L I B R.A R.Y OF THE U N I VER.S ITY Of I LLI N O I S VE. v. OAK' cnr T-mQp Digitized by the Internet Archive in 2019 with funding from University of Illinois Urbana-Champaign https://archive.org/details/veterinarianmont53unse VETERINARIAN A. 4 A MONTHLY JOURNAL OF VETERINARY SCIENCE ? D FOR 18-7R: VOL. LIIT-VOL. XX^, fourth series. EDITED BY PROFESSOR SIMONDS, ASSISTED BY PROEESSORS BROWN AND TUSON, AND T. SPENCER COBBOLD, M.D., E.R.S., E.L.S. Ars Veterinaria post medicinam secunda est. — Vegetius, LONDON: MINTED BY J. E. AD LAUD, BARTHOLOMEW CLOSE. PUBLISHED BY LONGMANS, GREEN, & CO. PATERNOSTER ROW. THE VETERINARIAN, VOL. LIII. No. 625. JANUARY, 1880. Fourth Series, No. 301. Communications and Cases. ON THE PROGRESS AND PRESENT STATE OF VETERINARY SCIENCE IN AMERICA. By John Henry Steel, M.R.C.V.S., F.Z.S., Corresponding Member of the Italian Veterinary Academy. V'ade Mecani of Equine Anatomy. By A. Liautard, M.D., V.S., Professor of Comparative Anatomy to the American Veterinary College, &c., &c. New York, 1879.— We gladly avail ourselves of the opportunity afforded to us by this work being placed in our hands for review to draw the attention of English veterinarians to the present condition of veterinary science on the other side oi the Atlantic. Such observations as we pen will perhaps not be con¬ sidered out of place if we remember that the woik whose title is placed at the head of this article is of much gi eater importance as a sign of the times than its elemental y cha¬ racter and small hulk would give it at other times and in othei places. Its author is Dr. Liautard, who is the leader of the veterinary profession in the United States, editor-in-chiei o the only American veterinary periodical, corresponding mem- her of the Central Veterinary Society of Pans, and wvinninal nf t>ip Vpt.prinavv School, which an impartial ex- Liu « 2 VETERINARY SCIENCE IN AME RCA. shows us to be doing the best educational work of any in the United States of America. It is dedicated to Mr. George Fleming, and is the first work of importance on 'Anatomy of the Horse produced in America, being preceded only by the obsolete work of Dadd. The Vade Mecum is very elemen¬ tary, though prepared for “ the use of advanced students and veterinary surgeons.’5 It is arranged in chapters, each on a region of which the various component structures are re¬ viewed seriatim ; it is not quite so free from errors as we should expect so elementary a work to be, while the imperfec¬ tions necessary to a condensed account of anatomical struc¬ ture are sometimes glaring. We must attribute these defects mainly to the demand for the work necessitating hasty pre¬ paration, and hope a second edition may soon afford scope for correction. We fully feel that the author’s pupils owe him a debt of gratitude for this work, the preparation of w'hich must have trespassed much on his valuable time. In January (1877) number of the American Veterinary Review the author gave a list of American veterinary works, as follows : Carver’s work, 1818 ; Budd’s work, 1861 ; Dadd’s works, 1866 (‘ Anatomy,’ ‘ Veterinary Journal,’ and ‘ Modern Horse Doctor’) ; works by Jennings and McClure ; W. C. Holme, ‘ American Farrier,’ 1852; Herbert, ‘Hints to Breeders, 1859; translation of Guenon, ‘ Milch Cows/ by Trisk, 1868 ; ‘ American Farmer’s Horse/ by R. Stewart, M.D., V.S., 1866; ‘ Percheron Horse / by C. Du Hays, 1868 ; ‘ American Cattle/ by L. F. Allen, 1868 ; ‘Appendix to Stonehenge/ by A. Large, M.D., M.R.C.V.S., 1869; J. Harris on the £ Pig,’ 1870; J. A. Reason on the ‘ Hog/ 1870; Hanover on the ‘Law of Horses/ 1872 (2nd ed., 1875) ; Bouley’s ‘Hydro¬ phobia/ translated by A. Liautard, 1874 ; J. Law, ‘ Farmer’s Veterinary Adviser/ 1876. Since that time Dr. Tellor brought out a popular work on ‘Diseases of Live Stock.’ This list, even allowing for omissions, seems meagre enough until we come to consider the influences acting °on the progress of the American veterinary literature. Profes¬ sional writers need a reading professional public, such as America until recently has not afforded, though now we hope she is in a fair way to encourage much energy in this direction. Again, when veterinary science was introduced into English' speaking America, she had at her disposal such works as the professional labours of British writers had pro¬ duced. We see the impress of this still in the list of text¬ books recommended at the schools, the works of Williams Fleming, and Dun having a well merited prominence! VETERINARY SCIENCE IN AMERICA. 3 £10.0-5 ME v. o* 3 CP— vi n The American Veterinary College names the work we have under notice, and Fleming's translation of Chauveau as anatomical text-books. We might suggest the addition of Professor Vaughan’s edition of f Strangeway’s Veterinary Anatomy.’ Of course we must not forget that the American laws, as becomes those of a free nation, prove exacting to importers of foreign works, causing an increase of 75 per cent, on the native price in some cases, and therefore remov¬ ing aids from the reach of the poor student. This, how¬ ever, is counterbalanced by the enterprise of the American publishers, who advertise one English work at a price con¬ siderably less than it costs in this country ! (See Veterinary Journal , July, 1869.) The influence of English literature is perceptible in an advertisement published monthly by a leading New York firm, which has some noteworthy points. We believe none of the works therein mentioned are American. Mr. Fleming3 s name is not mentioned in connection with his f Sanitary Science and Police;’ Professor Williams is a F.R.S.C., and we are surprised to find ourselves a M.R.C.V.C., whatever that means ? Perhaps an additional-e appended to our name alters our professional qualification! These points we men¬ tion as well in the interests of our American confreres as ourselves. One of the most highly educated of them (Mr. Billings) complains bitterly of this defect in American legis¬ lation, which he justly terms a “ Tax upon Brains.” We now turn with pleasure to the American Veterinary Review, of which the first number appeared in 1877 (January), as the organ of the United States Veterinary Medical Associa¬ tion, under the editorship of Dr. Liautard, assisted by A. Lockhart, M.R.C.V.S.; later we find Mr. Lockhart replaced by three members of the staff of the American Veterinary College — A. Large, M.D., M.R.C.V.S. ; J. L. Robertson, M.D., V.S., and A. A. Holcombe, D.V.S. Now Dr. Liautard is assisted by “ a selected staff of veterinary practitioners.” We have examined all the volumes of this work with care, for we wished to draw from its pages the lines of thought of co our Transatlantic cousins, to trace any inherited British characters, and to solve the difficulties which prevent us co from thorough appreciation of the value of American veteri- ^ nary degrees. Removed as we are by space from the country of which we write, and having only personal sym¬ pathies with those who, like ourselves, are zealous to promote professional progress, we are perhaps in a position to point out what we can learn from America, and what we may teach in return. We are much indebted to Professor Liautard s •s .3 4 VETERINARY SCIENCE IN AMERICA. papers on the history and progress of veterinary medicine in the United States, in the first number of his journal, and to his subsequent editorials, and especially also to the papers on veterinary education by Professor McEachran, of Montreal. The American Veterinanj Hevieio takes a broad view of veterinary science, its needs, its progress, and its various subdivisions. It notes progress in European countries, and by every means in its power endeavours to promote profes¬ sional unity and a higher standard of education of veterinary surgeons. Its editor several times appears before us as an advocate for enlargement of the journal and reduction of its price ; he acts for the United States Association, and seems to enjoy the entire confidence of the members of that influential body. In his paper above mentioned, he tells us that the first qualified practitioner in New York State was Rose, a Prussian graduate, 1817. Shortly afterwards Grice, a London gradu¬ ate, and some members of the Royal College of Veterinary Surgeons appeared — Messrs. Curtis, Lockhart, Pilgrim, and Budd, the latter author of a treatise on the ‘Foot of the Llorse/ 1831. In 1857 Dr. John Busteed succeeded in obtaining from the State Legislature a Charter of Incorporation of the New York College of Veterinary Surgeons. He associated with himself Mr. Ralston, M.R.C.V.S., formerly of the Indian army, and they constituted the faculty, which proved in¬ sufficient for its duties, and the school was closed. It had started in a handsome building erected by private subscrip¬ tions, which was burnt down in 1865 or 1866. Dr. Busteed's ardour prevailed against this discouragement. He again, in 1864, organised the school, assisted by Drs. Liautard and Large and Mr. Copeman, Dr. Liautard holding the chair of Comparative Anatomy and Surgery. In 1870, Dr. Busteed retired and six gentlemen formed the faculty, of whom Drs. Liautard, Large, Stein, Percy, and Robertson still hold office. Dr. Weisse having been replaced by A. A. Holcombe, D.V.S., in the chair of Surgical Pathology, and Dr. Lyons having relieved Dr. Percy of Chemistry, leaving him lec¬ tures on Materia Medica and Therapeutics. Dr. Liautard retains his original subjects, and with them takes Sanitary and Clinical Medicine; Dr. Large, who is a M.R.C.V.S., takes the Theory and Practice of Veterinary Medicine and of Clinical Medicine ; Dr. Robertson, Cattle Pathology, Obste¬ trics, and Clinical Medicine ; Dr. Stein, Histology and Com¬ parative Physiology ; Mr. Coates, D.V.S., is Demonstrator of Anatomy ; and Messrs. J. Rogers and R. A. McLean, both D.V.S., lecture on Pharmacology and Anatomy respectively. These officers, however, do not now belong to the NewYork Col- VETERINARY SCIENCE IN AMERICA. 5 lege, for difficulties which occurred about 1873 led to secession of the whole teaching staff, who, under Professor Liautard, founded the American Veterinary College. The original in¬ stitution closed its doors, again flickered into life, and an expiring spark of it recently appeared when a memorial was signed by some of its graduates endeavouring to obstruct the sanitary efforts adopted for repression and eradication of pleuro-pneumonia zymotica. After this let us hope it will no more be seen nor heard. A curious feature of its exist¬ ence was presented in 1868, when the faculty lectured to a class of one student. We have before us the Annual Catalogue and Announce¬ ment of the Columbia Veterinary College and School of Comparative Medicine, New York, on the back of which is a 'woodcut of the said college,, which we are assured on credible authority is not accurate in all particulars. It has one room with six windows, indicated as the “ Canines Hospital,” and an equally large pathological laboratory. We find on opening this catalogue a request if we are not interested in veterinary science to hand it on to some one who is. We find among the councillors the name of Chas. P. Lyman, veterinary surgeon; this is C. P. Lyman V.S.E., who in 1877 was appointed veterinary lecturer to the Massa¬ chusetts Agricultural College. He writes to the Revieio to say he has not sanctioned the insertion of his name, and does not like the company. The staff includes seventeen officers. Specialism is carried to its highest extent, there being a professor of veterinary ophthalmology, a lecturer on animal hygiene, a teacher of jurisprudence of veterinary medicine, a lecturer on ornithology and diseases of domestic fowls. The demonstrator of anatomy graduated in 1879. The list of prizes occupies a prominent position in the cata¬ logue. Mr. J. A. Going, ork, apparently very little worse, but how different is the result if the nail, be it only a small one, and small ones, I find, generally do the most harm, happens to have per¬ forated anywhere about the point of the frog, probably injuring the tendon of the flexor pedis and resulting in open joint, and, perhaps, tetanus. In these cases the pain is often so acute that sympathetic fever and even death is the result. Of course, our first care must be to alleviate the constitutional symptoms. I generally give in the first place a dose of purgative medicine, and then administer three or four times a day the fever mixture, as mentioned in the early part of this paper. I have the sole thinned till it gives to pressure, and apply warm fomen¬ tations and soothing applications to the wound, as solution of Liq. Plumbi, or covering the wound with powdered camphor or Ext. Belladonnse, and put the foot into a good warm bran poultice. It too often happens in these cases that the nail has perforated either into the joint or so near that, from the amount of inflammation set up, the joint becomes opened. When the injury is of such a character as this the case generally terminates fatally. I have had very many such cases, and with varying success in treatment. I have tried almost everything in its turn. Should the coffin-joint be open and a large discharge of synovia, I have sometimes used a single injection of solution of Hy. Chlor. ^j to 5j, or tincture of iron, just within the wound. At other times, and, I think, with the most success, have injected Liq. Plumbi pure, then applied externally on a large pledget of tow a powder consisting of Pulv. Alum., Pulv. Aloes, and flour, and leave it for a day or two, keeping the foot as perfectly at rest as is possible, and have cold wet flannel bandages applied to the coronet. In other cases I have applied a good smart blister to the coronet, but it too often happens when the injury is of the serious nature I have described that do what we will the animal suc¬ cumbs. Should, however, the discharge of synovia be arrested, the animal not suffering so much pain, and making a little use of the foot, then we have good ground for hope. I should now commence to dress the wound with Ung. Zinci Sulph., applied on good pledgets of tow, and stimulate the coronet with repeated mild blisters, and after a short time has elapsed turn the animal out to grass, the walking about and using the foot often being of great service. And now, gentlemen, in conclusion I must thank you for the patient hearing you have given me. Very imperfectly I have