHL-08696-15 0001 Orthotopic heart transplantation -
Transplantation immunology -Antithymocyte globulin
(rabbits, monkeys)
(contd)
•Excludes routine methodology OR covers only general projects which preclude
"Oriented significantly to above subject.
indexing at the specific level
M Grant has subproiects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
. '^4Am^rjat^tmMJVuL»
TIS
ROlHL-08696-15 0012 Orthotopic heart transplantation -
Transplantation immunology-Modulation of donor
antigenicity (dogs)
RClHL-08696-15 0014 Orthotopic heart transplantation -
Transplantation immunology-Cardiac retransplantation
(dogs)
P01HL-0901M5 0001 A research and resource program
in blood - Genetic markers of human blood and gene
mapping (human)
POlHL-0901115 0012 A research and resource program
in blood ■ Theoretical population genetics (human)
*♦ P01HL1131012 0097 Mechanisms of cardiovascular
disease - Structural-functional relationships of neuronal
differential alloantigens (mice)
** P01HL-1I310-12 0098 Mechanisms of cardiovascular
disease ■ Protein chemistry of thy-1 and related
synaptosomal proteins (mice)
P01HL13 108-09 0003 Clinical heart transplantation -
Endomyocardial biopsy pathology
** POlHL-13 108-09 0012 Clinical heart transplantation -
Human T cell sheep erythrocyte receptors
P01HL13108-09 0015 Clinical heart transplantation -
Antithymocyte globulin analysis and clinical effects
ROlHL-13629-08 Hemorrhagic diseases (human)
ROlHL-iei 19-05 Spleen and marrow allografts in
hereditary anemia (mice)
P60HL-17269-04 0033 National heart and blood vessel
research and demonstration center - Autoallergic response
in cardiomyopathy, atherosclerosis, rheumatic heart disease
P60HL-17269-04 0034 National heart and blood vessel
research and demonstration center - Immunologic
enhancement of cardiac allografts (mice)
POlHL-17417-05 0001 Experimental lung transplantation
- Mechanisms and mediators of lung allograft rejection
(dogs, mice)
ROlHL-18526-03 Kinins and the hur.iar: lung
M P01HL18646-03 Studies basic to heart transplantation
POlHL-18646-03 0001 Studies basic to heart
transplantation - Individualized regulation of
immunosuppression (dogs, rats)
POlHL-1864603 0002 Studies basic to heart
transplantation - Detection of rejection (dogs)
** P01HL18646-03 0004 Studies basic to heart
transplantation - Presensitization-Detection, incidence and
clinical significance
** P01HL1864603 0006 Studies basic to heart
transplantation - Reduction or elimination of existing
presensitizalion (human, animals)
P01HL18646-03 0010 Studies basic to heart
transplantation - Development and study of a heart
preservation chamber (dogs, sheep)
ROlHL-20140-02 Glycoproteins of platelet membrane and
platelet function (human)
ROlHL-21829-01 Etiology of obstructive airway disease in
children (also monkeys)
R23HL-22448-01 Modulation of heart graft antigenicity by
perfusion (rats)
TISSUE COMPATIBILITY-TRANSPLANT,
ISOALLOANTIGENS, LEUKOCYTE
** P01HL13108-09 0002 Clinical heart transplantation ■
Preoperative immunologic studies of cardiac recipients
R01HL14799-07 Cardiac heterotransplantation -
Immunologic modification (mice, rat)
POlHL-1676905 0007 Pathobiologic and host defense
reactions in the lung - Immunogenetic factors in
sarcoidosis (human)
POlHL-18646-03 0004 Studies basic to heart
transplantation - Presensitization-Detection, incidence and
clinical significance
ROlHL-22456-01 Lipoproteins in bioregulation of the
immune response (mice, human)
R01HL-2363I01 Immunogenetic factors in allergic
respiratory diseases (human)
** NOlHR-62935-02 Histocompatibility antigens-Evolution of
respiratory hypersensitivity (human)
TISSUE COMPATIBILITY-TRANSPLANT,
ISOALLOIMMUNITY
SEE ALSO BLOOD GROUP INCOMPATIBILITY
SEE ALSO TISSUE COMPATIBILITY-TRANSPLANT,
HISTOCOMPATIBILITY TYPING
NOlHB-62963-03 International bone marrow transplant
registry
NOIHB-62964-03
registry
•* ROlHL-01623-24
(rabbits, rats)
P01HL0631217 0017
transplantation (human)
POlHL-06312-17 0021 Surgical cardiology ■ Cardiac
transplantation-Effect of immunosuppression on
atherogenesis (monkeys)
POlHL-06312-17 0022 Surgical cardiology - Cardiac
transplant-Experimental simultaneous heart and kidney
transplant (dogs)
P01HL06312-17 0028 Surgical cardiology
in the transplanted denervated heart (dogs)
POlHL-06312-17 0029 Surgical cardiology
lymphatics in the transplanted heart (dogs)
** POlHL-06312-17 0039 Surgical cardiology • Cardiac
transplantation Biopsy correlates of rejection
International bone marrow transplant
Antigens related to graft rejection
Surgical cardiology ■ Cardiac
Coronary flow
Cardiac
512
POlHL-06314'17 0066 Immunologic mechanisms in
cardiovascular disease - Sensitization, cell-mediated
cytotoxicity, role of lymphocytes (human, mice)
POlHL-06370-17 Cardiopulmonary and renal pathology
research center
POlHL-06370-17 0001 Cardiopulmonary and renal
pathology research center - The humoral and cellular
mechanisms of allograft rejection (monkeys)
POlHL-06370-17 0004 Cardiopulmonary and renal
pathology research center Lymphocytes in graft rejection
and immune surveillance (human)
POlHL-06370-17 0013 Cardiopulmonary and renal
pathology research center - Morphologic analysis of
vascular prosthesis (human, dogs)
ROlHL-08696-15 Orthotopic heart transplantation
ROlHL-08696-15 0001 Orthotopic heart transplantation -
Transplantation immunology-Antithymocyte globulin
(rabbits, monkeys)
R01HL-08696-1S 0004 Orthotopic heart transplantation -
Transplantation immunology-Avian antibody studies
(chickens, rats, rabbits)
R01HL0869615 0010 Orthotopic heart transplantation -
Transplantation immunology-Total lymphoid irradiation
(dogs, primates)
ROlHL-08696-15 0011 Orthotopic heart transplantation •
Transplantation immunology-lmmunodepressive factor
(human, dogs)
ROlHL-08696-15 0012 Orthotopic heart transplantation -
Transplantation immunology-Modulation of donor
antigenicity (dogs)
ROlHL-08696-15 0013 Orthotopic heart transplantation -
Transplantation immunology-Cardiac heterotransplantation
(rabbits, dogs)
ROlHL-08696-15 0014 Orthotopic heart transplantation ■
Transplantation immunology-Cardiac retransplantation
(dogs)
R01HL-08e96-15 0018 Orthotopic heart transplantation -
Training in cardiac transplantation
R01HL08696-15 0019 Orthotopic heart transplantation ■
Suppressor cell stimulation (dogs, mice)
ROlHL-08696-15 0020 Orthotopic heart transplantation -
Complete cardiopulmonary transplantation (dogs)
POlHL-090 11-15 0013 A research and resource program
in blood - A quantitative study of immunological
enhancement (mice)
POlHL-12738-10 0130 Physiologic pharmacology and its
clinical applications - Compatibility enhancement during
cardiac allografting (dogs)
POlHL-13108-09 Clinical heart transplantation
P01HL-I3108-09 0001 Clinical heart transplantation -
Therapy and prognosis (human)
P01HL13108-09 0002 Clinical heart transplantation -
Preoperative immunologic studies of cardiac recipients
POlHL-13108-09 0003 Clinical heart transplantation -
Endomyocardial biopsy pathology
POlHL-1 3 108-09 0009 Clinical heart transplantation ■ B
cell alloantigens in cardiac allograft compatibility (human)
P01HL1310809 0010 Clinical heart transplantation -
Serum factors inhibiting lymphocyte responses in MLC
(human, bush babies)
POlHL-13108-09 OOU Clinical heart transplantation ■
Humoral and cellular kinetics of allograft rejection (human)
POlHL-13108-09 0012 Clinical heart transplantation -
Human T cell sheep erythrocyte receptors
POlHL-13108-09 0014 Clinical heart transplantation -
Platelets and coagulation in accelerated graft coronary
atherosclerosis
POlHL-13108-09 0015 Clinical heart transplantation •
Antithymocyte globulin analysis and clinical effects
P01HL13108-09 0016 Clinical heart transplantation -
Total lymphoid irradiation for immune response (dogs)
POlHL-13108-09 0017 Clinical heart transplantation -
Electrophysiology of the transplanted denervated human
heart
R01HL13323-08 Intrarenal pressure and renal function
(human, dogs)
POIHL- 137 38-08 0004 Cardiac assist devices and
artificial hearts ■ Hematological evaluation of prosthetic
materials (calves)
POlHL-1373808 0005 Cardiac assist devices and
artificial hearts - Development of new materials for
artificial heart and assist devices (sheep, dog)
ROIHL 13987-04 Transplantation of the lung (dogs)
ROlHL-1479907 Cardiac heterotransplantation-
Immunologic modification (mice, rat)
ROlHL-1512405 Genesis of hypertension in renal disease
(human, dogs)
ROlHL-161 19-05 Spleen and marrow allografts in
hereditary anemia (mice)
POIHL 16387-04 0006 The blood vessel and
thrombogenesis - Mechanism of delayed vessel graft failure
(dogs, rabbits)
R01HL16642-05 Biochemistry and pathophysiology of
plasma kallikrein (human, animals)
P60HL17265-04 0006 Community blood resource center
support - Research-Evaluation of platelet transfusions
(human, dog)
P60HL 17265-04 0009 Community blood resource center
support Research-Developing granulocyte transfusion
therapy (human, rabbit)
'Excludes routine methodology OR rovers only general projects which preclude indexing at the specific level.
••Onented significantly to above subject.
TIS
** P60HL-1 7269-04 0033 National heart and blood vessel
research and demonstration center - Autoallergic response
in cardiomyopathy, atherosclerosis, rheumatic heart disease
** P01HL1741705 0001 Experimental lung transplantation
- Mechanisms and mediators of lung allograft rejection
(dogs, mice)
** POlHL-17417-05 0004 Experimental lung transplantation
- Methods for suppressing lung allograft rejection (dogs,
mice)
ROlHL-1799304 0002 Ventricular dynamics from
surgically inserted markers - Left ventricle function In
human cardiac allograft
ROlHL-18007-05 Neural mechanisms controling motor act
of breathing (cats, human)
** ROlHL-18186-04 Cardiac allografts in autologous
radiation chimeras (rats, dogs)
** ROIHL 1851903 Albumin, endothelium and
hemocompatibility (human, dog, cattle, rabbit)
M POlHL-18646 03 Studies basic to heart transplantation
** POlHL-1864603 0001 Studies basic to heart
transplantation - Individualized regulation of
immunosuppression (dogs, rats)
** P01HL18646-03 0002 Studies basic to heart
transplantation - Detection of rejection (dogs)
** P01HL18646 03 0006 Studies basic to heart
transplantation - Reduction or elimination of existing
presensitization (human, animals)
** P01HL18646-03 0008 Studies basic to heart
transplantation - Immunophysiology and early detection of
rejection (dogs)
POlHL-1864603 0009 Studies basic to heart
transplantation - Pathologic aspects of cardiac allograft
rejection (sheep, dogs)
POlHL-18827-02 0006 Platelet vessel wall interactions In
thrombogenesis - Platelet immune injury in man
P50HL-18828-03 0006 Specialized center of research In
thrombosis - Etiology and pathogenesis of atherosclerosis
(rabbit, monkey, rat, human)
" ROlHL-18936-02 Heart preservation and transplantation
studies (rat)
R01HL19333-03 Hematopoietic chimerism (mice, monkey)
ROlHL-20354-02 Direct determination of oxygen tension in
the clinical environment (human, dogs)
ROlHL-22301-01 Immunogenetics of chronic pulmonary
inflammation (mice)
** R23HL-22448-01 Modulation of heart graft antigenicity by
pertusion (rats)
" ROlHL'22456-01 Lipoproteins in bioregulation of the
immune response (mice, human)
TISSUE COMPATIBILITY-TRANSPLANT,
RETRANSPLANTATION
** ROlHL-08696-15 0014 Orthotopic heart transplantation -
Transplantation immunology -Cardiac retransplantation
(dogs)
POIHL- 18646-03 0008 Studies basic to heart
transplantation - Immunophysiology and early detection of
rejection (dogs)
TISSUE COMPATIBILITY-TRANSPLANT,
TRANSPLANTATION
SEE ALSO BLOOD AND RE SYSTEM, BONE MARROW
TRANSPLANTATION
SEE ALSO BLOOD AND RE SYSTEM, SPLEEN TISSUE (CELLS)
TRANSPLANTATION
SEE ALSO BLOOD TRANSFUSION
SEE ALSO ENDOCRINOLOGY, ENDOCRINE TRANSPUNTATION
SEE ALSO HEART TRANSPUNTATION
SEE ALSO KIDNEY TRANSPLANTATION
SEE ALSO NEOPLASMS TRANSPLANTATION
SEE ALSO PREGNANCY, EMBRYO-FETUS TRANSPLANTATION
SEE ALSO SKIN TRANSPLANTATION
SEE ALSO TISSUE DONORS
SEE ALSO TISSUE PRESERVATION
** P01HL-06664-17 0042 Cardiopulmonary function In
remediable vascular disease - Physiologic studies on vein
grafts (dogs)
ROIHL- 194 19-03 Cellular interactions with foreign
materials (mammals)
ROlHL-20554-02 Memory-alloy-filters for venous emboli
(dogs)
TISSUE COMPATIBILITY-TRANSPLANT,
TRANSPLANTATION AUTOLOGOUS
POlHL-06312-17 0015 Surgical cardiology - Internal
mammary artery versus saphenous vein for coronary artery
bypass (human)
POlHL-06312-17 0029 Surgical cardiology - Cardiac
lymphatics in the transplanted heart (dogs)
POlHL-06835-17 0061 Cardiovascular disease - Studies
in renal physiology (human, rats, dogs)
ROlHL-11945-10 Synthesis of artificial lung and kidney
systems (sheep, mice, swine)
** POlHL-13737-07 0033 Assisted circulation - Autologous
bioprosthetic grafts for coronary artery bypass surgery
(human, dogs)
ROlHL-14126-17 Effect of function on grafts and implants
of collagen (dogs, monkeys)
ROlHL-15448-06 Surgical and metabolic aspects of
venous grafts, (dogs, monkeys, rabbits)
POlHL-16387-04 0006 The blood vessel and
thrombogenesis • Mechanism of delayed vessel graft failure
(dogs, rabbits)
(contd)
M Grant has subproiects descnbing specific research aspects.
See Appendix for investigator's name and grant number.
TIS
ROIHL 1736904 Artenal bypass sufjeiK Sliucluie and
metabolism (monKeys)
PO\Hl IMUOb 0004 Enpenmental lung liansplantation
Methods lot supptessinj luns allogralt rejection (dogs,
mice)
POIHI W4170& 0005 Experimental luns tiansplaritation
Lung transplantation in bilateral emphysema (dogs)
POIHI 17417 Ob 0006 Experimental lung transplantation
Bronchial anastomotic problems and increases donor lung
availability (dog)
*• ROIHL 18186 04 Cardiac allogtatts in autologous
radiation chimeras (rats, dogs)
ROIHL 221 10 02 Healing complications in vascular
gratling (dogs)
NOIHV 12060 18 Tissue cultured endothelium tor vascular
prosthetic devices (human, animals)
TISSUE COMPATIBIUTY-TRANSPIANT,
TRANSPLANTATION HETEROLOGOUS
R01HL01623 24 Antigens related to graft rejection
(rabbits, rats)
P01HL06370 17 0013 Cardiopulmonary and renal
pathology research center Motphologrc analysis of
vascular prosthesis (human, dogs)
P01HL06370-17 0014 Cardiopulmonary and renal
pathology research center Quantitatrve morphology rn
cardiac disease (human, rats, dogs)
•• R01HL08696-15 0013 Orthotopic heart transplantation •
Transplantation immunology-Cardiac heterotransplantation
(rabbits, dogs)
R01HL0869615 0019 Orthotopic heart transplantation ■
Suppressor cell stimulation (dogs, mice)
R01HL0869615 0020 Orthotopic heart transplantation -
Complete cardiopulmonary transplantation (dogs)
POlHL-1237310 0003 Cardiopulmonary physiology and
pathophysiology - Myocardial function in man
** ROlHL-14799-07 Cardiac heterotransplantation-
Immunologic modification (mice, rat)
*• P60HL-15160-07 0011 Center for sickle cell disease -
Study of human sickle cells in an animal model (rats)
•* POlHL-18646-03 0003 Studies basic to heart
transplantation - Host responses to xenografts (rodents,
rabbits)
POlHL-18646-03 0008 Studies basic to heart
transplantation - Iramunophysiology and early detection of
rejection (dogs)
P01HL18646-03 0009 Studies basic to heart
transplantation - Pathologic aspects of cardiac allograft
rejection {sheep, dogs)
ROlHL-19246-03 Regression of cardiac hypertrophy -
Myocardial and renal (human)
ROlHL-20037-02 Left ventricular-aortic bypass and
composite prosthesis (sheep, swine, cattle)
NOlHV-72939-01 Develop and evaluate left heart assist
blood pumps (human, calves, pigs)
TISSUE COMPATIBILITY-TRANSPLANT,
TRANSPLANTATION HOMOLOGOUS
ROlHL-01623-24 Antigens related to graft rejection
(rabbits, rats)
ROlHL-01803-23 0010 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Atherosclerosis induction-Graft rejection
and hypercholesterolemia (rabbits)
POlHL-06312-17 0017 Surgical cardiology - Cardiac
transplantation (human)
POlHL-06312-17 0018 Surgical cardiology - Cardiac
transplantation grovrth (calves)
POlHL-06312-17 0022 Surgical cardiology - Cardiac
transplant-Experimental simultaneous heart and kidney
transplant (dogs)
POlHL-06370-17 0001 Cardiopulmonary and renal
pathology research center - The humoral and cellular
mechanisms of allograft rejection (monkeys)
POlHL-06370-17 0004 Cardiopulmonary and renal
pathology research center - Lymphocytes in graft rejection
and immune surveillance (human)
ROlHL-08696-15 0001 Orthotopic heart transplantation -
Transplantation immunology-Antithymocyte globulin
(rabbits, monkeys)
R01HL08696-15 0004 Orthotopic heart transplantation ■
Transplantation immunology-Avian antibody studies
(chickens, rats, rabbits)
R01HL08696-15 0012 Orthotopic heart transplantation -
Transplantation immunology -Modulation of donor
antigenicity (dogs)
ROlHL-08696-15 0014 Orthotopic heart transplantation -
Transplantation immunology-Cardiac retransplantation
(dogs)
ROlHL-08696-15 0019 Orthotopic heart transplantation -
Suppressor cell stimulation (dogs, mice)
ROlHL-08696-15 0020 Orthotopic heart transplantation -
Complete cardiopulmonary transplantation (dogs)
POlHL-09011-15 0013 A research and resource program
in blood - A quantitative study of immunological
enhancement (mice)
** POlHL-12738-10 0130 Physiologic pharmacology and its
clinical applications - Compatibility enhancement during
cardiac allografting (dogs)
M P01HL13108-09 Clinical heart transplantation
** POlHL-13108-09 0001 Clinical heart transplantation ■
Therapy and prognosis (human)
** POlHL-13108-09 0002 Clinical heart transplantation -
Preoperative immunologic studies of cardiac recipients
S13
• POIHI 13108 09 0003 Clinical heart transplantation
Endomyocardial biopsy pathology
• POIHI 1310809 0008 Clinical heart transplantation -
Physiology and pharmacology of the transplanted human
heart
• POIHI 13108 09 0009 Clinical heart transplantatron B
cell alloanligens in cardiac allograft compatibility (human)
• POIHL 1310809 0010 Clinical heart transplantation
Serum factors inhibiting lymphocyte responses in MIC
(human, bush babres)
• POIHL 13108 09 0011 Clinical heart transplantation
Humoral and cellular kinetics of allograft reiection (human)
'* POIHL 1310809 0012 Clinical heart transplantation
Human T cell sheep erythrocyte receptors
'* POIHL 1310809 0014 Clinical heart transplantation
Platelets and coagulation in accelerated graft coronary
atherosclerosis
'♦ POlHL-1310809 0015 Clinical heart transplantation -
Antithymocyte globulin analysis and clinical effects
•* POIHL 1310809 0016 Clinical heart transplantation
Total lymphoid irradiation for immune response (dogs)
** POIHL 13108-09 0017 Clinical heart transplantation -
Electrophysiology of the transplanted denervated human
heart
•* POlHL-13108-09 0018 Clinical heart transplantation -
Electrophysiologic studies of cardiac drugs in the
denervated heart
** POlHL-13108-09 0019 Clinical heart transplantation -
Effect of autonomic nervous system on arrhythmias
(human)
** P01HL13108-09 0020 Clinical heart transplantation -
Autonomic neural studies in the denervated heart (human)
** POlHL-1310809 0021 Clinical heart transplantation -
Autonomic reflex regulation of ventricular function (human)
** POlHL-13108-09 0022 Clinical heart transplantation -
Studies on cardiac receptors (human)
" POlHL-1310809 0023 Clinical heart transplantation ■
Adaptive mechanisms of the denervated heart (human)
** POlHL-1310809 0024 Clinical heart transplantation -
Response of denervated heart to stress -Noninvasive
(human)
ROlHL-13323-08 Intrarcnal pressure and renal function
(human, dogs)
ROlHL-13987-04 Transplantation of the lung (dogs)
ROlHL-14126-17 Effect of function on grafts and implants
of collagen (dogs, monkeys)
R01HL-1491306 Hypertension -Genetic influence of kidney
(rats)
ROlHL-161 19-05 Spleen and marrow allografts in
hereditary anemia (mice)
POlHL-16387-04 0003 The blood vessel and
thrombogenesis - Blood vessel healing (rabbits)
POlHL-16387-04 0006 The blood vessel and
thrombogenesis - Mechanism of delayed vessel graft failure
(dogs, rabbits)
P60HL- 172 69-04 0033 National heart and blood vessel
research and demonstration center - Autoallergic response
in cardiomyopathy, atherosclerosis, rheumatic heart disease
** P60HL-17269-04 0034 National heart and blood vessel
research and demonstration center ■ Immunologic
enhancement of cardiac allografts (mice)
M POlHL-17417-05 Experimental lung transplantation
** P01HL17417-05 0001 Experimental lung transplantation
- Mechanisms and mediators of lung allograft rejection
(dogs, mice)
** POlHL-17417-05 0003 Experimentallung transplantation
- Methods for detecting lung allograft rejection (dogs)
POlHL-17417-05 0004 Experimental lung transplantation
- Methods for suppressing lung allograft rejection (dogs,
mice)
POIHL- 174 17-05 0005 Experimental lung transplantation
- Lung transplantation in bilateral emphysema (dogs)
POlHL-17417-05 0006 Experimental lung transplantation
- Bronchial anastomotic problems and increases donor lung
availability (dog)
ROlHL-17749-03 Adrenocortical factors in human
hypertension (human)
ROlHL-17902-04 Mammalian renal microcirculation
(hamsters)
ROlHL-17947-04 Experimental renal and neurogenic
hypertension (human, animals)
ROlHL-17993-04 0002 Ventricular dynamics from
surgically inserted markers - Left ventricle function in
human cardiac allograft
** ROlHL-181 86-04 Cardiac allografts in autologous
radiation chimeras (rats, dogs)
M POlHL-18646-03 Studies basic to heart transplantation
** POlHL-18646-03 0001 Studies basic to heart
transplantation - Individualized regulation of
immunosuppression (dogs, rats)
POIHL- 186 46-03 0002 Studies basic to heart
transplantation ■ Detection of rejection (dogs)
POlHL-18646-03 0004 Studies basic to heart
transplantation - Presensitization -Detection, incidence and
clinical significance
POlHL-18646-03 0008 Studies basic to heart
transplantation - Immunophysiology and early detection of
rejection (dogs)
** POlHL-18646-03 0009 Studies basic to heart
transplantation - Pathologic aspects of cardiac allograft
rejection (sheep, dogs)
TIS
POIHL 18646 03 0010 Studies basic to heart
transplantation DevalopmanI and itudy of a heart
preservation chamber (dogs, sheep)
P50HL 18828 03 0006 Specralrjed center of research in
thrombosis Etiology and pathogeneiii of alheroscleroiu
(rabbit, monkey, rat. human)
ROIHL 18936 02 Heart preservation and transplantation
studies (rat)
ROIHL 221 10 02 Healing complications in vascular
grafting (dogs)
TISSUE COMPATIBILITY -TRANSPLANTATION
RESOURCES, REFERRAL CENTERS AND
REGISTRIES
•• t<01HB 62963 03 International bone marrow transplant
registry
•• NOIHB 62964 03 International bone marrow transplant
registry
NOIHV 12054 14 Development of intimal linings (human,
cattle)
TISSUE CULTURE
SEE TISSUE (CELL) CULTURE*
TISSUE DONORS
SEE ALSO BLOOD TRANSFUSION. BLOOO DONORS
POlHL-06312 17 0022 Surgical cardiology Cardiac
transplant -Experimental simultaneous heart and kidney
transplant (dogs)
POIHL 06314-17 0061 Immunologic mechanisms in
cardiovascular disease Role of viruses in cardiovascular
and renal disease (human, mice)
ROlHL-0869615 0004 Orthotopic heart transplantation -
Transplantation immunology-Avian antibody studies
(chickens, rats, rabbits)
** ROlHL-08696-15 0012 Orthotopic heart transplantation
Transplantation immunology -Modulation of donor
antigenicity (dogs)
ROlHL-08696-15 0013 Orthotopic heart transplantation -
Transplantation immunology -Cardiac heterotransplantation
(rabbits, dogs)
ROlHL-08696-15 0020 Orthotopic heart transplantation -
Complete cardiopulmonary transplantation (dogs)
POlHL-12738-10 0130 Physiologic pharmacology and its
clinical applications - Compatibility enhancement during
cardiac allografting (dogs)
M POIHL- 1310809 Clinical heart transplantation
POlHL-13108-09 0001 Clinical heart transplantation -
Therapy and prognosis (human)
** POlHL-13 108-09 0002 Clinical heart transplantation -
Preoperative immunologic studies of cardiac recipients
** POlHL-13108-09 0009 Clinical heart transplantation - B
cell alloanligens in cardiac allograft compatibility (human)
ROlHL-14913-06 Hypertension-Genetic influence of kidney
(rats)
POlHL-18646-03 0003 Studies basic to heart
transplantation - Host responses to xenografts (rodents,
rabbits)
POIHL- 18646-03 0004 Studies basic to heart
transplantation - Presensitization-Detection, incidence and
clinical significance
R23HL-22448-01 Modulation of heart graft antigenicity by
perfusion (rats)
TISSUE FACTOR (TISSUE THROMBOPLASTIN)
SEE BLOOD COAGULATION. THROMBOPUSTIN
TISSUE MOSAICISM
** POlHL-03 174-23 0006 Mechanisms of acute vascular
reaction to injury - Atherosclerotic plaque studies using
mosaic analysis (human)
ROlHL-13987-04 Transplantation of the lung (dogs)
** ROlHL-18186-04 Cardiac allografts in autologous
radiation chimeras (rats, dogs)
** ROlHL-19333-03 Hematopoietic chimerism (mice, monkey)
POlHL-20993-02 0003 Population dynamics of arterial
cells in atherogenesis • Clonal phenomena in atherogenesis
(human, hares)
TISSUE PRESERVATION
SEE ALSO BLOOD PRESERVATION
SEE ALSO CARDIOVASCULAR TISSUE PRESERVATION
SEE ALSO HEART PRESERVATION
SEE ALSO KIDNEY PRESERVATION
SEE ALSO RESPIRATORY SYSTEM PRESERVATION, LUNG
PRESERVATION
SEE ALSO TISSUE RESOURCES, REGISTRIES
** POlHL-06312-17 0033 Surgical cardiology - Studies in
cryopreservations (rats)
ROlHL-0869615 0012 Orthotopic heart transplantation -
Transplantation immunology-Modulation of donor
antigenicity (dogs)
ROlHL-15520-06 Total blood replacement by fluorocarbons
and polyols (rats)
N01HV-12054-14 Development of intimal linings (human,
cattle)
TISSUE RESOURCES, REGISTRIES
SEE ALSO BLOOD PRESERVATION, BLOOD BANKS, CENTERS-
RESOURCES-REGISTRIES
SEE ALSO TISSUE (CELL) CULTURE, CELL CULTURE
COLLECTIONS BANKS AND REGISTRIES
** R01HL-05694-20 Functional pathology of cardiovascular
disease (human)
(contd)
•Excludes routine methodology OR covers only general projects which preclude
"Oriented significantly to above subject.
indexing at the specific level.
M Grant has subprojeds describing specific research aspects.
See Appendix for investigator's name and grant number.
TIS
** NOlHR-62930-03 Lung cell resource facility
NOlHR-6294305 Nocturnal oxygen therapy in chronic
hypoxic lung disease (human)
TISSUE RESPIRATION
SEE RESPIRATION INTERNAL
TISSUE SPACES
SEE BODY FLUIDS, TISSUE SPACES
TISSUE SUPPORTING FRAMES
SEE BIOMATERIALS. TISSUE SUPPORTING FRAMES
TOADS AND FROGS
SEE AMPHIBIANS, ANURANS*
TOBACCO AND TOBACCO PRODUCTS
SEE CONSUMER PRODUCTS, TOBACCO AND TOBACCO
PRODUCTS
TOCOPHEROL DEFICIENCY
SEE NUTRITIONAL ABNORMALITIES, HYPOVITAMINOSIS E
TOCOPHEROLS
SEE VITAMIN E
TOFRANIL
SEE A2EPINES, IMIPRAMINE
TOLAZOLINE
SEE IMIDAZOLES, TOLAZOLINE
TOLBUTAMIDE
SEE SULFONYLUREA, TOLBUTAMIDE
TOLERANCE
SEE CARBOHYDRATE BALANCE, GLUCOSE TOLERANCE
SEE DRUGS TOLERANCE
SEE IMMUNITY, IMMUNOLOGICAL UNRESPONSIVENESS
TOMOGRAPHY
SEE RADIOGRAPHY, TOMOGRAPHY*
TOMOGRAPHY, RADIOISOTOPE
SEE RADIOAUTOGRAPHY, RADIOISOTOPE TOMOGRAPHY*
TOOTH ERUPTION
SEE DENTAL DEVELOPMENT
TOXEMIA, MICROBIAL TOXINS
SEE BLOOD TOXICOLOGY, BACTEREMIA-SEPTICEMIA
TOXEMIAS OF PREGNANCY
SEE PREGNANCY TOXEMIAS AND HYPERTENSION
TOXIC MECHANISMS AND REACTIONS IN
HYPERSENSITIVITY
SEE HYPERSENSITIVITY, TOXIC REACTIONS AND MECHANISMS
IN HYPERSENSITIVITY
TOXIC REACTIONS AND MECHANISMS IN
IMMUNOLOGY
SEE IMMUNOLOGY, TOXIC REACTIONS AND MECHANISMS IN
IMMUNOLOGY
TOXIC SHOCK
SEE INJURIES. SHOCK, TOXIC
TOXICANT METABOLISM
SEE TOXICOLOGY, TOXICANT METABOLISM
TOXICANT SCREENING
SEE TOXICOLOGY. TOXICANT SCREENING
TOXICOLOGY
SEE ALSO AIR POLLUTION
SEE ALSO BLOOD TOXICOLOGY
SEE ALSO ENVIRONMENTAL HEALTH, CONTAMINATION
(GENERAL)
SEE ALSO HYPERSENSITIVITY, TOXIC REACTIONS AND
MECHANISMS IN HYPERSENSITIVITY
SEE ALSO INJURIES, SHOCK, TOXIC
SEE ALSO PESTICIDES BIOLOGICAL EFFECTS (GENERAL)
ROlHL-0750213 Phytochemistry of the genus fhalictrum
(dogs, plants)
** R01HL099I1I2 Hormonal and dietary modification of
NaCI toxicity (rats) mice;
ROIHL 1339916 Heme protein structure and function
(human, horse, plants, bacteria)
P01HL16117-05 0007 Ion movements and membranes in
cardiovascular control - Physiological and molecular
properties of ionophores (dogs, rabbits)
ROlHL-16643-02 Fluorocarbon emulsions as artificial
blood (animals)
P50HL-19156-02 0003 Pulmonary SCOR-Chronic diseases
of airways Powdered tantalum to study airway morphology
and mucociliary clearance (human)
TOXICOLOGY, ANIMAL POISONS
SEE ALSO CARDIAC GLYCOSIDES AGLYCONES,
BUFADIENOLIDES
R01HL-22201-01 Pharmacology and chemistry of
nudibranch toxins (guinea pigs, rats, mice)
TOXICOLOGY, ANIMAL POISONS, ARTHROPOD
SEE ALSO TOXICOLOGY, ANIMAL POISONS, INSECTS BITES
STINGS VENOMS
ROlHL-22239-01 The molecular basis of electrical
excitability (chick embryos, rats)
514
TOXICOLOGY, ANIMAL POISONS, ARTHROPOD,
SPIDER
** R01HL-2220101 Pharmacology and chemistry of
nudibranch toxins (guinea pigs, rats, mice)
TOXICOLOGY, ANIMAL POISONS,
BATRACHOTOXIN
ROIHL'22239-Ol The molecular basis of electrical
excitability (chick embryos, rats)
TOXICOLOGY, ANIMAL POISONS, INSECTS BITES
STINGS VENOMS
** P01HL-10342-13 0028 The integrated function of
respiration and circulation - Mediator release,
hemodynamics and respiratory function In anaphylaxis
(dogs)
TOXICOLOGY, ANIMAL POISONS, REPTILE
ROlHL-03424-21 Formation and properties of prothrombin
derivatives (human, animals)
POlHL-16251-Oe 0010 Membrane-bound enzymes in heart
and other tissues - Reversible activation of L-amino acid
oxidase (snakes)
POlHL-16769-05 0002 Pathobiologic and host defense
reactions in the lung ■ Pathogenesis of complement
dependent injury to the lungs (rabbits)
ROlHL-19538-03
agents
ROlHL-20199-02
in the rat
ROlHL-22875-01
Synthesis of potential antihypertensive
Drug-induced alterations in infarct size
Crotalase-Cheraistry, physiology, clinical
potential (rats, rabbits)
** ROlHL-22996-01 Venom proteases -Action on plasma
protease inhibitors (human)
TOXICOLOGY, ANIMAL POISONS,
TETRODOTOXIN
POlHL-12738-10 0080 Physiologic pharmacology and its
clinical applications - Electrophysiology of cardiac muscle
in the mitral valve (monkeys)
ROlHL-13306-08 Pharmacological control of cardiac
membrane currents (cattle, rabbits)
ROlHL-13339-08 Pharmacology of developing cardiac
tissues (chick embryo)
ROlHL-16567-04 Differentiation of the heart-cell
membrane (mice, chick)
ROlHL-21371-02 Energy loss microanalysis of myocardial
cations
ROlHL-22239-01 The molecular basis of electrical
excitability (chick embryos, rats)
R01HL-22568-01 pH effect in heart cells -Influence of
cardiac drugs (tissue culture, rats)
TOXICOLOGY, ANIMAL POISONS, VENOMS
** P01HL-06350-I7 0020 Hemostasis research program
project - Structure and function of coagulant venom
proteases
POlHL-06370-17 0014 Cardiopulmonary and renal
pathology research center - Quantitative morphology in
cardiac disease (human, rats, dogs)
ROlHL-10582-12 Thrombosis and hemostasis-Analysis,
methods and standards (human, cattle, venom)
P01HL-1I310-12 0096 Mechanisms of cardiovascular
disease - Complement chemistry and biology (human,
rabbits)
ROIHL-16233-05 Molecular cardiology of MDP-induced left
ventricular failure (dogs)
POlHL-164 11-04 0001 Blood systems in coagulation and
vessel disease - Molecular studies of the role of
complement in blood coagulation (human, rabbits)
POlHL-16769-05 0002 Pathobiologic and host defense
reactions in the lung - Pathogenesis of complement
dependent injury to the lungs (rabbits)
POlHL-18576-03 0007 Thrombosis research program
project • Relationships between coagulability and
thrombosis (human, animals)
ROlHL-21975-01 Studies on normal and abnormal factor
IX (human, dogs, cows)
** ROlHL-22996-01 Venom proteases-Action on plasma
protease inhibitors (human)
TOXICOLOGY, CYTOTOXICITY
SEE ALSO IMMUNOLOGY, ANTIBODIES, AGGLUTININS
ROlHL-03919-20 The cell suface of streptococci (rats,
human)
POlHL-06314-17 0066 Immunologic mechanisms in
cardiovascular disease • Sensitization, cell-mediated
cytotoxicity, role of lymphocytes (human, mice)
** POlHL-0637017 0006 Cardiopulmonary and renal
pathology research center - Chemical basis of
ultrastructural changes in disease (rats)
POlHL-08214-15 0023 Chemical and biological properties
of lipids - Lipids in microorganisms and cell cultures
(hamsters, mosquitoes)
POlHL-13 108-09 0011 Clinical heart transplantation -
Humoral and cellular kinetics of allograft rejection (human)
POlHL-13108-09 0012 Clinical heart transplantation -
Human T cell sheep erythrocyte receptors
P01HL13108-09 0013 Clinical heart transplantation -
Cardiomyopathic lymphocyte responsiveness to cultured
endothelium
ROlHL-13645-11 Tryptophan-induced pulmonary
emphysema (cattle, goats, rabbits)
•Excludes routine melhodotojy OR covers only general projects which preclude indexing
•*Oii*nted significanthr to above subject.
at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
TOX
P50HL-142 12-07 0006 Correlated studies of pulmonary
fibrosis - Alveolar macrophage physiology (human, rodents,
rabbits)
P50HL-14212-07 0013 Correlated studies of pulmonary
fibrosis - Mechanism of beryllium pathogenicity in the lung
(human, rabbit, guinea pig)
** P50HL-15061-07 0012 Response of lung to injury -
Hyperbaric oxygen, carbon monoxide, and ozone or peroiide
toxicity (rats)
POlHL-16748-05 0002 Cellular and immunological basis
of pulmonary diseases - Immunological function of alveolar
macrophages (rabbits, sheep, mice)
POlHL-16769-05 0003 Pathobiologic and host defense
reactions in the lung - Pathobiologic mechanisms of
delayed sensitivity reactions in the lung (animals)
ROIHL- 17404-05 Immunologic mechanisms in heart
disease (mice)
ROIHL- 17826-04 Oxygen delivery to tissue (rat, dog)
ROIHL- 17844-04 Artificial blood substitutes-02-binding
iron chelates (human, mammals)
ROlHL-18259-03 Controlled intratissue release of
prostaglandins
ROlHL-18731-02 RES stimulating materials in
experimental shock (dogs)
ROlHL-19234-03 Streptococci and heart-Cell-niediated
cross-reaction (mice)
ROlHL-19333-03 Hematopoietic chimerism (mice, monkey)
** R23HL-19584-01 Alveolar macrophage responses to toxic
particle exposure (guinea pigs, human)
ROlHL-20125-02 Cyclic nucleotides and alveolar
macrophage activation (rabbits)
ROIHL 20533-09 Pathogenesis of rheumatic fever (human,
rabbits)
** POlHL-20993-02 0008 Population dynamics of arterial
cells in atherogenesis - Angiotoxicity of cholesterol
oxidation in atherogenesis (rabbits)
ROlHL-21009-02 Effects of air pollutants on lung cells in
culture (rats)
R23HL-2 11 16-02 Mechanisms of membrane and tissue
damage in lung (dogs, rabbits)
** R23HL-21327-02 Molecular mechanisms of chemical
myocardiopathies (rats)
POlHL-22602-01 0001 Pathophysiology of the
endothelium - Platelet-endothelial interactions in vitro
(human, cattle)
POlHL-22602-01 0003 Pathophysiology of the
endothelium - Mechanisms of endothelial proliferation
(human, animals)
ROlHL-23631-01 Immunogenetic factors in allergic
respiratory diseases (human)
TOXICOLOGY, ENVIRONMENTAL
SEE ALSO AIR POLLUTION
SEE ALSO PHYSICAL AND/OR CHEMICAL AGENTS
INTERACTION (BIOLOGICAL AND ECOLOGICAL)
SEE ALSO PHYSICAL ANO/OR CHEMICAL AGENTS
INTERACTION (BIOLOGICAL AND ECOLOGICAL),
POLLUTANTS INTERACTION
POlHL-06370-17 0006 Cardiopulmonary and renal
pathology research center - Chemical basis of
ultrastructural changes in disease (rats)
POlHL-08214-15 0005 Chemical and biological properties
of lipids - Metabolism of lipids in animals
P50HL-14136-07 0016 Pulmonary SCOR-Airways
obstructive diseases - Environmental factors in airways
obstructive diseases (human)
** P50HL-14212-07 0013 Correlated studies of pulmonary
fibrosis - Mechanism of beryllium pathogenicity in the lung
(human, rabbit, guinea pig)
P50HL-15061-07 0002 Response of lung to injur> -
Oxidative metabolism, phospholipid synthesis, and response
to toxins (rats)
** P50HL-1 5092-07 0010 Immune and fibratic response to
occupational environments - Characterization of toluene
diisocyanate in industrial environments
** P50HL-15389-07 0009 Pulmonary SCOR-Hypersensitivity
pneumonitis - Clinical studies-Pulmonaiy mycotoxicosis
** P50HL-15389-07 0013 Pulmonary SCOR-Hypersensitivity
pneumonitis - Animal model-Pulmonary mycotoxicosis
(rabbit, guinea pig)
R01HL-16029-05 Bio-organic chemistry of ozone, nitrogen
dioxide and tobacco smoke
R01HL16674-05 Airborne metals and lung permeability
(bullfrogs, rats)
** P50HL-19170-02 0005 Harvard pulmonary SCOR-Chronic
diseases of the airways - Pulmonary toxicology of plastics
intermediates and pyrolysis products (animal)
R23HL-19584-01 Alveolar macrophage responses to toxic
particle exposure (guinea pigs, human)
ROlHL-19720-03 Evaluation of anfi-fibrotic agents in
pulmonary fibrosis (rats)
R01HL-21008-02 Effect of pollutants on organotypic lung
cultures (rats)
ROlHL-2 1009-02 Effects of air pollutants on lung cells in
culture (rats)
TOXICOLOGY, GAS POISONING, CARBON
MONOXIDE
POlHL-10342-13 0011 The integrated function of
respiration and circulation - Control of respiration 1-
Peripheral chemoreceptor studies (cats)
(contd)
TOX
■* P01HI'I0342'I3 0014 Tha InUiritad function of
resplratton and circulation 0«yg«n and carbon monxide
transfer (humanp dogs, sliaap)
POIHL 10342 13 0024 The integrated function of
respiration and circulation Cytochrome P450 and
physiological response to hypoxia (rats)
POIHL 10342 13 0026 The integrated function of
respiration and circulation Control of respiration-
Charactarliation of the aortic body (cats)
•• P01H110342 13 0027 The Integrated function of
lesplratton and circulation Control of respiration-
Cardiovascular adjustment to hypoxia and carbon monoxide
ROlHL-121 74-11 Ventllation/perfusion distribution in the
lung (human, mammals)
P50HI 15061 07 0012 Response of lung to iniury
Hyperbaric oxygen, carbon monoxide, and Oione or peroxide
toxicity (rats)
ROIHL 15520-06 Total blood replacement by fluorocarbons
and polyols (rats)
ROlHL-23224-01 Hypoxia and pulmonary vascular smooth
muscle (rat. cat)
TOXICOIOOY, GAS POISONING, SMOKE
INHALATION
*• R23HL-2289501 Smoke Inhalation -Biochemical and
cellular responses (rabbits, bacteria)
TOXICOLOGY, MYCOTOXINS
SEE ALSO ALKALOIDS. ERGOT
*• P50HL- 15389-07 0009 Pulmonary SCOR-Hypersensitlvlty
pneumonitis - Clinical studies -Pulmonary mycotoxicosis
•* P50HL15389-07 0013 Pulmonary SCOR-Hypersensitivlty
pneumonitis - Animal model-Pulmonary mycotoxicosis
(rabbit, guinea pig)
TOXICOLOGY, MYCOTOXINS, CYTOCHALASIN
ROlHL-10503-13 Cardiac Ion transport and ultrastructure
(rats, guinea pigs, rabbits)
POlHL-15832-06 0012 Chemical-structural predispositions
to lung Injury - Contractile structures and contractility In
cells of lung respiratory tract
POlHL-18576-03 0001 Thrombosis research program
project - Platelet damage from physical forces and
artificial surfaces (human)
P01HL18708-03 0007 Oxygen, energy and contractility in
cardiac tissue - Surfaces, energy requirements, and
contractile proteins of cardiac cell in vitro
ROlHL-2064302 Analysis of heart cell contraction (rats)
ROlHL-21329-02 Beta-receptor regulation and cardiac
sites of drug action (cat. guinea pig. rat)
R01HL-22783-01 Hemodynamic induction of intlmal
fibromuscular lesion
R01HL-23010-01 Control and mechanism of platelet
aggregation (human)
TOXICOLOGY, PLANT POISONING, LATHYRISM
R01HL18918-03 Characterization of lung elastins (rat,
rabbit, chicken. Rhesus)
ROlHL-22208-02 Elastln structure, fibrogenesis and
disease (chickens, rabbits)
TOXICOLOGY, PLANT POISONS,
GRAYANOTOXINS
ROlHL-22239-01 The molecular basis of electrical
excitability (chick embryos, rats)
TOXICOLOGY, PLANT POISONS, PICROTOXIN
ROlHL-22715-01 Neural integration of the cardiovascular
reflexes (dogs))
TOXICOLOGY, POISON CONTROL AND
PREVENTION
*• ROlHL-21115-01 Prevention of 02 toxicity with superoxide
dismutase (rats)
TOXICOLOGY, PROTOZOAL TOXINS, SAXITOXIN
ROlHL-22239-01 The molecular basis of electrical
excitability (chick embryos, rats)
TOXICOLOGY, TOXICANT METABOLISM
ROlHL-19720-03 Evaluation of anti-fibrotic agents In
pulmonary fibrosis (rats)
TOXICOLOGY, TOXICANT METABOLISM,
DETOXICATION
SEE ALSO MCTAL COMPLEXES, LIGANOS. CHEUTING AGENTS
♦* POlHL-08682-15 0019 Regulation of the cardiovascular
system - Hepatic immunophysiology and host-defense in
shock (rat. dog. human)
P01HL-I6748-05 0004 Cellular and Immunological basis
of pulmonary diseases - Cellular and Immunological
processes In pulmonary defense systems
TOXICOLOGY, TOXICANT SCREENING
R01HL08696-15 0019 Orthotopic heart transplantation •
Suppressor cell stimulation (dogs, mice)
ROlHL-17479-04 Blood storage-The production of
cardlotoxlc material (dogs, human, swine)
** P50HL-19170-02 0005 Harvard pulmonary SCOR-Chronic
diseases of the airways - Pulmonary toxicology of plastics
Intermediates and pyrolysis products (animal)
TOXICOLOGY STUDY SECTION
** ROlHL-14127-16 Methemoglobinemia and antihypertensive
drugs (cats, mice, rats)
SIS
•• ROIHI 16079 OS Rio organic chemistry of ojone, nitrogen
•• r'thH WtI (fl^^r^oipiion of nonvolatile compounds
from the lung
•• ROIHL 18163 04 Red cell membrane effects due to
axidi2ing agents
•* ROIHL 20622 02 Pulmonary uptake and accumulation of
drugs (rabbits, rats)
♦• ROIHL 2100802 Effect of pollutants on organotypic lung
cultures (rats)
** ROIHL 2100902 Effects of air pollutants on lung cells in
culture (rats)
•• ROIHL 211 15-01 Prevention of 02 toxicity with superoxide
dismutase (rats)
•• ROIHL 22201 01 Pharmacology and chemistry of
nudibranch toxins (guinea pigs, rats, mice)
•• ROIHL 22259-01 Modification of susceptibility to oxygen
poisoning (rats)
♦* ROlHL-22875-01 Crotalase-Chemlstcy, physiology, clinical
potential (rats, rabbits)
•* ROIHL 22996-01 Venom proteases -Action on plasma
protease inhibitors (human)
TOXICOSIS, THYROTOXICOSIS
SEE THYROID GLAND DISORDERS, HYPERTHYROIDISM
TOXINS
SEE ALSO BLOOD TOXICOLOGY, HEMOTOXINS
SEE ALSO IMMUNOLOGY, ANTIGENS
SEE ALSO IMMUNOLOGY, ANTIGENS BACTERIAL
SEE ALSO IMMUNOLOGY, ANTITOXINS
SEE ALSO KIDNEY TOXINS, NEPHROTOXINS
SEE ALSO LIVER DISORDERS, TOXIC LIVER DISORDERS,
HEPATOTOXINS
SEE ALSO NEUROTOXINS
SEE ALSO RESPIRATORY DISORDERS, RESPIRATORY SYSTEM
TOXINS
SEE ALSO TOXICOLOGY, ANIMAL POISONS
SEE ALSO TOXICOLOGY, MYCOTOXINS
** P01HL11310-12 0102 Mechanisms of cardiovascular
disease - Cardiac membrane and Ion mobility (dogs)
ROlHL-1501307 Lung oxidative metabolism and energy
production (rodents, rabbits)
ROlHL-1595806 X-ray diffraction analysis of thrombin
and neurotoxin
POlHL-1611806 0004 Study of emphysema • Metabolic
activity of pulmonary connective tissue (human, hamsters)
ROlHL-1809704 Pathogenesis of acute renal failure (rats)
ROlHL-22562-02 Mechanism of cardiac action potential
propagation (tunicates)
TOXINS BACTERIAL
SEE IMMUNOLOGY, ANTIGENS BACTERIAL, BACTERIAL TOXINS
(GENERAL)
TOXINS HEMOTOXINS
SEE BLOOD TOXICOLOGY, HEMOTOXINS
TOXINS HEPATOTOXINS
SEE LIVER DISORDERS, TOXIC LIVER DISORDERS,
HEPATOTOXINS
TOXINS MYCOTOXINS
SEE TOXICOLOGY, MYCOTOXINS
TOXINS NEPHROTOXINS
SEE KIDNEY TOXINS, NEPHROTOXINS
TOXINS NEUROTOXINS
SEE NEUROTOXINS
TPNH-DIAPHORASE
SEE OXIDOREDUCTASES, NAD(P)H DEHYDROGENASE
(QUINONE)
TRA
SEE EYE, TRABECUUR MESHWORK
TRACE ELEMENTS
SEE CHEMICALS (GENERAL), ELEMENTS, TRACE ELEMENTS
TRACE ELEMENTS AND MINERALS IN THE DIET
SEE NUTRITION, DIETARY CONSTITUENTS, DIETARY TRACE
ELEMENTS AND MINERALS
TRACHEA
SEE RESPIRATORY SYSTEM, TRACHEA
TRACHOMA AGENT
SEE CHLAMYDIA. TRACHOMA AGENT
TRACKING TASK
SEE PSYCHOMOTOR FUNCTION, TRACKING TASK
TRACKING VISUAL
SEE PSYCHOMOTOR FUNCTION. VISUAL TRACKING
TRAINING
SEE EDUCATION, TRAINING
TRAINING, RELAXATION
SEE PSYCHIC ACTIVITY LEVEL. RELAXATION
TRAINING AIDS IN EDUCATION
SEE EDUCATION, AUDIOVISUAL AND OTHER TRAINING AIDS
TRAINING LEVEL
SEE EDUCATION, TRAINING LEVEL
TRA
TRANQUILIZERS
SEE PSYCHOPHARMACOIOGICAL AGENTS, TRANQUILIZERS
TRANSACETYLASE
SEE TRANSACYUSES
TRANSACYIASES
POIHL 06308 18 0040 Mechanisms and therapy of
circulatory disease Metabolism and fatty acid uliluation
Heart electrical stability (rats, dogs)
POIHI 06835 17 0015 Cardiovascular disease Plasma
cholesterol esterificalion in canine atherosclerosis
ROIHL 1286909 Arterial metabolism, diabetes and
atherogenesis (rats, rabbits)
ROIHL 14781 08 Lipid deposition in mammalian cells
(mice)
POIHL 16137 05 0004 Alveolar biology Subcellular
processes and controls in the surfactant system (animals)
ROIHL 17332-04 Use of the gut for therapy of coronary
artery disease (mammals)
ROIHL 18181-04 Surfactant metabolism -Alveolar cells and
lung disease (mice, rabbits)
ROlHL-18219-04 Regulation of cholesterol metabolism
(rats)
ROIHL 18938-03 Pulmonary fatty acid and phospholipid
metabolism (rats)
ROIHL 19010-03 Metabolism and cell biology of lung
surfactant system (rabbits, sheep)
POlHL-20948-02 0001 Molecular basis of cholesterol
metabolism - Biochemical and ultrastructural
characterization of LDL in human fibroblasts
POlHL-20948-02 0002 Molecular basis of cholesterol
metabolism - LDL pathway in cell lines with Informative
properties other than fibroblasts
ROlHL-2 1246-02 Roles of cholesterol and its metabolic
regulation (CHO cell mutants)
TRANSACYLASES, ACETYL COA
TRANSACETYLASE
ROlHL-1808904 Fatty acid metabolism in heart and its
regulation (swine, rats)
TRANSACYLASES, CHOLINE TRANSACYLASE
POlHL-14388-07 0185 Regulation of the circulation in
pathological states - Reflex control of venous tone (human,
rabbits, dogs)
POlHL-14388-07 0202 Regulation of the circulation in
pathological states - Development of hypertension in
spontaneously hypertensive rats
** POlHL-14388-07 0211 Regulation of the circulation in
pathological states - Choline acetyltransferase activity
(rats)
POlHL-14388-07 0213 Regulation of the circulation in
pathological states - Regulation of the heart and peripheral
circulation in heart failure
R01HL1483206 Myocardial cells-Autonomic and rhythmic
mechanisms (chick embryo, rats)
ROlHL-16066-05 Studies on neurogenic control of the
circulation (human, dogs)
POlHL-18974-03 0009 Experimental neurogenic
hypertension program - Biochemistry of brain tyrosine
hydroxylase (rats)
ROlHL-20768-02 Mechanisms of circulatory regulation in
heart failure (guinea pigs)
TRANSACYLASES, LECITHIN-CHOLESTEROL
TRANSESTERASES
** ROlHL-10642-18 Plasma cholesterol metabolism (human,
macaca)
ROlHL-14111-07 Cholesteryl esters In membranes and
atherosclerosis (human, swine)
P50HL-14197-07 0005 Support for center of research on
arteriosclerosis - Lipoprotein biosynthesis and degradation
in vivo and in vitro (human, animal)
** P50HL-14237-C7 0002 Support for arteriosclerosis center
- Interactions of lipoprotein particles with vascular surface
(human, rat)
P50HL-14237-07 0004 Support for arteriosclerosis center
- Synthesis, secretion of normal, abnormal plasma
lipoproteins (rodents, monkeys)
P50HL-15062-07 0001 Study of lipoproteins, artery wall.
and atherosclerosis - Structure and molecular interactions
of serum lipoproteins (human, monkey)
P50HL-15062-07 0008 Study of lipoproteins, artery wall,
and atherosclerosis - Lipid modifying enzymes (human,
monkey)
P50HL-15062-07 0009 Study of lipoproteins, artern wall,
and atherosclerosis - Plasma lipoprotein biosynthesis
(Rhesus monkeys)
P50HL-15062-07 0013 Study of lipoproteins, artery wall,
and atherosclerosis • Radioimmunoassay of apolipoproteins
(human, monkeys)
** R01HL15263-06 Lecithin-Cholesterol acetyltransferase
(human, rabbits)
P60HL-1 7269-04 0015 National heart and blood vessel
research and demonstration center - Lipoprotein
metabolism laboratory (human)
*♦ ROlHL-17597-05 Role of plasma lipoproteins in
atherosclerosis (swine, human)
** R01HL-19250-03 Mechanism of plasma cholesterol
esterification (human)
(contd)
■Excludes routine methodotojy OR covers only general projects which preclude indexing at the specitic level.
"Onented siinificanthr to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
MM
TRA
POlHL-22633-01 0002 Cellular and molecular biology of
lipoprotein metabolism • Sterol metabolism in tissue
culture cells
ROlHL-23945-06 Pathologic effects on cells of modified
lipoproteins (rats, human)
TRANSAMIDINASES
SEE AMIDINOTRANSFERASES
TRANSAXIAL TOMOGRAPHY
SEE RADIOGRAPHY, SCANNING, CAT*
TRANSCARBAMYLASES
R01HL18819-07 Chemical studies on sickle cell
hemoglobin (human)
TRANSCARBAMYLASES, ASPARTATE
TRANSCARBAMYIASE
R01HL-2I483-01 Electronic, thermodynamic and kinetics
of hemoglobin
TRANSCENDENTAL MEDITATION
SEE PSYCHIC ACTIVITY LEVEL. TROPHOTROPIC STATE,
MEDfTATION
TRANSCORTIN
SEE GLOBULINS, CORTICOSTEROID BINDING GLOBULIN
TRANSCRIPTION
SEE GENETICS, GENETIC REGUUTION, GENETIC INDUCTION-
REPRESSION-DEREPRESSION. TRANSCRIPTION
TRANSDUCING VIRUSES
SEE VIRUS CHARACTERISTICS. TRANSFORMING VIRUSES
TRANSDUCTION (GENETIC)
SEE GENETICS, SOMATIC CELL AND TRANSFORMATION,
TRANSDUCTION
TRANSEPITHELIAL SHUNT
SEE BIOLOGICAL TRANSPORT. MEMBRANE PERMEABILITY
AND TRANSPORT
TRANSFER (LEARNING)
SEE PSYCHOLOGY, LEARNING. TRANSFER
TRANSFER FACTOR (HYPERSENSITIVITY)
SEE HYPERSENSITIVITY. TRANSFER FACTOR
(HYPERSENSrriVITY)
TRANSFER RIBONUCLEIC ACID
SEE NUCLEIC ACIDS, TRNA
TRANSFERASES
SEE ALSO AMIDINOTRANSFERASES
SEE ALSO GLYCOSYLTRANSFERASES
SEE ALSO PHOSPHORYUSES
SEE ALSO PHOSPHOTRANSFERASES
SEE ALSO TRANSACYLASES
SEE ALSO TRANSCARBAMYUSES
P60HL1726904 0007 National heart and blood vessel
research and demonstration center ■ Correlative studies of
experimental myocardial ischemia (dog)
P60HL-1726904 0018 National heart and blood vessel
research and demonstration center ■ Mitochondria and
energetics (rabbits, dogs)
TRANSFERRIN
SEE METALLOPROTEINS. TRANSFERRIN
TRANSFORAAATION
SEE GENETICS, SOMATIC CELL AND TRANSFORMATION
SEE IMMUNITY. CELLUUR, LYMPHOCYTE ACTIVATION,
TRANSFORMATION AND PROLIFERATION
TRANSFORMATION NEOPLASTIC
SEE NEOPUSTIC TRANSFORMATION
TRANSFORMING VIRUSES
SEE VIRUS CHARACTERISTICS, TRANSFORMING VIRUSES
TRANSFUSION
SEE BLOOD TRANSFUSION
TRANSGLUTAMINASES
SEE AMINOACYLTRANSFERASES, TRANSGLUTAMINASES
TRANSGLYCOSIDASES
SEE GLYCOSYLTRANSFERASES
TRANSIENTS
SEE SOCIOENVIRONMENT. RESIDENTIAL MOBILITY, MIGRANTS
TRANSLATION
SEE GENETICS. GENETIC REGULATION, GENETIC INDUCTION-
REPRESSIONDEREPRESSION, TRANSLATION
TRANSMETHYLASES, CATECHOL O-METHYL
TRANSFERASE
ROlHL-12647-08 Inactivation of norepinephrine in vascular
tissue
ROlHL-1 748704 Adrenergic-vasoregulation interactions in
hypertension (human)
R01HL-2043902 Effects of insulin on neurovascular
transmission (human, rats, rabbits, hamsters)
ROlHL-22077-01 Vasoactive amine disposition in cultured
endothelium (rabbits)
516
TRANSMETHYLASES, N-METHYL TRANSFERASES
ROlHL-17487-04 Adrenergic-vasoregulation interactions in
hypertension (human)
ROlHL-17706-04 Psychosocial hypertension,
catecholamines and drugs (mice)
R01HL-19010-03 Metabolism and cell biology of lung
surfactant system (rabbits, sheep)
TRANSPLANTATION
SEE TISSUE COMPATIBILITY-TRANSPIANT. TRANSPUNTATION
TRANSPLANTATION ANTIGENS
SEE TISSUE COMPATIBILITY-TRANSPUNT, ISOALLOANTIGENS
TRANSPLANTATION AUTOLOGOUS
SEE TISSUE COMPATIBILITY-TRANSPLANT, TRANSPUNTATION
AUTOLOGOUS
TRANSPLANTATION HETEROLOGOUS
SEE TISSUE COMPATIBILITY-TRANSPLANT. TRANSPLANTATION
HETEROLOGOUS
TRANSPLANTATION HOMOLOGOUS
SEE TISSUE COMPATIBILITY-TRANSPUNT, TRANSPUNTATION
HOMOLOGOUS
TRANSPLANTATION IMMUNOLOGY
SEE TISSUE COMPATIBILITY-TRANSPUNT. ISOALLOIMMUNITY
TRANSPLANTATION REFERRAL CENTERS AND
REGISTRIES
SEE TISSUE COMPATIBILITY-TRANSPUNTATION RESOURCES,
REFERRAL CENTERS AND REGISTRIES
TRANSPLANTATION TYPING
SEE TISSUE COMPATIBILITY-TRANSPUNT.
HISTOCOMPATIBILITY TYPING
TRANSPORT
SEE BIOLOGICAL TRANSPORT, ION EXCHANGE AND
TRANSPORT
SEE BIOLOGICAL TRANSPORT, MEMBRANE PERMEABILITY
AND TRANSPORT
SEE KIDNEY FUNCTION, RENAL TUBUUR TRANSPORT
SEE RESPIRATORY GAS TRANSPORT
TRANSPORT DISORDERS, GASTROINTESTINAL
ABSORPTION
SEE GASTROINTESTINAL DISORDERS, MAUBSORPTION
SYNDROMES
TRANSPORT DISORDERS, INBORN (GENERAL)
SEE METABOLIC DISORDERS INBORN, TRANSPORT
DISORDERS
TRANSPORT FACILITATORS (STIMULANTS)
SEE BIOLOGICAL TRANSPORT, TRANSPORT EFFECTORS
TRANSPORT INHIBITORS
SEE BIOLOGICAL TRANSPORT, TRANSPORT EFFECTORS
TRANSPORT PROTEINS
SEE BIOLOGICAL TRANSPORT, TRANSPORT PROTEINS (SEE
ALSO SPECIFICS)
TRANSPOSITION OF GREAT VESSELS
SEE CONGENITAL ABNORMALITIES, CARDIOVASCUUR SHUNTS
ABNORMAL, VESSELS TRANSPOSITION
TRANSSULFURASES, COENZYME A
TRANSFERASES
ROlHL-13028-09 Regulation of myocardial fatty acid
metabolism (rats)
TRANSVERSE AXIAL TOMOGRAPHY
SEE RADIOGRAPHY, SCANNING, CAT*
TRASYLOL
SEE PROTEASES AND PEPTIDASES, TRASYLOL
TRAUMA
SEE INJURIES, TRAUMA
TREMATODE ANTIGENS
SEE IMMUNOLOGY, ANTIGENS HELMINTHIC
TREMOR
SEE NEUROMOTOR DISORDERS, TREMOR
TRIACYLGLYCEROL LIPASE
SEE LIPASES, TRIACYLGLYCEROL LIPASE
TRIAZINE NUCLEOSIDES, AZACYTIDINE
R01HL-20856-02 Platelet transfusions-Usage and
complications (human)
TRIBUTYRASE
SEE LIPASES, TRIACYLGLYCEROL LIPASE
TRICARBOXYLIC ACID CYCLE
SEE TRICARBOXYLIC ACIDS, KREBS CYCLE
TRICARBOXYLIC ACIDS
POlHL-1 1351-12 0015 Cellular and molecular
mechanisms of myocardial function - Effects of hypoxia
and ischemia on ion exchange and heart function (rabbits)
ROlHL-1 7403-03 Metabolic control of cardiac output
(dogs)
•Excludes routine methodology OR covers only general projects which preclude indexing
Oriented significanthf to above subject.
at the specific level.
M Grant has subprojects describing specific research aspects
See Appendix for investigator's name and grant number.
TRI
TRICARBOXYLIC ACIDS, CITRATES
P50HL-17667-04 0012 Study of ischemic heart disease -
Biochemistry of normal and ischemic heart-Glycolysis (rats)
R01HL-23159-01 Regulation of lipogenesis by
polyunsaturated fats (rats, chicks)
TRICARBOXYLIC ACIDS, KREBS CYCLE
ROlHL-13028-09 Regulation of myocardial fatty acid
metabolism (rats)
ROlHL-14461-08 Cardiac metabolisni in heart failure
(rats)
ROlHL-15622-05 Computer simulation in cardiology (rats,
dogs)
ROlHL-16768-04 The sympathetic nervous system and the
arterial wall (rabbits, pigeons)
P50HL-1 7665-04 0029 Study of ischemic heart disease -
Myocardial protein synthesis and degradation in low oxygen
states (rabbit, dog)
P50HL-1 7667-04 0012 Study of ischemic heart disease -
Biochemistry of normal and ischemic heart-Glycolysis (rats)
ROlHL-18143-03 Surgery and pulmonary tissue alterations
(dogs, rats, human)
R01HL-22I01-02 Hormone-substrate interaction in diabetic
myocyte (dogs, rats)
ROlHL-23161-01 0001 Biology of myocardial ischemia -
Mitochondrial lipid metabolism and cardiac ischemia (rat,
dog)
ROlHL-23240-01 Pulmonary vascular muscle metabolism
and contractility (rats, cattle)
TRICUSPID INSUFFICIENCY
SEE HEART DISORDERS, VALVUUR INSUFFICIENCY,
TRICUSPID INSUFFICIENCY
TRICUSPID VALVE
SEE HEART, VALVES, TRICUSPID VALVE
TRIGEMINAL NERVE
SEE NERVOUS SYSTEM, CRANIAL NERVES, TRIGEMINAL
NERVE
TRIGEMINAL NUCLEUS (SPINAL)
SEE BRAIN, PONS, TRIGEMINAL NUCLEUS (SPINAL)
TRIGLYCERIDES
SEE LIPIDS, GLYCERIDES, TRIGLYCERIDES
TRIIODOTHYRONINE
SEE THYRONINE, TRIIODOTHYRONINE
TRIMETHAPHAN CAMPHORSULFONATE
SEE SULFONATES, TRIMETHAPHAN CAMSYUTE
TRIMETHAPHAN CAMSYLATE
SEE SULFONATES, TRIMETHAPHAN CAMSYUTE
3,4,5-TRIMETHOXYBENZOYL METHYL RESERPATE
SEE ALKALOIDS, RAUWOLFIA TYPE, RESERPINE
TRIOSE ACIDS, GLYCERIC ACID DIPHOSPHATES
SEE ALSO PHOSPHOMUTASES, PHOSPHOGLYCEROMUTASE
R01HL-05791-18 Structure and function In hemoglobins
(human)
R01HL-06950-17
vertebrates)
ROlHL-07449-17
(human)
POlHL-08899-14 0010
health and disease
(human)
ROlHL-11154-12 Blood group antigens and antibodies
(human)
ROlHL-12174-11 Ventilation/pertusion distribution in the
lung (human, mammals)
ROlHL-12256-15 Polymerization of sickle-cell hemoglobin
(human)
R01HL-13567-06 Ion transport across cell membranes
(human)
POlHL-14414-07 0014 Environmental influences on
cardiorespiratory and cellular functions - Temperature and
acid-base status in tissues, cells, and subcellular system
POlHL-15194-07 0006 Pathophysiology of
cardiopulmonary dysfunction - Kinetics of gas exchange-
Velocity of Bohr effect in erythrocytes (human)
P60HL-15999-05 0021 Miami comprehensive sickle cell
center - Diphosphonates-Erythrocyfe calcium loading,
maturation (human, chick embryo)
P60HL-16008-06 0016 Wayne State University
comprehensive sickle cell center - Red blood cell glycolysis
in sickle cell patients
ROIHL- 1642 1-08 Determinants of RBC deformabiljty and
capillaiv flow (human, mice)
R01HL-16647-05 Studies on the control of sickle cell crisis
(human)
POlHL-16833-04 0001 Hemoglobin and red cell system in
hemoglobinopathies - Motility, association and ligand
binding in hemoglobin -Hydrogen exchange
POlHL-16833-04 C003 Hemoglobin and red cell system in
hemoglobinopathies - Oxygen binding curves and equilibria
(human)
ROlHL-17808-03 Effect of altered oxygen affinity on
oxygen transport (human, rats)
ROlHL-18082-03 Erythrocyte phosphates and vertebrate
gas transport (amphibians, reptiles)
(contd)
Red cell metabolism (human.
Formation and survival of red blood cells
Tolerance to respiratory gases in
High oxygen pressure in septic shock
TRI
ROIHI 18328 03 H«mo|lobin function ind tlisut
oxyienition (humani do|s)
ROIHI 1898*01 PSO «M«ct on worciM limit In st*bl«
an|lna (human)
ROIHL 19324 02 Mechanisms of the Inhibition of siciiling
by DBA (human)
ROIHL 19488-03 Picosecond laser studies ot heme
proteins
ROIHL 20074 02 Structure and function of amidinated
human hemo|lobin
POIHL 21016 02 0005 Sickle cell anemia and other
hemoglobinopathies Lijand liinetics in normal and Hb S
containing erythrocirtes (human)
POIHL2101602 0006 Sickle cell anemia and other
hemoglobinopathies Analysis of the o«ygen dissociation
curve ot Hb S containing red cells
PO1HL2101602 0011 Sickle cell anemia and other
hemoglobinopathies Metabolic effects of anti sickling
agents (hamsters)
POIHL 21016 02 0014 Sickle cell anemia and other
hemoglobinopathies Human hemoglobin mutants with
abnormal oxygen binding
TRIOSE ALCOHOLS, GLYCERIN
SEE ALSO LIPIDS. GLYCERIDES
SEE ALSO LIPIDS. GLYCERYL ETHERS
P01HL0631217 0033 Surgical cardiology • Studies In
cryopreservations (rats)
ROIHL 1527306 Metabolism of pulmonary surfactant
(human, rats)
R01HL1946302 Pathophysiology ot acute renal failure
(rats)
ROIHL 1972203 Aerosol growth in the respiratory system
(models)
ROlHL-20219-02 Ciyopreservation of the isolated heart
(rats)
TRIOSE ALCOHOLS, GLYCEROPHOSPHATES
SEE ALSO OXIDOREDUCTASES. GLYCEROPHOSPHATE
DEHYDROGENASE
P01HL0630818 0040 Mechanisms and therapy of
circulatory disease ■ Metabolism and fatty acid utilization-
Heart electrical stability (rats, dogs)
P60HL1506107 0002 Response of lung to injury ■
Oxidative metabolism, phospholipid synthesis, and response
to toxins (rats)
ROlHL-19010-03 Metabolism and cell biology of lung
surfactant system (rabbits, sheep)
POlHL-2099302 0006 Population dynamics of arterial
cells in atherogenesis - Mechanism of regression of
atherosclerosis by diet and injury (swine)
TRIOSE ALCOHOLS, NITROGLYCERIN
M POlHL-04664-18 Cardiovascular and lung dynamics
POlHL-0466418 0010 Cardiovascular and lung dynamics
- Left ventricular dynamics (human)
POlHL-04664-18 0011 Cardiovascular and lung dynamics
■ Detection of abnormal segments of the human ventricle
by measure of asynergy
POlHL-0466418 0012 Cardiovascular and lung dynamics
■ Quantitative single plane left ventricular angiography
(human)
** POlHL-04664-18 0013 Cardiovascular and lung dynamics
■ Ventricular function in coronary disease using NTG and
ventriculograms (human)
P01HL04664-18 0014 Cardiovascular and lung dynamics
■ Clinical application of computer analysis of ventricular
wall motion
POlHL-06308-18 0011 Mechanisms and therapy of
circulatory disease ■ Blood flow and electrical dysfunction
in ventricular arrhythmia (human)
POlHL-06308-18 0038 Mechanisms and therapy of
circulatory disease - Electrophysiology of ventricuair
arrhythmias associated with ischemia (dogs)
POlHL-06664-17 0034 Cardiopulmonary function in
remediable vascular disease • Role of hyperosmolar agents
in ischemic heart disease (dogs)
ROlHL-07139-17 Cardiodynamics and metabolism of
congestive failure (human, dogs)
R01HL0831114 Effects of drugs upon myocardial hypoxia
(dogs, turtles)
R01HL10009-13 Regional lung function in man
ROlHL-12322-10 Extrinsic factors influencing myocardial
performance (dogs, swine)
P01HL-14388-07 0185 Regulation of the circulation in
pathological states • Reflex control of venous tone (human,
rabbits, dogs)
POlHL-14388-07 0230 Regulation of the circulation in
pathological states ■ Effects of indomethacin in patients
with carcinoid syndrome
ROlHL-14571-05 Myocardial preservation and coronary
reperfusion (baboons, dogs)
R01HL15416-06 Cardiovascular control In normal and
disease states (dogs, baboons)
ROlHL-16066-05 Studies on neurogenic control of the
circulation (human, dogs)
R01HL16236-04 Detailed characteristics of coronary blood
flow (horses, dogs, calves)
ROlHL-1641204 Release of nucleosides from the ischemic
heart (human, dogs)
*• P50HL-17655-04 0001 Study of ischemic heart disease ■
Intravenous nitroglycerin-Ventricular function and infarct
size (human, dog)
517
P50HL 17655 04 0009 Study of Ischemic heart disease
Random trial ot medical and surgical therapy In unstable
angina (human)
P50HL 17655 04 0014 Study of ischemic heart diseiM ■
Blood flow and gas tension in myocardial ischemia and
infarction (dog. monkey)
P50HL 17669 04 0012 Ischemic heart disease center
(SCOR) Circulatory assistance (human, dog)
P50HL 176 70 04 0009 Study ot ischemic heart disease
Surgical treatment of localized left ventricular dyssynergy
(human, dogs)
ROIHL 1802403 Regional myocardial flow and function
relationships (dogs)
ROIHL 1820403 Regional blood flow in viral myocarditis
(turkeys)
ROIHL 1846803 The distribution of flow in the
myocardium (dog. pig)
ROIHL- 1853704 Regional blood flow after acute
myocardial injury (dogs)
ROIHL 19202 03 Adenosine, prostaglandins In relation to
coronary flow (guinea pigs)
ROlHL-19451-03 0001 Functional characteristics of the
left heart Ventricular performance using epicardial
radiopaque markers (human)
ROIHL 19451-03 0003 Functional characteristics of the
left heart - Left ventricular segmental contraction (human,
dogs)
ROIHL 1945103 0004 Functional characteristics of the
left heart - Quantitative coronary arteriography (human)
ROlHL-1993702 Vasodilators in experimental myocardial
infarction (dogs)
ROlHL-20598-03 The coronary vascular response to
ischemia (dogs, pigs)
ROlHL-20630-03 Development of a pulsed Ooppler velocity
detector (human, animals)
R23HL-2115102 Ischemic myocardium-Delivery of blood
flow and drugs (dogs)
ROlHL-2 1684-02 0005 Radionuclide infarct sizing and
therapy evaluation - Clinical evaluation of radioisotope
imaging methods for quantifying infarct size
** ROIHL-2227301 Oral and lung absorption of nitroglycerin
(rats)
TRIOSE PHOSPHATE DEHYDROGENASE
SEE OXIDOREDUCTASES, GLYCERALDEHYDE PHOSPHATE
DEHYDROGENASE
TRIOSE PHOSPHATES
SEE TRIOSES, TRIOSE PHOSPHATES
TRIOSES, GLYCERALDEHYDE
** R01HL188 19-07 Chemical studies on sickle cell
hemoglobin (human)
TRIOSES, TRIOSE PHOSPHATES
ROIHL- 150 13-07 Lung oxidative metabolism and energy
production (rodents, rabbits)
TRIPHENYLS, HALOGENATED
SEE HALOBENZENES, HALOGENATED BIPHENYLS-TRIPHENYLS
AND ANALOGS
TRIPLETS
SEE FAMILY, TWINS AND MULTIPLETS
TRISOMY
SEE GENETICS, MUTATION, GENOME MUTATION, TRISOMY
TRITIUM
SEE HYDROGEN, TRITIUM*
TRNA
SEE NUCLEIC ACIDS. TRNA
TROPANES, ATROPINE
ROlHL-03941-18 Uterine blood flow and changes in
pregnancy (sheep)
ROlHL-04457-20 Cellular aspects of active transport (fish,
rabbits, anurans, turtles)
POlHL-11310-12 0079 Mechanisms of cardiovascular
disease - Electrophysiological studies of complete heart
block (human)
ROlHL-11907-08 Mechanisms of physiological responses
to exercise (human, dogs)
POlHL-12738-10 0035 Physiologic pharmacology and its
clinical applications - Function and dysfunction of the
sinoatrial node (human)
POlHL-13 10809 0017 Clinical heart transplantation -
Electrophysiology of the transplanted denervated human
heart
POlHL-1438807 0209 Regulation of the circulation in
pathological states - Neural regulation of vascular
resistance in human hypertension
ROlHL-147 13-06 Hypothermia and the heart (bats, guinea
pigs)
ROlHL-1575806 Catecholamine release in the heart
(dogs)
ROlHL-16066-05 Studies on neurogenic control of the
circulation (human, dogs)
ROlHL-16463-05 Localization of airways obstruction and
responses
ROlHL-16656-06 Left ventricular function in exercise
(dogs)
R01HL17873-04 Pathophysiology of exercise-induced
asthma (human)
TYP
ROIHL 18467 03 fingertip blood flow in noimalt and
Raynaud's disease (human)
P50HI 19170-02 0007 Harvard pulmonary SCOR -Chto«ic
diseases of the airways Therapy effect on airway
obstruction in acute asthma (human)
ROIHL 20572 02 0007 Hemodynamic relali«M to
metabolism in hypertension Drug effects on cardiac
function and hypertropy (rats)
POIHL 21584 02 0005 Respiratory methanics in B«»r»al
and abnormal states Regulation and behavior of airway
smooth muscle (human, animals)
ROIHL 22546-02 Baroreceptoc reflex mechanisi»i in IBM
TROPANES, COCAINE
ROIHL 08359- 14 Morphopharmacotogy of vascular
adrenergic transmission (rabbits, rats)
ROIHL 15758-06 Catecholamine release m the heart
(dogs)
P01HL18575-03 0001 Mechanisms of vascular changes
in hypertension - Arteries and resistance vessels in
hypertension (pigs, rats)
POIHL 20581 01 0001 Vascular neuroeffectOf
mechanisms in health and disease Vascular neuroeflectof
mechanism (rabbits)
TROPHOTROPIC STATE
SEE PSYCHIC ACTIVITY LEVEL, TROPHOTROPtC STATE
TROPOCOLLAGEN
SEE ALBUMINOIDS, COLLAGEN, TROPOCOLUGEH
TROPOMYOSIN
SEE MUSCLE PROTEINS (AND CONTRACTIli PROTEINS).
TROPOMYOSIN
TROPONIN
SEE MUSCLE PROTEINS (AND CONTRACTILE PROTEINS),
TROPONIN
TRYPANOSOMA CRUZI
SEE PROTOZOA, MASTIGOPHORA, TRYPANOSOMA CRUZI
TRYPSIN
SEE PROTEASES AND PEPTIDASES, TRYPSIN
TRYPSIN INHIBITORS
SEE ENZYME INHIBITORS, TRYPSIN INHIBITORS
TRYPTOPHAN
SEE CYCLIC AMINO ACIDS, TRYPTOPHAN
TRYPTOPHAN 2,3-DIOXYOENASE
SEE OXYGENASES, TRYPTOPHAN 2,3-DIOXYGENASE
TRYPTOPHAN 5-HYDROXYlASE
SEE OXYGENASES, TRYPTOPHAN 5-MONOOXYGENASE
TRYPTOPHAN 5-MONOOXYOENASE
SEE OXYGENASES, TRYPTOPHAN 5-MONOOXYGENASE
TRYPTOPHAN OXYGENASE
SEE OXYGENASES, TRYPTOPHAN 2,3-DIOXYGENASE
TRYPTOPHAN PYRROLASE
SEE OXYGENASES. TRYPTOPHAN 2,3-OIOXYGENASE
TUBERCULIN TYPE HYPERSENSITIVITY
SEE HYPERSENSITIVITY, DELAYED HYPERSENSITIVITY
TUBERCULOSIS
SEE BACTERIAL DISEASES, ACTINOMYCETAIES INfECTIOHS.
TUBERCULOSIS
TUMOR ANGIOGENESIS FACTOR
SEE NEOPUSMS VASCULAR SUPPLY, TUMOR ANGIOGENESIS
FACTOR
TUMOR ANTIBODIES
SEE NEOPLASMS IMMUNOLOGY, TUMOR ANTIBODIES
TUMOR ANTIGENS
SEE NEOPLASMS IMMUNOLOGY, TUMOR ANTIGENS
TUMOR CELLS
SEE NEOPLASTIC CELLS
TUMORS
SEE NEOPLASMS
TURTLES
SEE REPTILES, TURTLES*
TWINS AND MULTIPLETS
SEE FAMILY, TWINS AND MULTIPLETS
TYPING
SEE BLOOD GROUPS
SEE BLOOD PLATELET TYPING
SEE CELL TYPES
SEE TISSUE COMPATIBILITY-TRANSPLANT,
HISTOCOMPATIBILITY TYPING
TYPING, MICROBIAL (GENERAL)
SEE MICROBIAL IDENTIFICATION AND CLASSIFICATION
(TECHNIQUES)
TYPING REFERRAL CENTERS,
HISTOCOMPATIBILITY
SEE TISSUE COMPATIBILITY-TRANSPLANTATION RESOURCES,
REFERRAL CENTERS AND REGISTRIES
(contd)
•Excludes routine methodotogy OR covers only general projects which preclude indexing at the specific level.
"Onented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
TYP
TYPING SERA FOR HISTOCOMPATIBILITY TYPING
SEE TISSUE COMPATIBIUTY-TRANSPLAM.
HISTOCOMPATIBILITY TYPING
TYPING TAXONOMICAL
SEE BIOLOGY, SYSTEMATIC
TYPING TAXONOMICAL, MICROBIAL (GENERAL)
SEE MICROBIAL IDENTIFICATION AND CLASSIFICATION
(TECHNIQUES)
TYRAMINASE
SEE OXIDOREDUCTASES, AMINE OXIDASE (FUVIN
CONTAINING)
TYRAMINE
SEE PHENOLIC AMINES, TYRAMINE
TYRAMINE OXIDASE
SEE OXIDOREDUCTASES, AMINE OXIDASE (FUVIN
CONTAINING)
TYROSINASE
SEE OXYGENASES, MONOPHENOL MONOOXYGENASE
TYROSINE
SEE CYCLIC AMINO ACIDS, TYROSINE
TYROSINE 3-HYDROXYLASE
SEE OXYGENASES. TYROSINE 3-MONOOXYGENASE
TYROSINE 3-MONOOXYGENASE
SEE OXYGENASES, TYROSINE 3-MONOOXYGENASE
UDDER
SEE REPRODUCTIVE SYSTEM FEMALE. MAMMARY GUNDS -
UDP GLUCOSE:ALPHA.l,4-GLUCAN ALPHA-4.
GLUCOSYLTRANSFERASE
SEE GLYCOSYLTRANSFERASES, UDP GLUCOSE ALPHA! 4-
GLUCAN ALPHA-4GLUC0SYLTRANSFERASE
ULCER
SEE CARDIOVASCULAR DISORDERS, VARICOSE ULCER
SEE GASTROINTESTINAL DISORDERS, PEPTIC ULCER
SEE SKIN ULCERS
ULCERATIVE COLITIS
SEE GASTROINTESTINAL DISORDERS. ENTERITIS. ULCERATIVE
COLITIS
ULTRACENTRIFUGATION
SEE PHYSICAL SEPARATION. ULTRACENTRIFUGATION*
ULTRASONIC CARDIOGRAPHY
SEE HEART VISUALIZATION. ECHOCARDIOGRAPHY*
ULTRASONIC (ECHO) ANGIOCARDIOGRAPHY
SEE HEART VISUALIZATION.
ANGIOCARDIOULTRASONOGRAPHY*
ULTRASONIC ECHOENCEPHALOGRAPHY
SEE BRAIN VISUALIZATION, ULTRASONIC
ECHOENCEPHALOGRAPHY*
ULTRASONIC FLOWMETER
SEE CARDIOVASCULAR DISORDERS DIAGNOSIS, BLOOD FLOW
MEASUREMENTS, ULTRASONIC*
SEE RESPIRATORY DISORDERS DIAGNOSIS, RESPIRATORY
AIRFLOW MEASUREMENTS, ULTRASONIC*
ULTRASONIC GAS FLOWMETERS, RESPIRATORY
SEE RESPIRATORY DISORDERS DIAGNOSIS, RESPIRATORY
AIRFLOW MEASUREMENTS, ULTRASONIC*
ULTRASONIC HOLOGRAPHY
SEE OPTICS, PHOTOGRAPHY, HOLOGRAPHY, ACOUSTIC*
ULTRASONIC MICROSCOPY
SEE OPTICS, MICROSCOPY, ULTRASONIC*
ULTRASONIC SCANNING
SEE PHYSICAL PROPERTIES, SOUND. ULTRASONIC
SCANNING*
ULTRASONICS
SEE PHYSICAL PROPERTIES. SOUND. ULTRASONICS
ULTRASONOGRAPHY
SEE PHYSICAL PROPERTIES. SOUND. ULTRASONOGRAPHY
ULTRASOUND ADVERSE EFFECTS
SEE PHYSICAL PROPERTIES. SOUND, ULTRASOUND ADVERSE
EFFECTS
ULTRASOUND SCANNING
SEE PHYSICAL PROPERTIES, SOUND. ULTRASONIC
SCANNING*
UMBILICAL CORD
SEE PREGNANCY, UMBILICAL CORD
UNCONSCIOUSNESS
SEE NEUROLOGIC MANIFESTATIONS, UNCONSCIOUSNESS
UNITED STATES
SEE GEOGRAPHICAL SITES, UNITED STATES
UNIVERSITIES
SEE EDUCATION, UNIVERSITIES
•^SlU^Ti'lf "1!!!^'"°^°'' ""'" ""'> «•"«"' "">'«<' "Wch preclude indeimg
Onented significantly to above subject.
518
UNNATURAL PEPTIDES
SEE PEPTIDES, UNNATURAL PEPTIDES
UNSATURATED FATS
SEE LIPIDS, FATS, UNSATURATED FATS
UNSATURATED FATTY ACIDS
SEE FATTY ACIDS, UNSATURATED FATTY ACIDS
URACIL-4-CARBOXYLIC ACID
SEE PYRIMIDINES, OROTIC ACID
URANIUM
SEE RADIOISOTOPES, ACTINIDE SERIES, URANIUM
URBAN AREAS
SEE SOCIOENVIRONMENT. URBAN AREAS
URBAN POVERTY AREAS
SEE SOCIOENVIRONMENT. URBAN POVERTY AREAS
UREA
SEE AMIDES. UREA
UREA CYCLE
SEE AMINO ACIDS. UREA CYCLE
UREMIA
SEE KIDNEY DISORDERS. UREMIA
URETER OBSTRUCTION
SEE URINARY TRACT DISORDERS, URETER OBSTRUCTION
URETHAN
SEE CARBAMATES, URETHAN
URETHANE POLYMERS
SEE PLASTICS. POLYURETHANES
URETHRITIS
SEE URINARY TRACT DISORDERS, URETHRITIS
URIC ACID
SEE PURINES. URIC ACID
URICOSURIC AGENTS
SEE PURINESPYRIMIDINES METABOLISM ERRORS, GOUT
DRUGS
URIDINE
SEE PYRIMIDINE NUCLEOSIDES. URACIL NUCLEOSIDES
URIDINE
URIDINE DIPHOSPHATE
SEE PYRIMIDINE NUCLEOTIDES. URACIL NUCLEOTIDES
URIDINE DIPHOSPHATE
URINALYSIS (CHEMICAL ANALYSIS)
SEE CHEMISTRY. CLINICAL, URINE CHEMICAL ANALYSIS
URINARY ACIDITY
SEE URINE ACIDITY
URINARY BLADDER
SEE URINARY TRACT, URINARY BLADDER
URINARY BLADDER DISORDERS
SEE URINARY TRACT DISORDERS, URINARY BUDDER
DISORDERS
URINARY TRACT, URINARY BLADDER
SEE ALSO URINARY TRACT DISORDERS, URINARY BLADDER
DISORDERS
** POlHL-1438807 0191 Regulation of the circulation in
pathological states ■ Regulation of chloride transport in
epithelial membranes (turtles)
ROlHL-21849-02 Control of sodium transport and cellular
respiration (toad bladder)
URINARY TRACT DISORDERS, URETER
OBSTRUCTION
R01HL-17781-03 Hypertension, kidney disease and renal
lymph (dogs, rats)
URINARY TRACT DISORDERS, URETHRITIS
P01HL08214-15 0023 Chemical and biological properties
of lipids ■ Lipids in microorganisms and cell cultures
(hamsters, mosquitoes)
URINARY TRACT DISORDERS, URINARY
BLADDER DISORDERS
P01HL14388-07 0191 Regulation of the circulation in
pathological states - Regulation of chloride transport in
epithelial membranes (turtles)
URINARY TRACT SURGERY
SEE ALSO KIDNEY SURGERY
R01HL-13754-08 Postoperative thromboembolism in
surgical patients (human)
URINE*
SEE ALSO METABOLIC DISORDERS INBORN,
AMINOACIDOPATHIES
SEE ALSO PROTEINURIA
N01HB-82926-00 Source of human urinary erythropoietin
R01HL19066-03 Synthesis and evaluation of
prostaglandin metabolites (guinea pigs)
R23HL-19601-01 Cardiac response to chronic metabolic
acidosis (rats)
at the specific level.
M Grant has subprajects describing specific research aspects
See Appendix for investigators name and grant number
VAR
R23HL-2 1 083-02 Pharmacokinetics of digoxln and digitoxin
in humans (rats)
NOlHR-72922 01 Cystic fribrosis factor identication and
quantification (human)
URINE ACIDITY
P01HLC6285-18 0198 Cardiovascular-respiratory
physiology and biochemistry - Renal tubular secretion of
hydrogen ion (animals)
R01HL-14720-08 Factors governing the renal excretion of
acid (humans, rats)
URINE CHEMICAL ANALYSIS
SEE CHEMISTRY. CLINICAL. URINE CHEMICAL ANALYSIS
UROGENITAL SYSTEM
SEE REPRODUCTIVE SYSTEM (GENERAL)
UROKINASE
SEE BLOOD COAGUUTION. UROKINASE
URONIC ACIDS
SEE SUGAR ACIDS. URONIC ACIDS
URUSHIOL OXIDASE
SEE OXYGENASES. MONOPHENOL MONOOXYGENASE
USER PRODUCTS
SEE CONSUMER PRODUCTS
UTERINE DISORDERS
SEE REPRODUCTIVE SYSTEM DISORDERS FEMALE, UTERINE
DISORDERS
UTERUS
SEE REPRODUCTIVE SYSTEM FEMALE. UTERUS
UTILIZATION OF HEALTH SERVICES-RESOURCES
SEE HEALTH CARE (SERVICES)(RESOURCES) UTILIZATION
UTILIZATION REVIEW
SEE HEALTH CARE QUALITY
VACCINES, BACTERIAL (GENERAL)
R23HL-21212-02 Alveolar macrophage function in
Pseudomonas infection (dgs)
R23HL-21997-01 Pulmonary immunopathology in the
compromised host (guinea pigs)
VACCINES, BACTERIAL, PNEUMOCOCCAL
VACCINE
P60HL-15I62-07 0021 Comprehensive sickle cell center -
Pneumococcal vaccine in sickle cell disease (children)
P60HL- 16008-06 0019 Wayne State University
comprehensive sickle cell center - Cell mediated immunity
in sickle cell anemia (human)
•* P60HL-20985-01 0002 Northern California sickle cell
center - Immunization with polyvalent pneumococcal
polysaccharide vaccine (human)
VACCINES, VIRAL VACCINES (GENERAL)
POlHL-06314-17 0061 Immunologic mechanisms in
cardiovascular disease - Role of viruses in cardiovascular
and renal disease (human, mice)
R01HL-I9651-03 Host factors in pathogenesis of
respiratory disease (human, hamsters)
VACCINES, VIRAL, HEPATITIS, SERUM
** POlHL-09011 15 0020 A research and resource program
in blood - Passive immunization in the prevention of
transmission of hepatitis B (human)
** POlHL-09011-15 0023 A research and resource program
in blood - Evaluation of hepatitis B vaccine in endemic
settings (human)
VACUOLES
SEE CELL COMPONENTS. VACUOLES
VAGOTOMY
SEE NEUROSURGERY. VAGOTOMY
VAGUS NERVE
SEE NERVOUS SYSTEM, CRANIAL NERVES, VAGUS
VALINE
SEE AMINO ACIDS, VALINE
VALINOMYCIN
SEE ANTIBIOTICS, VALINOMYCIN
VALSALVA'S MANEUVER
SEE RESPIRATORY FUNCTION, VALSALVA'S MANEUVER
VALVES, HEART
SEE HEART, VALVES
VALVULAR HEART DISORDERS
SEE HEART DISORDERS, VALVUUR
VALVULAR INSUFFICIENCY
SEE HEART DISORDERS, VALVUUR INSUFFICIENCY
VAN DER WAAL'S FORCES
SEE MOLECUUR INTERACTIONS NONBONDING
VANCOMYCIN
SEE ANTIBIOTICS, VANCOMYCIN
VAPORS
SEE PHYSICAL PROPERTIES, FLUID STATE, VAPORS
(contd)
VAR
VARICES
SEE CARDIOVASCULAR DISORDERS, VASODIIATATION
SEE GASTROINUSIINAl CIRCUUTORY DISORDERS,
ESOPHAGEAL VARICES
VARICOSE ULCER
SEE CARDIOVASCULAR DISORDERS, VARICOSE ULCER
VAS DEFERENS
SEE REPRODUCTIVE SYSTEM MALE. EPIDIDYMIS AND DUCTS
VASA VASORUM
SEE CARDIOVASCULAR SYSTEM, VASA VASORUM
VASCULAR BEDS
SEE CARDIOVASCULAR SYSTEM, CAPILLARY BEOS
VASCULAR DISORDERS (GENERAL)
SEE CARDIOVASCUUR DISORDERS, VASCUUR DISORDERS
(GENERAL)
VASCULAR HEMOPHILIA
SEE BLOOD COAGULATION DISORDERS, VON WILLEBRAND'S
DISEASE
VASCULAR OCCLUSION (PARTIAL OR TOTAL),
THERAPEUTIC
SEE CARDIOVASCULAR SURGERY, VASCULAR OCCLUSION
THERAPEUTIC
VASCULAR PERMEABILITY
SEE CARDIOVASCULAR SYSTEM, ENDOTHELIUM
PERMEABILITY
VASCULAR RESISTANCE
SEE CARDIOVASCULAR FUNCTION, VASCULAR RESISTANCE
VASCULAR SUPPLY OF NEOPLASMS
SEE NEOPUSMS VASCULAR SUPPLY
VASOACTIVE AGENTS (GENERAL)
SEE CARDIOVASCUUR AGENTS, VASOACTIVE AGENTS
(GENERAL)
VASOACTIVE PEPTIDES, PRECURSORS, AND
RELATED ENZYMES
SEE PEPTIDES, VASOACTIVE PEPTIDES
VASODILATATION
SEE CARDIOVASCULAR DISORDERS, VASODIUTATION
VASODILATORS
SEE CARDIOVASCULAR AGENTS, VASODILATORS
VASODILATORS, CORONARY
SEE CARDIOVASCUUR AGENTS, VASODIUTORS, CORONARY
VASOMOTION
SEE CARDIOVASCUUR FUNCTION. VASOMOTION
VASO-OCCLUSIVE CRISIS IN SICKLE CELL
DISEASES
SEE HEMOPROTEINS, HEMOGLOBINOPATHIES. SICKLE CELL
CRISIS
VASOPRESSIN
SEE PITUITARY-DIENCEPHALON HORMONES, VASOPRESSIN
VASOPRESSIN DEFECTIVE DIABETES INSIPIDUS
SEE METABOLIC DISORDERS (INBORN), DIABETES INSIPIDUS
VASOPRESSIN DEFICIENCY
SEE METABOLIC DISORDERS (INBORN), DIABETES INSIPIDUS
VASOPRESSORS
SEE CARDIOVASCUUR AGENTS, VASOPRESSORS
VASOSPASMS
SEE CARDIOVASCUUR DISORDERS, VASOSPASM
VECTORCARDIOGRAPHY
SEE HEART DISORDERS DIAGNOSIS, VECTORCARDIOGRAPHY*
VECTOR MAGNETOCARDIOGRAPHY
SEE HEART DISORDERS DIAGNOSIS. VECTOR
MAGNETOCARDIOGRAPHY*
VEGETABLES OILS (FATS)
SEE LIPIDS. OILS, VEGCTABLE OILS
VEGETARIANISM
SEE NUTRITION, DIET, VEGETARIANISM
VEHICLES DRUG
SEE DRUGS VEHICLES
VEINS
SEE CARDIOVASCUUR SYSTEM, VEINS
VENA CAVA FILTERS
SEE BLOOD TREATMENT, BLOOD FILTERS, VENA CAVA
FILTERS
VENA CAVAE
SEE CARDIOVASCUUR SYSTEM, VEINS, VENA CAVAE
VENOGRAPHY (GENERAL)
SEE CARDIOVASCUUR VISUALIZATION, VENOGRAPHY
(GENERAL)*
S19
VENOMS
SEE TOXICOLOGY. ANIMAL POISONS. VENOMS
VENOUS BYPASS OF LIVER
SEE LIVER CIRCUUIION, VENOUS BYPASS Of LIVER
VENOUS INFUSIONS
SEE DOSAGE AND ROUTE, INFUSIONS VENOUS
VENOUS OCCLUSIONS
SEE CARDIOVASCULAR DISORDERS. VENOUS OCCLUSIONS
VENOUS SINUSES, INTRACRANIAL
SEE CEREBROVASCUUR SYSTEM. VENOUS SINUSES
INTRACRANIAL
VENOUS THROMBOSIS
SEE CARDIOVASCUUR DISORDERS. THROMBOSIS. VENOUS
VENTILATION, HEATING, AIR CONDITIONING
SEE ENVIRONMENT CONTROLLED
VENTRAL SENSORY NUCLEUS
SEE BRAIN. MEDULU OBLONGATA. SOLITARY TRACT
NUCLEUS
VENTRICLES
SEE BRAIN. CENTRAL SPACES
SEE HEART. VENTRICLES
VENTRICULAR FIBRILLATION
SEE HEART DISORDERS. ARRHYTHMIA, VENTRICUUR
FIBRILUTION
VENTRICULAR HYPERTROPHY
SEE HEART DISORDERS. HEART ENURGEMENT,
VENTRICUUR HYPERTROPHY
VERAPAMIL
SEE PHENYULKYUMINES, VERAPAMIL
VERTEBRAL INJURIES
SEE INJURIES. BACK. SPINAL
VERTEBRATES
SEE ANIMALS. CHORDATES. VERTEBRATES*
VERY LOW DENSITY LIPOPROTEINS
SEE LIPOPROTEINS BLOOD. VLDL
VESTIBULAR APPARATUS
SEE EAR. UBYRINTH. VESTIBULAR APPARATUS
VESTIBULAR PATHWAYS
SEE EAR. UBYRINTH, VESTIBULAR APPARATUS
VESTIBULAR REFLEX
SEE EAR, UBYRINTH, VESTIBULAR REFLEX
VETERINARY MEDICINE
SEE ANIMALS. VETERINARY MEDICINE
VETERINARY SCIENCE
SEE ANIMALS, VETERINARY SCIENCE
VIBRATIONS, CHEMICAL BONDS
SEE CHEMICAL BONDS, VIBRATIONS
VILLI, INTESTINAL
SEE GASTROINTESTINAL SYSTEM, INTESTINES. MUCOSA. VILLI
VINBLASTINE
SEE ALKALOIDS, VINBUSTINE
VINCA ALKALOIDS
SEE ALKALOIDS, VINCA
VINCALEUKOBLASTINE
SEE ALKALOIDS, VINBUSTINE
VINYLBENZENE POLYMERS
SEE RUSTICS. STYRENE POLYMERS
VINYL CHLORIDE
SEE HALOOLEFINS, VINYLEDENE CHLORIDE
VINYL CHLORIDE POLYMERS
SEE RUSTICS. POLYVINYLS
VINYLEDENE CHLORIDE
SEE HALOOLEFINS, VINYLEDENE CHLORIDE
VINYL POLYMERS
SEE RUSTICS. POLYVINYLS
VIOKASE
SEE PANCREAS. PANCREATIC ENZYMES
VIOLENCE
SEE PSYCHOLOGY, BEHAVIOR, AGGRESSION
VIRAL ANTIBODIES
SEE IMMUNOLOGY, ANTIBODIES VIRAL
VIRAL ANTIGENS
SEE IMMUNOLOGY, ANTIGENS VIRAL
VIRAL PROTEINS
SEE PROTEINS. VIRAL (GENERAL)
VIRAL RNA
SEE NUCLEIC ACIDS. RNA VIRAL
VIR
VIRAL TYPING AND IDENTIFICATION
Sff MICROBIAL IDfNIIFICAIION AND CLASSIflCAIION. VIRAL
TYPING AND IDENIIf ICAIION
VIRAL VACCINES
SEE VACCINES. VIRAl VACCINES (GENERAL)
VIRICIDES
SEE COMMUNICABLE DISEASE CONTROL AGENTS. ANTIVIRAL
VIROLOGY (EXPERIMENTAL) STUDY SECTION
SEE EXPERIMENTAL VIROLOGY STUDY SECTION
VIROLOGY STUDY SECTION
*• ROIHL 1740405 Immunolosic mechanisms in heart
disease (mice)
•• ROIHL 1853503 Epidemiology and course o( vital
myopeiicarditis (human)
VIRULENCE MICROORGANISMS
SEE MICROORGANISMS VIRULENCE
VIRUS CHARACTERISTICS, TRANSFORMING
VIRUSES
SEE ALSO GENETICS. SOMATIC CELL AND TRANSFORMATION
POIHL 09011 15 0010 A research and resource program
in blood Chromosome changes in human genetics
POIHL 19259-03 0003 Digoxin-specific antibody in human
therapy - Synthesis of dogoxin specific antibody in
continuous cell culture (human, sheep)
ROIHL 2005402 Cultured blood vessel cells-
Pathophysiology (human, animals)
POlHL-2260201 0001 Pathophysiology of the
endothelium Platelet-endothelial interactions in vitro
(human, cattle)
VIRUS COMPONENTS
** P01HL11310-12 0100 Mechanisms of cardiovascular
disease Structure and replication of arenavirus and
Bunyamweraviruses
VIRUS COMPONENTS, CAPSID AND ENVELOPE
POlHL-1131012 0100 Mechanisms of cardiovascular
disease Structure and replication of arenavirus and
Bunyamweraviruses
VIRUS COMPONENTS, CORE
P01HL11310-12 0100 Mechanisms of cardiovascular
disease ■ Structure and replication of arenavirus and
Bunyamweraviruses
P60HL17269-04 0035 National heart and blood vessel
research and demonstration center - Blood resources-
Research program in viral hepatitis (human)
VIRUS DEVELOPMENT, REPLICATION
SEE ALSO NUCLEIC ACIDS SYNTHESIS
POlHL-0631417 0046 Immunologic mechanisms In
cardiovascular disease ■ Mediators of immune injury
(human, mice)
POlHL-09011-15 0005 A research and resource program
in blood - Characterization of hepatitis-B antigen and the
cause of serum hepatitis (human)
** POlHL-1131012 0100 Mechanisms of cardiovascular
disease ■ Structure and replication of arenavirus and
Bunyamweraviruses
ROIHLI 1822-10 Biophysical studies of macromolecular
interactions (microorganism, human)
** P60HL-17269-04 0035 National heart and blood vessel
research and demonstration center - Blood resources-
Research program in viral hepatitis (human)
R01HL17404-05 Immunologic mechanisms in heart
disease (mice)
R01HL19164-03 Piscine erythrocytic necrosis in the
Atlantic cod
ROlHL-21047-01 Studies of coxsackievirus-induced
myocarditis in mice
** ROlHL-23588-01 NOV Infection-Analysis at the subcellular
level (chickens)
VIRUS DISEASE CHARACTERISTICS,
CYTOPATHOGENIC EFFECT VIRAL
P50HL-1506107 0010 Response of lung to injury ■ An
animal model system for the study of bronchiolitis and its
sequellae (dogs)
** ROlHL-18152-03 Vascular injury and atherosclerosis
(mice, coxsackievirus)
** R01HL-19163-02 Piscine erythrocytic necrosis in the
Atlantic cod
** ROlHL-20002-03 Pulmonary complications of viral
infections (children)
VIRUS DISEASE CHARACTERISTICS, HOST-VIRUS
ROlHL-19163-02 Piscine erythrocytic necrosis in the
Atlantic cod
R01HL-19164-03 Piscine erythrocytic necrosis in the
Atlantic cod
P50HL-19171-02 0006 Pulmonary SCOR-Lung injury by
childhood infections - Development of model systems
(bacteria, viruses, hamsters)
ROlHL-19381-03 Pathogenesis of viral induced
atherosclerosis (human, chicken)
** R01HL-19651-D3 Host factors in pathogenesis of
respiratory disease (human, hamsters)
ROlHL-23588-01 NDV infection-Analysis at the subcellular
level (chickens)
(contd)
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level.
•"Oriented significantly to above subject.
M Grant has subprojerts descnbing specific research aspects.
See Appendix for investigator's name and grant number.
• .^:c:cjUutiX^iAa£»' '
VIR
VIRUS DISEASE CHARACTERISTICS, INFECTION
MECHANISMS (GENERAL)
P01HL0821415 0023 Chemical and biological properties
of lipids ■ Lipids in microorganisms and cell cultures
(hamsters, mosquitoes)
** P01HL-n310-12 0100 Mechanisms of cardiovascular
disease - Structure and replication of arenavirus and
Bunyamweraviruses
P50HL-19171-02 0006 Pulmonary SCOR-Lung injury by
childhood infections - Development of model systems
(bacteria, viruses, hamsters)
ROlHL-21047-01 Studies of coxsackievirus-induced
myocarditis in mice
VIRUS DISEASE CHARACTERISTICS, LATENT
DORAAANT OR SLOW
ROlHL-18152-03 Vascular injury and atherosclerosis
(mice, coxsackievirus)
VIRUS DISEASES
SEE ALSO COMMUNICABLE DISEASE CONTROL AGENTS
ANTIVIRAL
SEE ALSO IMMUNOLOGY, ANTIBODIES VIRAL
SEE ALSO LIVER DISORDERS, HEPATITIS SERUM
SEE ALSO LIVER DISORDERS. HEPATITIS VIRAL HUMAN
SEE ALSO NEOPLASMS, VIRUS INDUCED
SEE ALSO NERVOUS DISORDERS. MYELINOPATHIES. MULTIPLE
SCLEROSIS
SEE ALSO NERVOUS DISORDERS CENTRAL. MAREK'S DISEASE
SEE ALSO RESPIRATORY DISORDERS. URYNGOTRACHEITIS
SEE ALSO RESPIRATORY DISORDERS. PNEUMONIA VIRAL
ROlHL-01803-23 0020 Arteriosclerosis, glomerulonephritis,
rheumatic fever ■ Virus-induced arterosclerosis (chickens)
M POlHL-0631417 Immunologic mechanisms in
cardiovascular disease
Immunologic mechanisms in
Mediators of Immune injury
POlHL-06314-17 0046
cardiovascular disease
(human, mice)
POlHL-0631417 0061
cardiovascular disease
Piscine erythrocytic necrosis In the
Immunologic mechanisms in
■ Role of viruses in cardiovascular
and renal disease (human, mice)
P60HL15996-06 0005 Cincinnati comprehensive sickle
cell center - Factors precipitating crises (human)
R01HL16246-06 Immunologic studies in
postpericardiotomy syndrome (human)
ROlHL-16463-05 Localization of airways obstruction and
responses
R01HL-18152-D3 Vascular injury and atherosclerosis
(mice, coxsackievirus)
ROIHL 1820403 Regional blood flow in viral myocarditis
(turkeys)
*• R01HL19164-03
Atlantic cod
ROlHL-21829-01 Etiology of obstructive airway disease in
children (also monkeys)
ROlHL-22029-02 Bronchopulmonary resistance to bacterial
infection (mice)
VIRUS DISEASES, ARBOVIRUS, DENGUE
POlHL-08214-15 0023 Chemical and biological properties
of lipids ■ Lipids in microorganisms and cell cultures
(hamsters, mosquitoes)
VIRUS DISEASES, HERPESVIRUS
P50HLI8828-03 0006 Specialized center of research in
thrombosis ■ Etiology and pathogenesis of atherosclerosis
(rabbrt. monkey, rat, human)
VIRUS DISEASES, MYXOVIRUS, INFLUENZA
SEE ALSO VIRUSES. MYXOVIRUSES, INFLUENZA VIRUSES
P50HL1915602 0001 Pulmonary SCOR-Chronic diseases
of airways - Irritability of airways induced by epithelial
damage in healthy subjects (human)
VIRUS INDUCED NEOPLASMS
SEE NEOPLASMS. VIRUS INDUCED
VIRUS INFECTION MECHANISMS (GENERAL)
SEE VIRUS DISEASE CHARACTERISTICS. INFECTION
MECHANISMS (GENERAL)
VIRUS INHIBITORS
SEE COMMUNICABLE DISEASE CONTROL AGENTS. ANTIVIRAL
VIRUS PNEUMONIA
SEE RESPIRATORY DISORDERS, PNEUMONIA VIRAL
VIRUS REPLICATION
SEE VIRUS DEVELOPMENT, REPLICATION
VIRUSES
SEE ALSO CHLAMYDIA
SEE ALSO EXPERIMENTAL VIROLOGY STUDY SECTION
SEE ALSO IMMUNOLOGY, INTERFERON
ROlHL-21831-05 Determining sequences from hemoglobin
messenger RNA (mice, chickens, rabbits)
VIRUSES, ADENOVIRUSES
P50HLI4136-07 0003 Pulmonary SCOR-Airways
obstructive diseases ■ Acute pediatric respiratory disease
and COLD
" P50HL 15061-07 0010 Response of lung to injury ■ An
animal model system for the study of bronchiolitis and its
sequellae (dogs)
520
VIRUSES, ARBOVIRUSES (GENERAL)
POlHL-082 14-15 0023 Chemical and biological properties
of lipids - Lipids in microorganisms and cell cultures
(hamsters, mosquitoes)
** POlHL-11310-12 0100 Mechanisms of cardiovascular
disease - Structure and replication of arenavirus and
Bunyamweraviruses
VIRUSES, ARBOVIRUSES, HEMORRHAGIC FEVER
VIRUSES
POIHLI 13 10-12 0100 Mechanisms of cardiovascular
disease - Structure and replication of arenavirus and
Bunyamweraviruses
VIRUSES, ARBOVIRUSES B, JAPANESE B
ENCEPHALITIS VIRUS
POIHL-08214-15 0023 Chemical and biological properties
of lipids - Lipids in microorganisms and cell cultures
(hamsters, mosquitoes)
VIRUSES, ARENAVIRUSES
" POIHLI 13 10-12 0100 Mechanisms of cardiovascular
disease - Structure and replication of arenavirus and
Bunyamweraviruses
VIRUSES, HEPATITIS
SEE ALSO LIVER DISORDERS. HEPATITIS SERUM
SEE ALSO LIVER DISORDERS. HEPATITIS VIRAL HUMAN
P60HL- 17269-04 0035 National heart and blood vessel
research and demonstration center - Blood resources -
Research program in viral hepatitis (human)
VIRUSES, HEPATITIS A VIRUS (HAV)
SEE ALSO LIVER DISORDERS. HEPATITIS VIRAL HUMAN
ROlHL-22838-01 Post-transfusion hepatitis in newborn
children
VIRUSES, HEPATITIS B VIRUS (HBV)
SEE ALSO IMMUNOLOGY, ANTIGENS VIRAL. HEPATITIS B
ANTIGEN (HBAG)
SEE ALSO LIVER DISORDERS, HEPATITIS VIRAL HUMAN
ROlHL-22838-01 Posttransfusion hepatitis in newborn
children
VIRUSES, HERPESVIRUSES
SEE ALSO NERVOUS DISORDERS CENTRAL. MAREK'S DISEASE
ROlHL-01803-23 0020 Arteriosclerosis, glomerulonephritis,
rheumatic fever - Virus-induced arterosclerosis (chickens)
** ROlHL-19381-03 Pathogenesis of viral induced
atherosclerosis (human, chicken)
VIRUSES, HERPESVIRUSES,
CYTOMEGALOVIRUSES
POlHL-06314-17 0046 Immunologic mechanisms in
cardiovascular disease - Mediators of immune injury
(human, mice)
POlHL-063 14-17 0061 Immunologic mechanisms in
cardiovascular disease - Role of viruses in cardiovascular
and renal disease (human, mice)
ROlHL-22838-01 Post-transfusion hepatitis in newborn
children
VIRUSES, HERPESVIRUSES, EB VIRUS
ROlHL-22838-01 Post-transfusion hepatitis in newborn
children
VIRUSES, MYXOVIRUSES, INFLUENZA VIRUSES
SEE ALSO VIRUS DISEASES. MYXOVIRUS. INFLUENZA
P50HL-14136-07 0003 Pulmonary SCOR-Airways
obstructive diseases ■ Acute pediatric respiratory disease
and COLD
ROlHL-20002-03 Pulmonary complications of viral
infections (children)
VIRUSES, MYXOVIRUSES, MEASLES VIRUS
ROlHL-20002-03 Pulmonary complications of viral
infections (children)
VIRUSES, MYXOVIRUSES, RESPIRATORY
SYNCYTIAL VIRUSES
P50HL-14136-07 0003 Pulmonary SCOR-Airways
obstructive diseases - Acute pediatric respiratory disease
and COLD
P50HL-191 57-02 0011 Studies in cystic fibrosis and
bronchiolitis - Pathogenesis of bronchiolitis (children)
ROlHL-19651-03 Host factors in pathogenesis of
respiratory disease (human, hamsters)
ROlHL-20002-03 Pulmonary complications of viral
infections (children)
VIRUSES, ONCORNA, LEUKEMIA MOUSE
POlHL-21016-02 0012 Sickle cell anemia and other
hemoglobinopathies - Stimulation of Hb F synthesis in a
permanent cell line
VIRUSES, ONCORNA, LEUKEMIA MOUSE
RAUSCHER
ROlHL-03357-21 Humoral control of blood cell formation
and release (rats, mice)
VIRUSES, PAPOVAVIRUSES, SV40 VIRUS
ROlHL-20054-02 Cultured blood vessel cells-
Pathophyslology (human, animals)
VIT
VIRUSES, PARAMYXOVIRUSES, NEWCASTLE
DISEASE VIRUS
ROlHL-23588-01 NDV infection-Analysis at the subcellular
level (chickens)
VIRUSES, PARAMYXOVIRUSES, PARAINFLUENZA
VIRUSES
P50HL-14136-07 0003 Pulmonary SCOR-Airways
obstructive diseases - Acute pediatric respiratory disease
and COLD
ROlHL-19651-03 Host factors in pathogenesis of
respiratory disease (human, hamsters)
ROlHL-20002-03 Pulmonary complications of viral
infections (children)
VIRUSES, PICORNAVIRUSES, COXSACKIE
VIRUSES
POlHL-06314-17 0061 Immunologic mechanisms in
cardiovascular disease - Role of viruses in cardiovascular
and renal disease (human, mice)
ROlHL-18152-03 Vascular injury and atherosclerosis
(mice, coxsackievirus)
R01HL-18535-03 Epidemiology and course of viral
myopericarditis (human)
P01HL18645-03 0006 Biology of the artery wall and
atherosclerosis - The platelet and atherosclerosis (monkeys,
baboons)
ROlHL-21047-01 Studies of coxsackievirus-induced
myocarditis in mice
VIRUSES, RESPIRATORY (GENERAL)
SEE ALSO VIRUSES. ADENOVIRUSES
SEE ALSO VIRUSES. MYXOVIRUSES. INFLUENZA VIRUSES
SEE ALSO VIRUSES, PARAMYXOVIRUSES, PARAINFLUENZA
VIRUSES
Pulmonary SCOR-Airways
- Acute pediatric respiratory disease
P50HL-14136-07 0003
obstructive diseases
and COLD
P50HL-14136-07 0017
obstructive diseases
(human)
P50HL-14212-07 0006
Pulmonary SCOR-Airways
Pediatric airways obstructive disease
Correlated studies of pulmonary
- Alveolar macrophage physiology (human, rodents.
•Excludes routine methodotogy OR covers only general projects which preclude indexing
Onented significantly to above subject.
atthespecificlevel.
M Grant has subprojects describing specific research aspects
See Appendix for investigators name and grant number
fibrosis
rabbits)
*• P50HL14212-07 0015 Correlated studies of pulmonary
fibrosis - Pulmonary defense mechanisms and fibrotic lung
disease (rodents, rabbits)
P50HL-15389-07 0019 Pulmonary SCOR-Hypersensitivify
pneumonitis - Microbiology core (human, animal)
" P50HL-19157-02 0011 Studies in cystic fibrosis and
bronchiolitis - Pathogenesis of bronchiolitis (children)
VIRUSES, RNA VIRUSES (GENERAL)
SEE ALSO NUCLEIC ACIDS, RNA VIRAL
ROIHL- 10980- 11 Ultrastructural renal pathology (human,
rats)
VIRUSES, TOGAVIRUSES, RILEY VIRUS
POlHL-06314-17 0046 Immunologic mechanisms in
cardiovascular disease - Mediators of immune injury
(human, mice)
VISCERAL AFFERENT NERVES
SEE NERVOUS SYSTEM, AFFERENT NERVES, VISCERAL
AFFERENT NERVES
VISCOSITY-VISCOELASTICITY
SEE PHYSICAL PROPERTIES, VISCOSITY-VISCOEUSTICITY
VISCOSITY-VISCOELASTICITY, BLOOD
SEE BLOOD VISCOSITY-VISCOELASTICITY
VISCOSITY-VISCOELASTICITY, BODY FLUID
SEE BODY FLUIDS, VISCOSITY-VISCOEUSTICITY
VISION
SEE EYE. VISION
VISUAL AIDS
SEE EDUCATION. AUDIOVISUAL AND OTHER TRAINING AIDS
VISUAL FIELDS
SEE EYE, VISUAL FIELDS
VISUAL PATHWAYS
SEE BRAIN, VISUAL PATHWAYS
VISUAL PERCEPTION
SEE EYE, VISUAL PERCEPTION
VISUAL PIGMENTS
SEE EYE, VISUAL PIGMENTS
VISUAL STIMULUS
SEE EYE, VISUAL STIMULUS
VISUAL TRACKING
SEE PSYCHOMOTOR FUNCTION, VISUAL TRACKING
VISUALIZATION
SEE CARDIOVASCULAR VISUALIZATION*
SEE CEREBROVASCULAR VISUALIZATION*
SEE GASTROINTESTINAL VISUALIZATION*
SEE HEART VISUALIZATION-
SEE KIDNEY VISUALIZATION*
SEE OPTICS, IMAGING-VISUALIZATION (GENERAL)*
SEE RESPIRATORY VISUALIZATION*
(contd)
VIT
VITAL CAPACITY
SEE RESPIRAIORY FUNCTION. RESPIRATORY AIRWAY VOLUME
VHAMIN ANTAGONISTS
ROIHI 156190S Rejulation ot piolhiombm synthesis in
cultured calls (i>ts)
*• ROIHL 197?2 02 Role ot werlann metabolism in
inlivitamin K activity (tats)
VnAMIN A
SEE ALSO NUTRITIONAL ABNORMALITIES. HYPOVITAMINOSIS A
ROIHL 06481 IS Lipid metabolism (human, tats)
•• P50HL 14214 07 0023 Newborn lung centei loi hyaline
membiane disease Reiulation ot tetal lung maturation •
Vitamin A (rat. rabbit, sheep, human)
** P50HL 1423605 0001 Prevention ot premature
arteriosclerosis Metabolism and transport ot cholesterol
and vitamin A (human, rats)
•• ROIHL 15341 06 Lung hormonal and chromosomal
regulation (rats, rabbits)
ROIHL 1907203 Modification ot tissue injury in
myocardial intarction (dogs, human)
** P50HL 2100602 0003 Specialized center ot research in
arteriosclerosis ■ Transport of vitamin A in plasma (human.
rat)
VITAMIN A ACID
ROIHL 1534106 Lung hormonal and chromosomal
regulation (rats, rabbits)
VITAMIN A DEFICIENCY
SEE NUTRITIONAL ABNORMALITIES. HYPOVITAMINOSIS A
VITAMIN B, BIOTIN
P01HL1141411 0035 Thrombosis and atherosclerosis
program ■ Mechanism of action of vitamin K (rats)
R01HL16628-05 Regulation of lipid metabolism (rats)
VITAMIN B, LIPOIC ACID
** ROlHL-2191201 Biosynthesis of lipoic acid and
atherosclerosis (birds, chick embryos)
VITAMIN B2
SEE FLAVIN NUCLEOSIDES, RIBOFUVIN
VITAMIN B3
SEE PYRIDINAMIDES. NICOTINAMIDE
VITAMIN B6, PYRIDOXAL ANALOGS
** ROlHL-17552-03 Sickling inhibition by chemical
modification of hemoglobin (human)
VITAMIN B12
R01HL-20996-02 Structural and reactivity of iron and
cobalt complexes
VITAMIN BC
SEE FOLIC ACID
VITAMIN C
SEE ALSO NUTRITIONAL ABNORMALITIES, HYPOVITAMINOSIS C
POlHL-06314-17 0053 Immunologic mechanisms in
cardiovascular disease - Cellular functions controlled by
cyclic GMP (human, mice, guinea pigs)
P01HL0683517 0016 Cardiovascular disease - Metabolic
interactions to polyunsaturated fatty acids in atherogenic
diet (dogs)
POlHL-06835-17 0021 Cardiovascular disease ■ Animal
study in atherosclerosis (dog, guinea pig)
** POlHL-06835-17 0026 Cardiovascular disease ■
Lipoproteins (human, guinea pig)
POlHL-06835-17 0064 Cardiovascular disease - Studies
in atherosclerosis (human, animals)
ROlHL-12256-15 Polymerization of sickle-cell hemoglobin
(human)
R01HL-19961-03 Management of hemosiderosis in
thalassemia (children, adults)
ROlHL-20783-02 Airway reactivity-B-adrenoceptors and
prostaglandins (guinea pigs)
VITAMIN C DEFICIENCY
SEE NUTRITIONAL ABNORMALITIES, HYPOVITAMINOSIS C
VITAMIN D GROUP, VITAMIN D
ROlHL-15504-05 Animal model for studies on averting
atherosclerosis (swine)
** f(01HL- 19399-02 Atherosclerosis-Early events and
regression factors (rats)
VITAMIN D
SEE VITAMIN D GROUP, VITAMIN D
VITAMIN E
** ROlHL-06481-15 Lipid metabolism (human, rats)
** POlHL-07896-15 0030 Environmental biomedical research
program - Narcosis caused by inert gases at raised
pressures (human, animals)
ROlHL-1189711 Pathogenesis of experimental
atherosclerosis (rabbits, guinea pigs)
P50HL-15061-07 0012 Response of lung to injury -
Hyperbaric oxygen, carbon monoxide, and ozone or peroxide
toxicity (rats)
Aging-tissue injury and repair (rats)
Airborne metals and lung permeability
R01HL-16330-06
ROlHL-16674-05
(bullfrogs, rats)
ROlHL-17719-03
Lung injury, substrate utilization, oxygen
toxicity (rats, rabbits, dogs)
531
*• ROIHL 21431 02 Factor II antigen and coagulant activity
(human, animals)
•• ROIHI 22951 01 Studies on the affect ot vitamin E on
platelets (human, rats)
** P60HI 23282 01 0003 Comprehensive hospital/community
sickle cell center Treatment of sickle cell ulcers with
physical therapy and vitamin E (human)
VITAMIN E DEFICIENCY
SEE NUTRITIONAL ABNORMALITIES. HYPOVITAMINOSIS E
VITAMIN G
SEE FUVIN NUCLEOSIDES. RIBOFLAVIN
VITAMIN H
SEE VITAMIN B, BIOTIN
VITAMIN K
** POIHL 11414 11 0035 Thrombosis and atherosclerosis
program Mechanism of action of vitamin K (rats)
P50HL-14147 08 0003 Specialized center of research in
thrombosis • Surtace thrombogenicity and phospholipid
vesicle physical properties
** R01HL14847-07 Mechanism ot action of vitamin K and
anticoagulants (rats)
** ROIHL 15619-05 Regulation of prothrombin synthesis in
cultured cells (rats)
*• ROIHL 15728-06 The carbohydrate of the blood-clotting
glycoproteins (mammals)
ROIHL- 1 88 34-04 Metal-dependent complex formation in
blood coagulation (human, cattle)
** ROlHL-19322 03 Role of pituitary hormones in the action
of vitamin K (rats)
** ROlHL-197 72-02 Role of warfarin metabolism in
antivitamin K activity (rats)
ROlHL-19982-02 Blood coagulation-Protein-metal ion-lipid
interactions
R01HL-20161-02 Role of gamma-carboxyglutamic acid in
blood coagulation (human, cattle)
" ROlHL-20577-03 The mechanism of action of vitamin K
ROlHL-211 13-01 Control mechanisms in coagulation
(cattle)
** ROlHL-21543-02 Structure-function relation of blood
clotting proteins (rabbits)
VITAMIN K DEFICIENCY
SEE NUTRITIONAL ABNORMALITIES, HYPOVITAMINOSIS K
VITAMIN K3
ROlHL-19532-01 Oxygen toxicity in the red cell (human)
VITAMIN M
SEE FOLIC ACID
VITAMIN P
SEE FLAVONOIDS
VITAMIN PP
SEE PYRIDINAMIDES, NICOTINAMIDE
VITAMIN THERAPY
SEE NUTRITION, DIET THERAPEUTIC, VITAMIN THERAPY (ALL
ROUTES OF ADMINISTRATION)
VITAMINS BIOSYNTHESIS
** ROIHL 21912-01 Biosynthesis of lipoic acid and
atherosclerosis (birds, chick embryos)
VITAMINS METABOLISM
ROlHL-06481-15 Lipid metabolism (human, rats)
** P50HL-14236-05 0001 Prevention of premature
arteriosclerosis - Metabolism and transport of cholesterol
and vitamin A (human, rats)
ROlHL-14847-07 Mechanism of action of vitamin K and
anticoagulants (rats)
VITRECTOMY
SEE EYE SURGERY. VITRECTOMY
VITREOUS BODY
SEE EYE, VITREOUS BODY
VITREOUS HEMORRHAGE
SEE EYE CIRCULATORY DISORDERS, RETINAL (INCLUDING
VITREOUS) HEMORRHAGE
VLDL (LIPOPROTEINS)
SEE LIPOPROTEINS BLOOD. VLDL
VOCATIONAL GUIDANCE
SEE OCCUPATIONS, VOCATIONAL GUIDANCE
VOCATIONAL REHABILITATION
SEE HEALTH CARE SERVICES, REHABILITATION VOCATIONAL
VOLUNTARY HEALTH ORGANIZATIONS
SEE HEALTH AND SCIENTIFIC ORGANIZATIONS. VOLUNTARY
HEALTH ORGANIZATIONS
VOMITING
SEE GASTROINTESTINAL DISORDERS, EMESIS
VON WILLEBRAND'S DISEASE
SEE BLOOD COAGULATION DISORDERS, VON WILLEBRAND'S
DISEASE
WARFARIN
SEE BENZO-ALPHA-PYRONES. WARFARIN
WAT
WATER
SU ALSO BIOIOGICAI TRANSPORT, flUlO tXCHAHCE AND
TRANSPORT
SEE ALSO BODY FLUID BALANCE, BODY WATER
SEE ALSOCEll FLUIDS, CELL WATER
SEE Also CHFMICAI Rf ACTIONS, HYDRATION
SEE ALSO CHFMICAI REACTIONS. SOIVOIYSIS. HYDROLYSIS
SEE ALSO PHYSICAL PROPfRTIfS. SOIUTIONS. AQUEOUS
** ROIHL 1398905 Role of water in respiratiory protein
structure
ROIHL 19491 03 Mechanism of iron storage and
mobilization by ferritin (horse)
ROIHL 2256902 Intestinal secretion Capillary and tissue
forces (dogs, cats)
WATER BREATHING
SEE RESPIRATORY FUNCTION. LIQUIDS BREATHING
WATER-ELECTROLYTE BALANCE
SEE BODY FLUID BAIAN^r 'O'l
WATER ENVIRONMENT, AQUATIC BIOLOGY
SEE ALSO ARTHROPODS, CRUSTACEANS-
SEE ALSO FISH*
SEE ALSO MOLLUSKS*
P01HL08805-15 0006 Regulation of ventilation and
pulmonary circulation Adaptation of lungfish Estivation
WATER ENVIRONMENT, AQUATIC ORGANISMS,
FRESH WATER*
ROIHL 14523 07 Generation and regulation of force in
smooth muscle (animals)
WATER ENVIRONMENT, DIVING AND
SWIMMING
SEE ALSO ENVIRONMENT, ATMOSPHERIC PRESSURE.
COMPRESSION-DECOMPRESSION
SEE ALSO INJURIES. DYSBARISM
M POlHL-07896-15 Environmental biomedical research
program
** POlHL-07896-15 0008 Environmental biomedical research
program - Otologic studies under hyperbaric conditions
(human, animals)
** POlHL-07896-15 0009 Environmental biomedical research
program - Decompression sickness and computation of safe
diving tables (human, animals)
** POlHL-07896-15 0021 Environmental biomedical research
program - Liquid breathing and lung lavage (human)
** POlHL-07896-15 0029 Environmental biomedical research
program - Oxygen-helium diving resulting in high pressure
nervous syndrome (human, animals)
** POlHL-07896-15 0036 Environmental biomedical research
program - Respiratory heat loss in deep diving (Infants,
dogs)
*• POlHL-07896-15 0048 Environmental biomedical research
program - Respiratory performance in divers at 1400 FSW
** POlHL-07896-15 0061 Environmental biomedical research
program - Oxygen cost of breathing during graded exercise
(human)
** POlHL-07896-15 0062 Environmental biomedical research
program - Vectorcardiograms during diving (human, dogs)
M POlHL-08899-14 Tolerance to respiratory gases in health
and disease
Tolerance to respiratory gases in
Oxygen tolerance (human, rats.
POlHL-08899-14 0020
health and disease
guinea pigs)
POlHL-08899-14 0064
health and disease
Tolerance to respiratory gases in
Narcotic effects of inert gases on
functional systems (rats)
POlHL-08899-14 0072 Tolerance to respiratory gases in
health and disease - Inert gas exchange isobaric gas
counterdiffusion and decompression
POlHL-14388-07 0208 Regulation of the circulation in
pathological states - Baroreceptor reflex function in normal
and hypertensive man
M POlHL-14414-07 Environmental influences on
cardiorespiratory and cellular functions
** POlHL-14414-07 0008 Environmental influences on
cardiorespiratory and cellular functions - Energetics of
swimming (human)
ROlHL-16254-05 Pathogenesis of bubble and clot
formation (fish)
POlHL-17731-04 0003 Physiological basis of pulmonary
disease - Comparative physiology (vertebrates)
M ROlHL-17896-03 Dehydropeptide renin substrates
** R01HL-22406-01 Isobaric vascular bubbles and
decompression sickness (goats, models)
ROlHL-22413-01 Enhanced detection of bubbles in
Soppier flow signals (human)
WATER ENVIRONMENT, DIVING REFLEX
** P50HL-14214-07 0029 Newborn lung center for hyaline
membrane disease - The diving reflex-Perinatal asphyxia,
pulmonary ischemia and HMD (sheep)
WATER ENVIRONMENT, MARINE BIOLOGY
SEE ALSO WATER ENVIRONMENT. DIVING AND SWIMMING
SEE ALSO WATER ENVIRONMENT. OCEANIC RESEARCH
** POlHL-07896-15 0060 Environmental biomedical research
program - Effect of pressure on development of marine
crustacean larvae
** ROlHL-15460-06 Molecular adaptation-Hemoglobin
systems of fish (marine)
(contd)
'Excludes routine methodology OR covers only general proiects which preclude i
"Oriented significantly to above subject.
indexing at the specific level.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
WAT
ROlHL-15991-05 Evaluation of heart stimulants in sea
anemones
ROlHL-18868-03 Development of vertebrate vascular
control systems (reptiles, amphibians)
ROlHL-19163-02 Piscine erythrocytic necrosis in the
Atlantic cod
ROlHL-19164-03 Piscine erythrocytic necrosis in the
Atlantic cod
WATER ENVIRONMENT, OCEANIC RESEARCH
SEE ALSO WATER ENVIRONMENT, MARINE BIOLOGY
" POlHL-1773104 0003 Physiological basis of pulmonary
disease - Comparative physiology (vertebrates)
WATER INTAKE DRIVE
SEE NUTRIENT INTAKE ACTIVITY, THIRST
WATER INTOXICATIJN
SEE BODY FLUID BAUNCE. BODY WATER EXCESS
WATER LOSS, BODY WATER
SEE BODY FLUID BALANCE, BODY WATER LOSS
WATER QUALITY
** R01HL-19073-O2 Heart disease and drinking water at
home
WATER SOLUBILITY
SEE PHYSICAL PROPERTIES. SOLUBILITY, WATER
WAVESHAPE PROCESSING ANALYSIS AND
DISPLAY
SEE OPTICS, IMAGE PROCESSING ANALYSIS AND DISPUY*
WAXES (LIPID)
SEE LIPIDS. WAXES
WEANLING (ANIMAL)
SEE AGE (ANIMAL), WEANLING
WEAR AND TEAR PIGMENT
SEE LIPOFUSCINCEROIO
WEATHER
SEE ENVIRONMENT, ATMOSPHERE (WEATHER)
WELFARE SERVICE NONPSYCHIATRIC
SEE SOCIAL SERVICES (GENERAL)
WELFARE SERVICES PSYCHIATRIC
SEE MENTAL HEALTH SERVICES, SOCIAL SERVICE
PSYCHOSOCIAL
WELFARE SERVICES PSYCHOSOCIAL
SEE MENTAL HEALTH SERVICES, SOCIAL SERVICE
PSYCHOSOCIAL
WHIPLASH INJURIES
SEE INJURIES. HEAD AND NECK
WHITE AMERICANS
SEE SOCIAL GROUPS. ETHNIC, AMERICANS, WHITE
AMERICANS
WHITE RACE
SEE SOCIAL GROUPS, RACIAL STOCKS, WHITE RACE
WHO
SEE HEALTH AND SCIENTIFIC ORGANIZATIONS,
INTERNATIONAL, WHO
WHOLE BODY PERFUSION (TOTAL BLOOD
REPLACEMENT)
SEE BLOOD TREATMENT, WHOLE BODY PERFUSION (BLOOD
REPLACEMENT)
WILM'S TUMOR
SEE NEOPLASMS OF URINARY TRACT, KIDNEY NEOPLASMS
NEPHROBLASTOMA
WILSON'S DISEASE
SEE METABOLIC DISORDERS INBORN, HEPATOLENTICULAR
DEGENERATION
WITHDRAWAL, DRUG
SEE DRUGS WITHDRAWAL (SYMPTOMS)
WOLFF-PARKINSON-WHITE SYNDROME
SEE CONGENITAL ABNORMALITIES, HEART DEFECTS, WOLFF-
PARKINSON-WHITE SYNDROME
WOLMAN'S DISEASE
SEE METABOLIC DISORDERS INBORN, LIPID (NEUTRAL)
STORAGE, WOLMAN'S DISEASE
WOMEN
SEE SEX, FEMALE
WOOLLY MONKEYS
SEE MAMMALS, PRIMATES. MONKEYS AND APES
(ANTHROPOIDS. NON-HUMAN). NEW WORLD MONKEYS
(PLATYRHINES)*
WORK
SEE OCCUPATIONS
WORKSHOP
SEE INFORMATION DISSEMINATION, MEETINGS CONFERENCES
SYMPOSIA, WORKSHOP
522
WORLD HEALTH ORGANIZATION
SEE HEALTH AND SCIENTIFIC ORGANIZATIONS.
INTERNATIONAL, WHO
WOUND HEALING
SEE INJURIES, WOUND HEALING
WOUNDS
SEE INJURIES, WOUNDS
XANTHINE(S)
SEE PURINES. XANTHINES
XANTHOMA TUBEROSUM MULTIPLEX
SEE METABOLIC DISORDERS INBORN,
HYPERLIPOPROTEINEMIAS FAMILIAL, TYPE II
XANTHOMATOSIS
SEE LIPOIDAL DISORDERS. XANTHOMATOSIS
XANTHOMATOSIS, CEREBROTENDINOUS
SEE LIPOGRANULOMATOSES, CEREBROTENDINOUS
XANTHOMATOSIS
XANTHOMATOSIS (FAMILIAL) WITH ADRENAL
CALCIFICATION
SEE METABOLIC DISORDERS INBORN. LIPID (NEUTRAL)
STORAGE. WOLMAN'S DISEASE
X CHROMOSOME
SEE GENETICS. CHROMOSOMES. SEX CHROMOSOMES
XENOGRAFT
SEE TISSUE COMPATIBILITY-TRANSPUNT. TRANSPLANTATION
HETEROLOGOUS
XENON
SEE GAS ELEMENTS, XENON
XENON RADIOISOTOPES (133)
SEE RADIOISOTOPES. XENON
XERODERMOSTEOSIS
SEE CONNECTIVE TISSUE DISORDERS. SJOGREN'S SYNDROME
XEROGRAPHIC RADIOGRAPHS
SEE RADIOGRAPHY, XEROGRAPHY
XEROGRAPHY
SEE RADIOGRAPHY, XEROGRAPHY
X-RAY DENSITOMETRY
SEE PHYSICAL PROPERTIES, DENSITOMETRY*
X-RAY DIFFRACTION (CHEMISTRY)
SEE CHEMISTRY. ANALYTICAL METHODS. X-RAY STRUCTURE
ANALYSIS*
X-RAY MICROANALYSIS (ELECTRON PROBE)
SEE CHEMISTRY, ANALYTICAL METHODS, SPECTROMaRY
ELECTRON PROBE*
X-RAY RADIOGRAPHY
SEE RADIOGRAPHY*
X-RAY SCANNING
SEE RADIOGRAPHY, SCANNING (GENERAL)*
X-RAY SCATTERING (CHEMISTRY)
SEE CHEMISTRY, ANALYTICAL METHODS, X-RAY STRUCTURE
ANALYSIS*
X-RAY SPECTROMETRY
SEE CHEMISTRY, ANALYTICAL METHODS. SPECTROMETRY X-
RAY*
X-RAY STRUCTURE ANALYSIS (CHEMISTRY)
SEE CHEMISTRY. ANALYTICAL METHODS. X-RAY STRUCTURE
ANALYSIS*
X-RAY VIDEODENSITOMETRY
SEE CARDIOVASCUUR VISUALIZATION, ROENTGEN
VIDEODENSITOMETRY*
XYLOSE
SEE PENTOSES, XYLOSE
Y CHROMOSOME
SEE GENETICS. CHROMOSOMES, SEX CHROMOSOMES
YOGA
SEE PSYCHIC ACTIVITY LEVEL, TROPHOTROPIC STATE
MEDITATION
YOHIMBINE
SEE ALKALOIDS, RAUWOLFIA TYPE, YOHIMBINE
YOUNG ADULTS
SEE AGE (HUMAN). ADULT. YOUNG (21 TO 44 YRS)
YOUNG (ANIMAL)
SEE AGE (ANIMAL), JUVENILE (POST-INFANCY TO PUBERTY)
YOUTH
SEE CHILDREN
YOUTH MENTAL HEALTH (SERVICES)
SEE MENTAL HEALTH (SERVICES), YOUTH
Z PROTEIN (FATTY ACID BINDING PROTEIN)
SEE PROTEINS, Z PROTEIN
ZYM
ZAZEN
SEE PSYCHIC ACTIVITY LEVEL, TROPHOTROPIC STATE
MEDITATION
ZEUWEGER SYNDROME
SEE METABOLIC DISORDERS INBORN, CEREBRO-HEPATO-
RENAL SYNDROME
ZEN BUDDHISM
SEE PSYCHIC ACTIVITY LEVEL, TROPHOTROPIC STATE
MEDITATION
ZETA POTENTIAL
SEE ELECTROPOTENTIALS. ZETA POTENTIAL
ZINC (COMPOUNDS)
SEE METALS, HEAVY METALS, ZINC
ZYMOGENS
SEE ENZYMES, ZYMOGENS
ZYMOHEXASE
SEE ALDOUSES
ZYMOSAN
SEE IMMUNOLOGY. ANTIGENS MICROBIAL. ZYMOSAN
•Excludes routine methodology OR covers only general projects which preclude indexing at the specific level
Oriented significantly to above subject.
M Grant has subprojects describing specific research aspects.
See Appendix for investigator's name and grant number.
(contd)
V*.:
:?<;
S23
NOIHt-319190* (HCRO) OIEDIRICH. DINNIS. KANSAS CITY. KANSAS.
Hemojlobin caibamylolion in the lieatmeni ol sickle cell anemia
(human, dots)
N0)HB-22933-0« (HCRO) BALCERZAK, STANLEY P. COLUMBUS. OHIO Develop
ettective Iheiapy toe sicKle cell disease (human, dogs)
N01HB-4a97»-H (HCRO) MOOR-JANKOWSKU, JAN, NEW YORK. NEW YORK
Chimpaniees loi hepatitis reseaich
NO1HB-5S016-O5 (HCRO) MC MIllAN. C W, CHAPEL HILL. NORTH CAROLINA
Cooperative study ot tactoc VIII inhibitors in patients with hemophilia
N0IMB-530T8-04 (HCRO) SHAPIRO. SANOOR S. PHIUOELPHIA. PENNSYLVANIA
Cooperative studies ol factor VIII inhibitors in patients with hemo
philia
N0tHB.530T9.06 (HCRO) lEVINE, PETER H, WORCESTER. MASSACHUSEHS
Cooperative study ot factor VIII inhibitors in patients with hemophilia
N01HB-S3020-04 (HCRO) AlEOORT, lOUIS M, NEW YORK. NEW YORK Coopera
tive study of tactor VIII inhibitors in patients with hemophilia
N01HB-53021-0S (HCRO) EYSTER, M ELAINE, HERSHEY. PENNSYLVANIA.
Cooperative study of factor VIII inhibitors in patients with hemophilia
N01HB-S3023-04 (HCRO) HATHAWAY, WILLIAM E, DENVER, COLORADO
Cooperative study ol factor VIII inhibitors in patients with hemophilia.
NOIHB-53024-04 (HCRO) GOODNIGHT, SCOTT, PORTLAND. OREGON Coopera-
tive studies ot factor VIII inhibitors in patients with hemophilia
N01HB-5302S-0S (HCRO) LUSHER, JEANNE M, DETROIT. MICHIGAN Cooperative
Studies of factor Vlll inhibitors in patients with hemophilia.
NOlHB-53035-04 (HCRO) SHAPIRO, SANDOR S, PHILADELPHIA. PENNSYLVANIA.
Factor Vlll inhibitors in patients with hemophilia.
NOIHB-62908-07 (HCRO) SZMUNESS, WOLF, NEW YORK. NEW YORK. Maternal
to infant transmission of hepatitis B (human),
N01HB-62962-02 (HCRO) FINCH, CLEMENT A, SEATTLE. WASHINGTON. Red cell
distributions in cyanatetreated blood (human, sheep).
NOlHB-62963-03 (HCRG) BORTIN, MORTIMER M, MILWAUKEE. WISCONSIN In
ternational bone marrow transplant registry.
N01HB-62964-03 (HCRG) RIMM, ALFRED A, MILWAUKEE. WISCONSIN Interna
tional bone marrow transplant registry
N01HB-62967-03 (HCRG) LIEN, DONNA M, ARLINGTON. VIRGINIA. Blood banking
services on a regional basis.
N01HB-6296B-07 (HCRG) SWITALSKI, RICHARD, ARLINGTON. VIRGINIA. National
blood banking data needs.
NOIHB-62970-02 (HCRG) HERZIG, GEOFFREY P, ST LOUIS. MISSOURI. Collec-
tion, function and transfusion of granulocytes.
NOIMB.62971-03 (HCRG) GALE, ROBERT P, LOS ANGELES. CALIFORNIA. Collec-
tion, function and transfusion of granulocytes.
N01HB-62972-0S (HCRG) MC CULLOUGH, JEFFREY, MINNEAPOLIS. MINNESOTA.
Collection, function and transfusion of granulocytes.
N01HB-62973-0S (HCRG) STRAUSS, RONALD G, IOWA CITY. IOWA. Collection.
function and transfusion of granulocytes.
N01HB-729I6-02 (HCRG) BREWER, GEORGE J, ANN ARBOR. MICHIGAN. Crisis
and pain symptom prophylaxis by oral zinc therapy (human).
N01HB-72982-03 (HCRG) CHEN, EDWIN H, CHICAGO. ILLINOIS. Statistical coor-
dinating center for sickle cell disease.
NOlHB-82924-00 (HCRG) MURPHY M J JR, NEW YORK. NEW YORK Source of
human urinary erythropoietin.
N01HB-82926-00 (HCRG) DUKES, PETER P, LOS ANGELES. CALIFORNIA. Source of
human urinary erythropoietin.
N01HI.022 16-10 (HCRG) SANCES, ANTHONY, JR, MILWAUKEE. WISCONSIN. To
develop biological flow NMR concept (human, mammals non human).
N01HI-32926-10 (HCRG) INNERARITY, THOMAS L, SPRINGFIELD. VIRGINIA
Analysis of lipoproteins (animals).
N01HI-72900-01 (HCRG) JUDY, JESSE N, LURAY. VIRGINIA. Maintenance of the
NHLBl sheep colony.
N01HI-72947-01 (HCRG) DETRE, KATHERINE M, PIHSBURGH. PENNSYLVANIA.
Coordination center-Coronary intervention.
ROIHl-00082-30 (PHY) ROOS, ALBERT, WASHINGTON UNIVERSITY, 660 SOUTH
EUCLID. ST LOUIS. MO. Transmembrane movements (barnacles, frogs,
rats).
R01HL-00340-29 (CVB) GOLDBERG, MARTIN, HOSP OF UNIV OF PENNSYLVANIA.
3400 SPRUCE ST. 860 GATES BLDG, PHILADELPHIA, PA. Electrolyte
disturbance in cardio-renal disease (human, dogs, rats).
ROIHl.00487-29 (CVA) GREEN, HAROLD D, BOWMAN GRAY SCHOOL OF
MEDICINE. 300 SOUTH HAWTHORNE ROAD. WINSTON SALEM. N C.
Vasomotor tone and venous return (human, dogs, monkeys.
R01HL-00759-29 (CVB) COHEN, JORDAN J, NEW ENGLAND MEDICAL CTR HOSP.
171 HARRISON AVENUE. BOSTON. MASS. Regulation of electrolyte and
acid base equilibrium (dogs).
R01HL-0101S-27 (CVB) HAWTHORNE, EDWARD W, HOWARD UNIVERSITY. 520
W STREET. N W. WASHINGTON. D C. Hypertension and left ventricular
hypertrophy (dogs).
R01HL-01486.23 (CVB) LEPESCHKIN, EUGENE, CARDIOVASCULAR RESEARCH
UNIT. C-449 GIVEN BUILDING. BURLINGTON. VT. Quantitative study of
T-wave mechanisms (human, rabbits, dogs, chickens).
R01HL.01601-30 (HEM) LEVIN, JACK, JOHNS HOPKINS HOSPITAL. 601 NORTH
BROADWAY. BALTIMORE. MD. Blood coagulation and hemorrhagic dis-
ease (horseshoe crabs).
ROIHl-01623-24 (PTHA) KRAKOWER, CECIL A, UNIVERSITY OF ILLINOIS. 1853 W
POLK ST. CHICAGO. ILL. Antigens related to graft rejection (rabbits,
rats).
R01HL-01648-3I (HEM) BRINKHOUS, KENNETH M, UNIVERSITY OF NORTH
CAROLINA. DEPT OF PATHOLOGY. CHAPEL HILL. N C. Blood coagulation
and hemophilia (dogs, swine).
R01HL-0166I-27 (HEM) RATNOFF, OSCAR D, UNIV HOSPITALS OF CLEVELAND.
DEPARTMENT OF MEDICINE. CLEVELAND. OHIO. Hemostatic
mechanisms (human).
R0IHL-01662-2S (BBCA) SCHERAGA, HAROLD A, CORNELL UNIVERSITY. DE
PARTMENT OF CHEMISTRY. ITHACA. N Y. Equilibria in the fibrinogen-
fibrin conversion (human, cattle).
R01HL-01 755-25 (HED) ASSALI, NICHOLAS S, UNIVERSITY OF CALIFORNIA. 405
HILGARD AVENUE. LOS ANGELES. CALIF. Fetal and neonatal car-
diovascular function (sheep).
ROIHL-01 770-26 (CBY) PEASE, DANIEL C, UNIVERSITY OF CALIFORNIA. 405 HIL
CARD AVENUE, LOS ANGELES. CALIF. Structural aspects of lung sur-
factant system (rats).
ROIHl-01 803-23 (PTHA) BECKER, CARL G, CORNELL UNIVERSITY. 1300 YORK
AVENUE. NEW YORK. N Y. Arteriosclerosis, glomerulonephritis, rheu-
matic fever.
R01HL-OI803-
ROIHL-01803
R01HL-0IB03
ROIHL-01803
ROlHL-01803-
ROIHL-01803
ROIHl-01803
ROIHl-01803
ROIHL-01803
R01HL-01803-
R01HL-01803-
ROIHL-01803'
ROIHL-01803.
ROIHL-01 81 3
ROIHL-01 974
R01HL-0I979-
R01HL-02033
R01HL-02063
R01HL-022I2-
R01HL-02228
R01HL-02254
ROIHL-02262-
ROIHl-02334-
R01HL-02363
R01HL-02477
R01HL-02493-
R01HL-02558
R01HL-02751
R01HL-02799
R01HL-02835-
R01HL-02888
R01HL-02942
R01HL-02953-
ROIHL-02965-
R01HL-02986
PROJECT NUMBER AND INVESTIGATOR ADDRESS
23 0001 (PTHA) BECKER, CARL O. Arterioicleroni. glomeru
loncphrilii. rheumatic fever Post »tr«plococc»l glomerulonephrrln
(rabbit)
23 0005 (PTHA) MINICK, C RICHARD. Artecioictoroiu. glomeru
lonephiitis. rheumatic (ever Immunologic and dietary lyniriy in the
pathogenesis ol atherosclerosis (rabbits)
-23 0010 (PTHA) ALONSO, DANIEL R. ArleriojcleroJU. gtomeru
lonephritis. rheumatic (ever Atherosclerosis induction Graft reiection
and hypercholesterolemia (rabbits)
-23 0011 (PTHA) BECKER, CARL O. ArteriOiclerosis. glomeru
lonephritis. rheumatic fever Immunopathologic consequencei of
cigarette smoking (human, rabbits, plants)
-23 0014 (PTHA) MINICK, C RICHARD. Arleriosclefosii. glomeru
lonephritis. rheumatic fever Regenerated endothelium on lipid accu-
mulation in arterial wall (rabbit)
23 0015 (PTHA) MINICK, C RICHARD. Arteriosclerosis, glomeru
lonephritis. rheumatic fever Immunologic endothelial in)ur> and lipid
diet atherosclerosis (rabbits, monkey)
23 0016 (PTHA) SENTERFIT, B LAURENCE. ArteriosclerosiJ.
glomerulonephritis, rheumatic fever Synthesis of basement membrane
collagen by endothelial cells (human)
•23 0017 (PTHA) BECKER, CARL G. Arteriosclerosis, glomeru
lonephritis. rheumatic fever -Contractile and relaxing proteins of blood
vessels and platelets (mammals, human).
-23 0018 (PTHA) BECKER, CARL G. Arteriosclerosis, glomeru-
lonephritis, rheumatic fever-Fetal immunization in pathogenesis of
glomerulonephritis in adult (rabbit)
23 0019 (PTHA) MURPHY, GEORGE E. Arteriosclerosis, glomeru
lonephritis. rheumatic fever-PathogenesJs of rheumatic heart disease
(rabbit).
23 0020 (PTHA) MINICK, RICHARD C. Arteriosclerosis, glomeru-
lonephritis, rheumatic fever Virus induced arterosclerosis (chickens),
23 0021 (PTHA) BECKER, CARL G. Arteriosclerosis, glomeru-
lonephritis, rheumatic fever-Induction of IgE antibodies to antigen
from tobacco and cigarette smoke (rabbits).
■23 0022 (PTHA) BECKER, CARL G. Arteriosclerosis, glomeru-
lonephritis, rheumatic fever-Cardiac and pulmonary anaphylaxis in-
duced by tobacco glycoprotein (rabbits).
.25 (PHRA) HAUGAARD, NIELS, DEPARTMENT OF PHARMACOLOGY.
36TH & HAMILTON WALK. PHILADELPHIA. PA Regulation of metabolism
by drugs and hormones (rats).
-24 (PHY) POST, ROBERT L, VANDERBILT UNIVERSITY. DEPARTMENT
OF PHYSIOLOGY. NASHVILLE. TENN. Ion-pump in the erythrocyte
(rabbits, guinea pigs).
22 (PTHA) SNYDER, ROBERT I, ZOOLOGICAL SOC OF PHILADELPHIA.
34TH ST AND GIRARD AVENUE. PHILADELPHIA. PA. Arteriosclerosis in
zoo animals on controlled diets (animals).
23 (MET) TREADWEIL, CARLETON R, GEORGE WASHINGTON
UNIVERSITY. 901 23RD STREET. N W, WASHINGTON. D C. Regulation of
cholesterol esters in blood and tissues (rat. cattle, human).
.23 (MBY) MARINETTI, GUlOO V, UNIVERSITY OF ROCHESTER MED
CT. 260 CRITTENDEN BOULEVARD. ROCHESTER. N Y. Biochemistry and
function of lipids and cell membranes (human, yeast, animals).
23 (SSS) LORANO, LASZLO, NORTHWESTERN UNIVERSITY. BIOCHEM
& MOLECULAR BIO DEPT. EVANSTON. ILL. Coagulation of blood
(human).
.24 (PHY) SCHMIDT-NIELSEN, KNUT, DUKE UNIVERSITY. DEPART-
MENT OF ZOOLOGY. DURHAM. N C. Respiration, circulation, and heat
regulation in exercise (bird, mammals).
■23 (HEM) LEWIS, JESSICA H, UNIVERSITY OF PIHSBURGH. DEPART-
MENT OF MEDICINE. PITTSBURGH, PA. Blood coagulation and hemorr-
hagic disease (human, animals).
.23 (HEM) REEVE, E BASIL, UNIVERSITY OF COLORADO. 4200 EAST
NINTH AVENUE. DENVER. COLO. Mechanisms regulating plasma
proteins and solutes (human, dogs).
.23 (GMB) GOTTSCHAIK, CARL W, UNIVERSITY OF NORTH
CAROLINA. DEPARTMENT OF MEDICINE. CHAPEL HILL. N C. Micropunc-
ture study of kidney function (rats, animals).
■20 (SGYA) SCHLOERB, PAUL R, UNIVERSITY OF KANSAS. 39TH &
RAINBOW. KANSAS CITY. KANS. Kinetics of water and electrolytes in
shock (dogs. rats).
.23 (PC) BLOCH, KONRAD E, HARVARD UNIVERSITY. 12 OXFORD
STREET. CAMBRIDGE. MASS. Biosynthesis and function of lipids
(microorganisms, rats).
-22 (CVB) BARGER, A CLIFFORD, HARVARD MEDICAL SCHOOL. 25
SHATTUCK STREET. BOSTON. MASS. Kidney function in experimental
heart failure (dogs. rats).
-22 (BIO) SCHROEDER, WALTER A, CALIFORNIA INST OF TECHNOLO-
GY. 1201 E CALIFORNIA BLVD. PASADENA. CALIF. Structure-function
relationships in the heme proteins (human, cattle).
-21 (PC) PETERS, THEODORE, JR, MARY IMOGENE BASSETT
HOSPITAL. ATWELL ROAD. COOPERSTOWN. N Y. Function and metabol-
ism of serum albumin (mammals, fish, amphibians).
22 (HEM) CHARACHE, SAMUEL, JOHNS HOPKINS HOSPITAL, DE-
PARTMENT OF MEDICINE. BALTIMORE, MD. Abnormal hemoglobins
(human).
21 (PHRA) ROSS, CHARLES R, S U N Y ■ UPSTATE MED CTR. 750 E
ADAMS STREET. SYRACUSE, N Y. Renal transport carrier for organic
compounds (dogs, rats).
-22 (PHY) TENNEY, STEPHEN M, DARTMOUTH MEDICAL SCHOOL,
DEPARTMENT OF PHYSIOLOGY, HANOVER, N H. Interrelationships of cir-
culation and respiration.
-22 (PC) BERENSON, GERALD S, LOUISIANA STATE UNIVERSITY.
1542 TULANE AVENUE. NEW ORLEANS. LA, Biochemistry of car-
diovascular connective tissue (human, cattle, primates).
17 (PHRA) MORAN, NEIL C, EMORY UNIVERSITY, DEPARTMENT OF
PHARMACOLOGY. ATLANTA. GA. Autonomic and cardiovascular phar-
macology (rats, rabbits, dogs, guinea pigs).
22 (MET) EDER, HOWARD A, ALBERT EINSTEIN COLL OF MED. 1300
MORRIS PARK AVENUE. BRONX. N Y. Metabolism of plasma
lipoproteins (rats, chickens, human).
21 (PTHA) SPARGO, BENJAMIN H, UNIVERSITY OF CHICAGO, 950
EAST 59TH STREET. CHICAGO. ILL. Zonal renal change with potassium
deficiency (rats, human).
PROJECT NUMBER AND INVESTIGATOR ADDRESS
P01HL-03I74.23 (HIBB) BENDITT, EARl P, UNIVERSITY OF WASHINGTON
PATHOLOGY DEPARTMENT. SEATTLE. WASH. Mechanisms of acute
vascular reaction to injury,
POlHl-03 174-23 0001 (HLBB) SCHWARTZ, STEPHEN M. Mechanisms of acute
vascular reaction to injury-Response of the vascular intima to injury
(human, rats).
PO I HL-03 174-23 0002 (HLBB) ERIKSEN, NILS. Mechanisms of acute vascular
reaction to injuiy-Chemical structure, pathological significance of
amyloid substance (human, mice).
POIHl-031 74-23 0005 (HLBB) STRIKER. GARY E. Mechanisms of acute vascular
reaction to injury-Renal small vessel dideasc -Cell and matrix
response (human, mice).
POlHl-031 74-23 0006 (HLBB) BENDITT, EARL P. Mechanisms of acute vascular
reaction to injury-Atherosclerotic plaque studies using mosaic analy-
sis (human).
