UC-NRLF ON, >- LIBRARY OF THE UNIVERSITY OF CALIFORNIA. Class BIOLOGY LIBRARY G WORKS BY T. MITCHELL PRUDDEN., M.D. DIRECTOR OF THE PHYSIOLOGICAL AND PATHOLOGICAL LABORATORY OF THE ALUMNI ASSOCIATION OF THE COLLEGE OF PHYSICIANS AND SURGEONS, NEW YORK A Manual of Practical Normal Histology. i6mo, cloth $i 25 44 A handy book for students. Very practical and very intelligible." — The American Specialist. 41 We are happy to find that a really valuable addition has been made to literature. • • . The author is evidently a master of his craft, and frlly understands the practical details. We are surprised at the amount of information put in such small compass." — Boston Medical and Surgical Journal, The Story of the Bacteria. i6mo, cloth . 75 cents 44 It is written in clear, concise sentences, without any effort at display, and can be read with profit and enjoyed by any intelligent reader as well as by the most scientific physician." — Chicago Interocean. Dust and Its Dangers. Uniform with " The Story of the Bacteria." Illustrated .... 75 cents 41 It is in one sense an alarmist book, but it alarms in a proper direction, and performs a service that cannot be overvalued. . . . The book is to be warmly commended, and should attract general attention." • — Boston Gazette. Drinking-Water and Ice Supplies, and Their Rela- tions to Health and Disease. i6mo, cloth, illustrated, 75 cents. ** Dr. Prudden's little book is crammed with information — practical information — which to thousands of families would be worth, if duly read and heeded, far more than money " — Hartford Times. G. P. PUTNAM'S SONS, PUBLISHERS, NEW YORK AND LONDON. DUST AND ITS DANGERS BY T. MITCHELL PRUDDEN, M.D. \ t AUTHOR OF 11A MANUAL OK PRACTICAL NORMAL HISTOLOGY, THB STORY OF THE BACTERIA," ETC. G. P. PUTNAM'S SONS NEW YORK LONDON 27 West Twenty-third Street 24 Bedford Street. Strand Ube •fcmcfeerbocfeec press 1904 T7 BIOLOGY UBRARY G COPYRIGHT 1890 BY T. MITCHELL PRUDDEN, M.E* Ubc Iknfcfcetbochcr press, flew PREFACE. little book has been written with the J_ purpose of informing people, in simple language, what the real danger is of acquiring serious disease — especially consumption — by means of dust-laden air, arid how this danger may be avoided. It is an unpleasant subject ; but it is one which every one must know something about if he would avoid such physical ills as are much more serious drawbacks to comfortable living than are the temporary mental disquietudes which this book is designed to inflict upon its readers. T. M. P. 131233 CONTENTS CHAPTER PAGE I. — THE NATURE OF DUST IN GENERAL . . i II. — THE LIVING ELEMENTS OF DUST ; WHAT THEY ARE AND WHERE THEY COME FROM .... 7 III. — How THE LIVING ELEMENTS OF DUST ARE STUDIED . n IV. — THE MICRO-ORGANISMS OF OUT-OF-DOORS DUST . 20 V. — THE MICRO-ORGANISMS OF IN-DOORS DUST . . 27 VI. — THE SAFEGUARDS OF THE BODY AGAINST INHALED DUST . . . • . » . « . 36 VII. — THE REAL SIGNIFICANCE OF DUST IN ITS RELATION TO DISEASE . . . _ . . •* . '.- « . 50 VIII. — CONSUMPTION AND THE WAYS IN WHICH IT is SPREAD BY DUST . . . . . . . . .58 IX. — DUST-DANGERS OUT-OF-DOORS AND IN PRIVATE HOUSES, WITH SUGGESTIONS FOR THEIR AVOIDANCE 74 X. — DUST-DANGERS IN PUBLIC BUILDINGS AND PUBLIC CONVEYANCES . . _. . . . . . .80 XI. — SOME OBJECTIONS, PROTESTS, AND QUERIES AN- SWERED 87 XII. — SUMMARY AND CONCLUSION 99 INDEX ........... 105 vii ILLUSTRATIONS. PAGE PLATE I. — Different forms of micro-organisms. To face . . 8 FIG. i — A. — A single " colony" of rod-shaped bacteria (bacilli) growing on a plate of nutrient gelatine. The actual diameter of this colony was about one fourth of an inch. B. — A cluster of the bacilli taken from the colony and highly magnified . . . . . . . .13 FIG. 2. — The " plate method " of air analysis . . . .17 PLATE II. — Colonies of micro-organisms growing on dust particles. To preced,: . ... . . . .21 PLATE III. — Showing results of " plate analyses" of the air of different places in New York. To face . . ; .24 PLATE IV. — Effect of sweeping on the number of micro-organ- isms in the air. To face ...... 32 FIG. 3. — Ciliated cells from the large air-tubes of the human lungs, seen from the side ...... 39 FIG. 4. — Pigmentation of the lung from inhaled dust . . 44 FIG. 5. — Dust filters in the lung — deeply pigmented . . .47 FIG. 6. — Lymph filters (lymph-glands) at the root of the lung, the seat of local and healed tuberculosis .... 69 DUST AND ITS DANGERS; CHAPTER I. THE NATURE OF DUST IN GENERAL. IF this were not a practical age, and if the title on the back of this little book did not fairly promise a reasonably practical theme, it might be thought incumbent on the writer, in this age of nice analysis of very small things, to be explicit at the outset as to what he does or does not mean when he says dust. For af- ter all, when we think of it, there are a good many kinds of dust. There is, for example, molecular dust, which swaying ever in space catches and breaks the sunbeams, giving us now the deep blue of full day and again the gorgeous colors of the earlier and later hours. DUST AND ITS DANGERS. There are those masses of " water dust " which we call clouds and fogs and steam. There is the scriptural dust, bearing, according to ortho- dox traditions, such a close relationship to the origin and endings of mundane existence. Col- loquially, there is a form of "dust" too which to win many a mortal seems to forget both his origin and his destiny, yielding at last that dust which he has won to be himself resolved into that to which he was foreordained. But if we plant our standard on Webster's first choice, and let dust be for us " Fine dry particles of earth or other matter so attenuated that it maybe raised and wafted by the wind," we shall not be apt to stray too far from the practical, nor fall foul of either primordial or ecclesiastical or pecuniary dust. Simple, common, omnipresent every-day dust then, — the bane of the tidy housekeeper, the torment of the cleanly citizen who goes upon the streets in ill-kept towns, wafted upon every breeze without, stirred by every footfall within, — this is the humble but significant subject to which, not without reason, it is believed, these pages are devoted. DUST AND ITS DANGERS. The dust particles of the air may be roughly grouped in two classes — first, those larger bodies which are readily visible in-doors or out-doors, and second, the smaller particles which are usu- ally only seen when strongly illuminated. The coarser particles of dust, such as are usually swept into our faces whenever we go upon the streets in New York in dry and windy weather, consist largely of small frag- ments of sand, broken fibres of