THE LIBRARY OF THE UNIVERSITY OF CALIFORNIA PRESENTED BY PROF. CHARLES A. KOFOID AND MRS. PRUDENCE W. KOFOID ZOONOMIAs O R, THE LAWS OF ORGANIC LIFE. VOL. I. BT ERASMUS DARWIN, M.D.JF.R.S. AUTHOR OF THE BOTANIC GARDEN. Principio coelum, ac terras, campofque liquentcs, .Lucentemque globum lunas, titaniaque ailra, Spiritus intus alit, totamque infufa per artus Mens agitat molem, et magno fe corpore mifcet. ViRG.-ffin.vL Earth, on whofe lap a thoufand nations tread, And Ocean, brooding his prolific bed, Night's changeful orb, blue pole, and filvery zones, Where other worlds encircle other funs, One Mind inhabits, one diffufive Soul Wields the large limbs, and mingles with the whole. DUBLIN: PRINTED FOR B. DUGDALE, DAME-STREET. Cl MB ) X at 1/1 J- o--i M ,»:^- 1 ! I DEDICATION. JL O the candid and ingenious Members of the College of Phyficians, of the Royal Philofophical Society, of the Two Univerfities, and to all thofe, who ftudy the Operations of the Mind as a Science, or who praftife Medicine as a Profeffion, the fub- fequent Work is, With great Refpeft, N. Inscribed by THE AUTHOR. DERBY, May i, 1794. .k o 1 1 : orbos. ; ^ EB M. 9* '!<> tnob«w!'P CONTENTS. Preface. i SECT. I. Of Motion. 5 II. Explanations and Definitions. 7 III. The Motions of the Retina demonftrated by Experiments J 5 IV. Laws of Animal Caufation. 3 2 V. Of the four Faculties or Motions of the Senforium. 34 VI. Of the four Cla/es of Fibrous Motions. 36 VII. Of Irritative Motions. 38 VIII. Of Senfttive Motions. 43 IX. Of Voiitntary Motions. 46 X. Of Affbciate Motions. 50 XI. Additional Observations on the Senforlal Powers. 54 XII. Of Stimulus, Senforial Exert ian, and Fi- brous Contraction. 62 XIII. Of Vegetable Animation. 106 XIV. Of the Production of Ideas. 1 13 XV. Of the Cla/es of Ideas. 1 3 5 XVI. Of Inftincl. 145 XVII. The Catenation of Animal Motions. 2 2 1 XVIII. Of Sleep. 235 XIX. Of Reverie. 260 SECT. VI CONTEMPTS. SECT. XX. XXI. XXII. XXIII. XXIV. XXV. XXVI. XXVIL XXVIII. XXIX. XXX. XXXI. XXXII. XXXIII. XXXIV. XXXV. XXXVI. XXXVIII. XXXVIII. XXXIX. XL* Of Vertigo. 268 Of Drunkennefs. 283 Of Propenfity to Motion. Repetition. Imitation. 293 Of the Circulatory Syftem. 304 Of the Secretion of Saliva, and of Tears. And of the Lacrymal Sack. 3 1 2 Of the Stomach and Intejiines. 320 Of the Capillary Glands, and of the Membranes. 333 Of Hemorrhages. 338 The Paralyfis of the Lacleals. 346 The Retrograde Motions of the Abforbent Veffels. 351 The Paralyfis of the Liver. 40 1 Of Temperaments 408 Difeafes of Irritation, of Senfation. of Volition. — tf AJficiation. The Periods of Difeafes. Of Digeftion, Secretion, Nutrition. 447 474 502 Of the Oxygenation of the B, Lungs and Placenta, Of Generation. Of Ocular Speclra. n 525 the 533 542 605 Additional Obfervations on Vertigo, referred to n Seft. ^X. Page 275, Line 2. 640 TO TO ERASMUS DARWIN, ON HIS WORK INTITLED Z O O N O M I A. By DEWHURST BILS BORROW. HAIL TO THE BARD! who fung, from Chaos hurPd How funs and planets forra'd the whirling world ; How fphere onfphere Earth's hidden ftrata bend, And caves of rock her central fires defend ; Where gems new-born their twinkling eyes unfold, 5 And young ores (hoot in arborefcent gold. How the fair Flower, by Zephyr woo'd, unfurls Its panting leaves, and waves its azure curls ; Or fpreads in gay undrefs its lucid form To meet the fun, and (huts it to the ftorm ; 10 While in green veins impaffion'd eddies move, And Beauty kindles into fire and love. How the firft embryon-fibre, fphere, or cube, Lives in new forms — a line — a ring — a Lube ; Clofed in the womb with limbs unfinim'd laves, I j Sips with rude mouth the falutary waves ; Seeks round its cell the fanguine ftreams, that pafs, And drinks with crimfon gills the vital gas ; Weaves with foft threads the blue meandering vein, The heart's red concave, and the filver brain ; 20 Leads the long nerve, expands the impatient fenfe, And clothes in filken (kin the nafcent Ens. Erewhile, emerging from its liquid bed, It lifts in gelid air its nodding head ; The light's firft dawn with trembling eyelid hails, 25 With lungs untaught arrefts the balmy gales ; Tries its new tongue in tones unknown, and hears The ftrange vibrations with unpraclifed ears; viii TO ERASMUS DARWIN. Seeks with fpread hands the bofom's velvet orbs, With clofing lips the milky fount abforbs ; 3© And, as comprefs'd the dulcet ftreams diftil, Drinks warmth and fragrance from the living rill ;— Eyes with mute rapture every waving line, Prints with adoring kifs the Paphian fhrine, A nd learns erelong, the perfect form confefs'd, 35 Ideal Beauty from its mother's breaft. Now in ftrong lines, with bolder tints defign'd, You fketch ideas, and portray the mind ; Teach how fine atoms of impinging light To ceafelefs change the vifual fenfe excite ; 40 While the bright lens collects the rays, that fwerve, And bends their focus on the moving nerve. How thoughts to thoughts are link'd with viewlefs chains, Tribes leading tribes, and trains purfuing trajns ; With fhadowy trident how Volition .guides, 45 Surge after furge, his intellectual tides ; Or, Qiieen of Sleep, Imagination roves -^ With frantic Sorrows, or delirious Loves. Go on, O FRIEND ! explore with eagle-eye ; Where wrapp'd in night retiring Caufes lie : 50 Trace their flight bands, their fecret haunts betray. And give new wonders to the beam of day ; Till, link by link with ftep afpiring trod, You climb from NATURE to the throne of GOD. So faw the Patriarch with admiring eyes 55 From earth to heaven a golden ladder rife ; jnvolv'd in clouds the myfticfcale afcends, And brutes and angels crowd the diftant ends. Trtn. Col. Cambridge, Jan. I, 1794. REFERENCES TO THE WORK. Butane Garden, Part I. Line 1 8. Seft. XVI. a. and XXXVIII. Line i. " """"" 3» 4-. — — • 5« Canto I. 1. joj. IV 1. 402. I. 1. 140. nr. i. 401. 26. — 36.' 38- XVI. 4. XVI. 4. XVI. 6. ——III. and VII. 8. — — • Q. IV. 1. 452. i. i. 14. 44- XVJII. 17. s 45. XVII. 3. 7. Zconomia. 47- 50. XVIII. 8. Xx XIX. 4 g. 12. Seft. XIII. XXXIX. the Motte. 13. XXXIX. 4. I. 54- XXXIX. 8. PREFACE. JL H E purport of the following pages is an en- deavour to reduce the fa£b belonging to ANIMAL LIFE into clafles, orders, genera, and fpecies ; and, by comparing them with each other, to unravel the theory of difeafes. It happened, perhaps unfortu- nately for the inquirers into the knowledge of difeafes, that other fciences had received improve- ment previous to their own ; whence, inttead of comparing the properties belonging to animated na- ture with each other, they, idly ingenious, bufied themfelves in attempting to explain the laws of life by thofe of mechanifm and chemiftry ; they confi- dered the body as an hydraulic machine, and the fluids as palling through a feries of chemical changes, forgetting that animation was its eflential charac- teriftic. The great CREATOR of all things has infinitely diverfified the works of his hands, but has at the fame time (lamped a certain fimilitude on the fea- tures of nature, that demonftrates to us, that the 'whole is one family of one parent- On this fimilitude i$ founded ail rational analogy ; which, fo long as it is concerned in comparing theeffemial properties of bodies, leads us to many and important difcoveries ; but when with licentious activity it links together objects, otherwife difcordant, by fome fanciful fimi- litude 5 it may indeed colled ornaments for wit B and * PREFACE. and poetry, but philofophy and truth recoil from its combinations. The want of a theory, deduced from fuch ftrict analogy, to' conduct the practice of medicine, is la- mented by its profeffors ; for, as a great number of unconnected facts are difficult to be acquired, and to be reafoned from, the art of medicine is in many inftances lefs efficacious under the direction of its wifeft practitioners ; and by that bufy crowd, who either boldly wade in darknefs, or are led into end- lefs error by the glare of falfe theory, it is daily practifed to the deftruction of thousands ; add to this the unceafing injury which accrues to the pub- lic by the perpetual advertifements of pretended noftrums ; the minds of the indolent become fuper- flitioufly fearful of difeafes, which they do not la- bour under ; and thus become the daily prey of fome crafty empiric. A theory founded upon nature, that mould bind together the fcattered facts of medical knowledge, and converge into one point of view the laws of organic life, would thus on many accounts contri- bute to the intereil of fociety. It would capacitate men of moderate abilities to practife the art of healing with real advantage to the public ; it would enable every one of literary acquirements to dif- tinguifh the genuine difciples of medicine from thofe of boaftful effrontery, or of wily addrefs ; and would teach mankind in fome important fitua- tions the knowledge of the?nfelves. There are fome modern practitioners, who de- claim againil medical theory in general, not confi- dering that to think is to theorize ; and that no one can direct a method of cure to a perfon labouring under difeafe without thinking, that is, without theorizing ; and happy therefore is the patient, whofe phylician poffefles the bed theory. The PREFACE. 3 The words idea, perception, fenfation, recollec- tion, fuggeftion, and aflbciation, are each of them ufed in this treatife in a more limited fenfe than in the writers of metaphyfic. The author was in doubt, whether he mould rather have fubftituted new words inftead of them ; but was at length of opinion, that new definitions of words already in ufe would be lefs burthentbme to the memory of the reader. A great part of this work has Iain by the writer above twenty years, as fome of his friends can tef- tify : he had hoped by frequent revilion to have made it worthy the acceptance of the public ; this however his other perpetual occupations have in part prevented, and may continue to prevent, as long as he may be capable of reviling it ; he therefore begs, of the candid reader to accept of it in its prefent flate, and to excufe any inaccuracies of expreffion, or of conclufion, into which the intricacy of his fubjecl:, the general imperfection of language, or the frailty he has in common with other men, may have betrayed him ; -and from which he has not the vanity to believe this treatife to be exempt. B 2 ZOONOMIA, Z O O N O M I A. SECT. L OF MOTION. JL H E WHOLE OF NATURE may be fuppofed to conlift of two eflences or fubftances ; one of which may be termed fpirit, and the other matter. The former of thefe poffeffes the power to commence or produce motion, and the latter to receive and communicate it. So that motion, confidered as a caufe, immediately precedes every effect ; and, confidered as an effect, it immediately fucceeds every caufe. The MOTIONS OF MATTER may be divided into two kinds, primary and fecondary. The fecondary motions are thofe which are given to or received from other matter in motion. Their laws have been fuccefsfully inveftigated by phiiofophers in their treatifes on mechanic powers. Thefe motions are diftinguiftied by this circumftance, that the velocity multiplied into the quantity of matter of the body acted upon is equal to the velocity multiplied into the quantity of matter of the acting body. The primary motions of matter may be divided into three claffes, thofe belonging to gravitation, to chemiftry, and to life ; and each clafs has its peculiar laws. Though thefe three claffes include the motions of folid, liquid, and aerial bodies j there 6 OFMOTION. SECT. I. there is neverthelefs a fourth divifion of motions ; I mean thofe of the fuppofed ethereal fluids of mag- netifm, electricity, heat, and light ; whofe proper- ties are not fo well inveiligated as to be claffed with fufficient accuracy. ift. The gravitating motions include the annual and diurnal rotation of the earth and planets, the flux and reflux of the ocean, the defcent of heavy- bodies, and other phenomena of gravitation. The unparalleled fagacity of the great NEWTON has de- duced the laws of this clafs of motions from the iimple principle of the general attraction of matter. Thefe motions are diftinguiftied by their tendency to or from the centers of the fun or planets. id. The chemical clafs of motions includes all the various appearances of chemiftry. Many of the fads, which belong to thefe branches of fcience, are nicely alcertained, and elegantly clafled ; but their laws have not yet been developed from fuch fimple principles as thofe above-mentioned ; though it is probable, that they depend on the fpecific attracti- ons belonging to the particles of bodies, or to the difference of the quantity of attraction belonging to the fides and angles of thofe particles. The che- mical notions are diftinguifhed by their being gene- rally attended with an evident decompolition or new combination of the active materials. 3^/. The third clafs includes all the motions of the animal and vegetable world ; as well thofe of the veffels, which circulate their juices, and of the rnufcles, which perform their locomotion, as thofe of the organs of fenfe, which conftitute their ideas. Thib laft clafs of motion is the fubject of the fol- lowing pages ; which, though confcious of their many imperfections, 1 hope may give fome pleafure to the patient reader, and contribute fomething to the knowledge and to the cure of difeafes. SECT. SE«T. II. DEFINITIONS* 7 SECT. II. i. EXPLANATIONS AND DEFINITIONS. I. Outline of the animal economy . — II. i. Ofthejerifo- rium. 2. Of the brain and nervous medulla. 3. A nerve. 4. A mufcular fibre. 5. The immediate organs of fenfe. 6. "The external organs of ' fenfe. 7. An idea or fenfual motion. 8. Perception. 9. Sen- fation. 10 Re collection and fuggeft ion. n. Habit, caufation> affbciation, catenation. 12. Reflex ideas. 13. Stimulus defined. As fome explanations and definitions will be neceffary in the profecu- tion of the work, the reader is troubled with them in this place, and is intreated to keep them in his mind as he proceeds, and to take them for granted, till an apt opportunity occurs to evince their truth ; to which I /hall premife a very fhort outline of the animal economy. I. — i. THE nervous fyftem has its origin from the brain, and is diflributed to every part of the body. Thofe nerves, which ferve the fenfes, prin- cipally arife from that part of the brain, which is lodged in the head ; and thofe, which ferve the purpofes of mufcular motion, principally arife from that part of the brain, which is lodged in the neck and back, and which is erroneoufly called the fpi- nal marrow. The ultimate fibrils of thefe nerves terminate in the immediate organs of fenfe and mufcular fibres, and if a ligature be put on any part of their paflage from the head or fpine, all motion and perception ceafe in the parts beneath the liga- ture. a. The * DEFINITIONS. SECT. II. i. 2. The longitudinal mufcular fibres compofe the locomotive mufcles, whofe contractions move the bones of the limbs and trunk, to which their extre- mities are attached. The annular or fpiral mufcular fibres compofe the vafcular mufcles, which confti- tute the inteflinal canal, the arteries, veins, glands, and abforbent veffels. 3. The immediate organs of fenfe, as the retina of the eye, probably con fifl of moving fibrils, with a power of contraction lirnilar to that of the larger mufcles above defcribed. 4. Tiie cellular membrane confifts of cells, which refemble thofe of a fponge, communicating with each other, and connecting together all the other parts of the body. 5. The arterial fyfte'tn confifts of the aortal and the pulmonary artery, which are attended through their whole courfe with their correfpondent veins. The pulmonary artery receives the blood from the right chamber of the heart, and carries it to the mi- nute extenfive ramifications of the lungs, where it is expofed to the action of the air on a furface equal to that of the whole external fkin, through the thin itioift coats of thofe veffels, which are fpread on the air-cells, which conftitute the minute terminal ra- mificatitihs of the wind pipe. Here the blood changes its colour from a dark red to a bright fear- let. 'It is then collected by the branches of the pul- monary vein, and conveyed to the left chamber of the heart. 6. The aorta is another large artery, which re- ceives the'blood from the left chamber of the heart, after it has been thus aerated in the lungs, and con- veys it by afcending and defcending branches to every other part of the fyftem ; the extremities of this artery terminate either in glands, as the falivary glands, lacrymal glands, &c. or in capillary veflels, which are probably lefs involuted glands \ in thefe fome SECT. II. i. DEFINITIONS. 9 foii.-e fluid, as faliva, tears, perfpiratlon, are fepa- rated from the blood ; and the remainder of the blood is abfoibed or drank up by branches of veins CTrefpondent to the branches of the artery ; which are fu mimed with valves to prevent its return ; and is thus carried back, after having again changed its colour to a dark red, to the right chamber of the heart, The circulation of the blood in the liver differs from this general fyftem ; for the veins which drink up the refluent blood from thole arteries, which are fpread on the bowels and mefentery, unite into a trunk in the liver, and form a kind of artery, which is branched into the whole fuhltance of the liver, and is cahed the vena portarum ; and from which the bile is feparated by the numerous hepatic glands, which constitute that vifcus. 7. The glands may be divided into three fyftems, the convoluted glands, fuch as thofe above defcribed, which feparate bile, tears, faliva, &c. Secondly, the glands without convolution, as the capillary vef- fels, which unite the terminations of the arteries and veins ; and feparate. both the mucus, which lubri- cates the cellular membrane, and the perfpirable matter, which preferves the Ikin moift and flexible. And thirdly, the whole abforbent fyftem, confining of the lacleals, which open their mouths into the ftomach and inteflines, and of the lymphatics, which open their mouths on the external furface of the body> and on the internal linings of all the ceils of the cellular membrane, and other cavities of the body. Thefe lacteal and lymphatic veflels are furnifhf d with numerous valves to prevent the return of the fluids, which they abforb, and terminate in glands, called lymphatic glands, and may hence be confi- dered as long necks or mouths belonging to thefe glands. To thefe they convey the chyle and mucus, with a part of the perfpirable matter, and atmof- pherk moifture ; all which, after having pafled through io DEFINITIONS. SECT. II. 2, through thefe glands, and having fuffered feme change in them, are carried forward into the blood, and lupply perpetual nourifhment to the fyftem, or replace its hourly wafte. 8. The ftomach and inteftinal canal have a con- flant vermicular motion, which carries forwards their contents, after the la&eals have drank up the chyle from them -, and which is excited into aclion by the ftimulus of the aliment we fwallow, but which becomes occafionally inverted or retrograde, as in vomiting, and in the iliac paffion. II. i. The wordfen/brium in the following pages is deligned to exprefs not only the medullary part of the brain, fpinal marrow, nerves, organs of fenfe, and of the mufcles ; but alfo at the fame time that living principle, or fpirit of animation, which re- iides throughout the body, without being cogniza- ble to our fenfes, except by its effects. The changes which occafionally take place in the fenforium, as during the exertions of volition, or the fenfations of pleafure or pain, are termed fen/or ial motions. 2» The fimilarity of the texture of the brain to that of the pancreas, and fome other glands of the body, has induced the inquirers into this fubject to believe, that a fluid, perhaps much more fubtile than the eleclric aura, is feparated from the blood by that organ for the purpofes of motion and fenfa- tion. When we recollect, that the eleclric fluid it- ielf is actually accumulated and given out volunta- rily by the torpedo and the gymnotus ele&ricus, that an electric (hock will frequently ftimulate into motion a paralytic limb, and laftly that it needs no perceptible tubes to convey it, this opinion feems not without probability ; and the fingular figure of the brain and nervous fyftem feems well adapted to dHiribute it over every part of the body. For the medullary fubftanceof the brain not only occupies the cavities of the head and fpine, but pat ics SECT. II. 2. DEFINITIONS. n fes along the innumerable ramifications of the nerves to the various mufcles and organs of fenfe. In thefe it lays afide its coverings, and is intermixed with the flender fibres, which conftitute thofe muf- cles and organs of fenfe. Thus all r(iefe diftant ra- mifications of the fenforium are united at one of their extremities, that is, in the head and fpine ; and thus theie central parts of the fenforium con- ftitute a communication between all the organs of fenfe and mufcles. 3. A nerve is a continuation of the medullary fub- ftance of the brain from the head or fpine towards the other parts of the body, wrapped in its proper membrane. 4. The mufculdr fibres are moving organs inter- mixed with that medullary fubftance which is con- tinued along the nerves, as mentioned above. They are indued with the power of contraction, and are again elongated either by antagonift mufcles, by circulating fluids, or by elaftic ligaments. So the mufcles on one fide of the fore-arm bend the fingers by means of their tendons, and thofe on the other fide of the fore-arm extend them again. The arte- ries are diftended by the circulating blood ; and in the necks of quadrupeds there is a ftrong elaftic li-, gament, which aflifts the mufcles, which elevate the head, to keep it in its horizontal pofition, and to raife it after it has been depreffed. 5. The immediate organs of fenfe confift in like manner of moving fibres enveloped in the medul- lary fubftance above mentioned ; and are erroneouf- ly fuppofed to be fimply an expanfion of the ner- vous medulla, as the retina of the eye, and the rete mucofum of thefkin, which are the immediate organs of viiion, and of touch. Hence when \ve fpeak of the contractions of the fibrous parts of the body, we fhall mean both the contractions of the mufcles. 12 DEFINITION S, SECT. II. i. mufcles, and thofe of the immediate organs of fcnfe. Thefejibrous motions are thus dittinguifhed from the fenforial motions above mentioned. 6. The external organs of fenfe are the coverings of the immediate organs of fenfe, and are mecha- nically adapted for the reception or tranfmiffion of peculiar bodies, or of their qualities, as the cornea and humours of the eye, the tympanum of the ear, the cuticle of the fingers and tongue. 7. The word idea has various meanings in the writers of metaphyfic : it is here ufed limply for thofe notions of external things, which our organs of fenfe bring us acquainted with originally ; and is defined a contraction, or motion, or configuration, of the fibres, which conftitute the immediate organ of fenfe ; which will be explained at large in an- other part of the work. Synonymous with the word idea, we mall fometimes ufe the words fenfual mo- tion in contradiftinction to mufcular motion. 8. The word perception includes both the action of the organ of fenfe in confequence of the impact of external objects, and our attention to that ac- tion ; that is, it expreffes both the motion of the organ of fenfe, or idea, and the pain or pleafure that fucceeds or accompanies it. 9. 1 he pleafure or pain which neceffarily accom- panies all thofe perceptions or ideas which we at- tend to, either gradually fubfides, or is fucceeded by other fibrous motions. In the latter cafe it is termedy^vT/tf//^, as explained in Sect. V. 2, and VI. 2. — The reader is intreated to keep this in his mind, that through all this treatife the word fenfation is ufed to exprefs pleafure or pain only in its active Hate, by whatever means it is introduced into the fyftem, without any reference to the ftimulation of external objects. 10. The vulgar ufe of the word memory is too unlimited for our purpofe : thofe ideas which we voluntarily SECT. II. 2. , DEFINITIONS. 13 voluntarily recall are here termed ideas of recollefti- cn, a?, when we will to repeat the alphabet back- wards. And thofe ideas which are fuggefted to us by preceding ideas are here termed ideas of Juggejl- ion, as whilft we repeat the alphabet in the ufual or- der ; when by habits previoufly acquired B is fug- gefted by A, and C by B, without any effort of deliberation. 1 1. The word affectation properly fignifies a fociw- ety or convention of things in fome refpects iirnilar to each other. We never fay in common language, that the effect is affociated with the caufe, though they neceffarily accompany or fucceed each other. Thus the contractions of our mufcles and organs of fenie may be faid to be affociated together, but can- not with propriety be faid to be affociated with irri- tations, or with volition, or with fenfation ; becaufe they are caufed by them, as mentioned in Sect. IV. When fibrous contractions fucceed other fibrous con- tractions, the connection is termed aff&ciation ; when fibrous contractions fucceed fenforlal motions, the connection is termed caufation ; when fibrous and fenforial motions reciprocally introduce each other in progrefiive trains or tribes, it is termed catenation of animal motions. All thefe connections are faid to be produced by habit \ that is, by frequent repe- tition. 1 2. It may be proper to obferve, that by the un* avoidable idiom of our language the ideas of per- ception, of recollection, or of imagination, in the plural number fignify the ideas belonging to percep- tion, to recollection, or to imagination ; whilft the idea of perception, of recollection, or of imagina- tion, in the fingular number is ufed for what is termed " a reflex idea of any of thofe operations of the fenforium." 13. By the wordflimulus is not only meant the application of external bodies to our organs of fenfe and 14 DEFINITIONS. SECT. II.*. and jnufcular fibres, which excites into action the fenforial power termed irritation ; but alfo pleafurc or pain, when they excite into action the fenforial power termed fenfation ; and defire or averfion, when they excite into action the power of volition ; and laftly, the fibrous contractions which precede affectation ; as is further explained in Sect, XII. 2. i. SECT. SECT. III. i. MOTIONS OF THE RETINA. SECT. III. THE MOTIONS OF THE RETINA DEMONSTRATED BY EXPERIMENTS. I. Of animal motions and of ideas. II. The fibrous ftruclure of the retina. III. The aftivity of the re- tina in vifion. i . Rays of light have no momentum. 2. Objects long viewed become fainter. 3* Spectra of black objecls become luminous. 4. Varying fpeclra from gyration. 5. From long injpedion of various colours. IV. Motions of the organs of fenfe conftitute ideas, i. Light from prejjing the eye-ball, and found from the pulfation of the carotid artery. 2. Ideas in Jleep mif taken for perceptions. 3. Ideas of imaginati- on produce pain andjicknefs like fenfations. 4. When the organ of fenfe is deftroyed, the ideas belonging to that fenfe per ifh. V. Analogy between mufcular mo- tions and Jenfual motions, or ideas, i. cfihey are both originally excited by irritations. 2. And ajjociated to- gether in the fame manner. 3. Both aft in nearly the fame times. 4. Are alike ftrengthened or fatigued by exercife. 5. Are alike painful from inflammation. 6. Are alike benumbed by comprejjion. 7. Are alike liable to paralyfis. 8. To convulfion. 9. To the influence of old age. VI. Objections anfwered. i . Why we cannot invent new ideas, i. If ideas refemble exter- nal objefls. 3. Of the imagined fenfation in an ampu- tated limb. 4. /ibftratl ideas. VII. What are ideas, if they are not animal motions ? BEFORE the great variety of animal motions can be duly arranged into natural clafles and orders, it is neceflary to fmooth the way to this yet uncon- quered field of fcience, by removing fome obftacles C which *6 MOTIONS OF THE RETINA. SECT. III. i. which thwart our paffage. I. To demonftrate that the retina and other immediate organs of fenfe pof- fefs a power of motion, and that thefe motions con- flitute our ideas, according to the fifth and feventh of the preceding affertions, claims our firft attenti- on. Animal motions are diftinguiflied from the com- ttiunicated motions, mentioned in the firft feclion, as they have no mechanical proportion to their caufe; for the goad of a fpur on the Ikin of a horfe fhall induce him to move a load of ha^. They differ from the gravitating motions there mentioned, as they aj*e exerted with equal facility in all directions, and they differ from the chemical clafs of motions, becaufe no apparent decompofitions or new combi- nations are produced in the moving materials. Hence, when we fay, animal motion is excited by irritation, we do not mean that the motion bears any proportion to the mechanical impulfe of the ilimulus ; nor that it is affected by the general gra- vitation of the two bodies ; nor by their chemical properties, but folely that certain animal fibres are excited into action by fomething external to the * moving organ. In this fenfe the ftimulus of the blood produces the contractions of the heart ; and the fubftances we take into our ftomach and bowels irritate them to perform their neceffary functions. The rays of light excite the retina into animal motion by their ftimuius ; at the lame time that thofc rays of light themfeives are phyfically converged to a focus by the inactive humours of the eye. The vibrations of the air ftirnulate the auditory nerve into animal ac- tion ; while it is probable that the tympanum of the ear at the fame time undergoes a mechanical vi- bration. To Seer. III. i. MOTIONS OF THE RETINA. 17 To render this circumftance more eafy to be com- prehend e 1 motion may be defined to be a variation of fgure ; for the whole univerfe may be confidered ag one rhino; pofTeffmg a certain figure ; the motions of any of its parts are a variation of this figure of the whole : this definition of motion will be further ex- plained in Section XIV. 2. 2. on the production of ideas. Now the motions of an"organ of fenfe are a fuc- cefllon of configurations of that organ ; thefe con- figurations fucceed each other quicker or flower ; and whatever configuration of this organ of fenfe, that is, whatever portion of the motion of it is, or has ufually been, attended to, conftitutes an idea* Hence the configuration is not to be confidered as an effect of the motion of the organ, but rather as apart or temporary termination of it; and that, whether a paufe fucceeds it, or a configuration im- mediately takes place. Thus when a fucceffion of moving objects are prefented to our view, the ideas of trumpets, horns, lords and ladies, trains and canopies, are configurations, that is, parts or links of the fuccellive motions of the organ of vifion. Thefe motions or configurations of the organs of fenfe differ from the fenforial motions to be defcrib- ed hereafter, as they appear to be (imply contrac- tions of the fibrous extremities of thofe organs, and in that refpect exactly referable the motions or con* tractions of the larger mufcles, as appears from the following experiment. Place a circular piece of red filk about an inch in diameter on a (heet of white paper in a ftrong light, as in Plate I. — look for a minute on this area, or till the eye becomes fome- what fatigued, and then, gently clofing your eyes, and (hading them with your hand, a circular green area of the fame apparent diameter becomes vifible in the clofed eye. This green area is the colour reverfe to the red area, which had been previoufly C 2 infpected, J8 MOTIONS OF THE RETINA. SECT. III. j. infpefted, as explained in the experiments on ocular fpeftra at the end of the work, and in Botanical Garden, P. I. additional nore, No. I. Hence it ap- pears, that a part of the retina, which had been fa- tigued by contraction in one direction, relieves it- ielf by exerting the antagonift fibres, and producing a contraction in an oppofite direction, as is common in the exertions of our mufcles. Thus when we are tired with long action of our arms in one direction, as in holding a bridle on a journey, we occafion- ally throw them into an oppofite pofition to relieve the fatigued mufcles. Mr. Locke has defined an idea to be " whatever is prefent to the mind ;" but this would include the exertions of volition, and the fenfations of pleafure and pain, as well as thofe operations of our fyftem, which acquaint us with external objects ; and is therefore too unlimited for our purpofe. Mr. Locke feems to have fallen into a further error, by con- ceiving, that the mind could form a general or ab- ftract idea by its own operation, which was the copy of no particular perception ; as of a triangle in general, that was neither acute, obtufe, nor right angled. The ingenious Dr. Berkley and Mr. Hume have demonftrated, that fuch general ideas have no exigence in nature, not even in the mind of their celebrated inventor. We ihall therefore take for granted at prefent, that our recollection or imagination of external objects confifts of a partial repetition of the perceptions, which were excited by thofe external objects, at the time we became ac- quainted with them ; and that our reflex ideas of the operations of our minds are partial repetitions of thofe operations. II, The following article evinces that the organ of vifion confifts of a fibrous part as well as of the nervous medulla, like other white mufcles ; and hence, as it refembles the mufcular parts of the body SECT. III. 3. MOTIONS OF THE RETINA. 19 body in its ftruclure, we may conclude, that it muft refemble them in poflefling a power of being excit- ed into animal motion. — -The fubfequt-nt experi- ments on the optic nerve, and on the colours re- maining in the eye, are copied from a paper on ocu- lar fpecira publifhed in the feventy-fixth volume of the Philof. Tranf. by Dr. R. Darwin of Shrewf- bury ; which, as I mail have frequent occafion to refer to, is reprinted in this work, Seel:. XL. The retina of an ox's eye was fufpended in a glafs of warm water, and forcibly torn in a few places ; the edges of thefe parts appeared jagged and hairy, and did not contract and become fmooth like (imple mucus, when it is diftended till it breaks ; which evinced that it confifled of fibres. This fibrous conftruction became ftill more diftincl to the fight by adding fome cauftic alcali to the water ; as the adhering mucus was firft eroded, and the hair-like fibres remained floating in the veffeL Nor does the degree of tranfparency of the retina invalidate this evidence of its fibrous ftrudure, fince Leeuwenhoek has fliewn, that the cryftaJline humour itfelf confilb of fibres. Arc. Nat. V. I. 70. Hence it appears, that as the mufcles confift of larger fibres intermixed with a fmaller quantity of nervous medulla, the organ, of vifion confift-s of a greater quantity of nervous medulla intermixed with fmaller fibres. It is probable that the locomo- tive mufcles c/f microfcopic animals may have greater tenuity than thofe of the retina ; and there is reafon to conclude from analogy, that the other immediate organs of fenfe, as the portio molHs of the-auditory nerve, and. the rete mucofum of the ikin, poffefs a fimilarity of ftruclure with the reti- na, and a fimilar power of being excited into anU mal motion. III. The fubfequent articles {hew, that neither mechanical impreffions, nor chemical combinations. of ?o MOTIONS OF THE RETINA. SECT. HI, 5. of light, but that the animal adivity of the retina conftitutes vifion. i. Much has been conjectured by philosophers about the momentum of the rays of light ; to fubjecl: this to experiment a very light horizontal balance was conftrucled by Mr. Michel, with about an inch fquare of thin leaf-copper fufpended at each end of it, as defcribed in Dr. Prieftley's Hiftory of Light and Colours. The focus of a very large convex mirror was thrown by Dr. Powel, in his lectures on experimental phiiofophy, in my prefence, on one wing of this delicate balance, and it receded from the light ; thrown on the other wing, it approached towards the light, and this repeatedly ; fo that no fenlible impulie could be obferved, but what might well be afcribed to the afcent of heated air. Whence it is reafonable to conclude, that the light of the day muft be much too weak in its dilute ftate to make any mechanical impreflion on fo tena- cious a fubftance as the retina of the eye. — -Add to this, that as the retina is nearly tranfparent, it could therefore make lefs refinance to the mechanical im- pulfe of light;- which, according to the obfervati- ons related by Mr. Melvil in the Edinburgh Literar ry Effays, only communicates heat, and fhould there- fore only communicate momentum, where it is ob- ftrucled, reflected, or refracted. — -From whence alfo niay be collected the final caufe of this degree of tranfparency of the retina, viz. left by the focus of flronger lights, heat and pain mould have been pro- duced in the retina, inftead of that ftimulus which excites it into animal motion. 2. On looking long on an area of fcarlet filk of about an inch in diameter laid on white paper, as in Plate I. the fcarlet colour becomes fainter, till at length it entirely vanifhes, though the eye is kept uniformly and tieadily upon it. Now if the change $f motipn of the retina was a mechanical imprcffi. SECT. III. 3. MOTIONS OF THE RETINA. , 21 on, or a chemical tinge of coloured light, the per- ception would every minute become ftronger and ftronger — whereas in this experiment it becomes every inftant weaker and weaker. The fame cir- cumflance obtains in the continued application of found, or of fapid bodies, or of odorous ones, or of tangible oness to their adapted organs of icnfe. Thus when a circular coin, as a {hilling, is preffed on the palm of the hand, the fenfe of touch is me- chanically compreffed ; but it is the flimulus of this preflure that excites the organ of touch into ani- mal action, which conftitutes the perception of hardnefs and of figure : for in feme minutes the perception ceafes, though the mechanical prefTure of the object remains. 3. Make with ink on white paper a very black fpot about half an inch in diameter, with a tail about an inch in length, fo as to refemble a tadpole, as in Plate II. ; look ftedfaftly for a minute on the center of this fpot, and on moving the eye a little, the figure of the tadpole \vill be feen on the white part of the paper j which figure of the tadpole will ap- pear more luminous than the other part of the white paper ; which can only be explained by fuppofing a part of the retina, on which the tadpole was delineated, to have become more fenfible to light than the other parts of it, which were expofed to the white paper ; and not from any idea of mecha- nical impreffion or chemical combination of light with the retina. 4. When any one turns round rapidly, till he be- comes dizzy, and falls upon the ground, the fpec- tra of the ambient objects continue to prefent them- felves in rotation, and he feems to behold the ob- jects ftillin motion. Now if thefe fpectra were im- preflions on a paffive organ, they either muft conti- nue as they were received laft, or not continue at ill, 5- Placq 22 MOTIONS OF THE RETINA. SECT. III. 3. 5. Place a piece of red filk about an inch in dia- meter on a fheet of white paper in a ftrong light, as in Plate I. ; look fteadily upon it from the diftance of about half a yard for a minute ; then doling your eye-lids, cover them with your hands and hand- kerchief, and a green fpeclrum will be feen in your eyes refembling in form the piece of red filk. After fome feconds of time the fpeftrum will difappear, and in a few more feconds will reappear ; and thus alternately three or four times, if the experiment be well made, till at length it vanifhes entirely. 6. Place a circular piece of white paper, about four inches in diameter, in the funfhine, cover the center of this with a circular piece of black filk, about three inches in diameter ; and the center of the black filk with a circle of pink filk, about two inches in diameter ; and the center of the pink filk with a circle of yellow filk, about one inch in dia- meter ; and the center of this with a circle of blue fiik, about half an inch in diameter ; make a fmall fpot with ink in the center of the blue filk, as in Piate 111. look fteadily for a minute on this central fpot, and then clofing your eyes, and applying your hand at about an inch diftance before them, fo as to prevent too much or too little light from paffing through the eye-lids, and you will fee the moft beau- tiful circles of colours that imagination can con* ceive ; which are moft refembled by the colours oc- cafioned by pouring a drop or two of oil on a ftili lake in a bright day. But thefe circular irifes of co- lours are not only different from the colours of the filks above mentioned, but are at the fame time per* petually changing as long as they exift* From all thefe experiments it appears, that thefe fpectra in the eye are not owing to the mechanical impulfe of light impreffed on the retina ; nor to its chemical combination with that organ ; nor to the abforption and emiffion of light j as is fuppofed perhaps SECT. 111.4. MOTIONS OF THE RETINA. 2* perhaps crroncoufly, to take place in calcined fhells and other phofphorefcent bodies, after having been expofed to the light : for in all thefe cafes the fpec- tra in the eye ftiould either remain of the fame co- lour, or gradually decay, when the object is with- drawn ; and neither their evanefcence during the prefence of their object, as in the fecond experi- ment, nor their change from dark to luminous, as in the third experiment, nor their rotation, as in the fourth experiment, nor the alternate prefence and evanefcence of them, as in the fifth experiment, nor the perpetual change of colours of them, as in the laft experiment, could exift. IV. The fubfequent articles ihew, that thefe ani- mal motions or configurations of our organs of fenfe conftitute our ideas. 1. If any one in the dark prefles the ball of his eye, by applying his finger to the external corner of it, a luminous appearance is obferved ; and by a fmart ftroke on the eye great flafhes of fire are perceived. (Newton's Optics.) So that when the arteries, that are near the auditory nerve, make flronger pulfations than ufual, as in fome fevers, an undulating found is excited in the ears Hence it is not the prefence of the light and found, but the motions of the organ, that are immediately ne- ceflary to conftitute the perception or idea of light and found. 2. During the time of fleep, or in delirium, the ideas of imagination are midaken for the percepti- ons of external objects ; whence it appears, that thefe ideas of imagination are no other than a rei- teration of thofe motions of the organs of fenfe, which were originally excited by the ftimulus of external objects : and in our waking hours the fim- ple ideas, that we call up by recollection or by imagination, as the colour of red, or the fmell of a rofe, 24 MOTH3NS OF THE RETINA. S*CT. III. 4. a rofe, are exact refemblanccs of the fame fimplc ideas from perception ; and in confequence muft be a repetition of thofe very motions. 3. The difagreeable fenfation called the tooth- edge is originally excited by the painful jarring of the teeth in biting the edge of the glafs, or porce- lain cup, in which our food was given us in our in- fancy, as is further explained in the Section XVI. 10, on Inftinft. — This di {agreeable fenfation is after- wards excitable not only by a repetition of the found, that was then produced, but by imaginati- on alone, as I have myfelf frequently experienced ; in this cafe the idea of biting a china cup, when I imagine it very diftinclly, or when I fee another perfon bite a cup or glafs, excites an actual pain in the nerves of my teeth. So that this idea and pain ieem to be nothing more than the reiterated motions of thofe nerves, that were formerly fo difagreeably affected. Other ideas that are excited by imagination or ' recollection in many inftances produce flmilar ef- fects on the conftitution, as our perceptions had formerly produced, and are therefore undoubtedly a repetition of the fame motions. A ftory which the celebrated Baron Van Swieten relates of him- felf is to this purpose. He was prefent when the putrid carcafe of a dead dog exploded with prodi- gious ftench ; and fome years afterwards, acciden- tally riding along the fame road, he was thrown into the fame ficknefs and vomiting by the idea of the ftench, as he had before experienced from the perception of it. 4. Where the organ of fenfeis totally deftroyed, the ideas which were received by that organ feem to peri Hi along with it, as well as the power of per- ception. Of this a fatisfactory inftance has fallen under my obfervation. A gentleman about fixty years of age had been totally deaf for near thirty years : SECT. III. 5. MOTIONS OF THE RETINA, 25 years : he appeared to be a man of good under- ftanding, and amufed himfelf with reading, and by converfine: either by the ufe of the pen, or by figns made with his fingers, to reprefent letters. I ob- ferved that he had' ib far forgot the pronunciation of the language, that when he attempted to fpeak, none of his words had diftinct articulation, though his relations could fometimes underftand his mean- ing. But, which is much to the point, he allured me, that in his dreams he always imagined that people converfed with him by figns or writing, and never that he heard any one fpeak to him. From hence it appears, that with the perceptions of founds he has alfo loft the idea of them ; though the or- gans of fpeech dill retain fomewhat of their ufual habits of articulation. This obfervation may throw fome light on the medical treatment of deaf people ; as it may be learnt from their dreams, whether the auditory nerve be paralytic, or their deafnefs be owing to fome defect of the external organ. It. rarely happens that the immediate organ of vifion is perfectly deftroyed. The moft frequent caufes of blindnefs are occaiioned by defects of the external organ, as in cataracts and obfufcations of the cornea. But 1 have had the opportunity of converfing with two men, who had been fome years blind; one of them had a complete gutta ferena, and the other had loft the whole fubftance of his eyes. They both told me that they did not re- member to have ever dreamt of vifible objects, fmce the total lofs of their fight. V. Another method of difcovering that our ideas are animal motions of the organs of fenfe, is from confidering the great analogy they bear to the mo- tions of the larger mufcles of the body. In the following articles it will appear that they are ori- ginally excited into action by the irritation of ex- ternal 26 MOTIONS OF THE RETINA. SECT, III. j. ternal objects like our mufcles ; are affociated toge- ther like our mufcular motions ; act in limilar time with them ; are fatigued by continual exertion like them; and that the organs of fenfe are fubject to inflammation, numbnefs, palfy, convulfion, and the defects of old age, in the fame manner as the mufcular fibres. 1. All our perceptions or ideas of external ob- jects are univerfally allowed to have been originally excited by the ftimulus of thofe external objects ; and it will be (hewn in a fucceeding fectlon, that it is probable that all our mufcular motions, as well thofe that are ^become voluntary as thofe of the heart and glandular fyftem, were originally in like manner excited by the ftimulus of fomething exter- nal to the organ of motion. 2. Our ideas are alfo affociated together after their production precifely in the fame manner as our mufcular motions ; which will likewifebe fully ex- plained in the fucceeding fection. 3. The time taken up in performing an idea is like wife much the fame as that taken up in perform- ing a mufcular motion. A mufician can prefs the - keys of an harpfichord with his fingers in the or- der of a tune he has been accuftomed to play, in as little time as he can run over thofe notes in his mind. So we many times in an hour cover our eye- balls with our eye- lids without perceiving that we are in the dark ; hence the perception or idea of light is not changed for that of darknefs in fo fmali a time as the twinkling of an eye; fo that in this cafe the mufcular motion of the eye-lid is perform- ed quicker' than the perception of light can be changed for that of darknefs. — So if a fire-ftick be \vlnrfed round. in the dark, a luminous circle ap- pears to the obferver ; if it be whirled fomewhaC flower, this circle becomes interrupted in one part ; and then the time taken up in fuch a revolution of the ICT. III. 5. MOTIONS OF THE RETINA. 27 the flick is the fame that the obferver ufes in chang- ing his ideas : thus the ^x,ootMW aw of Homer, the long (hadow of the flying javelin, is elegantly de- figned to give us an idea of its velocity, and not of its length. 4. The fatigue that follows a continued attention of the mind to one object is relieved by changing the fubjeft of our thoughts ; as the continued movement of one limb is relieved by moving an- other in its (lead. Whereas a due exercife of the fa- culties of the mind ftrengthens and improves thofe faculties, whether of imagination or recolle&ion ; as the exercife of our limbs in dancing or fencing increafes the ftrength and agility of the mufcles thus employed. 5. If the mufcles of any limb are inflamed, they do not move without pain ; fo when the retina is inflamed, its motions alfo are painful. Hence light is as intolerable in this kind of ophthalmia, as pref- fure is to the finger in the paronychia. In this dif- eafe the patients frequently dream of having their eyes painfully dazzled; hence the idea of ftrong light is painful as well as the reality, The firft of thefe facts evinces that our perceptions are motions of the organs of fenfe; and the latter, that our imaginations are alfo motions of the fame organs. 6. The organs of fenfe, like the moving mufcles, are liable to become benumbed, or lei's fenfible, from comprefllon. Thus, if any perfon on a light day looks on a white wall, he may perceive the ra- mifications of the optic artery, at every pulfation of it, reprefented by darker branches on the white wall ; which is evidently owing to its comprefling the retinue during the diaftole of the artery. Sa- vage Noiblog. 7. The organs of fenfe and the moving mufcles are alike liable to be affe&ed with palfy, as in the D gutta 2S MOTIONS OF THE RETINA. SECT. III. 5. gutta ferena, and in fome cafes of deafnefs ; and one fide of the face has fometimes loft its power of fenfation, but retained its power of motion ; other parts of the body have loft their motions but re- tained their fenfation, as in the common hemipla- gia ; and in other inftances both thefe powers have perifhed together. 8. In fome convulfive difeafes a delirium or infa- nity fupervenes, and the convulfions ceafe ; and converfely the convulfions fhall fupervene, and the delirium ceafe. Of this I have been a witnefs ma- ny times in a day in the paroxyfms of violent epi- lepfies ; which evinces that one kind of delirium is a convulfion of the organs of fenfe, and that our ideas are the motions of thefe organs : the fubfe- quent cafes will illuftrate this obfervation. Mifs G , a fair young lady, with light eyes and hair, was feized with moft violent convul- fions of her limbs, with outrageous hiccough, and moft vehement efforts to vomit : after near an hour xvas elapfed this tragedy ceafed, and a calm talkative delirium fupervened for about another hour ; and thefe relieved each other at intervals during the greateft part of three or four days. After having carefully confidered this difeafe, I thought the con- vulfions of her ideas lefs dangerous than thofe of her mufcles ; and having in vain attempted to make any opiate continue in her ftomach, an ounce of laudanum was rubbed along the fpine of her back, and a dram of it was uled as an enema ; by this me- dicine a kind of drunken delirium was continued rnany hours ; and when it ceafed the convulfions did not return ; and the lady continued well many years, except fome {lighter relapfes, which were re- lieved in the fame manner. Mifs H , an accomplifhed young lady, with light eyes and hair, was feized with convulfions of her iiaibs, with hiccough, and efforts to vomit, more SECT. III. 5, MOTIONS OF THE RETINA. 29 more violent than words can exprefs ; thefe conti- nued near an hour, and were fucceeded with a ca- taleptic fpafm of one arm, with the hand applied to her head ; and after about twenty minutes thefe fpafms ceafed, and a talkative reverie fupervened for near another hour, from which no violence, which it was proper to ufe, could awaken her. Thefe periods of convulfions, firft of the mufcles, and then of the ideas, returned twice a day for fe- veral weeks; and were at length removed by great dofes of opium, after a great variety of other me- dicines and applications had been in vain experi- enced. This lady was fubject to frequent relapfes, once or twice a year for many years, and was as frequently relieved by the fame method. Mifs W , an elegant young lady, with black eyes and hair, had fometimes a violent pain of her fide, at other times a moft painful ftrangury, which were every day fucceeded by delirium ; which gave a temporary relief to the painful fpafms. After the vain exhibition of variety of medicines and applications by different phyficians, for more than a twelvemonth, me was directed to take fome dofes of opium, which were gradually increafed, by which a drunken delirium was kept up for a day or two, and the pains prevented from returning. A flefh diet, with a little wine or beer, inftead of the low regimen fhe had previoufly ufed, in a few weeks completely eftabliflied her health ; which, except a few relapfes, has continued for many years. 9. Laflly, as we advance in life all the parts of the body become more rigid, and are rendered lefs fufceptible of new habits of motion, though they retain thofe that were before eftablifhed. This is fenfibly obferved by thofe who apply themfelves late in life to mufic, fencing, or any of the mecha- nic arts. In the fame manner many elderly peo- D 2 pic 30 MOTIONS OF THE RETINA. SECT. III. 6. pie retain the ideas they had learned early in life, but find great difficulty in acquiring new trains of memory ; infomuch that in extreme old age we frequently fee a forgetfulnefs of the bufinefs of yef- terday, and at the fame time a circumftantial re- membrance of the amufements of their youth ; till at length the ideas of recollection and activity of the body gradually ceafe together — fuch is the con- dition of humanity ! — and nothing remains but the vital motions and fenfations. VI. i. In oppofition to this doctrine of the pro- duction of our ideas, it may be afked, if fome of our ideas, like other animal motions, are volunta- ry, why can we not invent new ones, that have not been received by perception ? The anfwer will be better underftood after having perufed the fuc- ceeding lection, where it will be explained, that the mufcular motions likewife are originally excited by the ftimulus of bodies external to the moving organ ; and that the will has only the power of re- peating the motions thus excited. 2. Another objector may alk, Can the motion of an organ of fenfe referable an odour or a colour ? To which I can only anfwer, that it has not been dernonflrated that any of our ideas refemble the ob- jects that excite them : it has generally been be- lieved that they do not ; but this ftiall be difcuffed at large in Seel. XIV. 5. There is another objection that at firft view would feem lefs eafy to furmount. After the am- putation of a foot or a finger, it has frequently hap- pened, that an injury being offered to the (lump of the amputated limb, whether from cold air, too great preffure, or other accidents, the patient has complained of a fenfation of pain in the foot or finger, that was cut off. Does not this evince that all our ideas are excited in the brain, and not in the organs of fenfe ? This objection is anfwered, by SECT. III. 7. MOTIONS OF THE RETINA. 31 by obferving that our ideas of the (hape, place, and folidity of our limbs, are acquired by our organs of touch and of fight, which are fituated in our fingers and eyes, and not by any fenfations in the limb itfelf. In this cafe the pain or fenfation, which formerly has arifen in the foot or toes, and been propagated along the nerves to the central part of the fenfo- rium, was at the fame time accompanied with a vifible idea of the fhape and place, and with a tan- gible idea of the folidity of the affected limb : now when thefe nerves are afterwards affected by any injury done to the remaining flump with a fimilar degree or kind of pain, the ideas of the fhape, place, or folidity of the loft limb, return by affo- ciation ; as thefe ideas belong to the organs of fight and touch, on which they were firfl excited. 4. If you wonder what organs of fenfe can be excited into motion, when you call up the ideas of wifdom or benevolence, which Mr. Locke has termed abftracled ideas ; I alk you by what organs of fenfe you firft became acquainted with thefe ideas ? And the anfwer will be reciprocal ; for it is certain that all our ideas were originally acquired by our organs of fenfe ; for whatever excites our perception muft be external to the organ that per- ceives it, and we have no other inlets to knowledge but by our perceptions : as will be further explain- ed in Section XIV. and XV. on the Productions and Clafles of Ideas. VII. If our recollection or imagination be not a repetition of animal movements, I afk, in my turn, What is it ? You tell me it confifts of images or pictures of things. Where is this extenfive canvas hung up ? or where are the numerous receptacles in which thofe are depofited ? or to what elfe in the animal fyftem have they any fimilitude ? That ANIMAL CAUSATION. SECT. IV. i. ^ pleafing picture of objects, reprefented in miniature on the retina of the eye, feems to have given rife to this illufive oratory ! It was forgot that this reprefentation belongs rather to the laws of light, than to thofe of life ; and may with equal ele- gance be feen in the camera obfcura as in the eye ; and that the picture vaniflies for ever, when the object is withdrawn. SECT. IV. LAWS OF ANIMAL CAUSATION. I. The fibres, which conftitute the mufcles and organs of fenfe, poflefs a power of contraction. The circumftances attending the exertion of this power of CONTRACTION constitute the laws of ani- mal motion, as the circumftances attending the ex- ertion of the power of ATTRACTION conftitute the laws of motion of inanimate matter. II. The fpirit of imagination is the immediate caufe of the contraction of animal fibres, it refides in the brain and nerves, and is liable to general or partial diminution or accumulation. III. The ftimulus of bodies external to the mov- ing organ is the remote caufe of the original con- tractions of animal fibres. IV. A certain quantity of ftimulus produces ir- ritation, which is an exertion of the fpirit of ani- mation exciting the fibres into contraction. V. A certain quantity of contraction of animal fibres, if it be perceived at all, produces pleafure ; a great- Seer IV. 7. ANIMAL CAUSATION. 33 a greater or lefs quantity of contraction, if it be perceived at all, produces pain ; thefe conftitute fenfation. VI. A certain quantity of fenfation produces de- lire or averfion ; thefe conftitute volition. VII. All animal motions which have occurred at the fame time, or in immediate fucceffion, become fo connected, that when one of them is reproduced, the other has a tendency to accompany or fucceed it. When fibrous contractions fucceed or accompany other fibrous contractions, the connection is termed affociation ; when fibrous contractions fucceed fen- forial motions, the connection is termed caufation ; when fibrous and fenforial motions reciprocally in- troduce each other, it is termed catenation of ani- mal motions. All thefe connections arefaid to be pro- duced by habit, that is, by frequent repetition. Thefe laws of animal caufation will be evinced by numerous facts, which occur in our daily exertions; and will afterwards be employed to explain the more recon- dite phaenomena of the production, growth, dif- cafes, and decay of the animal fyftem. SECT, 34 SENSORIAL FACULTIES. Sicr.V. SECT. V. OF THE FOUR FACULTIES OR MOTIONS OF THE SEN- SORIUM. I. Four fenforial powers. 2. Irritation, fenfatlon^ vo- lition, ajjoclation defined. 3. Senforial motions dif- tlnguijhed from fibrous motions. 1. THE fpirit of animation has four different modes of action, or in other words the animal fen- forium poffeffes four different faculties, which are occaiionally exerted, and caufe all the contractions of the fibrous parts of the body, Thefe are the faculty of caufing fibrous contractions in confe- quence of the irritations excited by external bodies, in confequence of the fenfationsof pleafure or pain, in confequence of volition, and in confequence of the affociations of fibrous contractions with other fibrous contractions, which precede or accompany them. Thefe four faculties of the fenforium during their inactive (late are termed irritability, fenfibility, vo- luntarity, and affectability ; in their active flate they are termed as above, irritation, fenfation, vo- lition, afibciation. 2. IRRITATION is an exertion or change of fome extreme part of the fenforium reading in the muf- cles or organs of fenfe, in confequence of the ap- pulfes of external bodies. SENSATION is a,n exertion or change of the cen- tral parts of the fenforium, or of the whole of it, beginning at fome of thofe extreme parts of it, which refide in the mufcles or organs of fenfe. VOLITION SECT.V. SENSORIAL FACULTIES. 35 VOLITION is an exertion or change of the central parts of the fenforium, or the whole of ^it, termi- nating in fome of thofe extreme parts of it, which refide in the mufcles or organs of fenfe. ASSOCIATION is an exertion or change of fome extreme part of the fenforium refiding in the muf- cles or organs of fenfe, in confequence of fome an- tecedent or attendant fibrous contractions. 3. Thefe four faculties of the animal fenforium may at the time of their exertions be termed mo- tions without impropriety of language ; for we cannot pafs from a ftate of infenfibility or inaction to a ftate of fenfibility or of exertion without fome change of the fenforium, and every change includes motion. We fhall therefore fometimes term the above defcribed faculties fenforial motions to diftin- guifli them from fibrous motions ; which latter ex- preffion includes the motions of the mufcles and or- gans of fenfe. The adive motions of the fibres, whether thofe of the mufcles or organs of fenfe, are probably fimple contractions ; the fibres being again elongat- ed by antagonifl mufcles, by circulating fluids, or fometimes by elaftic ligaments, as in the necks of quadrupeds. The feniorial motions, which confti- tute the fenfations of pleafure or pain, and which conftitute the fenfations of pleafure or pain, and which conftitute volition, and which caufe the fi- brous contractions in confequence of irritation or of aflbciation, are not here fuppofed to be fluctua- tions or refluctuations of the fpirit of animation ; nor are they fuppofed to be vibrations or revibrati- ons, nor condenfations or equilibrations of it; but to be changes or motions of it peculiar to life. SECT. 36 FIBROUS CONTRACTIONS. SECT. VI. i, •Js-mm ii^j "i \i> Taaofmxa a* srvfo, . SECT. VL OF THE FOUR CLASSES OF FIBROUS MOTIONS. i* *JS ' i I. Origin of fibrous contractions. II. Diftribution of them into four c/qffes, irritative motions y fenfit'we mo* tions, 'voluntary motions, and officiate motions, defined. I. ALL the fibrous contractions of animal bodies originate from the fenforium, and refolve them- felves into four clafles, correfpondent with the four powers or motions of the fenforium above defcrib- ed, and from which they have their caufation. 1. Thefe fibrous contractions were originally caufed by the irritations excited by objects, which are external to the moving organ. As the pulfati- ons of the heart are owing to the irritations excited by the ftimulus of the blood ; and the ideas of per- ception are owing to the irritations excited by ex- ternal bodies. 2. But as painful or pleafurable fenfations fre- quently accompanied thofe irritations, by habit thefe fibrous contractions became caufable by the fenfa- tions, and the irritations ceafed to be neceflary to their production. As the fecretion of tears in grief is caufed by the fenfation of pain ; and the ideas of imagination, as in dreams or delirium, are excited by the pleafure or pain, with which they were for- merly accompanied. 3. But as the efforts of the will frequently ac- companied thefe painful or pleafurable fenfations, by habit the fibrous contractions became caufable by volition ; and both the irritations and fenfations ceafed to be neceflary to their production. As the deliberate SECT. VI. 2. FIBROUS CONTRACTIONS. 37 deliberate locomotions of the body, and the ideas of recolleftion, as when we will to repeat the alpha- bet backwards. 4. But as many of thefe fibrous contractions fre- quently accompanied other fibrous contractions, by habit they became caufable by their affociations with them; and the irritations, fenfations, and vo- lition, ceafed to be neceffary to their production. As the actions of the mufcles of the lower limbs in fencing are affociated with thofe of the arms ; and the ideas of fuggeftion are affociated with other ideas, which precede or accompany them ; as in re- peating carelefsly the alphabet in its ufual order af- ter having began it. II. We fhall give the following names to thefe four claffes of fibrous motions, and fubjoin their definitions. 1. Irritative motions. That exertion or change of the fenforium, which is caufed by the appulfes of external bodies, either fimpiy fubfides, or is fuc- ceeded by fenfation, or it produces fibrous motions ; it is termed irritation, and irritative motions are thofe contractions of the mufcular fibres, or of the organs of fenfe, that are immediately confequent to this exertion or change of the fenforium. 2. Senfitive motions. That exertion or change of the fenforium, which conftitutes pleafure or pain, either fimpiy fubfides, or is fucceeded by vo- lition, or it produces fibrous motions ; it is termed fenfation, and the fenfitive motions are thofe con- tractions of the mufcular fibres, or of the organs of fenfe, that are immediately confequent to this exertion or change of the fenforium. 3. Voluntary motions. That exertion or change of the fenforium, which conftitutes defire or aver- fion, either fimpiy fubfides, or is fucceeded by fibrous motions \ it is then termed volition, and vo- luntary 38 IRRITATIVE MOTIONS. SECT. VII. r. luntary motions are thofe contractions of the muf- cular fibres, or of the organs of fenfe, that are im- mediately confequent to this exertion or change of the fenforium. 4. Affociate motions. That exertion or change of the fenforium, which accompanies fibrous mo- tions, either limply fubfides, or is fucceeded by fenfation or volition, or it produces other fibrous motions ; it is then termed affociation, and the affociate motions are thofe contractions of the muf- cular fibres, or of the organs of fenfe, that are im- mediately confequent to this exertion or change of the fenforium. SECT. VII. OF IRRITATIVE MOTIONS. I. i. Some mufeular motions are excited by perpetual irritations, i. Others more frequently by fenfations. 3. Others by volition. Cafe of involuntary ft retch- ings in paralytic limbs. 4. Some fenfual motions are excited by perpetual irritations. 5. Others more fre- quently by fenfation or volition. II. i. Mufeular motions excited by perpetual irrita- tions occajionally become obedient to fenfation and to volition. 2. And the fenfual motions. III. i. Other mufeular motions are ajfociated with the irritative ones. 2. And other ideas with irritative ones. Of letters, language, hieroglyphics. Irrita- tive ideas exift without our attention to them. vrf " -jb; V> ,Vj.".-..^.-^--.--vfe.:r'.fii- Tj$fb •,*«'*£ I. i. MANY of our mufeular motions are ex- cited by perpetual irritations, as thofe of the heart and SECT. VII. i. IRRITATIVE MOTIONS. 39 and arterial fyftem by the circumfluent blood- Many other of them are excited by intermitted ir- ritations, as thofe of the ftomach and bowels by the aliment we fwallow ; of the bile-ducts by the bile ; of the kidneys, pancreas, and many other glands, by the peculiar fluids they feparate from the blood ; and thofe of the lacteal and other fubfequent veflels by the chyle, lymph, and moifture of the atmofphere. Thefe motions are accelerated or retarded, as their correfpondent irritations are increafed or diminifhed, without our attention or confcioufnefs, in the fame manner as the various fecretions of fruit, gum, re- fin, wax, and honey, are produced in the vegeta- ble world, and as the juices of the earth and the mpifture of the atmofphere are abforbed by their roots and foliage. 2. Other mufcular motions, that are moft fre- quently connected with our fenfations, are thofe of the fphincters of the bladder and anus, and the muf- culi erectores penis, were originally excited into motion by irritation, for young children make wa- ter, and have other evacuations without attention to thefe circumftances ; " et primis etiam ab incu- nabulis tenduntur faepius puerorum penes, amore nondum expergefacto." So the nipples of young women are liable to become turgid by irritation, long before they are in a fituation to be excited by the pleafure of giving milk to the lips of a child. 3. The contractions of the larger mufcles of our bodies, that are mod frequently connected with volition, were originally excited into action by in- ternal irritations : as appears from the ftretching or yawning of all animals after long fleep. In the be- ginning of fome fevers this irritation of the mufcles produces .perpetual ftretching and yawning ; in other periods of fever an univerfal reftleflhefs arifes from the fame caufe, the patient changing the at- titude of his body every minute. The repeated ftruggles 40 IRRITATIVE MOTIONS, SECT. VII. I. ftruggles of the foetus in the uterus muft be owing to this internal irritation : for the foetus can have no other inducement to move its limbs but the tse- dium or irkfomenefs of a continued pofture. The following cafe evinces, that the motions of ftretching the limbs after a continued attitude are not always owing to the power of the will. Mr. Dean, a mafon, of Auftry in Leicefterfliire, had the fpine of the third vertebra of the back enlarg- ed ; in fome weeks his lower extremities became feeble, and at length quite paralytic : neither the pain of blifters, the heat of fomentations, nor the utmoft efforts of the will could produce the lead motion in thefe limbs ; yet twice or thrice a day for many months his feet, legs, and thighs, were affected for many minutes with forcible ftretch- Ings, attended with the fenfation of fatigue ; and he at length recovered the ufe of his limbs, though the fpine continued protuberant. The fame cir- cum fiance is frequently feen in a lefs degree in the common hemiplagia ; and when this happens, I have believed repeated and flrong mocks of electri- city to have been of great advantage. 4. In like manner the various organs of fenfe are originally excited into motion by various external ftimuli adapted to this purpofe, which motions are termed perceptions or ideas ; and many of thefe motions during our waking hours are excited by perpetual irritation, as thofe of the organs of hear- ing and of touch. The former by the conftant low indiftinct noifes that murmur around us, and the latter by the weight of our bodies on the parts which fupport them ; and by the unceafing varia- tions of the heat, moifture, and preflure of the at- mofphere ; and thefe fenfual motions, precifely as the mufcular ones above mentioned, obey their cor- refpondent irritations without our attention or con- fcioumefs. 5. Other SECT. VII. 2. IRRITATIVE MOTIONS. 41 5. Other clafies of our ideas are more frequent- ly excited by our fenfations of pleafure or pain, and others by volition : but that thefe have all been originally excited by ftimuli from external objects, and only vary in their combinations or reparations, has been fully evinced by Mr. Locke : and are by him termed the ideas of perception in contradiilinc- tion to thofe, which he calls the ideas of reflec- tion. II. i. Thefe mufcular motions, that are excited by perpetual irritation, are neverthelefs occafion- ally excitable by the fenfations of pleafure or pain, or by volition ; as appears by the palpitation of the heart from fear, the increafed fecretion of faliva at the fight of agreeable food, and the glow on the Ikin of thofe who are amamed. I here is an inftance told in the Philofophical Tr an factions of a man, who could for a time flop the motion of his heart when he pleafed ; and Mr. D. has often told me, he could Ib far increafe the periftaltic motion of his bowels by voluntary efforts, as to produce an evacuation by ftool at any time in half an hour. 2. In like manner the fenfual motions, or ideas, that are excited by perpetual irritation, are never- thelefs occafionally excited by fenfation or volition ; as in the night, when we liften under the influence of fear, or from voluntary attention, the motions excited in the organ of hearing by the whifpering of the air in our room, the pulfation of our own ar- teries, or the faint beating of a diltant watch, be- come objects of perception. ill. Innumerable trains or tribes of other motions are aflbciated with thefe mufcular motions which are excited by irritation ; as by the ftimulus of the blood in the right chamber of the heart, the lungs are induced to expand themfelves ; and the pecto- ral and intercoftal mufcles, and the diaphragm, act at the fame time by their aiTociations with them. And 4* IRRITATIVE MOTIONS. SECT. VII. 3. And when the pharynx is irritated by agreeable food, the mufcles of deglutition are brought into action by aflbciation. Thus when a greater light falls on the eye, the iris is brought into action with- out our attention ; and the ciliary procefs, when the focus is formed before or behind the retina, by their aflbciations with the increafed irritative mo- tions of the organ of vifion. Many common ac- tions of life are produced in a fimilar manner. If a fly fettle on my forehead, whilft I am intent on my prefent occupation, I diflodge it with my finger, without exciting my attention or breaking the train of my ideas. 2. In like manner the irritative ideas fuggeft to us many other trains or tribes of ideas that are af- fociated with them. On this kind of connection, language, letters, hieroglyphics, and every kind of fymbol, depend. The iymbols themfelves produce irritative ideas, or fenfual motions, which we do not attend to ; and other ideas, that are fucceeded by fenfation, are excited by their aflbciation with them. And as thefe irritative ideas make up apart of the chain of our waking thoughts, introducing other ideas that engage our attention, though them- felves are unattended to, we find it very difficult to inveftigate by what fteps many of our hourly trains of ideas gain their admittance. It may appear paradoxical, that ideas can exift, and not be attended to ; but all our perceptions are ideas excited by irritation, and fucceeded by fenfa- tion. Now when thefe ideas excited by irritation give us neither pleafure nor pain, weceafe to attend to them. Thus whilft 1 am walking through that grove before my window, I do not run againft the trees or the benches,^ though my thoughts are ftre- nuoufly exerted on fome other object. This leads us to a diftinct knowledge of irritative ideas, for the idea of the tree or bench, which I avoid, exifts on my SECT. VIII. i. SENSITIVE MOTIONS. 4$ my retina, and induces by affociation the aftion of certain locomotive mufcles ; though neither itfelf nor the actions of thole mufcles engage my atten* tion. Thus whilft we are converting on this fubjeclr, the tone, note, and articulation of every indivi- dual word forms its correfpondent irritative idea on the organ of hearing ; but we only attend to the aflfociated ideas, that are attached by habit to thefe irritative ones, and are fucceeded by fenfation ; thus when we read the words " PRINTING-PRESS" we do not attend to the fiiape, fize, or exiftence of the let- ters which compofe thefe words, though each of them excites a correfpondent irritative motion of our organ of viiion, but they introduce by affocia- tion our idea of the moil ufeful of modern inven- tions ; the capacious refervoir of human knowledge, whofe branching ftreams diffufe fciences, arcs, and morality, through all nations and all ages. SECT. VIJI. OF SENSITIVE MOTIONS. I. i. Senjltwe. .mufcular motions were originally excited Into aclion by irritation. 2. And fenfttive fenfual motions y ideas of 'imagination , dreams* II. i. 6V/z- Jttive mufcular motions are occasionally obedient to vo- lition. 2. And fenjitive fenfual motions. III. i. Other mufcular motions are officiated with the fenji- five ones. 2. And other fenfual motions. I. i. MANY of the motions of our mufcles, that are excited into action by irritation, are at K the H SENSITIVE MOTIONS. SECT. VIII. r the fame time accompanied with painful or pleafur- able fenfations ; and at length become by habit caufable by the fenfations. Thus the motions of the fphincters of the bladder and anus were origi- nally excited into action by irritation ; for young children give no attention to thefe evacuations ; but as foon as they become fenfible of the inconve- nience of obeying thefe irritations, they fuffer the water or excrement to accumulate, till it difagree- ably affects them ; and the action of thofe fphinc- ters is then in confequence of this difagreeable fen- fation. So the fecretion of faliva, which in young children is copioufly produced by irritation, and drops from their mouths, is frequently attended with the agreeable fenfation produced by the maf- tication of tafteful food ; till at length the fight of fuch food to a hungry perfon excites into action thefe falival glands j as is feen in the flavering of hungry dogs. The motions of thofe mufcles, which are affected by lafcivious ideas, and thofe which are exerted in fmiling, weeping, flatting from fear, and winking at the approach of danger to the eye, and at times the actions of every large inufcle of the body be- come caufable by our fenfations. And all thefe mo- tions are performed with ftrength and velocity in proportion to the energy of the fenfation that excites them, and the quantity of fenforialower. 2. Many of the motions of our organs of fenfe, or ideas, that were originally excited into action by irritation, become in like manner more frequently caufable by our fenfations of pleafure or pain. Theie motions are then termed the ideas of imagination, and makeup all the fcenery and tranfactions of our dreams. Thus when any painful or pleafurable fen- fations poflefs us, as of love, anger, fear ; whether in our fleep or waking hours, the ideas, that have been SECT. VIII. 3. SENSITIVE MOTIONS. 45 been formerly excited by the objefts of thefe fenfa- tions, now vividly recur before us by their connec- tion with thefe fenfations themfelves. So the fair fmiling virgin, that excited your love by her pre- fence, whenever that fenfation recurs, rifes before vou in imagination ; and that with all the pleafing circumftances, that had before engaged your atten- tion. And in fleep, when you dream under the in- fluence of fear, all the robbers, fires, and precipices, that you formerly have feen or heard of, arife be- fore you with terrible vivacity. All thefe fenfuai motions, like the mufcular ones above mentioned, are performed with ftrength and velocity in pro- portion to the energy of the fenfation of pleafure or pain, which excites them, and the quantity of fenforial power. III. i. Many of thefe mufcular motions above defcribed, that are mod frequently excited by our fenfations, are neverthelefs occafionally caufable by volition ; for we. can frnile or frown ipontaneoufly, can make water before the quantity or acrimony of the urine produces a difagreeable fenfation, and can voluntarily rnaflicate a naufeous drug, or fwallow a bitter draught, though our fenfation would ftrongly diffuade us. 2. In like manner the fenfuai motions, or ideas, that~are mod frequently excited by our fenfations, are neverthelefs occafionally caufeable by volition, as we can fponcaneoufly call up laft night's dream before us, tracing it induftrioufly ftep by ftep through all its variety of fcenery and t ran faction ; or can voluntarily examine or repeat the ideas, that have been excited by our difgutt or admiration. III. i. Innumerable trains or tribes of motions are affociated with thefe fenfitive mufcular motions above mentioned ; as when a drop of water failing into the wind-pipe difagreeably affects the air-veflcis of the lungs, they are excited into violent aclion ; E 2 and 46 VOLUNTARY MOTIONS. SECT, IX. i. and with thefe fenfitive motions are aflbciated the adtions of the pe&oral and intercoftal mufcles, and the diaphragm ; till by their united and repeated fucceilions the drop is returned through the larynx. The fame occurs when any thing difagreeably affects the noftrils, or the ftomach, or the uterus ; variety of mufcles "are excited by aflbciation into forcible action, not to be fuppreffed by the utmoft efforts of the will ; as in freezing/ vomiting, and parturi- tion. 2. In like manner with thefe fenfitive fenfual motions, or ideas of imagination, are affociated many other trains or tribes of ideas, which by fome writers of metaphyfics have been claffed under the terms of refemblance, caufation, and contiguity j and will be more fully treated of hereafter. SECT. IX. OF VOLUNTARY MOTIONS. I. i . Voluntary mufcular motions are originally excited by irritations. 2. And voluntary ideas. Of reajon. II. i. Voluntary mufcular motions are occasionally caufable by fenfations. 2. And voluntary ideas. 111. i. Voluntary mufcular motions are cccafionally obedient to Irritations. 2. And voluntary ideas. IV. i. Vo- luntary mufcular motions are affociated 'with other muf- cular motions. 2. And voluntary ideas. WHEN pleafure or pain affecl the animal fyftem, many of its motions both nuifcular and fenfual are brought SECT. IX. i. VOLUNTARY MOTIONS. 47 brought into aftion ; as was {hewn in the preceding fection, and were called fenfitive motions. The general tendency of thefe motions is to arreft and to poflefs the pleafure, or to diflodge or avoid the pain : but if this cannot immediately be accom- plifhed, defire or averfion are produced, and the motions in confequence of this new faculty of the fenforium are called voluntary. 1. i. Thofe mufcles of the body that are attach- ed to bones, have in general their principal conne- tions with volition, as 1 move my pen or raife my body. Thefe motions were originally excited by irritation, as was explained in the fection on that fubjecl, afterwards the fenfations of pleafure or pain, that accompanied the motions thus excited, induc- ed a repetition of them ; and at length many of them were voluntarily practifed in fucceiiion or in combination for the common purpofes of life, as in learning to walk, or to fpeak ; and are performed with ftrength and velocity in proportion to the energy of the volition, that excites them, and the quantity of fenforial power. 2. Another great clafs of voluntary motions con- fifts of the ideas of recollection. We will to repeat a certain train of ideas, as of the alphabet back- wards ; and if any ideas, that do not belong to this intended train, intrude themfelves by other con- nections, we will to reject them, and voluntarily perfifl in the determined train. So at my approach to a houfe which I have but once vilited, and that at the diftance of many months, I will to recollect the names of the numerous family I expect to fee there, and I do recollect them. On this voluntary recollection of ideas our facul- ty of reafon depends, as it enables us to acquire an idea of the diffimilitude of any two ideas. Thus if you voluntarily produce the idea of a right-angled triangle, and then of a fquare ; and after having excited 48 VOLUNTARY MOTIONS. SECT. IX. 3. excited thefe ideas repeatedly, you excite the idea of their difference, which is that of another right- angled triangle inverted over the former ; you are faid to reafon upon this- fubject, or to compare your ideas. Thefe ideas of recollection, like the mufcular mo- tions above1 mentioned, were originally excited by the irritation of external bodies, and were termed ideas of perception: afterwards the pleafure or pain, that accompanied thefe motions, induced a repetition of them in the abfence of the external body, by which they were fir ft excited ; and then they were termed ideas of imagination. At length they become voluntarily practifed in fuccceflion or in combination for the common purpofes of life;" as when we make ourfelves matters of the hiftory of mankind, or of the fciences they have inveftigat- cd ; and are then called ideas of recollection ; and are performed with ftrength and velocity in pro- portion to the energy of the volition that excites them, and the quantity of fenforial power. II. i. The mufcular motions above defcribed, that are moft frequently obedient to the will, are neverthelefs occaiionally caufable by painful or plea- furable fenfation, as in the ftarting from fear, and the contraction of the calf of the leg in the cramp. 2. In like manner the fenfual motions, or ideas, that are moft frequently connected with volition, are neverthelefs occafionally caufable by painful or pleafurable fenfation. As the hifiories of men, or the defcription of places, which we have volunta- rily taken pains to remember, fometimes occur to us in our dreams. Hi. i. The mufcular motions that are generally fubfervient to volition, are alfo occafionally caufa- ble by irritation, as in ftretching the limbs after fleep, and yawning. In this manner a contraction of the arm is produced by paffing the electric fluid from SECT. IX. 4. VOLUNTARY MOTIONS. 49 from the Leyden phial along its rnufcles ; and that even though the limb is paralytic. The fudden motion of the arm produces a difagreeable fenfation in the joint, but the mufcles feein to be brought into aclion (imply by irritation. 2. The ideas, that are generally fubfervient to the will, are in like manner occafionally excited by irritation ; as when we view again an object, we have before well ftudied, and often recollected. IV. i. Innumerable trains or tribes of motions are affociated with thefe voluntary mufcular mo- tions above mentioned ; as when I will to extend my arm to a diftant object, fome other mufcles are brought into action, and preferve the balance of my body. And when I wi(h to perform any fleady exertion, as in threading a needle, or chopping with an ax, the pectoral mufcies are at the iame time brought into action to preferve the trunk of the body motionlefs, and we ceafe to refpire for a time. 2. In like manner the voluntary fenfual motions, or ideas of recollection, are affociated with many other trains or tribes of ideas. As when I volunta- rily recollect a gothic window, that I faw fome time ago, the whole front of the cathedral occurs to me at the fame time. SECT. 5* -ASSOCIATE MOTIONS. SECT. X. i. SECT. X. OF ASSOCIATE MOTIONS. I, i . Many mufcular motions excited by irritations in . trains or tribes become officiated. 2. A W many ideas. II. i. Many fenfitive mufcular motions become af- fociated. ^• And many fenfitive ideas . III. i. Many voluntary mufcular motions become officiated. 2. And then become obedient to fenfation or irritation. 3. And many voluntary ideas become officiated* ALL the fibrous motions, whether mufcular or fenfual, which are frequently brought into action together, either in combined tribes, or in fucceflive trains, become fo connected by habit, that when one of them is reproduced the others have a tendency to fucceed or accompany it. I. i. Many of our mufcular motions were ori- ginally excited in fucceflive trains, as the contrac- tions of the auricles and of the ventricles of the heart ; and others in combined tribes, as the vari- ous divifions of the mufcles which compofe the calf of the leg, which were originally irritated into fyn- chronous action by the txdium or irkfomenefs of a continued pofture. By frequent repetitions thefe motions acquire affociations, which continue dur- ing our lives, and even after the deftruction of the greateft part of the fenforium ; for the heart of a viper or frog will continue to puifate long after it is taken from the body -, and when it has entirely ceafed to move, if any part of it is goaded with a pin, the whole heart will again re- new its pulfations. This kind of connection we fliall term irritative aflbciation, to diftinguifli it from fenfitive and voluntary aflbciations. 2. In SECT. X. 2. ASSOCIATE MOTIONS. 5r 2. In like manner many of our ideas are origi- nally excited in tribes ; as all the objects of fight, after we become fo well acquainted with the laws of vifion, as to diftinguifli figure and diftance as well as colour ; or in trains, as while we pafs along the objects that furround us. The tribes thus receiv- ed by irritation become affociated by habit, and have been termed complex ideas by the writers of metaphyfics, as this book or that orange. The trains have received no particular name, but thefe are alike affociations of ideas, and frequently con- tinue during our lives. So the tafte of a pine-ap- ple, though we eat it blindfold, recalls the colour and fhape of it ; and we can fcarcely think on foli- dity without figure. II. i. By the various efforts of our fenfations to acquire or avoid their objects, many mufcies are daily brought into fucceffive or fynchronous ac- tions ; thefe become ailociated by habit, and £re then excited together with great facility, and in many inftances gain indiflbluble connections. So the play of puppies and kittens is a reprefentation of their mode of fighting or of taking their prey ; and the motions of the mufcles neceflary for thofe purpoies become afibciated by habit, and gain a great adroitnefs of action by thefe early repetitions : fo the motions of the abdominal mufcles, which were originally brought into concurrent action with the protrufive motion of the rectum -or bladder by ienfation, become fo conjoined v/ith them by habit, that they not only eafily obey thefe fenfations occa- iioned by the ftimulus of the excrement and urine, but are brought into violent and unreftrainable ac- tion in the ftrangury and tenefmus. This kind of connection we mall term fenfitive aflbciation. 2. So many of our ideas, that have been excited together or in fucceffion by our fenfations, gain fynchronous or fucceffive aflbciations, that are fome- tiaies 52 ASSOCIATE MOTIONS. SECT. X. 3. times indiflbluble but with life. Hence the idea of an inhuman or difhonourable action perpetually calls up before us the idea of the wretch that was guilty of it. And hence thofe unconquerable anti- pathies are formed, which forne people have to the fight of peculiar kinds of food, of which in their in- fancy they have eaten to excefs or by conftraint. III. i. In learning any mechanic art, as mufic, dancing, or the ufe of the fword, we teach many of our mufcles to act together or in fucceflion by repeated voluntary efforts ; which by habit become formed into tribes or trains of aflbciation, and ferve all our purpofes with great facility, and in fome in- fiances acquire an indiflbluble union. Thefe mo- tions are gradually formed into a habit of acting to- gether by a multitude of repetitions, whilft they are yet feparately caufable by the will, as is evident from the long time that is taken up by children in learning to walk and to fpeak ; and is experienced by every one, when he firil attempts to fkate upon the ice or to fwim; thefe we lhali term voluntary affociation s. 2. All thefe mufcular movements, when they are thus aflbciated into tribes or trains, become after- wards not 'only obedient to volition, but to the fen- fations and irritations ; and the fame movement compofes a part of many different tribes or trains of motions. Thus a fingle mufcle, when it acts in confort with its neighbours on one fide, aflifts to move the limb in one direction ; and in another, when it acts with thofe in its neighbourhood on the other fide ; and in other directions, when it acts Separately or jointly with thofe that lie immediately under or above it ; and all thefe with equal facility after their aflbciations have been well eftablifhed. The facility, with which each mufcle changes from one aflbciated tribe to another, and that either backwards or forwards, is well obfervable in SECT. X. 3. ASSOCIATE MOTIONS, 5$ in the mufcles of the arm in. moving the \vind- lafs of an air-pump ; and the ilownefs of thofe mufcular movements, that have not been aflbciated by habit, may be experienced by any one, who fliall attempt to faw the air quick perpendicularly with one hand, and horizontally with the other at the fame time. 3. In learning every kind of fcience we volunta- rily affociate many tribes and trains of ideas, which afterwards are ready for all the purpofes either of volition, fenfation, or irritation ; and in (bine in- ftances acquire indiffolubie habits of acting together, fo as to affect our reafonjng, and influence our ac- tions. Hence the neceflity of a good education. Thefe affociate ideas are gradually formed into habits of acting together by frequent repetition, while they are yet feparately obedient to the will; as is evident from the difficulty we experience in gaining fo exact an idea of the front of St. Paul's church, as to be able to delineate it with accuracy, or in recollecting a poem of a few pages. And thefe ideas, thus affociated into tribes, not only make up the parts of 'the trains of volition, fenfation, and irritation ; but the fame idea com- pofes a part of many different tribes and trains of ideas. So the firnple idea of vvhitenefs compofes a part of the complex idea of mow, milk, ivory j and the complex idea of the letter A compofes a part of the feveral affociated trains of ideas that make up the variety of words, in which this letter enters. The numerous trains of thefe affociated ideas are divided by Mr. Hume Into three claffes, which he has termed contiguity, caufation, and refemblance. Nor mould we wonder to find them thus connected together, fmce it is the bufinefs of our lives to dif- pofe them into thefe three claffes ; and we become valuable to ourfelves and our friends, as we fucceed in 54 SENSORIAL ACTIONS. SECT. XI. r. in it. Thofe who have combined an extenfive clafs of ideas by the contiguity of time or place, are men learned in the hiftory of mankind, and of the fcien- ces they have cultivated. Thofe who have connedl- ed a great clafs of ideas of refemblances, pofTefs the fource of the ornaments of poetry and oratory, and of all rational analogy. While thofe who have con- nected great chffes of ideas ofcaufation, are furnifh- ed with the powers of producing effects. Thefe are the men of a&ive wifdom. who lead armies to vic- tory, and kingdoms to profperty ; or difcover and improve the fciences, which meliorate and adorn the condition of humanity. SECT. XI. ADDITIONAL OBSERVATIONS ON THE SENSORIAL POWERS. I. Stimulation is of various kinds adapted to the organs of fenfe, to the mufcles, to hollow membranes, and glands. Some chjctts irritate our fenfes by repeated impulfes. 11. i. Senfation and volition frequently ajjeft the whole fenjorium. 2. Emotions, pajfions, appetites. 3. Origin of .defire and aver/ton. Grite* rion of voluntary actions, difference of brutes and men. 4. Senfib'dityandvoluntarity. III. Affociations form- ed before nativity -, irritative motions miftakenfor af- fociatcd ones. Irritation. I. THE various organs of fenfe require various kinds of flimulation "to excite them into action ; the SECT. XL i; SENSORIAL ACTIONS, 55 the particles of light penetrate the cornea and hu- mours of the eye, and then irritate the naked reti- na ; fapid particles, diffolved or diffufed in water or faliva, and odorous ones, mixed or combined with the air, irritate the extremities of the nerves of tafle and fmeli j which either penetrate, or are expanded on the membranes of the tongue and nof- trils ; the auditory nerves are ilimulated by the vi- brations of the atmofphere communicated by means of the tympanum and of the fluid, whether of air or of water, behind it ; and the nerves of touch by the hardnefs of furrounding bodies, though the cu- ticle is interpofed between thefe bodies and the me- dulla of the nerve. As the nerves of the fenfes have each their appro- priated objects, which flimulate them into activity ; fo the mufcular fibres, which are the terminations of other fets of nerves, have their peculiar objects, which excite them into action ; the longitudinal mufcles are ftimulated into contraction by exten- lion, whence the ftretching orpandiculation after a long continued pofture, during which they have been kept in a ftate of extenfion ; and the hollow mufcles are excited into action by diftention, as thofe of the rectum and bladder are induced to pro- trude their contents from their fenfe of the diften- tion rather than of the acrimony of thole con- tents. There are other objects adapted to ftimulate the nerves, which terminate in a variety of membranes, and thofe efpecialiy which form the terminations of canals ; thus the preparations of mercury particu- larly affect the falivary glands, ipecacuanha the (to- mach, aloe the fphincter of the anus, cantharides that of the bladder, and laftly every gland of the body appears to be indued with a kind of tafte, by which it felects or forms each its peculiar fluid from the blood j and by which it is irritated into acti- vity. Many 5$ SENSORIAL ACTIONS. SECT. XT. *J Many of thefe external properties of bodies, which ftimulate our organs of fenfe, do not feem to effect this by a fingle impulfe, but by repeated impulfes ; as the nerve of the ear is probably not excitable by a fingle vibration of air, nor the optic nerve by a lingle particle of light ; which circumftance pro- duces fome analogy between thofe two fenfes, at the fame time the fblidity of bodies is perceived by a fingle application of a folid body to the nerves of touch, and that even through the-cuticle; and we are probably poffeiTed of a peculiar fenfe to diftin- guifli the nice degrees of heat and cold. The fenfes of touch and of hearing acquaint us with the mechanical impact and vibration of bodies, thofe of fmell and tafle feem to acquaint us with fome of their chemical properties, while the fenfe of vifion and of heat acquaint us with the exigence of their peculiar fluids. Senfation and Volition. II. Many motions are produced by pleafure or pain, and that even in contradiction to the power of volition, as in laughing, or in the ftrangury ; but as no name has been given to pleafure or pain, at the time it is exerted fo as to caufe fibrous mo- tions, we have ufed the term fenfation for this pur- pofe ; and mean it to bear the fame analogy to plea- lure and pain,vthat the word volition does to defire and averfion. i. It was mentioned in the fifth Section, that, what we have termed fenfation is a motion of the central parts, or of the whole fenforium, beginning at fome extremities of it. This appears firit, be- caufe our pains and pleafures are always caufed by our ideas or mufcular motions, which are the mo- tions of the extremities of the fenforium. And, fccondly, becaufe the fenfation of pleafure or pain frequently "«ECT. XI. 2. SENSOKIAL ACTIONS. 57 frequently continues fome time after the ideas or mufcular motions which excited it have ceafed: for we often feel a glow of pleafure from an agree- able reverie, for many minutes after the ideas, that were the fubject of it, have efcaped our memory ; and frequently experience a dejectiotyof fpirits with- out being able to ailign the caufe of it but by much recolleclion. When the fenforial faculty of defire or averfion is exerted fo as to caufe fibrous motions, it is term- ed volition ; which is faid in Seel. V. to be a mo- tion of the central parts, or of the whole fenforium, terminating in fome of the extremities of it. This appears, firft, becaufe our defires and averfions al- ways terminate in recollecting and comparing our ideas, or in exerting our mufcles ; which are the motions of the extremities of the fenforium And, fecondly, becaufe defire or averfion begins, and frequently continues for a time in the central parts of the fenforium, before it is peculiarly exerted at the extremities of it ; for we fometimes feel defire or averfion without immediately knowing their objects, and in confequence without immediately exerting any of our mufcular or fenfual motions to attain them : as in the beginning of the paflion of love, and perhaps of hunger, or in the ennui of indolent people. Though ienfation and volition begin or termi- nate at the extremities or central parts of the fen- forium, yet the whole of it is frequently influenced by the exertion of thefe faculties, as appears from their effects on the external habit : for the whole fkin is reddened by mame, and an univeral tremb- ling is produced by fear : and every mufcle of the body is agitated in angry people by the defire of revenge. There is another ver ycurious circumftance, which {hews that fenfation and volition are movements of the 58 SENSORIAL ACTIONS. SECT. XL 2. the fenforium in contrary directions ; that is, that volition begins at the central parts of it, and pro- ceeds to the extremities ; and that fenfation begins at the extremities, and proceeds to the central parts : I mean that thefe two fenforial faculties cannot be ftrongly exerted at the fame time ; for when we exert our volition ftrongly, we do not attend to pleafure or pain ; and converfely, when we are itrongly affected with the fenfation of pleafure or pain, we u(e no volition. As will be further ex- plained in Section XVIII. on fleep, and Section XXXIV. on volition. 2. All our emotions and paflions feem to arife out of the exertions of thefe two faculties of the animal fenforium. Pride, hope, joy, are the names .of particular pleafures : ihame, defpair, forrow, arc the names of peculiar pains : and love, ambition, avarice, of particular defires : hatred, difguft, fear, anxiety, of particular averfions. Whilft the paf- lion of anger includes the pain from a recent injury, and the averfion to the adverfary that occaiioned it. And companion is the pain we experience at (the fight of mifery, and the defire of relieving it. There is another tribe of defires, which are com- monly termed appetites, and are the immediate confequences of the abfence of fome irritative mo- tions. Thofe, which arife from defect of internal irritations, have proper names conferred upon them, as hunger, thirft, luft, and the defire of air, when our refpiratipn is impaired by noxious va- pours ; and of warmth, when we are expofed to too great a degree of cold. But thofe, whofe fti- niuli are external to the body, are named from the objects, which are by nature conftituted to excite them ; thefe defires originate from our paft expe- rience of the pleafurable fenfations they occafion, as SECT. XI. 2. SENSORIAL ACTIONS. 59 as the fmell of an hyacinth, or the tafte of a pine- apple. Whence it appears, that our pleafures and pains are at leaft as various and as numerous as our irri- tations ; and that our defires and averfions muft be as numerous as our pleafures and pains. And that as fenfation is here ufed as a general term for our numerous pleafures and pains, when they produce the contractions of our fibres ; fo volition is the general name for our defires and averfions, when they produce fibrous contractions. Thus when a motion of the central parts, or of the whole fenfo- rium, terminates in the exertion of our mufcles, it is generally called voluntary aftion ; when it ter- minates in the exertion of our ideas, it is termed recolledion, reafoning, determining. 3. As the fenfations of pleafure and pain are ori- ginally introduced by the irritations of external ob- jects : fo our defires and averfions are originally in- troduced by thofe fenfations ; for when the obje<5ts of our pleafures or pains are at a diftance, and we cannot inftantaneoufly poflefs the one, or avoid the other, then defire or averfion is produced, and a voluntary exertion of our ideas or mufcles fuc- ceeds. The pain of hunger excites you to look out for food, the tree, that (hades you, prefents its odori- ferous fruit before your eyes, you approach, pluck, and eat. The various movements of walking to the tree, gathering the fruit, and mafticating it, are afTo- elated motions introduced by their connexion with ienfation -, but if from the uncommon height of the tree, the fruit be inacceilible, and you are prevent- ed from quickly poffefling the intended pleafure, defire is produced. The confequence of this defire is, firft, a deliberation about the means to gain the objeft of pleafure in procefs of time, as it cannot F be €o SENSORIAL ACTIONS. Srcr; XI. * be procured immediately ; and, fecondly, the muf- cular action necefiary for this purpofe. You voluntarily call up all your ideas of caufa- tion, that are related to the effect you defire, and voluntarily examine and compare them, and at length determine whether to afcend the tree, or to gather ftones from the neighbouring brook, is eaiier to praclife, or more promiling of fuccefs ; and, finally, you gather the ftones, and repeatedly fling them to diflodge the fruit. Hence then we gain a criterion to diftinguifh voluntary acts or thoughts from thofe caufed by fenfation » As the former are always employed about the means to acquire pleafurable objects, or the means to avoid painful ones ; .while the latter are employed in the pofleffiun of thofe, which are already in our power. Hence the activity of this power of volition pro- duces'the great difference between the human and the brute creation. The ideas and the actions of brutes are almoft perpetually employed about their prefent pleafures, or their prefent pains ; and, except In the few inftances which are mentioned in Sec- tion XVI. oh inftinct, they feldom bufy themfelves about the meansof procuring future blifs, orof avoid- ing future mifery ; fo that the acquiring of lan- guages, the making of tools, and labouring for jmoney, which are all only the means to procure pleafures ; and the praying to the Deity, as another means to procure happinefs, are character! (tic of human nature. 4. As there are many difeafes 'produced by the quantity of the fenfation of pain or pleafure being too great or too little ^ fo are there difeafes produc- ed by the fufceptibility of the conftitution to mo> tions caufable by thefe fenfation s being too dull or too vivid. This fufceptibility of the fyftem to fen- iitive motions is termed fenfibility, to diftinguifh it from SECT. XI. 3. SENSORIAL ACTIONS 61 from fenfation, which is the actual exiftence or exertion of pain or pleafure. Other dalles of difeafes are owing to the excef- five promptitude, or fluggiflinefs of the conftitu- tion to voluntary exertions, as well as to the quan- tity of defire or of averfion. This fufceptibility of the fyftem to voluntary motions is termed volun- tarity, to diftinguifh it from volition, which is the exertion of defire or averfion ; thefe difeafes will be treated of at length in the progrefs of the work. Affbd&tltih* III. t. It is not eafy to aflign a caufe, why thofe animal movements, that have once occurred in fuc- ceflion, or in combination, mould afterwards have a tendency to fucceed or accompany each other. It is a property of animation, and diftinguifhes this order of being from the other productions of na- ture. When a child firft wrote the word man, it was diftingui/hed in his mind into three letters, and thofe letters into many parts of letters ; but by re- peated ufe the word man becomes to his hand in writing it, as to his organs of fpeech in pronounc- ing it, but one movement without any delibera- tion, or fenfation, or irritation, interpofed between the parts of it. And as many feparate motions of our mufcles thus become united, and form, as it were, one motion ; fo each feparate motion before fuch union may be conceived to confift of many parts or fpaces moved through ; and perhaps even the individual fibres of our mufcles have thus gradually been brought to act in concert, which habits began to be acquired as early as the very formation of the moving organs, long before the nativity of the animal \ as explained in the Se&ion XVI. 2. on in- ftincl. F 2 a. There «J SENSORIAL ACTIONS. Seer. XI. £ 2. There are many motions of the body, belong- ing to the irritative elafs, which might by a hafty obferver be miftaken for aflbciated ones ; as the pe- riftaltic motion of the ftomach and inteftines, and the contrasclrons of the heart and arteries, might be fuppofed to be aflbciated with the irritative motions of their nerves of fenfe, rather than to be excited by the irritation of their mufcular fibres by the dif- tention, acrimony, or momentum of the blood. So the diftention, or elongation of mufcles by objects external to them irritates them into con- traction, though the cuticle or other parts may Intervene between the ftimulating body and the contracting mufcle. Thus a horfe voids his excre- ment when its weight or bulk irritates the rectum or fphincter ani. Thefe mufcles act from the irri- tation of diftention, when he excludes his excre- ment, but the mufcles of the abdomen and diaph- ragm are brought into motian by aflbciation with thofe of the fphincler and rectum. SECT. XII. OF STIMULUS, SENSORIAL EXERTION*, AND FIBRQU& CONTRACTION. I. Of fibrous contraction, i. Two particles of a Jibre cannot approach without the intervention offomething, as in magnet if in, ele£lricity+ elajlicity. Spirit of life is net ekftric ether. G ah ant's experiments. 2. Con- traftion of ajibre. 3. Relaxation fucceeds. 4. Sue- ceffi've contractions, with intervals. Quick pulfe from debility ) from paucity of blood* W€ak contractions per- formed SSCT. XIL OF STIMULUS AND EXERTION. 63 formed In lefs time, and with Jhorter intervals. 5. 5. Laft fituation of the fibres continues after contrac- tion. 6. Contraction greater than ufual induces plea- fure or pain. 7. Mobility of the fibres uniform. Quantity cf fenforial power fluctuates. Constitutes excitability. If. Of fenforial exertion. \.Animal motion includes Jlimulus^ fenforial power ^ and contrac- tile fibres. The fenforial faculties aft feparately or conjointly. Stimulus of four kinds. Strength and iveaknefs defined. Senforial power perpetually exkauft- *d and renewed. Weakncfs from defeci of ftimulus* From defeci of fenforial power , the dirett and indired debility of Dr. Brown. Why we become warm in Bux- ion bath after a time^ and fee well after a time in a darkifh room, fibres may aft violently , or with their •wl^ole force ', and yet feebly. Great exertion in inflam- mation explained. Great ?nufcular force of fome in- fane people 2. Occqfional accumulation cf fenforial power in mufcles fubjeft to conft ant Jlimulus. In ani- mals Jleeping in winter. In eggs, feeds, fchirrous tu- mours, tendons y bones. 3. Great exertion introduces pleafure or pain. Inflammation. Libration of the fyjlem between torpor and activity. Fever-Jits. 4. Defire and averfion introduced. Excefs of volition tures fevers. III. Of repeated ftimulus. i. A Jlimulus repeated too frequently lofes effect. As opium, wine, grief. Hence old age. Opium and aloes in fmall dofes. 2. Ajtimulus not repeated too frequently does not lofe effect. Perpetual movement of the vital organs. 3. Ajlimulus repeated at uniform times produces greater effecl. Irritation combined 'with affbciation. 4. Ajlimulus repeated frequently and uniformly may be withdrawn, and the action of the organ will con- tinue. Hence the bark cures agues 9 andftrengthens weak conjlitutions . 5. Defeci, of Jlimulus repeated at certain intervals caufes fever-Jits. 6. Stimulus long applied ceafes to aft afecond time. 7. If a Jlimulus excites fenjation in an organ not ufually excited into fen- *4 OF STIMULUS AND EXERTION. SECT. XII. fation. Inflammation is produced. IV. Of ftimulus greater than natural, i. A Jiimulus greater than natural diminifhes the quantity of fenforial power in in general. 2. In particular organs. ^3. Induces the crgan into fpafmodic actions. 4. Induces the antago- ntft fibres into aflion. 5. Induces the organ into con- •vulfive or fixed fpafms. 6. Produces paralyfis of the organ. V. Of ftimulus lefs than natural, i- Sti- mulus lefs than natural occafions accumulation of fen- forial power in general 2. In particular organs, Jlujhing of the face in a frojiy morning. In fibres fub- jed to. perpetual Jiimulus only. Quantity of fenforial •power inverfely as the ftimulus. 3. Induces pain. As of cold, hunger 9 head-ach. 4. Induces more feeble and frequent contraction. As in low fevers. Which are frequently owing to. deficiency ef fenforial power rather than to deficiency G>f Jiimulus. 5. Inverts fuc- ceffive trains of motion. Inverts ideas. 