POIHL-031 74-23 0007 (HLBB) VRACKO, RUDOLF. Mechanisms of acute vascu-
lar reaction to injury-Healing of injured myocardium-Basal lamina
scaffold (human, rats, dogs).
POIHL-031 74-23 0009 (HLBB) LAGUNOFF, DAVID. Mechanisms of acute vascu
lar reaction to injury-Mast cell lipid interaction (human, rats)
POIHL-031 74-23 0010 (HLBB) KOCAN, RICHARD M. Mechanisms of acute
vascular reaction to injury -Search for mutagens in the human blood
(bacteria, animals).
POIHl-03 174-23 0011 (HLBB) JUCHAU, MONT R. Mechanisms of acute vascu
lar reaction to injury -Mutagen metabolism by artery wall In etiology of
atherosclerosis (human, animals).
POIHL-03 174-23 0012 (HLBB) MOSS, NED. Mechanisms of acute vascular reac-
tion to injury-Human atherosclerotic plaque in organ culture
P01HL-03I74-23 0013 (HLBB) CHI, EMIL Y. Mechanisms of acute vascular reac
tion to injury-Surface morphology of the aorta in normal and injured
states (rats, rabbits).
ROIHl-03180-21 (SGYB) LEEDS, SANFORD E, MT ZION HOSPITAL & MEDICAL
CTR. POST OFFICE BOX 7921. SAN FRANCISCO, CALIF. Relation of
lymphatics to cardiopulmonary function (dogs).
R01HL-03181-21 (SGYA) SCHENK. WORTHINGTON G, JR, SURGICAL
RESEARCH UBORATORIES, 462 GRIDER STREET, BUFFALO, N Y.
Hemodynamics as applied to surgical problems.
R01HL-03181-21 0020 (SGYA) SCHENK, WORTHINGTON G, JR. Hemodynam
ics as applied to surgical problems-Blood flov» measurement-Cardiac
output and regional flows (dogs).
R01HL-03181-21 0025 (SGYA) SCHENK, WORTHINGTON G, JR. Hemodynam-
ics as applied to surgical problems-Vascular stenosis (dogs)
R01HL-03181.21 0027 (SGYA) SCHENK, WORTHINGTON G, JR. Hemodynam
ics as applied to surgical problems-Hemodynamic studies of the Gl
tract (dogs).
ROIHl-031 81-21 0028 (SGYA) SCHENK, WORTHINGTON G, JR. Hemodynam
ics as applied to surgical problems-Extra-renal factors in the hyper-
tension of coarctation (dog).
R01HL-03181-21 0029 (SGYA) SCHENK, WORTHINGTON G, JR. Hemodynam
ics as applied to surgical problcms-lndocyanine green clearance for
estimation of hepatic blood flow (human).
ROIHl.03290-22 (PHY) HONIG, CARL R, UNIVERSITY OF ROCHESTER. 601 ELM
WOOD AVENUE, ROCHESTER, N Y. Controls of cardiac and vascular
smooth muscles (cats, rats, dogs).
R01HL-03299-21 (NTN) KRITCHEVSKY, DAVID, WISTAR INSTITUTE, 36TH AND
SPRUCE STREETS, PHILADELPHIA, PA. Dietary effects on cholesterol
metabolism (rats, rabbits).
R01HL-03303-21 (CVA) WALKER, W GORDON, JOHNS HOPKINS HOSPITAL 601
NORTH BROADWAY. BALTIMORE. MO. Factors regulating electrolyte
excretion by the kidney (human, dogs).
ROIHl-03341-22 (EDC) HAMES, CURTIS G, 2 NORTH NEWTON STREET, CLAXTON,
GA. Epidemiology of atherosclerosis in Evans Co Georgia
R01HL-033S7-21 (HEM) GORDON, ALBERT S. NEW YORK UNIVERSITY 100
WASHINGTON SQUARE EAST, NEW YORK, N Y. Humoral control of blood
cell formation and release (rats, mice).
ROIHl-03424-21 (HEM) SEEGERS, WAITER H, WAYNE STATE UNIVERSITY, 540 E
CANFIELD, DETROIT, MICH. Formation and properties of prothrombin
derivatives (human, animals).
R01HL-03429-18 (EDC) ROSENMAN, RAY H, MOUNT ZION HOSP & MED CENTER
POST OFFICE BOX 7921, SAN FRANCISCO, CALIF. Central nervous
system and coronary heart disease (human).
ROIHl-03734-18 (MET) HASHIMOTO, SAM, VA WADSWORTH HOSPITAL CENTER
BLDG 118, ROOM 120. LOS ANGELES. CALIF. Metabolism of arterial tis-
sue in atherosclerosis (rabbits).
R01H1.039I9-20 (ALY) MC CARTY, MACLYN, ROCKEFELLER UNIVERSITY 1230
YORK AVENUE. NEW YORK, N Y, The cell suface of streptococci (rats,
human),
R01HL-O3941-I8 (CVA) GREISS, FRANK C, JR, BOWMAN GRAY SCHOOL OF
MEDICINE, DEPT OF OBSTETRICS & GYNECOLOG, WINSTON-SALEM, N C.
Uterine blood flow and changes in pregnancy (sheep),
R0IHL-04300-20 (PTHA) JONES, DAVID B, S U N Y - UPSTATE MED CTR 750
EAST ADAMS STREET, SYRACUSE, N Y. Fine structure of diseased
glomeruli (human, rats, dogs).
R0IHL.04366-I9 (SSS) ROBBINS, KENNETH C, MICHAEL REESE RES FOUNDA-
TION. 530 EAST 31ST STREET, CHICAGO, ILL, Plasminogen-Activation
and structure-function relations (mammals, birds),
ROIHL.04442-20 (PC) RABINOWITZ, MURRAY, UNIVERSITY OF CHICAGO, 950
EAST 59TH STREET, CHICAGO, ILL. Mitochondrial assembly and repli-
cation (fungi, wheat).
ROIHL-04457.20 (PHY) FORSTER, ROY P, DARTMOUTH COLLEGE, DEPT OF BIOLOG-
ICAL SCIENCES, HANOVER, N H Cellular aspects of active transport
(fish, rabbits, anurans, turtles)
R01HL-04512-19 (CBY) WISSIG, STEVEN I, UNIVERSITY OF CALIFORNIA PARNAS-
SUS AVE, DEPT OF ANATOMY, SAN FRANCISCO, CALIF, Ultrastructural
studies of capillary permeability (rats, mice),
R01HL-046I2-20 (HEM) ERSIEV, ALLAN J, CARDE2A FDN/HEMATOLOGIC RES,
1015 WALNUT ST, CURTIS BLDG, PHILADELPHIA, PA, Feedback between
red cell production and oxygen transport (rabbits, rats).
ROIHl.04651-19 (SGYB) GLENN, WILLIAM W, YALE UNIVERSITY, 333 CEDAR
STREET, NEW HAVEN, CONN, Remote stimulation by radio-frequency
transmission (dogs, human),
POIHl.04664-18 (HEP) WOOD, EARl H, MAYO FOUNDATION, 200 FIRST STREET
SOUTHWEST, ROCHESTER, MINN. Cardiovascular and lung dynamics
POIHl-04664.18 0001 (HEP) WOOD, EARL H. Cardiovascular and lung dynam-
ics-X-ray projection image videodensitometry (dogs).
524
POIHL-04664.18 0002 (HEP) WOOD, EARL H. Cardiovascular and lung dynam-
ics-X-ray cross section imaging of organs (dogs).
P01HL-04664-18 0003 (HEP) WOOD, EARl H. Cardiovascular and lung dynam-
ics-X-ray projection image videometry (human, dogs).
POIHl-04664-18 0004 (HEP) WOOD, EARL H. Cardiovascular and lung dynam-
ics-X-ray cross section imaging of the circulation (dogs).
POIHL-04664.18 0005 (HEP) WOOD, EARl H. Cardiovascular and lung dynam-
ics-Applications of current research, equipment and techniques.
POIHL-04664.18 0006 (HEP) WOOD, EARl H. Cardiovascular and lung dynam-
ics-Cross section imaging of organ functions using emitted radiation
(dogs).
POIHl.04664.18 0007 (HEP) WOOD, EARl H. Cardiovascular and lung dynam
ics-Development and application of ultrasound imaging techniques.
POIHl-04664-18 0008 (HEP) WOOD, EARL H. Cardiovascular and lung dynam-
ics-Micrographic video imaging technique.
POIHl-04664-18 0009 (HEP) WOOD, EARl H. Cardiovascular and lung dynam-
ics-Biological signal and image processing techniques (dogs).
POIHl-04664-18 0010 (HEP) WOOD, EARL H. Cardiovascular and lung dynam-
ics-Left ventricular dynamics (human).
POIHL-04664-18 0011 (HEP) URIE, PAUL M. Cardiovascular and lung dynamics-
Detection of abnormal segments of the human ventricle by measure
of asynergy.
POIHl.04664-18 0012 (HEP) URIE, PAUL M. Cardiovascular and lung dynamics-
Quantitative single plane left ventricular angiography (human).
POIHL-04664-18 0013 (HEP) MARSHALL, HIRAM W. Cardiovascular and lung
dynamics -Ventricular function in coronary disease using NTG and ven-
triculograms (human).
POIHL.04664.18 0014 (HEP) CLAYTON. PAUL D. Cardiovascular and lung
dynamics-Clinical application of computer analysis of ventricular wall
motion.
POIHL.04664.18 0015 (HEP) CLAYTON, PAUL D. Cardiovascular and lung
dynamics -Computer system for the cardiovascular laboratory
POIHl-04664.18 0016 (HEP) BARRETT, WILLIAM A. Cardiovascular and lung
dynamics-Computerized roentgenographic determination of total lung
capacity.
ROIHL.04666.19 (CVA) ESCHER, DORIS J, MONTEFIORE HOSPITAL & MED CTR,
111 EAST 210TH STREET. BRONX, N Y Artificially paced hearts-
Technology, physiology (human, dogs).
ROIHl.04697-17 (TEC) KEYS, ANCEl, UNIVERSITY OF MINNESOTA, STADIUM GATE
27, MINNEAPOLIS, MINN. International heart disease epidemiology
(human).
ROIHL.05062.18 (MET) BAILEY, J MARTYN, DEPARTMENT OF BIOCHEMISTRY
2300 EYE STREET, N W, WASHINGTON, D C. Lipid metabolism in cul-
tured cells (human, rats, rabbits).
R01H1.05I68-I9 (HEM) HUISMAN, TITUS H, MEDICAL COLLEGE OF GEORGIA
1459 GWINNEH ST, AUGUSTA, GA. Inhomogencity of hemoglobin types
(human).
R01HL-05209.18 (NTN) KRITCHEVSKY, DAVID, WISTAR INSTITUTE, 36TH AND
SPRUCE STREETS, PHILADELPHIA. PA. Lipid metabolism (monkeys)
R01HI.05351.I8 (HEM) MOHN, JAMES F, S U N Y - AT BUFFALO, 233 SHERMAN
HALL, IMMUNOL CTR , BUFFALO, N Y. Blood group antigens and an-
tibodies (human, rabbits, sheep).
ROIHl.05360-19 (MET) COOPER, ALLEN D, STANFORD UNIVERSITY, MEDICINE DE-
PARTMENT, STANFORD, CALIF. Cholesterol biosynthesis and its control
in liver (rats).
R01HL.05556.I9 (BBCA) GURD, FRANK R, INDIANA UNIVERSITY, DEPARTMENT OF
CHEMISTRY, BLOOMINGTON, IND. Proteins, lipoproteins -Structure and
reactivity (chicken, human, diving mammals).
ROIHl.05694-20 (PTHA) EDWARDS, JESSE E, UNITED HOSPS-MILLER DIVISION
125 W COLLEGE AVENUE, ST PAUL. MINN. Functional pathology of car-
diovascular disease (human).
R01H1.0S79I-18 (HEM) BENESCH, RUTH E, COLUMBIA UNIVERSITY 630 WEST
168TH STREET, NEW YORK, N Y. Structure and function in
hemoglobins (human).
R01Hl.05806.18 (CVB) lUCCHESI, BENEDICT R, UNIVERSITY OF MICHIGAN
PHARMACOLOGY DEPARTMENT. ANN ARBOR, MICH. Analysis of antiarr-
hythmic agents (dogs, rabbits).
ROIHl-05875-18 (CVB) HACKEl, DONALD B, DUKE UNIVERSITY, MEDICAL
CENTER, DURHAM, N C. Pathologic metabolic and physiologic studies
of heart (human, dogs, cats).
ROlHl.05883-18 (AFY) SHEPHERD, JOHN T, MAYO FOUNDATION, 200 FIRST
STREET, S W, ROCHESTER, MINN. Reflex control of resistance and
capacitance vessels.
R0IHI-0S883-18 0001 (AFY) SHEPHERD, JOHN T. Reflex control of resistance
and capacitance vessels-Naturally occurring vasoactive substances
and the vascular neuroeffectors (dog)
ROIHl.05883.18 0002 (AFY) SHEPHERD, JOHN T. Reflex control of resistance
and capacitance vessels-Adenosine, adenine nucleotides and vascular
smooth muscle (dog).
R01HL-05883-18 0003 (AFY) SHEPHERD, JOHN T. Reflex control of resistance
and capacitance vessels-Cardiac glycosides and sympathetic nerve
terminals in vascular smooth muscle
ROIHl-05883-18 0004 (AFY) SHEPHERD, JOHN T. Reflex control of resistance
and capacitance vessels-Left ventricular receptors with nonmedul-
lated vagal afferents (cats).
ROIHL-05883-18 0005 (AFY) SHEPHERD, JOHN T. Reflex control of resistance
and capacitance vessels -Differential blockade of medullated and non-
medullated vagal afferents in the cat
ROlHL-05883-18 0006 (AFY) SHEPHERD, JOHN T. Reflex control of resistance
and capacitance vessels-Cardiopulmonary vagal afferents in the con-
scious dog.
R01HL-05883.18 0007 (AFY) SHEPHERD, JOHN T. Reflex control of resistance
and capacitance vesscls-Prostaglandins and skeletal muscle blood
flow (dogs),
ROIHl-05883-18 0008 (AFY) SHEPHERD, JOHN T. Reflex control of resistance
and capacitance vessels -Oxygen consumption of the chronically de-
nervated dog heart.
ROIHl.05949.18 (BBCB) GERGELY, JOHN, BOSTON BIOMEDICAL RES INST 20
STANIFORD STREET, BOSTON, MASS 02114. Biochemistry of muscle
contraction (rats, rabbits).
R01HL-06143.18 (AFY) DONALD, DAVID E. MAYO FOUNDATION. 200 FIRST
STREET SOUTHWEST, ROCHESTER, MINN. Response of the totally de-
nervated heart to exercise (dogs).
R0IHL-06m
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S2S
17 (MIT) AULUPOVIC, PITAH, OKIAHOM* MED RESEARCH FDN.
825 N E 13TH STREET. OKLAHOMA CITY. OKLA Composition and Jliuc
lure ot plasma lipopraltms (human, luikeys, baboons)
IS (MET) AHRiNS, EDWARD H. JR. ROCKEFELLER UNIVERSITY.
66TH STREET & YORK AVfNUf. NEW YORK. N Y Clinical and laboialo
ry sludies in lipid meldbohsm (human, mammals, non human)
.18 (HEM) FINCH, CLEMENT A, UNIVERSITY OF WASHINGTON. DIVI
SION OF HEMATOLOGY. SEAOLE. WASH Kinetic studios o( blood
(human)
.18 (HEP) HAVEL, RICHARD J, UNIVERSITY OF CALIFORNIA. 3RD AND
PARNASSUS. SAN FRANCISCO. CALIF Caidiovasculai lespiialofY
physiology and biochemistry
■ 18 0125 (HEP) RUDOLPH, ABRAHAM M. Cardiovascular respira-
tory physiology and biochemistiv Myocardial (unction in the fetal and
neonatal lamb
-18 0126 (HEP) RUDOLPH, ABRAHAM M. Cardiovascularrespifa
tory physiology and biochemistry Ventricular output, foramen ovale
and ductus arteriosus flows (lambs)
-18 0127 (HEP) HEYMANN, MICHAEL A. Cardiovascular respirato
ry physiology and biochemistry-Experimental congenital cardiac le-
sions in fetal lambs.
18 0128 (HEP) RUDOLPH, ABRAHAM M. Cardiovascular respira
tory physiology and biochemistry Pulmonary circulation in fetal lambs
in utero
18 0129 (HEP) HEYMANN, MICHAEL A. Cardiovascular-respirato
ry physiology and biochemistry -Pulmonary microcirculation in the
tetus and neonate (lambs).
.18 0130 (HEP) HEYMANN, MICHAEL A. Cardiovascular respirato
ry physiology and biochemistry -Ductus artoriosus-Morphological
development (human, lambs),
-18 0131 (HEP) RUDOLPH, ABRAHAM M. Cardiovascular-respira
tory physiology and biochemistry- Fetal heart development and ven-
tricular outflow obstruction (lambs).
-18 0132 (HEP) RUDOLPH, ABRAHAM M. Cardiovascular-respira-
tory physiology and biochemistry-Umbilical-placental circulatory
responses (lambs).
-18 0133 (HEP) CREASY, ROBERT K. Cardiovascular-respiratory
physiology and biochemistry -Decreased uterine blood flow and fetal
development (lambs).
18 0134 (HEP) CREASY, ROBERT K. Cardiovascular-respiratory
physiology and biochemistiy-Placental transfer in growth retarded
fetuses (lambs).
1 0135 (HEP) CREASY, ROBERT K. Cardiovascular-tespiratory
physiology and biochemistry -Beta-adrenergic agents and fetal car-
diovascular dynamics (lambs).
18 0136 (HEP) PHIBBS, RODEHIC. Cardiovascular-respiratory
physiology and biochemistry -Fetal microcirculation in utero (rabbits,
lambs).
18 0143 (HEP) HOFFMAN, JULIEN I. Cardiovascular-respiratory
physiology and biochemistry-Myocardial ischemia (human, dogs,
lambs).
18 0145 (HEP) STAUB, NORMAN C. Cardiovascular-respiratory
physiology and biochemistry-Pulmonary, pleural and systemic
microcirculation (animals).
18 0146 (HEP) SEVERINGHAUS, JOHN W. Cardiovascular
respiratory physiology and biochemistry-Pathogenesis and detection of
hypoxic pulmonary edema (human, animals).
.18 0147 (HEP) SEVERINGHAUS, JOHN W. Cardiovascular
respiratory physiology and biochemistry-Metabolic regulation of
cerebral microcirculation (cats).
-18 0149 (HEP) SIPERSTEIN, MARVIN D. Cardiovascular-respiratory
physiology and biochemistry-Microangiopathy in prediabetic and
diabetic subjects (human).
-18 0150 (HEP) SIPERSTEIN, MARVIN D. Cardiovascular-respiratoiy
physiology and biochemistry-Basement membrane width in non-
diabetic hyperglycemia.
-18 0151 (HEP) SIPERSTEIN, MARVIN D. Cardiovascular-respiratory
physiology and biochemistry-Microangiopathy in diabetic and glucose
intolerant children.
18 0152 (HEP) SIPERSTEIN, MARVIN D. Cardiovascular-respiratory
physiology and biochemistry-Diabetic microangiopathy by organ and
tissue culture (human).
18 0153 (HEP) PARMLEY, WILLIAM W. Cardiovascular-respiratory
physiology and biochemistry-Myocardial mechanics and pharmacology
in isolated papillary muscle (animals).
18 0154 (HEP) PARMLEY, WILLIAM W. Cardiovascular respiratory
physiology and biochemistry-Function and viability of critically
ischemic myocardium (dogs).
.18 0155 (HEP) PARMLEY, WILLIAM W. Cardiovascular-respiratory
physiology and biochemistry-Therapeutic alterations, contractile state
in heart failure.
-18 0156 (HEP) PARMLEY, WILLIAM W. Cardiovascular-respiratory
physiology and biochemistry-Myocardial performance following
revascularization (human).
-18 0157 (HEP) PARMLEY, WILLIAM W. Cardiovascular-respiratory
physiology and biochemistiy-Left ventricle outflow Impedance analysis
(human).
-18 0158 (HEP) RAPAPORT, ELLIOT. Cardiovascular-respiratory
physiology and biochemistry -Load on myocardial contractility (dogs).
-18 0164 (HEP) RAPAPORT, ELLIOT. Cardiovascular-respiratory
physiology and biochemistry-CPK MB isoenzyme concentration to
quantify infarct size (human, animals).
18 0173 (HEP) 80TTS, JEAN. Cardiovascular-respiratory physiology
and biochemistry -Skeletal and cardiac muscle function.
18 0178 (HEP) KUN, ERNEST. Cardiovascular-respiratory physiology
and biochemistry-Biochemical regulation of hypertrophy (rats, rab-
bits). , . ,
18 0179 (HEP) HOLLENBERG, MILTON. Cardiovascular-respiratory
physiology and biochemistiy-Regulation of myocardial cell growth
(rats, chick embryo).
■ 18 0180 (HEP) COLERIDGE, JOHN C G. Cardiovascular-respirato-
ry physiology and biochemistry-Vagal C-fibers and their influence on
visceral and somatic function (animals).
P01Hl-0628S^
P0IHL^062SS
P01HL-06285-
P01HL-06285-
P01HL-06285-
P01HL-06285-
P01HL-06285-
POlHL-06285
POIHL-06285
POIHL-06285
POlHL-06285-18
P01HL-06285-
POIHL-06285-
POIHL-06285
POIHL-06285
POlHl-06285
POlHL-06285-
P01HL-06285-
P01HL-06285-
POlHL-06285
POIHL-06285
POIHL-06285
POIHL-06285
POlHL-06285-
POlHL-06285
P01HL-06285-
P01HL-06296-
P01 H 1-062 96-
P01HL-06296.
P01HL-06296
P01HL-06296-
P01HL-06308-
POIHl-06308-
P01HL-06308
P01HL-06308
P01HL-06308
Cardiovascular-respiratory
counter-current system
PROJECT NUMBER AND INVESTIGATOR ADDRESS
18 0181 (HIP) NAD8L, JAV A. CifdiovHcuUt mpi'ilory phynolo
gy and biochemistry Regulation of rupliition Role ot v»|ui nerve
(dogs)
18 0182 (HEP) MITCHELL. ROBERT A. C»rdiov»Kul»r (eipirelory
physiology and biochemisliy Structure end function of veecular
chomoreceptors (cats, rats)
18 0186 (HEP) MELMON, KENNETH I. Cardiovescultf respirttory
physiology and biochemistry Leukocyte hormone receptors and cyclic
nucleotides (tissue culture)
IB 0188 (HEP) NADEL, JAY A. Cardiovascular respiratory phyiiolo
gy and biochemistry Physiology and pharmacology m regulation of aif
ways hyperirritability (animals)
18 0189 (HEP) NADEL, JAY A. Cardiovascular respiratory physiolo
gy and biochemistry Mucociliary clearance (cats, dogs)
.18 0190 (HEP) NADEL, JAY A. Cardiovascular respiratory physiolo
gy and biochemistry Maximal (airway) flow (human, dogs)
■ 18 0193 (HEP) EDEUAAN. ISIDORE S. Cardiovascular respiratory
physiology and biochemistry-Hormonal regulation of sodium transpo.1
Aldosterone (rats, toads)
-18 0194 (HEP) EDEIAAAN, ISIDORE S. Cardiovascular respiratory
physiology and biochemistry Hormonal regulation of sodium transport-
-RNA synthesis (rats, toads)
-18 0195 (HEP) EDEIMAN, ISIDORE S. Cardiovascular respiratory
physiology and biochemistry- Thyroid thermogenesis and sodium trans-
port (rats).
18 0196 (HEP) EDEUVIAN. ISIDORE S. Cardiovascular respiratory
physiology and biochemistry -Hormonal regulation of sodium transport-
Epithelial cell membranes (toads).
0197 (HEP) RECTOR. FLOYD C. Cardiovascular respiratory
physiology and biochemistry -Microperfusion and micropuncture of
renal tubules (hamsters, desert rats).
18 0198 (HEP) RECTOR. FLOYD C. Cardiovascular respiratory
physiology and biochemistry-Renal tubular secretion of hydrogen ion
(animals).
18 0199 (HEP) RECTOR, FLOYD C. Cardiovascular-respiratory
physiology and biochemistry -Renal tubular reabsorption of sodium
chloride (hamsters, rabbits).
■ 18 0200 (HEP) RECTOR, FLOYD C.
physiology and biochemistry-Medullary
(animals).
-18 0203 (HEP) HAVEL. RICHARD J. Cardiovascular respiratory
physiology and biochemistry-Pathways of lipid transport in the blood
(animals).
-18 0204 (HEP) FELTS. JAMES M. Cardiovascular-respiratory
physiology and biochemistry-Lipoprotein lipase and triglyceride trans-
port in chylomicrons (guinea pig. rat).
18 0205 (HEP) MAYERLE, JOAN A. Cardiovascular-respiratory
physiology and biochemistry-Assimilation of cholesterol in
chylomicrons and VLDL (rabbits).
18 0207 (HEP) SIPERSTEIN, MARVIN O. Cardiovascular-respiratory
physiology and biochemistry-Feedback control of cholesterol synthesis
in non-hepatic tissues (animals).
.18 0208 (HEP) CLEMENTS, JOHN A. Cardiovascular-respiratory
physiology and biochemistry-Composition, properties and turnover of
pulmonary surfactant (human, animals).
■18 0209 (HEP) MASON, ROBERT J. Cardiovascular-respiratory
physiology and biochemistry-Metabolic studies of isolated lung cells
(human, animals).
-18 0210 (HEP) GOERKE, R JON, III. Cardiovascular-respiratoiy
physiology and biochemistry-Physicochemical and enzymatic studies
of lung surfactant (Halobacterium).
-18 0211 (HEP) STOECKENIUS, WALTHER. Cardiovascular-respira-
tory physiology and biochemistry-Purple membrane of Halobacteria.
-18 0212 (HEP) STOECKENIUS, WALTHER. Cardiovascular-respira-
tory physiology and biochemistry-Membrane structure and function-
Gap junction (bovine).
18 0213 (HEP) STOECKENIUS, WALTHER. Cardiovascular-respira-
tory physiology and biochemistry-Membrane structure and function-
Gas vacuole membrane (Halobacterium).
18 0214 (HEP) STOECKENIUS, WALTHER. Cardiovascular-respira-
tory physiology and biochemistry-Membrane structure and function-EM
of macromolecules.
18 0215 (HEP) YANG, JEN TSI. Cardiovascular-respiratory physiolo-
gy and biochemistry-Conformation of biopolymers.
18 (HEPA) MITCHELL, JERE H, UNIVERSITY OF TEXAS, 5323 HARRY
HINES BLVD. DALLAS. TEX. Cardiovascular and pulmonary adaptation
to stress.
■ 18 0002 (HEPA) JOHNSON. ROBERT L. Cardiovascular and pul-
monary adaptation to stress-Respiratory muscle blood flow,
mechanics and metabolism (human, dog).
-18 0003 (HEPA) BLOMQVIST. GUNNAR. Cardiovascular and pul-
monary adaptation to stress-Human exercise studies (human, dogs).
18 0005 (HEPA) WILDENTHAL, KERN. Cardiovascular and pulmo-
nary adaptation to stress-Regulation of ventricular performance
(animals).
18 0007 (HEPA) MITCHELL, JERE H. Cardiovascular and pulmona-
ry adaptation to stress-Cardiovascular control during isometric exer-
cise (cats).
18 (HEPA) FISCH, CHARLES, INDIANA UNIVERSITY. 1100 WEST
MICHIGAN STREET. INDIANAPOLIS, IND. Mechanisms and therapy of
circulatory disease.
18 0010 (HEPA) MCHENRY, PAUL L. Mechanisms and therapy of
circulatory disease-Ventricular arrhythmias during exercise to CHO
and myocardial ischemia (human).
18 0011 (HEPA) KNOEBEL, SUZANNE B. Mechanisms and
therapy of circulatory disease-Blood flow and electrical dysfunction in
ventricular arrhythmia (human).
■ 18 0012 (HEPA) FEIGENBAUM, HARVEY. Mechanisms and
therapy of circulatory disease-Echocardiographic evaluation of
hemodynamics of arrhythmia (human).
-18 0025 (HEPA) BESCH. HENRY R, JR. Mechanisms and therapy
of circulatory disease-Subcellular calcium pools in the genesis of arr-
hythmias (dogs).
PROJECT NUMBER AND INVESTIGATOR ADDRESS
526
P01Hl^6308
P01HL-06308-
POIHl-06308
POIHl-06308
POIHL-06308
POIHL-06308
POIHL-06308-
POIHL-06308
POIHL-06308
PO1HL-06312
P01HL-06312.
POIHL-06312.
P01HL-063I2-
P0IHL-06312-
P01HL-06312
P01HL-06312
P0)HL-063I2
P01HL-063I2-
POIHl-06312-
P01HL-063I2.
P01HL-06312-
P01HL-06312-
POIHL-06312-
POIHL-06312
POIHL-06312
POIHL-06312
POIHL-06312.
POIHL-06312.
POIHL-06312-
POlHL-06312-
P01HL-O63I2
POIHL-06312.
POIHL-06312-
POIHL-06312-
POIHL-06312-
P0IHL-063I2-
P01HL-063I2-
POIHL-06312-
P0IHL^>63I2-
P01HL-06312
P01HL-06314
P01HU06314.
P01HL-063I4-
P01HL-063I4.
18 0029 (HEPA) ZIPES, DOUGLAS P. Mechanisms and therapy of
circulatory disease-Characterization of the patient with recurrent ven-
tricular arrhythmias.
18 0035 (HEPA) BAILEY, JOHN C. Mechanisms and therapy of cir-
culatory disease-Mechanisms for electrophysiological changes in
myocardial infarction (dogs).
18 0037 (HEPA) ZIPES, DOUGLAS P. Mechanisms and therapy of
circulatory disease-ElectrophysJology, blood flow, and ANS in ventricu-
lar fibrillation (dogs).
18 0038 (HEPA) ZIPES, DOUGLAS P. Mechanisms and therapy of
circulatory disease-Electrophysiology of ventricuair arrhythmias as-
sociated with ischemia (dogs).
18 0039 (HEPA) WATANABE, AUGUST M. Mechanisms and
therapy of circulatory disease-ANS in regulation of electrophysiology-
Role of cyclic nulceotides (animals).
18 0040 (HEPA) WILLIAMS, ERIC S. Mechanisms and therapy of
circulatory disease -Metabolism and fatty acid utilization -Heart electri-
cal stability (rats. dogs).
18 0042 (HEPA) CORYA, BETTY C. Mechanisms and therapy of
circulatory disease-Echocardiographic assessment of arrhythmias-
Myocardial tissue type (human, dogs).
■18 0043 (HEPA) DILLON, JAMES C. Mechanisms and therapy of
circulatory disease-Exercise and echocardiographic examining
techniques (human).
•18 0044 (HEPA) WEVMAN, ARTHUR E. Mechanisms and therapy
of circulatory disease -Echocardiography to determine site of ectopic
impulse formation (human, dogs).
17 (HEP) WIIUMAN. VALLEE L, ST LOUIS UNIVERSITY. 1325 SOUTH
GRAND BLVD. ST LOUIS, MO. Surgical cardiology
17 0013 (HEP) KAISER, GEORGE C. Surgical cardiology -Aortocoro-
nary vein bypass grafting (human).
-17 0015 (HEP) BARNER, HENDRICK B. Surgical cardiology-Inter-
nal mammary artery versus saphenous vein for coronary artery bypass
(human).
-17 0016 (HEP) BARNER, HENDRICK B. Surgical cardiology-Effect
of hydralazine on infarct size following coronary occlusion (human)
•17 0017 (HEP) WILUWAN, VALLEE L. Surgical cardiology-Cardiac
transplantation (human).
•17 0018 (HEP) WILUWAN, VALLEE L. Surgical cardiology-Cardiac
transplantation growth (calves).
17 0021 (HEP) WILIMAN, VALLEE L. Surgical cardiology- Cardiac
transplantation-Effect of immunosuppression on atherogenesis
(monkeys).
17 0022 (HEP) WILUWAN, VALLEE L. Surgical cardiology -Cardiac
transplant-Experimental simultaneous heart and kidney transplant
(dogs).
17 0023 (HEP) WILLMAN, VALLEE L. Surgical cardiology-Effect of
denervation on atherosclerosis.
17 0025 (HEP) WILLMAN, VALLEE L. Surgical cardiology-Effect of
denervation on arrhythmias and function with coronary occlusion
(dogs).
-17 0028 (HEP) WILLMAN, VALLEE I. Surgical cardiology -Coronary
flow in the transplanted denervated heart (dogs)
-IT^ 0029 (HEP) WILIMAN, VALLEE I. Surgical cardiology-Cardiac
lymphatics in the transplanted heart (dogs).
-17 0030 (HEP) PIETRAFITTA, J. Surgical cardiology -Total artificial
heart (calves).
■17 0032 (HEP) JELLINEK, MAX. Surgical cardiology-Preservation of
the heart by perfusion (dogs).
■17 0033 (HEP) MENZ, LEO. Surgical cardiology -Studies in
cryoprescrvations (rats).
•17 0034 (HEP) JELLINEK, MAX. Surgical cardiology -Metabolic fac-
tors in cardiac function-Creatine phosphate depletion (animals)
■17 0036 (HEP) WILUVIAN, VALLEE I. Surgical cardiology -Experi-
mental studies of cardiac compliance (dogs)
17 0039 (HEP) WILIMAN, VALLEE L. Surgical cardiology-Cardiac
transplantation-Biopsy correlates of rejection
17 0040 (HEP) PENNINGTON, G. Surgical cardiology -Left ventri-
cle assist (dogs).
17 0041 (HEP) PENNINGTON, G. Surgical cardiology -A ser-
vomechanism for left ventricular assist (human, dogs, sheep)
-17 0042 (HEP) PENNINGTON, G. Surgical cardiology -Right ven-
tricular assist device (sheep)
-17 0043 (HEP) PENNINGTON, G. Surgical cardiology -The cylindri-
cal ventricular assist device (dogs).
■17 0044 (HEP) BARNER, HENDRICK B. Surgical cardiology-The
limits of topical cardiac hypothermia with ice chips (rats)
■17 0046 (HEP) JELLINEK, MAX. Surgical cardiology-The relation-
ship of prostaglandins to heart disease.
17 0047 (HEP) PENNINGTON, G. Surgical cardiology -Myocardial
extravascular water (dogs).
-17 0048 (HEP) LAKS, HILLEL. Surgical cardiology -Use of an ad-
justable pulmonary artery band (dogs).
■17 0049 (HEP) PENNINGTON, G. Surgical cardiology-Long-term
pulmonary vascular resistance (human).
■17 0050 (HEP) PENNINGTON, G. Surgical cardiology-Prevention
of pericardial and pleural adhesions by silicone oil (dogs)
17 0051 (HEP) BARNER, HENDRICK B. Surgical cardiology-Diu-
retic therapy on myocardial electrolyte composition and water content
(human).
17 0052 (HEP) BARNER, HENDRICK B. Surgical cardiology -Assay
of metabolic variables of rat heart.
-17 0053 (HEP) KAISER, GEORGE C. Surgical cardiology-Enzyme
pattern following cardiac surgery (human).
-17 (HEP) VERNIER, ROBERT I, UNIVERSITY OF MINNESOTA, BOX
491 MAYO HOSPITAL, MINNEAPOLIS, MINN. Immunologic mechanisms
in cardiovascular disease.
•17 0046 (HEP) GRAY, BEULAH H. Immunologic mechanisms in
cardiovascular disease-Mediators of immune injury (human mice)
■17 0047 (HEP) WHITE, JAMES G. Immunologic mechanisms in
cardiovascular disease-Role of intravascular coagulation (human
animals).
17 0048 (HEP) VERNIER, ROBERT L. Immunologic mechanisms in
cardiovascular disease-Pathogenesis of glomerulonephritis (rats
mice).
POlHL-06314-17 0050 (HEP) ROSENBERG. ANDREAS. Immunologic
mechanisms in cardiovascular disease -Physiologic changes in
lymphocytes (human, mice).
17 0051 (HEP) WOODWARD, CLARE K. Immunologic mechanisms
in cardiovascular disease-Conformational studies of phospholipid
membranes and proteins.
17 0052 (HEP) ESTENSEN, RICHARD D. Immunologic mechanisms
in cardiovascular disease-Role of cyclic nucleotides in neutrophil
function (human).
17 0053 (HEP) GOLDBERG, NELSON. Immunologic mechanisms
In cardiovascular disease-Cellular functions controlled by cyclic GMP
(human, mice, guinea pigs).
17 0054 (HEP) SHERIDAN, JUDSON D. Immunologic mechanisms
in cardiovascular disease-Physiology of cell communications (mice
frogs, guinea pigs).
■17 0055 (HEP) SHEPPARD. JOHN. Immunologic mechanisms in
cardiovascular disease-Genetics and cell biology.
17 0057 (HEP) GRAY, ERNEST D. Immunologic mechanisms in
cardiovascular disease -Antigens in cardiovascular disease (human)
17 0059 (HEP) GREENBERG, LEONARD J. Immunologic
mechanisms in cardiovascular disease-lmmunogenetic response to
streptococcal antigens in man.
17 0060 (HEP) FERRIERI, PATRICIA. Immunologic mechanisms in
cardiovascular disease -Strept antigens and infections in cardiovascu-
lar complications (human, animals).
-17 0061 (HEP) BALFOUR, H H, JR. Immunologic mechanisms in
cardiovascular disease-Role of viruses in cardiovascular and renal
disease (human, mice).
■17 0062 (HEP) MICHAEL, ALFRED F. Immunologic mechanisms in
cardiovascular disease-lmraunologic renal vascular disease (human
animals).
•17 0063 (HEP) FISH, ALFRED J. Immunologic mechanisms in car-
diovascular disease-Glomerular cells in tissue culture (human)
■17 0064 (HEP) BROWN, DAVID M. Immunologic mechanisms in
cardiovascular disease -Diabetic vascular disease (human, rats mice)
17 0065 (HEP) AMPLATZ, KURT. Immunologic mechanisms in car-
diovascular disease-Transplantation biology and clinical transplanta-
tion.
17 0066 (HEP) DOUGLAS, STEVEN D. Immunologic mechanisms
in cardiovascular disease -Sensitization, cell-mediated cytotoxicity, role
of lymphocytes (human, mice).
17 0067 (HEP) SCHMIDTKE, JON R. Immunologic mechanisms in
cardiovascular disease-Mitogenic and antigenic activation of lympho-
cyte sub-populations.
17 (HEP) GRAHAM, JOHN B, UNIVERSITY OF NORTH CAROLINA
SCHOOL OF MEDICINE, CHAPEL HILL. N C. Hemostasis research pro-
gram project.
-17 0005 (HEP) WAGNER, ROBERT H. Hemostasis research pro
gram project-Purification of plasma antihemophilic factor (human)
-17 0015 (HEP) GRAHAM, JOHN B. Hemostasis research program
proiect-Genetics (human).
■17 0018 (HEP) ROBERTS, HAROLD R. Hemostasis research pro-
gram project-Varients of factors IX (human, cattle)
■17 0019 (HEP) DALLDORF, FREDERIC G. Hemostasis research pro-
gram project-Microcirculation (human, rats, rabbits)
•17 0020 (HEP) MCDONAGH, RICHARD P. Hemostasis research
program project-Structure and function of coagulant venom
proteases.
17 (HEP) COTRAN, RAMZI S, PETER BENT BRIGHAM HOSPITAL 721
HUNTINGTON AVENUE. BOSTON, MASS. Cardiopulmonary and 'renal
pathology research center.
17 0001 (HEP) BUSCH, GEORGE J. Cardiopulmonary and renal
pathology research center-The humoral and cellular mechanisms of
allograft rejection (monkeys).
-17 0004 (HEP) POLET, HERMAN. Cardiopulmonaiy and renal
pathology research center-Lymphocytes in graft rejection and immune
surveillance (human).
-17 0006 (HEP) REYNOLDS, EDWARD S. Cardiopulmonary and
renal pathology research center-Chemical basis of ultrastructural
changes in disease (rats).
■17 0013 (HEP) DAMMIN, GUSTAVE J. Cardiopulmonary and renal
pathology research center-Morphologic analysis of vascular prosthesis
(human, dogs).
•17 0014 (HEP) FISHBEIN, MICHAEL C. Cardiopulmonary and renal
pathology research center-Quantitative morphology in cardiac disease
(human, rats, dogs).
17 0015 (HEP) SZABO, SANDOR. Cardiopulmonary and renal
pathology research center-Pathogenesis of chemically induced tissue
injury (rats).
17 0016 (HEP) EHRIE, MICHAEL. Cardiopulmonary and renal
pathoogy research center-Endocarditis with pulmonaiy artery
catheters (dogs).
-17 0017 (HEP) EHRIE, MICHAEL. Cardiopulmonary and renal
pathology research center-Detection of pulmonary lesions-Radiologic
pathologic correlation,
-17 0018 (HEP) PINKUS, GERALDINE. Cardiopulmonary and renal
pathology research center-Cytochemistry and immunology of
lymphoproliferative disorders (human).
-IS (GMA) KAYDEN. HERBERT J, NEW YORK UNIVERSITY 550 FIRST
AVENUE, NEW YORK, N Y. Lipid metabolism (human, rats)
•17 (HEPA) LEAF, ALEXANDER, MASSACHUSEHS GENERAL
HOSPITAL FRUIT STREET, BOSTON, MASS. Cardiopulmonary function in
remediable vascular disease.
17 0010 (HEPA) FREGA, NORBETO. Cardiopulmonary function in
remediable vascular disease-Ischemia and acute renal failure (rats)
17 0034 (HEPA) POWELL, WM JOHN. Cardiopulmonaiy function
in remediable vascular disease-Role of hyperosmolar agents in
ischemic heart disease (dogs).
17 0036 (HEPA) AMES, A DELBERT. Cardiopulmonary function in
remediable vascular disease-In vitro studies on the mechanism of
ischemic damage to cells (rabbits).
17 0037 (HEPA) DIBONA, DONALD R. Cardiopulmonary function
in remediable vascular disease-Salt and water balance of cells and
tissues (rabbits).
POIHL-06314-
POIHl-06314-
P0IHL-063M
P01HL-063I4-
POIHL-06314
P01HL-06314
P01HL-063M
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■ 17 0038 (HIPA) DIBONA, DONALD R. Cafdiopulmonaiy function
in lomednble vascul/ii disease Ihe dynamics ol ADH slimulaled
osmotic water flow
17 0039 (HEPA) DIBONA. DONAIO R. Ciidiopulmonaiy function
in remediable vascular disease Tiansepitlielial active transport and
cell volume legulation (tiogs)
17 0040 (HEPA) CANESSA, MITZY. Cardiopulmonary function in
remediable vascular disease The couplinn of ion transport to metabol
ism (loads)
17 0041 (HEPA) DIBONA, DONALD R. Cardiopulmonary function
in remediable vascular disease-Core facility for quantitative microsco-
py ,
17 0042 (HEPA) LEAF, ALEXANDER. Cardiopulmonary function in
remediable vascular disease Physiologic studies on vein grafts
(dogs)
17 0043 (HEPA) LEAF, ALEXANDER. Cardiopulmonary function in
remediable vascular disease Alveolar hypoxic vasoconstriction Control
and clinical significance (dog. human)
■ 18 (CVB) BAEZ, SILVIO. ALBERT EINSTEIN COLL OF MED. 1300 MOR
RIS PARK AVENUE. BRONX, N Y Biogenic mechanical factors in
microcirculation (rats, gerbils)
.17 (HEP) BUMPUS, F MERLIN. CLEVEUND CLINIC FOUNDATION.
9500 EUCLID AVENUE, CLEVEUNO, OHIO Cardiovascular disease.
■ 17 0014 (HEP) BUTKUS, ANTANAS. Cardiovascular disease-Oiela-
ry induction of severe atherosclerosis and its prevention (dogs).
-17 0015 (HEP) BUTKUS. ANTANAS. Cardiovascular disease-
Plasma cholesterol estenfication m canine atherosclerosis.
-17 0016 (HEP) BUTKUS. ANTANAS. Cardiovascular disease--
Metabolic interactions to polyunsaturated fatty acids in atherogenic
diet (dogs)
-17 0017 (HEP) BUTKUS. ANTANAS. Cardiovascular disease-Stu-
dies on obese hypertensive rats
17 0018 (HEP) BUTKUS. ANTANAS. Cardiovascular disease-Fatty
acid concentration (rats)
17 0019 (HEP) BUTKUS. ANTANAS. Cardiovascular disease -Fatty
acid distribution (rats).
.17 0020 (HEP) BUTKUS. ANTANAS. Cardiovascular disease -Lipid
metabolism (rats).
.17 0021 (HEP) BUTKUS. ANTANAS. Cardiovascular disease--
Animal study in atherosclerosis (dog, guinea pig).
.17 0022 (HEP) BUTKUS, ANTANAS. Cardiovascular disease -Ar-
terial lipogenesis from glucose in the rat.
-17 0024 (HEP) BUTKUS. ANTANAS. Cardiovascular disease -Stu-
dies on the obese spontaneously hypertensive rat.
-17 0026 (HEP) BUTKUS, ANTANAS. Cardiovascular disease--
Lipoproteins (human, guinea pig).
-17 0027 (HEP) SHAINOFF. JOHN R. Cardiovascular disease-Stu-
dies in thrombosis-cross-linking of fibrinogen (human).
-17 0028 (HEP) SHAINOFF. JOHN R. Cardiovascular disease -Stu-
dies in thrombosis-fibrinogen in fibrin transport (human).
-17 0030 (HEP) BUMPUS. F MERLIN. Cardiovascular disease -
Synthesis and pharmacology of angiotensin antagonists (rats, cats).
17 0031 (HEP) BUMPUS. F MERLIN. Cardiovascular disease-
Synthesis of potent antagonist of pressor action of angiotensin II
(animals).
17 0032 (HEP) BUMPUS. F MERLIN. Cardiovascular disease-
Synthesis of angiotensin II as inhibitors for aldosterone.
17 0033 (HEP) BUMPUS, F MERLIN. Cardiovascular disease-Struc-
ture-activity relationship of angiotensin II analogs (rats).
17 0034 (HEP) BUMPUS, F MERLIN. Cardiovascular disease-Stu-
dies of phospholipase A2 in serum (rats. dogs).
.17 0036 (HEP) BUMPUS. F MERLIN. Cardiovascular disease-Purifi-
cation of dog renin.
.17 0037 (HEP) BUMPUS. F MERLIN. Cardiovascular disease -Car-
diac hypertrophy in spontaneously hypertensive rat.
■ 17 0038 (HEP) BUMPUS, F MERLIN. Cardiovascular disease-Effect
of chronic administration of angiotensin antagonist (rats).
-17 0039 (HEP) BUMPUS, F MERLIN. Cardiovascular disease-Rever-
sibility of vascular changes in renal hypertension (rats).
-17 0040 (HEP) FERRARIO, CARLOS M. Cardiovascular disease-
Benign and malignant phase of renal hypertension (dogs).
-17 0041 (HEP) BUMPUS, F MERLIN. Cardiovascular disease-Car-
diac pertormance in rats with renal hypertension.
-17 0042 (HEP) BUMPUS, F MERLIN. Cardiovascular disease-
Myocardial hypertrophy due to renal hypertension (rats).
17 0043 (HEP) BUMPUS, F MERLIN. Cardiovascular disease-Left
atrial receptor activity by the sympathetic nervous system (dogs).
17 0044 (HEP) BUMPUS, F MERLIN. Cardiovascular disease-
Baroreceptors in control of blood pressure during sleep (dogs).
17 0045 (HEP) BRAVO, EMMANUEL L. Cardiovascular disease-
Pressure-volume-renin relationship in human hypertension.
17 0046 (HEP) BRAVO, EMMANUEL L. Cardiovascular disease-
Renin activity during salt depletion in essential hypertension (human).
17 0047 (HEP) BRAVO, EMMANUEL L. Cardiovascular disease--
Spironolactone in primary aldosteroidism (human).
.17 0048 (HEP) BRAVO, EMMANUEL I. Cardiovascular disease-Al-
dosterone producing adenoma prediction of curability (human).
■ 17 0049 (HEP) BRAVO, EMMANUEL L. Cardiovascular disease-
Selective hypoaldosteronism (human).
17 0050 (HEP) BRAVO, EMMANUEL L. Cardiovascular disease-
18-Hydroxylase block in the 17 alpha-hydroxylase deficiency syndrome
(human).
17 0051 (HEP) BRAVO, EMMANUEL L. Cardiovascular disease-
Cardiopulmonary volume in hypertension (human)
17 0052 (HEP) BRAVO, EMMANUEL L. Cardiovascular disease -
Aortic distensibility (human).
17 0053 (HEP) BRAVO, EMMANUEL L. Cardiovascular disease--
Vasodilating drugs (human).
17 0055 (HEP) BRAVO, EMMANUEL I. Cardiovascular disease -
Vascular and adrenocortical response to angiotensin II (dogs)
17 0056 (HEP) BRAVO, EMMANUEL L. Cardiovascular disease -
Angiotensin analogs-Sarcosine on arterial pressure, aldosterone
(dogs).
17 0057 (HEP) BRAVO, EMMANUEL I. Cardiovascular disease-
Studies on cardiac hypertrophy.
P01HL-06S3S
P01HL-0683S
P01HL-06S3S
P01HI-O683S
P01HL-0683S
P01HL-0683S
ROlHl-06924
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R01HL-0697S.
ROIHl-07047
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P01HL-07293
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R01HL-07451
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R01HL-07605
R01HL-07652
R01HL-07723-
PROJECT NUMBER AND INVESTIGATOR ADDRESS
17 00S9 (HEP) BRAVO, IMMANUiL L. CirdlOVltCUlit dlMlM
Melyrapone induced hypertension in dog
17 0060 (HEP) FERRARIO, CARLOS M. Cirdiov»lcul»( ditMM
Ventricular performance experimental modelj of arternl hypertension
(rats, dogs)
17 0061 (HEP) STOWE, N T. Ctrdioviiculat diMite Studiet in
renal physiology (human, rats, dogs)
17 0062 (HEP) EHRHART, I A. Cardiovascufar distau Role of cot
lagen in alhcrosclerosi-, (dogi. pigeons)
17 0063 (HEP) BUTKUS, ANTANAS. Cardiovascular diiease Stu
dies on prostaglandins (human, rabbits)
17 0064 (HEP) NAITO. H K, Cardiovascular disease -Studies in
atherosclerosis (human, animals)
16 (MET) FANBURG. BARRY L, NEW ENGLAND MEO CENTER HOSP.
171 HARRISON AVENUE, BOSTON, MASS Humoral and metabolic
aspects of cardiac function (mammals, non human, human)
17 (HEM) BARTLETT, GRANT R, UB/COMPATATIVE BIOCHEMISTRY.
4620 SANTA FE STREET, SAN DIEGO, CALIF. Red cell metabolism
(human, vertebrates)
18 (CVB) BROW/NIE, ALEXANDER C, S U N Y AT BUFFALO. 180
RACE STREET, BUFFALO, N Y Pathogenesis and prevention of hyper
tension (rats) .
-16 (CVA) TRUEX, RAYMOND C, TEMPLE UNIVERSITY. 3400 NORTH
BROAO STREET, PHILADELPHIA. PA Comparative study of cardiac con.
duction system (human, birds, mammals)
-17 (CVB) LEVINE, HERBERT J, NEW ENGLAND MED CTR HOSP, 171
HARRISON AVENUE, BOSTON, MASS Cardiodynamics and metabolism
of congestive failure (human, dogs)
-17 (HEPA) BAKER, DONAIO W, UNIVERSITY OF WASHINGTON,
CENTER FOR BIOENGINEERING, SEATTLE, WASH Non invasive car
diovascular measurements.
-17 0041 (HEPA) STEW/ART, DOUGLAS K. Noninvasive car-
diovascular measurements-Ventricular volumes and dimensions
(human).
17 0042 (HEPA) BRINKLEY, JAMES. Non-invasive cardiovascular
measurements-Ventricular imaging software (human).
17 0043 (HEPA) BAKER. DONALD W. Noninvasive cardiovascular
mcasurements-ECHO-Doppler instrumentation for cardiac measure-
ments (human).
.17 0044 (HEPA) BAKER. DONALD W. Non-invasive cardiovascular
measurements-Cardiac duplex scanner.
-17 0045 (HEPA) MORITZ. WILLIAM E. Non-invasive cardiovascular
measurements-Cardiac scanner transducer position locating systems
(human).
■ 17 0046 (HEPA) VOSS. DANIEL J. Non-invasive cardiovascular
measurements-Cardiac scanner signal processors.
-17 0047 (HEPA) MORITZ, WILLIAM E. Non-invasive cardiovascular
measurements-Cardiac scanner system software.
-17 0048 (HEPA) BAKER, DONALD W. Non-invasive cardiovascular
measurements-Cardiac scanner recording and display systems com-
ponent.
-17 0049 (HEPA) FORSTER, FRED. Noninvasive cardiovascular mea-
surements-Cardiac scanner engineering evaluation and error analysis.
-17 0050 (HEPA) FORSTER, FRED. Non-invasive cardiovascular mea-
surements-Cardiac dimensions measurements engineering evaluation
and error analysis.
17 0051 (HEPA) JOHNSON, STEVE L. Non-invasive cardiovascular
measurements-Physiologic evaluation of duplex scanner (dogs).
17 0052 (HEPA) JOHNSON, STEVE L. Non-invasive cardiovascular
measurements-Clinical evaluation of the duplex scanner (human).
17 0053 (HEPA) STEWART, DOUGLAS K. Noninvasive car-
diovascular measurements-Clinical evaluation of cardiac dimensions
using the duplex scanner (human).
17 0054 (HEPA) STRANDNESS, D EUGENE. Noninvasive car
diovascular measurements-Detection of arterial occlusive disease
(human).
-17 0055 (HEPA) MORITZ, WILLIAM E. Non-invasive cardiovascular
measurements-Peripheral vascular transducer position locating
system .
-17 0056 (HEPA) MORITZ, WILLIAM E. Non-invasive cardiovascular
measurements-Peripheral vascular system software.
-17 0057 (HEPA) FORSTER, FRED. Non-invasive cardiovascular mea-
surements-Peripheral vascular scanner engineering evaluation and
error analysis (human).
-17 0058 (HEPA) STRANDNESS, D EUGENE. Non-invasive car-
diovascular measurements-Peripheral duplex scanner physiologic
evaluation.
-17 0059 (HEPA) JOHNSON, STEVE L. Non-invasive cardiovascular
measurements-lntracardiac blood flow measurement (human).
13 (HEM) BIOMBACK, BIRGER E, KAROLINSKA INSTITUTET, BLOOD
COAGULATION RES DEPT, S-10401 STOCKHOLM, SWEDEN. Structure
and function of fibrinogen (human).
17 (HEM) BEUTLER, ERNEST, CITY OF HOPE NATL MEDICAL CTR,
1500 EAST DUARTE ROAD, DUARTE, CALIF. Formation and survival of
red blood cells (human).
-16 (BBCB) BRIEHL. ROBIN W, ALBERT EINSTEIN COLLEGE OF MEO,
1300 MORRIS PARK AVENUE, BRONX, N Y. Hemoglobin S gelation and
hemoglobin allostcry (human).
■ 13 (MCHB) BEAl, JACK L, OHIO STATE UNIVERSITY, 500 W 12TH
AVENUE, COLUMBUS, OHIO. Phytochemistry of the genus thalictrum
(dogs, plants).
15 (COM) SCHMITT, OTTO H, UNIVERSITY OF MINNESOTA,
BIOPHYSICS GROUP - 200 TNCE, MINNEAPOLIS, MINN. Analysis of
time-coherent cardiovascular data.
16 (CVA) LEV. MAURICE, HEKTOEN INST FOR MEDICAL RES, 637 S
WOOD STREET, CHICAGO, ILL. Congenital heart disease research pro-
gram (human, dogs).
14 (HEM) JANDL, JAMES H, HARVARD MEDICAL SCHOOL, 25 SHAT-
TUCK STREET, BOSTON, MASS. Destruction of red blood cells in
hemolytic anemias (human, guinea pigs).
15 (PHY) ROTHE, CARL F, INDIANA UNIVERSITY, 1100 WEST
MICHIGAN STREET, INDIANAPOLIS. IND. Reflex control of vascular
capacitance in shock.
PROJECT NUMBER AND INVESTIGATOR ADDRESS
528
R01HL47776-15 (CVA) lOWN, BERNARD, HARVARD SCH OF PUBLIC HLTH 665
HUNTINGTON AVENUE. BOSTON. MASS. Sudden death and cardiac arr-
hythmias (human, dogs. cats).
17 (PTHA) HEPTINSTAU, ROBERT H, JOHNS HOPKINS HOSPITAL
601 NORTH BROADWAY. BALTIMORE, MO. Experimental hypertension
and renal circulation (rats, rabbits).
J6 (MET) EUIOTT, WILLIAM H, ST LOUIS UNIVERSITY, 1402 SOUTH
GRAND BLVD. ST LOUIS. MO. Metabolism of neutral sterols (rats rab-
bits).
»5 (HEP) BENNETT, PETER B, DUKE UNIVERSITY, BOX 3823, DUR-
HAM. N C. Environmental biomedical research program,
IS 0008 (HEP) FARMER, JOSEPH C, JR. Environmental biomedi-
cal research program -Otologic studies under hyperbaric conditions
(human, animals).
IS 0009 (HEP) VANN, R D. Environmental biomedical research pro-
gram-Decompression sickness and computation of safe diving tables
(human, animals).
»5 0014 (HEP) SALZANO, JOHN V. Environmental biomedical
research program-Mechanisms of respiration and circulation (human
dogs).
IS 0019 (HEP) ANDERSON, BANKS, JR. Environmental biomedi-
cal research program-Hyperoxic myopia (human).
IS 0021 (HEP) KYLSTRA, JOHANNES A. Environmental biomedi-
cal research program-Liquid breathing and lung lavage (human).
IS 0029 (HEP) BENNETT, PETER B. Environmental biomedical
research program -Oxygen-helium diving resulting In high pressure
nervous syndrome (human, animals).
IS 0030 (HEP) BENNETT, PETER B. Environmental biomedical
research program-Narcosis caused by inert gases at raised pressures
(human, animals).
■IS 0032 (HEP) HEMPEL, FRANK G. Environmental biomedical
research program-Fluorometry study of brain exposed to hyperbaric ox-
ygen (dogs. cats).
IS 0033 (HEP) SCHMIDT-NIELSEN, KNUT. Environmental
biomedical research program-Breathing mechanism in birds.
IS 0036 (HEP) JOHNSON, CHARLES E. Environmental biomedical
research program -Respiratory heat loss in deep diving (infants
dogs).
IS 0039 (HEP) CRAPO, J D. Environmental biomedical research
program-Development of resistance to lethal effects of oxygen (rats).
IS 0043 (HEP) SPOCK, A. Environmental biomedical research pro-
gram-Effect of hyperbaric oxygen on the lung (human, rabbits).
IS 004S (HEP) MILLER, J N. Environmental biomedical research
program-Extravascular lung water dynamics in pulmonary oxygen tox-
icity (human, baboons).
IS 0046 (HEP) FARMER, JOSEPH C, JR. Environmental biomedi-
cal research program -Treatment of radiation induced tissue injury by
hyperbaric oxygen (human).
IS 0047 (HEP) LYNN, W S. Environmental biomedical research pro-
gram-Pulmonary oxygen toxicity (chickens, rabbits).
15 0048 (HEP) DWYER, H JEFFREY. Environmental biomedical
research program-Respiratory performance in divers at 1400 FSW.
IS 0049 (HEP) SANDERS, A P. Environmental biomedical research
program-Effects of hyperbaric oxygen and pressure on cerebral en-
zymes (rats).
IS 0050 (HEP) VANN, R D. Environmental biomedical research pro-
gram-Fundamental decompression concepts using the rat animal
model.
-IS 00S1 (HEP) HEMPEL, F G. Environmental biomedical research
program -Relationships of retinal circulation to disease (rabbits).
-15 0052 (HEP) DAVIS, JAMES M. Environmental biomedical
research program -Effects of hypoxia on cerebral function.
-IS 0053 (HEP) POTH, P w. Environmental biomedical research pro-
gram-Thermoregulation in asthmatics.
■15 0054 (HEP) HACKEL, DONALD B. Environmental biomedical
research program-Myocardial effects of hemorrhagic shock (dogs).
• 15 0055 (HEP) WANG, H S. Environmental biomedical research
program-Cerebral blood flow by Xenon-133 inhalation (human).
■15 0056 (HEP) KARIS, JOANNES H. Environmental biomedical
research program -Neuromuscular blocking effects of nondepolarizing
muscular relaxants (frogs)
15 0057 (HEP) PHILIP, R B. Environmental biomedical research pro-
gram-Effects of dipyridamole and aspirin on decompression thrombo-
cytopenia (human).
IS 0058 (HEP) BRUMLEY, GEORGE W. Environmental biomedical
research program-Lung synthesis of disaturated phosphatidylcholine
(rats, dogs, bats).
15 0059 (HEP) CHITWOOO, W RANDOLPH. Environmental
biomedical research program-Hyperoxygenation at elevated atmospher-
ic pressure on myocardial blood flow (dogs).
15 0060 (HEP) COSTLOW, JOHN 0. Environmental biomedical
research program-Effect of pressure on development of marine
crustacean larvae.
-IS 0061 (HEP) BELL, D G. Environmental biomedical research pro-
gram-Oxygen cost of breathing during graded exercise (human).
-15 0062 (HEP) ARGELES, H J. Environmental biomedical research
program -Vectorcardiograms during diving (human, dogs).
-IS 0063 (HEP) WOLFE, WALTER G. Environmental biomedical
research program -Oxygen toxicity (baboons).
■15 (HEP) HOLMAN, RALPH T, HORMEL INSTITUTE. 801 16TH AVE
NE. AUSTIN. MINN Chemical and biological properties of lipids.
IS 0005 (HEP) SCHIENK, HERMANN. Chemical and biological
properties of lipids -Metabolism of lipids in animals.
15 0006 (HEP) HOLMAN, RALPH T. Chemical and biological pro-
perties of lipids -Analysis and properties of lipids.
15 0010 (HEP) CHIPAUIT, J R. Chemical and biological properties
of lipids-lnfrarcd spectroscopy of lipids.
IS 0023 (HEP) JENKIN, HOWARD M. Chemical and biological
properties of lipids -Lipids in microorganisms and cell cultures
(hamsters, mosquitoes).
IS 0025 (HEP) SCHMID, HARAlD H o. Chemical and biological
properties of lipidc-Biosynthesis and biological functions of
plasmalogen (cattle).
R0IHI-0783S-
ROIHL-07878
POIHl-07896-
POIHL-07896-
POIHL-07896-
PaiHL-07896-
POIHL-07896
P01HL-07896
POlHL-07896
POIHl-07896-
P01HL-07896
P01HL-07B96
POlHL-07896
POlHL-07896-
POlHl-07896^
POlHL-07896-
P01HL-07896-
POIHL-07896
POlHL-07896
POIHL-07896
POlHl-07896-
POIHL-07896
P01HL-07B96
POIHL-07896
POIHl-07896
POIHL-07896.
P01HL-07896-
POIHL-07896-
P01HL-07896-
POIHL-07896
POIHl-07896'
POIHL-07896-
POIHL-07896-
POlHL-07896-
P01HL-0a2I4
POlHl-08214^
POIHL-08214-
P0IHI-0S2I4-
P0IHL-082I4-
P0IHL-082I4
P01HL.08214-1S 0027 (HEP) BAUMANN, WOLFGANG J. Chemical and biolog-
ical properties of lipids-Biological functions diol lipids (swine rats
plants).
IS 0030 (HEP) SCHMID, HARALD H O. Chemical and biological
properties of lipids-Fatty acid biosynthesis in plant cell cultures and
in plants.
15 0040 (HEP) BAUMANN, WOLFGANG J. Chemical and biolog
ical properties of lipids -Nuclear magnetic resonance studies of lipids.
IS 0041 (HEP) BROCKMAN, HOWARD L. Chemical and biologi-
cal properties of lipids -Physico-chemical regulation of enzymes in
lipid metabolism.
IS 0047 (HEP) PRIVETT, ORVIllE S. Chemical and biological pro-
perties of lipids- High resolution liquid chromatography for the analy-
sis of biological substances.
15 0048 (HEP) SCHLENK, HERMANN. Chemical and biological
properties of lipids -Lipids in microorganisms and plants.
■16 (BIO) KLOTZ, IRVING M, NORTHWESTERN UNIVERSITY 2145
SHERIDAN ROAD. EVANSTON, ILL. Molecular biology of hemeryfhrin and
hemocyanin (invertebrates).
14 (PHRA) HARDMAN, HAROLD F, MEO COLLEGE OF WISCONSIN
561 NORTH 15TH STREET. MILWAUKEE, WIS. Effects of drugs upon
myocardial hypoxia (dogs, turtles).
•14 (PHRA) BEVAN, JOHN A, DEPARTMENT OF PHARMACOLOGY
SCHOOL OF MEDICINE. UCU, LOS ANGELES, CALIF. Morphopharmacolo-
gy of vascular adrenergic transmission (rabbits, rats).
15 (ALY) DES PREZ, ROGER M, VETERANS ADMINISTRATION HOSP
1310 24TH AVENUE. SOUTH. NASHVILLE, TENN. Platelet injury in infec-
tions and allergic diseases (human).
IS (MET) REAVEN, GERALD M, STANFORD UNIVERSITY. SCHOOL OF
MEDICINE, STANFORD. CALIF. Lipemia-carbohydrate and glyceride
metabolism (human, rats).
15 (CVB) HOFFMAN, BRIAN F, COLLEGE OF PHYSICANS & SUR-
GEON. 630 W 168 STREET, NEW YORK. NY. Cardiac conductivity and
automaticity (human, dogs, rabbits).
15 (PHRA) ZIMMERMAN, BEN G, UNIVERSITY OF MINNESOTA 435
DELAWARE STREET, MINNEAPOLIS, MINN. Pharmacologic and reflex In-
fluence on vascular tone (dogs, rabbits).
■15 (MET) DEMPSEY, MARY E, UNIVERSITY OF MINNESOTA. BOX 68
MAYO BUILDING, MINNEAPOLIS, MINN. Enzymic cholesterol synthesis
(human, rats, protozoa, yeast).
■14 (CVA) DOWNING, S EVANS, YALE UNIVERSITY, 333 CEDAR
STREET, NEW HAVEN, CONN. Myocardial performance and metabolism
in the newborn (sheep).
IS (HEP) RANDALL, WALTER C, LOYOU UNIV OF CHICAGO 2160
SOUTH FIRST AVENUE, MAYWOOD, ILL. Regulation of the cardiovascu-
lar system.
IS 0005 (HEP) DOBRIN, PHILIP B. Regulation of the cardiovascu-
lar system-Smooth muscle and mechanical properties of blood ves-
sels (dogs, human).
IS 0006 (HEP) JONES, STEVEN B. Regulation of the cardiovascu-
lar system-Cardiovascular studies of mammalian hibernators
(sciuromorpha).
15 0011 (HEP) BRYNJOLFSSON, GISSUR. Regulation of the car
diovascular system-Histochemistry and ultrastructure of heart inner-
vation (dogs, ground squirrels).
15 0015 (HEP) RANDALL, WALTER C. Regulation of the car-
diovascular system-Projection of autonomic nerves onto the heart
(dog),
IS 0016 (HEP) RANDALL, WAITER C. Regulation of the car
diovascular system -Shifting cardiac pacemakers and AV nodal activa-
tion (dog).
IS 0017 (HEP) RANDALL, WAITER C. Regulation of the car-
diovascular system-Neurally induced cardiac dysrhythmias (dog)
IS 0018 (HEP) RANDALL, WALTER C. Regulation of the car-
diovascular system -Functional implications of cardiac afferent nerves
(dogs).
15 0019 (HEP) FILKINS, JAMES P. Regulation of the cardiovascu-
lar system-Hepatic immunophysiology and host-defense in shock (rat
dog. human).
15 0020 (HEP) FILKINS, JAMES P. Regulation of the cardiovascu-
lar system-Hepatic metabolic basis of shock (rat)
-IS 0021 (HEP) FILKINS, JAMES P. Regulation of the cardiovascu-
lar system-Hypoglycemia in pathogenesis of shock (dog)
-15 0022 (HEP) WURSTER, ROBERT D. Regulation of the car
diovascular system-Blood pressure responses and preganglionic sym-
pathetic outflow (cat).
-IS 0023 (HEP) WURSTER, ROBERT D. Regulation of the car
diovascular system-Cardiovascular control-Effects of spinal pathways
lesions (dog).
•IS 0024 (HEP) WURSTER, ROBERT D. Regulation of the car-
diovascular system-Morphology of the spinal sympathetic system
(cat),
•15 0025 (HEP) WURSTER, ROBERT D. Regulation of the car
diovascular system-Physiology of preganglionic cell bodies (cat)
IS 0026 (HEP) BRAVERMAN, BERTON. Regulation of the car-
diovascular system-Hypertension-High renin vs low renin (dog)
IS 0027 (HEP) BRAVERMAN, BERTON. Regulation of the car-
diovascular system-Cardiac mechanoreceptors-Reflex regulation of
renal function (dogs).
15 0031 (HEP) JACOBS, H KURT. Regulation of the cardiovascular
system-Cardiac electrophysiology in hibernation (ground squirrel mar-
mot),
15 0033 (HEP) GEIS, W PETER. Regulation of the cardiovascular
system-Functional and anatomical relations during cardiac re-innerva-
tion (dog),
15 0036 (HEP) SAYEED, MOHAMMED M. Regulation of the car-
diovascular system -Electrolyte transport in myocardium with hemorr-
hagic shock (rats).
15 0037 (HEP) WEBBER, CHARLES L. Regulation of the car-
diovascular system-Central nervous regulation of cardiopulmonary
mechanisms (cats),
15 0038 (HEP) PACE, JOHN B. Regulation of the cardiovascular
system -Control of pulmonary circulation (dogs).
POIHL-08214
POIHL-08214
POIHL-08214
P0IHL.082I4-
P01HL-08214
ROlHL-08299
R0IHL-083I1
ROlHL-08359-
ROIHL-08399-
R0IHI-08S06
R01HL-08508
R01HL-08S70-
R01HL-08634
ROlHL-08659
POIHL-08682.
POIHL-08682-
POIHL-08682
POIHL-08682
POIHl-08682-
POIHl-08682-
POIHL-08682
POIHL-08682
POlHL-08682-
POIHL-08682
POIHL-08682
POIHL-08682
POIHL-08682.
POIHL-08682^
P0IHL.08682-
POIHl-08682-
POIHl-08682-
POlHL-08682
P01HL-08682-
P01HL-08682
POIHL-08682
POIHL-08682
529
t0IHl-0t696
R01Hl-0t696-
R01HL-08696
R01HI-0S696-
R0IHI-0B696-
ROIHl-08696'
ROIHl-08696
ROIHl-08696
R01HL-08696-
R01HL-08696-
ROIHl-08696'
ROIHl-08789
P01HL-08805
P01HL-0880S
P01HI-0880S-
P0IHL-0B80S-
P01HL-0880S'
P01HL-08805
POIHl-08805
POIHL-08805
POIHl-08805-
P01HL-08805-
PO1HL-0880S'
POIHL-OSeOS
P0IHL-0880S
ROIHl-08888
R01HL-08892
R01HL-08893
P01HL-08899
P01HL-08899-
POIHL-08899-
POIHL-08899-
P01HL-08899
P01HI-08899
P01HL-08899-
P01HL-08899-
POIHl-08899
M (SOYA) SMUMWAV, NORMAN I. SUNFORD UNIVtRSIlY. OfPI
OF CARDIOVASCUUR SURGERY, STANFORD. CALIF Orthotopic ho.rt
tr«nspl»ntation
M 0001 (SOYA) SHUMWAY, NORMAN i. Orthotopic heart
tunsplnntition Itansplantation icnmunolojy Anlithymocyto ilobulln
(cabbils, monkeys)
15 0004 (SOYA) SHUMWAY, NORMAN i. Orthotopic heart
tiansplantalion Iransplantation immunoloiy Avian antibody studies
(chickens. lats. labbits)
IS 0010 (SOYA) SHUMWAY, NORMAN E. Orthotopic heart
liansplantation Transplantation immunology Total lymphoid Iriadia-
tion (dogs, primates)
15 OOn (SOYA) SHUMWAY, NORMAN E. Orthotopic heart
transplantation Transplantation immunology Immunodepressive factor
(human, dogs)
-15 0012 (SOYA) SHUMWAY, NORMAN E. Orthotopic heart
transplantation- Transplantation immunology Modulation ot donor an
tigenicity (dogs)
15 0013 (SOYA) SHUMWAY, NORMAN E. Orthotopic heart
transplantation- Transplantation immunology -Cardiac heterotransplan-
tation (rabtiits. dogs) ,. ^
15 0014 (SOYA) SHUMWAY, NORMAN E. Orthotopic heart
transplantation -Transplantation immunology -Cardiac retcansplanta-
tion (dogs) „^. . I. ,.
15 0018 (SOYA) SHUMWAY, NORMAN E. Orthotopic heart
transplantation -Training in cardiac transplantation.
.15 0019 (SOYA) SHUMWAY, NORMAN E. Orthotopic heart
transplantation -Suppressor cell stimulation (dogs. mice).
-15 0020 (SOYA) SHUMWAY, NORMAN E. Orthotopic heart
transplantation -Complete cardiopulmonary transplantation (dogs).
-1 1 (CVA) SHARP, JOHN T, VETERANS ADMINISTRATION HOSP. POST
OFFICE BOX 7. MINES. ILL Respiratory muscles and ventilatory control
in man (and dogs).
-15 (HEPA) FISHMAN, ALFRED P, HOSP/UNIV OF PENNSYLVANIA.
34TH & SPRUCE STREETS. PHILADELPHIA. PA. Regulation of ventilation
and pulmonary circulation.
15 0006 (HEPA) FISHMAN, AlFREO P. Regulation of ventilation
and pulmonary circulation -Adaptation of lungfish-Estivation.
15 0025 (HEPA) PIETRA, GUISEPPE G. Regulation of ventilation
and pulmonary circulation -Pulmonary edema (rabbits).
■ IS 0039 (HEPA) LAHIRI, S. Regulation of ventilation and pulmonary
circulation-Carotid body (cats).
.15 0042 (HEPA) PIETRA, GUISEPPE G. Regulation of ventilation
and pulmonary circulation-Electron microscope core research laborato-
-15 0043 (HEPA) PIETRA, GUISEPPE G. Regulation of ventilation
and pulmonary circulation-Computer core facility.
-15 0044 (HEPA) FISHMAN, ALFRED P. Regulation of ventilation
and pulmonary circulation-Neurochemical interactions in respiratory
control (human, dogs, goats).
15 0045 (HEPA) PACK, A. Regulation of ventilation and pulmonary
circulation-Integrated description of neurochemical respiratory control
system. , ... .
15 0046 (HEPA) DAVIES, RICHARD O. Regulation of ventilation
and pulmonary circulation-Sites and modes of interaction of
peripheral and central chemoreceptors.
.15 0047 (HEPA) lEVINE, S. Regulation of ventilation and pulmona-
ry circulation-Extracranial metabolic control of ventilation (dogs.
-15 0048 (HEPA) PIETRA, GUISEPPE G. Regulation of ventilation
and pulmonary circulation-Permeability of alveolo-Capillary membrane
in normal pulmonary hypertensive lung.
-15 0049 (HEPA) KNIGHT, DAVID H. Regulation of ventilation and
pulmonaiy circulation-Pulmonary hypertension produced by Dirofilaria
immitis in the dog.
15 0050 (HEPA) WEBER, K T. Regulation of ventilation and pulmo-
nary circulation-Right ventricular mechanics (dogs).
1-12 (SRC) CANNER, PAUL, UNIVERSITY OF MARYUND, 600 WYNO-
HURST AVENUE. BALTIMORE, MO. Cooperative study of drugs and coro-
nary heart disease (men).
-10 (SRC) SERGE, KENNETH B, MAYO FOUNDATION, 200 FIRST ST
SOUTHWEST, ROCHESTER. MINN. Cooperative study of drugs and coro-
nary heart disease. ,, „.„.,.,,-ru
14 (BBCB) GUIDOTTI, GUIDO, HARVARD UNIVERSITY, 16 DIVINITY
AVENUE. CAMBRIDGE, MASS. Structure and function of membrane
proteins (human). „^.,.,.v,.
14 (HEP) LAMBERTSEN, CHRISTIAN J, UNIVERSITY OF PENNSYL
VANIA. 36TH AND HAMILTON WALK, PHILADELPHIA, PA. Tolerance to
respiratory gases in health and disease.
14 0003 (HEP) LAMBERTSEN, CHRISTIAN J. Tolerance to respira
tory gases in health and disease-Inert gas exchange in the eye
(human, dogs).
14 0006 (HEP) LAMBERTSEN, CHRISTIAN J. Tolerance to respira-
tory gases in health and disease-Effects of extreme pressures of inert
gases in macaque monkey.
.14 0007 (HEP) NICHOLS, C J. Tolerance to respiratory gases in
health and disease-Effects of high oxygen pressures on visual func-
tion (human, animals).
-14 0008 (HEP) LAMBERTSEN, CHRISTIAN J. Tolerance to respira-
tory gases in health and disease-Hypoxia in regards to respiratory
and brain circulatory control (goats).
14 0010 (HEP) LAMBERTSEN, CHRISTIAN J. Tolerance to respira
tory gases in health and disease-High oxygen pressure in septic
shock (human).
.14 0012 (HEP) REIVICH, M. Tolerance to respiratory gases in
health and disease-High oxygen for normal brain metabolism and cir-
culation in man.
.14 0013 (HEP) REIVICH, M. Tolerance to respiratory gases in
health and disease-Oxygen and carbon dioxide effects upon human
brain metabolism.
14 0014 (HEP) LAMBERTSEN, CHRISTIAN J. Tolerance to respira
tory gases in health and disease-Cellular and renal responses to
hypercapnia and hypocapnia (dogs).
PROJECT NUMBER AND INVESTIGATOR ADDRESS
P01Hl-0e899-14 0015 (HIP) LAMBIRTSIN, CHRISTIAN J. Tolerance to r..p.r.
lory gasas in health and dmaie Respiratory adaptations to incream
in breathing (human)
P01HL.0e899.14 0017 (HEP) LAMBERTSEN. CHRISTIAN J. Tolerance 10 r.spir.
tory gases in health and disease Pulmonary tolerance (human, dogs)
P01HL.0e899.14 0018 (HEP) LAMBERTSEN, CHRISTIAN J. Tolerance to respire
lory gases in health and disease EllecIs of respiratory gates at n
treme pressures (human)
POIHL-08899. 14 0019 (HEP) LAMBERTSEN, CHRISTIAN J, Tolerance to respira
tory gases in health and disease High oxygen pressure upon carotid
chemoreceotor (cats)
P01HL.08899-14 0020 (HEP) LAMBERTSEN, CHRISTIAN J. Tolerance to .espi.a
tory gases in health and disease Oxygen tolerance (human, rats.
P0IHL.08899.14*00yMHEP) LAMBERTSEN. CHRISTIAN J. Tolerance tO respira
tory gases in health and disease Renal oxygen toxicity (dogs)
POlHL-08899-14 0022 (HEP) LAMBERTSEN, CHRISTIAN D. ^Olera-ice to
respiratory gases in health and disease Effect of inert gas and hydro
static pressures on physiological functions (monkey)
POlHl-08899-14 0023 (HEP) LAHIRI, S. Tolerance to respiratory gases in health
and disease Hypoxia and hyperoxia in respiratory response in regards
to PC02 (human)
POlHl-08899-14 0024 (HEP) GEIFAND, ROBERT. Tolerance to respiratory gases
in health and disease -Effects of oxygen pressures on physiological
control systems (human, dogs).
POlHL-08899-14 0025 (HEP) LAMBERTSEN, CHRISTIAN J. Tolerance to respira
tory gases m health and disease Effects of oxygen on cardiopulmona-
ry gas transport functions (dogs)
POlHL-08899-14 0026 (HEP) LAMBERTSEN. CHRISTIAN J. Tolerance to respira
tory gases in health and disease- Effects of oxygen on central nervous
system functions (rats, rabbits)
POlHL-08899-14 0027 (HEP) LAMBERTSEN, CHRISTIAN J. Tolerance to respira
tory gases in health and disease-Effects of high oxygen pressures on
ethanol metabolism (human).
POlHL-08899-14 0028 (HEP) LAMBERTSEN. CHRISTIAN J. Tolerance to respira
tory gases in health and disease -Inert gas exchange, oxygen in-
fluences-organs and tissues (human, rabbits, dogs).
POlHL-08899-14 0029 (HEP) LAMBERTSEN, CHRISTIAN J. Tolerance to respira
tory gases in health and disease -Isobaric gas counter diHusion
phenomena (human, pigs).
POlHL.08899-14 0030 (HEP) GELFAND, ROBERT. Tolerance to respiratory gases
in health and disease-Dynamic characteristics of respiratory control
components (human, cats).
POIHL.08899.14 0031 (HEP) GELFAND, ROBERT. Tolerance to respiratory gases
in health and disease-Studies in exercise (human, dogs).
POlHL-08899-14 0032 (HEP) GELFAND. ROBERT. Tolerance to respiratory gases
in health and disease-Effects of high oxygen pressures upon respira-
tory control. . ^
POlHL.08899-14 0033 (HEP) GEIFAND, ROBERT. Tolerance to respiratory gases
in health and disease-Acidbase related influences of hypoxia
(human).
P01HL-08899.14 0034 (HEP) GELFAND. ROBERT. Tolerance to respiratory gases
in health and disease-Hyperoxygenation and respiratory response to
acid-base stimuli (human, dog).
POlHL-08899-14 0035 (HEP) CLARK, JAMES M. Tolerance to respiratory gases in
health and disease-Simulation of the increased metabolism of exer-
cise (dogs).
POlHL-08899-14 0036 (HEP) CLARK, JAMES M. Tolerance to respiratory gases in
health and disease-Chemical and neurogenic components of respira-
toiy simulation in exercise (human).
POIHl.08899-14 0038 (HEP) PROCKOP. LEON D. Tolerance to respiratory gases
in health and disease-Brain vessels change in alveolar arterial gas
tensions (human, monkeys).
POlHL-08899-14 0039 (HEP) WOLUWAN. HARRY. Tolerance to respiratory gases
in health and disease-Doseresponse studies of oxygen on C02 reac-
tivity in brain vessels (human).
POlHL-08899-14 0040 (HEP) PUGLIA. CHARLES D. Tolerance to respiratory
gases in health and disease-Metabolic gas influence on brain vascu-
lar tissue (animals).
POlHL-08899-14 0041 (HEP) GELFAND, ROBERT. Tolerance to respiratory gases
in health and disease-Blood gas transport and brain circulatory con-
trol (human).
POlHL-08899-14 0042 (HEP) CLARK, JAMES M. Tolerance to respiratory gases in
health and disease-Definitions and extension of oxygen tolerance in
organ systems (animals).
POlHL-08899-14 0043 (HEP) PROCKOP, LEON D. Tolerance to respiratory gases
in health and disease-Oxygen effects upon CNS and sensory functions
(human).
POlHL-08899-14 0044 (HEP) LAMBERTSON, CHRISTIAN J. Tolerance to
respiratory gases in health and disease-Influence of high oxygen
pressures on cognition and performance.
POlHL-08899-14 0045 (HEP) FLETCHER, DOROTHY. Tolerance to respiratory
gases in health and disease -Studies in normal subjects.
POlHL-08899-14 0046 (HEP) KRON, REUBEN E. Tolerance to respiratory gases
in health and disease-Studies in senile elderly individuals.
POlHL-08899-14 0047 (HEP) LAMBERTSON, CHRISTIAN J. Tolerance to
respiratory gases in health and disease-Oxygen effects on visual
function (human).
POlHL-08899-14 0048 (HEP) NICHOLS, CHARLES W. Tolerance to respiratory
gases in health and disease-Changes in human vision during known
tolerable exposures.
POlHl-08899.14 0049 (HEP) NICHOLS, CHARLES W. Tolerance to respiratory
gases in health and disease-Dose-response measures of severe ox-
ygen toxicity (monkeys).
POlHL-08899-14 0050 (HEP) ROCKEY, JOHN H. Tolerance to respiratory gases
in health and disease-Effects of high oxygen pressures on visual pig-
ment functions (monkeys).
POlHL-08899-14 0051 (HEP) HAUGAARD, NIELS. Tolerance to respiratory gases
in health and disease-Oxygen effects upon isolated retinal metabol-
ism (rabbits, monkeys).
POlHL-08899-14 0052 (HEP) FLETCHER, DOROTHY. Tolerance to respiratory
gases in health and disease-Oxygen effects on auditory and vestibu-
lar function (human, guinea pigs).
PROJECT NUMBER AND INVESTIGATOR ADDRESS
530
P01HL-08899-
POIHL-08899-
P01H1.08899-
P01HL-08899
P01HL-08899-
POIHL-08899
P01HL-08899-
POIHl-08899
POIHL-08899
POIHL-08899'
P01HL-08899-
POIHL-08899-
POIHl-08899-
PO)Hl-08899
POIHl-08899'
POIHL-08899.
POIHL-08899-
P01HL-08899-
P01HL-08899
P01HL-08899-
P01HL-08B99
P01HL-08974
P01HL-08974.
P01HL.08974.
P0)HL-08974-
P01HL-08974
P01HL-08974
ROIHL-08977.
POIHL-0901).
P01HL.090II-
POIHl-09011
P01H 1-090 II
POIHL-0901 1 -
POIHL-0901 1-
P01HL-090I1
POIHl-09011
P0IHl-090n
14 0054 (HEP) LAMBERTSEN, CHRISTIAN J. Tolerance to respira
tory gases in health and disease-Glucose transport across choroid
plexus (dogs).
14 OOSS (HEP) CLARK, JAMES M. Tolerance to respiratory gases in
health and disease-Oxygen effects on organ functions-Extension of
tolerance.
14 00S6 (HEP) CLARK, JAMES M. Tolerance to respiratory gases in
health and disease -Extension of pulmonary oxygen tolerance at in-
creased pressures (animals).
14 0057 (HEP) CLARK, JAMES M. Tolerance to respiratory gases in
health and disease -Studies of intermittent exposure in man
14 0061 (HEP) SOLOWAY, ROGER D. Tolerance to respiratory
gases in health and disease-Hepatic oxygenation and secretory func-
tions (rats, dogs).
14 0062 (HEP) COOPER, DAVID V. Tolerance to respiratory gases
in health and disease-Influence of oxygen at high pressure upon ox-
idation (rats).
14 0064 (HEP) LAMBERTSON, CHRISTIAN J. Tolerance to
respiratory gases in health and disease -Narcotic effects of inert
gases on functional systems (rats).
■14 0065 (HEP) LAMBERTSON, CHRISTIAN J. Tolerance to
respiratory gases in health and disease-Adaptation and effects of
narcotic gases exposure (human).
■14 0066 (HEP) FLETCHER, DOROTHY. Tolerance to respiratory
gases in health and disease-Neurophysiological effects of inert gases
in man.
14 0067 (HEP) NICHOLS, CHARLES W. Tolerance to respiratory
gases in health and disease-Inert gas influences upon visual func-
tion in man.
14 0072 (HEP) QUINN, JOHN A. Tolerance to respiratory gases in
health and disease-Inert gas exchange isobaric gas counterdiffusion
and decompression.
-14 0073 (HEP) QUINN, JOHN A. Tolerance to respiratory gases in
health and disease-Biophysical mechanisms involved in isobaric gas
counterdiffusion syndrome.
-14 0074 (HEP) QUINN, JOHN A. Tolerance to respiratory gases in
health and disease-Biomathematical analysis of isobaric gas
exchange and bubble formation.
■14 0075 (HEP) QUINN, JOHN A. Tolerance to respiratory gases in
health and disease-Gas diffusion rates and bubble formation across
membranes (animals).
•14 0076 (HEP) QUINN, JOHN A. Tolerance to respiratory gases in
health and disease -Bubble formation during gas counterdiffusion
(hamsters).
14 0077 (HEP) QUINN, JOHN A. Tolerance to respiratory gases in
health and disease-lsobaric gas supersaturation patterns
14 0078 (HEP) LAMBERTSON, CHRISTIAN J. Tolerance to
respiratory gases in health and disease-lsobaric gas counterdiffusion-
-Sensoiy, cutaneous and systemic function (animals)
14 0079 (HEP) LAMBERTSON, CHRISTIAN J. Tolerance to
respiratory gases in health and disease-Physiological factors in coun-
terdiffusion bubble formation (human, pigs).
14 0080 (HEP) UMBERTSON, CHRISTIAN J. Tolerance to
respiratory gases in health and disease-Dynamic quantitation of con-
tinuous isobaric gas embolization.
14 0085 (HEP) LAMBERTSEN, CHRISTIAN J. Tolerance to respira-
tory gases in health and disease-Search for gas bubbles in vestibular
fluids (animals).
■14 0089 (HEP) LAMBERTSON, CHRISTIAN J. Tolerance to
respiratory gases in health and disease-Decompression by applica-
tions of optimal control theory.
•14 (HEPS) STRONG, JACK P, LOUISIANA STATE UNIVERSITY 1542
TULANE AVENUE, NEW ORLEANS, LA. Natural and experimental
atherosclerosis.
14 0005 (HEPB) OAIMANN, MARGARET C. Natural and experi-
mental atherosclerosis-Atherosclerosis, coronary heart disease and
sudden death (human).
14 0024 (HEPB) EGGEN, DOUGLAS A. Natural and experimental
atherosclerosis-Atherosclerosis, sterol and lipoprotein metabolism in
nonhuman primates.
■14 0028 (HEPB) TRACY, RICHARD E. Natural and experimental
atherosclerosis-Geographic pathology of atherosclerosis and coronary
heart disease (human).
•14 9001 (HEPB) BHATTACHARYYA, ASHIM K. Natural and ex
perimental atherosclerosis-Core-Lipid chemistry laboratory
•14 9002 (HEPB) TRACY, RICHARD E. Natural and experimental
atherosclerosis-Core-Histology ajid histochemistry laboratory
•14 (PHY) WAYLAND, HAROLD, CALIFORNIA INST OF TECHNOLOGY
1201 EAST CALIFORNIA BLVD. PASADENA, CALIF. Quantitation of flov^
and solute flux in microvessels (cats, rats).
15 (HEPB) KELLNER, AARON, NEW YORK BLOOD CENTER 310 EAST
67TH STREET, NEW YORK, N Y. A research and resource program in
blood.
15 0001 (HEPB) ALLEN, FRED H. A research and resource program
in blood-Genetic markers of human blood and gene mapping
(human).
15 0002 (HEPB) BLOMBACK, G BIRGER. A research and resource
program in blood-Biosynthesis of fibrinogen (dogs).
15 0005 (HEPB) NEURATH, A R. A research and resource program
in blood-Characterization of hepatitis-B antigen and the cause of
serum hepatitis (human).
15 0009 (HEPB) POGO, A OSCAR. A research and resource pro-
gram m blood-Control of RNA synthesis in nucleated cells (yeast
ascites cell).
15 0010 (HEPB) GERMAN, JAMES. A research and resource pro-
gram in blood-Chromosome changes in human genetics
15 0012 (HEPB) FALK, CATHERINE T. A research and resource
program in blood-Theoretical population genetics (human)
15 0013 (HEPB) RUBINSTEIN, PABLO. A research and resource
program in blood -A quantitative study of immunological enhancement
(mice).
15 0015 (HEPB) REDMAN, COLVIN M. A research and resource
program in blood-Regulation of synthesis and transport of diverse
proteins in liver (rats).
POIHL-0901 1 -
POIHL-09011
POIHL-09011
POIHL-0901 1
POIHL-0901 1
POIHL-09011
POIHL-0901 1
ROIHL-09125
ROIHL-09154.
R01HL-09163-
R01HL-09172-
R01HL-09234-
ROIHL-09283
R0IHL-093IS
R01HL-09364-
ROIHl-09474
ROIHl-09476
R01HL-09489
R01HL-09544-
ROIHL-09562-
R01HL-09609-
R0IHL-096IO
R01HL-09622
ROIHL-097n-
ROIHL-09739
R01HL-09744
ROIHL-09831-
ROlHL-09902-
ROIHL-09906-
RC1HL-09906
ROIHL-09906-
ROIHL-09906
ROIHL-09906
R01HL-09906.
ROIHL-09906.
ROIHL-09906-
IS 0017 (HEPB) BRODHEIM, ERIC. A research and resource pro-
gram in blood-Operations research laboratory.
-IS 0018 (HEPB) SZMUNESS, WOLF. A research and resource pro-
gram in blood -Hepatitis B in normal populations -Epidemiology, risk
factors and transmission.
-IS 0019 (HEPB) POGO, A OSCAR. A research and resource pro-
gram in blood-The transport mechanism of mRNA (rat, yeast, ascites
cells).
-15 0020 (HEPB) SZMUNESS, WOLF. A research and resource pro-
gram in blood -Passive immunization in the prevention of transmis-
sion of hepatitis B (human).
-15 0021 (HEPB) WAINFAN, E. A research and resource program in
blood -Regulation of transfer RNA methylating enzymes (rats E coli)
-15 0022 (HEPB) ROWE, A W. A research and resource program in
blood -Cryopreservation of blood components (human).
■15 0023 (HEPB) SZMUNESS. WOLF. A research and resource pro
gram in blood-Evaluation of hepatitis B vaccine in endemic settings
(human).
-14 (MBY) KARNOVSKY, MORRIS J, HARVARD MEDICAL SCHOOL
25 SHAnuCK STREET, BOSTON, MASS. Ultrastructural cytochemistry
(human, chick).
•14 (CVB) HERD. JAMES A. HARVARD MEDICAL SCHOOL, 25 SHAT-
TUCK STREET, BOSTON, MASS. Central control of distribution of organ
blood flow (monkeys).
13 (SSS) SHAPIRO. SANDOR S, JEFFERSON MEDICAL COLLEGE
1015 WALNUT STREET, PHIUDELPHIA, PA. Control mechanisms in
hemostasis (human).
15 (PC) RABINOWITZ, MURRAY, UNIVERSITY OF CHICAGO 950
EAST 59 STREET, CHICAGO. ILL. Protein and RNA synthesis in heart
muscle (rats).
13 (CVB) WELTY, JOSEPH D, JR, UNIVERSITY OF SOUTH DAKOTA
SCHOOL OF MEDICINE. VERMILLION, S OAK. Amino acids of contractile
proteins of failing hearts (dogs, hamsters).
•14 (PHRA) GREENBERG. MICHAEL J. FLORIDA STATE UNIVERSITY
DEPT OF BIOLOGICAL SCIENCES, TALUHASSEE, FLA. Pharmacology of
molluscan hearts (also rabbits).
•15 (SGYB) SABISTON, DAVID C, JR, DUKE UNIVERSITY, DEPT OF
SURGERY, DURHAM, N C. Coronary insufficiency and myocardial
revascularization (human, dogs).
14 (BIO) BRIERLEY. GERALD P. OHIO STATE UNIVERSITY DEPT OF
PHYSIOLOGICAL CHEM, COLUMBUS, OHIO. Ion transport by heart
mitochondria (cattle, rat, rabbit).
11 (TEC) VLAD, PETER, CHILORENS HOSPITAL, 219 BRYANT STREET,
BUFFALO, N Y. Natural history-congenital heart defects-Joint study
(human).
10 (TEC) NADAS. ALEXANDER S. CHILDREN'S HOSP MEDICAL
CENTER, 300 LONGWOOD AVENUE, BOSTON. MASS. Natural history
congenital heart defects -Joint study.
-13 (MET) VAHOUNY, GEORGE V, GEORGE WASHINGTON UNIVERSI-
TY 2300 EYE STREET, N W, WASHINGTON, D C. Myocardial lipid
metabolism and regulation (rats).
-12 (BBCB) HARTSHORNE, DAVID J, CARNEGIE-MELLON UNIVERSI-
TY, 4400 Finn AVENUE, PIHSBURGH, PA. Biochemistry of contractile
proteins (animals).
■'I.^i^^"' SCHREIBER, SIDNEY S, VETERANS ADMINISTRATION
HOSP. 408 FIRST AVENUE, NEW YORK, N Y. Cardiac protein synthesis
overload, alcohol and anoxia (guinea pigs).
•1 1 (SGYB) COLGAN, FRANK J, UNIVERSITY OF ROCHESTER 260
CRITTENDEN BOULEVARD, ROCHESTER, N Y. Lung volume' and
breathing mechanics during anesthesia (human).
14 (GMA) DIETSCHY, JOHN M, UNIVERSITY OF TEXAS 5323
HARRY HINES BOULEVARD, DALLAS, TEX. Control of cholesterol
metabolism-Bile acid transport.
14 (PTHA) STILL, WILLIAM J, VIRGINIA COMMONWEALTH UNIV 1200
EAST BROAD STREET, RICHMOND, VA. Pathogenesis of atherosclerosis
(rats).
13 (CVA) GREENFIELD. JOSEPH C, JR, DUKE UNIVERSITY POST
OFFICE BOX 3246, DURHAM, N C. Instantaneous blood flow in ascend-
ing aorta (human, dogs).
''L*,!fT^.t,' °'**^^^^- J l^WRENCE, 1257 1ST BUILDING, 2200
BONISTEEL BOULEVARD, ANN ARBOR, MICH. Biophysical studies of
proteins (human).
'■'rrirL^'c^'!""^'^*'^' °^^*" ^' ""^'^ON "EG PRIMATE RES
CENTER, 505 N W 185TH AVENUE. BEAVERTON, OREG. Experimental
vascular sclerosis (monkeys, rabbits).
12 (CVB) RUSH, STANLEY. UNIVERSITY OF VERMONT, VOTEY BUILD-
ING, BURLINGTON, VT. Effect of resistivity variations on electrocardio-
gram (human).
13 (HEM) DODDS. W JEAN, NEW YORK STATE DEPT OF HEALTH
EMPIRE STATE PUZA, ALBANY, N Y. Comparative study of coagulation
and vascular disease (animals).
13 (PHY) HOFFMAN, JOSEPH F, YALE UNIVERSITY 333 CEDAR
STREET, NEW HAVEN, CONN. Membrane transport Lsses in re
blood cells.
'l°°,'^!''"o^' '^*''^'^' ■• "■ "«'"'"^"« '^^"^P'rt processes in red
blood cells-Rapid photolytic release of ATP from a protected analog-
Na-K pump of RBC ghosts.
'^ rj,'.""",^' FREEDMAN, J C. Membrane transport processes in
red blood cells-Hemoglobin change and membrane potentials in red
blood cells at varying volumes.
-13 0020 (PHY) FREEDMAN. J C. Membrane transport processes in
red blood cells -Calibration of a fluorescent probe for erythrocytes
-13 0021 (PHY) CALLAHAN, T J. Membrane transport processes in
red blood cells -Membrane potentials in human red blood cells due to
proton gradients.
■13 0022 (PHY) CASTRANOVA, V. Membrane transport processes
in red blood cells-Anion transport in dog and cat red cells
13 0023 (PHY) CASTRANOVA, V. Membrane transport processes
in red blood cells-Cation and anion movements in two sub-groups of
dog erythrocytes.
13 0024 (PHY) RAKITZIS. E T. Membrane transport processes in
red blood cells-Inhibition of sulfate transport in human RBCs by
isothiocyanic acid esters.
531
PROJECT NUMBER AND INVESTIGATOR ADDRESS
ROIHl-09906-13 002S (PHY) OOlDINOfR, J M. Membrant UtlAiol^'>9t^fMi«^
in ted blood cells Mechinism of piopianolol induced Ca dependent K
eltlui tiom human RBCs
R01Hl.099n-l2 (CVR) HAll. CHARIES f, UNIVERSITY OF TEXAS. PHY &
BIOPHYSICS DEPARTMENT, GALVESTON. TEX Hofmonal and dielaiy
modification ol NaCl toxicity (lats) mice)
ROIHl-09913-13 (RAO) HUANO, PENG Y. HI SINAI SCHOOl OF MEDICINE. lOOTH
ST & FIFTH AVENUE. NEW YORK. N Y Cefebral veins Anatomic and
radiologic coiielation (human)
R0IHL-099M-13 (CVB) REGAN, TIMOTHY J, NEW JERSEY OF MEDICAL SCHOOL.
100 BERGEN STREET. NEWARK, N I The myocaidium in diabetes mel-
litus (dogs, monkeys)
R0IHL-0992I-I3 (GMB) MC CAA, ROBERT E. UNIVERSITY OF MISSISSIPPI. 2500
NORTH STATE STREET. lACKSON. MINN Mechanisms related to con
gestive heart failure (dogs, human, rat)
R01Hl-)0009-l3 (CVA) DAWSON, ARTHUR D, SCRIPPS CLINIC & RES FDN.
10666 NORTH TORREY PINES ROAD . LA JOLLA. CALIF Regional lung
function in man
ROIHl-10018-11 (MET) MC CARl, RICHARD I, PENNSYLVANIA STATE UNIVERSITY,
BIOCHEMISTRY & BIOPHYSICS DEPT. UNIVERSITY PARK. PA Effect of
aging on beating heart cells in culture (rats).
ROIHl-10036-13 (HEM) LALEZARI, PARVIZ, MONTEFIORE HOSPITAL & MED CTR.
Ill EAST 21CTH STREET. BRONX. N Y. Biology of red cell antigen-an-
tibody reaction (human)
R01HLO0160-13 (MET) SMITH, lElAND L, UNIVERSITY OF TEXAS. MEDICAL
BRANCH, GALVESTON, TEX Origins of atherosclerosis (human)
R01HL-I0182-13 (PHY) CANNON, PAUl J, COLL OF PHYSICIANS & SURGEONS.
630 WEST 168TH STREET. NEW YORK. N Y Circulatory function and
electrolytic metabolism (dogs, human).
R01HI-I03T6-13 (MET) FISHER, WALDO R, UNIVERSITY OF FLORIDA, BOX J-226,
GAINESVILLE, FLA. Structural studies on low density serum
lipoproteins (human).
R01HL-10330-1) (CVA) NOORDERGRAAF, ABRAHAM, UNIVERSITY OF
PENNSYLVANIA, DEPT OF BIOENGINEERING D2, PHILADELPHIA, PA.
Physiological mechanics of the heart and arteries (dogs, rabbits, hor-
ses).
POIHl-10342-13 (HIBA) PERMUTT, SOLBERT, JOHNS HOPKINS UNIVERSITY. 515
NORTH WOLFE STREET, BALTIMORE. MD. The integrated function of
respiration and circulation.
P0)HL-I0342-13 0006 (HLBA) MITZNER, WAYNE. The integrated function of
respiration and circulation -Lung inflation effects on pulmonary vascu-
lature and interstitial space (dogs).
POIHL-10342-13 0008 (HLBA) PERMUTT, SOLBERT. The integrated function of
respiration and circulation-Respiratory mechanics and the circulation
(human, dogs).
P01HL-10342-T3 0011 (HLBA) FITZGERALD, ROBERT S. The integrated function
of respiration and circulation -Control of respiration 1 -Peripheral
chemoreceptor studies (cats).
POIHL-10342-13 0014 (HLBA) GURTNER, GAIl H. The integrated function of
respiration and circulation -Oxygen and carbon monxide transfer
(human, dogs, sheep).
POIHl-10342-13 0019 (HLBA) TRAYSTMAN, RICHARD J. The integrated tunc
tion of respiration and circulation-Cerebral circulation and metabol-
ism (dogs).
POIHL-10342-13 0023 (HIBA) SYLVESTER, JIMMIE T. The integrated function of
respiration and circulation-Carbon dioxide transport and CSF acid
base balance (hogs. pigs).
POIHL-10342-13 0024 (HLBA) BURNS, BARRY. The integrated function of
respiration and circulation-Cytochrome P450 and physiological
response to hypoxia (rats).
POIHl-10342-13 0025 (HIBA) BURNS, BARRY. The Integra
respiration and circulation -Pulmonary gas exchange and metabolism
(human, dogs, sheep).
POIHL-10342-13 0026 (HIBA) FITZGERALD, ROBERT S. The integrated function
of respiration and circulation-Control of respiration -Characterization
of the aortic body (cats).
POIHL-10342-13 0027 (HLBA) FITZGERALD, ROBERT S. The integrated function
of respiration and circulation-Control of respiration-Cardiovascular
adjustment to hypoxia and carbon monoxide.
POIHL-10342-13 0028 (HLBA) BLEECKER, EUGENE R. The integrated function
of respiration and circulation -Mediator release, hemodynamics and
respiratory function in anaphylaxis (dogs).
POIHL-10342-13 9001 (HLBA) BROMBERGER-BARNEA, BARUCH. The in
tegrated function of respiration and circulation-Technical core.
R01HL-10383-12 (BBCA) HO, CHIEN, UNIVERSITY OF PITTSBURGH, DEPARTMENT
OF LIFE SCIENCES. PIHSBURGH. PA. Physical-chemical studies of
hemoglobins and erythrocyte (human).
R01HL-10384-13 (CVB) BERNE, ROBERT M, UNIVERSITY OF VIRGINIA, DEPT OF
PHYSIOLOGY. CHARLOTTESVILLR. VA. Blood flow and nucleotide
metabolism (animals).
ROIHl-10417-12 (CVB) PLONSEY, ROBERT, CASE WESTERN RESERVE UNIV. 500
WICKENDEN BUILDING. CLEVELAND, OHIO. Multiple systems in elec-
trocardiography (human).
POIHl-10436-13 (HEP) NADAS, ALEXANDER S, CHILDREN'S HOSPITAL. 300
LONGWOOD AVENUE. BOSTON. MASS. A multidisciplinary study of con-
genital heart disease.
POIHL-10436-13 0001 (HEP) NADAS, ALEXANDER S. A multidisciplinary study
of congenital heart disease-Assessment of the outlook for children
with congenital heart disease.
POIHL-10436-13 0002 (HEP) GAMBLE, WALTER J. A multidisciplinary study of
congenital heart disease -Myocardial performance, metabolism and ul-
trastructure (human, cats, rats).
POIHL-10436-13 0005 (HEP) STREIDER, DENISE J. A multidisciplinary study of
congenital heart disease-Pulmonary physiology in congenital heart
disease (human).
POIHL-10436-13 0006 (HEP) LAFARGE, C GRANT. A multidisciplinary study of
congenital heart disease-Ventricular blood pumps and valves (human,
cattle).
POIHL-10436-13 0008 (HEP) ROSENTHAL, AMNON. A multidisciplinary study
of congenital heart disease-Physiologic consequences of chronic
hypoxemia (human).
POIHL-10436-13 0009 (HEP) VANPRAAGH, RICHARD. A multidisciplinary
Study of congenital heart disease -Pathophysiology and morphogenesis
of congenital heart disease (human).
POIHl-10436-13 0014 (HIP) VATNIR, STIPHIN P. A mullldisciplinary itudy of
congenital heart disease Cardiovascular pharmacology (dog)
POIHL-10436-13 OOIS (HEP) VATNIR, STIPHIN P. A multidiiciplinary iludy ol
congenital heart disease Fetal and neonatal cardiovaicular physiology
(sheep)
POIHl-10436-13 0016 (HIP) GERALD, PARK S. A multidisciplinaty study of con
genital heart disease Genetic studies of congenital heart disease
(human)
R01HL-1044S-09 (TEC) FROST, PHILIP H, U S PUBLIC HEALTH SERVICE HOSP,
15TH AVENUE & LAKE STR. SAN FRANCISCO. CA Cooperative study ol
drugs and coronary heart disease (men)
ROIHL-10503-13 (PHY) PAGE, ERNEST, UNIVERSITY OF CHICAGO. 950 EAST 59TH
STREET. CHICAGO. ILL Cardiac ion transport and ultrastructure (rats,
guinea pigs, rabbits)
P01HL-10539-I2 (HEP) ABELMANN, WALTER H, DEPARTMENT OF MEDICINE.
BETH ISRAEL HOSPITAL, BOSTON, MASS Pathophysiology of circula-
tion
P0IHL-10S39-12 0023 (HEP) BENSON, HERBERT. Pathophysiology of circulation
•The relaxation response and therapy of disease stales (human)
POIHl-10539-12 0031 (HEP) BENSON, HERBERT. Pathophysiology of circulation
-Post myocardial infarction care Psychological aspects (human)
P01HL-1 0539-1 2 0064 (HEP) HARTLEY, I HOWARD. Pathophysiology of circula
tion -Exercise physiology and pathophysiology (human)
POIHL-10539-12 0065 (HEP) BENSON, HERBERT. Pathophysiology of circulation
-Physiologic correlates of relaxation (human)
POIHL-10539-12 0066 (HEP) BENSON, HERBERT. Pathophysiology of circulation-
Usefulness of relaxation response in industrial settings
POIHL-10539-12 0067 (HEP) BING, OSCAR H L. Pathophysiology of circulation-
Mechanical, electrophysiological studies -Isolated heart muscle (dog.
rat),
POIHL-10539-12 0068 (HEP) ABELMANN, WALTER H. Pathophysiology of Circu-
lation-Acute and chronic cardiomyopathies (mice. dogs, hamsters,
human).
POIHL-10539-12 0069 (HEP) ABELMANN, WALTER H. Pathophysiology of circu
lation -Ventricular compliance and mechanics in intact ventricles
(human).
POIHL-10539-12 0070 (HEP) RADVANY, PAULO. Pathophysiology of circulation-
Effects of hypertension on myocardial blood flow after coronary occlu-
sion (dogs).
R01HL-1 0567-1 2 (HEM) LANGE, ROBERT 0. UNIVERSITY OF TENNESSEE. 1924
ALCOA HIGHWAY. KNOXVILLE. TENN. Erythropoietin-Immunoassay and
characterization (dogs).
R01HL-1 0582-1 2 (SSS) BRINKHOUS, KENNETH M, UNIVERSITY OF NORTH
CAROLINA. DEPARTMENT OF PATHOLOGY. CHAPEL HILL. N C Thrombo-
sis and hemostasis-Analysis. methods and standards (human, cattle,
venom).
R01HL-1 0608-1 2 (ALY) BUTLER, VINCENT P, JR, COLUMBIA UNIVERSITY. 630 W
168TH STREET. NEW YORK. N Y Digoxin-specific antibodies (human).
R01HL-10612-I3 (CVB) DAVIS, JAMES O, UNIVERSITY OF MISSOURI. PHYSIOLOGY
DEPARTMENT. COLUMBIA, MO. Humoral factors in heart failure and
hypertension.
R01HL-10612-13 0018 (CVB) DAVIS, JAMES O. Humoral factors in heart failure
and hypertension -The pathogenesis of experimental renal hypertension
(dogs, rabbits, rats).
R01HL-10612-13 0019 (CVB) DAVIS, JAMES O. Humoral factors in heart failure
and hypertension-Pathogenesis of hypertension in the spontaneous
hypertensive rat.
R01HL-I0612-13 0020 (CVB) DAVIS, JAMES O. Humoral factors in heart failure
and hyperteiision-The control of renin release in the dog.
R01HL-10612-13 0021 (CVB) DAVIS, JAMES O. Humoral factors in heart failure
and hypertension -The control of aldosterone secretion (dogs).
R01HL-1 0622-1 2 (CVA) SACKNER, MARVIN A, MT SINAI MEDICAL CENTER. 4300
ALTON ROAD, MIAMI BEACH, FLA. Volumes and compliance of pulmo-
nary circulation (human, dogs).
R01HL-I0642-18 (SSS) GLOMSET, JOHN A, UNIVERSITY Of WASHINGTON. DE-
PARTMENT OF BIOCHEMISTRY, SEAHLE, WASH. Plasma cholesterol
metabolism (human, macaca).
R01HL-I0705-09 (TEC) SCHLANT, ROBERT C, EMORY UNIVERSITY. 69 BUTLER
STREET. S E. ATLANTA. GA. Cooperative study of drugs and coronary
heart disease (men).
R01HL-I07I1-12 (TEC) SMITH, WILLIAM M, U S PUBLIC HEALTH SERVICE HOSP.
15TH AVE & LAKE ST, SAN FRANCISCO, CALIF. Cooperative study of
treatment of hypertension (human).
R01HL-10718-10 (TEC) NEIIL, CATHERINE A, JOHNS HOPKINS HOSPITAL. SCHOOL
OF MEDICINE. BALTIMORE. MD. Natural history of congenital heart de-
fects-Joint study (human).
R01HL-10834-09 (HED) CASSIN, SIDNEY, UNIVERSITY OF FLORIDA. DEPARTMENT
OF PHYSIOLOGY. GAINESVILLE. FLA. Fetal and neonatal pulmonary cir-
culation (goats).
R01HL-10880-13 (HEM) DUKES, PETER P, 4650 SUNSET BOULEVARD. LOS AN-
GELES, CALIF. Purification of human erythropoietin for research use.
R01HL-10881-13 (CVB) ZWEIFACH, BENJAMIN W, UNIV OF CALIFORNIA. SAN
DIEGO, AMES-BIOENGINEERING. M-005, LA JOLU, CALIF. Structure and
function of microcirculation (hamsters, rats, cats, dogs).
ROlHL-1 0894-1 2 (GMA) MOSBACH, ERWIN H, PUBLIC HEALTH RES INSTITUTE,
455 FIRST AVENUE, NEW YORK, N Y. Intestinal bacteria and steroid
metabolism (human, guinea pigs, rabbits, rats).
R01HL-1 0897-1 2 (CVA) DE MELLO, WAUMOR C, MEDICAL SCIENCES CAMPUS. G
P 0 BOX 5067. SAN JUAN, P R. Effects of hormones on cardiac elec-
trogenesis (rabbits, guinea pigs, dogs).
R01HL-10914-I0 (GMB) PORUSH, JEROME G, BROOKDALE HOSPITAL MED CTR.
BROOKDALE PLAZA & LINDEN BLVD , BROOKLYN. N Y Renal sodium
transport in experimental aldosteronism (dogs).
R01HL-10933-13 (MET) ZILVERSMIT, DONALD B, CORNELL UNIVERSITY. 202
SAVAGE HALL. ITHACA. N Y. Fat metabolism and atherosclerosis
(rabbits, cattle, human, rats).
ROIHL-10940-13 (MET) ZILVERSMIT, DONALD B, CORNELL UNIVERSITY. 202
SAVAGE HALL. ITHACA. N Y. Lipid transport (rabbits, cattle, chickens).
R01HL-1 0942-09 (CVA) SIMPSON, FREDERIC O, WELLCOME MED RES INST. POST
OFFICE BOX 913. DUNEDIN. NEW ZEALAND. Study of genetic hyperten-
sion in rats.
R01HL-10951-11 (CVA) LEVY, MATTHEW N, MT SINAI HOSPITAL. 1800 E 105
STREET, CLEVELAND, OHIO. Neural control of the heart (dogs. rats).
PROJECT NUMBER AND INVESTIGATOR ADDRESS
ROIHL-10980-n (PTHA) SPARGO, BENJAMIN H, UNIVERSITY OF CHICAGO 950
EAST 59TH STREET, CHICAGO. ILL. Ultrastructural renal pathology
(human, rats).
R01HL-1 1046-12 (CVB) SCHAMBELAN, MORRIS, SAN FRANCISCO GENERAL
HOSPITAL. 1001 POTRERO AVENUE. SAN FRANCISCO. CALIF. Renin, an-
giotensin, steroids, ions and blood pressure (human, sheep, rabbits).
R01HL-1in9-17 (BIO) MARGOUASH. EMANUEL, NORTHWESTERN UNIVERSITY
BIOCHEM & MOLECULAR BIO DEPT. EVANSTON. ILL. Amino acid
analyzer for biochemical research.
R01HI-11IS2-12 (CVB) SOBIN, SIDNEY S, 1200 NORTH STATE STREET. BOX
1800. LOS ANGELES, CALIF. Vascular physiology (human, cats, dogs)
ROIHL-1 1 153-12 (PHY) FRASHER, WALLACE G, JR, UNIV OF SOUTHERN
CALIFORNIA, 1200 NORTH STATE ST, BOX 1800 , LOS ANGELES, CALIF.
Quantitation of flow and solute flux in microvcssels (cats, rats)
ROIHl-1 1154-12 (HEM) GREENWAIT, TIBOR J, AMERICAN NATIONAL RED
CROSS. 1730 E STREET. N W, WASHINGTON, D C. Blood group an-
tigens and antibodies (human).
ROIHl-l 1172-12 (HEM) KLINE, DANIEL L, UNIVERSITY OF CINCINNATI. EOEN AND
BETHESDA AVENUES. CINCINNATI. OHIO. Physiology and biochemistry
of fibrinolytic enzymes (human, animals).
ROIHL-1 1289-12 (CVA) SHARMA, M G, PENNSYLVANIA STATE UNIVERSITY 224A
HAMMOND BUILDING. UNIVERSITY PARK. PA. Analysis of stress in pul-
satile dynamics.
P01HL-1 1307-12 (HEPA) SPACH, MADISON S. DUKE MEDICAL CENTER. BOX
3090, DURHAM. N C. Biophysical studies in pediatric cardiology
P01HL-1 1307-12 0002 (HEPA) SPACH, MADISON S. Biophysical studies in
pediatric cardiology-Cardiac extracellular electrophysiology (human,
dog. chimpanzee).
POIHl-1 1307-12 0003 (HEPA) JOHNSON, E A. Biophysical studies in pediatric
cardiology-Cellular biophysics (animals).
POIHl-1 1307-12 9001 (HEPA) GALLIE, THOMAS M. Biophysical studies in
pediatric cardiology -Core support-computer science.
P01HL.n307-12 9002 (HEPA) PILKINGTON, THEO C. Biophysical studies in
pediatric cardiology-Biomedical engineering.
POIHl-l 1310-12 (HEPA) JAMES, THOMAS N, UNIVERSITY OF ALABAMA, UNIVER-
SITY STATION. BIRMINGHAM, ALA. Mechanisms of cardiovascular dis-
ease.
POIHL-1 1310-12 0053 (HEPA) KOUCHOUKOS, NICHOLAS T. Mechanisms of
cardiovascular disease -Ventricular pressure-volume after cardipulmo-
nary bypass (dogs).
POlHL-1 1310-12 0054 (HEPA) BLACKSTONE, EUGENE H. Mechanisms of car
diovascular disease -Mathematical model of ventricular pressure-
volume (human, dogs).
POlHL-1 1310-12 0055 (HEPA) KOUCHOUKOS, NICHOLAS T. Mechanisms of
cardiovascular disease -Ventricular pressure-volume after intracardiac
surgery (human).
POIHL-1 1310-12 0056 (HEPA) KIRKLIN, JOHN W. Mechanisms of cardiovascu
lar disease-Cardiac output response to blood pressure reduction in in-
fants (human).
POIHL-1 1310-12 0057 (HEPA) KOUCHOUKOS, NICHOLAS T. Mechanisms of
cardiovascular disease -Blood pressure reduction after heart surgery in
adults (human).
POIHL-1 1310-12 0058 (HEPA) SHEPPARD, LOUIS C. Mechanisms of car
diovascular disease-Dynamic response to vasodilating agents
postoperatively (human).
POlHL-1 1310-12 0059 (HEPA) KIRKLIN, JOHN W. Mechanisms of cardiovascu-
lar discase-Contractility-Acute response to diogoxin after heart sur-
gery (children).
POIHl-l 1310-12 0060 (HEPA) BLACKSTONE, EUGENE H. Mechanisms of car
diovascular disease-Effect of left atrium on the circulation -Simula-
tion.
POlHL-l 1310-12 0061 (HEPA) BLACKSTONE, EUGENE H. Mechanisms of car
diovascular disease-Computer simulation of transposition of great ar-
teries in infants.
POIHl-1 1310-12 0062 (HEPA) DIGERNESS, STANLEY B. Mechanisms of car-
diovascular disease-Myocardial depressant factor in postoperative
cardiac dysfunction (human, dogs).
POIHl-1 1310-12 0063 (HEPA) ARCHIE, JOSEPH P. Mechanisms of cardiovascu-
lar disease-Myocardial function, metabolism and cellular integrity
after heart surgery (dogs).
POIHL-1 1310-12 0064 (HEPA) KOUCHOUKOS, NICHOLAS T. Mechanisms of
cardiovascular disease-Extracardiac anatomical correction of trans-
position of great arteries (puppies).
POlHL-1 1310-12 0065 (HEPA) SHEPPARD, LOUIS C. Mechanisms of car-
diovascular disease-Algorithms for arterial pressure by automatic
vasoactive agents control (human).
POIHl-1 1310-12 0066 (HEPA) SHEPPARD, LOUIS C. Mechanisms of car
diovascular disease-Measurement of cardiac output by thermodilutlon
(children).
POIHL-1 1310-12 0067 (HEPA) KIRKLIN, JOHN W. Mechanisms of cardiovascu
lar disease-Cardiac performance with measured hemodynamic varia-
bles (human).
POIHl-l 1310-12 0068 (HEPA) BLACKSTONE, EUGENE H. Mechanisms of car
diovascular disease -Pharmacological intervention and myocarcial ox-
ygen consuption (human, dogs).
POlHL-l 1310-12 0069 (HEPA) BLACKSTONE, EUGENE H. Mechanisms of car
diovascular disease-Factors affecting mortality and morbidity after
heart surgery (human).
POIHL-1 1310-12 0070 (HEPA) KIRKLIN, JOHN W. Mechanisms of cardiovascu
lar disease -Factors affecting long-term mortality and morbidity after
heart surgery (human).
P01HL-11310-12 0071 (HEPA) WALDO, ALBERT I. Mechanisms of cardiovascu-
lar disease -Electrophysiological studies of atrial flutter (human)
POIHl-l 1310-12 0072 (HEPA) WALDO, ALBERT I. Mechanisms of cardiovascu
lar disease-Electrophysiological studies of atrial tachycardia with
block (human).
POIHL-1 1310-12 0073 (HEPA) WALDO, ALBERT I. Mechanisms of cardiovascu
lar disease -Electrophysiological study of atrial fibrillation (human)
POlHl-l 1310-12 0074 (HEPA) WAIDO, ALBERT I. Mechanisms of cardiovascu
lar disease-Electrophysiological studies of paraxysmal atrial tachycar
dia (human).
POIHL-1 1310-12 0075 (HEPA) WALDO, ALBERT L. Mechanisms of cardiovascu
lar disease-Bipolar atrial electrograms from Bachmann's bundle
(dogs).
532
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POIHL-1 1310-
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12 0076 (HEPA) WALDO, ALBERT I. Mechanisms of cardiovascu
lar disease -Tratment of depressed cardiac output following heart sur-
gery (children, puppies).
12 0077 (HEPA) MACLEAN, WILLIAM A H. Mechanisms of car
diovascular disease -Abnormalities of rhythm and conduction following
heart surgery (human).
12 0078 (HEPA) WALDO, ALBERT L. Mechanisms of cardiovascu-
lar disease-Ventricular arrhythmias in acute myocardial infarction
(dogs).
12 0079 (HEPA) URTHALER, FERDINAND. Mechanisms of car
diovascular disease-Electrophysiological studies of complete heart
block (human).
12 0080 (HEPA) RACKLEY, CHARLES E. Mechanisms of car
diovascular disease-Metabolism of the hypertrophied myocardium
(human).
-12 0081 (HEPA) HOOD, WILLIAM P. Mechanisms of cardiovascu-
lar disease -Analysis of regional left ventricular function (human).
-12 0082 (HEPA) COGHAN, H CECIL. Mechanisms of cardiovascu
lar disease-Myocardial function in adult congenital heart disease
(human).
■ 12 0083 (HEPA) BAXLEY, WILLIAM A. Mechanisms of car
diovascular disease-Ventricular volume and hemodynamics in adult
congenital heart disease.
•12 0084 (HEPA) BAXLEY, WILLIAM A. Mechanisms of car
diovascular disease-Evaluation of cardiac function in chronic renal
failure (human).
■12 0085 (HEPA) HEFNER, LLOYD L. Mechanisms of cardiovascular
disease-Mechanics of isolated cardiac muscle (animals).
12 0086 (HEPA) HEFNER, LLOYD L. Mechanisms of cardiovascular
disease-Mechanics of the intact left ventricle (dogs).
12 0087 (HEPA) JAMES, THOMAS N. Mechanisms of cardiovascu-
lar disease-Electrophysiology and electropharmacology of the heart
(dogs).
12 0089 (HEPA) JAMES, THOMAS N. Mechanisms of cardiovascu-
lar disease-Structure and function in myocardial contraction (dogs).
-12 0090 (HEPA) JAMES, THOMAS N. Mechanisms of cardiovascu
lar discase-Clinicopathological cardiovascular correlation (human,
animals).
-12 0091 (HEPA) EDDIEMAN, E E. Mechanisms of cardiovascular
disease-Noninvasive techniques in cardiovascular diagnosis (human).
-12 0092 (HEPA) SHEFFIELD, THOMAS L. Mechanisms of car-
diovascular disease-Exercise electrophysiology (human).
-12 0093 (HEPA) HOLT, JOHN H. Mechanisms of cardiovascular
disease-Multiple dipole electrocardiogram project (human, dogs).
■12 0094 (HEPA) KUP, WILLIAM. Mechanisms of cardiovascular dis-
ease-Physics of pulsatile fluid flow (dogs)
•12 0095 (HEPA) CONRAD, MARCEL E. Mechanisms of car-
diovascular disease-Blood and transfusion disorders (human, rats,
monkeys).
12 0096 (HEPA) STROUD, ROBERT M. Mechanisms of car-
diovascular disease-Complement chemistry and biology (human, rab-
bits).
12 0097 (HEPA) ACTON, RONALD T. Mechanisms of cardiovascu-
lar disease-Structural-functional relationships of neuronal differential
alloantigens (mice).
12 0098 (HEPA) BENNETT, CLAUDE. Mechanisms of cardiovascu-
lar disease-Protein chemistry of thy-1 and related synaptosomal
proteins (mice).
12 0099 (HEPA) NIEOERMIER, WILLIAM. Mechanisms of car
diovascular disease -Carbohydrate chemistry of thy-1 and related
synaptosomal proteins.
12 0100 (HEPA) BISHOP, DAVID H I. Mechanisms of cardiovascu-
lar disease-Structure and replication of arenavirus and Bunyam-
weraviruses.
i-12 0101 (HEPA) URRY, DAN W. Mechanisms of cardiovascular
disease-Molecular pathogenesis of vascular disease.
12 0102 (HEPA) BRADLEY, RONALD J. Mechanisms of car-
diovascular disease -Cardiac membrane and ion mobility (dogs).
12 0103 (HEPA) RODEN, LENNART. Mechanisms of cardiovascu-
lar disease-Heparin-Metabolism and function.
1-12 0104 (HEPA) BAKER, JOHN. Mechanisms of cardiovascular dis-
ease-Structure of connective tissue proteoglycans (rabbits)
12 0105 (HEPA) SCHUTZBACH, JOHN. Mechanisms of car-
diovascular disease-Biosynthesis of mammalian glycoproteins
(rabbits).
12 0106 (HEPA) MILLER, EDWARD. Mechanisms of cardiovascular
disease-Biochemical characterization of the collagens in vascular tis-
sue (caftc).
1-12 9001 (HEPA) JAMES, THOMAS N. Mechanisms of cardiovascu
lar disease-Core support-hospital beds.
12 9002 (HEPA) JAMES, THOMAS N. Mechanisms of cardiovascu-
lar disease-Core support-centralized electronic laboratory
1-12 9003 (HEPA) MACY, JOSIAH, JR. Mechanisms of cardiovascu-
lar disease-Core support-biophysical sciences.
■12 9004 (HEPA) MACY, JOSIAH, JR. Mechanisms of cardiovascu-
lar disease-Core support-computer facilities.
•12 (HEPA) BRADY, ALLAN J, UNIVERSITY OF CALIFORNIA DEPART-
MENT OF PHYSIOLOGY, LOS ANGELES, CALIF. Cellular and molecular
mechanisms of myocardial function.
12 0001 (HEPA) LANGER, GLENN A. Cellular and molecular
mechanisms of myocardial function-Ionic control of myocardial con-
tractility (animals).
12 0002 (HEPA) LANGER, GLENN A. Cellular and molecular
mechanisms of myocardial function-Effects of hypoxia and ischemia
on ionic exchange (rats, rabbits).
12 0003 (HEPA) BRADY, ALLAN J. Cellular and molecular
mechanisms of myocardial function -Mechanical and electrical proper-
ties of cardiac muscle (rabbits).
-12 0004 (HEPA) MOMMAERTS, WILFRIED F H M. Cellular and
molecular mechanisms of myocardial function-Molecular mechanisms
of contractile function and differentiation (animals).
-12 0005 (HEPA) BRADY, ALLAN J. Cellular and molecular
mechanisms of myocardial function-Electrophysiology of cardiac
muscle (rats).
S33
PROJECT NUMBER AND INVESTIGATOR ADDRESS
POIHl-1 1351-12 0006 (HEPA) HOMSHIR, lARL. Cellular and moleculai
mtchanisms ol myocaidial tunclion Molecular physiology and enei
letics ot muscle (t(0|s)
POIHl-nssi-IS 0009 (HEPA) lANOER, OlENN A. Cellular and molecular
mechanisms ol myocaidial function Myocardial membrane surlace
coat (rats, rabbits)
P0lHL-n3Sl-l3 0010 (HEPA) lANGER, OlENN A. Cellular and molecular
mechanisms ol myocardial function Basic ionic eichange studies
(rats)
P0)HI-113S1-I2 0011 (HEPA) LANOER, OlENN A. Cellular and molecular
mechanisms at myocardial lunction-Comparalive contractile tissue
studies (animals)
POIHL-1 1351-12 0013 (HEPA) SANBORN, WARREN O. Cellular and molecular
mechanisms of myocardial function Ion exchange in the perfused Sep
tum high resolution technique (rabbits, rats)
POIHl-1 1351-13 0015 (HEPA) SHINE, KENNETH I. Cellular and molecular
mechanisms of myocardial function- Effects of hypoxia and ischemia
on ion exchange and heart function (rabbits)
P01HL-n3S1-12 0018 (HEPA) TORMEY, JOHN MCD. Cellular and molecular
mechanisms of myocardial function Quantitative localization of elec-
trolytes in cardiac tissue
P01HL-1 1351-12 0019 (HEPA) BRADY, ALLAN J. Cellular and molecular
mechanisms of myocardial function -Mechano-chemical kinetics of
small perturbations
POIHl-1 1351-12 0020 (HEPA) HEATH, MILAN J. Cellular and molecular
mechanisms of myocardial function- Electrophysiology of cultured
heart cells
POIHL-1 1351-12 0021 (HEPA) HOMSHER, EARL E. Cellular and molecular
mechanisms of myocardial function -Muscle energetics (frogs)
POIHL-1 1351-12 0022 (HEPA) KEAN, CHARLES J C. Cellular and molecular
mechanisms of myocardial function -Energetic sequelae of shortening -
Myothermal and biochemical (frogs)
P01HL-11351-12 0023 (HEPA) KEAN, CHARLES J C. Cellular and molecular
mechanisms of myocardial function -Energetics of mammalian muscle
(rats).
POIHl-l 1351-12 0024 (HEPA) HOMSHER, EARL E. Cellular and molecular
mechanisms of myocardial function-Steady state and transient
kinetics of frog myosin, S-1. and ATPase.
R01HL-1 1372-08 (TEC) LAUBACH, CHARLES A, JR, GEISINGER MEDICAL
CENTER. INST OF MED EOUC & RESEARCH. DANVILLE, PA. Cooperative
study of drugs and coronary heart disease (men).
POIHL-1 1414-11 (HLBB) SALZMAN, EDWIN W, BETH ISRAEL HOSPITAL, 330
BROOKLINE AVENUE, BOSTON, MASS. Thrombosis and atherosclerosis
program.
POIHL-1 1414-11 0004 (HLBB) SALZMAN, EDWIN W. Thrombosis and atheros-
clerosis program-Platelet function and nonthrombogenic surfaces
(human)
POIHL-1 1414-11 0014 (HLBB) SPARK, RICHARD F. Thrombosis and atherosclero-
sis program-Role of adrenal in human essential hypertension.
POIHL-1 1414-11 0024 (HLBB) PAULIN, SVEN. Thrombosis and atherosclerosis
program-Radiographic demonstration of small coronary arteries
(human, dogs).
POIHL-1 1414-11 0027 (HLBB) SIMON, MORRIS. Thrombosis and atherosclerosis
program-Thermal memory wire filter to prevent pulmonary embolism
(human, dogs).
POIHL-1 1414-11 0028 (HLBB) LANDSBERG, LEWIS. Thrombosis and atheros-
clerosis program-Catecholamine metabolism in the lung (rat).
POIHL-1 1414-11 0033 (HLBB) FRIEDMAN, PAUL A. Thrombosis and atheros-
clerosis program-Human coumarin-induced prothrombin.
POIHL-1 1414-11 0034 (HLBB) MCMAHON, THOMAS A. Thrombosis and
atherosclerosis program-Servo simulation-Experimental myocardial in-
farction (dogs).
POIHl-1 1414-11 0035 (HLBB) FRIEDMAN, PAUL A. Thrombosis and atheros-
clerosis program-Mechanism of action of vitamin K (rats).
POIHL-1 1414-11 0036 (HLBB) FREIMAN, DAVID G. Thrombosis and atheros-
clerosis program-Electron microscopy core facility.
POIHL-1 1414-11 0037 (HLBB) STEMERMAN, MICHAEL B. Thrombosis and
atherosclerosis program-Vascular intimal injury and healing (rabbits,
rats).
ROlHl-l 1418-09 (MCHB) AllCOCK, HARRY R, PENNSYLVANIA STATE UNIVERSI-
TY, 152 DAVEY BUILDING, UNIVERSITY PARK, PA. Poly-
diaminophosphazenes
ROIHl-1 151 1-10 (BMT) USTOWSKY, IRVING, ALBERT EINSTEIN COLLEGE OF
MED, 1300 MORRIS PARK AVENUE, BRONX, N Y. Structure of ferritin
and its role in iron metabolism (horse, rats, human).
ROIHL.11551-11 (PC) FLORINI, JAMES R, SYRACUSE UNIVERSITY, 209 LYMAN
HALL, SYRACUSE, N Y. RNA and protein synthesis in repair of heart
injury (mice, rats).
ROIHL-1 1614-1 1 (NTN) O'DELl, BOYD L, UNIVERSITY OF MISSOURI, 322 CHEMIS-
TRY BLDG, COLUMBIA, MO. Trace elements in nutrition (chickens, rats,
human).
POIHl-1 1678-11 (HEPA) GUYTON, ARTHUR C, UNIVERSITY OF MISSISSIPPI,
2500 NORTH STATE STREET, JACKSON, MISS. Cardiovascular dynamics
and their control.
POIHL-1 1678-11 0001 (HEPA) MANNING, R DAVIS, JR. Cardiovascular
dynamics and their control-Body fluid volumes in the genesis of
hypertension (rats, dogs).
POlHl-1 1678-11 0009 (HEPA) MILHORN, HOWARD T. Cardiovascular dynam
ics and their control-Control of respiration (cat, human).
POIHL-1 1678-11 0017 (HEPA) GUYTON, ARTHUR C. Cardiovascular dynamics
and their control-Overall control of circulation-Mathematical analyses.
POIHL-1 1678-11 0020 (HEPA) PARKER, JAMES C. Cardiovascular dynamics and
their control-Circulatory and pulmonary fluid dynamics during pulmo-
nary edema.
POIHL-1 1678-11 0027 (HEPA) COWLEY, ALLEN W, JR. Cardiovascular dynam
ics and their control -Vasopressin and thirst in control of body fluid
volumes and osmolality (dogs).
POIHl-11678-11 0031 (HEPA) NORMAN, ROGER A, JR. Cardiovascular
dynamics and their control-Hypertension caused by stimulation of
renal sympathetic nerves (dogs).
POIHL-11678-11 0034 (HEPA) DECLUE, JAMES W. Cardiovascular dynamics
and their control -Renal function curves in intact dogs.
POIHL-11678-11 0035 (HEPA) BRACE, ROBERT A. Cardiovascular dynamics and
their control-Lymph flow rate and protein concentration (dogs).
P0IHl-n67S-ll 0036 (HiPA) TAYLOR, AUBRiV i. Cirdiovatcular dynamics
and then control Pulmonary capillary dynamics and edema Idogt)
POIHL-11678-11 0039 (HEPA) TAYLOR, AUBREY i. Cardiovascular dynamic*
and their control Capillary and intcrslitial fluid dynamics ol the in
lestine (cats)
POIHL-1 1678-1 1 0040 (HEPA) YOUNO, DAVID B. Cardiovascular dynamics and
their control Control ol plasma potassium concentration (dogs)
POIHL-11678-11 0043 (HEPA) CROWELL, JACK W. Cardiovascular dynamics
and their control Basic mechanisms of circulatory shock (dog)
POlHl-1 1678-11 0046 (HEPA) MCCAA, ROBERT E. Cardiovascular dynamici
and their control Regulatio,. of aldosterone secretion and related fac
tors (dogs)
POIHl-1 1678-11 0047 (HEPA) MCCAA, ROBERT E. Cardiovascular dynamics
and their control Unidentified pituitary factor in regulation of al-
dosterone secretion (rats)
POIHl-l 1678-1 1 0051 (HEPA) JACKSON, THOMAS E. Cardiovascular dynamics
and their control Transient glomerular filtration dynamics (dogs)
POIHL-11678-11 0057 (HEPA) BENGIS, ROY G. Cardiovascular dynamics and
their control Return of urine to circulation using cysticocaval shunt
(dogs)
POIHL-11678-11 0058 (HEPA) COLEMAN, THOMAS O. Cardiovascular dynam
ics and their control- Overall control ol the circulation-Computer anal-
ysis
POIHL-11678-11 0059 (HEPA) MANNING, R DAVIS, JR. Cardiovascular
dynamics and their control- Basic hemodynamics (dogs, rats)
POIHL-11678-11 0060 (HEPA) NORMAN, ROGER A, JR. Cardiovascular
dynamics and their control- Salt and water balance in one kidney
Goldblatt hypertension (rat)
POIHL-11678-11 0063 (HEPA) HALL, JOHN E. Cardiovascular dynamics and
their control Renin-angiotensin system -Control of renal hemodynam
ics, electrolyte excretion.
POIHL-11678-11 0064 (HEPA) HALL, JOHN E. Cardiovascular dynamics and
their control -Renal medulla-Control of renal hemodynamics, elec-
trolyte excretion (dogs)
POIHL-11678-11 0065 (HEPA) YOUNG, DAVID B. Cardiovascular dynamics and
their control-Body fluid volumes in the genesis of hypertension
(dogs).
POIHL-11678-11 0066 (HEPA) lOHMEIER, THOMAS E. Cardiovascular dynam-
ics and their control -Closed loop analysis of the aldosterone control
system (dogs).
POIHL-11678-11 0067 (HEPA) LOHMEIER, THOMAS E. Cardiovascular dynam-
ics and their control -Angiotension II, sodium excretion and renal
hemodynamics (dogs).
POIHL-11678-11 0068 (HEPA) COLEMAN, THOMAS G. Cardiovascular dynam-
ics and their control-Basic hemodynamics (rats, dogs).
POIHL-11678-11 0069 (HEPA) COWLEY, ALLEN W, JR. Cardiovascular dynam-
ics and their control-Nervous control of the cirulation (dogs).
POIHL-11678-11 0070 (HEPA) BRACE, ROBERT A. Cardiovascular dynamics and
their control-Interaction of the four Starling forces (dogs).
POIHL-11678-11 9001 (HEPA) COLEMAN, THOMAS G. Cardiovascular dynam-
ics and their control -Core-Computer services.
POIHL-11678-11 9002 (HEPA) COWLEY, ALLEN W, JR. Cardiovascular dynam-
ics and their control -Core-Radioimmunoassay and chemical laborato-
ry.
POIHL-11678-11 9003 (HEPA) GUYTON, ARTHUR C. Cardiovascular dynamics
and their control-Core-lnstrumentation and machine shop.
ROIHL-1 1686-09 (HEM) TAKEDA, YASUHIKO, UNIVERSITY OF COLORADO, 4200
EAST NINTH AVENUE. DENVER. COLO. Dynamics of thrombus formation
and dissolution (human, chickens).
ROIHL-1 1717-09 (CVA) YOUNG, DONALD F, IOWA STATE UNIVERSITY. 207
LABORATORY OF MECHANICS, AMES, IOWA. Effect of stenotic obstruc-
tions on flow in arteries (dogs).
ROIHL-1 1775-11 (HEM) HARKER, LAURENCE A, HARBORVIEW MEDICAL CENTER,
325 9TH AVENUE, SEATTLE, WASH. Platelet mechanisms in disease
(human, primates).
ROlHL-1 1802-10 (SGYA) HYMAN, ALBERT L, TULANE MEDICAL SCHOOL, 1430 TU-
LANE AVENUE, NEW ORLEANS. LA. Cardiovascular surgical research
(dogs, sheep, swine, cats, monkeys).
ROIHL-1 1822-10 (BBCB) HASCHEMEYER, RUDY H, CORNELL UNIVERSITY, 1300
YORK AVENUE, NEW YORK, N Y. Biophysical studies of macromolecular
interactions (microorganism, human).
ROlHL-1 1876-11 (CVB) GRIGGS, DOUGLAS M, JR, UNIVERSITY OF MISSOURI,
SCHOOL OF MEDICINE, COLUMBIA, MO. Regional myocardial blood flow
and metabolism (dogs, swine).
ROlHL-1 1880-10 (HEM) WHITE, JAMES G, UNIVERSITY OF MINNESOTA. BOX 479
MAYO MEMORIAL BLDG, MINNEAPOLIS, MINN. Physiology and pathology
of blood platelets (human, dogs).
ROIHL-1 1897-11 (PTHA) CORNWELL, DAVID G, OHIO STATE UNIVERSITY, 333
WEST lOTH AVENUE, COLUMBUS, OHIO. Pathogenesis of experimental
atherosclerosis (rabbits, guinea pigs).
ROIHL-1 1901-12 (SGYB) BUCHWALD, HENRY, UNIV OF MINNESOTA HOSPITALS.
BOX 290, MINNEAPOLIS, MINN. Effects of metabolic surgery on the
hyperlipidemias.
ROlHL-1 1901-12 0001 (SGYB) BUCHWALD, HENRY. Effects of metabolic sur-
gery on the hyperlipidemias-Partial ileal bypass (human).
ROIHL-1 1901-12 0004 (SGYB) BUCHWALD, HENRY. Effects of metabolic sur-
gery on the hyperlipidemias -Heal bypass-Cholesterol dynamics studies
(rats, rabbits, dogs).
ROlHL-1 1901-12 0006 (SGYB) BUCHWALD, HENRY. Effects of metabolic sur-
gery on the hyperlipidemias-Drug therapy with ileal bypass (rabbits).
ROlHl-l 1901-12 0009 (SGYB) BUCHWALD, HENRY. Effects of metabolic sur-
gery on the hyperlipidemias-Cholesterol cord blood and family
management program.
R01HL-n901-12 0012 (SGYB) BUCHWALD, HENRY. Effects of metabolic sur-
gery on the hyperlipidemias-lleal bypass-Animal atherosclerosis impli-
cations (pigeons, dogs, rabbits).
ROIHL-1 1901-12 0013 (SGYB) BUCHWALD, HENRY. Effects of metabolic sur-
gery on the hyperlipidemias -Human cholesterol and bile acids dynam-
ics-lleal bypass.
ROlHL-1 1901-12 0014 (SGYB) BUCHWALD, HENRY. Effects of metabolic sur-
gery on the hyperlipidemias-Effect of bypass on gastrin levels (dogs,
human).
ROIHl-1 1901-12 0015 (SGYB) BUCHWALD, HENRY. Effects of metabolic sur-
gery on the hyperlipidemias -Portacaval shunt for cholesterol reduction
(dogs, rabbits).
PROJECT NUMBER AND INVESTIGATOR ADDRESS
534
R0IHL-II90I
R0IHL-n901-
R01HL-U901
R01HL-n901
ROIHl-11906
ROIHL-11907
R01HI-119I9-
R01HI-I194S
R01 HI- 11963
R01HL-I2083
R01HL-12085
ROIHl-12138.
POIHl-12157.
P01HI-121S7
PCIHl-12157
l»01Hl-121S7
P01HI-121S7
POIHl-12157.
P01H1.121S7-
P0tHl-12IS7
P01HI.I21S7
P01HI-121S7
P01H1.12157
P01HI-12IS7-
P01HL-121S7-
R01H1.12174-
R01HI.I2186
R0IHL.122S6
R01HL-12307
R01HL-12322-
P0 1 HI- 12373-
POIHl-12373
P0IHL.12373
POIHl-12373-
P01H1.12373
12 0017 (SGVB) BUCHWAID, HENRY. Effects of metabolic sur
gery on the hyperlipidemias-Membrane permeability, blood viscosity
oxygen uptake-Rheology studies (rabbits).
12 0018 (SGYB) BUCHWAID, HENRY. Effects of metabolic sur
gery on the hyperlipidemias-Jejuno-ileal bypass-Postoperative compli-
cations (human).
-12 0019 (SGYB) BUCHWAID, HENRY. Effects of metabolic sur-
gery on the hyperlipidemias-Cholesterol. bileacids, lipoproteins in
obese humans.
-12 0020 (SGYB) BUCHWAID, HENRY. Effects of metabolic sur
gery on the hyperlipideraias -Jejuno-ileal bypass-Endogenous animal
model of obesity (rats)
-11 (CVA) WHAIEN, WIlllAM J, ST VINCENT CHARITY HOSPITAL
2351 EAST 22ND STREET. CLEVEUND, OHIO. Comparative study of
heart function (cats, rats, hedgehogs, squirrels).
-08 (CVA) WASSERMAN, KARUAAN, HARBOR GENERAL HOSPITAL
1000 WEST CARSON STREET, TORRANCE. CALIF. Mechanisms of
physiological responses to exercise (human, dogs).
■08 (SGYA) WILCOX, BENSON R, UNIVERSITY OF NORTH CAROLINA
DEPARTMENT OF SURGERY, CHAPEL HILL, N C. Pulmonary circulation
in surgical heart disease (human, dogs).
-10 (SGYB) GAUETTI, PIERRE M, BROWN UNIVERSITY BOX G DIV
OF BIOL & MED SCIS, PROVIDENCE, R I. Synthesis of artificial lung
and kidney systems (sheep, mice, swine).
-10 (PTHA) SANDBERG, LAWRENCE B, UNIVERSITY OF UTAH COL-
LEGE OF MEDICINE. SALT LAKE CITY, UTAH. Biochemistry of blood ves-
sel formation and disease (sv»ine).
-11 (CVA) ATABEK, BUIENT H, CATHOLIC UNIVERSITY, OEPT OF
MEXHANICAL ENGINEERING, WASHINGTON, D C. Flow field in aorta and
its major branches (dogs, phantom models).
-10 (MET) EATON, R PHIIIP, UNIVERSITY OF NEW MEXICO OEPT OF
MEDICINE. ALBUQUERQUE. N MEX. Lipoprotein-carbohydrate metabol-
ism (human, rats).
•08 (NTN) JOHNSON, B CONNOR, OKLAHOMA MEDICAL RESEARCH
FDN. 825 NORTHEAST I3TH STREET, OKUHOMA CITY, OKU, Nutri-
tional regulation of enzyme activity (rats, human).
11 (HEPA) JOHNSON, EDWARD A, DUKE UNIVERSITY, BOX 3709,
DURHAM, N C. Functions and mechanisms of cell membrane ion
transport.
■11 0033 (HEPA) lAUF, P K. Functions and mechanisms of cell
membrane ion transport -Immunology aspects of active Na-K transport
in sheep red cell (also human, mice).
■II 0037 (HEPA) JOHNSON, E A. Functions and mechanisms of
cell membrane ion transport -Developing structure of heart cells In tis-
sue culture.
■11 0038 (HEPA) SIMON, S A. Functions and mechanisms of cell
membrane ion transport-Mechanisms and interactions of gases and
ions with bilayer membranes (human).
11 0049 (HEPA) JOHNSON, E A. Functions and mechanisms of
cell membrane ion transport -Ouabain-insensitive cation transport in
duck red cells.
II OOSl (HEPA) MCMANUS, T J. Functions and mechanisms of
cell membrane ion transport-Electron transport in the red cell mem-
brane (human, guinea pigs).
11 0052 (HEPA) JOHNSON, E A. Functions and mechanisms of
cell membrane ion transport -Active electrical properties of the
synthetic strand.
11 0054 (HEPA) JOHNSON, E A. Functions and mechanisms of
cell membrane ion transport-Simulation of electrogenic ion transport
in cardiac muscle
-11 0055 (HEPA) LIEBERMAN, M. Functions and mechanisms of
cell membrane ion transport-Growth and development of synthetic
strand heart cells in culture (chick embryo).
11 0056 (HEPA) HORRES, C R. Functions and mechanisms of cell
membrane ion transport-lsotopic fluxes in synthetic strands of heart
cells (chick embryo).
11 0057 (HEPA) llEBERMAN, M. Functions and mechanisms of
cell membrane ion transport -Electrophysiological investigations of
synthetic strands of heart muscles (rats).
-11 0058 (HEPA) JOHNSON, E A. Functions and mechanisms of
cell membrane ion transport-Ionic and osmotic regulation in toadfish-
-A euryhaline aglomerular teleost.
■11 0060 (HEPA) JOHNSON, E A. Functions and mechanisms of
cell membrane ion transport-Ion transport and electrical properties of
giant-celled aiga
-11 (PHY) HIASTALA, MICHAEL P, UNIVERSITY OF WASHINGTON
MEDICINE DEPARTMENT. SEATTLE. WASH. Ventilation/perfusion dis-
tribution in the lung (human, mammals).
■09 (PHRA) BLINKS, JOHN R, MAYO FOUNDATION, 200 FIRST STREET
SOUTHWEST, ROCHESTER, MINN. Calcium transients in striated
muscle and other cells (mammals, frogs).
-15 (BBCB) STEINHARDT, JACINTO, GEORGETOWN UNIVERSITY
37TH & 0 STREETS, N W, WASHINGTON, D C. Polymerization of sickle-
cell hemoglobin (human).
■08 (CVB) RASHKIND, WILLIAM J, ONE CHILDREN'S CENTER 34TH
ST & CIVIC CENTER BLVO, PHIUDELPHIA, PA. Non-surgical treatment
of congenital heart disease (human, dogs).
-10 (SGYA) DAGGETT, WILLARD M, MASSACHUSEHS GENERAL
HOSPITAL. 32 FRUIT STREET, BOSTON, MASS. Extrinsic factors in-
fluencing myocardial performance (dogs, swine).
■10 (HEP) ROSS, JOHN, JR, UNIV OF CALIFORNIA, SAN DIEGO, DEPT
OF MEDICINE M 013. 6A JOLU. CALIF. Cardiopulmonary physiology
and pathophysiology.
10 0001 (HEP) COVELI, JAMES W. Cardiopulmonary physiology
and pathophysiology -Mechanics of myocardial contraction (dogs, rats,
swine).
10 0002 (HEP) ROSS, JOHN, JR. Cardiopulmonary physiology and
pathophysiology-Determinants of performance of the whole heart
(dogs).
10 0003 (HEP) PETERSON, KIRK L. Cardiopulmonary physiology
and pathophysiology-Myocardial function in man.
10 0005 (HEP) FRIEDMAN, WILLIAM F. Cardiopulmonary physiolo-
gy and pathophysiology-Characterization of fetal and neonatal
myocardium (human, cats).
P01HL-12373-
P01HL-12373-
POIHL-12373
P01HL-12373-
P0IHL-I2373
POIHL-12373
POlHL-12373
POIHL-12373
POIHL-12373
R01HL-1239S
ROIHL-12399-
R01HL-I241S
ROlHL-12421
R01HL-I2486
R01HL-12493-
RO 1HL- 12494-
R01HL-12S24
R01HL-12526
R01HL-12528
R01HL-12530-
R01HL-12S42-
R01HL-125S7
R0IHL-I2S61
R01HL-12564
R01HL-12576-
R01HL-1258S-
R01HL-12607-
R01HL-12611-
R01HL-12614-
R01HL-12647
R01HL-12648
R01HL-12650-
R01HL-12677
R01HL-12684
R01HL-12690-<
R01HL-12711-
R01HL-I27IS-
10 0006 (HEP) STEINBERG, DANIEL. Cardiopulmonary physiology
and pathophysiology-Fatty acid metabolism-Regulation, implications
(human, mammals, birds).
10 0012 (HEP) MAYER, STEVEN E. Cardiopulmonary physiology
and pathophysiology-Biochemistry of the sympathetic nervous system
(rats, rabbits, pigeons).
10 0013 (HEP) KARLINER, JOEL S. Cardiopulmonary physiology
and pathophysiology -Effects of cardiovascular drugs on left ventricu-
lar function (dogs).
10 0014 (HEP) COVELL, JAMES W. Cardiopulmonary physiology
and pathophysiology-Analog digital computation and simulation facili-
ty.
-10 0015 (HEP) COVELL, JAMES W. Cardiopulmonary physiology
and pathophysiology-Cine angiographic-hemodynamic facility.
■ 10 0016 (HEP) BLOOR, COLIN M. Cardiopulmonary physiology and
pathophysiology-Histology-histochemistry-Gough laboratory.
■10 0018 (HEP) MAYER, STEVEN E. Cardiopulmonary physiology
and pathophysiology-Biochemistry laboratory.
10 0019 (HEP) FRANKLIN, DEAN. Cardiopulmonary physiology and
pathophysiology-Free ranging animal facility.
10 0020 (HEP) PETERSON, KIRK L. Cardiopulmonary physiology
and pathophysiology-Hospitalization and patient care.
10 (BBCA) SCHAEFER, WILLIAM P, CALIFORNIA INST OF
TECHNOLOGY, 1201 EAST CALIFORNIA BLVD, PASADENA, CALIF. X-ray
study of oxygen-carrying cobalt complexes.
13 (NTN) GEVER, ROBERT, HARVARD SCHOOL OF PUB HLTH 665
HUNTINGTON AVENUE. BOSTON, MASS. Specific fatty acids' and
cholesterol metabolism (gerbils, rats).
■10 (CVA) BISHOP, VERNON S, UNIVERSITY OF TEXAS, 7703 FLOYD
CURL DRIVE, SAN ANTONIO, TEX. Evaluation of left vent.icular (unc-
tion (dogs, rabbits)
10 (CVA) GREGA, GEORGE J, MICHIGAN STATE UNIVERSITY
GILTNER HALL, EAST LANSING, MICH. Pathophysiology of circulatory
shock (dogs, baboons).
10 (CVA) SOMMER, JOACHIM R, DUKE UNIVERSITY, DEPARTMENT
OF PATHOLOGY, DURHAM, N C. Structure-function correlation in the
atrium (rabbits).
10 (CVA) INTAGLIETTA, MARCOS, UNIV OF CALIFORNIA,, LA
JOLLA, CALIF. Bioengineering analysis of microvascular function (cats
rabbits).
10 (CVA) FUNG, YUAN-CHENG B, UNIV OF CALIFORNIA, SAN
DIEGO, LA JOLLA, CALIF. Continuum mechanics in biophysics (human
animals).
-10 (BBCA) NOBLE, ROBERT W, VETERANS ADMINISTRATION HOSP
3495 BAILEY AVENUE, BUFFALO, N Y. Reaction of hemoglobin with
ligands and antibodies (human, carp).
■09 (BBCB) SPIRO, THOMAS G, PRINCETON UNIVERSITY DEPART-
MENT OF CHEMISTRY, PRINCETON, N J. Raman spectra of heme
proteins and related molecules.
•10 (BBCB) WADE, CHARLES G, UNIVERSITY OF TEXAS, CHEMISTRY
DEPARTMENT, AUSTIN, TEX. NMR relaxation of liquid crystal systems
10 (CVA) BRISCOE, WILLIAM A, CORNELL UNIVERSITY. 1300 YORK
AVENUE. NEW YORK, N Y. Emphysema-Respiratory function in disease
(human, dogs, rats).
•07 (TEC) VLAO, PETER, CHILDREN'S HOSPITAL, 219 BRYANT STREET,
BUFFALO, N Y. Natural history, congenital heart defects -Joint study
(human).
-09 (PTHA) ALBERT, ERNEST N, GEORGE WASHINGTON UNIVERSITY
ROSS HALL, ROOM 426, WASHINGTON, D C. Effects of steroids and
pregnancy on arteries and veins (guinea pigs).
-II (PTHA) CARNES, WILLIAM H, UNIVERSITY OF CALIFORNIA
CENTER FOR HEALTH SCIENCES, LOS ANGELES, CALIF. Cardiovascular
studies on copper deficiency (swine).
■09 (AFY) SMITH, EDWARD J, UNION UNIVERSITY, ALBANY MEDICAL
COLLEGE, ALBANY, N Y. Control of respiration and blood gases
(human, dog).
■10 (BIO) KING, TSOO E, S U N Y - AT ALBANY, 1400 WASHINGTON
AVENUE, ALBANY, N Y. Bioenergetics apparatus in heart mitochondria
10 (BIO) HARRISON, JOHN H, UNIVERSITY OF NORTH CAROLINA
DEPARTMENT OF CHEMISTRY, CHAPEL HILL, N C. Structural properties
of malate dehydrogenase (swine).
10 (CVB) MILNOR, WILLIAM R, JOHNS HOPKINS UNIVERSITY 725
NORTH WOLFE STREET, BALTIMORE, MD. Dynamics of pulsatile 'blood
flow (human, dogs, rats).
10 (CVB) BURGESS, MARY J, UNIVERSITY OF UTAH INTERNAL
MEDICINE DEPARTMENT, SALT LAKE CITY, UTAH. Basic and clinical
studies of the ST-T deflection (human, dogs).
•09 (CVB) HARRIS, PATRICK D, UNIVERSITY OF MISSOURI
RESEARCH PARK, COLUMBIA. MO. Microcirculatory control mechanisms
and hypertension (bats, rats).
■08 (PHRA) LEVIN, JEROME A, MEDICAL COLLEGE OF OHIO POST
OFFICE BOX 6190. TOLEDO, OHIO. Inactivation of norepinephrine in
vascular tissue.
•09 (PHRA) GITLOW, STANLEY E, MT SINAI SCH OF MED S U N Y
5TH AVENUE AND lOOTH STREET, NEW YORK, N Y. Catecholamine
metabolism in hypertensive diseases (human).
•08 (PTHA) KUHN, CHARLES, WASHINGTON UNIVERSITY DEPART-
MENT OF PATHOLOGY. ST LOUIS. MO. Environmental pathobiology of
the lung (hamsters, rats).
■10 (SGYA) ITSKOVITZ, HAROLD D, MILWAUKEE COUNTY GENERAL
HOSP. 8700 WEST WISCONSIN AVENUE, MILWAUKEE. WIS. Surgical
physiologic studies of isolated kidneys (dogs, rats)
•09 (CVB) FITZ, ANNETTE E, VETERANS ADMINISTRATION HOSP, IOWA
CITY, IOWA. Angiotensin I and converting enzyme in hypertension
(human, primates, dogs).
09 (CVA) FRONEK, ARNOST, UNIV OF CALIFORNIA, SAN DIEGO
MAIL M005, U JOLU, CALIF. Systemic and local vascular adjustment
in shock (monkeys, cats).
■09 (COM) MIRSKY, ISRAEL, PETER BENT BRIGHAM HOSPITAL 721
HUNTINGTON AVENUE. BOSTON, MASS. Mathematical approach to car-
diovascular mechanics (human, animals).
10 (RAD) THURSTONE, FREDRICK L, DUKE UNIVERSITY. BIOMEDI-
CAL ENGINEERING DEPT, DURHAM, N C. Dynamic cardiovascular mea-
surement using ultrasound.
