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J  2. 


North  Carolina  State  LiDrary 


STUDIES 


N.  a 

Doa 


A  SPECIAL  REPORT  SERIES  BY  THE  N.C.  DEPARTMENT  OF  HUMAN  RESOURCES,  DIVISION  OF 
HEALTH  SERVICES,  STATE  CENTER  FOR  HEALTH  STATISTICS,  P.O.  BOX  2091,  RALEIGH,  N.C.  27602 


No.  18 


ji^^^ 


o 


\9S0 


August  I9B0 


WIDE  GAPS  IN  MORTALITY  RISK: 
COMPARISONS  AMONG  RACE-SEX  GROUPS 
ACROSS  TIME  AND  SPACE  DIMENSIONS 


Effective  May  1,    1980,    the  State  Center  for  Health  Statistics  was  created. 
Accordingly y   our  special-study  monograph  series  has  a  new  name — SCES  STUDIES  replacing 
the  former  PHSB  STUDIES.      In  the  future,   we  hope  to  be  more  prolific  than  in  the  recent 
past,   and  as  always,   we  welcome  your  suggestions  for  improvement.      Now  to  the  subject 
at  hand  .    .    . 

For  many  conditions  contributing  to  death,  prevention  is  possible  and  chances  of 
survival  are  good  when  cases  are  diagnosed  and  treated  at  an  early  stage.   Hence, 
through  the  analysis  of  risk  patterns  among  population  groups,  public  health  programs 
can  play  a  major  role  in  reducing  morbidity  and  mortality  by  concentrating  their  efforts 
on  those  groups  at  greatest  risk. 

As  discussed  in  a  prior  publication  on  leading  causes  of  mortality  in  North 
Carolina  (1),  certain  causes  of  death  are  associated  with  wide  gaps  between  the  sexes 
and  between  races  with  males  and  nonwhites  experiencing  substantially  higher  death 
rates  than  their  female  and  white  counterparts.   In  particular,  the  publication  reveals 
the  following  recent  patterns  in  North  Carolina: 

-  Male  death  rates  approach  or  exceed  twice  the  female  rates  for  8 
major  causes:   acute  myocardial  infarction,  lung  cancer,  chronic 
obstructive  lung  diseases,  motor  vehicle  and  other  accidents, 
cirrhosis,  suicide  and  homicide. 

-  Nonwhite  death  rates  approach  or  exceed  twice  the  white  rates  for 
6  causes:  cancer  of  the  stomach,  cervix,  prostate;  hypertension; 
nephr i t i s/nephrosis  and  homicide. 

Differential  age  structures  can  account  for  mortality  differences  since,  obviously, 
an  older  population  will  experience  more  deaths  and  hence  higher  death  rates  unless  we 
adjust  for  age.   Thus,  in  order  to  identify  those  race-sex  groups  most  in  need  of 
particular  kinds  of  service,  the  present  effort  examines  age-adjusted  rates  for  major 
underlying  causes  of  death.   Rates  for  race-sex  groups  within  health  service  areas 
(HSA's),  North  Carolina  and  the  United  States  for  each  year  1973-77  allow  for  trending 
over  time  (final  1978  U.S.  data  are  not  available).   In  addition,  rates  for  the  period 
197^-78  are  computed  for  race-sex  groups  at  the  county,  MSA  and  state  levels.   Due  to 
the  high  costs  involved,  comparable  data  for  a  prior  time  period  have  not  been  generated. 

Consistent  with  procedures  of  the  National  Center  for  Health  Statistics  (2),  all 
rates  are  adjusted  by  the  direct  method  using  ten-year  age  intervals  and  the  19^0  Census 
of  the  total  U.S.  population  as  the  standard.   This  allows  for  comparisons  across  race- 
sex  groups,  years  and  geographical  areas.   All  U.S.  data  are  final  mortality  statistics 
published  annually  by  the  National  Center  for  Health  Statistics  as  in  reference  2. 


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Age-adjusted  Mortality:   United  States  and  North  Carolina 

Table  1  provides  U.S.  and  N.C.  rates  for  1977  with  corresponding  percent  changes 
since  1973-   For  total  deaths  and  the  five  leading  causes,  U.S.  and  N.C.  race-sex 
trends  are  depicted  in  Figures  1-6.   These  graphs  use  the  logarithmic  scale  in  order 
to  depict  the  relat  i ve  (as  opposed  to  absolute)  changes  in  death  rates. 