endeavoured to place before you a brief outline of some few of the various injuries to the feet which are daily brought under our notice. I am not presump¬ tuous enough to suppose that I have told you anything but what you were already acquainted with, but I do hope that the observations I have made, crude though I know they are, may be the means of eliciting the opinions of all here, and that the discussion which will ensue may tend to a further knowledge of the subject, remembering the words of the wise man, “In the multitude of counsellors there is wisdom.” A discussion followed the reading of this paper, in which all the members present took part, and the further discussion on it was post- posed until next meeting. G. It. Dudgeon, lion. Sec. 73 THE SCOTTISH METROPOLITAN VETERINARY MEDICAL ASSOCIATION. The quarterly meeting of this Association was held on Wednesday the 10th December, in the London Hotel, Edinburgh. Mr. Rutherford, Edinburgh, presided, and the following gentlemen were present : — Professors Walley and Baird, Edinburgh Veterinary College; Professor McCall, Glasgow Veterinary College; Messrs. Aitken, sen., Edinburgh; Borth- wick, Kirkliston ; Young, East Calder ; Balfour, Kircaldy ; Kirk, Edin¬ burgh ; Connochie, Ayton ; Brown, West Calder ; A. Baird, Edinburgh ; Reekie, Edinburgh ; Reid, Leith ; and the Secretary. The office-bearers for the ensuing year were elected as follows : — Mr. Connochie, Selkirk, president ; Messrs. Aitken, Borthwick, and Young, vice-presidents ; the present secretary was re-elected. The President gave notice that at next meeting he would move for the appointment of a visiting committee to wait personally on members of the Association and other veterinary surgeons, within reasonable distance of Edinburgh, with a view of inducing them to do all in their power, by regular attendance and otherwise, to contribute to the well-being of the Society. The Secretary read a communication which he had received from the secretary of the Liverpool Veterinary Medical Association, requesting the members to consider a resolution passed at a recent meeting of that society. The resolution was to the effect — “ That the members of the Liverpool Veterinary Medical Association were not prepared to submit to the profession the name of any gentleman as a substitute for any of those gentlemen who retire by rotation in May, 1880, from the Council of the Royal College of Veterinary Surgeons.” Some discussion on this subject ensued, and the members were unani¬ mously of the opinion that, while some of the gentlemen referred to in the above resolution deserved their support, the Association should take steps to secure the better representation of the Scottish section of the profession. The Secretary was desired to thank the secretary of the Liverpool Veteri¬ nary Association for his communication, and to reply to this effect. Mr. Rutherford, Mr. Borthwick, and the Secretary were appointed a Committee to issue circulars to the holders of the veterinary certificate of the Highland and Agricultural Society, pointing out the advisability of at once obtaining the diploma of the Royal College of Veterinary Surgeons, as a means of qualifying themselves to vote at the next election of members of Council. Mr. Rutherford exhibited a patent composite horseshoe. The shoe was of a material which somewhat resembled in appearance and pro¬ perties gutta peroha. It had been made and patented at considerable expense, and was stated to be very durable, besides having other advan¬ tages. It was fixed to the hoof, not in the ordinary manner, but by means of screw nails. He had caused the shoes to be worn on horses doing only halt work, and found that they did not last more than three days. Professor Walley showed the oesophagus of a three-year-old cart colt, which was immensely dilated. The case occurred in the practice of Messrs. Corbett and Pringle, Newcastle, the animal having been pur¬ chased by the owners the day prior to death, and turned into a grass park for the night. When seen by Messrs. Corbett and Pringle he was in a desperate°condition, breathing with great difficulty, coughing violently, 74 SCOTTISH METROPOLITAN VETERINARY MEDICAL SOCIETY. and discharging large quantities of saliva from the mouth. These gentle¬ men diagnosed dilatation and impaction of the oesophagus, and prognos¬ ticated a speedy fatal termination of the case. The prognosis was shortly verified. The oesophagus, trachea, larynx, and a small portion of lung, were sent to Professor Walley for inspection. The gullet was im¬ mensely dilated throughout. At the most dilated part its circumference was fourteen inches-. The muscular layer was hypertrophied to the extent of half an inch, but otherwise it was healthy. No stricture or organie disease existed either in the gullet or cardiac orifice of the stomach. The left laryngeal muscles were atrophied ; the laryngeal and tracheal mucous membranes inflamed. Both larynx and trachea were filled with a frothy fluid, mixed with ingesta. The small portion of attached lung showed considerable carnification. The difficult question to solve in the case was the cause of the dilatation, as no mechanical obstruction to the passage of ingesta existed. Death had evidently been caused by asphyxia, as the result of the passage of ingesta into the bronchial tubes, probably in the act of vomition. Professor Walley also exhibited the bones of the hock and fetlock of a cow, showing the results of diffuse metatarsal periostitis. Subject. — A small Ayrshire cow ; aged. History. — His attention had been directed to the animal during his course of inspection of dairies, about six weeks prior to death, when she was in slings, and under the care of Mr. Butherford. He had then ob¬ served that the leg was enormously swollen, and that two or three fistu¬ lous openings existed in the fetlock and hock -joints respectively. A discharge similar to that usually found in sinuses issued from the open¬ ings, and there was evidence, in the shape of cicatrices, of others having existed. The animal was in low condition, but was eating, and giving a tolerable quantity of milk. There was no sign of organic disease of internal organs, nevertheless he had a strong suspicion that the disease might have had a tuberculous origin. After the death of the animal Mr. Rutherford afforded him the oppor¬ tunity of examining the leg. The skin and subcutaneous tissues were thickened to the extent of from one to two or three inches. The external fistulous opening of the hock corresponded to cloacae in the joints, from the orifices of which, masses of degenerated ligamentous structure protruded. The whole of the soft structure of the fetlock-joint had undergone molecular degeneration, and large portions had been cast off through the fistulous opening, the extremities of the bones entering into its composition being eroded from absorption, entirely deprived of periosteum, and absolutely dead. The ligaments of the corono-suffraginal and corono-pedal articu¬ lations, with the tendons clothing them, were undergoing gelatinous degeneration. After removal of the soft structures by boiling, extensive destruction by caries of the articular surfaces of all the tarsal bones was seen to have taken place, large quantities of new ossific matter having been thrown out round the joint and all round the upper three fourths of the metatarsal bone, the latter being completely encased. No trace of tubercle existed in any of the diseased tissues, and he was of opinion that the affection was local in its origin. A short discussion afterwards ensued on the subject of the paper read by Professor Walley at the previous meeting. John McFadyean, Secretary. 75 MONTREAL VETERINARY MEDICAL ASSO¬ CIATION. This association held its first meeting for the session 1879 80 on Thursday evening last, October 9th, in the lecture room of the college. Principal D. McEachran was in the chair, with a full attendance of members. In his opening address the President briefly reviewed the past history of the association since its formation in 1875. It was very gratifying to notice the continued and increasing interest evinced by the members in the meetings. He directed the attention of the younger members to the great benefit they would derive from their connection with the association. The papers read being always most interesting, and frequently on subjects not fully treated upon in the regular curriculum, were of great advantage to them all. The library, containing as it did nearly 300 volumes, and many of them rare and valuable works, was always at their disposal. It afforded him great pleasure to be able to inform them that its numbers were con¬ stantly being increased by donations from friends of the association. Several volumes had recently been received from Dr. Fenwick, Dr. Lieutard and Dr. C. C. Lyford. In conclusion, he would state that the success of the association had exceeded his most sanguine expectations, and he would urge upon the members the necessity of continued exertion to maintain its reputation. The officers of the association are — Dr. McEachran, F.R.C.Y.S., Honorary President; William Osier, M.D., L.R.C.P.L., President; C. J. Alloway, V.S., first Vice-President; James Bell, M.D., second Vice-President; M. S. Brown, Secretary and Treasurer; and William Jakeman, Librarian. A vote of thanks was proposed and carried unanimously to Drs. Fenwick, Lieutard, and Lyford, for their kind donations to the library. The following gentlemen were proposed for membership : — F. Tor¬ rance, Compton, P.Q. ; A. J. Chandler, Coaticook, P.Q. ; Messrs. Thomas and Skully, Boston, Mass. ; Mr. Dunden, Salem, N.Y. ; A. Glass, Philadelphia, Penn. ; W. Wardle, Montreal, Quebec. At the next meeting (Oct. 23rd) Principal McEachran read a paper on “ Contagious Pleuro-pneumonia,” a subject that, at the present time, is one of especial interest, not only to the members of the profession, but to all that are connected with the breeding and exportation of cattle, and Mr. M. S. Brown communicated a case. The fortnightly meeting of the Montreal Veterinary Medical Associa- was held in the lecture room of the college on Thursday evening, Novem¬ ber the 20th, Professor McEachran in the chair. After business of association was finished the chairman called upon Mr. Peter Cummings to read his communication on “ Superficial Necrosis of the Os Pedis.” Mr. Cummings described the case in full detail. The reading of the same was listened to with great interest by those present. Mr. Charles Ormond , of Milwaukee, read a very interesting paper on 76 MISCELLANEA. “ Bone Spavin,” in which he evinced a more than common knowledge of the nature of this disease, the causes on which it depends, and the changes that take place in the joint. In his treatment he described a method much practised by his father, Mr. W. M. Ormond, of Milwaukee, by which he claimed to be more than ordinarily successful in restoring the animal to usefulness, viz. cauterisation of the joint by a pointed hot iron, inserted between the bones, by which anchylosis was produced. A most animated discussion followed, in which the whole question was fully and intelligently discussed, the majority favouring, as more rational, the plan taught by the President, of firing and blistering completely around the joint. The notorious prevalence of spavin in horses in Canada, especially in the poorer parishes, where proper attention is not paid to the selection of breeding stock, was fully commented upon. Where spavined horses or mares are used for breeding, this disease is very common, and the losses entailed by rearing worthless animals were incalculable. Too much cannot be said to urge farmers to stop breeding from unsound animals. The meeting was one of unusual interest. The next papers were read on December 3rd on “ Tuberculosis in Cattle,” by Mr. William McEachran, and one on “ Veterinary Dentistry,” by Mr. J. B. Green, Ohio. ARMY APPOINTMENTS. The Gazette , Dec. 16th, announces that Veterinary Surgeon William James Masters, Royal Artillery, is placed on temporary half-pay. The Cape Town Gazette , of Aug. 18th, states that Mr. Thomas Butcher Scott Dawkins, M.R.C.V.S., has been appointed Veterinary Surgeon to the Cape Town Riflemen. We also learn that Mr. Edmund Woods Goldsmith, M.R.C.V.S., has received an appointment to a Native Indian Cavalry Regiment. OBITUARY. We have to record the death of Mr. Wm. Heaps, M.R.C.V.S., who died Dec. 6th, at Fulwood, Preston, aged 42. His Diploma bears date April 28th, 1859. Also of Mr. J. Mason, M.R.C.V.S., London. Diploma dated May 14th, 1851. And of Mr. Harry Low, M.R.C.V.S., who died on December 17th, at the residence of his brother at Norwich, in the twenty-fifth year of his age. His diploma bears date July 18th, 1878. MISCELLANEA. From Punch’s Happy -thought Guide to London. Veterinary College. — Qualification — to be able to pronounce and write the name correctly — after dinner. Open Vet or fine. THE VETERINARIAN. VOL. LIII. No. 626. FEBRUARY, 1880. Fourth Series, No. 302. Communications and Cases. SYNOPSIS OF CONTINENTAL VETERINARY JOURNALS. By John Henry Steel, M.R.C.V.S., F.Z.S., Demonstrator of Anatomy at the Royal Veterinary College. Summary. — Recent Researches on “ Charbon,” by MM. Pasteur, Colin, Arloing, Feser, Cornevin, Chamberland, and Roux, from the Recucil de Medecine Veterinaire, and the Journal de Medecine Veterinaire et de Zootechnie. The activity of experimental observers abroad is mani¬ festing itself in numerous researches on the various ques¬ tions which the diseases comprised under the term charbon present. These are of the highest interest to us at the present time in this country, for, thanks to Dr. Greenfield and his colleague at the Brown Institution, England has not been behindhand. We shall endeavour to briefly sum¬ marise the new facts which recent foreign investigations have added to our store of knowledge of this subject. M, Chauveau* s paper, “ On the influence of management or race on the liability of Sheep to become affected with Splenic Fever,” takes precedence in time, and in its general import¬ ance, as tending to materially alter our theories on the general nature of infectious maladies and their prevention. We are aware that while animals of some kinds are suscep- liii. 6 78 SYNOPSIS OF CONTINENTAL VETERINARY JOURNALS. tible of charbon on inoculation under almost any conditions