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TREASURY DEPARTMENT
UNITED STATES PUBLIC HEALTH SERVICE
HYGIENIC LABORATORY—BULLETIN No. 119
NOVEMBER, 1919 i B;
lological
erals
DIGEST OF COMMENTS
THE PHARMACOPGIA OF THE
UNITED STATES OF AMERICA
AND ON THE
NATIONAL FORMULARY
FOR THE CALENDAR YEAR
ENDING DECEMBER 31
1916
By
A. G. DUMEZ
WASHINGTON
GOVERNMENT PRINTING OFFICB
1919
SET YO ADTOD,
ADISEMA FO ri
= eet WOCaR
YiAIUR AOE o
sv hala ca eae
pe ee
. 7
nore ty
anives CORTE ‘wae
» > = &
7
i
ORGANIZATION OF HYGIENIC LABORATORY.
RUPERT BLUE, Surgeon General,
United States Public Health Service,
ADVISORY BOARD.
Col. Eugene R. Whitmore, Medical Corps, United States Army; Rear Ad-
miral E. R. Stitt, United States Navy; Dr. John R, Mohler, Chief of United
States Bureau of Animal Industry; and Surg. George W. McCoy, United States
Public Health Service, ex officio...
_ Prof. William H. Welch, Johns Hopkins University, Baltimore, Md.; Prof.
Simon Flexner, Rockefeller Institute for Medical Research, New York; Prof.
Victor C. Vaughan, University of Michigan, Ann Arbor, Mich.; Prof. William
-T. Sedgwick, Massachusetts Institute of Technology, Boston, Mass.; Prof. M. P.
avenel, University of Missouri, Columbia, Mo.
LABORATORY CORPS,
Director.—Surg. George W. McCoy.
Assistant director.—Surg. A. M. Stimson,
Senior pharmacist.—C. O. Sterns, Ph. G.
_ Junior pharmacist—Claude C. Cannon, Ph. OC,
: Artist—Leonard H. Wilder. .
Librarian.—Murray G. Motter, A.M. 5 M.D:
DIVISION OF PATHOLOGY AND BACTERIOLOGY,
In charge of division—Surg. George W. McCoy. Assistants.—Surgs. B. J.
Lloyd, Edward Francis, Arthur M. Stimson, C. W. Chapin; Passed Asst. Surgs.
HH. E. Hasseltine, James P. Leake, Mather H. Neill, Gleason C. Lake.
Bacteriologist.—T. W. Kemmerer, M. D.
Sanitary Bacteriolgists—Hugh B. Corbitt, B. S., Ida A. Bengtson, M. §., Alice
C. Evans, M. S8., Clara E. Taft, B. S., Ella M. A. Enlows, M. S.
Technical Assistant.—Walter D. Cannon, LL. B., A. M., M. D.
Bacteriologic Technician.—William Lindgren,
DIVISION OF ZOOLOGY,
Chief of Division—Ch. Wardell Stiles, Ph. D.
Laboratory Aids.—Mary L. Brown, B. E., Margaret George, A. B., Margaret
Wood, B. 8., Gordon Thomson, A. B.
DIVISION OF PHARMACOLOGY,
Chief of Diwision.—Carl Voegtlin, Ph. D.
Technical Assistants.—Atherton Seideil, Ph. D., A. G. DuMez, Ph. D., George
B. Roth, M. D.
Pharmacologist.—A. C. Kolls, M. S., M. D.
Physiologist.—Alfred B. Livingston, M. 8., Ph. D.
Pathologic Physiologist—Charles W. Hooper, M. D.
(3)
4
Chemist.—James M. Johnson, Ph. D.
Assistant Chemist.—H. D. Smith, B. S.
Junior Chemist—John W. Thompson, B. S.
Scientific Assistants.—K. Dorothy Wright, A. B., Mabel A. Connell, B. 8S.
DIVISION OF CHEMISTRY.
Chief of Division.—Vacant.
Chemist.—Elias Elvove, M. S., Pharm. D., in charge of the division ad interim.
Technical Assistant—Hyman L. Shoub, B. S.
Assistant Chemist.—Elbridge J. Casselman, B. S.
Assistants in Chemistry.—Charles G. Remsburg, B. S., Oliver H. Schunk, B. 8S.
SPECIAL DETAIL.
Surgs. Hugh S. Cumming, Taliaferro Clark, Carroll Fox; Passed Asst. Surg.
7, 4. Carmelia; Asst. Surgs. Charles Armstrong, C. E. Gibbs.
Scientific Assistant Samuel Saunders, M. D. :
Special Experts Julius Stieglitz, Ph. D., Russell L. Cecil, M. D.
Bacteriologist W. A. Perlsweig, B. S.
Organic Chemist Liston A. Steffin, B. S.
*
i Bn
pai w el N@ db a bill
2
ee re, ee eae ee ee eee eee
TABLE OF CONTENTS.
1 ist of literature reviewed:
Pema previa cons —JOUrnals 9. = ee ee ee ee
2. Title abbreviations—Pharmacopeias and nonoflicial standards____
. General comments:
1. Legal statis and development—
Pe neetOud Ano Glule IA WS ooo aa woe ee cee ee oS re
PECTS Se sOle POLSON See oa noe ae ee eS
Bm Snevand: use of Narcotic rugs ee eS ee
4. Sale and use of household remedies_____-__________________
SEOUL SO CCLION WOR. een 2 tne id SE ON ese
6. The Pharmacopeceia as a legal standard_____._________-___-_
7. General principles followed in revision_______ AA FOUN. - Oe,
Pera CatiOm and = CONntOl ee Pe ee
othe physician ‘and: the Pharmacopmia_----_ 22 a
SL USAT CB: OE GPE ECCI ia pal a a aa a Ae
ia Natre and progress Of revision. U2) oe ee
2. Scope—
. Nature and content of the Pharmacopeia______-__________-_
Peboe Ee narmacopmeia.as, a textbook 22 ———* 2s ee
MIE Niateria: MECCA = 2 2 So as ee es eae
2 PEPE CASE CGUG Tey Weg ac al Re at AS Lh gree lh a Aaa A ie es ee
DH
PAD ap w
y
i=]
oz
|=
O
cf
2
|
aR een ee Se et ee eee eee
MES re G ENON SUES ee. 2 a as ee ee
DY EYECCLRS) ENG ACTRESS et eR eT
Mea aiitoOnscand -Celenons-— 222 eo ee ee ESS
PemLateya SHUM SPeene il asa nS Se ear se
PT OTIC a VEL GS 2 ees ee ee OE eo eee aes
8. Nonpharmacopeial standards—
ee eNO SUL ON Tua TY es Ss ee
POPER ECCT) OO Katee ree ee SS ee ee
Boenew. and nonofieial remedies. __—____ = = --= == =.= 2-2 eS
SSL GS a ee _ a Rl Reena ee era a ein eS See
SW MERON CMI Ogee ofa). Se oe on ee eee ye eee
tenis AuOnbraAGe-MArK S222 oe eee ee ee
CCUCGYSTYO) 1 OCs Hi 0 p eee re ae A ERED RENT Bs nic RE Sete Lo at Dine ee ae
LEO 15 2 1 ea a SN se SRD ep a a
i. LiGIneiE Loy pdit lie: a ee lore ee eee
USUI SS ek a eT aS ee ee eee
SrovHopleln hy 22 a2 5225 eee ee, ae PR tse
EITM O SUE Cl icV SLC CHOSE nse a
Rioig71enl methoos and: Lestsss— 2
PerAniriscntics, And .disintectanits_22 22-2 oe i
(5)
pe
et S&S ©
I. General comments—Continued.
et Analy ticad data: 535. Gees eee Oe eee
1. Adulterdtions 2: --. 22) ==. =.) eee
2. Reagents and. test solutious=== > eee eee
3. Indicators__-________ -_=__= = eee
4, Physical. constants______2_-_ 22S
Specifie gravity_.__.____> __- eee
Solubilities__....- __- "eee
Melting point determinations....— _=s_. = eee
Boiling point determinations. _- ==) =) SS =
Thermometry--2_--_--—_ -_ = ee
Polarization and refraction Ee
5. Chemical constants__-.-.___._ _-— eee
Acid. number__.__ 2) 3 a eee
Ester number 2s2:))—— = ee EEE eee
Iodine absorption values... =e EE eee
Saponification. value. 224. EEE
6. Color statidards and. colors: 22- == = Eee
7. Analytical methods and resultS+_-:_.-)_ Eee
8 Dests2.22-2: so = See Se eee 2 ;
Halogens.-.---=-=-=-===._—. = ee eee
Sulphur and sulphates... EEE
Phosphorus and phosphates. = —-..___-_ eee
Nitrogen, nitrates,,and nitrites________.___ eae
Carbon and carbonates... = Eee
Alkali compoundgSs.....__ _- =. Eee
Alkaline earth compounds__________. eee
Antimony: and arsenic__.______ eee eee
Metals____.._._______-> ee eee
Organic compoundSs____- =~. Eee eee
Sugars.” eee
9. Clinical .tests_...-_.__..___- eee
Urine. 2° o eee eee
Acidity ~._._.__- eee
Acet0ne_..--__.- = eee
Ajbumin ~__.=_-> ee eee
AMMOnia—.—- 22-2. ee eee
Bile. 22 = eee =
Blood... -_ 2 eS eee
Chlorides _____. =...
Indican_ 2 a eee
Sugar__...iL._ =. ee LE
Urea... ne ee
Uric acid. 8
Cammidge reaction-___-2-____ eee
Weces__.__ 2 ee
Gastric contents__...._.______ > eee
Sputum.____
Blood_..._ ea ee
Stains .... 2
Culture media__-
5. Apparatus__-
6.
Filters
. General comments—Continued. Page.
2 SEE ota Woes ee a ie A ee es a ee 102
Peenitivarion Of medicinal plants 2-22) 2 106
PGRN DETR 81 ONT FCS RSI a Te ee ee 108
PeERONE IEC maeLCrININaA TONS. = nae ee ee ee | 109
co ASIN GAei eee nil o i ta) ce Ss Oa Se ee 110
CHIGGS GIGS. Ses So ee neeee er Soe eee oe eee 110
OU TERUTG ENS aS 2 ee renee ee nee Ty SET eee ee eee 111
PeMscelaneous pliant constituents 2. oe 112
rSMMEDLIE CES Rk soe ey Cog ee ee 113
fmeervruolorical Standardization... 115
Pree nLICd! i preparauions.—- == =2-26_ Fe 115
OTe leet Olinty a saeesrres | le Coe 8 ee ee 116
PINT CON NBEShROn OL 472 = te eer ve syed A yor 116
2 ATURE SIN Aha) ae Se a eee ee es eee | fren a ly ¢
PEE SOPUECIMET UR ee oe ee ea 117
UCRRRE ATES fost Seem erent ee pe ce Se 118
OP LSE UE TRG TES RIN is 2a eee A Sas SS CRIS ea A a 118
MME TATALT VENUE) Lye oo oe i es a a a Sek ee 119
PRETENCE OMS se oe ee ak SS Oe te Sd ed 120
ee ASIEE AGS7 Fel © Ee eee est eh ee ek 120
PEN SOT ACI SUCARION— ot 121
fe, SUSY BOP EIS pay 5 ee ae a a at SI A ce a PAL
a See Seemann tS eet eo ee 122
Soriipeessed. tabletss fe i. sss Se ee ee ee eee 122
mere nods: OL Administration <2 2-2) ah ot ae 122
II. International standards: _
1. The evolution of uniformity in pharmacopeceial standards and for
SMI PCAIRCHIN 2 oe a a 123
1. Adoption of Brussels Conference Protocol_______.__________ 123
Sh EDT ETD) LE ew OEIC 0,02) BIG ee 123
To LEST AS i Se ee ees Se eke ae ee eee ae eee 12S
2 DAD RA ee SO ae ae ed eee | Se ee 124
Sop LER Ties sep 8 er lg a a eg ne ee 124
TST ee ap el te eR a 124
SU STi cas Sat ae CEE A SU ees SS 2 Re oe «Teta Be ee 124
Pelee enimenEson OHicialiarticles. =2=- 22. 2-65.22 Se he 125
PREFACE.
This bulletin is the twelfth in the series of Hygienic Laboratory
publications, known as the Digest of Comments on the Pharmacopcia
of the United States of America and the National Formulary. Like
the preceding bulletins of this series, it is a comprehensive index of
all available literature which may be of interest or of value in con-
nection with the revision of the two standard works mentioned in the *
title. The marked reduction in the number of pages from that of
preceding numbers is not the result of an attempt on the part of
the compiler to narrow the scope of the work, but is due to a dimi-
nution in the number of articles pertaining to pharmaceutical re-
search published during the year 1916, and to the fact that a number
of the foreign periodicals have not been received in this country of
late. In fact, the publication of some of these journals has been
suspended for the period of the war.
In this, as in the preceding numbers of the bulletin, all of the
available literature has been gone over carefully and the abstracts
have been made as concise as possible without detracting from their
value as working references. In. those cases where the articles
were of such a nature that they could not be abstracted with ad-
vantage, merely the titles have been given.
No attempt has been made to differentiate between the references
of greater or lesser importance. Comprehensive discussions or re-
ports are given comparatively little space, the intent being to call
attention to the character and scope of the original paper rather
than to make a complete record of its content. Some idea of the
importance of an article may, however, be formed from its length,
as indicated by the page reference.
In citing references no attempt has been made to record all of
the periodicals in which a given paper may have appeared. As a
rule, the reference most easily accessible to the American pharmacist
has been given preference, even in those cases where the original
paper did not appear in the publication recorded. With respect to
the papers presented at the annual meetings of the British Phar-
maceutical Conference, references are only given to the Pharma-
ceutical Journal and the Yearbook, it being understood that wher-
ever these two references appear conjointly the article can also be
found in the British and Colonial Druggist and the Chemist and
Druggist.
(9)
10
As a result of the appearance of the revised editions of the United
States Pharmacopeia (U. S. P. TX) and the National Formulary
(N. F.IV), which became official on September 1,1916, the literature —
of the latter part of the year was of special importance, as it con-
tained many interesting reviews of these standards. General refer-
ences to articles of this nature are recorded under the subdivision
devoted to comments on the nature and content of the Pharma-
copeeia, whereas the specific comments contained in these articles
are recorded under the respective items to which they refer.
In view of the fact that the new editions of the United States
_Pharmarcopeia and the National Formulary contain chapters on
sterilization and that the former also contains chapters on diagnos-
tical reagents and culture media, articles dealing with these subjects
have been abstracted in greater number than in previous issues of
the bulletin. Even under these conditions, however, the abstracts
which have been included refer only to the more important articles
on these subjects as a complete review of the literature was im-
possible in the time allotted to this work.
In addition to comments which have a direct bearing on the two
legally recognized drug standards of the United States, an effort has
been made to include abstracts of articles which are of indirect in-
terest in this connection. This bulletin, therefore, includes a num-
ber of abstracts of articles dealing with the food and drug laws,
antinarcotic laws, poison laws, drug inspection work, sera and vac-
cines, drug plant cultivation, foreign pharmacopeias, works on
standards, etc. In view of the limited amount of time at the dis-
posal of the compiler, no attempt has been made to record in a com-
prehensive way all that has been printed on these subjects during the
year, the object having been to select such material as would bring
out the general trend of comment.
Reference to articles dealing with the quality of medicinal pro-
ducts are not as numerous as in previous publications of this series
as the anaytical reports of many of the foreign pharmaceutical manu-
facturing houses have not been issued since the beginning of the war.
The information of this nature which has been available in this
country has been recorded under the heading “ Drug Inspection
Work,” or in tabular form under each specific item.
The continuance of the war in Europe has brought home to the
American pharmacist the desirability of becoming independent of
Europe in the matter of securing his supplies of drugs and medicines.
As a consequence, the cultivation of medicinal plants in the United
States has received added attention in our schools of pharmacy as
well as in the commercial world. Abstracts of articles pertaining to
the cultivation and collection of drugs have therefore been given
special consideration in the preparation of this bulletin.
1
The war in Europe has not only stimulated an interest in the pro-
duction of drugs, but has brought to our notice in a striking manner
the desirability of controlling their use for illegitimate purposes.
Especially is this true in the case of the improper use of opium, its
alkaloids, and cocaine. In fact, most of the European countries en-
_ gaged in the present struggle have found it necessary to pass
stringent laws prohibiting the sale of these drugs except on the
order of a physician. Abstracts of articles showing the prevailing
conditions and the action taken in these countries are included under
the heading “ Sale and use of narcotics.”
An added interest in the public health feature of pharmacopeial
work has also resulted from the struggle which is at present being
waged in Europe. Never before has the public, as well as the phy-
sician and surgeon, deyoted so much attention to prophylactic
measures and with such satisfactory results as at the present time.
References to articles which have a bearing in this connection have
been included under the headings: “ Serums and vaccines,” “ anti-
septics and disinfectants,” “arsenic (nonofficial compounds),” ete.
As in previous bulletins of this series, comments on foreign phar-
macopeeias have been included whenever they have been available.
In greater part, these have been recorded under the respective phar-
macopeeias, but, where they apply to specific items, they have been
placed under the comments on oficial articles.
In conclusion, the compiler desires to express the appreciation of
the bureau to the publishers and editors of journals and periodicals
furnished in exchange; to the secretaries of state and national phar-
-maceutical organizations for copies of their annual proceedings; to
John Uri Lloyd, of Cincinnati, for copies of the eclectic medical
journals; to the editor of Chemical Abstracts for several foreign pub-
lications; and to the officers of the library of the Department of
Agriculture, the library of the Office of the Surgeon General of the
Army, Washington, and the Library of Congress for the use of re-
ports and periodicals not on file in this laboratory.
A. G. D.
Division or PHARMACOLOGY,
Hyerentc Laporarory,
February 4, 1919.
LIST OF THE LITERATURE REVIEWED.
1. TITLE ABBREVIATIONS—JOURNALS.
4 Am Druggist—American Druggist and Pharmaceutical Record, N. Y., 1916,
i v. G4.
Aim. Food J—American Food Journal (The), Chicago, Ill, 1916, v. 11.
Am. J. Clin. Med.—American Journal of Clinical Medicine, 1916, v. 23.
Am. J. M. Se—American Journal of the Medical Sciences, Philadelphia, 1916,
¥. 152. g
Am. J. Pharm.—aAmerican Journal of Pharmacy, Philadelphia, 1916, v. 88.
Am. J. Physiol—American Journal of Physiology, Boston, 1916, v. 40 and 41.
Am. J. Public Health—American Journal of Public Health, 1916, v. 6.
Am. J. Se.—American Journal of Science, New Haven, 1916, v. 41 and 42.
Am. J. Trop. Dis——American Journal of Tropical Diseases and Preventive Medi-
cine, New Orleans, 1916, v. 3, Nos. 6-11.
Am. Med.—American Medicine, 1916, vy. 22.
Am. Perf.—The American Perfumer and Essential Oil Review, N. Y., 1916, v. 10,
Nos. 11-12; v. 11, Nos. 1-10..-
Anales soc. espanola fis. quim.—Anales de la sociedad espafiola de fisica y
quimica, Madrid, 1915, v. 13.
Analyst (The), London, 1916, v. 41.
Anu, Chem.—Justus Liebig’s Annalen der Chemie, Leipzig, February, 1916.
Ann, chim. analyt.—Annales de chimie analytique, Paris, 1916, v. 21.
Ann. chim. applicata.—Annali ‘di chimica applicata, Roma, 1916, v. 5.
Ann. Falsif—Annales des Falsifications, 1916, v. 9.
Apothecary (The), Boston, 1916, v. 13.
Apoth.-Ztg.—Apotheker-Zeitung, Berlin, 1916, v. 31, Nos. 1-22.
_ Arch. Chem. Mikros.—Archiv fiir Chemie und Mikroskopie, Wien, 1916, v. 9,
Nos. 1 and 2.
Arch, exper. Path. u. Pharmako].—Archiv. fiir experimentelle Pathologie und
Pharmakologie, 1915, v. T9 and 80.
Arch. farmacol. sper.—Archivio di farmacologia sperimentale e Scienze affini,
Sienna, 1916, v. 21 and 22.
Arch. Int. Med.—Archives (The) of Internal Medicine, Chicago, 1916, v. 18.
Archiv Pharm. Chem.—Archiv for Pharmaci og Chemi, Copenhagen, 1916, y. 23.
Arkiv Kem. Min. och Geol.—Arkiv for Kemi, Mineralogi och Geologi, Stockholm,
1916, v. 6, No. 1.
Atti accad. Lincei.—Atti della reale accademie dei Lincei, 1916, v. 25.
Ber. deutsch. chem. Gesellsch.—Berichte der deutschen chemischen Gesell-
schaft, Berlin, 1916, v. 49.
Biochem. J.—Biochemical Journal, Liverpool, 1916, v. 10.
Biochem. Ztschr.—Biochemische Zeitschrift, Berlin, 1916, v. 76 and 77.
Boll. chim.-farm.—Bolletino Chimico-Farmaceutico, Milan, 1916, v. 55. ‘
Boston M. & 8. J— Boston Medical and Surgical Journal, 1916, v. 174 and 175.
-Bot. Gaz.—Botanical Gazette, Chicago, 1916, v. 61.
Brit. & Col. Pharm.—British and Colonial Pharmacist, London, 1916, v. 69, No. 4.
Brit. Food J.—British Food Journal, London, 1916, v. 18.
Brit. M. J— British Medical Journal, London, 1916, v. 1 and 2.
(13)
14
Bull. Arizona Bd. Health.—Bulletin of the Arizona State Board of Health, 1916,
ana
Bull. Assoc. Gén. Syn. Pharm. France.—Bulletin de l’Association Générale =
Syndicats Pharmaceutiques de France, 1916, v. 19.
Bull. Bur. Stand.—Bulletins of the Bureau of Standards, U. S. Department of
Commerce, 1916, v. 13.
Bull. California Bd. Health—Monthly Bulletin, California State Board of —
Health, 1916.
Bull. Colorado Bd. Health—Annual Bulletin Colorado State Board of Health,
1916.
Bull. Connecticut Bd. Health—Monthly Bulletin Connecticut State Board of
Health, 1916, v. 30.
Bull. Florida Bd. Health—Bulletin of the Florida State Board of Health,
Jacksonville, 1916, v. 11.
Bull. Georgia Dept. Agric.——Bulletin, Georgia Department of Agriculture, 1916,
vy. 3, Nos. 1 and 2
Bull. Hyg. Lab.—Bulletins, Hygienic Laboratory, U. S. Public Health Sery-
ice, 1916, Nos. 101 and 102.
Bull. Illinois Bd. Health—Bulletin of the Illinois State Board of Health,
Springfield, 1916, v. 2.
Bull. Indiana Bd. Health.—Bulletin, Indiana State Board of Health, 1916 y. 19.
Bull. Iowa Bd. Health.—Bulletin, Iowa State Board of Health, Des Moines,
1916.
Bull. Kansas Bd. Health.—Bulletin, Kansas State Board of Health, 1916 v. 12,
Bull. Kentucky Bd. Health—Bulletin of the State Board of Health of Ken-
tucky, 1916, v. 6 and 7.
Bull. Lab. Inl. Rev. Dept. Canada.—Bulletins of the Laboratory of the Inland
tevenue Department, Ottawa, Canada, 1916.
Bull. Louisiana Bd. Aare —Quarterly Bulletin. of the Louisiana State Board
of Health, 1916,
Bull. Maine Bd. eG eee of the State Board of Health of Maine,
Augusta, 1916, v. 4
Bull. Massachusetts Bd. Health.—Bulletin, Massachusetts State Board of
Health, 1916, v. 3
Bull. Michigan Bd. Health.—Public Health published by the Michigan State
Board of Health, Lansing, 1916.
Bull. Michigan D. & F. Dept.—Bulletin Michigan Dairy and Food Depart-
ment, 1916, Nos. 244-255.
Bull. Mississippi Bd. Health.—Health Bulletin of the Mississippi State Board
of Health, Jackson, 1916, v. 6.
Bull. Missouri Bd. Health—Quarterly Bulletin of the Missouri State Board
of Health, Jefferson City, 1916, v. 6.
Bull. Montana Bd. Health.—Bulletin (special) of the Montana State Board
of Health, Helena, 1916.
Bull. Montana Dept. Pub. Health—Bulletin of the Department of Public
Health of the State of Montana, Helena, 1916, vy. 9.
Bull. New Hampshire Bd. Health—Quarterly Bulletin of the State Board of
Health of the State of New Hampshire, 1916, v. 4, Nos. 5, 6, 7 and 8.
Bull. New Jersey Agric. Exper. Sta.—Bulletin of the New Jersey Agricultural
Station, New Brunswick, 1916, Bull. Nos. 293, 294, 295, 297 and 303.
Bull. New Jersey Dept. Health—Public Health News Bulletin, Department
of Health of the State of New Jersey, 1916, v. 1 and 2.
Bull. New York Agric, Exper. Sta.—Bulletin of the New York Agricultural
Experiment Station, Geneva, 1916, Bull. No. 416, 419, 420, 424 and 425.
: Bull. New York Dept. Health—Bulletin, New York State Department of
Health, 1916, v. 11.
- Bull. New York City Dept. Health.—Bulletin, New York City Department
of Health, 1916, v. 5.
Bull. North Carolina Bd. Health.—Bulletin, North Carolina State Board of
Health,. 1916, v. 31.
Bull. North Dakota Bd. Health—Bulletin, North Dakota State Board of
Health, 1916, v. 9.
- Bull. North Dakota Exper. Sta. F. Dept.—Bulletin (Special) of the Food
Department of the North Dakota Agricultural Experiment Station, 1916, v. 4.
Bull. Ohio Bd. Health.—Bulletin, Ohio State Board of Health, 1916, v. 7.
Bull. Pharm.—Bulletin of Pharmacy, Detroit, 1916, v. 30.
Bull. Rhode Island Bd. Health.—Bulletin, Rhode Island State Board of
Health, 1916, v. 2.
Bull. soc. chim. France—Bulletin de la société chimique de France, 1916,
v. 19 and 20.
Bull se. pharmacol.—Bulletin des sciences pharmacologiques, Paris, 1916, v. 23.
Bull. South Dakota F. & D. Dept.—Bulletin of the South Dakota Food and
Drug Department, 1916, v. 3 and 4.
Bull. U. S. Dept. Agric.—Bulletins of the U. 8. Department of Agriculture,
1916.
Bull. Vermont Bd. Health—Bulletin, Vermont State Board of Health, 1916,
v. 16, Nos. 3 and 4; v. 17, Nos. 1 and 2.
Bull. West Virginia Bd. Health.—Bulletin, West Virginia Public Health
Council, 1916, v. 3.
Canadian Pharm. J.—Canadian Pharmaceutical Journal, Toronto, 1916, vy.
49 and 50.
Carolina J. Pharm.—Carolina Journal of Pharmacy, Chapel Hill, N. C., 1916,
Vx 2, INO. a
-Centralb. f. Bakteriol—Centralblatt fiir Bakteriologie, Parasitenkunde und
Infectsionskrankheiten, Jena, 1916, v. 77.
Chem. Analyst.—Chemist-Analyst (The), Phillipsburg, N. J., 1916, Nos. 17-19.
Chem. & Drug.—Chemist and Druggist, London, 1916, v. 88.
Chem. & Drug. Australas——Chemist and Druggist of Australasia, Sydney and
Melbourne, 1916, vy. 31.
Chem, Eng.—Chemical Engineer, Chicago, 1916, v, 23 and 24.
Chem. News.—Chemical News, London, 1916, v. 114.
Chem. Weekblad.—Chemisch Weekblad, Amsterdam, 1916, y. 13.
Chem. Zentralbl.—Chemisches Zentralblatt, Berlin, 1916, v. 87.
Chem.-Ztg.— Chemiker-Zeitung, Cothen, 1916, v. 40.
Cire. Bur. Stand.—Circulars of the Bureau of Standards, U. 8. Department of
Commerce, 1916.
-- Cleveland M. J.—Cleveland Medical Journal, 1916, v. 15.
Colorado Med.—Colorado Medicine, Denver, 1916, v. 13.
Com. Rep.—Commerce Reports, Daily Consular and Trade Reports issued by
the Bureau of Foreign and Domestic Commerce of the United States Depart-
ment of Commerce, 1916.
Compt. rend. acad. sc.—Comptes rendus hebdomadaires de séances de l’Acedemie
des sciences, Paris, 1916, v. 162 and 163.
Compt. rend. soc. biol—Comptes rendus des seances de la Société de Biologie,
Paris, 1916, v. 79.
Critic and Guide, New York, 1916, v. 19. :
Cc. U. C. P. Alumni J.—Columbia University College of Pharmacy, Alumni
Journal, New York, 1916, v. 23.
16
Dental Cosmos, Philadelphia, 1916, v. 58.
Dental Digest (The), New York, 1916, v. 22. »
ss -A. Apoth.-Ztg.—Deutsch-Amerikanische Apotheker-Zeitung, New York, 1916,
TOU ,
meee: med. Wehnschr.—Deutsche medizinische Wochenschrift, Berlin, 1916,
v. 42.
Drug. Cire.—Druggists Circular, New York, 1916, v. 60.
Drug Topics, New York, 1916, v. 31.
Eclectic M. J.—Eclectic Medical Journal, Cincinnati, 1916, v. 76.
Ellingwood’s Therap.—EHllingwood’s Therapeutist, Boston, 1916, v. 10.
Exper. Sta. Record.—Experiment Station Record, U. S. Department of Agricul-
ture, 1916, v. 34 and 35.
Farm. Espafii—La Farmacia Espanola, Madrid, 1916, v. 48.
Gaz. Chim. Ital—Gazzetta chimica Italiana, Roma, 1916, v. 46.
Hahnemann. Month.—Hahnemannian Monthly, Philadelphia, 1916, v. 51.
J. Agric. Research.—Journal of Agricultural Research, 1916, v. 5, 6, and 7.
J. Am. Chem, Soc.—Journal of the American Chemical Society, 1916, v. 38.
J. Am. Inst. Homcep.—Journal of the American Institute of Homeopathy,
Chicago, 1916, v. 8 and 9.
J. Am. M. Assoc.—Journal of the American Medical Association, 1916, vy. 66
and 67.
J. Am. Pharm. Assoc.—Journal of the American Pharmaceutical Association,
Philadelphia, 1916, v. 5.
J. Am. Vet. Med. Assoe.—Journal of the American Veterinary Medical Associa-
tion, Ithaca, 1916, v. 48 and 49.
J. Assoe. Off. Agric. Chem.—Journal of the Association of Official Agricultural
Chemists, Baltimore, 1916, v. 1, No. 4.
J. Biol. Chem.—Journal of Biological Chemistry, New York, 1916, v. 24-27.
J. Chem. Soc. Lond.—Journal of the Chemical Society, London, 1916, v. 109-110.
J. chim. phys.—Journal de chimie physique, Genéve et Paris, 1916, v. 14.
J. Exper. M.—Journal of Experimental Medicine, New York, 1916, v. 23 and 24.
J Franklin Institute—Journal (The) of the Franklin Institute, Philadelphia,
1916, v. 181 and 182.
J 4. Hosp. Bull—Johns (The) Hopkins Hospital Bulletin, Baltimore, 1916,
27.
J. Hyg—Journal (The) of Hygiene, Cambridge, 1916, v. 15.
J. Immunol.—Journal of Immunology, Baltimore, 1916, v. 2.
J. Ind. & Eng. Chem.—Journal (The) of Industrial and Engineering Chemistry,
Easton, 1916, v. 8.
J. infec. Dis.—Journal (The) of Infectious Diseases, Chicago, 1916, v. 18 and 19.
J. Iowa State Med. Soe.—Journal of the Iowa State Medical Society, 1916, v. 6.
J. Lab. & Clin. Med.—Journal (The) of Laboratory and Clinical Medicine, St.
Louis, 1915-16, v. 1.
Journal-Lancet, The Journal of the Minnesota State Medical Association and
Official Organ of the North Dakota and South Dakota State Medical Asso-
ciations, 1916, v. 36.
J. Linnean Soc. Bot.—Journal of the Linnean Society, Botany, 1915, vy. 43.
J. Med. Research.—Journal of Medical Research, Boston, 1916, v. 33 and 34.
J. Path. and Bact.—Journal (The) of Pathology and Bacteriology, Cambridge
University, 1916, v. 20.
J. pharm. et chim.—Journal de pharmacie et de chimie, Paris, 1916, v. 12, 18,
und 14, ;
J. Pharmacol, and Exper. Therap.—Journal of Pharmacology and Expert-
mental Therapeutics, Baltimore, 1916, v. 8 and 9.
1
17
3 Physiol.—Journal (The) of Physiology, 1916, v. 50.
J. Phys. Chem.—Journal (The) of Physical Chemistry, Ithaca, 1916, v. 20.
J. Proe. Roy. Soc. New South Wales.—Journal and Proceedings of the Royal
Society of New South Wales, 1916, v. 50.
J. Roy. Micros. Soc.—Journal of the Royal Microscopial Society, 1916.
J. Roy. Soc. Arts.—Journal of the Royal Society of Arts, London, 1916, v. 64,
J. Soc. Chem. Ind.—Journal of the Society of Chemical Industry, 1916, v. 35.
J. Trop. Med. & Hyg.—Journal (The) of Tropical Medicine and Hygiene, Lon-
don, 1916, v. 19.
J. Washington Acad. Se—Journal of the Washington Academy of Sciences,
1916, v. 6.
_ Kolloid-Ztsechr.—Kolloid-Zeitschrift, Dresden and Leipzig, 1916, v. 19,
Lancet (The), London, 1916, v. 190 and 191.
Lilly Sci. Bull.—Lilly (The) Scientific Bulletin, 1916, No. 7.
Med. Council—Medical (The) Gouncil, Philadelphia, 1916, vy. 21,
Med. Rec.—Medical Record, New York, 1916, v. 89 and 90.
Merek’s Rep.—Merck’s Report, New York, 1916, v. 25.
Meyer Bros. Drug.——Meyer Brothers Druggist, St. Louis, 1916, v. 87.
Midl. Drug.—Midland Druggist and Pharmaceutical Review, Columbus, 1916,
v. 50.
Montreal Pharm. J.—Montreal Pharmaceutical Journal, 1916, v. 27.
Mulford’s Vet. Bull—Mulford’s Veterinary Bulletin, Philadelphia, 1916, vy. 7
and 8.
N. A. R. D. J—N. A. R. D. Journal, The Official Organ of the National Associa-
tion of Retail Druggists, Chicago, 1916, v 21, 22, and 23.
Nat. Druggist—National (The) Druggist, St. Louis, 1916, v. 46.
National Drug Clerk (The), Chicago, 1916, v. 4.
Nat. Eclect. M. Assoc. Quart.—The National Eclectic Medical Association Quar-
terly, Cincinnati, 1916, v. 7, No. 3 and 4; v. 8, No. 1 and 2.
Nature, London, 1916, v. 96, 97, and 98.
New Idea (The), Detroit, 1916, v. 38.
New York M. J.—New York Medical Journal, 1916, v. 103-104.
Norges Apotek. Tidsskr.—Norges Apotekerforenings Tidsskrift, Kristiania,
1916, v.24.
Northwestern Druggist, (The), Minneapolis, 1916, v. 17.
Oil, Paint & Drug Rep.—Oil, Paint, and Drug Reporter, New York, 1916,
v. 90.
Pacific Pharm.—Pacific (The) Pharmacist, San Francisco, 1916, v. 9 and 10.
Pennsylvania Med. J.—Pennsylvania Medical Journal, Athens, 1916, v. 19
and 20.
Perf. & Ess, Oil Rec.—Perfumery and Essential Oil Record, London, 1916, v. 7.
Pharm. Era.—Pharmaceutical (The) Era, New York, 1916, v. 49.
Pharm. J.—Pharmaceutical (The) Journal, London, 1916, v. 96 and 97.
Pharm. Post—Pharmazeutische Post, Vienna, 1916, v. 49, Nos. 1-20.
Pharm. Weekblad.—Pharmaceutisch Weekblad, Amsterdam, 1916, v. 53.
Pharm, Ztg.—Pharmazeutisch Zeitung, Berlin, 1916, v. 61.
Pharm, Zentralh.—Pharmazeutische Zentralhalle fiir Deutschland, Dresden,
1916, v. 57.
Philippine J. Se.—Philippine Journal of Science, 1916, v. 11, Sec. A, B, O, and D.
Phil. Mag.—The London, Edinburgh, and Dublin Philosophical Magazine and
Journal of Science, 1916, v. 31 and 32.
Physiol. Abstr.—Physiological Abstracts, London, 1916, v. 1.
110095°—19-——_2
18
Pract. Drug.—Practical (The) Druggist and Pharmaceutical Review of Re- —
views, New York, 1916, v. 34.
Practitioner (The), London, 1916, v. 96 and 97.
Proc. Nat. Acad. Sci—Proceedings of the National Academy of Sciences, Wash-
ington, 1916, v. 2.
re Roy. Soe. Lond.—Proceedings of the Royal Society, London, 1916, v. 89 and
Proc. Soc. Exper. Biol. and Med.—Proceedings of the Society for Experimenta!
Biology and Medicine, 1916, v. 138.
Proceedings of State pharmaceutical associations:
Proc. Alabama Pharm. Assoc. 1916.
Proc. California Pharm. Assoc. 1916.
Proc. Connecticut Pharm. Assoc, 1916.
Proc. Florida Pharm. Assoc. 1916.
Proc. Georgia Pharm. Assoc. 1916.
Proc. Illinois Pharm. Assoc. 1916.
Proc. Indiana Pharm, Assoc. 1916.
Proc. Kansas Pharm. Assoc. 1916.
Proc. Louisiana Pharm. Assoc. 1916.
Proce. Maryland Pharm. Assoc. 1916.
Proc. Massachusetts Pharm. Assoc. 1916.
Proc. Michigan Pharm. Assoc. 1916.
Proc. Minnesota Pharm. Assoc. 1916.
Proc. Missouri Pharm. Assoc. 1916.
Proc. Nebraska Pharm, Assoc. 1916.
Proc. New Hampshire Pharm. Assoc. 1916,
Proce. New Jersey Pharm. Assoc. 1916.
Proc. New York Pharm. Assoc. 1916.
Proe. North Carolina Pharm. Assoc. 1916.
Proc. North Dakota Pharm. Assoc. 1916.
Proe. Ohio Pharm. Assoc. 1916.
Proc. Pennsylvania Pharm. Assoc. 1916.
Proc. South Carolina Pharm, Assoc. 1916.
Proc. South Dakota Pharm. Assoc. 1916.
Proc. Texas Pharm. Assoc. 1916.
Proc. Utah Pharm. Assoc. 1916.
Proc. Washington Pharm. Assoc. 1916.
Proc. West Virginia Pharm. Assoc. 1916.
Proc. Wisconsin Pharm. Assoc. 1916.
Public Health Rep.—Public Health Reports, Washington, 1916, v. 31, Nos. 1-52.
Pure Products, New York, 1916, v. 12.
Répert. pharm.—Repertoire de pharmacie, Paris, 1916, v. 28, part 1.
Rep. Chem. Lab. Am. M. Assoc.—Annual Reports of the Chemical Laboratory
of the American Medical Association, Chicago, 1916, v. 9.
Re}. Connecticut D. and F. Com.—Report of the Connecticut Dairy and Food
Commissioner, 1916.
“Rep. District of Columbia Health Off.—Report of the Health Officer of the
District of Columbia, 1916.
Rep. Florida Bd. Health.—Twenty-eighth Annual Report of the State Board
of Health of Florida, 1916.
Re}. Florida Dept. Agric.—Fourteenth Biennial Report of the Department of
Agriculture of the State of Flovida, 1915 and 1916.
Rep. Kansas Bd, Health.—Highth Biennial Report of the Kansas State Board
of Health, 1916.
19
Rep. Maine Agric. Exper. Sta.—Thirty-second Annual Report of the Maine
Agricultural Experiment Station, 1916.
Rep. Massachusetts Bd. Health.—Second Annual Report of the State Depart-
ment of Health of Massachusetts, 1916.
Rep. Missouri F. and D. Com.—Annual Report of the Food and Drug Commis-
_ sioner to the Governor of the State of Missouri, 1916.
Rep. Nebraska F., D., D., and O. Com.—Biennial Report of the Food, Drug,
Dairy, and Oil Commission to the Governor of the State of Nebraska, Lin-
coln, 1914-1916.
Rep. Nevada Agric. Hxp. Sta.—Report of the Nevada Agricultural Experiment
Station, 1916,
Rep. New Jersey Dept. Health.—Fortieth Annual Report of the Department
of Health of the State of New Jersey, 1916.
Rep. North Dakota Agric. Exper. Sta.—Report of the Director of the North
Dakota Agricultural Experiment Station, 1916.
Rep. North Dakota F. Com.—Twelfth Annual Report of the North Dakota
Food Commissioner and State Chemist, 1915.
Rep. Rhode Island F. & D. Com.—Seventh Annual Report of the Board of
Food and Drug Commissioners, Rhode Island, 1916.
Rep. South Carolina Com. Agric. Com. & Ind.—Thirteenth Annual Report of
the Commissioner of Agriculture, Commerce, and Industries of the State of
South Carolina, Columbia, 1916.
Rep. South Dakota F. & D. Com.—Sixteenth Annual Report of the Food and
Drug Commissioner of South Dakota, 1916.
Rep. Tennessee F. & D. Dept.—Annual Report of the Food and Drug De-
partment, State of Tennessee, 1916.
Rep. Therap. Res. Com.—Annual Report of Investigations of the Therapeutic
Research Committee of the Council on Pharmacy and Chemistry of the
American Medical Association, Chicago, 1916, v. 5.
Rep. Utah D. & F. Com.—Tenth Biennial Report of the State Dairy and
Food Commissioner of the State of Utah, 1915-1916, Salt Lake City, 1916.
Rep. Virginia D. & F. Com.—Quarterly Report of the Dairy and Food Com-
missioner of Virginia, Richmond, 1916.
Rep. Virginia D. & F. Com.—Annual Report of the Dairy and Food Com-
missioner of Virginia, Richmond, 1916, Bull. No. 63.
Rep. Wyoming D. F. and O. Com.—Twelfth Annual Report of the Dairy, Food
and Oil Commissioner, 1916.
Retail Druggist, Detroit, 1916, v. 23.
Rey. farm.—Revista farmaceutica, Buenos Aires, 1916, v. 59.
Rocky Mountain Druggist (The), Denver, 1916, v. 30.
Schweiz. Apoth.-Ztg—Schweizerische Apotheker-Zeitung, Ziirich, 1916, v. 54.
Science, New York, 1916, v. 44.
Sci. Am.—Scientific American, 1916, v. 114 and 115.
Sci. Papers Bur. Stand.—Scientific Papers of the Bureau of Standards, U. S.
Department of Commerce, 1916.
Simmons’ Spice Mill, New York, 1916, v. 39.
Southern Med. J.—Southern Medical Journal, 1916, v. 9.
Southern Pharm. J.—Southern (The) Pharmaceutical Journal, Dallas, 1916,
v. 8, Nos. 5 to 12; v. 9, Nos. 1 to 4.
Spatula (The), Boston, 1916, v. 22 and 23.
S. R. A.-Chem.—Service and Regulatory Announcements, United States De-
partment of Agriculture, Pureau of Chemistry, 1916.
Stidd. Apoth.-Ztg.—Siiddeutsche Apotheker-Zeitung, Stuttgart, 1916, v. 56.
Svensk Farm. Tidskr.—Svensk Farmaceutisk Tidskrift, Stockholm, 1916, v. 20.
20
Tech. Papers Bur. Stand.—Technologic Papers of the Bureau of Standards,
U. S. Department of Commerce, 1916.
Therap. Gaz.—Therapeutie Gazette, Detroit, 1916, v. 40.
Tr. Am. Inst. Chem. Eng.—Transactions of the American Institute of Chemi-
cal Engineers, New York, 1916, v. 9.
U. S. Naval Med. Bull.—United States Naval Medical Bulletin, 1916, v. 10.
Virginia Pharmacist (The), Richmond, 1916, v. 1.
Western Druggist (The), Chicago, 1916, v. 38.
West. Pennsylvania Ret. Drug—Western Pennsylvania Retail Druggist, 1916.
Wis. Med. J.—Wisconsin (The) Medical Journal, Milwaukee, 1916, v. 14 and 15.
Wyoming (The) Farm Bull.—University of Wyoming Agricultural College and
United States Department of Agriculture cooperating, 1916, v. 6, Nos. 2, 3, 4,
5 and 6.
Yearbook of Pharmacy (and Transactions of the British Pharmaceutical Con-
ference), London, 1916.
Zentralbl. Biochem. u. Biophys.—Zentralblatt fiir Biochemie und Biophysik,
Berlin, 1915, v. 18.
Ztsechr. anal. Chem.—Zeitschrift fiir analytische Chemie, Wiesbaden, 1916, v. 55.
Ztschr. angew. Chem.—Zeitschrift fiir angewandte Chemie, Leipzig, 1916, v. 29.
Ztschr. anorg. Chem.—Zeitschrift ftir anorganische und allgemeine Chemie,
Leipzig, 1916, v. 97 and 98.
Ztschr. Unters. Nahr.- u. Genussm.—Zeitschrift fiir Untersuchung der
Nahrungs- und Genussmittel, Berlin, 1916, v. 31.
2. TITLE ABBREVIATIONS—PHARMACOPGIAS AND NONOFFICIAL
STANDARDS.
Ph. Arg. I. acional Argentina, Primera edicion, 1898.
Ph. Austr. VIII.—Pharmacopea Austriaca, editio octava, 1906.
Ph. Belg. I1I.—Pharmacopea Belgica, editio tertia, 1906.
Ph. Brit. V.—British Pharmacopeia, 1914.
Ph. Chil. I—Farmacopea Chilena, 1886.
Ph. Dan. VII.—Pharmacopeia Danica, 1907.
Ph. Fenn. V.—Pharmacopcea Fennica, edito quinta, 1914.
Ph. Fr. V.—Codex Medicamentarius Gallicus, Pharmacopée Francaise, 1902.
Ph. Germ. V.—Deutsches Arzneibuch, 5, Ausgabe, 1910.
Ph. Helv. IV.—Pharmacopcea Helvetica, editio quarta, 1907.
Ph. Hisp. VII—Farmacopea Oficial Espanola, séptima edicion, 1905.
Ph. Hung. III].—Pharmacopeea Hungarica, editio tertia, 1909.
Ph. Ital. I1I.—Farmacopea ufficale del regno d’Italia, Terza edizione, 1909.
Ph. Japon. I1Il.—The Pharmacopeia of Japan, 1906 (English translation,
1907).
Ph. Mex. [V.—Nueva Farmacopea Mexicana, cuirta edicié6n, 1904,
Ph. Ndl. 1V.—Pharmacopoea Nederlandica, editio quarta, 1905.
Ph. Nory. 1VY.—Pharmacopcea Norvegica, editio quarta, 1913.
Ph. Ross. VI.—Pharmacopcea Rossiea, sixth edition, 1910.
Ph. Serv. I1.—Pharmacopeeia Serbica, editio secunda, 1908,
Ph. Svee. IX. 908.
Ph. Ven. I.—Farmacopea Venezolana, 1898.
U. S. P. VIII and IX.—Pharmacopeia of the United States, 8th Rey., 1905
and 9th Rey. 1916.
I’. IIT and I1V.—The National Formulary, 3rd Rey., 1906, and 4th Rey., 1916,
N. N. R.—New and Nonoflicial Remedies, Chicago, 1914.
B. P. C.—British Pharmaceutical Codex, London, 1911.
DIGEST OF COMMENTS ON THE PHARMACOPEIA OF THE UNITED
STATES OF AMERICA AND ON THE NATIONAL FORMULARY.’
I. GENERAL COMMENTS.
I. LEGAL STATUS AND DEVELOPMENT.
1, PURE FOOD AND DRUG LAWS.
Anon.: A synopsis of the food and drug laws enacted by Congress
and the various State legislatures during the year 1915.—Am. Food
J. 1916, v. 11, p. 59-63.
_ Anon.: A book review calls attention to a volume entitled “ State
Pure Drug Laws Enacted Since the Passage of the National Food
and Drugs Act, June 30, 1906, with a Reprint of Said Act as
Amended.” The volume is published by The Proprietary Associa-
tion of the National Wholesale Druggists’ Association.—Northwest-
ern Druggist (The), 1916, No. 3, p. 45.
Beal, J. H.: In cigars qa able legislation as an aid to main-
tain pharmacy, the author states that the terms used in the draft-
ing of legislative measures should, as far as possible, be self-inter-
preting. Such general terms as “derivatives,” “synthetic sub-
stances,” “physiological equivelants,” “ habit-forming drugs,” “ nar-
cotic drugs,” “ poisons,” “ poisonous drugs,” etc., should be avoided,
unless accompanied by qualifications and Seeuaicda which clearly .
limit the sense in which they are to be understood.—J. Am. Pharm.
Assoc. 1916, v. 5, p. 256-259; see also Pharm. Era, 1916, v. 49, p.
105; Drug. Circ. 1916, v. 60, p. 698.
England, J. W.: Attention is directed to the fact that legisla-
tion of recent years has given the power of making rules and regu-
lations for carrying out the provision of various acts to administra-
tive departments of the Government, and that there is great danger
of this power being abused through the zeal of such departments in
_ attempting to make a public reputation for efficiency, that these de-
partments may become unreasonable and bureaucratic and frame
regulations that would be a serious handicap to the drug trade as
2 whole—J. Am. Pharm. Assoc. 1916, v. 5, p. 1163-1164.
Alsberg, C. L.: In the opinion of the Bureau of Chemistry, an
article sold under a name recognized in the index, but not appearing
in the text, of the United States Pharmacopeia is a drug within the
— wa ——
a aetinisovigt Aawaniticd for publication Feb. 8, 1919,
(21)
99
_
meaning of section 6 of the Federal food and drugs act. It must,
therefore, comply with the standard of strength, quality or purity
as determined by tests laid down in the U. S. P. official at the time
of inyestigation.—S. R. A. Chem. 1916, No. 16, p. 30.
Anon.: To attempt the correction of the shortcomings in the ob-
servation, interpretation, and application of pharmacy laws an:l
supplemental statutes, the National Drug Trade Conference, in
December, 1915, appointed a special committee on the interpreta-
tion and enforcement of food and drug laws.—N. A. R. D. J. 1916,
v. 22, p. 1069.
La Wall, Chas. H.: An enumeration of some specific instances in
which the pharmacist comes in contact with the food laws.—Proc.
Pennsylvania Pharm. Assoc. 1916, p. 254-259.
Editorial: Federal food and drug acts vigorously enforeed. A
review of the cases tried during the fiscal year for the violation of
these laws.—Apothecary (The), 1916, v. 18, No. 11, p. 15.
Anon.: In a comparison of the insecticide aet and the food and
drugs act, it is stated that the citizen may not be defrauded by the
sale of a worthless louse killer, but his Government offers him little
protection against the sale of a worse-than-worthless consumption
“ cure.”—J. Am. M, Assoc. 1916, v. 67, p. 2019-2020.
Du Bois, Gustave: An article pointing out the necessity of proper
tariff legislation to influence the development of the manufacture of
medicinal chemicals in the United States——J. Ind. & Eng. Chem.
1916, v. 8, p. 1156-1158.
Rusby, H. H.: A criticism of a ruling by the Federal court for
the northern district of Illinois permitting the sale of charlock as
mustard.—Drug. Cire. 1916, v. 60, p. 394-395.
Editorial: A discussion of the appropriateness of the New York
patent medicine ordinance. It is thought to be unjust—Am. Drug-
gist, 1916, v. 64, No. 1, p. 21.
2. SALE AND USE OF POISONS.
Editorial: A review of an article on the sale and use of poisons
emphasizing the need for a national poison law.—J. Am. M. Assoc.
LLOg, Vo. 00.0, gL LOL,
Anon.: The National Association of Retail Druggists, at its last
annual meeting, passed a resolution favoring an amendment to the
postal laws that will make it possible to send medicines containing
poisons through the mails under such restrictions as to packing and
so on as will prevent their possible injury to the mails or to those
handling the same.—N. A. R. D. J. 1916, v. 22, p. 1851.
Anon.: Admission to the domestic mails of medicinal products
which contain poisons in only sufficient quantity and form in com-
q 93
FRiniation with other ingredients to be used exclusively as a curative
remedy or remedial substances, and which are not dangerous or in-
jurious to life, safety, health, or property, is proposed in a bill
recently introduced into the House of Representatives by Representa-
tive Griffin of New York. The article mailed is to bear the label
or superscription of. the manufacturer thereof or dealer therein, or
of the licensed physician, pharmacist, dentist, or veterinarian pre-
paring or prescribing the same.—J, Am. M. Assoc. 1916, v. 66. p. 826.
Anon.: A resolution to amend the present regulations to permit
the shipping of poisons by mail.—Proc. North Dakota Pharm. Assoc.
1916, p. 38-89.
-_ Anon.: A review of reprint No. 330 from the Public Health Re-
ports, United States Public Health Service, states that the publica-
tion is a valuable and convenient reference book of all narcotic and
poison laws and, therefore, should be of particular interest to all
branches of the drug trade—J. Am. Pharm. Assoc. 1916, v. 5, p.
899; also J. Am. M. Assoc. 1916, v. 67, p. 442.
Editorial: The use of poison has always been a prominent method
employed by those who voluntarily destroy their own lives. Ac-
cording to the Bureau of Census, the number of suicides reported
in 1914 was 10,933, or 16.6 per hundred thousand population. Of
this number, 3,000 accomplished self-destruction by the use of
poison.—J. Am. M. Assoc. 1916, v. 66, p. 428.
Eberle, E. G.: In a discussion of the inconsistencies in drug legis-
lation it is stated that S. W. Lambert and H. 8S. Patterson in re-
porting on the suicides by poisoning in New York City during five
years classify the cases as follows: Paris green and arsenic, 48;
phenol, 154; opium and morphine, 29; mercuric chloride, 104; illu-
minating gas, 1,554, other poisons, 237.—J. Am. Pharm. Assoc. 1916,
v. 5, p. 126-197.
Anon.: A reprint of the new decree governing the sale and use
of poisons in France.—J. pharm. et chim. 1916, v. 14, p. 247-255,
279-287.
3. SALE AND USE OF NARCOTIC DRUGS.
Hilton, S. L.: The narcotic drug content of a number of the N. F.
preparations has been reduced in order to comply with the excep-
tions of section 6 of the Harrison law.—Bull. Pharm. 1916, v. 30,
p. 281.
Van Zandt, C.: A discussion of the narcotic question with respect
to the entire world.—Rocky Mountain Druggist (The), Denver,
1916, v. 30, No. 10, p. 17-23.
Wilbert. M. I.: A review of recent legislation designed to restrict
the use of narcotic drugs.—Public Health Rep., 1916, v. 81, p. L14-
119,
24
Mandabach, P. A.: The Harrison Narcotic Law Catechism. An
explanation of the important features of the Harrison law in the
form of questions and answers.—Nat. Drug Clerk, 1916, v. 4, p.
66-67, 69; also Apothecary, 1916, v. 13, No. 2, p. 22-23.
Hoback, Fred H.: A discussion of the Harrison law, with special
reference to “dope” prescriptions—Virginia Pharmacist (The).
Richmond, 1916, v. 1. p. 13-14.
Noonan, Harry: A discussion of some of the incongruities of the
Harrison law.—Pract. Drug., 1916, v. 34, No. 3, p. 42.
Anon.: A new Treasury decision on the Harrison law requires that
the amount of narcotic per ounce or per tablet must be given on the
order form only when the preparations are not U. S. P. or N. F.—
Bull. Pharm., 1916, v. 30, p. 128.
Editorial: Attention is called to the fact that discrepancies in
accounting for small quantities of narcotic drugs will occur in the
most carefully regulated pharmacies owing to unavoidable loss in
dispensing.—Am. Druggist, 1916, v. 64, No. 1, p. 20.
Lederer, Ephriam: In a discussion of the Harrison narcotic act,
the author concludes that the law is fully justified and the slight
amount of trouble and inconvenience caused by its administration
should be cheerfully undergone, for the sake of the general welfare,
by those to whom the act applies—J. Am. Pharm. Assoc., 1916, v. 5,
p. 720-7238.
Craycroft, C. E.: Greater familiarity with the practical working
of the Harrison antinarcotic law is demonstrating the fact that great
good is being accomplished by its enforcement. Thousands of un-
fortunate habitués have taken treatment for their drug cravings and
have been cured thereof. There seems to be a general disposition to
feel that the law is proving a great success.—Proc. Texas Pharm.
Assoc., 1916, p. 12.
Editorial: In many ways the year’s experience with the Harrison
narcotic law is favorable to its continuation in its present form. Its
real effectiveness, however, appears to be much restricted by a recent
decision of the United States Supreme Court which holds that the
possession of narcotic drugs by persons not specifically authorized
to have them can not constitute the basis for a conviction on the
charge of conspiracy. The decision practically nullifies the language
of section 8 of the law which declares it to be unlawful) for any per-
son not authorized to have such drugs in his possession.—Pharm.,
Era, 1916, v. 49, p. 264.
Editorial: The good intentions of our lawmakers and the aims
and purposes of the Harrison antinarcotic law have been practically
nullified because of the fact that possession of narcotics by unlicensed
persons was not qualified in the law.—Pract. Drug., 1916, v. 34, No. 9,
p. 17-18.
25
Anon.: An editorial discussing the refilling of narcotic prescrip-
tions states that section 6 of the Harrison Act is wholly and in-
defensibly pernicious.—J. Am. M. Assoc. 1916, v. 67, p. 958.
Anon.: The concluding lines of section 6 of the Harrison narcotic
law are stated to be a joker which gives the Coca-Cola Co. a valuable
business asset and a monopoly in the distribution of dope—West.
Pennsylvania Ret. Drug. 1916, May, p. 10. $
Anon.: An editorial discussing State rights and State duties in
their relation to the Harrison narcotic law.—J. Am. M. Assoc. 1916,
v. 67, p. 37-388.
_ Anon.: A reprint of some of the bearigntle amendments of the Har-
rison narcotic law.—Oil, Paint & Drug Rep. 1916, v. 90, No. 24, p. 16.
Anon. : It is the belief of the National Drug Trade Conference that
amendments to the Harrison law during the present session of Con-
gress are inadvisable for the reason that the measure is now in
its formative period.—Bull. Pharm. 1916, v. 30, p. 2.
Anon.: A resolution passed by the National Association of Retail
Druggists reads as follows: * Resolved, That all efforts to amend the
Harrison law by the elimination of section 6 be fervently opposed,
and that, if any changes are contemplated in the law, we lend our
support to those measures which would tend to strengthen, rather
than weaken, the law.”—N. A. R. D. J. 1916, v. 22, p. 1351.
Bishop, Ernest S.: The two definite and urgent problems in the
regulation of the sale of habit-forming drugs are the suppression
of illicit and illegitimate traffic in narcotics and the handling of the
unfit who has become an addict, whether he be unfit through crim-
inality, inherent degeneration or deterioration, misfortune, or igno-
rance.—Oil, Paint & Drug Rep. 1916, v. 90, No. 26, p. 17.
Editorial: In a discussion of the regulation of the sale of narcotics.
it is stated that the first demand which should be made—the first
immediate necessity—the absolute essential to any intelligent action
tending to abolish the drug evil must be the complete facts as to
manufacture, distribution, importation, and exportation of opium
derivatives.—Oil, Paint & Drug Rep. 1916, v. 90, No. 26, p. 13.
Editorial: The cure for existing conditions as regards the dis-
tribution and ilhcit consumption of habit-forming drugs must be
found in the united action of not alone the Community, the State,
and the Nation, but in international agreement with border coun-
tries, in addition to which must be perfected some system of national
control either through the form of excise law or bonded warehouse
system or other safeguard, which shall follow the progress of the
narcotic from the time of its manufacture till its final distribution to
the individual.—Oil, Paint & Drug Rep. 1916, v. 90, No. 27, p. 13.
Beal, J. H.: As a corollary to making the legality or illegality of
the sales of intoxicating or narcotic preparations depend upon the
26
purposes for which they are sold, antiliquor and antinarcotic laws
should be reformed so as to provide suitable penalties for those who
obtain them either surreptitiously or otherwise than to use for their
proper and legitimate purposes. The penalties will then be fitted to
the criminal as well as to the crime.—Drug. Cire. 1916, v. 60, p. 700.
Editorial: In a discussion of pending legislation, it is stated that —
no one*State at present has a model narcotic law, even the Federal —
enactment has been tried in the courts and has been found wanting,
but in the serious consideration, and possible adoption of the best —
features of the laws now operative in the individual States lies a
wonderful opportunity for the eventual adoption of a narcotic
measure which shall err neither on the side of laxity nor in its radical
restrictions.—Oil, Paint & Drug Rep. 1916, v. 90, No. 20, p. 13.
Editorial: The willingness of the physician and pharmacist to
=scabe
ee ee Oe eae es
comply with the provisions of the Harrison antinarcotic law is indi- —
cated by the fact that considerably less than one-half of 1 per cent ©
of the prosecutions for infractions of the law were against men of
these professions—Drug. Circ. 1916, v. 60, p. 65-66.
Eberle, E. G.: In a short editorial, it is stated that the wording of
the Federal narcotic law clearly indicates that State cooperation was
expected and deemed essential for carrying out the moral end, but
this was not fully recognized until now. Many have opposed con-
templated State regulations, believing that these were simply dupli-
cate annoyances without accomplishing any more than could be effec:
tively done under the Harrison law. Such inaction is no longer
excusable and, as soon as possible, the State narcotic measures should
be so amended that they will apply to violations beyond the reach of
the Federal law.—J. Am. Pharm. Assoc. 1916, v. 5, p. 682-683.
Anon.: Resolutions empowering its committee on narcotic legisla-
tion to draft the State measure for regulating the prescribing and
distribution of habit-forming drugs in New York and other States
were adopted by the American Medical Editors’ Association at their
annual meeting held October 25, 1916.—Oil, Paint & Drug Rep. 1916.
v. 90, No. 20, p. 16.
Anon.: The New England Association of Boards of Pharmacy at
its annual meeting in Boston adopted resolutions announcing the
determination to suppress the sale of narcotic drugs within the juris-
diction of its members, and to close such stores as refuse to comply
with the State laws and regulations——Oil, Paint & Drug Rep., 1916,
v. 90, No. 26, p. 17.
Anon.: The continuous use of small doses of a narcotic drug is just
as capable of establishing a habit as in the case of larger doses.—
J. \m. M. Assoc., 1916, v. 66, p. 1156.
Newcomb, E. L.: The proper control of the use of narcotics in
small amounts is as important as the control of preparations con-
3
taining larger amounts—Proc. Minnesota Pharm. Assoc., 1916,
p- 56.
Anon.: One sad result of current legislation has been the de-
priving of addicts of narcotic supplies without any provision for
their adequate and humane care or cure—Am. J. Clin. Med., 1916,
y. 23, p. 972.
Editorial: The position of the drug addict varies with the view-
point of the observer. The police authorities see him as a criminal,
the alienist as a weakling or a degenerate, and the public as a habitué
and, all too frequently, a curse to himself and society in general.
The addict, however, sees himself as a sick man and one who needs
the attention of a friendly physician and, in his estimation, he needs
a cure and not the prolongation of further suffering—Pharm. Era,
1916, v. 49, p. 187.
McIver and Price: From an analysis of 147 cases of drug addic-
tion treated at the Philadelphia General Hospital, it was concluded
that, while the medical profession has had much to do with the
formation of the morphine habit, and in former years with the de-
velopment of the cocaine habit, it has had little or nothing to do
with the remarkable development and spread of the cocaine and
especially the heroin habit during the last few years—J. Am. M.
Assoc, 1916, v. 66, p. 476-480.
Editorial: Justice Cornelius I’. Collins is credited with the state-
ment that American firms are shipping drugs to Canada in quantities
vastly beyond the possible Canadian consumption and that these
drugs eventually find their way into the underworld and are re-
turned to the United States——Oil, Paint & Drug. Rep. 1916, v. 90,
No. 28, p. 13. For replies to the accusation of Justice Collins, see No.
24, p. 13, 16.
Anon.: Bulletin No. 2 issued by the publicity committee of the
Pennsylvania Pharmaceutical Association states that declarations
made by the jobbing and manufacturing interests indicate that the
total amount of narcotic drugs imported and sold has been reduced
about 80 per cent since the Harrison law has gone into effect.—J. Am.
Pharm. Assoc. 1916, v. 5, p. 181.
Anon.: The Illinois antinarcotic law is said to be superior to most
‘other measures of a similar nature, as it restricts the retail of nar-
cotics absolutely to registered pharmacists.—Bull. Pharm, 1916, v. 30,
2.
F Anon.: A review of reprint No. 330 from the Public Health Re-
ports states that this valuable pamphlet contains copies of the poison
and narcotic laws enacted by the several States, as well as data con-
cerning germane Federal statutes, and that the whole is made more
valuable by an extensive analytical index.—Drug. Circ. 1916, v. 60,
p. 493.
27
28
4. SALE AND USE OF HOUSEHOLD REMEDIES.
Anon.: A summary of the general results of the 1914 census of
manufactures for the production of druggists’ preparations, patent
and proprietary medicines and compounds, and perfumery and cos-
metics has been issued by Director S. L. Rogers, of the Bureau of the ~
|
|
i
3
=
Census, Department of Commerce. It consists of a statement of the —
quantities of the anesthetic and narcotic drugs used as ingredients of —
the products manufactured. The figures are preliminary and are
subject to such change and correction as may become necessary upon
further examination of the original returns—N. A. R. D. J. 1916,
vy. 22, p. 1249.
Beal, James H.: Report of the commission on proprietary
medicines of the American Pharmaceutical Association—J. Am.
Pharm. Assoc. 1916, v. 5, p. 1874-1381, 1882-1389; Nat. Druggist,
1916, v. 46, p. 406-410; N. A. R. D. J. 1916, v. 23, p. 406-411.
Anon.: During the year the Proprietary Association of “America
has been engaged in examining the preparations of various manufac-
turers with the idea of excluding from the association such members
as do not comply with the standard of ethics officially adopted. At
the annual convention held in New York, it was reported that 1,078
preparations had been submitted for examination and that 611 of
these had been passed upon.—Bull. Pharm. 1916, v. 30, p. 260.
Anon.: A committee of the American Medical Association has
requested President Wilson to appoint a commission to investigate
the patent-medicine business, which, they state, is to a large extent an —
evil of national scope-—Pharm. Era, 1916, v. 49, p. 150.
Gilkey, Harry A.: In an article entitled “ Fake preparations ” the
author states that home treatment of ailments is hazardous at best,
and certainly is not to be encouraged. The actual need for any
medicine, for that matter, and the proper general treatment should
only be determined by a physician. Nevertheless, those who are fair-
minded must admit that there are many preparations of merit
among the patent and proprietary remedies.—Northwestern Drug-
gist (The), 1916, v. 17, No. 4, p. 39.
Editorial: Without considering the question of self-medication,
it appears that the greatest menace to the public from proprietary
medicines arises from fraudulent advertising and the purely com-
mercial exploitation which is back of the sale of some remedies of
this class—Northwestern Druggist (The), 1916, v. 17, No. 8, p. 24.
Editorial: An argument in favor of the use of standard pro-
prictary remedies.—Southern Pharm. J. 1916, v. 8, p. 1066.
Merrill, Theodore C.: A discussion of some of the important
aspects of the use of proprietary medicines in the home treatment
of children.—Am. J. Public Health, 1916, v. 6, p. 479-485.
29
Alsberg, Carl L.: The mother in giving proprietary remedies is
governed by false ideas of economy and convenience, and the truth
‘should be presented to her by all possible means. The physician his
a public and a professional duty in the education of the public
on this vital subject. The dealer is concerned solely from the busi-
ness standpoint. ‘The solution lies in an educated oe opinion.—
J. Am. M. Assoc. 1916, v. 66, p. 57.
Anon.: The Garona iat the right and it is its duty to protect
the uninformed public against the flagrant evil of the patent-medicine
traffic. It should protect the public against advertisements that are
framed to suggest or create ailments with their attendant miseries;
it should protect the public against being deluded by false promises
of cure; against drugs that may and do work positive harm; against
the veil of mystery that makes abuses possible—J. Am. M. Assoc.
1916, v. 66, p. 756.
Editorial: The strong effort of the American Medical Associa-
tion to discourage the use of patent and proprietary remedies does not
seem as yet to have any great effect since, in the five-year period
(1909-1914), the increase in the number of producing establishments
amounts to 8.7 per cent, while the increase in the value of the prod-
ucts amounts to 26.1 per cent.—Midl. Drug. 1916, v. 50, p. 479.
Editorial: There is no reason why the proprietary remedy should
be denounced in a wholesale way. There are a great many useful,
convenient, and beneficent remedies on sale that are a blessing to
the community. The inconvenience and suilering that would be
caused if they could no longer be obtained is inconceivable. And
the differences between a popular and an “ ethical ” remedy is grow-
ing less as time goes on.—Northwestern Druggist (The), 1916, v.
17, No.1, p. 21.
Anon.: In the 1915-16 report of the A. Ph. A. Commission on
Proprietary Medicines, it is stated that it is the professional right
of the pharmacist, sanctioned by custom and tradition, to keep
proprietary remedies in stock whether manufactured by himself
or by others and to supply them to the general public on demand.
In meeting the demand for ready-made or package remedies the
pharmacist should refrain from usurping the proper functions of
the physician, especially in regard to diagnosis.—Pharm. Era, 1916,
v. 49, p. 424.
Boberg, Otto: The character of the so-called prescription reme-
dies should be denounced by the pharmacist and the methods of ad-
vertising the same should be disapproved.—Proe. Wisconsin Pharm.
Assoc. 1916, p. 57-58.
Robin, D. N.: A discussion of the possibility of a national line
of nonsecrets, to be prepared by the individual, but with common
30
ownership of copyrighted labels—J. Am. Pharm. Assoc. 1916, v. 5,
697.
© Anon.: An editorial discussing objectionable features in the ad-
vertising of patent medicines.—J. Am. M. Assoc. 1916, v. 67, p. 957-
958, 1603.
Anon.: An enumeration of the methods by which secret reme-
dies do harm to those using them, together with recommendations
for overcoming this evil—Rep. North Carolina Bd. Health, 1915—
16, p. 51-58.
Editorial: The “Open formula” bugbear. Slowly but surely the
public is coming to realize that one of the most effective ways of
discouraging fraud in the “patent medicine” business will be to
demand that the names and quantities of the potent ingredients of
all “ patent medicines” be declared on the label—J. Am. M. cai |
1916, v. 67, p. 752.
Editorial: As druggists see it, the advantage to the manufacturer
of putting up preparations according to a secret formula is that he
can put in or leave out any ingredient he chooses, as the conditions —
of the market, his respect for the law, or other circumstances may
dictate—J. Am. M. Assoc. 1916, v. 67, p. 884.
Editorial: A bill to prohibit fraudulent advertising in the Dis-
trict of Columbia was signed May 29. The bill is designed, among
other things, to prevent quack doctors and fake dentists from ad-
vertising their fraudulent nostrums, impossible methods, and al-
leged results——J. Am. M. Assoc. 1916, v. 66, p. 1862.
News Note: The Department of Health of New York labels pat-
ent medicines. The “Goldwater registry law,” requiring that all ©
patent medicines have a proper declaration label on the outside or
that the seller declare the contents to the board of health, went into
sc tales
yore
effect on January 1, 1916. Several days before this date 300 in- |
spectors from three bureaus of the department of health started to —
canvass 2,494 drug stores in Greater New York and place labels on |
5,000,000 packages of patent medicines.—J. Am. M. Assoc. 1916, v.
66, p. 125.
Anon.: Bills which aim to compel patent medicine manufacturers —
to make public the exact composition of their nostrums have been
introduced in the New York Legislature simultaneously by Assem-—
blyman Fertig and Senator Hamilton.—J. Am. M. Assoe. 1916, v.
66. p. 824.
Mouschinski, M.: An account of the use of certain domestic reme-
dies in the Caucasus.—Chem. Abstr. 1916. v. 10, p. 1908, from Phar-
mavzeutizeski J. 1915, p. 487; see also J. pharm. et chim, 1916, vy. 13,
p. 162-164,
ol
_ Anon.: Under the caption “Old women’s remedies” the author
discusses a number of folk remedies for common ailments.—Pharm.
J. 1916, v. 96, p. 495-496.
_ Anon.: A list of some of the European proprietaries which have
appeared on the market recently-—Drug. Cire. 1916, v. 60, p. 34.
Anon.: A book review of a volume entitled Quack Medicines,
published by the Dutch Society for Combatmg Quackery, states that
the analyses of 586 different proprietary medicines are given.—
Chem. & Drug. 1916, v. 88, p. 121.
Anon.: Notes on the composition of some nostrums.—N. A. R. D.
J. 1916, v. 22, p. 788-792, 837-839, 1073 from “ Medical Frauds,”
compiled by the Indiana Board of Health.
Anon.: A list of aleoholic medicma) preparations for the sale of
which the United States Hquor dealer’s tax is required.—Virginia
Pharm. 1916, v. 1, p. 73-77.
Johnson, Alma K.: A compilation of the results of the analyses
of a number of widely advertised nostrums and patent medicines
preceded by a discussion of the patent-medicine business.—Bull.
North Dakota Exper. Sta. F. Dept. 1916, v. 4, No. 9, p. 196-242.
Anon.: The United States Supreme Court has decided that the
Sherley amendment to the Federal pure food and drug laws is
valid.—Public Health Rep. 1916, v. 31, p. 107.
5. DRUG-INSPECTION WORK.
Guigues, P.: An account of the inspection of pharmacies con-
ducted in the days of the ancient Arabs.—Bull. se. pharmacol, 1916,
v. 23, p. 108-118.
Congdon, Leon A.: The 150 drug stores ae were classified
as follows: Good, 39; good to fair, 22; fair, 87; poor, 2—Bull. Kan-
sas Bd. Health, 1916, v. 12, p. 5.
Adams, F. A.: The lack of uniformity in pharmaceutical prepara-
tions 1s attributed to three causes, namely, lack of consideration in
the quality of materials used, in familiarity with the preparation
being compounded, and carelessness in manipulation.—Proe. Cali-
fornia Pharm. Assoc. 1916, p. 63-65,
_ Diekman, George C.: A discussion of the results obtained in the
examination of a number of drugs for the purpose of showing the
necessity for testing all official drugs and chemicals.—Proc. New
York Pharm. Assoc. 1916, p. 246-250.
Sayre, L. E.: A report of the results of the examination of a
large number of samples of crude drugs. Practically all of the sam-
ples were of good quality.—Bull. Kansas Bd. Health, 1916, v. 12,
p. 9-15.
52
Vanderkleed, C. E.: Report of the Committee of the A. Ph. A.
on Qualtiy of Medicinal Products.—J. Am. Pharm. Assoc. 1916, v. 5,
p. 532-545,
Lea, E. J.: Some of the tablets sa capsules examined were
found to be short in weight.—Bull. California Bd. Health, 1916, v.
11, p. 421.
ee E. J.: The results obtained in the analyses of coinsicsodaal |
samples of aspirin and veronal indicate that these drugs are still - |
sold in the adulterated form.—Bull. California Bd. Health, ah |
y. 11, p. 484.