535
PROJECT NUMBER AND INVESTIGATOR ADDRESS
fOIHl-13738-IO (HiPA) HOFFMAN, BRIAN F, COLUMBIA UMVeRSITY. 630 WEST
I68TH. NEW YORK. N Y Physiologic phaimacology and Its clinical ap
plications
P01Hl-ia73a-IO 000) (HEPA) OIARDINA, EISA ORACE V. Physiologic phai
macology and ils clinical applications Clinical pharmacology of car
dioactive diugs (human)
MIHl-ia73S-IO 0035 (HEPA) REIFFEl, J A. Physiologic pharmacology and its
clinical applications Function and dysfunction ol the sinoatrial node
(human)
POIHl-13738-IO 0042 (HEPA) WANG. S C. Physiologic pharmacology and its
clinical applications Centrogenic cardiac arrhythmias (cats)
POIHl-12738-10 0044 (HEPA) WELD, F M. Physiologic pharmacology and its
clinical applications- Cardioactive drugs and electrophysiological pro-
perties ol cardiac cells (sheep)
P0IHIO2738-I0 006S (HEPA) SIMPSON, LANCE L. Physiologic pharmacology
and Its clinical applications-Psychotheropeutic drugs and car
diovascular system (human, rats)
POlHL-12738-10 0069 (HEPA) CHIEN, SHU. Physiologic pharmacology and its
clinical applications -Blood rheology in coronary heart disease (dogs)
P01HL-I2738-10 0071 (HEPA) BREGMAN, DAVID. Physiologic pharmacology
and Its clinical applications- lABP patient management m ventricular
power failure (human)
P01HL-12738-I0 0076 (HEPA) ROSEN, MICHAEL R. Physiologic pharmacology
and its clinical applications-Pediatric cardiac electrophysiology and
pharmacology (human, dogs).
P01HL-I2738-10 0080 (HEPA) WIT, A L. Physiologic pharmacology and its clinical
applications- Electrophysiology of cardiac muscle in the mitral valve
(monkeys).
P01HL-12738-tO 0081 (HEPA) WIT, A L. Physiologic pharmacology and its clinical
applications-Uitrastructural and electrophysiologic alteration of
myocardium (human, dogs).
P01HL-I2738-I0 0092 (HEPA) PARODI, EDUARDO N. Physiologic pharmacology
and Its clinical applications -Subendocardial ischemia following open
heart surgery (human).
P01HL-12738-10 0094 (HEPA) SPOTNIT2, HENRY H. Physiologic pharmacology
and its clinical applications -Ventricular function and structure
(human, dogs).
P01HL-I2738-10 0098 (HEPA) SPOTNITZ, HENRY H. Physiologic pharmacology
and its clinical applications -Skeletal muscle support of the chroni-
cally failing heart (dogs).
POIHl-12738-10 0107 (HEPA) ROSEN, MICHAEL R. Physiologic pharmacology
and its clinical applications -Blood superfused cardiac fibers (dogs).
POIHL-12738-10 0108 (HEPA) ROSEN, MICHAEL R. Physiologic pharmacology
and its clinical applications-Developmental electrophysiology and
pharmacology (human, animals).
roiHL-12738-10 0109 (HEPA) KIRSTEN, EDWARD B. Physiologic pharmacology
and its clinical applications -Effects of calcium blockers on skeletal
and cardiac muscle (cats).
POIHL-12738-10 0110 (HEPA) HOFFMAN, BRIAN F. Physiologic pharmacology
and its clinical applications-Physiology and pharmacology of arr-
hythmias (dogs).
POIHL-12738-10 0111 (HEPA) WANG, H H. Physiologic pharmacology and its
clinical applications -Cardiovascular pharmacology (dogs)
POIHL-12738-10 0114 (HEPA) SAWYER, W H. Physiologic pharmacology and its
clinical applications-Receptor specificites and metabolism of neu-
rohypophysial hormones (rats).
POIHL-12738-10 0117 (HEPA) BIGGER, J THOMAS, JR. Physiologic phar-
macology and its clinical applications -Ventricular arrhythmias in
ischemic heart disease (human).
POIHL-12738-10 0122 (HEPA) HABAL, SALEM. Physiologic pharmacology and its
clinical applications-Coronary perfusion of beating and fibrillating
hearts (dogs).
POIHL-12738-10 0123 (HEPA) BREGMAN. DAVID. Physiologic pharmacology
and its clinical applications-Ventricular assistance and preservation
(human, dogs).
POIHL-12738-10 0124 (HEPA) WELLS, W. Physiologic pharmacology and its clini-
cal applications-Counterpulsation on myocardial ischemia measured
by carbon dioxide tension (dogs).
POIHL-12738-10 0127 (HEPA) KRONGRAD, EHUD. Physiologic pharmacology
and its clinical applications-Cardiac electrical activity (human,
animals).
POIHL-12738-10 0128 (HEPA) HOFFMAN, BRIAN F. Physiologic pharmacology
and its clinical applications-Recording electrograms from specialized
cardiac tissues (human, dogs).
POIHL-12738-10 0129 (HEPA) SAWYER. W H. Physiologic pharmacology and its
clinical applications-Receptor specificities and metabolism of
vasopressin analogs.
POlHl-12738-10 0130 (HEPA) SPOTNITZ. H. Physiologic pharmacology and its
clinical applications -Compatibility enhancement during cardiac al-
lografting (dogs).
POIHL-12738-IO 0131 (HEPA) KRONGRAD. EHUD. Physiologic pharmacology
and its clinical applications-Evaluation of intracardiac shunts by con-
trast echocardiography (dogs).
POIHL-12738-10 0132 (HEPA) HOFFMAN. BRIAN F. Physiologic pharmacology
and its clinical applications-Coronary occlusions and arrhythmias
(dogs).
POIHL-12738-10 0133 (HEPA) AVERY. G JAMES. III. Physiologic pharmacology
and its clinical applications-Pharmacologic antagonism of beta-adre-
nergic blockade (dogs).
POIHL-12738-10 0134 (HEPA) TRINER. L. Physiologic pharmacology and its clini-
cal applications-Adenylate cyclase and cAMP phosphodiesterase in
cardiac development (dogs).
POIHL-12738-10 0135 (HEPA) ROBINSON. RICHARD. Physiologic pharmacology
and its clinical applications-Myocardial cells in tissue culture (rats,
chick embryo).
POIHL-12738-10 0136 (HEPA) WIT. A L. Physiologic pharmacology and its clinical
applications-.
R01HL-I2740-I0 (PHRA) WITIAK, DONALD T. COLLEGE OF PHARMACY. 500 WEST
12TH AVENUE, COLUMBUS, OHIO. Hypocholesterolemic agents-
Stereochemistry (rats).
ROIHl-1 2745-10 (PC) POPJAK, GEORGE J, UNIVERSITY OF CALIFORNIA, DEPT OF
BIOLOGICAL CHEMISTRY, LOS ANGELES. CALIF. Enzymes and inhibitors
of cholesterol biosynthesis (rats, human, swine).
R01HL-I276009 (BBCB) CADENHEAO, DAVID A, S U N Y Al BUFFAIO. OE
PARIMENI Of CHEMISIRY. BUFFALO. N Y Surfict »ludi«» ol mem
brane lipids and proteins
ROIHL-12766-09 (CVB) WOLINSKY, HARVIY, ALBERT EINSTEIN COIL OF MED.
1300 MORRIS PARK AVfNUt. BRONX. N Y Structure function relation
ol blood vessels (rals, monkeys)
ROIHL-1 2774-08 (CVA) KAVALER, FREDERIC, S U N Y DOWNSIAIE MED CIR.
450 CLARKSON AVENUE, BROOKLYN, N Y Ionic coupling in activation
ol cardiac muscle (Irogs, guinea pigs)
ROIHl-l 2775-08 (CVB) ROSENBLUM, WIUIAM I, VIRGINIA COMMONWEAIIH
UNIV. BOX i;, OIV OF NEUROPATHOLOGY . RICHMOND. VA Cerebral
microciiculation (mice)
R01HL-12777-09 (SGYB) DAGGETT, WILLARD M, MASSACHUSEHS GENERAL
HOSP. FRUII STREET. BOSTON, MASS Mechanisms in cardiac per
lormance (dogs, human)
ROIHl-12792-09 (PHY) DULING. BRIAN R, UNIVERSITY OF VIRGINIA, DEPARTMENT
OF PHYSIOLOGY, CHARLOnESVILLE, VA Local control ol the microcir-
culation (hamsters, rats)
R01HL-I2820-09 (HEM) JACKSON, CRAIG M, WASHINGTON UNIVERSITY, 660
SOUTH EUCLID AVENUE, SI LOUIS, MO In vitro regulation of prothrom-
bin activation
ROIHL-1 2827-08 (GMB) SLOTKOFF, LAWRENCE M, GEORGETOWN UNIVERSITY
HOSPITAL, 3800 RESERVOIR ROAD, N W. WASHINGTON, D C Regula-
tion of sodium excretion (dogs, rats)
ROIHL-1 2833-09 (EDC) MITTMAN, CHARLES, CITY OF HOPE MEDICAL CENTER.
1500 EAST DUARTE ROAD. DUARTE. CALIF Genetic and environmental
influences on lung disease (human).
ROIHL-1 2839-09 (SGYA) SUTERA, SALVATORE P, WASHINGTON UNIVERSITY. BOX
1185. LINDELL/SKINKER BLVD. ST LOUIS, MO Flow, transport and
membrane phenomena in blood (human).
ROIHL-1 2869-09 (MET) CHOBANIAN, ARAM V, BOSTON UNIVERSITY, 80 EAST
CONCORD STREET, BOSTON, MASS. Arterial metabolism, diabetes and
atherogenesis (rats, rabbits).
ROIHl-1 2879-09 (CVA) CHINARD, FRANCIS P, NEW JERSEY MEDICAL SCHOOL,
100 BERGEN STREET. NEWARK, N J. Pulmonary transport and metabol-
ism in vivo.
ROIHL-1 2879-09 0002 (CVA) RITTER, A B. Pulmonary transport and metabolism
in vivo -Osmotic compartmental model of barrier exchange.
ROIHL-1 2879-09 0005 (CVA) CHINARD, FRANCIS P. Pulmonary transport and
metabolism in vivo-Glucosc transport by pulmonary endothelium and
epithelium (dogs).
ROIHL-1 2879-09 0006 (CVA) CHINARD, FRANCIS P. Pulmonary transport and
metabolism in vivo-The missing sodium.
ROIHL-1 2879-09 0007 (CVA) CHINARD, FRANCIS P. Pulmonary transport and
metabolism in vivo-Etfects of temperature changes on pulmonary
transport.
ROIHL-1 2879-09 0008 (CVA) CHINARD, FRANCIS P. Pulmonary transport and
metabolism in vivo-Stop-flow technique for permeability measure-
ments.
R01HL-1 2879-09 0010 (CVA) DEFOUW, D. Pulmonary transport and metabolism
in vivo-Lung morphometry in control and edematous lungs (dogs).
ROIHL-1 2879-09 0011 (CVA) GARRICK, R A. Pulmonary transport and metabol-
ism in vivo-Membrane characteristics of lung cells (human, animals).
ROIHL-1 2944-09 (HEM) VALENTINE, WILLIAM N, UNIVERSITY OF CALIFORNIA,
MEDICINE DEPARTMENT, LOS ANGELES, CALIF. Enzymatic and
biochemical studies on blood cells (human).
ROIHL-1 2971 -1 5 (MCHA) SHAMMA, MAURICE, PENNSYLVANIA STATE UNIVERSI-
TY, 152 DAVEY LABORATORY, UNIVERSITY PARK, PA. Reactions of alko-
loids and their analogs.
ROIHL-1 2972-09 (HEM) SMITH, JOSEPH E, KANSAS STATE UNIVERSITY, BURT
HALL, MANHATTAN, KANS. Glutathione deficiency in red cells (sheep,
dogs).
ROIHL-1 2974-10 (CVA) CHINARD, FRANCIS P, NEW JERSEY MEDICAL SCHOOL.
100 BERGEN STREET, NEWARK, N J. Tracer kinetics, flows and masses
in body organs (human, dogs).
ROIHl-l 2990-09 (GMB) SHARE, LEONARD, UNIVERSITY OF TENNESSEE. 894
UNION AVENUE, MEMPHIS, TENN. Control of antidiuretic hormone
secretion and metabolism (dogs, rats, rabbits).
ROIHl-1 2994-09 (HEM) MASOUREDIS, SERAFEIM P, UNIV OF CALIFORNIA, SAN
DIEGO. M-012, LA JOLLA, CALIF. The Rh complex of red cells (human).
ROIHL-1 2997-07 (CVB) HARRISON, CARLOS E, JR, MAYO FOUNDATION. 200
FIRST STREET, S W, ROCHESTER, MINN. Myocardial defects induced by
potassium depletion (human, rats..
ROIHL-1 3028-09 (MET) NEELV. JAMES R, MILTON S HERSHEY MEDICAL CTR, 500
UNIVERSITY DRIVE, HERSHEY, PA. Regulation of myocardial fatty acid
metabolism (rats).
ROIHL-1 3029-09 (MET) MORGAN. HOWARD E. MILTON S HERSHEY MED
CENTER, DEPARTMENT OF PHYSIOLOGY. HERSHEY. PA. Metabolic regu-
lation of sugar transport (pigeons, rats).
ROIHL-1 3035-08 (BIO) SHORE, JOSEPH D, HENRY FORD HOSPITAL, 2799 WEST
GRAND BOULEVARD, DETROIT, MICH. Heart mitochondrial malate
dehydrogenase regulation.
ROIHL-1 3036-08 (CVB) MOSCHOS, CHRISTOS B, NEW JERSEY MEDICAL SCHOOL.
100 BERGEN STREET, NEWARK, N J Coronary thrombosis-Effects on
myocardium and in vivo detection (dogs, monkeys) ,
P01HL-I3108-09 (HEPA) STINSON. EDWARD B, STANFORD UNIVESITY. DEPT OF
CARDIOVASCULAR SURGERY, STANFORD, CALIF. Clinical heart trans-
plantation.
POIHL-13108-09 0001 (HEPA) STINSON. EDWARD B. Clinical heart transplan-
tation-Therapy and prognosis (human).
POIHL-13108-09 0002 (HEPA) BIEBER. CHARLES P. Clinical heart transplanta-
tion-Preoperative immunologic studies of cardiac recipients.
POIHL-13108-09 0003 (HEPA) BILLINGHAM. MARGARET T. Clinical heart
transplantation -Endomyocardial biopsy pathology.
POIHL-13108-09 0008 (HEPA) SCHROEDER, JOHN. Clinical heart transplanta-
tion-Physiology and pharmacology of the transplanted human heart.
POIHL-13108-09 0009 (HEPA) GRUMET, F CARL. Clinical heart transplantation-
B cell alloantigens in cardiac allograft compatibility (human).
POIHL-13108-09 0010 (HEPA) BIEBER, CHARLES P. Clinical heart transplanta-
tion-Serum factors inhibiting lymphocyte responses in MLC (human,
bush babies).
POIHL-13108-09 0011 (HEPA) BIEBER, CHARLES P. Clinical heart transplanta-
tion-Humoral and cellular kinetics of allograft rejection (human).
POIHL-13108-09 0012 (HEPA) BIEBER, CHARLES P. Clinical heart transplanta-
tion-Human T cell sheep erythrocyte receptors.
PROJECT NUMBER AND INVESTIGATOR ADDRESS S36
POIHl-1 3 108-09 0013 (HEPA) BIEBER, CHARLES P. Clinical heart transplanta
tion-Cardiomyopathic lymphocyte responsiveness to cultured endotheli-
um.
POlHl.13108-09 0014 (HEPA) HARBURY, CHRISTINA B. Clinical heart trans
plantation-Platelets and coagulation in accelerated graft coronary
atherosclerosis
P01HI-I310B-09 0015 (HEPA) BIEBER, CHARLES P. Clinical heart transplanta
tion-Antithymocyte globulin analysis and clinical effects.
POlHL-13108-09 0016 (HEPA) STROBER, SAM. Clinical heart transplantation -
Total lymphoid irradiation for immune response (dogs).
POIHL-13108-09 0017 (HEPA) MASON, JAY W. Clinical heart transplantation-
Electrophysiology of the transplanted denervated human heart
P01HL-13108.09 0018 (HEPA) MASON, JAY W. Clinical heart transplantation-
Electrophysiologic studies of cardiac drugs in the denervated heart
POIHL-13108-09 0019 (HEPA) MASON, JAY W. Clinical heart transplantation -
Effect of autonomic nervous system on arrhythmias (human).
POIHL-13108-09 0020 (HEPA) RICCI, DONALD R. Clinical heart transplantation
-Autonomic neural studies in the denervated heart (human).
POIHL-13108-09 0021 (HEPA) RICCI, DONALD R. Chnical heart transplantation-
-Autonomic reflex regulation of ventricular function (human).
POIHL-13108-09 0022 (HEPA) RICCI, DONALD R. Clinical heart transplantation-
-Studics on cardiac receptors (human).
POIHL-13108-09 0023 (HEPA) SCHROEDER, JOHN S. Clinical heart transplan-
tation-Adaptive mechanisms of the denervated heart (human).
POIHL-13108-09 0024 (HEPA) SCHROEDER, JOHN S. Clinical heart transplan-
tation-Response of denervated heart to stress -Noninvasive (human)
R01HL-I3134-07 (CVA) NAIR, PANKAJAM, ST VINCENT CHARITY HOSPITAL 2351
EAST STREET, CLEVELAND, OHIO. Mechanism of chemoreceptor
discharge (cats).
ROIHl-13157-09 (BBCA) IBERS, JAMES A, NORTHWESTERN UNIVERSITY DEPART-
MENT OF CHEMISTRY, EVANSTON, ILL. Molecular oxygen carriers -
Synthesis, structure, bonding.
R01HL-13160-08 (HEM) FENTON, JOHN W, II, NEW YORK STATE DEPT OF
HEALTH. EMPIRE STATE PLAZA, NEW YORK, N Y. Human thrombin
(also cattle).
ROIHL-13164-07 (BBCA) BUCCI, ENRICO, UNIVERSITY OF MARYLAND 660 WEST
REDWOOD STREET, BALTIMORE, MD. Interaction of the alpha and beta
chains of human hemoglobin.
ROIHL-13172-10 (SGYB) PETERS, RICHARD M, UNIVERSITY HOSPITAL, 225 WEST
DICKINSON STREET, SAN DIEGO, CALIF. Post-trauma lung mechanics
and fluid exchange (human, dogs, monkeys).
R01HL-1 31 87-09 (PHRA) GEBBER, GERARD L, MICHIGAN STATE UNIVERSITY
DEPT OF PHARMACOLOGY, EAST LANSING, MICH. Central neural control
of cardiovascular function (cats).
ROIHL-1 3 193-09 (SGYB) RUSH, BENJAMIN F, JR, NEW JERSEY MEDICAL
SCHOOL, 100 BERGEN STREET, NEWARK, N J. Pathophysiology of post-
traumatic and shock states (rodents, dogs).
R01HL-13198-21 (HEM) WAUGH, DAVID F, MASSACHUSETTS INST OF TECH 77
MASSACHUSEHS AVENUE, CAMBRIDGE, MASS. Blood coagulation-
Physico-chemical properties (human, cattle),
ROIHL-1 3233-08 (AFY) HILDEBRANDT, JUDITH R, VIRGINIA MASON RESEARCH
CTR, 1000 SENECA STREET, SEAHLE, WASH. Cardiorespiratory control
in exercise (human).
ROIHL-1 3237-09 (PHY) LEE, PING, WEST VIRGINIA UNIVERSITY, DEPT OF PHY &
BIOPHYSICS, MORGANTOWN, W VA. Erythrocytes during earty develop-
ment (human, animals).
R01HL-13256-08 (PHY) VIDAVER, GEORGE A, UNIVERSITY OF NEBRASKA DE-
PARTMENT OF CHEMISTRY, LINCOLN, NEBR, Amino acid transport by
red cell membranes (pigeons).
R01HL-I33S7-09 (SGYA) MERIN, ROBERT G, UNIVERSITY OF ROCHESTER 601
ELMWOOD AVENUE, ROCHESTER, N Y. Inhalation anesthesia on
myocardial metabolism (dogs, swine, human).
POIHL-13262-07 (HEPA) HOLLANDER, WILLIAM, BOSTON UNIVERSITY SCHOOL
OF ME, 80 EAST CONCORD STREET, BOSTON, MASS. Arterial wall in
atherosclerosis.
POIHL-1 3262-07 0011 (HEPA) HOLLANDER, WILLIAM. Arterial wall in atheros-
clerosis-Role of hypertension in atherosclerosis (human, monkey dog)
POIHL-13262-07 0012 (HEPA) FRANZBLAU, CARL. Arterial wall in atherosclero-
sis-Characterization of connective tissue components (animals)
P0IHUI3262-07 0015 (HEPA) KAGAN, HERBERT M. Arterial wall in atheros
clerosis-Crosslinkage biosynthesis in aortic elastin and collagen
(animals).
P01HL.1 3262-07 0016 (HEPA) KRAMSCH, DIETER M. Arterial wall in atheros-
clerosis-Lipids in elastin preparations from atherosclerotic plaques
(human, animals).
P01HL.13262-07 0018 (HEPA) SCHMID, KARL. Arterial wall in atherosclerosis -
Vasoactive factors of human plasma.
POIHL-13262-07 0022 (HEPA) DEYKIN, DANIEL. Arterial wall in atherosclerosis-
Mechanisms of platelet prostaglanoin formation.
POIHL-13262-07 0023 (HEPA) FOSTER, JUDITH. Arterial wall in atherosclerosis-
Isolation and characterization of soluble elastin
POIHL-13262-07 0024 (HEPA) LAING, RONALD A. Arterial wall in atherosclero
sis-Scrial ocular changes in arteriosclerosis and hypertension.
POIHL-13262-07 0025 (HEPA) SMALL, DONALD. Arterial wall in atherosclerosis
Phospholipid and cholesterol esters.
R01HL-13302-09 (MET) ONTKO, JOSEPH A, OKLAHOMA MEDICAL RESEARCH FDN
825 N W I3TH STREET, OKLAHOMA CITY, OKLA. Uptake and metabol-
ism of lipids by the liver (rats).
ROIHL-I3306-08 (PHRA) TSIEN, RICHARD W, YALE SCHOOL OF MEDICINE, 333
CEDAR STREET, NEW HAVEN, CONN. Pharmacological control of car-
diac membrane currents (cattle, rabbits).
R01HL-133IS-08 (PHRA) GILLIS, CHARLES N, YALE UNIVERSITY, 333 CEDAR
STREET. NEW HAVEN, CONN, Disposition of vasoactive hormones in
mammalian lung (rats, rabbits, human).
ROIHL-1 3323-08 (CVB) HEBERT, LEE A, MILWAUKEE COUNTY GEN HOSPITAL WEST
WISCONSIN AVENUE, MILWAUKEE, WIS. Intrarenal pressure and renal
function (human, dogs).
POIHL-13330-08 (HEP) DEBAKEY, MICHAEL E, BAYLOR COLLEGE OF MEDICINE
1200 MOURSUND AVENUE, HOUSTON, TEX. Mechanical circulatory sup-
port.
POIHl.13330-08 0031 (HEP) OBANNON, WILLIAM. Mechanical circulatory sup
port-Hemodynamics of cardiac prosthesis.
POIHL.13330-08 0034 (HEP) NOON, GEORGE P. Mechanical circulatory sup
port-In vivo test and evaluation of left ventricular bypass pumps
(human, cattle).
POIHL-13330-08 0056 (HEP) ESKIN, S G. Mechanical circulatory support-Blood
compatibility linings (calves).
POIHL-13330-08 0059 (HEP) CHIMOSKEY, JOHN E. Mechanical circulatory sup-
port-Physiologic evaluation of circulatory assistance (cattle).
POIHL-13330-08 0062 (HEP) DEBAKEY, MICHAEL E. Mechanical circulatory sup-
port-CORE facilities.
R01HL-I3336-09 (HEM) KARPATKIN, SIMON, NEW YORK UNIVERSITY. 550 FIRST
AVENUE, NEW YORK, N Y. Biochemistry and physiology of human
platelets.
ROIHL-1 3339-08 (PHRA) PAPPANO, ACHILLES J, UNIV OF CONN HEALTH CNTR,
DEPT OF PHARMACOLOGY. FARMINGTON. CONN. Pharmacology of
developing cardiac tissues (chick embryo).
R01HL-1334I-06 (SGYB) WITTE, CHARLES L, ARIZONA MEDICAL CENTER, 1501
NORTH CAMPBELL AVENUE, TUCSON, ARIZ. Lymph-An indication of
splanchnic tissue respiration (dogs, human, rats).
ROIHL-1 3349-06 (PHY) SLEATOR, WILLIAM W, UNIVERSITY OF ILLINOIS, 524
BURRILL HALL, URBANA. ILL. Analysis of activation process in heart
muscle (guinea pigs, rabbits, human).
ROIHL-1 3375-09 (CVA) DAVIS, LARRY D, UNIVERSITY OF WISCONSIN, 470 NORTH
CHARTER STREET, MADISON, WISC. Cellular potential changes causing
cardiac arrhythmias (dogs).
ROIHL-13399-16 (BBCB) PEISACH, JACK, ALBERT EINSTEIN COLL OF MED, 1300
MORRIS PARK AVENUE, BRONX, N Y. Heme protein structure and func-
tion (human, horse, plants, bacteria).
ROIHL-1 3405-09 (MET) LONGMORE, WILLIAM J, ST LOUIS UNIVERSITY, 1402 S
GRAND BOULEVARD, ST LOUIS, MO. Regulation of lipid metabolism in
the lung (rats).
ROIHL-1 3408-05 (CVB) IWAI, JUNICHI, BROOKHAVEN NATIONAL LABORATORY,
MEDICAL RESEARCH CENTER, UPTON, N Y. Environmental-genetic in-
teractions in hypertension (rats).
R01HL-I34I2-I7 (MCHB) BASOLO, FRED, NORTHWESTERN UNIVERSITY. DEPART-
MENT OF CHEMISTRY. EVANSTON, ILL. Synthetic oxygen carriers.
ROIHL-1 3423-08 (HEM) CASTELLINO, FRANCIS J, UNIVERSITY OF NOTRE DAME.
DEPARTMENT OF CHEMISTRY, NOTRE DAME, IND. Structure-function
studies of plasminogen and plasmin (human).
ROIHL-1 3426-09 (SGYA) PIERCE, WILLIAM S, PENNSYLVANIA STATE UNIVERSITY,
DEPARTMENT OF SURGERY. HERSHEY. PA. Left ventricular bypass for
myocardial infarction (cattle, human).
ROIHL-1 3427-09 (CVB) GIUAORE, JOSEPH P, UNIVERSITY OF NEBRASKA. 42ND
AND DEWEY. OMAHA, NEBR. Neural control of blood volume (monkeys,
dogs).
ROIHL-1 3437-09 (CVB) GORE, ROBERT W, UNIVERSITY OF ARIZONA, DEPART-
MENT OF PHYSIOLOGY, TUCSON, ARIZ. Physical and mechanical
parameters in the microcirculation (animals).
ROIHL-1 3454-08 (CVB) CORLEY, KARL C, JR, MEDICAL COLLEGE OF VIRGINIA,
MCV STATION, BOX 608, RICHMOND, VA. Behavioral stress and cardio-
myopathy (monkeys, cats).
ROIHL-1 3466-08 (SGYB) SCHWARTZ, SEYMOUR I, UNIVERSITY OF ROCHESTER,
601 ELMWOOD AVENUE, ROCHESTER, N Y. Pulmonary platelets in
shock, trauma and embolization (dogs, pigs, rats).
POIHL-1 3480-09 (HEP) ABILDSKOV, J A, UNIVERSITY OF UTAH MEDICAL CEN. 50
NORTH MEDICAL DRIVE, SALT LAKE CITY, UTAH. Cardiac elec-
trophysiology.
POIHL-1 3480-09 0017 (HEP) ABILDSKOV, J A. Cardiac electrophysiology-Body
surface potential mapping (human, dogs).
POIHL-1 3480-09 0026 (HEP) MILLAR, KAY. Cardiac electrophysiology-Neural in-
fluences on cardiac electrophysiology and contraction (dog, cat).
P01HL-1 3480-09 0028 (HEP) VINCENT, G MICHAEL. Cardiac electrophysiology-
Stress electrocardiography (human, dogs).
POIHL-1 3480-09 0032 (HEP) BURGESS, MARY JO. Cardiac electrophysiology-
Cardiac activation sequence (dogs).
POIHL-1 3480-09 0042 (HEP) LUX, ROBERT L. Cardiac electrophysiology -Computer
modeling of arrhythmias.
R01HL-13S31-06 (BBCB) HOFFMAN, BRIAN M, NORTHWESTERN UNIVERSITY DE-
PARTMENT OF CHEMISTRY. EVANSTON, ILL. Coboglobins-Cobalt sub-
stituted myo- and hemoglobins.
ROIHL-1 3567-06 (PHY) OMACHI, AKIRA, UNIVERSITY OF ILLINOIS. 901 SOUTH
WOLCOn STREET. CHICAGO, ILL. Ion transport across cell membranes
(human).
ROIHL-13581-11 (MCHB) TRAYLOR, TEDDY G, UNIV OF CALIFORNIA. SAN DIEGO,
LA JOLLA, CALIF. Reactions of oxygen with heme proteins
ROIHL-1 3585-05 (HEM) SCHWARTZ, JOEL M, CONEY ISUND HOSPITAL 2601
OCEAN PARKWAY, BROOKLYN, N Y. Heterogeneity of NADH
metheraoglobin reductase (human).
ROIHL-1 3587-06 (MCHA) TURCOTTE, JOSEPH G, UNIVERSITY OF RHODE ISLAND
LOWER COLLEGE ROAD, KINGSTON, R I. Synthesis of renin inhibitors
and analog phosphatides (rats).
ROIHL-1 3595-08 (CVB) KRAKOFF, LAWRENCE R, C U N Y - MT SINAI SCH OF
MED, Finn AVENUE & ICOTH STREET, NEW YORK, N Y. Renin and
vascular hyper-reactivity in hypertension (human, rats)
R01HL-I3596-07 (CVA) MEYER, EDWARD C, MERCY CATHOLIC MEDICAL CENTER
UNSDOWNE AVE & BAILY ROAD, DARBY, PA. Clearance of plasma
proteins from alveoli.
R01HL-13619-09 (BIO) MASTERS, BETTIE S, UNIVERSITY OF TEXAS, 5323 HARRY
HINES BLVD, DALLAS, TEX. Microsomal electron transport in liver and
heart (human, mammals).
R01HL-I3623-08 (CVB) GOETZ, KENNETH L, ST LUKE'S HOSPITAL, WORNALL
ROAD AT FOURTH STREET , KANSAS CITY, MO. Atrial receptors (dogs)
ROIHL-1 3626-06 (MET) WILSON, DANA E, UNIVERSITY OF UTAH. 50 NORTH MEDI-
CAL DRIVE, SALT LAKE CITY, UTAH. Lipoprotein lipase and lipoprotein
removal (human, rats, bacteria).
ROIHL-1 3629-08 (HEM) ASTER, RICHARD H, MILWAUKEE BLOOD CENTER INC
1701 WEST WISCONSIN AVENUE, MILWAUKEE, WIS. Hemorrhagic dis-
eases (human).
ROIHL-1 3630-08 (PC) THOMAS, JAMES A, IOWA STATE UNIVERSffY, DEPT OF
BIOCHEM & BIOPHYSICS. AMES. IOWA. Control of glycogen synthesis
in heart (cattle).
ROIHL-1 3632-08 (PTHA) JACKSON, ROBERT L, UNIVERSITY OF MISSOURI, DE-
PARTMENT OF PEDIATRICS. COLUMBIA, MO. Vascular changes in
diabetes mellitus (human).
ROIHL-1 3634-08 (CVB) BRINKMAN, CHARLES R, III, UNIVERSITY OF CALIFOR-
NIA, 405 HILGARD AVENUE, LOS ANGELES, CALIF. Renal hypertension
in pregnancy (sheep).
537
«01Ml-)36S6.oe (PHRA) BRfSSllR. IIU»IN, UNIVtRSlIV OF ARIZONA. COLLEGE
Of MEDICINE, TUCSON. ARI/ EH«cls ol plutnucolojic Jgenis on
heait metabolism (human, rodents)
H0IMI-U639.07 (CVA) WIUIAMS. JOHN f. J«, UNIVERSITY OF TEXAS. DEPART
MENT OF MEDICINE, GALVESTON. TEX Fjclois altering the course o(
myocardial dysfunction (cats)
R0tHl.13«45-U (CVA) CARLSON, JAMES R, WASHINGTON STATE UNIVERSITY.
OEPI OF ANIMAl SCIfNCES. PUllMAN. WASH Trvplophan induced pul-
monaiy emphysema (cattle, goats, labbits)
ROlHL.13651-07 (BMT) HAVES. ROBERT G, UNIVERSITY OF NOTRE DAME.
CHEMISTRY DEPARTMENT, NOTRE DAME, IND X ray photoelectron spec-
troscopy ol heme compounds
R0IHL-)36S2-08 (MCHB) HENORICKSON, DAVID N. UNIVERSITY Of ILLINOIS.
SCHOOL OF CHEMICAL SCIENCES. URBANA. ILL Metal sites in metal
loproteins (mushroom).
ROtHl-1 3654-08 (CVA) COFFMAN, JAY D. 7S EAST NEWTON STREET. BOSTON.
MASS Antilipemic regimes in peripheral arteriosclerosis (human)
ROlHl-l 3666-06 (PHRA) ROBERTS, JAY, MED COLLEGE OF PENNSYLVANIA. 3300
HENRY AVENUE, PHILADELPHIA. PA, Pharmacology ot genesis of car-
diac rhythmicity (rats, cats)
ROlHl-1 3694-08 (PTHA) WIUIAMSON, JOSEPH R, WASHINGTON UNIVERSITY.
OEPT OF PATHOLOGY. ST LOUIS. MO Capillary basement membrane in
cardiovascular disease (human, rats)
R01 HI- 137 15-08 (END) LEVEY, GERALD S, UNIVERSITY OF MIAMI. POST OFFICE
BOX 520875. MIAMI, FLA Myocardial adenyl cyclase (rats)
ROlHl-1 3722-08 (PTHA) KRITCHEVSKY, DAVID, UNIVERSITY OF PENNSYLVANIA.
3400 SPRUCE STREET. PHILADELPHIA. PA. Acid and alkaline lipases in
aortas (rats, rabbits, human)
POIHl-l 3737-07 (HEP) KANTROWIT2, ADRIAN, SINAI HOSPITAL OF DETROIT.
6767 WEST OUTER DRIVE. DETROIT. MICH. Assisted circulation.
POIHl-1 3737-07 0002 (HEP) FREED, PAUL S. Assisted circulation U-shaped
mechanical auxiliary ventricle (dogs).
POIHL-1 3737-07 0005 (HEP) WELKOWITZ, WAITER. Assisted circulation
Piezoelectric assist device (animals).
POlHL-1 3737-07 0006 (HEP) WELKOWITZ, WALTER. Assisted circulation Porta
ble driving unit for permanent assist devices (dogs).
POIHl-1 3737-07 0007 (HEP) MOSKOWITZ, MITCHELL S. Assisted circulation -
Determination of cardiac status by use of balloon pump (dogs).
POIHl-1 3737-07 0008 (HEP) FREED, PAUL S. Assisted circulation Phase shift
balloon pumping alternate designs.
POlHL-1 3737-07 0009 (HEP) WELKOWITZ, WAITER. Assisted circulation
Analytical models.
POlHl-13737-07 0013 (HEP) FREED, PAUL S. Assisted circulation-Incorporation
of sensors (human, dogs).
POlHl-13737-07 0024 (HEP) FREED, PAUL S. Assisted circulation Dynamic
prosthetic myocardium (dogs).
POlHl-13737-07 0025 (HEP) MOSKOWITZ, MITCHELL S. Assisted circulation
Driving system based on quantitative criteria (human, dogs).
P01HH3737-07 0026 (HEP) MAMMEN, EBERHARD F. Assisted circulation--
Hemostatic mechanism (human, dogs).
POlHl-1 3737-07 0027 (HEP) MOSKOWITZ, MITCHELL S. Assisted circulation-
Optimization of cardiac assistance (dogs).
POIHl-1 3737-07 0028 (HEP) KANTROWITZ, ADRIAN. Assisted circulation -
Clinical studies of intraaortic balloon pumping.
POlHl-1 3737-07 0029 (HEP) KANTROWITZ, ADRIAN. Assisted circulation -
Chronic left ventricular failure (human).
POIHl-1 3737-07 0030 (HEP) RUBENFIRE, MEIVYN. Assisted circulation Myocar-
dial ischemia -Effects of phase-shift balloon pumping (dogs).
P01HH 3737-07 0031 (HEP) WHITTY, ALBERT J. Assisted circulation Myocardial
ischemia-Biochemical changes (dogs).
POIHl-1 3737-07 0032 (HEP) KANTROWITZ, ADRIAN. Assisted circulation The
dynamic aortic patch (human, dogs).
POlHl-1 3737-07 0033 (HEP) SAWATANI, SATOSHI. Assisted circulation Au
tologous bioprosthetic grafts for coronary artery bypass surgery
(human, dogs).
POlHL-13737-07 0034 (HEP) MOSKOWITZ, MITCHELL S. Assisted circulation-
Phasic aortic flov» and cardiac output from phasic pressures (dogs).
POIHL- 13737-07 0035 (HEP) MOSKOWITZ, MITCHELL S. Assisted circulation-
Mapping the geometry and elasticity of the aorta.
POlHl-1 3737-07 0036 (HEP) MOSKOWITZ, MITCHELL S. Assisted circulation-
Assessment of infarct size from hemodynamic measurements.
POlHl-1 3737-07 0037 (HEP) HAMOUDA, FAROUK A. Assisted circulation-
Clinical measurement of blood flow through aorto-coronary vein
bypass graft.
POlHL-l 3737-07 0038 (HEP) HAMOUDA, FAROUK A. Assisted circulation-
Distinguishing the ischemic ventricle from scarred ventricle by balloon
pumping.
POlHL.13737-07 0039 (HEP) MOSKOWITZ, MITCHELL S. Assisted Circulation-
Computer controlled intraortic balloon pumping.
POIHl-l 3738-08 (HEP) KOLFF, WILLEM J, UNIVERSITY OF UTAH. BUILDING 518.
SALT LAKE CITY, UTAH. Cardiac assist devices and artificial hearts.
POlHL-1 3738-08 0001 (HEP) DONOVAN, FRANK. Cardiac assist devices and
artificial hearts-Cardiac assist devices (human, sheep).
POIHL-1 3738-08 0002 (HEP) KOLFF, WILLIAM J. Cardiac assist devices and ar
tificial hearts-Total replacement with artificial heart (calves, sheep,
ponies).
P01HL-13738-08 0003 (HEP) PETERS, JEFFREY I. Cardiac assist devices and ar
tificial hcarts-Pathophysiological effects of the artificial heart
(calves).
POIHL-13738-08 0004 (HEP) KWAN-GETT, CLIFFORD S. Cardiac assist devices
and artificial hearts-Hematological evaluation of prosthetic materials
(calves).
POlHL-13738-08 0005 (HEP) LYMAN, DONALD J. Cardiac assist devices and
artificial hearts-Development of new materials for artificial heart and
assist devices (sheep, dog).
R01HL-1 3754-08 (SGYB) SALZMAN, EDWIN W, BETH ISRAEL HOSPITAL. 330
BROOKLINE AVENUE, BOSTON. MASS, Postoperative thromboembolism
in surgical patients (human).
ROlHl-13803-07 (SGYB) CLARK, RICHARD E, 4960 AUDUBON AVENUE, ST LOUIS.
MO. Advanced cardiac valvular and vascular prosthesis (dogs,
baboons).
R01HL-1 3824-06 (CVA) lOURENCO, RUY V, 840 SOUTH WOOD STREET. POST OF
FICE BOX 6998. CHICAGO. ILL. Defense mechanisms in pathogenesis
of emphysema (human, dogs).
PROJECT NUMBER AND INVESTIGATOR ADDRESS
R01Hl.l3831-0e (MBY) MANASfK, FRANCIS J, UHIVFRSITY OF CHICAGO. 102b
EAST 57IH SIR! FT. CHICAGO, ILl factors re|ul<tin| embryonic car
diac moiphogenciis (chicK. salamandra)
R01 HI- 1 384 1-1 6 (AFY) MINES, ALLAN H, UNIVfRSITY Of CALIFORNIA. THIRD AND
PARNASSUS. SAN FRANCISCO. CAtIf Reipiralion during altitude accli
mali/alion (((oalv doC'., rats, rabbil'.)
P01HL.138S1-I6 (HEPA) TER-POGOSSIAN, MICHEL M, MALLINCKRODI INST OF
RADIOLOGY. 510 SOUTH KINGSHIGHWAY. ST LOUIS. MO Cyclotron
produced isotopes in biology and medicine (human, animals)
ROIHl.13870-09 (CVB) ENTMAN, MARK I, METHODIST HOSPITAL. 6516 BERTNER
BOULEVARD. HOUSTON. TEX Control of myocardial saccolubular calci-
um stores (dogs)
ROlHl-13881-08 (HEM) WICKERHAUSER, MILAN, AMERICAN NATIONAL RED
CROSS. 9312 OLD GEORGETOWN ROAD. BETHESOA. MD The American
Red Cross National Fractionation Center
ROIHL-l 3885-08 (SSS) MATTHEWS, lEROY W, CASE WESTERN RESERVE UNIV.
2103 ADELBERT ROAD. CLEVELAND. OHIO Cystic fibrosis and pulmo
nary disease
ROIHL-l 3885-08 0005 (SSS) WOOD, ROBERT E. Cystic fibrosis and pulmonary
disease Evaluation ol lobar pulmonary lavage (human),
ROIHl-1 3885-08 0006 (SSS) POU>*AR, STEPHEN H. Cystic fibrosis and pulmo
narv disease Cell mediated immunity and Pseudomonas infections in
cystic fibrosis (human)
ROIHl.13885-08 0007 (SSS) THOMASSEN, MARY JANE. Cystic fibrosis and
pulmonary disease Alveolar macrophage defense mechanism (human,
rabbits)
ROIHl-1 3885-08 0008 (SSS) DEARBORN, DORR G. Cystic fibrosis and pulmo
nary disease Pseudomonas specific activation of alveolar
macrophages (human, rabbits),
ROlHl-1 3885-08 0009 (SSS) BOAT, THOMAS F. Cystic fibrosis and pulmonary
disease -Respiratory mucus glycoproteins (human, rabbits)
R01HL-I3885-08 9001 (SSS) DOERSHUK, CARL F. Cystic fibrosis and pulmonary
disease-Pulmonary function core facility (infants, children).
ROIHL-l 3885-08 9002 (SSS) PRIMIANO, F P. Cystic fibrosis and pulmonary dis
ease-Computer core facility (human).
ROIHL-1 3885-08 9003 (SSS) WOOD, ROBERT E. Cystic fibrosis and pulmonary
disease-Fiberoptic bronchoscopy core facility (human, dogs, sheep).
ROlHl-1 3888-1 5 (CVA) SAL2ANO, JOHN V, DUKE UNIVERSITY. DEPT OF
PHYSIOLOGY & PHARM. DURHAM. N C. Regulation of respiration.
ROIHL-l 3901 -08 (PTHA) LEAK, LEE V, HOWARD UNIVERSITY. DEPARTMENT OF
ANATOMY. WASHINGTON. D C. Ontogeny, ultrastructure. function in
lymphatic system (birds, fish, mammals).
ROIHl-l 3909-27 (BBCA) CANN, JOHN R, UNIVERSITY OF COLORADO. 4200 EAST
NINTH AVENUE. DENVER. COLO. Physiocheraistry and immunology of
macromolecules. __„
ROIHL-l 39 1 7-20 (CVB) LUETSCHER, JOHN A, JR, STANFORD UNIVERSITY. 300
PASTEUR. STANFORD. CALIF. Secretion and effects of adrenal hor-
mones (human, rabbits, sheep).
ROIHL-l 3920-07 (SGYA) SEAIY, WILL C, DUKE UNIVERSITY. DURHAM. N C Ex-
panding the role of surgery of atrial dysrhythmias (dogs).
R0IHL-I392I.07 (CVA) HEINEMANN, HENRY O, CORNELL UNIVERSITY. 1300
YORK AVENUE. NEW YORK. N Y. The lung as a metabolic organ
(animals).
ROlHl-1 3929-06 (PHY) TANNER, GEORGE A, INDIANA UNIVERSITY. 1100 WEST
MICHIGAN STREET. INDIANAPOLIS. IND. Single nephron response to
chronic obstruction (frogs, rats).
ROlHl-1 3936-06 (CVB) HUTCHINS, PHILLIP M, WAKE FOREST UNIVERSITY. DE-
PARTMENT OF PHYSIOLOGY. WINSTON SALEM. N C. Microvascular
responses in hypertension (human, rats)
ROlHL-13974-07 (EDC) RUBERMAN, WILLIAM, HLTH INSURANCE PLAN. 625
MADISON AVENUE. NEW YORK. N Y. Ventricular premature beats and
sudden coronary death (human).
ROIHL-1 3987-04 (SGYA) BLUMENSTOCK, DAVID A, MARY IMOGENE BASSEH
HOSPITAL. ATWELL ROAD. COOPERSTOWN. N Y. Transplantation of the
lung (dogs).
ROlHL-1 3988-07 (SGYA) HUGHES, HOWARD C, PENNSYLVANIA STATE UNIVERSI
TY. COLLEGE OF MEDICINE. UNIVERSITY PARK. PA. Elimination of
reoperative cardiac pacemaker surgery (dogs).
ROlHL-l 3989-05 (BBCB) BRILL, ARTHUR S, UNIVERSITY OF VIRGINIA. OEPT OF
PHYSICS. CHARLOTTESVILLE. VA. Role of water in respiratiory protein
structure.
ROlHL-14020-06 (BBCB) STRACHER, ALFRED, S U N Y DOWNSTATE MED
CENTER. 450 CURKSON AVENUE. BROOKLYN. N Y. Characterization of
myosin from blood platelets (rabbit).
ROlHL-1 4092-07 (CVB) RENNICK, BARBARA R, S U N Y AT BUFFALO. 127
FARBER HALL. BUFFALO. N Y. Homeostatic regulation of plasma
choline (rats, dogs, chickens).
ROlHl-1 41 02-07 (AFY) HOUSTON, CHARLES S, UNIVERSIH OF VERMONT. DEPT
OF ENVIRONMENTAL HEALTH. BURLINGTON. VT. Human physiology at
5360 meters-Mountain environment.
ROlHl-141 11-07 (BBCB) ENGEUVtAN, DONALD M, YALE UNIVERSITY. BOX 1937
YALE STATION. NEW HAVEN. CONN. Cholesteryl esters in membranes
and atherosclerosis (human, swine).
ROlHL-14126-17 (SGYB) KRIPPAEHNE, WILLIAM W, UNIVERSITY OF OREGON.
3181 S W SAM JACKSON PARK RD. PORTUND. OREG. Effect of func-
tion on grafts and implants of collagen (dogs, monkeys).
ROIHl-14127-16 (TOX) SMITH, ROGER P, DARTMOUTH MEDICAL SCHOOL. DEPT
PHARMACOLOGY & TOXICOLOGY. HANOVER. N H. Methemoglobinemia
and antihypertensive drugs (cats. mice. rats).
R01HL-M131-18 (HEM) MC CURDY, PAUL R, AMERICAN RED CROSS. 2025 E
STREET, N W. WASHINGTON. D C, Abnormal hemoglobin syndromes
(human).
ROlHL-1 41 33-08 (GMB) KNOX, FRANKIYN G, MAYO FOUNDATION. 200 FIRST
STREET SOUTHWEST. ROCHESTER. MINN. Intrarenal regulation of sodi-
um reabsorption (dogs, hamsters, rats).
P50HI-1 41 36-07 (HIBA) BURROWS, BENJAMIN, ARIZONA MEDICAL CENTER.
1501 NORTH CAMPBELL AVENUE. TUCSON. ARIZ. Pulmonary SCOR-Air-
ways obstructive diseases.
P50HI-141 36-07 0001 (HIBA) KNUDSON, RONALD J. Pulmonary SCOR Air-
ways obstructive diseases-Experimental airway obstructive disease
(dogs).
P50HL-1 41 36-07 0003 (HIBA) FUIGINITI, VINCENT A. Pulmonary SCOR -Air
ways obstructive diseases-Acute pediatric respiratorv disease and
COLO.
PROJECT NUMBER AND INVESTIGATOR ADDRESS
538
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PSOHL
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ROIHL
14136-07 0004 (HIBA) BUTLER, COOLEY, II. Pulmonary SCOR-Aitways
obstructive diseasese-Morphometric studies of developing emphysema
(human).
14136-07 OOOS (HLBA) FREUNDLICH, IRWIN M. Pulmonary SCOR Air
ways obstructive diseases -Radiographic studies of airways obstructive
disease (human)
14136-07 0009 (HLBA) BURROWS, BENJAMIN. Pulmonary SCOR Air
ways obstructive diseases -Tuscon epidemiological study of airways
obstructive disease (human),
14136-07 0016 (HLBA) LEBOWITZ, MICHAEL D- Pulmonary SCOR Air
ways obstructive diseases -Environmental factors in airways obstruc-
tive diseases (human).
14136-07 0017 (HLBA) TAUSSIG, LYNN M. Pulmonary SCOR -Airways ob-
structive diseases-Pediatric airways obstructive disease (human)
14136-07 9001 (HLBA) LEBOWITZ, MICHAEL D. Pulmonary SCOR Air
ways obstructive diseases -Biometrics core.
14136-07 9002 (HLBA) KNUDSON, RONALD J. Pulmonary SCOR -Air
ways obstructive diseases -Physiology core (human, animal)
■14136-07 9003 (HLBA) BUTLER, COOLEY II. Pulmonary SCOR -Airways ob-
structive diseases-Pathology core (human, dogs).
14136-07 9004 (HLBA) NUDELMAN, SOL. Pulmonary SCOR -Airways ob
structive diseases-Radiology core (human).
14136-07 900S (HLBA) BARBEE, ROBERT. Pulmonary SCOR-Airways ob
structive diseases-Clinical core.
-14136-07 9006 (HLBA) TAUSSIG, LYNN M. Pulmonary SCOR Airways ob-
structive diseases-Pediatric lung function core.
■14136-07 9007 (HLBA) BURROWS, BENJAMIN. Pulmonary SCOR Air-
ways obstructive diseases -Special facilities core.
-14138-OS (SRC) BLANKENHORN, DAVID H, UNIV OF SOUTHERN CALIFOR-
NIA, 2025 ZONAL AVENUE, LOS ANGELES. CALIF. Center for research
on atherosclerosis
■ 14138-OS 0008 (SRC) CHIN, H P- Center for research on atherosclerosis-
Core lipid laboratory (human).
14138-OS 0009 (SRC) CRAWFORD, DONALD W. Center for research on
atherosclerosis-Core anglographlc-diagnostic laboratory (human dogs
birds).
14138-05 0010 (SRC) SELVESTER, RONALD H. Center for research on
atherosclerosis -Diet and exercise as therapy in men with premature
atherosclerosis.
14138-OS 0014 (SRC) BROOKS, SAMUEL H. Center for research on
atherosclerosis -Core blostatistlcs laboratory
-14I38.0S 001S (SRC) ZEMPLENYI, TIBOR K. Center for research on
atherosclerosis-Arterial wall-Intermediary metabolism, enzyme activity
and bloenergetics.
■14138-OS 0016 (SRC) SELZER, ROBERT. Center for research on atheros-
clerosis-Computer analysis of angiograms.
-MI4I-0S (SRC) JESSE, MARY J, UNIVERSITY OF MIAML P 0 BOX 875
BISCAYNE ANNEX, MIAMI, FLA. SCOR for atherosclerosis in childhood
■ 14141-05 0001 (SRC) JESSE, MARY JANE. SCOR for atherosclerosis in
childhood-Clinical Implications (Infants and children).
■ 14141-05 0002 (SRC) LITTLE, WIUIAM. SCOR for atherosclerosis in child-
hood-lntrauterine environment of proband group (human).
•14141-05 0003 (SRC) HSIA, S L SCOR for atherosclerosis In childhood-De-
tection of abnormalities in lipid metabolism (human, rabbits rats)
14141-05 0007 (SRC) CLEVELAND, WILLIAM W. SCOR for atherosclero-
sis in childhood -Relation of lipid valves to sexual maturation at pu-
berty (human).
14141-05 0008 (SRC) HSIA, S L SCOR for atherosclerosis in childhood-
Core laboratory.
14147-08 (SRC) MAJERUS, PHILIP W, WASHINGTON UNIVERSITY, 660 S
EUCLID. ST LOUIS, MO. Specialized center of research in thrombosis
14147-08 0001 (SRC) MAJERUS, PHILIP W. Tpecialized center of
research in thrombosis-Role of aspirin, other anti-platelet agents In
platelet function (rat, human).
14147-08 0003 (SRC) JACKSON, CRAIG M. Specialized center of
research In thrombosis-Surface thrombogenlclty and phospholipid
vesicle physical properties.
14147-08 0006 (SRC) SHERMAN, LAURENCE A. Specialized center of
research in thrombosis-Clearance mechanisms of coagulation moie-
ties (human, rabbits, rodents).
14147-08 0007 (SRC) WELCH, MICHAEL J. Specialized center of research
in thrombosis-Radioactive tracers in recognition of intravascular
coagulation (human, dogs).
14147-08 0012 (SRC) BAENZIGER, NANCY L. Specialized center of
research in thrombosis-Tissue culture study of arterial cells (human
hamster).
-14147-08 0013 (SRC) ELLIOT, DAVID L Specialized center of research in
thrombosis-Mathematical models of blood coagulation kinetics
14147-08 0014 (SRC) ABRAHAM-SHRAUNER, BARBARA. Specialized
center of research In thrombosis-Theoretical models for electrostatic
effects in blood clot formation.
14147-08 0015 (SRC) PiCKARD, WILLIAM f. Specialized center of
research In thrombosis-Charge related properties of phospholipid sur-
faces In monolayers and vesicles.
14147-08 0016 (SRC) SIEGEL, BARRY A. Specialized center of research In
thrombosis-Nuclear medicine core laboratory (human, dogs rats rab-
bits).
■ 14147-08 0017 (SRC) JOIST, JOHANN H. Specialized center of research
in thrombosis -Core coagulation laboratory (human).
■14147-08 0018 (SRC) DEUEL, THOMAS F. Specialized center of research
in thrombosis -Biochemical aspects of platelet function In thrombosis
and cell growth (human).
■14148-07 (RAD) CANNON, PAUL J, COLUMBIA UNIVERSITY, 630 W/EST
168TH STREET, NEW YORK, N Y. The regional circulations.
■14148-07 0002 (RAD) LEVITT, MORTON. The regional circulations-
Catecholamine metabolism In subtypes of hypertension (human,
animals).
14148-07 0004 (RAD) SPALTER, HAROLD F. The regional circulatlons-
Funduscopic mapping by photography (human),
14148-07 0007 (RAD) WOTMAN, STEPHEN. The regional circulations-
Salivary composition In hypertension (human).
14148-07 0008 (RAD) CANNON, PAUL J. The regional circulations-
Renal circulation In hypertensive patients (also dogs)
14148-07 0009 (RAD) CANNON, PAUL J. The regional circulations-
Myocardial circulation in hypertension and atherosclerosis (human).
PS0HL-141S3
PSOHL-14153
P50HL-14153-
PS0HL-141S3
PS0HL-I4IS3
P50HL-14153-i
PS0HL-I41S3
PSOHL
PSOHL
PSOHL
PSOHL
PSOHL
PSOHL-
14153
■14153
14153
14153
14153
14159.
PS0HL-141S9
PSOHL-14159-
PS0HL-I41S9
P50HL-14159
PSOHL-1 41 53-07 (SRC) MENKES, HAROLD A, JOHNS HOPKINS UNIVERSITY JOHNS
HOPKINS LUNG CENTER-CHR, BALTIMORE, MD. Johns Hopkins Lung
Center-Chronic diseases of airways.
■07 0001 (SRC) COHEN, BERNICE H. Johns Hopkins Lung Center-
Chronic diseases of airways -Genetic and environmental factors in
chronic pulmonary disease (human).
07 0004 (SRC) DANNENBERG, ARTHUR M. Johns Hopkins Lung
Center-Chronic diseases of alrways-Macrophage enzymes In lung Inju-
ry, Inflammation and repair (rabbit).
■07 0010 (SRC) TOCKMAN, MELVYN S. Johns Hopkins Lung
Center-Chronic diseases of airways-Risk factors for airways obstruc-
tion in a rural community (human).
-07 0011 (SRC) NORMAN, PHILIP S. Johns Hopkins Lung Center-
Chronic diseases of airways-Allergy, airways reactivity and asthma In
human ragweed allergy.
■07 0012 (SRC) ADKINSON. N FRANKLIN. Johns Hopkins Lung
Center-Chronic diseases of airways -Aspirin Intolerance in reversible
lung disease (human).
•07 0013 (SRC) ADAMS, G KENNETH. Johns Hopkins Lung Center-
Chronic diseases of airways-Pulmonary mechanics and mediators of
allergic reactions (guinea pigs, human).
07 0014 (SRC) LICHTENSTEIN. LAWRENCE M. Johns Hopkins
Lung Center-Chronic diseases of airways-Mediator release in asthma
(human).
-07 0015 (SRC) NEWBALL, HAROLD H. Johns Hopkins Lung
Center-Chronic diseases of airways -KInins and human lung.
-07 0016 (SRC) PROCTOR, DONALD F. Johns Hopkins Lung Center-
Chronic diseases of airways-Airways defense mechanisms (dogs)
-07 0017 (SRC) TRAYSTMAN, RICHARD J. Johns Hopkins Lung
Center-Chronic diseases of airways-Collateral ventilation and pulmo-
nary interdependence (pig, dog, human).
-07 0018 (SRC) PERMUTT, SOLBERT. Johns Hopkins Lung Center-
Chronic diseases of airways -Pulmonary function core.
■07 0019 (SRC) HUTCHINS, GROVER M. Johns Hopkins Lung
Center-Chronic diseases of airways-Pathology core (human, animal).
■08 (SRC) WEINBERGER, MYRON H, INDIANA UNIVERSITY 1100
WEST MICHIGAN STREET, INDIANAPOLIS. IND. Specialized center of
research in hypertension.
■08 0008 (SRC) WILLIS, LYNN R. Specialized center of research in
hypertension-Renal function and sodium metabolism In hypertension
(rats, human, rabbits).
■08 0018 (SRC) WATANABE, AUGUST M. Specialized center of
research in hypertension-Sympathetic nervous system in hypertension
(rats).
■08 0020 (SRC) WEINBERGER, MYRON H. Specialized center of
research In hypertenslon-Renln-mineralocorticoid system In hyperten-
sion (human, rat, dog).
■08 0021 (SRC) GRIM, CLARENCE E. Specialized center of research
in hypertension-Genetic studies of the physiology of hypertension
(human, rats).
-08 0022 (SRC) WEINBERGER, MYRON H. Specialized center of
research in hypertension-Core laboratory.
-08 0023 (SRC) GRIM. CLARENCE E. Specialized center of research
in hypertension-Core computation.
-08 0024 (SRC) GRIM. CLARENCE E. Specialized center of research
in hypertension -Core resources (clinical, animal models).
■07 (HLBA) CLARKSON, THOMAS B, WAKE FOREST UNIVERSITY
BOWMAN GRAY SCHOOL OF MED, WINSTON-SALEM, N C. A/S SCOR-^
Comparative and experimental atherosclerosis.
■07 0025 (HLBA) LEHNER, NOEL D M. A/S SCOR -Comparative and
experimental atherosclerosis -Animal care resource and laboratory
animal medicine unit (monkeys, pigeons).
■07 0026 (HLBA) BULLOCK, BlU C. A/S SCOR Comparative and ex-
perimental atherosclerosis-Comparative pathology unit (pigeons mon-
keys).
-07 0027 (HLBA) CLARKSON, THOMAS B. A/S SCOR-Comparatlve
and experimental atherosclerosis-Hyper- and hyporesponslveness to
dietary cholesterol (squirrel monkey).
-07 0028 (HLBA) CLARKSON, THOMAS B. A/S SCOR-Comparative
and experimental atherosclerosis-Hyper- and hyporesponslveness to
dietary cholesterol (African green monkey).
■07 0029 (HLBA) WAGNER. WILLIAM D. A/S SCOR -Comparative
and experimental atherosclerosis-Development of pigeon substrains
■07 0030 (HLBA) TRILLO. ALBERTO. A/S SCOR-Comparatlve and ex-
perimental atherosclerosis-Morphology, angiochemlstry-Oiet Induced
lesions in African green monkey.
■07 0031 (HLBA) BOND, M GENE. A/S SCOR-Comparative and ex-
perimental atherosclerosis-Changes in endothelial permeability as-
sociated with atherosclerosis (pigeon).
07 0032 (HLBA) CLARKSON, THOMAS B. A/S SCOR-Comparative
and experimental atherosclerosis-Plasma cholesterol, lesion regression
and vascular function (Rhesus monkey).
07 0033 (HLBA) RUDEL, LAWRENCE L. A/S SCOR-Comparatlve
and experimental atherosclerosis-Comparative studies of lipoprotein
distribution and metabolism (monkeys).
07 0034 (HLBA) STCLAIR, RICHARD W. A/S SCOR-Comparative
and experimental atherosclerosis-Core lipid analytic laboratory
07 0035 (HLBA) STCLAIR, RICHARD W. A/S SCOR Comparative
and experimental atherosclerosis-Llpid metabolism-Interaction with
arterial metabolism (monkey, pigeon).
07 0036 (HLBA) STCLAIR, RICHARD W. A/S SCOR-Comparative
and experimental atherosclerosis-Connective tissue metabolism-In-
teraction with arterial metabolism (monkeys).
-07 0037 (HLBA) STCLAIR, RICHARD W. A/S SCOR-Comparative
and experimental atherosclerosis-Genetic control of plasma
cholesterol-Interaction of dietary fatty acid (monkey).
-07 0038 (HLBA) GREEN, HAROLD D. A/S SCOR-Comparatlve and
experimental atherosclerosis-Peripheral vascular studies-Cholesterol,
lesion regression, vascular function.
■07 0039 (HLBA) RHYNE, A LEONARD. A/S SCOR-Comparative
and experimental atherosclerosis-Statistical resource and research
management unit.
■07 0040 (HLBA) WAGNER, WILLIAM D. A/S SCOR-Comparative
and experimental atherosclerosis-Core anglochemistry laboratory.
PSOHL
PSOHL
PSOHL
PSOHL
■14159
14159
14159
14164
PSOHL-1 41 64
P50HI-14164
P50HL-I4164
PSOHL-14164
PSOHL
PSOHL
14164
14164
PSOHL-14164
PSOHL-14164
PSOHL-1 4164-
PSOHL
P50HL-
14164
14164
P50HL-14I64-
P50HL-14164
PSOHL-14164
P50HL-14164
PSOHL-14164-
339
PSOHl-14164-07 0041 (HltA) CLARKSON, THOMAS B. A/S SCOR Compirillva
and tipenmenUI atheroscleiosis Nonhuman primata padiatdc
atheroscleiosis risk lactot
PSOHl-l 41 64-07 0043 (HLBA) IfHNIR, NOEl O M. A/S SCOR Compatative and
aiperimental atherosclerosis Comparative cardiology laboratory
(monkeys)
PSOHL-14164-07 0043 (HIBA) lEWIS, JON C. A/S SCOR Comparative and ex
penmental atherosclerosis flection microscopy resource laboratory
PSOHl-14164-07 0044 (HIBA) UWIS, JON C. A/S SCOR Comparative and ex
penmental atherosclerosis Cell biology atherosclerosis proiect
(pigeons)
P50HI-141 87-07 (SRC) SAID, SAMI I, UNIVERSITY OF TEXAS. 4500 S UNCASTER
ROAD, DALLAS. TEX Pulmonary SCOR Chemical mediators in pulmo
nary vascular responses
P50HH41 87-07 OOOS (SRC) MUlllNS, CHARLES B. Pulmonary SCOR Chemical
mediators in pulmonary vascular responses Pulmonary hypertension
and cardiac function (dogs, human)
P50HI-141 87-07 0008 (SRC) WILSON. JAMES E, III. Pulmonary SCOR Chemical
mediators in pulmonary vascular responses Pulmonary thromboembol
ism (dogs, human)
PSOHL-1 41 87-07 0012 (SRC) SAID, SAMI I. Pulmonary SCOR- Chemical mediators
in pulmonary vascular responses-Vasoactive mediators in pulmonary
disease (human, animal)
PS0Hl-1418"'-07 0014 (SRC) ERDOS, ERVIN G. Pulmonary SCOR Chemical
mediators in pulmonary vascular responses Metabolism and actions
of vasoactive peptides in lung (human, mammals)
PSOHl-l 41 87-07 0015 (SRC) JOHNSON, ROBERT I. Pulmonary SCOR-Chemical
mediators in pulmonary vascular responses- Pathophysiologic respon
ses of pulmonary capillary bed (dog. human).
PSOHl-1 41 87-07 0016 (SRC) REYNOLDS, ROILAND C. Pulmonary SCOR-Chemi-
cal mediators in pulmonary vascular responses -Core pathology service
(dogs, rabbits, human)
P50HH4192-08 (SRC) ALEXANDER, OATES J, VANDERBILT UNIVERSITY. DEPT
OF PHARMACOLOGY. NASHVILLE, TENN. Specialized center of research
in hypertension.
PSOHl-l 41 92-08 0001 (SRC) SHANO, DAVID G. Specialized center of research
in hypertension-Surgical and medical treatment of renovascular
hypertension (human).
P50HI-14I92-08 0002 (SRC) DEAN, RICHARD H. Specialized center of research
in hypertension-Hypertensive patients v»ith renal artery stenosis.
PSOHl-14192-08 0003 (SRC) FROIICH, JURGEN C. Specialized center of
research in hypertension -Prostaglandins as mediators of renin secre-
tion (human, dog).
PSOHl-14192-08 0004 (SRC) INAGAMI, TADASHI. Specialized center of
research in hypertension -Isolation and characterization of pure renin
(swine, rats, human, rabbits).
PSOHl-14192-08 0005 (SRC) HOlllFIELD, JOHN W. Specialized center of
research in hypertension-New techniques for recognition of renovascu-
lar hypertension (human, dogs).
P50HI-14192-08 0007 (SRC) SLATON, PAUL E. Specialized center of research in
hypertension-Role of new mineralocorticoids in hypertension (human,
rats).
P50HI-14192-08 0008 (SRC) BRILL, A B. Specialized center of research in hyper-
tension-New radiographic methods-Recognition of renovascular hyper-
tension (human, dog).
P50HL-14197-07 (SRC) STEINBERG, DANIEL, UNIV OF CALIFORNIA. SAN DIEGO.
DEPARTMENT OF MED. M013. LA JOLLA, CALIF. Support for center of
research on arteriosclerosis.
PSOHl-14197-07 0005 (SRC) STEINBERG, DANIEL. Support for center of
research on arteriosclerosis-Lipoprotein biosynthesis and degradation
in vivo and in vitro (human, animal).
P50HI-14197-07 0006 (SRC) GRUNDY, SCOTT M. Support for center of research
on arteriosclerosis-Diets and drugs affecting lipid metabolism
(human).
PS0HH4197-07 0007 (SRC) GRUNDY, SCOTT M. Support for center of research
on arteriosclerosis-Metabolic defects in familial hyperlipoproteinemias
(human).
P50HI-1 4 197-07 0008 (SRC) WEINSTEIN, DAVID B. Support for center of
research on arteriosclerosis -Core facility-Lipoprotein preparation, im-
munochemistiy.
P50HI-14212-07 (SRC) LOW, ROBERT B, UNIVERSITY OF VERMONT, DEPARTMENT
OF PHYSIOLOGY. BURLINGTON. VT. Correlated studies of pulmonary
fibrosis.
PSOHl-l 42 12-07 0001 (SRC) GRAHAM, WILLIAM G. Correlated studies of pul-
monary fibrosis -Clinical studies core.
P50HL-I4212-07 0004 (SRC) KELLEHER, PHILIP C. Correlated studies of pulmo-
nary fibrosis-Collagen metabolism in lung tissue and lung cells
(human, animal).
P50HI-14212-07 0006 (SRC) DAVIS, GERALD S. Correlated studies of pulmonary
fibrosis-Alvcolar macrophage physiology (human, rodents, rabbits).
P50HH4212-07 0007 (SRC) LOW, ROBERT B. Correlated studies of pulmonary
fibrosis-Protein metabolism in alveolar macrophages (rabbits, guinea
pigs, human).
P50HL-1 42 12-07 0011 (SRC) CRAIGHEAD, JOHN E. Correlated studies of pul
monary fibrosis-Pathology core (human, animal).
PSOHL-14212-07 0012 (SRC) CRAIGHEAD, JOHN E. Correlated studies of pul
monary fibrosis-lnorganic particulates in tobacco, smoke and lungs of
cigarette smokers (human).
P50HI- 142 12-07 0013 (SRC) HART, BETH A. Correlated studies of pulmonary
fibrosis-Mechanism of beryllium pathogenicity in the lung (human,
rabbit, guinea pig).
PSOHl-l 42 1 2-07 0014 (SRC) DAVIS, GERALD S. Correlated studies of pulmonary
fibrosis-Pulmonary lavage cells, secretions in diffuse intersititial lung
disease (human).
P50HI-14212-07 0015 (SRC) HEMENWAY, DAVID. Correlated studies of pulmo-
nary fibrosis-Pulmonary defense mechanisms and fibrotic lung dis-
ease (rodents, rabbits).
PSOHU14212-07 0016 (SRC) ABSHER, P MARLENE. Correlated studies of pul
monary fibrosis-Role of pulmonary alveolar macrophages in fibrosis
(human, rabbit).
P50HL-14212-07 0017 (SRC) SYLWESTER, DAVID I. Correlated studies of pulmo-
nary fibrosis-Biometry core.
PSOHl-l 42 14-07 (SRC) STAHIMAN, MILDRED T, VANDERBILT UNIVERSITY. DE-
PARTMENT OF PEDIATRICS. NASHVILLE. TENN. Newborn lung center for
hyaline membrane disease.
PROJECT NUMBER AND INVESTIGATOR ADDRESS
PSOHl-l 42 14-07 0012 (SRC) SNIll, JAMiS O. Newborn lung center (or hyaline
membrane disease Pulmonary stilus of children who had HMO at in
lants
PSOHl- 142 14-07 0013 (SRC) BUCHANAN, OiNTON C. Newborn lung canlei
for hyaline membrane disease Developmental outcome of children
who had HMD as infants
P50HI-14214-07 0015 (SRC) MENO, H C. Newborn lung center tor hyaline mem
brane disease Hormone effect on cyclic nucleotide lipid lyntheui in
developing lung (animal)
PSOHl-l 42 14-07 0020 (SRC) ORTH, DAVID N. Newborn lung center for hyaline
membrane disease Epidermal growth (actor effect Lung differentia
tion. maturation (human, rabbit)
PSOHl-l 43 14-07 0021 (SRC) lEQUIRE. VIRGIL S. Newborn lung center for
hyaline membrane disease Development of surfactant system Surfac
tant production and release (rat. rabbit)
PSOHl-14214-07 0022 (SRC) GRAY, MARY E. Newborn lung center for hyaline
membrane disease Functional integrity of surfactant system Hyaline
membrane disease (lamb, rat)
PSOHL-14214-07 0023 (SRC) CHYTIl, FRANK. Newborn lung center (or hyaline
membrane disease Regulation of fetal lung maturation Vitamin A
(rat. rabbit, sheep, human)
PSOHl-14214-07 0024 (SRC) ORTH, DAVID N. Newborn lung center for hyaline
membrane disease Synthesis and receptors tor ACTH in fetal lung
(human)
P50HI-1 42 14-07 0025 (SRC) BRIGHAM, KENNETH I. Newborn lung center (or
hyaline membrane disease Pulmonary vascular permeability and lung
water-Hyaline membrane disease (sheep)
PSOHl- 142 14-07 0026 (SRC) SUNDEll, HAKAN. Newborn lung center for hyaline
membrane disease-Hemodynamic studies of HMD-Prostaglandins
production and blockers (lambs)
PSOHl-14214-07 0027 (SRC) STAHIMAN, MILDRED T. Newborn lung center for
hyaline membrane disease -Oral-laryngeal chemoreceptors and respira-
tory failure in newborns (human, sheep).
PSOHl-l 42 14-07 0028 (SRC) GREEN, HARRY I. Newborn lung center for hyaline
membrane disease -Relationship of trace metals to respiratory failure
(dog. sheep, human).
PSOHl-1 42 14-07 0029 (SRC) SUNDEll, HAKAN. Newborn lung center for hyaline
membrane disease-The diving reflex-Perinatal asphyxia, pulmonary
ischemia and HMD (sheep)
P50HL-14214-07 0030 (SRC) COTTON, ROBERT B. Newborn lung center for
hyaline membrane disease-Effects of ductal patency-Impedance car-
diography and echocardiography (human).
P50HI-1 42 14-07 0031 (SRC) lAMBERTH, EDWIN I. Newborn lung center for
hyaline membrane disease-Essential fatty acid deficiency and HMD
(human).
PSOHL-14214-07 0032 (SRC) STAHLMAN, MILDRED T. Newborn lung center for
hyaline membrane disease-Evoked electroencephalographic potential
in infants with HMD (human).
PSOHl-l 42 14-07 0033 (SRC) COTTON, ROBERT B. Newborn lung center for
hyaline membrane disease-Statistical modeling, predictive classifica-
tion in clinical management of HMD.
PSOHL-14214-07 0034 (SRC) STAHLMAN, MILDRED T. Newborn lung center for
hyaline membrane disease-Core-Newborn intensive care unit.
P50HL-1 42 14-07 0035 (SRC) SUNDELL, HAKAN. Newborn lung center for hyaline
membrane disease-Core-Animal care facility.
P50HL-1 42 14-07 0036 (SRC) COTTON, ROBERT B. Newborn lung center for
hyaline membrane disease-Core-Biomedical engineering.
P50HI-1 42 14-07 0037 (SRC) lEQUIRE, VIRGIL S. Newborn lung center for
hyaline membrane disease-Core-Histopathology laboratories.
PSOHl-1 42 17-08 (SRC) SHERRY, SOL, TEMPLE UNIVERSITY. 3400 N BROAD
STREET. PHILADELPHIA. PA. Specialized center of research in thrombo-
sis.
P50HL-1 42 17-08 0048 (SRC) BUDZYNSKI, ANDREI Z. Specialized center of
research in thrombosis-Fibrinolysis section-Structural studies (human,
animal).
PSOHl-l 42 17-08 0049 (SRC) MARDER, VICTOR J. Specialized center of research
in thrombosis-Fibrinolysis section-Clinical studies.
PSOHl-l 42 17-08 0050 (SRC) STEWART, GWENDOLYN J. Specialized center of
research in thrombosis-Electron microscopy section (dogs).
PSOHl-l 42 17-08 0051 (SRC) WIEDEMAN, MARY P. Specialized center of
research in thrombosis-Microcirculation section (bat. hamster).
PSOHl-1 42 17-08 0052 (SRC) MALMUD, LEON S. Specialized center of research
in thrombosis-Radioisotope nuclear medicine section (human, dog),
PSOHl-1 42 17-08 0054 (SRC) NIEWIAROWSKI, STEFAN. Specialized center of
research in thrombosis-Coagulation section-Platelet aggregation
(human, pig. rabbit, dog).
PSOHL-1 42 17-08 0055 (SRC) WALSH, PETER N. Specialized center of research in
thrombosis-Coagulation section-Platelet coagulant activity (human).
P50HL-1 42 17-08 0057 (SRC) SAIGANICOFF, lEON. Specialized center of
research in thrombosis-Pharmacology-Platelet biochemistry (human,
animal).
PSOHl-l 42 17-08 0058 (SRC) MILLS, DAVID C B. Specialized center of research
in thrombosis-Mechanisms of induction and inhibition of platelet
reaction (human, pig).
P50HL-1 42 17-08 0059 (SRC) HOIMSEN, HOIM. Specialized center of research
in thrombosis-Energy metabolism and platelet function (human).
P50HI-1 42 17-08 0061 (SRC) HARAKAL, CONCETTA. Specialized center of
research in thrombosis-Pharmacology-Comparison of platelets and
vascular smooth muscle (animal).
PSOHL-l 42 17-08 0062 (SRC) KIRBY, EDWARD P. Specialized center of research
in thrombosis -Coagulation section-Factor VIII and Factor XII (human,
cattle).
PSOHl-l 42 17-08 0063 (SRC) WAISH, PETER N. Specialized center of research in
thrombosis-Special clinical studies laboratory.
PSOHl-l 42 18-07 (HIBA) JAMES, I STANLEY, COLL OF PHYSICIANS & SURG. 630
WEST 168TH STREET. NEW YORK, N Y. Pulmonary SCOR-Newborn lung
center.
P50HL-142 18-07 0004 (HIBA) WINTERS, ROBERT W. Pulmonary SCOR-Newborn
lung center-Metabolism of infants with respiratory distress syndrome
(human).
PSOHl-1 42 18-07 OOOS (HIBA) SPRUNT, KATHARINE. Pulmonary SCOR-Newborn
lung center -Prevention of infection in infants with respiratory distress
(human).
PROJECT NUMBER AND INVESTIGATOR ADDRESS
PS0HH42I8.07 0006 (HIBA) MANDl, INES. Pulmonary SCOR-Newborn lung
center-Biochemical characteristics of the lung in RDS (human
sheep).
P50HI-14218-07 0011 (HIBA) JAMES, I STANIEY. Pulmonary SCOR-Newborn
lung center-Admmistrative and computer core
PSOHl.14218-07 0012 (HIBA) JAMES, I STANIEY. Pulmonary SCOR-Newborn
lung center -Longitudinal study of RDS-On-line fetal and neonatal
monitoring (human).
P50HI-142I8-07 0013 (HIBA) INDYK, LEONARD. Pulmonary SCOR-Newborn
lung center-Longitudinal study of ROS-Monitoring fetal P02 and PC02
during labor (human).
P50H1.142I8-07 0014 (HIBA) YEH, MING-NENG. Pulmonary SCOR-Newborn
lung center-Longitudinal study of RDS-Monitoring fetal breathing
movements (human)
P50HL.14218.07 0015 (HIBA) DRISCOU, JOHN M, JR. Pulmonary SCOR-New-
born lung center-Long term follow-up of infants surviving RDS-Neu-
rological outcome (human)
P50HH42I8.07 0017 (HIBA) MELIINS, ROBERT B. Pulmonary SCOR-Newborn
lung center-Transvascular fluid exchange, vasoactive mediators in
RDS (sheep, cat).
PSOHl- 142 18-07 0018 (HIBA) DEU, RALPH B. Pulmonary SCOR-Newborn lung
center-Whole body buffering in acute hypercapnia (dogs)
PSOHL-1 4230-07 (SRC) SPECTOR, ARTHUR A, UNIVERSITY OF IOWA 4-550 BASIC
SCIENCES BLOC, IOWA CITY, IOWA. A/S SCOR-Lipids. atherosclerosis
and thrombosis.
PSOHL- 1 4230-07 0088 (SRC) LAUER, RONALD M. A/S SCOR-Lipids, atheros-
clerosis and thrombosis-Coronary risk factors in school children-The
Muscatine study.
PSOHL- 14230-07 0092 (SRC) SPECTOR, ARTHUR A. A/S SCOR-Lipids. atheros-
"^'^ ^"'' """"'I'osis -Tissue lipids-Cell culture studies (human)
PSOHL- 14230-07 0093 (SRC) BURNS, CHARLES P. A/S SCOR-Lipids. atheros
clerosis and thrombosis -Clinical studies involving cellular lipid con-
tent (human).
P50HH4230-07 0094 (SRC) ARMSTRONG, MARK I. A/S SCOR-Lipids. atheros-
clerosis and thrombosis-Studies of atherosclerosis and regression
(monkeys).
PSOHL-1 4230-07 0095 (SRO HOAK, JOHN C. A/S SCOR-Lipids, atherosclerosis
and thrombosis-Blood platelet adherence to endothelial smooth
muscle cells, fibroblast (human)
PSOHL- 1 4230-07 0096 (SRC) HOAK, JOHN C. A/S SCOR-Lipids, atherosclerosis
thrombosis-Ultrastructural studies of endothelial cells (human)
PSOHL- 14230-07 0097 (SRC) HOAK, JOHN C. A/S SCOR-Lipids, atherosclerosis
Dcnu. ,,.,,„ thrombosis-Studies of circulating platelet aggregates (human).
PSOHL- 14230-07 0098 (SRC) PENICK, GEORGE D. A/S SCOR-Lipids, atheros-
clerosis and thrombosis-Molecular properties of factor VIII (cattle
human, mice).
PSOHL- 1 4230-07 0099 (SRC) PENICK. GEORGE D. A/S SCOR-Lipids, atheros-
clerosis and thrombosis-Morphological, cytochemical study of normal
and altered vasculature (mice)
PSOHL-14230-07 9001 (SRC) WIEBE, DONALD A. A/S SCOR-Lipids, atherosclero-
sis and thrombosis-Core lipid laboratory
PSOHL- 14230-07 9002 (SRC) DEBAULT, LAWRENCE E. A/S SCOR-Lipids
»c«^ atherosclerosis and thrombosis-Core tissue culture laboratory
P50HL-14236-0S (SRC) AHRENS, EDWARD H, JR, ROCKEFELLER UNIVERSITY
66TH STREET AND YORK AVENUE, NEW YORK, N Y. Prevention of pre-
mature arteriosclerosis.
P50HI-14236-0S 0001 (SRC) GOODMAN, DEWITT S. Prevention of premature
arteriosclerosis-Metabolism and transport of cholesterol and vitamin
A (human, rats),
P50HL.14236-05 0002 (SRC) CANNON, PAUL J. Prevention of premature ar
teriosclerosis-Myocardial blood flow in patients with coronary
artherosclerosis.
PSOHl. 14236-05 0003 (SRC) NOSSEL, HYM.E L. Prevention of premature ar-
Piinu. ,,.,,x „ '"'"sclerosis -Intravascular clotting in patients with hyperlipidemia.
P50HL-14236.05 0004 (SRC) EDER, HOWARD A. Prevention of premature ar-
teriosclerosis-Plasma lipoproteins (human, rats)
PSOHL- 14236-05 0005 (SRC) DEMING. QUENTIN B. Prevention of premature ar
tenosclerosis-Genetically hyperlipidemic and hypolipidemic rats
PS0HH4236-0S 0006 (SRC) EDER, HOWARD A. Prevention of premature ar-
eriosclerosis-Carbohydrate metabolism and hypertriglyceridemia
(numan).
P50HL-14236-05 0007 (SRC) FRANK, CHARLES. Prevention of premature ar-
p^nu. ,..„. teriosclerosis-Exercise stress testing hyperlipoproteinemia (human).
PSOHL- 14236-05 0008 (SRC) BlUMENFELD, OIGA. Prevention of premature ar-
teriosclerosis-Lipoproteins of cell membranes (human)
PSOHL- 1 4236-05 0009 (SRC) AHRENS, EDWARD H, JR. Prevention of prema-
ure arteriosclerosis-Clinical studies on cholesterol metabolism
(human).
PSOHL- 1 4236-05 0010 (SRC) CORNFIELD, JEROME. Prevention of premature ar-
teriosclerosis-Computer programs.
PSOHL- 14236-05 0011 (SRC) SAMUEL, P. Prevention of premature arteriosclerosis-
Nutritional program.
PSOHL- 1 4236-05 0012 (SRC) INSULI, w. Prevention of premature arteriosclerosis-
Automated lipid analysis
PSOHL- 1 4236-05 0013 (SRC) HYMAN, MARTIN D. Prevention of premature ar-
teriosclerosis-Patient compliance,
PSOHL- 1 4237-07 (SRC) HAVEL, RICHARD J, UNIVERSITY OF CALIFORNIA 1315-
MOFFITT HOSPITAL. SAN FRANCISCO. CALIF. Support for arteriosclerosis
center,
PSOHl- 14237-07 0001 (SRC) HAVEL, RICHARD J. Support for arteriosclerosis
center-Role of apolipoprotems in lipoprotein catabolism (human
rats).
PSOHl- 1 4237-07 0002 (SRC) FIELDING, CHRISTOPHER J. Support for arterios-
clerosis center-Interactions of lipoprotein particles with vascular sur-
face (human, rat).
PSOHL-1 4237-07 0003 (SRC) KANE, JOHN P. Support for arteriosclerosis center -
'"'* "' ''PoP'o'eins and apolipoproteins (human, rabbits)
PSOHL.14237-07 0004 (SRC) HAMILTON, ROBERT L. Support for arteriosclerosis
center-Synthesis, secretion of normal, abnormal plasma lipoproteins
(rodents, monkeys).
P50HL-I4237.07 0005 (SRC) HAVEL, RICHARD J. Support for arteriosclerosis
center-Genetic determinants of apolipoprotein variability in
lipoproteins (human).
P50HL.I4237-07 0006 (SRC) KANE, JOHN P. Support for arteriosclerosis center-
Drug treatment of familial hyperbetalipoproteinemia (human).
540
PSOHl
ROIHl
ROIHl
ROIHt
R01HL-
ROIHL
ROIHL
POIHl
P01HL
POIHL
P01HL-
POIHl-
POIHl-
POIHl
POIHl
POIHL.
POIHL-
POIHL-
POIHL-
POIHL
POIHl
P01HL-
POIHl-
POIHl-
POIHL
POIHL.
POIHL-
POIHL-
POIHl
POIHL.
P01HL-
POIHL
POIHL-
P01HL-
POIHl
POIHl-
14237-07 0007 (SRC) HAVEL, RICHARD J. Support for arteriosclerosis
center-Core laboratories.
14262-07 (PTHA) JANOFF, AARON, SUNY AT STONY BROOK, SCH OF
BASIC HEALTH SCIENCES, STONY BROOK, N Y. Leukocyte proteases
and their lung targets (human, dogs, rabbits)
.-14271-07 (BBCB) IITT, MITCHELL, UNIVERSITY OF PENNSYLVANIA 383
TOWNE BUILDING/D3, PHILADELPHIA, PA. Physico-chemical properties
of tracheal mucus (dogs, frogs).
14306-07 (CVB) COWLEY, ALIEN W, JR, UNIVERSITY OF MISSISSIPPI
2500 N STATE STREET, JACKSON, MISS. Quantification of arterial pres-
sure control (dogs).
14313-07 (MET) QUARFORDT, STEVEN H, VETERANS ADMINISTRATION
HOSP. ROOM EB07, DURHAM. N C. Apoproteins of triglyceride rich
lipoproteins (human, squirrel monkeys, rats).
14344-07 (HEM) MORIN, ROBERT J, HARBOR GENERAL HOSPITAL 1124 W
CARSON STREET, TORRANCE, CALIF. Platelet function and' adenine
nucleotide metabolism (human).
-14378-07 (SGYA) BARBORIAK, JOSEPH J, MEDICAL COLLEGE OF
WISCONSIN, 561 NORTH 15TH STREET, MILWAUKEE, WIS. Lipemias and
reconstructive cardiac surgery (human).
-14388-07 (HEPA) ABBOUD. FRANCOIS M, UNIVERSITY OF IOWA COL-
LEGE OF MEDICINE, IOWA CITY, IOWA. Regulation of the circulaiion In
pathological states.
-I4388-07| 0151 (HEPA) ABBOUD, FRANCOIS M. Regulation of the circu-
lation in pathological states-Catecholamine release in potassium ion-
free contractures in the caudal artery
-14388-07 0152 (HEPA) ABBOUD, FRANCOIS M. Regulation of the circu-
lation in pathological states-Ion flux alterations in caudal artery in
SHR.
14388-07 0153 (HEPA) ABBOUD, FRANCOIS M. Regulation of the circu-
lation in pathological states-Subcellular distribution of calcium (rats)
14388-07 0154 (HEPA) ABBOUD, FRANCOIS M. Regulation of the circu^
lation in pathological states-Energetics of smooth muscle contraction
(rats).
14388-071 0155 (HEPA) ABBOUD, FRANCOIS M. Regulation of the circu-
lation in pathological states-Cardiopulmonary afferent activity, carotid
chemo-baroreceptor reflexes.
-14388-07' 0156 (HEPA) ABBOUD, FRANCOIS M. Regulation of the circu-
lation in pathological states-Blood pressure with drinking to in-
tracranial angiotensin II injections (rats)
■14388-07- 0157 (HEPA) ABBOUD, FRANCOIS M. Regulation of the circu-
lation in pathological states-Autoregulation of renal blood flow and
distribution in sodium excretion control
■14388-07 0158 (HEPA) ABBOUD, FRANCOIS M. Regulation of the circu-
lation in pathological states -Developmental aspect of abnormal
vascular reactivity (rats).
14388-07' 0159 (HEPA) ABBOUD, FRANCOIS M. Regulation of the circu-
lation in pathological states-Early drug and diet interventions and
blood pressure development (rats)
14388-07 0160 (HEPA) ABBOUD, FRANCOIS M. Regulation of the circu
lation in pathological states-Mechanism of the antihypertensive effect
of training (rats).
14388-07| 0161 (HEPA) ABBOUD, FRANCOIS M. Regulation of the circu-
lation in pathological states-Heterogeneity of left ventricular perfusion
in awake dogs.
.1 4388-07' 0162 (HEPA) ABBOUD, FRANCOIS M. Regulation of the circu-
lation in pathological states-Phasic coronary flow and myocardial per-
fusion in aortic regurgitation (dogs)
14388-07 0163 (HEPA) ABBOUD, FRANCOIS M. Regulation of the circu-
ation in pathological states-Adrenergic receptors in coronary vessels
(dogs).
14388-07 0164 (HEPA) ABBOUD, FRANCOIS M. Regulation of the circu-
,..,0. , '" "^""""B'^l states-Hyperkinetic heart syndrome (human)
14388-07 0165 (HEPA) ABBOUD. FRANCOIS M. Regulation of the circu-
lation in pathological states -Vascular resistance in experimental
atherosclerosis in Rhesus monkeys
14388-07 0166 (HEPA) ABBOUD. FRANCOIS M. Regulation of the circu-
lation in pathological states-Elastic changes in abdominal aorta with
atherosclerosis (Rhesus monkeys)
14388-07 0167 (HEPA) ABBOUD, FRANCOIS M. Regulation of the circu-
lation in pathological states-Increased reactivity of artery vascular
muscle in spontaneously hypertensive rat
14388-07 0168 (HEPA) HERMSMEYER, KENT. Regulation of the circula-
tion in pathological states-Ionic basis of depolarization (rats, tissue
14388-07 0172 (HEPA) ROSKOSKI, ROBERT, JR. Regulation of the circu-
lation in pathological states-cAMP-dependent protein kinase from
heart and vascular smooth muscle (guinea pigs)
""'""°''n,t.7' '"""?.' SWENSON, CHARLES A. Regulation of the cir-
cul^ajion in pathological states-Mechanisms of cardiac myosin AT-
.14388-07 0175 (HEPA) STEILWAGEN, EARIE. Regulation of the circula-
lon in pathological states-Functional studies of selected proteins
from cardiac muscle. k "remo
14388-07 0178 (HEPA) VAN ORDEN, I S, II.. Regulation of the circula-
tion in pathological states-Structural and functional consequences of
denervation (rats)
14388-07 0179 (HEPA) HERMSMEYER, KENT. Regulation of the circula-
tion in pathological states -Cultured muscle cells and their cross-in-
nervation in vitro (rats, sheep)
14388-07 0180 (HEPA) HEISTAD, DONALD D. Regulation of the circula-
tion in pathological states-Regulation of cerebral blood flow (dogs
monkeys).
'*"''°l°nl'„,*^";*\ '."!!'"'' ""''"" °- ''^«"'^«'»" °' '^= ^-^xlation
m^pathological states-Vasopressin in cardiovascular regulation (dogs,
14388-07 0184 (HEPA) MARK, ALLYN L. Regulation of the circulation in
pathological states-Vestibular reflexes in control of circulation
(human).
14388-07 0185 (HEPA) ABBOUD, FRANCOIS M. Regulation of the circu-
lation in pathological states-Reflex control of venous tone (human
rabbits, dogs).
14388-07 0186 (HEPA) MARK, ALLYN L. Regulation of the circulation in
pathological states-Angiotension in modulation of neurogenic
vasoconstriction.
541
M1Hl-14Sa8-07 01i7 (MIPA) IRODV, MICHAIl J. Rejulilion ol the circule
lion in pathological stales Histamine and cifculitoiy conttol
raiMl-M38t-07 0188 (HIPA) SMITH, ffttO O, JR. Regulation o( the circulation
in pathological states Renin angiotensin system in the sheep tetus
P0IHI-M38S-07 0190 (MEPA) WIUIAMSON, HAROID I. Regulation ol the cir
eolation in pathological states Mechanisms ol the tenal actions ol al
dosteione (lats)
POIHl-14388-07 019) (HEPA) STIINMETZ, PHIUP R. Regulation ol the circula
tion m pathological states Regulation ol chloride ttansport in epitheli
al membranes (turtles)
P01ML-1438S-07 0)93 (MEPA) Dl BONA, GERALD f. Regulation ol the circula
tion in pathological states Renal tubular secretion o( magnesium
(rats)
PO1HI-M388-07 0193 (HEPA) BHATNAGAR, RANBIR K. Regulation ol the crt
culation in pathological states Ontogenesis o( central nervous system
amines in hypertension (rats)
P01HL- 14388-07 0194 (HEPA) VAN ORDEN, L S, III. Regulation ot the circula
tion in pathological states-Dopaminebetahydroxylase localization and
release in hypertension
POIHl-14388-07 0195 (HEPA) ABBOUO, FRANCOIS M. Regulation ot the circu
lation in pathological states- General review of potential
pathophysiologic (actors in spontaneous hypertension
POIHl-1 4388-07 0196 (HEPA) BRODY, MICHAEL J. Regulation of the circula
tion in pathological states- Altered vascular responsiveness in spon.
taneous hypertension (rats)
POIHL-14388-07 0197 (HEPA) BRODY, MICHAEL J. Regulation of the circula
tion in pathological states -Altered vascular reactivity in pathogenesis
of spontaneous hypertension (rats).
POIHL-14388-07 0198 (HEPA) BRODY, MICHAEL J. Regulation of the circula
tion in pathological states-Humoral factors in vascular reactivity in
spontaneously hypertensive rats.
POIHL-14388-07 0199 (HEPA) BRODY, MICHAEL J. Regulation of the circula
tion in pathological states -Adrenergic stimulation in spontaneously
hypertensive rats,
POIHL-14388-07 0201 (HEPA) BRODY, MICHAEL J. Regulation of the circula
tion in pathological states -Central sympathetic discharge in spon-
taneously hypertensive rats.
POIHL-14388-07 0202 (HEPA) BRODY, MICHAEL J. Regulation of the circula-
tion in pathological states -Development ol hypertension in spontane-
ously hypertensive rats.
POIHl-14388-07 0203 (HEPA) BRODY, MICHAEL J. Regulation of the circula-
tion in pathological states-Activation of sympathetic nervous systems
in spontaneously hyperactive rats.
POIHL-14388-07 0204 (HEPA) BRODY, MICHAEL J. Regulation of the circula
tion in pathological states-Reflex control of vascular resistance in
spontaneously hypertensive rats.
POIHl-14388-07 0205 (HEPA) BRODY, MICHAEL J. Regulation of the circula
tion in pathological states-Pathogenesis of hypertension in spontane-
ously hypertensive rats.
POIHL-14388-07 0207 (HEPA) PHILLIPS, M IAN. Regulation of the circulation in
pathological states-Brain and renin-angiotension interaction in spon-
taneous hypertension (rats).
POIHL-14388-07 0208 (HEPA) ECKBERG, DWAIN L. Regulation of the circula
tion in pathological states-Baroreceptor reflex function in normal and
hypertensive man.
POIHL-14388-07 0209 (HEPA) ABBOUD, FRANCOIS M. Regulation of the circu
lation in pathological states -Neural regulation of vascular resistance
in human hypertension.
POIHL-14388-07 0210 (HEPA) MARK, AILYN L. Regulation of the circulation in
pathological states-Effects of dietary sodium on blood pressure and
vascular reactivity.
POIHL-14388-07 0211 (HEPA) ROSKOSKI, ROBERT, JR. Regulation of the circu
lation in pathological states -Choline acetyltransferase activity (rats).
POIHL-14388-07 0212 (HEPA) VAN ORDEN, L S, 111. Regulation of the circula
tion in pathological states-Role of dopamine in autonomic activity.
POIHL-14388-07 0213 (HEPA) SCHMID, PHILLIP G. Regulation of the circulation
in pathological states -Regulation of the heart and peripheral circula-
tion in heart failure.
POIHL-14388-07 0214 (HEPA) RIM, KWAN. Regulation of the circulation in
pathological states-Deformation pattern and stress analysis of the
left ventricle.
POIHL-14388-07 0215 (HEPA) FALSETTI, HERMAN L. Regulation of the Circula
tion in pathological states-Left ventricle model in pathophysiologic
POIHL-14388-07 0216 (HEPA) MARCUS, MELVIN L. Regulation of the circula
tion in pathological states-Development and regression of ventricular
hypertrophy (cats, rats).
POIHL-14388-07 0217 (HEPA) MARCUS, MELVIN L. Regulation of the circula
tion in pathological states-Fluid mechanics of aortic flow (dogs,
human).
POIHL-14388-07 0218 (HEPA) KERBER, RICHARD E. Regulation of the circula-
tion in pathological states-Regional myocardial dyskinesis-Cause as-
sessment and reduction (dogs).
POIHL-14388-07 0219 (HEPA) MARCUS, MELVIN L. Regulation of the circula
tion in pathological states-fi/lyocardial ischemia and infarction m
animals (dogs).
POIHL-14388-07 0220 (HEPA) MARK, ALLYN L. Regulation of the circulation in
pathological states -Pharmacology of the coronary circulation in man.
POIHL-14388-07 0221 (HEPA) DIANA, JOHN N. Regulation of the circulation in
pathological states -Experimental myocardial infarction (dogs).
POIHL-14388-07 0222 (HEPA) Dl BONA, GERALD F. Regulation of the circula-
tion in pathological states-Renal perfusion pressure in hypertension
(rats).
POIHL-14388-07 0223 (HEPA) FITZ, ANNETTE. Regulation of the circulation in
pathological states -Kallikrein-kinin system in hypertension (rats).
POIHL-14388-07 0224 (HEPA) LAWTON, WILLIAM. Regulation of the circulation
in pathological states-Kallikrein-kmin system in hypertension
(human).
POIHL-14388-07 0225 (HEPA) WILLIAMSON, HAROLD E. Regulation of the cir
culation in pathological states-Release of renal prostaglandins by
saluretic-diuretic agents (dogs).
POIHL-14388-07 0229 (HEPA) ABBOUD, FRANCOIS M. Regulation of the circu-
lation in pathological states-Mechanism of postural hypotension
(human).
P01HL-1438S
P01Hl-)438S
P01HL
P01HL
14388
14388
P01HL-14388
P01HL-14388
P01HL-
P01HL-
POIHl-
P01HL-
R01HL
14388-
14388-
14388
14388
-14397
P01HL-14414
P01HL-14414
P01HL-14414-<
P01HL-14414
P01HL-14414
P01HL-14414
P01HL-14414
POIHL-1 44 14
P01HL-14414
P01HL
POIHL
P01HL
14414.
.14414
■ 14414
R01HL-144S6
R01HL-14461
R01HL-14483
R01HL-14495
R01HL-14508
ROIHl-14509
R01HL-14523
R01HL
R01HL
ROIHt
14526
■ 14529
■ 14545
R01HL-14560
R01HL-14S71
P01HL-
P01HL.
POIHL
POIHL
PROJECT NUMBER AND INVESTIGATOR ADDRESS
.07 0230 (HEPA) MARK, AllYN L. Regulation ol the circulitwn m
pathological stales IHecIs of indomethacin in palienti with carcinoid
syndrome
.07 0231 (HEPA) HEISTAD, DONALD D. Regulation of the circuit
tion in pathological stale-, Mechansim ol cut»neou» vijodilatalion in
Pagel's disease of bone
-07 0232 (MEPA) HEISTAD, DONALD D. Regulation of the Circula
tion in pathological slates Idiopathic cyclic edema
-07 0233 (HEPA) ARMSTRONG, MARK L. Regulation ol the circu
lalion in pathological stales Pressure flow relationships after regrei
sion ol experimental atherosclerosis
07 0234 (HEPA) SCHMID, PHILLIP O. Regulation of the circulation
in pathological states Effects of antiarrhythmic drugs on the au
tonomic system (dogs)
07 9001 (HEPA) BRODY. MICHAEL J. Regulation o( the circula
tion in pathological states Core facility for hypertensive animal colony
(rats) , ^
■07 9002 (HEPA) VAN ORDEN, DIANNA. Regulation of the circu
lation in pathological states-Core immunoassay laboratory (rabbits)
-07 9003 (HEPA) INGRAM, F DUANE. Regulation of the circula
tion in pathological states Electron probe projects
-07 9004 (HEPA) ISACSON, PETER. Regulation of the circulation in
pathological states -Core biostatistics unit
-07 9005 (HEPA) ABBOUD, FRANCOIS M. Regulation of the circu
lation in pathological states-Core administration.
07 (PHRA) NEEDLEMAN, PHILIP, WASHINGTON UNIVERSITY. 660
SOUTH EUCLID. ST LOUIS. MO Hypertension -Angiotensin and
prostaglandin pharmacology (animals).
07 (HEPA) RENNIE, DONALD W, S U N Y AT BUFFALO. 122
SHERMAN HALL, BUFFALO, N Y Environmental influences on car-
diorespiratory and cellular functions
■07 0003 (HEPA) FARHI, LEON E. Environmental influences on car
diorespiratory and cellular functions-Exposure to abnormal gaseous
environments (human, dogs, rabbits).
■07 0004 (HEPA) PAGANELLI, CHARLES V. Environmental in
fluences on cardiorespiratory and cellular functions-Role of diffusion
in gas exchange (chicken egg).
07 0007 (HEPA) BISHOP, BEVERLY. Environmental influences on
cardiorespiratory and cellular functions -Neural control of respiration
(human, cats).
07 0008 (HEPA) RENNIE, DONALD W. Environmental influences
on cardiorespiratory and cellular functions-Energetics of swimming
(human).
■07 0010 (HEPA) HOGAN, PERRY M. Environmental influences on
cardiorespiratory and cellular functions-Pressure effects on cardiac
electrical phenomena (animals).
-07 0014 (HEPA) REEVES, ROBERT B. Environmental influences on
cardiorespiratory and cellular functions-Temperature and acid-base
status in tissues, cells, and subcellular system.
-07 0015 (HEPA) KRASNEY, JOHN. Environmental influences on
cardiorespiratory and cellular functions-Control of the cardiovascular
system (dogs).
.07 0016 (HEPA) PANGANELLI, C V. Environmental influences on
cardiorespiratory and cellular functions-Effects of pressure on mem-
brane and cellular function (human, rabbits).
.07 9001 (HEPA) FARHI, LEON E. Environmental influences on car-
diorespiratory and cellular functions-Laboratory core facility.
-07 9002 (HEPA) OLSZOWKA, ALBERT J. Environmental influences
on cardiorespiratory and cellular functions-Core-Computer facility.
-07 9003 (HEPA) MORIN, RICHARD A. Environmental influences
on cardiorespiratory and cellular functions -Machine and electronics
shop-Core facility.
■07 (CVA) FANBURG, BARRY L, NEW ENGLAND MED CTR HOSPITAL,
171 HARRISON AVENUE, BOSTON, MASS. Lung metabolism-Enzymes in
the pulmonary circulation (human, animals).
-08 (CVB) WILLIAMSON, JOHN R, UNIVERSITY OF PENNSYLVANIA,
BLDG G4, SCHOOL OF MEDICINE, PHILADELPHIA, PA. Cardiac metabol-
ism in heart failure (rats).
-08 (BIO) HINKLE, PETER C, CORNELL UNIVERSITY, BIOCHEM,
MOLECULAR & CELL BIO . ITHACA, N Y. Energy conservation in heart
mitochondria (cattle, E coli, human).
-05 (AFY) LEE, GEORGE C, S U N Y - AT BUFFALO. DEPT OF CIVIL
ENGINEERING, BUFFALO, N Y. Solid and structural mechanics of lungs
(mammals).
10 (BBCA) YONETANI, TAKASHI, UNIVERSITY OF PENNSYLVANIA,
37TH AND HAMILTON WALK, PHILADELPHIA, PA. Structure and function
of respiratory hemoproteins.
■07 (BBCB) MARSHALL, GARLAND R, WASHINGTON UNIVERSITY,
660 S EUCLID, ST LOUIS, MO. Hypertension-Chemistry and biophysics
of angiotensin.
-07 (PHY) FAY, FREDRIC S, UNIVERSITY OF MASSACHUSEHS, 55
LAKE AVE, NORTH, WORCESTER, MASS. Generation and regulation of
force in smooth muscle (animals).
.07 (CVB) FREGLY, MELVIN J, UNIVERSITY OF FLORIDA, BOX J-274
JHMHC GAINESVILLE, FLA. Oral contraceptives and hypertension (rats).
■07 (CVB) SAGAWA, KIICHI, JOHNS HOPKINS UNIVERSITY, 720 RUT-
LAND AVENUE, BALTIMORE, MD. Systems analysis of baroreflex (dogs).
.06 (CVA) NEWMAN, WALTER H, UNIVERSITY OF SOUTH CAROLINA,
80 BARRE STREET, CHARLESTON, S C. Mechanics of compensatory
ventricular hypertrophy (dogs).
-07 (CVB) BUNAG, RUBEN D, UNIVERSITY OF KANSAS. 39TH ST AT
RAINBOW BLVD, KANSAS CIH, KANS, Hypertension produced by sym-
pathetic dysfunction (human, rats).
-05 (SGYB) MC NAMARA, JOSEPH J, QUEENS MEDICAL CENTER.
1301 PUNCHBOWL STREET, HONOLULU, HAWAII. Myocardial preserva-
tion and coronary reperfusion (baboons, dogs).
-07 (HEPA) MEAD, JERE, HARVARD UNIVERSITY, 665 HUNTINGTON
AVENUE, BOSTON. MASS. Program project in respiratory mechanics.
-07 0001 (HEPA) HOPPIN, FREDERIC G. Program project in
respiratory mechanics-Micromechanics of the lung (dogs. rats).
■07 0002 (HEPA) DAWSON, STANLEY V. Program project in
respiratory mechanics-Airway aerodynamics (human, dogs).
■07 0003 (HEPA) GOLDMAN, MICHAEL D^ Program project in
respiratory mechanics -Chest wall mechanics and respiratory control
(human, dogs).
14580-
14580
-14580
■ 14580
>i^Ss
1
PROJECT NUMBER AND INVESTIGATOR ADDRESS
P0IHl.I4580.07 0005 (HEPA) MEAD, JERG. Program project in respiratory
tionthumanf ""'""'"' "" '"''"'*'"'" °' '"'^ of pulmonary func-
R01Hl.I4595.07 (HEM) WEISS, HARVEY J, ROOSEVELT HOSPITAL 428 WEST
( h'Jmaf rat^,; "'^ '°"'' ' ' ""'"' "'""''' ">* Platelet fu„l„
R01HI.I4614.07JCVA) GIBBONS, WAITER R, UNIVERSITY OF VERMONT GIVEN
"ear! (sheepr"""' '"'^^'"'^™N' "' ^°"^«' ""t™' <" contraction in
ROIHl-14637.05 (HEM) MC DONAID, TED P. UNIVERSITY OF TENNESSEE 1924
ALCOA HIGHWAY, KNOXVILLE. TENN. Thrombopoietin-lmmunoassay and
characterization (mice).
R01H1.14644-0S (SGYB) CORDAY, EUOT, CEOARSSINAI MEDICAL CENTER 8700
BEVERLY BLVD. LOS ANGELES, CALIF. Optimization diastoiraugmen
tation and systolic sink (dogs)
R01H1.1464S-07(CVA) MARTIN, ROY W, UNIVERSITY OF WASHINGTON, DEPT OF
ANESTHESIOLOGY, RN-IO , SEAHLE. WASH. Blood flow measurement
by ultrasonic catheter tip methods (human dogs)
ROI Hl-l 4646-05 (CVB) HOOD, WIlllAM B, JR, BOSTON CITY, 818 HARRISON
AVENUE, BOSTON, MASS. Pathophysiology of myocardial ischemia
(dogs. rats).
ROlHl-14651.05 (COM) JANZ, RONAID F, AEROSPACE CORPORATION, POST OF-
FICE BOX 92957. LOS ANGELES, CALIF. Mechanical behavior of left
ventricle (dogs. rats).
ROI Hl-1 4663-07 (CVA) NORTHWAY, WIUIAM H, JR, STANFORD UNIVERSITY
DEPARTMENT OF RADIOLOGY. STANFORD, CALIF. Pulmonary oxygen tox'
icity in newborn lung (human, mice).
R01Hl.14680.07 (BBCB) GURD, FRANK R, INDIANA UNIVERSITY. DEPARTMENT OF
CHEMISTRY, BLOOMINGTON, IND. Specific enrichment of myoglobins
for carbon 13 NMR (catacea)
ROI HH 4688-05 (CVB) SEIVESTER, RONAID H, RANCHO LOS AMIGOS HOSPITAL
7601 EAST IMPERIAL HIGHWAY, DOWNEY, CALIF. Myocardial assess'
ment by inverse electrocardiography (monkey)
R01HI.M692-06 (CVA) FAILAT. ROBERT J. INSTITUTE OF MEDICAL SCIENCES
POST OFFICE BOX 7999, SAN FRANCISCO. CALIF. Alpha 1 antitrypsin
deficiency and pulmonary disease (human)
ROIHI.14693.07 (CVA) CAIN, STEPHEN M. UNIVERSITY OF AUBAMA, UNIVERSITY
STATION, BIRMINGHAM, AW. Survival value of physiological responses
to hypoxia (dogs).
R01HH4697.07 (HEM) JAMIESON, GRAHAM A, AMERICAN NATIONAL RED
CROSS, 9312 OLD GEORGETOWN ROAD. BETHESDA, MD Role of
platelet membranes in hemostasis (human)
ROI HL-l 4700-05 (PTHA) GAIDSTON. MORTON, NEW YORK UNIVERSITY 550
FIRST AVENUE. NEW YORK, N Y. Humoral and lung protease an
tiprotease role in obstructive disease (human)
ROI HI- 14706-07 (CVA) WIlDENTHAl, C KERN, UNIVERSITY OF TEXAS 5323
HARRY MINES BOULEVARD, DALLAS. TEX. Fetal hearts in organ cultur
(mice).
ROlHl.14713-06 (CVA) lOUD, ALDEN V, NEW YORK MEDICAL COLLEGE BASIC
SCIENCE BUILDING, VALHALU, N Y. Hypothermia and the heart (bats
guinea pigs).
ROIHl-14717.06 (CVB) lAKS, MICHAEL M, HARBOR GENERAL HOSPITAL 1000
WEST CARSON STREET, TORRANCE, CALIF. Hemodynamics and heart
structure -Ventricular overload (dogs)
ROI HH 4720.08 (GMB) BANK, NORMAN, MONTEFIORE HOSPITAL & MED CTR
V'?,.^™"^' ^''°^''' " ' ^^^'"^^ «°^«'"i"« "^e renal exc e^
tion of acid (humans, rats)
R01HI.14730.07 (MET) HUU, FRANKUN E, WAYNE STATE UNIVERSITY, 357 MEDI-
CAL RESEARCH BUILDING , DETROIT, MICH. Fatty acid beta-oxidation
in normal and ischemic hearts (rabbits)
ROIHI.14739.06 (HEM) LERNER, ROBERT G, NEW YORK MEDICAL COLLEGE 1249
H AVENUE, NEW YORK. N Y. The role of leukocytes in thr m ti
disease (human, dogs).
R01HH4775-08 (PHRA) WEISS, GEORGE B, UNIVERSITY OF TEXAS 5323 HARRY
MINES BOULEVARD, OALUS, TEX. Mechanisms of drug action il
vascular smooth muscle (dog, rabbits)
ROlHL.14778-10 (PC) TRAVIS, JAMES, UNIVERSITY OF GEORGIA, DEPARTMENT OF
BIOCHEMISTRY, ATHENS. GA. Proteolytic enzymes and inhibitors in
lung disease (mammals, human)
ROlHt-14781-08 (SSS) SPECTOR, ARTHUR A, UNIVERSITY OF IOWA DEPT OF
tLfce) '' '°^' "''■ '°™- ^""'^ ''""""""' '" '"^"""^'''" "'1^
ROlHl.14785-07 (SSS) REID^ JOHN M, PROVIDENCE MEDICAL CENTER, 556 18TH
AVENUE, SEAHLE, WASH. Ultrasonic scattering for tissue character za
tion (dogs, cattle, human),
ROIHI.14799.07 (SGYB) REEMTSMA, KEITH, DEPARTMENT OF SURGERY 630
WEST 168TH STREET, NEW YORK, N Y. Cardiac heterotransplantation
Immunologic modification (mice, rat)
R01HI-I4820-07 (PHY) SOIOMON, ARTHUR K, HARVARD MEDICAL SCHOOL 25
SHAHUCK STREET, BOSTON, MASS. Factors affecting physiology of
biological membranes (human)
ROIHl-14826-05 (RAD) WATTS, RICHARD S, VETERAN ADMINISTRATION HOSP
2100 RIDGECREST DRIVE. S E, ALBUQUERQUE, N MEX External
isotope assay of atherosclerosis (rats, rabbits)
R01Ht.I4832-06 (CVA) ERTEl, ROBERT J, UNIVERSITY OF PIHSBURGH 1100
SALK HALL, PITTSBURGH. PA. Myocardial cells-Autonomic and
rhythmic mechanisms (chick embryo, rats)
ROIHl.14844.06 (PTHA) BOAT, THOMAS f, RAINBOW BABIES/CHILDRENS HOSP
2103 ADELBERT ROAD, CLEVEUND, OHIO. Mucous glycoprotein in
human respiratory epithelium (also wheat)
ROIHI.14847.07 (HEM) BEU, ROBERT G, UNIVERSITY OF RHODE ISUND MOR-
RILL HALL, KINGSTON, R I. Mechanism of action of vitamin K and an-
ticoagulants (rats).
R0IHI-I48S4-07 (AFY) HllDEBRANDT, JACOB, VIRGINIA MASON RESEARCH
CENTER. 1000 SENECA STREET, SEATTLE, WASH. Lung and tissue
mechanics (monkeys, dogs).
ROI HI. 1 4865-07 (PC) UENER, IRVIN E, UNIVERSITY OF MINNESOTA, DEPARTMENT
OF BIOCHEMISTRY, ST PAUL, MINN. Biochemical studies on the
pathogenesis of emphysema (human, rats)
R01HL-14870-06 (CVA) KUNZ, ALBERT I, OHIO STATE UNIVERSITY 333 WEST
OTH AVENUE, COLUMBUS, OHIO. Dynamics of oxygen 'and cal
dioxide regulation (animals)
ROlHl.14890-07 (HEM) SILVER, MEIVIN J, CARDEZA FOUNDATION, 1015 WALNUT
STREET, PHILADELPHIA, PA. Platelet prostaglandins (human, rabbits)
542
ROI HI
ROIHL
R01HL
ROIHL.
ROIHL-
ROIHL-
ROIHL-
POIHL
POIHI.
POIHL
POIHL-
POIHL-
POIHL-
POIHI
POIHL
POIHL
POIHI.
POIHL-
POIHL-
POIHL-
POIHL
POIHL
POIHL-
POIHL.
ROIHL-
ROI HI-
ROIHL
ROIHL.
ROI HI.
ROIHL-
ROIHL
P50HL
P50HL
P50HL
P50HL
P50HL-
P50HL
P50HL
P50HL
P50HI-
P50HL
-14899-07 (CVA) CRANEFIEID, PAUL F, ROCKEFELLER UNIVERSITY 1230
YORK AVENUE, NEW YORK, N Y. Mechanism and prevention of cardiac
arrhythmias (dogs).
■14903-07 (CVA) SAGAWA, KIICHI, JOHNS HOPKINS SCH OF MEDICINE
720 RUTLAND AVENUE. BALTIMORE. MD. A new index of cardiac con-
tractility (human, dogs, baboons).
•14913-06 (CVB) IWAI, JUNICHI, BROOKHAVEN NATIONAL LABORATORY AS-
SOCIATED UNIVERSITIES, INC, UPTON, N Y. Hypertension -Genetic in-
fluence of kidney (rats).
14914-06 (GMB) BLANTZ, ROLAND C, VETERANS ADMINISTRATION HOSP
3350 LA JOLLA VILLAGE DRIVE, SAN DIEGO, CALIF. Autoregulation of
glomerular filtration rate (rats).
14938-06 (BBCB) RICHARDS, E GlEN, VETERANS ADMINISTRATION HOSP
4500 SOUTH UNCASTER ROAD, DALLAS, TEX. Contractile proteins oi
heart muscle (dogs, rabbits)
14944-07 (CVB) HOLIENBERG, NORMAN K, PETER BENT BRIGHAM
HOSPITAL, 721 HUNTINGTON AVENUE. BOSTON. MASS. Renal vascular
reactivity in hypertensive patient
14967-06 (CVA) WHIPP, BRIAN J, HARBOR GENERAL HOSPITAL. 1000
WEST CARSON STREET, TORRANCE, CALIF. Chemoreceptor function in
dynamic ventilatory control (human, dogs)
■14985-07 (HEPA) GROVER, ROBERT F, UNIV OF COLORADO MED CTR
4200 EAST NINTH AVENUE, DENVER, COLO. Adaptation to hypoxia
14985-07 0002 (HEPA) GROVER, ROBERT F. Adaptation to hypoxia- Ox-
ygen transport in man at high altitude
14985-07 0003 (HEPA) WEIl, JOHN V. Adaptation to hypoxia -Hypoxia
and oxygen transport (human, dogs)
14985-07 0004 (HEPA) WEIL, JOHN V. Adaptation to hypoxia -Control of
breathing in respiratory failure (human, dogs)
14985-07 0005 (HEPA) WAGNER, WIITZ W. Adaptation to hypoxia -Con-
trol mechanisms in the pulmonary microcirculation (animals)
-14985-07 0007 (HEPA) REEVES, JOHN T. Adaptation to hypoxia -Control
, ..»., pulmonary circulation, histamine and the sympathetics (animals)
-14985-07 0008 (HEPA) WEIl, JOHN V. Adaptation to hypoxia-Ventilatory
drive and exercise capacity (human, dogs)
■14985-07 0009 (HEPA) WEIL, JOHN V. Adaptation to hypoxia-lnfluence
of chemosensitivity on control of breathing during sleep (human
dogs).
•14985-07 0010 (HEPA) REEVES, JOHN T. Adaptation to hypoxia -Pulmo-
nary mast cell (animals).
14985-07 0011 (HEPA) REEVES, JOHN T. Adaptation to hypcia-
,^o.. ^'^"'^♦aglandins in the control of the pulmonary circulation (animals)
-14985.07 0012 (HEPA) MCMURTRY, IVAN F. Adaptation to hypoxia-
Uircct effect of hypoxia on pulmonary vascular smooth muscle (rats
dogs).
■14985-07 0013 (HEPA) WEIl, JOHN V. Adaptation to hypoxla-Chronic
mountain sickness (men)
14985-07 0014 (HEPA) REEVES, JOHN T. Adaptation to hypoxia-High al-
titude pulmonary edema (human, rats, dogs)
14985-07 0015 (HEPA) GROVER, ROBERT F. Adaptation to hypoxia-
Pregnancy at high altitude (human, animals)
.14985-07 0016 (HEPA) GROVER. ROBERT F. Adaptation to hypoxia-Ad^
mmistrative core.
'"""""la^o^rltorier"*' °"°''"' "°"" '' *"""'*'"" '" *^^0'>»'-<^'"0
■14985.07 0018 (HEPA) GROVER, ROBERT F. Adaptation to hypoxia-
Bioengineering core.
• 14990.07 (MET) BENSADOUN, ANDRE, CORNELL UNIVERSITY 24?
Sns)"*'" '™'"' ' ' ''"' ♦""^"'"^ in avian spec'es
•14992.07 (HEM) FEINMAN, RICHARD D, S U N Y ■ DOWNSTATE MFO
CTR, 450 CLARKSON AVENUE, BROOKLYN, N Y. Mechanrm o, thi
bin action (human)
'"""°'RESH*rp;TrB*''nn^,'-.?.*' ""''"^'^ °^ "'^SOURI, DALTON
RESEARCH CENTER. COLUMBIA, MO. Biochemical pharmacology of
guanylate cyclase in lung (cattle, rats)
15013.07 (BIO) FISHER, ARON B, UNIVERSITY OF PENNSYLVANIA A402
RICHARDS BUILDING G4, PHIUDELPHIA, PA. Lung oxidative metabo
ism and energy production (rodents, rabbits)
'15016.07 (RAD) GRAMIAK, RAYMOND, UNIVERSITY OF ROCHFSTFR fini
ELMWOOD AVENUE, ROCHESTER, NY. New clept f „ ca d,ac
trasound technology (human).
15026.12 (GEN) SMITH, KIRBY D, JOHNS HOPKINS UNIVERSITY 720 RUT
UN AVENUE, BALTIMORE, MD. Quantitative genetic cont!oi of rotein
synthesis (human, primates, mammals)
'"^'■°' Sp"^nZ«r1?.'fcT"""" "■ ^""*NS ADMINISTRATION
HOSP, 50 IRVING STREET. N W, WASHINGTON, D C. Digital computer
analysis of the electrocardiogram (human) "^
■15061-07 (SRC) FISHMAN, ALFRED P, HOSP UNIVERSITY OF PENNSYLVANI
3m & SPRUCE STREET, PHILADELPHIA, PA. Response of lung to inju:
•15061-07 0002 (SRC) FISHER, ARON B. Response of lung to injury-Ox-
ida^ve metabolism, phospholipid synthesis, and response to toxins
15061-07 0004 (SRC) KEFAUDES, NICHOLAS A. Response of lung to in-
, c«.. '""'•■^'ochemical abnormalities in connective tissues (rats)
15061.07 0005 (SRC) COBURN, RONAID F. Response of lung to injury-
Airway smooth muscle in health and disease (dogs, guinea pigs)
r„°mT "?^' •'°«'^NDS, DAVID T. Response of lung'^iury-
Complement synthesis by pulmonary macrophages (guinea pigs,
■15061.07 0007 (SRC) ROWLANDS, DAVID T. Response of lung to injury-
, i:n^, „•, r'" '°" '"' ""'aKocytosis in normal and diseased lungs
•15061.07 0009 (SRC) ROWLANDS, DAVID T. Response of lung to injury-
Alveolar macrophages (human, rabbits)
15061-07 0010 (SRC) REIF, JOHN S. Response of lung to injury-An
ammal model system for the study of bronchiolitis and its sequellae
15061-07 0012 (SRC) CHANCE, BRITTON. Response of lung to injury-
Hyperbaric oxygen, carbon monoxide, and ozone or peroxide toxicity
15061.07 0013 (SRC) FORSTER, ROBERT E. Response of lung to injury-
Exchange transfusion in infants with respiratory distress syndrome
(human, sheep).
543
PS0HI-1S063-07 (iHC) WlSSlIt, BOSIIIT W, UNIVERSIIY Of CHICAGO. 950 tASl
b9TH STREtl. CHICAGO. ILl Study ol lipopioHins, artety wall, and
atheioscltiosis
PS0HL-IS062-07 0001 (S«C) SCANU. ANOEIO M. Study ol lipoproteins, artaiv
wall, and alheiosclerosis Structure and molecular interactions ol
serum lipoproteins (human, monkey)
P50HL-1 5063-07 0007 (SHC) KHDV, FERENC J. Study o( lipoproteins, artery
wall, and altierosclerosis Pliysical diemijlry ol lipidprotaln Inlwac-
tion (human)
P50HI-1 5062-07 0008 (SRC) lAW. JOHN H. Study of lipoproteins, artery wall,
and atherosclerosis Lipid modilying enzymes (human, monKey)
PSOHl-l 5062-07 0009 (SRC) OETI, GODFREY S. Study ol lipoproteins, artery
wall, and atherosclerosis-Plasma lipoprotein biosynthesis (Rhesus
monkeys)
P50HI-1 5062-07 0012 (SRC) WISSIER, ROBERT W. Study ol lipoproteins, artery
wall, and atherosclerosis Lipoprotein stimulation ol arterial smooth
muscle cell prolileration (mammals)
P50HL- 15062-07 0013 (SRC) RUBENSTEIN, ARTHUR M. Study ol lipoproteins,
artery wall, and atherosclerosis Radioimmunoassay ol apolipoproteins
(human, monkeys)
P50MI-1 5062-07 0018 (SRC) WISSIER, ROBERT W. Study ol lipoproteins, artery
wall, and atherosclerosis-Reversal ol atherosclerosis in monkeys
P50HI- 15062-07 0019 (SRC) WISSLER, ROBERT W. Study ol lipoproteins, artery
wall, and atherosclerosis-Factors regulating lipoprotein-smooth muscle
cell interaction (monkey)
P50HI-1 5062-07 0020 (SRC) GUVGOV, SEYMOUR. Study ol lipoproteins, artery
wall, and atherosclerosis -Artery wall reactions -Elevated pressure and
hyperlipemia (monkey)
P50HI- 15062-07 0021 (SRC) WISSIER, ROBERT W. Study ol lipoproteins, artery
wall, and atherosclerosis -Core laboratories.
P50HH 5092-07 (SRC) WEILl, HANS, TUUNE UNIVERSITY, 1430 TULANE AVENUE,
NEW ORLEANS. LA Immune and librotic response to occupational en-
vironments.
P50HH5092-07 0001 (SRC) ALLEN, GARY C. Immune and librotic response to
occupational environments-X-ray diHraction study-Dust exposure in
asbestos cement products manulacturing.
P50HL-1 5092-07 0002 (SRC) ZISKIND, MORTON M. Immune and librotic
response to occupational environments -Longitudinal study of sand-
blasters silicosis (human).
PSOHL-1 5092-07 0005 (SRC) BUTCHER, BRIAN T. Immune and librotic response
to occupational environments -Respiratory and immunologic evaluation
ol toluene diisocyanate exposure (human).
P50HL-1 5092-07 0006 (SRC) WILSON, MERLIN R, JR. Immune and librotic
response to occupational environments -Immunologic studies in silico-
sis (human, rabbits, hamsters, guinea pigs)
P50HL-1 5092-07 0007 (SRC) WEILL, HANS. Immune and librotic response to oc-
cupational environments-Asbestosis-Cellular immunity, structure and
mineral localization (human).
P50HL- 15092-07 0008 (SRC) GAUMER, H RICHARD. Immune and librotic
response to occupational environments-Animal models of asbestosis
(hamsters).
PSOHL-1 5092-07 0010 (SRC) DHARMARAJAN, VENKATRAM. Immune and
librotic response to occupational environments-Characterization of
toluene diisocyanate in industrial environments.
P50HL-1 5092-07 0011 (SRC) LEHRER, SAMUEL B. Immune and fibrotic response
to occupational environments-Respiratory and immunologic responses
in coffee plant workers.
P50HL-1 5092-07 0012 (SRC) JONES, ROBERT N. Immune and fibrotic response
to occupational environments-Longitudinal evaluation of workers ex-
posed to cotton dust
P50HL-1 5092-07 0013 (SRC) WEILl, HANS. Immune and fibrotic response to oc-
cupational environments-Epidemiology core resource.
P50HL-1 5092-07 0014 (SRC) BUTCHER, BRIAN T. Immune and fibrotic response
to occupational environments-Clinical immunology core resource.
P50HL-1 5 103-07 (SRC) BERENSON, GERALD S, LOUISIANA STATE UNIVERSITY,
1542 TULANE AVENUE, NEW ORLEANS, U. A/S SCOR-Early natural
history of arteriosclerosis.
P50HL-1 5 103-07 0001 (SRC) BERENSON, GERALD S. A/S SCOR-Early natural
history of arteriosclerosis-Clinical research -Bogalusa heart study
(children).
P50HL-1 5103-07 0013 (SRC) SRINIVASAN, S R. A/S SCOR-Early natural history
ol arteriosclerosis-Experimental models of atherosclerosis (monkeys).
P50HL-15103-07 0014 (SRC) RADHAKRiSHNAMURTHY, B. A/S SCOR Early
natural history of arteriosclerosis-Biochemistry of atherosclerotic le-
sions (monkeys, human, cattle).
R01HL-15104-07 (BIO) GLASS, RICHARD S, UNIVERSITY OF ARIZONA, DEPART-
MENT OF CHEMISTRY, TUCSON, ARIZ. A mechanism for oxidative
phosphorylation.
R01HL-1S124-05 (CVB) BALDWIN, DAVID S, NEW YORK UNIVERSITY MED CTR,
550 FIRST AVENUE, NEW YORK, N Y. Genesis of hypertension in renal
disease (human, dogs).
R01HL-15125-07 (PBC) YOSHIDA, AKIRA Y, CITY OF HOPE NAT MEDICAL CTR,
1500 EAST DUARTE ROAD, OUARTE, CALIF. Molecular pathology ol
genetic disorders in man.
ROlHL-151 55-05 (BBCB) FORSMAN, WILLIAM C, UNIVERSITY OF PENNSYLVANIA.
398 TOWNE BUILDING. PHILADELPHIA, PA. Rheology of pulmonary
secretions (dogs).
P60HL-1 51 57-07 (SRC) ROMAN, STANFORD A, JR, BOSTON CITY HOSPITAL, 818
HARRISON AVENUE, BOSTON, MASS. Comprehensive center for sickle
cell disease.
P60HL-1 5 157-07 0001 (SRC) ADAMS, WILLIAM H. Comprehensive center for
sickle cell disease-Screening program (human).
P60HL-15157-07 0002 (SRC) ROMAN, STANFORD A, JR. Comprehensive center
for sickle cell disease-Central data bank and research file.
P60HL-1S157-07 0003 (SRC) ROMAN, STANFORD A, JR. Comprehensive center
for sickle cell disease-Public education.
P60HL-1 5 157-07 0009 (SRC) PALEK, JIRI. Comprehensive center for sickle cell
disease-Red cell membrane alterations during sickling (human).
P60HI-1 5 157-07 0011 (SRC) RICH, ALEXANDER. Comprehensive center for
sickle cell disease-Development of specific anti-sickling compound
(human).
P60HL-1 5 157-07 0012 (SRC) DESFORGES, JANE F. Comprehensive center for
sickle cell disease-Sickling and intracellular pH (human).
PROJECT NUMBER AND INVtSTIOATOR ADDRESS
P60HLISIS7-07 0018 (SRC) NATHAN, DAVID Comprehensive center lor iickl*
cell disease Red blood cell membrane physiology in sickle cell
anemia (human)
P60HL-1 5 158-07 (SRC) HUISMAN. TITUS H, MEDICAL COLLECf Of CEORGIA, AU
CUSIA, GA Comprehensive sickle cell center
P60HL-1 51 58-07 0004 (SRC) OIUMAN, PRISCILLA A. Comproheni.ve sickle coll
center Expression ol abnormal hemoglobin synthesis in the neonate
and young child
P60HL-1 51 58-07 0008 (SRC) HUISMAN, TITUS H J. Compreheniivt Jickle cell
center Core laboratory ol the center
P60HL-1 51 58-07 0009 (SRC) MILNER, PAUL F. Comprehensive sickle cell center
Counseling and social services
P60HL-1 5 158-07 0010 (SRC) HARRIS, HERMAN F. Comprehensive sickle cell
center Tutorial service lor sickle cell anemia patients
P60HL-1 51 58-07 0011 (SRC) MILNER, PAUL F. Comprehensive Sickle cell center
Clinical services Adult patients
P60HL-1 5 158-07 0012 (SRC) GluwAN, PRISCILLA A. Comprehensive iickle cell
center Clinical services Pediatric patients
P60HL-1 5 158-07 0014 (SRC) AMMA, EIWER I. Comprehensive sickle cell center
Mechanism ol sickling in human and deer hemoglobins.
P60HL-1 51 58-07 0016 (SRC) HUISMAN, TITUS H J. Comprehensive sickle cell
center Biochemical studies in sickle cell anemia (human)
P60HL-1 51 58-07 0020 (SRC) GARVER, FREDERICK A. Comprehensive Sickle cell
center-lmmunochemical investigation ol hemoglobin variants
(human)
P60HL-1 5 158-07 0025 (SRC) STRONG, WlUlAM B. Comprehensive sickle cell
center Cardiovascular evaluation ol children with sickle cell disease
(human).
P60HL-1 5 158-07 0027 (SRC) HARRIS. HERMAN F. Comprehensive sickle cell
center -Community advisory board -Nancy Cobb house.
P60HL-15158-07 0028 (SRC) HUISMAN, TITUS H J. Comprehensive sickle cell
center-Education.
P60HL-1 5 160-07 (SRC) SCOTT, ROLAND B, HOWARD UNIVERSITY, COLLEGE OF
MEDICINE. WASHINGTON, D C Center for sickle cell disease.
P60HL-1 5 160-07 0003 (SRC) MURRAY, ROBERT F, JR. Center for sickle cell dis
ease-Genetic counseling in hemoglobinopathies-Dimensions, effective-
ness.
P60HI-1 5 160-07 0008 (SRC) lEE, TED C K. Center lor sickle cell disease-lso
cyanate derivatives and hemoglobin S association (human, rat).
P60HL-1 51 60-07 0009 (SRC) UY, CORAZON G. Center for sickle cell disease-
Natural history of sickle cell disease (human).
P60HL-1 51 60-07 0011 (SRC) CASTRO, OSWALDO. Center for sickle cell dis
ease-Study of human sickle cells in an animal model (rats).
P60HL-1 51 60-07 0012 (SRC) CASTRO, OSWALDO. Center for sickle cell dis
ease-Core laboratories.
P60HL-1 5 160-07 0013 (SRC) HEADINGS, VERLE E. Center for sickle cell dis-
ease-lmmunochemical diagnosis of hemoglobinopathies (infants).
P60HL-1 51 60-07 0014 (SRC) CASTRO, OSWALDO. Center for sickle cell dis
ease-Replacement therapy of opsonin deficiency in sickle cell anemia
(children).
P60HL-1 5 160-07 0015 (SRC) YOUNG, ROSCOE C. Center for sickle cell dis-
ease-Lung function abnormalities in sickle cell hemoglobinopathies
(human).
P60HL-1 51 60-07 0016 (SRC) MILLER, RUSSELL L. Center for sickle cell disease-
Kinin and plasmin system in sickle cell disease (human).
P60HL-1 51 60-07 0017 (SRC) SCOTT, ROLAND B. Center for sickle cell disease-
Demonstration-Education, screening, counseling, patient care.
P60H1.1 51 62-07 (SRC) HAYWOOD, L JULIAN, UNIV OF SOUTHERN CALIFORNIA,
1200 NORTH STATE ST - BOX 305 , LOS ANGELES, CALIF. Comprehen-
sive sickle cell center.
P60HL-1 51 62-07 0001 (SRC) POWARS, DARLEEN R. Comprehensive sickle cell
center-Core program -Patient care.
P60HL-1 51 62-07 0007 (SRC) HAYWOOD, L JULIAN. Comprehensive sickle cell
center-Core program-Demographic studies (human).
P60HL-1 5 162-07 0010 (SRC) VAVASSEUR, JUNE. Comprehensive sickle cell
center-Core program -Community outreach and education program.
P60HL-1 51 62-07 0011 (SRC) POWARS, DARLEEN R. Comprehensive sickle cell
center-Core program-Genetic counseling and diagnostic screening.
P60HL-1 51 62-07 0017 (SRC) RICHARDS, JOHN H. Comprehensive sickle cell
center-Hemoglobin, erythrocytes and sickle cell anemia (human, rab-
bit).
P60HL-1 51 62-07 0018 (SRC) SCHROEDER, WALTER A. Comprehensive sickle
cell center-Biochemical and genetic studies of sickle cell anemia
(human).
P60HL-1 51 62-07 0019 (SRC) MEISEUVtAN, HERBERT J. Comprehensive sickle
cell center-RBC-Blood rheology in sickle cell anemia and related dis-
orders (human, animal).
P60HI-1 51 62-07 0020 (SRC) BAKER, RICHARD. Comprehensive sickle cell
center-Biophysical studies of normal and sickle red cells (human).
P60HL-1 51 62-07 0021 (SRC) OVERTURF, GARY D. Comprehensive sickle cell
center-Pneumococcal vaccine in sickle cell disease (children).
P60HL-1 5 168-07 (SRC) RABB, MAURICE F, UNIVERSITY OF ILLINOIS. 1919 W
TAYLOR ST, CHICAGO, ILL. Comprehensive sickle cell disease center.
P60HL-1 51 68-07 0001 (SRC) HELLER, PAUL. Comprehensive sickle cell disease
center-Screening program (human).
P60HL-1 51 68-07 0002 (SRC) HELLER, PAUL. Comprehensive sickle cell disease
center-Patient care.
P60HL-1 5 168-07 0003 (SRC) DESIMONE, JOSEPH. Comprehensive sickle cell
disease center-Sickle cell education and training program.
P60HL-1 51 68-07 0005 (SRC) GOLDBERG, MORTON F. Comprehensive sickle
cell disease center-Ophthalmology (human, rabbits, monkeys).
P60HL-1 51 68-07 0006 (SRC) RABB, MAURICE F. Comprehensive sickle cell dis-
ease center-Core center.
P60HL-1 51 68-07 0009 (SRC) JOHNSON, MICHAEL E. Comprehensive sickle cell
disease center-Spin-label study of sickling (human).
P60HL-1 5 168-07 0010 (SRC) HONIG, GEORGE R. Comprehensive sickle cell dis-
ease center-Sickle cell center project (children).
P60HL-1 51 69-05 (SRC) KRAUS, ALFRED P, UNIVERSITY OF TENNESSEE, 800
MADISON AVE, MEMPHIS, TENN. Support for center for sickle cell dis-
ease.
P60HL-1 51 69-05 0009 (SRC) BISNO, ALAN L. Support lor center for sickle cell
disease-Infections in sickle cell anemia (human).
P60HI-1 51 69-05 0012 (SRC) PHILLIPS, JERRY C. Support lor center for sickle
cell disease -Evaluation of the incidence of cholelithiasis in sickle cell
disease (human).
PROJECT NUMBER AND INVESTIGATOR ADDRESS
P60HIO5169-05 00,4 (SRC) ANDERSON. lEWIS D. Support for center for
(hurlian) """"•"'"'"P^^'''' aspects of sickle cell disease
P60Hl.15I69.05 0015 (SRC) DAVIS, HARRY I. Support for center for sickle cell
di"asT(hum°aT'°'°** °' '""' """""""^ '"'''*""" '" ^''^'^ ""
P60Hl.,S,69-05 00,7 (SRC) DIGGS. I W. Support for center for sickle cell dis-
P60HI 15,69 OS om» ,m' """'" ^'""'^ °' ''^"^ "" O'S^^^e '" '"e home.
P60Hl.,5,69.05 00,8 (SRC) KRAUS. LORRAINE M. Support for center for sickle
P60HL ,S1*0 n^n','™;""" °" ''""' "" ""^''^ <''""'^"' ^3tS. dogs).
P60HI., 5, 69-05 00,9 (SRC) KRAUS. ALFRED P. Support for center for sickle
disease-Central screening and reference laboratory
P60HL.,5,69.05 002, (SRC) KRAUS. ALFRED P. Support for center for sickle
cell disease-Multidisciplinary module system for education, screening
and counseling. ^
P60HI-1 5 170-05 (SRC) JONES. CYRIL J. STATE UNIVERSITY OF NEW YORK 450
CLARKSON AVENUE. BROOKLYN. N Y. Support for center7or sickle c H
anemia.
P60HL.15170-05 000, (SRC) HOLDEN, DOROTHY M. Support for center for
sickle cell anemia-Adult clinical services
P60HL-,5,70-05 0002 (SRC) HOLDEN. DOROTHY M. Support for center for
o.c„^. ^^ ^ "" anemia-Adult services-Testing programs
P60Hl-,5,70.05 0003 (SRC) HOLDEN, DOROTHY m' Support for center for
PAAu. ,c,,« «/' anemia-Adult services-Educational programs.
P60HL.,5,70-05 0006 (SRC) BROWN. AUDREY K. Support for center for sickle
o^-^. " anemia-Pediatric services-Comprehensive clinic
P60HU,5,70.05 0007 (SRC) BROWN. AUDREY K. Support for center for sickle
cell anemia -Pediatric services-Screening program
P60HL.,5,70-0S 0008 (SRC) BROWN. AUDREY K. Support for center for sickle
cell anemia-Pediatric services-Education program
P60Hl-,5, 70-05 00,7 (SRC) LEVERE. RICHARD D. Support for center for sickle
..c«u. .,,, " anemia-Control of hemoglobulin synthesis (human)
P60HL-,5,70-0S 00,9 (SRC) DIAMOND. HERBERT S. Support for center for
sickle cell anemia-Renal handling of uric acid in sickle cell anemia
(human).
P60Hl-,S,70-05 0023 (SRC) DOSIK. HARVEY. Support for center for sickle cell
anemia-Comprehensive sickle cell clinic
P60HL-,5,70.05 0030 (SRC) HOLDEN. DOROTHY M. Support for center for
sickle cell anemia-Adult services-Counseling program
R0,HL-,5,74-06 (EDC) STAMLER, JEREMIAH. NORTHWESTERN UNIVERSITY 303
E CHICAGO AVENUE, CHICAGO. ILL. CV disease epidemiology-Sec nd
generation studies (human)
ROIHI.,5190.07 (CVB) GALLAGHER. JOHN J. DUKE UNIVERSITY, BOX 3022.
DURHAM, N C. Physiological basis of arrhythmias and their therapy
(human). "
R0,HL-,5,9,-07 (EDC) CORNFIELD. JEROME. GEORGE WASHINGTON UNIVERSITY
79 OLD GEORGETOWN ROAD, BETHESDA, MD. Multiparameter
methods for cardiovascular research
P0,HL.,5,94-07 (HERA) KLOCKE, FRANCIS J. S U N Y ■ AT BUFFALO 462
GRIDER STREET, BUFFALO, N Y. Pathophysiology of cardiopulmonary
dysfunction. '
P0,HL.,5, 94-07 000, (HEPA) KLOCKE. FRANCIS J. Pathophysiology of car-
diopulmonary dysfunction-Coronary circulation, venous drainage and
collateral flow (human, dogs)
P0,HL-,5,94-07 0004 (HEPA) HOGAN. PERRY. Pathophysiology of cardiopulmo-
nary dys unction-Specialized electrophysiology fibers-Electrogenic
basis of glycosides (mammals)
P0,Hl-,5, 94-07 0006 (HEPA) KLOCKE. ROBERT A. Pathophysiology of car-
diopulmonary dysfunction-Kinetics of gas exchange-Velocity of Bohr
effect in erythrocytes (human)
P0,HU,S,94.07 0009 (HEPA) KLOCKE. ROBERT A. Pathophysiology of car-
diopulmonary dysfunction-Kinetics of gas exchange-Diffusion and
erythrocytes reaction rates (human, dogs)
P0,HL.,5, 94-07 00,, (HEPA) KLOCKE. ROBERT A. Pathophysiology of car-
diopulmonary dysfunction-Distribution of ventilation-Oxygen effects on
intrapulmonary shunting (human)
PO,HL-, 5, 94-07 00,7 (HEPA) KLOCKE. FRANCIS J. Pathophysiology of car-
diopulmonary dysfunction -Coronary circulation and effects of arterio-
graphic lesions on flow (human)
P0,HL-,5, 94-07 00,8 (HEPA) KLOCKE. FRANCIS J. Pathophysiology of car-
diopulmonary dysfunction-Coronary circulation, metabolic demand and
vasodilatory reserve (human, dogs)
P0,Hl-,5, 94-07 00,9 (HEPA) KLOCKE. FRANCIS J. Pathophysiology of car-
diopulmonary dysfunction-Coronary circulation, bypass grafts and
diastolic driving pressure (human, dogs)
P0,HL-,5,94-07 0020 (HEPA) GREENE, DAVID G. Pathophysiology of cardiopul-
monary dysfunction-Coronary circulation in arteriographically normal
arteries (human).
P0,Hl.|5194.07 0022 (HEPA) KLOCKE, ROBERT A. Pathophysiology of car-
diopulmonary dysfunction-Kinetics of gas exchange-Pulmonary carbon
dioxide exchange (dogs)
POIHl-, 5, 94-07 0023 (HEPA) KLOCKE, ROBERT A. Pathophysiology of car-
diopulmonary dysfunction-Distribution of ventilation-Diffusion and
cardiogenic agitation (dogs)
POJHL-, 5, 94-07 0024 (HEPA) SALTZMAN. ALAN R. Pathophysiology of car-
diopulmonary dysfunction-Distribution of ventilation-Airflow limitation
in COLD (human),
POIHL., 5, 94-07 0025 (HEPA) REICHLIN, MORRIS. Pathophysiology of cardiopul-
monary dysfunction-Myoglobinemia as an index of myocardial
ischemia and infarction
P0,HL-,5,94-07 9000 (HEPA) KLOCKE. FRANCIS J. Pathophysiology of car-
diopulmonary dysfunction -Animal laboratory core
P0,HL.I5, 94-07 900, (HEPA) KLOCKE. FRANCIS J. Pathophysiology of car-
^, diopulmonary dysfunction -Analytical laboratory core
POIHl.,5,94-07 9002 (HEPA) MATES, ROBERT E. Pathophysiology of cardiopul-
~..^. ., "'°""^ dysfunction -Data processing laboratory core
POlHL-,5,94-07 9003 (HEPA) MATES. ROBERT E. Pathophysiology of cardiopul-
monary dysfunction-Electronics laboratory core
P0IHl-I5,95-04 (HEP) WALTON. ALAN G. CASE WESTERN RESERVE UNIV 801
OLIN BUILDING. CLEVELAND. OHIO. Program project in biolog ca
materials.
P0,HL.,5, 95-04 000, (HEP) ANDERSON, JAMES M. Program project In biologi-
cal materials-Design and synthesis
P0,Hl.,5,95.04 0002 (HEP) WALrON, ALAN G. Program project In biological
materials-Structural and surface characterization.
544
PO,Hl
PO,HL
ROIHl
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ROIHL-
ROIHL
ROIHt
RO,HL
POIHL.
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PO,HL-
POIHL-
POIHL
POIHL.
PO,HL-
RO,HL-
RO,HL-
R01HL
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RO,Hl.
ROIHL-
RO,HL
ROIHL
ROIHL-
ROIHl.
ROIHL.
RO,HL-
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P50HL
P50HL
P50HL-
P50HL.
P50HL.
P50HL
P50HL-
P50HL-
P50HL.
P50HI.
-,5,95.04 0003 (HEP) HILTNER, PHYLLIS A. Program project in biological
materials -Mechanical evaluation and fabrication
-,5,95-04 0004 (HEP) CATANZARO, P. Program project in biological
materials-Biological evaluation and surface interaction studies
(dogs).
-15215-06 (HEM) DALMASSO. AGUSTIN P. VETERANS ADMIN HOSPITAL
54TH ST & 48TH AVE SO. MINNEAPOLIS. MINN. Role of complement iii
intravascular coagulation (rabbits, mice)
15226-06 (HEM) NIEWIAROWSKI. STEFAN. TEMPLE UNIVERSITY HEALTH
SCIENCES CENTER. PHILADELPHIA. PA. Interaction of blood cells with
fibrinogen and fibrin (human, animals)
15230-05 (HEM) HOUGIE. CECIL. UNIV OF CALIFORNIA, SAN DIEGO DE-
PARTMENT OF PATHOLOGY, LA JOLLA, CALIF. Molecular basis of V Wil-
lebrand s disease and hemophilia (human, cattle)
-15231.05 (CVA) CHOU. CHING-CHUNG. MICHIGAN STATE UNIVERSITY
DEPARTMENT OF PHYSIOLOGY, EAST UNSING, MICH. Mechanisms of
hemodynamic changes during digestion (dogs)
-.,5247-05 (SGYA) PARSONNET. VICTOR. BETH ISRAEL MEDICAL CENTER
201 LYONS AVENUE, NEWARK, N J. Extending the life of implanted
pacemakers (dogs, human).
-,5263-06 (MET) ALBERS. JOHN J. HARBORVIEW MEDICAL CENTER 325
9TH AVENUE, SEAHLE, WASH. Lecithin -Cholesterol acetyltransferase
(human, rabbits).
•15265-05 (HEP) BUCHWAID. HENRY. UNIVERSITY OF MINNESOTA HOSP
BOX 290 MAYO BLOG, MINNEAPOLIS, MINN. Program on surgical con:
trol of the hyperlipidemias
-15265.05 0003 (HEP) MOORE. RICHARD B. Program on surgical control
of the hyperlipidemias-Central lipid laboratory
-15265.05 0004 (HEP) LONG. JOHN M. Program on surgical control of
the hyperhpidemias-Coordinating center and central data processing
-,5265.05 001, (HEP) TUNA. NAIP. Program on surgical control of the
..o^. nyperlipidemias-Central electrocardiography laboratory (human)
■15265-05 00,2 (HEP) AMPLATZ,. Program on su'gical control of the hyper-
. =,x. „ J'P"'«""3S-Central arteriography-Radiography laboratory (human)
15265-05 0013 (HEP) MCMULLEN. JOHN. Program on surgical control of
the hyperlipidemias-Clinical center - Minnesota
,5265-05 0014 (HEP) CAMPBELL, GILBERT S. Program on surgical con-
trol of the hyperhpidemias-Arkansas clinical center
,5270-06 (CVB) VAISHNAV. RAMESH N. CATHOLIC UNIV OF AMERICA
SCH OF ENGR & ARCHITECTURE, WASHINGTON, 0 C. Local mechanicai
properties of the aortic tissue (dogs pigs)
,5273-06 (CVA) BALINT. JOHN A. DEPT OF MEDICINE, ALBANY MEDICAL
COLLEGE. ALBANY, N V. Metabolism of pulmonary surfactant (human
rats).
,5284.06 (BBCB) PARKHURST, LAWRENCE J, UNIVERSITY OF NEBRASKA
HAMILTON HALL 525, LINCOLN, NEBR. Hemoglobin and myoglobin
kinetic studies (human, animals) j b u" "
15293.07 (BBCB) FAIRCHILD BEATRICE M, ST LUKES HOSPITAL CENTER.
1I4TH STREET & AMSTERDAM AVE, NEW YORK, N Y Sickle cell
hemoglobin-Interactions and aggregation (human)
,5307-06 (CVB) ZEHR. JOHN E. UNIVERSITY OF ILLINOIS, 524 BURRILL
HALL URBANA, ILL. Central nervous control of renin and blood pres-
sure (dogs).
-,5308-07 (MET) SCHONFELD. GUSTAV. WASHINGTON UNIVERSITY. BOX
8046. 4566 scon AVENUE, ST LOUIS. MO. Assays for peptides of
lipoproteins (human).
■15316-07 (CVA) HITCHCOCK. KAREN R, TUFTS UNIVERSITY 136 HAR-
RISON AVENUE BOSTON, MASS. Lung surfactant s^ie.^ Control
mechanisms (rats).
■15335-06 (HEM) SIMONS. ELIZABETH R, BOSTON UNIVERSITY 80 EAST
CONCORD STREET, BOSTON, MASS. The nature of the co I gen pla elet
interaction (animals). piaieiei
15341-06 (HED) CHYTIL, FRANK. VANDERBILT UNIVERSITY SCHOOL OF
'"'^■"cHfrA"r''n ,"A«^"' .-""^MIAH. 303 EAST CHICAGO AVENUE,
CHICAGO, ILL. Cooperative study of drugs and coronary heart disease
(human).
15376.06 (PC) SCHROEPFER, GEORGE J. JR. RICE UNIVERSITY DEPT OF
BI()CHEMISTRY, HOUSTON, TEX. Intermediary metabohsm of sterol
,5378-06 (BBCA)DETITTA GEORGE T, MED END OF BUFFALO. INC, 73
TtagS. ''"''°' ' ' "'"'''"'''"' 0' antihypertensive
,5389-07 (SRC) FINK. JORDAN N. MEDICAL COLLEGE OF WISCONSIN 561
le^r^r'' "'^^*"^^^' ^'^- ""'""--^ SColZerselvi,;
-15389-07 0001 (SRC) EMANUEL, DEAN A. Pulmonary SCOR-Hypersen-
iS3«o „J'^:;;l''";"'"'"'i'i5--Clinical studies of hypersensitivity pneumonitis
■15389.07 0008 (SRC) SCHLUETER, DONALD P. Pulmonary SCOR H per-
pneumomtis. P"^"'"°"*^-'^''««"^^^ Patient study-Hypersensitivt;
.15389.07 0009 (SRC) EMANUEL. DEAN A. Pulmonary SCOR-Hypersen-
15389 07 omoTorf-'^''"'"' ^"""«--P''""onary mycotoxicosis.
■15389-07 00,0 (SRC) PATTERSON. ROY. Pulmonary SCOR-Hypersensitivi-
Isperglsis ^'""y-Pul^onary lesions due to non-invasive
15389.07 00,, (SRC) MOORE, VERNON I. Pulmonary SCOR-Hypersen-
raSs. ""^'""P"*'-*"™^' model-Hypersensitivity pneumonms in
■15389-07 00,2 (SRC) MOORE, VERNON L. Pulmonary SCOR-Hypersen-
gu,'nea^,'i^""'""''"■*"™" '"'"'"■•''"^""''l»8ic lung disease in
,5389-07 00,3 (SRC) MARX. JAMES J. Pulmonary SCOR-Hypersensitlvity
pn^eumonitis-Animal model-Pulmonary mycotoxicosis (rabbit, guinea
,5389.07 00,4 (SRC) FREDRICKS. WALTER W. Pulmonary SCOR-Hyper-
sensitivity pneumonitis-Fractionation and characterization of pigeon
antigens. Kisouii
15389.07 00,5 (SRC) ROBERTS. RONALD C. Pulmonary SCCR-Hypersen-
sitivity pneumonitis-Fractionation and characterization of thermophilic
Actinomycete antigens.
15389-07 00,6 (SRC) SCHLUETER. DONALD P. Pulmonary SCOR-Hyper-
sensitivity pneumonitis-Pulmonary physiology core (human)
MOHL
PSOHl
MOHl-
PSOHl-
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ROIHL
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ROIHL-
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POIHl-
POIHI-
ROIHl-
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ROIHL
R01HL-
R01HL
S4S
)S3l9-07 00«7 (SRC) BARSORIAK, JOSiPH J. Pulmoniry SCOR Hyper
sensitivity pneumonitis Immunolojy coie (human)
1S3I9-07 00«8 (SRC) OARANCIS, JOHN. Pulmonary SCOR Hypetsen
sitiwity pneumonitis Patholoty core (liuman. animal)
1S3t9-07 0019 (SRC) KURUP, VISWANATH P. Pulmonary SCOR Hyper
sensitivity pneumonitis Microbiology core (human, animal)
15389-07 OOaO (SRC) RIMM, ALFRED A. Pulmonary SCOR Hypersensitivity
pneumonitis Computer applications and data analysis core,
.15390-12 (PHY) JOHNSON, PAUL C, ARIZONA HEALTH SCIENCES CENTER.
PHYSIOLOGY DEPARIMENl. TUCSON. ARIZ Rejulation ol blood llow in
the microcirculation
.15391-07 (BBCB) SEIDEL, JOHN C, 20 STANIFORD STREET, BOSTON. MASS
EPR studies on rotational motion of myosin and actin
-15392-06 (PHRA) PRICE. HENRY I, HAHNEMANN MEO COLLEGE & HOSP.
235 NORTH FIFTEENTH STREET. PHILADELPHIA. PA Autonomic and cir
culatory actions ol anesthetics (dog. cat. rabbit, monkey)
-15416-06 (CVA) VATNER, STEPHEN P, PETER BENT BRIGHAM HOSPITAL,
721 HUNTINGTON AVENUE. BOSTON. MASS. Cardiovascular control in
normal and disease states (dogs, baboons).
15427-06 (MET) SCHONPELO, GUSTAV. WASHINGTON UNIVERSITY. BOX
8046. 4566 SCOH AVENUE. ST LOUIS. MO Secretion ol plasma
lipoproteins (rats)
15430-05 (CVB) COTTON, ERNEST K, UNIVERSITY OF COLORADO. 4200
EAST NINTH AVENUE. DENVER, COLO Cardiopulmonam adaptation of
newborns to altitude (human)
.15444-06 (CVA) BUCKLEY, NANCY M, ALBERT EINSTEIN COLL OF MED,
1300 MORRIS PARK AVENUE. NEW YORK, N Y. Neonatal development
of adrenergic receptor mechanisms (pigs).
15447-06 (PHRA) DUNHAM, EARL W, UNIVERSITY OF MINNESOTA. 105
MILLARD HALL. MINNEAPOLIS. MINN. Vascular role of prostaglandin
and cyclic nucleotides (rats),
.15448-06 (SGYB) HAGEN, PER-OTTO F, DUKE UNIVERSITY, DEPARTMENT
OF SURGERY, DURHAM, N C Surgical and metabolic aspects of
venous grafts, (dogs, monkeys, rabbits).
-15460-06 (BBCB) BONAVENTURA, JOSEPH, DUKE UNIVERSITY. MARINE
LABORATORY. BEAUFORT. N C. Molecular adaptation-Hemoglobin
systems of fish (marine),
.15469-06 (AFY) DEMPSEY, JEROME A, 504 NORTH WALNUT STREET.
MADISON WIS Human ventilatory adaptation (also, dogs, rats).
15474-06 (HEM) KIRBY, EDWARD P, TEMPLE UNIVERSITY. DEPARTMENT OF
BIOCHEMISTRY, PHILADELPHIA, PA. Structure and function of the an-
tihemophilic factor (human, cattle).
15476-05 (BIO) ORITZ DE MONTELLANO, PAUL, UNIVERSITY OF
CALIFORNIA. 926 MEDICAL SCIENCES BUILDING , SAN FRANCISCO,
CALIF Mechanism and control of sterol biosynthesis (rats),
.15478-05 (NTN) LANGNER, RONALD O, UNIVERSITY OF CONNECTICUT,
SCHOOL OF PHARMACY, STORRS, CONN. Lipid flux and collagen
synthesis in atherosclerosis (rabbits),
.15486-06 (HEPB) NOSSEL, HYMIE L, COLUMBIA UNIVERSITY, 630 WEST
168TH STREET, NEW YORK, N Y. Studies on thrombosis.
15486-06 0001 (HEPB) CANFIEID, ROBERT E. Studies on thrombosis-
Studies on chemistry of fibrinogen (human, dogs).
■ 15486-06 0002 (HEPB) BUTLER, VINCENT P. Studies on thrombosis -
Characterization of antisera to fibrinopeptide B (human, rabbits).
■ 15486-06 0003 (HEPB) NOSSEL, HYMIE L. Studies on thrombosis -
Mechanism and prevention of fibrinopeptide B degradation (human).
■ 15486-06 0004 (HEPB) WILNER, GEORGE D. Studies on thrombosis -
Thrombosis, intravascualr coagulation, platelet aggregation (dogs).
15486-06 0005 (HEPB) KAPLAN, KAREN L. Studies on thrombosis -Isola-
tion and characterization of PF4 antigens (rabbits).
15486-06 0006 (HEPB) NOSSEL, HYMIE L. Studies on thrombosis -Clinical
investigation unit.
■ 15491-06 (HEM) ZIMMERMAN, THEODORE S, SCRIPPS CLINIC &
RESEARCH FDN, 10666 NORTH TORREY PINES ROAD , LA JOLLA, CALIF.
Blood coagulation-Platelet-plasma protein interaction (human).
-15498-06 (CVB) SCHEUER, JAMES, MONTEFIORE HOSP & MEDICAL CTR,
111 EAST 210TH STREET, BRONX, N Y. Effects of physical training on
heart (rats).
15504-05 (NTN) KUMMEROW, FRED A, HARUN E MOORE HEART RES
FDN, 805 SOUTH OAK STREET, CHAMPAIGN, ILL. Animal model for stu-
dies on averting atherosclerosis (sv»ine).