6. Induces faralyfis and death. VI. Cure of increafed exer- tion, i. Natural cure of exhaujlion of fenforial power. 2. Decreafe the irritations. Venefedion. Cold. Abftinence. 3. Prevent the previous cold fit. Opium. Ear k. Warmth. Anger. SurpHfe. 4, Ex- cite fome other part of the fyjiem. Opium and warm bath relieve pains both from defcft and from excefs of Jiimulus. 5. Fir/I increafe the Jiimulus above, and then decreafe it beneath the natural quantity. VII. Cure of decreafed exertion, i. Natural cure by- accumulation of fenforial power. Ague-fits. Syncops\ 2. Increafe the Jiimulation^ by wine^ opium, given fo as not to intoxicate. Cheerful ideas. 3. Change the kinds of Jiimulus. 4. Stimulate the officiated or- gans. Blifters of ufe in heart-burn, and cold extre- mities. 5. Decreafe thejlimulation for a time, cold bath. 6. Decreafe the Jlimulation below natural, and then increafe it above natural* Bark after eme- tics. Opium after venefeftion. Praclice of Sy den- ham in chlorofis. 7. Prevent unneceffary expenditure of fenjorial power. Decumbent pofture, ftlence> dark- nefs. SECT. XII. i. OF STIMULUS AND EXERTION. 65 nefs. Pulfe quickened by rifing out of bed. 8. To the greateft degree of quiefcence apply the leajl flimulus. Giherwife paralyfts or inflammation of the organ en- fues. Gin, wine, blifters^ dejlroy by too great ftimu- lation in fevers with debility. Intoxication in the Jlightejl degree fucceeded by debility. Golden rule for determining the beft degree of ftimulus in low fevers. Another golden rule for determining the quantity of fpint, which thofe, who are debilitated by drinking it, may fafely omit. I. Of Jibrous contraclion. t. IF two particles of iron lie near each. other without motion, and after wards approach each other; it is reafonable to conclude that fomething befides the iron particles is the caufe of their approxima- tion ; this invifible fomething is termed magnetifm. In the fame manner, if the particles, which com- pofe an animal muicle, do not touch other in the relaxed ftate of the mufcle, and are brought into contact during the contraction of the mufcle ; it is reafbnable to conclude, that fome other agent is the caufe of this new approximation. For nothing can act, where it does not exift ; for to act includes to exift ; and therefore the particles of the mufcu- lar fibre (which in its ftate of relaxation are fup- pofed not to touch) cannot affect each other with- out the influence of fome intermediate agent ; this agent is here termed the fpirit of animation, or fenforiai power, but may with equal propriety be termed the power, which caufes contraction ; or may be called by another name, which the reader may choofe to affix to it. The contraction of a mufcular fibre may be com- pared to the following electric experiment, which is here mentioned not as a philotbphical analogy, but as an illuftration or fimile. to facilitate the coo* ceptioji 66 OF STIMULUS AND EXERTIOM. SECT. XIL i. ception of a difficult fubject. Let twenty very fmall Leyden phials properly coated be hung in a row by fine filk threads at a fmall diftance from each other ; let the internal charge of one phial be pofitive, and of the other negative alternately, if a communica- tion be made from the internal furface of the firft to the external furface of the laft in the row, they will all of them inftantly approach each other, and thus fhorten a line that might connect them like a mufcular fibre. See Botanic Garden, p. i. Canto I. 1. 202, note on Gymnotus. The attractions of electricity or of magnetifm do not apply philofophically to the illuftration of the contraction of animal fibres, fince the force of thofe attractions increafes in feme proportion inverfely as the diftance, but in mufcular motion there appears no difference in velocity or ftrength during the be- ginning or end of the contraction, but what may be clearly afcribed to the varying mechanic advan- tage in the approximation of one bone to another. Nor can mufcular motion be affimilated with great- er plaufibility to the attraction of cohefion or elaf- ticity ; for in bending a fteel fpring, as a fmall fword, a lefs force is required to bend it the firft inch than the fecond ; and the fecond than the third; the particles of fteel on the convex fide of the bent fpring endeavouring to reftore themfelves more powerfully the further they are drawn from each other. See Botanic Garden, P. i. addit. Note XVIII. I am aware that this may be explained another way, by fuppofing the elalHcity of the fpring to depend more on the compreffion of the particles on the concave fide than on the extenfion of them on the convex fide ; and by fuppofing the elafticity of the elaltic gum to depend more on the refiftance to the lateral ^compreilion of its particles than to the longitudinal extenfion of them. Neverthelefs in mufcular SECT. XII. i. OF STIMULUS AND EXERTION. 67 mufcular con traction, as above obferved, there ap- pears no difference in the velocity or force of it at irs commencement or at its termination ; from whence we muft conclude that animal contraction is governed by laws of its own, and not by thofe of mechanics, chemiftry, magnetifm, or electri- city. On thefe accounts I do not think the experiments conclufive, which were lately publiihed by GaUani, Volta, and others, to fhew a fiinilitude between the fpirit of animation, which contracts the inulcular fibres, and the electric fluid. Since the electric fluid may act only as a more potent ftimukis exciting the mufcular fibres into action, and not by fupply- ing them with a new quantity of the fpirit of life. Thus in a recent hemiplegia I have frequently ob- ferved, when the patient yawned and ftretched himfelf, that the paralytic limbs moved alfo, though they were totally difobedient to the will. And when he was electrified by parting fhocks from the affected hand to the affected foot, a motion of the paralytic limbs was alfo produced. Now as in the act of yawning the mufcles of the paralytic limbs were excited into action by the Itimulus of the irk- fomenefs of a continued pofture, and not by any additional quantity of the fpirit of life; fo we may conclude, that the paffage of the electric fluid, which produced a limilar effect, acted only as a fti- mulus, and not by fupplyingany addition of fenfb- rial power. If neverthelefs this theory fhould ever become eftablifhed, a ftimulus muft be called an eductor of vital ether ; which ftimulus may con lift of lenfati- on or volition, as in the electric eel, as well as in the appuites of external bodies ; rwd by drawing off the charges of vital fluid may occalion the contrac- tion or motions of the mufcular fibre s, and organs of fenfe. a. 'The €8 OF STIMULUS AND EXERTION. Sscr.XIL U 2. The immediate effect of the action of the fpi- rit of animation or fenforial power on the fibrous* parts of the body, whether it acts in the mode of irritation, ienfation, volition, or afTociation, is a contraction of the animal fibre, according to the fecond law of animal caufation. Seel. IV. Thus the ftinnulus of the blood induces the contraction of the heart ; the agreeable tafte of a ftrawberry produces the contraction of the mufcles of deglu- tition ; the effort of the will contracts the mufcles, which move the limbs in walking; and by affocia- tion other mufcles of the trunk are brought into contraction to preferve the balance of the body. The fibrous extremities of the organs of fenfe have been fliewn, by the ocular fpectra in Seel. III. to fuffer iimilar contraction by each of the above modes of excitation ; and by their configurations to conftitute our ideas, 3. After animal fibres have for fome time been excited into contraction, a relaxation fucceeds, even though the exciting caufe continues to act. In re- fpecl to the irritative motions this is exemplified in the periftaltic contractions of the bowels ; which ceafe and are renewed alternately, though the fti- mulus of the aliment continues to be uniformly ap- plied ; in the fenfitive motions, as in ftrangury, tenefmus, and parturition, the alternate contracti- ons and relaxations of the mufcles exift, though the ftimulus is perpetual. In our voluntary exer- tions it is experienced, as no one can hang long by the hands, however vehemently he wills io to do; and in the aflbciate motions the conftant change of our attitudes evinces .the neceflity of relaxation to thofe mufcles, which have been long^n action. This relaxation of a mufcle after its contraction, even though the ftimulus continues to be applied, appears to arife from the expenditure or diminution pf the fpirit of animation previoufly refidem in the SECT. XII. i. OF STIMULUS AND EXERTION. 69 mufcle, according to the fecond law of animal cau- fation in Sect. IV. In thofe conftitutions, which are termed weak, the fpirit of animation becomes fooner exhaufted, and tremulous motions are pro- duced, as in the hands of infirm people, when they lift a cup to their mouths. The quicker cxhauft- ion of the fpirit of animation is probably owing to a lefs quantity of it refiding in the acting fibres, which therefore more frequently require a fupply from the nerves, which belong to them. 4. If the fenforial power continues to act, whe- ther it acts in the mode of irritation, fenfation, volition, or aflbciation, a new contraction of the animal fibre fucceeds after a certain interval; which interval is of fhorter continuance in weak people than in ftrong ones. This is exemplified in the fhaking of the hands of weak people, when they attempt to write. In a manuscript epiftle of one of rny correfpondents, which is written in a fmall hand, I obferved from four to fix zigzags in the perpendicular ftroke of every letter, which mews that both the contractions of the fingers, and in- tervals between them, muft have been performed in very (hort periods of time. The times of contraction of the mufcles of en- feebled people being lefs, and the intervals between thofe contractions being lefs alfo, accounts for the quick pulfe in fevers with debility, and in dying animals. The fhortnefs of the intervals between one contraction and another in weak conftitutions, is probably owing to the general deficiency of the quantity of the fpirit of animation, and that there- fore there is a lefs quantity of it to be received at each interv/* of the activity of the fibres. Hence in repeated motions, as of the fingers in perform- ing on the harpfichord, it would at firfi fight ap- pear, that fwiftnefs and ftrength were incompati- ble ; neverthelefs the fmgle contraction of a mufcle b 7*> OF STIMULUS AND EXERTION. SECT. XII I. is performed with greater velocity as well as with greater force by vigorous confutations, as in throw- ing a javelin. There is however another circumftance, which may often contribute to caufe the quicknefs of the puiie in nervous fevers, as in animals bleeding to death in the Daughter- houie ; which is the deficient quantity of blood ; whence the heart is but half diftended, and in confequence fooner contracts. See Seel. XXXIL 2- i. For we muft not confound frequency of repeti- tion with quicknefs of motion, or the number of pulfations with the velocity, with which the fibres, which conftitute the coats of the arteries, contract themfelves. For where the frequency of the pul- fations is but feventy-five in a minute, as in health ; the contracting fibres, which conftitute the fides of the arteries, may move through a greater fpace in a given time, than where the frequency of pulfation is one hundred and fifty in a minute, as in fome fevers with great debility. For if in thofe fevers the arteries do not expand themfelves in their diaftole to more than half the ufual diameter of their diaflole in health, the fibres whkh conftitute their coats, will move through a lefs fpace in a mi- nute than in health, though they make two pulfa- tions for one. Suppofe the diameter of the artery during its fyftole to be one line, and that the diameter of the fame artery during its diaftole is in health is four lines, and in a fever with great debility only two lines. It follows, that the arterial fibres contract in health from a circle of twelve lines in circumfe- rence to a circle of three lines in c'^u inference, that is they move through a fpace of nine lines in length. While the arterial fibres in the fever with debility would twice contract from a circle of fix lines to a circle of three lines j that is while they move SECT. XII. r. OF STIMULUS AND EXERTION. 71 move through a fpace equal to fix lines. Hence though the frequency of pulfation in fever be greater as two to one, yet the velocity of contrac- tion in health is greater as nine to fix, or as three to two. On the contrary in inflammatory difeafes with ftrength, as in the pleuriiy, the velocity of the contracting fides of the arteries is much greater than in health, for if we fuppofe the number of pulfations in a pleurify to be half as much more than in health, that is as one hundred and twenty to eighty, (which is about what generally happens in inflammatory difeafes) and if the diameter of the artery in diaftole be one third greater than in health, which I believe is near the truth, the re* fult will be, that the velocity of the contractile fides of the arteries will be in a pleurify as two and a half to one, compared to the velocity of their contrac- tion in a ftate of health, for if the circumference of the fyftole of the artery be three lines, and the diaftole in health be twelve lines in circumference, and in a pleurify eighteen lines ; and fecondly, if the artery pulfates thrice in the difeafed ftate for twice in the healthy onc« it follows, that the velo- city of contraction in the difeafed ftate to that in the healthy ftate will be forty-five to eighteen, or as two and a half to one. From hence it would appear, that if we had a criterion to determine the velocity of the arterial contractions, it would at the fame time give us their ftrength, and thus be of more fervice in diftinguifh- ing difeafes, than the knowledge of their fre- quency. As fuch a criterion cannot be had, the frequency of puifauon, the age of the patient being allowed for, will in ibme meafure affift us to diftin- guifli arterial ftrength from arterial debility, fince in inflammatory difeafes with ftrength the frequency feldotn exceeds one hundred and eighteen or one hundred 72 OF STIMULUS AND EXERTION. SECT.*!/. i<* hundred and twenty pulfations in a minute ; unlefs under peculiar cir cum fiance, as the great additional ftimuli of wine or of external heat. 5. After a mufcle or organ of fenfe has been ex- cited into contraction, and the fenforial power ceafes to act, the laft fituation or configuration of it con- tinues ; unlefs it be diftributed by the action of fome antagonift fibres, or other extraneous power* Thus in weak or languid people, wherever they throw their limbs on their bed or fofa, there they lie, till another exertion changes their attitude ; hence one kind of ocular fpectra feems to be pro- duced after looking at bright objects ; thus when a fire-flick is whirled round in the night, there ap- pears in the eye a complete circle of fire 5 the ac- tion or configuration of one part of the retina not ceafing before the return of the whirling fire. Thus if any one looks at the fetting fun for a fiiort time, and then covers his clofed eyes with his hand, he will for many feconds of time perceive the image of the fun on his retina. A fimilar image of all other bodies would remain fome time in the eye, but is effaced by the eternal change of the motions of the extremity <,f this nerve in our at- tention to other objects. See Sect. XVII. i. 3. on Sleep. Hence the dark fpots, and other ocular fpectra, are more frequently attended to, and re- main longer in the eyes of weak people, as after violent exercife, intoxication, or want of fleep. 6. A contraction of the fibres fomewhat greater than ufual introduces pleafurable feniation into the fyftern, according to the fourth law of animal cau- fation. Hence the pleafure in the beginning of drunkenneis is owing, to the incrcafed action of the fyftem from the flimulus of vinous fpirit or of opium. If the contractions be ftill greater in ener- gy or duration, painful fenfations are introduced, as SECT. XII. r. OF STIMULUS AND EXERTION. 7$ as in confequence of great heat, or cauftic applica- tions, or fatigue. If any part of the fyftem, which is ufed to per- petuai activity, as the ftomach, or heart, or the fine veffels of the (kin, acts for a time with lefs energy, another kind of painful fenfation enfues, which is called hunger, or faintnefs, or cold. This occurs in a lefs degree in the locomotive mufcles, and is called wearyfomenefs. In the two former kinds of fenfation there is an expenditure of fen- forial power, in thefe latter there is an accumulati- on of it. 7. We have ufed the words exertion of fenforial power as a general term to exprefs either irritation, fenfation, volition, or aflbciation ; that is, to ex- prefs the activity or motion of the fpirit of anima- tion, at the time it produces the contractions of the fibrous parts of the fyftem. It may be fuppofed that there may exift a greater or lefs mobility of the fibrous parts of our fyftem, or a propenfity to be ftimulated into contraction by the greater or lefs quantity or energy of the fpirit of animation ; and that hence if the exertion of the fenforial power be in its natural ftate, and the mobility of the fibres be increafed, the fame quantity of fibrous contra&ion will be caufed, as if the mobility of the fibres continues in its natural ftate, and the fenfo- rial exertion be increafed. Thus it may be conceived, that in difeafes ac- companied with ftrength, as in inflammatory fevers with arterial ftrength, that the eaufe of greater fibrous contraction may exift in the increafed mo- bility of the fibres, whofe contractions are thence both more forceable and more frequent. And that in difeafes attended with debility, as in nervous fevers, where the fibrous contractions are weaker, and more frequent, it may be conceived that the caufe confiftsin a decreafc of mobility of the fibres ; and 74 OF STIMULUS AND EXERTION. SECT. XII. i. and that thofe weak conftitutions, which are at. tended with cold extremities and large pupils of the eyes, may poiTefs lefs mobility of the contractile fibres, as well as lefs quantity of exertion of the fpirit of animation. In anfwer to this mode of reafoning it may be fufficient to obferve, that the contractile fibres con- fift of inert matter, and when the fenforial power is withdrawn, as in death, they poffefs no power of motion at all, but remain in their laft ftate, whe- ther of contraction or relaxation, and muft thence derive the whole of this property from the fpirit of animation. At the fame time it is not improbable, that the moving fibres of ttrong people may pof- fefs a capability of receiving or containing a greater quantity of the fpirit of animation than thofe of weak people. In every contraction of a fibre there is an expen- diture of the icnforial power, or fpirit of animati- on ; and where the exertion of this fenforial power Has been for fome time increafed, and the mufcles or organs of fenfe have in confequence acted with greater energy, its propenfity to activity is propor- tionally lefiened ; which is to be afcribed to the ex- hauftion or diminution of its quantity. On the contrary, where there has been lefs fibrous contrac- tion than ufual for a certain time, the fenforial power or animation becomes accumulated in the in- active part of the fyftem. Hence vigour fucceeds reft, and hence the propenfity to action of all our organs of (enfe and mufcles is in a ftate of perpe- tual fluctuation. The irritability for inftance of the retina, that is, its quantity of fenforial power, varies every moment according to the brightnefs or obfcurity of the object laft beheld compared with the prefent one. The fame occurs to our fenfe of heat, and to every part of our fyftem, which is capable of being excited into action. When SECT. XII. 2. OF STIMULUS AND EXERTION. 75 When this variation of the exertion of the fen- forial power becomes much and permanently above or beneath the natural quantity, it becomes a cifeafe. If the irritative motions be too great or too little, it fhews that the flimulus of external things affects this fenforial power too violently or too in- ertly. If the fenfitive motions be too great or too little, the caufe arifes from the deficient or exube- rant quantity of fenfation produced in confequence of the motions of the mufcuhr fibres or organs of fenfe; if the voluntary aclions are difeafed, the caufe is to be looked for in the quantity of volition produced in confequence of the defire or aversion occaiioned by the painful or pleafurable fenfations above mentioned. And the difeafes of afTociations probably depend on the greater or lefs quantity of the other three fenforial powers by which they were formed. From whence it appears that the propenfity to action, whether it be called irritability, fenfibility, voluntarity, or aflbciability, is only another mode of expreffion for the quantity of fenforial power re- fiding in the organ to be excited. And that on the contrary the words inirritability and inienfibility, together with inaptitude to voluntary and aflbciate motions, are fynonymous with deficiency of the quantity of fenforial power, or of the fpirit of animation, refiding in the organs to be excited. II. Of fenforial Exertion. i. There are three circumflances to be attended to in the production of animal motions, ift. The ftimulus. 2d. The fenforial power. 3d. The con- tractile fibre, i ft. A ftimulus, external to the or- gan, originally induces into action the fenforial fa- culty termed irritation ; this produces the contrac- tion of the fibres, which if it be perceived at all, G introduces 76 OF STIMULUS AND EXERTION. SECT. XII. 2- introduces pleafure or pain ; which in their active flate are termed fenfation ; which is another feiifo- rial faculty, and occafionally produces contraction of the fibres ; this pleafure or pain is therefore to be confidered as another ftimulus, which may either act alone or in conjunction with the former faculty of the fenforium termed irritation. This new fti-x mulus of pleafure or pain either induces into action the fenforial faculty termed fenfation, which then produces the contraction of the fibres ; or it intro- duces defire or averiion, which excite into action another fenforial faculty, termed volition, and may therefore be confidered as another ftimulus, which either alone, or in conjunction with one or both of the two former faculties of the fenforium, produces the contraction of animal fibres. There is another fenforial power, that of affociation, which perpetually, in conjunction with one or more of the above, and frequently fingly, produces the contraction of animal fibres, and which is itfelf excited into action by the previous motions of con- tracting fibres. Now as the fenforial power, termed irritation, refiding in any particular fibres, is excited into ex- ertion by the ilimulus of external bodies acting on thofe fibres; the fenforial power, termed fenfation, refiding in any particular fibres is excited into exer- tion by the (limulus of pleafure or pain acting on thofe fibres; the fenforial power, termed volition, refiding in any particular fibres is excited into ex- ertion by the ftimulus of deiire or averfion ; and the fenforial power termed affociation, refiding in any particular fibres, is excited into action by the iUmuius of other fibrous motions, which had fre- quently preceded them. The word ilimulus may therefore be ufed without impropriety of language, for any of thefe four caufes, which excite the four fenforial SECT. XII. 2. OF STIMULUS AND EXERTION. 77 fenforial powers into exertion. For though the immediate caufe of volition has generally been termed a motive ; and that of irritation only has generally obtained the name of ftimulus ; yet as the immediate caufe, which excites the fenforial powers of fenfation, or of aflbciation into exertion, have obtained no general name, we iliall ufc the word ftimulus for them all. Hence the quantity of motion produced in any particular part of the animal fyftem will be as the quantity of ftimulus and the quantity of fenforial power, or fpirit of animation, redding in the con- tracting fibres. Where both thefe quantities are great ftrength is produced, when that word is ap- plied to the motions of animal bodies. Where either of them is deficient, iveaknefs is produced, as applied to the motions of animal bodies. Now as the fenforial power, or fpirit of animati- on, is perpetually exhaufted by the expenditure of it in fibrous contractions, and is perpetually re- newed by the fecretion or production of it in the brain and fpinal marrow, the quantity of animal ftrength muft be in a perpetual (late of fluctuation on this account ; and if to this be added the un- ceafmg variation of all the four kinds of ftimulus above dcfcribed, which produce the exertions of the fenforiai powers, the ceafelefs viciffitude of animal ftrength becomes eafiiy comprehended. If the quantity of fenforial power remains the fame, and the quantity of ftimulus be leiTened, a weaknefs of the fibrous contractions enfues, which may be denominated debility from defeft of ftimulus. If the quantity of ftimuius remains the lame, and the quantity of fenforial power be leflened, another kind of weaknefs enfues, which may be termed debility frojn defefl of fenforial power ; the former of G 2 thefe 78 OF STIMULUS AND EXERTION. SECT. XII. 2. thefe is called by Dr. Brown, in his Elements of Medicine, direct debility, and the latter indirect de- bility. The coincidence of fome parts of this work with correfpondent deductions in the Brunonian Elementa Medicinee, a work (with fome exceptions) of great genius, muft be confidered as confirmati- ons of the truth of the theory, as they were pro- bably arrived at by different trains of reafoning. Thus in thofe who have been expofed to cold and hunger there is a deficiency of ftimulus. While in nervous fever there is a deficiency of fenforial power. And in habitual drunkards, in a morning before their ufual potation, there is a deficiency both of ftimulus and of fenforial power. While, on the other hand, in the beginning of intoxication there is an excefs of ftimulus ; in the hot-ach, after the hands have been immerfed in mow, there is a redundancy of fenforial power ; and in inflamma- tory difeafes with arterial ftrength, there is an ex- cefs of both. Hence if the fenforial power be leffened, while the quantity of ftimulus remains the fame as in nervous fever, the frequency of repetition of the arterial contractions may continue, but their force in refpect to removing obftacles, as in promoting the circulation of the blood, or the velocity of each contraction, will be diminifhed, that is, the animal ftrength will be leffened. And fecondly, if the quantity of fenforial power be leffened, and the fti- mulus be increafed to a certain degree, as in giving opium in nervous fevers, the arterial contractions may be performed more frequently than natural, yet with lefs ftrength. And thirdly, if the fenforial power continues the fame in refpect to quantity, and the ftimulus be fomewhat diminifhed, as in going into a darkifh room, or into a coldifli bath, fuppofe of about eighty degrees of heat, as Buxton-bath, a tempo- rary SICT. XII. 2. OF STIMULUS AND EXERTION. 79 rary weaknefs of the affefted fibres is induced, till an accumulation of fenibrial power gradually fuc- ceeds, and counterbalances the deficiency of ftimu- lus, and then the bath ceafes to feel cold, and the room ceafes to appear dark ; becaufe the fibres of the fubcutaneous vefiels, or of the organs, of fenfe, act with their ufual energy. A fet of mufcular fibres may thus be ftimulated into violent exertion, that is, they may act fre- quently, and with their whole fenforial power, but may ne vert helefs not aft ftrongly ; becaufe the quan- tity of their fenforial power was originally fmall, or was previoufly exhaufted. Hence a ftimulus may be great, and the irritation in confequence act with its full force, as in the hot paroxyfms of ner- vous fever ; but >f the fenforial power, termed irri- tation, be fmall in quantity, the force of the fibrous contractions, and the times of their continuance in their contracted ftate, will be proportionally fmall. In the fame manner in the hot paroxyfm of- putrid fevers, which are (hewn in Se<5t. XXXI-II. to be inflammatory fevers with arterial debility, the fenforial power termed fen fat ion is exerted with great activity, yet the fibrous contractions, which produce the circulation of the blood, are perform- ed without ftrength, becaufe the quantity of fenfo- rial power then refiding in that part of the fyftem is fmall. Thus in irritative fever with arterial ftrength, that is, with excefs of fpirit of ani mation, the quan- tity of exertion during the hot part of the paroxyfrn is to be eftirnated from the quantity of ftimulus, and the quantity of fenforial power. While in fen- fitive (or inflammatory) fever with arterial ftrength, that is, with excefs of fpirit of animation, the violent and forcible actions of the vafcular fyftem during the hot part of the paroxyfm are induced by the exertions of two fenibrial powers, which are excited So OF STIMULUS AND EXERTION. SECT. XII. 2 excited by two kinds of fiimulus. Thefe are the fenforial power of irritation excited by the ilimulus of bodies external to the moving fibres, and the fenforial power of fenfation excited by the pain in confequence of the increafed contractions of thofe moving fibres. And in infane people in fome cafes the force of their mufcular actions will be in proportion to the quantity of fenforial power, which they poilefs, and the quantity of the fiimulus of deiire or averfion, which excites their volition into action. At the fame time in other cafes the famulus of pain or pleafure, and the fiimulus of external bodies, may excite into action the fenforial powers of fenfation and irritation, arid thus add greater force to their mufcular actions. 2. The application of the ilimulus, whether that fiimulus be fome quality of external bodies, or pleafure or pain, or defire or averfion, or a link of affociation, excites the correfpondent fenforial power into action, and this cauies the contraction of the fibre. On the contraction of the fibre a part of the fpirit of animation becomes expended, and the fibre ceafes to contract, though the ilimulus conti- nues to be applied ; till in a certain time the fibre having received a fupply of fenforial power is ready to contract again, if the ilimulus continues to be applied. If the ilimulus on the contrary be with- drawn, the fame quantity of quiefcent fenforial power becomes refident in the fibre as before its contraction ; as appears from the readinefs for ac- tion of the large locomotive mufcles of the body in a (hort time after common exertion. But in thofe mufcuiar fibres, which are fubject to conilant itimulus, as the arteries, glands, and capillary veflels, another phenomenon occurs, if their accuftomed ilimulus be withdrawn ; which is, that the fenforial power becomes accumulated in the contractile SECT. XII. 2. OF STIMULUS AND EXERTION. *i contractile fibres, owing to the want of its being perpetually expended, or carried away, by their ufual unremitted contractions. And on this ac- count thofe inufcular fibres become afterwards ex- citable into their natural actions by a much weaker ftimulus ; or into unnatural violence of action by their accuftomed ftimulus, as is feen in the hot fits of intermittent fevers, which are in confequence of the previous cold ones. Thus the minute veifels of the fkin are conftantly flimulated by the fluid mat- ter of heat ; if the quantity of this iiimulus of heat be a while diminished, as in covering the hands with fnow, the vefleis ceafe to act, as appears from the palenefs of the fkin ; if this cold application of fnow be continued but a mort time, the fenfo- rial power, which had habitually been fupplied to the fibres, becomes now accumulated in them, ow- ing to the want of its being expended by their ac- cuftomed contractions. And thence a lei's ftimulus of heat will now excite them into violent contrac- tions. If the quiefcence of fibres, which had previoufly been fubjecl: to perpetual ftimulus, continues a lon- ger time ; or their accuftomed ftimulus be more completely withdrawn ; the accumulation of fen- forial power becomes fiill greater* as in thofe ex- pofed to cold and hunger ; pain is produced, and the organ gradually dies from the chemical changes, which take place in it ; or it is at a great diitance of time reftored to action by ftimulus applied with great caution in frnail quantity, as happens to fome larger animals and to many infects, which during the winter months lie benumbed with cold, and are faid to fleep, and to perfons apparently drowned, or apparently frozen to death. Snails have been faid to revive by throwing them into water after having been many years fhut up in the cabinets of the curious 5 82 OF STIMULUS AND EXERTION. SECT. XII. 2, curious; and eggs and feeds in general are reHored to life after many months of torpor by the ftimu- lus of warmth and moiiture. The inflammation of fchirrous tumours, which have long exifted in a (late of inaction, is a procefs of this kind; as well as the fenfibility acquired by inflamed tendons and bone.s, which had at their formation a fimilar fenfibility, which had fo long lain dormant in their uninflamed ftate. 3. If after long quiefccnce from defect of ftimu- lus the fibres, which had previoufly been habitu- ated to perpetual ftimulus, are again expofed to but their ufual quantity of it ; as in thofe who have fuffered the extremes of cold or hunger ; a violent exertion of the affected organ commences, owing, as above explained, to the great accumulation of fenforial power. This violent exertion not only diminiihes the accumulated fpirit of animation, but at the fame time induces pleafure or pain into the fyftem, which, whether it be fucceeded by inflam- mation or not, becomes an additional ftimulus, and acting along with the former one, produces ftill greater exertions ; and thus reduces the fenforial power in the contracting fibres beneath its natural quantity. When the fpirit of animation is thus exhaufted by ufelefs exertions, the organ becomes torpid or unexcitable into action, and a fecond fit of quief- cence fucceeds that of abundant activity. During this fecond fit of quiefcencc the fenforial power be- comes again accumulated, and another fit of exer- tion follows in train. Thefe vicitlitudes of exer- tion and inertion of the arterial fyftem conftitute the paroxyfms of remittent fevers ; or intermittent ones, when there is an interval of the natural ac- tion of the arteries between the exacerbations. In thefe paroxyfms of fevers, which confift of the libration of the arterial fyftem between the ex- tremes . XII. 3. OF STIMULUS AND EXERTION. 83 tremes of exertion and quiefcence, either the fits become lefs and lefs violent from the contractile fibres becoming lefs excitable to the ftimulus by ha- bit, that is, by becoming accuftomed to it, as ex- plained below XII. 3. i. or the whole fenforial power becomes exhaufted, and the arteries ceafe to beat, and the patient dies in the cold part of the paroxyfm. Or fecondly, fo much pain is intro- duced into the fyftem by the violent contractions of the fibres, that inflammation arifes, which pre- vents future cold fits by expending a part of the fenforial power in the exteniion of old vefiels or the production of new ones; and thus preventing the too great accumulation or exertion of it in other parts of the fyftem ; or which by the great increafe of ftimulus excites into great action the whole glan- dular fyilem as well as the arterial, and thence a greater quantity of fenforial power is produced in the brain, and thus its exhauftion in any peculiar part of the fyftem ceafes to be affected. 4. Or thirdly, in confequence of the painful or pleafurable fenfation above mentioned, defire and averfion are introduced, and inordinate volition fucceeds ; which by its own exertions expends fo much of the fpirit of animation, that the two other fenforial faculties, or irritation and fen far ion, act fo much more feebly ; that the paroxyfms of fever, or that libration between the extremes of exert -'on and inactivity of the arterial fyitem, gradually fub- fides. On this account a temporary infanity is a favourable fign in fevers, as I have had fbme op. portunities of obferving. III. Of repeated Stimulus. i. When a ftimulus is repeated more frequently than the expenditure of fenforial power can be re- newed in the acting organ, the effect of ihe ftimu- lus «4 OF STIMULUS AND EXERTION. SECT. XII. 3. lus becomes gradually diminimed. Thus if two grains of opium be fwallowed by a perfon unufed to ib ftrong a ftimulus, all the vafcular fyftems in the body act with greater energy, ali the fecretions and the abforption from thofe fecreted fluids are increafed in quantity ; and pleafure or plain are in- troduced into the fyftem, which adds an additional ftimulus to that already to6 great. After fome Jiours the fenforial power becomes diminifhed in quantity, expended by the great activity of, the iyftern ; and thence, when the ftimulus of the opium is withdrawn, the fibres will not obey their ufual degree of natural (limulus, and a confequent torpor or quiefcence fucceeds, as is experienced by drunkards, who on the day after a great excefs of fpirituous potation feel indigeftion, head-ach, and general debility. In this fit of torpor or quiefcence of a part or of the whole of the fyftem, an accumulation of the fen- forial power in the affected fibres is formed, and occaiions a fecond paroxyfm of exertion by the ap- plication only of the natural ftimulus, and thus a libration of the fenforial exertion between one ex- cefs and the other continues for two or three days, where the ftimulus was violent in degree ; and for weeks in fome fevers, from the ftimulus of conta- gious matter. ^'< But if a fecond dofe of opium be exhibited be- fore the fibres have regained their natural quantity of fenforial power, its effect will be much lefs than the former, becaufe the fpirit of animation or fen- forial power is in part exhaufted by the previous excefs of exertion. Hence all medicines repeated too frequently gradually lofe their effect, as opium and wine. Many things of difagreeable tafte at firft ceafe to be difagreeable by frequent repetition, as- tobacco ; grief and pain gradually diminifh, and at SECT. XII. 3. OF STIMULUS AND EXERTION. 85 at length ceafe altogether, and hence life itfelf be- comes tolerable. Be (ides the temporary diminution of the fpirit of animation or fen ferial power, which is naturally ftationary or refident in every living f-bre, by a ilngle exhibition of a powerful ftimulus, the contrac- tile fibres themfeives, by the perpetual application of a new quantity of ftimulus, before they have re- gained their natural quantity of fenforial power, appear to fuffer in their capability of receiving fo much as the natural quantity of (enibrial power ; and hence a permanent deficiency of fpirit of ani- mation take* place, however long the ftimulus may have been withdrawn. On this caufe depends the permanent debility of thofe, who have been addicled to intoxication, the general weaknefs of old age, and the natural debility or inirritability of thofe, who have pale {kins and large pupils of their eyes. There is a curious phenomenon belongs to this place, which has always appeared difficult of folu- tion j and that is, that opium or aloes may be ex* hibited in fmall dofes at firft, and gradually in- creafed to very large ones without producing ftu- por or diarrhoea. In this cafe, though the opium and aloes are given in fuch fmall doles as not to produce intoxicatioij or cathariis, yet they are ex* hibited in quantities fuilicient in fame degree to exhauft the fenforial power, and hence a ftronger and a ilronger dofe is required ; otherwife- the me- dicine would foon ceafe to act at all. On the contrary, if the opium or aloes be exhi- bited in a large dofe at firft, fo as to produce in- toxication or diarrhoea; after a few repetitions the quantity of either of them may be diminifhed, and they will ftill produce this effect, For the more powerful ftimulus dhTevers the progreffive catena- tions of animal motions, defcribed in Sect XVjj. and 86 OF STIMULUS AND EXERTION. SECT.' X II. 3. and introduces a new link between them ; whence every repetition ftrengthens this new affociation or catenation, and the ilimulus may be gradually de- creafed, or be nearly withdrawn, and yet the ef- fect mail c ntinue ; becaufe the ienforial power of aifociation or catenation being united with the fti- inulus, increafes in energy with every repetition of the catenated circle ; and it is by thefe means that all the irritative affociations of motions are originally produced. 2. When a ftimulus is repeated at fuch diftant intervals of time, that the natural quantity of fen- ibrial power becomes completely reftored in the acting fibres, it will acl with the fame energy as when firft applied. Hence thofe who have lately accuftomed ihemfelves to large dofes of opium by beginning with fmall ones, and gradually increaf- ingthem, and repeating them frequently, as men- tioned in the preceding paragraph ; if they inter- mit the ufe of it for a few days only, mult begin again with as fmall dofes as they took at firft, other- wife they will experience the inconveniences of in- toxication. On this circumftance depend the conftant un- failing effects of the various kinds of flimulus, which excite into aclion all the vafcular fyilems in the body ; the arterial, venous, abforbent, and glandular veflcls, are brought into perpetual un- wearied aftion by the fluids, which are adapted to IHmuIate them ; but thefe have the fenforial power of affociation added to that of irritation, and even in foine degree that of fenfation, and even of voli- tion, as will be fpoken of in their places ; and life itfelf is thus carried on by the production of fenfo- rial power being equal to its wafte or expenditure in the perpetual movement of the vafcular organi- zation. 7. When SECT. XII. 3. OF STIMULUS AND EXERTION. 87 3. When a ftimulus is repeated at uniform in- tervals of time with fuch diftances between them, that the expenditure of fenforial power in the act- ing fibres becomes completely renewed, the effect is produced with greater facility or energy. For the fenforial power of allbciation is combined with the fenforial power of irritation, or, in common lan- guage, the acquired habit aflifts the power of the ilimulus. This circumftance not only obtains in the annual and diurnal catenations of animal motions explain- ed in Sect. XXXVI. but in every lefs circle of ac- tions or ideas, as in the burthen of a fong, or the iterations of a dance ; and conftitutes the pleafure we receive from repetition and imitation ; as treat- ed of in Sett. XXII. 2. 4. When a ftimulus has been many times repeat- ed at uniform intervals, fo as to produce the com- plete action of the organ, it may then be gradual- ly diminifhed, or totally withdrawn, and the ac- tion of the organ will continue. For the fenforial power of affociation becomes united with that of irritation, and by frequent repetition becomes at length of fufficient energy to carry on the new link in the circle of actions, without the irritation which at firft introduced it. Hence, when the bark is given at dated inter- vals for the cure of intermittent fevers, if fixty grains of it be given every three hours for the twenty-four hours preceding the expected pa- roxyfm, fo as to ftimulate the defective part of the fyftem into action, and by that means to prevent the torpor or quiefcence of the fibres, which con- ititutes the cold fit ; much lefs than half the quan- tity, given before the time at which another pa- roxyfm of quiefcence would have taken place, will be fufficient to prevent it ; becaufe now the fenfo- rial power, termed affociation, acts in a twofold manner, 88 OF STIMULUS AND EXERTION. SECT. XII. 3- manner. Firfl, in refpect to the period of the ca- tenation in which the cold fit was produced, which is now diflevered by the ftronger ftimulus of the firft dofes of the bark ; and, fecondly, becaufe each dofe of* bark being repeated at periodical times, has its effect increafed by the fenibrial faculty of affo- ciation being combined with that of irritation. Now, when fixty grains of Peruvian bark are taken twice a day, fuppofe at ten. o'clock and at fix, for a fortnight, the irritation excited by this additional ttimulus becomes a part of the diurnal circle -of actions, and will at length carry on the increafed action of the fyftem without the afliftance of the flimulus of the bark. On this theory the bitter medicines, chalybeates, and opiates in ap- propriated dofes, exhibited for a fortnight, give permanent ftrength to pale feeble children, and other weak conftitutions. 5. When a defect of ftimulus, as of heat, recurs at certain diurnal intervals, which induces fome torpor or quiefcence of a part of the fyftem, the diurnal catenation of actions becomes difordered, and a new aflbciation with this link of torpid ac- tion is formed \ on the next period the quantity of quiefcence will be increafed, fuppofe the fame defect of ftimulus to recur, becaufe now the new aflbciation confpires with the defective irritation in introducing the torpid action of this part of the diurnal catenation. In this manner many fever- fits commence, where the patient is for fome days indifpoied at certain hours, before the cold pa- roxyfm of fever is completely formed. See Sect. XVII. 3. 3. on Catenation of Animal Motions. 6. If a ftimulus, which at firft excited the affect- ed organ into fo great exertion as to produce fen- fation, be continued for a certain time, it will ceafe to produce fenfation both then and when repeated, though SECT. XII. 3. OF STIMULUS AND EXEP TION. S9 though the irritative motions in confcquence of it may continue or be re-excited. Many catenations of irritative motions were at firil fucceeded by fenfation, as the apparent motions of objects when we walk pad them, and probably the vital motions themfelves in the early ftate of our exiftence. But as thofe fenfations were fol- lowed by no movements of the fyftem in confe- quence of them, they gradually ceafed to be pro- duced, not being joined to any fucceeding link of catenation. Hence contagious matter, which has for fome weeks ilimulated the fyftem into great and permanent fenfation, ceafes afterwards to produce general fenfation or inflammation, though it may ilill induce topical irritations. See Sect. XXXIII. 2. 8. XIX. 10. Our abforbent fyitem then feems to receive thofe contagious matters, which it has before experi- enced, in the fame manner as it imbibes commoa moifture or other fluids ; that is, without being thrown into fo violent action as to produce fenfa- tion ; the confequence of which is an increafe of daily energy or activity, till inflammation and its confequences fucceed. 7. If a ftimulus excites an organ into fuch vio- lent contractions as to produce fenfation, the mo- tions of which organ had not ufually produced fen- fation, this new fenforial power, added to the ir- ritation occafioned by the ftimulus, increafes the activity of the organ. And if this activity be ca- tenated with the diurnal circle of actions, an in- creafing inflammation is produced ; as in the even- ing paroxyfms of fmall-pox, and other fevers with inflammation. And hence fchirrous tumours, ten- dons and membranes, and probably the arteries themfelves become inflamed, when they are itrong, ly Simulated. IV. Of 90 OF STIMULUS AND EXERTION. SECT. XII. 4. IV. Of Stimulus greater than natural. i. A quantity of ftimulus greater than natural, producing an increafed exertion of fenforial power, whether that exertion be in the mode of irritation, fenfation, volition, or affociation, diminiflies the general quantity of it. This fact is obfervable in the progrefs of intoxication, as the increafed quan- tity or energy of the irritative motions, owing to the ftimulus of vinous fpirit, introduces much plea- furable fenfation into the fyftem, and much exertion of mufcular or fenfual motions in confequence of this increafed fenfation ; the voluntary motions, and even the aflbciate ones, become much impaired or diminimed ; and delirium and Daggering fucceed. See Seel. XXI. on Drunkennefs. And hence the great proftration of the ftrength of the locomotive mufcles in fome fevers, is owing to the exhauftion of fenforial power by the increafed aftion of the arterial fyftem. In like manner a ftimulus greater than natural, applied to a part of the fyftem, increafes the exer- tion of fenforial power in that part, and diminifhes it in fome other part. As in the commencement of fcarlet fever, it is ufual to fee great rednefs and heat on the faces and breafts of children, while at the fame time their feet are colder than natural ; partial heats are obfervable in other fevers with de- bility, and are generally attended with torpor or quiefcence of fome other part of the fyftem. But thefe partial exertions of fenforial power are fome- times attended with increafed partial exertions in other parts of the fyftem, which fympathzie with them, as the flufhing of the face after a full meal. Both thefe therefore are to be afcribed to fympa- thetic aflbciations, explained in Seel, XXXV. and not SECT. XII. 4. OF STIMULUS AND EXERTION. 9? not to general exauftion or accumulation of fenfo- rial power. 2 A quantity of (limul us greater than natural, producing an increafed exertion of fenforial power in any particular organ, diminifhes the quantity of it in that organ. This appears from the con- tractions of animal fibres being not fo eafily excit- ed by a lefs itimulus after the organ has been fub- jecled to a greater. Thus after looking at any luminous object of a fmall fize, as at the fetting fun, for a fhort time, fo as not much to fatigue the eye, this part of the retina becomes lefs fenfible to fmal- ler quantities of light ; hence when the eyes are turned on other lefs luminous parts of the Iky, a dark fpot is feen refembling the fhape of the fun, or other luminous object which we laft behold. See Seel. XL. No. 2. Thus we are fome time before we can diftinguifh objects in an obfcure room after coming from bright day-light, though the iris prefently contracts itfelf. We are not able to hear weak founds after loud ones. And the ftomachs of thofe who have been much habituated to the ftronger flimulus of fermented or fpirituous liquors, are not excited into due action by weaker ones, 3. A quantity of iiimulus fomething greater than the laft mentioned, or longer continued, induces the organ into fpafmodic action, which ceafes and recurs alternately. Thus on looking for a time on the fetting fun, fo as not greatly to fatigue the fight, a yellow fpectrum is feen when the eyes are clofed and covered, which continues for a time, and then difappears and recurs repeatedly before it entirely vaniihes. See Sect. XL. No. 5. Thus the action of vomiting ceafes and is renewed by intervals, although the emetic drug is thrown up with the firft effort. A tenefmus continues by intervals fome time after the exclufion of acrid H excrement ; 9* OF STIMULUS AND EXERTION. SECT. XII. excrement ; and the pulfations of the heart of a viper are faid to continue fome time after it is cleared from its blood. In thefe cafes the violent contractions of the fibres produce pain according to law 4 ; and this pain conftitutes an additional kind or quantity of ex- citement, which again induces the fibres into con- traction, and which painful excitement is again renewed, and again induces contractions of the fibres with gradually diminifhing effect. 4. A quantity of flimulus greater than the laft mentioned, or longer continued, induces the an- tagonift mufcles into fpafmodic action. This is beautifully iiluftrated by the ocular fpectra de- fcribed in Sect. XL. No. 6. to which the reader is referred. From thofe experiments there is rea- fon to conclude that the fatigued part of the re- tina throws itfelf into a contrary mode of action like ofcitation or pandiculation, as foon as the fti- mulus, which has fatigued it, is withdrawn ; but that it ftill remains liable to be excited into action by any other colours except the colour with which it has been fatigued. Thus the yawning and ftretch- ing the limbs after a continued action or attitude feems occalioned by the antagonift mufcles being ftimulated by their extenfion during the contrac- tions of thofe in action, or in the fituation in which that action laft left them. 5. A quantity of ftimulus greater than the laft, or longer continued, induces variety of convulfions or fixed fpafms either of the affected organ or of the moving fibres in the other parts of the body. In refpect to the fpectra in the eye, this is well ii- luftrated in No. 7. and 3, of Sect XL. Epileptic convulfions, as theemprofthotonos and opifthotonos, with the cramp of the calf of the leg, locked jaw, and other cataleptic fits, appear to originate from pain, as fome of thefe patients fcream aloud be- fore SECT. XII. 4. OF STIMULUS AND EXERTION. 93 fore the convulfion takes place; which feems at firft to be an effort to relieve painful fenfation, and afterwards an effort to prevent it. In thefe cafes the violent contractions of the fibres produce fo much pain, as to conftitute a per- petual excitement ; and that in fo great a degree as to allow but fmall intervals* of relaxation of the contracting fibres as in convulfions, or no inter- vals at all as in fixed fpafms. 6. A quantity of (limulus greater than the laft, or longer continued, produces a paralyfis of the organ. In many cafes this paralyfis is only a tem- porary effect, as on looking long on a fmall area of bright red (ilk placed on a meet of white paper on the floor in a (Iron g light, the red filk gradually becomes paler, and at length difappears ; which evinces that a part of the retina, by being violently excited, becomes for a time unaffected by the'fti- mulus of that colour. Thus cathartic medicines, opiates, poifons, contagious matter, ceafe to in- fluence our fyftem after it has been habituated to the ufe of them, except by the exhibition of in- creafed quantities of them ; our fibres not only be- come unaffected by ftimuli, by which they have previoufly been violently irritated, as by the mat- ter of the fm all-pox or mealies ; but they alfo be- come unaffected by fenfation, where the violent exertions, which difobled them, were in confe- quence of too great quantity of fenfation. And laftly, the fibres, which become difobedient to vo- lition, are probably difabled by their too violent exertions in confequence of too great a quantity of volition. After every exertion of our fibres a temporary paralyfis fucceeds, whence the intervals of all muf- cular contractions, as mentioned in No. 3 and 4 of this Section ; the immediate caufe of thefe more permanent kinds of paralyfis is probably owing in H 2 the 94 OF STIMULUS AND EXERTION. SECT. XII 5. the fame manner to the too great exhauftion of the fpirit of animation in the affected part ; fo that a ftronger ftimulus is required, or one of a different kind from that, which occafioned thofe too violent contractions, to again excite the affected organ into activity ; and if a ftronger ftimulus could be applied, it muft again induce paralyfis. For theie powerful ftimuli excite pain at the fame time, that they produce irritation ; and this pain not only excites fibrous motions by its ftimulus, but it alfo produces volition ; and thus all thefe ftimuli acting at the fame time, and fometimes with the addition of their aflbciations, produce fo great exertion as to expend the whole of tire fenforial power in the affected fibres. V. Of Stimulus lefs than natural. i. A quantity of ftimulus lefs than natural, pro- ducing a decreafed exertion of fenforial power, oc- cafions an accumulation of the general quantity of it. This circumftance is obfervable in the hemi- plagia, in which the patients are perpetually moving the mufcles, which are unaffected. On this ac- count we awake with greater vigour after fleep, becaufe during fo many hours, the great ufual ex- penditure of fenforial power in the performance of voluntary actions, and in the exertions of our or- gans of fenfe, in confequence of the irritations oc- cafioned by external objects, had been fufpended, and a confequent accumulation had taken place. In like manner the exertion of the fenforial power lefs than natural in one part of the fyftem, isliabls to produce an increafe of the exertion of it in fome other part. Thus by the action of vomit- ing, in which the natural exertions of the motions of the ftomach are deiiroyed or dirmniihed, an in- creafed SECT. XII. 5. OF STIMULUS AND EXERTION. 95- creafed abforption of the pulmonary and cellular lymphatics is produced, as is known by the in- creafed abforption of the fluid depofired in them in dropfical cafes. But thefe partial quiefcences of fenibrial power are alfo fometimes attended with other partial quiefcences, which fympathife with them, as cold and pale extremities from hunger. Thefe therefore are to be afcribed to the affociations of fympathy explained in Sect, XXXV. and not to the general accumulation of fenforiai power. 2. A quantity of Rimulus lefs than natural, ap- plied to fibres previoufly accuftomed to perpetual ftimuius, is iucceeded by accumulation of fenforiai power in the affected organ. The truth of this proportion is evinced., becaufe a ftimuius lefs than natural, if it be fomewhat greater than that above mentioned, will excite the organ fo circumftanced into violent activity. Thus on a frofty day with wind, t^e face of a perfon expofed to the wind is at firft pale and fhrunk ; but on turning the face from the wind, it becomes foon of a glow with waimth and flufliing. The glow of the fkin in emerging from the cold-bath is owing to the fame caufe. It does not appear, that an accumulation of fen- foriai power above the natural quantity is acquired by thofe mufcles, which are not fubject to perpe- tual ftimuius, as the locomotive mufcles : thefe, after the greateft fatigue, only acquire by reft their ufual aptitude to motion ; whereas the vafcular fyftem, as the heart and arteries, after a fliort qui- efcence, are thrown into violent action by their na- tural quantity of flimulus. Neverthelefs by this accumulation of fenforiai power during the application of decreafed ftimuius, and by the exhauftion of it during the action of in- creafed ftimuius, it is wifely provided, that the ac- tions of the vafcular mufcles and organs of fenfe are 96 OF STIMULUS AND EXERTION. SECT. XII. 5. are not much deranged by fmall variations of fti- mulus ; as the quantity of fenforial power becomes in fome meafure inversely as the quantity of fti- mulus. 3. A quantity of ftimulus lefs than that men- tioned above, and, continued for fome time, in- duces pain in the affected organ, as the pain of cold in the hands, when they are immerfed in fnow, is owing to a deficiency of the ftimulation of heat. Hunger is a pain from the deficiency of the ftimula- tion of food. Pain in the back at the commence- ment of ague-fits, and the head-achs which attend feeble people, are pains from defect of ftimulus, and are hence relieved by opium, eflential oils, fpirit of wine. As the pains, which originate from defect of ftimulus, only occur in thofe parts of the fyftem, which have been previoufly fubjected to perpetual ftimulus ; and as an accumulation of fenforial power is produced in the quiefcent organ along with the pain, as in cold or hunger, there is reafon to believe, that the pain is owing to the accumula- tion of fenforial power, For, in the locomotive mufcles, in the retina of the eye, and other organs of fenfes, no pain occurs from the abfence of fti- mulus, nor any great accumulation of fenforial power beyond their natural quantity, fince thefe organs have not been ufed to a perpetual fupply of it. There is indeed a greater accumulation occurs in the organ of vifion after its quiefcence, becaufe it is fubject to more conftant ftimulus. 4. A certain quantity of ftimulus lefs than natu- ral induces the moving organ into feebler and more frequent contractions, as mentioned in No. I. 4. of this Section. For each contraction moving through a lefs fpace, or with lefs force, that is, with lefs expenditure of the fpirit of animation, is fooner relaxed, and the fpirit of animation derived SECT. XII. 5. OF STIMULUS AND EXERTION. 97 derived at each interval into the acting fibres being lefs, thefe intervals likewife become fhorter. Hence the tremours of the hands of people accuf- tomed to vinous fpirit, till they take their ufual flimulus ; hence the quick pulfe in fevers attended with ftrength ; in the latter the pulfe feldom beats above 120 times in a minute, in the former it frequently exceeds 140. It muft be obferved, that in this and the two following articles the decreafed action of the fyf- tem is probably more frequently occafioned by deficiency in the quantity of fenforial power, than in the quantity of ftimulus. Thus thofe feeble conftitutions which have large pupils of their eyes, and all who labour under nervous fevers, feem to owe their want of natural quantity of activity in the fyftem to the deficiency of fenforial power ; iince, as far as can be feen, they frequently poflefs the natural quantity of flimulus. 5. A certain quantity of ft imulus, lefs than that above mentioned, inverts the order of fucceffive fibrous contractions ; as in vomiting the vermi- cular motions of the ftomach and duodenum are inverted, and their contents ejected, which is probably owing to the exhauftion of the fpirit of animation in the acting mufcles by a previous excefllve flimulus, as by the root of ipecacuanha, and the confequent defect of fenforial power. The fame retrograde motions affect the whole inteftinal canal in ileus ; and the cefophagus in globus hyf- tericus. See this further explained in Sect. XXIX. No. ii. on Retrograde Motions, I muft obferve, alfo, that fomething fimilar hap- pens in the production of our ideas, or fenfual motions, when they are too weakly excited 5 when any one is thinking intenfely about one thing, and carelefsly converfing about another, he is liable to ufe the word of a contrary meaning to that 98 OF STIMULUS AND EXERTION. SECT. XII. 6. that which he defigned, as cold weather for hot weather, fummer for winter. 6. A certain quantity of (limulus, lefs than that above mentioned, is/fucceeded by paralyfis, firft of the voluntary and feniitive motions, and after- wards of thofe of irritation and of affociation, which conilitutes death. Vf. Cure of increafed Exertion. i. The cure, which nature has provided for the increafed exertion of any part of the fyftem, con- lifts in the confequent expenditure of the fenforial power. But as a greater torpor follows this ex- hauftion of fenforial power, as explained in the. next paragraph, and a greater exertion fucceeds this torpor, the conftitution frequently finks under thefe increafing librations -between exertion and quiefcence ; till at length complete quiefcence, that is, death, clofes the fcene. For, during the great exertion of the fyftem in the hot fit of fever, an increafe of ftimulus is pro- duced from the greater momentum of the blood, the greater diftention of the heart and arteries, and the increafed production of heat, by the violent aclions of the fyftem occafioned by this augmenta- tion of ftimulus, the fenforial power becomes di- minifhed in a few hours much beneath its natural quantity, the veflels at length ceafe to obey even thefe great degrees of ftimulus, as fliewn in Sect. XL. 9. i. and a torpor of the whole or of a part of the fyftem enfues. Now as this fecond cold fit commences with a greater deficiency of fenforial power, it is alfo at- tended with a greater deficiency of ftimulus than in the preceding cold fit, that is, with lefs momentum of blood, lefs diftention of the heart. On this ac- count the fecond cold fit becomes more violent and of SECT. XII. 6. OF STIMULUS AND EXERTION. 99 of longer duration than the firft ; and as a greater accumulation of fenforial power muft be produced before the fyftern of veffels will again obey the di- minifhcd ftimulus, it follows, that the fecond hot fit of fever will be more violent than the former one. And that unlefs fome other caufes counter- act either the violent exertions in the hot fit, or the great torpor in the cold fit, life will at length be extinguifhed by the expenditure of the whole of the ienforial power. And from hence it appears, that the true means of curing fevers muft be fuch as decreafe the aclion of the fyftem in the hot fit, and increafe it in the cold fit ; that is, fuch as pre- vent the too great diminution of fenforial power in the hot fit, and the too great accumulation of it in the cold one. 2. Where the exertion of the fenforial powers is much increafed, as in the hot fits of fever or in- flammation, the following are the ufual means of relieving it. Decreafe the irritations by blood- letting, and other evacuations ; by cold water taken into the ftomach, or injected as an enema, or ufed externally ; by cold air breathed into the lungs, and diflufed over the Ikin ; with food of lefs ftimu- lus than the patient has been accuftomed to. 3. As a cold fit, or paroxyfm of inactivity of fome parts of the fyftem, generally precedes the hot fit, or paroxyfm of exertion, by which the fenfo- rial power becomes accumulated, this cold parox- yfm fhould be prevented by ftimulant medicines and diet, as wine, opium, bark, warmth, cheer- fulnefs, anger, furprife. 4. Excite intD greater action fome other part of the fyftem, by which means the fpirit of animation may be in part expended, and thence the inordi- nate actions of the difeafed part may be leffened. Hence when a part of the Ikin acts violently, as of the face in the eruption of the fmall pox, if the feet #t>o OF STIMULUS AND EXERTION. SECT. XII. 7. feet be cold they fhould be covered. Hence the ufe of a blilter applied near a topical inflammation. Hence opium and warm bath relieve pains both from excefs and defect of ftimulus. 5. Firft increafe the general ftimulation above its natural quantity, which may in fome degree ex- hauft the fpirit of animation, and then decreafe the ftimulation beneath its natural quantity. Hence after iudorific medicines and warm air, the appli- cation of refrigerants may have greater effect, if they could be adminiftered without danger of pro- ducing too great torpor of fome part of the fyftem ; as frequently happens to people in health from coming out of a warm room into the cold air, by which a topical inflammation in confequence of torpor of the mucous membrane of the noftril is produced, and is termed a cold in the head. VII. Cure of decreqfed Exertion. ^d sqonjniru ia? afe'fOsaCl ; , . * i. WHERE the exertion of the fenforial powers is much decreafed, as in the cold fits of fever, a gradual accumulation of the fpirit of animation takes place ; as occurs in all cafes where inactivity or torpor of a part of the fyftem exifts ; this accu- mulation of fenforial power increafes, till ftimuli lefs than natural are fufficient to throw it into action, then the cold fit ceafes ; and from the ac- tion of the natural ftimuli a hot one fucceeds with increafed activity of the whole fyftem. So in fainting fits, or fyncope, there is a tempo- rary deficiency of fenforial exertion, and a confe- quent quiefcence of a great part of the fyftem. This quiefcence continues, till the fenforial power be- comes again accumulated in the torpid organs; and then the ufual diurnal ftimuli excite the revi- vifcent parts again into action ; but as this kind of quiefcence continues but a fhort time compared to SECT. XIT. 7. OF STIMULUS AND EXERTION. 101 to the cold paroxyfm of an ague, and lefs affects the circulatory fyftem, a lefs fuperabundancy of exertion fucceeds in the organs previoufly torpid, and a lefs excefs of arterial activity. See Sect. XXXIV. i. 6. 2. In the difeafes occafioned by a defect of fenfo- rial exertion, as in cold fits of ague, hyfteric com- plaint, and nervous fever, the following means are t hole commonly ufed. i. Increafe the ftimulatioii above its natural quantity for fome weeks, till a new habit of more energetic contraction of the fibres is eftablifhed. This is to be done by wine, opium, bark, fteel, given at exact periods, and in appropriate quantities ; for if thefe medicines be given in fuch quantity, as to induce the lead de- gree of intoxication, a debility fucceeds from the ufelefs exhauftion of fpirit of animation in confe- quence of too great exertion of the mufcles or or- gans of fenfe. To thefe irritative ftimuli mould be added the fenfitive ones of cheerful ideas, hope, affection. 3. Change the kinds of ftimulus. The habits acquired by the conftitution depend on fuch nice circumftances, that when one kind of ftimulus ceafes to excite the fenforial power into the quan- tity of exertion neceffary to health, it is often fuf- ficient to change the ftimulus for another appar- ently fimilar in quantity and quality. Thus when wine ceafes to ftimulate the conftitution, opium in appropriate dofes fupplies the defect ; and the con- trary. This is alfo obferved in the effects of ca- thartic medicines, when one lofes its power, ano- ther, apparently lefs efficacious, will fucceed. Hence a change of diet, drink, and ftimulating medi- cines, is often advantageous in difeafes of debi- lity. 4. Stimulate the organs, whofe motions are af- fociated with the torpid parts of the fyftem. The actions 102 OF STIMULUS AND EXERTION. SECT. XII. 7, actions of the minute veflels of the various parts of the external Ikin are not only aflbciated with each other, but are ftrongly aflbciated with thofe of fome of the internal membranes, and particu- larly of the ftomach. Hence when the exertion of the ftomach is lefs than natural, and indigeftion and heart-burn fucceed, nothing fo certainly re- moves thefe fymptoms as the ftimulus of a blifter on the back. The coldnefs of the extremities, as of the nofe, ears, or fingers, are hence the beft in- dication for the fuccefsful application of blifters. 5, Decreafe the ftimulus for a time. By leflen- ing the quantity of heat for a minute or two by going into the cold bath, a great accumulation of ienfoiial power is produced ; for not only the mi- nute veflels of the whole external fkin for a time become inactive, as appears by their palenefs ; but the minute veflels of the lungs lofe much of their activity alfo by concert with thofe of the fkin, as appears from the difficulty of breathing at firll going into cold water. On emerging from the bath the fenforial power is thrown into great exer- tion by the ftimulus of the common degree of the warmth of the atmofphere, and a great production of animal heat is the confequence. The longer a perfbn continues in the cold bath {he greater muft be the prefent inertion of a great part of the fyftem, and in confequence a greater accumulation of fen- forial power. Whence M. Pome recommends fome melancholy patients to be kept from two to fix hours in fpring-water, and in baths ftill colder. 6. Decreafe the ftimulus for a time below the natural, and then increafe it above natural. The ef- fect of this procefs, improperly ufed, is feen in giving much food, or applying much warmth, to thofe who have been previoufly expofed to great hunger, or to great cold. The accumulated fenforial power o IS SECT. XII. 7. OF STIMULUS AND EXERTION. 103 is thrown into fo violent exertion, that inflam- mations and mortifications fupervene, and death clofes the cataftrophe. In many difeafes this method is the moft fuccefsful ; hence the bark in agues produces more certain effect after the pre- vious exhibition of emetics. In difeafes attended with violent pain, opium has double the effecl:, if venefection and a cathartic have been previoufly ufed. On this feems to have been founded the fuccefsful practice of Sydenham, who ufed vene- feclion and a cathartic in chlorofis before the exhi- bition of the bark, iteel, and opiates. 7. Prevent any unneceffary expenditure offen- forial power. Hence in fevers with debility, a decumbent pofture is preferred, with iilence, lit- tle light, and fuch a quantity ,of heat as may pre- vent any chill fenfation, or any coldnefs of the extremities. The pulfe of patients in fevers with debility increafes in frequency above ten pulfations in a minute on their riling out of bed. For the expenditure of fenforial power to preferve an erect pofture of the body adds to the general deficiency of it, and thus affects the circulation. 8. The longer in tijne and the greater in degree the quiefcence or inertion of an organ has been, fo that it ftiil retains life or excitability, the lefs fti- mulus mould at firft be applied to it. The quan- tity of ftimulation is a matter of great nicety to de- termine, where the torpor or quiefcence of the fibres has been experienced in a great degree, or for a confiderable time, as in cold fits of the ague, in continued fevers with great debility, or in peo- ple famifhed at fea, or perifhing with cold. In the two laft cafes, very minute quantities of food mould be firft fupplied, and very few additional degrees of heat. In the two former cafes, but lit- tle ftimulus of wine or medicine, above what they had been lately accuftomed to, fliould be exhibited, and 104 OF STIMULUS AND EXERTION. SECT. XII. 7. and this at frequent and ftated intervals, fo that the effect of one quantity may be obferved before the exhibition of another. If thefe circumftances are not attended to, as the fenforial power becomes accumulated in the quief- cent fibres, an inordinate exertion takes place by the increafe of ftimulus acting on the accumulated quantity of fenforial power, and either the para- lyfis, or death of the contractile fibres enfues, from the total expenditure of the fenforial power in the affected organ, owing to this increafe of exertion, like the debility after intoxication. Or, fecondly, the violent exertions above mentioned produce painful fenfation, which becomes a new ftimulus, and by thus producing inflammation, and increaf- ing the activity of the fibres already too great, fooner exhaufts the whole of the fenforial power in the acting organ, and mortification, that is. the death of the part, f upervenes. Hence there have been many inftances of peo- ple, whofe limbs have been long benumbed by ex- pofure to cold, who have loft them by mortifica- tion on their being too haftily brought to the fire ; and of others, who were nearly famifhed at fea, who have died foon after having taken not more than an uiual meal of food. I have heard of two well-attefted inftances of patients in the cold fit of ague, who have died from the exhibition of gin and vinegar, by the inflammation which enfued. And in many fevers attended with debility, the unlimited ufe of wine, and the wanton application of blifters, I believe, has deftroyed numbers by the debility confequent to too great ftimulation, that is, by the exhauftion of the fenforial power by its inordinate exertion. Wherever the leaft degree of intoxication exifts, a proportional debility is the confequence ; but there is a golden rule by which the neceffary and ufeful SECT. XII. 7. OF STIMULUS AND EXERTION. 105 ufeful quantity of flimulus in fevers with debility- may be afcertained. When wine or beer are exhi- bited either alone or diluted with water, if the pulfe becomes flower the ilimulus is of a proper quantity ; and ihould be repeated every two or three hours, or when the pulfe again becomes quicker. In the chronical debility brought on by drink- ing fpirituousor fermented liquors, there is another golden rule by which I have fuccefsfully directed the quantity of fpirit which they may fafely leflen, for there is no other means by which they can re- cover their health. It fliould be premifed, that where the power of digeftion in thefe patients is totally deftroyed, there is not much reafon to ex- peel a return to healthful vigour. I have directed feveral of thefe patients to omit one fourth part of the quantity of vinous fpirit they have been lately accuftomed to, and if in a fortnight their appetite increafes, they are advifed to omit another fourth part ; but if they perceive that their digeftion becomes impaired from the want of this quantity of fpirituous potation, they are advifed to continue as they are, and rather bear the ills they have, than rifk the encounter of greater. At the fame time flem-meat with or with- out fpice is recommended, with Peruvian bark and fteel in fmall quantities between their meals, and half a grain of opium or a grain, with five or eight grains of rhubarb at night.^ SECT. io6 OF VEGETABLE ANIMATION. SECT. XIII. i. — -tii! SECT. XIII. OF VEGETABLE ANIMATION. I. i. Vegetables are irritable* mimofa, dioncca mufci- pitla. Vegetable fecretions. 2. Vegetable buds are inferior animals^ are liable to greater or lefs irrita- bility. II. Stamens and piftils of plants /hew marks of jenfibility. III. Vegetables poffefs fome degree of volition. IV. Motions of plants are affociated like ih of e of animals* V. i. Vegetable ftruElure like that of animals > their anthers and fligmas are living crea- tures. Male- flowers of Vaiiifneria. i. Whether 'vegetables poffefs ideas ? *They have organs of fenfe as of touch and f melt 9 and ideas of external things ? I. |. The fibres of the vegetable world, as well as thofe of the animal, are excitable into a variety of motion by irritations of external objects. This appears particularly in the mimofa or feniitive plant, whofe leaves contract on the flighted injury ; the dionsea mufcipula, which was lately brought over from the marfhes of America, prefents us with another curious inflance of vegetable irritability ; its leaves are armed with fpines on their upper edge, and are fpread on the ground around the flem ; when an infect creeps on any of them in its paffage to the flower or feed, the leaf {huts up like a fleel rat-trap, and deftroys its enemy. See Botanic Garden, Part II. note on Silene. The various fecretions of vegetables, as of odour, fruit, gum, refin, wax, honey, feem brought about in the fame manner as in the glands of animals ; the taflelefs moifture of the earth is converted by the hop-plant into a bitter juice > as by the cater- pillar SECT. XIII. i. OF VEGETABLE ANIMATION. 107 pillar in the nut-fhell, the fweet kernel is converted into a bitter powder. While the power of abforp- tion in the roots and barks of vegetables is excited into aftion by the fluids applied to their mouths like the lacteals and lymphatics of animals. 2. The individuals of the vegetable world may be confidered as inferior or lefs perfect animals ; a tree is a congeries of many living buds, and in this refpect refembles the branches of coralline, which are a congeries of a multitude of animals. Each of thefe buds of a tree has its proper leaves or petals, for lungs, produces its viviparous or its oviparous offspring in buds or feeds ; has its own roots, which extending down the ftem of the tree are interwo- ven with the roots of the other buds, and form the bark, which is the only living part of the item, is annually renewed, and is fuperinduced upon the former bark, which then dies, and with its ftag- nated juices gradually hardening into wood forms the concentric circles, which we fee in blocks of timber. The following circumftances evince the indivi- duality of the buds of trees. Firft, there are many trees, whofe whole internal wood is periihed, and yet the branches are vegete and healthy. Secondly, the fibres of the barks of trees are chieffy longitu- dinal, refembling roots, as is beautifully feen in thofe prepared barks, that were lately brought from Otaheita. Thirdly, in horizontal wounds of the bark of trees, the fibres of the upper lip are always elongated downwards like roots, but thofe of the lower lip do not approach to meet them. Fourthly, if you wrap wet mofs round any joint of a vine, or cover it with moift earth, roots will {hoot out from it. Fifthly, by the inoculation or engrafting of trees many fruits are produced from one item. Sixthly, a new tree is produced from a branch plucked from an old one, and fet in the ground. I Whence lo8 OF VEGETABLE ANIMATION. SECT. XIII. 2. Whence it appears that the buds of deciduous trees are fo many annual plants, that the bark is a con- texture of the roots of each individual bud ; and that the internal wood is of no other ufe but to fupport them in the air, and that thus they refera- ble the animal world in their individuality. The irritability of plants, like that of animals, appears liable to be increafed or decreafed by habit ; for thofe trees or fhrubs, which are brought from a colder climate to a warmer, put out their leaves and bloflbms a fortnight fooner than the indige- nous ones. ProfefTor Kalm, in his Travels in New York, obferves that the apple-trees brought from England bloffom a fortnight fooner than the native ones. In our country the fhrubs, that are brought a de- gree or two from the north, are obferved to flou- rifh better than thofe, which come from the fouth. The Siberian barley and cabbage are faid to grow larger in this climate than the fimilar more fouthern vegetables. And our hoards of roots, as of pota- toes and onions, germinate with lefs heat in fpring, after they have been accuftomed to the winter's cold, than in autumn after the fummer's heat. II. The ftamens and piftils of flowers fhew evident marks of fenfibility, not only from many of the ftamens and fome piftils approaching towards each other at the feafon of impregnation, but from many of them clofing their petals and calyxes during the cold parts of the day. For this cannot be afcrib- ed to irritation, becaufe cold means a defect of the ftimulus of heat ; but as the want of accuftomed ftimuli produces pain, as in coldnefs, hunger, and thirft of animals, thefe motions of vegetables in doling up their flowers muftbe afcribed to the difa- greeable fenfation, and not to the irritation of cold. Others clofe up their leaves during darknefs, which, like SECT. XIII. 4. OF VEGETABLE ANIMATION. 109 like the former, cannot be owing to irritation, as the irritating material is withdrawn. The approach of the anthers in many flowers to the ftigmas, and of the piftils of fome flowers to the anthers, muft be afcribed to the pallion of love, and hence belongs to fenfation, not to Irritation. III. That the vegetable world poflefies fome de- gree of voluntary powers, appears from their ne- ceflity to ileep, which we have (hewn in Sect. XVIII. to confift in the temporary abolition of vo- luntary power. This voluntary power feems to be exerted in the circular movement of the tendrils of vines, and other climbing vegetables ; or in the efforts to turn the upper furface of their leaves, or their flowers to the light. IV. The aflbciations of fibrous motions are ob- fervable in the vegetable world, as well as in the animal. The diviiions of the leaves of the fenfitive plant have been accuftomed to contract at the fame time from the abfence of light ; hence if by any other circumflance, as a flight ftroke or injury, one divifion is irritated into contraction, the neigh- bouring ones contract alfo, from their motions being affociated with thofe of the irritated part. So the various ftamina of the clafs of fyngenefia have been accuftomed to contract together in the evening, and thence if you ftimulate one of them with a pin, according to the experiment of M. Colvolo, they all contract from their acquired af- fociations. To evince that the collapfing of the fenfitive plant is not owing to any mechanical vibrations propa- gated along the whole branch, when a fingle leaf is ftruck with the finger, a leaf of it was flit with (harp fcifibrs, and fome feconds of time palled be- fore the plant feemed fenfible of the injury ; and then the whole branch collapfed as far as the prin- 1 2 cipal I io OF VEGETABLE ANIMATION. SECT. XIII. 5 . cipal ftem : this experiment was repeated feveral times with the leaft poffible impulfe to the plant. V. i. For the numerous circumftances in which vegetable buds are analogous to animals, the reader is referred to the additional notes at the end of the Botanic Garden, Part I. It is there (hewn, that the roots of vegetables refembie the lacteal fyi- temof animals; the fap-veffels in the early fpring, I before their leaves expand, are analogous to the placental veffels of the foetus ; that the leaves of land-plants refembie lungs, and thofe of aquatic plants the gills of fifli; that there are other fyilems of veffels refembling the vena portarum of quadru- peds, or the aorta of fifti ; that the digeftive power of vegetables is fimilar to that of animals convert- ing the fluids, which they abforb, into fugar ; that their feeds refembie the eggs of animals, and their buds and bulbs their viviparous offspring. And, laftly, that the anthers and fiigmas are real animals, attached indeed to their parent tree like polypi or coral infects, but capable of fpontaneous motion : that they are affected with the paffion of love, and furnifhed with powers of reproducing their fpecies, and are fed with honey like the moths and butter- flies, which plunder their nectaries. See Botanic Garden, Part I. add. note XXXIX. The male flowers of vallifneria approach ftili nearer to apparent animality, as they detach them- felves from the parent plant, and float on the fur- face of the water to the female ones. Botanic Garden, Part II. Art. Vallifneria. Other flowers of the claffes of monecia and diecia, and polygamia, difcharge the fecundating farina, which floating in the air is carried to the iHgma of the female flow- ers, and that at confiderable diftances. Can this be effected by any fpecific attraction ? or, like the diffufion of the odorous particles of flowers, is it left to the currents of winds, and the accidental mifcarriages SECT. XIII. 5. OF VEGETABLE ANIMATION. 1 1 1 mifcarriages of it counteracted by the quantity of its produclion ? 2. This leads us to a curious enquiry, whether vegetables have ideas of external things ? As all our ideas are originally received by our fenfes, the queftion may be changed to, whether vegetables poflefs any organs of fenfe ? Certain it is, that they poflefs a fenfe of heat and cold, another of moifture and drynefs, and another of light and darknefs ; for they clofe their petals occafionally from the pre- fence of cold, moifture, or darknefs. And it has , been already fhewn, that thefe actions cannot be performed (imply from irritation, becaufe cold and darknefs are negative quantities, and on that ac- count fenfation or volition are implied, and in con- fequence a fenforium or union of their nerves. So when we go into the light, we contract the iris ; not from any ftimulus of the light on the fine muf- cles of the iris ; but from its motions being aflb- ciated with the fenfation of too much light on the retina : which could not take place without a fen- forium or center of union of the nerves of the iris with thofe of villon. See Botanic Garden, Part I, Canto 3. 1. 440. note. Beiides thefe organs of fenfe, which diftinguifh cold, moifture, and darknefs, the leaves of rnimo- fa, and of dionxa, and of drofera, and the ftamens of many flowers, as of the berbery, and the nu- merous clafs of fyngene(ia? are fenfible to mechanic impact, that is, they poflefs a fenfe of touch, as well as a common fenforium ; by the medium of which their mufcles are excited into action. Laftly, in many flowers the anthers, when mature, ap- proach the ftigrna, in others the female organ ap- proaches to the male. In a plant of coilinibnia, a branch of which is now before me, the two yellow ftamens are about three eighths of an inch high, and diverge from each other, at an angle of about fifteen I iz OF VEGETABLE ANIMATION. SECT. XIII. 5. fifteen degrees, the purple flyle is half an inch high, and in fome flowers is now applied to the itamen on the right hand, and in others to that of the left ; and will, I fuppofe, change place to-morrow in thofe, where the anthers have not yet effufed their powder. I afk, by what means are the anthers in many flowers, and fligmas in other flowers, directed to find their paramours? How do either of them know, that the other exifts in their vicinity ? Is this curious kind of ftorge produced by mechanic attraction, or by the fenfation of love ? The latter opinion is fupported by the ftrongeft analogy, be-? caufe a reproduction of the fpecies is the confe- quence ; and then another organ of fenfe muft be wanted to direct thefe vegetable amourettes to find each other, one probably analogous to our fenfe of fmell, which in the animal world directs the new- born infant to its fource of nourifhment, and they may thus poffefs a faculty of perceiving as well as '\ of producing odours. Thus, befides a kind of tafte at the extremities of their roots, fimilar to that of the extremities of our lacteal veffels, for the purpofe of felecling their proper food : and befides different kinds of irrita- bility refiding in the various glands, which fepa- rate honey, wax, reiin, and other juices from their blood; vegetable life feems to pofiefs an organ of fenfe to diftinguifh the variations of heat, another to diftinguifh the varying degrees of moifture, another of light, another of touch, and probably another analogous to our fenfe of fmell. To thefe muft be added the indubitable evidence of their pafiion of love, and I think we may truly conclude, that they are furnifhed with a common fenforium belonging to each bud, and that they muft occafion- repeat thofe perceptions either in their dreams or SECT. XIV. i. PRODUCTION OF IDEAS. 113 or waking hours, and confequently poflefs ideas of fo many of the properties of the external world, and of their own exiftence. SECT. XIV. OF THE PRODUCTION OF IDEAS. It Of material and immaterial beings. Doctrine of St. Paul. II. i. Of the fenfe of touch. Of folidity. 2. Of fgure. Motion. Time. Place. Space. Number. 3. Of the penetrability of matter. 4. Spirit of animation foffeffes folidity ', figure, wfibiUty, &c. Of fpirits and angels. 5. The exiftence of ex- ternal things. III. Of vi/ion. IV. Of hearing. V. Of f mil and iafte. VI. Of the organ of fenfe by which we perceive heat and cold, not by the fenfe of touch. VI I. Of the fenfe of extenfion, the whole of the locomotive mufcles may be confidered as one or- gan of fenfe. VIIL Of- the fenfe 5 of hunger, thirft, want offreftj air, fuckling children, and luft. 1 X , Of many other organs of fenfe belonging to the glands. Of pairful fenf at ions from the excefs of light, prejjtlire^ heat, itching, cauflics, and eleclricity. I. PHILOSOPHERS have been much perplexed to underftand, in what manner we become ac- quainted with the external world ; infomuch that Dr. Berkley even doubted its exiftence, from having obferved (as he thought) that none of our ideas refemble their correfpondent objects. Mr. Hume aflerts, that our belief depends on the greater dif- tinclncfs ii4 PRODUCTION OF IDEAS. SECT. XIV. i. tinctnefs or energy of our ideas from perception ; and Mr. Reid has lately contended, that our belief of external objects is an innate principle neceflarily joined with our perceptions. So true is the obfervation of the famous Mai- branch, " that our fenfes are not given us to dif- cover the eflences of things, but to acquaint us with the means of preferving our exiftence," (L. I. ch. v.) a melancholy reflection to philofophers ! Some philofophers have divided all created beings into material and immaterial : the former including all that part of being, which obeys the mechanic laws of action and reaction, but which can begin no motion of itfelf ; the other is the caufe of all motion, and is either termed the power of gravity, or of fpecific attraction, or the fpirit of animation. This immaterial agent is fuppofed to exift in or with matter, but to be quite diftincl from it, and to be equally capable of exiftence, after the matter, which now pofleffes it, is decom- pofed* Nor is this theory ill fupported by analogy, fince heat, electricity, and magnetifm, can be given to or taken from a piece of iron ; and muft therefore exift, whether feparated from the metal, or com- bined with it. From a parity of reafoning, the fpirit of animation would appear to be capable of cxifting as well feparately from the body as with it. I beg to be underftood, that I do not wifli to difpute about words, and am ready to allow, that the powers of gravity, fpecific attraction, electri- city, magnetifm, and even the fpirit of animation, may confift of matter of a finer kind ; and to be- lieve, with St. Paul and Malbranch, that the ulti- mate caufe only of all motion is immaterial, that is God. St. Paul fays, " in him we live and move, and have our being j" and in the i5th chapter to the SECT. XIV. 2. PRODUCTION OF IDEAS. 1 1 5 the Corinthians, diftinguifhes between the pfyche or living fpirit, and the pneuma or reviving fpi- rit. By the words fpirit of animation or fenibrial power, I mean only that animal life, which man- kind poflefies in common with brutes, and in fome degree even with vegetables, and leave the con- fideration of the immortal part of us, which is the object of religion, to thole who treat of revela- tion. II. i. OftheSenfe of Touch. THE firft idea we become acquainted with, arc thofe of the fenfe of touch ; for the foetus muft ex- perience fome varieties of agitation, and exert fome mufcular action, in the womb ; and may with great probability be fuppofed thus to gain fome ideas of its own figure, of that of the uterus, and of the tenacity of the fluid, that furrounds it, (as appears from the fafts mentioned in the fucceeding Section upon Inftinct.) Many of the organs of fenfe are confined to a fmall part of the body, as the noftrils, ear, or eye, whilft the fenfe of touch is diffufed over the whole fkin, but exifts with a more exquifite degree of delicacy at the extremities of the fingers and thumbs, and in the lips. The fenfe of touch is thus very commodioufly difpofed for the purpofe of encompailing fmaller bodies, and for adapting itfelf to the inequalities of larger ones. The figure of fmall bodies feems to be learnt by children by their lips as much as by their fingers ; on which account they put every new object to their mouths, when they are fatiated with food, as well as when they are hungry. And puppies feem to learn their ideas of figure principally by the lips in their mode of play. We n PRODUCTION OF IDEAS. SECT. XIV. 7, Add to this, that the lungs, though eafily ftimiu lated into inflammation , are not fenfible to heat. See Clafs, III. i. i. ic, VII. Of the Senfe of Extenfion. THE organ of touch is properly the fenfe of pref- fure, but the mufcular fibres themfelves conftitute the organ of fenfe, that feels extenfion. The fenfe of preffure is always attended with the ideas of the figure and folidity of the object, neither of which accompany our perception of extenfion. The whole fet of mufcles, whether they are hollow ones, as the heart, arteries, and inteftines, or lon- gitudinal ones attached to bones, contract them- ielves, whenever they are ftimulated by forcible elongation ; and it is obfervable, that the white mufcles, which conftitute the arterial fyftem, feem to be excited into contraction from no other kinds of ftimulus, according to .the experiments of Haller, And hence the violent pain in fome inflammations, as in the paronychia, obtains immediate relief by cutting the membrane, that was ftretched by the tumour of the fubjacent parts. Hence the whole mufcular fyftem may be confi- dered as one organ of fenfe, and the various atti- tudes of the body, as ideas belonging to this organ, of many of which we are hourly confcious, while many others, like the irritative ideas of the other fenfes, are performed without our attention. When the mufcles of the heart ceafe to aft, the refluent blood again diftends or elongates them ; and thus irritated they contract as before. The fame happens to the arterial fyftem, and I fuppofe to the capillaries/ inteftines, and various glands of the body, When the quantity of urine, or of excrement, ftracted ideas ; thus fweetnefs, and whitenefs, and folidity, are received at the fame time from a lump of fugar, yet I can recollect any of thefe qualities without thinking of the others, that were excited along with them. When ideas are fo far abftracted as in the above example, they have been termed fimple by the writers of metaphyfics, and^feem indeed to be more complete repetitions of the ideas or fenfual motions, originally excited by external objects. Other clailes o£. thefe ideas, where the abftrac- tion has not been fo great, have been termed, by Mr. Locke, modes, fubftances, and relations, but they feem only to differ in their degree of abftrac- tion from the complex ideas that were at firft ex> cited ; for as thefe complex or natural ideas are themfelves imperfect copies of their correfpondent perceptions, fo thefe abftract or general ideas are only ftiil more imperfect copies of the fame per- ceptions. Thus when I have feen an object but once, as a rhinoceros, my abftract idea of this ani- mal is the fame as my complex one. I may think more or lefs diftin&ly of a rhinoceros, but it is the very rhinoceros that I faw, or fome part or proper- ty of him, which recurs to my mind. But when any clafs of complex obje&s becomes the fubject of converfation, of which I have feen many individuals, as a caftle or an army, fome property or circumftance belonging to it is peculi- arly alluded to ; and then I feel in my own mind, that my abftracfc idea of this complex object is only an idea of that part, property, or attitude of it, that employs the prefent converfation, and varies with every fentence that is fpoken concerning it. So if any ooe fhould fay, " one may fit upon a horfe i3» CLASSES OF IDEAS. SECT. JCV. t. horfe fafer than on a camel," my abftract idea of the two animals includes only an outline of the level back of the one, and the gibbofity on the back of the other. What noife is that in the ftreet ? — Some horfes. trotting over the pavement. Here my idea of the horfes includes principally the fhape and motion of their legs. So alfo the abftract ideas of goodnefs and courage are Hill more imperfect reprefentations of the ob- jects they were received from 5 for here we ab- ilract the material parts, and recollect only the qualities. Thus we abflract fo much from fome of our* complex ideas, that at length it becomes difficult to determine of what perception they partake ; and in many inftances out idea feems to be no other than of the found or letters of the word, that Hands for the colle&ive tribe, of which we are faid to have an abftra&ed idea, as noun, verb, chi- inaera, apparition* 6. Ideas have been divided into thofe of percep- tion and thofe of reflection, but as whatever is perceived muft be external to the organ that perceives it, all our ideas muft originally be ideas of perception. 7. Others have divided our ideas into thofe of memory, and thofe of imagination ; they have faid that a recollection of ideas in the order they were received conftitutes memory, and without that order imagination ; but all the ideas of imagina- tion, excepting the few that are termed -fimple ideas, are parts of trains or tribes in the order they were received ; as if I think of a fphinx, or a griffin, the fair face, bofom, wings, claws, tail, are all complex ideas in the order they were received : and it behoves the writers, who ad- ' here SECT. XV. CLASSES OF IDEAS. 139 here to this definition, to determine, how^ fmall the trains muft be, that fhall be called imagi- nation ; and how great thofe, that fhall be called memory, Others have thought that the ideas of memory have a greater vivacity than thofe of imagination : but the^ideas of a perfon in fleep, or in a waking reverie, where the trains connected with fenfation are uninterrupted, are more vivid and diftincl: than thofe of memory, fo that they cannot be diflin- guifhed by this criterion. The very ingenious author of the Elements of Criticifm has defcribed what he conceives to be a fpecies of memory, and calls it ideal prefence ; but the inftances he produces are the reveries of fenfa- tion, and are therefore in truth connections of the imagination, though they are recalled in the order they were received. The ideas connected by aflbciation are in com- mon difcourfe attributed to memory, as we talk of memorandum. rings, and tie a knot on our handkerchiefs to bring fomething into our minds at a diftance of time. And a fchool-boy, who can repeat a thoufand unmeaning lines in Lilly's Grammar, is faid to have a good memory. But thefe have been already fhewn to belong to the clafs of aflbciation j and are termed ideas of fuggeftion. II. Laftly, the method already explained of claf- ling ideas into thofe excited by irritation, fenfation, volition, or aflbciation, we hope will be found more convenient both for explaining the operations of the mind, and for comparing them with thofe of the body ; and for the illuflration and the cure of the difeafes of both, and which we fliall here reca- pitulate. VOL. I. L i. Irritative 14® CLASSES OF IDEAS. SECT. XV. 3; 1. Irritative ideas are thofe, which are preceded by irritation, which is excited by objects external to the organs of fenfe : as the idea of that tree, which either I attend to, or which Khun in walking near it without attention. In the former cafe it is termed perception, in the latter it is termed limply an irritative idea. 2. Senfitive ideas are thofe, which are preceded by the fenfation of pleafure or pain ; as the ideas, which conftitute our dreams or reveries, this is called imagination. 3. Voluntary ideas are thofe, which are preceded by voluntary exertion, as when I repeat the alpha- bet backwards : this is called recollection. 4. Aflbciate ideas are thofe, which are preceded by other ideas or mufcular motions, as when we think over or repeat the alphabet by rote in its lifual order ; or fing a tune we are accuftomed to 5 this is called fuggeftion. III. i. Perceptions fignify thofe ideas, which are preceded by irritation and fucceeded by the fenfation of pleafure or pain, for whatever excites our attention interefts us ; that is, it is accompanied with pleafure or pain ; however flight may be the degree or quantity of either of them. The word memory includes two clafTes of ideas, either thofe which are preceded by voluntary ex- ertion, or thofe which are fuggefted by their aflb- ciations with other ideas. 2. Reafoning is that operation of the fenforium, by which we excite two or many tribes of ideas ; and then re-excite the ideas, in which they differ, or correfpond. If we determine this difference, it is called judgment; if we in vain endeavour to de- termine it, it is called doubting. IP SECT. XV. 3. CLASSES OF IDEAS. If we re-excite the ideas, in which they differ, it is called diftinguifhing. If we re-excite thofe in which they correfpond, it is called comparing. 3. Invention is an operation of the fenforium, by which we voluntarily continue to excite one train of ideas, fuppofe the defign of railing water by a machine ; and at the fame time attend to all other ideas, which are connected with this by every kind of catenation ; and combine or fepa- rate them voluntarily for the purpofe of obtaining fome end. For we can create nothing new, we can only combine or feparate the ideas, which we have al- ready received by our perceptions : thus if I wifli to reprefent a monfler, I call to my mind the ideas of every thing difagreeable and horrible, and com- bine the naftinefs and gluttony of a hog, the ftupi^ dity and obftinacy of an afs, with the fur and awk- wardnefs of a bear, and call the new combination. Caliban. Yet fuch a monfter may exift in nature, as all his attributes are parts of nature. So when I wifti to reprefent every thing, that is excellent, and amiable ; when I combine benevolence with cheerfulnefs, wifdom, knowledge, tafte, wit, beau- ty of perfon, and elegance of manners, and aflb- ciate them in one lady as a pattern to the world, it is called invention ; yet fuch a perfon may exift,—- fuch a perfon does exift ! — It is • < • . , who is as much a monfter as Caliban. 4. In refpecl to confcioufnefs, we are only con- fcious of our exiftence, when we think about it ; as we only perceive the lapfe of time, when we at- tend to it ; when we are bufied about other objects, neither the lapfe of time nor the confcioufnefs of our own exiftence can occupy our attention. Hence, when we think of our own exiftence, we only ex- L 2 cite j 14* CLASSES OF IDEAS. SECT. XV. 3. cite abftracted or reflex ideas (as they are termed), of our principal pleafures or pains, of our defires or avernons, or of the figure, folidity, colour, or other properties of our bodies, and call that aft of the .fenforium a confcioufnefs of our exiftence. Some philofophers, I believe it is Des Cartes, has faid, " I think, therefore I exift." But this is not right reafoning, becaufe thinking is a mode of ex- iftence ; and it is thence only faying, " I exift, therefore I exift." For there are three modes of exiftence, or in the language of grammarians, three kinds of verbs. Firft, limply I am, or exift. Secondly, I am acting, or exift in a ftate of activity, as I move. Thirdly, I am fuffering, or «xift in a ftate of being acted upon, as I am moved. The when, and the where, as applica- ble to this exiftence, depends on the fucceflive motions of our own or of other bodies ; and on their refpective fituations, as fpoken of Seel. XIV. 2. 5. 5. Our identity is known by our acquired ha- bits or catenated trains of ideas and mufcular motions ; and perhaps, when we compare infan- cy with old age, in thofe alone can our identity be fuppofed to exift. For what elfe is there of fimilitude between the firft fpeck of living en- tity and the mature man? — every deduction of reafoning, every fentiment or paffion, with every fibre of the corporeal part of our fyftem, has been fubject almoft to annual mutation ; while fome catenations alone of our ideas and mufcular actions have continued in part unchanged. By the facility, with which we can in our waking hours voluntarily produce certain iucceffive trains of ideas, we know by experience, that we have before reproduced them j that is, we are confcious of SECT. XV. 3. CLASSES OF IDEAS. 143 of a time of our exiftence previous to the prefent time ; that is, of our identity now and heretofore. It is thefe habits of action, thefe catenations of ideas and mufcular motions, which begin with life, and only terminate with it ; and which we can in fome meafure deliver to ourpoflerity j as explained in Sea. XXXIX. 6. When the progreflive motions of external bodies make a part of our prefent catenation of ideas, we attend to the lapfe of time ; which appears the longer, the more frequently we thus attend to it ; as when we expect fomething at a certain hour, which much interefts us, whether it be an agreeable or difagreeable event ; or when we count the paffing feconds on a ftop-watch. When an idea of our own perfon, or a reflex idea of our pleafures and pains, defires and a- verfions, makes a part of this catenation, it is termed confcioufnefs ; and if this idea of con- fcioufnefs makes a part of a catenation, which we excite by recollection, and know by the fa- cility with which we excite it, that we have be- fore experienced it, it is called identity, as ex- plained above. 7. In refpecl: to freewill, it is certain, that we cannot will to think of a new train of ideas, with- out previoufly thinking of the firft link of it ; as I cannot will to think of a black fwan, without pre- vioufly thinking of a black fwan. But if I now think of a tail, I can voluntary recollecl all animals which have tails ; my will is fo far free, that I can purfue the ideas linked to this idea of tail, as far as my knowledge of the fubjecl: extends ; but to will without motive is to will without defire or averfion ; which is as abfurd as to feel without pleafure or pain : they are both folecifms in the terms CLASSES OF IDE AS. SECT. XV. 3. terms. So far are we governed by the catenations of motions, which affect both the body and the mind of man, and which begin without our irri- tability, and end with it, SECT. SECT. XVI. i, OF INSTINCT. 145 SECT. XVI. OF INSTINCT. HAUD EQU1DEM CREDO, QUIA SIT DIVINITUS ILLIS INGENIUM, AUT RERUM FATO PRUDENTIA MAJOR* VIRG. GEORG. L. I. 415. I. Inftinclive aftions defined. Of connate pajfions. II. Of the fenfations and motions of the fetus in the womb. III. Some animals are more perfectly formed than others before nativity. Of learning to walk. IV. Of ihe fw allowing, breathing, fucking pecking, and lapping of young animals. V. Of the fenfe of f me II, and its ufes to animals. Why cats do not eat their kit- tens. VI. Of the accuracy of fight in mankind, and their fenfe of beauty. Of the fenfe of touch in ele- phants, monkies, beavers, men. VII. Of natural language. VIII. The origin of natural language; i. the language of fear ; 2. of grief ; 3. of tender pleafure ; 4. of ferene pleafure ; 5. of 'anger : 6. of attention. IX. Artificial language of turkies^ hens9 ducklings, wagtails, cuckoos, rabbits, dogs^ and night- ingales. X. Of mufic \ . of tooth -edge ; of a good ear; of architecture. XI. Of acquired knowledge ; of foxes ) rooks i fieldfares, lapwings, dags, cats, horfes9 crows 9 and pelicans. XII. Of birds of paffage, dor~ mice, fnakes, bats, f wallows, quails* ringdoves, Jiare, chaffinch, hoopoe, chatterer, hawfinch, crofsbtll, rails and M OF INSTINCT. SECT. XVI. i. and cranes. XIII. Of birds nefts ; of the cuckoo; of /wallows nefls ; of the taylor bird. XIV. Of the old foldier ; of haddocks, cods, and dogfjh ; of the remora ; of crabs, herrings, and falmon. XV. Of fpiders, caterpillars, ants, and the ichneumon. XVI. i. Of locufts, gnats; 2. bees; 3. dormice ', flies , worms, ants, and wafps. XVII. Of the faculty that dlftlnguljhes man from the brutes. I. ALL thofe internal motions of animal bodies, which contribute to digeft their aliment, produce their fecretions, repair their injuries, or increafe their growth, are performed without our atten- tion or con fcioufn el's, They exift as well in our fleep, as in our waking hours, as well in the foetus during the time of geftation, as in the infant after nativity, and proceed with equal regularity in the vegetable as in the animal fyftem. Thefe motions have been Ihewn in a former part of this work to depend on the irritations of peculiar fluids, and as they have never been claffed amongfl the inftinctive actions of animals, are precluded from our prefent difquifition. But all thofe actions of men or animals, that are attended with confcioufnefs, and feem neither to have been directed by their appetites, taught by their experience, nor deduced from obfervation or tradition, have been referred to the power of in- fHnct.. And this power has been explained to be a divine fomething, a kind of infpiration ; whilft the poor animal, that poflefTes it, has been thought lit- tle better than a machine ! The irkfo?nenefs, that attends a continued attitude of the body, or the pains, that we receive from heat, cold, hunger, or other injurious circumf- tances, SECT. XVI. 2. OF INSTINCT. tances, excite us to general locomotion : and our fenfes are fo formed and conftituted by the hand of na- ture, that certain objects prefent us with pleafure, others with pain, and we are induced to approach and embrace thefe, to avoid and abhor thofe, as fuch fenfations direcl us. Thus the palates of fome animals are gratefully affected by the maftication of fruits, others of grains, and others of flefli ; and they are thence infligated to attain, and to confume thofe mate- rials ; and are furnifhed with powers of mufcular motion, and of digeftion proper for fuch pur. pofes. Thefe fenfations and dejtres conftitute a part of our fyftem, as our mufcles and bones conftitute ano- ther part : and hence they may alike be termed natural or connate ; but neither of them can pro- perly be termed inftinclive : as the word inftinct in its ufual acceptation refers only to the aftions of animals, as above explained ; the origin of thefe aftions is the fubjecl of our prefent enquiry. The reader is intreated carefully to attend to this definition of inftinftive aftions, left by ufing the word inftincl without adjoining any accurate idea to it, he may not only include the natural defires of love and hunger, and the natural fenfations of pain or pleafure, but the figure and contexture of the body, and the faculty of reafon itfelf under this general term. II. We experience fome fenfations, and perform fome actions before our nativity ; the fenfations of cold and warmth, agitation and reft, fulnefs arid inanition, are inftances of the former ; and the repeated ftruggles of the limbs of the foetus, which begin about the middle of geftation, and thofe motions 148 OF INSTINCT. SECT. XVI. a. motions by which it frequently wraps the umbilical chord around its neck or body, and even fome- times ties it on a knot ; are inftances of the latter. SmeJiie's Midwifery, (Vol. I. p. 182.) By a due attention to thefe circumftances many of the actions of young animals, which at firft fight feemed only referable to an inexplicable in (line!:, will appear to have been acquired like all other ani- mal actions, that are attended with confcioufnefs, by the repeated efforts of our mufcles under the conduft of our fenfations or dejires. The chick in the fheli begins to move its feet and legs on the fixth day of incubation (Mattrecian, p. 138) ; or on the feventh day, (Langley); after- wards they are feen to move themfelves gently in the liquid that furrounds them, and to open and fhut their mouths, (Harvei, de Generat. p. 62, and 197. Form de Poulet. ii. p. 129). Puppies before the membranes are broken, that involve them, are feen to move themfelves, to put out their tongues, and to open and fhut their mouths, (Harvey, Gip- foo, Riolan, HallerJ. And calves lick themfelves and fwallow many of their hairs before their nati- vity: which however puppies do not, (Swam- merden, p. 319. Flemyng Phil. Tranf. Ann. 1755. 