of surrounding circumstances, others remain unaffected, unless the conditions are of a highly special character, as witness MM. Pasteur and Joubert’s experiments with fowls. Also some species with difficulty receive the disease, be the surrounding conditions favorable or otherwise. The author asserts that these differences exist also between animals of the same species but of different rearing and parentage. When occupied during last spring in experi¬ mentally elucidating the general theory of infectious dis¬ eases at his course of practical medicine, he inoculated among others certain Algerian sheep, and all these resisted the disease. He had previously observed immunity in cer¬ tain sheep, but attributed it either to defective material or unsatisfactory inoculation, but among other facts he ob¬ serves two cases. In the first, a sheep was inoculated with matter from a cow, but exhibited no signs of disorder, though death resulted in two rabbits similarly treated. In the second case, the inoculation matter was taken from a goat which died from spontaneous charbon ; this was intro¬ duced into a merino sheep which it killed in thirty-six hours. A portion of the spleen of that sheep, extremely rich in Bacteria, was pressed in a mortar with a little water, and supplied, after filtration, a liquid abounding in the agents of charbon infection. Of this eighteen drops were injected into the jugular of a merino ram. A quantity of the same material was injected subcutaneously on the left thigh of a sheep of the same breed, also six inoculation punctures with a lancet charged with blood from the spleen were made on the right thigh. The ram died of charbon on the ninth day at 5 a.m. As for the sheep, it resisted the inoculation, manifesting no ill results except an abscess at the seat of puncture of the left thigh, which opened on the sixth day and healed readily. The author concludes that the former may have been an imported African sheep, and that the latter illustrates the fact that animals may, on French soil, acquire an inaptitude for the reception of charbon. Around Lyons now are found many sheep imported from Algeria, either of the pure Barbary breed or more or less crossed with the large- tailed Syrian sheep. “ I have had bought, in different lots, nine of these animals of clearly ascertained rearing (with one exception) and of undoubted origin. All of them proved absolutely refractory to the culture of Ba¬ cillus anthracis. The attempts to convey charbon to these by inoculation were repeated in one case as many as five, generally three times, and in one case only twice. The SYNOPSIS OF CONTINENTAL VETERINARY JOURNALS. 79 matter used was most carefully selected from various sources and introduced by various methods, and it destroyed indi¬ genous sheep and rabbits on first trial. If immunity is the attribute of Algerian sheep as imported it is essential to examine whether it is a congenital character, or acquired either from the native soil or during the journey necessary to their arrival in France. If this is a congenital character it will be important to accurately establish what beneficial results may be derived from it, as well with regard to the special bearing of this one point as to its general scientific applications. If it has been acquired it is of great import¬ ance to learn how it has been acquired, for by determining its causes we may be able to experimentally realise them, and thus confer immunity on our docks.5’ The paper in the Journal de Medecine Vet er inair e for October and No¬ vember, 1879, gives the series of experiments, on which the learned professor bases his conclusions, in detail, and then continues : “ Except in the experiment of introduction of 8,000,000,000 of Bacilli into the jugular, the subjects showed no appreciable disturbance of their general health ; never¬ theless, those inoculated by punctures through the skin pre¬ sented as local phenomena a more or less marked tume¬ faction of those lymphatic glands nearest to the seat of inoculation ; besides, as a general phenomenon, especially after the first inoculation , there was a certain elevation of the internal temperature taken at the rectum. In the experiment where a cubic centimetre of the charbonaceous blood was introduced into the veins the subjects exhibited marked disorder, which commenced immediately on injec¬ tion, and lasted about twenty hours. This was of a febrile character, the temperature rising from 40 6° to 43°. During the height of the fever not a single bacterium could be seen in the blood ; probably the disorder was due to a true toxic agent existing in the blood with the Bacilli. The fever may, however, have been due to the Bacteria becoming temporarily entangled in some of the capillaries before undergoing dis¬ integration.” The author next discusses the question — Why Algerian sheep are so unfitted for culture of Bacillus an- thracis? MM. Pasteur and Joubert have shown that by reducing the high temperature of fowls they may be ren¬ dered susceptible of reception of the charbon, but a sheep was kept in cold water and did not become affected after inoculation. Again, the temperature of sheep dying of charbon falls below 40°, the normal of the Algerian breed. The cause of immunity must, therefore, be sought in some other condition than high temperature. 80 SYNOPSIS or CONTINENTAL VETERINARY JOURNALS. Professor Feser, of Munich, had been accustomed to test doubtful cases of charbon by inoculation of white rats, which multiply rapidly, and are therefore generally available. But he observed that sometimes his rats exhibited a marked immunity from the ill effects of inoculation. Further ob¬ servation assured him that this was the case with those fed on meat, hut not with those kept on a vegetable diet. He determined to prove this by special experimentation. His methods and results occur in the Wochenschrift f. Thierheil- kunde und Thierzucht , Nos. 24 and 25, 1879. He placed his rats in two sets, and for several weeks fed one lot on flesh alone, the other only on bread. With the same virus he afterwards inoculated animals from each set, and found that while those of the first set resisted the disease those of the last rapidly succumbed to it. (1) A rat fed on bread : injected subcutaneously inside the left thigh three drops of anthrax blood. Died after eight days, and the tissues abounded with Bacteria. The serous fluid of this animal killed a rabbit in three days. (2) Four rats . fed essentially on meat inoculated subcutaneously inside left thigh with blood and pulp of the kidney of a goat which died the night before. All remained healthy, though a rabbit similarly inoculated died of charbon five days after. (3) Two of these rats again similarly inoculated, though the fluid used sufficed to destroy a rabbit and a goose, suffered no harm. (4) A rat previously unsuccessfully inoculated was again subjected to the action of a drop of blood from the heart of a calf which died from anthrax the evening before. A negative result. After five weeks'’ exclusively bread diet the same animal was similarly inocu¬ lated, and died of charbon in thirty-two hours. (5) A female rat, previously unsuccessfully inoculated, having been fed on flesh only, brought forth nine young ones. The family was fed on thirty grammes of anthrax meat, and again the same, with bread steeped in anthrax blood. No harm ensued. But the mother’s diet was changed to bread* She was then fed on the flesh of a rabbit suffering from charbon for two days. She was found dead in her cage three days after. Of the nine young ones, three were placed with three of the progeny of another mother, and fed only on cooked beef and horse flesh, while the remaining six were fed on bread. All of them were inoculated with the same quantity of charbon blood from the heart of a rabbit ; all those fed on bread died rapidly between the twenty-second and thirty-second hours ; the six fed on flesh remained perfectly healthy. (6) Three rats were kept in the same SYNOPSIS OF CONTINENTAL VETERINARY JOURNALS. 81 cage ; one was kept in a different compartment from the other two, and fed only on bread for six months. Each was inoculated with anthrax blood ; only the one fed on bread died, the others remained in perfect health. From these experiments it may be concluded that the state of nutrition dependent on a certain diet exercises a considerable influence on the liability to become affected with anthrax. Feser concludes that the immunity of birds is not dependent upon their high internal temperature, as Pasteur supposes, but upon their alimentation. M. Pasteur, at the sitting of the Academy of Medicine of 17th September, 1879, presented the account of his re¬ searches on the etiology of anthrax. His previous researches, which we have already presented to our readers, reduced the matter to one question — whether it is possible to detect on the surface of the soil of the locality under examination the germs of Bacteria, particularly in those numerous spots where animals affected with charbon have scattered the germs either before death or after death, especially at the place of burial. The experiments undertaken to throw light on this question, with the aid of MM. Roux and Chamberland, consisted of two distinct series. In the first an inquiry was made as to whether, when charbon blood is added to earth, the Bacillus is preserved and undergoes multiplication in the mixture, especially when the earth is watered with urine and like fluids. These experiments all gave positive results. Under these influences the bacterium mul¬ tiplies in the earth ; it undergoes its developmental changes, so that its germs can be detected after months of alternate dryness and moisture. The second series of experiments is decisive in another matter. The carcase of a lamb which succumbed to charbon was buried. Ten months afterwards soil was collected from the surface of the ground where the animal was buried ; this was found to contain germs of Bacteria, which gave rise to charbon when introduced by inoculation into guinea-pigs. Soil collected from the deep layers gave rise to septicaemia of a special kind. M. Colin’s negative results of experiments of a similar character Pasteur attributes to the difficulties which impede detection of the germs in the soil, resulting from the multiplicity of germs of various microscopic species, which occur in all natural earths. Pasteur’s positive results overbalance Colin’s negative conclusions, urges M. Bouley in the Recueil de Medecine Veterinaire , 15th November, 18/9. Also they agree very markedly with clinical observations of these diseases. They show clearly that what is true within the 82 SYNOPSIS OF CONTINENTAL VETERINARY JOURNALS. laboratory is also true beyond its walls ; and we do not despair of seeing M. Colin adopt M. Pasteur’s views, as we did once before, when irrefutable experiments showed him that fowls may be rendered susceptible of charbon by placing them in determined conditions. Prom a practical point of view, the positive results of M. Pasteur and his colleagues on the etiology of charbon cannot and ought not to fail in leading to rigorous measures of sanitary police to prevent that which is now appropriately termed culture of the disease. Thus, the cutting up of carcases, except in knackers’ yards, should not be allowed ; for wherever it is performed it sows the soil with germs in the blood shed, and also the blood which remains in the skin or on its sur¬ face makes it a receptacle for germs. “ Again, burying must be supplanted by some more complete and rapid means of destruction, as, for example, cremation of the entire carcase by means of ordinary kilns, which could be constructed and supported by general subscription. In the neighbourhood where charbon is rife these should be so near to one another as not to leave a too great distance between them. Prefer¬ ably we might make use of the movable kilns suggested by M. Kuchborn, which we shall describe in some of our early chroniques .” Wanting these means, breaking up the carcase should be preferred to simple burial, but faute de mieux , the remains should be buried in some substance capable of destroying organic matters in a very short time, and the superficial layers of the earth covering the graves should for some time receive special attention in the form of lime dressings, or watering with some germ-destroying liquid. In a letter to the editor of the Reeueil for the 20th November, 1879, MM. Arloing and Cornevin discuss the question, “ Does a symptomatic charbon occur ?” Feser and Bollinger’s researches, they consider, have not completely resolved the question, for their inoculations, when they proved fatal, probably did so as a result of septicaemia, judging from the quantity and quality of the inoculated matter. M. Arloing undertook experiments to settle this question, associating with himself MM. Cornevin and Thomas. Splenic fever and symptomatic charbon (Chabert) show themselves side by side in that part of Haute Marne watered by the Meuse termed Bassigny ; the second disease occurs, especially at the commencement and end of the winter, in young cattle from six months to four years old. It appears suddenly ; the animal is dull and has no appetite, and often there is lameness, at first obscure, but later it is SYNOPSIS OF VETERINARY CONTINENTAL JOURNALS. 