.15512-06 (CVB) KRAMSCH, DIETER M, UNIVERSITY HOSPITAL. 75 EAST
NEWTON STREET, BOSTON, MASS, Drug treatment of stenosing primate
atherosclerosis (rabbits, monkeys).
15520-06 (SGYA) GEYER, ROBERT P, HARVARD SCHOOL OF PUBLIC HLTH,
665 HUNTINGTON AVENUE, BOSTON, MASS. Total blood replacement by
fluorocarbons and polyols (rats).
15522-06 (CVB) WILLERSON, JAMES T, UNIVERSITY OF TEXAS, 5323
HARRY HINES BOULEVARD, DALLAS, TEX. Influence of mannitol on
ischemia cardiac muscle (dogs, cats, rats).
15526-05 (CVA) WOHL, MARY E, 300 LONGWOOD AVE, CHILDREN'S
HOSPITAL MED CTR, BOSTON, MASS. Respiratory mechanics in chil-
dren.
15528-05 (CVB) KOTCHEN, THEODORE A, UNIVERSITY OF KENTUCKY,
DEPARTMENT OF MEDICINE, LEXINGTON, KY. Renin kinetics in hyper-
tensive and uremic plasma (human, dogs).
15535-06 (BIO) LAURSEN, RICHARD A, BOSTON UNIVERSITY. 685 COM-
MONWEALTH AVENUE. BOSTON, MASS. Structure and function of
human plasmin.
15562-05 (CVB) SKINNER, NEWMAN S, JR. BOWMAN GRAY SCHOOL OF
MEDICINE. DEPT OF PHYSIOLOGY, WINSTON-SALEM. N C, Regulation of
skeletal muscle blood flow (dogs).
15567-05 (MET) HUGGINS, CLYDE G, UNIVERSITY OF SOUTH ALABAMA,
DEPARTMENT OF BIOCHEMISTRY. MOBILE, ALA. Cardiovascular
phosphoinositide metabolism (rats).
15580-06 (CVA) KADOWITZ, PHILIP J, TULANE UNIVERSITY. 1430 TUUNE
AVENUE, NEW ORLEANS, LA. Humoral control of pulmonary and
systemic circulation (animals).
15593-05 (SGYA) BARTIETT, ROBERT H, UNIVERSITY OF CALIFORNIA. DE-
PARTMENT OF SURGERY, IRVINE, CALIF. Prolonged extracorporeal car-
diopulmonary support (rats, sheep, rabbits).
15596-05 (HEP) JOHNSON, ALAN J, NEW YORK UNIVERSITY. 550 FIRST
AVENUE. NEW YORK. N Y. Coagulation, fibrinolysis, hemostasis and
hepatitis.
ROIHL
ROIHL-
ROIHL
ROIHL-
ROIHI
ROIHL
ROIHI-
POIHI
POIHl-
POIHL-
P01HL
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15596
15596
■ 15596
P01HL-1SS96
POIHI
POIHL
15596
15596
P01HL-15596
POIHL- 15596
POIHL
P01HL-
POIHL-
POIHL.
ROIHL
15596
15596
-15596.
15596
■ 15607
R01HI-156M
ROIHL
ROIHL
15615
15616
ROIHL-15619^
R01HL-1S622
ROlHL-15627
R01HL-15640
R01HL-1 5646-1
R01HL-15647
ROlHl-15648
R01HL-15655
R01HL-156S9
R01HL-1S668
R01HL-15676
R01HL-15677
ROIHL- 15679
R01HL-15681
R01HL-15685
R01HL-1S690^
R01HL-15692
R01HL-15694
R01HL-1S696
R01HL-1S698
PROJECT NUMBER AND INVESTIGATOR ADDRESS
OS 0001 (HEP) MERSKIY, CLARINCI. Coi|ulilion. Ilbrlnolytii.
hemostasis and hepatitis Delibrination (human)
■05 0002 (HiP) NOSSEL, HYMII, Coagulation, (ibrinolysn, hemoila
SIS and hepatitis Radioimmunoassay ol fibrinogen and fibrin derlv*
lives (human) . . , ,. ■
-05 0003 (HEP) MOSESSON, MICHAEL W. Coagulation. Iibrinoly
SIS. hemostasis and hepatitis Plasmin degraded librinogen Iradioni
(human)
-OS 0007 (HEP) ONO, ENO B. Coagulation, fibrinolysis, hemostaju
and hepatitis Structural studies and fractionation of urokinau
(human)
■OS 0008 (HEP) NEWMAN, JACK. Coagulation. Iibnnolysu. nemos
tasis and hepatitis Structural studies and fractionation of antihemo-
philic factor (human)
-OS 0010 (HEP) JOHNSON, ALAN J. Coagulation, fibrinolysis.
hemostasis and hepatitis Von Willebrands factor (human)
-OS 0012 (HEP) ZUCKER, MARJORIE B. Coagulation, fibrinolysis,
hemostasis and hepatitis Platelet function Phorbol ester and
zymosan induced release activity
05 0014 (HEP) FINLAY, THOMAS H. Coagulation, fibrinolysis,
hemostasis and hepatitis Von Willebrand factor and platelet retention
in glass bead columns (swine)
.05 0016 (HEP) JOHNSON, ALAN J. Coagulation, fibrinolysis,
hemostasis and hepatitis HepatitisB antigen in whole blood, plasma
and plasma fractions (human, monkeys)
-05 0017 (HEP) FINLAY, THOMAS H. Coagulation, fibrinolysis.
hemostasis and hepatitis- Heparin and antithrombin III.
-05 0018 (HEP) MERSKEY, CLARENCE. Coagulation, fibrinolysis,
hemostasis and hepatitis-Increased plasma lipids on blood coagula-
tion and thrombosis (human, animals),
-05 0019 (HEP) ONG, ENG B. Coagulation, fibrinolysis, hemostasis
and hepatitis-Protamine assay and serine proteases,
05 0020 (HEP) HODGINS, LEONARD T. Coagulation, fibrinolysis.
hemostasis and hepatitis -Affinity chromatography.
-06 (CVB) HIRSCH, LEROY J, MICHAEL REESE HOSP & MED CTR.
29TH STREET & ELLIS AVENUE, CHICAGO, ILL 60616, Physiological
control of splanchnic circulation (dogs).
.04 (EDC) SCHULL, WILLIAM J, UNIVERSITY Of TEXAS, 6901
BERTNER AVENUE, HOUSTON, TEX. Heredity and oxygen -Effects on
health of heart-lungs (South America)
■06 (HEM) MC KEE, PATRICK A, DUKE UNIVERSITY. BOX 3705, DUR-
HAM N C Structure-function studies of human factor VIII/vWF.
-04 (HEM) PHILLIPS, DAVID R, ST lUDE CHILORENS RES HOSP,
POST OFFICE BOX 318, MEMPHIS, TENN. Platelet membrane proteins
in aggregation (human).
-05 (HEM) MUNNS, THEODORE W, ST LOUIS UNIVERSITY, 1402
SOUTH GRAND BLVD, ST LOUIS, MO Regulation of prothrombin synthe-
sis in cultured cells (rats).
.05 (COM) GARFINKEL, DAVID, UNIVERSITY OF PENNSYLVANIA.
MOORE SCH OF ELECTRICAL ENGR. PHILADELPHIA, PA. Computer simu-
lation in cardiology (rats. dogs).
■06 (BBCB) SCHEIDT, W ROBERT, UNIVERSITY OF NOTRE DAME. DE-
PARTMENT OF CHEMISTRY. NOTRE DAME. IND. X-ray and chemical stu-
dies of metalloporphyrins.
-06 (MCHB) CUMMINGS, SUE C, WRIGHT STATE UNIVERSITY, DE-
PARTMENT OF CHEMISTRY, DAYTON, OHIO. Thermodynamic studies on
model oxygen carriers.
■03 (MET) GEYER, ROBERT P, HARVARD SCHOOL OF PUBLIC HLTH.
665 HUNTINGTON AVENUE. BOSTON, MASS. Lipid studies in vascular
smooth muscle cells (human, monkeys).
-06 (HEM) JONES, JIMMY B, UNIVERSITY OF TENNESSEE. 1924
ALCOA HIGHWAY, KNOXVILLE. TENN. Hematopoietic studies of cyclic
hematopoiesis (dogs).
-06 (BBCB) SMITH, LOUIS C, BAYLOR COLLEGE OF MEDICINE. 1200
MOURSUND AVENUE. HOUSTON, TEX. Lipid metabolism-Transport by
lateral diffusion (human, rabbit, cattle).
-OS (HED) POWER, GORDON G, LOMA LINDA UNIVERSITY, SCHOOL
OF MEDICINE, LOMA LINDA, CALIF. Blood flow and gas exchange in
placenta and lungs (sheep) rabbits).
.05 (CVA) BELLVILLE, J WELDON, UNIVERSITY OF CALIFORNIA, DE-
PARTMENT OF ANESTHESIOLOGY. LOS ANGELES. CALIF. Dynamic isola-
tion studies of control of respiration (human).
■06 (SGYB) UPDIKE, STUART J, UNIVERSITY HOSPITALS. 1300
UNIVERSITY AVENUE, MADISON, WIS. Extracorporeal respiratory gas
exchange-A new approach (dogs).
-06 (SGYA) SIEGEL, JOHN H, BUFFALO GENERAL HOSPITAL. 100
HIGH STREET, BUFFALO. N Y. The role of occult myocardial failure in
human shock (human, dogs).
06 (CVA) MATHE, ALEKSANDER A, BOSTON UNIVERSITY, 80 EAST
CONCORD STREET, BOSTON, MASS. Autonomic nervous system func-
tion in bronchial asthma (human, guinea pig, rabbit).
■06 (BBCB) ROBSON, RICHARD M, IOWA STATE UNIVERSITY,
MUSCLE BIOLOGY GROUP, AMES, IOWA. Heart and smooth muscle con-
tractile protein (swine, cattle, rabbits, chickens).
■06 (CVA) FOLTS, JOHN D, CARDIOVASCULAR RES LABORATORY,
420 N CHARTER STREET, RM 523, MADISON, WIS. Coronary flow stu-
dies of partially obstructed vessels (dogs).
-05 (HEM) CRONKITE, EUGENE P, BROOKHAVEN NATIONAL LABORA-
TORY. MEDICAL DEPARTMENT. UPTON. N Y. Hemopoietic regulators
produced in cell culture (human, animals).
.07 (HEM) DONALDSON, VIRGINIA H, CHILDREN'S HOSPITAL RES
FDN, ELLAND & BETHESDA AVENUES. CINCINNATI. OHIO. Hydrolytic en-
zymes of blood in health and disease (human, animals).
■07 (PHY) WEBER, ANNEMARIE A, UNIVERSITY OF PENNSYLVANIA.
DEPARTMENT OF BIOCHEMISTRY. G3. PHILADELPHIA. PA. Force and
speed in skeletal and cardiac muscle.
-06 (CVA) LLOYD, THOMAS C, JR, INDIANA UNIVERSITY. 1100 W
MICHIGAN STREET. INDIANAPOLIS, IND. Pulmonary factors in circulato-
ry regulation.
-06 (PHRA) KUO, JYH-FA, EMORY UNIVERSITY. DEPARTMENT OF
PHARMACOLOGY, ATLANTA, GA. Mechanism and role of cyclic GMP in
heart (animals).
-12 (PHRA) WOSILAIT, WALTER D, UNIVERSITY OF MISSOURI. DE-
PARTMENT OF PHARMACOLOGY. COLUMBIA. MO. Factors affecting the
action of anticoagulants (rats, human).
mi^
PROJECT NUMBER AND INVESTIGATOR ADDRESS
ROlHl-l 5722-06 (CVB) MEISEIMAN, HERBERT J, UNIV OF SOUTHERN CAIIFnR
>Aiu. ..,- '^*"' '° '" """' '''''<'<* 'liw (human).
ROlHl-1 5728-06 (HEM) NELSESTUEN. GARY I. UNIVERSITY OF MINNESOTA 140
>n.u. .<, "loof-clotting glycoproteins (mammals). J die oi me
«0I Hl-l 5740-06 (CVA) BERNS, MICHAEl W, UNIVERSITY OF CALIFORNIA
R0,Hl-,5758-06 j^CVB, lEVY MAnHEW N, MT SINAI HOSPITAL, 1800 E 105
ROIHl 1 5764 OS rrll\^,»^ ■ ""'^ Catecholamine release in the heart (dogs)
ROIHI-1 5764-05 (CVA) KIRCHBERGER, MADELEINE A. MOUNT SINAI HOSPITAL
mn AVENUE & lOOTH STREET. NEW YORK N Y. C AMP dependeni
""""" '""'" '" """'=<: contraction (dogs) Dependent
«0IHl-,5781-06 (RAO) H.LAI SADEK K. NEUROLOGICAL INSTITUTE, 710 W 168TH
Sh^u^anT '■ ' ' '"""' """'^' "''''''""' "' '"' --"'-
ROlHl-1 5790-06 (EDO MOSS. ARTHUR J. UNIVERSITY OF ROCHESTER 601 ELM
r aSL^^nf™' ' ' ^""-- --^ °' -"'^ --
ROlHl-15793.06 (HEM) JOHNSON, ROBERT M, WAYNE STATE UNIVERSITY 540
i^^.x:.r """" -"'^ °' '^Se'm^r
R0IHI.1S797.05 (PTHA) HAYES. KENNETH C, HARVARD SCHOOL OF PUBLIC
HL H. 665 HUNTINGTON AVENUE, BOSTON, MASS. Lipid metabolism
R0.H.,57„.04 "(S^pS HeZ;*!! rSANrME; cZT'hOSP .5
.l^n Sts)."'"^^^^"'*' '' ^"-* "' --'^^"" - ---'a^
ROI Hl.1 5805.06 (PHRA) BEVAN, JOHN A, UNIVERSITY OF CALIFORNIA DEPT OF
rS^Ss).^"^ ''"''''■ "- '^-^'^' -.' ■tonfa^d^
ROlHl.15808-06 (CVB) PRINTZ. MORTON P. UNIV OF CALIF SAN DIEGO DEPART
MENT OF MEDICINE, U JOLL., CALIF. Role ofangio te inogen .^^
hypertension and stroke (human, rabbits)
R01HI.I58I0-06 (CVB) COHEN, JORDAN J, NEW ENGi;»NO MEDICAL CTR HOSP
71 HARRISON AVENUE, BOSTON, MASS. Electrolyte phsoLgy and
respiratoiv acidbase (dogs)
R01HI-1S813-05 (SGYA) HEWITT, ROBERT L, TUUNE UNIVERSITY 143C TUUNE
SLZr'"' " '"'"' -»--o'ect,ve eZ^a^r^
ROtHl-15817-06 (HEM) COIE, EDMOND R. RUSHPRESBYST LUKES MED CTR
,luZ'l '°'T' '*'"^*'' '"'''''■ '^^- Pla-'nogen ac /v :
tors from tissues (human, pig, cattle)
P01HI-15832-06(HIBB) TURING, GERARD M, COLUMBIA UNIVERSITY, 630 WEST
lung inj^r '*""• ' '■ ''''"'"''■'""''""> Predispositiors to
POl HI-. 5832-06 0001 (HIBB) MANDl. INES. Chemical-structural predispositions
nrnt.in". rh'"""^""'?' """Position of lung connective tissue
proteins (human, animals)
PO.Hl-15832-06 0002 (HIBB) GODMAN, GABRIEL C. Chemical-structural
predispositions to lung injury-Connective tissue in lung in develop-
ment and repair of injury (human, rats, mice)
POl HL-1 5832-06 0004 (HLBB) TOR.O, GERALD M. Chemical-Structural
predispositions to lung injury-Proteolytic activity leucocytes in pa-
tients with obstructive lung disease
POlHl-,5832-06 0005 (HLBB) SKALAK. RICHARD. Chemical-structural
Srh^sTral:)'""' '"'"'^■■'•"'"'»-'V ^'-'-e and stress-strain
POl HL-l 5832-06 0007 (HLBB) GREENBAUM. LOV.ELL M. Chemical-structural
predispositions to lung injury-lnactivation of vasoactive agents by the
lung (human, rats, cats, dogs)
P01HL-.5832-06 0008 (HLBB) MANDL. INES. Chemical-Structural predispositions
nnrlTJn? "1";"" '''""'^-^"''ective tissue components in
normal and diseased lungs
POl HL-1 5832-06 0009 (HLBB) MANDL. INES. Chemical-structural predispositions
to lung iniury-jmmunology-Enzyme degradation products of human
lung elastin and microfibril
P01HL-.5832-06 0010 (HLBB) GREENBAUM. LOWELL M. Chemical-structural
predispositions to lung injury-Kinin generating systems In pulmonary
disease (human, animals)
PO.HL.15832-06 00.1 (HLBB) HEINEMAN, HENRY O. Chemical-structural
predispositions to lung injury-Interaction of cell receptors v»ith
vasoactive agents in pulmonary vascular bed
POIHL.15832.06 0012 (HLBB) GODMAN. GABRIEL C. Chemical-structural
predispositions to lung injuiy-Contractile structures and contractility
in cells of lung respiratory tract
POIHL.15832.06 9001 (HLBB) PARSHLEY. MARY S. Chemical-structural
predispositions to lung injury-Tissue culture studies of lung cell tunc-
i)on--Core facilrty
POlHL.15835-06 (HLBA) SOMLYO. ANDREW P, 51 NORTH 39TH STREET
P0.Ht-.5e35-06 000. HLBA) WEBER, ANNEMARiE. Study of muscles related
frabbfts, chickens?""'™' °' """^^"°"-^='^«^''''" <>' ^^art and muscle
PO.Hl-15835-06 0002 (HLBA) IYENGAR, M RAJA. Study of muscles related to
PO.HL i««^« nx tflJ'f"" ™"'"' °* '"'°°"' "'"'<='« ^'^'S"" '"«le. rabbits).
P0.Hl-.S835.06 0004 (HLBA) NACHMIAS, VIVIANNE T. Study of muscles re-
molds hum'an) '''"^''■■*'""">'"'" ^y^'e-^^ and cell motility (slime
P0,Hl..5835-06 0006 "(HLBA) PEPE. FRANK A. Study of muscles related to
heart disease -Ultrastructural and chemical studies of muscle
(animals).
P0.HL-.5835.06 0007 (HLBA) LEVINE. RHEA J C. Study of muscles related to
mu^scle ""''"'' ^"'' ''""^"°" °' '"''""'"^ ^'"^'"* '"■* """'ac
P0.HL-. 5835-06 0009 (HLBA) HOLT2ER. HOWARD. Study of muscles related to
heart disease -Aspects of cardiac and skeletal myogenesis (chick emb-
P0.H1..5835.06 00.0 (HLBA) KELLY. ALAN M. Study of muscles related to
PO.Hi i$«^« nx !,'r.,"!'"^ "'' """^"'^ '"" 'taction to injury (mice, rats)
PO.Hl-,5835-06 00., (HLBA) DAVIES. ROBERT E. Study of muscles related to
(frogs. SsT ""*'''" '"" "''*''"'"" "' -"""'« contraction
546
PO.HL-1
POl HI
P01HL
PO.HL-
PO.HL..
PO.HL
PO.HL-
PO.HL.
RO.HL-
ROIHI-
ROIHL
RO.HL-
RO.HL-
RO.HL-
RO.HL
RO.HL
RO.HL-
RO.HL-
RO.HL
RO.HL.
RO.HL-
R01HL-
RO.HL
RO.HL-
RO.HL
P60HL-
P60HL.
P60HL
P60HL.
P60HL-
P60HL.
P60HL
P60HL-
P60HL-
P60HL-
P60HL
P60HL-
P60HL-
.5835-06 00.2 (HLBA) SIEGMAN, MARION J. Study of muscles related
to heart disease -Contraction and energetics of visceral and vascular
smooth muscles (rabbits).
•15835-06 00.3 (HLBA) CHANCE. BRITTON. Study of muscles related to
heart disease-Cardiac bioenergetics (rats)
15835.06 0018 (HLBA) BIANCHI. C PAUL. Study of muscles related to
heart disease-Pharmacology of excitation coupling in muscle (frog
barnacles). "
.5835-06 0019 (HLBA) SOMLYO, ANDREW P. Study of muscles related
0 heart disease-Vascular smooth muscle-Electron microscopy, excita-
tion contraction (animal).
15835-06 002. (HLBA) SCARPA, ANTONIO. Study of muscles related to
heart disease-Fast kinetic studies in muscle subcellular organelles
..5835-06 0023 (HLBA) W.NEGRAD, SAUL. Study of muscles related to
.5835 o* o^i"!!.? ! "'" "'''' °* '"' frank-Starling curve (frogs, rats).
.5835-06 0025 (HLBA) CHACKO, SAMUEL. Study of muscles related to
heart disease-Cellular biology of vascular smooth muscle (guinea
-.5835.06 0027 (HLBA) PEPE, PRANK A. Study of muscles related to
heart disease-Core II -Intermediate voltage EM of muscle
.15837-06 (CVB) TARAZI, ROBERT C, CLEVELAND CLINIC FOUNDATION
frnl'"?".*''""''/'"^"""' O"'" "'"'" and cardiac hyper:
trophy in hypertension (rats)
.15839-05 (CVB) CARRETERO. OSCAR A, HENRY FORD HOSPITAL. 2799
WEST GRAND BOULEVARD, DETROIT, MICH. Physiological role of
isorenin and kallikrein (animals)
15840-02 (NTN) NAKAMURA, ROBERT M, DEPT OF ANIMAL SCIENCES
UNIVERSITY OF HAWAII, HONOLULU. HAWAII. Sugar-induced heart ,1:
,co<, „x ,"i.' """"'" •* ''«''C'ency (birds, mammals subhuman)
.5852-06 (CVB) JONES. ALLAN W. UNIVERSITY OF MISSOURI M-412
MEDICAL SCIENCES BLDG, COLUMBIA, MO. Vascular ion transport a
hypertensive mechanisms
.5887-05 (HEM) LAWSON. WIUIAM B. NEW YORK STATE DEPT OF
1.^ • hTk'"^ ?"'^ ''^^*' *^«*"'' " ^- E"^-"" <>< "lood coagu-
lation and fibrinolysis (human).
.5888-05 (CVA) BOSSEN, EDWARD H, DUKE UNIVERSITY DEPARTMENT
OF PATHOLOGY, DURffAM. N C. Comparative stereoloVoMhe* mylar
dium (birds, mammals)
■'"'^""sTmlrT fif.'pfTcTl'rr**'^"*"' "• "OS^ELL PARK MEM IN-
(hlL . «, ^^" ^{"^fT, BUFFALO, N Y. Inhibitors of proteinases
(human, cattle, swine)
■'""■°«eTuI' BS°Mis'.7 ^'^"^''f N'S HOSPITAL, 300 LONGWOOD
AVENUE, BOSTON, MASS. In vitro study of lipoproteins in vascular dis-
ease (human, animals).
.5930-06 (MET) MARGOUS, SIMEON, JOHNS HOPKINS SCHOOL OF MED,
innn , ^M^"^^!' ^^LTIMORE, MD. Hormonal control of lipid and
lipoprotein synthesis (rats).
-.5949-05 (MET) BILHEIMER, DAVID W, UNIVERSITY OF TEXAS 53?^
HARRY HINES BOULEVARD, OALt;*S, TEX. Lipoprotein me llism
relation to atherosclerosis (human, baboons)
.5958-06 (BBCB) TSERNOGLOU, DEMETRIUS, 540 EAST CANFIFI n
.5965-06 (PTHA) RUCKER, ROBERT B, UNIVERSITY OF CALIFORNIA DE-
a dlT °f r;!"™N' "AVIS. CALIF. Experimental herosleross
and elastin metabolism (chicks)
-15979-05 (PC) BAUMSTARK, JOHN S, CREIGHTON UNIVERSITY lOTH &
val f T"'' °"*"'' """• E'=^'^"' """" inhibitors d the
vasculature (human, swine)
15980-06 (BBCB) CAUGHEY, WINSLOW S, COLORADO STATE UNIVFRSI
TJ, DEPARTMENT OF BIOCHEMISTRY, FORT COLUNS COLO Re c ion
of hemeproteins and oxygen (cattle) neactions
.5983-04 (CVB) YIPINTSOI, TADA, MONTEFIORE HOSP & MEDICAL CTR
m EAST 210TH STREET, BRONX, N Y. Regional myocardial blood flow
.5985-06 (PHRA) BROOKER, GARY, UNIVERSITY OF VIRGINIA DEPART
m nil cl 'TT'T'' CHARLOHESVILLE, VA. Meta o c and ho !
monal control of cardiac contraction
-.5991-05 (PHRA) NORTON, TED R, UNIVERSITY OF HAWAII 3675 KIIAIIFA
aSnes""""'"'"' "'"'"■ ^^^'"^"o" ■>' heaTstimulantsTs"
15996-06 (SRC) LAMPKIN, BEATRICE C, CHILDREN'S HOSP RES FDN Fl
rsi?kre^:!f^cr ""^' '='"'='"-^'' -- -"^'iTehii;
.5996-06 000. (SRC) GRUPPO, RALPH A. Cincinnati comprehensive
(humanr ""*"--^°^^"'^''''" -"-danisms in sickle celltsea"
..5996-06 0003 (SRC) LAMPKIN. BEATRICE. Cincinnati comprehensive
:nemia"i'u:a:r™^'^'"'^ "'"'' ''«^*-"' °' '^^^'^ «N
■15996-06 0004 (SRC) HUFFMAN. ANN. Cincinnati comprehensive sickle
,«o. „."" """'-S^'^PCI adjustment of sickle cell patients
.5996-06 0005 (SRC) CHRISTIAN. EMILY. Cincinnati comprehensive
1599* o* „^«"' ""''^-factors precipitating crises (human). "'""""'""""
"° «°rEdSn'°'' ^""" '"'"-'" ^°""''«^-^- -^'^ cell
•15996-06 0007 (SRC) LAMPKIN, BEATRICE. Cincinnati comprehensive
sickle cell center-Screening and counseling comprenensive
• 15996-06 0008 (SRC) LAMPKIN, BEATRICE. Cincinnati comprehensive
sickle cell center-Patient care (children, adults)
.5996-06 0009 (SRC) LAMPKIN, BEATRICE. Cincinnati comprehensive
and disease" '"""'"" '°'""'' °' """"' """ ^'cTe ceTt'art
.5996-06 00.0 (SRC) GRUPPO, RALPH A. Cincinnati comprehensive
•15999 OS^mEP^B Z'::T.t *""" "'"""* '" ^'^^" "" anemia (hum )'
•15999-05 (HEPB) HARKNESS, DONALD R, UNIVERSITY OF MIAMI SCH OF
prehensive sickle cell center
'"""°'crr, (HEPB) DAVIES, JOHN E. Miami comprehensive sickle
cell center-Education, screening and counseling
15999-05 0005 (HEPB) HARKNESS, DONALD R. Miami comprehensive
sickle cell center -Sickle cell clinic.
547
PROJECT NUMBER AND INVESTIGATOR ADDRESS
P«0Hl-)S999-0S OOOa (HIPt) RATZAN, KINNITH R. Miami comprihenslv*
sickle call centei Cyanate eKect on hojt defense Cellulai and hu
moial (human, (uinea pit. labbilsl
P60HL-1S999-0S 0014 (HfPB) CAMERON, BRUCE F. Miami comprehensive
sickle cell centei Biochemical and moiphological paiameteis ol sickle
cells (human)
P60HI- 15999-05 0019 (HEPS) ZUCKER, ROBERT M. Miami compiehensive sickle
cell centei Fetal adult hemoglobin switch (mouse, monkey)
P60HI- 15999-05 0030 (HEPB) SCHUITZ, DUANE R. Miami compiehensive sickle
cell centei Deticiency in complement dependent humoral immunity
Sickle cell disease (human)
P60HI- 15999-05 0021 (HEPB) HARKNESS, DONALD R. Miami comprehensive
sickle cell center Diphosphonates- Erythrocyte calcium loading, matu-
ration (human, chick embryo)
ROIHl-16003-08 (PHRA) TRIGOIE, DAVID J, S U N Y AT BUFFALO, 224 CARY
HALL, BUFFALO, N Y Sources and roles ol calcium in smooth muscle
excitation (lats)
P60HI-1 6005-05 (SRC) BOWMAN, JAMES E, UNIVERSITY OF CHICAGO. 950 EAST
59TH STREET, CHICAGO, ILL Comprehensive sickle cell center
P60HL-16005-05 0001 (SRC) WARREN, SHIRLEY. Comprehensive sickle cell
center Demonstration-Community service component
P60HL-1 6005-05 0013 (SRC) GOLDWASSER, EUGENE. Comprehensive sickle
cell center Study of regulation of erythropoiesis in vitro (human, rat,
hamster, rabbit).
P60HL- 16005-05 0015 (SRC) SIGLER, PAUL B. Comprehensive sickle cell center-
Molecular basis for the sickling phenomenon.
P60HL-16005-05 0018 (SRC) KOSHY, MABEL. Comprehensive sickle cell center-
Comprehensive study-Natural history of sickle cell disease in adults
(human)
P60HL- 16005-05 0019 (SRC) LEVINSON, DENNIS J. Comprehensive sickle cell
center -Handling of uric acid in sickle cell anemia (human)
P60HL-16005-05 0020 (SRC) CHILCOTE, ROBERT R. Comprehensive sickle cell
center-Studies of the immunologic defect in sickle cell anemia
(human).
P60HL-1 6005-05 0021 (SRC) KOSHY, MABEL. Comprehensive sickle cell center-
Management of pregnancy in sickle cell anemia (human).
P60HL-16005-05 0022 (SRC) FRIED, WALTER. Comprehensive sickle cell center-
Regulation of erythropoiesis in patients with sickle cell anemia.
P60HI- 16005-05 9001 (SRC) BOWMAN, JAMES E. Comprehensive sickle cell
center-Core laboratory and counseling (human).
P60HI- 16008-06 (SRC) WHITTEN, CHARLES F, CHILDREN'S HOSPITAL, 3901
BEAUBIEN BLVD, DETROIT, MICH. Wayne State University comprehen-
sive sickle cell center.
P60HL-16008-06 0001 (SRC) WHITTEN, CHARLES F. Wayne State University
comprehensive sickle cell center-Patient care system (children,
adults).
P60HL- 16008-06 0009 (SRC) WHITTEN, CHARLES F. Wayne State University
comprehensive sickle cell center -Natural history of sickle cell anemia
(human).
P60HL- 16008-06 0011 (SRC) JONES, PERRY. Wayne State University comprehen-
sive sickle cell center-Education, screening and counseling.
P60HL-16008-06 0012 (SRC) SING, CHARLES F. Wayne State University com
prehensive sickle cell center-Central data management-Computer
system.
P60HL- 16008-06 0014 (SRC) BREWER, GEORGE J. Wayne State University com-
prehensive sickle cell center-Zinc and red blood cell metabolism in
sickle cell anemia (rats, human).
P60HL-16008-06 0015 (SRC) PRASAD, ANANDA S. Wayne State University com-
prehensive sickle cell center-Trace elements in sickle cell disease
(human).
P60HL- 16008-06 0016 (SRC) SIGN, CHARLES F. Wayne State University com-
prehensive sickle cell center-Red blood cell glycolysis in sickle cell
patients.
P60HL-1 6008-06 0017 (SRC) MIZUKAMI, HIROSHI. Wayne State University com
prehensive sickle cell center-Oxygen transport kinetics of pre- and
post-sickling cells (human).
P60HL- 16008-06 0018 (SRC) JOHNSON, ROBERT M. Wayne State University
comprehensive sickle cell center-Hemoglobin S and RBC membranes-
Pathogenesis of irreversibly sickled cells.
P60HL-1 6008-06 0019 (SRC) FROST, PHILIP. Wayne State University comprehen-
sive sickle cell center-Cell mediated immunity in sickle cell anemia
(human).
P60HL-1 6008-06 0020 (SRC) RUCKNAGEL, DONALD L. Wayne State University
comprehensive sickle cell center-Genetic and physiological studies of
sickle cell anemia (human).
R01HL-I6010-16 (PHY) WINEGRAD, SAUL, UNIVERSITY OF PENNSYLVANIA, DE-
PARTMENT OF PHYSIOLOGY, PHILADELPHIA, PA. Cellular basis of car-
diac contractility (frogs).
R01HL-1 6022-05 (AFY) EDELMAN, NORMAN H, COLLEGE OF MEDICINE, POST
OFFICE BOX 101, PISCATAWAY, N J. Determinants of the ventilatory
response to hypoxia (goats, cats).
R01HL- 16029-05 (TOX) PRYOR, WILLIAM A, LOUISIANA STATE UNIVERSITY, DE
PARTMENT OF CHEMISTRY, BATON ROUGE, LA. Bio-organic chemistry
of ozone, nitrogen dioxide and tobacco smoke.
R01HL-16037-06 (PHRA) LEFKOWITZ, ROBERT J, DUKE UNIVERSITY, MEDICAL
SCIENCE BLDG IB, DURHAM. N C. Molecular properties of cardiac
adrenergic receptors.
R01HL-I6052-0S (CVB) AKERA, TAI, MICHIGAN STATE UNIVERSITY. B445 LIFE
SCIENCE BUILDING, EAST LANSING. MICH. Cardiac glycosides-
Mechanism of inotropic action (dogs).
RO I HL- 16059-06 (MET) JONAS, ANA, UNIVERSITY OF ILLINOIS, 517 MEDICAL
SCIENCES BUILDING , URBANA, ILL. Structure and function of serum
lipoproteins (cattle, human).
ROIHL-1 6066-05 (CVA) HEISTAD, DONALD D, UNIVERSITY OF IOWA HOSPITALS,
DEPARTMENT OF INTERNAL MED, IOWA CITY, IOWA. Studies on neu-
rogenic control of the circulation (human, dogs).
ROIHL-1 6076-06 (CVA) MOORE, E NEIL, UNIVERSITY OF PENNSYLVANIA, 3800
SPRUCE STREET, PHILADELPHIA, PA. Electrophysiology of fibrillation
and defibrillation (human).
ROIHL-1 6087-05 (BBCB) LA MAR, GERD N, UNIVERSITY OF CALIFORNIA. DEPART-
MENT OF CHEMISTRY, DAVIS, CALIF. Structural and dynamic study of
model heme complexes (yeast).
ROIHl-16093-05 (BBCB) OLSON, JOHN S, RICE UNIVERSITY, DEPARTMENT OF
BIOCHEMISTRY, HOUSTON. TEX. Functional properties of hemoglobin
and erythrocytes.
ROIHL-1 6094-06 (CVA) FRIEDMAN, JULIUS J, INDIANA UNIVFRSITY, HOC WCSI
MICHIGAN STRffI, INDIANAPOLIS, INO The dynamics ol miciocircula
lory function (dogs)
R01HL-16I01-05 (BBCB) OENNIS, ROBERT •, UNIVERSITY OF ILLINOIS. BOX 15,
URBANA III Piolem lipid interaction Ibacleria, models)
P01HL-1 61 17-05 (HEP) PRESSMAN, BERTON C, UNIVtRSIIY OF MIAMI, P 0 BOX
520875, MIAMI, FLA Ion movements and membranes in cardiovascu
lar control
P01HL-I61 17-05 0001 (HEP) BAERWALD, ROY J. lon movements and mem
branes m cardiovascular control Developmental studies of contractile
cell junctions (rats, rabbits, elasmobranch)
P01HL-16I 17-05 0002 (HEP) CASWELL, ANTHONY P. Ion movements and
membranes in cardiovascular control Fluorescence and excrtation con
traction coupling in heart (frogs)
P01HL-161 17-05 0003 (HEP) HAYNES, DUNCAN. Ion movements and mem
branes in cardiovascular control-Fast kinetic study o( calcium mem-
brane interactions.
P01HL-161 17-05 0004 (HEP) LANDOWNE, DAVID. Ion movements and mem
branes in cardiovascular control Optical studies ol excitation contrac
tion coupling (frogs, snakes)
P01HL-161 17-05 0005 (HEP) PALMER, ROGER F. Ion movements and mem-
branes in cardiovascular control- Properties of isolated cell mem-
branes (rabbits, cats)
POlHl-161 17-05 0006 (HEP) POTTER, LINCOLN T. Ion movements and mem-
branes in cardiovascular control Neuroreceptors and cellular excita-
tion (fish).
P01HL-16n7-05 0007 (HEP) PRESSMAN, BERTON C. lon movements and mem-
branes in cardiovascular control Physiological and molecular proper-
ties of ionophores (dogs, rabbits)
P01HL-1 61 17-05 0008 (HEP) VANBREEMEN, CORNEUS. Ion movements and
membranes in cardiovascular control- Arterial smooth muscle calcium
fluxes and contractility (rabbits)
P01HL-1 61 18-06 (HLBB) PIERCE, JOHN A, WASHINGTON UNIVERSITY. 660 SOUTH
EUCLID, ST LOUIS, MO. Study of emphysema.
P01HL-1 61 18-06 0003 (HLBB) STARCHER, BARRY C. Study of emphysema
Degradation of collagen and elastin (human, hamsters, mice).
P01HL-1 61 18-06 0004 (HLBB) SENIOR, ROBERT M. Study of emphysema -
Metabolic activity of pulmonary connective tissue (human, hamsters).
P01HL-1 61 18-06 0005 (HLBB) KUHN, CHARLES, III. Study of emphysema-
Mechanisms of elastase emphysema (mice).
P01HL-1 61 18-06 0006 (HLBB) YU, SHIU YEH. Study of emphysema-Metabolism
of elastin (hamsters).
R01HL-161 19-05 (SGYB) HARRISON, DAVID E, JACKSON LABORATORY. BAR HAR-
BOR, MAINE. Spleen and marrow allografts in hereditary anemia
(mice).
R01HL-161 35-05 (CVA) HOGAN, PERRY M, S U N Y, DEPARTMENT OF PHYSIOLO-
GY, BUFFALO, N Y. Mechanisms of cardiac autorhythmicity (dogs,
bats).
P01HL-1 61 37-05 (HEP) SCARPELLI, EMILE M, ALBERT EINSTEIN COLL OF MED.
1300 MORRIS PARK AVENUE. BRONX. N Y. Alveolar biology.
P01HL-I6137-05 0001 (HEP) COLACICCO, GIUSEPPE. Alveolar biology -Chemi-
cal characterization of surfactant system-Lipid and lipid protein frac-
tions.
P01HL-1 61 37-05 0004 (HEP) FROSOLONO, MICHAEL F. Alveolar biology-Sub-
cellular processes and controls in the surfactant system (animals).
P01HL-1 61 37-05 0008 (HEP) WITTNER, MURRAY. Alveolar biology -Macromolecu-
lar events in pulmonary cells in toxic environments (animals).
P01HL-16137-05 0013 (HEP) CONDORELLI, SALVATORE. Alveolar biology-
Development and pathology of surfactant-Formation of alveolar
(rabbits, sheep)
ROIHL-1 61 50-05 (HEM) MANN, KENNETH G, MAYO FOUNDATION. 200 FIRST
STREET SOUTHWEST, ROCHESTER, MINN. Primary structure of
prothrombin (cattle, human).
R01HL-161S2-06 (CVA) MORAD, MARTIN, UNIVERSITY OF PENNSYLVANIA. 37TH
& HAMILTON WALK, PHILADELPHIA. PA. Electrophysiology of neonatal to
adult heart (cats, frogs, guinea pigs).
ROIHL-1 61 54-05 (SGYA) ZAPOL, WARREN M, MASSACHUSETTS GENERAL
HOSPITAL, ANESTHESIA DEPARTMENT, BOSTON, MASS. Membrane lung
perfusion for acute respiratory failure (sheep, baboons).
R01HL-16166-05 (BBCA) CHAN, SHUNG K, UNIVERSITY OF KENTUCKY, DEPART-
MENT OF BIOCHEMISTRY, LEXINGTON, KY. Structure of alpha-1-an-
titrypsin in relation to emphysema (human).
ROIHL-1 6206-04 (CVB) DEPAUMA, RALPH G, UNIVERSITY HOSPS OF CLEVEUND,
2065 ADELBERT ROAD, CLEVELAND, OHIO. Regression of atheros-
clerotic plaques (monkeys, dogs).
R01HL-16219-OS (CVB) BAGDADE, JOHN D, PROVIDENCE MEDICAL CENTER, 500
17TH AVE, C-34008, SEATTLE. WASH. Mechanisms of atherogenesis in
chronic uremia (human, rats).
R01HL-16233-0S (CVB) BONILLA, CARLOS A, COLORADO STATE UNIVERSITY,
DEPT OF PHYSIO & BIOPHYSICS, FORT COLLINS, COLO. Molecular car-
diology of MDP-induced left ventricular failure (dogs).
ROIHL-1 6236-04 (CVA) NEREM, ROBERT M, OHIO STATE UNIVERSITY, 1900 COF-
FEY ROAD, COLUMBUS, OHIO. Detailed characteristics of coronary
blood flow (horses, dogs, calves).
R01HL-16238-0S (HEM) MAGNUSSON, STAFFAN M, AARHUS UNIVERSITET,
DEPT OF MOLECULAR BIOLOGY, ARHUS, DENMARK. Protein structure in
coagulation and fibrinolysis (human).
ROIHL-1 6240-05 (CVB) HUGHES, MAYSIE J, TEXAS TECH UNIVERSITY, POST OF-
FICE BOX 4569, LUBBOCK, TEX. The cardiac histamine receptor
(rabbits, guinea pigs).
ROIHL-1 6246-06 (SGYA) ENGLE, MARY A, CORNELL UNIVERSITY, 1300 YORK
AVENUE, NEW YORK. N Y Immunologic studies in postpericardiotomy
syndrome (human).
POIHl-16251-06 (HLBA) SINGER, THOMAS P, VETERANS ADMINISTRATION HOSP.
4150 CLEMENT STREET. SAN FRANCISCO, CALIF. Membrane-bound en-
zymes in heart and other tissues.
POIHL-16251-06 0001 (HLBA) KENNEY, WILLIAM C. Membrane-bound enzymes
in heart and other tissues -Structure of covalently bound flavins
(bacteria, yeast, mammals).
POIHl-16251-06 0002 (HLBA) KENNEY, WILLIAM C. Membrane-bound enzymes
in heart and other tissues-Structural basis of regulation of cardiac
succinate dehydrogenase.
POIHL-16251-06 0003 (HLBA) KEARNEY, EDNA B. Membrane-bound enzymes in
heart and other tissues-Regulation of cardiac succinate
dehydrogenase (yeasts, mammals).
PROJECT NUMBER AND INVESTIGATOR ADDRESS
K)IHl-162SI.06 0004 (HLBA) KEARNEY, EDNA B. Membrane-bound enzymes in
heart and other tissues-Biosynthesis and degradation of succinate
dehydrogenase, histidyl (yeast, mammal)
P01HH6251-06 0007 (HIBA) SINGER, THOMAS P. Membranebound enzymes
in heart and other tissues-Flavins and flavoproteins
POl HI.) 625 1-06 0008 (HIBA) SINGER, THOMAS P. Membranebound enzymes
m heart and other tissues-lronsulfur centers and phospholipids
modulation of succinate dehydrogenase
P01Hl.16251.06 0009 (HIBA) SINGER, THOMAS P. Membranebound enzymes
in heart and other tissues-NAOH dehydrogenase and site I of oxida-
tive phosphorylation (yeast)
P0IHI.162S1.06 0010 (HIBA) SINGER, THOMAS P. Membranebound enzymes
m heart and other tissues-Reversible activation of l-amino acid ox-
idase (snakes).
R01Hl.I6254.05 (AFY) SMITH, lYNWOOD S, UNIVERSITY OF WASHINGTON
FISHERIES RESEARCH INST, WH-10, SEAHLE, WASH. Pathogenesis of
bubble and clot formation (fish).
R01HH6260-04 (RAD) GRAMIAK, RAYMOND, UNIVERSITY OF ROCHESTER 601
ELMWOOD AVENUE, ROCHESTER, N Y. Development of clinical cine ul-
trasound cardiography.
R01Hl.16292.0S (SGYA) BUCKBERG, GERAID D, UNIVERSITY OF CALIFORNIA
OIV OF THORACIC SURGERY, LOS ANGELES, CALIF. Surgery and non-ob^
struclive coronary insufficiency
R01HH6292.05 0002 (SGYA) MAIONEY, JAMES V, JR. Surgery and nonob
structive coronary insufficiency-Effects of hypothermia during car-
diopulmonary bypass (dogs)
R01Hl.16292.05 0009 (SGYA) MAIONEY, JAMES V. JR. Surgery and non-ob-
structive coronary insufficiency-Exercise and supply-demand balance
(human).
ROIHI.16292.05 0010 (SGYA) MAIONEY, JAMES V, JR. Surgery and non-ob-
structive coronary insufficiency-Effects of exercise on flovi distribution
(dogs).
ROIHH 6292-05 0017 (SGYA) BUCKBERG, GERAID D. Surgery and nonob
structive coronary insufficiency-Cardiopulmonary resuscitation
(human).
R01H1.16292-0S 0018 (SGYA) BUCKBERG, GERAID D. Surgery and nonob
structive coronary insufficiency-Unavoidable subendocardial perfusion
caused by venting and hypothermia (dogs)
R01Hl.16292.05 0019 (SGYA) BUCKBERG, GERAID D. Surgery and non-ob-
structive coronary insufficiency-Distortion of subendocardial vessels in
infant hearts (dogs).
R01Hl.16292.05 0020 (SGYA) BUCKBERG, GERAID D. Surgery and non-ob-
structive coronary insufficiency-Limitation of transthoracic ECG in de-
tecting subendocardial ischemia (dogs)
R01HL-16292-0S 0021 (SGYA) BUCKBERG, GERAID D. Surgery and nonob
structive coronary insufficiency-Pulsatile assistance on subendocardi-
al perfusion during bypass (dogs).
R01 HI- 16294-04 (MET) WATSON, JOHN A, UNIVERSITY OF CALIFORNIA DEPT OF
BIOCHEM & BIOPHYSICS, SAN FRANCISCO, CALIF. Effectors of
cholesterol synthesis (rats).
ROIHl-16315-05 (CVB) SCHRAMM, LAWRENCE P, JOHNS HOPKINS UNIVERSITY
BIOMEDICAL ENGINEERING DEPT, BALTIMORE, MD. Analysis of interac-
tion between CNS vasomotor systems (cats, rats)
ROIHl-16318-21 (PHRA) HOKIN, lOWELl E, UNIVERSITY OF WISCONSIN 426 N
CHARTER STREET, MADISON, WIS Biochemistry and pharmacology of
Na-K transport
ROlHl.16320-05 (PHRA) ERDOS, ERVIN G, UNIVERSITY OF TEXAS, 5323 HARRY
HINES BOULEVARD, DALLAS. TEX Vasoactive peptides which stimulate
smooth muscles (rats, human).
ROlHL-16325-03 (CVA) KRONAUER, RICHARD E, HARVARD UNIVERSITY 324
PIERCE HALL, CAMBRIDGE, MASS. Breathing patterns in man '
ROIHl-16328-06 (CVA) HERMSMEYER, R KENT, DEPARTMENT OF PHARMACOLO-
GY, BASIC SCIENCE BUILDING, IOWA CITY, IOWA. Membrane electrical
properties of vascular muscle (human, animals)
ROlHl-16329-04 (SGYB) JARMAKANI, JAY M, UNIVERSITY OF CALIFORNIA DEPT
OF PEDIATRICS, LOS ANGELES, CALIF. Cardiac surgical effect on heart
function in infants (human).
ROlHl.16330-06 (PTHA) EVANS, MICHAEL J, SRI INTERNATIONAL, 333 RAVEN-
SWOOD AVENUE, MENLO PARK, CALIF. Aging-tissue injuiy and repair
R01HL.I6346-09 (HEM) lORAND, LASZIO, NORTHWESTERN UNIVERSITY
BIOCHEM & MOLEC BIOLOGY DEPT, EVANSTON, ILL. Enzyme assay ior
blood clotting (human).
R01HI-163S5-05 (HEM) DETWILER, THOMAS C, S U N Y DOWNSTATE MEDICAL
CTR, 450 CLARKSON AVENUE, BROOKLYN, N Y. Reactions of thrombin
and collagen with platelets (human).
ROlHl-16361.03 (HEM) SHAINOFF, JOHN R, CLEVEUND CLINIC FOUNDATION
9500 EUCLID AVENUE, CLEVEUND, OHIO. Fibrin complexes in inter^
mediary coagulation (human, rabbits),
ROl HI- 16364-04 (MET) PORTER, JOHN W, UNIVERSITY OF WISCONSIN 1215 LIN-
DEN DRIVE, MADISON, WIS. Regulation of lipid biosynthesis' and trans-
port (rats, swine, Xenopus).
R0IHL-1637S-04 (HEM) SIMONS, ELIZABETH R, BOSTON UNIVERSITY 80 EAST
CONCORD STREET, BOSTON, MASS. Investigation of hemoglobin S pro-
perties (human).
POlHl-16387.04 (HEP) SPAET, THEODORE H, MONTEFIORE HOSP & MED
CENTER, 111 EAST 210TH STREET, BRONX, N Y. The blood vessel and
thrombogenesis.
P01HL-I6387-04 0002 (HEP) PUSZKIN, ELENA. The blood vessel and throm-
bogenesis-Hormonal effects on thrombogenesis (rats rabbits)
POIHl-16387-04 0003 (HEP) SPAET, THEODORE H. The blood vessel and throm
bogenesis-Blood vessel healing (rabbits)
POIHL-16387-04 0004 (HEP) HATCHER, VICTOR. The blood vessel and throm-
bogenesis-Analysis of vascular basement membrane by enzymatic
methods (human),
POlHL.16387-04 0005 (HEP) SPAET, THEODORE H. The blood vessel and throm
bogenesis -Fluid engineering considerations in thrombogenesis
POlHl.16387-04 0006 (HEP) LITWAK, ROBERT S. The blood vessel and throm-
bogenesis-Mechanism of delayed vessel graft failure (dogs, rabbits)
POlHL.16387-04 0008 (HEP) SUSSMAN, IRA I. The blood vessel and throm-
bogenesis-Factor VIII in hemostasis (human, rabbits)
P01HL. 16387-04 0009 (HEP) TIELL, MELVIN I. The blood vessel and throm -
bogenesis-Role of pituitary gland in the pathogenesis of arterios-
clerotic lesions (rats).
548
R01HL-16390-05 (AFY) GRODINS, FRED S, UNIV OF SOUTHERN CALIFORNIA
UNIVERSITY PARK, LOS ANGELES, CALIF. Cardiopulmonary control
coupling in exercise (dogs).
■ 16403-05 (EDO DOYLE, JOSEPH T, ALBANY MEDICAL COLLEGE NEW
SCOTUND AVENUE, ALBANY. N Y. Prognostication by computer-
Analyzed vectorcardiogram (human).
-16411-04 (HEP) MULLER-EBERHARD, HANS J, RESEARCH INSTITUTE OF
SCRIPPS, 10666 N TORREY PINES ROAD, LA JOLLA, CALIF. Blood
systems in coagulation and vessel disease.
16411-04 0001 (HEP) MULLER-EBERHARD, HANS J. Blood systems in
coagulation and vessel disease-Molecular studies of the role of com-
plement in blood coagulation (human, rabbits)
16411-04 0002 (HEP) COCHRANE, CHARLES G. Blood systems in
coagulation and vessel disease- Early stages of coagulation and car-
diovascular disease (human, rabbits).
16411-04 0003 (HEP) EDGINGTON, THOMAS S. Blood systems in
coagulation and vessel disease-Molecular events involving the late
stages of coagulation (rabbits),
16411-04 0004 (HEP) MORRISON, DAVID C. Blood systems in coagula-
tion and vessel disease-Platelets reactions in vascular injury (human
animals).
16411-04 0005 (HEP) HUGH, TONY E. Blood systems in coagulation and
vessel disease -Chemical analysis of serum components associated
with coagulation (human, animal).
16411-04 0006 (HEP) ZIMMERMAN, THEODORE S. Blood systems In
coagulation and vessel disease-Factor Vll-lmmunochemistry and im-
munobiology (human, mice).
16412-04 (CVB) FOX, ARTHUR C, NEW YORK UNIVERSITY 550 FIRST
AVENUE, NEW YORK, N Y. Release of nucleosides from the ischemic
heart (human, dogs).
16419-03 (CVA) GHOSH, SANTIBRATA, NORTHWESTERN UNIVERSITY 303
EAST CHICAGO AVENUE, CHICAGO, ILL Arterial uptake of lipopro'tein-
Kinetic analysis (rabbits).
16420-02 (AFY) FULLER, ELLEN O, EMORY UNIVERSITY. DEPARTMENT OF
PHYSIOLOGY, ATLANTA, GA. Effect of training-detraining on the rat
heart.
16421.08 (HEM) LA CELLE, PAUL L, UNIVERSITY OF ROCHESTER 260 CRIT-
TENDEN BOULEVARD, ROCHESTER, N Y Determinants of RBC deforma-
bility and capillary flow (human, mice).
16430-05 (PHY) KNOX, CHARLES K, UNIVERSITY OF MINNESOTA 315 MIL-
LARD HALL. MINNEAPOLIS, MINN. Neural control of respiration (cats)
16436.04 (CVA) HESS, MARILYN E, UNIVERSITY OF PENNSYLVANIA DEPT
OF PHARMACOLOGY. PHILADELPHIA. PA. Role of calcium and thyroxine
in heart function (rats).
16437-05 (PHRA) HOLLANDER, WILLIAM, UNIVERSITY HOSPITAL 750
HARRISON AVENUE, BOSTON, MASS. Drug treatment of atherosclerosis
(rabbits, monkeys).
-16445-05 (PC) FULLER, GERALD M, UNIVERSITY OF TEXAS. GALVESTON,
TEX. Regulation of plasma protein biosynthesis (rats rabbits)
•16454-03 (CVB) STEKIEl, WILLIAM J, MEDICAL COLLEGE OF WISCONSIN
561 NORTH 15TH STREET. MILWAUKEE. WIS. Vascular muscle reactivi-
ty in hypertension (human, rats),
■16461.05 (EDO STARR, ALBERT, UNIVERSITY OF OREGON. 3181 S W SAM
JACKSON PARK ROAD. PORTLAND, OREG. Late results of valve replace-
ment-Computer analysis (human).
16463-05 (CVA) INGRAM, ROLAND H, JR, PETER BENT BRIGHAM
HOSPITAL, 721 HUNTINGTON AVENUE, BOSTON, MASS. Localization of
airways obstruction and responses.
16471.05 (MCHA) STORK, GILBERT, COLUMBIA UNIVERSITY, BOX 666
HAVEMEYER HALL, NEW YORK, N Y. Cardioactive alloyohim bines and
related indole alkaloids.
16474-05 (BBCB) FRIEDMAN, HAROLD I, S U N Y - AT STONY BROOK
DEPARTMENT OF CHEMISTRY. STONY BROOK, N Y. Antibiotic-ion in-
teractions (model membranes).
16484.04 (RAD) AMPLATZ, KURT, UNIVERSITY OF MINNESOTA, DEPART-
MENT OF RADIOLOGY, MINNEAPOLIS, MINN. Radiographic ventricu-
lometry for coronary heart disease (human).
16487-05 (RAD) PRYOR, T ALLAN, UTTER DAY SAINTS HOSPITAL 325 8TH
AVENUE SALT LAKE CITY, UTAH. Computer controlled two dimensional
echocardiography.
16489.04 (CVB) GATES, JOHN A, VANDERBILT UNIVERSITY, DEPARTMENT
OF PHARMACOL()GY. NASHVILLE. TENN. Renal prostaglandins-Xnthes
IS and function (human, dogs, rats).
16490.04 (GMB) AINSWORTH, STERLING K, MEDICAL UNIV OF SOUTH
CAROLINA, 171 ASHLEY AVENUE, CHARLESTON, S C Structural bas's
of nephron filtration (rats, rabbits)
16496-04 (CVB) ROMERO, JUAN C, MAYO FOUNDATION, 200 FIRST
STREET SOUTHWEST, ROCHESTER. MINN. Prostaglandins and renrex
perimental hypertension (rabbits)
16507-04 (CBY) GILULA, NORTON B, ROCKEFELLER UNIVERSITY 1230
YORK AVENUE, NEW YORK. N Y. Heart cell interactions and eil unc-
tion biogenesis (mice, rats, rabbits)
-16511-04 (CVB) KAMPINE, JOHN P, VETERANS ADMINISTRATION CENTER
5000 WEST NATIONAL AVENUE, WOOD, WIS. Sympathetic afferent ac^
tivity of cardiac origin (dogs, monkeys).
■16512-04 (PC) MEANS, ANTHONY R, BAYLOR COLLEGE OF MEDICINE
200 M()URSUND AVENUE, HOUSTON, TEX. Lipoprotein metabS and
hormonal regulation (chickens).
■16524-02 (MCHA) PORTOGHESE, PHILIP S, UNIVERSITY OF MINNESOTA
COLLEGE OF PHARMACY, MINNEAPOLIS, MINN. Selective iStorsoi
prostaglandin biosynthesis (dogs).
16549-04 (PHRA) YODA, ATSUNOBU, UNIVERSITY OF WISCONSIN. 371
MEDICAL SCIENCES BUILDING , MADISON, WIS. Cardiotonic steroid-NaK
ATPase interactions (cattle).
16553-05 (RAD) ATKINS, HAROLD L, BROOKHAVEN NATIONAL UBORATO-
RY, ASSOCIATED UNIV INC, UPTON, N Y. Diagnosis of myocardial in-
tarction by radioisotopes (mice, rats, goats).
16567-04 (CVB) DEHAAN, ROBERT L, DEPT OF ANATOMY, EMORY UNIVER-
SITY, ATUNTA, GA. Differentiation of the heart-cell membrane (mice
chick).
16577-04 (MET) SCHOTZ, MICHAEL C, UNIVERSITY OF CALIFORNIA DE
PARTMENT OF MEDICINE, LOS ANGELES, CALIF. Lipoprotein lipase
chemistry and function (rats, cattle, human).
ROIHL
POIHL-
P01HL-
POIHL-
P01HL-
P01HL-
P01HL
POIHL-
ROIHL.
ROIHL
ROIHL.
ROIHL.
ROIHL
ROIHL
ROIHL
ROIHL-
R01HL-
R01HL.
ROIHL
ROIHL
ROIHL-
ROIHL
R01HL-
R01HL
R01HL-
R01HL-
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549
PROJECT NUMBER AND INVESTIGATOR ADDRESS
R01Hl-l«$*0-04 (COM) KINO, WILLIAM S, RANO CORPORATION. 1/00 MAIN
STREET. SANTA MONICA. CALIF Mathematical models lor studying
sicklecell disease
«01Hl-165ia.05 (SOVB) MOCKROS. LYLl f. NORTHWESTERN UNIVERSITY. DEPT
Of Civil ENGINtFRING, EVANSION. Ill Artilicial lun|5 (dogs)
R0IHL-I6SS7-04 (CVB) MAIINOW, MANUEL R, OREGON REG PRIMATE RES
CENTER. 505 N W. 185TH AVENUE. BEAVERTON. OREG Cholesterol
binding saponins and athetosclerosis (monheys)
R01HL-1 6388-05 (PBC) EHRHART. ALLEN. CIEVEUND CLINIC FOUNDATION. 9500
EUCLID AVENUE. CLEVEUND. OHIO Collagen synthesis in atheros-
clerosis (dogs. rats, rabbits, human)
R0IHL-I660I-0S (BBCB) OREER, JONATHAN. COLUMBIA UNIVERSITY. DEPT OF
BIOLOGICAL SCIENCES. NEW YORK. N Y Structure and lunction ol
blood proteins (human, cattle)
R01HL-14603-05 (CVB) PIRANI. CONRAD L. COLUMBIA UNIVERSITY. 630 WEST
168TH ST. NEW YORK, N Y Human and experimental lenal diseases
(animals)
R01HL-I6606-11 (PHY) JULIAN. FRED J, BOSTON BIOMEDICAL RES INST. 20
STANIFORD STREET. BOSTON. MASS Contraction in heart and other
striated muscles (irogs)
PO I HI- 1 6607 -OS (HEPA) INESI. GIUSEPPE, UNIVERSITY OF THE PACIFIC. 2155
WEBSTER STREET. SAN FRANCISCO. CALIF. Calcium ion and control of
cardiovascular lunction
PO1HL-I6607-0S 0001 (HEPA) COHEN, JOEL A. Calcium ion and control of car-
diovascular function-Bilayer lipid membranes, antibiotic probes, and
SR function.
POIHL-16607-0S 0003 (HEPA) INESI, GIUSEPPE. Calcium ion and control of car-
diovascular function -Calcium transport in sarcoplasmic membranes
(animals).
P01HL-I6607-05 0005 (HEPA) MURPHY. ALEXANDER J. Calcium ion and con-
trol ol cardiovascular function -Chemical modifications of the sar-
coplasmic reticulum membranes (rabbits).
POIHl-16607-05 0006 (HEPA) SABBADINI. ROGER. Calcium ion and control of
cardiovascular lunction -Sarcomere and contractile dynamics of
striated muscle cells (animals).
POIHL-16607-05 0007 (HEPA) SCALES. DONALD. Calcium ion and control of
cardiovascular function -Ultrastructure and conformation in sar-
coplasmic reticulum (rabbits).
R01HL-l66n-04 ("HRA) HEGYVARY. CSABA. ST LUKES MEDICAL CENTER. 1753
WEST CONGRESS PARKWAY. CHICAGO. ILL. Digitalis-receptor of the
heart (guinea pigs. rats).
R01HL-1 6626-05 (SSS) HOYER. LEON W. UNIVERSITY OF CONNECTICUT. MEDICINE
DEPARTMENT. FARMINGTON. CONN. Studies of antibodies to antihemo-
philic factors (human, rabbits).
ROIHL-16628-05 (PC) FALL, R RAY. UNIVERSITY OF COLORADO. DEPARTMENT OF
CHEMISTRY. BOULDER. COLO. Regulation of lipid metabolism (rats).
R01HL-1 6633-04 (HEM) KINGDON. HENRY S, UNIVERSITY OF NORTH CAROLINA.
DEPT OF MEDICINE. CHAPEL HILL. N C. Chemistry and biology of fac-
tor IX activator (human, mice. rats).
ROlHL-16634-13 (PC) MAJERUS. PHILIP W. WASHINGTON UNIVERSITY. 4566
SCOTT AVENUE, ST LOUIS. MO. Regulation of metabolism in
fibroblasts and platelets (human, rabbits, sheep).
R01HL-16637-04 (MBY) ZAK. RADOVAN H. UNIVERSITY OF CHICAGO. 950 EAST.
59TH STREET, CHICAGO. ILL. Development and regression of cardiac
hypertrophy (rats).
R01HL-1 6642-05 (HEM) COUVIAN. ROBERT W. HOSPITAL/UNIV OF PENNSYLVANIA.
MEDICINE DEPARTMENT. PHILADELPHIA. PA. Biochemistry and
pathophysiology of plasma kallikrein (human, animals).
R01HL-1 6643-02 (CVB) ROSENBLUM, WILLIAM I. VIRGINIA COMMONWEALTH
UNIV. BOX 17. DIV OF NEUROPATHOLOGY . RICHMOND. VA. Fluorocar-
bon emulsions as artificial blood (animals).
ROIHL- 16646-05 (HEM) HAWIGER. JACK J. VANDERBILT UNIVERSITY. 21ST
AVENUE SOUTH, NASHVILLE, TENN. Pathoblology of thromboembolic
disorders (human).
R01 HI- 1 6647-05 (BIO) HASS, LOUIS F, MILTON S HERSHEY MEDICAL CTR, DEPT
OF BIOLOGICAL CHEMISTRY, HERSHEY, PA. Studies on the control of
sickle cell crisis (human).
R01HL-I6648-16 (CVB) MANNING, JOHN W. EMORY UNIVERSITY, PHYSIOLOGY
DEPARTMENT, ATLANTA. GA. Integrated control of cardiovascular ac-
tivity (cats).
R01HL-1665I-05 (EDC) LYONS. HAROLD A. OOWNSTATE MEDICAL CENTER. 450
CLARKSON AVENUE. BROOKLYN. N Y. Evaluation of steroid therapy in
sarcoidosis (human).
R01HL-1 6654-06 (HEM) GABUZDA. THOMAS G. UNKENAU HOSPITAL, LAN
CASTER & CITY LINE AVENUES . PHILADELPHIA, PA. Regulation in
developing erythroid cells (human).
R01HL-16656-06 (CVB) HORWITZ, LAWRENCE D. UNIVERSITY OF TEXAS. 7703
FLOYD CURL DRIVE. SAN ANTONIO, TEX. Left ventricular function in ex-
ercise (dogs).
R01HL-1 6657-06 (CVB) BROWN, ARTHUR M. UNIVERSITY OF TEXAS MEDICAL BR,
DEPT OF PHYSIOLOGY & BIOPHYS, GALVESTON, TEX. Innervation of
coronary arteries and heart (rats).
ROIHL-16658-05 (CVB) SCHNEIDER, EDWARD G, UNIVERSITY OF TENNESSEE.
894 UNION AVENUE. MEMPHIS. TENN. Intrarenal regulation of sodium
reabsorption.
R01HL-1 6660-06 (BBCB) BITTMAN, ROBERT. QUEENS COLLEGE -CUNY.
CHEMISTRY DEPARTMENT. FLUSHING. N Y. Phospholipid-cholesterol
and phospholipid-protein interactions.
R01HL-1 6666-05 (PHY) WAGNER. ROGER C. UNIVERSITY OF DELAWARE. 117
WOLF HALL, NEWARK. DEL Micropinocytosis in isolated capillary en-
dothelium.
R01HL-1 6674-05 (CVA) GATZY. JOHN T. JR, UNIVERSITY OF NORTH CAROLINA.
DEPARTMENT OF PHARMACOLOGY. CHAPEL HILL. N C. Airborne metals
and lung permeability (bullfrogs, rats).
ROIHl-16675-05 (HEM) GUTNISKY. ABRAHAM. INST DE NEUROBIOLOGIA,
OBLIGAOO NRO 2490. BUENOS AIRES. ARGENTINA. Human urinary
erythropoietin collection.
ROIHL-1 6678-03 (BBCA) DOWBEN. ROBERT M, UNIVERSITY OF TEXAS, 5323
HARRY HINES BLVD. DALUS, TEX 75235. Fluorescent probe studies of
heart muscle proteins (rabbit, dog).
POIHl-16683-04 (HEP) MORALES. MANUEL F. UNIVERSITY OF CALIFORNIA. SAN
FRANCISCO, CALIF. Function and growth of cardiac and skeletal
muscle.
P0)HL-l66a3-04 0001 (HIP) BOREJDO. JULIAN. Function and growlh ol car
diac and skeletal muicle light chains ol the skeletal and cardiac
myosin molecule (rabbits, Irof.)
POIHL-16683-04 0002 (HEP) MENOELSON, ROBERT A. Function and growth ol
cardiac and skeletal muscle Myosin, actin, ATP. interaction in tolu
lion
PO I HI- 1 6683-04 0003 (HEP) LEUNG, JOSEPH. Function and growth of cardiac
and skelijUl muscle Movements o( SI moieties in muscle libers
POIHL-16683-04 0006 (HEP) DUKE, JOSEPH A. function and growth ol cardiac
and skeletal muscle Chemical studies ol the contractile system
Development of new reagents
ROIHL-16686-04 (BIO) WHARTON. DAVID C. UNIVERSITY OF TEXAS, BIOCHEMIS
TRY DEPARTMENT. SAN ANTONIO. TEX. Properties ol cytochrome ox
idase (cattle, bacteria)
ROIHL-16706-04 (CVB) LEE. KWANG 5. S U N Y OOWNSTATE MED CTR, 450
CLARKSON AVENUE. BROOKLYN. N Y Excitation contraction coupling
and heart failure (dogs, rabbits)
ROIHL- 167 1 0-03 (CVB) KOLBECK. RALPH C, MEDICAL COLLEGE OF GEORGIA,
1120 15TH STREET. AUGUSTA. GA Myocardial subcellular localization
ol calcium (dogs)
ROlHL-16711-05 (SGYB) EVANS. EVAN A. OUKE UNIVERSITY. OEPT OF BIOMEOI
CAL ENGR. DURHAM. N C RBC and endothelial membrane material
characteristics (human)
ROIHL-1 67 14-05 (PTHA) SHEPRO. DAVID. BOSTON UNIVERSITY. 2 CUMMINGTON
STREET. BOSTON. MASS Endothelial cell communication in homeosta-
sis (human, mammals)
ROlHL-1 6720-02 (HEM) GANGULY. PANKAJ, ST JUDE CHILDREN'S RES HOSP,
332 N LAUDERDALE. MEMPHIS. TENN. Platelet aggregation (human).
ROIHL-16725-03 (CVA) KING. RICHARD J. UNIVERSITY OF TEXAS. 7703 FLOYD
CURL DRIVE. SAN ANTONIO. TEX. Physiological regulation of pulmonary
surfactant (dogs. rats).
ROlHL-16730-03 (MBY) AIELLO. EDWARD L. FORDHAM UNIVERSITY. BIOLOGICAL
SCIENCES OEPT, BRONX. N Y. Physiology of mucociliary transport
(rats, frogs, rabbits).
ROlHL-16746-04 (MCHB) BOROWITZ. IRVING J. YESHIVA UNIVERSITY. 2495 AM-
STERDAM AVENUE. NEW YORK. N Y. Design of ion-selective molecules.
POlHL-16748-05 (HEP) BELLANTI, JOSEPH A. GEORGETOWN UNIVERSITY. 3900
RESERVOIR ROAD. WASHINGTON. D C. Cellular and immunological
basis of pulmonary diseases.
POlHL-16748-05 0001 (HEP) SCHWARTZ. SORELL L. Cellular and immunological
basis of pulmonary diseases -Mechanisms of alveolar macrophage
function and dysfunction (human, rabbits).
P01HL-16748-0S 0002 (HEP) HERSCOWITZ. HERBERT B. Cellular and immu
nological basis of pulmonary diseases -Immunological function of al-
veolar macrophages (rabbits, sheep, mice).
POIHL-1 6748-05 0004 (HEP) BELLANTI. JOSEPH A. Cellular and immunological
basis of pulmonary diseases-Cellular and immunological processes in
pulmonary defense systems.
POlHL-1 6748-05 0006 (HEP) YEAGER. HENRY. JR. Cellular and immunological
basis of pulmonary diseases-Sarcoidosis-Studies with bronchial
lavage (human).
ROlHL-16757-04 (HEM) GENGOZIAN, NAZARETH. OAK RIDGE ASSOCIATED
UNIVS. POST OFFICE BOX 117. OAK RIDGE. TENN. 'Autoimmune' throm-
bocytopenia (monkey).
ROlHL-16759-05 (RAD) MORITZ, WILLIAM E. UNIVERSITY OF WASHINGTON. RM
334. AREOSPACE RES LAB FL20. SEATTLE. WASH. Ultrasonic measure-
ment of cardiac geometry and flow.
R0IHL-16760-0S (CVB) SPARKS. HARVEY V. UNIVERSITY OF MICHIGAN.
PHYSIOLOGY DEPARTMENT. ANN ARBOR, MICH. Dynamic control of
coronary blood flow (dogs).
ROlHL-16768-04 (CVA) FRONEK. KITTY. UNIVERSITY OF CALIFORNIA. AMES-BIOEN-
GINEERING. M-005. LA JOLLA, CA. The sympathetic nervous system
and the arterial wall (rabbits, pigeons).
POIHL-1 6769-05 (HEP) MYRVIK, QUENTIN N. BOWMAN GRAY SCHOOL OF
MEDICINE. DEPT OF MICROBIOLOGY & IMMUNOL. WINSTON-SALEM. N
C. Pathobiologic and host defense reactions in the lung.
POIHL-1 6769-05 0002 (HEP) MCCALL. CHARLES E. Pathobiologic and host
defense reactions in the lung-Pathogenesis of complement dependent
injury to the lungs (rabbits).
POIHL-1 6769-05 0003 (HEP) MYRVIK, QUENTIN N. Pathobiologic and host
defense reactions in the lung-Pathobiologic mechanisms of delayed
sensitivity reactions in the lung (animals).
POIHL-1 6769-05 0004 (HEP) KREGER. ARNOLD S. Pathobiologic and host
defense reactions in the lung-Pathogenesis of Pseudomonas and Ser-
ratia pneumonias (rabbits).
POIHL-1 6769-05 0007 (HEP) HEISE. EUGENE R. Pathobiologic and host defense
reactions in the lung-lmmunogenetic factors in sarcoidosis (human).
POlHL-1 6769-05 0008 (HEP) JOHNSON. JOSEPH E. Pathobiologic and host
defense reactions in the lung-Pulmonary immunocytologic defense
mechanisms against bacteria (human, animals).
POlHL-16769-05 0009 (HEP) MYRVIK. QUENTIN N. Pathobiologic and host
defense reactions in the lung-Electron microscopy and tissue culture
core laboratory.
POlHL-1 6769-05 0010 (HEP) MYRVIK, QUENTIN N. Pathobiologic and host
defense reactions in the lung -Bronchus associated lymphoid tissue
and delayed hypersensitivity (rabbits).
POlHL-1 6769-05 0011 (HEP) LOVE. SAMUEL H. Pathobiologic and host defense
reactions in the lung-Core-Laboratory for biomedical preparation
(rabbits).
ROlHL-1 6774-04 (SSS) MORTON. NEWTON E. UNIVERSITY OF HAWAII. 1980
EAST WEST ROAD. HONOLULU. HAWAII. Genetic epidemiology of hyper-
lipemia (Honolulu).
ROT HL-1 6784-03 (AFY) HYDE. RICHARD W, UNIVERSITY OF ROCHESTER. PULMO-
NARY UNIT. ROCHESTER. N Y. Lung tissue and water volume (human,
dogs).
ROlHL-16791-03 (COM) ACKERMAN. EUGENE. UNIVERSITY OF MINNESOTA. BOX
511. MAYO MEMORIAL BLD6. MINNEAPOLIS. MINN. Computer linkage
for a dual camera system.
ROlHL-16796-05 (MET) SCALLEN. TERENCE J, UNIVERSITY OF NEW MEXICO, 915
STANFORD N E, ALBUQUERQUE, N MEX. Cholesterol regulation by HMG-
CoA reductase (rats, human).
ROl HL-1 6807-02 (MET) JENSEN. ROBERT G, UNIVERSITY OF CONNECTICUT. U-17.
DEPT OF NUTRITIONAL SCIS. STORRS. CONN. Lipid structure of normal
and hyperlipoproteins (human).
I
PROJECT NUMBER AND INVESTIGATOR ADDRESS
R01HL.16828-04 (CVA) lONGMUIR, IAN S, NORTH CAROLINA STATE UNIV POST
OFFICE BOX 5050. RALEIGH. N C. Gradient and transport of oxygen in
frssue and organs (mammals).
ROlHl-l 6830-05 (RAD) HUNTSMAN, lEE I, UNIVERSITY OF WASHINGTON CENTER
FOR BIOENGINEERING. SEAHLE. WASH. Non-invasive determination of
aortic blood velocities (human).
P01Hl.I6833.04 (HEP) BENSON, ELUS S, UNIVERSITY OF MINNESOTA BOX 198 -
MAYO. MINNEAPOLIS. MINN. Hemoglobin and red cell system <n
hemoglobinopathies
POIHI.16833.04 0001 (HEP) BENSON, ElUS S. Hemoglobin and red cell system
in hemoglobinopathies-Motility, association and ligand binding in
hemoglobin-Hydrogen exchange.
P01HH 6833-04 0002 (HEP) ROSENBERG, ANDREAS. Hemoglobin and red cell
system m hemoglobinopathies-Polymerization and gel formation in
solutions of hemoglobin A and S (human)
POtHl.16833.04 0003 (HEP) BENSON, EUlS S. Hemoglobin and red cell system
'" '^«'"<'el'''""oPa"'ies-Oxygen binding curves and equilibria (human)
POIHL-16833-04 0004 (HEP) BENSON, EUlS S. Hemoglobin and red cell system
m hemoglobinopathies-Purification and fractionation of hemoglobin A
and S (human).
POlHl-16833-04 0006 (HEP) LUMRY, kUFUS. Hemoglobin and red cell system in
hcmoglobinopathies-Role of water in function of hemoglobin and
myoglobin (human).
P01HH6833.04 0008 (HEP) BIACKSHEAR, PERRY L JR. Hemoglobin and red
cell system in hemoglobinopathies-Membrane associated phenomena
in SS disease.
POIHl.16833.04 0009 (HEP) KELLER, KENNETH H. Hemoglobin and red cell
system in hemoglobinopathies-Rheological studies of sickled cells
(human).
P0IHH6833-04 0011 (HEP) WHITE, JAMES G. Hemoglobin and red cell system
in hemoglobmopathics-Relationship between hemoglobin and RBC
membrane in sickling cells (human, rats)
POIHl-1 6833-04 0014 (HEP) JACOB, HARRY S. Hemoglobin and red cell system
in hemoglobinopathies-Erythrocyte membrane damage in Mb SS dis-
ease (human)
POIHl-1 6833-04 0015 (HEP) MOSCOWITZ, ALBERT. Hemoglobin and red cell
system in htmoglobinopathies-Stereochcmistry of hemoglobins from
magnetic circular dichroism (human)
PCI Hl.l 6833.04 0016 (HEP) EATON, JOHN W. Hemoglobin and red cell system
in hemoglobinopathies-Calcium-indiced membrane damage in Hb SS
disease (human, animals).
POIHl-16833-04 0017 (HEP) KRIVIT, WILLIAM. Hemoglobin and red cell system
in hemoglobinopathies-Sulfhydryl group blockade antisickling effect
(human).
P01HL.168S1-04 (HEP) CHIEN, SHU, COLUMBIA UNIVERSITY. 630 WEST 168TH
STREET, NEW YORK. N Y. Human red cell membrane in health and
disease.
POlHl.16851-04 0001 (HEP) CHIEN, SHU. Human red cell membrane in health
D«f... ,x«,. ""'' "'sease-'Rheology of erythrocyte membrane (human, amphiuma)
P01H1.168S1-04 0003 (HEP) SKAIAK, RICHARD. Human red cell membrane in
health and disease-Modeling membrane mechanics and blood rheolo-
gy.
P01HH68SI.04 0005 (HEP) BERTLES, JOHN F. Human red cell membrane in
health and disease-Relation of hemoglobin species to membrane pro-
perties (human).
POIHl.16851-04 0006 (HEP) SCHACHTER, DAVID. Human red cell membrane in
health and disease-Hexose transport and erythrocyte membrane
proteins (human).
POIHL-1 685 1-04 0008 (HEP) JAN, KUNG-MING. Human red cell membrane in
^"'' ""'sease -Force balance in red cell interactions (human)
P01HL-16851-04 0009 (HEP) CHIEN, SHU. Human red cell membrane in health
and disease-Blood cell properties in circulatory regulation (does rab-
bits), '
POIHL-1 685 1-04 0010 (HEP) CHIEN, SHU. Human red cell membrane In health
and disease-Core facility-Hematology clinic
P01HL-16851-04 0011 (HEP) LEE, MARY M L. Human red cell membrane in
health and disease-Ultrastructure laboratory-Core facility
P01HL-16851-04 0012 (HEP) SCHUESSLER, GEORGE. Human red cell mem-
brane in health and disease-Computer unit -Core facility
HOIHl-16855.03 (AFY) HEMMINGSEN, EDVARD A, UNIV OF CALIFORNIA SAN
DIEGO. SCRIPPS INST OF OCEANOGRAPHY. LA JOLU, CALIF. Cavilation
in biological systems (microorganisms, animals)
R01HL- 16860-05 (BBCB) LANG, L GEORGE, PENNSYLVANIA STATE UNIVERSITY
DEPARTMENT OF PHYSICS. UNIVERSITY PARK, PA. Mossbauer studies
of respiratory hemoproteins.
ROlHl-16872-04 (HEM) HOYER, LEON W, UNIVERSITY OF CONNECTICUT DEPT OF
MEDICINE, FARMINGTON, CONN. Antihemophilic factor (human)
POlHL-16878-05 (HEP) ZECHMAN, FRED W, UNIVERSITY OF KENTUCKY DEPT OF
PHYSIO & BIOPHSICS, LEXINGTON, KY. Control of ventilation' in health
and disease.
POlHL-16878-05 0001 (HEP) BURKI, N K. Control of ventilation in health and
disease-Ability of asthmatics to detect added resistive and elastic
loads.
P01HL. 16878-05 0003 (HEP) FRAZIER, DONALD T. Control of ventilation in
health and disease -Brain stem respiratory neurons in response
mechanical/chemical loading (animal)
POlHL-16878-05 0004 (HEP) BOYARSKY, LOUIS L. Control of ventilation in
„ ''^a'"' and disease -Neurotransmitters in the respiratory system (cats)
POlHl-16878-05 0005 (HEP) ZECHMAN, FRED W. Control of ventilation in
health and disease-Program core.
R01Hl.16891.05 (BBCA) BUCCI, CLARA F, UNIVERSITY OF MARYUND 660 WEST
REDWOOD STREET, BALTIMORE. MD. The folding of hemoglobin
R01 HI. 1 690 LOS (CVA) HORAN, LEO G, UNIVERSITY OF LOUISVILLE HEALTH
SCIENCES CENTER, LOUISVILLE, KY. Multipolar linkage between heart
geometry and surface (human, dogs).
ROl HI. 16904-03 (PBC) FULLER, GEORGE C, UNIVERSITY OF RHODE ISLAND
PHARMACOLOGY & TOXICOLOGY DEPT, KINGSTON, R I. Regulation of
smooth muscle cells in arteriosclerosis (rabbit aorta)
R01HL.16908.04 (TEC) WHIPPLE, IRA T, CHICAGO HEALTH RESEARCH FDN CIVIC
CENTER, ROOM LL-139, CHICAGO, ILL. Myocardial function, risk factors
and future CHD (men).
ROl Hl-1 6909.04 (TEC) TAYLOR, HENRY I, UNIVERSITY OF MINNESOTA, STADIUM
GATE 27, MINNEAPOLIS, MINN. Myocardial function, risk factors and
future CHD (men).
550
POIHl
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R01HL.
R01HL
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ROIHl-
R01HL.
ROIHL-
ROIHl-
ROIHL
R01HL.
ROIHl-
R25HL-
ROIHl.
ROl HI.
ROIHL-
R01HL
R01HL
P60HL-
P60HL-
P60HL
P60HL-
P60HI-
P60HI-
P60HL
P60HL
P60HL.
P60HL
P60HI.
16910.05 (HEP) SCHER, ALLEN M, UNIVERSITY OF WASHINGTON, SCHOOL
OF MEDICINE, SEATTLE. WASH. Regulation of the peripheral circula-
tion.
16910-05 0001 (HEP) WIEOERHIEUM, CURT A. Regulation of the
peripheral circulation -Quantitative studies of microcirculatory control
(bats).
■16910-05 0002 (HEP) FEIGL, ERIC O. Regulation of the peripheral circula-
tion-Coronary circulation (dogs)
•16910-05 0005 (HEP) SCHER, ALLEN M. Regulation of the peripheral cir-
culation-Control of circulation by barorecepfor and chemoreceptor
reflexes (dog, monkey).
16910-05 0006 (HEP) ROWELl, lORING B. Regulation of the peripheral
circulation-Regulation of blood flow distribution (baboons dogs)
16910-05 0007 (HEP) SMITH, ORVIILE A. Regulation of the peripheral
circulation-CNS-Behavioral influences on circulation (baboons)
-16910-05 0008 (HEP) BROWN, ARTHUR c. Regulation of the peripheral
circulation-Circulation to bone (dogs, baboons).
-16916-04 (CVA) MARSHALL, BRYAN E, UNIVERSITY OF PENNSYLVANIA
3400 SPRUCE STREET, PHILADELPHIA, PA. The role of albumins in
lung water accumulation.
■16916-04 0001 (CVA) MARSHALL, BRYAN E. The role of albumins in
lung water accumulation-Capillary permeability (dogs human)
16916.04 0002 (CVA) MARSHALL, BRYAN E. The role of albumins in
lung water accumulation -Lung water balance-Forces, models and al-
bumin concentrations (rabbits, dogs)
16916-04 0011 (CVA) MARSHALL, BRYAN E. The role of albumins in
lung water accumulation-Whole body distribution and exchange of al-
bumin (rabbits, human, monkeys).
16918-05 (CVB) BAXTER, JOHN D, UNIVERSITY OF CALIFORNIA METABOL-
IC RES UNIT, 1143 HSW, SAN FRANCISCO, CALIF. Role of steroids in
hypertension (human).
■16919-05 (HEM) DAVIE, EARL W, UNIVERSITY OF WASHINGTON DEPT OF
BIOCHEM. SJ-70. SEATTLE. WASH. Proteins of blood coagulation
(human, bovine).
16920-02 (PC) KALNITSKY, GEORGE, UNIVERSITY OF IOWA, BIOCHEMIS-
TRY DEPARTMENT, IOWA CITY, IOWA. Proteases in normal and immu-
nologically injured lung (guinea pigs, rabbits).
16921-05 (SGYB) ANDRADE, JOSEPH D, UNIVERSITY OF UTAH COLLEGE
OF ENGINEERING, SALT LAKE CITY, UTAH. Synthetic hydrogels as blood
tolerable materials.
16927.05 (BBCB) BUNN, H FRANKLIN, AFFILIATED HOSPITAL CTR INC
721 HUNTINGTON AVENUE. BOSTON, MASS. Structure and function of
normal and abnormal hemoglobin (human).
16931-04 (HEM) BARTIETT, GRANT R, UB FOR COMPARATIVE BIOCHEM
4620 SANTA FE STREET, SAN DIEGO, CALIF. Red cell storage and
transfusion (human, animals).
16935-05 (SGYB) DECK, J DAVID, UNIVERSITY OF VIRGINIA 1300 JEFFER-
SON PARK AVENUE, CHARLOHESVILLE, VA. Tissue organization and
turnover in the semilunar valve (dogs, rats)
16938-05 (SGYB) ALFREY, CLARENCE P, JR, METHODIST HOSPITAL 6516
BERTNER. HOUSTON, TEX. Effect of physical forces on blood '(dogs
human). ^
16952.05 (PTHA) MAJNO, GUIDO, UNIVERSITY OF MASSACHUSEnS 55
UKE AVE NORTH, WORCESTER, MASS. Cardiovascular pathology (rats
rabbits). '
16955.05 (HEM) DANISHEFSKY, ISIDORE, NEW YORK MEDICAL COLLEGE
BIOCHEMISTRY DEPARTMENT, VALHALLA, N Y. Heparin, blood coagula^
fion and lipid metabolism (human).
17056-01 (SRC) POWERS, MARJORIE J, UNIVERSITY OF ROCHESTER 260
CRITTENDEN BOULEVARD. ROCHESTER, N Y. Improving patient com
pliance through nursing action.
17080-05 (MBY) PALADE, GEORGE E, YALE UNIVERSITY. 333 CEDAR
STREET, NEW HAVEN, CONN. Localization of pore systems in capilla^
walls (rats, mice, rabbits).
"°""°*Jv*^T,*o' ^PNGNECKER, DAVID E, UNIV OF VIRGINIA MED CTR.
BOX 238 CHARLOHESVILLE, VA. Anesthetics and microvascular
response to hemorrhage (rats).
17194-03 (PC) GUSER, CHARLES B, INSTITUTES OF MEDICAL SCIENCES
POST OFFICE BOX 7999. SAN FRANCISCO. CALIF. Comparison of two
inherited forms of alpha-1-antitiypsin (human)
.17243-05 (CVB) SKEGGS, LEONARD T, VETERAND ADMINISTRATION HOSP.
10701 EAST BOULEVARD, CLEVEUiND, OHIO. Cause of chronic expert:
mental renal hypertension (dogs, rabbits)
17246-03 (CVA) AUCHINCIOSS, J HOWIAND, JR, STATE UNIVERSITY
HOSPITAL, 750 EAST ADAMS STREET, SYRACUSE. N Y. Oxygen uptke
at one minute of exercise (human).
17265-04 (SRC) DONOHUE, DENNIS M, PUGET SOUND BLOOD CENTER
Lpport "*°'^°'^' ^""'■^' ^*^"- '='""'"""'»y "'""O ^«°"^« "nte;
17265-04 0001 (SRC) CRITCHIOW, CATHY. Community blood resource
center support-Demonstration and evaluation
17265-04 0002 (SRC) COUNTS, RICHARD B. Community blood resource
center support-Research -Human factor VIII
""'■"ir" *^'"'' THOMPSON. ARTHUR R. Community blood
resource center support-Research-Human factor IX-Role in intrinsic
clotting (also baboons, dogs)
17265-04 0006 (SRC) SLICHTER, SHERRIU J. Community blood resource
center support-Research-Evaluation of platelet transfusions (human,
17265-04 0007 (SRC) SIMON, TOBY I. Community blood resource center
support-Research -Massive transfusion and trauma (human)
17265-04 0008 (SRC) GIBIETT, ElOISE R. Community blood resource
center support-Research-Blood genetic markers as biological probes
inu m 3 nj.
17265.04 0009 (SRC) PRICE, THOMAS H. Community blood resource
center support -Research-Developing granulocyte transfusion therapy
(human, rabbit).
17265.04 0010 (SRC) HILUVIAN, ROBERT S. Community blood resource
center support-Blood resources educational program
17269-04 (SRC) DE BAKEY, MICHAEL E, BAYLOR COLLEGE OF MEDICINE
6516 BERTNER BLVD. HOUSTON, TEX. National heart and blood vessel
research and demonstration center
17269-04 0001 (SRC) TITUS, JACK L. National heart and blood vessel
research and demonstration center-Atherosclerosis-Arterial pathology
and plasma lipids (human)
551
PROJECT NUMBER AND INVESTIGATOR ADDRESS
P60HI-17369-04 0003 (SRC) WAKIl. SAUH J. National hiart and blood vessel
leseaich and demonsltalion center Alhetosclerosis fatty acid
metabolism in caidiovasculaf tissue (human, chicken)
MOHL- 17269-04 0004 (SRC) TITUS, JACK I. National heart and blood vessel
research and demonstration center Atherosclerosis-Clinical sur(ic8l
aspects (human)
P60HI- 17369-04 0007 (SRC) TITUS, JACK I. National heart and blood vessel
research and demonstration center Correlative studies ot experimental
myocardial ischemia (dog)
P60HI- 17269-04 0009 (SRC) MORRISETT, JOEL D. National heart and blood ves
sel research and demonstration center Physical methods laboratory
(high density lipoproteins)
P60HI- 17269-04 0011 (SRC) JACKSON. RICHARD I. National heart and blood
vessel research and demonstration center-lipoprotein structure
laboratory (human)
P60HL- 17269-04 0013 (SRC) SPARROW, JAMES T. National heart and blood
vessel research and demonstration center-Peptide synthesis laboratory
(human)
P60HL- 17269-04 0014 (SRC) POWNAIL, HENRY J. National heart and blood
vessel research and demonstration center Physio-chemical nature of
lipid deposits in arterial wall (human)
P60HL- 17269-04 0015 (SRC) SMITH, LOUIS C. National heart and blood vessel
research and demonstration center -Lipoprotein metabolism laboratory
(human).
P60HI- 17269-04 0016 (SRC) HORNING, EVAN C. National heart and blood ves-
sel research and demonstration center- New analytical methodology for
atherosclerosis studies.
P60HL- 17269-04 0017 (SRC) SCHWARTZ, ARNOLD. National heart and blood
vessel research and demonstration center-Cell membrane (dogs, rab-
bits)
P60HL-17269-04 0018 (SRC) WOOD, JEANIE M. National heart and blood ves-
sel research and demonstration center -Mitochondria and energetics
(rabbits, dogs).
P60HL- 17269-04 0019 (SRC) ENTMAN, MARK L. National heart and blood ves-
sel research and demonstration center-Sarcoplasmic reticulum (dog.
rabbit, hamster, cat).
P60HI- 1 7269-04 0020 (SRC) GILLETTE, PAUL C. National heart and blood vessel
research and demonstration center -Nucleic acid and protein metabol-
ism in growth and development of heart (rat).
P60HL-1 7269-04 0021 (SRC) GOLDSTEIN, MARGARET A. National heart and
blood vessel research and demonstration center-Growth and develop-
ment of heart-Ultrastructure (dog. guinea pig. rat. cat).
P60HL-1 7269-04 0022 (SRC) WALLICK, EARL T. National heart and blood vessel
research and demonstration center-Medicinal chemistry (rabbit, dog.
guinea pig).
P60HI-1 7269-04 0023 (SRC) MCINTOSH, HENRY D. National heart and blood
vessel research and demonstration center -Cardiovascular pharmacolo-
gy-Ischemia, shock and heart failure (dog. cat. rat).
P60HL- 1 7269-04 0024 (SRC) LEWIS, ROBERT M. National heart and blood vessel
research and demonstration center-Section of experimental car-
diovascular surgery-Core facility.
P60HL-1 7269-04 0026 (SRC) MCINTOSH, HENRY D. National heart and blood
vessel research and demonstration center-Dynamics of ischemic heart
disease (human, dog).
P60HL-1 7269-04 0027 (SRC) WRIGHT, KINSMAN E. National heart and blood
vessel research and demonstration center-Non-invasive evaluation of
cardiac function-lschemic heart disease (human, dog).
P60HL-1 7269-04 0029 (SRC) DEBAKEY, MICHAEL E. National heart and blood
vessel research and demonstration center-Clinical application of cir-
culatory assistance (human).
P60HL- 17269-04 0030 (SRC) DEBAKEY, MICHAEL E. National heart and blood
vessel research and demonstration center-Cardiovascular engineering
laboratories (human).
P60HL- 17269-04 0031 (SRC) GLAESER, DONALD H. National heart and blood
vessel research and demonstration center-Computer-assisted data
acquisition and clinical data processing.
P60HL- 17269-04 0032 (SRC) DEBAKEY, MICHAEL E. National heart and blood
vessel research and demonstration center-Clinical circulatory assist
device fabrication.
P60HI- 1 7269-04 0033 (SRC) ROSSEN, ROGER D. National heart and blood ves-
sel research and demonstration center-Autoallergic response in car-
diomyopathy, atherosclerosis, rheumatic heart disease.
P60HI- 17269-04 0034 (SRC) TRENTIN, JOHN J. National heart and blood vessel
research and demonstration center-lmmunologic enhancement of car-
diac allografts (mice).
P60HL- 17269-04 0035 (SRC) MEINICK, JOSEPH I. National heart and blood
vessel research and demonstration center-Blood resources-Research
program in viral hepatitis (human).
P60HL-1 7269-04 0036 (SRC) WEAVER, FRANK J. National heart and blood ves
sel research and demonstration center-Public education.
P60HI- 17269-04 0037 (SRC) ROUSH, ROBERT E. National heart and blood ves-
sel research and demonstration center-Secondary and university edu-
cation.
P60HI- 17269-04 0038 (SRC) TAYLOR, FRED M. National heart and blood vessel
research and demonstration center-Continuing education.
P60HI- 17269-04 0039 (SRC) VALLBONA, CARLOS. National heart and blood
vessel research and demonstration center-Health care services to pa-
tients in neighborhood clinics.
P60HL-1 7269-04 0042 (SRC) EVANS, RICHARD I. National heart and blood ves-
sel research and demonstration cenfer-Social-psychological smoking
deterrents in schools.
P60HI-1 7269-04 0043 (SRC) FOREYT, JOHN P. National heart and blood vessel
research and demonstration center-Dietary modification-Effect on car-
diovascular risk parameters (human).
P60HL-1 7269-04 0045 (SRC) SMITH, LOUIS C. National heart and blood vessel
research and demonstration center-Regulation of lipogenesis in hyper-
lipoproteinemia (human, tissue culture).
P60HL-1 7269-04 0046 (SRC) MORRISETT, JOEL D. National heart and blood ves-
sel research and demonstration center-Nuclear magnetic resonance
laboratory.
P60HI- 17269-04 0047 (SRC) RUSSELL, MICHAEL I. National heart and blood
vessel research and demonstration center-Evaluation of competency-
based educational model.
P60HL- 1 7369-04 0048 (SRC) HOFF, HENRY F. National heart and blood venel
research and demonstration center Atheroiclerosit tipoproteinj and
the arterial wall (human)
P60HI-1 7292-04 (SRC) CRAIGHEAD, JOHN E, UNIVERSITY OF VERMON). GIVEN
BUILDINt;. ROOM C331. BORIINGtON. VI Vermont Lung Center
P60HI-1 7292-04 0003 (SRC) CRAIGHEAD, JOHN E. Vermont lung Center
Subclinical pulmonary disease in a rural environment (human)
P60HI-1 7292-04 0005 (SRC) CRAIGHEAD. JOHN E. Vermont lung Center
Mineral pneumoconioses Pathogenesis and pathology (human)
P60HL-1 7292-04 0008 (SRC) ALPERT, NORMAN R. Vermont Lung Center
Respiratory physiology leaching, learning and auditing problem solv
ing skills
P60HL-1 7292-04 0009 (SRC) ALLEN, SINCLAIR T, JR. Vermont lung Center
Controlled clinical trials on a clinical core unit (human)
P60HL- 17292-04 0013 (SRC) ALIEN, SINCLAIR T, JR. Vermont Lung Center Re
gional management of respiratory disease program
P60HI-1 7292-04 0018 (SRC) SLACK, HUBERT R. Vermont Lung Center Group pa-
tient education Breathing workshop project
P60HL- 17292-04 0020 (SRC) SLACK, HUBERT R. Vermont Lung Center Mass in
formation Education project
P60HI-1 7292-04 0021 (SRC) SLACK, HUBERT R. Vermont lung Center School
lung education project
P60HL-1 7292-04 0023 (SRC) DORSEY, FRANK C. Vermont Lung Center -Health
information resources
P60HL-1 7292-04 0024 (SRC) HOLMES DAVID R. Vermont Lung Center -Education
and media resources unit
P60HI-1 7292-04 0029 (SRC) CHASE, CHRISTOPHER R. Vermont Lung Center
Computer-assisted preoperative evaluation (human).
P60HI-1 7292-04 0030 (SRC) ALLEN, SINCLAIR T, JR. Vermont Lung Center
Hospital treatment of pneumonia.
P60HL-1 7292-04 0031 (SRC) ALLEN, SINCLAIR T, JR. Vermont Lung Center Re
gional respiratory computer network.
ROIHl-1 73 14-04 (CVA) KAFER, ENID R, UNIVERSITY OF NORTH CAROLINA. OE
PARTMENT OF ANESTHESIOLOGY. CHAPEL HILL. N C Effects of
anesthesia and loading on respiration (human, cats).
ROIHl-1 7322-04 (CVA) SOUHRADA, JOSEPH F, NATL JEWISH HOSP & RES
CENTER, 3800 E COLFAX AVENUE. DENVER. COLO Functional charac-
teristics of smooth muscle isolated from lung (animals).
ROIHL-17332-04 (GMA) RODGERS, JOHN B, JR, ALBANY MEDICAL COLLEGE. 47
NEW SCOTUND AVENUE. ALBANY. N Y Use of the gut for therapy of
coronary artery disease (mammals).
ROIHL-1 7335-05 (CVB) HALPERN, WILLIAM, UNIVERSITY OF VERMONT. PHYSIOLO-
GY & BIOPHYSICS DEPT. BURLINGTON. VT. Contractile properties of
hypertensive arterioles (rats).
ROIHL-1 7341 -03 (MCHA) SCHLESSINGER, RICHARD H, UNIVERSITY OF
ROCHESTER. DEPARTMENT OF CHEMISTRY. ROCHESTER. N Y. Practical
total synthesis of prostaglandins.
ROlHL-1 7352-03 (AFY) FRANKEL, HARRY M, RUTGERS UNIVERSITY, DEPARTMENT
OF PHYSIOLOGY. NEW BRUNSWICK. N J. Physiological regulation during
chronic hyperthermia (sheep).
ROlHL-1 7355-04 (CVA) MALIK, ASRAR B, ALBANY MEDICAL COLL-UNION UNIV. 47
NEW SCOTLAND AVENUE. ALBANY, N Y. Pulmonary/ vascular adjust-
ments in circulatory collapse (dogs, rats).
ROIHL-1 7358-04 (SGYA) SULLIVAN, STUART F. UNIVERSITY OF CALIFORNIA. DE
PARTMENT OF ANESTHESIOLOGY. LOS ANGELES. CALIF. Ventilatory ad-
justments for optimal oxygenation (dogs. rats).
ROIHL-1 7364-04 (CVB) LUETSCHER, JOHN A, JR, STANFORD UNIVERSITY, STAN
FORD MEDICAL CENTER M-204 , STANFORD, CALIF. 'Big renin'-
Biochemical and clinical studies (human).
ROIHL-1 7366-05 (CVB) JOHNSON, JOSEPH A, UNIVERSITY OF MISSOURI DEPT
OF PHYSIOLOGY, COLUMBIA. MO. Mechanisms in the production of
renal hypertension (rabbits, dogs).
ROIHL-1 7367-05 (HED) KRALIOS, FANY A, UNIVERSITY OF UTAH, MEDICAL
CENTER. BLDG 100. SALT LAKE CITY. UTAH. Functional sympathetic
development in neonatal hearts (dogs, human).
ROIHL-17369-04 (SGYB) FUCHS, JAMES C, DUKE UNIVERSITY. POST OFFICE BOX
3351. DURHAM. N C. Arterial bypass surgery-Structure and metabol-
ism (monkeys).
ROlHL-1 7370-03 (NEUB) TOWNSEL, JAMES G, MEHARRY MEDICAL COLLEGE.
1005 18TH AVENUE NORTH, NASHVILLE, TENN. Synaptic chemistry and
cardioregulation in Limulus.
R01HL-17371-0S (MET) BROCKMAN, HOWARD L, JR, UNIVERSITY OF MIN
NESOTA, 801 16TH AVENUE, N E, AUSTIN. MINN. Regualtion of choles-
teryl ester levels in the aorta (swine).
ROIHl-1 7372-03 (BIO) SEYMOUR, F R, BAYLOR COLLEGE OF MEDICINE. 1200
MOURSUND AVENUE. HOUSTON. TEX. Adenine nucleotide maintenance
in the ischemic heart (rats).
ROIHL-1 7376-04 (CVA) GOLDSTEIN, MARGARET A, BAYLOR COLLEGE OF
MEDICINE, 1200 MOURSUND AVENUE. HOUSTON. TEX. Analysis of Z
bands in heart by optical diffraction (mammals).
P01HL-1 7382-05 (HEP) AUSTEN, KARL F, ROBERT B BRIGHAM HOSP. 125 PARKER
HILL AVE. BOSTON, MASS. Chemical mediators of acute pulmonary
disorders.
POlHL-1 7382-05 0001 (HEP) MCFADDEN, REGIS. Chemical mediators of acute
pulmonary disorders-Chemical mediators and respiratory mechanics
in humans.
POlHL-1 7382-05 0002 (HEP) DRAZEN, JEFFREY. Chemical mediators of acute
pulmonary disorders -Chemical mediators and respiratory mechanics
in guinea pigs.
P01HL-1 7382-05 0003 (HEP) AUSTEN, K FRANK. Chemical mediators of acute
pulmonary disorders-Chemical mediators relevant to allergic reactions
(human, guinea pigs).
ROlHL-17401-03 (PHRA) BUCKLEY, JOSEPH P, UNIVERSITY OF HOUSTON, 4800
CALHOUN BLVD. HOUSTON. TEX. Mechanisms in angiotensin induced
hypertension (cats. dogs).
ROIHl-1 7402-04 (SSS) SCHIFFMAN, SANDRA, UNIV OF SOUTHERN CALIFORNIA.
2025 ZONAL AVENUE. LOS ANGELES, CALIF. Mechanism of contact ac-
tivation of intrinsic clotting (human).
ROIHL-1 7403-03 (CVA) LIANG, CHANG-SENG, BOSTON UNIVERSITY, 80 EAST
CONCORD STREET, BOSTON, MASS. Metabolic control of cardiac output
(dogs).
ROIHL-1 7404-05 (VR) WOODRUFF, JACK F, CORNELL UNIVERSITY, 1300 YORK
AVENUE, NEW YORK. N Y. Immunologic mechanisms in heart disease
(mice).
ROIHl-
R01HL-
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PROJECT NUMBER AND INVESTrGATOR ADDRESS
RO I HI- 17407-05 (AFY) DU BOIS, ARTHUR B, JOHN B PIERCE FOUNDATION 290
CONGRESS AVENUE. NEW HAVEN, CONN. Peripheral circulation' and
fluid balance (fish, mammals, human).
17408-03 (CVB) KRON, REUBEN E, UNIVERSITY OF PENNSYLVANIA 202
PIERSOL BUILDING. PHIUOELPHIA. PA Fresh blood rheology-Relation
to cardiovascular risk (human).
17411-04 (BBCB) BRANTON, DANIEL, HARVARD UNIVERSITY. 16 DIVINITY
STREET. CAMBRIDGE. MASS. Molecular studies of red blood cell spec-
trin (human).
■17417-05 (SRC) VEITH, FRANK J, MONTEFIORE HOSP & MEDICAL CTR 111
EAST 210TH STREET. NEW YORK. N Y. Experimental lung transplanta-
tion.
17417-05 0001 (SRC) NORIN, ALLEN J. Experimental lung transplanta
tion-Mechanisms and mediators of lung allograft rejection (dogs
mice).
17417-05 0003 (SRC) EMESON, EUGENE. Experimental lung transplanta-
tion-Methods for detecting lung allograft rejection (dogs).
17417-05 0004 (SRC) NORIN, ALLEN J. Experimental lung transplanta-
tion-Methods for suppressing lung allograft rejection (dogs, mice)
17417-05 0005 (SRC) VEITH, FRANK J. Experimental lung transplanta-
tion-Lung transplantation in bilateral emphysema (dogs)
17417-05 0006 (SRC) VEITH, FRANK J. Experimental lung transplanta-
tion-Bronchial anastomotic problems and increases donor lung availa-
bility (dog),
17419-04 (HEPB) MOSESSON, MICHAEL W, S U N Y OOWNSTATE MED
CTR. 450 CURKSON AVENUE. BROOKLYN. N Y. Studies on
mechanisms of hemostasis.
17419-04 0001 (HEPB) MOSESSON, MICHAEL W. Studies on
mechanisms of hemostasis-Structure and metabolism of fibrinogen
(human).
17419-04 0003 (HEPB) GALANAKIS, DENNIS. Studies on mechanisms
of hemostasis-Characterization of fibrinogen (human).
17419-04 0006 (HEPB) PINDYCK, JOHANNA. Studies on mechanisms of
hemostasis-Effect of hormones, drugs and other agents on fibrinogen
synthesis (chick).
17419-04 0007 (HEPB) TOONEY, NANCY M. Studies on mechanisms of
hemostasis-Structural analysis of ordered forms of fibrinogen
(human, cattle).
-17421-05 (HEP) JOHNSON, PAUL C, UNIVERSITY OF ARIZONA. PHYSIOLO-
GY DEPT. TUCSON, ARIZ. Regulation and exchange in the microcircula-
tion.
■ 17421-05 0001 (HEP) GROSS, JOSEPH F. Regulation and exchange in
the microcirculation-Mass transfer and microcirculatory function
(rats).
■17421-05 0002 (HEP) GROSS, JOSEPH F. Regulation and exchange in
the microcirculation-Metabolic and myogenic blood flow regulation in
microcirculation (animals).
17421-05 0003 (HEP) GORE, ROBERT W. Regulation and exchange in the
microcirculation-Transcapillary fluid exchange in rat intestinal
muscle, mucosa, and mesentery.
17421-05 0004 (HEP) JOHNSON, PAUL C. Regulation and exchange in
the microcirculation-Localization of flow regulation in the microcircu-
lation (cats, human).
17421-05 0006 (HEP) JOHNSON, PAUL C. Regulation and exchange in
the microcirculation-Core facilities -Optical instrumentation facility
17421-05 0007 (HEP) INTAGLIETTA, MARCOS. Regulation and exchange
m the microcirculation-Core facilitles-Fluorometric measurement
methods for microcirculation.
-17430-05 (HEP) BOVKIE, E J, MAYO FOUNDATION, 200 FIRST ST SOUTHWEST
ROCHESTER, MINN. Control of coagulation.
-17430-05 0001 (HEP) BOWIE, E J WALTER. Control of coagulation -Por-
cine von Willebrand's disease.
■ 17430-05 0002 (HEP) FASS, DAVID N. Control of coagulation- Isolation of
ristocetin -von Willebrand factor (swine).
■17430-05 0005 (HEP) MANN, KENNETH G. Control of coagulation The
activation of prothrombin (human, cattle, dogs).
•17430-05 0006 (HEP) OWEN, CHARLES A. Control of coagulation-Activa-
tion fragments of prothrombin in vitro and in vivo (human, dogs cat-
tle).
17430-05 0007 (HEP) DiDlSHElM, PAUL. Control of coagulation-Platelet
adhesion, aggregation, ultrastructure in flowing blood (human,
animals).
17430-05 0008 (HEP) FASS, DAVID N. Control of coagulation -Cultures of
von Willebrand endothelial cells (pigs).
-17437-03 (SGYB) MC INTIRE, LARRY V, RICE UNIVERSITY, P 0 BOX 1892.
HOUSTON. TEX. 'Perfusion lung-Role of traumatized leukocytes (dogs!
human),
-17451-05 (PHRA) VASSALLE, MARIO, S U N Y ■ DOWNSTATE MED CTR
450 CURKSON AVENUE, BROOKLYN, N Y. Digitalis effects on cardiac
automaticity mechanisms.
17452-04 (PHRA) KATZUNG, BERTRAM G, UNIVERSITY OF CALIFORNIA
DEPT OF PHARMACOLOGY. SAN FRANCISCO, CALIF. Depolarization in-
duced cardiac automaticity (human, animals).
■17458-04 (CVB) ALEXANDER, EDWARD A, BOSTON CITY HOSPITAL 818
HARRISON AVENUE, BOSTON, MASS, Renal control of sodium excretion
(rats),
■17459-03 (CVB) VATNER, STEPHEN F, PETER BENT BRIGHAM HOSPITAL
721 HUNTINGTON AVENUE, BOSTON, MASS. Myocardial ischemia
(dogs)
17462-03 (PC) SWEELEY, CHARLES C, MICHIGAN STATE UNIVERSITY DE-
PARTMENT OF BIOCHEMISTRY, EAST LANSING, MICH. Role of glycos-
phingolipids in platelet aggregation (rats, human, dogs),
17463-03 (MET) SHORE, VIRGIE G, UNIVERSITY OF CALIFORNIA, BIOMEDI-
CAL DIVISION, L-523, LIVERMORE, CALIF, Composition and structure of
plasma lipoproteins (human, rabbits).
17465-04 (GEN) ROWLEY, PETER T, UNIVERSITY OF ROCHESTER, 601 ELM-
WOOD AVENUE, ROCHESTER, N Y. Beta-thalassemia screening and
genetic counseling.
17479-04 (SGYB) MC CONN, RITA, ALBERT EINSTEIN COLLEGE OF MED
1300 MORRIS PARK AVENUE. BRONX, N Y Blood storage-The produc-
tion of cardiotoxic material (dogs, human, swine).
17487-04 (PHRA) WEINSHILBOUM, RICHARD M, MAYO FOUNDATION
200 FIRST STREET SOUTHWEST. ROCHESTER. MINN. Adrenergic'
vasoregulatpon interactions in hypertension (human).
552
ROIHL-
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POIHl-
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ROIHL-
ROIHL-
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ROIHL-
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ROIHL.
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ROIHL-
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ROIHL
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ROIHL.
ROIHL
ROIHL
P50HL.
P50HL-
P50HL-
P50HL
PSOHL
17494-07 (BBCA) SCHUSTER, TODD M, UNIVERSITY OF CONNECTICUT,
BOX U-125, STORRS. CONN. Mechanism of liqand binding to
hemoglobin (human).
17503-03 (AFY) D'HOUST, BRIAN G, VIRGINIA MASON RES CENTER. 1000
SENECA STREET, SEAHLE, WASH. Vascular bubbles in decompression
sickness (minipig, dog. goat).
17513-04 (HEM) HANDIN, ROBERT I, PETER BENT BRIGHAM HOSPITAL
721 HUNTINGTON AVENUE, BOSTON, MASS. Role of PF-4 in detecting
and promoting thrombosis (human, primates).
■17516-04 (CVB) RAMWELL. PETER W, GEORGETOWN UNIVERSITY
PHYSIOLOGY & BIOPHYSICS DEPT. WASHINGTON, D C. Role of an-
drogen as a risk factor in atherogenesis (human, animals).
■17517-03 (CVA) GOLDSTICK, THOMAS K, NORTHWESTERN UNIVERSITY
CHEMICAL ENGINEERING DEPT, EVANSTON. ILL. Arterial wall oxygen
transport in atherosclerosis (rabbits, dogs).
■17525-03 (MBV) MICHAELI, DOV, UNIVERSITY OF CALIFORNIA, DEPART-
MENT OF BIOCHEM & BIOPHY, SAN FRANCISCO. CALIF. Molecular basis
of collagen-platelet interaction (human, rat).
17532-04 (CVB) SELVESTER, RONALD H, 7413 GOLONDRINAS STREET,
DOWNEY, CALIF. Infarct size-ECG. angio, path, correlation in dogs.
17543-03 (PTHA) COHEN. DAVID, MASSACHUSEHS INST OF TECH. 170
ALBANY STREET, CAMBRIDGE, MASS. Magnetic tracers for diagnosis of
lung disease
17543-03 0001 (PTHA) GAENSLER, EDWARD A. Magnetic tracers for
diagnosis of lung disease-Chronic, interstitial lung disease (human,
rabbits).
■ 17543-03 0002 (PTHA) COHEN, DAVID. Magnetic tracers for diagnosis
of lung disease -Magnetite as an index of asbestos exposure (human)
-17543-03 0003 (PTHA) COHEN, DAVID. Magnetic tracers (or diagnosis
of lung disease-Occupationally accumulated magnetite for diagnosis
of lung disease (human),
17543-03 0004 (PTHA) BRAIN, JOSEPH D. Magnetic tracers for diagno-
sis of lung disease-Magnetite retention, distribution, relaxation rate,
viscosity (rabbits).
17551-04 (MBY) GOLDBERG, BURTON 0, NEW YORK UNIVERSITY 550
FIRST AVENUE, NEW YORK, N Y. Biosynthesis and metabolism of
procollagen (human, monkeys, mice).
17552-03 (PC) BENESCH, RUTH E, COLUMBIA UNIVERSITY. 630 WEST
168TH STREET. NEW YORK, N Y. Sickling inhibition by chemical
modification of hemoglobin (human),
17555-05 (CVB) MARKS, BERNARD H, WAYNE STATE UNIVERSITY 540
EAST CANFIELD AVENUE, DETROIT, MICH. Distribution and metabolism
of labeled digitaloids (dogs, guinea pigs).
17559-03 (BBCB) HARTZELL, CHARLES R, PENNSYLVANIA STATE UNIVERSI-
TY, 108 ALTHOUSE UBORATORY, UNIVERSITY PARK, PA. Structural elu-
cidation of heart cytochrome-C oxidase.
17564-03 (NTN) CEVALLOS, WILLIAM H, LANKENAU HOSPITAL UN-
CASTER & CITY LINE AVENUES . PHIUDELPHIA, PA. Unsaturated fats-
Mode of hypocholesterolemic action (minipig).
17567-03 (BBCA) HARVIE, NANCY R, UNIVERSITY OF MICHIGAN 2200
BONISTEEL BOULEVARD. ANN ARBOR, MICH. Lipoprotein-cytolytic toxin
interaction (Staphylococcus aureus, mammals, human).
17571-03 (BBCB) EISENSTADT, MAURICE, ALBERT EINSTEIN COLLEGE OF
MED, 1300 MORRIS PARK AVENUE. BRONX, N Y. Study of membrane
permeability by NMR relaxation (human).
-17576-04 (BBCB) BARENHOLZ, YECHEZKEL, UNIVERSITY OF VIRGINIA
BIOCHEMISTRY DEPARTMENT, CHARLOnESVILLE, VA. Role of sphingo-
myelin in biomembranes and bilayers (rats, other mammals)
■17578-04 (AFY) WESSEL, HANS U, CHILDREN'S MEMORIAL HOSPITAL
2300 CHILDREN'S PUZA, CHICAGO, ILL. Exercise performance in chil-
dren with heart disease.
■ 17580-04 (EDO HOROWITZ, MARDI J, UNIVERSITY OF CALIFORNIA 401
PARNASSUS AVENUE, SAN FRANCISCO, CALIF. The impact of stre'ss on
coronary heart disease (men).
17581-03 (CVA) BUCHANAN, JAMES W, UNIVERSITY OF PENNSYLVANIA
3800 SPRUCE STREET. PHIUDELPHIA. PA. Patent ductus arteriosus
and pulmonary hypertension (dogs).
17591-03 (CVA) KOLIN, ALEXANDER, UNIVERSITY OF CALIFORNIA
BIOPHYSICS UBORATORY, LOS ANGELES, CALIF. Development of elec-
tromagnetic rheoangiography (human, dogs).
-17592-03 (CVB) ALPERT, NORMAN R, UNIVERSITY OF VERMONT GIVEN
BUILDING. BURLINGTON, VT. Activation and contraction heat' in en-
larged hearts (rabbits).
-17596-03 (PTHA) ANDERSON, NORMAN D, JOHNS HOPKINS HOSPITAL
CMSC 6-123, 601 N BROADWAY, BALTIMORE, MD. Leukocyte-endotheli-
al interactions (rats).
-17597-05 (MET) NISHIOA, TOSHIRO, UNIVERSITY OF ILLINOIS. BURNSIDES
RESEARCH UBORATORY , URBANA. ILL. Role of plasma lipoproteins in
atherosclerosis (swine, human).
■17604-03 (AFY) WEAVER, CHARLES S, STANFORD RESEARCH INST. 333
RAVENSWOOD AVENUE. MENLO PARK. CALIF. Wearable blood pressure
and ECG recording system.
•17623-05 (SGYB) KIM, SUNG-WAN, UNIVERSITY OF UTAH. COLLEGE OF
PHARMACY. SALT UKE CITY, UTAH. Initial events in thrombus forma-
tion on surfaces (human, rats).
■17628-03 (CVB) YONCE, LLOYD R, UNIVERSITY OF NORTH CAROLINA DE-
PARTMENT OF PHYSIOLOGY. CHAPEL HILL, N C. Pulsatile pressure-flow
dynamics (dogs).
17629-03 (CVB) BOERTH, ROBERT C, VANOERBILT UNIVERSITY DIV OF
PEDIATRIC CARDIOLOGY, NASHVILLE, TENN. Developmental aspects of
cardiovascular function (human, cats, rabbits),
17631-05 (CVB) SPANN, JAMES F, JR, TEMPLE UNIVERSITY. 3400 NORTH
BROAD STREET, PHIUDELPHIA, PA. Experimental congestive heart
failure and hypertrophy (cats),
-17646-04 (SRC) SOBEL, BURTON E, WASHINGTON UNIVERSITY, 660 SOUTH
EUCLID, ST LOUIS, MO, Study of ischemic heart disease.
■17646-04 0001 (SRC) SOBEL, BURTON E. Study of ischemic heart dis-
ease-Core clinical investigation unit.
17646-04 0002 (SRC) MARKHAM, JOANNE. Study of ischemic heart
disease -Core data management.
17646-04 0003 (SRC) WILLIAMSON, JOSEPH R. Study of ischemic heart
disease-Core pathology facility (human, dogs).
17646-04 0004 (SRC) HENRY, PHILIP D. Study of ischemic heart disease-
Core experimental animal laboratories.
SS3
PROJECT NUMBER AND INVESTIGATOR ADDRESS
PSOHl- 17646-04 0005 (SRC) SOtll, lURTON E. Study of ischamic heart dis
ease 6Biochamical maiKers and medi<itot!> ol myocardial Ischemic in|u
ry
PSOHl- 17646-04 0006 (SRC) MARKHAM, JOANNE. Study oi ischemic heart
disease Mathematical models lor predicting inlirct slie using CPK
and other marKers
PSOHl-l 7646-04 0007 (SRC) ROBERTS. ROBERT. Study ol ischemic heart dis-
ease Prediction ol myocardial ischemic injury by analysis ol plasma
CPK isoenzymes
PSOHl- ) 7646-04 0009 (SRC) SOBEl, BURTON E. Study ol ischemic heart dis
ease Regional metabolic derangements indicating ischemia (rabbit,
dog. human)
PSOHl- 17646-04 0010 (SRC) lUDBROOK, PHIIIP A. Study ol ischemic heart dis
ease Compliance m ischemic myocardium Altered cardiac per
lormance (human, dogs)
PSOHl-l 7646-04 0012 (SRC) WIILIAMSON. JOSEPH R. Study ol ischemic heart
disease Role ol microcirculation in progression ol myocardial
ischemic injury (rat).
PSOHl-l 7646-04 0013 (SRC) WEIDON, ClARENCE S. Study of Ischemic heart
disease Maintenance of myocardial vascular integrity after revascu-
lari2ation (dogs)
PSOHl-l 7646-04 0014 (SRC) HENRY, PHIIIP O. Study ol ischemic heart disease-
Progression of ischemic injuiv in conscious dogs (also rabbits).
PSOHl-l 7646-04 001 S (SRC) ROBERTS, ROBERT. Study ol ischemic heart dis-
ease Protecting ischemic myocardium in patients with evolving
myocardial mlarction.
PSOHl- 17646-04 0016 (SRC) NEEDLEMAN, PHIIIP. Study of Ischemic heart dis-
ease-Humoral factors in ischemic heart rhythm, mechanical per-
formance (dog. rabbit).
PSOHl- 17646-04 0017 (SRC) SOBEl. BURTON E. Study of ischemic heart dis-
ease-Dysrhythmia associated with acute myocardial inlarction
(human, cat)
PSOHl-1 7648-04 (SRC) RESNEKOV, lEON, UNIVERSITY OF CHICAGO, 950 EAST
59TH STREET, CHICAGO, ILL. Study ol ischemic heart disease.
PSOHl-l 7648-04 0004 (SRC) HARPER. PAUL V. Study of ischemic heart disease-
-Radionuclide imaging studies (human, pig).
PSOHl-l 7648-04 0006 (SRC) BROOKS, HAROID I. Study of ischemic heart dis-
ease-Ventricular performance and myocardial perlusion In obstructive
coronaiv disease.
PSOHl- 17648-04 0011 (SRC) SKINNER. DAVID B. Study ol Ischemic heart dis-
ease-Surgical treatment lor acute myocardial ischemia (human,
dogs).
PSOHL-1 7648-04 0012 (SRC) ANAGNOSTOPOUIOS. C E. Study of ischemic
heart disease -Retrograde coronary venous perlusion-Acute myocardial
ischemia.
PSOHl- 1 7648-04 0013 (SRC) GIAGOV, SEYMOUR. Study of ischemic heart dis-
ease-Fate of bypassed and bypassing vessels (dogs).
PSOHL-1 7648-04 0014 (SRC) ARNSDORF. MORTON f. Study ol ischemic heart
disease-Antidysrhythmic drugs and mammalian cardiac PurKlnje
libers (sheep, dog).
PSOHl-1 7648-04 0016 (SRC) COHEN, HOWARD C. Study of Ischemic heart dis-
ease-lntraventricular conduction -Effect of pacing on conduction and
automaticity.
PSOHl-l 7648-04 0018 (SRC) CHIIDERS, RORY W. Study of ischemic heart dis-
ease-Myocardial damage-Infarction vectors recalled by premature
atrial stimulation.
PSOHl-l 7648-04 0020 (SRC) WISSIER. ROBERT W. Study of ischemic heart dis-
ease-Core pathology laboratory-lschemic heart disease (human,
animal).
PSOHl-l 7648-04 0021 (SRC) BROOKS. HAROLD I. Study of ischemic heart dis-
ease-Biventricular contractile responses to acute myocardial infarc-
tion (mammals).
PSOHl-l 7648-04 0023 (SRC) COHEN. LOUIS. Study of ischemic heart disease-
Chemical mediators of inflammation in acute myocardial infarction
(mammals).
PSOHl-l 7648-04 0025 (SRC) ZAK, RADOVAN. Study of ischemic heart disease-
Destruction and repair of cardiac muscle cell constituents (rat).
PSOHL- 17648-04 0026 (SRC) FISCHMAN. DONALD A. Study of ischemic heart
disease-Control of muscle cell proliferation (organ culture).
PSOHL-1 7648-04 0027 (SRC) GETZ. GODFREY. Study of ischemic heart disease-
Phospholipid metabolism following cardiac injury and repair (rat).
PSOHl- 17648-04 0028 (SRC) FOZZARD. HARRY A. Study of ischemic heart dis-
ease-Electrophysiology of sympathetic innervation in tissue culture.
PSOHl- 17648-04 0031 (SRC) PAGE, ERNEST. Study of ischemic heart disease-UI-
trastructural consequences of myocardial ischemia (rat).
PSOHL-1 7648-04 0032 (SRC) MEIER, PAUL. Study of ischemic heart disease-Data
management-Statistics and data files.
PSOHl-1 7648-04 0033 (SRC) KINIAS, PLATO. Study of ischemic heart disease-
Data management -Electrocardiographic analysis system.
P50HL-1 7648-04 0034 (SRC) PAI, A L. Study of ischemic heart disease-Data
management-Hemodynamic data.
PSOHL- 1765 1-04 (HEPA) SWAN, HAROLD J, 8700 BEBERLY BLVD. 4833 FOUN-
TAIN AVENUE, LOS ANGELES, CALIF. Ischemic heart disease special-
ized center of research.
P50HL-1 765 1-04 0002 (HEPA) GANZ. WILLIAM. Ischemic heart disease special-
ized center of research-Reduction of myocardial ishemic injury by
pharmacologic agents (human, dog).
PSOHl-1 765 1-04 0015 (HEPA) VYDEN. JOHN K. Ischemic heart disease special-
ized center of research-Peripheral circulation in acute myocardial
ischemia and Inlarction (human).
PSOHl- 1765 1-04 0016 (HEPA) CORDAY. ELIOT. Ischemic heart disease special-
ized center of research-Retroperfusion of coronary venus circulation
with therapeutic agents (dogs).
PSOHl-1 765 1-04 0022 (HEPA) MANDEl. WILLIAM J. Ischemic heart disease
specialized center of research-Electrophysiology-Mechanism and phar-
macology of arrhythmias (human, dog).
PSOHL-1 7651 -04 0023 (HEPA) GANZ. WILLIAM. Ischemic heart disease special-
ized center of research-Development of multipurpose catheter for
monitoring and electronic pacing.
PSOHl-l 765 1-04 0032 (HEPA) GRAY. RICHARD. Ischemic heart disease special-
ized center of research -Cardiovascular surgery core (human, dogs),
P50HL-1 765 1-04 0033 (HEPA) STANKUS, KATHERINE E. Ischemic heart dis-
ease specialized center ol research-Core facilities-Computer sciences.
PSOHl- 176S 1-04 0034 (HEPA) STANKUS, KATHERINE E. Ischemic heart dis-
ease specialized center ol research-Core facilities-Data management.
PSOHl-1 76S 1-04 0035 (HIPA) VAS, RAN. lichfinic htirl diMlu ipeciali/(d
center of lesearch Core lacilities Biomedical engineering. biophytic\
PS0HI-I76SI-04 0036 (HEPA) SHIll, WILLIAM. Ischemic heart diseau special
i/ed center ol research Core lacililies Cardiovascular pathology
(human, dog)
PSOHl- 176S 1-04 0037 (HEPA) GANZ, WILLIAM. Ischemic heart diuate special
ized center ol research Measurement ol coronary venous outflow by
Ihernodilution (human)
PSOHl-1 7651-04 0038 (HEPA) GANZ, WILLIAM. Ischemic head diMise special
ized center ol research Cardiothermography (human, dog)
PSOHl- 1 765 1-04 0039 (HEPA) SHELL, WILLIAM E. Ischemic heart disease spe
cialized center ol research Measurement and prediction ol inlarcl size
(human, dog)
PS0HL-I765I-04 0041 (HEPA) SHEU, WILLIAM E. Ischemic heart disease spe
cialized center ol research Biochemical indices ol ischemic injury
(guinea pig)
PS0HL-176S1-04 0043 (HEPA) MEERBAUM, SAMUEL. Ischemic heart disease
specialized center ol research Gradual reperfusion lollowing acute
coronary occlusion (dog)
P50HL-17651-04 0044 (HEPA) GRAY. RICHARD. Ischemic heart disease special-
ized center ol research -Limb blood flow after myocardial revascu-
larization (human).
PS0HL-I76S1-04 0045 (HEPA) VYDEN. JOHN K. Ischemic heart disease special-
ized center ol research -Peripheral vascular studies- Pharmacology
(dogs, human)
PSOHl- 1765 1-04 0046 (HEPA) SINGH, BRAMAH N. Ischemic heart disease spe
cialized center of research -Clinical core-Physiological
changes/biochemical effects ol myocardial ischemia
P50HI-1 765 1-04 0047 (HEPA) GANZ, WILLIAM. Ischemic heart disease special-
ized center of research -Clinical core Automated arrhythmia monitor
ing system
PSOHl-1 765 1-04 0048 (HEPA) SINGH, BRAMAH N. Ischemic heart disease spe-
cialized center of research-Noninvasive detection of ischemic heart
disease.
PSOHl-1 7655-04 (SRC) WEISFEIDT, MYRON I, JOHNS HOPKINS UNIVERSITY, 601
NORTH BROADWAY, BALTIMORE, MO Study of ischemic heart disease.
PSOHl-1 7655-04 0001 (SRC) BUIKIEY. BERNADINE H. Study of ischemic heart
disease -Intravenous nitroglycerin-Ventricular function and infarct size
(human, dog).
PSOHl-l 76SS-04 0003 (SRC) WEISFEIDT, MYRON I. Study of ischemic heart
disease -Cardiopulmonary resuscitation (human, dog).
PSOHL-1 7655-04 0004 (SRC) HUMPHRIES. J ONEAL. Study of ischemic heart
disease-Coronary arteriography in survivors of acute myocardial in-
farction (human).
PSOHl-1 7655-04 0006 (SRC) GRIFFITH. LAWRENCE S C. Study of ischemic
heart disease-Evaluation ol coronary artery bypass graft surgery
(human).
PSOHl-1 7655-04 0009 (SRC) BECKER, LEWIS. Study of ischemic heart disease -
Random trial of medical and surgical therapy in unstable angina
(human).
PSOHl-1 7655-04 0010 (SRC) HUTCHINS. GROVER M. Study of ischemic heart
disease -Core facility-Cardiovascular pathology (human, animal).
PSOHL-1 7655-04 0011 (SRC) BECKER. LEWIS C. Study of ischemic heart disease-
-Core facility-Cardiovascular nuclear medicine (human, dog).
PSOHL-1 7655-04 0012 (SRC) BUROW. ROBERT D. Study of ischemic heart dis-
ease-DATA management.
PSOHl-1 7655-04 0014 (SRC) FLAHERTY. JOHN T. Study of ischemic heart dis-
ease-Blood flow and gas tension in myocardial ischemia and infarc-
tion (dog, monkey).
PSOHl-1 7665-04 (SRC) HABER. EDGAR, MASSACHUSETTS GENERAL HOSPITAL,
FRUIT STREET, BOSTON, MASS. Study of ischemic heart disease.
PSOHl-1 7665-04 0001 (SRC) lEINBACH, ROBERT C. Study of ischemic heart
disease -Reduction of acute anterior myocardial infarction-Mechanical
circulatory assist.
PSOHL-1 7665-04 0002 (SRC) GOLD. HERMAN K. Study of ischemic heart dis-
ease-Reducing acute anterior myocardial infarction-Beta adrenergic
blockade (human).
PSOHL-1 7665-04 0003 (SRC) lEINBACH, ROBERT C. Study of ischemic heart
disease-Quantitation of injury-Acute myocardial Infarction com-
plicated by shock (human).
PS0HL-1766S-04 0005 (SRC) GOLD. HERMAN K. Study of ischemic heart dis-
ease-Evaluation of zone of jeopardized myocardium in patients with
angina pectoris.
PSOHL-1 7665-04 0008 (SRC) MAROKO. PETER R. Study of ischemic heart dis-
ease-Core laboratory -CPK isoenzyme measurement and myocardial
necrosis evaluation.
P50HL-1 7665-04 0011 (SRC) GOLD. HERMAN K. Study of ischemic heart dis-
ease-Development of new methods for the determination of infarct
size (dog, human).
P50HL-1 7665-04 0012 (SRC) VATNER. STEPHEN F. Study of ischemic heart dis-
ease-Myocardial ischemia -Cardiovascular performance in the con-
scious baboon and dog.
P50HL-1 7665-04 0013 (SRC) HUTTER, ADOLPH M. Study of ischemic heart dis-
ease-National cooperative study in unstable angina pectoris (human).
PSOHl-l 7665-04 0018 (SRC) HUTTER, ADOLPH M. Study of ischemic heart dis-
ease-Computer correlation of data -Patients with Ischemic heart dis-
ease.
PSOHL-1 7665-04 0020 (SRC) BUCKLEY, MORTIMER J. Study of ischemic heart
disease-lschemic injury to myocardium during measured states of
ischemia (human).
P50HL-1 7665-04 0021 (SRC) LEVINE. FREDERICK D. Study of ischemic heart
disease-Identification, prevention-Myocardial ischemia in cardiopul-
monary bypass (dog).
PSOHl-1 7665-04 0022 (SRC) LEVINE. FREDERICK H. Study of Ischemic heart
disease-Effect of coronary revascularization on left ventricular func-
tion (human).
P50HL-I 7665-04 0026 (SRC) LOWENSTEIN, EDWARD. Study of ischemic heart
disease -Anesthesia-Myocardial ischemia and hemodynamics in coro-
nary disease (human).
P50HL-1 7665-04 0027 (SRC) STRAUSS. H WILLIAM. Study of ischemic heart
disease -Positron imaging of regional myocardial perfusion (human,
dog).
P50HL-1 7665-04 0028 (SRC) TRELSTAD. ROBERT I. Study of ischemic heart dis-
ease-Pathologic and biochemical studies of ischemic myocardium
(human, dog).
#m
PROJECT NUMBER AND INVESTIGATOR ADDRESS
PSOHl-l 7665-04 0029 (SRC) TAEGTMEVER, HEINRICH. Study of ischemic heart
disease-Myocardial protein synthesis and degradation in low oxygen
states (rabbit, dog).
P50HL-1 7665-04 0030 (SRC) KAPLAN, EDWARD M. Study of ischemic heart
disease-Data management.
PSOHl-1 7665-04 0032 (SRC) KHAW, BAN AN. Study of ischemic heart disease--
Myocardial infarct sizing-lmmunoassay for cardiac myosin light
chains (dogs).
P50HL-1 7667-04 (SRC) RACKLEY, CHARLES E, UNIVERSITY OF ALABAMA UNIVER-
SITY STATION, BIRMINGHAM, ALA. Study of ischemic heart disease
P50HL- 1 7667-04 0001 (SRC) OBERMAN, ALBERT. Study of ischemic heart dis-
ease-Natural history of ischemic heart disease (human)
PSOHL-1 7667-04 0012 (SRC) REDDY, WILLIAM J. Study of ischemic heart dis-
ease-Biochemistry of normal and ischemic heart-Glycolysis (rats)
PSOHL- 17667-04 0018 (SRC) MANTLE, JOHN A. Study of ischemic heart dis-
ease-Arrhythmias in ischemic heart disease (human)
PSOHL-1 7667-04 0019 (SRC) KOUCHOUKOS, NICHOLAS T. Study of ischemic
heart disease-Assessment of long-term results of coronary artery
bypass grafting (human).
PSOHL- 17667-04 0022 (SRC) BLACKSTONE, EUGENE H. Study of ischemic
heart disease-Preventing myocardial injury in surgery using cardiopul-
monary bypass (human, rat).
PSOHL- 17667-04 0029 (SRC) WALDO, ALBERT L. Study of ischemic heart dis-
ease-Computer diagnosis of cardiac arrhythmias after open heart sur-
gery (human)
PSOHL-l 7667-04 0030 (SRC) WIXSON, STEVEN E. Study of ischemic heart dis
ease-Computerized clinical data acquisition and processing
PSOHL-l 7667-04 0031 (SRC) JAMES, THOMAS N. Study of ischemic heart dis
ease-Pathophysiology in ischemic heart disease (dog, cat, rabbit,
monkey).
PSOHl-1 7667-04 0038 (SRC) RACKLEY, CHARLES E. Study of ischemic heart
disease-Clinical core unit.
PSOHL-l 7667-04 0039 (SRC) HOOD, WILLIAM P. Study of ischemic heart dis
ease -Core human investigative laboratories
PSOHL-l 7667-04 0040 (SRC) MCDANIEL, HUEY G. Study of ischemic heart dis
ease-Core biochemistry-Cardiac metabolism (human)
P50HL-17667-04 0041 (SRC) MACY, JOSIAH, JR. Study of ischemic heart dis-
ease-Biophysical sciences core-Data collection and retrieval
PSOHL-1 7667-04 0042 (SRC) WIXSON, STEVEN E. Study of ischemic heart dis
ease-Core-Central instrumentation and software
PSOHL- 17667-04 0043 (SRC) MCDANIEL, HUEY G. Study of ischemic heart dis-
ease-Quantitation of myocardial infarct size by serial enzyme mea-
surements (human).
PSOHL-1 7667-04 0044 (SRC) SMITH L. RICHARD. Study of ischemic heart dis-
ease-Core-Data management and analysis.
PSOHL-l 7667-04 0045 (SRC) BISHOP, SANFORD P. Study of ischemic heart dis-
ease-Pathology of myocardial ischemic necrosis (human)
PSOHL-1 7669-04 (SRC) WILLERSON, JAMES T, UNIVERSITY OF TEXAS 5323
HARRY HINES BOULEVARD, DALLAS, TEX. Ischemic heart disease
center (SCOR).
PSOHL-l 7669-04 0001 (SRC) STONE, MARVIN J. Ischemic heart disease center
(SCOR)-Radioimmunoassays for CPK isoenzyme and myoglobin
(human, dog).
PSOHL-1 7669-04 0002 (SRC) SMITHERMAN, THOMAS C. Ischemic heart dis-
ease center (SCOR) -Myocardial infarction sizing by radioimmunoassay
of cardiac myosin (dogs).
PSOHL-1 7669-04 0006 (SRC) WILLERSON, JAMES T. Ischemic heart disease
center (SCOR)-Studies of hypoxic, acidotic and ischemic cardiac
muscle (dogs).
P50HL-1 7669-04 0007 (SRC) TEMPLETON, GORDON H. Ischemic heart disease
center (SCOR)-Relationship between myocardial depression and com-
pliance (dogs, cats).
PSOHL-l 7669-04 0008 (SRC) LIPSCOMB, KIRK. Ischemic heart disease center
(SCOR)-Segmental ventricular dysfunction during stress-induced
ischemia (dog, human).
PSOHL-l 7669-04 0009 (SRC) PARKEY, ROBERT W. Ischemic heart disease
center (SCOR)-lnfarct volume-99Tc stannous pyrophosphate myocardi-
al scintigrams (dogs, human).
PSOHL-l 7669-04 0011 (SRC) WILDENTHAL, C KERN. Ischemic heart disease
center (SCOR)-Lysosomal function and lysosomal enzymes in normal
and ischemic heart (rabbit).
PSOHL-l 7669-04 0012 (SRC) EBERHART, ROBERT C. Ischemic heart disease
center (SCOR) -Circulatory assistance (human, dog)
PSOHL-l 7669-04 0013 (SRC) BIOMQVIST, C GUNNAR. Ischemic heart disease
center (SCOR) -Exercise in patients with ischemic heart disease
PSOHL-l 7669-04 0022 (SRC) BUJA, L MAXIMILIAN. Ischemic heart disease
center (SCOR)-Pathological studies of human and experimental
ischemic heart disease.
PSOHL- 17669-04 0023 (SRC) WILLERSON, JAMES T. Ischemic heart disease
center (SCOR)-Patients with acute myocardial infarction and myocar-
dial ischemia (human).
PSOHL- 1 7670-04 (SRC) ROSATI, ROBERT A, DUKE HOSPITAL, BOX 3337, DURHAM,
N C. Study of ischemic heart disease.
PSOHL-l 7670-04 0001 (SRC) ROSATI, ROBERT A. Study of ischemic heart dis
ease -Data management.
PSOHL-l 7670-04 0005 (SRC) GREENFIELD, JOSEPH C. Study of ischemic heart
disease -Quantitative assessment of the vectorcardiogram (human)
PSOHL- 1 7670-04 0006 (SRC) OLDHAM, H NEWLAND. Study of ischemic heart
disease-Assessment of coronary artery hemodynamics and myocardial
blood flow (human).
PSOHL-l 7670-04 0008 (SRC) GALLAGHER, JOHN J. Study of ischemic heart
disease-Surgical treatment of cardiac rhythm disorders (human,
dogs).
PSOHL- 17670-04 0009 (SRC) WECHSLER, ANDREW S. Study of ischemic heart
disease-Surgical treatment of localized left ventricular dyssynergy
(human, dogs).
PSOHL- 17670-04 0011 (SRC) STRAUSS, HAROLD C. Study of ischemic heart dis
ease-Pharmacology of ischemic myocardium (dogs)
P50HL- 17670-04 0012 (SRC) WAGNER, GALEN S. Study of ischemic heart dis
ease-Epidemiology of sudden death (human).
PSOHL-l 7670-04 0014 (SRC) VONRAMM, OLAF T. Study of ischemic heart dis
ease-Real lime ultrasound imaging in ischemic heart disease
(human, dog).
PSOHL-l 7670-04 0015 (SRC) JONES, ROBERT H. Study of ischemic heart dis
ease-Radionuclide studies of myocardial ischemia (human).
554
PSOHL-l 7670-04 0016 (SRC) HACKEL, DONALD B. Study of ischemic heart dis
ease -Core pathology laboratory (human, dogs, monkeys).
PSOHL-1 7670-04 0017 (SRC) ROE, CHARLES R. Study of ischemic heart disease-
Core enzymology laboratory (human).
PSOHL-l 7670-04 0018 (SRC) GREENFIELD, JOSEPH C. Study of ischemic heart
disease-Core electrocardiogram laboratory (human).
PSOHL-l 7670-04 0020 (SRC) COBB, FREDERICK R. Study of ischemic heart dis-
ease-Radionuclide evaluation of coronary artery disease (human,
dog).
PSOHL-1 7670-04 0021 (SRC) ROE, CHARLES R. Study of ischemic heart disease-
Enzymatic evaluation of acute myocardial infarction (dogs).
PSOHL-1 7670-04 0022 (SRC) SNOW, T RUSSELL. Study of ischemic heart dis-
ease-Myocardial metabolism in hypoxia and recover (rabbit, toad
dog).
PSOHL-l 7670-04 0023 (SRC) JENNINGS, ROBERT B. Study of ischemic heart
disease-Energy metabolism in acute myocardial ischemic injui>
(dogs).
PSOHL-l 7682-04 (SRC) ROSS, JOHN, JR, UNIV OF CALIFORNIA, SAN DIEGO DEPT
OF MEDICINE, M-013, LA JOLLA, CALIF. Study of ischemic heart dis-
ease.
PSOHL-l 7682-04 0001 (SRC) KARLINER, JOEL S. Study of ischemic heart dis-
ease-Studies in acute and chronic ischemic heart disease (human)
PSOHL-l 7682-04 0003 (SRC) PETERSON, KIRK L. Study of ischemic heart dis-
ease-Effects of myocardial revascularization in man
PSOHL-l 7682-04 0005 (SRC) PETERSON, KIRK L. Study of ischemic heart dis
ease-Regional myocardial perfusion deficits and segmental contrac-
tion disorders in man.
P50HL-1 7682-04 0007 (SRC) WEST, JOHN B. Study of ischemic heart disease-
Mechanisms of hypoxemia in myocardial infarction (human)
PSOHL-l 7682-04 0008 (SRC) KARLINER, JOEL S. Study of ischemic heart dis
ease-Clinical core unit.
PSOHL-l 7682-04 0009 (SRC) COVELL, JAMES W. Study of ischemic heart dis-
ease-Computer core unit.
PSOHL-1 7682-04 0010 (SRC) DELUCA, MARLENE A. Study of ischemic heart
disease -Core clinical enzyme laboratory (human, mice, dogs, rats)
P50HL-1 7682-04 0011 (SRC) ASHBURN, WILLIAM L. Study of ischemic heart
disease-Nuclear medicine core unit (human, dogs, rabbits, mice)
P50HL-1 7682-04 0012 (SRC) BLOOR, COLIN M. Study of ischemic heart disease
-Pathology core laboratory (human).
PSOHL-l 7682-04 0013 (SRC) COVELL, JAMES w. Study of ischemic heart dis-
ease-Chronic ischemic heart disease-Myocardial function and
metabolism (dogs, swine).
PSOHL-1 7682-04 0014 (SRC) FRANKLIN, DEAN L. Study of ischemic heart dis-
ease-Myocardial ischemia-Instrumentation and technique (dogs,
baboons).
PSOHL-1 7682-04 0015 (SRC) ROSS, JOHN, JR. Study of ischemic heart disease-
Acute myocardial ischemia and infarction and their reversibility (dogs,
baboons).
PSOHL-l 7682-04 0016 (SRC) BLOOR, COLIN M. Study of ischemic heart disease-
Endurance exercise-Prevention and rehabilitation in ischemic heart
disease (pig).
PSOHL-l 7682-04 0018 (SRC) DELUCA, MARLENE A. Study of ischemic heart
disease-Biochemistry of ischemia -Heart cell and organ culture (mice,
rats, cattle).
PSOHL-l 7682-04 0020 (SRC) MAYER, STEVEN E. Study of ischemic heart dis-
ease-Nucleotide and nucleoside metabolism in ischemic myocardium
PSOHl-l 7682-04 0021 (SRC) PRINTZ, MORTON P. Study of ischemic heart dis-
ease-Prostaglandin biosynthesis in blood vessels from ischemic
myocardium (rat. sheep).
PSOHL-l 7682-04 0023 (SRC) DELUCA, MARLENE A. Study of ischemic heart
disease-Core cell and organ culture laboratory (mice)
PSOHL-1 7682-04 0024 (SRC) STULL, JAMES T. Study of ischemic heart disease-
Phosphoiylation of cardiac contractile proteins during ischemia (rat,
guinea pig).
R01HL-17689-06 (CVA) ELDRIDGE, FREDERIC L, UNIVERSITY OF NORTH
CAROLINA, DEPT OF PHYSIOLOGY, CHAPEL HILL, N C. Neurophysiologic
studies of respiratory control (cats).
R01HL-17702-04 (PHY) MORAD, MARTIN, UNIVERSITY OF PENNSYLVANIA DE-
PARTMENT OF PHYSIOLOGY, PHILADELPHIA, PA. Electro-optical dyes as
probes of heart excitability.
ROIHL-1 7705-04 (CVB) MARGOLIUS, HARRY S, MED UNIV OF SOUTH CAROLINA
80 BARRE STREET, CHARLESTON, S C. Kallikrein-kinin system in hyper-
tension (human, rats, dogs).
ROlHL-1 7706-04 (EXP) HENRY, JAMES P, UNIV OF SOUTHERN CALIFORNIA 815 W
37TH STREET, LOS ANGELES, CALIF. Psychosocial hypertension,
catecholamines and drugs (mice).
ROlHL-17710-04 (GEN) BAGLIONI, CORRADO, S U N Y AT ALBANY 1400
WASHINGTON AVENUE, ALBANY, N Y. Selective replication of
hemoglobin genes (mice, ducks, human).
ROlHL-17711-05 (CVB) BERGOFSKY, EDWARD H, DEPARTMENT OF MEDICINE
STATE UNIVERSITY OF NEW YORK, STONY BROOK, N Y. Mechanism of
hypoxic regulation of lung circulation (rats, cats, guinea pigs)
ROlHL-l 77 15-04 (PHY) SHANNON, ROGER, UNIVERSITY OF SOUTH FLORIDA DE-
PARTMENT OF PHYSIOLOGY, TAMPA, FLA. Respiratory muscle afferents
in respiratory control (cats).
ROlHL-17719-03 (CVA) TIERNEY, DONALD F, UNIVERSITY OF CALIFORNIA DE-
PARTMENT OF MEDICINE, LOS ANGELES, CALIF. Lung injury, substrate
utilization, oxygen toxicity (rats, rabbits, dogs)
ROlHL-17721-04 (CVB) FISCHER, GRACE M, BOCKUS RESEARCH INSTITUTE 19TH
AND LOMBARD STREETS, PHIUDELPHIA, PA. Effect of sex hormones on
vascular connective tissue (rats).
ROlHL-1 7724-03 (CVB) LEW, GLORIA M, MICHIGAN STATE UNIVERSITY DEPART-
MENT OF ANATOMY. EAST LANSING, MICH. Oral contraceptives and
hypertension (rats).
ROlHL-1 7726-03 (HEM) KINGDON, HENRY S, UNIVERSITY OF NORTH CAROLINA
DIVISION OF HEMATOLOGY. CHAPEL HILL. N C. Bacterial heparinase in
diagnostic coagulation studies.
ROlHL-1 7729-04 (HEM) DETWILER, THOMAS C, S U N Y - OOWNSTATE MED CTR
450 CLARKSON AVENUE, BROOKLYN. N Y. Stimulus-response coupling
in platelets (human).
P01HL-17731-04 (HEPA) WEST, JOHN B, UNIVERSITY OF CALIFORNIA DEPART-
MENT OF MEDICINE, LA JOLLA, CALIF. Physiological basis of pulmonary
disease.
POlHL-17731-04 0001 (HEPA) WEST, JOHN B. Physiological basis of pulmonary
disease-Mechanisms of blood flow and ventilation (dogs).
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S5S
17731-04 OOOa (HIPA) FUNO. YUAN-CHINO •. Physiolo|lcil basis ol
pulmonary disease Biomtchanics ol the lun| (lio|s, cats)
17731-04 0003 (HiPA) KOOYMAN. OERAID I. PhyslolOBIcal basis ol
pulmonary disease Compaialive physiology (vertebiales)
17731-04 0006 (HEPA) WAONER, PETER 0. Physiolo|lcal basis ol pul
monary disease Ventilation peilusion latios (human, dogs)
17731-04 0007 (HIPA) EVANS, JOHN W. Physiological basis ot pulmo
nary disease Theoietical g^s exchange
17731-04 0010 (HEPA) Hill, ESTHER P. Physiological basis o( pulmonaiy
disease Gas exchange kinetics (dogs)
• 17731-04 0011 (HEPA) WEST, JOHN B. Physiological basis ol pulmonaiy
disease Moiphometiic studies ol the lung Core
.17731-04 0012 (HEPA) EVANS, JOHN W. Physiological basis ol pulmo
nary disease Statistics and computing Core
17732-03 (AfY) STOIWIJK, JAN A, JOHN B PIERCE fDN LABORATORY.
290 CONGRESS AVENUE. NEW HAVEN. CONN Peripheral wenomotor
control in thermal stress (human)
17736-04 (CVB) SHUG, AUSTIN I, VETERANS ADMINISTRATION HOSP, 2500
OVERLOOK TERRACE. MADISON. WIS Metabolic change during cardiac
ischemia (rats, dogs)
17739-04 (RAD) HOIMAN, B LEONARD, HARVARD MEDICAL SCHOOL. 50
BINNEY STREET. BOSTON. MASS Acute myocardial inlarct scintigraphy
(human, dogs, rats)
.17747-04 (PTHA) KARNOVSKY, MORRIS J, HARVARD MEDICAL SCHOOL.
25 SHAnuCK STREET. BOSTON. MASS. Endothelial injury and
regeneration (rats).
-17749-03 (CVB) NEW. MARIA I, CORNELL UNIVERSITY. 1300 YORK
AVENUE. NEW YORK. N Y Adrenocortical lactors in human hyperten-
sion (human).
-17751-03 (BM) PETERSDORF, ROBERT G, UNIVERSITY OF WASHINGTON.
1959 PACIFIC AVENUE, N E, SEAHLE. WASH. Experimental endocar-
ditis (rabbits)
17752-03 (HEM) PECHET, IIBERTO, UNIVERSITY OF MASSACHUSETTS. 55
LAKE AVENUE NORTH. WORCESTER. MASS. Puritied human clotting
lactor IX-lmmunologic studies (human).
17754-03 (CVB) OKAMOTO, KOZO, KINKI UNIVERSITY. SAYAMA-CHO.
MINAMl-KAWACHI-GUN. OSAKA-FU. JAPAN. Pathogenesis and prevention
ol hypertension sequelae (rats)
.17759-03 (SGYB) BITTAR, NEVIllE, CARDIOVASCULAR RESEARCH UB. 420
NORTH CHARTER ST. ROOM 523. MADISON. WIS. Studies of myocardial
reactive hyperemia (dogs, human).
■ 17768-04 (CVA) ROBINSON, NORMAN E, MICHIGAN STATE UNIVERSITY.
DEPARTMENT OF PHYSIOLOGY. EAST LANSING, MICH. Development of
collateral ventilation (dogs. fish, horses).
.17769-03 (RAD) JACOBS, JOHN E, NORTHWESTERN UNIVERSITY. 2145
SHERIDAN ROAD. EVANSTON, ILL New methods ol studying blood
coagulation kinetics.
17776-04 (CVA) WOOD, ROBERT E, RAINBOW BABIES & CHILDRENS HOS,
2103 ADELBERT ROAD, CLEVELAND, OHIO. Pulmonary mucus transport
in obstructive lung diseases (human).
17781-03 (CVB) PINTER, GABRIEL G, UNIVERSITY OF MARYLAND. 660
WEST REDWOOD STREET, BALTIMORE, MO. Hypertension, kidney dis-
ease and renal lymph (dogs, rats).
.17783-04 (PC) ElBEIN, ALAN D, UNIVERSITY OF TEXAS. 7703 FLOYD CURL
DRIVE. SAN ANTONIO. TEX. Complex carbohydrates-Structure, lunction.
synthesis (swine).
-17794-03 (MCHB) BALDWIN, JACK E, MASSACHUSETTS INST OF TECH.
DEPARTMENT OF CHEMISTRY. CAMBRIDGE, MASS. Chelating agents as
blood substitutes.
-17796-04 (PHRA) CALDWELL, ROBERT W, UNIVERSITY OF TENNESSEE.
800 MADISON AVENUE. MEMPHIS. TENN. Importance of aminosugars
in digitalis activity (cats, rabbits).
-17799-02 (CVB) BROWN, OLIVER M, 750 EAST ADAMS STREET.
SYRACUSE. N Y. The presence and significance of heart acetylcholine
(cats).
-17800-04 (CVA) KALIA, MADHU, HAHNEMANN MED COLL & HOSP. 230
NORTH BROAD STREET. PHIUDELPHIA, PA. Pulmonary reflexes-Central
pathways (cats. dogs, rabbits).
17808-03 (CVA) WOODSON, ROBERT D, UNIVERSITY OF WISCONSIN.
1300 UNIVERSITY AVENUE. MADISON. WIS. Effect of altered oxygen af-
finity on oxygen transport (human, rats).
17809-04 (CVA) COHEN, MICHAEL V, MONTEFIORE HOSP & MED CTR.
Ill E 210TH STREET. BRONX. N Y. Effects of exercise on the coronary
vasculature (rat. dog).
.17812-04 (HEP) TAYLOR, FLETCHER B, JR, UNIVERSITY OF OKLAHOMA.
POST OFFICE BOX 26901. OKUHOMA CITY, OKLA. Thrombosis and
plasma proteins.
.17812-04 0001 (HEP) TAYLOR, FLETCHER B, JR. Thrombosis and plasma
proteins -Thrombosis and plasma proteins (cattle, guinea pigs).
.17812-04 0002 (HEP) RADCIIFFE, ROBERT. Thrombosis and plasma
proteins-Activators of fibrinolysis-Synthesis and degradation (human,
cattle).
■ 17812-04 0004 (HEP) TAYLOR, FLETCHER B, JR. Thrombosis and plasma
proteins-Serum-platelet interaction (human).
-17812-04 0005 (HEP) GILLIAM, JAMES M. Thrombosis and plasma
proteins~ln vitro systems of normal platelets, white cells, sera
(human).
-17812-04 0007 (HEP) HINSHAW, LERNER B. Thrombosis and plasma
proteins-Blood components-Response to endotoxin (dogs, baboons).
17813-04 (HEP) HARVEY, REJANE M, COLUMBIA UNIVERSITY. 630 WEST
168TH STREET. NEW YORK. N Y. Lung disease and the oxygenation of
blood and tissue.
17813-04 0001 (HEP) ENSON, YALE. Lung disease and the oxygenation of
blood and tissue-Diffuse interstitial lung discasc-Pathophysiology
(human, dogs).
■ 17813-04 0002 (HEP) BLANC, WILLIAM A. Lung disease and the ox
ygenation of blood and tissue-Diffuse interstitial lung discase-Ultras-
tructural abnormalities (human).
-17813-04 0006 (HEP) BRAUN, NORMA. Lung disease and the oxygena-
tion ol blood and tissue -Assessment of respiratory muscle contractile
force (human, dogs).
17813-04 0007 (HEP) CALDWELL, PETER R B. Lung disease and the ox
ygenation of blood and tissue-Studies on the function of myoglobin
(dogs).
P0IHI.I7S13
R01HL17818
R0IHL-17e2l
ROlHL-17826
R01HL-17828
ROlHL-17844
R01HL-17847
R01HL-1 7853-1
R01HL-17859
ROlHL-17865-
P01HL-17871-
POlHL-17871
POlHL-17871
P01HL-17871
R01HL-17873-<
ROlHL-17878
R01HL-17879-
ROlHL-17881
R01HL-17882
ROIHL-17895
ROlHL-1 7896-1
ROlHL-17897-
R01HL-17898
R01HL-17902
ROlHl-17903
ROlHL-17907
ROlHl-17909.
ROIHl-17921
ROlHL-17930
ROlHL-17931
ROlHL-17932
ROlHL-17944
R01HL-17947
ROlHL-17954
R01HL-179S8
PROJECT NUMBER AND INVESTIGATOR ADDRESS
04 0008 (HEP) CAlDWEll, PITER R B Lung diteiM and the o.
ygenation of blood and tissue Pulmonary regulation ol systemic blood
pressure (human, rabbits, rals)
■05 (MET) SALEN, OiRALD, VETERANS ADMINISTRAIION HOSP. IRE
MONT AVENUE. EASI ORANGE. N ) Metabolism ol choleiUrol and
cholcstiMol in man (also rats, monkeys)
■03 (SGYB) WALKER. WILLIAM F. RICE UNIVERSITY. POST OFFICE
BOX 1892. HOUSTON. TEX Cavitation phenomena near prosthetic
devices
■04 (BBCB) CHANCE. BRITTON, UNIVERSITY OF PENNSYLVANIA.
SCHOOL OF MEDICINE. PHIUDELPHIA. PA Oxygen delivery to tissue
■04'(BMT) WILKINS. RALPH G. NEW MEXICO STATE UNIVERSITY. BOX
3C. LAS CRUCES. N MEX Kinetic studies ol hemeiythrin reactions
(marine worms)
-04 (SGYA) GEYER, ROBERT P, HARVARD SCHOOL OF PUB HLTH.
665 HUNTINGTON AVENUE. BOSTON. MASS Artilicial blood substitutes.
02 binding iron chelates (human, mammals)
■04 (PHY) ZATZMAN, MARVIN L, UNIVERSITY OF MISSOURI. DE-
PARTMENT OF PHYSIOLOGY. COLUMBIA. MO Cardiovascular and renal
lunctions ol marmots
.03 (CVA) ZEUS, ROBERT F. MILTON S HERSHEY MEDICAL CTR. OIVI
SION OF CARDIOLOGY. HERSHEY. PA Peripheral circulation in heart
lailure (animals). ,, „,,
04 (SGYB) PESKIN. CHARLES S, NEW YORK UNIVERSITY. 251
MERCER STREET, NEW YORK. N Y. Computational methods in cardiac
fluid dynamics __„, „,
.04 (CVB) BOUCEK. ROBERT J. JR, UNIVERSITY OF MIAMI. POST OF-
FICE BOX 520875. MIAMI. FLA. Studies on aging -Effects ol sex hor-
mones (rats, dogs)
■04 (HEP) TOBIAN, LOUIS, UNIVERSITY OF MINNESOTA HOSPS. OE
PARTMENT OF MEDICINE. MINNEAPOLIS. MINN. Kidney, sodium, cardiac
output, arterioles and hypertension.