plants, pollen, fine hairs, the pulverized excreta of various domestic animals, ashes, fibres of clothing and other fabrics, particles of lime or plaster or soot, parts of seeds of plants, masses and clus- ters of various kinds of micro-organisms, and other partially ground up materials of kinds too numerous to mention. The finer dust particles, whose presence, when in considerable quantities, we may be aware of by the choking sensation which they cause when breathed in, even though we do not see them, are most plainly visible as the so-called " motes in the sunbeam," when sunlight streams into more or less darkened places. These are very light and consist of fragments 4 DUST AND ITS DANGERS. of fine vegetable or animal fibres, such as cot- ton or woollen or other light material, and of the greatest variety of micro-organisms, either singly or in masses, such as bacteria and mould spores. Furthermore, these micro-organisms are very apt to be found clinging singly or in clusters to the larger or smaller inorganic particles of one kind or another which usually make up the bulk of visible or invisible dust in inhabited regions. It is not necessary for our purposes here to enter in detail into those conditions of soil and climate and human occupation which favor the presence of dust in the air. That dry air and dry-ground surfaces and winds favor the distri- bution of the fine particles which we call dust, and that still air and moist ground tend to hold it in check, are facts which every one's observa- tion teaches. It is well known that there are certain occu- pations which confine persons to closed rooms or places in which dust particles of one kind or another are very abundant. Thus day after day persons confined in air charged with coal- dust or stone-dust or metallic-dust or cotton- DUST AND ITS DANGERS. 5 or woollen-dust or tobacco-dust, etc., are apt to become victims of more or less well marked pulmonary affections, which are to be found fully described in systematic treatises among the so-called " diseases of occupation." It is not with these exceptional places nor with the special conditions which belong to them that we are now concerned, but with the conditions under which both well and sick peo- ple of all classes are placed, especially in cities, and more particularly when in-doors. Nor shall we occupy ourselves here to any consid- erable extent with the inorganic ingredients of dust, but more especially with those living components called micro-organisms, be they either bacteria or moulds. I purpose, in the first place, drawing upon the results of various old and recent studies, to indicate the sources of the living germs which form such an important part of the dust of in- habited regions, the ways in which they get disseminated in the air, and their general de- portment as they are driven hither and thither by the winds, sway poised in the still air of quiet places, or settle slowly to the ground. DUST AND ITS DANGERS. I purpose then to show the difference of conditions which prevail, in-doors and out, and the significance of these conditions in the problems of ventilation and cleanliness. I shall then give the results of a series of studies of the atmospheric micro-organisms in various places, and consider the relationship of these aerial germs to some common forms of disease. Finally, I shall suggest some of the measures which must be adopted, both by the public au- thorities and private persons, if both out-of- doors and in-doors we are to have the privi- lege of breathing clean and wholesome air. I shall not, except incidentally, touch upon the ordinary problems of ventilation or the numer- ous ways in which by the accumulation of the products of respiration and exhalation the air of inhabited rooms may become an active source of discomfort and ill-health, because the means by which these evils may be avoided are well known and are fully explained under the heading of ventilation in text-books and treatises on hygiene. CHAPTER II. THE LIVING ELEMENTS OF DUST J WHAT THEY ARE AND WHERE THEY COME FROM. ALL those forms of minute vegetable life which swarm in myriads almost every- where upon the earth's surface are called in general micro-organisms or germs. Among these there are three prominent forms which are called bacteria, yeasts, and moulds (see Plate I.). Among these the bacteria are by far the most important. These tiny organisms are for the most part so very small that many thousands or millions of them clustered closely together would not make a mass larger than the head of a pin. Some of them are round or ovoidal, some rod-like, some spiral (see Plate I. Fig. 3). Most of them are harmless to man, and serve a very important purpose in the economy of nature in tearing asunder 7 8 DUST AND ITS DANGERS. dead and worn-out organic material and setting it free in suitable condition for the building up of new forms of life. A few species of bacteria, however, are capable of causing some of the most wide-spread and most dreaded of human diseases. The writer has in another book T described in simple and untechnical manner the various forms of bacteria and their relationship to man, and to this he must refer the reader for fur- ther details as to their nature and life history. The moist surfaces of decaying vegetables and plants and the bodies of animals, all solid excreta of the bodies of men and animals, human sputum, stagnant water, the surface of the soil in inhabited regions, etc., afford fertile fields of growth for myriads of micro-organisms of one kind or another. But we should always remember that bacte- ria do not become detached from the surfaces or materials on which they grow or are lodged while these are in the moist condition. Even the air sweeping in strong currents through sewers whose watery contents and moist walls 1 " The Story of the Bacteria." DUST AND ITS 'DANGERS. may be swarming with bacteria does not be-, come charged with these. The bacteria, singly or in masses, free, or attached to other par- ticles of one kind or another, must first be dried and then the clusters more or less pul- verized or ground up, before they are swept away and suspended as a part of the dust in the air. There are indeed certain moulds — the green mould, for example, which is so common on various moist articles of food — which form very light and not easily moistened spores (see Plate I. Fig. i), these may be readily brushed or blown off and mingle with the dust under almost all conditions. All sorts of bacteria-laden material then, when dry and ground up as it so readily is by the varied movements of men and animals out-doors and in-doors, may become a part of the