83 found to be attributable to the development of a swelling on one of the limbs. This usually occupies the upper part of the limb, but in some cases it appears on the trunk, as in the jugular channel, the intermaxillary space, or the lumbar region. Wherever it occurs the tumour is irregular in form and without defined limits, and spreads with striking rapidity. In eight or ten hours it has attained a great size. At first homogeneous and extremely painful all over, it gradually loses its sensibility from the centre, and becomes crepitant and sonorous, like a bladder filled with air. All its parts are black and pulpy. When incisions are made they give exit in the early stages to bright coloured blood, later to a liquid resembling venous blood, and later still to a frothy serosity. Meanwhile the fever increases, the pulse is hard (90 to 110 per minute), the respiration becomes painful and accelerated, the temperature of the skin very much elevated. The patient becomes feeble, listless, and staggers in his gait. The loss of power increases until the animal falls, where he remains stretched on the ground. The skin becomes cold, convulsions set in, and the case terminates in death, gene¬ rally from thirty-six to forty-eight hours after the first appearance of the symptoms. If the jugular be opened during the course of the attack it will be found that the blood is thick and black, and coagulates rapidly, and does not separate its serum from its clot sooner than healthy blood. Of course our readers will recognise this description of (c black quarter/’ The question under discussion, there¬ fore, is of great interest to us, for Dr. Greenfield, in his recent lectures, has reminded us that we are by no means thoroughly acquainted with the pathology of this affection and its rela¬ tions to splenic apoplexy. Attempts were made to repro- duce this disease by means of inoculation. The recent investigations on splenic fever had suggested the proper course to follow in the research — 1. To examine minutely, under the microscope, blood from the heart and large blood¬ vessels, also the pulps and liquids obtained from local lesions and lymphatic glands. 2 . To cultivate the diseased pro¬ ducts, either in the organism by inoculations varying in methods of different healthy animals, or in a moist chamber, or in Pasteur’s tubes, with aqueous humour or urine as a medium. i( Our experiments may be grouped in five series, according to the source of the inoculation material used - (1) From a charbon tumour before death, (2) or after death. (3) From a diseased lymphatic gland after death. (4) From the circulating blood. (5) From the blood-circulating system after death. Whatever the source of the matters 84 SYNOPSIS OF CONTINENTAL VETERINARY JOURNALS. which we have examined, either at the infected locality or at Lyons, we have never been able to determine the presence of Bacteria. We only have found a more or less marked presence of corpuscles, refractive at their centres, but with dark peripheries, the nature of which we could only decide by culture or by inoculations. Besides, as we could not say absolutely that no Bacteria were present, it was necessary to prove this by inoculation or cultivation. Cultures in a moist chamber with aqueous humour and in Pasteur’s tubes with acid or alkaline human urine gave no Bacilli anthracis. As for our inoculations, numbering now thirty-four in all, they have been made by different methods, and on animals of various races and species, in order to neutralise the chance of any deficiency in receptive power of the organism, or of the animal inoculated. Sometimes inoculation was performed by incision through the skin with a lancet, some¬ times by hypodermic injection, and sometimes by injection into the veins. The animals inoculated were three young oxen, three sheep (one a cross-bred merino of Bassigny, the others of an Auvergne breed), two horses, and twenty-six rabbits and mice. All these gave negative results, not one of the animals succumbing to the effects of Bacillus anthracis . Hence we believe we are in a position to conclude that neither the blood nor the fluids from the swellings and the lymphatic glands of oxen affected with the disease known as ‘ symptomatic charbon’ by Chabert contains the charbon bacterium nor its germs. We must, then, no longer con¬ sider this affection as a superficial and local indication of systemic anthrax, and we must no longer think that the tumour indicates the seat of entry of the anthrax Bacillus. In the true malignant pustule of man we always find Bacilli present in abundance. These experiments acquire the more importance, since simultaneously nineteen inoculations were made with blood from animals which, in the same neigh¬ bourhood, had died of splenic fever. These invariably led to the death of the subject. Simultaneously M. Thomas made parallel experiments with perfectly fresh fluids — in all cases negative. Having proved thus much, M. Arloing and his collaborators express a hope of some day being in a position to determine whether there is any Bacterial organism characteristic of this affection.” The Becueil of December last gives us some further particulars with regard to the discussion which took place at the Academy des Sciences on the 4th of November between M. Colin and M. Pasteur. The former read a very long memoire , “On the Persistence of Virulent Properties in Carcases and Cadaveric SYNOPSIS OP CONTINENTAL VETERINARY JOURNALS. 85 Debris of Anthrax Animals.” From his ten to twelve years’ research on this subject result the following conclusions : 1. Virulence persists in anthrax blood after two, three, four, or five days, at most, and until this blood, having un¬ dergone decomposition, has become fetid. The rapidity of loss of virulence is proportional to the elevation of the sur¬ rounding atmosphere, and the time since the animal’s death. 2. After eight days it is the exception, even under the most favorable circumstances, for virulence to remain in the carcase. In general it persists no longer than from four to five days in summer and a week in winter. 3. All products from the living animal agree in this respect. Thus, blood, lymph, serous fluids, and pulp from internal organs putrefying lose their virulence at the com¬ mencement of the putrefaction. 4. So thoroughly does removal of the virulence depend on the phenomena of putrid decomposition that all circum¬ stances tending to promote this also hasten the loss of contagion-bearing properties. 5. Conversely, by preventing decomposition without chemical action (as by inducing cold, rigidity, for instance), virulence may be retained for a long time. 6. The charbon virus is destroyed by the action of various chemical agents, alcohol, and astringent salts, even by a temperature of boiling water. Blood simply dried in the open air or in a confined space, and at various temperatures, loses its virulence. 7. The virus is evanescent in excretory products, as dejec¬ tions of anthrax patients. Still, while stating these points so absolutely, Colin hesitates to accept a challenge from Pasteur to lay the matter before a special committee of members of the academy. He divided with his opponent once before on the question of the transmissibility of charbon to fowls, and is hardly yet prepared to again acknowledge himself in error. The arguments he adduces are all nega¬ tive, and of no avail against the positive results of the experiments of M. Pasteur. The latter during the course of the discussion says, “1 can without much difficulty explain the confused criticism to which my work has been subjected, since medicine and surgery are now, as it seemed to me, in a state of crisis and transition. Two cur¬ rents involve them. One doctrine is becoming worn out with age, while another has just been born. The former, with still numerous partisans, is based on the belief in the spontaneous origin of transmissible diseases. The latter is 86 SYNOPSIS OF VETERINARY CONTINENTAL JOURNALS. the theory of germs, of contagium vivum, with all its legi¬ timate deductions. When I hear mentioned this birth of a charbon virus without any serious basis of proof to support it, when in our minutes I read the account of experiments on the subjects with which I deal made without precision, when I see negative results abounding in all sorts of errors brought forward in opposition to positive and demonstrated facts, I say with grief, f Here is still an example of the methods and dogmas of the recent past,’ and I feel myself encouraged to pay to your science, which I love well for its own sake as well as for its wide and beneficent applications, a new tribute of scientific efforts.” The zeal of a provincial veterinary society, in acknowledgment of the valuable bear¬ ings of M. Pasteur’s recent work in the advancement of veterinary science, led it, through its president, to write to the savant in question, offering to him the diploma of vete¬ rinarian. He accepted the offer most cordially, but the Society could do no more in the matter than write to the Societe Centrale requesting co-operation. But to the more important society it seemed inadvisable that such an irregu¬ larity should be permitted even in the case of M. Pasteur, so it was resolved that the proposal could not be adopted ; but to prove the absence of any personal feeling in the matter, by unanimous vote the Societe Centrale de Me- decine Yeterinaire elected M. Pasteur a titular member of their body/ We rather wonder that, with the admirable organisation and unification of veterinary societies recently adopted in France, such an awkward contingency could arise. M. Pasteur has also recently been added to the Con¬ sulting Committee on Epizootics. His presence at the meet¬ ings of this important sanitary body will prove of advantage to his country. Also we note that the same honour has been conferred on a distinguished veterinarian, M. Boutet, of Chartres. M. Bouley shows us how (( history repeats itself” in tracing the position of the charbon question as discussed in the present day by MM. Colin and Pasteur. He recalls the discussion in 1857 on the communicability of glanders of the horse to man. Hayer brought the matter forward in reference to a case of glanders in man which he had under treatment, but Elliotson, a countryman of ours, had pre¬ ceded him in the discovery. Medical authorities, and no¬ tably veterinary pathologists, rallied themselves in a vast phalanx, which threatened to utterly overthrow M. Rayer’s single efforts. M. Barthelemey (Senior), Professor at Alfort, was their eloquent and able leader. An “ enormous mass ” INFECTIVE AND CONTAGIOUS DISEASES. 87 of negative facts was brought forward by them. The Alfort students had never become affected with glanders, though running risk in every form of inoculation from their patients and dissection subjects. However, a medical man of Cha- renton stated that the mortality of the students from a dis¬ ease which he had hitherto considered a peculiar form of putrid fever, but the symptoms were those exhibited by M. Reynal’s patient, was considerable. Here, again, a momen¬ tous question was settled by experimentation, for Urbain Leblanc inserted some pus from the human patient beneath the skin of a horse, which died from acute glanders. We can imagine this history will not be very palatable to anti- vivisectionists. The dispute might have been carried on in theoretical argumentation for years; but one scratch with a lancet, and the death of one horse, saved the lives of, inter alios, numbers of veterinarian students by indicating to them a source of terrible danger. During the past year careful examination of the blood and tissues of men who have died from “ wool-sorters’ disease ” has shown the presence of Bacillus anthracis. The disease is taken from the skins of sheep who have died from some form of anthrax — another proof of the value of the study of comparative pathology. ABSTRACT OF LECTURES, BY DR. W. S. GREEN¬ FIELD, Professor Superintendent of the Brown Institution, ON “ RECENT INVESTIGATIONS IN THE PATHOLOGY OF INFECTIVE AND CONTAGIOUS DISEASES.” SPECIALLY REPORTED. ( Continued from p. 28.) Lecture IV commenced with an enumeration of the synonyms and symptoms of the disease commonly known as “ quarter evil.” For these the lecturer expressed his indebtedness to Mr. Banham, M.R.C.V.S. He then commenced to discuss the ques¬ tion whether this disease is the same as splenic fever. It assumes two forms, one affecting the quarter, the other being of the nature of mycosis, and affecting the intestines. The disease occurs especially in young stock, is most prevalent in the early part of the summer, is more localised, seldom more than one or two animals are attacked, and its communicability by contagion is questionable. Also the post-moriem appearances are some- 88 INFECTIVE AND CONTAGIOUS DISEASES. what different, the principal being a dark-red, frothy, tenacious fluid in the subcutaneous tissue of the affected parts, also blood - exudation, resulting in a disorganised condition of the muscular tissues, which are of a dark-red colour and gangrenous. In serum from the diseased parts are few rods and spores. Yery large spores, resembling those of Bacillus anthracis , were obtained from the heart. The spleen also contained spores, many of them with portions of their filaments still attached. Some of the fluid from the spleen was introduced by inoculation into a guinea-pig. In twenty hours paralysis of the hind extremities occurred, and, later, emphysema of the subcutaneous tissues. On autopsy the subcutaneous serum from the diseased parts was found to contain ordinary Bacteria in a free motile condition ; some were also obtained from the spleen. These displayed none of the charac¬ ters of the anthrax Bacillus ; the blood from the heart contained neither Bacilli nor micrococci. Thus, though the clinical features of the original disease were reproduced, these differ from the results of inoculation either with anthrax or septic matter, for the conditions in this case are marked by putrefaction during life, while examination with the microscope shows Bacterium termo , and not Bacillus anthracis. This is the disease some¬ times known as “ emphysema infectiosum.” We are not yet in a position to decide its true position in relation to splenic fever. The lecturer drew particular attention to the following observa¬ tion made by him : — A white mouse was inoculated with quarter- evil matter ; apparently it recovered from the immediate effects, but a week after swelling of the tail occurred, which assumed a gangrenous character, and extended to the trunk ; swelling of the abdomen occurred, with tumefaction and infiltration of the ab¬ dominal walls from accumulation of an opalescent fluid. Death resulted, and on examination, a few hours after, peculiar flagel¬ lated organisms (illustrated in a diagram), were noted in the peritoneal fluid. They were actively motile, and, with their flagella, not more than ten micro-millimetres in length, with bodies balloon-shaped, changing to a more elongated form, a central (probably contractile) vacuole, with four flagella anteriorly extending from a dark spot (probably an oral aperture), and two posteriorly placed. Dr. Lewis has described fusiform organisms with a cilium at each extremity, which he observed in the blood of rats. These, however, have more numerous processes, and it was thought they may have some pathological value, especially as careful examination of other fluids of the body and of the contents of the stomach and intestines failed to disclose any organisms of a like kind which might have gained accidental entry into the peritoneal fluid. The lecturer next passed to the Cape horse sickness and INFECTIVE AND CONTAGIOUS DISEASES. 