04 0009 (HEP) ZIMMERMAN, BEN G. Kidney, sodium, cardiac
output, arterioles and hypertension- Kidney, sodium, cardiac output,
arterioles and hypertension
.04 0010 (HEP) DUNHAM, EARL W. Kidney, sodium, cardiac out-
put, arterioles and hypertension-Renal prostaglandins metabolism in
hypertension (rats. dogs).
■04 0013 (HEP) AZAR, SILVIA. Kidney, sodium, cardiac output, ar-
terioles and hypertension -Pertusion pressure and renal sodium excre-
tion (rats).
.04 (CVA) MC FADDEN, EDWARD R, JR, PETER BENT BRIGHAM
HOSPITAL 721 HUNTINGTON AVENUE, BOSTON. MASS. Pathophysiology
ol exercise-induced asthma (human).
.04 (BBCB) BRANDTS, JOHN F, UNIVERSITY OF MASSACHUSETTS,
DEPARTMENT OF CHEMISTRY. AMHERST. MASS. Structural studies ol
the human erythrocyte membrane.
■04 (MBY) KYTE, JACK E, UNIV OF CALIFORNIA, SAN DIEGO, DEPT OF
CHEMISTRY, B-017, LA JOLLA, CALIF. Molecular structure of the
ouabain sensitive ATPase (dogs).
-15 (HEM) AMINOFF, DAVID, UNIVERSITY OF MICHIGAN. 102 OB-
SERVATORY STREET. ANN ARBOR. MICH Biosynthesis and degradation
ol blood group substances (human, animals).
-04 (PC) SHAPIRO, DAVID J. UNIVERSITY OF ILLINOIS. DEPARTMENT
OF BIOCHEMISTRY. URBANA. ILL Regulation ol HMG-COA reductase
and sterol synthesis (human, mammals).
■04 (CVB) ROVETTO. MICHAEL J. THOMAS JEFFERSON UNIVERSITY.
PHYSIOLOGY DEPARTMENT. PHILADELPHIA, PA. Myocardial function and
metabolism following ischemia (rats).
.03 (MCHA) STAMMER, CHARLES H, UNIVERSITY OF GEORGIA.
CHEMISTRY DEPARTMENT. ATHENS. GA. Dehydropeptide renin sub-
strates.
.03 (MCHA) COOK, JAMES M. UNIVERSITY OF WISCONSIN. DEPART-
MENT OF CHEMISTRY. MILWAUKEE, WIS. Synthesis of alpha and beta
adrenergic antagonists.
.03 (PC) KWITEROVICH. PETER O, JOHNS HOPKINS HOSPITAL 600
NORTH WOLFE STREET, BALTIMORE. MD. Cell membranes and plasma
lipoproteins (human, swine).
-04 (CVB) GILMORE, JOSEPH P, UNIVERSITY OF NEBRASKA, 42ND
AND DEWEY. OMAHA. NEBR. Mammalian renal microcirculation
(hamsters).
-03 (CVA) SONNENSCHEIN, RALPH R, UNIVERSITY OF CALIFORNIA.
405 HILGARD AVENUE. LOS ANGELES. CALIF. Regional circulatory
responses to hypoxia (rats. cats, rabbits).
-04 (CVB) SKINNER, JAMES E, BAYLOR COLLEGE OF MEDICINE.
1200 MOURSUND AVENUE. HOUSTON. TEX. Brain regulation of cardiac
arrhythmia (pigs. cats. rats).
.04 (CVB) BOUCEK, ROBERT J. JR, UNIVERSITY OF MIAMI. P 0 BOX
520875, BISCAYNE ANNEX, MIAMI. FLA. Drug treatment of vascular
scleroprotein defects (human, turkeys).
■04 (MCHA) PORTER, NED A, DUKE UNIVERSITY. DEPARTMENT OF
CHEMISTRY. DURHAM. N C. Pcroxy radicals to prostaglandins in ves-
sels and lung
-03 (HEM) HARBURY, CHRISTINA B, STANFORD UNIVERSITY. 300
PASTEUR DRIVE, STANFORD. CALIF. Platelet membrane function-As-
sessment and application (animals).
-04 (CVB) PIONSEY, ROBERT, CASE WESTERN RESERVE UNIV,
10900 EUCLID AVENUE. CLEVELAND. OHIO. Normalized body surface
potential maps (children).
-04 (CVA) BOCKMAN, EMMA L, LOUISIANA STATE UNIVERSITY.
1542 TULANE AVENUE. NEW ORLEANS. LA. Blood flow regulation in
muscle (cats).
03 (SGYB) HALASZ, NICHOLAS A, UNIVERSITY OF CALIFORNIA.
225 WEST DICKINSON STREET. SAN DIEGO. CALIF. Studies in lung
preservation (dogs).
-04 (CVB) HAAS, ERWIN, MT SINAI HOSPITAL. 1800 EAST 105TH
STREET. CLEVELAND. OHIO. Experimental renal and neurogenic hyper-
tension (human, animals).
.03 (CVA) LEAMAN, DAVID M, PENNSYLVANIA STATE UNIVERSIH,
DIVISION OF CARDIOLOGY, HERSHEY, PA. Narcotics and the circulation
(human, dogs. pigs, monkeys).
■04 (EXP) HARRIS, ALAN H, JOHNS HOPKINS UNIVERSITY. 720 RUT-
LAND AVENUE. BALTIMORE. MD. Circulatory effects of operant car-
diovascular control (baboons).
PROJECT NUMBER AND INVESTIGATOR ADDRESS
556
R01HL
ROIHl
ROIHL
ROIHL-
ROIHl
ROIHt
ROIHL
ROIHL-
ROIHL-
R01HL-
ROIHl
ROIHl
ROIHL-
ROIHL-
ROIHL.
ROIHl
ROIHl-
ROIHl-
ROIHL-
ROIHL
ROIHL-
ROIHl-
R01HL-
ROIHL-
ROIHl-
ROIHL
ROIHL
ROIHL-
ROIHL-
ROIHL
ROIHt
ROIHL-
R01HL
ROIHL
R01HL-
ROIHL-
■17963-04 (BIO) KHALIFAH, RAJA G, UNIVERSITY OF VIRGINIA, DEPART-
MENT OF CHEMISTRY, CHARLOTTESVILLE, VA. Human erythrocyte car-
bonic anhydrase.
17964-04 (HEM) PLOW, EDWARD F, SCRIPPS CLINIC & RESEARCH FDN
10666 N TORREY PINES ROAD, U JOLLA, CALIF. The alternate
pathway for fibrinolysis (human).
17967-04 (PHY) KUTCHAI, HOWARD C, UNIVERSITY OF VIRGINIA
PHYSIOLOGY DEPARTMENT. CHARLOHESVILLE, VA. Limiting factors in
oxygen uptake in the lung.
17969-04 (SGYB) NOLAN, STANTON P, UNIVERSITY OF VIRGINIA BOX
181, CHARLOTTESVILLE, VA. Function and structure of semilunar
valves (dogs).
17970-04 (AFY) ANDERSON. DAVID E, JOHNS HOPKINS UNIVERSITY 725
N WOLFE STREET. BALTIMORE. MD. Vascular effects of inhibitory
behavioral adaptations (dogs).
17973-04 (PTHA) BOOYSE, FRANCOIS M, RUSH-PRESBY-ST LUKES MED
CTR, 1753 W CONGRESS PKWY, CHICAGO, ILL. Cultured aortic en-
dothelial cells (human, cattle, dogs, swine).
-17974-03 (SGYA) SHAPIRO, ASCHER H, MASSACHUSEHS INST OF TECH
77 MASSACHUSEnS AVENUE, CAMBRIDGE, MASS. External pneumatic
compression in deep venous thrombosis (human)
-17976-18 (PC) MANSOUR, TAG E. STANFORD UNIVERSITY 300 PASTEUR
DRIVE, STANFORD, CALIF. Chemical agents and heart glycolytic en-
zymes (sheep).
■17993-04 (SGYA) INGELS, NEIL B, JR, PALO ALTO MED RESEARCH FDN
860 BRYANT STREET, PALO ALTO, CALIF. Ventricular dynamics from
surgically inserted markers.
17993-04 0001 (SGYA) STINSON, EDWARD B. Ventricular dynamics
from surgically inserted markers -Effects of aortocoronary bypass graft
surgery on ventricular function (human)
17993-04 0002 (SGYA) SCHROEDER, JOHN S. Ventricular dynamics
from surgically inserted markers-Left ventricle function in human car-
diac allograft.
17993-04 0003 (SGYA) ALDERMAN, EDWIN L. Ventricular dynamics
from surgically inserted markers-Effects of pharmacologic agents on
left ventricular dynamics (human).
-17993-04 0004 (SGYA) OEBUSK, ROBERT. Ventricular dynamics from
surgically inserted markers-Exercise training following coronary artery
bypass graft surgery (human).
•17993-04 0005 (SGYA) ALDERMAN, EDWIN L. Ventricular dynamics
from surgically inserted markers-Cardiac dimensions and dynamic
after mitral, aortic valve surgery (human)
■17993-04 0006 (SGYA) INGELS, NEIL B, JR. Ventricular dynamics from
surgically inserted markers-Atrial pacing in transplant patients
■17993-04 0007 (SGYA) INGELS, NEIL B, JR. Ventricular dynamics from
surgically inserted markers-Digitalis after coronary artery surgery
(human).
17993-04 0008 (SGYA) INGELS, NEIL B, JR. Ventricular dynamics from
surgically inserted markers-Exercise after coronary bypass (human)
17993-04 0009 (SGYA) INGELS, NEIL B, JR. Ventricular dynamics from
surgically inserted markers-Cardiovascular visualization in surgery of
growing heart (dogs).
17993-04 0010 (SGYA) INGELS, NEIL B, JR. Ventricular dynamics from
surgically inserted markers -Postoperative cardiovascular visualization
(human).
17995-04 (PBC) BUONASSISI, VINCENZO, UNIV OF CALIFORNIA SAN
DIEGO, BIOLOGY DEPT, C016, LA JOLU, CALIF. Cellular synthesis and
release of mucopolysaccharides (rabbits).
17998-04 (PHY) RENKIN, EUGENE M, UNIVERSITY OF CALIFORNIA DEPT
OF HUMAN PHYSIOLOGY, DAVIS, CALIF. Regulatory mechanisms in
blood circulation (dogs).
18002-03 (SGYB) ALTURA, BURTON M, SUNY-OOWNSTATE MEDICAL
CENTER, 450 CURKSON AVENUE, BROOKLYN, N Y. Circulatory shock
trauma and RE-system function (rats).
18003-05 (SSS) SMITH, THOMAS W, PETER BENT BRIGHAM HOSPITAL 721
HUNTINGTON AVENUE, BOSTON, MASS. Digitalis-Mechanism and rever-
sal studies (dog, sheep, duck, guinea pig, human).
18004-02 (BBCA) GHOSH, SANTIBRATA, NORTHWESTERN UNIVERSITY
303 EAST CHICAGO AVENUE, CHICAGO, ILL. Transport through arterial
wall-Biophysical aspects (rabbits).
18007-05 (PHY) REMMERS, JOHN E, UNIVERSITY OF TEXAS, PULMONARY
DIVISION, GALVESTON, TEX. Neural mechanisms controling motor act
of breathing (cats, human).
18010-04 (CVB) RENKIN, EUGENE M, UNIVERSITY OF CALIFORNIA, DAVIS
CALIF Capillary transport of large molecules (dogs sheep)
18012-04 (HEM) HARTMANN, ROBERT C, VETERANS ADMINISTRATION
HOSP, 13000 NORTH 30TH STREET, TAMPA, FU. Cellular defects in
nocturnal hemoglobinuria (human).
18015-03 (PHRA) ALTURA, BURTON M, S U N Y - DOWNSTATE MED CTR
450 CURKSON AVENUE, BROOKLYN, N Y. Pharmacologic studies on
vascular smooth muscle (dogs, rats).
18019-04 (CVB) MICHELAKIS, ANDREW M, MICHIGAN STATE UNIVERSITY
DEPARTMENT OF PHARMACOLOGY, EAST UNSING, MICH. The endocrine
kidney in hypertension (mice).
■18020-04 (CVA) COHN, JAY N, UNIVERSITY OF MINNESOTA, BOX 488
MINNEAPOLIS, MINN. Splanchnic hemodynamics in man
18022-03 (CVA) CHANG, HSIN-KANG, SUNY-AT BUFFALO, DEPT OF CIVIL
ENGINEERING, BUFFALO, N Y. Role of multicomponent diffusion in gas
exchange (avian eggs).
-18024-03 (CVA) FOX, IRWIN J, UNIVERSITY OF MINNESOTA, 424 MILLARD
HALL, MINNEAPOLIS, MINN. Regional myocardial flow and function
relationships (dogs).
•18027-03 (CVB) MICHELAKIS, ANDREW M, MICHIGAN STATE UNIVERSITY
DEPARTMENT OF PHARMACOLOGY. EAST UNSING, MICH. New vasoac-
tive factors and their role in hypertension (human, dogs rats)
18028-03 (TOX) SCHANKER, LEWIS S, UNIVERSITY OF MISSOURI 5100
ROCKHILL ROAD, KANSAS CITY, MO. Absorption of nonvolatile com-
pounds from the lung.
18030-04 (HEM) PUSZKIN, ELENA G, MONTEFIORE HOSPITAL & MED CTR
111 EAST 210TH STREET, BRONX, N Y. The role of contractile proteins
in platelets (human, rabbits),
18032-03 (CVB) SACHS, HOWARD G, UNIVERSITY OF ILLINOIS, 1853
WEST POLK, CHICAGO, ILL. Development of normal and myopathic
mammalian heart (hamsters).
ROlHt
ROIHL
ROIHl
ROIHL-
ROIHL
ROIHL
ROIHL-
ROIHL-
ROIHL-
ROIHl
ROIHl-
ROIHl-
ROIHl
ROIHL
ROIHl-
ROIHL-
ROIHL-
R01HL
ROIHL
ROIHL
ROIHL
ROIHL-
R01HL-
R01HL
R01HL-
ROIHl
ROIHL
R01HL-
R01HL-
■18038-03 (BIO) STONER, CLINTON D, OHIO STATE UNIVERSITY 1314 KIN-
NEAR ROAD, COLUMBUS, OHIO. Structure and function of heart
mitochondria (cattle).
18040-04 (SGYB) SCHUDER, JOHN C, UNIVERSITY OF MISSOURI SUR-
GERY DEPARTMENT, COLUMBIA, MO. Waveform dependency in defibril-
lation (calves).
18048-04 (BBCB) TSONG, TIAN Y, JOHNS HOPKINS UNIVERSITY 725
NORTH WOLFE STREET, BALTIMORE, MD. Dynamics of artificial and
biological membranes (human).
-18050-04 (CVB) GILBERT, ENID F, UNIVERSITY OF WISCONSIN 470 NORTH
CHARTER STREET, MADISON, WISC. Mechanisms of cardiovascular
teratogenesis (chick embryo) k embryo).
-18053-03 (PHY) WALKER, JOHN L, UNIVERSE OF UTAH, DEPARTMENT OF
PHYSIOLOGY, SALT UKE CITY, UTAH. Intracellular ionic activities in
heart muscle (frogs).
-18060-04 (CVB) KRAMSCH, DIETER M, UNIVERSE HOSPITAL, 75 E NEW-
TON STREET, BOSTON, MASS. Exercise and coronary atherosclerotic
heart disease (monkeys).
•18068-02 (HEM) LASKER, SIGMUND E, NEW YORK MEDICAL COLLEGE
FIFTH AVENUE AT 106 STREET, NEW YORK, N Y. Chemistry and activity
of homologous heparin fractions (rodents).
-18070-04 (CVA) KADOWITZ, PHILIP J, TUUNE UNIVERSE. 1430 TUUNE
AVENUE, NEW ORLEANS, U. Regulation of intrapulmonary airways and
vessels (human, animals).
18077-04 (PHY) BAGBY, ROLAND M, UNIVERSITY OF TENNESSEE DE-
PARTMENT OF ZOOLOGY, KNOXVILLE, TENN. Smooth muscle cell or-
ganization and Ca20 concentration control (chickens)
18080-03 (CVA) SHEPHERD, ALBERT P, JR, UNIVERSITY OF TEXAS 7703
FLOYD CURL DRIVE, SAN ANTONIO, TEX. Extrinsic control of intestinal
microcirculation (dogs).
18082-03 (HEM) HUTCHISON, VICTOR H, 730 VAN VLEET OVAL, NOR
MAN, OKU. Erythrocyte phosphates and vertebrate gas transport
(amphibians, reptiles).
■18084-03 (SGYB) AKUTSU, TETSUZO, TEXAS HEART INSTITUTE POST OF-
FICE BOX 20269, HOUSTON, TEX. Artificial heart and related problems
(calves).
18085-03 (PTHA) GUTSTEIN, WILLIAM H, NEW YORK MEDICAL COLLEGE
BASIC SCIENCE BUILDING, VALHALU, N Y. Neural factors in
atherogenesis (squirrel monkeys).
•18087-03 (CVB) WILDENTHAL, C KERN, UNIVERSITY OF TEXAS 5323
HARRY HINES BLVD. DALUS, TEX. Development and regression of car-
diac hypertrophy (rats, rabbits).
•18089-04 (PC) SCHUIZ, HORST H, CITY COLLEGE -CUNY COVENT
AVENUE & I38TH STREET, NEW YORK, N Y. Fatty acid metabolism in
heart and its regulation (swine, rats),
18094-04 (MET) NESS, GENE C, UNIVERSITY OF SOUTH FLORIDA, BOX 7
TAMPA, FU. Regulation of cholesterol biosynthesis (rats)
18095-04 (BIO) STONE, RICHARD A, VETERANS ADMINISTRATION HOSP
3350 U JOLU VILUGE DRIVE, SAN DIEGO, CALIF. Human dopamine^
beta-hydroxylase (also cattle).
18096-04 (SGYB) SWAN, KENNETH G, NEW JERSEY MEDICAL SCHOOL
100 BERGEN STREET, NEWARK, N J. Vasoactive agents in splanchnic
viscera (primates, dogs).
18097-04 (GMB) CONGER, JOHN D, UNIVERSITY OF COLORADO
MEDICINE DEPARTMENT, DENVER, COLO. Pathogenesis of acute renal
failure (rats).
•18102-02 (CVB) ULICK, STANLEY, VETERANS ADMINISTRATION HOSP 130
WEST KINGSBRIDGE ROAD, BRONX, N Y. Role of the adrenal cortex in
human hypertension.
■18118-04 (MCHA) MC MURRY, JOHN E, UNIVERSITY OF CALIFORNIA
THIMANN UBORATORY, SANTA CRUZ, CALIF. Total synthesis of cardiac
aglycones.
18143-03 (SGYA) WALLACE, HERBERT W, UNIVERSITY OF PENNSYLVANIA
19TH AND LOMBARD STREETS, PHIUDELPHIA, PA. Surgery and pulmo-
nary tissue alterations (dogs, rats, human).
■ 18144-03 (COM) ARTHUR, R MARTIN, WASHINGTON UNIVERSITY LINOELL
& SKINKER, ST LOUIS, MO. Preprocessor system for cardiograms
(human).
• 18145-03 (CVA) BANCHERO, NATALIO, UNIVERSITY OF COLORADO 4200
EAST NINTH AVENUE, DENVER, COLO. Oxygen transport mechanisms in
hypoxia (dogs, rats, rabbits).
■18148-04 (PHRA) PERLMAN, ROBERT L, HARVARD MEDICAL SCHOOL 25
. . , ., SHAHUCK STREET, BOSTON, MASS. Adrenal catecholamine secretion
18152-03 (PTHA) lORIA, ROGER M, VIRGINIA COMMONWEALTH UNIV
1200 EAST BROAD STREET, RICHMOND, VA. Vascular injury and
atherosclerosis (mice, coxsackievirus).
18156-02 (CVA) CHANDRAN, KRISHNAN B, TUUNE UNIVERSITY 1430
,., „ « ^V^ *^^""^' '^™ °'"-"'^^' ^ Hemodynamics in curved arteries
18157-04 (PTHA) DE DUVE, CHRISTIAN R, ROCKEFELLER UNIVERSITY
EAST 66TH STREET & YORK AVE, NEW YORK, N Y. Subcellular events
in atherosclerosis (human, rabbits, calves).
18163-04 (TOX) GOLDSTEIN, BERNARD D, NEW YORK UNIVERSITV 550
FIRST AVENUE. NEW YORK, N Y. Red cell membrane effects due to ox-
idizing agents.
18175-03 (EDO SLOME, CECIL, UNIVERSITY OF NORTH CAROLINA DEPT OF
EPIDEMIOLOGY, CHAPEL HILL, N C. Drug taking for hypertension in a
rural community
18176-02 (SSS) TSAI, JIR-SHIONG, NEW YORK UNIVERSITY 550 FIRST
AVENUE, NEW YORK. N Y. Effect of thyroid hormone on cultured car-
diac cells (rats).
18179-03 (BIO) SCHLISELFELD, LOUIS H, UNIVERSITY OF ILLINOIS 1853 W
POLK STREET. CHICAGO. ILL. Heart, platelet, and muscle myosins and
adomyosins (cattle).
■18181-04 (PC) SNYDER, FRED L, OAK RIDGE ASSOCIATED UNIVS P 0 BOX
117, OAK RIDGE, TENN. Surfactant metabolism -Alveolar cells and
lung disease (mice, rabbits).
18185-04 (GMB) BANERJEE, SHAILESH P, UNIVERSITY OF ROCHESTER
601 ELMWOOD AVENUE, ROCHESTER. N Y. Cardiac glycosides and diu-
retics-Role of NaO pump (dogs).
18186-04 (1MB) BENNETT, MICHAEL, BOSTON UNIVERSITY, 80 E CONCORD
STREET, BOSTON, MASS. Cardiac allografts in autologous radiation
chimeras (rats, dogs).
18190-03 (CVB) HODGES, MORRISON, HENNEPIN CNTY MEDICAL
CENTER, FIFTH AND PORTUND SOUTH, MINNEAPOLIS. MINN. Myocardi-
al blood flow in acute myocardial infarction (human, dogs).
557
•01Hl.ie»91-04 (CVA) AlIXANDU, A V. COLORADO STATE UNIVERSITY. DEPT /
PHYSIOLOGY & BIOPHYSICS. FORT COLLINS. COLO Models o( hypoxic
pulmonary hypertension (cnUle. minipits)
tOlMl-1 •199.03 (PHRA) ROSS, GORDON. UNIVERSITY OF CALIFORNIA, DEPART
MENT OF PHYSIOLOGY. LOS ANGELES. CALIF. Ellectj ot ions on vascu
lilt rBflctivitV
•01 Ml-1 8204-03 (CVB) EINIIO. STANLEY. UNIVERSITY OF MINNESOTA. 424 MIL
LARD HALL. MINNEAPOLIS. MINN Regional blood How in vital myocar
ditis (turkeys) „,
ROl HI- 18206-04 (MET) NEEIY. JAMES R, MILTON S HERSHEY MEDICAL CTR. OE
PARTMENT OF PHYSIOLOGY. HERSHEY. PA Regulation of metabolism
in otygen deficient hearts (rats)
P01 HI- 18208-04 (HEP) lA CEllE, PAUl I. UNIVERSITY OF ROCHESTER. SCHOOL
OF MED & DENTISTRY. ROCHESTER. N Y Center lor the study of blood
cell rheology . .. . ^ i
POIHl-l 8208-04 0001 (HEP) UCHTMAN. MARSHAU A. Center (or the study of
blood cell rheology Physiological basis of reversible erythrocyte shape
change (human, fiielly)
POlHl-18208-04 0002 (HEP) THOMPSON. BRIAN J. Center for the study of
blood cell rheology Holography of RBC shape (human).
POlHl-1 8208-04 0003 (HEP) KIRKPATRICK. FRANCIS H. Center for the study of
blood cell theology Bone marrow microcirculation (rats, mice).
POIHl-1 8208-04 0004 (HEP) UCHTMAN, MARSHALL A. Center for the Study of
blood cell theology Splenic mictocitculation (tats, mice)
POl HI- 18208-04 0005 (HEP) lACEUE. PAUl L. Center for the study of blood cell
theology-RBC defotmability and capillaiy flow intettelations (human.
mice).
POl Hl-1 8208-04 0006 (HEP) WEYMANN, HELMUT 0. Center fot the study of
blood cell theology-Analysis of flow in artetioles and capillaties
(human) .... . j
P01HH8208-04 0007 (HEP) KIRKPATRICK, FRANCES H. Center fot the study
of blood cell theology-RBC membrane protein (human).
R01HH8219.04 (MET) SIMONI, ROBERT 0. STANFORD UNIVERSITY. BIOLOGICAL
SCIENCES DEPT. STANFORD. CALIf Regulation of cholesterol metabol-
R01Hl-18226-oi"(BBCB) ASAKURA. TOSHIO. CHILDREN'S HOSPITAL. 34TH ST
AND CIVIC CENTER BLVD . PHILADELPHIA. PA. Mechanism of oxygen
supply to tissue (human, animals).
ROlHl-l 8235-03 (EDO CADY. lEE D, CARDIOPULMONARY UBORATORY, 222 N
GRAND AVENUE, LOS ANGELES. CALIF. Catdiovascular fitness and
other risk factors (human)
ROl Hl-1 8239-03 (NTN) MATHIAS, MEIVIN M, COLORADO STATE UNIVERSITY,
FOOD SCIENCE & NUTR DEPT, FT COLLINS. COLO. Dietary fat composi-
tion and ptostaglandin synthesis (tats).
ROI Hl-1 8245-03 (SSS) KOEHIER. KARl A, UNIVERSITY OF NORTH CAROLINA. DE-
PARTMENT OF PATHOLOGY. CHAPEL HILL. N C. Ttansition state analog
inhibitots of thrombin (human, cattle).
ROl Hl-1 8249-04 (HEM) SCHICK. PAUl K. MEDICAL COLL OF PENNSYLVANIA. 3300
HENRY AVENUE. PHILADELPHIA. PA. Isolation and identification ot
platelet membrane (human).
R01HH8253-03 (MCHB) SCHEUER. PAUl J, UNIVERSITY OF HAWAII. 2545 THE
MALL HONOLULU, HAWAII. Structure of the palytoxins.
ROl Hl-l 8255-04 (BBCB) FEIGENSON. GERAID W. CORNELL UNIVERSITY 254
CLARK HALL. ITHACA. N Y. Lipid-ptotein interactions and calcium
ROl Hl-1 8256-0 i'TbBCB)'"11MmER, PAUl H, AUBURN UNIVERSITY. DEPARTMENT
OF PHYSICS. AUBURN. ALA. Optical properties of platelets and etythto-
cvtes (tabbits. dogs, human).
R01HH82S8-04 (MET) MORGAN. HOWARD E. MILTON S HERSHEY MEO
"" CENTER. DEPT OF PHY, 500 UNIV DRIVE. HERSHEY. PA. Regulation of
protein degradation in heart (rats).
ROl Hl-1 8259-03 (PHRA) PRINTZ. MORTON P. UNIV OF CALIFORNIA SAI^ DIEGO,
DEPARTMENT OF MEDICINE, LA JOLLA, CALIF. Controlled inttatissue
release of prostaglandins.
ROl Hl-1 8260-04 (PHRA) MURAD, FERID, UNIVERSITY OF VIRGINIA. DEPT OF m-
TERNAL MEDICINE. CHARLOHESVILLE. VA, Cyclic nucleotide metabol-
ism in lung tissue (cattle).
ROl Hl-1 8272-03 (BBCA) DOWBEN. ROBERT M, UNIVERSITY OF TEXAS, 5323
HARRY HINES BOULEVARD. DALLAS. TEX. Heart adenyl cyclase complex
R01HH8280-03'"ivBT'DOBSON, JAMES G. JR, UNIVERSITY OF MAS-
SACHUSETTS. 55 LAKE AVENUE. NORTH. WORCESTER. MASS. Regula-
tion of cardiac conttactility and metabolism (rats).
ROl HI- 18284-04 (HEM) SEAMAN, GEOFFREY V, UNIVERSITY OF OREGON. 3181
S W SAM JACKSON PARK ROAD. PORTLAND. OREG. Aging etythtocytes-
Bio-tecognition and elimination (monkeys).
ROl Hl-1 8288-04 (SGYA) lEVITSKY, SIDNEY. UNIVERSITY OF ILLINOIS POST OF-
FICE BOX 6998, CHICAGO, ILL. Inttaopetative ptotection of the myocat-
ROI Hl-1 8292-04*" (PHYrP™N. ROIAND N. MEDICAL COLLEGE OF VIRGINIA,
BOX 608, MCV STATION, RICHMOND, VA. Vasodilation and mictovascu-
lat oxygen delivery (dog. hamstet).
ROl Hl-1 8304-03 (BBCB) RIESKE, JOHN S. 214 HAMILTON HALL, 1645 NE L
AVENUE, COLUMBUS, OHIO. FT-infrared spectroscopy of heart muscle
ROl Hl-1 8308-03 TcVA)VaRK,%uNG S. ALBERT EINSTEIN COLLEGE OF MED. 1300
MORRIS PARK AVENUE, BRONX, N Y. Comprehensive studies of mu-
cociliary transport (dogs), r-.-nu
ROl Hl-1 8309-04 (BBCB) MOFFAT. JOHN K. CORNELL UNIVERSITY, 252A CLARK
HALL, ITHACA, N Y. Oxygen transport -Hemoglobins with modified
hemes (horse).
P50HH8318-03 (SRC) CHOBANIAN, ARAM V. BOSTON UNIVERSITY. 80 E CON^
CORD STREET. BOSTON. MASS. Pathogenesis and complications ot
hypertension.
P50HL-1 831 8-03 0001 (SRC) CHOBANIAN, ARAM V. Pathogenesis and compli-
cations of hypertension -Core clinical program.
P50HI-1 83 18-03 0002 (SRC) KRAMSCH, DIETER M. Pathogenesis and complica
tions of hypertension-Core experimental animal facility (tats, tabbits).
P50HI-1 831 8-03 0003 (SRC) GAVRAS, HARAIAMBOS P. Pathogenesis and
complications of hypertension -Core biochemical laboratory.
PSOHl-l 831 8-03 0004 (SRC) MEIBY, JAMES C. Pathogenesis and complications
of hypertension-Steroid and renin profiles in hypertension (rats.
human).
PROJECT NUMBER AND INVESTIGATOR ADDRESS
PSOHl-1 83 18-03 0007 (SRC) AllXANOIR, EDWARD A. P.thoi.n..i. .nd com
plications of hypertension Humoul factors and renal lunclion in n
penmental hypertension (rats)
P50HI-1 83 18-03 0009 (SRC) MEIBY, JAMIS C. Pathogenesis and complic.lion.
ol hypertension Ihe mineialocorticoid hypertensive syndrome in man
P50Hl.18318.03 0010 (SRC) HOOD. W.UIAM 8. JR. ''•"""'•"T „'h .'nTl
cations of hypertension Hemodynamics in mineialocorticoid and km
renin hypertension (human)
P50H1.1 83 18-03 0011 (SRC) CHOBANIAN. ARAM V. Pathogenesis and comph
cations of hypertension Adrenergic function Renin and mmeralocorti-
cold activity (human)
P50HI-1 83 18-03 0012 (SRC) JENKINS. C DAVID. Pathogenesis and conjplic.
tions of hypertension Behavioral factors in hypertension (human)
PSOHl-l 83 18-03 0013 (SRC) lEVINSKY. NORMAN O. Pathogenesis and comph
cations of hypertension Humoral factors and renal function in human
hypertension . _,
PSOHl-l 83 18-03 0014 (SRC) CHOBANIAN, ARAM V. Pathogenesis and com pi ■
cations of hypertension Arterial metabolism and atherogenesis Cal,
rabbit) . ...
PSOHl-l 83 18-03 0015 (SRC) BRECHER, PETER I. Pathogenesis and complica^
tions of hypertension Cultured smooth muscle cells and microvessel
metabolism (mammals)
PSOHl-l 83 18-03 0018 (SRC) HOOD, willlAM B, JR. Pathogenesis and compli
cations of hypertension Plasma renin activity in chronic ischemic
heart disease (human)
PSOHl-l 83 18-03 0019 (SRC) GAVRAS, HARAIAMBOS. Pathogenesis and com
plications of hypertension -Renin angiotensin system in blood pressure
regulation (human, tat. dog)
ROl Hl-1 8321 -03 (SGYB) GARDNER, RICHARD A, WASHINGTON UNIVERSITY. BOX
1185. ST LOUIS, MO Fluid sheat ot magnetic alignment ot blood com-
PS0Hl-18323-04'"'(SR"cV^irRAGH, JOHN H. CORNELL UNIVERSITY MEDICAL SCH.
1300 YORK AVENUE. NEW YORK, N Y SCOR hypertension centet
PSOHl-l 8323-04 0011 (SRC) lARAGH. JOHN H. SCOR hypertension centet- En-
doctine ptofiling on a selected notmal population (human).
PSOHl-1 8323-04 0012 (SRC) lARAGH. JOHN H. SCOR hypertension center-
Renin as a risk factor (human)
PSOHl-1 8323-04 0033 (SRC) SEAIEY. JEAN E. SCOR hypertension center-Core
laboratoiy-Renin. aldostetone and btadykinin methodology
P50HI-1 8323-04 0034 (SRC) lARAGH, JOHN H. SCOR hypertension centet-
Core-Data management.
PSOHl-l 8323-04 0035 (SRC) ALDERMAN, MICHAEL H. SCOR hypertension
center -Control of high blood pressure at the work site
PSOHl-l 8323-04 0037 (SRC) NEW, MARIA I. SCOR hypertension center-
Adrenocortical factors in childhood hypertension.
PSOHl-l 8323-04 0038 (SRC) UlICK, STANLEY. SCOR hypertension center-Unk-
nown adrenocortical mechanisms in hypertension (human).
PSOHl-l 8323-04 0041 (SRC) lEVITT, MORTON. SCOR hypertension center-Mea-
surement of sympathetic response in hypertensive patients.
PSOHl-l 8323-04 0042 (SRC) CHIEN. SHU. SCOR hypertension center--Blood
viscosity and blood volume in hypertensive disease (human, dog).
PSOHl-l 8323-04 0043 (SRC) WEBER. MICHAEL A. SCOR hypertension center-
Phatmacology-Renin-aldostetone mechanisms in essential hyperten-
sion (human).
PSOHl-1 8323-04 0044 (SRC) CASE, DAVID B. SCOR hypertension centet-An
giotensin blockade to identify angiotensin 11 factor in hypertension
(human).
PSOHl-l 8323-04 0045 (SRC) SEAIEY, JEAN E. SCOR hypertension center -Labora-
tory ptogtams-Ptotenin (human).
PSOHl-1 8323-04 0046 (SRC) NIARCHOS. ANDREAS D. SCOR hypertension
centcr-Cotonaty artety bypass surgery-Associated hypertension
(human).
PSOHl-l 8323-04 0047 (SRC) CASE. DAVID B. SCOR hypertension center-Trans-
cendental meditation and self-hypnosis-Hypertension treatment
R01Hl.18328-03TvA) COHEN, JULES, UNIV ROCHESTER MEDICAL CENTER, 601
ELMWOOO AVENUE, ROCHESTER, N Y. Hemoglobin function and tissue
oxygenation (human, dogs).
ROl Hl-1 8333-05 (HEM) WESSIER, STANFORD, NEW YORK UNIVERSITY, 550
FIRST AVENUE, NEW YORK. N Y. Thtombogenesis and hemostatic
balance (tabbits. human). „„„„„, ,.,r
ROl Hl-1 8338-04 (CVA) BING, OSCAR H, BETH ISRAEL HOSPITAL. 330 BROOKLINE
AVENUE, BOSTON, MASS. Computer feedback study of cardiac muscle
ROl Hl-1 8340-04""pTh'a) BARAJAS, LUCIANO. HARBOR GENERAL HOSPITAL,
1000 W CARSON STREET, BOX 22, TORRANCE, CALIF. Electron
microscopy of the juxtaglomerular apparatus (tats).
ROIHI-18351-03 (PHY) NATTIE. EUGENE E. DARTMOUTH MEDICAL SCHOOL. DEPT
OF PHYSIOLOGY, HANOVER, N H. Btain metabolism, acid-base balance,
and tespiration.
R01 HL-1 8371 -03 (CVA) JURATSCH. CRAIG E, HARBOR GENERAL HOSPITAL. 1000
WEST CARSON STREET. TORRANCE. CALIF. Pulmonary hypertension and
ventilation pathophysiology (dogs).
R01 Hl-1 8398-04 (CVB) BOINEAU, JOHN P, VETERANS ADMINISTRATION HOSP.
CARDIOLOGY RESEARCH (151). AUGUSTA. GA. Mechanisms of delayed
and asymetric ventticulat conduction (human, dogs).
R25HI-1 8406-03 (HBP) ROSENSTOCK, IRWIN M. UNIVERSITY OF MICHIGAN.
1420 WASHINGTON HEIGHTS. ANN ARBOR. MICH. Adherence to hyper-
tensive medical regimens (human).
R25HI-1 84 14-03 (HBP) EARP. JO ANNE. UNIVERSITY OF NORTH CAROLINA.
SCHOOL OF PUBLIC HEALTH. CHAPEL HILL. N C. Hypertension-Family
strategies for patient adherence.
R25HI-1 84 18-03 (HBP) CAPIAN. ROBERT D. UNIVERSITY OF MICHIGAN, INST FOR
SOCIAL RESEARCH. ANN ARBOR. MICH. Role of a supporting partner
in adherence (human).
R25HI-1 8424-03 (HBP) CHADWICK. JOSEPH H. STANFORD RESEARCH IN
STITUTE. 333 RAVENSWOOD AVENUE. MENLO PARK. CALIF. Blood ptes-
sutc education in an industtial setting (human).
ROl Hl-1 8426-04 (CVB) NAVAR. lUIS G. UNIVERSITY OF AUBAMA. UNIVERSITY
STATION. BIRMINGHAM. ALA. Regulation of tenal hemodynamics
(dogs).
ROl Hl-1 8435-03 (HEM) SEEGERS. WAITER H, WAYNE STATE UNIVERSITY. 540
EAST CANFIELD. DETROIT, MICH. Ptoperties of thtombin and Ac-globu-
lin (human, animals).
PROJECT NUMBER AND INVESTIGATOR ADDRESS
ROl Hl-l 8441-03 (BBCB) HOEVE. CORNEUS A, TEXAS A & M UNIVERSITY DE
TMENT OF CHEMISTRY, COLLEGE STATION, TEX g!S r
polymers acting as elastin substitutes
ROI HH 8454-03 (AFY) JAMES, FREDERICK W, CHILDREN'S HOSPITAL ELUND &
K?;er.^,^,e:'"'^^'^^'' ""'o- «--' -'^'« 'S *
R01Hl-,8456.03(EDC)F.XLER DAVID E. UNIVERSITY OF TEXAS, 5323 HARRY
aTolescents Cardiovascular follow-up of hypertensive
RO.Hl.18460-01 (SGYB) WAKABAYASHI. AKIO. UNIVERSITY OF CALIFORNIA OE-
themv cJh"' TZ\ f*"' '""'^ "' "'o'""^^" hypoperj n on
the myocardium (rabbits).
ROl Hl-1 8467-03 (CVA) COFFMAN, JAY D. UNIVERSITY HOSPITAL 75 EAST NEW
Kaynaud s disease (human)
ROl Hl-1 8468-03 (CVB) GREENFIEID. JOSEPH C, JR, DUKE UNIVERSITY POST
OFFICE BOX 3246. DURHAM, N C. The distribution of flow in t
myocardium (dog. pig)
ROl Hl-1 8473-04 (PTHA)HEPTINSTAU, ROBERT H, JOHNS HOPKINS HOSPITAL
0 NORTH BROADWAY, BALTIMORE, MD. Genesis of atherosclerotic I :
sions (human, mules)
ROl Hl-1 8489-03 (PHY) PREWITT, RUSSELl L, JR, UNIVERSITY OF TENNESSEE
UNION AVENUE (NA 427., MEMPHIS. TENN. Hemodynarlic i'ter :
tions of vasoactive chemicals (rats)
ROl Hl-1 8492-03 (CVB) GOUID, KENNETH I, SEAHLE V A HOSPITAL 4435
BEACON AVE, S, SEAHLE, WASH. Measurement of regional coronary
flow reserve (human, dogs)
ROlHl-18502-03 (HEM) KOSOW, DAVID P, BLOOD RESEARCH LABORATORY 9312
Ola .Im^'^Th "T' '™''''' "°- ^"'Vmatic regulation o
platelet function (human)
ROl Hl-1 8507-03 (HEM) HATHAWAY, WIlllAM E, UNIVERSITY OF COLORADO
SLTa:..™'''^^^^^'^°^°-^''"'--"--o'^'-h°;
R01HI.I8S16-03 (BBCB) FREDERIKSEN. DIXIE W, VANOERBILT UNIVERSITY DEPT
OF BIOCHEMISTRY, NASHVILLE, TENN. Atherosclerosis and t arte,"
contractile proteins (pigs, rabbits)
ROl Hl-l 85 1 7-03 (CVB) PRIOIA, DONALD V, UNIVERSITY OF NEW MEXICO 915
ROl Hl-l 85 1 9-03 (SGYB) ANDRADE. JOSEPH D, UNIVERSITY OF UTAH INST FOR
hToc^^VHT;.'*'' "•*' '"'■ ™"- A'"-'" endoLll an
hemocompatibihty (human, dog, cattle, rabbit)
RO 1 Hl-l 8526-03 (AIY) NEWBAIL. HAROID H, GOOD SAMARITAN HOSPITAL 5601
ROl Hl-l 8527-03 (AFY) GOllNICK, PHIIIP D, WASHINGTON STATE UNIVERSITY
of °/,T' ?"' "" "'"• '"'"'"*■ «*SH. Subcellular response
of heart to functional overload (hamsters rats)
ROIHl.18533-03 (BBCB) TOONEY, NANCY M, POLYTECHNIC INST OF NEW YORK
333 JAY STREET, BROOKLYN, N Y. Microcrystalline and c™e
fibrinogen (cattle, bacteria) '■■yiiaiiine
ROl Hl-l 8535-03 (VR) D'ALESSIO, DONN J, STATE LABORATORY OF HYGIENE 465
HENRY MALL, MADISON, WIS. Epidemiology and course of viral myoer
icarditis (human).
ROIHl-18537-04 (CVA) COBB FREDERICK R, VETERANS ADMINISTRATION HOSP,
iLlVT ^™^,^7' """"*"■ ** <=• "'8'°"^' "I""" 'low after acute
myocardial injury (dogs)
ROIHl-18538-03 (CVB) BAILEY. JOHN C, INDIANA UNIVERSITY IICO WEST
MICHIGAN STREET INDIANAPOLIS. IND. The role of e^ltonus in H s
Purkin/e function (dog)
ROI Hl-l 855 1 -03 (HEM) KIRKPATRICK, FRANCIS H, JR, UNIVERSITY OF
ROCHESTER. DEPT OF RAD BIOL 4 BIOPHYS, ROCHESTeT N Y Spec
Dn.u, ,. '""• actm. hpid and red cell membrane structure
ROI Hl-l 8553-03 (MET) GRUENSTEIN, ERIC I, UNIVERSITY OF CINCINNATI 231
BETHESDA AVENUE. CINCINNATI. OHIO. Membrane def cts in f m a
hypercholesteremia (human)
ROIHl-18554.03 (BIO) SCHAFFER. STEPHEN W, LEHIGH UNIVERSITY DEPART-
MENT OF CHEMISTRY. BETHLEHEM, PA. Taurine metabolism in mam-
mahan heart (rodents, cattle, swine)
R0,Hl.I8560.03 (AFY) SANDERS, TOMMY M, UNIV OF CALIFORNIA, SAN DIEGO,
rmmiature'^sw^er' "'' '"'"'"''"'" ""'">''""' '° ^«-"
ROlHl.18561-03 (PBC) WILKINSON, J SIDNEY, UNIVERSITY OF MISSISSIPPI
0 NORTH STATE STREET, JACKSON, MISS. Radioimmunoa To
angiotensinogen (human) <«>^»<ij oi
ROI Hl-1 8567-03 (BIO) DE VElllS, JEAN S, UB OF NUCLEAR MED AND RAD BIO
z:^,:^ir ' '-'- ^-"-'^^ - '°^ -'-^-
POIHl-18574-03 (HEP) IINDGREN, FRANK T, UNIVERSITY OF CALIFORNIA
biomedical applications.
POIHl.,8574-03 0001 (HEP) LINDGREN, FRANK T. Lipoprotein methodology and
unl ! apphcations-Ultracentrifugal and electrophoretic
lipoprotein methodology -Applications
POlHl-18574-03 0004 (HEP) FORTE, GERTRUDE M. Lipoprotein methodology
and biomedical applications-Fine structure and metabolism of
hpoproteins-EM studies (guinea pigs)
P01HI-I8S74.03 0005 (HEP) NICHOLS, AlEX V. Lipoprotein methodology and
P0lHl-i««^ JlTJ^f applications-structure and function of lipoproteins.
POIHH 8574-03 0006 (HEP) KRAUSS, RONAID M. Lipoprotein methodology and
biomedical applications-Lipoprotein transformation, lipolytic enzymes,
diet and lipid lowering agents
POIHl.,8575-03 (HEP) BOHR DAVID F, UNIVERSITY OF MICHIGAN, 7710 MEDICAL
hypertensilln Mechanisms of vascular changes in
POlHl-18575.03 0001 (HEP) BOHR, DAVID F. Mechanisms of vascular changes
m^hypertension-Arteries and resistance vessels in hypertension (pigs,
POIHl-18575-03 0002 (HEP) GREKIN, ROGER J. Mechanisms of vascular
m hvo^r..'" ^'"'f'<«"f'»"-En'i''"ines, electrolytes, and hemodynamics
in hypertension (pigs)
POIHl-18575-03 0005 (HEP) MAIVIN, RICHARD I. Mechanisms of vascular
changes in hypertension-Renin synthesis in normotensive and hyper-
tensive pigs (also rats, dogs).
558
PO, Hl-l 8575-03 0006 (HEP) RANDAll, OTEIIO S. Mechanisms of vascular
changes in hypertension -Evaluation of arterial compliance in hyper-
tension (human, pigs)
POI Hl-l 8575-03 0007 (HEP) JOKEIAINER, PENTTI T. Mechanisms of vascular
ch^anges in hypertension-Microscopy of hypertensive arterial lesions
POI Hl-1 8575-03 0009 (HEP) BOHR, DAVID F. Mechanisms of vascular changes
in hypertension -Administrative core
POI Hl-l 8575-03 0010 (HEP) BOHR, DAVID F. Mechanisms of vascular changes
in hypertension -Hypertensive pig Core
POI Hl-1 8575-03 0011 (HEP) GREKIN, ROGER J. Mechanisms of vascular
»„.... changes in hypertension-Chemistry laboratory core facility
POlHl-l 8575-03 0012 (HEP) JOKEIAINER. PENTTI T^^Mechanisms of vascular
changes in hypertension -Anatomy core facility
POI Hl-l 8575-03 0013 (HEP) SCHORK, MICHAEL ANTHONY. Mechanisms of
""•^"^^ changes in hypertension-Biostatistical core
POI Hl-I 8576-03 (HEP) DOOIITTIE, RUSSEll F, UNIV OF CALIFORNIA SAN DIEGO
DEPARTMENT OF CHEMISTRY. U JOLi;*. CALIF. Thrombosis reS
program project.
POI Hl-l 8576-03 0001 (HEP) BERNSTEIN, EUGENE F. Thrombosis research pro-
gram project-Platelet damage from physical forces and artificial sur-
faces (human).
POI Hl-1 8576-03 0002 (HEP) DOOUTTIE, RUSSEll F. Thrombosis research pro-
gram project-Molecular basis of fibrin formation (human, cattle
lamprey). >•<■"■«.
POI Hl-1 8576-03 0003 (HEP) GOODMAN, MURRAY. Thrombosis research pro-
gram project -Biocompatible materials
POI Hl-1 8576-03 0004 (HEP) HARPER, ElVIN. Thrombosis research program pro-
PoiMi i««,i. „,"^;„ ^^"'"" '"'' "'"™' °' "collagen-platelet interaction
POlHl-18576-03 0005 (HEP) HOUGIE. CECIL Thrombosis research program pro-
ect-Molecuar basis of von Willebrands disease and hemophilia
(human, cattle)
POI Hl-1 8576-03 0007 (HEP) RAPAPORT, SAMUEl I. Thrombosis research pro-
gram project-Relationships between coagulability and thrombosis
(human, animals).
P0IHl.18576.03 0009 (HEP) HOUGIE, CECIL Thrombosis research program pro-
'"'■"^'"'"^ "* '^"^'O' VII 'l'""'^"' fabbits, cattle)
POlHl-18576.03 0010 (HEP) BERNSTEIN. EUGENE F. Thrombosis research pro-
POIHI 1857* o, '^n. wL'I;."""*'"" "* "on-thrombogenic materials (cattle).
POI Hl-I 8576-03 0011 (HEP) HARPER. ElVIN. Thrombosis research program pro-
POlHi in^T* «,"«^?r, *'" '"" """'" *""'^''°" "'""'="■ ""!«■ rabbits).
POI Hl-I 8576-03 0012 (HEP) DOOUTTIE, RUSSEll F. Thrombosis research pro-
pn.ui .».,.. - *'^'" P'Oject -Synthetic anticoagulant and thrombolytic agents (dogs)
POI Hl-l 8576-03 0013 (HEP) MO«FD ircMiuc'ru .. tu ''"- '■ecini luugs).
«u I o yncrj iviosER, KENNETH M. Thrombosis research pro-
gram project-Early warning and monitoring test systems in throm-
botic disease (human).
POIHl-18576-03 0014 (HEP) WOHL HERBERT. Thrombosis research program
project-Immunology core
P01H1.18S76-03 0015 (HEP) DOOUTTIE, RUSSEU F. Thrombosis research pro-
gram project-Major equipment core
POI Hl-l 8576-03 0016 (HEP) DOOUTTIE, RUSSEll F. Thrombosis research pro-
gram project-Radiochemistry core
POI Hl-I 8577-03 (HEP) SCANU ANGEIO M, 950 EAST 59TH STREET. CHICAGO
»„.^. ILL Lipoproteins -Cell surface interactions.
POIHl-1 8577-03 0001 (HEP) SCANU, ANGEIO M. Lipoproteihs-Cell surface in-
P01Hl-18577-03';r3"rH ;TKEZDrTER;N« j''T'°'''? '" T" "" ""'■
foXT v. : '^^^°^' PERENCZ J. Lipoproteins-Cell surface In-
branes"" ''"''' *'""''"*^ '" ''P°P™feins and cell mem-
POIHl-,8577-03 £o4 (HEP) HEINR.KSON, ROBERT L Lipoproteins-Cell surface
nteractions- Analysis and chemical modification of proteins in lipid
transport (human, dogs) '^
POlHl-18577-03 0005 (HEP) KAISER, EMU T. Lipoproteins-Cell surface interac-
ments " "PoUPoproteins and apoliprofein frag-
P0IHl-I8577-03^C.0«. (HE^ SCANU. ANGEIO M. Lipoproteins-Cell surface in-
"'"■'""■"irtirc^e^farror- "°"" '■ ^'-"^^-^- --
ROl Hl-I 8579-03 (CVB) NASJIETTI. ALBERTO. MEDICAL COLLEGE OF WISCONSIN
N 15TH STREET, MILWAUKEE, WIS. Vasoactive h r! nes and
RoiHi ,«.... „, ? " "'"'"" "«"'=*'''" '"085. rats, rabbits).
R0,HL.I8584.03 (HEM, HEUUMS. JESSE D. RICE UNIVERSITY, POST OFFICE BOX
R0IHl-.8586.03;(L^E:rrKli"DrEl°lSN's';^LrR^^
^„,„^ L:=^=-Sn)"^^--"'--Ssi^
ROl Hl-I 8589-03 (DBR) WIIUAMS. REDFORD B. JR. DUKE UNIVERSITY POST OF
diac arrest (dogs, monkeys)
ROl Hl-l 8593-03 (BIO) PINNEU, SHELDON R. DUKE UNIVERSITY BOX in-;
"r^^r'"' ' ' ^^^^-'^ of"S'Valve^°:il,^a;:^
R01Ht.l8S98-03 (PHRA) OKITA. GEORGE T. NORTHWESTERN UNIVERSITY 303 E
d^iSaS"' ^"'"^°' '^^- «°'^ °' "^' K-ATParSro^
ROlHl-18599.02 (PHRA, ^OJ^ANI. PITAMBAR. UNIVERSITY OF MIAMI, POST OF-
™ophores(dogs,"' '"'' '"' '"'""'''"^" "^'^^o'^^^ »'
ROI Hl-I 8601 -01 (PHRA) WAKADE, ARUN R, S U N Y DOWNSTATE MEDICAI PTR
450 CURKSON AVENUE, BROOKLYN. N Y. ReSon of u otran !
mitter release by adenosine (rats) leu.oirans
ROIHl-18606-04 (CVA, EFFROS, RICHARD M, HARBOR GENERAL HOSPITAL 1000
WES CARSON STREET. TORRANCE. CALIF. Pathogenesis and meae
on,^. ,..^ >"«"' Of pulmonary edema (human, rabbits, dogs)
ROIHl-18607-03 (PHRA) GERTNER, SHELDON B, COLLEGE OF MED 4 DENTIS-
TRY, 100 BER(^EN STREET. NEWARK, N J. Metabolic and drug s ud ies
on experimental fat embolism (mice)
R0IHI-I86I0-03 (CVB, SUBBIAH, RAVI M, MAYO FOUNDATION, 200 FIRST
STREET SW. ROCHESTER. MINN. Early intervention of age related a -
terial changes (pigeon).
MIHt
ROIHl
ROIHl
ROIHL-
ROIHl-
ROIHL-
R01HL-
ROIHt
ROIHl
ROIHl-
ROIHl-
ROIHl-
ROIHL
ROIHl-
POIHL-
POIHl-
POIHl-
P01HL
P01HL-
P01HL-
POIHL-
POIHl'
P01HL
POIHL-
P01HL-
P01HL-
P01HL-
POIHL
POIHl
POIHl-
R01HL
ROIHL
ROIHL-
ROIHl-
R01HL
ROIHL
ROIHL-
S59
1t6l3-03 (••€•) ORIASiR. MARION L, UNIVERISITY OF WISCONSIN,
1805 UNOfN DRIVE, MADISON, WIS Ihin liismenl conliol ol heart
conltaction (cattle)
ia6l8.04 (HEM) WUiPPiR. KIRK O, UNIVERSITY Of OREGON, 3181 S W
SAM lACKSON PARK RD. PORTLAND, OREG. Puridcation and lunclion
ol human HMW kininogen
I 86 1 9-03 (BBCA) FfiNEY. ROBERT E, UNIVERSITY OF CALIFORNIA. 3450
CHEMISTRY ADDITION, DAVIS. CALIF Transleinn iron bindini and
Itansport ptopeities (chicken, fabbit, human)
18623-H (BBCB) SMALL, DONALD M. BOSTON UNIV SCHOOL OF
MEDICINE, 80 EAST CONCORD ST, BOSTON. MASS Physical chemistry
ot biologically active lipids (bacteria, plant, cattle, human)
18624-03 (CVB) WONO. PATRICK V, ALBANY MEDICAL COLLEGE. 47 NEW
SCOTLAND AVENUE. ALBANY. N Y Study ot kinins in hypertension and
other diseases (human)
18625-03 (PC) EISENSTEIN, REUBEN, NORTHWESTERN UNIVERSITY. 303
EAST CHICAGO AVENUE. CHICAGO. ILL Organuation ol arterial ground
substance (cattle)
18629-04 (CVB) TOMANEK, ROBERT J, UNIVERSITY OF IOWA. DEPART
MENT Of ANATOMY. IOWA CITY. IOWA. Influence ol aging and hyper-
tension on the myocardium (rats)
18630-03 (CVA) NEW/Ell, JONATHAN C, RENSSEUER POLYTECHNIC
INST. BIOMEDICAL ENGINEERING CTR, TROY. N Y Pulmonary
hemodynamics in atelectasis and hypoxia (dogs)
18631-03 (PTHA) MC CAILISTER, LAWRENCE P, PENNSYLVANIA STATE
UNIVERSITY. 500 UNIVERSITY DRIVE. HERSHEY, PA Ultrastructural cor
relates of myocardial ischemia (rats, swine)
18632-02 (SSS) HIGGINS, MILIICENT W, UNIVERSITY OF MICHIGAN, 109
OBSERVATORY STREET, ANN ARBOR. MICH Epidemiologic study of
chronic lung disease
18634-03 (BBCA) VINOGRADOV, SERGE N, WAYNE STATE UNIVERSITY.
540 E CANFIELD. DETROIT. MICH Quarternarv structure of erythro and
chlorocruorins (invertebrates),
18636-02 (NTN) FEIOMAN, ELAINE B, MEDICAL COLLEGE OF GEORGIA.
AUGUSTA. GA, Fatty acids and cholesterol transport (rats)
18639-03 (SGYB) NOSE, YUKIHIKO, CLEVEUND CLINIC FOUNDATION.
9500 EUCLID AVENUE. CLEVELAND. OHIO, Human anatomy for cardiac
prostheses (human)
.18644-03 (SGYA) SAUVAGE, LESTER R, PROVIDENCE MEDICAL CENTER.
528 ■ 18TH AVENUE, SEATTLE, WASH, Prosthesis for aortocoronary
bypass (dogs, baboons), „_.„-,
.18645-03 (HEP) ROSS, RUSSELL, UNIVERSITY OF WASHINGTON, DEPART-
MENT OF PATHOLOGY, SEAHLE, WASH. Biology of the artery wall and
atherosclerosis.
-18645-03 0001 (HEP) ROSS, RUSSELL. Biology of the artery wall and
atherosclerosis-Primate arterial smooth muscle and atherosclerosis,
18645-03 0003 (HEP) BORNSTEIN, PAUL. Biology of the artery wall and
atherosclerosis-Synthesis of connective tissue proteins by smooth
muscle cells (human, monkeys)
.18645-03 0004 (HEP) PARKER, FRANK. Biology of the artery wall and
atherosclerosis-Human arterial smooth muscle cell and lipoprotein in-
teraction,
■ 18645-03 0005 (HEP) SCHWARTZ, STEPHEN M. Biology of the artery
wall and atherosclerosis-Effects of atherosclerosis risk factors on en-
dothelium of the primate,
-18645-03 0006 (HEP) HARKER, LAURENCE A. Biology of the artery wall
and atherosclerosis-The platelet and atherosclerosis (monkeys,
baboons).
18645-03 0007 (HEP) HAZ2ARD, WILLIAM R. Biology of the artery wall
and atherosclerosis -Lipoprotein metabolism in subhuman primates.
.18646-03 (HEP) RUSSELL, PAUL S, MASSACHUSETTS GENERAL HOSPITAL,
32 FRUIT STREET, BOSTON, MASS. Studies basic to heart transplanta-
tion.
18646-03 0001 (HEP) COSIMI, A BENEDICT. Studies basic to heart
transplantation-Individualized regulation of immunosuppression (dogs,
rats).
■ 18646-03 0002 (HEP) COSIMI, A BENEDICT. Studies basic to heart
transplantation-Detection of rejection (dogs).
-18646-03 0003 (HEP) COSIMI, A BENEDICT. Studies basic to heart
transplantation-Host responses to xenografts (rodents, rabbits).
18646-03 0004 (HEP) RUSSELL, PAUL S. Studies basic to heart transplan-
tation-Presensitization-Detection, incidence and clinical significance,
18646-03 0006 (HEP) RUSSELL, PAUL S. Studies basic to heart transplan-
tation-Reduction or elimination of existing presensitization (human,
animals).
.18646-03 0008 (HEP) DAGGETT, W1LLARD M. Studies basic to heart
transplantation-lmmunophysiology and early detection of rejection
(dogs). . t ^
■ 18646-03 0009 (HEP) MCCLUSKEY, ROBERT. Studies basic to heart
transplantation-Pathologic aspects of cardiac allograft rejection
(sheep, dogs).
18646-03 0010 (HEP) AUSTEN, W GERALD. Studies basic to heart trans
plantation-Development and study of a heart preservation chamber
(dogs, sheep).
18647-03 (CVA) ACOSTA, DANIEL, JR, UNIVERSITY OF TE)(AS. COLLEGE
OF PHARMACY. AUSTIN, TEX, Ischemic myocardial injury in cultured
heart cells (rats).
18650-03 (HEM) CHESNEY, CAROLYN M, UNIVERSITY OF TENNESSEE.
800 MADISON AVENUE. MEMPHIS, TENN. Platelet collagen interaction
(human).
18657-03 (PHRA) POWELL, WILLIAM J, JR, MASSACHUSETTS GENERAL
HOSPITAL. FRUIT STREET. BOSTON. MASS Pharmacologic studies on
neurogenic digitalis effects (human, cats, dogs),
18660-03 (BBCA) HUESTIS, WRAY H, STANFORD UNIVERSITY, DEPART-
MENT OF CHEMISTRY, STANFORD, CALIF. Neurotransmitter receptors in
human erythrocytes.
18672-03 (HEM) MC INTIRE, LARRY V, RICE UNIVERSITY, POST OFFICE
BOX 1892, HOUSTON, TEX. Dynamic studies of clot structure formation
(human).
• 18676-03 (PHY) POLLACK, GERALD H, UNIVERSITY OF WASHINGTON, DEPT
OF ANESTHESIOLOGY RN-10, SEAHLE. WASH. Myocardial sarcomere
mechanics (rat).
18679-04 (SSS) POWERS, JAMES C, SCHOOL OF CHEMISTRY, GEORGIA
INST OF TECHNOLOGY, ATUNTA, GEORGIA, Synthetic protease inhibi-
tors.
ROIHL-18682
ROlHL-18683
R01HI-1S687
ROIHL-18692
R01HI-1870S
POIHl-18708
P01HL-I8708
POIHl-18708-
POIHl-18708-
POlHL-18708-
POIHl-
POIHL-
POIHL-
ROIHL
18708
18708
18708-
■ 18710
R01HI-18711-'
ROlHl-18712
R01HL-18714
ROlHL-18715
ROlHL-18718
R01HL-18723
R01HL-I8725
R01HL-18730
R01HL-18731
R01HL-18736
ROIHL-18737
R01HL-18738
R01HL-18744
ROlHL-18746
ROlHl-18749
ROIHl
ROIHl
ROIHl-18769
ROlHL-18776
ROlHL-18783
ROIHl-18793
PROJECT NUMBER AND INVESTIGATOR ADDRESS
03 (BIO) JUNOMANN, RICHARD A, NORIHWfSIERN UHlVfRSIIY,
303 EAST CHICAGO AVfNUf, CHICAGO, III Protein kinaw and
cholesterol metabolism in aorta (rabbiti)
■03 (EDO HIRSHFELO, JOHN W, JR. UNIV Of PENNSYLVANIA HOSP.
3400 SPRUCE STREET. PHIIADEIPHIA. PA Lett ventricle lunclion in
aortic regurgitation (human)
-03 (MET) BRUNZfll, JOHN D, UNIVERSITY Of WASHINGTON. D£
PARTMENI 0( MfOlCINf, RG 20 . SEAHLE. WASH Palhophyiiology ol
genetic hypertriglyccrinemias (human)
-03 (CVB) 01 FERRANTi, NICOLA M, BAYLOR COLLEGE OF
MEDICINE. 1200 MOURSUND. HOUSTON. TEX Glycojaminoglycanj and
lipoproteins ol human plasma
■03 (MET) FIELDING, CHRISTOPHER J, UNIVERSITY OF CALIFORNIA.
CARDIOVASCUUR RES INST. SAN FRANCISCO. CALIF Regulation of
plasma triglyceride metabolism (rats)
.03 (HEP) CHANCE, BRITTON, UNIVERSITY Of PENNSYLVANIA.
SCHOOL OF MEDICINE. PHILADELPHIA. PA Oxygen, energy and conlrac
tility in cardiac tissue
-03 0003 (HEP) ERECINSKA, MARIA. Oxygen, energy and conUac
tihty in cardiac tissue Structural functional studies on cytochrome c
oxidase
03 0004 (HEP) BIASIE, J KENT. Oxygen, energy and contractility in
cardiac tissue Structural-functional studies on sarcoplasmic reticulum
(rabbits)
03 0005 (HEP) SCARPA, ANTONIO. Oxygen, energy and contrac-
tility in cardiac tissue-Cytosolic calcium homeostasis and bioener-
getics of cardiac tissue (animals)
03 0007 (HEP) HOLTZER, HOWARD. Oxygen, energy and contrac
tility in cardiac tissue -Surfaces, energy requirements, and contractile
proteins of cardiac cell in vitro.
03 0008 (HEP) HOLTZER, HOWARD. Oxygen, energy and contrac
tility in cardiac tissue -Cardiac cell culture facility
■03 0009 (HEP) WILLIAMSON, JOHN R. Oxygen, energy and con
tractility in cardiac tissue -Regulation of oxygen utilization of cardiac
tissue (rats, rabbits).
-03 0010 (HEP) CHANCE, BRITTON. Oxygen, energy and contractili-
ty in cardiac tissue-Tissue oxygen utilization (rats, dogs),
.02 (CVA) CHEUNG, PETER W, CASE WESTERN RESERVE UNIV, 501
WICKENDEN, CLEVELAND, OHIO. Noninvasive reflection oximetry in
peripheral tissue (dogs),
03 (CVA) SPEREIAKIS, NICK, UNIVERSITY OF VIRGINIA, JORDAN
HALL. CHARLOTTESVILLE. VA. Electrophysiology of heart cells (rats.
chicks).
.03 (NTN) GUTHRIE, HELEN A, PENNSYLVANIA STATE UNIV. ROOM
202B. UNIVERSITY PARK. PA. Iron deficiency-hyperlipidemia in develop-
ment (rats).
-04 (PTHA) TREISTAO, ROBERT I. MASSACHUSETTS GENERAL
HOSPITAL, 51 BLOSSOM STREET, BOSTON, MASS Cardiovascular
matrix-Morphogenesis and maturation (human, chick embryo, mam-
mal).
-02 (EDO APOSTOIIDES, ARISTIDE Y, UNIVERSITY OF MARYLAND.
31 SOUTH GREENE STREQ, BALTIMORE, MD, Hypertension incidence
project (human),
,04 (CVB) RAMWELl, PETER W, GEORGETOWN UNIVERSITY, 3900
RESERVOIR ROAD, N W, WASHINGTON, D C, Prostaglandin precursors
and vascular reactivity (dogs).
■03 (GEN) CORTNER, JEAN A, CHILDREN'S HOSPITAL. 34TH & CIVIC
CENTER BLVD. PHILADELPHIA, PA, Genetic heterogeneity of acid lipase-
■Atherosclerosis (human),
-03 (BBCB) CHEUNG, PETER W, CASE WESTERN RESERVE UNIV,
501 WICKENDEN BUILDING, CLEVEUND, OHIO, Light-scattering studies
of the sickling process (human).
-03 (CVB) GOMEZ-SANCHEZ, CEISO E, UNIVERSITY OF TEXAS,
5323 HARRY HINES BOULEVARD, DALLAS, TEX. Role of mineralocorti-
coids in low renin hypertension (human, rats).
-02 (SGYA) IIIIEHEI, RICHARD C, UNIVERSITY OF MINNESOTA,
MAYO MEMORIAL BLDG, BOX 490. MINNEAPOLIS. MINN. RES stimulat-
ing materials in experimental shock (dogs).
.03 (CVA) BRATZIER, ROBERT L, PRINCETON UNIVERSITY, DEPT OF
CHEMICAL ENGINEERING, PRINCETON. N J, Protein transport through
arterial tissue (rabbits).
■03 (BBCB) KRIMM, SAMUEL, UNIVERSITY OF MICHIGAN. 729
PHYSICS-ASTRONOMY BLDG, ANN ARBOR, MICH. Human erythrocyte
membrane structure.
-02 (SGYA) HARRIS, WIlllAM H, MASSACHUSETTS GENERAL
HOSPITAL. FRUIT STREET. BOSTON, MASS. Prevention of postoperative
venous thrombi (human, cattle).
-03 (BMT) LOBERG, MICHAEL D, UNIVERSITY OF MARYLAND. 22 S
GREENE STREET. BALTIMORE. MD. Preparation of radiopharmaceuti-
cals from drug analogs.
02 (BBCA) SAKURA, J DAVID, MC LEAN HOSPITAL. 115 MILL
STREET, BELMONT, MASS. Chemical studies on proteolipid apoproteins
(cattle).
1-03 (CVA) WEBER, KARL T, HOSP/UNIV OF PENNSYLVANIA. 3400
SPRUCE STREET, PHILADELPHIA, PA. Ventricular mechanics in the
overloaded heart (dogs).
03 (SGYA) HUMPHREY, EDWARD W, 54TH ST & 48TH AVE SO,
MINNEAPOLIS, MINN. Post-traumatic pulmonary insufficiency (dogs).
-03 (SGYA) SPARKS, ROBERT E, WASHINGTON UNIVERSITY, LINDELL
& SKINKER, ST LOUIS, MO. Biosorbable thromboresistant surfaces
(dogs, rats, swine, human).
'-04 (SRC) MYERBURG, ROBERT J, UNIVERSITY OF MIAMI. DEPART-
MENT OF MEDICINE, MIAMI, FLA. Studies in survivors of lethal arr-
hythmias (human).
.04 (SRC) HINKLE, LAWRENCE E, JR, CORNELL UNIVERSITY, 1300
YORK AVENUE, NEW YORK, N Y. Prevention of acute and fatal car-
diovascular disease (human).
1-04 (SRC) LOWN, BERNARD, HARVARD SCHOOL OF PUBLIC HLTH,
665 HUNTINGTON AVENUE, BOSTON, MASS. Detection and control of
ventricular premature beats (human).
.03 (SRC) BASHE, WINSIOW J, JR, COLLEGE OF MEDICINE. 400 W
lOTH AVENUE, COLUMBUS, OHIO. Clinical-pathologic studies of sudden
cardiac death (human).
18762
• 18764
PROJECT NUMBER AND INVESTIGATOR ADDRESS
560
I
I
R01HI-I8794
R01HL-18795
R01HL.
ROIHl-
18796
18798
R01HL-I8798
ROIHl-18798
R01HL-18798-
R01HL-I8800
R01HI.I880S
R01HL-I880S.
R01HI-I880S-
18805
18805
ROIHL
ROIHL
R01H1.18805
R01HL-18808
ROIHL-18808
ROIHL.
ROIHL
ROIHL-
ROIHl-
'18808
18814
18815
18818
ROIHl-18819
R01HL-18823
R01HL-18824
R01HL-18826
POIHl-18827
POIHt-18827
POIHL-18827
P01HL-18827-
P01HI-I8827
POIHL
POIHL-
18827
18827
P50HL-18828-
P50HL-
PSOHL-
P50HL-
18828
18828
18828.
P50HL-18828
PSOHl.18828
■°''cn!,Tu*^L«?^.T^ ''^NNETH M, UNIVERSITY Of ILLINOIS, 840
SOUTH WOOD STREET, CHICAGO, ILL. Prospective studies of conduc-
tion disease (human).
-04 (SRC) WATANABE, AUGUST M, INDIANA UNIVERSITY 1100
WEST MICHIGAN STREET, INDIANAPOLIS, IND Ischemic arrhythmias--Ef-
tect of autonomic tone (dogs, rats, guinea pigs)
■°*.wl-*.'''^' "*'^' ■'*°''' *'-^*NY MEDICAL COLLEGE, NEW SCOTUND
AVENUE. ALBANY, N Y. Experimental cardiac arrhythmias (dogs)
-04 (SRC) BROWN, ARTHUR M, UNIVERSITY OF TEXAS DEPT OF
PHYSIOL & BIOPHYSICS, GALVESTON, TEX. Nervous and ionic factors
in sudden cardiac death.
■04 0001 (SRC) KUNZE, DIANA I. Nervous and ionic factors in
sudden cardiac death-Potassium loss during myocardial ischemia
(rabbits).
■04 0002 (SRC) BROWN, ARTHUR M. Nervous and ionic factors in
sudden cardiac death-Electron microprobe, ultrastructure analysis of
ischemic myocardium (dog, rabbit).
■04 0003 (SRC) STONE, HUBERT L. Nervous and ionic factors in
sudden cardiac death-Left stellectomy in the prevention of sudden
death (dogs).
-04 (SRC) GOLDSTEIN, SIDNEY, HENRY FORD HOSPITAL 2799 WEST
GRAND BOULEVARD, DETROIT. MICH. Prospective study of resuscitated
sudden death victims (human).
-04 (SRC) DODGE, HAROLD T, UNIVERSITY OF WASHINGTON
SCHOOL OF MEDICINE RG-20. SEAHLE, WASH. Sudden cardiac deatti
and the onset of myocardial infarction.
■04 0001 (SRC) BRUCE, ROBERT A. Sudden cardiac death and the
onset of myocardial infarction-Predictive value of maximum exercise
stress testing (human).
04 0003 (SRC) DODGE, HAROLD T. Sudden cardiac death and
the onset of myocardial infarction-Prediction from clinical and labora-
tory assessments (human).
-04 0004 (SRC) COBB, LEONARD A. Sudden cardiac death and
the onset of myocardial infarction-Sudden death survivors-Clinical
follow-up and therapy (human).
-04 0005 (SRC) HAMILTON, GLEN W. Sudden cardiac death and
the onset of myocardial infarction -Sudden death survivors-
Radionuclide studies (human).
-04 0007 (SRC) REICHENBACH, DENNIS D. Sudden cardiac death
and the onset of myocardial infarction -Analysis of pathologic factors
involved in sudden death (human).
-04 (SRC) OLIVER, G CHARLES, BIOMEDICAL COMPUTER UB 700
SOUTH EUCLID AVENUE, ST LOUIS, MO Prediction and prevention of
sudden cardiac death.
■04 0001 (SRC) OLIVER, G CHARLES. Prediction and prevention of
sudden cardiac death -Prognostic significance of premature ventricu-
lar contractions (human).
1-04 0003 (SRC) OLIVER, G CHARLES. Prediction and prevention of
sudden cardiac death -Technical support (computer)
■03 (EXP) ABEL, GENE G, MEMPHIS MENTAL HEALTH INST 865
POPLAR AVENUE, MEMPHIS, TENN. Behavioral tactics for clinical car-
diac control (human).
■03 (SGYB) SILVER, DONALD, UNIVERSITY OF MISSOURI 807 STADI-
UM ROAD, COLUMBIA. MO. Surgical vascular disorders (human dogs)
1-04 (BBCB) YANG, JEN T, UNIVERSITY OF CALIFORNIA, 825-HSW
SAN FRANCISCO, CALIF. Stereochemical mechanism of sickling of
hemoglobin S (human).
-07 (BBCB) MANNING, JAMES M, ROCKEFELLER UNIVERSITY 1230
YORK AVENUE, NEW YORK, N Y. Chemical studies on sickle cell
hemoglobin (human).
•02 (EXP) ELDER, S THOMAS, UNIVERSITY OF NEW ORLEANS
LAKEFRONT, NEW ORLEANS, U. Physiological correlates of conditioned
blood pressure (human).
■03 (PTHA) SONNENBLICK, EDMUND H, ALBERT EINSTEIN COL
LEGE OF MED, 1300 MORRIS PARK AVENUE, BRONX, N Y. Mechanisms
of heart failure in myopathic hamster.
i-04 (PTHA) JOHNSON, ALICE R, UNIVERSITY OF TEXAS 5323
HARRY HINES BLVD, DALLAS. TEX. Interaction of peptides and' target
cells in lung (human).
-02 (HEPA) COIMAN, ROBERT W, UNIVERSITY OF PENNSYLVANIA
3400 SPRUCE STREET, PHIUDELPHIA, PA. Platelet vessel wall interac-
tions in thrombogenesis.
-02 0001 (HEPA) KEFALIDIES, NICHOLES A. Platelet vessel wall
interactions in thrombogenesis-Role of endothelial cells in the produc-
tion of thrombi (human, cattle).
■02 0002 (HEPA) JIMENEZ, SERGIO A. Platelet vessel wall in
teractions in thrombogenesis-lnteractions of vessel wall
macromolecules with factor XII (human, rats)
02 0003 (HEPA) GASIC, GABRIEL J. Platelet vessel wall interac-
tions in thrombogenesis-Tumor cell and platelets in thrombogenesis
and metastasis (human, animals).
-02 0005 (HEPA) COLMAN, ROBERT W. Platelet vessel wall in-
teractions in thrombogencsis-Platelet vessel wall interactions in
thrombogenesis (human)
•02 0006 (HEPA) SCHREIBER, ALAN D. Platelet vessel wall in-
teractions in thrombogenesis-Platclet immune injury in man
•02 0007 (HEPA) COLMAN, ROBERT W. Platelet vessel wall in
teractions in thrombogenesis-Biochemistry and role factor V in throm-
bogenesis (human, cattle).
•03 (SRC) NACHMAN, RALPH L, CORNELL UNIVERSITY, 1300 YORK
AVENUE, NEW YORK. N Y. Specialized center of research in thrombo-
sis.
■03 0001 (SRC) NACHMAN, RALPH L. Specialized center of
research in thrombosis-Membrane biology and hemostasis (human)
-03 0002 (SRC) JAFFE, ERIC A. Specialized center of research in
thrombosis-Endothelial cell biology (human, guinea pig)
-03 0003 (SRC) HARPEL, PETER C. Specialized center of research in
hrombosis-Structure and function of plasma coagulation inhibitors
(human).
■03 0004 (SRC) POLLEV, MARGARET J. Specialized center of
research in thrombosis -Membrane changes in platelet physiology-Role
of complement (mice, human).
■03 0005 (SRC) WEKSLER, BABETTE B. Specialized center of
research in thrombosi.-Platelet inflammatory factors in thrombosis
(human, guinea pig).
P50HI
P50HL
P50HL-
ROIHL-
R01HL
R01HL-
R01HL
ROIHL
R01HL-
R01HL-
R01HL-
ROIHL
ROIHL
ROIHL-
R01HL-
R01HL-
R01HL
ROIHL
ROIHL-
ROIHL-
R01HL-
R01HL-
ROIHL
R01HL-
ROIHL-
ROIHL-
ROIHL-
R01HL-
R01HL-
ROIHL-
R01HL-
R01HL-
ROIHl.
R01HL-
R01HL-
■18828-03 0006 (SRC) BECKER, CARL G. Specialized center of research in
thrombosis-Etiology and pathogenesis of atherosclerosis (rabbit mon-
key, rat, human).
18828-03 0008 (SRC) MARCUS, AARON J. Specialized center of
research in thrombosis-Biochemistry, physiology-Platelets and subcel-
lular platelet particles (human).
18828-03 0009 (SRC) RABELLINO, ENRIQUE. Specialized center of
research in thrombosis -Platelet formation and megakaryocyte cell
biology (guinea pig, human).
18831-03 (CVB) JOKELAINEN, PENTTI T, UNIVERSITY OF MICHIGAN 4643
MEDICAL SCIENCE II, ANN ARBOR, MICH. Microscopy of spontaneously
hypertensive arterial lesion (rats).
18834-04 (HEM) FURIE, BARBARA C, NEW ENGUND MED CENTER HOSP
171 HARRISON AVENUE. BOSTON. MASS. Metal-dependent complex for
mation in blood coagulation (human, cattle).
18845-04 (CVB) MC GIFF, JOHN C, UNIV OF TENN CTR FOR THE HLTH
800 MADISON AVENUE, MEMPHIS, TENN. Regulation of renal circula-
tion and salt excretion (rats. dogs).
•18848-03 (CVB) PATTERSON, DONALD F, UNIVERSITY OF PENNSYLVANIA
3800 SPRUCE STREET. PHIUDELPHIA, PA. Etiology and development of
congenital heart disease (dogs. cats).
■18850-03 (EDO PIPBERGER, HUBERT V, VETERANS ADMINISTRATION
HOSP, 50 IRVING STREET, N W, WASHINGTON, D C. Classification code
for Frank orthogonal EGG.
18852-03 (HEM) HANAHAN, DONALD J, UNIVERSITY OF TEXAS 7703
FLOYD CURL DRIVE. SAN ANTONIO. TEX. Biochemical studies on the
blood coagulation process (human, cattle).
18859-03 (HEM) SCHIFFMAN, SANDRA, UNIV OF SOUTHERN CALIFORNIA
2025 ZONAL AVENUE, LOS ANGELES, CALIF Biochemistry of human
factor XI (human).
18862-02 (CVB) RAMSAY, DAVID J, UNIVERSITY OF CALIFORNIA ROOM S-
762, SAN FRANCISCO, CALIF. Thirst and its contribution to edema
(dogs).
-18866-02 (CVA) BAKER, CARLETON H, UNIVERSITY OF SOUTH FLORIDA
BOX 8 12901 N 30TH STREET, TAMPA, FLA. Microvascular flow'
volume, and reactivity (rats. cats).
•18868-03 (PHY) OPDYKE, DAVID F, NEW JERSEY MEDICAL SCHOOL 100
BERGEN STREET. NEWARK. N J. Development of vertebrate vascular
control systems (reptiles, amphibians).
18873-02 (RAO) ZISKIN, MARVIN C, TEMPLE UNIVERSITY, 3400 NORTH
BROAD STREET, PHILADELPHIA. PA. Early radiologic diagnosis of car-
diac failure (monkey).
18875-03 (CVB) KUNAU, ROBERT T, JR, UNIVERSITY OF TEXAS 7703
FLOYD CURL DRIVE. SAN ANTONIO. TEX. Angiotension. prostaglandins
pressure and the kidney (rats).
18876-03 (GEN) DARLINGTON, GRETCHEN J, CORNELL UNIVERSITY
1300 YORK AVENUE, NEW YORK. N Y. Human alpha-1-antitrypsin'
synthesis in vitro.
-18878-03 (MET) KHACHADURIAN, AVEDIS K, RUTGERS MEDICAL
SCHOOL, POST OFFICE BOX, PISCATAWAY, N J Familial
hypercholesteremia-Studies of fibroblasts (human)
•18882-02 (CVB) WILLIAMS, GORDON H, PETER BENT BRIGHAM HOSP
721 HUNTINGTON AVENUE, BOSTON, MASS. Hormones in hypertension
(human).
■18887-03 (MET) MEISNER, HERMAN M, CASE WESTERN RESERVE UNIV
DEPARTMENT OF PHARMACOLOGY, CLEVEUND, OHIO. Hypolipidemic
drugs-Effects on FFA-albumin association (human cattle)
18891-02 (CVB) LANGFORD, HERBERT G, UNIVERSITY OF MISSISSIPPI,
2500 NORTH STATE STREET, JACKSON, MISS. Electrolyte Intake and
blood pressure in hypertension (human)
18893-03 (CVB) KNYCH, EDWARD T, JR, UNIVERSITY OF MINNESOTA
2205 E 5TH STREET, DULUTH. MINN. Mechanism of angiotensin ac-
tion-Role of receptor (rats).
18900-03 (PHY) WINEGRAD, SAUL, UNIVERSITY OF PENNSYLVANIA DE-
PARTMENT OF PHYSIOLOGY, PHIUDELPHIA, PA. Intercellular factors in
function of cardiac cells.
•18905-04 (BBCA) WONG, KIN-PING, UNIVERSITY OF KANSAS, RAINBOW
BLVD AT 39TH AVENUE. KANSAS CITY, KANS. Acquisition of native con-
formation of proteins (human, cattle)
■18907-03 (EDO DEBUSK, ROBERT F, 730 WELCH ROAD. PALO ALTO CALIF
Objective evaluation early after Ml and heart surgery (human)
18908-03 (PBC) WILSON, IRWIN B, UNIVERSITY OF COLORADO DEPART-
MENT OF CHEMISTRY. BOULDER. COLO. Angiotensin converting enzyme
of human serum.
18912-03 (CVB) SAGAWA, KIICHI, JOHNS HOPKINS UNIVERSITY 720 RUT-
UND AVENUE, BALTIMORE, MD. Mechanics of heart muscle contrac-
tion (cats, dogs).
"'"*'°lpN?';*r''M'!^o,TL"°"" "' UNIVERSITY OF CALIFORNIA, DEPART-
MENT OF NUTRITION, DAVIS, CALIF. Characterization of lung elastins
(rat, rabbit, chicken. Rhesus).
18923-02 (PTHA) GALLA, JOHN H, UNIVERSITY OF KENTUCKY DEPART-
MENT OF MEDICINE. LEXINGTON, KY. Steroid-induced hype'rllpfdem,>
and hypertension (human, rats).
■18931-02 (PBC) RICHMOND, VIRGINIA L, UNIVERSITY OF WASHINGTON
PHYSIOLOGICAL NURSING SM-24, SEAHLE, WASH. Lung elastic t' sue
characteristics (swine, human).
18932-03 (CVB) ROSENBLUM, WILLIAM I, MEDICAL COLLEGE OF VIR-
G NIA, BOX 17, MCV STATION, RICHMOND, VA. Brain microcirculation
observed in vivo after trauma (mice).
18933-03 (CVA) PIEPER, HEINZ P, OHIO STATE UNIVERSITY 333 WEST
lOTH AVENUE, COLUMBUS, OHIO. Energy output and efficiency of left
ventricle (dog).
18935-03 (HEM) CHAO, FRANCIS C, CENTER/BLOOD RESEARCH INC 800
HUNTINGTON AVENUE, BOSTON. MASS. Platelets, fibrinogen, solubl
tibrin interaction (human).
18936-02 (SGYA) MEMMI, CARLOS, HARBOR GENERAL HOSPITAL 1124
WEST CARSON STREET, TORRANCE, CALIF. Heart preservation and
transplantation studies (rat).
18937-03 (HEM) FEINSTEIN, MAURICE B, UNIVERSITY OF CONNECTICUT
263 FARMINGTON AVENUE, FARMINGTON, CONN. Cyclic nucleotides
and calcium in platelets (human).
18938-03 (PC) KUMAR, SURIENDER, NEW JERSEY MEDICAL SCHOOL 100
BERGEN STREET, NEWARK, N J. Pulmonary fatty acid and phospholipid
metabolism (rats).
561
B01MI.1M43.0S (fMY) TAim. CHARIIS M, UNIV Of KANSAS MEDICAL CfNIfR.
DEPARTMENT OF PHYSlOLOCy, KANSAS CITY. KANS ConKaclilo «clivity
ol single csidiac cells
tOIMl-1 8947-02 (AFY) OlODfS. ISSUE A, PURDUE UNIVERSITY. ROOM 32. EE
BUIIOING, WEST LAfAYEIlE. IND Indirect mean arterial pressure
l«0IHl.l894B.037sOYA) BEHNSTEIN. EUGENE f. UNIVERSITY HOSPITAL. 22S
WEST DICKINSON STREET, SAN DIEGO. CALIF Pulseless llow and citcu
latory assistance (doBs. calves)
RO,H1.1B9S2.03 (PTHA) RANKIN. JOHN H. UNIVERSITY Of WISCONSIN. 750
UNIVERSITY AVENUF, MADISON. WIS Metabolism in perfused fetal and
newborn labbit lungs
ROT HL.l 8968-03 (COM) HERMAN. OABOR T, S U N Y AT BUFFALO 4226
RIDGE LEA, AMHERST. N Y Computer technology lor transaxial tomog
«01Hl.18969.027cVA) CRAWFORD, DONAID W. UNIV OF SOUTHERN CALIFOR
NIA. 2025 ZONAL AVENUE, LOS ANGELES, CALIF Arterial wall oxygena-
tion (rabbits, dogs)
POIHl-l 8974-03 (HEPA) REIS, DONALD J, CORNELL UNIVERSITY. 130C YORK
AVENUE. NEW YORK, N Y Experimental neurogenic hypertension pro-
gram .
POlHl-1 8974-03 OOOT (HEPA) REIS, DONAID J. Experimental neurogenic hyper
tension program- Central neural systems regulating arterial pressure
(rabbits)
P01 HI- 18974-03 0006 (HEPA) NATHAN, MARC A. Experimental neurogenic
hypertension program -Model of sustained arterial hypertension (cats)
POlHl-l 8974-03 0008 (HEPA) REIS, DONALD J. Experimental neurogenic hyper
tension program -Monoamines and hypertension (rats)
POIHl-l 8974-03 0009 (HEPA) JOH, TONG H. Experimental neurogenic hyperten-
sion program Biochemistry of brain tyrosine hydroxylase (rats)
POIHL-1 8974-03 0010 (HEPA) JOH, TONG H. Experimental neurogenic hyperten-
sion program -Biochemistiv and regulation of PNMT in brain (rats).
POIHl-l 8974-03 0011 (HEPA) JOH, TONG H. Experimental neurogenic hyperten-
sion program-Biochemistry and regulation of brain tryptophane
hydroxylase (rats).
P01HL-18974-03 0012 (HEPA) PICKEl, VIRGINIA M. Experimental neurogenic
hypertension program -Immunohistochemistry of central monoamine
neurons (rats).
POlHL-l 8974-03 0014 (HEPA) REIS, DONAID J. Experimental neurogenic hyper
tension program -Administrative core.
P01HL.1 8974-03 001 S (HEPA) JOH, TONG H. Experimental neurogenic hyperten-
sion program-Neurochemistry core.
POIHl-l 8974-03 0016 (HEPA) REIS, DONAID J. Experimental neurogenic hyper
tension program -Neuroanatomy core
POlHl-1 8974-03 0017 (HEPA) NATHAN, MARC A. Experimental neurogenic
hypertension program -Computer-physiology core.
ROlHl-1 8976-03 (EXP) OBRIST, PAUl A, UNIVERSITY OF NORTH CAROLINA. DIVI-
SION OF HEALTH AFFAIRS. CHAPEL HILL. N C. Blood pressure control-
Relation to behavioral stress (human, dog).
ROIHl-l 8977-03 (CVA) FRONEK, ARNOST, UNIV OF CALIFORNIA, SAN DIEGO. LA
JOLU. CALIF, Non-invasive diagnosis of peripheral arterial disease
R01H1.18979.02\"cVA)''mORETTI, RICHARD I, CHILDREN'S HOSPITAL. 51ST AND
GROVE STREET. OAKLAND. CALIF Mechanisms in local regulation ot
coronary flow (rabbits).
R01HH8984-01 (AFY) MAZZARA, JAMES T, ST VINCENT'S HOSPITAL & MED CT
153 WEST IITH STREET. NEW YORK, N Y. P50 effect on exercise limit
in stable angina (human).
ROIHl-l 8993-03 (SSS) FOIKERS, KARl, UNIVERSITY OF TEXAS, INST FOR BIOMEDI-
CAL RESEARCH AUSTIN, TEX. Biological investigations of substance P.
ROIHl-l 8994-03 (SSS) PERNOW, BENGT 8, KAROLINSKA HOSPITAL, DEPT OF
CLINICAL PHYSIOLOGY, S-104 01 STOCKHOLM 60 SWEDEN. Substance
P-Occurrence, pharmacology and physiology (mammals non-human,
ROlHl-l 8995-04 "(SGYB) HARRISON, TIMOTHY S, MILTON S HERSHEY MEDICAL
CTR. 500 UNIVERSITY DRIVE, HERSHEY, PA. Cardiovascular determi-
nants of catecholamine release (dogs).
ROIHl-l 8997-02 (SGYA) WITTE, MARIYS H, ARIZONA MEDICAL CENTER, 1501 N
CAMPBELL AVENUE, TUCSON, ARIZ. Ischemic therapy in experimental
hypersplenism (rats, dogs).
ROlHl.19000-03 (PTHA) GANOTE, CHARIES E, NORTHWESTERN UNIV RSITY,
303 E CHICAGO AVENUE, CHICAGO, ILL. Irreversible myocardial iniury
R01Hl-19001-03"(PTHA) FUSTER, VALENTIN, MAYO FOUNDATION. 200 FIRST
STREET SOUTHWEST, ROCHESTER, MINN. Atherosclerosis in bleeder
and drug treated subjects (pigs).
ROIHl.19003-03 (RAD) PAULIN, SVEN J, BETH ISRAEL HOSPITAL, 330 BROOKLINE
AVENUE. BOSTON, MASS. High precision densitometry of coronarv an-
R01Hl-19008-02^'°(PHY) ENNS, THEODORE, UNIV OF CALIFORNIA. SAN DIEGO
MARINE BIOLOGY RES DIV A-002. U JOLLA. CALIF. Carbon dioxide dif-
fusion in lung and muscle tissues (dogs). „„„,„
ROIHl-19009-03 (CVB) PHILLIPS, STEVEN J, TEMPLE UNIVERSITY. 3400 N BROAD
STREET. PHILADELPHIA. PA. Morphometric analysis of the sinoatrial
R01Hl.l9010-03"°('cVArFROSOlONO, MICHAEl F, ALBERT EINSTEIN COLLEGE
OF MED. 1300 MORRIS PARK AVENUE. NEW YORK. N Y. Metabolism
and cell biology of lung surfactant system (rabbits, sheep).
R01H1.1901I-03 (PBC) ADAMANY, ANTHONY M, ALBERT EINSTEIN COLL OF
MED. 1300 MORRIS PARK AVENUE. BRONX. N Y. Smooth muscle cell
membrane glycoprotein biosynthesis (cattle),
ROIHl-19012.03 (CVB) BLOOMQUIST, EUNICE I, TURS UNIVERSITY. 136 HAR-
RISON AVENUE, BOSTON, MASS. Smooth muscle of resistance vessels
in hypertension (rats).
ROlHl-19018-03 (PTHA) SCHWARZ, MARVIN I, UNIVERSITY OF COLORADO,
4200 EAST NINTH AVENUE, DENVER, COLO. Etiologic factors in cryp-
togenic fibrosing alveolitis (human).
ROlHl.19019-03 (RAD) DROST, CORNEIIS J, CORNELL UNIVERSITY. NEW YORK
STATE VETERINARY COLL. ITHACA. N Y. Accurate transcutaneous Dop-
pler blood flow monitoring.
ROlHl-1 9027-03 (CVB) BHALIA, RAMESH C, UNIVERSITY OF IOWA. 1-550 BASIC
SCIENCES BLDG. IOWA CITY. IOWA. Calcium and cyclic AMP in causa-
tion of hypertension (tats).
PROJECT NUMBER AND INVESTIGATOR ADDRESS
ROl HI- 1 9030-03 (SOYA) WIlllAM, OAY A. JR, HEW YORK HOSPIIAl. 525 EAST
68IH SIRftl. NfW YORK. N Y Tissue protection during circuUloiY rn
terruption (dogs) ..„.„roriiv nr
■ OIHL 19038-02 (SOYB) WMiiliR, H BROWNEU, UNIVERSItY Of
""'"' MASSCHUSflllS, 55 LAKE AVfNUf NORTH. WORCfSIER, MA
Plethysmographic evaluation ot carotid blood llow (human, r.bbits,
,01H1.19039-03''°(CVB) SHOUKAS, ARTIN A, JOHNS HOPKINS UNIVERSITY, 720
RUTUND AVENUE, BALTIMORE, MO Circulation studies by one vs two
R01Hl.,9044-037;::AriAslETT, ARTHUR I, UNIVERSITY OF MIAMI. P 0 BX
520875 BISCAYNE ANNEX . MIAMI, FU Elfecl ol drugs on develop
R0,Hl-1904S-03"^:cVA,"sPEAirJOSEPH F. UNIVERSITY OF PENNSYLVANIA, 3800
SPRUCE STREET PHILADELPHIA. PA Electrophysrology of cardiac auto-
R0,Hl.l,048-03":cv;;)'ru;,*'pAUl S, UN. of TEXAS MED BRANCH. OEPT OF
PHYSIOLOGY & BIOPHY. GALVESTON. TEX Structure ol baroreceptors in
R0,Hl-190S3-03^Tp"HArK;p:^N. HARRY A, NEW JERSEY MEDICAL SCHOOLJOO
BERGEN STREET. NEWARK. N ) Vascular anatomy of the telen-
R01Hl-190SS-03tGYA? TdMUNDS, I HENRY, JR, .000 RAVJIN INSTITUTE.
3400 SPRUCE STREET. PHILADELPHIA. PA Platelet function during ex
tracorporeal perfusion (human, mammals)
ROl Hl-1 9056-03 (CVA) HAMOSH, MARGIT, GEORGETOWN U SCHC^OL OF MED^
3900 RESEVOIR RO. N W. WASHINGTON. D C Blood triglycerides and
lipoprotein lipase rn the lung (rats) „.„.„t..c.ut nc
ROl Hl-1 9057-03 (CVB) BECK, NAMA, UNIVERSITY OF TEXAS. DEPARTMENT OF
MEDICINE. SAN ANTONIO. TEX Catecholamines and cyclic AMP in car-
diovascular system (rats, dogs) ,,„,„cd^itv «i w
ROlHl-19062.03 (PHRA) FERTEl, RICHARD H, OHIO STATE UNIVERSITY. 333 W
lOTH AVENUE. COLUMBUS. OHIO Pharmacologic control ot mast cell
phosphodiesterase (human, rats) „, „..,r,^olul» nc
ROl Hl-1 9063-03 (MET) EDWARDS, PETER A, UNIVERSITY OF CALIFORNIA. DE^
"° PARTMENT OF MEDICINE. LOS ANGELES. CALIF Cholesterol and
lipoprotein metabolism (rat hepatocytcs). ..„,,„-,
ROl Hl-1 9065-02 (BBCB) PIACHY, WIlllAM Z, SAN FRANCISCO STATE UNVERSI-
TY, 1600 HOLLOWAY AVENUE. SAN FRANCISCO. CALIF Molecular ox-
veen in biological fluids.
ROlHl-19066-03 (MCHA) COlWEll, WIlllAM T, SRI INTERNATIONAL 33
RAVENSWOOD AVENUE. MENLO PARK. CALIF. Synthesis and evaluation
of prostaglandin metabolites (guinea pigs). „„.,.„-„.„^,,t nc
ROl Hl-l 9068-03 (MBY) CHAN. lEE-NIEN I, UNIVERSITY OF CONNECTICUT. DE-
PARTMENT OF PHYSIOLOGY, FARMINGTON, CONN Changes in mem-
brane properties during erythropoiesis (chick embrYo).
ROl Hl-1 9072-03 (PTHA) WEISSMANN, GERAID, NEW YORK UNIVERSITY. 550
FIRST AVENUE. NEW YORK. N Y 10016. Modification of tissue in|ury in
myocardial infarction (dogs, human).
ROlHl-19073.02 (EDO COMSTOCK. GEORGE W, TRAINING CTR FOR PUB HLTH
RES. BOX 2067. HAGERSTOWN. MD. Heart disease and drinking water
ROl Hl-1 9076-03 '(CVB) JENSEN, RICHARD A, SRI INTERNATIONAL. 333 RAVEN^
SWOOD AVCNUE. MENLO PARK. CALIF. Vagal control of heart rate-A
biophysical model (rabbits). ..,-„...,
ROl Hl-l 9077-01 (PTHA) SIIVERSTEIN, EMANUEl, SUNY DOWNSTATE MEDICAL
CENTER. 450 CLARKSON AVENUE. BROOKLYN. N Y. Biochemistry and
molecular biology of sarcoidosis (human, rabbits).
ROlHl-19082-01 (PHY) HERIIHY, JEREMIAH T, UNIVERSITY OF TE)(AS 7703
FLOYD CURL DRIVE. SAN ANTONIO. TEX. Hypoxia-induced relaxation of
vascular smooth muscle.
ROl Hl-l 9083-02 (MCHB) ClARK. lElAND C, JR, CHILDREN'S HOSPITAL RES
"" FDN. ELLAND AND BETHESDA AVENUES. CINCINNATI. OHIO. Rapid
specific micro measurement of blood cholesterol.
ROlHl-19084-03 (MET) AlAOJEM, FREDERICK, UNIV OF SOUTHERN CALIFORNIA
2025 ZONAL AVENUE. LOS ANGELES, CALIF. Structure and function of
serum lipoproteins (human). ..„„„..,,,
ROlHl-19089-03 (CVA) GROSSMAN, WIlllAM, PETER BENT BRIGHAM HOSPITAL.
721 HUNTINGTON AVENUE. BOSTON. MASS. Diastolic properties of the
left ventricle (human, dogs).
R01HI-19091-02 (CVB) OETWEIIER, DAVID K, UNIVERSITY OF PENNSYLVANIA.
3800 SPRUCE STREET. PHILADELPHIA, PA. Sustained incre-se in car-
R01HI-19095-03'(BBCb7mARGOIIS, SIMEON, JOHNS HOPKINS UNIVERSITY, 725
NORTH WOLFE STREET, BALTIMORE, MD. Laser spectroscopy of
lipoproteins (human).
R01HI-1910S-02 (HEM) KISKER, C THOMAS, UNIVERSITY OF IOWA HOSPS, ROOM
247A MEDICAL LABS BLDG, IOWA CITY, IOWA. Detection and adherence
of fibrin monomer complexes (human).
ROl Hl-l 91 09-03 (PTHA) MINICK, CHARIES R, CORNELL UNIVERSITY, 1300 YORK
AVENUE, NEW YORK, N Y Regression of chronic atherosclerosis
R01Hl-19112-03"(CVB) PICK, RUTH, MICHAEL REESE HOSP & MED CTR, 29TH
STREET & ELLIS AVENUE, CHICAGO, ILL. Atherosclerosis studies
R01Hl-19115-02Ts"ssfRINARD, GILBERT A, EMORY UNIVERSITY. ATLANTA. GA.
Hormonal control of tracheobronchial cyclic AMP (rats, guinea pigs).
ROl Hl-l 91 18-03 (AFY) PIMMEl, RUSSEll I, UNIVERSITY OF NORTH CAROLINA.
MEDICINE DEPARTMENT. CHAPEL HILL. N C. Measurement of airways
mechanics (human, dog). ^„„..„,
ROlHl-19127.03 (SSS) REBA, RICHARD C, GEORGE WASHINGTON UNIVERSITY.
901 23RD STREET. N W, WASHINGTON. D C. Synthesis of molecules tor
myocardial imaging (rats).
ROl Hl-l 9 129-04 (PHRA) ASKARI, AMIR, MEDICAL COLLEGE OF OHIO. DEPT OF
PHARMA & THERAPEUTICS . TOLEDO, OHIO. Cardiac glycosides-
Mechanisms of cellular actions. „...„,„ ,.,
ROlHl.19131-04 (HEM) ROSENBERG, ROBERT D, SIDNEY FARBER CANCER IN-
STITUTE. 35 BINNEY STREET, BOSTON, MASS. Hypercoagulability and
assays for its protection (human).
ROlHl-191 32-04 (CTY) PHIlllPS, JERRY I, UNIVERSITY OF TEXAS, DIV/ALLIED
HLTH & LIFE SCIS, SAN ANTONIO, TEX. Role of zinc transferrin in
lymphocyte transformation (human).
ROlHl-191 33-03 (CVB) MC lAUGHlIN, ROBERT J, BOSTON UNIVERSITY, 80
EAST CONCORD STREET. BOSTON, MASS. Contractile and elastic pro-
perties of cardiac muscle (cats).
PROJECT NUMBER AND INVESTIGATOR ADDRESS
ROlHl-l 91 34-04 (CVB) MAIIK, KAFAIT U, UNIVERSITY OF TENNESSEE 800
MADISON AVENUE, MEMPHIS, TENN. Angiotensin, pros gland ns a' «
nergic interactrons (rats, rabbits)
ROlHl.19135-04 (CVA) BASSINGTHWAIGHTE. JAMES B. UNIVERSITY OF
WASHINGTON BIOENGINEERING CENTER, SEAHLE, WASH. He e ogene
ty of regional myocardial blood flow (dogs)
ROIHl-19136.03 (HED) MARKWALD. ROGER R TEXAS TEPH <;rHnni nc
MEDICINE, TEXAS TECH UNIVER^H, LUBBOCK EX Mu
■oiH. ,o,« ™''°'!'^f ^"^'i"* metabolism in cardiac anomalies (rats).
R0IHH9I38.03 (PHY) FABIATO, ALEXANDRE. MEDICAL COLLEGE OF VIRGINIA
skinned cardiac cells (mammals)
ROIHl-1 91 39-03 (CVB) BASSINGTHWAIGHTE, JAMES B UNIVERSITY OF
WASHINGTON, CTR FOR BIOENGINEERING RF.52 SeXhlE WASH
ROIHt 19,-^ „, ?^w=r °' "'""''"" '""'"""^ '" '"' """y <'^'""3". "Is, dogs)
R0IHI-J9I44.03 (CVB) BUNAG, RUBEN D, UNIVERSITY OF KANSAS 39TH ST AT
AINBOW BLVD. KANSAS CITY, KANS. Contraceptive steroids and eJ
perimental hypertension (rats)
ROIHl-19,48-03 (CBY) WEGUCKI, WIUIAM B. VIRGINIA COMMONWEALTH UNIV
1200 EAST BROAD STREET. RICHMOND, VA. Myocardial organelle hpid
structure and function (dog rat)
PS0HH9153-02 (HLBA) BRIGHAM, KENNETH I, VANDERBILT UNIVERSITY B
1 . MEDICAL CENTER, NASHVILLE. TENN. SCOR-Pulmonlry ed mas -
titology, pathogenesis.
PS0HL-,91S3.02 0001 (HIBA) BRIGHAM, KENNETH L. SCOR-Pulmonary
edemas-Eitology, pathogenesis-Prostaglandins and the lung circula
tion (sheep).
PSOHl-,9153.02 0002 (HIBA) BRIGHAM, KENNETH I. SCOR-Pulmonary
edemas^-Eitology pathogenesis-Lung fluid dynamics-Classical media-
tors and their inhibitors (sheep)
P50Hl-,9153.02 0003 (HIBA) BRIGHAM, KENNETH L SCOR-Pulmonary
edemas-Eitology, pathogenesis-Possible inhibitors of mediator release
and pulmonary vascular response (sheep)
P50Hl-,91 53-02 0004 (HLBA) HARRIS. THOMAS R. SCOR-Pulmonary edemas-
Eitology pathogenesis-Physical mechanisms in lung transvascular
transport-Math models (sheep)
P50HL-I91 53-02 0005 (HLBA) HARRIS. THOMAS R. SCOR-Pulmonary edemas-
Eitology pathogenesis-Lung vascular permeability measured by in-
dicator dilution methods (sheep)
P50HI-I9153-02 0006 (HLBA) SNEll, JAMES 0. SCOR-Pulmonary edemas-
tPtology, pathogenesis-Pulmonary vascular abnormalities in human
lung diseases.
P50HI-19153-02 0007 (HLBA) OWEN, PATTY J. SCOR-Pulmona-y edemas-Eitolo-
gy. pathogenesis-Core- Experimental laboratories and support facili-
ties.
P50HI-1 91 53-02 0008 (HLBA) HARRIS, THOMAS R. SCOR-Pulmonary edemas-
titology. pathogenesis -Core-Biomedical engineering
PS0HL-I9IS5-02 (SRC) STAUB, NORMAN C, UNIVERSITY OF CALIFORNIA CAR-
OIOVASCUUR RES INST, 1315M, SAN FRANCISCO, CALIF
Pathophysiology of pulmonary edema
P50HL-19,55.02 000. (SRC) MURRAY. JOHN F. Pathophysiology of pulmonary
edema-Pulmonary edema study unit (human, dog)
P50HL-19I5S-02 0002 (SRC) GORIN, ARNOLD B. Pathophysiology of pulmonary
edema-Non-invasive measurement of protein turnover in human lung
(also sheep). ^
P50HL-19,SS-02 0004 (SRC) STAUB, NORMAN C. Pathophysiology of pulmonary
edema-Physical and chemical effects of multiple pulmonary emboli
(sheep).
PS0HL-19]55-02 0005 (SRC) STAUB, NORMAN C. Pathophysiology of pulmonary
edema-Protein exchange sites and lymph protein concentration in
lung (mice, sheep).
PS0HI-J9IS5-02 0008 (SRC) MCDONALD, DONALD M. Pathophysiology of pul-
monary edema-Core microscopy laboratory
PSOHL.19156-02 (SRC) NADEL, JAY A, UNIVERSITY OF CALIFORNIA, CARDIOVASCU-
LAR RESEARCH INST, SAN FRANCISCO, CALIF. Pulmonary SCOR-
Lhronic diseases of airways
PSOHL-19156.02 0001 (SRC) NADEL, JAY A. Pulmonary SCOR-Chronic diseases
of airways-lrritability of airoays induced by epithelial damage in
healthy subjects (human).
P50HI-19I 56-02 0002 (SRC) GOLD, WARREN M. Pulmonary SCOR-Chronic dis-
eases of airways-Early detection of emphysema and chronic airway
obstruction (human, dog)
P50H1.1 91 56-02 0003 (SRC) NADEL, JAY A. Pulmonary SCOR-Chronic diseases
of airways-Powdered tantalum to study airway morphology and mu-
cociliary clearance (human).
PSOHl-l 91 56-02 0004 (SRC) GOLD, WARREN M. Pulmonary SCOR-Chronic dis
eases of airways-Interactions between mast cells, mediators and
nerves in canine asthma.
PSOHl-l 91 56-02 0005 (SRC) SAMPSON. SANFORD R. Pulmonary SCOR-Chronic
diseases of airways-Vagal receptors in the airway-Epithelial injury
and antigen (dog. cat, rabbit)
P50H1.19156-02 0006 (SRC) MCDONALD, DONALD M. Pulmonary SCOR-
Chronic diseases of airways-Core microscopy laboratory
PSOHL-1 91 57-02 (SRC) TALAMO, RICHARD C, JOHNS HOPKINS HOSPITAL DE-
PARTMENT OF PEDIATRICS, BALTIMORE, MO. Studies in cystic fibrosis
and bronchiolitis.
P50HI-191S7-02 0001 (SRC) BRUSILOW, SAUL W. Studies in cystic fibrosis and
bronchiolitis -Laboratory core unit
P50HL-191S7-02 0002 (SRC) ROSENSTEIN, BERYL J. Studies in cystic fibrosis
and bronchiolitis-Clinical core
P50HL-19I 57-02 0003 (SRC) PROCTOR, DONALD F. Studies in cystic fibrosis
and bronchiolitis -Nasal mucosal function in patients with cystic fibro-
sis.
P50Hl.I91S7.02 0004 (SRC) BANG, FREDERIK B. Studies in cystic fibrosis and
bronchiohtis-Macromolecular regulators of mucus secretion-Inver-
tebrate model.
P50HL-19157.02 0007 (SRC) TALAMO, RICHARD C. Studies in cystic fibrosis
Dcnu. ,„. bronchiolitis-Analysis of cystic fibrosis factors (human)
P50HL-19157.02 0008 (SRC) TAUMO, RICHARD C. Studies in cystic fibrosis
..»^. bronchiolitis -Serum proteins in cystic fibrosis (human)
P50HH9IS7.02 0009 (SRC) BAYLIN, STEPHEN B. Studies in cystic fibrosis and
p<«u. .o.., ^„'"°"'^'"<''"is-Polyamine metabolism in cystic fibrosis (human, rat).
P50Hl.I9157.02 0011 (SRC) HUGHES, WALTER. Studies m cystic fibrosis and
bronchiolitis -Pathogenesis of bronchiolitis (children).
562
PSOHL-l
P50HI
PSOHL
R01HL
ROIHl-
ROIHL-
PSOHl
PSOHL-
PSOHL-
P50HL-
PSOHL-
PSOHL
PSOHL-
PSOHl
PSOHL
P50HL-
PSOHL-
P50HL-
P50HL
PSOHL
P50HL-
P50HL-
P50HL.
PSOHL
P50HL-
P50HL
P50HL.
P50HL-
ROIHL
ROIHL
ROIHL-
ROIHL
P50HL-
P50HL-
P50HL
P50HL
19160-02 (SRC) BARBERO, GIULIO J, UNIVERSITY OF MISSOURI, DEPART-
"brosis ""^™' '^''^™^'*- "^ """" ^""O™^!''/ in cystic
19160-02 0001 (SRC) MARTINEZ, J RICARDO. Mucus abnormality in
io,«.n „ "^"''c '''"■"S's-ReBulation of respiratory secretions (rat, human)
-19160-02 0002 SRC) SPICER, SAMUEL S. Mucus abnormality in cystic
f^brosis-Ultrastructure. cytochemistry of pulmonary secretion (human,
-19163-02 (EVR) SHERBURNE, STUART W, FISHERIES RESEARCH STATION
OEPT OF MARINE RESOURCES. WEST BOOTHBAY HARBOR, MAINE
Piscine erythrocytic necrosis in the Atlantic cod
-19164-03 (EVR) NICHOLSON, BRUCE L, UNIVERSITY OF MAINE DEPT OF
MICROBIOLOGY, ORONO, MAINE. Piscine erythrocytic necrosis' in the At-
■aniic cod.
•19168-03 (MET) MARSH, JULIAN B, MEDICAL COLL OF PENNSYLVANIA
300 HENRY AVENUE, PHILADELPHIA, PA. Biosynthesis of plasma
lipoprotein (rats, rabbits).
19170-02 (SRC) BRAIN, JOSEPH D. HARVARD UNIVERSITY, 665 HUNTING-
TON AVENUE, BOSTON, MASS. Harvard pulmonary SCOR-Chronic dis-
eases of the airways.
-19170-02 0001 (SRC) BRAIN. JOSEPH D. Harvard pulmonary SCOR-
Chronic diseases of the airways -Natural history, reversibility of pulmo-
nary abnormalities in smokers (human)
.19170-02 0003 (SRC) INGRAM. ROLAND H. JR. Harvard pulmonary
SCOR-Chronic diseases of the airways -Mechanisms of bronchial reac-
tivity to acute and chronic airway challenge (dog)
■19170-02 0004 (SRC) BRAIN, JOSEPH D. Harvard pulmonary SCOR-
Chronic diseases of the airways-Exercise, increased ventilation effect
on airway exposure and responses (rodent)
19170-02 0005 (SRC) JAEGER, RUDOLPH J. Harvard pulmonary SCOR-
Chronic diseases of the airways-Pulmonary toxicology of plastics in-
termediates and pyrolysis products (animal)
19170-02 0006 (SRC) HOPPIN. FREDERIC G. Harvard pulmonary SCOR-
Chronic diseases of the ain«ays-Mechanism of overdistension
(human, animal).
""°-°l°°°: '"""i *»«=^A'"'EN. EDWARD R. Harvard pulmonary
SCOR-Chronic diseases of the airways -Therapy effect on airway ob-
struction in acute asthma (human)
•19170-02 0008 (SRC) LEITH. DAVID E. Harvard pulmonary SCOR-Chronic
diseases of the aiiways-Multiple-transient artificial coughing (dogs
human). '
•19170.02 0009 (SRC) LEITH, DAVID E. Harvard pulmonary SCOR-Chronic
diseases of the airways-Ventilatory muscle training in chronic ob-
structive pulmonary disease (human)
19170.02 0010 (SRC) DAWSON, STANLEY V. Harvard pulmonary SCOR-
Chronic diseases of the airways-Computer Core
""'"°l.i^"*^' ^'■^°^- WALLACE A, JR, UNIVERSITY OF NORTH
CAROLINA, DEPARTMENT OF PEDIATRICS, CHAPEL HILL, N C Pulmona
ry SCOR-Lung injury by childhood infections
-19171-02 0001 (SRC) COLLIER, ALBERT M. Pulmonary SCOR-Lung injury
by childhood infections-Longitudinal study-Respiratory infections and
lung growth in normal children
•19171-02 0003 (SRC) FERNALD, GERALD W. Pulmonary SCOR -Lung inju-
<y by childhood infections-Natural history, host defense defects-Chil-
dren with chronic pulmonary disease
.19171-02 0004 (SRC) DENNY, FLOYD W. Pulmonaiy SCOR-Lung injuiy by
childhood infections -Long-term effects of respiratory infections in
early childhood.
19171-02 0005 (SRC) LODA, FRANK A. Pulmonary SCOR-Lung injuiy by
childhood infections -Chronic respiratory disease of children in North
Carolina.
19171-02 0006 (SRC) CLYDE, WALLACE A, JR. Pulmonary SCOR-Lung
injury by childhood infections-Development of model systems
(bacteria, viruses, hamsters)
19171-02 0007 (SRC) FERNALD, GERALD W. Pulmonary SCOR-Lung inju-
ry by childhood infections-lmmunologic studies in models of lower
respiratory tract infection (rodents)
19171.02 0008 (SRC) COLLIER, ALBERT M. Pulmonary SCOR-Lung irrjury
by childhood infections-Host-parasite interaction-Electron microscopy
radioautography, histochemistry
19171-02 0009 (SRC) MUSE, KENNETH E. Pulmonary SCOR-Lung injury
by childhood infections-Host-parasite interaction-Scanning electron
microscopy, freeze-fracture methods
19171-02 0010 (SRC) BASEMAN, JOEL B. Pulmonary SCOR-Lung injury
by childhood infections-Metabolic pathways of normal and injured
respiratory cells.
19171-02 0011 (SRC) FERNALD. GERALD W. Pulmonary SCOR-Lung Inju-
ry by childhood infections-Clinical support core
'"''"°^°M;^'^"f' °^'*'*''- ''°^'' *■ '""""""'■> SCOR-Lung injury by
childhood infections-Laboratory support core
■19173-03 (SGY8) EBERHART, ROBERT C. UNIVERSITY OF TEXAS EN
GINEERING SCIENCE BLDG 608, AUSTIN, TEX. Analysis of blood trauma
from microporous oxygenators (human, dogs rabbits)
19175-03 (MET) MERIMEE. THOMAS J, UNIVERSITY OF FLORIDA BOX NO
239, GAINESVILLE, FLA. Pituitary modulation of micro-and macn.
vascular disease (human, rats).
19181-02 (BIO) KEELY, STANLEY L, JR, VANDERBILT UNIVERSITY DEPART-
MENT OF PHYSIOLOGY, NASHVILLE. TENN. Regulation of heart cAMP-
dependent protein kinase (rodents).
■19182-03 (SGVA) GEHA, ALEXANDER S, YALE UNIVERSITY. 333 CEDAR
STREET NEW HAVEN, CONN. Surgical aspects of myocardial hyper-
trophy (dogs).
19185-02 (HLBA) CLEMENTS. JOHN A, UNIVERSITY OF CALIFORNIA CAR-
DIOVASCUUR RES INSTITUTE, SAN FRANCISCO, CALIF Pulmona^
bCUH-Neonatal respiratory distress syndromes
19185-02 0001 (HLBA) WILLIAMS, MARY C. Pulmonary SCOR-Neonatal
respiratory distress syndromes-Sites of synthesis, secretion and struc-
ture of surface active material (rat)
■19185-02 0002 (HLBA) BENSON, BRADLEY J. Pulmonary SCOR-Neonatal
respiratory distress syndromes-Biochemistry, ultrastructure-Pulmonary
surface active material (human, animal)
19185-02 0003 (HLBA) KITTERMAN, JOSEPH A. Pulmonaiy SCOR-
Neonatal respiratory distress syndromes-Factors affecting formation
and release of pulmonaiy surfactant in fetal lambs.
S63
PROJECT NUMBER AND INVESTIGATOR ADDRESS
PS0Hl-l9lts-02 0004 (HIIA) BLAND, mCHARD D. Pulmonary SCOR'NMndsl
itspiotoiY dutress syndiomes Fluid and protein transport in total
and newborn lung (sheep, rabbits)
P$0Hl-l9185-02 OOOS (HIBA) BAllARD, PHIIIP I. Pulmonary SCOR Neonatal
respiratory distress syndromes Role and mechanism ol (lucocorticoids
in fetal lung maturation (human, rabbit)
P50HI-19I85-07 0006 (HIBA) PHIBBS, RODERIC H. Pulmonary SCOR Neonatal
respiratory distress syndromes Evaluation ol risk factors in neonatal
respiratory distress (human, sheep)
PS0HI-1918S-02 0007 (HIBA) BIAND, RICHARD D. Pulmonary SCOR Neonatal
respiratory distress syndromes Sodium bicarbonate and albumin in
resuscitation of preterm infants (human)
PSOHL-19) 85-02 0009 (HIBA) BRADY, JUNE P. Pulmonary SCOR Neonatal
respiratory distress syndromes Nasal continuous positive airway pros
sure in hyaline membrane disease (human)
PS0HL-I9I85-02 0011 (HIBA) TOOLEY, WIIUAM H. Pulmonary SCOR Neonatal
respiratory distress syndromes Complications and sequelae of
neonatal respiratory distress (human)
PSOHI-I9I8S-03 0012 (HLBA) MCDONALD, DONALD M. Pulmonary SCOR
Neonatal respiratory distress syndromes Core microscopy lab
P50HL-1 91 87-02 (SRC) HODSON, WILLIAM A, UNIVERSITY OF WASHINGTON.
SCHOOL OF MEDICINE. SEAHLE. WASH Pediatric pulmonary SCOR ■
Hyaline membrane disease
PSOHl-19187-02 0001 (SRC) HODSON, WILLIAM A. Pediatric pulmonary SCOR
Hyaline membrane disease Hyaline membrane disease -Changes in
lung mechanics and gas exchange (monkeys)
P50HL-19187-02 0002 (SRC) PRUEITT, JOHN I. Pediatric pulmonary SCOR
Hyaline membrane disease Hyaline membrane disease-Alterations in
surface active material (monkeys)
P50HL-I9I87-02 0003 (SRC) lUCHTEl, DANIEL I. Pediatric pulmonary SCOR-
Hyaline membrane disease-Hyaline membrane disease -Ultrastructure
studies (monkey).
PSOHL-19187-02 0004 (SRC) PRUEITT, JOHN I. Pediatric pulmonary SCOR-
Hyaline membrane disease -Hyaline membrane disease -Surface active
material, lamellar bodies (mice, rats)
P50Hl-19t87-02 0007 (SRC) SELLS, CLIFFORD J. Pediatric pulmonary SCOR-
Hyaline membrane disease-Follow-up study-Infants with hyaline mem-
brane disease (human).
PS0HL-19)87-02 0009 (SRC) ZICK, GREGORY L. Pediatric pulmonary SCOR-
Hyaline membrane disease -Non-invasive measurement and monitoring
of arterial oxygen tension (dogs, sheep)
P50HI-19187-02 0010 (SRC) GUTHRIE, ROBERT D. Pediatric pulmonary SCOR-
Hyaline membrane disease -Treatment, outcome of HMD-Continuous
positive airway pressure (human, monkey)
P50HI-19187-02 0011 (SRC) KNAUSS, THOMAS A. Pediatric pulmonary SCOR -
Hyaline membrane disease-Effects of hypoxia and hypercapnia on
developing nervous system (monkey, human).
P50HL-I91 87-02 0012 (SRC) MEIER, ROBERT C. Pediatric pulmonary SCOR-
Hyaline membrane disease -Resource requirements, economic con-
sequence of HMD and recurrent apnea.
P50HL-191 87-02 0013 (SRC) STANDAERT, THOMAS A. Pediatric pulmonary
SCOR-Hyaline membrane disease -Research resources core.
P50HI-1 9 190-02 (SRC) NELSON, NICHOLAS M, MILTON S HERSHEY MEDICAL
CTR. 500 UNIVERSITY DRIVE. HERSHEY. PA. Pulmonary SCOR--
Pathophysiology. management of IRDS.
PSOHL-1 9 190-02 0001 (SRC) MAISELS, M JEFFREY. Pulmonary SCOR-
Pathophysiology. management of IRDS -Core -Clinical research center
(infants).
P50HL-19190-02 0002 (SRC) MAISELS, M JEFFREY. Pulmonary SCOR
Pathophysiology, management of IRDS -Core -Demonstration and dis-
semination.
PSOHL-19190-02 0003 (SRC) LADDA, ROGER L. Pulmonary SCOR -Pathophysiolo-
gy, management of IRDS-Type II cells-Regulation and differentiation
(rat).
P50HL-19190-02 0004 (SRC) RANNELS, D EUGENE. Pulmonary SCOR-
Pathophysiology. management of IRDS-Type II cells -Control of protein
turnover (rabbit).
P50HI-19190-02 0005 (SRC) DAVIDSON, EUGENE A. Pulmonary SCOR-
Pathophysiology. management of IRDS-Glycoproteins in mucous secre-
tions (human, cattle).
PSOHL-19190-02 0006 (SRC) BRENNAN, ROBERT W. Pulmonary SCOR-
Pathophysiology. management of IRDS-Asphyxia -Respiratory control
(dogs).
P50HL-1 9 190-02 0007 (SRC) VANNUCCI, ROBERT C. Pulmonary SCOR-
Pathophysiology. management of IRDS -Asphyxia-Cerebral metabolism
(dog. rat).
PSOHL-19190-02 0008 (SRC) NELSON, NICHOLAS M. Pulmonary SCOR-
Pathophysiology. management of IRDS-Hemodynamics and gas
exchange-Determinants of hypotension (human, infant).
P50HL-1 91 90-02 0009 (SRC) ULTMAN, JAMES S. Pulmonary SCOR-
Pathophysiology, management of IRDS-Developing non-invasive
neonatal pulmonary monitoring systems (rabbit, human).
ROIHL-1 91 95-03 (END) MORISHIGE, WALTER K, UNIVERSITY OF HAWAII AT
MANOA, DEPARTMENT OF PHYSIOLOGY, HONOLULU. HAWAII. Hormonal
regulation of lung function (rats).
ROIHL-1 9202-03 (CVA) MUSTAFA, SYED J, UNIVERSITY OF SOUTH ALABAMA. 307
UNIVERSITY BLVD. MOBILE. ALA. Adenosine, prostaglandins in relation
to coronary flow (guinea pigs).
R01HL-19203-03 (SGYA) DILLARD, DAVID H, UNIVERSITY OF WASHINGTON, DEPT
OF SURGERY, SEAHLE, WASH. Surgical approach to congenital heart
diseases (dogs, primates).
R01HL-19204-03 (AFY) FORSYTH, RALPH P, UNIVERSITY OF CALIFORNIA, 1315-
MOFFin HOSPITAL. SAN FRANCISCO.CALIF. Environmental factors in
hypertension (Rhesus monkeys).
ROIHl-1 9209-03 (CVB) SHARE, LEONARD, UNIVERSITY OF TENNESSEE. 894
UNION AVENUE, MEMPHIS, TENN. Role of ADH in experimental renal
hypertension (dogs, rats).
R01HL-19216-03 (CVA) STRAUSS, HAROLD C, DUKE UNIVERSITY. BOX 3845,
DURHAM, N C. Characterization of cardiac pacemaker activity (cat.
dog, rabbit).
R01HL-19218-03 (CVA) MORETTI, RICHARD L, CHILDREN S HOSPITAL. 51ST &
GROVE STREETS, OAKUND, CALIF. Local regulation of coronary flow by
prostaglandins (rabbits).
ROIHl.19223-03 (MET) RODWfll, VICTOR W, PURDUE UNIVERSIfY. DfPARI
MfNI ()( BIOCHtMISIRY. WtSI UfAYfllf. INO Control ol
choleslerogenesis in leukocytes and liver (rats, human)
ROIHI-I922S-02 (CVA) REID. LYNNi M, CHILDREN S HOSPIIAI MED CIR. 300
lONGWOOD AVFNUf. BOSION. MASS lypes and mechanimj o( pulmo
nary hypertension
ROIHl-19225-02 0001 (CVA) REID, LYNNE M. Types and mechanims of putmo
nary hypertension Structural changes (human, animals)
ROIHL-19225-02 0002 (CVA) REID, LYNNE M. Types and mechanims of pulmo
nary hypertension Effect of aorlo pulmonary shunt (pigs)
ROIHl-19225-02 0003 (CVA) REID, lYNNE M. Types and mechanims of pulmo
nary hypertension Cardiopulmonary function in pigs and rats
R01HL-1922S-02 0004 (CVA) REID, LYNNE M. Types and mechanims of pulmo
nary hypertension Structural changes in human pulmonary circulation
(human, animals)
ROIHL-19226-03 (CVB) HANSEN, TIMOTHY R, UNIVERSITY OF HEALTH SCIENCES.
2020 WEST OGDEN AVENUE. CHICAGO. ILL Vascular smooth muscle in
hypertension (rats)
ROIHl-19229-02 (CVB) MULROW, PATRICK J, MEDICAL COLLEGE OF OHIO. C S
100C8. TOLEDO. OHIO Prostaglandins and hypertension (human, rats,
dogs, rabbits)
R01HL-19232-03 (RAD) FORTUIN, NICHOLAS J, JOHNS HOPKINS HOSPITAL. 601
NORTH BROADWAY, BALTIMORE, MD ECHO changes in wall motion
with myocardial ischemia
ROIHL-1 9234-03 (BM) FREIMER, EARL H, MEDICAL COLLEGE OF OHIO. CALLER
SERVICE 10008. TOLEDO, OHIO. Streptococci and heart -Cellmedrated
cross-reaction (mice)
R01HL-19237-03 (PTHA) GEE, J BERNARD, YALE UNIVERSITY. 333 CEDAR
STREET. NEW HAVEN. CONN Obstructive lung disease and alveolar
macrophages (human, animals)
P01HL-19242-02 (HEPA) BERNE, ROBERT M, UNIVERSITY OF VIRGINIA. DEPT OF
PHYSIOLOGY, CHARLOTTESVILLE. VA. Study of vascular smooth muscle.
P01HL-19242-02 0001 (HEPA) ODESSEY, RICHARD. Study of vascular smooth
muscle -Energy metabolism and protein turnover in vascular smooth
muscle (rats)
P01HL-1 9242-02 0002 (HEPA) HOllOWAY, PETER W. Study of vascular smooth
muscle -Vascular smooth muscle response to serum lipoproteins
(rats).
PO I HL-1 9242-02 0003 (HEPA) RUBIO, RAFAEL. Study of vascular smooth
muscle-Vasoactive metabolites from vascular muscle and
parenchymal tissue (animal).
P01HL-19242-02 0004 (HEPA) BROOKER, GARY. Study of vascular smooth
muscle-Cyclic nucleotide metabolism in smooth muscle cultures
(human, rats).
P01HL-19242-02 0006 (HEPA) OULING, BRIAN. Study of vascular smooth
muscle-The contractile system of vascular smooth muscle (swine,
rats).
POI HL-1 9242-02 0007 (HEPA) WESTFALL, THOMAS C. Study of vascular
smooth muscle-NE release in and reactivity of vascular smooth
muscle (animals).
P01HL-19242-02 0008 (HEPA) PEACH, MICHAEL J. Study of vascular smooth
muscle-NE release in and reactivity of vascular smooth muscle (rats).
POI HL-1 9242-02 0009 (HEPA) SPERELAKIS, NICK. Study of vascular smooth
muscle -Electrophysiology of vascular smooth muscle (rats, chick emb-
ryo).
ROIHL-1 9246-03 (CVB) GROSSMAN, WILLIAM, PETER BENT BRIGHAM HOSPITAL.
721 HUNTINGTON AVENUE. BOSTON. MASS. Regression of cardiac
hypertrophy-Myocardial and renal (human)
ROIHL-19248-03 (AFY) DAUBENSPECK, JOHN A, DARTMOUTH MEDICAL
SCHOOL. DEPT OF PHYSIOLOGY. HANOVER. N H. Breathing pattern
variation and mechanical influences.
R01HL-19250-03 (MET) MUESING, RICHARD A, GEORGE WASHINGTON UNIVERSI-
TY. 2300 EYE STREET, N W, WASHINGTON. D C. Mechanism of plasma
cholesterol esterification (human).
R01HL-192S1-03 (CVB) ALEXANDER, NATALIE, UNIV OF SOUTHERN CALIFORNIA.
2025 ZONAL AVENUE, LOS ANGELES, CALIF. An index of sympathetic
activity in hypertension (rats).
ROIHL-1 9252-02 (PBC) FISCHER, GRACE M, BOCKUS RESEARCH INSTITUTE. 19TH
AND LOMBARD STREETS. PHILADELPHIA. PA. Vascular connective tis-
sue-Role in atherosclerosis (rabbits).
ROIHL-1 9255-03 (CVB) SEAMAN, GEOFFREY V, PROVIDENCE MEDICAL CENTER,
700 N E 47TH AVENUE. PORTLAND, OREG. Evaluation of diagnostic
clinical hemorrheology (human).
R01HL-19256-03 (CVA) COX, ROBERT H, BOCKUS RESEARCH INSTITUTE. 19TH &
LOMBARD STREETS. PHILADELPHIA, PA. Arterial baroreceptors in car-
diovascular control (dogs).
R01HI-192S7-03 (CVA) GALOSY, RICHARD A, UNIV OF TEXAS HLTH SCI CTR.
5323 HARRY HINES BOULEVARD, DALLAS. TEX. Cardiovascular adjust-
ment to behavioral stress (dog).
POI Hl-1 9259-03 (HEPA) HABER, EDGAR, MASSACHUSETTS GENERAL HOSP. FRUIT
STREET. BOSTON, MASS. Digoxin-specific antibody in human therapy.
POI HL-1 9259-03 0001 (HEPA) MARGOIIES, MICHAEL N. Digoxin-specific an-
tibody in human therapy-Primary structure of monoclonal antibodies
(rabbits).
P01HL-19259-03 0002 (HEPA) BURTON, JAMES A. Digoxin-specific antibody in
human therapy -Chemical semi-synthesis of digoxin-specific antibody
(rabbits).
POI HL-1 9259-03 0003 (HEPA) HABER, EDGAR. Digoxin-specific antibody in
human therapy -Synthesis of dogoxin-specific antibody in continuous
cell culture (human, sheep).
POI HL-1 9259-03 0004 (HEPA) SMITH, THOMAS W. Digoxin-specific antibody in
human therapy-Digitalis-specific antibodies pharmacological studies
(human, dogs, sheep).
POI HL-1 9259-03 0006 (HEPA) HABER, EDGAR. Digoxin-specific antibody in
human therapy -Core.
ROI HL-1 9267-02 (HEM) ABILDGAARD, CHARLES F, UNIV OF CALIFORNIA. DAVIS,
4301 X STREET. SACRAMENTO. CALIF. Serial comparative study of Von
Willebrand's disease (human).
ROlHl-19270.03 (HEM) JACKSON, CARL W, ST JUDE CHILDREN'S RES HOSP.
332 NORTH LAUDERDALE. MEMPHIS. TENN. Effects of erythropoiesis on
platelets and hemostasis (rats).
ROI HL-1 9272-03 (HEM) HOUGIE, CECIL, UNIV OF CALIFORNIA. SAN DIEGO, DEPT
OF PATHOLOGY, M-012, LA JOLLA. CALIF Studies on the Passovoy fac-
tor (human).
MS5S
PROJECT NUMBER AND INVESTIGATOR ADDRESS
564
R0)Hl-19275-03 (CVA) WILLIAMS, PATRICIA B, EASTERN VIRGINIA MED
SCHOOL. POST OFFICE BOX 1980, NORFOLK, VA. Characterization of
collateral blood vessels (dogs).
ROlHL-1 9278-03 (HEM) COILER, BARRY S, SUNY AT STONY BROOK DIV OF HEM
DEPARTMENT OF MEDICINE, STONY BROOK, N Y. Ristocetin induced
platelet aggregation (human).
ROlHL-19279-03 (CVB) KEM, DAVID C, UNIV OF OKUHOMA HLTH SCI CTR P 0
BOX 26901, OKUHOMA CITY, OKU. Intracellular action of aldosterone
in hypertension (human, rats).
ROIHl-19282-03 (HEM) KOSOW, DAVID P, RED CROSS BLOOD RES LAB 9312
OLD GEORGETOWN RD, BETHESDA, MO. Regulation of the activation of
human factor X.
R01HL-19287.03 (CVB) MUIRHEAD, ERNEST E, BAPTIST MEMORIAL HOSPITAL
899 MADISON AVENUE, MEMPHIS, TENN. The antihypertensive function
of the renal medulla (human, rats, rabbits).
ROlHL-19289-03 (RAD) lEHAN, PATRICK H, UNIVERSITY OF MISSISSIPPI 2500
NORTH STATE STREET, JACKSON, MISS. Assessment of infusion
methods for myocardial mapping (dogs).
ROlHl-1 9298-03 (CVA) DAWSON, CHRISTOPHER A, VETERANS ADMINISTRA-
TION CENTER, RESEARCH SERVICE - 151A, WOOD, WIS. Pulmonary
hemodynamics (dogs, cats).
R01HL-1 9299-03 (CVA) WITTENBERG, BEATRICE A, ALBERT EINSTEIN COLL OF
MED, 1300 MORRIS PARK AVENUE, BRONX, N Y. Myoglobin and oxygen
supply to heart and muscle cells (rats, pigeons).
RO)Hl-19307-03 (BM) KAPLAN, EDWARD L, UNIVERSITY OF MINNESOTA, BOX 94
MAYO, MINNEAPOLIS, MINN. Problems in prevention of rheumatic heart
disease (human).
R01HL-19316-03 (PTHA) RODEWALD, RICHARD D, UNIVERSITY OF VIRGINIA,
GILMER HALL, CHARLOTTESVILLE, VA. Study of glomerular permeability
(fish, turtle, frog, chordates, Crustacea).
ROlHl-l 9320-03 (PHY) SEVERS, WALTER B, PENNSYLVANIA STATE UNIVERSITY,
DEPARTMENT OF PHARMACOLOGY, HERSHEY. PA. Angiotensin neu'
ropharmacology-Relationship to sodium.
R01HL-1 9322-03 (HEM) MATSCHINER, JOHN T, UNIVERSITY OF NEBRASKA
42ND AND DEWEY AVENUE, OMAHA, NEBR. Role of pituitary hormones
in the action of vitamin K (rats).
R01HL-1 9323-03 (HEM) STEINER, MANFRED, MEMORIAL HOSPITAL, PROSPECT
STREET, PAWTUCKET, R I. Studies of platelet microtubule protein.
R01HL-1 9324-02 (HEM) NATTA, CLAYTON L, COLUMBIA UNIVERSITY, 630 WEST
168TH STREET, NEW YORK, N Y. Mechanisms of the inhibition of sick-
ling by DBA (human).
R01HL-1 9325-03 (PHRA) WELLS, JACK N, VANDERBILT UNIVERSITY. DEPARTMENT
OF PHARMACOLOGY, NASHVILLE, TENN. Phosphodiesterase inhibition
and muscle contraction.
R01HL-1 933 1-03 (HEM) JONES, WARREN C, JR, UNIVERSITY OF VIRGINIA DE-
PARTMENT OF CHEMISTRY, CHARLOHESVILLE, VA. Hirudin isolation
and utilization (leeches).
R01HL-19333-03 (HEM) BOGGS, DANE R, UNIVERSITY OF PinSBURGH TERRACE
AND DESOTO STREETS, PIUSBURGH, PA. Hematopoietic chimerism
(mice, monkey).
R01HL-I9341-03 (RAD) SPENCER, MERRILL P, INST OF APPLIED PHY & MED, 556
18TH AVENUE. SEATTLE, WASH. Ultrasonic detection of the atheros-
clerotic plaque.
ROIHL-19343-03 (CVB) RANDALL, DAVID C, UNIVERSITY OF KENTUCKY PHY &
BIOPHYSICS DEPARTMENT, LEXINGTON, KY. Behavioral influences on
cardiac contractility (monkeys)
R01HL-I93S0-02 (SGYB) RICHARDSON, PETER 0, BROWN UNIVERSITY. BOX G,
PROVIDENCE, R I. Prevention of thrombosis by applied electric fields
(sheep).
R01HL-1 9352-03 (CVA) JOHNSON, CHARLES E, DUKE UNIVERSITY, POST OFFICE
BOX 3823, DURHAM, N C. Respiratory heat and water loss in
neonates.
P50HL-1 9362-02 (SRC) MC GILL, HENRY C, JR, UNIVERSITY OF TEXAS 7703
FLOYD CURL DRIVE, SAN ANTONIO. TEX. A/S SCOR -Atherosclerosis in
nonhuman primates.
P50HL-1 9362-02 0001 (SRC) MOTT, GLEN E. A/S SCOR-Atherosclerosis in nonhu-
man primates-Effects of infant nutrition on atherosclerosis (baboons)
PSOHL- 1 9362-02 0002 (SRC) MASORO, EDWARD J. A/S SCOR Atherosclerosis
in nonhuman primates -Infant caloric intake, adipose tissue develop-
ment and atherosclerosis (baboon).
PSOHL-1 9362-02 0003 (SRC) KRAEMER, DUANE C. A/S SCOR- Atherosclerosis in
nonhuman primates -Heritability of characters related to atherosclero-
sis (baboons).
P50HI- 1 9362-02 0004 (SRC) KRAEMER, DUANE C. A/S SCOR Atherosclerosis in
nonhuman primates-Selective breeding for characters related to
atherosclerosis (baboons).
P50HI-19362-02 0005 (SRC) KRAEMER, DUANE C. A/S SCOR -Atherosclerosis in
nonhuman primates -Hybridization to produce primate model of
atherosclerosis (baboon. Rhesus).
P50HI-1 9362-02 0006 (SRC) ROGERS, WALTER R. A/S SCOR -Atherosclerosis in
nonhuman primates-Effects of cigarette smoking on atherosclerosis
(baboon).
PSOHl-1 9362-02 0007 (SRC) ROGERS, WALTER R. A/S SCOR- Atherosclerosis in
nonhuman primates -Behavior type, cigarette smoking and atheros-
clerosis (baboon).
PSOHL- 19362-02 0008 (SRC) JOHANSON, WALDEMAR G. A/S SCOR AtberoS
clerosis in nonhuman primates -Lung structure and function in
cigarette smoking (baboon).
P50HL-1 9362-02 0009 (SRC) MOTT, GLEN E. A/S SCOR-Atherosclerosis In nonhu
man primates-Cholesterol metabolism and intestinal microflora
(baboon).
PSOHL- 19362-02 0010 (SRC) SAMUELS, ALLAN I. A/S SCOR-Atherosclerosis in
nonhuman primates-Antihypertensive therapy-Atherogenesis in experi-
mental hypertension (baboon).
PSOHL- 19362-02 0011 (SRC) MITCHELL, DANIEL S. A/S SCOR Atherosclerosis in
nonhuman primates -Chronic hypertension induced by operant condi-
tioning techniques (baboon).
PSOHL- 19362-02 0012 (SRC) MCGILL, HENRY C, JR. A/S SCOR Atherosclerosis
in nonhuman primates -Induction of chronic hypertension by salt load-
ing (baboon).
P50HI-19362-02 0013 (SRC) MOTT, GLEN E. A/S SCOR-Atherosclerosis in nonhu-
man primates -Core laboratory-Lipid biochemistry (baboons).
PSOHL- 19362-02 0014 (SRC) COELHO, ANTHONY M. A/S SCOR Atherosclerosis
in nonhuman primates-Core laboratory-Behavior observation and
manipulation (baboon).
P50HL-1 9362-02 0015 (SRC) MOGUL, HENRY C, JR. A/S SCOR Atherosclerosis
in nonhuman primates-Core laboratory-Pathology and morphometry
(baboons).
PSOHL-1 9362-02 0016 (SRC) CAREY, KENNETH D. A/S SCOR Atherosclerosis in
nonhuman primates-Core laboratory-Animal services (baboon)
P50HL-1 9362-02 0017 (SRC) MCMAHAN, C ALEX. A/S SCOR Atherosclerosis in
nonhuman primates -Core laboratory-Data management, statistical
analysis.
ROlHL-1 9366-03 (GMB) BANK, NORMAN, MONTEFIORE HOSP & MED CTR, 111
EAST 210 STREET, BRONX. N Y. Renal Starling forces in experimental
conditions (rats, rabbits).
ROlHL-19370-03 (CVB) HARRIS, THOMAS R, VANDERBILT UNIVERSITY. B-3211.
MEDICAL CENTER. NASHVILLE. TENN. Coronary capillary exchange-The
effects of ischemia (dogs, sheep).
R01HL-1 9374-03 (CVB) MARSHALL, GARLAND R, WASHINGTON UNIVERSITY, 660
S EUCLID, ST LOUIS, MO. Pharmacology of kinins in cardiovascular
disease (rats, rabbits).
R01HL-19378-03 (PTHA) BERKOFF, HERBERT A, UNIVERSITY HOSPITALS. 1300
UNIVERSITY AVENUE. MADISON. WIS. Relation of mitochondrial
changes to cardiac failure (dogs. rats).
ROlHL-19379-03 (PTHA) HOYT, RICHARD F, JR, BOSTON UNIVERSITY SCH OF
MEDIC. 80 EAST CONCORD STREET. BOSTON. MASS. Characterization
of small-granule cells in the lung (mammals).
ROtHL-19381-03 (EVR) FABRICANT, CATHERINE G, CORNELL UNIVERSITY DE
PARTMENT OF MICROBIOLOGY. ITHACA. N Y. Pathogenesis of viral in-
duced atherosclerosis (human, chicken).
R01HL-19391-03 (CVA) YELLIN, EDWARD I, ALBERT EINSTEIN COLLEGE OF MED
1300 MORRIS PARK AVENUE, BRONX, N Y. Dynamic determinants of
left ventricular filling (dogs).
R01HL-19392-03 (BBCB) SEITER, CHARLES H, UNIV OF SOUTHERN CALIFORNIA
UNIVERSITY PARK. LOS ANGELES, CALIF. Spectroscopic studies of
respiratory metalloproteins.
R01HL-1 9394-03 (MET) HUXTABLE, RYAN J, UNIVERSITY OF ARIZONA. DEPT OF
PHARMACOLOGY, TUCSON, ARIZ. Biochemistry and regulation of tau-
rine in the heart (rats, guinea pigs, cats).
R01HL-I9398-03 (CVA) ETTINGER, PHILIP O, NEW JERSEY MEDICAL SCHOOL 100
BERGEN STREET, NEWARK, N J. Regional conduction abnormalities
and arrhythmias (dogs).
R01HL-19399-02 (NTN) GAMBAl, DAVID, CREIGHTON UNIVERSITY. 2500
CALIFORNIA STREET, OMAHA, NEBR. Atherosclerosis-Early events and
regression factors (rats).
R01HL- 1 9406-03 (RAD) BERGUER, RAMON, WAYNE STATE UNIVERSITY, 540 EAST
CANFIELD AVENUE, DETROIT, MICH. Grading of atherosclerosis by CVK
doppler ultrasound (human, dogs).
R01HL-19410-03 (AFY) WHIPP, BRIAN J, HARBOR GENERAL HOSPITAL. 1000
WEST CARSON STREET, TORRANCE, CALIF. Dynamic interrelations un-
derlying exercise hyperpnea (human).
R01HL- 194 14-03 (SGYA) GOTT, VINCENT L, JOHNS HOPKINS HOSPITAL 601
NORTH BROADWAY, BALTIMORE, MD. Protection of myocardium during
cardiac surgery (dogs, cats, human).
ROIHL-19419-03 (SGYB) HORBETT, THOMAS A, UNIVERSITY OF WASHINGTON
DEPT OF CHEMICAL ENGR,, SEAHLE, WASH. Cellular interactions with
foreign materials (mammals).
R01HL-1 9423-03 (CVA) BIRNBAUMER, lUTZ, BAYLOR COLLEGE OF MEDICINE
1200 MOURSUND AVENUE, HOUSTON, TEX. Catecholamine action on
the heart (cats. rats).
ROIHl-1 9425-03 (CVB) BOVE, ALFRED A, TEMPLE UNIVERSITY. 3400 N BROAD
STREET, PHIUDELPHIA, PA. Cardiac function in hypertrophy (dog)
ROlHL-1 9428-03 (CVB) ANDERSON, GUNNAR H, JR, STATE UNIVERSITY
HOSPITAL, 750 EAST ADAMS STREET, SYRACUSE, N Y. Role of an-
giotensin sensitivity in renin release (human).
R01 HI- 19429-03 (PTHA) STOSSEl, THOMAS P, MASSACHUSETTS GENERAL
HOSPITAL. FRUIT STREET. BOSTON, MASS. Phagocytosis-lngestion in
alveiolar macrophages (rabbits).
R01HL-1 9430-03 (HED) LAYTON, WILLIAM M, JR, DARTMOUTH MEDICAL
SCHOOL, DEPARTMENT OF ANATOMY, HANOVER, N H. Congenital heart
malformations and situs inversus (mice).
ROIHL-1 943 1-03 (CVA) UPPMANN, MORTON, NEW YORK UNIVERSITY. 550
FIRST AVENUE, NEW YORK, N Y. Regional mucociliary transport in the
human lung.
R01HL-1 9449-03 (CVA) DANTZKER, DAVID R, UNIVERSITY OF MICHIGAN 1405
EAST ANN STREET, ANN ARBOR, MICH. Gas exchange in acute respira-
tory failure.
ROIHL-1 945 1-03 (CVB) DODGE, HAROLD T, UNIVERSITY OF WASHINGTON
SCHOOL OF MEDICINE, SEATTLE, WASH. Functional characteristics of
the left heart.
R01HL-194S1-03 0001 (CVB) DODGE, HAROLD T. Functional characteristics of
the left heart-Ventricular performance using epicardial radiopaque
markers (human).
R01HL-19451.03 0003 (CVB) STEWART, DOUGLAS K. Functional characteristics
of the left heart-Left ventricular segmental contraction (human,
dogs).
R01HL.19451-03 0004 (CVB) BROWN, B GREG. Functional characteristics of
the left heart -Quantitative coronary arteriography (human)
ROIHL-1 9454-02 (CVB) CHIEN, SHU, COLUMBIA MEDICAL CENTER. 630 WEST 168
STREET. NEW YORK, N Y. Rheological factors in transport across ar-
terial wall (dogs).
ROlHL-1 9455-03 (PHY) JOYNER, WILLIAM I, UNIVERSITY OF NEBRASKA, 42N0
AND DEWEY, OMAHA, NEBR. Role of endothelial cells in vascular
permeability (tissue culture).
ROIHL-1 9456-03 (BBCA) SMITH, LINDA L, MEDICAL COLLEGE OF GEORGIA, DEPT
CELL & MOLECUUR BIOLOGY . AUGUSTA. GA. Immunoglobulins as-
sociated with serum hyperviscosity (human).
ROIHL-1 9459-03 (BBCB) POWNALL, HENRY J, METHODIST HOSPITAL, MAIL STAT
A-601 MED DEPT, HOUSTON. TEX. Dynamics of atherogenesis and
lipoprotein formation (human, rabbit).
ROlHL-19460-03 (CVA) PINTO, JOHN G, UNIV OF CALIFORNIA. SAN DIEGO. MAIL
CODE M-005. U JOLU, CALIF Mechanics of the papillary muscle and
the left ventricle (cats, rabbits).
R01HL-19461-03 (CVA) COULSON, lORNE R, TEMPLE UNIVERSITY, 3400 N
BROAD STREET, PHIUDELPHIA, PA. Myocardial energetics in hyper-
trophy and heart failure (rabbits).
ROIHL-1 9463-02 (GMB) OKEN, DONALD E, VIRGINIA COMMONWEALTH UNIV,
1200 EAST BROAD STREET, RICHMOND, VA. Pathophysiology of acute
renal failure (rats).
565
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19467-03 (CVR) BAROIR, A ClIfFORD. HARVARD MEDICAL SCHOOL. 2b
SHAITUCK SIREEl, BOSION. MASS Rogulation ol blood piessuce (tals.
do|s)
l94tl-03 (BBCB) OIDFIEID, ERIC, UNIVERSITY OF IlllNOIS, DEPARIMEN1
OF CHEMISIRY. URBANA. ILL High (leld NMR studies o( respifalorv
piotems (human, hoise. Iish. miciobes)
19485-03 (CVA) BRIOOS, F NORMAN. MEDICAL COLLEGE OF VIRGINIA.
1200 EAST BROAD SIREEl. RICHMOND, VA Calcium uptake by noimal
and tailed caidiac AlPase (dogs)
.19486-03 (CVB) HOOGKIN, BRIAN C. BIOMEDICAL RESEARCH INSTITUTE.
246 DEERING AVENUE. PORTLAND. MAINE Oipole moment measure
meni ot caidiac mass (labbils, pigs)
.19487-03 (CVB) MOE, GORDON K, MASONIC MEDICAL RESEARCH LAB.
2150 BLEECKER STREET, UTICA. N Y Cardiac actions ol digitalis
(dogs, cats)
.19488-03 (BMT) EISENTHAl. KENNETH B, COLUMBIA UNIVERSITY. BOX
616 HAVEMEYER HALL, NEW/ YORK, N Y Picosecond laser studies ol
heme proteins
19491-03 (BBCA) FISH, WAYNE W, MED UNIV OF SOUTH CAROLINA, OE
PARTMENT OF BIOCHEMISTRY, CHARLESTON, S C. Mechanism of non
storage and mobilization by ferritin (horse)
19SI4-03 (MCHA) DYCKES, DOUGLAS F, UNIVERSITY OF HOUSTON, 4800
CALHOUN, HOUSTON, TEX Proteinase inhibitor model with clinical
potential
19517-03 (PHRA) BURTON, JAMES A, MASSACHUSEnS GENERAL
HOSPITAL, 32 FRUIT STREET. BOSTON. MASS. Synthesis of inhibitors
for the study of renal renin (dogs, monkeys).
19532-01 (BIO) STERN, ARNOID, NEW YORK UNIVERSITY. DEPARTMENT OF
PHARMACOLOGY. NEW YORK. N Y Oxygen toxicity in the red cell
(human)-
19537-03 (RAD) MIUER, JAMES G, WASHINGTON UNIVERSITY. SKINKER &
LINOELL, ST LOUIS. MO. Detection of myocardial injury with ultrasound
(dogs).
19538-03 (MCHA) AIMQUIST, RONAID G, SRI INTERNATIONAL. 333
RAVENSWOOD AVENUE. MENLO PARK, CALIF. Synthesis of potential an-
tihypertensive agents.
19539-03 (PTHA) CAMPBEll, WAllACE G, JR, EMORY UNIVERSITY. 705
WOODRUFF MEMORIAL BLDG. ATLANTA, GA. Pathology of hypertensive-
associated arteritis (rabbits)
19567-03 (SSS) HACKETT, THOMAS P, MASSACHUSETTS GENERAL
HOSPITAL. FRUIT STREET, BOSTON, MASS. Impact of emotion on coro-
nary arteries (human).
19568-03 (EXP) SHAPIRO, DAVID, UNIVERSITY OF CALIFORNIA, NEU-
ROPSYCHIATRIC INSTITUTE, LOS ANGELES, CALIF. Hypertension -Analy-
sis of drug and behavioral therapies (human).
19573-01 (YIP) BOSIN, TAIMAGE R, INDIANA UNIVERSITY, 306 MYERS
HALL. BLOOMINGTON, IND. Studies on pulmonary serotonin (mice).
19584-01 (YIP) GRANT, MARGARET M, HARVARD UNIVERSITY, 665
HUNTINGTON AVENUE, BOSTON, MASS. Alveolar macrophage responses
to toxic particle exposure (guinea pigs, human).
19594-01 (YIP) MANDEl, RICHARD, BOSTON UNIVERSITY SCH OF MEO. 80
E CONCORD STREET. BOSTON. MASS. Tropocollagen and tropoelastin
uptake in lung cells (human).
19601-01 (GMB) BETTICE, JOHN A, CASE WESTERN RESERVE UNIV. 2119
ABINGTON ROAD. CLEVELAND. OHIO. Cardiac response to chronic
metabolic acidosis (rats).
.19605-01 (YIP) VORE, MARY E, UNIVERSITY OF CALIFORNIA, OEPT OF
PHARMACOLOGY, SAN FRANCISCO, CALIF. Lipid requirement of the
lung mono-oxygenase system (rabbits).
.19619-01 (YIP) ABRAHAM, JERROID I, UNIV OF CALIFORNIA, SAN DIEGO,
SCHOOL OF MEDICINE, M-012, LA JOLLA, CALIF Sem and x ray analy-
sis in human pulmonary pathology.
19628-03 (CVA) PARK, BYUNG H, CHILDREN'S HOSPITAL, 219 BRYANT
STREET, BUFFALO. N Y. Mechanisms of pulmonary alveolar proteinoses
(human, rats).
19633-02 (SSS) CHVAPIl, MHOS, ARIZONA MEDICAL CENTER, DEPT OF
SURGERY, TUCSON, ARIZ. Pathogenesis and pharmacology of lung
fibrosis (rats, rabbits).
19639-02 (PHY) SZABO, GABOR, UNIVERSITY OF TEXAS. DEPT OF
PHYSIOLOGY & BIOPHYS. GALVESTON. TEX. Permeability transients of
carriers, channels and heart.
19644-03 (END) MUIROW, PATRICK J, MEDICAL COLLEGE OF OHIO, C S
10008, TOLEDO, OHIO. Etiological factors in hypertension (human,
dogs, rats).
19646-03 (HEM) JAVID, JAMSHID, NEW YORK UNIVERSITY. 550 FIRST
AVENUE. NEW YORK. N Y. An immunologic study of hemoglobin varia-
tion in man.
19647-03 (SSS) KATZ, SIDNEY, RESEARCH INSTITUTE. 10 WEST 35 STREET.
CHICAGO. ILL. Therapeutic aerosols.
.19648-03 (CVB) lESCH, MICHAEl, NORTHWESTERN UNIVERSITY, 303 EAST
CHICAGO AVENUE, CHICAGO, ILL Myocardial protein degradation
(dogs, rabbits).
19651-03 (PTHA) GlEZEN, WIlllAM P, BAYLOR COLLEGE OF MEDICINE.
1200 MOURSUND AVENUE. HOUSTON. TEX. Host factors in pathogene-
sis of respiratory disease (human, hamsters).
19653-03 (PHRA) FREER, RICHARD J, MEDICAL COLLEGE OF VIRGINIA.
MCV STATION. RICHMOND. VA. Circulatory system effects of angioten-
sin analogs (rats).
19654-03 (BIO) PROUGH, RUSSEll A, UNIVERSITY OF TEXAS. 5323
HARRY HINES BLVD. DALLAS. TEX. Biochemical-pharmacological
evaluation of lung cells (rabbits).
.19668-03 (SSS) BHATNAGAR, RAJENDRA S, UNIVERSITY OF CALIFORNIA.
SCH OF OENTISTRY-630 SCIENCES. SAN FRANCISCO. CALIF
Biochemistry of lung connective tissue (rats).
19669-03 (SSS) WEINHOID, PAUl A, UNIVERSITY OF MICHIGAN. 3014 AD-
MINISTRATION BUILDING. ANN ARBOR. MICH. Lung organ culture and
surfactant biosynthesis (adult and fetal rats).
19673-03 (SGYA) BAUE, ARTHUR E, YALE UNIVERSITY. 333 CEDAR
STREET. NEW HAVEN, CONN. Surgical aspects of shock and hypoxia
(dogs, monkeys, rats).
19674-02 (CVA) FRIEDMAN, JUIIUS J, INDIANA UNIVERSITY, 1100 WEST
MICHIGAN STREET, INDIANAPOLIS, IND. Electrolyte permeability of sin-
gle capillaries (frogs).