Ekeléy, John B.: Of 80 samples of drugs examined, 20 were re-
jected.—Bull. Colorado Bd. Health, 1916, p. 19.
Street, John Phillips: Results = the examination of Aaa from |
the stocks of dispensing physicians. Of 41 samples of tablets, 8, or
20 per cent, were below standard, while of 12 samples of soli 1,4
or 60 per cent, were below standard.—Rep. Connecticut Agric. Exper. —
Sta. 1916, part 4, p. 229-248.
Woodward, W. C.: Of 52 samples of drugs examined, 5 were adul-
terated.—Rep. District of Columbia Health Off. 1916, p. 27. .
Barnard, H. E.: Of 407 samples of drugs examined, 41 were re-
jected because they did not comply with the U. S. P. standards— __
Bull. Indiana Bd. Health, 1916, v. 19, p. 2, 15, 39, 52, 68, 76, 88, 100,
112, 125, 136, 184.
Congdon, Leon A.: Of 47 crude and powdered drugs examined, 5
were rejected.—Rep. Kansas Bd. Health, 1916, p. 183. |
Lythgoe, Hermann C.: Of a total of 874 drugs examined during —
the year, 177 were found to be adulterated.—Rep. Massachusetts Bd.
Health, 1916, p. 450.
Todd, A. R.: Of 356 samples of drugs examined, 155 were re-
jected.—Bull. Michigan D. & F. Dept. 1916, No. 248-249, p. 10, 16,
19, 20.
Tice, William G.: Of a total of 503 samples of drugs examined, 141
were below standard.—Rep. New Jersey Dept. Health, 1916, p. 72.
K’we, Geo. E.: Of the 214 samples of crude drugs assayed in the —
laboratories of the H. K. Mulford Co., 156, or 72.9 per cent, were
above the U. S. P. standard.—Proc. Pennsylvania Pharm. Assoc.
1916, p. 119.
Frary, Guy G.: Seventeen of 76 samples of various toilet prepara-
tions examined contained methyl alcohol—Rep. South Dakota F. &
D. Com. 1916, No. 16, p. 154-162.
Kiskew, Harry L.: Of 181 samples of drugs examined, 67 were re-
jected.—Rep. Tennessee F. & D. Dept. 1916, p. 16.
Beckers, W.: A report on the results of an examination of cap-
stiles of copaiba and sandalwood, respectively, purchased in Germany.
An abstract.—C. U. C. P. Alumni J. 1916, v. 23, p. 186.
a
33
6. THE PHARMACOPGIA AS A LEGAL STANDARD.
s Weesndards for the tientity atid Saisie of drugs. Hee it. may
e observed that the U. S. P. IX will be noteworthy for its attempt
to satisfy these requirements and for its consequent aim at scientific
accuracy —Am. Druggist, 1916, v. 64, No. 8, p. 23.
a Editorial: Druggists should take particular pride in the fact that
the two books on which their professionalism is based are standards
in every sense of the word and vested with the authority of law.
Nothing could more formally fix the status of pharmacy.—Bull.
Pharm. 1916, v. 30, p. 263.
Editorial: Since the Pharmacopeia is now a legal standard, it
should not be made official until a year after its publication. The
fact that there was an interval of only a few months between the
appearance of the Pharmacopeeia and the date when it became official
is characterized as being not only stupid but mean and dishonest.—
Critic and Guide, 1916, v. 19, p. 362-363.
Beringer, George M.: A cursory review tracing the evolution of
the Pharmacopeia from a book of formulas to that of a book of
standards, fulfilling the important function of serving as the legal
authority for drugs and safeguarding the entire country against
adulteration—Pennsylvania Med. J. 1916, v. 19, p. 759.
Editorial: We believe that it is necessary for the several State legis-
latures to take such action as will make the latest editions of the
U. S. P.and N. F. official, even though the law in naming the stand-
ard might designate a future edition, as it has been held unconstitu-
tional to designate as a standard a publication which does not exist.—
Midl. Drug. 1916, v. 50, p. 481.
Editorial: It seems that it will be necessary for Congress to take
action before the new Pharmacopeeia will be official. Even then, it is
doubtful if the book will be official outside of the District of Colum-
bia, the island possessions, the Panama Canal Zone and Alaska, un-
less ratified by the legislatures of each State—Pract. Drug. 1916,
v. 34, No. 8, p. 18.
7. GENERAL PRINCIPLES TO BE FOLLOWED IN REVISING THE PHARMACOPGIA.
Beringer, George M.: To revise the Pharmacopeeia so that its
standards shall properly fulfill the added responsibility of its desig-
nation as a legal standard has been the paramount thought of the re-
visers.—Am. Druggist, 1916, v. 64, No. 8, p. 23.
— ——-:110095°—19 —3
34
8. PUBLICATION AND €ONTROL.
Anon.: The matter of Federal control of the U. S. P. and N. F. anc
other pharmaceutical affairs should be of vital concern to the Unitec
States authorities, as it has been preven that the drug feature of th
food law is constitutional, and that many of the States have been, and
are amending their State laws to meet the requirements of the drug
end of the national law.—Nat. Drug Clerk, 1916, v. 4, p. 181.
Editorial: In a short discussion of Government revision of the
Pharmacopeeia, it is stated that until we have a department of public
health at Washington, or at least a bureau well organized and
equipped to handle the business which would come before such a de
" partment, it does not seem likely that the Government will undertake
the publication of the Pharmacopeeia.—Drug. Cire. 1916, v. 60, p. 530.
Kaiser, W. F.: Report of Wisconsin Pharm. Assoc. Com. on U. S,
P. In the discussion, T. H. Potts of the N. A. R. D. says: “We
should petition Congress to take entire charge of the revision of the
U.S. P. and take it out of the hands of the board of trustees.”—Proe
Wisconsin Pharm. Assoc. 1916, p. 40.
Editorial: It is suggested that the U. S. P. be taken over by the
American Medical Association and henceforth published by it, since
all the publications of this society are gotten out in excellent style,
are complete, correct, and up to date—Critic and Guide, 1916, v. 19,
p- 239.
9. THE PHYSICIAN AND THE PHARMACOP@IA.
Anon.: An editorial review of the U. S. P. IX states that the
Pharmacopeia is not a book of standard remedies, but is a book of
standards for drugs. Being prepared mainly by pharmacists to meet
the need of pharmacists, it contains much matter of little interest te
physicians and entirely foreign to scientific medicine—J. Am. M.
Assoc. 1916, v. 67, p. 750-751.
Remington, J. P.: To the medical profession the great value of
the Pharmacopceeia has been and always will be the standardizatio
of the drugs and preparations in order that the physician may always
have preparations of uniform strength upon which he can depend for
the treatment of disease ——Proc. Pennsylvania Pharm. Assoc. 1916, p.
136. .
Whelpley, H. M.: More medical work in pharmacopeeial revision is
desirable, and pharmacists should urge physicians to learn more about.
the Pharmacopeeia and give it greater attention in the medical
schools.—Western Druggist (The), 1916, v. 38, p. 139.
Scoville, Wilbur L.: The addition of abbreviations to the U.S. P.
is obviously intended for the use of physicians, but one wonders how
much attention they are likely to pay to it—Bull. Pharm, 1916, y. 30,
p. 279.
39
Fantus, Bernard: Prescription writing in English. An argument
in favor of prescription writing in English illustrated by type pre-
_ scriptions and variations in the Latin as found in the Pharmacopoia
of the United States and in foreign pharmacopeias.—J. Am. M.
Assoc. 1916, v. 66, p. 1696-1698.
10. VALUE OF CRITICISM.
Blue, Rupert: As a result of the untiring efforts of the council
on pharmacy and chemistry of the American Medical Association
for more than a decade, our knowledge of the useful remedies has
been increased, the Pharmacopcia improved, and the physicians’
armamentarium made more serviceable-—J. Am. M. Assoc. 1916,
v. 66, p. 1960.
Thum, John K.: A review of Hygienic Laboratory Bulletin No.
105, in which it is stated that the publication has been of much
benefit to those directly interested in the revision of the U. S. P.
and N. F. Attention is also called to the remarks of Tschirch in this
connection, namely, “ That a successful revision is dependent on
a complete and perfect review of the literature pertaining to phar-
macy and materia medica.”—Am. J. Pharm. 1916, v. 88, p. 227-228.
Eberle, E. G.: In a review of the U. S. P. [X and N. F. IV, the
author states that the constructive assistance rendered by the Hy-
gienic Laboratory, United States Public Health Service, in com-
piling the Digest of Comments on the United States Pharmacopemia
and the National Formulary was not only very helpful but that the
thoroughness and completeness with which the work was done de-
serves appreciative mention—J. Am. Pharm. Assoc. 1916, v. 5,
p. 197-798.
Anon.: A book review of Hygienic, Laboratory Bulletin No. 105
calls attention to its contents as an index of pharmaceutical litera-
ture current during the period covered, and states further that the
work is particularly interesting at the present time because the
manuscripts of the Pharmacopoeia and National Formulary are
said to be about ready for the press.—Drug. Cire. 1916, v. 60, p. 291.
11. COMMITTEE OF REVISION.
Diekman, Geo. C.: Report of the Committee on Revision of the
United States Pharmacopeia.—Proc. New York Pharm. Assoc.
1916, p. 111-115.
Editorial: The U. S. P. committee of revision is composed prin-
cipally of physicians and pharmacists (retail, wholesale, and manu-
facturing), but the pharmacists are in the majority and are in con-
trol.—J. Am. M. Assoc. 1916, v. 67, p. 750.
Anon.: The National Association of Retail Druggists at its last
meeting passed a resolution to take steps to have the association
36
represented on the next U. S. P. revision committee.—N. A. R. D. J.
1916, v. 22, p. 1349.
12. NATURE AND PROGRESS OF REVISION.
Arny, H. V.: The Digest of Comments on the U. S. P. and N. F
compiled by the Hygienic Laboratory, United States Public Health
Service, furnishes all the published criticisms directed against official
preparations. These criticisms should be made the basis of a ref-
eree’s investigation, and, if no criticisms of a certain recipe have
been published, that preparation should remain just as it stood in
the old Pharmacopeia.—Pract. Drug. 1916, v. 34, No. 9, p. 25.
Whelpley, H. M.: A paper read before the Colorado Pharma-_
ceutical Association describes the method employed in revising the
U.S. P. [X.—Drug. Cire. 1916, v. 60, p. 403-405.
Remington, J. P.: A brief review of the changes of a general na-
ture which have been made in the process of revision.—Am. Drug-
gist, 1916, v. 64, No. 7, p. 23-24.
Sayre, L. E.: A paper read before the Kansas Pharmaceutical
Association discusses the difficulties experienced in bringing the
members of the revision committee to an agreement on questions
of both major and minor importance.—Drug. Cire. 1916, y. 60, p. 404.
Remington, J. P.: A discussion of the difficulties met with during
the ninth revision of the Pharmacopeeia, with special reference to
those incident to war-time conditions.—Drug. Cire. 1916, y. 60, p. 695,
Rusby, H. H.: The ninth revision of the United States Pharma-
copia has been conducted under conditions such as have not been —
realized during any previous revision, conditions as favorable as
they were exceptional.—Drug. Cire. 1916, y. 60. p. 534.
Remington, J. P.: The present method of revision, which is
unique in pharmacopeial work, will have produced a Pharmaco-
pela directly revised by a committee of probably a thousand critics
instead of the 50 members of the revision committee.—Proc. Penn-
sylvania Pharm. Assoc. 1916, p. 140.
Beringer, Geo. M.: In a discussion of the Pharmacopeeia as a
national safeguard against adulteration, it is stated that the system
of revision adopted for the U. 8. P. is distinctly American, and to
its very detnocracy must be attributed the success that has attended
the plan. It is to the honor and credit of American methods that
the work has gained the distinction of being designated as “the
autocrat of the pharmacopeeias.”—J. Am. Pharm. Assoc. 1916, v. 5,
p. 603-606.
Editorial: The revisers of the Pharmacopwia were six years in
doing work which competent and efficient men would do in six
months or a year.—Critic and Guide, 1916, v. 19, p. 362,
37
2. SCOPE.
1. NATURE AND CONTENT OF THE PHARMACOPGIA.
_ Editorial: The conservative policy adopted by the U. S. P. Revi-
sion committee is to be commended, for while the tendency of the
_times is for fewer, but better, preparations, still the fact must not be
}} overlooked that the physicians of to-day extensively employ many
}} things which the pharmacologists believe to be of little value.—
Northwestern Druggist (The), 1916, v. 17, No. 8; pide.
Cohen, S. Solis: Two extreme views were urged upon the commit-
tee of revision. One looked upon the Pharmacopeeia as a textbook
and required it to omit every drug that had not been proved by
laboratory experiments to be of therapeutic value. The other ex-
tremists desired to include everything that had ever been used as a
medicine at any time in the history of mankind by physicians, charla-
tans, or old women. As a result, the Pharmacopeeia is a happy me-
dium representing the consensus of medical and pharmaceutical
opinion.—J, Am. Pharm. Assoc. 1916, v. 5, p. 606-607.
Sayre, L. E.: One of the important suggestions as to the scope of
the Ninth Revision, as stated by the committee, is contained in the
following phrase: “Its function being to prescribe standards of
strength and purity, so that the uniform potency of medicinal agents
may be secured, therefore, it should contain the active medicinal
substances which are extensively used by physicians.”—Pharm. Era,
1916, v. 49, p. 307.
Anon.: A book like the Pharmacopeia can not be made to please
everybody, but it seems that if an error is to be made, it would be
better that the book contained too much rather than too little.
That would displease no one except the few cranks who would be
satisfied to see only some 20 most important (in their opinion) reme-
dies in it, and who little realize what medicine is for—N. A. R. D. J.
1916, v. 22, p. 939-942.
Rusby, H. H.: In a detailed review, it is stated that the scope of
the Pharmacopceia has been a subject of strong and in some ways of
bitter controversy since a period antidating by several years the
holding of the last convention. Generally speaking, this contro-
versy has keen between the medical and pharmaceutical representa-
tives, and was based upon different views as to the office and func-
tion of the book.—Drug. Cire. 1916, y. 60, p, 535.
Kraemer, Henry: The author is of the opinion that it can be
safely stated that the present U. S. P. ranks first in the pharma-
copeias of the world in the selection of official articles and in the
standards and tests that are provided.—Pharm. Era, 1916, v. 49,
p. 387,
38
Sayre, L. E.: The Pharmacopoeia is a representative and demo-
cratic book and not a bureaucratic publication, arbitrarily setting
forth the ideas of a few specialists.—Pharm. Era, 1916, v. 49, p. 307.
Anon.: A review of the U. S. P. IX. It is pointed out that the
present work contains 722 articles in the text; 277 tests and volu-
metric solutions; 315 volumetric, gravimetric, and other assays, and
62 diagnostical reagents. In the U. S. P. VIII there were 958 ar-
ticles in the text, 155 test and volumetric solutions, 149 volumetric
assays,and 35 gravimetric assays. Of the articles in the text of the
U.S. P. VIII, 243 have been dismissed, while 67 new ones have
been introduced.—Am, J. Pharm. 1916, v. 88, p. 371-3873.
Millard, E. J.: A favorable criticism and a-detailed review of the
U. 8S. P. [X.—Pharm. J. 1916, v. 97, p. 366-367, 387-388.
Editorial: The U. S. P., although one of the best in the world,
suffers from “ embarass des richesses.” A good deal of the material
which it contains is quite superfluous, and its deletion would prove
distinctly advantageous to the medical profession, to the pharma-
ceutical profession, and to the students of medicine and pharmacy.—
Critic and Guide, 1916, v. 19, p. 240.
Editorial: A review of the new edition of the U. S. P. concludes
with the statement that in the future this volume promises to be a
work embodying botanical, chemical, physical, and physiological
data, and standards pertaining to American official remedies, rather
than a book of pharmacy.—Chem. & Drug. 1916, v. 88, No. 1912,
p. 43. |
Anon.: A review of the new edition of the U. S. P. states that
among the distinctively new features of the work are the provision |
of standards for vegetable drugs; the introduction of chapters on
sterilization, on diagnostical reagents and tests, on biological assays,
and of a section giving the microscopical characteristics of powdered
drugs. Furthermore, electro-analysis has been introduced for the
first time, and the refractive indices of certain substances are given.—
Am. Druggist, 1916, v. 64, No. 8, p. 22.
Scoville, Wilbur L.: In a review of the U. S. P., it is stated that
the Ninth Revision has reinstated under the simples a list of prepara-
tions into which the particular simple enters. It is difficult to see
the value of such lists except as an excuse for more examination
questions for students, and as an extra burden for the students and
registration applicants.—Bull. Pharm. 1916, v. 30, p. 280.
Scoville, Wilbur L.: The appendix to the U. S. P. IX represents
the best and most advanced thought of the revision committee and
employs the latest established methods in chemical and physical ex-
aminations.—Bull. Pharm. 1916, v. 30, p. 279.
Cohen, S. Solis: The scientific work of the U. S, P.—botanic,
chemic, pharmaceutic, and biologic—is probably superior to any-
39
thing done in a book of this kind before-—J. Am. Pharm. Assoc.
1916, v. 5, p. 606-607.
Beringer, George M.: With each revision there has been a marked
improvement and a gradual change in the character of the work.
The Pharmacopoeia has become less and less simply a book of for-
mulas and has become more and move a book of standards prepared
with a definite purpose in view.—J. Am. Pharm. Assoc, 1916, v. 5,
p. 603-606.
Editorial: On the whole, a fair understanding and use of the
U. S. P. IX will involve a much more extended chemical and phar-
maceutical training than has any of its predecessors. We feel that
much objection to the new U.S. P. will be urged because of the high
scientific training required for its intelligent use—Midl. Drug. 1916,
y. 50, p. 349.
Schneider, Albert: The U. S. P. TX is a good piece of the book-
maker’s art. The editorial work and proof reading have been well
done; two glaring omissions, however, are noted, namely, suitable
heads for part one and part two.—Drug. Circ. 1916, v. 60, p. 692.
Asher, Phillip: One important feature that’ is lacking in the new
U.S. P. is a statement of the therapeutic properties of the substances
listed therein.—Southern Pharm. J. 1916, v. 9, p. 185.
Editorial: The U. S. P. and N. F. are insufficient as standards
and authoritative guides for the pharmacist, not only because they
give no reasons for the often peculiar working directions, not only
because the information on preservation is so meager that it is prac-
tically valueless, not only because these standards are not even found
in all pharmacies, but because they continue to recognize the mis-
chievous fluid extract to the utter absolute exclusion of the sanest
class of preparations of the vegetable materia medica, namely, the
50 per cent tincture.—N. A. R. D. J. 1916, v. 22, p. 888.
Anon.: It would be a good idea to mark each formula in the new
U. S. P. and the new N. F. in which a change has been made with
a cross or other suitable mark, so that the compounder may see at a
glance, when turning to it, that a change in formula or working
directions has been made.—N. A. R. D. J. 1916, v. 23, p. 111.
Millard, E. J.: The index to the U.S. P. LX is most complete, but
would have been improved by using a different type for articles in
part two.—Pharm. J. 1916, v. 97, p. 358.
Millard, E. J.: As the U. S. P. has always been more inclined to
recognize newer remedies than the Ph. Brit., some surprise may be
expressed at the absence of adrenalin and its solution, silver pro-
teinate, alkaline formates, iron lactate, acetylsalicylic acid, ichthyol
cr one of its substitutes, antityphoid serum, acid sodium phosphate,
and diethylbarbituric acid.—Pharm. J. 1916, v. 76, p. 366.
40
Anon.: A book review of the U. S. P. IX states that among the ©
drugs of little or no therapeutic importance or value are musk, $
arnica, eriodictyon, quassia, pumpkin seed, saw palmetto berries, —
sarsaparilla, and couch grass. Four of the nine forms of quinine are
stated to be superfluous.—J. Am. M. Assoc. 1916, v. 67, p. 764.
Holmes, E. M.: A criticism of the botanical names of the new ~
U. S. P.—Pharm. J. 1916, v. 97, p. 484-485.
Arny, H. V.: A review of the chemistry of the new Pharmaco-
peia.—Pract. Drug. 1916, v. 34, No. 9, p. 23.
Perry, E. J.: A citicism of the chemistry of the U. S. P. IX—
Chem. & Drug 1916, v. 88, p. 40.
Beringer, G. M.: A paper discussing some of the changes and
additions to the U.S. P. IX.—Am. Druggist, 1916, v 64, p. 307.
Diekman, G. C.: A paper discussing some of the changes made
in the ninth revision of the U. S. P—Pharm. Era, 1916, v. 49, p. 308.
Asher, Phillip: A review of the changes made in the ninth revision
of the U. S. P.—Southern Pharm. J. 1916, v. 9, p. 152-154, 183-185.
Beringer, George M.: A discussion of some of the changes made
in the ninth revision of the U. S. P—Pharm. Era, 1916, v. 49, p. 305.
1916, v. 34, No. 8, p. 22-94.
Anon.: A brief note calling attention to the Digest of U. 8S. P.
Changes published by the H. K. Mulford Co—aAm. J. Pharm. 1916,
v. 88, p. 432.
Diekman, G. C.: A paper discussing the new U. S. P. from the
standpoint of its pharmacy.—Pract. Drug. 1916, No. 10, p. 28.
2. THE PHARMACGPGIA AS A TEXTBOOK.
Rusby, H. H.: The appendix of the Pharmacopeia constitutes one
of the best texbooks on pharmaceutical subjects in existence. Not
only does it contain a number of tables which are indispensable for
purpose of reference, but there are explanatory chapters on various
subjects, such as thermometers, powders, percolation, etc., which can
be studied with the greatest advantage-——Drug. Cire. 1916, vy. 60,
p. 540.
Scoville, Wilbur L.: The appendix now forms, in itself, an excel-
lent texbook on methods of examination and testing for medical
and pharamceutical students, and doubtless will be so used in labora-
tories and colleges.—Bull. Pharm. 1916, v. 30, p. 279.
Raubenheimer, Otto: While the U. S. P. is not intended primarily
as a textbook, the new edition will nevertheless be used to a great
extent by students of pharmacy in acquiring their education.—D.-A.
Apoth.-Ztg. 1916, v. 37, p. 80.
Eberle, E. G.: A review of the U. S. P. IX states that part 2
should give the book a more extended use in the laboratories of
medical and pharmaceutical schools; the inclusion of explanatory
41
~ remarks, instruction in the details of manipulations, really adds
_ textbook value to the work.—J. Am. Pharm. Assoc. 1916, v. 5, p.
794-796.
Humphrey, John: A discussion of the British Pharmacopeeia in
_ its capacity as an aid to the student of pharmacy.—Pharm, J. 1916,
_y. 97, p. 835-836.
3. A LIMITED MATERIA MEDICA.
Anon.: An editorial states that the committee of revision of the
Pharmacopeeia included physicians and pharmacists, but the phar-
macists were in the majority and in control. The majority of the
representatives of the medical profession on this committee would
have preferred to see the bulk of the Pharmacopceia reduced and
its value as a work of reference enhanced by the rejection of thera-
peutically worthless drugs. The representatives of commercial in-
terests, on the other hand, argued that it was necessary for the
_Pharmacopeeia to provide standards for drugs in more or less gen-
eral use, whether worthless or otherwise——J. Am. M. Assoc. 1916,
v. 67, p. 750.
Editorial: Pharmacists should use their influence with their
physicians to hasten the day when our materia medica will be re-
stricted to a smaller number of medicaments. Physicians and phar-
macists will both profit when that day arrives——Northwestern Drug-
gist ( rhe), 1916, v. 17, No. 8, p. 23.
Wilbert, Martin I.: The immediate object of the compilation A
Handbook of Useful Drugs was to have a selected list of drugs
for use in medical schools and as a basis for examinations by State
medical examining and licensing boards. The ultimate object was
to develop a thorough knowledge regarding the uses and limita-
tions of a few drugs rather than a smattering knowledge of many.—
J. Am, M. Assoc. 1916, v. 67, p. 1491-1492.
Anon.: A book review of a volume entitled A Handbook of Useful
Drugs states that the object of this publication is to present
a materia medica that should be sufficiently extensive to include
the drugs worth while, yet not so extensive that the average prac-
titioner can not obtain a fair knowledge of them; also to continue
the movement for a restricted and more practical materia medica.—
Pract. Drug. 1916, v. 34, No. 1, p. 17.
Anon.: Prescription writing. A general discussion with a review
of useless drugs and comments on hospital mixtures—J. Am. M,
Assoc. 1916, v. 66, p. 1093-1094.
4. NOMENCLATURE.
Raubenheimer, Otto: In a review of the new edition of the U.S. P.,
_ it is stated that the nomenclature is strictly up to date; especially
is this true of the chemicals—D.-A. Apoth.-Ztg. 1916, v. 37, p. 79.
42
Editorial: Although J. B. Mcore published a plea in the Drug-
gists Circular in 1882 for the indication of the pronunciation of
titles in the U. S. P., no diacritical marks have appeared in this
work to date.—Drug. Cire. 1916, v. 60, p. 4.
Diekman, George C.: The extension of the use of synonyms, as
in the U. S. P. TX., will be welcomed by the pharmacist, and it is
believed that such extension might have been given a still wider
scope with profit—Pract. Drug. 1916, v. 34, No. 10, p. 23.
Asher, Phillip: It is not understood why synonyms have not been
included under phenyl! cinchoninic acid and a number of the other
new compounds introduced into the Pharmacopceia.—Southern
Pharm. J. 1916, v. 9, p. 185.
Holmes, E. M.: The botanical nomenclature, as followed by the
revisers of the U. S. P., ignores the generally acknowledged fact
that there are no rules without exceptions, although this fact was
recognized by Linneus, the author of the binomial nomenclature, —
when he adapted such trinomial names as Adiantum Capillus-
Veneris and Arctostaphlos Uva-Ursi.—Pharm. J. 1916, v. 97, p. 484.
Schneider, Albert: A short criticism of the terminology employed
by the U. S. P. in describing various plant tissues and tissue ele-
ments.—Drug. Cire. 1916, v. 60, p. 692-693.
Anon.: In the ninth revised edition of the U. S. P. official abbre-
viations for the Latin titles will be included. This will tend to
facilitate prescription writing and will do away with the confusion
resulting from nonuniformity in the use of abbreviations.—J. Am.
M. Assoc. 1916, v. 66, p. 1094.
Editorial: In commenting on the introduction of abbreviations
into the new edition of the U. S. P., attention is called to the fatali- -
ties resulting from a misunderstanding of the abbreviation for
barium sulphate, and the hope is expressed that prescribers will pay
more attention to this feature than they ordinarily do to suggestions
contained in the Pharmacopeeia.—Am, Druggist, 1916, v. 64, No. 8,
p. 22.
Scoville, Wilbur L.: The U. S. P. DX has taken the first step in
simplifying the nomenclature of the alkaloidal salts and has made
it quite proper to refer to “ quinine bromide,” “ emetine chloride,”
ete.—Bull. Pharm. 1916, y. 30, p. 365.
Scoville, Wilbur L.: “Aloes” and “ cantharides” are the only
plural names for drugs in the U. 8S. P. TX. Even the familiar
“cloves” is now “clove,” in keeping with most of the nomencla-
ture.—Bull. Pharm. 1916, v. 30, p. 362.
Rusby, H. H.: The fanciful name “cascara sagrada” has been
substituted as the Latin title for “ rhamnus purshiana,” which latter
is as pure Latin as the former is Spanish.—Drug. Cire. 1916, v. 60,
p- 537.
‘
45
Anon.: The term “ cubic centimeter ” is so well established and so
widely used wherever the metric system is employed that it can not
be expected that it will be universally displaced by the word “ mil.”
The latter is therefore only a superfluous synonym, and as such is
out of harmony with the simplicity of the metric system. Perhaps
it may even be taken for the abbreviation of “ millimeter,” “ milli-
gram,” or other words, derived from “ mille,” which would be
equally entitled to the same abbreviation J. Am, Med. Assoc. 1916,
v. 67, p. 764.
Anon.: An editorial pointing out the extent of the practice of in-
troducing different proprietary names for the same substance.
Special mention is made of hexamethylenamine and acetylsalicylic
acid.—Brit. M. J. 1916, v. 1, p. 532,
Fantus, Bernard: A discussion of the advisability of the use of
English in the writing of prescriptions.—J. Am. M. Assoc. 1916, v.
66, p. 1696-1699,
Fantus, Bernard: A table giving some of the official Latin names in
the Pharmacopeeia of the United States and in foreign pharmaco-
peias.—J. Am. M. Assoc. 1916, v. 66, p. 1697.
Anon.: A book review calls attention to the seventh edition of
Gould’s Pocket Medical Dictionary. It is stated that the present
edition contains 35,000 words, whereas the fourth edition dated 1900
contained definitions of only 30,000 words.—Brit. M. J. 1916, v. 1,
p. 822.
Anon.: A book review calls attention to the third edition of The
Chemists’s Dictionary of Medical Terms. The work is published by
the Chemist and Druggist of London.—Pharm. J. 1916, v. 97, p. 64.
W. P.J.: A review of a volume by A. C. Huysse on Dutch official
names and synonyms and folk names for the important drugs of
commerce.—Chem. Weekblad, 1916, v. 13, p. 135-136.
W. C. De G.: A review of Pharmaceutische gids voor chemi-
calién, drogerijen en geneesmiddelen, by P. C. De Leeuw, states
that the volume is a dictionary containing the Dutch, Latin, and
English names of the common drugs, chemicals, and medicinal prep-
arations in use in Holland.—Chem. Weekblad, 1916, y, 13, p. 772.
Pedler, Alexander: A book review calling attention to a volume
by C. M. Gupta entitled Vocabulary of Indian Medicinal Substances
and Drugs.—Analyst (The), 1916, v. 41, p. 326.
5. PUBLICITY.
Editorial: Under the operation of a resolution adopted by tha
pharmacopeeial convention requiring publicity on all proposed
changes, the new volume comes before the drug trade and the medical
profession with less of a shock than the apperance of a new edition
' has hitherto produced.—Am. Druggist, 1916, v. 64, No. 8, p. 22.
44 -
Remington. J. P.: The greatest delay in the issue of the Pharma-
copceia has been caused by the publicity given to the standards, for
although the announcement was made in the Journal of the Amer-
ican Pharmaceutical Association that there was a limit of two months >
or one month in which to send in comments and criticisms the latter
have continued to come in slowly, and this will probably continue
for two or three years—Proc. Pennsylvania Pharm. Assoc. 1916,
p. 139.
Anon.: The U. S. P. IX is out at last and will become official on
September 1; rather a short time for manufacturers, as well as re-
tailers, to set their houses in order, but sufficient, perhaps, as the
changes, deletions, and additions have been published in the drug
and medical journals——Western Druggist (The), 1916, v. 38, p. 195.
6. TIME OF PUBLICATION.
Anon.: The chairman of the revision committee is credited with
the statement that the new U. S. P. has been declared official from
September 1, 1916. and that the book will be issued early in July.—
Bull. Pharm. 1916, v. 30, p. 260.
Anon.: The Ninth Decennial Revision of the U. S. P. became official
on September 1, but so far only a limited number of copies have
been distributed. The committee of revision which fixed the date
could not have been properly advised as to conditions in the pub-
lishing world or they would not have given the trade so short a time
to get their products in line with the new standard.—Drug Topics,
1916, 92 SL 0.9, %p-0:
Editorial: The next decennial convention will meet in May, 1920,
less than four years from the date of the publication of the Ninth
Revision. Surely it will be possible to organize the work in advance
in such a way as to insure the appearance of the Tenth Revision with-
in six years of the date of the adjournment of the convention which
authorized it.—Am. Druggist, 1916, v. 64, No. 8, p. 22
Editorial: In a review of the more general changes in the new
edition of the U. S. P., it is stated that the book did not appear until
several days after it had become official—Apothecary, 1916, v. 13,
Nos Op. 15.
Anon.: It is suggested that the publication of the Ninth Revision
of the U. S. P. be delayed until 1920, and that the volume then be
known as the [X—X revision. This would give the pharmacopeial
revision committee a chance to catch up and remain up to date. It
would also save millions of dollars for the drug and pharmaceutical
trade.—National Drug Clerk, 1916, v. 4, p. 116-117,
45
Editorial: The date set for the publication of the Pharmacopeia
has been changed so often that some time will be necessary to acquaint
_ the pharmacists of the United ‘States with the fact that the work is
- now ready for distribution.—Pract. Drug. 1916, v. 84, No. 4, p. 18.
. 7. DOSES.
Rusby, H. H.: The doses of the new U. S. P. remain the average
doses as heretofore, the committee having very wisely refused to
assume responsibility for stating what is the maximum dose and hav-
ing taken great pains to indicate in the preface that they disclaimed
such responsibility.—Drug. Cire. 1916, v. 60, p. 538.
Sayre, L. E.: If the revision committee should have been instructed
to insert in the appendix a table of maximum single doses of the
toxic and most potent of the official drugs, it would have served a
double purpose. It would have been a valuable text for instructors
in medical colleges and would have been a protection to the dispenser
and administrator of medicines, warning them that beyond such a
dose there would be a great risk —Pharm. Era, 1916, v. 49, p. 356.
8. ANTIDOTES.
Beach, Samuel C.: General and specific descriptions of procedures
for the emergency treatment of poisoning—Am. J. Clin. Med. 1916,
vy. 23, p. 837-340, 429-431, 504-506.
Anon.: An article credits the Eclectic Medical Journal with point-
ing out the value of boiled starch as an antidote for iodine poison-
ing.— Nat. Druggist, 1916, v. 46, p. 18.
Fantus, Bernard: An experimental study of antidotes in mercuric
chloride poisoning.—J. Lab. & Clin. Med. 1916, v. 1, p. 879-894.
_ <Anon.: In a reference to the use of calcium sulphide as an antidote
for mercuric chloride poisoning, it is stated that J. H. Wilkins, of
Cincinnati, Ohio, was able to save the lives of animals when treat-
ment was begun as late as 48 hours after the poison had been adminis-
tered.—Canadian Pharm. J. 1916, v. 29, p. 436.
Anon.: A discussion on the value of sodium sulphate as an antidote
for phenol (carbolic acid) poisoning.—J. Am. M. Assoc. 1916, v. 67,
“p. 535.
_ Anon.: Before a gathering of doctors at Colombo, Ceylon, Mr.
Donald Obeysekere apparently demonstrated the efficacy of plan-
tain juice as an antidote of the bite of the cobra—Mulford’s Vet.
Bull. 1916, v. 8, p. 34.
9. WEIGHTS AND MEASURES.
Editorial: The use of the metric system alone in the manufacture
of pharmaceutical preparations is urged upon all pharmacists, us
the forthcoming N. F. will give its formulas in this system.—A pothe-
seary, 1916, v. 13, No. 7, p. 13.
46
Editorial: The term “ mil” was first used by the Pharmaceutical
Society of Great Britain about a dozen years ago, when that socie
took action to have the word adopted.—Drug. Circ. 1916, v. 60, p. 391
Diekman, George C.: One of the reasons for the introduction o
the term “mil” into the U. S. P. is that the United States Bureau
of Standards declared the words “ cubic centimeter ” and its abbrevia
tion cc. to be a misnomer. Another reason is that there is a sligh
difference between the cubic centimeter and mil. Still another 1
that the words “ cubic centimeter ” destroy the harmony of the metric
terms. To many none of the reasons seem sufficient to warrant so
radical a change.—Pract. Drug. 1916, v. 34, No. 10, p. 23.
Editorial: We have actively opposed the introduction of the word
“mil,” although logically correct, for the reason that all of the
literature of chemistry for the past century is based upon the use
of the term “ cubic centimeter,” and the purely theoretical considera-
tions in favor of the former appear to outweigh the practical objec-
tions to its introduction.—Am. Druggist, 1916, v. 64, No. 8, p. 22.
Anon.: The term “cubic centimeter” is so well established and
so widely used, wherever the metric system is employed, that it
can not be expected that it will be universally displaced by the
word “mil.” The latter is therefore only a superfluous synonym,
and as such is out of harmony with the simplicity of the metric
system. Perhaps it may even be taken for the abbreviation of
“ millimeter,” “milligram,” or other words derived from “ mille,”
which would be equally entitled to the same abbreviation—J. Am.
M. Assoc. 1916, v. 67, p. 764. é
Editorial: The expression “mil” is not only useless but it may
lead to confusion. Particularly are we afraid that it may be taken
for an abbreviation of milligram.—Critie and Guide, 1916, y. 19,
p. 365. ;
Schneider, Albert: The universally recognized unit for making
microscopic measurements is the 0.001 part of a millimeter, desig-
_ nated as “micron” and indicated by the Greek letter » (mu). In
the U. S. P., the millimeter is given as the micrometric unit and the
measurements are given in millimeters and fractions thereof. No
explanation is offered showing why this unit was adopted in pref-
erence to the micron.—Drug Cire. 1916, v. 60, p. 692.
Anon.: The omission of the apothecaries’ quantities from the
formulas of the new N. F. is likely to meet some adverse criticism.
Changes in habit come slowly. The method employed in the N. F. |
III was of course a mistake, for the reason that the metrie and
apothecaries formulas there given were not equivalent, and con-
fusion resulted.—N. A. R. D. J. 1916, v. 22, p. 939.
Watson, Charles N.: An article dealing with the origin of Eng-
lish measures of length.—Nature, 1916, v. 96, p. 69-72.
47
« Dietel, Herman: A discussion of the Harrison law with respect
to its effect on the adoption of the metric system.—Rocky Mountain
is (The), Denver, 1916, v. 30, No. 9, p. 22-26.
_ Anon: Consul Ss E. D. W inslow, at Copenhagen, Denmarts,
o reports that, beginning April 1, 1916, the metric system became of-
é ficial in Denmark.—Northwestern Druggist (The), 1916, v. 17, No.
6, p. 34.
England, J. W.: A short discourse on how to use the metric sys-
tem.—J. Am, Pharm. Assoc. 1916, v. 5, p. 723-726; see also Apothe-
cary, 1916, v. 13, No. 7, p. 15-16.
Heller, Charles T.: A short paper explaining how to convert
metric into apothecaries’ measures.—Northwestern Druggist (The),
1916, v. 17, No. 2, p. 42.
O’Connor, D. Chas. : Exercises in the use of the metric system
for the pharm i , Vv. 23, p. 5(-61.
Andrews, H. M.: Rules for converting the eee dose into the
corresponding metric one.—Pharm. J. 1916, v. 96, p. 182.
Doerschuk, A. N.: A discussion of the advantages and disadvan-
tages of the metric system in prescribing.—Proc. Missouri Pharm.
Assoc. 1916, p. 89-92.
Rae, W. N., and Reilly, J.: An essay dealing with precision in
chemical weighing in a very complete and systematic manner.—
Chem. News, 1916, v. 114, p. 187-189, 200-203.
Stratton, S. W.: Specifications and tolerances for weights and
measures and weighing and measuring devices.—Cire. Bur. Stand.
1916, No. 61, p. 1-44.
Anon.: A reprint of Wisconsin tolerances and specifications for
glass graduates prescribed by George J. Weigle, ex officio State
Superintendent of Weights and Measures.—National Drug Clerk,
1916, v. 4, p. 554.
Anon.: Inspector Cohn, of the Indiana State Board of Health, re-
ports that only 441 of 871 balances inspected were in good order, 340
were in fair condition, and 90 were condemned. Out of 10,921
weights tested, 659 were accurate, 6,335 were hght, 1,990 were heavy,
and 1,828 were condemned because they were either too light or too
heavy to be longer used.—Pharm. Era, 1916, v. 49, p. 222.
Anon.: John F. Farrell, superintendent of weights and measures
of New York State, reports that many of the weights used by drug-
gists are of the variety known as “ coin weights,” being in the shape
of the nickel five-cent piece. These weights take up a great amount
of dirt and are not of the type which should be used. They are,
therefore, being condemned wherever found.—Oil, Paint & Drug
Rep. 1916, v. 90, No. 22, p. 57.
Weigle, George J.: The inspection of weights and measures in
Wisconsin during the year 1915 showed that 34.2 per cent of the pre-
48
scription weights and 26.3 per cent of the glass graduates examined ©
were inaccurate——Proc. Wisconsin Pharm. Assoc. 1916, p. 63-65.
Anon.: The National Association of Retail Druggists at its last
convention passed a resolution recommending the adoption by the
United States Government of a method that will prevent the inter-
state shipment of measuring and weighing devices that do not meet
the requirements of the United States Bureau of Standards.—N. A.
R. D. J. 1916, v. 22, p. 1352. 4
Donald, R.: Supplemental notes on a method of drop-measuring
liquids and suspensions.—Lancet, 1916, v. 191, p. 423-429.
10. OBJECTS AND USES.
Lascoff, J. Leon: The Pharmacopeia is a book of standards for
such substances as are sufficiently used as remedial agents to warrant
recognition and the fixing of proper standards. It is not consid-
ered as an authority on therapeutics, and the admission or deletion
of any article is not to be considered as an indication of its thera-
peutic value.—Pract. Drug. 1916, v. 34, No. 1, p. 24.
Editorial: To the retail pharmacist, the U. S. P. IX is without
question the most complete and valuable Pharmacopceia that has ever
been issued. Every pharmacist should have a copy of this book, for
it contains more condensed facts and valuable information than any
of the various textbooks, although the latter are essential for ex-
tended articles on specific subjects—Northwestern Druggist (The),
1916, No. 8, p. 24.
Editorial: The force of the argument that the Pharmacopeeia is
necessary as a standard for drugs is somewhat impaired by the fact
that the National Formulary, which has also been made a book of
legal standards, now includes individual drugs as well as combina-
tions; the new edition of the Formulary, in fact, contains a large
number of drugs which were dropped from the U. 8S. P. VIII—
J. Am. M. Assoc. 1916, v. 67, p. 750-751.
Sigel, Irving S.: I have been employed in drug stores where the
U.S. P. and N. F. were as rare as a team of horses on an elevated
road. The proprietors of these stores kept secret formulary books
which were captioned “M. O. P.,” meaning “My own pharmaco-
poia.”—National Drug Clerk, 1917, v. 5, p. 168.
Beringer, G. M.: A paper discussing the Pharmacopeeia in the
light of its acting as a safeguard against adulteration.—J. Am.
Pharm. Assoc. 1916, v. 5, p. 603.
Arny, H. V.: A paper discussing the relation of the U. S. P. IX
to the newer pharmacy, points out that the book will be of use only
to such pharmacists who are trained to perform high-grade chemical
and microscopical work.—J. Am. Pharm. Assoc. 1916, v. 5, p. 989.
49
_ Kilmer, F. B.: A paper calling attention to the possibility of drug-
gists selling copies of the Pharmacopeia to physicians, hospitals,
libraries, municipal laboratories, etc.—Pract. Drug. 1916, No. 8, p. 24.
oe 11. ADDITIONS AND DELETIONS.
4
s Anon.: A book review of the new edition of the U.S. P. states
that the work contains 1,436 articles as compared with a total of 1,147
in the Eighth Revision. Two hundred and forty-three articles
formerly official have been dismissed and 67 new articles have been
introduced. A list of the articles added is appended.—Am. Druggist,
1916, v. 64, No. 8, p. 22.
_ Sayre, L. E.: A discussion: pointing out the difficulties experienced
by the subcommittee on scope, with respect to additions and dele-
tions.—Pharm. Era, 1916, v. 49, p. 306, 355.
Rusby, H. H.: A very important addition to the text of the U. S.
P., now made for the first time, is the introduction of official abbrevia-
tions of the titles. Its adoption at the present time is undoubtedly
one of the indirect results of the food and drug statute——Drug. Cire.
1916, v. 60, p. 537.
Editorial: The most striking general addition to the Pharmacopceia
is that of official abbreviations. They will relieve the pharmacist of
much responsibility in this respect providing he does not misinterpret
them.—A pothecary, 1916, v. 13, No. 9, p. 15.
Anon.: The principle of making use the sole criterion for admis-
sion to the Pharmacopeeia has not been strictly observed. Good
results from the efforts of the medical contingent are to be observed
here and there, as in the deletion of elixir of the phosphates of iron,
quinine, and strychnine, and of the emulsion of cod liver oil with
hypophosphites.—J. Am. M. Assoc. 1916, v. 67, p. 751.
Scoville, Wilbur L.: A significant fact about the 67 additions to the
U. S. P. IX is that approximately a quarter of their number pertain
to hypodermic medication.—Bull. Pharm. 1916, v. 30, p. 365.
Beringer, George M.: The preparations added in the revision of
‘the Pharmacopceia have not been very numerous, the tendency being
to leave to the National Formulary the providing of formulas for
preparations—Am. Druggist, 1916, v. 64, No. 8, p. 24.
Raubenheimer, Otto: In an enumeration of the 15 new galenicals
added to the U. S. P., the author states that the addition is highly
commendable from a pharmaceutical point of view. Hope is also
expressed to the effect that physicians will frequently prescribe them,
since the subcommittee on scope, which is responsible for these
additions, consists principally of the medical profession—J. Am.
Pharm. Assoc. 1916, v. 5, p, 1835-1339,
-110095°—19——4
30
Scoville, Wilbur L.: In the U. S. P. UX, under the simples, a li
of preparations into which the particular simple enters is agai
given. It is difficult to see the value of such lists except as an excu
for more examination questions for students and registration appli-
cants.—Bull. Pharm. 1916, v. 30, p: 280.
Rusby, H. H.: In some cases deletions have been made for the sol
purpose of dodging difficult questions, the very ones for which phar-
macopeeias are chiefly needed. The deletion of whisky and brandy
and of viburnum opulus are examples of this kind.— Drug. Cire. 1916,
v. 60, p. 536.
12. PURITY AND STRENGTH.
Diekman, George C.: The purity rubric was introduced into the
U.S. P. VIII and has been retained in the U.S. P. 1X. The figures
given in the U. S. P. IX represent requirements that can be reason-
ably demanded and met in each instance.—Pract. Drug. 1916, v. 34,
No. 10, p. 28.
Kraemer, Henry: The purity rubric, which was introduced i in the
U. S. P. VIII in connection with the definitions of chemical sub-
stances, was extended in the Ninth Revision to vegetable and animal
drugs. That this rubric is essential will be apparent to anyone who
is familiar with the quality of drugs as seen in commerce. It is a
very great step forward and will restore the lost art of the garbling
of drugs by pharmacists and direct greater attention to their quality
and purity.—Pharm. Era, 1916, v. 49, p. 387.
Scoville, Wilbur L.: The purity rubric is now a maximum mini-
mum affair. The real standard is the mean between the two and
this will doubtless be honored in all cases.—Bull. Pharm. 1916, v. 30,
p. 280.
Scoville, Wilbur L.: A “ purity rubric” adopted for most of the
vegetable drugs in the Pharmacopeeia is a statement which limits the
amount of stems and “other foreign matter” which can be ali¥ved,
and also places a limit on the yield of ash—Bull. Pharm. 1916, v. 30,
p. 362-363.
Scoville, Wilbur L.: Since the new Pharmacopeeia states maximum -
as well as minimum strengths, the fact that a preparation is stronger —
than that officially recognized does not mean that it conforms to the
law. It must be within the limits established by the U. S. P. or it is
liable to seizure for being adulterated and the owner is liable to a
fine.-—Bull. Pharm. 1916, v. 30, p. 322.
Beringer, George M.: The principle of allowing for the proper
variability of chemicals and for the natural variation in erude drugs
has led to many modifications of the rubric requirements by which,
instead of the fixed purity statements of the previous Revision, there
now appears in most of the monographs a variability allowance in—
51
accordance with determined conditions, and the limitations of such
-yariability are officially defined—aAm. Druggist, 1916, v. 64, No. 8,
‘p. 23.
_ Anon.: One of the principal features of the U. S. P. IX is the in-
troduction of definite limits of purity, in place of the old “about”
or “not less than.” This will be a big help to manufacturers and
dealers who have been more or less harassed in the past by officials
ot meticulous minds, who made no allowance for experimental or
personal error in reporting results——Drug Topics, 1916, No. 9, p. 8.
Beringer, George M.: The changes that have been made in the
strength of the chemical products of the U. S. P. are, for the most
_part, such as were required by the commercial conditions and the
quality of the products commonly dispensed as medicines.—Am.
Druggist, 1916, v. 64, No. 8, p. 23.
Hilton, S. L.: The alcoholic strength of many of the N. F. prepa-
rations has been reduced for the purpose of eliminating the possi-
bility of their being used as beverages.—Bull. Pharm. 1916, v. 30, p.
281.
Hilton, 8. L.: The narcotic drug content of a number of the N. F.
preparations has been reduced in order to comply with the excep-
tions of section 6 of the Harrison law.—Bull. Pharm. 1916, v. 30, p.
281.
Anon.: In a discussion of standards for purity and strength, it is
urged that the official standard names only should be used in con-
nection with official standard products, and that below-standard and
above-standaid preparations should be recognized under other names
and designations.—N. A. R. D. J. 1916, v. 22, p. 670-671.
Sayre, L. E.: An enumeration of the new standards of the U. S. P.
IX.—Am. Food J. 1916, v. 11, p. 456-457.
Beringer, George M.: A detailed discussion of what the new U.
S. P. standards for whisky and brandy should be.—Am. J. Pharm.
1916, v. 88, p. 49-65.
Anon.: The National Association of Retail Druggists at their last
convention passed a resolution favoring an official standard for
whisky and brandy in order that inferior articles for medicinal pur-
_ poses may be avoided.—N. A. R. D. J. 1916, v. 22, p, 1851
13. ATOMIC WEIGHTS.
Scoville, Wilbur L.: The atomic weights of the U. S. P. are now
based upon oxygen=16 instead of hydrogen=1, which eliminates
many of the fractions in calculations, and brings the work into har-
mony with chemical usage throughout the world.—Bull. Pharm.
1916, v. 80, p. 279.
Clark, F. W.: Annual report of the International Committee on
Atomic Weights, 1917.—J. Am. Chem. Soc. 1916, v. 38, p. 2219-2221,
52
Baxter, Gregory P.: Twenty-third annual report of the Committee
on Atomic Weights. Determinations published during 1915.—J. Am.
Chem. Soc. 1916, v. 38, p. 489-496. |
Anon.: A table of international atomic weights for 1916 reprinted
from the Annual Report of the International Committee on Atomic
Weights.—Drug. Circ. 1916, v. 60, p. 11.
Guye, Ph. A.: A criticism of the International Atomic Weights
Committee for its apparent lack of complete and definite methods for
revising atomic weights. Criteria for justifying atomic weight
changes are also suggested—J. chim. phys. 1916, v. 14, p. 449-461.
Editorial: The new table of atomic weights recently published by —
the International Committee on Atomic Weights necessitates a com-_
plete revision of the figures and factors which are to be used in the
new Pharmacopeia.—Pacific Pharm. 1916, v. 9, p. 257.
Fajans, K., and Lemberg, M.: A description of a method for re- —
lative atomic weight determination—Chem. Zentralbl. 1916, v. 2, p.
214.
Bilecki, A.: An article describing a fundamental unit to be used in
the building up of the atomic weights of the elements. The unit is
given as 0.307692307.—Ztschr. anorg. Chem. 1916, v. 98, p. 86-96.
Hardin, W. L.: An address outlining the historical development of
the present ideas of the structure of the atom, with references to the
original works.—Science, 1916, v. 44, p. 655-664.
Clay, J.: A review dealing with the structure of the atom.—Chem.
Weekblad, 1916, v. 13, p. 1078-1103.
van der Brock, A.: A note on the relation of atomic weights to
radioactive constants.—Nature, 1916, v. 96, p. 677.
Moles, E.: The new values of the atomic weights of carbon and sul-
phur as announced by the International Committee on Atomic
Weights are stated to be founded upon an error of calculation.—J.
chim. phys. 1916, v. 15, p. 51-59; see also P. A. Guye, ibid., p: 60-63.
de Coninck, Oechsner, and Gérard: From determinations using the
chloride, the atomic weight of bismuth was found to be 208.5.—
Compt. rend. Acad. sc. 1916, v. 162, p. 252.
3. NONPHARMACOP@IAL STANDARDS.
1. NATIONAL FORMULARY.
Anon.: The Committee on Publication of the American Pharma-
ceutical Association makes the announcement that the National
Formularly, fourth edition, will be ready for distribution about
July 1, 1916.—Western Druggist (The), 1916, v. 38, p. 136.
Cook, E. F.: A brief history of the fourth edition of the N. F.,
with a detailed discussion of the preparations contained therein.—
Drug. Cire. 1916, v. 60, p. 541.
ee ee ee ee ee
53
¥ Hilton, S. L.: A general review of some of the changes made in
e National Formulary.—Bull. Pharm. 1916, v. 30, p. 280-281.
Anon.: A review of the fourth edition of the National Formulary
Be atec that 183 formulas have been dropped and 201 have been added,
)) making a total of 601 titles in Part 1. Of these, 589 are formulas.
Part 2 contains 188 articles, most of which were contained in former
editions of the U. S. P.—Am. Druggist, 1916, v. 64, No. 8, p. 21.
") Scoville, Wilbur L.: This is the first issue of the National Formu-
) lary to state exact standards or to require assays, and some pharma-
cists may be slow to realize that new legal standards are established
by it—Bull. Pharm. 1916, v. 30, p. 324.
_ Anon.: A book review states that despite its long and honorable
history and useful career, the National Formulary is not as gener-
ally familiar to the members of the medical profession as it should
1) be. To many of them it is but a name and is thought of as a mere
») collection of formulas for skin lotions, shoe blacking, and imitation
' proprietaries of interest only to druggists—Am. J. Clin. Med. 1916,
‘y. 23, p. 961.
Editorial: The National Formulary shows, perhaps, the most
radical changes over its predecessor in bringing its nomenclature,
formulas, and descriptions into agreement with the general style and
method of the Pharmacopeeia.—A pothecary, 1916, v. 18, No. 9, p. 15.
Scoville, Wilbur L.: In a review of the N. F., IV, the author states
that the Pharmacopeia is controlled by the “regular” school of
medicine, but that the National Formulary makes no distinction
between allopaths, homeopaths, osteopaths, chiropractors, or any
other school of practice. Its mission is to perfect or select the
pharmaceutical qualities of the formulas, and to allow the physi-
cians as a whole to adjust or judge the therapeutics.—J. Am. Pharm.
Assoc. 1916, v. 5, p. 804-807.
. Editorial: In a discussion of the therapeutics of the N. F., IV, it
is stated that the volume does not meet the approval of the American
Medical Association.—J. Am. M. Assoc. 1916, v. 67, p. 764.
Scoville, Wilbur L.: A review of the changes in the N. F., I1V.—
Western Druggist (The), 1916, v. 38, p. 231-232.
Apple, F. N.: It is recommended that an epitome of the National
Formularly be prepared and distributed among pharmacists and
physicians in order to increase the sale of the book.—J. Am. Pharm.
Assoc. 1916, v. 5, p. 1226.
2. RECIPE BOOK.
Wilbert, M. I.: A paper dealing with the history, scope, and possi-
bilities of the recipe book of the American Pharmaceutical Asso-
ciation, A bibliography of the recipes published in the Journal of
54
the A. Ph. A. from 1912 to date is given—J. Am. Pharm. Assoc.
1916, v. 5, p. 1121.
Anon.: A symposium of comments on the nature and scope of
the recipe book—J. Am. Pharm. Assoc. 1916, v. 5, p. 1213-1216.
Raubenheimer, Otto: The author announces the receipt of a book -
entitled Sammlung von Vorschriften fiir Zubereitungen zum Ersatz
von Specialitaten des Feindlichen Auslandes and points out its pos-
sible value in the compilation of formulas for the A. Ph. A. Recipe
Book.—Pacific Pharm. 1916, v. 9, p. 270-271.
Anon.: A list of formulas proposed for the A. Ph. A. recipe —
book.—J. Am. Pharm. Assoc. 1916, v. 5, p. 309-810, 422425, 529-582,
631-634, 748-751, 862-865, 991-994, 1126-1129, 1265-1268, and 1397—
1400.
Anon.: A list of a number of formulas proposed for the A. Ph. A.
recipe book.—Bull. Pharm. 1916, v. 30, p. 255.
Anon.: A compilation of formulas for preparing a variety of arti-
cles, both medicinal and nonmedicinal.—Canadian Pharm. J. 1916, —
v. 49, p. 36, 76, 116, 141, 232, 280, 328, 424; v. 50, p. 34, 74, 154, 202.
Anon.: A list of popular formulas for a variety of preparations.—
Am. Druggist, 1916, v. 64, No. 12, p. 28-29, 32, 37-88.
Porterfield, W. P.: A number of formulas for masking the disagree-
able taste of certain substances, for suspending solids in liquids, ete.—
Proc. North Dakota Pharm. Assoc. 1915, p. 51-58.
Groat, H. S.: A presentation of a number of formulas for the
manufacture of toilet preparations, including casein creams, cold
creams and toilet lotions—J. Am. Pharm. Assoc. 1916, v. 5, p.
150-156.
Reimers, M. N.: Formulas for the preparation of “ Pulvis fluens
Hydrargyri” and other mixtures are presented.—Apoth.-Ztg. 1916,
Wirol, p.. 16.
3. NEW AND NONOFFICIAL REMEDIES.
Anon.: The rules of the council on pharmacy and chemistry of the
American Medical Association for admission to Vew and Nonoffcial
Remedies require that the composition of a remedy be nonsecret, that
its uniformity be safeguarded, that no false claims be made regarding
its therapeutic properties, and that its use shall be based on at least a
probability of therapeutic merit.—J. Am. M. Assoc. 1916, v. 66,
p. 918.
Anon.: A list of new remedies accepted by the council on phar-
macy and chemistry of the American Medical Association for admis-
sion to Vew and Nonofficial Remedies.—Cleveland M. J. 1916, p. 135—
199, 291, 365, 427, 497, 537, 620, 678, 737, 814.
Anon.: A book review of Vew and Nonofficial Remedies states that
the volume is primarily intended for the physician, but that no
ee ee ee ee ee ee ene
eh ebtneciene
a ee ee ae
55
i:
EA pharmacist who wishes trustworthy information relating to the newer
remedies, proprietary or nonproprietary, should be without it.—
Pharm. Era, 1916, v. 49, p. 211.
‘3 Anon.: A review of New and Nonofficial Remedies, 1916, states
that the book is a sort of dispensatory of new and Gnade reme-
| dies, and as such will be found of great service to pharmacists as well
as physicians.—Drug. Circ. 1916, ve 60, p. 291.
Thum, Jehn K.: A book review of New and Nonojficial Remedies
_ published by the American Medical Association. Special mention is
made of the chapters on digitalis- principles, arsenic compounds,
‘serums, and vaccines, and digestive ferments.—Am. J. Pharm. 1916,
We 88, p- PA
‘ SYNTHETICS.
_ Anon.: A list of new synthetic remedies, with descriptions of the
methods by which they may be prepared, their properties, etc.—Bull.
“se. pharmacol. 1916, v. 23, p. 47-49.
_ Marotta, Domencio: On the methods of preparation and proper-
ties of a number of the new synthetic remedies.—Boll.. chim-farm.
1916, v. 55, p. 65-69, 97-104.
Schrauth, W.: A discussion of the use of fats in the preparation of
synthetic remedies.—Seifensieder Ztg. 1916, v. 86, p. 217-221 through
Chem. Abstr. 1916, v. 102, p. 1905.
Childs, W. H.: The coal-tar products family tree and some of its
branches.—Oil, Paint & Drug Rep. 1916, v. 90, p. 40-41; see also
Chem. Abstr. 1916, v. 10, p. 2140.
Carr, Francis ee ee aspects of the future of the erent
chemical industry of Great Britain—Pharm. J. 1916, v 97, p. 275-
276.
NEW REMEDIES.
Arny, H. V.: A copy of the report of the Committee on New Reme-
dies of the New York Pharmaceutical Association, consisting prin-
cipally of a list of such preparations—Proc. New York Pharm.
Assoc, 1916, p. 211-245.
Anon.: A list of new remedies with proprietary names is given.—
"Am. Druggist, 1916, v. 64, No. 1, p. 27-28; No. 2, p. 31-32; No. 3.
“p. 81-82; No. 4, p. 32, 37; No. 6, p. 29-30; No. 7, p. 81; No. 8, p.
37; No. 10, p. 830-31; No 12, p. 32.
Anon.: A list of recently introduced new remedies, with a de-
scription of their nature and composition.—Siidd. Apoth.-Ztg. 1916,
v. 56, p. 18, 36, 54-55.
Rabow, S.: A review of the therapeutic novelties made known in
1915, including the specialties and proprietary remedies.—Chem. Ztg.
1916, v. 40, p. 145-147, 167-169, 1838-185; see also Chem. Abstr. 1916,
y. 10, p. 12538.
56
Mentzel, H.: Notes on the composition of a number of new reme- |
dies aaieoeaced during the years 1915 and 1916.—Pharm. Zentralh.
1916, v. 57, p. 5-7, 54-55, 70, 92, 112, 182, 154, 170.
Anon.: On ene composition con properties of a number of new
proprietary remedies.—Apoth.-Ztg. 1916, v. 31, p. 15, 34, 42, 56, 67,
68, 79, 95, 115.
Tecterbahia: Data relating to the composition and properties of
a number of recently introduced remedies.—Chem. Zentralbl]. 1916,
v. 87, part 2, p. 417-418 from Pharm.-Ztg. 1916, v. 61, p. 246, 286,
293, 318, 379, 404, 419, 440, 450.
Anon.: A fe iptive ee of new remedies of recent manufacture.—
Pharm. Weekblad, 1916, v. 53, p. 165-172, 221-228, 457-460, 1241—
1248, 1641-1644, 1701-1704.
Messner, J.: A quarterly report on new remedies. A review of
the literature with a biography.—Ztschr. angew. Chem, 1916, v. 29,
p- 257-261, 819-823, 401-402, 408-409; see also C. Mannich, p.
285-288.
Klein, Friedrich: On colloids, their significance i in pharmacy and
medicine.—D.-A. Apoth.-Ztg. 1916, v. 87, 57-58, 74~75.
Anon.: A book review calls cowie to a volume by C. Bachem
on German substitutes for foreign pharmaceutical specialties—
Chem.-Ztg. 1916, v. 10, p. 611.
PATENTS AND TRADE-MARKS.
Stewart, F. E.: Report of the A. Ph. A. Commitee on Patents and
Trade-Marks.—J. Am. Pharm. Assoc. 1916, v. 5, 1232-1237.
Anon.: Owing to the scarcity and high price of drugs and dyes —
and the impossibility of replenishing our supplies of some of them
from abroad, it is high time that our patent laws were amended.—
Drug. Circ. 1916, v. 60, p. 324.
Anon.: The National Association of Manufacturers of Medicinal
Products at its annual meeting passed a resolution to the effect that
the association is opposed to any amendment of the patent, trade-
mark, and copyright laws of the United States of America that shall —
directly or indirectly effect discrimination against inventions and
discoveries in chemistry, pharmacy, medicine, or surgery.—Pharm.
Era, 1916, v. 49, p. 122.
Stewart, F. E.: Patents and trade-marks discussed with respect to
the Goldwater ordinance of New York.—Proc. Pennsylvania Pharm.
Assoc, 1916, p. 88-91.
Anon.: An editorial discussing the perpetuation of patents by
trade names, with special reference to aspirin—J. Am. M. Assoc.
1916, v. 67, p. 515-516.
57
_ Anon.: Tlustrated descriptions of new patents and trade-marks
_ of pharmaceutical interest.—Spatula (The), 1916, v. 22 and 23.
Jessop, Earl N.: A classified German patent bibliography.—
_ J. Ind. & Eng, Chem. 1916, v. 8, p. 1053-1054.
_Anon.: Announcement is made that section 27 of the British
_ patents and designs act of 1907 has been suspended during the con-
_ tinuance of the war and for six months thereafter by an act of
Parliament dated November 23, 1915. The section referred to allows
the revocation of any patent not worked in the United Kingdom
within four years after date of granting—Com. Rep. 1916, No. 5,
p. 65.
_ Anon.: A discussion of proposed changes in French laws gov-
erning patents and trade-marks as they apply to the chemical and
pharmaceutical industries—Bull. Assoc. Gén. Syn. Pharm. France,
1916, v. 19, p. 33-37.
Anon.: An order in council has been adopted by the Federal Gov-
ernment of Australia canceling all German trade names and trade-
marks.—Canadian Pharm. J. 1916, v. 49, p. 220.
For Swiss patents and trade-marks see Schweiz. Apoth-Ztg.
1916, v. 54.
CHEMOTHERAPY.
Stone, William S.: A review of the history of chemotherapy in
the treatment of cancer.—Med. Rec. 1916, v. 90, p. 628-634.
Walker, Chas. H., and Klein, Frederick: A discussion of the
therapeutic value of selenium with special reference to the treatment
of cancer.—Pract. Drug. 1916, v. 34, No. 1, p. 41-48.
De Witt, Lydia M.: An article setting forth the present status of
chemotherapy in tuberculosis—J. Lab. & Clin. Med. 1916, v. 1,
p. 677-684.
Koga, Gensaburo: A contribution to the chemotherapy of tuber-
culosis—J. Exper. M, 1916, v. 24, p. 107-185; see also Morisuke
Otani, p. 187-206.
Anon.: An editorial discussing some of the late developments in
the chemotherapeutic treatment of tuberculosis—J. Am. M. Assoc.
1916, v. 67, p, 448.
~ De Witt, Lydia M., and Sherman, Hope: Researches relative to
the biochemistry and chemotherapy of tuberculosis with special ref-
erence to the bactericidal action of copper salts.—J. Infec. Dis. 1916,
v. 18, p. 368-382.
McDonagh, J. E. R.: The rationale of chemotherapy in syphilis,
with a description of some new drugs prepared with the knowledge
gained therefrom.—Lancet, 1916, v. 190, p. 236-239.
58
RADIOACTIVITY.
Aubry, A.: A review of the recent progress in radiochemistry and
radiotherapy.—J. pharm. et chim. 1916, v. 18, p. 280-289.
Loomis, Albert G., and Schlundt, Herman: A report of some ex-
periments on the pac omeien of SE tne in carnotite ores.—J. Ind.
& Eng. Chem. 1916, v. 8, p. 990-996.
Schlundt, Herman: Some experiments on the extraction of radium
from carnotite ore with concentrated sulphuric acid.—J. Phys. Chem.
1916, v. 20, p. 485-494.
Furber, F. B.: An outline of the methods used in the Bureau of
Chemistry for determining the radioactivity of such miscellaneous
materials as bottled mineral waters and therapeutic preparations.—
J. Assoc. Off. Agric. Chem. 1916, v. 2, part 1, p. 116-119.
W. P. J.: A book review of a volume by Frederick Soddy entitled
The Chemistry of the Radio Elements—Chem. Weekblad, 1916,
v. 13, p. 1106.
W. P. J.: In a review of a volume by Albert Laborde entitled
Methods de mesure employees en radioactivité, it is stated that,
although not complete, the book gives a good survey of the numerous
methods employed in the measurement of dio —Chem.
Weekblad, 1916, v. 18, p. 1107. |
ee Wm. S.: Some physical facts about the radioactive
elements as applied in medicine.—Therap. Gaz. 1916, v. 40, p. 87-90.
Danne, Jacques: Radium emanation, its production and medical
properties.—Bull. sc. pharmacol. 1916, v. 23, p. 19-83.
Brown, J. MacDonald: A discussion of radium and its use in
therapy.—Pharm. J. 1916, v. 96, p. 217-218, 269-271, 295-297.
Aubry, A.: A short article dealing with radium and its therapeu-
tic uses.—Farm. Espan. 1916, v. 48, p. 453-457.
Chase, Walter B.: A Bien of some clinical aspects of radio-
therapy.—Med. Rec. 1916, v. 90, p. 410-414. .
Field, C. E.: The physio-chemical properties of radium considered
with relation to high blood pressure—Med. Rec. 1916, v. 89, p.
136-139.
Cole, H. M.: A short article dealing with the use of radium in
dermatology.—Cleveland M. J. 1916, v. 15, p. 645-651.
Abbe, Robert: Clinical data showing the efficiency of radium in
nonmalignant surgical conditions.—Med. Ree. 1916, v. 90, p. 47-50.
Sutton, Richard L.: An account of the use of radium in the treat-
ment of synovial lesions of the skin—J. Am. M. Assoc. 1916, v. 66,
p 565-566.
Simpson, Frank E.: A report on the use of radium in the treat-
ment of cancer and various other diseases of the skin.—J. Am. M.
Assoc. 1916, v. 67, p. 1508-1511.
59
Funk, Casimir: A report of researches dealing with the influence
_ of radium emanation on the activity of vitamines.—Proc. Soc. Exper.
Biol. and Med. 1916, v. 14, p. 9-10.
4. BIOLOGICAL PRODUCTS.
Blue, Rupert: The determination of the value of biologic prod-
ucts used in the prevention and treatment of the diseases of man and
the elimination of those which are without worth is a matter of
urgent need, meriting the earnest consideration of this association.—
J. Am. M. Assoc. 1916, v. 66, p. 1900.
Fischelis, Robert P.: A discussion of the methods of handling
_ biological products in the aete store.—J. Am. Pharm. Assoc. 1916,
v. 5, p. 841--845.
Marshall, George C.: An ast act of a thesis on animal drugs used
in medicine in England and France during the Middle Ages.—J. Am.
Pharm. Assoc. 1916, v. 5, p. 482-489.
Puckner, W. A.: Report of the council on Pharmacy and Chem-
istry of the American Medical Association on so-called secretin prepa-
rations. A review of the work by Carlson and his co-workers.—J.
Am. M. Assoc. 1916, v. 66, p. 208.
Carlson, A. J., Lebensohn, J. E., and Pearlman, S. J.: Researches
showing the questionable value of commercial preparations of
secretin.—J. Am. M. Assoc. 1916, v. 66, p. 178-185.
Robertson, T. B.: Researches on the isolation and properties of
tethelin, the growth-controlling principle of the anterior lobe of the
pituitary body.—J. Biol. Chem. 1916, v. 24, p. 409-421.
Williams, R. R.: A discussion of clinical, pathological, and chemi-
cal evidence against specificity of vitamines, and the possible nature
of active agents of dietary diseases—Am. Med. 1916, v. 11, p. 756-762.
Williams, Robert R.: The chemical nature of the “ vitamines.”
The antineuritic properties of the hydroxypyridines—J. Biol.
Chem. 1916, v. 25, p. 437-445.; see also v. 29, p. 495-520.
Funk, Casimir: A discussion of the chemical nature of the vita-
mines, their importance in metabolism and their function in the
animal organism.—Am. Med. 1916, v. 22, p. 751-756.
McCollum, E. V., Simmonds, N., and Pitz, W.: The distribution
‘in plants of the fat soluble A, the dietary essential of butter fat.—
Am. J. Physiol. 1916, v. 41, p. 361-363.
White, J. S.: A concise digest of the theory of Funk, and its bear-
ing on the important problem of nutrition—Pharm. J. 1916, v. 23,
p. 4.
Shie, Marvin D.: A discussion of the effects of vitamines on body
growth.—Cleveland M. J. 1916, v. 15, p. 232-237.
Voegtlin, Carl, and White, George F.: From experiments, it is
concluded that pure adenine can not acquire antineuritic propertics,
60
and that there is probably no direct relation between adenine and
antineuritic vitamines.—J. Pharm. & Exper. Therap. 1916, v. 9, p.
155-166.
Fischer, L.: Notes on the role of the vitamines in deficiency
diseases — Am. Med. 1916, v. 11, p. 774-775.
Macallum, A. B.: A review of the literature on the relation of
vitamines to animal growth.—Am. Med. 1916, v. 11, p. 782-784.
Vedder, E. B.: The relation of diet to beriberi and the present
status of our knowledge of vitamines. A general review and dis-
cussion of the subject with references to the literature—J. Am. M.
Assoc. 1916, v. 67, p. 1494-1497.
Salomon, H.: A discussion on the use ada value of yeast as an
article of diet—Physiol. Abstr. 1916, v. 1, p. 238; see also H. Wintz
and Max Rubner, Physiol. Abstr. 1916, v. 1, p. 238.
Lami, Pio: Notes on some of the pharmaceutical preparations of
cholesterin.—Boll. chim.-farm. 1916, v. 55, p. 83-10, 36-37, 70-74.
Cronin, John J.: A presentation of clinical data showing the
value of thromboplastin (tissue extract) as a hemostatic—J. Am.
M. Assoc. 1916, v. 66, p. 557-558.
Sanders, William: The chemistry and therapeutics of nuclein.—
Am. J. Clin. Med. 1916, v. 23, p. 757-759. |
Hill, Reuben L.: Observations on the effect of the injection of
animal extracts on mammary secretions.—Mulford’s Vet. Bull. 1916,
v. 7, p. 151-157. |
Vaughan, Victor C.: Protein poisons. Casein yields, under the
proper treatment, a large percentage of protein poison. The latter
is acid in character and does not give the ninhydrin reaction until
after being split up with an acid. The poison gives a skin reaction
in all persons and is not without harm when administered by
mouth.—J. Am. M. Assoc. 1916, v. 67, p. 68-69.
ENZYMES. .
Davis, W. A.: On the preparation of invertase for the determina-
tion of sucrose.—Chem. Abstr. 1916, v. 10, p. 2313.
Sherman, H. C., and Tanburg, A. P.: Notes on the preparation
ani! properties of the amylase of Aspergillus Oryze, the chief active
constituent of taka-diastase-—J. Am. Chem. Soc. 1916, v. 38, p. 1638-
1644.
Okada, Seizaburo: Experimental data showing the optimal condi-
tions for the proteoclastic action of taka-diastase——Biochem. J. 1916,
y. 10, p. 180-136.
Bodnar, J.: A description of a method for the determination of
the activity of amylase in the presence of alkaloids, An abstract.—
Chem. Zentralbl. 1916, v. 87, p. 37-38,
61
s Deleamu, N. T.: A proteolytic enzyme identical with that obtained
from Carica papaya was isolated from the latex of Ficus carica—
Physiol. Abstr. 1916, v. 1, p. 271.
E’we, G. E.: The papain examined varied in strength ranging
from 1:1 to 1:100 in egg-white digesting power.—Proc. Pennsyl-
vania Pharm. Assoc. 1916, p. 116.
Deleanu, N. T.: Researches showing the hydrolytic action of
papain on certain vegetable and animal proteins——Physiol. Abstr.
1916, v. 1, p. 80.
Swift, E. G.: Sixty per cent of the samples of papain examined
were of satisfactory quality, two of the samples were worthless and
‘three others less than one-half strength—Oil, Paint & Drug Rep.
1916, v. 90, No. 16, p. 46. ;
van der Haar, A. W.: A report of researches to determine the
chemical nature of oxidizing enzymes.—Physiol. Abstr. 1916, v. 1,
p- 203.
Bunzell, Herbert: A report of researches showing the mode of
action of oxidases.—J. Biol. Chem. 1916, v. 24, p. 91-102.
Dunning, H. A. B.: Urease is an enzyme found in many bacteria,
fungi, and in certain higher plants. It readily converts urea into
ammonium carbonate, and on this account it is not only interesting
but extremely useful as a diagonistic reagent. At present it is pre-
pared in considerable quantity from the soya bean.—J. Am. Pharm.