Age-adjusted  Mortality:   North  Carolina  Health  Service  Areas  and  Counties 

Table  2  shows  HSA  total  adjusted  rates  for  1978  and  percent  changes  since  1973. 
These  rates  show  the  greatest  differences  among  HSA's  to  involve  excessive  nonwhite 
mortality  in  the  Southern  Piedmont  and  excessive  white  mortality  in  the  Cardinal. 
In  general,  there  exists  some  tendency  towards  an  inverse  relationship  between  white 
and  nonwhite  mortality,  e.g.,  the  three  easternmost  HSA's  are  experiencing  above- 
average  white  mortality  and  below-average  nonwhite  mortality. 

Examining  cause-specific  mortality  among  the  HSA's,  Table  3  lists  an  HSA  if  its 
197^"78  cause-race-sex-specific  rate  exceeded  the  corresponding  N.C.  rate  by  10^  or 
more.   Single-year  HSA  data  for  the  period  are  also  available. 

For  counties,  five-year  total  age-adjusted  rates  for  race-sex  groups  are  depicted 
in  Figure  7  where  counties  are  grouped  according  to  quintile.   Counties  at  the  upper 
end  of  a  range  of  death  rates  should  carefully  consider  the  present  analysis  and 
request  their  own  cause-specific  data  in  order  to  ferret  out  the  causes  of  excessive 
mortality  in  one  or  more  race-sex  groups. 


Table   2 

1978  Age-adjusted   Death   Rates  with   Percent   Changes 
Since    1973.    Race-sex   Groups 

N.C.  Health  Service  Areas 


HSA 

Race  and  Sex                           | 

White 
Male 

White 
Female 

Nonwhi  te 
Male 

Nonwh  i  te 
Female 

1978 

Percent 
Change 

1978 

Percent 
Change 

1978 

Percent 
Change 

1978 

Percent 
Change 

Western 

799-5 

-10.6 

399.5 

-13.9 

1135.8 

-17.3 

702.1. 

-20.3 

Piedmont 

8U.'< 

-12.1. 

ItOli.l 

-1I..2 

121.6.7 

-  9.1 

655-9 

-20.1. 

Southern  Piedmont 

817.1 

-10.2 

1.00.7 

-12.8 

1359.7 

+  1.3 

723.2 

-16.7 

Capital 

922.6 

-  5.1. 

1.32.3 

-  9.1. 

111.7.3 

-13-9 

51.9.1 

-23-9 

Cardinal 

Sit?.  6 

-12.3 

1.57.7 

-15.1 

1155.1. 

-18.9 

620.2 

-25.2 

Eastern 

916-9 

-11.1. 

1.53.7 

-13.7 

1192.5 

-12.4 

621.8 

-18.3 

North  Carol ina 

850.9 

-11.0 

1.18.9 

-13-1. 

1201.9 

-12.1 

631.0 

-20.9 

Di  scussion 


Due  to  the  variability  often  associated  with  small  numbers,  some  counties — 
especially  western  counties — may  have  abnormally  high  or  low  rates,  especially  non- 
white  rates.   This  is  the  case  with  high  nonwhite  male  rates  in  Mitchell  and  Cherol<ee 
and  the  high  nonwhite  female  rate  in  Alleghany.   Otherwise,  age-adjusted  rates  by 
county  and  cause — available  for  the  asking — should  help  researchers  and  others  to 
"zero  in"  on  the  particular  mortality  risks  of  race-sex  groups  in  local  areas. 


The  graphs  below  display  age-adjusted  death  rates  by  race  for  sex  groups  (see 
key)  in  the  U.S.  and  N.C.   The  N.C.  data  are  shown  in  red;  the  rate  is  the 
number  of  deaths  per  100,000  population. 


RATE 

lOOOOr- 


WHITES 


I 


'■•j      w 


tool— 

73 


YEAR 


WHITES 


NONWHITES 


FIG.  1    TOTAL  MORTALITY 

Except  for  white  females,  each 
N.C.  race-sex  group  exceeds 
its  U.S.  counterpart  in  age- 
adjusted  mortality.   N.C. 
females  of  both  races  have 
recently  experienced  good  rate 
reductions  but  N.C.  males  of 
both  races  are  lagging  behind 
females  as  well  as  U.S.  males. 