42.) And towards the end of geftation, the foetus of all animals are proved to drink part of the li- quid in which they fvvim, (Haller. Phyliol. T. 8. 204). The white of egg is found in the mouth and gizzard of the chick, and is nearly or quite confumed before it is hatched, (Harvie de Generat. 58). And the liquor amnii is found in the mouth and ftomach of the human foetus, and of calves ; and how elfe fhould that excrement be produced in the inteftines of all animals, which is voided in great SHCT. XVI. 3. OF INSTINCT. 149 great quantity foon after their birth ; (Gipfon, Med. Mays, Edinb. V. i. 13. Halleri Phyfiolog. T. 3. p. 318. and T. 8). In the ftomach of a calf the quantity of this liquid amounted to about three pints, and the hairs amongft it were of the fame colour with thofe on its ikin, (Blafii Anat. Animal, p. m. 122). Thefe facls are attefted by many other writers of credit, befides thofe above mentioned. 111. It has been deemed a furprifing inftance of inftincl:, that calves and chickens fhould be able to walk by a few efforts almoft immediately after their nativity : whilft the human infant in thofe countries where he is not incumbered with clothes, as in India, is five or fix months, and in our cli- mate almoft a twelvemonth, before he can fafely Hand upon his feet. The ftruggles of all animals in the womb muft refemble their mode of fwimming, as by this kind of motion they can beft change their attitude in water. But the fwimming of the calf and chicken refembles their manner of walking, which they have thus in part acquired before their nativity, and hence accompliih it afterwards with very few efforts, whilft the fwimming of the human crea- ture refembles that of the frog, and totally differs from his mode of walking. There is another circumftance to be attended to in this affair, that not only the growth of thofe peculiar parts of animals, which are firft wanted to fecure their fubfiftence, are in general furtheft advanced before their nativity : but fome animals come into the world more completely formed throughout their whole fyftem than others : and are thence much forwarder in all their habits of motion* 150 OF INSTINCT. SICT. XVI. 4* motion. Thus the colt, and the lamb, are much more perfect animals than the blind puppy, and the naked rabbit ; and the chick of the pheafant, and the partridge, has more perfect plumage, and more perfect eyes, as well as greater aptitude to loco- iriotion, than the callow neftlings of the dove, and of the wren. The parents of the former only find it neceffary to (hew them their food, and to teach them to take it up ; whilft thofe of the latter are obliged for many days to obtrude it into their gap- ing mouths. IV. From the facts mentioned in No. a. of this Section, it is evinced that the foetus learns to fwal- iow before its nativity ; for it is feen to open its mouth, and its ftomach is found filled with the liquid that furrounds it. It opens its mouth, either infligated by hunger, or by the irkfomenefs of a continued attitude of the mufcles of its face ; the liquor amnii, in which it fwims, is agreeable to its palate, as it coniifts of a nourifhing material, (Haller Phyf. T. 8. p. 204;. It is tempted to ex- perlence its tafte further in the mouth, and by a few efforts learns to fwallow, in the fame manner as we learn all other animal actions, which are attended with confcioufnefs, by the repeated efforts of our mufcles under the condutt of our fenfatlons or voli- tions. The infpiration of air into the lungs is fo totally different from that of fwallowing a fluid in which \ve are immerfed, that it cannot be acquired be- fore oar nativity. But at this time, when the circulation of the blood is no longer continued through the placenta, that fuffocating fenfation, which we feel about the precordia, when we are in want of frefli air, difagreeably affects the infant : and SECT. XVI. 4. OF INSTINCT. 151 and all the mufcles of the body are excited into action to relieve this oppreflion ; thofe of the bread, ribs, and diaphragm are found to anfwer this pur- pofe, and thus refpiration is difcovered, and is continued throughout our lives, as often as the oppreflion begins to recur. Many infants, both of the human creature, and of quadrupeds, ftrug- gle for a minute after they are born before they begin to breathe, (Haller Phyf. T. 8. p. 400. ib. pt. 2. p. i). Mr. Buffon thinks the action of the dry air upon the nerves of fmell of new-born ani- mals, by producing an endeavour to fneeze, may contribute to induce this firft infpiration, and that the rarefaction of the air by the warmth of the lungs contributes to induce expiration, (Hid. Nat. Tom. 4. p. 174). Which latter it may effect by producing a difagreeable ienfation by its delay, and a confequent effort to relieve it. Many children fneeze before they refpire, but not all, as far as I have obferved, or can learn from others.. At length, by the direction of its fenfe of fmell, or by the officious care of its mother, the young animal approaches the odoriferous rill of its future nourifhment, already experienced to fwallow. But in the act of fwallowing, it is neceflary nearly to clofe the mouth, whether the creature be immerfed in the fluid it is about to drink, or not : hence, when the child firft attempts to luck, it does not ilightly comprefs the nipple between its lips, and fuck as an adult perfon would do, by abforbing the milk ; but it takes the whole nipple into its mouth for this purpoie, compreffes it between its gums, and thus repeatedly chewing (as it were) the nip- ple, prefTes out the milk ; exactly in the fame manner as it is drawn from the teats of cows by the hands of 152 OF INSTINCT. SECT. XVI. ^ of the milkmaid. The celebrated Harvey obferves, that the foetus in the womb muft have fucked in a part of its nourishment, becaufe it knows how to fuck the minute it is born, as any one may expe- rience by putting a finger between its lips, and becaufe in a few days it forgets this art of fucking, and cannot without fome difficulty again acquire it, (Exercit. de Gener. Anim. 48). The fame obfer- vation is made by Hippocrates. A little further experience teaches the young animal to fuck by abforption, as well as by com- preffion ; that is, to open the cheft as in the be- ginning of refpiration, and thus to rarefy the air in the mouth, that the preffure of the denfer ex- ternal atmofphere may contribute to force out the milk. The chick yet in the fhell has learnt to drink by {wallowing a part of the white of the egg for its food ; but not having experienced how to take up and fwallow folid feeds, or grains, is either taught by the folicitous induftry of its mother ; or by many repeated attempts is enabled at length to diftinguifli and to fwallow this kind of nutri- ment. And puppies, though they know how to fuck like other animals from their previous experience in fwallowing, and in refpiration ; yet axe they long in acquiring the art of lapping with their tongues, which from the flaccidity of their cheeks, and length of their mouths, is afterwards a more convenient way for them to take in water. V. The fenfes of fmell and tafte in many other an\mals greatly exceed thofe of mankind, for in civilized fbciety, as our victuals are generally pre- pared by others, and are adulterated with fait, fpice, SECT. XVI. 5. OF INSTINCT. i 55 fpice, oil, and empyreuma, we do not hefitate about eating whatever is fet before us, and neglect to cultivate thefe fenfes : whereas other animals try every morfel by the fmell, before they take it into their mouths, and by the tafte before they fwallow it : and are led not only each to his pro- per nouriftiment by this organ of fenfe, but it aifo at a maturer age directs them in the gratification of their appetite of love. Which may be fur- ther underftood by confidering the fympathies of thefe parts defcribed in Clafs IV. 2. 1.7. While the human animal is directed to the object of his love by his fenfe of beauty, as mentioned in No. VI. of this Section. Thus Virgil, Georg. III. 250. Nonne vides, uttota tremor pertentat equorum Corpora, fi tantum notas odor attulit auras ? Nonne canis nidum veneris nafntus odore Qaeriut, et erranti trahitur fublambere lingua ? Refpuit at guftum cupidus, labiifq retra&is Elevat os, trepidanfque novis impellitur aeftria, Jnferit et vivum felici vomere femen. Quam tenui filo caecos adne&it amores Doda Venus, vitaeque monet renovare favillam ! ANON. The following curious experiment is related by Galen. " On directing a goat great with young I found a brifk embryon, and having detached it from the matrix, and fnatching it away before it faw its dam, I brought it into a certain room, where there were many veflels, fome filled with wine, others with oil, fome with honey, others with milk, or fome other liquor ; and in others were grains and fruits j we firit obferved the young animal 154 OF INSTINCT. SECT. XVI. fr animal get upon its feet, and walk ; then it fhook itfelf, and afterwards fcratched its fide with one of its feet : then we faw it fmelling to every one of thefe things, that were fet in the room; and when it had fmelt to them all, it drank up the milk." L. 6. de locis. cap. 6. Parturient quadrupeds, as cats, and bitches, and fows, are led by their fenfe of fmell to eat the pla- centa as other common food ; why then do they not devour their whole progeny, as is reprefented in an antient emblem of TIME ? This is faid fome- times to happen in the unnatural ftate in which we confine fows ; and indeed nature would feem to have endangered her offspring in this nice circum- flance ! But at this time the ftimulus of the milk in the tumid teats of the mother excites her to look out for, and to defire fome unknown circum- flance to relieve her. At the fame time the fmell of the milk attracts the exertions of the young , animals towards its fource, and thus the delighted mother difcovers a new appetite, as mentioned in Seel:. XIV. 3. and her little progeny are led to re- ceive and to communicate pleafure by this mod beautiful contrivance. VI. But though the human fpecies in fome of their fenfations are much inferior to other animals, yet the accuracy of the fenfe of touch, .which they poflefs in fo eminent a degree, gives them a great Superiority of underftanding ; as is well obferved by the ingenious Mr. Buffon. The extremities of other animals terminate in horns, and hoofs, and claws, very unfit for the fenfation of touch; whilft the human hand is finely adapted to encom- pafs its object with this organ of fenfe. * ' The SECT. XVI. 6. OF INSTINCT. 171 The elephant is indeed endued with a fine fenfe of feeling at the extremity of his probofcis, -and hence has acquired much more accurate ideas of touch and of light than moft other creatures. The two following inftances of the fagacity of thefe ani- mals may entertain the reader, as they^were told me by fome gentlemen of diftinct obfervatiori, and un- doubted veracity, who had been much converfant xvith our eaflern fettlements. Firft, the elephants that are ufed to carry the baggage of our armies, are put each under the care of one of the natives of Indoftan, and whilft himfelf and his wife go into the woods to collect leaves and branches of trees for his food, they fix him to the ground by a length of chain, and frequently leave a child yet unable to walk, under his protection : and the intelligent ani- mal not only defends it, but as it creeps about, when it arrives near the extremity of his chain, he wraps his trunk gently round its body, and brings it again into the centre of his circle. Secondly, the traitor elephants are taught to walk on a narrow path between two pit-falls, which are covered with turf, and then to go into the woods, and to feduce the wild elephants to come that way, who fall into thefe wells, whilft he pafles fafe between them : and it is univerfaliy observed, that thofe wild ele- phants that efcape the fnare, purfue the traitor with the utinoft vehemence, and if they can overtake him, which fometimes happens, they always beat him to death. The monkey has a hand well enough adapted for the fenfe of touch, which contributes to his great facility of imitation ; but in taking- objects with his hands, as a (lick or an apple, he puts his thumb on the fame fide of them with his fingers, inflead of counteracting the preffure of his fingers with it : from this neglect he is much flower in acquiring the figures of objects, as he is lefs able to determine VOL. I. N the i?2 OF INSTINCT. SECT. XVI. 6. the di fiances or diameters of their parts, or to dif- tinguifh their vis inertias from rheir hardnefs. Hel- vetius adds, that the fhonnefs of his life, his being fugitive before mankind, and his not inhabiting all climates, combine to prevent his improvement. (De PEfprif. T. i. p.) There is however at this time an old monkey (hewn in Exeter Change, London, who having loft his teeth, when nuts are given tar him, takes a flone into his hand, and cracks them with it one by one ; thus ufmg tools to effect his purpofe like mankind. The beaver is another animal that makes ufe of his hands, and if we may credit the reports of tra- vellers, is poffeiTed of amazing ingenuity. This however, Mr. Buffon affirms, is only where they exid in large numbers, and in countries thinly peo- pled with men ; while in France in their folitary flate they (hew no uncommon ingenuity. Indeed all the quadrupeds, that have collar-bones, (clavicular) ufe their fore- limbs in fome meafure as we ufe our hands, as the cat, fquirrel, tiger, bear and lion ; and as they exercife the fenfe of touch more univerfally than other animals, fo are they more fagacious in watching and furprifing their prey. All thofe birds, that ufe their claws for hands, as the hawk, parrot, and cuckoo, -appear to be more docile and intelligent ; though the gre- garious tribes of birds have more acquired know- ledge. Now as the image?, that are painted on the retina of the eye, are no other than figns, which recall to our imaginations the objects \ve had before exa- mined by the organ of touch, as is fully demon- ftratiid by Dr. Berkley, in his treatife on vifion j it follows that the human creature has greatly more accurate and diftinct fenfe of vifion than that of any other animal. Whence as he advances to maturity- he gradually acquires a fenfe of female beauty, which SECT. XVI. 6. OF INSTINCT. i7J which at this time directs him to the object of his new paflion. Sentimental love, as diflinguifhed from the ani- mal paffion of that name, with which it is frequent- ly accompanied, confifts in the defire or fenfation of beholding, embracing, and faluting a beautiful objeft. The character iftic of beauty therefore is that it is the object of love ; and though many other objects are in common language called beautiful, yet they are only called fo metaphorically, and ought to be termed agreeable. A Grecian temple may give us the pleafurable idea of fublimity, a Gothic temple may give us the pleafurable idea of Variety, and a modern houfe the pleafurable idea of utility ; mufic and poetry may infpire our love by afibciation of ideas ; but none of thefe, except metaphorically, can be termed beautiful ; as we have no wifh to embrace or falute them. Our perception of beauty confifts in our recogni- tion by the fenfe of vifion of thofe objects, firft, which have before infpired our love by the pleafure, which they have afforded to many of our fenfes : as to our fenfe of warmth, of touch, of fmell, of tafte, hunger and thirft ; and, fecondly, which bear any analogy of form to fuch objects. When the babe, foon after it is born into this cold world, is applied to its mother's bofom ; its fenfe of perceiving warmth is firft agreeably affect- ed ; next its fenfe of fmell is delighted with the odour of her milk; then its tafte is gratified by the flavour of it : afterwards the appetites of hunger and of thirft afford pleafure by the pofleflion of their objects, and by the iubfequent digeftion of the ali- ment; and, laftly, the fenfe of touch is delighted by the foftnefs and fmoothnefs of the milky foun- tain, the fource of fuch varietv of happinefs. N 2 All 174 OF INSTINCT. SECT.XVI.6, All thefe various kinds of pleafure at length become aflbciated with the form of the mother's bread; which the infant embraces with its hands, preffes with its lips, and watches with its eyes ; and thus acquires more accurate ideas of the form of its mother's bofom, than of the odour and flavour or warmth, which it perceives bv its other fenfes. And hence at our maturer years, when any object of vifion is prefented to us, which by its waving 9r fpiral lines bears any fimilitude to the form of the female bofom, whether it be found in a land- fcape with foft gradations of rifmg and defcending furface, or in the forms of fome antique vafes, or in other works of the pencil or the chiflel, we feel a general glow of d(elight, which feems to influence all our fenfes ; and, if the objecl: be not too large, we experience an attraction to embrace it with our arms, and to falute it with our lips, as we did in our early infancy the bofom of our mother. And thus we find, according to the ingenious idea of Hogarth, that the waving lines of beauty were ori- ginally taken from the temple of Venus. This animal attraction is love; which is a fenfa- tion, when the object is prefent ; and a defire, when it is abfent. Which conftitutes-the pureft fource of human felicity, the cordial drop in the otherwife vapid cup of life, and which overpays mankind for the care and labour, which are attached to the pre- eminence of his fituation above other animals. It mould have been obferved, that colour as well as form fometimes enters into our idea of a beauti- ful object, as a good complexion for inftance, be- caufe a fine or fair colour is in general a fign of health, and conveys to us an idea of the warmth of the object i and a pale countenance on the contrary gives an idea of its being cold to the touch. It was before remarked, that young animals ufe their lips to diftinguifh the forms of things, as well as SicT.XVI. 7. OF INSTINCT. i7s as their fingers, and hence we learn the origin of our inclination to faiute beautiful objects with our lips. For a definition of Grace, fee Clafs III. i. 2. 4, VII. There are two ways by which we become acquainted with the paiiions of others: fir ft, by having obferved the effects of them, as of fear or anger, on our own bodies, v, e know at fight when others are under the influence of thefe affections. So when two cocks are preparing to light, each feels the feathers rife round his own neck, and knows from the fame fign the difpofition of his adverfary; and children long before they can fpeak, or under- ftand the language of their parents, may be fright- ened by an angry countenance, or foothed by fmiles and blandiflimcnts. Secondly, when we put ourfelves into the atti- tude ihat any paflion naturally occafions, we foon in fome degree acquire that paffion ; hence when thofe that icold indulge themfdves in loud oaths, and violent actions of the arms, they incu.afe their anger by the mode of exprefling' themlelvts : and on the contrary the counterfeited f njle of pleafure in difagreeable company foon brings along with it a portion of the reality, as is well iliuff rated by Mr. Burke, (flay on the Sublime and Beautiful.) This latter method of entering into the paflions of others is rendered of very extenfive ufe by the pleafure we take in imitation, which js every day prefented before our eyes, in the actions of 'chil- dren, and ind.ed in all the cuftoms and fafliions of the world. From this our aptitude to imitation, arifes what is generally underflood by the word fympathy fo well explained by. Dr. Smith of Glaf- gow. Thus the appearance of a cheerful counte- nance gives us pleafure, and oi a melancholy one makes us iorrowful. .vning and fom. and only howl, like the dogs that are natives of that eoaft, (World Difplayed, Vol. XVII. p. 26.) A circumftance not diffimilar to this, and equally curious, is mentioned by Kircherus, de Mufurgia, in, his Chapter de Lulciniis, " That the young nightingales that are hatched under other birds, never fing till they are inftru&ed by the company of other nightingales." And Johnfton affirms, that the night- ingales that vifit Scotland, have not thefame harmony as thole of Italy, (Pennant's Zoology, octavo, p. 255) ; xvhich would lead us to fufpecl that the. fmging of birds, like human mufic, is an artificial language, rather than a natural expreflion of paflion. X. Our mufic like our language, is perhaps en- tirely conflituted of artificial tones, which by habit fugged certain agreeable paflions. For the fame combination of notes and tones do not excite devotion, love, or poetic melancholy in a native of Indoftan and of Europe. And £C the Highlander has the lame warlike ideas annexed to the found of a bag- pipe (an instrument which an Englilhman derides;, as the Englifhman has to that of a trumpet or fife,*' (Dr. Brown's Union of Poetry and Mufic, p. 58.) So " the mufic of the Turks is very different from the Italian, and the people of Fez and Morocco have again a different kind, which to us appears very rough vaud horrid, but is highly pleafing to them,'* (L* Arte Armoniaca a Giorgio Antoniotto). Hence we fee why the Italian opera does not delight an un- tutored Englifhman; and why thofe, who are unac- cu domed to mufic, are more pleafed with a tune, the Second or third time they hear it, than the firft. For then the fame melodious train of founds excites the melancholy, they had learned from the fong ; or the lame vivid combination of them recalls all the ininhful ideas of the dance and company. Even the founds, that were once difagreeable to us, may by habit be affociated with other ideas, fo as to become SKCT. XVI. ic. OF INSTINCT. 185 become agreeable. Father Lafitau, in his account of the Iroquois, fays " the mufic and dance of thofe Americans, have fomething in them extremely bar- barous, which at firft difgufts. We grow reconciled to them by degrees, and in the end partake of them with pleafure, the favages themfelves are fond of them to diftra&ion," (IV:ceurs des Savages, Tom. ii.) There are indeed a few founds, that we very ge- nerally afibciate with agreeable ideas, as the whitt- ling of birds, or purring of animals, that are de- lighted ; and fome others, that we as generally affo- ciate with difagreeable ideas, as the cries of animals in pain, the hifs of forne of them in anger, and the midnight howl of beads of prey. Yet we receive no terrible or fublime ideas from the lowing of a cow, or the braying of an afs. Which evinces, that thefe emotions are owing to previous aflbciations. So if the rumbling of a carriage in the llreet be for a mo- ment miftaken for thunder, we receive a fublime fen- fation, which ceafes as foon as foon as we know it is the noife of a coach and fix. There are other difagreeable founds, that are faid to fet the teeth on edge ; which, as they have always been thought a neceflary effect of certain difcor- dant notes, become a proper fubjecl: of our inquiry. Every one in his childhood has repeatedly bit a part of the glafs or earthen veflel, in which his food has been given him, and has thence had a very difagree- able fenfatiori in the teeth, which fenfation was de- figned by nature to prevent us from exerting them on objects harder than themfelves. The jarring found produced between the cup and the teeth is al- ways attendant on this difagreeable fenfation : and ever after when fuch a found is accidentally produ- ced by the conflicl of two hard bodies, we feel by aflociation of ideas the concomitant dif.igueable fen- fation in our teeth. Others »86 OF INSTINCT. SECT. XVI. 10. Others have in their infancy frequently held the corner of a filk handkerchief in their mouth, or the end of the velvet cape of their coat, whilft their companions in play have plucked it from them, and have given another diiagreeable fenfation to their teeth, which has afterwards recurred on touching thofe materials. And the fight of a knife drawn along a china plate, though no found is excited by it, and even the imagination of fuch a knife and plate fo fcraped together, I know by repeated ex- perience will produce the fame difagreeable fenfa- tion of the teeth. Thefe circumnances indifputably prove, that this fenfation of the tooth-edge is owing to aflbciated ideas ; as it is equally excitable by fight, touch, hearing, or imagination. In refpect to the artificial proportions of found excited by mufical inftruments, thofe, who have early in life aflbciated them with agreeable ideas, and have nicely attended to diftinguim them from each other, are faid to have a good ear, in that coun- try where fuch proportions are in famion : and not from any fuperior perfection in the organ of hearing, or any inftinftive fympathy between certain founds and pafiions. 1 have obferved a child to be exquifitely delighted with muiic, and who could with great facility learn to fmg any tune that he heard diftinctly, and yet whole organ of hearing was fo imperfect, that it was neceflary to fpeak louder to him in common con- verfation than to others. Our mufic, like our architecture, feems to have no foundation in nature, they are both arts purely of human creation, as they imitate nothing. And the profeffors of them have only clafled thofe circum- liances, that are mod agreeable to the accidental rafle of their age, or country ; and have called it Proportion* But this proportion mud always fluc- tuate. SECT. XVI. ii. OF INSTINCT. 187 tuate, as it refts on the caprices, that are introdu- ced into our minds by our various modes of educa- tion. And thefe fluctuations of tafte mud become more frequent in the prefent age, where mankind have enfranchifed themfelves from the blind obedi- ence to the rules of antiquity in perhaps every fcience, but that of architecture. See Seel. XII. 7- 1- XL There are many articles of knowledge, which the animals in cultivated countries feem to learn very early in their lives, either from each other, or from experience, or observation : one of the mod general of thefe is to avoid mankind. There is fo great a refemblancc in the natural language of the paflions of all animals, that we generally know, when they are in a pacific, or in a malevolent hu- mour, they have the fame knowledge of us ; and hence we can fcold them from us by fome tones and geftures, and could poflibly attract them to us by others, if they were not already apprized of our ge- neral malevolence towards them. Mr. Gmelin, Profeflbr at Peterfburg, allures us, that in his jour- ney into Siberia, undertaken by order of the Em- prefs of Ruflia, he faw foxes, that exprefled no fear of himfelf or companions, but permitted him to come quite near them^ having never feen the human creature before. And Mr. Bougainville relates, that at his arrival at the Malouine, or Falkland's Iflands, which were not inhabited by men, all the animals came about himfelf and his people ; the fowls fettling upon their heads and fhoulders, and the quadrupeds running about their feet. From the difficulty of acquiring the confidence of old animals, and the eafe of taming young ones, it appears that the fear, they all conceive at the fight of mankind, is an acquired article of knowledge. This knowledge is more nicely underftood by rooks, who are formed into fodeties, and build, as O it i88 OF INSTINCT. it were, cities over our heads; they evidently dif- tinguifli, that the danger is greater when a man is armed with a gun. Every one has feen this, who in the fpring of the year has walked under a rookery with a gun in his hand : the inhabitants of the trees rife on their wings, and feream to the unfledged young to flirink into their nefts from the fight of the enemy. The vulgar obferving this circumftance fo uniformly to occur, aflert that rooks can fmell gun-powder. The fieldfairs, (turdus pilarus) which breed in Norway, and come hither in the cold feafon for our winter berries ; as they are affociated in flocks, and are in a foreign country, have evident marks of keeping a kind of watch, to remark and announce the appearance of danger. On approaching a tree, that is covered with them, they continue fearlefs till one at the extremity of the bum rifing on his \vings gives a loud and peculiar note of alarm, when they all immediately fly, except one other, who continues till you approach flill nearer, to certify as it were the reality of the danger, and then he alfo flies off repeating the note of alarm. And in the woods about Senegal there is- a bird called uett-uett by the negroes, andfquallers by the French, which, as foon as they fee a man, fet up a, loud feream, and keep flying round him, asif their intent was to warn other birds, which uponhearing the cry immediately take wing. Thefe birds are the bane of fportfmen,. and frequently put me into a paffion, and obliged me to (hoot them (Adanfon's Voyage to Senegal, 78). For the fame intent the letter birds' of our climate feem to fly after a hawk, cuckooy or owl, and feream to prevent their com- panions from being furprifed by the general enemies of themfelves, or of their eggs and progeny. But the lapwing, (charadrius pluvialis Lin.) when her unfledged offspring run about the marfhes, where SiiCT.XVL ii. OF INSTINCT. 189 where they were hatched, not only gives the note of alarm at the approach of men or dogs, that her young may conceal themfelves ; but flying and fcreaming near the adverfary, (he appears more foli- citous and impatient, as he recedes from her family, and thus endeavours to miflead him, and frequently fucceeds in her defign. Thefe laft inftances are fo appofite to the fituation, rather than to the natures of the creatures, that ufe them ; and are fo fimilar to the actions of men in the fame circumftances, that we cannot but believe, that they proceed from a fimilar principle. Mifs M. E. Jacfon acquainted me, that (he wit- nefled this autumn an agreeable inftance of fagacity in a little bird, which feemed to ufe the means to obtain an end ; the bird repeatedly hopped upon a poppy-ftem, and (hook the head with its bill, till many feeds were fcattered, then it fettled on the ground, and eat the feeds, and again repeated the lame management. Sept. i, i794._ On the northern coaft of Ireland a friend of mine faw above a hundred crows at once preying upon mufcles ; each crow took a mufcle up into the air twenty or forty yards high, and let it fall on the (tones, and thus by breaking the (hell, got poflef- fion of the animal. — A certain philofopher (I think it was Anaxagoras) walking along the fea-fhore to gather (hells, one of thefe unlucky birds mistaking his bald head for a (lone, dropped a (hell-filh upon it, and killed at once a philofopher and an oyfter. Our domeftic animals, that have fome liberty, are alfo pofleffed of fome peculiar traditional knowledge; dogs and cats have been forced into .each other's fo- ciety, though naturally animals of a very different kind, and have hence learned from each other to eat dog's grafs, (agroitis canina) when they are fick, to promote vomiting. I have feen a cat miftake the O 2, blade 490 OF INSTINCT. SECT. XVI. n. blade of barley for this grafs, which evinces it is an acquired knowledge. They have alfo learnt of each other to cover their excrement and urine ; about a fpoonful of water was fpilt upon iny hearth from the tea-kettle, and I obferved a kitten cover it with aflies. Hence this mud alfo be an acquired art, as the crea- ture miflook the application of it. To preferve their fur clean, and efpecially their \vhiikers, cats warn their faces, and generally quite behind their ears, every time they eat. As they cannot lick thofe places with their tongues, they firit wet the infide of the leg with faliva, and then re- peatedly warn their faces with it, which mufl origi- nally be an effect of reafoning, becaufe a means is ufed to produce an effect ; and feems afterwards to be taught or acquired by imitation, like the greateft part of human arts* Thefe animals feem to poiTefs fomething like an additional fenfe by means of their whifkers ; which have perhaps fome analogy to the antennas of moths and butterflies. The whifkers of cats confift not only of the long hairs on their upper lips, but they have alfo four or five long hairs (landing up from each eyebrow, and alfo two or three on each cheek ; all which, when the animal erects them, make with their points fo many parts of the periphery of a cir- cle, of an extent at lead equal to the circumference of any part of their own bodies. With this inflru- ment, I conceive, by a little experience, they can at price determine, whether any aperture amongft hedges or fhrubs, in which animals of this genus live in their wild flare, is large enough to admit their bodies ; which to them is a matter of the great- eft confequence, whether purfuing or purfued. They have like wife a power of erecting and bring- ing forward the whifkers on their lips ; which pro- . bably is for the purpofe of feeling, whether a dark hole be further- permeable. The SECT. XVI. ii. OF INSTINCT. 191 The antennas, or horns, of butterflies and moths, who have awkward wings, the minute feathers of which are very liable to injury, ferve, I fuppofe, a fimilar purpofe of meafuring, as they fly or creep amongft the leaves of plants or trees, whither their wings can pafs without touching them. Mr. Leonard, a very intelligent friend of mine, faw a cat catch a trout by darting upon it in a deep clear water at the mill at Weaford, near Lichfield. The cat belonged to Mr. Stanley, who had often feen her catch fifh in the fame manner in fummer, when the mill-pool was drawu fo low, that the fifti could be feen. I have heard of other cats taking fifh in mallow water, as they flood on the bank. This feems a natural art of taking their prey in cats, which their acquired delicacy by domeftication has in general prevented them from ufing, though their defire of eating fifh continues in its original ftrength. Mr. White, in his ingenious Hiftory of Selbourn, was witnefs to a cat's fuckling a young hare, which followed her about the garden, and came jumping to her call of affection. At Elford near Lichfield, the Rev. Mr. Sawley had taken the young ones out of a hare, which was fhot ; they were alive, and the cat, who had juft lofl her own kittens, carried them away, as it was fuppofed, to eat them ; but it pre- fently appeared, that it was affection not hunger which incited her, as fhe fuckled them, and brought them up as their mother. Other inflances of the miftaken application of what has been termed indinct may be obferved in flies in the night, who miftaking a candle for day* light, approach and perifh in the flame. So the pu- trid fmell of the flapelia, or carrion-flqwer, allures the large flefh-fly to depofit its young worms on its beautiful petals, which perifh there for want of ftourifhment. This therefore cannot be a necefTary inftinft 192 OF INSTINCT. SECT. XVI. ir inflincl, becaufe the creature miftakes the applica- tion of it. Though in this country horfes fhew little veftiges of policy, yet in the defarts of Tartary, and Siberia, when hunted by the Tartars they are feen to form a kind of community, fet watches to prevent their being furprifed, and have commanders, who direct, and haften their flight, Origin of Language, Vol. I. p. 2 i 2. In this country, where four or five horfes travel in a line, the firft always points his ears for- ward, and the lad points his backward, while the intermediate ones leem quite carelefs in this refpe£t; which feems a part of policy to prevent furprife. As all animals depend moft on the ear to apprize them of the approach of danger, the eye taking in only half the horizon at once, and horfes poflefs a great nicety of this fenfe ; as appears from their mode of fighting mentioned No. 8. 5. of this Section, as well as by common obfervation. There are fome parts of a horfe, which he cannot conveniently rub, when they itch, as about the fhoulder, which he can neither bite with his teeth, nor fcratch with his hind fool ; when this part itches, he goes to another horfe, and gently bites him in the part which he wifhes to be bitten, which is im* mediately done by his intelligent friend. I once observed a young foal thus bite its large mother, who did not choofe to drop the grafs fhe had in her mouth, and rubbed her nofe againfl the foal's neck initead of biting it ; which evinces that fhe knew the defign of her progeny, and was not governed by a necefiary inftind to bite where fhe was bitten, Many of our fhrubs, which would otherwife af- ford an agreeable food to horfes, are armed with thorns or prickles, which fecure them from thofe animals; as the holly, hawthorn, goofeberry, gorfe. In the extenfive moorlands of Staftbrdfhire, the horfe§ Sacr.XVI. n. OF INSTINCT. 193 horfes have learnt to (tamp upon a gorfe-bufh with one of their fore-feet for a minute together, and when the points are broken, they eat it without injury. The horfes in the new for eft in Hampihire are affirmed to do the fame by Mr. Gilpin. Foreft Scenery, II. 251, and 112. Which is an art other horfes in the fertile parts of the country do not pofiefs, and prick their months till they bleed, if they are induced by hunger or caprice to attempt eating gorfe. Swine have a fenfe of touch as well as of fmell at the end of their nofe, which they ufe as a hand, both to root up the foil, and to turn over and exa- mine objects of food, fomewhat like the probofcis of an elephant. As they require flicker from the cold in this climate, they have learnt to collecl; draw in theh mouths to make their neft, when the wind blows cold ; and to call their companions by repeated cries to aflift in the work, and add to their warmth by. their numerous bed-fellows. Hence thefe animals, which are efteemed fo unclean, have alfo learned never to befoul their dens, where they have liberty, with their own excrement ; an art, which cows and horfes, which have open hovels to run into, have never acquired. I have obferved great fagacky in fwine ; but the fhort lives we allow them, and their general confinement, prevents their improvement, which might probably be otherwife greater than that of dogs. Inftances of the fagacity and knowledge of ani- mals are very numerous to every obferver, and their docility in learning various arts from mankind, evinces that they may learn fimilar arts from their own fpecies, and thus be pofleffed of much acquired and traditional knowledge. A dog whofe natural prey is flieep, is taught by mankind, not only to leave them unmolefted, but to 194- OF INSTINCT. SECT.XVI.M, to guard them ; and to hunt, to fet, or to deftroy other kinds of animals, as birds, or vermin ; and in fome countries to catch fi(h, in others to find truffles, and to pra&ife a great variety of tricks ; is it more furprifing that the crows mould teach each other, that the hawk can catch lefs birds, by the fuperior fwiftnefs of his wing, and if two of them follow him, till he fucceeds in his defign, that they can by force mare a part of the capture ? This 1 have formerly obferved with attention and afto- nifhment. There is one kind of pelican mentioned by Mr. Ofbeck, one of Linnseus's travelling pupils (the pelicanus aquilus), whofe food is fim ; and which it takes from other birds, becaufe it is. not formed to catch them itfelf ; hence it is called by the Eng- Jim a Man-of-war-bird, Voyage to China, p. 88. There are many other interefting anecdotes of the pelican and cormorant, collected from authors of the beft authority, in a well-managed Natural Hif- tory for Children, publifhed by Mr. Galton. John- fon. London. And the following narration from the very accu- rate Monf. Adanfon, in his Voyage to Senegal, may gain credit with the reader : as his employ- ment in this country was folely to make obferva- tions in natural hiftory. On the river Niger, in his road to the ifland Griel, he faw a great number pf pelicans, or wide throats. " They moved with great ftate like fwans upon the water, and are the largeft bird next to the oftrich ; the bill of the one I killed was upwards of a foot and half long, and the bag fattened underneath it held two and twenty pints of water. They fwim in flocks, and form a large circle, which they contract afterwards, driv- Jng.the fim before them with their legs : when they fee the fifh in fufficient number confined in this fpace. SECT. XVI. 12. OF INSTINCT, 195 fpace, they plunge their bill wide open into the water, and (hut it again with great quicknefs. They thus get fifh into their throat-bag, which they eat afterwards on ihore at their leifure." P. 247. XII. 'Ihe knowledge and language of thofe birds, that frequently change their climate with the fea- fons, is fHll- more extenfive : as they perform thefe migrations in large focieties, and are Ids fubjecl to the power of man, than the refident tribes of birds. They are faid to follow a leader during the day, who is occafionally changed, and to keep a conti- nual cry during the night to keep themfelves toge- ther. It is probable that thefe emigrations were at firft undertaken as accident directed, by the more adventurous of their fpecies, and learned from one another like the difcoveries of mankind in naviga- tion. The following circumltances ftrongly fupport this opinion. i. Nature has provided thefe animals, in the cli- mates where they are produced, with another re- fource : when the feafon becomes too cold for their constitutions, or the food they were fupported with ceafes to be fupplied, I mean that of ileeping, Dormice, fnakes, and bats, have not the means of changing their country ; the two former from the want of wings, and the latter from his being not able to bear the light of the day. Hence thefe ani- mals are obliged to make ufe of this refource, and lleep during the winter. And thofe fwallows that have been hatched too late in the year to acquire their full (Irength of pinion, or that have been maimed by accident of difeafe, have been frequent- ly found in the hollows of rocks on the fea coafts, and even under water in this torpid ftate, from which they have been revived by the warmth of a fire. This torpid date of fwallows is teftined by innumerable evidences both of antient and modern names. *96 OFINSTINCT. SECT. XVf. 12. names. Ariftotle -fpeaking of the fwallows fays, " They pafs into warmer climates in winter, if fuch places are at no great diftance ; if they are, they bury themfelves in .the climates where they dwell," (8. Hift. c. 16. See alfo Derham's Phyf. Theol. v. ii. p. 177.) Hence their emigrations cannot depend on a necejjary inftincl:, asr the emigrations themfelves are not mceffary ! 2. When the weather becomes cold, the fwal- lows in the neighbourhood aifemble in large flocks ; that is, the unexperienced attend thofe that have before experienced the journey they are about to undertake : they are then feen fame times to hover on the coaft, till there is calm weather, or a wind, that fuits the direction of their flight, Other birds of paflage have been drowned by thoufands in the fea, or have fettled on (hips quite exhaufted with fatigue. And others, either by miftaking their courfe, or by diftrefs of weather, have arrived in countries where they were never feen before, and thus are evidently fubjec~l tto the fame hazards that the human fpecies undergo, in the execution of their artificial purpofes. 3. The fame birds are emigrant from fome coun- tries and not fo from others : the fwallows were feen at Goree in January by an ingenious philofopher of my acquaintance, and he was told that they conti- nued there all the year; as the warmth of the cli- mate was at all feafons fufficient for their own con- flituiions, and for the production of the flies that fupply them with nouriftiment. Herodotus fays, that in Lybia, about the fprings of the Nile, tbe fwallows continue all the year. (L. 2,) Quails (tetrao corturnix, Lin.) are birds of paflage from the coalt of Barbary to Italy, and have fre- quently fettled in large fhoals on (hips, fatigued with their flight. (Hay, Wifdom of God, p. 129. Derharu SECT. XVI. 12. O F ! N S 7 I N C T. 197 Derham Phyfic. Theol. v. ii. p. 178.) Dr. Ruffe!, in his Hiftory of Aleppo, obferves that the fwallows vifit that country about the end of February, and having hatched their young difappear about the end of July ; and returning again about the beginning of October, continue about a fortnight, and then again difappear. (P. 70 ) When my late friend Dr. Chambres, of Derby, was on the ifland of Caprea in the bay of Naples, he was informed that great flights of quails annu- ally fettle on that ifland about the beginning of May, in their paffage from Africa to Europe. And that they always come when the fouth-eaft wind blows, are fatigued when they reft on this iiland, and are taken in fuch amazing quantities and fold to the Continent, that the inhabitants pay the bifhop his ftipend out of the profits arifmg from the fale of them. The flights of thefe birds acrofs the Mediterra- nean are recorded near three thoufand years ago. " There went forth a wind from the Loid and brought quails from the fea, and let them fall upon the camp, a day's journey round about it, and they were two cubits above the earth," (Numbers, chap, ii. ver. 31.) In our country, Mr. Pennant informs us, that fome quails migrate, and others only remove from the internal parts of the ifland to the coafts, (Zoo- logy, octavo, 210.) Some of the ringdoves and flares breed here, others migrate, (ibid. 510, 511.^ And the flender billed fmall birds do not all quit thefe kingdoms in the winter, though the difficulty of procuring the worms and infects, that they feed on, fupplies the fame reafon for migration to them all, (ibid. 51 1.) Linnseus has obferved, that in Sweden the female chaffinches quit that country in September, migrat- ing into Holland, and leave their mates behind till their i^S O F I N S T I N C T. SECT. XVI. 12. their return in fpring. Hence he has called them Fringilla ccelebs, (Amaen. Acad. ii. 42. iv. 595.) Now in our climate both fexes of them are peren- nial birds. And Mr. Pennant obferves that the hoo- poe, chatterer, hawfinch, arid crofsbill, migrate into England fo rarely, and at fuch uncertain times, as not to deferve to be ranked among our birds of paf- fage, (ibid. 51'!.) The waterfowl, as geefe and ducks, are better adapted for long migrations, than the other tribes of birds, as, when the weather is calm, they can not only reft ttiemfelyes, or fleep upon the ocean, but poflibly procure fome kind of food from it. Hence in Siberia, as foon as the lakes are fro- zen, the water fowl, which are very numerous, all difappear, ,and are fuppofed to fly to warmer cli- mates, except the rail, which, from its inability for long flights, probably fleeps, like our bat, in their winter. The following account from the Journey of ProfefTor Gmelin, may entertain the reader, " In the neighbourhood of Krafnoiark, amongft many other emigrant water fowls, we obferved a great number of rails, which when purfued never took flight, but endeavoured to efcape by running. We enquired how thefe birds, that could not fly, could retire into other countries in the winter, and were told, vbo-th by the Tartars and Affanians, that they well knew thofe birds could not alone pafs into other countries : but when the cranes (|es grues) retire in autumn, each one takes a rail (un rale; upon, his back, and carries hirn to a warmer climate.'* Recapitulation. T. All birds of paflfage can exift in the climates, where they are produced. a, They SECT. XVI. 13. O F I N S T I N C T. 199 2. They are fubjeft in their migrations to the fame accidents and difficulties, that mankind are fubjecl: to in navigation. 3. The fame fpecies of birds migrate from fome countries, and are refident in others. From all thefe circumftances it appears that the migrations of birds are not produced by a necef- fary inftincl:, but are accidental improvements, like the arts among mankind, taught by their cotempo- raries, or delivered by tradition from one genera- tion of them to another. XIII. In the feafon of the year which fupplies the nourimment proper for the expected brood, the birds enter into a contract of marriage, and with joint labour conftruct a bed for the reception of their offspring. Their choice of the proper feafon, their contracts of marriage, and the regularity with which they conftrudt their nefts, have in all ages excited the admiration of naturalifts ; and have always been attributed to the power of in- fHnft, which, like the occult qualities of the an- tient philofophers, prevented all further enquiry. We (hall confider them in their order. Their Choice of the Seafon. Our domeftic birds, that are plentifully fupplied throughout the year with their adapted food, and are covered with houfes from the inrlemeacy of the weather, lay their eggs at any feafon: which evinces that the fpring of the year is not pointed out to them by a necelfary inftincl. Whilft the wild tribes of birds choofe this time of the year from their acquired knowledge, that the mild temperature of the air is more convenient for hatching their eggs, and is foon likely to fupply . that O F I N S T I N C T. $ECT. XVI. i 3. that kind of nourifhment that is wanted for their young. If the genial warmth of the fpring produced the paffion of love, as it expands the foliage of trees, all other animals (hould feel its influence as well as birds : but, the viviparous creatures, as they fuckle their young, that is, as they previoufly di- geft the natural food, that it .may better fuit the tender flomachs of their offspring, experience the influence of this paflion at all feafons of the year, as cats and bitches. The graminivorous animals indeed generally produce their young about the time when grafs is fupplied in the greateft plenty, but this is without any degree of exaclnefs^ as ap- pears from our cows, fheep, ,and hares, and may be a part of the traditional knowledge, which they learn from the example of the parents. fbeir Contrafts of Marriage. Their mutual paffion, and the acqnired know- ledge, that their joint labour is neceflary to procure fuftenance for their numerous family, induces the wild birds to enter into a contract of marriage, which does not however take place among the ducks, geefe, and fowls, that are provided with their daily food from our barns. An ingenious philofopher has lately denied, that animals can enter into contracts, and thinks this an efTential difference between them and the human creature : — but does not daily obfervation con- vince us, that they form contracts of friendfhip with each other, and with mankind ? When pup- pies and kittens play together, is there not a tacit contract, that they will not hurt each other ? And does not your favorite dog expect you mould give him his daily food, for his fervices and attention to SECT. XVI. 13. OF INSTINCT. 201 to you ? And thus barters his love for your pro. tection ? In the fame manner that all contrads arc made amongft men, that do not underftand each others' arbitrary language. The Conjlruftion of their Ne/ls. 1. They feem to be inftrufted how to build their nefts from their obfervation of that, in which they were educated, and from their knowledge of thofe things, that are mod agreeable to their touch in refped to warmth, cleanlinefs, and (lability. They choofe their fituations from their ideas of fafety from their enemies., and of flicker from the wea- ther. Nor is the colour of their nefts a circum- ftance unthought of; the finches, that build in green hedges, cover their habitations with green mofs ; the fwallow or martin, that builds againft rocks and houfes, covers her's with clay, whilfi the lark choofes vegetable ftraw nearly of the co- lour of the ground (lie inhabits : by this contrivance, they are all lefs liable1 to be difcovered by their ad- verlaries. 2. Nor are the nefts of the fame fpecies of birds conftrucled always of the fame materials, nor in the fame form ; which is another circumftance that afcertains, that they are led by obfervation. In the trees before Mr. Levet's houfe in Lichfield, there are annually nefts built by fparrows, a bird which ufually builds under the tiles of houfes, or the thatch of barns. Not finding fuch convenient fituations for iheir nefts, they build a covered neft bigger than a man's head, with an opening like a mouth at the fide, refembling that of a magpie, except that it is built with ftraw and iay, and lined with feathers, and fo nicely managed as to be a de- fence againft both wind and rain. The sea O F I N S T I N C T. SECT. XVL I ji The following extract from a Letter of the Rev. IVJr. J. Darwin, of Carleton Scroop in Lincolnfhire, authenticates a curious fact of this kind. " When I mentioned to you the circumftance of crows or frooks building in the fpire of Welbourn church, you expreiTed a defire of being well informed of the certainty of the fact. Welbourn is fituated in the road from Grantham to Lincoln on the Cliff row ; I yefterday took a ride thither, and enquired of the re&or, Mr. Ridgehill, whether the report was true, that rooks built in the fpire of his church. He af- fured me it was true, and that they had done fo time immemorial, as his parifhioners affirmed. There was a common tradition, he faid, that formerly a rookery in fome high trees adjoined the church yard, which being cut down (probably in the ipring, the building ieafon), the rooks removed to the church, and built theiy nefts on the outfide of the fpire on the tops of •windows, which by their projection a little from the fpire made them convenient room, but that they built a Ho on the infide. I faw two nefts made with /licks on the outfide, and in the fpires, and Mr. Ridgehill faid there were always a great many. Ct Ifpent the day with Mr. Wright, a clergyman, at Fulbeck, near Welbourn, and in the afternoon Dr. Ellis of Headenham, about two miles from Weibourn, drank tea at Mr. Wright's, who faid he remembered, when Mr. Welby lived at Welbourn, that he received a letter from an acquaintance in the weft of England, defiring an anfwer, whether the report of rooks building in Welbourn church was true, as a wager was depending on that fubject : to which he returned an anfwer ascertaining the fact, and decided the wager." Aug. 30, 1704. So the jackdaw (corvus monedula) generally builds in church-fteeples, or under the roofs of high houfes ; but at Selbourn, in Southamptonihire, where towers and fteeples are not fufficiently nu- merous, Skcr. XVI. 13. OFlNSTINct. merous, thefe birds build in forfaken rabbit bur- rows. See a curious account of thefe fubterra- nean nefts in White's Hiftory of Selbourn, p. 59. Can the ikilful change of architecture in thefe birds and the fparrows above mentioned be go- verned by inftinct ? Then they muft have two in- ftincts, one for common, and the other for extra- ordinary occafions. I have feen green worded in a neft, which no where exifts in nature : and the down of thirties irt thofe nefts, that were by fome accident conftructed later in the fummer, which material could not be procured for the earlier nefts : in many different climates they cannot procure the fame materials^ that they ufe in ours. And it is well known, that the canary birds, that are propagated in this coun- try, and the finches, that are kept tame, will build their nefts of any flexile materials, that are given them. Plutarch, in his Book on Rivers, fpeaking of the Nile, fays* " that the fwallows collect a ma- terial, when the waters recede, with which they form nefts, that are impervious to water." And in India there is a fwallow that collects a glutinous fubftance for this purpofe, whofe neft is efculent, and efteemed a principal rarity amongft epicures, (Lin. Syft. Nat.) Both thefe muft be conftruded of very different materials from thofe ufed by the fwal- lows of our country. In India the birds exert more artifice in building their nefts on account of the monkeys and fnakes : fome form their penfile nefts in the fliape of a purfe, deep and open at top; others with a hole in the fide ; and others, ftill more cautious, with an en- trance at the very bottom, forming their lodge near the fummit. But the taylor-bird will not ever truft its neft to the extremity of a, tender twig, but makes one more advance to fafety by fixing it to the leaf itfelf. It picks up a dead leaf, and fews VOL. I, P i f 04 O F I N S T I N C T. SECT. XVI. i> it to the fide of a living one, its flender bill being its needle, and its thread fome fine fibres ; the lin- ing confifts of feathers, gofTamer, and down; iu eggs are white, the colour of the bird light yellow, its length three inches, its weight three ftxteenths of an ounce ; fo that the materials of the neft, and the weight of the bird, are not likely to draw down an habitation fo flightly fufpended. A neft of this, bird is preferved in the Bririfh Mufeum, (Pennant** Indian Zoology). This calls te* one's mind the Mo- faic account of the origin of mankind, the firft dawning of art there afcribed to rhemr i^that of fewing leaves together. For many other curious kinds of nefts fee Natural Hiftory for Children, by Mr. Galton. Johnfon. London Part I. p. 47* Gen. Oriolus* 3, Thofe birds that are brought up by our care* and have had little communication with others of their own fpecies, are very defective in this ac- quired knowledge ; they are not only very awk^ ward in the conftrucUon of their nefts, but gene- rally fcatter their eggs in various parts of the room or cage, where they are confined, and feldom pro- duce young ones, till, by failing in their firft at- tempt, they have learnt fomsthing from their owrv obfervation. 4. During the time of incubation birds are faid' in general to turn their eggs every day ; fome cover them, when they leave the neft, as^ ducks and' geefe.; in fome the male is^faid to bring food to the female, that (he may have lefs occafion of abfencer m others he is faid to take her place, when (he goes in queft, of food -r and all of rhem are faid to kave their eggs a fhorter time in- cold weather than in warm. In. Senegal' the oftrich fits on her eggs only during the night, leaving them in the day to thq, heat of the fun ; but at the Cape of Good Hope, where the heat is lefs,, fh$ fits on them day and night. If . XVI. 13- OF INSTINCT. 205 If it fhould be afked, what induces a bird to fit weeks on its firft eggs unconfcious that a brood of young ones will be the product ? The anfwer mud be, that it is the fame paflion that induces the hu- man mother to hold her offspring whole nights and days in her fond arms, and prefs it to her bofom^ unconfcious of its future growth to fenfe and man- hood, till obfervation. or tradition have informed her. 5. And as many ladies are too refined to hurfe their own children, and deliver them to the care and provifion of others ; fo is there one inftance of this vice in the feathered world. The cuckoo in fome parts of England, as I am well informed by a very diftinft and ingenious gentleman, hatches and educates her own young ; whilft in other parts me builds no neft, but ufes that of fome leffer bird, generally either of the wagtail, or hedge fparrow, and depofiting one egg in it, takes no further care of her progeny. As the Rev, Mr. Stafford was walking in Glofop Dale, in the Peak of Derbyfhire, he faw a cuckoo rife from its neft. Thfe neft was on the ftump of a tree, that had been fome time felled, among fome chips that were in part turned grey^ fo as much to referable the colour of the birdj in this neft were two young cuckoos : tying a firing about the leg of one of them^ he pegged the other end of it to the ground, and very frequently for many days beheld the old cuckoo feed thef£ her young, as he flood Very near them. The following extract of a Letter from the Rev. Mr. Wilmot, of Morley, near Derby, ftrengthens the truth of the fact above mentioned, of the cuckoo fometimes making a neft, and hatching her own young. f birds, their patient incubation, and the art of the cuckoo in depofiting her egg in her neighbour's jmrfery, are inftances of great fagacity in thole creatures : and yet they are much inferior to the arts exerted by many of the infe6t tribes on fimilar occafions. The hairy excrefcences on briars, the oak apples, the blafted leaves of trees, and the lumps on the backs of cows, are fituations that are rather produced than, chofen by the mother in- fed for the convenience of her offspring. The cells of bees, waips, fpiders, and of the various coralline infects, equally aftonim us, whether we attend to the materials or to the architecture. But the conduct of the ant, and of iorne fpecies of the ichneumon fly in the incubation of their eggs, is equal to any exertion of human fcicnce. The ants' many times in a day move their eggs Dearer the furface of their habitation, or deeper be* low it, as the heat of the weather varies ; and ia colder days lie upon them in heaps for the purpofe of incubation ; if their manfion is too dry, they carry them to places where there is moifture, and you may diftinclly fee the little worms move and £ick up the water. When too much moifture ap- proaches their neft, they convey their eggs deeper in the earth, or to fome other place of fafety, (Swammerd. Epil. ad Hift. Infects, p. 153. Phil, Jranf. No. 23. Lowthorp, V. 2. p. 7.) There is one fpecies of ichneumon-fly, that digs a hole in the earth, and carrying into it two or three living caterpillars, depofits her eggs, and nicely clofing up the neft leaves them there ; partly doubt- lefs to ajlift the incubation, and partly to fupply food IBBCT.XVI.i6. OF INSTINCT. 213 food to her future young, (Derham. B. 4. c. 13, Arift-.>tlc Hift. Animal, L. 5. c. 20. V A friend of mine put about fifty large caterpil- lars collected fro HI cabbages on iome bran and a few leaves Litt.. a. box, and covered it with gauze to p. event dieir elcape. After a few days we law, from moix rvm three: fourths of them, about eight or ten Htri, aterpillars of the ichneumon-fly come out of the-.r backs, arid Jpni coch a fmall cocoon of filk, ai. ' in a few days the large caterpillars died. This fruail fly it feems lavs it$ egg in the back of the cabbage caterpillar, which when hatched preys u; >n 'he material, which is produced there for the purpose of irrakin- filk for the future neft of the cabbage caterpillar; of which being deprived, the cr.amre wa'nders about till it dies, and thus our gardens are preferred by the ingenuity of this cruel fly* This curious property of producing a filk thread, which is common to fome Tea animals, fee Botanic Garden, Part I. Note XXVII and is de- figne-j for tne purpole of their transformation as in the filk- worm, is ufed for conveying themfelves from higher o^anches to lower ones of trees by fome caterpillars, and to make themfelves temporary nelts or tents, and by the fpider for entangling his prey Nor is it flrange that fo much knowledge Ihould !>e acquired by iuch fmall animals ; fmce there is rei-ion to imagine, that thefe infecls have the fenfe of touch, either in their probofcis, or their antennae, to a great degree of perfection ; and thence may poflefs, as far as their fphere extends, as accurate knowledge, and fubtile invention, as the difcoverers of human arts XVI. i. If we were better acquainted with the hiftories of thofe infecls that are iurmcd into foci- eties, as the bees, wafps, and ants, I make no doubt but we mould find, that their arts and im- provements arc not fo fimilar and uniform as they now O F I N S T I N C T. S«CT. XVI. 16. now appear to us, but that they arofe in the fame manner from experience and tradition, as the arts of our own fpecies ; though their reafoning is from fewer ideas, is bufied about fewer objects, and is exerted with lefs energy. There are fome kinds of infects that migrate like the birds "before mentioned. The locuft of warmer climates has. fometimes come over to England ; it is fliaped like a grafshopper, with very large wings, and a body above an inch in length. It is menti- oned as coming into Egypt with an eaft wind, " The Lord brought an eaft wind upon the land all that day and night, and in the morning the eaft wind brought the locuils, and covered the face of the earth, fo that the land was dark/' Exod. x. 13. The emigrations of thefe infects are mentioned in another part of the fcripture, <4 The locufts have no kipgj yet go they forth all them in bands." Prov xxx. 27. The accurate Mr. Adanfon, near the river Gam- bia in Africa, was witnefs to the migration of thefe infects. " About eight in the morning, in the jnonth of February, there iuddenly aroie over our heads a thick cloud., which darkened the air, and deprived us of the rays of the fun. We found it vras a cloud of locufts raifed about twenty or thirty fathoms from the ground, and covering an extent of feveral leagues ; at length a ihower of thefe in- fects defcended, and after devouring every green herb, while they refted, again refumed their flight. This cloud was brought by a ftrong eail-wind, and was all the morning in palling over the adjacent country/' (Voyage to Senegal, 158)^ In this country the gnats are fometimes feen to migrate in clouds, like the mufketoes of warmer climates, and our fwarrns of bees frequently travel many miles, and are faid in North America always to fly towards .the fouth. The prophet Ifaiah has a beautifu} SECT. XVI. 1 6. OFINSTINCf. *.\$ beautiful allufion to thefe migrations, cc The Lord fhall call the fly from the rivers of Egypt, and (hall hifs for the bee that is in the land of Affyria," lla. vii. 1 5. which has been lately explained by Mr. Bruce, in his travels to difcover the fource of the Nile. 2. I am well informed that the bees that were carried into Barbadoes, and other weftern iflands, ceafed to lay up any honey after the firft year, a* they found it not ufeful to them : and are now be- come very troublefome to the inhabitants of thofc iflands by infefting their fugar-houfes ; but thofe in Jamaica continue to make honey, as the cold north winds, or rainy feafons of that ifland, confine them at home for feveral weeks together. And the bees of Senegal, which differ from thofe of Europe only in fize, make their honey not only fuperior to ours in delicacy of flavour, but it has this fmgularity, that it never concretes, but remains liquid as fyrup, (Adanfon). From fome obfcrvations of Mr. Wild- man and of other people of veracity, it appears, that during the fevere part of the winter feafon for weeks together the bees are quite benumbed and torpid from the cold, -and do not confume any of their provifion. This itate of fleep, like that of fwallows and bats, feems to be the natural refourcer of thole creatures in cold climates, and the making of honey to be an artificial improvement. As the death of our hives of bees appears to be owing to their being kept fo warm, as to require food when thdr flock is exhaufted ; a very obferv- ing gentleman at my requeft put two hives for many weeks into a dry cellar, and obferved, during alt that time,, they did not confume any of their pro- vifion, for their weight did not decreafe, as it had done when they were kept in the open air. The lame obfervation is made in the Annual Regifter for A/68. p. 113. And the Rev. Mr. "White, in his- Method *'6 OF INSf iMCT. SEcf.XVI.,5. Method of preferring Bees, adds, that thofe on the north fide of his houfe confumed lefs honey in the winter than thofe on the fouth fide. There is another obfervatiori on bees well afcer- tained, that they at various times, when the feafon begins to be cold, by a general motion of their legs as they hang in clufters produce a degree of wSrmth^ which is eafily perceptible by the hand. Hence by this ingenious exertion, they for a long time pre- vent the torpid (late they would naturally fall into. According to the late obfefvations of Mr. Hun- ter, it appears that the bees-wax is not made front the duft of the anthers of flowers, which they bring home on their thighs, but that this makes what is termed bed-bread, and is ufed for the purpofe of feeding the bee-maggots ; in the fame manner but- terflies live on honey, but the previous caterpillar lives on ^vegetable leaves, while the maggots of large flies require flefh for their food$ and thofe of the ichneumon fly require infects for their food* What induces the bee who lives on honey to lay up vegetable pbwder for its young ? What induced trie butterfly to lay its eggs on leaves, when itfelf feeds on honey? What induces the other flies tb feek a food for their progeny different from what they confume themfelves ? If thefe are not deduc- tions from their own previous experience or obfer- vation, all the aftions of mankind mufl be refolved into inftinct. 3* The dormoufe con fumes but little of its food during the rigour of the feafon, for they roll them- felves up, or fleep, or lie torpid the greater}, part of the time ; but on warm funny days experience a ihort revival, and take a little food, and then relapfe into their former ftate." (Pennant Zbblog. p» 67*) Other animals^ that fleep in winter with- out laying up any provender, are obferved to go into . 1 6. OF INSTINCT. 217 into their winter beds fat and flrong, but return to day-light in the fpring feafon very lean and fee- ble. The common flies ileep during the winter without any provifion for their nourifhment, and are daily revived by the warmth of the fun, or of our fires. Thefe whenever they fee light endea- vour to approach it, .having obferved, that by its greater vicinity they get free from the degree of torpor that the cold produces ; and are hence in- duced perpetually to burn themfelves in our can- dles : deceived, like mankind, by the mifapplica- tionof their knowledge, Whiift many of the fub- terraneous infects, as the common worms, feem to retreat fo deep into the earth as not to be enlivened or awakened by the difference of our winter days ; and (top up their holes with leaves or draws, to prevent the frofts from injuring them, or the cen- tipes from devouring them. The habits of peace, or the ftratagems of war, of thefe fubterranean na- tions are covered from our view; but a friend of mine prevailed on a diftreiled worm to enter the hole of another worm on a bowling-green, and he prefently returned much wounded about his head. And I once faw a worm rife haftily out of the earth into the funfhine, and obferved a centipes hanging at its tail ; the centipes nimbly quitted the tail,, and feizing the worm about its middle, cut it in half with its forceps, and preyed upon one party while the other efcaped. Which evinces they have defign in (lopping the mouths of their habitations. 4. The wafp of this country fixes his habitation under ground, that he may not be affected with the various changes of our climate ; but in Jamaica he hangs it on the bough of a tree, where the feafons are lefs fevere. He weaves a very curious paper of vegetable fibres to cover his neft, which is con- ftructed on the fame principle with that of the bee, but with a different material \ but as his prey con- fiffe M OF INSTINCT. SECT. XVf. i& fifts of flefh, fruits, and infers, which are perifha- b!e commodities, he can lay up no provender for the winter. M. de Loubiefe, in his relation of Siam, fays, *c That in a part of that kingdom, which lies open to great inundations, all the ants make their fcttle- ments upon trees ; no ants' neiis are to be feen any where elfe." Whereas in our country the ground is their only fituation. From the fcriptural account of thefe infects, one might be led to fufpect, that in fome climates they lay up a provifion for the win- ter. Origen affirms the fame, v(Cont. Celf. L. 4.^ But it is generally believed that in this country they do not, (Prov. vi. 6. xxx. 25.) The white ants of the coaft of Africa make themfelves pyramids eight or ten feet high, on a bafe of about the fame width, with a fmooth furface of rich clay, exceflively hard and well t^uilt, which appear at at a diftance like an aifemblage of the huts of the negroes, (Adanfon.) The hiftory of thefe has been lately well defcribed in the Philofoph. Tranfaccions, under the name of termes, or termites. Thefe differ very much from the neft of our large ant ; but the real hiftory of this creature, as well as of the wafp, is yet very imperfectly known. Wafps are faid to catch large fpiders, and to cut off their legs, and carry their mutilated bodies to their young, Dicl. Raifon. Tom. I. p. 152. One circumllance I fhall relate which fell under my own eye, and (hewed the power of reafon in a wafp, as is it exercifed among men. A wafp, on a gravel walk, had caught a fly nearly as large as himfelf ; kneeling on the ground I obferved him feparate the tail and the head from the body parr, to which the wings were attached. He then took the body part in his paws, and rofe about two feet from the ground with it ; but a gentle breeze waft- ing the wings of the fly turned him round in the ;- OF INSTINCT. 219 air, and he fettled again with his prey upon the gravel. I then diftinctly obferved him cut off with his mouth, firft one of the wings, and then the other, after which he flew away with it unmolefted by the wind. Go, thou fluggard, learn arts and induftry from the bee, and from the ant ! Go proud reafoner, and call the worm thy fifter! XVII Conclufton. It was before obferved how much the fuperior accuracy of our fenfe of touch contributes to increafe our knowledge; but it is the greater energy and activity of the power of volition fas explained in the former Sections of this workj that marks man- kind, and has given him the empire of the world. There is a criterion by which we may diftinguifh our voluntary acts or thoughts from thofe that are excited by our fenfations : " The former are al- ways employed about the means to acquire plea- furable objects, or to avoid painful ones : while the latter are employed about the poffeffion of thofe that are already in our power." If we turn our eyes upon the fabric of our fel- low animals, we find they are fupported with bones, covered with {kins, moved by mufcles ; that they poffefs the fame fenfes, acknowledge the fame ap- petites, and are nourifhed by the fame aliment with ourfelves ; and we mould hence conclude from the ftrongeft analogy, that their internal faculties were alfo in fome meafure fimilar to our own, Mr. Locke indeed publifhed an opinion, that other animals pofiefled no abftract or general ideas, and thought this circumflance was the barrier be- tween the brute and the human world. But thefe abftra&ed ideas have been fince demonftrated by . I, ( Biihpp OF INSTINCT. Bifliop Berkley, and allowed by Mr. Hume, to have no exigence in nature, not even in the mind «f their inventor, and we are hence neceffitated to look for fome other mark of diftin&ion. The ideas and actions of brutes, like thofe of children, are almoft perpetually produced by their prefent plcafures, or their prefent pains ; and, ex- cept in the few inftances that have been mentioned in this Section, they feldom bufy themfelves about the means of procuring future blifs, or of avoiding future mifery. Whilft the acquiring of languages, the making of tools, and the labouring for money ; which are all only the means of procuring pleafure : and the praying to the Deity, as another means to procure happinefs, are chara&eriftic of human nature. . SECT, SecT.XVH. i. CATENATION OF MOTIONS, 221 SECT. XVII. THE CATENATION OF MOTIONS, I. i. Catenations of animal motion. 2. Are pw- duced by irritations^ by fenfations, by volitions* 3. They continue fome time after they bait been ex- cited. Caufe of catenation. 4. We can then exert eur att-ention on other objects. 5. Many catenations of motions go on together. 6. Some links of the catenations of motions may be left out without dif- uniting the chain. 7. Interrupted circles of motion continue confufedly till they come to the part of the Circle ', where they were dijlurbed. 8. Weaker ca- tenations are diJJ.evered by flronger. 9. Then new catenations take place. 10. Mitch effort prevents their reuniting. Impediment of fpeech. 1 1. Trains more eafily diffevered than circles. 12. Sleep deftroys volition and external ftimulus. II. 7«- flanccs of various catenations in a "sung lady play- ing on the harpjichord, HL \.V\} hat catenations are the Jlrongeft. %. Irritations joined with affociations from Jlronge ft connexions, Vital motions. 3. New links with increafed force ', cold fits of fever produced. 4. New links with decreafed force. Cold bath, 5. Irritation joined with fenfation. Inflammatory fever. Why children cannot tickle themfefaes* 6. Volition joined with fenfation. Irritative ideas of found become fenfible. 7. Ideas of imagination ^dijevered by irritation, by volition, production of furprife. I. i. To inveftigate with precifion the catena* tions of animal motions, it would be well to attend £9 the manner pf their production : but we cannot begin 222 CATENATION OF MOTIONS SECT. XVII' i; begin this difquifition early enough for this purpofe, as the catenations of motion feem to begin with life, and are only extinguifhable with it. We have fpoken of the power of irritation, of fenfation, of volition, and of aflbciation, as preceding the fibrous motions ; we now ftep forwards, and confider, that converfely they are in their turn preceded by thofe motions ; and that all the fucceffive trains or cir- cles of our actions are compofed of this twofold concatenation. Thofe we fhall call trains of ac- tion which continue to proceed without any flared repetitions ; and thofe circles of a&ion, when the parts of them return at certain periods, though the trains of which they confift, are not exaclly fimi- Jar. 'The reading an epic poem is a train of ac- tions ; the reading a fong with a chorus at equal diftances in the meafure conflitutes fo many circles of action. 2. Some catenations of animal motion are pro- duced by reiterated fucceffive irritations, as when we learn to repeat the alphabet in its order by fre- quently reading the letters of it. Thus the vermi- cular motions of the bowels were originally pro- duced by the fucceffive irritations of the paffing aliment ; and the fucceflion of actions of the auri- cles and ventricles of the heart was originally form- ed by fucceffive flimulus of the blood, thefe after- wards become part of the diurnal circles of animal actions, as appears by the periodical returns of hunger, and the quickened pulfe of weak people in the evening. Other catenations of animal motion are gradually acquired by fucceffive agreeable fenfations, as in learning a favourite fong or dance ; others by dif- agreeable fenfations, as in coughing or ni&itation ; thefe become aflbciated by frequent repetition, and afterwards compofe parts of greater circles, of ac- tion like thofe above mentioned. Other ECT. XVIL i. CATENATION OF MOTIONS. 223 Other catenations of motions are gradually ac- quired by frequent voluntary repetitions ; as when \ve deliberately learn to march, read, fence, or any mechanic art, the motions of many of our mufcles become gradually linked together in trains, tribes, or circles of aclion. Thus when any one at firft begins to ufe the tools in turning wood or metals ia a lathe, he wills the motions of his hand or fin- gers, till at length thefe actions become fo connected with the effect, that he feems only to will the point of the chifiel. Thefe are caufed by volition, con- nected by aflbciation like thofe above defcribed, and afterwards become parts of our diurnal trains or circles of action. 3. All thefe catenations of animal motions are li- able to proceed fome time after they are excited, un- lefs they are diflurbed or impeded by other irrita- tions, fenfations, or volitions ; and in many in- flances in fpite of our endeavours to flop them ; and this property of animal motions is probably the caufe of their catenation. Thus when a child re- volves fome minutes on one foot, the fpeclra of the ambient objects appear to circulate round him fome time after he falls upon the ground. Thus rhe palpitation of the heart continues fome time after the object of fear, which occafioned it, is re- moved. The blufh of fhame, which is an excefs of fenfation, and the glow of anger, which is an excefs of volition, continue fome time, though the affected perfon finds, that thofe emotions were caufed by miftaken facts, and endeavours to ex- tinguifh their appearance. See Sect. XII. i. 5. 4. When a circle of motions becomes connected by frequent repetitions as above, we can exert our attention ftrongly on other objects, and the conca- tenated circle of motions will nevertheless 'proceed in due order ; as whilfl you are thinking on this fubjects, 2*4 CATENATION OF MOTIONS. SECT. XVIt r. fubjedt, you ufe variety of mufcles in walking about your parlour, or fitting at your writing table. 5. Innumerable catenations of motions may pro- ceed at the fame time, without incommoding each other. Of thefe are the motions of the heart and arteries ; thofe of digeftion and glandular fecre- vion j of the ideas, or fenfual motions ; thofe of progreffion, and of fpeaking ; the great annual cir- cle of actions fo apparent in birds in their times of breeding and moulting ; the monthly circles of many female animals ; and the diurnal circles of Seeping and waking, of fulnefs and inanition* 6. Some links of fucceffive trains or of fynchron- ©us tribes of action may be left out without disjoin- ing the whole. Such are our ufual trains of recol- lection ; after having travelled through an enter- taining country, and viewed many delightful lawnsr rolling rivers, and echoing rocks ; in the recollec- tion of our journey we leave out the many dittricts,. that we crofTed, which were marked with no pecu- liar pleafure. Such alfo are our complex ideas, they are catenated tribes of ideas, which do not perfectly refembie their correfpondent perceptions* becaufe fome of the parts are omitted. 7. If an interrupted circle of actions is not en- tirely diflevered, it will continue to proceed con- fufedly, till it comes to the part of the circle, where it was interrupted. The vital motions in a fever from drunkcnnefs,, and in other periodical difeafes, are inftances of this circumftance. The accidental inebriate does not recover himfelf perfectly till about the fame hour on the fucceeding day.. The accuftomed: drunkard is disordered, if he haa not his ufual potation of fermented liquor. So if a confiderable part of a connected tribe of action be difturbed, that whole tribe goes on with confufion, till the part of the tiibe affected regains its accuftomed ca- tenations.. Stcr. XVII. i. CATENATION OF MOTIONS. 225 tenations. So vertigo produces vomiting, and a great fecretion of bile, as in fea-ficknefs, all thefe being parts of the tribe of irritative catenations. 8. Weaker catenated trains may be diffevered by the fudden exertion of the (Ironger. When a child firft attempts to walk acrofs a room, call to him, and he inftantly falls upon the ground. So \vhile I am thinking over the virtues of my friends, if the tea-kettle fpurt out fome hot water on my flocking ; the fudden pain breaks the weaker chain of ideas,, and introduces a new group of figures of its own. This circumflance is extended to fome unnatural trains of action, which have not been confirmed by long habit ; as the hiccough, or an ague-fit, which are frequently curable by iurprife. A young lady about eleven years old had for five days had a contraction of one mufcie in her fore arm, and another in her arm, which occurred four or five times every minute ; the mufcies were feen to leap, but without bending the arm. To coun- teract this new morbid habit, an iflue was placed over the convulfed mufcie of her arm, and an adhefive plafter wrapped tight like a bandage over the whole fore arm, by which the new motion* were immediately deflroyed, but the means were continued fome weeks to prevent a return. 9. If any circle of actions is difTevered, either by omiflion of fome of the links, as in fleep, or by infertion of other links, as in furprife, new ca- tenations take place in a greater or lefs degree. The lad link of the broken chain of actions be- comes connected with the new motion which has broken it, or with that which was neareit the link omitted ; and thefe new catenations proceed inftead of the old ones. Hence the periodic returns of ague-fits, and the chimeras of our dreams. 10. If a train of actions is diflevered, much ef- fort of volition or fenfation will preveju its being reftored. 226 CATENATION OF MOT IONS. SECT, xvrl 2. reftored. Thus in the common impediment of fpeech, when the aflbciation of the motions of the mufcles of enunciation with the idea of the word to be fpoken is difordered, the great voluntary ef- forts, which diftort the countenance, prevent the rejoining of the broken aflbciations. See No. II. ip. of this Section. It is thus likewife obfervable in fome inflammations of the bowels, the too flrong efforts made by the mufcles to carry forward the offending material fixes it more firmly in its place, and prevents the cure. So in endeavouring to re- cal to our memory fome particular word of a fen- tence, if we exert ourfelves too ftrongly about it, we are lefs likely to regain it. 1 1 . Catenated trains or tribes of action are eafier diflevered than catenated circles of action. Hence in epileptic fits the fynchronous connected tribes of action, which keep the body erect, are diffevered, but the circle of vital motions continues undifturb- cd. 12. Sleep deitroys the power of volition, and precludes the flimuli of external objects, and thence difievers the trains, of which thefe are a part; which confirms the other catenations, as thofe of the vital motions, fecretions, and abforptions ; and produces the new trains of ideas, which constitute our dreams. II. i. All the preceding circumflances of the catenations of animal motions will be more clearly underftood by the following example of a perfon learning mufic ; and when we recollect the variety of mechanic arts, which are performed by aflbciated trains of mufcular actions catenated with the effects they produce, as in knitting, netting, weaving ; and the greater variety of affociated trains of ideas caufed or catenated by volitions or fenfations, as in our &CT. XVI. 2. CATENATION OF MOT IONS. our hourly modes of reafoning, or imagining, or recolle&ing, we (hall gain fome idea of the innu- merable catenated trains and circles of aclion, which form the tenor of our lives, and which began, and will only ceafe entirely with them. 2. When a young lady begins to learn mufic, flic voluntarily applies herfelf to the characters of her mufic-book, and by many repetitions endeavours to catenate them with the proportions of found, of which they are fymbols. The idea excited by the mufical characters are ilowly connected with the keys of the harpfichord, and much effort is necef- fary to produce every note with the proper finger, and in its due place and time ; till at length a traia of voluntary exertions becomes catenated with cer- tain irritations. As the various notes by frequent repetitions become connected in the order, in which they are produced, a new catenation of fenfitive exertions becomes mixed with the voluntary ones above defcribed ; and not only the mufical fymbols of crotchets and quavers, but the auditory notes and tones at the fame time, become fo many fuc- ceffive or fynchronous links in this circle of cate- nated actions. At length the motions of her fingers become ca- tenated with the mufical characters ; and thefe no fooner ftrike the eye, than the finger prefles down, the key without any voluntary attention between them : the activity of the hand being connected with the irritation of the figure or place of the mufical fymbol on the retina ; till at length by fre- quent repetitions of the fame tune the movements of her fingers in playing, and the mufcles of the larynx in finging, become aflbciated with each other, and form part of thofe intricate trains and circles of catenated motions, according with the fe- cond article of the preceding propofidons in No. i. of this Section. 3, Befides 22S CATENATION OF MOTIONS. SECT. XVII. i- 3. Befides the facility, which by habit attends the execution of this mufical performance, a curi- ous circumftance occurs, which is, that when our young mufician has begun a tune, me finds herfelf inclined to continue it 5 and that even when (he is carelefsly finging alone without attending to her own fong ; according with the third preceding article. 4. At the fame time that our young performer continues to play with great exaclnefs this accuf- tomed tune, me can bend her mind, and that in- tenfely, on forfte other object, according with the fourth article of the preceding propofitions. The manufcript copy of this work was lent to many of my friends at different times for the pur- pofc of gaining their opinions and criticifms on many parts of it, and I found the following anec- dote written with a pencil opofite to this page, but am not certain by whom. " I remember fee- ing the pretty young actrefs, w;ho fucceeded Mrs* Arne in the performance of the celebrated Pad- lock, rehearfe the mufical parts at her harpfichord under the eye of her matter with great tafte and accuracy ; though I obferved her countenance full of emotion, which I could not account for ; at laft flic fuddenly burft into tears ; for (he had all this time been eyeing a beloved canary bird, fuffering great agonies, which at that inftant fell dead from its perch." 5. At the fame time many other catenated circles of action are going on in the perfon of our fair mufician, as well as the motions of her fingers, fuch as the vital motions, refpiration, the movements of her eyes and eyelids, and of the intricate mufcles of vocality, according with the fifth preceding article. 6. If by any ftrong impreflion on the mind of our fair mufician fhe fhould be interrupted for a very SECT. XVII. 2. CATENATION OF MOTIONS. 229 very inconfiderable time, (he can dill continue her performance, according to the fixth article. 7. If however this interruption be greater, though the chain of actions be not diiTevered, it proceeds confufedly, and our young performer continues indeed to play, but in a hurry without accuracy and elegance, till fhe begins the tune a- gain, according to the feventh of the preceding ar- ticles, 8. But if this interruption be ftjll greater, the circle of actions becomes entirely diffevered, and fhe finds herfelf immediately under the neceility Co begin over again to recover the loft catenation, ac- cording to the eighth preceding article. 9. Or in trying to recover it fhe will fing fome diifonant notes, or ftrike fomc improper keys, ac- cording to the ninth preceding article. 10. A very remarkable thing attends this breacli of catenation, if the performer has forgotten fome word of her fong, the more energy of mind me ufes about it, the more diftant is fhe from regaining it ; and artfully employs her mind in part on fome other object, or endeavours to dull its perceptions, continuing to repeat, as h were inconfciouily, the former part of the fonga that me remembers, in hopes to regain the loft co»- aexion. For if the activity of the mind itfelf be more energetic, or takes its attention more, than the connecting word, which is wanted ; it will not per- ceive the flighter link of this loft word ; as who liftens to a feeble found, muft be very filent and motionlefs ; fo that in this cafe the very vigour of the mind itfelf feems to prevent it from regaining the loft catenation, as well as the too great exer- tion in endeavouring to regain it, according to the tenth preceding article* We *$v CATENATION OF MOTIONS. SECT. XVlf 5. We frequently experience, when we are doubt- ful about the fpelling of a word, that the greater voluntary exertion we ufe, that is the more intenfely xve think about it, the further are we from regain- ing the loft affociation between the letters of it, but which readily recurs when we have become careiefs about it. In the fame manner, after hav- ing for an hour laboured to recollect the- name of fome abfent perfon, it (hall feem, particularly after fleep, to come into the mind as it were fpon- taneoufly ; that is, the word we are in fearch of, was joined to the preceding one by affociation ; this affociation being diffevered, we endeavour to recover it by volition; this very action of the mind (trikes our attention more, than the faint link of adbciation, and we find it impoffible by this means to retrieve the loft word. After fleep, when volition is entirely fufpended, the mind becomes capable of perceiving the fainter link of affociation, and the word is regained. On this circumftance depends the impediment of fpeech before mentioned ; the firft fyllable of a word i& caufable by volition, but the remainder of it is in common converfation introduced by its affociations with this firft fyllable acquired by long habit. Hence when the .mind of the ftammerer is vehemently em- ployed en fome idea of ambition of fhining, or fear of not fucceeding,- the aflbciations of the motions of the muicies or articulation with each other be- come diflevered by this greater exertion, and he en- deavours in vain by voluntary efforts to rejoin the - broken afibciation. For this purpofe he continues to repeat the fiift fy liable, which is caufable by vo- lition, and drives in vain, by various diftortions of countenance, to produce the next links, which are fubjedt to affociation. See Clafs IV. 3, I. i. 1 1 . After our accomplilhed mufician has acquired great variety of tunes and fongs, fo that fome of them . 2. CATENATION OF MOTIONS. 23; them begin to ceafe to be eafily recollected, fhc finds progreffive trains of mufical notes more fre- quently forgotten, than thofe which are compofed of reiterated circles, according with the eleventh preceding article. 12. To finifh our example with the preceding ar- ticles we muft at length fuppofe, that our fair per- former falls afleep over her harpfichord ; and thus by the fufpenfion of volition, and the exclufion of external ftimuli, fhe diflevers the trains and circles of her muficai exertions. III. i. Many of thefe circumftances of catenati- ons of motions receive an eafy explanation from the four following confequences to the feventh law of animal caufation in Seel. IV. Thefe are, firft, that thofe fucceflions or combinations of animal motions, whether they were united by caufation, aflbciation, or catenation, which have been mod frequently re- peated, acquire the flrongeft connection. Secondly, that of thefe, thofe, which have been lefs frequently mixed with other trains or tribes of motion, have the ftrongeft connection. Thirdly, that of thefe, thofe, which were firit formed, have the ftrongeft connecti- on. Fourthly, that if an animal motion be excited by more than one caufation, aflbciation, or catena- tion, at the fame time, it will be performed with greater energy. 2. Hence alfo we under (land, why the catenati- ons of irritative motions are more ftrongly connect- ed than thofe of the other clafles, where the quan- tity of unmixed repetition has been equal ; becaufe they were firft formed. Such are thofe of the fe- cerning and abforbent fyftems of veflels, where the action of the gland produces a fluid, which ftimu- lates the mouths of its correfpondent abforbents. The aflbciated motions feem to be the next mod ilrongly united, from their frequent repetition , and where both thefe circumftances unite, as in the vital motions *J2 CATENATION OF MOTIONS. SECT. XVII. 3. motions, their catenations are indiflbluble but by the deftru&ion of the animal. 3. Where a new link has been introduced into a circle of a&ions by fome accidental defect of ftimu- lus ; if that, defect of flimulus be repeated at the fame part of the circle a fecond or a third time, the defec- tive motions thus produced, both by the repeated jdefecl: of flimulus and by their catenation with the parts of the circle of actions, will be performed with lefs and lefs energy. Thus if any perfon is expofed to cold at a certain hour to day, fo long as to render fome part of the fyftem for a time torpid ; and is again expofed to it at the fame hour to-morrow, and the next day ; he will be more and more affecled by it, till at length a cold fit of fever is completely form- ed, as happens at the beginning of many of thofe fevers, which are called nervous or low fevers. Where the patient has flight periodical (hiverings and palenefs for many days before the febrile pa- roxyfm is completely formed* 4. On the contrary, if the expofure to cold be for To fhort a time, as not to induce any confiderable cFegree of torpor or rjuiefcepce, and is repeated daily as above mentioned, it lofes its effect more and more at every repetition, till the conftitution can bear it without inconvenience, or indeed with- out being confcious of it. As in walking into the cold air in frofty weather. The fame rule is appli- cable to increafed ftimulus,'as of heat, or of vinous fpirit, within certain limits, as is applied in the two laft paragraphs to Deficient Stimulus, as is further explained in Sed. XXXVI. on the Periods of DifV cafes. 5. Where irritation coincides with fenfation to produce the fame catenations of motion, as in inflam- matory fevers, they are excited with (till greater energy than by the irritation alone. So When chiU dren expeft to be tickled in play, by a feather light- ly paffed over the lips, or by gently vellicating the foles SICT. XVII. 3. CATENATION OF MOTIONS. 233 foles of their feet, laughter is moft vehemently ex- cited ; though they can ftimulate thefe parts with their own fingers unmoved. Here the pleafurable idea of playfulnefs coincides with the vellication ; and there is no voluntary exertion ufed to diminifh the fenfation, as there would be, if s. child fhould endeavour to tickle himfelf. See Seel:. XXXIV* i. 4- 6. And lafHy, the motions excited by the junc- tion of voluntary exertion with irritation are per- formed with more energy, than thofe by irritation fingly ; as when we liften to fmall noifes, as to the ticking of a watch in the night, we perceive the moft weak founds, that are at other times unheeded. So when we attend to the irritative ideas of found in our ears, which are generally not attended to, we can hear them ; and can fee the fpeclra of objects, which remain in the eye, whenever we pleafe to ex- ert our voluntary power in aid of thofe weak actions pf the retina, or of the auditory nerve. 7. The temporary catenations of ideas, which are caufed by the fenfations of pleafnre or pain, are eafily diflevered either by irritations, as when a fud- den noife difturbs a day-dream ; or by the power of volition, as when we awaken from fleep. Hence in our waking hours, whenever an idea occurs, which is incongruous to our former experience, we in- ftantly diflever the train of imagination by the power of volition, and compare the incongruous idea with our previous knowledge of nature, and reject it. This operation of the mind has not yet acquired a fpecific name, though it is exerted every minute of our waking hours ; unlefs it may be termed INTUITIVE ANALOGY. It is an aft of reafoning of which we- are unconfcious except from its effects in preferving the congruity of our ideas, and bears the fame relation to the fenforial power of volition, that irritative ideas, of which we are unconfcious except by CATENATION OF MOTIONS. SECT. XVIII. 5 by their effe&s, do to the fenforial power of irritati- on ; as the former is produced by volition without our attention to it, and the latter by irritation with- out our attention to them. If on the other hand a train of imagination or of voluntary ideas are excited with great energy, and paffing on with great vivacity, and become difiever- ed by fome violent ftimulus,. as the difcharge of a piftol near one's ear* another circumftance takes place, which is termed SURPRISE; which by ex- citing violent irritation, and violent fenfation, em- ploys for a time the whole fenforial energy, and thus diflevers the pafling trains of ideas, before the pow- er of volition has time to compare them with the jifual phenomena of nature. In this cafe fear is generally the companion of furprife, and adds to our embarraflment, as every one experiences in fome degree when he hears a noife in the dark, which he cannot inftantly account for. This cate- nation of fear with furprife is owing to our perpetual experience of injuries from external bodies in moti- on, unlefs we are upon our guard againft them. See Sett. XVIII. 17. and XIX. %. Many other examples of the catenations of animal motions are explained in Se&. XXXVI. on the Peri- 04s of Difeafes. SECT. . XVIII. OF S L E E P. 235 SECT. XVIII. OF SLEEP. i; Volition is fufpended in ficcp. 2. Senfation conti- nues. Dreams prevent delirium and inflammation. 3- Nightmare. 4. Ceafe lefs flow of ideas in dreams. 5. We feem to receive them by the fenfes. Optic nerve perfectly fenfibk in Jleep. Eyes lefs dazzled after dreaming of vifible objecls. 6- Reverie, be- lief. 7. How we diflinguijh ideas from percepti- ons. 8. Variety of fcenery in dreams, excellence of the fenfe of vifton. 9. Novelty of combination in dreams. 10. Dijttriftnefs of imagery in dreams. n. Rapidity of traufaftion in dreams. 12. Of meafuring time. Of dramatic time and place. Why a dull play induces Jleep, and an interefting one reverie. 13. Confcioiifnefs of our exigence and identity in dreams. 14. How we awake fometinws fuddenly, fometimes frequently. 15. Irritative mo- tions continue in Jleep , internal irritations are fuc~ cceded by fenfation. Senfibility increases during fleep, and irritability. Morning dreams. Why cpilepfies occur in Jleep. Ecftacy of children. Cafe of convuJJions in Jleep. Cramp, why painful* Aflhma. Morning fw eats. Increafe of heat. In- creafe of urine in jleep. Why more liable to take cold in jleep. Catarrh from thin night -caps. Why we feel chilly at the approach of Jleep, and at wak~ ing in the open air. 16. Why the gout commences in Jleep. Secretions are more copious in Jleep , young animals and plants grow more in Jleep. \ 7. Incon- fiflency of dreams. Abfence of furprife in dreams. i 8. Why we forget fome dreams and not others. \ 9. Sleep-talkers . awake with furprife. 20. Remote VOL. I. R OF SLEEP. SECT. XVIII. i. caufes of Jleep. dtmofphere with lefs oxygene. Comprejfton of the brain in fpina bifida. By whir- ling on an horizontal wheel. By cold. 21. Defini- tion of jleep. I. THERE are four fituations of our fyftem, which in their moderate degrees are not ufually termed dif- eafes, and yet abound with many very curious and inftrudtive phenomena ; thefe are fleep, reverie, vertigo, drunkennefs. Thefe we fhall previoufly confider, before we ftep forwards to develop the caufes and cures of difeafes with the modes of the operation of medicines. As all thofe trains and tribes of animal motion, which are fubje&ed to volition, were the lafl that were caufed, their connection is weaker than that of the other claffes ; and there is a peculiar circum- ftance attending this caufation, which is^ that it is entirely fufpended during ileep ; whilft the other claffes of motion, which are more immediately ne- ceflary to life, as thofe caufed by internal fUmuli, for inftance the pulfations of the heart and arteries, or thofe catenated with pleafurable fenfation, as the powers of digeftion, continue to ftrengthen their habits without interruption. Thus though man in his fkeping (late is a much lefs perfeft animal than in his waking hours ; and though he confumes more than one third of his life in this his irrational fitua- tion ; yet is the wifdom of the Author of nature manifeit. even in this feemin-g imperfection of his work ! The truth of this affertion with refpecl; to the large mufcles of the body, which are concerned in loco- motion, is evident ; as no one in perfect fanity walks about in his fleep, or performs any domeftic offices ; and in refpeft to the mind, we n^ver ex- ercife our reafon or recollection in dreams \ we may fometimes feem diftrafted between contending paf* SECT. XVIII. 2. OF SLEEP. 2F7 fions, but we never compare their obje£h, or deli- berate about the acquifition of thofe objects, if our ileep is perfect. And though many fynchronous tribes or fucceflive trains of ideas may reprefent the houfes or walks, which have real exigence, yet are they here introduced by their connection with our fenfations, and are in truth ideas of imagination, not of recollection. 2. For our fenfations of pleafure and pain arc ex- perienced with great vivacity in our dreams ; and hence all that motley group of ideas, which are caufed by them, called the ideas of imagination, with their various alTociated trains, are in a very vi- vid manner acted over in the fenforium ; and thefe fometimes call into action the larger mufcles, which have been much alTociated with them ; as appears from the muttering featences, which fome people utter in their dreams, and from the obfcure bark- ing of fleeprng dogs, and the motions of their feet and noftrils. This perpetual flow of the trains of ideas, which conftitute our dreams, and which are caufed by .painful or pleafurable fenfation, might at firfl view be conceived to be an ufelefs expenditure of fen- forial power. But it has been mewn, that thofe motions, which are perpetually excited, as thofe of the arterial fyftem by the ftimulus of the blood, are attended by a great accumulation of fenforial power, after they have been for a time fufpended ; as the hot-fit of fever is the confequence of the cold one* Now as thefe trains of ideas caufed by fenfation are perpetually excited during our waking hours, if they were to be fufpended in ileep like the voluntary motions, (which are exerted only by intervals du- ring our waking hours,) an accumulation of fenfo- rial power would follow ; and on our awaking- a delirium would fupervene, fince thefe ideas caufed by fenfation would be produced with fuch energy, R 2 that OF SLEEP. SECT. XVIII. 3. that we fhould miftake the trains of imagination for ideas excited by irritation ; as perpetually happens to people debilitated by fevers on their firft awak- ing ; for in thefe fevers with debility the general quantity of irritation being diminiflied, that of fen- fation is increafed. In like manner if the actions of the (lomachj: inteftines, and various glands, which are perhaps in part at lead caufed by or cate- nated with agreeable fenfation, and which perpetu- ally exift during, our waking hours, were like the voluntary motions fufpended in our fleep ; the great accumulation of fenforial power, which would ne- ceflfarily follow^ would be liable to excite inflamma- tion in them.- 3. When by our continued pofture in fleep, Jo me urieafy fenfations are produced, we either gra- dually awake by the exertion of volition, or the xnufcles connected by habit with fuch fenfations alter the pofition of the body ; but where the fleep is uncommonly profound,- and thofe uneafy fenfa- tions great, the difeafe called the incubus, or night- mare, is produced. -Here the defire of moving the. body is painfully exerted, by the power of moving it, or volition, is incapable of action, till we awake. Many lefs difagreeable druggies in our dreams, as when we wifli in vain- to fly from terri- fying objeds, conftitute a (lighter degree of this dif- eafe. In av/akkig from the nightmare I have more than once obferved, that there was no diforder in Hiy pulfe ; nor do I believe the refpiration i* labo- rious, as forne have affirmed. It occurs to people \vhoie ileep: is too profound, and fome difagreeable fenfation exifts, which at other times would have awakened them, and have .thence prevented the difeafe of nightmare j as after great fatigue or hun- ger with too large a fupper and wine, which oeca- fion our fleep- to be uncommonly profound* See No. i4> of this Sedion* 4- &* SECT. XVIII. 4. $. OF SLEEP. 4. As the larger mufcles of the body are much more frequently excited by volition than by fenfa- tion, they are but feldom brought into action in our fleep : but the ideas of the mind are by habit much more frequently connected with fenfation than with volition ; and hence the ceafelefs flow of our ideas in dr-eams. Every one's experience will teach him this truth, for we all daily exert much voluntary muicular motion: but few of mankind can bear the fatigue of much voluntary thinking. as occurs in moft dying perfons. Another way of procuring fleep mechanically was related to me by Mr. Brindley, the famous canal en- gineer, who was brought up to the bufinefs of a mill- wright j he told me, that he had more than once feer* 2$S O F SLEEP, SECT. XVIII, 21, ieen the experiment of a rn'an extending himfelf acrofs the large (lone of a corn-mill, and that by gradually letting the (lone whirl, the man fell afleep before the (lone had gained its full velocity, and he fuppofed would have died without pain by the con- tinuance or increafe of the motion. In this cafe the centrifugal motion of the head and feet muft accu- mulate the blood in both thofe extremities of the body, and thus comprefs the brain. JLafHy, we (hould mention the application of cold ; •which, when in a lefs degree, produces watchfulnefs by the pain it occafious, and the tremulous convul- fions of the fubcutaneous rnufcles ; but when it is applied in great degree, is faid to produce fleep. To explain this effect it has been faid, that as the veffels of the ikin and extremities become firft torpid by the want of the flimulus of heat, and as thence lefs blood is circulated through them, as appears from their palenefs, a greater quantity of biood poured upon the brain produces fleep by its com-preilion of that organ. But I (houl J rather imagine, that the fenforial power becomes exhaufted by the convulfive actions in confequence of the pain of cold, and of the voluntary exercife previoufly ufed to prevent it, and that the fleep is only the beginning to die, as the fufpenfion of voluntary power in lingering deaths precedes for many hours the extinction of the irrita- tive motions. 21. The following are the characteristic circum- ilances attending perfect fleep. j. The power of volition is totally fufpended. 2. The trains of ideas caufed by fenfation proceed with greater facility and vivacity; but become in- confi (lent with the ufual order of nature. The muf- cular motions caufed by fenfation continue ; as thofe concerned in our evacuations during infancy, and afterwards in digeftion, and in priapifmus. 3. The SECT. XVIII. 2i. OF SLEEP. 259 3. The irritative mufcular motions continue, as thofe concerned in the circulation, in fecretion, in refpiration. But the irritative fenfual motions, or ideas, are not excited ; as the immediate organs of fenfe are not (limulated into aclion by external ob- jects, which are excluded by the external organs of fenfe ^ which are not in fleep adapted to their reception by the power of volition, as in our waking hours. 4. The aflbciate motions continue; but their firfl: link is not excited into aclion by volition, or by external ftimuli. In all refpecb, except thofe above mentioned, the three lad fenforial powers are fomewhat increafed in energy during the fufpenfion of volition, owing to the confequeiit accumulation of the fpirit of animation. SECT, *6o OP REVERIE. SECT. XiX. i. SECT. XIX. OF REVERIE. i. Various degrees of reverie. 2. Sleep-walkers. Cafe of a young lady. Great furprife at awaking. And total forgetfulnefs of what faffed in reverie. 3. No fufpenfion of 'volition in reverie. 4. Senji- live motions continue ', and are confident. 5. Irri- iative motions continue, but are not fucceeded by fenfation. 6« Volition mceffary for the perception of feeble impreffions. -7. AJfrciated motions continue. 8. Nerves offenfe are irritable in fleep> but not in reverie. 9. Somnambuli are not afleep. Contagion received but once. \ o. Definition of reverie. i, WHEN we are employed with great fenfation of pleafure, or with great efforts of volition, in the purfuit of fome interefting train of ideas, we ceafe to be confcious of our exiilence, are inattentive to time and place, and do not diftinguifh this train of fenfitive and voluntary ideas from the irritative ones excited by the prefence of external objecls, though our organs of ienfe are furrounded with their ac- cuilorned ftimuli, till at length this interefting train of ideas becomes exhaufted, or the appulfes of ex- ternal objects are applied with unufual violence, and we return with furprife, or with regret, into the common track of life. This is termed reverie or ftudium. In fome conftitutions thefe reveries continue a confiderable time, and are not to be removed without greater difficulty, but are experienced in a lefs degree by us all ; when we attend earneftly to the ideas excited by volition or fenfation, with their ailbciated connexions, but are at the fame time SECT. XIX. 2. O F R E V E R I E. *6f time confcious at intervals of the ftiinuli of fur- founding bodies. Thus in being prefent at a play, or in reading a romance, fome perfons are fo totally abforbed as to forget their ufual time of fleep, and to neglect their meals ; while others are (aid to have been fo involved in voluntary ftudy as not to have heard the discharge of artillery ; and there is a ftory of an Italian politician, who could think fo intenfely on other fubjecls, as 'to be infenfible to the torture of the rack. From hence it appears, that thefe catenations of ideas and mufcular motions, which form the trains of reverie, are compofed both of voluntary and fenfitive aflbciations of them ; and that thefe ideas differ from thofe of delirium or of fleep, as they are kept confident by the power of volition ; ancl they differ alfo from the trains of ideas belonging to infanity, as they are as frequently excited by fenfation as by volition. But laitly, that the whole fenforial power is fo employed on thefe trains of complete reverie, that like the violent efforts of volition, as in convulfions or infanity ; or like the great activity of the irritative motions in drunken- nefs ; or of the fenfitive motions in delirium ; they preclude all fenfation confequent to external ftimulus. 