Assoc. 1916, v. 5, p. 808-811. :
de Graaff, W. C., and van der Zande, J. E.: The authors find that
soya beans sometimes contain bacteria capable of decomposing urea.
These bacteria are not the cause of the ureolytic action of the beans,
and no true urobacillus has been detected.—Chem. Weekblad, 1916,
v. 13, p. 258-264.
Mom, C. P.: The ureolytic properties of soya beans are due to the
action of Urobacillus Pasteurii, and not to the action of urease, as is
generally supposed.—Chem. Weekblad, 1916, v. 13, p. 72-75; see also
p. 255-257.
Groll, J. T.: Mom’s statement that the ureolytic action of soya
beans is due to bacteria and not to urease is not confirmed by the
author.—Chem. Weekblad, 1916, v. 13, p. 254-255.
Beijerink, M. W.: Notes on the occurrence of urease in the higher
plants—Chem. Weekblad, 1916, v. 13, p. 4438-444.
Mateer, J. G., and Marshall, E. K.: Data showing the urease con-
tent of certain beans, with special reference to the jack bean.—J.
Biol. Chem. 1916, v. 25, p. 297.
Webster, D. H.: On the cause of the ureolytic action of the soya
bean and on the influence of antiseptics, temperature, sunlight, age
62
of the seed, ete., on the reaction—Chem. Weekblad, 1916, v. 18
p. 663-677.
Bayliss, W. M.: A report of researches relating to the mode 0:
action of urease-—Physiol. Abstr. 1916, v. 1, p. 241.
Rahn, Otto: Researches to determine the influence of temperat
and of poisons on enzyme action, fermentation, and growth.—
Physiol. Abstr. 1916, v. 1, p. 77.
Folpmers, T.: A discussion of experimental investigations, the re-
sults of which indicate that tyrosinase is a mixture of two enzymes.-
Chem. Weekbiad, 1916, v. 18, p. 1282-1289.
ORGANOTHERAPY.
Fulk, M. E., and Macleod, J. J. R.: Evidence that the active prin-
ciple of the retroperitoneal chromaphil tissue has the same physio-
logical action as the active principle of the suprarenal gland.
Am. J. Physiol. 1916, v. 40, p. 21-29.
Editorial: The pineal body. A review of some of the striking
facts that have been brought to light in connection with the study
of the ductless glands.—J. Am. M. Assoc. 1916, v. 66, p. 860-361.
Fenger, Frederick: A presentation of analytical data showing the
composition and physiologic activity of the pineal gland.—J. Am,
M. Assoc. 1916, v. 67, p. 1836-1838.
Robertson, T. B., and Burnett, Theodore C.: Researches relating
to the influence of tethelin and other alcohol-soluble extractives from
the anterior lobe of the pituitary body upon the growth of car-
cimomata in rats.—J. Exper. M. 1916, v. 23, p. 631-639.
Harrower, Henry R.: An additional note on the therapeutic value
of spleen extract.—Med. Rec. 1916, v. 89, p. 1000-1001.
Goto, Michio: A report of researches dealing with the physio-
logical action of the extract of lungs.—Physiol. Abstr. 1916, v. 1,
p. 330.
Fischl, R.: A note on the value of lung extract as a local hemo-
static.—Physiol. Abstr. 1916, v. 1, p. 177.
Leighton, A. P.: Corpus luteum extract finds its principal use
in the treatment of functional amenorrhea; neuroses of the natural,
artificial, and premature menopause; and eases of ovarian deficiency,
such as dysmenorrhea.—Med. Press, 1916, v. 101, p. 9.
Hirst, John Cook: Corpus luteum extract as a remedy for nausea
in pregnancy. The favorable results obtained in five cases appear
to justify a continuation of the observations—J. Am. M. Assoc.
1916, v. 66, p. 645.
Rogers, John, et al.: A study of the effects of the subcutaneous
injection of organic extracts upon the flow of pancreatic secretion.—
Am..J. Physiol. 1916, v. 40, p. 12-15.
63
Rogers, John, et al.: A report of researches to determine the ef-
fects of organ extracts on gastric secretion—Am. J. Physiol. 1916,
-y. 39, p. 345-353.
_ von Zelinski, W. F.: A report of favorable results with mam-
mary extract in the treatment of menorrhagia——Am. J. Clin. M.
1916, v. 23, p. 915. |
For gdditionsl references to articles dealing with the subject of
organotherapy see J. Am. M. Assoc. and Index Med.
“af
7
>
SERUMS AND VACCINES.
Blue, Rupert: In the enforcement of the law regulating the propa-
gation and sale of viruses, serums, and toxins it is possible for the
Public Health Service to guard against the sale of contaminated
preparations. It insures to physicians the full strength of those
preparations for which standards have been devised, but it can not
guarantee the potency of preparations for which standards have not
been fixed, and which practitioners generally are being urged to use
in greater degree. In order to determine this potency, the medical
profession has a duty to perform.—J. Am. M. Assoc. 1916, v. 66,
p. 1900.
White, J. Stanley: A discussion of bacterial vaccines from the
point of view of the pharmacist.—Pharm. J. 1916, v. 97, p. 272-2738.
Schneider, Albert: Tuberculin and mallein and several of the
bacteriens should have been introduced into the present edition of
the Pharmacopeia.—Drug. Cire. 1916, v. 60, p. 693.
White, J. S.: The preparation of vaccines by the pharmacist is
advocated and directions for their preparation are given.—Pharm,
J. 1916, v. 97, p. 272-273.
Twining, Charles M.: A presentation of the subject of serum
manufacture in considerable detail, including the selection of the
animal, difficulties encountered in manufacturing, preservation of
serums, etc.—J. Am. Pharm. Assoc. 1916, v. 5, p. 21-29.
Anon.: Modified formulas for the preparation of a number of
different sera are presented.—Yearbook of Pharmacy, 1916, p. 59
from L’7Union Pharm. 1916, v. 57, p. 23-24.
~ Homer, Annie: A description of an improved method for effect-
ing the concentration of antitoxic sera. ye
p. 388-400; see also Biochem. J. 1916, v. 10, p. 280-307.
Heinemann, P. G.: Studies on the refinement and concentration of
antitoxins.—J. Infec. Dis. 1916, v. 19, p. 483-439.
Hess, Alfred F.: Studies on the separation of serum into coagula-
tive and noncoagulative fractions.—J. Exper. M. 1916, v. 24, p.
701-708.
64
Smith, Wallace: A description of a simplified method of produc-
ing a potent precipitin serum.—J. Med. Research, 1916, v. 84, p.
169-175.
Chick, Harriette: Methods for the preparation and use of certain
agglutinating sera.—Lancet, 1916, v. 190, p. 857-861.
Camus, L.: A discussion of the preparation, properties, and advan-
tages of a homogeneous vaccine.—Compt. rend. Acad. sc. 1916, v. 163,
p. 249-251.
Dean, H. R., and Adamson, R. S.: A description of a method for
the preparation of a nontoxic dysentery vaccine.—Brit. M. J. 1916,
v. 1, p. 611-614.
Thomson, J. D.: A description of attempts to produce a safe and
effective dysentery bacillus (Shiga) vaccine for prophylactic pur-
poses.—Brit. M. J. 1916, v. 1, p. 8303-805.
Amoss, Harold L., and Wollstein, Martha: A description of a
rapid method for the preparation of antimeningitis serum.—J.
Exper. M. 1916, v. 23, p. 403-417.
Caulfield, Alfred H.: A preliminary report on new methods for
the production of antistreptococcal sera.—J. Path. & Bact. 1916, v. 21,
p. 28-40.
Food, Edwin S., and Smith, Wallace V.: Experiments relative to
the production of a hyperimmune serum for infectious abortion in
mares.—J. Infec. Dis. 1916, v. 18, p. 897-401. _
Anon.: A general discussion of the development in the efficacy of
hog-cholera serum.—Mulford’s Vet. Bull. 1916, v. 7, p. 48-45.
Reichel, John: A discussion of the problem of how to concentrate
hoe-cholera serum.—Mulford’s Vet. Bull. 1916, v. 7, p. 64-68.
Reichel, John: A report of experiments to determine the relative
value of trikresol and carbolic acid in the preservation of hog-cholera
serum.—Mulford’s Vet. Bull. 1916, v. 7, p. 61-64.
Bristol, Leverett D.: A discussion of the value of toluol in the
sterilization of vaccines made from nonsporogeneous gram negative
bacteria.—New York M. J. 1916, v. 104, p. 360-361.
Franklin, O. M., and Haslan, T. P.: Analytical data relative to
the strength and composition of blackleg vaccines.—J. Infec. Dis.
1916, v. 19, p. 408-415.
Puckner, W. A.: The “ Mark White Goiter Serum ” and the “ Mark
White Iodinized Oil.” Comments on the method of exploiting these
preparations.—J. Am. M. Assoc. 1916, v. 67, p. 967.
Zung, Edgard, and Gelat, Maurice: A report of experiments to
determine the effect of serum treated with agar.—J. Exper. M. 1916,
y. 2h, p. 247-269,
'Tektoen, Ludvig: A general discussion on the subject of vaccine
treatment.—J. Am. M. Assoc. 1916, v. 66, p. 1591-1594.
_ Hastings, Thomas W.: Attention is called to the abuse of vaccine
therapy. In this connection it is stated that the commercial use of
polyvalent vaccines, without specific diagnoses, should be discon-
tinued.—J. Am. M. Assoc, 1916, v. 66, p. 1742.
Cruet, P., and Rousseau, E.: A chemical and bacteriological study
D shiorinated serum.—Bull. se. pharmacol. 1916, v. 23, p. 271-276.
_ Hirschfelder, J. O.: A description of a simple miueied for the
‘quantitative determination of complement fixation—J. Am. M.
Assoc. 1916, v. 66, p. 1386-1387.
~ Wehrbein, Heinrich: Studies on the relationship between serum
reactions —J, Infec. Dis. 1916, v. 19, p. 806-810.
~ Glynn, Ernest, and Lowe,_E. C.: A classification of serum reac-
ons of 300 ae cases of “enteric” with the Oxford standard
ag 9, p. 222-227.
~ Dean, H. R.: The Pet thikics of the serum reaction. A summary
‘of views on precipitation, complement fixation, and agglutination.—
Brit. Med. J. 1916, v. 2, p. 749-752.
Werigo, B.: The cause and mechanism of anaphylaxis based on
the experiences of Mélik-Megrabov.—Compt. rend. soc. biol. 1916, v.
79, p. 87-88.
Danysz, J.: A theory for the cause of anaphylaxsis and a discus-
sion of the nature and formation of antibodies——Compt. rend. acad.
se. 1916, vy. 163, p. 985-989.
Weil, R.: A report of further studies on serum sickness.—Proce,
‘Soc. Exper. Biol. & Med. 1916, v. 14, p. 60-61.
_ Anon.: A book review calls attention to the third edition of a
volume by William C. Bosanquet and John W. H. Eyre entitled
Serums, Vaccines, and Toxins in Treatment and Diagnosis—Lancet,
1916, v. 191, p. 21; see also Brit. M. J. 1916, v. 1, p. 887.
Achard, Ch., and Foix, Ch.: Oil emulsions are found to be serv-
iceable vehicles for vaccines from paratyphoid bacilli, but im-
munity does not follow their use so rapidly as that of aqueous
-yehicles.—Compt. rend. soc. biol. 1916, v. 79, p. 209-211.
_ For additional references to articles on serums and vaccines see
J. Am. M. Assoc.; J. Infec. Dis.; Chem. Abstr.
BIOLOGICAL METHODS AND TESTS.
Smith, J. W., jr., and MacNeal, W. J.: A comparative study of the
‘different methods of performing the Wassermann test for syphilis.—
“Proc. Soc. Exper. Biol. & Med. 1916, v. 14, p. 7-8; see also J. Im-
munol. 1916, v. 2, p. 75-93.
Liot, A., and Larsonneau, A.: Remarks on the procedure for
carrying out the Wassermann reaction.—Bull. sc. pharmacol. 1916,
Vy. 23, p. 277-283.
110095°—19——5
PEs ete
\
66 ——
Ottenberg, R.: Notes on the correct and incorrect methods of pe
forming the daily titrations for the Wassermann reaction and other
forms of complement fixation—J. Lnmunol. 1916, v. 2, p. 39-46.
Halle, W., and Pribram, E.: A method is described for performing”
a Wassermann test by means of hollow glass slides, which is stated
to be more rapid and economical] than the ordinary method.—Chem.
Zentralbl. 1916, v. 2, p. 608. .
Fildes, P., and McIntosh, James: A description of a method for
the application of the Wassermann reaction in large numbers.—
Lancet, 1916, v. 191, p. 751-753. :
Ruediger, E. H.: A report of investigations of methods for the
preservation of human serum for use in the Wassermann reaction.—
Philippine J. Sc. 1916, v. 11, sec. B, p. 1-17, 87-104.
Fonss, A. L.: A discussion of some of the defects of the Wasser-
mann reaction.—Med. Review, 1916, v. 19, p. 5.
Anon.: By a “ provocative Wassermann ” 1s meant a positive Was-—
sermann test produced as the result of an injection of salvarsan. It
has been definitely established that if a patient is syphilitic, a nega-
tive Wassermann test may be converted into a positive one by the in- —
jection of salvarsan. This is due to the fact that spirochetes are
killed and their toxic action is temporarily icreased.—J. Am. M.—
Assoc. 1916, v. 66, p. 1487.
Haller, David A.: Variations in the strength of positive Wasser- —
man reactions in cases of untreated syphilis—J. Am. M. Assoc. ©
1916, v. 66, p. 882-884. ;
Sellards, Andrew W., and Minot, George R.: A study of the an-~
tagonistic action of negative sera upon the Wasserman reaction.— —
J. Med. Research, 1916, v. 34, p. 1381-147.
Falls, Frederick H., and Moore, Josiah J.: A discussion of re-—
searches to determine the value of the Wasserman test in bres, q
nancy.—J. Am. M. Assoc. 1916, v. 67, p. 574-579. .
Olson, George Manghill: Comments on the interpretation of the
Wasserman reaction.—Journal-Lancet, 1916, v. 36, p. 46-47.
Ladd, John M.: An analysis of 1,000 Wasserman reactions.—New —
York M. J. 1916, v. 104, p. 952.
Lyons, Randolph: Experimental data showing the influence of
potassium iodide on the luetin test.—Southern M. J. 1916, v. 9,
p. 487-490.
Kolmer, J. A., Malsunami, T., and Broadwell, S.: Experiments
conducted by the authors show that the luetin test for syphilis is
valueless unless all possible chances of reaction from alkali iodides
are carefully excluded.—J. Am. M. Assoe, 1916, v. 67, p. 718-719.
Gray, Carl D.: A comparison of the iodine urinary test for
syphilis with the W asserman reaction.—Med, Ree. 1916, v, 89, p. 821-_
823.
67
MeNeil, H. L.: A critical study of the Wasserman and luetin re-
ions done simultaneously on 500 cases.—Southern M. J. 1916, v. 9,
P. 202-205.
Flood, BE. P.: A study of von Dungern’s test for syphilis indicates
that it is of no value in serum diagnosis: —J. Immunol. 1916, v. 2,
))p. 69-74.
~ Griswold, Don M.: A description of the Schick test for diphtheria,
accompanied by some of the author’s notes.—J. Lab. & Clin. Med.
1916, v. 1, p. 441-443.
-Zingher, Abraham: Directions for controlling the seudo reactions
in the Schick test —J. Am. M. Assoc. 1916, v. 66, p. 1617-1618.
) Park, William H., and Zingher, Abraham: The determination of
natural, active, and passive diphtheria immunity by the Schick
test—Am. J. Public Health, 1916, v. 6, p. 431-445.
Stovall, W. D.: Schick’s test, when employed together with swabs,
is a prompt, economic, and satisfactory method of quelling epidemics
of diphtheria. It requires no special technic that can not be easily
acquired by any physician, and therefore is available to all—J. Am.
M. Assoc. 1916, v. 66, p. 804-806.
Weaver, George H., and Rappaport, B.: Further observations on
the Schick test for diphtheria immunity.—J. Am. M. Assoc. 1916,
v. 66, p. 1448-1450.
Koplik, Henry, and Unger, Lester J.: A description of a simple
method for the application of the diphtheria toxin skin reaction.—
J. Am. M. Assoc. 1916, v. 66, p. 1195-1196.
Tsabolinsky, M. P.: An explanation of the mechanism of the Ab-
derhalden’s reaction in infectious diseases.—Physiol. Abstr. 1916,
v. 1, p. 544.
Hiissy, Paul: A survey of the present status of the Abderhalden
ferment reaction.—Schweiz. Apoth.-Ztg. 1916, v. 54, p. 105-108, 121
124, 133-136.
Bronfenbrenner, J.: The present status of the Abderhalden reac-
tion and of the theory of the so-called “ abwehrferfemte.”—J. Lab.
& Clin. Med. 1916, v. 1, p. 79-112.
Peterson, V.: Comments on the contradictory nature of the litera-
ture on Abderhalden’s dialysis reaction in tuberculosis, with tabu-
lated details of the results of the author’s own experiments. An ab-
stract—J. Am. M. Assoc. 1916, v. 67, p. 550.
Seiffert, G.: An article showing the advantages of the use of
dried organs for the Abderhalden reaction.—Physiol. Abstr. 1916,
vy. 1, p. 254.
Singer, H. Douglas, and Quantz, William B.: Experimental data
showing the effects of ammonium salts on the Abderhalden test.—
Arch. Int. Med. 1916, v. 18, p. 538-540,
68
Rivas, D., and Buckley, Albert C.: Studies on the bacteriologiea
aspect of the Abderhalden test—J. Med. Research, 1916, v. 33, 7
297-304, 7
Smith, G. H., and Cook, M. W.: A study of the mechanism of th
Abderhalden reaction with bacterial substrates ——J. Infec. Dis. 191
v. 18, p. 14-19.
Elsesser, Oscar J.: A report of experiments to determine the
specificity of the Abderhalden reaction with vegetable proteins.
J. Infee. Dis. 1916, v. 19, p. 655-681.
Davison, Wilbert C.: The diagnosis of enteric fever (typhoi
and parat? y agglutinati sts.—J. Am. M. Assoe.
1916, v. 66, p. 1297-1300.
Coles, A. C.: A description of an easy and rapid method of apply-
ing Widal’s reaction for the diagnosis of typhoid fever.—Brit. M. J.
ISL6Sv1, p. 684:
Walker, E. W. A.: A note on Widal’s reaction with standardize
agelutinable cultures.—Lancet, 1916, v. 190, p. 16-19.
Walker, E. W. A.: An application of drop-measuring to the
Widal technique.—Lancet, 1916, v. 191, p. 552-554.
Sladden, A. F. S.: A discussion oH an sung in the Widal reac-
‘ tien—the occurrence of “
p. 202-275.
Dreyer, Georges, and Walker, E. W. A.: The diagnosis of the
enteric fevers in moculated individuals by the agglutinin reaction.—
Lancet, 1916, v. 191, p. 419-423.
Garrow, R. P.: The relation of the angle of the dropping pipette
to the accuracy in agglutination technique.—Lancet, Be v. -10ig
p. 863.
Riebold, G.: The diagnostic value of the Gruber-Widal reaction
in persons vaccinated against typhoid fever.—Chem. Zentralbl. 1916,
v.-81,;p. 1160:
Kahn, Max, and Wechsler, Lawrence: A study of the diagnostie
value of the Russo reaction for typhoid—Med. Ree. 1916, v. 89, p.
106-107.
Kronberger, H.: Notes on the value of the cutaneous tuberculin
reaction.—Deutsch. med. Wchnschr. 1916, v. 42, p. 7538-754.
Craig, D. A.: Notes on the cutaneous tuberculin test by puncture
with : > Vv. 67, p. 1227,
Corper, H. J., and Callahan, F. F.: A discussion of the diazo-and
urochromogen reactions as prognostic aids in pulmonary tuberculo-
.& Clin. Med. 1916, v. 1, p. 740-746.
Cutter, Irving S., and Morse, Max: An account of experiences
with the Kiutsi-Malone urinary test for pregnacy—J. Am. M.
Assoc. 1916, v. 66, p. 559-560.
?
69
; _ Chace, Arthur F., and Myers, Victor C.: A report of investigations
to determine the value of recent laboratory tests for the diagnosis
and treatment of nephritis—J. Am. M. Assoc. 1916, v. 67, p. 929-932.
— Schurmarin, W.: Observations on the thermoprecipitin reaction of
Ascoli and Valenti for the diagnosis of gonorrhea.—Chem. Zentralbl.
1916, v. 2, p. 513.
Additional references to articles dealing with the application of
_yarious biological tests appear in J. Am. M. Assoc.; J. Biol. Chem.;
J. Immunol.; Index Med.; J. Lab. & Clin. Med.; Lancet; and
- Brit. M. J.
P on 5. ANTISEPTICS AND DISINFECTANTS.
Lambert, Robert A.: A report of experiments to determine the com-
parative resistance of bacteria and human tissue cells to certain com-
mon antiseptics.—J. Exper. M. 1916, v. 24, p. 683.
3 Lumiére, A.: A comparative study of the action of antiseptics on
“pure cultures and in the presence of pus.—Compt. rend. acad. se.
~ 1916, v. 163, p. 309-311.
Hoekert, B. E.: Disinfectants and disinfecting. Advice on the
selection of the proper disinfectant for the particular purpose to be
accomplished:—A pothecary, 1916, v. 18, No. 10, p. 22-23; see also
Proc. Connecticut Pharm. Assoe. 1916, p. 98-108. ,
Williams, Seward W.: A discussion of gaseous disinfection, in-
eluding a symposium by State health officers and others on the sub-
ject—J. Am.’Pharm. Assoc. 1916, v. 5, p. 185-194, 273-285, 391-399.
Leclair, E., and Logié, G.: On the use of the mixed vapors of for-
maldehyde and benzine for disinfecting purposes.——Bull. se.
pharmacol, 1916, v. 23, p. 46-47.
Norton, John F., and Hsu, Paul H.: The physical chemistry of
J. Infec. Dis. 1916, v. 18, p. 180-194.
Kilmer, Fred B., et al.: A presentation of experimental data show-
ing the phenol coefficient of a number of germicides, with comments
on the Hygienic Laboratory method for the determination of the
phenol coefficient —J. Ind. & Eng. Chem. 1916, v. 8, p. 45-47.
Walker, J. T. A.: A critical comparison of the Hygienic Labora-
tory and Rideal-Walker tests for the standardization of disinfeec-
tants.—New York M. J. 1916, v. 103, p. 500-505.
Emery, W. de E.: A description of a standard method of testing
antiseptics for wounds, with some results.—Lancet, 1916, v. 190,
p- 817-819.
Bond, C. J.: A study of the influence of antiseptics on the activities
of leucocytes and on the healing of wounds.—Brit. M. J. 1916, v. 1,
p. (77-782.
70
\
Dakin, H. D., et al.: Experimental data showing the antiseptic
action of Shee of the chloramine group.—Proc. Roy. Soe. Lond.
1916, Sec. B, v. 89, p. 232-250; see also Brit. M. J. 1916, v. 1, p.
160-162; Brit. M. J. 1916, v. 1, p. 388. |
Leitch, Archibald: A ee on the value of brilliant-green as an
antiseptic. Aqueous solutions, 1 in 500,000 are appr phn equiv-
alent to 1 in 50,000 of mercuric chloride—Brit. M. J. 1916, v. 1,
p- 236-237.
Jacoby, Martin: A study of the influence of antiseptics on urease.
Urease is practically unaffected by toluol, but is extremely sensitive
to oil of mustard and to sodium fluoride——Physiol. Abstr. 1916, v. 1,
p. 242.
De Witt, Lydia M., and Sherman, H.: An investigation of the
bactericidal and fungicidal action of copper salts—J. Inf. Dis. 1916,
yv. 18, p. 868-382.
4, ANALYTICAL DATA. od
For analytical data showing the composition of “ Wine of Cardui”
and other proprietary remedies see Rep. Chem. Lab. Am. M. Assoc.
1916, v. 9, p. 46-129.
Gutbier, A.: A review of the analytical chemistry of metalloids,
with numerous references to the literature——Chem.Ztg. 1916, v. 40,
p. 245-249, 276-277, 303-304, 315-316, 326-328.
KKindscher, E.: An account of new work in the fields of cask
analysis, colorimetry, volumetric and gravimetric analysis——Chem. —
Zentralbl. 1916, v. 2, p. 770. ;
Anon.: A book review calls attention to William T. Hall's transla- —
tion of the eighth German edition of F. P. Treadwell’s Analytical —
Chemistry, v. 1—J. Am. Chem. Soc. 1916, v. 38, p. 1645-1646.
Anon.: A review of a volume by Frank Austin Gooch, Representa-
tive Procedures in Quantitative Chemical Analysis, states that to the
expert the book is one which may safely be recommended as a very
useful guide—Pharm. J. 1916, v. 96, p. 308.
Anon.: A review of the second edition of a volume by A. C. Cum-
ming and S. A. Kay, entitled Zertbook of Quantitative Analysis.
The subdivisions are voluemetric analysis, colorimetric methods, sys-
tematic quantitative analysis, analysis of simple ores and alloys,
gas analysis, water analysis, quantitative analysis of organic sub-
stances and the determination of molecular weights.—Chem. & Drug.
1916, v. 88, No. 1920, p. 34.
Anon.: A book review calls attention to a volume by Albert
Schneider entitled Bacteriological Methods in Food and Drugs
Laboratories, with an Introduction to Micro-analytical Methods —
Pharm. J. 1916, vy. 96, p. 75.
71
1, ADULTERATIONS.
Scoville, W. L.: Since the U. S. P. IX sets a standard. compre-
hending a maximum, as well as a minimum, strength, the prepara-
‘tion must be within these limits or it is liable to seizure as adul-
pened and the owner fined.—Pacific Pharm, 1916, vy. 10, p. 122
Berg, Frank F.: A discussion of the adulteration and sophistica-
ion of drugs, chemicals, and pharmaceutical products. ee
Mountain Druggist (The), Denver, 1916, v. 30, No. 8, p, 26-2
_ Weigle, George J.: Adulteration and nebeenae of Sieh are of
‘two kinds—the one springs from deliberate purpose, the other is
usually the product of carelessness. The one is just as dangerous as
ihe other.—Proc. Wisconsin Pharm. Assoc. 1916, p. 61.
Beri nger, George M.: A general discussion of the Pharmacopoeia
a aaiiohal safeguard against adulteration states that there is
| scarcely a question relating to the quality of the commonly used
drug products which can not be answered, either directly or indi-
‘rectly, through the information contained in this volume.—J. Am.
Pharm. Bee. 1916, v. 5, p. 603-606.
Wilbert, M. I.: A discussion of the variation in purity and
strength of widely used drugs and preparations in their relation to
the physician and the patient. —Public Health Rep. 1916, v. 31, p.
2072-2076. |
Eldred, F. R.: The scarcity of certain drugs and chemicals caused
by the war has undoubtedly increased the adulteration and lowered
} the quality of some of these products. Probably the majority of the
‘drugs and chemicals have not been so affected, but, on the whole, it
seems that the effect has been quite noticeable-——Oil, Paint & Drug
Rep. 1916, v. 90, No. 16, p. 46.
Parke, Davis & Co.: So far as we are aware, we have been receiv-
ing drugs of good quality and have not received any shipments
which, due to the scarcity and prevailing high price, have been adul-
terated to any extent—Oil, Paint & Drug Rep. 1916, v. 90, No. 16,
p. 46.
Kline, C. Mahlon: In commenting on the drug situation, it is stated
that the present quality is markedly inferior to that offered before
the war. It seems as though collectors and dealers had hunted up all
the drugs for which they were unable to secure a market prior to the
present scarcity, and not only offered them for sale, but succeeded in
making sales at high prices.—Oil, Paint & Drug Rep. 1916, v. 90,
No. 16, p. 46.
Swift, E. G.: The growing scarcity of potassium salts has led to
the offering of technical salts for those of medicinal quality. The
former usually contain large proportions of chloride and are far
“below the U.S. P. and N. F. standard.—Oil, Paint & Drug Rep. 1916,
vy. 90, No. 16, p. 46.
72
2. REAGENTS AND TEST SOLUTIONS.
Bordier, T.: As reagents for testing the efficacy of nonactinic gla
bottles, the author recommends a dilute solution of iodine prepared
by adding 10 drops of tincture of iodine to 1 liter of water, or a
similar solution to which has been added a little freshly prepared
starch paste—Compt. rend. acad. sc. 1916, v. 163, p. 105.
Sage, C. Edward: Notes on the evaluation of acetic anhydride for
use as a reagent.—Perf. & Ess. Oil Rec. 1916, v. 7, p. 388; see also
comments by C. Edward Sage, p. 162-163, and L. Guy Radcliffe and
S. Medofski, p. 163-165.
Francois. Maurice: On the use of rosaniline bisulphite as a reagent
for detecting glycerides of the fatty acids——Farm. Espan. 1916, v. 48,
p. 551-558, 567-569, 583-585.
Anon.: A note on the use of vanillin hydrochloride as a reagent for
the identification of volatile oils. An abstract—Ann. Falsif. 1916,
v. 9, p. 480.
Fouchet, A.: A note on the preparation of sodium hypobromite
reagent for use in the determination of urea.—J. pharm. et chim.
1916, v. 14, p. 366-368.
Ericson, Antipas: A method for the preparation of a stable starch
solution consists of heating the starch with water and adding a small
amount of normal KOH solution.—Svensk farm. Tidskr. 1916, vy. 20,
p. 499. :
Lorenz, A. W.: A note on the sensitiveness of the iodo-starch
reaction.—Chem.- Analyst, 1916, No. 19, p. 20-21.
Shipley, J. W.: Experiments with the use of sodium pyrogallate
as a reagent for the determination of oxygen.—J. Am. Chem. Soe.
1916, v. 38, p. 1687-1701.
Ivanoo: A 2 per cent solution of sodium bisulphide is recom-
mended as a very sensitive reagent for the detection of lead. The
sensibility is stated to be 1:1,000,000. An abstract.—J. pharm. et
chim. 1916, v. 18, p. 3859-860.
Sieborg, Ernst: A study of the formaldehyde-sulphurie acid re-
action for tannin or gallic acid to determine the configuration nec-—
essary in the molecule to give positive results—Physiol. Abstr.
1916, v. 1, p. 284.
Anderson, R. P., et al.: Studies relating to the preparation and
purification of reagents for use in gas analysis.—J. Ind. & Eng.
Chem. 1916, v. 8, p. 24-26, 131-136, 999-1001.
Reed, G. B.: A comparison of the efficiency of the color reagents
used for work on oxidases with regard to the degree of oxidation re-
quired to give an appreciable color change.—-Bot. Gaz. 1916, v. 61, p.
430-432,
73
__ Setlin, J.: A note on the use of copper sulphate for the prevention
of the growth of molds in micro-reagents.—J. Am. M. Assoc, 1916, v.
67, p. 1387,
Pempson, H. L.: A discussion of the volumetric solutions of
the U.S. P. VIII and IX and of the methods for their standardiza-
tion—Proe. Nebraska Pharm. Assoc, 1916, p. 96-101.
Clark, A. H.: A description of a scheme for the preparation of
large quantities (20 to 40 liters) of volumetric solutions.—J. Am.
Pharm. Assoc. 1916, v. 5, p. 706-708.
Blanchetiére: A report of an investigation of methods for the
“a standardization of oxalic acid volumetric solution.—Bull. Soe. chim.
_ France, 1916, v. 19 and 20, p. 300-308,
3. INDICATORS.
Anon.: A reprint of Langslow’s indicator table. Taken from
» Apoth.-Ztg. 1915, v. 30, p. 241—Am. Druggist, 1916, v. 64, No. 1,
op. 26,
I. M. K.: A book review of a volume by Dr. Niels Bjerrum en-
titled Die Theorie der alkalimetrischen und azidimetrischen Tit-
rierungen.—Chem. Weekblad, 1916, v. 13, p. 446.
Viehoever, Arno, ara Ewing, Carl O.: A presentation of re-
sults obtained in researches to determine the sensitivity of some
commercial litmus papers—J. Am. Pharm. Assoc. 1916, v. 5, -p.
599-602.
Dott, D. B.: From experiments, the author concludes that cochineal
is superior to methyl orange as an indicator for the titration of
‘alkaloids since the end reaction is more pronounced than with the
latter—Pharm, J. 1916, v. 96, p. 368; see also Ann. Falsif. 1916, v.
9, p. 820.
Crozier, W. J.: A report on some indicators extracted from animal
tissues.—J. Biol. Chem. 1916, v. 24, p. 443-445.
-Wegscheider, Bud: A theory for the action of acidimetric indica-
tors. An abstract.—Chem. Zentralbl. 1916, v. 87, part 1, p. 348-344.
Lubs, H. A. and Acree, S. F.: On the sulphonthalein series of indi-
cators and the quinone-phenolate theory— J. Am. Chem. Soc. 1916,
v. 38, p. 2772-2784.
Sacher, J. F.: A discussion of the use of soap as an indicator in
the titration of solutions containing coloring matters.—J. Soc. Chem.
Ind. 1916, v. 35, p. 1084.
Norton, John F., and Knowles, H. I.: A study of indicators for
the determination of temporary hardness of water.—J. Am. Chem.
Soe. 1916, v. 38, p. 877-884.
Kay, Sydney A., and Newlans, Susan H.: A report of researches
_ dealing with the use of methyl red as an indicator for the determina-
74
tion of the hardness of natural waters.—J. Soc. Chem. Ind. 1916,
v. 85, p. 445-447. “a
Clark, W. M., and Lubs, H. A.: A description of indicators for —
the colorimetric determination*of the hydrogen-ion concentration of
Sica Ha ee culture media.—J. Washington Acad. Se. py v.
6, p. 483-489.
Kelley, G. L., and Conant, J. B.: Experiments with the use of
diphenyl glyoxime as an indicator in the volumetric determination
of nickel by Frevert’s method.—J. Ind. & Eng. Chem. 1916, v. 8,
p. 804-807.
Kolthoff, I. M.: A discussion (with experimental data) of the
apparent paradoxical action of solutions of zinc salts and various
indicators.—Chem. Weekblad, 1916, v. 18, p. 1016-1019.
Fichter, Fr.: A report of experiments showing the relation be-
tween the hydrolysis of alkali salts and their reaction toward litmus.
An abstract.—Chem. Zentralbl. 1916, v. 87, part 1, p. 948.
4. PHYSICAL CONSTANTS.
Harkins, William D., and Humphery, E. C.: A report of investi-
gations with the drop weight method for the determination of sur-
face tension.—J. Am. Chem. Soc. 1916, v. 38, p. 228-236.
SPECIFIC GRAVITY.
Anon.: Notes on the methods for the determination of specific
gravity.—Pharm. J. 1916, v. 97, p. 367-368.
Bruhns, G.: A description of a method for the simplification of
picnometer weighing.—Chem.-Ztg. 1916, v. 40, p. 488.
Stratton, 5S. W.: Detailed descriptions of methods for the testing
of hydrometers.—Cire. Bur. Stand. 1916, No. 16, p. 1-16; see also
Circ. Bur. Stand. 1916, No. 59, p. 1-13.
Wright, C. H.: Notes on the determination of the specific ovavity
of fixed oils in the Tropics——J. Soc. Chem. Ind. 1916, vy. 35, p.
457-458.
SOLUBILITIES.
Diekman, George C.: The statements concerning solubilities
quoted in the U. S. P. IX are not intended as physical constants
in any strict sense of the term, but primarily as information re-
quired by physicians and pharmacists in connection with the dispens-
ing and preparing of medicines.—Pract. Drug. 1916, v. 34, No. 10,
p.,27.
Hildebrand, Joel H.: A general article on the subject of solu-
bility, with special reference to Raoult’s law.—J. Am. Chem. Soe.
1916, v. 38, p. 1452-1478.
75
Sill, Herbert F.: Data showing the influence of pressure on solu-
bility —J. Am. Chem. Soc. 1916, v. 38, p, 2632-2643.
3 Harkins, William D., et al.: The effect of salts upon the solubility
_ of other salts—J. Am. ae Soc. 1916, v. 38, p. 2709-2717.
Aita, A.: A study of the causes hae ae iat the solubility of
difficultly Saluble phosphates in citric acid.—Ann. chim. applicata.
1916, v. 6, p. 119+131.
Colani, A.: Data showing the solubility of alkaline oxalates in
_ the presence of certain other alkaline salts —Bull. soc. chim. France,
1916, v. 19 and 20, p. 405-407.
_ Jacobson, C. A., and Holmes, A.: Data on the solubility of vari-
ous salts of lauric, myristic, palmitic, and stearie acids.—J. Biol.
MChem. 1916, v. 25, p. 29-55.
_ Anon.: An abstract of V. M. Isnardi’s experiments on the solx-
bility of some of the common metals in water. The solubilities of
* lead, iron, copper, zinc, tin, silver, and of steel were determined.—
EPharm. We 1916, v.96, p. 7.
Bolenbaugh, Albert: A summary of the conclusions of experi-
ments on volume changes produced by the solution of certain salts.
The contraction values of some solutions of different strengths are
presented in the form of a table—J. Am. Pharm. Assoc. 1916, v. 5,
p. 38-39.
Groll, J. Temminck: A Aeenasion of various methods of pr sa ing
colloidal gold solutions—Chem. Weekblad, 1916, v. 13, p. 617-722
Marden, J. W.: On the solubilities of the sulphates of nee
strontium, calcium, and Jead in ammonium acetate solutions at
25° C., and a criticism of the present methods for the separation of
these substances by means of ammonium acetate solution.—J. Am,
hem. Soc. 1916, v. 38, p. 310-316; see also Chem. Abstr. 1916, v. 10,
p. 728.
Novack, H. J.: Physical phenomena pertaining to solution and
erystallization. A general discussion of the properties of molecules,
atoms, electrons, and ethereal corpuscles as evidenced in connection
_ with the phenomena of solution and crystallization —J. Am. Pharm.
- Assoc. 1916, v. 5, p. 964-974.
' Marden, J. W., and Dover, Mary V.: A presentation of experi-
~ mental data on the solubilities of several substances in mixed non-
aqueous solutions.—J. Am. Chem. Soc. 1916, v. 38, p. 1235-1240.
MELTING POINT DETERMINATIONS,
Parry, Ernest J.: The habit of “enlarging” melting points by 2°
(acetanilide 112°-114°, phenacetin 133°-135°, benzoic acid 120°-122°)
as practiced in the U. S. P. TX is thought to be objectionable.—Chem.
& Drug. 1916, v. 88, No. 1913, p. 40.
76
Monhaupt, M.: An illustrated description of an improved method
for the determination of the melting point of fats—Chem.-Ztg. 1916,
v. 40, p. 676.
Anon.: A book review calls attention to a volume by R. Kemf con-
taining tables of the most important organic compounds arranged
in the order of their melting points.—Chem.-Ztg. 1916, v. 40, p. 438.
BOILING POINT DETERMINATIONS.
Plummer, H. C.: A discussion of a formula for the calculation of
the boiling points of homologous compounds.—Phil. Mag. 1916, v. 32,
p. 371-381.
Smits: An illustrated description of a modification of Smits’
apparatus for the determination of boiling points—Chem. Week-
blad, 1916, v. 18, p. 1296.
THERMOMETRY.
Woodhead, G. S., and Jones, P. C. V.: An historical account of the
development of clinical thermometry, with full descriptions of the —
various instruments used.—Laneet, 1916, v. 190, p. 173-180, 281-287, ~
338-341, 495-501.
Hammerschmidt: Notes on the Fahrenheit thermometer with re-_
spect to its Inconvenient divisions.—National Drug Clerk, 1916, v. 4,
p. 427, 482.
Schliiter, H.: A detailed description of methods and formulas for
the calculation of the column correction for standardized thermom- —
eters.—Chem. Zentralbl. 1916, v. 1, p. 1213.
Lyons, A. B.: A list of errata in the alcoholometrical tables in the —
earlier printings of the U. S. P. IX.—Pacific Pharm. 1916, y. 10, —
p>, LoL.
Wheeler, E. G.: A graph based upon the ordinary formula for
stem correction of thermometers is given.—J. Soc. Chem, Ind. 1916,
v. 35, p. 1198-1200.
Churchill, B. P.: A thermometer that would render the most
efficient service to humanity must start at zero as the freezing point
and take the blood heat of man as 100°, these being the most vital
points in temperature pertaining to our comfort and safety.—J. Am.
M. Assoc. 1916, v. 66, p. 1842.
POLARIZATION AND REFRACTION,
Parry, Ernest J.: A special chapter is devoted to the subject of
refractive index in the new U. 8S. P. The test, however, is omitted
in almost every case where the property has been well defined. Re-
fractive indices are not given for fatty oils and rarely for volatile
oils—Chem. & Drug. 1916, v. 88, No. 1913, p. 40.
77
Ss ‘Parry, Ernest J.: The expression “rotation of a ray of polarized
| light, * which is found in the U. S. P. IX in the chapter on optical
rotation is inaccurate—Chem. & Drug. 1916, v. 88, No. 1913, p. 40.
_ Patterson, Thomas S.: A study of ‘the hanes: of solvents, ete.,
| ten the rotation of Peticatly active compounds.—J. Chem. Soe. Lond.
) 1916, v. 109, p. 1176-1228.
a Betti, M., and Conestabile, G. C.: A report of researches to deter-
mine the influence of substituting groups on ee rotatory power bie
se organic compounds.—Gaz. Chim. Ital. 1916, v. 46, p. 200-210;
also Betti, p. 220-225.
_ Roberts, C. C.: A discussion of a formula for the conversion of
scale readings on the Zeiss butyro-refractometer to refractive in-
dices.—Analyst, 1916, v. 41, p. 376.
_ Foresman, G. K.: A description of a simple, cheap, and satisfac-
Riory sodium lamp for the polariscope.—J. Ind. & Eng. Chem. 1916,
_y. 8, p. 165.
“i Fr erichs, G.: A description of a ee sodium flame lamp for
_ polarimetric work.—A poth.-Ztg. 1916, v. 31, p. 94.
Bates, Frederick, and con. Richard F.: Constants of the
- quartz-wedge saccharimeter and the specific rotation of sucrose.—
-Buil. Bur. Stand. 1916, v. 13, No. 1, p. 67-128.
Hudson, C. S.: Experimental data showing some numerical rela-
tions among the rotatory powers of the compound sugars.—J. Am.
Chem. Soe. 1916, v. 38, p. 1566-1575.
_ Foulkes, D.: Experimental data showing the variations of the
rotatory powers of galactose and TS in propyl aleohol at
different concentrations—J. pharm. et chim. 1916, v. 14, p. 364-366.
“«
te,
5. CHEMICAL CONSTANTS.
Issoglio, Giovanni: A description of a method for the determina-
tion of the oxidation numbers of medicinal fats. The oxidation
number is the amount of oxygen necessary to oxidize the products
obtained by steam distillation from 100 grams of fat—Ann. chim.
applicata. 1916, v. 7, p. 187-199.
ACID NUMBER,
Slack, H. F.: A description of a new method for the determina-
> tion of the acid value of oils, fats, and waxes.—Chem. & Drug. 1915,
v. 87, p. 673-674; Chem. Abstr. 1916, v. 10, p. 827.
Holland, E. B., et al.: A method for the determination of the acid
number of fats is described.—Chem. Abstr. 1916, v. 10, p. 1940 from
Bull. Massachusetts Agric. Exper. Sta. 1915, No. 166, p. 91-158.
Cranfield, H. T.: Data showing the relationship between the
Kirschner and Polenske values for 31 samples of butter are pre-
~ sented.—Analyst, 1915, v. 40, p. 489-442.
A
78 a
ESTER NUMBER,
Slack, H. F.: A new method for the determination of the ester
value of fats, fixed and essential oils, and waxes—Chem. & Drug.
1915, v. 87, p. 6738-674; Chem. Abstr. 1916, v. 10, p. 827.
IODINE ABSORPTION VALUE.
Parry, Ernest J.: The use of chloroform instead of carbon tetra-
chloride as the solvent for the oil in the determination of the iodine —
absorption value is said to be bad, as the former is lable to contain
traces of alcohol— Chem. & Drug. 1916, v. 88, No. 1913, p. 40.
Ueno. S.: An investigation of the suitability of Wijs iodine solu-—
tion for use in the determination of iodine absorption values.—Chem.
Abstr. 1916, v. 10, p. 977 from J. Chem. Ind. Japan, 1916, v. 19, p. 30. ©
Marcille, R.: A continuation of a study of the iodine number of
essential oils, with special reference to liqueurs.—Ann. Falsif. 1916,
v. 9, p. 6-11.
Backer, H. J.: A discussion of the relationship between the iodine
number and index of refraction of fats and oils. Formulas ex-
pressing this relationship are given.—Chem. Weekblad, 1916, v. 10, p.
3169.
SAPONIFICATION VALUE.
Holland, FE. B., et al.: A deseription of a method for the determina-
tion of the saponification number of fats and oils. The method is the
result of a careful study of the methods in common use.—Chem.
Abstr. 1916, v. 10, p. 1940 from Bull. Massachusetts Agric. Exper.
Sta. 1915, No. 166, p. 91-138.
Woodroffe, D.: In a note on the saponification value of oils, the
author states that 10 minutes boiling with aleoholic KOH as recom-
mended by Fahrion is insufficient for all oils. He recommends boil-
ing for one-half hour.—Chem. Abstr. 1916, v. 10, p. 1106.
6. COLOR STANDARDS AND COLORS.
Arny, H. V., and Ring, C. H.: A report of researches on color
standards and colorimetric assays—J. Ind. & Eng. Chem. 1916, v. 8,
p. 309-317.
Kelley, J. A.: An article setting forth the value of standard colors
for drug powders.—Nat. Druggist, 1916, v. 46, p. 140-141.
Angeli, B.: Color reactions and their use in qualitative analytical
chemistry.—Boll. chim.-farm. 1916, v. 55, p. 681-686.
Kress, Otto, and McNaughton, G. C.: A numerical expression for
color as given by the Ives tint photometer.—J. Ind. & Eng. Chem.
1916, v. 8, p. TL1-714.
Sammet, Frank C.: An illustrated description of a new colorim-
eter.—J. Ind. & Eng. Chem. 1916, v. 8, p. 519-521.
79
| Krais, Paul: The author presents his views on the nature of light
and color and discusses the use of the Ostwald color mixer.—Chem.
‘Zentralbl. 1916, v. 1, p. 999.
_ Harrison, W.: A discussion of the relation between the color and
the degree of dispersion of particles in colored solutions.—Chem.,
Abstr. 1916, v. 10, p.-1352.
7. ANALYTICAL METHODS AND RESULTS.
_ Lyons, A. B.: A discussion of the official method for the determina-
tion of alcohol] in pharmaceutical preparations. The process given in
the U.S. P. should be modified to the extent that the measurements,
both before and after distillation, be made at 60° F. because of the
eat variation in the coefficient of expansion for mixtures of alcohol
‘and water. The weighing could then be made at any convenient
“temperature, the percentage being computed from the official alcohol
tables—J. Am. Pharm. Assoc. 1916, v. 5, p. 807-808.
Stout, H.: Comments on the melimate analyses of the Brit. Ph.
V.—Pharm. J. 1916, v. 42, p. 190, 218, 245.
Strickland, Donald K.: Laboratory notes on the standardization of
the mercurials.—J. Ind. & Eng. Chem. 1916, v. 8, p. 253-257.
Mérner, Carl Th.: An enumeration and descriptions of reagents
and apparatus necessary for the analysis of medicinal compounds.—
Svensk farm. Tidskr. 1916, v. 20, p. 73-78.
Hackl, O.: The importance and aims of microchemistry.—Chem.
Abstr. 1916, v. 10, p. 2069.
Schneider, Albert: A discussion of the advantages and possibilities
of microanalysis, a generalization with illustrations and sugges-
tions.—Pacific Pharm. 1916, v. 10, p. 228-230, 252-254.
Grimme: A book review calls attention to a volume by S. Dezani
on the employment of microsublimation in the analysis of drugs.—
Chem. Zentralbl. 1916, v. 87, part I, p. 1044.
Phillips, S. B.: An illustrated description of a rapid method for
the estimation of fat in powders.—Analyst (The), 1916, v. 41, p.
-122-123.
- Cushny, A. R.; A paper on the analysis of living matter through
its reactions to poisons—Pharm. J. 1916, v. 97, p. 278-280.
Clarens, J.: An outline of a method for the separation of the com-
mon metals, the sulphides of which are insoluble in dilute acids.—
Ann. chim. analyt. 1916, v. 21, p. 193-196; Bull. soc. chim. France,
1916, v. 19 and 20, p. 154-158.
Muller, J. A.: A method for the analysis of mixtures containing
sulphides, hyposulphites, and alkaline dithionates.—Bull. soc. chim.
France, 1916, v. 19 and 20, p. 8-9.
80
De Fazi, R.: A description of a reaction with acenaphthene for the
detection of aldehydes.—Gaz. Chim. Ital. 1916, v. 46, p. 334-359; see
also Analyst (The), 1916, v. 41, p. 250.
Atkins, W. R. G.: Experimental data showing the application of
the method of constant boiling-point mixtures to the qualitative
analyses of certain mixed organic liquids. The experiments show
how the presence of methyl and ethyl alcohol can be detected in mix-
tures containing benzene.—Analyst, 1916, v. 41, p. 384-335.
Anon.: Recommendations for official and tentative methods of |
analysis, as presented at the annual meeting of the Association of
Official Agricultural Chemists, November 16 and 17, 1915.—J. Assoe. |
Off. Agric. Chem. 1916, v. 1, part 2, p. 1-57; v. 2, part 1, p. 59-154;
v. 2, part 2, p. 155-258, 259-381.
Kolthoff. J. M.: A discussion of various methods in use for the
titration of the hypophosphites—Pharm. Weekblad, 1916, v. 53,
p- 909-916.
De Mooij, W. J.: Observations on the utilization of the enced
mixing temperature for the quantitative determination of certain
substances.—Chem. Weekblad, 1916, v. 13, p. 608-616.
Kolthoff. I. M.: A description of methods for the determination of
the alkalinity and phosphoric acid content of the ash of foods and
condiments.—Chem. Weekblad, 1916, v. 13, p. 910-914.
Curtman, L. J., and Harris, B. R.: A procedure for the systematic —
detection of thiocyanates. The results obtained in a number of test
analyses are given to show the reliability of the method—J. Am.
Chem. Soc. 1916, v. 38, p. 2622.
Monnier, A.: Descriptions of reactions for differentiating between —
perchlorates, periodates, persulphates, percarbonates, and _per-
borates.—Ann. chim. analyt. 1916, v. 21, p. 237-240, .
Jacobson, C. A., and Holmes, A.: A description of a method for —
the separation of lauric, myristic, palmitic, and stearic acids.—J.
3iol. Chem. 1916, v. 25, p. 29-55, 55-61.
Lenher, Victor, and Truog, Emil: A report of investigations which
had for their object the improvement of the methods for the quan- —
titative determination of silica—J. Am. Chem. Soc. 1916, v. 38,
p. 1050-1063.
Monnier, A.: Notes on the employment of titanium sesquichloride |
in volumetric analysis by reduction.—Ann. chim. analyt. 1916, v. 21,
p. 109-113.
Krome, O. A.: A description of a new accurate method of gas
analysis.—J. Ind. & Eng. Chem. 1916, v. 8, p. 231-287.
For additional references on analytical methods see Chem. Abstr. :
J. Chem. Soc. Lond.; Chem, Zentralbl.; Ann. chim, analyt.
,
:
= 81
8. TESTS.
ay indecision on the part of the chemist applying any of them.
he book thus becomes a standard and may be considered an author-
y instead of being discarded, as has been frequently done, when any
slicate work was being carried on.—J. Am. Pharm. Assoc. 1917, v.
6, p. 607.
| Baty, Ernest J.: The attitude of the U. S. P. IX toward the
“law” with respect to the statement concerning the language of
chemical tests is stated to be “ innocently humorous.” The compilers
; stated to have forgotten their legal imperative in many of the
tests so that no uniformity in the matter exists—Chem. & Drug.
916, v. 88, No. 1913, p. 40.
Any, H. V.: A discussion of the tests and assay processes of the
U.S. P. 1X.—Pract. Drug. 1916, v. 34, No. 9, p. 23-25.
Beary, Ernest J.: The U. S. P. IX does not satisfy the expecta-
tions one is justified in Gidivig as to its position as a high author-
ity on the chemical matters of which it purports to treat, nor does it
attain that degree of accuracy and efficiency that is to Ke looked for
in a legal standard of chemical testing.—Chem. & Drug. 1916, v. 88,
No. 1913, p. 40.
| Merrill, E. C.: A report on the value of various resin tests —J.
Assoc. Off. Agric. Chem. 1916, v. 2, part 2, p. 82-87; see also Chem,
Kbstr. 1916, v. 10, p. 2384.
HALOGENS.
Drogin, I., and Rosanoff, M. A.: Researches on the detection and
determination of halogens in organic compounds.—J. Am. Chem.
~ Murmann, FE.: A description of a modification of the gravimetric
method for the determination of chlorine and silver. The precipi-
82
Comte: A description of a method for determining the chlori.
metric degree of the hypochlorites and their solutions.—J. pharm
et chim. 1916, v. 14, 282-233.
Anon.: A book review calls attention to the volume 8 of a iam -
book of inorganic chemistry edited by J. Newton Friend. The vol
ume treats of the halogens and their allies and is the work of Goef-
frey Martin and E. A. Dancaster—Pharm. J. 1916, v. 96, p. 79.
SULPHUR AND SULPHATES.
Blumenthal, Philip L., and Averitt, S. D.: A method for the esti
mation of thiosulphate sulphur in ese! -sulphur solution by titration
with iodine—J. Am. Chem. Soc. 1916, v. 38, p. 1701-1704.
Blumenthal, P. L., and Guernsey, S. C.: A report of an investi
gation to determine the magnitude and causes of error in the deter-
mination of sulphur as barium sulphate-—Chem. Abstr. 1916, v. 10
p. 2858.
Hutin, A.: A note on the use of acetone in the determination of
free sulphur in the sulphides of antimony, Na,SbS, and SbS,.—Ann.
chim, analyt. 1916, v. 21, p. 32-33.
Bartells, G. C., and Brandt, C. E.: A method for the determina-
tion of sulphur in plant foliage is described. The results obtained
in a number of analyses are also given.—Chem. Abstr. 1916, v. 10,
p. 449, from Bull. Bur. Mines, 1915, No. 98, p. 297-300. a
Dr ial J. C.: Volumetric reeeode for the estimation of total |
sulphur and sulphates in small quantities of urine are described.—
Biochem. J. 1915, v. 9, p. 492-507; Chem. Abstr. 1916, v. 10, p. 1359
Levi, L. E., and Orthmann, A. C.: The authors describe in detail a
method for the determination of total sulphates in leather.—Chem.
Abstr. 1916, v. 10. p. 2811.
PHOSPHORUS AND PHOSPHATES,
Lemkes, H. J.: A discussion of experimental data obtained in the
detection of phosphorus according to the method of Van Dusart and
Blondlot, and of the application of the method to toxicological work.
Pharm. Weekblad, 1916, v. 53, p. 1496-1513.
Christie, A. W.: A report of experiments with the MgO method
for the determination of total phosphorus in plant materials.—J.
Ind. & Eng. Chem. 1916, v. 8, p. 511.
Hicks, W. B.: The author describes several simple tests for phos-
phates in minerals.—Chem. Abstr. 1916, v. 10, p. 3046. 5
Howland, John, et al.: Notes on the use of Fe(SCN), in the mi-
crocolorimetric determination of inorganic phosphates in the blood
serum.—J. Biol. Chem. 1916, v. 24, p. 18-19.
83
_ Arny, H. V., and Ring, C. H. Detailed descriptions of colori-
metric methods for the determination of phosphates are presented in
an article dealing with colorimetric standards and assays.—J. Ind. &
Eng. Chem. 1916, v. 8, p. 309-317.
Z Jones, Walter: A ee of the admissibility of ammonium
magnesium phosphate as a form in which to weigh phosphoric acid
in its quantitative determination.—J. Biol. hace 1916, v. 25, p.
87-91.
- Crispo, D. “s and Tuinzing, R. W.: Notes on the estimation of phos-
phoric acid in fertilizers by the citro-uranium method.—J. Chem.
‘Soc. 1916, v. 110, p. 342.
NITROGEN, NITRATES, AND NITRITES.
- Justin-Mueller, Ed.: Total nitrogen—a practical and accurate
method for the volumetric determination of the ammonia formed in
the destruction of organic matter in the presence of mercury.—Bull.
se. pharmacol. 1916, v. 23, p. 167-169.
Phelps, I. K., and Daudt, H. W.: An investigation of the Kjeldah
method for estimating nitrogen. A study of various conditions of
digestion was made on pyridine zinc chloride.—J. Biol. Chem. 1916
vy. 24, p. 35.
Cope, W. C.: A modification of the Kjeldahl method for the deter-
mination of nitrogen in nitro substitution compounds.—J. Ind. &
Eng. Chem. 1916, v. 8, p. 592-593.
_ Latshaw, W. L.: A note cn sodium sulphate as a substitute for
potassium sulphate in the Gunning modifications for determining
nitrogen.—J. Ind. & Eng. Chem. 1916, v. 8, p. 586-587.
Bowman, Fred C., and Scott, W. W.: A report of investigations
relative to the titration of nitrates with ferrous sulphate-—Chem.
News, 1916, v. 114, p. 39-41.
Scales, F. M.: An illustrated description of a method for the deter-
mination of nitric nitrogen.—J. Biol. Chem. 1916, v. 27, p. 327-337.
_ Davisson, B. S.: A titrametric method for the determination of ni-
trites. Experimental data obtained by the use of the method are also
‘presented.—J. Am. Chem. Soc. 1916, v. 38, p. 1683-1687,
’
CARBON AND CARBONATES,
Waggaman, W. H.: 53 Seah ae of a rapid method for the deter-
inatl . & Eng. Chem. 1916, v. 8, p. 41
Le Chatelier, H., a ta actich: F.: A note on the determination
of carbon by the method of Eggertz.—Compt. rend. acad. sc, 1916, v.
162, p. 709-714.
84
Fisceman, G.: Descriptions of modifications of the Pregl micro
chemical method for the estimation of carbon and hydrogen.—J.
Chem. Soc. Lond. 1916, v. 110, part 2, p. 645-646. __
Rinkes, I. J.: A ee iption of J. V. Dubsky’s microchemical mothe
ods for the quantitative determination of carbon, hy drogen, and ni-
trogen.—Chem. Weekblad, 1916, v. 13, p. 800-803. |
Robertson, Philip W.: Researches on the simultaneous estimation
of carbon and halogen by the chromic acid method—QJ. Chem. Soc.
Lond. 1916, v. 109, p. 215-221.
Grignard, V., and Abelmann, A.: An illustrated description of a
method for the determination of carbon, hydrogen, and mercury in or-
ganomercuric compounds.—Bull. soc. chim. 1916, v. 19, p. 25-27.
Cavazzi, A.: A method for the determination of carbon dioxide in
carbonate decomposed by solutions of ammonium chloride is de-
scribed. The method is based on the fact that small amounts of the
finely powdered carbonates of the alkali metals, alkaline earth metals,
and Zn, Pb, Cd, Bi, and Cu are decomposed and dissolved in solu-
tions = ammonium chloride—Ann. chim. applicata, 1915, v. = p-
137-144.
ALKALI COMPOUNDS.
Kolthoff, I. M.: A method for the simultaneous determination of —
the alkalinity and phosphoric acid content of the ash of foodstuffs is
described.—Chem. Weekblad, 1916, v. 13, p. 910-914.
Newington, F. H.: A method for the quantitative determination —
of the free caustic alkali in soap is described.—J. Soc. Chem. Ind.
1916, v. 35, p. 95-96.
Sacher, J. F.: Notes on the use of a neutral soap solution as an
indicator in the determination of the alkali content of solutions of —
organic colors.—Chem. Abstr. 1916, v. 10, p. 866.
Hicks, W. B.: Simple tests for potash'in rocks and soils are. de-
scribed.—Chem. Abstr. 1916, v. 10, p. 2444.
Hager, G., and Kern, J.: Notes on the estimation of potassium
in potassium salts by the perchlorate method.—J. Chem. Soc. Lond..
IDLO, 110, sp. 4:
Jarrel, T. D. A report on the effect of using denatured alcohol for
washing the K.,PtCl, precipitate, the necessity for using hydrochloric
acid in the aqueous extract and on the perchlorate method for de-
termining potassium.—J. Assoc. Off. Agric. Chem. 1915, v. 1, p.
400-411; Chem. Abstr. 1916, v. 10, p. 244.
Bennett, Alex. H.: A description of a method for the estimation
of potassium in the presence of other substances.—Analyst (The),
1916, v. 41, p. 165-168.
Palkin, S.: A description of a method for the separation of lithium |
from the other alkali metals—J. Am. Chem. Soc. 1916, v. 38, p. 2826.
85
ALKALINE EARTH COMPOUNDS.
pounds.—J. Am. Pharm. Assoc. 1916, v. 5, p. 415.
_ dodidi, S$. L., and Kellogg, E. H.: Analytical data bearing on
application of the paper pulp filter to the quantitative estima-
tion of calcium and magnesium.—J. Franklin Institute, 1916, v.
81, p. 217-232; see also Chem. Eng. 1916, v. 23, p. 60-65.
| Raikow, P. N.: A description of a method for the detection of
fealcium in the presence of barium and strontium depends on the
ct that calcium carbonate is decomposed at temperatures between
0 and 900° C., whereas the barium and strontium compounds re-
- Winter, O. B.: A modificatioa of McCrudden’s method for cal-
cium, for the estimation of calcium and strontium in the presence of
a smal] amount of iron and phosphoric acid.—J. Ind. & Eng. Chem.
1916, v. 8, p. 603-604.
Cahen, Edward, and Hurtley, William H.: A description of a
‘method for the estimation of calcium in organic materials.—Bio-
2: J. 1916, v. 10, p. 308-312.
~ de Coninck, W. O.: A discussion of some reactions of the car-
bonates of calcium, strontium, magnesium, and zine.—Ann. chim.
analyt. 1916, v. 21, p. 131- 133.
ANTIMONY AND ARSENIC.
_ Fleury, E.: A brief note on the detection of arsenic in the purga-
_tive sulphates.—J. pharm. et chim. 1916, v. 13, p. 85.
- Carles, P.: Notes on the detection of arsenic in official sodium
sulphate.—Repert. pharm. 1916, v. 28, p. 130-151; see also Chem.
wAbstr. 1916, v. 10, p. 1905.
Schneider, Albert: A description of a biological test for arsenic
~which has been used for some time in Germany and other European
countries. Penicillium brevicaule is the organism used.—Pract.
Drug. 1916, v. 34, No. 2, p. 32.
’ Hibbert, John C.: An illustrated description of an improved ap-
_ paratus op the detection and estimation of arsenic by the Gutzeit
method. —J. Soc. Chem. Ind. 1916, v. 35, p. 672-673.
~ Curtman, L. J., and Daschavsky, P.: A study of the silver arsenate
test for arsenic_—J. Am. Chem. Soc. 1916, v. 38, p. 1280-1282.
- Ewins, Arthur J.: A description of a method for the estimation
of arsenic in organic compounds. The organic material is: decom-
| posed by digestion with potassium sulphate, starch, and sulphuric
86
acid. The arsenic is finally titrated by means of N/20 iodine solu-
tion.—J. Chem. Soc. Lond. 1916, v. 109, part 2, p. 1855-1358.
Meillére, G.: From experiments, it is concluded that the hair i
the best source for detecting arsenic in industrial workers.
method for carrying out the test is described.—J. pharm. et chim
1916, v. 14, p. 5-7.
Roark, R. C., and McDonnell, C. C.: Researches on the reduction
of pentavalent arsenic to trivalent arsenic by cuprous chloride and
the determination of arsenic by distillation as arsenic trichloride.—
J. Ind. & Eng. Chem. 1916, v. 8, p. 327-881.
Browning, Philip E., et al.: Notes on the qualitative separation
and detection of arsenic and tellurium.—Am. J. Se. 1916, v. 41, p.
106-108.
Peters, C. A., and Fielding, L. E.: An outline of an oxalate-iodide
process for the analysis of Paris green—J. Ind. & Eng. Chem. 1916,
¥, 8 ps114—1145.
Vaubel, W., and Knocke, A.: Notes on the behavior of antiaall
stains or deposits toward hypochlorite solution.—Chem. Zeit. 1916,
v. 640, p. 209-210 through Analyst (The), 1916, v. 41, p. 147.
METALS.
Doring, Th.: A review of the advances in the field of metal analy-
sis during the year of 1915. <A bibliography is appended.—Chem.
Zte. 1916, v. 40, p. 817-818, 830-831, and 855-858. |
Murray, B. L.: A description of an electrolytic method for the
determination of bismuth-betanaphthol mixtures.—J. Ind. & Eng.
Chem. 1916, v. 8, p. 257.
Mayer, Peek L.: A description of a eolamimeeete method for the
estimation of iron in pharmaceutical preparations.—J. Am. Pharm.
Assoc. 1916, v. 5, p. 517-519.
Minovici and Grozea, Em.: A description of the action of salts of ©
mercury upon aluminum foil, with suggestions for the application —
of this reaction in the detection of mercury salts in general or toxi-
cological analysis. An abstract.—J. pharm. et chim. 1916, v. 13, p.
358-359. j
Vanderkleed, C. E., and E’we, G. E.: A description of a method
for the quantitative determination of potassium in colloidal silver —
preparations.—J. Am. Pharm. Assoc. 1916, v. 5, p. 715.
Wastenson, Hugo: A comparison of methods for the determination
of silver in organic preparations of silver, such as protargol, largin,
novargan, albargin, collargol, etc.—Pharm. Post, 1916, v. 41, p.
187-188.
Blum, William: A report of experimental work on the determina-
tion of aluminum as oxide.—Bull. Bur. Stand. 1916, v. 13, No. 4, p.
515-534; J. Am. Chem. Soc. 1916, v. 38, p. 1282-1297,
od 87
4 _ Sidener, C. F., and Pettijohn, Earl: Notes on the determination
of aluminum as acinam hydroxide.—J. Ind. & Eng. Chem, 1916,
é y. 8, p. 714-716.
be - Schoch, Eugene P., and Ruy n, Denton J.: A description of an
- electro-analytical method for the determination and Spa. of
* the metals of the copper-tin group.—J. Am. Chem. Soe. 1916, v. 38,
_ p. 1660-1681.
: Waddell, John: A description of a new volumetric method for the
~ estimation ns lead.—Analyst (The), 1916, v. 41, p. 270-272.
Ivanow: A note on the use of a 2 per cent solution of sodium bisul-
| Phite as a reagent for the detection, of lead.—Repert. pharm. 1916
vy. 28, part 1, p. 233-234.
& Bertisian, G.: A description of a rapid method for the determina-
F tion of eed J. Ind. & Eng. Chem. 1916, v. 10, p. 331.
[ Hallett, R. L.: A report of researches dealing with the volumetric
_ determination of tin—J. Soc. Chem. Ind. 1916, v. 35, p. 1087-1089.
Chancel, F.: A description of an electrolytic method for the quan-
_ titative determination of zinc—Bull. soc. chim. France, 1916, v. 19°
and 20, p. 59-63.
_ $Szasz, Ernest: A description of a rapid method for the determina-
_ tion of manganese.—Chem.-Ztg. 1916, v. 40, p. 810-811.
Schoeller, W. R., and Powell, A. R.: The alkalimetric estimation of
certain divalent metals in the form of tertiary phosphates, with spe-
cial reference to the volumetric determination of cobalt and nickel.—
) Analyst (The), 1916, v. 41, p. 124-138.
_ Edgar, Graham: A rapid method for the estimation of copper and
- iron.—J. Am. Chem. Soc. 1916, v. 38, p. 884-887.
_ Middleton, A. R., and Miller, H. L.: Researches on the detection of
~ mekel in cobalt salts—J. Am. Chem. Soc. 1916, v. 38, p. 1705-1711.
Engle, W. D., and Gustavson, R. G.: An outline of the new volu-
metric method for the determination of cobalt.—J. Ind. & Eng. Chem:
1916, v. 8, p. 901-902.
y)
ORGANIC COMPOUNDS.
Dubsky, J. D.: An illustrated description of a simple quantitative
method for the microelementary analysis of organic substances.—
_ Chem.-Ztg. 1916, v. 40, p. 201-203,
Grignard and danirianw: A.: A description of a new procedure
for the simultaneous determination of carbon, hydrogen, and mercury
in organic compounds containing mercury.—Bull. soc. chim. France,
1916, v. 19 and 20, p. 25-27.
Fisher, Harry L.: An illustrated description of a new form of
_ absorption bottle for use with either calcium chloride or soda lime
in the elemental analysis of carbon and hydrogen in organic sub-
_ stances.—J. Ind. & Eng. Chem. 1916, v. 8, p. 368-369,
88
De Fazi, R.: A description of a new reaction for distinguishing
between alaphatic and aromatic aldehydes.—Gaz. Chim. Ital. 1916,
y. 46, p. 334-359. .
Belfit, Robert W.: A descripticn of a method for the direct ae
termination of rubber in rubber compounds.—J. Ind. & Eng. Chem.
1916, v. 8, p. 826-827.
; SUGARS,
Kolthoff, I, M.: A study of a number of solutions in an attempt to
discover the most sensitive reagent for detecting fructose in the pres-
ence of aldoses, particularly glucose-—Chem. Weekblad, 1916, v. 13,
p- 887-895. Y
Adanti, G.: A description of an indirect method for the quantita-
tive determination of certain sugars.—Boll. chim.-farm. 1916, y. 55,
p. 33-35,
Wilson, Edith G., and Atkins, William R. G.:-The estimation of
reducing sugars by Kendall’s solution and the construction of a table
indicating the reducing power of levulose——Biochem. J. 1916, v.
10, p. 137-141. |
Davis, W. A.: Experimental data on the use of enzymes and spe-
cial yeasts in the analysis of sugars—J. Soc. Chem. Ind. 1916, v. 35,
p. 201-210, |
van der Haar, A. W.: A description of a method for the quanti-
tative estimation of free and combined nealneneee: —Chem. Weekblad,
1916, v. 13, p. 1204-1213.
Schaffer, F.: A colorimetric method for the determination of pen- |
toses and methylpentoses in wine is described.—Chem. Abstr. 1916,
v. 10, p. 1248 from Mitt. Lebens. Hyg. 1915, v. 6, p. 163-167.
von Fellenberg, 'T.: The author describes the adaptation of his
methods for condensed milk to the estimation of lactose and sucrose
in milk chocolate-——Chem. Abstr. 1916, v. 10, p. 1769.
Pellet, H.: A discussion of methods for the determination of rafli-
nose in the presence of sucrose. The yeast method is stated to have
given good results in the hands of several analysts—Ann. chim.
analyt. 1916, v. 21, p. 89-91.
9. DIAGNOSTICAL REAGENTS AND CLINICAL TESTS.
Beringer, George M.: The chapter on diagnostical reagents and —
clinical tests is an important addition to the U. S. P., in which the
example of the later revisions of some of the foreign pharmacopeeias,
notably the German pharmacopcia, is followed—Am. Druggist,
1916, v. 64, No. 8, p. 24.
Niece, Frederic E.: The diverse findings frequently revealed in
clinical laboratory reports are so conflicting that criticism has been
made thereon and the need for more uniformity in the methods has
89
been advocated. The U.S. P. now includes a number of reagents for
Clinical tests from which a set of standard methods might be de-
' veloped.—J. Am. Pharm. Assoc. 1916, v. 5, p. 837-840.
_ Lackenbach, Fred I.: A short general discussion of the subject of
routine clinical laboratory tests. The paper includes descriptions of
§ a number of.tests and points out their significance.—J. Am. Pharm.
' Assoc. 1916, v. 5, p. 17-20. ;
_ Stewart, F. E.: A lecture on diagnostic reagents and their uses in
| | the diagnosis of infectious diseases.—J. Am. Pharm, Assoc. 1916,
_ y. 5, p. 975-982, 1196-1201, 1310-1322,
s _ Dunning, H. A. B.: In discussing the phenolsulphonephthalein test
_ for renal functionation, the author states that it is now almost uni-
_ yersally considered by broad-minded medical men that, for ascertain-
| *ing the eliminating power of the two kidneys or the special function
_ of either kidney, the ideal reagent is closely approached by phenol-
| sulphonephthalein— J. Am. Pharm. Assoc. 1916, v. 5, p. 268-271.
- Brown, Philip K., and Cummins, W. I.: A study of the etiology
of chronic nephritis and of the efficiency of the phenolsulphoneph-
- thalein test—J. Am. M. Assoc. 1916, v. 66, p. 793-797.
_ Anon.: Observations on the use of the colloidal solution of gold in
_ the diagnosis of syphilis.—J. pharm, et chim, 1916, v. 13, p. 294-295
from Pharmazevtizeski J. 1916, p. 92.
- Anon.: A review of recent researches on the urine, feces, and dis-
- charges.—J. pharm. et chim. 1916, v, 18, p. 294-295.
Ito, Hiizu: A method for the quantitative determination of hyp-
) puric acid in urine, blood, muscle, and liver.—J. Am. Chém. Soc,
~ 1916, v. 38, p. 2188-2192.
—
URINE.
Steffens, John A.: A discussion of the manner in which specimens
of urine should be taken for analysis—C. U. C. P. Alumni J. 1916,
v. 23, p. 23-24.
Anon.: An enumeration of medicinal substances which, upon ab-
sorption, affect the normal properties of urine.—J. pharm. et chim.
1916, v. 14, p. 57-58; see also Chem. Abstr. 1916, v. 10, p. 1046.
) _ Strickrodt, A.: A review of the results of investigations on urine
constituents during the year 1915.—Chem. Abstr. 1916, v. 10, p. 2098
from Ber. pharm. Ges. 1916, v. 26, p. 49-72.
Anon.: -A book review calls attention to a small volume by Chas.
C. Yarbrough entitled Hints in Practical Urinalysis—Pharm. Era,
1916, v. 49, p. 211.
Petzetakis: A description of an iodo reaction which serves for the
identification of pathological urine—Yearbook of Pharmacy, 1917,
p. 46 from M. Press, 1916, v. 102, p. 464.
90
Lipp, Hans: A description of a simplified method for coloring
urine sediments.—Siidd. Apoth.-Ztg. 1916, v. 56, p. 491.
Fittipaldi: A description of a differential stain for the sediment in
urine.—J. Am. M. Assoe. 1916, v. 66, p. 231 from Gazz. Ospedal, 1915,
y. 36, p. 1265.
Binda, P.: A note on the presence of scatol in the distillate ob-
tained from urine. The presence of scatol is thought to possess
clinical significance-——Chem. Abstr. 1916, v. 10, p. 630 from Gaz.
Med. Ital. v. 64, p. 801-302.
Anon.: An editorial discussing the significance of nitrates in the
human urine.—J. Am. M. Assoc. 1916, v. 67, p. 122.