FIG,  2   HEART  DISEASE  MORTALITY 

North  Carolina  males  are  at 
greater  risk  than  are  U.S. 
males,  and  reductions  in  male 
heart  disease  mortality  have 
been  less  in  North  Carolina 
than  in  the  U.S. 


FIG.  3   STROKE  MORTALITY 

For  all  four  race-sex  groups, 
stroke  mortality  is  substan- 
tially higher  in  N.C.  than  in 
the  U.S.   Rate  reductions  in 
the  state  and  nation  have  been 
comparable  except  that  N.C. 
nonwhite  females  are  slightly 
ahead  of  their  U.S.  counter- 
parts. 


NONWHITES 


NONWH I TES 

T 


The  graphs  below  display  age-adjusted  death  rates  by  race  for  sex  groups  (see 
key)  in  the  U.S.  and  N.C.   The  N.C.  data  are  shown  in  red;  the  rate  is  the 
number  of  deaths  per  100,000  population. 


RATE 
lOOO- 


WHITES 


T 


->•«- 


-*- 


lOl— 
73 


75 

YEAR 


WHITES 


FIG.  k        CANCER  MORTALITY 

For  all  but  nonwhite  males, 
North  Carolinians  are  at  less 
risk  of  death  from  cancer  than 
are  other  Americans.   However, 
except  for  nonwhite  females, 
total  cancer  mortality  is 
rising  faster  in  N.C.  than 
nationwide.   By   site, 
increases  involve  colon/rectum, 
especially  among  nonwhite 
males ;  pancreas  among  females , 
especially  nonwhites ;  lung, 
especially  females;  breast 
among  white  females  and 
prostate  among  nonwhites. 


FIG.  5 

MOTOR  VEHICLE  ACCIDENT  MORTALITY 

N.C.  exceeds  the  nation  with 
the  nonwhite  male  rate 
exceeding  the  U.S.  rate  by 
59%.   On  a  positive  note, 
however,  all  race-sex  groups 
in  N.C.  have  experienced 
higher  declines  than  their 
U.S.  counterparts.   The  N.C. 
nonwhite  female  rate  is  down 
by  more  than  half. 


RATE 
1000| 


NONWHITES 


I 


^ 


10 
73 


7M 


7S 

YEAR 


NONWHITES 


FIG.   6 


NON-MOTOR-VEHICLE  ACCIDENT  MORTALITY 


N.C.'s  recent  experience  is 
disturbing.   Not  only  do  all 
race-sex  groups,  especially 
nonwhites,  surpass  their  U.S. 
counterpcirts  in  death  rates, 
but  recent  improvements  have 
been  substantially  less  in 
N.C,  except  for  white 
females. 


NONWH I TES 

T 


Table  3 

Health  Service  Areas  Experiencing  197''-78  Age-adjusted 
Death  Rates  101  or  More  Above  Corresponding  Statewide  Rates 