floating dust. These dry minute germs, some of which are alive and some dead, com- port themselves in the air just as lifeless dust particles of any other kind do. They are wholly inert, and are driven hither and thither by air currents, now in clouds or masses of al- 10 DUST AND ITS DANGERS. most stifling density, and again in very small numbers, collecting in whirls and eddies, and finally, always sooner or later, settling down to the lowest available resting-place, as soon as the buoyancy of air currents gives way to the ever acting attraction of gravitation. Since the bacteria of dust are very apt to be in little groups or clusters or to cling to other dust par- ticles, most of them readily settle, so that a very considerable part, in fact, of the finer dust — the " motes in the sunbeam " — is not made up of bacteria or germs but of other forms of lifeless matter. CHAPTER III. HOW THE LIVING ELEMENTS OF DUST ARE STUDIED. HOW do we find out how many living germs there are and of what kinds in a given volume of air ? It will suffice for our purposes here to say that the bacteria are so extremely small that the search for them as they occur in nature is ordinarily of little avail by the simple use of the microscope. We have recourse in such studies to what is called the " culture method." ' By this method, instead of bringing a portion of fluid or of the air in which we wish to seek for bacteria di- rectly under the microscope, we mix a small portion of the fluid or air with some material which serves as food for the germs, and on or in which they will readily grow. 1 See " The Story of the Bacteria." II 12 DUST AND ITS DANGERS. This food medium usually contains some form of gelatine. The gelatinized material is usually melted when the planting is being done, and when it cools the bacteria are held firmly in the position in which they lodged when they were put in. The bacteria placed under these conditions multiply with such great rapidity that usually in a short time the progeny of a single living germ will have accumulated to such a degree right in the spot where the germ lodged that the mass of them, which we call a " col- ony " will be readily visible to the naked eye, or under a low power of the microscope (see Fig. i). Now since we can readily see the mass of bacteria which has grown where only a single germ had lodged we have only to count the colonies to know how many living bacteria were present in the volume of air or fluid which we have tested. We can now, futhermore, subject the little colonies which form our bacterial crop to a va- riety of examinations and tests, and make out what kinds there are, and further learn their effects upon man or animals. DUST AND ITS DANGERS. Now a good many plans have been devised for finding out how many living germs are present in a given volume of dusty air. We A FIG. I. Fig. i. A — A single "colony" of rod-shaped bacteria (Bacilli) growing on a plate of nutrient gelatine. The actual diameter of this colony was about one-fourth of an inch. B — A cluster of the bacilli taken from the colony and highly magnified. may force a given volume of the air through a tube which has been plugged with cotton-bat- ting previously heated so hot as to kill any 14 DUST AND ITS DANGERS. germs which by chance have been upon it. The cotton if properly packed in the tube will catch and hold entangled in its meshes all the dust particles no matter how small, and with these all the bacteria which were in the air which we force through the tube. If now we carefully pull out the cotton plug with a pair of perfectly clean forceps, and thoroughly rinse it off in a small clean flat dish containing our bacterial food — which we call " the culture me- dium,"— the germs will be distributed through the medium, and we cover the dish and set it aside in a warm place and let it stand until each living germ has grown and multiplied till it forms a visible colony. Now we count the col- onies, and the number represents the number of living germs which were present in the whole volume of air which we forced through the cot- ton plug. There are of course many details and precautions against error which must be observed, but this brief description will suffice for our purposes here. It has been found in practice, however, that it is better to use fine sand than cotton in the tubes to catch the germs, since this is more DUST AND ITS DANGERS. 1 5 easily handled and is equally efficient as a filter. We plant the sand together with the dust which it has caught in the melted culture- medium, allow it to cool and then stand for a few days, and when the colonies are grown they are easily distinguished from the sand particles by their shape, color, etc., and can be readily counted. Or, we may use granulated sugar for a filter, which finally dissolves in the culture- medium, leaving the bacteria to grow in due time. This may be called the " filtration method " of air analysis. As it requires an accurate and somewhat complex and cumbersome apparatus to force or draw the air through either the cotton or sand filter, another and simpler method is often resorted to, which, though in some re- spects less accurate, still gives very useful results when we wish simply to compare the germ ingredients of the air in one place with those in another under similar general condi- tions. This simpler method consists in pouring into a series of perfectly clean shallow glass dishes a thin layer of the warm gelatinous culture- 1 6 DUST AND ITS DANGERS. medium and allowing it to solidify by cooling. This gives a smooth, moist, somewhat adhesive surface of equal size in each of the dishes, which are immediately protected from any chance contamination by closely-fitting glass covers. This mode of air analysis depends upon the fact which we have mentioned above, and which everybody is familiar with, namely, that all dust particles, light or heavy, in quiet places, slowly but surely settle towards the ground. If now we set one of our covered dishes in a still place and take off the cover, the dust particles, the inorganic as well as the living, will settle on to this moist nutrient surface. With the inorganic components of the dust, the multifarious shreds and patches of one thing or another, this is the end of the matter. But as the living dust particles touch the surface, like Antaeus, they find their abeyant vigor quickly renewed, and forthwith commence to multiply and inherit their little new-found earth. Now, suppose we leave our dishes un- covered and exposed to the falling dust for, say five minutes ; suppose further that the sur- DUST AND ITS DANGERS. face of the culture-medium is three square