Bang, Ivar: Data showing the amount of arsenic present in nor-
mal urine.—Physiol. Abstr. 1916, v. 1, p. 244.
McCrudden, F. H., and Sargent, C. F.: Researches on the occur- /
rence and determination of creatine in the urine——J. Biol. Chem.
1916, v. 24, p. 423-429.
Gallois and Mouchel: A description of a method for the identifica-
tion of cryogenine in the urine—J. pharm. et chim. 1916, v. 13, p.
372-377.
Justin-Mueller, Ed.: A description of an abnormal yellow pigment —
in the urine. The pigment resembles cryogenine in some of its prop- —
erties.—J. pharm. et chim. 1916, v. 14, p. 199-201.
Anderson, R. J.: A report on the isolation of a nonphenolic vola-
tile oil from the urine of the horse and of man.—J. Biol. Chem. 1916,
y. 26, p. 409-415.
Marshall, J. T. W., Banks, H. W., and Graves, S. S.: A comparison
of gravimetric and nephelometric methods for the estimation of
proteins in urine.—Arch. Int. Med. 1916, v. 18, p. 250-262.
Gradwhol, R. B. H., and Blaivas, A. J.: A description of a simple
method for the determination of nitrogen in urine.—J. Am. M.
Assoc. 1916, v. 67, p. 809.
Dohmmée, R.: A description of a method for the determination of
the total nitrogen in urine.—Bull. se. pharmacol. 1916, v. 128, p. 68.
Krogh, Marie: A description of a clinical method for the determi-
nation of nitrogen in urine. Nitrogen is liberated from 1 cubic
centimeter of the day’s urine by the hypobromite method of the
author, and the total nitrogen is arrived at by a series of computa-
tions.—Physiol. Abstr. 1916, v. 1, p. 361.
Hollande, A. Ch.: A report of investigations on the detection of
caffeine in the urine.—J. pharm. et chim. 1916, v. 14, p. 324-326.
Schering: A description of a method for the detection of urotro-
pine in urine.—Boll. chim.-farm, 1916, v. 55, p. 328.
¥drac: Notes on the detection of picric acid by means of the for-
mation of potassium isopurpurate, and the application of this re-
action to the determination of picrie acid in urine.—Bull. se. phar-
91
_ Grimbert, L.: A lecture on the methods of determining picric acid
in the urine.—J. pharm. et chim. 1916, v. 13, p. 177-190.
| Grélot, P.: On the coexistence of picric and picramic acids in tho
pt urine after the ingestion of picric acid—Bull. sc. pharmacol. 1916,
" y. 23, p. 65-67; see also Chem. Abstr. 1916, v. 10, p. 1991.
» Barral, Et.: a discussion of methods for the iabibon of picramic
acid from urine and for its identification—Ann. Falsif. 1916, v.
9, p. 231-244.
ig Pecker, Henri: Notes on the diazo reaction for the detection of
_ picramic acid in the urine—Compt. rend. soc. biol. 1916, v. 79, p.
— 139-140.
_ Mareck, Richard: Bib eauatiate on the diagnostic value of tho
urochromogen test (Weiss) in typhoid fever.—Chem. Zentralbl.
/ 1916, v. 2, p. 524.
_ Burgess, Alexander N.: A report of investigations relative to tho
_ urochromogen reaction as an aid to prognosis in pulmonary tuber-
_culosis and nontuberculous disease.—J. Am. M. Assoc. 1916, v. 66,
p. 82-85; see also Sinclair, p. 247-248; Cowen, p. 791-793.
~ Wellwart, N.: A note on a color reaction obtained with urine from
patients suffering from cancer of the stomach.—Chem. Abstr. 1916,
vy. 10, p. 1671, from Miinch. med. Wehnschr. 1916, v. 63, p. 311.
Cowen, M. E.: From phy sicians’ findings, the conclusions are tha’
_ the positive urochromogen reaction in patients with pulmonary tu-
_ berculosis results only when there is an actual destructive proces;
ie going on. Occurring in an ambulant case, we would regard it as a
_ warning that the patient should be put at absolute rest in bed—
J. Am. M. Assoc. 1916, v. 66, p. 791-793.
ACIDITY.
Anon.: An outline of Folin’s method for the titration of the acid-
ity of the urine.—J. Am. M. Assoc. 1916, v. 66, p. 978.
Kolthoff, J. M.: A presentation of analytical data relative to th»
_ acidity of urine, with notes on the oxidation of urine with potassiuni
permanganate.—Pharm. Weekblad, 1916, v. 53, p. 896-405,
Hartley; W. H.: A description of a test for the presence of diacetic
_ acid in urine.—Schweiz. Apoth.-Ztg. 1916, v. 54, p. 341.
Rosenbloom, Jacob: A description of a modification of Gerhardt’s
test for diacetic acid in urine.-—Biochem. Bull. 1916, v. 5, p. 25.
ACETONE.
Sammet, O.: A discussion of the merits and disadvantages of th»
more common methods for the detection of acetone in urine.—
Schweiz, Apoth.-Ztg. 1916, v. 54, p. 177-180.
92
Csonka, F. A.: A description of a colorimetric method for estimat-
ing acetone in urine. The method is based on the red color of the
alkaline salt of dioxydibenzene acetone.—J. Biol. Chem. 1916, v. 27,
p. 209-212.
Granell, Conrado: A rapid method for the determination of ace-
tone in the urine.—Iarm. Espan. 1916, v. 48, p. 185-137.
Lenk, Emil: Descriptions of methods for the quantitative deter-
mination of acetone substances in the urine.—Biochem. Ztschr. 1916,
v. (8, p. 224-2380.
ALBUMIN.
Dhommée, René: A general discussion of the various methods
which have been proposed for the quantitative estimation of albu-
min in urine with a description of a new method evolved by the
author. A solution of picric acid, with trichloracetic acid or with
trichloracetic and citric acids, is employed as the reagent for pre-
cipitating the albumin.—J. pharm. et chim. 1916, v. 138, p. 241-249;
see also Bull. se. pharmacol. 1916, v. 23, p. 160-167.
Gonassini, Domenico: Researches on the determination of albu-
min in urine.—Bull. chim.-farm. 1916, v. 55, p. 260-263,
Godfrin, P.: A criticism of the heat mead for detecting the
presence of albumin in urine, and a description of a new process
permitting the detection of the smallest trace of albumin.—J. pharm.
et chim. 1916, v. 14, p. 294-303.
Wolter: Notes on the nitric acid test for albumin. A reply to
criticisms offered by Droste—Pharm. Zentralh. 1916, v. 57, p. 13.
Jones, H. E.: A note on a source of error in Esbach’s albumino-
meter. Esbach’s reagent does not precipitate all of the albumin in
alkaline urine.—Physiol. Abstr. 1916, v. 1, p. 109.
Liebers: A note on the use of a 10 per cent solution of phenol as a
reagent for the detection of albumin in urine.—Chem. Abstr. 1916, —
v. 10, p. 1654 from Deutsch, med. Wehnschr. 1916, v. 42, p. 323.
Sueyoshi, Y.: A description of an improved techique for the phos-
photungstate test for albumin. An abstract.—J. Am. M. Assoc.
1916, v. 66, p. 929.
Siebers: A description of a new precipitation test for the detec-
tion of albumin in urine.—Schweiz. Apoth.-Ztg. 1916, v. 54, p. 474.
Gaillard: A report of a case in which the urine gave a reaction
for ovalbumin when tested with Maurel’s reagent. It was definitely
proven that ovalbumin was not present, hence the reaction with
Maurel’s reagent is not a reliable test for this substance.—J. pharm.
et chim. 1916, v. 14, p. 321-322.
Godfrin, P.: A report of an abnormal case of albuminuria. A
part of the albumin was precipitated by sodium sulphate only in
the presence of acetic acid.—J. pharm. et chim. 1916, vy. 13, p. 249-254.
93 .
_ Hollande, A. Ch. et al: A description of a method for the detec-
tion of egg albumen in urine in cases of simulated albuminuria.—
Ann. Falsif. 1916, v. 9, p. 73-74.
_ Godfrin, P.: A description of a new process for the ready detec-
albumin is completely precipitated by saturation with sodium chlor-
ide in the presence of a-slight excess of acetic acid, while ovalbumin
ds net.—J. pharm. et chim. 1916, v. 14, p. 257-260; see also p. 830,
AMMONIA,
Scheltema, M. W.: The determination of the ammonia of amino
ik ids and albumin in urine by means of formaldehyde—Pharm.
Weekblad, 1915, v. 52, p. 1549-1555; see also Chem. Abstr. 1916, v.
DeGraaf, W. C., and van der Zande, J. E.: A discussion of the
methods for the determination of ammonia and amino acids.—
geharm. Weekblad, 1916, v. 53, p. 1378-1382,
BILE.
Edelmann, A.: A description of a clinical method for detecting
‘urobilin in urine or feces——Chem. Abstr. 1916, v. 10, p. 2098 from
Wien. klin. Wehnsehr. 1915, v. 28, p. 978-979.
aes oe
.
BLOOD,
_ Knack, A. V.: The use of benzidine tablets for the performance of
| Adler’s test for blood in urine is recommended.—Physiol. Abstr.
11916, v. 1, p. 248.
: Domenat, eA. description of a new method for the determina-
_ tion of the presence of blood in fluids——Physiol. Abstr. 1916, v. 1,
> p. 296.
Kuh: A description of a test for blood in urine based on the color
reaction with guaiaconic acid.—Schweiz. Apoth.-Ztg. 1916, v. 54,
p. 475.
CHLORIDES.
'. Seelman, J. J.: A description of a simple test for estimating
ra _ chlorides in the urine founded on Volhard’s method.—J. Lab. & Clin.
_ Med. 1916, v. 1, p. 444-445.
3 INDICAN,
__ Justin-Mueller, Ed.: A study of indoxyl from urine, including a
description of the methods of isolating and quantitatively determin-
ing the same.—Bull. sc. pharmacol. 1916, v, 23, p. 85-92,
94 a
SUGAR.
Anon.: A list of the mistakes frequently made in the examination
of urine, more particularly in the detection of sugar or in the use o
Fehling’s reagent.—Sudd. Apoth.-Ztg. 1916, v. 56, p. 49.
Liebers: Notes on the employment of methylene blue for the detec-
tion of sugar in urine.—Deutsch. med. Wchnschr, 1916, v. 42, p.
1197-1198.
Baker, Julian N., and Hulton, I. F.: A déscription of a method
for the estimation of pentoses and of pentesans by means of Fehl-
ing’s solution.—Analyst, 1916, v. 41, p. 294-297.
Myers, V. C.: A description of a method for the determination of
small amounts of stgar.—Proc. Soc. Exper. Biol. 1916, v. 13, p.
178-180. }
Frerichs, G., and Mannheim, E.: A description of a method for
the determination of d-glucose in urine.—Schweiz. Apoth.-Ztg. 1916,
v. 54, p. 474.
UREA.
Editorial: The comparative physiology of urea formation. <A re- —
view.—J. Am. M. Assoc. 1916, v. 67, p. 817.
Tbanes, Modeste Maestre: Notes on the employment of soluble fer-
ments for the quantitative determination of urea.——J. pharm. et chim.
1916, v. 13, p. 259-262 from Ann. de la Soc. espan. de phys. et chim.
1916, p. 88.
Dunning, H.-A. B.: A discussion of the methods of using urease
and for calculating the urea content.—J. Am. Pharm. Assoc. 1916,
y. 5, p. 809-811.
Ww hite, J. S., and Williams, I. G.: Comments on the Betedies and
the urase methods for the estimation of urea in urine.—Pharm.
J. Be v. 96, p. 323.
Van Sly ke, Donald D., and Cullen, Gea E.: Descriptions of
amplifications of eertain points in the technique of the urease method
for the estimation of urea.—J. Biol. Chem. 1916, v. 24, p. 117-122.
Mom, C. P.: On the utilization of Urobacillus Pasteurti for the
quantitativ e determination of urea in urine.—Chem. Weekblad, 1916,
v. 13, p. 72-75, 255-257,
URIC ACID.
Curtman, L. J., and Freed, M.: A description of a modified Bene-
dict and Hitcheock uric acid standard solution for use in cold
weather.—J. Biol. Chem. 1916, v. 28, p. 89-92.
CAMMIDGE REACTION,
van Hoogenhuyze, C. J. C., and Magasaki, S.: A report of re-
searches to determine the influence of food on the Cammidge re-
action.—Physiol. Abstr. 1916, v. 1, p. 226.
95
FECES.
_ Laws, C. H., and Bloor: A description of a method for the estima-
on of fat in feces by means of the nephelometer.—J. Am. M. Assoc.
1916, v. 66, p. 916.
Donaldson, R., and Meieloaiy R. C.: Illustrated descriptions of
a number of plant hairs are given for the purpose of preventing
their being mistaken for parasites in the examination of feces.—
eencet, 1916, v. 191, p. 1100.
- Krauss, Ludwig: A description of a method for the detection of
"occult blood in feces—Sudd. Apoth.-Ztg. 1916, v. 56, p. 72.
Snapper: A description of a method for the spectroscopic detec-
“tion of blood in feces. The method is stated to be as sensitive as the
benzidine test—Physiol. Abstr..1916, v. 1, p. 531.
Tonney, F. O., et al.: Investigations relative to the examination
_ of the urine and feces of suspect typhoid carriers, with a report on
elaterin catharsis.—J. Infec. Dis. 1916, v. 18, p. 239-246.
GASTRIC CONTENTS.
Elbridge, J. B.: A description of a fractional method for the ex-
amination of the stomach contents. A number of charts are pre-
sented.—J. Am. M. Assoc. 1916, v. 67, p. 1083-1086.
Sheaff, Philip Atlee: An aspirating apparatus for office and hos-
pital use in obtaining gastric contents. Illustrated —J. Am. M.
Assoc. 1916, v. 67, p. 875.
_ Pron, L.: Researches relative to the biuret reaction in the patho-
_ logical stomach during fast, and in the absence of alimentary resi-
~ dues.—Compt. rend. soc. biol. 1916, v. 79, p. 68-69.
Friedenwald, Julius, and Kieffer, Richard: A discussion of the
value of the quantitative determination of dissolved albumin in the
gastric contents in the diagnosis of cancer of the stomach.—Am. J.
M. Se. 1916, v. 152, p. 321.
SPUTUM.
Bers, H.: A new method for the detection of tubercle baccilli
in sputum.—Compt. rend. acad. sc. 1916, v. 163, p. 111.
Giraud, N., and Derrien, E.: A note on the use of pyridine for
‘rendering the sputa fluid in demonstrating tubercle bacilli—Compt.
_ rend. soc. biol. 1916, v. 79, p. 976-977.
BLOOD.
De Dominicis, Angelo: A new method for the identification of
human blood.—Boll. chim.-farm. 1916, v. 55, p, 513-514.
‘Benedict, A. L.: A discussion of the subject of blood examinations
by the J. Clin. Med. 1916, +. 23,
- p. 997-1000.
Be
96
J. A.: A discussion of new methods for the quantitive examina-
tion of blood.—Schweiz. Apoth.-Ztg. 1916, vy. 54, p. 541-548, 557-559,
Gettler, A. O., and Baker, Willis: Data obtained in the physical
and chemical analysis of blood in 30 normal cases.—J. Biol. Chem.
1916, v. 25 p. 211-293.
Josué, O., and Parturier, Maurice: A report of researches on the
viscosity of human blood.—Compt. rend. soc. biol. 1916, v. 79, p. 371—
381.
Lyon, Marcus W.: A description of a simple method for estimat-
ing the coagulation time of blood—ZJ. Am. M. Assoc. 1916, v. 66,
p. 891.
W. C. De G.: A review of a small pamphlet by Ivar Bang oa ™
microanalytical methods for the determination of some of the con-—
stituents of the blood——Chem. Weekblad, 1916, v. 13, p. 599.
Editorial: Descriptions of methods for the determination of
glucose in the blood.—J. Lab. and Clin. Med. 1916, v. 1, p. 252-256.
Hirsch, Ernst: Experimental data showing the sugar content of
human blood under physiological and pathological conditions when
determined by Bang’s micro method.—Physiol. Abstr. 1916, v. 1,
p- 805.
McDanell, Louise: Notes on the estimation of sugar in the blood —
by the Lewis-Benedict method, with a graph for obtaining directly
the percentage of dextrose—J. Lab. & Clin. Med. 1916, v. 1, p. 804
808.
Myers, Victor C., and Bailey, Cameron V.: The Lewis and Bene-
dict method for the estimation of blood sugar, with some observa-
tions made in disease.—J. Biol. Chem. 1916, v. 24, p. 147-161.
Macleod, J. J. R.: A description of a rapid and accurate clinical
method for the estimation of sugar in small quantities of blood.—J.
Lab. & Clin. Med, 1916, v. 1, p. 445-446.
Kuttner, Theodore: A discussion of various methods for the esti-
mation of hemoglobin, with a description of a modified Sahli-Gower
method.—J. Am. M. Assoc. 1916, v. 66, p. 1370-1373.
Haessler, H., and Newcomer, H. 8.: A description of a clinical
hemoglobinometer. The apparatus is a colorimeter on Sahli’s
principle, with numerous standard tubes.—Arch. Int. Med. 1914, -
v. 17, p. 806-808.
Schumm, O.: A report of researches showing the cases in which
hematin is a pathological constituent of the blood. An abstract.—J,
Chem. Soc. Lond. 1916, v. 110, part 1, p. 775.
Combe and Meyer-Lévyi: A description of a method for the
quantitative determination of urea in blood.—Répert. pharm. 1916,
v. 28, part 1, p. 25-26, from J. suisse pharm. Nov. 4, 1915; see also
J. Chem. soc. 1916, v. 110, part 2, p. 654-655; Anal. chim, Analyt.
1916, v. 21, p. 208-209.
97
Rowe: The albumin and globulin content of human blood serum
1 health, syphilis, pneumonia, and similar infections —Arch, Int.
Med. 1916, v. 18, p. 455473.
Bloor, W. R.: A description of a quantitative colorimetric pro-
edure for the determination of cholesterol in the blood. The
method is based on the Liebermann-Burchard color reaction.—J.
Biol, Chem. 1916, v. 24, p. 227-231.
~Csonka, Frank A.: A critique of certain data on the content of
‘cholesterol and fatty substances in the blood, together with a modi-
fication of the colorimetric method for estimating cholesterol.—
J. Biol. Chem. 1916, y. 24, p. 431-438.
Reyveillet: A modified Grimbert method for the detection of
biliary pigments and urobiline in the blood serum.—Répert. pharm.
11916, v. 28, part 1, p. 352-353 from Union Pharm. June 15, 1916.
STAINS.
| Beninas, T. H. C.: Descriptions of methods for relief staining of
bacteria gna spirochetes.—Brit. M. J. 1916, v. 2, p. 722.
_ Anon.: The nickel-plated metal case in aphich stick shaving soap
is usually packed is stated to be a suitable and inexpensive container
tor use in staining acid-fa: M. Assoc. 1916, v. 66,
Pp. 1923.
Stovall, W. D., and Nichols, M. G.: Directions for the prépara-
tion of a Pebilized gentian- violet differential stain. It is claimed
that the stain prepared according to the directions will keep for three
‘months under ordinary laboratory conditions——J, Am. M. Assoc.
mavl6, v. 66, p. 1620.
_ Miller, A. H.: An explanation of the biochemistry of the loss of
“power of the tubercle bacillus to staining with carbol-fuchsin.—
J. Path. & Bact. 1916, v. 21, p. 41-46.
Keilty, R. A.: A note on the use of 30 per cent HCl! for decoloriz-
ing substances which interfere with the differentiation of tubercle
Ybacilli—J. Am. M. Assoc. 1916, v. 66, p. 1619.
Klein, E.: A description of a new Acacia for the staining of
tubercle bacilli—New York M. J. 1916, v. 103, p, 217.
<: Cerquera, D.: A description of an iniproved method for staining
“tubercle bacilli—J. Am. M. Assoc. 1916, v. 66, p. 231 from Brazil
“Medico, 2915, -v. 29, p. 321,
¢ Tribondeau, L., Fichet, M., and Dubreuil, J.: A method for stain-
ing the hairs of bacteria—Compt. rend. soc. biol. 1916, v. 79, p.
T10-716,
_ Botez, A.: Some new facts relative to the employme nt of methyl]
_ violet as a means for differentiating the organisms in the series
_typhi- coli.—Compt. rend. soc. biol. 1916, v. 79, p. 888-890.
-
110095°—19——-7
Leitch, Archibald: On the use of brilliant-green and telluric ac id
in the isolation of ty phoid-paratyphoid bacillii—Brit. M. J. 1916,
v. 2, p. 317-318.
Lipp, Hans: A description of the methods employed for stainin
gonococci.—Sudd. Apoth.-Ztg. 1916, v. 56, p. 30-81.
Dupray, Martin: A stain, pansisting “e thionin 0.5 gm., phenol
(crystals) 2 gm., distilled water 100 mils, is offered by the autho
for use in the detection of the endameeba in pyrrohea alveolaris.—
J. Am. M. Assoc. 1916, v. 66, p. 507-508. ;
CULTURE MEDIA,
Schneider, Albert: The addition to the U. S. P. of the chapter on
culture media is timely and desirable. The directions for making
these media are, however, inadequate, and do not conform to the
routine and official methods now in use in bacteriological laboratories. —
A far’more satisfactory plan would have been to simply name the
culture media, giving the ingredients, perhaps, and directing that
they be prepar ve in accordance with the latest approved and adopted —
recommendations of the committee on methods of the American —
Public Health Association—Drug. Cire. 1916, v. 60, p. 694.
Hurwitz, 8. H., et al.: A description of a colorimetric method for
the determination of the hydrogen ion concentration of biological —
ean with special reference to the adjustment of bacteriological cul- —
, Vv. 27, p. 16-24. 3
C oe Wm. 1 moh Tate Tethers A.: A list of indicators for use —
in the colorimetric determination of the hydrogen-ion concentration ~
Acad. Se. 1916, —
y. 6, p. 483-489.
Smith, A. R.: Notes on bacteriological technique, with special ref- —
erence to the preparation of culture media.—Pharm. J. 1916, v. 96,
p. 189-190, 421-422, 639-641; v. 97, p. 294-295.
Gaehtgens, W.: A report of experiments with the use of potato —
infusion for making solid culture media—Chem. Zentralbl. 1916,
2. p. 191.
Bourdet, L.: A report of experiments showing the development of —
acidity in culture media due to the action of the alkaline salts of these
media during sterilization in the autoclave-—Compt. rend. soe. biol.
1916, v. 79, p. 665-668.
Homer, Annie: A suggestion as to the cause of lessened production
of indol in media containing glucose.—J. Hyg. 1916, v. 15, p. 401-404.
sierry, H.: Notes on the preparation and sterilization of certain
albuminous culture media.—Compt. rend. soc. biol. 1916, v. 79, p.
270-272.
99
‘Distaso, A.: A note on digested and diluted serum as a substitute
or broth for bacteriological purposes.—Brit. M. J. 1916, v. 2, p.
555-556; see also Compt. rend soc. biol. 1916, v. 79, p. 599-601.
- Loffi, K.: A discussion concerning modified culture media and the
use of Siegfried’s proteose in place of meat extract—Sudd. Apoth.-
Zig. 1916, v. 56, p. 54.
- Guggenheimer, Rudolf: On yeast extract peptone agar as a sub-
stitute for meat extract peptone agar.—Centralbl. f. Bakteriol. 1916,
v. 77, p. 363.
_ Renlinger, P.: A discussion of the suitability of snail boullion as a
nutrient medium suited to the exigencies of the field work with
troops.—Compt. rend. soc. biol. 1916, v. 79, p. 1109-1110.
_ Cole, S. W., and Onslow, H.: A detailed description of a pan-
creatic digest z casein useful as a ee for peptone in the prepa-
Beton of culture media.—Lancet, 1916, v. 2, p. 9-11.
— Dujarric, R., and La Riviére: A pyle of a method for pre-
paring an orange gelose culture medium. An abstract-——Compt.
rend. soc. biol. 1916, v. 79, p. 843.
Jouan, C.: A method for the preparation of a litmus whey culture
medium is described.—Compt. rend. soc. biol. 1916, v. 79, p. 520-522.
Douglas, S. R., and Colebrook, L.: Experimental data showing the
advantage of using a broth containing trypsin in making blood cul-
tures.—Lancet, 1916, v. 191, p. 180-183.
Indgeon, Leonard S., et al.: Observations on the effect of the addi-
tion of fresh human blood serum to artificial media.—Lancet, 1916,
y. 191, p. 314-319 |
Lewis, M. L.: The advantages possessed by sea water as a culture
medium are described.—Physiol. Abstr. 1916, v. 1, p. 72.
Watabaski, Tomomitsu: From experiments, it is concluded that
blood agar and blood broth are still the most suitable culture media
is. 1916, v. 19, p. 733-735,
Hall, I. C.: A description of a sterilizable culture medium for
gonococcus in which a testicular infusion of agar is employed.—
Yearbook of Pharmacy, 1917, p. 35 from J. Bacteriol. 1916, v. 1,
p. 343.
Watabiki, Tomomitsu: A description of a culture medium for
gonoc ey Infec. Dis. 1916, v. 19, p. 733-735.
Holt-Harris, J. E., and riieh aus! Oscar: A description of a new
culture medium for the isolation of Bacillus typhosus from stools.—
J. Infec. Dis. 1916, v. 18, p. 596-600.
Teague, O., and Clurman, A. W.: A method for the preparation
of an improved brilliant-green culture medium for the isolation of
typhoid bacilli from stools.—J. Infec. Dis. 1916, v. 18, p. 647-652.
100
Krumwiede, Charles, jr., et al.: Experiments with the use of bri
liant-green for the isolation of typhoid and paratyphoid bacilli fro
feces.—J. Infec. Dis. 1916, v. 18, p. 1-13.
Robinson, Harold C., and Rettger, Leo F.: Studies on the use o
brilliant-green and a modified Endo’s medium in the isolation of
Bacillus typhosus from feces.—J. Med. Research, 1916, v. 34, pv
363-376.
Gibson, H. G.: A new solid culture medium for the isolation of
cholera vibrio—Brit. M. J. 1916, v. 2, p. 454-455.
Lloyd, Dorothy J.: Gominewt. on the technical details in the
preparation of a transparent blood-agar for the cultivation of the-
meningicoccus.—Brit. M. J. 1916, v. 2, p. 148-144. ;
Gordon, M. H., et al.: An experimental study of the cultural re-
quirements of the meningococcus.—Brit. M. J. 1916, v. 2, p. 678-684. |
5. APPARATUS AND CONTAINERS.
Hamburger, H. J.: On the use of the centrifuge in the chemical
laboratory. —Chem. Weekblad, 1916, v. 13, p. 656-643.
Fouque, G.: An illustrated dpe aeer of a device for siblamane
and weighing small janantiies of iodine.—Bull. soc. chim. France,
1916, v. 19, p. 270-272; see also Analyst (The), 1916, v. "41, p. 322.
For eee John W.: An illustrated description of an app for
automatic percolation and drug extraction—J. Am. Pharm. Assoe.
1916, v. 5, p. 1258-1259.
Besson, A. A.: An illustrated description of a new form of ethor
extraction apparatus for use in food investigation—Pharm. Ztg.
1916, v. 61, p. 116.
Neidle, Marks: An illustrated description of a simple rapid dia-
lyzer.—J. Am. Chem. Soc. 1916, v. 38, p. 1270-1272.
The Earl of Berkeley: An illustrated description of a new form of
distilling flask—2J. Chem. Soc. Lond. 1916, v. 109, p. 520-523,
Pierce, C. E.: A description of a homemade water still, which
costs $2.50.—Drug. Cire. 1916, v. 60, p. 266.
Smith, O. C., and Morgan, D. G.: A simple mercury sealed ether
still. Illustrated—J. Ind. & Eng. Chem. 1916, v. 8, p. 1039.
Nunn, A. W.: An illustrated description of a hot-water funnel
made from the neck of a tin can and an ordinary tin pot. An ab-—
stract.—Drug. Cire. 1916, v. 60, p. 209.
Anon.: An illustrated description of a porcelain funnel for filter-
ing by suction which requires no rubber or cork stopper.—Chem.-Ztg.
1916, v. 40, p. 595.
Clapp, F. C.: An illustrated deseription of a nonspattering wash
bottle—J. Am. Chem. Soc. 1916, v. 38, p. 1502-1503.
101
Nunn, A. W.: An illustrated description of an apparatus for
washing bulky precipitates The apparatus is constructed from a
funnel, a clean flower pot, and a straining cloth. An abstract.—
Drug. Gin. 1916, v. 60, p. 209.
- Stratton, 8. W.: : Detailed descriptions of methods for the testing
_ of glass volumetric. apparatus.—Cire. Bur. Stand. 1916, No. 9, p.
1-82.
_ Tamback, R., and Zutavern, P.: A description of a new measuring
/ apparatus with a simultaneous inflow and outflow.—Ztschr. agnew.
Chem. 1916, v. 29, p. 268.
Rowe, Albert Ti.: An illustrated description of an automatic
pipette for the repeated measurements of small quantities of fluids —
J. Lab. & Clin. Med. 1916, v. 1, p. 439-441.
Lowry, Alexander: eo illustrated description of an automatic
pipette —J. Ind. & Eng. Chem. 1916, v. 8, p. 734-735.
- Bailey, H. S.: An illustrated description of a convenient form of
| weighing burette—Chem. Abstr. 1916, v. 10, p. 3003.
— Johnstone, J. O.: An illustrated description of a burette-filling
device-—Chem Abstr. 1916, v. 10, p. 1611.
| Cayaux, H. B.: A description of a method for preparing molds
_ of plaster of Paris for making vaginal suppositories.—Apoth.-Ztg.
1916,-v. 31, p. 34.
ee itis: A description of a method for making a simple form of
| pull counter. An abstract——Pharm. Era, 1916, v. 49, p. 24.
_ Nagai, N.: An illustrated description of an apparatus for the
manufacture of alkyl iodides. An abstract—J. pharm. et chim.
i916, v. 14, p. 213.
' Collings, C. H.: A description of a simple apparatus for the re-
‘covery of bromine from used hypobromite solutions—Chem. News,
1916, v. 14, p. 259.
Wieisa®, Harry B.: A description of a modified Victor Meyer ap-
- paratus for the determination of vapor densities.—J. Phys. Chem.
a 1916, v. 20, p. 532-538.
_ van Kregten, J. R. N.: A description of a simple colorimeter for
~ determining the purity of oils—Chem. Weckblad, 1916, v. 13, p.
_ 1157-1159.
Weisz, R.: Llustrated descriptions of apparatus for the deter-
p. 33-36.
F Pittenger, P. S.: An illustrated description of a multiple operat-
Bing table for use in blood pressure experiments.—J. Am. Pharm.
_ Assoc. 1916; v. 5, p. 1178.
Pittalibrer, P. S.: An illustrated description of a water bath that
_ will maintain a constant temperature either above or below that of
_ the room—J. Am. Pharm. Assoc. 1916, v. 5, p. 1260.
102
Nicolardot, Paul: A report of investigations to determine the
resistance of French, Bohemian, and German glass to chemi
reagents.—Compt. rend. acad. se. 1916, v. 163, p. 355-357.
Javillier: A study of the effect of the zine content of glass on t
development of Aspergillus niger —C. U. C. P. Alumni J. 1916, v.
23, p. 34.
Bordier, H.: A study of glass bottles for the purpose of deter-
mining the colors which are best suited for protection of the contents
against the actinic rays of light.—Compt. rend. acad. se. 1916, v. 163,
p. 105.
Krébere: A study of the effect of alkalinity of glass on the con-
tents of ampoules. An abstract.—Drug. Circ. 1916, v. 60, p. T47.
Paul, T.: A discussion of the changes occurring in liquids in glass
ampoules, together with the causes and phenomena productive
thereof and incidental thereto.—Sudd. Apoth.-Ztg. 1916, v. 56, p. 459.
Dané, A.: An illustrated description of a jet and dropping bottle
for hospital use-— Yearbook of Pharmacy, 1916, p. 347, from L’Union
pharm. 1916, v. 57, p. 7.
Anon.: An illustrated description of a glass tube now being used
in Germany to replace the collapsible tin tube as a container for oint-
ments and pastes.—Chem. & Drug. 1916, v. 88, p. 964.
Weston, Paul G.: An illustrated description of a simple container
for blood cultures—J. Am. M. Assoc. 1916, v. 66, p. 507.
Anon.: An illustrated description of a new glass stopper for re-
agent bottles.—Chem.-Ztg. 1916, v. 40, p. 399.
6. FILTERS.
Scoville, Wilbur L.: A report of results obtained in experiments
cn filtration, the object of which was to determine the most satis-
factory medium for use in pharmacy.—J. Am. Pharm. Assoc. 1916,
v. 5, p. 906—509.
Jadidi, S. L.: A note on the applicability of the paper pulp filter
to the separation of solids from liquids.—J. Franklin Institute, 1916,
v. 182, p. 61-67.
Shuey, Ralph C.: An illustrated description of a rapid filter for
turbid liquids.—J. Ind. & Eng. Chem. 1916, v. 8, p. 523.
Firth, M.: An illustrated description of a simple pressure filter
suitable for thick liquids. An abstract—Drug. Cire. 1916, v. 60,
p. 418.
7. VEGETABLE DRUGS.
Gathercoal, E. N.: A list of the various botanical drugs recognized
in 19 different pharmacopceias.—J. Am. Pharm. Assoc. 1916, vy. 5,
p- 286-293, 416-421, and 520-528,
Editorial: The monographs on vegetable drugs in the U. 8. P. IX
are exceptionally complete. Few facts appear to have been omitted
105
which would prove of value in determining the identity in quality
of these products. These monographs are a great credit to the
chairman of the committee on botany and pharmacognosy and place
the subject of pharmacognosy as one of the important divisions of
- pharmacy.—Northwestern Druggist (The), 1916, v. 17, No. 8, p. 24.
Kraemer, Henry: The conservation and preservation of crude and
powdered drugs have, for the first time, received the attention that
the subject warrants. This has not been by any means exhaustively
treated. But the precautions given will be found very practical
and will undoubtedly prove of great value to the retail pharmacist
‘in preventing the deterioration of his stock as well as monotary
~ loss.—Pharm. Era, 1916, v. 49, p. 387.
Parry, Ernest J.: In the statement in connection with the preser-
~yation of vegetable or animal substances that portion which reads
“Tt is not intended that this precaution should be used for drugs
imported in bales or large original containers ” is characterized as
silly —Chem. & Drug. 1916, v. 88, No. 1913, p. 40.
Schneider, Albert: A most notable omission in the U. 8. P. de-
scriptions of vegetable drugs is the failure to mention the behavior
of starch granules under polarized light. On the other hand, fre-
quent reference is made to the polarizing manifestations of such
diagnostically unimportant substances as inulin, micro-crystallin,
calcium oxalate, and resin particles, without, however, specifying
_ what use or value, if any, these phenomena might have.—Drug. Cire,
1916, v. 60, p. 693.
_ Editorial: The new definitions and extended requirements of the
~Pharmacopeeia will tend to increase the pharmacist’s study of the
collecting, packing, and storing of drugs in order that he may know
the conditions they have passed through to reach him and in order
that he may be able to value them accurately when they reach his
store—Pharm. Era, 1916, v. 49, p. 380.
Scoville, Wilbur L.: The descriptions of vegetable drugs in the
U. S. P. TX are very full and verbose. Some of the sentences are
not very illuminating except to an analytical botanist. Fortunately
the retail druggist uses but very few vegetable drugs, and the botani-
eal descriptions will trouble him but little—Bull. Pharm. 1916, v.
30, p. 280.
Rusby, H. H.: The extensive descriptions which appear under
‘yegetable drugs can not serve any practical purpose at the present
time except in a few cases, but they may become important at any
time in the future due to the fact that new adulterants and impuri-
ties are continually making their appearance.—Drug. Cire. 1916, y.
60, p. 539.
Scoville, Wilbur L.: A “purity rubric” adopted for most of
the vegetable drugs in fhe Pharmacopeia is a statement which limits
164
the amount of stems and “other foreign matter” which can b
allowed, and also places a limit on the yield of ash—Bull. Pharm.
1916, v. 30, p. 362-363. _-
Rasby, H. H.: An unfortunate formula that appears in the speci-
fications for the purity of a number of vegetable drugs is that o
“or other foreign matter,” instead of “and other foreign matter.”—
Drug. Cire. 1916, v. 60, p. 536. %
Swildens, Johs. Jelgerhuis: Samples of the pharmacognostical
descriptions intended for the Ph. Ndl—Pharm. Weekblad, 1916, vy.
43, p. 1565-1571. 4
Alsberg, C. L.: Tentative standards laid down by the Bureau of
Chemistry are given for sabadilla seed, savory leaves, fenugree
seed, celery seed, and manna.—S. R. A.-Chem. 1916, No. 16, p. 30.
Jones, H. W.: A plea for further study of the chemistry and
therapeutic activity of green plant drugs.—J. Am. Pharm. Assoe. |
1916, v. 5, p. 1340-1343. |
Menzel, Max: The buying of drugs, chemicals, and pharmaceutical
preparations. A practical discussion—Proc. Minnesota Pharm,
Assoc. 1916, p. 100-102.
Johnson, William N.: An enumeration, with descriptions, of some
of the drugs used by pioneers.—Spatula (The), 1916, v. 22, p.
295-296.
Piorkowski: A discussion of the use of algz and lichens as auxil-
iary and substitute materials for pharmaceutical purposes. Atten-
tion is directed to the possibility of substituting the mucilaginous
extract of Irish moss for ointment bases, cold creams, glycerin, soap,
etc.—Chem. Zentralbl. 1916, v. 2, p. 158.
Youngken, H. W.: A discussion of the economic importance of
some members of the bayberry family. Information is given regard-
ing their occurrence, constituents, and the technical uses to which the
latter may be apphed.—Drug. Cire. 1916, v. 60, p. 5-6.
van de Wielen, P.: A discussion of methods for the curing of
vegetable drugs so that they may be preserved without change. An
abstract—Chem. & Drng. 1916, v. 88, p. 774-775.
Wodehouse, R. P.: A description of a simple method for obtain-
ing ragweed pollen in Jarge quantities—Boston M. & S. J. 1916, v.—
174, p. 430.
Anon.: Random notes on the flora of the dunes in northern
i-rance.—Pharm. J. 1916, v. 97, p. 274.
Mouschinski: An enumeration, with descriptions, of some of the
follk remedies used in the Caucasus.—J. pharm. et chim. 1916, v. 13,
p. 162-165 from Pharmazevtizeski J. 1915, p. 487.
van Berk, L. H.: Notes on the indigenous medicinal plants of Hol-
jland.—Pharm. Weekblad, 1916, v. 53, p. 862-865,
105
Anon.: A list of Italian medicinal plants compiled by Prof. Cor-
_tese.—Chem. & Drug. 1916, v. 88, No. 1879, p. 175.
- Rosendahl, H. V., and Séderberg, I.: A contribution relative to the
pteridophyte flora of Gothland.—Svensk farm. Tidskr, 1916, v. 20,
pp. 509-515, 529-534.
_ Anon.: A report on the constituents and physiologic action of some
4, p. 27-87; see also Chem. Abstr. 1916, v. 10, p. 2386.
- Plowmar, Sydney: Brief notes on some of the medicinal plants of
| Australia—Pharm. J. 1916, v. 97, p. 823; see also Chem. & Drug.
1916, v. 88, No. 1903, p. 49.
Rodway, James: An enumeration and description of some of the
‘bush medicines ” used by the natives of British Guiana.—Chem, &
MDrug. 1916, v. 88, No. 1875, p. 54.
- Kokantur, V. R.: An enumeration of some of the drugs used in
pharmaceutical practice in India.—Proc. Minnesota Pharm. Assoc.
| 1916, p. 195-199.
% Anon.: A survey of the drug resources of India and the other
_ British colonies.—Pharm. J. 1916, v. 97, p. 49-82.
Linton, Arthur W.: An historical account of East Indian voyages
of the sixteenth and seventeenth century in their relation to drugs,
| spices, and dyestuffs—J. Am. Pharm. Assoc. 1916, v. 5, p. 250-255,
366-380, 471-481, 574-589. -
Hansen, Carl C.: A report on the production of crude drugs and
| spices in Siam for the year 1915.—Com. Rep. 1916, No. 55, p. 916.
_ Bell, C. C.: In connection with the tercentenary celebration of
' Shakespeare’s birth, the author has published a review of the medical
references in Shakespeare’s works. References to drugs and remedies
are given—Chem. & Drug. 1916, v. 88, p. 765.
Small, James: A discussion of the economy noticeable in the de-
_ velopment of the plants of the Composite family.—Pharm. J. 1916,
vy. 97, p. 865-366.
- Hanausek, T. F.: A review of the work by A. Tschirch entitled
_ Handbuch der Pharmakognosie—Pharm. Pest, 1916, v. 49, p.
~ 119-120.
Anon.: A review of the second edition of Potter’s Cyclopadia of
>.
3 Botanical Drugs and Preparations states that the volume is a handy
:
4
_ yeference work on botanic drugs. giving an alphabetical list of the
~ botanical names, common names and synonyms of a large number
of official and unofficial drugs of commercial value—Drug. Cire.
1916, v. 60, p. 33.
2 Anon.: A review of Southall’s Organie Materia Medica, revised
: and enlarged by Ernest W. Mann, states that the volume is a hand-
; bock treating of the more important of the animal and vegetable
106
drugs made use of in medicine, including the whole of those con-
tained in the Ph. Brit., and is designed for the use of teachers, phar.
maceutical and medical students, chemists, druggists, and others.
Pharm, J. 1916, v. 96, p. 112.
Anon.: A book review of Scientific and Applied Pharmacognosy,
by Henry Kraemer, states that the work will surely prove indis-
pensable to pharmacists, and should be of much service to botanists
in other fields —Am. J. Se. 1916, v. 41, p. 380.
W. C. De G.: A book review of a small volume by D. H. Webster
on pharmacognosy for apprentices in pharmacy. The book is en-
titled Pharmacognosie in tabellen-vorm, ten gebruike bij de opleid-
ing voor apothekers-adsistent—Chem. Weekblad, 1916, v. 13, p. 1192.
Anon.: A book review calls attention to a small pamphlet by G.
Arends on the household use of medicinal plants indigenous to Ger-
many.—Pharm. Weekblad, 1916, v. 53, 1387.
Anon.: A book review calls attention to the fifth edition of the
botanical part of a work by E. Gilg entitled Schule der Pharmazie.—
Schweiz. Apoth.-Ztg. 1916, v. 54, p. 34.
Anon.: A book review calls attention to a volume by G. Stuart
Gager entitled Fundamentals of Botany.—Pharm. Era, 1916, v. 49,
0. 452.
: 1. CULTIVATION OF MEDICINAL PLANTS.
Anon.: A compilation of references to articles on the cultivation
of medicinal plants which have appeared in the Druggists’ Cireular
from time to time.—Drug. Cire. 1916, v. 60, p. 603.
Youngken, H. W.: A paper discussing phases of drug plant culti-
vation that must be solved before the undertaking will be a commer-
cial success — Am. J. Pharm. 1916, v. 88, p. 171.
Stockberger, W. W.: A discussion of how to cultivate medicinal —
plants, based on experimental work conducted at the Bureau of Plant |
Industry.—Pharm. Era, 1916, v. 49, p. 179.
Ballard, C. W.: A discussion of our unpreparedness for carrying
on the cultivation of medicinal plants at the present time.—Am.
Druggist, 1916, v. 64, p. 260.
Stockberger, W. W.: An illustrated review of the available in-
formation relating to medicinal plant gardens operated in connec-
tion with teaching institutions. Also a review of some of the recent
efforts to popularize the cultivation of drug plants—J. Am. Pharm.
Assoc. 1916, v. 5, p. 1068-1075.
Anon.: Short notes giving information and directions necessary
to the cultivation of a number of medicinal plants.—N,. A. R. D. J.
1916, y. 21, p. 702-704, 804-805, 916-917, 1056-1058, 1113-1114, 1274-
1275; v. 22, p. 215-217, 420-422, 572-574, 674-675, 1024-1025, 1172-
1174; y. 23, p. 283-234, 504-505,
107
Johnson, William N.: Some notes on the home cultivation of
medicinal plants—Spatula (The), 1916, v, 22, p. 465-467.
_ Schlichting, A. F.: Comments of a general nature on the grow-
“ing of medicinal plants.—Northwestern Druggist (The), 1916, v.
“1, No. 10, p. 42-43.
_ Holmes, E. M.: A discussion of the subject of the cultivation
of medicinal plants and the collection of herbs—Pharm. J. 1916,
-y. 96, p. 101-102, 161-162.
_ Arny, L. Wayne: A general discussion of the methods employed
it improving strains of medicinal plants under cultivation —Mul-
| ford’s Vet. Bull. 1916, v. 7, p. 100-103.
' Kilmer, Fred B.: A discussion of the commercial future of drug
qultivation in the United States—Proc. New Jersey Pharm. Assoc.
1916, p. 45-46.
_ Anon.: A short article pointing out the limitations of the market
to drug-plant growers. Mint, belladonna, digitalis, and lemon grass
“may be cultivated, but the country needs only a small supply.—
Am. Food J. 1916, v. 11, p. 504.
_ Kraemer, Henry: A short discussion outlining the progress made
in the cultivation of medicinal plants in the United States —J. Am.
Pharm. Assoc. 1916, v. 5, p. 271-272.
van Loren, H. A.: Notes on the cultivation of medicinal plants in
ornamental gardens.—Pharm. Weekblad, 1916, v. 53, p. 121-129,
146-154, 199-202, 296-298, 342-349, 515-520, 631-637, 849-860, 1108-
1116, 1262-1266, 1416-1423, 1690-1694.
_ Newcomb, E. L.: Notes.on medicinal plants grown in the medici-
nal plant garden of the College of Pharmacy of the University of
-Minnesota.—Proc. Minnesota Pharm. Assoc. 1916, p. 175-180.
Day, Elsie: A short article discussing the cultivation of medicinal
plants at the University of Nebraska.——Proc. Nebraska Pharm.
Assoc. 1916, p. 73-77.
Jones, D. F.: A list of the medicinal plants growing in South
Dakota is presented.—Northwestern Druggist (The), 1917, v. 18,
No. 9, p. 54-56.
Sayre, L. E.: A description of a garden at Douglas, Mich., which
yields over 500 pounds of hydrastis annually.—Drug. Cire. 1916, y.
60, p. 601.
Linton, Arthur W.: A discussion of the present status of medici-
nal plant cultivation in the Northwest.—Proc. Washington Pharm.
assoc. 1916, v. 61-67.
Maxwell, A. F.: A short report on the cultivation of drug plants
in eastern Washington—Proc. Washington Pharm. Assoc. 1916,
p. 59-61,
108
London letter: A review of a lecture by E. N. Holmes on cultiva-
tion of medicinal herbs in England.—J. Am. M. Assoc. 1916, v. 66
p. 1568.
Anon.: It is stated that a medicinal plant nursery has been
started at Chalfont St. Peter, Buckinghamshire, England, where
students are given instruction in the cultivation and harvesting of
mecicinal plants—Chem. & Drug. 1916, v. 88, p. 893. q
Hale, Franklin D.: A note calls attention to the formation of the
Women’s Herb Growing Association in England, which has for
its object the interesting of women in the cultivation of medicinal
herbs wherever possible-—Com. Rep. 1916, No. 49, p. 820.
Guerman, P.: Notes on the cultivation and collection of medici-—
nal plants in France.— Yearbook of Pharmacy, 1916, p. 264-265 from
L’Union Pharm. 1916, v. 57, p. 121.
Zornig, Johann: A review of past results and future josie
relative to the economic and commercial aspects of drug cultivation
in Germany.—Pharm. Zentralh. 1916, v. 57, p. 244.
Anon.: Notes on the cultivation of chicory seed in Germany.—
Oil, Paint & Drug Rep. 1916, v. 90, No. 14, p. 81.
Frost, Wesley: A note states that the Society of United Irish”
Women has taken up the subject of the culture of herbs in order
to supply the demand for those drugs which are urgently needed.—
Com. Rep. 1916, No. 49, p. 825.
Maiden, J. H.: A paper dealing with the cultivation of medicinal
plants in New South Wales as affected by climatic and soil condi-
tions.—Australas. J. Pharm. 1916, v. 31, p. 251.
Anon.: The President of Uruguay has directed the National In-
spection Bureau of Live Stock in Agriculture to prepare a program —
of study and experiments on the cultivation and acclimatization of
foreign medicinal plants, and also on the medicinal properties of ©
native plants.—Com. Rep. 1916, No. 211, p. 925
Hfooper, David: An article on the important drugs indigenous to,
or cultivated in, India.—Chem. & Drug. 1916, v. 88, p. 786.
2. POWDERED DRUGS.
Schneider, Albert: The introduction into the U. S. P. IX of de-
scriptions of the microscopical characteristics of vegetable drugs
and the powders made therefrom is by far the most important
change in the entire work of revision. This one change alone places ©
the U. S. P. in the front rank of the world’s pharmacopeias.—
Drug. Cire. 1916, v. 60, p. 692. .
Schneider, Albert: Keys to the study and identification of simple
powdered vegetable drugs.—Pacifie Pharm. 1916, v. 10, p. 152-158.
109
Wallis, T. E.: A description of a method for the quantitative
eroscopic examination of powder mixtures. The method consists
f mixing the powder with a definite amount of lycopodium, suspend-
ing in a liquid, and examining under the microscope.—Analyst (The),
ondon, 1916, v. 41, p. 357-375.
Ballard, C. W.: Descriptions of the appearance of a number of
lifferent plant tissues when viewed under polarized light—J. Am.
harm. Assoc. 1916, v. 5, p. 1823-1326.
‘Tschirch, A.: A comparative anatomy outline for solving ques-
ons in applied pharmacognosy.—Schweiz, Apoth.-Ztg. 1916, v.
t, p. 445-449.
Wall, Otto A.: A short historical account of the early develop-
ent of vegetable taxonomy.—J. Am. Pharm. Assoc. 1916, v. 5, p.
4-963.
Greenish, Henry G.: Descriptions of microscopical methods, with
special reference to the examination of drugs.—Analyst (The), 1916,
y. 41, p. 195-202.
~ Dezani, S.: A comprehensive review of recent literature bearing
-on microsublimation and its application to the chemical investiga-
tion of drugs—Chem. Zentralbl. 1916, v. 1, p. 1034.
_ Anon.: A review: of a volume by William Mansfield entitled
| Histology of Medicinal Plants—Bull. Pharm. 1916, v. 30, p. 519.
3. MOISTURE DETERMINATIONS.
_Folpmers, T.: A description of a direct method for the determina-
tion of the moisture content of spices. The article includes data ob-
tained by employing various different methods.—Chem. Weekblad.
1916, v. 18, p. 14-16.
_ Azzarello, E.: A description of a method for the determination
of moisture in resinous woods. Illustrated—Ann. chim. applicata.
61916, v. 6, p. 154-157.
_ Willing, P. A.: A description of an automatic apparatus for the
“determination of moisture—Chem. Zentralb]. 1916, v. 1, p. 1213-
1214.
_ Mallinckrodt, Edward: A review of methods for the determination
-of small amounts of aleohol and water in ether, with an outline of
a modified specific gravity method as described by Reginault and
drian.—J. Ind. & Eng. Chem. 1916, v. 8, p. 807-812.
- Roark, R. C.: A report on the analysis of insecticides includes the
‘results of a study of the determination of moisture in these ma-
terials—J. Assoc. Off. Agric. Chem. 1915, v. 1, p. 485-457.
_ Anon.: A discussion of the occurrence and determination of water
in creosote—Chem. Abstr. 1916, v. 10, p. 107 from Proc. Am. Roy.
“Eng. Assoc. 1915, v. 16, p. 827-832.
110 —
West, R. M.: A report on the use of the calcium carbide me
for the determination of moisture in syrups.—J. Ind. & Eng. Chem.
1916, v. 8, p. 31-35.
McGee, W. J.: A report of investigations dealing with the de-
termination of moisture in various foods by means of dehydrating
agents, such as H,SO,, CaC., Na, CaCl,, P,O;, and BaO,.—J. Assoe.
Off. Agric. Chem. 1915, v. 1, p. 218-221.
Ronnet, L.: Notes on the determination of water in confechoa
jellies, and marmalades.—Ann. Falsif. 1916, v. 9, p. 145-146. ;
Winge, O.: A reply to a criticism of tic author’s work on the
determination of moisture in hops.—Chem. Abstr. 1916, vy. 10, p. 798.
4. ASH DETERMINATION.
Schneider, Albert: The ash percentages given in the U. S. P. are
in some instances high, in fact, so high as to serve as an encourage-
ment to the sophisticators. In the case of asafetida, it would be
impossible to obtain the pharmacopeeial ash standard (80 per cent)
without adulterating the drug heavily with sand, clay, diatomaceous
earth, dirt, or perhaps a very high percentage of vegetable matter
rich in silica, as gramineous chaff.—Drug. Cire. 1916, v. 60; p. 693.
Tschirch, A.: A discussion of the causes for the wide variation in
the ash content of digitalis, hyoscvamus, sage, kamaia, anise, saffron,
valerian, and sarsaparilla.—Schweiz. Apoth.-Ztg. 1916, v. 54, p. 461-
465.
Boltz, G. E.: A description of a modified method for the deter-
mination of carbon-free ash in plant substances.—J. Ind. & Eng.
Chem. 1915, v. 7, p. 859-860. )
Jerry, R. A.: A table showing the potash and phosphoric acid
content of various wood ashes.—J. Soc. Chem. Ind. 1916, v. 34,
p. 1263.
Bryant, A. P.: A note concerning the determination of the alka-
linity of ash obtained in the analyses of organic materials.—J. Ind.
& Eng. Chem. 1916, v. 8, p. 757.
5. GLUCOSIDES.
Vintilesco, J.: Observations on the réle of glucosides in plants.—
Chem. Zentralbl. 1916, v. 19, p. 851.
Kobert, R.: Notes on the classification and significance of the
saponins.—Chem. Zentralbl. 1916, v. 2, p. 275.
Bourquelot, Aubry, Ciamician, and others: Experimental observa- —
tions on the isolation, synthesis, tev constitution of glucosides.—
J. pharm. et chim. 1916, v. 14, p. 225, 289, and 359; see also Compt.
rend. acad. se, 1916, v. 163, p. 60. and 312; Ann. chim. 1916, v, 6,
p. 5; J. Chem. Soc. Lond. 1916, v. 112, p. 41.
111
Tunmann, O.: A continuation of a report on researches concern-
‘ing the microchemistry of wsculin and its detection in Asculus hip-
| pocastanum Li.—Schweiz. Apoth.-Ztg. 1916, v. 54, p. 67-70.
Asahina, Yasuhiko, and Shimidzu, Toraji: An account of re-
searches on the saponin isolated from the epicarp of Sapindus muhu-
‘Tosi Gert.—J. pharm. et chim. 1916, v. 14, p. 188-190 from Yakuga-
‘kuzasshi anne, 1916, No. 410.
~ Bourquelot, Em., and Aubry, A.: An account of the biochemical!
synthesis of a galactoside of saligenin, the @-salicylgalactoside.—J.
pharm. et chim. 1916, v. 13, p. 273-279.
_ Kohn-Abrest, E.: In an account of the toxicological analysis of
water, the detection of glucosides is discussed.—Ann. Falsif. 1915,
y. 8, p. 207-211. ;
~ Cuoghi-Constantini, Luisa: Notes on the microchemical location
of the alkaloids and glucosides in some of the Ranwneulacee—Chem.
“Abstr. 1916, Vv. 10, p. 1661.
Straub, Walther: A discussion of the relationship between the
chemical constitution and pharmacological action of the substance
of the digitalis group.—J. Chem. Sec. Lond. 1916, v. 110, p. 618
from Biochem. Ztchr. 1916, v. 75, p. 132-144.
. Kiliani, H.: Descriptions of the glucosides of digitalis seeds and
‘some of their cleavage products.—J. Chem. Soc. Lond. 1916, v. 110,
p. 493-494 from Ber. deutsch. chem. Gesellsch. 1916, v. 49, p. 701-721.
Kraft, F.: U.S. Patent No. 1,180,657. A process for the extrac-
tion and purification of a glucoside from digitalis leaves.—Chem.
“Abstr. 1916, vy. 10, p. 1693. -
_ Pearce, R. G.: A report of the results obtained in experimental
‘researches to determine the effect of phloridzin on the digestive secre-
tions. An abstract.—J. Am. M. Assoc. 1916, v. 66, p. 1819.
6. ALKALOIDS.
- Lyons, A. B.: A general review of the changes in the alkaloidal
‘standards appearing in the new edition of the U.S. P., with a table
showing the relation of the old to the new standards.—J. Am. Pharm.
Assoc. 1916, v. 5, p. 1118-1120.
_ Slack, H. F.: Notes on the methods of isolation and the properties
of the alkaloids official in the Ph. Brit., 1914.—Pharm. J. 1916, v. 96,
Zp. 71--74.
~ von Weisse, G., and Lévy, Meyer: A report of experimental work
on the determination of the dissociation constants of some alka-
oids.—J. chim. phys. 1916, v. 14, p. 261-284.
Cohn, George: A discussion of advances in the improving of
natural alkaloids by changing accompanying alkaloids of no value
into useful medicinal compounds, the elimination of unpleasant or
harmful side actions without influencing the principal effect of the
1¥2
cinal compounds.—Pharm. Zentralh. 1916, v. 57, p. 299-303, 342-346,
875-381, 411-413, 431-436, 462-466, 510-514, 546-550, 577-580,
604-610.
Dott, D. B.: A short article dealing with the production of allka-
loids in Great Britain as affected by the war.—J. Soc. Chem. Ind.
1916, v. 35, p. 788-789.
Peset, Juan, and Buendia, Rogelio: A new reagent for producing
color reactions with alkaloids and similar compounds consists of a
mixture of sulphuric and titanic acids. The reactions of a number of
allxaloids are described.—Anales soc. espanola fis. quim. 1916, v. 14,
p. 257-263; see also Farm. Espan. 1916, v. 48, p. 503-505, SS i
Répert. ee 1916, v.28, part 1, p26. ;
Denigés, G.: A description of a general reaction for alkaloids —
possessing phenolic properties, such as morphine and its derivatives,
cupreine, adrenaline, etc. The reagent employed is a solution of
titanium oxide in concentrated sulphuric acid.—Bull. Soc. chim.
France, 1916, v. 19 and 20, p. 308-311; see also Ann. chim. analyt.
1916, v. 21, p. 213-916.
Filippi, Eduardo: A report of researches dealing with the chem-
ical and physiological identification of two or more alkaloids when ~
dissolved in the same solvent.—Arch. farmacol. sper. 1916, v. 22,
p- 120-130; see also Ann. Falsif. 1916, v. 9, p. 320. .
Hagmier, E. W.: A description of a method for the recovery of ©
cinchonine frem solutions in which it has been used to remove traces
of tungsten—Chem. Abstr. 1916, v. 10, p. 565.
Holste, Arnold: A report of researches to determine the pharma-
cological action of an alkaloidal base obtained from the peony.—
Chem. Zentralbl. 1916, v. 1, p. 1154. .
Neilsen, Carl: Descriptions of certain alkaloidal phosphotung-
states and of animal experiments conducted therewith.—Am. J. Clin.
Med. 1916, v. 23, p. 903-906. |
Hart, Merrill C.: A note on the berberine content of algerita root, —
Odostemon trifolatus (Moric.) Heller. The presence of hydrastine
could not be detected.—Am. J. Pharm. 1916, v. 88, p. 301-302.
7. MISCELLANEOUS PLANT CONSTITUENTS.
Schryver, Samuel B., and Haynes, Dorothy: Researches on the
preparation and properties of the pectic substances of plants——Bio- —
chem, J. 1916, v. 10, p. 539-547.
Rinkes, I. J., and van Hasselt, J. F. B.: Researches on the chem-
ical constitution of bixin, a constituent of annatto.—Chem. Week-
blad, Pie: v. 13, p. 436-442, 1224-1229; see also van Hasselt, p.
429-436.
113
al! Pie. ” J.: én the Mrapanition of the milky juice obtained from
Fabernemontana spherocarpa B\.—Chem. Weekblad, 1916, v. 13,
183-185.
Wells, H. Gideon, and Hendenburg, O. F.: Experimental data
howing the toxicity of carotin—J. Biol. Chem. 1916, v. 27, p. 213-
16.
Hart, Merrill C., and Heyl, Frederick W.: Analytical data con-
erning certain constituents of jambul.—J. Am. Chem. Soc. 1916,
98, p. 2805-2813,
‘Crawford, Albert C., and Watanabe. Walter K.: A note on the
ecurrence of p—hydroxyphenylethylamine in various mistletoes.—J.
Biol. Chem. 1916, v. 24, p. 169-172.
8. ASSAY PROCESSES.
Beringer, George M.: The changes in the assay processes of the
J. S. P. have introduced several new features, such as the use of
purified sawdust as a distributing medium, and the adoption of the
aliquot part method.—Am. Druggist, 1916, v. 64, No. 8, p. 24.
' Asher, Phillip: There is one feature regarding the assay methods
hat should be seriously considered by the revisers of the U. 8. P.,
d that is, to give a succinct explanation of the philosophies under-
ying these methods.—Southern Pharm. J. 1916, v. 9, p. 184.
_ Scoville, Wilbur I.: In an article entitled “ A plea for pharma-
seutical research,” the introduction into the U. S. P. of assays for -
gelsemium, lobelia, and veratrum is recommended.—Bull, Pharm,
1916, v. 30, p. 417.
_ Stout, Henry: Criticisms of the various volumetric assays of the
Wh. Brit—Pharm. J. 1916, v. 96, p. 190, 218-220, 245-246.
_ Beal, George D., and Brady, St. Elmo: A preliminary report on
the hydrochloride method for the determination of alkaloids.—J.
d. & Eng. Chem. 1916, v. 8, p. 48.
' Beal, George D., and Lewis, Harry F.: A general discussion of
experimental work with a variety of alkaloids. The authors con-
slude that the most practical method for the determination of alka-
loids involves the extraction of the latter from an aqueous solution by
means of an immiscible solvent, such as chloroform or ether and sub-
Sequent purification of the alkaloidal solution by similar methods.—
J. Am. Pharm. Assoc. 1916, v. 5, p. 812-8386.
110095 °—19-—_8
114
van Itallie: Comments on the Ph. Ndl. methods for determinir
the alkaloidal content of belladonna extract, pomegranate bark, an
quinine in various preparations.—Pharm. blades. 1916, v. 53, |
1661-1671. 4
Vanderkleed, C. E., and E’we, G. E.: A presentation of exper
mental data to show the necessity for treating alkaloidal residue
obtained by chloroform with ether before attempting to dry to con
stant weight. If this procedure is not followed, high results ai
obtained owing to the tenacity with which such residues retain chlor
form.—J. Am. Pharm. Assoc. 1916, v. 5, p. 713.
Dott: A note on the use of methyl orange as an indicator for
titration of alkaloids.—Pharm. J. 1916, v. 96, p. 368; see also Ann
Falsif. 1916, v. 9, p. 320.
Pereira, A. C.: A description of a method for the purification of
the chloroform and ether residues obtained in the forensic determina
tion of alkalotds—Chem.-Ztg. 1916, v. 40, p. 39.
Wilbert. M T.: Statistics relating to the assay methods and purity
requirements of the U. S. P. and N. F.—J. Am. Pharm. Assoc. 1916
v. 5, p. 1829-1331.
Carlinfanti, Carl, and Seelba, M.: A description of certain colori:
metric methods for the quantitative determination of the alkaloids
of nux vomica and opium.—Boll. chim.-farm. 1916, v. 55, p. 225-232
Anon.: Data showing the alkaloidal content of some solanaceous
drugs from South Africa.—Bull. Imp. Inst. 1916, v. 14, p. 21-27; see
also Chem. Abstr. 1916, v. 10, p. 2386.
Kissling, Richard: A diseussion of methods for the determinatior
of the nicotine content of tobaceo.—Chem.-Ztg. 1916, v. 40, p. 594-595,
Rasmussen, H. B.: A critical study of the Kissling, Bertrand and
Javillier, Keller, Toth, Chapm, Ulex, and Koenig methods for th
determination of nicotine in tobacco. Results obtained by the various
methods, including Rasmussen’s procedure as a standard (ef. C. A. 9,
3326), are reported and discussed in detail. Numerous references
to the literature are given.—Ztschr. anal. Chem. 1916, v. 55, p. $1-1333
see also Chem. Abstr. 1916, v. 10, p. 1575. ‘
“we, George E.: Presents the following comparison of assays of
crude drugs for the years 1909 to 1916, inclusive: :
Year. Total. | Above.| Below. abovall
Report of— |
PODGE Bean stew xe debater apelin & You pays nol Mem ode ee a 395 3 82 79.3
POD eA eee Toe Ei AA ee Ae es ee 340 291 | 49 } 85.
MOT oo 5 ma kiabint's sun kd caren ieee ae MEE cles Cone ee 263 224 | 39 85.1
1 by ee yo eR EAS ool KERERER HMMM RCI E Va 8 oe 298 35 | 63 78,
if yl Ree a Oe eel emer tee eee Ren ee 382 264 118 69.
WRI ln 3554. AEE Cs HOUOS AAO Le eee 286 221 65 77.
TOLD by ois wie ae alse eee 2 Uae wast py ctadibeels gees is een ea 133 98 35 73.6
DOT Boise's wknd tyke ue ons wo ekaiae man etctek owe ee one ano ern 214 156 58 wae
Proc. Pennsylvania Pharm. Assoc. 1916, p. 119.
115
‘ee $. PHYSIOLOGICAL STANDARDIZATION.
| Millard, E. J.: The U. S. P. has always led the way regarding
| standards and assay methods, and it is not surprising, therefore, to
\ nd biological tests given in detail for cannabis, suprarenal gland,
aconite, digitalis, strophanthus, and squill, and their preparations.—
BPharm. J. 1916, v. 97, p. 36
_ Beringer, George M.: The appearance in the U.S. P. TX of sev-
eral methods fox, the biological assaying of drugs marks the first
| time that assays of this nature have been given recognition by any of
the pharmacopeias.—Am. Druggist, 1916, v. 64, No. 8, p 24,
| Schneider, Albert: The most cori and most concise addition
to Part 2 of the U.S. P. TX is the chapter on biological assays. It is
not clear, however, why the physiological assay for ergot is not in-
eluded; nor is it clear why the assay for cannabis should be compul-
/ sory whereas that for the far more important drug, digitalis, is not
compulsory.—Drug. Cire. 1916, v. 60, p. 693.
Rusby, H. H.: The contribution of the revision committee in the
“way of biological standardization is certainly conservative. The re-
sults accruing therefrom will be awaited with great interest and, by
‘many, with confidence.—Drug. Cire. 1916, v. 60, p. 539.
_ Saylor, W. M.: On the use of plants for the standardization of
drugs. Results showing the effect of strychnine nitrate, tincture of
digitalis and fluid extract of ergot in varying concentrations on the
seedlings of Lupinus albus are given—Am. J. Pharm. 1916, v. 88,
op. 8-12.
Zeigler, W. H.: A criticism of the biologic methods for the stand-
-ardization of digitalis, with a suggestion for a new method. The
fresh-water terrapin, or turtle, is suggested as the test animal.—J.
Am. Pharm. Asoc. 1916, v. 5, p. 1188-1193.
8. PHARMACEUTICAL PREPARATIONS.
Anon.: The highest duty which a pharmacist can perform to
humanity is the omits of medicinally active preparations, and his
“principles and ideals should prevent him from selling any other
-kind.—N. A. R. D. J. 1916, v. 23, p. 193.
® Robin, D. N., and W rh ene T. D.: Two papers urging the
organization of a commission of retail druggists for the purpose of
_ putting on the market a national line of nonsecret remedies.—J. Am.
Pharm. Assoc. 1916, v. 5, p. 695.
Sennewald, E. A.: An article pointing out the financial advan-
tages of making pharmaceutical preparations in the drug store lab-
_oratory.—Meyer Bros. Drug. 1916, v. 37, p. 363.
- Connolly, F. W.: An article pointing out the advantage to the
> “Pharmacist of making his own preparations.—d. Am. Pharm. Assoc.
P1916, v. 5, p. 49.
116
Hilton, S. L.: Saccharin has been eliminated from all N. F. prep.
arations in order to conform to the rulings under the food and
drugs act— Bull. Pharm. 1916, v. 30, p. 281. ad
van der Wielen: A cesar ation of a method for the preparation of
dialysates from fresh digitalis leaves or other fresh plants. Ar
abstract.—Drug. Circ. 1916, v. 60, p. 757.
Marotta, Domenico: In an article dealing with the preparation of
casein and its technical uses, the author describes a number of medice-
inal preparations made therewith.—Ann. chim. applicata, 1916, v.
5, p. 165-176. ;
Anon.: A review of the fifth edition of Caspari’s Treatise on
Pharmacy. The work is stated to have been enlarged and revised in
a manner to bring it in harmony with the new edition of the U. 5.
P.—Bull. Pharm. 1916, v, 30, p. 519.
1. GENERAL FORMULAS.
a)
Beringer, George M.: The instructions of the pharmacopeeial con-
vention to adopt general formulas wherever possible have been par-
tially carried out by the introduction of general instructions for
the preparation of aromatic waters and by the presentation of gen-—
eral formulas and classifications for the fluid extracts and tinctures.—
Am. Druggist, 1916, v. 64, No. 8, p. 24.
Raubenheimer, Otto: An explanation of the “ general formulas ”
for “type processes ” of the U. S. P. for the benefit of pharmacists —
and students of pharmacy.—J. Am. Pharm. Assoc. 1916, v. 5, p.
984-988.
Anon.: A review of the National Formulary states that the type
processes for fluid extracts may and may not be an advantage. If
the type processes are used for the purpose of saving space little
is gained; at least not enough to offset the advantage of having each
formula complete. If, however, the idea is to discredit the fluid
extract and thus to make argument for the addition of the 50 per
cent tinctures in the next revision, then they serve a useful purpose.—
y. A. R. D. J. 1916, v. 22, p. 939.
Zotier, V.: General formulas for the preparation of istonie solu-
tions.—Bull. se. pharmacol. 1916, v. 23, p. 219-225,
2. CHANGES IN STRENGTH.
Scoville, Wilbur L.: A discussion of the changes in strength of —
the galenicals of the U. S. P—Bull. Pharm, 1916, v. 30, p. 323-324.
Beringer, George M.: From a therapeutic standpoint, the changes —
made in the strength of the galenical preparations of the U. S. P.
are, as a rule, negligible. For the most part they have been of minor
importance and are not sufficient to affect either the action or the
dosage of the preparations—Am. Druggist, 1916, v. 64, No. 8, p. 23.
117
Hilton, S. L.: Many of the N. F. preparations have been reduced in
coholic strength for the purpose of eliminating the possibility of
ieir use as beverages. Some of the narcotic preparations have also
en changed so that they come within the exceptions of section 6
f f the Harrison law.—Bull. Pharm. 1916, v. 30, p. 281.
| 3. STANDARDIZATION.
Remington, J. P.: The standards which have been adopted for
he new U. S. P. are reasonably easy of accomplishment, and there
hould be no difficulty in obtaining the official preparations through-
ut the United States. It is not necessary, and it would be extremely
rasteful for the physician to require the absence of all impurities.
Phe Pharmacopeeia sets limits only on certain obnoxious substances,
$ salts of arsenic, mercury, copper, lead, zinc, etc. The presence of
| per cent, more or less, of innoxious salts like the chlorides, sul-
phates, nitrates, etc., within narrow limits, can have no possible
effect in the treatment of any disease.—Proc. Pennsylvania Pharm.
Assoc. 1916, p. 136.
_ Scoville, Wilbur L.: In an article treating of the standardized
preparations of the new edition of the N. F., it is stated that it has
been the purpose of the revision committee to follow established
standards in all articles as far as consistency permitted. Conse-
4. REQUIREMENTS.
Wilbert, M. I.: The change in the nature of the official requirements
4s due to the fact that many critics of the previous edition of the
‘desirability of having a clear, concise definition for each article or
“preparation, with a minimum and maximum limit for the active in-
Hation.—J. Am. Pharm. Assoc. 1916, v. 5, p. eas
' Beringer. George M.: Ina discussion of the U. S. P. as a safeguard
against adulteration, it is stated that it is eee itahte that some of
those who are engaged in the drug business have not yet learned of
“the adequacy of this work and have failed to study its requirements.—
. Am. Pharm. Assoc. 1916, v. 5, p. 603-606.
Rusby, H. H.: It is worthy of note that, in specifying the required
uires that this shall be ae alkaloid or alkaloids of that particular
drug.—Drug. Cire. 1916, v. 60, p. 538
~Diekman, George C.: a of the allowable limits within which
official standards may vary would seem to be too finely drawn. The
118
limits for the camphor content of camphor liniment are cited as a
example.—Pract. Drug. 1916, v. 34, No. 10, p. 25. 4
5. GALENICALS.
Murray, David: In order to arrive at greater simplicity in galent
cals, the author suggests that one definite preparation be made offieig
for each drug, and that all such preparations might be of such ¢
strength that the dose would be from 5 to 15 minims.—Pharm. J
1916, v. 96, p. 190.
Lascoff, J. Leon: A list of the changes in the galenicals of th
U.S. P.and N. F. All of the preparations in which a change occur:
are indicated seriatim.—J. Am. Pharm. Assoc. 1916, v. 5, p. 1112
1117; see also Am. Druggist, 1916, v. 64, No. 10, p. 25-28.
Beringer, G. M.: An enumeration of the reasons for some change
in the fluid extracts and the tinctures of the new U. S. P.—J. A
Pharm. Assoc. 1916, v. 5, p. 1390. ‘a
Diekman, George C.: A general review of the galenicals of
U.S. P. TX, with some remarks on those which were deleted.
Pract. Drug. 1916, v. 34, No. 10, p. 23, 27.
Raubenheimer, Otto: A discussion of the 16 galenicals added to the
U.S. P.—J. Am. Pharm. Assoc. 1916, v. 5, p. 1335-1339,
Lyons, A. B.: In a discussion of the changed alkaloidal standards
in the U. S. P. LX, the author presents a table for adjusting the alke
loidal strength of preparations of the U. S. P. VIII to those of the
U.S. P. EX.—J. Am. Pharm. Assoc. 1916, v. 5, p. 1118-1120.
Heiduschka, A., and Schmid, J.: A report of Investigations deal-
ing with the behavior of certain galenicals toward Fehling’s solu
tion—Chem. Zentralbl. 1916, v. 2, p. 698. 3
Kunz-Krauze, Hermann: A method for the detection of the
minutest quantities of pyridine in galenicals, with special reference
to those which may ae been prepared with denatured a
Chem. Zentralbl. 1916, v. 2, p. 699.
Iischelis, R. P.: In a paper discussing the high price of drugs and
chemicals due to war conditions, the pharmacist is urged to push the
sale of galenical preparations rather than alkaloids, which latter are
stated to be very expensive at present—J. Am, Pharm. Assoc. 1916,
v. 5, p. 411.