2. Thofe perfons, who are faid to walk in their fleep, are affected with reverie to fo great a degree, that it becomes a formidable difeafe ; the eflence of which confifts in the inaptitude of the mind to at* tend to external ftimuli. Many hiflories of this difeafe have been publifhed by medical writers $ of which there is a very curious one in the Laufanne Tranfaftions. I fhall here fubjoin an account of fuch a cafe, with its cure, for the better illuf- tration of this fubject. A. very ingenious and elegant young lady, with light eyes and hair, about the age of feventeen, in other *62 OF REVERIE. -SECT. XIX. 2. other refpech well, was fuddenly feized focn after her ufual menflruation, with this very wonderful rnalady7 The difeafe began with vehement convul- fions of ahnoft every mufcle of her body, with great but vain efforts to vomit, * and the mod vio- lent hiccoughs, that can be conceived : thefe were fucceeded in about an hour with a fixed fpafm ; in which one hand was applied to her head, and the other to fupport k : in about half an hour thefe eeafed, and the reverie began fuddenly, and was at firft manifeft by the look of her eyes and counte- nance, which feemed to exprefs attention. Then fhe converfed aloud with imaginary perfons with her eyes open, and could not for about an hour be brought to attend to the flimulus of external ob- jects by any kind of violence, which it was proper to ufe : thefe fymptoms returned in this order every day for five or fix weeks. Thefe converfations were quite confident, and we could underftand, what (he fuppofed her imagi- nary companions to anfwer, by the continuation of her part of the difcourfe. Sometimes (he was an- gry, at other times (hewed much wit and vivacity, but was mod frequently inclined to melancholy. In thefe reveries (he fometimes fung over fome mufic with accuracy, and repeated whole pages from the Englifh poets. In repeating fome lines from Mr. Pope's works me had forgot one word, and began again, endeavouring to recollect it; when fhe came to the forgotten word, it was fhouted aloud in her ear, and this repeatedly to no purpofe; but by many trials fhe at length regained it her? felf. Thefe paroxyfms were terminated with the appear- ance of inexpreffible furprife, and great fear, from which fhe was fome minutes in recovering herfelf, Calling on her fitter with great agitation, and very frequently underwent a repetition of convulfions, apprentljr SECT. XIX, 2. OF REVERIE. 263 apparently from the pain of fear. See Sect. XVII. • After having thus returned for about an hour every day for two or three weeks, the reveries feemed to become lefs complete, and fome of their circumflances varied ; fo that (he could walk about the room in them without running againft any of the furniture ; though thefe motions were at firft very unfteady and tottering. And afterwards me once drank a diih of tea, when the whole appara- tus of the tea-table was fet before her ; and expref- fed fomc fufpicion, that a medicine was put into it, and once feemed to fmell of a tuberofe, which was in flower in her chamber, and deliberated aloud about breaking it from the'ftem, faying, " it would make her filler fo charmingly angry." At another time in her melancholy moments (lie heard the found of a palling beil, '* I wifh I was dead," me cried, liftening to the bell, and then taking off" one of her fhoes, as (he fat upon the bed, " I love the colour black," fays me, " a little wider, and a little longer, even this might make me a coffin I" — Yet it is evident, me was not fenfible at this timey any more than formerly, of feeing or hearing any perfon about her ; indeed when great light was thrown upon her by opening the mutters of the window, her trains of ideas feemed lefs melancho- ly ; and when I have forcibly held her hands, or covered her eyes, (lie appeared to grow impatient, and would fay, (he could not tell what to do, for fhe could neither fee nor move. In all thefe cir- cumftances her pulfe continued unaffected as in health. And when the paroxyfm was over, (he could never recollect a (ingle idea of what had palled in it. This afloniming difeafe, after^the life of many other medicines and applications in vain, was cured by very large dofes of opium given about an hour before *&4 6 F R E V-.E R I E. SECT. XIX. 3. 4 $. & before the expe&ed returns of the paroxyfms ; and after a few relapfes, at the intervals of three ot four months, entirely difappearetl. But (he conti- liued at times to have other fymptoms of epilepfy. 3. We fhall only here coniider, what had hap- pened during the time of her reveries, as that is our prefent fubjecl ; the fits of convulfion belong to another part of this treatife. Sett. XXXIV. 44. There feems to have been no fufpenfion of voli* lion during the fits of reverie, becaufe me endea- voured to regain the loft idea in repeating the lines of poetry, and deliberated about breaking the tube- fofe and fufpe&ed the tea to have been medicated. 4. 1 he ideas and mufcular movements depend- ing ^on fenfation were exerted with their ufual viva- city, and were kept from being inconfiftent by the power of volition, as appeared from her whole con- verfation, and was explained in Sett. XVII. 3. 7. and XVIII. 1 6. 5. The ideas and motions dependant on irrita- tion during the firft weeks of her difeafe, whilft the reverie was complete, were never fucceeded by the fenfation of pleafure or pain; as (he neither faw, heard, nor felt any of the furrounding objects. Nor was it certain that any irritative motions fuc- ceeded the ftimulus of external objects, till the re- verie became lefs complete, and then (he could walk about the room without running againft the furni- ture of it. Afterwards, when the reverie became ftill lefs complete from the ufe of opium, fome few irritations were at times fucceeded by her attention to them. As when (he fmelt at a tuberofe, and drank a difh of tea, but this only when (he feemed voluntarily to attend to them* 6. In common^life when tve liften to diftant founds, or wifli to diflinguifh objecls in the night, we are obliged flrongly to exert our volition to difpofe the organs of fenfe to perceive them, and to SECT. XIX. 7. O F R E V E R I E. 26$ to fupprefs the other trains of ideas, which might interrupt thefe feeble fenfations. Hence in the pre- fent hiftory the ftrongeft ftimuli were not perceived, except when the faculty of volition was exerted on the organ of fenfe ; and then even common ftimuli were fometimes perceived ; for her mind was fo ftrenuoufly employed in purfuing its own trains of voluntary or fenfitive ideas, that no common ftimuli could fo far excite her attention as to difunite them; that is, the quantity of volition or of fenfation al- ready exifting was greater than any, which could be produced in confequence of common degrees of ftimutation. But the few ftimuli of the tuberofe, and of the tea, which fhe did perceive, were fuch, as accidentally comcided with the trains of thought, which were palling in her mind ; and hence did not difunite thofe trains, and create furprife. And their being perceived at all was owing to the power of volition preceding or coinciding with that of irri- tation. This explication is countenanced by a fact men- tioned concerning a fomnambulift in the Laufanne Tranfa&ions, who fcmetimes opened his eyes for a fhort time to examine, where he was, or where his ink-pot (food, and then fhut them again, dipping his pen into the pot every now and then, and wri- ting on, but never opening his eyes afterwards, al- though he wrote on from line to line regularly, and corrected fome errors of the pen, or in fpelling: fo much eafier was it to him to refer to his ideas of the pofitions of things, than to his perceptions of them. 7. The afibciated motions perfifted in their ufual channel, as appeared by the combinations of her ideas, and the ufe of her mufcles, and the equality of her pulfe ; for the natural motions of the arte- rial fyftem, though origina'ly excited like other motions by ftimulus, feem in part to continue by their *66 Of* REVERIE. Si-.cT.XlX 8. 9} their aflociatibn with each other. As the heart of a viper pulfates long after it is cut out of the body, and removed from the ftimulus of the blood. 8. In the fection on fleep, it was obferved that the nerves of fenfe are equally alive 'and fuf- ceptible to 'irritation in that ftate, as when we are awake ; but that they are fecluded from ftimulating objects, or rendered unfit to receive them : but in complete reverie the reverfe happens, the immedi- ate organs of fenfe are e*xpofed to their ufual (li- mn li ; but are either not excited into action at all, or not into fp great action, as to produce attention or fenfation. The total forgetfulnefs of what Cartes in reveries ; and the. furprife on recovering from them, are ex- plained in Se&ion XVIII, 19. and in Section XVIL 3- 7- 9. It appears from hence, that rever e is a dif- eafe of the epileptic or cataleptic kind, fmce the paroxyfms of this young lady always began and frequently terminated with convulfia^s ; and though in its greateft degree it has been called fomnambu- lation, or fleep-walking, it is totally different from fleep ; becaufe the eflential character of ileep con- lifts in the total fufpenfion of volition, which in re- verie is not affected ; and tl>e eflential character of reverie confifts not in the abfence of thofe irritative motions of our fenfes, which are occafioned by the ftimulus of external objects, but in their never being productive of fenfation. So that during a fit of reverie that if range event happens to the whole, fyftem of nerves, which .occurs only to fome parti- cular branches of them in thofe, who are a fecond time expofed to the action of contagious matter. If the matter of the fmall-pox be inferted into the arm of one, who has previoufly had that difeafe, it will (limulate the wound, but the general fenfation or inflammation of the fyftem dees not follow, which fetcf. XIX. io. OF REVERIE. 267 which conftitutes the difeafe. See Sect. XII. 7. 6. XXXIII. 2. 8. 10. The following is the definition or character of complete reverie, i. The irritative motions occafioned by internal ftimuli continue, thofe from the ftimuli of external objects are either not pro- duced at all, or are never fucceeded by fenfation or attention, unlefs they are at the fame time excited by volition. 2. The fenfltive motions continue, and are kept confident by the power of volition. 3. The voluntary motions continue undifturbed. 4. The afibciated motions continue undifturbed. Two other cafes of reverie are related in Section XXXIV. 3. which further evince, that reverie is an effort of the mind to relieve fome painful fenfa- tion, and is hence allied to convulfion, and to in- fanity. Another cafe is related in Clafs III. j, 2. 2. VOL.I. T SECT, OF VERTIGO. SECT, XX, ». SECT. XX. OF.VLRT1GO. r .iteirjj- £t« a^jds* Js i I. We determine our perpendicularity by the apparent motions of objects. A 'per > on hood-winked cannot walk in a flraight line. Dizzinefi on looking from a low er, in a room Jluined with uniform lozenge s^ on riding over fnow. 2. Di^zinefs from moving objefts. A whirling 'wheel. Fluff nations of a river. ' ^Experiment with a child. 3. Bizzincfs from our own . motions and thofe of other objects. Riding over a .broad ftr earn. Sea-Jicknefs* 5. Of turning round .on me foot. Dervifes- in Turkey. Attention of tie ,mind prevents flight fea~ftcknefs. After a voyage ideas of vibratory motions are ft ill perceived onjhore. 6. Ideas continue fome time after they are excited. Circumftances of turning on one foot, Jlanding on a tower i and walking in the dark, explained. 7. /r- ritative ideas of apparent motions. Irr it alive ideas of founds \ Battement of the found of bells and organ-pipes. Vertiginous noife in the head. Irri~ tative motions of the flomach, intejHnes, and glands. 8. Symptoms thai accompany vertigo. Why vomit- ing comes on in ftrokes of the palfy. By the motion ef a fbip. By injuries on the head. Why motion wakes fjck people vomit. 9.. Why drunken people are vertiginous. Why ajlone in the ureter, or bile- duff\ produces vomiting, i o. Why after a voyage ideas of vibratory motions are perceived on Jborc. 1 1 . Kinds of vertigo and their cure. 1 2. Definition of vertigo. •*f*'jii£. '''"**&.'''': T. IN learning to walk fre judge of the difta-mres of the objeds, which we approach^ by the eye;, and by obferving^their perpendicularity determine our SECT. XX. i. OF VERTIGO. 169 our own. This circumftance not having been at- tended to by the writers on vifion, the difeafe call- ed vertigo or dizzinefs has been little underftood. When any perfon lofes the power of mufcular a&ion, whether he is ereft or in a fitting pofture, he finks down upon the ground : as is feen in fainting fits, and other inftarices of great debility. Hence it follows, that fome exertion of mufcular power is neceffary to preferve our perpendicular attitude. This is performed by proportionally exerting the antagonist mufeles of the trunk, neck, and limbs ; and if at any time in our locomotions we find our- felves inclining to one fide, we either reflore our equilibrium by the efforts of the mufeles on the other fide, or by moving one of our feet extend the bafe, which we reft upon, to the new center of gravity. But the moft eafy and habitual manner of deter- mining our want of perpendicularity, is by attend- ing to the apparent motion of the objecls within the fphere of diftincl: vifion ; for this apparent mo- tion of objecls, when we incline from our perpen- dicularity, or begin to fall, is as much greater than the real motion of the eye, as the diameter of the fphere of diftinct vifion is to our perpendicular height. Hence no one, who is hood-winked, can walk in a (traight line for a hundred fleps together ; for he inclines fo greatly, before he is warned of his want of perpendicularity by the fenfe of touch, not having the apparent motions of ambient objects to meafure this inclination by, that he is necefiitated to move one of his feet outwards, to the right or to the left, to fupport the new centre of gravity, and thus errs from the line he endeavours to proceed in. For the fame reafon many people become dizzy, when they look from the fumrmt of a tower, which T 2, i* 27* Of VERTIGO. SECT. XX. *, is raifed much above all other objects, as thefe ob- jects are out of the fphere of diftinct vifion, and they are obliged to balance their bodies by the lefs accu- rate feelings of their mufcles. There is another curious phenomenon belonging to this place, if the circumjacent vifible objects are fo fmall, that we do not diftinguifh their minute parts ; or fo fimilar, that we do not know them from each other ; we cannot determine our perpen- dicularity by them. Thus in a room hung with a paper, which is coloured over with fimilar fmall txlack lozenges or rhomboids, many people become dizzy ; for when they begin to fall, the next and the next lozenge fucceeds upon the eye; which fhey miftake for the firft, and are not aware, that they have any apparent motion. But if you fix a fheet of paper, or draw any other figure, in the midft of thefe lozenges, the charm eeafes, and no dizzinefs is perceptible.—- The fame occurs, when we ride over a plain covered with (ROW without trees or other eminent objects . 2. But after having compared vifible obje£ts at reft with the fenfe of touch, and learnt to diftinguifh their fhapes and fhades, and to meafure our want of perpendicularity by their apparent motions, we come to confrder them in real motion. Here a new diffi- culty occurs, and we require fome experience to learn the peculiar mode of motion of any moving objects, before we can make ufe of them for the purpofes of determining our perpendicularity. Thus fome people become dizzy at the fight of a whirling wheel, or by gazing on the fluctuations of a river, if no fleady objects are at the fame time within the fphere of their diflin-Ct vifion ; and wh-en a child firft can (land erect upon his legs, if you gain his attention to a white handkerchief fteadily extended like a fail, and afterwards make it undulate, he inftantly lofes his- perpendicularity, and tumbles on the ground. 3- ^ . XX. 3. 4. OF VERTIGO. 27* 3. A fecond difficulty we have to encounter is to diftinguifh our own real movements from the appa- rent motions of objects. Our daily praclice of walk- ing and riding on horfeback foon inftructs us with accuracy to difcern thefe modes of motion, and to afcribe the apparent motions of the ambient objects to ourfelves ; but thofe which we have not acquired by repeated habit, continue to confound us. So as we ride on horfeback the trees and cottages, which oc- cur to us, appear at reft ; we can meafure their dif- tances with our eye, and regulate our attitude by them : yet if we carelefsly attend to diftant hills or woods through a thin hedge, which is near us, we obferve the jumping and progreffive motions of them ; as this is increafed by the parallax of thefe objects ; which we have not habituated ourfelves to attend to. When firft an European mounts an elephant fixteen feet high, and whole mode of motion he is not ac- cuftomed to, the objects feem to undulate, as he pafles, and he frequently becomes fiek and vertigN nous, as I am well informed. Any other unufuai movement of our bodies has the fame eftect5 as riding backwards in a coach, fwinging on a rope, turning round fwiftly on one leg, fcating on the ice, and a thoufand others. So after a patient has been lopg confined to his bed, when he firft attempts to walk, he finds himfelf vertiginous, and is obliged by prac- tice to learn again the particular modes of the appa- rent motions of objects, as he walks by them. 4. A third difficulty, which occurs to us in learn- ing to balance ourfelves by the eye, is, when both ourfelves and the circumjacent objects are in real motion. Here it is neceffary that we mould be ha- bituated to both thefe modes of motion in order to preferve our perpendicularity. Thus on horfeback we accurately obferve another perfon whom we meet, trotting towards, without confounding his jumping and progreflive motion with our own, be- caufe *9* O P V E R T I G O. SECT. XX. f, caufe we have been accuftomed to them both ; that is, to undergo the one, and to fee the other at the fame time. But in riding over a broad and fluc- tuating ftream, though we are well experienced in the motions of our horfe, we are liable to become dizzy from our inexperience in that of the water. And when firii: we go on (hip-board, where the move- ments of ourfelves, and the movements of the large waves are both new to us, the vertigo is almoft un- avoidable with the terrible ficknefs, which attends it. And this I have been affured has happened to ft- veral from being removed from a large fliip into q. fmall one ; and again from a fmall one into a man of war. 5. From the foregoing examples it is evident, that, when we are furrounded with unufual motions, we Jofe' our perpendicularity : but there are fome pecu- liar circumstances attending this effeft of moving qbje&s, which we come now to mention, and (hall hope from the recital of them to gain fome infight into the manner of their production. When a child moves round quick upon one foot, the circumjacent objects become quite indiftincl:, as their diftance increafes their apparent motions ; and this great velocity confounds both their forms, and their colours, as is feen in whirling round a many coloured wheel ; he then lofes his ufual method of balancing himfelf by vifion, and begins to ftagger, and attempts to recover himfelf by his mufcuhr feelings. This daggering adds to the inftability of the vifible obje&s by giving a vibratory motion befides their rotatory one. This child then drops upon the ground, and the neighbouring objects ieem to continue for fome feconds of time tq circu- late around him, and the earth under him appears to librate like a balance. In fome feconds of time thefe fenfations of a continuation of the motion of pbjefts yanifh 5 but if he continues turning round fome what SECT. XX. 5. OF VERTIGO. , 273 fomewhat longer, before he falls, ficknefs and vo- miting are very liable to fucceed. But none of thefe circumftances affect thofe who have habituated themfelves to this kind of motion, as the dervifes in Turkey, amongft whom thefe fwift gyrations are a ceremony of religion. In an open boat palling from Leith to Kinghorn in Scotland, a fudden change of the wind fhook the utidiftended fail, and flopt our boat ; from this unufual movement the paflengers all vomited ex- cept myfelf I obferved, that the undulation of the (hip, and the inftability of all vifible objects, inclined me llrongly to be fick ; and this continued or increafed, when I clofed my eyes, but as often as I bent my attention with energy on the manage- ment and mechanifm of the ropes and fails, the ficknefs ceafed ; and recurred again, as often as I relaxed this attention ; and I am aflured by a gen- tleman of obfervation and veracity, that he has more than once obferved, when the veflel has been in immediate danger, that the fea-ficknefs of the paflengers has inftantaneouily ceafed, and recurred again, when the danger was over. Thofe, who have been upon the water in a boat or (hip fo long, that they have acquired the necef- fary habits of motion upon that unflable element, at their return on land frequently think in their re- veries, or between ileeping and waking, that they obferve the room, they fit in, or fome of its furni- ture, to librate like the motion of the veflel. This I have experienced myfelf, and have been told, that after long voyages, it is fome time before thefe ideas entirely vanifh. The fame is obfervable in a lefs degree after having travelled fome days in a ftage coach, and particularly when we lie down in bed, and compofe ourfelves to fleep; in this cafe it is obfervable, that the rattling noife of the coach, as well as the undulatory motion, haunts us. 274 OF VERTIGO. SECT. XX. 6, us. The drunken vertigo, and the vulgar cuftom of rocking children, will be confidered in the next Section. 6. The motions, which are produced by the power of volition, may be immediately flopped by the exertion of the fame power on the antagonifl mufcles ; otherwife thefe with all the other clafles of motion continue to go on, fome time after they are excited, as the palpitation of the heart conti- nues after the objeft of fear, which occafioned it, is removed. But this circijmftance is in no clafs of motions more remarkable than in thofe depen- dent on irritation ; thus if any one looks at the fun, -and then covers his eyes witji his hand, he will for many feconds of time, perceive the image of the fun marked on his retina: a fimilar image of all other vifible objects would remain fome time form- ed on the retina, but is extinguifhed by the perpe^ tual change of the motions of this nerve in our attention to other objects. To this mult be added, that the longer time any movements have continu- ed to be excited without fatigue to the organ, the longer will they continue fpontaneoufly, after the excitement is withdrawn : as the tafte of tobacco in the mouth after a perfon has been fmpaking it. This tafte remains To ftrong, that if a perfon con- tinues to draw air through a tobacco pipe lr\ the dark, after having been fmoking fome time, he cannot diftinguifh whether his pipe be lighted op not. From thefe two confederations it appears, that the dizzinefs felt in the head, after feeing objects in unufuai motion, is no other than a continuation pf the motions of {he optic nerve excited by thofe objects, and which engage our attention. Thus on turning round on one foot, the vertigo continues for fome feconds of time after the perfon is faller} pn the ground ; and the longer he has continued to SECT. XX. 7. OF VERTIGO. 275 jo revolve, the longer will continue thefe fucceffive motions of the parts of the optic nerve. See an additional note at the end of this volume. Any one who (lands alone on the top of a high , tower, if he has not been accuftomed to balance himfelf by objects placed at fuch diftances and with fuch inclinations, begins to dagger, and endea- vours to recover himfelf by his mufcular feelings. During this time the apparent motion of objects at a diftance below him is very great, and the fpectra of thefe apparent motions continue a little time after he has experienced them ; and he is perfua- ded to incline the contrary way to counteract their effects ; and either immediately falls, or applying his hands to the building, ufes his mufcular feelings to preferve his perpendicular attitude, contrary to the erroneous perfuafions of his eyes. Whilft the perfpn, who walks in the dark, daggers, but with- out dizzinefs ; for he neither has the fenfation of moving objects to take off his attention from his mufcular feelings, nor has he the fpectra of thofe motions continued on his retina to add to his con- fufion. It happens indeed fometimes to one (land- ing on a tower, that the idea of his not having room to extend his bafe by moving one of his feet outwards when he begins to incline, fuperadds fears to his other inconveniences ; which like fur- prife, joy, or any great degree of fenfation, ener- vates him in a moment^ by employing the whole fenforial power, and by thus breaking all the affo- ciated trains and tribes of motion. j. The irritative ideas of objects, whilft we are awake, are perpetually prefent to our fenfe of fight ; as we view the furniture of our rooms, or the ground, we tread upon, throughout the whole day without attending to it. And as our bodies are never at perfect reft during our waking hours, phefe irritative ideas of objects are attended perpe- tually 276 OF VERTIGO. SECT. XX. 7. tually with irritative ideas of their apparent moti- ons. The ideas of apparent motions are always irritative ideas, becaufe we never attend to them, whether we attend to the objects themfelves, or to their real motions, or to neither. Hence the ideas of the apparent motions of objefts are a complete circle of irritative ideas, which continue throughout the day. Alfo during all our waking hours, there is a perpetual confufed found of various bodies, as of the wind in our rooms, the fire, diftant converfa- tions, mechanic bufmefs ; this continued buzz, as we are feldotn quite motionlels, changes its loud- nefs perpetually, like the found of a bell ; which rifes and falls as long as it continues, and feems to pulfate on the ear. Thus any one may experience by turning himfelf round near a waterfall ; or by finking a glafs bell, and then moving the direction of its mouth towards the ears, or from them, as long as its vibrations continue. Hence this undu- lation of indiftincl: found makes another concomi- tant circle of irritative ideas, which continues throughout the day. We hear this undulating found, when we are perfectly at reft ourfelves, from other fonorous bodies befides bells ; as from two organ-pipes, which are nearly but not quite in unifon, when they are founded together. When a bell is ftruck, the circular form is changed into an elliptic one ; the longed axis of which, as the vibrations conti- nue, moves round the periphery of the bell ; and \vheneither axis of this eliipfe is pointed towards our ears, the found is louder ; and lefs when the intermediate parts of the ellipfe are oppofite to us. The vibrations of the two organ -pipes may be compared to Nonius's rule ; the found is louder, when they coincide, and lefs at the intermediate times. But, as the found of bells is the mod familiar X. 8. OF VERTIGO. ±77 familiar of thofe founds, which have a confidera^ ble battement, the vertiginous patients, who at- tend to the irritative circles of founds above de- fcribed, generally compare it to the noife of bells. The periftaltic motions of our ftomach and in- teftines, and the fecretions of the various glands, are other circles of irritative morions, fome of them more or lefs complete, according to our abftinence or fatiery. So that the irritative ideas of the apparent motions of objects, the irritative battements of founds, and the movements of our bowels and glands compofe a great circle of irritative tribes of motion: and when one confiderable part of this circle of motions becomes interrupted, the whole proceeds inconfu- fion, as defcribed in Seftion XVII. i. 7. on Catena- tion of Motions, 8. Hence a violent vertigo, from whatever caufe it happens, is generally attended with undulating noife in the head, perverfions of the motions of the ftomach and duodenum, unufual excretion of bile and gaftric juice, with much pale urine, fometimes with yellownefs of the (kin, and a difordered fecre- tion of almoft every gland of the body, till at Jength the arterial fyftem is affected, and fever fuc- ceeds. Thus bilious vomitings accompany the vertigo occafioned by the motion of a (hip ; and when the brain is rendered vertiginous by a paralytic affection of any part of the body, a vomiting generally enfues, and a great difcharge of bile : and hence great injuries of the head from external violence are fucceeded with bilious vomitings, and fome- times with abfcefles of the liver. And hence, when a patient is inclined to vomit from other caufes, as in fome fevers, any motions of the at- tendants in his room, or of himfelf when he is raifed 2,c5 OF VERTIGO. SECT. XX. 9. 10. taifed or turned in his bed, prefently induce the vomiting by fuperadding a degree of vertigo. 9, And converfely it is very ufual with thofe, whofe ftomachs are affected from internal caufes, to be afflidted with vertigo, and noife in the head ; fuch is the vertigo of drunken people, which con- tinues, when their eyes are clofed, and themfelves in a recumbent pofture, as well as when they are in an .erect pofture, and have their eyes open. And thus the irritation of a (ione in the bile-duel, or in the ureter, or an inflammation of any of the inteftines, are accompanied with vomitings and vertigo. In thefe cafes the irritative motions of the fto- mach, which are in general not attended to, become fa changed by fome unnatural flimulus, as to be* come uneafy, and excite our ienfation or attention. And thus the other irritative trains of motions, which are aflbciated with it, become difordered by their fympathy. The fame happens, when a piece of gravel (licks in the ureter, or when fome part of the inteftinal canal becomes inflamed. In thefe cafes the irritative mufcular motions are firft dif- turbed by unufuai ftimulus, sad a difordered aclion of the fenfual motions, or dizzinefs enures. While in fea-ficknefs the irritative fepfual motions, as. vertigo, precedes ; and the difordered ? irritative mufcular motions, as thofe of the-iloia^ch in yp- mhing, follow. 10. When thefe irritative motions are difturbed? if the degree be not very great, the exertion of voluntary attention to any other object, or any fadden fenfation, will disjoin thefe new habits of motion. Thus fome drunken people have becpme fober immediately, when any accident has ftrongly excited their attention ; and fea iicknefs has vanifn- ed, when the fhip has been in danger. Hence wheu our attention to other objecls is moft relaxed, •b? as. 8p.cT.XX.il. OF VERTIGO. 279 as jufl before we fall aileep, or between our reve- ries when awake, thefe irritative ideas of motion and found are mod liable to be perceived ; as thofe who have been at fea, or have travelled long in a coach, feem to perceive the vibrations of the (hip, or the rattling of the wheels, at thefe intervals ; which ceafe again, as foon as they exert their atten- tion. That is, at thofe intervals they attend to the apparent motions, and to the battement of founds of the bodies around them, and for a moment miftake them for thofe real motions of the (hip, and noife of wheels, which they had lately been accuftomed to : or at thefe intervals of reverie, or on the approach of fleep, thefe fuppofed motions or founds may be produced entirely by imagina- tion. We may conclude from this account of vertigo, that fea-ficknefs is not an effort of nature to relieve herfelf,, but a neceffary confequence of the affocia- tions of catenations of animal motions. And may thence infer, that the vomiting, which attends the gravel in the ureter, inflammations of the bowels, and the commencement of fome fevers, has a fimi- lar origin, and is not always an effort of the vis medicatrix naturae. But where the adion of the organ is the immediate confequence of the (limu- lating caufe, it is frequently exerted to dillodge that iiimulus, as in vomiting up an emetic drug ; at other times, the aftion of an organ is a general effort to relieve pain, as in convulsions of the loco- motive mufeles ; other actions drink up and carry on the fluids, as in abforption and fecretion ; all which may be termed efforts of nature to relieve, or to preferve herfelf. u. The cure of vertigo will frequently depend on our previoufly inveftigating the caufe of it, which irom what has been delivered above may originate from the diforder of any part of the great trihes of irritative *So OF VERTIGO. SECT. XX. ft. irritative motions, and of 'the aflbciate motions catenated with them. Many people, when they arrive at fifty or fixty years of age, are affected with flight vertigo; which is generally but wrongly afcribed to indigef- tion, but in reality arifes from a beginning defect of their fight ; as about this time they alfo find it neceifary to begin to ufe fpectacles* when they read fmall prints, efpecially in winter^ or by candle light, but are yet able to read without them during the fummer days, when the light is ftronger. Ihefe people do not fee objects fo diftinctly as formerly j and by exerting their eyes more than ufual, they perceive the apparent motions of objects, and con* found them with the real motions of them $ and therefore cannot accurately balance themfelves fo as eafily to preferve their perpendicularity by them. That is, the apparent motions of objects, which are at reft, as we move by them, mould only excite irritative ideas : but as thefe are now become lefs diftirict, owing to the beginning imperfection of our fight, we are induced voluntarily to attend ta them ; and then thefe appaient motions become fucceeded by fenfation ; and thus the other parts of the trains of irritative ideas, or irritative mufcular motions, become difordered, as explained above. In thefe cafes of flight vertigo I have always pro- mifed my patients, that they would get free from it in two or three months, as they mould acquire the habit of balancing their bodies by lefs diftinct ob- jects, and have feldom been miftaken in my prog- noftic. There is an auditofy vertigo, which is called a noife in the head, explained in No. *;. of this fecti- on, which alfo is very liable to affect people in the advance of life, and is owing to their hearing lefs perfectly than before. This is fometimes called a * ringing SECT. XX. ii. OF VERTIGO. *St ringing, and fometimes a fmging, or buzzing, in the ears, and is occafioned by our firft experiencing a difagreeable fenfation from our not being able diftindly to hear the founds, we ufed formerly to hear diftindly. And this difagreeable fenfation ex- cites defire and confequent volition ; and when we voluntarily attend to fmali indiftinft founds, even the whifpering of the air in a room, and the pulfa- tions of the arteries of the ear are fucceeded by fenfation ; which minute founds ought only to have produced irritative feniuai motions, or unperceived ideas. See Section XVII. 3. 6. Thefe patients after a while lofe this auditory vertigo, by acqui- ring a new habit of not attending voluntarily to thefe indiftinct founds, but contenting themfelves with the lefs accuracy of their fenfe of hearing. Another kind of vertigo begins with the diforder- ed action of fome irritative mufcular motions, a» thofe of the flomach from intoxication, or from emetics ; or thofe of the ureter, from the ftimulus of a (lone lodged in it ; and it is probable, that the difordered motions of fome of the great con- geries of glands, as of thofe which form the liver, or of the inteftinal canal, may occafion vertigo in confequence of their motions being affociated or catenated with the great circles of irritative moti- ons ; and from hence it appears, that the means of cure mud be adapted to the caufe. To prevent fea-ficknefs it is probable, that the habit of fwinging for a week or two before going on (hipboard might be of iervice. For the vertigo from failure of light, fpeclacies may be ufed. For the auditory vertigo, aether may be dropt into the ear to ftimulate the part, or to diffolve ear-wax, if fuch be a part of the caufe. For the vertigo arifing from indigeftion, the peruvian bark and a blifter are recommended. And for that owing to a (tone in Qfr VE&TIGO. Sicr.XX. ii. in the ureter, venefe&ion, cathartics, opiates, fa! foda aerated. 12. Definition of vertigo, i. Some of the irri- tative fenfual, or mufcular motions, which were ufually not fucceeded by fenfation, are in this dif- eafe fucceeded by fenfation ; and the trains or circles of motions, which were ufually catenated with them, are interrupted, or inverced, or proceed in confufion. 2. The fenfitive and voluntary mo- tions continue undifturbed. 3. The afibciate trains or circles of motions continue ; but their catena- tions with fome of the irritative motions are dif- ordered, or inverted, or dhTevered. SECT. SECT. XXI. i. OF DRUNKENNESS. 28^ SECT. XXI. OF DRUNKENNESS. I. Sleep from fatiety of hunger. From rocking children. From ur if or?n founds. 2. Intoxication from comriion food after fat ^te and Inanition. 3. From wine or opium. Chllnefs after meals. Vert/go- Why plea- fur e is produced by intoxication, and by fwinging and rocking children. And why pain is relie-ved by it. 4. Why drunkards ftagger and fiammer, and are liable to weep. 5. And become ddirlous^ flecpy, and Jlupid. 6. Or make pale urine and vomit. 7. Ob- jehs are feen double. 8. Attention of the mind dl- minifhes drunkenncfs. 9. Difordered irritative mo- tions of all the fenfes. io. Difeafes from drunken- nefs. ii. Definition of drunkennefs. I. IN the (late of nature when the fenfe of hun- ger is appeafed by the (limulus of agreeable food, the bufmefs of the day is over, and the human favage is at peace with the world, he then exerts little at- tention to external objects, pleafmg reveries of ima- gination fucceed, and at length Deep is the refult : till the nourimment which he has procured, is car- ried over every part of the fyftem to repair the inju- ries of action, and he awakens with frefh vigour, and feels a renewal of his fenfe of hunger. The juices of fome bitter vegetables, as of the pop- py and thelauro-cerafus, and the ardent fpirit pro- duced in the fermentation of the fugar found in ve- getable juices, are fo agreeable to the nerves of the ftomach, that, taken in a fmall quantity, they in- ftantly pacify the leafe of hunger j and the iuatten- lion to external ftimuli with the reveries of imagi- VOL. I. U nation. 284 OF DRUNKENNESS.- SECT. XXI. 2. £ nation, and fleep, fucceeds, in the fame manner as when the ftomach is filled with other lefs intoxicat- ing food. This inattention to the irritative motions occafiori- ed by external ftimuli is a very important circum- ftancein the approach of fleep, and is produced in- young children by rocking their cradles : during which all vifible objects become indiftinct to them. An uniform foft repeated found, as the murmurs of a gentle current, or of bees, are faid to produce the fame effect, by prefenting indiitindt ideas of in* eonfequential founds, and by thus ftealing our at- tention from other objects, whiift by their conti- nued reiterations they become familiar themfelves, and we ceafe gradually to attend to any thing, and fleep enfues. 2. After great fatigue or inanition, when the ftomach is fuddenly filled with flefh and vegetable food, rhe inattention to external ftimuli, and the reveries of imagination, become fo confpicuotis as to amount to a degree of intoxication. The fame is at any time produced by fuperadding a little wine OP ©pium to our common meals ; or by taking thefe fe- parately in confiderable quantity , and this more efficacioufly after fatigue or inanition -y becaufe a lefs quantity of any ftimulating material will excite an organ into energetic a6tion, after i£ has lately been torpid from defe£tof (timulus; as objects ap- pear more luminous, after we have been in the dark; and becaufe the fufpenfion of volition,- which is the immediate caufeof fleep, is fooner induced, after a continued voluntary exertion has in part exhausted the fenforial power .of volition ; in the fame manner as we cannot contract a fmgle mufcle long together without intervals of inaction. 3. In the beginning of intoxication we are inclined to fleep, as mentioned above, but by the excite- ment of external circumftances, as of noife, light^ bufmefc, SECT. XXI 3. OF DRUNKENNESS. 285 bufinefs, or by the exertion of volition, we prevent the approaches of it, and continue to take into our flomach greater quantities of the inebriating mate- rials. By thefe means the irritative movements of the flomach are excited into greater action than is natu- ral : and in confequence all the irritative tribes and trains of motion, which are catenated with them, become fufceptible of flronger action from their ac- cuflomed ftimuli ; becaufe thefe morions are excited both by their ufual irritation, and by their aifocia- tion with the increafed actions of the ftomach and lacteals. Hence the (kin glows, and the heat of the body is increafed, by the more energetic action of the whole glandular fyftem ; and pleafure is intro- duced in confequence of thefe increafed motions from internal flimulus. According to Law 5. Sect. IV. on Animal Caufation. From this great increafe of irritative motions from, internal flimulus, and the increafed fenfation intro- duced into the fyftem in confequence ; and fecondly, from the increafed fenfitive motions in confequence of this additional quantity of fenfation, fo much fenforial power is expended, that the voluntary power becomes feebly exerted, and the irritation from the flimulus of external objects is lefs forcible ; the ex- ternal parts of the eye are not therefore voluntarily- adapted to the diftances of objects, whence the ap- parent motions of thole objects either are feen dou- ble, or become too indiftinct for the purpofe of ba- lancing the body, and vertigo is induced. Hence we become acquainted with that very cu- rious circumflance, why the drunken vertigo is at- tended with an increafe of pleafure -, for the irritative ideas and motions occaficned by internal ftimulus, that were not attended to in our fober hours, are now juft fo much increafed as to be fucceeded by pleafurable fenfation, in the fame manner as the more violent motions of our organs are fucceeded by U a painful 286 OF DRUNKENNESS.- SECT. XXI. j, painful fenfaticn. And hence a greater' quantity of pleafurable fenfation is introduced into the conftitu- tion ; which is attended in feme people with an in- creafe of benevolence and good hurnour. If the apparent motions of objects is much increa- fed, as when we revolve on one foot, or are fwung on a rope, the ideas of thefe apparent motions are alfo attended to, and are fucceeded with pleafurable' fenfation, till they become familiar to us by frequent life. Hence children areatfirft delighted with thefe kinds of exercife, and with riding, and failing, and hence rocking young children inclines them to fleep. For though in the vertigo from intoxication the irritative ideas of the apparent motions of objects are indtflinct from their decreafe of energy : yet in the vertig,o occafioned by rocking or fwinging the irritative ideas of the apparent motions of ob- jects are increafed in energy, and hence they induce pleafure into the fyftem, but are equally indiftinct,. and in confequence equally unfit to balance our- felves by.- This addition of pleafure precludes de- fire or averfion, and in confequence the voluntary- power is feebly exerted, and on this account rock- ing young children inclines them to ileep. In what manner opium and wine act in relieving pain is another article, that well deferves our atten- tion. There are many pains that originate from de- fect as well as from: excefs of ftimulus ; of thefe are thofe of the fix appetites of hunger, thiril, lull, the want of heat, of (Mention, and of frefh air. Thus- if our cutaneous- capillaries ceafe to act from the diminifned ftimulus of heat, when we are expofed to cold weather, or our ftomach is uneafy for want of food ; thefe are both pains from defect of ftimulus, and in confequence opium,, which, llimulates all the moving fyftem into increafed action, muft relieve, them. But this is not the cafe in thofe pains, which, arife from excefs of ftimulus, as in violent inflamma^ tions : SECT. XXI. 4. 5. OF DRUNKENNESS. 287 cions : in thafe the exhibition of opium is frequent- ly injurious by increafing the adion of the fyftem already too great, as in inflammation of the bowels mortification is often produced by the ftimulus of opium. Where, however, no fuch bad confequen- ces follow ; the ftimulus of opium, by incieafing all the motions of the fyftem, expends fo much of the fenforial power, that the actions of the whole fyftem foon become feebler, and in confequence thofe which produced the pain and inflammation. 4. When intoxication proceeds a little further, (he quantity of pleafurable fenfation is fo far in- creafed, that all defire ceafes, for there is no pain in the fyftem to excite it. Hence the voluntary exer- tions are diminifhed, ftaggering and ftammering fuc- ceed ; and the trains of ideas become more and more inconfiftent from this defect of voluntary ex* ertion, as explained in the lections on deep and re- verie, whilft thofe pafTions which are unmixed with volition are more vividly felt, and (hewn with lefs referve ; hence pining love, or fuperftitious fear, and the maudlirg tear dropped on the remembrance of the moft trifling diftrefs. 5. At length all thefe circumftances are increafed; the quantity of pleafure introduced into the fyftem by the increafed irritative mufcular motions of the whole fanguiferous, and glandular, and abforbent fyftems, becomes fo great, that the organs of fenfe are more forcibly excited into action by this internal pleafurable fenfation, than by the irritation from the flimulus of external objects. Hence the drunkard ceafes to attend to external ftimuli, and as volition js nowalfo fufpended, the trains of his ideas become totally inconfiftent as in dreams, or delirium : and at length a ftupor fucceeds from the great ex- hauftion of fenforial power, which probably does not even admit of dreams, and in which, as in apo- plexy, no motions continue but thofe from internal ia from fenfation, and from affociation. 6. In 288 OF DRUNKENNESS. SECT. XXI. 6. 71 6. In other people a paroxyfm of drunkennefs has another termination ; the inebriate, as foon as he begins to be vertiginous, makes pale urine in great quantities and very frequently, and at length be- comes fick, vomits repeatedly, or purges, or has profufe fweats, and a temporary fever enfues with a quick (Irong pulfe. This in fome hours is fucceeded by flecp ; but the unfortunate bacchanalian does not perfectly recover himlelf till about the fame time of the fucceeding day, when his courfe of inebriation began. As fhewn in ^^ect XVII. r. 7. on Catena- tion. Th£ tempoiarv fever \vith (Irong pulfe is ow- ing to the fame cauitr as the glow on the fk»n men- tioned in the third paragraph of this Section : the flow of urine an<4 fickneis arifes fiorri the whole fyi- tem of irritative motions being thrown into confu- fion by their allbciaticns with each other ; as in fea- ficknefs, mentioned in Seel. XX. 4 on Vertigo : ancj which is more fully explained in bsct. XXIX. on Diabetes. 7. In this vertigo from internal caufes we fee ob- jects double, as two candles inftead of one, which is thus explained. Two lines drawn through the axes of our two eyes meet at the object we attend to : this angle of the optic axes increafes or diminiflies with the lefs or greater diitances of objecls. All ob- jects before or behind the place where this angle is formed, appear double; as any one may obferve by holding up a ppn between his eyes and the candle ; when he looks attentively at a fpot on the pen, and careicfsly at the candle, it will appear double ; and the reverfe when he looks attentively at the can- dle and careleisly at the pen ; fo that in this cafe the mufcies of the eye, like thofe of the limbs, Dagger and are difobedicnr to the expiring efforts of voli- tion Numerous objects are indeed fometimes feen by the inebriate, occafioned by the refractions made by the tears, which it and upon his eye-lids. 8. This SECT. XXI. 8. 9. OF DRUNKENNESS, 2-89 8. This vertigo alfo continues, when the inebriate lies in his bed, in the dark, or with his eyes clofedj and this more powerfully than when he is erect, and in the light. For the irritative ideas of the apparent motions of objeds are now excited by irritation from internal ftimulus, or by afibciation with other irri- tative motions ; and the inebriate, like one in a dream, believes the objects of thefe irritative mo- tions to be prefent, and reels himfelf vertiginous. I have obferved in this fituation, fo long as my eyes and mind were intent upon a book, the ficknefs and vertigo ceafed, and were renewed again the moment I difcontinued this attention ; as was explained in the preceding account of fea-ficknefs. Some drunken people have been known to become fober inftantly from fome accident, that has ftrongly excited their attention, as the pain of a broken bone, or the news of their houfe being on fire. 9. Sometimes the vertigo from internal caufes, as from intoxication, or at the beginning of fome fevers, becomes fo univerfal, that the irritative motions which belong to other organs of fenfe are fucceeded by fenfation or attention, as well as thofe of the eye. The vertiginous noife in the ears has been explained in Se£t. XX. on Vertigo. The tafte of the faliva, which in general is not attended to, becomes perceptible, and jthe patients complain of a bad tafte in their mouth. The common fmellsof the furroundingairfometimes excite the attention of thefe patients, and bad fmell? are complainedof, which to otherpeople are impercep- tible. The irritative motions that belong to the fenfe of prefTure, or of touch, areattendedto, andthepatient .conceives the bed to librate, and is fearful of falling out of it. The irritative motions belonging tothefenfes of diftention, and of hear, like thofe above mentioned, become attended to at this time : hence we feel the pul- fationof our arteries all over us, and complain of heat, or of cold in parts of the body where there is no ac- cumulation or diminution of a&ual heat. AH which i$o OF DRUNKENNESS. SECT. XXI. 10. are to be explained, as in the laft paragraph, by the irritative ideas belonging to the various fenfes being now excited by internal flimuli, or by their adora- tions with other irritative motions. And that thp inebriate, like one in a dream, believes the external objects, which ufually caufed thefe irritative ideas, tq be now prefent. TO. The difeafes in confequence of frequent ine- briety, or of daily taking much vinous fpirit without inebriety, confiit in the paralyfis which is liable to fucceed violent (limulation. Organs, whofe actions are affociated with others, are frequently more af- fected than the organ, which is ftimulated into too violent action. See Sect. XXIV. 2, 8. Hence in, drunken people it generally happens, that the; fecre- tpry veflels of the liver become firft paralytic, and a, torpor with confequent gall-ftones or fchirrus of this •vifcus is induced with concomitant jaundice ; other- wife it becomes inflamed in confequence of previous, torpor, and this inflammation is frequently transfer- red to a more fenfible part, which is aflbciated with it, and produces the gout, or the rofy eruption of the face, orforne other leprous eruption on the head, or arms, or legs. Sometimes the ftomach is firft affected, and paralyfis of the lacteal fyitem is indu- ced : whence a total abhorrence from Hem-food, and general emaciation. In others the lymphatic fyftem is affected with paralyfis, and dropfy is the confe- quence. In Tome inebriates the torpor of the liver produces pain without apparent fchirrus, or gall- hones, or inflammation, or confequent gout, and in thefe epilepfy or irifanity are often the confequence. All which will be more fully treated of in the courfe of this work. I am well aware that it is a common opinion, that the gout is as frequently owing to gluttony in eating, as to intemperance in drinking fermented or fpiri- tuous liquors. To this I anfwer, that I have feen no " ' SECT. XXI. 10. OF DRUNKENNESS. 29* no perfon afflicted with the gout, who has not drank freely of fermented liquor, as wine and water, or [mall beer : though as the difpofition to all the dif- eafes, which have originated from intoxication, is in fome degree hereditary, a lefs quantity of fpirituous potation will induce the gout in thofe, who inherit the difpofition from their parents. To which I rnuft add, that in \oung people therheumatiimis frequent- ly miftaken for the gout. Spice is feldom taken in fuch quantity as to do any material injury to the fyftem, flefh meats as well as vegetables are the natural diet of mankind ; with thefe a glutton maybe crammed up to the throat, and fed like a flailed ox ; but he will not be difeafed, unlefs he adds fpirituous or fermented liquor to his fooJ. This is well known in the diftilleries, where the fwine, which are fattened by the fpirituous fedi- ments of barrels, acquire difeafed livers. But mark •what happens to a man, who drinks a quart of wine or of ale, if he has not been habituated to it. He loies the ufe both of his limbs and of his un<- derftanding ! He becomes a temporary idiot, and has a temporary ftroke of the palfy ! And though he {lowly recovers after fome hours, is it not reafonable to conclude, that a perpetual repetition of fo power- ful a poifon mud at length permanently affecl: him ? If a perfon accidentally becomes intoxicated by eat- ing a few muftirooms of a peculiar kind, a general alarm is excited, and he is faid to be poifoned, and emetics are exhibited ; but fo familiarifed are we to the intoxication from vinous fpirit, that it occafions laughter rather than alarm. There is however confiderable danger in too hafti- ly difcontinuing the ufe of fo ftrong a ftimulus, left the torpor of the fyftem, or paralyfis, mould fooner be induced by the omiflion than the continuance of this habit, when unfortunately acquired. A golden pie for determining the quantity, which may with fafety 292 OF DRUNKENNESS SECT. XXI. u. fafety be difcontinued, is delivered in Section XII. 7. 8. u. Definition of drunkennefs. Many of the ir- ritative motions are much increafed in energy by in- ternal ftimulation. 2. A great additional quantity of pleafurable fenfation is occafioned by this increafed exertion of the irritative motions. And many fenfitive mo- tions are produced in confequence of this increafed fenfation. 3. The afibciated trains and tribes of motions, ca- tenated with the increafed irritative and fenfitive mo- tions, aredifturbed, and proceed in confufion. 4. The faculty of volition is gradually impaired, •whence proceeds the inflability of locomotion, inac- curacy of perception, and inconfiftency of ideas ; and is at length totally fufpended, and a temporary apoplexy fucceeds. SECT. . XXII. i. REPETITION AN-D IMITATION. SECT. XXII. OF PROPENSITY TO MOTION, REPETITION AND IMITATION. I. Accumulation of fen formal power in hemiplagia, in JliCj.. i'i (old fi; cj fever, in the locomotive mufcles, in the organs oj Jenfe. Produces propenfity to action. II. Repetition by three fenforial powers. In rhimes and alliterations, in mufic, dancing, architecture, land f cape -paint ing ^ beauty. III. i. Perception con- fifts in imitation. Four kinds of imitation. 2. Vo- luntary. Dogs taught to dance. 3. Senfitivc. Hence fympathy and all our virtues* Contagious matter of •venereal ulcers, of hydr ophobia, of jail-fever , of fmall- pox, produced by imitation, and the fex of the em- bryon. 4. Irritative imitation. 5. Imitations re- folvable into ajfociations. I. i. IN the henipiagia, when the limbs on one fide have loft their power of voluntary motion, the parent is for many days perpetually employed in moving thole of the other. 2. When the volun- tary power is fufpended during fleep, there commen- ces a ^eafeleis flow of fenfitive motions, or ideas of imagination, which compofe our dreams, 3. When in the cold fit of an intermittent fever fome parts of the Jyflem have for a time continued torpid, and have thus expended lefs than their ufual expenditure of fenforial power ; a hot fit fucceeds, with violent adion of thofe vefiels, which had previoufly been quiefcent. All thefe are explained from an accumu- lation of fenforial power during the inactivity of fome part of the fyftem. Befides the very great quantity of fenforial power perpetually produced and expanded in moving the arterial, 294. REPETITION AND IMITATION. SECT. XXII. j, arterial, venous, and glandular fyftems, with the va* rious organs of digeftion, as defcribed in Section XXXII. 3. 2, there is alfo a conftant expenditure of it by the action of our locomotive mufcles and or- gans of fenfe. Thus the4 thickhefs of the optic nerves, where they enter the eye, and the great ex- panfion of the nerves of touch beneath the whole of the cuticle, evince the great confumption of fenfo- rial power by thefe fenfes. And our perpetual muf- cular actions in the common offices of life, and in conftantly preferving the perpendicularity of our bodies during the day, evince a confiderable expen- diture of the fpirit of animation by our locomotive mufcles. It follows, if the exertion of thefe or- gans of fenfe and mufcles be for a while intermit- ted, that fome portion of fenforial power mufl be accumulated, and a propenfity to activity of fome kind enfue from the increafed excitability of the fyftem. Whence proceeds the irkfomenefs of a continued attitude, and of an indolent life. However fmall this hourly accumulation of the fpirit of animation may be, it produces a propenfity to fome kind of action ; but it neverthelefs requires either defire or averfion, either pleafure or pain, or fome external ftimulus, or a previous link of aflb- ciation, to excite the fyftem into adivity ; thus it frequently happens, when the mind and body are fp unemployed as not tp poflefs any of the three firft kinds of ftimulj, that the laft takes place, and con- fumes the fmall but perpetual accumulatipn of fen- forial power. Whence fome indolent people repeat the fame verfe for hours together, or hum the iamq tune. Thus the poet: Onward he trudged, not knowing what he fought, And whittled as he went, for want of thought. II. The Sect. XXI. 2. REPETITION AND IMITATION. 29- II. The repetitions of motions may be at firft produced either by volition, or by fenfation, or by irritation, but they foon become eafier to perform than any other kinds of action, becaufe they foon become afibciated together, according to Law the feventh, Section IV. on Animal Caufation. And becaufe their frequency of repetition, if as much fenforial power be produced during every reitera- tion as is expended, adds to the facility of th^ir pro- duction. If a (Umulus be repeated at uniform intervals of time, as defcribed in Section XII. 3. 3. the action, whether of our mufcles or organs of fenfe, is pro- duced with ftill greater facility or energy ; becaufe the fenforial power of aflbciation mentioned above, is combined with the fenforial power of irritation ; that is, in common language, the acquired habit af~ fifts the power of the ftimulus. This not only obtains in the annual, lunar, and diurnal catenations of animal motions, as explained in Section XXXVI. which are thus performed with great facility and energy; but in every lefs circle of actions or ideas, as in the burthen of a fong, or the reiterations of a dance. To the facility and diftinct- nefs, with which we hear founds at repeated inter- vals, we owe the pleafure, which we receive from, mufical time, and from poetic time ; as defcribed in Botanic Garden, P. 2. Interlude 3. And to this the pleafure we receive from the rhimes and allite- rations of modern verification ; the fource of which without this key would be difficult to difcover. And to this likewife fliould be afcribed the beauty of the duplicature in the perfect tenfe of the Greek verbs, and of fame Latin ones, as tango tetigi, mor- deo momordi. There is no vaiiety of notes referable to the gamut in the beating of the drum, yet if it be per- formed in mufical time, it is agreeable to our ears ; and 296 REPETITION AND IMITATION! SECT. XXII. 2. and therefore this pleafurable fenfation mu'ft be ow- ing to the repetition of the divifioris of the founds at terrain intervals of time, or mufical bars. Whe- ther thefe times or bars are diftinguifhed by a paufe, or by an emphafis or accent, certain it is, that this diftindlion is perpetually repeated ; othervvife the ear could not determine inftantly, whether the fuccef- fions of found were in common or in triple time. In common time there is a divifion between every two crotchets, or other notes of equivalent time ; though the bar in written mufic is put after every fourth crotchet, or notes equivalent in time ; i'n triple time the divifion or bar is after every three crotchets, or notes equivalent ; fo that in common time the repe- tition recurs more frequently than in triple time., The grave or heroic verfes of the Greek «nd Latin 'poets are written in common time ; the French he- toic verfes, and Mr. Anftie's humorous verfes in his Bath Guide, are Written in the fame time as the Greek and Latin verfes, but are one bar fhortef. The Englifh grave or heroic verfes are meafured by triple time, as Mr. Pope's tranfiation of Homer. But befides thefe little circles of mufical lime, there are the greater returning periods, and the ftill more diftant chorufes, which like the rhimes at the ends of verfes, owe their beauty to repetition; that is, to the facility and diftin&nefs with which we per- ceive founds, which we expect to perceive, or have perceived before; or in the language of this work, to the greater eafe and energy with which our organ is excited by the combined fenforial powers of aflb- ciation and irritation, than by the latter fingly, A certain uniformity or repetition of parts enters the very compofition of harmony. Thus two o&aves neare'l to each other in the fcale commence their vibrations together after every fecond vibration of the higher one. And where the firft, third, and fifth compofe a chord, the vibrations concur or coin- cide $*cf. XXII 3. REPETITION AND IMITATION. 297 cide frequently, though lefs fo than in the two oc- taves. It is probable that thefe chords bear fome analogy to a mixture of three alternate colours in the fun's fpectrum feparated by a prifm. The pleafure we receive from a melodious fuccef- iion of notes referable to the gamut is derived from another fource, viz. to the pandiculation or counter- action of antagonifl fibres. See Botanic Garden, P. 2. Interlude 3, If to thefe be added our early aflbciations of agreeable ideas with certain propor- tions of found, I fuppofe, from thefe three fources fprings all the delight of mufic, fo celebrated by ancient authors, and fo cnthufiaftically cultivated at prefent. See Se&. XVI. No. 10. on Inftinct. This kind of pleafure arifing from repetition, that is from the facility and diftinctnefs, with which we perceive and underftand repeated fenfations, enters into all the agreeable arts ; and when it is carried to: excefs is termed formality. The art of dancing like that of mufic depends for a great part of the plea- fure, it affords, on repetition j architecture, efpe- cially the Grecian, confifts of one part being a re- petition of another ; and hence the beauty of the pyramidal outline in landfcape-painting ; where one fide of the picture may be faid in fome meafure to balance the other. So univerfally does repetition contribute to our pleafure in the fine arts, that beau- ty itfelf has been defined by fome writers to confift in a due combination of uniformity and variety. See Sea. XVI. 6. III. i. Man is termed by Ariilotle an imitative animal \ this propenfity to imitation not only appears in the actions of children, but in all the cuftoms and fafhions of the world : many thoufands tread in the beaten paths of others, for one who traverfes regions of his own difcovery. The origin of this propenfity of imitation has nor, that I recollect, been deduced from any known principle ; when any ac- tion 29S REPETITION AND IMITATION. SECT. XXfT. 3. tion prefents itfelf to the view of a child, as of whetting a knife, or threading a needle, the parts of this action in refpect of time, motion, figure, are imitated by a part of the retina of his eye ; to per- form this action therefore with his hands is eafier to him than to invent any new action, becaufe it confifts in repeating with another fet of fibres, viz. with the moving mufcles, what he had juft performed by fome part of the retina ; juft as in dancing we transfer the times of motion from the actions of the auditory nerves to the mufcles of the limbs. Imi- tation therefore confifts of repetition, which we have fhewn above to be the eafieft kind of animal action, and which we perpetually fall into, when we pofiefs an accumulation of fenforial power, which is not otherwife called into exertion. It has been fhewn, that our ideas are configura- tions of the organs of fenfe, produced originally in confequence of the ftimulus of external bodies. And that thefe ideas, or configurations of the organs of fenfe, refemble in fome property a correfpondent property of external matter; as the parts of the ienies of fighi and of touch, which are excited into ac- tion, refemble in figure the figure of the ftimulating body ; and probably alfo the colour, and the quan- tity of denfity, which they perceive. As explained in Seel. XIV. 2." 2. Hence it appears, that our per- ceptions themfelves are copies, that is, imitations of fome properties of external matter; and the pro- penfity to imitation is thus interwoven with our ex- iftence, as it is produced by the ftimuli of external bodies, and is afterwards repeated by our volitions and fenfations, and thus conftitutes all the opera- tions of our minds. 2. Imitations refolve themfelves into four kinds, voluntary, fenfitive, irritative, and aflbciate. The vo- luntary imitations are, when we imitate deliberately the actions of others, either by mimicry, as in acting a play, . 3. REPETITION AMD IMITATION. 299 play, or in delineating a flower; or in the common actions of our lives, as in our drefs, cookery, lan- guage, manners, and even in our habits of think- ing. Not only the greateft part of mankind learn all the common arts of life by imitating others, biit brute animals feem capable of acquiring knowledge with greater facility by imitating each other, than by any methods by which we can teach them ; as dogs and cats, when they are fick, learn of each other to eat grafs ; and I fuppofe, that by making an artificial dog perform certain tricks, as in dancing on his hinder legs, a Irving dog might be eafily induced to imitate them ; and that the readied way of inftruct- ing dumb animals is by practifing them with others of the fame fpecies, which have already learned the artswewifhto teach them. The important ufe of imitation in acquiring natural language is mentioned in Sed. XVI. 7. and 8. on Inftinct. 3. The fenfitive imitations are the immediate con- fequences of pleafure or pain, and thefe are often pro- duced even contrary to the efforts of the will. Thus many young men on feeing cruel furgical operations become fick, and fome even feel pain in the parts of their own bodies, which they fee tortured or wounded in others ; that is, they in fome meafure imitate by the exertions of their own fibres the violent actions, which they witnefTed in thofe of others. In this cafe a double imitation takes place, firft the obferver imi- tates with the extremities of the optic nerve the mangled limbs, which are prefent before his eyes ; then by a fecond imitation he excites fo violent action of the fibres of his own limbs as to produce pain in thofe parts of his own body, which he faw wounded in another. In thefe pains produced by imitation the effect has fome fimilarity to the caufe, which dif- tinguifhes them from thofe produced by allociation ; as the pains of the teeth, called tooth-edge, which VOL. I. X are REPETITION AND IMITATION. SECT. XXH. 5. are produced by afibciation with difagreeable founds, as explained in Sect. XVI. 10. The effect of this powerful agent, imitation, in the moral world, is mentioned in Sect. XVI. 7. as it is the foundation of all our intellectual fympathies with the pains and pleafures of others, and is in confequence the fotfrce of all our virtues. For in what confifts our fympathy with the miferies, or with the joys, of our fellow creatures, but in an in- voluntary excitation of ideas in fome meafure fimi- lar or imitative of thofe, which we believe to exift in the minds of the peifons, whom we commiferate or congratulate ? There are certain concurrent or fucceflive actions of fome of the glands, or other parts of the body, which are pofleffed of fenfation, which become in- telligible from this propenfity to imitation. Of thefe are the production of matter by the mem- branes of the fauces, or by the ikin, in confequence erf the venereal difeafe previoufly affecting the parts of generation. Since as no fever is excited, and as nei- ther the blood of fuch patients, nor even the matter from ulcers of the throat, or from cutaneous ulcers, will by inoculation produce the venereal difeafe in others, as obferved by Mr. Hunter, there is reafon to conclude, that no contagious matter is conveyed thither by the blood -veffels, but that a milder matter is formed by the actions of the fine veffels in thofe membranes imitating each other. See Sect. XXXIII. a. 9. In this difeafe the actions of thefe veflels pro- ducing ulcers on the throat and (kin are imperfect imitations of thofe producing chancre, orgonorrhoea j frnce the matter produced by them is not infectious, while the imitative actions in the hydrophobia ap- pear to be perfect refemblances, as they produce a material equally infectious with the original one, "which induced them, The 3. REPETITION AND IMITATION. 301 The contagion from the bite of a mad dog dif- fers from other contagious materials, from its being communicable from other animals to mankind, and from many animals to each other ; the phenomena attending the hydrophobia are in fame degree expli- cable on the foregoing theory. The infectious mat- ter does not appear to enter the circulation, as it can- not be traced along the courfe of the lymphatics from the wound, nor is there any fwelling of the lympha- tic glands, nor does any fever attend, as occurs in the fmall-pox, and in many other contagious difeafes ; yet by fome unknown procefs the difeafe is commu- nicated from the wound to the throat, and that many months after the injury, fo as to produce pain and hydrophobia, with a fecretion of infectious fali- va of the fame kind, as that of the mad dog, which inflicted the wound. This fubject is very intricate. — It would appear, that by certain morbid actions of the falivary glands of the mad dog, a peculiar kind of faliva is produced; which beirig inftilled into a wound of another ani- mal, ftimulates the cutaneous or mucous glands into morbid actions, but which are ineffectual in refpect to the production of a fimilar contagious material ; but the falivary glands by irritative fympathy are thrown into fimilar action, and produce an infectious faliva fimilar to that inftilled into the wound. Though in many contagious fevers a material fimilar to that which produced the difeafe, is thus generated by imitation ; yet there are other infectious materials, which do not thus propagate themfelves, but which feem to act like flow poiibns. Of this kind was the contagious matter, which produced the jail-fever at the afllzes at Oxford about a century ago. Which, though fatal to many, was not com- municated to their nurfes or attendants. In thefe cafes, the imitations of the fine veflels as above def- cribed, appear to be imperfect, and do not therefore X 2 produce 302 REPETITION AND IMITATION. SECT. XXfl. 4.$. produce a matter fimilar to that, which ftimulates them ; in this circumftance refembling the venereal matter in ulcers of the throat or fkin, according to the curious difcovery of Mr. Hunter above related, who found, by repeated inoculations, that it would not infect. Hunter on Venereal Difeaie, Part vi. eh. i. Another example of morbid imitation is in the prodtt&ion of a great quantity of contagious matter, as in the inoculated fmall-pox, from a fmall quan- tity of ft infer ted into the arm, and probably diffufed in the blood* Thefe particles of contagious matter flimulate the extremities of the fine arteries, of the fkin, and caufe them to imitate fome properties of thofe particles of contagious matter, fo as to produce a thousandfold of a fimilar material. See Section XXXIII. 2. 6. Other inftances are mentioned in the Section on Generationy which mew the probabi- lity that the extremities of the feminal glands may imitate certain ideas of the rnindy or actions of the organs of fenfe, and thus occafion the male or fe- male fex of the embryon. See Sect. XXXIX. 6. 4. We come now to thofe imitations, which are not attended with fenfation. Of thefe are all the ir- ritative ideas already explained, as wheff the retina of the eye imitates by its action or configuration the tree or -the bjench, which I fliun in walking, pad without attending to them. Other examples of thefe irritative imitations are daily obfervable in common life; thus one yawning perfon mall feta whole com- pany a yawning ; and fome have acquired winking of the eyes or impediments of fpeech by imitating their companions without being confcious of it. 5. Befides the three fpecies of imitations above defcribed there may be fome aflbciate motions, which may imitate each other in the kind as well as in the quantity of their action ; but it is difficult to diftin- them from the alfoclatipas of motions treated SECT. XXII. 5. REPETITION AND IMITATION. 303 of in Se&ion XXXV. Where the aftions of other perfons are imitated, there can be no doubt, or where \veimitateapreconceivedidea by exertion of our locomotive mufcles, as in painting a dragon ; all thefe imitations may aptly be referred to the fources above defcribed of the propenfity to activity, and the facility of repetition ; at the fame time I do not affirm, that all thofe other apparent fenfitive and ir- ritative imitations may not be refolvable into affo- ciations of a peculiar kind, in which certain diftant parts of fimilar irritability or fenfibility, and which have habitually acted together, may affect each other exactly with the fame kinds of motion ; as many parts are known to fympathife in the quantity of their motions. And that therefore they may be ultimately refolvable into alfociadons of aftion, as defcribed in. Sett, XXXV. SECT, '304 OF THE CIRCULATORY SYSTEM. SECT. XXIII. i. SECT. XXIII. OF THE CIRCULATORY SYSTEM. I. The heart and arteries have no antagonift mufcles. Veins abforbtbe blood, propel it forwards, and di/tcnd the heart ; contraction of the htart diftends the ar- teries. Vena port arum. II. Glands which take their fluids from the blood. With long necks, with fljort necks. II], Ahforbent fyjlem. IV. Heat given out from glandular fecretions. Blood changes colour in the lungs and in the glands and capillaries. V. Blood is abforbed by veins, as chyle by lafteal veffels, otber- ivife they could not join their ftreams. VI. Two kinds offtimulus, agreeable and difagreeable. Glandular appetency. Glands originally poffejjed fenfation. I. WE now ftep forwards to itluftrate fome of the phenomena of difeafes, and to trace out their mod efficacious methods of cure ; and (hall commence this fubjeft with a fhort defcription of the circulatory fyftem. As the nerves, whqfe extremities form our various organs of fenfe and mufcles, are all joined, or com- municate, by means of the brain, for the convenience perhaps of the diftribution of a fubtile etherial fluid for the purpofe of motion ; fo all thqfe veflels of the body, which carry the grofler fluids for the purpofes of nutrition, communicate with each other by the heart. The heart and arteries are hollow mufcles, and are therefore indued with power of contraction ir^ confecjuence of ftimulus, like all other mufcular fibres ; but, as they have no antagonift mufcles, thq cavities of the veifels, which they form, would re- main SECT. XXIII. i. OF THE CIRCULATORY SYSTEM. 305 main for ever clofed, after they have contra&ed themfelves, unlefs forne extraneous power be applied to a^ain diftend them. This extraneous power in refpect to the heart is the current of blood, which is perpetually abforbed by the veins from the various glands and capillaries, and pufhed into the heart by a power probably very fimiiar to that, which raifes the fap in vegetables in the fpring, which, accord- ing to Dr. Hale's experiment on the ftump of a vine, exerted a force equal to a column of water above twenty feet high. This force of the current of blood in the veins is partly produced by their abfor- bent power, exerted at the beginning of every fine ramification ; which may be conceived to be a mouth abforbing blood, as the mouths of the la&eals and lymphatics abforb chyle and lymph. And partly by their intermitted compreflion by the pulfations of their generally concomitant arteries ; by which the blood is perpetually propelled towards the heart, as the valves in many veins, and the abforbent mouths in them all, will not fuffer it to return. The blood, thus forcibly injected into the cham- bers of the heart, diftends this combination of hol- low mufcles ; till by the ftimulus of diflention they contract: themfelves ; and, pufhing forwards the blood into the arteries, exert fufficient force T.Q overcome in lefs than a fecond of time the vis iner- tise, and perhaps fome elafticity, of the very extenr five ramifications of the two great fyflems of the aortal and pulmonary arteries. The power neceflary to do this in fo fhort a time muft be confiderable, and has been varioufly eitimated by different phyfio- logifls. The mufcular coats of the arterial fyftem are then brought into aclion by the ftimulus of diflention, and propel the blood to the mouths, or through the Convolution^ 306 OF THE CIRCULATORY SYSTEM. SECT. XXIII. 2, convolutions, which precede the fecretory apertures of the various glands and capillaries. In the veflels of the liver there is no intervention of the heart; but the vena portarum, which does the office of an artery, is diftended by the blood poured into it from the mefenteric veins, and is by this diftention ftimulated to contract itfelf, and propel the blood to the mouths of the numerous glands, which compofe that vifcus. II. The glandular fyftem of veffels may be di- \ided into thofe, which take fome fluid from the circulation ; and thofe, which give fomething to it. Thofe, which take their fluid from the circulation are the various glands, by which the tears, bile, urine, perfpiration, and many other fecretions are produ- ced ; thefe glands probably confift of a mouth to fele£i, a belly to digeft, and an excretory aperture to emit their appropriated fluids \ the blood is con- veyed by the power of the heart and arteries to the irjouths of thefe. glands, it is there taken up by the living power of the gland, and carried forwards to it? belly, and excretory aperture, where a part is fe- parated, and the remainder abforbed by the veins for further purpofes. Some of thefe glands are fqrnimed with long con- voluted necks or tubes, as the feminal ones, which are curioufly feen when injected with quickfilver. Others feem to confift of fharter tubes, as that great congeries of glands which conftitute the liver, and thole of the kidneys Some have their excretory apartures opening into refervoirs, as the urinary and gall bladders. And others on the external body, as thofe which fecrete the tears, and perfpirable matter. Another great fyftem of glands, which have very fhor t necks, are the capillary veiTels ; by which the mienfibie perfpiration is fecreted on the fkin; and . . • . : * : 4 • , • ; ,• • , : ;,.*-• • »i i . .' the SECT. XXIII. 3- OF THE CIRCULATORY SYSTEM. 307 the mucus of various conf.ftencies, which lubricate;? the interfaces of the cellular membrane, of the muf- cular fibres, and of all the larger cavities of the body. From the want of a long convolution of vef- fels fome have doubted, whether thefe capillaries fhould be confidered as glands, and have been led to conclude, that the perfpirable matter rather exuded than was fecreted. But the fluid of perfpiration is not fimple water, though that part of it which ex- hales into the air may be iuch ; for there is a part of it, which in a (late of health is abforbed again ; but which, when the abfarbents are difeafed, remains on the furface of the ikin, in the form of fcurf, or in- durated mucus. Another thing, which (hews their fimilitude to other glands, is their fenfibility to cer- tain affections of the mind ; as is leen in the deeper colour of the fkin in the blufh of mame,,or the greater palenefs of it from fear. III. Another feries of glandular vefTels is called the abforbent fyftem ; thefe open their mouths into ^11 the cavities, and upon all thofe furfaces of the body, where the excretory apertures of the other glands pour out their fluids. The mouths of the abforbent fyftem drink up a part or the whole of thefe fluids, and carry them forwards by their living power to their refpe&ive glands, which are called conglobate glands. There thefe fluids undergo fome change, before they pafs on into the circula- tion ; but if they are very acrid, the conglobate gland fwells, and fometime fuppurates, as in inocu- lation of the fmall-pox, in the plague/ and in vene- real abforptions ; at other times the fluid may per- haps continue there, till it. undergoes fome chemical change, that renders it lefs noxious ; or, what is more likely, till it is regurgitated by the retrograde motion of the gland in fpontaneous fweats or diar- rhoeas 308 OF THE CIRCULATORY SYSTEM. SECT. XXIII. 4. rhceas, as difagreeing food is vomited from the do- mach. IV. As all the fluids, that pafs through thefe glands, and capillary veflels, undergo a chemical change, acquiring new combinations, the matter of heat is at the fame time given out ; this is apparent, fmce whatever increafes infenfible perfpiration, in- creafes the heat of the ikin ; and when the adion of thefe veflels is much increased but for a moment, as in blufhing, a vivid heat on the (kin is the immediate confequence. So when great bilious fecretions, or thofe of any other gland, are produced, heat is generated in the part in proportion to the quantity of the fecretion. The heat preduced on the fkin by blufhing may be thought by fome too fudden to be pronounced a chemical effect, as the fermentations or new com- binations taking place in a fluid is in general a flower procefs. Yet are there many chemical mix« tures in which heat is given out as inftantaneoufly ; as in folutions of metals in acids, or in mixtures of eflential oils and acids, as of oil of cloves and acid of nitre. So the bruifed parts of an unripe apple become almofl inflantaneoufly fweet ; and if the chemico-animal procefs of digeftion be flopped for but a moment, as by fear, or even by voluntary erudation, a great quantity of air is generated, by the fermentation which inflantly fucceeds the flop of digeftion. By the experiments of Dr. Hales it appears, that an apple during fermentation gave up above fix hundred times its bulk of air ; and the materials in the flomach are fuch, and infuch actuation, as im- mediately to run into fermentation, when digeflion is impeded. As the blood paffes through the fmall veflels of the lungs, which connect the pulmonary artery and vein, it undergoes a change of colour from a dark to a light SECT. XXIII. 5. OF THE CIRCULATORY SYSTEM. 309 a light red : which may be termed a chemical change, as it is known to be effected by an admix- ture of oxygene, or vital air ; which, according to a difcoyery of Dr. Prieftley, pafles through the moid membranes, which conftitute the fides of thefe vef- fels. As the blocd pafles through the capillary vef- fels, and glands, which conned the aorta and its va^ rious branches with their correfpondent veins in the extremities of the body, it again lofes the bright red colour, and undergoes fome new combinations jn the glands or capillaries, in which the matter of heat is given out from the fecreted fluids. This pro- cefs therefore, as well as the procefs of refpiration, has fome analogy to combuflion, as the vital air or oxygene feems to become united to fome inflamma- ble bafe, and the matter of heat efcapes from the new acid, which is thus produced. V. After the blood has pafled thefe glands and capillaries and parted with whatever they chofe to take from it, the remainder is receive \ by the veins, which are a fet of blood-abforbing veflels in general correfponding with the ramifications of the arterial fyflem. At the extremity of the fine convolutions of the glands the arterial force ceafes ; this in ref- peft to the capillary veflels, which unite the extre- mities of the arteries with the commencement of the veins, is evident to the eye, on viewing the tail of a tadpole by means of a folar, or even by a common microfcope, for globules of blood are feen to endea- vour to pafs, and to return again and again, before they become abforbed by the mouths of the veins ; which returning of thefe globules evinces, that the arterial force behind them has ceafed. The veins are furnifhed with valves like the lymphatic abforbents; and the great trunks of the veins, and of the la&eals and lymphatics, join together before the ingrefs of their fluids into the left chamber of the heart ; both which OF THE CIRCULATORY SYSTEM. SECT. XXIH. 6. which evince that the blood in the veins, and the lymph and chyle in the lacteals and lymphatics, are carried on by a fimilar force; otherwife the ftream, which was propelled with a lefs power, could not enter the veflels, which contained the ftream pro- pelled with a greater power. From whence it ap- pears, that the veins are a fyftem of veflels abforbing blood, as the lacteals and lymphatics are a fyftem of veflels abforbing chyle and lymph. See Section XXVI. i. VI. The movements of their adapted fluids in the various veflels of the body are carried forwards by the actions of thofe veflels in confequence of two kinds of ftimulus, one of which may be compared to a pleafurable fenfationor defire inducing the veflel to feize, and, as it were, to fwallow the particles thus felected from the blood ; as is done by the mouths of the various glands, veins, and other abforbents, which may be called glandular appetency. The other kind of flimulus may be compared to difa- greeable fenfation or averfion, as when the heart has received the blood, and is ftimulated by it to pufh it forwards into the arteries ; the fame again ftimulates the arteries to contract, and carry forwards the blood to their extremities, the glands and capillaries. Thus the mefenteric veins abforb the blood from the intef- tines by glandular appetency, and carry it forward to the vena portarum ; which acting as an artery contracts itfelf by difagreeable flimulus, and pufhes it to its ramified extremities, the various glands, which conftitute the liver. It ieems probable, that at the beginning of the formation of thefe veflels in the embryon, an agree- able fenfation was in reality felt by the glands during fecretion, as is now felt in the act of fwallowing pa- latable food ; and that a difagreeable fenfation was originally felt by the heart from the diftention occa- fioned SECT. XXIII. 6. OF THE CIRCULATORY SYSTEM. 31 i fionedby the blood, or by its chemical flimulus; but that by habit thefe are all become irritative motions ; that is, fuch motions as do not affecl: the whole fyf- tem, except when the veffcls are difeafed by inflam- mation. SECT. OF THE SALIVA AND TEARS. SECT. XXiV. t» SECT. XXIV. OF TrfE SECRETIONS OF SALIVA, AND OF TEARS, AND OF THE LACRYMAL SACK. I. Secretion of fdl'rva increafed by mercury in the blood* i. By the food in the mouth. Drynefs of the mouth not from a deficiency of /diva. 2 By fenfiti've ideas. 3. By volition. 4. By di ft aft ef ul fiib fiances* It is fe crete d In a dilute and f aline ft ate. It then be- comes more vifcid. c. By ideas of d$afteful fub- ftances. 6. By naufea. 7. By aver/ton. 8. By catenation with Stimulating fubftances in the ear. IL i. Secretion of tears lefs injleep. From ftimula- iion of their excretory duel:. 2. Lacrymal fack is a gland. 3. Its ufes. 4. fears arefecreted when the nafal dud is ftimulated. 5. Or when it is excited by fenfation. 6. Or by volition, j. T/JC lacrymal fack can regurgitate its contents into the eye* 8. More tears are fecreted by ajjociation with the irritation of the nafal duel f the la:rymal fuck, than the puncla lacrymalia can imbibe. Of the gout in the liver and Jiomach. I. THE falival glands drink up a certain fluid from the circumfluent blood, and pour it into the mouth. rl hey are fometimes ftimulated into a&ion. by the blood, that furrounds their origin, or by fome part of that heterogeneous fluid : for when mercurial falts, or oxydes, are mixed with the blood, they fti- mulate thefe glands into unnatural exertions; and then an unufual quantity of faliva is feparated. As the faliva fecreted by thefe glands is mod wanted during the maftication of our food, it hap- pens, when the terminations of their du6ts in the mouth are ftimulated into adion, the falival glands themfelves SECT. XXIV. 2. 3-4- OF THE SALIVA AND TEARS. 31 j themfelves are brought into increafed aftion at the fame time by afibciation, and feparate a greater quantity of their juices from the blood ; in the fame manner as tears are produced in greater abundance during the ftimulus of the vapour of onions, or of any other acrid material in the eye. The faliva is thus naturally poured into the mouth only during the ftimulus of our food in maftication ; for when there is too great an exhalation of the mu- cilaginous fecretion from the membranes, which line the mouth, or too great an abforption of it, the mouth becomes dry, though there is no deficiency in the quantity of faliva ; as in thofe who fleep with their mouths open, and in fome fevers. 2. Though during the maftication of our natural food thefalival glands are excited into aclion by the ftimulus on their excretory duds, and a due quantity of faliva is feparated from the blood, and poured into the mouth; yet as this maftication of our food is always attended with a degree of pleafure ; and that pleafurable fenfation is alfo connected with our ideas of certain kinds of aliment : it follows, that when thefe ideas are reproduced, the pleafurable fen- fation arifes along with them, and the falival glands are excited into action, and fill the mouth with faliva from this fenfitive alTociation, as is frequently feen in dogs, who Haver at the fight of food. 3. We have alfo a voluntary power over the ac- tion of thefe falival glands, for we can at any time produce a flow of faliva into our mouth, and fpit out, or fwallow it at will. 4. If any very acrid material be held in the mouth, as the root of pyrethrum, or the leaves of tobacco, the falival glands areftimulated into ftronger action than is natural, and thence fecrete a much larger quantity of faliva ; which is at the fame time more vifcid than in its natural ftate ; becaufe the lympha- tics, that open their mouths into the duels of the falival OF THE SALIVA AND TEARS. SECT. XXIV. 5. & falival glands, and on the membranes, which line the mouth, are likewife ftimulated into ftronger action, and abforb the mofe liquid parts of the faliva with greater avidity ; and the remainder is left both in greater quantity and more vifcid. The increafed abforption in the mouth by fome flimulatin^ fubflar ces, which are called aftringents, as crab jiiice, is evident from the inftant drynefs produced in the mouth by a fmaii quantity of them, As the extremities of the glands are of exquifite tenuity, as appears by their difficulty of injection, it was neceffary for them to fecfete their fluids in a very dilute Rate ; and probably for the purpofe of fiimu- lating them into action, a quantity of neutral fait is likevvife fecreted or formed by the gland. This aqueous and ialine part of all fecreted fluids is again reabfcrbed into the habit. More than half of fome fecreted fluids is thus imbibed from the refervoirs, into which they are poured ; as in the urinary blad- der much more than half of what is fecreted by the kidneys becomes reabforbed by the lymphatics, which are thickly difperfed around the neck of theb adder* This feems to be the purpofe of the urinary bladders of tifh, as otherwife fuch a receptacle for the urine could have been of no ufe to an animal immerfed in water. 5. The idea of fubflances difagreeably acrid will alfo produce a quantity of faliva in the mouth ; as when we fmell very putrid vapours, we are induced to fpit out our faliva, as if fomething dilagreeable was actually upon our palates. 6, When difagreeable food in the ftomach produ- ces naufea, a flow of faliva is excited in the mouth by aflbciation ; as efforts to vomit are frequently produced by difagreeable drugs in the mouth by the 7. A Sfecr. XXiV. 2. OF THE SALIVA AND TEARS. 315 7. A preternatural flow of faliva is likevvife foiae- times occaiioncd by a difeafe of the voluntary power ; for if xve think about our faliva> and determine not to (wallow it, or not to fpit it out, an exertion is produced by the will, and more faliva is fecreted againft our wifll ; that is, by our averfion, which bears the fame analogy to defire, as pain does to4 pleafure ; as they are only modifications of the fame difpofitioh of the fenforium. See Clafs IV. 3. 2. i. 8. The quantity of faliva may alfo be increafed beyond what is natural, by the catenation of the motions of thefe glands with other motions, or feii- fations, as by an extraneous body in the ear; of which I have known an inflance; or by the applica- tion of ftizolobium, filiqua hirfuta, cowhage, to the feat of the parotis, as fome writers have affirmed. II. t. The lacrymal gland drinks up a certain, fluid from the circumfluent blood, and pours it oh the ball of the eye, on the upper part of the exter- nal cornet of the eyelids. Though it may perhaps be flimulated into the performance of its natural udlion by the blood, -which furrounds its origin, or by fome part of that heterogeneous fluid ; yet as the tears fecreted by this gland are more wanted at fome times than at others, its fecretion is variable, like that of the faliva above mentioned, and is chiefly produced when its excretory duel: is flimulated ; for in our common fleep there feems to be little or no fecretion of tears ; though they are occafionally produced by our fenfations in dreams. Thus when any extraneous material on the eye- ball, or the drynefs of the external covering of it, or the coldnefs of the air, or the acrimony of fome vapours, as of onions, Simulates the excretory duel: of the lacrymal gland, it difcharges its contents upon the ball ; a quicker fecretion takes place in the gland, and abundant tears fucceed, to moiiten, clean, and lubricate the eye, Thefe by frequent nictitation are VOL. I. Y diffufed 316 OF THE SAL1V4 AND TEARS SECT. XXfV. 2. 5. 4, difFufed over the whole ball, and as the external an- gle of the eye in winking is doled iboner than the internal angle, the tears are gradually driven foi- wards, and downwards from the lacrymal gland to the puncta lacrymalia. 2. The lacrymal fack, with its puncta lacrymalia, and its nafal duel, is a complete gland ; and is fm- gular in this refpect, that it neither derives its fluid from, nor difgorges it into the circulation. The fimplicity of the ftructure of this gland, and both the extremities of it being on the furfaceof the body, makes it well worthy our minuter obfervation ; as the actions of more intricate and concealed glands may be better underftood from their analogy to this, 3. This fimple gland confifts of two abforbing mouths^ a belly, and an excretory duel. As the tears are brought to the internal angle of the eyev thefe two mouths drink them up, being ftimula-ted into action by this fluid, which they abforb. The belly of the gland, or lacrymal fack, is thus filled, in which the faline part of the tears is abforbed, and when the other end of the gland, or nafal duel, is ftimulated by the drynefs, or pained by the coldnek of the air, or affected by any acrimonious duft o? vapour in the noftriis, it is excited into action toge- ther with the fack, and the tears are difgorged upon the membrane, which lines the noftriis ; where they ferve a fecond purpofe to moiften, clean, and lubri- cate the organ of fmeil. 4. Whea- the nafal duet of this gland-is ftimulated by any Very acrid material, as the powder of tobac- co, or volatile fpirits, it not only difgorges the con- tents of its belly or receptacle (the lacrymal fack;, and abforbs haftily all the fluid, that is ready for it in the corner of the eye ; but by the aifociation of its motions with thofe of the lacrymal gland, it excites that alfo into increafed action,- and a large flow of tears is poured into the eye* 5. Thir T.XXiV. 5.6.7.8. OF THE SALIVA AND TEARS. 317 5. This nafal duct is likewife excited into ftrong aelion by fenfitive ideas, as in grief, or joy, and then ulfo by its afibciations with the lacrymal gland it produces a great flow of tears without any external ilimulus ; as is more fully explained in Seel:. XVI. 8. on Inftindt. 6. There are fome, famous in the arts of exciting companion, who are faid to have acquired a volun- tary power of producing a flow of tears in the eye; which, from what has been faid in the fection on Inftincl: above mentioned, I fhould fufpect, is per- formed by acquiring a voluntary power over the aclion of this nafal duel. 7. There is another circumftance well worthy our attention, that when by any accident this nafal duel: is obftructed, the lacrymal fack, which is the belly or receptacle of this gland, by flight preflure of the finger is enabled to difgorge its contents again into the eye ; perhaps the bile in the fame manner, when the biliary duels are obtfru&ed, is returned into the blood by the veffels which fecrete it ? 8. A very important though minute occurrence muft here be obferved, that though the lacrymal gland is only excited into aclion, when we weep at a diftrefsful tale, by its aiTociation with this nafal duel, as is more fully explained in Seel. XVI. 8 ; yet the quantity of tears fecreted at once is more than the puncta lacrymalia can readily abforb ; which {hews that the motions occasioned by ajjociatiom are fre- quently more energetic than the original motions, by which they were occasioned. Which we (hall have occafion to mention hereafter, to illuftrate, why pains fre- quently exift in a part diflant from trre caufe of them, as in the other end of the urethra, when a ftone Simulates the neck of the bladder. And why in- flammations frequently arile in parts diftant from their caufe, as the gutta rolea of drinking people, from an inflamed liver. Ys The 318 OF THE SALIVA AND TEARS. SECT. The inflammation of a part is generally preceded by a torpor or quiefcence of it; if this exifts in any large congeries of glands, as in the liver, or any membranous paTt, as the ftomach, pain is produced and chiilinefs in confequence of the torpor of the vefiels. In this fituation fometimes an inflammation of the parts fucceeds the torpor ; at other times a diftant more fenfible part becomes inflamed ; whofe actions have previoufly been affociated with it ; and the torpor of the firft part ceafes. This I apprehend happens, when the gout of the foot fucceeds a pain ©f the biliary duet, or of the ftomach. Laftly, it fometimes happens, that the pain of torpor exifts without any confequent inflammation of the affected part, or of 'any diftant part aflbciated with it, as in the membranes about the temple and eye-brows in hemicrania, and in tfrofe pains, which occafion con- vulfions ; if this happens to gouty people, when k affects the liver, I fuppofe epileptic fits are produced ; and, when it affects the ftomach, death is the COTJ- fequence. In rhefe cafes the pulfe is weak, and the extremities cold, and fuch medicines as ftimulate the quiefcent parts into action, or which induce in'- flammation in them, or in any diftant parr, which is aflbciated with them, cures the prefent pain of torpor, and faves the patient. I have twice feen a gouty inflammation of the liver, attended with jaundice ; the patients after a few days were both of them affected with cold fits; like ague-fits, and their feet became affected with gout, and the inflammation of their livers cealed. It is probable, that the uneafy fenfations about the ftomach, and indigeftion which precedes gouty paroxyfms, are generally owing to torpor or flight inflammation of the liver, and biliary ducts ; but where great pain with continued ficknefs, wirh fssbls p«ulfe, and fearaticn of cold, affect rhe ftomaeihi SECT. XXIV. 8. OF THE SALIVA AND TEARS. 319 ftomach in patients debilitated by the gout, that it is a torpor of the flomach itfelf, and deftroys the patient from the great connexion of that vifcus with the vital organs. See Sed, XXV. 17. SEC 1\ 320 STOMACH AND INTESTINES. S&ct. XX\r, i % SECT. XXV. OF THE STOMACH AND INTESTINES. f. Of ^wallowing our food. Ruminating animals. %. Action of the Jiomaclf. 3. dttion of the inteftines. Irritative motions cvnnecltd with tbefe. 4. Effttft of repletion. '"$, Stronger aftion of the flomach and inteftines from more fiimulating food. 6. Their action inverted by ftill 'greater famuli. Or by difguftful ideas. Or by volition.' 7. Other glands ftrengthen or invert their motions by fympathy. '8. Vomiting performed by intervals, g. Inversion of the cutane- iotfs absorbents, i o. Increafed fecretion of bile and pancreatic juice. 1 1 . Jnverfion of the lacJeals. 1 2. And of the bile-duels. 13. Cafe of a cholera. 14. Further account of the in'verfion of lacieals* 15. Iliac pajjwns. Valve of the colon. 16. Cure of the iliac pajfion. 17. Pain' of gall-flone diftinguifoed from pain of tie ftomach. Gout of the Jlomach from torpor^ from inflammation. Intermitting pulfs owing to indigejiion. To ovcrdofe of foxglove. Weak pulfe from emetics. Death from a blow on the Jlomach. From gout of the Jlomach. i. THE throat, ftomach, and jnteflines, may be confidered as one great gland ; which like the lacry- rnal fack above mentioned, neither begins nor ends in the circulation. 'Though the act of mafticating our aliment belongs to the fenfitive clafs of motions, jfor the pleafure of its tafte iniduces the mufcles of the jaw into action ; yet the deglutition of it when malticated is generally, if not always, 'an irritative motion, occafioned by the application of the food already mafticated to the origin of the pharynx ; ' . XXV. 2. 3. STOMACH A*D INTESTINES, 3.21 in the fame manner as we often fwallow our fpit.tle without attending to it. The ruminating cbfs of animals have the power to invert the motion of their gullet, and of their fir (I ftomach, from the flimulus of this aliment, when it is a little further prepared ; as is their daily practice in chewing the cud ; and appears to the eye of any one, who attends to them, whilft they are employed in the fecond maftication of their food. 2. When our natural aliment arrives into the ftomach, this organ is ftimulated into its proper vermicular aftion ; which beginning at the upper orifice of it, and terminating at the lower one, gradually mixes together and pumes forwards the digefting materials into the inteltine beneath it. At the fame time the glands, that fupply the gaftric juices, which ,are neceffary to promote the chemical part of the procefs of digeftion, are ftimu- lated to difcharge their contained fluids, and to feparate a further fupply from the blood-veflels : and the lacleals or lymphatics, which open their mouths into the ftomach, are ftimulated into a&ion, and take up fome part of the digefting materials. 3. The remainder of thefe digefting materials is carried forvvards into the upper inteftines, and ftimulates them into their periftaltic motion fimilar to that of- the ftomach ; wljich continues gradually to mix the changing materials, and pafs them along through the valve of the colon to the excretory end &f this great gland, the fphincter ani. The digefting materials produce a flow of bile, and of pancreatic juice, as they pafs along the duo- denum, by ftimulating the excretory duels of the liver and pancreas, which terminate in that inte- ftine : and other branches of the abforbent or lym- phatic fyftem, called lacleals, are excited to drink up, as it pailes, thofe parts of the digefting mate- rials. 322 STOMACH AND INTESTINES. SECT. XXV. 4. 5. rials, that are proper for rheir purpofe, by its ftiniu- lus on their mouths. 4. When the ftomach and inteftines are thus filled with their proper food, not only the motions of the gaftric glands, the pancreas, liver, and lacteal veflels, are excited into a&ion ; but at the fame time the whole tribe of irritative motions are exerted with greater energy, a greater degree of warmth, colour, plumpnefs, and moiflure, is given to the ikin from the increafed action of thofe glands called capillary veifels ; pleafurable fenfation is ex- cited, the voluntary motions are lefs eafily exerted, and at length fufpended ; and fleep fucceeds, un- lefs it be prevented by the fHmulus of furrounding objects, or by voluntary exertion, or by an acqui- red habit, which was originally produced by one or other of thefe circufnftances, as is explained in Seel. XXI. on Drunkennefs. At this time alfo, as the blood-veflels become re- plete with chyle, more urine is feparated into the bladder, and lefs of it is reabforbed ; more mucus poured into the cellular membranes, and lefs of it jeabforbed : the pulfe becomes fuller and fofter, and in general quicker. The reafon why lefs urine and cellular mucus is abforbed after a full meal with fufficient drink is owing to the blood-veflels being fuller : hence one means to promote abforp- tion is to decreafe the refiftance by emptying the yeffels by venefedion. From this decreafed abforp- tion the urine becomes pale as well as copious, and the. ikin appears plump as well as florid. By daily repetition of thefe movements they all become connected together, and make a diurnal circle of irritative action, and if one of this chain be difturbed, the whole is liable to be put into dif- order. See Seft. XX. on Vertigo. 5. When the itomach and inteftines receive a quantity of food, whofe ftimulus is greater than ufual SECT. XXV. 6. STOMACH AND INTESTINES. 323 ufual, all their motions, and thofe of the glands and lymphatics, are itimu'ared into ftronger action than ufual, and perform their offices with greater vigour and in lefs time : Inch are the effects cf certain quantities of fpice or oi vinous fpirit. 6. But if the quantity or duration of thefe (timuii are Mill further increased, the ftomach and throat are (iimulated into a motion, whole direction is contrary to the natural one above defcribed ; and they regurgitate the materials, which they contain, iinltead of carrying them forwards. This retrograde motion of the (tomach may be compared to the firetchings of wearied limbs the contrary wav, and is well elucidated by the following experiment. Look earneftly for a minute or two on an area an inch Iquare of pink (ilk, placed in a ilrong light, the eye becomes fatigued, the colour becomes faint, and at length vaniihes, for the fatigued eye can no longer be itimulated into, direct motions ; then on doling the eye a green fpeclrum will appear in it, which is a colour directly contrary to pink, and which will appear and difappear repeatedly, like the efforts in vomiting. See Section XXIX i r. Hence all thole drugs* which by their bitter or aftringent (timulus increale the action of the ftomach, as camomile and white vitriol, if their quantity is increafed above a certain dole, become emetics. Thefe inverted motions of the ftomach and throat are generally produced from the fiimulus of unna- tural food, and are attended with the Jenfation of naufea or ficknefs : but as this fenfation is again connected with an idea of the diftafteful food, which induced it ; fo an idea of nauleous food will alfo fometimes excite the action of naufea ; and that give rife by affociation to the inverfion of the moti- ons of the itomach and throat. As fome, who have had horfe-flefh or dogs-fielh given them for beef 324 STOMACH AND INTESTINES. SECT. XXV. 7. 8. beef or mutton, are faid to have vomited many Jiours afterwards, when they have been told of the impofition. I have been told of a perfon, who had gained a voluntary command over thefe inverted motions of the ftomach and throat,' and fupported himfelf by exhibiting this curiofity to the public. At thefe exhibitions he fwallowed a pint of red rough goofe- berries, and a pint of white fmooth ones, brought them up in fmall parcels into his mouth, and re- ftored them feparately to the fpectators, who called for red or white as they pleafed, till the whole were re-delivered. 7.' At the fame time that thefe motions of the ftomach and throat are ftimulated into inversion, fome of .the other irritative motions, that had ac- quired more immediate connexions with the fto- mach, as thofe of the gaftric glands, are excited into ftronger action by this alTociation ; and fome other of thefe motions, which are more eafily ex- cited, as thofe of the gaftric lymphatics, are invert- ed by their aflbciation with the retrograde motions of the ftomach, and regurgitate their contents, and thus a greater quantity of mucus, and of lymph, or chyle, is poured into .the ftomach, and thrown up along with its contents. 8. Thefe inversions of the motion of the ftomach in vomiting are performed by intervals, for the fame reafon that many other motions are recipro- cally exerted and relaxed ; for during the time of exertion the ftimulus, or fenfation, which caufed this exertion, is not perceived : but begins to be perceived again, as foon as the exertion ceafes, and is fome time in again producing its effect. As explained in Seel. XXXiV. on Volition, where it is (hewn, that the contractions of the fibres, and the fenfation of pain, which pccafioned that exer- tion, cannot exift at the fame time. The exertion ceafes T.XXV.9. lo. ix. 12. STOMACH AND INTESTINES. 335 ceafes from another caufe alfo, which is the ex- hauftion of the fenforial power of the part, and theft? two caufes frequently operate together. 9. At the times of thefe inverted efforts of the ftomach not only the lymphatics, which open their mouths into the ftomach, but thofe of the fkin alfo, are for a time inverted ; for fweats are fornetimes pufhed put during the efforts of vomiting without an increafe of heat. 10. But if by a greater ftimulus the motions of the ftomach are inverted ftill more violently or more permanently, the duodenum has its periftaltic motions inverted at the fame time by their affocia- t'ion with thofe of the ftomach ; and the bile and pancreatic juice, which it contains, are by the in- verted motions brought up into the ftomach, and diicharged along with its contents; while a greater quantity of bile and pancreatic juice is poured into this inteftine; as the glands, that fecrete them, are by the^r affociation with the motions of the inteftine excited into ftronger action than ufual. 1 1 . The other inteftines are by affociation ex- cited into more powerful action, while the lympha- tics, that open their mouths into them, fuffer an inverfion of their motions correfponding with the lymphatics of the ftomach, and duodenum ; whicli with a part of the abundant fecretion of bile is carried downwards, and contributes both to ftimu- late the bowels, and to increafe the quantity of the evacuations. This inverfion of the motion of the lymphatics appears from the quantity of chyle, which comes away by (tools; which is otherwife abforbed as foon as produced, and by the immenfe quantity of thin fluid, which is evacuated along with it. 12. But if the ftimulus, which inverts the fto- mach, be ftill more powerful, or more permanent, it fornetimes happens, that the motions of the biliary glands, 3*6 STOMACH AND INTESTINES SECT. XXV. 13. 