inches in size, it will be readily seen that by the exposure of dishes of the same size for the FIG. 2. — THE "PLATE METHOD" OF AIR ANALYSIS. The cut shows the appearance of the flat, shallow dish, the bottom of which was covered with nutrient gelatin, and when this had cooled and solidified, was uncovered and exposed to the air in a moderately clean place for five minutes. It was then allowed to stand in a warm place for four days. Immediately after the exposure of the gelatin to the air nothing whatsoever was visible on its surface. But within a few hours tiny spots appeared which grew larger, some more rapidly than others. These " colonies," at the end of four days, when the draw- ing was made, vary considerably in size and appearance, because they are mostly made up of different species of germs. Each colony con- sists of thousands of germs (see Fig. I, A), which have grown on the spot where the lone ancestor fell from the air and stuck fast during the five minutes exposure of the gelatin. same time to the air of different places, we can, by comparing the number of bacterial 1 8 DUST AND ITS DANGERS. colonies which develop on the surfaces, get at least an approximate idea of the relative num- ber of suspended bacteria slowly settling in the air of the different places (see Fig. 2). We cannot, of course, by this method say how many germs were present in a given vol- ume of air, as we can by the more elaborate and accurate method given above, and there are many minor sources of error. For exam- ple, the mould spores are so very light and buoyant that they fall but slowly, so that we may altogether miss many of them, and the same may be true of some of the lighter bac- teria. Moreover, even very slight upward air currents may interfere with the settling of the germs, and in windy places this method is of little use. But on the whole, if similar condi- tions are maintained in the different analyses, comparative results may be obtained in this way which are of much value, as we shall pres- ently see. This, which we will call the "plate-method," enables us to get a general notion of the bac- terial contents of the air in various places under conditions which would render the use of the DUST AND ITS DANGERS. more accurate and cumbersome apparatus dif- ficult or impracticable. We can go about with our innocent-looking little case of glass boxes, partly filled with nutrient gelatin, as does the amateur photographer with his detective cam- era ; though instead of " pulling the string, touching the button, and leaving the rest to the manufacturer," we raise the cover, take the time, and let Nature do the rest. We are now ready to look at the results of a series of so-called biological analyses of the air of various places. We mean by biological analysis of air, in distinction from the chemical, an analysis which has for its object the deter- mination of the number or character, or both, of the living germs, or micro-organisms which may be suspended in it. CHAPTER IV. THE MICRO-ORGANISMS OF OUT-OF-DOORS DUST. WE must be on our guard in looking at the results of such analyses as those now to be described against hasty inferences as to their significance. It would be a grave mistake to suppose that living germs in the air are necessarily harmful to human beings, and to infer that air found to habitually con- tain few bacteria is necessarily more salubrious than that which contains more. For the pres- ent, then, let us look upon the results of these analyses simply from the biological standpoint, and, if possible, place ourselves in the attitude of botanists studying the flora of the atmos- phere, not of physiologists concerned with the relationship of these tiny plants to man. This we shall come to by and by when we have ac- cumulated enough facts to justify such infer- ences as may urge themselves upon us. 20 EXPLANATION OF PLATE II. This cut shows the appearances which are presented, after the germs have grown, by particles of sand and shreds of vegetable fibre to which single germs were clinging when they settled on to the un- covered gelatin plate. In this case the drawing was made five days after the exposure of the plate to the air of a dusty street. The largest of these colonies were barely visible to the naked eye. I. — Shows a particle of sand completely surrounded by the colony or mass of bacteria which has grown from a single germ which was clinging to the minute sand particle as it settled with the dust. 2. — Shows a tiny shred of wood to which five different germs were attached as it settled on to the exposed plate. We should probably have searched in vain, even with a powerful microscope, for the single germs clinging to it at the time this wooden dust particle planted itself on the surface of the gelatin. But now the larger colonies are visible even to the naked eye. We know that they grew from different species of germs because under a moderate magnifying power they present such markedly different appearances. 3. — Shows a minute sliver to which four different forms of germs were clinging as it fell. DUST AND ITS DANGERS. 21 From the enormous number of bacteria and moulds, which are present everywhere in in- habited regions where the conditions are suit- able for their growth, it might be imagined that in dry weather the number of atmospheric germs in the dust out-of-doors would be very great. But this is not usually the case, even in large and populous towns. Here and there along the streets, where these are filthy and almost never properly cleaned, as in New York, or where the wind whirls around the corners of buildings, forming air eddies, the micro-organisms are often present in very large numbers, so that one in passing about the town is apt here and there to encounter veritable germ-showers. But on the whole, almost everywhere out-of-doors, except in dangerously filthy cities, the large volumes of air, which are more or less constantly passing, so largely di- lute the local germ-dusty air that the actual number of micro-organisms in a given volume, say a cubic foot, is on the average very small, and usually insignificant. When the ground is wet and air currents moderate, the number of germs is still further diminished. 