89 Loodiana fever. It is known that splenic apoplexy affects horses, and some forms of anthrax in other animals to a certain extent resemble those in the horse. But the exact relation of these disorders to common anthrax is still sub judice. The Cape sickness is enzootic in Natal and Zululand, prevailing especially in hot, damp weather ; it disappears during the dry season ; it is somewhat generally attributed to animals feeding on wet grass . [Mr. Fleming supplied material with which the lecturer experimented on mice.] The principal symptoms are great swelling of the tongue and of the throat; elevation of temperature to 105° or 108°. The disease is extremely fatal, and decomposition sets in very soon after death. The following post-w,ortem appearances were noted : — Some bronchial catarrh and subpleural exudation (these conditions of the lungs constitute a marked and constant feature of the affec¬ tion), inflammation following the course of the bronchi, Bacilli in the exuded matters, blood-vessels of the bronchi sometimes plugged with leucocytes, their submucous tissue thickened, often surrounded by inflammatory or haemorrhagic exudative material ; matter similar to this caused thickening of the pleura. It was observed that the Bacilli occur in numbers only at the seat of commencing inflammation. Some long Bacilli were found in the peritoneal fluid and in the blood. Sometimes the Bacilli seemed to be in the act of passing through the walls of the vessels in all parts ; they seemed to disappear as inflammation became more marked. Thus, though they closely resemble those of splenic fever, they are distinguishable as being not so abundant, more localised, and more slender. They were cultivated to several generations (the various phases being illustrated by diagrams), but no inoculations after culture wrere tried. These culture forms exhibited the long slender character of the Bacillus, also they gave evidence that the organism is a true Bacillus. Spiral chains with great loops were found, but not the masses of filaments, as seen in the farcy Bacillus. It is observable that in all these cases of blood poisoning death often occurs when the lesions are practically inappreciable ; in this disease in none of the organs have Bacilli been observed plugging the capillaries. Probably it is not identical with anthrax, but only allied to it ; the mere presence of Bacilli is not conclusive on the matter of identity, for there are various forms of Bacilli associated with various diseases. With regard to the “ Loodiana fever” the lecturer’s observations have failed for want of properly preserved material. It may be either septicaemia or due to a Bacillus resembling that of anthrax. It may be noted that it occurs under conditions similar to those which originate Splenic and Cape fevers, for Loodianah is a pro- 90 INFECTIVE AND CONTAGIOUS DISEASES. verbially malarial place on the Sutlej, one of the originating tributaries of the Indus. In reference to the organism figured as having occurred in a case of glanders, or rather farcy, the lecturer obtained it from one of the “farcv buds” of a man. There could be but little doubt V as to the nature of his disease, for one of his fellow-horsekeepers died from acute glanders, and he himself exhibited the symptoms of farcy. The swellings on his arm contained an opaque, chyle¬ like fluid, containing many oil globules and minute spore-like bodies. The spores were cultivated in six cells ; of these, two spoiled, while the other four were successful. In the latter, after a few hours, filaments, united into bands, in consequence of their being arranged side by side, appeared ; these were looped at their extremities. A few hours later the masses were broken down and replaced by accumulations of line granules, with only remnants of the original filaments ; from these, long rods ran in various directions, which afterwards broke up into short rods or directly formed spores, the latter separating into pairs, as has been observed in the anthrax Bacillus. By following these spores through several generations they were found sometimes to break up each into four sporules. (Ewart has observed a similar breaking up of spores in anthrax Bacillus, while Toussaint describes the conversion of anthrax Bacillus spores into bulbous joints, from which sporules are formed, which are discharged, and develop into the ordinary rod-like form. These he observed during culture in the serum of a dog.) Theprofessor then stated his opinion that the thorough and ela¬ borate researches of Klein on contagious pneumo-enteritis (“ty¬ phoid fever of pigs ”) have given us the first and, at present, the only admissible instance besides anthrax in which Bacteria have been proved to be actual contagia (see 187 7, ‘Report of the Medical Officer of the Local Government Board’). Though Klein considers this disease analogous with anthrax, it must be considered as more closely allied to acute specific fevers ; the Bacillus closely resembles that of anthrax, but is smaller. The experiments of Klebs and Tommasi on the nature of the specific agent producing malarial fever may be found in Klebs’ Arc/iiv. They consisted in filtering the air of a malarial district, and thus obtaining organised particles ; some were also obtained from the soil. With these they inoculated rabbits, and obtained their Bacillus xnalarise (as figured in diagram). In rabbits inoculated with liquid containing Bacilli, procured from the soil by culture, a fever was produced of the typically intermittent character, the temperature rising to about 41 ’8° C. (complicated experiments were made to ascertain whether the materies morbi exists in the liquid or in the solid portion of the inoculated matter ; thus it was INFECTIVE AND CONTAGIOUS DISEASES. 91 found that the material filtered, when introduced in four times the quantity only gave rise to slight fever). In all the animals, inoculated with the mixed liquid and solid matter, swelling of the spleen with the peculiar production of pigment was found. (A summary of these researches has been published in the Practitioner .) From these researches two questions arise — Was the diseased condition identical with malarial poisoning ? and, Are we justified in concluding that the organism described is specific ? The observers answer the former question in the affirmative, for the disease, like malarial fever, has characteristic intermis¬ sions of temperature, but their temperature charts exhibit varia¬ tion only ranging 1J° C. — 2°C., and the liability to accidental temperature variations in rabbits has already been noted. Also many of their patients died in thirty-six hours, or even in a shorter time, and therefore hardly gave any time for observations. Also they note the characteristic triangular form of the enlarged spleen, but this is often observed in chronic congestion, and the lecturer has remarked it in anthrax. With regard to the peculiar production of pigment, it is too complicated a matter to be discussed here. The only difference between Bacillus anthracis and Bacillus malarias (Klebs and Tommasi) is that the spores are smaller. We cannot, therefore, allow the specificity of this malarial Bacillus, though undoubtedly the organisms produce the disease described in rabbits. Professor Greenfield* then regretted that want of time pre¬ vented him from dealing with many important aspects of his sub¬ ject. He drew attention to the observations of Messrs. Downes and Blunt on the general nature of Bacteria and their life con¬ ditions; of Mr. Watson Cheyne on the occurrence of organisms beneath antiseptic dressings, and also in the tissues of healthy animals ; of Klebs on syphilitic organisms (illustrated by diagrams) ; and several other recent contributions to our knowledge of these minute organisms. He then gave as a resume of his conclusions — 1. That while studying Bacteria in relation to disease we must have regard to the life-history of Bacteria in general. 2. That we must allow that Bacteria are polymorphic, each individual being capable of variation in form in adaptation to surrounding conditions, &c. 3. That forms of Bacteria may be isomorphous, pathogenic forms, for instance, resembling innocent, or other disease -produc¬ ing organisms. 4. That we are not in a position, by simple inspection, to dis¬ tinguish disease-producing Bacteria from forms compatible with health. Also the potency of some Bacteria is acquired as a result of cultivation. Under certain conditions they acquire 92 ON PLANTS IN RELATION TO ANIMALS. the power of setting up changes in the economy constituting disease ; this property they may transmit to their progeny. 3. That pathogenic Bacteria may be considered under three classes : (a) Bacteria of animal decomposition ; the activity of these varies in intensity at the various phases of their development. ( b ) Bacteria of vegetable decomposition ; perhaps Bacillus anthracis is one of these. (c) Bacteria which are true contagia, as the form producing pneumo-enteritis. There is evidence which proves that some other forms are carriers of contagion, and of them some may act simultaneously with the virus wfliich they convey. 6. That there are various forms of blood disease due to Bacteria. The organisms act mechanically or directly on the blood, causing cohesion of blood-corpuscles and thrombosis ; also they may act directly as irritants on connective-tissue corpuscles and epithelial cells. On the evening of Tuesday, 23rd December, Dr. Greenfield exhibited a numerous and very excellent series of microscopic preparations, illustrating the course of lectures just delivered by him, in a highly satisfactory manner. The lesions of Cape fever, anthrax, septicaemia, and pyaemia, together with the Bacteria of these diseases, were well shown by means of stained specimens. The most choice objects were on view in the Lecture Theatre. Here we particularly remarked the flagellated organisms mentioned in the fourth lecture in connection with “ quarter evil,” most of the flagella being perceptible on careful scrutiny. Also the “ Bacillus from a farcy bud,” of which there were several slides. Bacillus anthracis under cultivation was most attractive. This attendance was numerous and highly appreciative, and the intellectual treat was not a little enhanced by the courteous manner in which the professor explained the various objects. ON PLANTS IN RELATION TO ANIMALS. By Professor James Buckman, F.G.S., F.L.S., &c. (Continued from p. 32.) We shall now conclude our notice of the order Ranuncu- lacese, with the mention of facts connected with the following genera : 1. Chelidonium. Celandine. 2. Corydalis. Fumitory, a form of, 3. Fumaria. Fumitory, true. ON PLANTS IN RELATION TO ANIMALS. 93 1. Chelidonium majus. The first of these is the well-known Celandine of the garden and about the homestead, and is one of those herbs known to most dwellers in the country, from the fact that the bright yellow juice which exudes from all parts of the plant when broken is employed as the favourite remedy for warts and other small excrescences. It is also used as an application to remove dimness of vision, which, latter effect was doubtless caused in much the same way as that derived from preparations of opium, which is usually the oculist’s remedy for opacity of the cornea, while the countryman’s cure is the juice of the Celandine. At one time it was a favourite medicine in jaundice. Dr. Johnston says of it : a The juice is very acrid and pun¬ gent, and acts as a purgative when given internally. It was highly commended by some of tbe old writers as a remedy in jaundice and other diseases of the liver ; but its use in those disorders was probably chiefly due to its yellow colour, which in the days of signature medicine was supposed to indicate its value in such complaints. In later times it has been employed as an expectorant, given in very small quantity in wine or water. The dry root and an infusion of the same part are recommended for a like purpose, but the virtues of the plant are probably exaggerated, and its administration in quantity rather dangerous. “ In old times it was a favourite application to warts, and to remove opaque spots from the cornea, and was likewise applied to various cutaneous eruptions. For this purpose the juice was collected and made up into small cakes with honey, or simply dried and moistened with honey and water when used. The active principle of the Celandine is soluble in both water and alcohol ; it is not volatile, though the herb loses much of its acridity in drying. “ This must not be confounded with the lesser Celandine of the herbalists, which was pilewort — Ranunculus Jicaria — whose bright yellow many-leaved flowers ornament the hedge banks and moist places in the early spring, and which was applied by our forefathers as a topical remedy in haemor- rhoidal disease, but probably owed its reputation merely to the form of the tuberous root, as it has only the biting and pungent qualities of most Ranunculaceae.”* The doctrine of signatures which has been so often dwelt on in these notes is one of peculiar interest, and although plants were on this principle often employed in the most empirical manner, yet there is reason to conclude that * * Useful Plants of Great Britain,’ p. 17. LIII. 7 94 ON PLANTS IN RELATION TO ANIMALS. the uses of plants were often discovered, though by means we should now consider not altogether philosophical. It is curious to note that the Chelidonium is found about the homesteads of North America, having been there intro¬ duced as with us. This plant was probably brought to us from Asia, but has doubtless been taken to the States from England. The common name of Celandine , given to our only species, belongs truly to the Ranunculus Jicaria, in which we have another plant renowned for its uses by signature. The Fumariacese are classed as a suborder, consisting of two genera, which may be described as follow : 2. Corydalis. — Cory dal or exotic Fumitories. — Flowers spurred ; fruit a narrow pod containing several seeds. 