6. DETERIORATION.
Caspari, Chas., jr.: Report of the committee on drug deterioration
of the Association of American Dairy, Food and Drug Officials.
Am. Food J. 1916, v. 11, p. 407-408.
Danhauer, William E.: A paper pointing out how a little care in
the handling of drugs and pharmaceutical preparations will resulé
in the saving of many products which are prone to deteriorate.—
Bull. Pharm. 1916, vy. 30, p. 474.
119
Kimmich, E.: A report of investigations to determine the causes
— for the deterioration of elixirs containing iron salts—Canadian
- Pharm. J. 1916, v. 49, p. 223.
~ Congdon, Leon A.: An inspection of the drug stores of Kansas
showed that the fluid extracts on the shelves were deteriorated in
"many instances. A list of names of the deteriorated fluid extracts
‘is given.—Proc. Kansas Pharm. Assoc. 1917, p. 88.
Francis, J. M.: If properly protected from light, contact with air,
and the loss of alcohol, a normal activity may be expected for the
fluid extracts of belladonna leaves or root, ipecac, nux vomica, and
opium for a period of at least three years and in many cases for
five or six years.—Am. Food J. 1916, v. 11, p. 408.
Caspari, Charles, jr.: The deterioration of all galenical prepara-
tions of coca leaves is beyond control in the light of our present
- knowledge concerning the chemistry of the latter—Am. Food. J.
1916, v. 11, p. 407.
Francis, J. M.: Preparations containing glucosides and, to a
lesser degree, those containing alkaloids, are bound to deteriorate
on keeping.—Am. Food J. 1916, v. 11, p. 408.
Anon.: Notes on the decomposition of iodoform ointment and sup-
positories. Iodoform in contact with most fatty products is slowly
decomposed into methylene iodide and iodine. Free exposure to
light, as well as rancidity of the fat, hastens this decomposition.
Moisture-free fats only should be. used—Am. Drug. 1916, v. 64,
No. 8, p. 40.
Editorial: Chloroform is a useful preservative for medicines dis-
pensed in aqueous solution. If used sparingly, it is agreeable to
most persons.—Apothecary (The), 1916, v. 18, No. 9, p. 29.
7. INCOMPATIBILITIES.
Gilmour, J. P.: A discussion of the subject of incompatibility
from the viewpoints of theory and practice. Illustrated with ex-
~emplary prescriptions.—Pharm. J. 1916, v. 96, p. 43-44; Am. Drug-
gist, 1916, v. 64, No. 4, p. 28-30.
Wolfe, J. C., and Lascoff, J. L.: a presentation of 25 prescriptions,
with a discussion of the difficulties encountered in compounding
them.—Am. Druggist, 1916, v. 64, p. 215.
Linton, A. W.: A discussion of a number of incompatibilities,
among which are mentioned some combinations of aspirin with
euquinine in powders or capsules.—Pract. Drug. 1916, No. 10, p. 54.
Anon.: A book review calls attention to a brochure by Thos.
Stephenson entitled Incompatibility in Prescriptions, and How to
Avoid It—Pharm. J. 1916, v. 96, p. 29.
Several authors: Notes on some difficulties encountered in the dis-
pensing of prescriptions.—Am. Druggist. 1916, v. 64, p. 215-216;
see also Brit. & Col. Pharm. 1916, v. 69, p. 156, 330.
120
Astruc, A., and Cambe, J.: Observations on the incompatibility o
sodium bicarbonate with certain salts, especially bismuth. sali-
cylate—J. pharm, et chim, 1916, v. 14, p. 353-356; see a E.
Canals, v. 15, p. 145-149.
Hill, J. Retherford: On the incompatibility of cofutiant of sodiiil
salicylate and iodine——Farm. Espan, 1916, v. 48, p. 488.
Perez, L.: The incompatibility of eatin borate with mercuric
chloride and potassium chlorate—Farm. Espan. 1916, v. 48, p. 25.
8. EXTRACTION.
Mayer, Fritz: A discussion of the importance of ultrafiltration in
the extraction of drugs, with special reference to the clinical action
of holopon, the opium filtrate—Deutsch. med. Wchnschr. 1916, vy. 42,
p. 224-995,
McNair, James B.: An illustrated description of an original type
of extractor which was used successfully in extracting plant mate-
rial with gasoline.—J. Ind. & Eng. Chem. 1916, v. 8, p. 838.
Kippenberger, C.: Illustrated descriptions of several new forms of
extraction apparatus.—Ztschr. angew. Chem. 1916, v. 29, p. 351-852,
359-360,
9. STERILIZATION. | a
Smith, A. R.: Detailed descriptions of methods of sterilization and
preparation of culture media.—Pharm. J. 1916, v. 96, p. 97, 189, 421,
639, and v. 97, p. 234, 294.
Raubenheimer, Otto: The introduction into the National Formu-
lary of a chapter on sterilization is commended in view of its in-
creasing importance in pharmacy and medicine-—D.—A. Apoth.Ztg.
1916, v. 37, p. 78.
Schneider, Albert: The dry heat temperature recommended in the
U. S. P. for the sterilization of glassware, metal utensils, cotton,
bandages, gauzes, and ligatures, is from 160° to 170° centigrade for
two hours. This temperature for that period of time reduces the ten-
sile strength of all cotton fabrics, and of course, can not be applied
to catgut hgatures—Drug. Cire. 1916, v. 60, p. 694.
Hasseltine, H. E.: From experiments, it is concluded that moist
heat is the most effective agent for the sterilization of all metal in-
struments. The method of procedure is described in detail.—Bull.
Hyg. Lab. 1916, No. 101.
Goris, A.: On the preparation and sterilization of catgut fo
surgical use.—Bull. se. pharmaco]. 1916, v. 23, p. 67-81, 141-151.
Corper, H. J.: An illustrated description of an electrical furnace fo
sterilizing innoculating loops.—J. Am. M. Assoc. 1916, v. 66, p. 187.
Penau, H.: A general discussion of the sterilization of water in the
field with special reference to a new method of “ javellisation.”—J.
pharm. et chim. 1916, v. 18, p. 877-885,
121
10. FORMS OF ADMINISTRATION.
_ Becker, M.: A short account of the history and preparation of in-
travenous solutions.—J. Am. Pharm. Assoc. 1916, v. 5, p. 846-847;
see also Rocky Mountain Druggist (The), Denver, 1916, v. 30, No. 4,
p. 11-12.
_ Baldi, Baldo: The technique of preparing solutions for hypodermic
use.—Boll. chim.—farm. 1916, v. 55, p. 161-168.
_ Fantus, Bernard: A discussion of candy medication, including
formule for a number of preparations—J. Am. M. Assoc. 1916, v.
66, p. 26-28.
_ Harman, N. B.: A note on a stable vehicle for use in the prepara-
tion of ophthalmic solutions of alkaloids.—Brit. M. J. 1916, v. 2, p.
178. ,
| Lloyd, John Uri: Colloidal chemistry as applied to pharmaceutical
- problems.—Nat. Eclect. M. Assoc. Quart. 1916, v. 8, p. 34-87.
_ Fisher, Hart E.: An account of experiments in the preparation of
_ a nonadhering surgical gauze.—J. Am. M. Assoc. 1916, v. 66, p. 989-
940.
Dietrich: Formulas for the preparation of adhesives for use in the
| making of surgical dressings.—J. pharm. et chim, 1916, vy. 18, p. 54
from Pharmazevtizeski Journal, 1915, p. 386.
AMPOULES.
| J. J. H.: A book review of a small volume by Hans Freund on
- the manufacture of ampoules. The pamphlet is entitled Die Am-
pullenfabrikation in ihren Grundzigen dargestellt—Chem. Week-
blad, 1916, v. 13, p. 1164; see also Schweiz. Apoth.-Ztg. 1916, v. 54,
p- 605.
Krebére: A report of experiments to determine the alkalinity of
the glass in ampules. The most sensitive reagents in their order of
sensitiveness are salts of narcotine, strychnine, phenolphthalein, and
morphine.—Répert. pharm. 1916, v. 28, part 1, p. 210 from Pharma-
_ zevtizeski J. 1915, p. 385.
Paul, Theodore: A discussion of the changes which take place in
- liquid medicaments when kept in glass containers. In order to
prevent these changes, the use of separate ampules for liquids and dry
_ materials is recommended.—Siidd. Apoth.-Ztg. 1916, v. 56, p. 459-460.
Davis, R. G.: An illustrated description of an apparatus for filling
- yaecine ampules.—U. 8S. Naval Med. Bull. 1916, v. 10, p. 311-813.
_ Vieario, A.: An illustrated description of an ampoule containing
solution of iedine and intended for use by the individual in emer-
gency cases where an antiseptic is needed.—J. pharm. et chin. 1916,
» vy. 13, p. 49-51.
122
CAPSULES.
Scoville, W. L.: A description of a method for the preparation of
enteric capsules by the immersion of ordinary gelatin capsules im a 1
per cent solution of formaldehyde.—Bull. Pharm. 1916, v. 30, p. 76.
Davis, N. S.: For administering deliquescent drugs and certain:
liquids, it is suggested that they be incorporated in a wax mass con-
sisting of 1 part beeswax and 3 parts of castor oil and the whole dis-
pensed in capsules of the desired size.—J. Am. M. Assoc. 1916, v. 67,
p. 1160.
Griffith, Ivor: A description of a simple method for filling soft
capsules.—Am. Druggist, 1916, v. 64, No. 8, p. 26.
COMPRESSED TABLETS.
Francois, M.: A criticism of compressed tablets as a form of medi-
cation.—J. pharm. et chim. 1916, v. 13, p. 241. .
Voiry, R.: A general discussion of compressed tablets under the
captions “manufacture,” “analysis of,” “advantages and disad-
vantages,” ete.—J. pharm. et chim. 1916, v. 14, p. 177-182.
Fantus, Bernard, and Snow, Clyde M.: A short paper discussing
methods for the extemporaneous preparation of tablets—J. Am.
Pharm. Assoc. 1916, v. 5, p. 147-149.
Lieungh, Frode: Formulas and directions for the preparation of
a number of different kinds of tablets are given.—Norges Apotek.
Tidsskr. 1916, v. 24, p. 69-74.
Street, John Phillips: Tables are given showing the variation im
the weights of tablets, variation in the amount of medicament present,
etc.—Rep. Connecticut Agric. Exper. Sta. 1916, part 4, p. 249-255.
Clampett, G. W.: Analytical data showing the variation of active
ingredients in tablets of mercuric iodide, calomel, corrosive subli-
mate, trinitrin, and extract of nux vomica.—Proc. Texas Pharm.
Assoc. 1916, p. 81.
11. METHODS OF ADMINISTRATION.
Macht, David I.: The history of the intravenous and subeutaneous
methods of administering medicines. For hypodermic injections,
the Pravaz syringe was first employed and is the model which the
present manufacturers have copied and modified.—J. Am. M. Assoe.
1916, v. 66, p. 856-860.
Vadam, Ph.: A brief note on the history of the development of
hypodermic medication.—Bull. se. pharmacol. 1916, v. 23, p. 3382-337.
Fowler, W. N.: An illustrated description of the procedure to be
employed in administering drugs intravenously.—Am. J. Clin. Med.
1916, v. 23, p. 570-5738.
Hirsch, Charles T. W.: An illustrated description of a et per-
centage chloroform inhaler.—Lancet, 1916, v. 190, p. 730
Il. INTERNATIONAL STANDARDS.
1. THE EVOLUTION OF UNIFORMITY IN PHARMACOPGIAL
STANDARDS FOR POTENT MEDICAMENTS.
1. ADOPTION OF BRUSSELS CONFERENCE PROTOCOL.
Du Paul, A. M.: In the U.S. P. UX, after some of the synonyms
will be found the capital letters P. L., which stand for “ Protocol
International,” and mean that the drug or preparation is in harmony
with the national standards adopted by the Brussels Conference,
September, 1902.—Apothecary, 1916, v. 13, No. 9, p. 30.
Beringer, George M.: A number of the variations in the U. S. P.
standards and those of the international protocol are discussed for
_ the purpose of showing the reasons for our inability to conform to
all of the requirements of the latter—Am. Druggist, 1916, v. 64, No.
8, p. 23.
Scoville, W. L.: A brief comment on the U. S. P. LX, with re-
spect to the influence of the Brussels Conference protocol—Bull.
Pharm. 1916, v. 30, p. 279.
Sayre, L. F’.: An enumeration of the additions to and deletions
from the new U. S. P., with a discussion of the agreements with
and deviations from the recommendations of the Brussels Confer-
~ ence.—Pharm. Era, 1916, v. 49, p. 306 and 355.
2. FOREIGN PHARMACOP@GIAS.
Forrester, G. P.: A table illustrating the wide divergence existing
in current pharmacopeias.—Yearbook of Pharmacy (and Trans-
actions of the British Pharmaceutical Conference), London, 1916,
p. 378-379.
1. BRITISH.
Anon. A criticism of the Ph. Brit. directions for the prepara-
tion of dilute acids——Chem. & Drug. 1916, v. 88, p. 462.
Anon.: A review of the nineteenth edition of Squires’? Companion
to the British Pharmacopwia (1914). The arrangement of the sub-
ject matter is stated to be the same as in previous editions. All
parts of the work have been thoroughly revised and much new ma-
terial added. The paragraphs on medicinal properties, foreign phar-
macopeeias, and tests are stated to be especially complete.—Am. J.
Pharm. 1916, v. 88, p. 373-376.
Anon.: A book review calls attention to the completeness of the
_ tables of physical constants in the nineteenth edition of Squires’ Com-
(123)
124
panion to the British Pharmacopwia.—Chem. & Drug. 1916, v. 88,
No. 1905, p. 770.
Anon.: A book review of the tenth edition of a volume by Chas. Fr
Heebner entitled A Synopsis of B. P. Preparations.—Canadian |
Pharm. J. 1916, v. 49, p. 326. f
Anon.: A Fuge review calls attention to the ninth edition of a vol-
ume by Wippell Gadd entitled A Synopsis of the British Pharma-
cope@ia, 1914, and of the Poison Laws of Great Britain and Ire-"
land.—Pharm. J. 1916, v. 97, p. 419. .
2. DUTCH.
Moll, J. W.: Comments on the descriptions of the simples of the —
Ph. Ndl.—Pharm. Weekblad, 1916, v. 53, p. 1401-1416, 1438-1452,
Anon.: A review of the second supplement to the fourth edition
of the Ph. Nd].—Farm. Espan. 1916, v. 48, p. 641-644, 657-659.
Anon.: A discussion of the methods as given in ii supplement —
to Ph. Ndl. IV for assaying collargol and protargol Schweiz.
Apoth.-Ztg. 1916, v. 54, p. 340.
3. GERMAN.
Anon.: A book review cadls attention to a supplement to the Ph.
Germ. edited by the Deutschen Apotheker-Verein. The volume is
entitled Erganzungsbuch zum Areneibuch fur das Deutsche
Reich—Pharm. Weekblad, 1916, v. 53, p. 1428.
4. ITALIAN.
Lami, Pio: Notes on some of the chemicals and preparations of
the third edation of the Ph. Hal ariel: Late ‘farm. 1916, v. 55, p.
p- 3 6, 99- 102.
5. SPANISH.
Anon. : Additions to and corrections of the seventh edition of the’
Spanish pharmacopeia—Farm. Espan. 1916, v. p. 48, p. 149-150.
III. COMMENTS ON OFFICIAL ARTICLES.
ABSINTHIUM, N. F.
Anon.: A short note giving information relative to the cultivation
of wormwood in America.—N. A. R. D. J. 1916, v. 21, p. 805.
ACACIA.
_ Waters, C. E., and Tuttle, J. B.: Descriptions of some qualitative
ests for gum arabic and a method for its quantitative determination.—
Tech. Papers Bur. Stand. 1916, No. 67, p. 1-15; see also J. Ind. &
Eng. Chem. 1916, v. 8, p. 413-416.
Savini, G.: A report of investigations dealing with the deter-
mination of sugar in preparations containing acacia.—Ann. chim.
Sapplicata, 1916, v. 6, p. 250-255.
ACETANILIDUM.
. Broeksmit: A comparison of the reactions of acetanilid, phe-
-nacetin, pyramidon, and other similar compounds. An abstract.—
Drug. Cire. 1916, v. 60, p. 86.
Salkover, Benedict: A description of a quantitative method for
| determining salol and acetanilid in mixtures of the two, also salol
‘and acetphenetidin in their mixtures. The method is based on the
difference in the solubility of these substances in petroleum ether.—
‘Am. J. Pharm. 1916, v. 88, p. 484-485.
'E’we, G. E.: A sample of acetanilid examined left 0.23 per cent
“residue upon ignition, but was otherwise U. S. P.—Proc. Pennsyl-
-yania Pharm. Assoc. 1916.
Anon.: A criticism, from the therapeutic standpoint, of formulas
for compound solutions of acetanilid.—J. Am. M. Assoc. 1916, v. 66,
ep. 1199.
’ ACETONUM.
Darrin, M.: A description of the electric-furnace method of pro-
“ducing acetone from pyroligneus acid.—J. Ind. & Eng. Chem. 1915,
i, p. 927-929.
' White, A. H.: U.S. Patent No. 1,197,983. A method for the manu-
facture of acetone and methyl] alcohol from the waste liquor of soda
wood pulp.—Chem. Abstr. 1916, v. 10, p. 3160.
Bayer & Co.: German Patent No, 283,107. A method for obtain-
ing acetone and alcohol by fermenting sugar and materials contain-
| ing sugar is described.—Chem. Abstr. 1916, v. 10, p. 661; see also p.
953 and 1407.
(125)
126
Rakshit, Jitendranath: A method for the estimation of acetone in
the presence of ethyl] aleohol—Analyst (The), 1916, v. 41, p. 945-946.
Frankforter and Cohen: The determination of acetone in systems
of methyl] alcohol water, and potassium fluoride; and equilibria inv
systems of methyl-ethyl ketone, water, and inorganic salts——J. Am.
Chem. Soc. 1916, v. 38, p. 1136-1141.
E’we, G. E.: One lot of acetone examined contained excessive
empyreumatie substances, but was otherwise U. S. P._—Proec. Pennsyl-
vania Pharm. Assoc. 1916.
ACETPHENETIDINUM.
Broeksmit: A comparison of the reactions of acetanilid, phenac-
etin, pyramidon, and other similar compounds. An Abstract.—
Drug. Cire. 1916, v. 60, p. 86.
Salkover, Benedict: A description of a quantitative method for
determining salol and acetanilid in mixtures of the two, also salol
and acetphenetidin in their mixtures. The method is based on the
difference in the solubility of these substances in petroleum ether.—
Am. J. Pharm. 1916, v. 88, p. 484485.
Hostmann, Jeannot: Fifteen 5-grain powders were examined.
Three responded to the test for acetanilid and one contained sugar
of milk—Proc. Nebraska Pharm. Assoc. 1916, p. 78.
Reverdin, Frédéric, and Lolkietek, J.: The preparation and
properties of m-phenetidine and some of its derivatives.—Bull. Soe.
chim. France, 1916, v. 19 and 20, p. 252-259.
Amory, W. O.: Researches on the periodides of phenacetine,
methacetine, and trophenine.—J. Am. Chem. Soc. 1916, v. 38, p. 140.
ACETA.
Joltze: Attention is called to the difficulty of filtering Aceta Saba-
dillae, and suggestions for overcoming this difficulty are given. An
abstract.—C. U. C. P. Alumni J. 1916, v. 23, p. 118.
ACIDUM ACETICUM.
Takahasi, E.: The author’s experiments demonstrate that Fucus
evanescence, a seaweed growing along the coast of Kokkaido, will
ferment with the production of acetic acid if allowed to stand with
water and a little lime—Chem. Abstr. 1916, v. 10, p. 806 from J.
Chem. Ind. Japan, 1916, v. 19, p. 30-41.
Harburger, Chem. Fabrik.: Danish Patent No. 21175. A method
for obtaining concentrated acetic acid consists of distilling the dilute
acid with potassium acetate—Chem. Abstr. 1916, v. 10, p. 2028.
Heermann, P.: A method for the separation of acetic and formie
acids is based on the quantitative replacement of acetic acid with —
127
pure formic acid—Chem.-Ztg. 1915, v. 39, p. 124; Chem. Abstr. 1916,
10, p. 2080.
Selingman, R., and Williams, P.: An account of the action of
boiling acetic and other organic acids on aluminum.—J. Soc. Chem.
d. 1916, v. 35, p. 88-93.
_ Salkowski, E.: Data are presented showing that Cu, Ag, Hg, Pb
and Bi will dissolve in acetic acid containing hydrogen dioxide.—
J. Soe. Chem. Ind. 1916, v. 35, p. 741 from Chem. Ztg. 1916, v. 40,
p. 448-449.
Szeberanyi: A method for the detection of formic acid in acetic
acid. The test depends on the power of formic acid to reduce chro-
mium trioxide in boiling solution, while acetic acid has no effect
| under the same conditions.- An abstract—Pharm. Era, 1916, v. 49,
p. 276.
Congdon, Leon A.: One sample of acetic acid examined was re-
| jected.—Rep. Kansas Bd. Health, 1916, p. 133.
ACIDUM ACETYLSALICYLICUM (NONOFFICIAL).
Tsakalotos, D, E.: A discussion of the physical and chemical prop-
erties of aspirin which may be of use in the identification of the
same.—J. pharm. et chim. 1916, v. 14, p. 174-177.
. Tsakalotos, D. E., and Horsch, S.: A report of researches on
aspirin. IV. Tlustrated descriptions of the concentric rings formed
_ by melted or dissolved aspirin upon solidification.—Bull. soc. chim.
_ France, 1916, v. 19 and 20, p. 321-3826.
_ Parry, E. J.: After reviewing the work of Tsakalotos and Horsch,
the author concludes that the melting point of acetylsalicylic acid
as given in the Ph. Brit. (136-137° C.) is not too high.—Chem. &
- Drvig. 1916, v. 88, p. 611.
Snyder, J. P.: An enumeration and description of tests for the
identity and purity of acetylsalicylic acid—J. Am. Pharm. Assoc.
1916, v. 5, p. 756-758.
Matson, G. N.: A description of a method for the quantitative
determination of free salicylic acid in aspirin.—Drug. Cire. 1916,
v. 60, p. 7.
_ Anon.: An article pointing out the danger of the formation of the
toxic compound, quinotoxin, when quinine is dispensed with
_ aspirin.—Pharm. J. 1916, v. 97, p. 27.
af Klercker, O.: A report on 20 cases which showed a marked
idiosyncrasy to therapeutic doses of acetylsalicylic acid. An ab-
stract.—J. Am. M. Assoc. 1916, v. 66, p. 1282.
Lea, E. J.: More than one-half of the samples of aspirin exam-
ined were imitation products, some containing no aspirin at all.—
Bull. California Bd. Health, 1916, v. 11, p. 361.
128
Sayre, L. E.: Samples of aspirin examined contained acetanilid
salicylic acid, sugar, starch, and inorganic salts—Bull. Kansas Bi
Health, 1916, p. 8.
Paris letter: Some of the pharmacists in Paris, France, have
cently been supplied with a substitute for powdered aspirin,
which, upon examination, was found to contain no acetylsalicylic
acid—J. Am. M. Assoc. 1916, v. 66, p. 522.
Frary, Guy G.: One sample of aspirin capsules examined was re-
jected as the capsules contained only 4.37 grains of the drug, whereas
they were labeled 5 grains.—Rep. South Dakota F. & D. Com. 1916,
No. 16, p. 150. ‘
Lea, E. J.: The examination of aspirin tablets and capsules shows
that they are still often highly adulterated—Bull. California Bd.
Health, 1916, v. 11, p. 536.
Bonjean, Ed.: Of 10 lots of aspirin tablets of French commerce
examined. 4 contained less than the indicated dose, 2 being entirely
destitute of J. pharm. et chim. 1916, v. 14, p. 19; see also-
Ann. Falsif. 1916, v. “9, p. 169-175.
Table showing some of the analytical results reported for aspirin tablets.
1
t Number of samples—
Reporters. | References.
é , Examined.| Rejected.
HarnNgra. eds een eee eS
28 4 | Bull. Indiana Bd. Health; 1916, v. 19, P- 39, 136.
Congdon, Leon A............. 2 1 Rep. Kansas Bd. Health, 1916, p
Eskew, Harry L.............- 59 20 Rep. Tennessee F. & D. Dept. 1, A 16.
Harms, Herman.............- &6 6 Rep. Utah D. & F. Com. 1916, p. 9.
EE a (ORs SR En aie 4 4 Bull. California Bd. Health, 1916, 4 12, p . 112,
Noda. PA Roses eet hce eee 2 1 Bull. Michigan D. & F. Dept. 1916, No. Sou,
a p. 20.
Waiedemann, Ey P2505 sss sce 16 5 Rep. Missouri F. & D. Com. 1916, p. 16.
7 2 Proc. Missouri Pharm. Assoc. 1916, p. 30.
Wihitney; Mrs. Dy V.i22--2-2. |
|
—
|
ACIDUM BENZOICUM.
Grossfeld, J.: A useful modification of the so-called Mohler re-
action of benzoic acid is described.—Chem. Abstr. 1916, v. 10, p. 225
from Ztschr: Unters Nahr.- u. Genussm. 1915, v. 30, p. 271-278.
Tentative methods for the quantitative determination of benzoic
acid and other substances in foods are presented—J. Assoc. Off.
Agric. Chem. 1916, v. 2, part 2, p. 83-86.
Held, Dirk: A presentation of experimental data pertaining to
the preservative properties of benzoic acid.—Chem. Abstr. 1916, v. 10,
p. 2358.
Umney, J. C.: A report on grass tree gum or acaroid resin as a
source of benzoic acid.—Chem. Abstr. 1916, v. 10, p. 951 from Perf.
& Ess. Oil Rec. 1915, v. 6, p. 212.
129
| Stadiain, W.: A report of investigations relating to the deter-
mination of benzoic acid in fats.—Chem.-Ztg. 1916, v. 40, p. 770,
Roberts, J. G.: Six casks of benzoic acid examined contained from
4.5 to 24.5 per cent of boric acid.—Proc. Pennsylvania Pharm. Assoc.
ACIDUM BORICUM.
Halphen, G.: A description of a colorimetric method for the deter-
mination of minute quantities of boric acid—aAnn. chim. analyt.
1916, v. 21, p. 2-3.
Vanzetti, B. L.: Researches on the constitution of ammonium
salts of boric acid.—Chem. Abstr. 1916, v. 10, p. 575.
ACIDUM CITRICUM.
Anon.: On the industrial production of citric acid—Farm. Espan.
| 1916, v. 48, p. 853-356, 369-373.
fe Martin, John Albert: On the production of citric acid by means of
fungi of the Ascomycetes group—Am. J. Pharm, 1916, v. 88, p.
837-355.
Willaman, J. J.: A modification of the Pratt method for the
Broeksmit, T. C. N.: A discussion of methods for the detection of
citric acid in foods and medicines, The precipitation of barium
itrate was used by the author as a preliminary test and the iodoform
test as confirmatory for the presence of citric acid.—Pharm. Week-
blad, 1916, v. 53, p. 1034-1037.
ACIDUM HYDROBROMICUM DILUTUM.
ACIDUM HYDROCHLORICUM.
Thelen and Wolf: A furnace for making sodium sulphate and
hydrochloric acid. U. S. Patent No. 1,165,815, Dec. 28—Chem.
Abstr. 1916, v. 10, p. 670.
- Ellis, J. H.: A report on the chemical activity of the ions of
hydrochloric acid as determined by electromotive force measure-
ments.—Proc. Nat. Acad. Sci. 1916, v. 2, p. 83-87.
_ Richards, T. W., and Harris, G. W.: The authors have plotted
curves from a study of the floating equilibria. These curves, they
‘state, may be used with the aid of a standard thermometer to analyze
‘solutions of hydrochloric acid——J. Am. Chem. Soc. 1916, v. 38, p.
1000-1001.
110095°—19 9
130
Christiansen, Johanne: A polemic with O, Krummacher on thie
use of indicators in the testing of medicimes for hydrochloric acid.
Chem. Abstr. 1916, v. 10, p. 913 from Ztschr. Biol. 1915, v. 65, p.
513-515.
Long, J. H., and Hull, Mary: Researches with respect to the
combination of protein with halogen acids.—Rep. Therap. Res. Com.
1916, v. 5, p. 5-21. .
Todd, A. R.: One sample of hydrochloric acid examined was re-
jected —Bull. Michigan D. & F. Dept. 1916, No. 244-247, p, 20.
ACIDUM HYDROCHLORICUM DILUTUM.
Sayre, L. E.: A sample of dilute hydrochloric acid examined”
was above standard.—Bull. Kansas Bd. Health, 1916, p. 11.
Congdon, Leon A.—One sample of diluted hydrochlorie acid
examined was rejected.—Rep, Kansas Bd. Health, 1916, p. 183.
Anon.: Of five samples of dilute hydrechlorie acid examined, two
were not of U. S. P. strength——Proe. Minnesota Pharm. Assoc. 1916, —
p. 211.
ACIDUM HYDROCYANICUM DILUTUM.
Scoville, Wilbur L.: The diluted hydrocyanic acid of the U.S. PA
LX contains a little hydrochloric acid—not more than 0.1 per cent—_
which tends to make the solution more stable—Bull. Pharm. 1916, —
v. 30, p. 362.
Dott, D. B.: Notes on the determination of hydrocyanie acid by —
the methods of the old and the new editions of the British pharma-
coporia.—Pharm. J. 1916, v. 96, p. 368.
Anderson, G.: A report of experiments to determine the sensitivity
of the common qualitative methods for the detection of hydrocyanic
acid.—Ztschr. anal. Chem. 1916, v. 55, p. 459-468. BY
Johnson, Maxwell O.: A description of a method for the deter-—
mination of small quantities of hydrocyanic acid.—J. Am. Chem. ~
Soc. 1916, v. 38, p. 1230-1235,
ACIDUM HYPOPHOSPHOROSUM.
Kolthoff, J. M.: From an examination of the various methods —
recommended for the determination of the hypophosphites, it is
concluded that oxidation with Koppeschaar’s solution and titration —
of the excess of bromine iodometrically is the most convenient.— —
Pharm. Weekblad, 1916, v. 53, p. 909. %
Marriott, W. M.: It has been demonstrated that the hypophos- —
phites do not influence any pathological process. They are’ not
foods. If they are of any use, that use has never been discovered.—_
J. Am. M. Assoc, 1916, vy. 66, p. 486.
151.
E’we, G. E.: Two lots labeled“ Hypophosphorus acid 10-11 per
cent” contained 8.55 per cent and 8.60 per cent, respectively.—Proc.
ennsylvania Pharm. Assoc. 1916, p. 113.
ACIDUM LACTICUM.
Scoville, Wilbur L.: The Pharmacopeia now recognizes the pres-
ence of the lactide, and in consequence thereof has made the standard
for lactic acid 85 to 90 per cent of total acid instead of 75 per cent
‘of free acid—Bull Pharm. 1916, v. 30, p. 362.
_ Anon.: A detailed outline of methods for the analysis of lactic
acid.—Chem. Eng. 1916, v. 23, p. 124-125.
Thomas, Stanley J.: A study of the stereo-isomerism of fermenta-
tion lactic acid —J. Ind. & Eng. Chem. 1916, v. 8, p. 821-823.
Paladin and Sabinin: On the decomposition of lactic acid by
killed yeast.—Chem. Abstr. 1916, v 10, p. 1356, from Bull. acad. sci.
Petrograd, 1916, p. 187-194.
ACIDUM NITRICUM.
i. Withrow, James R.: A discussion of analytical data relative to the
‘sophistication of nitric acid with sodium nitrate and other sodium
salts. —Trans. Am. Inst. Chem. Eng. 1916, v. 9, p. 297-817.
: ACIDUM NITROHYDROCHLORICUM.
fy Briner, E.: A study of the reactions involved in the production
of nitrohydrochloric acid. An abstract—Chem. News, 1916, vy. 113,
‘—p. 215.
. ACIDUM OLEICUM.
_ Fahrion, W.: A detailed account of our present knowledge of the
chemical constitution of the oleic acids, 16 of which are possible ac-
cording to theory. The 11 known oleic acids and the 3 known
-stereoisometric elaidin acids are described.—Chem. Abstr. 1916, v. 10,
?p. 1278, from Chem. Umschau, 1916, v. 23, p. 2-8.
ie ACIDUM PHOSPHORICUM.
3 Serger, W.: A description of a nephelometric method for the
‘determination of small quantities of phosphoric acid—Pharm.-Zte.
1916, y. 61, p. 114.
F Balareff, D.: A description of an acidimetric method for the de-
termination of phosphoric acid.—Ztschr. anorg. Chem. 1916, v. 97, p.
7.
ACIDUM SALICYLICUM.
Obregén Garcia, J. G.: Notes on the chemistry of salicylic acid
and the E Meviates —Farm. Espan. 1916, v. 48, p. 200-201.
_ Smith, H. L.: The true melting point & salicylic acids is 168.5° C.
Pure parahydroxybenzoic acid melts at 213.5° C., but its presence
i
&
e.
132
in salicylic acid lowers the melting point of the latter. Salicyl
acid containing 1 per cent of parahydroxybenzoic acid melts at 155°
to 156° C.—Analyst, 1916, v. 41, p. 3-6. ris
Arny, H. V., and Ring, C. HL: A report of colorimetric tests for
solutions of salicylic acid——J. Ind. & Eng. Chem. 1916, v. 8, p.
StG=317: | 4
Watson, G. N.: A description of a method for the quantitative
determination of salicylic acid in the presence of acety age acid.
The method described is essentially a modified Freyer’s method.—
Drug. Cire. 1916, v. 60, p. 7: see also Chem. Abstr. 1916, v. 10, p. 801,
Rocques, X.: A description of a method for the detection of
salicylic acid in wine—Ann. chim. analyt. 1916, v. 21, p. 117-118. —
Claasz. M.: A report of investigations on the nature of the re-
action which takes place between ae acid and ferric chloride.—
Chem. Abstr. 1916, v. 10, p. 2214, from Arch. Pharm, 1915, v. 253,
p- 360-366.
Editorial: The action of salicylic acid is comparable in many
ways with its chemical relative. phenol, or carbolic acid. It is irritat-
ing to tissues and it functions as a protoplasmic poison—2J. Am,
M. Assoc. 1916, v. 66, p. 122.
ACIDUM STEARICUM.
Jacobson, C. A., and Holmes, August: Solubility data for various”
salts of laurie, myristic, palmitic, and stearic acids.—J. Biol. Chem.
1916, v. 25, p. 29-53.
Holland, E. B., Reed, J. C., and Buckley, J. P., jr.: A report
of experimental researches on the determination of stearic acid in
butter fat—2J. Agric. Research, 1916, v. 6, p. 101-113.
ACIDUM SULPHURICUM.
Editorial: Sulphuric acid in America. A review of a paper by
Waggaman on “The production of sulphuric acid and a proposed _
new method of manufacture.”—Nature, 1916, v. 97, p. 60-61.
Martenet, S. J.: Some notes on the designing of sulphuric acid
plants—Chem. Abstr. 1916, v. 10, p. 2389, from Chem. Eng. Manufr,
1916, v. 24, p. 33-34.
Elektrizitatswerk Lonza: A process for obtaining sulphurie acid
from gypsum and quartz. Swiss Patent No. 72.627, June 2.—Chem.
Abstr. 1916, v. 10, p. 2391. ; -
Fairhe, Andrew M.: A description of a new method for the con-
tal of the camber ee for making sulphuric acid—Trans. Am.
Inst. Chem. Eng. 1916, v. 9, p. 319-338. iN
For patents relating te the manufacture of sulphuric acid’ see
Chem. Abstr. 1916, v. 10, and J. Soe. Chem, Ind. 1916, v. 35.
133
_ Sidersky, D.: A new table showing the relation of density to con-
eentration of sulphuric acid.—Ann. chim. analyt. 1916, v. 21, p.
197-198.
_ Holler and Pfeffer: The density of aqueous solutions of copper
sulphate and sulphuric acid.—J. Am. Chem. Soc. 1916, v. 38, p.
- 1021-1029; see also Chem. Abstr. 1916, v. 10, p. 1453.
_ E’we, G. E.: The arsenic in the commercial sulphuric acid tested
_ during the past year has kept within the U. S. P. limit for arsenic
in U.S. P. acid.—Proc. Pennsylvania Pharm. Assoc. 1916, p. 118.
Donk, A. D.: Experimental data showing the amount of lead sul-
phate present at different temperatures in the system, lead sulphate,
sulphuric acid and water—Chem. Weekblad, 1916, v. 13, p. 92-97.
Schmidt, Ernest: A study of the different methods for the detec-
tion of minute quantities of seleneous acid in sulphuric acid—Ann.
mralsif. 1916, v. 9, p. 475.
_ Gyzander, C. R.: Notes on the titration of sulphuric acid.—Chem.
News, 1916, v. 114, p. 260-261.
Zinker, W.: The action of sulphuric acid in dissolving cellulose.—
Chem. Abstr. 1916, v. 10, p. 971 from Kunstoffe, 1916, v. 6, p. 4-7,
19-20. |
b ACIDUM SULPHURICUM AROMATICUM.
Penniman, Randall, Miller, and Enslow: A description of a
method for determining the total sulphuric acid in aromatic sul-
Chem. 1916, v. 8, p. 904-909.
ACIDUM SULPHURICUM DILUTUM.
ACIDUM TANNICUM.
Dekker J.: A discussion of the significance of tannin in the make-
Frary, Guy G.: All of the 11 samples of tannic acid examined for
ash content were passed.—Rep. South Dakota FI. & D. Com. 1916,
134
Anon.: Experiments conducted in Germany show that a 5 per cent
solution of tannin in alcohol is a good substitute for tincture o:
iodine.—Chem. & Drug. 1916, v. 88, p. 38.
ACIDUM TARTARICUM.
Baekland and Peter: A method for the electrolytic production of
tartaric acid. U. S. Patent No. 1,190,485, July 11—Chem. Abstr.
1916, v. 10, p. 2173.
Hartmann, B. G., et al.: Researches on the quantitative determima-
tion of tartaric acid—J. Ind. & Eng. Chem. 1916, v. 8, p. 422-425.
Carles, P.: Notes on some irregularities observed in the determina-
tion of tartaric acids in lees and tartars.—Répert. pharm. 1916, v.
28, part 1, p..0-—4.
ACIDUM TRICHLORACETICUM.
Vanderkleed, C. E.: None of the samples of trichloracetie acid
examined gave a faint reddish color with ferric chloride as required
by the U. S. P., but even reagent acids refused to conform to this:
test.—J. Am. Pharm. Assoc. 1916, v. 5, p. 536.
ACONITINA.
Tunmann, O.: In a series of articles dealing with the microchemical —
analysis of drugs, the first article is devoted principally to a discus-_
sion of the detection of aconitine in toxicological cases.—Pharm.—Ztg. ~
1916, v. 60, p. 49. |
ACONITUM.
Danesi, Dario: Note on the International Pharmacopoeia. A com-
parative study of aconite in the light of the Italian, German, English, —
and French pharmacopeias.—Boll. chim.farm. 1916, v. 55, p. 417—
421.
Kourrote: A report of a study of Aconitum orientale and A. napel-
lus gathered in Russia.—J. pharm. et chim. 1916, v. 13, p. 328-3829
from Pharmazevtizeski J. 1916, p. 76.
Fraser, Thomas R.: A contribution to the pharmacology of Aconi-—
tum heterophylloides, Aconitum nagarum, and Aconitum napellus.—_
J. Pharmacol. & Exper. Therap. 1916, v. 9, p. 43-56.
Achard, H. J.: A clinical study of aconite, its alkaloids and pre-
parations.—Am. J. Clin. Med. 1916, v. 23, p. 1004-1006.
Roberts, J. G.: All samples of aconite root examined were U.S. P. ©
with the exception of one, which was wormy and dirty.—Proe. Penn- —
sylvania Pharm. Assoc. 1916.
Vanderkleed, C. E.: Of five samples of aconite root examined, the
highest alkaloidal content observed was 0.626 per cent and the low-
est 0.360 per cent.—J. Am. Pharm. Assoc. 1916, v. 5, p. 536,
135
| E’we, G. E.: Of 11 samples of aconite root assayed, the aconi-
tine content of two was above standard, and in nine samples, it was
below standard.—Proc. Pennsylvania Pharm. Assoc. 1916, p. 119.
_ Anon.: The aconitine content of four samples of aconite leayes as-
sayed was above standard.—Proc. Pennsylvania Pharm. Assoc. 1916,
p. 119.
+ ADEPS.
| Parry, Ernest J.: A modified Becchi test is given in the U. S. P.
for this fat to preclude the presence of cotton seed fats. The test, un-
less accompanied by quantitative tests for the adulterant is worth-
less, as the fat from hogs fed on cotton cake often gives a marked
Becchi reaction.—Chem. & Drug. 1916, v. 88, No. 1913, p. 40.
_ Anon.: G. M. Arrowsmith finds that lard may be prevented from
_ becoming rancid by immerging a small bottle of formalin in it. A
small glass tube is inserted through the cork of the bottle and is of
sufficient length to just project above the surface of the lard.—Bull.
| Pharm. 1916, v. 30, p. 123.
Koester: A formula, with directions, for the preparation of a lard
substitute, —Pharm. Zentralh. 1916, v. 57, p. 254.
*.
i ADEPS BENZOINATUS.
_ Williams, Ed. E.: A modification of the U.S. P. process for mak-
ing benzoinated lard is described.—Am. Druggist, 1916, v. 64, No. 3,
?P. 25.
ADEPS LANZ.
_ Ayers, E. E.: A discussion of methods for the recovery of wool fat.
_A centrifuge for this purpose is stated to be on the market at this
time. —Chem. Abstr. 1916, v. 10, p. 1278 from Met. Chem. Eng. 1916,
_v. 14, p. 317-818.
_ Swift, E. G.: Wool fat of medicinal quality is difficult to obtain.
mit is astiatly dark in color and strong in odor, and frequently shows
‘an excess of sulphur compounds.—Oil, Paint & Drug Rep. 1916,
_ y. 90, No. 16, p. 46.
— Rohmann, F.: Analytical data dealing with the constitutents of
B00! fat.—Biochem. Ztschr. 1916, v. 77 2B. 298-328.
Richardson, F. W., and Bracewell, G. A.: A discussion of the an-
_ alysis of waxes, with special reference to eda and wool wax.—
a. Soc. Chem. Ind. 1916, v. 35, p. 160-163.
3 Roberts, J. G.: Two samples of the American product were found
to be aieiiarated with petrolatum; 15 samples were found to contain
- 2 to 12 times as much acid as allowed by the U. S. P.—Proe. Pennsyl-
~ yania Pharm. Assoc. 1916, p. 108.
a 2 Pee
136 7
Lilly, J. K.: Some of the samples of wool fat examined were found
to be adulterated with lard stearin——Oil, Paint & Drug Rep. 19146,
y. 90, No. 16, p. 46. :
Deseriptions of various substitutes for wool fat—Chem. & Drug
1916, v. 88, p. 341; see also Schweiz. Apoth.-Ztg. 1916, * 54, p. 33.
ADONIS.
Lilly, J. K.: One lot of Adonis annua was offered as true Adonis
vernalis —Oil, Paint & Drug Rep. 1916, v. 90, No. 16, p. 46.
AETHER.
Kirby, H. A.: A reprint of a portion of a thesis on the history
of anesthetics giving an account of the early use of ether for pro-
ducing anesthesia.—Drug. Cire. 1916, v. 60, p. 749-751. ‘
Mallinckrodt, Edward, jr.: Doubt is expressed as to the ability to
prepare ether by the usual process of distillation which will comply:
strictly with the requirements of the present Pharmacopeeia. Meth-
eds for determining small amounts of alcohol and water in ether
are described.—J. Ind. & Eng. Chem. 1916, v. 8, p. 807-812.
Seoville, Wilbur L.: Owing to the tendency of ether to oxidize
in containers from which a part of the contents has been removed,
the Pharmacopeia now specifies that ether for anesthesia shall be—
taken from freshly opened, full containers—Bull. Pharm. 1916,
y. 30, p. 362.
Schenck, D.: The author confirms the observations of Haar with
respect to ether for anesthesia, and states further that in case the~
potassium hydroxide test of the German pharmacopeia proves to
be negative the operation should be repeated after the ether has been
evaporated to two- inane or one-half of its original volume.—Apoth.-
Zte. 1915, v. 31, p. 290-291; see also Chem. Zentralbl. 1916, y. 87,
part 2, p. 345.
Embley, E. H.: As formaldehyde may be a constituent of methyl-
ated ether, this product should not be used for anesthesia——Physiol.
Abstr. 1916, v. 1, p. 326-327. =a
Van Itallie, L., and van der Zande, J.: A note on the influence of
peroxide contained in commercial ether on the results obtained in
alkaloidal assays —Pharm. Weekblad, 1916, v. 53, p. 1.
Frankforter, G. B., and Daniels, E. A.: A report of researches
dealing with the action of aluminum chloride on ether.—Chem. News,
1916, v. 114, p. 22-23, 30-31,
Mann, Frank C.: Some bodily changes during anesthesia. ' ‘An.
experimental study.—J. Am. M. Assoc. 1916, v. 67, p. 172-175. |
137
~ Herb, Isabella C.: Ether—simplicity in its administration. The
normal anesthetie state should closely resemble natural, physiologic
sleep, and any departure therefrom may with safety be assumed to be
due to the improper selection of the anesthetic agent, to faulty tech-
nie in its administration, or to the improper preparation of the pa-
tient for anesthesia —J. Am. M. Assoc. 1916, v. 66, p. 1876-1379.
— MeCormick, A. S.: Ether when properly given will not cause
vomiting in from 70 to 80 per cent of cases, a percentage in every
way the equal of that of gas if the truth were admitted and not con-
—cealed—J. Am. M. Assoc. 1916, No. 1, p. 49.
_ Saliba, John: The antiseptic action of ether in peritoneal infec-
tions, with reports on several cases.—J. Am. M. Assoc. 1916, v. 66,
_p. 1295-1297.
Evropin, A. K. and others: Ether-oil rectal anesthesia in surgery.
_A review of several contributions on the subject—J. Am. M. Assoc.
1916, v. 67, p. 83 from Russiky Vrach, 1916, v. 15, No. 12.
JETHER ACETICUS, N. F.
_ Anon.: A reprint of the standards proposed for ethyl acetate by
_ the committee on unofficial standards—J. Am. Pharm. Assoc. 1916, v.
5, p. 86.
AGAR.
Holmes. E. M.: The monograph on agar would be more correct if
| it read: “ The dried mucilagenous substance extracted from the sev-
| eral species Gelidium (class Rhodophyceae).”—Pharm. J. 1916, v.
“97, p. 484.
Fellers, C. R.: Researches on the analysis and purification of
_ agar-agar and on some of its chemical properties—J. Ind. & Eng.
* Chem. 1916, v. 8, p. 1128-1133.
Noyes, H. A.: A description of tests for use in selecting samples
- of agar for bacteriological use.—Science, 1916, v. 44, p. 797-798.
_ Serger: A method for the recovery of agar used for bacteriological
_purposes.—Chem. Zentralbl]. 1916, v. 2, p. 671.
Loeper et al.: A preliminary study of the suitability of agar for
use as a dressing for wounds——Compt. rend. soc. biol. 1916, v. 79,
“p. 660-662.
j ; ALBUMEN.
Ostromuislenskii, I. I.: A note on the use of picramic acid as a
reagent for albuminous substances, such as egg albumen, peptone al-
_ bumose, ete—Chem. Abstr. 1916, v. 10, p. 68.
Rakuzin, M. A., et al.: A discussion of the limits of sensitivity
of certain color reactions for albumens and peptonizing enzymes.—
| Chem. Abstr. 1916, v. 10, p. 1655.
138
Maignon, F.: A report of researches to determine the effect of
seasons on the toxicity of egg albumen when fed to white rats.—
Hee Sta. Rec. 1916, v. 35, p. 61.
van der Feen, E.: Experimental data on the determination of the
molecular weight of albumen by the osmotic pressure method.—
Chem. Weekblad, 1916, v. 13, p. 410-416,
ALCOHOL.
Kressman, F. W.: Ethyl alcohol from wood, the development of ©
the process, and its requirements.—Chem. Abstr. 1916, v. 10, p. 2400
from Met. Chem. Eng. 1916, v. 15, p. 78-82.
Benson, H. K.: A description of the preparation of aleohol from
sawdust.—Pure Products, 1916, v. 12, p. 398-401.
Freeman, W. K.: A method for producing alcohol from carbon —
and hydrogen, through ethylene and ethyl sulphate. Norwegian
Patent No. 26,801, Mar. 27.—J. Am. Pharm. Assoc. 1916, v. 10, p.
1910.
Boomer, J. F.: Data showing the comparative cost of producing
alcohol in the Philippine Islands using various native plants or
plant products.—Com. Rep. 1916, No. 138, p. 988-989,
Anon.: Data showing the percentage strength of the alcohols
official in the various pharmacopceias.—Pharm. Weekblad, 1916, v.
53, p. 1621-1629.
Evans, P. M.: Data showing the boiling and condensing points
of aleohol-water mixtures.—J. Ind. & Eng. Chem. 1916, v. 8, p. 260-
262.
Anon.: Agitation of alcohol with liquid paraffin is suggested as a
means of removing mechanical impurities. An abstract.—Pharm. J.
1916, v. 96, p. 105.
Rodt, V.: Notes on the determination of very small quantities of
water in alcohol by means of the critical solution temperature. An
abstract.—J. Soc. Chem. Ind. 1916, v. 35, p. 938; see also Analyst
(The), 1916, v. 41, p. 316.
Slack, H. F.: Descriptions of methods for the detection of methyl
alcohol in ethyl aleohol.—Perf. & Ess. Oil Ree. 1916, v. 7, p. 270-271.
Kostycheff: The quantitative determination of alcohol in the pres-
ence of acetaldehyde—Chem. Abstr, 1916, v. 10, p. 2181 from Bull.
acad. sci. Petrograd, 1915, p. 327.
Ehrlich, J.: A description of a method for the determination of
ethyl alcohol in the presence of phenol.—J. Ind. & Eng. Chem. 1916,
v. 8, p. 240.
Slack, H. F.: A description of tests which should be applied to
alcohol when intended for use in the manufacture of perfumes.—_
Perf. & Ess. Oil Rec. 1916, v. 7, p. 268.
139
Lyons, A. B.: The official process for the quantitative determina-
- tion of alcohol in pharmaceutical preparations should be amended to
require that both volume measurements be made at 60° F. The
| weighing can then be made at any convenient temperature, the per-
centage being deduced from the official alcohol tables—J. Am.
- Pharm. Assoc. 1916, v. 5, p. 807-809.
- Carthans, W. F.: An article pointing out the possible errors in
' the determination of alcohol in beer.—Pure Products, 1916, v. 12,
Slack, H. F.: A deseription of methods for the quantitative deter-
| mination of alcohol in essences and similar preparations.—Perf. &
| Ess. Oil Ree. 1916, v. 7, p. 269.
| Harms, Herman: Of 53 samples of alcohol examined 5 were re-
_ jected.—Rep. Utah D. & F. Com. 1916, p. 95.
Lythgoe, Hermann C.: Of 65 samples of alcohol examined 7 were
: adulterated—Rep. Massachusetts Bd. Health, 1916, p. 450.
_ Terry, R. W.: One cf four samples of aleohol examined was below
the U.S. P. standard.—Proc. Ohio Pharm. Assoc. 1916, p. 59.
Reich, H. W.: The influence of alcohol drinking—Chem. Abstr.
- 1916, v. 10, p. 2105, from Arch. Hyg. 1916, v. 85, p. 61-116.
_ Bowers, Edwin F.: A discussion of the influence of aleohol upon
- the body and the mind.—Am. J. Clin. Med. 1916, v. 23, p. 579-583.
Editorial: New evidence against alcohol. A review of several re-
cent communications and the conclusion that these scientific findings
leave the conclusion of Quensel unimpeached. “ Work and alcohol,”
he said, “do not belong together, especially when work demands
_ wide- ee attention, exactness, and endurance.’—J. Am. M.
_ Assoc. 1916, v. 66, p. 742-743.
Editorial: Alcohol and immunity. A review of several recent con-
tributions on the subject.—J. Am. M. Assoc. 1916, v. 66, p. 962 and
1122.
McIver and Price: In a series of 147 eases of drug addiction studied
at the Philadelphia General Hospital, 108 patients said that they
had never used alcohol at all, and none of the patients were confirmed
alcoholics, although a number used alcohol to excess prior to the
- formation of the drug habit —J. Am. M. Assoc. 1916, v. 66, p. 477,
ALCOHOL, DENATURED (NONOFFICIAL).
Anon.: A list of formulas for denaturing alcohol approved by the
Commissioner of Internal Revenue at Washington, D. C.—Virginia
ePharm. 1916, v. 1, p. 70.
Billstrém, J.: In order to prevent the toxic effects resulting from
the drinking of alcohol denatured with methyl alcohol, the author
proposes that an emetic be used as the denaturant. An abstract.—
J. Am. M. Assoc. 1916, v. 66, p. 612.
140
Anon.: Comments on the official formulas for the denaturing 0
aleohol—Rocky Mountain Druggist (The), Denver, 1916, v. 30, Ne
2, p. 25-26. a
Anon.: Of 20 samples of denatured alcohol sxeaianeel none we
found to be adulterated——Rep. Massachusetts Bd. ae 1916,
p. 450. .
ALCOHOL DEHYDRATUM.
Winkler, L. W.: Commercial “absolute” alcohol usually contains
about 1 per cent of water. A method whereby this water can be re-
moved is described.—Ztschr. angew. Chem. 1916, v. 21, p. 18.
Kubierschky, Konrad: A description of a method for obtaining a
high percentage of absolute alcohol from alcohol-water mixtures
with uninterrupted operation.—Pure Products, 1916, v. 12, p. 290.
ALCOHOL, METHYL (NONOFFICIAL).
Campbell, C. L.: A process for obtaining methyl alcohol and cal-
cium acetate from the acetate liquor of wood distillation. U.S. Pat-
ent No. 1,192,987, Aug. 1—Chem. Abstr. 1916, v. 10, p. 2402.
Szarvasy, E.: A process for preparing methy] alcohol from methyl
chloride. U.S. Patent No. 1,181,697, May 2.—Chem. Abstr, 1916, v.
10, p. 1693.
Mannich and Geilmann: On the decomposition of methy] alcohol
by heated copper.—Chem. Abstr. 1916, v. 10, p. 1532 from Ber. 1916,
v. 49, p. 585-586.
Frary, Guy G.: A report showing the methyl alcohol content of -
a number of different toilet preparations.—Rep. South Dakota F. &
D. Com. 1916, p. 154-162.
Fendler, G.: Rinck’s method for the detection of methyl alcohol ©
was found to be unreliable owing to the fact that methyl alcoho] ©
yields traces of formaldehyde vad the conditions of the test.—
Zischr. Unters. Nahr.- Genussm. 1916, v. 30, p. 228-230 through
Analyst (The), 1916, v. 41, p. 316.
Mannich, C., and Geilmann, W.: A description of a method for
detecting methy] alcoho] by catalytic dehydrogenation.—Chem. Zen-
tralb]. 1916, v. 87, p. 996-997 from Archiv. Pharm. 1916, v. 254, p.
50-64,
Frankforter and Cohen: The determination of acetone in systems
of methyl alcohol, water and potassium fluoride, and equilibria in —
systems of methy] ethy] ketone, water and inorganic salts—J. Am.
Chem. Soc. 1916, v. 88, p. 1136-1141; see also Chem. Abstr. 1916,.v,.
10.43 125,
Wulling, F. J.: A paper dealing with the danger incurred in,the
use of wood alcohol by those ignorant of its properties. A number.
of cases of poisoning is cited —Drug. Cire. 1916, v. 60, p. 206. |
141
~ Anon.: There is no reason to believe that methyl alcohol as a fuel
possesses any special dangers or disadvantages. The products of its
complete combustion are the same as those of the combustion of
ethy! alcohol, namely, water and carbon dioxide. Two cases of
poisoning attributed to wood alcohol used as a fuel are on record.
_ These cases are probably due to the effects of incomplete combus-
tion.—J. Am. M. Assoc. 1916, v. 66, p. 913.
ALETRIS, N. F.
Lilly, J. K.: One lot of Chamelirium luteum, false unicorn, was
offered for Aletris farinosa—oOil, Paint & Drug. Rep. 1916, v. 90,
No. 16, p. 46.
ALOE.
Stacy, C. E.: A description of a new color reaction for aloes. A
_ pink color develops when a potassium ferricyanide solution is added
| to an aqueous extract of Barbadoes aloes. Socotrine aloes, Cape
| aloes, and commercial aloin give a green color—Analyst, 1916, v.
i Eaonilte: W. L.: One sample of aloes examined contained no
aloin.—J. Am. Pharm. Assoc. 1916, v. 5, p. 536,
ALOINUM.
_ Seel, E., and Kelber, C.: Data showing the molecular weight of
_aloin and its oxidation products as revealed by determinations made
- according to different methods.—Ber. deutsch. chem. Gesellsch.
1916, v. 49, p. 2364-2368.
Léger, I. E.: A report of researches on barbaloin, iso- and é-bar-
_ baloin. Experiments throwing light on the structure of these com-
/ pounds are described in ‘detail.—Ann. chim. applicata, 1916, v. 6,
| p. 318-381.
| Léger, E.: An account of researches on the preparation of iso-
- meric acetyl derivatives of nataloin and homonataloin.—J. pharm.
et chim. 1916, v. 13, p. 813-317; see also Compt. rend. acad. se. 1916,
_ v. 162, p. 506-508.
ALTHAA.
Rusby, H. H.: Cut althea, thinly coated with milk of lime, as
_ Jamaica ginger and German calamus are treated, is of frequent ap-
pearance. It is now recognized that other drugs are adulterated
_ when so treated, and it would seem that the same view should be
_ taken of this drug —J. Am. Pharm. Assoc. 1916, v. 5, p. 536.
Gutbier, A., and Weise, G. L.: An article dealing with the prepa-
ration and general properties of the colloidal solutions obtained by
- extracting the roots of marsh mallow.—Kolloid. Ztschr, 1916, v. 19,
p. 177-191.
142
ALUMEN EXSICCATUM.
Vanderkleed, C. E.: Great improvement in the moisture conten
of burnt alum has been noted, none of the samples examined con-
taining more than 6 per cent, which is very close to our arbitrary
standard of 5 per cent moisture.—J. Am. Pharm. Assoc. 1916, v.
5, p. 536.
ALUMINI HYDROXIDUM.
Rakuzin, M. A.: A report of investigations dealing with the ad-
sorption of albuminous substances by aluminum hydroxide. An ab-
stract.—Pharm. J. 1916, v. 97, p. 595.
AMMONII BROMIDUM.
Beringer, George M.: The purity of bromide of ammonium has
been increased from 97 per cent absolute bromide in the Eighth Re-
vision to 98.5 per cent in the Ninth Revision—Am, Druggist, 1916,
v. 64, No. 8, p. 23.
Smith, Alexander, and Eastback, Herbert E.: A study of the
allotropy, and solubility of ammonium bromide in water.—J. Am.
Chem. Soc. 1916, v. 38, p. 1261-1266. .
AMMONII CARBONAS.
Bueb and Deutsche Continental Gas-Ges: A process for making —
solid ammonium carbonate. German Patent No. 285.531, Mar. 22.—
Chem. Abstr. 1916 v. 10, p. 669.
Wiebelitz: The author reports that a salt which is a true am- ©
monium carbonate is now on the market. This new salt contains 21 —
per cent of NH, and 55.7 per cent of CO, and corresponds to the —
formula NH,HCO,. An abstract.—Pharm. Weekblad, 1916, v. 53,
p. 1450.
E’we, G. E.: Two lots of ammonium carbonate examined wero
low in NH, content, containing 29.15 per cent and 30.85 per cent,
respectively—Proc. Pennsylvania Pharm. Assoc. 1916,
AMMONIT CHLORIDUM.
Coleman, Warren: From experiments, it is concluded that am-
meonium chloride facilitates expectoration and can be considered an
expectorant within the definition of the term.—Am. J. Med. 1916,
v. 152, p. 569-574.
AMMONII IODIDUM.
Smith, Alexander, and Eastlack, Herbert E.: Data showing the
solubilities of ammonium iodide between —19° and 136° C., and the.
absence of a transition point.—J. Am. Chem. Soc. 1916, v. 88,
p. 1500-1502.
143
AMYGDALA DULCIS.
Holmes, E. M.: The U.S. P. reverts to a trinomial nomenclature
or sweet almond thus, Prunus Amygdalus dulcis, as tf uncertain
whether the plant should be regarded as a form or a variety.—
Pharm. J. 1916, v. 97, p. 484.
AMYLUM.
_ Harrison, W.: A consideration of some properties of starch from
a colloid-chemical point of view.—Physiol. Abstr. 1916, v. 1, p. 76.
Huizinga, Alida: Experimental data on the determination of
“starch by the methods of Baumert and Bode—Chem. Weekblad,
2916, v. 13, p. 198-205.
| Clementi, A.: A discussion of certain factors which exert a dis-
turbing influence on the color reaction between starch and iodine.
An abstract—C. U. C. P. Alumni J. 1916, v. 23, p. 234.
_ Northrop and Nelson: A report of an investigation showing that
or acid is au pacuias constituent of starch—J. Am. Chem.
ANETHOL, N. F.
_ Anon.: Notes on the solidifying and melting point of anethol—
‘Perf. & Ess. Oil Rec. 1916, v. 7, p. 46.
. Anon.: A be of Seance anethol was found to have a melting
point of 22 to 22.5° C. and a congealing point of about 21° C. Its
specific gravity at 25° C. was 0.986.—Pref. & Ess. Oil Ree. 1916,
Dy. 7, p. 82.
ANGELICA: RADIX, N. F.
Lilly, J. K.: One lot of angelica root examined contained a high
"percentage of calamus.—Oil, Paint & Drug Rep. 1916, v. 90, No. 16,
ANISUM.
Sayre, L. E.: A sample of anise examined was below standard. It
contained insects and numerous small black seeds and an excess of
stems. —Bull. Kansas Bd. Health, 1916, p. 10.
ANTIMONIT ET POTASSH TARTRAS.
Anon.: Tartar emetic and sodium bicarbonate mixed in aqueous
solution precipitate on standing. The sediment formed is probably
crnony hydroxide.—Rep. Chem. Lab. Am. M. Assoc, 1916, v. 9,
part 2, p. 18-19.
144
Rogers, Sir Leonard, and Hume. N. H.: A report on the treat:
ment of kala-azar by intravenous injections of tartar emetic and by
inunctions of metallic antimony.—Brit. M. J. 1916, v. 1, p. 301-803
Castellani, Aldo: Tartar emetic is stated to be efficacious in the
treatment of various protazoal diseases. Its efficacy in the treat-
ment of trypanosomiasis has been proven and it may be considered
a specific in kala-azar, and oriental sore. It is also useful in the
treatment of yaws.—Brit. M. J. 1916, v. 2, p. 552.
ANTIMONIUM SULPHURATUM, N. F.
Hutin, A.: A description of a rapid method for the testing of
commercial sulphide of antimony.—Ann. chim. ocala 1916, v. 2%
p. 3-7.
E’we. G. E.: One lot labeled “Antimony, black sulphuretted ” was
a: mixture of powdered marble and Jampblack. —Proc. Pennsylvania
Pharm. Assoc. 1916.
ANTIPYRINA.
Francois, Maurice: From experiments, it is concluded that titra-
tion with an alcoholic solution of iodine in the presence of mercuric —
chloride is more accarate than the method for the determination of
antipyrine given in the Ph. Fr—aAnn. Falsif. 1916, v. 9, p. 459-464.”
Finnemore, H., and Colverd, J.: A note on the incompatibility of —
antipyrine with sodium salicylate and magnesium sulphate. An ab-
stract.—C. U. C. P. Alumni J. 1916, v. 23, p. 187.
APII FRUCTUS, N. F.
Alsberg, C. L.: The tentative standards laid down by the Bureau
of Chemistry require that the material shall yield not less than 95.0
per cent of sound seed, not less than 2.0 per cent of volatile oil, and
not more than 10 per cent of ash—S. R. A.—Chem. 1916, No. 16,
p. 30.
APOCYNUM, N. F-.
Trier, G.: A discussion of the properties of cymarine from Cana-
dian hemp and its relation to the heart poisons.—J. pharm. et chim.
1916, v. 13, p. 105-110.
APOMORPHINZ HYDROCHLORIDUM.
Anon.: When dispensing apomorphine hydrochloride in solution,
all trace of alkali should be removed from the bottle. The faiatest
trace of alkali causes the solution to turn green—Bull. Pharm. 1916,
v. 30, p. 214.
145
Francis, J. M.: Apomorphine is very unstable and inevitably
udergoes decomposition whether dispensed in the form of an ordi-
ry powder or in tablets.—Am. Food J, 1916, v. 11, p. 409.
De La Paz, Daniel, and Garcia, Faustino: An experimental study
m the use of apomorphine to remove foreign bodies from the re-
ratory passages.—Philippine J. Sc. 1916, v. 11, see. b, p. 51-59.
AQUA.
G. J. v. M.: A review of a volume by J. Tillmans on the chemical
Xamination of potable waters and those employed in manufactur-
ig processes.—Chem. Weekblad, 1916, v. 13, p. 1028.
Tillmans, J., and Mildner,-H.: Directions for the testing of water
ntended for use in the preparation of salvarsan.—Chem. Abstr.
916, v. 10, p. 1402 from Ztschr. angew. Chem, 1915, v. 28, p. 469-474.
Goester, L. E.: Notes on the analysis of potable waters——Pharm.
Weekblad, 1916, v. 53, p. 1345-1360.
_ Trillat, M.: A note on the use of red wine by the Romans for
letermining the alkalinity of water—Chem. & Drug. 1916, v. 88, p.
"On.
~ Dhommée, René: A comparative study of the methods for dc-
ermining the alkalinity of water.—Bull. sc., pharmacol. 1916, v. 23,
». 92-97. ,
' Wagenaar, M.: A description of a short method for the deter-
mination of alkalies in potable water, accompanied by data ob-
fained in a number of analyses.—Pharm. Weekblad, 1916, v. 53, p.
232-238.
' Kay, S. A., and Newlands, Susan H.: A report of experiments
on the determination of the hardness of natural waters.—J. Soe.
hem. Ind. 1916, v. 35, p. 445-447,
_ Norton and Knowles: A study of the indicators suitable for the
determination of temporary hardness in water.—J. Am. Chem. Soc.
1916, v. 38, p. 877-884; see also Chem. Abstr. 1916, v. 10, p. 1565.
_ Kolthoff, I. M.: Notes on the quantitative determination of sma!]
quantities of metals in potable water.—Pharm. Weekblad, 1916, v.
3, p. 1739-1749.
Le Roy, G.-A.: The determination of free chlorine in water sup-
plies—Compt. rend. acad. sc. 1916, v. 162, p. 827-829; see also Chem.
Abstr. 1916, v. 10, p. 1564.
Kolthoff, I. M.: Data showing the influence of neutral salts on the
jonization constant of water—Chem. Weekblad, 1916, v. 13, p. 1150.—
oe
| ’ Carles, P.: A note on the presence of ammonium salts in artesian
water.— Répert. pharm. 1916, v. 28, part 1, p. 60-66,
110095°—19——10
146
Race, Joseph: Experimental data on the making of bacterial
counts in the examination of water—Am. J. Public Health, 1916,
v. 6, p. 488-496. a
Schweiz: A description of a method for the detection of bacillus
coli in water—Yearbook of Pharmacy, 1916, p. 77, from Apoth.-Ztg,
1916, v. 54, p. 194. 7
Smith, Alden E.: Water as a therapeutic agent.—J. Am. Inst
Homeopathy, 1916, v. 8, p. 1159-1162; see also Chem. Abstr. 1916,
v. 10, p. 1554.
Colin, H.: A study of the sterilization of water by means of car-
ben dioxide under pressure. An abstract——Apoth.-Ztg. 1916, v. 31,
p. 652.
Golse, J.: A description of a method for controlling the degree of
purification of water by javellization after the active chlorine has
been eliminated with sodium hyposulphite——J. pharm. et chim. 1916,
v. 14, p. 8-13.
Comte: A description of some proposed improvements in the —
method of javellization of drinking water.—J. pharm. et chim. 1916, |
v. 14, p. 261-263.
Anon.: A description of a field water purification plant.—Chem, -
Abstr. 1916, v. 10, p. 1063 from Can. Engr. 1916, v. 10 p. 189-190.
AQUAS.
Thum, John K.: A description of a method for making medi-
cated waters. The method consists principally in dissolving the oil
in distilled water by agitation without the addition of the usual
agents employed for the purpose of assisting in the subdivision of
the oil— J. Am. Pharm. Assoc. 1916, v. 5, p. 736-737.
Guyote, René: Experimental data showing the effect of oxygen”
and oxidizing agents, reducing agents, light, electricity, antiseptics, —
certain metals, etc., upon the coler of distilled aromatic waters with
special reference to orange flower water.—J. pharm. et chim. 1916,
v. 13, p. 37-46. ;
Pinilla, H. Rodriguez: A short article enumerating and describ-
ing the purgative mineral waters of Spain.—Farm. Espan. 1916, v.
48, p. 599-601.
AQUA AMMONIA.
Foxwell, G. E.: A description of a colorimetric method for the
estimation of ammonia. The method is based on the color produced —
by an excess of phenol and a little sodium hypochlorite——Chem. —
Eng. 1916, v. 23, p. 182.
Woelk: A description of a method for the detection of pyridine
in ammonia water. The method is based en the production of an
147
jpyreumatic odor when an ammonium salt containing pyridine is
turated with borax. An abstract.—Drug. Circ. 1916, v. 60, p. 146.
Ipert, S.: A description of the picrate method for the deter-
nation of naphthalene in ammonia water. An abstract.—Pharm.
p1916, v. 96, p. 525.
ngfeldt, N. O.: Methods for the detection of tarry substances
1 ammonia.—Svensk. farm. Tidskr. 1916, v. 20, p. 237
AQUA AMMONIZ FORTIOR.
Scoville, Wilbur L.: It is fortunate that the pharmacist seldom
or never has a call for stronger ammonia water for medicinal use
as agitation or a very moderate degree of heat soon reduces the
th to 25 per cent or less-—Bull. Pharm. 1916, v. 30, p. 362.
AQUA AURANTII FLORUM.
tr Guyot, René: Notes on = color changes which take piseie in dis-
AQUA CHLOROFORMI.
i Anon.: A suggested recipe for the preparation of a mentholated
chloroform water.—C. U. C. P. Alumni J. 1916, v. 23, p. 12.
AQUA CREOSOTI.
_ Diekman, George C.: The reason for retaining creosote water
in the U.S. P. is not apparent. The quantity of creosote which it
contains is so small that it is of no value medicinally and its use
as a vehicle will hardly be justified or recommended.—Pract. Drug.
916, v. 34, No. 10, p. 25.
AQUA DESTILLATA.
4 BT ilimans, Mildner: On the testing of distilled water intended to
be utilized for the preparation of solutions of salvarsan. A review
‘oi the reagents and tests to be applied—Siidd. Apoth.-Ztg. 1916, v.
56, p. 2-3.
_ E’we, G. E.: One lot of distilled water examined yielded 0.0956 gm.
residue upon evaporation of 100 cc., while the U. S. P. limit is
0.05 gm. It was otherwise U. S. P.—Proc. Pennsylvania Pharm.
. 1916, p. 118.
i AQUA HAMAMELIDIS.
3
_ Lythgoe, Hermann C.: Of nine samples of hamamelis water ex-
1, one was adulterated—Rep. Massachusetts Bd. Health, 1916,
¥
148
Tice, William G.: Of 31 samples of hamamelis water examinec
8 were below standard.—Rep. New Jersey Dept. Health, 1916, p. i
Hostmann, Jeannot: Two of the 10 samples of extract of witch
hazel examined were low in alcohol content—Proc. New Jers
Pharm. Assoc. 1916, p. 77. ‘7:
ARALIA, N. F. 3
Anon.: Information relative to the cultivation and harvesting of
spikenard is given.—N. A. R. D. J. 1916, v. 22, p. 1024.
ARGENTI NITRAS. 2
Bridgman, P. W.: An imvestigation of the polymorphic changes
taking place in the univalent nitrates under pressure——Chem. Abstr.
1916, v. 10, p. 1955, from Proc. Am. Acad. Arts Sci. 1916, v. 51}a@
581- 625.
Ramond: A report on the use of silver nitrate as a local applica-
tion for the treatment of Vincent’s angina.— Yearbook of Pharmacy,
1916, p. 247, from Progrés Méd 1916, v. 32, p. 35. — 4
ARGENTI NITRAS FUSUS.
Anon.: A new form of fused silver nitrate is being introduced im
Germany. Jt consists of glass rods on which a small amount of
silver nitrate has been fused. It is said that these caustic rods are
an improvement over the formerly used glass rods which were)
merely dipped into a strong solution of silver nitrate.-—Siidd. Apoth.-
Ztg. 1916, v. 56, p. 72. |
ARGENTUM (NONOFFICIAL COMPOUNDS).
Wastenson, Hugo: Data obtained in the analysis of protein com-
pounds of silver—Svensk farm. Tidskr. 1916, v. 20, p. 57-62; ser
also Pharm. Post, 1916, v. 49, p. 187-188; Chem. Abstr. 1916, v. 10)
p. 1773-1774. Lin
Vanderkleed, C. E., and E’we, G. E.: A description of a method
for the determination of taints in colloidal silver ee
tions.—J. Am. Pharm. Assoc. 1916, v. 5, p. 715-716.
Anon.: Comments on the methods for the asay of collargol and
protargol as given in the supplement to the Ph. Ndl. 1V.—Schweiz.
Apoth.-Ztg, 1916, v. 54, p. 340.
Robinson, W. J.: A note on the incompatability of argyrol with
jodine. An abstract ——Drug. Cire. 1916, v. 60, p. 337.
Edwards, E, Gard.: Stains of nated on the hands or clothing
can be readily removed by rubbing with a salted grease, such a
bacon grease, followed by soap and water.—J. Am. M. Assoc. 1916
v. 66, p. 592. i
149
ARSENI TRIOXIDUM.
Editorial: The toxicity of arsenous and arsenic acids. The rela-
vely greater toxicity of arsenous in comparison with arsenic acid
; in the proportion of 10:6 in the case of the lethal dose required
fo intravenous injection in animals. Perfusion experiments with
the isolated frog’s heart indicate that the arsenous compounds are
00 times as harmful as those of arsenic acid.—J. Am. M. Assoc.
916, v. 66, p. 579-580.
_Joachimoglu, G.: An experimental study of the dev Slonineee of
blerance for arsenic.—Pharm. Post, 1916, v. 49, p. 107-108, 119-121;
ec also Arch. exper. Path. u. Pra meot 1916, v. 79, p. 419-442;
Shem. Abstr. 1916, v. 10, p. 1680.
_Anon.: An editorial frye hays the mechanism by which the or-
panism acquires tolerance for arsenic.—J. Am. M. Assoc. 1916, v. 67,
9. 621-622.