22 DUST AND ITS DANGERS. It is very difficult to fix upon any definite number of living micro-organisms in the out- of-doors air which can be regarded as the usual or normal number, because the number varies so extremely under different conditions. Thus on high mountains or deserts and on the sea the unconfined air is practically free from micro-organisms. In the winter months, when snow is on the ground, during rain storms, and when the air is still, the number may be very small. On the other hand, a high wind blowing across a region rich in dry and pulverized germ-laden material, will for a time disseminate large numbers of micro-organisms ; but at the same time it tends, by the dilution which it affords, and by carrying them off to other re- gions, to speedily reduce the numbers in any given place. A rainfall, to a certain extent, tends to free the air of its germs by washing them down, while during a snowstorm many are caught in the snow crystals as they form. In wet weather mould-spores tend to pre- dominate, partly because they then grow readily and partly because they are very light, and not as easily wetted and held down as are the bacteria. DUST AND ITS DANGERS. 2$ The analysis of out-of-doors air shows, as might be expected, a great deal of variation in the number of living germs present in a given volume. Ten litres, which is about 600 cubic inches (that is a volume equal to a cube of about 8 inches square), is the volume of air usually taken as a sample for purposes of analysis. Carnelly found in still out-of-doors air, in the town of Dundee, in Scotland, as the result of 14 analyses, an average of less than 10 bacteria in 10 litres of air, while in another place there were over 1 70 in the same volume. Tucker found the air in Boston, from a secluded place, but in the immediate vicinity of its traffic, during the mild but rather windy weather in November, December, and January, with no snow on the ground, to contain on the average of 56 analyses, less than 20 bacteria to 10 litres. In an open court at the Hygienic Institute in Berlin, Petri found, as a rule, equally small numbers. The average of 1 3 analyses, made in March and April, 1 890, of the air from the yard of the College of Physicians and Surgeons, in New 24 DUST AND ITS DANGERS. York, at a place as far from the streets as pos- sible, and about 25 feet from the ground, showed the number of bacteria in 10 litres to be 56 and of moulds 4. Analyses, during the same period, of the air of the streets in New York, from various parts of the town,1 showed the average number of bacteria in 10 litres to be 376, and of moulds 6. These analyses of street air were made under ordinary conditions, at such times of the day 'as the air appeared to be at its best. If an analysis is made of the air in the dust clouds which sweep along the ill-kept streets of a city like New York or which blows from the street sweepers as they pass along the unwatered thoroughfares into the houses or over the unwary passer-by, the numbers of germs to the litre is startling. Let us look at a graphic record of the rela- tive number of bacteria in various places, made by the plate method already described. Plate III. shows the result of a series of comparative analyses made in this way in var- 1 This was at a time when the so-called politicians were juggling with the Street Cleaning Department while the streets were largely left to take care of themselves. PLATE III. — SHOWING RESULTS OF " PLATE ANALYSES " OF THE AIR OF DIFFERENT PLACES IN NEW YORK. (See explanation in the text.) DUST AND ITS DANGERS. 2$ ious places in New York on a clear, dry, mod- erately breezy day, in April, 1890. Each one of the spots represents a colony of bacteria, which has grown from the single germ which settled on to the moist surface during the five minutes exposure to the air. 1. Ball Ground, Central Park. — A mod- erate westerly wind bringing dust over from the Eighth Avenue and its cross streets. 2. Union Square. — At the edge of the fountain basin. 3. The library of a private house not far from 34th Street and Broadway. 4. A large retail dry-goods store on one of the uptown cross streets near Broadway, during a busy hour of the day, when there was much stir and bustle. 5. Railing of the small park at Broadway and 35th Street. 6. A cross street through which the carts of the Street-Cleaning Department were passing collecting the dry heaps of street dirt. If we translate into numbers the appearances of the cultures shown in Plate III., we find that during five minutes the number of living germs 26 DUST AND ITS DANGERS. which settled from the floating dust on to the bottom of a round dish about 3f inches in diameter in different places in New York was as follows : 1. Central Park. — Dust blowing from an adjacent street, 499. 2. Union Square, 214. 3. Private house, 34. 4. Large retail dry goods store, 1 99. 5. Broadway and 35th Street, 941. 6. Street in the process of being cleaned, by the Street-Cleaning Department, 5,810. A sufficient explanation of the number of germs in the air at the lower part of Central Park is found in the westerly wind and the ex- tremely filthy condition of the streets on the windward side. The result of the analysis shown in fig. 6, needs no lengthy comment. That as many living germs as of colonies which are here seen growing should be float- ing in the air and liable to be breathed in by any unfortunate passer-by within five minutes, is evidence enough of the filthiness of the present practices of so-called street-cleaning in New York, As to its danger, more by and by. CHAPTER V. THE MICRO-ORGANISMS OF IN-DOORS DUST. WHEN we consider the comportment of dust particles in closed rooms, we see at once that the great renovating and cleansing agency which is so efficient out-of-doors is, ex- cept on special occasions, absent, namely, the winds and strong air currents and the more or less frequent and prolonged wettings. Once in a closed room dust is very apt, as every housekeeper knows, to stay there, unless special means are resorted to to get rid of it. But although the dust remains in the room, those heavier parts of it which contain most of the bacteria gradually sink to the lowest available levels, floors, shelves, furniture, etc., so that it has been found that the still air of a room may almost completely free itself from micro-organisms, except some of the lighter 27 28 DUST AND ITS DANGERS. mould spores, within one or two hours. Of course violent currents of air, walking about, etc., interfere with the very complete subsi- dence of the bacteria-laden dust particles. Now it might be supposed that the frequent renewal of the air of a room by such a system of ventilation as would be effective in keeping its gaseous ingredients pure would also suffice to rapidly carry off dust particles, and bacteria as well. But a long series of most carefully conducted experiments by Stein has shown that this is not the case. Even when the in- troduction of fresh air is pushed to the com- plete renewal of the air three times an hour, the number of suspended micro-organisms floating in the air is scarcely more diminished than they would be by settling in still air. Stein found that only when the ventilation was carried to the degree of inducing marked and disagreeable draughts in the room was there a rapid diminution in the number of micro-organisms which had been diffused arti- ficially through the air for the purposes of the test. Of course opening of the windows and allowing large bodies of air to blow through ^ \ *» " " T ^V S ^ jr T« A I rrY ) XOf Dl DUST AND ITS DANGERS. 