3. Fumaria. — Fumitory , or Snakeherb. — Flowers spurred. Fruit a small, roundish, green nut, with a single seed. 2. These are well known for three forms : Corydalis solida, bulbous, corydal. „ lutea, yellow ditto. „ claviculata3 white, climbing, ditto. They are found only in gardens or about garden walls ; are perfectly innocuous herbs. They seem to have been introduced for their curiously-shaped and prettily-coloured flowers ; but in these days of carpet bedding they will only find a place in the garden wilderness. 3. Of these Dr. Syme has figured no less than seven forms, namely, Fumaria palddiflora, Borcei, confusa3 muralis, micrantha, officinalis , and Vaillantii. We, however, agree with Bentham, who classes them all under the head of F. officinalis , or common Fumitory, from whom we quote the following : a Common in cultivated and waste places in Europe and Central Asia, disappearing at high northern latitudes, but carried out as a weed of cultivation to many parts of the globe. Abundant in England and southern Scotland, hut decreases much in the north. FI. all summer and autumn. It varies much in the form of the leaf segments, in the size and colour of the flowers (white or red), in the size and shape of the sepals, and in the precise shape of the nuts ; and several distinct species are generally admitted, but they run so much one into another that there is every probability of their being mere varieties.”* # *' Handbook of the British Flora/ p. 75. ON PLANTS IN RELATION TO ANIMALS. 95 All the forms that we meet with appear to be wholly agrarian, growing in every hit of cultivated ground, whether in the field or in the garden ; it is, therefore, highly probable that they have been introduced with foreign seeds, and, therefore, that they may partake of those slight variations which they possess from being natives of different countries and climates. The following notes convey much that is interesting with regard to the genus : Common Fumitory , Common Earth Smoke . In Kent this is often called wax dolls, from the doll- like appearance of the little flowers. This plant is found more or less wherever corn is cultivated. Though a persevering and troublesome weed, it is one the appearance of which every farmer may regard as an indication of good, deep, and rich land — a circumstance not un¬ noticed by England’s greatest poet when speaking of the rich but unproductive soil of France, laid bare and left uncultivated by the horrors of war. He makes the Duke of Burgundy, in the play of “ King Henry V,” to say : “ Why that the naked, poor, and mangled peace, Dear nurse of arts, plenties, and joyful births. Should not, in this best garden of the world, Our fertile France, put up her lovely visage ? Alas ! she hath from France too long been chased, And all her husbandry doth lie on heaps, Corrupting in its own fertility. Her viue, the merry cheerer of the heart, Unpruned dies ; her hedges even pleach’d. Like prisoners wildly overgrown with hair, Put forth disordered twigs ; her fallow leas The darnel, hemlock, and rank fumitory , Doth root upon.” And, again, in “ King Lear/’ Cordelia says : “ Alack ! ’tis he ; why, he was met even now, As mad as the vex’d sea, — singing aloud, Crowned with rank fumiter and furrow weeds, With harlocks, hemlock, nettles, cuckoo-flowers, Darnel and all the idle weeds that grow In our sustaining corn.” The expressed juice of this plant was at one time a favourite remedy with herbalists for skin diseases, and had a reputation as an anti-scorbutic. Mr. T. J. Pettigew has secured an old medical manuscript from the Royal Library at Stockholm, which is traced back to the fourteenth century, and is supposed to be a poetical “ system of health,” composed by the celebrated 96 ON PLANTS IN RELATION TO ANIMALS. physician John of Milan, in which is an account of the manifold virtues of the fumitory, commencing thus : “ Furmiter is erbe, I say, Yt springyth April et in May, In feld, in town, in yard, et gate. Where lond is fat and good in state, Dun red is his flour. Ye erbe smoke lik in colour, Azeyn feuerys cotidian. And azeyn feurys tertyen. And azeyn feurys quarteyn, It is medicyn soueryn.” Burnett, in his e Anatomy of Melancholy/ speaks of it as a plant “ not to be omitted by those who are misaffected with melancholy, because it will much help and ease the spleen/’ Sir John Hill, in his ‘ Herbal/ recommends the leaves of the fumitory to be smoked as a remedy “ for disorders of the head / and in more modern days Dr. Cullen, who paid great attention to the qualities of our native plants, recom¬ mended it to be used in diseases of the liver, and says — “its remarkable virtues, however, are those of clearing the skin of many disorders.” Since his day the use of the fumitory in medicine has been generally abandoned, lingering only among the “simples” of the herbalist in this country, and in the Japanese Pharmacopoeia, if there be one. Clare, one of our old pastoral poets, alludes to its use as a cosmetic thus : — “And Fumitory, too, a name Which superstition holds to fame, Whose red and purple-mottled flowers Are cropped by maids in weeding hours. To boil in water, milk, and whey, Tor washes on a holiday; To make their beauty fair and sleek, And scare the tan from summer’s cheek ; And oft the dame will feel inclined, As childhood’s memory comes to mind, To turn her hook away, and spare The blooms it loved to gather there.” Since that time other and, perhaps, more injurious appli¬ cations have taken the place of this herb in the mysteries of the toilet, for we can scarcely believe that the words of old John Ray the naturalist would be better received now by the votaries of fashion than they were in his own day, when he said — “ No better cosmetics than a strict temper¬ ance and purity, modesty, and humility, a gracious temper and calmness of spirit ; no true beauty without the signa¬ tures of these graces in the very countenance.” PRACTICAL HINTS ON STABLE MANAGEMENT IN INDIA. 97 The use of fumitory as a cosmetic was doubtless founded upon the doctrine of signatures. The smoky hue of the plant was supposed to indicate a disposition to get rid of d ulness, and hence the adoption of fumitory as a remedy for spleen and as a clearer of the countenance. The seeds of the fumitory very unexpectedly yielded to us some curious information. We had a crop of early Warwick peas, which was so visited by the turtle dove — Caluinba turtur — that it was deemed expedient to have the birds shot, as it was thought that otherwise the pea crop would grievously suffer. In this dilemma we deemed it advisable to have the crops and gizzards carefully examined, when lo, and behold, instead of our finding them full of peas, as was expected they would be, not a single pea was found in a dozen of them ; on the contrary , they were all full of the seeds of different forms of fumitory unmixed with any other food. We were very much interested in this discovery, and more especially when we had ascertained from counting that these weed seeds were found in some birds to be over 800. Let no one therefore, in future, glory in the good they do in killing what they have ever deemed the pea-eating dove, for though the dove is by no means bad food, it may be well to consider whether the beauty of the bird, and the good it does, ought not to entitle it to protection. PRACTICAL HINTS ON STABLE MANAGEMENT IN INDIA. A Second Edition, revised and enlarged, of a Lecture written by J. B. W. Skoiilding, Veterinary Surgeon First Class, Royal Horse Artillery, the prototype having been written and delivered by him when in charge of B. F. R. H. A. at Campbellpore, in November, 1875. Meerut, 1878. Introductory Remarks. The majority of those persons who interest themselves in the welfare of the horse will agree that stable management is a subject to every detail of which all who may be trusted with the care of horses should give the strictest attention, and with which owners should make, themselves thoroughly acquainted, since it plays such an important part in preserving the health, and 98 PRACTICAL HINTS ON STABLE MANAGEMENT IN INDIA, thereby ensuring the efficiency, of those useful and willing labourers for man. The wild horse . — Many quote the wild horse, or, as they designate him, the horse in a state of nature, as the most to be envied, and as the healthiest of the equine race ; with these hypothetical assertions I venture to differ, for imagine that wild horses, in common with those tamed, have their full share of discomfort, lameness, deformity, and disease, and, accepting the coarse, under-bred Waler as the specimen or sample of the un¬ tamed class, with which we are most familiar, should not be surprised to find the home-bred animal to be the superior of the two in every particular, and maintain that the life of a horse in a state of domestication, if he be well tended and judiciously managed, will be as enjoyable and his health as perfect as the health of any member of the animal world. Use of the domestic horse. — When we reflect on the number of individuals who live in constant dependence on the horse, some to keep them in health, others for their amusement, while very many are still further indebted to him, he being the actual bread winner for their families and themselves, and bearing in mind also that without him and the rest of his species our armies would become comparatively useless, it should stimulate one and all who have charge of horses, either directly or indirectly, to exert themselves to the utmost to promote the welfare of such invaluable and profitable animals, especially as they are known to be, when stabled, so entirely dependent on their attendants and masters for every necessary and comfort of life. Health essential. — The prime essential for the maintenance of life and for the preservation of health in man are equally neces¬ sary for the well-being of animals; they comprise — pure air, cleanliness, good food, pure water, warmth, and exercise; and the provision of these principles individually with a judicious combination of them as a whole will be found to be of material benefit to the horses or other stock under our care, and to constitute the acme of stable management. a. Pure air — ventilation. — In bringing these requisitions to notice I shall commence writh the first enumerated, pure air.” The numerous contrivances for providing this most important requisite for the preservation of life and health are wrell known, and belong to the art of ventilation. The supply of air in every stable should range from 2000 to 4000 cubic feet per horse, for a deficiency in this particular is one of the most formidable of the foes to successful stable management, but at the same time the ingress of it to the building should be perfectly under control. Plan of stables. — In England the plan on which the majority PRACTICAL HINTS ON STABLE MANAGEMENT IN INDIA. 99 of stables are built ensures this, but in this country it is usual to erect ranges of stabling for troop horses open on both sides, through which the wind rushes without let or hindrance ; and in addition to this mischievous error we find these buildings, as a rule, facing to the east and to the west with each side and end entirely unprotected. Private stables also usually have an eastern or a northern aspect, but these are generally provided with shamps or chicks, wherewith to check any undue influx of winds. Plan of stables — evil effects. — Building stables on this erroneous plan, coupled with the injudicious method of ventila¬ tion resulting therefrom, are, in my opinion, active agents in bringing to maturity those outbreaks amongst horses of the virulent type of fevers met with in India ; for daily experience proves that no great number of animals can possibly preserve their health if constantly exposed to sudden changes of tempera¬ ture, accompanied by the action of a draught, as the occupants of such stables necessarily are whenever a wind may arise. It appears to me that horses properly clothed and cared for would keep their health much better if in the open air during the preva¬ lence of a cold wind than when stabled in such buildings ; for, though it is true they would be more fully exposed to all changes of weather, still, unless picketed under trees, they would escape the draughts to which they are subjected in this class of building. Action of cold . — It is a well-known fact that while a certain degree of cold acts as a tonic, and is exhilarating to the system, an excess of that agent, if its action be long continued, espe¬ cially when in the form of a draught, becomes a most powerful and dangerous depressant, lowering the vital energies to a fearful extent, and by checking the action of that vast and important organ in the economy of life, “ the skin/’ it deranges the work¬ ing of the agents of the circulatory and digestive systems, gives rise to morbid formation in the thoracic and abdominal viscera, and paves the way for attacks of those dire diseases which cause such havoc by death at certain periods of the year amongst animals in this as well as in other parts of the globe. Jjouble stables. — A knowledge of this induces me to point out that stables, if double, i.e. open, and with stalls or standing places for horses on both sides, should most certainly be located on high ground, on a gravelly soil if possible, and in such a position as to secure to them a southern and northern aspect ; they should be lofty and spacious, having thatched roofs, with very deep verandahs, running the entire length, on each side of, and round the ends of the buildings. These verandahs, and the roof of the stable, should be sup- 100 PRACTICAL HINTS ON STABLE MANAGEMENT IN INDIA. ported on iron pillars, by means of which the stables would be rendered less draughty, for the circular iron pillar would other a more limited surface to oppose any gust of wind that might per¬ chance gain entrance to the stable, and thus the piercing draughts occasioned by the square piles of bricks on which the present erections are supported would be avoided. With this object still in view, viz., the annihilation of the draughts, each opening into the verandahs should be furnished with a purdah, made with a reed or cane framework, and this covered with tat or sacking, since this article will be found far more durable, and infinitely less cumbersome, than the ordinary shamp of matting and bamboo ; nor