Underlying 
Cause 

Race-sex 

Groups 

White  Male 

Whi  te  Female 

Nonwhi  te  Male 

Nonwhite  Female 

Heart  Disease 

Cardinal,  Eastern 

Cardinal 

S.  Piedmont 

S.  Piedmont 

Hypertens  ion 

Cardinal ,  Eastern 

Cardinal,  Eastern, 
Capital 

Cardinal ,  Eastern 

Cardinal  .  S .  Pi  edmont 

Strolce 

Cardinal,  Eastern 

Cardinal 

Eastern 

Cardinal .  Eastern 

Arter  iosclerosis 

S.  Piedmont,  Cardinal 

Cardinal 

5.  Piedmont,  Cardinal 

S.  Piedmont.  Cardinal, 
Western 

Cancer 

Eastern 

Piedmont,  S.  Piedmont 

Stomach 

Western 

Western,  Cardinal 
Eastern 

Western 

Colon/Rectum 

Piedmont,  S.  Piedmont 

Piedmont,  S.  Piedmont 

Pancreas 

Capital 

Western 

Western,  S.  Piedmont 

Western,  S.  Piedmont, 
Piedmont 

Trachea.  Bronchus 
and  Lung 

Cardinal,  Eastern 

Eastern 

Western,  S.  Piedmont, 
Capi  tal 

Female  Breast 

Capital 

Piedmont 

Cervix  Uteri 

Cardinal 

Eastern 

Ovary,  Fallopian  Tube 
and  Broad  Ligament 

Piedmont 

Western,  Eastern 

Prostate 

Piedmont 

Leukemia 

Cap! tat 

Capi  tal ,  Cardinal 

Capital ,  Piedmont 

Cardinal  ,  Piedmont , 
S.  Piedmont 

Diabetes  Hel 1 i  tus 

Cardinal 

S.  Piedmont 

S.  Piedmont,  Western, 
Piedmont 

Cardinal 

Inf luenza/Pneumon  ia 

Eastern 

Eastern 

S.  Piedmont 

Western 

Chronic  Obstructive 
Lung 

Cirrhosis  of  the  Liver 

Cardinal 

Capital,  Cardinal, 
Eastern 

Capital 

Capital ,  Cardinal  , 
S.  Piedmont,  Eastern 

Western,  Piedmont, 

S.  Piedmont 
S.  Piedmont,  Piedmont 

Western,  Capital 

Piedmont,  S.  Piedmont, 
Western 

Nephr i  t i s/Nephros i s 

S.  Piedmont.  Cardinal 

S.  Plednont,  Cardinal, 
Capital 

S.  Piedmont 

S.  Piedmont,  Cardinal, 
Piedmont 

Motor  Vehicle  Accidents 

Cardinal ,  Eastern 

Cardinal,  Eastern 

Cardinal 

Cardinal,  Eastern 

Other  Accidents 

Western,  Cardinal, 
Eastern 

Western 

Suicide 

Capital 

Capital 

Capital,  Piedmont, 
Eastern 

Western,  S.  Piedmont 

Homicide 

Western,  Cardinal 

Cardinal,  Eastern 

Western,  S.  Piedmont 

Western,  S.  Piedmont, 
Capital 

All  Causes 

Cardinal,  Eastern 

CO 
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In  this  report,  we  have  deliberately  not  shown  rates  for  total  populations  (all 
races  and  sexes  combined)  since  race  and  sex  then  become  confounding  factors. 

This  study  of  mortality  risk  has  shown  that,  after  adjustment  for  age,  wide 
gaps  exist  between  N.C.  and  the  U.S.,  and  within  N.C.,  among  HSA's,  between  the  races 
and  between  the  sexes.   In  fact,  comparisons  of  adjusted  and  unadjusted  rates  reveal 
that  adjustment  serves  to  alter  mortality  patterns  by  substantial  margins  and  in 
different  directions  in  some  cases.   For  example,  whites  of  the  Cardinal  HSA  and  non- 
whites  of  the  Southern  Piedmont  have  below-average  unadjusted  rates  but  above-average 
adjusted  rates.   Hence,  age-adjustment  is  crucial  to  the  analysis  of  mortality  risk. 

According  to  unpublished  results  of  the  Fall  1979  North  Carolina  Citizen  Survey, 
females  and  nonwhites  utilize  health  departments  more  than  males  and  whites.   Thus, 
present  findings  for  nonwhite  females  should  be  of  particular  interest  to  public 
health  administrators.   These  findings  include  the  following: 

-  Between  1973  and  1977,  N.C.  nonwhite  females  experienced 
substantial  reductions  in  age-adjusted  mortality,  leading 
other  N.C.  race-sex  groups  and  their  U.S.  counterparts  in 
reducing  total  mor*-Tlity  by  20%.   By  cause,  the  state's 
nonwhite  females  experienced  higher  reductions  than  others 
in  heart  disease,  stroke,  cancer,  chronic  obstructive  lung 
disease,  cirrhosis  and  motor  vehicle  accidents. 

-  At  the  same  time,  N.C.'s  1978  nonwhite  female  age-adjusted 
rate  remained  50%  above  the  white  female  rate  with  excesses 
in  most  major  causes.   Recent  trends  reveal  substantial 
increases  in  lung  cancer  and  suicide  with  smaller  increases 
in  pancreatic  cancer  and  nephr i t i s/nephros i s.   And  with 
higher  rates,  N.C.'s  nonwhite  females  are  lagging  behind 
their  U.S.  counterparts  in  red  :ing  death  from  hypertension, 
arteriosclerosis,  diabetes  and  non-motor-vehicle  accidents. 