PROJECT NUMBER AND INVESTIGATOR ADDRESS
ROIHl. I967S-02 (RAD) BOOKSTEIN, JOSEPH J. UNIVERSITY OF CALIFORNIA. ?25
WE SI DICKINSION SIHIEI SAN DIFGO. CALIF Coronary pharmacoan
giography
R01Hl.19676-0a (CVA) KING, RICHARD J. UNIVERSITY Of TEXAS. /703 FIOYD
CURl DRIVE. SAN ANIONIO. TEX Phyjico chemical interactionj in pilT
monary surfactant
ROIHl-19677-03 (CVB) MORRIS, THOMAS W, UNIV OF ROCHESTER MEDICAL
CTR. DIAGNOSTIC RADIOIOCY BOX 648. ROCHESTER, N Y Venous
structure and lunction (dogs)
ROIHl-19678-01 (CVA) BAKER, lEE E, UNIVERSITY OF TEXAS. AUSTIN. TEX Ouan
tilication ol intrathoracic fluid by impedance (human, dogs)
R01HH9680-01 (EXP) lAVKlER, JAMES E, UNIVERSITY OF TENNESSEE. DEPART
MENT OF PSYCHOLOGY. KNOXVILLE. TENN Cardiac correlates of
behavioral stress in animals (dog)
ROIHl-19684-03 (SSS) ROSE, GEORGE G, UNIV OF TEXAS HLTH SCI CTR. 6516
JOHN FREEMAN AVENUE. HOUSTON, TEX Histotypic lung culture in cir
cumfusion systems (mice)
R01HH9685-03 (SSS) CASTOR, C WIlllAM, UNIVERSITY OF MICHIGAN. R4633
KRESGE MED RES BLDG. ANN ARBOR. MICH Pathogenesis of indam
mation ol the lung (guinea pigs)
ROIHl- 19700-03 (SSS) WANG, CHIU-SEN, SYRACUSE UNIVERSITY. 232 HINDS
HALL SYRACUSE. N Y Deposition ol hygroscopic aerosols (models)
ROIHl-l 9704-03 (SSS) WIISON, ARCHIE F, UNIV OF CALIFORNIA. IRVINE. 101
CITY DRIVE SOUTH. ORANGE, CALIF, aerosol therapy (models, dogs.
human).
ROIHl-1 97 11-03 (SSS) YOSHIDA, TAKESHI, UNIVERSITY OF CONNECTICUT. OE
PARTMENT OF PATHOLOGY. FARMINGTON. CONN Lymphokines in pul-
monary granulomas (guinea pigs)
ROIHl-19715.02 (SSS) SWIFT, DAVID I, JOHNS HOPKINS UNIVERSITY. 615 NORTH
WOLFE STREET. BALTIMORE. MD Respiratory tract deposition of hygro
scopic aerosols (dogs, human)
POIHl-19717-02 (HEPA) FRANZBIAU. CARl, BOSTON UNIVERSITY. 80 EAST CON
CORD STREET. BOSTON. MASS. Response of the lung to injury
POIHl-19717-02 0001 (HEPA) FRANZBIAU, CARL Response of the lung to in
jury-Lung elastic tissue (animals)
POIHl-19717-02 0002 (HEPA) GONNERMAN, WAYNE. Response of the lung
to injury-Prolyl hydroxylase, lysyl hydroxylase and lung collagen
biosynthesis (rabbits)
POIHl-19717-02 0003 (HEPA) STONE, PHIlIP J. Response of the lung to injury-
The role of elastolysis in emphysema (hamsters, rabbits),
POIHl-19717-02 0004 (HEPA) KAGAN, HERBERT M. Response of the lung to
injury-Regulatory and physical-chemical properties of lung lysyl ox-
idase (animals).
POlHl-1 97 17-02 0005 (HEPA) KAGAN, HERBERT M. Response of the lung to
injury -Studies on proteolysis and lung disease (human, animals)
P01 HI- 197 17-02 0006 (HEPA) SCHMID, KARl. Response of the lung to injury
Glycosaminoglycans and proteoglycans of the lung (human, rats, ham-
sters).
POIHl-19717-02 0007 (HEPA) POIGAR, PETER. Response of the lung to injury-
Cellular level studies of prostaglandinlike molecules (cattle).
POlHl-19717-02 0008 (HEPA) SNIDER, GORDON L Response of the lung to in.
jury-Experimental models of lung disease.
POIHl-19717-02 0009 (HEPA) KARIINSKY, JOEl B. Response of the lung to in.
jury-Time-dependent mechanical properties of lung connective tissues
(hamsters).
POlHl-19717-02 0010 (HEPA) KARIINSKY, JOEl B. Response of the lung to in
jury-Proteoglycans in lung function and structure (hamsters).
POIHl-19717-02 0011 (HEPA) KARIINSKY, JOEl B. Response of the lung to in.
jury -Physiological characterization of the elastase model (hamsters).
POlHl-1 97 17-02 0012 (HEPA) KARIINSKY, JOEl B. Response of the lung to in
jury-.Connective tissue biochemistry and enzyme injury of the lung
(hamsters).
POlHl-19717-02 0013 (HEPA) SNIDER, GORDON L Response of the lung to in.
jury-Handling of biologically active substances by the diseased lung
(guinea pigs).
POIHl-19717-02 0014 (HEPA) SNIDER, GORDON L Response of the lung to in.
jury-Stereology of epithelialized bronchi in evolving elast
emphysema (hamsters).
POIHl-19717-02 0015 (HEPA) SNIDER, GORDON I. Response of the lung to in-
jury-Chronic bronchitis and emphysema (hamsters).
POIHl-19717-02 0016 (HEPA) CENTER, DAVID. Response of the lung to injury-
The alveolar macrophage in elastase emphysema (guinea pigs, ham-
sters).
POlHl-1 97 17-02 0018 (HEPA) SNIDER, GORDON L Response of the lung to in-
jury-Lung mechanics and connective tissue composition in human
emphysema.
POIHl-19717-02 0019 (HEPA) SNIDER, GORDON I. Response of the lung to in-
jury..Animal model of fibrosing alveolitis (hamsters, guinea pigs. rab.
bits).
P01 HI- 197 17-02 0020 (HEPA) SNIDER, GORDON I. Response of the lung to in.
jury-Recording of lung sounds in animal models of disease (animals).
POIHl-19717-02 0021 (HEPA) SNIDER, GORDON I. Response of the lung to in-
jury-Gallium lung scans in fibrosing alveolitis (hamsters).
POIHl-19717-02 0022 (HEPA) AlBRIGHT, JOHN T. Response of the lung to in-
jury-Localization of enzymes and sites of action in experimental
emphysema (hamsters).
POIHl-19717-02 0023 (HEPA) BRODY, JEROME S. Response of the lung to inju-
ry-Postnatal lung development-Cells, connective tissue and physiology
(animals).
POIHl-19717-02 0024 (HEPA) BRODY, JEROME S. Response of the lung to inju-
ry-Formation of lung alveoli (rats).
POlHl-19717-02 0025 (HEPA) BRODY, JEROME S. Response of the lung to inju
ry-Role of oxygen in regulation of lung growth and development
(rats).
POIHl-1 97 17-02 0026 (HEPA) BRODY, JEROME S. Response of the lung to inju-
ry-Protein depletion and postnatal lung development (rats).
POlHl-19717-02 0027 (HEPA) BRODY, JEROME S. Response of the lung to inju.
ry-Hormone control of lung growth and development (rats).
POl HI- 197 17-02 0028 (HEPA) BRODY, JEROME S. Response of the lung to inju
ry-Compensatory growth of the lung following pneumonectomy
(rabbits).
POIHl-19717-02 0037 (HEPA) MATHE, AlEKSANDER A. Response of the lung
to injury-Catecholamines. prostaglandins and nucleotides in pulmona.
ry function (animals).
PROJECT NUMBER AND INVESTIGATOR ADDRESS
566
P01HL-19717
POlHl-19717-
POlHl-19717
POIHl.
POIHl-
POIHI-
POIHL-
POIHI-
ROIHL-
19717-
19717
19717-
19717
19717
19720
R01HL-I9721
R01HL-19722
R01HI-1972S
ROlHL-19731-
R01HL-19732
ROIHl-19733-
POlHl-19737
P01HL-19737
P01HL-19737
P01HH9737
POIHl-19737.
POIHl-19737
POIHl-19737
P01H1.19737
POIHl-19737
POlHl-19737
POIHl-19737
POIHL-19737
POIHL
POIHL
POIHl
POIHL
ROIHL
19737
.-19737
19737
.-19737
-19741
ftOIHL- 19746
ROlHl-19752
ROIHl
ROIHL-
19760
19767
ROIHL-19768
R01HL-19772
02 0038 (HEPA) GAENSLER, EDWARD A. Response of the lung
to inju(ye-lnterstitial lung disease -Clinical, pathologic and
epidemiologic.
■02 0039 (HEPA) GAENSLER, EDWARD A. Response of the lung
to injury-Lung scanning in alveolitis and asbestolic interstitial pneu-
monia (human, animal).
02 0040 (HEPA) GAENSLER, EDWARD A. Response of the lung
to injury-lmmunosuppressive drugs in usual interstitial pneumonia
(human).
02 0041 (HEPA) GAENSLER, EDWARD A. Response of the lung
to injury-Cellular immunity in interstitial lung disease (human).
■02 0043 (HEPA) GAENSLER, EDWARD A. Response of the lung
to injury-Asbestosis as a model of usual interstitial pneumonia
(human).
02 0044 (HEPA) MURPHY,. Response of the lung to injury-Lung
sound analysis (human).
■02 0045 (HEPA) FRANZBLAU, CARI. Response of the lung to inju-
ry-Ultrasound studies (human, hamsters).
•02 0046 (HEPA) GAENSLER, EDWARD A. Response of the lung
to injury-Bioengincering section.
■03 (SSS) GIRI, SHRI N, UNIVERSITY OF CALIFORNIA, DEPT OF
PHYSIOLOGICAL SCIENCES, DAVIS, CALIF. Evaluation of anfi-fibrotic
agents in pulmonary fibrosis (rats).
■03 (SSS) WEISSMANN, GERALD, NEW YORK UNIVERSITY 550
FIRST AVENUE, NEW YORK, N Y. Lung inflammation-Lysosomal
proteases and liposomes (human, rabbits).
■03 (SSS) WISSLER, EUGENE H, UNIVERSITY OF TEXAS, DEPT OF
CHEM ENGINEERING. AUSTIN, TEX. Aerosol growth in the respiratory
system (models).
03 (SSS) JACOB, HARRY S, UNIV OF MINNESOTA HOSPS, MAYO BOX
480, MINNEAPOLIS, MINN. Complement induced pulmonary injury
(dogs, rabbits, sheep).
03 (SSS) KANG, ANDREW H, RESEARCH SERVICE, 1030 JEFFER-
SON AVENUE, MEMPHIS, TENN. Collagen in interstitial fibrosis of lung
(human).
■03 (SSS) BOROS, DOV L, WAYNE STATE UNIVERSITY. 540 E CAN-
FIELD, DETROIT, MICH. Lymphokines in pulmonary granulomatous in-
flammation (mice).
■03 (SSS) DAWSON, CHRISTOPHER A, VETERANS ADMINISTRATION
CENTER, RESEARCH SERVICE - 151A, WOOD, WIS. Absorption of an-
tigen through inflamed lungs (rabbits).
-02 (HEPA) FORSTER, ROBERT E, UNIVERSITY OF PENNSYLVANIA
DEPARTMENT OF PHYSIOLOGY, PHILADELPHIA, PA. Cellular and molecu-
lar aspects of respiratory physiology,
-02 0001 (HEPA) FISHER, ARON B. Cellular and molecular aspects
of respiratory physiology -Fatty acid metabolism in type II alveolar
cells (rats).
■02 0002 (HEPA) ARONSON, J F. Cellular and molecular aspects
of respiratory physiology -Airway smooth muscle in health and disease
(human, animals).
■02 0003 (HEPA) ARONSON, J F. Cellular and molecular aspects
of respiratory physiology -Cortisol-dependent alterations in lung type II
cells (rats).
02 0004 (HEPA) FORSTER, ROBERT E. Cellular and molecular
aspects of respiratory physiology-Rapid reactions and erythrocyte
exchanges of blood during respiratory transport.
-02 0005 (HEPA) CRANDALL, EDWARD D. Cellular and molecular
aspects of respiratory physiology-Interaction of respiratory exchanges
and blood gas parameters (human, animals).
-02 0006 (HEPA) DELIVORIA-PAPADOPUOLOS, MARIA . Cellu
lar and .-nolecular aspects of respiratory physiology-Tissue oxygenation
and mitochondrial respiratory activity (sheep).
■02 0007 (HEPA) FORSTER, ROBERT E. Cellular and molecular
aspects of respiratory physiology-Average oxygen tension of tissue
using radioisotopes (dogs).
■02 0008 (HEPA) FORSTER, ROBERT E. Cellular and molecular
aspects of respiratory physiology-Kinetics of movement of acid
metabolites from cell to capillary blood (dogs).
-02 0009 (HEPA) COBURN, RONALD F. Cellular and molecular
aspects of respiratory physiology-Regulation of tissue oxygen tension
and body carbon monoxide stores (human, dogs).
-02 0010 (HEPA) CRANDALL, EDWARD D. Cellular and molecular
aspects of respiratory physiology-Effects of pulsatile flow and volume
on capillary exchanges (dogs, rats).
-02 0011 (HEPA) LAHIRI, SUKHAMAY. Cellular and molecular
aspects of respiratory physiology-Chemical and metabolic factors on
peripheral chemoreceptor activity (cats).
-02 0012 (HEPA) ITADA, NOBUTOMO. Cellular and molecular
aspects of respiratory physiology -Mass spectrometer facility.
-02 0013 (HEPA) STOREY, BAYARD T. Cellular and molecular
aspects of respiratory physiology-Cell metabolism analytical facility.
■02 0014 (HEPA) KLEINZELLER, ARNOST. Cellular and molecular
aspects of respiratory physiology -Cell separation facility.
■02 0015 (HEPA) FORSTER, ROBERT E. Cellular and molecular
aspects of respiratory physiology-Administrative core unit.
-03 (SSS) CASSELl, GAIL H, UNIVERSITY OF ALABAMA, UNIVERSITY
STATION, BIRMINGHAM, ALA. Murine CRD-A model of chronic pulmona-
ry inflammation (mice, rats).
-03 (SSS) LIN, HSIU-SAN, WASHINGTON UNIVERSITY, 660 SOUTH
EUCLID, ST LOUIS, MO. Proliferation and differentiation of alveolar
macrophages (mice, hamsters).
■03 (SSS) GROSS, IAN, DEPARTMENT OF PEDIATRICS, 333 CEDAR
STREET, NEW HAVEN, CONN. Phospholipid synthesis by fetal lung in
organ culture (rats).
1-01 (BM) RICHARDS, N MARK, DEPARTMENT OF MEDICINE, BOX
6998, CHICAGO, ILL. Cellular immune responses of the lung.
-01 (HEM) SHAINOFF, JOHN R, LTHE CLEVELAND CLINIC FDN,
RESEARCH DIVISION, CLEVEUND, OHIO. Pathochemistry of fibrinogen
(humans).
■02 (CVA) FLOWERS, NANCY C, UNIVERSITY OF LOUISVILLE, 323
EAST CHESTNUT, LOUISVILLE, KY. Recording and analysis of low levels
cardiac signals (human, dogs).
■02 (PHRA) FASCO, MICHAEL J, NEW YORK DEPARTMENT OF
HEALTH. EMPIRE STATE PUZA, ALBANY, N Y. Role of warfarin
metabolism in antivitamin K activity (rats).
R01HL-1 9774-03 (SSS) COLLINS, FRANK M, TRUDEAU INSTITUTE, INC, POST OF
FICE BOX 59. SARANAC LAKE, N Y. Pathogenesis of chronic lung dis-
ease (rats, mice, bacteria).
R01HL-19777-03 (SSS) GOETZL, EDWARD J, ROBERT B BRIGHAM HOSPITAL, 125
PARKER HILL AVENUE, BOSTON, MASS. Regulation of hypersensitivity
in the lung (rats, guinea pigs, rabbits, human).
ROIHL-19779-03 (SSS) BAEHNER, ROBERT I, J W RILEY HOSP FOR CHILDREN
1100 WEST MICHIGAN STREET, INDIANAPOLIS, IND. Biochemical basis
of oxygen damage to lung cells (guinea pigs, rats).
R01HL-1 9782-02 (PHRA) LUCCHESI, BENEDICT R, UNIVERSITY OF MICHIGAN
M6322 MEDICAL SCIENCE BLDG I, ANN ARBOR, MICH. Pharmacologic
studies on the ischemic heart (dogs).
R01HL-I9791-02 (RAD) HODSON, CECIL J, YALE UNIVERSITY, 333 CEDAR
STREET, NEW HAVEN, CONN. Ultrasonic monitoring visceral blood ves-
sels.
R01HL-I9795-03 (SSS) ERICKSON, BRUCE W, ROCKEFELLER UNIVERSITY 1230
YORK AVENUE, NEW YORK, N Y. Synthesis of anaphylatoxic and leu-
cotactic peptides (human).
R01HL-I9806-03 (SSS) LYNN, WILLIAM S, DUKE UNIVERSITY. POST OFFICE BOX
3711, DURHAM. N C. Chemotactic control of airway phagocytes
(human, rabbits).
R01HL-I9818-02 (SGYB) ARCHER, GORDON L, VIRGINIA COMMONWEALTH UNIV
POST OFFICE BOX 92, RICHMOND. VA. Endocarditis on prosthetic heart
valves (rabbits, human).
ROIHl-19819-03 (SSS) WILLOUGHBY, WILLIAM F, JOHNS HOPKINS HOSPITAL
601 NORTH BROADWAY, BALTIMORE, MD. Mitogen induced interstitial
pneumonitis (rabbits).
R01HL-1 9820-02 (PBC) CIFONEILI, J ANTHONY, UNIVERSITY OF CHICAGO, 5825
SOUTH MARYWNO AVENUE, CHICAGO, ILL. The chemistry and biologi-
cal effects of heparin (Rhesus, human, other mammals).
ROIHl-1 9824-02 (COM) HELLUMS, JESSE D, RICE UNIVERSITY, POST OFFICE BOX
1892, HOUSTON, TEX. Mass transfer in the microcirculation.
R01HL-1982S-02 (CVB) BAGBY, SUSAN P, PORTLAND VA HOSPITAL. SAM
JACKSON PARK, PORTLAND, OREG. Renin-volume interactions in coarc-
tation hypertension (dogs).
ROIHl-19827-02 (CVA) BARTLETT, DONALD, JR, DARTMOUTH MEDICAL SCHOOL
PHYSIOLOGY DEPARTMENT, HANOVER, N H. Role of the upper airways
in the control of breathing (human, cats, dogs).
ROIHL-19829-02 (AFY) OTIS, ARTHUR B, UNIVERSITY OF FLORIDA, BOX J-274.
JHMHC. GAINESVILLE, FLA. Power output of breathing (human).
ROIHL- 1 9830-02 (CVB) HOLLIS, THEODORE M, PENNSYLVANIA STATE UNIVERSI-
TY, 416 LIFE SCIENCE I, UNIVERSITY PARK, PA. Shear to aortic
histamine synthesis and permeability (dogs).
ROIHl-19836-03 (SSS) GOODFRIEND, THEODORE I, VETERANS ADMIN
HOSPITAL, 2500 OVERLOOK TERRACE, MADISON. WIS. Kinin inhibitors
detected by use of receptors (cattle).
ROIHl-l 9839-09 (SSS) PAFFENBARGER, RALPH S, JR, BENS, 101 HAVIUNO
HALL. UNIVERSITY OF CALIFORNIA, BERKELEY, CALIF. Factors in youth
predisposing to chronic diseases (former college students)
ROIHL-1 9844-02 (SSS) ZEINER, ARTHUR R, UNIVERSITY OF OKLAHOMA, POST OF-
FICE BOX 26901, OKLAHOMA CITY, OKU. Behavioral control of essen-
tial hypertension (human).
R01HL-19848-02 (CVA) LINDIEY, BARRY D, CASE WESTERN RESERVE UNIV 2119
ABINGTON ROAD, CLEVEUND, OHIO. Contractile activation by rapid
temperature jumps (frogs).
ROIHL-1 9858-03 (TEC) WATSON, ROBERT I, UNIVERSITY OF MISSISSIPPI 2500
NORTH STATE STREET, JACKSON, MISS. UMMC-Blood pressure precur-
sors and consequences (human).
R0IHL-I98S9-03 (TEC) VAN DEN BERG, BARBARA J, UNIVERSITY OF CALIFOR-
NIA, SCHOOL OF PUBLIC HEALTH, BERKELEY, CALIF. Epidemiological
studies, precursors of hypertension (human).
ROIHL-1 9864-03 (TEC) KULIER, LEWIS H, UNIVERSITY OF PIHSBURGH A 710
CRABTREE HALL, PinSBURGH, PA. Blood pressure of children and
young adults.
ROIHL-1 9864-03 0001 (TEC) ROGERS, KENNETH. Blood pressure of children
and young adults-Follow up of students from Oormont, Pennsylvania
ROIHL-1 9864-03 0002 (TEC) DETRE, KATHERINE. Blood pressure of children and
young adults-Oata epidemiology center.
ROlHL-1 9864-03 0003 (TEC) SCHACHTER, JOSEPH. Blood pressure of children
and young adults-Heart rate and blood pressure-Consistency in infan-
cy (human).
ROIHL-1 9869-03 (TEC) KATZ, SOLOMON H, 1 CHILDREN CENTER, 34TH ST AND
CIVIC CENTER BLVD , PHIUDELPHIA, PA. Antecedents of adolescent
hypertension (human).
ROIHL-1 9870-03 (TEC) HOHN, ARNO R, MEDICAL UNIV OF SOUTH CAROLINA 80
BARRE STREET, CHARLESTON, S C. Hypertensive progeny-Physical and
humoral precursor search.
R01HL.1 9873-03 (1MB) RICHERSON, HAL B, UNIVERSITY HOSPITALS, DEPT OF IN-
TERNAL MEDICINE, IOWA CITY, IOWA. Pulmonary responses to inhaled
antigen (rabbits, guinea pigs).
ROIHL-1 9877-02 (EDC) PRINEAS, RONALD J, UNIVERSITY OF MINNESOTA STADI-
UM GATE 27, MINNEAPOLIS, MINN. Prevention of high blood pressure
in children.
R01HL-19898-03 (SSS) HILGARTNER, MARGARET W, NEW YORK HOSP CORNELL
MEO CTR, 525 EAST 68TH STREET, NEW YORK, N Y. Desferrioxamine
therapy in thalassemia (dogs, rats, children).
ROIHl-1 9922-03 (TEC) ELLISON, ROBERT C, CHILDREN'S HOSPITAL MED CTR 300
LONGWOOD AVENUE, BOSTON, MASS. Childhood determinants of blood
pressure.
R01HL-19929-03 (TEC) BAER, PAUL E, BAYLOR COLLEGE OF MEDICINE 1200
MOURSUND AVENUE, HOUSTON, TEX. High blood pressure in the
young, prevalence and precursors (human).
ROlHL-1 9930-03 (TEC) GELBANO, HENRY, UNIVERSITY OF MIAMI, P 0 BOX
520875, MIAMI, FU. A prospective study-Blood pressure in newborn
twins.
ROIHl-19933-02 (HEM) FAIRBANKS, GRANT, WORCESTER FDN/EXP BIOLOGY
INC, 222 MAPLE AVENUE, SHREWSBURY, MASS. Membrane and red
cell dysfunction in hemolytic anemia (human).
ROIHL-1 9936-02 (NTN) HOLLOWAY, CAROLINE T, UNIVERSITY OF VIRGINIA
BIOCHEMISTRY DEPARTMENT, CHARLOTTESVILLE, VA. Unsaturated fatty
acid biosynthesis in the aorta (rats).
R01HL-19937.02 (CVA) BECKER, LEWIS C, JOHNS HOPKINS HOSPITAL, 601 NORTH
BROADWAY, BALTIMORE, MD. Vasodilators in experimental myocardial
infarction (dogs).
567
PROJECT NUMBER AND INVESTIGATOR ADDRESS
ROIHl-1 9946-03 (SSS) PIOMEUI, SERGIO. NEW YORK UNIVERSITY. »0 FIRSI
AVfNUr, NFW YORK, N Y Rrduction ol iton ovtfload in thalassemia
(childien. labbils, dogs monkpys)
ROIHl-19956-03 (TEC) KOTCHEN. JANE M, UNIVERSITY OF KENTUCKY. DEPT OF
COMMUNITY MEDICINl, LEXINGTON. KY High blood ptessute m the
young (human)
lt01Hl-l9961-03 (SSS) PEARSON. HOWARD A. YALE UNIVERSITY. 333 CEDAR
STREET. NEW HAVEN, CONN Management of hemosideiosis in thalas
semia (children, adults)
ROIHl-l 99*2-03 (TEC) HIGCINS. MILUCENT W. UNIVERSITY OF MICHIGAN. 109
OBSERVATORY STREET. ANN ARBOR. MICH High blood piessuie in
young people in Tecumseh
R01Hl-)9973-01 (BBCA) HIRKO. ROBERT J, MEMPHIS STATE UNIVERSITY. ELEC
TRICAL ENGINEERING DEPT. MEMPHIS. TENN Non invasive sickled cell
monitoi development (human)
R01HL-19974-03 (EXP) WEISS, JAY M. ROCKEFELLER UNIVERSITY. 1230 YORK
AVENUE. NEW YORK. N Y Psychologic-behavioral influences on heart
pathology (rats)
R0)HL-19975-02 (CMS) FINK, B RAYMOND, UNIVERSITY OF WASHINGTON. RN 10
B81469 HSB. SEATTLE. WASH Laryngeal biomechanics in pulmonary
therapy (primates)
ROIHl-1 9977-02 (CVB) GOLDFARB, ROY 0. ALBANY MED COLL OF UNION UNIV.
• 47 NEW SCOTUND AVENUE. ALBANY. N Y Genesis of circulatory
shock by pancreatic peptides (cats, dogs)
R01HL-I99B2-02 (BBCA) CASTEUINO, FRANCIS J, UNIVERSITY OF NOTRE DAME.
DEPARTMENT OF CHEMISTRY, NOTRE DAME. IND Blood coagulation--
Protein metal lon-lipid interactions
ROIHl-19984-02 (TEC) MATHEWS, JOHN D, UNIVERSITY OF MELBOURNE.
MEDICINE DEPARTMENT, VICTORIA. AUSTRALIA Blood pressure and im-
munogenetic factors in the young (human)
ROIHl-1 9993-02 (SGYB) ISHIMARU, AKIRA, UNIVERSITY OF WASHINGTON. 211
ELECTRICAL ENGR BLDG FTIO. SEAHLE. WASH Optical detection of
platelet aggregates (human, baboons)
ROIHL-1 9995-02 (PHY) CHAPMAN, KENT M, BROWN UNIVERSITY. BOX G.
PROVIDENCE. R I. Sensory transduction in cardiac mechanoreceptors
(cats, frogs, rats),
ROIHL-1 9996-02 (HEM) GEORGE, JAMES N, UNIVERSITY OF TEXAS. 7703 FLOYD
CURL DRIVE. SAN ANTONIO, TEX. Role of membrane proteins in
platelet function (human, rabbits).
ROlHl-1 9997-02 (CVB) CHAPNICK, BARRY M, TUUNE UNIVERSITY. 1430 TU
LANE AVENUE. NEW ORLEANS. LA Prostaglandin precursors and in-
testinal vasculature (cats, rabbits).
R01H1-20000-03 (SSS) NATHAN, DAVID G, CHILDREN'S HOSPITAL. 300 LONG-
WOOD AVENUE. BOSTON. MASS, Iron overload in homozygous beta
thalassemia (human).
ROIHl-20002-03 (SSS) MILLER, MICHAEL E, HARBOR GENERAL HOSPITAL, 1000
CARSON STREET, BLDG E-6. TORRANCE. CALIF. Pulmonary complica-
tions of viral infections (children).
R0IHL-2000S-03 (TEC) PHILLIPS, ROLAND I, LOMA LINDA UNIVERSITY, SCHOOL
OF HEALTH. LOMA LINDA, CALIF. Factors in blood pressure levels of
children.
ROT Hl-2001 4-02 (HEM) CHEN, JAMES P, UNIVERSITY OF TENNESSEE. 1924
ALCOA HIGHWAY. KNOXVILLE. TENN. Radioimmunoassay of hyper and
hypocoagulable states (rabbits).
ROIHL-20016-03 (SSS) CERAMI, ANTHONY, ROCKEFELLER UNIVERSITY, 1230
YORK AVENUE, NEW YORK, N Y Chelator development for thalassemia
(human, mice. rats. dogs, monkeys).
ROIHl-20024-03 (SSS) HILLER, f CHARLES, UNIVERSITY OF ARKANSAS. 4301
WEST MARKHAM STREET. LITTLE ROCK, ARK, Therapeutic aerosols-
Characteristics and retention (human, dogs).
R01HL-20034-03 (TEC) GRIM, CLARENCE E, INDIANA UNIVERSITY. 1100 WEST
MICHIGAN STREET, INDIANAPOLIS, IND. Hypertension -Psychophysiologic
and genetic precursors (human).
ROIHl-20037-02 (SGYB) BERNHARD, WILLIAM F, CHILDREN S HOSPITAL MED
CTR. 300 LONGWOOD AVENUE. BOSTON. MASS, Lett ventricular-aortic
bypass and composite prosthesis (sheep, swine, cattle).
ROIHL-20054-02 (CVB) GIMBRONE, MICHAEL A, JR, PETER BENT BRIGHAM
HOSPITAL, 721 HUNTINGTON AVENUE. BOSTON. MASS. Cultured blood
vessel cells -Pathophysiology (human, animals).
R01HL-20061-02 (MET) GWYNNE, JOHN T, UNIVERSITY Of NORTH CAROLINA,
DEPARTMENT OF MEDICINE, CHAPEL HILL, N C. Serum lipoproteins and
cell cholesterol metabolism (rats, human).
R01HL-20063-03 (SSS) KITE, JOSEPH H, JR, S U N Y - AT BUFFALO, 3435 MAIN
STREET. BUFFALO. N Y. Pathogenesis of pulmonary mycoplasma infec-
tions (guinea pigs. mice).
ROIHL-20070-02 (SSS) CASKEY, CHARLES T, BAYLOR COLLEGE OF MEDICINE.
1200 MOURSUND AVENUE. HOUSTON. TEX. Alpha-1-antitr^psin deficien-
cy (human, hamsters).
ROIHl-20073-02 (SGYB) PREDECKI, PAUL K, UNIVERSITY OF DENVER. SPACE
SCIENCES BUILDING. DENVER. COLO. Blood compatible materials by
fluid perfusion (human, dogs).
ROIHl-20074-02 (HEM) NIEHAUS, WALTER G, JR, VA POLYTECH INST & ST
UNIV. DEPT BIOCHEMISTRY & NUTRITION . BLACKSBURG. VA. Structure
and function of amidinated human hemoglobin.
ROIHL-20077-02 (SSS) ZOLL, PAUL M, BETH ISRAEL HOSPITAL, 330 BROOKLINE
AVENUE, BOSTON. MASS. External cardiac stimulation with microwave
radiation (dogs).
R01HL-20079-02 (SGYB) SALZMAN, EDWIN W, MASSAVCHUSEHS INST OF
TECH. BUILDING 168 ROOM 522, CAMBRIDGE. MASS. Thromboresistant
material.
ROIHl-20079-02 0001 (SGYB) MERRILL, EDWARD W. Thromboresistant materi-
al-Active and passive thromboresistant surfaces.
ROIHl-20079-02 0002 (SGYB) SALZMAN, EDWIN W. Thromboresistant materi
al"Thromboresistant materials (sheep).
ROIHL-20079-02 0003 (SGYB) WAUGH, DAVID F. Thromboresistant material--
Blood surface interactions (human, cattle).
ROIHL-20080-02 (SGYB) BUCKBERG, GERALD D, UNIVERSITY OF CALIFORNIA.
DIVISION OF THORACIC SURGERY. LOS ANGELES. CALIF. Surgically in-
duced myocardial edema (dogs).
ROIHL-20086-02 (SGYA) WITTE, MARLYS H, ARIZONA MEDICAL CENTER. 1501
NORTH CAMPBELL AVENUE. TUCSON. ARIZ. Circulatory control of
splenic function (rats).
ROIHl-20087-02 (CVA) HUXTABLE, RYAN J, UNIVERSITY OF ARIZONA. DEPART-
MENT OF PHARMACOLOGY, TUCSON. ARIZ. Developmental processes in
pulmonary hypertension (rats).
R0)HL-2009202 (HEM) MARTINEZ, JOSi, IIIIIHSON MEDICAL COUCGE. IOI&
WAINUI SIRfM. PHIIADFIPHIA. PA SIruclurtI (nd bioloiical propac
lies ol librinogen (human, rabbits)
R0IHI-2009S-03 (SSS) JOHNSON, ROBERT I, UNIVERSIIY OF CINCINNAIL 731
BETHESDA AVFNUI, CINCINNAII, OHIO Role of lymphokinei and mono
cytes in lung fibrosis (human, guinea pigs, rats)
R01HL.20I04.03 (SSS) BOROS, OOV L, WAYNE STATE UNIVERSITY. 540 EAST CAN
FIELD. DETROIT. MICH Pulmonary granulomatous inflammations
(mice)
ROlML.20105-02 (SSS) SCHERER, PETER W, UNIVERSIIY OF PENNSYLVANIA. 383
lOWNE BLDG. 03. PHILADELPHIA. PA Deposition of hygroscopic
aerosols in bronchi (dogs, human, models)
ROIHL-20106-02 (SSS) COHEN, ISAAC, NORTHWESTERN UNIVERSITY. BIOCHEM &
MOLECULAR BIO DEPT. EVANSTON. ILL Coupling of pfalelel contractile
proteins to fibrin (human)
R01HL-201 10-02 (SSS) DURNEY. CARL H. UNIVERSITY OF UTAH. DEPARTMENT OF
BIOENGINEERING. SALT LAKE CITY. UTAH Microwave methods of lung
water measurement (dogs, phantom models)
ROIHl-201 14-02 (HEM) KANG, ANDREW H, VETERANS. 1030 JEFFERSON
AVENUE. MEMPHIS. TENN Collagen platelet interaction and human
aorta collagen (human)
ROIHl-201 16-01 (BIO) TAYLOR, KENNETH B, UNIVERSITY OF AUBAMA. UNIVER
SITY STATION. BIRMINGHAM, AU Heart lactate dehydrogenase The
complex with NADH (pig)
ROIHL-201 22-02 (CVA) SANT'AMBROGIO, GIUSEPPE, UNIVERSITY OF TEXAS
MEDICAL BR, DEPT OF PHYSIOLOGY & BIOPHYS, GALVESTON, TEX
Operational mechanisms of airway receptors (dogs, pigs)
ROIHL-201 24-02 (EDC) LAUER, RONALD M, UNIVERSITY HOSPITALS. DIV OF
PEDIATRIC CARDIOLOGY, IOWA CITY, IOWA Coronary risk factors
(human),
ROIHl-201 25-02 (ALY) NICHOLS, WILLIAM K, UNIVERSITY OF UTAH. DEPT OF
BIOPHARMACEUTICAL SCIS. SALT LAKE CITY. UTAH Cyclic nucleotides
and alveolar macrophage activation (rabbits)
ROIHL-201 32-03 (SSS) ROSENQUIST, GLENN C, UNIVERSITY OF NEBRASKA.
42ND & DEWEY AVENUE, OMAHA. NEBR. Histogenesis and biochemis-
try of embryonic lung (birds)
ROIHL-201 40-02 (HEM) MARCHESI, SALLY I, YALE UNIVERSITY. 333 CEOAR
STREET, NEW HAVEN, CONN, Glycoproteins of platelet membrane and
platelet function (human),
R01HL-20141-02 (HEM) HARRIS, DANIEL C, UNIVERSITY OF CALIFORNIA. DEPART-
MENT OF CHEMISTRY, DAVIS, CALIF Biochemical approaches to
management of iron overload (human, sheep, dogs).
R01HL-20142-02 (HEM) JONES, RICHARD T, UNIVERSITY OF OREGON. 3181 S W
SAM JACKSON PARK RD. PORTLAND. OREG. Functional studies of ab-
normal human hcmoglobins.
R01HL-201 43-02 (SGYA) NORWOOD, WILLIAM I, CHILDREN S HOSPITAL MED
CTR, 300 LONGWOOD AVENUE, BOSTON. MASS. Hypothermic circulatory
arrest -Cerebral vascular change (dogs).
ROIHl-201 53-02 (PHY) HOLLANDER, PHILIP B, OHIO STATE UNIVERSITY, 1645
NEIL AVENUE, COLUMBUS, OHIO. Intracellular pH and myocardial elec-
tropharmacology (dogs, guinea pigs).
ROIHL-201 59-03 (TEC) WARD, RICHARD H, UNIVERSITY OF WASHINGTON. CHILD
DEV & MENT RETD CTR RC 8, SEATTLE. WASH. Genetic epidemiology
of precursors of hypertension (human).
ROIHL-201 61 -02 (SSS) HISKEY, RICHARD G, UNIVERSITY OF NORTH CAROLINA.
CHEMISTRY DEPARTMENT. CHAPEL HILL. N C. Role of gamma-carbox-
yglutamic acid in blood coagulation (human, cattle).
ROIHL-201 63-02 (SGYA) BAHLER, ALAN S, MOUNT SINAI SCHOOL. lOOTH STREET
AND 5TH AVENUE, NEW YORK. N Y, Competitive coronary flow in na-
tive and graft vessels (dog).
ROIHL-201 70-02 (SGYA) DICKERSON, JOSEPH D, UNIVERSITY OF VERMONT.
COLLEGE OF MEDICINE. BURLINGTON, VERMONT. Pulmonary infection
in splenectomized animals (mice).
ROIHL-201 76-02 (GMB) RAPP, JOHN P, MEDICAL COLLEGE OF OHIO. C S 10008,
TOLEDO. OHIO. Biochemistry and genetics of salt hypertension (rats).
ROIHL-201 77-02 (CVB) JOHNSON, GEORGE, JR, UNIVERSITY OF NORTH
CAROLINA. DEPARTMENT OF SURGERY. CHAPEL HILL. N C. Effects of
erythrocyte deformability on tissue perfusion (rats).
ROlHL-201 79-02 (EDC) KULLER, LEWIS H, UNIVERSITY OF PITTSBURGH. A-435
CRABTREE HALL, PITTSBURGH, PA. Epidemiology of sudden cardiac
death among women.
ROIHL-201 83-02 (CVB) LUMB, WILLIAM V, COLORADO STATE UNIV SURGICAL L,
FT COLLINS, COLO. Portacaval shunt as treatment for hyperlipemia
(pigs).
ROIHL-201 84-02 (CVA) AVNER, BARRY P, UNIVERSITY OF NEW MEXICO. 915
STANFORD, N E. ALBUQUERQUE. N MEX. Desensitization of tracheal
muscle to isoproterenol (rats, rabbits).
ROIHL-201 87-01 (AFY) HARTLEY, lOREN H, BETH ISRAEL HOSPITAL. 330
BROOKLINE AVENUE, BOSTON. MASS. Evaluation of exercise cardiac
rehabilitation program (40-55 year old men).
ROIHL-201 89-01 (PTHA) OVERTURE, MERRILL I, UNIVERSITY OF TEXAS. POST OF
FICE BOX 20708, HOUSTON, TEX. Effects of renin on atherogenesis
(rabbits).
ROIHL-201 90-02 (CVB) BLOOR, COLIN M, UNIV OF CALIFORNIA. SAN DIEGO. SCH
OF MED. M012. LA JOLLA. CALIF. Pathogenesis of cardiac hypertrophy
(dogs).
ROlHL-201 92-02 (CVA) VERDUGO, PEDRO, UNIVERSITY OF WASHINGTON. HEALTH
SCIENCES BLDG RF-52. SEATTLE. WASH. Ciliary activity of the lung
studied by laser scattering.
ROIHL-201 94-01 (PHRA) FREED, CURT R, UNIVERSITY OF COLORADO. 4200 EAST
NINTH AVENUE, DENVER, COLO. Brain catecholamines in control of
blood pressure (rats).
ROIHL-201 96-02 (CVA) DISALVO, JOSEPH, UNIVERSITY OF CINCINNATI. 231
BETHESDA AVENUE. CINCINNATI. OHIO. Regulation of coronary arterial
smooth muscle.
ROIHL-201 97-02 (PTHA) GOSPODAROWICZ, DENIS J, UNIVERSITY OF CALIFOR-
NIA. 3RD & PARNASSUS AVENUES, SAN FRANCISCO, CALIF. Main-
tenance and repair of vascular endothelium (human, animals).
ROIHl-201 99-02 (PTHA) MAROKO, PETER R, PETER BENT BRIGHAM HOSPITAL,
721 HUNTINGTON AVENUE, BOSTON. MASS. Drug-induced alterations in
infarct size in the rat.
ROlHL-20201-01 (CVB) MEYER, WALTER J, III, UNIVERSITY OF TEXAS. DEPT OF
PEDIATRICS. GALVESTON. TEX. Hypertension and vascular steroid
receptors (rats).
PROJECT NUMBER AND INVESTIGATOR ADDRESS
568
R0)Hl-20206-02 (CVB) MAIIK, KAFAIT U, UNIVERSITY OF TENNESSEE, 800 ROIHL-20350
MADISON AVENUE, MEMPHIS. TENN. Carbohydrales-nucleotldes and
adrenergic intcactions (rabbits, cats, rats).
R0IHL-202n-02 (CVB) KOCSIS, JAMES J, THOMAS JEFFERSON UNIVERSITY, 1020 R01HL-2035l-(
LOCUST STREET PHILADELPHIA, PA. Role of taurine m the heart
(dogs, rats, mice).
R01HL-202 18-02 (HEM) FIETCHER, ANTHONY P, WASHINGTON UNIVERSITY, 660 R01HL-20352
SOUTH EUCLID, ST LOUIS, MO. Fibrinogen catabolism and intravascu-
lar coagulation (human)
R01HL-202 19-02 (SGYA) CRAVALHO, ERNEST G, MASSACHUSETTS INST OF R01HL-20354
TECH, BLDG 16-522, 77 MASS AVE, CAMBRIDGE, MASS. Cryopreserva-
tion of the isolated heart (rats).
R01HL-20220-03 (SSS) HUGH, TONY E, SCRIPPS CLINIC & RESEARCH EON, 476 R01HL-20356-I
PROSPECT STREET, U JOLLA, CALIF. Anaphylatoxins as inflammatory
and chemotactic agents (guinea pig, rabbit, human).
R01HL-20226-02 (SGYA) WECHSLER. ANDREW S, DUKE UNIVERSITY, BOX 3174, R01HL-20364
DURHAM, N C. Cardiac bypass and coronary collateral physiology
(dogs).
R01HL-20230-02 (PHY) EISENBERG, ROBERT S, ST LUKES MEDICAL CENTER, R01HL-2036S-I
CHICAGO, ILL, PHD. Analysis of the action potential of cardiac muscle
(sheep).
R01HL-20238-02 (CVB) SCHEINMAN, MEIVIN M, SAN FRANCISCO GENERAL R01HL-20366
HOSPITAL, 1001 POTRERO, SAN FRANCISCO, CALIF. Prospective bundle
branch block study (human).
ROIHl-20241-02 (BBCA) ZARKOWSKY, HAROLD S. WASHINGTON UNIVERSITY, R01HL-20369
500 SOUTH KINGSHIGHWAY, ST LOUIS, MO. Shear and area moduli for
abnormal red cell membranes (human).
R01HL-20244-02 (TEC) HARDY, ROBERT J, 1100 HOLCOMBE BLVO ROOM 1114, R01HL-20371-I
HOUSTON, TEXAS, he impact of hypertension information.
R01HL-2024S-01 (TEC) APOSTOUDES, ARISTIDE Y, UNIVERSITY OF MARYLAND,
31 SOUTt; GREENE STREET, BALTIMORE, MD. The impact of hyperten- ROIHL-20373-i
sion information.
R01HL-20247-01 (TEC) KRAUS, JESS f, UNIVERSITY OF CALIFORNIA, DEPARTMENT
OF COMMUNITY HLTH. DAVIS, CALIF. The impact of hypertension infor- ROIHL-20374-i
mation.
R01HI-20248-01 (TEC) OBERMAN. ALBERT, UNIVERSITY OF AUBAMA, BOX 39
OBSB UNIVERSITY STAT, BIRMINGTON, ALA. The impact of hypertension R01HL-20381-I
information
R01HL-202S1-02 (SGYB) KIM, SUNG-WAN, UNIVERSITY OF UTAH, SKAGGS HALL,
SALT LAKE CITY, UTAH. A novel approach to nonthrombogenic polymer ROIHL-20384-i
surfaces (sheep, cattle).
R01HL-20253-02 (AFY) BARNARD, R JAMES, UNIVERSITY OF CALIFORNIA. 10833
LE CONTE AVENUE, LOS ANGELES, CALIF Effects of exercise on the R01HL-20388
heart and its blood supply (dogs).
R01HL-202S4-02 (PHY) KRASNE, SALLY J, UNIVERSITY OF CALIFORNIA, PHYSIOLO-
GY DEPARTMENT, LOS ANGELES, CALIF. Probes of heart and nerve R01HL-2039I
membranes -Fluorescent dyes.
R01HL-20262-02 (PHRA) FORTES, P A, UNIV OF CALIFORNIA, SAN DIEGO, BIOLOGY
DEPARTMENT, LA JOLLA, CALIF. Cardiac glycosides and the ROIHL-20393-i
mechanisid of the sodium-potassium pump.
R01HL-20273-02 (CVB) SCHER, ALLEN M, UNIVERSITY OF WASHINGTON, SCHOOL
OF MEDICINE, SEAHLE, WASH. Cardiac fiber direction and the QRS R01HL-20394
complex (riogs).
ROIHL-20274-02 (RAD) CHESLER, DAVID A, MASSACHUSETTS GENERAL
HOSPITAL, PHYSICS RESEARCH UBORATORY. BOSTON, MASS. Gated ROIHL-20397-i
imaging with the MGH x-ray camera.
R01HL-20278-02 (GMB) POISNER, ALAN M, UNIVERSITY OF KANSAS, 39TH
STREET AT RAINBOW BLVO, KANSAS CITY, KANS. Cellular mechanisms R01HL-20399
of renin secretion (rats).
R01HL-20283-02 (CVB) SPATH, JAMES A, JR, JEFFERSON MEDICAL COLLEGE,
1020 LOCUST STREET, PHIUDELPHIA, PA. Maintenance of cellular in- ROIHL-20400
tegrity in ischemic hearts (cats).
R01HL-20286-02 (CVA) JONES, CARL E, TEXAS A & M UNIVERSITY, COLLEGE OF
MEDICINE, COLLEGE STATION, TEX. Interventions to improve cardiac ROIHL-20401-i
function in ischemia (dogs).
R01HL-20300-02 (MBY) SUNG, MICHAEL T, SOUTHERN ILLINOIS UNIVERSITY, DE-
PARTMENT OF CHEMISTRY, CARBONDALR, ILL. Histone H5 and avian ROIHL-20408-i
erythropoiesis (chickens, rabbits).
ROIHl-20301-02 (GEN) YOSHIDA, AKIRA Y, CITY OF HOPE NATIONAL MED CTR,
1500 LAST DUARTE ROAD, DUARTE, CALIF. Genetics of glycosyltrans- R01HL-2041 l-i
ferases in human blood.
R01HL-20303-03 (HEM) LANGE, YVONNE, UNIVERSITY HOSPITAL, 75 E NEWTON
STREET, BOSTON, MASS. Cholesterol distribution in erythrocyte mem- ROIHl-20418.
brane (human, animals).
R01HL-20308-02 (MET) W/ENGER, JANE I, MILTON S HERSHEY MEDICAL CTR, DE-
PARTMENT OF PHYSIOLOGY, HERSHEY, PA. Regulation of myocardial R01HL-20426.
acylcarnitine transport (rats).
R01HL-203 13-02 (SGYA) RODVIEN, ROBERT, INSTITUTE OF MEDICAL SCIENCES,
POST OFFICE BOX 7999, SAN FRANCISCO, CALIF. Surface-induced R01HL.20428.
thrombosis-Modification of albumin variants (human, goat).
R01HL-203 14-02 (BM) BJORNSON, ANN B, UNIVERSITY OF CINCINNATI, 231
BETHESDA AVENUE, CINCINNATI, OHIO. Host defense against S pheu- ROIHl-20429.
moniae in sickle cell disease (human).
ROIHl-20317-02 (HEM) MC COY, LOWELL E, WAYNE STATE UNIVERSITY, 540
EAST CANFIELD, DETROIT, MICH. Procoagulant lipoproteins -Biochemis- R01HL-20439-
try and bioactiuity (goats, rabbits),
ROIHL-203 19-02 (BBCA) HERMANS, JAN, UNIVERSITY OF NORTH CAROLINA, DE-
PARTMENT OF BIOCHEMISTRY, CHAPEL HILL, N C. Assembly, structure ROIHL-20446-i
and interactions of fibrin (human),
R01HL-20328-01 (CVA) KATONA, PETER G, CASE WESTERN RESERVE UNIV, DEPT
OF BIOMEDICAL ENGINEERING, CLEVELAND, OHIO. Noninvasive assess- ROlHL-20447-i
ment of autonomic cardiac control (dogs).
R01HL-20337-02 (NED) HATHAWAY, WILLIAM E, UNIVERSITY OF COLORADO,
4200 E NINTH AVENUE, DENVER, COLO. Thromboembolic diseases R01HL-204S5-I
(human).
ROIHL-20339-02 (PHRA) LEFKOWIT2, ROBERT J, DUKE UNIVERSITY, MEDICAL
SCIENCE BUILDING 16, DURHAM, N C. Vascular alpha-adrenergic ROIHL-20460-i
receptor molecular properties.
R01HL-20344-02 (CVA) RANNELS, D EUGENE, JR, PENNSYLVANIA STATE
UNIVERSITY, DEPARTMENT OF PHYSIOLOGY, HERSHEY, PA. Regulation R01HL-20464
of protein turnover In lung tissue (rats).
ROIHl-20347-02 (AFY) ULTMAN, JAMES S, PENNSYLVANIA STATE UNIVERSITY, R01HL-20471
106 FENSKE UBORATORY, UNIVERSITY PARK, PA. Bolus-response mea-
surement of lung function (human).
02 (BBCB) CRAVEN, BRYAN M, UNIVERSITY OF PIHSBURGH, DE-
PARTMENT OF CRYSTALLOGRAPHY , PITTSBURGH, PA. Crystal structure
of lipids -Cholesterol.
•02 (AFY) CLARK, JUSTIN S, PRIMARY CHILFRENS MED CENTER,
320 TWELFTH AVENUE, SALT LAKE CITY, UTAH. A self-calibrating in
vivo blood gas monitor (dogs, infants).
02 (CVA) FANBURG, BARRY L, NEW ENGLAND MEDICAL CTR HOSP,
171 HARRISON AVENUE, BOSTON, MASS. Defenses of lung cells
against oxygen toxicity (human, animals).
■02 (CVA) ZICK, GREGORY L, UNIVERSITY OF WASHINGTON, DEPT
OF ELECTRICAL ENGR FTIO , SEAmE, WASH. Direct determination of
oxygen tension in the clinical environment (human, dogs) .
02 (SGYA) PIERCE, WILLIAM S, PENNSYLVANIA STATE UNIVERSITY.
500 UNIVERSITY DRIVE, HERSHEY, PA. Development and evaluation of
an artificial heart (calves).
-01 (SSS) HERD, JAMES A, HARVARD MEDICAL SCHOOL, 25 SHAT-
TUCK STREET, BOSTON, MASS. Episodic hypertension associated with
human behavior (air traffic controllers).
■03 (PHY) GUNN, ROBERT B, UNIVERSITY OF CHICAGO, 951 EAST
58TH STREET. CHICAGO, ILL. Molecular mechanisms of anion trans-
port.
03 (CVA) MASSARO, DONALD J, UNIVERSITY OF MIAMI, P 0 BOX
520875 BISCAYNE ANNEX , MIAMI, FLA. Protein turnover and amino
acid transport by lung (rats).
03 (ALC) SARDESAI, VISHWANATH M, WAYNE STATE UNIVERSITY.
540 E CANFIELD, DETROIT, MICH. The effect of alcohol on the heart
(rats).
02 (CVA) GREEN, JERRY F, UNIVERSITY OF CALIFORNIA, DEPT OF
HUMAN PHYSIOLOGY, DAVIS, CALIF. Intravascular redistribution of
blood volume (dogs).
02 (AFY) HARRISON, WALTER K, VETERANS ADMINISTRATION
HOSP, 3350 U JOLLA VILLAGE DRIVE, SAN DIEGO, CALIF. Cardiovascu-
lar aging in young men and women.
03 (TEC) HARRISON, WALTER K, VETERANS ADMINISTRATION
HOSP, 3350 LA JOLU VILLAGE DRIVE, SAN DIEGO, CALIF. Myocardial
function -Risk factors and future CHD (human).
■03 (SRC) STRANONESS, DONALD E, JR, UNIVERSITY OF WASHING-
TON, DEPARTMENT OF SURGERY, RF-25, SEATTLE, WASH. Long-term
study of diabetic vascular disease (human).
09 (NEUB) SANTISTEBAN, GEORGE A, PACIFIC NORTHWEST
RESEARCH FDN, 1102 COLUMBIA STREET, SEAHLE, WASH. Social
stimulation, RNA and cardiovascular disease (animals).
03 (SRC) MORGAN, HOWARD E, MILTON S HERSHEY MEDICAL
CTR, PHYSIOLOGY DEPARTMENT, HERSHEY, PA. Regulation of protein
turnover in diabetic heart (rat).
03 (SRC) FISHER, WALDO R, UNIVERSITY OF FLORIDA, BOX J-226
JHMHC, GAINESVILLE, FLA. Polydisperse LDL-Structure. metabolism
and function (human).
03 (SRC) KOLER, ROBERT D, UNIVERSITY OF OREGON. 3181 S W
SAM JACKSON PARK RD, PORTLAND, OREG. Postsynthetic modifications
of hemoglobin in diabetics (human).
03 (SRC) PINCKARD, ROBERT N, UNIVERSITY OF TEXAS, 77C3
FLOYD CURL DRIVE, SAN ANTONIO, TEX. Complement activation by
heart subcellular membranes (human, dog).
03 (SRC) REAVEN, GERALD M, STANFORD UNIVERSITY, SCHOOL OF
MEDICINE, STANFORD. CALIF VLDL-TG metabolism in diabetes mellitis
(human, rat).
03 (SRC) SPARKS, HARVEY V, UNIVERSITY OF MICHIGAN.
PHYSIOLOGY DEPARTMENT, ANN ARBOR, MICH. Vascular control in ex-
perimental diabetes mellitus (dog).
03 (PTHA) GROVER-JOHNSON, NICOLA M, NEW YORK UNIVER-
SITY, 550 FIRST AVENUE, NEW YORK, N Y. Diabetic neuropathy and
peripheral vascular diseases (human, hamsters).
03 (SRC) DOWNING, S EVANS, YALE UNIVERSITY, 333 CEDAR
STREET, NEW HAVEN, CONN. Relationship of insulin to catechol car-
diomyopathy (rabbit, pig).
03 (SRC) COSTILL, DAVID L, BALL STATE UNIVERSITY, HUMAN PER-
FORMANCE LABORATORY, MUNCIE, INO. Hyperlipidemla in diabetics
during muscular training (human).
03 (SRC) HUNTLEY, THOMAS E, UNIVERSITY OF MINNESOTA. 2205
EAST 5TH STREET, DULUTH, MINN. Platelet fatty acid metabolism in
diabetes (rat, rabbit, guinea pig).
03 (SRC) HSIA, SUNG L, UNIVERSITY OF MIAMI, P 0 BOX 520875.
BISCAYNE ANNEX, MIAMI, FLA. Serum cholesterol binding reserve in
diabetes (human).
03 (SRC) SONNENBLICK, EDMUND H, ALBERT EINSTEIN COLLEGE
OF MED, 1300 MORRIS PARK AVENUE, BRONX, N Y. Myocardial func-
tion in diabetes mellitus (dog, rat).
03 (SRC) SCOTT, RALPH C, UNIVERSITY OF CINCINNATI, 231
BETHESDA AVENUE, CINCINNATI, OHIO. The juvenile diabetic heart
(human).
03 (SRC) REEVES, JOHN T, UNIVERSITY OF COLORADO, 4200 EAST
NINTH AVENUE, DENVER, COLO. Study of effects of diabetes reactivity
(miniature pigs, rats).
02 (SRC) STEINSLAND, ODD S, UNIVERSITY OF TEXAS, PHAR
MACOLOGY & TOXICOLOGY DEPT, GALVESTON. TEX. Effects of insulin
on neurovascular transmission (human, rats, rabbits, hamsters).
02 (SRC) GIACHETTI, ANTONIO, UNIVERSITY OF TEXAS, 5323
HARRY HINES BLVD, DALLAS, TEX. Autonomic neuropathy in diabetic
mice (also rats).
■03 (SRC) Dl FERRANTE, NICOLA M, BAYLOR COLLEGE OF
MEDICINE. 1200 MOURSUND AVENUE, HOUSTON, TEX. Connective tis-
sue and diabetic vascular disease (human).
03 (SRC) PATZ. ARNALL, JOHNS HOPKINS MEDICAL INST, 601
NORTH BROADWAY, BALTIMORE, MD. Role of systemic hypertension on
diabetic retinopathy (human).
03 (SRC) HOLLIS, THEODORE M, PENNSYLVANIA STATE UNIVERSI
TY, 416 LIFE SCIENCE I, UNIVERSITY PARK, PA. Aortic histamine
synthesis in diabetes (rat).
01 (BBCB) LEAVIS, PAUL C, 20 STANIFORD STREET, BOSTON. MASS.
Regulation of cardiac and skeletal muscle contraction (mammals).
03 (SRC) GILBERT, DAVID B, DUKE UNIVERSITY. DEPARTMENT OF
MEDICINE. DURHAM. N C. Atherosclerosis and diabetes mellitus
(human).
1
S69
PROJECT NUMBER AND INVESTIGATOR ADDRESS
ROlMl-20476-03 (SRC) MIUIH, THOMAS B, JR. UNIVERSITY OF MASSACHUSEIIS.
55 UKE AVENUE NORIH. WORCESTER. MASS Ell«cls of diabsles on
cardiac perlotmance (lat)
ROIHl-30483-03 (SRC) PAIUMBO, PASQUAIE J. MAYO FOUNDATION. 200 FIRST
STREET SOUIHWESI, ROCHFSTfR. MINN Sterol balance and
cholesterol absorption in diabetics (human)
ROIHl-20484.03 (SRC) NtElY. JAMES R, MILTON S HERSHEY MED CENTER. DE
PARTMENT OT PHYSIOLOGY. HERSHEY. PA Ellects of diabetes on car
diac tunclion and metabolism dais)
R0IHI-204BB-03 (SRC) SAUDEK, CHRISTOPHER D. CORNELL UNIVERSITY. 1300
YORK AVENUE. NEW YORK. N Y Cholesterol metabolism in diabetic
man
R01HH05O0-02 (PTHA) MEEIAN. EUAS, UNIVERSITY OF ARIZONA. OEPT OF
PHARMACOLOGY & PATH, TUCSON. ARIZ Diabetic human brain
microvascular basement membrane (human)
R01H1.20S0B-03 (SRC) OSTRANDER, LEON O. JR, UNIVERSITY OF MICHIGAN.
109 OBSERVATORY STREET. ANN ARBOR. MICH Diabetes, hyper
glycemia and cardiovascular disease (human)
R0IHl-20St7-03 (SRC) VANOERIAAN, WILIARD P, SCRIPPS CLINIC &
RESEARCH FDN, 10666 N TORREY PINES ROAD. LA JOLLA. CALIF
Diabetes, somatotropin, factor VIII and atherosclerosis (human,
animal)
ROIHl-20520-03 (SRC) CERAMI, ANTHONY, ROCKEFELLER UNIVERSITY. 1230
YORK AVENUE. NEW YORK. N Y Protein modification- The key to
diabetic sequelae {human, animal).
R01HL-20522-03 (SRC) PAIUMBO. PASQUAIE J, MAYO FOUNDATION. 200 FIRST
STREET SOUTHWEST. ROCHESTER. MINN. Peripheral arlerial disease in
the diabetic (human)
R01HL-20S33-09 (AIY) AYOUB. EllA M, UNIVERSITY OF FLORIDA. POST OFFICE
BOX 739. GAINESVILLE. FLA Pathogenesis of rheumatic fever (human.
rabbits).
R01HL-2053S-02 (SRC) O'SUUIVAN, JOHN B, DIABETES AND ARTHRITIS UNIT.
408 ATUNTIC AVENUE RM 815. BOSTON. MASS Cardiovascular dis-
ease and evolving diabetes mcllitus (human),
R01HL-20539-03 (SRC) GABBAY, KENNETH H, CHILDREN'S HOSPITAL MED CTR.
300 LONGWOOD AVENUE. BOSTON. MASS. Blood glucose, hemoglobin
Ale. and diabetic vascular disease (human).
ROIHl-20542-03 (CVB) PEGRAM, BARBARA L, ALTON OSCHSNER MED FDN.
1516 JEFFERSON HIGHWAY. NEW ORLEANS. LA, Regional hemodynam-
ics in spontaneous hypertension (rats),
R0IHI-20S44-02 (BIO) OLSON, MERLE S, UNIVERSITY OF TEXAS. 7703 FLOYD
CURL DRIVE. SAN ANTONIO. TEX, Integrated regulation of myocardial
energy metabolism (rats, guinea pigs).
R01HL-20S46-02 (PBC) SANOBERG, LAWRENCE B, UNIVERSITY OF UTAH. COL
LEGE OF MEDICINE. SALT LAKE CITY. UTAH, Chemical analysis of
human arterial elastin,
R01HI-20S47-02 (PBC) GLEW, ROBERT H, UNIVERSITY OF PIHSBURGH. DEPART-
MENT OF BIOCHEMISTRY. PITTSBURGH. PA, Glycoproteins in pulmonam
alveolar proteinosis (human)
R01HL-20548-02 (PTHA) El-BERMANI, AL-WAIID I, TURS UNIVERSITY. 136
HARRISON AVENUE. BOSTON. MASS Innervation of the lung (rats,
monkeys).
P01HL-205S2-02 (HEPA) BRAUNWALD, EUGENE, 721 HUNTINGTON AVENUE.
BOSTON. MASS. The development and regression of cardiac hyper-
trophy.
P0IHL-20S52-02 0001 (HEPA) BRAUNWALD, EUGENE. The development and
regression of cardiac hypertrophy-Biochemical events in cardiac
hypertrophy (rats),
PCI HL-20552-02 0002 (HEPA) BRAUNWALD, EUGENE. The development and
regression of cardiac hypertrophy -Effect of treatment on the hypertro-
phied left ventricle (rats),
P01HL-205S2-02 0003 (HEPA) BING, OSCAR H L. The development and regres-
sion of cardiac hypertrophy-Muscle mechanics of the hypcrtrophied
left ventricle (rats),
P01HI-20S52-02 0004 (HEPA) VAINER, STEPHEN F. The development and
regression of cardiac hypertrophy-Ventricular function in experimen-
tally induced hypertrophy (hogs, sheep, baboons),
P0IHL-205S2-02 0010 (HEPA) INGWALL, JOANNE S. The development and
regression of cardiac hypertrophy-Energy metabolism in the hypcrtro-
phied heart animals,
P01 HL-20552-02 9001 (HEPA) COTRAN, RAMZI. The development and regres-
sion of cardiac hypertrophy-Core A -Pathology,
P01 HL-20552-02 9002 (HEPA) MIRSKY, ISREAL. The development and regression
of cardiac hypertrophy-Core B-Biomathematics,
P01HL-20S52-02 9003 (HEPA) TAEGTMEYER, HEINRICH. The development and
regression of cardiac hypertrophy-Core D -Amino acids analysis,
R01HL-20SS4-02 (SGYB) SIMON, MORRIS, BETH ISRAEL HOSPITAL, 330
BROOKUNE AVENUE. BOSTON. MASS. Memory-alloy-filters for venous
emboli (dogs),
R01HL-20SS8-02 (PHY) COHEN, IRA S, S U N Y AT STONY BROOK. PHYSIOLOGY
& BIOPHYSICS DEPT. STONY BROOK. N Y, Cardiac electrophysiology-
Effects of ions and drugs,
R01HL-20563-02 (CVB) WIEDEMAN, MARY P, TEMPLE UNIVERSITY. 3420 NORTH
BROAD STREET. PHILADELPHIA. PA, Restoring microcirculation after
platelet aggregation,
R01HL-20564-02 (CVA) FRONEK, KITTY, UNIV OF CALIFORNIA. SAN DIEGO. AMES-
BIOENGINEERING. M-005. U JOLU. CALIF. Pathogenesis of peripheral
arterial disease (rats, rabbits),
ROIHl-20566-02 (CVA) RHOADES, RODNEY A, INDIANA UNIVERSITY, 1100 WEST
MICHIGAN STREET. INDIANAPOLIS. IND, Lactate metabolism in the lung
(rats),
ROIHl-20568-03 (CVA) LAI, YIH-LOONG, VIRGINIA MASON RESEARCH CENTER,
1000 SENECA STREET. SEATTLE. WASH, Respiration during prolonged
hypercapnia (rats),
ROIHl-20572-02 (CVB) FROHLICH, EDWARD D, ALTON OCHSNER MEDICAL FDN.
1516 JEFFERSON HIGHWAY. NEW ORLEANS, LA. Hemodynamic relations
to metabolism in hypertension,
R01HI-20572-02 0001 (CVB) FROHLICH, EDWARD 0. Hemodynamic relations to
metabolism in hypertension-Hemodynamic and myocardial functional
studies in the SHR (rat),
ROIHL-20572-02 0003 (CVB) FROHLICH, EDWARD D. Hemodynamic relations to
metabolism in hypertension-Cardiac output and organ blood flow in
hypertension (rats).
R0IHI-20S72-02 0007 (CVB) FROHLICH, EDWARD 0. llomod»n»niic lellliont to
metabolism in hypertension Drug ellecli on cardiac function and
hyperliopy Irat'^l
R01HL-20S72-02 0008 (CVB) FROHLICH, EDWARD D. Hemodynamic relations to
metabolism in hypertension Role ol nervous jyjtem in hemodynamic
function
ROlHL-205 74-03 (CVA) ST JOHN, WALTER M, OARTMOUIH MEDICAL SCHOOL,
DFPARIMfNI OF PHYSIOIOGY, HANOVER. N H Brain stem integration
ol chcmoieceplor activity (cats)
R23HL-20576-01 (YIP) JOHNSON, LARRY R, SCIENCES CENTER. 3181 S W SAM
JACKSON PARK ROAD. PORTLAND, OREGON Airway turbulence and pul
monary oxygen exchange
R0)HL-20577-03 (HEM) WILUNGHAM, ALLAN K, KIRKSVIllE COLL OF
OSTEOPATHIC. 800 WEST JEFFERSON STREET. KIRKSVILLE. MO The
mechanism ol action ol vilamin K
R01HI-20S79.02 (MCHA) KOZIKOWSKI, ALAN P, UNIVERSITY OF PITTSBURGH.
DEPARTMENT OF CHEMISTRY. PinSBURGH. PA Synthesis ol therapeu
tically important alkaloids
POlHl.20581-01 (HLBA) BEVAN, JOHN A, UNIVERSITY OF CALIFORNIA. PHAR
MACOLOGY DEPARTMENT. LOS ANGELES. CALIF Vascular neuroeflector
mechanisms in health and disease
P01HL-20S81-01 0001 (HLBA) BEVAN, JOHN A. Vascular neuroellector
mechanisms in health and disease Vascular neuroeffector mechanism
(rabbits)
POIHL-20S81-OI 0002 (HLBA) BEVAN, ROSEMARY D. Vascular neuroeffector
mechanisms in health and disease Trophic interaction between adre-
nergic nerves and vascular smooth muscle
P01HL-20S81-01 0003 (HLBA) DUCKLES, SUE P. Vascular neuroeffector
mechanisms in health and disease -Cerebrovascular neuroeffector
characteristics (animals)
P01HL-20S81-01 0004 (HLBA) SU, CHE. Vascular neuroeflector mechanisms in
health and disease -Neuroeffector characteristics ol mesenteric and
pulmonary blood vessels (rabbits)
P01HL-20581-01 0005 (HLBA) BEVAN. ROSEMARY D. Vascular neuroeffector
mechanisms in health and disease -Changes in the neuroeffector
mechanism in hypertension (rabbits)
P01HL-20581-01 0006 (HLBA) DEQUATTRO, VINCENT I. Vascular neuroeffector
mechanisms in health and disease -Neuroeffector mechanism in arte-
ries and veins in hypertension (human),
P01HL-20581-01 9001 (HLBA) BEVAN, ROSEMARY D. Vascular neuroeffector
mechanisms in health and disease-Morphology core,
P01HL-205B1-01 9002 (HLBA) SU, CHE. Vascular neuroeffector mechanisms in
health and disease-Biochemistry core
P01HL-20592-02 (HEPA) FOZZARD, HARRY A, UNIVERSITY OF CHICAGO. 950
EAST 59TH STREET. BOX 423 . CHICAGO. ILL, Cell biology of cardiac
and skeletal muscle,
P01HL-20592-02 0001 (HEPA) TAYLOR, EDWIN WILLIAM. Cell biology of car
diac and skeletal muscle -Molecular mechanism of muscle contraction
(animals),
POlHL-20592-02 0003 (HEPA) COHEN, CHARLES J. Cell biology of cardiac and
skeletal muscle-Cellular magnesium and anion activities in ion-
specific microelectrodes (frogs),
P01HL-20S92-02 0004 (HEPA) FOZZARD, HARRY A. Cell biology of cardiac and
skeletal muscle-Excitation, conduction and contraction-Modelling in
Purkinje fibers.
POlHL-20592-02 0005 (HEPA) FOZZARD, HARRY A. Cell biology of cardiac and
skeletal muscle -Quantitative voltage studies,
POlHL-20592-02 0006 (HEPA) PAGE, ERNEST. Cell biology of cardiac and
skeletal muscle-Permeability and ultrastructure of cardiac nexuses
(rabbits, cattle, rats).
POlHL-20592-02 0010 (HEPA) PAGE, ERNEST. Cell biology of cardiac and
skeletal muscle-Mitochondrial genesis during myocardial cell hyper-
trophy and hyperplasia (rats).
POlHL-20592-02 0011 (HEPA) RABINOWITZ, MURRAY. Cell biology of cardiac
and skeletal muscle-Myosin and cytochrome oxidase messenger RNAs
(chicken).
P01HL-20S92-02 0012 (HEPA) FORD, LINCOLN E.
skeletal muscle -Contractile properties
(frogs).
POlHL-20592-02 0013 (HEPA) FORD, LINCOLN E.
skeletal muscle-Sarcoplasmic reticulum
(frogs).
POlHL-20592-02 0014 (HEPA) PAGE, ERNEST. Cell biology of cardiac and
skeletal muscle-Core laboratory.
ROlHL-20594-02 (CVB) ERDOS. ERVIN G. UNIVERSITY OF TEXAS. 5323 HARRY
HINES BOULEVARD. DALLAS. TEX. Renal enzymes that regulate blood
pressure (human, rats).
ROlHL-20597-02 (CVB) MIRVIS. DAVID M. DOBBS MED RESEARCH INSTITUTE.
951 COURT AVENUE. MEMPHIS. TENN, Electrophysiologic correlates of
myocardial ischemia (human, dogs, rabbits),
R01HL-20S98-03 (CVA) BACHE. ROBERT J. UNIVERSITY OF MINNESOTA. BOX 194
- MAYO MEMORIAL BLDG. MINNEAPOLIS. MINN. The coronary vascular
response to ischemia (dogs, pigs),
ROlHL-20604-03 (CVB) JOHNSON. EUGENE M. JR, WASHINGTON UNIVERSITY.
660 SOUTH EUCLID. ST LOUIS. MO, Sympathedomy-Cardiovascular
and molecular pharmacology (animals),
ROIHL-20605-02 (PHY) BOHLEN, HAROLD G, INDIANA UNIVERSITY. 1100 WEST
MICHIGAN STREET. INDIANAPOLIS. IND. Microvascular responses during
intestinal absorption (rats),
ROlHL-20607-02 (CVA) OSTRANDER, LEE E, RENSSEUER POLYTECHNIC INST,
CTR FOR BIOMEDICAL ENGINEERING. TROY. N Y. Tissue analysis by
mass spectrometer (dogs),
ROlHL-206 10-02 (CVB) KAYE, MICHAEL P, MAYO FOUNDATION. 200 FIRST STREET
SOUTHWEST. ROCHESTER. MINN. Nerve growth factor and obstructive
cardiomyopathy (dogs),
ROlHL-20611-02 (CVA) DOUGLAS, JAMES S, JOHN B PIERCE FOUNDATION. 290
CONGRESS AVENUE. NEW HAVEN. CONN. Airway smooth muscle and
cyclic nucleotides.
ROlHL-206 12-02 (CVA) CHENEY, FREDERICK W, JR, UNIVERSITY OF WASHING
TON. ANESTHESIOLOGY DEPARTMENT. SEAHLE. WASH, Chronic animal
model of pulmonary vascular injury (dogs).
ROlHL-20613-02 (PHY) HUNTSMAN, LEE L, UNIVERSITY OF WASHINGTON, CENTER
FOR BIOENGINEERING, SEATTLE, WASH, Mechanical properties of iso-
lated myocardium.
Cell biology of cardiac and
of skinned muscle fibers
Cell biology of cardiac and
skinned muscle cells
PROJECT NUMBER AND INVESTIGATOR ADDRESS
570
I
ROIHl-20622-02 (TOX) MEHENDALE, HARIHARA M, UNIVERSITY OF MISSISSIP
PI, 2500 NORTH STATE STREET. JACKSON, MISS. Pulmonaty uptake
and accumulation of drugs (rabbits, rats).
R01HL-20629-02 <SGYB) BOURLAND, JOE D, PURDUE UNIVERSITY, BIOMEDICAL
ENGINEERING CENTER , WEST LAFAYETTE, IND. Catheter ventricular
defibrillation studies (dogs).
R01HL-20630-03 (CVB) COLE, JAMES S, UNIVERSITY OF KENTUCKY, CARDIOLOGY
SECTION, LEXINGTON, KY. Development of a pulsed Doppler velocity
detector (human, animals).
R01HL-20632-02 (SGYB) lONGINI, RICHARD I, CARNEGIE-MELLON UNIVERSITY
5000 FORBES AVENUE, PIHSBURGH, PA. An optimal fetal heart moni-
tor (human).
R01HL-20634-01 (AFY) NADEl, ETHAN R, JOHN B PIERCE FDN UBORATORY 290
CONGRESS AVENUE, NEW HAVEN, CONN. Blood volume and venous
return in thermal strain (human).
R01HL-2063S-03 (HED) MINOR, RONALD R, CORNELL UNIVERSITY. DEPARTMENT
OF PATHOLOGY, ITHACA, N Y Factors in lung development (rat and
chick embrvo).
ROIHl-20637.02 (EDC) JENKINS, C DAVID, BOSTON UNIVERSITY, 720 HARRISON
AVENUE, BOSTON, MASS. Recovery after heart surgery-Bio-behavioral
factors (human).
ROlHL-20643-02 (CVA) SHAY, JERRY W, UNIVERSITY OF TEXAS, 5323 HARRY
HINES BOULEVARD, DALUS, TEX. Analysis of heart cell contraction
(rats).
ROIHL-20645-OI (CVB) PHILLIPS, GERALD B, ROOSEVELT HOSPITAL, 428 WEST
59TH STREET, NEW YORK, N Y. Etiology of myocardial infaction
(human).
R01HL-20648-OI (CVA) DOWNEY, JAMES M, UNIVERSITY OF SOUTH ALABAMA,
307 UNIVERSITY BOULEVARD, MOBILE, ALA. Physical factors and coro-
nary flow (dogs).
R01HL-20652-01 (CVA) BUTLER, JOHN, UNIVERSITY OF WASHINGTON, DEPART-
MENT OF MEDICINE RM-12, SEATTLE, WASH. Sites of leakage in pul-
monary edema (dogs).
ROIHL-20655-02 (OBR) PRICE, KENNETH f, UNIV OF TEXAS HLTH SCIENCE CTR.
5323 HARRY HINES BOULEVARD, DALLAS, TEX. Autonomic predictors of
hypertension in children.
ROIHL-20658-01 (BIO) JACOBUS, WILLIAM E, JOHNS HOPKINS SCHOOL OF MED,
725 N WOLFE STREET, BALTIMORE, MD. Myocardial energy transport-
Creative kinase (human, cattle, dog).
R01HL-20662-02 (EDC) TAYLOR, HENRY, UNIVERSITY OF MINNESOTA, STADIUM
GATE 27, MINNEAPOLIS, MINN. Physical activity, fitness and
epidemiology of CHD.
R01HL-20663-02 (AFY) JOHNSON, JOHN M, UNIVERSITY OF TEXAS, 7703 FLOYD
CURL DRIVE, SAN ANTONIO, TEX Regulation of skin blood flow in
man.
R01HL-20666-02 (SSS) STRACHER, ALFRED, S U N Y - DOWNSTATE MEDICAL CT,
450 CURKSON AVENUE, BROOKLYN, N Y. Cell biology of platelet
preservation (human).
R01HL-20674-02 (RAD) WAGNER, HENRY N, JR, JOHNS HOPKINS UNIVERSITY,
615 NORTH WOLFE STREET, BALTIMORE, MD. Evaluation of cardiac
function v»ith radioactive tracers.
R01HL-2067S-02 (PTHA) GOLDE, DAVID W, UNIVERSITY OF CALIFORNIA, DEPART
MENT OF MEDICINE, LOS ANGELES, CALIF. Alveolar macrophage func-
tion in man.
R0)HL-20677-02 (RAD) JONES, ROBERT H, DUKE UNIVERSITY, P 0 BOX 2986,
DURHAM, N C. Radionuclide studies in congenital heart disease.
R01HL-20678-02 (AFY) ATKINS, JAMES M, UNIVERSITY OF TEXAS, 5323 HARRY
HINES BOULEVARD, DALLAS, TEX. Cardiovascular adaptation to stress
in disease states (dogs).
ROIHl-20685-02 (CVB) HANSON, KENNETH M, OHIO STATE UNIVERSITY, 333
WEST lOTH AVENUE, COLUMBUS, OHIO. Pittitary-adrenergic-ovarian
vasomotor interaction (dogs).
R01HL-20690-02 (CVA) BUTLER, JOHN, UNIVERSTY OF WASHINGTON, DEPART-
MENT OF MEDICINE, SEATTLE, WASH. Pulmonary hemodynamics in
lung edema during PEEP (dogs).
ROIHL-20695-02 (SSS) WHITE, JAMES G, UNIVERSITY OF MINNESOTA, BOX 479
MAYO MEMORIAL BUILDING, MINNEAPOLIS, MINN. Stored plateletes
(human).
ROIHL-20708-02 (PHY) NATHAN, RICHARD D, TEXAS TECH UNIV SCH OF MED,
POST OFFICE BOX, LUBBOCK. TEX. Voltage clamp of embryonic heart
cell aggregates (rat and chick embryos).
R01HL-207n-01 (PHY) KROPP, DONNA L, NEW JERSEY MEDICAL SCHOOL, COL-
LEGE OF MED & DENTISTRY, NEWARK, N J. Structure-function relation-
ships in red cell NA-K pumps (goats).
ROIHL-207 12-02 (MET) KUEHL, KAREN S, UNIVERSITY OF VIRGINIA, SCHOOL OF
MEDICINE, CHARLOTFESVILLE, VA. Characterization of the B proteins
of serum lipoproteins (human).
ROIHl-20716-02 (SSS) POPOVIC, VOJIN P, EMORY UNIVERSITY, DEPARTMENT OF
PHYSIOLOGY, ATLANTA, GA Freezing and electromagnetic thawing of
platelets (rats).
ROIHL-20718-02 (SSS) PUSZKIN, SAUL, MOUNT SINAI SCH OF MEDICINE, lOOTH
STREET & FIFTH AVENUE, NEW YORK. N Y. Microstructural integrity of
stored human platelets
ROIHl-207 19-02 (CVA) WILL, DONALD H, COLORADO STATE UNIVERSITY. DEPT
OF PHYSIOLOGY & BIOPHYSIC, FORT COLLINS, COLO. Cold induced pul-
monary hypertension (cattle).
ROIHl-20720-02 (SGYB) WEINTRAUB, RONALD M, BETH ISRAEK HOSPITAL, 330
BROOKLINE AVENUE, BOSTON, MASS. Myocardial protection during car-
diopulmonary bypass (dogs).
ROIHl-20724-01 (EDC) SHAPIRO, AlVIN P, UNIVERSIYT OF PIHSBURGH, 3811
O'HARA STREET, PIHSBURTH, PA. Behavioral consequences of hyper-
tension (human).
R01HL-2072S-02 (PHY) GUNN, ROBERT B, THE UNIVERSITY OF CHICAGO, 951
EAST 58TH STREET, CHICAGO, ILL. Mechanisms and cellular functions
of ion transport
R01HL-20749-0I (CVB) ANDERSON, PAGE A, DUKE UNIVERSITY, BOX 3218.
DURHAM. N C. Developing heart -Biophysical aspects (sheep).
R01HL-20750-01 (HEM) ASAKURA, TOSHIO, CHILDRN'S HOSPITAL. 34TH STREET
& CIVIC CTR BLVD. PHILADELPHIA. PA. Studies m sickle cell disease
(human).
RO 1 81-2075 1-0 1 (MCHB) REGNIER, FRED E, PURDUE UNIVERSITY. DEPARTMENT
OF BIOCHEMISTRY. W UFAYEHE. IND. High speed liquid chromatog-
raphy of hemoglobins (human).
ROIHL-20754.02 (SGYA) SU, JUDY Y, UNIVERSITY OF WASHINGTON. RN 10 BB
1469. SEATTLE. WASH. Anesthetic-induced myocardial depression
(rabbits).
ROIHL-20761-02 (RAD) HILAL, SADEK K, NEUROLOGICAL INSTITUTE. 710 WEST
168TH STREET, NEW YORK, N Y. Study of cerebral blood flow with sta-
ble xenon and computerized tomography.
ROIHl-20764-02 (PBC) GALLOP. PAUL M, CHILDREN'S HOSPITAL, 300 LONGWOOD
AVENUE. BOSTON. MASS. Elastin and calcification in pulmonary and
vascular disease (human, mammals).
RI3HL-2076S-01 (NSS) NELSON, ERLAND R, UNIVERSITY OF MARYUND. SCHOOL
OF MEDICINE, BALTIMORE, MD. Eleventh Princeton Conference on
Cerebrovascular Disease (new Jersey).
R01HL-20766-02 (AFY) PROPPE, OUANE W, UNIVERSITY OF TEXAS. 7703 FLOYD
CURL DRIVE, SAN ANTONIO, TEX. Control of circulation in heat stress
(baboons).
R01HL-20768-02 (CVB) SCHMID, PHILLIP G, UNIVERSITY OF IOWA, DEPT OF IN-
TERNAL MEDICINE, IOWA CITY, IOWA. Mechanisms of circulatory regu-
lation in heart failure (guinea pigs).
R01HL-20773-02 (AFY) HIIDEBRANDT, JACOB, VIRGINIA MASON RESEARCH CTR,
1000 SENECA STREET. SEAmE, WASH, Surfactant, pulmonary edema,
and lung mechanics (rabbits).
R01HL-20782-01 (CVB) OLSSON, RAY A, USF COLLEGE OF MEDICINE, 12901
NORTH 30TH STREET, TAMPA, FU. Coronary flow regulation by
adenosine (rats, dogs).
R01HL-20783-02 (PHRA) DOUGLAS, JAMES S, JOHN B PIERCE FOUNDATION, 290
CONGRESS AVENUE, NEW HAVEN, CONN. Airway rcactivity-B-
adrenoceptors and prostaglandins (guinea pigs).
R01HL-20787-02 (PHRA) NEEDLEMAN, PHILIP, WASHINGTON UNIVERSITY, 660
SOUTH EUCLID, ST LOUIS, MO Thromboxanes and prostaglandins-
Biochemical pharmacology (rabbits, human).
ROIHL-20788-02 (SSS) PERSIDSKY, MAXIM D, INSTITUTES OF MEDICAL
SCIENCES, POST OFFICE BOX 7999, SAN FRANCISCO, CALIF. Preserva-
tion of human platelets for transfusion.
ROIHL-20793-02 (PHRA) SHIDEMAN, FREDERICK E, UNIVERSITY OF MINNESOTA,
105 MILLARD HALL, MINNEAPOLIS, MINN. Phospholipids and cardiac
receptor function.
R01HL-20794-02 (PC) ROTH, GERALD J, UNIVERSITY OF CONNECTICUT, DEPART-
MENT OF MEDICINE, FARMINGTON, CONN. Prostaglandin synthesis in
human platelets (also in sheep, rabbit).
R01HL-20800-17 (NEUB) COHEN, MORTON I, ALBERT EINSTEIN COLLEGE OF
MED. 1300 MORRIS PARK AVENUE, BRONX, N Y. Neural basis of
respiratory and vasomotor activity (cats).
ROIHl-20803-02 (SGYB) KOLFF, WILLIAM J, UNIVERSITY OF UTAH, BUILDING 518,
SALT LAKE CITY, UTAH. Intra-aortic balloon pumping (dogs, lambs,
cats).
R01HL-20807-02 (MET) FOGELMAN, ALAN M, UNIVERSITY OF CALIFORNIA. DE-
PARTMENT OF MEDICINE. LOS ANGELES. CALIF. Detection of familial
hypercholesterolemia (human).
R01HL-208 15-02 (CVA) DEMPSEY, JEROME A, UNIVERSITY OF WISCONSIN. DEPT
OF PREVENTIVE MEDICINE. MADISON. WIS. Validation of indirect tests
of small airways function (human, dogs, ponies).
ROIHL-208 18-02 (SSS) MURPHY. SCOTT, THOMAS JEFFERSON UNIVERSITY. 1015
WALNUT STREET. PHILADELPHIA, PA. Platelet storage at 22 degrees C
(human).
ROIHL-20826-02 (HEM) NAKEFF. ALEXANDER. WASHINGTON UNIVERSITY 510
SOUTH KINGSHIGHWAY, ST LOUIS, MO. Megakaryocyte proliferation and
its control (mice).
R01HL-20827-02 (CVB) MARCUS. MELVIN I, UNIVERSITY OF IOWA. DEPT OF IN-
TERNAL MEDICINE. IOWA CITY. IOWA. Effects of hypertrophy on the
coronary circulation (dogs).
R01HL-20829-02 (SGYB) FALSETTI. HERMAN I. UNIVERSITY HOSPITALS. DEPART-
MENT OF INTERNAL MED. IOWA CITY. IOWA. Fluid mechanics of heart
valve prostheses (dogs, human).
R01HL-2083S-02 (SGYB) GIDDENS, DON P, GEORGIA INSTITUTE OF TECH
AEROSPACE ENGINEERING, ATLANTA, GA. Signal analysis of turbulence
study in blood.
ROIHL-20846-02 (HEM) RADCLIFFE, ROBERT D, OKUHOMA MEDICAL RESEARCH
FDN, 825 N E 13TH, OKLAHOMA CITY, OKLA. Purification of bovine
plasminogen proactivator.
R01HL-20847-02 (CVA) CHERNIACK, NEIL S, VETERANS ADMINISTRATION HOSP.
10701 EAST BOULEVARD, CLEVELAND, OHIO. Respiratory neurochemi-
cal control (human, goats).
R01HL-20856-02 (SSS) CONRAD, MARCEL E, UNIVERSITY OF ALABAMA. UNIVERSI-
TY STATION, BIRMINGHAM, AU. Platelet transfusions-Usage and com-
plications (human).
ROIHL-20859-02 (PHRA) BILEZIKIAN, JOHN P, COLUMBIA UNIVERSITY, 630
WEST 168TH STREET, NEW YORK, N Y Beta adrenergic catecholamine
receptor.
R01HL-20861-01 (EXP) CORSON. SAMUEL A, OHIO STATE UNIVERSITY, 473 WEST
12TH AVENUE, COLUMBUS, OHIO. Cardio-respiratory-renal stress reac-
tions (dogs).
R01HL-20864-01 (CVB) GOOTMAN, PHYLLIS M, S U N Y AT BROOKLYN 450
CLARKSON AVENUE, BROOKLYN, N Y. Postnatal maturation of car-
diovascular regulatory system (minipig)
R01HL-20868-02 (PBC) MENDICINO, JOSEPH F, UNIVERSITY OF GEORGIA DE-
PARTMENT OF BIOCHEMISTRY, ATHENS, GA. Regulation of glycoprotein
biosynthesis in lung (swine).
R01HL-20869-01 (RAD) FRANKLIN, THOMAS D, JR, INDIANA UNIVERSITY. 1100
WEST MICHIGAN STREET, INDIANAPOLIS, IND Microvascular responses
to ultrasound.
ROIHl-208 72-02 (RAD) MILLER, NORMAN B, PENNSYLVANIA STATE UNIVERSITY
POST OFFICE BOX 30, STATE COLLEGE, PA. Multidimensional echo
imaging of the ischemic heart.
ROIHl-20875-02 (PTHA) MILLER, R DREW, MAYO FOUNDATION, 200 FIRST STREET
SOUTHWEST, ROCHESTER, MINN. Chronic obstructive pulmonary dis-
ease-Familial/genetic (human).
R0IHL-20878-02 (PTHA) SAYEED, MOHAMMED M, LOYOU UNIVERSITY, 2160
SOUTH FIRST AVENUE, MAYWOOD, ILL. Cellular aspects of lung injury
(rats, rabbits).
ROIHl-20882-02 (BBCB) HARMONY, JUDITH A, INDIANA UNIVERSITY, CHEMIS
TRY DEPARTMENT, BLOOMINGTON, IND. Interactions of plasma
lipoproteins with erythrocytes (Rhesus, human).
R01HL-20883-02 (CVB) STREETER, DANIEL 0, JR, CHILDREN'S ORTHOPEDIC
HOSPITAL, P 0 BOXC-5371, CARDIOLOGY, SEAHLE, WASH Fiber
geometry in hypertrophy and cardiomyopathy (human).
571
PROJECT NUMBER AND INVESTIGATOR ADDRESS
R0IHI-30S9J-03 (SOYI) ABRAMS, HERBIRT I. PETER BENT 6RIGHAM HOSPITAL.
721 HUNTINGTON AVFNUE. BOSTON. MASS Cineangiogiaphic studies
ol caidiovasculai system
R0)Hl-20a9S-03 0001 (SOYB) HESSEl, S J. Cineangiogiaphic studies ol cai
diovasculai system Videodensitometni and valvular tagufgitation
(human, dogs)
R01NL-20B9S-03 0002 (SOYB) HOIMAN. B I. Cineangiogtaphic studies of cai
diovasculai system Coionary disease Regional myocardial blood How
(human, dog)
R0IHI-3089S-03 0003 (SOYB) ADAMS, D F. Cineangiographic studies ol car
diovascular system Densitometry in coronary stenosis (human)
R01HL-20e9S-03 0004 (SOYB) HESSEl, S J. Cineangiographic studies ol car
diovascular system Cineangiography Coronary lesions and ventricular
(unction (human)
R01HL-20B9S-03 0005 (SOYB) ADAMS, D F. Cineangiographic studies ol car
diovascular system Computerized axial tomography Cardiac wall mo
tion and inlarction (dogs)
R0IHI-2089S-03 0006 (SGYB) SERUR, J R. Cineangiographic studies ol car
diovascular system Cardiomyopathy Hemodynamic. radiologic,
morphologic abnormalities (dog. rabbit)
R01HI-20B9S-03 0007 (SGYB) ABRAMS, HERBERT I. Cineangiographic studies
ol cardiovascular system Determinants of collateral tormation (dogs,
hamsters).
R0IHL-2089J-03 0008 (SGYB) lEVIN, D C. Cineangiographic studies ol car-
diovascular system Intercoronary anastomotic circulation-Stenosis
and occlusion (dogs)
R01HI-3089S-03 0009 (SGYB) HESSEL, S J. Cineangiographic studies ol car-
diovascular system Aortic changes in atheromatosis (rabbits).
R01HL-20895-03 0010 (SGYB) HOUENBERG, NORMAN K. Cineangiographic
studies ol cardiovascular system -Cortical necrosis and acute renal
lailure (human, dogs. rats, rabbits)
ROIHL-20895-03 0011 (SOYB) ABRAMS, HERBERT I. Cineangiographic studies
of cardiovascular system -Ventricular hypertrophy and preoutflow con-
traction (human, dogs).
R01HL-20898-02 (SSS) STRANDNESS, DONAID E, JR, UNIVERSITY OF WASHING
TON. DEPARTMENT OF SURGERY. SEAHLE. WASH. Ultrasonic evalua-
tion in direct arterial surgery (models, cattle, human).
ROIHL-20899-02 (SSS) STAMATOYANNOPOUIOS, GEORGE, UNIVERSITY OF
WASHINGTON. OEPARTIi/IENT OF MEDICINE RG-20. SEAHLE. WASH. Cel-
lular mechanisms of hemoglobin F regulation (human).
ROIHl-20902-02 (CBY) COHEN, WILLIAM D, HUNTER COLLEGE. 695 PARK AVE.
BOX 243. NEW YORK. N Y. Studies on marginal band system of
erythrocytes (amphibians, reptiles, fish),
R0)HL-20905-02 (SSS) WEATHERALL, DAVID J, RADCLIFFE INFIRMARY, NUFFIELD
DEPT OF CLINICAL MEO , OXFORD 0X2 LHE ENGUND. Synthesis of
fetal hemoglobin in erythroid cells (sheep, human).
ROIHl-20909-02 (BIO) LAZAROW, PAUL B, ROCKEFELLER UNIVERSITY. 1230
YORK AVENUE, NEW YORK, N Y. Clofibrate-enhanced lipid oxidation by
peroxisomes (rats),
R01HL-209 10-02 (SSS) CONNOR, WILLIAM E, UNIVERSITY OF OREGON, 3181 S W
SAM JACKSON PARK ROAD, PORTLAND. GREG. The alternative diet for
coronary disease prevention (human).
R01HL-20912-02 (SSS) POPP, RAYMOND A, OAK RIDGE NATIONAL LABORATORY,
POST OFFICE BOX Y, BIOLOGY DIV, OAK RIDGE, TENN. Control on non-
alpha chain synthesis in thassemic mice.
R01HL-20913-02 (SSS) OGAWA, MAKIO, MED UNIV OF SOUTH CAROLINA, 80
BARRE STREET, CHARLESTON, S C. Cell culture studies of
hemoglobinopathies (human).
ROIHl-20920-01 (HEM) DE SIMONE, JOSEPH, UNIVERSITY OF ILLINOIS, 1853
WEST POLK STREET, CHICAGO, ILL. Control of hemoglobin synthesis
(baboon).
R01HL-20922-02 (SSS) FORGET, BERNARD G, YALE UNIVERSITY. 333 CEDAR
STREET. NEW HAVEN, CONN. Control of human fetal hemoglobin
synthesis.
ROIHL-20924-02 (CVB) ROBERTSON, ABEL L, CASE WESTERN RESERVE UNIV.
2085 ADELBERT ROAD, CLEVELAND, OHIO Atherosclerosis and arterial
cell functions (human, rabbits).
R01HL-20925-01 (HEM) BUNN, H FRANKLIN, PETER BENT BRIGHAM HOSPITAL.
721 HUNTINGTON AVENUE, BOSTON, MASS. The acetylation of letal
hemoglobin (human).
R01HL-20939-02 (SSS) LEE, JOHN C, UNIVERSITY OF TEXAS, 7703 FLOYD CURL
DRIVE, SAN ANTONIO, TEX. Regulation of fetal hemoglobin in humans.
R01HL-20943-02 (RAD) HARELl, GEORGE S, STANFORD UNIVERSITY. DIAGNOSTIC
RADIOLOGY. STANFORD, CALIF. Comparision of microsphere and RBC
behavior in vivo,
P01HL-20948-02 (HEPB) BROWN, MICHAEL S, UNIVERSITY OF TEXAS, 5323
HARRY HINES BOULEVARD, DALLAS, TEX, Molecular basis of
cholesterol metabolism.
POIHL-20948-02 0001 (HEPB) BROWN, MICHAEL S. Molecular basis of
cholesterol metabolism -Biochemical and ultrastructural characteriza-
tion of LDL in human fibroblasts
POIHl-20948-02 0002 (HEPB) BROWN, MICHAEL S. Molecular basis of
cholesterol metabolism -LDL pathway in cell lines with informative
properties other than fibroblasts
POIHL-20948-02 0003 (HEPB) BROWN, MICHAEL S. Molecular basis of
cholesterol metabolism -LDL pathway in vivo (human, rats, guinea
pigs).
POIHL-20948-02 0004 (HEPB) GOLDSTEIN, JOSEPH L. Molecular basis of
cholesterol metabolism-Genetic analysis of the LDL pathway (human).
POIHL-20948-02 9001 (HEPB) GOLDSTEIN, JOSEPH L. Molecular basis of
cholesterol metabolism -Tissue culture core laboratory.
P01 Hl-20948-02 9002 (HEPB) ANDERSON, RICHARD G W. Molecular basis of
cholesterol metabolism -Microscopy core laboratory.
ROIHL-20954-02 (MET) ROHEIM, PAUL S, LOUISIANA STATE UNIVERSITY, 1100
FLORIDA AVENUE, NEW ORLEANS. LA. Hyperlipoproteinemia (rats,
human).
ROIHl-20956-02 (PHRA) STEER, MICHAEL L, BETH ISRAEL HOSPITAL. 330
BROOKLINE AVENUE. BOSTON. MASS, Early events following stimula-
tion of human platelets.
R01HL-20961-02 (GEN) NUTE, PETER E, UNIVERSITY OF WASHINGTON. DEPT OF
ANTHROPOLOGY. DH-05, SEAHLE, WASH. Hemoglobin Y-chain genes -
Evolution and inducibility (monkeys, human).
ROIHl-20963-01 (PTHA) THADEPALLi, HARAGOPAL, 12021 SOUTH WILMINGTON
AVENUE. LOS ANGELES, CALIF. Experimental lung abscess (rabbits).
R23HI-20968-02 (CVA) SAUNDIRS, NICHOLAS A, PEIER BfNI BRIGHAM
HOSPIIAI. /?! HUNIINGION AVfNUf, BOSTON. MASS Rejpirilory
failure Control and muir.le dy.funclion (human)
ROIHl-20971-10 (HEM) JAMIESON, GRAHAM A, AMERICAN NAIIONAl RED
CROSS, 9312 OLD GEORGEIOWN ROAD, BflHtSOA, MD Membrane
glycoproteins ol platelets and leukocytes (human)
ROIHl-20979-02 (SOYB) RADER, ROLAND D, UNIV OF SOUTHERN CALIFORNIA,
815 WEST 37IH STREET, LOS ANGELES. CALIF A novel pulsed Ooppler
llowmeter (dogs)
POIHl-30984.02 (HEPA) MORKIN, EUGENE, UNIVERSITY OF ARIZONA, INTERNAL
MEDICINE OFPT, TUCSON, ARIZ Cellular mechanisms in cardiac hyper
trophy
POIHL-20984-02 0001 (HEPA) MORKIN, EUGENE, Cellular mechanisms in car
diac hypertrophy Contractile proteins in cardiac hypertrophy (rabbits,
calves)
POIHL-20984-02 0002 (HEPA) RUPLEY, JOHN A. Cellular mechanisms in car
diac hypertrophy -Thermodynamic. Iluorescence. chemical modilication
ol hypertrophied heart myosin
POIHl-20984-02 0003 (HEPA) CUSANOViCH, MICHAEL A. Cellular
mechanisms in cardiac hypertrophy Fast kinetics of myosin ATPase
Irom normal and hypertrophied heart (rabbits),
POIHL-20984-02 0004 (HEPA) GOLL, DARREL E. Cellular mechanisms in cardiac
hypertrophy Myofibril accumulation in cardiac and vascular muscle
cells in hypertrophy
POIHL-20984-02 OOOS (HEPA) ROESKE, WILLIAM R. Cellular mechanisms in
cardiac hypertrophy Neurohumoral receptors in cardiac growth and
compensatory hypertrophy (animals)
POIHL-20984-02 0006 (HEPA) RUSSELL, DIANE H. Cellular mechanisms in car-
diac hypertrophy -Early biochemical aspects of cardiac hypertrophy
(rats).
POIHL-20984-02 9001 (HEPA) MORKIN, EUGENE. Cellular mechanisms in car-
diac hypertrophy-Animal models and preparation ol contractile
proteins.
POIHL-20984-02 9002 (HEPA) ROESKE, WILLIAM R. Cellular mechanisms in
cardiac hypertrophy -The heart in organ culture.
P60HL-20985-01 (SRC) MENTZER, WILLIAM C, JR, SAN FRANCISCO GENERAL
HOSPITAL, 1001 POTRERO AVENUE, SAN FRANCISCO, CALIF Northern
California sickle cell center.
P60HL-20985-01 0001 (SRC) TEMPLE, PATRICIA C. Northern California sickle
cell center-Sickle cell anemia quality assurance program.
P60HL-20985-01 0002 (SRC) AMMANN, ARTHUR J. Northern California sickle
cell center-Immunization with polyvalent pneumococcal polysaccharide
vaccine (human).
P60HL-20985-01 0003 (SRC) BRADLEY, THOMAS B. Northern California sickle
cell center-Kinetics of sickling and clinical manifestations in sickling
disorders (human).
P60HL-2098S-01 0004 (SRC) CLARK, MARGARET R. Northern California sickle
cell center-Characterization of irreversibly sickled cells (human)
P60HL-20985-01 0005 (SRC) KAN, YUET WAI. Northern California sickle cell
center -Molecular mechanism of alpha thalassemia-Relation to sickle
cell anemia (human).
P60HL-20985-01 0006 (SRC) MENTZER, WILLIAM C. Northern California sickle
cell center-Antisickling properties of imidoesters (human, rats).
P60HL-20985-01 0007 (SRC) PETZ, LAWRENCE D. Northern California sickle cell
center-lmmunohematologic abnormalities in sickle cell anemia
(human).
P60HL-20985-01 0008 (SRC) PERSON, RONALD. Northern California sickle cell
center-Demonstration community program-Patient ambudsman.
P60HL-20985-01 0009 (SRC) MENTZER, WILLIAM C. Northern California sickle
cell center-Patient services (children, adults).
P60HL-20985-01 0010 (SRC) KAN, YUET WAI. Northern California sickle cell
center-Prenatal diagnosis of sickle cell anemia.
P60HL-20985-01 0011 (SRC) WEDLOW, PEGGY. Northern California sickle cell
center-SNMA community education program.
ROIHL-20989-01 (CVA) WANNER, ADAM, MOUNT SINAI MEDICAL CENTER, 4300
ALTON ROAD. MIAMI BEACH, FLA. Pathophysiology of bronchial asthma
(sheep, dogs).
POIHl-20993-02 (HEPB) THOMAS, WILBUR A, ALBANY MEDICAL COLLEGE. 47
NEW SCOTUND AVENUE. ALBANY. N Y Population dynamics ol arteri-
al cells in atherogenesis.
POIHL-20993-02 0001 (HEPB) THOMAS, WILBUR A. Population dynamics ol ar-
terial cells in atherogenesis -Arterial SMC population dynamics in
atherogenesis (swine)
POIHL-20993-02 0002 (HEPB) SCOTT, R FOSTER. Population dynamics of arteri-
al cells in atherogenesis -Arterial endothelial dynamics in atherogene
sis (swine)
POIHL-20993-02 0003 (HEPB) THOMAS, WILBUR A. Population dynamics of ar-
terial cells in atherogenesis -Clonal phenomena in atherogenesis
(human, hares),
POIHL-20993-02 0004 (HEPB) KIM, DONG N. Population dynamics of arterial
cells in atherogenesis -Modifications of cholesterol balance related to
arterial cell divisions (swine).
POIHL-20993-02 0005 (HEPB) LEE, KYU T. Population dynamics of arterial cells
in atherogenesis-Drugs other than hypolipidemic drugs affecting
atherosclerosis (swine, rabbits).
POIHl-20993-02 0006 (HEPB) DAOUD, ASSAAD S. Population dynamics of ar-
terial cells in atherogenesis-Mcchanism of regression of atherosclero-
sis by diet and injury (swine).
POIHL-20993-02 0007 (HEPB) FRITZ, KATHERINE E. Population dynamics of ar-
terial cells in atherogenesis-lnteraction of lipoproteins in
hypercholesteremia (human, swine).
POIHl-20993-02 0008 (HEPB) IMAI, HIDESHIGE. Population dynamics of arterial
cells in atherogenesis-Angiotoxicity of cholesterol oxidation in
atherogenesis (rabbits).
POIHL-20993-02 0009 (HEPB) REINER, JOHN M. Population dynamics of arteri-
al cells in atherogenesis-Mathematical biology-Core.
POIHL-20993-02 0010 (HEPB) LEE, KYU T. Population dynamics of arterial cells
in atherogenesis-Animal care and development and standardization of
animal models -Core.
POIHL-20993-02 0011 (HEPB) FLORENTIN, RODOLFO A. Population dynamics
of arterial cells in atherogenesis-Light and electron microscopy
laboratories -Core.
POIHL-20993-02 0012 (HEPB) KLM, DONG N. Population dynamics of arterial
cells in atherogenesis-Chemistry laboratory-Core.
PROJECT NUMBER AND INVESTIGATOR ADDRESS
572
P01HL-20993-02 0013 (HEPB) THOMAS. WIIBUR A. Population dynamics of ar
ferial cells in atherogenesis-Administration -Core.
l>01HL-20994-02 (HEPA) KIMBEL. PHIIIP, ALBERT EINSTEIN MEDICAL CENTER
YORK & TABOR ROADS. PHIUDELPHIA, PA. Dynamics of neutrophil
elastase in the lung.
P01HL-20994-02 0001 (HEPA) COHEN, AllAN B. Dynamics of neutrophil
elastase in the lung-Dynamics of neutrophil elastase in normal
animals (dogs, rabbits).
POlHL-20994.02 0002 (HEPA) RODMAN, THEODORE. Dynamics of neutrophil
elastase in the lung-Neutrophil and neutrophilic elastase in human
lungs.
POlHL-20994.02 0003 (HEPA) WEINBAUM, GEORGE. Dynamics of neutrophil
elastase in the lung-Neutrophil elastase flux in models of lung dis-
ease (dogs).
POlHL-20994-02 0004 (HEPA) COHEN, AllAN B. Dynamics of neutrophil
elastase in the lung-Mechanism of enzyme inhibition by alpha-1 an-
titrypsin (cattle).
POlHl-20994.02 0005 (HEPA) KUEPPERS, FRIEDRICH. Dynamics of neutrophil
elastase in the lung-Protease inhibitors in pulmonary inflammation
and emphysema (rabbits).
POIHl-20994-02 0006 (HEPA) KUEPPERS, FRIEDRICH. Dynamics of neutrophil
elastase in the lung-Protease inhibitors in human bronchial mucus.
POlHL-20994.02 0007 (HEPA) WEINBAUM, GEORGE. Dynamics of neutrophil
elastase in the lung -The etiology of experimental emphysema (dogs).
POlHl-20994-02 0008 (HEPA) KIMBEL, PHILIP. Dynamics of neutrophil elastase
in the lung-structure-function correlation in experimental emphysema
(human, dogs).
POlHl-20994-02 0009 (HEPA) ROSENBIOOM, JOEL. Dynamics of neutrophil
elastase in the lung-Biosynthesis and degradation of elastin in
emphysema (human, hamsters).
POlHL-20994-02 9001 (HEPA) JAMES, HAROLD. Dynamics of neutrophil
elastase in the lung-Biochemistry and immunology core.
POIHl-20994-02 9002 (HEPA) DAMIANO, VICTOR V. Dynamics of neutrophil
elastase in the lung -Ultrastructural core.
POlHl-20994-02 9003 (HEPA) PETERSEN, ROBERT O. Dynamics of neutrophil
elastase in the lung-Autoradiography-Histology core.
R01HL-20996-02 (MCHB) GOEDKEN, VIRGIL L, FLORIDA STATE UNIVERSITY, DE-
PARTMENT OF CHEMISTRY, TALLAHASSEE, FLA. Structural and reactivi-
ty of iron and cobalt complexes.
ROIHl-21001-01 (SGYB) COOPER, STUART I, UNIVERSITY OF WISCONSIN, DEPT
OF CHEMICAL ENGINEERING. MADISON, WISC. Protein and thrombus
deposition on vascular grafts.
P50HL-2 1006-02 (HLBA) GOODMAN, OE WITT S, COLUMBIA UNIVERSITY, 630
WEST 168TH STREET, NEW YORK, N Y. Specialized center of research
in arteriosclerosis.
P50HI-2 1006-02 0001 (HLBA) GOODMAN, DEWITT S. Specialized center of
research in arteriosclerosis-Clinic and core program.
PSOHl-2 1006-02 0002 (HLBA) SMITH, FRANK R. Specialized center of research
in arteriosclerosis-Turnover and metabolism of cholesterol in man.
P50HL-2 1006-02 0003 (HLBA) GOODMAN, DEWITT S. Specialized center of
research in arteriosclerosis -Transport of vitamin A in plasma (human,
rat).
P50HL-2 1006-02 0004 (HLBA) GOODMAN, DEWITT S. Specialized center of
research in arteriosclerosis-Regulation of growth of human arterial
smooth muscle cells by platelets.
P50HL-21006-02 0005 (HLBA) CANNON, PAUL S. Specialized center of
research in arteriosclerosis-Regional myocardial perfusion in patient
with coronary artery disease (also dogs).
P50HL-2 1006-02 0006 (HLBA) NOSSEL, HYMIE I. Specialized center of research
in arteriosclerosis-lntravascular coagulation and thrombosis in hyper-
lipidemia (human).
R01HL-2I008-02 (TOX) CHAPPIE, PAUL J, W ALTON JONES CELL SCI CTR, OLD
BARN ROAD, LAKE PLACID, N Y. Effect of pollutants on organotypic
lung cultures (rats).
ROIHl-2 1009-02 (TOX) SMITH, JAMES R, W ALTON JONES CELL SCI CENTER. OLD
BARN ROAD, UKE PUCID, N Y. Effects of air pollutants on lung cells
in culture (rats).
R01HL-210IO-02 (SSS) STAMIER, JEREMIAH, NORTHWESTERN UNIVERSITY, 303
EAST CHICAGO AVENUE, CHICAGO, ILL. Glycemia. other traits and CV
death in 40,000 persons.
ROlHL-21014-01 (PHRA) LEE, KWANG S, S U N Y - DOWNSTATE MED CTR, 450
CLARKSON AVENUE, BROOKLYN, N Y. Mechanism of the inotropic ac-
tion of cardiac glycosides.
P01HL-21016-02 (HEPB) NAGEL, RONALD L, ALBERT EINSTEIN COLLEGE OF MED,
1300 MORRIS PARK AVENUE, BRONX, N Y. Sickle cell anemia and
other hemoglobinopathies.
POlHL-2 101 6-02 0001 (HEPB) NAGEL, RONALD L. Sickle cell anemia and other
hemoglobinopathies -Supramolecular models of Hb S-Mutational and
EM approach.
POlHL-2 101 6-02 0002 (HEPB) ELBAUM, DANEK. Sickle cell anemia and other
hemoglobinopathies-Molecular events proceeding gelation of Hb S.
POlHL-21016-02 0003 (HEPB) BOOKCHIN, ROBERT M. Sickle cell anemia and
other hemoglobinopathies-Role of non-S hemoglobin in gelation and
sickling.
POlHL-21016-02 0004 (HEPB) HARRINGTON, JOHN. Sickle cell anemia and
other hemoglobinopathies-Kinetics of sickling.
POIHL-2 101 6-02 0005 (HEPB) WITTENBERG, JONATHAN. Sickle cell anemia
and other hemoglobinopathies-Ligand kinetics in normal and Hb S
containing erythrocytes (human)
POIHL-21016-02 0006 (HEPB) BOOKCHIN, ROBERT M. Sickle cell anemia and
other hemoglobinopathies Analysis of the oxygen dissociation curve of
Hb S'Containing red cells
POIHL-21016-02 0007 (HEPB) BOOKCHIN, ROBERT M. Sickle cell anemia and
other hemoglobinopathies-Cellular determinants of red cell sickling
POIHL-21016-02 0008 (HEPB) ROTH, EUGENE F, JR. Sickle cell anemia and
other hemoglobinopathies The clinical variations of sickle cell
anemia
MIHl-21016-02 0009 (HEPB) ROTH, EUGENE F, JR. Sickle cell anemia and
other hemoglobinopathies-Nitrogen mustards and their potential use
as antisickling agent
POIHl-21016-02 0010 (HEPB) ELBAUM, DANEK. Sickle cell anemia and other
hemoglobinopathies -Alkylureas as potential antisickling agents.
POIHl-21016-02 0011 (HEPB) NAGEL, RONALD L. Sickle cell anemia and other
hemoglobinopathies-Metabolic effects of antisickling agents
(hamsters).
POIHL-21016-02 0012 (HEPB) SKOUITCHI, ARTHUR. Sickle cell anemia and
other hemoglobinopathies-Stlmulation of Hb F synthesis in a per-
manent cell line.
POIHL-21016-02 0013 (HEPB) BAEZ, SILVIO. Sickle cell anemia and other
hemoglobinopathies-Microcirculatory response to sickle cell treated
with anti-sickling agents (rats).
POIHL-21016-02 0014 (HEPB) NAGEL, RONALD L. Sickle cell anemia and other
hemoglobinopathies-Human hemoglobin mutants with abnormal ox-
ygen binding.
POIHL-21016-02 0015 (HEPB) PEISACH, JACK. Sickle cell anemia and other
hemoglobinopathies-EPR study of NO derivatives of Hb Beth Israel
(human).
POIHL-21016-02 0016 (HEPB) NADEL, ALFRED J. Sickle cell anemia and other
hemoglobinopathies-The treatment of sickle cell retinopathy (human).
POIHL-21016-02 0017 (HEPB) NAGEL, RONALD L. Sickle cell anemia and other
hemoglobinopathies-The hereditary clinic core.
POIHL-21016-02 0018 (HEPB) TELLEZ-NAGEL, ISABEL. Sickle cell anemia and
other hemoglobinopathies-Scanning and transmission electron
microscopy.
POIHL-21016-02 0019 (HEPB) NAGEL, RONALD L. Sickle Cell anemia and other
hemoglobinopathies-Administration core.
ROlHL-21030-01 (CVB) JANIS, RONALD A, NORTHWESTERN UNIVERSITY. 303
EAST CHICAGO AVENUE, CHICAGO, ILL. Calcium regulation and hyper-
tension (rats).
ROIHL-2 1032-02 (CVA) CRAWFORD, DONALD W, UNIV OF SOUTHERN CALIFOR-
NIA, 2025 ZONAL AVENUE. LOS ANGELES, CALIF. Injury, wall thickness,
and arterial wall oxygenation (dogs, rabbits).
R01HL-21034-01 (CVA) CONRAD, MARGARET C, EASTERN VIRGINIA MEDICAL
SCH, POST OFFICE BOX 1980, NORFOLK, VA. Compensatory responses
to arterial occlusion (dogs).
ROlHL-21038-01 (CVA) JONES, JANICE L, CASE WESTERN RESERVE UNIV. 2119
ABINGTON ROAD, CLEVEUND, OHIO. Electrically induced cardiac EM-
histochemical changes (animals).
ROlHl-2 1039-02 (EDC) WEST, KELLY M, UNIVERSITY OF OKLAHOMA, POST OFFICE
BOX 26901, OKUHOMA CITY, OKLA. Vascular lesions of diabetes in
Oklahoma Indians.
R23HL-21042-01 (CVA) KOSTREVA, DAVID R, VETERNAS ADMINISTRATION
CENTER, RESEARCH SERVICE 151, WOOD, WIS. Cardiopulmonary
reflexes and their anatomical basis (dogs).
ROIHL-2 1047-01 (EVR) GAUNTT, CHARLES J, UNIVERISYT OF TEXAS, 7703 FLOYD
CURL DRIVE. SAN ANTONIO. TEX. Studies of coxsackievirus-induced
myocarditis in mice.
R23HL-2 1050-02 (CVA) PAVLIN, DOROTHY J, UNIVERSITY OF WASHINGTON,
BB1469 HEALTH SCIENCES BLDG, SEATTLE, WASH. Mechanisms of re-
expansion pulmonary edema (rabbits).
R23HL-2 105 1-02 (PHRA) LIMBIRD, LEE E, DUKE UNIVERSITY, BOX 3297, DURHAM,
N C. Adrenergic receptors and the adenylate cyclase system (frog
RBC).
R0IHL-210S2-01 (PHRA) GORRY, G ANTHONY, BAYLOR COLLEGE OF MEDICINE
1200 MOURSUND AVENUE, HOUSTON. TEX. Evaluation of a digitalis
therapy advisor.
R23HL-2 1066-02 (CVB) CAMPBELL, WILLIAM B, UNIVERSITY OF TEXAS, 5323
HARRY HINES BOULEVARD, DALLAS, TEX. Angiotensin and prostaglan-
din control of aldosterone (rats).
ROIHl-2 107 1-02 (SGYB) BONCHEK, LAWRENCE I, MECICAL COLLEGE OF
WISCONSIN, 8700 WEST WISCONSIN AVENUE. MILWAUKEE. WIS.
Mechanisms of hypertension in coarctation of the aorta (dog).
ROIHL-2 1076-02 (SGYA) DEMLING, ROBERT H, UNIVERSITY OF WISCONSIN 1300
UNIVERSITY AVENUE, MADISON, WIS. Lung fluid, protein exchange
after hemorrhagic shock (sheep).
R23HL-2 1083-02 (PHRA) CASTLE, MANFORD C, EASTERN VIRGINIA MED
SCHOOL, POST OFFICE BOX 1980, NORFOLK, VA. Pharmacokinetics of
digoxin and digitoxin in humans (rats).
ROlHL-2 1088-02 (EDC) WILLIAMS, ROGER R, UNIVERSITY OF UTAH. DEPT OF IN-
TERNAL MEDICINE, SALT LAKE CITY, UTAH. Genetic patterns in deaths
from Ml and stroke in Utah.
R23HL-2 1089-02 (IMS) LEWIS, ROBERT A, ROBERT B BRIGHAM HOSPITAL 125
PARKER HILL AVENUE, BOSTON, MASS. Localization of mediators in
dispersed lung cells (guinea pigs, human).
ROIHL-2 1092-02 (CVB) CARRETERO, OSCAR A, HENRY FORD HOSPITAL, 2799 W
GRAND BLVD, DETROIT, MICH. Factors other than renin in renal hyper-
tension (rats).
ROIHL-2 1094-01 (CVB) BOND, GARY C, MEDICAL COLLEGE OF GEORGIA, DEPT OF
PHYSIOLOGY, AUGUSTA, GA. Arterial baroreceptors and renal function
(dogs).
ROlHL-2 1095-02 (PBC) GLEISNER, JOHN M, VIRGINIA MASON RESEARCH
CENTER, 1000 SENECA STREET, SEAHLE, WASH. Enzymes of M tu-
berculosis and obstructive lung disease (human, rodents)
ROlHL-21096-02 (CTY) WISE, GARY E, UNIVERSITY OF MIAMI, P 0 BOX 520875,
MIAMI, FLA. Sickle cell crisis-Role of the erythrocyte membrane
(human).
ROlHL-2 1099-02 (CVA) RHO, JOON H, UNIV OF SOUTHERN CALIFORNIA. 1985
ZONAL AVENUE. LOS ANGELES. CALIF. Subcellular changes of blood
vessels in hypertension (rats).
ROlHL-21 103-01 (CVB) PRICE, JOEL M, UNIVERSITY OF SOUTH FLORIDA, 12901
NORTH 30 STREET, TAMPA, FLA. Parametric mechanical studies of
hyperlensive arteries (dogs, rats).
ROlHL-2 1105-02 (PHRA) ORLOWSKI, MARIAN, MOUNT SINAI SCHOOL OF
MEDICINE, lOOTH STREET & FIRH AVENUE. NEW YORK, N Y. Organ
specific drugs -Cardiovascular and renal effects (dogs).
ROlHL-21 112-02 (CVB) HORTON, RICHARD, UNIV OF SOUTHERN CALIFORNIA
2025 ZONAL AVENUE, LOS ANGELES, CALIF Aldosterone binding,
clearance, and secretion in man.
ROlHL-21 1 13-01 (HEM) JESTY, JOLYON, S U N Y - AT STONY BROOK, DEPT OF
MEDICINE-HEMATOLOGY, STONY BROOK, N Y. Control mechanisms in
coagulation (cattle).
ROlHL-21 115-01 (TOX) BLOCK, EDWARD R, J HILLIS MILLER HEALTH CENTER.
BOX J-225, GAINESVILLE. FLA. Prevention of 02 toxicity with superoxide
dismutase (rats).
R23HL-21 116-02 (PTHA) FRANSON, RICHARD C, VIRGINIA COMMONWEALTH
UNIV, BOX 877, RICHMOND. VA. Mechanisms of membrane and tissue
damage in lung (dogs, rabbits).
ROlHL-21 117-01 (AFY) GRAHAM, WILLIAM G, MARY FLETCHER UNIT, MEDICAL
CENTER HOSPITAL OF VT , BURLINGTON, VT. Altitude adaptation in
chronic lung disease (human).
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R23HL-2I167
R23HL-21I68
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R01HL-21I76
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R01HL-21I82'
R01HL-21187
R01HL-2n88
R23HI-21189-
R01HL-21I94.
ROIHl-21195
R23HL-21I96
R23HI-21197
R23HL-2I199
R23HI-2I203-
R23HI-21208
ROIHl-21209
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R23HL-212I2
R23HI-212I3-
573
.02 (PTHA) KAPIAN. JIRRY, UNIVERSITY Of CONNECTICUI. OEPARI
MEN! OE PHYSIOIOCV. FARMINCION. CONN Membone dynamics m
alveolm maciophiites ([.ibbits)
,-02 (PTHA) WEISIR. PHIIIP C, NAIIONAL ASIHMA CENTER. 1999 lU
UAN STREET, DENVER. COLO Exercise inducsd bionchospasm in chil
02 '(HEM) DANIEL, JAMES L, TEMPLE UNIVERSITY. 3400 NORTH
BROAD STREET. PHILADELPHIA. PA ATP utilization in platelet contiac-
tile mechanisms (human, rabbits)
02 (HEM) CHAO, TESSA I, LANKENAU HOSPITAL. CITY LINE & LAN
CASTER AVE. PHILADELPHIA. PA The antisickling ellects ol
imidoesteis
02 (PTHA) DAUBER, JAMES H, UNIVERSITY OF PENNSYLVANIA.
3600 SPRUCE STREET, PHILADELPHIA. PA Immune function and
librogenesis in silicosis (guinea pigs)
02 (PHY) lEE, CHIN O, CORNELL UNIVERSITY. 1300 YORK AVENUE.
NEW YORK, N Y Ion activities and transport in cardiac muscle cells
(sheep)
.02 (HEM) MC DONAGH, JAN M, UNIVERSITY OF NORTH
CAROLINA. SCHOOL OF MEDICINE. CHAPEL HILL. N C Molecular biolo-
gy of factor XIII (human)
-01 (CVA) WOODSIDE, KENNETH H, UNIVERSITY OF MIAMI. P 0
BOX 520875 BISCAYNE ANNEX . MIAMI. FU. Studies of pulmonay al-
veolar macrophage function (rabbits)
-02 (CVB) ROBERTS, lOU A, TEXAS TECH UNIV SCH OF MED, POST
OFFICE BOX 4569. LUBBOCK. TEX Response of atria to hyperosmolali-
ty Mechanisms (rabbits)
02 (PHY) DAVIS, BRIAN, UNIVERSITY OF CALIFORNIA. 1315 MOFFIH
HOSPITAL. SAN FRANCISCO. CALIF, Regulation of airway mucous
glands and ion transport (dogs, ascaris).
-02 (PHRA) PATTERSON, RANDOLPH E, MOUNT SINAI SCHOOL OF
MEDICINE. 5TH AVENUE 8. lOOTH STREET. NEW YORK. N Y, Ischemic
myocardium- Delivery of blood flow and drugs (dogs)
.02 (PTHA) LIEBERMAN, JACK, VETERANS ADMINISTRATION HOSP.
16111 PLUMMER STREET. SEPULVEDA. CALIF. Antitrypsin and other
causes of chronic lung disease.
.02 (CVA) THAMES, MARC D, UNIVERSITY OF IOWA. DEPARTMENT
OF INTERNAL MED. IOWA CITY. IOWA, Cardiac receptors with vagal C-
fiber atferents (cats).
-02 (AFY) OU, lO-CHANG, DARTMOUTH MEDICAL SCHOOL, DEPART-
MENT OF PHYSIOLOGY. HANOVER, N H. Pathophysiological effects of
hypoxia (rats).
-02 (CVB) ARONSON, RONALD S. ALBERT EINSTEIN COLL OF MED.
1300 MORRIS PARK AVENUE, BRONX, N Y. The electrophysiology of
cardiac hypertrophy (rats).
.01 (CVA) FRIEDMAN, MITCHELL, UNIVERSITY OF NORTH CAROLINA,
DIV OF PULMONARY DISEASES, CHAPEL HILL, N C. Hypoxemic respira-
tory failure-Physiologic evaluation (human, dogs).
-01 (BBCB) SUDDATH, FRED L, UNIVERSITY OF ALABAMA, UNIVERSI-
TY STATION, BIRMINGHAM, ALA. Molecular structure of human serum
transferrin.
-02 (PHY) WEISS, HARVEY R, RUTGERS MEDICAL SCHOOL, POST OF
FICE BOX 101. PISCATAWAY. N J. Regional oxygen consumption of
heart and other organs (animals).
■02 (CVA) LUMB, ROGER H, WESTERN CAROLINA UNIVERSITY. BOX
374B. CULLOWHEE. N C. Phospholipid exchange proteins in lung tis-
sue (lambs).
.01 (PHY) CALA, PETER M, UNIVERSITY OF CALIFORNIA, DEPT OF
HUMAN PHYSIOLOGY. DAVIS, CALIF. Volume regulation-Role of the
membrane potential (amphiuma).
-02 (CVB) HAMREIL, BURT B, UNIVERSITY OF VERMONT, GIVEN
BUILDING, BURLINGTON, VT. Active tension and shortening in cardiac
hypertrophy (rabbits).
-01 (CVB) HENRY, PHILIP D, WASHINGTON UNIVERSITY. 660 SOUTH
EUCLID AVENUE. ST LOUIS. MO. Potassium, norepinephrine, and coro-
nary arterial tone (dogs).
.02 (SGYB) BLACKSHEAR, PERRY I, JR, UNIVERSITY OF MIN-
NESOTA. MECHANICAL ENGINEERING DEPT. MINNEAPOLIS. MINN. Pulsa-
tory viater flux and endothelial cell desquamation.
.01 (CTY) MAKARSKI, JOSEPH S, BOSTON UNIVERSITY. 80 EAST
CONCORD STREET. BOSTON. MASS. Regulation of pulmonary endotheli-
al cell activities (human, cattle).
•02 (SGYB) WILSON, JOSEPH E, BISHOP COLLEGE. 3837 SIMPSON -
STUART RD. DALLAS. TEX. Development of antithrombogenic plastic
biomatenals
.02 (PHY) HARTZEIL, HARRISON C, JR, EMORY UNIVERSITY.
ANATOMY DEPARTMENT. ATUNTA, GA. Innervation of the heart-
Acetylcholine receptors (frogs).
-02 (PHRA) RHEE, HEE M, MEDICAL COLLEGE OF OHIO. C S 10008.
TOLEDO. OHIO. Digitalis induced arrhythmia and NAO KO-atpase activi-
ty (dogs).
-02 (CVA) MEIER, GEORGE D, TEMPLE UNIVERSITY. 3420 NORTH
BROAD STREET. PHILADELPHIA. PA. Right ventricular contraction and
relaxation (dogs).
-02 (AFY) RICE, DAVID A, OHIO STATE UNIVERSITY. VETERINARY
PHYSIO & PHARM DEPT. COLUMBUS. OHIO Sound transmission in
lung (dog)
.02 (PHRA) SYNHORST, DAVID P, UNIVERSITY OF UTAH. DEPART-
MENT OF PEDIATRICS. SALT LAKE CITY. UTAH Effect of vasoactive
agents on left to right shunts (lambs)
.02 (HEM) SWITZER, MARY E, DUKE UNIVERSITY, BOX 3705, DUR
HAM, N C Structure function relationships of human factor VIII
•02 (CVA) UEDTKE, A JAMES, PENNSYLVANIA STATE UNIVERSITY.
MILTON S HERSHEY MED CENTER. HERSHEY. PA. Alterations of
metabolism in ischemic myocardium (swine)
.01 (SGYB) HIIBERMAN, MARK, STANFORD UNIVERSITY. DEPART
MENT OF ANESTHESIA. STANFORD. CALIf Acute renal failure following
cardiac surgery (human)
.02 (BM) HARVATH, LIANA, V A WEST SIDE HOSPITAL, 820 SOUTH
DAMEN AVENUE, CHICAGO, ILL. Alveolar macrophage function in Pseu-
domonas infection (dgs)
.01 (PHY) STOUT, MARGUERITE A, NEW JERSEY MEDICAL SCHOOL.
100 BERGEN STREET, NEWARK, N J. A model for calcium homeostasis
in excitable tissue (marine worms).
R01HI-2I2)7-
R0)H1.21221-
R23HI-2122S
R23HI-2I234
R01HL-21239
ROIHl-21245
ROIHl-21246-
R23HL
R23HI
21247
■21251
R23HI-21253
R01HI-212S7-
ROIHl-21260
R23HI-21262
ROIHl-21270
R23HL-21271
ROIHl-21272
R01HL-21273
R01HL-21274
R01HL-21276
R01HL-21278
R23HL-21279
R01HL-21282-<
R01HL-21283-
R23HL-21291
R23HL-21292
R01HL-21293
ROIHl-21294
R23HI-21298-
R01HL-21303
ROIHl-21307-
ROIHl-21308
R01HL-21312
ROIHl-21314
R01HL-21318
ROIHl-21319-
PROJECT NUMBER AND INVESTIGATOR ADDRESS
01 (CTY) RUONICK, GARY W, YAlf UNIVERSITY. OEPARIMINI 01
PHARMACOIOGY. NfW HAVEN. CONN Ion ind 5 hydroxytryplamine
transport by platelets
02 (PHRA) HARRISON, OONAIO C, STANFORD UNIVERSITY, CAR
OIOLOGY DIVISION. SIANFORD. CAlIf Clinical antiarrhythmic and
pharmacodynamic studies
.02 (PBC) MECHAM, ROBERT P, WASHINGTON UNIVERSITY, 660
SOUTH EUCLID, ST LOUIS, MO Connective tissue precursor molecules
in the lung (rabbits, hamsters)
-02 (CVB) BOUCEK, ROBERT J, JR, VANOERBILT UNIVERSITY. DIV
Of PEDIATRIC CARDIOLOGY. NASHVILLE. TENN. The regulation ol car
diac hypertrophy (rabbits)
.02 (PHRA) SMITH, J BRYAN, THOMAS JEFFERSON UNIVERSITY.
1015 WALNUT STREET. PHILADELPHIA. PA Isolation and mechanism of
action of thromboxane A2 (human, rabbits)
.02 (AFY) TIPTON, CHARLES M, UNIVERSITY OF IOWA.
DEPT/PHYSIOLOGY AND BIOPHYSICS. IOWA CITY. IOWA Influence of
chronic exercise on hypertension (rats, primates)
02 (PC) CHANG, TA-YUAN, DARTMOUTH MEDICAL SCHOOL, OE
PARTMENT OF BIOCHEMISTRY. HANOVER. N H. Roles of cholesterol and
Its metabolic regulation (CHO cell mutants)
02 (PC) SLATER, EVE E, MASSACHUSETTS GENERAL HOSPITAL. 32
FRUIT STREET BOSTON, MASS Purification of renal renin (human)
-01 (PC) SMITH, FRED, NEW YORK MEDICAL COLLEGE, DEPARTMENT
OF PATHOLOGY, VALHALLA, N Y Metabolism of neutral lipids in the
pulmonary alveolus (rabbits).
.01 (COM) BALLARD, DANA H, UNIVERSITY OF ROCHESTER, DE
PARTMENT OF COMPUTER SCIENCE, ROCHESTER. N Y Anatomical
models in computer-aided image analysis.
-02 (PHY) OREM, JOHN M, TEXAS TECH UNIV SCH OF MED. POST
OFFICE BOX 4569. LUBBOCK. TEX. Breathing in sleep-Airway control
and blood gases (cats).
02 (CVB) RUDEl, LAWRENCE I, WAKE FOREST UNIVERSITY. BOW-
MAN GRAY SCHOOL OF MEDICINE, WINSTON-SALEM, N C. Risk factor
relationships of atherosclerosis (monkeys),
.02 (CVB) SUTKO, JOHN I, UNIVERSITY OF TEXAS. 5323 HARRY
HINES BOULEVARD. DALLAS. TEX. Sodium-calcium interactions in
mammalian myocardium (rabbits, cats)
1-01 (SGYB) FRIEDMAN, MORTON H, THE JOHNS HOPKINS UNIVER-
SITY. JOHN HOPKINS ROAD. LAUREL. MARYLAND Correlation of arterial
hemodynamics and morphology (human).
.02 (SGYB) KARIC, lUCIJA STANCIC, PACIFIC MEDICAL CENTER.
POST OFFICE BOX 7999, SAN FRANCISCO. CALIF. Extracorporeal circu-
lation and protein denaturation (human).
-02 (CVB) KIRSCHENBAUM, MICHAEL A, UNIVERSITY OF CALIFOR
NIA. DEPARTMENT OF MEDICINE. LOS ANGELES. CALIF. Sodium
homeostasis and renal prostaglandins (dogs).
-02 (RAD) HARWIG, JOHN F, UNIV OF SOUTHERN CALIFORNIA. 1985
ZONAL AVENUE. LOS ANGELES, CALIF. Fibrinogen labeling with
radiometals.
.01 (CVB) SEALEY, JEAN E, CORNELL UNIVERSITY, 1300 YORK
AVENUE, NEW YORK, N Y. Prorenin-Physiological and biochemical
analysis (human).
.02 (RAD) OEUTSCH, EDWARD A, UNIVERSITY OF CINCINNATI. DE-
PARTMENT OF CHEMISTRY, CINCINNATI. OHIO. Development of 99-mTc
myocardial imaging agents.
-01 (CVA) POPP, RICHARD L, STANFORD UNIVERSITY. CARDIOLOGY
DIVISION. STANFORD. CALIF. Abnormal cardiac wall motion viewed ul-
trasonically (human, dogs, phantoms).
-02 (RAD) BARNDT. ROBERT, JR, UNIV OF SOUTHERN CALIFORNIA.
2025 ZONAL AVENUE. LOS ANGELES. CALIF. Angiographic estimation
of atherosclerotic wall thickness.
.01 (SSS) SENAY, LEO C, JR, ST LOUIS UNIVERSITY, 1402 SOUTH
GRAND. ST LOUIS. MO. Dynamics of interstitial space in whole
animals (rats).
-02 (CVB) GESELOWITZ, DAVID 8, PENNSYLVANIA STATE UNIVERSI-
TY. 328 HAMMOND BUILDING, UNIVERSITY PARK, PA. Simulation stu-
dies of the ECG in acute ischemia (and human).
.02 (CVB) TAN, SIANG Y, MEDICAL COLLEGE OF OHIO. DEPARTMENT
OF MEDICINE. TOLEDO. OHIO. Renin-mineralocorticoid axis in hyperten-
sive diabetics (human).
.01 (CVB) HOROWITZ, LEONARD N, UNIVERSITY OF PENNSYL-
VANIA. 3400 SPRUCE STREET. PHILADELPHIA, PA. Human ventricular
activation-Patterns and mechanisms (human).
-02 (SGYB) KIOSTER, FRANK E, UNIVERSITY OF OREGON. 3181 S W
SAM JACKSON PARK ROAD. PORTLAND. OREG. Randomized study of
coronary bypass surgery (human).
-02 (PHY) SACHS, FREDERICK, S U N Y - SCHOOL OF MEDICINE.
127 FARBER HALL. BUFFALO. N Y. Voltage clamp of isolated cardiac
Purkinje cells (dogs).
02 (CVA) SCHWARTZ, JEFFREY S, UNIVERSITY OF MINNESOTA,
BOX 194 MAYO MEMORIAL BLDG. MINNEAPOLIS. MINN. Coronary
vasomotion (dogs. pigs).
•02 (PBC) LAYMAN. DON I, UNIVERSITY OF OREGON. RESEARCH
BUILDING ROOM 416. PORTLAND. OREG. Collagen synthesis by cul-
tured human vascular cells.
01 (AFY) CROW, RICHARD S, UNIVERSITY OF MINNESOTA. UB OF
PHYSIOLOGICAL HYGIENE. MINNEAPOLIS. MINN Risk reduction and ex-
ercise fitness in a population
01 (CVB) NIES, ALAN S. UNIVERSITY OF COLORADO. DIV OF CLINI
CAL PHARMACOLOGY. DENVER. COLO Prostaglandins and local control
of the circulation (rats, dogs)
-01 (PHY) MAUGHAN, DAVID W, UNIVERSITY OF VERMONT. PHY &
BIOPHYSICS DEPARTMENT. BURLINGTON. VT. Sarcomere mechanics in
disrupted ventricular muscle (guinea pigs)
-02 (CVA) MARIN, MATTHEW G, UNIVERSITY OF ROCHESTER. 601
ELMWOOD AVENUE. ROCHESTER. N Y Respiratory tract secretion of
ions, water and mucus (human, dogs).
-02 (SSS) MIKLICH, DONALD R, NATIONAL ASTHMA CENTER, 1999
JULIAN STREET, DENVER, COLO. Mechanisms of emotions' asthma trig-
gering effect (human).
02 (SSS) VAN EGEREN, LAWRENCE F, MICHIGAN STATE UNIVERSI-
TY. A 227C EAST FEE HALL, EAST LANSING, MICH. Interpersonal stress
and coronary-prone behavior (human).
PROJECT NUMBER AND INVESTIGATOR ADDRESS
R23HI-2 1320-02 (PHRA) NEMECEK, GEORGINA M, UNIV OF MASSACHUSEHS
55 UKE AVENUE NORTH, WORCHESTER. MASS. Cyclic nucleotide
metabolism in vascular endothelium.
R01H1.2 1 323-02 (SSS) TAUB, EDWARD, INSTITUTE/BEHAVIORAL RESEARCH 2429
LINDEN UNE. SILVER SPRING. MD. Raynaud's disease and tempera-
ture self-regulation (human).
R23HL-21 325-02 (CVB) KRUEGER, JOHN W, ALBERT EINSTEIN COLLEGE OF MEO
1300 MORRIS PARK AVENUE, BRONX, N Y. Sarcomere kinematics in
cardiac contraction (rats, rabbits).
R23HL-2 1327-02 (PTHA) BOOR, PAUL J, UNIVERSITY OF TEXAS, PATHOLOGY DE-
PARTMENT, GALVESTON, TEX. Molecular mechanisms of chemical
myocardiopathies (rats).
R23HL-21 328-02 (PBC) OPPENHEIM, JOEL D, NEW YORK UNIVERSITY DEPART
MENT OF MICROBIOLOGY, NEW YORK, N Y. The I blood group antigen
of human erythrocyte membrane.
ROIHl-2 1329-02 (PHRA) VENTER, J CRAIG, S U N Y - AT BUFFALO. 122 CAPEN
HALL, BUFFALO, N Y. Beta-receptor regulation and cardiac sites of
drug action (cat, guinea pig, rat) .
R23HL-21 332-02 (CVB) lA lONE, BRIAN J, ARIZONA HEALTH SCIENCES CENTER
PHYSIOLOGY DEPARTMENT, TUCSON, ARIZ. Pulsatile regulation of flow
in the microcirculation (cats).
ROIHL-2 1342-02 (CVA) BARR, UOYD, UNIVERSITY OF ILLINOIS. 524 BURRILL
HALL, URBANA, ILL. Isolation and analysis of sodium channel from
heart (frogs).
R23HI-21347-02 (SGYB) PRITCHETT, EDWARD I, DUKE UNIVERSITY, BOX 3477,
DURHAM, N C. Accessory pathways and supraventricular tachycardia
R01H1.213S1-02 (CVB) WEEMS, WILLIAM A, UNIVERSITY OF TEXAS, POST OFFICE
BOX 20708, HOUSTON, TEX. Renal and vascular control by sym-
pathetic ganglia (animals).
ROlHL-21 352-02 (EDC) BOUHUYS, AREND, YALE UNIVERSITY, 333 CEDAR
STREET, NEW HAVEN, CONN. Community studies of obstructive lung
disease (human).
R01HL-21 367-02 (MCHA) IRELAND, ROBERT E, CALIFORNIA INST OF TECHNOLO
GY, DIV OF CHEM & CHEM ENG 164-30 , PASADENA, CALIF. Polyether
lonophores -Synthesis of X537A and analogs.
R23HL-21368-02 (CVA) DANILO, PETER, JR, COLL OF PHYSICIANS & SURGEONS
DEPARTMENT OF PHARMACOLOGY, NEW YORK. N Y. Perinatal cardiac
electrophysiology (dogs).
R23HL-2 1369-02 (PTHA) CLARK, JEFFREY N, OAK RIDGE NATIONAL LABORATORY
POST OFFICE BOX Y, OAK RIDGE, TENN. Tracheal mucin synthesis in
experimental bronchitis (rats).
ROIHL-2 137 1-02 (MCHB) JOHNSON, DALE E, UNIVERSITY OF WASHINGTON
CENTER FOR BIOENGINEERING, SEAHLE, WASH Energy loss microanal-
ysis of myocardial cations.
ROIHL-2 1376-02 (CVA) WANGENSTEEN, O DOUGLAS, UNIVERSITY OF MIN-
NESOTA, 435 DEUWARE ST, S E, MINNEAPOLIS, MINN. Blood-gas barri-
er solute and water transport (rabbits).
ROIHl-21379-01 (HEM) MARDER, VICTOR J, UNIVERSITY OF ROCHESTER 601
ELMWOOD AVENUE, ROCHESTER, N Y. Structure of factor Vlll-Von Wil-
lebrand protein (human).
R01HL-21381-02 (MET) TAEGTMEYER, HEINRICH, PETER BENT BRIGHAM
HOSPITAL, 721 HUNTINGTON AVENUE, BOSTON, MASS. Amino acid
metabolism in normal and hypoxic myocardium (rabbits).
R23HL-2 1382-02 (CVB) GOTSHALl, ROBERT W, WRIGHT STATE UNIVERSITY. BOX
927, DAYTON, OHIO. Effect of pressure on renal blood flow and func-
tion (dogs).
R23HL-21393-01 (CVA) WHITMAN, VICTOR, PENNSYLVANIA STATE UNIVERSITY
MILTON S HERSHEY MEDICAL CTR, HERSHEY. PA. Cardiac adaptation
to aging and stress (rats).
ROIHL-2 1394-02 (PC) SOFFER, RICHARD I, CORNELL UNIVERSITY DEPT OF
MEDICINE & BIOCHEM, NEW YORK, N Y. Pulmonary angiotensin-con-
verting enzyme (rabbits).
R23HI-2 1396-02 (PTHA) PICCIANO, PAUL T, ALBERT EINSTEIN COLLEGE OF MED,
DEPT, BRONX, NY. Isolation, growth and metabolism of type I pneu-
mocytes (rabbits).
ROIHl-2 1403-02 (HEM) SHUMAN, MARC A, UNIVERSITY OF CALIFORNIA 1282
MOFFITT HOSPITAL, SAN FRANCISCO, CALIF. Blood clotting kinetics stu-
died by radioimmunoassay (human).
ROIHL-2 1404-01 (BBCB) KAUFFMAN, JOHN W, NORTHWESTERN UNIVERSITY
THE TECHNOLOGICAL INSTITUTE. EVANSTON, ILL. Raman spectroscopy
of erythrocyte and model membranes (human).
R23HL-2I405-01 (HED) STARK, ANN R, BOSTON HOSPITAL FOR WOMEN 221
LONGWOOD AVENUE, BOSTON, MASS. Respiratory muscles in regula-
tion of infant breathing (human).
R23HL-2 1409-02 (HED) CLYMAN, RONALD I, UNIVERSITY OF CALIFORNIA PAR-
NASSUS AVENUE. SAN FRANCISCO, CALIF. Perinatal control of the duc-
tus arteriosus (sheep).
R23HL-2141I-02 (PBC) SCHLESINGER, PAUL H, WASHINGTON UNIVERSITY 660
SOUTH EUCLID, ST LOUIS, MO. Control of extracellular lysosomal
hydrolase levels (rats).
R23HL-21413-02 (PBC) MC GOWAN, ELEANOR B, S U N Y DOWNSTATE MEDI
CAL CTR, 450 CURKSON AVENUE, BROOKLYN, N Y Structure and
function of platelet calcium-binding protein (human).
ROIHl-2 141 6-02 (PTHA) HUNT, CHARLES, UNIVERSITY OF ALABAMA, UNIVERSITY
STATION, BIRMINGHAM, ALA Atherosclerosis in new modles of
diabetes mellitus
ROIHL-21418-02 (CVB) WEXLER, BERNARD C, MAY INSTITUTE FOR MEDICAL
RES, 421 RIDGEWAY AVENUE. CINCINNATI, OHIO Experimental myocar
dial inlarction (rats)
R23HI-2142I-0I (BIO) WEBER, HERBERT, ALBERT EINSTEIN COLL OF MED. 1300
MORRIS PARK AVENUE. BRONX. N Y Myocardial and vascular conlrac
tility and cyclic nucleotides (cattle, rats)
■0IHL-2I42S-02 (CVB) MC MAHON, THOMAS A, HARVARD UNIVERSITY, 29 OX
FORD STREEI. CAMBRIDGE. MASS Servo simulated compliance
changes A reversible Ml (dogs)
UIHl-31426-02 (SSS) ERICKSON, JAMES R, UNIVERSITY OF TEXAS DEPART
MENT OF PSYCHOLOGY. ARLINGTON, TEX Learned heart rale control
(human)
ROIHl-31427-02 (SSS) FRIEDMAN, MEYER, POST OFFICE BOX 7921, SAN FRAN-
CISCO, CALIF. Behavioral changes in post infarction patients.
R33HI-2 1 438-02 (HEM) ORKIN, STUART H, CHILDREN'S HOSPITAL MED CENTER
300 LONGWOOD AVENUE, BOSTON. MASS. Expression of human globin
in thalassemia (human).
574
R01HL-21429-02 (PTHA) COLTON, CLARK K, MASSACHUSEHS INST OF TECH
DEPT OF CHEMICAL ENGINEERING. CAMBRIDGE, MASS. Transport of
LDL in arterial wall (human, mammals).
R01HL-21431-02 (HEM) CORRIGAN, JAMES J, JR, UNIVERSITY OF ARIZONA DE-
PARTMENT OF PEDIATRICS. TUCSON, ARIZ. Factor II antigen and
coagulant activity (human, animals).
R23HL-2 1434-02 (PHY) STOWE, DAVID F, MEDICAL COLL OF WISCONSIN 561
NORTH 15TH STREET, MILWAUKEE, WIS. Intrinsic control of coronary
blood flow by chemicals (guinea pigs).
R01HL-21435-02 (CVB) YOUNG, DAVID B, UNIVERSITY OF MISSISSIPPI 2500
NORTH STATE STREET, JACKSON, MISS. Control, cardiovascular and
renal effects of potassium (dogs).
ROIHL-2 1436-02 (CVB) WEAVER, LYNNE C, MICHIGAN STATE UNIVERSITY DE-
PARTMENT OF PHYSIOLOGY, EAST UNSING. MICH. Autonomic control
of renal function (cats).
R01HL-21438-02 (PTHA) GERRITY, ROSS G, CLEVEUND CLINIC FOUNDATION
9500 EUCLID AVENUE, CLEVELAND, OHIO. Structure and permeability
of arterial endothelium (pigs).
R01HL-21444-02 (CVA) MOTOYAMA, ETSURO K, YALE UNIVERSITY, 333 CEDAR
STREET, NEW HAVEN, CONN. Pulmonary mechanics during postnatal
development (human).
R01HL-2I45I-01 (AFY) PROPPE, DUANE W, UNIVERSITY OF TEXAS, 7703 FLOYD
CURL DRIVE, SAN ANTONIO, TEX. Control of circulation during heat
stress and (ever (baboon).
ROIHL-2 1452-02 (CVA) SPATH, JAMES A, JR, JEFFERSON MEDICAL COLLEGE
1020 LOCUST STREET, PHILADELPHIA, PA. Pulmonary capillary filtra-
tion in myocardial ishemia (dogs).
ROlHL-21457-01 (SSS) FULLERTON, DWIGHT S, OREGON STATE UNIVERSITY
SCHOOL OF PHARMACY, CORVALLIS, OREG. C(17)-side group geometry
and cardenolide activity (cats, guinea pigs).
R01HL-21460-02 (SSS) LEES, ROBERT S, MASSACHUSEHS INST OF TECH. 40 AMES
STREET, CAMBRIDGE, MASS. Lipoproteins, hemostasis and atheros-
clerosis (human, rabbits).
R01HL-2146I-01 (MCHB) MC LENDON, GEORGE L, UNIVERSITY OF ROCHESTER
DEPARTMENT OF CHEMISTRY, ROCHESTER, N Y. Heme group protein
interactions in hemoproteins.
R23HL-2 1 462-02 (CVB) CAMPBELL, KENNETH B, WASHINGTON STATE UNIVERSI
TY. COLLEGE OF VETERINARY MEDICINE. PULLMAN. WASH. Mechanical
interactions between ventricle arteries (dogs).
R01HL-21469-01 (HEM) LEE, KWANG S, S U N Y AT DOWNSTATE. 450 CURKSON
AVENUE. BROOKLYN. N Y. Active transport and effect of CAOO in
sickle cell (human).
R01HL-21471-02 (PC) ELZINGA, MARSHALL, BROOKHAVEN NATL LABORATORY
BIOLOGY DEPARTMENT. UPTON. N Y. Structure-function studies on
actio and myosin (human, protozoa, rabbits, cattle).
ROIHl-21476-02 (PHRA) FEIDMAN, STUART, UNIVERSITY OF HOUSTON 4800
CALHOUN BLVD. HOUSTON, TEX. Anticoagulant drug absorption in-
teractions (rats).
R01HL-2I480-01 (PBC) LYNN, WILLIAM S, DUKE UNIVERSITY, POST OFFICE BOX
3711, DURHAM, N C. Structure, source and (unctions of alveolar
glycoproteins (human, rabbits).
R01HL-21482-01 (CVA) SCHEUER, JAMES, MONTEFIORE HOSP & MED CENTER
111 EAST 210TH STREET, BRONX. N Y. Cardiac function and metabol-
ism in diabetes (rats).
R01HL-21483-01 (BBCA) SZABO, ATTILA, INDIANA UNIVERSITY, DEPARTMENT OF
CHEMISTRY, BLOOMINGTON, IND. Electronic, thermodynamic and
kinetics of hemoglobin.
ROIHL-2 1487-01 (HEM) PHILLIPS, DAVID R, ST JUDE CHILDREN'S RES HOSP 332
N LAUDERDALE, MEMPHIS. TENN. Molecular characterization of (jlanz-
mann's thrombasthenia (human).
R23HI-2 1488-0 1 (PBC) STAFFORD, WAITER F, III, BRANDEIS UNIVERSITY. SOUTH
STREET. WALTHAM. MASS. Myosin-linked regulation in vertebrate
smooth muscle (calf aorta).
R23HL-2 1490-02 (HEM) SILK, SUSAN T, N Y HOSP-CORNELL MEDICAL CTR 525
EAST 68TH STREET. NEW YORK, N Y. Studies of enzymes in human
platelet membranes.
R01HL-21493-02 (CVB) PANG, DAVID C, VIRGINIA COMMONWEALTH UNIV MEDI-
CAL COLLEGE OF VIRGINIA, RICHMOND, VA. Contractility in cardiac
failure (hamsters).
ROIHl-21498-02 (CVB) GRANGER, HARRIS J, TEXAS ASM UNIVERSITY DE-
PARTMENT OF PHYSIOLOGY, COLLEGE STATION. TEX. Pathophysiology
of edema (rats, cats).
ROIHL-2 1500-02 (CVA) ROCHESTER, DUDLEY F, UNIVERSITY OF VIRGINIA
SCHOOL OF MEDICINE, CHARLOHESVILLE, VA. Performance of respira-
tory muscles under stress (dogs).
R23HI-2 1504-02 (PBC) KELLEY, JASON, UNIVERSITY OF VERMONT, COLLEGE OF
MEDICINE, BURLINGTON, VT. Collagen synthesis in pulmonary fibrosis
cells (human).
R01HL-21513-02 (NTN) HOLMAN, RALPH T, UNIVERSITY OF MINNESOTA 801
16TH AVENUE N E, AUSTIN. MINN. Metabolism of trans fatty 'acids
(human, rats, swine).
R01HL-21518-01 (CVA) MITCHELL, RICHARD R, INSTITUTES OF MEDICAL SCIS
POST OFFICE BOX 7999, SAN FRANCISCO. CALIF. Improvement in re-
gional ventilation-pertusion resolution (human).
ROIHL-2 1523-01 (CVB) SULLIVAN, JAY M, 951 COURT AVENUE. MEMPHIS. TENN.
Hemodynamic effects of dietary sodium in man.
ROIH1.2IS25-02 (CVB) HADDY, FRANCIS J, UNIFORMED SERVS UNIV/HLTH SCIS
4301 JONES BRIDGE ROAD. BETHESDA. MD Effect of cations, anions
and water upon blood vessels (dogs, rats)
R01HL-21527-01 (EOC) RAHIMTOOLA, SHAHBUOIN H, UNIVERSITY OF
OREGON, 3181 SW SAM JACKSON PARK ROAD , PORTLAND. OREG,
Prospective study of bundle branch block (human).
ROIHl-21532-02 (SSS) MILLER, NEAL E, ROCKEFELLER UNIVERSITY. 1230 YORK
AVENUE, NEW YORK, N Y Cardiovascular homeostasis and learning
(frogs, rats, human).
ROIHL-2 1533-02 (SGYB) CHESEBRO, JAMES H, MAYO FOUNDATION, 200 FIRST
STREET SOUTHWEST, ROCHESTER, MINN Platelet inhibitor drug in
coronary surgery (human)
R23HI-21S39-02 (CVA) EVANS, JOHN N, UNIVERSITY OF VERMONT, PHYSIOLOGY
& BIOPHYSICS DEPT, BURLINGTON, VT. Mechanical properties of iso-
lated small bronchioles (rabbits)
ROIHl-2 1540-02 (PC) GERATZ, J DIETER, UNIVERSITY OF NORTH CAROLINA, DE-
PARTMENT OF PATHOLOGY, CHAPEL HILL, N C. Specific inhibitors of
coagulation and fibrinolysis (rats, rabbits, dogs).
■0IHl-aiS43
R01HL-atS44
R01HI-21S48-
R23HI-2ISS9
R01HI-21S6S-
R01HL-21S6B
R01HL-3IS70-
ROIHl-21577-
R0)HL-21S74
R01HL-21S78
P01HL-21S84
P01HL-21584
POIHL-2IS84-
POIHI-21S84
P01Hl-2ISe4
P01HL-21584-
roiHL-21S84
raiHL-21584
P01HL-21584
R0IHL-21S89-
R01HL-21S92-
R01HL-21612
R01HL-2161S'
ROlHl-21617
R01HL-21622
ROIHl-21626
R01HL-2I628
ROIHl-21632
ROIHl-21641
R01HL-21644
R01HL-2I646
ROIHl-21649
R0IHL-2I6S4
ROIHl-21657
R23HI-21663-
575
.02 (HIM) »URII, 8RUCI. NEW ENGLAND MfDICAl CTR HOSP, 1/1
HARRISON AVENUE, BOSTON. MASS SUuctuie lunction teialion o(
blood clotting ptoleins (labbits)
-02 (HIM) ORIfflN. JOHN H. SCRIPPS CLINIC & RESEARCH EON.
10666 NORIH lORRLY PINfS ROAD . LA JOLLA. CALIF Proteins ol
coagulation snil llagcnidn lacloi pathways (human, goats)
01 (PTHA) OUREWICH, VICTOR, ST ELIZABETHS HOSPITAL. 736
CAMBRIDGE STREET. BOSTON. MASS Pathogenesis ol pulmonaiy
thromboembolic disease (human, mammals)
.01 (CVA) SCHNEIDERMAN. GARY, MASSACHUSETTS INST OF
TECH. ;? MASSACHUSETTS AVENUE, CAMBRIDGE. MASS Oxygen
supply and blood (low through aortic vasa vasorum (dogs)
■02 (PTHA) HENSON, PETER M, NATIONAL lEWISH HOSPITAL. 3800 E
COLFAX AVENUE. DENVER. COLO Pathogenesis ol inflammatory lung
iniury (lats. labbits)
02 (CVA) RYAN, UNA S, UNIVERSITY OF MIAMI. P 0 BOX S2087S.
BISCAYNE ANNEX. MIAMI, FU Cell biology of the alveolar capillary
unit (animals)
01 (CVA) COOPER, GEORGE, IV, UNIVERSITY OF IOWA. DEPT OF
INTERNAL MEDICINE. IOWA CITY. IOWA. The mechanical basis ol
myocardial energetics (cats)
01 (SGYB) STRANONESS, DONALD E, JR, UNIVERSITY OF
WASHINGTON, DEPARTMENT OF SURGERY, SEATTLE. WASH. Natural his
tory of the postphlebitic syndrome
■01 (CVB) TSE, WARREN W, UNIVERSITY OF HEALTH SCIENCES.
2020 WEST OGDEN STREET, CHICAGO. ILL. Automaticity ol AV node
and Its adjacent tissues (dogs)
.01 (AFY) GOIDRING, DAVID. ST LOUIS CHILDREN'S HOSPITAL, 500
S KINGSHIGHWAY BOULEVARD. ST LOUIS. MO. Effect of exercise upon
the hypertensive adolescent
.02 (HIBA) HYATT, ROBERT E, MAYO FOUNDATION. 200 FIRST
STREET SOUTHWEST. ROCHESTER. MINN Respiratonf mechanics in
normal and abnormal states
-02 0001 (HIBA) WIISON, THEODORE A. RespiratorT) mechanics
in normal and abnormal states ■Engineering analysis of lung deforma-
tion (human, animals),
.02 0002 (HLBA) RODARATE, JOSEPH R. Respiratory mechanics
in normal and abnormal states-Lung mechanics -Regional deforma-
tion and ventilation (dogs)
•02 0003 (HIBA) REHDER. KAI. Respiratory mechanics in normal
and abnormal states -Effects of anesthesia on ventilation and respira-
tory mechanics in man.
.02 0004 (HLBA) HYATT, ROBERT E. Respiratory mechanics in nor
mal and abnormal states-Effects of anesthesia on respiratory
mechanics (dogs).
-02 0005 (HLBA) RUSSELL, JAMES A. Respiratory mechanics in
normal and abnormal states -Regulation, and behavior of airway
smooth muscle (human, animals).
.02 0006 (HLBA) HYATT, ROBERT E. Respiratory mechanics in nor-
mal and abnormal states -Respiratory mechanics in health and dis-
ease (human, pigs).
02 9001 (HLBA) LAI-FOOK, STEPHEN J. Respiratory mechanics in
normal and abnormal states -Technical and equipment core.
.02 9002 (HLBA) CHEVALIER, PETER A. Respiratory mechanics in
normal and abnormal states-Computational and statistical core facili-
ty
.01 (RAD) ALS, ANN V, HARVARD MEDICAL SCHOOL. 330 BROOKLINE
AVENUE. BOSTON. MA. Radiographic contrast toxicity in ischemic
.01*(PTHA) KOTTKE, BRUCE A, MAYO FOUNDATION, 200 FIRST
STREET. S W. ROCHESTER. MINN. Lipoproteins and coagulation factors
in atherosclerosis (pigeons).
.02 (SRC) OEGEMA, THEODORE R, UNIVERSITY OF MINNESOTA,
412 UNION STREET SOUTHEAST. MINNEAPOLIS. MINN. Biochemistry of
lung proteoglycans (human, rabbits).
-01 (PBC) WEISSMANN, BERNARD, UNIVERSITY OF ILLINOIS. 835
SOUTH WOLCOTT STREET, CHICAGO. ILL. Structural studies of lung
hcparinoid polysaccharides (cattle).