is it so liable to fall on and frighten a horse when the animal may be taken from or brought into the stable. In hanging these purdahs a small space should be left between the upper part of the purdah and the edge of the verandah roof, to allow the passage of a certain volume of air, and they should be dropped, as a rule, only on the windward side and end of the building, leaving one side of the stable generally open. Ridge ventilation with movable louvre boards, should be attached to the roof of the stables, and with these aids the in¬ gress of the air could be regulated, and draughts of either hot, cold, or damp winds avoided, while the spacious verandahs would protect the inmates from the danger and discomfort of prolonged exposure to the action of the sun or rain. Single stables . — The above precaution effectively carried out in double stables would, I affirm, sensibly diminish the annual mor¬ tality amongst the horses in this country ; but I consider stables with stands on one side only, if properly situated, of ample height and width, having a southern aspect, ventilated and protected in the manner already described, with the addition of windows, or air-holes, cut high in the walls over each horse, would be far more healthy than those built on the double plan. Loose boxes. — It would be advisable to allow each quiet troop horse a roomy loose box to live in, instead of tethering him by the head and heels, as troopers, and very many private horses, too, unnecessarily are at the present time ; and in this country, where there is usually ample space to build upon, the cost of these boxes would be very little, if any, in excess of the outlay for the ordinary stables, while the comfort, at least, of the in¬ mates would be secured. IV ant of protection. — I have for many years been deeply im¬ pressed with, and astonished at, the fact that although in India man’s ingenuity is highly taxed, and all his skill brought to bear, to invent and carry into effect schemes and methods for the protection of man and horse against the ills which may possibly PRACTICAL HINTS ON STABLE MANAGEMENT IN INDIA. ] 01 arise through the agency of the intense heat of the climate during those months of the year known as the hot season, yet, strange to relate, those maladies which will inevitably follow sooner or later from undue exposure to cold are either treated as matters devoid of import, or are ignored as completely as if this climate were invariable, and there were no cold season to succeed the hot weather. Change of temperature. — Nor does it seem to be borne in mind that the influence of the extreme heat will have been suffi¬ cient to render those within its range more susceptible to the change of temperature when the cold weather sets in ; while all efforts to bring these effects effectively to notice meet with a sure rebuff. Surely this must be an error fraught with danger to all, for one would imagine the climate of India to be, from its changeability, such as would demand extra care on our parts to protect ourselves and our animals against the baneful effects of cold chills, even during the hot season, when the changes of temperature are so marked and sudden, that although an indi¬ vidual may have been perspiring profusely, and on the verge of suffocation through the intensity of the heat, he may within a very short lapse of time be shivering from the effects of a northerly, or under the deadly blast of that generally acknowledged enemy of man and beast, the “ east wind.” I say u generally ac¬ knowledged,” because some people profess to believe the action of an easterly wind to have a highly beneficial effect on horses exposed to it in this country. This, however, is a mischievous fallacy, for the baneful influence such a wind exercises over the health of horses is so marked that during my service I have been able to tell from which quarter the wind came by the character of the sores affecting patients in hospital, since, if from the east, these sores would be torpid and unhealthy, while the advent of a westerly breeze seemed to revivify and stimulate the most obstinate to healthy action ; nor did the phenomenon escape the notice of others, for the salootrie invariably replied to the inquiry, “ How are the sores this morning ? ” “ Doing well, sir, of course, as of a necessity they should, the wind being in the west;” or vice versa. And with this fresh in my memory I write to expose so dangerous and foolish a dogma as faith in the virtue of the east wind certainly is. (To be continued .) 102 LIFE PHENOMENA : SOME NOTES ON NITELLA, &c. By W. Hastie Kennedy, M.R.C.V.S., Wrexham. If we would examine the phenomena occurring amongst the very low forms of animal and vegetable life, our ideas and views concerning such deeply interesting matter would be materially enriched thereby. We have in such observations a royal road, which appears to be leading on and on, and which, in the not far distant future, bids fair to become of vital importance in aiding us to arrive at some very practical solution of what at present remains a deeply profound mys¬ tery — the mystery of the cause, which produces, and regu¬ lates, and controls vital phenomena. By no means should we be blindly dragged — as I fear too many are — into too implicit confidence in accepting so-called “ modern views” of the cause of these life phenomena — views these which would refer all vital phenomena, whether of animal or vege¬ table life, simply and alone, to an unintelligent and unconscious force agency — to a force agency which has correlations, which is identical with the ordinary physical and chemical forces of our universe — to a force agency which is incom¬ petent to guide and govern itself! which cannot determine results for itself! which cannot determine conscientious and intelligent results ! for it itself is not possessed of these qualities! and which would refer such complicated phenomena to some stray chance, or to some blind and undiscerning fatality ! ! such would be solutions; but surely perfectly unin¬ telligible solutions of the vital question, which, with much vaunted enthusiasm, we find held up to us as truthful facts and realities, would, I feel surely confident, if we would but lay hold of opportunities for ourselves — if we would but deduce observations and opinions for ourselves — be accepted by us as simply resolving themselves into nothing of any greater importance than a heaped mass of extravagant, unfounded views, and conjectural hypotheses, which may suit for the time the assumptive proclivities and Utopian conceptions of their certain philosophic propounders, but which, in so far as modern research — in so far as truthful fact — observation, and experiment has yet favoured us — can be seen by the unbiassed scientist to have no real firm basis of ground whereon to support such conclusions. They would have you reject a truism, that which truthful scientific observation can alone give you, and they would have you LIFE PHENOMENA I SOME NOTES ON N1TELLA, ETC. 103 blindly receive in its stead nothing of any greater importance than an exhumed Lucretian fable — a fabulous hypothesis, which itself once lay buried in the miserable dust of oblivion, as a fallen star, but which now has arisen again, clothed in far greater grandeur and attractiveness, and offered for acceptance as a u modern treasure-trove,” hut surely a doctrine which tells you “ that the mechanical shock of atoms has been the all-sufficient cause of all things,” and which asks you to accept “ that only dead, lifeless, inor¬ ganic atoms, and blind unconscious atomic forces have been and are concerned in the formation of all things living as well as dead,” and that would reject a determining cause or power to determine results, believing rather that unconscious force and unconscious atoms have determined their own destiny, and have made, and moulded, and fashioned them¬ selves, and that they have brought themselves into existence, and have built up by chance circumstances, organic nature in all its ever-resplendent grandeur, with all its order and arrangement, with all its unity of plan and purpose, with all its adaptation of means to end — I say a doctrine which would ask acceptance to such imaginative statements as these, must be one which every student of nature should reject implicitly as not by any means commendable to his views, as a truthful expose of the scientific facts of our time. Ordinary chemical or physical force never surely created life or imparted life. Life surely never emanated from inorganic stuff. Organisms were surely never generated out of chemical materials by the simple action of physical force. Life surely never came into existence, under any circumstances whatever, unless from pre-existing life ; and how any one can ignore or douht a needed agency or power to determine that results should occur in the precise way that they do occur in organic nature apart from and superior to the ordinary correlative physical and chemical force agencies, I am at a loss to know. These assuredly by themselves cannot have the power to do this, for they themselves are dead. They themselves are lifeless. They are themselves governed, and controlled, and directed, and by some power and by some agency surely of much superior worth to themselves, and which can have no co-relations with themselves. Those who may not have had the opportunity of directing their attention to Professor Allman’s address, which he delivered at the August meeting of the British Association, may permit me here to direct their attention to so very able and exhaustive an address ; it bears largely upon the subject matter of this paper, and will be found very fully given in 104? LIFE PHENOMENA : SOME NOTES ON NITELLA, ETC. the August 25th number of Nature. To those interested in biological research his remarks must be of the first interest, for they give so clear and so eminently modernised an expose of those more recent remarkable observations which have been deduced from the study of protoplasm, as seen in the animal and vegetable kingdoms ; and to those who have not as yet taken much interest in these life observations, may I be per¬ mitted to state I feel surely confident his observations, if read, would stir up a deep incentive in their minds to become fully acquainted with the remarkable literature of so interest¬ ing a subject. The phenomena which may be here noticed lie, undoubtedly, at the very root basis of all biological research, and to be able to observe these phenomena, and to make their intimate acquaintance, will amply repay any time spent in so doing, and will give such healthful and lucid views of “ what constitutes life,” which it would be otherwise, by any other means at our hands, impossible to obtain. Professor Allman, in the course of his remarks, refers to Nitella, among others, as a lower vegetable form, 'where some rather interesting life phenomena may be observed ; the whole history of cell life may be observed here, nutrition, and growth, and movement, and reproduction, and those other characteristic life changes which are always present where life is present, may all be observed here. These may not always — indeed, rarely are — to be observed in animal or vegetable cell life. The phenomena may be present, but not always visible to the eye. Here, in Nitella, they may all be observed, and with much marked clearness, showing, simply, yet very decidedly, how needful it is that the animal and vegetable kingdoms alike should both equally demand our careful and earnest study. Nitella belongs to the Characese group of plants — the Chara order; it is a simple, flowerless, leaflless water plant, a frequenter of our ponds and running streams, composed of a distinct stem, branching off* in a whorled manner, sending off at definite points probably eight or ten branches, more or less, these different branchings themselves repeating or not repeating this same process. Nitella is thus a very simple plant, consisting simply of a distinct stem, which gives off similar stem-like branches itself. The stem stalks of Nitella, if examined under a £ microscopic objective, will be found to be composed simply of very large, long, tubular-looking cells, arranged singly, not placed side by side, but one fol¬ lowing the other, a concave end of one cell meeting a convex end of another. It encloses within its cellulose wall certain LIFE PHENOMENA I SOME NOTES ON NITELLA, ETC. ] 05 bodies, these all circulating and moving with much freeness in a transparent and colourless liquid. The cellulose wall has entering into its composition, on its inner side, a number -of small, oval-looking cells, some more ovally lengthened than others, closely arranged side by side ; and if I am correct in this observation you may detect other larger, irregular sided, cell-looking bodies, these apparently interspersed on the outer side of the wall. The cell wall has a green appear¬ ance (due to its contained chlorophyll), and is perfectly transparent, for you may see, and with much marked dis¬ tinctness, circulating within, the cell contents as they are propelled along by the liquid moving protoplasm. The protoplasm in Nitella is not free, it does not emit pseudopodia, but is closely confined within its resisting cell wall, composed of cellulose, completely shutting it up from all direct contact with any external medium. The firm resisting cellulose membrane or wall is a secretion from the active protoplasmic mass within, and may contain a more or less interspersion of limy or siliceous matter ; but this latter condition is more particularly noticeable in Chara than in Nitella. Having now noticed the cellulose wall, permit me to direct attention to the contents of the cell, as seen under a J objective. These will be found to consist of large oil globules, free chlorophyll masses, presenting a cell-like appearance, smaller protoplasmic cell masses, and other granular and solid looking matter, each and all circulating with remarkable freeness ; the circulating matter of one cell does not pass into another, but is confined to that in which it originated. This circulatory process is not due to any inherent property resident within these bodies themselves, but to the active movements of the transparent, and at present scarcely observable, liquid living protoplasm which fills each cell, and which itself carries these bodies with its current. The circulatory movements (although these may not be seen with easy distinctness), sometimes appear to be doubly performed, you may observe an upper and a lower current, to enable you to detect this, careful observation is required ; each current in the main, however, is seen, running up one side of the cell and returning by the opposite side ; the central portion is not wholly without movement, but it is scarcely observable here ; and some of the masses occasionally may be seen to pass from side to side in their course from one end of the cell to the other. This circulatory process normally is performed and carried out with the utmost regularity, but bring some abnormal circumstance into existence, cause the dissecting needle to 106 LIFE PHENOMENA .’ SOME NOTES ON NITELLA, ETC. press firmly upon the cell, and the current, which was flowing so actively and with such regularity, will at once be partially, or it may be wholly, suspended ; remove now again the needle, and gradually the current will be seen to resume its former activity, and circulate freely ; this mechanical pressure does not produce any irritable movements. Bring now the scalpel to bear upon it, cut the delicate cell into two halves, and you will have an observation brought to view of exceeding worth and value — an observation which will enable you to fully realise and see this fact (which has before been alluded to), that the circulatory phenomena in Nitella is in reality and without doubt effected alone by the active transparent protoplasm, although its movements may not have been before demonstrable to you by your microscope. To the uninitiated prior to this division of the cell, the cell masses must have been themselves accepted as the only moving contents; now, however, these masses or cell bodies will be noticed to be stationary, and devoid of active life movement, while the liquid mass of living protoplasm is distinctly to be observed as active and possess¬ ing movement. Immediately upon cutting through the cell a sudden rush of the protoplasm will be observed, and along with it a goodly host of the cell masses and granular contents. These latter are jutted or shot out to a tolerably good distance, whilst the transparent, glairy, tenacious fluid, appearing absolutely homogeneous and entirely devoid of structure — the pro¬ toplasm — will be found more generally encircling and protruding a short distance from the cut surface. Freed from its cellulose imprisonment we might naturally expect an extensive rush and protrusion, but this is not so ; only some small portion of what the cell must contain may be seen to be protruded, and in some instances I find you may only get the protrusion from the one cut surface, the protru¬ sion probably coming away from the most heavily charged portion. The protoplasm gushes out with active, jerky movements, flows in rather a broad stream, and presents a slightly rippled surface ; these irritable, rippling, jerky movements may continue for the space of one minute, less or more, and then they cease. The filmy-looking mass becomes now quite stationary, and takes on a coagulated appearance. Coagulation may set in almost immediately on protrusion in some instances. The other escaped bodies consist of large circular masses of protoplasm, and other smaller circular portions of the same. These showed no signs of movement. The chlorophyll masses are to be seen LIFE phenomena: some notes on nitella, etc. 107 very abundantly. These are masses of protoplasm, per¬ meated by a colouring matter, which under the influence of light presents a green appearance. These chlorophyll cells, immediately on gaining their exit, become changed in appear¬ ance. You may detect very numerous alterations in shape which these cell masses have assumed. Some have jutted-out processes; some retain their circular appear¬ ance ; others lengthen considerably ; others, again, remain circular, and shoot out several very long, delicate, filmy pro¬ cesses ; others may unite ; and others, again, may lose entirely their circular appearance, and all their contents may be seen to be thrown out into one long fihre-looking process, and several of these green chlorophyll cells become transformed into complete oil globules. Very many of them showed a marked similarity to the multi- or bi-polar nerve cells, whose nucleus was absent. Oil globules are also to be seen particularly numerous, and several of these exceedingly large. The majority, immediately upon gaining their exit, take on a roughened, shaggy, dark appearance, and lose their characteristic brightness. They were not noticed to possess this appearance during their confined circulation, and when a drop of water was placed upon the slide this appearance quickly disappeared, and the distinct oil globule again came into view. There were numerous other granular- looking particles noticed, both during circulation and after division of the cell wall. Neither the iarge globular cell masses of protoplasm nor the smaller portions after their exit seemed to alter their form or position in the least, or evince the slightest signs of movement. Similar observations to these may be noticed in numerous other plant forms, in Chara, in Vallisneria, in Anacharis, and in the hairs of certain other plants — notably in the hairs from the flower of Tradescantia virginica , a very common garden plant. The movements of the protoplasm may be noticed here to very great advantage, and the nucleus of the large cells composing these hairs may also be noticed. And in advanced stages of the cell’s existence, where the cell is not now filled with protoplasm, but where only a small quantity is seen to exist, you may notice that several filmy, fibrinous-looking bands of protoplasm proceed from the nucleus here to different parts of the cell wall. The circulatory fluid and contents traversing these routes of protoplasm in a variety of directions, and all, as a rule, tending towards the nucleus, in whatever part of the cell this may be placed. This, again, is a very beautiful and instructive observation. We may thus, you see, obtain 108 LIFE PHENOMENA: SOME NOTES ON NITELLA, ETC. illustrations of life from even such- lowly conditions as these, without it being deemed needful or at all necessary to refer to those higher and more complicated conditions where states of consciousness, and intellect, and reason reign supreme ; and we may find even here ample sufficiency of ground whereby we may support ourselves against the current, and, to the minds of some, the seemingly fascinating opinions of “modern thought.” There is a something intricate and grand in all life phenomena, and, withal, there is a “ something” in such phe¬ nomena which has baffled the wisdom and conceptions of all bygone ages, and which still remains enshrouded with the profoundest mystery. The question still remains un¬ answered. What is the cause ? What is it that could give to that first germ — that nucule of Nitella — which was to reproduce its exact simile, the power to commence its first life activity, and to do so according to a fixed and definite plan ? It must have been directed and guided in this ; it must surely have been controlled and regulated in these activities, or we could never expect to get produced the exact simile. There surely must be no chance agency at work here ! What is it, then, that commences and causes this process to proceed thus, and to proceed thus according to a determined plan, and for a definite purpose, and for the obtainment of definitely defined results ? The process must be carefully, contiifuously, and cautiously maintained, or our exact required simile would not be produced. And what is the cause of all this? Must it still be chance? Or will we give the benefit of the doubt to some blind physical or chemical force to accomplish it all thus? Or must there be a force or power at work, superior to and apart from these ? which could thus guide, and control, and govern for the precise obtainment of precise and definite ends? The nucule, you know, must develop into the full cell, perfect in size, perfect in conditions, perfect in construction, and perfect in appearance; it must have a similar circulatory phenomenon to that of the parent cell enclosed within a similar delicate cellulose wall. No other conditions but these can be accepted. Then cell after cell must be further produced, placed each in their proper situations, and each and all possessing the same required properties One cell must only produce one cell for a certain limited time ; then, at a definite spot, a whorl of cells must be produced, all proceeding from one cell-stem, which, previous to this, had only produced one cell, but which now is caused to produce a whorl. What could cause this change ? These cell- LIFE PHENOMENA : SOME NOTES ON NITELLA, ETC. 109 forming stems must continue on their course, following the example of their parent cell. They must continue on singly for a time, and then change, and must now produce a whorl of cells ; and so on, repeating and repeating, until a com¬ plete specimen of Nitella is to view, suiting exactly and precisely the simile of its parent producer. And what is it that has thus arranged and brought about this exceedingly well-planned and perfectly carried-out process ? and what is it that can always, without any exception whatever, cause the germ or nucule of Nitella to always produce Nitella, and no other plant form. There must surely be a some¬ thing superior and above mere blind physical or chemical force, guiding, and controlling, and directing the carrying out of this definite plan and purpose. It may appear a very simple phenomenon, to watch and notice the egg develop¬ ment of some lower animal organism, and the egg develop¬ ment of a nematode worm may be accepted as a very familiar example. You may well say here that it is apparently nothing more than a blind chance aggregation of molecule to molecule, and granule to granule, that initiates the com¬ mencement process of this simple development. To the naked eye this may appear so, but there is more than this necessary to enable the senses to explain such simple and yet complicated phenomena ; there is more than this surely necessary to satisfy the senses that such is a correct observa¬ tion. There is this seemingly heedless chance aggregation of particle to particle. Then the careful accumulation still further of these, then the aggregation and development of a delicate external filmy cell or egg membrane, then the further advancement of these existent conditions, and all those other important necessary conditions which must necessarily exist until the egg development is completed. Then the seemingly heedless change in form, and position, and character of the granular contents within. Granule here, granule there, some required here, others there ; then the change of these into cell elements ; then the taking of these latter to themselves of certain defined characters and certain defined functions ; then the placing and arranging of these in their proper position for definite ends, and for the further development of the different component parts of the embryo organism. And then, and lastly, the further increase and development of all these varied processes to all complete maturity. I have, as will be seen, casually hurried over these points, but, 1 say again, that even in these lowly organisms there are life phenomena which themselves require more than a heedless chance of aggregation to bring them liii. 8 110 LIFE PHENOMENA : SOME NOTES ON NITELLA, ETC. about. There is a something working for a stated and defined purpose, and with a stated and defined object in view, or those varied phenomena would never be regulated in the precise way that they are, or made to accomplish, without any exception, the precise ends which they do accomplish, and which, we must bear in mind, must also have been in view from the very commencement. If the process is not commenced according to a definite plan, if any flaw happen during the varied changes, if throughout from beginning to end there be any removal from a definite line of action, hour after hour, and day after day, all through the tedious com¬ plicated and lengthened process — why, the definite object in view could never be accomplished. It is accomplished ! And I ask intelligent reason if we are still to accept with any truthful correctness of conclusion, that all that is necessary is but some blind chance circumstance ! or but some blind fortuitous acting and interacting of atom upon atom! dead, lifeless, inorganic atom upon atom, aided, if you like, by some one or other of the ordinary unconscious and unintelligent force agencies, and all or any of those in¬ tricate life phenomena will be accomplished. “ Know ye ! how opens up the seed ! and how the plant up grows ! How soft and green in sweet spring tide, ’tis ripe ere summer’s close ! — How in the downy covert of the swift- winged swallow’s nest, Instinct ! to mother love, expands the gentle creature’s breast ! And how, beneath the shelter of the fragile ovate shell, A winged germ takes life ! one day ! and quits its narrow cell ! Know ye how !” — Deschamp. Will the blind acting of molecule upon molecule do this ? Can these ordain that this shall occur and it does occur ? Can these determine that this precise result is to he ob¬ tained and it is obtained ? Or will the assistance of physical or chemical force, acting even in unison, bring these things about, that such and such results shall occur, in the precise way they do occur, and accomplish the precise plan and purpose and fulfilment, that we know is always accom¬ plished, and which is ever needful for the correct building up and maintaining of all vegetable and animal life. We say no ! We say that these forces can never do this in themselves, because we see that they have never been known to be capable of controlling, and guiding, and directing their ownselves, or of determining themselves in any manner whatever, according to plan, or for any definite purpose, or for the accomplishment of any definite object in view. No where in the inorganic world do we find such results as these accomplished. Life must ever come from pre-existing life ! LIFE PHENOMENA : SOME NOTES ON NITELLA, ETC. Ill and life must ever first act upon matter before matter can take part in life. Surely, you will not give adherence to