14. glands, and of their excretory duels, are at the fame time inverted, and regurgitate their contained bile into the blood veflels, as appears by the yellow colour of the fkin, and of the urine ; and it is probable the pancreatic fecretion may fuffer an in- yerfion at the fame time, though we have yet no raark by which this can be afcertained. 13. Mr. eat two putrid pigeons out of a cold pigeon-pye, and drank about a pint of beer and ale along with them, and immediately rode about five miles. He was then feized with vomit- ing, which was after a few periods fucceeded by purging ; thefe continued alternately for two hours ; and the purging continued by intervals for fix or eight hours longer. During this time he could not force himfelf to drink more than one pint in the whole ; this great 'inability to drink was owing to the naufea, or inverted motions of the flomach, which the voluntary exertion of fwallowing could feldom and with difficulty overcome; yet he dif- charged in the whole at leaft fix quarts ; whence came this quantity of liquid? Firft, the contents of die flomach were emitted, then of 'the duodenum, gall-bladder, and pancreas, by vomiting. After this the contents of the lower bowels, then the chyle, that was in , the lacleal veflels, and in the receptacle of chyle, was regurgitated into the intef- tines by a retrograde motion of thefe veflels. And afterwards the mucus depofited in the cellular mem- brane, and on the furface of all the other mem- branes, feems to have been abforbed ; and with the fluid abforded from the air to have been carried up their lefpe.ctive lymphatic branches by the increafed energy of their natural motions, and down the vifceral lymphatics, or lacleals, by the inverfion of their motions* 14. It may be difficult to invent experiments to demonstrate the truth of this inverfion of fome branches SECT. XXV. 15. STOMACH AND 1NESTINES. 327 branches of the abforbent fyftem, and increafect abforption of others, but the analogy of thefe vef- fels to the Intel; inal canal, and the fymptoms of many difeafes, render this opinion more probable than many other received opinions of the animal ceconomy. In the above inflance, after the yellow excrement was voided, the fluid ceafed to have any fmell, and appeared like curdled milk, and then a thinner fluid, and fome mucus, were evacuated ; did not thefe feera to partake of the chyle, of the mucous fluid from all the cells of the body, and laflly, of the atmofpheric moifture ? All thefe facts maybe eafily obferved by any one, who takes a brifk purge. 15. Where the (Hmulus on the ftomach, or on fome other part of the inteftinal canal, is ftill more permanent, not only the lacteal veflels, but the whole canal itfelf, becomes inverted from its aflb- ciations : this is the iliac paiTion, in which all tire fluids mentioned above are thrown up by tire mouth. At this time the valve in the colon, from the inverted motions of that bowel, and the in- verted action of this living valve, does not prevent the regurgitation of its contents. The ftructure of this valve may be reprefented by a flexile leathern pipe (landing up from the bot- tom of a veflel of water : its fides collapfe by the preiTure of the ambient fluid, as a fmait part of that fluid paries through it ; but if it has a living power, and by its inverted action keeps itfelf open, it be- comes like a rigid pipe, and will admit the whole liquid to pafs. See Sect. XXIX. 2. 5. In this cafe the patient is averfe to drink, from the conftant inverfion of the motions of the fto- mach, and yet many quarts are daily ejected from f'-.e ftomach, which at length find! of excrement, and STOMACH AND INTESTINES. SECT. XXV. 15. and at lafl feem to be only a thin mucilaginous or aqueous liquor. From whence is it poilible, that this great quan- tity of fluid for many fucceflive days can be fupplied^ after the cells of the body have given up their fluids, but from the atmofphere? When the cuta- neous branch of abforbents ads with unnatural ftrength, it is probable the inteftinal branch has its motions inverted, and thus a fluid is fupplied with- out entering the arterial fyfteffi. Could oiling or painting the fkin give a check to this difeafe ? So when the ftomach has its motions inverted? the lymphatics of the .ftomach, which are mod ftridly aflbciated with it, invert their motions at the fame time. But the more diftant branches of lymphatics, which are lefs ftrictly aflbciated with it, a£t with ihcreafed energy ; a$ the cutaneous lym- phatics in the cholera, or iliac paflion, above de- fcribed. And other irritative motions become de- creafed, as the pulfations of the arteries, from the extra-derivation or exhauftion of the fenforial power. Sometimes when ftronger vomiting takes placed the more- diftant branches of the lymphatic fyftem invert their motions with thofe of the ftomach, and loofe (tools are produced, and cold fweats. S6 when the lacteals have their motions inverted; is during the operation of ftfong purges, the urinary and cutaneous abforbents have their mo- tions increafed to fupply the want of fluid in the blood, as in great thifft ; but after a meal with fufficient potation the urine is pa:le, that is, the arinary abforbents act weakly, no fupply of water being wanted for the blood. And when the intefti- nal abforbents acl: too violently, as when too great quantities of fluid have been drank, the urinary abibrbents invert their motions to carry off the fuperfluity Seer. XXV. 16. 17. STOMACH AND INTESTINES. 32? fuperfluity, which is a new circumftance of aflbcia- tion, and a temporary diabetes fupervenes. 1 6. I have had the oportunity of feeing four patients in the iliac paflion, where the ejected ma- terial fmelled and looked like excrement. Two of thefe were fo exhaufted at the time I faw them, that more blood could not be taken from them, and as their pain had ceafed, and they continued to vomit up every thing which they drank, I fuf- pecled that a mortification of the bowel had already taken place, and as they were both women advanced in life, and a mortification is produced with lefs preceding pain in old and weak people, thefe both died. The other two, who were both young men, had (till pain and flrength fufficient for further venefection, and they neither of them had any appearance of hernia, both recovered by repeated bleeding, and a fcruple of calomel given to one, and half a dram to the other, in very fmall pills : the ufual means of clyfters, and purges joined with opiates, had been in vain attempted. I have thought an ounce or two of crude mercury in lefs violent . difeafes of this kind has been of ufe, by contribu- ting to reftore its natural motion to fome part of the inteftinal canal, either by its weight or flimulus; and that hence the whole tube recovered its ufual aifociations of progreflive periftaltic motion I have in three cafes feen crude mercury given in fmall dofes, as one or two ounces twice a day, have great effect in (topping pertinacious vomitings. 17. Befides the affections above defcribed, the ftomach is liable, like many other membranes of the body, to torpor without confequent inflamma- tion : as happens to the membranes about the headj in fome cafes of hemicrania, or in general head- ach. This torpor of the itomach is attended with indigeftion, and confequent flatulency, and with pain, which is ufualiy called the cramp of the fto- 330 STOMACH AND INTESTINES. SECT. XXV. 17" rnach, and is relievable by aromatics, eficntial oils, alcohol, or opium. The intruiion of a gall-done into the commort bile-duel from the gall-bladder -is fometimes mif- taken for a pain of the ftomach, as neither of them are attended with fevef ; but in the palfage of a gall-fione, the pain is confined to a lefs fpace, -which is exactly where the common bile-duel enters the .duodenum, as explained in Section XXX. 3. Whereas in this gaftrodynia the pain is diffufed over the whole ftomach ; and, like other difeafes from torpor,' the pulfe is weaker, and the extremities coktef, and the general debility greater, than in the paffage of a gall ftone ; for-in the former the debility is the confequence of the pain, in the latter it is the caufe of it. Though the firft fits of the gout, I believe, com- mence with a torpor of the liver ; and the ball of the toe becomes inflamed inftead of the mem- branes of the liver in confequence of this torpor, as a coryza or catarrh frequently fucceeds a long cxpofure of the feet to cold, as in fnow, or on a moid brick-floor; yet in old or exhaufteJ conftf- tutions, which have been long habituated to its attacks, it fometimes commences with a torpor of the llomach, and is transferable to every membrance of the body. When the gout begins with torpor of the iiomach, a painful feniation of cold occurs, which the patient compares to ice, with weak pulfe, cold extre- mities, and ficknefs ; this in its flighter degree is re- lievable by fpice, wine, or opium; in its greater degree it is fucceeded by fudden death, which is owing to the fytnpathy of the ftomach with the heart, as explained below. if the ftomach becomes inflamed in confequence of this gouty torpor of it, or in confequence of its fympathy with fome other part, the danger is lefs. A ficknefs and vomiting continues many days, or evea if CT. XXV. 17. STOMACH AND INTESTINES. 331 even week?, the flomach rejecting every thing fli- niulant, even opium or alcohol, together with much vifcicl mucus ; till the inflammation at length ceafes, as happens when other membranes, as thofe of the joints, are the feat of gouty inflammation ; as obferved in Sett. XXIV. 2. 8. The fympathy or aflbciation of motions, between thofe of the flomach and thofe of the heart, are evinced in many difeafes. Firfl, many people are occafionally affected with an intermiffion of their pulfe for a few days, which then ceafes again. In this cafe there is a (top of the motion of the heart, and at the fame time a tendency to eructation from the flomach. As foon as the patient feels a ten- dency to the intermiffion of the motion of his heart, if he voluntarily brings up wind from his flomach, the flop of the heart does not occur. From hence I conclude that the flop of digeflion is the primary difeafe ; and that air is inflantly generated from the aliment, which begins to ferment, if the digeflive procefs is impeded for a moment, (fee Sect. XX1IL 4.) ; and that the flop of the heart is in confe- quence of the aflbciation of the motions of thefe vifcera, as explained in Sect. XXXV. i. 4. ; but if the little air, which is inflantly generated during the temporary rorpor of the flomach, be evacuated, the digeflion recommences, and the temporary torpor of the heart does not follow. One patient, \vhom I lately faw, and who had been five or fix days much troubled with this intermiffion of a pul- fation of his heart, and who had hemicram*a with fome fever, was immediately relieved from them all by lofing ten ounces of blood, which had what is termed an inflammatory crud on it. Another inftance of this aflbciation between the motions of the flomach and heart is evinced by the exhibition of an over dofe of foxglove, which in- duces an inceflant vomiting, which is attended with VOL. I. Z very STOMACH AND INTESTINES. SECT. XXV. 17. very flow, and fometimes intermitting pulfe. — Which continues in fpite of the exhibition of wine and opium for two or three days. To the fame afibciation muft be afcribed the weak pulfe, which conftantly attends the exhibition of emetics during their operation. And alfo the fudden deaths, which have been occafioned in boxing by a blow on the ftomach ; and laftly, the fudden death of thofe, who have been long debilitated by the gout, from the torpor of the ftomach. See Seel:, XXV, i. 4* SECT. S*CT. XXVI. i. OF GLANDS AND MEMBRANES. 3^ SECT. XXVI. OF THE CAPILLARY GLANDS AND MEMBRANES* I. i . The capillary veflels are glands. 2. Their excre* tory duels. Experiments on the mucus of the intef* tines , abdomen , cellular membrane, and on the humours of the eye. 3. Scurf on the head, cough, catarrh, diarrhoea, gonorrhoea. 4. Rheitmatifm. Gout. Leprofy. II. i. The moft minute membranes are unorganized. 2. Larger membranes are com- pofed of the duels of the capillaries, and the mouths of the abf or bents. 3. Mucilaginous fluid is fecreted on their furf aces. III. Three kinds of Rheumatifm. 1. i. THE capillary veflels are like all the other- glands except the abforbent fyftem, inafmuch as they receive blood from the arteries, feparate a fluid from it, and return the remainder by the veins. 2. This feries of glands is of the moft extenfive ufe, as their excretory duels open on the whole ex- ternal fkin forming its perfpirative pores, and on the internal furfaces of every cavity of the body. Their fecretion on the Ikin is termed infenfibie perfpira- tion, which in health is in part reabforbed by the mouths of the lymphatics, and in part evaporated in the air ; the fecretion on the membranes, which line the larger cavities of the body, which have ex- ternal openings, as the mouth and inteftinal canal, is termed mucus, but is not however coagulable by heat ; and the fecretion of the membranes of thofe cavities of the body, which have no external openings, is called lymph or water, as in the cavi- ties of the cellular membrane, and of the abdo- men ; this lymph however is coagulable by the heat of boiling water. Some mucus nearly as vifcid as Z 2 the 334 OF GLANDS AND MEMBRANES. SECT. XXV? s. the white of egg, which was difcharged by ftool, did not coagulate, though I evaporated it to one- fourth of the quantity, nor did the aqueous and vitreous humours of a fheep's eye coagulate by the like experiment : but the ferofity from an anafar- cous leg, and that from the abdomen of a dropfical perfon, and the cryflalline humour of a fheep's eye, coagulated in the fame heat. 3. When any of thefe capillary glands are Simu- lated into greater irritative actions, than Is natural, they fecrete a more copious material ; and as the mouths of the abforberit fyftem, which open in their vicinity, are at the fame time ftimulated into greater aclion, the thinner and, more faline part of the fecreted fluid is taken up again ; and the re- mainder is not only more copious but alfo more vifcid than natural. This is more or lefs trouble- fome or noxious according to the importance of the functions of the part affected : on the Ikin and bronchia, where this fecretion ought naturally to evaporate, it becomes fo vifcid as to adhere to the membrane ; on the tongue it forms a pellicle* which can with difficulty be feraped off; produces the fcurf on the heads of many people j and the mucus, which is fpit up by others in coughing. OR the noftrils and fauces, when the fecretion of thefe capillary glands is increafed, it is termed fimple catarrh ; when in the inteftines, a mucous diarrhoea -9 and in the urethra, or vagina, it has the name of gonorrhoea, or fluor albus. 4. When thefe capillary glands become inflamed, a (till more vifcid or even cretaceous humour is produced upon the furfaces of the membranes, which b the caufe or the effect of rheumatifm, gout, leprofy, and of hard tumours of the legs, which generally termed fcorbutic j all which will ¥e treated of hereafter. II. i. The SECT. XXVI. 2. OF GLANDS AND MEMBRANES. 335 II. r. The whole fur face of the body, with all its cavities and contents, are covered with mem- brane. It lines every vefiel, forms every cell, and binds together all the mufcular and perhaps the o(Teo.us fibres of the body ; and is itfelf therefore probably a fimpler fubftance than thofe fibres. And as the containing vefTels of the body from the larged to the lead are thus lined and connected with membranes, it follows that thefe membranes themfelves confided of unorganized materials. For however fmall we may conceive the diame- ters of the minuted vefTels of the body, which efcape our eyes and glafles, yet thefe vefleis mud coniid of coats or fides, which are made up of an unorganized material, and which are probably pro- duced from a gluten, which hardens after its pro- duction, like the filk or web of caterpillars and fpiders. Of this ntaterial confid the membranes, which line the fhells of eggs, and the (hell itfelf, both which are unorganized, and, are formed from, mucus, which hardens after it is formed, either by the abforption of its more fluid part, or by its uni- ting with forne part of the atmofphere. Such is alfo the production of the fhelis of fnails, and of ihell-nfh, and 1 fuppole of the enamel of the teeth. 2. But though the membrane?, that compofe the fides of the mod minute velTels, are in truth unor- ganized materials, yet the larger membranes, which are perceptible to the eye, feem to be compofed of an intertexture of the mouths of the abforbent fydem, and of the excretory du&s of the capilla- ries, with their concomitant arteries, veins, ?Uld nerves: and from this conftruction it is evident, that thefe membranes mud poiTefs great irritability to peculiar dimuli, though they are incapable of any motions, that are vifible to the naked eye : daily experience mews us, that in their infla- $36 OF QLANDS AND MEMBRANES. SLCT. XXVI. 3. jned ftate they have the greateft fenfibility to pain, as in the pleurify and paronychia. 3. On all thefe membranes a mucilaginous or aqueous fluid is fecreted, which moiftens and lubri- cates their furfaces, as was explained in Section XXIII. 2, Some have doubted, whether this mu- cus is feparated from the blood by an appropriated fet of glands, or exudes through the membranes, or is an abrafion or deftruction of the furface of the membrane itfelf, which is continually repaired on the other fide of it, but the great -analogy between the capillary veflels, and the other glands, counte- nances the former opinion ; and evinces, that thefe capillaries are the glands, that fecrete it ; to which \ve mutt add, that the blood in patting thefe capil- lary veflels undergoes a change in its colour from florid to purple, and gives out a quantity of heat ; from whence, as in other glands, we muft conclude that fomething is fecreted 'from it. III. The feat of rheumatiirn is in the membranes, or upon them ; but there are three very diftinct dif- eafes, which commonly are confounded under this name. Firft, when a membrane becomes affected with torpor, or inactivity of the veflels which com- pofe it, pain and coldneis fucceed, as in J:he hemi- crania, and oiher head-achs, which are generally tefmed nervous rheumatifm ; they exift whether the part be at reft or in motion, and are generally attended with other marks of debility. Another rheumatifm is faid to exift, when inflam- mation and fweliing, as well as pain, affect fome of the membranes of the joints, as of the ancles, wrifts, knees, elbows, and fometimes of the ribs. This is accompanie4 with fever, is analogous to pleurify and other inflammations, and is termed the pcute rheumatifm. A third difeafe is called chronic rheumatifm, is d$inguiJhed from that firft mentioned, as JB SECT. XXVI. 3 OF GLANDS AND MEMBRANES. 337 in this the pain only affects the patient during the motion of the part, and from the fecond kind of rheumatifm above defcribed, as it is not attended with quick pulfe or inflammation. It is generally believed to fucoeed the acute rheumatifm of the fame p^rt, and that fome coagulable lymph, or cre- taceous, or calculous material, has been left on the membrane ; which gives pain, when the mufcles move over it, as fome extraneous body would do, which was too infoluble to be abforbed. Hence there is an analogy between the chronic rheuma- tifm and the difeafes which produce gravel or gout- ftones ; and it may perhaps receive relief from the fame remedies, fuch as aerated fal foda. SECT. 333 OF HEMORRHAGES. S|CT. XXVII. t- SECT. XXVII. Of HAEMORRHAGES. I. The 'veins are abforbent vejjeh. i. Hemorrhage* from inflammation. Cafe of hemorrhage from the kidney cured by cold bathing. Cafe of hemorrhage from the nofe cured by cqld immerfion. II. Hemorr- hage from venous paralyfis. Of Piles. Black Jlooh. Petecbitf. 'Consumption. Scurvy of the lungs* Blacknefs of the face and eyes in epileptic Jits. Cure of hemorrhages from venous inability. I. AS the imbibing mouths of the abforbent fyf- tern already defcribed open on the furface, and into the larger cavities of the body, fo there is another fyftem of abforbent veflels, which are not common- ly elteemed fuch, I mean the veins, which take up the blood from the various glands and capillaries, after their proper fluids or fecretions have been feparated from it. The veins referable the other abforbent vefTels ; as the prcgreilion of their contents is carried on in the fame manner in both, they alike abforb their appropriated fluids, and have valves to prevent its regurgitation by the accidents of mechanical vio- lence. This appears firft, beccaufe there is no pul- fation in the very beginnings of the veins, as is>feen by microfcopes ; which muft happen, if the blood "was carried into them by the actions of the arteries. For though the concurrence of various venous ,C reams of blood from different diftances muft pre- vent any pulfation in the larger branches, yet in the very beginnings of ail thefe branches a pulfation rhuft SECT. XXVII. i. OF HAEMORRHAGES. 359 mud unavoidably exift, if the circulation in them was owing to the intermitted force of the arteries. Secondly, the venous abforpdon of blood from the penis, and from the teats of female animals after their erection, is ftill more fimilar to the lymphatic abforption, as it is previoufly poured into cells, where all arterial impulfe muft ceafe. There is an experiment, which feems to evince this venous abforption, which confifts in the exter- nal application of a ftimulus to the lips, as of vine- gar, by which they become inftantly pale, that is, the bibulous mouths of the veins by this ftimulus are excited to abforb the blood fader, than it can be fupplied by the ufual arterial exertion. See Sed. XXIII. 5. There are two kinds of haemorrhages frequent in difeafes, one is where the glandular or capillary action is too powerfully exerted, and propels the blood forwards more hafUly, than the veins can abforb it; and the other is, where the abforbent power of the veins is diminifhed, or a branch of them is become totally paralytic. The former of thefe cafes is known by the heat of the part, and the general fever or inflammation that accompanies the haemorrhage. An haemorr- hage from the nofe or from the lungs is ibmetimes a crilis of inflammatory difeales, as of the hepatitis and gout, and generally ceafes fpontaneoufly, when the veflels are confiderably emptied. Sometimes the haemorrhage recurs by daily periods accompa- nying the hot fits of fever, and ceafing in the cold fits, or in the intermiffions ; this is to be cured by removing the febrile paroxyfms, which will by treated of in their place. Otherwife it is cured by venefe&ion, by the internal or external preparations of lead, or by the application of cold, with an ab- ftemious diet, and diluting liquids, like other in- flammations. 340 OF HEMORRHAGES. SECT. XXVII. i . flammations. Which by inducing a quiefcence on thofe glandular parts, that are affected, prevents a greater quantity of blood from being protruded forwards, than the veins are capable of abfprb- ing. Mr. B had an hemorrhage from his kid- ney, and parted with not lefs than a pint of blood a day (by conjecture) along with his urine for above a fortnight : venefedtions, mucilages, balfams, pre- parations of lead, the bark, alum, and dragon's blood, opiates, with a large blifter on his loins, •were Separately tried, in large dofes, to no pur- pofe. He was then directed to bathe in a cold fpring up to the middle of his body only, the upper part being covered, and the haemorrhage diminifhed at the firft, and ceafed at the fecond im- merfion. In this cafe the external capillaries were rendered quiefcent by the coldnefs of the water, and thence a lefs quantity of blood was circulated through them ; and the internal capillaries, or other glands, became quiefcent from their irritative aflbciations with the external ones ; and the hemorrhage was (topped a fufficient time for the ruptured veflels to contract their apertures, or for the blood in thofe apertures to coagulate. Mrs. K had a continued haemorrhage from her nofe for fome days ; the ruptured veflel was not to be reached by plugs up the noftrils, and the fen- fibility of her fauces was fuch that nothing could be borne behind the uvula. After repeated vene- feftion, and other common applications, (he was directed Jo immerfe her whole head into a pail of water, which was made colder by the addition of feveral handfuls of fait, and the haemorrhage im- mediately ceafed, and returned no more; but her pulfe continued hard, and (he was neceffita- SECT. XXVII. 2. OF HEMORRHAGES. 34, ted to lofe blood from the arm on the fticceeding day. Query, might not the cold bath inftantly (lop hemorrhages from the lungs in inflammatory cafes? — for the fhortnefs of breath of thofe who go fud- denly into cold water, is not owing to the accumu- lation of blood in the lungs, but to the quiefcence of the pulmonary capillaries from aflbciation, as explained in Seclion XXXII. 3. 2. II. The other kind of hemorrhage is known from its being attended with a weak pulfe, and other fymptoms of general debility, and very fre- quently occurs in thofe, who have difeafed livers, owing to intemperance in the ufe of fermented liquors. Thefe conftitutions are (hewn to be lia- ble to paralyfis of the lymphatic abforbents, pro- ducing the various kinds of dropfies in Section XXIX. 5. Now if any branch of the venous fyf- tem lofes its power of abforption, the part fwells, and at length burfts and difchargesr the blood, which the capillaries or other glands circulate through them. It fometimes happens that the large external veins ofvthe legs burfl, and effufe their blood; but this occurs mod frequently in the veins of the inteftines, as the vena portarum is liable to fuffer from a fchir- rus of the liver oppofmg the progreffion of the blood, which is abforbed from the inteftines. Hence the piles are a fymptom of hepatic obftruc- tion, and hence the copious difcharges downwards or upwards of a black material, which has been called melancholia, or black bile ; but is no other than the blood, which is probably difcharged from the veins of the inteftines. J. F. Meckel, in his Experimenta de Finibus Vaforum, publifhed at Berlin, 1772, mentions his difcovery of a communication of a lymphatic veflel -with 34* OF HAEMORRHAGES, SECT. XXV] 1. 2. with the gaftric branch of the vena portarum. It is pofiible, that when the motion of the lymphatic becomes retrograde in fome difeafes, that blood may obtain a pafTage into it, where it analtomofes with the vein, and thus be poured into the in- teftines. A difcharge of blood with the urine fome- times attends diabetes, and may have its fource in the fame manner. Mr. A , who had been a hard drinker, and had the gutta rofacea on his face and bread:, after a ftroke of the palfy voided near a quart of a black vifcid material by (tool : on diluting it with water it did not become yellow, as it muft have done if it had been infpiffated bile, but continued black like the grounds of coffee. But any other part of the venous fyftem may be- come quiefcent or totally paralytic as well as the veins of the inteftines : all which occur more fre- quently in thofe who have difeafed livers, than in any others. Hence troublefome bleedings of the nofe, or from the lungs with a weak pulfe ; henee haemorrhages from the kidneys, too great menftru- ation ; and hence the oozing of blood from every part of the body, and the petechias in thofe fevers, which are termed putrid, and which is erroneouily afcribed to the thinnefs of the blood : for the blood In inflammatory difeafes is equally tiuid before it coagulates in the cold air. Is not that hereditary confumption, which occurs chiefly in dark-eyed people about the age of twenty, and commences with flight pulmonary haemorrhages without fever, a difeafe of this kind ? — Thefe hse- morrhages frequently begin during fleep, when the irritability of the lungs is not fufficient in thefe patients to carry on the circulation without the ailillance of volition ; for in our waking hours, the motions ot the lungs are in part voluntary, efpeci- allv . XXVII. 2. OF HEMORRHAGES. 345 ally if any difficulty of breathing renders the efforts of volition neceiTary. See Clafs I. 2. i. 3. and Clafs HI. 2. i. 12. Another fpecies of pulmonary confumption which feems more certainly of fcro- phulous origin is defcribed in the next Section, No. 2. I have feen two cafes of women, of about forty years of age, both of whom were feized with quick weak pulfe, with difficult refpiration, and who fpit up by coughing much vifcid mucus mixed with dark coloured blood. They had both large vibices on their limbs, and petechias ; in one the feet were in danger of mortification, in the other the legs were cedematous. To relieve the difficult refpiration, about fix ounces of blood were taken from one of them, which to my furprife was fizy, like inflamed blood : they had both palpitations or unequal pulfa- tions of the heart. They continued four or five weeks with pale and bloated countenances, and did not ceafe fpitting phlegm mixed with black blood, and the pulfe feldom flower than 1 30 or 135 in a minute. This blood, from its dark colour, and from the many vibices and petechise, feems to have been venous blood ; the quieknefs of the pulfe, and the irregularity of the motion of the heart, are to be afcribed to debility of that part of the fyftem ; as the extravafation of blood originated from the defed of venous abforption. The approximation of thefe two cafes to fea-fcurvy is peculiar, and may allow them to be called fcorbutus pulmonalis. Had thefe been younger fubjeds, and the paralyfis of the veins had only affected the lungs, it is pro- bable the difeafe would have been a pulmonary con- fumption. Lafl week I faw a gentleman of Birmingham, who had for ten days laboured under great palpi- tation of his heart, which was fo diftinctly felt by the $44 OF HAEMORRHAGE! SECT, xxvif. & the hand* as to difcountenance the idea of there being a fluid in the pericardium. He frequently fpit up mucus ftained with dark coloured blood, his pulfe very unequal and very weak, with cold hands and nofe. He could not lie down at all, and for about ten days paft could not fleep a minute toge- ther, but waked perpetually with great uneafinefs0 Gould thofe fymptoms be owing to very extenfive adhefioris of the lungs ? or is this a fcofbutus pul- monalis ? After a few days he fuddenly got fo much better as to be able to fleep many hours at a time by the ufe of one grain of powder of foxglove twice a day, and a grain of opium at night. .After a few days longer, the bark was exhibited, and the opium continued with fome wine ; and the palpi- tations of his heart became much relieved, and he recovered his ufual degree of health, but died fud- denly fome months afterwards. In epileptic fits the patients frequently become black in the face, from the temporary paralyfis of the venous fyftem of this part. I have known two inftances where the blacknefs has continued many days. Mr. P , who had drank intemperately? was feized with the epilepfy when he was in his fortieth year ; in one of thefe fits the white part of bis eyes was left totally black with effufed blood -y which was attended with no pain or heat, and was in a few weeks gradually abforbed, changing colour as is ufual with vibices from bruifes. The haemorrhages produced from the inability of the veins to abforb the refluent blood, is cured by opium, the preparations of fteel, lead, the bark, \-itriolic acid, arid blifters; but thefe have the effect with much more certainty, if a venefe&ion to a few ounces, and a moderate cathartic with four or fix grains of calomel be premifed, where the patient is SECT. XXVIII. 2. PARALYSIS OF ABSORBENTS. 34$ is not already too much debilitated ; as one great means of promoting the abforption of any fluid confifts in previoufly emptying the veflels, which are to receive it. SECTJ 346 PARALYSIS OF ABSORBENTS. SECT. XXVIII. ;* SECT. XXVIII. OF THE PARALYSIS OF THE ABSORBENT SYSTEM. I. Paralyfis of the latteals^ atrophy. DiJIafte to animal food. II. Caufeofdropfy. Caufe of herpes. Scro- phuia. Mefentetic confumption. Pulimnary con- JumptioK* Why ulcers in the lungs are fo difficult to heal. THE term paralyfis has generally been ufed to cxprefs the lofs of voluntary motion, as in the hemi- plagia, but may with equal propriety be applied to exprefs the difobediency of the mufcular fibres to the other kinds of ilimulus ; as to thofe of irritation or fenfation. 1. There is a fpecies of atrophy, which has not been well underftood ; when the abforbent vefTels of the ftomach and inteftines have been long inured to the ftimulus of too much fpirituous liquor, they at length, either by the too fudden omiflion of fer- mented or fpirituous potation, or from the gradual decay of nature, become in a certain degree para- lytic ; now it is obfefved in the larger mufcles of the body, when one fide is paralytic, the other is more frequently in motion, owing to the lefs ex- penditure of fenforial power in the paralytic limbs ; fo in this cafe the other part of the abforbent fyflem acls with greater force, or with greater perfeve- rance, in confequence of the paralyfis of the lac- fleais ^ and the body becomes greatly emaciated in a fmall time. I have feen feveral . patients in this difeafe, of which the following are the circumflances. i . They were men of about fifty years of age, and had lived freely in refped to fermented liquors. 2. They loft feet. XXVIII. 2. PARALYSIS OF ABSORBENTS. 347 loft their appetite to animal food. 3. They became fuddenly emaciated to a great degree. 4. Their fkins were dry and rough. 5. They coughed and expectorated with difficulty a vifcid phlegm. 6- The membrane of the tongue was dry and red, and lia- ble to become ulcerous. The inability to digeft animal food, and the con- fequent diftafte to it, generally precedes the dropfy, and other difeafes, which originate from fpirituous potation. I fuppofe when the ftomach becomes in- irritable, that there is at the fame time a deficiency of gaftric acid ; hence milk feldom agrees with thefe patients, unlefs it be previoufly curdled, as they have not fufficient gaftric acid to curdle it; and hence vegetable food, which is itfelf acefcent, will agree with their flomachs longer than animal food, which requires more of the gaftric acid for its digeftion. In this difeafe the fkiii is dry from the increafed abforption of the cutaneous lymphatics, the fat is. abforbed from the increafed abforption of the cellu- lar lymphatics, the mucus of the lungs is too vifcid to be eafily fpit up by the increafed abforption. of the thinner parts of it, the membrana fneideriana becomes dry, covered with hardened mucus, and at length becomes inflamed and full of apthas, and either thefe floughs, or pulmonary ulcers, terminate the fcene. II. The immediate caufe of dropfy is the para- lyfis of fome other branches of the abforbent fyftem, which are called lymphatics, and which open into the larger cavities of the body, or into the cells of the cellular membrane ; whence thofe cavities or cells become diftended with the fluid, which is hourly fecreted into them for the purpofe of lubri- cating their furfaces. As is more fully explained in No. 5. of the next Section, VOL. I. A a As 348 PARALYSIS OF ABSOREENTS. SECT. XXVIII. *• As thofe lymphatic veffels confift generally of a long neck or mouth, which drinks up its appropri- ated fluid, and of a conglobate gland, in which this fluid undergoes fome change, it happens, that feme- times the mouth of the lymphatic, and fometimes the belly or glandular part of it, becomes totally or partially paralytic. In the former cafe, where the mouths of the cutaneous lymphatics become torpid or quiefcent, the fluid fecreted on the (kin ceafes to be abforbed, and erodes the (kin by its faline acri- mony, and produces eruptions termed herpes, the difcharge from which is as fait, as the tears, which are fecreted too faft to be reabforbed, as in grief, or when the pun&a lacrymalia are obftrufted, and which running down the cheek redden and inflame the fkin. When the mouths of the lymphatics, which open on the mucous membrane of the noftrifs, become torpid, as on walking into the air in a frofty morn- ing; the mucus, which continues to be fecreted, has not its aqueous and faline part reabforbed, which running over the upper lip inflames it, and has a fait tafte, if it falls on the tongue. When the belly, or glandular part of thefe lym- phatics, becomes torpid, the fluid abforbed by its mouth ftagnates, and forms a tumour in the gland. This difeafe is called the fcrophula. If thefe glands fuppurate externally, they gradually heat, as tbofe of the neck ; if they fuppurate without an opening on the external habit, as the mefenteric glands, a he&ic fever enfues, which deftroys the patient j if they fuppurate in the lungs, a pulmonary confump- tion enfues, which is believed thus to differ from that deferibed in the preceding Section, in refpect to its feat or proximate caufe. It is remarkable, that matter produced by fup- puration will 'He concealed in the body many weeks, or even months, without producing hectic fever ; but SECT. XXVIII; 2. PARALYSIS OF ABSORBEN FS. 349 but as foon as the wound is opened, fo as to admit air to the fur face of the ulcer, a he&ic fever fuper* venes, even in very few hours, which is probably owing to the azotic part of the atmofphere rather than to the oxygene ; becaufe thofe medicines* which contain much oxygene, as the calces or bxydes of metals, externally applied, greatly con- tribute to heal ulcers, of thefe are the folutions of lead and mercury, and copper in acids, or their precipitates. Hence when wounds are to be healed by the firft intention, as it is called^ it is neceffary carefully to exclude the air from them. Hence we have one caufe, which prevents pulmonary ulcers from heal- ing, which is their being perpetually expofed to the air. Both the dark-eyed patients, which are affe&ed with pulmonary ulcers from dificient venous abforp- tion, as defcribed iri Section XXVII. 2. and the light-eyed patients from deficient lymphatic abforp« tion, which we are now treating of, have generally large apertures of the iris ; thefe large pupils of the eyes are a common mark of want of irritability; and it generally happens, that an increafe of fenfi- bility, that is, of motions in confequence of fenfa- -tion, attends thefe conftitutions. See Seel. XXXI. 2. Whence inflammations may occur in thefe front ftagnated fluids more frequently than in thofe con- ftitutions, which poffsfs more irritability and lefs fenfibility. Great expectations in refpect to the cure of con- fumptions, as well as of many other difeafes, are produced by the very ingenious exertions of DR, BEDDOES; who has eftablifhed an apparatus for breathing various mixtures of airs or gaffes, at the hot-wells near Briftol, which well deferves the at- tention of the public. A a 4 350 RETROGRADE ABSORBENTS. SECT, XXIX. i. DR. BEDDOES very ingenioufly concludes, from the florid colour of the blood of ccnfurnptive pati- ents, that it abounds in oxygene ; and that the rednefs of their tongues and lips, and the fine blufb of their cheeks fliew the prefence of the fame prin- ciple, like flefh reddened by nitre. And adds, that the eircumftance of the confumptions of preg- nant women being (lopped in their progrefs during ' pregnancy, at which time their blood may be fup- pofed to be in part deprived of its oxygene, by oxygenating the blood of the fcetus, is a forcible argument in favour of this theory ; which muft foon be confirmed or confuted by his experiments. See EiTay on Scurvy, Confumption, &c. by Dr. Beddoes. Murray. London. Alfo Letter to Dr, Darwin, by the fame. Murray. London, S E CT. SECT. XXiX. i. RETROGRADE ABSORBENTS- SECT. XXIX. ON THE RETROGRADE MOTIONS OF THE ABSORBENT SYSTEM. I. Account of the abforbent fyftem. II. The ial , . i i ' ' •,. II* The Valves of the Akforbent Syftem may fujfcr tbeir Fluids to regurgitate in fome Difeafes. i. THE many valves, which occur in the pro- grefs of the lymphatic and lacteal veflels, would feem infuperable o-bftacles to the regurgitation of their contents. But as thefe valves are placed in veflels, which are indued with life, and are them- felves indued with life alfq ; and are very irritable into thofe natural motions, which abforb, or propel the fluids they contain ; it is poflible, in fame dif- eafes, where thefe valves or veflels are ftimulated into unnatural exertions, or are become paralytic, that during the diaflole of the part of the yeflel to which the valve is attached, the valve may not fo completely clofe, as to prevent the relapfe of the lymph or chyle. This is rendered more probable, by the experiments of injecting mercury, or water, pr fuet, or by blowing air down thefe veflels : all which pafs the valves very eafily, contrary to the natural courfe of their fluids, when the veflels are, thus a little forcibly dilated, as mentioned by Dr. Haller, Elem. Phyfiol. t. iii. f. 4. " The valves of the thoracic duel: are few, fome afTert they are not more than twelve, and that they do not very accurately perform their office, as they do not clofe the whole area of the duel, and thencq may permit chyle to repafs them downwards. In living animals, however, though not always, yet morq SECT. XXIX. i. RETROGRADE ABSORBENTS. 355 more frequently than in the dead, they prevent the chyle from returning. The principal of thefe valves is that, which prelides over the infertion of the thoracic duel, into the fubclavian vein ; many have believed this alfo to perform the office of a valve, both to admit the chyle into the vein, and to pre- clude the blood from entering the duel; but in my opinion it is fcarcely fuffiqitnt for this purpofe." Haller, Elem. Phyf. t. vii. p. 226- 2. The mouths of the lymphatics feem to admit water to pals through them after death, the invert- ed way, eafier than the natural one ; fmce an in- verted bladder readily lets out the water with which it is filled; whence it may be inferred, that there is no obftacle at the mouths of thefe veflels to prevent the regurgitation of their contained fluids. I was induced to repeat this experiment, and having accurately tied the ureters and neck of a frefii ox's bladder, I made an opening at the fundus of it ; and then, having turned it infide outwards, filled it half full with water, and was furprifed to fee it empty itfelf fo haftily. I thought the experi- ment more appofite to my purpofe by fufpending the bladder with its neck downwards, as the lymphatics are chiefly fpread upon this part of it, as fhewn by Dr. Watibn, Philof. Tranf. v. 59. p. 392. 3. In fome difeafes, as in the diabetes and fcro- phula, it is probable the valves themfelves are dif- eaied, and are thence incapable of preventing the return of the fluids they mould fupport. Thus the valves of the aorta itfelf have frequently been found fchirrous, according to the difle&ions of Monf. Lieutaud, and have given rife to an inter- rupted pulfe, and laborious palpitations, by fuffer- ing a return of part of the blood into the heart. Nor are any parts of the body fo liable to fchirro- fity as the lymphatic glands and veflels, infomuch that 356 RETROGRADE ABSORBENTS. SECT. XXIX. 2. that their fchirroilties have acquired a diftind name, and been termed fcrophula. 4. There are valves in other parts of the body, analogous to thofe of the abforbent fyflem, and which are liable, when difeafed, to regurgitate their contents : thus the upper and lower orifices of the flomach are clofed by valves, which, when too great quantities of warm water have been drank with a defign to promote vomiting, have fometimes refift- ed the utmofl efforts of the abdominal mufcles, and diaphragm : yet, at other times, the upper valve, or cardia, eafily permits the evacuation of the con- tents of the flomach ; whilft the inferior valve, or pylorus, permits the bile, and other conten;s of the duodenum, to regurgitate into the flomach. 5. The valve of the colon is well adapted to pre- vent the retrograde motion of the excrements ; yet, as this valve is poiTefied of a living power, in the iliac paflion, either from fpafm, or other unnatural exertions, it keeps itfeif open, and either fuffers or promotes the retrograde movements of the contents of the inteftines below ; as in ruminating animals the mouth of the firft flomach feems to be fo con- flruded, as to facilitate or aflift the regurgitation of the food ; the rings of the cefophagus afterwards contracting themfelves in inverted order. De liaen, by means of a fyringe, forced fo much water into the redum inteflinum of a dog, that he vomited it in a full flream from his mouth ; and in the iliac paflion above mentioned, excrements and clyfler are often evacuated by the mouth. See Sedion XXV. 15. 6. The punda lacrymalia, with the lacrymai fack and nafal dud, compofe a complete gland, and much refemble the inteflinal canal : the punda lacrymalia are abforbent mouths, that take up the tears from the eye, when they have done their office there, and convey them, into the noftrils 5 but when the SECT. XXIX. 3. RETROGRADE ABSORBENTS. 357 the nafal duel is obftructed, and the lacrymal fac1* diftended with its fluid, on preflure with the finger the mouths of this gland (pun&a lacrymalia) will readily difgorge the fluid, they had previoufly abforbed, back into the eye. 7. As the capillary vefiels receive blood from the arteries, and feparating the mucus, or perfpirable matter from it, convey the remainder back by the veins ; thefe capillary veflels are a let of glands, in .every refpect fimilar to the fecretory veflels of the liver, or other large congeries of glands. The be- ginnings of thefe capillary veflels have frequent anaftomofes into each other, in which circumstance they are refembled by the lacteals ; and like the mouths or beginnings of other glands, they are a fet of abforbent veflels, which drii>k up the blood which is brought to them by the arteries, as the chyle is drunk up by the lacleals : for the circula- tion of the blood through the capillaries is proved to be independent of arterial impulfe ; fince in the blulh of fhame, and in partial inflammations, their aclion is increafed, without any increafe of the mo- tion of the heart. 8. Yet not only the mouths, or beginnings of thefe anaftomofing capillaries are frequently feen by microfcopes, to regurgitate fome particles of blood, during the ftruggles of the animal; but retrograde motion of the blood, in the veins of thofe animals, from the very heart of the extremity of the limbs, is obfervable, by intervals, during the dittrefles of the dying creature. Haller, Elem. Phyfioi. t. i. p. 216. Now, as the veins have perhaps all of them a valve fomewhere between their extremities and the heart, here is ocular demonflration of the fluids in this difeafed condition of the animal, re- pafling through venous valves : and it is hence highly probable, from the ftricteft analogy, that if the courfe of the fluids, in the lymphatic veflels, could RETROGRADE ABSORBENTS. SECT. XXIX. £ could be fubje&ed to microfcopic obfervation, they would alfo, in the difeafed ftate of the animal, be feen to repafs the valves, and the mouths of thofe vefTels, which had previoufly abforbed them, or promoted their progrefiion. IJI. Communication from the Alimentary Canal to the Bladder, by means of the Abforbent Veffels, MANY medical philofophers, both ancient and modern, have fufpecled that there was a nearer communication between the ftomach and the urinary bladder, than that of the circulation : they were led into this opinion from the great expedition with which cold water, when drank to excefs, pafTes off by the bladder ; and from the fimilarity of the urine, when produced in this hafty manner, with the material that was drank. The former of thefe circumftances happens per- petually to thofe who drink abundance of cold water, when they are much heated by exercife, ancj, to many at the beginning of intoxication. Of the latter, many inftaaces are recorded by Etmuller, t. xi. p. 716. where fimple water, wine, and wine with fugar, and emulfions, were returned by urine unchanged. , There are other experiments, that feem to de- monftrate the exigence of another paiTage to the bladder, befides that through the kidneys. Thus Dr. Kratzenftein put ligatures on the ureters of a dog, and then emptied the bladder by a catheter; yet in a little time the dog drank greedily, and made a quantity of water, (Difputat. Morbor. Halleri. t. iv. p. 63.) A fimiiar experiment is re- lated in the Philofophical Tranfaclions, with the fame event, (No. 65, 67, for the year J67O.) Add to this, that in fome morbid cafes the urine has continued to pafs, after the fuppiiration or total deftru&ion SECT. XXIX. 3. RETROGRADE ABSORBENTS. 359 deftru&ion of the kidneys ; of which many In- ftances are referred to in the Elem. Phyfiol. t. vii. p. 379. of Dr. Haller. From all which it muft be concluded, that fome fluids have pafled from the ftomach or abdomen, without having gone through the fanguiferous cir- culation : and as the bladder is fupplied with many lymphatics, as defcribed by Dr. Watfon, in the Philof. Tranf. v. 59. p. 392. and as no other veflels open into it befides thefe and the ureters, it feems evident, that the unnatural urine produced as above defcribed, when the ureters were tied, or the kid- neys obliterated, was carried into the bladder by the retrograde motions of the urinary branch of the lymphatic fyftem. The more certainly to afcertain the exiflence of another communication between the ftomach and bladder, befides that of the circulation, the follow- ing experiment was made, to which I muft beg your patient attention : — A friend of mine (June 14, 1772) on drinking repeatedly of cold fmali punch, till he began to be intoxicated, made a quantity of colourlefs urine. He then drank about two drams of nitre diflblved in fome of the punch, and eat about twenty ftalks of boiled afparagus : on continuing to drink more of the punch, the next urine that he made was quite clear, and without ftnell ; but in a little time another quantity was made, which was not quite fo colourlefs, and had a ftrong fmell of the afparagus : he then loft about four ounces of blood from the arm. The fmell of afparagus was not at all perceptible in the blood, neither when frem taken, nor the next morning, as myfelf and two others accurately attended to ; yet this fmell was ftrongly perceived in the urine, which was made juft before the blood was taken from his arm. Some 360 RETROGRADE ABSORBENTS. SECT. XXIX. 4, Some bibulous paper, moiftened in the ferum of this blood, and fuffered to dry, (hewed no figns of nitre by its manner of burning. But fome of the fame paper* moiftened in the urine, and dried, ori being ignited, evidently fliewcd the prefence of nitre. This blood and the urine flood fome days cxpofed to the fun in the open air, till they were evaporated to about a fourth of their original quan- tity, and be^an to (link : the paper which was then moiftened with the concentrated urine, mewed the prefence of much nitre by its manner of burning ; whilft that moiftened with the blood (hewed no fuch appearance at all. Hence it appears, that certain fluids at the begin- ning of intoxication, firid another paflage to the bladder befides the long courfe of the arterial cir- culation; and as the inteftinal abforbents are joined with the urinary lymphatics by frequent anaftomo- fes, as Hewfon has demonftfated ; and as there is no other road, we may juftly conclude, that thefe fluids pafs into the bladder by the urinary branch of the lymphatics, which has its motions inverted during the difeafed ftate of the animal. A gentleman, who had been fome weeks affected with jaundice, arid whofe Urine was in cohfequence of a very deep yellow^ took fome cold fmall punch, in which was dilfolved about a dram of nitre ; he then took repeated draughts of the punch, and kept himfelf in a cool room, till on the approach of flight intoxication he made a large quantity of water ; this water had a flight yellow tinge, as might be expected from a fmall admixture of bile fecreted from the kidneys 5 but if the whole of it had pafled through the languiferous veflels, which were now replete with bile (his whole (kin being as yelfow as gold) would not this urine alfo, as well as that he had made for weeks before, have been of a deep yellow ? Paper dipped in this watef, ahdi dryedj SECT. XXIX. 4. RETROGRADE ABSORBENTS. 361 dryed, and ignited, (hewed evident marks of the prefence of nitre, when the flame was blown out. IV. Tie Phenomena of the Diabetes explained, and of fome Diarrhoeas. THE phenomena of many difeafes are only ex- plicable from the retrograde motions of fome of the branches of the lymphatic fyftem ; as the great and immediate flow of pale urine in the beginning of drunkennefs ; in hyfteric paroxyfms ; from being expofed to cold air ; or to the influence of fear or anxiety. Before we endeavour to illuftrate this doctrine, by defcribing the phenomena of thefe difeafes, we muft premife one circumftance ; that all the branches of the lymphatic fyftem have a certain fympathy with each other, infomuch that when one branch is ftimulated into unufual kinds or quan- tities of motion, fome other branch has its motions either increafed, or decreafed, or inverted at the fame time. This kind of fympathy can only be proved by the concurrent teftimony of numerous facts, which will be related in the courfe of the work. 1 (hall only add here, that it is probable, that this fympathy does not depend on any commu- nication of nervous filaments, but on habit ; owing to the various branches of this fyftem having fre- quently been ftimulated into action at the fame time. There are a thoufand inftances of involuntary motions aflbciated in this manner ; as in the a& of vomiting, while the motions of the ftomach and cefophagus are inverted, the pulfations of the arte- rial fyftem by a certain fympathy become weaker ; and when the bowels or kidneys are ftimulated by poifon, a ftone, or inflamation, into more violent adion ; the ftomach and cefophagus by fympathy in- vert their motions. I. When 362 RETROGRADE ABSORBENTS. SECT. XXIX. £ 1. When any one drinks a moderate quantity of vinous fpirit, the whole fyftem acts with more energy by confent with the ftomach and inteftines, as is feen from the glow on the fkin, and the increafe of ftrength and activity ; but when a greater quan» tity of this inebriating material is drank, at the fame time that the lafteals are excited into greater action to abforb it ; it frequently happens, that the urinary branch of abforbents, which is connected with the lacteals by many anaftomofes, inverts its motions, and a great quantity of pale unanimalized urine is difcharged* By this wife contrivance too much of an unneceffary fluid is prevented from entering the circulation—This may be called the drunken diabetes, to diftinguilh it from the other temporary diabetes, which occur in hyfteric difea- fes, and from continued fear or anxiety. 2. If this idle ingurgitation of too much vinous fpirit be daily practifed, the urinary branch of ab- forbents at length gains an habit of inverting its motions, whenever the la&eals are much ftimula- ted ; and the whole or a great part of the chyle is thus daily carried to the bladder without entering the circulation, and the body becomes emaciated. This is one kind of chronic diabetes^ and may be diflinguifhed from the others by the tafte and ap- pearance of the urine; which is fweet, and the colour of whey, and may be termed the chylife- tous diabetes. 3 Many children have a fimilar difpofition of chyle in their urine, from the irritation of worms in their inteftines, which ftimulating the mouths of the lafteals into unnatural a&ion, the urinary branch of the abforbents becomes inverted, and carries part of the chyle to the bladder ; part of the chyle alfo has been carried to the iliac and lumber 'glands, of which inftances are recorded by Haller, t. vii. 2 25. and which can be explained on no other theory ; XXIX 4. RETROGRADE ABSORBENTS. 363 theory : hut the directions of the lymphatic fyftem of the human body, v/hich have yet been publifh- ed, are not fufficiently extenfive for our purpofe ; Jet if we may reafon from comparative anatomy, this tranflation of chyle to the bladder is much illuftrated by the account given of this fyflem of vefiels in a -turtle, by Mr. Hewfon, who obferved, " That the la&eals near the root of the mefentery anaftomofe, fo as to form a net-work, from which feveral large branches go into fome confiderable lymphatics lying near the fpine ; and which can be traced almoft to the anus, and particularly to the kidneys. Philof. Tranf. v. 59. p. 199 — Enquiries, p. 74. 4. At the fame time that the urinary branch of abforbents, in the beginning of diabetes, is excited into inverted action, the cellular branch is excited by the fympathy above mentioned, into more ener- getic action ; and the fat, that was before depofited, is reabforbed and thrown into the blood vefiels ; \vhere it floats, and was miftaken for chyle, till the late experiments of the ingenious Mr. Hewfon de- monflrated it to be fat. This appearance of what was miftaken for chyle in the blood, which was drawn from thefe patients, and the obftructed liver, which very frequently accompanies this difeafe, feems to have led Dr. Mead to fulpect the diabetes was owing to a defect of fanguifkation ; and that the fchirrofity of the liver was the original caufe of it; but as the fchir- rhus of the liver is moft frequently owing to the fame caufes, that produce the diabetes and dropfies; namely, the great ufe of fermented liquors ; there is no wonder they mould exift, together, without being the confequence of each other. 5. If the cutaneous branch of abforbents gains a habit of being excited into ftronger action, and imbibes greater quantities of moifture from the VOL. I. B b atmofphere, 364 RET AGGRADE ABSORBENTS. SECT. XXIX- 4 atmofpbere, at the fame time that the urinary branch has its motions inverted, another kind of diabetes is formed, which may be termed the aque- ous diabetes. In this diabetes the cutaneous abfor- bents frequently imbibe an amazing quantity of atmofpheric moifture, infomuch that there are au- thentic hiftories, where many gallons a day, for many weeks together, above the quaritity that has been drank, have been difcharged by urine. Dr. Keil, in his Medicina Statica, found that he gained eighteen ounces from the moid air of one night ; and Dr. Percival affirms, that one of his hands imbibed, after being well chafed, near an ounce and half of water, in a quarter of an hour. (Tranfaft. of the College, London, vol. ii. p. 102.) Home's Medic. Fads, p. 2. feel. 3. The pale urine in hyfterical women,, or which is produced by fear or anxiety, is a temporary com- plaint of this kind ; and it would in reality be the fame difeafe, if it was confirmed by habit, 6. The purging (loots, and pale urine, occafion- ed by expofing the naked body to cold air, or fprinkling it with cold water, originate from a fimi- tar caufe \ for the mouths of the cutaneous lympha- tics being fuddenly expofed to cold become torpid, ^and ceafe, or nearly ceafe, to ad; whilft, by the fympathy above d.efcribed, not only the lymphatics of the bladder and inteftines ceafe alfo to abforb the more aqueous and faline part of the fluids fecre- ted into them ; but it is probable that theie lym- phatics invert their motions, and return* the fluids, which were previouily abforbed, into the inteftines and bladder. At the very inflant that the body is expofed naked to the cold air, an unufual movement is felt in the bowels ; as is experienced by boya going into the cold bath : this could not occur from . an obftru&ion of the perfpirable matter, fince there is 5tCT.XXiX.4. RETROGRADE ABSORBENTS, 365 is not time for that to be returned to the bowels by the courfe of the circulation. There is alfo a chronic aqueous diarrhoea, in which the atmofpheric moifture, drank up by the cutaneous and pulmonary lymphatics, is poured into the inteftines, by the retrograde motions of the lacteals. This difeafe is mod fimilar to the aqueous diabetes, and is frequently exchanged for it : a diftinft inflance of this is recorded by Ben- ningerus, Cent. v. Obf. 98. in which an aqueous diarrhoea fucceeded an aqueous diabetes, and de- ftroyed the patient* There is a curious example of this, described by Sympfon fDe Re Medica) — " A young man (fays he) was feiz'ed with a fever, upon, which a diarrhoea came on, with great ftupor; and he refufed to drink any thing, though he was parch- ed up with exceflive heat : the better to fupply him with moifture, I directed his feet to be immerfed in cold water ; immediately I obferved a wonderful decreafe of water in the veflel, and then an impe- tuous ftream of a fluid, fcarcely coloured, was dif- charged by ftool, like a cataract. " 7. There is another kind of diarrhoea, which has been called cseliaca ; in this difeafe the chyle, drank up by the lacleals of the fmall inteftines, is proba- bly poured into the large inteftines, by the retro- grade motions of their lacleals : as in the chylife- rous diabetes, the chyle is poured into the bladder, by the retrograde motions of the urinary branch of abforbents. The chyliferous diabetes, like this chyliferous diarrhoea, produces fudden atrophy ; fmce the nou- ri&ment, which ought to fupply the hourly wafte of the body, is expelled by the bladder, or reclum : whilft the aqueous diabetes, and the aqueous diarr- hoea produce exceflive thirft ; becaufe the. moifture, which is obtained from the atmofphere, is not con- veyed to the thoracic receptacle, as it ought to be, B b 2 but RETROGRADE ABSORBENTS. SECT. XXlX 4 but to the bladder, or lower inteflines ; whence the chyle, blood, and whole fyftem of glands, are rob- bed of their proportion of humidity. 8. There is a third fpecies of diabetes, in which the urine is mucilaginous, and appears ropy in pouring it from one veflel into another ; and will fometimes coagulate over the fire. This difeafe appears by intervals, and ceafes again, and feems to be occafioned by a previous dropfy in fome part of the body. When fuch a collection is reabforbed, it is not always returned into the circulation ; but the fame irritation that Stimulates one lymphatic branch to reabforb the depofited fluid, inverts the urinary branch, and pours it into the bladder, Hence this mucilaginous diabetes is a cure, or the confequence of a cure, of a worfe difeafe, rather than a difeafe itfelf. Dr. Cotunnius gave half an ounce of cream of tartar, every morning, to a patient, who had the anafarca ; and he voided a great quantity of urine ; a part of which, put over the fire, coagulated, on the evaporation of half of it, fo as to look like the jarhite of an egg. De Ifchiade Nervos. This kind of diabetes frequently precedes a dropfy ; and has this remarkable circumilance at- tending it, that it generally happens in the nighty as during the recumbent ftate of the body, the fluid, that was accumulated in the cellular membrane., or in the lungs, is more readily abforbed, as it is lefs impeded by its gravity. I have feen more than one inftance of this difeafe. Mr. D. a man in the decline of life, who had long accuftomed himfelf to fpirituous liquor, had fwelled legs, and other fymptoms of approaching anafarca j about once in a week, or ten days, for feveral months, he was feized, on going to bed, with great general uneafi- nefs, which his attendants refembled to an hyfteric fit $ and which terminated jp a great difeharge of vifcid S*CT. XXIX. 4. RETROGRADE ABSORBENTS. 367 vifcid urine ; his legs became lefs fwelled, and he continued in better health for fome days afterwards, I had not the opportunity to try if this urine would coagulate over the fire, when part of it was evapo- rated, which I imagine would be the criterion of this kind of diabetes ; as the mucilaginous fluid de- pofited in the cells and cyfts of the body, which have no communication with the external air, feems to acquire, by ftagnation, this property of coagula- tion by heat, whieh the fecreted mucus of the in- teftines and bladder do not appear to potTefs ; as I have found by experiment; and if any one fhould fuppofe this coagulable urine was feparated from the blood by the kidneys, he may recollect that in the moft inflammatory difeafes, in which the blood is niofl replete or moft ready to part with the coagu- lable lymph, none of this appears in the urine. 9. Different kinds of diabetes require different methods of cure. For the firft kind, or chylife- rous diabetes, alter clearing the ftomach and in- tedines, by ipecacuanha and rhubarb, to evacuate any acid material, which may too powerfully ftimu- late the mouths of the lacteals, repeated and large dofes of tincture of cantharides have been much re- commended. The fpeciftc flimulus of this medi- cine, on the neck of the bladder, is likely to excite the numerous abforbent veflels, which are fpread on that part, into ftronger natural actions, and by that means prevent their retrograde ones ; till, by per- fifting in the ufe of the medicine, their natural habits of motions might again be eftablifhed, Another indication of cure, requires fuch medicines, as by lining the inteflines with mucilaginous fub- ftances, or with iuch as confifl of fmooth particles, or which chemically deftroy the acrimony of their contents, may prevent the too great action of the inteftinal abiorbents. For this purpofe, I have found the earth precipitated from afolution of alum, by 36$ RETROGRADE ABSORBENTS. SECT. XXIX. 4, by means of fixed alcali, given in the dofe of half a dram every fix hours, of great advantage, with a few grains of rhubarb, fo as to produce a daily eva^ cuation. The food fhould confift of materials that have the leaft ftimulus, with calcareous water, as of Briflol and Matlock; that the mouths of the laOeals may be as little ftimulated as is neceffary for their proper abforption ; left with their greater exertions, fhould be connected by fympathy, the inverted motions of the urinary lymphatics. The fame method may be employed with equal advantage in the aqueous diabetes, fo great is the fympathy between the (kin and the ftomach. To which, however, fome application to the fkin might be ufefully added ; as rubbing the patient all over with oil, to prevent the too great adion of the cuta* neous abforbents. I knew an experiment of this kind made upon one patient with apparent adyan? tage. The mucilaginous diabetes will require the fame treatment, which is mod efficacious in the dropfy, and will be defcribed below. I mud add, that the diet and medicines above mentioned, are ftrongly recommended by various authors, as by Morgan, Willis, Harris, and Etmuller; but more hiftories of the fuccefsful treatment of thefe difeafes are •wanting to fully afcertain the moil efficacious me- thods of cure. In a letter from Mr. Charles Darwin, dated April 24, 1778, Edinburgh, is the fubfequent paiTage: — • " A man who had long laboured under a diabetes died yefterday in the clinical ward. He had for fome time drank four, and pafled twelve pounds of fluid daily ; each pound of urine contained an ounce of lugar. He took, without confiderable relief, gum kino, fanguis draconis melted with alum, tinc- ture of cantharides, ifinglafs, gum arabic, crabs. SECT. XXIX. 4. RETROGRADE ABSORBENTS. 369 eyes, fpirit of hartfhorn, and eat ten or fifteen cyders thrice a day. Dr. Home, having read my thefis, bled him, and found that neither the frefh blood nor the ferum tafted fweet. His body was opened this morning — every vifcus appeared in a found and natural ftate, except that the left kidney had a very fmall pelvis, and that there was a con- fiderable enlargement of moft of the mefenteric lym- phatic glands. I intend to infert this in my thefis, a£ it coincides with the experiment, where fome afparagus was eaten at the beginning of intoxica- tion, and its fmell perceived in the urine, though not in the blood. ' The following cafe of chyliferous diabetes is ex- tracted from fome letters of Mr. Hughes, to whofe unremitted care the infirmary at Stafford for many years was much indebted. Dated October 10, 1778- Richard Davis, aged 33, a whitefmith by trade, had drank hard by intervals ; was much tro'ubled with fwead-ng of his hands, which incommoded him in his occupation, but which ceafed on his fre- quently dipping them in lime. About feven months ago he began to make large quantities of water ; his legs are cedematous, his belly tenfe, and he complains of a rifing in his throat, like the globus hyftericus : he eats twice as much as other people, drinks about fourteen pints of fmall beer a day, befides a pint of ale, fome milk-porridge, and 3. baion of broth, and he makes about eighteen pint§ of water a-day. He tried alum, dragon's .blood, flee!, blue vitriol, and cantharides in large quantities, and duly re- peated, under the care of Dr. Underbill, but with- out any effect ; except that on the day after he omitted the cantharides, he made but twelve pints of water, but on the next day this good effect ceafed 37° RETROGRADE ABSORBENTS. SECT. XXIX. 4, November 21. — He made eighteen pinrs of water, and he now, at Dr. Darwin's requeft, took a grain of opium every four hours, and five grains of aloes at night ; and had a flannel fhirt given him. 22. — Made fixteen pints. 23, — Thirteen pints : drinks lefs, 24. — Increafed the opium to a grain and quarter every four hours : he made twelve pints. 25." — Increufed the opium to a grain and half : he now makes ten pints j and drinks eight pints in a day. The opium was gradually increafed during the next fortn'ght, till he took three grains every four hours, but without any further diminution of his water. During the ufe of the opium he fweat much in the nights, fo as to have large drops ftand on his face and all over him, The quantity of opium was then gradually decreafed, but not totally omit- ted, as he continued to take aboiit a grain morning and evening. January 17. — He makes fourteen pints of water a day. Dr. Underhill now directed him two fcruples of common rofm triturated with as much fugar, every fix hours ; and three grains of opium every night. 19.— Makes fifteen pints of water: fweats at night. 21. — Makes feyenteen pints of water ; has twitch- ings of his limbs in a morning, and pains of his legs : he now takes a dram of rofm for a dofe, and continues the opium. 23. — Water more coloured, and reduced to fix- teen pints, and he thinks has a brackifh tafle. 26. -Water reduced to fourteen pints. 28. — -Water thirteen pints ; he continues the opium, and takes four fcruples of the rofm for a dofe. February i. — Water twelve pints. 4CrWatcr SECT. XXIX. 4. RETROGRADE ABSORBENTS. 371 4.— Water eleven pints : twitchings lefs ; takes five fcrupl'is for a dole. 8.— Water ten pints: has had many (tools, 12. — Appetite lefs : purges very much. After this the roiin either purged him, or would not ftay on his ftomat h ; and he gradually relapfed nearly to his former condition, and in a few months funk under the difeafe. October 3, Mr. Hughes evaporated two quarts of the water, and obtained from it four ounces and half of a hard and brittle faccharine rnafs, like trea- cle which had been fome time boiled. Four ounces of blood, which he took from his arm with defign. to examine it, had the common appearances, ex- cept that the ferum refembled cheeie-whey ; and that on the evidence of four perfons, two of whom did not know what it was they tailed, the ferum had aj'iltijh t-ifte. From hence it appears, that the faccharine matter, with which the urine of thefe patients fo much abounds, does not enter the blood-veflels like the nitre and afparagus mentioned above ; but that the proceis of digeftion relembles the procefs of the germination of vegetables, or of making barley into malt; as the vait quantity of fugar found in the jurine mud be made from the food which he took (which was double that taken by others), and from the fourteen pints of fmall beer which he drank. And, fecondly, as the ferum of the blood was not fweet, the chyle appears to have been conveyed to the bladder without entering the circulation of the blood, lince fo large a quantity of fugar, as was found in the urine, namely, twenty ounces a day, could not have previoufly exifted in the blood with- out being perceptible to the tafte. November i. Mr. Hughes diflblved two drams of nitre in a pint of a decoction of the roots of afparagus, and added to it two ounces of tincture of 57* RETROGRADE ABSORBENTS. SECT. XXIX. 4. I of rhubarb : the patient took a fourth part of this mixture every five minutes, till he had taken the whole. — In about half an hour he made eighteen ounces of water, which was very manifeftly tinged with the rhubarb j the fmell of the afparagus was doubtful. He then loft four ounces of blood, the ferum of which was not fo opake as that drawn before, but of a yellowim caft, as the ferum of the blood ufually appears. Paper, dipped three or four times in the tinged urine and dried again, did not fcintillate when it was fet on fire; but tfhen the flame was blown out, the fire ran along the paper for half an inch ; which, when the fame paper was unimpregnated, it would not do ; nor when the fame paper was dipped in urine made before he took the nitre, and dried in the fame manner. Paper, dipped in the ferum of the blood and dried in the lame manner as in the urine, did not fcintillate when the flame was blown out, but burnt exactly in the fame manner as the fame paper dip- ped in the ferum of blood drawn from another per* fon. This experiment, which is copied from a letter of Mr. Hughes, as well as the former, feems to evince the exiftence of another paflage from the inteftines to the bladder, in this difeafe, befides that of the fanguiferous fyftem ; and coincides with the curious experiment related in fedlion the third, except that the fmell of the afparagus was not here perceived, owing perhaps to the roots having been made ufe of inftead of the heads. The rifing in the throat of this patient, and the twhchings of his limbs, feem to indicate fome fimi- larity between the diabetes and the hyfteric difeafe, befides the great flow of 'pale urine, which is com- mon to them both. Perhaps SECT. XXIX. 5. RETROGRADE ABSORBENTS. 375 Perhaps if the mefenteric glands were nicely in* fpefted in the diffeftions of thefe patients ; and if the thoracic duel, and the larger branches of the lacteals, and if the lymphatics, which arile from the bladder, were well examined by injection, or by the knife, the caufe of diabetes might be more ceiv tainly underllood. 'I lie opium alone, and the opium with the rofm, feem much to have ferved this patient, and might probably have effected a cure, if the difeafe had been (lighter, or the medicine had been exhibited, before it had been confirmed by habit during the feven months it had continued. The increafe of the quantity of water on beginning the large dofes of rofm was probably owing to his, omitting the jnorning dofes of opium. V. The Phenomena of Dropjtes explained,. I. SOME inebriates have their paroxyfms of in- ebriety terminated by much pale urine, or profufe fweats, or vomiting, or (tools ; others have their . paroxyfms terminated by ftupor, or fleep, without the above evacuations. The former kind of thefe inebriates have been obferved to be more liable to diabetes and dropfy ; and the latter to gout, gravel, and leprofy. Evoe ! attend ye bacchanalians ! dart at this dark train of evils, and, amid yqar immodeft jefts, and idiot laughter, recoiled, Quern Deus volt perdere, prius dementat. In thofe who are fubjecl: to diabetes and dropfy, the abforbent veflels are naturally more irritable in the latter j and by being frequently diilurb- ed 374 RETROGRADE ABSORBENTS. SECT. XXIX. s. ed or inverted by violent ftimulus, and by their too great fympathy with each other, they become at length either entirely paralytic, or are only fufcep- tible of motion from the ftimulus of very acrid materials ; as every part of the body, after having been ufed to great irritations, becomes lefs affe&ed by fmaller ones. Thus we cannot diftinguim ob- je&s in the night, for fome time after we come out of a ftrong light, though the iris is prefently dila- ted; and the air of a fummer evening appears cold, after we have been expofed to the heat of the day. There are no cells in the body, where drqpfy may not be produced, if the lymphatics ceafe to abforb that mucila /inous fluid, which is perpetually de- pofited in them, for the purpofe of lubricating their furfaces. If the lymphatic branch, which opens into the cellular membrane, either does its office imperfect- ly, or not at all ; thefe cells become replete with a mucilaginous fluid, which, after it has ftagnated fome time in the cells, will coagulate over the fire ; and is erroneoufly called water. Wherever the feat of this difeafe is, (uniefs in the lungs or other pendent vifcera) the mucilaginous liquid above mentioned will fubfide to the mod depending parts of the body, as the feet and legs, when thofe are lower than the head and trunk ; for all thefe qells have communications with each other. When the cellular abforbents are become infen- ble to their ufual irritations, it mod frequently hap- pens, but not always, that the cutaneous branch of abforbents, which is ftridtly afibciated with them, fuffers the like inability. And then, as no water is abforbed from the atmofphere, the urine is not only lefs diluted at the time of its fecretion, and confequently in lefs quantity and higher coloured : but SICT. XXIX. 5. RETROGRADE ABSORBENTS. but great third is at the fame time induced, for as no water is abforbed from the atmofphere to dilute the chyle and blood, the la&eals and other abfor- bent vefiels, which have not loft their powers, are excited into more conftant or more violent action, to fupply this deficiency ; whence the urine be- comes dill lefs in quantity, and of a deeper colour, and turbid like the yolk of an egg, owing to a greater abforption of its thinner parts. From this ftronger action of thofe abforbents, which fiill re- tain their irritability, the fat is alfo abforbed, and the whole body becomes emaciated. This increafed exertion of fome branches of the lymphatics, while others are totally or partially paralytic, is refembled by what conftantly occurs in the hemiplagia ; when the patient has loft the ufe of the limbs on one fide, he is incefiantly moving thofe of the other ; for the moving power, not having accefs to the paralytic limbs, becomes redundant in thofe which are not difeafed. The paucity of urine and thirft cannot be ex- plained from a greater quantity of mucilaginous fluid being depofited in the cellular membrane : for though thefe fymptoms have continued many weeks, or even months, this collection frequently does not amount to more than very few pints. Hence alfo the difficulty of promoting copious fweats in anafarca is accounted for, as well as the great thirft, paucity of urine, and lofs of fat ; (ince, when the cutane- ous branch of abforbents is paralytic, or nearly fo, there is already too fmall a quantity of aqueous fluid in the blood : nor can thefe torpid cutaneous lymphatics be readily excited into retrograde mo- tions. Hence likewife we under ftand, why in the af- cites, and fome other dropfies, there is often no thirft, and no paucity of urine ; in thefe cafes the RETROGRADE ABSORBENTS. ^ECT. XX1&. f. the cutaneous abforbents continue to do their office. Some have believed, that dropfies were occafion- ed by the inability of the kidneys, from having only obferved the paucity of urine ; and have theflce laboured much to obtain diuretic medicines ; but it is daily obfervable, that thofe who die of a total inability to make water, do not become dropficai in confequence of it : Fernelius mentions one, who laboured under a perfect fuppreflion of urine during twenty days before his death, and yet had no fyrop- toms of dropfy. Pathol. 1. vi. c. 8. From the fame idea many pbyficians have retrained their pa- tients from drinking, though their thirft has been very urgent ; and fome cafes have been publifhed, where this cruel regimen has been thought advan- tageous : but others of nicer obfervation are of opinion, that it has always aggravated the diftrefies of the patient ; and though it has abated his fwell- ings, yet by inducing a fever it has haftened his difiblution. See Tranfaclions of the College, Lon- don, vol. ii. p. 235. Cafes of Dropfy by Dr. G< Baker. The cure of anafarca, fo far as refpecls the eva- cuation of the accumulated fluid, coincides with the idea of the retrograde action of the lymphatic fyftem. It is well known that vomits, and other drugs, which induce ficknefs or naufea ; at the fame time that they evacuate the ftomach, produce a great abforption of the lymph accumulated in the cellular membrane. In the operation of a vomit, not only the motions of the ftomach and duodenum become inverted, but alfo thofe of the lymphatics and lafteals, which belong to them ; whence a great quantity of chyle and lymph is perpetually poured into the ftomach and inteftines, during the opera- tion, and evacuated by the mouth. Now at the fame SECT. XXIX. 5. RETROGRADE ABSORBENTS. 377 fame time, other branches of the lymphatic fyftem, viz. thofe which open on the cellular membrane, are brought into more energetic action, by the fympathy above mentioned, and an increafe of their abforption is produced. Hence repeated vomits, and cupreous falts, and fmall dofes of fquill or foxglove, are fo efficacious in this difeafe. And as draftic purges aft alfo by inverting the motions of the la&eals ; and thence the other branches of lymphatics are induced into more powerful natural action, by fympathy, and drink up the fluids from all the cells of the body ; and by their anaftomofes, pour them into the lac- teal branches ; which, by their inverted actions, return them into the inteftines ; and they are thus evacuated from the body : — thefe purges alfo are ufed with fuccefs in discharging the accumulated, fluid in anafarca. II. The following cafes are related with defign to afcertain the particular kinds of dropfy in which the digitalis purpurea, or common foxglove, is preferable to fquill, or other evacuants, and wrere firft publifhed in 1780, in a pamphlet entitled Ex- periments on mucilaginous and purulent Matter, &c. Cadell. London. Other cafes of dropfy, treat- ed with digitalis^ were afterwards publimed by Dr. Darwin in the Medical Tranfadions, vol. iii. in which there is a miflake in refpect to the dofe of the powder of foxglove, which mould have been from five grains to one, inftead of from five grains to ' ten. Anafarca of the Lungs. i. A lady, between forty and fifty years of age, had been indifpofed fome time, was then feized with cough and fever, and afterwards expectorated much •Jfrfc RETROGRADE ABSORBENTS. SECT. XXIX. 5, much digefted mucus. This expectoration fud- • denly ceafed, and a confiderable difficulty of brea- thing fupervened, with a pulfe very irregular both in velocity and flrength ; (he was much diftrefled at firft lying down, and at firft rifing ; but after a minute or two bore either of thofe attitudes with eafe. She had no pain or numbnefs in her arms 5 fhe had no hectic fever, nor any cold fhiverings, and the urine was in due quantity, and of the na- tural colour. The difficulty of breathing was twice confidera- bly relieved by fmall dofes of ipecacuanha, which operated upwards and downwards, but recurred in a few days : (he was then directed a decoction of foxglovej (digitalis purpurea) prepared by boiling four ounces of the freih leaves from two pints of water to one pint ; to which was added two ounces of vinous fpirit : me took three large fpoonfuls of this mixture every two hours, till me had taken it four times; a, continued ficknefs fupervened, with frequent vomiting, and a copious flow of urine : thele evacuations continued at intervals for two or three days, and relieved the difficulty of breathing — She had fome relapfes afterwards, which were again relieved by the repetition of the decoclian of foxglove. 2. A gentleman, about fixty years of age, who had been addicted to an immoderate ufe of fer* mented liquors, and had been very corpulent, gra- dually loft his ftrength and fleflh, had great diffi- culty of breathing, with legs forriewhat fwelled; and a very irregular pulfe. He was very much diftrefied at firft lying down, and at firft rifing from his bed, yet in a minute or two was eafy in both thofe attitudes- He made ftraw-coloured urine in due quantity, and had no pain or numbnefs of his arms. He Jfkcr.XXlX;$. RETROGRADE ABSORBENTS. 379 He took a large fpoonful of the decodion of fox- glove, as above, every hour, for ten or twelve fuc- ceflive hours, had inceflant ficknefs for about two days, and pafTed a large quantity of urine, upon which his breath became quite eafy, and the fwell- ihg of his legs fubfided ; but as his whole confti- tution was already finking from the previous intem- perance of his life, he did not furyive more than three or four months. Hydrops Pericardii. 3. A gentleman of temperate life and fedulou^ application to bufmefs, between thirty and forty years of age, had long been fubjecl, at intervals, to an irregular pulfe : a few months ago he became vveak, with difficulty of breathing, and dry cough. In this fituation a phyfician of eminence directed him to abflain from all animal food arid fermented liquor, during which regimen all his complaints increaTed ; he now became emaciated, and totally loft his appetite ; his pulfe Very irregular both in velocity and ftrength; with great difficulty of breath- ing, and fo me f welling of his legs; yet he could lie down horizontally in his bed, though he got little fleep, and paflfed a due quantity of urine, and of the natural colour: no fullnefs or hardnefs could be perceived about the region of the liver ; and he had no pain or numbnefs in his arms. One night he had a moft profufe fweat all ovec his body and lim'bs, which quite deluged his bed, and for a day or two fomewhat relieved his diffi- culty of breathing, and his puife became lefs irre- gular : this copious fweat recurred three or four times at the intervals of five or fix days,, and re- peatedly alleviated his fymptonis. C G He 380 RETROGRADE ABSORBENTS. SECT. XXIX. $. He was direded one large fpoonful of the above decoction of fox-glove every hour, till it procured fome considerable evacuation : after he had taken it eleven fucceffive hours he had a few liquid ftools, attended with a great flow of urine, which lad had a dark tinge, as if mixed with a few drops of blood : he continued fick at intervals for two days, but his breath became quite eafy, and his pulfe quite regular, the fwelling of his legs difappcared, and his appetite and fleep returned. He then took thiee grains of white vitriol twice a day, with fome bitter medicines, and a grain of opium with five grains of rhubarb every night ; was advifed to eat fiefh meat, and fpice, as his {lomach would bear it, with fmall beer, and a few glafles of wine ; and had iiTues made in his thighs , and has fuffered no relapfe^ 4. A lady, about fifty years of age, had for fome weeks great difficulty of breathing, with very irre- gular pulfe, and confiderable general debility : fhe could lie down in bed, and the urine was in due quantity and of the natural colour, and fhe had no pain or numbnefs of her arms. She took one large fpoonful of the above decoc- tion of foxglove every hour, for tenor twelve fuc- ceflive hours ; was lick, and made a quantity of pale urine for about two days, and was quite re- lieved both of the difficulty of breathing, and the irregularity of 'her pulfe. She then took a grain of opium, and five grains of rhubarb, every night, fqr many weeks ; with fome flight chalybeate and bitter medicines, and has fuffered no relapfe. Hydrops TTiorads. 5. A tradefman, about fifty years of age, became weak- and Ihort of breath, efpecially on increafe of motion* SECT. XXIX. 5. RETROGRADE ABSORBENTS, 381 motion, with pain in one arm, about the infertion of the biceps mufcle. He obferved he fometimes in the night made an unufual quantity of pale \vater. He took calomel, alum, andperuvian bark, and all his fymptoms increafed: his legs began ta fwell confiderably ; his breath became more diffi- cult, and he could not lie down in bed ; but all this time he made a due quantity of ilraw-coloured water. The decoclion of foxglove was given as in the preceding cafes, which operated chiefly by purging, and feemed to relieve his breath for a day or two ; but alfo feemed to contribute to weaken him. — He became after fome weeks univerfally dropfical, and died comatous. 6. A young lady of delicate conftitution, with' light eyes and hair, and who had perhaps lived too' abflemioufly both in refpe6t to the quantity and quality of what Che eat and drank, was feized with great difficulty of breathing, fo as to threaten im- mediate death. Her extremities were quite cold, and her breath felt cold to the back of one's hand. She had no fweat, nor could lie down for a iingle' moment ; and had previoufly, and at prefent, com- plained of great weaknefs and pain and numbnefs' of both her arms ; had no fwelling of her legs, no third, water in due quantity and colour. Her fifter, about a year before, was afflidted with fimilar fymp- toms, was repeatedly blooded, and died univerfally dropfical. A grain of opium was given immediately, and repeated every fix hours with evident and amazing advantage ; afterwards a blifter, with chalybeates, bitters, and eifenrial oils, were exhibited, but no- thing had fuch eminent effecT: in relieving the difficulty of breathing and coldnefs of her extremi- ties as opium, by the ufe of which in a few weeks Cc 2 file 5Sa RETROGRADE ABSORBENTS. SECT. XXIX. £ fhe perfectly regained her health, and has fuffered uo relapfe. Af cites. 7. A young lady of delicate conftitution having been expofed to great fear, cold, and fatigue, by the overturn of a chaife in the night, began with pain and tumour in the right hypochondrium : in a few months a flucluation was felt throughout the whole abdomen, more diftinclly perceptible indeed about the region of the ftomach ; fince the inte- guments of the lower part of the abdomen gene- rally become thickened in this difeafe by a degree of anafarca. Her legs were not fw'elled, no third, water in due quantity and colour. — She took the foxglove fo as to induce ficknefs and ftools, but without abating the fwelling, and was obliged at length to fubmit to the opeiation of tapping. 8. A man about fixty-feven, who had long been accuftomed to fpirituous potation, had fome time laboured under afcites ; his legs fomewhat fwelled ; his breath eafy in all attitudes \ no appetite ; great third ; urine in exceedingly fmall quantity, very deep coloured, and turbid ; pulfe equal. He took the foxglove in fuch quantity as vomited him, and induced ficknefs for two days ^ but procured no flow of uiine, of diminution of his fwelling ; but \vas thought to leave him confiderably weaker. 9. A corpulent man, accuftomed to large potati- on of fermented liquors, had vehement cough, dif- ficult bieathing, anafarca of his legs, thighs, and hands, and confiderabte tumour, with evident flue- tuation of his abdomen ; his pulfe was equal ; his urine in fmall quantity, of deep colour, and turbid. Thefe fwellings had been twice confiderably abated by drailic cathartics. He took three ounces of a of foxglove (made by boiling one ounce of SECT. XXIX. 5. RETROGRADE ABSORBENTS. 383 of the frefh leaves in a pint of water) every three hours, for twq whole days ; it then began to vomit arjd purge him violently, and promoted a great flow of urine ; he was by thefe evacuations completely emptied in twelve hours. After two or three months all thefe fymp\o;us returned, and were again re- lieved by the ufe of the foxglove ; and thus in the ipace of about three years he was about ten times evacuated, and continued all that time his ufual potations: excepting at fir ft, the medicine operated only by urine, and did not appear confiderably to weaken him. — The laft time he took it, it had no effect ; and a few weeks afterwards he vomited a great quantity of blood, and expired. QJEJERIES. 1. As the firft fix of thefe patients had a due difcharge of urine, and of the natural colour, was ijot the feat of the difeafe confined to fome part of the thorax, and the fwelling of the legs rather a fymptom of the obftrucled circulation of the blood, than of a paralyi'is of the cellular lymphatics of thofe parts ? 2. When the original difeafe is a general ana- farca, do not the cutaneous lymphatics always be- come paralytic at the fame time with the cellular ones, by their greater fympathy with each other ? and hence the pau.city of urine, and the great thiril, diftinguiih this kind of dropfy ? 3. In the anafarca of the lungs, when the difeafe is not very great, though the patients have confi- derable difficulty of breathing at their firft lying down, yet after a minute or two their breath be- comes eafy again ; and the fame occurs at their firft rifmg. Is no,t this owing to the time neceffpry for 384 RETROGRADE ABSORBENTS. SECT. XXIX. 5. for the fluid in the cells of the lungs to change its place, fo as the leaft to incommode refpiratiorj in the new attitude ? 4. In the dropfy of the pericardium (Joes not the patient bear the horizontal or perpendicular atti- tude with equal eafe ? Does this circumftance dif- tinguifh the dropfy of the pericardium from that of the lungs and of the thorax? 5. Do the univerfal fweats diftinguifh the dropfy of the pericardium, or of the thorax? and thofe, which cover the upper parts of the body only, the anafarca of the Jungs? 6. W hen in the dropfy of the thorax, the patient endeavours to. lie down, does not the extravafated fiui comprefs the upper parts of the bronchia, and to- ally preclude the accefs of air to every part of the lungs ; whilft in the perpendicular attitude the inferior parts of the lungs only are comprefled f Docs not fometbing fimilar to this occur in the anafarca of the lungs, when the difeafe is very great, and thus prevent thofe patients alfo from lying down ? 7. As a principal branch of the fourth cervical nerve of the left fide, after having joined a brancl> of the third and of the fecond cervical nerves, de- fcending between the fubclavian vein and artery, is received in a groove formed for it in the peri- cardium, and is obliged to make a confiderable turn outwards to go over the prominent parj: of it, where the point of the heart is lodged, in its courfe to the diaphragm j and as the other phrenic nerve of the right fide has a ftraight courfe to the dia- phragm ; and as many other confiderable branches of this fourth pair of cervical nerves are fpread ori the arms ; does not a pain in the left arm diltin- guifh a difeafe of the pericardium, as in the angina pe&oris, or in the dropfy of the pericardium ? and does SECT. XXIX. 6. RETROGRADE ABSORBENTS. 38,5 does not a pain or weak nets in both arms diilin- guith the dropfy of the thorax ? 8. Do not -the drop Iks of the thorax and pericar- dium frequently ex: ft together, and thus and lo the uncertainty and 'fatality of the difeafe ? 9. Might not the foxglove be ferviceable in hy- drocephalus interims, in hydrocele, and in white f well ings of the joints ? , VI. Of cold Sweats. THERE have been hiftories given of chronical im- moderate fweatings, which bear fome analogy to the diabetes. Dr. Willis mentions a lady then living, whofe fweats were for many years fo pro- fufe, that all her bed-clothes were not only moift- ened, but deluged with them every night j and that many ounces, and fometimes -pints, of this fweat, were received in veflels properly placed, as it trick- led down her body. He adds, that (he had great thirft, had taken many medicines, and fubmitted to various rules of life, and changes of climate, but fiili continued jto have thefe immoderate fweats. Pharmac. ration, de fudore anglico. Dr. Willis has alfp obferved, that the fudor an- glicanus which appeared in England, in 1483, and continued till 1551, was in fome refpecls fimilar to the diabetes ; and as Dr. Gaius, who faw this dif- eafe, mentions the vifcidity, as well as the quantity of thefe fweats, and adds, that the extremities were often cold, when the internal parts wer£ burnt up with heat and third, with great and fpeedy emaci- ation and debility : there is great rcafon to believe, i hat the fluids were abforbed from the cells of the body by the cellular and cyftic branches of the lym- phatics, and poured on the fkin by the retrograde motions of the cutaneous ones. Sydenhara }S$ RETROGRADE ABSORBENTS. SECT. XXIX. 6, Sydenham has recorded, in the ftationary fever of the year 1685, the vifcid fweats flowing from the? bead, which w ere' probably from the fame fource, as thofe in the fweating plague above mentioned. It is very common in dropfies of the cheft or lungs to have the difficulty of breathing relieved by copious fweats, flowing from the head and neck. Mr. P. about 50 years of age, had for many weeks been afflicted with anafarca of his legs and thighs, attended with difficulty of breathing; and had re- peatedly been relieved by fquilj, other bitters, and chalybeates.— One night the difficulty of breathing became fq great, that it .was thought he mutt have expired ; but fo copious a fweat came out of his head and neck, that in a few hours fome pints, by eftimation, were wiped off from thofe parts, and his breath was for a time relieved. This dyfpncea and thefe fweats recurred at intervals, and after fome weeks he ceafed to exift. The fkin of his head and neck felt cold to the hand, and appeared pale at the time thefe fweats flowed fo abundantly'; which is a proof, that they were produced by an inverted motion of the abforbents of thofe parts ; for fweats, which are the confequence of an increafed a61ion of the fanguiferousfyftem,are always attended with) a warmth of the fkin, greater than is natural, ancl a more florid colour ; as the fweats from exercife, or thofe that fucceed the cold fits of agues. Can any one explain how thefe partial fweats fhould re- lieve the difficulty of breathing in anafarca, but by fuppoiing that the pulmonary branch of abforbents drank up the fluid in the cavity of the thorax, or in the cells of the lungs, and threw it on the fkin, by the retrograde motions of the cutaneous branch ? for, if we could fuppofe, that the increafed adion of the cutaneous glands or capillaries poured 'upon the fkin this fluid, previoufly abforbed from the Jungs ; why is not the whole furface of the body covered $tcT. XXIX. 6. RETROGRADE ABSORBENTS. 337 fcovered with fvveat ? why is not the {kin warm ? Add to this, that the fwears above-mentioned were clam- my or glutinous, which the condenfed perfpirable matter is not ; whence it would feem to have been a different fluid from that of common perfpira- tion. Dr. Dobfon, of Liverpool, has given a very inge- nious explanation of the acid fweats, which heob- ferved in a diabetic patient — he thinks part of the chyle is fecreted by the (kin, and afterwards under- goes an acetous fermentation. — Can the chyle get thither, but by an inverted motion of the cutane- ous lymphatics ? in the fame manner as it is carried .to the bladder, by the inverted motions of the uri- nary lymphatics. Medic. Obfervat. and Enq. Lon- don, vol. v. Are not the cold fweats in fome fainting fits, and in dying people, owing to an inverted motion of the cutaneous lymphatics ? for in thefe there can be no increafed arterial or glandular action. Is the difficulty of breathing, aiifing from ana- farca of the lungs, relieved by fweats from the head and neck; whilft that difficulty of breathing, which arifes from a dropfy of the thorax, or pericardium, is never attended with thefe fweats of the head ? and thence can thefe difeafes be diftinguifhed from each other ? Do the periodic returns of nocturnal afthma rife from a temporary dropfy of the lungs, collected during their more torpid Hate in found fleep, and then re-abforbed by the vehement efforts of the difordered organs of refpiranon, and carried off by the copious fweats about the head and neck? More extensive and accurate diffecYions of th< lymphatic fyflem are wanting to enable us to unravt fchefe knots of fcknce. VII. Translations 388 RETROGRADE ABSORBENTS. SECT. XXIX. 7. VII. Translations of Matter, of Chyle, of Milk, of Urine. Operation of purging Drugs applied exter- nally. 1. THE tranflations of matter from one part of the body to another, can only receive an explana- tion from the doctrine of the occafional retrograde motions of fome branches of the lymphatic fyiterri : for how can matter, abforhed and mixed with the -whole mafs of blood, be fo haftily ..collected again in any one part ? and is it not an immutable law, in animal bodies, that each gland can fecrete no other, but its own proper fluid ? which is, in part, fabri- cated in the very gland by an animal procefs, which it there undergoes: of thefe purulent tranflations innumerable and very remarkable inftances are re- corded. 2. The chyk, which is feen among the materials thrown up by violent vomiting, or in purging ftools, .can only come thither by its having been poured into the bowels by the inverted motions of the lac- teals : for our aliment is not converted into chyle in the ftomach or inteflines by a chemical procefs, but is made in the very mouths of the la&eals ; or iq. the mefenteric glands; in the fame manner as other fecreted fluids are made by an animal procefs in xheir adapted glands. Here a curious phenomenon in the exhibition of mercury is worth explaining : — If a moderate dole of calomel, or fix or ten grains, be fwallowed, and within one or two days a cathartic is given, a fali- vation is prevented : but after three or four days, a falivation having come on, repeated purges every day, for a week or two, are required to eliminate the mercury from the conflitution. For this acrid metallic preparation, being abforbed by the mouths of the Jackals, continues, for a time arrefted by the mefenteric SECT. XXIX. 7. RETROGRADE ABSORBENTS. 389 jnefenteric glands, (as the variolous or venereal poi- fons fwell the fubaxillar or inguinal glands) : which, during the operation of a cathartic, is returned into the inteitines by the inverted adion of the ladteals, and thus carried our of the fyftem. Hence we underftand the ufe of vomits or purges, to thofe who have fwallowed either contagious or poifonous materials, even though exhibited a day or even two days after fuch accidents ; namely, that by the retrograde motions of the ladteals and lym- phatics, the material ftill arrefted in the mefenteric, or other glands, may be eliminated from the body. 3. Many inftances of milk and chyle found in ulcers are given by Haller, EL Phyfiol. t. 7. p. i2y 23, \vhich admit of no other explanation than by fuppofing, that the chyle, imbibed by one branch of the abforbent fyftem, was carried to the ulcer, by the inverted motions of another branch of the fame fyftem. 4. Mrs. P. on the fecond day after delivery, was feized with a violent purging, in which, though opiates, mucilages, the bark, and teftacea were pro- fufely ufed, continued many days, till at length me recovered. During the time of this purging, no milk could be drawn from her J3reafts ; but the /tools appeared like the curd of milk broken into fmall pieces. In this cafe, was not the niilk taken up from the follicles of the pecloral glands, and thrown on the inteftines, by a retrogreffion of the inteftinal abforbents? for how can we ..for a moment fufpecl that tjie niucous glands of the inteftines could feparate pure milk from the blood ? Dr. Smel- ly has obferved, that loofe {tools, mixed with milk, which is curdled in the inteftines, frequently re- lieves the turgefcency of the breafts of thofe who ftudioufly repel their milk. Cafes in Midwifery, 43,, "No. 2. i. 5- J-F. RETROGRADE ABSORBENTS. SECT. XXIX. 7. 5. J. F. Meckel obferved in a patient, whofe urine was in fmall quantity and high coloured, that a copious fweat under the arm-pits, of a perfectly urinous fmell, ftained the linen ; which ceafed again when the ufual quantity of urine was difcharged by the urethra. Here we muft believe from analogy, that the urine was firft fecreted in the kidneys, then re-abforbed by the increafed aclion of the urinary lymphatics, and laftly carried to the axillae by the retrograde motions of the lymphatic branches of thofe parts. As in the jaundice it is necerTary, that the bile mould firil be fecreted by the liver, and re-abforbed into the circulation, to .produce the yel- lownefs of the ikin ; as was formerly demonflrated by the late Dr. Munro, (Edin, Medical Eflays) an4 if in this patient the urine had been re-abforbed into the mafs of blood, as the bile in the jaundice, why was it not detected in other parts ;of the body, as well as in the arm-pits ? 6. Cathartic and vermifuge medicines applied ex- ternally to the abdomen, feem to be taken up by the cutaneous branch of lymphatics, and pour- ed on the interlines by the retrograde motions of the lacleals, without having parted the circula* tion. *$$ For when the draftic purges are taken by the mouth, they excite the lacleals of. the intefl ines in- to retrograde motions, as appears frpm the chyle, which is found coagulated among the feces, as was ihewn above, »t(fecl. 2 and 4.) And as the cutane- ous lymphatics are joined with the la&eals of the interlines, by frequent anaflomofes; it would be more extraordinary, when a ilrong purging drug, abforbed by the ikin, is carried to the anaftomofmg branches of the lacleals unchanged, if it (hould not excite them into retrograde aftion--- as efficacioufly, StcT. XXIX. 8. RETROGRADE ABSORBENTS, 39t as if it was taken by the mouth, and mixed with the food of the flomach. VIII. Cimimjiances by which the Fluids, that are effii- fed by the retrograde Motions of the abforbent Vef- fels, are diftinguijhed. I. WE frequently obferve an unufual quantity of mucus or other fluids in fome difeafes, although the a n >t any quantity of any ilimulus, Which induces the veflels of animal bodies to revert their motions ; but a certain quan- tity of a certain itimulus, as appears from wounds in tlie ftomach, which do not produce vomiting 5 and wounds' of the inteftines, which do not produce the cholera morbus. At Nottingham, a few years ago, two fhoem\ke*-$ quarrelled, and one of them with a knife, which they ufe in their occupation, dabbed his companion about the region of the ftomach. On opening the abdomen of the wounded man after his death, the food and medicines he had taken were in part found in the cavity of the belly, on the outride of the bowels ; and there was a wound about half ari inch long at the bottom of the ftomach ; which I fuppofe was diftended with liquor and food at the time of the accident ; and thence was more liable to be injured at its bottom : but during the whole time he lived, which was about ten days, he had no efforts to vomit, nor ever even complained of being fick at the ftomach I Other cafes umitar to this are mentioned in the philofophical tranfadlions. Thus, if you vellicate the throat with a feather, naufea is produced \ if you wound it with a pen- knife, pain is induced, but not iicknefs. So it the foles of the feet of children or their armpits are tickled, oonvulfive laughter is excited, which ceafes the moment the hand is applied, fo as to rub them more forcibly, Dd The 39* RETROGRADE ABSORBENTS. SECT. XXIX. rr, The experiment therefore above related upon the la&eals of a dead pig, which were included in a ftritSt ligature, proves nothing ; as it is not the quan- tity, but the kind of ftimulus, which excites the lymphatic veflels into retrograde motion. XI. The Caufes which induce the retrograde Motions of animal Vejjels; and the Medicines by which the natu- ral Motions are rejlored. 1. SUCH is the conftru&ion of animal bodies, that all their parts, which are fubjecled to lefs ft i- muH than nature deligned, perform their functions with lefs accuracy : thus, when too watery or too acefcent food is taken into the ftomacb, indigeftion, and flatulency, and heart-burn fucceed. 2. Another law of iiritation, connate with our exiftence, is, that all thofe parts of the body, which have previoufly been expofed to too great a quantity of fuch ftimuli, as ftrongly affeafs, and forms another kind of jaundice, where the bile-du& is not quite paralytic, or has, regained its irritability. This difeafe is attended with much pain, which at firlt is felt at the pit of the ilomach, exactly ia the centre of the body, where the bile-duel: enters the duodenum ; afterwards, when the fize of the fcile^flones increafe, it is alfo felt on the right fide, where the gall-bladder is fituated. The former pain at the pit of the flomach recurs by intervals, as the bile-Hone is puttied againft the neck of the duct ; like the paroxyfrns of the flone in the urinary blad- der, the other is a more dull and conftant pain. Where thefe bile-ilones are too large to pafs, and the bile-dudis poffefs their fenfibility, this becomes a very painful and hopelefs difeafe. I made the fol- lowing experiments with a view to their chemical folution. ' Some fragments of the Tame bile-ftone were put pto the weak fpirit of marine fait, which is fold in the (hops, and into folution of mild alcali; and into a foluiion of cauftic alcali ; and into oil of turpen- tine; without their being diflblved. All thefe mix- tures were after fome time put into a heat of boil- ing Water, and then the oil of turpentine diflblved its fragment? of bile-ltone, but no alteration was produced upon thofe in the other liquids except Jo me change of their colour. Some fragments of the fame bile-done were put into vitriolic ssther, and were quickly diffolved with- out additional heat. Might not aether mixed with yolk of egg or with honey be given advantageoufir in bilious concretions ? I have in two inftances feen from 30 to 50 bile- ilones come away by llool, about the iize of large peas 404 PARALYSIS OF THE LIVER. SECT. XXX. r. peas, after having given fix grains of calomel in the evening, and four ounces of oil of almonds or olives on the fucceeding morning. I have alfo given half a pint of good olive or almond oil as an emetic during the painful fit, and repeated it in half an hour, if the firft clid not operate, with frequent good cffea. 4. Another difeafe of the liver, which I have feveral times obferved, confifts in the inability or paralyfis of the fecretory .veifels. This aifeafe has generally the fame eaufe as the preceding one, the too frequent potation of fpirituous liquors, or the too fudden omiflion of them, after the habit is con- firmed ; as is greater or lefs in proportion, as the whole or a part of the liver is affected, and as the inability or paralyfis u more or lefs complete. This palfy of the liver is known from thefe fymp- torm, the patients have generally pafled the meridian of life, have drank fermented liquors daily, but perhaps not been opprobrious drunkards ; they lofe their appetite, then their flefh and ftrength dimi- nifh in confequence, there appears no bile in their flools, nor in their urine, nor is any hardnefs or fwelling perceptible on the region of the liver. But •what is peculiar to this difeafe, and diftinguifhes it from all others at the firft glance of the eye, is the bombycinous colour of the {kin, which, like that of full-grown iilkworms, has a degree of tranfpa- rency with a yellow tint not greater than is natural to the ferum of the blood. Mr. C. and Mr. B. both very ftrong men, be- tween 50 and 60 years of ige, who had drank ale at their meals inftead of fmail beer, but were not reputed hard drinkers, fuddenly became weak, loft their appetite, flefh and fbength, with all the fymp- toms above enumerated, and died in about two months from the beginning of their malady. Mr. C. became anaiarcous a few days before his death, and. SECT. XXX. i. PARALYSIS OF THE LIVER. and Mr. B. had frequent and great haemorrhages from an iflue and fome parts of his mouth, a few days before his death. In both thefe cafes calomel, bitters and chalybeates were repeatedly ufed with- out effecl. ' One of the patients defcribed above, Mr. G. was by trade a plumber ; both of them could digeft no food, and died apparently for want of blood. Might not the transfufion of blood be ufed in thefe cafes with advantage ? 5. When the paralyfis of the hepatic glands is Jefs complete, or lefs univerfal, a fchirrofity of fome part of the liver is induced ; for the fecretory vef- fels retaining fome of their living power take up a fluid from the circulation, without being fufficiently irritable to cany it forwards to their excretory duds; hence the body, or receptacle of each gland, be- comes inflated, and this diftenfion increafes, till, by its very great ftimulus inflammation is produced, or till thofe parts of the vifcus become totally paraly- tic. This difeafe is diftinguifhable from the fore- going by the palpable hardnefs or largenefs of the liver; and as the hepatic glands are not totally para- lytic, or the whole liver not atfec"led, fome bile con- tinues to be made. The inflammations of this vifcus, confequent to the fchirrofity of it, belong to the difeafes of the fenfuive motions, and will be treated of hereafter. 