ARSENIC (NONOFFICIAL COMPOUNDS).
_Karrer, P.: A paper giving the origin, history, and therapeutic
uses of organic arsenic compounds, and discussing the merits of cer-
tain methods for the preparation of these compounds.—Chem. Zen-
ralbl. 1916, v. 1, p. 1088,
- Moore, Benjamin: The history of organic compounds of arsenic
in the treatment of protozoan diseases.—Brit. M. J. 1916, v. 1, p.
_ Kahn, Joseph: The organic compounds of arsenic. A general re-
‘yiew of their chemical constitution—Proc. New York Pharm. Assoc.
1916, p. 142-152.
_ de M. Abad, Mariano: On the derivatives of arsenobenzol. A
ge Hspan. 1916, v. 48, p. 97-99, 113-117,
| Burroughs Wellcome & Co.: A note on the arsenic content of sal-
/yarsan and neosalvarsan. Also on kharsivan and neokharsivan.—
Brit. M. J. 1916, v. 2, p. 201-202.
Engelhardt and Winters: A method for the estimation of
| atoxyl.—Chem. Abstr. 1916, v. 10, p. 804 from J. Am. Pharm. Assoc.
1915, v. 4, p. 1468-1471.
| Danysz, J.: A report on the bad effects observed after the injec-
‘tion of products of the arsenobenzol group, and on the anaphylactic
trises.—Compt. rend. acad. sc. 1916, v. 168, p. 246-248.
~ Danysz, J.: A discussion of the causes of intolerance to the arseno-
/benzenes and the methods for avoiding or preventing it—Compt.
rend. acad. sc. 1916, v. 163, p. 535-538,
~ Danysz: The compound “ arsenol-bromo-argentique” is designated
| as No. 88. The compound “ sulphate of dioxy-diamino-arseno-benzo-
150
late of silver bromide and antimony! ” is designated as No. 102. Bott
of these compounds are said to be useful in the treatment of trypane
somiases.—Répert. Pharm. 1916, v. 28, part 1, p. 16-17, from Compt
rend. acad. sc. Aug. 24, 1914. :
Bonard, N. S.: A discussion of the chemistry, posology, and ad
ministration of luargol—a new remedy for syphilis.—Lancet, 1916
v. 191, p. 554-558.
Anon.: Dalimer and Levy-Franckel report that they have obtained
favorable results in the treatment of syphilis by the injection oi
Danysz’s arseno-antimony-silver compound, “102,” or “ Luargol.
No attempt was made to study the effect of this substance on the
course of the disease, the investigation having been limited to th
curing of the lesions—Pharm. J. 1916, v. 96, p. 423, from Compt,
rend. acad. sc. 1916, v. 162, p. 440.
Anon.: Danysz, of the Pasteur Institute, two years ago directed
attention to the value of two compounds of arsenobenzol, one in com-
bination in silver bromide, the other, which he called “102,” an
arsenobenzol-silver bromide-antimonyl compound. The results ob-
tained in the treatment of 550 cases of syphilis were mest satis.
factory. In 80 per cent of the cases treated the injection of 100 t
120 centigrams of “102” resulted in a negative blood test two months
after treatment.—Pharm. J. 1916, v. 96, p. 77, from Compt. rend.
acad. se. 1915, v. 161, p. 685. .
Renault, Fournier, and Guénot: Notes on the treatment of syphilis”
with “arsenobenzol bromo-argentique antimonié.”—Répert. Pharm.
1916, v. 28, part 1, p. 17-18, from Compt. rend. acad. sc. Nov. 29, 19155
Dudley, Sheldon I*.: An accouns of an experience with galyl at the
Royal Naval Hospital, Chatham.—Lancet, 1916, v. 191, p. 59-60,
Anon.: Venarsen and other preparations of the Intravenous Prod
ucts Co. Vernarsen was found to be a simple solution containing,
sodium cacodylate with mercuric iodide and sodium iodide.—J. Am.
M. Assoc. 1916, v. 66, p. 978.
Trimble, William B., and Rothwell, John J.: A comparative study
of salvarsan and neosalvarsan in the treatment of syphilis ——J. Am.
M. Assoc. 1916, v. $7, p. 1984-1987. .
Ormsby, O. S., and Mitchell, J. H.: The new supply of salvarsan
and neosalvarsan is stated to be distinctly more toxic than that for
merly obtained from Germany. A striking increase in the number
of severe reactions following injections of these preparations has
been observed.—J. Am. M. Assoc. 1916, v. 67, p. 1756.
Pearce, Louise, and Brown, Wade H.: Chemopathological studies
with compounds of arsenic. IV. Investigations to determine the
character and distribution of renal injury produced by arsenicals a
indicated by the process of repair.—J. Exper. M. 1916, v. 23, p. 448
459,
151
| Neosalvarsan—Moody, A. M.: A report of undesirable symptoms
following the injection of neosalvarsan.—J. Am. M. Assoc. 1916, ¥
67, p. 1757.
Beine, René: A report of a case of exfoliative dermatitis follow-
ing neosalvarsan injections.—Boston M. & S. J. 1916, v. 175, p. 96-99.
_ Salvarsan—Schamberg, Jay F., et al.: A report on the therapeu-
tic effect of the administration of arsenobenzol by mouth. Experi-
‘ments showed that administration by mouth is capable of producing
‘a curative influence on the lesions of syphilis, but the authors do not
‘advise its use in this manner, inasmuch as there are more efficient
favenues of administration—J. Am. M. Assoc. 1916, v. 67, p.
} 1919-1923.
| Frayton, Frank A.: A description of a simplified procedure for
he administration of salvarsan, including illustrations of the ap-
paratus employed.—J. Am. M. Assoc. 1916, v. 66, p. 1921-1922.
_ Engwer: From experiments, it is concluded that the rate of excre-
Bion of salvarsan in the urine is no indication of the value of the
_ Sieburg, E.: A study of the decomposition products of salvarsan
as they appear in the urine.—Physiol. Abstr. 1916, v. 1, p. 495 from
Bischr. physiol. Chem. 1916, v. 97, p. 538-108.
~ Willcox, W. H., and Webster, J.: Researches on the toxicity of
‘salvarsan. A number of chemical tests for the identification of the
latter are given.—Brit. M. J. 1916, v. 1, p. 473-478; see also Analyst
(The), 1916, v. 41, p. 231-240.
- Puckner, W. A.: A copy of the report of the council of pharmacy
* chemistry of the American Medical Association on arsenobenzol
(Dermatological Research 2 yak Philadelphia Polyclinic)
and diarsenol (Synthetic M. Assoc. 1916, v. 67,
D mo9.
_ Anon.: Fictitious neosalvarsan was found on examination to con-
‘sist of ordinary table salt colored yellow with naphthol yellow S.—
D.-A. Apoth.-Ztg. 1916, v. 36, p. 172.
_ Anon.: Notes on deaths following the administration of salvar-
‘san.—Deutsch. med. Wcehnschr. 1916, v. 42, p. 106-107.
* Ellis, John D.: The author reports that toxic symptoms were ne-
ticed in the great majority of cases in which salvarsan, purchased
during the last three months, was administered.—J. Am. M. Assoe.
1916, v. 67, p. 1757.
y Anon.: Under the caption “ London letter,” it is stated that the
‘Many fatalities following the administration of salvarsan indicate
that the latter is not a ate drug. Furthermore, that the same ap-
pe to its substitutes.—J. Am. M. Assoc. 1916, y. 67, p. 1030.
152 “ ”
Lewitt, M.: A confirmation and elaboration of the statement c
Stern concerning the excretion of salvarsan after intravenous inje.
tion of concentrated solution.—Chem. Zentralbl. 1916, v. 11, p. 11%
Bland-Sutton, Sir John: A report of a case of jccoue cancer.
Brit. M. J. 1916, v. 2, p. 788-789. -
Levison, Louis A.: In a discussion of the results of the treatmen
of arterial hypertension due to or associated with syphilis, it is states
that the careful use of mercury or salvarsan has not produced bac
effects on kidneys damaged by arterial disease—J. Am. M. Asso¢ .
1916, v. 67, p. 730-733. 4
ener Nathaniel Bowditch: A clinical study of the effect of s sal
varsan in the treatment of double infections, tuberculosis am
syphilis—Am. J. M. Se. 1916, v. 152, p. 823-845. .
King, John T.: A report of cases showing the quantitative effec
of salvarsan on the Wassermann reaction of the blood—J. Am. M
Assoc. 1916, v. 67, p. 1669-1671.
Douglas, S. RB. ., and Colebrook, L.: Experimental obser mation 01
the bactericidal power acquired by the serum after the administra
tion of salvarsan or neosalvarsan.—Lancet, 1916, v. 190, p. 181-183.
Ormsby and Mitchell: In its uniform and nontoxic action, arseno
benzol commends itself as a remedial agent of great value in the
treatment of syphilis, and its successful preparation marks an
achievement in American chemotherapy. While a sufficient experi
ence has not as yet been had from which to draw ultimate conclue
sions, we believe its therapeutic accomplishments, together with it
safety of administration, recommend its continued employment.—
J. Am. M. Assoc. 1916, v. 66, p. 867-868.
Wile, U. J.: A report on the efficiency and nontoxicity of arseno
benzol. An analyses of 243 cases of syphilis treated at the Universit
Hospital, Ann Arbor, is included—J. Am. M. Assoc. 1916, v. 66
p. 1880.
Anon: “ Diarsenol,” a substitute for salvarsan, is being manufac
tured in Canada under the patronage of the University of Toronto.—
J. Am. M. Assoc. 1916, v. 66, p. 590. ’
Gardner, James A.: In a discussion of the comparative values @}
salvarsan and diarsenol, it is stated that the same care, in preparatiol
and technic, in intravenous injections, should be observed with th
latter J. Am. M. Assoc. 1916, v. 66, p. 13038
1304.
Cook, Abner H.: In a report on a case in which alarming symp
toms followed the administration of diarsenol, the following al
offered as possible causes: The presence of a chemical poison acting
lirect or through the suprarenals on the vasomotor center, or surgical
yy anaphy lactic shock.—J. Am. M. Assoc. 1916, v. 66, p. 865-866.
Likes, Sylvan H., and Schoenrich, Herbert: A report of a case of
“syncope iminediately after the administration of diarsenol.—New
| York M. J. 1916, v. 104, p. 64-66.
Lucey, H. C.: A discussion of the therapeutics and reaction effects
of kharsivan—Brit. M. J. 1916, v. 1, p. 614-617.
_ For additional references on organic compounds of arsenic sev
Index Med.; Physiol. Abstr.; Brit. M. J.; J. A. M. A.; and Chem.
‘Abstr.
ASAFCTIDA.
Schneider, Albert: It is impossible to obtain the pharmacopcial
‘ash standard (30 per cent) for asafetida without adulterating the
drug heavily with sand, clay, diatomaceous earth, dirt, or perhaps a
very high percentage of vegetable matter rich in silica, as gramineous
- chaff—Drug. Cire. 1916, v. 60, p. 693.
Rusby, H. H.: It is unfortunate that advantage has not been taken
of the methods worked out in the New York Laboratory of the De-
partment of Agriculture for the identification of the resin of asa-
fetida. At the time that these methods were proposed their accuracy
was challenged by certain British authorities, but their objections
~ have been completely discredited since——Drug. Cire. 1916, v. 60,
p. 538.
_ Howard, Charles D.: A sample of asafedita examined contained
approximately 65 per cent of mineral matter; its solubility in alcohol
was but 33.65 per cent—Bull. New Hampshire Bd. Health, 1916, v. 4,
Nos. 7-8, p. 129.
_ VWanderkleed, C. E.: Two samples of asafetida examined yielded
61.9 and 59 per cent, respectively, of alcohol-soluble pee 13.1 and
22.5 per cent of : J. Am. Pharm. Assoc. 1916, v. 5, p. 53
Scoville, W. L.: Six lots of asafetida Sed ranged ae 36 per
' cent soluble in alcohol to 77.3 per cent. The ash content ranged
_ from 2.06 to 40 per cent.—J. Am. Pharm. Assoe. 1916, v. 5, p. 536.
_ Patch, E. L.: Of four samples of asafetida examined, the alcohol-
soluble material therein varied from 51 to 65 per cent, the ash con-
tent from 11 to 18 per cent.—J. Am. Pharm. Assoc. 1916, v. 5, p. 036.
Roberts, J. G.: Of the six samples of asafetida examined, only two
_ were of U. S. P. quality. The others contained insufficient amounts
of alcohol-soluble matter and yielded an excess of ash.—Proe. Pennsyl-
vania Pharm. Assoc. 1916, p. 109.
Swift, E. G.: Eleven lots of asafetida examined ranged from 32.76
per cent to 76.4 soluble in alcohol. Eight samples contained more
.
154
than 64 per cent of material soluble in alcohol, and, with one ex-
ception, less than 8 per cent of ash. The lowest ash content was
4.58 per cent.—Oil, Paint & Drug Rep. 1916, v. 90, No. 16, p. 46.
ASCLEPIAS, N. F.
Anon.: Information relative to the cultivation and harvesting of —
pleurisy root is given.—N. A. R. D. J. 1916, v. 22, p. 1178-1174.
Hart, Fannie: A comparison of the histological characters of —
Asclepias tuberosa and two of its substitutes, Asclepias decumbens
and Asclepias syriaca—Proe. New York Pharm. Assoc. 1916, p. _
274-278; see also Pract. Drug. 1916, v. 34, No. 8, p. 30-31.
ASPIDIUM.
Lilly, J. K.: Five lots of aspidium examined consisted of fern
rhizomes of other species; two lots were old and unsatisfactory. It
was difficult to procure good aspidium throughout the year.—Oil,
Paint & Drug Rep. 1916, v. 90, No. 16, p. 46.
ASPIDOSPERMA.
Holmes, E. M.: Quebracho blanco is used as a specific name, with-
out a hyphen thus: Aspidosperma quebracho blanco Schlectendabl,
suggesting when compared with Prunus Amygdalus dulcis, that
blanco is the name of a form or variety of Aspidosperma Quebracho.—
Pharm. J. 1916, v. 97, p. 484.
Anon.: Aspidosperma was in the 1890 U. 8. P. and its reintro-
duction is surprising in view of its limited use——Drug Topics, 1916,
ING= 9.3/6.
Vanderkleed, C. E.: The allkaloidal content of the two samples of
quebracho examined was 0.95 and 1.22 per cent, respectively.—J. Am.
Pharm. Assoc. 1916, v. 5, p. 543.
Anon.: The alkaloidal content of one sample of quebracho assayed
was above standard.—Proc. Pennsylvania Pharm. Assoc. 1916, p. 119.
ATROPINA.
Anon.: A note on the preparation of atropine from Datura alba
collected in the Philippines.—Pharm. J. 1916, v. 97, p. 297.
Eder, R.: Descriptions of reactions for the identification of atro-
pine and the closely related mydriatic alkaloids.—Schweiz. Apoth.-
Ztg. 1916, v. 54, p. 501-504, 517-520, 534-537, 544-548, 560-563,
09-612, 621-624, 657-661, 669-670, 685-687, 717-719.
Zellweger, R.: From experiments, it is concluded that the odor test
of the Ph. Helv. IX for atropine fails with a 3 per cent aqueous solu-
tion of chromic acid, but gives results if the atropine is mixed in a
155
ry test tube with chromium oxide and heated in a small flame until
Jensen, H. R.: On account of the shortage of atropine, it is sug-
gested that levo-hyoscyamine be used in its stead, as the latter has a
| nism between atropine and certain central emetics.—J. Pharmacol. &
Exper. Therap. 1916, v. 9, p. 11-25.
_ Sutpehn, T. Y.: A report of an unusual complication in a case of
| glaucoma due to atropine-——New York M. J. 1916, v. 103, p. 1075.
McGuigan, Hugh: A study of the influence of atropine and pilo-
- carpine on the glycogenic function.—J. Pharmacol. & Exper. Therap.
1916, v. 8, p. 407-415.
| Marris, H. F.: On the use of atropine as an aid to the diagnosis
_ of typhoid and paratyphoid A and B infections.—Brit. M. J. 1916,
mv. 2, p. (17-720.
_ Zunz and Tysebaert: A study of the action of atropine sulphate
an
-
be
y. 8, p. 325-337; see also J. Am. M. Assoc, 1916, v. 67, p. 152; Chem.
| Abstr. 1916, v. 10, p. 2003.
AURANTIT AMARI CORTEX.
_ Holmes, KE. M.: The name chosen for the bitter orange in the Ph.
_ Brit. appears to be preferable, viz, Citrus Aurantium, var. Bigaradia,
AURi ET SODIT CHLORIDUM.
_ Vanino, L., and Hartwagner, F.: A discussion of an iodometric
_ determination of gold, with a description of a new method evolved
by the author.—Ztschr. anal. Chem. 1916, v. 55, p. 377-388.
BALSAMUM PERUVIANUM.
_ Holmes, E. M.: The choice of the botanical name TJoluifera
b3 Peretre seems incongruous, since the generic name Z'oluifera means
. tolu bearer, which obviously this plant is not. The Ph. Brit. name,
_ Myroxylon Pereira, is evidently more appropriate.—Pharm. J. 1916,
vv. 97, p. 484.
i Umney, J. C.: The limits of specific gravity for balsam Peru,
€ 1.130 to 1.160 at 25° C., are too liberal. Samples of the true balsam
- fall within the specific gravity limits of 1.135 to 1.155 at 25° C.—
_ Perf. & Ess. Oil Rec. 1916, v. 7, p. 345.
Umney, J. C.: Although the Ph. Brit. limits of specific gravity
1.140 to 1.158 include nearly all pure samples of Peru balsam, an
7
:
>
;
4
156
occasional sample may be found as low as 1.185.—Perf. & Ess. Oil
Rec. 1916, v. 7, p. 249. a,
Patch, BE, L.: In answer to a criticism of a lot of balsam of Peru
examined, a leading importer stated that although he handled about
60 per cent of the country’s total importation, and tested every parcel
that he received, he very rarely, in fact practically never, found any
balsam that was strictly U. S. P—J. Am. Pharm. Assoc. 1916, v. 5,
p. 536, 4
Schimmel & Co.: Adulteration of a sample of balsam of Peru that
answered the requirements of the Ph. Germ. was detected by its
solubility in dilute alcohol. The pure balsam forms a clear solution,
only, with equal parts of 90 per cent alcohol—D.-A. Apoth.-Ztg.
1916, v. 37, p. 129
E’we, G. E.: One lot of balsam of Peru examined contained exces-
sive acid resins.—Proc. Pennsylvania Pharm. Assoc. 1916, p. 116.
BALSAMUM TOLUTANUM.
Holmes, E. M.: The name Toluifera Balsamum, is unsuitable, as
it indicates that it is the balsam-bearing Yoluifera, as if no other
species of Toluifera yielded any balsam. The Ph. Brit. name, Myrow- —
ylon Toluiferum, appears to be preferable—Pharm. J. 1916, v. 97,
p. 484. .
BELLADONNZ FOLIA.
Sievers, Arthur F.: The possibility of improving the commercial |
belladenna crop through selection—Am. J. Pharm. 1916, vy. 88, p. |
193-215: see also Chem. Abstr. 1916, v. 10, p. 1691.
Arny, L. Wayne: A short article on the cultivation of medicinal ~
plants, dealing principally with the cultivation of belladonna.—
Drug. Cire. 1916, v. 60, p. 597-801.
Wilson, J. Beetham: The results of experiments conducted by an —
English pharmacist on the cultiv cass of belladonna on waste lands
of England—Chem. & Drug. 1916, v. 88, No. 1905, p. 772-178.
Vaytte: Notes on the cultivation oe pelludonas near Petrograd,
Russia. These plants were found to contain principally hyoscya-
mine and only traces of atropine—J. pharm. et chim. 1916, v. 14,
p. 112-113; see also Répert. pharm. 1916, v. 28, part 1, p. 327 from”
Pharmazevtizeski J. 1916, p. 169.
Kilmer, Fred B.: A short description of the chemical and physio-
logical properties of the alkaloids of Amaryllis belladonna.—J. Am.
Fharm. Assoc. 1916, v. 5, p. 1202-1204.
Johannessen: A comparison of the methods of the Swiss, German, ~
and Norwegian pharmacopeeias for the evaluation of belladonna and |
hyoscyamus leaves. An abstract—Pharm. Ztg. 1916, v. 61, p. 116.
a «|
Oh
a
157
yan Itallie, L.: Notes on the determination of the alkaloids in bella-
onna leaves and belladonna extract.—Pharm. Weekblad, 1916, v.
93, p. 1664-1667.
| Dean, Harold: Of late belladonna leaves have been much adulter-
ited with the leaves of poke root, scopola or ailanthus, 20 to 80 per
rent of these materials having een found therein—J. Am. Pharm.
Assoc. 1916, v. 5, p. 537.
' E’we, G. E.: r sample of a drug closely resembling belladonna was
ee from alkaloids——Proc. Pennsylvania Pharm. Assoc. 1916.
Table showing reported variation in alkaloidal content of belladonna lcaves.
Number of samples—
Reporters. References,
Above Below
standard. | standard.
Dee ee eee
1 | Oil, Paint & Drug Rep. 1916, v. 90, No. 16, p. 46.
BME REALCD ccc scaccvecsss< 3 0} J. Am. Pharm. Assoc. 1916, v. 5, p. 536.
Slee Wtohorts.......-..-.-.--. 18 0 | Proe. Pennsylvania Pharm. Assoc. 1916, p. 119.
USI Se ee 6 0 | Oil, Paint & Drug Rep. 1916, v. 90, No. 16, p. 46.
. E. Vanderkleed.........--- 2 1| J. Am. Pharm. Assoc. 1916, v. 5, p. 536
-——
_ Joll, Mary E.: A report on three cases of belladonna poisoning.—
Lancet, 1916, v. 191, p. 647.
BELLADONNZ RADIX.
Schneider, Albert: The diameter for belladonna starch granules is
‘given as “0,003 to 0.030 mm.” (3 to 30 microns), whereas none meas-
' ure over 18 microns in diameter. If the measurements given have
reference to the compound starch granules, rather than to the single
or simple granules, it should have been so stated.—Drug. Cire. 1916,
-y. 60, p. 692.
Schneider, Albert: In tests for the identification of belladonna
root, the U. S. P. does not mention the distinctly eccentric position
of the hilum in the starch granules—Drug. Cire. 1916, v. 60, p. 693.
Vanderkleed, C. E.: The seven samples of belladonna root ex-
~ amined showed an alkaloidal content of 0.424 to 0.640 per cent.—J.
_ Am. Pharm. Assoc. 1916, v. 5, p. 537.
__Anon.: The mydriatic alkaloidal content of one sample of bella-
‘donna root assayed was below standard.—Proc. Pennsylvania Pharm,
Assoc. 1916, p. 119.
. BENZALDEHYDUM.
Umney, J. C.: The U. S. P. IX method for the determination of
benzaldehyde gives low results. The end point with methyl orange
is not sharp and the method can not be considered satisfactory.—
F Perf. & Ess. Oil Rec. 1916, v. 7, p. 344.
158
Wastenson, Hugo: A note on the adulteration of benzaldehyde—
Svensk farm. Tidskr. 1916, v. 20, p. 515.
Roberts, J. G.: One shipment of benzaldehyde examined proved
to be of inferior quality. It failed to comply with the U. S. P. spe-
cific gravity and boiling point requirements, and was only partly
soluble in a solution of sodium bisulphite—Proc. Pennsylvania
Pharm. Assoc. 1916.
BENZENE.
Anon.: An extract from a paper written by Michael Faraday in-
1825 telling of the discovery of benzene—Chem. & Drug. 1916, y.
88, p. 773.
Spielman, Percy E.: Descriptions of methods for the determina-
tion of benzene, toluene, paraffin, and carbon disulphine in commer-
cial benzoles.—Chem. & Drug. 1916, v. 88, p. 68.
Meldrum, Robert: An account of studies dealing with the vagaries
of benzene during solidification and fusion. The average solidify- —
ing point was found to be 5.6° C. and the average melting point
5.7° C.—Chem. News, 1916, v. 113, p. 267.
Editorial: The toxicology of benzene. A growing source of dan-
ger hes in the inhalation of benzene vapors.—J. Am. M. Assoc.
1916, v. 66, p. 432.
Barry and Ketcham: From a study of the literature and from
their experience with one case the authors conclude that benzene
is a valuable remedy in the treatment of chronic myeloid leukemia,
provided there are no complications and the disease is not of too
long duration.—J. Am. M. Assoc. 1916, v. 67, p. 904.
BENZINUM PURIFICATUM.
Rittman, Dutton, and Dean: A paper on the manufacture of gaso-
line and benzene-toluene from petroleum and other hydrocarbons.—
Chem. Abstr. 1916, v. 10, p. 1425 from Bull. U. S. Bur. of Mines,
1916, No. 114, p. 1-268.
Anon.: Poisoning from inhalation of benzine. Fatal cases are
said to be rare. Persons vary in susceptibility to the toxic effects
of benzine. Women are said to be more susceptible than men.—
J. Am. M. Assoc. 1916, v. 66, p. 209.
“ditorial: Hazards in handling gasoline. A review of the avail-
able literature for 1913 shows that 1,040 persons were burned to
death and 3,120 persons injured in the United States alone due to
carelessness in handling gasoline—J. Am. M. Assoc. 1916, v. 66,
p. 362-363,
BENZOINUM.
Holmes, E. M.: In a paper discussing the source of Siam benzoin,
it is stated that apparently the pharmacopesial authorities of the
United States do not accept the published botanical source of Siam
159
enz oin (Siyrax tonkinense, Craib), (Pharm. J. ser. 4, v. 37, p. 804),
$ it is ignored under the botanical source of eamaii of which the
jiam, as well as the Sumatra, kind is official—Pharm. J. 1916, v. 97,
9. 484.
- Rordorff, H.: From an examination of fruits believed to yield
Siam benzoin, it is concluded that the true source of this variety
hould still be regarded as Styrax tonkinese—Schweiz. Apoth.-Ztg.
1916, v. 54, p. 585-588.
E’we, G. E.: Three lots of benzoin examined failed to meet the
U. S. P. requirement of 75 per cent soluble in alcohol. They were
(0.5 per cent, 70.7 per cent, and 72.1 per cent, respectively.—Proe.
Pennsylvania Pharm. Assoc. 1916.
Roberts, J. G.: A five-case-lot of benzoin examined proved to be of
“unsuitable quality, containing only 60.75 per cent of alcohol-soluble
matter—Proc. Pennsylvania Pharm. Assoc. 1916, p. 110.
_ Scoville, W. L.: Six lots of gum benzoin examined yielded 78 to
87.3 per cent of alcohol-soluble constituents—J. Am. Pharm. Assoc,
between 67. 8 and 16.5 per cent in 3 alcohol caluble mnakter and ae
0.96 to 1.62 per cent of ash.—J. Am. Pharm. Assoc. 1916, v. 5, p. 537,
BENZOSULPHINIDUM.
- Klostermann, M., and Scholta, K.: A method for the detection
and estimation of saccharin in the presence of other substances is
| described.—Ztschr. Unters. Nahr-Genussm. 1916, v. 31, p. 67-68,
through Analyst (The), 1916, v. 41, p. 309-310.
‘E’we, G. E.: Two lots of saccharin examined contained 0.22 per
| cent and 0.5 per cent of ash, respectively, but were otherwise U. S. P.
| One lot was the sodium salt, and another lot labeled “ crystal saccha-
rin” was also the sodium salt.—Proc. Pennsylvania Pharm. Assoc.
1916, p. 117.
@ BERBERIS, N. F.
_ Anon.: A short note giving information relative to the cultivation
_ of Oregon grape in America.—N. A. R. D. J. 1916, v. 21, p. 215.
BETAEUCAINE HYDROCHLORIDUM.
Orr, T. G.: A report of a case of betaeucaine poisoning, with ref-
erences to six cases of betacucaine intoxication found in the litera-
‘ture—J. Am. M. Assoc. 1916, v. 66, p. 1857.
BETANAPHTHOL.
Stortenbeker, W.: Notes on the crystal forms of the two naph-
_ thols—Chem. Abstr. 1916, v. 10, p. 1645, from Ztschr. Kryst. Min,
- 1916, v. 55, p. 373-374; see also H. Steinmetz, ibid. p. 373-376.
160
Denigés, G.: Notes on the use of sulphotitanic acid as a reagen
for eanpaidhan between a- and ¢-naphthol—Ann. gael analyt
1916, v. 21, p. 216-217. e.
Rsberis, J. G.: One lot of betanaphthol was rejected as it was ne
U. S. P. It had an objectionable odor, contained alphanaphthol
was slightly acid to litmus, and yielded 0.09 per cent of residue upor
ignition.—Proc. Pennsylvania Pharm. Assoc. 1916, p. 110.
Anon.: Betanaphthol tablets are stated to be successfully used in
the treatment of hookworm.—Chem. & Drug. 1916, v. 88, p. 37.
BISMUTHI BETANAPHTHOLAS.
Murray, B. L.: A description of an electrolytic method for @
determination of bismuth in bismuth betanaphthol—J. Ind. & Eng g.
Chem. 1916, v. 8, p. 257-258,
BISMUTHI SUBGALLAS.
Merieux: The local application of a mixture of bismuth subgallate
with dried serum, made to the wound six hours after inoculation
was found to arrest the evolution of tetanus in the guinea pig. A
abstract—Pharm. J. 1916, v. 96, p. 555.
BISMUTHI SUBNITRAS.
Bockmann, P. W. K.: A report of investigations dealing with the
behavior of bismuth subnitrate toward diluted acids.—Archiv. exper.
Path. u. Pharmakol. 1916, v. 80, p. 140-145.
Robertson, A.: In a mixture containing bismuth subnitrate and
sodium bromide, the bismuth salt was reduced upon standing.—Chem,
Abstr. 1916, v. 10, p. 1404 from Pharm. Weekblad, 1915, v. 52, p. 945.
Higgins, Wm. H.: A report on the toxicity of bismuth salts.—J, |
Am. M. Assoc. 1916, v. 66, p. 648-650.
BROMUM, N. F.
Moles, Enrique: A revision of the atomic weight of bromine based —
on the normal density of hydrogen bromide gas.—J. chim. phys.
1916, v. 14, p. 389-444,
Scott, Alexander: Dry bromine, prepared by distillation over
anhydrous barium oxide, boiled at 57.9° C. under a pressure of 739
mm.—Chem. & Drug. 1916, v. 88, p. 76. |
Waller, Elwyn: Notes on the procedure to be followed in examining
samples of commercial bromine.—J. Ind. & Eng. Chem. 1916, v. 8,
p. 837-838. .
Norton, Thomas H.: The reopening of the bromine wells in and
about Pomeroy, Ohio, and Mason City, W. Va., will increase the
present monthly production of bromine by about 5 to 6 tons.—Com- 7
Rep. 1916, No. 6, p. 98.
161
BRYONIA, N. F.
Jensen, M. B.: Bryony root is more toxic when fresh than when
dried. It contains two glucosides—bryonine, soluble in water but
nactive, and bryonidine, insoluble in water but which paralyzes the
lervous system.—J. pharm. et chim. 1916, v. 13, p. 25, from Pharm.
J. 1915, p. 641, from Rostock Inst. Pharm. Physiolog. Chem.
BUCHU.
| Rusby, H. H.: A number of shipments of spurious buchu, repre-
senting several species, have been received. On investigation it was
and that the error was ane to the ignorance of the collectors.—J
Am. Pharm. Assoc, 1916, v. 5, p. 587.
Anon.: In discussing the- ce of buchu, it is stated that 19
varieties of Barosma are commercially available in the Port Eliza-
beth district, South Africa, and that 3 of these when submitted to
London for testing were reported to possess the properties of
|B. betulina—Oil, Paint & Drug Rep. 1916, v. 90, No. 14, p. 83.
| Flexer, Fayette J.: Some notes on South African buchu and other
' medicinal plants.—-Com. Rep. 1916, No. 229, p. 1207.
» Sayre, L. E.: A sample of puelty examined was rejected, as it
was not up to standard.—Bull. Kansas Bd. Health, 1916, p. 10.
CACAO PRAEPARATA, N. F.
Hoekstra, S. W.: A review of the cocoa trade and industry of the
_ Netherlands.—Com. Rep. 1916, No. 138, p. 982-984.
Savini, G.: Descriptions of methods for the determination of
_ theobromine and caffeine in cocoa and chocolate—Ann. chim. appli-
~ eata, 1916, v. 6, p. 247-250.
_ <Anon.: Directions for the examination of cocoa, with special
_ reference to the determination of abnormal amounts of cocoa shells.—
_ Chem. Ztg. 1916, v. 40, p. 969-970.
Lange, W.: A description of a method for the quantitative
- determination of the fat in cacao. The quantity of fat extracted
_ from nine samples ranged from 50.9 to 57.3 per cent. An abstract—
»C. U. C. P. Alumni J. 1916, v. 23, p. 220.
CAFFEINA.
Guglialmelli, L., and Palet, L. P. J.: Data showing the caffeine
content of maté by the Katz modification of the Keller and the
Beittner method.—Chem. Abstr. 1916, v. 10, p. 2007 from Anales
_ soe. cientifica Argentina, 1915, v. 80, p. 246-259.
Rollande, A. C., and Thevenon, L.: A report on the use of caf-
feine by malingerers to oe tachycardia.—J. pharm. et chim.
1916, v. 14, p. 824.
110095°—19——11
162
Nesbit, Edwin L.: Coffea cruda and caffeine. A discussion of 1
alimentary phenomena of a trial proving on healthy subjects.
Chem. Abstr. 1916, v. 10, p. 2113 from J. Amer. Inst. Homeopathy
1916, v. 8, p. 1412-1423. a
Editorial: The value of caffeine in the treatment of asthma. The
anticonstrictor effects of caffeine are too feeble to permit of its being
classed with the more familiar remedies adapted to the relief o:
typical asthmatic symptoms.—J. Am. M. Assoc. 1916, v. 66, p. 431-
432,
CALAMUS.
Roberts, J. G.: The whole of one shipment of calamus was in an.
unfit condition, as it contained a large portion of mouldy root.—Proe.
Pennsylvania Pharm. Assoc. 1916.
CALCII CARBONAS PRZECIPITATUS.
Smith, Carl E.: Notes on the U. S. P. tests for the identity an
purity of precipitated calcium carbonate—Am. J. Pharm. 1916,
v. 88, p. 215-216.
Vanderkleed, C. E.: Precipitated calcium carbonate C. P. usually
gives a slight precipitate in the test for limit of iron, aluminum, and
phosphates.—J. Am. Pharm Assoc. 1916, v. 5, p. 587.
CALCIT CHLGRIDUM.
Ritsert: Researches on the composition of compounds formed by
the action of calcium chloride on milk sugar.—Répert pharm. 1916,
v. 28, p. 5.
Vanderkleed, C. E.: One lot of calcium chloride examined left ”
1.4 per cent of residue in the U. S. P. test for magnesium and alka-_
lies, while the standard is only 0.1 per cent—J. Am. Pharm. Assoc.
1916, v. 5, p. 587.
Wilson, Harold: The treatment of hay fever with calcium salts.
Calcium chloride may be taken in doses of 3 gm. daily for an in- ©
definite time without any apparent injury and with material benefit
in a large percentage of cases—J. Am. M. Assoc. 1916, v. 66, p. 715=7
716, |
CALCIT GLYCEROPHOSPHAS.
Anon.: In a review of the U. 8. P. IX, regret is expressed for the ©
admission of calcium and sodium glycerophosphates, as their thera-.
peutic efficiency is in doubt at the present time.—J. Am. M. Assoe.
1916, v. 67, p. 764. q
Anon.: A discussion concerning the questionable therapeutic value
of the glycerophosphates.—J. Am. M. Assoc, 1916, v. 66, p. 1205- ©
1206.
163
_ Puckner, W. A.: Report of the council on pharmacy and chemistry
of the American Medical Association on the therapeutic value of
e glycerophosphates.—J. Am. M. Assoc. 1916, v. 67, p. 1033-1034,
Anon.: The H. K. Mulford Co. reports that solutions of calcium
elycerophosphate may be sterilized by heating at 70° for one hour
on (five) successive days without decomposition if the solution is ren-
dered acid to the extent of 0.2 per cent.—Drug. Cire. 1917, v. 61, No.
BO, p. 25.
CALCIL HYPOPHOSPHIS.
Marriott, W. McKim: The therapeutic value of the hypophos-
phites. From the experiments conducted it was concluded that the
hypophosphites possess no specific value as a source of phosphorus
' for the body.—Rep. Therap. Res. Com. 1916, v. 5, p. 103-111; see
also J. Am. M. Assoc. 1916, v. 66, p. 486-488.
_ fPuckner, W. A.: The report of the council on pharmacy and chem-
. istry of the American Medical Association on the hypophosphite
- fallacy.—J. Am. M. Assoc. 1916, 67, p. 760.
| Kolthoff, J. M.: A discussion of various methods in use for the
_ titration of the hypophosphites.—Pharm. Weekblad, 1916, v. 53, p.
| 909-916.
k CALCII LACTOPHOSPHAS, N. F.
_ Anon.: A reprint of the standards for calcium lactophosphate
_ proposed by the committee on unofficial standards—J. Am. Pharm.
| Assoc. 1916. v. 5, p. 86-87.
CALCIT PHOSPHAS PRAICIPITATUS, N. F.
_ E’we, G. E.: Two lots of calcium phosphate examined contained
_ excessive chlorides.—Proc. Pennsylvania Pharm. Assoc. 1916.
_ Vanderkleed, C. E.: One sample of precipitated calcium phos-
"phate examined contained chloride in excess of the U. S. P. allow-
~ ance.—J. Am. Pharm. Assoc. 1916, v. 5, p. 587.
CALCII SULPHAS EXSICCATUS.
_ Keane, L. A.: A study of the composition and properties of plaster
| of Paris—J. Phys. Chem. 1916, v. 20, p. 701-728.
_ Astrue and Canals: The influence of alcohol on the setting of plas-
' ter of Paris—Chem. Abstr. 1916, v. 10, p. 2027 from J. pharm. et
' chim. 1916, v. 18, p. 214-218.
CALCII SULPHIDUM CRUDUM.
_ Anon.: In a reference to the use of calcium sulphide as an antidote
_ for mercuric chloride poisoning, it is stated that J. H. Wilins of
_ Cincinnati, Ohio, was able to save the lives of animals when treat-
164 %
ment was begun as late as 48 hours after the poison had been admi n-
istered.—Canadian Pharm. J. 1916, v. 29, p. 486. .
Bretau, Pierre: A description of the methods of preparation a nd
the properties of phosphorescent calcium sulphide—J. pharm. et
chim. 1916, v. 18, p. 33-87.
CALENDULA, N. F.
Gregory, William M.: A discussion of the antiseptic properties of
calendula and its tincture——New York M. J. 1916, v. 104, p. 67.
CALUMBA.
Holmes, E. M.: The principle of quoting the name of the fir t
describer of a plant in parentheses after its name, as in the case of
Jateorhiza palamata (Lamarck) Miers, is so misleading and is so
wasteful of time that its use is-to be depreciated. Thus the name
Jateorhiza palamata does not, of course, occur in Lamarck’s work,
since he described the plant under the name Menispermum palma-
twm, and the insertion of Lamarck’s name can be no help to the stu-
dent or user of the Pharmacopeia in identifying the drug—Pharm. —
J. 1916, v. 97, p. 484.
CALX CHLORINATA.
Comte: A discussion of the volumetric assay of chlorinated lime, —
Javelle water and Dakin’s solution by the usual iodometric¢
method.—J. pharm. et chim. 1916, y. 14, p. 232.
“Wilson, J.: Comments on the value of a solution of chlorinated.
lime for the sterilization of grain. It is stated to be superior to mer-
curic chloride or formaldehyde for this purpose—Sci. Am. 1916,
Sept. 30, p. 297.
Anon.: Of 23 samples of chloride of lime examined, 10 were found —
to be below standard.—Rep. Connecticut D. & F. Com. 1916, p. 19.
Casey, F. W.: Two samples of chlorinated lime examined were ”
rejected for being below standard.—Bull. Michigan D. & F. Dept.
1916, No. 252-255, p. 19. 3
Patch, E. L.: The available chlorine in the six samples of chlor-
inated lime examined ranged between 8 and 34 per cent.—J. Am.
Pharm. Assoc. 1916, v. 5, p. 540.
Street, J. P.: Of 25 samples of chlorinated lime examined, only 3
were found to be of full strength. The U. S. P. requires that chlori-
nated lime should contain not less than 30 per cent of available chlo- _
rine.—J. Am. M. Assoc, 1916, v. 67, p. 695.
Todd, A. R.: Of 13 samples of chlorinated lime examined, 8 were
rejected for not complying with the U. S. P. standard.—Bull. Michi- —
gan D. & F, Dept. 1916, No. 244-247, p. 20.
165
CAMPHORA.
_ Anon.: A note on the history of camphor.—Perf, & Ess. Oil Ree.
1916, v. 7, p. 145-146.
Bohrisch: The author describes a color reaction with vanillin-
hydrochloric acid and sulphuric acid which can be used as a test for
_ the identification of natural camphor. An abstract—Drug. Cire.
- 1916, v. 60, p. 20.
Parry, Ernest J.: The U. S. P. statement, “the specific rotation
[a]p of camphor in a solution in alcohol at 25° C. is between -++-41°
and +42° in a 200 mm. tube, containing 10 gm. of camphor in each
100 mils of solution,” is said to be incorrect as the specific rotation
is the same regardless of the length of the tube. Furthermore, the
directions to use alcohol of “about 95 per cent” are unfortunate, as
the specific rotation varies greatly with the strength of the aleohol.—
Chem. & Drug. 1916, v. 88, No. 1913, p. 40.
Anon.: The new edition of the Finnish pharmacopeia specifies
that camphor should melt at 175° to 178° C.—Am. Perf. 1916, v. 11,
p. 94.
Umney, J. C.: Experimental data on the optical rotation of cam-
phor in alcoholic solution.—Perf. & Ess. Oil Ree. 1916, v. 7, p. 46;
see also Chem. Abstr. 1916, v. 10, p. 1403.
Joachimoglu, Georg: A comparative study of the action of d-, L,
and i-camphor revealed the fact that there was no difference in the
toxicity of these different forms.—Physiol. Abstr. 1916, v. 1, p. 429
from Arch. exper. Path. u. Pharmakol. 1916, v. 80, p. 1-7.
Likhatcheva, M. P.: A report of researches to determine the action
of camphor and menthol on the coronary and peripheral vessels,
An abstract—J. Am. M. Assoc. 1916, v. 67, p. 843.
Leone, Gustavo: A study of the pharmacodynamic action of cam-
phor upon the circulation and on the isolated heart.—Arch, farmacol.
sper. 1916, v. 21, p. 370-892.
CAMPHOR-MENTHOL, N. F.
Wimmer, Curt P.: Some experiments with proposed formulas for
camphor ice.—Midl]. Drug. 1916, v. 50, p. 63-65; see also Chem.
Abstr. 1916, v. 10, p. 1405.
Anon.: A formula for the preparation of glycerin camphor ice is
presented. An abstract—Drug. Cire. 1916, v. 60, p. 210.
CANNABIS.
Rusby, H. H.: The genuine cannabis indica of former days has be-
come rather unusual, various forms of cannabis herb, often very
seedy, from various countries having replaced it—J. Am. Pharm.
Assoc. 1916, v. 5, p. 537.
166
Anon.: Bulletin No. 8 of the chemical section of the Wellcome
Tropical Research Laboratories at Khartoum is stated to contai ng
descriptions of tests for hashish——Chem. & Drug. 1916, v. 88, No.
1875, p. 46. |
Pearson, W. A.: In discussing the physiological standardization of
cannabis, the author gives his experience in regard to the difference
of the susceptibility of dogs, and proposes that the chairman of the
committee on physiological testing prepare a composite standard |
fluid extract of cannabis which has been obtained from several ©
sources, and that portions of this standard fluid extract be sent to the
various laboratories where physiological standardization is carried _
out.—J. Am. Pharm. Assoc. 1916, v. 5, p. 1194-1195. :
Benedict, A. L.: A discussion of the toxic effects of cannabis as
shown by the treatment of 20 cases.—Therap. Gaz. 1916, v. 40, p.
758-759.
Burr, Chas. W.: A description of the effects produced as a result —
of intoxication with cannabis indica—Therap. Gaz. 1916, v. 40, p.
554-556.
Tobler, Walther: From experiments, it is concluded that the
diuretic constituent of cannabis is cannabinol.—Chem. Zentralbl.
1916, v. 1, p. 1170.
CANTHARIS.
Rogers, T. B.: A report of a study of cantharides and of the
cerate of cantharides—Mulford’s Vet. Bull. 1917, v. 8, p. 70-72.
Hintz, H.: A discussion of the advisability of substituting can- —
tharidin for some of the galenical preparations of cantharides,—
C. U. C. P. Alumni J. 1916, v. 23, p. 35.
Anon.: The cantharidin content of five samples of Chinese can-
tharides assayed was above standard.—Proc. Pennsylvania Pharm.
Assoc. 1916, p. 119.
Scoville, W. L.: The cantharidin content of the samples of can-
tharides examined ranged from 0.55 to 1.15 per cent.—J. Am. ~
Pharm. Assoc. 1916, v. 5, p. 537. .
Vanderkleed, C. E.: Six samples of Chinese cantharides examined
ranged from 0.570 to 1.10 per cent in cantharidin content.—J. Am.
Pharm. Assoc. 1916, v. 5, p. 537.
CAPSICUM.
Atkins, W. R. G., and Sherrard, G. O.: A report of researches
to determine the nature and composition of the pigments of cap-
sictun fruits. An abstract.—J. Roy. Micros. Soe. 1916, part I, p. 88.
Scoville, Wilbur L.: African chillies are specified in the U. S. P. —
IX because they are usually more pungent than the Japanese and —
ave more desirable as therapeutic agents.—Bull. Pharm. 1916, vy. —
30, p. 363. :
167
_ Rusby, H. H.: Capsicum is now defined as Capsicwm frutescens
_L., under which name are included a great number of forms, many
_ of them entirely unserviceable for the medicinal uses to which cap-
- sicum is applied.—Drug. Cire. 1916, v. 60, p. 537.
Lilly, J. K.: Six lots of capsicum offered as U. S. P. were made
_ up of African and Bombay capsicum and paprika—Oil, Paint &
Drug Rep. 1916, v. 90, No. 16, p. 46.
Sayre, L. E.: Of two samples of powdered capsicum examined,
one was rejected —Bull. Kansas Bd. Health, 1916, p. 12.
Anon.: The oleoresin content of one sample of capsicum assayed
was above standard.—Proc. Pennsylvania Pharm. Assoc. 1916, p.
119.
Vanderkleed, C. E.: The oleoresin content of the six samples of
capsicum examined ranged from 13.85 to 20.84 per cent.—J. Am.
Pharm. Assoc. 1916, v. 5, p. 587.
CARAMEL, N. F.
Lichtardt, G. H. P.: A short discussion of the applications of the
author’s test for the identification of caramel—J. Am. Pharm.
Assoc. 1916, v. 5, p. 294.
Carles, P.: Commercial samples of caramel sometimes contain
sodium carbonate. The latter is added for the purpose of making
the brown color more pronounced and for increasing the density of
the syrup prepared therefrom.—Répert. pharm. 1916, v. 28, part 1,
p. 286-287.
CARBO ANIMALIS.
Anon.: Analytical data showing the difference in the composi-
tion of animal charcoal, molasses charcoal, and blood charcoal.—
Pharm. Post, 1916, v. 41, p. 765.
Thorne, Percy C. L.: A study of the methods of preparation and
q properties of colloidal carbon.—J. Chem. Soc. Lond. 1916, v. 109,
p. 202-209.
Wickenden, Leonard, and Hassler, John W.: A description of a
rapid method for comparing the decolorizing efficiency of charcoals.—
J. Ind. & Eng. Chem. 1916, v. 8, p. 518-519.
Joachimoglu, Georg: A report of experiments to determine the
absorption capacity of animal charcoal. A method for carrying out
this determination is described in detail—Biochem. Ztschr. 1916, v.
77, p. 1-138.
Knecht, E., and Hibbert, E.: From experiments, it is concluded
that the nitrogen content, as well as the state of aggregation of animal
charcoal, is a factor influencing the absorption of coloring matters.—
Physiol. Abstr. 1916, v. 1, p. 341.
168
Weinrich, M.: An apparatus for revivifying bone black or other —
filtering material. U. S. Patent No. 1,184,398, May 23.—Chem. |
Abstr. 1916, v. 10, p. 1780.
Strauss, ae: The influence of blood charcoal on peptic digestion.
Evidence is presented to prove that, although absorption of the
digestive ferments proceeds in the test tube, the living digestive
apparatus tends to keep the quantity of unabsorbed ferments at a —
level which permits of norma] digestion taking place——Deutsch. med.
Wehnschr. 1916, v. 42, p. 836-38; see also Chem. Abstr. 1916, v. 10, p.
1044,
CARBONEI DISULPHIDUM.
Denigés, G.: Descriptions of certain microreactions for carbon
disulphide.—Ann. chim. analyt. 1916, v. 21, p. 69.
Editorial: Carbon disulphide as an industrial poison. Dr. Alice
Hamilton in a recent investigation discovered cases of carbon disul-
phide cyanosis among the vulcanizers of rubber and the splicers of
inner tubes for tires.—J. Am. M. Assoc. 1916, v. 66, p. 357,
CARDAMOMI SEMEN.
Anon.: The dried cardamom seeds only are official, but the druggist
should purchase the whole fruit and remove the seeds himself in order
to avoid obtaining an adulterated product.—N. A. R. D. J. 1916, v.
23, p. 461.
Lilly, J. K.: Three lots of cardamon examined were found to be
partially extracted and one consisted of wild cardamom seed.—Oil,
Paint & Drug Rep. 1916, v. 90, No. 16, p. 46.
CARUM.
Rosendahl, H. V.: Remarks on wild caraway and the volatile oil
obtained therefrom by distillation.—Svensk farm. Tidskr. 1916, y. 20,
p- 1-2.
Roberts, J. G.: Three lots of caraway seed examined contained
0.35, 0.57, and 0.31 per cent., respectively, of foreign matter and
vielded 7.28, 7.17, and 8.23 per cent of ash.—Proc. Pennsylvania
Pharm. Assoc. 1916,
CARYOPHYLLUS.
Anon.: A note on the history and distribution of cloves.—Perf. &
Fs. -Oil Rec. 1916, v. 7, p. 20.
Folpmers, T.: Data obtained in the determination of moisture in.
cloves by the direct and indirect methods are presented.—Chem.
Weekblad, 1916, v. 18, p. 14-16.
169
akota F. & D. Com. 1916, No. 16, p. 134-135.
CASCARA SAGRADA.
Woodward, G. C.: A consular report describing the collection of
seara bark in British Columbia.—Com., Rep. 1916, No. 214, p. 966.
Rusby, H. H.: The fanciful name “cascara sagrada” has been sub-
jtuted as the Latin title for Rhamnus purshiana, which latter is as
re Latin as the former is Spanish.—Drug. Cire. 1916, y. 60, p. 537.
Schneider, Albert: The color of powdered cascara sagrada bark
given by the U. S. P. as “light brown to olive brown.” This
wder is brown with yellow, the brown predominating, henes
ellowish-brown.— Drug. Cire. 1916, y. 60, p. 693.
~Gathercoal, E. N.: The adulterant of cascara bark noted by
*. A. Miller in 1912 has been identified as the bark of Prunus padus.
Phis bark is a commercial article in Germany, according to E. M.
Holmes, and has been received in England as a substitute for wild
cherry bark—J. Am. Pharm. Assoc. 1916, v. 5, p. 803.
| Webster, Herbert T.: A comparison of the therapeutic uses of
Rhamnus purshiana and Rhamnus californica—J. Am. Vet. Med.
ssoc. 1916, v. 49, p. 379-382.
CASCARILLA, N. F.
| Rusby, H. H.: Cascarilla bark has become very poor in quality,
being mostly the scrapings of small limbs and twigs. It would
appear that this shrub is now almost exterminated in the wild
state—J. Am. Pharm. Assoc. 1916, v, 5, p. 537.
CASTANEA, N. F.
Tunmann, O.: Researches on the extraction and microdetection
of sculin in horse-chestnut bark.—Schweiz. Apoth.-Ztg. 1916, v, 54,
p. 45-67.
Pollak, Leopold: A report of researches relating to the indenti-
fication of the extract of chestnut wood. An abstract.—Chem.
Zentralbl. 1916, v. 87, part 1, p. 441-442.
CAULOPHYLLUM, N. F.
Anon.: A short note giving information relative to the cultiva-
of blue cohosh in America.—N. A. R. D. J. 1916, v. 21, p. 215.
170 q
CERA ALBA. %
Verda, A.: A description of a color reaction with copper f or t
detection of stearin in wax.—Répert. pharm. 1916, v. 28, part 1,3
208.
CERA FLAVA.
Salamon, M. S.: A discussion of data obtained in the samplin
and analysis of beeswax.—J. Soc. Chem. Ind. 1916, v. 35, p. o
Richardson, F. W., and Bracewell, G. A.: A discussion of ¢
analysis of waxes, ai special reference to beeswax and wool wax.
J. Soc. Chem. Ind. 1916, v. 35, p. 160-163. a
Fabris, U.: Data howine the viscosity of beeswax at 100° ¢
using an Ostwald’s viscosimeter. The author states that this 01
stant may be of value in detecting impurities where other constan
fail—Ann. Falsif. 1916, v. 9, p. 100; see also Chem. Abstr. 191
y. 10, p. 2411. |
Ryan, Hugh, and Dillon, T.: From experiments, the authors co i
clude that the “ potash-lime method” for determining hydrocarbo :
in beeswax yields results which are too high.—Nature, 1916, vy. 96,
p. 668.
Brill, Harvey C., and Agcaoili, Francisco: A comparison of t
ETE of Pinion beeswax with the Japanese and Koreans
Philippine J. Sc. 1916, v. 11, see. a, p. 15-18.
Smith, F. Willoughby: According to figures obtained from thi
Agricultural Society of the Caucasus, the total production of be
wax in Russia reaches on the average 8,847,638 pounds per year
Com. Rep. 1916, No. 77, p. 7.
Anon: A note on the adulteration of Indian beeswax with par
affin.—Chem. & Drug. 1916, v. 88, p. 253. d
Congdon, Leon A.: Of thr ee samples of yellow wax ——
was rejected.—Rep. Kansas Bd. Health, 1916, p. 133. E
Lilly, J. K.: Samples of beeswax examined were found to be ad
terated with ceresin—Oil, Paint & Drug Rep. 1916, v. 90, No. |
p. 46.
Sayre, L. E.: A sample of yellow wax examined was adulterat
with paraffin and contained fatty acids—-Bull. Kansas Bd. Heal
1916, v. 12, p. 12.
CEREVISIZ, FERMENTUM COMPRESSUM, N. F.
Neuberg, Carl: A study of the chemical constitution of yeast pi
tein.—Physiol. Abstr. 1916, v. 1, p. 280, from Chem. Zentralbl. 1
v. 1, p. 162-163.
Bokorny, Th.: A report of researches showing the presence 0/7
emulsin and myrosin in compressed yeast from the Munich brew
and also in baker’s yeast.—Physiol. Abstr. 1916, y. 1, p. 391-392,
<u
171
Gregg, H.: A report of experiments to determine the value of yeast
sa food. Yeast extract is stated to be an excellent substitute for
neat extract. An abstract.—Apoth.-Ztg. 1916, v. 31, p. 24.
Salomon, H.: A discussion of the use and value of yeast as an
rticle of diet—Physiol. Abstr. 1916, v. 1, p. 328; see also H. Wintz
nd Max Rubner, Physiol. Abstr. 1916, v. 1, p. 288.
CERIIT OXALAS.
Wilcox, Reynold W.: A discussion of cerium, with special refer-
ence to the therapeutic uses of the oxalate. —New York M. J. 1916,
y. 104, p. 836-838.
CETACEUM.
Frerichs, G.: A discussion of the tests for spermaceti. The tests
Jaid down in the Ph. Germ. are inadequate. More reliable tests are
‘described.—Chem. Zentralbl. 1916, v. 2, p. 282, from Apoth.-Ztg.
1916, v. 31, p. 209-210.
Lundin, P. E.: The determination of the specific gravities of 10
samples of spermaceti by the hydrostatic method showed this con-
stant to vary from 0.931 to 0.949. This method is stated to be more
satisfactory than the floating method prescribed by most pharma-
copeias— Pharm. Weekblad, 1916, v. 58, p. 1000.
CHIONANTHUS, N. F.
_ Anon.: A short note giving information relative to the production
and collection of fringe-tree bark in America.—N. A. R. D. J. 1916,
y. 21, p. 1114.
CHONDRUS.
- Holmes, E. M.: The Gigartina mamillosa of J. Agardh is given
us one of the sources of the drug. This is an improvement, for it is
practically impossible, when collecting Chondrus erispus, to avoid
gathering some pieces of Gigartina, and consequently these are
always present in commercial samples.——Pharm. J. 1916, v. 97, p. 484.
Rusby, H. H.: Great quantities of chondrus have arrived in an
| It is usually imported as “French moss” or “ crude moss.”—J. Am.
“Pharm. Assoc. 1916, v. 5, p. 538.
CHROMII TRIOXIDUM.
172
CHRYSAROBINUM.
Holmes, E. M.: Chrysarobin is attributed to Voucapoua Ararobe
(Aguiar), Druce. This name was never used by Aguiar. He de
scribed the plant as Andira Araroba, and the use of Voucapoua i
therefore to be deprecated as serving no useful purpose-—Pharm., J
1916, v. 97, p. 485.
Editorial: Chrysarobin, widely used in the treatment of psoriasis
is manufactured from goa or araroba powder, which is said to come
entirely from the American continent—from the State of Bahia
Brazil—J. Am. M. Assoc. 1916, v. 66, p. 1784-1785.
Eder, Robert: A report of an investigation relative to the con-
stituents of commercial chrysarobin.—Chem. Zentralbl. 1916, v.
p. 978-979 from Archiv. Pharm. 1916, v. 254, p. 1-33.
CINCHONA.
Anon.: Statistical notes dealing with the production of cinchona~
bark and quinine sulphate in India—Oil, Paint & Drug Rep. 1916
v. 90, No. 26, p..‘72.
Editorial: Notes on the introduction of cinchona trees in India,
.Brit,, M. J..1916, v. 1, p. 247.
van Itallie, L.: Notes on the quantitative determination of alka-
loids in cinchona bark and of the extract of cinchona.—Pharm,
Weekblad, one vy. 53, p. 1667-1671. 3
Lenci: osaeecon of a method for the alkaloidal assay of cin=
‘chona w Vee the alkaloids are precipitated with an excess of picri¢
acid and the excess of the latter titrated with nitron—Chem. & Drug.
1916, v. 88, p. 40.
Montemartini, C., and Bovini, F.: Data showing the influence of
temperature on the rotatory power of mixtures of cinchona alka:
loids.—Gaz. Chim. Ital, 1916, v. 46, p. 153-171.
Kaufmann, Adolph, et al.: A report of researches dealing with the
degradation eeialiae of the cinchona alkaloids—Ber. deutsch. chem
Gesellsch. 1916, v. 49, p. 2299-2310.
Anon.: The total anhydrous alkaloidal content of six samples o}
yellow cinchona assayed was above standard.—Proe. Pennsylvani
Pharm. Assoc. 1916, p. 119.
Clampett, G. W.: Two samples of cinchona bark examined con
tained 3 per cent total alkaloids and 2.3 per cent ether alkaloids,
respectively —Proc. Texas Pharm. Assoc. 1916, p. 80. .
Lilly, J. K.: Three lots of cinchona examined were low in alka
loidal content.—Oil, Paint & Drug Rep. 1916, v. 90, No. 16, p. 46.
Swift, . G.: Of 15 samples of cinchona bark examined, 2 con
tained 0.5 per cent of ether-soluble alkaloids, or less; 1 contained 0.8
173
per cent; 6 contained between 1 and 2 per cent, and 4 above 5 per
_cent.—Oil, Paint & Drug Rep. 1916, v. 90, No. 16, p. 46.
Vanderkleed, C. E.: The 10 lots of yellow cinchona examined
varied in alkaloidal content from 6.5 to 11 per cent.—J. Am. Pharm.
Assoc. 1916, v. 5, p. 538.
CINCHONA RUBRA.
Anon.: The total anhydrous alkaloidal content of 27 samples of
red cinchona assayed was above standard.—Proc. Pennsylvania
Pharm. Assoc. 1916, p. 119.
Lilly, J. K.: Two lots of red cinchona examined were found to be
below the U.S. P. requirements for alkaloidal content—Oil, Paint &
Drug Rep. 1916, v. 90, No. 16, p. 46.
Roberts, J. G.: One lot of cinchona (red) examined contained 7.29
per cent of anhydrous cinchona alkaloids—Proc. Pennsylvania
Pharm. Assoc. 1916.
CINNAMOMUM SAIGONICUM.
Schneider, Albert: The length of the bast fibers of Saigon cinna-
mon is given as “ from 0.30 to 1.50 mm.” (30 to 1,500 microns) in the
U.S. P., whereas none attain a length to exceed 150 microns. If the
_ measurements given pertained to groups of bast cells rather than to
- individual bast cells, it should have been so stated.—Drug. Circe. 1916,
vy. 60, p. 692.
von Fellenberg, P.: A method for the estimation of cinnamic
aldehyde in cinnamon depends on the coloration which develops
_ when the aldehyde is treated with sulphuric acid and isobutyl] alco-
hol. An abstract—Analyst (The), 1916, v. 41, p. 274-275.
Holmes, E. M.: Notes on the sources, botanical, and commercial, of
cassia and cinnamon barks.—Perf. & Ess. Oil Rev. 1916, v. 7, p. 14-17.
_ Anon.: A reprint of an account of the collection of cinnamon bark
_ as given by the Greek historian Herodotus.—Perf. & Ess. Oil Ree.
» 1916, v. 7, p. 40.
Lilly, J. K.: One lot of Saigon cinnamon examined consisted of
Cassia cinnamon.—Oil, Paint & Drugs Rep. 1916, v. 90, No. 16, p. 46.
| Lea, E. J.: Samples of cinnamon examined contained exhausted
_ and worthless ground cinnamon bark.—Bull. California Bd. Health,
1917, v. 12, p. 231.
Frary, Guy G.: All of the six samples of powdered cinnamon ex-
amined were of standard quality Rep. South Dakota F. & D. Com.
1916, No. 16, p. 134.
COCA.
. Anon.: The ether-soluble alkaloidal content of six samples of coca
leaves assayed was above standard.—Proc. Pennsylvania Pharm.
_ Assoc. 1916, p. 119.
174
COCAINA. f
Harman, N. B.: A description of a method for preparing stable
solutions of cocaine and homatropine. —Brit. M. J. 1916, v. 2, p. 178.
Roth, G. B.: A comparison of the toxicity of cocaine aad novo-
caine.—Bull. Hyg. Lab. 1916, No. 109.
Editorial: Aside from its action as a local anesthetic, cocaine pro-
duces three conditions which have especially aroused the interest of
clinicians and pharmacologists. These are the dilation of the pupil,
the local constriction of certain blood vessels, and the acceleration of
the heart sometimes seen in cases of poisoning by this drug.—J. Am. |
M. Assoc. 1916, v. 66, p. 195-196.
Painter, A. M.: Comments on the employment of cocaine anes-
thesia for submucous resection of the nasal septum.—J. Am. M,
Assoc. 1916, v. 66, p. 114.
COCAINZ HYDROCHLORIDUM.
Virden: The author states that frequent or even prolonged boiling
of solutions of cocaine hydrochloride does not impair or destroy their
anesthetic value. An abstract.—Drug. Cire. 1916, v. 60, p. 212.
Reutter, L.: A note calls attention to the incompatibility of co-
caine hydrochloride with benzoate of mercury. An abstract.—
Pharm. Zentralh. 1916, v. 57, p. 9.
COCCUS.
Styles, George K.: A consular report of the prospects for the —
year’s crop of cochineal in the Canary Islands—Com. Rep. 1916, No.
150, p. 1172.
Roberts, J. G.: The ash yield of six samples of cochineal examined ©
ranged from 3.67 per cent to 5.47 per cent.—Proc. Pennsylvania
Pharm. Assoc, 1916.
CODEINA.
Carlinfanti, E.: Description of colorimetric methods for the de-~
termination of minute quantities of morphine and codeine. Fo
codeine, the blue color produced with ferric chloride is the basis of
the assay.—Chem. Abstr. 1916, v. 10, p. 1909.
Tunmann, O.: Methods for the microchemical distinction of mor-
phine and codeine.—J. Chem. Soc. 1916, v. 10, p. 655 from Apoth.-
Zte. 1916, v. 31, p. 148.
CODEIN 2 PHOSPHAS.
Duncan, William: Attention is directed to the fact that a 5 pe
cent solution of codeine phosphate precipitates on the addition of
ammonia water, and that the Ph. Brit. statement to the contrary i
wrong.—Pharm. J. 1916, v. 96, p. 352.
175
_ Anon.: A note on the incompatibility of codeine phosphate with
alkali bromides.—Am. Drug. 1916, v. 64, p. 224.
COFFEA TOSTA, N. F.
Sayre, L. E.: In experimental researches on the volatile principles
of roasted coffee, the author succeeded in isolating and identifying
pyridine.—Bull. Pharm. 1916, v. 80, p. 276-278; see also Chem.
Abstr. 1916, v. 10, p. 2250.
Anon.: Observations on the nature of the fermentation that takes
place in tea, cocoa, coffee, and tobacco.—Siidd. Apoth.-Ztg. 1916, v.
/56, p. 12.
Editorial: Coffee is one of those dietary adjuncts which modern
man has employed, like tea, alcohol, tobacco—and, perhaps, one
ought to add the ubiquitous chewing gum—presumably to increase
the pleasure of his existence quite independently of any need which
they might serve in the organism.—J. Am. M. Assoc. 1916, v. 66,
_p. 120.
% COLCHICI CORMUS.
E’we, G. E.: Of four samples of colchicum corm assayed, the col-
_ chicine content of one was above standard and three below.—Proc.
Pennsylvania Pharm. Assoc. 1916, p. 119.
_ Roberts, J. G.: Each of two lots of colehicum corm examined con-
tained 0.85 per cent of colchicine——Proc. Pennsylvania Pharm.
_ Assoc. 1916, p. 111.
4 COLCHICI SEMEN.
Umney, J. C.: Data relative to the sugar and extractive content of
' colchicum seed.—Pharm. J. 1916, v. 41, p. 393.
_ E’we, G. E.: The colchicine content of three samples of colchicum
seed assayed was above standard.—Proo. Pennsylvania Pharm.
Assoc. 1916, p. 119.
_ Roberts, J. G.: The following amounts of colchicine were found in
- four lots of colchicum seed examined: 0.57, 0.81, 0.71, and 0.68 per
- eent.—Proe. Pennsylvania Pharm. Assoc. 1916, p. 111.
COLCHICINA.
Merck, E.: Some data on the chemical and physical properties of
“pure colchicine. An abstract.—Chem. & Drug. 1916, v. 88, p. 40.
Vanderkleed, C. E., and E’we, G. E.: The melting point of col-
| chicina is difficult to observe because the fused alkaloid does not form
a meniscus in the melting-point tube, as occurs with most compounds,
Sout forms globules or wets the inside of the tube. If the point at
which a meniscus is formed is taken as the melting point, the tem-
perature observed will be high. For instance, a sample of colchicina
176
formed globules at 144° C., but did not form a meniscus in the tube
until a temperature of 160° C. was reached.—J. Am. Pharm. Assoe.
1916, v. 5, p. 715-716. :
Vanderkleed, C. E.: The colchicine on the market contains ex
cessive amounts of chloroform and mcisture. In 12 lots examined,
the loss in weight on heating at 102° C. was from 2.2 to 29.2 per
cent.—J. Am. Pharm. Assoc. 1916, v. 5, p. 538.
E’we, G. E.: Colchicine continues to show a large loss on heating
at 100° C., amounting to as high as 25.7 per cent. The loss is chiefly
chloroform.—Proe. Pennsylvania Pharm. Assoc. 1916, p. 111.
COLOCYNTHIS.
Swift, E. G.: Most of the colocynth on the market consists of the
pulp Sigh has been gathered after the fruit has reached the age
where the seeds turn brown.—Oil, Paint & Drug Rep. 1916, v. 90,
No. 16, p. 46.
CONDURANGO, N. F.
Lilly, J. K.: One lot of an unknown bark was offered as con
durango.—Oil, Paint & Drug Rep. 1916, v. 90, No. 16, p. 46.
COPAIBA.
Parry, Ernest J.: Much work has been done on copaiba during
recent years, but in spite of the fact that the refractive index and
optical rotation of the oil are well defined and known, the U. 8. P.
gives no refractive index at all, and the optical rotation is merely
given as “not less than —7°.” The acidity limits of 28 to 95 appear
to be too wide even for genuine Para balsam.—Chem. & Drug. 1916
y. 88, No. 1913, p. 40.
Beckers, W.: The author reports on the quality of eight Germ n
samples of copaiba balsam dispensed in capsules. An abstract.
C. U. C. P. Alumni J. 1916, v. 23, p. 186.
COPTIS, N. F.
Anon.: A short note giving information relative to the cultiva-
tion of goldthread in America.—N,. A. R. D. J. 1916, v. 22, p. 215.
CORNUS, N. F.
Anon.: A short note giving information relative to the production
and collection of dogwood bark in America.—N. A. R. D. J. 1916,
y. 21, p. 1114.
COUMARINUM, N. F.
J. P.: A review of a volume by H. Simonis entitled Die
Cumarine states that the work contains 298 pages dealing with th
history, synthesis, properties, and uses of coumarin.—Chem. Week-
blad, 1916, v. 13, p. 651-652.
177
CREOSOTUM.
E’we, G. E.: The quality of beechwood creosote during the past
year has been poor, especially in odor and color. A rank odor, and
amber, brown, and pink colors were noted in samples examined.—
roc. Pennsylvania Pharm. Assoc. 1916, p. 111.
_ Clampett, G. W.: Of nine samples of creosote examined the guaia-
‘eo! content ranged from 20 to 60 per cent.—Proc. Texas Pharm.
As-oc, 1916, p. 80.
Orchard, A.: A note on the use of creosote in the treatment of
rheumatic affections—Brit. M. J. 1916, v. 1, p. 167.
_ CRESOL.
E’we, G. E.: Most of the cresol is offered as “technical” and is
not as soluble in water as that offered as “U.S. P.,” but it produces
a clear soluble compound solution of cresol of satisfactory phenol
- coefficient.—Proc. Pennsylvania Pharm. Assoc. 1916, p. 111.
_ Vanderkleed, C. E.: Only 2 of the 16 lots of cresol examined had
_ aspecifie gravity within the U. S. P. limits of 1.036-1.038, All but
one of the samples answered the requirements of 90 per cent, dis-
tilling between 195 and 205° C.—J. Am. Pharm. Assoc. 1916, v. 5,
_ —p. 538. .
_ Steenhauer, A. J.: Data. showing the relative disinfecting powers
_ of ortho-, meta-, and para-cresol and mercury oxycyanide.—Pharm.
-Weekblad, 1916, v. 53, p. 680-685.
CROCUS, N. F.
- Braune, F. R.: The author recommends storing saffron in small
_ giass-stoppered bottles, with a pledget of moist cotton fitting into
the hollow stopper. An abstract.—Merck’s Report, 1916, v. 25,
p. 189,
Anon.: A short note giving information relative to the cultivation
_ of saffron in America.—N. A. R. D. J. 1916, v. 21, p. 704.
- Pierlot: On the value of the determination of the total nitrogen
by the Kjeldahl method as means of indicating the purity of saf-
fron. It is stated that it is also desirable to determine the total am-
monium and the potassium nitrate present, since ammonium salts
and potassium nitrate are sometimes used as adulterants.—Schweiz.
_ Apoth.-Ztg. 1916, v. 54, p. 490-504; see also Ann. Falsif. 1916, v. 9,
p. 24-29; J. Soc. Chem. Ind. 1916, v. 35, p. 595.
Vicari, G.: Experiments with phosphomolybdiec acid as a re-
agent for the detection of safflower in saffron.—Répert. Pharm. 1916,
vy. 28, part 1, p. 24-25, from J. suisse pharm. Oct. 28, 1915; see also
A. Verda, p. 207.
110095°—19—12
178
Tunmann, O.: A description of a microchemical method for dis-
tinguishing between crocetin and the other carotinoids, especially
carotin.—Chem. Zentralbl. 1916, v. 2, p. 279, from Apoth.-Ztg. 1916,”
y. 3l, p. 237-238. :
Tunmann, O.: A discussion of certain phases of the adulteration
of saffron.—Chem. Zentralbl. 1916, v. 2, 282-283, from Apoth.-Ztg.
1916, v. 31, p. 230-231.
CUBEBA.
Lilly, J. K.: One lot of cubeb examined exceeded the U. 8. P.
requirements in the amount of stems which it contained.—Oil, Paint
& Drug Rep. 1916, v. 90, No. 16, p. 46.
Halberkann, J.: A note on the isolation of a pseudocubebin from
the bark of Ocetea usambarensts Engl.—Chem. Zentralbl. 1916,
vy. 2, p. 381-3382.
CYPRIPEDIUM, N. F.
Hommell, P. E.: An enumeration of the varieties of cypripedium
employed in medicine and a discussion of their therapeutic uses.—
Proc. New Jersey Pharm. Assoc. 1916, p. 40-43.
Lilly, J. K.: One lot of lady slipper examined consisted of some —
unknown root mixed with serpentaria.—Oil, Paint & Drug Rep. —
1916, -v. 90, No. 16, p. 46.
DELPHINIUM, N. F.
Anon.: A short note giving information relative to the cultiva-
tion of larkspur in America.—N. A. R. D. J. 1916, v. 21, p. 702.
Roberts, J. G.: One lot of larkspur seed containing numerous
small stones yielded 8.3 per cent of ash. A detemeaaae was made
on clean, hand-picked seed, and 5.76 per cent of ash was obtained.—
Proc. Pennsylvania Pharm. Assoc. 1916, p. 114.
DIACETYLMORPHINA.
Melver and Johnson: Heroin came into use by the medical pro-
fession about 1898 and was thought to be a safe and efficient drug
for use in place of morphine. Some time later it was noticed that
patients had become addicted to the use of this drug, but not to the
same extent as was the case with morphine.—J. Am. M. Assoc.
1916, v. 66, p. 478 .
Doran, James M.: A description of a rapid method for the sepa-
ration of heroin and morphine in the quantitative determination of
these substances.—J. Am. Pharm. Assoc. 1916, v. 5, p. 163-165.
DIASTASUM.
Takamine, J.: U. S. Patent No. 1,192,584. A method for the
production of a diastatic product by means of the fungus Aspergillus
oryz@ is described.—Chem. Abstr. 1916, v. 10, p. 2316,
179
Pollak, I.: A review dealing with diastase preparations and their
pplication in practice.—Chem. Abstr. 1916, v. 10, p. 798.