29 the room, quickly resulted in sweeping away a large proportion of the suspended micro-or- ganisms. But this observer also found that even very strong air currents were not able, when sweeping over woollen and other fabrics, carpets, hangings, etc., which had been be- strewn with bacteria-laden dust, to free the germs to any considerable extent from these. The strong air currents carried off the sus- pended particles, but those which had settled on to the fabrics and floors were but little affected. The practical bearings of this ob- servation we shall see by and by. When we consider the constant tendency of dust particles to settle as soon as they find themselves in quiet places out of strong air currents, and the fact that even ordinarily efficient systems of ventilation do not carry off any considerable proportion of the dust par- ticles from closed still rooms, we are led to the rather startling conclusion that the ordinary living-rooms, even though they be well ven- tilated, are actually dust and bacteria reposi- tories, and that when by a system of forced ventilation we cause large volumes of dust- 30 DUST AND ITS DANGERS. laden air from out-of-doors to pass through them we are actually, so far as micro-organisms are concerned, cleansing the air and sending it out much freer from germs than when it en- tered, these having slowly settled as the air made its way from the entrance to the exit of the ventilating openings. The same of course applies, though in a less striking way, to the so-called natural mode of ventilation — that is a ventilation system which has for its exit a warm air-shaft or chimney, and " trusts to luck " for channels of air entrance through loose joints in windows, doors, and walls. Now, although in rooms through which for purposes of ventilation large volumes of dusty out-of-doors air are pumped, day and night, there will be in the aggregate a considerable accumulation of more or less bacteria-laden dust, it is, after all, the ground-up dirt which we bring in from the streets upon our shoes and garments, and the accumulations of waste material, which in dwelling-houses and places of assembly are so abundant, which furnish the larger proportion of the bacterial ingredients of in-doors air. The marked difference be- 3 DUST AND ITS DANGERS. 31 tween the atmospheric dust in closed rooms and that out-of-doors is that in the former there is no spontaneous mode of purification of the air except that of settling, and that the settled more or less bacteria-laden dust is liable to frequent stirring-up by the ordinary movements of people, while out-of-doors the bacteria-laden air is constantly being swept off by the wind. The effect of stirring about in rooms in which micro-organisms are present is shown by the analyses of Tucker in the wards of the Boston City Hospital. He found that about midnight after the wards had been quiet for a few hours, the number of living bacteria in 10 litres of air ranged from o to 13, while the number of mould spores ranged from o to 4. The air had practically freed itself from germs, by settling to floors and beds. He found that in a long series of hourly determinations in various wards at all hours of the day, the average number of bacteria in 10 litres of air was about 26 and of moulds about 12, the number of bacteria rang- ing from i to 477; of moulds from o to 227. The germs were more abundant in the air in 32 DUST AND ITS DANGERS. the forenoon when the beds were being made and the wards cleaned and put in order. He found that sweeping nearly doubled the number of germs in the air already disturbed by the routine work in the wards in the morning, and considering the number of germs in the 10 litres of air in the early morning before the wards were astir as the minimum — i — the general cleaning routine work and sweepi-ng were capable of increasing the number, on the average, seventy times. The difference in the number of living germs floating in the air of a room before and after sweeping, is graphically shown in Plate IV. The room in which these analyses were made, was a most carefully kept hospital ward in New York, in which were about 25 persons. Be- fore the sweeping, when quiet had prevailed for about an hour, the number of living germs which settled on to the dish, 3^ inches in di- ameter, was 12 (see Plate IV., Fig. i). Im- mediately after sweeping, the number which settled on to a similar surface, was 226 (see Plate IV., Fig. 2). Very much larger differ- ences are often found in the number of germs DUST AND ITS DANGERS. 33 in the air before and after sweeping, if the rooms are not frequently carefully and properly swept and dusted. Thus in a carpeted living- room in a tenement on loth Avenue, 75 bacteria and i mould settled on to the surface of the exposed plate in five minutes before sweeping. When the room was still, immediately after sweeping, a similar experiment showed over 2,700 bacteria and 6 moulds. Carnelly found in hospital wards in Dundee in the afternoons from 10 to 20 bacteria in 10 litres of air. Neumann found after sweeping from 80 to 140 bacteria, and later in the day from 4 to 10 in 10 litres. On the other hand, Carnelly found in houses which are denomin- ated clean, 180 bacteria in 10 litres of air, while in very dirty houses there were over 900. In dirty school-rooms, with the so-called natural ventilation, he found in the same vol- ume of air nearly, 2,000 living bacteria, while in mechanically ventilated schools there were from 30 to 300. The writer has found as the result of 23 analyses of the air of various laboratories, lecture-rooms, and hall-ways, at the College of \ 34 DUST AND ITS DANGERS. Physicians and Surgeons in New York, under the ordinary conditions of occupation by con- siderable numbers of students during March and April, 1890, that the average number of bacteria in 10 litres was 11 and of moulds 14. The average number of germs in various hospitals and dispensaries in New York during the same period in 10 litres of air, (19 analyses) was bacteria 127, moulds 25. We thus see that the number of living germs in a given volume of in-doors air varies greatly in different places and under different con- ditions. We see that the temporary freeing of the in-doors air from germs can be accomplished by simply closing the rooms and keeping the contained air still when within one or two hours nearly all dust and most of the bacteria will have settled to the lowest resting-place. Whether the air shall be permanently rid of its living or inert dust particles or not, will of course depend upon the measures which are resorted to in the familiar performances of sweeping and dusting, of which more by and by. A good many of these facts which have been just set down in regard to dust, are embodied DUST AND ITS DANGERS. 