6. The ancients are faid to have poffefled an art of increafing the livers of geefe to a fize greater 'than the remainder of the goofe. Martial. 1. 13. epig. 58. — This is faid to have been done by fat and fig*. Horace, 1. 2. fat. 8.— Juvenal fets thefe large Jivers before an epicure as a great rarity. Sat. 5. 1. 114; and Perfius, "fat. 6. 1.71. Pliny fays thefe large goofe-livers'were foaked in mulled milk, that is, I fappofe, milk mixed with honey and wine ; and "adds, but who can neverthelefs bear 4*6 DISEASES OF IRRITATION. SECT. XXXII. 3. bear the more temperate coldnefs of Buxton bath, which is about eighty degrees of heat, and which ftrengthens them, aud makes them by habit lefs lia- ble to great quiefcence from fmall variations of cold, and thence lefs liable to be difordered by the unavoidable accidents of life. Hence it appears, why people of thefe inirritable conftituticns, which is another expreffion for fenforial deficiency, are often much injufed by bathing in a cold fpring of water ; and why they mould continue but a very fhort time in baths, which are colder than their bodies ; and flioul4 gradually increafe both trre de- gree of coldnefs of the water, and the time of their continuance in it, if they would obtain falutary ef- fects from cold immerfions. See Se6t. XII. 2. i» On the other hand, in all cafes where the heat of the external furface of the body, or of the inter- nal furface of the lungs, is greater than natural, the ufe of expofure to cool air may be deduced. In fever-fits attended with ftrength, that is with great quantity of fenforial power, it removes the additional ftimulus of heat from the furfaces above- mentioned, and thus prevents their excefs of ufe. lefs motion ; and in fever-fits attended with debi- lity, that is with a deficiency of the quantity of fenforial power, it prevents the great and dangerous wafte of fenforial power expended in the unnecef- fary increafe of the actions of the glands and capil- laries of the (kin and iungs. 4. In the fame manner, when any one is long cxpofed to very cold air3 a quiefcence is produced of the cutaneous and pulmonary capillaries and ab- forbents, owing to the deficiency of their ufual fti- mulus of heat ; and this quiefcence of fo great a quantity of veffels affects, by irritative aflbciation, the whole abforbent and glandular fyflem, which becomes in a greater or lefs degree quiefcent, and a cold fit of fever is produced, If . XXXII. 4. DISEASES OF IRRITATION. 427 It the deficiency of the ftimulus of heat is very great, the quiefcence becomes fo general as to ex- tinguifh life, as in thofe who arc frozen to death. If the deficiency of heat be in lefs degree, but yet fo great as in fome meafare to diforder the fyftem, and fhould occur the fucceeding day, it will induce a greater degree of quiefcence than before, from its acting in concurrence with the period of the diurnal circle of actions, explained in Seel:. XXXVf. Hence from a fmali beginning a greater and greater degree of quiefcence may be induced, till a complete fever-fit is formed ; and' which will continue to recur at the periods by which it was produced. See Seel. XVIL 3. 6. If the degree of quiefcence occafioned by de- fect of the itimulus of heat be very great, it will recur a fecond time by a (lighter caufe, than that which firft induced it. If the caufe, which induces the fecond fit of quiefcence, recurs the fucceed- ing day, the quotidian fever is produced ; if not till the alternate day, the tertian fever ; and if not till after feventy-two hours from the firft fit of quief- cence, the quartan fever is formed. This laft kind' of fever recurs lefs frequently than the other, as it is a difeafe only of thofe of 'the temperament of affociability, as mentioned in Seet. XXXI. ; for in other conftitutions the capability of forming a habit ceafee, before the new caufe of quiefcence is again applied, if that does not occur fooner than in feventy-two hours .And hence thofe fevers, whofe caufe is from cold air of the night or morning, are more liable to obferve the folar day in their periods ; while thofe from other caufes frequently obferve the lunar day in their periods, their paroxyfms returning' near an: hour later every day, as explained in Seel. XXXVI. IV. Another frequent caufe of the cold fits of fever is the defect of the ftimulus of diftentioh. F f The 4*8 DISEASES OF IRRITATION. SECT. XXXII. 4 The whole arterial fyftem would appear, by the ex- periments of Haller, to be iiritable by no other flimulus, and the motiont of the heart and ali- mentary canal are certainly in fome meafure de- pendant on the fame caufe. SeeSe&.XIV. 7. Hence there can be no wonder, that the diminution of detention fhould frequently induce the quiefcence, which Conftitutes the beginning of fever-fits. Monfieur Leiutaud has judicioufly mentioned the deficiency of the quantity of blood amongft the caufes of difeafes, which he fays is frequently evi- dent in diiTeclions : fevers are hence brought on by great haemorrhages, diarrhoeas, 01 other evacuations; or from the continued ufe of diet, which contains but little nourifhment; or from the exhauftion oc caiioned by violent fatigue, or by thofe chronic dif cafes in which the digeftion is much impaired ; ai where the ftomach has been long affe&ed with th< gout or fc birr us ; or in the paralyfis of the liver, as deferibed in Sedt. XXX. Hence a paroxyfm o; gout is liable to recur on bleeding or purging ; as the torpor of fome vifcus, which precedes the in flamma'tion of the foot, is thus induced by the want of the ftimulus of diftention. And hence the e>; tremities of the body, as the nofe and fingers, are more liable to become cold, when we have long abftained from food; arid hence the pulfe is increaf- ed both in ftrength and velocity above the natural Ihndard after a full meal by the ftimulus of dif- tention. However, this ftimulus of diftention, like th ftimulus of heat above defcribed, thougb it contr butes much to the due adlion not only of the heart, arteries, aud alimentary canal, but feems neceflary to the proper fee ret ion of all the various glands ; yet perhaps it is not the fole caufe of any of thele numerous motions: for as the lacleals, cutaneous abforbents, and the various glands appear to be (Umulaied SECT. XXXII. 5. DISEASES OF IRRITATION. 429 Simulated into acYion by the peculiar pungency of the fluids they abforb, fo in the inteilinal canal the., pungency of the digefting aliment, or the acrimony of the faeces, ieein to contribute, as well as their bulk, to promote the periftaltic motions ; and in the arterial fyftem, the momentum of the particles of the circulating blood, and their. acrimony, ftimulate the arteries, a$ well as the diftenUon occafioned by. it. ., Where the pulfe is fmall this defeci of dif- tentiott is prefent, and. contributes much, tQ pro- duce the febris irritativa pulfu debili, or irritative fever with weak pulfe, called by modern writers nervoits fever,, as a predifponent caufe. See Sec"t. XII. I. 4. Might not the transfufion of blood, fuppoie of four ounces daily from a ftrong man, or other healthful animal, as a fheep or an afs, be ufed in the early ftate of nervous or putrid fevers with great profpc£l of fuccefs ? V. The defed of the momentum of the particles of. the circulating blood is another caufe of the quiefcence., . with which the cold fits of fever com- mence. This ftimulus of the mpmentuin of the pro- greflive particles of the blood docs not aft over the whole body like thofe of heat and diflention above defcribed; but is confined to the arterial fyf- tern ; an'd differs from, the ftimulus of the detention of the bloody as much as the vibration of the air does from the currents of it. Thus are the dif- ferent organs of our bodies ftimulated by four dif- ferent mechanic properties of the exteirial world : the fenfe of touch by the predu.re of folid bodies fc> as to diftinguifh their figure; the mufcular fyf- tem by the diftention, which they . occaiion ; the internal furface of the arteries, by the .momentum of their moving particles; and the auditory nerves, by the vibration of them : and thefe four mechanic properties are as different from each, other as the F f % various 43$ DISEASES OF IRRITATION. SECT. XXXII. $, various chemical ones, which are adapted to the numerous glands, and to the other organs of fenfe. 2. The momentum of the progreflive particles of blood is compounded of their velocity and their quantity of matter : hence whatever circumftances dirninim either of thefe without proportionally in- creaiing the other, and without fuperadding either of the general ftimuli of heat or diftention, will tend to produce a qinefcence of the arterial fyftem, and fiorn thence of all the other irritative motions, which are connected with it. Hence in all thofe confutations or difeafes where t'he blood contains a greater proportion of ferum, which is the lighteft part of its composition, the pulfations of the arteries are weaker, as in nervous levers, chlorolis, and hyfteric complaints ; for in thefe cafes the momentum of the progreflive parti- cles of blood is lefs : and hence, where the denfer parrs of its compolition abound, as the red part of if, or the coagulable lymph, the arterial pulfati- ons are (honger 5 as in thofe of robuft health, and in inflammatory difeafes. That this ftrmulus of the momentum of the par- ticles of the circulating fluid is of the greateft con- feqnence to the arterial aclion, appears from the experiment or injeding air into the blood veflels, \vhichfeems to deftroy animal life from the want of this ftimulus of momentum ; for the diftention of the arteries is not diminiihed by it, it poiTerTes no corrofive acrimony, and is lefs liable to repafs the valves than the blood itfelf ; iince air-valves in all machinery require much lefs accuracy of con- flruction than thofe uhich are oppofed to water. 3. One method of recreating the velocity of the blood, and in confequence the momentum of its particles, is by the exercife of the body, or by the fusion of its furface : fo, on the contrary, too great indolence contributes to decreafe this ftimulus of SECT. XXXII. 6. DISEASES OF IRRITATION. 43r of the momentum of the particles of the circulating blood, and thus tends to induce quiefcence : as is feen in hylleric cafes, and chlorous, and the other, difeafes of fedentaiy people. 4. The velocity ol the particles of the blood in certain circumilances is increafed by venefe&ion, which, by removing a part of it, diminishes the re- iiftance to the motion of the other part, and hence jthe momentum of the particles of it is increafed. This may be eaiily undeiftood by confidering it in the extreme, fmce, if the refiftance was greatly in- creafed, fo as to overcome the propelling power, there could be no velocity, and in confequence no momentum at all. From this circumftance arifes that curious phenomenon, the truth of which I nave been more than once witnefs to, that vene- leclion will often iqftantaneoufly relieve thofe ner- vous pains, which attend the cold periods of hyfle- lic, afthmatic, or epileptic difeaies ; and that even •where large dofes of opium have been in vain ex- hibited. In thefe cafes the pulfe becomes ilronger after the bleeding, and the extremities regain their natural warmth ; and an opiate then given a6ts with much more certain effecl:. VI. There is another caufe, which feems pccafi- pnally to induce quiefcence into fome part of our fyftem, I mean the influence of the fun, ^nd moon; the attraction of thefe luminaries., by de- creafing the gravity of the particles of the blood, cannot aifeft their momentum, as their vis inertia: remains the fame ; but it may neverthelefs produce fome chemical change in them, becaufe whatever affe&s the general attractions of the particles of matter may be fuppofed from analogy to affect their fpecific attradions or affinities : and thus the flimulus of the particles of blood may be dimi- nifhed, though not their momentum. As the tides of the fea obey the fouthing and northing of the moon 4|a DISEASES OF IRRITATION. SECT. XXXI). t. moon (allowing for the time necefTary for their xriotion, and the obihucYions of the fhores), it is probable, that there are alib atmofpheric tides on both fides of the earth, which to the inhabitants of another plane* might fo defied the Jight as to referable the ring of Saturn. Now as thefe tides of water, or of air, are railed by the diminution of their gravity, it follows, that their preffure on the furface of the earth is no greater than the preffure of the other parts of the ocean, or of the atmofphere, where no fuch tides exift ; and^there- fore that they cannot affeclt the mercury in the barometer. In the fame manner, the gravity in all ^ther terreftrial bodies is cjiminifhed at the times pf the fouthing and northing of the niopn, and that ma greater degree w.htn- this coincides- with the ibuthing and northing of the fun^ and this in a ftill greater degree about the times of the equi- noxes* This decreafe of the gravity of all 'bodies during the time the moon pafTes our zenith^ 'or nadir might poffibly be fhewn by the flower vi- brations of a pendulum,- compared with a fpring clock, or with : aftronomjcal obfervation. Since a pendulum of a certain length moves flower at the line than near the poles, becaufe the gravity being diminifhed and the vis inertias continuing the fame, the motive power is lefs, but the refinance to be overcome continues the fame. Tfie combined pow- ers of the lunar and folar attraction is eftimated by Sir Ifaac Newton not to exceed one 7,868, §5oth part of the power of gravitation, which feems in- deed but a fmail circumftance to prpduce any con- iiderable effedj: on the weight of fublunary bodies, and yet this is fufficienjt to raife the tides at the equator above ten feet high ; and if it be conii- dcred, what frnall impulfes of other bodies produce their effedls on the organs of fenfe adapted to the perception of them, as of vibration on the aucji- tdrjr . XXXII. 6. DISEASES OF IRRITATIO^. 433 nerves, we fliall ceafe to be furprifed, that fo minute a diminution in the gravity of the par- ticles of blood fhou}d fo far affect their chemical changes, or their ftimujating quality, as, joined with other caufes, fqme.tirnes to produce the beginnings of difeafes. Add to this, that if .the lunar influence produ- ces a very fmgll degree of quiefcencq at firft, and if that rcjcurs #t certain periods even with lefs power to produce quiefcence than at firft, yet the quiefcence will daily increafe by the acquired habit a6lingat the fame time, till at length fo great a degree of quiefcence is induced as to produce phrenfy, canine madnefs, epilepfy, hyfteric pains or cold fits of fever, inflances of many of which are to be found in Dr. Mead's W9rk on this f ab- ject. The folar influence alfo appears daily in fe- yeral difeafes; but as darknefs, filence, fleep, and our periodical meals mark the parts of the folaf circle of actions, it is fometimes dubious to wliich of thefe the periodical returns of thefe difeafes ar$ to be afcribed. As far as I have been able tp obferve, the pe- riods of inflammatory difeafes obferve the folar day ; as the gout and rheumatifm have their greateft quiefcence about noon and midnight, and their ex- acerbations fome hours after ; as they have more frequently their immediate caufe from cold air, in- .anition, or fatigue, than from the effe£l of luna- tions : whilft the cold fits of hyfleric patients, and thofe in nervous fevers, more frequently occur twice a day, later by near half an hour each time, according to the lunar day ; w hi 1ft fonie fus of intermittents, which are undifturbpd by medi- cines, return at regular folar periods, and others at lunar ones ; which may, probably, be owing to the difference of the periods of thofe external cir- cumftances 434 DISEASES OF IRRITATION. SECT. XXXU. p. cumftances of cold, inanition, or lunation, which immediately caufed them. 'v We muft, however, oWerve, that the periods of quiefcence and exacerbation in difeafes do not always commence at the time&'of the fyzygies or 'quadratures of the' moon and fun, or at the times of their pafling the zenith or nadir; but as it is probable, that the ftimulus of the particles of the circumfluent blood is gradually diminifhed from the time of the quadratures to that of the fyzy- gies, the quiefcence may commence at any hour, when co-operating with other caufes of quiefcence, it becomes great enough to produce a difeafe : afterwards it will Continue to recur at the fame 'periods of the lunar or folar influence; the fame caufe operating conjointly with the acquired habit, that is with the catenation of this new motion 'with the difTevered links of the lunar or folar cir- cles of animal a&ion. In this mariner the periods of menftruation obey the lunar month with great exadtnefs in healthy pa- tients (and perhaps the venereal orgafm in brute animals does the fame), yet tjiefe periods do not commence ' either at the fyzygies or quadratures t)f the lunations/ but at whatever time of the lunar periods they begin, they obferve the fame in their returns till fome greater caufe diflurbs them. Hence, though the bell way to calculate the time of the expected returns of the paroxyfms of peri- odical difeafes is to count the number of hours between the commencement of the two preceding fits, yet the following obfervations may be worth attending to, when we endeavour to prevent the returns of maniacal or epileptic difeafes ; whofe periods (at the beginning of them efpecially) fre- quently obferve the fyzygies of the moon an4 'fun, and particularly about the equinox. The greateft of the two tides happening in every , * *-M revolution . XXXII. 7* DISEASES OF IRRITATION. 435 revolution of the moon, is that when the moon ap- proaches neareft to the zenith or nadir ; for this reafon, while the fun is in the northern ligns, that is during the vernal and fummer months, the greater of the two diurnal tides in our latitude is that, when the moon is above the horizon ; and when the fun is in the fouthern figns, or during the autumnal and winter months, the greater tide is that, which arifes when the moon is belo\v the horizon : and as the fun approaches fomewhat nearer the earth in winter than in fummer, the greateft equinoctial tides are obfervcd to be a little .before the vernal equinox, and a little after the autumnal one. Do not the cold periods of lunar difeafes com- mence a few hours before the fou thing of the moon during the vernal and fummer months., and before the northing of the moon during the au- tumnal and winter months ? Do not palfies and apoplexies, which occur about the equinoxes, happen a few days before the vernal equinoctial Junation, and after the autumnal one ? Are not the periods of thofe diurnal difeafes more obftinate, that commence many hours before the fouthing or northing of the moon, than of thofe which commence 'at thofe times? Are not thofe palfies and apoplexies more dangerous which commence many days before the fyzygies of the moon, than thofe which happen at thofe times? See Se6l. JCXXVI. on the periods of difeafes. VII. Another very frequent caufe of the cold fit of fever is the quiefcenceef fome of thofe large Congeries of glands, which compofe the liver, fpleen, or pancreas; one or more of which are frequently fo enlarged in the autumnal intermit- tents as to be perceptible to the touch externally, and are called by the vulgar ague-cakes. As thefe glands are flimulated into a&ion by the fpccific pungency DISEASES OF IRRITATION. SECT. XXXII.?. pungency of the fluids, which they abforb, the/ general caufe of their quiefcence feems to be i^e too great inlipidity of the fluids of the body, co- operating perhaps at the fame time with other ge- neral caufes of quiefcence. Hence, in mariliy countries at cold feafons, which have fucceeded hot ones, and amongft thofe, who have lived on innutritious and unfti ululating diet, thefe agues are mod frequent. The enlarge- ment of thefe quiefcent vifcera^and the Iwelling of the prsecordia in many other fevers, is,, mod pro- bably, owing to the fame caufe; which may confiil in a general efficiency of the production of fenio- rial power, as well as in the diminifhed Simulation of the fluids ; and wh.ep the quieicence of fo great a number of glantjs, as conftitute one of thofe Jarge vifcera, commences, all the other irritative motions are aije$:ed by their connexion, with it, and the cold fit of fever is prgduced. VIII. There are many other caiife$3 which pro- duce quiefcence of fpme part of the animal fyftem, as fatigue, hunger, thirft, bad djet, difappointed love, unwhoiefome air, exhauftion from evacua- tions, and many others ; but the lad caufe, that we thall mention, as frequently productive of cold fits of fever, is fear or anxiety of mind. The pains, which we are firft and moil generally ac- quainted with, have been produced by defect of fome (limulus ; thus, foon after our natiyity \vef become acquainted with the pain from tl)e;? cold- nefs of the air, from the want of refpiration, and. from the want of food. Nqw §1J tjiefe pain? pcca{ floned by defect of ilimulus are attended withqui- cfcence of the organ, and at the fame, time with a greater or lefs degree of quiefcence of other parts of the fyftem : thus, if we even endure the^ pain of hunger fo as to mifs one meal inflead of our daily habit of repletion, not only the perif- taltic motions of the ftomach and bowels are di- miniiliecj SfiCT.X3fXlI.9- DISEASES OF IRRITAf ION. 437 minifhed, but we are more liable to coldnefs of our extremities, as of our nofes, and cars, and feet, than at other times. Now, as fear is originally excited by our hav- ing experienced pain, and is itfelf a painful affec- tion, the fame quieicence of other fibrous motions Accompany it, as have been mod frequently con- nected with this kind of pain, as explained in Seel. XVI. 8 i. as the coldnefs and palenefs of the ikin, trembling, difficult refpiration, indigef- tion, and other fymptoms, which contribute to form the cold fit of fevers. Anxiety is fear con- tinued through a longer time, and, by producing chronical torpor of the fyftem, extinguimes life /lowly, by what is commonly termed a broken heart. IX. I. We now Hep forwards to coniider the other fymptoms in confequenpe of the quicfcence which begins the fits of fever. If by any of the circumftances before defcribed, or by two or more of them a6ling at the fame time, a great degree of quiefcence is induced on any confiderable part of the circle pf irritative motions, the whole clafs of them is more or lefs cjifturbed by their irrita- tive aflfociations. If this torpor be occafioned by a deficient fupply of fenforial power, and happens to any of thofe parts of the fyftem, which are ac- cuftomecj to perpetual a&ivity, as the vital motions, the torpor ihcreafes rapidly, becaufe of the -great ex- penditurp of fenforial power by the in ceilant acti- vity' pf T t)iofe ' parts of the fyilem, as fhewn in No. 3-2. of this Sedlion. Hence a deficiency of all the fecretions facceeds, and as animal heat is produced in proportion to the quantity of thofe fecretions, the coldnefs of the fkin is the firft circumdance, which is attended to. Dr. Martin aliens, that fome parts of his body were warmer than natural in the cold fit of fever ; but it is certain, that thofe which are uncovered, as the fingers, and nofe, and ears, are much colder to the touch, and paler in appearance. It is pofli- blc 438 DISEASES OF IRRITATION. SECT. XXXII.9: i>le, that his experiments were made at the be- ginning of the fubfequent hot fits; which com- mence with partial diftrifeutions of heat, owing to fome parts of the body regaining their natural irritability fooner than others. From the quiefcence of the anaftomoflng capil- laries a palenefs pf the fkin fucceeds, and a lefs fecretion of the perfpirable matter ; from the qui- efcence of the pulmonary capillaries a difficulty of refpiration arifes ; and from the quiefcence of the other glands lefs bile, lefs gaftric and pancrea- tic juice, are fecreted into the ftomach and intef- tines, and lefs mucus and faliva are poured into the mouth ; whence arises the dry tongue, cof- tivenefs, dry ulcers, and paucity of urine. From the quiefcence of the abforbent fyflem arifes the great thirft, as lefs moifture is abibrbed from the atmofphere. The abforption from the atmofphere was obferved by Dr. Lyfter to amount to eighteen ounces in one night, above what he had at the fame time infenfibly perfpired. See Langrifh, On the fame account the urine is pale, though in fmall quantity,' for the thinner part is not abforbed from it; and when repeated ague fits continue long, the legs fwell from the diminifhed 'abforp- tion of the cellular abforbents. From the quiefcence of the inteftinal canal a lofs of appetite and flatulencies proceed. From the partial quiefcence of the glandular vifcera a fuelling and teniion about the pr2ecordia becomes fenfible to the touch ; which is occafioned by the delay of the fluids from the defe£l of venous or lymphatic abforption. The pain of the forehead, and of the limbs, and ef the fmall of the back, arifes from the quiefcence of the membranous fafcia, or mufcles of thofe parts, in the fame man- ner as the Ikin becomes painful, when the vefiels, of which it is compofed, become quiefcent from cold SECT. XXXII. 9. DISEASES OF IRRITATION 439 cold. The trembling in confequence of the pain of coldnefs, the reftleflhefs, and the yawning, and ftretching of the limbs, together with the Ihud- dering, or rigours, are convuliive motions ; and will be explained amongft the difeafes of voli- tion ; Sea. XXXIV. , Sicknefs and vomiting is a frequent fymptom in the beginnings of fever-fits, the mufcular fibres of the ftomach fhare the general torpor and debi- lity of the fyftem ; their motions become firft leffened, and then flop, and then become retro- grade ; for the acl of vomiting, like the globus hyftericus and the borborigmi of hypochondriacs, is always a fymptom of debility, either from want of ftimulus, as in hunger ; or from want of fen- forial power, as af er intoxication ; or from fym- pathy with fome other torpid irritative motions, as in the cold fits of ague. See Sect. XII. 5. 5. XXIX. 11. and XXXV. i. 3. where this aft of vo- miting is further explained. The fmall pulfe, which is faid by fome writers to be flow at the commencement of ague-fits, and which is frequently trembling and intermittent, is owing to the quiefcence of the heart and arterial fyftem, and to the refiftance oppofed to the cir- culating fluid from the inactivity of all the glands and capillaries. The great weaknefs and inability to voluntary motions, with the infenfibility of the extremities, are owing to the general quiefcence of the whole moving fyftem ; or perhaps, fimpiy to the deficient production of fenforlal power. If all thefe fymptoms are further increafed, the quiefcence of all the mufcles, including the heart and arteries, becomes complete, and death enfues. This is, moft probably, the cafe of thofe who are ftarved to death with cold, and of thofe who are faid to die in Holland from long fkaiting on their frozen canals. 2. As 44* DISBARS OF IRRITATION. SECT. XXXII 9. 2. As foon as this general quiefcence of the* fyftem. ceafes, either by the diminution of the caufe, or by the accumulation of fenforial power, (as in fyneope, Sect. XII. 7. i.). which is the na- tural confequenee of previous quiefcence, the hot fit commences. Every gland of the body is .now ftimulaied into ftfoflgfcr £6tion than is" natural, as its irritability- is increafed by accumulation of fenforial power during its late quiefcence, a fuper- abu'hdan'ce of all the fecretions is produced, and an increafe of heat hi confequence of the increafe of thefe fec?etio'ns. The fkin becomes red, and the perfpitation great, owing to the increafed action of the capillaries during the hot part of the paroxyfm. The fecretion of perfpirable matter is perhaps great- er during the hot fit than In the fweating fit, which follows; but as the abforpticn of it alfo is greater, it does not ftand on the fkin in vifible dro'ps : add to this, that the evaporation of it is aifo greater, from the increafed heat oF the fkin. But at the decline of the hot fit, as the mouths of the abfor- bents of the fkin are expofed to the cooler air, or bed-clothes, thefe velfels fooner lofe their increafed activity, and ceafe to abforb more than their natural quantity : but the fecerning veffels for fome time longer, being kept warm by the circulating bloody continue to pour out an increafed quantity of per- fpirable matter, which now Hands on the fkin^ in large virible drops ; the exhalation of it alfo being leflened by the greater coolnefs of the fkin, as well as its abforpfion by the dimimfhed action of the lymphatics. See Giafs I. 1. 1. 3. The incieafed fecretion of bile and of other flu- ids poured into the inteflines frequently induce a purging at the decline of the hot fit; for as the external abforbent veffels have their mouths ex- pofed to the cold air, as above mentioned, they ceafe to be excited into unnatural activity fooner tharj SECT.XXXU. 9. DISEASES OF IRRITATION. than the fecretory veffels, whofe mouths are expofed to the waniith of the blood : now, as the internal abforbents fympathize with the external ones, thefe alfo, which during the hot fit drank up the thin- ner part of the bile, or of other fecreted fluids, lofe their incieafed activity before the gland loles its increafed activity, at the decline of the hot fit ; and the loofe dejections are produced from the fame caufe, that the incieafed perfpiration Hands on the fmfa^e of the fkin, from the increafed ab- ibrption ceafing iboner than the incieafed fecre- tion. The urine during the cold fit is in fmall quan- tity and pale, both from a deficiency of the fecre- tion and a deficiency of the abforptton. During the hot fit it is in its ufual quantity, but very high- coloured and turbid, becaufe a greater quantity had been fecreted by the increafed action of the kid- riies, and alfo a greater quantity of its more aque- ous part had been a bfoi bed from it in the bladder by the increafed aclion of the abforbents ; and laftly, at the decline of the hot fit it is in large quantity and lefs coloured, or turbid, becaufe the abforbent vefTels of the bladder, as obferved above, lofe their increafed action by iympathy with the cutaneous ones fooner than the fecretory veffels of the kidnies lofe their increafed activity. Hence the quantity of the fedimenf, and the colour of the urine, in fevers, depend much on the quantity fe- creted by the kidnies, and the quantity abforbed from it again in the bladder : the kinds of fedi- ment, as the lateritious, purulent, mucous, or -Woody lediments, depend on other caufes. It fhould *be obferved, that if the fweating be incieafed by the heat of the loom, or of the bed-clothes, a paucity of turbid urine will continue to be pn> duced, as the abforbents of the bladder will have their activity increafed by their fympathy with the veflela 44* DISEASES OF IRRITATION. SECT. XXXII. 9. veflels of the fkin, for the purpofe of fupplying the fluid expended in perfpi ration. The pulfe becomes itrong and full, owing to the increafed irritability of the heart and arteries, from the accumulation of fen fo rial power during their quiefcence, and to the quicknefs of the return of the blood from the various glands and capillaries. This increafed action of all the fecretory . veflels does not oecur veiy fuddenly, nor univerfally at the fame time. The heat feems to begin about the center, and to be diffufed from thence irregularly to the other parts of the fyflem. This may be owing to the fituation of the parts which firft be- came quiefcent and caufed the fever-fit, efpecially when a hardnefs of tumour about the praecordia can be felt by the hand ; and hence this part, in whatever vifctis it is feated, might be the firfl to regain its natural or increafed irritability. 3. It mud be here noted, that, by the increafed quantity of heat, and of the impulie of the blood at the commencement of the hot fit, a great in- creafe of itimulus is induced, and is now added to the increafed irritability of the fyflem, which was occafioned by its previous quiefcence. This addi- tional flimulus of heat and momentum of the blood' augments the violence of the movements of the ar- terial and glandular fyftem in an increafing ratio. Thefe violent exertions flili producing more heat and greater momentum of the moving fluids, till at length the fenforial power becomes walled by this great ftimulus beneath its ufual quantity, and pre- difpofes the fyflem to a fecond cold fit. At length all thefe unnatural exertions fpontane- ouily fubfide with the increafed irritability that pro- duced them ; and which was itfelf produced by the preceding quiefcence, in the fame manner as the eye, on coming from darknefs into day-light, in a" little time ceafes to be dazzled and pained, and gradually SBCT. XXXII. 10. DISEASES OF IRRITATION. 445 gradually recovers its natural degree of irritabi- lity. 4. But if the increafe of irritability, and the con- fequent increafe of the itimulus of heat and mo- mentum, produce more violent exertions than thofe above defcribed ; great pain arifes in fome part of the moving fyftem, as in the membranes of the brain, pleura, or joints ; and new motions of the veflels are produced in coniequence of this pain, which are called inflammation ; or delirium or ftu- por arifes ; as explained in Sect. XXI. and XXXIII. : for the immediate effect is the fame, whether the great energy of the moving organs arifes from an increafe of ftimulus or an increafe of irritability ; though in the former cafe the waile of fenforial power leads to debility, and in the latter to health. Recapitulation. X. Thofe mufcles, which are lefs frequently ex- erted, and whofe actions are interrupted by fleep, acquire lefs accumulation of fenforial power during their quiefcent ftate, as the mufcles of locomotion. In thefe mufcles after great exertion, that is, after great exhauftion of fenforial power, the pain of fa- tigue enfues ; and during reft there is a renovation of the natural quantity of fenforial power; but where the reft, or quiefcence of the mufcle, is long continued, a quantity of fenforial power becomes accumulated beyond what is neceflary ; as appears by the uueafmefs occafioned by want of exercife'; and which in young animals is one caufe exciting them into action, as is feen in the play of puppies and kittens. But when thofe mufcles, which are habituated to perpetual actions, as thofe ot the ftomach by the ftimulus of food, thofe of the veflels of the (kin by G g the 444 DISEASES OF IRRITATION. SECT. XXXII. 10. the ftimulus of heat, and thofe which conftitute the arteries and glands by the fiimulus of the blood, be- come for a time quiefcent, from the want of their ap- propriated ftimuli, or by their aflbciations with other quiefcent parts of the fyftem ; a greater accumula- tion of fenforial power is acquired during their qui- efcence, and a greater or quicker exhauftion is pro- duced during their increafed aclion. This accumulation of fenforial power from defi- cient action, if it happens to the ilomach from want of food, occafions the pain of hunger ; if it happens to the veffels of the fkin from want of heat, it oc- cafions the pain of cold ; and if to the arterial fyftem from the want of its adapted ftimuli, many difagreeable fenfations are occafioned, fuch as are experienced in the cold fits of intermittent fevers, and are as various, as there are glands or membranes in the fyftem, and are generally termed univerfai uneafinefs. When the quiefcence of the arterial fyftem is not owing to defed of ftimulus as above, but to the de- fective quantity of fenforial power, as in the com- mencement of nervous fever, or irritative fever with weak pulfe, a great torpor of this fyftem is quickly induced ; becaufe both the irritation from the fti- mulus of the blood, and the aflbciation of the vaf- cular motions with each other, continue to excite the arteries into action, and thence quickly exhauft the ill-fupplied vafcular mufcles ; for to reft is death ; and therefore thofe vafcular mufcles continue to pro- ceed, though with feebler adtion, to the extreme of wearinefs or faintnefs ; while nothing fimilar to this affects the locomotive mufcies, whofe addons are ge- nerally caufed by volition, and not much fubjecl: either to irritation or to other kinds of aflbciations befides the voluntary ones, except indeed when they are excited by the lafh of flavery. In SECT. XXXII, 10. DISEASES OF IRRITATION; 44$ In thefe vafcular mufcles, which are fubject to perpetual a&ion, and thence liable to great accumu- lation of fenforial power during their quielcence from want of ftimulus, a great increafe of activity occurs, either from the renewal of their accuitom- ed ilimulus, or even from much lefs quantities of ftimulus than ufual. This increafe of aclion con- ftitutes the hot fit of fever, which is attended with various increafed fecretions, with great concomitant heat, and general uneaiinefs. The uneafinefs attend- ing this hot paroxvfm of fever, or fit of exertion^ is very different from that, which attends the pre- vious cold fit, or fit of quiefcence, and is frequent- ly the caufe of inflammation, as in pleurify, which is treated of in the next fedtion. A iimilar effect occurs after the quiefcence of our organs of fenfe ; thofe which are not fubject to per- petual aclion^ as the tafte and fmell, are lefs liable to an exuberant accumulation of fenforial power after their having for a time been ina&ive ; but the eye, which is in perpetual action during the day, becomes dazzled, and liable to inflammation after a temporary quiefcence. Where the previous quiefcence has been owing to a defect of fenforial power, and not to a defect of ftimulus, as in the irritative fever with weak pulfe, a Iimilar increafe of adlivity of the arterial fyftenx fucceeds, either from the ufual ftimulus of the blood, or from a ftimulus lefs than ufual ; but as there is in general in thefe cafes of fever with weak pulfe a deficiency of the quantity of the blood, the pulfe in the hot fit is weaker than in health, though it is ftronger than in the cold fit, as explained in No. 2. of this fection. But at the fame time in thofe fevers, where the defect of irritation is owing to the de- fect of the quantity of fenforial power, as well as to the defect of ftimulus, another circumftance oc- curs ; which conlifts in the partial diftribution of it, Gg z as 446 DISEASES OF IRRITATION. SECT XXXII. 10. as appears in partial flufhings, as of the face or bofom, while the extremities are cold; and in the increafe of particular fccretions, as of bile, faliva, infenfible perfpiration, with great heat of the fkin, or with partial fweats,or diarrhoea. There are alfo many uneafy fenfations attending thefe increafed actions, which, like thofe belonging to the hot fit of fever with (hong pulfe, are fre- quently followed by inflammation, as in fcarlet fe- ver ; which inflammation is neverthelefs accompa- , nied with a pulfe weaker, though quicker, than the pulfe during the remiflion or intermiflion of the pa- roxyfms, though flronger than that of the previous cold fit. From hence I conclude, that both the cold and hot fits of fever are neceflary confequences of the perpetual and inceflant action of the arterial and glandular fyftem fince thofe mufcular fibres, and thofe organs of fenfe, which are moft frequently exerted, become neceflarily moft affected both with defect and accumulation of fenforiai power: and that hence fcwr-fts are not an effort of nature to relieve herfelf, and that therefore they mould always be prevented or diminifhed as much as poflible, by any means which decreafe the general or partial vafcular acti- ons, when they are greater, or by increafing them when they are lefs than in health, as defcribed in Sed. XII. 6. i. Thus have I endeavoured to explain, and I hope to the farisfaction of the candid and patient reader, the principal fymptoms or circumftances of fever without the introduction of the fupernatural power of fpafm. To the arguments in favour or' the doc* trine of fpafm it may be fufficient to reply, that in the evolution of medical as well as of dramatic ca- taftrophe, Ncc Deftft intcrfit, nifi dignus vindicc nodus incident. HOR. SECT. SECT. XXXIII. i. DISEASES OF SENSATION, 447 SECT. XXXIII. DISEASES OF SENSATION. I. Motions excited by fenfation. Digejlion. Genera- tion. Pleafure of exigence. Hypochondriacifm. z. Pain introduced. Senfiticve fevers of two kinds. 3. Two fenforial powers exerted in fenjitive fevers. Size of the blood. Nervous fevers diflingui/bed from pu- trid ones. The feptic and antifeptic theory. 4. TWQ kinds of delirium. 5. Other animals are lefs liable to delirium, cannot receive our contagious difeafes, and are lefs liable to madnefs. II. I. Senfttive moti- ons generated. 2. Injlammation explained. 3. Its remote caufesfrom excefs of irritation, or of irrita- bility, not from thofe pains which are owing to defect of irritation. New vejjiels produced, and much heat* 4. Purulent matter fecreted. 5. Contagion explained. 6. Received but once. 7. If common matter be con- tagious ? 8. Why feme contagions are received but once. 9. Why others may be received frequently. Con- tagions of f mall-pox and meafles do not acJ at the fame times. Two cafes of fuch patients. 10. The blood from patients in the fmall-pox will not infecl others. Cafes of children thus inoculated. The va- rious contagion is not received into the blood. It acls by fenfitive affbciation between thejiomach and Jkin. III. i. Absorption of f olid s and fluids, z. Art of healing ulcers. 3. Mortif cation attended with lefs pain in weak people. I. i. AS many motions of the body are excited and continued by irritations, fo others require, either conjundly 44$ DISEASES OF SENSATION. SECT. XXXIII. t. conjundly with thefe, or feparately, the pleafurable or painful fenfations, for the purpofe of producing them with due energy. Amonglt ihefe the bufinefs of digeition fupplies us with an inftance ; if the food, which we Swallow, is not attended with agree- ably fenfation, it digefts lefs perfectly ; and if very difagreeable fenfation accompanies it, fuch as a nau- feous idea, or very difguflful tafte, the digeflion be- comes impeded ; or retrograde motions of the fto- ipach and cefophagus fucceed, and the food is, The bufinefs of generation depends fo much on agreeable fenfation, that, where the object is diC guit-ul, neither voluntary exertion nor irritation can effedi the purpofe ; which is alfo liable to be inter- rupted by the pain of fear or bafhfijlnefs. Befides the pleasure, which attends the irritations produced by the objeds pf luil and hunger, there feems to be a fum of pleafurable affection accompa- nying the various fecretions of the numerous glands, which conftitute the pleafure of life, in contradif- tincuon to the tsedjum vitse. This quantity or fum of pleafurable affe&ion feems to contribute to the due or energetic performance of the whole move- |ible tyftem, as well that of the heart and arteries, as of digeflion and of abforption ; fince without fhe due quantity of pleafurable fenfation, flatulen- cy and hypochondriacifrn affedt the inteftines, and a languor feizes the arterial pt^lfations and fecreti- ons ; as occurs in great and continued anxiety of the mind. 2. Betides the febrile motions occafioned by irrita- tion, defcribed in Seel:. XXXII. and termed irritative fever, it frequently happens that pain is excited by the violence of the fibrous contractions ; and other new motions are then fuperadded, in confequence, of fenfation, which we (hall term febris fenfitiva, or ienfitive fever* It mull be obferved, that moil it"- ritative SEcr.XXXlII. i. DISEASES OF SENSATION. 449 ritative fevers begin with a decreafed exertion of irritation, owing to delea 01 ftimulus ; but that on the contrary the feniitivc fevers, or inflammations, generally begin with the iucreafed exertion of fen- fation, as mentioned in Sect. XXXI. on tempera- ments : for though the cold fit, \vhich introduces inflammation, commences with decreafed irritation, yet the inflammation itfelf commences in the hot lit during the increafe of fenfation. Thus a com- mon puftule, or phlegmon, in a part of little fen- fibility does not excite an inflammatory fever ; but if the ftomach, inteftines, or the tender fubftance beneath the nails, be injured, great fenfation is pro- duced, and the whole fyftem is thrown into that kind of exertion, which conftitutes inflammation. Thefe fenfitive fevers, like the irritative ones, re- folve themfelves into thofe with arterial ftrength, and thofe with arterial debility, that is, with excefs or defect of fenforial power ; thefe may be termed the febris fenfitiva pulfu forti, fenfitive fever with ftrong pulfe, which is the fynocha, or inflammatory fever ; and the febris fenfitiva pulfu debili, fenfitive fever with weak pulfe, which is the typhus gravior, or putrid fever of fome writers. 3. The inflammatory fevers, which are here term- ed fenfitive fevers with flrong pulfe, arc generally attended with fome topical inflammation, as pleu- rify, peripneumony, or rheumatifm, which diftin- guifhes them from irritative fevers with ftrong pulfe. The pulfe is ftrong, quick, and full ; for in this fever there is great irritation, as well as great fenfation, employed in moving the arterial fyftem. The fize, or coagulable lymph, which appears on the blood, is probably an increased fecretion from the inflamed internal lining of the whole arterial fyftem, the thin- ner part being taken away by the increafed abforp- of ^he inflamed lymphatics. The DISEASES OF SENSATION. SECT. XXXIII. t. The fenfitive fevers with weak pulfe, which are termed putrid or malignant fevers, are diftinguifhed from irritative fevers with weak pulfe, called ner- vous fe'/ers, defcribed in the laft fedion, as the former confift of inflammation joined with debility, and the latter" of debility alone. Hence there is greater heat and more florid colour of the fkin in the former, with petechias, or purple fpots, and aph- thae, or floughs in the throat, and generally with prev o contagion. \Vhen animal matter dies, as a flough in the throat, or the mortified part of a carbuncle, if it be kept moifl and warm, as during its adhefion to a living body, it will foon putrify. This, and the origin of contagion from putrid animal fubftances, feem to have given rife to the feptic and antifeptic theory of thefe fevers. The matter in puftules and ulcers is thus liable to become putrid, and to produce microfcopic animal- cula ; the urine, if too long retained, may alfo gain a putrefcent fmell, as well as the alvine feces \ but fonie writers have gone fo far as to believe, that the blood itfelf in thefe fevers has fmelt putrid, when drawn from the arm of the patient : but this feems not well founded ; fince a fmgle particle of putrid matter taken into the blood can produce fever, how can we conceive that the whole mafs could continue a minute in a putrid ftate without deftroying life ? Add to this, that putrid animal fubftances give up air, as in gangrenes ; and that hence if the blood was putrid, air fhould be given out, which in the blood-vefiels is known to occafion immediate death. In thefe fenfitive fevers with ftrong pulfe (or in- flammations) there are two fenforial faculties con- cerned in producing the difeafe, viz. irritation and fenfation ; and hence, as their combined adion is more violent, the general quantity of fenfoiial pow- er becomes further exhaufted during the exacerba- tion, SKCT. XXXIII. i. DISEASES OF SENSATION. 541 tion, and the fyftem more rapidly weakened than in irritative, fever with ftrong pulfe ; where the fpiric of animation is weakened by but one mode ot" us exertion : fo that this febris feniitiva pulfu forti (or inflammatory fever,) may be couiideied as the febris irritativa pulfu forti, with the addition of inflamma- tion ; and the febris fenfitiva pulfu debili (or malig- nant fever) may be confidered as the febris irritativa pulfu debili (or nervous fever;, with the addition of inflammation. 4. In thefe putrid or malignant fevers a deficiency of irritability accompanies the increafe of fenfibi- lity ; and by this waile of fenforial power by the excefs of fenfation, which was already too fmall, arifes the delirium and ilupor which fo perpetually attend thefe inflammatory fevers with arterial debi- lity. In thefe cafes the voluntary power fir ft ceafes to aft from deficiency of fenforial fpirit ; and the ftimuli from external bodies have no effect on the exhaufted fenforial power, and a delirium like a dream is the confequence. At length the internal ftimuli ceafe to excite fufficient irritation, and the fecretions are either not produced at all, pr too par- fimonious in quantity. Amongft thefe the fecretion of the brain, or production of the fenforial power, becomes deficient, till at laft all fenforial power ceafes, except what is juft neceflary to. perform the vital motions, and a f.upor fucceeds ; which is thus owing to the fame caufe as the preceding delirium exerted in a greater degree. This kind of delirium is owing to a fufpenfion of volition, and to the difobedience of the fenfes to. ex- ternal ftimuli, and is always occafio.ned by great debility, or paucity of fenforial power ; it is, there- fore a bad fign at the end of inflammatory fevers, which had previous arterial firength, as rheumatifm, or pleurify, as it (hews the prelence of great ex- hauftion of fenforial power in 3 fyftem, which hav? ing DISEASES OF SENSATION. SECT. XXXIII. i. ing lately been expofed to great excitement, is not fo liable to be ftimulated into its healthy a&ion, either by additional itimulus of food and medicines, or by the accumulation of fenforial power during its prefent torpor. In inflammatory fevers with de- bility, as thofe termed putrid fevers, delirium is fometimes, as well as flupor, rather a favourable fign ; as lefs fenforial power is wafted during its continuance (fee Clafs II. i. 6.8.), and the conititu- tion not having been previoufly expofed to excefs of Simulation, is more liable to be excited after previous quiefcence. When the fum of general pleafurable fenfation becomes too great, another kind of delirium fuper- venes, and the ideas thus excited are miitaken for the irritations of external objedls : fuch a delirium is produced for a time by intoxicating drugs, as fermented liquors, or opium; a permanent delirium of this kind is fometimes induced by the pleafures of inordinate vanity, or by the enthufiaflic hopes of heaven. In thefe cafes the power of volition is incapable of exertion, and in a great degree the external fenfes become incapable of perceiving their adapted ftimuli, becaufe the whole fenforial power is employed or expended on the ideas excited by pleasurable fenfation. This kind of delirium is diftinguifhed from that which attends the fevers above mentioned from its not being accompanied with general debility, but fimply with excefs of pleafurabie fenfation ; and is there- fore in forne meafure allied to madnsfs or to reve- rie; it differs from the delirium of dreams, as in this the power of volition is not totally fufpendid, nor are the fenfes precluded from external ftimula- tion ; there is therefore a degree of confiftency, in this kind of delirium, and a degree of attention to external objects, neither of which exifl in the deli- rium of fevers or in dreams. SECT. XXXIII. a. DISEASES OF SEMSATION. 453 5. It would appear, that the vafcular fyftem of other animals are lefs liable to be put into action by their general fum of pleafurable or painfui fen- fation ; and that the trains of their ideas, and the mufcular motions uiually aflbciated with them, are lefs powerfully conneded than in the human fyitem. For other animals neither weep, nor fmile, nor Jaugh ; and are hence feldom fubjeft to delirium,, as treated of in Sed}. XVI. on InftincL Now as pur epidemic and contagions djfeafes are probably produced by difagreeable feafatiou, and not fimply by irritation ; there appears a reafon, why brute animals are lefs liable to epidemic or contagious difeafes; and fecondiy, why none of our contagions, as the fmall-pox or meafles, can be communicated to them, though oae of theirs, viz. the hydropho- bia, as well as many of their poifons, as thofe of foakes and of infe&s, cornmunjcate tbeir Deleterious or painful effedls to mankind- Where the quantity of general painful fenfation is too great in the fyftem, inordinate voluntary ex- ertions are produced either of pur ideas, as in me- lancholy and madnefs, or of our mufcles, as iu convulfion. From thefe maladies alfo brute animals are much more exempt than mankind, owing to their greater inaptitude to voluntary exertion, as mentioned in Seel. XVI. on Inftincl. IL i. When any moving organ is excited into fuch violent motions, that a quantity of pleafurable pr painful fenfation is produced, it frequently hap- pens (but not always) that new motions of the af- fefted organ are generated in confequence of the pain or pleafure, which are termed inflammation. Thefe new motions are of a peculiar kind, tend- ing to diflend the old, and to produce new fibres, and thence to elongate the ftraight mufcles, which ferve locomotion, and to form new veflels at the extremities or fides of the vafcular mufcles. 2. Thus 4S4 DISEASES OF SENSATION. SECT. XXXIII. a, 2. Thus the pleafurable fenfations produce an enlargement of the nipples of nurfes, of the papillse of the tongue, of the penis, and probably produce the growth of the body from its embryon ftate to its maturity ; whilft the new motions in confequence of painful fenfation, with the growth of the fibres or veflels, which they occafion, are termed inflamma- tion. Hence when the flraight mufcles are inflamed, part of their tendons at each extremity gain new life and fenfibility, and thus the mufcle is for a time elongated ; and inflamed bones become foft, vafcu- lar, and fenfible. Thus new veflels (hoot over the cornea of inflamed eyes, and into fchirrhous tu- mours, when they become inflamed ; and hence all inflamed parts grow together by intermixture, and inofculation of the new and old veflels. The heat is occaiioned from the increafed fecre- tions either of mucus, or of the fibres, which pro- duce or elongate the veflels. The red colour is owing to the pellucidity of the newly formed veflels, and as the arterial parts of them are probably form- ed before their correfpondent venous parts. 3* Thefe new motions are excited either from the increafed quantity of fenfation in confequence of greater fibrous contractions, or from increafed feniibility, that is, from the increafed quantity of fenforial power in the moving organ. Hence they are induced by great external ftimuli, as by wounds, broken bones, and by acrid or infectious materials, or by common ilimulion thofe organs, which have been fome time quiefcein ; as the ufual light of the day inflames the eyes of thofe, who have been confined in dungeons ; and the wTarrnth of a com- mon fire inflames thofe, who have been previoufly expofed to much cold. But thefe new motions are never generated by that pain, which arifes from defect of ftirnulus, as from SECT.XXXIIT.2. DISEASES OF SENSATION. 455 from hunger, third, cold, or inanition, with all thofe pains which are termed nervous. Where thefe pains exift, the motions of the affected part are leilened ; and if inflammation fucceeds, it is in fome diiiant parts ; as coughs are caufed by coldnefs and moifture being long-applied to the feet ; or it is in confequence of the renewal of the flimulus, as of heat or food, which excites our organs into ftronger acti- on aftet their temporary quiefcence ; as kibed heels after walking in fnow. 4. But when thefe new motions of the vafculaf mufcles are exerted with greater violence, and thefe veffels are either elongated too much or too haftily, a new material is fecreted from their extremities, which is of various kinds according to the pecu- liar animal motions of this new kind of gland, which fecre'es it ; fuch is the pus laudabile or common matter, the variolous matter, venereal matter, ca* tarrhous matter, and many others. 5. Thefe matters are the product of an animal procefs ; they are fecreted or produced from the blood by certain difeafed motions of the extremities of the blood-vefiels, and are on that account all of them contagious ; for if a portion of any of thefe matters is tranfmitted into the circulation, or perhaps only inferted into the ikin, or beneath the cuticle of an healthy perfon, its flimulus in a certain time produces the fame kind of morbid mo- tions, by which itfelf was produced ; and hence a iimilar kind is generated. See Seel. XXXIX. 6. I. 6. It is remarkable, that many of thefe contagi- ous matters are capable of producing a fimilar dif- eafe but once ; as the final 1-pox and meafles ; and I fuppofe this is true of all thofe contagious dif- eafes, which are fpontaneoufly cured by nature in a certain time ; for if the body was capable of re- ceiving the difeafe a fecond time, the patient muft perpetually infed himfelf by the very matter, which he 456 DISEASES OF SENSATION. SE£T. XXXIII. 2, he has himfelf produced, and is lodged about him ; and hence he could never become free from the difeafe. Something fimilar to this is feen in the fe> condary fever of the confluent fmall-pox ; there is a great ablbrption of variolous matter, a very minute part of which would give the genuine fmall-pox to another peribnj but here it only Simulates the fyf- tem into common fever ; like that which common pus, or any other acrid material might occalion. 7. In the pulmonary confumption, where com- mon matter is daily abforbed, an irritative fever only, without new inflammation, is generally pro- duced ; which is terminated like other irritative fevers by fweats or loofe (tools. Hence it does not appear, that this abforbed matter always ads as a contagious material producing frefh inflammation or new abfcefles. Though there is reafon to believe* that the firft time any common matter is abforbed, it has this eifecl, but not the fecond time, like the variolous matter above mentioned. This accounts for the opinion, that the pulmo- nary confumption is fometirnes infectious, which opinion was held by the ancients, and continues in Italy at prefent ; and I have myfelf feen three or four inftances, where a hulbaud and wife, who have flept together, and have thus much received each other's breath, who have infected each other, and both died in confequence of the original taint or* only one of them. This alfo accounts for the ab- fcefles in various parts of the body, that are fome* times produced after the inoculated fmall-pox is terminated; for this fecond abforp'ion of variolous matter afts like common matter, and produces only irritative fever in thofe children, whofe conftituti- ons have already experienced the abforption of com- mon matter ; and inflammation with a tendency to produce new abfcefles in thofe, whofe conftitutions have SECT. XXXIII. 2. DISEASES OF SENSATION. 457 ' have not experienced the abforptions of coramoa matter. It is probable, that more certain proofs might have been found to fhew, that common matter is infectious the fir ft nine it is abfnrbed, tending to produce fimilar abfceffes, but not the fecond time of its abforption, if this fubject had been attended to. 8. 'I hefe contagious difeafes are very numerous, as the plague, fmall-pox, chicken-pox, meafles, fcar- let-fever, pemphigus, catarrh, chincough, venereal difeafe, itch, trichoma, tinea. The infectious ma- terial does not feem to be diflblved by the air, but only mixed with it perhaps in fine powder, which foon fubiides ; fince many of thefe contagions can only be received by actual contact, and others of them only at fmall diftances from the infected per- fon, as is evident from many perfons having been near patients of the fmall-pox without acquiring the difeafe. The reafon why many of thefe- difeafes are re- ceived but once, and others repeatedly, is not well underflood ; it appears to me, that the conftitution becomes fo accuftomed to the iiimuii of thefe in- fectious materials, by having once experienced them, that though irritative motions, as hectic fevers, may again be produced by them, yet no fenfation, and in confequence no general inflammation fucceeds ; as difagreeable fmells or taftes by habits ceafe to be perceived ; they continue indeed to excite irritative ideas on the organs of fenfe, but thefe are not fuc- ceeded by fenfation. There are rn.my irritative motions, which were at firft fucceecled by fenfation, but which by fre- quent repetition ceafe to excite fenfarion, as explain- ed in Sect. XX. on Vertigo. And, that this circum- ftance exifls in refpect to infectious matter appears from a known fact ; that nurfes, who have had the fmall-pox, are liable to experience fmall ulcers on their 458 DISEASES OF SENSATION. SECT. XXXIII. 2. their arms by the contact of variolous matter in lifting their patients ; and that when patients, who have formerly had the fmali pox have been inocu- lated in the arm, a phlegmon, or inflamed fore, has fucceeded, but no fubfequent fever. Which (hews, that the contagious matter of the fmall-pox has not loft its power of ilimulating the part it is applied to, but that the general fyftem is not affeded in confequence. See Sect. XII. 7. 6. XIX. 10. 9. From the accounts of the plague, virulent ca- tarrh, and putrid dyfentery, it feems uncertain, whether thefe difeafes are experienced more than once ; but the venereal difeafe and itch are doubtlefs repeatedly infedlious \ and as thefe difeafes are never cured fpontaneoully, but require medicines, which act without apparent operation, fome have fufpecl:- cd, that the contagious material produces fimilar matter rather by a chemical change of the fluids, than by an animal procefs ; and that the fpecific me- dicines deftroy their virus by chemically combining with it. This opinion is fuccefsfully combated by Mr. Hunter, in his Treatife on Venereal Difeafe, Part I. c. i. But this opinion wants the fupport of analogy,, as there is no known procefs in animal bodies, which is purely chemical, not even digeftion ; nor can any of thefe matters be produced by chemical procefles. Add to this, that it is probable, that the infects, obferved in the puftules of the itch, and in the (tools ot dyfenteric patients, are the confequences, and not the caufes of thefe difeafes. And that the fpe- cific medicines, which cure the itch and lues vene- rea, as brim (lone arid mercury, adt only by increaf- ing the abforption of the matter in the ulcufcles of thofe difeafes, and thence clifpofmg them to heal'; which would other wife continue to fpread. Why the venereal difeafe, and itch, and tenia, or fcald head, are repeatedly contagious, while thofe contagions S*CT. XXXIII a. DISEASES OF SENSATION. 459 contagions attended with fever can be received but once, feems to depend on their being rather local difeafes than univerfal ones, and are hence not at- tended with fever, except the purulent fever in their laft llages, when the patient is deftroyed by them. On this account the whole of the fyftem does not become habituated to thefe morbid adions, fo as to ceafe to be affected with fenfation by a repetition of the contagion. Thus the contagious matter of the Venereal difeafe, and of the tenia, affects the lym- phatic glands, as the inguinal glands, and thofe about the roots of the hair and neck, where it is ar retted, but does not feem to affect the blood- reffels, fmce no fever enfues. Hence it would appear, that thefe kinds of con- tagion are propagated not by means of the circula- tion, but by fympathy of diftant parts with each other ; fince if a diftant part, as the palate, fhould be excited by fenfitive affociation into the fame kind of motions, as the parts originally affected by the contact of infectious matter ; that dif- tant part will produce the fame kind of infectious matter ; for every fecretion from the blood is formed from it by the peculiar motions of the fine ex- tremities of the gland, which fecretes it ; the vari- ous fecreted fluids, as the biles faliva, gaftric juice, Hot previouily exifting, as fuch, in the blood- vef- fels. And this peculiar fympathy between the genitals the throat, owing to fenfitive affociation, ap- pears not only in the production of venereal ulcers in the throat, but in variety of other inttances, as in the mumps, in the hydrophobia, fome coughs, ftrangulation, the production of the beard, change of voice at puberty. Which are further defcribed inClafsIV. i. 2.7. To evince that the production of fuch large quan- tities of contagious matter, as are Teen in fome H h variolous 460 DISEASES OF SENSATION. SKCT.XXXlTf 2. variolous patients, fo as to cover the whole fkin almoft with puflules, does not arife from any che- mical fermentation in the blood, but that it i» owing to morbid motions of the fine extremities of the capillaries, or glands, whether thefe be rup- tured or not, appears from the quantity of this matter always cor ref ponding with the quantity of the fever ; that is, with the violent exertions of thofe glands and capillaries, which are the terminations of the arterial fyftem. The truth of this theory is evinced further by a circumftance obferved by Mr. J. Hunter, in his Treatife on Venereal Difeafe ; that in a patient, who was inoculated for the fmall-pox, and who appear- ed afterwards to have been previoufly infeded with the meafles, the progrefs of the fmall-pox was de- layed till the meafles had run their courfe, and that then the fmall-pox went through its ufual periods. Two fimilar cafes fell under m-y care, which I (hall here relate, as it confirms that of Mr. Hunter, and contributes to illuftrate this part of the theory of contagious difeafes. I have tranfcribed the par- ticulars from a letter of Mr. Lightwood of Yoxal* the furgeon who daily attended them, and at my requeft, after I had feen them, kept a kind of jour- nal of their eafes. Mifs H. and Mifs L. two fitters, the one about four and the other about three years old,, were ino- culated Feb. 7, 1791- On the loth there was a rednefs on both arras difcernible by a glafs. On the i ith their arms were fo much inflamed as to leave no doubt of the infection having taken place. On the 1 2th lefs appearance of inflammation on their arms. In the evening Mifs L. had an erup- tion, which refembled the meafles. On the I3th the eruption on Mifs L. was very full on the face and breaii, like the meafles, with confiderable fever. It was now known, that the meafles were in a farm houfe SECT. XXXIII. 2. DISEASES OF SENSATION, 461 houfe in the neighbourhood. Mrfs H.'s arm lefs in- flamed than yellerday. On the I4th Mifs L.'s fever great, and the eruption univerfal. The arm appears to be healed. Mifs H.'s arm fomewhat redder. They were now put into fcparate rooms. On the i5th Mifs L.'s arms as yefteiday. Eruption continues. Mifs H.'s arms have varied but little i6th, the eruptions on Mifs L. are dying away, her fever gone. Begins to have a little rednefs in one arm at the place of inoculation. Mifs H.'s arms get redder, but fhe has no appearance of complaint. 2othy Mifs L.'s arms have advanced flowly till this day, and now a few puftules appear* Mifs H.'s arm has made little progrefs from the i6th to this day, and fiow {he has fome fever. 2ift5 Mifs L. as yefter- day. Mifs H. has much inflammation, and an in- Creafe of the red circle on one arm to the fize of half a crown, and had much fever at night, with fetid breath. 22d, Mifs L.'s puftules continue ad- vancing. Mifs H.'s inflammation of her arm and red circle increafes. A few red fpots appear in dif- ferent parts with fome degree of fever this morningv 23d, Mifs L. has a larger crop of puftules. Mils H. has fmall puftules and great inflammation of her arms, with but one puftule likely to fuppurate. Af- ter this day they gradually got well, and the puftules difappeared. In one of thefe cafes the meafles went through their common courfe with milder fymptoms thaa ufual, and in the other the meafly contagion feemed juft fufficient to (top the progrefs of variolous con- tagion, but without itfelf throwing the conflitution into any diforder. At the fame time both the meafles and fmall-pox feem to have been rendered milder. Does not this give an idea, that if they were both inoculated at the fame time, neither of them might affect the patient ? H h 2 From 462 DISEASES OF SENSATION. SECT. XXXIII. a. From thefe cafes I contend, that the contagious matter of thefe difeafes does nor affect the confuta- tion by a fermentation, or chemical change of the blood, becaufe then they muft have proceeded toge- ther, and have produced a third fomething, not exactly iimilar to either of them : but that they produce new motions of the cutaneous terminations of the blood- vefie Is, which for a time proceed daily •with increafing activity, like forae paroxyfms of fe- ver, till they at length fecrete or form a fimilar poifon by thefe unnatural actions* Now as in the meafles one kind of unnatural mo- tion takes place, and in the fmaTl-pox another kind, it is eafy to conceive, that thefe different kinds of morbid motions cannot exift together ; and there- fore, that that which has firft begun will continue till the fyftem becomes habituated to the ftimulus which occafions- it, and has ceafed to be thrown into aclion by it; and then the other kind of ftimu- lus will in its turn produce fever, and new kinds of motions peculiar to itfelf. 10. On further considering the aclion of conta- gious matter, fince the former part of this work was fent to the prefs; where I have aliened, in Sect., XXII. 4. 3. that it is probable, that the variolous matter is diffufed through the blood; I prevailed on: my friend Mr. Power, furgeon at Bofworth in Lei- cefterfhire to tryr whether the fmall-pox eould be inoculated by ufing the blood of a variolous pati- ent inftead of the matter from the puftules ; as I thought fuch an experiment^ might throw fome light at lead on this interesting fubject. The following, is an extract from his letter ;— **. March 1 1 r 1793- I inoculated two children,, who had not had the fmall-pox, with blood ; which was taken from a patient on the fecond day after the eruption commenced, and before it was completed* And at the fame time I inoculated myfelf with blood SECT. XXXIII. s. DISEASES OF SENSATION. 463 blood from the fame perfon, in order to compare the appearances, which might arife in a perfon lia- ble to receive the infection, and in one not liable to receive it. On the fame day I inoculated four other children liable to receive the infection with blood taken from another perfon on the fourth day after the commencement of the eruption. The patients from whom the blood was taken had the difeafe mildly, but had the moft puflules of any I could felecl from twenty inoculated patients ; and as much of the blood was infmuated under the cuticle as I could introduce by elevating the (kin without draw- ing blood ; and three or four fuch punctures were made in each of their arms, and the blood was ufed in its fluid ftate. " As the appearances in all thefe patients, as well as in myfelf, were fimilar, I fhall only mention them in general terms. March 13. A flight fubcu- ticular difcoloration, with rather a livid appearance, without forenefs or pain, was vifible in them all, as well as in my own hand. 15. The difcolo ration, fomewhat lefs, without pain or forenefs. Some pa- tients inoculated on the fame day with vanolous matter have conliderable inflammation. 17. The difcoloration is quite gone in them all, and from my own hand, a dry mark only remaining. And they were all inoculated on the iSth, with variolous mat- ter, which produced the difeafe in them all." Mr. Power afterwards obferves, that, as the pati- ents from whom the blood was taken had the dif- eafe mildly, it may be fuppofed, that though the contagious matter might be mixed with the blood, it might dill be in too dilute a (late to convey the infection ; but adds at the fame time, that he has dilute:! -recent matter with at leaf! five times its quantity of water, and which has flill given the in- feclion ; though he has fometimes diluted it fo far as to fail. The 464 DISEASES OF SENSATION. SECT. XXXIII, ». The following experiments were inflituted at my requeft by my friend Mr. Hadley, furgeon in Derby, to afcertain whether the blood of a perfon in the fmall-pox be capable of communicating the difeafe. "Experiment lit. Oclober i8th, 1793. I took fome blood from a vein in the arm of a perfon who had the fmall-pox, on the fecond day of the eruption, and introduced* a fmall quantity of it immediately with the point of a lancet between the fcarf and true fkin of the right arm of a boy nine years old in two or three different places ; the other arm was inoculated with variolous matter at the fame time. ** J9th. The puuv^ured parts of the right arm were furrounded with fome degree of fubcuticular inflammation, soth. The inflammation more con- iiderable, with a flight degree of itching, but no pain upon preflure. 21 ft. Upon examining the arm this day with a lens I found the inflammation lefs extenfive, and the rednefs changing to a deep yel- low or orange-colour. 22d. Inflammation nearly gone. 2jd. Nothing remained, except a flight dif- coloration and a little fcurfy appearance on the pun£lures. At the fame the inflammation of th$ arm inoculated with variolous matter was increafing faft, and he had the difeafe mildly at the ufual time. " Experiment 2d. I inoculated another child at the fame time and in the fame manner, with blood taken on the firft day of the eruption ; but as the appearance and effe&s were fimilar to thofe in the preceding experiment, I (hall not relate them mi* nutely. -^ «' Experiment 3d. October 2pth. Blood was taken from a perfon who had the fmall-pox, on the third day of the eruption, and on the fixth from the commencement of the eruptive fever. I introduced fome of it in its fluid flate into both arms of a boy feven years old. 2ift. There appeared to be fome inflammation. Sacr. XXXIII. a. DISEASES OF SENSATION. 465 inflammation under the cuticle, where the punctures xvere made, 22d. Inflammation more coniiderable. 23d. On this day the inflammation was fomewhat greater, and the cuticle rather, elevated. , when by the painful fenfation a more inordinate activity of the organ is produced, and by this great activity an additional quantity of painful fenfation follows in an increafmg ratio, till the whole of the fenfqrial power, or fpirit of animation, in the part becomes exhaufted, a mor- tification enfues, as in a carbuncle, in inflamma- tions of the bowels, in the extremities of old people, or. in the limbs of thofe who are brought near a fire after having been much benumbed with cold. And SECT. XXXIII. 4- DISEASES OF SENSATION. 471 And fvom hence it appears, why weak people are more fubject to mortification than ftrong ones, and why in weak perfons lefs pain will produce mortifica- tion, namely, becaufe the fenibrial power is fooner exhaufted by any excels of activity* I remember feeing a gentleman who had the preceding day tra- velled twro ftages in a chaife with what he termed a bearable pain in his bowels ; which when I faw him had ceafed rather fuddenly, and without a paf- £age through him ; his pulfe was then weak, though not very quick ; but as nothing Which he fwallowed would continue in bis ftomach many minutes, I con* eluded that the bowel was mortified -r he died on the next day. It is ufual for patients finking under the fmall-pox w7ith mortified puilules, and with purple fpots intermixed, to complain of no pain, but to fay they are pretty well to the laft momeut. IV. When the motions of any part of the fyftem, in confequence of previous torpor, are performed with more energy than in the irritative fevers, a difagreeable lenfation is produced, and new a&ions of fome part of the fyftem commence in confequence of this fenfation conjointly w ith the irritation : which motions conftitute inflammation. If the fever be attended with a flrong pulfe, as in pkurify, or rheu- rnatifm, it is termed fynocha fenfitiva, or fenfuive fever with ftrong pulfe ; which is ufually termed in- flammatory fever. If it be attended with weak pulfe, it is termed typhus feniitivus, or fenfitive. fever with weak pulfe, or typhus gravior, or putrid ma- lignant fever. The fynocha fenfitiva, or fenfitive fever with ftrong pulfe, is generally attended with fome topical inflammation, as in peripneumony, hepatitis, and is- accompanied DISEASES OF SENSATION. SECT. XXXIII. 4, accompanied with much coagulable lymph, or fize ; which rifes to the furface of the blood, when taken into a bafon, as it cools ; and which is believed to be the increafed mucous fecretion from the coats of the arteries, infpiffated hy a greater abforption of its aqueous and faline parts, and perhaps changed by its delay in the circulation. The typhus fenfuivus, or fenfitive fever with weak pulfe, is frequently attended with delirium, which is caufed by the deficiency of the quantity of fenfo«- rial power, and with variety of cutaneous erup* tions. Inflammation is caufed by the pains occafioned by excefs of aftion, and not by thofe pains which are occafioned by defect of action, Thefe morbid actions, which are thus produced by two fenforial powers, viz. by irritation and fenfation, fecrete new living fibres, which elongate the old veflels, or form new ones, and at the fame time much heat is evolved from thefe combinations. By the rupture of thefe velfels, or by a new conftruclion of their apertures, purulent matters are fecreted of various kinds ; which are infectious the firft time they are applied to the fkin beneath the cuticle, or fwallowed with the fa- liva into the ftomach. This conragion acts not by its being abforbed into the circulation, but by the fympathies, or aflbciated actions, between the part firft Simulated by the contagious mattsr and the other parts of the fyftem. Thus in the natural fmall-pox the contagion is fwallowed with the faliva, and by its flimulus inflames the ftomach ^ this vari- oloos inflammation of the ftomach increafes every day, like the circle round the pundlure of an ino- culated arm, till it becomes great enough to difordef the circles of irritative and fenfitive motions, and thus produces fever-fits, with ficknefs and vomiting. Laftly, after the cold paroxyfm, or fit of torpor, of the ftomach has increafed for two or three fuccef- live SHOT. XXXIII. 4. DISEASES OF SENSATION. 473 five days, an inflammation of the fkin commences in points ; which generally firft appear upon the face, as the aflbciated addons between the fkin of the face and that of the ftomach have been more frequently exerted together than thofe of any other parts of the external furface. Contagious matters, as thofe of the meafles and fmall-pox, do not ad upon the fyftem at the fame time ; but the progrefs of that which was laft re- ceived is delayed, till the a&ion of the former in- fedion ceafes. All kinds of matter, even that from common ulcers, are probably contagious the firfl time they are inferted beneath the cuticle or fwal- lowed into the ftomach ; that is, as they were form- ed by certain morbid actions of the extremities of the veflels, they have the power to excite fimilar morbid actions in the extremities of other veflels, to which they are applied ; and thefe by fympathy, or affociafions of motion, excite fimilar morbid ac- tions in diftant parts of the fyflem, without entering the circulation -9 and hence the blood of a patient in the {mall-pox will not give that difeafeby inocu- lation to others. When the new fibres or veflels become again ab- forbed into the circulation, the inflammation ceafes ; which is promoted, after fufficient evacuations, by external flimuiants and bandages: but where the aclion of the veflels is very great, a mortification of the part is liable to enfue, owing to the exhaufiioiji of fenforial power ; which however occurs in weak people without much pain., and without very violent previous inflammation ; and, like partial paralyfis, may be efteemed one mode of natural death of old people, a part dying before the whole. SECT. 474 DISEASES OF VOLITION. SECT. XXXIV. SECT, xxxivi DISEASES OF j. i. Volition defined. Motions termed involuntary are caused by volition* Defires oppofed to each other. Deliberation, 4fs between two hay -cocks. Saliva fwallow'ed again/I Qn£$ defire. Voluntary motions dijlinguijhed from thofe ajjociated with /enfttive mo- tions. 2. Pains from excefs, and from defect of motion* No pain is felt during vehement voluntary exertion ; as in cold Jits of ague, laboitr -pains, Jlran- gury, tenefmus, vomiting, rejllejjnefs in fevers, con- vuljion of a wounded mufcle. 3. Of holding the breath and f creaming in pain ; why fwine and dogj cry out in pain y and not Jheep and horfes. Of grin- ning and biting in pain ; why mad animals bite others, 4. Epileptic convulfions explained, why the jits begin with, quivering of the under jaw, biting the tongue, andfetting the teeth ; why the convuljive motions art alternately relaxed* The phenomenon of laughter1 explained. Why children cannot tickle themf elves. How fome have died from immoderate laughter., 5. Of cataleptic fpafms, of the locked jaw, of painful cramps. 6. Syncope explained. Why no external objecls are perceived in fyncope. 7. Of pal fy and apoplexy from violent exertions. Cafe of Mrs. Scot* From dancing, f eating, fwimming. Cafe of Mr*> Nairn. Why palfies are not always immediately pre- ceded by violent exertions. Palfy and epilepfy from difeafed livers. Why the right arm more frequently paralytic than the left. How paralytic limbs regain their motions. II. . Dif safes of the fenfual motions from SECT. XXXIV. i. DISEASES OF VOLITION. 47* from excefs or defeft of voluntary exertion. I. Mud- nefs. 2. Diftinguifhed from delirium. 3. Why man- kind more liable to infanity than brutes. 4. Sufpicion. Want of Jhame, and of cleanliness. 5. They bear cold, hunger, and fatigue. Charles XII. of Sweden. 6. Pleasurable delirium, and infanity. Child riding on ajiick. Pains of martyrdom not felt. 7. Dropfy. 8. Injlammation cured by infanity. III. I. Pain re- lieved by reverie. Reverie is an exertion of volun- tary and fenfttive motions, z. Cafe of reverie. 3. Lady fuppofed to have two fouls. 4. Methods of relieving fain. I. i. BEFORE we commence this Seftion on Difeafed Voluntary Motions, it may be neceffary to premife, that the word volition is not ufed in this work exactly in its common acceptation. Volition is faid in Seftion V. to bear the fame analogy to defire and averfion, which fenfation does to pleafure and pain. And hence that, when deiire or averfion produces any action of the mufcular fibres, or of the organs of fenfe, they are termed volition ; and the actions produced in confequence are termed vo- luntary actions. Whence it appears, that motions of our mufcles or ideas may be produced in confe- quence of defire or averfion without our having the power to prevent them, and yet thefe motions may be termed voluntary, according to our definition of the word ; though in common language they would be called involuntary. The objects of defire and averfion are generally at a diftance, whereas thofe of pleafure and pain are immediately acUng upon our organs. Hence, befoie defire or averfion are exerted, fo as to caufe any actions, there is generally time for deliberation ; which confifts in difcovering the means to obtain the object of defire, or to avoid the object of aver- fion ; or in examining the good or bad confequences VOL. I. I i which 476 DISEASES OF VOLITION. SECT. XXXIV. i> which may refuh from them. In this cafe it is evident, that we have a power to delay the pro- pofed adion, or to perform it ; and this power of choofmg, whether we (hall aft or not, is in com- mon language expreflfed by the word volition, or will. Whereas in this work the word volition means fimpty the active ftate of the fenforial faculty in pro- ducing mqtion in confequence of defire or averfion : Whether we have the power of reftraining that ac- tion, or not ; that is, whether we exert any actions in confeque^ee of oppofite defires, or averfions,. or not. For if the objects of defire or averfion are pre- fent, there is no neceflity to inveftigate or compare the means of obtaining them, nor do we always de- liberate about their confequences ; that is, no deli- beration neceflarily intervenes, and in confequenee the power of choofing to aft or not is not exerted. It is probable, that this twofold ufe of the word volition in all languages has confounded the meta- phyficians, who have difputed about free will and neceflity. Whereas from the above analyfis it would appear, that during our fleep, we ufe no voluntary exertions at all ; and in our waking hours, that they are the confequenee of defire or averfion. To will is to aft in confequenee of defire ; but to defire means to defire fomething, even if that fomething be only to become free from the pain, which caufes the defire ; for to defire nothing is not to defire ; the word defire, therefore, includes both the adtion and the objedl or motive ; for the objeft and motive of defire are the fame thing. Hence to defire without an object, that is, without a motive, is a folecifm in language. As if one fhould afk, if you could eat without food, or breathe with- out air. From this account of volition it appears, that con- vulfions of the mufcles, as in epileptic fits, may in the tommon fenfc of that word be termed involun- • taryj SECT. XXXIV. i. DISEASES OF VOLITION. 477 tary ; becaufe no deliberation is interpofed between the defire or averfion and the confequent a&ion ^ but in the fenfe of the word, as above defined, they belong to the clafs of voluntary motions, as deli- vered in Vol. II. Clafs III. If this ufe of the word be difcoidant to the ear of the reader, the terra morbid voluntary motions, or motions in confe- quence of averfion, may be fubftituted in its (lead. If a perfon has a delire to be cured of the ague, and has at the fame time an averfion (or contrary defire) to fwallowing an ounce of Peruvian bark; he balances defire againft defire, or averfion againft averfion; and thus he acquires the power of choof- ing, which is the common acceptation of the word willing. But in the cold fit of ague, after having difcovered that the a6l of fhuddering, or exerting the fubcutaneous mufcles, relieves the pain of cold; he immediately exerts this aclof volition, andfhud- ders, as foon as the pain and confequent averfion return, without any deliberation intervening ; yet is this aci, as well as that of fwallowing an ounce of the bark, caufed by volition ; and that even though he endeavours in vain to prevent it by a weaker con- trary volition. This recalls to our mind the ftory of the hungry 'afs between two hay-ftacks, where the two defires are fuppofed fo exactly to counteract each other, that he goes to neither of the flacks, but perifhes by want. Now as two equal and op- pofite defires are thus fuppofed to balance each other, and prevent all action, it follows, that if one of thefe hay-ftacks was fuddenly removed, the afs would irrefiftibly be hurried to the other, which in the common ufe of the word might be called an involuntary a& ; but which, in our acceptation of it, would be clalfed amongft voluntary adlions, as above explained. Hence to deliberate is to compare oppofmg defires or averfions, and that which is the mod intereiling Ii 3 at 47§ DISEASES OF VOLITION. SECT. XXXIV. i. at length prevails, and produces a$ion. Similar to this, where two pains oppofe each other, the ftronger or more interefting one produces adion ; as in pleuiify the pain from fuffocation would pro- duce expanfion of the lungs, but the pain occafi- oned by extending the inflamed membrane, which lines the c heft, oppofes this expanfion, and one or the other alternately prevails. When any one moves his hand quickly near ano- ther perf©n's eyes, the eye-lids inftantly clofe ; this a& in common language is termed involuntary, as we have not time to deliberate or to exert any con* trary defire or averfion, but in this work it would be termed a voluntary aft, becaufe it is caufed by the faculty of volition, and after a few trials the niclitation can be prevented by a contrary or op* pofing volition. The power of oppofing volitions is beft exem- plified in the ftory of Mutius Scaevola, who is faid to have thrufl his hand into the fire before Por- fenna, and to have fuffered it to be confumed for having failed him in his attempt on the life of that prince. Here the averfion for the lofs of fame, or the unfatisfied defire to ferve his country, the two prevalent enthufiafms at that time, were more powerful than the defire of withdrawing his hand, which muft be occafioned by the pain of combufti- on j of thefe oppofing volitions Vicit amor patriac, laudumque immenfa cupi do. If any one is told not to fwallow his faliva for a minute, he foon fwallows it contrary to his will, in the common fenfe of that word ; but this alfo is a voluntary a&ion, as it is performed by the faculty of volition, and is thus to be underllood. When the power of volition is exerted on any of our fenfes, they become more acute, as in our attempts to hear 7 fmall SECT. XXXIV. i. DISEASES OF VOLITION. 479 fmall noifes in the night. As explained in Section XIX. 6. Hence by. our attention to the fauces from our defire not to fwallow our laliva ; the fauces be- come more ferifible ; and the flimulus of the faliva is followed by greater fenfation, and confequent de- fire of fwallowing it. So that the defire or volition in confequence of the increafed fenfation of the fa- liva is more powerful, than the previous defire not to fwallow it. See Vol. II. Deglutitio invita. In the fame manner if a modeft man wifhes not to want to make water, when he is coiifined with ladies in a coach or an aiTembly-room ; that very act of volition induces the circumflance, which he wifhes to avoid, as above explained ; infomuch that I once faw a partial infanity, which might be called a voluntary diabetes, which was occafioned by the fear (and confequent averfion) of not being able to make water at all. It is further neceiTary to obferve here, to prevent any confufion of voluntary, with fenlitive, or affo- ciate motions, that in all the inflances of violent efforts to relieve pain, thofe efforts are at firft vo- luntary exertions ; but after they have been fre- quently repeated for the purpofe of relieving certain pains, they become affociated with thofe pains, and ceafe at thofe times to be fubfervient to the will ; as in coughing, fneezing, and flrangury. Of thefe mo- tions thofe which contribute to remove of diflodge the offending caufe, as the actions of the abdominal mufcles in parturition or in vomiting, though they were originally excited by volition, are in this work termed fenfuive motions ; but thofe actions of the mufcles or organs of fcnfe, which do not contri- bute to remove the offending caufe, as in general convulfions or in madnefs are in this work termed voluntary motions, or motions in confequence of averfion, though in common language they are call- ed involuntary ones. Thofe fenfitive unreftraiuable actions, 480 DISEASES OF VOLITION. SECT. XXXIV. i, actions, which contribute to remove the caufe of pain are uniformly and invariably exerted, as in coughing or fneezing ; but thofe motions which are exerted in confequence of averfion without contri- buting to remove the painful caufe, but only to pre- Srent the fenfation of it, as in epileptic, or catalep- tic fits are not uniformly and invariably exerted, but change from one fet of mufcles to ano- ther, as will be further explained; and may by this criterion alfo'be diflinguifhed from the former. At the lame time thofe motions, which are ex- cited by perpetual ftimulus, or by aflbciation with each other, or immediately by pleafurable or pain- ful fenfation, may properly be termed involuntary motions, as thofe of the heart and arteries ; as the. faculty of volition feldom affects thofe, except when it exifts in unnatural quantity, as in maniacal peo- ple. 2. It was obferved in Section IV. on the Produc- tion of Ideas, that thofe parts of the fyftem, which are ufually termed the organs of fenfe, are liable to be excited into pain by the excels of the ftimu- lus of thofe objects, which are by nature adapted to affeft them ; as of too great light, found, or preflure. But that thefe organs receive no pain from the defect or abfence of thefe ftimuli, as in darknefs or filence. But that our other organs of perception, which have generally been called appe- tites, as of hunger, thirft, want of heat, want of freih air, are liable to be affected with pain by the defect, as well as by the excefs of their appropri- ated ftimulL This excefs or defect of itimulus is however to be confidered only as the remote caufe of the pain, the immediate caufe being the excefs or defe6t of the natural action of the affected part, according to Sect, IV. 5. Hence all the pains of the body may be SECT. XXXIV. i. DISEASES OF VOLITION. 481 foe divided into thofe from excefs of motion, and thofe from deleft of motion ; which diftin&ion is of great importance in the knowledge and the cure of many diieafes. For as the pains from excefs of motion either gradually fublide, or are in general fucceeded by inflammation ; fo thofe from deredt of motion either gradually fubfide, or are in general fucceeded by convulfion, or madnefs. Thefe pains are eaiily diftinguifhable from each other by this circumftance, that the former are atr^n Jed with heat of the pained part, or of the whole body; whereas the latter exifts without increafe of heat in the pained part, and is generally attended with coldnefs of the extremities of the body ; which is the true criterion of what have been called nervous pains. Thus when any acrid material, as muff or lime, falls into the eye, pain and inflammation and heat are produced from the excefs of ftimulus ; but vio- lent hunger, hemicrania, or the clavus hyftericus, are attended with coldnefs of the extremities, and defecl: of circulation. When we are expofed to great cold, the pain we experience from the defi- ciency of heat is attended with a quiefcence of the motions of the vafcular fyftem ; fo that no inflam- mation is produced, but a great defire of heat, and a tremulous motion of the fubcutaneous mufcles, which is properly a convulfion in confequence of this pain from defecl: of the itimulus of heat* It was before mentioned, that as fenfation con- fifts in certain movements of the fenforium, beginr ning at fome of the extremities of it, and propa- gated to the central parts of it ; fo volition con- fids of certain other movements of the fenforium, commencing in the central parts of it, and propa- gated to fome of its extremities. This idea of thefe two great powers of motion in the animal machine is confirmed from obferving, that they ne- ver 48a DISEASES OF VOLITION. SECT. XXXIV. i. ver exift in a great degree or univerfally at the fame time ; for while we ilrongly exert our volun- tary motions, we ceaie to feel the pains or uneafi- nefles, which occafioned us to exert them. Hence during the time of fighting with fids or fwords no pain is felt by the combatants, till they ceafe to exert themfelves. Thus in the beginning of ague fits the painful fenfation of cold is dimi- nifhed, while the patient exerts himfelf in the fhi- vering and gnafhing of his teeth. He then ceafes to exert himfelf, and the pain of cold returns ; and he is thus perpetually induced to reiterate thefe exertions, from which he experiences a temporary relief. The fame occurs in labour-pains, the exer- tion of the parturient woman relieves the violence of the pains for a time, which recur again foon after fhe has ceafed to ufe thofe exertions. The fame is true in many other painful difeafes, as in the ftrangury, tenefmus, and the efforts of vomiting ; all thefe difagreeable fenfations are diminifhed or re- moved for a time by the various exertions they occafioo, and recur alternately with thofe exerti- ons. The reftleffnefs in fome fevers is an almoft perpe- tual exertion of this kind, excited to relieve fome difagreeable fenfations ; the reciprocal oppofite exer- tions of a wounded worm, the alternate emproftho- tonos and opifthotonos of fome fpafmodic difeafes, and the intervals of all convulfions, from whatever caufe, feem to be owing to this circumflauce of the laws of animation ; that great or univerfal exertion cannot exift at the fame time with great or uni- verfal fenfation, though they can exift reciprocally ; which is probably refolvable into the more general law, that the whole ienforial power being expended in one mode of exertion, there is none to fpare for any other. Whence fyncope, or temporary apo- plexy, fucceeds to epileptic convulfions. 3. Hence SECT.XXXtV. i. DISEASES OF VOLITION, 4«5 3. Hence when any violent pain afflicts us, of which we can neither avoid nor remove the caufe, we foon learn to endeavour to alleviate it, by ex- erting fome violent voluntaiy effort, as mentioned above ; and are naturally induced to ufe thofe muf- cles for this purpofe, which have been in the early periods of our lives mod frequently or mod power- fully exerted. Now the firft mufcles, which infants ufe moft frequently, ate thofe oi: refpi ration ; and on this ac- count we gain a habit of hoU iug our breath, at the fame time that we ufe great efforts to exclude it, for this purpofe of alleviaiing unavoidable pain; or we prefs out our breath through a fmall aperture of the larynx, and fcream violently, when the pain is greater than is relievable by the former mode of exertion. Thus children fcream to relieve any pain either of body or mind, as from anger, or fear of being beaten. Hence it is curious to obferve, that thofe animals, who have more frequently exerted their mufcles of refpiration violently, as in talking, barking, or grunting, as children, dogs, hogs, fcream much more, when they are in pain, than thofe other ani- mals, who ufe little or no language in their com- mon modes of life ; as horfes, iheep, and cows. The next moft frequent or mod powerful efforts, which infants are firft tempted to produce, are thofe with the mufcles in biting hard fubitances ; indeed the exertion of thefe mufcles is very powerful in common maftication, as appears from the pain. we receive, if a bit of bone is unexpectedly found amongft our fofter food ; and further ap- pears from their a&ing to fo fo great mechanical difadvantage, particularly when we bite with the incilores, or canine teeth, which are firft formed, and thence are firft ufed to violent exertion. Hence 484 DISEASES OF VOLITION. SECT. XXXIV. K Henee when a perfon is in great pain, the caufe of which he cannot remove, he fets his teeth firmly together, or bites fome fubftance between them with great vehemence, as another mode of violent exer- tion to produce a temporary relief. Thus we have a proverb where no help can be had in pain, «' to grin and abide;" and the tortures of hell are faid to be attended with " gnafhing of teeth." Hence in violent fpafmodic pains I have feen peo- ple bite not only their tongues, but their arms or fingers, or thofe of the attendants, or any object which was near them ; and alfo ftrike, pinch, or tear, others or themfelves, particularly the part of their own body, which is painful at the time. Sol- diers, who die of painful wounds in battle, are faid in Homer to bite the ground. Thus alfo in the bellon, or colica faturnina, tr\e patients are faid to bite their own flefh, and dogs in this difeafe to bite tip the ground they lie upon. It is probable that the great endeavours to bite in mad dogs, and the violence of other mad animals, is owing to the fame caufe. 4. If the efforts of our voluntary motions are exerted with ftill greater energy for the relief of fome difagreeable fenfation, convulfions are produc- ed ; as the various kinds of epilepfy, and in fome hyfteric paroxyfms. In all thefe difeafes a pain or difagreeable fenfation is produced, frequently by worms, or acidity in the bowels, or by a difeafed nerve in the fide, or head, or by the pain of a dif- eafed liver. In fome coaftitutions a more intolerable degree of pain is produced in fome p^rt at a diflance from the caufe by feniitive affociation, as before explain- ed ; thefe pains in fuch conilitutions arife to fo great a degree, that I verily believe no artificial tortures could equal fome, which I have witneffed ; and am confid-ent life would not have long been preferved, unlefs SECT. XXXIV. i. DISEASES OF VOLITION. 4.^5 unlefs they had been foon diminifhed or removed by the univerfal convulfion of the voluntary moti- ons, or by temporary rnadnefs. In fome of the unfortunate patients I have ob- ferved, the pain has rifen to an inexpreflible degree, as above defcribed, before the convulfions have fu- pervened ; and which were preceded by fcreaming, and grinning j in others, a$ in the common epilepfy, the convulfion has immediately fucceeded the com- mencement of the difagreeable fenfations ; and as a ftupor frequently fucceeds the convulficns, they only feemed to remember that a pain at the ftomach preceded the fit, or fome other uneafy feel ; or more frequently retained no memory at all of the immediate caufe of the paroxyfni. But even in this kind of epilepfy, where the patient does not recol- lect any preceding pain, the paroxyfms generally are preceded by a quivering motion of the under jaw, with a biting of the tongue; the teeth afterwards become prefled together with vehemence, and the eyes are then convulfed, before the commencement of the univerfal convulfion ; which are all efforts to relieve pain. The reafon why thefe convulfive motions are al- ternately exerted and remitted, was mentioned above, and in Se&. XII. j. 3. when the exertions are fuch as give a temporary relief to the pain, which ex- cites them, they ceafe for a time, till the pain is again perceived; and then new exertions are pro- duced for its relief. We fee daily examples of this in the loud reiterated laughter of fome people ; the pleafurable fenfation, which excites this laughter, arifes for a time fo high as to change its name and become painful : the convulfive motions of the re- fpiratory mufcles relieve the pain for a time ; we are, however, unwilling to lofe the pleafure, and prefently put a flop to this exertion, and immedi- ately the pleafure recurs, and again as inftantly rifes into 486 DISEASES OF VOLITION. SECT. XXXIV. i. into pain. All of us have felt the pain of immo- derate laughter; children have been tickled into con- vulfions or the whole body ; and others have died in the act of laughing; probably from a paralyhs fucceeding the long continued actions of the mufcles of refpiration. Hence we learn the reafon, why children, who are fo eafily excited to laugh by the tickling of other people's fingers, cannot tickle themfelves into laugh- ter. The exertion of their hands in the endeavour to tickle themfelves prevents the neceffity of any exertion of the refpiratory mufcles to relieve the ex- cefs of pleafarable atfedion. See Sect. XVII. 3. 5. Chryfippus is recorded to have died laughing, when an afs was invited to fup with him. The fame is related of one of the popes, who, when he was ill, faw a tame monkey at his bedfide put on the holy tiara. Hall. Phyf. T. III. p. 306. There are inilances of epilepfy being produced by laughing recorded by Van^Swieten, T. III. 402 and 308. And it is well known, that many people have died inftantaneoufly from the painful excefs of joy, which probably might have been prevented by the pcertions of laughter. Every combination of ideas, which we attend to, pccafions pain or pleafure; thofe which occaiion pleafure, furnifh either focial or felfifh pleafure, ei- ^her malicious or friendly, or lafcivious, or fublime pleafure; that is, they give us pleafure mixed with Other emotions, or they give us unmixed pleafure, without occasioning any other emotions or exertions at the fame-time. This unmixed pleafure, if it be great, becomes painful, like all other animal motions from flimuli of" every kiad ; and if no other exer- tions are occafioned at the fame time, we ufe the exertioa of laughter to relieve this pain. Hence laughter is occafioned by fuch wit as excites fimple pleafure without any othex emotion, fuch as pity, love, SECT. XXXI V.i. DISEASES OF VOLITION. love, reverence. For fublime ideas are mixed with admiration, beautiful ones with love, new ones with lurprife ; and thefe exertions of our ideas prevent the aclion of laughter from being neceflary to re- lieve the painful pleafure above defcribed. Whence laughable wit confifts of frivolous ideas, without con- nections of any confequence, fuch as puns on words, or on phrafes, incongruous junctions of ideas; on which account laughter is fo frequent in children. Unmixed pleafure lefs than that, which taufes laughter, caufes fleep, as in linging children to fleep, or in flight intoxication from wine or food. See Se&. XVIII. 12. 5. If the pains, or difagreeable fenfations, above defcribed, do not obtain a temporary relief from thefe convulfive exertions of the mufcles, thofe con- vuliive exertions continue without remiilion,and one kind of catalepfy is produced. Thus when a nerve or tendon produces great pain by its being inflamed or wounded, the patient fets his teeth firmly toge- ther, and grins violently, to diminilh the pain ; and if the pain is not relieved by this exertion, no relax- ation of the maxillary mufcles takes place, as in the convulfions above defcribed, but the jaws remain firmly fixed together. This locked jaw is the mofl frequent inftance of cataleptic fpafm, becaufe we are more inclined to exert the mufcles fubfervient to maftication from their early obedience to violent efforts of volition. But in the cafe related in Se&. XIX. on Reverie, the cataleptic lady had pain in her upper teeth ; and preffing one of her hands vehemently again ft her cheek-bone to diminifh this pain, it remained in that attitude for about half an hour twice a day, till the painful paroxyfm was over. I have this very day feen a young lady in this difeafe, (with which me has frequently been affiift- ed,) Ibe began to-day with violent pain mooting from one 483 DISEASES OF VOLITION. SECT. XXXIV. r. one fide of the forehead to the occiput, and after various fkuggles lay on the bed with her fingers and wrifts bent and fliif for about two hours ; in other refpedts fhe feemed in a fyncope with a natural pulfe. She then had intervals of pain and of fpafm, and took three grains of opium every hour till fhe had taken nine grains, before the pains and fpafm ceafed. There is, however, another fpecies of fixed fpafm, which differs from the former, as the pain exifts in the contra&ed mufcle, and would feem rather to be the confequence than the caufe of the contrac- tion, as in the cramp in the calf of the leg, and in many other parts of the body. In thefe fpafms it fhould feetn, that the mufcle itfelf is firft thrown into contraction by fome.difa- greeable fenfation, as of cold ; and that then the violent pain is produced by the great contraction of the mufcular fibres extending its own tendons, which are faid to be fenfible to extenfion only j and is further explained in Sect. XVIII. 15. 6. Many inftances have been given in this work, •where after violent motions excited by irritation, the organ has become quiefcent to lefs, and even to the great irritation, which induced it into violent motion ; as after looking long at the fun or any bright colour, they ceafe to be feen ; and after re- moving from bright day-light into a gloomy room, the eye cannot at firft perceive the objects, which ftirnulate it lefs. Similar to this is the fyncope, which fucceeds after the violent exertions of our, voluntary motions, as after epileptic fits, for the power of volition acts in this cafe as the ftimulus in the other. , This fyncope is a temporary palfy, or apoplexy, which ceafes after a time, the mufcles re- covering their power of being excited into action by the efforts of volition ; as the eye in the circum- ftance above mentioned recovers in a little time its power of feeing objects in a gloomy room, which were SF.CT. XXXIV. i. DISEASES OF VOLITION* were invifible immediately after coming out of a ftronger light. This is owing to an accumulation of fenforial power during the inaction of thofe fibres, which were before accuftomed to perpetual exerti- ons, as explained in Seel. XII. 7. I. A ilighter de- gree of this difeafe is experienced by every one after great fatigue, when the mufcles gain fuch in- ability to further adlion, that we are obliged to reft them for a while, or to fummon a greater power of volition to continue their motions. In all the fyncopes, which I have feen induced after convulfive fits, the pulfe has continued natu- ral, though _the organs of fenfe, as well as the loco<- motive mufcles, have ceafed to perform their func- tions ; for it is necefifavy for the perception of ob- jecls, that the external organs of fenfe fhould be properly excited by the voluntary power, as the eye- lids muft be open, and perhaps the mufcles of the eye put into aclion to diftend, and thence give greater pellucidity to the cornea, which in fyncoper as in death, appears flat and lefs tranfparent. The tympanum of the ear alfo feems to require a volun- tary exertion of its mufcles, to gain its due tenfion, and it is probable the other external organs of fenfe require a (imilar voluntary exertion to adapt them to the diftincl perception of objedls. Hence in fyncope as in fleep, as the power of volition is fufpended, no external objecls are perceived. See Seel. XVIII. 5. During the time which the patient lies in a fainting fit, the fpirit of animation becomes accumulated ; and hence the mufcles in a while be- come irritable by their ufual Simulation, and the fainting fit ceafes. See Seel. XII. 7. i. 7. If the exertion of the voluntary motions has been dill more energetic, the quiefcence, which fuc- ceeds, is fo complete, that they cannot again be excited into aclion by the efforts of the will. In this manner the palfy, and apoplexy (which is an univerfal 490 DISEASES OF VOLITION. SECT. XXXIV. i. universal palfy) are frequently produced after con- vulfions, or other violent exertions ; of this I (hall add a few inftances. Platernus mentions fome, who have died apoplec- tic from violent exertions in dancing ; and Dr. Mead, in his Effay on Poifons, records a patient in ihe hydrophobia, who at one effort broke the cords which bound him, and at the fame inftant expired, And it is probable, that thofe, who have expired from immoderate laughter, have died from this paralyfis confequent to violent exertion. Mrs. Scott of Stafford was walking in her garden in per- fect health with her neighbour Mrs. ; the lat- ter accidentally fell into a muddy rivulet, and tried in vain to difengage herfelf by the affiltance of Mrs. Scott's hand. Mrs. Scott exerted her utmoft power for many minutes, firft to aflift her ffiend, and next to pi event herfelf from being pulled into the mo- rafs, as her diftreffed companion would not difen- gage her hand. After other affiftance was procured by their united fcreams, Mrs. Scott walked to a chair about twenty yards from the brook, and was feized with an apoplectic flroke: which continued many days, and terminated in a total lofs of her right arm, and her fpeech ;• neither of which me ever after perfectly recovered. It is faid, that many people in Holland have died after fkating too long or too violently on their fro- zen canals ; it is probable the death of thefe, and of others, who have died fuddenly in fwimming, has been owing to this great quiefcence or paralyfis j which has fucceeded very violent exertions, added to the concomitant cold, which has had greater effect after the fufferers had been heated and ex- haufted by previous exercife. I remember a young man of the name of Nairne at Cambridge, who walking on the edge of a barge fell into the river. • His coufm and fellow-ftudent of the SECT. XXXIV. i: DISEASES OF ^VOLITION. 491 the fame name, knowing the other could not fwim, plunged into the water after him, caught him by his clothes, and approaching the bank by a vehe- ment exertion propelled him fafe to the land, but that iuftant, feized, as was fuppofed, by the cramp, or paralyfis, funk to rife no more. The reafon why the cramp of the mufcles, which compofe the calf of the leg, is fo liable to afte£ fwimmers, is, be- caufe thefe mufcles have very weak antagonifls, and are in walking generally elongated again after their contraction by the weight of the body on the ball of the toe, which is very much greater than the re- fiftance of the water in fwimming. See Section XVIII. 15. It does not follow that every apoplectic or para- lytic attack is immediately preceded by vehement exertion ; the quiefcence, which fucceeds exertion, and which is not fo great as to be termed paralyfis, frequently recurs afterwards at certain periods ; and by other caufes of quiefcence, occurring with thofe periods, as was explained in treating of the pa- roxyfms of intermitting fevers ; the quiefcence at length becomes fo great as to be incapable of again being removed by the efforts of volition, and com- plete paralyfis is formed. See Section XXXII. 3. 