.02 (SRC) EHRLICH, KENNETH C, GULF SOUTH RESEARCH IN
STITUTE. POST OFFICE BOX 26500. NEW ORLEANS, LA. Biochemistry of
lung proteoglycans (rabbits, cattle).
-02 (SRC) BLACKWELl, JOHN, CASE WESTERN RESERVE UNIV, DEPT
OF MACROMOLECULAR SCIENCE. CLEVEUND. OHIO. Structure and in-
teractions of lung proteoglycans (cattle).
-01 (SRC) PEDRINI, VITTORIO A, UNIVERSITY OF IOWA, DEPART-
MENT OF ORTHOPAEDIC SURG. IOWA CITY, IOWA. Proteoglycans of
animal lung parenchyma (cattle, pigs, rabbits).
02 (PC) FAIRCLOUGH, GORDON F, JR, CORNELL UNIVERSITY.
1300 YORK AVENUE, NEW YORK, N Y. Biosynthesis of lung surfactant
lipid (rabbit)
-02 (SGYA) BRUESCHKE, ERICH E, RUSH PRESBY ST LUKES MED
CTR, WEST CONGRESS PARKWAY, CHICAGO, IL. Development of a
transcutaneous povier transfer system (cattle)
02 (SRC) MASHBURN, THOMPSON A, JR, UNIVERSITY OF TEN
NESSEE, 894 UNION AVENUE. MEMPHIS. TENN. Structural studies of
lung proteoglycans (pigs, cattle, rabbits).
-01 (PBC) MOSHER, DEANE F, JR, UNIVERSITY OF WISCONSIN. 1300
UNIVERSITY AVENUE. MADISON. WIS Fibronectin and related
glycoproteins (human, rodents).
■02 (SRC) O'BRIEN, JOHN F, UNIVERSITY OF WISCONSIN. 2605
MARSH LANE. MADISON. Wl Biosynthesis of fractionated proteoglycans
ol lung (rabbits)
•01 (SRC) RADHAKRISHNAMURTHY, BHANDARU, LOUISIANA
STATE UNIVERSITY. 1542 TULANE AVENUE. NEW ORLEANS. LA
Biochemistry of lung proteoglycans (mammals)
1-01 (CVB) CORR, PETER B, WASHINGTON UNIVERSITY. 660 SOUTH
EUCLID. ST LOUIS. MO Autonomic determinants of arrhythmia due to
ischemia (cats)
■01 (CVA) DOWNEY, H FRED, METHODIST HOSPITAL. POST OFFICE
BOX 5999, DALLAS. TEX. Regional nonischemic myocardial hypoxia
(dogs).
,01 (PBC) PAWLOWSKI, PHILIP J, WESLEYAN UNIVERSITY. DEPART-
MENT OF BIOLOGY, MIDOLETOWN, CONN. Regulation of collagen
biosynthesis (chick, embryo).
R01H1.2I66S
ROIHL-21670
R01HL.21672
R01HL-21673
R01HL-21674
R01HL-21676-
R01HL-21683
R01HL-21684
R01HL-21684-
R01HL-21684-
R01HL
ROIHL
21684
-21684
R01HL-21684-
R01HL-21686
R01HL-21690
R01HL-
R01HL.
ROIHL
ROIHL
21692
•21697
21701
-21706
R01HL-2I707
R01HL-21710
R01HL-21719
R23HL-21730-
R01HL-2I73S-
R01HL-21742-<
R01HL-217S0
R01HL-217S1
R01HL-21751
R01HL-
R01HL
ROIHL
R01HL-21757
R01HL-21763
R01HL-21764
R01HL-21769
R01HL-21779
PROJECT NUMBER AND INVESTIGATOR ADDRESS
01 (PBC) MAYNE. RICHARD. UNIVERSITY Of ALABAMA. UNIVIRSIIY
STATION, BRIMINGHAM, AlA Coll»g«n polymorphism »nd •rternl
structure (monkeys, guinea pigs)
.01 (PHRA) RAHWAN, RALF O, OHIO SIATE UNIVERSITY. 500 W
l?TH AVENUE. COLUMBUS, OHIO Antiarrhythmic sludm on 2 sub
slituled aminoindenes (dogs)
.01 (PHRA) HONOEGHIM, LUC M, UNIVERSITY OF CALIfORNIA, OE
PARTMENI OF PHARMACOLOGY, SAN FRANCISCO. CA Antiarrhythmic
diug action on VMA/ of cardiac cells
-01 (CVB) SIMON, OEZA, VETERANS ADMINISTRATION HOSP. 54IH
STREET AND 48TH AVENUE S . MINNEAPOLIS. MINN Pathophysiology of
venous changes in hypertension (rats, rabbits, human, dogs)
01 (SGYB) SCHUDER, JOHN C, UNIVERSITY OF MISSOURI. DEPART
MENT OF SURGERY. COLUMBIA. MO Development of automatic im-
planted defibrillator (dogs, cattle)
■02 (SRC) GOLDWASSER. EUGENE, CUMMINGS LIFE SCIENCE
CENTER. 920 EAST 58TH STREET. CHICAGO. ILL Purification and pro
perties of erythropoietin (human)
■02 (SRC) LEE-HUANG, SYLVIA, NEW YORK UNIVERSITY MEO CTR.
550 FIRST AVENUE. NEW YORK. N Y Purification of erythropoietin
-02 (SRC) ALONSO, DANIEL R, CORNELL UNIVERSITY. 1300 YORK
AVENUE. NEW YORK, N Y Radionuclide infarct sizing and therapy
evaluation
02 0001 (SRC) JACOBSTEIN, JEROME G. Radionuclide infarct
sizing and therapy evaluation Evaluating preservation of ischemic
myocardium by radioisotope methods (dog)
02 0002 (SRC) ALONSO, DANIEL R. Radionuclide infarct sizing
and therapy evaluation -Evaluating myocardial imaging agents in
global and regional ischemia (rabbits)
02 0003 (SRC) ALONSO, DANIEL R. Radionuclide infarct sizing
and therapy evaluation-Core pathology laboratory (dogs, human)
•02 0004 (SRC) CAHILL, PATRICK T. Radionuclide infarct sizing
and therapy evaluation -Image analysis-Kinetics of infarction, ven-
tricular function (human, animal).
.02 0005 (SRC) SCHEIDT, STEPHEN. Radionuclide infarct sizing
and therapy evaluation-Clinical evaluation of radioisotope imaging
methods for quantifying infarct size
,02 (SRC) DIXON, JONATHAN S, UNIVERSITY OF CALIFORNIA.
UWRENCE BERKELEY LABORATORY, BERKELEY, CALIF Purification of
erythropoietin (human).
.02 (SRC) ZARET, BARRY L, YALE UNIVERSITY. 333 CEDAR STREET.
87 LMP, NEW HAVEN. CONN. Sequential multinuclide study of acute
infarction (human, dogs).
-02 (SRC) SPIVAK, JERRY L, JOHNS HOPKINS UNIVERSITY, 720 RUT-
LAND AVENUE. BALTIMORE. MD. Purification of erythropoietin (human)
-01 (SRC) BUDINGER, THOMAS F, UNIVERSITY OF CALIFORNIA,
LAWRENCE BERKELEY LABORATORY, BERKELEY, CALIF. Myocardium in-
farct sizing by 82Rb emission tomography (dogs, human)
-02 (SRC) FISHER, JAMES W, TULANE UNIVERSITY. 1430 TULANE
AVENUE. NEW ORLEANS, LA. Purification of erythropoietin (human).
02 (SRC) KAPLAN, JEROME I, INDIANA UNIVERSITY, 1201 EAST
38TH STREET. INDIANAPOLIS, IND. Nuclear magnetic resonance and
myocardial ischemia (rats).
.01 (SRC) KEYES, JOHN W, JR, UNIVERSITY HOSPITAL, 1405 E ANN
STREET, ANN ARBOR. MICH. Quantification of infarct size by emission
tomography (human, dogs).
-01 (SRC) BURGESS, MARY J, UNIVERSITY OF UTAH, INTERNAL
MEDICINE DEPARTMENT. SALT LAKE CITY, UTAH. Electrocardiographic
methods of quantifying infarct size (human, dogs).
-01 (SRC) ADAMS, DOUGLASS F, PETER BENT BRIGHAM HOSPITAL.
721 HUNTINGTON AVENUE. BOSTON, MASS. Computed cardiac tomog-
raphy in infarct sizing (dogs, human).
01 (HEM) MONTGOMERY, ROBERT R, JR, UNIVERSITY OF
COLORADO, 4200 EAST NINTH AVENUE, DENVER. COLO. vWagll-A new
vWD deficient antigen (human).
.01 (CVA) MYERBURG, ROBERT J, UNIVERSITY OF MIAMI, POB
520875. BISCAYNE ANNEX. MIAMI. FLA. Electrophysiology after healed
myocardial infarction (cats).
-01 (PHRA) COURTNEY, KENNETH R, STANFORD RESEARCH IN
STITUTE, 333 RAVENSWOOD AVENUE, MENLO PARK. CALIF. Frequency-
dependent drug actions in cardiac muscle (rabbits).
-02 (SRC) REICHENBACH, DENNIS D, UNIVERSITY OF WASHING-
TON, DEPARTMENT OF PATHOLOGY, SEATTLE, WASH. Electrocardio-
graphic quantification of infarct size (dogs, human).
-02 (SRC) POHOST, GERALD M, MASSACHUSETTS GENERAL
HOSPITAL, CARDIAC UNIT 32 FRUIT STREET, BOSTON, MASS. Thallium
and antimyosin in ischemia and infarction.
-02 0001 (SRC) INGWALL, JOANNE S. Thallium and antimyosin
in ischemia and infarction-ln vitro models of ischemia and infarction
(rats. mice).
-02 0002 (SRC) BELLER, GEORGE A. Thallium and antimyosin in
ischemia and infarction -Canine models of ischemia and infarction.
02 0003 (SRC) POHOST, GERALD M. Thallium and antimyosin in
ischemia and infarction-Human studies-Ischemia and infarction.
.11 (PTHA) GOLDFISCHER, SIDNEY L, ALBERT EINSTEIN COLLEGE
OF MEO. 1300 MORRIS PARK AVENUE. BRONX. N Y. Vascular disease-
Cytochemistry and ultrastructure (human, rats. mice, hamsters) .
-01 (BBCB) ENGLANDER, S WALTER, UNIVERSITY OF PENNSYL-
VANIA. BIOCHEMISTRY & BIOPHYSICS DEPT. PHILADELPHIA. PA Elastin
structure-DNA breathing -Hemoglobin S gelation
i.09 (PBC) CONRAD, H EDWARD, UNIVERSITY OF ILLINOIS.
BIOCHEMISTRY DEPARTMENT. URBANA. ILL Heparin and heparan
sulfate -Structure and activity (beef, hog)
.01 (MCHB) PRIVETT, ORVILLE S, UNIVERSITY OF MINNESOTA. 801
16TH AVENUE N E. AUSTIN, TEX Ultramicroanalysis of prostaglandins
and related compounds (rats)
.01 (MCHA) LEE, WILLIAM W, STANFORD RESEARCH INSTITUTE, 333
RAVENSWOOD AVENUE, MENLO, PARK CALIF. Blood compatible
benzamidine containing polymers.
-01 (CVB) GOMEZ-SANCHEZ, CELSO E, DEPT OF INTERNAL
MEDICINE. 5323 HARRY HINES BLVD. DALLAS. TEX. Steroids in adrenal
regeneration hypertension (rats).
21751
21751
•21756
PROJECT NUMBER AND INVESTIGATOR ADDRESS
R23HL.21 783-01 (CVA) RAU, ERIC E, UNIVERSITY OF CALIFORNIA, CTR/HEALTH
SCIENCES, LOS ANGELES, CALIF. Ionic control of contractility in anoxic
myocardium (rabbits, rats).
■01 (COM) CLAYTON, PAUL D, LDS HOSPITAL, 325 8TH AVENUE,
SALT LAKE CITY, UTAH. Left ventricular wall motion analysis
■01 (SGYB) COHN, LAWRENCE H, PETER BENT BRIGHAM
HOSPITAL, 721 HUNTINGTON AVENUE, BOSTON, MASS. Long-term ef-
fects of myocardial protection (dogs, rats).
-01 (BBCA) INGHAM, KENNETH C, AMERICAN NATIONAL RED
CROSS, 9312 OLD GEORGETOWN ROAD, BETHESOA, MO, Precipitation
of proteins with poly (ethylene glycol) (human).
-02 (SRC) PARMLEY, WILLIAM W, UNIVERSITY OF CALIFORNIA
1186-MOFFITT HOSPITAL, SAN FRANCISCO, CALIF. Functional infarct
size by gated radioangiography (human, dogs).
-01 (SGYB) lOGERFO, FRANK W, UNIVERSITY HOSPITAL 75 EAST
NEWTON STREET, D517, BOSTON, MASS. Applied pulsatile hemodynam-
ics in vascular surgery (dogs).
-01 (PHRA) SIMPSON, JOHN B, UNIVERSITY OF WASHINGTON
PSYCHOLOGY DEPARTMENT, SEAHLE, WASH. Circumventricular sites of
pressor action of angiotensin II (rats).
•01 (PHRA) SIMPSON, JOHN B, UNIVERSITY OF WASHINGTON DEPT
OF PSYCHOLOGY NI-25, SEAHLE, WASH Angiotensin effects on' water
intake and excretion.
01 (SGYB) ROSEN, JONATHAN J, UNIVERSITY OF WASHINGTON
DEPT OF CHEM ENGR, BF-10, SEAHLE. WASH. Tissue cell interactions
with vascular prostheses (human, rats, mice).
-02 (CVA) KATZ, ARNOLD M, UNIVERSITY OF CONNECTICUT,
FARMINGTON, CONN. Actions of drugs and ions on cardiac membranes
(rabbits, guinea pigs).
-01 (PHRA) ZIEGLER, MICHAEL G, UNIVERSITY OF TEXAS, PHARM &
TOX DEPARTMENT, GALVESTON, TEX. Catecholamines, blood pressure
and circulation.
-01 (CVB) MASON, DEAN T, UNIVERSITY OF CALIFORNIA, SCHOOL
OF MEDICINE, DAVIS, CALIF, Regulatory role of myosin in cardiac
hypertrophy (dogs).
•01 (PTHA) OGRA, PEARAY L, CHILDREN'S HOSPITAL, 219 BRYANT
STREET, BUFFALO, N Y. Etiology of obstructive airway disease in chil-
dren (also monkeys).
■05 (PC) SALSER, WINSTON A, UNIVERSITY OF CALIFORNIA 405
HILGARD AVENUE, LOS ANGELES, CALIF. Determining sequences from
hemoglobin messenger RNA (mice, chickens, rabbits).
01 (CVA) WHITFIELD, CAROL F, MILTON S HERSHEY MED CENTER
500 UNIVERSITY DRIVE, HERSHEY, PA. Control of sugar entry in nor-
mal and diabetic heart (rats).
01 (CVB) DEGIROLAMI, UMBERTO, UNIVERSITY OF MAS
SACHUSEHS, 55 UKE AVENUE NORTH, WORCESTER, MASS. Ischemia,
diabetes and the microcirculation (rats, cats, hamsters)
•01 (CTY) YU, JOHN C, SCRIPPS CLINIC & RES FDN, 10666 NORTH
TORREY PINES ROAD , LA JOLU, CALIF. Human red cell membrane -
Structure and function.
■01 (SSS) REVESZ, GEORGE, TEMPLE UNIVERSITY, 3400 NORTH
BROAD STREET, PHILADELPHIA, PA. Cardiac failure defection by
radiography and optics (monkeys).
•02 (GMB) AL-AWQATI, QAIS, COLUMBIA UNIVERSITY, DEPARTMENT
OF MEDICINE, NEW YORK, N Y Control of sodium transport and cellu-
lar respiration (toad bladder).
■01 (CVB) LIMAS, CONSTANTINOS J, UNIVERSITY OF MINNESOTA
BOX 83 - MAYO MEMORIAL BLDG, MINNEAPOLIS, MINN. Calcium trans-
port in the hypertrophied myocardium (rats, animals)
•01 (CVB) KONTOS, HERMES A, MEDICAL COLLEGE OF VIRGINIA
DEPARTMENT OF MEDICINE, RICHMOND, VA. Cerebral microcirculation
in experimental hypertension (cats, rabbits).
•01 (CVA) YOUNG, STEPHEN L, DUKE UNIVERSITY, DURHAM, N C.
Lung metabolism and alveolo-capillary permeability (rats).
•01 (COM) FELDMAN, HENRY A, HARVARD UNIVERSITY 665
HUNTINGTON AVENUE, BOSTON, MASS. Mathematical models of
branching in the human lung.
01 (SGYB) DEWEY, C FORBES, JR, MASSACHUSEHS INST OF TECH
ROOM 3-250, CAMBRIDGE, MASS. Unsteady flow in arterial bifurca-
tions (human).
-18 (PHRA) FURCHGOTT, ROBERT F, S U N Y - DOWNSTATE MED
CENTER, 450 CURKSON AVENUE, BROOKLYN, N Y. Factors influencing
responses to adrenergic drugs (guinea pigs, rats, cats)
-01 (CVA) BACHE, ROBERT J, UNIVERSITYO F MINNESOTA, BOX 338
MAYO BUILDING, MINNEAPOLIS, MINN. Myocardial perfusion in the
hypertrophied heart (dogs).
•01 (ALY) JAKSCHIK, SISTER BARBARA A, WASHINGTON UNIVERSI
TY, 660 SOUTH EUCLID, ST LOUIS, MO, SRS-A-lts biosynthesis and ac-
tion.
•01 (CVB) BARRETT, JACK D, VETERANS ADMINISTRATION HOSP
16111 PLUMMER STREET, SEPULVEDA, CALIF. Iso-renins in the hyper-
tensive rat.
•01 (CVB) JULIUS, STEVO, UNIVERSITY OF MICHIGAN, R 6669
KRESGE MEO RES BLDG, ANN ARBOR, MICH. Blood volume distribution
in hypertension (human).
■01 (PC) ROHRBACH, MICHAEL S, MAYO FOUNDATION, 200 FIRST
STREET SOUTHWEST, ROCHESTER, MN. Pulmonary angiotensin convert-
ing enzyme (cattle)
-01 (CVB) WIEGMAN, DAVID I, UNIVERSITY OF MISSOURI, DALTON
RESEARCCH CENTER, COLUMBIA, MO. Hypertension, microvascular
control and exercise (rats)
•01 (SRC) FAROUHAR, JOHN W, STANFORD UNIVERSITY, DEPART
MENT OF MEDICINE, STANFORD, CALIF Stanford five city multifactor
risk reduction study
-01 (PC) SHIH, JASON C H, NORTH CAROLINA STATE UNIV, P 0 BOX
5307, scon HALL, RALEIGH, N C Biosynthesis of lipoic acid and
atherosclerosis (birds, chick embryos)
■01 (CVB) JEW, JEAN Y, UNIVERSITY OF IOWA, DEPARTMENT ANATO-
MY, IOWA CITY, IOWA. Studies of vasomotor control (rats)
■01 (CVB) GUTHRIE, GORDON P, JR, UNIVERSITY OF KENTUCKY
DEPARTMENT OF MEDICINE, LEXINGTON, KY. Adrenal steroids in
adolescent and adult hypertension.
•01 (PTHA) ROSKA, A KAY, MARQUETTE UNIVERSITY, 530 NORTH
15TH STREET, MILWAUKEE, WIS. Hypersensitivity pneumonitis in
guinea pigs.
576
R01HL-2178S
R01HL-21786
ROIHl-21791
ROIHl-21793
R01HL-21796
R01HL-21799
R01HL-21800.
R23HL-2180S-
R01HL-21812
R01HL-21817
ROIHl-21820
ROIHl-21829
R01HL-21831-
R23HI-21842-
R01HL-21843-
R01HL-21845
R01HL-21846
ROIHl-21849-
ROIHl-21850
R01HL-218S1-
R23HL-218S3
R23HL-2185S
R01HL-2I859
ROIHl-21860
ROIHL-21872
ROlHL-21874-
ROlHL-21877
ROIHL-21893.
R23HL-2I894
R23HI-2190I
■ ISHl-21906
ROIHL-21912
R23HL-2I9I4.
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■21922-01 (PHY) KASS, ROBERT S, UNIVERSITY OF ROCHESTER DEPT OF
PHYSIOLOGY, BOX 642, ROCHESTER, N Y. Transient currents induced
by strophanthidin in the heart.
■21943-01 (PTHA) MAZZONE, ROBERT W, UNIV OF CALIFORNIA, SAN
DIEGO, ROOM 5040 BASIC SCIENCES BLDG . W JOLU, CALIF. Capilla-
ry morphology in pulmonary edema (dogs).
21948-01 (PTHA) MORRIS, ALAN H, LATTER, DAY SAINTS HOSPITAL 325
8TH AVENUE, SALT LAKE CITY, UTAH. Capillary, tissue volume and
lymph flow in lung edema (sheep, cattle).
■21950-01 (PTHA) WALL, ROBERT T, HARBORVIEW MEDICAL CENTER 325
NINTH AVENUE, SEAHLE, WASH. Endothelial cell mechanisms in
vascular disease (human).
•21954-01 (AFY) ORENSTEIN, DAVID M, RAINVOW BAVIES & CHLDRNS
HOSP, 2101 ADELBERT ROAD, CLEVELAND, OHIO. Exercise conditioning
in patients with cystic fibrosis.
■21969-01 (SGYB) SWAN, HENRY, COLORADO STATE UNIVERSITY DEPT OF
CLINICAL SCIENCES, FORT COLLINS, COLO. Prevention of myocardial
hypoxia during by-pass (rats, mice, squirrels).
■21970-01 (CTY) ETLINGER, JOSEPH D, STATE UNIVERSITY OF NEW YORK
450 CURKSON AVENUE, BROOKLYN, N Y. Myofibrillar assembly and
breakdown in cardiac muscle (rats).
■21971-01 (EDO FRIEDMAN, GARY D, MED METHODS RES DEPARTMENT
3700 BROADWAY, OAKUND, CALIF. Atherosclerotic disease and risk
factors in twins (human).
21973-01 (CVA) ATKINS, FLOYD I, UNIVERSITY OF KANSAS, 3900 RAIN-
BOW BLVD, KANSAS CITY, KANS. Catecholamine metabolism and the
heart (human, guinea pigs).
■21975-01 (HEM) ROBERTS, HAROLD R, UNIVERSITY OF NORTH CAROLINA
BUILDING 229-H, CHAPEL HILL, N C. Studies on normal and abnormal
factor IX (human, dogs. cows).
•21985-01 (RAD) GRAHAM, THOMAS P, JR, VANDERBILT UNIVERSITY,
NASHVILLE, TENN. Videoroentgenography in congenital heart disease
■21988-01 (HEM) lOWENHAUPT, ROSALIN W, UNIVERSITY OF CONCIN
NATI, DEPARTMENT OF PHYSIOLOGY, CINCINNATI, OHIO. Biochemistry
of human platelet chemotaxis.
•21990-01 (AFY) LEWIS, STEVEN M, UNIV OF SOUTHERN CALIFORNIA.
BIOMEDICAL ENGINEERING, LOS ANGELES, CALIF. Accuracy of the ven-
tilatory response to exercise (dogs).
•21993-01 (CVB) SONNENBLICK, EDMUND H, ALBERT EINSTEIN COLL OF
MED, 1300 MORRIS PARK AVENUE, BRONX, N Y. Hypertensive hyper-
trophy-Effects of cardiac mechanics (rats)
■21994-01 (PTHA) AUSPRUNK, DIANNA H, CHILDREN'S HOSPITAL MED
CTR, 300 LONGWOOD AVENUE, BOSTON, MASS. Structure and develop-
ment of regenerating capillaries (rabbits, chick embryo).
21995-01 (PHRA) RUDOLPH, STEPHEN A, CASE WESTERN RESERVE UNIV
DEPT OF PHARMACOLOGY, CLEVEUND, OHIO. Protein phosphorylation
and adrenergic effects.
21996-01 (PHRA) lAGE, GARY I, UNIVERSITY OF WISCONSIN 425 N
CHARTER, MADISON, WIS. Alteration of digitalis and aldosterone
disposition (rats, rabbits, mice, dogs).
-21997-01 (PTHA) PENNINGTON, JAMES E, PETER BENT BRIGHAM
HOSPITAL. DEPARTMENT OF MEDICINE, BOSTON, MASS. Pulmonary im-
munopafhology in the compromised host (guinea pigs)
-22004-01 (CVB) KRONENBERG, MARVIN W, VANDERBILT UNIVERSITY
HOSPITAL, DIVISION OF CARDIOLOGY, NASHVILLE, TENN. Imaging and
EGG studies in acute and chronic IHD (human).
■22005-01 (SGYB) KORDENAT, R KARL, WRIGHT STATE UNIVERSITY 3525
SOUTHERN BOULEVARD, DAYTON, OHIO. Intermittent retropertusion of
ischemic myocardium (dogs).
■22008-01 (CVB) KIRBY, ALBERT C, CASE WESTERN RESERVE UNIV DE-
PARTMENT OF PHYSIOLOGY, CLEVEUND, OHIO. Left ventrivular calci-
um content and contractility (rats).
22011-01 (CVA) LESLIE, CRYSTAL A, BOSTON UNIVERSITY, 80 EAST CON-
CORD STREET, BOSTON, MASS. Adrenergic receptor cyclase system in
sensitized lung (rats, guinea pigs).
■22021-01 (DBR) RENNE, CHARLES M, NATIONAL ASTHMA CENTER 1999
JULIAN. DENVER. COLO. Asthma in families- Behavior analysis of
family interaction pattern.
•22022-01 (CVA) ROCHESTER, DUDLEY F, UNIVERSITY OF VIRGINIA, BOX
225, CHARLOnESVILLE, VA. Respiratory muscle dysfunction in respira-
tory failure (human).
■22026-01 (PHRA) MORRIS, HELEN G, NATIONAL JEWISH HOSP & RES CTR
3800 EAST COLFAX AVENUE, DENVER, COLO. Endogenous prostaglan-
dins in asthma.
•22029-02 (BM) JAKAB, GEORGE J, JOHNS HOPKINS UNIVERSITY 615
NORTH WOLFE STREET, BALTIMORE, MD. Bronchopulmonary resistance
to bacterial infection (mice).
-22032-01 (CVA) GOLDBERG, ALAN D, CLEVEUND METRO GENERAL
HOSP, 3395 SCRANTON ROAD, CLEVEUND, OHIO. Cardiovascular
events in hypertensives (human).
,-22035-01 (HEM) TENG, LIN-NAR I, UNIVERSITY OF WASHINGTON DEPT OF
UB MEDICINE, SB-10, SEATTLE, WASH. Molecular modification of
heparin by chemical means (sheep).
•22039-02 (PHRA) SCHWARTZ, ARNOLD, UNIVERSITY OF CINCINNATI
PHARMACOLOGY & THERAPEUTICS, CINCINNATI, OHIO Ion transport in
cardiac muscle (dogs, rodents, cattle).
22040-01 (CVB) BOUCEK, ROBERT J, JR, UNIVERSITY OF MIAMI DEPART-
MENT OF MEDICINE, MIAMI, FLA Regulation of lysylcross-linking in
vascular tissue (rats, turkeys)
-22050-01 (BBCB) CAPALDI, RODERICK A, UNIVERSITY OF OREGON IN
STITUTE/MOLECUUR BIOLOGY, EUGENE. OREG Organization of sue
cinic oxidase in heart
■01 (GMB) STREETEN, DAVID H, S U N Y UPSTATE MEDICAL CTR
750 EAST ADAMS STREET. SYRACUSE. N Y. Role of angiotensin II in
vasopressin release (human).
•22052-01 (BBCA) BITTMAN, ROBERT, QUEENS COLLEGE CUNY 65 30
KISSENA BLVD. FLUSHING, N Y Organization of free cholesterol in
serum lipoproteins (human, dogs).
■22053-02 (SRC) STEINBERG, DANIEL, UNIV OF CALIFORNIA, SAN DIEGO,
DEPT OF MEDICINE, M013D, U JOLU, CALIF. The disordered lipid
metabolism of diabetes mellitus (chickens, mammals, human).
.-22064-02 (SRC) INGEBRETSEN, WILLIAM R, JR, UNIVERSITY OF SOUTH
CAROLINA. DEPT PHYSIOLOGY & PHARMACOLOGY. COLUMBIA, S C.
Glycogen metabolism in anoxic diabetic myocardium (rats).
577
«01Ml.«065.01 (OBR) DAHIIM. NANO W, NAIIONAl JEWISH HOSP » RES
CTR, 3800 EASl COLfAX AVtNUf. OfNVFR, COLO Inliaclabihly. medi
cslion. and copinj styles m asthma (human)
m3Hl.aiO«8.01 (NSS) IIOBIN. EUOENI 0, SIANfORD UNIVERSITY. OEPARIMEN
OF MEDICINE C 3b?. SIANFORD. CALIF Contarence on 'The Internal
Enviionment' (Caliloinia) ,_.-..
IIOIMm069.02 (SGYA) MAXWEU, MORTON H, CEDARS SINAI MEDICAL
CENTER. 8/00 BFVERIY BOUlfVARD. LOS ANGELES. CALIF E.penmen
tal lenal arterial hypertension (dogs)
M3MH2075.01 (PC) WONG. PATRICK Y. UNIVERSITY OF TENNESSEE. 800
MADISON AVENUE. MEMPHIS. TENN Metabolism o( arachidonic acid in
blood vessels (chickens, mammals)
R01HI-M077.01 (CVA) ROTH, JEROME A, S U N Y AT BUFFALO. 127 FARBER
HALL. BUFFALO. N Y Vasoactive amine disposition in cultured en
dothelium (rabbits)
R01HH2079.01 (CVA) STUMPF. WAITER E. UNIV OF NORTH CAROLINA. ANATO
MY DEPARTMENT. CHAPEL HILL. N C Heart receptor sites lor digitalis
and steroid hormones (animals) .,r,^,^,.,r
ROlHl-HOSO-Ol (CVA) HOlllS. DONAIO P. JOHN HOPKINS SCH OF MEDICINE.
72b N WOLFE STREET. BALTIMORE. MD Phosphorus NMR studies on
cardiac tissue (rats, rabbits) ,„,,„., „rrro„r
R01HH2081.20 (BBCB) BENSUSAN. HOWARD B. CASE WESTERN RESERVE
ROIHI.22081 20JB ^.^^ ABINGTON ROAD. CLEVELAND. OHIO 44106 The
mechanism of collagen formation (human, cattle)
ROlHl-22087.02 (SSS) RYAN. JAMES W. UNIVERSITY OF MIAMI, P 0 BOX b2087b.
BISCAYNE ANNEX. MIAMI. FLA. Humoral mediators of pulmonary in
tiammation (guinea pigs) ,„.,.„r..„. mfm
ROIHI.22088.02 (SRC) GOIOSTEIN. GARY W. UNIVERSITY OF CALI ORNIA. NEU
ROLOGY DEPARTMENT, SAN FRANCISCO. CALIF Metabolic basis for
diabetic microangiopathy (cattle). „.„.,„„,. uncoiTAi
ROIHI.22098.01 (SGYB) SNIDERMAN, ALLAN D, ROYAL VICTORIA HOSPITAL,
* 687 PINE AVENUE WEST, QUEBEC H3A lAl. CANADA. Is postoperative
infarction due to repertusion injury? (human, dogs) ,,„,„,„.„„
R01Hl.2210.-02 (SRC) BAGBY, GREGORY JOHN. LOUISIANA STATE UNIVERSITY.
1542 TULANE AVENUE, NEW ORLEANS. LA. Hormone-substrate interac-
tion in diabetic myocyte (dogs. rats). .„.,^,m„,ti
ROtHl.22. 06-02 (SRC) TORNHEIM. PATRICIA A. UNIVERSITY OF CINCINNATI.
ANATOMY DEPARTMENT. CINCINNATI, OHIO. Diabetic cerebral vascular
RO,HL.22nO-02"(SGY;)"MdoRrwESLEY S. UNIVERSITY OF ARIZONA, SURGERY
DEPARTMENT, TUCSON. ARIZ. Healing complications in vascular gratt-
.OIHl 221 13.02"MrC)' WAGNER, f WIUIAM. JR. RANCHO LOS AMIGOS
R01Hl-22113.02^^(SRC) W^^^^ cOLONDRINAS STREET, DOWNEY, CALIF.
Micro/macrovasculature in healing of foot lesions (human)^ .,.,,^„o
ROIHl-221 15-02 (SRC) WEILS. .BERT C. CREIGHTON UNIVERSITY 2b00 CALIFOR-
NIA STREET. OMAHA, NEBR. Lipidmobilization and diabetic atheros-
tO.Hl-22118.02'TsRC)*''zWEtACH. BENJAMIN W. UNIV OF CALIFORNIA, SAN
DIEGO. AMES-BIOENGINEERING. MOOb. U lOLLA. CALIF. Microcircula-
tion in patients with diabetes mellitus „„„,.,., n,c
.O.Hl.22119.0. (HEM) DEUEl. THOMAS F. JEWISH HO PITAL 216
KINGSHIGHWAY. ST LOUIS. MO Biochemistry of platelet function in
thrombosis and cell grov»th (rabbits). „. .,..,.,rcc-rr oti
tO.Hl-22.2.-02 (SRC) SABESIN, SEYMOUR M. UNIVERSITY OF TENNESSEE. 9bl
COURT AVENUE. ROOM 335M. MEMPHIS. TENN. Dyslipoproteincmia in
diabetes and vascular disease (human)
R0.Hl.22. 23-02 (SRC) RANO. PETER W. MAINE MEDICAL CENTER. 22 BRAMHALL
STREET PORTLAND MAINE The role of the red cell in diabetic
atherosclerosis (human) „„...,r..T.oi.T
R0.Ml.22. 35-0. (SRC) KATZ, ARNOLD M. UNIVERSITY OF CONNECTICUT.
FARMINCION CONN Control ol calcium fluxes across cardiac mem-
branei (dogs rabbits guinea pigs)
.O.Hl.22. 36-02 (PHRA) JOHNSON. CARl I. UNIVERSITY OF CINCINNATI. 23
BflHtSDA AVfNUF CINCINNATI, OHIO Histamine and cardiac adenyl
■O.Ml.22. 37-02 'IcVA) BIOOM. SHERMAN. GEORGE WASHINGTON UNIVERSITY.
?300 I SIREFt N VK WASHINCION D C Structure function pathology
o( isolated heart cells (mice rals)
RO.Ml.22. 49.0. (PTHA) HART. MICHAEL N. UNIVERSITY OF IOWA. 0 PT OF
PAIHOIOCY IOWA CItY IOWA Morphologic eiamination ol brain
parenchymal vessels (cats)
R0.Ml.22. 52-02 (SGYA) ANDERSON. ROBERT W. UNIVERSIIY OF MINNESO A
BOX 118 MAYO MEMORIAL BLOG MINNEAPOLIS. MINN Ventricular
dyslunction and cardiac surgery (dogs)
RO.M1.22.S4.0. (AFY) STONE. HUBERT I. UNIVERSIIY OF OKLAHOMA. POST OF
FICE BOX 26901 OKLAHOMA CITY OKLA Cardiac adaptation to physi
R,3HL.22.S9.0."(NSS) mIssIrO. DONALD J. UNIVERSITY OF MIAMI. P 0 BOX
52087b, BISCAYNE ANNEX. MIAMI. FLA Conference on non ventilatory
functions of the lungs (New Hampshire)
PO.Hl.22.63.0. (HLBB) HOFFMAN. ALLAN S. UNIVERSITY OF WASHINGTON. CTR
F(DR BIOENGINEERING. FL 20 . SEAHLE. WASH. Surface thrombogene-
sis -Mechanisms and prevention.
P0.Hl.22. 63.0. 000. (HIBB) HORBETT, THOMAS A. Surface thrombogenesis
Mechanisms and prevention -Initial blood protein and platelet interac-
tions with biomaterials (baboons).
PO.Hl.22163.0. 0002 (HIBB) ISHIMARU. AKIRA. Surface thrombogenesis-
Mechanisms and prevention-Laser-scattering detection of microemboli
in blood flow (baboons).
PO.Hl.22163-0. 0003 (HIBB) HARKER. LAURENCE. Surface thrombogenesis-
Mechanisms and prevention -In vivo mechanisms of biomaterial
thrombogenesis and its prevention (baboons).
POlHl-22 163-01 9001 (HLBB) RABNER. BUDDY D. Surface thrombogenesis-
Mechanisms and prevention-Polymers for studing blood-material in-
teractions core. __ ..^„ „.^„ ,,„
R01H1.22 170-01 (PHRA) KIRPEKAR. S M. S U N Y - DOWNSTATE MED CTR, 450
CURKSON AVENUE. BROOKLYN. N Y. Factors influencing transmission
at adrenergic synpases
ROlHl-22172-01 (CVB) lEVINSKY. NORMAN G, UNIVERSITY HOSPITAL, 75 EAST
NEWTON STREET. BOSTON. MASS. Hypotension, renal ischemia and ef-
fect of mannitol (dogs. rats).
R01HL.221 74-01 (MBY) TZAGOIOFF, ALEXANDER A. COLUMBIA UNIVERSITY.
BIOLOGICAL SCIENCES DEPARTMENT. NEW YORK. N Y. Assembly of
membranes in heart and yeast mitochondria.
PROJECT NUAABER AND INVESTIGATOR ADDRESS
R01ML.22. 77.02 (CVA) ORiiN.ERO. STANLEY. UNIV OF SO"'H ALABAMA JfR'
Of PHARMACOIOGY. MOflllF AlA Mechanisms of control of pulmona
ry smooth muscle (dogs)
R0.Hl.22, 78-01 (RAO) JACKSON. ANDREW C. CHILORENS HOSPITAL. 300
lONGWOOD AVFNUF. BOS ION. MASS Lung airway property By
.itouslic impulse rclleclion „rr/uuii dc
ROIHL.22194.02 (BBCB) MALIK. MAZHAR N. INSI FOR BASIC RES/MNU Rf
TARD. lObO FOREST HILL ROAD. SIAIEN ISLAND. N Y Allosler.c func
tion of platelet contractile proleins (human) c..i,n«
ROIHI.22201.01 (TOX) FUHRMAN. FREDERICK A. HOPKINS MARINE STATION
STANFORD UNIVERSITY. PACIFIC GROVE. CALIF Pharmacology and
chemistry of nudibranch lonins (guinea pigs. rats, f";")^
RO.Hl-22208-02 (BBCB) FOSTER. JUDITH A. UNIVERSITY OF GEORGIA^ DEPART
MENT OF BIOCHEMISTRY. ATHENS. GA Elaslin structure, fibrogenesis
and disease (chichens, rabbits) „..„„,. r« rAur
ROlHl-222.2.01 (SRC) STROUD. FLORENCE M. 2134 GROVE. BERKELEY. CALIF
Alameda county high blood pressure control P'oe"'"„^_,,^„.,,^ ^..,
ROlHL-22215-01 (AFY) HOllOSZY. JOHN O. WASHINGTON UNIVERSITY. 4566
scon AVENUE. ST LOUIS. MO Eflects ol exercise training in ischemic
heart disease (human) ,. .o..,,
RO.Hl-222 16-02 (CVB) GREENBERG. STANLEY. UNIVERSITY OF SOUTH ALi^BAMA
COLLEGE OF MEDICINE, MOBILE, ALA Vascular mechanisms in renal
hypertension (dogs) _,„.„T..rMT nc
ROlHL-22219-01 (MCHA) PORTER. NED A. DUKE UNIVERSITY. DEPARTMENT OF
CHEMISTRY. DURHAM. N C. Prostacyclin and peroxides m blood and
R01HL-22223-0r(CVA7MEtBTN. JOIIOS. UNIVERSITY OF PENNSYLVANIA. 3800
SPRUCE STREET. PHILADELPHIA. PA The cardiopulmonary lunction
R01HL.22225.0iTvbTtERRAGNO. NORBERTO A. UNIVERSITY ()F TENNESSEE^
800 MADISON AVENUE. MEMPHIS. TENN. Hormonal regulation of blood
pressure and blood flow (human, animals)
RO.Hl-22226.01 (HED) PAPKA. RAYMOND E. UNIVERSITY OF KENTUCKY. 800
ROSE STREET. LEXINGTON. KY Autonomic nervous elements in tne
develoDine heart (rabbits).
ROlHl.22227-01 (HEM) STENT. GUNTHER S. UNIVERSITY OF CALIFORNIA. VIRUS
LABORATORY. BERKELEY. CALIF. A new source of hyaluronidasc and
anticoagulants (leeches),
ROlHl.22231-02 (PHY) SOIARO. R JOHN. UNIVERSITY OF CIN(;iNNATI. 23
BETHESDA AVENUE. CINCINNATI. OHIO Modulation of calcium control
of cardiac myofibrils (rats).
ROlHL-22233.01 (SGYB) APFEl, ROBERT E, YALE UNIVERSITY. ENGINEERING &
APPLIED SCI DEPT NEW HAVEN. CONN. Characterization of bio-materi-
R01HL-2223S-or(cir;rLS OERALD H. UNIVERSITY OF WASHINGTON,
DEPT OF ANESTHESIOLOGY RN-10, SEAHLE, WASH. Mechanism of car-
R0,HL.2223,-0,'rPHYTcAnUrrwaL.AM A. UNIVERSITY OF WASHINGTON^
SEATTLE. WASH. The molecular basis of electrical excitability (chick
R01HL-2224i-0r(PBC) WILSON. IRWIN B, UNIVERSITY OF COLORADO. CHEMIS-
TRY DEPARTMENT, BOULDER, COLO. The converting enzyme of lung
ROlHL-22244-OMrGYB) HAMMOND. GRAEME I. YALE UNIVERSITY. 333 CEDAR
STREET, NEW HAVEN, CONN. Cardiopulmonary bypass and the vascu-
lar endothelium (dogs).
R23HI-22245.02 (CVB) SAUM. WILLIAM R. GEORGETOWN UNIVERSITY. 37TH AND
0 STREETS. N W. WASHINGTON, D C. Functional characteristics of atri-
R01Hl.22252-0l''(BMT)°SMITH, KEVIN M, UNIVERSITY OF CALIFORNIA, CHEMISTRY
DEPARTMENT. DAVIS. CALIF. Synthesis of labeled hemes for protein
NMR studies.
R01H1.222S5-01 (EDO CRIQUI. MICHAEL H. UNIV OF CALIFORNIA, SAN DIEGO,
COMMUNITY MEDICINE DEPT, U JOLLA, CALIF. The etiology/prevalence
of peripheral arterial disease (human).
ROlHl-22257.0. (BM) MADERAZO. EUFRONIO G. HARTFORD HOSPITAL. DE-
PARTMENT OF MEDICINE, HARTFORD, CONN Leukokinesis enhancing
factor and lung infections (human, rats).
ROIMl-22258.01 (PHY) MAREN. THOMAS H. UNIVERSITY OF FLORIDA. BOX J-267
JHM HEALTH CENTER. GAINESVILLE. FU New aspects of pharmacology
related to carbonic anhydrase
ROIHl-22259-01 (TOX) ClARK. JAMES M. UNIVERSITY OF PENNSYLVANIA.
INST/ENVIRONMENTAL MEDICINE. PHILADELPHIA. PA Modification of
susceptibility to oxygen poisoning (rats)
ROIHl-22261-01 (CVB) TRIPPOOO, NICK C. ALTON OCHSNER MEDICAL FDN. 1516
JEFFERSON HIGHWAY. NEW ORLEANS. LA Compliance of fluid spaces
in advancing hypertension (rats)
ROlMl-22264-01 (PHY) CHACKO. SAMUEL K. UNIVERSITY OF PENNSYLVANIA.
3800 SPRUCE. PHILADELPHIA. PA 19104 Regulation ol contraction in
vascular smooth muscle (dogs)
ROlHl-22265-02 (BIO) MARTINEZ-CARRION. MARINO. MEDICAL COLLEGE OF
VIRGINIA. P 0 BOX 727. MCV STATION. RICHMOND. VA Isozymes of
heart glutamatc aspartate transaminase (swine, ducks)
ROlHl-22266.01 (SSS) RIFKIN. DANIEL B. NEW YORK MEDICAL SCHOOL. SbO
FIRST AVENUE. NEW YORK. N Y Production of proteases by lung cells
in culture (human, rodents, rabbits, sheep) ,„..„.,, p,,,n„
ROlHL.22269-01 (CVA) PARSONS. RODNEY L. UNIVERSITY OF VERMONT. GIVEN
MEDICAL BUILDING. BURLINGTON. VT. Excitation-contraction coupling
in enlarged hearts (rabbits). „..,.ro ,«c7 /ia
ROlHL-22270.01 (BBCA) SLAYTER. HENRY S. SIDNEY FARBER CANCER INST. 44
RINNEY STREET BOSTON. MASS. Platelet glycoprotein (human)
RO.HL.22273.01 (PHRA) FUNG. HO-LEUNG. S U N Y - AT BUFFALO. DEPT OF
PHARMACEUTICS, AMHERST, N Y. Oral and lung absorption ol
nitroglycerin (rats). „-.,-, ..,rcT
ROlHl.22274-01 SGYB) MOSKOW.TZ. MITCHELL S. SINAI HOSPITAL^ 6 67 WEST
OUTER DRIVE. DETROIT. MICH. Quantitating in series effects in car-
diac arrhythmias (dogs). .,.„ui.un
ROlHl.22281-01 (CVB) MERGNER, WOLFGANG J. UNIVERSITY OF MARYLAND^
22 SOUTH GREENE STREET. BALTIMORE. MD. Microprobe analysis and
metabolite levels of ischemic mycardium (dogs). <„„.„r„,c
ROlHL-22288-01 (PC) INAGAMI. TADASHI, VANDERBILT UNIVERSITY. BIOCHEMS^
TRY DEPARTMENT. NASHVILLE. TENN. Renin and precursors -Structure
and function (mice).
PROJECT NUMBER AND INVESTIGATOR ADDRESS
578
R01HL-22289
R01H1.22290.
ROIHl-22296
R01HL-22298
R01H1.2230I
ROIHl-22302.
R01HL-22306-
R23HL-22309
R0IHL.22313
R0)HL-223IS
ROIHL-22321.
R0IHL-2232S
R0IHU22326
ROIHL-22327
R01HL-22329
ROIHl-22333
R01HL-2233B
R0IHL-2234I
R23HL-2234S
R23HL-22345
R23H1.2234S
R23HL-22346
R0)HL-223S4
R01HL-223SS
R01H1.22361
R01HL.22367
ROIHl-22371.
ROIHl-22378
R01H1.22380
R23HI-22383
ROIHl.22387
ROIHl-22390-
ROIHL-22401
ROIHl-22402
ROIHL-22406
R0IHl.224n.
■°',„1^5**' "-OSKUTOFF, DAVID J, SCRIPPS CLINIC & RES FDN
ITJ^T 'T", ?'\'°'° ■ '' ""''■ "^'f Endoth L ce ;
mediated fibrinolysis (rabbits).
■01 (BIO) INGWAU, JOANNE S, PETER BENT BRIGHAM HOSPITAL
7 HUNTINGTON AVENUE. BOSTON. MASS. Cardiac energy meUbosm
and protein synthesis (mice). <=">um<im
■*",.l^^** ECKBERG, DWAIN L, VIRGINIA COMMONWEALTH UNIV
■12^00 EAST BROAD STREET, RICHMOND. VA. Autonomicrechanisms m
■° wnnn'^iv^M'^i^r^'o^Pr^*'"' "' ^HANNING LABORARTORY. 180 LONG-
WOOD AVENUE, BOSTON, MASS. Origins of hypertension (human)
\o.T^ MOORE, VERNON I, VETERANS ADMINISTRATION HOSP
m°„!T r'°"*l *'^""^' ^"O"' "^^ '--nogenetics of chro c
pulmonary inflammation (mice).
-01 (PTHA) REYNOLDS, HERBERT Y, YALE UNIVERSITY 333 CEDAR
TREET, NEW HAVEN, CONN. In,mune responses i^ the human ,„„'
(also rabbits, monkeys).
"° CH'A^kmnf.'^unfr l?''l" ,"' ""'^^SITY OF VIRGINIA. BOX 146.
CHARLOnESVILLE, VA. Renal catecholamines-- Pathophysiology of
hypertension (dogs)
■°'HOu''sTON*'TF°x'"f',^H°''' T'°. '' ^"*^ CHILDRENSS HOSPITAL.
H(^USTON, TEX Cardiovascular pharmacodynamics in immature dogs
innA frlJJ*"^"^' ^^"''Ol'- •». VIRGINIA MASON RESEARCH CTR
000 SENECA STREET, SEAHLE, WASH. Lung elastic recoil-Age and
disease (human).
■°Vc',fv°^,!lL"fr!"^^'^' '^^°^** "' "EPT OF CARDIOTHORACIC SUR-
GERY. 3400 SPRUCE STREET, PHILADELPHIA, PA Intraoperative car-
diac oxygen supply-demand (dogs, rabbits, rats)
■°V.f^*^''^' BOURLAND, JOE D, PURDUE UNIVERSITY BIOMEDICAL
ENGINEERING CENTER . WEST LAFAYEHE, IND. Cardiac output from
the pneumocardiogram (dogs).
■01 (BBCA) Gill, STANLEY J, DEPARTMENT OF CHIMSITRY UNIVER-
SITY OF COLORADO, BOULDER, COLO. Thermodynamics in respS
protein binding (human, trout).
■°'rj,?f^^* HISTAND, MICHAEl B, DEPARTMENT OF MECHANICAL
ENGR. COLORADO STATE UNIVERSITY. FORT COLLINS. COLO Noninva
sive measurement of cardiac output (dogs)
"°'c,t5°.r^*r°""^'^' ^°^** *• 3"* ™WNE BUILDING/D3, UNIVER-
SITY OF PENNSYLVANIA. PHIUDELPHIA. PA. Transport of arterial blood
gases through skin (swine).
'°\}!^lfl*i'^*^'"'°^"^- AOR'AN, SINAI HOSPITAL OF DETROIT.
6767 WEST OUTER DRIVE. DETROIT. MICH. Active prosthetic myocardi^
urn -Effects on LV function (dogs).
°nifX,'?;l'^.'^***''°' GlO«'A », UNIVERSITY OF MIAMI, POST OF-
FICE BOX 520875, MIAMI, FU. Cellular basis of small airNvays tunc-
tion (rats).
"°'.M'n^^nL'"!f"*'"'*°^' '""" °- BROWN UNIVERSITY, BARUS
AND HOLLEY BUILDING, PROVIDENCE, R I. Platelet adhesion and ag-
gregation in a flow chamber (human).
-01 (PTHA) KOIETSKY, SIMON, INSTITUTE PATHOLOGY 2085
ADELBERT ROAD, CLEVEUND. OHIO. Pathogenesis of atherosclerosis
in rats,
•02 (SSS) BROWNEll, KEllY D, UNIVERSITY OF PENNSYLVANIA 205
PIERSOL BUILDING, PHILADELPHIA, PA. Behavioral cardiovascular 'com-
pliance strategies.
02 0001 (SSS) BROWNEll, KEllY D. Behavioral cardiovascular
compliance strategies -Long term modification of dietary patterns
(human).
-02 0002 (SSS) BROWNEll, KEllY D. Behavioral cardiovascular
compliance strategies-Compliance with antihypertensive medication
regimens (human).
-01 (SGYB) ADOONIZIO, V PAUl, UNIVERSIfy OF PENNSYLVANIA
HARRISION OEPT SURGICAL RES, PHILADELPHIA, PA. Hematological in:
lury and pulmonary dysfunction (human, mammals)
-01 (CVA) KRUGER, FRED A, OHIO STATE UNIVERSITY, PHYSIOLOGI-
CAL CHEMISTRY DEPT. COLUMBUS. OHIO. Alpha-adrenergic effects on
heart metabolism (rats).
■01 (HEM) WEINSTEIN, MARK J, BOSTON VA HOSPITAL 150 SOUTH
HUNTINGTON AVENUE, BOSTON. MASS. Purification, structure and
function of factor VIII (human).
-01 (AFY) BALDWIN, KENNETH M, UNIVERSITY OF CALIFORNIA DE-
PARTMENT OF PHYSIOLOGY. IRVINE. CALIF. Regulation of cardiac
adaptation to exercise (rats).
-01 (CTY) HARDIN, JAMES, BAYLOR COLLEGE OF MEDICINE 1200
MOURSUND AVENUE, HOUSTON, TEX Estrogen receptors in very low
density lipoproteins (chicken livers).
■01 (RAO) BIGIER, RODNEY E, SLOAN-KETTERING INSTIUTE 410
EAST 68TH STREET, NEW YORK. N Y. Vascular changes in lung ex-
posed to radiation
•01 (EDO lEITCH, CYNTHIA J, UNIVERSITY OF WASHINGTON CMNTY
HLTH CARE SYSTEMS OEPT, SEAHLE, WASH. Psyco-somatic predictors
of CHD in adolescence (human).
•-01 (SRC) GOOIEY, AlEGRO J, HERMAN KEIFER HLTH COMPLEX
1151 TAYLOR. DETROIT, MICH Detroit hypertension control program
■01 (BIO) HANCE, AllAN J, STANFORD UNIVERSITY DEPT OF
RESPIRATORY MEDICINE, STANFORD, CALIF, Biosynthesis-Response to
oxygen depletion (human, primates, rats)
■01 (BMT) RIORDAN, JAMES F, BIOPHYSICS RESEARCH LABORATO-
RY, 721 HUNTINGTON AVE, BOSTON, MASS, Metalloenzymes and dis-
ease
■01 (CVB) KOTCHEN, THEODORE A, UNIVERSITY OF KENTUCKY
DEPARTMENT OF MEDICINE. LEXINGTON, KY. Effect of chloride on renin
(rats, dogs).
-01 (PBC) PEMRICK, SUZANNE M, S U N Y -DOWNSTATE MED CTR
DEPT OF BIOCHEMISTRY, BROOKLYN, N Y. Regulation of tension and
active state in the heart.
■01 (SSS) WEST, SEYMOUR S, UNIVERSITY OF ALABAMA, UNIVERSITY
STATION. BIRMINGHAM. AU. Heparin-biophysical, chemical and biolog-
ical aspects (mice, human),
■01 (AFY) D'AOUST, BRIAN G, VIRGINIA MASON RESEARCH CENTER
1000 SENECA STREET. SEAHLE. WASH. Isobaric vascular bubbles and
decompression sickness (goats, models).
■01 (CVB) MORRIS, MARIANA, BOWMAN GRAY SCHOOL OF
MEDICINE. 300 S HAWTHORNE RD. WINSTON-SALEM, N C. Neuroen-
docrine involvement in hypertension (rats).
ROIHl.22413-01 (SGYB) D-AQUST, BRIAN G, VIRGINIA MASON RESEARCH
„, K kkI '"""SENECA STREET, SEAniE. WASH. Enhanced detection
of bubbles in Doppler flow signals (human)
■22415-01 (CVA) BROOKS, STUART M, UNIVERSITY OF CINCINNATI 231
BETHESDA AVENUE, CINCINNATI. OHIO. Mechanisms responsible for
disease severity in asthma (human)
22417-01 (SGYB) KOIVO, ANTTI J, SCHOOL OF ELECTRICAL ENGR PUR-
DUE UNIVERSITY. WEST UFAYETTE. IND. Microprocessors in medical
applications (dogs).
-22418-01 (CVA) HARPER, RONALD M, CENTER FOR THE HEALTH
SCIENCES. UNIVERSITY OF CALIFORNIA. LOS ANGELES. CALIF Neural
control of cardiorespiratory function (cats)
■22426-01 (PHY) GILES, WAYNE R, UNIVERSITY OF WASHINGTON
CENTER/BIOENGINEERING RF-52. SEAHLE. WASH. Initiation of the
heartbeat -A voltage-clamp study (bullfrogs, rabbits)
'^^*"'°\.cf.V^^l ''"'^°' "-""^ ^- ^^'^^NE STATE UNIVERSITY. DEPART-
METNT OF CHEMISTRY. DETROIT. MICH. Molecular studies of human
erythrocyte membranes.
22435-02 (CVA) GIAUSER, FREDERICK I, MEDICAL COLLEGE OF VIRGINIA
BOX 93 1200 E BROAD STREET. RICHMOND. VA. Pulmonary alveolar^
capillary permeability characteristic (dogs)
22437-01 (PTHB) KREUTZER, DONALD I, UNIVERSITY OF CONNECTICUT
DEPARTMENT OF PATHOLOGY. FARMINGTON. CONN Leukotactic media^
tors in lung inflammatory reactions (rats, rabbits, human)
22438-01 (CVB) REINECK, HENRY J, UNIVERSITY OF TEXAS. 7703 FLOYD
CURL DRIVE. SAN ANTONIO. TEX. The etiology of genetic hypertension
(rats).
22444-01 (PTHA) REID, lYNNE M, CHILDREN'S HOSPITAL MED CENTER
300 LONGWOOD AVENUE. BOSTON. MASS. Bronchial mucus production
in organ culture (human).
■22445-01 (SGYB) KAVE, MICHAEl P. MAYO FOUNDATION. 200 FIRST
STREET SOUTHWEST. MINNEPOLIS. MINN. Platelet inhibitors-Effect on
coronary bypass grafts (dogs).
•22446-01 (CVA) SANDBERG, LAWRENCE B, UNIVERSITY OF UTAH DE-
PARTMENT OF PATHOLOGY, SALT UKE CITY, UTAH. Chemical and func-
tional studies of low copper in lung (pigs)
-22448-01 (SGYA) NOWYGROD, ROMAN, COLUMBIA-PRESBYTERIAN MED
CTR DEPARTMENT OF SURGERY. NEW YORK. N Y. Modulation of heart
graft antigenicity by perfusion (rats)
-22455-01 (SGYB) ECKSTEIN, EUGENE C, UNIVERSITY OF MIAMI. P 0 BOX
48294 CORAL GABLES. FU. Platelet concentration in the marginal
layer (dogs, human).
■"''""°MrirrfMc'^„°c!!,"„'„-'*^^ "' '^'"■""^'* COLLEGE, DEPARTMENT OF
MEDICINE, NEW YORK, N Y. Lipoproteins in bioregulation of the im-
mune response (mice, human).
-22461-01 (BBCB) lEHRER, SHERWIN S, BOSTON BIOMEDICAL RES INST
20 STANIFORD STREET, BOSTON, MASS. Cardiac tropomyosin and
tropomyosin-action interactions (rabbit)
-22463-02 (CVA) Gil, JOAN, HOSP OF UNIV OF PENNSYLVANIA 874
MALONEY BLDG HUP/Gl, PHIUDELPHIA, PA. Pinocytotic vesicles and
pulmonary edema (rats).
■22470-01 (CVA) CARIDE, VICENTE J, YALE UNIVERSITY, 333 CEDAR
STREET, NEW HAVEN, CONN. Liposome myocardial uptake in infarct
and ischemia (dogs, rats. mice).
■22471-01 (HEM) OWEN, WHVTE G, UNIVERSITY OF IOWA. DEPARTMENT
OF PATHOLOGY, IOWA CITY. IOWA. Biochemistry of prothrombin quick
(human).
■22472-01 (EDO FISHER, EDWIN B, JR, WASHINGTON UNIVERSITY DEPART-
MENT OF PSYCHOLOGY. ST LOUIS. MO. Smoking risk-factor reductr-
Maintenance strategies (human).
22474-01 (MET) FOGEIMAN, ALAN M, UNIVERSITY OF CALIFORNIA
10833 LE CONTE AVENUE, LOS ANGELES. CALIF. Cholesterol 1™:
ism and atherosclerosis (rats, human, rabbits)
22482-01 (CVB) HUMPHREYS, MICHAEl H, SAN FRANCISCO GENERAL
HOSPITAL, ROOM 350 BUILDING 100, SAN FRANCISCO. CALIF Circula-
tory hemodynamics and sodium excretion (dogs)
22484-01 (CVA) MARTIN, PAUL J, MT SINAI HOSPITAL 1800 E 105
STREET. CLEVELAND. OHIO. Neural control of cardiac conduction and
excitation (dogs),
-22486-01 (BIO) SLAKEY, LINDA I, UNIVERSITY OF MASSACHUSEnS
BIOCHEMISTRY DEPARTMENT. AMHERST. MASS. Enzyme regula.onn
cultured arterial cells (swine).
■22490-01 (PHRA) HARDEN, T KENDAll, UNIVERSITY OF NORTH
CAROLINA, PHARMACOLOGY DEPARTMENT, CHAPEL HILL N C Neu-
rotransmitter receptors of cultured heart cells
•22500-01 (HED) ZACHMAN, RICHARD D, UNIVERSITY OF WISCONSIN
2 2 SOUTH PARK STREET, MADISON. WIS. Conversion of choline to
phosphatidylcholine in lung (rabbits pigs)
-22502-01 (HEM) RITTENHOUSE-SIMMONS, SUSAN, VETERANS ADMINIS-
TRATION HOSP. 150 SOUTH HUNTINGTON AVENUE. BOSTON MASS
Role of phosphoinositides in human platelet secretion
■22505-01 (HEM) MCDONAGH, RICHARD P, JR, UNIVERSITY OF NORTH
CAROLINA. OEPT OF PATHOLOGY. 228-H. CHAPEL HILL N C 27514
,,.«. Molecular pathology of fibrinogen and factor XIII (human, animals)
■22506-01 (CVB) FROHLICH, EDWARD D, ALTON OCHSNER MEDICAL FDN
1516 EFFERSON HIGHWAY. NEW ORLEANS. U. Hemodynamics of the
clinical hypertensions.
■22512-01 (RAD) HARTLEY, CRAIG J, THE METHODIST HOSPITAL 6516
BERTNER. HOUSTON, TEX. Ultrasonic instrumentation for cardiovascu-
lar studies.
22514-01 (EDO GLASS, DAVID C, C U N Y AT NEW YORK, 33 WEST 42
STREET. NEW YORK. N Y. Behavior patterns, stress, and
catecholamines.
-22517-01 (SGYB) MC CARTNEY, MICHAEl I, WASHINGTON UNIVERSITY
BOX 11270ELECTRICAL ENGR DEPT , ST LOUIS, MO. Engineering
development of an ultrasonic ventilometer (human)
•22520-01 (PTHA) STAHIMAN, MILDRED T, VANDERBILT UNIVERSITY DE
PARTMENT OF PEDIATRICS, NASHVILLE. TENN. Pulmonary vascular
response to group B Streptococci (human, mammals)
•22522-01 (PHRA) RZESZOTARSKI, WACIAW J, GEORGE WASHINGTON
UNIVERSITY. 2300 EYE STREET N W. WASHINGTON, D C Cardioselec-
tivity of beta-ad renoceptor antagonists.
•22525-01 (NSS) ROCHESTER, DUDLEY F, PULMONARY DIVISION - BOX
225, UNIVERSITY OF VIRGINIA, CHARLOHESVILLE. VA, International
symposium on the diaphragm (Virginia).
ROIHl
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5/9
PROJECT NUMBER AND INVESTIGATOR ADDRESS
R01Hl-I3Sa7-OI (CVB) BAILfY, JOHN M, GEORGE WASHINGION UNIVERSITY.
2300 EYE STREET N W. WASHINGTON. D C Piostacyclin thromboiianes
in tha caidiovasculat system (human, (abbits)
R01Hl-3aS2l-03 (IDC) TAOfR. IRA B, PETER BENT BRIGHAM HOSPITAL. 7?l
HUNTINGTON AVINlJf, BOSTON MASS Eaily (isk predictors loi chionic
pulmonary disease (humiin)
R0IHI-22S30-01 (SSS) POWERS, JAMES C, SCHOOL OF CHEMISTRY. GEORGIA
INST OF TECHNOLOGY ATLANTA. GA Active site studies on blood
proteases (human)
R01HI-22S33-0I (MET) SCHROEPFER. GEORGE J. JR. RICE UNIVERSITY. DE
PARTMENT OF BIOCHEMISTRY, HOUSTON. TEX Inhibitors ol cholesterol
biosynthesis (rats. mice, yeast)
R0IHL-23S38-0I (BIO) IYENGAR, MEIKOTE R, UNIVERSITY OF PENNSYLVANIA.
3800 SPRUCE STREET. PHILADELPHIA, PA. Myosin as a multienzyme
complex (dogs, rabbrts)
ROIHl-22546-02 (CVA) ECKBERC, DWAIN L, MEDICAL COLLEGE OF VIRGINIA. DE
PARTMENT OF MEDICINE. RICHMOND. VA Baioreceplor rellex
mechanisms in man
R0IHI-22S47-01 (EOC) SURWIT, RICHARD S, DUKE UNIVERSITY. BOX 3416. DUR
HAM. N C Behavioral treatment ol Raynaud's disease (human)
R01HI-22S49.02 (CVA) TAYLOR, AUBREY E, COLLEGE OF MEDICINE. UNIVERSITY
OF SOUTH ALABAMA. MOBILE. ALA Transport across alveolar capillary
membrane (dogs)
R01HI-22SS0-02 (CTY) LEMANSKI, LARRY F. UNIVERSITY OF WISCONSIN. 1255
LINDEN DRIVE. MADISON. WIS Genetic cardiomyopathies in salaman
ders and hamsters
R0THI-22SS2-02 (PTHA) EGAN, EDMUND A, CHILDRENS HOSPITAL, 219 BRYANT
STREET. BUFFALO. N Y Abnormal alveolar permeabrlity and lung dis
ease (sheep)
R0IHI-225S5-0I (SSS) PiNCKARD, ROBERT N, UNIVERSITY OF TEXAS. 7703
FLOYD CURL DRIVE. SAN ANTONIO. TEX Structure and lunction ol
platelet activating lactor (rabbits, human)
R01HL-22S60-02 (CBY) SATIR, PETER, ALBERT EINSTEIN COLLEGE OF MED. 1300
MORRIS PARK. BRONX. N Y Structure and motion ot cilia
(Tetiahymena. mussels)
R0IHL-22S6I-01 (PHY) FARA, JOHN W, JOHNS HOPKINS HOSPITAL. 601 NORTH
BROADWAY. BALTIMORE. MD Hormonal control ol mesenteric circula-
tion (cats)
R01HL-22S62-02 (PHY) JOYNER, RONALD W, UNIVERSITY OF IOWA, DEPT OF
PHYSIOLOGY & BIOPHYSIC, IOWA CITY, IOWA Mechanism o( cardiac
action potential propagation (tunicates).
R01HL-22S63-02 (CVB) DUNN, MICHAEL J, CASE WESTERN RESERVE UNIV.
MEDICINE DEPARTMENT. CLEVELAND, OHIO. Prostaglandins, the kidney
and hypertension (rats)
ROIHl-22566-01 (MCHA) ROGERS, MICHAEL E, VIRGINIA COMMONWEALTH UNIV.
MCB STATION BOX 666. RICHMOND. VA Mesoionic punnones as
phosphodiesterase inhibitors
R01HL-22S67-01 (MET) SAMUEL, PAUL, ROCKEFELLER UNIVERSITY. 1230 YORK
AVENUE. NEW YORK. N Y Validation of a cholesterol absorption
method in man.
ROIHl-22568-01 (PHRA) MC CALL, DAVID, UNIVERSITY OF CONNECTICUT,
HEALTH CENTER, FRAMINGTON. CONN pH effect in heart cells-In-
fluence of cardiac drugs (tissue culture, rats)
R01HL-32S69-02 (PHY) TAYLOR, AUBREY E, UNIVERSITY OF SOUTH ALABAMA, DE
PARTMENT OF PHYSIOLOGY, MOBILE. ALA. Intestinal secretion-Capilla-
IV and tissue forces (dogs, cats).
ROIHL-22570-OI (NSS) REYNOLDS, JACQUELINE A, DUKE UNIVERSITY.
BIOCHEMISTRY DEPARTMENT, DURHAM, N C. Interactions of sterols in
biological systems (human).
R01HL-22573-0T (SGYB) ZERVAS, NICHOLAS T, MASSACHUSETTS GENERAL
HOSPITAL, FRUIT STREET. BOSTON. MASS. Treatment of post surgical
vasoconstriction (dogs, monkeys, human, rats).
R23HI-22S7S-0I (PHRA) TAUBERT, KATHRYN A, UNIVERSITY OF CALIFORNIA.
PROGRAM IN BIOMEDICAL SCIENCES. RIVERSIDE. CALIF. Factors modi-
fying cardiac digoxin effects and content (dogs. cats).
R0IHL-22S8I-02 (SRC) ECKBERG, DWAIN I, VIRGINIA COMMONWEALTH UNIV.
1200 EAST BROAD STREET. RICHMOND. VA. Neurocirculatory control in
diabetes mellitus (human).
R01HL-22582-0T (IMS) HALONEN, MARILYN J, UNIVERSITY OF ARIZONA. DE-
PARTMENT OF MICROBIOLOGY. TUCSON. ARIZ. Pulmonary and circula-
tory alterations induced by IGE
ROIHl-22583-02 (PTHA) MASON, REGINALD G, JR, UNIVERSITY OF SOUTH
FLORIDA. MDC BOX 11. TAMPA. FU Ultrastructural study of endotheli-
um in thrombosis (human)
ROIHL-22585-01 (SGYB) CHUANG, HANSON Y, UNIVERSITY OF SOUTH
FLORIDA. OEPT OF PATHOLOGY. TAMPA. FLA Plasma proterns adsorbed
to artificial organs (human, rabbits)
ROIHL-22S94-01 (CVB) ZUCKER, IRVING H, UNIVERSITY OF NEBRASKA. 42ND &
DEWEY AVENUE. OMAHA. NEBR. Reflex control of the circulation in
heart failure (dogs)
P01HL-22602-01 (HLBB) COTRAN, RAMZI S, PETER BENT BRIGHAM HOSPITAL.
721 HUNTINGTON AVENUE. BOSTON. MASS Pathophysiology of the en
dothelium
POIHl-22602-01 0001 (HLBB) GIMBRONE, MICHAEL A, JR. Pathophysiology of
the endothelium Platelet endothelial interactions in vitro (human, cat
tie)
POIHl-22602-01 0002 (HLBB) VENKATACHALAM, MANJERI A. Pathophysiolo
gy of the endothelium Molecular charge and endothelial permeability
(rats, mice)
POIHl-22602-01 0003 (HLBB) COTRAN, RAMZI S. Pathophysiology of the en-
dothelium-Mechanisms of endothelial proliferation (human, animals).
POIHL-22602-01 0004 (HLBB) STEMERMAN, MICHAEL. Pathophysiology of the
endothelium -Endothelium, platelets smooth muscle and atherosclero-
sis (rabbits)
POIHl-22602-01 9001 (HLBB) VENKATACHALAM, MANJERI A. Pathophysiolo-
gy of the endothelium-Morphology core
POIHl-22602-01 9002 (HLBB) GIMBRONE, MICHAEL A, JR. Pathophysiology of
the endothelium -Core-Culture ot blood vessel -Derived cells.
ROIHL-22603-01 (CVB) HALL, CHARLES E, UNIVERSITY OF TEXAS. PHYSIOLOGY
AND BIOPHYSICS DEPT, GALVESTON, TEX. Trace metals, vascular ac-
tivity and hypertension (rats).
ROIHl-22604-01 (SGYB) JACOBS, JOHN E, NORTHWESTERN UNIVERSITY. 2145
SHERIDAN ROAD, EVANSTON, ILL. Non-invasrve system for arlerrosclero-
sis studies (human).
ROIHL-72607-OI (MET) HAZZARD, WILLIAM R. HAHIIORVIIW MIUICAI lENTIK
326 9IH AVENUE. SEAIIll. WASH Role ol apolipopiotein E in
lipoprotein metabolism (human)
R01HL-22612-01 (MCHA) SCHWARTZ. JIFFRIY, PRINCETON UNIVERSITY.
CHEMISIRY DIPAKIMFNI. PRINCITON. N 1 Stabili;ed piotlacyclins to
treat vascular disease
R01HL-22617-OI (CVB) BLAINE. EDWARD H. TEMPLE UNIVERSITY. 3420 N
BROAD STRFFT. PHIIADFIPMIA. PA Angiotensin, hypertension and the
CNS (sheep)
ROIHl-22618-OI (MET) KASHYAP. MOTI I. CINCINNATI GENERAL HOSPITAL. 734
GOODMAN STREET. CINCINNATI. OHIO Role ol apolipoproteins in hyper
triglyceridemia (human)
P01HL-226I9-01 (HLBB) SCHWARTZ, ARNOLD, UNIVERSITY OF CINCINNATI. 231
BFTIIfSDA AVENUE. CINCINNATI. OHIO Cellular mechanisms of hearl
lailuie
P01HL-226I9-01 0001 (HLBB) LANE. LOIS K. Cellular mechanisms ol heart
failure Cell membrane rsolation and reconstitution (dogs, lambs)
P01HL-226 19-01 0002 (HLBB) COLLINS. JOHN. Cellular mechanisms ol heart
lailure Structure of sodium, potassium adenosine triphosphatase
(lambs, dogs)
POIHl-22619-01 0003 (HLBB) SCHWARTZ. ARNOLD. Cellular mechanisms ol
heart failure Digitalis induced inotropy in myocardial ischemia heart
failure (animals)
POIHL-22619-01 0004 (HLBB) WAllICK, EARL. Cellular mechanisms of heart
failure Mechanism of action of Na. K ATPase (sheep, cattle)
POIHl-22619-01 0005 (HLBB) POTTER. JAMES D. Cellular mechanisms of heart
failuie Molecular mechanism ol regulation of cardiac muscle contrac
tion (cattle)
POIHL-22619-01 0006 (HLBB) SOLARO. R JOHN. Cellular mechanisms of heart
failure Phosphorylation of contractrle proteins in cardiac muscle con-
traction (dogs, rabb
POIHl-22619-OI 0007 (HLBB) MARTIN. ANNE F. Cellular mechanisms of heart
failure- Regulation of contractile protein levels in heart muscle (rats)
POIHL-22619-01 0008 (HLBB) DISAIVO. JOSEPH. Cellular mechanisms of heart
failure- Molecular mechanisms and differential contractile responsive
ness in VSM (dogs)
POIHl-22619-01 0009 (HLBB) SOLARO. R JOHN. Cellular mechanisms of heart
failure -Sarcoplasmic reticulum in cardiac, skeletal and smooth
muscle (rabbits, dogs)
POIHL-22619-01 0010 (HLBB) MATUB, M ABDUL. Cellular mechanisms of heart
failure-Mitochondria in heart and smooth muscle (rabbits, rats,
dogs)
POIHL-22619-01 0011 (HLBB) JACKSON, RICHARD. Cellular mechanrsms of
heart failure -Reaction of lipoproterns and apolipoproteins »»ith
lipoprotein lipase (cattle)
POIHl-22619-01 0012 (HLBB) KASHYAP, MOTI L. Cellular mechanisms of heart
failure -Apolipoproteins in hypertriglyceridemia (human)
POIHL-22619-01 9001 (HLBB) FRANKLIN, DEAN. Cellular mechanisms of heart
failure -Experimental pathological models core.
POIHL-22619-01 9002 (HLBB) WALLICK, EARL. Cellular mechanisms of heart
failure -Medicinal chemistiy and clinical intervention
POIHL-22619-01 9003 (HLBB) MANDEL, FREDERIC. Cellular mechanisms of
heart failure-Computer facility core.
R23HL-22621-01 (HEM) HEBBEL. ROBERT P. UNIVERSITY OF MINNESOTA. BOX 480
MAYO MEMORIAL BUILDING. MINNEAPOLIS. MINN. Blood cell-mediated
pulmonary (human).
R01HL-22622-0I (CVA) BLOCK. A JAY. UNIVERSITY OF FLORIDA. BOX )-225 JHM
HEALTH CENTER. GAINESVILLE. FLA Sleep apnea and desaturation-
mechanisms and incidence (human)
R01HL-22623-01 (CVB) BAGDADE. JOHN D. PROVIDENCE MEDICAL CENTER, 500
17TH AVENUE. SEATTLE. WASH Polyamines cellular mediators of
atherogenesis (human).
ROIHL-22627-01 (SGYB) MASON. REGINALD G. JR. UNIVERSITY OF SOUTH
FLORIDA. 12901 N 30TH STREET, BOX 11, TAMPA, FLA An inhibitor of
platelet adhesion to artificial organs (human).
P01HL-22633-01 (HLBB) MARSH. JULIAN B, MED COLL OF PENNSYLVANIA, 3300
HENRY AVENUE, PHILADELPHIA, PA. Cellular and molecular biology of
lipoprotein metabolism.
P01HL-22633-01 0001 (HLBB) MARSH, JULIAN B. Cellular and molecular biolo-
gy of lipoprotein metabolism-Secretion of lipoproteins by the perfused
liver (rats, rabbits).
P01HL-22633-01 0002 (HLBB) ROTHBLAT, GEORGE. Cellular and molecular
biology of lipoprotein metabolism -Sterol metabolism in tissue culture
cells.
P01HL-22633-01 0003 (HLBB) SCHICK, PAUL K. Cellular and molecular biology
of lipoprotein metabolism -Sterol metabolism in platelets and megaka-
ryocytes (human, rabbits, guinea pigs).
P01HL-22633-01 0004 (HLBB) PHILLIPS, MICHAEL C. Cellular and molecular
biology of lipoprotein metabolism- Lipid lipid and lipid-protein interac-
tions in serum lipoproteins (human, rats)
POIHl-22633-01 9001 (HLBB) ROTHBLAT, GEORGE. Cellular and molecular
biology of lipoprotein metabolism Tissue cultuie core
POIHL-22633-01 9002 (HLBB) MARSH, JULIAN B. Cellular and molecular biolo
gy ol lipoprotein metabolism Lipopiolein laboratory core
ROIHl-22636-01 (SGYB) GRAUSZ, JOHN P, MILWAUKEE COUNTY MED COMPLEX.
8700 WEST WISCONSIN AVENUE. MILWAUKEE. WIS Newborn lung tunc
tion during mechanical ventilation (human)
ROIHl-22641-01 (CVB) LEVITZKY, MICHAEL G, LOUISIANA STATE UNIVERSITY.
1542 TULANE AVENUE. NEW ORLEANS. LA Ventilation, perfusion, and
systemic arterial rellexes (dogs)
ROIHL-22650-01 (HEM) MILLER, MARILYN E, BROOKHAVEN NATIONAL U60RAT0
RY. MEDICAL DEPARTMENT. UPTON. N Y. Regulatory mechanisms ol
erythropoietin production (human, rats. mice).
R01HL-22651-01 (PBC) MARTIN, ANNE F, UNIVERSITY OF CINCINNATI. 231
BETHESOA AVENUE. CINCINNATI. OH Control of protein metabolism in
heart muscle.
R01HL-226S4-0I (BBCB) JOSEPHS, ROBERT, UNIVERSITY OF CHICAGO. 950 EAST
58TH STREET. CHICAGO. ILL. Molecular structure of sickle cell fibers
(human).
R01HL-22661-01 (SGYB) MORTENSEN, J D, UNIVERSITY OF UTAH. 520 WAKARA
WAY. SALT LAKE CITY, UTAH Chronic total cardiopulhonary mechanical
substitution (sheep).
R01HL-22664-01 (CVA) HOLLENBERG, MILTON, VETERANS ADMINISTRATION
HOSP, 4150 CLEMENT STREET, SAN FRANCISCO, CALIF. Regulation of
myocardial cell grovith (rats/ guinea pigs).
PROJECT NUMBER AND INVESTIGATOR ADDRESS
ROIHl-22667
R23HI-22669.
R01HL-2267I
R01HL-22676-
ROIHl-22682
ROIHL
ROIHt
'22685
22699
R01HL-22715
R0IHL-227I8
ROIHl.22723
R23Ht-22728
ROIHl-22729.
R01HL-22732-
R01HL-22738
ROIHL-22739
ROlHl-22740
R01HL.22741.
R23HL-2274S-
R23HI-22747
R01HL-22748-
R01HI-227S0-
ROIHl-22759
ROlHL-22767-
R01HL-2277I
R23HL-22775
ROIHl-22778
ROIHl-22780
ROIHl-22783
ROlHl-22784.
R23HI-22787.
R23HL-22799.
R0)Hl.2280l
ROIHl.22802
ROIHl-22809
R01HL-228I2
■01 (CVB) KOUSHANPOUR, ESMAIL, NORTHWESTERN UNIVERSITY
303 EAST CHICAGO AVENUE. CHICAGO. ILL. Mechanisms of barorecep-
tor adaptation in hypertension (dogs).
■01 (CVB) lONGHURST, JOHN C, UNIVERSITY OF TEXAS 5323
HARRY HINES. DALUS, TEX. Cardiovascular effects from visceral af-
ferents (dogs)
■01 (HEM) KAY, MARQUERITE M B, VA WADSWORTH HOSPITAL
CENTER. WILSHIRE & SAWTELLE BLVDS. LOS ANGELES, CALIF. Removal
of senescent and stored human red cells.
-01 (PTHA) RICHERSON, HAL B, UNIVERSITY HOSPITALS. ALLERGY-
IMMUNOLOGY DIVISION. IOWA CITY, IOWA. Pathogenesis in experimen-
tal interstitial pneumonitis (rabbits).
■01 (BBCB) TAIL, ALAN R, COLUMBIA UNIVERSITY, 630 WEST 168TH
STREET. NEW YORK. N Y. Structure and function of high density
lipoprotein (human, rat).
01 (PHRA) WIGGINS, JAY R, 12901 NORTH 30TH STREET, TAMPA,
FLA. Drugs and excitation-contraction coupling in heart (animals)
01 (SGYB) TACKER, WILLIS A, JR, PURDUE UNIVERSITY A A
POTTER ENGINEERNING CENTER. WEST LAFAYEHE, IND. Defibrillation
electrode studies (dogs, swine).
-01 (CVA) KENDRICK, JOHN E, UNIVERSITY OF WISCONSIN 470
NORTH CHARTER STREET, MADISON, WIS. Neural integration of the
cardiovasculai reflexes (dogs)).
-01 (PHRA) ABRAMSON, FRED P, GEORGE WASHINGTON UNIVERSI-
TY, 2300 EYE STREET, N W, WASHINGTON, 0 C. Cardiovascular drug
interactions-Metabolism models (dogs).
-01 (CVA) PETTY, THOMAS L, UNIVERSITY OF COLORADO, 4200 EAST
NINTH AVENUE, DENVER, COLO The morphologic basis of airflow ob-
struction (human).
■01 (CVB) BLAIR, MARTHA L, UNIVERSITY OF ROCHESTER 601 ELM-
WOOD AVENUE. ROCHESTER. N Y. Neural control of renin secretion
(dogs),
■01 (PBC) BIENKOWSKI, ROBERT S, ALBERT EINSTEIN COLLEGE OF
MED. 1300 MORRIS PARK AVENUE. BRONX, N Y. Intracellular degrada-
tion of newly synthesized collagen (human, chick, rabbit)
■01 (CVA) FOREMAN, ROBERT D, UNIVERSITY OF OKLAHOMA POST
OFFICE BOX 26901. OKLAHOMA CITY, OKLA. Central organization of
cardiac afferent nerves (cats, monkeys).
•01 (CVB) MAYROVITZ, HARVEY N, MIAMI HEART INSTITUTE 4701
NORTH MERIDIAN AVENUE, MIAMI BEACH, FLA. Role of bioelectric
potentials in platelet adherence (bats, rats, hamsters)
-01 (PTHA) STARY, HERBERT C, LOUISIANA STATE UNIVERSITY DE-
PARTMENT OF PATHOLOGY. NEW ORLEANS. U Evolution and progres-
sion of pediatric atherosclerosis.
-01 (EDO WILLIAMS, REDFORD 8, JR, DUKE UNIVERSITY, BOX
3416. DURHAM, N C. Behavior and cardiovascular disease -Basic
mechanisms (human).
■01 (SGYA) BERNSTEIN, EUGENE F, UNIV OF CALIFORNIA SAN
DIEGO, DEPARTMENT OF SURGERY, SAN DIEGO. CALIF. Arteriovenous
connections in extremity revascularization (dogs).
•01 (CVB) BORDERS, STEPHEN E, UNIVERSITY OF CALIFORNIA DE-
PARTMENT OF PATHOLOGY M-012 . LA JOLLA, CALIF Vascular
mechanics and structure in hypertension (miniature swine).
01 (NEUA) DORMER, KENNETH J, UNIVERSITY OF OKLAHOMA
POST OFFICE BOX 26901, OKUHOMA CITY. OKLA. Cardiodynamics and
hypertension under cerebellar control (dogs)
•01 (MET) WITZTUM, JOSEPH I, WASHINGTON UNIVERSITY 4566
scon AVENUE. ST LOUIS. MO. Effect of bile sequestration on VLDL
metabolism (human).
■01 (CVB) JOHNSON, ROBERT A, MASSACHUSEHS GENERAL
HOSPITAL, CARDIAC UNIT, MEDICAL SERVICES, BOSTON, MASS. Digoxin
in heart failure with sinus rhythm (human).
■01 (SGYB) TACKER, WILLIS A, JR, PURDUE UNIVERSITY, BIOMEDI-
CAL ENGINEERING CENTER , WEST UFAYETTE, IND. Regional myocardi-
al blood flow during hypothermia (dogs).
01 (PHY) RAMON, FIDEL, DUKE UNIVERSITY. DEPARTMENT OF
PHYSIOLOGY, DURHAM, N C. Model system for cardiac action poten-
tials (squid, axons).
-01 (BBCB) DOMBROSE, FREDERICK A, UNIVERSITY OF NORTH
CAROLINA. DEPARTMENT OF PATHOLOGY. CHAPEL HILL, N C. Throm-
bogenic phospholipid surfaces (cattle).
■01 (PHRA) GALPER, JONAS 8, PETER BENT BRIGHAM HOSPITAL
721 HUNTINGTON AVENUE, BOSTON, MASS. Muscarinic receptors in the
developing heart (chick embryo).
•01 (MCHA) WA18A, DAVID M, UNIVERSITY OF COLORADO, DE-
PARTMENT OF CHEMISTRY, BOULDER, COLO. Total synthesis of natural
cardiotonic ionophores
01 (HEM) TAYLOR, JOHN F, HEALTH SCIENCES CENTER, POST OF-
FICE BOX 35260. LOUISVILLE. KY. Factors modifying the reaction pro-
perties of HgS (human).
-01 (SGYB) IMPARATO, ANTHONY M, NEW YORK UNIV MED
SCHOOL. 550 FIRST AVENUE. NEW YORK. N Y. Hemodynamic induction
of intimal fibromuscular lesion.
-01 (SGYB) IMPARATO, ANTHONY M, NEW YORK UNIVERSITY 550
FIRST AVENUE. NEW YORK. N Y Ductus arteriosus closure -An arterial
lesion model (rabbits)
-01 (SGYB) SCHILLER, NELSON 8, UNIVERSITY OF CALIFORNIA
ADULT NONINVASIVC LABORATORY. SAN FRANCISCO. CALIF Cardiac
volume by biplane echocardiography (human)
-01 (HEM) DAVIS, ALVIN E, III, CENTER FOR BLOOD RESEARCH
800 HUNIINCION AVfNUF. BOSTON. MASS Interaction of the comple
meni and coagulalioii syslem^ (monkeys)
•01 (SGYB) WILLIAMS, THOMAS E, JR, OHIO STATE UNIV
HOSPIIAIS 410 W TENTH AVENUE. COLUMBUS. OHIO Analysis of coro
nary artery behavior (dogs)
-01 (EDC) BARANOWSKI, TOM, WEST VIRGINIA UNIVERSITY 3110
MACCORKLE AVENUE. S E. CHARLESTON. W VA A rural mining com-
munity hypertension control proiecl (human)
-01 (EDC) DEM8ROSKI, THEODORE M, ECKERD COLLEGE P 0 BOX
12560. ST PETERSBURG. FLA Coronarv-prone behavior and car-
diovascular reactivity (human).
•01 (MET) WILCOX, HENRY G, UNIVERSITY OF MISSOURI. DEPART-
MENT OF PHARMACOLOGY. COLUMBIA, MO Regulation of hepatic
production of HDL (rats).
580
ROlHL-22813-01 (CVB) PITTS, BARRY J, BAYLOR COLLEGE OF MEDICINE 1200
MOURSUND AVENUE. HOUSTON. TEX. Palmitylcarnitine inhibition of ion
pumps in ischemia (dogs).
ROlHL-228 15-01 (SGYB) WIENER, LESLIE, lEFFERSON MEDICAL COLLEGE DIVI-
SION OF CARDIOLOGY, PHILADELPHIA, PA. Regional myocardial func-
tion after revascularization (dogs).
R23HL-228 18-01 (PBC) CHENG, PI-WAN, CASE WESTERN RESERV UNIVERSITY
2101 ADELBERT ROAD. CLEVEUND, OHIO. Biosynthesis of human
respiratory mucous glycoprotein (also dog).
ROIHl-22821-01 (BMT) HAWKRIOGE, FRED M, VIRGINIA COMMONWEALTH UNIV
DEPARTMENT OF CHEMISTRY, RICHMOND. VA. A routine screening
analysis for myoglobinemia.
R23HI-22823-01 (BM) WARR, GLENN A. lOHNS HOPKINS UNIVERSITY 615 NORTH
WOLFE STREET. BALTIMORE, MD. Phagocytic and immune defense
mechanisms of the lung (mice).
ROlHL-22828-01 (CVB) DOBSON, JAMES G, JR, UNIVERSITY OF MAS-
SACHUSETTS. 55 UKE AVENUE NORTH, WORCESTER. MASS. Adenosine
and catecholamine interaction in the heart (rats)
ROlHL-22836-01 (CVB) STEELE, THOMAS H, UNIVERSITY OF WISCONSIN 1300
UNIVERSITY AVENUE. MADISON, WISC. The spontaneously hypertensive
kidney (rats),
ROlHL-22838-01 (EDC) STEVENS, CLADD E, NEW YORK BLOOD CENTER INC 310
EAST 67TH STREET. NEW YORK. N Y. Post-transfusion hepatitis in
newborn children.
R23HL-22839.01 (MBY) OSTRO, MARC J, UNIVERSITY OF ILLINOIS. 835 SOUTH
WOLCOTT. CHICAGO. ILL Cellular translation of liposomally-delivered
mRNA (human, mammals).
ROlHl-22843-01 (CVA) SHAFFER, THOMAS H, TEMPLE UNIVERSITY 3420 NORTH
BROAD STREET. PHILADELPHIA. PA. Pulmonary physiology in liquid
ventilation (lambs).
ROlHl-22844-OI (SGYB) LEVITSKY, SIDNEY, UNIVERSITY OF ILLINOIS POST OF-
FICE BOX 6998. CHICAGO, ILL. Phrenic nerve pacing-lioninvasive
diaphragm analysis (human, dogs).
R01HL-22845.01 (PHY) LITTEN, RAYE Z, III, UNIVERSITY OF VERMONT COLLEGE
OF MEDICINE. BURLINGTON, VT. Response of cardiac myosin to hyper-
trophic stress (rabbits).
ROlHl.22847-01 (NTN) INSULl, WIlllAM, JR, METHODIST HOSPITAL 6516
BERTNER BLVD. HOUSTON. TEX, Test for adherence to diets rich in
linoleic acid.
R01HL-22852-01 (SGYB) BARNES, ROBERT W, MEDICAL COLLEGE OF VIRGINIA
BOS 221 - MCV STATION. RICHMOND. VA Diagnostic techniques irl
venous thromboembolism (human).
ROlHL-22854-OI (SGYB) BUNAG, RUBEN D, UNIVERSITY OF KANSAS 39TH ST &
RAINBOW BLVD. KANSAS CITY. KANS. Non-invasive blood pressure
measurement (rats).
ROlHl.22859-01 (HED) PENNEY, DAVID G, WAYNE STATE UNIVERSITY DEPART-
MENT OF PHYSIOLOGY, DETROIT, MICH. Effect of carbon monoxide on
the developing heart (rats).
ROlHl-22862-01 (CVA) RUSKIN, JEREMY N, MASSACHUSEHS GENERAL
HOSPITAL, FRUIT STREET, BOSTON. MASS. CNS-mediated effects of an-
tiarrhythmic drugs (dogs).
ROlHl-22868.01 (NLS) lOKHANDWAlA, MUSTAFA F, UNIVERSITY OF HOUSTON
4800 CALHOUN BLVD. HOUSTON. TEX. Presynaptic regulatory
mechanisms in hypertension (rats, dogs).
ROlHl-22873-Ol (END) HOIL, JAMES E, UNIVERSITY OF GEORGIA DEPARTMENT
OF PHARMACOLOGY. ATHENS, GA. Adrenoceptor interconversion and
hormone homeostasis.
ROlHl-22875-01 (TOX) MARKLAND, FRANCIS S, JR, UNIV OF SOUTHERN
CALIFORNIA. 1720 ZONAL AVENUE. LOS ANGELES. CALIF. Crotalase-
Chemistry, physiology, clinical potential (rats, rabbits)
R23HI-22882.0I (PHRA) BRATER, DONALD C, UNIVERSITY OF TEXAS 5323
HARRY HINES BOULEVARD, DALUS, TEX. Modulation by disease of ef-
fect of furosemide in man
ROIHI.22883.01 (PTHA) ROSEN8AUM, ROBERT M, ALBERT EINSTEIN COLLEGE
OF MED, 1300 MORRIS PARK AVENUE, BRONX, N Y. Lung epithelial
cell interactions in vitro.
ROlHL.22888-01 (SGYB) ANDERSON, JAMES M, CASE WESTERN RESERVE UNIV
OLIN BUILDING. ROOM 702, CLEVELAND. OHIO. Prosthetic valve en-
docarditis-Etiology and therapy (dogs).
R01H1.22893-01 (SGYB) RUTHERFORD, ROBERT B, UNIVERSITY OF COLORADO
4200 EAST NINTH AVE, BOX C-312, DENVER. COLO. Evaluating arterial
disease by velocity-wave analysis (dogs, human)
R01HL-22894-01 (SGYB) SPOTNITZ, HENRY M, COLUMBIA UNIVERSITY DEPART-
MENT OF SURGERY. NEW YORK, N Y. Two dimensional ultrasound and
cardiac surgery (human, dogs).
R23HI-22895-01 (PTHA) LOKE, JACOB S, YALE UNIVERSITY. 155 WHITNEY
AVENUE. NEW HAVEN, CONN 06511. Smoke inhalation-Biochemical
and cellular responses (rabbits, bacteria).
ROlHl-22896-01 (BIO) RYAN, JAMES W, UNIVERSITY OF MIAML SCHOOL OF
MEDICINE. MIAMI. FLA. Immediate metabolic fates of kinins and an-
giotensins (rat. rabbit, guinea pig).
R01HL.22910-01 (CVB) YOUNES, MAGDY K, JOHN SEALY HOSPITAL UNIVERSITY
OF TEXAS MED BRANCH. GALVESTON. TEX. Control of breathing pat-
tern in health and disease (human, animals)
ROIHI.22911.01 (CVB) GEE, MARIYS H, JEFFERSON MEDICAL COLLEGE 1020
LOCUST STREET. PHIALDELPHIA. PA Mechanism of clearance of lung
edema fluid (dogs)
ROIHl-22917.01 (CVB) NEILIS, STEPHEN H, MILTON S HERSHEY MEDICAL CTR
DEPARTMENT OF MEDICINE. HERSHEY. PA Microvascular pressures in
the intact beating heart (rabbits)
R23Hl.22920.01 (CVA) lORING, STEPHEN H, HARVARD UNIVERSITY 665
HUNTINGTON AVENUE. BOSTON. MASS Dynamic airway behavior
(dogs),
ROlHl.22924-01 (CVA) BOUCHER, RICHARD C, UNIVERSITY OF NORTH
CAROLINA. 724 CLINICAL SCIS BLOG 229 H. CHAPEL HILL. N C. The
airway mucosal barrier (guinea pigs),
ROIHL.22928.01 (CVB) MAGNO, MICHAEL, UNIVERSITY OF PENNSYLVANIA 3600
SPRUCE STREET. PHIUDELPHIA. PA. Systematic study of bronchial cir-
culation (sheep).
R23HL.22932.01 (CVB) METCALF, JOHN F, MEDICAL UNIV OF SOUTH CAROLINA
171 ASHLEY AVENUE, CHARLESTON, S C. Effect of carbon dioxide on
local gas exchange (dogs)
R23Hl.22933.01 (CVB) ROSELLI, ROBERT J, VANDERBILT UNIVERSITY. ROOM B-
3211, NASHVILLE. TENN. Transvascular fluid and protein exchange in
the lung (sheep).
SSI
PROJECT NUMBER AND INVESTIGATOR ADDRESS
RiaHl.23934-01 (EDO OREEN, LAWRENCE W. JOHNS HOPKINS UNIVERSITY. 61b
N0R1H WOirt STREET. BALTIMORE. MO Behsvonal approaches to
adolescent hypedcnsion
ROIHL-23939-01 (CVB) SPRAOO, JOCEIYN. SEEIEY G MUDD BUILDING RM 625.
250 LONGWOOD AVENUE. BOSTON. MASS Human k{nm and libnnolytic
systems and icnal disease (human)
R01Hl-a2946-0l (CVB) MORETTI. RICHARD I, CHILDREN'S HOSPITAL. SIST &
GROVE STREETS. OAKLAND. CALIE Pfoslaglandms. platelet aggfega
tion and vasoaclivily (human, lats, obbits)
R33HL-22947-01 (SSS) MC ALISTER, ALFRED I. HARVARD SCHOOL OE PUBLIC
HLIH. 677 HUNIINGTON AVENUE, BOSTON. MASS tipetimenlal
systems to imptouc youth behavior (smoking prevention)
R01HI-229SI-01 (HEM) STEINER, MANFRED, MEMORIAL HOSPITAL. PROSPECT
STREET. PAWTUCKET. R I Studies on the ailed o( vitamin E on
platelets (human, rats)
R01HI-229S2-01 (CVB) GOULD, KENNETH I. SEAHIE VA HOSPITAL. CADIOLOGY
SERVICE. SEATTLE. WASH Validation of quantitative coronary arteriog
raphy (dogs)
R0IHL-229SS-01 (HEM) SIIVERBERG, SIDONIE A. S U N Y AT STONY BROOK.
DIVISION OE HEMATOLOGY. STONY BROOK. N Y. inetics of prothrombin
activation
R23HL-229S9-01 (CVB) KIDO, PARRIS M, UNIVERSITY OE CALIFORNIA. DEPART
MENT OF ANATOMY. SAN FRANCISCO. CALIF Heart development in in-
herited cardiomyopathy (hamsters)
R01HL-22963-0I (SSS) HUTCHINS, GROVER M. )OHNS HOPKINS HOSPITAL. DE-
PARTMENT OF PATHOLOGY. BALTIMORE. MD Symbohc logic analysis of
congenital heart disease (human)
ROIHL-22967-OI (MET) BROWN, W VIRGIL, MT SINAI SCHOOL OF MEDICINE. 5TH
AVE & lOOTH STREET. NEW YORK. N Y Structure and function of
heparin leleasable lipases (sv»inc. human).
R23HI-22972-0I (CVB) LOMBARD, JULIAN H, MEDICAL COLLEGE OF WISCONSIN.
DEPARTMENT OF PHYSIOLOGY. MILWAUKEE. WISC. Microcirculatory
(unction in hypotension (rats, hamsters)
R23HI-2297S-01 (CVB) MOHRMAN, DAVID E, UNIVERSITY OF MINNESOTA.
PHYSIOLOGY DEPARTMENT. OULUTH. MINN. Dynamics of autoregulation
of muscle blood flow (dogs).
ROIHL-22976-OI (CVB) MITTMAN, CHARLES, CITY OF HOPE MEDICAL CENTER.
1500 EAST DUARTE ROAD. DUARTE. CALIF, Nonuniform ventilation and
diffusing capacity (human),
R01HL-22977-01 (CVB) COHN, JAY N, UNIVERSITY OF MINNESOTA. BOX 488. MIN-
NEAPOLIS. MINN. Role of vasoconstrictor mechanisms in heart failure
(human, dogs).
R01HL-229S0-01 (HEM) NEMERSON, YALE R, MOUNT SINAI MEDICAL SCHOOL.
lOOTH STREET & FIFTH AVENUE. NEW YORK. N Y. Kinetic and
mechanistic studies of blood coagulation (human, cattle)
R01HL-22981-17 (MBC) WEBER. MORTON M, ST LOUIS UNIVERSITY. 1402 SOUTH
GRAND BOULEVARD. ST LOUIS. MO, Membrane-associated functions in
microorganisms (bacteria, protozoa).
ROIHL-22982-01 (EDC) MOSS, ARTHUR J, UNIVERSITY OF ROCHESTER. 601 ELM-
WOOD AVENUE. ROCHESTER. N Y, Multicenter postcoronary risk
stratification program (human),
ROIHl-22983-01 (PC) JENG, INGMING, WASHINGTON UNIVERSITY. BOX 8046.
4566 SCOTT AVENUE. ST LOUIS. MO, Studies on the catabolism of
plasma lipoproteins (rats),
R23HL-229B4-01 (BIO) SINGH, DIWAN, UNIVERSITY OF IOWA. DEPT OF ANATOMY.
IOWA CITY. IOWA, Cyclic AMP dependent protein kinases in hyperten-
sion (rat),
R0IHL-2298S-01 (BBCA) SAIDE, JUDITH D, BOSTON UNIVERSITY, 80 EAST CON-
CORD STREET. BOSTON. MASS. Properties and assembly of Z-disk
proteins (human, other species).
R01HL-22990-01 (CVB) DOUGLAS, JANICE G, CASE WESTERN RESERVE UNIV.
2065 ADELBERT ROAD. CLEVELAND. OHIO. Angiotensin II receptors -
Mechanisms of regulation (rats).
R01HL-22996-01 (TOX) KRESS, LAWRENCE F, ROSEWELL PARK MEMORIAL INST.
666 ELM STREET. BUFFALO. N Y, Venom proteases-Action on plasma
protease inhibitors (human),
R01HL-23003-01 (BBCB) BROCKMAN, HOWARD L, JR, UNIVERSITY OF MIN-
NESOTA. 801 16TH AVENUE. N E. AUSTIN. MINN, Bulk-surface distribu-
tion of cholesteryl esters,
R01HL-230 10-01 (CBY) GARTNER, THEODORE K, MEMPHIS STATE UNIVERSITY.
BIOLOGY DEPARTMENT. MEMPHIS. TENN, Control and mechanism of
platelet aggregation (human),
R01HL-23013-01 (CBY) FERNANDEZ, SALVADOR M, UNIVERSITY OF CONNEC-
TICUT. PHYSIOLOGY DEPARTMENT. FARMINGTON. CONN. Smooth
muscle development in vitro (chick embryo).
ROIHl-23015-01 (CVA) WEIL, MAX H, USC SCHOOL OF MEDICINE. 2025 ZONAL
AVENUE. LOS ANGELES. CALIF, Mechanisms of hypo-oncotic pulmonarv
edema (human, dogs).
R01HL-2302S-01 (CVB) DOWEll, RUSSELL T, UNIVERSITY OF OKUHOMA, POST
OFFICE BOX 26901. OKLAHOMA CITY, OKLA, Adaptive heart growth in
neonates and adults (rats),
ROIHl-23071-01 (SRC) MOORE, E NEIL, UNIVERSITY OF PENNSYLVANIA. 3800
SPRUCE STREET. PHILADELPHIA. PA, Electrophysiology of lethal arr-
hythmias (dog. human).
R13HL-23C72-01 (NSS) GERGELY, JOHN, BOSTON BIOMEDICAL RES INST, 20
STANIFORD STREET. BOSTON. MASS, Gordon Research Conference -Car-
diac and skeletal muscle (New Hampshire),
R01HL-23078.01 (SRC) RUBERMAN, WILLIAM, HLTH INSURANCE PUN. 625
MADISON AVENUE. NEW YORK. N Y Psychosocial stress and sudden
coronary death (human)
ROIHl-23108-01 (HEM) VICTORIA, EDWARD J, JR, UNIV OF CALIFORNIA. SAN
DIEGO. T003. LA JOLLA. CALIF Membrane biochemistry of RH an
tigens (human)
ROIHl-231 14-01 (SGYA) PRANCAN, ARTHUR V, ST LUKES MEDICAL CENTER.
DEPT OF PHARMACOLOGY. CHICAGO. ILL 60612, Control of platelet ag-
gregation in shock (dogs, rabbits)
ROIHl-231 15-01 (NSS) EDELMAN, ISIDORE S, COLUMBIA UNIVERSITY. DEPT OF
BIOCHEMISTRY. NEW YORK. N Y, Regulation of active sodium trans
port (frogs, rats)
ROIHL-23120-01 (BMT) BALDWIN, JACK E, UNIVERSITY OF OXFORD. SOUTH
PARKS ROAD. OXFORD 0X1 3QY. ENGLAND Chelating agents as blood
substitutes.
ROIHl-23128-01 (PHY) DONALDSON, SUE K, RUSH-PRESBY-ST LUKES MED CTR.
1753 W CONGRESS PARKWAY. CHICAGO. ILL. Cardiac contractility-
Ischemia and hypoxia (rabbits, rats).
ROIHl-231 3801 (SRC) JENNINGS, ROBERT B. DUKE UNIVERSITY. BOX 3/17.
PAIHOIOCY. DURHAM. N t Myocardial iichemn (dogs. rats, chick
embryo)
ROIHL-23140-01 (SRC) BRAUNWAID, EUGENE, PETER BENT BRIGHAM
HOSPIIAL. DEPI OF MEDICINE. BOSION. MASS Deltrminanlj of irr
eversible ischemic iniury in lieart (dog. rat)
ROIHl-23 142-01 (SRC) WEGIICKI, WILLIAM B, VIRGINIA COMMONWEALTH UNIV.
1200 EASI BROAD STREET. RICHMOND. VA Mechanisms of membrane
injury in myocardial isctiemia (dog)
ROIHl-231 53-01 (SRC) SORDAHL, LOUIS A, UNIVERSITY OF TEXAS. DIVISION OF
BIOCHEMISTRY. GALVESTON. TEX Mechanisms of altered CA?0 trans
port in ischemic heart (dog. rabbit)
ROIHl-231 59-01 (NTN) CLARKE, STEVEN D, 122 VIVIAN HALL. 2121 FYFFE ROAD.
COLUMBUS. OHIO Regulation of lipogenesis by polyunsaturated fats
(rats, chicks)
R01HL-23161-01 (SRC) ENTMAN, MARK L, BAYLOR COLLEGE OF MEDICINE. OEPT
OF MEDICINE. HOUSTON. TEX Biology of myocardial ischemia
ROIHl-23161-01 0001 (SRC) WOOD, JEANIE M. Biology of myocardial
ischemia Mitochondrial lipid metabolism and cardiac ischemia (rat.
dog)
ROIHL-23161-01 0002 (SRC) PITTS, BARRY J R. Biology of myocardial ischemia -
Paimitylcarnitine inhibition of ion pumps in myocardial ischemia (dog.
sheep)
ROIHl-231 61-01 0003 (SRC) ENTMAN, MARK L. Biology of myocardial ischemia-
-Phosphorylase coupling to myocardial sarcoplasmic reticulum (dog)
ROIHl-23161-01 0004 (SRC) GOLDSTEIN, MARGARET A. Biology of myocardial
ischemia -Structure of myofibrils and membranes in early ischemia
(dogs, rabbit, rodents)
ROIHL-23161-01 0005 (SRC) ROSSEN, ROGER D. Biology of myocardial
ischemia -Localization of complement in myocardial infarction (dog)
ROIHL-231 66-0 1 (SRC) BRIERLEY, GERALD P, OHIO STATE UNIVERSITY.
PHYSIOLOGICAL CHEMISTRY DEPT. COLUMBUS. OHIO Pathology o(
mitochondria in ischemic myocardium (rats, cattle),
R01HL-23171-01 (SRC) KIRK, EDWARD S, ALBERT EINSTEIN COLL OF MED. 1300
MORRIS PARK AVENUE. BRONX. N Y Coronary collateral circulation in
myocardial ischemia (dog. pig. rat. human).
ROIHL-231 83-01 (PHY) HALL, JAMES E, UNIVERSITY OF CALIFORNIA. PHYSIOLOGY
DEPARTMENT. IRVINE. CALIF Voltage dependent conductance in mem-
branes
ROIHL-23 194-02 (TEC) SIERVOGEL. ROGER M, EELS RESEARCH INSTITUTE.
WRIGHT STATE UNIV SCH OF MED. YELLOW SPRINGS. OHIO, Genetics
of hypertension and associated variables (human),
R01HL-23200-01 (HEM) OHNISHI, TSUYOSHI, HAHNEMANN MED COLL &
HOSPITAL. 230 NORTH BROAD STREET. PHILADELPHIA. PA, Isolation of
CA binding proteins from erythrocytes (human),
ROIHL-23201-01 (HLBA) DUSTAN, HARRIET P, UNIVERSITY OF AUBAMA. UNIVER-
SITY STATION. BIRMINGHAM. ALA, Mechanisms of hypertension
(human, rats),
R01HL-23205-01 (SRC) SIEGMAN, MARION J, JEFFERSON MEDICAL COLLEGE.
1025 WALNUT STREET. PHILADELPHIA. PA, Contraction of pulmonary
vascular smooth muscle (cat),
R01HL-23206-01 (AFY) STONE, HUBERT L, UNIVERSITY OF OKUHOMA. POST OF
FICE BOX 26901. OKUHOMA CITY. OKU, Repetitive exercise and car-
diac enlargement (dogs).
ROIHl-23209-01 (SRC) BUCKNER, CARL K, UNIVERSITY OF WISCONSIN. 425 N
CHARTER STREET. MADISON. WIS, Autonomic receptors of the pulmo-
nary vasculature (mammals),
R01HL-23210-01 (SRC) BERGOFSKY, EDWARD H, S U N Y AT STONY BROOK.
DEPT OF MED/PULMONARY DIS DIV . STONY BROOK. N Y, Biology of
normal and hypertrophied pulmonary vessels (cat. human),
ROIHl-232 11-01 (SRC) WEIR, EDWARD K, VETERANS ADMINISTRATION HOSP.
54TH ST AND 48TH AVE SO. MINNEAPOLIS. MINN. Active normoxic pul-
monary vasodilatation (rat. dog, sheep),
R01H 1-232 24-01 (SRC) SOBIN, SIDNEY S, CARDIOVASCUUR RESEARCH LAB. BOX
1800 - 1200 NORTH STATE ST. LOS ANGELES. CALIF, Hypoxia and pul-
monary vascular smooth muscle (rat. cat),
R01HL-23232-01 (SRC) REID, LYNNE M, CHILDREN'S HOSPITAL. 300 LONGWOOD
AVENUE. BOSTON. MASS. Effect of hypoxia on PVSM and its precursor
cells,
R01HL-23233-01 (SRC) JOHNSON, PETER, OHIO UNIVERSITY. CHEMISTRY DEPART-
MENT. ATHENS. OHIO, Pulmonary artery intermediate filament struc-
ture (cattle),
R01HL-23239-01 (SRC) PIEPER, HEINZ P, OHIO STATE UNIVERSITY. 333 WEST
lOTH AVENUE. COLUMBUS. OHIO. Functional characteristics of pulmo-
nary vascular smooth muscle (dogs).
R01HL-23240-01 (SRC) PAUL, RICHARD J, UNIVERSITY OF CINCINNATI. 231
BETHESDA AVENUE. CINCINNATI. OHIO. Pulmonary vascular muscle
metabolism and contractility (rats, cattle).
R01HL-2324S-01 (SRC) GILliS, CHARLES N, YALE UNIVERSITY, 333 CEDAR
STREET, HEW HAVEN. CONN, Adrenergic receptors in pulmonary vascu-
lar muscle (human, animal).
R01HL-23249-01 (SRC) SEIDEl, JOHN C, BOSTON BIOMEDICAL RES INST. 20
STANIFORD STREET. BOSTON. MASS, Actin-myosin interaction in pulmo-
nary smooth muscle (cattle),
R01HL-23267-0I (BBCB) LITT, MITCHELL, UNIVERSITY OF PENNSYLVANIA. 383C
TOWNE 8UILDING/D3. PHIUDELPHIA. PA, Rheology and kinetics of
hemoglobin S gelation (human),
P60HL-23282-0I (SRC) SATCHER, DAVID, C R DREW POSTGRAD MED SCH. 1621
EAST 120TH STREET. LOS ANGELES. CALIF Comprehensive
hospital/community sickle cell center
P60HL-23282-01 0001 (SRC) DAVIDSON, EZRA C. Comprehensive
hospital/community sickle cell center -Fctoscopy for intrauterine diag-
nosis of hemoglobinopathy (human, monkeys),
P60HL-23282-01 0002 (SRC) EDMONDS, S RANDOLPH. Comprehensive
hospital/community sickle cell center -Clinical evaluation of alternate
pathaway of compliment activation.
P60HI-23282-01 0003 (SRC) KELLY, A PAUL. Comprehensive hospital/community
sickle cell center -Treatment of sickle cell ulcers with physical therapy
and vitamin E (human).
P60HI-23282-01 0004 (SRC) FIALA, MILAN. Comprehensive hospital/community
sickle cell center-Bacterial, viral and mycoplasmal infections and
sickle cell disease complications.
P60HI-23282-01 9001 (SRC) SATCHER, DAVID. Comprehensive
hospital/community sickle cell center-Core -Institutionalization of edu-
cation, screening and counseling.
PROJECT NUMBER AND INVESTIGATOR ADDRESS
P60Hl.23282.01 9002 (SRC) BRANCH. GERAIDINE. Comprehensive
hospital/community sickle cell center-Core-Model sickle cell service
for neighborhood health centers.
-01 (CVB) OVERBECK, HENRY W, UNIVERSITY OF AUBAMA CAR-
DiOVASCUUR RES & TRNG CTR , BIRMINGHAM, ALA. Hemodynamics
and vasoactivity in renal hypertension (human, dogs)
"°'.J??*^'^' HAYNES, DUNCAN H, UNIVERSITY OF MIAMI, DEPART-
MENT OF PHARMACOLOGY, MIAMI, FLA. Membrane binding and trans-
port of calcium and potassium ionophores.
■01 (SRC) FRANZBLAU, CARl, BOSTON UNIVERSITY, 80 EAST CON-
CORD STREET, BOSTON, MASS. Pulmonary vascular smooth muscle
cell dynamics (rat, rabbit).
"Inimrl' ^'^"TENSTEIN, LAWRENCE M, GOOD SAMARITAN
HOSPITAL, 5601 LOCH RAVEN BOULEVARD, BALTIMORE MO Phar-
macologic control of hypersensitivity phenomena (human)
•01 (PBC) REDDY, YERRADHODDI S, UNIVERSITY OF TEXAS MED
SCH, 6431 FANNIN; MSMB 1222, HOUSTON, TEX. Phosphorylation of
myocardial protein (guinea pigs).
•01 (EVR) HIGHTOWER, LAWRENCE E, UNIVERSITY OF CONNEC-
TICUT, MICROBIOLOGY SECTION, BOX U-44, STORRS, CONN. NOV infec-
tion-Analysis at the subcellular level (chickens).
01 (CTY) lAGUNOFF, DAVID, UNIVERSITY OF WASHINGTON DE-
PARTMENT OF PATHOLOGY, SM-30, SEATTLE, WASH. Mast' cell
granules -Structure and secretion (rats).
01 (PTHA) KIEINERA(\AN, JEROME I, MOUNT SINAI SCHOOL 1
GUSTAVE L LEVY PUCE, NEW YORK, N Y. Experimental emphysema-
Depression of protease inhibitors (rats, hamsters).
01 (NTN) DUPONT, JACQUEUNE, IOWA STATE UNIVERSITY DEPT
OF FOOD AND NUTRITION, AMES, IOWA. Dietary fat, cholesterol and
bile acid turnover (rats).
•01 (CVB) SCHERIAG, BENJAMIN J, VETERANS ADMINSTRATION
HOSP, 921 N E 13TH, OKLAHOMA CITY, OKLA. Mechanisms of ischemic
rhythm disorders (dogs).
-01 (CVB) OVERBECK, HENRY W, UNIVERSITY OF ALABAMA
UNIVERSITY STATION, BIRMINGHAM, AU, Ions, water, and hypertension
(human, dogs, rats).
-01 (PHY) FARBER, JAY P, UNIVERSITY OF OKLAHOMA P 0 BOX
26901, OKUHOMA CITY, OKLA. Early hypoxia and development of
respiratory control.
•01 (CVB) FERRIS, THOMAS F, UNIVERSITY OF MINNESOTA 420
DELAWARE STREET, S E, MINNEAPOLIS, MINN. Physiology of renin al-
dosterone and prostaglandin (human, rats, dogs).
•01 (PTHA) WIENER, JOSEPH, WAYNE STATE UNIVERSITY 540 EAST
CANFIELO, DETROIT, MICH. Morphogenesis of hypertensive vascular
disease (rats).
•01 (CVA) MC CUSKEY, ROBERT S, WEST VIRGINIA UNIVERSITY DE-
PARTMENT OF ANATOMY, MORGANTOWN, W VA. Hepatic microvascular
regulatory mechanisms (rat).
•02 (PHY) TWAROG, BETTY M, STATE UNIVERSITY OF NEW YORK
DEPARTMENT OF ANATOMICAL SCIS . STONY BROOK, N Y. Pharmacolo-
gy of relaxation in smooth muscle (mollusks),
-01 (BBCB) HARTSHORNE, DAVID J, UNIVERSITY OF ARIZONA 309
AGRICULTURAL SCIENCES BLDG, TUCSON, ARIZ. Biochemistry of' con-
tractile proteins (chicken, rabbit).
-01 (SGYA) IIU, MAW-SHUNG, BOWMAN GRAY SCHOOL DEPT OF
PHYSIOLOGY & PHARMA, WINSTON-SALEM, N C. Substrate metabolism
in isolated myocytes in shock (dogs, rats, guinea pigs)
■01 (CVA) GETTES, LEONARD S, UNIVERSITY OF NORTH CAROLINA
338 CLINICAL SCIS BLDG 229H, CHAPEL HILL, N C. Effect of drugs on
ischemic cardiac cells (dogs, guinea pigs, pigs).
•01 (CVA) CUTILLETTA, ANTHONY F, JOHN HOPKINS HOSPITAL 600
NORTH WOLFE STREET, BALTIMORE, MD. A study of the regulation of
myocardial hypertrophy (rats).
•01 (IMS) BLUMENTHAL, MALCOLM N, UNIVERSITY OF MINNESOTA
BOX 434, MINNEAPOLIS, MINN. Immunogenetic factors in allergic
respiratory diseases (human).
-01 (CVA) DIANA, JOHN N, LOUISIANA STATE UNIVERSITY & 3 BOX
33932, SHREVEPORT, LO. Protection of the ischemic myocardium
(dogs).
■01 (IMS) SCHANFIELD, MOSES S, AMERICAN NATIONAL RED
CROSS, 1730 E ST N W, WASHINGTON, D C. Selected topics on blood
transfusion (rabbits, human).
■01 (PHRA) SHAND, DAVID G, DUKE UNIVERSITY, BOX 3813, DUR-
HAM, N C. Treatment of ventricular arrhythmias with propranolol
(human).
■04 (HEM) FUHR, JOSEPH E, UNIVERSITY OF TENNESSEE 1924
ALCOA HIGHWAY, KNOXVILLE, TENN. Sickle cell anemia and
hemoglobin synthesis (monkeys).
'.01 (SGYB) VROMAN, LEO, DOWNSTATE MEDICAL CENTER 450
CLARKSON AVENUE, BROOKLYN, N Y. Flow and flexing at
blood/biomaterial interfaces,
1-01 (CVB) HOCHMUTH, ROBERT M, DUKE UNIVERSITY, BIOMEDICAL
ENGINEERING DEPT, DURHAM, N C. Mechanical measurement of cell
membrane viscosity (human),
•06 (MET) SABESIN, SEYMOUR M, UNIVERSITY OF TENNESSEE 951
COURT AVE, ROOM 335M, MEMPHIS, TENN Pathologic effects on'cells
of modified lipoproteins (rats, human)
-01 (CVA) DOUGLAS, WILLIAM H, TUFTS UNIVERSITY 136 HAR
RISON AVENUE, BOSTON. MASS Surfactant synthesis by type II cells
in vitro (rats)
I.0I (SRC) SINGH, BRAMAH N. WADSWORTH VA HOSPITAL SAW
TELLE i WILSHIRE BOULEVARDS, LOS ANGELES, CALIF Mechanisms
and control o( sudden cardiac death (human, dog)
i-01 (PHRA) BERMAN, WILLIAM, JR, UNIVERSITY OF NEW MEXICO
DEPARFMENT OF PEDIATRICS, ALBUQUEROUE, N MEX Effects of digox-
in therapy in newborn and adult sheep
-01 (PTHA) RYAN, STEPHEN F, SI LUKES INSTITUTE FOR HEALTH
AMSTERDAM AVENUE « 114TH ST, NEW YORK, N Y Acute alveolar m-
lury (dogs)
.01 (CVA) CASE, ROBERT B, ST LUKES HOSPITAL, AMSTERDAM
AVENUE S 114TH ST, NEW YORK, N Y. Control of coronary flow by car-
bon dioxide tension (dogs).
■01 (RAD) PIERSON, RICHARD N, JR, ST LUKE'S HOSPITAL AM-
STERDAM AVENUE & I14TH ST, NEW YORK, N Y. Quantitative radiocar-
diography (human, dogs).
ROlHl-23312
R01HL-23392
R01HL-23S42
R01HL-23586'
R01HL-23S87-
R01HL-23S88
ROlHL-23593
R01HL-23S95-
R01HL-23S98-
R01HL-23599-
R01HL-23600
R01HL-23601
ROlHL-23602.
ROlHL-23603-
R01HL-23604
ROIHL-23614
R0IHL-2361S
ROIHL-23618-
R01HL-23624
ROlHL-23626
R01HL.23631-
ROlHL-23653
R01HL-23654
ROlHL-23726
ROlHL-23736-
R01HL.23899
R0IHL.23900
R01HL-2394S
R01HL-23969
ROIHL.23970
ROIHl.23980
R0IHL.23981
ROIHl.23982
R01H1.23983-
582
ROlHl.23985-01 (CVA) MINH, VU-DINH, UNIVERSITY OF CALIFORNIA, CALIFORNIA
COLLEGE OF MEDICINE, IRVINE. CALIF. Role of the diaphragm in re-
gional lung mechanics (dogs).
ROlHl-23990-Ol (PHRA) STULL, JAMES T, UNIVERSITY OF TEXAS, 5323 HARRY
HINES BLVD, DALLAS, TEX. Role of phosphoprotein in cardiac inotropic
responses.
R01HL.23994-01 (PBC) BHAM, ASHOK K, WAYNE STATE UNIVERSITY 540 E CAN-
FIELD AVENUE, DETROIT, Ml. Biochemical properties of human cardiac
myosin.
ROlHL-24021.02 (HEM) SHAEFFER, JOSEPH R, CENTER FOR BLOOD RESEARCH
800 HUNTINGTON AVENUE, BOSTON. MASS. Erythocyte membrane sulf-
hydrls and Rh activity (human).
ROlHL-24048-01 (SSS) CHAN, lEE-NIEN I, UNIVERSITY OF TEXAS DEPT OF
HUMAN BIOLOGICAL, GALVESTON. TEX. Regulation of hemoglobin
synthesis in chick embryos.
NOlHR-32900-09 (HCRG) BURST, SANIA, PORTLAND, OREGON. Pilot study to
standardize the measurement of 'closing volume' (human)
NOlHR-32902-07 (HCRG) MACKLEN, P T, MONTREAL, CANADA Pilot study to
standardize the measurement of closing volume (human)
NOlHR-32903-11 (HCRG) CHERNIACK, R M, MANITOBA, CANADA Pilot study to
standardize the measurement of 'closing volume' (human)
N01HR-S29S7-02 (HCRG) BOAT, THOMAS F, CLEVELAND, OHIO Composition of
respiratory mucus (human, swine).
NOlHR.62901-04 (HCRG) FREDBERG, JEFFREY J, CAMBRIDGE, MASSACHUSEHS
Measure pulmonary function In infants and children (also dogs rab-
bits).
N0IHR.629I0-02 (HCRG) SOBIN, SIDNEY S, LOS ANGELES, CALIFORNIA.
Fibroprotein networks of pulmonary alveolar wall (human)
NOlHR.62920-02 (HCRG) REEVES, JOHN T, DENVER, COLORADO Noninvasive
diagnosis of pulmonary hypertension (dog, human)
NOlHR.62930-03 (HCRG) HAY, ROBERT J, ROCKVILLE, MARYLAND. Lung cell
resource facility.
N01HR-62931.02 (HCRG) HISS, ROLAND, ANN ARBOR, MICHIGAN Development
and evaluation of continuing education in pulmonary medicine
NOlHR.62934-02 (HCRG) HARDY, JANET B, BALTIMORE, MARYLAND Evaluate
continuing education in pulmonary medicine
N01HR-6293S.02 (HCRG) TURNER-WARWICK, MARGARET, LONDON, EN
GLAND Histocompatibility antigens-Evolution of respiratory hypersen-
sitivity (human).
N01HR.62942.04 (HCRG) PETTY, THOMAS L, DENVER, COLORADO Nocturnal ox
ygen therapy in chronic hypoxic lung disease (humam)
N01HR.62943-0S (HCRG) ANTHONISEN, NICHOLAS R, WINNIPEG, CANADA
Nocturnal oxygen therapy in chronic hypoxic lung disease (human)
NOlHR.62944-04 (HCRG) KVAIE, PAUL A, DETROIT, MICHIGAN Nocturnal oxygen
therapy in chronic hypoxic lung disease (human)
NOlHR-62945-04 (HCRG) CUGELl, DAVID W, EVANSTON, ILLINOIS Nocturnal ox-
ygen therapy in chronic hypoxic lung disease (human)
N01HR.62946-04 (HCRG) TIMMS, RICHARD M, U JOLU, CALIFORNIA. Nocturnal
oxygen therapy in chronic hypoxic lung disease (human)
NOlHR-62947-04 (HCRG) BOYLEN, C THOMAS, LOS ANGELES, CALIFORNIA. Noc
turnal oxygen therapy in chronic hypoxic lung disease (human)
NOlHR-62948-04 (HCRG) POOLE, KENNETH W, RESEARCH TRIANGLE PARK,
NORTH CAROLINA Evaluate antenatal steroid therapy in neonatal
respiratory distress syndrome.
NOlHR-62949-05 (HCRG) RIGATTO, HENRIQUE, WINNIPEG, CANADA Evaluate
antenatal steroid therapy in neonatal respiratory distress syndrome
N01HR-629S0-04 (HCRG) DEPP, RICHARD, EVANSTON, ILLINOIS Evaluate an
tenatal steroid therapy in neonatal respiratory distress syndrome
NOIHR.62951-04 (HCRG) BAUER, CHARLES, MIAMI, FLORIDA. Evaluate antenatal
steroid therapy in neonatal respiratory distress syndrome
N01HR-62952-0S (HCRG) ZACHMAN, RICHARD D, MADISON, WISCONSIN. Eval-
uate antenatal steroid therapy in neonatal respiratory distress syn-
drome.
NOlHR.72901-02 (HCRG) KRUEGER, DEAN E, WASHINGTON, DISTRICT OF
COLUMBIA. Study of intermittent positive pressure breathing (data
center).
NOlHR-72902-04 (HCRG) ANTHONISEN, NICHOLAS R, WINNIPEG, CANADA
Study of intermittent positive pressure breathing
NOIHR.72903.05 (HCRG) LEVIN, DAVID C, OKLAHOMA CITY. OKUHOMA, Study of
intermittent positive pressure breathing
NOlHR-72904-03 (HCRG) HODGKIN, JOHN E, LOMA LINDA. CALIFORNIA Study
of intermittent positive pressure breathing
N01HR.7290S.03 (HCRG) STEVENS, PAUL M, HOUSTON. TEXAS. Study of inter
mittent positive pressure breathing.
NOlHR-72906-03 (HCRG) HOPEWELL, PHILLIP C, SAN FRANCISCO. CALIFORNIA
Study of intermittent positive pressure breathing
N01HR.72920-01 (HCRG) DEARBORN, DORR G, CLEVEUND. OHIO Identify and
quantify cystic fibrosis factors (human)
NOlHR.72921-01 (HCRG) NELSON, THOMAS E, HOUSTON. TEXAS. Cystic fibrosis
factor identification and quantification (human)
NOlHR-72922-01 (HCRG) BOWMAN, BARBARA H, GALVESTON. TEXAS Cystic
fribrosis factor identication and quantification (human)
N01HR-72923-01 (HCRG) RENNERT, OWEN M, OKUHOMA CITY, OKUHOMA
Cystic fibrosis factor identification and quantification (human)
NOIHR.72972.01 (HCRG) CREER, THOMAS, DENVER, COLORADO. Self manage-
ment for asthmatic children
NOlHR-72973-01 (HCRG) FELDMAN, CHARLES H, NEW YORK, NEW YORK
Health education and attitudes of family toward asthmatic children
N01HR-72974-01 (HCRG) SHANNER, WILLIAM M, WASHINGTON, DISTRICT OF
COLUMBIA Self management systems for asthmatic children
NO1HV-12017-1S (HCRG) KRONICK, PAUL I, PHIUDELPHIA, PENNSYLVANIA
Fabrication of grafted hydrogel coatings lor plastic heart assist
devices.
NOIHV.12054-14 (HCRG) BURKEL, WILLIAM E, ANN ARBOR, MICHIGAN. Develop-
ment of intimal linings (human, cattle)
NOlHV-1 2060-1 8 (HCRG) MANSFIELD, PETER B, SEAHLE, WASHINGTON Tissue
cultured endothelium for vascular prosthetic devices (human
animals).
N01HV.1206S-16 (HCRG) POIRIER, VICTOR C, WALTHAM, MASSACHUSEnS.
Fabrication of implantable artificial heart devices (animals)
NOIHV-1 2 156-10 (HCRG) INSULl, WILLIAM, HOUSTON, TEXAS. Lipid research
clinic.
N01HV.I21S7-14 (HCRG) BIERMAN, EDWIN I, SEAHLE, WASHINGTON. Lipid
research clinic (human).
S83
PROJECT NUMBER AND INVESTIGATOR ADDRESS
N01HV-ialS«-IO (HCRO) KWITEROVICH, PETER O, nAIIIMORI MAKYIAND
Eslabhshmcnl ol .1 lipid lese.ifch clinic
N0IHV-t2IS9-09 (HCRO) SHEFFIELD. I THOMAS, BIRMINGHAM. AlABAMA lipid
restaich clinic
N01HV-iai60-1S (HCRO) STEINBERG. DANIEL, LA lOlLA. CAUFORNIA
Establishment ol a lipid reseaich clinic
N0IHV-I2434-1I (HCRO) HAMES. CURTIS O, CIAXION. GEORGIA Therapy tor
hypertension in the general population
N0)HV-1343S-)S (HCRO) CASTLE. CHARLES H, SAU LAKE CITY. UTAH Therapy
lor hypertension in the general population (human)
N01HV-17436-1S (HCRO) MAXWELL, MORTON H, LOS ANGELES. CALIFORNIA
Hypertension therapy in the general population (human)
N01HV-12440-I4 (HCRO) OBERMAN, ALBERT, BIRMINGHAM. ALABAMA Therapy
tor hypertension in the general population (human)
N01HV-H44J-14 (HCRO) HAWKINS. MORTON C, HOUSTON. TEXAS Therapy lor
hypertension in the general population (human)
N01HV-22913-09 (HCRO) ABBOUD. FRANCOIS M, IOWA CITY. IOWA Lipid
research clinic
N0IHV-229)4-08 (HCRO) KASHYAP, M L, CINCINNATI. OHIO Establishment ol a
lipid research clinic
N01HV-229IS-I1 (HCRC) FRANTZ, IVAN D, JR, MINNEAPOLIS. MINNESOTA
Establishment of lipid research clinic
N01HV-22916-16 (HCRG) SCHONFELD, GUSTAV, ST LOUIS. MISSOURI
Establishment ol a lipid research clinic
N01HV-22917-I1 (HCRG) LIHLE, ALICK, TORONTO. CANADA Lipid research clinic
(human)
NOIHV-22931-14 (HCRG) BLAUFOX, MORTON D, BRONX, NEW YORK Therapy
for hypertension in general population
NOlHV-22932-09 (HCRG) BRADFORD, REAGAN H. OKLAHOMA CITY.
OKLAHOMA Establishment of a lipid research clinic.
NOlHV-22937-07 (HCRG) BERMAN, REUBEN, MINNEAPOLIS. MINNESOTA.
Therapy for hypertension in general population
N01HV-22938-11 (HCRG) TUTTLE, ELBERT P, JR, ATLANTA. GEORGIA. Therapy (or
hypertension in general population.
N01HV-22939-12 (HCRG) JONES, JOHN W, EAST LANSING, MICHIGAN. Hyperten-
sion detection and follow-up program center
N01HV-2294S-11 (HCRG) BORHANI, NEMAT O, DAVIS. CALIFORNIA Cooperative
hypertension detection and lollow-up study (human).
NOlHV-22971-07 (HCRG) KJELSBERG, MARCUS, MINNEAPOLIS. MINNESOTA
Prevention of coronary heart disease (human).
NOlHV-22976-07 (HCRG) BLACKBURN, HENRY W, MINNEAPOLIS. MINNESOTA
Multiple risk factor intervention trial, prevention of coronarv heart dis-
ease
N01HV-22977-08 (HCRG) BORHANI, NEMAT O, DAVIS, CALIFORNIA. Intervention
trial for the prevention of coronary heart disease (human).
N01HV-22979-07 (HCRG) DALEN, JAMES E. CAMBRIDGE. MASSACHUSEHS. Inter-
vention trial for the prevention of coronary heart disease (human).
N01HV-22980-06 (HCRG) SHERWIN, ROGER W, BALTIMORE. MARYLAND Inter-
vention trial for the prevention of coronary heart disease (human).
N01HV-2298)-IO (HCRG) HULLEY, STEPHEN B, SAN FRANCISCO. CALIFORNIA In
tervention trial for the prevention of coronary heart disease (human).
N01HV-22982-07 (HCRG) ZIMMERMAN, HERBERT B, ST LOUIS, MISSOURI. In
tervention trial for prevention of coronary heart disease (human)
NOIHV-22983-07 (HCRG) WYNDER, ERNST L, NEW YORK. NEW YORK. Interven-
tion trial for the prevention of coronary heart disea.se (human).
N01HV-32913-n (HCRG) YASUDA, HIROTSUGU K, RESEARCH TRIANGLE PARK.
NORTH CAROLINA. Study electrodeless glow discharge for modifying
polymer surface.
N01HV-329 17-08 (HCRG) NYILAS, EMERY, EVEREH. MASSACHUSETTS. Materials
development and testing.
NOIHV.32919.12 (HCRG) AISENBERG, SOL, SOUTHFILED. MICHIGAN. Material
development and testing heparinization processes.
NOIHV-32931-09 (HCRG) LA ROSA, JOHN C, WASHINGTON. DISTRICT OF
COLUMBIA. Establishment of a lipid research clinic center.
NOlHV-32933-07 (HCRG) MOLTENI, AGOSTINO, CHICAGO. ILLINOIS. Hyperten-
sion detection and follov«-up program central laboratory (human).
NOIHV-32949-11 (HCRG) BERRY, GUY C, PITTSBURGH. PENNSYLVANIA. Modifica-
tion of silicon elastomers for medical devices.
N01HV-329S0-08 (HCRG) KWIATKOWSKI, G. T., BOUND BROOK, NEW JERSEY
Blood compatible poly-electrolyles.
N01HV-32953-10 (HCRG) BAIER, ROBERT E, BUFFALO, NEW YORK. Materials
compatible with blood (dogs).
N0IHV-329S9-10 (HCRG) BRAUMAN, SHARON K, MENLO PARK. CALIFORNIA.
Development of materials for heart assist devices.
NOlHV-32973-12 (HCRG) FISHER, llOYD 0, SEATTLE. WASHINGTON. Coordinating
center for collaborative studies on coronary artery surgery.
NOIHV-32974-09 (HCRG) ALDERMAN, EDWIN I, STANFORD, CALIFORNIA. Col-
laborative studies on coronary artery surgery (human).
N01HV-32975-08 (HCRG) JUDKINS, MELVIN P, LOMA LINDA. CALIFORNIA. Col-
laborative studies on coronary artery surgery (human).
N01HV-32976-09 (HCRG) GLASSMAN, EPHRAIM, NEW YORK. NEW YORK. Col-
laborative studies on coronary artery surgery (human).
NOlHV-32978-08 (HCRG) KEMP, HARVEY G, NEW YORK, NEW YORK. Collabora-
tive studies on coronary artery surgery
N01HV-32979-09 (HCRG) GOSSELIN, ARTHUR J, MIAMI BEACH, FLORIDA Col-
laborative studies on coronary artery surgery
N01HV-32980-07 (HCRG) KAISER, GEORGE C, ST LOUIS. MISSOURI. Collabora-
tive studies on coronary artery surgery (human),
N01HV-3298I-10 (HCRG) SAUTTER, RICHARD D. MARSHFIELD. WISCONSIN. Col
laborative studies on coronary artery surgery (human)
NOIHV-32983-n (HCRG) BOURASIA, MARTIAL B. MONTREAL. QUEBEC Col
laborative studies on coronary artery surgery (human)
N01HV-32984-10 (HCRG) FRYE. ROBERT C, ROCHESTER. MINNESOTA Collabora-
tive studies on coronary artery surgery (human)
N01HV-3298S-n (HCRG) MUNDTH. EIDRED D. BOSTON. MASSACHUSETTS Col-
laborative studies on coronary artery surgery (human)
N0IHV-33I0I-06 (HCRG) WIDDOWSON. GRAHAM. SAN FRANCISCO. CALIFOR-
NIA- Development and conduct of a multiple risk factor intervention
trial (human).
NOIHV-33 105-09 (HCRG) WILD, J E, OAKLAND. CALIFORNIA. Intervention trial for
prevention of coronary heart disease (human)
NOIHV-33 106-06 (HCRG) DAWBER, THOMAS R, BOSTON. MASSACHUSEHS In-
tervention trial for the prevention of coronary heart disease (human).
NOIHV-33 108-04 (HCRG) KEZDI, PAUL, KETTERING. OHIO. Prevention of coronary
heart disease (human).
N01HV-33I0904 (HCRG) KUllER, LEWIS H. PIHSBUIKiH l'( NN',YI VANIA Inl.r
venlion I11.1I (or the prevention ol coronary heart di%ea\e (human)
NOIHV.33nO.O4 (HCRO) HOUiAES. WIlllAM I. PHIIAOFI PHIA. PFNNSYtVANIA
Prevention ol coronary heart dr.ease (human)
N01HV-42902-08 (HCRG) CARCIA-PAIMIERI, MARIO R, SAN lUAN PUERTO
RICO Epidemiological studies of coronary heart disease (human)
N0IHV.429I 1-07 (HCRG) RAUTAHARJU, P M, HALIFAX. CANADA ECC center loi
prevention ol coronary heart disease (human)
NOIHV-42914-13 (HCRG) PORTNER, PEER M, BfRKELEY. CALIFORNIA Solenoid
left ventricular assist system (cattle)
N01HV. 42928. 07 (HCRG) HAUBOID, A D, SAN DIEGO. CALIFORNIA Continued
development ol carbon lilm deposits lor prosthetics
N01HV-42929-08 (HCRG) JACOBSON, HOWARD N, PISCATAWAY. NEW lERSEY
Risk lactor intervention trial lor the prevention ol CHD (human)
N01HV.42930-09 (HCRG) SCHOENBERGER, JAMES A, CHICAGO. ILLINOIS Risk
lactor intervention trial lor the prevention ol CHO (human)
N01HV-42931-07 (HCRG) MARMORSTON. JESSIE, LOS ANGELES. CALIFORNIA
Risk lactor intervention trail for the prevention of CHD (men)
N01HV.42932-0S (HCRG) GIESE, WARREN K, COLUMBIA. SOUTH CAROLINA Risk
factor intervention trial lor the prevention ol CHO (human)
N01HV-42933-09 (HCRG) CHRISTAKIS, GEORGE, MIAMI. FLORIDA Multiple risk
factors in coronary heart disease (human)
NOlHV-42960-07 (HCRG) NOSE, YUKIHIKO, CLEVELAND. OHIO Development and
evaluation of cardiac prostheses (calves)
N01HV-42961-06 (HCRG) NYILAS, EMERY, EVEREH. MASSACHUSETTS Evalua-
tion of biomaterials in contact with blood (dogs)
N01HV-42969-06 (HCRG) YANNAS, lOANNiS V, CAMBRIDGE. MASSACHUSETTS
Interactions ol natural and chemically modified biopolymers with
blood (dogs)
N01HV-42984-0S (HCRG) MICHAEll, DOV, SAN FRANCISCO. CALIFORNIA Interac-
tions ol modified biopolymers with blood (humans, rats)
N01HV-52901-06 (HCRG) KROl, WILLIAM F, BALTIMORE. MARYLAND. Aspinn-
myocardial infarction study
N01HV-S2907-04 (HCRG) SIIBERBERG, ALEXANDER, REHOVOT. ISRAEL In
teractions of platelets with collagens (human, mammals).
N01HV-S2941-04 (HCRG) RIOS, JORGE, WASHINGTON, DISTRICT OF COLUMBIA.
Center for aspirin-myocardial infarction study (human).
N01HV-S2966-01 (HCRG) GRIFFIN, PAUL M, SCHENECTADY. NEW YORK. Develop
ment and evaluation of an ultrasonic imaging system (swine)
N01HV.52971-06 (HCRG) DAWBER, THOMAS R, BOSTON. MASSACHUSEHS
Reexamination of Framingham heart study cohort.
N01HV-S3006-06 (HCRG) NORMAN, JOHN C. HOUSTON. TEXAS Evaluation ol
model VII left ventricular assist device (human).
N01HV-S3008-07 (HCRG) KEISER, JOHN M, WALTHAM. MASSACHUSETTS Lett
ventricular assist device-Clinical evaluation (human).
N01HV-S301O-03 (HCRG) HRUBEC, ZDENEK, WASHINGTON. DISTRICT Of COLUM
BIA. NAS-NRC twin registry.
N01HV-53O15-09 (HCRG) STEIN, YECHEZKIEL, JERUSALEM, ISRAEL Establish
ment of a lipid research clinic (human).
N01HV-53027-OS (HCRG) KAPLAN, EDWARD M, BOSTON. MASSACHUSEHS
Data coordinating center for the unstable angina pectoris study
N01HV-S3029-04 (HCRG) CLARKSON, THOMAS B, WINSTON SALEM. NORTH
CAROLINA. Nonhuman primate models of atherosclerosis
N01HV-53030-0S (HCRG) MC GILL, HENRY C, SAN ANTONIO, TEXAS. Nonhuman
primate models of atherosclerosis and hypertension.
N01HV-53031-04 (HCRG) GARD, ELIZABETH, KENSINGTON, MARYLAND Nonhu
man primate models of atherosclerosis and hypertension.
N01HV-62900-00 (HCRG) LABARTHE, DARWIN R, ROCHESTER. MINNESOTA.
Study of breast cancer and reserpine use (human).
N01HV-6290S-02 (HCRG) ANGEIAKOS, EVANGELOS T, PHILADELPHIA.
PENNSYLVANIA. Non-human primate models of arteriosclerosis.
N01HV-62911-04 (HCRG) DANIELS, A V, SALT LAKE. UTAH. Vena cava ring tests
of biomaterials in dogs.
N01HV-6294I-01 (HCRG) GRAMBSCH, P VICTOR, MINNEAPOLIS, MINNESOTA.
Nutrition coding center for MRFIT and LRC programs.
N01HV-62955-04 (HCRG) STEMMERMANN, GRANT N, HONOLULU. HAWAII
Data collection in clinical pathology and morbid anatomy (men).
N01HV-62957-0S (HCRG) MEINERT, CURTIS L, BALTIMORE. MARYLAND. Coor
dinating center model for NHLI clinical trials.
N01HV-62960-00 (HCRG) MUELLER, GILTRUD, ST LOUIS. MISSOURI. Techniques
to protect ischemic myocardium and minimize infant size (human).
NOIHV-62969-03 (HCRG) GORDON, MICHAEL S, MIAMI. FLORIDA Cardiology
patient simulator evaluation.
N01HV-7291S-02 (HCRG) SIOTKOFF, LAWRENCE M, WASHINGTON. DISTRICT OF
COLUMBIA. Therapy for hypertension in the general population.
N01HV-72917-00 (HCRG) UCHIDA, IRENE A, ONTARIO. CANADA. Plasma
lipoproteins in identical twins.
N01HV-72918-01 (HCRG) MC MILLIN, CARL R, DAYTON. OHIO. Test polymers for
circulatory assist devices.
N01HV-729I9-0I (HCRG) KAROOS, J L, ST. LOUIS. MISSOURI Test polymers (or
circulatory assist divices.
N01HV-72924-04 (HCRG) OLINGER, CHARLES P, CINCINNATI. OHIO Noninva-
sive detection of atherosclerotic lesions (human, animals).
N01HV-7292S-04 (HCRG) MC HENRY, lAWRENCEC, WINSTON SALEM, NORTH
CAROLINA. Non-invasive detection of atherosclerotic lesions (human,
monkeys, dogs).
NOIHV-72926-04 (HCRG) REID, JOHN M, SEATTLE. WASHINGTON Ultrasonic
imaging development
N01HV-72927-00 (HCRG) BARBER, FRANK F, CAMBRIDGE. MASSACHUSETTS
Systems for noninvasive detection of atherosclerotic lesions (human)
NOIHV-72928-04 (HCRG) EVANS, TITUS C, ROCHESTER. MINNESOTA Develop
high resolution ultrasonic imaging techniques
N01HV-72929-01 (HCRG) FOX, MARTIN, STORRS. CONNECTICUT Improved detec
tion of atherosclerosis (human, dogs)
NOIHV-72930-02 (HCRG) BIANKENHORN, DAVID H, LOS ANGELES. CALIFOR
NIA. Atherosclerosis assessment-Angiography and ultrasound (dogs,
human).
NOIHV-72931-02 (HCRG) OVITT, THERON W, TUCSON. ARIZONA Noninvasive
detection of atherosclerotic lesions (human, dogs)
N01HV-72932-00 (HCRG) SASHIN, DONALD, PITTSBURGH. PENNSYLVANIA Non-
invasive detection of atherosclerotic lesions (human, phantoms).
N01HV-72933-01 (HCRG) PORTNER, PEER M, BERKELEY. CALIFORNIA Electrical
energy transmission technique development (dogs).
N01HV-72934-01 (HCRG) WHAIEN, ROBERT L, WALTHAM. MASSACHUSETTS.
Development of a left heart assist blood pumps (human, cattle).
PROJECT NUMBER AND INVESTIGATOR ADDRESS
584
I
N01HV-72936
NOIHV-72937
N01HV-72938
N01HV-72939
NOIHV-72940
N01HV-72941
N01HV-72942
N01HV-72943
N01HV-72944
NOIHV-72945
N01HV-72946
N01HV-72948-
NOlHV-72949-
N0JHV-729SO
N01HV-72951
NOlHV-72952
NOtHV-72953
N01HV.729S4.
N01HV.729SS-
N01HV-729S6
N01HV-729S7
NOlHV-72958
N0)HV-72959-
N01HV-72960
N01HV-72961
N01HV-72963
N01HV-72964
N01HV-72965
N01HV-72966
N01HV-72967
N01HV-72968
N01HV-72969.
NOIHV-72970-
N01HV.72971
N01HV-72975
NOJHV-72976
N01HV.72978
N01HV.72979
N01HV-72980
N01HV-72983
N0)HV-72984
NOIHV-72986
NOIHV-72987
NOlHV-72989
N01HV-72990
N01HV-81388
N0IHV.82900.
NOIHV-82901-
NOIHV-82902
NOIHV-82903
NOIHV-82904
-00 (HCRG) NORMAN, JOHN C, HOUSTON, TEXAS Left heart
assist device development (human, cattle)
■00 (HCRG) LEDERMAN, DAVID, EVEREH, MASSACHUSETTS Left
heart assist blood pumps (calves).
■OJ (HCRG) PORTNER, PEER M, BERKELEY, CALIFORNIA. Develop-
ment of a left heart assist blood pump
■01 (HCRG) BUCK, KEITH S, EMERYVILLE. CALIFORNIA. Develop and
evaluate left heart assist blood pumps (human, calves pigs)
"cArunfr^fo',""*"'^^*^''' EUGENE B. CAMBRIDGE, MAS-
bALHUbtrrs. Therapy to protect ischemic myocardium (human)
-02 (HCRG) SOBEl, BURTON E, ST. LOUIS, MISSOURI. Therapy to
protect ischemic myocardium-Clinical tests
-02 (HCRG) WIUERSON, JAMES T, DALLAS. TEXAS. Therapy to
protect ischemic myocardium-Clinical tests
-01 (HCRG) FREER, RICHARD J, RICHMOND, VIRGINIA. Prostaglan-
din and kallikrcin kinin system antagonists.
-02 (HCRG) MARSHAll, GARLAND R, ST LOUIS, MISSOURI
Prostaglandin and kallikrein kInin antagonists
■03 (HCRG) NEEDIEMAN, PHILIP, ST LOUIS, MISSOURI. Develop
prostaglandin synthesis and receptor antagonists.
■02 (HCRG) STEWART, JOHN M, DENVER, COLORADO. Develop
ment of kallikrein-Kinin system antagonists
-03 (HCRG) HAWKINS, MORTON C, HOUSTON, TEXAS. Coordinat-
ing center for propranolol heart trial (human).
-03 (HCRG) CROW, RICHARD S, ST. PAUL, MINNESOTA ECG
center for proprancolo heart trial.
-02 (HCRG) IBBOTT, FRANK A, VAN NUYS, CALIFORNIA. Central
laboratory for propranolol heart trial.
-03 (HCRG) VOKONAS, PANTEL S, BOSTON, MASSACHUSEHS
Clinical center for propranolol heart trial (human)
■02 (HCRG) KOHN, ROBERT M, ALBANY, NEW YORK. Clinical
center for propranolol heart trial (huamn).
-04 (HCRG) MATHEWS, lOUIS B, HANOVER, NEW HAMPSHIRE
Clinical center for propranolol heart trial.
-06 (HCRG) BORHANI, NEMAT O, DAVIS, CALIFORNIA. Clinical
center for propranolol heart trial (human).
-02 (HCRG) GARYN, WIINER, EVANSTON, ILLINOIS. Clinical center
for propranolol heart trial (human),
■02 (HCRG) MC NAMARA, J JUDSON, HONOLULU, HAWAII. Clini-
cal center for propranolol heart trial (human).
■02 (HCRG) BRENEMAN, GERALD M, DETROIT, MICHIGAN. Chnical
center for propranolol heart trial (human).
-02 (HCRG) HOUAES, WILLIAM L, PHIUOELPHIA, PENNSYLVANIA
Clinical center for propranolol heart trail (human).
-04 (HCRG) KRAMER, ROBERT J, NEW HYDE PARK, NEW YORK.
Clinical center for propranolol heart trial (human)
■02 (HCRG) LICHSTEIN, EDGAR, BROOKLYN, NEW YORK. Clinical
center propranolol heart trial (human).
-03 (HCRG) RANHEIM, PHILLIP J, MINNEAPOLIS, MINNESOTA. Clini-
cal center for propranolol heart trial.
■02 (HCRG) HARING, OIGA M, EVANSTON, ILLINOIS. Clinical
center for propranolol heart trial (human).
■02 (HCRG) GREGORY, JOHN J, SUMMIT. NEW JERSEY. Clinical
center for propranolol heart trial (human).
-02 (HCRG) MAURICE, GORDON I, PORTUND, OREGON. Clinical
center for propranolol heart trial.
-03 (HCRG) YU, PAUL N, ROCHESTER, NEW YORK. Clinical center
for propranolol heart trial.
-02 (HCRG) SCHOENBERGER, JAMES A, CHICAGO. ILLINOIS
Clinical center for propranolol heart trial (human).
■03 (HCRG) KUO, PETER T, PISATAWAY. NEW JERSEY. Clinical
center for propranolol heart trial.
•02 (HCRG) BARKER, ALLEN H, SALT LAKE CITY, UTAH. Clinical
center for propranolol heart trial (human).
04 (HCRG) HAYWOOD, L JULIAN, LOS ANGELES, CALIFORNIA.
Clinical center for propranolol heart trial (human).
-01 (HCRG) MOISE, JOHN C, SACRAMENTO, CALIFORNIA. Energy
converters to control heart assist devices (human, cattle)
-02 (HCRG) JARVIK, ROBERT K, SALT LAKE CITY, UTAH. Energy
converter for left ventrical assist devices (calves).
-02 (HCRG) KEISER, JOHN M, WALTHAM. MASSACHUSEHS. Energy
converters to control heart assist devices (human, cattle).
-02 (HCRG) ClARKSON, THOMAS B, WINSTON SALEM, NORTH
CAROLINA. Development of models of hypertension.
-01 (HCRG) POOLE, KENNETH W, RESEARCH TRIANGLE PARK,
NORTH CAROLINA. Therapy to protect ischemic myocardium -Data
Center.
■02 (HCRG) HERD, JAMES A, CAMBRIDGE, MASSACHUSEHS.
Development of models of hypertension.
-00 (HCRG) SCHROTT, HEUWUT G, IOWA CITY, IOWA. Nutrition
counseling in hyperlipidemia.
■03 (HCRG) OSTFEID, ADRIAN M, HARTFORD, CONNECTICUT. High
blood pressure control program (human).
-02 (HCRG) SOUTHARD, JOHN W, BALTIMORE, MARYLAND. High
blood pressure control program (human).
-02 (HCRG) MC CALLUM, DAVID B, COLUMBIA, SOUTH CAROLINA.
High blood pressure control program (human).
-02 (HCRG) OLIVER, CHARLES G, DALLAS, TEXAS. High blood pres
sure control program (human).
-00 (HCRG) KLEIN, DAVID H, CHICAGO, ILLINOIS High blood pres-
sure control program (human).
-20 (HCRG) BEACH, WILLIAM F, BOUND BROOK, NEW JERSEY.
Microfiber substrate for growth of intimal linings in circulatory assist
devices .
-03 (HCRG) MILLER, RICHARD R, HOUSTON, TEXAS. Clinical center
for propranolol heart trial (human).
-02 (HCRG) PETERS, ROBERT W, SAN FRANCISCO, CALIFORNIA.
Clinical center for propranolol heart trial (human).
■02 (HCRG) SCHLANT, ROBERT D, ATLANTA, GEORGIA. Clinical
center for propranolol heart trial (human).
■02 (HCRG) LAUBACH, CHARLES A, DANVILLE, PENNSYLVANIA.
Clinical center for propranolol heart trial (human).
■02 (HCRG) PROUT, THAODEUS E, BALTIMORE, MARYLAND. Clini-
cal center for propranolol heart trial (human).
NOIHV
N01HV
NOIHV
NOIHV-
NOIHV-
NOIHV-
N01HV-
NOIHV-
NOIHV-
-8290S
■82906
■82907
■82908
■82909
>82910<
'82913-
82915-
82919^
■02 (HCRG) G ROVER, JOHN, OAKUND, CALIFORNIA. Clinical
center for propranolol trial (human).
-02 (HCRG) RICHARDSON, DAVID D, RICHMOND. VIRGINIA Clini-
cal center for propranolol heart trial (human).
-02 (HCRG) CANOSA, FRANK L, MIAMI BEACH, FLORIDA Clinical
center for propranolol heart trial (human).
-02 (HCRG) CAPONE, ROBERT J, PROVIDENCE, RHODE ISLAND
Clinical center for propranolol heart trial (human).
■02 (HCRG) GAZES, PETER C, CHARLESTON, SOUTH CAROLINA
Clinical center for propranolol heart trial (human).
■00 (HCRG) THEROUX, PIERRE A, MONTREAL, QUEBEC, CANADA.
Clinical center for propranolol heart trial (human).
■00 (HCRG) ERFURT, JOHN C, ANN ARBOR, MICHIGAN. Demonstra-
tion programs in hypertension control In the work setting (human)
■01 (HCRG) KASS, EDWARD H, BOSTON, MASSACHUSEHS. Therapy
for hypertension in the general population (human).
00 (HCRG) DALY, BENEDICT D T, BOSTON. MASSACHUSEHS.
Development of percutaneous energy transmission systems.