35 in the lore of the intelligent house-keeper, scientific studies having simply given precision to common beliefs and revealed certain quali- ties in dust, which may possibly render it of greater significence than an annoying and an omnipresent form of dirt. CHAPTER VI. THE SAFEGUARDS OF THE BODY AGAINST IN- HALED DUST. HAVING now gathered together a con- siderable number of facts about the distribution in the air of dust particles and among them of living germs, we are ready to consider their significance — if they have any — to human beings, who must live in and breathe this more or less dust-laden air. The average amount of air which a healthy grown person takes in at each breath has been estimated to be about one half a litre (about 30 cubic inches). We have seen from our various analyses of the air of different places in and about New York, under ordinarily favor- able conditions, that the number of living germs in 10 litres of air varies from 1 1 to 376. So that basing our estimate upon these studies 36 DUST AND ITS DANGERS. 37 of the air in this city, with every twenty breaths one may take into his body, depending upon where he is all the way from u to 376 living micro-organisms, together with a variable amount of inorganic dust. The number of living germs which the New York citizen is liable to be forced to take into his body, when the streets are dry and the wind blowing, or when the dry filth is being stirred up by the diabolically careless proceed- ures of the present street-cleaning fiends, it would be a thankless task to tell. Now it has been learned, not only from com- mon experience but from long series of careful experiments, that the solid particles which we breathe in with the air either through the nose or mouth do not come out with the expired air, but are retained on the moist surface upon which the air impinges going in and coming out. These foreign particles floating in the inspired air are caught largely in the nose or mouth or upper throat, while a certain number pass down into the air-tubes and lungs. A large part of this foreign material may be dis- charged from the nose where it is caught in the ^ \ & K A /? y it? UNIVERSITY 38 DUST AND ITS DANGERS. mucous which that organ secretes when irri- tated. A very considerable proportion of the in- breathed foreign material gets into the mouth and may be spat out or swallowed. The floating material which is carried past the well-guarded portals of the lungs and enters the windpipe and bronchial tubes and lodges on their moist walls finds here a most efBcient arrangement for its expulsion. Here is placed, completely lining the tubes, an army of thoroughfare-cleansers composed of individ- uals who are not in politics, who have no vote, and who present to us the unwonted, and at first puzzling, spectacle of street-cleaners whose business seems to be to clean the streets. Completely lining the larger air-tubes like a mosiac, are myriads of tiny cells shaped something like a narrow short club and set upon end side by side. Projecting from the free ends of each one of these cells is a number of very minute hairs, so that the whole cell looks something like a short club with a beard growing from one end (see Fig. 3). The whole inner surface of these air-tubes, then, is DUST AND ITS DANGERS. 39 lin^d with these delicate hairs which are called cilia. Now, these myriads of cilia, year in and year out, day and night, while life lasts, are con- stantly swinging their free ends back and forth, bending as they recover, and then with a quick L FIG. 3. — CILIATED CELLS FROM THE LARGE AIR-TUBES OF THE HUMAN LUNGS, SEEN FROM THE SIDE. HIGHLY MAGNIFIED. snap forward so that any small object which lodges on the walls of the larger air-tubes— since all the cilia act in rhythm — is swept up- wards toward the mouth, away from the peril- ously delicate and sensitive lungs. The movement of these cilia is less vigorous when the body is quiet, as in sleep, increasing m rap« 57 heredity of . . . . . • •'••• 59 importance of, as compared with other diseases . . 62 insidiousncss and slow beginning of . _ » . . 57 mode of transmission most common . . •» . 64 mortality from, in various cities . . . ... . 63 most direct means of preventing spread of . . .71 not always a hopeless disease .... 73, 101 INDEX. ID/ PAGE Consumption not one of the highly contagious diseases . . .94 of the lungs the most common form of tuberculosis . . 65 predisposition of certain persons to . . •' • 59 prevalence and mortality of . . . . . 57, 61 proper food and surroundings more important than drugs in the treatment of . . . ... 101 spread by meat and milk . . . . .64 summary of the reasons of prevalence of . j .. . 70 transmission of, in unclean sleeping-cars, bedrooms, and steamships ._••.. . . .'-»•.. 86 transmission of, to attendants upon the sick . ... . 68 tubercle bacilli the only direct cause of . . .* . 59 ways in which it is spread by dust . . . .58 Contagion .......... 93 Contagiousness, degrees of, in bacterial diseases . . . .94 Cornet, discovery of tubercle bacilli in consumptives' rooms . . .66 Cotton filters for bacterial air analysis . . . . .' . 14 Court-rooms, filthy and dangerous air of . . . »• . 83 Crime, toleration of filthy cities by the people a . . » . 91 Culture medium for germs . . . . % .• . 14 u methods for germs . . . . ... .11 Destruction of discharged material best means for preventing spread of bacterial diseases . . . .-• .99 Diphtheria ....... • • 55 Disease, preventable . . . . ~\ .• . .54 44 relation of dust to . . . . . . .50 Diseases, infectious . . . . . f . -55 44 " presence of bacteria in explaining many mysteries of . 91 " relation of bacteria to . . . . • 55 44 of occupation . . . . ... .5 Disinfection, modern notions of, more precise . . . . . 93 Drugs in infectious diseases . . . . . .96 Dundee, air analysis in . . . . . . .23 Dust, as means of spreading consumption or tuberculosis . . .58 44 " source of danger in public assembly rooms . . . .81 44 coal- and cotton- ........ 4 44 dangers of, in public buildings ...... 