Except  for  a  static  nonwhite  male  rate  in  the  Southern  Piedmont,  Table  2  reveals 
that  all  HSA's  have  shared  in  the  recent  mortality  declines  of  all  four  race-sex 
groups,  especially  nonwhite  females,  and  these  declines  are  reducing  the  gaps  between 
whites  and  nonwhites  of  both  sexes.   In  contrast,  greater  downturns  in  female  mortality 
have  widened  the  gaps  between  N.C.  males  and  females  of  both  races.   These  trends 
are   observed  in  the  race  and  sex  ratios  of  Table  k   where  it  is  also  shown  that  race 
differences  are  greater  for  females,  sex  differences  are  greater  for  whites  and  sex 
differences  are  greater  than  race  differences.    Based  on  the  rates  of  Table  2,  this 
is  generally  true  in  all  HSA's.   The  1978  race  and  sex  ratios  for  HSA's  also  reveal  that 

-  race  differences  are  greater, in  the  three  westernmost  HSA's; 

-  sex  r  'fferences  are  highest  in  the  Capital  HSA. 

The  decline  in  mortality  from  stroke  and  heart  disease  in  North  Carolina  reflects 
a  nationwide  trend.   The  reasons  for  this  decline  are  unclear;  a  number  of  primary 
and  secondary  prevention  factors  have  been  cited  including  improved  coronary  care 
techniques,  changes  in  diet  and  increased  exercise.   While  there  is  still  debate  on 
the  role  factors  such  as  these  may  have  played,  there  is  little  disagreement  that  the 
improved  detection  and  treatment  of  hypertension  and  reduced  cigarette  smoking  have 
played  important  roles.   In  spite  of  these  declines,  cardiovascular  diseases  remain 
the  leading  causes  of  death  in  both  North  Carolina  and  the  nation.   Obviously,  there 
remains  a  great  deal  of  preventive  medicine  work  to  be  done. 


Table  k 

Race  and  Sex  Ratios: 
Age-adjusted  Mortality  Rates 

North  Carolina,  1973  and  1978 
Ratio  of  Nonwhite     Ratio  of  Male  to 


to  Wh 

te  Rates 

Fema 

e  Rates 

Year 

Males 

Females 

Whites 

Nonwhi  tes 

1973 

l.'<3 

1.65 

1.98 

1.71 

1978 

1.1.1 

1.51 

2.03 

1.90 

Some  other  comments  are  that  (l)  unadjusted  rates  are  certainly  valid  and  prefer- 
able indicators  for  allocating  health  manpower,  facilities,  supplies,  etc.,  but  in 
assessing  mortality  "risk,"  adjustment  for  confounding  factors  such  as  age  is  the  only 
way  to  go;  (2)  all  mortality  rates  are  subject  to  spatial  differences  or  temporal 
changes  in  certification  practice  and/or  accuracy  of  diagnoses  and  (3)  as  always,  the 
accuracy  of  rates  examined  here  is  also  contingent  upon  the  accuracy  of  population 
bases. 

In  summary,  it  has  been  demonstrated  empirically  that  both  race  and  sex, 
especially  sex,  are  differentiating  factors  in  mortality  risk,  even  more  so  in  North 
Carolina  than  nationwide,  and  North  Carolina's  sex  differential  is  widening.   The  age- 
adjusted  data  also  underscore  the  need  for  expanded  initiatives  in  the  area  of  accidents, 
both  motor  vehicle  and  other  types. 


REFERENCES 

(1)  North  Carolina  Department  of  Human  Resources,  Division  of  Health  Services, 

Administrative  Services  Section,  Public  Health  Statistics  Branch.   Leading 
Causes  of  Mortality,  North  Carolina  Vital  Statistics  1978,  Volume  2. 
Raleigh,  October  1979- 

(2)  U.S.  Department  of  Health,  Education,  and  Welfare,  Public  Health  Service.   Monthly 

Vital  Statistics  Report:   Advance  Report  Final  Mortality  Statistics,  1977, 
from  the  National  Center  for  Health  Statistics.   Vol.  28,  No.  1.   Hyattsvi lie, 
Maryland,  May  11,  1979- 


Rates  for  this  study  were  produced  by  adjustment  programs  developed 
in  the  State  Center  for  Health  Statistics.   Available  to  other  users, 
these  programs  use  the  direct  method  to  adjust  for  all  or  any  combi- 
nation  of  age,  race  and  sex. 


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