»
^^^ssm
ABBOUD. FRANCOIS M
ABBOUD. FRANCOIS M
ABBOUD, FRANCOIS M
ABBOUD, FRANCOIS M
ABBOUD. FRANCOIS M
ABBOUD, FRANCOIS M
ABBOUD. FRANCOIS M
ABBOUD, FRANCOIS M
ABBOUD, FRANCOIS M
ABBOUD, FRANCOIS M
ABBOUD. FRANCOIS M
ABBOUD, FRANCOIS M
ABBOUD, FRANCOIS M
ABBOUD. FRANCOIS M
ABBOUD. FRANCOIS M
ABBOUD, FRANCOIS M
ABBOUD, FRANCOIS M
ABBOUD, FRANCOIS M
ABBOUD. FRANCOIS M
ABBOUD, FRANCOIS M
ABBOUD. FRANCOIS M
ABBOUD. FRANCOIS M
ABBOUD. FRANCOIS M
ABBOUD, FRANCOIS M
ABEL, GENE G
ABELMANN, WALTER H
ABELMANN, WALTER H
ABELMANN, WALTER H
ABILDGAARD, CHARLES
ABILDSKOV, J A
ABILDSKOV, J A
ABRAHAM'SHRAUNER. B
ABRAHAM. JERROLD L
ABRAMS, HERBERT L
ABRAMS, HERBERT L
ABRAMS, HERBERT L
ABRAMSON. FRED P
ABSHER, P MARLENE
ACKERMAN, EUGENE
ACOSTA. DANIEL, JR
ACTON, RONALD T
ADAMANY, ANTHONY M
ADAMS, D F
ADAMS, D F
ADAMS, DOUGLASS F
ADAMS, G KENNETH
ADAMS, WILLIAM H
ADDONIZIO, V PAUL
ADKINSON, N FRANKLI
AHRENS, EDWARD H, J
AHRENS, EDWARD H, J
AHRENS, EDWARD H, J
AIELLO, EDWARD L
AINSWORTH, STERLING
AISENBERG, SOL
AKERA, TAI
AKUTSU, TETSUZO
ALAWQATI, QAIS
ALADJEM, FREDERICK
ALAUPOVIC, PETAR
ALBERS, JOHN J
ALBERT, ERNEST N
ALBRIGHT, JOHN T
ALDERMAN, EDWIN L
ALDERMAN, EDWIN L
ALDERMAN, EDWIN L
ALDERMAN, MICHAEL H
ALEDORT, LOUIS M
ALEXANDER, A V
ALEXANDER, EDWARD A
ALEXANDER, EDWARD A
ALEXANDER, NATALIE
ALEXANDER, DATES J
ALFREY, CLARENCE P,
ALLCOCK, HARRY R
ALLEN, FRED H
ALLEN, GARY C
ALLEN, SINCLAIR T,
ALLEN, SINCLAIR T,
ALLEN, SINCLAIR T,
ALLEN, SINCLAIR T,
ALMQUIST, RONALD G
ALONSO, DANIEL R
ALONSO, DANIEL R
ALONSO, DANIEL R
ALONSO, DANIEL R
ALPERT, NORMAN R
ALPERT, NORMAN R
ALS, ANN V
ALTURA, BURTON M
ALTURA, BURTON M
AMES, A DELBERT
P01HL1438807
P01HL1438807 0151
P01HL14388-07 0152
P01HLU38807 0153
P01HL1438807 0154
P01HLU38807 0155
P01HL1438807 0156
P01HL1438807 0157
P01HL1438807 0158
P01HLU38807 0159
P01HL1438807 0160
P01HL14388 07 0161
P01HL1438807 0162
P01HL1438807 0163
P01HL14388-07 0164
P01HL14388-07 0165
P01HL1438807 0166
P01HL14388-07 0167
P01HL1438807 0185
P01HL1438807 0195
P01HL14388-07 0209
P01HL1438807 0229
POIHL 14388-07 9005
N01HV2291309
R01HL1881403
P01HL1053912
P01HL1053912 0068
P01HL10539-12 0069
R01HL19267-02
P01HL13480-09
POIHL 1348009 0017
P50HL1414708 0014
R23HL19619-01
R0IHL2089503
R01HL20895-03 0007
R01HL20895-03 0011
R01HL22718-01
P50HL1421207 0016
R01HL16791-03
R01HL1864703
POIHLI 131012 0097
R01HL19011-03
R01HL20895-03 0003
R01HL20895-03 0005
R01HL21719-01
P50HL1415307 0013
P60HL15157-07 0001
R23HL2234601
P50HL14153-07 0012
R01HL06222-18
P50HL14236-05
P50HL14236-05 0009
R01HL16730-03
R01HL16490-04
N01HV32919-12
R01HL16052-05
R01HL18084-03
R01HL21849-02
R01HL19084-03
R01HL0622117
R01HL15263-06
R01HL12557-09
P01HL19717-02 0022
R01HL17993-04 0003
R01HL17993-04 0005
N01HV32974-09
P50HL18323-04 0035
N01HB53020-04
R01HL18191-04
R01HL17458-04
P50HL18318-03 0007
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AMINOFF, DAVID
AMMA, ELMER L
AMMANN, ARTHUR I
AMPWTZ,
AMPLATZ, KURT
AMPLATZ, KURT
ANAGNOSIOPOUIOS, C
ANDERSON, BANKS, JR
ANDERSON, DAVID E
ANDERSON, GUNNAR H,
ANDERSON, JAMES M
ANDERSON, JAMES M
ANDERSON, LEWIS D
ANDERSON, NORMAN D
ANDERSON, PAGE A
ANDERSON. RICHARD G
ANDERSON, ROBERT W
ANDRAOE, JOSEPH D
ANDRADE, JOSEPH D
ANGELAKOS, EVANGELO
ANTHONISEN, NICHOLA
ANTHONISEN, NICHOLA
APFEL, ROBERT E
APOSTOLIDES, ARISTI
APOSTOLIOES, ARISTI
ARCHER, GORDON L
ARCHIE, JOSEPH P
ARGELES, H J
ARMSTRONG, MARK L
ARMSTRONG, MARK L
ARNSOORF, MORTON F
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ARONSON, J F
ARONSON, RONALD S
ARTHUR, R MARTIN
ASAKURA, TOSHIO
ASAKURA, TOSHIO
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ASKARI, AMIR
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ASTER, RICHARD H
ATABEK, BULENT H
ATKINS, FLOYD L
ATKINS, HAROLD L
ATKINS, JAMES M
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AZAR, SILVIA
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BACHE, ROBERT J
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BAER, PAUL E
BAERWALD, ROY J
BAEZ, SILVIO
BAEZ, SILVIO
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BAGBY, SUSAN P
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BAGDADE, JOHN D
BAGLIONI, CORRADO
BAHLER, AWN S
BAIER, ROBERT E
BAILEY, J MARTYN
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BAILEY, JOHN C
BAILEY, JOHN M
BAKER, CARLETON H
BAKER, DONALD W
BAKER, DONALD W
BAKER, DONALD W
BAKER, DONALD W
BAKER, JOHN
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BAKER, RICHARD
BALCERZAK, STANLEY
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BALDWIN, JACK E
BALDWIN, JACK E
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BALFOUR, H H, JR
BALINT, JOHN A
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BALLARD, PHILIP L
BANCHERO, NATALIO
S85
R01HL1788I 15
P60HL1515807 0014
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N01HR7290204
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P01HL06314-17 0061
R01HL15273-06
R23HL21253-01
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R01HL18145-03
ALPHABETICAL LISTING OF INVESTIGATORS
BANERJEE, SHAILESH
BANG, FREDERIK B
BANK, NORMAN
BANK, NORMAN
BARAJAS, LUCIANO
BARANOWSKI, TOM
BARBEE, ROBERT
BARBER. FRANK F
BARBERO, GIULIO J
BARBORIAK, JOSEPH J
BARBORIAK, JOSEPH J
BARENHOLZ, YECHEZKE
BARGER, A CLIFFORD
BARGER, A CLIFFORD
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BARNDT, ROBERT, JR
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BARNER, HENDRICK B
BARNER, HENDRICK B
BARNER, HENDRICK B
BARNER, HENDRICK B
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BARR, LLOYD
BARREn, JACK D
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BASHE, WINSLOW J, J
BASOLO, FRED
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BASSINGTHWAIGHTE, J
BAUE, ARTHUR E
BAUER, CHARLES
BAUMANN, WOLFGANG J
BAUMANN, WOLFGANG J
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BAUR, PAUL S
BAXLEY, WILLIAM A
BAXLEY, WILLIAM A
BAXTER, JOHN D
BAYLIN, STEPHEN B
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BECK, NAMA
BECKER, CARL G
BECKER, CARL G
BECKER, CARL G
BECKER, CARL G
BECKER, CARL G
BECKER, CARL G
BECKER, CARL G
BECKER, CARL G
BECKER, LEWIS
BECKER, LEWIS C
BECKER, LEWIS C
BELL, D G
BELL, ROBERT G
BELLANTI, JOSEPH A
BELLANTI, JOSEPH A
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BENESCH, RUTH E
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BENNEn, PETER B
BENNETT, PETER B
BENSADOUN, ANDRE
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BENSON, ELLIS S
BENSON, ELLIS S
BENSON, ELLIS S
BENSON, ELLIS S
BENSON, HERBERT
BENSON, HERBERT
BENSON, HERBERT
BENSON, HERBERT
BENSUSAN, HOWARD E
BERENSON, GERALD S
BERENSON, GERALD S
BERENSON, GERALD S
BERGE, KENNETH B
BERGOFSKY, EDWARD
R01HLI8I8504
P50HLI9157 02 0004
R01HL1472OO8
R01HL1936603
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N01HV7292700
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R01HL2285201
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R01HL05791-18
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POIHLI 1678-11 0057
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R01HL18186-04
P01HL07896-15
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R01HL14990-07
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P01HL16833-04 0004
P01HL10539-12 0023
P01HL10539-12 0031
P01HL10539-12 0065
P01HL10539-12 0066
I R01HL22081-20
R01HL02942-22
P50HL15103-07
P50HL15103-07 0001
R01HL08892-10
H R01HL17711-05
ALPHABETICAL LISTING OF INVESTIGATORS
BERGOFSKY, EDWARD H
BERGUER, RAMON
BERKOFF, HERBERT A
BERMAN, REUBEN
BERMAN, WILLIAM, JR
BERNE, ROBERT M
BERNE, ROBERT M
BERNHARD, WILLIAM F
BERNS, MICHAEL W
BERNSTEIN, EUGENE F
BERNSTEIN, EUGENE F
BERNSTEIN, EUGENE F
BERNSTEIN, EUGENE F
BERRY, GUY C
BERTLES, JOHN F
BESCH, HENRY R, JR
BETTICE, JOHN A
BEUTLER, ERNEST
BEVAN, JOHN A
BEVAN, JOHN A
BEVAN, JOHN A
BEVAN, JOHN A
BEVAN, ROSEMARY D
BEVAN, ROSEMARY D
BEVAN, ROSEMARY D
BHALLA, RAMESH C
BHAM, ASHOK K
BHATNAGAR, RAJENDRA
6HATNAGAR, RANBIR K
BHAHACHARYYA, ASHI
BIANCHI, C PAUL
BIEBER, CHARLES P
BIEBER, CHARLES P
BIEBER, CHARLES P
BIEBER, CHARLES P
BIEBER, CHARLES P
BIEBER, CHARLES P
BIENKOWSKI, ROBERT
BIERMAN, EDWIN L
BIGGER, J THOMAS, J
BIGLER, RODNEY E
BILEZIKIAN, JOHN P
BILHEIMER, DAVID W
6ILLINGHAM, MARGARE
BING, OSCAR H
BING, OSCAR H L
BING, OSCAR H L
BIRNBAUMER, LUTZ
BISHOP, BEVERLY
BISHOP, DAVID H L
BISHOP, SANFORD P
BISHOP, VERNON S
BISNO, ALAN L
BinAR, NEVILLE
BITTMAN, ROBERT
BinWAN, ROBERT
BJORNSON, ANN B
BLACKBURN, HENRY W
BWCKSHEAR, PERRY L
BLACKSHEAR, PERRY L
BLACKSTONE, EUGENE
BLACKSTONE, EUGENE
BLACKSTONE, EUGENE
BLACKSTONE, EUGENE
BLACKSTONE, EUGENE
BLACKSTONE, EUGENE
BLACKWELL, JOHN
BLAINE, EDWARD H
BUIR, MARTHA L
BLANC, WILLIAM A
BLAND, RICHARD D
BLAND, RICHARD D
BLANKENHORN, DAVID
BIANKENHORN, DAVID
BLANTZ, ROLAND C
BLASIE, J KENT
BLAUFOX, MORTON D
BLEECKER, EUGENE R
BLINKS, JOHN R
BLOCH, KONRAD E
BLOCK, A JAY
BLOCK, EDWARD R
BLOMBACK, BIRGER E
BLOMBACK, G BIRGER
BLOMQVIST, C GUNNAR
BLOMQVIST, GUNNAR
BLOOM, SHERMAN
BLOOVQUIST, EUNICE
BLOOR, COLIN M
BLOOR, COLIN M
BLOOR, COLIN M
BLOOR, COLIN M
R01HL23210-01
R01HL19406-03
R01HL19378-03
N01HV22937-07
R01HL23980-01
R01HL10384-13
P01HL19242-02
R01HL20037-02
R01HL15740-06
P01HL18576-03 0001
P01HL18576-03 0010
R01HL18948-03
R01HL22741-01
N01HV32949-11
P01HL16851-04 0005
P01HL06308-18 0025
R23HL19601-01
R01HL07449-17
R01HL08359-14
R01HL15805-06
P01HL20581-01
P01HL20581-01 0001
P01HL20581-01 0002
P01HL20581-01 0005
P01HL20581-01 9001
R01HL19027-03
R01HL23994-01
ROIHL 19668-03
P01HL14388-07 0193
P01HL08974-14 9001
P01HL15835-06 0018
P01HL13108-09 0002
P01HL13108-09 0010
P01HL13108-09 0011
P01HL13108-09 0012
P01HL13108-09 0013
P01HL13108-09 0015
R01HL22729-01
N01HV12157-14
P01HL12738-10 0117
R01HL22371-01
R01HL20859-02
R01HL15949-05
P01HL13108-09 0003
R01HL18338-04
P01HL10539-12 0067
P01HL20552-02 0003
R01HL19423-03
P01HL14414-07 0007
P01HL11310-12 0100
P50HL17667-04 0045
R01HL12415-10
P60HL15169-05 0009
R01HL17759-03
R01HL16660-06
R01HL22052-01
R01HL20314-02
N01HV22976-07
P01HL16833-G4 0008
R01HL21 188-02
POIHLI 1310-12 0054
P01HL11310-12 0060
P01HL11310-12 0061
POIHLI 1310-12 0068
P01HL11310-12 0069
P50HL1 7667-04 0022
R01HL21622-02
R01HL22617-01
R23HL22728-01
P01HL17813-04 0002
P50HL19185-02 0004
P50HL19185-02 0007
P50HL14138-05
N01HV72930-02
R01HL14914-06
P01HL18708-03 0004
N01HV22931-14
P01HL10342-13 0028
R01HL12186-09
R01HL02477-23
R01HL22622-01
R01HL21115-01
R01HL07379-13
P01HL09011-15 0002
P50HL17669-04 0013
P01HL06296-18 0003
R01HL22137-02
R01HL19012-03
P01HL12373-10 0016
P50HL1 7682-04 0012
P50HL1 7682-04 0016
R01HL20190-02
BLUMENFELD, OLGA
BLUMENSTOCK, DAVID
BLUMENTHAL,
MALCOLM
BOAT, THOMAS F
BOAT, THOMAS F
BOAT, THOMAS F
BOCKMAN, EMMA L
BOERTH, ROBERT C
BOGGS, DANE R
BOHLEN, HAROLD G
BOHR, DAVID F
BOHR, DAVID F
BOHR, DAVID F
BOHR, DAVID F
BOINEAU, JOHN P
BONAVENTURA, JOSEPH
BONCHEK, LAWRENCE I
BOND, GARY C
BOND, M GENE
BONILLA, CARLOS A
BOOKCHIN, ROBERT M
BOOKCHIN, ROBERT M
BOOKCHIN. ROBERT M
BOOKSTEIN, JOSEPH J
BOOR, PAUL J
BOOYSE, FRANCOIS M
BORDERS, STEPHEN E
BOREJDO, JULIAN
BORHANI, NEMAT 0
BORHANI, NEMAT 0
BORHANI, NEMAT 0
BORNSTEIN, PAUL
BOROS, DOV L
BOROS, DOV L
BOROWITZ, IRVING J
BORTIN, MORTIMER M
BOSIN, TALMAGE R
BOSSEN, EDWARD H
BOTTS, JEAN
BOUCEK, ROBERT J, J
BOUCEK, ROBERT J, J
BOUCEK, ROBERT J, J
BOUCEK, ROBERT J, J
BOUCHER, RICHARD C
BOUHUYS, AREND
BOURASIA, MARTIAL B
BOURLAND, JOE D
BOURUND, JOE D
BOVE, ALFRED A
BOWIE. E J
BOWIE, E J WALTER
BOWMAN, BARBARA H
BOWMAN. JAMES E
BOWMAN, JAMES E
BOYARSKY, LOUIS L
BOYLEN, C THOMAS
BRACE, ROBERT A
BRACE, ROBERT A
BRADFORD, REAGAN H
BRADLEY. RONALD J
BRADLEY, THOMAS B
BRADY, ALLAN J
BRADY, ALWN J
BRADY, ALLAN J
BRADY, ALLAN J
BRADY, JUNE P
BRAIN, JOSEPH D
BRAIN, JOSEPH D
BRAIN, JOSEPH D
BRAIN, JOSEPH D
BRANCH, GERALDINE
BRANDTS, JOHN F
BRANTON, DANIEL
BRATER, DONALD C
BRATZLER, ROBERT L
BRAUMAN, SHARON K
BRAUN, NORMA
BRAUNWALD, EUGENE
BRAUNWALD, EUGENE
BRAUNWALD, EUGENE
BRAUNWALD, EUGENE
BRAUNWALD, EUGENE B
BRAVERMAN, BERTON
BRAVERMAN, BERTON
BRAVO, EMMANUEL L
BRAVO, EMMANUEL L
BRAVO, EMMANUEL L
BRAVO, EMMANUEL L
BRAVO, EMMANUEL L
BRAVO, EMMANUEL L
BRAVO, EMMANUEL L
586
P50HL14236-05 0008
R01HL13987-04
R01HL23631-01
R01HL13885-08 0009
R01HL14844-06
N01HR52957-02
R01HL17932-04
R01HL17629-03
R01HL19333-03
R01HL20605-02
P01HL18575-03
P01HL18575-03 0001
P01HL18575-03 0009
P01HL18575-03 0010
R01HL18398-04
R01HL15460-06
R01HL21071-02
R01HL21094-01
P50HL14164-07 0031
R01HL16233-05
P01HL21016-02 0003
P01HL2 1016-02 0006
P01HL21016-02 0007
R01HL19675-02
R23HL21327-02
R01HL17973-04
R23HL22745-01
P01HL16683-04 0001
N01HV22945-11
N01HV22977-08
N01HV72954-06
P01HL18645-03 0003
R01HL19732-03
R01HL20104-03
R01HL16746-04
N01HB62963-03
R23HL19573-01
R01HL15888-05
P01HL06285-18 0173
R01HL17865-04
R01HL17909-04
R23HL21234-02
R01HL22040-01
R01HL22924-01
R01HL21352-02
N01HV32983-11
R01HL20629-02
R01HL22321-01
R01HL19425-03
P01HL17430-05
P01HL17430-05 0001
N01HR72922-01
P60HL16005-05
P60HL16005-05 9001
P01HL16878-05 0004
N01HR62947-04
POIHLI 1678-11 0035
POIHLI 1678-11 0070
N01HV22932-09
POIHLI 1310-12 0102
P60HL20985-01 0003
P01HL11351-12
P01HL1135M2 0003
POIHLI 1351-12 0005
P01HL11351-12 0019
P50HL19185-02 0009
R01HL17543-03 0004
P50HL19170-02
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P50HL191 70-02 0004
P60HL23282-01 9002
R01HL17878-04
R01HL17411-04
R23HL22882-01
R01HL18736-03
N01HV32959-10
P01HL17813-04 0006
P01HL20552-02
P01HL20552-02 0001
P01HL20552-02 0002
R01HL23140-01
N01HV72940-02
P01HL08682-15 0026
P01HL08682-15 0027
P01HL06835-17 0045
P01HL06835-17 0046
P01HL06835-17 0047
P01HL06835-17 0048
P01HL06835-17 0049
P01HL06835-17 0050
P01HL06835-17 0051
BRAVO. EMMANUEL L
BRAVO. EMMANUEL L
BRAVO, EMMANUEL L
BRAVO, EMMANUEL L
BRAVO, EMMANUEL L
BRAVO, EMMANUEL L
BRECHER, PETER I
BREGMAN, DAVID
BREGMAN, DAVID
BRENEMAN, GERALD M
BRENNAN, ROBERT W
BRESLOW, JAN L
6RESSLER, RUBIN
BREWER, GEORGE J
BREWER, GEORGE J
BRIEHL. ROBIN W
BRIERLEY. GERALD P
BRIERLEY, GERALD P
BRIGGS, F NORMAN
BRIGHAM, KENNETH L
BRIGHAM, KENNETH L
BRIGHAM, KENNETH L
BRIGHAM, KENNETH L
BRIGHAM, KENNETH L
BRILL, A B
BRILL, ARTHUR S
BRINKHOUS, KENNETH
BRINKHOUS, KENNETH
BRINKLEY, JAMES
BRINKMAN, CHARLES R
BRISCOE, WILLIAM A
BROCKMAN, HOWARD L
BROCKMAN, HOWARD L,
BROCKMAN, HOWARD L,
BRODHEIM, ERIC
BRODY, JEROME S
BRODY, JEROME S
BRODY, JEROME S
BRODY, JEROME S
BRODY, JEROME S
BRODY, JEROME S
BRODY, MICHAEL J
BRODY, MICHAEL J
BRODY, MICHAEL J
BRODY, MICHAEL J
BRODY, MICHAEL J
BRODY, MICHAEL J
BRODY, MICHAEL J
BRODY, MICHAEL J
BRODY, MICHAEL J
BRODY, MICHAEL J
BRODY, MICHAEL J
BROMBERGER-BARNEA,
BROOKER, GARY
BROOKER, GARY
BROOKS, HAROLD L
BROOKS, HAROLD L
BROOKS, SAMUEL H
BROOKS, STUART M
BROWN, ARTHUR C
BROWN, ARTHUR M
BROWN, ARTHUR M
BROWN, ARTHUR M
BROWN, AUDREY K
BROWN, AUDREY K
BROWN, AUDREY K
BROWN, 8 GREG
BROWN, DAVID M
BROWN, MICHAEL S
BROWN, MICHAEL S
BROWN, MICHAEL S
BROWN, MICHAEL S
BROWN, OLIVER M
BROWN, W VIRGIL
BROWNELL, KELLY D
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BUCCI, CLARA F
BUCCI, ENRICO
BUCHANAN, DENTON C
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BUCHWALD, HENRY
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BUCHWALD, HENRY
BUCHWALD, HENRY
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587
ALPHABETICAL LISTING OF INVESTIGATORS
BUCHWALD. HENRY
BUCHWALD. HENRY
BUCHWALD. HENRY
BUCHWALD, HENRY
BUCHWALD, HENRY
BUCHWALD. HENRY
BUCHWALD. HENRY
BUCHWALD, HENRY
BUCHWALD, HENRY
BUCHWALD. HENRY
BUCK. KEITH S
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BUCKBERG, GERALD D
BUCKBERG. GERALD D
BUCKBERG. GERALD D
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BUDINGER. THOMAS F
BUDZYNSKI, ANDREI 2
BUJA, L MAXIMILIAN
BULKLEY, BERNADINE
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BUMPUS, F MERLIN
BUMPUS, F MERLIN
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BUMPUS, F MERLIN
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BUMPUS, F MERLIN
BUMPUS, F MERLIN
BUMPUS, F MERLIN
BUMPUS, F MERLIN
BUMPUS, F MERLIN
BUMPUS, F MERLIN
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BUNAG, RUBEN D
BUNAG, RUBEN D
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BUONASSISI. VINCENZ
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BURGESS, MARY J
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BURKI, N K
BURNS, BARRY
BURNS, BARRY
BURNS, CHARLES P
BUROW. ROBERT D
BURROWS. BENJAMIN
BURROWS, BENJAMIN
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BURST, SANIA
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BURTON, JAMES A
BUSCH, GEORGE J
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BUTLER, COOLEY, II
BUTLER, JOHN
BUTLER, JOHN
BUTLER, VINCENT P
BUTLER, VINCENT P,
CADENHEAD, DAVID A
CADY, LEE D
CAHILL, PATRICK T
CAIN, STEPHEN M
CALA, PETER M
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CALDWELL, ROBERT W
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P01HL1526505
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ROIHLI 7995-04
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CAMPBELL. GILBERT S
CAMPBELL. KENNETH B
CAMPBELL. WALWCE G
CAMPBELL. WILLIAM B
CANESSA. MITZY
CANFIELD. ROBERT E
CANN. JOHN R
CANNER, PAUL
CANNON. PAUL J
CANNON. PAUL J
CANNON, PAUL J
CANNON. PAUL J
CANNON, PAUL J
CANNON, PAUL S
CANOSA, FRANK L
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CAPLAN, ROBERT D
CAPONE, ROBERT J
CAREY, KENNETH D
CAREY, ROBERT M
CARIDE, VICENTE J
CARLSON, JAMES R
CARNES, WILLIAM H
CARRETERO, OSCAR A
CARRETERO, OSCAR A
CASE, DAVID B
CASE, DAVID B
CASE, ROBERT B
CASKEY, CHARLES T
CASSELL, GAIL H
CASSIN, SIDNEY
CASTELLINO, FRANCIS
CASTELLINO, FRANCIS
CASTLE, CHARLES H
CASTLE, MANFORD C
CASTOR, C WILLIAM
CASTRANOVA, V
CASTRANOVA, V
CASTRO, OSWALDO
CASTRO, OSWALDO
CASTRO, OSWALDO
CASWELL, ANTHONY P
CATANZARO, P
CATTERALL, WILLIAM
CAUGHEY, WINSLOW S
CENTER, DAVID
CERAMI, ANTHONY
CERAMI, ANTHONY
CEVALLOS, WILLIAM H
CHACKO, SAMUEL
CHACKO, SAMUEL K
CHADWICK, JOSEPH H
CHAN, LEE-NIEN L
CHAN, LEE-NIEN L
CHAN, SHUNG K
CHANCE, BRITTON
CHANCE, BRinON
CHANCE, BRinON
CHANCE, BRinON
CHANCE, BRITTON
CHANDRAN, KRISHNAN
CHANG, HSIN-KANG
CHANG, TA-YUAN
CHAO, FRANCIS C
CHAO, TESSA L
CHAPMAN, KENT M
CHAPNICK, BARRY M
CHAPPLE, PAUL J
CHARACHE, SAMUEL
CHASE, CHRISTOPHER
CHEN, EDWIN H
CHEN, JAMES P
CHENEY, FREDERICK W
CHENG, PI-WAN
CHERNIACK, NEIL S
CHERNIACK, R M
CHESEBRO, JAMES H
CHESLER, DAVID A
CHESNEY, CAROLYN M
CHEUNG, PETER W
CHEUNG, PETER W
CHEVALIER, PETER A
CHI, EMIL Y
CHIEN, SHU
CHIEN, SHU
CHIEN, SHU
CHIEN. SHU
CHIEN, SHU
CHIEN, SHU
CHIEN, SHU
CHILCOTE, ROBERT R
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R23HL2146202
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POIHL 1548606 0001
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R01HL14148-07
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P50HL14236-05 0002
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CHILDERS, RORY W
CHIMOSKEY. JOHN E
CHIN, H P
CHINARD. FRANCIS P
CHINARO. FRANCIS P
CHINARD, FRANCIS P
CHINARD, FRANCIS P
CHINARD, FRANCIS P
CHINARD, FRANCIS P
CHIPAULT, J R
CHITWOOD. W RANDOLP
CHOBANIAN, ARAM V
CHOBANIAN, ARAM V
CHOBANIAN. ARAM V
CHOBANIAN, ARAM V
CHOBANIAN, ARAM V
CHOU, CHING-CHUNG
CHRISTAKIS, GEORGE
CHRISTIAN, EMILY
CHUANG, HANSON Y
CHVAPIL, MILOS
CHYTIL, FRANK
CHYTIL, FRANK
CIFONELLI, J ANTHON
CLARK, JAMES M
CLARK, JAMES M
CLARK, JAMES M
CLARK, JAMES M
CLARK, JAMES M
CLARK, JAMES M
CLARK, JAMES M
CLARK, JEFFREY N
CLARK, JUSTIN S
CLARK, LELAND C, JR
CLARK, MARGARET R
CLARK, RICHARD E
CLARKE. STEVEN D
ClARKSON, THOMAS B
CLARKSON, THOMAS B
CLARKSON, THOMAS B
CLARKSON, THOMAS B
CLARKSON, THOMAS B
CLARKSON, THOMAS B
CLARKSON, THOMAS B
CLAYTON, PAUL D
CLAYTON, PAUL D
CLAYTON, PAUL D
CLEMENTS, JOHN A
CLEMENTS, JOHN A
CLEVEUND, WILLIAM
CLYDE, WALLACE A, J
CLYDE, WALLACE A, J
CLYMAN, RONALD I
COBB, FREDERICK R
COBB, FREDERICK R
COBB. LEONARD A
COBURN, RONALD F
COBURN, RONALD F
COCHRANE, CHARLES G
COELHO, ANTHONY M
COFFMAN, JAY D
COFFMAN, JAY D
COGHAN, H CECIL
COHEN, ALLAN B
COHEN, ALLAN B
COHEN. BERNICE H
COHEN, CHARLES J
COHEN, DAVID
COHEN. DAVID
COHEN, DAVID
COHEN, HOWARD C
COHEN, IRA S
COHEN, ISAAC
COHEN, JOEL A
COHEN, JORDAN J
COHEN, JORDAN J
COHEN, JULES
COHEN, LOUIS
COHEN, MICHAEL V
COHEN, MORTON I
COHEN, WILLIAM 0
COHN, JAY N
COHN, JAY N
COHN, LAWRENCE H
COLACICCO, GIUSEPPE
COLE, EDMOND R
COLE, JAMES S
COLEMAN, THOMAS G
COLEMAN, THOMAS G
COLEMAN, THOMAS G
COLERIDGE, JOHN C G
COLGAN, FRANK J
P50HL17648 04 0018
PO1HL1333O08 0059
P50HL1413805 0008
R01HL1287909
R01HL12879 09 0005
R01HL1287909 0006
R01HL1287909 0007
R01HL1287909 0008
R01HL12974 10
P01HL08214-15 0010
P01HL07896-15 0059
ROIHLI 2869-09
P50HL18318 03
P50HL1831803 0001
P50HL18318-03 0011
P50HL18318-03 0014
R01HL15231-05
N01HV42933-09
P60HL1 599606 0005
R01HL22585-01
R01HL1963302
P50HL1421407 0023
R01HL15341-06
R01HL1982002
P01HL0889914 0035
P01HL0889914 0036
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P01HL08899-14 0055
P01HL08899-14 0056
P01HL08899-14 0057
R01HL22259-01
R23HL2 1369-02
R01HL20351-02
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R01HL23159-01
P50HL14164-07
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P50HL14164-07 0032
P50HL14164-07 0041
N01HV53029-04
N01HV7297802
P01HL04664-18 0014
P01HL04664-18 0015
R01HL21785-01
P01HL06285-18 0208
P50HL19185-02
P50HL14141-05 0007
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R23HL21409-02
P50HL1 7670-04 0020
R01HL18537-04
R01HL18805-04 0004
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P01HL11678-11 0058
POIHLI 1678-11 0068
P01HL11678-11 9001
P01HL06285-18 0180
R01HL09609-11
ALPHABETICAL LISTING OF INVESTIGATORS
COLLER, BARRY S
R01HL19278-03
COLLIER, ALBERT M
P50HL19171-02 0001
COLLIER, ALBERT M
P50HL1917102 0008
COLLINS, FRANK M
R01HL19774-03
COLLINS, JOHN
P01HL22619-01 0002
COLMAN, ROBERT W
R01HL1664205
COLMAN, ROBERT W
P01HL18827-02
COLMAN, ROBERT W
P01HL1882702 0005
COLMAN, ROBERT W
P01HL18827-02 0007
COLTON, CLARK K
R01HL21429-02
COLWELL, WILLIAM T
R01HL19066-03
COMSTOCK, GEORGE W
R01HL1907302
CONDORELLI, SALVATO
P01HL16137-05 0013
CONGER, JOHN D
R01HL18097-04
CONNOR, WILLIAM E
R01HL209I0-02
CONRAD, H EDWARD
R01HL21763-09
CONRAD, MARCEL E
P01HL11310-12 0095
CONRAD. MARCEL E
R01HL20856-02
CONRAD, MARGARET C
R01HL21034-01
COOK, JAMES M
R01HL1789703
COOPER, ALLEN D
R01HL0536019
COOPER, DAVID Y
P01HL08899-14 0062
COOPER, GEORGE, IV
R01HL2157001
COOPER, STUART L
R01HL2100101
CORDAY, ELIOT
R01HL14644-05
CORDAY, ELIOT
P50HL17651-04 0016
CORLEY, KARL C, JR
R01HL13454-08
CORNFIELD, JEROME
P50HL14236-05 0010
CORNFIELD. JEROME
R01HL1519107
CORNWELL, DAVID G
R01HL11897-11
CORR, PETER B
R01HL21654-01
CORRIGAN. JAMES J.
R01HL2143102
CORSON. SAMUEL A
R01HL2086101
CORTNER, JEAN A
R01HL18723-03
CORYA, BEnY C
P01HL06308I8 0042
, COSIMI, A BENEDICT
li COSIMI. A BENEDICT
P01HL1864603 0001
P01HL1864603 0002
COSIMI, A BENEDICT
P01HLI864603 0003
COSTILL, DAVID L
R01HL2040803
COSTLOW, JOHN D
P01HL07896-15 0060
COTRAN, RAMZI
P01HL20552-02 9001
COTRAN, RAMZI S
P01HL06370-17
COTRAN, RAMZI S
P01HL22602-01
COTRAN, RAMZI S
P01HL2260201 0003
COnON, ERNEST K
R01HL15430-05
COnON, ROBERT B
P50HL14214-07 0030
COnON, ROBERT B
P50HL1421407 0033
COnON, ROBERT 8
P50HL14214-07 0036
COULSON, LORNE R
R01HL19461-03
COUNTS, RICHARD B
P60HL1 7265-04 0002
COURTNEY, KENNETH R
R01HL2174201
COVELL, JAMES W
P01HL12373-10 0001
COVELL, JAMES W
P01HL1237310 0014
COVELL, JAMES W
P01HL12373-10 0015
COVELL, JAMES W
P50HL1 7682-04 0009
COVELL, JAMES W
P50HL1 7682-04 0013
COWLEY, ALLEN W. JR
P01HL11678-11 0027
COWLEY, ALLEN W, JR
POIHLI 1678-11 0069
f COWLEY, ALLEN W, JR
P01HL11678-11 9002
COWLEY, ALLEN W, JR
R01HL14306-07
COX, EMMA
P60HL1 5996-06 0006
COX, ROBERT H
R01HL19256-03
CRAIGHEAD. JOHN E
P60HL1 7292-04 0005
CRAIGHEAD, JOHN E
P50HL14212-07 0011
CRAIGHEAD, JOHN E
1 CRAIGHEAD, JOHN E
1: CRAIGHEAD, JOHN E
P50HL14212-07 0012
P60HL1 7292-04
P60HL1 7292-04 0003
i CRANDALL, EDWARD D
P01HL1973702 0005
||. CRANDALL, EDWARD D
P01HL1973702 0010
Hi CRANEFIELD, PAUL F
R01HL14899-07
■ CRAPO, J D
P01HL07896-15 0039
11 CRAVALHO, ERNEST G
R01HL20219-02
lil CRAVEN, BRYAN M
R01HL20350-02
» CRAWFORD, DONALD W
P50HL14 138-05 0009
m CRAWFORD, DONALD W
R01HL18969-02
'■ ' CRAWFORD, DONALD W
R01HL21032-02
CREASY, ROBERT K
P01HL06285-18 0133
CREASY, ROBERT K
P0IHLO6285-18 0134
CREASY, ROBERT K
P01HL06285-18 0135
CREER, THOMAS
N01HR72972-01
CRIQUI, MICHAEL H
R01HL22255-01
CRITCHLOW, CATHY
P60HL17265-04 0001
CRONKITE, EUGENE P
R01HL15685-05
CROW, RICHARD S
R01HL21307-01
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DEYKIN, DANIEL
OHARMARAJAN. VENKAT
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Dl BONA, GERALD F
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DISALVO, JOSEPH
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DOBRIN. PHILIP B
DOBSON. JAMES G. JR
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ECKBERG. OWAIN L
ECKSTEIN, EUGENE C
EDOLEMAN, E E
EDELMAN. ISIDORE S
EDELMAN, ISIDORE S
EDELMAN, ISIDORE S
EDELMAN, ISIDORE S
EDELMAN, ISIDORE S
EDELMAN, NORMAN H
EDER, HOWARD A
EOER. HOWARD A
EDER, HOWARD A
EDGINGTON, THOMAS S
EDMONDS, S RANDOLPH
EDMUNDS. L HENRY. J
EDWARDS. JESSE E
EDWARDS. PETER A
EFFROS. RICHARD M
EGAN, EDMUND A
EGGEN, DOUGLAS A
EHRHART, ALLEN
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EHRIE, MICHAEL
EHRIE. MICHAEL
EHRLICH. KENNETH C
EINZIG, STANLEY
EISENBERG, ROBERT S
EISENSTAOT, MAURICE
EISENSTEIN, REUBEN
EISENTHAL, KENNETH
ELBERMANI. AL-WALI
ELBAUM. DANEK
ELBAUM, DANEK
ELBEIN, ALAN D
ELDER, S THOMAS
ELORIDGE. FREDERIC
ELLIOT. DAVID L
ELLIOn, WILLIAM H
ELLISON. ROBERT C
ELZINGA, MARSHALL
EMANUEL. DEAN A
EMANUEL. DEAN A
EMESON. EUGENE
ENGELMAN. DONALD M
ENGLANDER. S WALTER
ENGLE. MARY A
ENNS. THEODORE
ENSON. YALE
ENTMAN. MARK L
ENTMAN, MARK L
ENTMAN, MARK L
ENTMAN. MARK L
EROOS. ERVIN G
ERDOS. ERVIN G
ERDOS, ERVIN G
ERECINSKA, MARIA
ERFURT. JOHN C
ERICKSON, BRUCE W
ERICKSON, JAMES R
ERIKSEN. NILS
ERSLEV, ALLAN J
ERTEL, ROBERT J
ESCHER, DORIS J
ESKIN. S G
ESTENSEN, RICHARD D
ETLINGER. JOSEPH D
EHINGER, PHILIP 0
EVANS. EVAN A
EVANS. JOHN N
EVANS, JOHN W
EVANS, JOHN W
EVANS, MICHAEL J
EVANS. RICHARD I
EVANS, TITUS C
EYSTER, M ELAINE
FABIATO. ALEXANDRE
FABRICANT, GATHER IN
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FAIRCLOUGH. GORDON
FALK, CATHERINE T
FALL, R RAY
FALLAT, ROBERT J
FALSEHI, HERMAN L
FALSETTI, HERMAN L
FANBURG, BARRY L
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FANBURG, BARRY L
FARA, JOHN W
FARBER, JAY P
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FARMER. JOSEPH C, )
FARMER, JOSEPH C, J
FAROUHAR. JOHN W
FASCO, MICHAEL J
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FAY, FREDRIC S
FEENEY, ROBERT E
FEIGENBAUM, HARVEY
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FEINSTEIN, MAURICE
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FELOMAN, ELAINE B
FELDMAN, HENRY A
FELDMAN, STUART
FELTS, JAMES M
FENTON, JOHN W. II
FERNALD. GERALD W
FERNALD. GERALD W
FERNALO. GERALD W
FERNANDEZ. SALVADOR
FERRARIO. CARLOS M
FERRARIO, CARLOS M
FERRIERI, PATRICIA
FERRIS, THOMAS F
FERTEL, RICHARD H
FIALA, MILAN
FIELDING, CHRISTOPH
FIELDING, CHRISTOPH
FILKINS, JAMES P
FILKINS, JAMES P
FILKINS, JAMES P
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FINCH, CLEMENT A
FINK, B RAYMOND
FINK, JORDAN N
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FINLAY, THOMAS H
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FISH, ALFRED J
FISH, WAYNE W
FISHBEIN, MICHAEL C
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FISHER, ARON B
FISHER, EDWIN B, JR
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FLETCHER, DOROTHY
FLORENTIN, RODOLFO
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FLOWERS, NANCY C
FOGELMAN, ALAN M
FOGELMAN, ALAN M
FOLKERS, KARL
FOLTS, JOHN D
FORD, LINCOLN E
FORD, LINCOLN E
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ALPHABETICAL LISTING OF INVtSIIGATORS
FORSTER, ROBERT E
FORSTER, ROY P
FORSYTH, RALPH P
FORTE, GERTRUDE M
FORTES, P A
FORTUIN, NICHOLAS J
FOSTER. JUDITH
FOSTER. JUDITH A
FOX. ARTHUR C
FOX, IRWIN J
FOX, MARTIN
FOZZARD, HARRY A
FOZZARD, HARRY A
FOZZARD, HARRY A
FOZZARD, HARRY A
FRANK, CHARLES
FRANKEL, HARRY M
FRANKLIN, DEAN
FRANKLIN, DEAN
FRANKLIN, DEAN L
FRANKLIN, THOMAS D,
FRANSON, RICHARD C
FRANTZ, IVAN D, JR
FRANZBLAU, CARI
FRANZBLAU, CARL
FRANZBLAU, CARL
FRANZBLAU, CARL
FRANZBLAU, CARL
FRASHER, WALLACE G,
FRAZIER, DONALD T
FREDBERG, JEFFREY J
FREDERIKSEN, DIXIE
FREDRICKS, WALTER W
FREED, CURT R
FREED, PAUL S
FREED, PAUL S
FREED, PAUL S
FREED, PAUL S
FREEOMAN, J C
FREEDMAN, J C
FREER, RICHARD J
FREER, RICHARD J
FREGA, NORBETO
FREGLY, MELVIN J
FREIMAN, DAVID G
FREIMER, EARL H
FREUNOLICH, IRWIN M
FRIED, WALTER
FRIEDMAN, GARY D
FRIEDMAN, HAROLD L
FRIEDMAN, JULIUS J
FRIEDMAN, JULIUS J
FRIEDMAN, MEYER
FRIEDMAN, MITCHELL
FRIEDMAN, MORTON H
FRIEDMAN, PAUL A
FRIEDMAN, PAUL A
FRIEDMAN, WILLIAM F
FRITZ, KATHERINE E
FROHLICH, EDWARD D
FROHLICH, EDWARD D
FROHLICH. EDWARD D
FROHLICH, EDWARD D
FROHLICH, EDWARD D
FROHLICH, EDWARD 0
FROLICH, JURGEN C
FRONEK, ARNOST
FRONEK, ARNOST
FRONEK, KITTY
FRONEK, KITTY
FROSOLONO, MICHAEL
FROSOLONO, MICHAEL
FROST, PHILIP
FROST, PHILIP H
FRYE, ROBERT C
FUCHS, JAMES C
FUHR, JOSEPH E
FUHRMAN, FREDERICK
FULGINITI, VINCENT
FULLER, ELLEN 0
FULLER, GEORGE C
FULLER, GERALD M
FULLERTON, DWIGHT S
FUNG, HO-LEUNG
FUNG, LESLIE W
FUNG, YUAN-CHENG B
FUNG, YUAN-CHENG B
FURCHGOn, ROBERT F
FURIE, BARBARA C
FURIE, BRUCE
FUSTER, VALENTIN
GABBAY, KENNETH H
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ALPHABETICAL LISTING OF INVESTIGATORS
GABUZDA, THOMAS G
GAENSLER, EDWARD A
GAENSLER, EDWARD A
GAENSLER, EDWARD A
GAENSLER, EDWARD A
GAENSLER, EDWARD A
GAENSLER, EDWARD A
GAENSLER, EDWARD A
GALANAKIS, DENNIS
GALDSTON, MORTON
GALE, ROBERT P
GALLA, JOHN H
GALLAGHER, JOHN J
GALLAGHER, JOHN J
GALLETTI, PIERRE M
GALLIE, THOMAS M
GALLOP, PAUL M
GALOSY, RICHARD A
GALPER, JONAS B
GAMBAL, DAVID
GAMBLE, WALTER J
GANGULY, PANKAJ
GANOTE, CHARLES E
GANZ, WILLIAM
GANZ, WILLIAM
GANZ, WILLIAM
GANZ, WILLIAM
GANZ, WILLIAM
GARANCIS, JOHN
GARCIA-PALMIERI, MA
GARO, ELIZABETH
GARDNER, RICHARD A
GARFINKEL. DAVID
GARRICK, R A
GARTNER, THEODORE K
GARVER, FREDERICK A
GARYN, WILNER
GASIC, GABRIEL J
GATZY, JOHN T, JR
GAUMER, H RICHARD
GAUNTT, CHARLES J
GAVRAS, HARALAMBOS
GAVRAS, HARALAMBOS
GAZES, PETER C
GEBBER, GERARD L
GEDDES, LESLIE A
GEE, J BERNARD
GEE, MARLYS H
GEHA, ALEXANDER S
GEIS, W PETER
GELBAND, HENRY
GELFAND, ROBERT
GELFAND, ROBERT
GELFAND, ROBERT
GELFAND, ROBERT
GELFAND, ROBERT
GELFAND, ROBERT
GELFAND, ROBERT
GENGOZIAN, NAZARETH
GENNIS, ROBERT B
GEORGE, JAMES N
GERALD, PARK S
GERATZ, J DIETER
GERGELY, JOHN
GERGELY, JOHN
GERMAN, JAMES
GERRITY, ROSS G
GERTNER, SHELDON B
GESELOWITZ, DAVID B
GEnES, LEONARD S
GETZ, GODFREY
GETZ, GODFREY S
GEYER, ROBERT
GEYER, ROBERT P
GEYER, ROBERT P
GEYER, ROBERT P
GHOSH, SANTIBRATA
GHOSH, SANTIBRATA
GIACHEni, ANTONIO
GIARDINA, ELSA GRAC
GIBBONS, WALTER R
GIBLETT, ELOISE R
GIDDENS, DON P
GIESE, WARREN K
GIL, JOAN
GILBERT, DAVID B
GILBERT, ENID F
GILES, WAYNE R
GILL, STANLEY J
GILLETTE, PAUL C
GILLIAM, JAMES M
GILLIS, CHARLES N
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GILLIS, CHARLES N
GILMAN, PRISCILLA A
OILMAN, PRISCILLA A
GILMORE, JOSEPH P
GILMORE, JOSEPH P
GILUU, NORTON B
GIMBRONE, MICHAEL A
GIMBRONE, MICHAEL A
GIMBRONE, MICHAEL A
GIRI, SHRI N
GITLOW, STANLEY E
GLAESER, DONALD H
GLAGOV, SEYMOUR
GLAGOV, SEYMOUR
GLASER, CHARLES B
GLASS, DAVID C
GLASS, RICHARD S
CLASSMAN, EPHRAIM
GLAUSER, FREDERICK
GLEISNER, JOHN M
GLENN, WILLIAM W
GLEW, ROBERT H
GLEZEN, WILLIAM P
GLOMSET, JOHN A
GODLEY, ALEGRO J
GODMAN, GABRIEL C
GODMAN, GABRIEL C
GOEDKEN, VIRGIL L
GOERKE, R JON, III
GOETZ, KENNETH L
GOETZL, EDWARD J
GOLD, HERMAN K
GOLD, HERMAN K
GOLD, HERMAN K
GOLD, WARREN M
GOLD, WARREN M
GOLDBERG, ALAN D
GOLDBERG, BURTON D
GOLDBERG, MARTIN
GOLDBERG, MORTON F
GOLDBERG, NELSON
GOLDE, DAVID W
GOLDFARB, ROY D
GOLDFISCHER, SIDNEY
GOLDINGER, J M
GOLDMAN, MICHAEL D
GOLDRING, DAVID
GOLDSTEIN, BERNARD
GOLDSTEIN, GARY W
GOLDSTEIN, JOSEPH L
GOLDSTEIN, JOSEPH L
GOLDSTEIN, MARGARET
GOLDSTEIN, MARGARET
GOLDSTEIN, MARGARET
GOLDSTEIN, SIDNEY
GOLDSTICK, THOMAS K
GOLDWASSER, EUGENE
GOLOWASSER, EUGENE
GOLL, DARREL E
GOLLNICK, PHILIP D
GOMEZ-SANCHEZ, CELS
GOMEZ-SANCHEZ, CELS
GONNERMAN, WAYNE
GOODFRIEND, THEODOR
GOODMAN, DE WITT S
GOODMAN, DEWITT S
GOODMAN, DEWin S
GOODMAN, DEWITT S
GOODMAN, DEWin S
GOODMAN, MURRAY
GOODNIGHT, SCOTT
GOOTMAN, PHYLLIS M
GORDON, ALBERT S
GORDON, MICHAEL S
GORE, ROBERT W
GORE, ROBERT W
GORIN, ARNOLD B
GORRY, G ANTHONY
GOSPODAROWICZ, DENI
GOSSELIN, ARTHUR J
GOTSHALL, ROBERT W
GOn, VINCENT L
GOnSCHALK, CARL W
GOULD, KENNETH L
GOULD, KENNETH L
GRAHAM, JOHN B
GRAHAM, JOHN B
GRAHAM, THOMAS P, J
GRAHAM, WILLIAM G
GRAHAM, WILLIAM G
GRAMBSCH, P VICTOR
GRAMIAK, RAYMOND
590
R01HL23245-01
P60HL1 5 158-07 0004
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R01HL13427-09
R01HL17902-04
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R01HL20054-02
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R01HL04651-19
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R01HL19651-03
R01HL10642-18
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R01HL20996-02
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R01HL19777-03
P50HL1 7665-04 0002
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R01HL18527-03
R01HL18730-03
R01HL21779-01
P01HL19717-02 0002
R01HL19836-03
P50HL2 1006-02
P50HL14236-05 0001
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P01HL18576-03 0003
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R01HL20864-01
R01HL03357-21
N01HV62969-03
R01HL13437-09
P01HL17421-05 0003
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P01HL06350-17
P01HL06350-17 0015
R01HL21985-01
P50HL14212-07 0001
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N01HV62941-01
R01HL15016-07
GRAMIAK, RAYMOND
GRANGER, HARRIS J
GRANT, MARGARET M
GRAUSZ, JOHN P
GRAY, BEUWH H
GRAY, ERNEST D
GRAY, MARY E
GRAY, RICHARD
GRAY. RICHARD
GREASER, MARION L
GREEN, HAROLD D
GREEN, HAROLD D
GREEN, HARRY L
GREEN, JERRY F
GREEN, LAWRENCE W
GREENBAUM, LOWELL
M
GREENBAUM, LOWELL
M
GREENBERG, LEONARD
GREENBERG, MICHAEL
GREENBERG, STANLEY
GREENBERG, STANLEY
GREENE, DAVID G
GREENFIELD, JOSEPH
GREENFIELD, JOSEPH
GREENFIELD, JOSEPH
GREENFIELD, JOSEPH
GREENWALT, TIBOR J
GREER, JONATHAN
GREGA, GEORGE J
GREGORY, JOHN J
GREISS, FRANK C, JR
GREKIN, ROGER J
GREKIN, ROGER J
GRIFFIN, JOHN H
GRIFFIN, PAUL M
GRIFFITH, LAWRENCE
GRIGGS, DOUGLAS M,
GRIM, CLARENCE E
GRIM, CWRENCE E
GRIM, CLARENCE E
GRIM, CLARENCE E
GRODINS, FRED S
GROSS, IAN
GROSS, JOSEPH F
GROSS, JOSEPH F
GROSSMAN, WILLIAM
GROSSMAN, WILLIAM
GROVERJOHNSON, NIC
GROVER, JOHN
GROVER, ROBERT F
GROVER, ROBERT F
GROVER, ROBERT F
GROVER, ROBERT F
GROVER, ROBERT F
GROVER, ROBERT F
GRUENSTEIN, ERIC I
GRUMET, F CARL
GRUNDY, scon M
GRUNDY, scon M
GRUPPO, RALPH A
GRUPPO, RALPH A
GUIDOni, GUIDO
GUNN, ROBERT B
GUNN, ROBERT B
GURD, FRANK R
GURD, FRANK R
GUREWICH, VICTOR
GURTNER, GAIL H
GUTHRIE, GORDON P,
GUTHRIE, HELEN A
GUTHRIE, ROBERT D
GUTNISKY, ABRAHAM
GUTSTEIN, WILLIAM H
GUYTON, ARTHUR C
GUYTON, ARTHUR C
GUYTON, ARTHUR C
GWYNNE, JOHN T
HAAS, ERWIN
HABAL, SALEM
HABER, EDGAR
HABER, EDGAR
HABER, EDGAR
HABER, EDGAR
HACKEL, DONALD B
HACKEL, DONALD B
HACKEL, DONALD B
HACKETT, THOMAS P
HADDY, FRANCIS J
HAGEN, PER-OnO F
HALASZ, NICHOLAS A
ROIHL 16260-04
R01HL2 1498-02
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R01HL22636-01
P01HL06314-17 0046
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I
HALL. CHARLES E
HALL. CHARLES E
HALL. lAMES E
HALL. JOHN E
HALL. JOHN E
HALONEN. MARILYN J
HALPERN. WILLIAM
HAMES. CURTIS G
HAMES. CURTIS G
HAMILTON. GLEN W
HAMILTON. ROBERT L
HAMMOND. GRAEME L
HAMOSH. MARGIT
HAMOUDA. FAROUK A
HAMOUOA, FAROUK A
HAMRELL. BURT B
HAN. JAOK
HANAHAN, DONALD J
HANCE. ALLAN J
HANDIN, ROBERT I
HANSEN. TIMOTHY R
HANSON. KENNETH M
HARAKAL. CONCEIT A
HARBURY. CHRISTINA
HAR6URY, CHRISTINA
HARDEN, T KENDALL
HARDIN. JAMES
HARDMAN. HAROLD F
HARDY. JANET B
HARDY. ROBERT J
HARELL. GEORGE S
HARING. OLGA M
HARKEN, ALDEN H
HARKER, LAURENCE
HARKER. LAURENCE A
HARKER, LAURENCE A
HARKNESS, DONALD R
HARKNESS, DONALD R
HARKNESS. DONALD R
HARMONY, JUDITH A
HARPEL, PETER C
HARPER, ELVIN
HARPER, ELVIN
HARPER, PAUL V
HARPER. RONALD M
HARRINGTON, JOHN
HARRIS, ALAN H
HARRIS, DANIEL C
HARRIS, HERMAN F
HARRIS, HERMAN F
HARRIS, PATRICK D
HARRIS, THOMAS R
HARRIS, THOMAS R
HARRIS, THOMAS R
HARRIS, THOMAS R
HARRIS. WILLIAM H
HARRISON. CARLOS E,
HARRISON. DAVID E
HARRISON. DONALD C
HARRISON. JOHN H
HARRISON, TIMOTHY S
HARRISON, WALTER K
HARRISON, WALTER K
HART, BETH A
HART, MICHAEL N
HARTLEY, CRAIG J
HARTLEY. L HOWARD
HARTLEY. LOREN H
HARTMANN, ROBERT C
HARTSHORNE, DAVID J
HARTSHORNE, DAVID J
HARTZELL, CHARLES R
HARTZELL, HARRISON
HARVATH. LIANA
HARVEY, REJANE M
HARVIE. NANCY R
HARWIG. JOHN F
HASCHEMEYER. RUDY H
HASHIMOTO, SAM
HASS, LOUIS F
HATCHER, VICTOR
HATHAWAY, WILLIAM E
HATHAWAY, WILLIAM E
HATHAWAY, WILLIAM E
HAUBOLD, A D
HAUGAARD. NIELS
HAUGAARD, NIELS
HAVEL, RICHARD J
HAVEL, RICHARD J
HAVEL, RICHARD J
HAVEL, RICHARD J
HAVEL, RICHARD J
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P50HL14237-07 0005
HAVEL, RICHARD J
HAWIGER. JACK J
HAWKINS. MORION C
HAWKINS. MORTON C
HAWKRIDGE. FRED M
HAWTHORNE, EDWARD
W
HAY. ROBERT J
HAYES. KENNETH C
HAYES. ROBERT G
HAYNES. DUNCAN
HAYNES. DUNCAN H
HAYWOOD. L JULIAN
HAYWOOD, L JULIAN
HAYWOOD, L JULIAN
HAZZARD, WILLIAM R
HAZZARD. WILLIAM R
HEADINGS, VERLE E
HEATH, MILAN J
HEBBEL, ROBERT P
HEBERT. LEE A
HEFNER. LLOYD L
HEFNER, LLOYD L
HEGYVARY, CSABA
HEINEMAN. HENRY 0
HEINEMANN. HENRY 0
HEINRIKSON, ROBERT
HEINRIKSON. ROBERT
HEISE. EUGENE R
HEISTAD, DONALD D
HEISTAD, DONALD D
HEISTAD. DONALD D
HEISTAD. DONALD D
HELLER, PAUL
HELLER, PAUL
HELLUMS, JESSE 0
HELLUMS. JESSE D
HEMENWAY. DAVID
HEMMINGSEN, EDVARD
HEMPEL, F G
HEMPEL. FRANK G
HENORICKSON, DAVID
HENRY. JAMES P
HENRY, PHILIP D
HENRY, PHILIP D
HENRY, PHILIP D
HENSON. PETER M
HEPTINSTALL. ROBERT
HEPTINSTALL, ROBERT
HERD, JAMES A
HERD, JAMES A
HERD, JAMES A
HERLIHY, JEREMIAH T
HERMAN, GABOR T
HERMANS, JAN
HERMSMEYER, KENT
HERMSMEYER, KENT
HERMSMEYER, R KENT
HERSCOWITZ, HERBERT
HERZIG, GEOFFREY P
HESS, MARILYN E
HESSEL, S J
HESSEL, S J
HESSEL, S J
HEWin. ROBERT L
HEYMANN. MICHAEL A
HEYMANN, MICHAEL A
HEYMANN, MICHAEL A
HIG6INS, MILLICENT
HIGGINS, MILLICENT
HIGHTOWER, LAWRENCE
HILAL, SADEK K
HILAL, SADEK K
HILBERMAN, MARK
HILDEBRANDT, JACOB
HILDEBRANDT, JACOB
HILDEBRANDT. JUDITH
HILGARTNER, MARGARE
HILL. ESTHER P
HILLER. F CHARLES
HILLMAN, ROBERT S
HILTNER, PHYLLIS A
HINKLE, LAWRENCE E,
HINKLE, PETER C
HINSHAW, LERNER B
HIRKO, ROBERT J
HIRSCH, LEROY J
HIRSHFELD, JOHN W,
HISKEY, RICHARD G
HISS, ROLAND
HISTAND, MICHAEL B
HITCHCOCK, KAREN R
591
P50HL1423707 0007
R01HL1664605
N01HVI2442 14
N01HV7294803
R01HL2282101
R01HL0101527
N01HR62930-03
R01HL1579705
R01HL1365107
P01HL16117-05 0003
R01HL2339201
P60HL1 516207
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R01HL15607-06
R01HL18683-03
R01HL20161-02
N01HR62931-02
R01HL22326-01
R01HL15316-07
AlPHABETICAl LISTING Of INVESTIGATORS
HLASIALA. MICHAEL P
HO. CHIEN
HOAK. JOHN C
HOAK. JOHN C
HOAK, JOHN C
HOCHMUTH, ROBERT M
HODGES. MORRISON
HODGINS, LEONARD T
HODGKIN. BRIAN C
HOOGKIN. JOHN E
HODSON. CECIL J
HODSON. WILLIAM A
HODSON. WILLIAM A
HOEVE, CORNELIS A
HOFF. HENRY F
HOFFMAN. ALLAN S
HOFFMAN. BRIAN F
HOFFMAN. BRIAN F
HOFFMAN. BRIAN F
HOFFMAN, BRIAN F
HOFFMAN, BRIAN F
HOFFMAN. BRIAN M
HOFFMAN. JOSEPH F
HOFFMAN, JULIEN I
HOGAN, PERRY
HOGAN, PERRY M
HOGAN. PERRY M
HOHN, ARNO R
HOKIN, LOWELL E
HOLDEN, DOROTHY M
HOLOEN, DOROTHY M
HOLDEN, DOROTHY M
HOLDEN, DOROTHY M
HOLE, JAMES E
HOLLANDER, PHILIP B
HOLLANDER, WILLIAM
HOLLANDER, WILLIAM
HOLLANDER. WILLIAM
HOLLENBERG, MILTON
HOLLENBERG. MILTON
HOLLENBERG, NORMAN
HOLLENBERG, NORMAN
HOLLIFIELD, JOHN W
HOLLIS, DONALD P
HOLLIS, THEODORE M
HOLLIS, THEODORE M
HOLLOSZY, JOHN 0
HOLLOWAY, CAROLINE
HOLLOWAY, PETER W
HOLMAN, B L
HOLMAN, B LEONARD
HOLMAN, RALPH T
HOLMAN. RALPH T
HOLMAN, RALPH T
HOLMES DAVID R
HOLMES, WILLIAM L
HOLMES, WILLIAM L
HOLMSEN, HOLM
HOLT, JOHN H
HOLTZER, HOWARD
HOLTZER, HOWARD
HOLTZER, HOWARD
HOMSHER, EARL
HOMSHER, EARL E
HOMSHER, EARL E
HONDEGHEM, LUC M
HONIG, CARL R
HONIG, GEORGE R
HOOD, WILLIAM B, JR
HOOD, WILLIAM B, JR
HOOD, WILLIAM B, JR
HOOD, WILLIAM P
HOOD. WILLIAM P
HOPEWELL, PHILLIP C
HOPPIN, FREDERIC G
HOPPIN, FREDERIC G
HORAN, LEO G
HORBEn. THOMAS A
HORBEn, THOMAS A
HORNING, EVAN C
HOROWITZ, LEONARD N
HOROWITZ, MAROI J
HORRES, C R
HORTON, RICHARD
HORWITZ, LAWRENCE D
HOUGIE, CECIL
HOUGIE, CECIL
HOUGIE, CECIL
HOUGIE, CECIL
HOUSTON, CHARLES S
HOYER, LEON W
HOYER, LEON W
R01HL12I74 II
R01H11038312
P50HL 14230 07 0095
P50HL 14230 07 0096
P50HL1423007 0097
R01HL2390001
R01HL18I90 03
P01HL1559605 0020
ROIHL 19486 03
N01HR7290403
R01HL1979102
P50HLI918702
P50HL19187 02 0001
ROIHL 1844 103
P60HL 1726904 0048
P01HL2216301
R01HL0850815
P01HL1273810
P01HL1273810 0110
P01HL1273810 0128
P01HL1273810 0132
R01HL1353106
R01HL0990613
P01HL06285-18 0143
P01HL15194-07 0004
P01HL1441407 0010
R01HL16135-05
R01HL19870-03
R01HL16318-21
P60HL151 70-05 0001
P60HL15170-05 0002
P60HL15170-05 0003
P60HL15170-05 0030
R01HL22873-01
R01HL20153-02
P01HL13262-07
P01HL13262-07 0011
R01HL1643705
P01HL06285-18 0179
R01HL2266401
R01HL14944-07
R01HL20895-03 0010
P50HL1419208 0005
R01HL22080-01
R01HL19830-02
R01HL20460-03
R01HL22215-01
R01HL19936-02
P01HL19242-02 0002
R01HL20895-03 0002
R01HL17739-04
P01HL08214-15
P01HL08214-15 0006
R01HL21513-02
P60HL17292-04 0024
N01HV33110-04
N01HV72958-02
P50HL14217-08 0059
P01HL11310-12 0093
P01HL15835-06 0009
P01HL18708-03 0007
P01HL18708-03 0008
POIHLI 1351-12 0006
P01HL11351-12 0021
P01HL11351-12 0024
R01HL21672-01
R01HL03290-22
P60HL15168-07 0010
R01HL14646-05
P50HL18318-03 0010
P50HL18318-03 0018
P01HL11310-12 0081
P50HL17667-04 0039
N01HR72906-03
P01HL14580-07 0001
P50HL19170-02 0006
R01HL16901-05
R01HL1941903
P01HL22163-01 0001
P60HL1 7269-04 0016
R23HL21292-01
R01HL17580-04
P01HL12157-11 0056
R01HL2 11 12-02
R01HL16656-06
R01HL15230-05
P01HL18576-03 0005
P01HL18576-03 0009
R01HL19272-03
R01HL14102-07
R01HL16626-05
R01HL16872-04
ALPHABETICAL LISTING OF INVESTIGATORS
HOYT, RICHARD F, JR
HRUBEC, ZDENEK
HSIA, S L
HSIA, S L
HSIA, SUNG L
HUANG, PENG Y
HUESTIS, WRAY H
HUFFMAN, ANN
HUGGINS, CLYDE G
HUGHES, HOWARD C
HUGHES, MAYSIE J
HUGHES, WALTER
HUGLI, TONY E
HUGLI, TONY E
HUISMAN, TITUS H
HUISMAN, TITUS H
HUISMAN, TITUS H J
HUISMAN, TITUS H J
HUISMAN, TITUS H J
HULL, FRANKLIN E
HULLEY, STEPHEN B
HUMPHREY, EDWARD W
HUMPHREYS, MICHAEL
HUMPHRIES, J ONEAL
HUNT, CHARLES
HUNTLEY, THOMAS E
HUNTSMAN, LEE L
HUNTSMAN, LEE L
HUTCHINS, GROVER M
HUTCHINS, GROVER M
HUTCHINS, GROVER M
HUTCHINS, PHILLIP M
HUTCHISON, VICTOR H
HUnER, ADOLPH M
HUTTER, ADOLPH M
HUXTABLE, RYAN J
HUXTABLE, RYAN J
HYATT, ROBERT E
HYAn, ROBERT E
HYAH, ROBERT E
HYDE, RICHARD W
HYMAN, ALBERT L
HYMAN, MARTIN D
IBBOTT, FRANK A
IBERS, JAMES A
IMAI, HIDESHIGE
IMPARATO, ANTHONY M
IMPARATO, ANTHONY M
INAGAMI, TADASHI
INAGAMI, TADASHI
INDYK, LEONARD
INESI, GIUSEPPE
INESI, GIUSEPPE
INGEBRETSEN, WILLIA
INGELS, NEIL B, JR
INGELS, NEIL B, JR
INGELS, NEIL B, JR
INGELS, NEIL B, JR
INGELS, NEIL B, JR
INGELS, NEIL B, JR
INGHAM, KENNETH C
INGRAM, F DUANE
INGRAM, ROLAND H, J
INGRAM, ROLAND H, J
INGWALL, JOANNE S
INGWALL, JOANNE S
INGWALL, JOANNE S
INNERARITY, THOMAS
INSULL, W
INSULL, WILLIAM
INSULL, WILLIAM, JR
INTAGLIETTA, MARCOS
INTAGLIETTA, MARCOS
IRELAND, ROBERT E
ISACSON, PETER
ISHIMARU, AKIRA
ISHIMARU, AKIRA
ITADA, NOBUTOMO
ITSKOVITZ, HAROLD D
IWAI, JUNICHI
IWAI, JUNICHI
IYENGAR, M RAJA
IYENGAR, MELKOTE R
JACKSON, ANDREW C
JACKSON, CARL W
JACKSON, CRAIG M
JACKSON, CRAIG M
JACKSON, RICHARD
JACKSON, RICHARD L
JACKSON, ROBERT L
JACKSON, THOMAS E
JACOB, HARRY S
R01HL19379
N01HV53010
P50HL14141-
P50HL14141
R01HL20418
R01HL09913
R01HL18660
P60HL15996-
R01HL15567
R01HL13988
R01HL16240
P50HL19157
P01HL16411
R01HL20220
R01HL05168
P60HL15158-
P60HL15158
P60HL15158
P60HL15158-
R01HL14730
N01HV22981
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P50HL17655
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R01HL20411
R01HL16830
R01HL20613
P50HL14153
P50HLI7655
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R01HL13936
R01HL18082
P50HL17665
P50HL17665
R01HL19394
R01HL20087
P01HL21584
P01HL21584
P01HL21584
R01HL16784
R01HL11802
P50HL14236
N01HV72950
R01HL13157
P01HL20993
R01HL22783
R01HL22784
P50HL14192
R01HL22288
P50HL14218
P01HL16607
P01HL16607-
R01HL22064
R0IHLI7993
R01HL17993
R01HL17993
R01HL17993
R01HL17993
R01HLI7993
R01HL21791
P01HL14388
R01HL16463
P50HL19170
P01HL20552
R01HL2I751
R01HL22290
N01HI32926
P50HL14236
N01HV12156
R01HL22847-
R01HL12493-
P01HL17421
R01HL21367
P01HL14388
R01HL19993
P01HL22163-
P01HL19737
R01HL12677
R01HL13408
R01HL14913
P01HL15835
R01HL22538
R01HL22178
R01HL19270
R01HL12820
P50HL14147-
P01HL22619-
P60HL17269
R01HL13632
P01HL11678
P01HL16833
■03
-03
•05 0003
•05 0008
■03
■13
■03
06 0004
-05
-07
-05
■02 0011
04 0005
■03
■19
07
•07 0008
•07 0016
07 0028
■07
■10
-03
-01
■04 0004
•02
■03
■05
-02
■07 0019
04 0010
■01
■06
•03
■04 0013
■04 0018
-03
-02
■02
■02 0004
•02 0006
■03
■10
05 0013
1-02
-09
■02 0008
-01
-01
■08 0004
-01
■07 0013
05
05 0003
•02
1-04
•04 0006
-04 0007
-04 0008
■04 0009
-04 0010
•01
■07 9003
-05
-02 0003
■02 0010
-02 0001
-01
10
05 0012
-10
-01
-10
■05 0007
-02
-07 9004
-02
•01 0002
•02 0012
-10
•05
■06
■06 0002
-01
-01
-03
■09
08 0003
■01 0011
04 0011
■08
■11 0051
■04 0014
JACOB, HARRY S
JACOBS, H KURT
JACOBS, JOHN E
JACOBS, JOHN E
JACOBSON, HOWARD N
JACOBSTEIN, JEROME
JACOBUS, WILLIAM E
JAEGER, RUDOLPH J
JAFFE, ERIC A
JAKAB, GEORGE J
JAKSCHIK, SISTER BA
JAMES, FREDERICK W
JAMES, HAROLD
JAMES, L STANLEY
JAMES, L STANLEY
JAMES, L STANLEY
JAMES, THOMAS N
JAMES, THOMAS N
JAMES, THOMAS N
JAMES, THOMAS N
JAMES, THOMAS N
JAMES, THOMAS N
JAMES, THOMAS N
JAMIESON, GRAHAM A
JAMIESON, GRAHAM A
JAN, KUNGMING
JANDL, JAMES H
JANIS, RONALD A
JANOFF, AARON
JANZ, RONALD F
JARMAKANI, JAY M
JARVIK, ROBERT K
JAVID, JAMSHID
JELLINEK, MAX
JELLINEK, MAX
JELLINEK, MAX
JENG, INGMING
JENKIN, HOWARD M
JENKINS, C DAVID
JENKINS, C DAVID
JENNINGS, ROBERT B
JENNINGS, ROBERT B
JENSEN, RICHARD A
JENSEN, ROBERT G
JESSE, MARY J
JESSE, MARY JANE
JESTY, JOLYON
JEW, JEAN Y
JIMENEZ, SERGIO A
JOH, TONG H
JOH, TONG H
JOH, TONG H
JOH, TONG H
JOHANSON, WALDEMAR
JOHNSON, ALAN J
JOHNSON, ALAN J
JOHNSON, ALAN J
JOHNSON, ALICE R
JOHNSON, B CONNOR
JOHNSON, CARL L
JOHNSON, CHARLES E
JOHNSON, CHARLES E
JOHNSON, DALE E
JOHNSON, E A
JOHNSON, E A
JOHNSON, E A
JOHNSON, E A
JOHNSON, E A
JOHNSON, E A
JOHNSON, E A
JOHNSON, EDWARD A
JOHNSON, EUGENE M,
JOHNSON, GEORGE, JR
JOHNSON, JOHN M
JOHNSON, JOSEPH A
JOHNSON, JOSEPH E
JOHNSON, LARRY R
JOHNSON, MICHAEL E
JOHNSON, PAUL C
JOHNSON, PAUL C
JOHNSON, PAUL C
JOHNSON, PAUL C
JOHNSON, PETER
JOHNSON, ROBERT A
JOHNSON, ROBERT L
JOHNSON, ROBERT L
JOHNSON, ROBERT L
JOHNSON, ROBERT M
JOHNSON, ROBERT M
JOHNSON, STEVE L
JOHNSON, STEVE L
JOHNSON, STEVE L
592
R01HL19725-03
P01HL08682-15 0031
R01HL17769-03
R01HL22604-01
N01HV4292908
R01HL21684-02 0001
R01HL20658-01
P50HL19170-02 0005
P50HL18828-03 0002
R01HL22029-02
R01HL21874-01
R01HL18454-03
P01HL20994-02 9001
P50HL14218-07
P50HL14218-07 0011
P50HL14218-07 0012
P01HL11310-12
P01HL11310-12 0087
P01HL11310-12 0089
P01HL11310-12 0090
P01HL11310-12 9001
POIHLI 1310-12 9002
P50HL17667-04 0031
R01HL14697-07
R01HL20971-10
P01HL16851-04 0008
R01HL07652-14
R01HL21030-01
R01HL14262-07
R01HL14651-05
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N01HV72975-02
R01HL19646-03
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P50HL18318-03 0012
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P50HL1 7670-04 0023
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R01HL19076-03
R01HL16807-02
P50HL14141-05
P50HL14141-05 0001
R01HL21113-01
R23HL21914-01
P01HL18827-02 0002
P01HL18974-03 0009
P01HL18974-03 0010
P01HL18974-03 0011
P01HL18974-03 0015
P50HL19362-02 0008
P01HL15596-05
POIHLI 5596-05 0010
P01HL15596-05 0016
R01HL18826-04
R01HL12138-08
R01HL22136-02
P01HL07896-15 0036
R01HL19352-03
R01HL21371-02
P01HL11307-12 0003
P01HL12157-11 0037
P01HL12157-11 0049
P01HL12157-11 0052
P01HL12157-11 0054
P01HL12157-11 0058
P01HL12157-11 0060
P01HL12157-11
R01HL20604-03
R01HL20177-02
R01HL20663-02
R01HL17366-05
P01HL16769-05 0008
R23HL20576-01
P60HL15168-07 0009
R01HL15390-12
P01HL17421-05
P01HL17421-05 0004
P01HL17421-05 0006
R01HL23233-01
R01HL22750-01
P01HL06296-18 0002
P50HL14187-07 0015
R01HL20095-03
R01HL15793-06
P60HL16008-06 0018
P01HL07293-17 0051
P01HL07293-17 0052
P01HL07293-17 0059
JOIST, JOHANN H
JOKELAINEN, PENni
JOKELAINER, PENH!
JOKELAINER, PENni
JONAS, ANA
JONES, ALLAN W
JONES, CARL E
JONES, CYRIL J
JONES, DAVID B
JONES, JANICE L
JONES, JIMMY B
JONES, JOHN W
JONES, PERRY
JONES, RICHARD T
JONES, ROBERT H
JONES, ROBERT H
JONES, ROBERT N
JONES, STEVEN B
JONES, WARREN C, JR
JOSEPHS, ROBERT
JOYNER, RONALD W
JOYNER, WILLIAM L
JUCHAU, MONT R
JUDKINS, MELVIN P
JUDY, JESSE N
JULIAN, FRED J
JULIUS, STEVO
JUNGMANN, RICHARD A
JURATSCH, CRAIG E
KADOWITZ, PHILIP J
KADOWITZ, PHILIP J
KAFER, ENID R
KAGAN, HERBERT M
KAGAN, HERBERT M
KAGAN, HERBERT M
KAISER, EMIL T
KAISER, GEORGE C
KAISER, GEORGE C
KAISER, GEORGE C
KALIA, MADHU
KALNITSKY, GEORGE
KAMPINE, JOHN P
KAN, YUET WAI
KAN, YUET WAI
KANE, JOHN P
KANE, JOHN P
KANG, ANDREW H
KANG, ANDREW H
KANTROWITZ, ADRIAN
KANTROWITZ, ADRIAN
KANTROWITZ, ADRIAN
KANTROWITZ, ADRIAN
KANTROWITZ, ADRIAN
KAPLAN, EDWARD L
KAPUN, EDWARD M
KAPUN, EDWARD M
KAPWN, HARRY A
KAPLAN, J H
KAPWN, JEROME I
KAPLAN, JERRY
KAPLAN, KAREN L
KARDOS, J L
KARIC, LUCIJA STANC
KARIS, JOANNES H
KARLINER, JOEL S
KARLINER, JOEL S
KARLINER, JOEL S
KARLINSKY, JOEL B
KARLINSKY, JOEL B
KARLINSKY, JOEL B
KARLINSKY, JOEL B
KARNOVSKY, MORRIS J
KARNOVSKY, MORRIS J
KARPATKIN, SIMON
KASHYAP, M L
KASHYAP, MOTI L
KASHYAP, MOTI L
KASS, EDWARD H
KASS, EDWARD H
KASS, ROBERT S
KATONA, PETER G
KATZ, ARNOLD M
KATZ, ARNOLD M
KATZ, SIDNEY
KATZ, SOLOMON H
KATZUNG, BERTRAM G
KAUFFMAN, JOHN W
KAVALER, FREDERIC
KAY, MARGUERITE M B
KAYDEN, HERBERT J
KAYE, MICHAEL P
KAYE, MICHAEL P
P50HL14147-08 0017
R01HL18831-03
P01HL18575-03 0007
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R01HL16059-06
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R01HL20286-02
P60HL1 5 170-05
R01HL04300-20
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ROIHL 1564 7-06
N01HV22939-12
P60HL 16008-06 0011
R01HL20142-02
P50HL17670-04 0015
R01HL20677-02
P50HL15092-07 0012
P01HL08682-15 0006
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R01HL22654-01
R01HL22 562-02
R01HL19455-03
P01HL031 74-23 0011
NG1HV32975-08
N01HI72900-01
R01HL16606-11
R01HL21893-01
R01HL18682-03
R01HL18371-03
R01HL15580-06
R01HL18070-04
R01HL17314-04
P01HL13262-07 0015
P01HL19717-02 0004
P01HL19717-02 0005
P01HL18577-03 0005
P01HL06312-17 0013
P01HL06312-17 0053
N01HV32980-07
R01HL17800-04
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R01HL16511-04
P60HL20985-01 0005
P60HL20985-01 0010
P50HL14237-07 0003
P50HL14237-07 0006
R01HL19731-03
R01HL201 14-02
P01HL13737-07
P01HL13737-07 0028
P01HL13737-07 0029
P01HL13737-07 0032
R01HL2232901
R01HL19307-03
P50HL1 7665-04 0030
N01HV53027-05
R01HL19053-03
R01HL09906-13 0018
R01HL2 1706-02
R01HL21 120-02
P01HL15486-06 0005
N01HV72919-01
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R01HL09125-14
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P01HL22619-01 0012
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R01HL1986903
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R01HL22445-01
I
KEAN. CHARLES J C
KEAN. CHARLES J C
KEARNEY. EDNA B
KEARNEY, EDNA B
KEELY. STANLEY L. J
KEFALIOES, NICHOLAS
KEFALIOIES, NICHOLE
KEISER. )OHN M
KEISER. JOHN M
KELLEHER. PHILIP C
KELLER, KENNETH H
KELLEY, lASON
KELLNER, AARON
KELLY, A PAUL
KELLY, ALAN M
KEM, DAVID C
KEMP. HARVEY G
KENORICK. JOHN E
KENNEY, WILLIAM C
KENNEY. WILLIAM C
KERBER, RICHARD E
KEYES, JOHN W, JR
KEYS. ANCEL
KEZDI, PAUL
KEZDY, FERENC J
KEZDY, FERENCZ J
KHACHADURIAN. AVEOI
KHALIFAH. RAJA G
KHAW, BAN AN
KIDO, PARRIS M
KIM, DONG N
KIM, SUNG-WAN
KIM, SUNGWAN
KIMBEL, PHILIP
KIMBEL. PHILIP
KING, RICHARD J
KING, RICHARD J
KING, TSOO E
KING. WILLIAM S
KINGDON, HENRY S
KINGDON, HENRY S
KINIAS, PLATO
KIRBY, ALBERT C
KIRBY, EDWARD P
KIRBY, EDWARD P
KIRCHBERGER, MADELE
KIRK, EDWARD S
KIRKLIN, JOHN W
KIRKLIN, JOHN W
KIRKLIN, JOHN W
KIRKLIN, JOHN W
KIRKPATRICK, FRANCE
KIRKPATRICK, FRANCI
KIRKPATRICK, FRANCI
KIRPEKAR, S M
KIRSCHENBAUM, MICHA
KIRSTEN, EDWARD B
KISKER, C THOMAS
KITE, JOSEPH H, JR
KITTERMAN, JOSEPH A
KJELSBERG, MARCUS
KLEIN, DAVID H
KLEINERMAN, JEROME
KLEIN2ELLER, ARNOST
KLINE, DANIEL L
KLIP, WILLIAM
KLM, DONG N
KLOCKE, FRANCIS J
KLOCKE, FRANCIS J
KLOCKE, FRANCIS J
KLOCKE, FRANCIS J
KLOCKE, FRANCIS J
KLOCKE, FRANCIS J
KLOCKE, FRANCIS J
KLOCKE, ROBERT A
KLOCKE, ROBERT A
KLOCKE, ROBERT A
KLOCKE, ROBERT A
KLOCKE, ROBERT A
KLOSTER, FRANK E
KLOTZ, IRVING M
KNAUSS, THOMAS A
KNIGHT, DAVID H
KNOEBEL, SUZANNE B
KNOX, CHARLES K
KNOX, FRANKLYN G
KNUDSON, RONALD J
KNUDSON, RONALD J
KNYCH, EDWARD T, JR
KOCAN, RICHARD M
KOCSIS, JAMES J
KOEHLER, KARL A
P01HL1135112 0022
POIHLI 1351 12 0023
P01HL16251 06 0003
P01HL16251 06 0004
R01HL1918102
P50HL 15061 07 0004
P01HL18827 02 0001
N01HV5300807
N01HV7297602
P50HL14212 07 0004
P01HL1683304 0009
R23HL21504 02
P01HL09011 15
P60HL2328201 0003
POIHL 1583506 0010
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P01HL1625106 0001
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P50HL1 7648-04 0033
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P50HL142 17-08 0062
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ROIHLI 5764-05
R0IHL2317101
P01HL1I310-12 0056
P01HL11310-I2 0059
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P01HL18208-04 0007
P0IHLI8208-04 0003
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P01HL12738-10 0109
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P50HL19185-02 0003
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POIHLI 5194-07 0023
R01HL21293-02
R01HL08299-16
P50HL19187-02 0011
P01HL08805-15 0049
P01HL06308-18 0011
R01HL16430-05
R01HL14133-08
P50HL14136-07 0001
P50HL14136-07 9002
R01HL18893-03
P01HL03174-23 0010
R01HL20211-02
R01HL18245-03
KOHN. ROBERT M
KOIVO. ANni J
KOLBECK, RALPH C
KOLER, ROBERT D
KOLETSKY, SIMON
KOLFF, WILLEM J
KOLFF, WILLIAM )
KOLFF. WILLIAM J
KOLIN, ALEXANDER
KONTOS. HERMES A
KOOYMAN, GERALD L
KOROENAT, R KARL
KOSHY, MABEL
KOSHY, MABEL
KOSOW. DAVID P
KOSOW, DAVID P
KOSTREVA, DAVID R
KOTCHEN, JANE M
KOTCHEN, THEODORE A
KOTCHEN, THEODORE A
KOnKE, BRUCE A
KOUCHOUKOS, NICHOLA
KOUCHOUKOS, NICHOU
KOUCHOUKOS, NICHOLA
KOUCHOUKOS, NICHOLA
KOUCHOUKOS, NICHOLA
KOUSHANPOUR, ESMAIL
KOZmOWSKI, ALAN P
KRAEMER, DUANE C
KRAEMER, DUANE C
KRAEMER, DUANE C
KRAKOFF, LAWRENCE R
KRAKOWER, CECIL A
KRALIOS, FANY A
KRAMER, ROBERT J
KRAMSCH, DIETER M
KRAMSCH, DIETER M
KRAMSCH, DIETER M
KRAMSCH, DIETER M
KRASNE, SALLY J
KRASNEY, JOHN
KRAUS, ALFRED P
KRAUS, ALFRED P
KRAUS, ALFRED P
KRAUS, JESS F
KRAUS, LORRAINE M
KRAUSS, RONALD M
KREGER, ARNOLD S
KRESS, LAWRENCE F
KREUTZER, DONALD L
KRIMM, SAMUEL
KRIPPAEHNE, WILLIAM
KRITCHEVSKY, DAVID
KRITCHEVSKY, DAVID
KRITCHEVSKY, DAVID
KRIVIT. WILLIAM
KROL, WILLIAM F
KRON, REUBEN E
KRON, REUBEN E
KRONAUER, RICHARD E
KRONENBERG, MARVIN
KRONGRAD, EHUD
KRONGRAD, EHUD
KRONICK, PAUL L
KROPP, DONNA L
KRUEGER, DEAN E
KRUEGER, JOHN W
KRUGER, FRED A
KUEHL, KAREN S
KUEPPERS, FRIEDRICH
KUEPPERS, FRIEDRICH
KUHN, CHARLES
KUHN, CHARLES, III
KULLER, LEWIS H
KULLER, LEWIS H
KULLER, LEWIS H
KUMAR, SURIENDER
KUMMEROW, FRED A
KUN, ERNEST
KUNAU, ROBERT T, JR
KUNZ, ALBERT L
KUNZE, DIANA L
KUO, JYH-FA
KUO, PETER T
KURUP, VISWANATH P
KUTCHAI, HOWARD C
KVALE, PAUL A
KWAN-GETT, CLIFFORD
KWIATKOWSKI, G. T.
KWITEROVICH, PETER
KWITEROVICH, PETER
KYLSTRA, JOHANNES A
593
N01HV72952-02
R01HL2241701
R01HL167I003
R01HL20393-03
R01HL2234101
P01HL1373808
POIHL 13 738-08 0002
R01HL2080302
R01HL1759103
R01HL2185101
P01HL17731 04 0003
R01HL2200501
P60HL1600505 0018
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P60HL15169-05 0018
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R01HL14126-17
R01HL03299-21
R01HL05209-18
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P01HL08899-14 0046
R01HL17408-03
R01HL16325-03
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P01HL12738-10 0127
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P01HL06285-18 0178
R01HL18875-03
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N01HV72968-03
P50HL15389-07 0019
R01HL17967-04
N01HR62944-04
P01HL13738-08 0004
N01HV32950-08
R01HL17898-03
N01HV12158-10
P01HL07896-15 0021
ALPHABETICAL LISTING OF INVESTIGATORS
KYTE, JACK E
LA CELLE. PAUL L
LA CELLE. PAUL L
LA LONE, BRIAN J
LA MAR, GERD N
LA ROSA. JOHN C
LABARTHE, DARWIN R
LACELLE. PAUL L
LADDA, ROGER L
LAFARGE. C GRANT
LAGE, GARY L
LAGUNOFF, DAVID
UGUNOFF, DAVID
LAHIRI. S
LAHIRI, S
LAHIRI, SUKHAMAY
LAI-FOOK, STEPHEN J
LAI, YIH-LOONG
LAING, RONALD A
LAKS, HILLEL
LAKS, MICHAEL M
LALEZARI, PARVIZ
LAMBERTH, EDWIN L
LAMBERTSEN, CHRISTI
LAMBERTSEN, CHRISTI
LAMBERTSEN, CHRISTI
LAMBERTSEN, CHRISTI
LAMBERTSEN. CHRISTI
LAMBERTSEN, CHRISTI
LAMBERTSEN, CHRISTI
LAMBERTSEN, CHRISTI
LAMBERTSEN, CHRISTI
LAMBERTSEN, CHRISTI
LAMBERTSEN, CHRISTI
LAMBERTSEN, CHRISTI
LAMBERTSEN, CHRISTI
LAMBERTSEN, CHRISTI
LAMBERTSEN, CHRISTI
LAMBERTSEN, CHRISTI
LAMBERTSEN, CHRISTI
LAMBERTSEN, CHRISTI
LAMBERTSEN, CHRISTI
LAMBERTSEN, CHRISTI
LAMBERTSON, CHRISTI
LAMBERTSON, CHRISTI
LAMBERTSON, CHRISTI
LAMBERTSON, CHRISTI
LAMBERTSON, CHRISTI
LAMBERTSON, CHRISTI
LAMBERTSON, CHRISTI
LAMBERTSON, CHRISTI
LAMPKIN, BEATRICE
LAMPKIN, BEATRICE
UMPKIN, BEATRICE
LAMPKIN, BEATRICE
LAMPKIN, BEATRICE C
LANDOWNE, DAVID
LANDSBERG, LEWIS
LANE, LOIS K
LANG, L GEORGE
LANGE, ROBERT D
LANGE, YVONNE
LANGER, GLENN A
LANGER, GLENN A
LANGER, GLENN A
LANGER, GLENN A
LANGER, GLENN A
LANGFORD, HERBERT G
LANGNER, RONALD 0
LARAGH, JOHN H
LARAGH, JOHN H
LARAGH, JOHN H
LARAGH, JOHN H
LASKER, SIGMUND E
LASKOWSKI, MICHAEL,
LATIMER, PAUL H
LAUBACH, CHARLES A
LAUBACH, CHARLES A,
LAUER, RONALD M
LAUER, RONALD M
LAUF, P K
LAURSEN, RICHARD A
LAW, JOHN H
LAWLER, JAMES E
LAWSON, WILLIAM B
LAWTON, WILLIAM
LAYMAN, DON L
LAYTON, WILLIAM M,
LAZAROW, PAUL B
LEAF, ALEXANDER
LEAF, ALEXANDER
LEAF, ALEXANDER
ROIHLI 787904
R01HL1642I08
P0IHL1820804
R23HL21332 02
R01HL1608705
N01HV3293109
N01HV62900 00
POIHL 18208 04 0005
P50HL19190 02 0003
POIHL 10436 13 0006
R01HL2 1996-01
P01HL03 174-23 0009
R01HL23593-01
P01HL08805 15 0039
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P0IHL08899-14 0078
P01HL08899-14 0079
P01HL08899-14 0080
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P60HL15996-06 0003
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P60HL15996-06 0009
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POIHLI 1351-12 0009
P01HL11351-12 0010
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R01HL18891-02
R01HL15478-05
P50HL18323-04
P50tt).18323-04 0011
P50HL18323-04 0012
P50HL18323-04 0034
R01HL18068-02
R01HL15892-05
R01HL18256-01
N01HV82903-02
R01HL11372-08
P50HL14230-07 0088
R01HL20124-02
P01HL12157-11 0033
R01HL15535-06
P50HL1 5062-07 0008
R01HL19680-01
R01HL15887-05
P01HL14388-07 0224
R01HL21303-02
R01HL19430-03
R01HL20909-02
P01HL06664-17
P01HL06664-17 0042
P01HL06664-17 0043
AlPHABETICAl USTING OF INVESTIGATORS
'<■■.
¥
LEAK, LEE V
LEAMAN, DAVID M
LEAVIS, PAUL C
LEBOWITZ, MICHAEL D
LEBOWITZ, MICHAEL D
LEDERMAN, DAVID
LEE-HUANG, SYLVIA
LEE, CHIN 0
LEE, GEORGE C
LEE, JOHN C
LEE, IWANG S
LEE, KW/ANG S
LEE, KW/ANG S
LEE, KYU T
LEE, KYU T
LEE, MARY M L
LEE, PING
LEE, TED C K
LEE, WILLIAM W
LEEDS, SANFORD E
LEES, ROBERT S
LEFKOWITZ, ROBERT J
LEFKOW/ITZ, ROBERT J
LEHAN, PATRICK H
LEHNER, NOEL D M
LEHNER, NOEL D M
LEHRER, SAMUEL B
LEHRER, SHERWIN S
LEINBACH, ROBERT C
LEIN8ACH, ROBERT C
LEITCH, CYNTHIA J
LEITH, DAVID E
LEITH, DAVID E
LEMANSKI, LARRY F
LEPESCHKIN, EUGENE
LEQUIRE, VIRGIL S
LEQUIRE, VIRGIL S
LERNER, ROBERT G
LESCH, MICHAEL
LESLIE, CRYSTAL A
LEUNG, JOSEPH
LEV, MAURICE
LEVERE, RICHARD D
LEVEY, GERALD S
LEVIN, D C
LEVIN, DAVID C
LEVIN, JACK
LEVIN, JEROME A
LEVINE, FREDERICK D
LEVINE, FREDERICK H
LEVINE, HERBERT J
LEVINE, PETER H
LEVINE, RHEA J C
LEVINE, S
LEVINSKY, NORMAN G
LEVINSKY, NORMAN G
LEVINSON, DENNIS J
LEVITSKY, SIDNEY
LEVITSKY, SIDNEY
LEVin, MORTON
LEVin, MORTON
LEVITZKY, MICHAEL G
LEVY, MAHHEW N
LEVY, MAHHEV^ N
LEW, GLORIA M
LEWIS, JESSICA H
LEWIS, JON C
LEWIS, JON C
LEWIS, ROBERT A
LEWIS, ROBERT M
LEWIS, STEVEN M
LIANG, CHANG-SENG
LICHSTEIN, EDGAR
LICHTENSTEIN, LAWRE
LICHTENSTEIN, LAWRE
LICHTMAN, MARSHALL
LICHTMAN, MARSHALL
LIEBERMAN, JACK
LIEBERMAN, M
LIEBERMAN, M
LIEDTKE, A JAMES
LIEN, DONNA M
LIENER, IRVIN E
LILLEHEI, RICHARD C
LIMAS, CONSTANTINOS
LIMBIRD, LEE E
LIN, HSIU-SAN
LIN, SHU-REN
LINDGREN, FRANK T
LINDGREN, FRANK T
LINDLEY, BARRY D
LIPPMANN, MORTON
594
R01HL13901-08
R01HL17954-03
R01HL20464-01
P50HL14136-07 0016
P50HL14 136-07 9001
N01HV72937-00
R01HL21683-02
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P50HL1 5092-07 0011
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P50HL1 7665-04 0021
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R01HL07139-17
N01HB530I9-06
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P01HL08805-15 0047
P50HL18318-03 0013
R01HL22172-01
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LIPSCOMB, KIRK
LISTOWSKY, IRVING
LITT, MITCHELL
Lin, MITCHELL
LITTEN, RAYE Z, III
LimE, ALICK
LimE, WILLIAM
LITWAK, ROBERT S
LIU, MAW-SHUNG
LLOYD, THOMAS C, JR
LOBERG, MICHAEL D
LODA, FRANK A
LOGERFO, FRANK W
LOHMEIER, THOMAS E
LOHMEIER, THOMAS E
LOKE, JACOB S
LOKHANDWALA, MUSTAF
LOMBARD, JULIAN H
LONG, JOHN M
LONGHURST, JOHN C
LONGINI, RICHARD L
LONGMORE, WILLIAM J
LONGMUIR, IAN S
LONGNECKER, DAVID E
LORAND, LASZLO
LORAND, LASZLO
LORIA, ROGER M
LORING, STEPHEN H
LOSKUTOFF, DAVID J
LOUD, ALDEN V
LOURENCO, RUY V
LOVE, SAMUEL H
LOW, ROBERT B
LOW, ROBERT B
LOWENHAUPT, ROSALIN
LOWENSTEIN, EDWARD
LOWN, BERNARD
LOWN, BERNARD
LUCCHESI, BENEDICT
LUCCHESI, BENEDICT
LUCHTEL, DANIEL L
LUDBROOK, PHILIP A
LUETSCHER, JOHN A,
LUETSCHER, JOHN A,
LUMB, ROGER H
LUMB, WILLIAM V
LUMRY, RUFUS
LUSHER, JEANNE M
LUX, ROBERT L
LYMAN, DONALD J
LYNN, W S
LYNN, WILLIAM S
LYNN, WILLIAM S
LYONS, HAROLD A
MACKLEN, P T
MACLEAN, WILLIAM A
MACY, JOSIAH, JR
MACY, JOSIAH, JR
MACY, JOSIAH, JR
MADERAZO, EUFRONIO
MAGNO, MICHAEL
MAGNUSSON, STAFFAN
MAISELS, M JEFFREY
MAISELS, M JEFFREY
MAJERUS, PHILIP W
MAJERUS, PHILIP W
MAJERUS, PHILIP W
MAJNO, GUIDO
MAKARSKI, JOSEPH S
MALIK, ASRAR B
MALIK, KAFAIT U
MALIK, KAFAIT U
MALIK, MAZHAR N
MALINOW, MANUEL R
MALMUO, LEON S
MALONEY, JAMES V, J
MALONEY, JAMES V, J
MALONEY, JAMES V, J
MALVIN, RICHARD L
MAMMEN, EBERHARD F
MANASEK, FRANCIS J
MANDEL, FREDERIC
MANDEL, RICHARD
MANDEL, WILLIAM J
MANDL, INES
MANDL, INES
MANDL, INES
MANDL, INES
MANN, KENNETH G
MANN, KENNETH G
MANNING, JAMES M
MANNING, JOHN W
P50H LI 7669-04 0008
R01HL11511-10
R01HL14271-07
R01HL23267-01
R01HL22845-01
N01HV22917-11
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P01HL16387-04 0006
R01HL236 18-01
R01HL15694-06
R01HL18744-03
P50HL19171-02 0005
R01HL21796-01
P01HL11678-11 0066
POIHLI 1678-11 0067
R23HL22895-01
R01HL22868-01
R23HL22972-01
P01HL15265-05 0004
R23HL22669-01
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R01HL13405-09
R01HL16828-04
R01HL17091-05
R01HL02212-23
R01HL16346-09
R01HL18152-03
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P01HL16769-05 0011
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R01HL19806-03
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POIH LI 5832-06 0009
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R01HL18819-07
R01HL16648-16
MANNING, R DAVIS, J
MANNING, R DAVIS, J
MANSFIELD, PETER B
MANSOUR, TAG E
MANTLE, JOHN A
MARCHESI, SALLY L
MARCUS, AARON J
MARCUS, MELVIN L
MARCUS, MELVIN L
MARCUS, MELVIN L
MARCUS, MELVIN L
MARDER, VICTOR J
MARDER, VICTOR J
MAREN, THOMAS H
MARGOLIASH, EMANUEL
MARGOLIES, MICHAEL
MARGOLIS, SIMEON
MARGOLIS, SIMEON
MARGOLIUS, HARRY S
MARIN, MAnHEW G
MARINEni, GUIDO V
MARK, ALLYN L
MARK, ALLYN L
MARK, ALLYN L
MARK, ALLYN L
MARK, ALLYN L
MARKHAM, JOANNE
MARKHAM, JOANNE
MARKLAND, FRANCIS S
MARKS, BERNARD H
MARKWALD, ROGER R
MARMORSTON, JESSIE
MAROKO, PETER R
MAROKO, PETER R
MARSH, JULIAN B
MARSH, JULIAN B
MARSH, JULIAN B
MARSH, JULIAN B
MARSHALL, BRYAN E
MARSHALL, BRYAN E
MARSHALL, BRYAN E
MARSHALL, BRYAN E
MARSHALL, GARLAND R
MARSHALL, GARLAND R
MARSHALL, GARLAND R
MARSHALL, HIRAM W
MARTIN, ANNE F
MARTIN, ANNE F
MARTIN, CARROLL J
MARTIN, PAUL J
MARTIN, ROY W
MARTINEZ-CARRION, M
MARTINEZ, J RICARDO
MARTINEZ, JOSE
MARX, JAMES J
MASHBURN, THOMPSON
MASON, DEAN T
MASON, JAY W
MASON, JAY W
MASON, JAY W
MASON, REGINALD G,
MASON, REGINALD G,
MASON, ROBERT J
MASORO, EDWARD J
MASOUREDIS, SERAFEI
MASSARO, DONALD J
MASSARO, DONALD J
MASSARO, GLORIA D
MASTERS, BETTIE S
MATES, ROBERT E
MATES, ROBERT E
MATHE, ALEKSANDER A
MATHE, ALEKSANDER A
MATHEWS, JOHN D
MATHEWS, LOUIS B
MATHIAS. MELVIN M
MATLIB, M ABDUL
MATSCHINER, JOHN T
MAnHEWS, LEROY W
MAUGHAN, DAVID W
MAURICE, GORDON L
MAXWELL, MORTON H
MAXWELL, MORTON H
MAYER, STEVEN E
MAYER, STEVEN E
MAYER, STEVEN E
MAYERLE, JOAN A
MAYNE, RICHARD
MAYROVITZ, HARVEY N
MAZZARA, JAMES T
MAZZONE, ROBERT W
MC ALISTER, ALFRED
P01HL11678-11 0001
POIHLI 1678-11 0059
N01HV12060-18
R01HL17976-I8
P50HL17667-04 0018
R01HL20140-02
P50HL1 8828-03 0008
P01HL14388-07 0216
P01HL14388-07 0217
P01HL14388-07 0219
R01HL20827-02
P50HL14217-08 0049
R01HL21379-01
R01HL22258-01
R01HL11119-17
P01HL19259-03 0001
R01HL15930-06
R01HL19095-03
ROIHL 17 705-04
R01HL2 13 14-02
R01HL02063-23
P01HL14388-07 0184
P01HL14388-07 0186
P01HL14388-07 0210
P01HL14388-07 0220
P01HL14388-07 0230
P50HL1 7646-04 0002
P50HL1 7646-04 0006
R01HL22875-01
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N01HV42931-07
P50HL1 7665-04 0008
R01HL20 199-02
R01HL19168-03
P01HL22633-01
P01HL22633-01 0001
P01HL22633-01 9002
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R01HL16916-04 0001
R01HL16916-04 0002
R01HL16916-04 0011
R01HL14509-07
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N01HV72944-02
P01HL04664-18 0013
P01HL22619-01 0007
R01HL22651-01
R01HL22313-01
R01HL22484-01
R01HL14645-07
R01HL22265-02
P50HL19160-02 0001
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P01HL13108-09 0018
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P01HL15194-07 9002
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R01HL15677-06
P01HL19717-02 0037
R01HL19984-02
N01HV72953-04
R01HL18239-03
P01HL22619-01 0010
R01HL19322-03
R0IHL13885-08
R01HL21312-01
N01HV72965-02
R01HL22069-02
N01HV12436-15
P01HL12373-10 0012
P01HL12373-10 0018
P50HL17682-04 0020
P01HL06285-18 0205
R01HL21665-01
R01HL22738-01
R01HL18984-01
R23HL21943-01
R23HL22947-01
MC CAA. ROBERT E
MC CALL. DAVID
MC CALLISTER, LAWRE
MC CALLUM. DAVID B
MC CARL, RICHARD L
MC CARTNEY. MICHAEL
MC CARn. MACLYN
MC CONN. RITA
MC COY. LOWELL E
MC CULLOUGH. JEFFRE
MC CURDY. PAUL R
MC CUSKEY. ROBERT S
MC DONAGH. JAN M
MC DONAGH. RICHARD
MC DONALD. TED P
MC FADDEN, EOVKARD R
MC GIFF. JOHN C
MC GILL, HENRY C
MC GILL. HENRY C. J
MC GOVI/AN. ELEANOR B
MC HENRY.
LAWRENCEC
MC INTIRE. LARRY V
MC INTIRE. LARRY V
MC KEE. PATRICK A
MC LAUGHLIN. ROBERT
MC LENDON. GEORGE L
MC MAHON. THOMAS A
MC MILLAN. C W
MC MILLIN. CARL R
MC MURRY. JOHN E
MC NAMARA. J JUDSON
MC NAMARA, JOSEPH J
MCCAA, ROBERT E
MCCAA, ROBERT E
MCCALL, CHARLES E
MCCLUSKEY. ROBERT
MCDANIEL. HUEY G
MCDANIEL, HUEY G
MCDONAGH. RICHARD P
MCDONALD. DONALD M
MCDONALD. DONALD M
MCDONALD, DONALD M
MCFADDEN, EDWARD R
MCFADOEN, REGIS
MCGILL, HENRY C, JR
MCGILL. HENRY C, JR
MCHENRY. PAUL L
MCINTOSH, HENRY D
MCINTOSH, HENRY D
MCMAHAN, C ALEX
MCMAHON, THOMAS A
MCMANUS, T J
MCMULLEN. JOHN
MCMURTRY. IVAN F
MEAD, JERE
MEAD. JERE
MEANS, ANTHONY R
MECHAM. ROBERT P
MEERBAUM. SAMUEL
MEEZAN, ELIAS
MEHENDALE, HARIHARA
MEIER, GEORGE D
MEIER, PAUL
MEIER, ROBERT C
MEINERT, CURTIS L
MEISELMAN, HERBERT
MEISELMAN, HERBERT
MEISNER. HERMAN M
MEL6IN, JULIUS
MELBY, JAMES C
MELBY, JAMES C
MELLINS, ROBERT B
MELMON, KENNETH L
MELNICK, JOSEPH L
MEMMI, CARLOS
MENDELSON, ROBERT A
MENOICINO, JOSEPH F
MENG, H C
MENKES, HAROLD A
MENTZER, WILLIAM C
MENTZER, WILLIAM C
MENTZER, WILLIAM C,
MENZ, LEO
MERGNER, WOLFGANG J
MERIMEE. THOMAS J
MERIN. ROBERT G
MERRILL, EDWARD W
MERSKEY, CLARENCE
MERSKEY, CLARENCE
METCALF, JOHN F
MEYER. EDWARD C
R01HL09921 13
R01HL2256801
R01HL1863I03
N01HV7298702
ROIHLIOOIS'U
R01HL2251701
R01HL03919-20
R01HL1747904
R01HL20317 02
N01HB6297205
R01HLI4131 18
R01HL2360401
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P50HL18318-03 0004
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MEYER. WALTER J, II
MICHAEL, ALFRED F
MICHAELI, DOV
MICHAELI, DOV
MICHEUKIS. ANDREW
MICHELAKIS, ANDREW
MIKLICH. DONALD R
MILHORN. HOWARD T
MILLAR. KAY
MILLER, EDWARD
MILLER, J N
MILLER. JAMES G
MILLER, MARILYN E
MILLER. MICHAEL E
MILLER. NEAL E
MILLER. NORMAN B
MILLER. R DREW
MILLER. RICHARD R
MILLER. RUSSELL L
MILLER. THOMAS B, J
MILLS, DAVID C B
MILNER, PAUL F
MILNER, PAUL F
MILNOR, WILLIAM R
MINES, ALLAN H
MINH, VU-DINH
MINICK, C RICHARD
MINICK, C RICHARD
MINICK, C RICHARD
MINICK, CHARLES R
MINICK, RICHARD C
MINOR, RONALD R
MIRSKY, ISRAEL
MIRSKY, ISREAL
MIRVIS, DAVID M
MITCHELL. DANIEL S
MITCHELL, JERE H
MITCHELL, JERE H
MITCHELL, RICHARD R
MITCHELL, ROBERT A
MIHMAN, CHARLES
MIHMAN, CHARLES
MITZNER. WAYNE
MIZUKAMI, HIROSHI
MOCKROS, LYLE F
MOE, GORDON K
MOFFAT, JOHN K
MOHN, JAMES F
MOHRMAN, DAVID E
MOISE, JOHN C
MOLTENI, AGOSTINO
MOMMAERTS, WILFRIED
MONTGOMERY, ROBERT
MOOR-JANKOWSKU, JAN
MOORE, E NEIL
MOORE, E NEIL
MOORE, RICHARD B
MOORE, VERNON L
MOORE, VERNON L
MOORE, VERNON L
MOORE, WESLEY S
MORAO, MARTIN
MORAD, MARTIN
MORALES, MANUEL F
MORAN, NEIL C
MORETTI, RICHARD L
MOREni, RICHARD L
MORETTI, RICHARD L
MORGAN. HOWARD E
MORGAN, HOWARD E
MORGAN, HOWARD E
MORIN, RICHARD A
MORIN, ROBERT J
MORISHIGE, WALTER K
MORITZ, WILLIAM E
MORITZ, WILLIAM E
MORITZ, WILLIAM E
MORITZ, WILLIAM E
MORITZ, WILLIAM E
MORKIN, EUGENE
MORKIN, EUGENE
MORKIN, EUGENE
MORRIS, ALAN H
MORRIS, HELEN G
MORRIS, MARIANA
MORRIS, THOMAS W
MORRISEH, JOEL D
MORRISEn, JOEL D
MORRISON, DAVID C
MORSE, JANE H
MORTENSEN, J D
MORTON, NEWTON E
i95
R01HL2020101
P01HL06314 17 0062
R01HL1752503
N01HV4298405
R01HL180I904
R01HL1802703
R01HL2131802
P01HL11678 11 0009
POIHL 13480-09 0026
P01HL11310 12 0106
P01HL07896 15 0045
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R01HL2000203
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P01HL11351-12 0004
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N01HB4297112
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R01HL23071-01
P01HL15265-05 0003
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ALPHABETICAL LISTING Of INVESTIGATORS
MOSBACH, ERWIN H
MOSCHOS, CHRISTOS B
MOSCOWITZ, ALBERT
MOSER, KENNETH M
MOSESSON. MICHAEL W
MOSESSON, MICHAEL W
MOSESSON, MICHAEL W
MOSHER. DEANE F. JR
MOSKOWIIZ. MITCHELL
MOSKOWITZ, MITCHELL
MOSKOWITZ, MITCHELL
MOSKOWITZ, MITCHELL
MOSKOWITZ, MITCHELL
MOSKOWITZ, MITCHELL
MOSKOWITZ, MITCHELL
MOSKOWITZ, MITCHELL
MOSS, ARTHUR J
MOSS, ARTHUR J
MOSS, NED
MOTOYAMA, ETSURO K
MOn, GLEN E
MOn, GLEN E
MOn, GLEN E
MUELLER, GILTRUD
MUESING, RICHARD A
MUIRHEAD, ERNEST E
MULLEREBERHARD. HA
MULLER-EBERHARD. HA
MULLINS. CHARLES B
MULROW, PATRICK J
MULROW, PATRICK J
MUNDTH, ELDRED D
MUNNS, THEODORE W
MURAD, FERID
MURPHY M J JR
MURPHY,
MURPHY, ALEXANDER J
MURPHY, GEORGE E
MURPHY, SCOn
MURRAY, JOHN F
MURRAY, ROBERT F, J
MUSE, KENNETH E
MUSTAFA, SYED J
MYERBURG, ROBERT J
MYERBURG, ROBERT J
MYRVIK, QUENTIN N
MYRVIK, QUENTIN N
MYRVIK, QUENTIN N
MYRVIK, QUENTIN N
NACHMAN, RALPH L
NACHMAN, RALPH L
NACHMIAS, VIVIANNE
NADAS, ALEXANDER S
NADAS, ALEXANDER S
NADAS, ALEXANDER S
NADEL, ALFRED J
NADEL. ETHAN R
NADEL, JAY A
NADEL, JAY A
NADEL, JAY A
NADEL, JAY A
NADEL, JAY A
NADEL, JAY A
NADEL, JAY A
NAGEL, RONALD L
NAGEL, RONALD L
NAGEL, RONALD L
NAGEL, RONALD L
NAGEL, RONALD L
NAGEL. RONALD L
NAIR. PANKAJAM
NAITO, H K
NAKAMURA, ROBERT M
NAKEFF, ALEXANDER
NASJLEni, ALBERTO
NATHAN, DAVID
NATHAN, DAVID G
NATHAN, MARC A
NATHAN, MARC A
NATHAN, RICHARD D
NAnA, CLAYTON L
NATTIE, EUGENE E
NAVAR, LUIS G
NEEOLEMAN, PHILIP
NEEDLEMAN, PHILIP
NEEOLEMAN, PHILIP
NEEDLEMAN, PHILIP
NEELY, JAMES R
NEELY, JAMES R
NEELY, JAMES R
NEILL, CATHERINE A
NELLIS, STEPHEN H
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ALPHABETICAL LISTING OF INVESTIGATORS
I
NELSESTUEN, GARY L
NELSON, ERWNO R
NELSON, NICHOLAS M
NELSON, NICHOLAS M
NELSON, THOMAS E
NEMECEK. GEORGINA M
NEMERSON, YALE R
NEREM, ROBERT M
NESS, GENE C
NEURATH, A R
NEW, MARIA I
NEW, MARIA I
NEWBALL, HAROLD H
NEWBALL, HAROLD H
NEWELL, JONATHAN C
NEWMAN, JACK
NEWMAN, WALTER H
NIARCHOS, ANDREAS D
NICHOLS, ALEX V
NICHOLS, C J
NICHOLS, CHARLES W
NICHOLS, CHARLES W
NICHOLS, CHARLES W
NICHOLS, WILLIAM K
NICHOLSON, BRUCE L
NIEDERMIER, WILLIAM
NIEHAUS, WALTER G,
NIES, ALAN S
NIEWIAROWSKI, STEFA
NIEWIAROWSKI, STEFA
NISHIOA, TOSHIRO
NOBLE, ROBERT W
NOUN, STANTON P
NOON, GEORGE P
NOORDERGRAAF,
ABRAH
NORIN, ALLEN J
NORIN, ALLEN J
NORMAN, JOHN C
NORMAN, JOHN C
NORMAN, PHILIP S
NORMAN, ROGER A, JR
NORMAN, ROGER A, JR
NORTHWAY, WILLIAM H
NORTON, TED R
NORWOOD, WILLIAM I
NOSE, YUKIHIKO
NOSE, YUKIHIKO
NOSSEL, HYMIE
NOSSEL, HYMIE L
NOSSEL, HYMIE L
NOSSEL, HYMIE L
NOSSEL, HYMIE L
NOSSEL, HYMIE L
NOWYGROD, ROMAN
NUDELMAN, SOL
NUTE, PETER E
NYILAS, EMERY
NYILAS, EMERY
O'BRIEN, JOHN F
O'DELL, BOYD L
O'SULLIVAN, JOHN B
OALMANN, MARGARET C
GATES, JOHN A
OBANNON, WILLIAM
OBERMAN, ALBERT
08ERMAN, ALBERT
OBERMAN, ALBERT
OBRIST, PAUL A
ODESSEY, RICHARD
OEGEMA, THEODORE R
OGAWA, MAKIO
OGRA, PEARAY L
OHNISHI, TSUYOSHI
OKAMOTO, KOZO
OKEN, DONALD E
OKITA, GEORGE T
OLDFIELD, ERIC
OLDHAM, H NEWLANO
OLINGER, CHARLES P
OLIVER, CHARLES G
OLIVER, G CHARLES
OLIVER, G CHARLES
OLIVER, G CHARLES
OLSON, JOHN S
OLSON, MERLE S
OLSSON, RAY A
OLSZOWKA, ALBERT J
OMACHI, AKIRA
ONCLEY, J WWRENCE
ONG, ENG B
ONG, ENG 8
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P50HL14136-07 9004
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POIHLI 5596-05 0019
ONTKO, JOSEPH A
OPDYKE, DAVID F
OPPENHEIM, JOEL D
OREM, JOHN M
ORENSTEIN, DAVID M
ORITZ DE MONTELLANO
ORKIN, STUART H
ORLOWSKI, MARIAN
ORTH, DAVID N
ORTH, DAVID N
OSTFELD, ADRIAN M
OSTRANDER, LEE E
OSTRANDER, LEON D,
OSTRO, MARC J
OTIS, ARTHUR B
OU, LO-CHANG
OVERBECK, HENRY W
OVERBECK, HENRY W
OVERTURE, GARY D
OVERTURF, MERRILL L
OVin, THERON W
OWEN, CHARLES A
OWEN, PAHY J
OWEN, WHYTE G
PACE, JOHN B
PACK, A
PAFFENBARGER, RALPH
PAGANELLI, CHARLES
PAGE, ERNEST
PAGE, ERNEST
PAGE, ERNEST
PAGE, ERNEST
PAGE, ERNEST
PAI, A L
PALADE, GEORGE E
PALEK, JIRI
PALMER, ROGER F
PALUMBO, PASQUALE J
PALUMBO, PASQUALE J
PANG, DAVID C
PANGANELLI, C V
PAPKA, RAYMOND E
PAPPANO, ACHILLES J
PARK, BYUNG H
PARK, SUNG S
PARKER, FRANK
PARKER, JAMES C
PARKEY, ROBERT W
PARKHURST, LAWRENCE
PARMLEY, WILLIAM W
PARMLEY, WILLIAM W
PARMLEY, WILLIAM W
PARMLEY, WILLIAM W
PARMLEY, WILLIAM W
PARMLEY, WILLIAM W
PARODI, EDUARDO N
PARSHLEY, MARY S
PARSONNET, VICTOR
PARSONS, RODNEY L
PAnERSON, DONALD F
PATTERSON, RANDOLPH
PAHERSON, ROY
PATZ, ARNALL
PAUL, RICHARD J
PAULIN, SVEN
PAULIN, SVEN J
PAVLIN, DOROTHY J
PAWLOWSKI, PHILIP J
PEACH, MICHAEL J
PEARSON, HOWARD A
PEASE, DANIEL C
PECHET, LIBERTO
PEDRINI, VITTORIO A
PEGRAM, BARBARA L
PEISACH, JACK
PEISACH, JACK
PEMRICK, SUZANNE M
PENICK, GEORGE D
PENICK, GEORGE D
PENNEY, DAVID G
PENNINGTON, G
PENNINGTON, G
PENNINGTON, G
PENNINGTON, G
PENNINGTON, G
PENNINGTON, G
PENNINGTON, G
PENNINGTON, JAMES E
PEPE, FRANK A
PEPE, FRANK A
PERLMAN, ROBERT L
PERMUTT, SOLBERT
596
R01HL13302-09
R01HL18868-03
R23HL21328-02
R01HL21257-02
R23HL21954-01
R01HL15476-05
R23HL2 1428-02
R01HL21 105-02
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R01HL2 1159-02
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P01HL08682-15 0038
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PERMUTT, SOLBERT
PERMUTT, SOLBERT
PERNOW, BENGT B
PERSIDSKY, MAXIM D
PERSON, RONALD
PESKIN, CHARLES S
PETERS, JEFFREY L
PETERS, RICHARD M
PETERS, ROBERT W
PETERS, THEODORE, J
PETERSDORF, ROBERT
PETERSEN, ROBERT 0
PETERSON, KIRK L
PETERSON, KIRK L
PETERSON, KIRK L
PETERSON, KIRK L
PETTY, THOMAS L
PETTY, THOMAS L
PETZ, LAWRENCE D
PHIBBS, RODERIC
PHIBBS, RODERIC H
PHILIP, R B
PHILLIPS, DAVID R
PHILLIPS, DAVID R
PHILLIPS, GERALD B
PHILLIPS, JERRY C
PHILLIPS, JERRY L
PHILLIPS, M IAN
PHILLIPS, MICHAEL C
PHILLIPS, ROLAND L
PHILLIPS, STEVEN J
PICCIANO, PAUL T
PICK, RUTH
PICKARD, WILLIAM F
PICKEL, VIRGINIA M
PIEPER, HEINZ P
PIEPER, HEINZ P
PIERCE, JOHN A
PIERCE, WILLIAM S
PIERCE, WILLIAM S
PIERSON, RICHARD N,
PIETRA, GUISEPPE G
PIETRA, GUISEPPE G
PIETRA, GUISEPPE G
PIETRA, GUISEPPE G
PIETRAFinA, J
PILKINGTON, THEO C
PIMMEL, RUSSELL L
PINCKARD, ROBERT N
PINCKARD, ROBERT N
PINDYCK, JOHANNA
PINKUS, GERALDINE
PINNELL, SHELDON R
PINTER, GABRIEL G
PINTO, JOHN G
PIOMELLI, SERGIO
PIPBERGER, HUBERT V
PIPBERGER, HUBERT V
PIRANI, CONRAD L
PIHMAN, R0L;\ND N
Pins, BARRY J
Pins, BARRY J R
PLACHY, WILLIAM Z
PLONSEY, ROBERT
PLONSEY, ROBERT
PLOW, EDWARD F
POGO, A OSCAR
POGO, A OSCAR
POHOST, GERALD M
POHOST, GERALD M
POIRIER, VICTOR C
POISNER, ALAN M
POLET, HERMAN
POLGAR, PETER
POLLACK, GERALD H
POLLACK, GERALD H
POLLEY, MARGARET J
POLMAR, STEPHEN H
POOLE, KENNETH W
POOLE, KENNETH W
POPJAK, GEORGE J
POPOVIC, VOJIN P
POPP, RAYMOND A
POPP, RICHARD L
PORTER, JOHN W
PORTER. NED A
PORTER, NED A
PORTMAN, OSCAR W
PORTNER, PEER M
PORTNER, PEER M
PORTNER, PEER M
PORTOGHESE, PHILIP
P01HL1034213 0008
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P01HL20994-02 9003
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POIHLI 1307-12 9002
R01HL19118-03
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PORUSH. JEROME G
POST, ROBERT L
POTH. P W
POnER. lAMES D
POnER. LINCOLN T
POWARS, DARLEEN R
POWARS, DARLEEN R
POWELL, WILLIAM J,
POWELL, WM JOHN
POWER, GORDON G
POWERS, JAMES C
POWERS, JAMES C
POWERS, MARJORIE J
POWNALL, HENRY J
POWNALL, HENRY J
PRANCAN, ARTHUR V
PRASAD. ANANDA S
PREDECKI, PAUL K
PRESSMAN. BERTON C
PRESSMAN, BERTON C
PREWin, RUSSELL L,
PRICE. HENRY L
PRICE. HENRY L
PRICE, JOEL M
PRICE, KENNETH F
PRICE. THOMAS H
PRIMIANO. F P
PRINEAS. RONALD J
PRINTZ. MORTON P
PRINTZ. MORTON P
PRINTZ, MORTON P
PRIOLA, DONALD V
PRITCHETT. EDWARD L
PRIVETT, ORVILLE S
PRIVETT, ORVILLE S
PROCKOP, LEON 0
PROCKOP, LEON D
PROCTOR, DONALD F
PROCTOR, DONALD F
PROPPE, DUANE W
PROPPE, DUANE W
PROUGH, RUSSELL A
PROUT, THADDEUS E
PRUEin. JOHN L
PRUEITT, JOHN L
PRYOR, T ALLAN
PRYOR, WILLIAM A
PUGLIA. CHARLES D
PUSZKIN, ELENA
PUSZKIN, ELENA G
PUSZKIN, SAUL
QUARFORDT, STEVEN H
QUINN, JOHN A
QUINN, JOHN A
QUINN, JOHN A
QUINN, JOHN A
QUINN, JOHN A
QUINN, JOHN A
QUINN, JOHN A
RAB6, MAURICE F
RAB6, MAURICE F
RABELLINO, ENRIQUE
RABINOWITZ, MURRAY
RABINOWITZ, MURRAY
RABINOWITZ, MURRAY
RABNER, BUDDY D
RACKLEY, CHARLES E
RACKLEY, CHARLES E
RACKLEY, CHARLES E
RADCLIFFE, ROBERT
RADCLIFFE, ROBERT D
RADER, ROLAND D
RADHAKRISHNAMURTHY,
RADHAKRISHNAMURTHY,
RADVANY, PAULO
RAHIMTOOLA, SHAHBUD
RAHWAN, RALF G
RAKITZIS, E T
RAMON, FIDEL
RAMSAY, DAVID J
RAMWELL, PETER W
RAMWELL, PETER W
RAND, PETER W
RANDALL, DAVID C
RANDALL, OTELIO S
RANDALL, WALTER C
RANDALL, WALTER C
RANDALL, WALTER C
RANDALL, WALTER C
RANDALL, WALTER C
RANHEIM, PHILLIP J
RANKIN, JOHN H
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ROIHL 186 7904
R01HL2253001
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RANNELS, D EUGENE
RANNELS, D EUGENE,
RAPAPORT. ELLIOT
RAPAPORT, ELLIOT
RAPAPORT, SAMUEL I
RAPP, JOHN P
RASHKIND, WILLIAM J
RATNOFF, OSCAR D
RATZAN, KENNETH R
RAU, ERIC E
RAUTAHARJU, P M
REAVEN, GERALD M
REAVEN, GERALD M
REBA, RICHARD C
RECTOR, FLOYD C
RECTOR, FLOYD C
RECTOR, FLOYD C
RECTOR, FLOYD C
REDDY, WILLIAM J
REDOY, YERRADHODDI
REDMAN, COLVIN M
REEMTSMA, KEITH
REEVE, E BASIL
REEVES, JOHN T
REEVES, JOHN T
REEVES, JOHN T
REEVES, JOHN T
REEVES. JOHN T
REEVES. JOHN T
REEVES, ROBERT B
REGAN, TIMOTHY J
REGNIER, FRED E
REHDER, KAI
REICHENBACH, DENNIS
REICHENBACH, DENNIS
REICHLIN, MORRIS
REID, JOHN M
REID, JOHN M
REID, LYNNE M
REID, LYNNE M
REID, LYNNE M
REID, LYNNE M
REID, LYNNE M
REID, LYNNE M
REID, LYNNE M
REIF, JOHN S
REIFFEL, J A
REINECK, HENRY J
REINER, JOHN M
REIS, DONALD J
REIS, DONALD J
REIS, DONALD J
REIS, DONALD J
REIS. DONALD J
REIVICH, M
REIVICH, M
REMMERS, JOHN E
RENKIN, EUGENE M
RENKIN, EUGENE M
RENNE, CHARLES M
RENNERT, OWEN M
RENNICK, BARBARA R
RENNIE, DONALD W
RENNIE, DONALD W
RESNEKOV, LEON
REVESZ, GEORGE
REYNOLDS, EDWARD S
REYNOLDS, HERBERT Y
REYNOLDS, JACQUELIN
REYNOLDS, ROLLAND C
RHEE, HEE M
RHO, JOON H
RHOADES, RODNEY A
RHYNE, A LEONARD
RICCI, DONALD R
RICCI, DONALD R
RICCI, DONALD R
RICE, DAVID A
RICH, ALEXANDER
RICHARDS, E GLEN
RICHARDS, JOHN H
RICHARDS, N MARK
RICHARDSON, DAVID D
RICHARDSON, PETER D
RICHARDSON, PETER D
RICHERSON, HAL B
RICHERSON, HAL B
RICHMOND, VIRGINIA
RIESKE, JOHN S
RIFKIN, DANIEL B
RIGAHO, HENRIQUE
RIM, KWAN
5«7
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ALPHABETICAL LISTING OF INVESTIGATORS
RIMM, ALFRED A
RIMM, ALFRED A
RINARD, GILBERT A
RIORDAN, JAMES F
RIOS, JORGE
RinENHOUSE SIMMONS
RinER, A B
ROBBINS, KENNETH C
ROBERTS, HAROLD R
ROBERTS, HAROLD R
ROBERTS, JAY
ROBERTS, LOU A
ROBERTS, ROBERT
ROBERTS, ROBERT
ROBERTS, RONALD C
ROBERTSON, ABEL L
ROBIN, EUGENE D
ROBINSON, NORMAN E
ROBINSON, RICHARD
ROBSON, RICHARD M
ROCHESTER, DUDLEY F
ROCHESTER, DUDLEY F
ROCHESTER, DUDLEY F
ROCKEY, JOHN H
RODARATE, JOSEPH R
RODEN, LENNART
RODEWALO, RICHARD D
RODGERS, JOHN B, JR
RODMAN, THEODORE
RODVIEN, ROBERT
RODWELL, VICTOR W
ROE, CHARLES R
ROE, CHARLES R
ROESKE, WILLIAM R
ROESKE, WILLIAM R
ROGERS, KENNETH
ROGERS, MICHAEL E
ROGERS, WALTER R
ROGERS, WALTER R
ROHEIM, PAUL S
ROHRBACH, MICHAEL S
ROMAN, STANFORD A,
ROMAN, STANFORD A,
ROMAN, STANFORD A,
ROMERO, JUAN C
ROOS, ALBERT
ROSATi, ROBERT A
ROSATI, ROBERT A
ROSE, GEORGE G
ROSELLI, ROBERT J
ROSEN, JONATHAN J
ROSEN, KENNETH M
ROSEN, MICHAEL R
ROSEN, MICHAEL R
ROSEN, MICHAEL R
ROSENBAUM, ROBERT
M
ROSENBERG, ANDREAS
ROSENBERG, ANDREAS
ROSENBERG, ROBERT D
ROSENBLOOM, JOEL
ROSENBLUM, WILLIAM
ROSENBLUM, WILLIAM
ROSENBLUM, WILLIAM
ROSENMAN, RAY H
ROSENQUIST, GLENN C
ROSENSTEIN, BERYL J
ROSENSTOCK, IRWIN M
ROSENTHAL, AMNON
ROSKA, A KAY
ROSKOSKI, ROBERT, J
ROSKOSKI, ROBERT, J
ROSS, CHARLES R
ROSS, GORDON
ROSS, JOHN, JR
ROSS, JOHN, JR
ROSS, JOHN, JR
ROSS, JOHN, JR
ROSS, RUSSELL
ROSS, RUSSELL
ROSSEN, ROGER D
ROSSEN, ROGER D
ROTH, EUGENE F, JR
ROTH, EUGENE F, JR
ROTH, GERALD J
ROTH, JEROME A
ROTHBLAT, GEORGE
ROTHBLAT, GEORGE
ROTHE, CARL F
ROUSH, ROBERT E
ROVETTO, MICHAEL J
ROWE, A W
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P01HL22633-01 9001
R01HL07723-15
P60HL17269-04 0037
R01HL1789504
P01HL09011-15 0022
ALPHABETICAL LISTING OF INVESTIGATORS
i
ROWELL, LORING B
ROWLANDS, DAVID T
ROWLANDS, DAVID T
ROWLANDS, DAVID T
ROWLEY, PETER T
RUBENFIRE, MELVYN
RUBENSTEIN, ARTHUR
RUBERMAN, WILLIAM
RUBERMAN, WILLIAM
RUBINSTEIN, PABLO
RUBIO, RAFAEL
RUCKER, ROBERT B
RUCKER, ROBERT 8
RUCKNAGEL, DONALD L
RUDEL, LAWRENCE L
RUDEL, LAWRENCE L
RUDNICK, GARY W
RUDOLPH, ABRAHAM M
RUDOLPH, ABRAHAM M
RUDOLPH, ABRAHAM M
RUDOLPH, ABRAHAM M
RUDOLPH, ABRAHAM M
RUDOLPH, STEPHEN A
RUPLEY, JOHN A
RUSH, BENJAMIN F, J
RUSH, STANLEY
RUSKIN, JEREMY N
RUSSELL, DIANE H
RUSSELL, JAMES A
RUSSELL, MICHAEL L
RUSSELL, PAUL S
RUSSELL, PAUL S
RUSSELL, PAUL S
RUTHERFORD, ROBERT
RYAN, JAMES W
RYAN, JAMES W
RYAN, STEPHEN F
RYAN, UNA S
RZESZOTARSKI, WACLA
SABBADINI, ROGER
SABESIN, SEYMOUR M
SABESIN, SEYMOUR M
SABISTON, DAVID C,
SACHS, FREDERICK
SACHS, HOWARD G
SACKNER, MARVIN A
SAGAWA, KIICHI
SAGAWA, KIICHI
SAGAWA, KIICHI
SAID, SAMI I
SAID, SAMI I
SAIDE, JUDITH D
SAKURA, J DAVID
SALEN, GERALD
SALGANICOFF, LEON
SALSER, WINSTON A
SALTZMAN, ALAN R
SALZANO, JOHN V
SALZANO, JOHN V
SALZMAN, EDWIN W
SALZMAN, EDWIN W
SALZMAN, EDWIN W
SALZMAN, EDWIN W
SALZMAN, EDWIN W
SAMPSON, SANFORD R
SAMUEL, P
SAMUEL, PAUL
SAMUELS, ALLAN I
SANBORN, WARREN G
SANCES, ANTHONY, JR
SANDBERG, WWRENCE
SANDBERG, LAWRENCE
SANDBERG, LAWRENCE
SANDERS, A P
SANDERS, TOMMY M
SANT'AMBROGIO, GIUS
SANTISTEBAN, GEORGE
SAROESAI, VISHWANAT
SASHIN, DONALD
SATCHER, DAVID
SATCHER, DAVID
SATIR, PETER
SAUDEK, CHRISTOPHER
SAUM, WILLIAM R
SAUNDERS, NICHOLAS
SAUnER, RICHARD D
SAUVAGE, LESTER R
SAWATANI, SATOSHI
SAWYER, W H
SAWnrER, W H
SAYEED, MOHAMMED M
SAYEED, MOHAMMED M
P01HL1691005 0006
P50HL1 506 1-07 0006
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R01HL2126002
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R01HL21995-01
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SCALES, DONALD
SCALLEN, TERENCE J
SCANU, ANGELO M
SCANU, ANGELO M
SCANU, ANGELO M
SCANU, ANGELO M
SCARPA, ANTONIO
SCARPA, ANTONIO
SCARPELLI, EMILE M
SCHACHTER, DAVID
SCHACHTER, JOSEPH
SCHAEFER, WILLIAM P
SCHAFFER, STEPHEN W
SCHAMBELAN, MORRIS
SCHANFIELD, MOSES S
SCHANKER, LEWIS S
SCHEIDT, STEPHEN
SCHEIDT, W ROBERT
SCHEINMAN, MELVIN M
SCHENK, WORTHINGTON
SCHENK, WORTHINGTON
SCHENK, WORTHINGTON
SCHENK, WORTHINGTON
SCHENK, WORTHINGTON
SCHENK. WORTHINGTON
SCHER, ALLEN M
SCHER, ALLEN M
SCHER, ALLEN M
SCHERAGA, HAROLD A
SCHERER, PETER W
SCHERLAG, BENJAMIN
SCHEUER, JAMES
SCHEUER, JAMES
SCHEUER, PAUL J
SCHICK, PAUL K
SCHICK, PAUL K
SCHIFFMAN, SANDRA
SCHIFFMAN, SANDRA
SCHILLER, NELSON B
SCHLANT, ROBERT C
SCHLANT, ROBERT D
SCHLENK, HERMANN
SCHLENK, HERMANN
SCHLESINGER, PAUL H
SCHLESSINGER, RICHA
SCHLISELFELD. LOUIS
SCHLOERB, PAUL R
SCHLUETER, DONALD P
SCHLUETER, DONAtO P
SCHMID, HARALD H 0
SCHMID, HARALD H 0
SCHMID, KARL
SCHMID, KARL
SCHMID, PHILLIP G
SCHMID, PHILLIP G
SCHMID, PHILLIP G
SCHMID, PHILLIP 6
SCHMIDT-NIELSEN, KN
SCHMIDT-NIELSEN, KN
SCHMIDTKE, JON R
SCHMin, OTTO H
SCHNEIDER, EDWARD G
SCHNEIDERMAN, GARY
SCHOENBERGER, JAMES
SCHOENBERGER, JAMES
SCHONFELD, GUSTAV
SCHONFELD, GUSTAV
SCHONFELD, GUSTAV
SCHORK, MICHAEL ANT
SCHOTZ, MICHAEL C
SCHRAMM, LAWRENCE
P
SCHREIBER, AUN D
SCHREIBER, SIDNEY S
SCHROEDER, JOHN
SCHROEDER, JOHN S
SCHROEDER, JOHN S
SCHROEDER, JOHN S
SCHROEDER, WALTER A
SCHROEDER, WALTER A
SCHROEPFER, GEORGE
SCHROEPFER, GEORGE
SCHROn, HELMUT G
SCHUDER, JOHN C
SCHUDER, JOHN C
SCHUESSLER, GEORGE
SCHULL, WILLIAM J
SCHULTZ, DUANE R
SCHULZ, HORST H
SCHUSTER, TODD M
SCHUTZBACH, JOHN
SCHWARTZ, ARNOLD
598
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■15
■05
■01
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■01
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12 0105
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SCHWARTZ, ARNOLD
SCHWARTZ, ARNOLD
SCHWARTZ, ARNOLD
SCHWARTZ, JEFFREY
SCHWARTZ, JEFFREY S
SCHWARTZ, JOEL M
SCHWARTZ, SEYMOUR I
SCHWARTZ, SORELL L
SCHWARTZ, STEPHEN M
SCHWARTZ, STEPHEN M
SCHWARZ, MARVIN I
scon, R FOSTER
SCOn, RALPH C
SCOTT, ROLAND B
SCOTT, ROLAND B
SEALEY, JEAN E
SEALEY, JEAN E
SEALEY, JEAN E
SEALY, WILL C
SEAMAN, GEOFFREY V
SEAMAN, GEOFFREY V
SEEGERS. WALTER H
SEEGERS, WALTER H
SEIDEL, JOHN C
SEIDEL, JOHN C
SEITER, CHARLES H
SELLS, CLIFFORD J
SELVESTER, RONALD H
SELVESTER, RONALD H
SELVESTER, RONALD H
SELZER, ROBERT
SENAY, LEO C, JR
SENIOR, ROBERT M
SENTERFIT, B LAUREN
SERUR, J R
SEVERINGHAUS, JOHN
SEVERINGHAUS, JOHN
SEVERS, WALTER B
SEYMOUR, F R
SHAEFFER, JOSEPH R
SHAFFER, THOMAS H
SHAINOFF, JOHN R
SHAINOFF, JOHN R
SHAINOFF, JOHN R
SHAINOFF, JOHN R
SHAMMA, MAURICE
SHAND, DAVID G
SHAND, DAVID G
SHANNER, WILLIAM M
SHANNON, ROGER
SHAPIRO, ALVIN P
SHAPIRO, ASCHER H
SHAPIRO, DAVID
SHAPIRO, DAVID J
SHAPIRO, SANDOR S
SHAPIRO, SANDOR S
SHAPIRO, SANDOR S
SHARE, LEONARD
SHARE, LEONARD
SHARMA, M G
SHARP, JOHN T
SHAY, JERRY W
SHEFFIELD, L THOMAS
SHEFFIELD, THOMAS L
SHELL, WILLIAM
SHELL, WILLIAM E
SHELL, WILLIAM E
SHEPHERD. ALBERT P,
SHEPHERD, JOHN T
SHEPHERD, JOHN T
SHEPHERD, JOHN T
SHEPHERD, JOHN T
SHEPHERD, JOHN T
SHEPHERD, JOHN T
SHEPHERD, JOHN T
SHEPHERD, JOHN T
SHEPHERD, JOHN T
SHEPPARD, JOHN
SHEPPARD, LOUIS C
SHEPPARD, LOUIS C
SHEPPARD, LOUIS C
SHEPRO, DAVID
SHERBURNE, STUART W
SHERIDAN, JUDSON D
SHERMAN. UURENCE A
SHERRY, SOL
SHERWIN. ROGER W
SHIDEMAN, FREDERICK
SHIH, JASON C H
SHINE, KENNETH I
SHORE, JOSEPH D
SHORE, VIRGIE G
R01HL22039-02
P0IHL22619-01
P01HL226 19-01 0003
R01HL22612-01
R23HL2 1298-02
R01HL13585-05
R01HL1346608
P01HL16748-05 0001
P01HL03174-23 0001
P01HL18645-03 0005
R01HL1901803
P01HL20993-02 0002
R01HL20428-03
P60HL15160-07
P60HL15160-07 0017
P50HL18323-04 0033
P50HL18323-04 0045
R01HL21274-01
R01HL13920-07
R01HL18284-04
R01HL19255-03
R01HL03424-21
R01HL18435-03
R01HL15391-07
R01HL2324901
R01HL19392-03
P50HL19187-02 0007
P50HL1413805 0010
R01HL14688-05
R01HL17532-04
P50HL14138-05 0016
R01HL21282-01
P01HL16 118-06 0004
R01HL01803-23 0016
R01HL20895-03 0006
P01HL06285-18 0146
P01HL06285-18 0147
R01HL19320-03
R01HL1737203
R01HL24021-02
R01HL22843-01
P01HL0683517 0027
P01HL06835-17 0028
R01HL16361-03
R01HL19767-01
R01HL12971-15
P50HL14192-08 0001
R01HL23726-01
N01HR72974-01
R01HL17715-04
R01HL20724-01
R01HL17974-03
R01HL19568-03
R01HL17882-04
N01HB53018-04
N01HB53035-04
R01HL0916313
R01HL12990-09
R01HL19209-03
R01HL11289-12
R01HL08789-11
R01HL20643-02
N01HV12159-09
POIHLI 1310-12 0092
P50HL17651-04 0036
P50HL17651-04 0039
P50HL17651-04 0041
R01HL18080-03
R01HL05883-18
R01HL05883-18 0001
R01HL05883-18 0002
R01HL0588318 0003
R01HL05883-18 0004
R01HL05883-18 0005
R01HL05883-18 0006
R01HL05883-18 0007
R01HL05883-18 0008
P01HL06314-17 0055
P01HL11310-12 0058
P01HL11310-12 0065
POIHLI 1310-12 0066
R01HL16714-05
R01HL19163-02
P01HL06314-17 0054
P50HL1414708 0006
P50HL1421708
N01HV22980-06
R01HL2079302
R01HL21912-01
P01HL11351-12 0015
R01HL13035-08
ROIHLI 7463-03
599
ALPHABETICAL LISTING OF INVESTIGATORS
SHOUKAS. ARTIN A
SHUG. AUSTIN L
SHUMAN. MARC A
SHUMWAY. NORMAN E
SHUMWAY, NORMAN E
SHUMWAY. NORMAN E
SHUMWAY. NORMAN E
SHUMWAY. NORMAN E
SHUMWAY. NORMAN E
SHUMWAY. NORMAN E
SHUMWAY. NORMAN E
SHUMWAY. NORMAN E
SHUMWAY. NORMAN E
SHUMWAY. NORMAN E
SIEGEL. BARRY A
SIEGEL. JOHN H
SIEGMAN. MARION J
SIEGMAN. MARION J
SIERVOGEL. ROGER M
SIGLER. PAUL B
SIGN. CHARLES F
SILBERBERG. ALEXANO
SILK. SUSAN T
SILVER. DONALD
SILVER. MELVIN J
SILVERBERG. SIDONIE
SILVERSTEIN. EMANUE
SIMON. GEZA
SIMON. MORRIS
SIMON. MORRIS
SIMON, S A
SIMON. TOBY L
SIMONI, ROBERT 0
SIMONS. ELIZABETH R
SIMONS, ELIZABETH R
SIMPSON, FREDERIC 0
SIMPSON, JOHN B
SIMPSON, JOHN B
SIMPSON. LANCE L
SING, CHARLES F
SINGER, THOMAS P
SINGER, THOMAS P
SINGER, THOMAS P
SINGER, THOMAS P
SINGER, THOMAS P
SINGH, BRAMAH N
SINGH. BRAMAH N
SINGH. BRAMAH N
SINGH. DIWAN
SIPERSTEIN. MARVIN
SIPERSTEIN, MARVIN
SIPERSTEIN. MARVIN
SIPERSTEIN. MARVIN
SIPERSTEIN, MARVIN
SKALAK, RICHARD
SKALAK. RICHARD
SKEGGS, LEONARD T
SKINNER. DAVID 8
SKINNER. JAMES E
SKINNER, NEWMAN S,
SKOULTCHI, ARTHUR
SLACK, HUBERT R
SLACK, HUBERT R
SLACK, HUBERT R
SLAKEY. LINDA L
SLATER, EVE E
SLATON, PAUL E
SLAYTER, HENRY S
SLEATOR, WILLIAM W
SLIGHTER, SHERRILL
SLOME, CECIL
SLOTKOFF, LAWRENCE
SLOTKOFF, LAWRENCE
SMALL, DONALD
SMALL, DONALD M
SMITH L. RICHARD
SMITH, EDWARD J
SMITH, FRANK R
SMITH. FRED
SMITH. FRED G, JR
SMITH, J BRYAN
SMITH, JAMES R
SMITH, JOSEPH E
SMITH, KEVIN M
SMITH, KIRBY D
SMITH, LELAND L
SMITH, LINDA L
SMITH, LOUIS C
SMITH, LOUIS C
SMITH, LOUIS C
SMITH, LYNWOOD S
SMITH. ORVILLE A
R01HL1903903
R01HL1773604
R01HL2140302
R01HL08696I5
R01HL08696 15 0001
R01HL0869e 15 0004
R01HL08696 15 0010
R01HL08696 15 0011
R01HL08696 15 0012
R01HL08696 15 0013
R01HL08696 15 0014
R01HL08696-15 0018
R01HL08696 15 0019
R01HL0869615 0020
P50HL14147 08 0016
R01HL1567606
P01HL15835-06 0012
R01HL23205-01
R01HL23194-02
P60HL1600505 0015
P60HL1600806 0016
N01HV5290704
R23HL2 149002
R01HL18815-03
R01HL1489007
R01HL22955-01
R01HL19077-01
R01HL2167301
P01HL1141411 0027
R01HL20554-02
P01HL12157-11 0038
P60HL1726504 0007
R01HL1821904
R01HL15335-06
R01HL16375-04
R01HL1094209
R01HL21799-01
R01HL21800-01
P01HL1273810 0065
P60HL1600806 0012
P01HL1625106
P01HL16251-06 0007
P01HL16251-06 0008
P01HL16251-06 0009
P01HL16251-06 0010
P50HL17651-04 0046
P50HL17651-04 0048
R01HL23970-01
R23HL22984-01
P01HL06285-18 0149
P01HL0628518 0150
P01HL06285-18 0151
P01HL06285-18 0152
P01HL06285-18 0207
P01HL15832-06 0005
P01HL16851-04 0003
R01HL17243-05
P50HL1 7648-04 0011
R01HL17907-04
ROIHLI 5562-05
P01HL21016-02 0012
P60HL17292-04 0018
P60HL17292-04 0020
P60HL1 7292-04 0021
R01HL22486-01
R23HL21247-02
P50HL1419208 0007
R01HL22270-01
R01HL13349-06
P60HL1 7265-04 0006
R01HL18175-03
R01HL12827-08
N01HV72915-02
P01HL13262-07 0025
R01HL1862312
P50HL1 7667-04 0044
R01HL12564-09
P50HL21006-02 0002
R23HL21251-01
P01HL14388-07 0188
R01HL21239-02
R01HL21009-02
R01HL1297209
R01HL2225201
R01HL15026-12
R01HL10160-13
R01HL19456-03
R01HL15648-06
P60HL1 7269-04 0015
P60HL1 7269-04 0045
R01HL16254-05
P01HL16910-05 0007
SMITH, ROGER P
SMITH. THOMAS W
SMITH. THOMAS W
SMITH. WILLIAM M
SMITHtRMAN, THOMAS
SNELL. lAMES D
SNELL. JAMES 0
SNIDER. GORDON L
SNIDER, GORDON L
SNIDER, GORDON L
SNIDER, GORDON L
SNIDER, GORDON L
SNIDER. GORDON L
SNIDER. GORDON L
SNIDER, GORDON L
SNIDERMAN. ALLAN D
SNOW. T RUSSELL
SNYDER, FRED L
SNYDER, ROBERT L
SOBEL, BURTON E
SOBEL, BURTON E
SOBEL. BURTON E
SOBEL, BURTON E
SOBEL, BURTON E
SOBEL, BURTON E
SOBIN, SIDNEY S
SOBIN, SIDNEY S
SOBIN, SIDNEY S
SOFFER, RICHARD L
SOLARO, R JOHN
SOLARO, R JOHN
SOLARO, R JOHN
SOLOMON. ARTHUR K
SOLOWAY, ROGER D
SOMANI, PITAMBAR
SOMLYO, ANDREW P
SOMLYO, ANDREW P
SOMMER, JOACHIM R
SONNENBLICK. EDMUND
SONNENBUCK. EDMUND
SONNENBLICK. EDMUND
SONNENSCHEIN. RALPH
SORDAHL, LOUIS A
SOUHRADA, JOSEPH F
SOUTHARD, JOHN W
SPACH, MADISON S
SPACH, MADISON S
SPAET, THEODORE H
SPAET, THEODORE H
SPAET, THEODORE H
SPALTER, HAROLD F
SPANN, JAMES F, JR
SPARGO, BENJAMIN H
SPARGO, BENJAMIN H
SPARK, RICHARD F
SPARKS, HARVEY V
SPARKS, HARVEY V
SPARKS, ROBERT E
SPARROW, JAMES T
SPATH, JAMES A, JR
SPATH, JAMES A, JR
SPEAR, JOSEPH F
SPECTOR, ARTHUR A
SPECTOR, ARTHUR A
SPECTOR, ARTHUR A
SPENCER, MERRILL P
SPERELAKIS, NICK
SPERELAKIS, NICK
SPICER, SAMUEL S
SPIRO, THOMAS G
SPIVAK, JERRY L
SPOCK, A
SPOTNITZ, H
SPOTNITZ, HENRY H
SPOTNITZ, HENRY H
SPOTNITZ, HENRY M
SPRAGG, JOCELYN
SPRUNT, KATHARINE
SRINIVASAN, S R
ST JOHN, WALTER M
STAFFORD, WALTER F,
STAHLMAN, MILDRED T
STAHLMAN, MILDRED T
STAHLMAN, MILDRED T
STAHLMAN, MILDRED T
STAHLMAN. MILDRED T
STAMATOYANNOPOULOS,
STAMLER, JEREMIAH
STAMLER, JEREMIAH
STAMLER, JEREMIAH
STAMMER, CHARLES H
STANDAERT, THOMAS A
R01HL14127 16
ROIHL 18003 05
P01HL1925903 0004
R0IHL10711 12
P50HL 17669 04 0002
P50HL1421407 0012
P50HL 19 15302 0006
P01HL1971702 0008
P01HL1971702 0013
PO1HL1971702 0014
P01HL1971702 0015
P01HL1971702 0018
P01HL1971702 0019
P01HL1971702 0020
P01HL1971702 0021
R01HL2209801
P50HL 17670-04 0022
R01HL18181-04
R01HL01979-22
P50HL17646-04
P50HL 17646-04 0001
P50HL1 764604 0005
P50HL17646-04 0009
P50HL17646-04 0017
N01HV72941-02
R01HL11152-12
R01HL23224-01
N01HR62910-02
R01HL2139402
R01HL2223102
P01HL22619-01 0006
P01HL226 19-01 0009
R01HL14820-07
P01HL0889914 0061
R01HL18599-02
P01HL15835-06
P01HL15835-06 0019
R01HL1248610
R01HL18824-03
R01HL20426-03
R01HL21993-01
R01HL17903-03
R01HL23153-01
R01HL17322-04
N01HV72986-02
P01HL11307-12
POIHLI 1307-12 0002
P01HL16387-04
P01HL16387-04 0003
P01HL16387-04 0005
R01HL14148-07 0004
R01HL17631-05
R01HL02986-21
R01HL10980-11
P01HL11414-11 0014
R01HL16760-05
R01HL20399-03
R01HL18764-03
P60HL1 7269-04 0013
R01HL20283-02
R01HL21452-02
R01HL19045-03
P50HL14230-07
P50HL14230-07 0092
R01HL14781-08
R01HL19341-03
R01HL1871103
P01HL19242-02 0009
P50HL19160-02 0002
R01HL12526-09
R01HL21692-02
P01HL07896-15 0043
P01HL12738-10 0130
P01HL12738-10 0094
P01HL12738-10 0098
R01HL22894-01
R01HL22939-0I
P50HL14218-07 0005
P50HL15103-07 0013
R01HL20574-03
R23HL21488-01
P50HL14214-07
P50HL14214-07 0027
P50HL14214-07 0032
P50HL14214-07 0034
R01HL22520-01
R01HL20899-02
R01HL15174-06
R01HL15374-03
R01HL21010-02
R01HL17896-03
P50HL19187-02 0013
STANKUS, KATHERINE
STANKUS. KATHERINE
STARCHER. BARRY C
STARK. ANN R
STARR, ALBERT
STARY. HERBERT C
STAUB, NORMAN C
STAUB. NORMAN C
STAUB. NORMAN C
STAUB, NORMAN C
STCLAIR, RICHARD W
STCLAIR, RICHARD W
STCLAIR, RICHARD W
STCLAIR, RICHARD W
STEELE, THOMAS H
STEER, MICHAEL L
STEIN, YECHEZKIEL
STEINBERG, DANIEL
STEINBERG. DANIEL
STEINBERG. DANIEL
STEINBERG. DANIEL
STEINBERG. DANIEL
STEINER. MANFRED
STEINER, MANFRED
STEINHARDT, JACINTO
STEINMETZ, PHILIP R
STEINSLAND. ODD S
STEKIEL. WILLIAM J
STELLWAGEN. EARLE
STEMERMAN. MICHAEL
STEMERMAN. MICHAEL
STEMMERMANN. GRANT
STENT, GUNTHER S
STERN, ARNOLD
STEVENS, CLADD E
STEVENS, PAUL M
STEWART, DOUGUS K
STEWART. DOUGLAS K
STEWART. DOUGLAS K
STEWART. GWENDOLYN
STEWART, JOHN M
STILL, WILLIAM J
STINSON, EDWARD B
STINSON, EDWARD B
STINSON, EDWARD B
STOECKENIUS, WALTHE
STOECKENIUS, WALTHE
STOECKENIUS, WALTHE
STOECKENIUS, WALTHE
STOLWIJK, JAN A
STONE, HUBERT L
STONE, HUBERT L
STONE, HUBERT L
STONE. MARVIN J
STONE, PHILIP J
STONE, RICHARD A
STONER, CLINTON D
STOREY. BAYARD T
STORK, GILBERT
STOSSEL, THOMAS P
STOUT. MARGUERITE A
STOWE. DAVID F
STOWE, N T
STRACHER, ALFRED
STRACHER, ALFRED
STRANDNESS, D EUGEN
STRANDNESS, D EUGEN
STRANDNESS, DONALD
STRANDNESS, DONALD
STRANDNESS, DONALD
STRAUSS, H WILLIAM
STRAUSS. HAROLD C
STRAUSS. HAROLD C
STRAUSS, RONALD G
STREETEN, DAVID H
STREETER, DANIEL D,
STREIDER, DENISE J
STRIKER, GARY E
STROBER, SAM
STRONG, JACK P
STRONG, WILLIAM B
STROUD, FLORENCE M
STROUD. ROBERT M
STULL, JAMES T
STULL, JAMES T
STUMPF, WALTER E
SU, CHE
SU. CHE
SU, JUDY Y
SUBBIAH, RAVI M
SUDDATH, FRED L
SULLIVAN, JAY M
P50HL 1/65 104 0033
P50HL 1765 104 0034
P01HLI6118 06 0003
R23HL2140501
R01HLI646105
R01HL2273901
P01H106285 18 0145
P50HL 1915502
P50HL19155 02 0004
P50HL1915502 0005
P50HL1416407 0034
P50HL1416407 0035
P50H114164 07 0036
P50HL1416407 0037
R01HL2283601
R01HL20956-02
N01HV53015 09
P01HL12373-10 0006
P50HL1419707
P50HL14197-07 0005
R01HL22053-02
N01HV1216015
R01HL1932303
R01HL2295101
R01HL1225615
P01HL14388-07 0191
R01HL20439-02
R01HL16454-03
P01HL14388-07 0175
P01HL11414-11 0037
P01HL22602-01 0004
N01HV62955-04
R01HL2222701
R01HL19532-01
R01HL22838-01
N01HR72905-03
P01HL07293-17 0041
P01HL0729317 0053
R01HL1945103 0003
P50HL1421708 0050
N01HV72946-02
R01HL09622-14
P01HL13108-09
P01HL1310809 0001
R01HL17993-04 0001
P01HL06285-18 0211
P01HL06285-18 0212
P01HL0628518 0213
P01HL06285-18 0214
R01HL17732-03
R01HL18798-04 0003
R01HL22154-01
R01HL23206-01
P50HL1 7669-04 0001
P01HL19717-02 0003
R01HL18095-04
R01HL18038-03
P01HL19737-02 0013
R01HL16471-05
R01HL19429-03
R23HL21213-01
R23HL21434-02
P01HL06835-17 0061
R01HL14020-06
R01HL20666-02
P01HL07293-17 0054
P01HL07293-17 0058
R01HL20381-03
R01HL20898-02
R01HL21572-01
P50HL1 7665-04 0027
P50HL17670-04 0011
R01HL19216-03
N01HB62973-05
R01HL22051-01
R01HL20883-02
P01HL10436-13 0005
P01HL03174-23 0005
P01HL13108-09 0016
P01HL08974-14
P60HL15158-07 0025
R01HL22212-01
P01HL11310-12 0096
P50HL1 7682-04 0024
R01HL23990-01
R01HL22079-01
P01HL20581-01 0004
P01HL20581-01 9002
R01HL20754-02
R01HL18610-03
R01HL21170-O1
R01HL2152301
ALPHABETICAL LISTING OF INVESTIGATORS
SULLIVAN, STUART F
SUNDELL, HAKAN
SUNDELL, HAKAN
SUNDELL, HAKAN
SUNG, MICHAEL T
SURWIT, RICHARD S
SUSSMAN, IRA I
SUTERA, SALVATORE P
SUTKO, JOHN L
SWAN, HAROLD J
SWAN, HENRY
SWAN, KENNETH G
SWEELEY, CHARLES C
SWENSON, CHARLES A
SWIFT, DAVID L
SWITALSKI, RICHARD
SWITZER, MARY E
SYLVESTER, JIMMIE T
SYLWESTER, DAVID L
SYNHORST, DAVID P
SZABO, ATTILA
SZABO, GABOR
SZABO, SANDOR
SZMUNESS, WOLF
SZMUNESS, WOLF
SZMUNESS, WOLF
SZMUNESS, WOLF
TACKER, WILLIS A, J
TACKER, WILLIS A, J
TAEGTMEYER, HEINRIC
TAEGTMEYER, HEINRIC
TAEGTMEYER, HEINRIC
TAGER, IRA B
TAKEDA, YASUHIKO
TALAMO, RICHARD C
TAWMO, RICHARD C
TALAMO, RICHARD C
TALL, AWN R
TAN, SIANG Y
TANNER, GEORGE A
TARAZI, ROBERT C
TARR, CHARLES M
TAUB, EDWARD
TAUBERT, KATHRYN A
TAUSSIG, LYNN M
TAUSSIG, LYNN M
TAYLOR, AUBREY E
TAYLOR, AUBREY E
TAYLOR, AUBREY E
TAYLOR, AUBREY E
TAYLOR, EDWIN WILLI
TAYLOR, FLETCHER B,
TAYLOR, FLETCHER B,
TAYLOR, FLETCHER B,
TAYLOR, FRED M
TAYLOR, HENRY
TAYLOR, HENRY L
TAYLOR, JOHN F
TAYLOR, KENNETH B
TELLEZ-NAGEL, ISABE
TEMPLE, PATRICIA C
TEMPLETON, GORDON H
TENG, LIN-NAR L
TENNEY, STEPHEN M
TER-POGOSSIAN, MICH
TERRAGNO, NORBERTO
THADEPALLI, HARAGOP
THAMES, MARC D
THEROUX, PIERRE A
THOMAS. WILBUR A
THOMAS, JAMES A
THOMAS, WILBUR A
THOMAS, WILBUR A
THOMAS, WILBUR A
THOMASSEN, MARY JAN
THOMPSON, ARTHUR R
THOMPSON, BRIAN J
THURSTONE, FREDRICK
TIELL, MELVIN L
TIERNEY, DONALD F
TIMMS, RICHARD M
TIPTON, CHARLES M
TITUS, JACK L
TITUS, JACK L
TITUS, JACK L
TOBIAN, LOUIS
TOCKMAN, MELVYN S
TOMANEK, ROBERT J
TOOLEY, WILLIAM H
TOONEY, NANCY M
TOONEY, NANCY M
TORMEY, JOHN MCD
R01HL17358-04
P50HL14214-07 0026
P50HL14214-07 0029
P50HL14214-07 0035
R01HL2030002
R01HL22547-01
P01HL16387-04 0008
R01HL12839-09
R23HL2126202
P50HL1 765 1-04
R01HL2 1969-01
R01HL18096-04
R01HL17462-03
P01HL14388-07 0173
R01HL19715-02
N01HB62968-07
R23HL21208-02
P01HL10342-13 0023
P50HL1421207 0017
R23HL2 1203-02
R01HL21483-01
R01HL19639-02
P01HL06370-17 0015
N01HB62908-07
P01HL09011-15 0018
P01HL09011-15 0020
P01HL09011-15 0023
R01HL22699-01
R01HL22759-01
P50HL1 7665-04 0029
P01HL20552-02 9003
R01HL21381-02
R01HL22528-02
ROIHL 11686-09
P50HL19157-02
P50HL19157-02 0007
P50HL19157-02 0008
R01HL22682-01
R23HL21291-02
R01HL13929-06
R01HL15837-06
R01HL18943-03
R01HL21323-02
R23HL22575-01
P50HL14136-07 0017
P50HL14136-07 9006
POIHLI 1678-11 0036
P01HL11678-11 0039
R01HL22549-02
R01HL22569-02
P01HL20592-02 0001
P01HL17812-04
P01HL17812-04 0001
P01HL17812-04 0004
P60HL1 7269-04 0038
R01HL20662-02
R01HL16909-04
R01HL22780-01
R01HL20116-01
P01HL21016-02 0018
P60HL20985-01 0001
P50HL1 7669-04 0007
R01HL22035-01
R01HL02888-22
P01HL13851-16
R01HL22225-01
R01HL20963-01
R01HL21 158-02
N01HV82910-00
P01HL20993-02 0013
R01HL13630-08
P01HL20993-02
P01HL20993-02 0001
P01HL20993-02 0003
R01HL13885-08 0007
P60HL1 7265-04 0003
POIHL 18208-04 0002
R01HL12715-10
P01HL16387-04 0009
R01HL17719-03
N01HR62946-04
R01HL21245-02
P60HL1 7269-04 0001
P60HL1726904 0004
P60HL1 7269-04 0007
P01HL17871-04
P50HL14153-07 0010
R01HL18629-04
P50HL19185-02 0011
P01HL17419-04 0007
R01HL18533-03
P01HL11351-12 0018
TORNHEIM, PATRICIA
TOWNSEL, JAMES G
TRACY, RICHARD E
TRACY, RICHARD E
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TRAYLOR, TEDDY G
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TRELSTAD, ROBERT L
TRELSTAD, ROBERT L
TRENTIN, JOHN J
TRIGGLE, DAVID J
TRILLO, ALBERTO
TRINER, L
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VRACKO, RUDOLF
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WADE, CHARLES G
WAGNER, F WILLIAM,
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WILLMAN. VALLEE L
WILLMAN. VALLEE L
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WILLMAN. VALLEE L
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ALPHABETICAL LISTING OF INVtSTIOATORS
YIPINTSOI, TADA
YODA, ATSUNOBU
YONCE, LLOYD R
YONETANI, TAKASHI
YOSHIDA, AKIRA Y
YOSHIDA, AKIRA Y
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YOUNG. DAVID B
YOUNG, DAVID B
YOUNG, DAVID B
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YU, JOHN C
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YU, SHIU YEH
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ZIMMERMAN, BEN G
ZIMMERMAN, HERBERT
ZIMMERMAN,
THEODORE
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THEODORE
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DHEW Publication No. (NIH) 79-705
Live Music Archive
Librivox Free Audio
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