Palmer, C. C.: The author has demonstrated the presence of
jastase in the saliva of the ox.—Am. J. Physiol. 1916, v. 41, p.
83-491.
Rakuzin, M. A., et al.: In a discussion of the limits of sensitive-
“Chem. Soe. 1915, v. 47, p. 2051-2056.
Grimbert, L.: A report of an investigation of the assay of diastase
_according tc the method of the French pharmacopeia.—J. pharm.
et chim. 1916, v. 13, p. 5-16; see also Ann. Falsif. 1916, v. 9, p. 90-95.
% DIGITALIS.
_ Sharp, Gordon: A historical note on the introduction of digitalis
“as a therapeutic agent—Pharm. J. 1916, v. 96, p. 547.
Kiliani, H.: Researches on digitalis glucosides and their decom-
position products.—J. Soc. Chem. Ind. 1916, v. 35, p. 615 from Ber.
deutsch chem. Gesellsch. 1916, v. 49, p. 701.
_ Berry, E.: A report of an investigation of the active principles
‘of Digitalis purpurca—Pharm. J. 1916, v. 41, p. 788.
_ Puckner, W. A.: A report on digitalysatum. A review of the
exaggerated claims made in regard to it; in the main indirectly.—
/J. Am. M. Assoc. 1916, v. 66, p. 135-136.
_ Straub, W.: Researches on the chemical constitution and pharma-
ecological action of digitalis drugs.—J. Chem. Soc. Lond. 1916, v.
110, p. 617 from Biochem. Ztschr. 1916, v. 25, p, 182-134.
_ Hercod, E.: A retrospective study of the physiological stand-
-ardization of heart tonics—Chem. & Drug. 1916, v. 88, p. 147-148
and 803.
Hamner, J. W.: A report of analytical data obtained in the physi-
ological testing of digitotal and other digitalis preparations by
the Focke and Gottlieb methods.—Svensk farm. Tidskr. 1916, v. 20,
“p. 273-277.
Zeigler, W. H.: A criticism of the biologic methods for the stand-
ardization of digitalis with a suggestion for a new method. The
fresh-water terrapin, or turtle, is suggested as the test animal.—J.
“Am. Pharm. Assoc. 1916, v. 5, p. 1188-1193.
~ Loewe: A polemic argument against R. Gottlieb in defense of O.
Loeb on the standardization of digitalis by the frog method with
an addendum by R. Gottlieb Miinch. med. Wehnschr. 1916, v. 63,
“p. 424-425 through Chem. Abstr. 1916, v. 10, p. 1690.
180
Roth, George B.: Digitalis standardization. The physiologica)
evaluation of fat-free digitalis and commercial digitalin—Bull. Hyg.
Lab. 1916, No. 102, p. 5-88.
owhitree, a; G., and Macht, D. T.: Data showing the relative
physiological activity of Cee English, and American as oon —
J. Am. M. Assoc. 1916, v. 66, p. 870-871.
Newcomb, E. L.: Bata showi ing the potency of the digitalis grown
at the University of Minnesota in 1915.—Proc. oe Pharm.
Assoc. 1916, p. 153-155.
Wasicky, R.: Biological tests of Digitalis ambiguia Murr. by the
one-hour method of Hale showed it to be as valuable as the official
digitalis——Chem. Zentralbl. 1916, v. 87, pt. 1, p. 1264. .
Soe The digitoxin content of two ee of digitalis leaves
assayed was above standard.—Proc. Pennsylvania Pharm. Assoe.
1916, p. 119.
Clampett, G. W.: Of eight samples of digitalis leaves examined,
the digitoxin content ranged from 0.088 to 0.30 per cent.—Proe.
Texas Pharm. Assoc. 1916, p. 80.
‘Vanderkleed, C. E.: The two samples of digitalis leaves examined
contained 0.293 and 0.365 per cent of digitoxin, the standard being —
0.25 per cent.—J. Am. Pharm. Assoc. 1916, v. 5, p. 538.
“Patch, E. L.: The ash content of the four samples of digitaiad |
leaves Sees was from 8 to 9.5 per cent—J. Am. Pharm. Assoe.
1916, v. 5, p. 538. .
Halsey, J. T.: A discussion of the dosage of digitalis and its tine-
ture.—Southern M. J. 1916, v. 9, p. 579-580.
Schapiro, F.: The action of digitalis alone, and in combination ~
with ephinephrine and thyroid upon the heart of Rana esculenta.—
3iochem. Ztschr. 1916, v. 73, p. 1-14; see also Chem. Abstr. 1916, vy.
10, p. 1680.
Schulz, Hugo: A report of some new investigations rela to the
influence of digitalis, or plants related to it botanically, upon the
color sensitiveness of the human eye.—Physiol. Abstr. 1916, v. 1,
p- 514.
Halsey, J. T.: A discussion of the clinical value of various “ digi- —
talis ” drugs and preparations.—Southern M. J. 1916, v. 9, p. 677-679. -
Haskell, Charles C., McCants, C. S., and Gardner, E. P.: Re-
searches on the rate of and absorption of various digitalis prepara-
tions from the gastro-intestinal tract—Arch. Int. Med. 1916, v. 18,
p. 285-243,
Golovinsky, J. V.: From the action of solutions of digipuratum
on the splanchnic and portal systems, the author concludes that the
increased blood pressure after the administration of digitalis is due—
to the increased cardiac activity. An abstract—J. Am. M, Assoe. ”
1916, v. 66, p. 850. ;
181
_ White and Sattler: The effect of digitalis on the normal human
electrocardiagram with especial reference to A-V conduction.—J.
Exper. M. 1916, v. 23, p. 615-632; see also Chem. Abstr. 1916, v. 10,
. 1681.
_ Stevens, Harold W.: Some electrocardiographic studies of patients
under digitalis treatment.—Boston M. & S. J. 1916, v. 174, p. 845-350.
Taylor, Seymour: Notes on the value of digitalis in the treatment
of aortic incompetence.—Lancet, 1916, v. 191, p. 96-98.
White, Paul D.: A report on cases of auricular standstill—an
unusual effect of digitalis on the heart.—Boston M. & S. J. 1916,
y. 175, p. 233-236.
| DIOSCOREA, N. F.
Anon.: A short note giving information relative to the cultivation
| of the wild yam in America.—N. A. R. D. J. 1916, v. 21, p. 1275.
DULCAMARA, N. F.
Anon.: A short note giving information relative to the produc-
_ tion and collection of bittersweet in America.—N. A. R. D. J. 1916, v.
m 21, p. 1114.
: ECHINACEA, N. F.°
Lally, J. K.: One lot of echinacea examined consisted of the roots
_ of Rudbeckia fulgida—Oil, Paint & Drug Rep. 1916, v. 90, No, 16,
ip. 46.
ELIXIRIA.
Anon.: As it is a fact that the interests of good pharmacy, as well
as the interests of the patient, require the best possible in medicine,
so it is to be hoped that in all formulas for an elixir in which a fluid
_ extract is indicated the drug itself will be employed. It is a serious
_ error that the National Formulary does not state this in just so many
words —N. A. R. D. J. 1916, v. 22, p. 1034.
_ Kimmich, E.: A report of investigations to determine the cause
for the deterioration of elixirs containing iron salts——Canadian
» Pharm. J. 1916, v. 49, p. 223.
— Cook, E. Fullerton: A number of new vehicle elixirs have been
introduced into the N. F. in order to provide for the physician a
' greater variety of flavors than were heretofore available—Drug.
Cire. 1916, v. 60, p. 542.
Frary, Guy G.: Six of the 19 samples of Elixir of Lactated Pep-
sin examined were found to be low in proteolytic power. ‘There is
no fixed standard in the U.S. P. or N. F. for this preparation, but
_ the values were computed with respect to the designation on the label,
_ viz, “40 grain,” “80 grain,” ete—Rep. South Dakota F. & D. Com.
1916, No. 16, p. 142-144,
182
ELIXIR AROMATICUM.
Anon.: Magnesium carbonate is recommended for use in clarify-
ing aromatic elixir. The product is stated to be perfectly clear on
the first filtration and not to precipitate on standing.—Midl. Drug.
1916, v. 50, p. 22.
ELIXIR CASCARAE SAGRADAE, N. F.
Anon.: The change in the title for Elixir Rhamni Purshiane, N,
F. III, is of doubtful value and a backward step in science.—N. A. —
R. D. J. 1916, v. 22, p. 1081.
ELIXIR CATHARTICUM COMPOSITUM, N. F.
Anon.: The retention of the therapeutically suggestive title for
this elixir seems queer.—N. A. R. D. J. 1916, v. 22, p. 1081.
ELIXIR CINCHONA ALKALOIDORUM, N. F.
Anon.: While the elixir of cinchona alkaloids is an elegant and
useful preparation pharmacally, it would be much more efficient
medicinally if made from cinchona bark. It is also rather weak in|
strength —N. A. R. D. J. 1916, v. 22, p. 1081.
ELIXIR DIGESTIVUM COMPOSITUM, N. F.
Anon.: The deletion of this preparation, while it will in no way
affect its extended use, seems to be a victory for the adherence of
“test tube” medication, and a defeat for the practical prescribing
physician.—N,. A. R. D. J. 1916, v. 22, p. 1082.
ELIXIR FERRI HYPOPHOSPHITIS, N. F.
Anon.: In the preparation of the elixir of iron hypophosphite,
ferric hypophosphite is now used, with the addition of potassium
citrate, the latter for the purpose of obtaining a more permanent
preparation and as an aid in dissolving the iron salt.—N, A. R. D. J.
1916, v. 22, p. 1082.
ELIXIR FERRI, QUININAS ET STRYCHNINA, N. F.
Cook, E. Fullerton: The only official elixir of iron, quinine, and
strychnine is that of the N. F., and it does not contain the ingre-
dients in the form of phosphates. The latter was purposely omitted
from both the U. S. P. and N. F. because of its instability —Drug.
Cire. 1916, v. 60, p. 542.
Stinson, Ray: Ninety-seven, or 83 per cent, of the 117 samples of —
elixir of iron, quinine, and strychnine examined were below standard,
the minimum being 24 per cent of the U. S. P. strength.—Proe.
North Dakota Pharm. Assoc. 1916, p. 112.
MARGE ct 8A Ei IER Eis Ate Dp DEL GM
F< Sue Copnenall <4
‘ae SS
.
185
ELIXIR FERRI, QUININA) ET STRYCHNIN-E PHOSPHATUM.
Diekman, George C.: It is to be regretted that the elixir of iron,
‘quinine, and strychnine phosphate has been deleted from the U.S. P.
and not taken up by the N. F. An article in such common use can
ot be relegated to the scrap heap by any revision committee. The
reason given for its omission—i. e., that a satisfactory formula for its
preparation could not be devised—is unfortunate since manufacturers
produce an elixir which is most satisfactory in all respects.—Pract.
Drug. 1916, v. 34, No. 10, p. 26.
hf
ELIXIR FORMATUM, N. F.
Anon.: The elixir of formates would be more efficient were the po-
_ tassium salt replaced with calcium carbonate.—N. A. R. D. J. 1916
Py. 22, p. 1082.
4
4
& ELIXIR GENTIANZ ET FERRI, N. F.
’
E Anon.: Detailed directions for the preparation of elixir of gentian
with tincture of chloride of iron are given—N. A. R. D. J. 1916, v.
721, p. 863.
ELIXIR GLYCEROPHOSPHATUM, N. F.
Anon.: Detailed directions for the preparation of the elixir of gly-
_cerophosphates are given and discussed—N. A. R. D. J. 1916, v. 21,
_p. 1064.
ELIXIR GLYCEROPHOSPHATUM COMPOSITUM, N. F.
Anon.: As an improvement in the formula for the preparation of
the elixir of glycerophosphates, it is suggested that glycerophos-
phoric acid might replace the lactic acid—N. A. R. D. J. 1916, \
722, p. 1259.
: ELIXIR MALTI ET FERRI, N. F.
Anon.: The elixir of malt and iron is an elegant preparation which
‘should have been retained, as its medicinal worth exceeds that of
many less important elixirs that have not been deleted—N. A. R. D.
Bd. 1916, v. 22, p. 1259.
2 ELIXIR PEPSINI, BISMUTHI ET STRYCHNINA, N. F.
; —- This elixir could well have been deleted from the N. F.
as all soluble salts of bismuth are injurious when taken internally,
and combinations of such with pepsin are unscientific and may be
-dangerous.—N. A. R. D. J. 1916, v. 22, p. 1259,
184
ELIXIR PEPSINI ET RENNINI COMPOSITUM, N. F.
Anon.: A discussion of some liquid preparations of pepsin, includ-
ing several formulas.—N. A. R. D. J. 1916, v. 21, p. 711-712; see
also p. 863-864.
Anon.: As a medical monstrosity this preparation is carta |
much worse than the compound digestive elixir of the N. F. III, yet
the latter was deleted. The amount of alcohol is entirely too great;
in fact, alcohol and pepsin are see aes) and medicinally incom-
' patible—N. A. R. D. J. 1916, v. 22, p. 125
Congdon, Leon A.: One sample of essence of pepsm examined was
rejected.—Rep. Kansas Bd. Health, 1916, p. 138.
ELIXIR PHOSPHORI, N. F.
Anon.: The present elixir contains no sugar, which is rather a
handicap, for sugar apparently increases the medicinal action of
phosphorus without being detrimental in any way.—N. A. R. D. J.
1916, v. 22, p. 1259-1260.
ELIXIR PICIS COMPOSITUM, N. F.
Anon.: In discussing the preparation of the compound elixir of
tar, it is stated that the morphine is of little value in the elixir and
it is hoped that the new edition of the N. F. will omit it—N. A. R.-
D..J. 1916; v. 21; p. 659:
ELIXIR POTASSII BROMIDI, N. F.
Todd, A. R.: Of three samples of elixir of potassium bromide ex-
amined, one was rejected.—Bull. Michigan D. & F. Dept. 1916, No.
244-947, p. 20. |
ELIXIR SODII SALICYLATIS COMPOSITUM, N. F.
Anon.: A formula for the preparation of the compound elixir of
sodium salicylate in which the drugs instead of fluid Brie are
employed is given and discussed.—N. A, R. D. J. 1916, vy. 22, p. 166,
ELIXIR TERPINI HYDRATIS, N. F.
Anon.: A discussion of a revised formula for the preparation of
the elixir of terpin hydrate.—N. A. R. D. J. 1916, v. 21, p. 1021.
ELIXIR TERPINI HYDRATIS CUM CODEINA, N. F.
Anon.: The usual dose of terpin hydrate is 5 grains, any less is
of little value. Therefore, the only effect produced by the elixir,
which contains 1 grain of terpin hydrate to the drachm, is due to_
the sedative action of the codeine sulphate-—J. Am. M. Assoc. 1
v. 66, p. 1199.
185
ELIXIR TERPINI HYDRATIS ET DIACETYLMORPHINA, N. F.
Congdon, Leon A.: The sample of elixir of terpin hydrate and
diacetylmorphine examined was rejected for being below standard,—
Bull. Kansas Bd. Health, 1916, v. 12, p. 7.
ELIXIR VIBURNI OPULI COMPOSITUM, N. F.
Anon.: A discussion of two formulas for the preparation of the
compound elixir of cramp bark.—N. A. R. D. J. 1916, v. 21, p. 1222.
Anon.: Notes on the preparation of the compound aes of cramp
bark, with a formula for preparing the same from crude drugs in-
stead of fluid extracts—N. A. R. D. J. 1916, v. 23, p. 12.
EMETINZ HYDROCHLORIDUM.
Anon.: Emetine hydrochloride was added to the U. S. P. IX in
view of the excitement created by the dental profession over its use
in pyorrhea. The excitement has already died down and the de-
mand is falling off, as it has not done all that was claimed for it.—
Drug Lopies, 1916; No. 9, p. 7.
Kolmer, John A., and Smith, Allen J.: A report of researches to
determine the bactericidal and protozoacidal activity of emetine
hydrochloride iz vitro and im vivo—ZJ. Infec. Dis. 1916, v. 18, p.
247-276.
Pellini, E. J., and Wallace, G. B.: A report of researches on the
pharmacology of emetine.—Am. J. M. Sc. 1916, v. 152, p. 325.
Levy and Rowntree: The toxicity of various commercial prepara-
tions of emetine hydrochloride.—Arch. Int. Med. 1916, v. 17, p.
490-433; see also Chem. Abstr. 1916, v. 10, p. 1676.
Kilgore, A. R.: A report of cases of peripheral neuritis following
the administration of emetine in the treatment of ameebic dysen-
tery —Boston M. & 8. J. 1916, v. 175, p. 380-882.
Bates, John Pelham: A discussion of the treatment of amcebic
dysentery by the use of emetine—J. Am. M. Assoc. 1916, v. 67, p.
845-347,
Editorial: A review of the use of emetine in the treatment of
dysentry.—Prescriber, 1916, v. 10, p. 197.
Allan, J.: A report on the treatment of soldiers; who have re-
turned from the front with dysenteric symptoms, by the use of
H _ emetine hydrochloride.—Prescriber, 1916, v. 10, p. 105.
Lowell, Ralph P., and Cobb, Stephen A.: A comparative study of
the value of emetine hydrochloride and mercury succinimid in the
treatment of pyorrhea alveolaris.—Dental Cosmos, 1916, v. 58. p.
508-510. -
Ruoff, K. H.: A report of the results obtained in 78 cases of
pyorrhea treated with emetine hydrochloride. All of the cases
186
showed endamebz again in periods varying from two weeks to four
months.—Am. J. Pharm. 1916, v. 88, p. 164.
Editorial: A discussion of the value of emetine in the treatment —
of psoriasis.—Prescriber, 1916, v. 10, p. 201.
Beekman, Marcus: An experimental study of the effect of emetin-
ized blood on the typhoid bacillus.—Med. Rec. 1916, v. 89, p. 284; see
aiso Chem. Abstr. 1916, v. 10, p. 1380.
Dale, H. H.: A note on the use of the double iodide of emetine and
poe des in the treatment of carriers of amcebic dysentery.—Lancet,
1916, v. 191, p. 183-184.
Dobell. Clifford: A report on the relative effectiveness of a
hydroc hloride and emetine bismuthous iodide in the elimination of
Endomocha hystolytica—Brit. M. J. 1916, v. 2, p. 612-616.
Low, George C., and Dobell, C.: Records are presented showing |
the superiority of emetine bismuthous iodide over emetine hydro-
chloride in the treatment of acute amoebiasis and carriers.—Lancet,
1916, v. 2, p. 319-820.
EMPLASTRA.
Dietrich: The use of plasters containing free resins is condemned
since they irritate the epidermis. Formulas for the preparation of
neutral plasters are given. An abstract.—J. pharm, et chim, 1916, v.
13, p. 54.
EMPLASTRUM BELLADONNZA.
Scoville, Wilbur L.: No formula for the preparation of bella-
donna plaster is given in the U. S. P. TX because it can only be pre-
pared on a commercial basis, special machinery and skill being neces-
sary.—Bull. Pharm. 1916, v. 30, p. 363.
EMULSA.
Roon, Leo: A brief résumé of the developments in the theory of
emulsification which might be of practical application and of general
interest to the pharmacist. A bibliography is appended—J. Am.
Pharm. Assoc. 1916, v. 5, p. 496-505.
Barcroft, Wilder D.: A presentation of a theory of emulsification.
ys. Chem. 1916, v. 20, p. 1-381.
Fischer, M. H., and Hooker, M. O.: A study of emulsions of cot-
tonseed oil in water.—Chem. Zentralbl. 1916, v. 2, p. 47.
De G. Peacock, Josiah C. and Bertha L.: A discussion of vari-
ous methods for the preparation of emulsions of silver iodide.—
ao . » SCY re 16 « , j v4] . € 9 . *
Proc. Pennsylvania Pharm. Assoc, 1916, p. 231-243; see also J. Am.
Pharm. Assoc. 1916, v. 5, p. 727-784.
187
EMULSUM OLEI MORRHUZ.
Kramer, S. P.: U. S. Patent No. 1,207,936. A method for emul-
sifying cod liver oil by means of a soluble silicate—Chem. Abstr.
1917, v. 11, p. 276.
EMULSUM PHOSPHATICUM, N. F.
_ Anon.: The dropping of phosphatic emulsion is certainly a bad
-mark against the revision committee. Pharmacists should continue
their active propaganda in behalf of it, for physicians like it and
| get good results from its use.—N. A. R. D. J. 1916, v. 22, p. 1305.
_ ERGOTA.
Roberts, J. G.: Of two lots of ergot examined, only one was of
epee Pa activity. — Proc. Pennsylvania Pharm.
Kine, G o LE: Of two samples of ergot assayed, the cornutine con-
tent of one was above standard and one was below.—Proc. Penn-
‘sylvania Pharm. Assoc. 1916, p. 119.
_ Vanderkleed, C. E.: The cornutine content of the six lots of ergot
~ examined was from 0.115 to 0.380 per cent.—J. Am. Pharm. Assoc.
71916, v. 5, p. 538.
EUONYMUS, N. F.
Anon.: A short note giving information relative to the production
- collection of wahoo er in America—N,. A. R. D. J. 1916, \
1, p. 1114.
= es
EUPATORIUM, N. F.
Anon.: Information relative to the cultivation and harvesting of
boneset is given.—N. A. R. D. J. 1916, v. 23, p. 504-505,
EXTRACTA.
Diekman, George C.: The number of extracts in the Pharma-
copeia has been reduced from 28 to 25. This number might have
Breen still further reduced without materially interfering with the
value of the work. It is regretted that so much prominence is given
to powdered extracts, since they have been deprived of all volatile
matter and therefore do not represent the constituents of the drug
in all cases.—Pract. Drug. 1916, v. 34, No. 10, p. 24.
_ <Anon.: A criticism of the U. S. P. directions for the preparation
of extracts states that common sense would seem to indicate that
when a drug contains a volatile oil such a drug is not fit to be
represented in either the U. S. P. or N. F. by a powdered extract.—
ON. A. R. D. J. 1916, v. 23, p. 70.
5
SERPS POR PG Op OO PR i Os er a
~S
Pt ip
188
Maines, E. L.: It is suggested that the next revision committee
consider the advisability of adopting a uniform and definite rela-
tion of drug to extract for every commercial crude drug and that
this list of standards be included in the text of the next Pharma-_
copeia for both solid and powdered extracts—J. Am. Pharm.
Assoc. 1916, v. 5, p. 1067.
Anon.: A review of the U. S. P. IX states that the admission of
the extracts of aconite, hydrastis, and viburnum prunifolium is un-
fortunate, since these preparations are superfluous——J. Am. M.—
Assoc. 1916, v. 67, p. 764.
Lyubimenko, V.: A theory for the explanation of the change in
color of green extracts. The color change is stated to be due to a dis-
turbance of the equilibrium existing between the enzymes present,
which results in the destruction of the green pigments. An ab-—
stract—Pharm. J. 1916, v. 97, p. 505.
Heiduschka, A., and Schmid, J.: Data obtained from the estima-
tion of sugar in some extracts and tinctures are presented. An ab-
stract—Pharm. Weekblad, 1916, v. 53, p. 1334.
EXTRACTUM CARNIS, N. F.
Lebbin: A paper dealing with the manufacture of beef extracts
and with the chemical standards to which they should conform. An
abstract.—Drug. Cire. 1916, v. 60, p. 407.
Vanderkleed, C. E., and E’we, G. E.: Directions for the applica-
tion of the Wilfarth modification of the Kjeldahl] method for the
determination of nitrogen in the assay for protein in beef extract
and wine of beef and iron.—J. Am. Pharm. Assoc. 1916, v. 5, p. 716.
Smith, W. B.: A description of a method for the estimation of
sugar in meat products, particularly extracts.—J. Ind. & Eng. Chem.
1916, v. 8, p. 1024-1027.
Patch, E. L.: Samples of extract of beef examined showed a varia-
tion in protein content from 36.56 to 55 per cent.—J. Am. Pharm.
Assoc. 1916, v. 5, p. 536.
EXTRACTUM VIBURNI PRUNIFOLII.
Anon.: The appearance of the extract of viburnum prunifolium in
the U. S. P. TX will give a shock to the council of medicine and —
pharmacy of the A. M. A., who have condemned it as worthless.—
Drug Topics, 1916, No. 9, p. 7.
FERRI PHOSPHAS SOLUBILIS.
Holmes, Harry M., and Rindfusz, R. E.: Researches on the prep-.
aration and properties of the colloidal arsenates and php of
iron.—J. Am, Chem, Soc. 1916, v. 388, p. 1970-1982,
189
FERRI SULPHAS EXSICCATUS,
Riv andericivea, C. E.: The 2FeSO,.8H,O content of 15 lots of dried
ferrous sulphate examined ranged between 80 and 104.3 per cent.—
J. Am. Pharm. Assoc. 1916, v. 5, p. 589.
FERRUM.
Mayer, J. L.: A description of a colorimetric method for the es-
timation of iron in pharmaceutical preparations, especially in wine
of beef and iron.—Am. Drug. 1916, v. 60, p. 169.
van Eck, P. N.: A criticism of the Codex Alimentarius method for
the colorimetric determination of iron as thiocyanate—Pharm.
Weekblad, 1916, v. 53, p. 1570-1572.
Brandt, L.: A discussion of the standardization with iron oxide as
the basis for volumetric iron determinations in hydrochloric acid
solutions.—Chem.-Ztg. 1916, v. 40, p. 605-607, 631-633.
Roberts, J. G.: The free iron (uncombined) in 25 samples of iron
filings ranged from 22.9 per cent to 95.34 per cent.—Proc. Pennsyl-
vania Pharm. Assoc. 1916, p. 113.
Montgomery, Douglas W.: A note on the alliaceous odor produced
by iron cacodylate. The disagreeable odor of the drug may become
apparent in the breath even when given hypodermically.—J. Am. M.
Assoc. 1916, v. 66, p. 491-492.
FERRUM REDUCTUM.
Stinson, Ray: Of 59 samples of reduced iron examined, 82 were
below standard.—Proc. North Dakota Pharm. Assoc, 1916, p. 112.
Swift, E. G.: One sample of “iron by hydrogen” examined con-
tained only 80 per cent of iron—Oil, Paint & Drug Rep. 1916, v. 90,
No. 16, p. 46.
FLUIDEXTRACTA.
Diekman, George C.: The number of fluid extracts in the Pharma-
copeeia has been reduced from 85 to 49. Good judgment is shown in
the matter of deletions, the relatively unimportant members of this
group having been dropped.—Pract. Drug. 1916, v. 34, No. 10, p. 24.
Anon.: In a review of the new U.S. P., it is stated that those in-
terested in the promotion of rational therapy will regret the inclusion
of a number of fluid extracts of violently toxic drugs, such as aconite
and gelsemium (dose 4 minim each), belladonna root, digitalis, nux
vomica and ipecac (dose 1 minim each), and lobelia (dose 24 minims),
The more diluted forms, the tinctures, of these drugs are preferable.
The inclusion of such fiuid extracts in the Pharmacopeeia is playing
into the hands of certain pharmaceutical manufacturers, who recom-
mend that tinctures be prepared from fluid extracts—an unscientific
procedure.—J. Am. M. Assoc. 1916, v. 67, p. 764.
190
Anon.: Ina review of the preparations of the N. F. LV, it is stated
that, from every practical and economical viewpoint it would be —
of inestimable value to the art of pharmacy if fluid extracts as a class
were dropped as official preparations, and a new class of preparations ©
to be called “50 per cent tinctures ” be substituted in their place.—
Ne gAc DS AOLG, woes. Te:
Anon.: It is most sincerely hoped that before another revision of —
the U. S. P. and N. F. takes place (only three and one-half years
hence) the pharmacists of the country will have become enlightened —
to such a degree as to demand the dismissal of the fluid extracts from —
their standards and their replacement with practical preparations.—
Nu A. R. D. J. 1916, v. 23, p. 520.
Francis, J. M.: If properly protected from light, contact with air, —
and the less of alcohol, a normal activity may be expected for the
fluid extracts of belladonna leaves or root, ipecac, nux vomica, and
cpium for a period of at least three years and in many cases for
five or six years.—Am. Food J. 1916, v. 11, p. 408.
Congdon, Leon A.: Eight samples of fluid extracts examined were
rejected for being in a deteriorated condition—Rep. Kansas Bd.
Tealth, 1916, p. 133.
FLUIDEXTRACTUM ACONITI.
Francis, J. M.: From experiments, it is concluded that the fluid
extract of aconite retains at least 80 per cent of its activity for 12
months.—Am. Food J. 1916, v. 11, p. 408.
FLUIDEXTRACTUM CINCHONA.
Anon.: Pharmacists should bear in mind that the new formula —
fer the fluid extract of cinchona contains diluted hydrochloric acid,
and that the preparation is therefore incompatible with carbonates
and bicarbonates. Physicians should be cautioned accordingly, as
they very frequently prescribe mixtures of this kind.—N. A. R. D. J.
1916, v. 23, p. 510.
FLUIDEXTRACTUM COCA.
Caspari, Charles, jr.: The deterioration of all galenical prepara-
tions of coca leaves is beyond control in the light of our present
knowledge concerning the chemistry of the latter—Am. Food J.
1916, v. 11, p. 407.
FLUIDEXTRACTUM DIGITALIS.
Francis, J. M.: Samples of the fluid extract of digitalis were seen
y~
by the author which tested only 50 to 75 per cent of their normal
activity after eight months. Other samples were 100 per cent active
after three years.—Am. Food J. 1916, v. 11, p. 409.
191
FLUIDEXTRACTUM ERGOT.
Francis, J. M.: Fluid extract of ergot may show only 50 per cent
of its normal activity in six months. In some samples examined the
activity was 100 per cent after five years. Asa rule the preparation
open to suspicion after 18 months.—Am. Food J. 1916, v. 11, p. 409.
FLUIDEXTRACTUM HYDRASTIS.
Blomberg, J., jr.: A presentation of analytical data obtained in
the evaluation of fluid extract of hydrastis prepared according to
he method of the Ph. Ndl. IV, the supplement to the Ph. Ndl., the
two methods of van der Haar, the method of the Ph. Germ. V,
and the method of von Ledden-Hiilsebosch.—Pharm. Weekblad, 1916,
“y. 53, p. 470-480.
van der Harr, A. W.: A note on the quantitative determination of
hydrastine in fluid extract of hydrastis by Rusting’s tragacanth meth-
od.—Pharm. Weekblad, 1916, v. 53, p. 1452-1454.
FLUIDEXTRACTUM IPECACUANH2.
Scoville, Wilbur L.: By some curious twist ipecac, U. S. P. IX,
is required to yield not less than 1.75 per cent of ether-soluble alka-
loids, while the fluid extract must yield not less than 1.8 per cent
nor more than 2.2 per cent. The fluid extract thus represents about
113 per cent of the drug.—Bull. Pharm. 1916, v. 30, p. 363.
FLUIDEXTRACTUM NUCIS VOMIC:.
McGill, A.: Of 19 samples of liquid extract of nux vomica ex-
amined, 12 were below the standard of the Ph. Brit. of 1914.—Bull.
Lab. Inl. Rev. Dept. Canada, 1916, No. 342, p. 3.
FLUIDEXTRACTUM SABAL.
Griebel, C.: Data obtained in the analysis of the fluid extract of
saw palmetto show that it contains ether-soluble fats, sodium chlo-
ride, esters of the fatty acids, chiefly of caprolic acid, fatty acids,
invert sugar, and mannose.—Chem. Zentralbl. 1916, v. 2, p. 419, from
Apoth.-Ztg. 1916, v. 31, p. 306.
FLUIDEXTRACTUM SENEG.
Mueller, Bertha: A deseription of an improved method for the
preparation of the fluid extract of senega—Am. J. Pharm. 1916,
y. 88, p. 241-243.
FLUIDEXTRACTUM VIBURNI OPULI, N. F.
Warren, L. E.: Analytical data showing the number of grams of
solids per cubic centimeter of the fluid extract of viburnum opulus.—
Rep. Chem. Lab. Am. M. Assoc. 1916, v. 9, p. 93-94.
192
FLUIDEXTRACTUM ZINGIBERIS.
Tice, William G.: Of seven samples of fluid extract of ginger ex-
amined, four were below standard.—Rep. New Jersey Dept. Health
1916, p. 72. .
FRAXINUS, N. F.
Anon.: A short note giving information relative to the produc-
tion and collection of white-ash bark in America.—N. A. R. D, J.
1916,..V2' 21,5 p. 1114.
GAMBIR.
Holmes, FE. M.: The name, Ouvreuparia Gambir (Hunter), Baillon
is another instance of the useless alteration of names caused by the
wretched application of the law of priority—Pharm. J. 1916, v. 97,
p. 485.
E’we, G. E.: One lot of gambir examined contained 64 per cent
of alcohol-soluble matter instead of the 70 per cent required.—Proe.
Pennsylvania Pharm. Assoc. 1916, p. 112.
GELATINUM.
Powell, J. R.: An address on the chemical control of gelatin”
manufacturers.—J. Ind, & Eng. Chem. 1916, v. 8, p. 982-933.
Frerichs, G.: A criticism of the Ph. Germ. method of testing
gelatin for sulphur dioxide. A more reliable method is described.—
Chem. Zentralbl. 1916, v. 87, part 2, p. 283 from Apoth-Ztg. 1916,
y. 31, p. 223. |
Trunkel, Hans: Directions for the preparation of gelatin suitable
for injections—Pharm. Ztg. 1916, v. 61, p. 65 through Chem.
Abstr. 1916, v. 10, p. 1076. .
Wells, Albert H.: A report of investigations to determine the pos-
sibilities of using gulaman dagat as a substitute for gelatin in food
and culture media.—Philippine J. Se. 1916, v, 11, see. a, p. 267-271.
Anon.: The use of animal gelatin as a food. Gelatin contains ap-
proximately the same amount of nitrogen as the more typical pro-
teins, and yields most of the amino acids characteristic of this group
of nutrients; but it does not contain the tyrosin, eystin, or tryptophan
groups, all of which are now believed to be indispensable nitrog-
enous nutrient units for the body. For this reason when gelatin
alone is supplied as the nitrogenous portion of the ration, nutritive
failure ensues.—J. Am. M. Assoc. 1916, v. 66, p. 1880-1881.
GELSEMIUM.
Vanderkleed, C, E.: The alkaloidal content of the four samples of
gelsemium examined ranged from 0.503 to 0.849 per cent.—J. Am,
Pharm. Assoc. 1916, v. 5, p. 538.
193
GENTIANA.
Anon.: A short note giving information relative to the cultiva-
jon of gentian in America.—N. A. R, D. J. 1916, v. 21, p. 702.
Tunmann, O.: The michrochemistry of gentisin and the yellow
oloring matter of /rasera carolinensis —J. Chem. Soc, Lond. 1916,
. 110, p. 874 from Apoth.-Ztg. 1916, v. 31, p, 181-182.
GERANIUM, N. F.
_Anon.: Information relative to the cultivation and harvesting of
feranium is given.—N. A. R. D. J. 1916, v. 22, p. 674-675.
GLANDULA SUPRARENALES SICCA.
~ Ogata, A.: The color reaction which takes place when a dichro-
mate is added to a solution of adrenalin is due to the reducing
properties of the two ortho hydroxyl groups. The brown precipi-
ate formed is chromium dioxide—J. Pharm. Soc. Japan, 1916,
Wo. 411, p. 387; see also Chem. Abstr. 1916,-v. 10, p. 2386.
_ Luchsch, F.: A report of the effects of suprarenal feeding in small
‘Mammals, such as rats and mice.—Physiol. Abstr. 1916, v. 1, p. 313.
GLANDULAZ THYROID SICCZE.
_ Griebel, C.: A description of a method for the detection of ex-
‘tract of bladderwrack when mixed with powdered thyroid glands.
An abstract—Pharm. Weekblad, 1916, v. 53, p. 1363.
_ Bradley, James: An article discussing the use of thyroid extract
in the treatment of malignant uveitis—J. Am. M. Assoc. 1916,
'y. 67, p. 412-413.
GLUCOSUM.
| Anon.: It is good that we now have a U.S. P. standard for this
widely used, but much abused, drug.—Drug Topics, 1916, No. 9, p. 7.
_ Wesener, J. A., and Teller, G. L.: A report of investigations on
‘the chemical composition of commercial glucose and on its digesti-
bility —J. Ind. & Eng. Chem. 1916, v. 8, p. 1009-1020,
_ Jackson, Richard F.: Information concerning the saccharimetric
‘normal weight and the specific rotation of d-glucose is given.—J.
Washington Acad. Sci. 1916, v. 6, p. 530-531.
van der Linden, T.: A review of the literature on the decompo-
‘sition products of glucose with additional data presented by the
author.—Chem. Abstr. 1916, v. 10, p. 1604.
~ Powell, C. W. R.: A study of the action of alkalies on dextrose
‘and levulose—Chem. Abstr. 1916, v. 10, p. 172, from J. Chem. Soe.
7915, v. 107, p. 1335-1346,
% 110095°—19 —13
194
GLYCERINUM.
Moore, G. A.: Notes on the extraction of glycerin from the waste
lyes obtained in the manufacture of soap.—Am. Perf. 1916, y. 11,
262-263.
Wrisley, G. H.: Comments on the Krebitz process of soap making
and glycerol recovery.—J. Ind. & Eng. Chem. 1916, v. 8, p. 733-743;
see also Chem. Abstr. 1916, v. 10, p. 2411.
Anon.: General enake on ote ioek including a table showing
the effect of the water content on the specific gravity. Tests for
determining the purity of glyeerin are also given.—Perf. & Ess. Oil
Rec. 1916, v. 7, p. 226-228.
Neuberg, Carl and Mandel, J. A.: A description of a simple method
for the detection of small quantities of glycerin. Likewise alcohols
and acids of the carbohydrate series. An abstract.—Chem. Zentralbl
1916, v. 87, part 1, p. 439-440.
Forman, Leroy: A description of a method for the quantitative
determination of glycerin in tablets and confections. The data
obtained in the analyses of a number of samples of these products’
are also given.—Pract. Drug. 1916, v. 34, No. 2, p. 37. 7
Scoville, Wilbur L.: Sunlight will decompose glycerin, formin
aldehydes and other odorous substances. The decomposition is more
rapid when glycerin is diluted with water.—Bull. Pharm. 1916, v. 30,
p. 78.
Frary, Guy G.: All of the 29 samples of glycerin examined were
passed. Five samples gave a brown color with H,SO,—Rep. South
Dakota F. & D. Com. 1916, No. 16, p. 142.
Anon.: Formulas for a number of elycerin substitutes are given.—
Chem. & Drug. 1916, v. 88, p. 569 and 990.
E’we, G. E.: A sibeciitte offered for glycerin consisted of a
diluted glycerin thickened with a little gum and sugar and con-
tained a little aleohol—Proc. Pennsylvania Pharm. Assoc. 1916, p._
112.
Langer, Alfons: Notes on the composition of various substitutes”
for glycerin.—Chem. Zentralbl. 1916, v. 87, part 2, p. 419 from Apoth.—
Zte. 1916, v. 31, p. 314-315, 342; see aie as Stephan, Chem. Zentralbl.
1916, v. 87, part 2, p. 514-515.
Lewinsohn, K.: Attention is directed to two cases in pharma-_
ceutical practice in which perkaglycerol, prepared by Neuberg as a_
substitute for glycerol, was found inadequate.—Chem. Zentralbl. 1916,
. 87, part 2, p. 159 Sa Chem. Abstr. 1916, v. 11, p. 1880.
Bailes and Schaumann: A report of iny estigations to determine —
to what extent “perkaglycerol” and other glycerin substitutes may
195
be used to replace glycerin in pharmaceutical practice.—Chem.
| Zentralbl. 1916, y. 87, part 2, p. 684.
_ Bonnet, M.: Clinical notes on the value of glycerin as dressing
for boils. An abstract.—Pharm. J. 1916, v. 97, p. 7.
GLYCERITUM BISMUTHI, N. F.
Anon: The glycerite of bismuth could well have been omitted from
the new N. F., as soluble bismuth salts and compounds are inferior
medicaments for internal use; many physicians class them as dis-
tinctly injurious.—N. A. R. D. J. 1916, v. 23, p. 112.
GLYCERITUM PEPSINI, N. F.
Anon.: A greater pepsin content would improve the medicinal
action of this preparation.—N. A. R. D. J. 1916, v. 23, p. 112.
GLYCYRRHIZA.
Parry, Ernest J.: The advisability of describing Spanish licorice
as “also known as Italian, Levant, Persian, Turkish, or Arabian
licorice” is questioned in view of the known differences existing be-
tween these commercial varieties—Chem. & Drug. 1916, v. 88,
No. 1915, p. 40.
Anon.: A short note giving information relative to the cultivation
of licorice in America.—N. A. R. D. J. 1916, v. 21, p. 702.
Anon.: The amount of licorice root brought into the United States
dropped from 100,100,000 pounds in 1914 to 47,800,000 pounds in
1915.—Com. Rep. 1916, No. 14, p. 243. .
Anon.: According to the invoice certified at the American consu-
late, 8,899,520 pounds of licorice root were shipped from Russia to
the United States during the year 1915.—Com. Rep. 1916, No. 59,
p. 988.
Houseman, Perey A.: The constituents of licorice root, their isola-
tion and properties.—Am. J. Pharm. 1916, v. 88, p. 97-105; see also
Chem. Abstr. 1916, v. 10, p. 1252.
Linz, A.: A report of comparative investigations of 27 suggested
methods for the determination of glycyrrhizin in licorice and in
licorice products.—Chem. Zentralbl. 1916, v. 2, p. 202, from Arch.
Pharm. 1916, v. 254, p. 134.
GOSSYPIIT CORTEX, N. F.
Anon.: A short note giving information relative to the production
and collection of cotton root bark in America.—N. A. R. D. J. 1916,
vy. 21, p. 1114.
196
GOSSYPIUM PURIFICATUM.
Gerrard, A. W.: A comprehensive paper describing the prepara-"—
tion of absorbent cotton.—Pharm. J. 1916, v. 96, p. 573-574. ‘
Lahache: A discussion on the evaluation of cotton and other ma-
terials used in the preparation of surgical dressings.—Répert. Pharm. —
1916, v. 28, part 1, p. 4-11.
McCutcheon, Alexander: Sphagnum moss as a substitute for cot-
ton. A detailed account of the harvesting of sphagnum moss and
its preparation for use as a surgical dressing——Pharm. J. 1916, v, 97,
p- 587-589. .
London letter: The vast demand for surgical dressings has led to
the revival of the use of sphagnum moss, which was suggested long
ago but had fallen into disuse. This material has three great ad-
vantages over absorbent cotton—cheapness, absorbency, and the fact
that its preparation is so simple that it can be carried out entirely
by unskilled workers. The moss is much more absorbent than cot-
ton, and will take up about 12 times its weight in water.—J. Am.
M. Assoc. 1916, v. 67, p. 1105.
Anon.: Notes on continental substitutes for absorbent cotton. Lig-
nin, cellulose wadding, and bog moss are mentioned.—Pacific Pharm.
1916) ¥..95-p2 S26.
GRANATUM.
van Itallie, L.: Comments on the Ph. Ndl. method for the deter-
mination of total alkaloids in pomegranate bark.—Pharm. Week-
blad, 1916, v. 53, p. 1661.
GUAIACOL.
Clampett, G. W.: Of five samples of guaiacol examined, the
guaiacol content ranged from 40 to 90 per cent—Proec. Texas Pharm.
Assoc. 1916, p. 80.
Archetti, Andrea: Descriptions of some derivatives of guaiacol
and their methods of preparation.—Boll. chim.-farm. 1916, v. 55,
p. 649-655.
Davis, N. S.: The author recommends that liquids such as guaiacol
and oil of sandalwood be prepared for administration by mixing
them with wax and placing the mass in capsules.—J. Am. M. Assoe.
1916, v. 67, p. 1160.
GUAIACUM.
E’we, G. E.: Three of eleven lots of guaiae examined contained ex-
cessive alcohol-insoluble matter as follows: 25.2, 25.5, and 28.1 per
cent, respectively. The U. S. P. allows 15 per cent.—Proe. Penn-
sylvania Pharm. Assoc. 1916, p. 113. .
Scoville, W. L.: The 14 samples of guaiac examined yielded —
alcohol-soluble matter in quantities varying from 70.3 to 97 per
ye
cent. Four of the samples yielded Jess than 80 per cent, and 7 of
them between 80 and 90 ‘per cent—J. Am. Pharm. Assoc. 1916, v.
5, p. 539.
Swift, E. G.: One sample of guaiac resin examined was found
to be worthless, one contained 63.4 per cent of resin soluble in
alcohol, and four of the samples yielded from 80 to 91.25 per
cent of material soluble in alcohol.—Oil, Paint & Drug Rep. 1916,
v. 90, No. 16, p. 46.
Vanderkleed, C. E.: The alcohol-solubility of the samples of
guaiac examined ranged between 77.5 and 99.2 per cent, the ash
content between 0.51 and 5.70 per cent.—J. Am. Pharm. Assoc.
(1916, v. 5, p. 539.
GUARANA.
Anon.: The alkaloidal content of two samples of guarana assayed
_ was above standard.—Proc. Pennsylvania Pharm. Assoc. 1916, p. 119.
| Swift, E. G.: One lot of guarana examined assayed 4.32 per cent
| of caffeine —Oil, Paint & Drug Rep. 1916, v. 90, No. 16, p. 46.
HAMAMELIDIS CORTEX.
- Anon.: A short note giving information relative to the production
-and collection of witch-hazel bark in America.—N. A. R. D. J. 1916,
m v. 21, p. 1058. |
HEXAMETHYLENAMINA.
~ Marcussen, S.: A description of a method for the preparation of
hexamethylenamine by the pharmacist——Norges Apotek. Tidsskr.
1916, v. 24, p. 23-24.
Carles, P.: A summary of tests for the identity and purity of
- urotropin.—Répert. pharm. 1916, v. 28, part 1, p. 129-180; see also J.
_ pharm. et chim. 1916, v. 13, p. 279-280.
' Sugiura, K., and Falk, K. G.: A study of the compounds which
‘urotropin forms with bromine and iodine show that a simple method
for the evaluation of this compound may be based upon the forma-
' tion of the tetraiodide.—Biochem. Bull. 1916, v. 5, p. 17-21; see also
J. Pharmacol. & Exper. Therap. 1916, v. 8, p. 89-51.
~ Collins and Hanzlik: A colorimetric method for the estimation of
free formaldehyde and hexamethylenamine.—J. Biol. Chem. 1916,
Ly. 25, p. 231-237; see also Chem. Abstr. 1916, v. 10, p. 1988.
Erulkar, A. S.: An article discussing the use and abuse of hexa-
-mine.—Practitioner (The), 1916, v. 96, p. 405-408.
Hanzlik, Paul J.: A study of hexamethylenamine as a solvent,
| diuretic, and of its effect on the reaction of urine.—J. Lab. & Clin.
- Med. 1916, v. 1, p. 321-332; see also Ann. Rep. Therap. Res. Com.
1916, v. 5, p. 81-100.
198
Guthrie, Douglas: A note on the value of hexamethy a ir
aural suppuration and in meningitis.—Brit. M. J. 1916, v. 2, p.
455-456, |
Anon.: It has been shown that hexamethylenamine has no germi-
cidal activities, except in an acid medium. Therefore it is of spe-
cial value only in infections of the pelvis of the kidney, ureters,
bladder, and urethra when the urine is acid. It can not be expected
to exert germicidal activity in the spinal fluid, which is alkaline, and
hence is of no value in the treatment of anterior poliomyelitis.—
J. Am. M. Assoc. 1916, v. 67, p. 309.
HYDRARGYRI CHLORIDUM CORROSIVUM.
Strickland, Donald K.: Laboratory notes on the quantitative de-
termination of mercury in various pharmaceutical preparations con-
taining the metal or its compounds.—J. Ind. & Eng. Chem. 1916, v.
8, p. 256-257.
Duliére: A method for the quantitative determination of mereuric
chloride in surgical dressings which depends on the precipitation of
the chloride with potassium iodide and redissolving the precipitate —
in an excess of the reagent is described. An abstract——Drug. Circ.
1916, v. 60, p. 274.
Anon.: The volumetric determination of mercuric chloride by
means of hydrazine sulphate. A description and discussion of the
method.—Siidd. Apoth.-Ztg. 1916, v. 55, p. 413.
Linhart, G. A.: Researches on the equilibria of mercuric chloride —
with other chlorides.—J. Am. Chem. Soc. 1916, v. 38, p. 1272-1280.
Brav, Aaron: A description of the effect of the accidental installa-—
tion of a stock solution of corrosive sublimate into the conf
sack.—New York M. J. 1917, v. 106, p. 1027-1029.
Millar, A. F. W.: A report of a case of mercuric pees ide poisoning
by absorption from the vagina.—Brit. M. J. 1916, v. 2, p. 453-454.
Lewis, D. S., and Rivers, T. M.: A report bf chemical studies
in a case of bichloride poisoning.—J. H. Hosp. Bull. 1916, v. 27,
p. 193-201.
Vogel, Karl M., and Lee, O. I.: Data relative to the elimination of
mercury in bichloride poisoning is presented—Med. Rec. 1916, vy.
89, p. 58-60.
Cohen, Jacob, and Bernhard, Adolph: A report of a case of mer-
curial poisoning with recovery. The patient, a woman age 28, was
treated according to the method outlined by Lambert and Patter-
J. Am. M. Assoc. 1916, v. 66, p. 1019-1020,
Thorington, C.: A report of a case of mercuric chloride poisoning —
with recovery. The patient swallowed at 10.5 grain tablet.—Southern |
Med. J. 1916, v. 9, p. 1045,
son.
199
Tantus, Bernard: An experimental study of antidotes in mercuric
chloride poisoning.—J. Lab. & Clin. Med. 1916, v. 1, p. 879-894.
Anon.: In a reference to the use of calcium sulphide as an antidote
for mercuric chloride poisoning, it is stated that J. H. Wilins, of
Cincinnati, Ohio, was able to save the lives of animals when treat-
ment was begun as late as 48 hours after the poison had been acl-
ministered.—Canadian Pharm. J. 1916, v. 29, p. 436,
Nixon, P. I.: A note on a new method for the intravenous admin-
istration of mercuric chloride, with special reference to the preven-
tion of vein obliteration—J. Am. M. Assoc. 1916, v. 66, p. 1622.
Lambert, Robert A.: Data showing the comparative resistance of
bacteria and human tissues to certain germicidal substances, includ-
ing mercuric chloride—J. Am. M. Assoc. 1916, v. 67, p. 1300-1301.
HYDRARGYRI CHLORIDUM MITE.
Boettger, W.: A report of experiments to determine the solubility
of calomel in water. Also a description of a method for the deter-
mination of small amounts of mercury in solutions. An abstract.—
J. Soc. Chem. Ind. 1916, v. 35, p. 144.
Strickland, Donald K.: Laboratory notes on the quantitative deter-
mination of calomel in various pharmaceutical preparations.—J. Ind.
& Eng. Chem. 1916, v. 8, p. 254-256.
HYDRARGYRI IODIDUM FLAVUM.
Strickland, D. K.: A description of a method for the quantitative
determination of mercuric iodide in various pharmaceutical prepara-
tions such as tablets and pills—J. Ind. & Eng. Chem. 1916, v. 8,
p. 253.
Hartley, E. G. J.: Descriptions of certain reactions produced by
mercuric iodide—J. Chem. Soc. Lond. 1916, v. 109, part 2, p.
1302-1305.
HYDRARGYRI IODIDUM RUBRUM.
Franceschi, Giambattista: A study of the action of hydrogen sul-
phide on mercuric iodide.—Boll. chim.-farm. 1916, v. 55, p. 481-483.
HYDRARGYRI SALICYLAS.
Murray, B. L.: A description of an electrolytic method for the de-
termination of mercury in the salicylate of mercury.—J. Ind. &
Eng. Chem. 1916, v. 8, p. 258.
Grignard and Abelmann, A.: A description of a new procedure
for the simultaneous determination of carbon, hydrogen, and mer-
cury in organic compounds containing mercury.—Bull. Soc. chim.
France, 1916, v. 19 and 20, p. 25-27,
200
Zeigler, M.: A report of a case of the development of anaphylactic — |
symptoms in a syphlitic produced by the intramuscular injection of —
mercury salicylate-——Med. Rec. 1916, v. 90, p. 805-807,
HYDRARGYRUM.
Anon.: “ Mercurius Vivus” is the name under which quicksilver
is official in the homeopathic pharmacopeias.—Drug. Cire. 1916, v.
60, p. 826. 4
Langston, C. E.: How war conditions have affected the output and
price of mercury. In 1914 a flask of 75 pounds was quoted at $37.50
on the San Francisco market. In February, 1916, the same was
quoted at $295.—Pacific Pharm. 1916, v. 9, p. 259-260.
Duschak, L. H., and Spencer, S. O.: An illustrated description
of an improved mercury still.—J. Phys. Chem. 1917, v. 21, p. 311-318.
Adanti, G.: A volumetric method for the determination of mer-
cury in its salts. The method is based on the reduction of the salts
to metallic mercury by means of formic aldehyde in the presence of
potassium hydroxide.—Boll. chim.-farm. 1916, v. 55, p. 5538-554.
Minovici and Grozea, E.: A description of a method for the toxi-
cological detection of mercury in which the metal is deposited on
aluminum foil—J. pharm. et chim. 1916, v. 18, p. 358.
E’we, G. E.: Several lots of mercury examined were quite dirty—
Proc. Pennsylvania Pharm. Assoc. 1916, p. 114.
Perez, L.: Notes on the preparation of mercurial emulsions, mer-
curial pomades, oils, ete—Farm. Espan. 1916, v. 48, p. 55-56.
Schamberg, Kolmer, and Raiziss: A study of the comparative
toxicity of the various preparations of mercury. The toxicity of the
various mercurial salts was found to be directly proportionate to the
amount of mercury contained therein. The differences in the molec-
ular structure of the compounds tested was found to be of little
importance in relation to their toxicity.—J. Cutan. Dis. 1915, v. 83,
p. 819-840; see also Chem. Abstr. 1916, v. 10, p. 2119: J. Ama e
Assoc. 1916, v. 66, p. 62.
Hall, Culbertson, and Slaught: An enumeration and diseussion of
the reactions resulting from the intraspinal injections of mereury.—_
J. Am. M. Assoc. 1916, v. 66, p. 2062-2063.
Zigler, M.: A report of a case of anaphylaxsis to mercury.—Med,
Rec. 1916, v. 90, p. 805-807.
HYDRASTIS.
Sayre, L. E.: A description of a garden at Douglas, Mich. which —
yields over 500 pounds of hydrastis annually—Drug Cire. 1916, v,
60, p. GOL. .
Anon.: In an academic dissertation at the University of Amster- —
dam, J. A. van Dongen states that Lvodium cicutarium, a common —
201
yild plant in Holland, is an excellent substitute for ydrustis cana-
densis as a styptie in uteri & Drug. 1916, v.
88, No. 1875, p. 41: see also J. pharm. et ahah. 1916, v. 13, p. 256.
De Waal, J. W.: Notes on the determination of hydeestine in hy-
drastis rhizome.—Pharm. Weekblad, 1916, v. 53, p. 1055-1061.
Lilly, J. K.: Ten lots of golden seal offered consisted of xanthor-
rhiza and twin-leaf roots. Serpentaria was also offered for golden
seal—Oil, Paint & Drug Rep. 1916, v. 90, No. 16, p. 46.
Nilsson: Hydrastis canadensis is frequently adulterated with the
root of Jeffersonia diphylla, twin leaf. Methods for distinguishing
the two are given. An abstract.—Drug Cire. 1916, v. 60, p. 19.
Table showing reported variation in alkaloidal content of hydrastis.
|
| Alkaloidal principles.
Number |
Reporters. ume, References.
| Minimum. | Maximum.
| a2 | —
Ra ee oe Peer 10 | 2.15 5.59 | si arene Pharm. Assoc. 1916,
4 | _p.1
Patch, EF. L © Se 3 3.2 4.241, Ts igs Hiong: Assoc. 1916, v. 5, p. 539.
peers. FG... .. 2s. =. 13 2°51 3.45 | Proc. Pennsylvania Pharm. Assoc. 1916,
; | 5. p13.
LE oh ae Lis} Se ea ie = ate 2.7 | J. Am. Pharm. Assoc. 1916, v. 5, p. 539.
Re RE Gros ticaiio. cs, « = 4 2. 23 5.5 | Oil, Paint & Drug Rep. 1916, v. 90, No. 16,
p. 46.
Wande kiced, C. E..... 5 | 3.16 | 5.39 | | J. Am. Pharm. Assoc. 1916, v. 5, p. 539.
Wendling, H.: A report of researches to determine the action of
synthetic hydrastis preparations and of fluid extract of hydrastis
on the uterus—Zentralb]. Biochem. u. Biophys. 1915, v. 18, p. 214.
HYOSCYAMUS.
Demilly, Jean: Notes on the proper conditions for the cultivation
of Hyoscyamus niger.—Bull. se. pharmacol. 1916, v. 23, p. 330-332.
Rusby, H. H.: The present U. S. P. definition of hyoscyamus is
a great improvement over that of the preceding edition, as the
Jeaves are no longer required to be collected from the plants in their
second year of growth, but may be collected at any time so long as
they yield not less than 0.065 per cent of hyoscyamus alkaloids —
Drug. Circ. 1916, v. 60, p. 537.
Johannessen: A comparison of the methods of the Swiss, German,
and Norwegian pharmacopeias for the evaluation of hyoscyamus
and belladonna leaves. An abstract.—Pharm. Ztg. 1916, v. 61, p. 116.
Newcomb, E. L., and Haynes, M. H.: Notes concerning the mois-
ture, ash, and alkaloidal content of se bs cultivated in Min-
nesota.—Northwestern Druggist (The), 1916, v. 17, No. 3, p. 35.
Barnes, J. H.: Assays of samples of Raith muticus showed
the alkaloida] content of the drug to range from 0.827 to 1.28 per
202
cent. The alkaloid was identified as hyoscyamine. An abstract
Chem. & Drug. 1916, v. 77, p. 576.
Hughes: The author found the alkaloidal content of Hyoscyamus
muticus of Egyptian origin to vary from 0.60 to 1.5 per cent, depend-
ing on stage of growth of the plant. An abstract.——C. U. C. P.
Alumni J. 1916, v. 23, p. 232.
Vanderkleed, C. E.: Twenty lots of hyoscyamus yielded from 0.31
to 0.140 per cent of alkaloids.
p- 909.
E’we, G. E.: Of nine samples of hyoscyamus assayed, the mydri-
atic alkaloidal content of five was above standard and four below.—
Proc. Pennsylvania Pharm. Assoc. 1916, p. 119.
Patch, E. L.: Two samples of hyoscyamus examined assayed 0.084
and 0.700 per cent of alkaloid, and yielded 27 and 35.8 per cent of
ash, respectively —J. Am. Pharm. Assoc. 1916, v. 5, p. 539.
Roberts, J. G.: The alkaloidal strength of two lots of hyoscyamus ~
leaves examined was below the U. S. P. standard of 0.08 per cent.
They contained 0.066 and 0.062 per cent, respectively, of mydriatic
alkaloids, which is close to the standard of 0.065 per cent adopted for
the U. S. P. IX.—Proc. Pennsylvania Pharm. Assoc. 1916, p. 113.
H¥YPOPHYSIS SICCA.
Anon.: A list of references to recent articles on the pituitary
body.—J. Am. M. Assoc. 1916, v. 66, p. 1734-1735.
Watenave, Walter K., and Crawford, Albert C.: From investiga-—
tions, it is concluded that pituitary extracts, when prepared by cer-—
tain methods, give color reactions which suggest the presence of —
epinephrine or an epinephrine-lke compound.—Rep. Therap. Res.
Com. 1916, v. 5, p. 62-75. :
Fenger, Frederick: Researches on the composition and physiologi-
cal activity of the pituitary body.—J. Biol. Chem. 1916, v. 25, p.
417-422, :
tobertson, T. B.: A description of a method for isolating the —
growth-controlling principle (tethelin) from the anterior lobe of the
pituitary body. Also a discussion of its physical, chemical, and —
physiological properties.—J. Am. M. Assoc. 1916, v. 66, p. 1009-1011. —
Goetsch, E.: The influence of pituitary feeding on growth and
sexual development. The dried powdered pituitary extract derived
from both the anterior and posterior lobes of the gland when fed —
to young rats in excessive doses (0.1 gm. daily) caused failure to —
gain in weight, loss of appetite, increasing peristalsis, a mild enteri- —
tis, and certain nervous manifestations, such as muscular tremors —
and weakness of the hind limbs.—J. Am. M. Assoc. 1916, v. 66, p. 690. —
4
:
;
;
:
AF ee ee et ee eee eke Sy! A at
SR ery ng Fe
203
_. Anon.: A report of experiments to determine the effect of pitui-
_ tary substance on the fecundity of poultry. An abstract.—Mulford’s
Vet. Bull. 1916, v. 7, p. 92-95.
INFUSUM DIGITALIS.
Dickman, George C.: The change in the formula for the prepara-
tion of the infusion of digitalis as given in the new U. S. P. is de-
sirable, since the pharmacist will no longer be able to dispense an
old deteriorated product.—Pract. Drug. 1916, v. 34, No. 10, p. 26.
Maloy, W. J.: A discussion of the various methods for the prepa-
ration of the infusion of digitalis—Proc. Florida Pharm. Assoc.
1916, p. 15-18.
Stall, George A.: A modified U. S. P. method for preparing the
infusion of digitalis is described. The author states that a better
preparation will be obtained if the infusion jar is heated before
pouring in the boiling water.—Pract. Drug. 1916, No. 5, p. 27.
INFUSUM SENNZE COMPOSITUM.
Anon.: Detailed directions for the preparation of the infusion
of senna compound are given.—N. A. R. D. J. 1916, v. 21, p. 659.
Broeksmit, T. C. N.: The addition of 80 milligrams of thymol
to 100 grams of the infusion of senna is recommended as a preserva-
tive—Pharm. Weekblad, 1916, v. 53, p. 1600-1602.
INUNCTUM MENTHOLIS COMPOSiTUM, N. F.
Anon.: The name “ ointment” would have been far more prefer-
able and correct for this preparation. While the word “ inunction ”
is a noun, it has reference to the “ rubbing of ointment” on the body
or elsewhere, and, correctly speaking, there can be no such a thing
as a generic inunction of anything.—N. A. R. D. J. 1916, v. 23, p. 112.
IODOFORMUM.
von Bonsdorff, A.: A report of a fatal case of iodoform poisoning
after intrapleural injection—J. Am. M. Assoc. 1916, v. 67, p. 1052,
from Finska Lakaresallskapets Handlingar, 1916, v. 58, No. 7.
IODUM.
van Itallie, L., and van der Zande, J.: From the results obtained
in the estimation of the amount of iodine in Zostera marina, it is
concluded that, technically, iodine can not. be produced from sea-
weeds. Pharm. Weekblad, 1916, v. 53, p. 705-708.
Anon.: The Russian colonization department has appropriated
$60,000 for the erection of a plant at Nahodaka Bay to recover iodine
from seaweed.—Chem. & Drug. 1916, v. 88, p. 953.
204:
Forbes. E. B., et al.: Analytical data showing the iodine content —
of various foods —J. Med. Research, 1916, v. 384, p. 445-458. ee
Guichard, Marcel: A new method for the determination of the—
atomic weight of iodine. The method is based on the analysis of
T,0,.—Ann. chim. applicata. 1916, v. 6, p. 279-318. |
Bordier, H., and Roy, G.: Experimental notes on colloidal iodine —
and its properties.—Compt. rend. acad. se. 1916, v. 163, p. 567-569.
Foque, Gustav: An illustrated description of an apparatus for the
sublimation and weighing of small quantities of iodine.—Bull. soe.
chim. France, 1916, v. 19 and 20, p. 270-272.
Bigg, Edward: A description of a method for the preparation of -
“nascent” iodine for use in the treatment of tuberculosis.—Brit.
M. J. 1916, v. 2, p. 256-257.
Edgar, G., and Diggs, S. H.: Data showing the rate of diffusion
of iodine in solutions of potassium iodide.—J. Am. Chem. Soe. 1916,
v. 38, p. 253.
Smith, S. W. J.: A description of a method of exhibiting the
velocity of iodine ions in solution——Chem. Abstr. 1916, v. 10, p. 1956,
from Proc. Phys. Soc. Lond. 1916, v. 28, p. 157-161.
Rupp, E., and Lehmann, F.: A description of a new method for
the determination of iodine in organic preparations.—Chem. Abstr.
1916, v. 10, p. 1808, from Arch. Pharm. 1916, v. 253, p. 483-4385.
Krauss, Robert B.: A method for the electrolytic determination of
iodine when present in organic matter is described—J. Biol. Chem.
1916, v. 24, p, 321-325.
Mill, J. Rutherford: A discussion of the incompatibility resulting
from the prescribing of iodine and sodium salicylate in the same mix-
ture-——Pharm. J. 1916, v. 96, p. 397.
Robinson, W. J.: The author cites a case in which a physician
preseribed argyrol, potassium iodide, and iodine to be dispensed in |
the same aqueous solution. The argyrol was completely decomposed,
the silver being precipitated as the iodide.—Drug. Cire. 1916, v. 60, »
p. 337,
Davis, N. S.: Iodine may be incorporated with a wax mass and
given in capsules with as good results as when given in solution.—J.
Am. M. Assoc. 1916, v. 67, p. 1160. .
Sollmann, Torald: A report of researches to determine the effect
of iodine, iodides, and iodates on the body.—J. Pharmacol. & Exper.
Therap. 1916, v. 9, p. 269-278.
Salant, William, and Livingston, A. E.: A study of the influence
of iodine and sodium iodide on the circulation—Am. J. Physiol.
1916, v. 41, p. 234-249.
Maylard, A. E.: A note calling attention to the danger of iodine
solutions for sterilizing the skin in abdominal operations.—Brit.
M. J. 1916, v. 2, p. 75.
205
“MacConkey, A. T., and Zilva, S. S.: A presentation of experimental
data relative to the value of iodine in tetanus.—Brit. M. J. 1916
1, p. 411-413,
IPECACUANHA.
_ Xrayser: A short discourse on the derivation of the name “ ipe-
eacuanha,” and on the sources of the drug. An abstract.—Am. Drug.
1916, v. 64, p. 173.
ieucby; H. H.: Suggestions for changes in the definition of ipecac
as given in the new U.S. P. The present definition is stated to be
n combination of errors.—Drug. Cire. 1916, v. 60, p. 202.
Rusby, H. H.: The presence of stems detached from the roots, as
specified in the U. S. P. IX under ipecac, can not possibly serve any
' good purpose and is certain to encourage adulteration up to the limit.
| This adulteration is not necessarily restricted to the stems of the
/ same plant, which is the most unfortunate feature of the case—Drug.
mirc. 1916, v. 60, p. 537.
Rusby, H. H.: Ipecac must now contain not less than 1.75 instead
of 2 per cent of alkaloid. This change is not included in the table
of the introduction, comprising 13 pages, and intended to include
all such changes in the strength of drugs and preparations.——Drug.
® Circ. 1916, v. 60, p. 538.
_ Karrer, P.: Researches on the constitution of the alkaloids of
ipecac.—J. Soc. Chem. Ind. 1916, v. 35, p. 177, from Ber. deutsch.
chem. Gessellsch. 1916, v. 49, p. 2057-2079.
Lloyd, John Uri: A description of the physical and chemical
_ properties of kryptonine, a constituent of ipecac. The substance
possesses alkaloidal properties. Its composition is probably repre-
sented by the formula C,,H,,N,O,—J. Am. Pharm, Assoc. 1916, v. 5
p. 1053-1064.
Allan, William: Clinical notes on the use of “ alcresta ipecac” in
| the treatment of amcebic dysentery—aAm. J. Trop. Dis. 1916, v..3,
p. 602-606.
Table showing reported variation in alkaloidal content of ipecac.
Minimum, | Maximum.
|
Ee ———$$<—— —wcmou—“
2. 28 | | Proc. Pennsylvania Pharm. Assoc 1916,
; p. 119.
ath ©)... -..:.-..- 4 1.71 2,28 | J. Am, Pharm. Assoc. 1916, v. 5 ,p. 539.
EODELUS, J. Gin Salne onus. 12 1.78 1.97
BEOVILIC, Wee issacescs. 1 IA eee oes ©
Proc. Pennsylvania Pharm, Assoc. 1916,
p. 113.
1.67 | J. Am. Pharm. Assoc. 1916, v. 5, p. 539.
Se aire 1 0 2.68 | Oil, Paint & Drug Rep. 1916, v. 90, No. 18,
2
6
Vanderkleed, C. E....- 9| 1. 66
\
Per cent of alkaloids
Number of oS ,
Reporters. samples, | References.
| p. 46.
.13 J. Am. Pharm, Assoc. 1916, v. 5, p. 539.
206
JALAPA.
Holmes, E. M., and Passmore, F. W.: As a source of jalapin
(resin of Galen incoiible in ether), the Brazilian jalap is twice as
valuable as the Vera Cruz jalap, since it contains twice the standard
quantity of resin required by the Ph. Brit—Pharm. J. 1916, v. 41,
671.
= Tunmann, O.: A paper dealing with the sophistication of pow-
dered jalap with the seed hulls of Attalea cohune Mart. and the
results obtained in microchemical investigations—Chem. Zentralbl.
1916, v. 87, part 2, p. 268, from Apoth-Ztg. 1916, v. 31, p. 263, 267-268,
273-274. .
E’we, G. E.: Of three samples of jalap assayed, the total resin
content of one was above standard and two below.—Proc. Pennsyl-
vania Pharm. Assoc. 1916, p. 119.
Swift, E. G.: Of nine samples of jalap received in the latter half
of 1915, five yielded less than 6 per cent of total resins, three be- —
tween 6 and 7 per cent, one 7.29 per cent, and one 10.21 per cent. In
1916 the poorest sample yielded 8.5 per cent of resin and the best
11.05 per cent—Oil, Paint & Drug Rep. 1916, v. 90, No. 16, p. 46.
Vanderkleed, C. E.: One sample of jalap examined contained 7.17
per cent of resin. The standard is 7 per cent.—J. Am. a ;
Assoc, 1916, v. 5, p. 539.
JUGLANS, N. F.
Anon.: A short note giving information relative to the preduction —
and collection of butternut bark in America.—N. A. R. D. J. 1916, —
Vo 21 p. S1F:
KAOLINUM, N. F.
Wiley, Samuel H.: A consular report calls attention to large de- —
posits of kaolin in Paraguay—Com. Rep. 1916, No. 200, p. 746.
Hess, Alfred F.: Kaolin and fullers’ earth, while usually con-
sidered synonymous, have different compositions, as shown by the
following table:
Si0>2. A1,03. Fe,03. CaO. | MgO. | Alkalies.| Water.
Kaolin. dea dle aed 45. 40 37.34 1.92 0.
Fullers’ earth..........---..--.- 57. 26 18. 33 1.87 2.
J. Am. M. Assoc. 1916, v. 66, p. 106-107.
Lloyd, John Uri: An account of the discovery of the alkaloidal
affinities of hydrous aluminum silicate—J. Am. Pharm. Assoc, 1916,
v. 5, p. 881-390, 490-495. ;
Rapp: A description of a method for testing the power of bolus
alba to absorb water.—Chem. Zentralbl. 1916, v. 87, part 2, p. 349.
207
E’we, G. E.: One lot, labeled “Terra Alba,” consisted of calcium
} sulphate—Proc. Pennsylvania Pharm. Assoc. 1916, p. 118.
i
:
>
fe
»
Rappaport, V.: Further observations on the use of kaolin to re-
' move diphtheria bacilli from the nose and throat—J. Am. M. Assoc,
- 1916, v. 66, p. 943-945.
KAVA, N. F.
Murakami, S.: According to Winzheimer, the crystallin constitu-
ents of kava are 0.3 per cent metisticin, 0.268 per cent $-metisticin,
~ and 0.184 yangonin. The author finds the relative proportions re-
' versed.—J. Pharm. Soc. Japan, 1916, No. 411, p. 393. see also Chem.
| Abstr. 1916, v. 10, p. 2386.
KINO.
Memminger, Lucien: A consular report dealing with the produc-
tion of kino in northern Malabar.—Com. Rep. 1916, No. 227, p.
1178-1179.
KOLA, N. F.
Anon.: The alkaloidal content of 10 samples of kola nuts, dried,
assayed from 1.34 to 2.4 per cent of alkaloids—Proc. Pennsylvania
Pharm. Assoc. 1916, p. 119.
Roberts, J. G.: One lot of kola nut examined contained 1.44 per
cent of alkaloids—Proc. Pennsylvania Pharm. Assoc. 1916, p. 114.
Swift, E. G.: Two samples of kola examined assayed 1.79 and
1.94 per cent of caffeine, respectively —Oul, Paint & Drug Rep. 1916,
y. 90, No. 16, p. 46.
Vanderkleed, C. E.: The caffeine content of 10 lots of kola exam-
ined ranged between 1.4 and 2.02 per cent. The average was 1.582
per cent.—J. Am. Pharm. Assoc. 1916, v. 5, p. 540.
LAC FERMENTATUM, N. F.
Anon.: Only fresh cow’s milk should be used in preparing kumyss,
as pasteurized milk does not yield a very gocd product.—N. A. R.
D. J. 1916, v. 23, p. 150.
Chouttinene, Anterro: Results obtained in determinations of the
acidity of fermented milk indicate that a standard solution of potas-
sium hydroxide is the most suitable for titration.—J. pharm. et chim,
1916, v. 14, p. 112, from Pharmazevtizeski J. 1916, p. 110.
LAC VACCINUM, N. F.
roldby, F.: A note calling attention to a so-called “synthetic ”
milk which is assumed to be an emulsion prepared from the soya
bean.—Pharm. J. 1916, v. 97, p. 214.
Barthelow, Paul: A history of condensed milk with a note on its
therapeutic uses.—Med. Rec. 1916, y. 90, p. 284-286.
208
Anon.: According to a German patent, sugar-free milk 1s prepared —
by dialyzing homogenized milk in thin layers at a temperature of
about 60° C. An abstract—Pharm. Weekblad, 1916, v. 53, p. 203.
Bosworth, Alfred W., and Van Slyke, Lucius L.: A comparison
of the composition of cow’s milk, goat’s milk, and human milk.—
J. Biol. Chem. 1916, v. 24, p. 187-189.
Van Slyke, Lucius L., and Bosworth, Alfred W.: A study of the
chemical changes which take place in the souring of milk.—J. Biol.
Chem. 1916, v. 24, p. 191-202.
Ackermann, Ed.: Some new contributions pertaining to the
analysis of milk.—Schweiz. Apoth.-Ztg. 1916, v. 54, p. 573-578.
Pégurier, G.: A scheme for the rapid examination of milk in the
field—Répert. pharm. 1916, v. 28, part 1. p. 1-3.
Koning, C. J., and Mooij, W. C.: A presentation of analytical
data obtained in the examination of milk, and comments thereon.—
Pharm. Weekblad, 1916, v. 53, p. 25-83, 50-59.