2. Many of the paralytic patients, whom I have feen, have evidently had difeafed livers from the too fre- quent potation of fpirituous liquors ; fome of them have had the gutta rofea on their faces and breads ; which has in fome degree receded either fpontane- oufly, or by the ufe of external remedies, and the paralytic ftroke has fucceeded ; and as in feveral perfons, who have drank much vinous fpirits, I have obferved epileptic fits to commence at about forty or fifty years of age, without any hereditary taint, from the flimulus, as I believed, of a difeafed liver ; I was induced to afcribe many paralytic cafes to the famefource; which were not evidently the effect: VOL. I. K k of DISEASES OF VOLITION. SECT.XX^XIY. * of age, or of unacquired debility. And the account given before of d replies, which very frequently are owing to a paralyfis of the abforbent fyftem, and are generally attendant on free drinkers of fpiritu- ous liquors, confirmed me in this opi-nion. The difagreeable irritation of a difeafed liver pro- duces exertions and confequent quiefcenee ; thefe by the accidental concurrence of other caufes of qui- efcence, as cold, folar or lunar periods, inanition, the want of their ufual portion of fpirit of wine> at length produces paralyfis. This is further confirmed by obferving, that the x mufcies, we moft frequently, or moll powerfully exert, are mod liable to palfy ; as thofe oi the voice and of articulation, and of thofe paralytics which I have- feen, a much greater proportion have loft the ufe of their right arm; which is fo much more generally exerted than the left. I cannot difmifs this fubje£fc without obfervingy that after a paralytic ftroke, if the vital powers are not much injured, the patient has all the move* mems of the affecled limb to learn over again, jufl as in early infancy ; the limb is firft moved by the irritation of its mufcies, as in flretching, (of which a cafe was related in Sedlion VII. i. 3.) or by the eleftrie concuifion ; a1 terwards it becomes obedient to fenfation, as in violent danger or fear ; and laftly, the mufcies become again aflociated with volition, and gradually acquire their ufual habits of adliiig together. Another phsenomenon in palfies is, that when the limbs of one fide are difabled, thofe of the other are in perpetual motion. This can only be explain- ed from conceiving that the power of motion, what- ever it is, or wherever it refides, and which is ca- pable of being exhaufted by fatigue, and accumu- lated in reft, is now lefs expended, whilfl one half of the body is capable of receiving its due propor- tion SECT. XXXiV.2. DISEASES OF VOLITION. 493 tion of it, and is hence derived with greater cafe or in greater abundance into the limbs, which remain unaffected. II. i. Theexcefsor defect of voluntary exertion produces fimilar effects upon the fenfual motions, or ideas of the mind, as thofe already mentioned up- on the mufcular fibres. Thus when any violent pain, ariiing from the defect of fome peculiar fli- mulus, exiils either in the mufcular or fenfual fyf- tems of fibres, and which cannot be removed by acquiring the defective ftimulus } as in fome confti- tutions convulfions of the mufcles are produced to procure a temporary relief, fo in other conftitutions vehement voluntary exertions of the ideas of the mind are produced for the fame purpofe; for dur- ing this exertion, like that of the mufcles, the pain either vanifhes or is diminifhed : this violent exer- tion conflitutes madnefs ; and in many cafes I have ieen the madnefs take place, and the convulfions ceafe, and reciprocally the madnefs ceafe, and the convulfions fupervene. See Sect. III. 5. 8. 2. Madnefs is diftiuguifhable from delirium, as in the latter the patient knows not the place where he refides, nor the perfons of his friends or attend- ants, nor is confcious of any external objects, ex- cept when fpoken to with a louder voice, or Simu- lated with unufual force, and even then he foon relapfes into a ftate of inattention to every thing about him. VVhilit in the former he is perfectly ienlible to every thing external, but has the volun- tary powers of his mind intenfely exerted n fome particular object of his defire or averfion, he har- bours in his thoughts a fufpicion of all mankind, left they mould counteract his defigns ; and while he keeps his intentions and the motives of his ac- tions profoundly fecret ; he is perpetually (tudying the means of acquiring the object of his wifh, or of preventing or revenging the injuries hefufpedts. Kk 2 3. A DISEASES OF VOLITION. SECT. XXXIV. '». 3. A late French philofopher, Mr» Helvet'ms, has deduced almoft all our adlions from this principle of their relieving us from the ennui or taedium vitas ; and true it is, that our defires or aver lions are the motives of all our voluntary a&ions ; and human nature feems to excel other animals in the more facil ufe of this voluntary power, and on that ac- count is more liable to infanity than other animals. But in mania this violent exertion of volition is expended on miftaken objects, and would not be re- lieved, though we were to gain or efcape the ob- jects, that excite it. Thus I have feen two instances of madmen, who conceived that they had the itchy and feveral have believed they had the venereal in- fection, without in reality having a fymptom of either of them. They have been perpetually think- ing upon this fubject, and fome of them were in vain falivated with defign of convincing them to the contrary. 4. In the minds of mad people thofe volitions alone exift, which are unmixed with fenfation; im- moderate fufpieion is generally the firft fymptom, and want of fhame, and want of delicacy about cleanlinefs* Sufpicion is a voluntary exertion of the mind, arifing from the pain of fear, which it is exerted to relieve : Ihame is the name of a peculiar difagreeable fenfation, fee Fable of the Bees, and deli- cacy about cleanlraefs arifes from another difagree- able fenfation. And therefore ate not found in the minds of maniacs, which are employed folely in voluntary exertions. Hence the moil modeft wo- men in this difeafe walk naked arnongft men with- out any kind of concern, ufe obfcene difcourfe, and have no delicacy about their natural evacuations. 5. Nor are maniacal people more attentive to their natural appetites, or to the irritations which furround them, except as far as may refpecl their fufpicions or defignsj for the violent and perpetual exertions SECT. XXXIV. 2. DISEASES OF VOLITION. 495 exertions of their voluntary powers of mind prevent their perception of almoft every other object, either of irritation or of fenfation. Hence it is that they bear cold, hunger, and fatigue, with much greater pertinacity than in their fober hours, and are left* injured by them in refpect to their general health. Thus it is afierted by hiftoiians, that Charles the Twelfth of Sweden flept on the fnow, wrapped only in his cloak, at the liege of Frederick ft ad, and bore extremes of cold, and hunger, and fatigue, under which numbers of his foldiers perimed; becaufe the king was infane with ambition, but the foldier had no fuch powerful ftimulus to preferve his fyftem from debility and death. 6. Befides the infanities arifing from exertions in ronfequence of pain, there is alfo a pleafurable in- fanity, as well as a pleafurable delirium ; as the in* fanity of perfonal vanity, and that of religious fana- ticifm. When agreeable ideas excite into motion the fenforial power of fenfation, and this again caufes other trains of agreeable ideas, a conftant ftream of pleafurable ideas fucceeds, and produces pleafurable delirium. So when the fenforial power of volition excites agreeable ideas, and the pleafure thus produced excites more volition in its turn, a conftant flow of agreeable voluntary ideas fucceeds ; which when thus exerted in the extreme conftitutes infanity. Thus when our mufcular a&ions are excited by our fenfations of pleafure, it is termed play; when they are excited by our volition, it is termed work ; and the former of thefe is attended with lefs fa- tigue, becaufe the mufcular actions in play produce in their turn more pleafurable fenfation ; which again has the property of producing more mufcular acuon. An agreeable inftance of this I faw this morning. A little boy, who was tifed with walk- ing, begged of his papa to carry him. " Here," fays DISEASES OF VOLITION. Spcr. XXXIV. a. fays the reverend doctor, " ride upon my gold- headed cane ;" and the pleafed child, putting it between his legs, galloped away with delight, and complained no more of his fatigue. Here the aid of another fenforial power, that of pleafurable fen- fation, fuperadded vigour to the exertion of exhauft- ed volition. Which could otherwife only have been excited by additional pain, as by the laih of flavery. On this account, where the whole fenforial power has been exerted on the contemplation of the pro? mifed joys of heaven, the faints of all perfecuted religions have borne the tortures of martyrdom with otheiwife unaccountable firmnefs. 7. There are fome difeafes, which obtain at leaft a temporary relief from the exertions of infanity j many inftances of diopfies being thus for a time cured are recorded. An elderly woman labouring •with afcites I twice faw relieved for fome weeks by infanity, the dropfy ceafed fpr feveial weeks, an4 recurred again, alternating with the infanity. A man afflicted with difficult refpiration on lying down, with very irregular pulfe, and cedematous legs, whom I faw this day, has for above a week been, much relieved in refpect to all thofe fymptoms by the accefiion of infanity, which is fhewn by inordi: nate fufpicion, and great anger. Jn cales of Common temporary anger the increaf- ed action of the arterial fyftem is feen by the re4 Ikin, and increafed pulfe., with the immediate in* creafe of mufcular activity. A friend of mine, when he was painfully fatigued by riding on horfeback, •was accuftomed to, call up ideas into his mind, which ufed to excite his anger pr indignation, and thus for a time at leaft relieved the 'pain of fatigue. By this temporary infanity, the effecl of the volun- tary power upon the whole of his fyftem was in- creafed ; as in the cafes of dropfy above mentioned, it would appear, that the increafed action of the voluntary SECT. XXXIV. 2. DISEASES OF VOLITION. 497 voluntary faculty of the feriforium affetfed the ab- forbent fyitem, as well as the fecerning one. 8. In refpect to relieving inBammatory pains, and removing fever, I have feen many mftances, as men- tioned in Seel XII. 2. 4. One lady, whom I at- tended, had twice at fome years interval a locked jaw, which relieved a pain on her fternum with pe- ripneumony. -Two other ladies I faw, who towards the end of violent peripneumony, in which they frequently loft blood, were at length cured by infa- nity fupervening. In the former the increafed vo- luntary exertion of the mufcles of the jaw, in the latter that of the organs of fenfe, removed the dif- eafe ; that is, the dilagreeable fenfation, which had produced the inflammation, now excited the volun- tary power, and thefe new voluntary exertions em- ployed or expended the fuperabundant fenforial pow- er, which had previoufly been exerted on the arte- rial fyitem, and, caufed inflammation. Another cafe, which I think worth relating, was of a young man about twenty ; he had laboured under an irritative fever with debility for three or four weeks, with very quick and very feeble pulfe, and other ufual fymptorns of that fpecies of typhus, but at this time complained much and frequently of pain of his legs and feet. When thole who at- tended him were nearly in defpair of his recovery, I obferved with pleafure an inlanity of mind fuper- yene: which was totally different from delirium as he knew his friends, calling them by their names, and the room in which he lay, but became vio- lently fufpicious of his attendants, and calumniated with vehement oaths his tender mother, who fat weeping by his bed. On this his pulfe became flower and firmer, but the quicknefs did not for fome time intirely ceafe, and he gradually recovered. In this cafe the introduction of an increafed quan- tity of the power of volition gave vigour to thofe movements 498 DISEASES OF VOLITION. SECT. XXXIV. 3, movements of the fyftem, which are generally only a^uated by the power of irritation, and of affocia- tion. Another cafe I recollect of a young man, about twenty-five, who had the fcarlet-fever, with very quick pulfe, and an univerfal eruption on his (kin, and was not without reafon efteemed to be in great danger of his life. After a few days an infanity fupervened, which his friends miftook for delirium, and he gradually recovered, and the cuticle peele4 off. From thefe and a few other cafes I have always efteemed infanity to be a favourable llgn in fevers, and have cautioufly diftinguifhed it from delirium. III. Another mode of merital exertion to relieve pain, is by producing a train of ideas not only by the efforts of volition, as in infanity ; but by thofe of fenfation likewife, as in delirium and deep. This mental effort is termed reverie, or fomnambulation, and is defcribed more at large in Seel. XIX. on that fubject. But I fhall here relate another cafe of that wonderful difeafe, which fell yefterday under my eye, and to which I have feen many analogous ali- enations of mind, though not exadlly fimilar in all circurriftances. But as all of them either began or; terminated with pain or convulfion, there can be no doubt but that they are of epileptic origin, and conftitute another mode of mental exertion to re- lieve fome painful fenfation. i. Mafter A. about nine years old, had been feized at feven every morning fpr ten days ttith un- common fits, and had had flight returns in the after- noon. They were fuppofed to originate from worms, and had been in vain attempted to be removed by vermifuge purges. As his fit was expected at feven yefterday morning, I faw him before that hour ; he was aileep, feemed free from pain, and his pulfe natural. About feven he began to complain of pain about his navel, or more to the left fide, and in a few SECT.XXX1V.3, DISEASES OF VOLITION. 499 few minutes had exertions of his arms and legs like fwimming. He then for half an hour hunted a pack of hounds ; as appeared by his hallooing, and calling the dogs by their names, and difcourfing with the attendants of the chafe, clefciibing exadly a day of hunting, which (I was informed) he had witnefled a year before, going through all the moft minute circumftances of it ; calling to people, \vho \vere then prelent, and lamenting the abfence of others, who were then alfo abfent. After this fcene he imitated, as he lay in bed, fome of the plays of boys, as fwimming and jumping. He then fung an Englifh and then an Italian fong ; part of which with his eyes open, and part with the.m clofed, but could not be .awakened or excited by any violence, which it was proper to ufe. After about an hour he came fuddenly to him- felf with apparent furprife, and feemed quite igno- rant of any part of what had paffed, and after bein^ apparently well for half an hour, he fuddenly fell into a great ftupor, with flower pulfe than natural, and a flow moaning refpiration, in which he conti- nued about another half hour, and then recovered. The fequel of this difeafe was favourable ; he was direcled one grain of opium at fix every morning, and then to rife out of bed ; at half paft fix he was directed fifteen drops of laudanum in a glafs of wine and water. The fit ft day the paroxyfm became fhorter, and lefs violent. The dofe of opium was increafed to one-half more, and in three or four days the fits left him. The bark and filings of iron were alfo exhibited twice a day ; and I believe the complaint returned no more 2. In this paroxyfm it muft be obfcrved, that he began with pain, and ended with ftupor, in both circumftances refcmbling a fit of epilepfy. And that therefore the exertions both of mind and body, both the voluntary ones, and thofe immediately ex- cited 5oo DISEASES OF VOLITION. SECT. XXXIV. j. cited by pleafurable fenfation, were exertions to re- lieve pain. Tbe hunting fcene appeared to be rather an aft of memory than of imagination, and was therefore rather a voluntary exertion, though attended with the pleafarable eagernefs, which was the confe- quence of thofe ideas recalled by recollection, and not the caufe of them. Thefe ideas thus voluntarily recolle&ed were fuc- ceeded by fenfations of pleafure, though his fenfes \vere unaffected by the ftimuli of vifible or audible obje&s ; or fo weakly excited by them as not to produce fenfation or attention. And the pleafure thus excited by volition produced other ideas and other motions in confequence of the tentbrial power of fenfation. Whence the mixed catenations of vo^ luntary and fenfitive ideas and mufcular motions in reverie ; which, like every other kind of vehement exertion, contribute to relieve pain, by expending a {arge quantity of fenforial power. Thofe fits geneialiy commence during fieep, from, whence I fuppofe they have been thought to have, fome connection with ileep, and have thence been termed Somnambulifm ; but their commencement during ileep is owing to our increafed excitability by internal fenfations at that time, as explained in Sect XVIII. 14 and 15, and nof to any fimilitude between reverie and deep. 3. I was once concerned for a very elegant and ingenious young lady, who had a reverie on alter- nate days, which continued nearly the whole day ; and as in her days of difeafe (lie took up the fame kind of ideas, which (he had convened about on the alternate day before, and could recollecl nothing of them on her well-day ; fhe appeared to her friend $ to poffefs two minds. This cafe alfo was of epi- leptic kind, and was cured, with fome relapfes, by ppium. 3. DISEASES OF VOLITION. 501 opium adminiftered before the commencement of the paroxyfm. 4. Whence it appears, that the methods of re* lieving inflammatory pains, is by removing all fli- mulus, as by venefe&ion, cool air, mucilaginous diet, aqueous potation, filence, darknefs. The methods of relieving pains from defect of fli- mulus is by fupplying the peculiar Himulus required, as of food, or warmth. And the general method of relieving pain is by exciting into adtion fome great part of the fyftem, for the purpofe of expending a part of the fenfona! power. This is done either by the exertion of the voluntary ideas and mufcles, as in infanity and con- vulfion y or by exerting both voluntary and fenfitive motions, as in reverie; or by exciting the irritative motions by wine or opium internally, and by the warm bath or blifters externally ; pr laftly, by exr citing the fenlitive ideas by good news^ affe&ing , or agreeable paflions. SECT. DISEASES OF ASSOCIATION. SECT, XXXV. i, SECT. XXXV* DISEASES OF ASSOCIATION i . Sympathy or confent of parts. Primary and ft* condary parts of an aflbciated train of motions reci- procally affeft each other. Parts of irritative trains of motion ajfeft each other in four ways. Sympa- thies of the Jkin and jlomach. Flujhing of the face after a meal. Eruption of the fmall-pox on the face. Chillnefs after a meaL 2. Per tigo from intoxication. 3. Absorption from the lungs aqd pericardium by emetics. In vomiting the a&ions of the jlomach are decreafed, not increafsd. Digejlionjlrengthened after an emetic. Vomiting from clejiciency of fenforial power. 4. 'Dyfpnceafrom cold bathing. Slow pulfe from digitalis. Death from gout in the flomack. 1 1. i. Primary and fzcondary parts of fenfitwe affo- ciations affect each other. Pain from gall-Jlone,froi% urinary Jlone. Ifemicrania. Painful epilepfy. 2. Gout and red face from injlamed liver. Shingles from inflamed kidney. ^. Cory za from cold applied to the feet. Pleurify, ^Hepatitis. 4. Pain of fhoul- ders from injlamed liu$r. III. Difeafes from the ajjbciations of I. i. MANY fynchronous and fucceffive motions of our mufcular fibres, and of our organs of fenfe, or ideas, become affociated fo as to form indiflblu- ble tribes or trains of action, as fhewn in Se6tion X. on Aflbciate Motions. Some conftitutions more cafily edablifh thefe afibciadons, whether by volun- tary, fenfitive, or irritative repetitions, and fome more SECT. XXXV. i. DISEASES OF ASSOCIATION. 503 more eafily lofe them again, as fhewn in Se&ion . XXXI. on Temperaments. When the beginning of fuch a train of actions be- comes by any means difordered, the fucceeding pare is liable to become disturbed in confequence, and this is commonly termed fympathy or confent of parts by the writers of medicine. For the more clear undemanding of thefe fympathies we mult confider a tribe or train of a&ions as divided into two parts, and call one of them the primary or original motions, and the other the fecondary or fym pathetic ones. The primary and fecondary parts of a train of irritative a&ions may reciprocally affe& each other in four different manners, i. They may both be exerted with greater energy than natural* 2. The former may aft with greater, and the latter with lefs energy. 3. The former may aft with lefs, and the latter with greater energy. 4. They may both act with lefs energy than natural. I fhall now give an example of each kind of thefe modes of adhon, and endeavour to mew, that though the primary and fecondary parts of thefe trains or tribes of mo- tion are conne&ed by irritative affociation, or their previous habits of acting together, as defcribed in Sect. XX. on Vertigo. Yet that their a&ing wLh fimilar or diffimilar degrees of energy, depends on the greater or lefs quantity of fenforial power, which the primary part of the train expends in its exer- tions. The actions of the ftomach conftitute fo important a part of the affbciaiions of both irritative and fen- fitive motions, that it is faid to fympathize with alrnoft every part of the body; the firft example, which I ffiall adduce to fhew that both the primary and fecondary parts of a train of irritative affocia- tions of motion ael with increaled energy, is taken from the confent of the fkin with this organ. When the $»4 DISEASES OF ASSOCIATION. SECT. XX&V. t. the adlion of the -fibres of die ftomach is increafed, as by the fHmulus of a full meal, the exertions of the cutaneous arteries of the face become in creafed by their irritative afibciafions with thofe of the fto- mach, and a glow or flaming of the face fucceeds. For the fmall veflels of the fkin of the face having been more accultomed to the varieties* of action, from their frequent expofure to various degrees of cold and heat become more eafily excited into in- creafed a&ion, than thofe of the covered parts of our bodies* aad thus aft with more energy from their irritative or fentltive altbciations with the fto- mach. On this account in fmall-pox the eruption in confequence of the previous affection of the Ito- mach breaks out a day fooner on the face than on the hands, and two days fooner than on the trunk, and recedes in fimilar times after maturation. But fecondly, in weaker confutations, that is, in thofe who poffefs lefs fenforial power, fo much of it is expended in the increafed a6lions of the fibres of the ilomach excited by the ftimulus of a meal, that a fenfe of chilnefs fucceeds inflead of the uni- verfal glow above mentioned ; and thus the fecon- dary part of the affociated train of motions is dimi- nilhed in energy, in confequence of the increafed activity of the primary part of it. 2, Another inftance of a fimilar kind, where the fecondary part of the train ads with lefs energy in confequence of the greater exertions of the primary part, is the vertigo attending intoxication ; in this circumflance fo much fenforial power is expended on the Romach, and on its neareft or more ihongly affociated motions, as thofe of the fubcutaneous vef- fels, and probably of ths membranes of fome inter- nal vifcera, that the irritative motions of the retina become imperfectly exerted from deficiency of fen- forial power, as explained in Seel. XX. and XXI. 3. pn Vertigo and on Drunkennefs, and hence the dag- gering SECT. xxxv. i. DISEASES OF ASSOCIATION. 505 gering inebriate cannot completely balance himfelf by fuch indiftinft vifion. 3. An inftance of the third circumftance, where the primary part of a train of irritative motions ads with lefs, and the fecondary part with greater ener- gy, may be obferved by making the following ex- periment. If a perfon lies with his arms and fhoul- ders out of bed, till they become cold, a temporary coryza or catarrh is produced ; fo that the paflage of the noftrils becomes totally obftruded ; at lead this happens to many people ; and then on covering the arms and fhoulders, till they become warm, the paflage of the noftrils ceafes again to be ob- ftru&ed, and a quantity of mucus is difcharged from them. In this cafe the quiefcence of the veflels of the (kin of the arms and moulders, occafioned by expofute to cold air, produces by irritative aflbci- ation an increafed action of the veflels of the mem- brane of the noftrils ; and the accumulation of fen- foriai power during the torpor of the arms and (houlders is thus expended in producing a temporary coryza or catarrh. Another inftance may be adduced from the fym- pathy or confent of the motions of the ftomach with other more diftant links of the very extenlive tribes or trains of irritative motions affociated with them, defcribcd in Seel. XX. on Vertigo. When the actions of the fibres of the ftomach are dimi- nifhed or inverted, the adions of the abforbent veflels, which take up the mucus from the lungs, pericardium, and other cells of the body, become increafed, and abfoib the fluids accumulated in them with greater avidity, as appears from the exhibition of foxglove, antimony, or other emetics in cafes of anafarca, attended with unequal pulfe and difficult ref pi ration. That the act of naufea and vomiting is a decreaf- ed exertipn of the fibres of the ftomach may be thus deduced ; So6 DISEASES OF ASSOCIATION. SECT. XXXV. i; deduced j when an emetic medicine is adminiflered, it produces the pain of ficknefs, as a difagreeable tafte in the mouth produces the pain of naufea ; thefe patns, like thofe of hunger, or of cold, or like thofe, which are ufually termed nervous, as the headrach or hemicrama, do not excite the organ in- to greater aclion ; but in this cafe I imagine the pains of ficknefs or of naufea counteracl or deflroy the pleafurable fenfation. which feems neceffary to digeition, as fhewn in Sett. XXXIII. i. f. The pe- riftaltic motions of the fibres of the ftomach be- come enfeebled by the \vant of this ilimulus of pleafurable fenfation, and in confequence flop for a time, and then become inverted ; for they cannot become inverted without being previoufly flopped. Now that this inverfion of the trains of motion of the fibres of the ftomach is owing to the deficiency . of pleafurable fenfation is evinced from this circum- fiance, that a naufeous idea excited by words wilt produce vomiting as effectually as a naufeotis drug. Hence it appears, that the act of naufea or vo* miting expends lefs fenforial power than the ufual periflaltic motions of the ftomach in the digeftion of our aliment ; and that hence there is a greater quantity of fenforial power becomes accumulated in the fibres of the flomach, and more of it in confequence to fpare for the action of thofe parts of the fyftem, which are thus affociated with the ilomach, as of the whole abforbent feries of veflels, and which are at the fame time excited by their ufual flimuli. From this we can underftand, how after the ope- ration of an emetic the flomach becomes more irri- table and fenfible to the ftimulus, and the pleafure of food ; fince as the fenforial power becomes ac- cumulated during the naufea and vomiting, the digeftive power is afterwards exerted more forcibly for a time. It mould, however, be here remarked, that SECT. XXXV. a. DISEASES OF ASSOCIATION. 507 that though vomiting is in general produced by the defect of this ftimulus of pleafurable fenfation, as When a naufeous drug is adminiftered ; yet in long continued vomiting, as in fea-ficknefs, or from habi- tual dram-drinking, it arifes from deficiency of fen- foii.il power, "which in the former cafe is exhaufted by the increafed exertion of the irritative ideas of vifion, and in the latter by the frequent application of an unnatural ftimulus. 4. An example of the fourth circumftance above mentioned, where both the primary arid fecondary parts of a train of motions proceed with energy lefs than natural, may be obferved in the dyfpncea, which occurs in going into a very cold bath, and which has been defcribed and explained in Seel. XXXII. 3. 2* And by the increafed debility of the pulfations of the heart and arteries during the operation of an emetic. Secondly, from the flownefs and intermif- fion of the pulfations of the heart from the inceffant efforts to vomit occafioned by an overdofe of digi- talis. And thirdly, from the total floppage of the motions of the heart, or death, in confequence of the torpor of the ftomaeh, when affected with the commencement or cold paroxyfm of the gout. See Sea. XXV. 17. II. i. The primary and fecondary parts of the trains of fenfitive affociadon reciprocally affect each other in different manners, i. The increafed fen- fation of the primary part may eeafe, when that of the fecondary part commences. 2. The increafed action of the primary part may ceafe, when that of the feeondary part commences. 3. The primary part may have increafed fenfation, and the fecon- dary part increafed action. 4. The primary part may have increafed action, and the fecondary part increafed fenfation. Examples of the firft mode, where the increafed fenfation of the primary part of a.irain of fenfitive afTociation ceafes, when that of the fecondary part I. LI commences? DISEASES OF ASSOCIATION. SECT. XXXV. 2. commences, are not unfrequent ; as this is the ge- neral origin of thofe pains, which continue fome time without being attended with inflammation, fuch as the pain at the pic of the ftomach from a ftone at the neck of the gall-bladder, and the pain of ftrangury in the glans penis from a ftone at the neck of the urinary bladder. In both thefe cafes the part, which is alfecled fecondarily, is believed to be much more fenfible than the part primarily af- fected, as defcribed in the catalogue of difeafes, ClafsJI. i. i. H. and IV. 2. 2.2. and IV. 2. 2. 4. The hemicrania, or nervous heau-ach, as it is called, when it originates from a decaying tooth, is another difeafe of this kind ; as the pain of the carious tooth always ceafes, when the pain over one • eye and temple commences. And it is probable, that the violent pains, which induce convulfions in painful epilepfies, are produced in the fame man- ner, from a more fenfible part fympathizing with a difeafed one of lefs fenfibility. See Catalogue of Difeafes, Clafs IV. 2. 2. 8. and III. i. i. 6. The laft tooth, or dens fapientise, of the upper jaw moft frequently decays firft, and is liable to produce pain over the eye and temple of that fide. The laft tooth of the under jaw is alfo liable to produce a fimilar hemicrania, when it begins to de- cay. When a tooth in the upper jaw is the caufe of the beadach, a (lighter pain is fometimes per- ceived on the cheek-bone. And when a tooth in the lower-jaw is the caufe of headach, a pain fome- times affects the tendons of the mufcles of the neck, which are attached near the jaws. But the clavus hyilericus, or pain about the middle of the parietal bone on one fide of the head, I have feen produced by the fecond of the molares, or grinders, of the under jaw; of which I (hall relate the following cafe. See Clafs iV. 2. 2. 8. Mrs. ECT. XXXV. 2. DISEASES OF ASSOCIATION. Mrs. •, about 30 years of age, was feized with great pain about the middle of the right pa- rietal bone, which had continued a whole day be- fore I faw her, and was fo violent as to threaten, to occafion convulfions. Not being able to detect a decaying tooth, or a tender one, by examination with my eye, or by ftriking them with a tea-fpoon, and fearing bad confequences from her tendency to convulfion, I advifed her to extract the laft tooth of the under-jaw on the affected iide ; which was done without any good effect. She was then directed to lofe blood, and to take a brifk cathartic ; and after that had operated, about 60 drops of laudanum were given her, with large dofes of bark ; by which the pain was removed. In about a fortnight flie took a cathartic medicine by ill advice, and the pain returned with greater violence in the fame place, and, before I could arrive, as (he lived 30 miles from, me, (he fuffered a paralytic firoke; which affected her limbs and her face on one iide, and relieved the pain of her head. About a year afterwards I was again called to her on account of a pain as violent as before, ex- actly on the fame part of the other parietal bone. On examining her mouth I found the fecond molaris of the under-jaw on the fide before affected was now decayed, and concluded, that this tooth had occafioned the ftroke of the palfy by the pain and confequent exertion it had caufed. On this account I earneftly entreated her to allow the found molaris of the fame jaw oppofite to the decayed one to be extracted ; which was forthwith done, and the pain of her head immediately ceafed, to the aiionilhment of her attendants. In the cafes above related of the pain exifting in a part diflant from the feat of the difeafe, the pain is owing to defeft of the ufual motions of the pain- ful part. This appears from the coldnefs, palenefs, LI 3 and $IQ DISEASES OF ASSOCIATION. SECT, XXXV. 2. and emptinefs of the affe&ed veffels, or of the ex- tremities of the body in general, and from there being no tendency to jcn flam mar ion-. The increafed action of the primary part of thefe aiTociated mo- tions, as of the hepatic termination of the bik-du& from the ftimulus of a gall-ftone, or of the interior termination of die urethra from the ftimulos of a flone in the bladder, or laftlv, of a decaying tooth in hemicrania, deprives the fecondary part of thefe affociated motions, namely, the exterior terminati- ons of the bile-duel or urethra, or the pained mern- fcranes of the head in hemicrania, of their narural fhare of fenforial power : and hence the fecondary parts of thefe fenfttive trains of aiTociation become pained from the deficiency of their ufaal motions, which is accompanied with deficiency of fecretions and of heat. See Sett. IV. 5. XII 5. 3. XXXIV. u Why does the pain of the primary part of the affociation ceafe, when that of the fecondary part commences ? This is a queftion of intricacy, but' perhaps not inexplicable. The pain of the primary part of thefe affociated trains of motion was owing to too great fUmutus, as of the flone at the neck of the bladder, and was consequently caufed by too- great a&ion of the pained part. This greater ac- tion than natural of the primary part of thefe affo- eiated motions, by employing or expending the fen- forial power of irritation belonging to the whole affociated train of motions, occafioned torpor, and confequent pain in the fecondary part of the affoci- ated train ; which was poffeffed of greater feniibility than the primary part of it. Now the great pain of the fecondary part of the train, as foon as it commences, employs or expends the fenforial pow- er of fenfation belonging to the whole affociated train of motions ; and in confequence the motions of the primary part, though increafed by the ftimu- lus Stc-r.XXXV. 2. DISEASES OF ASSOCIATION. 511 lus of an extianeousbody, ceafe to be accompanied with pain or fecfation. If this mode of reafoning bejuft, it explains a curious fact, why when two parts of the body are ftrongly ftimulated, the pain is felt only in one of them, though it is polEble by voluntary attention it may be alternately perceived in them both. In the fame manner, when two new ideas are prefent- ed to us from the IHmulus of external bodies, we attend to but one of them at a time. In other words, when one fet of fibres, whether of the muf- cles or organs of fenfe, contract fo ftrongly as to excite much fenfation ; another fet of fibres con- tracting more weakly do not excite fenfaiion at all, becaufe the fenforial power of fenfation is pre-occu- pied by the firft fet of fibres. So we cannot will more than one effect at once, though by aflbciations previoufly formed we can inove many fibres in corn- bin a tiofi. Thus in the inftances above related, the termina- tion of the bile duel: in the duodenum, and the ex- terior extremity of the urethra, are more fenfible than their other terminations. When thefe parts are deprived of their ufual motions by deficiency of fenforial power, as above explained, they become painful according to law the fiah in Section IV. and the lefs pain, originally excited by the ftimulus of concreted bile, or of a ftone at their other extre- mities, ceafes to be perceived. Afterwards, howe- ver, when the concretions of bile, or the ftone on the urinary bladder, become more numerous or larger, the pain from their increafed flimulus be- comes gieater than the aflbciated pain ; and is then felt at the neck of the gall bladder or urinary blad- der ; and the pain of the glans penis, or at the pit of the nomach ceafes to be perceived. 2. Examples of the fecond mode, where the in- creafed action of the primary part of a train of fenfnive $ra DISEASES OF ASSOCIATION. SECT. XXXV. 2. fenfitive aflbciation ceafes, when that of the fecon- dary part commences, are alfo n.ot unfrequent ; as this is the ufual manner of the tranflation of in* flammations from internal to external parts of the fyftem, fuch as when an inflammation of the liver or ftomach is tranflated to the membranes of the foot, and forms the gout ; or to the (kin of the face, and forms the rofy drop ; or when an inflam- mation of the membranes of the kidneys is tranf- lated to the ikin of the loins, and forms one kind of herpes, called (hingles ; in thefe cafes, by whate- ver caufe the original inflammation may have been produced, as the fecondary part of the train of fen. iitive aflbciation is more fenfible, it becomes ex- erted with greater violence than the firft part of it j and by both its increafed pain, and the increafed motion of its fibres, fo far diminifhes or exhaufts the fenforial power of fenfation, that the primary part of the train being lefs fenfible ceafes both to feel pain, and to aft with unnatural energy. 3. Examples of the third mode, where the pri- mary part of a train of fenfitive aflbciation of mo* lions may experience increafed fenfaiion, and the fecondary parr increafed action, are likewife not un- frequent ; as it is in this manner that moil inflam- mations commence. Thus, after ftanding fome time in fnow, the feet become affected with the pain of cold, and a common coryza, or inflammation of the membrane of the noftrik, fucceeds. It is probable that the internal inflammations, as pleurifies, or he- patitis, which are produced after the cold paroxyfm of fever, originate in the fame manner from the Sympathy of .thof$ parts with fome others, which were previoufly pained from quiefcence ; as hap- pens to various parts of the fyftem during the cold fits of fevers. In thefe cafes it would feem, that the fenforial power of fenfation becomes accumu- lated during the pain of cold, as the torpor of the veffeli SKCT. XXXV. 3. DISEASES OF ASSOCIATION. -513 veflels occafioned by the defect of heat contributes to theincreafe or accumulation of the fenforial pow- er, of irritation, and that both thefe become exerted on fome internal part, which was not rendered tor- pid by the cold which affected the external parts, nor by its aflbciation with them ; or which fooner recovered its fenfibility. This requires further con- fideration. 4. An example of the fourth mode, or where the primary part of a feniitive affociation of motions may have increafed action, and the fecondary part increafed fenfation, may be taken from the pain of the fhoulder, which attends inflammation of the membranes of the liver, fee Clafs IV. 2. 2. 9. ; in this circumftance fo much fenforial power feems to be expended in the violent actions and fenfations of the inflamed membranes of the liver, that the mem- branes affociatcd with them become quiefcent to their ufual ftirnuli, and painful in coufequence. There may be other modes in which the primary and fecondary parts of the train of aflbciated fenii- tive motions may reciprocally affect each other, as may be feen by looking over Clafs IV. in the cata- logue of difeafes ; all which may probably be re- folved into the plus and minus of fenforial power, but we have not yet had fufficient obfervations made upon them with a view to this doctrine. III. The aflbciated trains of our ideas may have fympathies, and their primary and fecondary parts affect each other in fome manner fimilar .to thofe above defcribed ; and may thus occafion various cu- rious phenomena not yet adverted to, befides thofe explained in the Sections on Dreams, Reveries, Ver- tigo, and Drunkennefs ; and may thus difturb the deductions of our reafonings, as well as the dreams of our imaginations ; prefent us with falfe degrees of fear, attach unfounded value to trivial circum- itances ; give occafion to our eaily prejudices and antipathies ; $14 PERIODS OF DISEASES. SECT. XXXVI. ,. antipathies; and thus embarrafs the happinefs of our lives. A copious and curious harveft might be reap, ed from this province of fcience, in which, howe- ver, I ihall not at prefent wield my fickle. SECT. XXXVI. OF THK PERIODS OF DISEASES. J. Mufcles excited by volition foon ceafe to contraB, ot by fenfation, or by irritation, owing to the exhauf* tjon of fenforial power. Mufcles fubjefled to /eft Jtimulus have tJieir fen fur ia/ power accumulated^ Hence the periods of fame fevers. Want of irrita- bility after intoxication. II. i. Natural afiions cate- nated with daily habits of Life, z . With folar periods. Periods of Jleep. Of evacuating the bowels. 3. Na- tural aftions. catenated* with lunar periods. Men- Jlr nation. Venereal or gafm of animals. Barrennefs. III. Periods of difeafed animal aclions from flated returns of no&urnal col-d, from folar and lunar in- fluence. Periods of diurnal fever, heQic fever , quo- tidian , tertian, quartan f ever. Periods of gout , fleurify, of fevers with arterial, debility, and with Arterial ftrength- Periods of rhaphania, of nervous cough, hemicrania, arteria( hemorrhages, hemorr- hoids, hcemoptoe, epilepfy, palfy, apoplexy, madnefs. IV. Critical days depend on limar periods. Lunar periods in the fmall po%. I. IF any of our mufcles be made to contract viqlently by the power pf volition, as ihofe of th$ fingers, SECT. XXXVI. i. PERIODS OF DISEASES. 515 lingers, when any one hangs by his hands on a iwing, fatigue foon enfu.es ; and the mufcl.es ccafe to act, owing to the temporary exhauftion of the fphit of animation ; as foon as this is again accu- mulated in the mufcles, they are ready to contract again by the efforts of volition. Thofe violent mufcular actions induced by pain become in the fame manner intermitted and recur- rent ; as in labour-pains, vomiting, tenefmus, ftran- gury ; owing likcwife to the temporary exhauftion of the fpirit of animation, as above mentioned. When any ftimulus continues long to act writh unnatural violence, fo as to produce too energetic action of any of our moving organs, thofe motions foon ceafe, though the flimulus continues to act; as in looking long on a bright object, as on an jnch-fquare of red filk laid on white paper in the jfunfhine. See Plate I. in Sect. IIL i. ' On the contrary, \vhere lefs of the flimulus of volition, fenfation, or imitation, have been ap- plied to a mufcle than ufual ; there appears to be an accumulation of the fpirit of animation in the jnoving organ ; by which it is liable to a£t with greater energy from lefs quantity of flimulus, than was previoufly neceflary to excite it into fo great action ; as after having been imrnerfed in fnow the cutaneous veffels of our hands are excited imp ilronger action by the flimulus of a lefs degree of heat, than would previously have produced that effea. From hence the periods of fome fever-fits may take their origin, either fimply, or by their acci- dental coincidence with lunar and folar r.^riofls, or with the diurnal periods of heat and cold, to be treated of below ; for during the cold fit at the commencement of a fever, from whatever caufe that cold fit may be induced, it follows, i. That the fpirit of animation muft become accumulated in the PERIODS OF DISEASES. SECT. XXXVl-a, the parts, which exert during this cold fit lefs than their natural quantity of adion. 2. If the caufe producing the cold fit does not increafe, or becomes Siminifhed ; the parts before benumbed or inadive become now excitable by fmaller ftimulus, and are thence thrown into more violent a6Uon than is na- tural; that is, a hot fitfucceeds the cold one. 3. By the energetic a6tion of the fyftem during the hot fit, if it continues long, an exhauftion of the fprit of animation takes place, and another cold fit is liable to fucceed, from the moving fyftem not being excitable into a&ion from its uiual ftimulus. This inirritability of the fyftem from a too great previous ftimulus, and confequent exhauftion of fenforial power, is the caufe of , the general debi- lity, and ficknefs, and head ach, fonie hours after intoxication. And hence we fee one of the caufes of the periods of fever-fits ; which however are fre- quently combined with the periods of our diurnal habits^ or of heat and cold, or of folar or lunar pe- riods. When befides the tendency to quiefcence occa- iioned by the expenditure of ienforial power during the hot fit of fever, fome other caufe of torpor, as the folar or lunar periods, is neceffary to the in- troduction of a fecond cold fit ; the fever becomes of the intermittent kind ; that is, there is atfpace of time intervenes between the end of the hot fit, and the commencement of the next cold one. But where BO exteriour caufe is neceflfary to the introduction of the fecond cold fit ; no fuch interval of health intervenes ; but the fecond cold fit commences, as foon as the fenforial power is fufficiently exhaufted by the hot fit ; and the fever becomes continual. II. i. The following are natural animal a&ions, •which are frequently catenated with our daily habits of life, as well as excited by their natural irritati- ons» The periods of hunger and thirft become catenated SECT. XXXVI. a. PERIODS OF DISEASES. 517 catenated \vith certain portions of time, or degrees of exhauftion, or other diurnal habits of life. And if the pain of hunger be not relieved by taking food at the ufual time, it is liable to ceafe till the next period of time or other habits recur , this is not only true in refpec~l to our general deiire of food, but the kinds of it alfo are governed by this periodical habit ; infomuch that beer taken to break- fail will diilurb the digeftion of thofe, who have been accuftomed to tea ; and tea taken at dinner will difagree with thofe, who have been accuftomed to beer. Whence it happens, that thofe, who have weak ftomachs, will be able to digeft more food, if they take their meals at regular hours; becaufe they have both the ftimulus of the aliment they take, and the periodical habit, to aflat their digeftion. The periods of emptying the bladder are not only dependent on the acrimony or diflention of the water in it, but are frequently catenated with ex- ternal cold applied to the ikin, as in cold bathing, or wafhing the hands ; or with other habits of life, as many are accuftomed to empty the bladder be- fore going to bed, or into the houfe after a journey, and this whether it be full or not. Our times of refpiration are not only governed by the ftimulus of the blood in the lungs, or our defire of frefh air, but alfo by our attention to the hourly objecls before us. Hence when a perfon is earneiily contemplating an idea of grief, he forgets to breathe, till the fenfation in his lungs becomes very urgent ; and then a figh fuccecds for the pur- pofe of more forcibly pufhing forwards the blood, which is accumulated in the lungs. Our times of refpiration are alfo frequently go- verned in part by our want of a fteady fupport for the a6lions of our arms, and hands, as in threading a needle, or hewing wood, or in fwimming; when we are intent upon thefe objefts, we breathe at the PERIODS OF DISEASES. SECT. XXXVI. a. «he intervals of the exertion of the petforal muf- ,cles. 2. The following natural animal a&ions are influ- enced by folar periods. The periods of fleep and of waking depend much on the folar period, for we are inclined to fleep at a certain hour, and to awake at a certain hour, whether we have had more or lefs fatigue during the day, if within certain limits ; and are liable to wake at a certain hour, whether we went to bed earlier or later, within certain li- mits. Hence it appears, that thofe who complain of want of fleep, will be liable to fleep better or longer, if they accuftom themfeives to go to reft, and to rife, at certain hours. The periods of evacuating the bowels are gene- rally connected with feme part of the folar day, as well as with the acrimony or diftenlion occafioned by the feces. Hence one method of corre&ing cof- tivenefs is by endeavouring to eftablifli a habit of evacuation at a certain hour of ,the day, as recom- mended by Mr. Locke, which may be accomplifhed by ufing daily voluntary efforts at thofe times, join- ed with the ufual flimulus of the material to be eva- cuated. 3. The following natural animal actions are con- netted with lunar periods, i. The periods of fe- male menftruation are connected with lunar periods to great exaclnefs, in fome inftances even to a few hours. Thefe do not commence or terminate at the full or change, or at any other particular part of the lunation, but after they have commenced at any part of it, they continue to recur at that part with great regularity, unlefs difturbed by fome violent circumftance, as explained in Se&. XXXII. No. 6.^ their return is immediately caufed by deficient ve- nous abforption, which is owing to the want of the flimulus, ciefigned by nature, of amatorial copula- tion, or of the growing fetus. When the catamenia returns SacT. XXXVI. 3. PERIODS OF DISEASES. 5*9 returns fooner than the period of lunation, it fhews a tendency of the conftitution to inirritability ; that is, to debility, or deficiency of fenforial power, and is to be relieved by fmali dofes of fleet and opium. The venereal oigafm of birds and quadrupeds feems to commence, or return about the moft pow- erful luna-tions at the vernal OF autumnal equinoxes; but if it be difappointed of its object, it is faid to recur at monthly periods; in this refpect refembling the female catamenia. Whence it is believed, that women are more liable to become pregnant at or about the time of their catamenia, than at the in- termediate times ; and on this account they are fel- dom much mrftaken in their reckoning of nine lunar periods from the laft menftruation ; the inattention to this may fometimes have been the caufe of fup- pofed barrennefs, and is therefore worth the Obfer- vauon of thofe, who wifli to have children. III. We now come to. the periods of difeafed ani- mal actions. The periods of fever-fits, which de- pend on the dated returns of no&urnal cold, are difcufled in Sect. XXXII. 3. Thole, which originate or recur at folar or lunar peiiods, are alfo explain- ed in Section XXXII. 6. Thefe we (hall here enu- merate ; obferving, however, that it is not more fur- prifing, that the influence of the varying attradlions of the fun and moon, mould raife the ocean into mountains, than that -it fhould affect the nice fenfi- bilities of animal bodies ; though the manner of its operation on them is difficult to be underftood. It is probable however, that as this influence gradually leflens during the courfe of the day, or of the luna- tion, or of the year, fome actions of our fyftem be- come lefs and lefs ; till at length a total quiefcence of fome part is induced ; which is the commencement of the paroxyfms of fever, of menftruation, of pain \\ith decreafed action of the affected organ, and of confequent convulfion, I. A PERIODS OF DISEASES. SECT. XXXVI. 5, 1. A diurnal fever in fome weak people is diftinft- !y obferved to come on towards evening, and to ceafe with a moift (kin early in the morning, obey- ing the folar periods. Perfons of weak conftituti- ons aie liable to get into better fpirits at the accefs of the hot fit of this evening fever; and are thence inclined to fit up late ; which by further enfeebling them increafes the difeafe ; whence they lofe their ftrength and their colour. 2. The periods of hectic fever, fuppofed to arife from abforptionof matter, obeys the diurnal periods like the above, having the exacerbefcence towards evening, and its remifiion early in the morning, with fweats, or diarrhoea, or urine with white fediment. 3. The periods of quotidian fever are either cate- nated with folar time, and return at the intervals of twenty-four hours ; or with lunar time, recurring at the intervals of about twenty-five hours. There is great ufe in knowing with what circumftances the periodical return or new morbid motions are con- joined, as the moil effectual times of exhibiting the proper medicines are thus determined. So if the torpor, which ufhers in an ague fit, is catenated with the lunar day : it is known, when the bark or opium mud be given, fo as to exert its principal effect about the time of the expected return. Solid opium mould be given about an hour before the expected cold fit ; liquid opium and wine about half an hour ; the bark repeatedly for fix or eight hours previous to the expected return. 4. The periods of tertian fevers, reckoned from the commencement of one cold fit to the commence- ment of the next cold fit, recur with folar intervals of forty-eight hours, or with lunar ones of about fifty hours. When thefe of recurrence begin one or two hours earlier than the folar period, it (hews, that the torpor or cold fit is produced by lefs ex- ternal influence ; and therefore that it is more liable to SECT. XXXVI. 3. PERIODS OF DISEASES. 521 to degenerate into a fever with only remiffions ; fo when menftruation recurs fooner than the period of lunation, it (hews a tendency of the habit to torpor or inirritability. 5* The periods of quartan fevers return at folar intervals of feventy-two hours, or at lunar ones of about feventy-four hours and an half. This kind of ague appears mod in moid cold autumns, and in cold countries replete with marfhes. It is attended with greater debility, and its cold accefs more dif- ficult to prevent. For where there is previoufly a deficiency of fenforial power, the conftitution is liable to run into greater torpor from any further diminution of it ; two ounces of bark and fome fteel fhould be given on the day before the retutn of the cold paroxyfm, and a pint of wine by de- grees a few hours before its return, and thirty drops of laudanum one hour before the expected cold fit. 6. The periods of the gout generally commence about an hour before fun-rife, which is ufually the coldeft part of the twenty-four hours. The greater periods of the gout fee in alfo to obferve the folar influence, returning about the fame feafon of the year. 7. The periods of the pleurify recur with exacer- bation of the pain and fever about fun-fet, at which time venefeclion is of moft fervice. The fame may be obferved of the inflammatory rheumatifm, and other fevers with arterial ftrength, which feem to obey folar periods ; and thofe with debility feem to obey lunar ones. 8. The periods of fevers with arterial debility feem to obey the lunar day, having their accefs daily nearly an hour later ; and have fometimes two ac- cefles in a day, refembling the lunar efJe&s upon the tides. 9. The periods of rhaphania, or convulfions of the limbs from rheumatic pains, feem to be con- $si PERIODS OF DISEASES. SECT, xxxvr. £ fie&ed with fblar influence, returning at nearly the fame hour for weeks together, unlefs difturbed by the exhibition of powerful dofes of opium. So the periods of Tuflis ferina, or viokrit cough with flow pulfe, called nervou's cough, recurs by fo- lar periods. Five grains of opium given at the time the cough commenced di fturbed the period, from feven in the evening to eleven, at which time it re- gularly returned for fome days, during 'which time the opium was gradually omitted. Then 120 drops of laudanum were given an hour before the accefs of the cough, and it totally ceafed. The laudanum was continued a fortnight, and then gradually dif- continued. 10. The periods: of herrricranra, and of painful epilepfy, are liable to obey lunar periods, both in; their diurnal returns, and in their greater periods of •weeks, but are a4fo induced by other exciting caufes, ir. The periods of arterial haemorrhages feem ta return at folar periods about the fame hour of the evening or morning. Perhaps the venous haemorr- hages obey the lunar periods, as the catamenia, and haemorrhoids. 12. The periods of the haemorrhoids, or piles, in fome fecur monthly, in others only at the greater lunar influence about the equinoxes. 13-. The periods of hsemoptoe fomefimes obey folar influence, recurring early in the morning for feveral days; and fomettmes lanar periods, recur- ring monthly ; and fometimes depend on our hours of fleep.' See Clafs I. 2, i. 9. 14. Many of the fifft periods of epileprtic fits obey the monthly lunation with fome degree of accuracy; others recur only at the mod powerful lunations before the vernal equinox, and after the autumnal one ; but when the conftitution has gained a habit of SEC*. XXXVt. 4. ^ERIOtfS OF DISEASES. 523 of relieving difagreeable fenfations by this kind of exertion, the fit recurs from any flight caufe. 15. The attack of the palfy and apoplexy are known to recur with great frequency about the equi- noxes. 1 6. There are numerous inflances of the effect of the lunations upon the periods of infamty, whence the name of lunatic has been given to thdfe afflicted with this difeafe. IV. The critical days, in which fevers are fup- pofed to terminate, have employed the attention of medical philofophefs from the days of Hippocrates to the prefent time. In whatever part of a lunation a fever commences, which owes either its whole caufe to folar and lunar influence, or to this in conjunction with other caufes ; it would feem, that the effect would be the greateft at the full and new moon, as the tides rife higheft at thofe times, and tvould be the leaft at the quadratures ; thus if a fever- fit fhould commence at the new or full moon, occafioned by the folar and lunar attraction dimi- nifhing fome chemical affinity of the particles of blood, and thence decfeafing their ftimulus on our fanguifefous fyftem, as mentioned in Sect. XXXIL 6. this effect will daily decreafe for the firft feven days, and will then increafe till about the fourteenth day, and will again decreafe till about the twenty- firlt day, and increafe again till the end of the lu- nation. If a fever-fit from the above caufe fhould commence on the feventh day after either lunation, the reverfe of the above circumftances would hap-* pen. Now it is probable, that thofe fevers, whofe crifis of terminations are influenced by lunations, may begin at one or other of the above times, namely at the changes or quadratures ; though fuf- ficient obfervations have not been made to afcer- tain this circumftanee. Hence I conclude* that the fmall-pox and mealies have their critical days, not VOL. I. Mm governed KRIODS OF DISEASES SECT. XXXVI. 4, governed by the times required for certain chemical changes in the blood, which affect or alter the fti- mulus of the contagious matter, but from the daily increafing or decreafing effect of this lunar link of catenation, as explained in Section XVII. 3. 3. And as other fevers terminate moil frequently about the feventh, fourteenth, twenty-firft, or about the end of four weeks, when no medical afliftance has dif- turbed their periods, I conclude, that thefe crifes, or terminations, are governed by periods of the lu- nations, though we are ftill ignorant of their manner of operation. In the diflinft fmall-pox the veftiges of lunation are very apparent, after inoculation a quarter of a lunation precedes the commencement of the fever, another quarter terminates with the complete erup- tion, another quarter with the complete maturation,, and another quarter terminates the complete abforp~ tion of a material now rendered inoffenfive to the confiitution* SECT, . XXXViL i DIGESTION, SECRETION, £c. SECT. XXXVII. OF DIGESTION, SEC&ETtdtf, j. Cryflals increase by the greater attraction of their jutes. Accretion by chemical precipitations, by weld- ing, by preffure, by agglutination. II. Hunger, di- gejlion, why it cannot be imitated out of the body. Lacleals abforb by animal feleflion, or appetency. III. The glands and pores abforb nutritious particles by an ima I feleflio n . Organ ic p a r tides of Buffon . Nu- trition applied at the time of elongation of fbres. Like inflammation. IV. // feems eafier to have pre- ferred animals than to reproduce them.. Old age and death from, inirr liability. Three caufes of this. Ori- ginal fibres of the organs of fenfe and mufcles un- changed. - V. Art of producing long life. I. -THE larger cryftals of faline bodies may be Conceived to arife from the combination of fmaller Cryftals of the fame form, owing to the greater at- tractions of their fides than of their angte. Thus if four cubes were floating in a fluid, whofe friction or refinance is nothing, it is certain the fides, of thefe cubes would attract each other ftronger than their angles; and hence that thefe four fmaller cubes would fo arrange themfelves as to produce one larger one. There are other means of chemical accretion, fuch as the depofitions of diflblved calcareous or filiceous particles, as are feen in the formation of the ftala&ites of limeftone in Derbyfhire, or of cal- M m 2 ccdone S*6 DIGESTION, SECRETION, &c. SECT. XXXVII. *, cedonc in Cornwall. Other means of adhefion ace produced by heat and preffure, as in the welding. of iron bars ; and other means by fimple preffure, as in forcing two pieces of caoutchou, or elaftic gum, to adhere ; and lafrly, by the agglutination of a third fubftance penetrating the pores of the other two, as in the agglutination of wood by means of animal gluten. Though the ultimate particles of animal bodies are held together during life, as welt as after death, by their J'pecifie attraction of cohe- fion, like ail other matter; yet it does not appear, that their original organization was produced by chemical laws, and their production and-« increafe muft therefore only be looked for from the laws of animation. II. When the pain of hunger requires relief, cer- tain parts of the material world, which furround; us, when applied to our palates, excite into action the mufcles of deglutition ; and the material is fwallowed into the ftamach. Here the new aliment becomes mixed with certain animal fluids, and un- dergoes & chemical procefs, termed digeftion; which however eherniftry has not yet learnt to imitate out of the bodies of living animals or vegetables. This procefs feems very fimilar to the facchasine proeefs in the lobes of farinaceous feeds, as of barley, when it begins to germinate; except that, along with the fugar, oil and mucilage are alfo produced; which form the chyle of animals, which is very fimilar to their milk. The reafon, I imagine, why tBis chyle -making, or faccharine proeefs, has not yet been imitated by chemical operations, is owing to the materials be- ing in fuch a fituation in refpect to warmth, moif- ture, and motion ; that they will immediately change into the vinous or acetous fermentation ; except the new fugar be abforbed by the numerous lac- teal »ECT. xxxvii. 3. DIGESTION; SECRETION, &c. 527 teal or lymphatic vefiels, as foon as it is produced .; which is not eafy to imitate in the laboratory. Thefc ladeal veffels have mouths, which are ir- ritated into aflion by the ftimuliis of the fluid, which fur rounds them ; and t>y animal feledion, or appetency, they abforb fucli part of the fluid as is agreeable to their palate ; thofe parts, for in- ftance, wljich are already converted into chyle, be- fore they have time to undergo another change by a vinous or acetous fermentation. This animal ab- forption of fluid is almoft vifible to the naked eye in the a&ion of the pun6la lacrymalia ; which im- bibe the tears from the eye, and difcharge them again into ihe noftrils. III. The arteries conftitute another refervoir of a changeful fluid; from which, after its recent oxy- genation in the lungs, a further animal feleclion of various fluids is abforbed by the numerous glands ; thefe fek(S their refpe&ive fluids from the blood, which is perpetually undergoing a chemical change ; but the fele&ion by thefe glands, like that of the ladleals, which open their mouths into the digefting aliment in the ftomach, is from animal appetency, not from chemical affinity ; fecretion cannot there- fore be imitated in the laboratory, as it con lifts in a fele&ion of part of a fluid during the cheiiiical change of that fluid. The mouths of th£ la&eals, and lymphatics, and the ultimate terminations of the glands, are finer than can eafily be .conceived ; yet it is probable, that the pores, jpr imerllices of ihe parts^ or coats^ which conftitute thefe ultimate veffels, may ftill have greater tenuity ; and that thefe pores from the above analogy mu ft poffefs a fimilar power of irritability, and abforb by their living energy the particles of fluid adapted to their purpofes, whether to replace the parts abraded or diffolved, or to elongate and enlarge themfelves. Not only every kind p8 DIGESTION, SECRETION, &c. SECT. XXXVII. 3. kind of gland is thus endued with its peculiar ap- petency, and felects the material agreeable to its tafte from the blood, but every individual pore ac- quires by animal fele&ion the material, which it wants ; and thus putrition feems to be performed in a manner To fimilar tbfecretion, that they only dif- fer in the one retaining, and the other parting again with the particles, which they have {elected from the blood. This way of accounting for nutrition from fti- mulus, and the confequent animal feledtion of par- ticles, is much more analogous to other phenomena of the animal microcofm, than by having recourfe to the mierofcopic ariimalcula, or organic particle? of Buffon andNeedham ; which being already com- pounded muft themfelves require nutritive particles to continue their own exiftence. ' And muft be liable to undergo a change by our digeftive or fe- cretory organs ; otherwife mankind would foon re- femble by their theory the animals, which they feed upon. He, who is nourifhed by beef or ve- nifon, would in time become horned ; and he, who feeds on pork or bacon, would gain a nofe proper for rooting into the earth, as well as for the percep- tion of odours, The whole animal fyftem may be confidered as confiding of the extremities of the nerves, or as having been produced from them ; if we except perhaps the medullary part of the brain redding in the head and fpine, and in the trunks of jhe nerves. Thefe extremities of the nerves are either of thofe of locomotion, which aVe termed mufcular fibres; or of thofe of fenfation, which confti tut e the im- inediate organs of fenfe, and which have alfo their peculiar motions. Now as the fibres, which con- ftitute the bones and membranes, poflefs originally fenfation and motion ; and are liable again to pof- fefs them, when tliey become inflamed ; it follows, that M. XXXVIf. 3. DIGESTION, SECRETION, &c. 529 that thofe were, when fir ft formed, appendages to the nerves of fenfation or locomotion, or were form- ed from them. And that hence all thefe folid parts of the body, as they have originally confifted of extremities of nerves, require an apportion of nu- tritive particles of a fimilar kind, contrary to the opinion of Buffon and Needham above recited. Laftly, as all thefe filaments have poffefTed, or do poffefs, the power of contra&ion, and of confe- quent inertion or elongation ; it feems probable, that the nutritive particles are applied during their times of elongation ; when their original conftitu- ent particles are removed to a greater diftance from each other. For each mufeular or fenfual fibre may be coniidered as a row or firing of beads ; which approach, when in contraction, and recede during its reft or elongation ; and our daily expe- rience fhews us, that great action emaciates the fyf- tem, and that it is repaired during reft. Something like this is feen out of the body; for if a hair, or a fingle untwifted fibre of flax or {ilk, be foaked in water ; it becomes longer and thicker by the water, which is abforbed into its pores. Now if a hair could be fuppofed to be thus immerfed in a folution of particles fimilar to thofe, which compofe it ; one may imagine, that it might be thus increafed in weight and magnitude ; as the par- ticles of oak- bark increafe the fubftance of the hides of beafts in the procefs of making leather. I men- tion theft not as philofophic analogies, but as fi- miles to facilitate our ideas, how an accretion of parts may be effected by animal appetences, or fe- ie&ions, in a manner fomewhat fimilar to mechani- cal or chemical attractions. If thole new particles of matter, previoufly pre- pared by digeflion and fanguification, only fupply the places of thofe, which have been abraded by the actions of die fyftem, it is properly termed nu- trition. DIGESTION, SECRETION, &c. SECT, XXXVII. 4. trition. If they arc applied to the extremities qf the nervous fibrils, or in fuch quantity as to in:- creafe the length or praifitude of them, the body becomes at the fame time enlarged, and its growth is Jncreafed, as well as its deficiencies repaired. Jr* this laft cafe fqmething more than a fimple. apportion or feleftion of particles feems to be ne- cefTary ; as many parts of the fyflem during its growth are caufect to recede from thofe, with which they were before in contact ; as the ends of the bones, or cartilages, recede from each other, as their growth advances: this procefs refembles in- flammation, as appears in ophthalmy, or in the production of new flefh in ulcers, where old veffels are enlarged, and new ones produced ; and like that is attended with fenfation. In this fuuation the veffels become diixcnded with blood, and acquire greater fenfibility, and may thus be compared to the erection of the penis, or of the nipples of the breads of women ; while new particles become added at the fame time; as in the procefs of nutrition above defcribed. When only the natural growth of the various parts of the Ipody is produced, a pleafurable fenfa- tion Attends it, as in -youth, and perhaps in thofe, who are in the progrefs of becoming fat. When an unnatural growth is the confequence, as in in- flammatory difeafes, a painful fenfation attends the enlargement of the fyftem. IV. This appofition of new parts, a,s the old ones difappear, felefted from the aliment we talce, firft enlarges and flrengtheris our bodies for twenty years, for another twenty years it keeps us in health and vigour, and adds ftrength knd folidity to the iyftem ; and then gradually ceafes to nourifli us pro- perly, and for another twenty years we gradually link into decay, and finally ceafe to act, and tot exifL On SECT. XXXVII. 4. DIGESTION, SECRETION, &c. $31 On confidering this fubject one ftiould have ima- gined at firfl view, that it might have been eafier for nature to have fupportcd her progeny for ever in health and life, than to have perpetually repro- duced them by the wonderful and myfterious pro- cefs of generation. But it feems our bodies by long habit ceafe to obey the ftimulus of the aliment, which fhould fupport us. After we have acquired our height and folidity we make no more new parts, and the fyftem obeys the irritations, fenfati- ons, volitions, and aflbciations, with lefs and lefs energy, till the whole finks into inaction. Three caufes may confpire to render our nerves lefs excitable, which have been already mentioneres; whence the blood of rifh receives oxygene from the water, or from the air it contains, by means of their gills, in the fame manner as the blood is oxygenated in the lungs of air-breathing animals; it changes its colour at the fame time from a dark to a light red in the vefTels of their gills, which- constitute a. pulmonary organ adapted TO the medium in which they live. Thirdly, that the placenta- confifts of arteries carrying the blood to its extremities, and a vein bringing it back, rc- fembling exactly in ftru£ture the lungs and gills above mentioned ; and that the blood changes ife colour from a dark to a light red in palling through thefe veifels. This! analogy between the lungs and gills of ani- mals', and the placenta of the fetus, extends through a great variety of other circumflances ; thus air- breathing creatures and fifh can live but a few mr- nutes without air or water ; or when they are con- fined in fuch air or water, as has been fpoiled by rheir own refpiration ; the fame happens to the fetus, which, as foon as the placenta is feparated from the uterus, muft either expand its lungs, and receive air, or die. Hence from the ftructure, as well as the ufe of tire placema, it appears to be a refpiratory organ, like the gills of fifh, by which the blood in the fetus becomes oxygenated. From the terminations of the placemal veffels not being obferved to bleed after being torn from the uterus, while thofe of the uterus effufe a great quan- tity of florid arterial blood, the terminations of the plaeental veffels would feem to be inferted into the arterial ones of the mother 5 and to receive- oxyge- natioa 2. OXYGEN ATION OF BLOOTJ. $37 nation from the pafling currents of her blood through their coats or membranes ; which oxyge- nation is proved by the change of the colour of the blood irom dark to light red in its paifage from the placental arteries to the placental vein. The curious ftrudure of the cavities or lacunas of the placenta, demonftrated by Mr. J. Hunter, explain this eircumftance. That ingenious philofo* pher has fliewn, that there are numerous cavities or lacunae formed on that iide of the placenta, which is in contact with the uterus ; thofe cavities or cells are filled with blood from the maternal arte- ries, which open into them ; which blood is again taken up by the maternal veins, and is thus per- petually changed. While the terminations of the placental arteries and veins are fpread in tine reticu- lation on the fides of thefe cells. And thus, as the growing fetus requires greater oxygenation, an ap- paratus is produced refembling exactly the air-cells of the lungs. In cows, and other ruminating animals, the in- ternal furface of the uterus is unequal like hollow cups, which have been called cotyledons ; and into thefe cavities the prominencies of the numerous pla- centas, with which the fetus of thofe animals is furnifhed, are inferted, and ftrictly adhere ; though they may be extracted without efFufion of blood. Thefe inequalities of the uterus, and the numerous placentas in confequence, feern to be defigned for the purpofe of expanding a greater furface for the terminations of the placental veflels for the purpofe of receiving oxygenation from the uterine ones; as the progeny of this clafs of animals are more com- pletely formed before their nativity, than that of the carnivorous clafles, and muft thence in the lat- ter weeks of pregnancy require greater oxygenation. Thus calves and lambs can walk about in a few minutes #3 OXYGENATIOtt OF BLOOD. SECT. XXXVIIX. $. minutes after their birth ; while puppies and kittens remain many days without opening their eyes. And though on the reparation of the cotyledons of ru- minating animals no blood is effufed, yet this is owing clearly to the greater power of con trad ion of their uterine lacunas or alveoli. See Medical Mays, Vol. V, page 144. And from the fame caufe they are not liable to a fangurfer^us menftruation. The neceffity of the oxygenation of the blood in the fetus is farther illuflrated by the analogy of the chick in the egg ; which appears to have its blood oxygenated at the extremities of the veffels fur- rounding the yolk j which are fpread on the air-bag at the broad end of the egg, and may abforb oxy- gene through that moift membrane from the air confined behind it ; and which is fhewn by experi- ments in- the exhaufled receiver to be changeable though the (hell. This analogy may eve^n be extended to the grow- ing feeds of vegetables ; which were fhewn by Mr. Scheele tor require a renovation of the air over the water, in w'hicb they were confined. Many vege- table feeds are furrounded with air in their pods or receptacles, as peas, the fruit of ftaphylea, and lich- nis veficaria1 ; but it is probable* that thofe feeds, after they are fried, as well as the fpawn of fifh, by the fituation of the former on or near the moid and aerated furface of the earth, and of the latter in the ever-changing and ventilated water, may not be in need of an apparatus for the oxygenation of their firft blood, before the leaves of one, and the gill* of the other, are produced for this purpofe* III. j. There .are many arguments, befides tfie ltri& analogy between the liquor amnii and the albumen ovi, which mew the former to be a nutri- tive fluid ; and that the fetus in the latter months ef pregnancy takes it into its ftomach j and that in SECT. XXX VIII. 3. OXYGEN ATION OF BLOOD. 539 In confequence the placenta is produced for fome other important purpofe. Firft, that the liquor amnii is riot an excrementi- tious fluid is evinced, becaufe it is found in greater quantity, when the fetus is young, decreafmg after a certain period till birth. Haller alTerts, " that in fome animals but a frriall quantity of this fluid lemains at the birth. In the eggs of hens it is confumed on the eighteenth day, fo that at the ex- clufion of the chick fcarcely any remains. In rab- bits before birth there is none." Elern. Phyfiol. Had this been an excrerrientitious fluid, the contrary would probably have occurred. Secondly, the fkin of the fetus is covered with a whitifh cruft or pel- licle, which would feem to preclude any idea of the liquor amnii being produced by any exfudation of perfpirable matter. And it camiot confift of urine, becaufe in brute animals the urachus pafles from the bladder to the alantois for the exprefs purpofe of carrying off that fluid ; which however in the human fetus feems to be retained in the diftended bladder, as the feces are accumulated in the bowels of all animals. i. The nutritious quality of the liquid, which furrounds the fetus, appears from the following con- fiderations. I. It is coagulable by heat, by nitrous acid, and by fpirit of wine, like milk, ferum of blood, and other fluids, which daily experience evinces to be nutritious. 2. It has a faltifh tafte according to the accurate Baron Haller, not unlike the whey of milk, which it even referable* in fmell. 3. The white -of the egg which conftitutes the food of the chick, is fhewn to be nutriiious by our daily expe- rience ; befides the experiment of its nutritidus ef- fects mentioned by Dr. Fordyce in his late Treatife on Digeftion, p. 178; who adds, that it much re- fembles the eflential parts of the ferum of blood. VOL. I. Nn 3. A 540 OXYGENATION OF BLOOD. SF.CT. XXXVIII. 3. 3. A fluid iimilar to the fluid, with which the fetus is funounded, except what little change may be produced by a beginning digeftion, is found in, the flomach of the f<:tus; and the white of the egg is found in the fame manner in the llomach of the chick. Numerous hairs, fimilar to thofe of its fkin, are perpetually found among the contents of the (to* mach in new-bom calves ; which mufl therefore have licked themfelves before their nativity. Blalii Anatom. See SedL-XVl. 2. on Inftincl, The chick in the egg is feen gently to move in its furrounding fluid, and to open and Onit its mouth alternately. The fame has been obferved in puppies. Bailer's El. Phyf. I. 3. p. 201. A column of ice has been feen to reach down the cefophagus from the mouth to the ftomach in a fro- #en fetus ; and this ice was the liquor amnii frozen. The meconium, or firft faeces, in the bowels of new-born infants evince, that fomething has been digefted ; and what could this be but the liquor amnii together with the recrements of the gaftric juice and gall, which were neceflary for its digef- tion ? There have been recorded fome monftrous births of animals without heads, and confequently without mouths, which feem to have been delivered on doubtful authority, or from inaccurate obfervation. There are two of fuch monflrous productions how- ever better attefted ; one of a human fetus, menti- oned by Gipfon in the Scots Medical EfTays ; which having the gula impervious was furnifhed with an aperture into the wind-pipe, which communicated below into the gullet ; by means of which the liquor amnii might be taken into the ftomach before nati- vity without danger of fuffocation, while the fetus had no occalion to breathe. The other monftrous fetus is defcribed by Vander Wiel, who afferts, that he SECT. XXXVIII.*. OXYGENATION OF BLOOD. $41 he faw a monftrous lamb, which had no mouth, but initead of it was furnifhed with an opening in the lower part of the neck into the ftomach. Both thefe inftances evidently favour the do&rine of the fetus being nouriilied by the mouth ; as otherwife there had b^en no neceflity for new or unnatural apertures into the flomach, when the natural ones were deficient. From thefe facls and obfervations we may fafely infer, that the fetus in the womb is nourifhed by the fluid which furrounds it; which during the firft period of geftation is abforbed by the naked lac- teals ; and is afterwards fvvallowed into the ftomach and bowels, when thefe organs are perfected ; and laftly that the placenta is an organ for the purpofe of giving due oxygenation to the blood of the fetus ; which is more neceffary, or at lead more frequently neceflfary, than even the fupply of food. The queltion of the great Harvey becomes thus eafily anfwered. es nciv in it abilities, and fenfilnlities with new or- ganizations, as in wnmded f nails, polypi, moths, gna's, tad- poles. Hence new parts are acquired by addition not by dif+ tcntir.n 3. All parts of the body giow if not confined. 4. Faujes deficient at their extremities, or have a auplicaturs of parts. Monfiious bi>th*. Double parts of vegetables. 5. Afulfs cannot be formed by diftention of ttit feminal ens. 6. Families of animals ft om a mixture of their orders. Mules impcrfeft. 7. Animal appetency like chemical affinity. Vis fabricatrix and mcdicatrix of nature. 8. 'I he changes of ani- mah before and after nativity. Similarity ef their Jlruclure. Changes in them from luft, hunger, and danger. All warm- blooded animals derived from one living filament. Cold-blooded animals, infefls, worms, vegetables, derived alfo from one living fibmtnt. A'fale animals have teats. Male pigeon gives milk The world iff elf generated. The caufe of caufcs. A ftate of probation and rcfpon fib dity. V. I. Efficient cauje of the colours of birds eggs, and of hair and feathers, which become white in fnoivy countries. Imagination of the female colours tie egg Ideas or motions of the retina imitated by the extremities of the nerves of touch, or rete mucofum. 2. Nu- triment fupplied by the female of three kinds. Her imagina- tion can only affefl the fir Jl kind. Mules how produced, and mulattocs. Organs of reproduction why deficient in mules. Eggs with double yolks. VI. I. Parlous fecretisns produced by the extremities of the veffels, as in tJie glands. Contagious matter. Atfany glands affetted by plcafurable ideas, as thofe ichich fecreie the Jemcn 2. Snails and worms are herma- phrodite, yet cannot impregnate themfelves. Final caufe of this. 3. The imagination of th$ male forms ifa fex. Ideas > or motions of the nerves of vifwn or of touch, are imitated by the ultimate etch emitie$ of the glands of the tejies, which mark the fex. This effefl of the imagination belongs only to the male. The fex of the embryon is not owing to accident. 4. •C.aufes of the changes it$ animals from imagination as in mon- fiers. Frem the male. From the female. 5. Mifcarriages. from fear. §. Power of the imagination of the male over the colour, form, and fex of the progeny. An injlance of. 7. Aft of generation accompanied with ideas of the male or . fcmalejotm. Art of begetting beautiful children of either fex. VII. Recapitulation. Vlil. Conclujion. Of caufe and ef- fect. The atomic phi'ofophy leads to a fir ft caufe. I. THE ingenious Dr. Hartley in his work on ail;, and ibme other philofophers, have been of opinion $44 GENERATION. SECT. XXXIX. i, opinion, that our immortal part acquires during this life certain habits of action or of fentiment, which become for ever indiffoluble, continuing after death in a future ftate of exiftence j and add, that if thefe habits are of the malevolent kind, they muft ren- der the porTeflbr miferable even in heaven. I would apply this ingenious idea to the ^generation or pro- duction of the embryon, or new animal, which par- takes fo much of the form and propenfities of the parent. Owing to the imperfection of language the off- spring is termed a new animal, but is in truth a branch or elongation of the parent ; fmce a part of the embryon-animal is, or was, a part of the par rent; and therefoie in ftiicl: language it cannot be faid to be entirely new at the time of its produc- tion; and therefoie it may' retain fome of the habits of the parent-fyilem. At the earlieft period of its exiftence the embryon, as fecreted from the blood of the male, would feem to confift of a living filament with certain capabi- lities of irritation, fenfation, volition, and aflbciati- on ; and alfo with fome acquired habits or propenfi- ties peculiar to the parent : the former of theie are in common with other animals ; the latter feem to diftinguifh or produce the kind of animal, whether man or quadruped, with the fimilarity of feature or form to the parent. It is difficult to be conceiv- ed, that a living entity can be feparated or produced from the blood by the action of a gland ; and which fhall afterwards become an animal iimilar to that in, \vhofe velfels it is formed ; even though we mould fuppofe with fome modern theories, that the blood is alive ; yet every other hypothecs concerning ge- neration refts on principles dill more difficult to our comprehenlion. At the time of procreation this fpeck of entity h received into an appropriated nidus, in which it mufl i, GENERATION. 54$ mud acquire two circumftances neceffary to its life and growth ; one of thefe is food or fuftenance, which is to be received by the abforberit mouths of its veffels ; and the other is that pait of atmolphe- rical air, or of water, which by the new chemiliry is termed oxygene, and which affecls the blood by pafiing through the coats of the veffels which con- tain it. The, fluid furrounding the embryon in its new habitation, which is called liquor amnii, fup- plies it with nourilhment ; and as feme air cannot but be introduced into the uterus along with a new embryon, it would feem that this fame fluid would for a fhort time, fuppofe for a tew hours, fupply likewife a iufficient quantity of the oxygene for its immediate exiftence. On this account the vegetable impregnation of aquatic plants is performed in the air; and it is probable that the honey-cup or ne&ary of vegetables requires to be open to the air, that the anthers and ftigmas of the flower may have food of a more oxygenated kind than the common vegetable fap- juice. On the in'roduclion of this primordium of en- tity into the uterus, the irritation of the liquor amnii, which fui rounds it, excites the abibrbent mouths of the new veffels into action ; they drink up a part of it, and a pleafurable fenfation accompanies this new adtion ; at the fame time the chemical affinity of the oxygene acts through the veffels of the ru* befcent blood ; and a previous want, or difagreeable fenfaiion, is relieved by this procefs. As the want of this oxygenation of the blood is perpetual, (as appears from the inceffant neceffity of breathing by lungs or gills,) the veffels become extended by the efforts of pain or defne to feek this neceffary object of oxygenation, and to remove the difagreeable fenfation, which that want occafi- ons. At the fame time new panicles of matter are abforbed GENERATION. SECT. XXXtX. r. abforbed, or applied to thefe extended veffels, and they become permanently elongated, as the fluid in. cPnta& with them foon lofes the oxygenous part, which it at firft pofTeffed, which was owing to the introduction of air along with the embryon. Thefe new blood-veifels approach the fides of the uterus, and penetrate with their fine terminations into the veflelsof the mother; or adhere to them, acquiring oxygene through their coats from the paffmg cur- rents of the arterial blood of the mother. See SedU xxxyiii. 2. This attachment of the placenta! veffels to the irj* ternal fide of the uterus by their own proper efforts appears furthe.r illuflrated by the many inftances of extra-uterine fetufes, which have thus attached or infer ted tneir veflels into the peritoneum; or on the vifcera, exadUy in the fame manner as they na-* turally infert or attach them to the uterus. The abforbent veflels of the embryon continue to drink up nourifhment from the fluid in which they fvvim, or liquor amnii ; and which at firft needs no previous digeftive preparation ; but which, when the whole apparatus of digeftion becomes complete, is fwallowed by the mouth into the ftomach, and be- ing mixed with faliva, gaftric juice, bile, pancrea- tic juice, and mucus of the interlines, Becomes di* gefted, and leaves % recrement, which produces the firft feces of the infant, called mecpnjum. The liquor amnii is fecreted into the uterus, as the fetus requires it, and may proba^y be produced by the irritation of the fetus as an extraneous body ; fince a fimilar fluid h acquired from the peritoneum in cafes of extra-uterine geftatipn. 'The young ca- terpillars of the gadfly 'placed in the fkins of cows, 3nd the young of the ichneumon-fly placed in the backs of the caterpillars on cabbages, feem to pro- duce their nourifhment by their irritating the fides of their nidus. A vegetable fecretion and concre- tion is thus produced on oak-leaves by the gall- infedl, SECT, XXXIX. i. GENERATION. 54? infeft, and by the cynips in the bedeguar of the role; and by the young giafshopper on many plants, by which the animal luirounds itfelf with froth. But in no circumllance is extra-uterine geilation fo cxa&ly refembled as by the eggs of a fly, which are depofited in the frontal finus of flieep and calves. Thefe eggs float in fome ounces of fluid collected in a thin pellicle or hydatide. This bag of fluid comprefles the optic nerve on one licje, by which the vifion being lefs diiHncl in that eye, the animal lurns in perpetual circles towards the fide affecled, in order to get a more accurate view of objecls ; for the fame reafon as in fquinting the affected eye is turned away from the object contemplated. Sheep in the warm months keep their nofes clofe to the ground to prevent this fly from fo readily getting into their noftrils. The liquor amnii is fecrcted into the womb as it is required, not only in refpcdl to quantity, but, as the digcftive ppwers of the fetus become formed, this jfluid becomes of a different confidence and quality, till it is exchanged for milk after nativity. Haller- Phyfiol. V. i. In the egg the white part, which js analogous to the liquor amnii of quadrupeds, cpniifls of two jdiftincl: parts ; one of which is more vifcid, and probably more difficult of digeftion, ^nd more nutritive than the other ; and this latter is uied in the lafl week of incubation. r\ he yolk of an egg is (till a flronger or more nutritive fluid, which is drawn up into the bowels of the chick juft at its exclufion from the fhell, and ferves it for nourilh- rnent for a day or two, till it is able to digeft and has learnt to choofe the harder feeds or grains, which are to afford it fuftenance. Nothing analogous to this yolk is found in the fetus of lactiferous animals, as the milk is another nutritive fluid ready- prepared for the young progeny. The yolk therefore is not neceffary to the fpawn of fifh, the eggs of infedls, or for the feeds of vege- tables ; GENERATION. SECT. XXXTX. a. tables ; as their embryons have probably their food prefented to them as foon as they are ex- cluded from their fhells, or have extended their roots. Whence it happens that fome infe&s pro- duce a living progeny in the fpring and fummer, and eggs in the autumn ; and fome vegetables have living roots or buds produced in the place of feeds, as the polygonum viviparum, and magical onions. See Botanic Garden, p. ii, art. anthoxanthum. There feems however to be a refervoir of nutri- ment prepared for fome feeds beiides their catyle- dons or feed leaves, which may be fuppofed in fome meafure analogous to the yolk of the egg. Such are the faccharine juices of apples, grapes and other fruits, which fupply nutrition to the feeds after they fall on the ground. And fuch is the milky juice in the centre of the cocoa-nut, and part of the kernel of it; the fame I fuppofe of all other monocotyledon feeds, as of the palms, grafles, and lilies. II. i. The procefs of generation is full involved in impenetrable obfcurity, conje&ures may never- thelefs be formed concerning fome of its circum- ftances. Firfl, the eggs of fifl\ and frogs are im- pregnated, after they leave the body of the female, becaufe they are depofited in a fluid, and are not therefore covered with a hard {hell. ; It is however remarkable, that neither frogs nor fifh will part with their fpawn without the prefence of the male; on which account female carp and gold-fifh in fmall ponds, where there are no males, frequently die from the diftention of their growing fpawn. 2. The eggs of fowls, which are laid without being impregLared, aie feen to contain only the yolk and •white, which are evidently the food or fultenance for the future chick. 3. As the cicatricula of thefe eggs is given by the cock, and is evidently the ru- diment of the new animal, we may conclude, that the embryon is produced by the male, and the proper food and SF.CT. XXXIX. a. GENERATION. and nidus by the female. For if the female be fuppofed to form an equal part of the embryon, why fhould fhe form the whole of the apparatus for nutriment and for oxygenation ? the male in many animals is larger, ihonger, and digefls more food than the female, and therefore mould contribute as much or more towards the reprodu&ion of the fpe- cies ; but if he contributes only half the embvyon and none of the apparatues for fuiienance and oxygena- tion, the diviiion is ui equal ; the itrength ot trie male, and his confumption of food are too great for the effect, compared with that of the female, which is contrary to the ufual courle of nature. In objection to this theory of generation it may be faid, if the animalcula in femine, as feen by the microfcope, be all of them rudiments of homunculi, when but one of them can find a nidus, what a wafte nature has made of her productions ? I do not aflert that thefe moving particles, vilible by the mir crofcope, are homunciones ; perhaps they may be the creatures of ftagnation or putridity, or perhaps no creatures at all ; but if they are fuppofed to be rudiments of hoinunculi, or embryons, fuch a pro- fufion of them correfponds with the general effort of natufe to provide for the continuance of her fpecies of animals. Every individual tree produces innumerable feeds, and every individual fifh innume- rable fpawn, in fuch inconceivable abundance as would in a fhort fpace of time ciov.d the earth and ocean with inhabitants, and thefe are much more perfect animals than the animalcula in femine can be fuppofed to be, and perifh in uncounted milli- ons. This argument only fhevvs, that the producti- ons of nature are governed by general laws, and that by a wife fuperfluity of provifion fhe has en- fured their continuance. 2. That the embryon is fecreted or produced by the male, and not by the conjunction of fluids from t>oth male and female, appears from the analogy of vegetable GENERATION. SECT. XXX IX. a. vegetable feeds. In the large flowers, as the tulip, there is no fimilarity of apparatus between the an- thers and the ftigma : the feed is produced accord- ing to the obfervations of Spallanzani long before the flowers open, and in confequence long before it can be impregnated, like the egg in the pullet. And after the prolific duft is {hed on the ftigma, the feed becomes coagula'ed in one point firft, like the catri- cula of the impregnated egg> See Botanic Garden, Part I. additional note 38. Now in thefe fimple produces of nature, if the female contributed to produce the new embryon equally with the male, there would probably have been fome vilible fimi- larity of parts for this purpofe, befides thofe necef- fary for the nidus and fuftenance of the new pro- geny. Befides in many flowers the males are more numerous than the females, or than the feparate ute- rine cells in their germs, which would (hew, that the office of the male was at lead as important as that of the female ; whereas if the female, befides producing the egg or feed, was to produce an equal part of the embryon, the office of reproduction, would be unequally divided between them. Add to this, that in the moft fimple kind of ve- getable reproduction, I mean the buds of trees, which are their viviparous offspring, the leaf is evi- dently the parent of the bud, which rifes in its bofom, according to the obfervation of Linnaeus. This leaf confifts of abforbent veffels, and pulmo- nary ones, to obtain its nutriment, and to impreg- nate it with oxygene. This fimple piece of living organization is allo furnifhed with a power of re- production ; and as the new offspring is thus fup- ported adhering to its father, it needs no mother to fupply it with a nidus, and nutriment, and axy- genation; and hence no female leaf has exiftence. I conceive that the veffels between the bud and the leaf communicate or inofculate ; and that the bud is thus ferved with vegetable blood, that is, with S^cr. XXXIX. 2. GENERATION. 551 with both nutriment and oxygenation, till the death of the parent-leaf in autumn. And in this refpeft it differs from the fetus of viviparous animals. Se- condly, that then the bark-verTels belonging to the dead-leaf, and in which I fuppofe a kind of manna to have been depofited, become now the placenta! veflcls, if they may be fo called, of the new bud. Irom the vernal fap thus produced of one fugar- maple-ffee in New York and in Pennfylvania, five or fix pounds of good fugar may be made annually without defhoying the tree. Account of maple-fugar by B. Ruirr. London, Phillips. (See Botanic Garden, Part I. additional note on vegetable placentation.) Thefe veflels, when the warmth of the vernal fun hatches the young bud, ferve it with a faccharine nutriment, till it acquires leaves of its own, and {hoots a new fyftem of abforbents down the bark and root of the tree, juft as the farinaceous or oily matter in feeds, and the faccharine matter in fruits, ferve their embryons with nutriment, till they ac- quire leaves and roots. This analogy is as foiceable in fo obfcure a fubject, as it is curious, and may in large buds, as of the horfe-chefnut, be almoft feen by the naked eye ; if with a pen-knife the remain- ing rudiment of the lad year's leaf, and of the new bud in its bofom, be cut away flice by flice. The feven ribs of the laft year's leaif will be feen to have arifen from the pith in feven diflindl points making a curve ; and the new bud to have been produced in their centre, and to have pierced the alburnum and cortex, and grown without the afiiit* ance of a mother. A fimilar procefs may be feen oa differing a tulip root in winter ; the leaves, which inclofed the la(t year's flower-ftalk, were not necef- fary for the flower ; but each of thefe was the father of a new bud, which may be now found at its bafe ; and which, as it adheres to the parent,requiredno mother. This paternal offspring of vegetables, I mean their buds and bulbs, is attended with a very curious cir- cumftance ; GENERATION. SECT. XXXIX. *. ctimftance ; and that is, that they exaftly referable their parents, as is obfeivable in grafting fruit-trees, and in propagating flower-roots ; whereas the femi- nal offspring of plants, being fupplied with nutri- ment by the mother, is liable to perpetual variation. Thus alfo in the vegetable clafs dioicia, where the male flowers are produced on one tree, and the fe- male ones on another, the buds of the male trees uniformly produce either male flowers, or other buds fimilar to themfelve^ ; and the buds of the fe- male trees produce either female flowers, or other buds fimilar to themfelves ; whereas the feeds of thefe trees produce either male or female plants. From this analogy of the production of vegetable buds without a mother, I contend that the mother the great changes, which we fee naturally produced in ani- mals SECT. XXXIX, 4- GENERATION. 567 mals after their nativity, as in the preclusion of the butterfly with painted wings from the crawling caterpillar ; or of the refpiring frog from the fubna- tant tadpole ; from the feminine body to the bearded man, and from the infant girl to the la&efcent wo- man ; both which changes may be prevented by certain mutilations of the glands neceffary to repro- duction. Secondly, when we think over the great changes introduced into various animals by artificial or ac- cidental cultivation, as in horfes, which we have exercifed for the different purpofes of ftrength or fwiftnefs, in carrying burthens or in running races ; or in dogs, which have been cultivated for ftrength and courage, as the bull-dog ; or for acutenefs of his fenfe or fmell, as the hound and fpaniel ; or for the fwiftnefs of his foot, as the grey-hound ; or for his fwimming in the water, or for drawing fnow- iledges, as the rough-haired dogs of the north ; or laftly, as a play-dog for children, as the lap-dog ; with the changes of the forms of the cattle, which have been domefticated from the greateft antiquity, as camels, and fheep ; which have undergone fo total a transformation, that we are now ignorant from what fpecies of \vild animals they had their ori- gin. Add to thefe the great changes of lhape and colour, which we daily fee produced in fmaller ani- mals from our domeftication of them, as rabbits, or pigeons ; or from the difference of climates and even of feafons ; thus the fheep of warm climates are covered with hair inftead of wool ; and the hares and partridges of the latitudes, which are long buried in fnow, become white during the winter months ; add to thefe the various changes produced in the forms of mankind, by their early modes of exertion ; or by the difeafes occalioned by their habits of life ; both of which became hereditary, and that through many generations. Thofe who labour 568 GENERATION. SECT. XXXIX. 4. labour at the anvil, the oar, or the loom, as well as thofe who carry fedan-chairs, or who have been educated to dance upon the rope, are diftinguifh- able by the fhape of their limbs ; and the difeafes occafioned by intoxication deform the countenance with leprous eruptions, or the body with tumid vifcera, or the joints with knots and diftortions. Thirdly, when we enumerate the great changes produced in the fpecies of animals before their na- tivity ; thefe are fuch as referable the form or co- lour of their parents, which have been altered by the cultivation or accidents above related, and are thus continued to their pofterity. Or they are changes produced by the mixture of fpecies, as in mules ; or changes produced probably by the exu- berance of nourishment fupplied to the fetus, as in monftrous births with additional limbs; many of thefe enormities of fhape are propagated, and con- tinued as a variety at leaft, if not as a new fpecies of animal. I have feen a breed of cats with an ad- ditional claw on every foot ; of poultry alfo with an additional claw, and with wings to their feet ; and of others without rumps* Mr. Buffon menti- ons a breed of dogs without tails, which are com- mon at Rome and at Naples, which he fuppofes to have been produced by a cuftorn long eftablifhed of cutting their tails clofe off. There are many kinds of pigeons, admired for their peculiarities, which are monflers thus produced and propagated, And to thefe muft be added, the changes produced by the imagination of the male parent, as will be treated of more at large in No. VI. of this Section* When we confider all thefe changes of animal form, and innumerable others, which may be col- lected from the books of natural hiftory ; we can- not but be convinced, that the fetus or embryon is formed by apportion of new parts, and not by the diftention SECT. XXXIX. 4. GENERATION. 5^ diftention of a primordial neft of germs, included one within another, like the cups of a conjurer. Fourthly, when we revolve in our minds the great fimilarity of ftrudure, which obtains in all the warm-blooded animals, as well quadrupeds, birds, and amphibious animals, as in mankind ; from the moufe and bat to the elephant and whale ; one is led to conclude, that they have alike been produced from a fimilar living filament. In fome this filament in its advance to maturity has acquired hands and fingers, with a fine fenfe of touch, as in mankind. In others it has acquired claws or talons, as in tigers and eagles. In others, toes with an intervening web or membrane, as in feals and geefe* In others it has acquired cloven hoofs, as in cows and fwine ; and whole hoofs in others, as in the horfe. While in the bird kind, this original living filament has put forth wings inftead of arms or legs, and feathers inftead of hair. In fome it has pro- truded horns on the forehead inftead of teeth in the forepart of the upper jaw ; in others tufhes inftead of horns ; and in others beaks inftead of either. And all this exactly as is daily fcen in the tranf- mutations of the tadpole, which acquires legs and lungs, when he wants them ; and lofes his tail, when it is no longer of fervice to him. Fifthly, from their firft rudiment, or primordium, to the termination of their lives, all animals under- go perpetual transformations ; which are in part produced by their own exertions in confequence of their deiires and averfions, of their pleafures and their pains, or of irritations, or of affociations; and many of thefe acquired forms or propenfuies are transmitted to their pofterity. See Sect, XXXI. j. As air and water are fupplied to animals in fuffi- cient profufion, the three great objecls of defire, which have changed the forms of many animals by tfyeir exertions to gratify them, are thofe of luft, hunger^ GENERATION. SECT. XXXIZ- 4. hunger, and fecurity. A great want of one part of the animal world has confifted in the defire of the exclufive pofleflion of the females ; and thefe have acquired weapons to combat each other for this purpofe, as the very thick, fhield-like, horny fkin on the fhoulder of the boar is a defence only againft animals of his own fpecies, who ftrike ob- liquely upwards, nor are his tufhes for other pur- pofes, except to defend himfelf, as he is not natu- rally a carnivorous animal. So the horns of the Hag are fharp to offend his adverfary,but are branch- ed for the purpofe of parrying or receiving the thrufts of horns fimilar to his own, and have there- fore been formed for the purpofe of combating other flags for the exclufive pofleffion of the females; who are obferved, like the ladies in the times of chi- valry, to attend the car of the victor. The birds, which do not carry food to their young, and do not therefore marry, are armed with fpurs for the purpofe of fighting for4:he exclufive pofleflion of the females, as cocks and quails. It is certain that thefe weapons are not provided for their defence againft other adverfaries, becaufe the females of thefe fpecies are without this armour. The final caufe of this conteft amongft the males feems to be, that the ftrongeft and moft active ani- mal fhould propagate the fpecies, which fhould thence become improved. Another great want confifts in the means of pro- curing food, which has diverfified the forms of all fpecies of animals. Thus the nofe of the fwine has become hard, for the purpofe of turning up the foil in fcarch of infects and of roots. The trunk of the elephant is an elongation of the nofe for the purpofe of pulling down the branches of trees for his food, and for taking up wateV without bend- ing his knees. Beafts of prey have acquired ftrong jaws or talons. Cattle have acquired a rough tongue and SECT. XXXIX. 4. GENERATION. 571 and a rough palate to pull off the blades of grafs, as cows and fheep. Some birds have acquired hard- er beaks to crack nuts, as the parrot. Others have acquired beaks adapted to break the harder feeds, as fparrows. Others for the fofter feeds of flowers, or the buds of trees, as the finches. Other birds have acquired long beaks to penetrate the moifter foils in fearch of infects or roots, as woodcocks • and others broad ones to filtrate the water of lakes, and to retain aquatic infects. All which feem to have been gradually produced during many gene- rations by the perpetual endeavour of the creatures to fupply the want of food, and to have been de- livered to their pofterity with conftant improvement of them for the purpofes required. The third great want amongft animals is that of lecurity, which feems much to have diverfified the forms of their bodies and the colour of them ; thefe confift in the means of efcaping other animals more powerful than themfelves. Hence fome animals have acquired wings inftead of legs, as the fmaller birds, for the^purpofe of efcape. Others great length of fin, or of membrane, as the flying fifh, and the bat. Others great fwiftnefs of foot, as the hare. Others have acquired hard, or armed fjiells, as the tortoife and echinus marinus. Mr. Ofbeck, a pupil of Linnaeus, mentions the American frogfifhj Lophius Hiftrio, which inhabits the large floating iflands of fea weed about the Cape of Good Hope, and has fulcra refemblin-g leaves, that the fifhes of prey may miftake it for the fea- weed, which it inhabits. Voyage to China, p. 1 13. The contrivances for the purpofes of fecurity ex- tend even to vegetables, as is feen in the wonderful and various means of their concealing or defending their honey from infects, and their feeds from birds. On the other hand fwiftnefs of wing has been ac- quired by hawks and fwallows to purfue their prey; VOL. I. P p and jand volvox ; and the fimplicity of which is an argument in favour of the iimilarity of its caufe. Linnaeus fuppofes, in the Introduction to his Na- tural Orders, that very few vegetables were at tirft created, and that their numbers were iucreafed by their intermarriages, and adds, fuadent hsec Crea* toris leges a fimplicibus ad compofita. Many other changes feem to have arifen in them by their per- petual conteft for light and air above ground, and for food or moifture beneath the foil. As noted in Botanic Garden, Part II. Note on Cufcuta. Other changes of vegetables from climate, or other caufes, are remarked in the Note on Curcuma in the fame work. From thefe one might be led to imagine, that each plant at fiift confilted of a fingle bulb, or flower to each root, as the gentianella and daify j and that in the conteft for air and light, new buds grew on the old decaying flower item, fhooting down their elongated roots to the ground, and that in procefs of ages tall trees were thus formed, and an individual bulb became a fwarm of vegetables. Other plants, which in this conteft for light and air were too flender to rife by their own ftrength, learn- ed by degrees to adhere to their neighbours, either by putting forth roots like the ivy, or by tendrils like the vine, or by fpiral contortions like the honey- fuckle; SECT. XXXIX. 4 GENERATION. 575 fuckle ; or by growing upon them like the mifleto, and taking nourifhment from their barks ; or by only lodging or adhering on them, and deriving nourifhment from the air, as tillandfia. Shall we then fay the vegetable living filament was originally different from that of each tribe of animals above defcribed ? And that the productive living filament of each of thofe tribes was diffeient originally from the other? Or, as the earth and ocean were probably peopled with vegetable pro- ductions long before me exiftence of animals ; and many families of thefe animals long before other families of them, fhall we conje&ure that one and the fame kind of living filaments is and has been the caufe of all organic life ? This idea of the gradual formation and improve- ment of the animal world accords with the obfer- vaiions of fome modern philofophers, who have fup- pofed ihat the continent of America has been raifed out of the ocean at a later period of time than the other three quarters of the globe, which they de- duce from the greater comparative heights of its mountains, and the confequent greater coldnefs of its refpeftive climates, and from the lefs fize and ftrength of its animals, as the tigers and alligators compared with thofe of Afia or Africa. And laftly, from the lefs progrefs in the improvements of the mind of its inhabitants in refpeft to voluntary excr- cions. This idea of the gradual formation and improve- ment of the animal world feems not to have been unknown to the ancient philofophers. Plato having probably obferved the reciprocal generation of in- ferior animals, as fnails and worms, was of opinion, that mankind with all other animals were originally hermaphrodites during the infancy of the world> and were in procefs of time feparated into male and female. The brealls and teats of all male quadru- 576 G E ¥ EjSL AT JO N. SECT. XXXIX. 