80 44 -dangers out-doors and in-doors ...... 74 41 definition of . . . . . . . . .a 44 filtration of, out of lymph in the lungs ..... 45 44 in-doors, germs in ,~~ — ....... 37 108 INDEX. PAGE Dust, harmful effects of, on the eyes ...... 52 " in inhaled air, disposal of, by body . . . . -37 41 4k public conveyances . . . . . . .84 44 " theatres, or as means of conveyance of disease . . .81 44 " railway carriages as source of danger . . . . .85 44 in-doors, danger of infection from ...... 76 44 inorganic elements of ....... 4 " " as causes of disease . . . .51 44 lodgment of, in tissues of lungs ...... 44 44 materials composing ........ 3 44 metallic ......... 4 11 mode of occurrence of bacteria in . . . . . .8 44 nature of, in general ........ i 44 organic or living elements of ...... *f 44 out-of-doors, micro-organisms in . . . . . .20 44 relations of, to catarrh . . . . . . .52 44 removal of, from houses ....... 77 44 safeguards of body against ....... 36 44 settling of, in-doors ........ 22 44 significance of, in causing disease ...... 50 1 sweeping away of, by ciliated cells ..... 39 41 street-, dangers of infection from ..... 75 44 tenacious clinging of, to fabrics ...... 29 tobacco- . ........ 5 41 tubercle bacilli in. . . . . . • .66 44 two modes of freeing air from ...... 100 14 woollen .........5 justing .......... 78 Elevated R. R. in New York as source of annoyance and danger from dust 52 Erysipelas .......... 55 Evolution, failure of, to eliminate the porcine element in street loafers . 98 Expectoration as a common vice . . . . . .97 44 dangers of, in consumptives . . . . .61 Eyes, harmful effects of dust on . . . . . . .52 Filters, air-, in biological air analysis ...... 13-15 " dust-, lymph-glands in lungs as . . . . . .46 Filthy cities, no necessity for ....... 90 Filtration method of air analysis ....... 15 General knowledge, necessary to prevent spread of bacterial diseases by dust 89 Germs, aerial modes of study of . . . . . . . 11-13 INDEX. 109 PACK Germs in in-doors dust ........ 27 41 in out-doors dust . . ... . . . .20 44 colonies of. . . . . . . . .12 41 nature of.. .......7 44 origin of, in in-doors air . . . . . . .30 44 safeguards of body against aerial ..... 36 Hotel bedrooms as sources of dust-infection . . . r. • . 89 House furnishing as affecting the risk of dust-infection . . .78 Immunity of body to disease germs ...... 49 In-doors air, analysis of ........ 27-35 Infection, dangers of, from street dust ...... 75 44 degrees of readiness of, in different diseases . . .94 Infectious diseases ......... 55 44 remedial agents in . . . . . • .96 Isolation of the sick as means of prevention of bacterial diseases . . 54 Lungs, most common seat of tuberculosis . ... . 65 44 pigmentation of, by inhaled dust . . . . .44 Lymph, filtration of, in the lungs ...... 45 Lymph-glands as dust-filters ....... 46 localized tuberculosis in . . . . . .67 Measles . . . . . . . . » . 55, 94 Meat, tubercular, as food, dangers of . . . . i . 64 Michigan, frequency of consumption as compared with small-pox in . 62 Micro-organisms in in-doors dust ....... 27 44 '4 out-doors dust . . * . . ' . .20 nature of ........ 7 44 safeguards of body against . . '. . .36 Milk from diseased cows, dangers of ...... 64 Motes in the sunbeam ........3 Moulds .......... 7 Mould-spores in air analysis ....... 18 44 *4 dust ........ 9 44 preponderance of, in wet weather . . . . 22 Neumann, air analysis by . .......33 New York, air analysis in . . . . . . . . 23-26 44 l4 filthy streets of ....... 21 Official negligence no excuse for private indifference to cleanliness . .90 1 10 INDEX. PAGE Petri's air analysis . . . . . . ....23 Phagocysts . . . .••'•' . . . 40-42, 48 Phlegm, removal of, by ciliated cells ...... 40 Plate method of air analysis ....... 15-18 Pneumonia ..........55 Predisposition to consumption . . % • , . « . .59 Preventable diseases . . . . . . . .54 Prevention of disease, a public and private duty . . . .88 li li " more reasonable than neglect and attempts to cure . 96 Public conveyances as sources of danger from infectious dust . « .84 Railway carriages as sources of danger from dust . « r • . 85 Rain, effects of, on number of aerial germs . . . . . 22 Reinfection of tubercular persons by expectoration . . . . 102 Rooms as repositories of dust and germs . . . . . .-"-99 Safeguards of body against dust and germs . . . . . 36, 75 Sand filters for biological analysis ...... 15 Sanitariums for consumptives ....... 102 Scarlatina . . . . . . . . . . 55, 94 Scavenger cells . . . . . . . . .41 School-rooms, dust in • . . . . . .84 Sleeping-cars as sources of infection . . . . . . 86 Small-pox . . . . . . . . . 55, 62, 94 Snow, effects of, on aerial germs ....... 22 Spitting-cups for consumptives . . . . , . 71 Spitting, dangerous and filthy nature of . . . . . . 72, 97 Sputum, dangerous nature of, in consumption . . . . . 60, 66 " proper means of disposing of, in comsumption . . .71 Steamships, state-roonis of, as sources of danger . , . . 86 Stein, experiments of, on floating dust . . . • '* .28 Sugar-felters in air analysis . , » . . • , 15 Sweeping, effects of, on aerial germs in rooms . . , , . 31-33 Theatres, dusty, dangers of , . . . . . . .81 u responsibility of the public for filthiness of . . . .83 " vicious methods of cleaning of ..... 82 Tubercle bacilli 48 " " growth of, in the body only under favorable conditions . 95 " habitat of • . « . . . v« . 64 41 " how spread in the air . . . . .64 ** " in dusty rooms occupied by consumptives . » - . 66 INDEX. 1 1 1 PAGE Tubercle bacilli in expectoration in tuberculosis of lungs . . .60 " " " the bodies of apparently he ilthy persons . . . 67 " " mode of action in causing consumption . . .60 " " not easily killed by drying ..... 65 u " spread of, by diseased meat and bad milk . . .64 44 " the sole direct cause of consumption . . -59 ki " vulnerability of, when growing with other germs . . 64 Tuberculosis . . . . . . . . . • 55^ 56 44 bacilli of, mode of action in causing . . . .60 44 frequency and mortality of ..... 61, 62 heredity of . . . . . . • -59 44 in other parts of the body than the lungs . ,. . 60 44 localized . . . . . . • .67 mode of transmission of . . ... ... 64 44 predisposition to- . . . • • . -59 41 spread of, by meat and milk ..... 64 4 "' " " dust 58 Tucker, air analysis by . . . . . . • . 23, 31 Typhoid fever . . . . . . . • • 55 Ventilation, effects of, on floating dust . . . • • 28 Vigilance necessary to prevent spread of bacterial diseases . » .88 Webster's definition of dust . . . . . »,.2 Wind, effects of, on floating dust and germs ..... 22 Yeasts .... ..... 7 Yellow fever ........ -55 THE END. Y.B 65690