4. peds, to which no ufe can now.be affigned, adds perhaps forac fhadpw of probability to this opinion. Linnaeus excepts the horfe from the male quadru- peds, who have teats ; which might have Qiewn the earlier origin of his exiftence ; but Mr. J. Hunter aliens, that he has discovered the veftiges of them jon his fheatb, and has at the fame time enriched natural hiflory with a very curious fa& concerning the male pigeon ; at the time of hatching the eggs both the male and female pigeon undergo 3 great change in their crops ; which thicken and become corrugated, and fecrete a kind of milky fluid, which coagulates, and with which alone they for a few days feed t)ieir young, and afterwards feed them with this coagulated fluid mixed with other foodc How this refembles the breafts of female quadru- peds after the production of their young ! and how extraordinary, that the male fhould at this time give piilk as 'well as the female I See Botanic Garden, Part II. Note on Curcuma. The late Mr. David Hume, in his pofthurnous works, places the powers of generation much above thofe of our boafted reafoh ; and adds, that reafon can only make a machine, as a clock or a fhip, but the power of generation makes the maker of the •machine ; and probably from having obfervcd, that the greateft part of the earth has been formed out of organic recrements ; as the immenfe beds of lime- ftone, chalk, marble, from the fhells of fifh ; and the extenfive provinces of clay, fandfione, ironftone, coals, from decompofed vegetables ; all which have -been firft produced by generation, or by the fecre- tions of organic life ; he concludes that the world itfelf might have been generated, rather than cre- ated; that is, it might have been gradually pro- duced from very fmall beginnings, increaiing by the aelivity of its' inherent principles, rather than by a fuddcn evolution of the whole by the Ai- afrtf mighty SECT. XXXIX. 5. G E N E R A T 1 O N'. j-;;; mighty fire. — What a magniiiccnt idea of ihc infinite power of THE GREAT AR CHITECT ! TntCA USE OF C A u s LS ! PA R i: N T OF PARENTS! ENS E x T iu M 1 For if we may compare infinities, it would feern to require .a greater infinity of power to caufe the caufes of effects, than to caufe the efieds them- felves. This idea is analogous to the improving ex- cellence ofoiervable in every part of the creation ; fuch as in the progrcffive increafe of the folid or habitable parts of the earth from waier ; and in the progreflive increafe of the wifdom and happinefs of its inhabitants ; and is confonant to the idea of our prefent fituation beingaiiate of probation, which by ojr exertions we may improve, and arc confe- quently refponfible for our adtions. V.i. The efficient caufe of the various colours of the eggs of birds, and of the hair and feathers of animals, is a fubjcct fo curious, that I fhall beg to introduce it in this place. The colours of many animals feem. adapted to their purpofes of concealing themfelves cither to avoid danger, or to fpring upon their prey. Thus the fnake and wild cat, and leopard, are fo coloured as to referable dark leaves and their lighter interfaces ; birds refemble the colour of the brown ground, or the green hedges, which they frequent ; and moths and butterflies are coloured like the flowers which they rob of their honey. Many inflances are mentioned of this kind in Bo- tanic Garden, p. 2. Note on Rubia. Thcfe colours have, however, in fome inflances another ufe, as the black diverging area from the eyes of the fwan ; which, as his eyes are placed lefs prominent than thofe of other birds, for the convenience of putting down his head under water, prevents the rays of light from being reflected into his eye, and thus dazzling his fight, both in air and beneath the water ; which mufl have happened, if tha 578 GENERATION. SECT. XXXIX. 5, that furface had been white like the reft of his feathers. There is a ftill more wonderful thing concerning thefe colours adapted to the piirpofe of conceal- ment ; which is, that the eggs of birds are fo co- l6ured as to refemble the colour of the adjacent objects and their interftices. The eggs of hedge- birds are greenifh with dark fpots ; thofe of crows and magpies, which are feen from beneath through wicker nefts> are white with dark fpots; and thofe of larks and partridges are ruflet or brown, like tiheir nefts or fituations. A thing ftill more aftonifhing is, that many ani- mals in countries covered with fnow become white in winter, and are faid to change their colour again in the warmer months, as bears, hares, and par- tridges. Our domefticated animals lofe their natu- ral colours, and break into great variety, as horfes, dogs, pigeons. The final caufe of thefe colours is eafily underftood, as they ferve fom'e purpofes of the animal, but the efficient caufe would feem al- triQft beyond conjecture. Firft, the choroid coat of the eye, on which the femitranfparent retina is expanded, is of different colour in different animals ; in thofe which feed on grafs it is green ; from hence there wbuld appear fome connexion between the colour of the choroid coat and of that conftantly painted on the retina by the green grafs. Now, wheri the ground becomes covered with fnow,' it would feem, that that action of the retina, which is called whitenefs, being con- ftantly excited in the' eye, maybe gradually imi- tated by the extremities of the nerves of touch, or rete m'ucofum of the fkin.; And if it be fuppofed, that the a&ion of the retina in 'producing the per- fception of any colour confifts in fo difpofing its own fibres or furface, as to refl^cl thofe coloured rays only, and tranfmit the others like foap-bub- bles; SECT. XXXIX. $. GENERATION, 579 bles ; then that part of the retina, which gives us the perception of fnow, muft at that time be white ; and that which gives us the perception of grafs, mull be green. Then if by the laws of imitation, as explained in Section XIL 33. and XXXIX. 6. the extremities of the nerves of touch in the rete muKZofum be in- duced intofimilar action, the fkin or feathers, or hair, may in like manner fo difpofc their extreme fibres, as to reflect white ; for it is evident, that all thefe parts were originally obedient to irritative mo- tions during their growth, and probably continue to be fo ; that thofe irritative motions are not liable in a healthy ftate to be fucceedcd by fenfation ; which however is no uncommon thing in their dif- eafed ftate, or in their infant ftate, as in plica po- lonica, and in very young pen-feathers, which are ftill full of blood. It was fhewn in Section XV. on the Production of Ideas, that the moving organ of fenfe in fome cir- cumflances refembled the object which produced that motion. Hence it may be conceived, that the rete mucofum, which is the extremity of the nerves of touch, may by imitating the motions of there- tina become coloured. And thus, like the fable of the camelion, all animals may poflefs a tendency to be coloured fomewhat like the colours they moil frequently infpect ; and finally, that colours may be thus given to the egg-fhell by the imagination of the female parent ; which fhell is previoufly a mu- £ous membrane, indued with irritability, without which it could not circulate its fluids, and incre^fe in its bulk. Nor is this more wonderful than that a fingle idea of imagination fliould in an inftant co- lour the whole furface of the body of a bright fear- let, as in the blufh of fhame, though by a very* different procefs. In this intricate fubject nothing loofe analogical conjectures can be had, which roay S^o G E N $ R A T I O N. SECT. XXXIX. 5 may however lead to future difcoveries; but certain it is that both the change of the colour of animals to- white in the winters of fnowy countries, and the fpots on birds eggs, muft have fome efficient caufe ; fince the uniformity of their production ftiews it cannot arife from a fortuitous concurrence of cir- cumftances ; and how is this efficient caufe to be detected, or explained, but from its analogy to other animal fads ? 2. The nutriment fupplied by the female parent in viviparous animals to their young progeny may be divided into three kinds, correfponding with the age of the new creature, i. The nutriment con- tained in the ovum as previoufly prepared for the embryon in the ovary. 2. The liquor amnii pre- pared for the fetus in the uterus, and in which it fwims ; and laftly, the milk prepared in the peclo- ral glands for the new born child. There is reafon to conclude, thaft variety of changes may be pro- duced in the new animal from all thefe iburces of nutriment, but particularly from the firft of them. The organs of digeftion and of fanguification in adults, and afterwards thofe of fecretion, prepare or feparate the particles proper for nourifhment from other combinations of matter, or recombine them into new kinds of matter, proper to excite in- to action the filaments, which abforb or attract them by animal appetency. In this procefs we muft at- tend not only to the action of the living filament, which receives a nutritive particle to its bofom, but alfo to the kind of particle, in refpect to form, or fize, or colour, or hardnefs, which is thus previ- oufly prepared for it by. digeftion, fanguificaiion, and fecretion. Now as the firft filament of entity cannot be furnifhcd with the preparative organs above mentioned, the nutritive particles, whiehare at firft to be received by it, are prepared by the 'mother; and dcpofned in the ovum ready for its reception SECT. XXXIX. 5. G E NT E R A T I O N. 581 reception. Thefe nutritive particles mufi be fup- pofed to differ in fome refpc&s, when thus prepared by different animals. They may differ in f:ze, co- lour, and form ; and yet may he fufficiently con- genial to the living filament, to which they arc ap- plied, as to excite its activity by their flimulus, and its animal appetency to receive them, and U) com- bine them with it fell' into organization. By this firft nutriment thus prepared for the cm- 5bryon is not meant the liquor amnii, which is af- terwards produced, nor the larger exterior parts of the white of the egg ; but the fluid prepared, I Juppofe, in the ovary of viviparous animals, and that which immediately furrounds the cicatricula of an impregnated egg, and is vifible to the eye in a boiled one. Now thefe ultimate particles of animal matter pre- pared by the glands of the mother may be fuppofed to refemble the fimilar uliimate particles, which were prepared for her own nourifhment ; tjiat is, to the ultimate particles of which her own organiza- tion confifts. And that hence when thefe become combined with a new embryon, which in its early flate is not furnifhed with ftomach, or glands, to alter them ; that ncwr embryon will bear fome rc- femblance to the mother. This feems to be the origin of the compound forms of mules, which evidently panake of both parents, but principally of the male parent. In this production of chimeras the anticms fecin lo have indulged their fancies, whence the fphinxcs, griffins, dragons, centaurs, and minotaurs, which are vanifhed from modern credulity. It would fcem, that in thefe unnatural conjucc- tions, when the nutriment depofitcd by the female was fo ill adapted to Simulate the living filament derived from the male into a6lion, and to be re- ceived, or embraced by it, and combined wiih it into $8* GENERATION. SECT. XXXIX. 5, into organization, as not to produce the organs ne- ceflary to life, as the brain, or heart, or ftomach, that no mule was produced. Where all ihe parts ncceflary to life in thefe compound animals were formed fufficiemly perfect, except the parts of ge- neration, thofe animals were produced which are now called mules. The formation of the organs of fexual genera^ lion, in comradiftin6tion to that by lateral buds, in vegetables, and in forne animals, as the polypus, the tasnia, and the volvox, feems the chef d'oeuvre, the matter- piece of nature ; as appears from many flying infers, as in moths and butterflies, who feem to undergo a general change of their forms folely for the purpofe of fexual reproduction, and in all other animals this organ is not complete till the maturity of the creature. Whence it happens that, in the copulation of animals of different fpecies, the parts neceflary to life are frequently completely- formed ; but thofe for the purpofe of generation are defective, as requiring a nicer organization; or more exa& coincidence of the particles of nutriment to the irritabilities or appetencies of the original living filament. Whereas thofe mules, where all the parts could be perfectly formed, may have been produced in earlier periods of time, and may have added to the numbers of our various fpecies of animals, $s before obferved. As this production of mules is a conftant effect from the conjun&ion of two different fpecies of ani- mals, thofe between the horfe and the female afs always r^fembling the horfe more than the afs; and thofe, on the contrary, between the male afs and the mare, always refembling the afs more than the mare ; it cannot be afcribed to the imagination, of the male animal which cannot be fuppoicd to operate fo uni- formly ; but to the form of the firft nutritive par- ticles, and to their peculiar flimulus exciting the living £*CT. XXXIX. 5. GENERATION. 5*3 living filament to fele<5l and combine them with it- felf. There is a fimilar qntfonmii of effect in rc- fped to the colour of the progeny produced be- tween a white man, and a black woman, which, if I am well informed, is always of the mulatto kind, or a mixture of the two ; which may perhaps be imputed to the peculiar form of the particles of nutriment fupplied to the embryon by the mother at the early period of its exiftence, and their pecu- liar ilimulus; as this effect, like that of the mule progeny above treated of, is uniform and confident, and cannot therefore be afcribed to the imagination of either of the parents. Dr. Thunberg obferves, in his Journey to the Cape of Good Hope, that there are fome families, which have defcended from blacks in the female kne for three generations. The firft generation pro- ceeding from an European, who married a tawny Have, remains tawny, but approaches to a white com- plexipn y but ihe children of the third generation, Anixed with Europeans, become quite white, and are often remarkably beautiful. V. i. p. 112. When the embryon has produced a placenta, and furnifhed itfelf wiih veiFels for [election of nutri- tious particles, and for oxygcnation of them, no great change in its form or colour is likely to be produced by the particles of fuftenancc it now takes from the fluid, in which it is immerfed ; becaufe it has now acquired organs to alter or new combine them. Hence it continues to grow, whether this fluid, in which it fwims, be formed by the uterus or by any other cavity of the body, as in extra- uterine. geftation ; and which would feem to be pro- duced by the ilimulus of the fetus on the fides of the cavity, where it is found, as mentioned before. And thirdly, there is ftiJl lefs reafon to expect any unnatural change to happen to the child after its birth from the difference of the milk it now takes ; beeaufe GENERATION. SECT. XXXIX. 5. becaufe it has acquired a ftomach, and lungs, and glands, of fufficient power to decompofe and re- combine the milk ; and thus to prepare from it the various kinds of nutritious particles, which the ap- petencies of the various fibrils or nerves may re- quire. From all this reafoning I would conclude, that though the imagination of the female may be fup« pofed to affecl: the embryon by producing a differ- ence in its early nutriment ; yet that no fuch pow- er can affcft it after it has obtained a placenta, and other organs ; which may fele6l or change the food, which is prefemcd to it either in the liquor amnii, or in the milk. Now as the eggs in pullets, like the feed> in vegetables, are produced gradually, long before they are' impregnated, it does not appear how any fudden effect of imagination of the mother, at the time of impregnation, can produce any confiv derable change in the nutriment already thus laid up for the expected or defired embryon. And that hence any changes of the embryon, except thofe uniform ones in the production of mules and mu- lattoes, more probably depend on the imagination of the male parent. At the fame time it feems ma- nifeft, that thofe monftrous births, which confift in fome deficiencies only, or fome redundancies of parts, originate from the deficiency or redundance of the firit nutriment prepared in the ovary, or in the part of the egg immediately furrounding the cicatricula, as defcribed above; and which continues fome time to excite the firft living filament into action, after the fimple animal is completed ; or ceafes to excite it, before the complete form is ac- complifhed. The former of thefe circumftances is evinced by the eggs with double yolks, which fre- quently happen to our domefticated poultry, and which, I believe, are fo formed before impregna- tion, but which would be well worth attending to, both . XXXIX. 6. GENERATION. 585 both before and after impregnation ; as it is proba- ble, fomething valuable on this fubject might be learnt from them. The latter circumftancc, or that of deficiency of original nutriment, may be deduced from reverfe analogy. There are, however, other kinds of monftrcus births, which neither depend on deficiency of parts, or fupernumerary ones ; nor are owing to the con- junction of animals of different fpecies ; but which appear to be new conformations, or new difpofiii- ons of parts in refpeft to each other, and which, like the variation of colours and forms of our domefti- catecl animals, and probably the fexual parts of all animals, may depend on the imagination of the male parent, which we now come to confider. VI. i. The nice actions of the extremities of our- Carious glands are exhibited in their various pro* duclions, which are believed to be made by the gland, and not previoufly to exift as fuch in the blood. Thus the glands, which conftitute the liver, make bile ; thole of the ftomach make gaftric acid ; thofc beneath the jaw, faliva; thofe of the ears, ear-wax, and the like. Every kind of gland muft poffefs a peculiar irritability, and probably a i'enfibiliiy, at the early fiate of its exigence ; and in eft be furnifhed with a nerve of fenfe, or of mo- tion, to perceive, and to felecl, and to combine the particles, which compofe the fluid it fecretes. And this nerve of fenfc which perceives the differ- ent articles which compofe the blood, muft at leaft be conceived to be as fine and fubtle an organ, as the opiic or auditory nerve, which perceive light or fo'irid. See Sea. XIV. 9. But in nothing is this nice action of the extremi- of the blood-veffels fo wonderful, as in the pro- duction of contagious matter. A fmall drop of variolous contagion diffufed in the blood, or per- haps only by being inferted beneath the cuticle, after 586 O E N E R A T I O N. SECT. XXXIX. 6. after a time, (as about a quarter of a lunation,) ex- cites the extreme veflels of the fkin into certain motions, which produce a fimilar contagious mate- rial, rilling with it a thoufand puftules. So that by irritation, or by ienfation in confequence of irri- tation, or by affociation of motions, a material is formed by the extremities of certain cutaneous vef- fels, exadly fimilar to the ft imulating material, which caufed the irritation, or eonfequent fenfation, or affociation. Many glands of the body have their motions, and in confequence their fecreted fluids, affe&ed by pleafurable or painful ideas, fince they are in many instances influenced by fenfitive affociations, as well as by the irritations of the particles of the palling blood. Thus the idea of meat, excited in the minds of hungry dogs, by their fenfe of vifion, or of fmell, increafes the difcharge of faliva, both in quan- tity and vifcidity ; as is feen in its hanging down in threads from their mouths, as they ftand round a dinner-table. The fenfations of pleafure, or of pain, of peculiar kinds, excite in the fame manner a great difcharge of fears ; which appear alfo to be more faline at the time of their fecretion, from their in- flaming the eyes and eye-lids. The palenefs from fear, and the blufh of fhame, and of joy, are other inftances of the effects of painful, or pleafurable fenfations, on the extremities of the arterial fyftem. It is probable, that the pleafurable fenfation ex- cited in the ftomach by food, as well as its irrita- tion, contributes to excite into a6lion the gaftric glands, and to produce a greater fecretion of their fluids. The fame probably occurs in the fecretion of bile ; that is, that the pleafurable fenfation ex- cited in the ftomach, afTecls this fecretion by fenfi- tive affociation, as well as by irritative affociation. And laftly it would feem, that all the glands in the body have their fecreted fluids affected, in quan- tity Siicr.XXXlX. 6. GENERATION. 587 thy and quality, by the pleafurable or painful fen- fations, which produce or accompany thofe fecre- tions. And that the pleafurable fenfations arifing from thefe fecretions may conftitute the unnamed pleafure of exiftence, which is contrary to what is meant by taedium vitse, or ennui ; and by which we fometimes feel ourfelves happy, without being able to afcribe it to any mental caufe, as after an agree- able meal, or in the beginningoof intoxication. Now it would appear, that no fecretion or excre- tion of fluid is attended with Ib much agreeable fenfation, as that of the femen ; and it would thence follow, that the glands, which perform this fecre- tion, are more likely to be much affected by their catenations with pleafurable fenfations. This cir- cumftance is certain, that much more of this fluid is produced in a given time, when the objedl of its excluiion is agreeable to the mind. 2. A forcible argument, which fhews the necef- fity of pleafurable fenfation to copulation, is, that the a£t cannot be performed without it ; it is eafily interrupted by the pain of fear or bafhfulnefs ; and no efforts of volition or of irritation can eflec-l this procefs, except fuch as induce pleafurable ideas of fenfations. See Sea. XXXIII. I. i. A curious analogical circtimflance attending her- maphrodite infers, as fnails and worms, ftill fur- ther illuftrates this thueory; if the fnail or worm could have impregnated itfelf, there might have been a faving of a large male apparatus ; but as this is not fo ordered by nature, but each fnail and worm receives and gives impregnation, it appears, that a pleafurable excitation feems alfo to have been required. '1 his wonderful circumftance of many infecls be- ing hermaphrodites, and at the fame time not hav- ing power to impregnate themfelves, is attended to by Dr. Lifter, in his Exeicitationes Anatom. de VOL. I. Q^q Liinacibus, 588 GENERATION. SECT. XXXIX. 6. Limacibus, p. 145; who, amongft many other final caufes, which he adduces to account for it, adds, ut tarn triflibus et frigidis animalibus majori cum voluptate perficiatnr venus. 1 here is, however, another final caufe, to which this circumftance may be imputed : it was obferved above, that vegetable buds and bulbs, which are produced without a mother, are always exaft re- iemblances of thei* parent ; as appears in grafting fruit-trees, and in the flower-buds of the dioiceous plants, which aie always of the fame lex on the fame tree; hence thofe hermaphrodite infects, if they could have produced young without a mother, would not have been capable of that change or im- provement, which is feen in all other animals, and in thofe vegetables, which are procreated by the male embryon received and nourished by the female. And it is hence probable, if vegetables could only have been produced by buds and bulbs, and not by fexual generation, that there would not at this time have exifted one thoufandth part of their ptefent number of fpecies ; which have probably been originally mule-prpJudtions; nor could any kind of improvement or change have happened to them, except by the difference of foil or climate. 3. I conclude, that the imagination of the male at the time of copulation, or at the time of the fe* cretion of the femen, may fo affeci this fecretion by irritative or fenfitive affociation, as defcribed in No. q. i. of this Section, as to caufe the production of fimilarity of form and of features, with the diftinc- tion of lex ; as the motions of the chifiel of the turner imitate or correfpond with thofe of the ideas of the artift. It is not here to be underftood, that the firft living fibre, which is to form an animal, is produced with any fimilarity of form to the future animal ; but with propenfities, or appetences, which fnall produce by accretion of parts the fimilarity of form, . XXXIX. 6. GENERATION. 589 form, feature, or fex, correfponding to the imagin- ation of the father. Our ideas are movements of the nerves of fenfe, as of the optic nerve in recollecting vifible ideas, fuppofe of a triangular piece of ivory* The fine moving fibres of the retina ad in a manner to which I give the name of white \ and this action is con- fined to a defined part of it ; to which figure I give the name of triangle. And it is a preceding plea- furable ienfatton exifting in my mind, which occa- lions me to produce this particular motion of the- retina, when no triangle is preient. Now it is pro- bable, that the acting fibres of the ultimate termin- ations of the fecreting apertures of the veffels of tho teftes, are as fine as thoTe of the retina; and that they are liable to be thrown into that peculiar action, which marks the fex of the fecreted embryon, by fympa- thy with the pleafurable motions of the nerves of vifion or of touch ; that is, with certain ideas of imagination. From hence it would appear, that the world has been long miilaken in afcribing great pow- er to the imagination of the female, whereas from this account of it, the real power of imagination, in the act of generation, belongs folely to the male. See Sea. XII. 3. 3. It may be objected to this theory, that a man may be fuppofed to have in his mind, the idea of the form and features of the female, rather than his own, and therefore there ihould be a greater num- ber of female births. On the contrary, the general idea of our own form occurs to every one almoft perpetually, and is termed confcioufnefs of our ex- iftence, and thus may effect, that the number of males furpaffes that of females. See Sect. XV. 3. 4* and XVIII. 13. And what farther confirms this idea is, that the male children molt frequently re^ femble the father in form, or feature, as well as in fex ; and the female mod frequently refemble the mother, 590 GENERATION. SECT. XXXIX. 6. mother, in feature, and form, as well as iu fex. It may again be obje&ed, if a female child fome- rimes refenvbles the father, and a male child the mo- ther, the ideas of the father, at the time of procie- ation, mud fuddenly change from himfelf to the mother, at the very inflant, when the embryon is fecreted or formed. This difficulty ceafes when we coniider, that it is as eafy to form an idea of femi- nine featuies with male organs of le production, or of male features with female ones, as the contrary; as we conceive the idea of a fphinx or mermaid as eafily and as diftinctly as of a woman. Add to this, that at the time of procreation the idea of the male organs, and of the female features, are often both excited at the fame time, by contact, or by vifion. I afk, in my turn, is the fex of the embryon pro- duced by accident ? Certainly whatever is produced has a caufe; but when this caufe is too minute for our comprehenilon, the effect is faid in common lan- guage to happen by chance, as in throw ing a certain number on dice. Now what caufe can occafionally produce the male or female cha racier of the embry- on, but the peculiar actions of thole glands, which form the embryon ? And what can influence or go- vern the'fe actions of the gland, but its affociations or catenations with other ienfitive motions ? Nor is this more extraordinary, than that the catenations of irritative motions with the apparent vibrations of objedls at fea fhould produce ficknefs of the ftomach, or that a naufeous flory fhould occafion vomiting. 4. An argument, which evinces the effecl of ima- gination on the firft rudiment of the embryon, may be deduced from the production of fome peculiar monfteis. Such, for infbnce, as thofe which have i wo heads joined to one body, and thofe which have two bodies joined to one head ; of w:hich frequent t.xarnples occur amongft our clomefticaUd quadiu- peds, JLCT. XXXIX. 6. GENERATION. 591 peds, and poultry. It is abfurd to fuppofe, that luch forms could exift in primordial germs, as ex- plained in No. IV. 4. of this Section. Nor is it poflible, thut fuch deformities could be produced by the growth of two embryons, or living filaments 5 which fhould afterwards adhere together; as the head and tail part of different polypi are faid to do (Blumenbach on Generation, Cadel, London) ; fince in that cafe one embryon, or living filament, muft have begun to form one part fir It, and the other another part fir ft. But fuch monlhous conforma- tions become lefs difficult to comprehend, when they are conlldered as an effect of the imagination, as before explained, on the living filament at the time of its fecretion ; and that fuch duplicature of limbs were produced by accretion of new parts, in confequence of propenlities, or animal appetencies thus acquired from the female parent. For inilance, I can conceive, if a turkey-cock fhould behold a rabbit, or a frog, at the time of pro- creation,-'that it might happen, that a forcible or even a pieafurable idea of the form of a quadruped might fo occupy his imagination, as to caufe a ten- dency in the nafcent filament to refemble fuch a form, by the apportion of a duplicature of limbs. Experiments on the production of mules and mon- fters would be worthy the attention of a Spallan- zani, and might throw much light upon this fubjecl, which at pieient mud be explained by conjectural analogies. The wonderful effect of imagination, both in the male and female paicnt, is fhewn in the production of a kind of -milk in the crops both of the male and female pigeons after the birth of their young, as obferved by Mr. Hunter, and mentioned before. To this mould be added, that there are fome inftances ot men having had milk fecreted in their breads, and who have given fuck to children, as recorded $9* GENERATION. SECT. XXXIX. 6. by Mr. BufFon. This efFccl of imagination, of both the male and female parent, feems to have been at- tended loin very early times ; Jacob is faid not only to have placed rods of trees, in part ftripped of their bark, fo as to appear fpotted, but ajfo to have placed fpotted lambs before the flocks, at the time of their copulation. Genefis, chap. xxx. vei fe 40. 5. In refpedl to the imagination of the mother., it is difficult to comprehend, how this can produce any al eration in the fetus, except by affie6Ung the nutri- ment laid up for its nrft reception, as defcribed in No. V. 2. of this fedlion, or by affe&ing the nourifhment or oxygenation \' ith which {he fuppliesit afterwards. Perpetual anxiety may probably affeft the fecretion of the liquor amnii into the uterus, as it enfeebles the whole fyftem; andfudden fear is a frequent caufe of mifcarriage ; for fear, contrary to joy, decreafes for a time the action of the extremities of the arterial fyftem ; hence Hidden palenefs fucceeds, and a fhrinking or contraction of the veffels of the ikin, and other membranes. By this circumitance, I imagine, the terminations of the placenul veflels are detached from their adhefions, or infertions, into the membrane of the uterus ; and the death of the child fucceeds, and confequent mifcarnage. Of this I recoiled! a remarkable inftance, which could be afcribed'to no other caufe, and which I fhall therefore relate in few words. A healthy young woman, about twenty years of age, had been about five months pregnant, and going down into her cellar to draw fome beer, was frighted by a fervaut boy ftarting up from behind the barrel, wheie he had concealed himfelf with defign to alarm the maid fervant, tor whom he miflook his miftrefs* She came with difficulty up flairs, began to flood im- mediately, and mifcarried in a few hours. She has fince borne feveral children, nor- ever had any ten- dency to mifcarry of any of them. In . XXXIX. 6. GENERATION. 595 In refpeft to the power of the imagination of the male over the form, colour, and fex of the progeny, the following inilances have fallen under my obfer- vation, and may perhaps be found not very unfre- quent, if they were more attended to. I am ac- quainted with a gentleman, who has one child with dark hair and eyes, though his lady and hnnfelf have light hair and eyes ; and their other four child- lenare like their parents. On obferviug this difli- milarity of or.e child to the others he affured me, that he believed it was his own imagination, that produced the difference; and related to me the fol- lowing itory. He faid, that when his lady lay in of her third child, he became attached to a daughter of one of his inferior tenants, and offered her a bribe for her favours in vain; and afterwards a greater bribe, and was equally -unfuccefsful; that the form of this girl dwelt much in his mind for fome weeks, and ihat the next child, which was the dark-ey'd young lady above mentioned, was exceedingly like, in both features and colour, to the young woman \vho refilled his addreiles. To this inihince I muft add, that I have known two families, in which, on account of an intailed eftate in expectation, a male heir was molt eagerly defired by the father; and on the contrary, girls were produced to the feventh in one, and to the ninth in another ; and then they had each of them a fon. I conclude, that the great defire of a male heir by the father produced rather 3 diiagreeable than an agreeable fenfation ; and that his ideas dwelt more on the fear of generating a female, than on the pleafurable fenfationsor ideas of his own male form or organs at the time of copulation, or of the fecre- tion of the femen ; and that hence the idea of the female charader was more prefect to his mind than that of the rnale one ; till at length in defpair of ge- nerating 594 GENERATION. SECT. XXXIX. 7. nerating a male thefe ideas ceafed, and thofe of the male character prefided at the genial hour. 7. Hence I conclude, that the aft of generation cannot exift without being accompanied with ideas, and that a man muft have at that time either a gene- ral idea of his own male form, or of the form of his male organs ; or an idea of the female form, or of her organs; and that this marks the fex, and the pe- culiar refemblances of the child to either parent. From whence it would appear, that the phalli, which were hung round the necks of the Roman ladies, or worn in their hair, might have efTeti in producing a greater proportion of male children; and that the callipsedia, or art of begetting beautiful children, and of procreating either males or females, may be taught by affecting the imagination of the male-parent ; that is, by the fine extremities of the feminal glands imitating the actions of the organs of fenfe either of fight or touch. But the manner of accomplifhing this cannot be unfolded with fufficient delicacy for the public eye; but may be worth the attention of thofe, who are ferioufly interefled in the procreation of a male or female child. Recapitulation • VII. I. A certain quantity of nutritive particles are produced by the female parent before impregna- tion, which require no further digeltion, fecretion, or oxygenation. Such are feen in the unimpregnated eggs of birds, and in the unimpregnated feed-veifels of vegetables. 2. A living filament is produced by the male, which being inferted amidfl thefe firft nutritive parti- cles, is fUmulated into action by them; and in con- fequence of this action, fome of the nutritive parti- cles are embraced, and added to the original living filament ; S£CT. XXXIX. 7. GENERATION. 595 filament ; in the fame manner as common nutrition is performed in the adult animal. 3. Then this new organization, or additional part, becomes ftimulated by the nutritive particles in its vicinity, and fenfation is now fuperadded to irritati- on; and other particles are in confequence embra- ced, and added to the living filament ; as is fcen in the new granulations of fiefh in ulcers. By the power of affociation, or by irritation, the parts already produced continue their motions, and new ones are added by fenfation, as above mention- ed ; and laftly by volition, which laft fenforial power is proved to exift in the fetus in its maturer age, becaufe it has evidently periods of activity and of fleeping ; which laft is another word for a tempora- ry iufpenfion of volition. The original living filament may be conceived to poflefs a power of repulfing the particles applied to certain parts of it, as well as of embracing others, which flirnulate other parts of it ; as thefe powers exifl in different parts of the mature animal ; thus the mouth of every gland embraces the particles or fluid, which fuits its appetency ; and its excretory duel: repulfes thofe particles, which are difagrecable to it. 4. Thus the outline or miniature of the new ani- mal is produced gradually, but in no great length of time ; becaufe the original nutritive particles require no previous preparation by digeftion, fecretion, and oxygenation : but require fimply the feieclion and appofition, which is performed by the lining filament. Mr. Blumenbach fays, that he poflefles a human fetus of only five weeks old, which is the fize of a common bee, and has all the features of the face, every finger, and every toe, complete ; and in which the organs of generation are diftindily feen. P. 76. In another fetus, whofe head was not larger than a pea, the whole of the bafis of the fkull with all its depreilions, GENERATION. SIOT. XXXIX. 7. depreffions, apertures, and procefTes, were marked in the mo'l fharp and diftindt manner, though with- out any offification. Ib. 5. In fome cafes by the nutriment originally do- pofited by the mother the filament acquires parts not exactly firnilar to thofe of the father, as in the pro- du&ion of mules and mulattoes. In other cafes, the deficiency of this original nutriment caufes deficien- cies of the extreme parts of the fetus, which are laft formed; as the fingers, toes, lips. In other cafes, a duplicature of limbs are caufed by the fuper- abundance of this original nutritive fluid, as in the double yolks of eggs, and the chickens from them with four legs and four wings. But the production of other monfters, as thole with two heads, or with parts placed in wrong fituations, feems to arife from the imagination of the father being in lome manner imitated by the extreme veflels of the feminal glands ; as the colours of the fpots on eggs, and the change of the colour of the hair and feathers of ani- mals by domeftication, may be caufed in the fame manner by the imagination ot the mother. 6- The living filament is a part of the father, and has therefore certain propenfnies, or appetencies, which belong to him ; which may have been gradu- ally acquired during a million of generations, even from rhe infancy of the habitable earth ; and which now poifeiTes fuch properties, as would render, by the appofition of nutritious particles, the new fetus exadtiy fimilar to the father ; as occurs in the buds and bulbs of vegetables, and in the polypus, and tsenia or tape-worm. But as the fii ft nutriment is fupplied by the mother, and therefore refembles fuch nutritive particles, as have been ufed for her own nutriment or growth, the progeny takes in part of the likenefs of the mother. Other fimilarity of the excitability, or of the form of the male parent, fuch as '.he broad or narrow (boulders, SECT. XXXIX. 7. GENERATION. 597 fhoulders, or fuch as conftitute certain hereditary difeafes, as icrophula, epilepfy, infanity, have their origin produced in one or perhaps two geneiations; as in the progeny of thole who drink much vinous fpirits; and thofe hereditary propeniities ceafe again, as I have obferved, if one or two ibber generations fucceed ; otherwife the family becomes extinct. This living filament from the lather is alib liable to have its propeniuies, or appetencies, altered :\t the time of its production by the imagination of the male parent; the extremities of the feminal glands imitating the motions of the organs of fenfe ; and thus the fex of the embryon is produced ; which may be thus made a male or a female by affeding the imagination of the father at the time of impreg- nation. See Sedl. XXXIX. 6. 3. and 7. 7. After the fetus is thus completely formed to- gether with its umbilical veflels and placenta, it is now fupplied with a different kind of food, as ap- pears by the difference of coniiftency of the differ- ent parts of the white of the egg, and of the liquor amnii, for it has now acquired organs for digeition or fecretion, and for oxygenation, though they aie as yet feeble ; which can in fome degree change, as well as felcdt, the nutritive particles, which are nou' prefented to it. But may yet be aifected by the deficiency of the quantity of nutrition fupplied by the mother, or by the degree of oxygenation fup- plied to its placenta by the maternal blood. The augmentation of the complete fetus by ad- ditional particles of nutriment is not accomplished by diftention only, but by apportion to every part both external and internal ; each of which acquires by animal appetencies the new addition of the par- tides which it wants. And hence the enlarged paits are kept iimilar to their prototypes, and may be faid to be extended ; but their extenfion muit be conceived only as a neceffary confequence of the enlargement GENERATION. SECT. XXXIX. 7. enlargement of all their parts by apportion of new pai tides. Hence the new apportion of parts is not produced by capillary attraction, becaufe the whole is ex- tended ; whereas capillary attraction would rather tend to bring the fides of flexible tubes together, and nut to diilend them. Nor is it produced by che- mical affinities, for then a folution of continuity would fucceed, as when fugar is diffolved in water ; but it is produced by an animal procefs, which is the confequence of irritation, or fenfation ; and which may be termed animal appetency. This is further evinced from experiments, which have been instituted to fhew, that a living mufcle of an animal body requires greater force to break it, than a fimilar mufcle of a dead body. Which evinces, that befides the attraction of coheiion, which all- matter poifeffes, and befides the chemical attrac- tions of affinities, which hold many bodies together, there is an animal aciheiion, which adds vigour to thefe common laws of the inanimate world. 8. At the nativity of the child it depofits the placenta or gills, and by expanding its lungs ac- quires more plentiful oxygenation from the currents of air, which it murt now continue perpetually to refpire to the end of its Hie ; as it now quits the liquid element, in which it was produced, and like 'the tadpole, when it changes into a frog, becomes an aciial animal. 9. As the habitable parts of the earth have been, and continue to be, perpetually increafing by the production of fea-fhells and corallines, and by the recrements of other animals, and vegetables ; fo from the beginning of the exiflence of this terraqueous fjlobe, the animals, which inhabit it, have conftant- fy improved, and are dill in a flare of progreffive iajproveinept. This SECT. XXXIX. 8. GENERATION. 599 This idea of the gradual generation of all things feems to have been as familiar to the ancient philo- fophers as to the modern ones ; and to hav7e given i ife to the beautiful hieroglyphic figure of the ^TOV «ov, or fir II great egg, produced by NIGHT, that is, whofe origin is involved in obfcuritya and animated by E£O-, that is, by DIVINE LOVE j from whence proceeded all things which exift. Conclufton. VIIL i. CAUSE AND EFFECT may be confidered as the progreflion,or fucceflive motions, of the parts of the great fyftem of Nature. The ilate of things at this moment is the effect of the (late of things, which exiiled in the preceding moment; and the caule of the ftate of things, which fhall exiit in the next moment. Thefe caufes and effects may be more eafily com- prehended, if motion be conlidered as a change of the figure of a group of bodies, as piopofed in Seel:. XIV. 2. 2. inafmuch as our ideas of vilible or tan- gible objects are more diflinct, than our abilracled ideas of their motions. Now the change of the configuration of the fyrlem of nature at this mo- ment niu ft be an efFect of the preceding configura- tion, for a change of configuration cannot exift without a previous configuration ; ?nd the proxi- mate caufe of every effect mud immediately precede that effect. For example, a moving ivory ball could not proceed onwaids, unlefs it had previously began to proceed ; or unlefs an impulfe had been previ- oufly given it ; which previous motion or impulfe conttitutes a part of the laft lunation of things. As the effects produced in this moment of time become caufes in the next, we may confider the pro- grefilve motions of objects as a chain of caufes only; GENERATION. S*CT. XXXIX. 8. / only; whofe firft link proceeded frorn the great Crea- tor, and which ha\e exifted from the beginning of the cieated univerfe, and are perpetually proceeding. 2. Thefe caufes may be conveniently divided into- two kinds, efficient and inert caufes, according with the two kinds of entity fuppofed to exifl in the na- tural world, which may be termed matter and fpirit, as propofed in Sect. I. and further treated of in Sect. XIV. The efficient caufes of motion, or new configuration, confift either of the principle of gra- vnatioa, which a6tuares the fun and planets ; or of the principle of particular gravitation, as in elec- tricity, magnetifm, heat ; or of the principle of che- mical affinity, as in combuftion, fermentation, com- bination ; or of the principle of organic life, as in the contraction of vegetable and animal fibres. The inert caufes of motion, or new configuration, con- fift of the parts of matter^ which are introduced tvithin the fpheres of activity of the principles above tlcfcribed. Thus, when an apple falls on the ground, the principle of gravitation is the efficient caufe, and the matter of the apple the inert caufe. If a bar of iron be approximated to a magnet, it may be termed the inert caufe of the motion, which brings thcfe two bodies into contact; while the magnetic principle may be termed the efficient caufe. In the lame manner the fibres, which conftitute the retina, may be called the inert caufe of the motions of that 0rg*n in vifion, while the fenforial power may be termed the efficient caufe. 3. Another moie common diftiibution of the per-* peural chain of caufes and effedts, which conftitute the motions, or changing configurations, of the na- tural world, is into active and paflive. Thus, if a ball in motion impinges againft another ball at reft, and communicates its motion to it, the former ball is faid to act, and the latter to be a6led upon. In this fenfe of the words a ningnet is faid to attract iron ; SECT. XXXIX 8. GENERATION. 601 iron ; and the prick of a fpur to ftimulate a horfe inio exertion ; fo that in this view of the works of nature all things may be faid either limply to exift, or to exift as caufes, or to exift as effects ; that is, to exift either in an a&ive or paflive itate. Ihis diftribution of objects, and their motions, or changes of pofition, has been found fo conveni- ent for the purpofes of common li:e, that on this foundation refts the whole conftru&ion or theory of language. The names of the things thernfelves are termed by grammarians Nouns, and their modes of exiftence are termed Verhs The nouns are di- vided into fubftantives, which denote the principal things fpoken of; and into adjectives, which denote forae circumftances, or lefs kinds of things, belong- ing to the former. The verbs are divided into three kinds, fuch as denote the exiflence of things fimply, as, to be ; or their exiftence in an a&Ive ftate, as, to eat ; or their exiftence in a paflive ftate, as, to be eaten. Whence it appears, that all languages con- fift only of nouns and verbs, with their abbreviati* ons for the greater expedition of communicating our thoughts ; as explained in the ingenious work of Mr. HorneTooke, who has unfolded by a fingle flafh of light the whole theory oF language, which has fo long lain buried beneath the learned lumber of the fchools. Diverfions of Purley. Johnfon. Lon- don. 4. A third divifion of caufes has been into proxi- mate and remote ; thefe have been much fpoken of oy the writers on medical fubjecls, but without fuf- ficient precifion. If to proximate and remote caufes \ve add proximate and remote effecls, we fhall in- clude four links of the perpetual chain of caufation ; which will be more convenient for the difculllon of many philofophical fubjecls. Thus if a particle of chyle be applied to the mouth of a lafteal veffel>it may be termed the remote caufe of 6os GENERATION. SECT. XXXIX. 8. of the motions of the fibres, which Oompofe the mouth of that lacteal veffel ; the fenforial power is the proximate caufe ; the contraction of the fibres of the mouth of the veffel is the proximate effect ; and their embracing the particle of chyle is the re- mote effect ; and thefe.four links of caufation con- f lit me abforption. Thus when we attend to the rifing fan, firft the yellow rays of light ftimulate the fenforial power refiding in the extremities of the optic nerve, this is the remote caufe. 2. The fenforial power is ex- cited into a (late of activity, this is the proximate caufe. 3. The fibrous extremities of the optic nerve arc contracted, this is the proximate effect. 4. A pleafsrable or painful fenfation is produced in con- fequencc of the contraction of thefe fibres of the optic nerve, this is the remote effect ; and thefe four links of the chain of caufation conflitute the fenfi- live idea, or what is commonly termed the fenfa- tion of the rifing fun. 5. Other caufcs have been announced by medi- cal writers under the names of caufa procatarctica, and caufa proegumina, and caufa fine qu3. non. All which are links more or lefs diflant of the chain of remote caufes. To thefe mufl be added the final caufe, fo called by many authors, which means the motive, for the accomplifhment of which the preceding chain of caufes was put into acYion. The idea of a final caufe, therefore, includes that of a rational mind, which employs means to effect its purpofes ; thus the deiire of preferving himfelf from the pain of cold, which he has frequently experienced, induces the favage to conftrudt his hut ; the fixing flakes into the ground for walls, branches of trees for raf- ters, and turf for a cover, are a feries of fucceffive voluntary exertions ; which are fo many means to produce a certain effect. This effect of preferving himfelf SECT. XXXIX. 8. GENERATION. 603 himfelf from cold, is termed the final caufe ; the conftru&ion of the hut is the remote effect ; the ac- tion of the mufcular fibres of the man, is the prox- imate effect ; the volition., or activity of deiire to preferve himfelf from cold, is the proximate caufe; and the pain of cold, which excited that defire, is the remote caufe. 6. This perpetual chain of caufes and effecls, whofe firft link is rivetted to the throne of GOD, divides itfelf into innumerable diverging branches, which, like the nerves arifing from the brain, per- meate the molt minute and moft remote extremities of the fyftem, diffafing motion and fenfation to the whole. As every caufe is fuperior in power to the effect, which it has produced, fo our idea of the power of the Almighty Creator becomes more ele- vated and fublime, as we trace the operations of na- ture from caufe to caufe, climbing up the links of thefe chains of being, till We afcend to the Great Source of all things, Hence the modern difcoveries in chemiflry and in geology, by having traced the caufes of the com- binations of bodies to remoter origins, as well as thofe in aftronomy, which dignify the prefent age, contribute to enlarge and amplify our ideas of the power of the Great Firft Caufe. And had thofe ancient philofophers, who contended that the world was formed from atoms, afcribed their combinations to certain immutable properties received from the hand of the Creator, fuch as general gravitation, chemical affinity, or animal appetency, inftead of afcribing them to blind chance ; the doctrine of atoms, as constituting or compoiing the material world by the variety of their combinations, fo far from leading the mind to atheifm, would ftrengthen the demonftration of the exigence of a Deity, as the firft caufe of all things ; becaufe the analogy re- fulting from our perpetual experience of caufe and VOL. I. Rr effed ££NERATICfN. SECT. XXXIX. «. efle& xvould have thus been exemplified through univerfal nature. The heavens declare the glory of GOD, and the fr~ mament foewetk his handy work! One day telleth ano- ther, and one night certijietk another ; they have neither ffeechnor language, yet their voice is gone forth into all lands, and their words into the ends of the world. Manifold are thy works, O LORD ! in wifdom kaji thou wade them all. Pfal. xix. civ, SECX SLCT. XL. i. OCULAR SPECTRA. SEC T. XL. On the OCUIAR SPECTRA of Light and Colours, by Dr. R. W. Darwin, of Shrevvfbury. Re- printed by Permiflion, frtfrn the Philofophical Tranfadions, Vol. LXXVI. p. 3*3. Speclra of four kinds. I . Activity of the retina in vi- fwn. 2. Speflrafrom def eft of fenfibility. 3. Spec- tra from exccfs of fenfibility. 4. Of dire ft ocular Spedra. 5. Greater Jlimulus excites the retina into fpafmodic aclion. 6. Of reverfe ocular fpeclra. 7. Greater flimulus excites the retina into various fuc- cejjiye fpafmodic aclions. 8. Into fixed fpafmodic atJion. 9. Into temporary paralyjis. 10. Mifcef- laneoiis remarks ; i. DirecJ and reverfe fpeclra at the fame time. Afpeflral halo. Rule to predeter- mine the colours of fpeflra. 2. Variation of fpeftra from extraneous light. 3. Variation of fpeflra in number, figure, and remij/ion. 4. Circulation of the b/oo i in the eye is vijtble. 5. A new way of mag- nifying objects. Conclufion. WHEN any one has long and attentively looked at a bright object, as at the fetting fun, on cloiing his eyes, or removing them, an image, which re- fembles in form the objeft he was attending to, continues fome time to be vifible ; this appearance- in the eye we fhall call the ocular fpe&rum of that objetl. Thefc ocular fpe6^ra are of four kinds : ift, Such as are owing to a lefs fenfibility of a defined pare of the retina ; or fpeflra from defeB of fenfibility. zd, Such as are owing to a greater fenfibility of a R r 2 defined 6o6 OCULAR SPECTRA. SECT. XL, i. defined part of the retina ; or fpefira from excefs of fallibility. 3d, Such as referable their object in its colour as well as ioi m ; which may be termed direft ocular ffe&ra. 4th, Such as are of. a colour con- trary to that of their object ; which may be termed rewrfe ocular fpeftra. The laws of light have been moft fuccefsfully ex- plained by the great Newton, and the perception of vifible objects has been ably investigated by the in- genious Dr. Berkeley and M. Malebranche ; but thefe minute phenomena ot vifion have yet been thought reducible to no theory, though man) philo- fophers have employed a conliderable degree of at- tention upon them : among thefe are Dr. Jurin, at the end of Dr. Smith's Optics; M. jEpinus, in the Mov. Com. Petropol. V. 10, ; M. Beguelin, in the Berlin Memoires, V. II 1771 , M. D'Arcy, in the Hiftoire de 1'Acad. des Scienc. 1765 ; M. de la Hire; and laflly, the celebrated M. de Button, in the Memoires de 1'Acad des Seien. who has termed them accidental colours, as if fubje&ed to no eftab- Jiflied laws, Ac. Par. 1743. M p. 215. I muft here apprize the reader, that it is very dif- ficult for different people to give the fame names to various fhades of colouis ; whence, in the following pages, fomething muft be allowed, if on repeating the experiments the colours here mentioned mould not accurately correfpond with his own names of them. I. A&faity of the Retina in Vifion* FROM the fubfequent experiments it appears, that the retina is in an a£iive not in a paflive Hate during the exiftence of thefe ocular fpe&ra; and it is thence to be concluded, that all viiion is owing to the ac- tivity of this organ. i. Place Ecr.XL. j. OCULAR SPECTRA. 697 1. Place a piece of red filk, about an inch in di- ameter, as in plate i, at Seel. III. i, on a fheet of white paper, in a ftrong light ; look fteadily upon it from about the dilhinceof half a yard f}r a mi. nute; then doling your eyelids cover them with your hands, and a green fpeitrum will be feen in your eyes, refembiing in form the piece of red filk : after foine time, this fpeclrum will difappear and fhortly re-appear ^ and this alternately three or four times, if the experiment is well made, till at length it vanifhes entirely. 2. Place on a Iheet of white paper a circular piece of blue filk, about four inches in diameter, in the funmine ; cover the center of this with a circular piece of yellow filk, about three inches in diameter j and the center of the yellow filk with a circle of pink filk, about two inches in diameter; and the center of the pink filk with a circle of green filk, about one inch in diameter ; and the centre of this with a circle of indigo, about half an inch in dia- meter ; make a fmall fpeck with ink in the very centre of the whole, as in plate 3, at Seel. III. 3. 6. ; look iteadily for a minute on this central fpot, and then doling your eyes, and applying your hand at about an inch diftance before them, fo as to prevent too much or too little light from patting through the eyelids, you will fee the moft beauti- ful circles of colours that imagination can conceive, which are molt reieinbled by the colours occationed by pouring a drop or two of oil on a Hill lake in a bright day ; but thefe circular irifes of colours are not only different from the colours of the filks above mentioned, but are at the fame time perpetually changing as long as they exift. 3. When any one in the dark preflfes either cor- ner of his eye with his ringer, and turns his eye away from his finger, he will fee a circle of colours like thofe in a peacock's tail: and a fudden flafh of light 608 OCULAR SPECTRA. SECT. XL. i, light is excited in the eye by a ftroke on it. (New- ton's Opt. Q.^16.) 4. When any one turns round rapidly on one foot, till he becomes dizzy, and falls upon the ground, the fpe&ra of the ambient objects continue to prefent themfelves in rotation, or appear to li- brate, and he feems to behold them for fome time ftill in motion. From all thefe experiments it appears, that the fpe&ra in the eye are not owing to the mechanical impulfe of light impreffed on the retina, nor to its chemical combination with that organ, nor to the abforption and emiflion of light, as is obferved in many bodies ; for in all thefe cafes the fpectra muft either remain uniformly, or gradually diminifh; and neither their alternate prefence and evanefcence as in the firft experiment, nor the perpetual changes of their colours as in the fecond, nor the flafh of light or colours in the prefTed eye as in the third, nor the rotation or libration of the fpeclra as in the fourth, could exift. It is noi abfurd to conceive, that the retina may be ftimulated into motion, as well as the red and white mufcles which ferm our limbs and veffels ; iince it conlifts of fibres, like thofe, intermixed with its medullary fubftance. To evince this ftru&ure, the retina of an ox's eye was fufpended in a glafs of warm water, and forcibly torn in a few places ; the edges of thefe parts appeared jagged and hairy, and did not contract, and become fmooth like fimple mucus, when it is diftended till it breaks ; which fhews that it confifts of fibres ; and that its fibrous conduction became Hill more diftindt to the fight, by adding fome cauftic alkali to the water, as the adhering mucus was firft eroded, and the hair-like fibres remained floating in the veflel. Nor docs the degree of tranfparency of the retina invalidate the evidence of its fibrous ftrudure, fince Leeuwenhoek has SECT. XL. 2. OCULAR SPECTRA. 609 has fhewn that the cryftallinc humour itfelf confifts of fibres* (Arcana IS at urse, V. i. p. 70.) Hence it appears, that as the mufcles have larger fibres intermixed with a larger quantity of nervous medulla, the organ of vifion has a greater quantity of nervous medulla intermixed with fmaller fibres ; and it is probable that the locomotive mufcles, as well as the vafcular ones, of microfcopic animals have much greater tenuity than thcfe of the retina. And bcfides the iimilarlaws, which will be fhewn in this paper to govern alike the actions of the re- tina and of the mufcles, there are many other ana- logies which exift between them. 1 hey are both originally excited into action by irritations, both aft nearly in the fame quantity of time, are alike ftrengthened or fatigued by exertion, are alike pain- ful if excited into action when they are in an in- flamed ftate, are alike liable to paralyiis, and to the torpor of old age. II, OF SPECTRA FROM DEFECT OF SENSIBILITY. The retina is not fo eafily excited into aft'wn by lefs irri- tation after having been lately fttbje&ed to greater. I. WHEN any one paffes from the bright daylight into a darkened room, the irifes of his eyes expand themfehes to their utmoft extent in a few feconds of time; but it is very long before the optic nerve,, after having been ftimulated by the greater light of the day, becomes fenfible of the lefs degree of it in the room ; and, if the room is not too obfcure, the irifes will again contract themfelvcs in foiue degree, as the fenfibility of the retina returns. 2. Place about half an inch fquare of white paper on a black hat, and looking fteadily on the center of it for a minute, remove your eyes to a fheet of white 6co OCULAR SPECTRA. SECT. XL. a, white paper ; and after a fecond or two a dark fquare will be feen on the white paper, which will conti- nue fome time. A iimilar dark fquare will be feen in the clofed eye., if light be admitted through the eyelids. So after looking at any luminous object of a fmall fize, as at the fun, for a fliort time, fo as not much to faiigue the eyes, this part of the retina becomes lefs fen fib le to fmaller quantities of light ; hence, when the eyes are turned on other lefs luminous parts of the fky, a dark fpot is feen refembling the fliape of the fun, or other luminous object which we laft beheld. This is the fource of one kind of the dark-coloured mufca vplitantes. If this dark fpot lies above the cepter of tlfe eye, we turn our eyes that way, expecting to bring it into the center of the eye, that we may view it more distinctly ; and in this cafe the dark fpectrum feems to move up- wards. If the dark fpectrum is found beneath the centre of the eye, we purfue it from the fame mo- tive, and it fee ins to move downwards. This has given rife to various conjectures of fomething float- ing in the aqueous humours of the eyes ; but who- ever, in attending to thefe fpots, keeps his eyes •unmoved by looking fteadily at the corner of a cloud, at the fame time that he obferves the dark fpectra, will be thoroughly convinced, that they have no motion but what is given to them by the movement of our eyes in purfuit of them. Si>me- times the form of the fpectrurn, when it has been received from a circular luminous body, will be- come oblong ; and fometimes it will be divided into two circular fpectra, which is not owing to our changing the angle made by the two optic axifes, according to the diftance of the clouds or other bodies to which the fpectrum is fuppofed to be contiguous, but to other caufes mentioned in ISo. Xo • J XL.a. OCULAR SPECTRA. / X. 3. of this fedtion. The apparent fize of U alfo be variable according to its fuppofed diftance. As thefe fpe&ra are more eafily obfervable when ( our eyes are a little weakened by fatigue, it has frequently happened, that people of delicate confti- tutions have been much alarmed at them, fearing a beginning decay of their light, and have thence fallen into the hands of ignorant oculifts ; but I be- lieve they never are a prelude to any other difeafe of the eye, and that it is from habit alone, and our want of attention to them, that we do not fee them on all objects every hour of our lives. But as the nerves of very weak people lofe their fen(i- bility, in the fame manner as their mufcles lofe their activity, by a fmall time of exertion, it frequently happens, that fick people in the extreme debility of fevers are perpetually employed in picking fome- thing from the bed-clothes, occafioned by their mif- taking the appearance of thefe mufca wlitantes in their eyes. Benvenuto Celini, an Italian artilt, a man of ftrong abilities, relates, that having paifed the whole night on a diftant mountain with fome companions and a conjurer, and performed many ceremonies to raife the devil, on their return in the morning to Rome, and looking up when the fun began to rife, they faw numerous devils run on tfee tops of the houfes, as they pafled along \ fo much were the fpectra of their weakened eyes magnified by fear, and made fubfervient to the purpofes of fraud or fuperftition. (Life of Ben. Celini.) 3. Placeafquare inch of white paper on a large piece of ftraw-coloured filk; look fleadily fome time on the white paper, and then move the centre of your eyes on the filk, and a fpectrum of the form of the paper will appear on the (ilk, of a deeper yellow than the other part of it : for the central part of the retina, having been fome time expofed to the ftimulus of a greater quantity of white light, is 6x* OCULAR SPECTRA. SECT. XL. $, is become lefs fenfible to a fmaller quantity of it, and therefore fees only the yellow rays in that pars of the ftraw-coioured lilk. Facts fimilar to thefe are obfervable in ottar parts of our fyftem : thus* if one hand be made warm* arid the other expofed to the cold, and then both of them intrncffed in fubtepid water, the water is perceived warm to one hand, and cold to the other ; and we are not able to hear weak founds for forne time after we have been expofed to loud ones ; and we feel a chillinefs on coming into an atmof- phere of temperate warmth, after having been fome time confined in a very warm room : and he,,ce the ftotnaeh, and other organs of digeilion, of thofe who have been habituated to the greater ftimulus of fpi- fituous liquor, are not excited into their due action by the left ftimulus of common food alone ; of which the immediate conference is indigeftion and hypochondriacifm- III. OF SPECTRA FROIvi EXCESS OF SENSIBILITY, The retina is more eafity. excited into a&'wn by greater irritation after having been lately fitbjefted to lefs. f, IF the eyes are clofed, and covered perfectly With a hat, for a minute or two, in a bright day j on femoving the' hat, a1 red or crirufon light Js feen through the eyelids, la this experiment the retina, after being fome time kept in the dark, becomes fo fenfible to a fmall quantity of light., as to perceive ciiiiinctly the greater quantity of red rays than of others \vhich pafs through the eyelids* A limilar toioufed light is feen to pafs through the edges of the fingers, when the open hand is oppofed to the fiame of a candle, 2. If SECT. XL. 3. OCULAR SPECTRA. 615 2. If you look for fome minutes ileadily on a window in the beginning of the evening twilight, or in a dark day, and then move your eyes a little, fo that thofe parts of the retina, on which the dark frame-work of the window was delineated, may now fall on the glafs part of it, many luminous lines, reprefenting the frame-work, will appear to lie acrofs the glafs panes : for thofe parts of the retina, which were before Icafl ftimulated by the dark frame-work, are now more fenfible to light than the other parts of the retina which were expofed to the more luminous parts of the window. 3. M^ke with ink on white paper a very black fpot, about half an inch in diameter, with a tail about an inch in length, fo as to reprefent a tad- pole, as in plate 2, at Sec~l. III. 8. 3. ; look fteadily for a minute on this fpot, and, on moving the eye a little, the figure of the tadpole will be feen on the white part of the paper, which figure of the tad- pole will appear whiter or more luminous than the other parts of the white paper ; for the part of the retina on which the tadpole was delineated, is now more fenfible to light than the other parts of it, which were expofed to the white paper. This ex- periment is mentioned by Dr. Irwin, but is not by him afcribed to the true caufe, namely, the greater fenfibility of that part of the retina which has been expofed to the black fpot, than of the other parts which had received the white field of paper, which is put beyond a doubt by the next experiment. 4. On clofing the eyes afier viewing 'the black fpot on the white paper, as in the foregoing expe- riment, a red fpot is fecn of the form of the black fpot : for that part of the retina, on which the black fpot was delineated, being now more fenfible to light than the other parts of it, which were more expofed to the white paper, is capable of perceiv- ing the red rays which penetrate the eyelids. If this. 614 Q GUI, A 11 SPECTRA. StcrP XL. j, this experiment be made by the light of a tallow candle, the ipot will be yellow in (lead of red ; fur tallow candles abound much' with yellow light, which pafles in greater quantity and force through the eyelids than blue light ; hence the difficulty of diflinguifhing blue and green by this kind of candle light. 1 he colour of the fpeclrtim may poffibly vary in the daylight, according to the different co- Iptir of the meridian or the morning or evening light. M. Bcguelin, in the Berlin Memoires, V. IL 1771, obie-rves, that, when he held a book, fo that the fun fhone upon his half-clofed eyelids, the black letters, \vhich he had long infpedlcd, became red, which mud have been thus occaiioncd- 1 hole parts of the retina which had received for fome time the black letters, were fo much more fenfible than thofe parts which had been oppofed to the white paper, that to the former the red light, which paffed through the eyelids, was perceptible. There is a finiilar (lory told, 1 think, in M. de Voltaire's Hiftorical Works, of a Duke of Tufcany, who was playing at dice with the general of a foreign army, and, believing he faw bloody fpots upon the dice, portended dreadful events, and retired in confufion. The obferver, afier looking for a minute on the black fpots of a die, and carelefsly clpfing his eyes, on a bright day, would fee the image of a die with red fpots upon it, as above explained. 5. On emerging from a dark cavern, where we liave long continued, the light of a bright day be- comes intolerable to the eye fora confiderable time, owing to the excefs of fenfibility exifting in the eye, af.er having been long expofed to little or no ftimuT lus. This occafions us immediately to contract the iris to its fmalleft aperture, which becomes again gradually dilated, as the retina becomes accuflomed to the greater ftimulus of the daylight. The S*CT. XL. 3. OCULAR SPECTRA. 61$ The twinkling of a bright ftar, or of a diftant candle in the night, is perhaps owing to the lame caufe. While we continue to look upon thcfe lu- minous objects, their central parts gradually appear paler, owing to the decreafing fenfibili.y of ihe part of ihe retina expofcd to their light ; whilft, at ihe fame time, by the unfteadinefs of the eye, the edges of them are perj etually falling on parts of the re- tina that were jufl before cxpofed to the darknefs of the uighr, and therefore tenfold more fenfible to light than the fart on which the i at* or candle had I cen for fome time delineated. 1 his pains the eye in a fimilar manner as when we come fuddcnly from a dark room into bright day-light, and gives the appearance of bright fcintillations. Hence the flars twinkle moft when ihe night is darkeft, and do not twinkle through telefcopes, as cbferved by Muficherbroeck ; and it will afterwards be feen why this twinkling is fome- times of different colours when the object is very bright, as Mr. Melvill obferved in looking at Sirius. For the opinions of others on this fubjecl, fee Dr. Prieftley's valuable Hiftory of Light and Colours, p. 494. Many facls obfervable in the animal fyftem are fimilar to thefe ; as the hot glow occafioned by the ufual warmth of the air, or our clothes, on coming out of a cold bath ; the pain of the fingers on ap- proaching the fire after having handled fnow; and the inflamed heels from walking in fnow. Hence thofe v\ho have been expofed to much cold have died on being brought to a fire, or their limbs have become fo much inflamed as to mortify. Hence much food or wine given fuddenly to thofe who have almoft perifhed by hunger has deftroyed them ; for all the organs of the famifhed body are now become fo much more irritable to the ftimulus of food and wine, which they have long been deprived of, that inflammation \ OCULAR SPECTRA. SECT. XL. 4 inflammation is excited, which terminates in gan- grene or fever. IV. OF DIRECT OCULAR SPECTRA. A quantity of Jlimulus fomewhat greater than natural excites the retina into fpafmodic adion, which ceafes in> ajewfecondf. A certain duration and energy of the ilimulus of light and colours excites the perfe6l a6tion of the retina in viiion ; for very quick motions are imper- ceptible to us, as well as very flow ones, as the whirling of a top, or the fhadow on a fun-dial. So perfe6t darknefs does not affedl the eye at all ; and excels of light produces pain, not viiion. I. When a fire-coal is whirled round in the dark, & lucid circle remains a confiderable time in die eye ; and that with fo much vivacity of light, that it is mi (taken for a continuance of the irritation of the objeft. In the fame manner, when a fiery me- t'Cor fhoots acrofe the night, it appears to leave a Jong lucid train behind it, part of which, and per- haps fometimes the whole, is owing to the conti- nuance of the a6lion of the retina after having been thus vividly excited. This is beautifully illuflrated by the following experiment : fix a paper fail, three or four inches in diameter, and made like that of a fmoke jack, in a tube of pafteboard ; on looking through the tube at a diftant profpedl, fome dis- iornted parts of it will be feen through the narrow intervals between the fails ; but as the fly begins to fevolve, thefe intervals appear larger ; and when it revolves quicker, the whole profpeft is feen quite as diftinft as if nothing intervened, though lefs lu- minous* 2. Look SECT. XL. 4. OCULAR SPECTRA. 61; 2. Look through a dark tube, about half a yard long, at the area of a yellow circle of half an inch diameter, lying upon a blue area of double that di- ameter, for half a minute ; and on clofing your eyes the colours of the fpectrum will appear fimilar to the two areas, as in fig. 3. ; but if the eye is kept too long upon them, the colours of the fpectrum will be the reverfe of thofe upon the paper, that is, the internal circle will become blue, and the ex- ternal area yellow ; hence fome attention is required in making this experiment. 3. Place the bright flame of a fpermaceti candle before a black object in the night ; look fteadilyat it for a fhort time, till it is obferved to become fome- what paler ; and on clofing the eyes, and covering them carefully, but not fo as to comprefs them, the image of the blazing candle will continue diftindtly to be vifible. 4. Look fteadily, for a fhort time, at a window in a black day, as in Exp. 2. Se&.III. and then clofing your eyes, and covering them with your hands, an exaft delineation of the window remains for fome time vifible in the eye. This experiment requires a little practice to make it fucceed well ; lince, if the eyes are fatigued by looking too long on the win- dow, or the day be too bright, the luminous parts of the window will appear dark in the fpectrum, and the dark parts of the frame-work will appear lumin- ous, as in Exp. 2. Sect. III. And it is even diffi- cult for many, who firft try this experiment, to perceive the fpectrum at all ; for any hurry of mind,, or even too great attention to the fpectrum itfelf, will difappoint them, till they have had a little ex- perience in attending to fuch finall fenfations. The fpectra defcribed in this fedtion, termed direct ocular fpectra, are produced without much fatigue of the eye ; the irritation of the luminous object be- ing foon withdrawn, or its quantity of light being VOL. I, S s not 6i8 OCULAR SPECTRA. SECT. XL. 5 not fo great as to produce any degree of uneafinef^. in the organ of vifion ; which diftinguifhes therri from the next clafs of ocular fpectra, which are the confcquence of fatigue. Thefe direct fpectra are beft obferved in fuch c ire urn fiances that no light, but what comes from the object, can fall upon the eye ; as in looking through a tube, of half a yard long, and an inch wide, at a yellow paper on the fide of a room, the direct fpectrum was eafily pro- duced on clofing the eye without taking it from the tube; but if the lateral light is admitted through the eyelids, or by throwing the fpectvum on white paper, it becomes a reverfe fpectrum, as will be explained below. The other fenfes alfo retain for a time the impref- fions that have been made upon them, or the ac- tions they have been excited into. So if a hard body is prefled upon the palm of the hand, as is practifed in tricks of legerdemain, it is not eafy to diftinguifh for a few feconds whether it remains or is removed ; and taftes continue long to exift vividly in the mouth, as the fmoke of tobacco, or the tafte of gentian, after the fapid material is withdrawn. V. A quantity of Jlimulus fomewhat greater than ikt lajl mentioned excites the retina into ffafmodic aflion, which ceafes and recurs alternately. I. ON looking for a time on the fetting fun, fo as not greatly to fatigue the fight, a yellow fpectrum is feen when the eyes are clofed and covered, which continues for a time, and then difappears and re- curs repeatedly before it entirely vanifhes. This yellow fpectrum of the fun when the eyelids are opened becomes blue ; and if it is made to fall on the green grafs, or on other coloured objects, it varies SECT. XL. 6. OCULAR SPECTRA, 619 varies its own colour by an intermixture of theirs, as will be explained in another place. 2. Place a lighted fpermaceti candle in the night about one foot from your eye, and lookfleadily on the centre of the flame, till your eye becomes much more fatigued than in Sect. IV. Exp. 3. ; and on clofing your eyes a rcddifh fpectrum will be per- ceived, which will ceafe and return alternately. The action of vomiting in like manner ceafes, and is renewed by intervals, although the emetic drug is thrown up with the firft effort : fo after-pains con- tinue fome time after parturition; and the alternate pulfations of the heart of a viper are renewed for fome time after it is cleared from its blood. VI. OF REVERSE OCULAR SPECTRA. The retina, after having been excited into aftion by a Jlimulus fomewhat greater than the lajl mentioned, falls into oppofite fpafmodic aflion. THE actions of every part of animal bodies may be advantageoufly compared with each other. This ftrict analogy contributes much to the investigation of truth ; while thofe loofer analogies, which com- pare the phenomena of animal life with thofe of chemiftry or mechanics, only ferve to miilead our inquiries. When any of our larger mufcles have been in long or in violent action, and their antagonifts have been at the fame time extended,as foon as the adlion ot the former ceafes, the limb is ftretched the contrary way for our eafe, and a pandiculation or yawning takes place. By the following obfervation it appears, that a iimilar circumftance obtains in the organ of vifion ; S s 2 after 620 OCULAR SPECTRA. SEcf . AL. 6. after it has been fatigued by one kind of action, it fpontaneouily falls into the oppofite kind. i. Place a piece of coloured filk, about an inch in diameter, on a fheet of white paper, about half a yard from your eyes ; look fteadily upon it for a minute ; then remove your eyes upon another part of the white paper, and a fpedtrum will be feen of the form of the filk thus infpe&cd, but of a colour oppofite to it. A fpectruui nearly fimilar will ap- pear if the eyes are clohd, and the eyelids fhaded by approaching the hand near them, fo as to permit fome, but to prevent too much light falling on them. Red filk produced a green fpe&rum. Green produced a red one. Orange produced blue. Blue produced orange. Yellow produced violet. Violet produced yellow. That in thefe experiments the colours of the fpec- tra are the reverfe of the colours which occafioned them, may be feen by examining the third figure in Sir Ifaac Newton's Optics, L. II. p. i, where ihofe thin laminae of air, which reflected yellow, tranf-' mined violet ; thofe which reflected red, tranfmitted a blue green ; and foof the reft, agreeing with the experiments above related. 2. Thefe reverfe fpe&ra are fimilar to a colour, formed by a combination of all the primary colours except that with which the eye has been fatigued in making the experiment : thus the reverfe fpedruni of red muft be fuch a green as would be produced by a combination of all the other prifmatic colours. To evince this fact the following fatisfactory expe- riment was made. The prifmatic colours were laid on a circular pafteboard wheel, about four inches in diameter, in the proportions defcribed in Dr. Prieft ley's Hiftory of Light and Colours, pi. iz. fig. 83 excep SECT. XL. 6. OCULAR SPECTRA. 621 except that the red compartment was entirely left out, and the others proportionably extended fo as to complete the circle. Then, as the orange is a mixture of red and yellow, and as the violet is a mixture of red and indigo, it became neccflary 10 put yellow on the wheel inftead of orange, and indigo inftead of violet, that the experiment might more exactly quadrate with the theory it was de- figned to eftabliih or confute ; becaufe in gaining a green fpcctrum from a red object, the eye is fup- pofed to have become infenfible to red light. This wheel, by means of an axis, was made to whirl like a top ; and on its being put in motion, a green co- lour was produced, correfponding with great exact- nefs to the reverfe fpedtrum of red. 3. In contemplating any one of thefe reverfe fpec- tra in the clofed and covered eye, it difappears and re-appears feveral times fucceflively, till at length it entirely vanifhes, like the direct fpectra in Sect. V.; but with this additional circumftance, that when the fpectrum becomes feint or evanefcent, it is inftantly Tevivcd by removing the hand from before the eye- lids, fo as to admit more light : becaufe then not only the fatigued part of the retina is inclined fpon- taneoufly to fall into motions of a contrary direc- tion, but being (till fenfible to all other rays of light, except that with which it was lately fatigued, is by thefe rays at the fame time Simulated into thofe motions which form the reverfe fpeftrum. From thefe experiments there is rcafon to con- clude, that the fatigued part of the retina throws itfelf into a contrary mode of action, like ofcitation or pandiculation, as foon as the ftimulus which has fatigued it is withdrawn ; and that it ftill remains fenfible, that is, liable to be excited into action by any other colours at the fame time, except the co- lour with which it has been fatigued, VII. The 622 OCULAR SPECTRA. Seer. XL. VII. Tfe r£//>fl tf//*r having been excited into aflion by • a Jlimulus fomewhat greater than the lajl mentioned falls into various fuccejfive fpafmodic aflions. 1. ON looking at the meridian fun as long as the eyes can well bear its brightnefs, the difk firft be- comes pale, with a luminous crefcent, which feems to librate from one edge of it to the other, owing to the unfteadinefs of the eye ; then the whole phafis of the fun becomes blue, furrounded with a white halo ; and on doling the eyes, and covering them with the hands, a yellow fpectrum is feen, which in a little time changes into a blue one. M. de la Hire obferved, after looking at the bright fun, that the impreflion in his eye firft affumed a yellow appearance, and then green, and then blue ; and wifhes to afcribe thefe appearances to fome affection of the nerves. (Porterfield on the eye, Vol. I* P-343-) 2. After looking fteadily on about an inch fquare of pink filk, placed on white paper, in a bright funfhine, at the diftance of a foot from my eyes, and clofing and covering my eyelids, the fpcdtrum of the lilk was at firft a dark green, and the fpectrum of the white paper became of a pink. The fpec- tra then both difappeared ; and then the internal fpectrum was blue ; and then, after a fecond difap- pearance, became . yellow, and laftly pink, whilft the fpectrum of the field varied into red and green. Thefe fucceflions of different coloured fpectra were not exactly the fame in the different experi- ments, though obferved, as near as could be, with the fame quantity of light, and other fimilar cir- cumftanccs ; owing, I fuppofe, to trying too many experiments at a time ; fo that the eye was not quite free from the fpectra of the colours which were pre- vioufly attended to. The ECT. XL. 8. OCULAR SPECTRA. 623 The alternate exertions of the retina in the pre- ceding fection refembled the ofcitation or pandicu- lation of the mufcles, as they were performed in directions contrary to each other, and were the con- fequence of fatigue rather than of pain. And' in this they differ from the fucceffive diffimilar exerti- ons of the retina, mentioned in thi^ fection, which referable in miniature the more violent agitations of the limbs in con vu Hive difeafes, as epilepfy, chorea S. Viti, and opifthotonos; all which difeafes are per- haps, at firfl, the confequence of pain, and have their periods afterwards eftabliihed by habit. VIII. The retina, after having been excited into aclion by ajlimulus fomewhat greater than the laft menti- onedy falls into a fxed fpafawdic affwn, which con- tinuesfor fome days. i. AFTER having looked long at the meridian fun, in making fome of the preceding experiments, till the difks faded into a pale blue, 1 frequently ob- ferved a bright blue fpectrum of the fun on other objects all the next and the fucceeding day, which conftamly occurred when I attended to it, and fre- quently when I did not previoufly attend to it. When I clofed and covered my eyes, this appeared of a dull yellow ; and at other times mixed with the colours of other objects on which it was thrown. It may be imagined, that this part of the retina was become infenfible to white light, and thence a blu- ifh fpectrum became vifible on all luminous objects; but as a yellowifh fpectrum was alfo feen in the clofed and covered eye, there can remain no doubt of this being the fpectrum of the fun. A fimilar appearance was obferved by M. ^pinus, which he acknowledges he could give no account of. (Nov. Com. Petrop. V. 10. p. 2. and 6.) The 614 OCULAR SPECTRA. Stcj. XL 9, 10. The locked jaw, and fotne cataleptic fpafms, are refembled by this phenomenon ; and from hence we may learn the danger to the eye by infpecling very luminous objects too long a time. IX. A quantity of Jlimulus greater tlian the preceding induces a temporary paralyfis of the organ ofvijion. 1. PLACE a circular piece of bright red filk, about half an inch in diameter, on the middle of a fheet of white paper ; lay them on the fioor in a bright funfhine, and fixing your eyes (teadily on the center of the red circle, for three or four minutes, at the diftance of four or fix feet from the object, the red filk will gradually become paler, and finally ceafe to appear red at all. 2. Similar to thefe are many other animal facts ; as purges, opiates, and even poifons, and contagi- ous matter, ceafe to fUrriulate our fyftem, after we have been habituated to their ufe. So fome people fleep undifturbed by a clock, or even by a forge hammer in their neighbourhood : and not only con- tinued irritations, but violent exertions of any kind, are fucceeded by temporary paralyfis. The arm drops down after violent action, and continues for a time ufelefs ; and it is probable, that thofe who have perifhed fuddenly in fwimming, or in fcating on the ice, have owed their deaths to the paralyfis, or extreme fatigue, which fucceeds every violent and continued exertion. X. MISCELLANEOUS REMARKS. THERE were fome circumftances occurred in making thefe experiments, which were liable to alter the refults of them, and which I fhall here mention for SECT. XL. io. OCULAR SPECTRA, ft 5 for the afliftance of others, who may xvifh to repeat them. I, Of dire ft and mverfe fpeflra exlflwg at the Jaws time ; of reciprocal dlrstl fpedra ; of a combination of direft and inverfe fpeftra ; of a fpeflral halo ; rules to predetermine the colours of fpeftra. a. When an area, about fix inches fquare, of bright pink Indian paper, had been viewed on aa area, about a foot fquare, of white writing paper, the internal fpectrum in the clofed eye was green, being the reverfe fpectrum of the pink paper; and the external fpeetrum was pink, being the direct fpectrum of the pink paper. The fame circum- ftance happened when the internal area was white, and external one pink ; that is, the internal fpectrum was pink, and the external one green. All the fame appearances occurred when the { ink paper was laid on a black hat. b. When fix inches fquare of deep violet polifhed paper was viewed oh a foot fquare of white writing paper, the internal fpectrum was yellow, being the reverfe fpectrum of the violet paper, and the exter- nal one was violet, being the direct fpectrum of the violet paper. c. When fix inches fquare of pink paper was viewed on a foot fquare of blue paper, the internal fpectrum was blue, and the external fpectrum was pink ; that is, the internal one was the direct fpec- trum of the external object, and the external one was the direct fpedtrum of the internal object, inflead of their being each the reverfe fpectrum of the objects they belonged to. d. When fix inches fquare of blue paper were viewed on a foot fquare of yellow paper, the inte- rior fpectrum became a brilliant yellow, and the exterior one a brilliant blue. The vivacity of the fpectra 626 OCULAR SPECTRA. SECT. XL. 10. fpectra was owing to their being excited both by the ftimuius of the interior and exterior objects ; fo that the interior yellow fpectrurn was both the reverfe fpectrum of the blue paper, and the direct one of the yellow paper ; and the exterior blue fpectrum was both the reverfe fpectrum of the yellow paper, and the direct one of the blue paper. e. When the internal area was only a fquare half- inch of red paper, laid on a fquare foot of dark violet paper, the internal fpectrum was green, with a reddifh-bluc halo. When the red internal paper was two inches fquare, the internal fpectrum was a deeper green, and the external one redder. When the internal paper was fix inches fquare, the fpec- trum of it became blue, and the fpectrum of the external paper was red. f. When a fquare half-inch of blue paper was laid on a fix-inch fquare of yellow paper, the fpec- trum of the central paper in the clofed eye was yellow, incircled with a blue halo. On looking long on the meridian fun, the difk fades into a pale blue furrounded with a whitifh halo. Thefe circumftances, though they very much perplexed the experiments till they were invefti- gated, admit of a fatisfa&ory explanation ; for while the rays from the bright internal object in exp. a. fall with their full force on the center of the retina, and, by fatiguing that part of it, induce the reverfe fpectrum, many fcattered rays, from the fame in- ternal pink paper, fall on the more external parts of the retina, but not in fuch quantity as to occa- lion much fatigue, and hence induce the direct fpec- trum of the pink colour in thofe parts of the eye. The fame reverfe and direct fpectra occur from the violet paper in exp. b. : and in exp. c. the fcattered rays from the central pink paper produce a direcl fpec- trum of this colour on the external parts of the eye, while the fcattered rays from the external blue paper produce a direct fpectrum of that colour on the cen- tral SECT. XL. io. OCULAR SPECTRA. 627 tral part oftheeye,inftead of thefe parts of the retina falling reciprocally into their reverfe fpectra. In exp. */.the colours being the reverfe of each other, the fcat- tered rays from the exterior object falling on the cen- tral parts of the eye, and there exciting their direct fpectrum, at the fame time that the retina was ex- cited into a reverfe fpectrum by the central object, and this direct and reverfe fpedrum being of fimi- lar colour, the fuperior brilliancy of this fpectrum was produced. In exp. e. the effect of various quan- tities of ftimulus on the retina, from the different refpedtive fizes of the internal and external areas, induced a fpedrum of the internal area in the center of the eye, combined of the reverfe fpectrum of that internal area and the direct one of the external area, in various fhades of colour, from a pale green to a deep blue, with fimilar changes in the fpec- trum of the external area. For the fame reafons, when an internal bright object was frnall, as in exp. f. inftead of the wrhole of the fpectrum of the ex- ternal object being reverfe to the colour of the in- ternal object, only a kind of halo, or radiation of colour, fimilar to that of the internal object, was fpread a little way on the external fpectrum. For this internal blue area being fo fmall, the fcattercd rays from it extended but a little way on the image of the external area of yellow paper, and could therefore produce only a blue halo round the yel- low fpectrum in the center. If any one mould fufpedl that the fcattercd rays from the exterior coloured object do not intermix with the rays from the interior coloured object, and thus affect the central part of the eye, let him look through an opake tube, about two feet in length, and an inch in diameter, at a coloured wall of a room with one eye, and with the other eye naked ; and he will find, that by fhutting out the lateral light, the area of the wall feen through a tube ap- pears as if illuminated by the funfhine, compared with 6a8 OCULAR SPECTRA. SECT. -XL. jo, with the other parts of it ; from whence arifes the advantage of looking through a dark tube at diftant paintings. Hence we may fafely deduce the following rules to deter mine before hand the colours of all fpeclra. j. The direct fpedtnim w'thout any lateral light is an evanefcent repre fen ration of its ohjett in the un- fatigued eye. 2. With fome lateral light it becomes of a colour combined of the dire6t fpetfrnm of the central objeft, and of the circumjacent objects, in proportion to their refpe&ive quantity and brillian- cy. 3. The reverfe fpedrum without lateral light is a reprefentaticn in the fatigued eye of the form of its objects, with fuch a colour as would be pro- duced by all the primary colours, except that of the object. 4. With lateral light the colour is compounded 'of the reverfe fpectrurh of the central object, and the idireft fpe&rurn of the circumjacent objects, in propoition to their refpective quantity and brilliancy. 2. Variation and vivacity of the jpe&ra occafioned by extraneous light. The reverfe fpectrum, as has been before explain- ed, is fimilar to a colour, formed by a combina- tion of all the primary colours, except that with which the e\e lus been fatigued in making the ex- periment : fo the reverfe fpectrum of red is fuch a green as would be produced by a combination of all fhe other prifmatic colours Now it muft be ob- ferved, that this reverfe fpe-flrum of red ia there- fore the direft fpeclrum of a combination of all the other prifmatic colours, except the red; whence, on removing the* eye from a piece of red (ilk to a fheet of white paper, the green fpectrum, which is per- ceived, may either be called the reverfe fpectrum of the SECT. XL. 10. OCULAR SPECTRA. 629 the red filk, or the dired fpeclrum of all the rays from the white paper, except the red ; for in truth it is both. Hence we fee the reafon why it is not eafy to gain a direct fpectrum of any coloured ob- ject in the day -time, where there is much lateral light, except of very bright objects, as of the fetting fun, or by looking through an opake tube ; becaufe the lateral external light falling alfo on the central part of ihe retina, contributes to induce the reverfe fpectrum, which is at the fame time the direct fpec- trum of that lateral light, deducting only the colour of the central object which we have been viewing. And for the fame reafon, it is difficult to gain the reverfe fpectrum, where there is no lateral light to Contribute to its formation. Thus, in looking through an opake tube on a yellow wall, and clofing my eye, without admitting any lateral light, thefpec- tra were all at firft yellow ; but at length changed into blue. And on looking in the fame manner on red paper, I did at length .get a green fpectrum ; but they were all :ii. 7. 8. Gout from inflamed liver, xxxv. 2. 2. xviii. 15. xxiv. 2. & in the ftomach, xxiv. 2. 8. xxv. 17. why it returns after evacuations, xxxii. 4. owing to vinous fpiritonly, xxi. 10. periods of, xxxvi. 3. 6. Grinning in pain, xxxiv. i. 3: Gyration on one foot, xx. 5. and 6. H. Habit defined, ii. u. iv. 7. Haemorrhages, periods of, xxxvi. 3. 1 1. from paralyfis of veins, xxyii. I, and 2. Hair and nails, xxxix. 3. 2. colour of, xxxix. 5. i. Harmony, xxii. 2. Head-achs, xxxv. 2. I. Hearing, xiv. 4. Heat, fenfe of, xiv. 6. xxxii 3. r. produced by the glands, xxxii. 3. external and internal, xxxii. 3. i. atmofphere of heat, xxxii. 3. i. increafes during fleep, xviii. 15. Hemicrania, xxxv. 2. i. Hemicrania from decaying teeth, xxxv. 2. I. Hepatitis, caufe of, xxxv. 2. 3. Hereditary difeafes, xxxix. 7. 6. Hermaphrodite infects, xxxix. 5. Herpes, xxviii. 2. from inflamed kidney, xxxv. 2. 2. Hilarity from diurnal fever, xxxvi. 3. i. Hunger, fenfe of, xiv. 8. Hydrophobia, xxii. 3. 3. Hypochondriacifm, xxxiii. i. i. xxxiv. 2. 3. I. Ideas defined, ii. 7. aie motions of the organs of fenfe, iii, 4. xviii. 5, xviii. 10. i. 6, Ideas INDEX. Ideas analogous to mufcular motions, iii. 5. continue fome time, xx. 6. new ones cannot be invented, iii. 6. I. abftracted ones, iii. 7. 4. inconfiftent trains of, xviii. 1 6. perifh with the organ of fenfe, iii. 4. 4. painful from inflammation of the organ, iii. 5. 5. irritative ones, vii. i. 4. vii. 3. 2. xv. 2. xx. 7. of refemblance, contiguity, caufation, viii. 3. 2. x. 3. 3. refemble the figure and other properties of bodies, xiv. t. 2. received in tribes, xv. i. of the fame fenfe eafier combined, xv. i. i. of reflection, xv. i. 6. ii. 12. Ideal prefence, xv. i . 7. Identity, xv. 3.5. xviii. 13. Iliac paflion, xxv. 15, > Imagination, viii. i. 2. xv. i. 7. xr. 2. 2. of the male forms the fex, xxxix. 6. Immaterial beings, xiv. i. xiv. 2. 4. Imitation, origin of, xii. 3. 3. xxxix. 5. xxii. 3. xvi. 7. Impediment of fpeech, xvii. i. 10. xvii. 2. 10. Infection. See Contagion. Inflammation, xii. 2. 3. xxxiii. 2. 2. great vafcular exertion in, xii. 2. I. Hot from pains from defect of ftimulus, xxxiii. 2. 3. of parts previoufly infenfible, xii. 3. 7. often diflant from its caufe, xxiv. 8. obferves folar days, xxxii. 6. of the eye, xxxiii. 3. i . of the bowels prevented by their continued action in - fleep, xviii. 2. Inoculation with blood, xxxiii. 2. 10. Infane people*, their great ftrength, xii. i. Infanity (fee Madnefs) pleafurable one, xxxiv. 2. 6. Infects, their knowledge, xvi. 1 5. and 1 6. in the heads of calves, xxxix. i . clafs of, xxxix. 4. 8. Inftinctive actions defined, xvi. i . Inteftines, xxv. 3. Intoxication relieves pain, why, xxi. 3. from food after fatigue, xxi. 2. difeafes from it, xxi. 10. See Drunkennefs. Intuitive analogy, xvii. 3. 7. Invention, xv. 3. 3. Irritability increafes during fleep, xviii. !£• Itching, xiv. 9. Jaw-locked, INDEX. J. Jaw-locked, xxxiv. i. 5. Jaundice from paralyfis of the liver, xxx. 2. cured by electricity, xxx. 2. Judgment, xv. 3. K. Knowledge of various animals, xvi. 1 1. L. Lacrymal fack, xvi. 8. xxiv. 2. and 7. Lacleals, paralyfis of, xxviii. See Abforbents. Lady playing on the harpfichord, xvii. 2. diftrefled for her dying bird, xvii. 2. 10. Language, natural, its origin, xvi, 7. and 8. of various paflions defcribed, xvi. 8. artificial, • of various animals, xvi. 9. theory of, xxxix. 8. 3. Lapping of puppies, xvi. 4. Laughter explained, xxxiv. 1.4. from tickling, xvii. 3.5. xxxiv. 1.4. from frivolous ideas, xxxiv. 1.4. xviii. 12. Life, long, art of producing, xxxvii. Light has no momemtum, iii. 3. i. Liquor amnii, xvi. xxxviii. 2. is nutritious, xxxviii. 3. frozen, xxxviii. 3. Liver, paralyfis of, xxx. i . 4. large of geefe, xxx. i. 6. Love, fentimental, its origin, xvi. 6. animal, xiv. 8. xvi. 5. Lunar periods affect difeafes, xxxii. 6. Luft, xiv. 8. xvi. 5. Lymphatics, paralyfis of, xxviii. See Abforbents. M. Mad-dog, bite of, xxii. 3.3. Madnefs, xxxiv. 2. I. xii. 2. i. Magnetifm, xii. i. i. Magnifying objects, new way of, xl. 10. 5. Male animals have teats, xxxix 4. 8. pigeons give milk, xxxix. 4. 8. Man diftinguifhed from brutes, xi. 2. 3. xvi. 17. Material world, xiv. i. xiv. 2. 5. xviii. 7. Matter, penetrability of, xiv. 2. 3, purulent, xxxiii. 2. 4. Meafles, xxxiii. 2. 9. c Membranes* INDEX. Membranes, xxvi. 2. Memory defined, ii. 10. xv. I. 7. xv. 3. Menftruation by lunar periods, xxxii. 6, Mifcarriage from fear, xxxix. 6. 5. Mobility of fibres, xii. i. 7. Momentum of the blood, xxxii. 5. 2. fometimes increafed by venefeftion, xxxii. 5. 4. Monfters, xxxix. 4. 4. and 5. 2. without heads, xxxviii. 3. Moon and fun, their influence, xxxii. 6. Mortification, xxxiii. 3. 3. Motion is either caufe or effect, i. xiv. 2. 2. primary and fecondary, L animal, i. iii. i . propenfity to, xxii. i. animal, continue ibmctirae after their production, xvii. 1.3. defined, a variation of figure, iii. i. xiv. 2. 2. xxxix. 7. Mucus, experiments on, xxvi. i. fecretion of, xxvi. 2. Mules, xxxix. 4. 5. and 6. xxxix. 5. 2. Mule plants, xxxix. 2. Mufcae volitantes, xl. 2. Mufcles conftitute an organ of fenfe, xiv. 7. ii. j. ftimulated by extenfioD, xi. i. xiv. 7. contra® by fpirit of animation, xii. i . I . and 3. Mufic, xvi. 10. xxii. 2. Mufical time, why agreeable, xii. 3. £. N. Naufea, xxv. 6. Nerves and brain, ii,-2. 3. extremities of, form the whole fyflem, xxxvii. 3. are not changed with age, xxxvii. 4, Nervous pains defined, xxxiv. i. I. Number defined, xiv. 2. 2. Nutriment for the embryon, xxxix. 5. 2. Nutrition owing to ftimulus, xxxvii. 3. by animal feleition, xxxvii. 3. when the fibres are elongated, xxxvii. 3. like inflammation, xxxvii. 3. O. Objects long viewed become faint, iii. 3. 2. Ocular fpeclra, xl. Oil externally in diabetes, xxix. 4. Did age from inirritability, xxxvii. Opium is ftimulant, xxxii. 2. 2. promotes abforption after evacuation, xxxiii. 2. 10. in increafing dofes> xii. 3. i. Organs INDEX. Organs of fenfe, ii. 5. and 6. Organs when deftroyed ceafe to produce ideas, iii. 4. 4. Organic particles of Buffon, xxxvii. 3. xxxix. 3, 3. Organ-pipes, xx. 7. Oxygenation of the blood, xxxviii. P. Pain from excefs and defect of motion, 17*5. xii. 5. 3. xxxiv. l» xxxv. 2. i. not felt during exertion, xxxiv. I. 2. from greater contraction of fibres, xii. J. 6. from accumulation of fenforial power, xii. 5. 3. xxiii. 3. l-> from light, prefTure, heat, cauflics, xiv. 9. in epilepfy, xxxv. 2. i. diftant from its caufe, xxiv. 8. from itone in the bladder, xxxv. 2. i. of head and back from defect, xxxii. 3. from a gall-ftone, xxxv. 2. i. xxv. 17. of the ftomach in gout, xxv. 17. of moulder in hepatites, xxxv. 2. 4. produces volition, iv, 6. Palenefs in cold fit, xxxii. 3. 2. Palfies explained, xxxiv. i. 7. Paralytic limbs ftretch from irritation, vii. I. J. patients move their found limb much, xii. 5. i. Paralyfis from great exertion, xii. 4. 6. from lefs exertion, xii. 5. 6. of the lacteals, xxviii. of the liver, xxx. 4. of the right arm, why, xxxiv. I. 7. of the veins, xxvii. 2. Particles of matter will not approach, xii. i . I. Paffions, xi. 2. 2. connate, xvi. I. Pecking of chickens, xvi. 4. Perception defined, ii. 8. xv. 3. i. Periods of agues, how formed, xxxii. 3. 4. of difeafes, xxxvi. of natural actions and of difeafed actions, xxxvi. Perfpiration in fever-fits, xxxii. 9. See Sweat. Petechiz, xxvii. 2. Pigeons fecrete milk in their ftomachs, xxxix. 4. 8. Piles, xxvii. 2. Placenta a pulmonary organ, xxxviii. 2. Pleafure of life, xxxiii. i. xxxix 5. from greater fibrous contractions, xii. I. 6. what kind caufes laughter, xxxiv. i . 4. what kind caufes fleep, xxxiv. I. 4. Pleurify, periods of, xxxvi. 3. 7. caufe of, xxxv. 2. 3. c 2 Prometheus INDEX. Prometheus, ftory of, xxx. 3. Proftration of ftrength in fevers, xii. 4« '• Pupils of the eyes large, xxxi. i . Pulfe quick in fevers with debility, xii. I. 4. xii. 5. 4. xxxii. 2. *. in fevers with ftrength, xxxii. 2. from defect of blood, xxxii. 2. 3. xii. I. 4. weak from emetics, xxv. 17. CL Quack advertifements injurious. Preface. Quadrupeds have no fanguiferous lochia, xxxviii. 2. have nothing fimilar to the yolk of egg, xxxix. I. R. Rhaphania, periods of, xxxvi. 3. 9. Reafon, ix. i. 2. xv. 3. Reafoning, xv. 3. Recollection, ii. 10. ix. i. 2. xv. 2. 3. Relaxation and bracing, xxxii. 3. 2. Repetition, why agreeable, xii. 3. 3. xxii. 2. Refpiration affected by attention, xxxvi. 2. i. Reftleflhefs in fevers, xxxiv. i . 2. Retrograde motions, xii. 5. 5. xxv. 6. xxix. n. of the ftomach, xxv. 6. of the fkin, xxv. 9. of fluids, how. diftinguifhed, xxix. 8. how caufed, xxix n. 5. vegetable motions, xxix. 9. Retina is fibrous, iii. 2. xl. i. is active in vifion, iii. 3. xl. i. excited into fpafmodic motions, xl. 7. is fenfible during fleep, xviii. 5. xix. 8. Reverie, xix. i. xxxiv. 3. cafe of a fleep-walker, xix. 2. * ^ } is an epileptic difeafe, xix. 9. Rhymes in poetry, why agreeable, xxii. 2. K.heumatifm, three kinds of, xxvi. 3, Rocking young children, xxi. 4. Rot in fheep, xxxii. 7. Ruminating animals, xxv. I. S. Saliva produced by mercury, xxiii? by food, xxiii. i. by ideas, xxiii. 2. and 5. by difordered volition, xxiii. 7, Schirrous tumours revive, xii. 2. 2. Screaming in pain, xxxiv. i. 2. Scrophula, its temperament, xxxi. i. xxviii. 2. xxxix. 4. 5. Scurvy, INDEX. Scurvy of the lungs, xxvii. 2. Sea-ficknefs, xx. 4. flopped by attention, xx. 5. Secretion, xxxiii. i. xxxvii. increafed during deep, xviii. 16. Seeds require oxygenation, xxxviii. 2. Senfation defined, ii. 9. v. 2. xxxix. 8. 4. difeafes of, xxxiii. from fibious contractions, iv. 5. xii. i. 6. in an amputated limb, iii. 7. 3. affects the whole fenforium, xi. 2. produces volition, iv. 6. Senfibility increafes during fleep, xviii. 1 5. Senfitive motions, viii. xxxiii. 2. xxxiv. i. fevers of two kinds, xxxiii. i. 2. ideas, xv. 2. 2. Senforium defined, ii. i. Senfes correct one another, xviii. 7. diftinguifhed from appetites, xxxiv. I. I, Senforial power. See Spirit of Animation. great expence of in the vital motions, xxxii. 3. 2. two kinds of exerted in fenfitive fevers, xxxiii. i. 3. powers defined, v. i * motions diftinguifhed from fibrous motions, v. 3. not much accumulated in fleep, xviii. 2. powers, accumulation of, xii. 5.. i. exhauftion of, xiii. 4. i. wafted below natural in hot fits, xxxii. 9. 3. lefs exertion of produces pain, xii. 5. 3. lefs quantity of it, xii. 5. 4. Senfual motions diftinguifhed from mufcular, ii. 7. Sex owing to the imagination of the father, xxxiv. 5; xxxix. 7. 6. xxxix. 6. 3. xxxix. 6. 7. Shingles from inflamed kidney, xxxv. 2. 2. Shoulders broad, xxxi. i. xxxix. 7.6. Shuddering from cold, xxxiv. I., i. and 2. Sight, its accuracy in men, xvi. 6. Skin, fkurf on it, xxvi. i . Sleep fufpends volition, xviii. I. defined, xviii. 21. remote caufes, xviii. 20. fenfation continues in it, xviii. 2,. from food, xxi. i. from rocking, uniform, founds, xxi. 3. from wine and opium, xxi. i. why it invigorates, xii. 5. i. pulfe flower and fuller, xxxii. 2. 2. interrupted, xxvii. 2. from breathing lefs oxygene, xviii. 20. from being whirled on a millltone, zxiii. 20. Sleep INDEX. Sleep from application of cold, xviii. 20. *' •/•*'* ' induced by regular hours, xxxvi. 2. 2; Sleeping animals, xxi. 2. 2. Sleep-walkers. See Reverie, xix. i. Small-pox, xxxiii. 2. 6. xxxiv. 6. 1. eruption firft on the face, why, xxxv. I. i. xxxiii. 2. 10. the blood will not infect, xxxiii. 2.10. obeys lunations, xxxvi. 4. Smell, xiv. 5. xvi* 5. Smiling, origin of, xvi. 8. 4. Solidity, xiv. 2. i. Somnambulation. See Reverie, xix. i. Space, xiv. 2. 2. Spafm, doctrine of, xxxii. 10. Spectra, ocular, xl. miftaken for fpectres, xl. 2. vary from long infpection, iii. 3.5, Spirit of animation. See Senforial Power. of animation caufes fibrous contraction, iv. 2. fi. I. xiv. 2^4. pofTefTes folidity, figure, and other properties of matter, xiv. 2-5- Spirits and angels^ xiv. 2. 4. Stammering explained, xvii. i. 10. xvii. 2. 10. Stimulus defined, ii. 13. iv. 4. xii. 2. I. of various kinds, xi. i. with leflened effect, xii. 3. i. with greater effect, xii. 3. 3. ceafes to produce fenfation, xii. 3. 3. Stomach and inteftines, xxv. inverted by great ftimulus, xxv. 6. its actions decreafed in vomiting, xxxv. i. 3. a blow on it occalions death, xxv. 17. Stools bkck, xxvii. 2. Strangury, xxxv. 2. I. • j Sucking before nativity, xvi. 4. Suckling children, fenfe of, xiv. 8. Suggeftion defined, ii. 10. xv. 2. 4. Sun and Moon, their influence, xxxii. 6. Surprife, xvii. 3. 7. xviii. 17. Sufpicion attends madnefs, xxxiv. 2. 4. Swallowing, act of, xxv. I . xvi. 4. Sweat, cold, xxv. 9. xxix. 6. in hot fit of fever, xxxii. 9. in a morning, why, xviii. 5. Sweaty hands cured by lime, xxix. 4. 9. Swinging and rocking, why agreeable, xxi. 3* Sympathy, xxxv. i. Syncope, xii. i* xxxiv. 7. 6. Tape-worm, INDEX. Tape-worm, xxxix. 2, 3. Tafte, fenfe of, xiv. 5. Tears, fecretion of, xxiv. from grief, xvi. 8. 2. from tender pleafure, xvi 8. 5. from ftimulus of naful duct, xvi. 8. xxiv. 4. by volition, xxiv. 6. Teeth decaying caufe head-achs, xxxv. 2. I. Temperaments, xxxi. Theory of medicine, wanted. Preface. Third, fenfe of, xiv. 8. why in dropfies, xxix. 5. Tickle themfelves, children cannot, xvii. 3^5. Tickling, xiv. 9. Time, xiv. 2. 2! xviii. 12. lapfe of, xv. 3. 6. poetic and mufical, why agreeable, xxii. 2. dramatic, xviii. 12. Tsedium vitae. See Ennui. Tooth-edge, xvi. 10. iii. 4. 3. xii. 3. 3. Touch, fenfe of, xiv. 2. i. liable to vertigo, xxi. 9. * of various animals, xvi. 6. Trains of motions inverted, xii. 5. 5. Transfufion of blood in nervous fever, xxxii. 4. Tranflations of matter, xxix. 7. Typhus, beft quantity of flimulus in, xii. 7. 8. periods of obferve lunar days, xxxii. 6. U. Ulcers, art of healing, xxxiii. 3* 2. of the lungs, why difficult to heal, xxviii. 2. Uniformity in the fine arts, why agreeable, xxii. 2. Urine pale in intoxication, xxi. 6. paucity of in anafarca, why, xxix. 5. its paflage from inteftines to bladder, xxix. 3, copious during fleep, xviii. 15. V. Variation, perpetual, of irritability, xri. 2. I. Vegetable buds are inferior animals, xiii. I. exactly referable their parents, xxxix. pofTefs fenfation and volition, xiii. 2. have aflbciate and retrograde motions, xiii. 4. xxix. 9. their anthers and ftigmas are alive, xiii. 5. Vegetables have organs of fenfe and ideas, xiii. 5. • contend for light and air, xxxix. 4. 8. duplicature of their flowers, xxxix. 4. 4. Veins INDEX. Veins are abforbents, xxvii. I. paralyfis of, xxvii. I. Venereal orgafm of brutes, xxxii. 6. Venxfeclion in nervous pains, xxxii. 5. 4. Verbs of three kinds, xv. 3. 4. Verfes, their meafure, xxii. 2. Vertigo, xx. defined, xx. n. in looking from a tower, xx. I. in a fhip at fea, xx. 4. of all the fenfes, xxi. 9. by intoxication, xxxv. I. 2. Vibratory^notions perceived after failing, xx.5» xx. 10. Vinegar makes the lips pale, xxvii. I. Vis medicatrix of nature, xxxix. 4. 7. Vifion, fenfe of, xiv. 3, Volition defined, v. 2. xxxiv. I. affects the whole fenforium, xi. 2. difeafes of, xxxiv. Voluntarily, x. 2. 4. Voluntary motions, ix. xxxiv. I. ideas, xv. 2. 3. criterion of, xi. 2. 3. xxxiv. I. Vomiting from vertigo, xv. 8. from drunkennefs, xx. 8. xxi. 6. by intervals, xxv. 8. by voluntary efforts, xxv. 6. of two kinds, xxxv. I. 3. in cold fit of fever, xxxii. 9. I. flopped by quickfilver, xxv. 16, weakens the pulfe, xxv. 17. W. Waking, how, xviii. 14. Walking, how learnt, xvi. 3. Warmth in fleep, why, xviii. 15. Weaknefs defined, ?ii. I. 3. xii, 2. I. xxxii. 3. 2. cure of, xii. 7. 8. See Debility. Wit producing laughter, xxxiv. 1.4. World generated, xxxix. 4. 8. Worm-fluke, xxxii. 7. END OF THE FIRST VOLVMS, Hi SIKH