Hersey, C. B.: A comparison of sevhios for the estimation ée
case] . & Eng. Chem. 1916, y, 8, p. 335-336; see also
Analyst (The), 1916. v. 41, p. 203.
Osborne, Thomas B., and Wakeman, Alfred J.: A report of an
experimental study to determine the distribution of the phosphatides
in milk.—J. Biol. Chem. 1916, v. 28, p. 1-9.
van der Harst, J. C., and Koers, C. H.: Data showing the effect
of the presence of goat’s nulk on the physical and chemical con-
stants of cow’s milk.—Pharm. Weekblad, 1916, v. 53, p. 1551-1553.
Kolthoff, I. M.: Comments on the tests for the presence of alcohol
in milk.—Pharm. Weekblad, 1916, v. 53, p. 1589-1600.
Kxolthoff, I. M.: Notes on the detection of preservatives and color-
ing matter in milk—Pharm. Weekblad, 1916, v. 58, p. 1609-1618.
Hinks: Notes on the persistence of hydrogen dioxide in milk. A
case is cited in which 0.2 per cent added to fresh milk was still
present after 18 months.—Drug. Cire. 1916, v. 60, p. 702.
Grimmer, W.: A description of a new procedure for carrying out
the peroxidase reaction in milk. An abstract—Schweiz. Apoth.-
Zte. 1916, v. 54, p. 125-126.
Campbell, H. C.: Notes on the value of the sediment test as an
indication of the number of bacteria present in milk. From ex-
periments, the author concludes that there is no relation between the
sediment or dirt collected and the number of bacteria present. An
abstract.—Pharm. J. 1916, v. 97, p. 463.
Frost, William D.: A comparison of a rapid method of counting
bacteria in milk with the standard plate method.—J. Infee. Dis. .
1916, v. 19, p. 273-287.
Anon.: Provisional report of the laboratory section of the Ameri- _
can Public Health Association on standard methods for the bae-
209
sridlogical analysis oe milk.—Am. J. Public Health, 1916, y. 6,
. 1315-1325.
Anon.: The addition of lime water to cow’s milk for infant feed-
ng is unnecessary, as investigations by Holt have shown the presence
f a large excess of calcium salts in the milk itself—J. Am. M.
Assoc. 1916, v. 67, p.-1318.
LAPPA, N2 BF:
Roberts, J. G.: A shipment of tough, woody, old burdock root
greaking with an uneven fracture was rejected, as only root collected
from plants of the first year’s growth is desired.—Proc. Pennsyl-
yania Pharm. Assoc. 1916.
- Patch, E. L.: One lot of burdock root examined yielded 20.8 per
cent of ash. Usually the yield is from 7 to 10.5 per cent.—J. Am.
Pharm. Assoc. 1916, v. 5, p. 537.
LEPTANDRA, N. F.
q Anon.: Information relative to the cultivation and collection of
Culver’s root is given.—N. A. R. D. J. 1916, v. 23, p. 234-238.
LIMONIS CORTEX.
Holmes, E. M.: The source of lemon peel is given as Citrus medica
Limonum (Risso). Hook, f. Linneus is, however, responsible for the
name JZ/edica, which is usually spelled with a eee initial letter,
the adjective being a proper one, and refers to the fact that the
lemon is supposed to have been a native of Media.—Pharm. J. 1916,
. 97, p. 485.
LINIMENTA.
Tice, William G.: Of eight samples of different liniments exam-
ined, two were below standard.—Rep. New Jersey Dept. Health,
BLGSp. 72.
. LINIMENTUM CAMPHORA.
Anon.: A description of a simple method for the determination of
‘the camphor content of camphor liniment.—Apothecary, 1916, v. 13,
No. 2, p. 36.
. Ree Willis G.: Data showing the camphor content of a num-
ber of samples of camphor liniment prepared by pharmacy students:
at the University of Buffalo—Proc. New York Pharm. Assoc. 1916,
p- 250-251.
Lea, E. J.: A variation of from 50 to 100 per cent from the U.S. P.
standard was noted in samples of camphorated oil examined.—Bull.
California Bd. Health, 1916, y. 12, p. 48.
110095°—19——14
210
Anon.: A correspondent cites a case of poisoning in which a child
two years of age was given a teaspoonful of camphor liniment in
mistake for castor oil. It is suggested that this preparation be
labeled “ poison.”—Drug. Cire., 1916, v. 60, p. 85.
Table showing some of the analytical results reported for camphor liniment.
Number of samples—
Reporters. Sa References.
Examined.| Rejected.
| J
BSC Pe eee Se ae peter Meee eee 9 | 4 Bull. Vermont Bd. Health, 1916, v. 17, No. 2.
Casey, Wen encase een 6 | 1 Bull. Michigan D. & F. Dept., 1916, No. 252-255,
| |p. 9.
Wea We. Vesscen ates cee eee 9 7 Bull. California Bd. Health, 1916, v. 1, p. 643;
| _ V. 12, p. 220. .
SUNSON AAV a eee 36 17 | Proc. North Dakota Pharm. Assoc., 1916, p. 111.
eidide vA WEEN yh Se Ea 14 4 Bull. Mich D. & F. Dept., 1916, No. 244-247, p. 20:
No. 250-251, p. 16.
LINIMENTUM SAPONIS.
Anon.: The solidification of soap liniment frequently com-
plained of is due to the use of castile soap in bars which contains
a large proportion of water. This necessitates the use of a smaller
amount of alcohol, and solidification either partly or wholly is the
result.—N..A, B.D: J. 1916; 9923, p--193:
Anon.: A number of samples of soap liniment recently examined
for alcoho] content in the Mulford Analytical Laboratories gave the
following results upon plain distillation by the U. S. P. method:
99.0, 97.7, 97.3 and 99.9 per cent. The volatile oil which distills over
with the alcohol apparently has but little effect upon the ultimate —
result.—Drug. Circ. 1917, v. 61, No. 9, p. 29.
LIQUORES.
Diekman, George C.: Three solutions have been added to the
U.S. P. and three have been deleted. A further reduction in the
number of official liquors might have been made without seriously
interfering with the value of the Pharmacopoeia—Pract. Drug.
1916, v. 34, No. 10, p. 25.
Schneider, Albert: Locke’s, Adler’s, and Fischer’s solutions should
have been introduced into the U. S. P., as they are required and ex-
tensively used in hospital as well as private practice and in biologi-
cal experiments and Jaboratory work.—Drug. Cire. 1916, v. 60, p. 693,
Penfold, Frederick: Some suggestions for improvements in the
Ph. Brit. method of preparing Liquor Bismuthi et Ammonii Citra-
tis.—Pharm. J. 1916, v. 97, p. 567-570.
Anon.: A short description of Gordon Surr’s method for diluting
solutions to definite specific gravity —Drug Topics, 1916, v. 31, No.
1, p. 16-17,
211
Zotier, V.: General formulas for the preparation of isotonic solu-
ions are presented.—Bull. sc. pharmacol. 1916, v. 23, p. 219-225.
Becker, M.: A paper dealing with the history and methods of
preparation of intravenous solutions.—J. Am. Pharm. Assoc. 1916,
by. 5, p. 846.
Neilsen, C. O.: A method for the preparation of Liquor Ferri
Caseinati, based on careful experiments, is described. An abstract.—
Norges Apotek. Tidsskr. 1916, v. 24, p. 201-204.
Burmann, James, jr.: Notes on the use of the Ringer-Locke serum
for the preparation of stable medicinal solutions—Chem. Abstr.
1916, v. 10, p. 2614.
~ Meunier, L.: A presentation of experimental data showing the
advisability of employing isotonic solutions in the administration
‘of medicines by mouth. An abstract.—Pharm. J. 1916, v. 97, p. 569.
LIQUOR ALUMINI ACETATIS, N. F.
_ <Anon.: A working formula for the preparation of the solution of
‘aluminum acetate is given.—N. A. R. D. J. 1916, v. 21, p. 763.
Anon.: If the solution of aluminum acetate is properly prepared,
the lead should be completely precipitated, as the lead sulphate
formed is practically insoluble and a calculated excess of aluminum
sulphate is directed to be employed. There should, therefore, be but
slight danger from lead poisoning following the use of this solu-
tion.—J. Am. M. Assoc. 1916, v. 67, p. 1035.
_ Anon.: A discussion of the treatment of burns by the use of
‘aluminum acetate and subacetate—J. Am. M. Assoc. 1916, v. 67,
/p- 829.
¢ LIQUOR ANTISEPTICUS, N. F.
Anon.: The old formula for antiseptic solution was better than
‘that of the N. F. IV, and it is feared that the revised formula will
‘not meet with the approval of physicians generally.—N. A. R. D. J.
£916, v. 23, p. 150.
Anon.: In order to produce an antiseptic solution which will be
‘uniform at all times, it is suggested that the pharmacist keep oa
hand a stock solution of the thymol and volatile oils in alcohol.
‘The quantities of the materials in this solution are such that 15 mils
are to be used in preparing a thousand mils of antiseptic solution.—
ey. A. R. D. J. 1916, v. 21, p. 861.
5 LIQUOR ANTISEPTICUS ALKALINUS, N. F.
3 Anon.: A discussion of modified formulas for the preparation of
‘alkaline antiseptic solution—N. A. R. D. J. 1916, v. 21, p. 1121.
_ Anon.: A far better preparation would have resulted if the oil
of peppermint and methyl] salicylate had been replaced with 10:
grams of sodium chloride.—N. A. R. D. J. 1916, v. 23, p. 151.
Ps
>
»
212
LIQUOR ARSENI ET HYDRARGYRI IODIDI.
Rosin, Joseph: Experimental data are presented showing the rate
of oxidation of the arsenous iodide in Donovan’s solution and its
bearing on the U. S. P. assay method.—J. Am. Pharm. Assoe. 1917,
v. 6, p. 951-952.
LIQUOR AURI ET ARSENI BROMIDI, N. F.
Anon.: The following precaution to be observed in the prepara-
tion of the solution of bromide of gold and arsenic is recommended
for the new edition of the N. F.: “If a fume chamber is not acces-
sible, the disagreeable and injurious effects of the bromine upon the
mucous membrane of the operator may be largely prevented by plac-
ing around him several shallow vessels containing a weak solution
of ammonia.”—N. A. R. D. J. 1916, v. 21, p. 1065.
LIQUOR CALCIS.
Hostmann, Jeannot: A note on the contamination of limewater
with sulphide as a result of the use of red rubber tubing in siphon-
ing off the limewater from the container.—C. U. C. P. Alumni J.
1916, v. 23, p. 5.
Anon.: Of a total of 59 samples of limewater examined, 6 were
found to be below standard.—Proc. Maryland Pharm. Assoe. 1916,
p- 84-94.
Anon.: Of 13 samples of limewater examined, 1 was below stand-
ard.—Proc. Minnesota Pharm. Assoc. 1916, p. 211.
Hostmann, Jeannot: Four of 20 samples of limewater examined
were low in calcium hydroxide content—Proc. New Jersey Pharm.
Assoc. 1916, p. 78. .
Sayre, L. E.: Of four samples of limewater examined, one was
adulterated.—Bull. Kansas Bd. Health, 1916, p. 12.
LIQUOR CALCIS SULPHURATA, N. F.
Chapin, R. N.: Descriptions of new methods for the analysis of
Jime-sulphur solutions.—J. Ind. & Eng. Chem. 1916, v. 8, p. 151-156;
see also Analyst (The), 1916, v. 41, p. 184-186. :
LIQUOR CHLORI COMPOSITUS, N. F.
Race, Joseph: On the use of calcium hypochlorite and ammonium
oxalate for the chlorination of water.—Lancet, 1916, vy. 191, p. 71-72.
Hallvorson, M. B.: Clinical notes on the use of compound solution:
of chlorine in the treatment of pneumonia and tuberculosis —Jour-
nal-Lancet, 1916, v. 36, p. 596-600. . |
213
LIQUOR CRESOLIS COMPOSITUS.
~ Anon.: Notes on the preparation of compound solution of cresol.—
N. A. R. D. J. 1916, v. 22, p. 480-481.
Richter: A formula for the preparation of the compound solution
without the formation of glycerol is described. Instead of linseed
Keulemans, N.: A note on the quantitative determination of cresol
in the compound solution of cresol—Pharm. Weekblad, 1916, v. 53
p: 259.
Vivario, R.: Data showing the comparative bactericidal powers of
compound solution of cresol prepared according to the methods given
im the different pharmacopeeias.—Pharm. Weekblad, 1916, v. 53, p.
629-631.
?
LIQUOR FERRI ALBUMINATA, N. F.
Anon.: Notes on the preparation of solution of iron albuminate
with suggestions for changes in the N. F. formula.—N. A. R. D. J.
® 1916, v. 21, p. 1279.
Cook, E. Fullerton: Instead of using the dry and usually bad
smelling albuminate in the preparation of the solution of iron al-
buminate, fresh egg albumin is used, and thus the unpleasant odor
often noticed in this preparation has been eliminated.—Drug. Cire.
1916, v. 60, p. 542.
. LIQUOR FERRI CHLORIDI.
Carlson, C. E.: A report of investigations on the preparation and
preservation of the solution of ferric chloride and the alcoholic solu-
) tion of ferric chloride.—Svensk farm. Tidskr. 1916, v. 20, p. 184+
5135, 153-155.
LIQUOR FERRI ET AMMONII ACETATIS.
Anon.: Explanatory notes on the preparation of solution of iron
) and ammonium acetate.—N. A. R. D. J. 1916, v. 22, p. 273-274.
_ Wood, H. C., jr.: In a discussion on the misuse of Basham’s mixture
‘in the treatment of Bright’s disease, the author states that the at-
tempt to justify the use of this solution in nephritis on the ground of
its adding the diuretic effect of the ammonium acetate to the chalyb-
eate action of the iron verges on sophistry.—J. Am. M. Assoc. 1916,
y. 66, p. 1071-1072.
LIQUOR FERRI PEPTONATI, N. F.
Lami, Pio: A description of a method for preparing peptonate of
iron for hypodermic medication.—Boll. chim.-farm, 1916, vy. 55, p.
ep) ee
214
LIQUOR FERRI PEPTONATI ET MANGANI, N. F.
Anon.: In commenting on the N. F. directions for the preparation
of solution of peptonate of iron and manganese, it is stated that there
appears to be a discrepancy in that the amount of sodium hydroxide
to be dissolved in 9 parts of water is not specified. The amount of
flavoring, especially of vanillin, is thought to be exceptionally small—
N. A. R. D. J. 1916, v. 23, p. 413-415.
Anon.: Directions for making the solution of iron peptonate with —
manganese according to the method suggested by McElhenie are given, ©
Several other formulas are also discussed—_N. A. R. D. J. 1916, v.
21, p. 963-964.
LIQUOR FORMALDEHRYDI.
Anon.: Formaldehyde, its manufacture and applications in phar- —
macy.—Farm. Espafi. 1916, v. 48, p. 176-179, 193-196.
Vanderkleed, C. R., and E’we, G. E.: Experiments with the U. 8S.
P. assay method for formaldehyde indicate that 30 minutes is too
short a time to allow the mixture of solution of formaldehyde, hy- —
drogen peroxide, and normal alkali to stand, as oxidation is not
complete in this period. <A better plan is to allow the mixture to
stand until no more gas bubbles are noticed on shaking, which oe-
curs after an hour or two.—Proc. Pennsylvania Pharm. Assoc. 1916,
p. 277; see also J. Am. Pharm. Assoc. 1916, v. 5, p. 713-714.
Collins, R. J., and Hanzlik, P. J.: A description of a colori-
metric method for the estimation of free formaldehyde and hexa-
methylenamine. Jorissen’s phloroglucinol reagent is employed.—J.
3iol. Chem. 1916, v. 25, p. 231-237.
Kunz, Herman: Analytical data showimg the amount of copper
present in formaldehyde solutions prepared by the use of a copper
spiral catalyser—Apoth.-Ztg. 1916, v. 31, p. 66-67.
MeGill, A.: Of 68 samples of formalin examined, 4 were below
standard.—Bull. Lab. Inl. Rev. Dept. Canada, 1916, No. 333, p. 5.
Patch, E. L.: One lot of solution of formaldehyde examined con-
tained copper.—J. Am. Pharm. Assoc. 1916, v. 5, p. 538.
Roberts, J. G.: Only two of nine lots of liquor formaldehyde ex- —
amined complied with the U. S. P. specifie gravity requirement of
1.075 to 1.081; they were all high and showed specific gravities rang-
ing from 1.082 to 1.099.—Proc. Pennsylvania Pharm. Assoe. 1916,
p. 114.
Todd, A. R.: Of 11 samples of formaldehyde examined, 4 were
rejected.—Bull. Michigan D. & F. Dept. 1916, No 244-247, p. 20.
Vanderkleed, C. E.: All of the samples of solution of formalde-
hyde examined exceeded the U. S. P. requirements of 1.075 to 1.081
for specific gravity. The average was between 1.082 and 1.087. Most
.
215
the samples gave reactions for chloride, sulphate and caleium, but
were otherwise U. S. P.—J. Am. Pharm. Assoc. 1916, v. 5, p. 538.
Earp, Samuel E.: A discussion of the physiologic and toxic action
of formaldehyde, with a report of three cases of poisoning by for-
malin.—New York M. J. 1916, v. 104, p. 391-392.
LIQUOR HYDRARGYRI NITRATIS, N. F.
_ Diekman, George C.: The deletion of the solution of mercuric ni-
trate will hardly attract attention. Why this solution should ever
have been honored with a place in the Pharmacopoeia is a mystery
to most of us.—Pract. Drug. 1916, v. 34, No. 10, p. 25.
LIQUOR HYDROGENII DIOXIDI.
Olea, Gregorio: Notes on the preparation of solutions of hydro-
_ gen dioxide for medicinal use-—Farm. Espami. 1916, v. 48, p. 151-152.
_ Khouri, Joseph: A note on the preparation and conservation of
solution of hydrogen dioxide containing iodine.—J. pharm. et chim.
1916, v. 14, p. 356-359.
Walton, James H., and Jones, De Witt O.: Data showing the
catalytic decomposition of hydrogen peroxide in certain nonaqueous
solutions.—J. Am. Chem. Soe. 1916, v. 38, p. 1956-1961.
_ Anon.: A deserrption of'a bottle for keeping highly concentrated
_ (30 per cent) solutions of hydrogen peroxide—Ztschr. angew. Chem.
1916, v. 29, p. 208.
| Emell, Henrik: From the difference in the results obtained in
titrating commercial hydrogen peroxide with phenolphthalein and
- iodoeosin as Indicators, it is concluded that both, a mineral acid and
a weak organic acid, are present. The nature of the latter could not
he determined.—Ztschr. anal. Chem. 1916, v. 55, p. 452-459.
‘ von Bertlan, J. A.: Experimental data obtained in the evaluation
_of hydrogen dioxide solution by titration with stannous chloride.—QJ.
/ Chem. Soc. Lond. 1916, v. 110, p. 393 from Chem.-Ztg. 1916, v. 40,
; p. 373.
- Anon.: Two samples of peroxide of hydrogen examined were re-
-jected.—Rep. Wyoming D. F. & O. Com. 1916, v. 2, No. 7, p. 33.
— <Anon.: One of two samples of solution of hydrogen dioxide ex-
amined was rejected for being below standard.—Rep, Connecticut D.
& F. Com. 1916, p. 19.
- Roberts, J. G.: One lot of hydrogen peroxide solution examined
‘contained about fifteen times the amount of arsenic permitted by the
.S. P. Other lots had too high an acidity and yielded too much
‘residue upon evaporation.—Proc. Pennsylvania Pharm. Assoc. 1916,
p. 113,
216
Tice, William G.: Of four samples of solution of hydrogen
dioxide examined, one was below standard.—Rep. New Jersey Dept.
Health, 1916, p. 72. 7
Todd, A. R.: Of five samples of hydrogen peroxide examined, two
were rejected.— Bull. Michigan D. & F. Dept. 1916, No. 244-247, p. 20.
Vanderkleed, C. E.: Twenty-three lots of solution of hydrogen
dioxide examined were satisfactory with the exception that two of
them gave total solids amounting to 0.0479 and 0.340 gm. per 20
cubie centimeters instead of 0.030 as required by the U. S. P..—J. Am.
Pharm. Assoc. 1916, v. 5, p. 539.
LIQUOR HYPOPHYSIS.
Xrayser II.: The term “ Liquor Hypophysis” is said to be un-
fortunate, since it implies a preparation made from the entire pitui--
tary body, whereas only the posterior lobe, or infundibulum, is used.—
Chem. & Drug. 1916, v. 88, No. 1913, p. 41. .
Puckner, W. A.: “Solution of Hypophysis—Squibb” is a steril-
ized aqueous solution of the water-soluble active principles of the
posterior lobe of the pituitary body of cattle free from chemical pre--
servatives. It is standardized according to the physiological method |
of G. B. Roth.—_J. Am. M. Assoc. 1916, v. 67, p. 745.
Watanbe, Walter K., and Crawford, Albert C.: Pituitary extracts,
when prepared by certain methods, yield color reactions which sug-
gest the presence of epinephrine or an epinephrine-like compound.—
J. Am. M. Assoc. 1916, v. 66, p. 604; see also Rep. Therap. Res. Com.
1916, v. 5, p. 62-75.
Fiihner, Hermann: From experiments it is concluded that the
active substances of the pituitary body are not esters of choline.—
3iochem. Ztschr. 1916, v. 76, p. 232-247.
Fenger, F.: A second contribution to our knowledge of the com-
position and properties of the posterior lobe of the pituitary body—
J. Biol. Chem. 1916, v. 25, p. 417-422.
Rowe, L. W.: A review of the methods used in pituitary standardi-
zation.—J. Lab. & Clin. Med. 1916, v. 2, p. 120-129,
Pittenger, Paul S.: An illustrated description of an isolated uterus”
method for standardizing pituitary extracts——Mulford’s Vet. Bull.
1916, v. 7, p. 128-136.
Hoskins, R. G.: From an investigation of the action of commer-
cial pituitary extracts, it is concluded that it is unsafe to rely on these
preparations for therapeutic use as stimulants for peristalsis ——dJ.
Am. M. Assoc. 1916, v. 66, p, 733.
Miller, Joseph L.: A study of the relation of the hypophysis to
certain clinical manifestations and the therapeutic application of its
extracts—Am. J. M. Se. 1916, v. 152, p. 549-560.
217
Pal, J.: A report of investigations dealing with the action of pitu-
itary extract on the systemic and glandular secretions in general.—
Deutsch. med. Wehnschr. 1916, v. 42, p. 1030-1033.
Goetsch, Emil: Researches to determine the influence of pituitary
feeding upon growth and sexual development.—J. H. Hosp. Bull.
1916, v. 27, p. 29-50.
_ Shamoff, V. N.: A study of the action of pituitary extracts upon
the isolated intestinal loop. There exists in the posterior lobe a sub-
_ stance which has an action similar to that of epinephrine.—Am. J.
Physiol. 1916, v. 39, p. 268-278; see also Chem. Abstr. 1916, v. 10, p.
1374.
Hoppe-Seyler, J.: On the relation of the pituitary body to diabetes
insipidus and the treatment of the latter with pituitary extracts.—
Chem. Abstr. 1916, v. 10, p. 1053; see also Miinch. med. Wehnschr.
1915, v. 62, p. 1633-1635.
MeNeile, L. G.: A report of a case of rupture of the uterus due to
the administration of pituitary extract to a woman with an obliquely
contracted pelvis. An abstract—J. Am. M. Assoc. 1916, v. 67, p. 113.
LIQUOR MAGNESII CITRATIS.
Anon.: A working formula for the preparation of six bottles of
magnesium citrate solution is given—N. A. R. D. J. 1916, v. 22,
p.;222. ,
Anon.: Comments on the formula for the preparation of the solu-
tion of magnesium citrate—N. A. R. D. J. 1916, v. 21, p. 1021-1022.
Blomberg, C.: A description of an improved Ph. Ndl. [LV method
for the preparation of the solution of magnesium citrate—Pharm.
Weekblad, 1916, v. 53, p. 1382-1386.
Léger, E.: Notes on the changes which take place in the composi-
tion of magnesium citrate on keeping—J. pharm. et chim. 1916, v.
13, p. 209-214; see also Farm. Espan. 1916, v. 48, p. 310-312; Chem.
' Abstr. 1916, v. 10, p. 2027.
-Anon.: Of 35 samples of solution of magnesium citrate exaniuned,
21 were found to be below standard.—Rep. Connecticut D. & F.
Com. 1916, p. 19.
LIQUOR PEPSIN ANTISEPTICS, N. F.
Anon.: There are altogether too many official pepsin preparations,
and not one of them contains a sufficient amount of pepsin per dose to
be an efficient medicinal agent.—N. A. R. D. J. 1916, v. 23, p. 151.
LIQUOR PEPSINI AROMATICUS, N. F.
Anon.: Were it not for the fact that the pepsin content of this
preparation is somewhat small, it would be by far the most efficient
pepsin preparation in the official materia medica.—N. A, R. D. J.
- 1916, v. 23, p. 414.
218
LIQUOR PICIS CARBONIS, N. F.
Anon.: A much better preparation than that prepared by the offi- .
cial process results from digesting the coal tar in a tincture made by —
macerating the quillaja in alcohol.—N. A. R. D. J. 1916, v. 23, p. 152.
LIQUOR POTASSZ CHLORINATA, N. F.
Comte: A discussion of the volumetric assay of chlorinated lime,
Javelle water, and Dakin’s solution by the usual iodometric
method.—J. pharm. et chim. 1916, v. 1916, v. 14, p. 232.
LIQUOR POTASSIT ARSENITIS.
Dallande: The author suggests boiling the aqueous mixture of
arsenic trioxide and sodium bicarbonate in an Erlenmeyer flask in-
stead of a dish in order to avoid the loss of arsenic.—Drug. Cire.
1916, v. 60, p. 85.
Stinson, Ray: Of 60 samples of Fowler’s solution examined, 11
were below standard and 5 were above.—Proc. North Dakota Pharm.
Assoc. 1916, p. 111.
LIQUOR SOD CHLORINAT:.
Elledge, H. G.: The pink color observed in certain hypochlorite
bleaching solutions is attributed by the author to the presence of
traces of sodium permanganate, the latter being derived from the
bleaching powder used.—J. Ind. & Eng. Chem. 1916, v. 8, p. 780-781.
Valery, Lucien: A note on the stability of hypochlorites in very
dilute solutions, with special, reference to their employment for the
sterilization of water—Compt. rend. Acad. se. 19i6, v. 162, p. 326—
327.
Comte: A discussion of the volumetric assay of chlorinated lime,
Javelle water, and Dakin’s solution by the usual iodometric
method.—J. pharm. et chim. 1916, v. 14, p. 232. ie
Penau, H.: In a discussion of the sterilization of water in the field
the author calls attention to the chemical composition of the solution
of chlorinated soda prepared by double decomposition and of the
relative stability of the solution—J. pharm. et chim. 1916, y. 13,
p. 377-385.
Daufresne, M.: Notes on the technique for preparing hypochlorite
solutions intended for surgical use—J, Am. M. Assoc. 1916, v. 67,
p. 1795.
Anon.: Dakin’s new antiseptic may be looked upon as simply La-
barraque’s solution of sodium hypochlorite NaOCl made neutral
with boric acid. The solution loses its strength on keeping. An
important point in connection with the preparation of the solution
which seemingly has been overlooked is that the strength of the
219
bleaching powder is not determined. As is well known, this product
is exceedingly variable—J. Am. M. Assoc. 1916, v. 67, p. 1108.
_ Editorial: A résumé of the report of H. D. Dakin and H. G. Car-
lisle on the preparation and use of electrolytic hypochlorite for hos-
| pital ships—Brit. M. J. 1916, v. 1, p. 455-456.
Carrel, A.: Notes on the preparation and preservation of Carrel-
Dakin solution.—J. Am. M. Assoc. 1916, v. 67, p. 1777-1778.
Anon.: A note on the boricated solution of sodium hypochlorite
prepared according to the formula of Dakin.—J. pharm. et. chim.
1916, v. 14, p. 263.
Doyen, E.: A study of the action of the official sodium hypo-
_chlerite and calcium hypochlorite solutions of the Ph. Fr. on spores
_ in the treatment of infected wounds.—Compt. rend. Soe. biol. 1916,
_ v.79, p. 335-336.
_ Milroy, Thomas H.: A study of the action of hypochlorites and
allied substances on proteins, and their behavior on injection.—
Biochem. J. 1916, v. 10, p. 453-465.
__ Dakin, H. D.: A study of the behavior of hypochlorites on in-
_ travenous injection and of their action on blood serum.—Brit. M. JJ.
- 1916, v. 1, p. 852-854; see also Chem. Abstr. 1916, v. 10, p. 2374.
_ Fraser, John, and Bates, H. J.: A report on the treatment of
acute toxemia secondary to gas gangrene by the intravenous injection
of a solution of hypochlorous acid.—Brit. M. J. 1916, v. 1, p. 83-86.
Dalton, Frederick J. A.: An enumeration of the advantages of the
use of sodium hypochlorite in the treatment of septic wounds.—Brit.
M. J. 1916, v. 1, p. 126-128; see also J. Am. M. Assoc. 1916, v. 66, p.
693; Chem. Abstr. 1916, v. 10, p. 1380.
Cordova, Raul F.: Experimental data showing the therapeutic
_ value of hypochlorous acid.—Brit. N. J. 1916, v. 1, p. 651-652.
Fi Mayer, C.: A discussion of the advantages of the solution of
' magnesium hypochlorite over that of sodium hypochlorite. An
- abstract—J. Am. M. Assoc. 1916, v. $6, p. 98.
. Dubard: As a disinfectant for wounds, a 2.5 per cent solution of
~ magnesium hypochlorite is stated to be superior to the solution of
- sodium hypochlorite or Dakin’s fluid—J. Am. M. Assoc. 1916, y. 67,
im p. 1118.
LIQUOR SODII BORATIS COMPOSITUS, N. F.
_ Anon.: A note on the preparation of compound solution of sodiurt
borate.—N. A. R. D. J. 1916, v. 21, p. 15.
LIQUOR ZINCI CHLORIDI.
Anon.: A description of a new method for the preparation of the
solution of chloride of zine.—Schweiz. Apoth—Ztg. 1916, y. 54,
» p. 598 from Pharm. Ztg. 1916, v. 61, p. 130.
220
Bateman, E.: Data showing the relation between the specific grav-
ity of zinc chloride solutions and their concentrations.—Chem. Eng.
1916, v. 24, p. 131-132.
LITHIT CARBONAS.
Wood, H. C., Jr.: It is evident that science lends no support to
the use of lithium in medicine. Any judgment in favor of this |
element must be based solely on bedside experience.—J. Am. M.
Assoc. 1916, v. 66, p. 1069-1070.
Haskins, Howard D.: A study of the uric acid solvent power of
urine after the administration of piperazin, lysidin, lithium carbonate,
and other alkalies.—Rep. Therap. Res. Com. 1916, v. 5, p. 112-123.
LITHIT SALICYLAS, N. F.
Anon.: A reprint of the standards proposed for lithium salicylate
by the committee on unofficial standards——J. Am. Pharm. Assoe.
1916, v. 5, p. 87. . 3
LOBELIA.
Anon.: Information relative to the cultivation and harvesting of
lobelia is given—N. A. R. D. J. 1916, v. 23, p. 505-508.
Vanderkleed, C. E., and E’we, G. E.: In a note on the assay of
lobelia preparations, the authors report that quite concordant results
with excellent end points can be obtained by using the Volhardt
method of titration—J. Am. Pharm. Assoc. 1916, v. 5, p. 718.
Anon.: The alkaloidal content of one sample of lobelia assayed
was above standard—Proc. Pennsylvania Pharm. Assoc. 1916, p.
119;
3rowne, G. R.: A report of some animal experiments with
lobeline sulphate——Am. J. Clin. Med. 1916, v. 23, p. 678-679.
LUPULINUM, N. F.
Young: Wallace, J.: A consular report of the lupulin trade of
Austro-Hungary.—Com, Rep. 1916, No. 118, p. 587.
Scoville, W. L.: The ash content of five lots of lupulin examined —
ranged between 2.5 to 14.1 per cent.—J. Am. Pharm. Assoc. 1916, v5
5, p 540.
Swift, E. G.: Fourteen samples of ]upulin examined yielded from
8.0 to 44.8 per cent of ash. Only 3 of the samples yielded less than |
10 per cent, and 3 others between 10 and 15 per cent.—Oil, Paint &
Drug Rep. 1916, v. 90, No. 16, p. 46.
Vanderkleed, C. E.: The ether-soluble portion of 10 lots of lupu-
lin ranged between 44.2 and 69.2 per cent. The same samples
yielded from 7.72 to 284 per cent of ash—J. Am. Pharm. Assoc.”
1916, v. 5, p. 540.
221
MAGMA FERRI HYDROXIDI, N. F.
van der Feen, F.: Experimenta] data showing the osmotic pres-
sure of colloidal oxyhydrate of iron—Chem. Weekblad, 1916, vy. 13
p. 453-458.
’
MAGMA MAGNESI.
Anon.: It is not understood why the revisers of the U. S. P. use
the term “ Magnesiz ” in the Latin title for milk of magnesia when
“Magnesii” is used for all other preparations of magnesium.—
Drug Topics, 1916, No. 9, p. 7.
McNeery, W. W.: An improved formula for the preparation of
“magma of magnesia is described in detail—J. Am. Pharm. Assoc.
1916, v. 5, p. 611.
_ <Anon.: A criticism of the U. S. P. formula for preparing mag-
-nesia magma states that the choice of the flavoring agent should not
be left to the pharmacist.—N. A. R. D. J. 1916, v. 23, p. 11-12.
Anon.: In a discussion of a number of formulas for the prepara-
tion of milk of magnesia, it is stated that for some unknown reason
certain lots of magnesium sulphate are more difficult to hydrate than
others, and for this reason only the salt of pharmacopeceial purity
should be used.—N. A. R. D. J. 1916, v. 21, p. 1020-1021.
- Tice, William G.: Of three samples of milk of magnesia exam-
ined, one was below standard.—Rep. New Jersey Dept. Health, 1916,
p- (2.
MAGNESII CARBONAS.
Fischter, F., and Osterwalder, R.: A report of investigations to de-
termine the compostion of the precipitate obtained when an aqueous
solution of a magnesium salt is treated with ammonium carbonate
under different conditions.—Ztschr. anal. Chem. 1916, v. 55, p.
389-392 through Analyst (The), 1916, v. 41, p. 319-320.
Wanderkleed, C E.: Two of six lots of magnesium carbonate
examined were low in MgO ignition, assaying 92.6 and 94.8 per cent,
respectively. Five of the six samples contained calcium in excess of
the U. S. P. limits—J.Am. Pharm. Assoc. 1916, v. 5, p. 540.
MAGNESII CHLORIDI.
Bourdet, L.: A description of a method for determining the qual-
ity of magnesium chloride. Nitric acid is added and the resulting
nitrate is converted into the oxide by calcination. The amount of
pure magnesium chloride present is calculated after determining the
amount of water-insoluble matter, the weight of the nitrate prior to
calcining, and the total chlorine—QJ. pharm. et chim, 1916, y. 13,
p. 102-104.
222
MAGNESI CITRAS EFFERVESCENS, N. F.
Léger, E.: Observations on the change taking place in magnesium —
citrate upon keeping. From experiments it is concluded that the
magnesium citrate prepared according to the French Codex changes
from magnesium citrate containing seven molecules of water of
crystallization to the salt containing 13 molecules of water of crystal-
lization on aging.—J. pharm. et chim. 1916, v. 13, p. 209-214. .
Lea, E. J.: The samples of citrate of magnesia examined were not
made according to the U. S. P. Tartaric acid had been substituted
for citric acid and the proportion of the ingredients was not correet.—
Bull.,California Bd. Health, 1916, v. 12, p. 112.
MAGNESIT OXIDUM.
Scoville, W. L.: Caleined magnesia v aries much in lightness. Uni-
formity in this respect is very ‘desirable for stock preparations, but
less important for other purposes.—J. Am. Pharm. Assoc. 1916, v. 5,
p- 540.
Vanderkleed, C. E.: None of the samples of calcined magnesium
examined during the past year gelatinized with water as required by
the U. S. P., and most of them contaimed an excess of calcium over
the U. S. P. limits.—J. Am. Pharm. Assoc. 1916, v. 5, p. 540.
E’we, G. E.: Some of the lots of magnesium oxide examined
showed calcium in excess of the U. S. P. limits——Proe. Pennsylvania
Pharm. Assoc. 1916, p. 114.
Patch, E. L.: One of the four s samples of calcined magnesia ex-
amined yielded only 93.7 per cent of MgO after ignition. —J. is
Pharm. Assoc. 1916, v. 5, p. 540.
MAGNESIIT SULPHAS.
Grimbert, L.: The author calls attention to the presence of arsenic
iu commercial samples of magnesium sulphate. Three samples ex-
amined contained 0.47, 0.32, and 0.68 grams of arsenic, respectively,
per kilogr: . et chim. 1916, v. 13, p. 197.
Fleury, E.: The author, in commenting on the paper of Grim-
bert, recommends that the arsenic be determined by the method in-
volving the staining of mercuric chloride or silver nitrate paper and
not by the M: arm. et chim. 1916, v. 13, p. 385.
E’we, G. E.: One lot labeled “ Magnesium Sulphate—not more
than 20 per cent water” contained 25.5 per cent of water. Another
sample labeled “dried and powdered” contained 10.2 per cent of
water.—Proc. Pennsylvania Pharm. Assoc. 1916, p. 114.
Patch, E. L.: Of 15 lots of erystalline magnesium sulphate ex-
anined, only 1 was free from chloride. The others contained from
a trace to 0.50 per cent.—J. Am. Pharm. Assoc. 1916, v. 5, p. 540,
223
Street, John Phillips: All of the 37 samples of magnesium sul-
phate examined showed a high degree of purity—Rep. Connecticut
peric. Exper. Sta. 1916, part 4, p. 255.
~ Peek, Charles H., and Meltzer, Samuel J.: The employment of
magnesium sulphate (intravenously) as an anesthetic may prove to
be of practical value for the reason that it may cause simultaneously
moderate degree of relaxation of the muscular mechanism and
because the untoward effects can be rapidly reversed by the careful
administration of calcium chloride—J. Am. M. Assoc. 1916, v. 67,
p. 1131-1133.
Leonard, Edward A.: A report on the employment of intraspinal
injections of magnesium sulphate in the treatment of delirium tre-
/ mens.—J. Am. M. Assoc. 1916, v. 67, p. 509-510,
_ Meltzer, S. J.: An account of researches on the inhibitory prop-
erties of magnesium sulphate and their therapeutic application in
tetanus.—J. Am. M. Assoc. 1916, v. 66, p. 931-934.
Esmond, J.: A discussion on the use of magnesium sulphate solu-
tion in the treatment of burns with a report of one case—J. Am. M.
' Assoc. 1916, v. 67, p. 969-970.
MALVAE FOLIA, N. F.
| Anon.: A reprint of the standards for mallow leaves proposed by
_ the committee on unofficial standards.—J. Am. Pharm. Assoc. 1916,
y. 5, p. 87-88.
MANGANI DIOXIDUM PRAECIPITATUM.
Vanderkleed, C. E.: One Jot of manganese dioxide examined
' yielded some insolulsle residue in the test for antimony sulphide and
' insoluble substances, but was otherwise U. S. P.—J. Am. Pharm.
| Assoc. 1916, v. 5, p. 540.
MANGANI SULPHAS, N. F.
Anon.: A reprint of the standards for manganese sulphate pro-
_ posed by the committee on unofficial stand: . Pharm.
m Assoc. 1916, v. 5, p. 88.
Vanderkleed, C. E.: The moisture content of seven lots of man-
~ ganese sulphate examined ranged between 29.4 and 37.4 per cent.—
'J. Am. Pharm. Assoc, 1916, v. 5, p. 540-541.
MANNA.
Alsberg, C. L.: The tentative standards laid down by the Bureau
of Chemistry require that manna should yield not less than 75 per
cent of material (mannite) soluble in 90 per cent alcohol, not more
than 10 per cent of moisture, and not more than 3 per cent of ash.—
S. R. A.-Chem. 1916, No. 16, p. 30.
224
Rusby, H. H.: The definition of manna, taken in connection wit
the description, now permits the importation of “sorts,” provided
they be of good quality; a very desirable change.—Drug. Cire. 1916,
v: 60;'p. 537. as
Battandier, J. A.: A note on manna obtained from Olea Europea.
The excretion of manna was caused by the damage inflicted by the
larvee of a species of Cossus (goat moth).—dJ. pharm, et chim. 1916,
v, 13, p. 105.
MASSA HYDRARGYRI.
E’we, G. E.: One lot of blue mass, powdered, examined contained ©
38.5 per cent metallic Hg. The U.S. P. requirement is 35 per cent.— °
Proc. Pennsylvania Pharm. Assoc. 1916, p. 110.
Vanderkleed, C. E.: Two lots of blue mass powder examined con-
tained 32 and 31.3 per cent, respectively, of metallic mercury; both -
were below the standard of 33 per cent—J. Am, Pharm. Assoc. ;
1916) wv2.55)p:.500.
MATRICARIA.
Roberts, J. G.: Six to 10 per cent of stems was found in 10 samples
of matricaria (German) examined. The standard adopted for the
U. S. P. YX is 5 per cent.—Proc. Pennsylvania Pharm. Assoc. 1916,
p. 114. :
MEL.
Parry, Ernest J.: There is not a single word under “ Honey” in
the U. S. P. dealing with its examination by polarimetric methods, ~
whereas, comparatively trivial color reactions are given undue promi- —
nence.—Chem. & Drug. 1916, v. 88, No. 1913, p. 40.
Berger, Fr.: A continuation of an article on bee’s honey and wax
and their use as therapeutic agents——Schweiz. Apoth.-Zte. 1916,
v. 54, p. 450-454.
Lehmann, P., and Stadlinger, H.: The authors call attention to a
correction in H. Kretzschmar’s publication on the polarimetric
determination of sugar in honey by the method of Lehmann-Stad-
linger. Kretzschmar is stated to have used the wrong factor in
his computations—the algebraic difference between the two polarime- —
tric readings should have been multiplied by 5.7 instead of 7.5.—
Ztschr. Unters. Nahr.- p. Genussm, 1916, v. 31, p. 160-162.
Anon.: From experiments, G. Langer concludes that the albumen
present in honey is not derived from the pollen of flowers, but from
the saliva of the bees. An abstract.—Pharm. J. 1916, v. 96, p. 471,
Atkins, W. R. G.: A method for determining the sugars in honey —
is described. The aldehydic sugars are estimated by oxidation with
bromine and the ketonic fructose by polarimetric methods—Pharm., —
J. 1916, v. 97, p. 571,
229
MENTHA PIPERITA.
van der Wielen: Notes on the cultivation of Mentha piperila in
Holland. Mentha piperita is stated to be a hybrid of Jf. aquatica
and MW. viridis —Chem. & Drug. 1916, v. 88, p. 911.
MENTHOL.
_ Anon.: The new edition of the Finnish pharmacopeeia specifies
that menthol shall melt at 43° to 44° C.—Am. Perf. 1916, v. 11, p. 94.
_ Likhatcheva, N. P.: The action of camphor and menthol on coro-
nary and peripheral vessels. The author found from her experi-
ments on the ear and heart of rabbits that camphor, borneo}, and
menthol dilate the coronary. peripheral blood vessels in dilutions of
#:2500 and 1:5000. An abstract—J. Am. M. Assoe. 1916, v. 67,
. 843 from Russkiy Vrach, 1916, v. 15, No. 21.
METHYLIS SALICYLAS.
Scoville, Wilbur L.: The main advantage of the U. S. P. IX
specifications for methyl salicylate is that one can now properly
“label a drug as “Oil of Wintergreen, True,” “Oil of Wintergreen,
from Sweet Birch,” or “Oil of Wintergreen, Synthetic,” as the case
may be.—Bull. Pharm. 1916, v. 30, p. 364.
_ Umney, J. C.: The specific gravity for natural wintergreen oils
(1.175 to 1.182 at 25° ©.) is very properly placed lower than that
for the synthetic methyl salicylate (1.80 to 1.185 at 25° C.).—Perf. &
‘Ess. Oil Ree. 1916, v. 7, p. 344.
_ Leone, Gustavo: A report of experimental researches to determine
the toxic action of methyl salicylate. The most striking effects in
dogs are found to be an intense hyperemia of the brain and lungs.—
Arch. farmacol. sper. 1916, v. 22, p. 327-352.
METHYLTHIONINZ CHLORIDUM.
Reberts, J. G.: A sample from one lot of methylene blue examined
had an abnormal purplish-brown color, contained zinc, and yielded
21.87 per cent residue upon ignition.—Proc. Pennsylvania Pharm.
pAssoc. 1916, p. 114.
Scoville, W. L.: Many lots of methylene blue examined contained
bzinc.—J. Am. Pharm. Assoc. 1916, v. 5, p. 541.
Swift, E. G.: One sample of methylene blue examined yielded
49.6 per cent of ash.—Oil, Paint & Drug Rep. 1916, v. 90, No. 16,
p. 46. . |
MISTURA CRETZ.
_ Anon.: Notes on the preparation of chalk mixture.—N. A. R. D. J.
1916, v. 22, p. 428,
) 110095°—19—15
226
MISTURA GLYCYRRHIZE COMPOSITA.
Anon.: Detailed directions for the preparation of the compound
mixture of elycyrrhiza are given—wN. A. R. D. J. 1916, v. 21, p. 660.
MISTURA OPIii ET RHEI COMPOSITA.
Raubenheimer, Otto: The history of the origin of “Sun Cholera
Mixture.”—J. Am. Pharm. Assoc. 1916, v. 5, p. 624-625; see also Nat.
Druggist, 1916, v. 46, p. 279-280.
Raubenheimer, Otte: A reconstructed formula for sun cholera
mixture is presented. The formuia contains 50 per cent of paregoric
instead of 20 per cent of tincture of opium.—ZJ. Am. Pharm. Assoc,
1916, v. 5, p. 840.
MISTURA PECTORALIS, STOKES, N. F.
Anon.: The official title for this preparation is a most violent af-
front to proper nomenclature and ethics in spite of the fact that the
principles of revision intended to pei therapeutic and ana-
tomical titles —N. A. R. D. J. 1916, v. 22, p. 1082.
MORPHINA.
Von Braun, J.: Researches on the chemistry of morphine deriva-
tives—Chem. Zentralbl. 1916, v. 87, part 2, p. 17-19.
Carlinfanti, E.: Descriptions of color mere methods for the deter-
mination of minute quantities of morphine and codeine. The red
color produced by the addition of concentrated sulphuric acid with a
trace of nitric acid is the basis for the estimation of morphine.—
Chem. Abstr. 1916, v. 10, p. 1909.
Debourdeaux: Notes on the quantitative determination of mor-
phine in galenical preparations. The author calls attention to the
fact that the presence of alcohol, starch, and other substances in- 7
fluence the correctness of the results obtained with the lime method.
Hie also states that temperature errors are the lowest between 15°
and 18° C. An abstract.—C. U. C. P. Alumni J. 1916, v. 23, p. 202%
Tunmann, O.: Descriptions of microchemical methods for dis-
tinguishing between morphine and ec J. Chem. Soc. Lond.
1916, v. 110, part 2, p. 655-656 from Apoth.—Ztg. 1916, v. 31, p. 148-_
150.
Doran, James M.: A description of a method for the separation of
morphine and heroin in which the latter is removed from the alka-
line liquid by means of carbon tetrachloride. Morphine is soluble to
a very shght ext arm. Assoc. 1916, v. 5, p. i63—
165; see also Chem. Abs 1916, 10, p. 1406.
227
-Homberger, A. W., and Munch, J. C.: A report of investigations
relating to the quantitative determination of morphine in the various
organs when injected into cats and rabbits—J. Am. Chem. Soe.
1916, y. 38, p. 1873-1876.
~ Rosenbaum, Nathan: Form experiments, it is concluded that dily-
dromorphine and diacetyldihydromorphine when used subcutaneously
re satisfactory substitutes for morphine as they do not appear to
produce addiction. An abstract——Chem. Zentralbl. 1916, v. 87, Part
2, p. 159.
Editorial: A review of some of the recent articles dealing with the
‘subject of acquired tolerance to morphine.—J. Am. M. Assoc. 1916,
y. 66, p. 657.
Editorial: A discussion of the need for making a careful examina-
tion of the morphine habitué before he is subjected to the with-
drawal of the drug or to the severe treatment that is necessary to pro-
mote that object—.J. Am. M. Assoc. 1916, v. 66, p. 190.
Heimann, Bertha: A report of pharmacological investigations
relative to the toxicity of various derivatives of morphine and co-
-deine—Chem. Zentralbl]. 1916, v. 87, part 1, p. 1169.
Macht, David I.: A report of researches to determine the compara-
tive toxicity of morphine and morphine-narcotine (nareophine).—
“Am. J. M. Se. 1916, v. 152, p. 16-27.
Anon.: A report of a case of central scotoma following the use of
“habitina,” a nostrum containing 16 grains of morphine and 8 grains
of heroin to the ounce.—J. Am. M. Assoc. 1916, v. 66, p. 978.
Beates, Henry, jr.: A report of a case of recovery from profound
morphine poisoning.—Med. Council, 1916, v. 21, p. 50-51.
Kleiner, I. S., and Meltzer, S. J.: A report of experiments to deter-
mine the influence of morphine on the elimination of intravenously
injected dextrose.—Proc. Soc. Exper. Biol. & Med. 1916, v. 13, p.
142-143.
Skeel, Arthur J.: Analgesia and anesthesia in obstetric practice. A
review of the principal theoretical considerations obtaining to the
use of morphine.—J. Am. Assoc. 1916, v. 66, p. 797-799.
~ Coburn, Raymond C.: Morphine as a preliminary medication in
nitrous oxide administration tends to allay preoperative fear and
renders the induction smoother.—J. Am. M. Assoc. 1916, v. 66, p. 800.
Davis, Benjamin F.: The relation of morphine to postoperative
complications and immunity.—J. Am. M. Assoc. 1916, v. 66, p. 252-
(255.
Editorial: The behavior of the uterus and other organs toward
‘morphine and scopolamine. A review of several recent papers.—J.
Am. M. Assoc. 1916, v. 66, p. 577-078.
228
MORPHINZ HYDROCHLORIDUM.
Francois, M., and Luce, E.: A description of tests for the identity
and purity of morphine hydrochloride and of a method for the
quantitative determination of the same in standard solutions, syrup
of morphine hydrochloride and similar preparations.—J. pharm, et
chim. 1916, v. 13, p. 145-155.
MOSCHUS.
Anon.: Notes on the loss in weight of musk on keeping. C. B.
Bazzoni found that musk lost 14 per cent of its weight in seven
months. It also lost its odor, which could not be restored by crush-
ing, moistening, or exposure to the air. An abstract.—Sci. Am. 1916,
pr ats:
Anon.: Notes on odors, principally of musk, and the attempts made
to find a synthetic substitute-—Perf. & Ess. Oil Rec. 1916, v. 7, p.
133-134.
MUCILAGO TRAGACANTHZES.
Anon.: It is suggested that spirit of chloroform be substituted
for the alcohol in the official English formula. The preparation
would then keep better—Chem. & Drug. 1916, v. 88, p. 102.
MYRICA, N. F.
Anon.: A short note giving information relative to the production
and collection of bayberry bark in America—N. A. R. D. J. 1916,
Veo21 pit. |
MYRISTICA.
Anon.: A note on the history of nutmeg and mace.—Perf. & Ess.
Oil Rec. 1916, v. 7, p. 76-77. =
Frary, Guy G.: All of the samples of nutmeg and mace examined —
were passed.—Rep. South Dakota F. & D. Com. 1916, No. 16, p. 135-
36,
MYRRHA.
Rusby, H. H.: Several lots of myrrh examined contained many
dark, soft, and sticky pieces of peculiar, intense, bitter taste. It has —
been maintained that this is genuine myrrh. If so, the U. S. P.
description should be so changed as to include them.—J. Am. Pharm.
Assoc, 1916, v. 5, p. 541.
E’we, G. E.: Only two of seven lots of myrrh examined met the
U.S. P. EX requirement of 35 per cent alcohol solubility. The other —
five lots ran 24.6, 27.0, 30.1, 30.4, and 33.9 per cent, respectively.—
Proc. Pennsylvania Pharm. Assoc. 1916, p. 115.
229
Roberts, J. G.: One sample of myrrh examined proved to be of
inferior quality on account of containing only 25 per cent of aleohol-
soluble matter and yielding 14.7 per cent of ash—Proc. Pennsyl-
vania Pharm. Assoc. 1916, p. 115.
NAPHTHALENUM.
Tiilpert, S.: Data showing the solubility of naphthalene in pure
NH, and in aqueous ammonia solutions of different str engths. In 10
per cent solution of ammonia, it is soluble to the extent of 0.042
gram per 1,000 grams. The solubility is influenced by the presence
of pyridine. An abstract—Pharm. J. 1916, v. 96, p. 521.
Roberts, J. G.: One lot of naphthalene examined was rejected on
account of its oily condition which rendered it unfit for use as a
moth preventive—Proc. Pennsylvania Pharm. Assoc. 1916, p. 115.
NITROGENII MONOXIDUM.
Baldwin, J. F.: An article calling attention to the dangers en-
countered in producing anesthesia with nitrous oxide-—Med. Ree.
1916, v. 90, p. 177-180.
MecCardie, W. J.: A report of a case of death after the use of
nitrous oxide-oxygen for the production of local anesthesia—Brit.
eared, vy. 2p. 109.
Robinson, William E.: A report of a death after nitrous oxide-
oxygen in spinal anesthesia.—Brit. M. J. 1916, v. 2, p. 291-292.
Jackson, D. E.: A report of researches to determine the pharma-
cologic action of nitrous oxide—QJ. Lab. & Clin. Med. 1916, v. 1,
p. 644-661.
Crile, George W.: A report of experimental researches to deter-
mine the nature of nitrous oxide and of ether anesthesia.—J. Am.
M. Assoc. 1916, v. 67, p. 1830-1831.
' Cooke, A. B.: The ideal anesthetic for major surgery is the one
capable of producing analgesia and unconsciousness without danger
of discomfort to the patient. Any agent or method which furthers
‘this ideal—which tends in any way to relieve surgery of its harsh-
ness and to smooth down the rough places—should receive our most
earnest and open-minded attention. My experience with nitrous
oxide as an anesthetic would seem to warrant the conclusion that it
is entitled to high rank in this beneficent class—J. Am. M. Assoc.
1916, v. 67, p. 175-177.
MeCar mick, A. S.: Nitrous oxide will usually anesthetize a patient
more quickly than ether; but once in six to ten times the addition or
‘substitution of the latter is necessary.—J. Am. M. Assoc. 1916, v. 66,
No. 1, p. 49
230
Soule. W. L.: Nitrous oxide versus ether. Following nitrous exid
anesthesia, vomiting takes place in a proportion of cases by no means
jsieeee ast even when the anesthesia has been satisfactory and no
i required.—J. Am. M. Assoc. 1916, v. 66, p. 376.
Coburn, Raymond C.: Notes on nitrous oxide administration.
Even with the accumulated knowledge gained from several years’
experience in the prolonged administration of nitrous oxide (and
oxygen), there is still quite a tendency by some to disregard essen-
tial elements of safety, especially when nitrous oxide, administered
with normal oxygenation, does not furnish a sufficient depth of
anesthesia.—J. Am. M. Assoc. 1916, vy. 66, p. 799-800.
Heaney, N. S.: A discussion of the employment of nitrous oxide
analgesia in obstetrics.—Med. Rec. 1916, v. 89, p. 995-997; see also
A. J. Skeel, J. Am. M. Assoc. 1916, v. 66, p. 797-799, and F. C. Irving,
Boston M. & 8. J. 1916, v. 174, p. 462-464.
NUX VOMICA.
Memminger, Lucien: A consular report describes the collection
and exportation of nux vomica in Madras Presidency.—Com. Rep.
1916, No. 217, p. 1012; see also Am. Food J. 1916, v. 11, p. 505.
Kensen, H. R.: Experimental data relative to the determination
of strychnine in nux vomica. The process of the Ph. Brit. 1914
gives low results because nitration is directed to be carried out at
50° C. instead of 20° C.—Pharm. J. 1916, v. 97, p. 488-461.
Watt, H. E., and Angus, G. B.: Nux vomica contains 1 to 2 per
cent of a solid fat consisting principally of the glycerides of capric, —
caprylic, caproic, butyric, and palmitic acids. The chemical and —
physical constants of the fat are also given.—J. Soc. Chem. Ind.
1916, v: 35,.p..201.
K’we, G. E.: Of 16 samples of nux vomica assayed, the strychnine
content of 2 was above standard and 14 below.—Proc. Pennsyl-
vania Pharm. Assec. 1916, p. 119.
Patch, EK. L.: Five samples of nux vomica examined assayed 1.175,
1.195, 1.115, 1.155, and 1.25 per cent, respectively, of strychnine.—
J. Am. Pharm. Assoc. 1916, v. 5, p. 541.
Vanderkleed, C. E.: The strychnine content of seven lots of nux
vomica examined ranged between 0.705 and 1.828 per cent. The
average was 1.013 per cent.—J. Am. Pharm. Assoc. 1916, v. 5, p. 541.
OLEA PINGUA.
Rabak, Frank: The utilization of cherry by-products, including a —
description of a method for extracting the oil from the pits.—U. S.
Dept. of Agric. Bull. 1916, No. 350, p. 1-24. ~
7 a
231
_ Alpers, K.: An account of the extraction of fatty oils in Germany
from the kernels of stone fruits. An abstract.—Pharm. Weekblad,
1916, v. 53, p. 1618.
Baskerville, Charles: A description of a new process for the re-
| fining of vegetable oils.—J. Ind. & Eng. Chem. 1916, v. 8, p. 118-120;
J. Franklin Institute, 1916, v. 181, p. 733-746.
Schrauth, W.: A discussion of the use of fats in the preparation
of synthetic remedies.—Chem. Abstr. 1916, v. 10, p. 1905 from Seifen-
fabr. 1916, v. 36, p. 217-221.
_ Slack, H. F.: A short account of the early and modern processes
' of fat splitting —Perf. & Ess. Oil Rec. 1916, v. 7, p. 221-223.
Rudd, W. F.: The paper presents results of experiments relating
| to the hydrolysis of several vegetable oils. One of the objects of
these investigations was to determine if the relative saponification
| factor is an indication of the relative digestibility of the oils—J. Am.
Pharm. Assoc. 1916, v. 5, p. 170-174.
Backer, H. J.: A discussion of the relationship between the physi-
eal and chemical constants of the fixed oils and fats, illustrated with
a number of tables containing data of this nature-—Chem. Week-
blad, 1916, v. 13, p. 954-967.
Editorial: A review of some of the literature on the scientific
aspect of the phenomenon of “ drying” possessed by certain fixed
ouls.—Nature, 1916, v. 97,-p. 269-270.
Pigulevski, G.: Observations on the variation in the composi-
tion of fixed oils of plants of the same family.—J. pharm. et chim.
1916, v. 13, p. 258 from J. Russ. Chem. Soe. 1915, v. 47, p. 393.
Gardner, Henry A.: Data showing the storage changes in vegetable
and animal oils.—J. Ind. & Eng. Chem. 1916, v. 8, p. 997-998.
Smith, H. L.: A discussion of the chemical and biological factors
which influence the development of rancidity in fats. Directions
are also given for protecting fats from this change and for partly
removing the unpleasant odor after rancidity has developed.—
Pharm. J. 1916, v. 41, p. 4.
Scoville, Wilbur L.: The odor of rancid fats may be removed
with a solution of potassium permanganate. Excessive amounts of
free acid are best removed by shaking with sodium silicate solu-
tion.— Bull. Pharm. 1916, v. 30, p. 78.
Vintilescu, J., and Popescu, Alin: Biochemical reactions of rancid
fats. Free oxygen is liberated by the addition of one of the peroxi-
dases. The guaiac test can then be applied—Apoth.-Ztg. 1916, v.
31, p. 42.
Issoglis, G.: A description of a new method for the determination
of the degree of rancidity of fats. The author proposes to de-
termine the “ oxidizability number.” This refers to the number of
232
wailligrams of oxygen required to oxidize the material obtained in
the steam distillation of 100 grams of fat or oil. An abstract.—
Cc. U. C. P. Alumni J. 1916, v. 23, p. 231.
van Leent, F. H.: A detailed discussion of information relative
to the hardening of fats and the chemical and physical properties
of hardened fats—Chem. Weekblad, 1916, v. 13, p. 712-770; see also
Pharm. Weekblad, 1916, v. 58, p. 725-769; C. A. Pekelharing and
W. Schut, p. 769-785.
Wright, C. H.: Notes on the determination of the specific gravity
of fixed oils in the Tropics.—J. Soc. Chem. Ind. 1916, v. 35, p.
457-458.
Romarnelli, R.: An illustrated description of a new method for —
determining the melting point of fats—Chem. Abstr. 1916, v. 10, p.
284 from Farmaceutisk. Revy, 1915, p. 28.
Monhaupt, M.: A description of a new method for determin-
ing the melting point of fats—J. Sec. Chem. Ind. 1916; v. 89, p. 971
from Chem.-Ztg. 1916, v. 40, p. 676.
Hackmann, C. A.: Experiments with the Rose-Gottheb method
fer the determination of fats in pharmaceutical preparations.—
Chem. & Drug. 1916, v. 87, p. 19.
Holland, E. B., Reed, J. C., and Buckley, J. P.: Descriptions of
the improved methods for the analysis of fats—Chem. Abstr. 1916,
10, p. 1941 from Bull. Massachusetts Agric. Exper. Sta. 1915,
No. 166, p. 91-188.
van Kregten, J. R. N.: A description of a simple colorimeter for
determining the purity of oils—Chem. Weekblad, 1916, v. 13, p.
1157-1159.
Sixley and Frehse: A new color reaction for vegetable oils is ob-
tained when 10 mils of a vegetable oil are mixed with 5 mils of a 20
per cent sodium acetate solution and a few drops of diazotized para-
nitroaniline solution. An abstract—Drug. Cire. 1916, v. 60, p. 275.
Francois, Maurice: Researches on the identification of fats by
means of rosaniline bisulphite. The article also includes an attempt-
ed explanation of the color changes produced in the action of this
reagent upon aldehydes.—J. pharm. et chim. 1916, v. 13, p. 65-77;
Ann. Falsif. 1916, v. 9, p. 74-88; Farm. Espa. 1916, v. 48, p. 551—
553, 567-569, 583-585.
Mazzaron, A.: A description of a new and sensitive method for
the identification of fatty oils. The method is based on the deter-
mination of sulphur dioxide liberated when 20 cubic centimeters of
the oil are treated with 5 cubic centimeters of concentrated sulphurie
acid. An abstract—Ann. Falsif. 1916, v. 9, p. 100.
Bull, H.: A description of a method for the estimation of glycerol
in oils as sodium glyceroxide.—Chem.-Ztg. 1916, v. 40, p. 690 through:
Analyst (The), 1916, v. 41, p. 343.
293
- Marcusson, J., anAS von Huber, H.: A report of investigations
dealing with the detection of marine animal oils in oils, fats, and
soaps. An abstract.—C. U. C: P. Alumni J. 1916, v. 23, p. 250.
Gruen and Janks: A description of a HOUIGSE Fortelli-Jaffe
method for the detection of fish oils. An abstract.—Drug. Cire.
1916, v. 60, p. 145. .
Stadalin, W.: A report of investigations relating to the deter-
mination of benzoic acid in fats.—Chem.-Ztg. 1916, v. 40, p. 770; J.
Sec. Chem. Ind. 1916, v. 35, p. 1128.
Kerr, Robert H.: A description of an improved method for the
detection of arachidic acid in peanut oil and mixtures of oils con-
taining pes g. Chem. 1916, v. 8, p. 904.
Marden, J. W.: A report of spores to determine the heat of
bromination of fats and oils.—J. Ind. & Eng. Chem. 1916, v. 8, p.
421-126,
Pfeffer, Otto: ees on the detection of epee and cholesterol
by means of digitonin——Physiol. Abstr. 1916, v. 1, p. 384 from
Ztschr. Unters. Nahr.- u. Genussm. 1916, v. 31, +s 3840,
Uchida, S.: Information concerning the physical characters and
chemical constituents of a number of oils-is given.—J. Soc. Chem.
Ind. 1916, v. 35, p. 1089.
Bray, G. T., and Elliott, F. L.: A presentation of analytical data
relating to some new oil seeds derived from American palms.—
Analyst (The), 1916, v. 41, p. 298-802.
Browne, Frank: Data relating to the physical constants of China
wood oil. The bearing of these constants on the examination of the
oil are discussed. —Chem. News, 1916, v. 114, p. 128.
Bacon, Chas. V.: Tables showing the physical and chemical con-
tents of tea-seed (camellia theifera) oil ave presented.—Oil, Paint &
Drug Rep. 1916, v. 90, No. 21, p. 51.
Fachini, S., and Dorpa, G.: A chemical study of the oil of the
fruits of Parthenocissus guinquefolia, Planchon.—Ann. chim. appli-
cata. 1916, v. 5, p. 501-304.
OLEUM AMYGDALZ EXPRESSUM.
Wastenson, H.:; Notes on the testing of almond oil, accompanied
by analytical data obtained in the examination of a number of sam-
ples. Changes in the Ph. Svec. method % Svensk
- farm. Tidsskr. 1916, v. 20, p. 256-261.
Roberts, J. G.: One sample of oil of sw ect almond examined was
rejected on account of having an iodine number of 106. The U.S. P.
standard is not above 100.—Proe. Pennsylvania Pharm. Assoc. 1916,
ep. 116.
234
Tice, William G.: Of two samples of oil of sweet almond exam-
ined, one was below standard.—Rep. New Jersey Dept. Health, 1
p- 72,
OIL, CHAULMCOGRA (NONOFFICIAL).
Rakuzin and Flier: From a comparison of the available literature
on chaulmoogra oils, it is concluded that Olewm Chaulmoogre and
Oleum Gynocardie are not identical, and that only the optically ac-
tive chaulmoogra oil and chaulmoogric acid are of medicinal yalue.—
Drug. Cire. 1916, v. 60, p. 750.
Brill, H. C.: In a paper discussing the source of the false varie-—
ties of chaulmoogra oil, the author states that toraktogenos and —
hydnocarpus oils are Eee identical, but that the oil from
Gynocardia odorata may be different—Philippine J. Se. 1916, yv.
11, see. A, p. 75-80.
Anon.: The intravenous injection of a sterilized emulsion of chaul-
moogra oil is stated to have given encouraging results in the treat-
ment of leprosy.—Chem. & Drug. 1916, v. 88, p. 69.
Anon.: A lst of references to articles on the use of chaulmoogra
oil in the treatment of leprosy.—J. Am. M. Assoc. 1916, vy. 66,
p- 1576.
Brill, H. C.: Data obtained in the examination of the oil from the
seeds of Hydnocarpus venenata, false chaulmoogra.—Philippine J.
Se: 1916. sec. Avy. 11, ph ia:
Rogers, Sir Leonard: A report on the preparation of sodium
gynocardate and its use in the treatment of leprosy.—Brit. M. J.
1916, v. 2, p. 550-552.
OLEUM GOSSYPII SEMINIS.
Utz: From experiments, it is concluded that Beechi’s reaction is
retarded and that Halphen’s test is negative when applied to cotton
seed oil which has been bleached with benzoyl peroxide. An ab-
stract—Drug. Cire. 1916, v. 60, p. 211.
Besson, A.: The author reports on the application of the Millian
test to the detection of kapok oil in cotton seed oil. An abstract.—
C.U, C; P. Alumni J. 1916, v. 282 p12:
} OLEUM LINI.
Seaton, Max Y., and Sawyer, G. B.: Data showing the molecular
weight of linseed oil as determined by the freezing-point. boiling-—
point, and stearic-acid methods.—J. Ind. & Eng. Chem. 1916, y. 8, p.
490-493,
235
Salway, Arthur H.: Studies on the oxidation of unsaturated fatty
oils and unsaturated fatty acids. Part I. The formation of acrolein
by the oxidation of linseed oil and linolenic acid.—J. Chem. Soe.
Lond. 1916, v. 109, p. 138-145.
Table showing some of the analytical resulls reported for linseed oil.
Number of samples— |
Reporters. References.
Examined.) Rejected. |
Cin yi iS 7 12 | Bull. Indiana Bd. Health, 1916, v. 19, p. 15, 52,
4s 76, 112.
TSE MOS ae u 8} Bull. Michigan D. & F. Dept. 1916, No. 252-255,
| pe do:
Congdon, Teon"A...........-- 6- 1 | men Kansas Bd. Health, 1916, p. 133.
Howard, Charles D.........-- 2 1} Bull. New Hampshire Bd. Health, 1916 v. 4,
j : | Nos. 7-8, p. 129.
LAE et Net 5 3) pele Se eee 210 20 | Bull. Lab. Inl. Rev. Pept., Canada, 1916, No.
332, p. 5
“SUI, Ub 10s ee 2 1 | Bull. Kansas Bd. Health, 1916, p. 13.
OLEUM MORRHUZ.
Chapman, A. C.: A report on the presence of a new hydrocarbon
(C.,H,;,) in a sample of cod liver oil examined. The author calls it
spinacidene, as it has been obtained from the livers of certain mem-
bers of the subfamily Spinacida.—Chem. &. Drug. 1916, v. 88, p. 1242.
Neno, Seuchi: Kombara earth (an acid soil) is stated to be a
good reagent for the identification of cod liver cil. A bluish-green
color is produced when a small amount of the oil is shaken with about
1 gram of the earth.—Boll. chim.-farm. 1916, v. 55, p. 11.
Mastbaum, H.: A shipment of fish oils received in London was
condemned for being adulterated with mineral oil. Upon examina-
tion the oil proved to be that obtained from the livers of certain
Mediterranean fish. These oils are stated to contain 80 to 90 per
cent of unsaponifiable hydrocarbons having the properties of mineral
‘ou. Pharm. J. 1916, v. 96, p. 327.
Swift, E. G.: It is difficult to secure cod liver oil of satisfactory
quality. Most of the supplies are dark in color and unpleasant in
taste.—Oil, Paint & Drug Rep. 1916, v. 90, No. 16, p. 46.
Roberts, J. G.: Three lots of cod liver oil examined gave saponifica-
tion numbers above the U. S. P. maximum of 185. As they were
within the limits of 180 to 190 adopted for the U. S. P. TX, they
were considered to be of desirable quality—Proc. Pennsylvania
Pharm. Assoc. 1916, p. 11.
OLEUM OLIV.
Parry, Ernest J.: In normal times, the most common adulterant
Af olive oil is arachis oil. The U. S. P. gives color reactions for
cotton sced oil and sesame oil, but the perfectly reliable method of
—
236
detecting and approximately estimating arachis oil is not even re-
ferred to. This is incredible in a pharmacopeeia published in 1916.—
Chem. & Drug. 1916, v. 88, No. 1913, p. 40.
Parry, Ernest J.: The validity of prescribing Becchi’s test for cot-—
ton seed oil in the case of lard and Halphen’s test in the case of olive
oil is questioned.—Chem. & Drug. 1916, v. 88, No. 1913, p. 40.
Biazzo, R., and Vigdorcik, Se.: A review of methods for the de-
tection of peanut oi] in olive oil, with a description of a new
method.—Ann. chim. applicata. 1916, v. 6, p. 179-185.
Biazzo, R., and Vigdorcik, S.: A description of a method for the
detection of rapeseed oil in olive oil—Ann. chim. applicata. 1916,
v. 6, p. 185-195.
Lea, E. J.: Many druggists in this State are still dispensing cot-
ton seed oil for sweet oil.— Bull. California Bd. Health, 1916, v. 12,
p- 00.
Lea, E. J.: Samples of olive oil examined contained rancid oi! and
had the odor of decayed vegetable material—Bull. California Bd.
Health, 1917, v. 12, p. 280.
Roberts, J. G.: One sample of olive oil was rejected on account of
having an acid number of 4.21, which is too high for an edible oil.—
Proc. Pennsylvania Pharm. Assoc. 1916, p. 116.
Anon.: Of 58 samples of olive oil analyzed, 10 were rejected —Rep.
Utah D. & F. Com. 1916, p. 96.
Lythgoe, Hermann C.: Of 30 samples of olive oil examined, three
were adulterated.—Rep. Massachusetts Bd. Health, 1916, p. 450.
Todd, A. R.: One sample of olive oil examined was rejected.—Bull.
Michigan D. & F. Dept. 1916, No. 250-251, p. 16.
OLEUM RICINI.
Lemberger, Joseph L.: A short article on the possibility of culti-
vating the castor oi] plant on a scale sufficiently large for commercial
purposes.—J. Am. Pharm. Assoc. 1916, v. 5, p. 737-739.
Memminger, Lucien: A consular report on the castor oil industry
of India—Com. Rep. 1916, No. 228, p. 1187-1188.
Anon.: A description of a method for rendering resinified castor
oil fluid—Schweiz, Apoth.-Ztg. 1916, v. 54, p. 598 from Pharm. Ztg.
1916, v. 61, p. 356.
Anon.: Notes on the early history of the use of castor oil in thera-
peutics.—Chem. & Drug. 1916, v. 88, No. 1877, p. 47.
Lea, E. J.: A sample of castor oil examined was adulterated with
peanut oil and sperm oi].—Bull. Califorina Bd. Health, 1916, y. 11, —
p. 536,
Frary, Guy G.: A sample labeled “ Eldorado castor oil” was mis-
branded as it contained no castor oil but consisted largely of mineral
237
oil admixed with 7 per cent of fatty oils—Rep. South Dakota F. &
. Com. 1916, No. 16, p. 151.
OLEUM SESAMI.
Senft, Eman.: Notes on the cultivation of Sesamum indicum
'D. C.—Pharm. Post, 1916, v. 41, p. 87-89.
OLEUM TIGLII.
Comte: Descriptions of a colorimetric and a physiologic method
for identifying small quantities of croton oil—QJ. pharm. et chim.
1916, v. 14, p. 38-39.
~ Boehm, R.: A neutral substance which on further purification
yielded croton resin was separated from crotonolic acid. This resin
was found to be extremely poisonous to frogs. An abstract.—
‘Pharm. Zig. 1916, v. 61, p. 116.
OLEA VOLATILA.
Anon.: A summary of the general results of the 1914 census of
manufactures for the essential oil industry issued by Director
Samuel L. Rogers of the Bureau of Census, Department of Com-
merce.—Northwestern Druggist (The), 1916, v. 17, No. 8, p. 31.
Adrian, J. L.: An illustrated description of an up-to-date oil
distillery in Spain.—Perf. & Ess. Oil Rec. 1916, v. 7, p. 44-45.
Editorial: Remarks on the application of science to the culti-
vation of perfume plants.—Perf. & Ess. Oil Ree. 1916, v. 7, p. 31-82.
Parry, E. J.: Criticisms of the U. 8. P. IX monographs on essen-
tial oils. Special objection is made to the frequent omission of fig-
ures for refractive index and rotatory power.—Perf. & Ess. Oil Ree.
1916, v. 7, p. 296-802.
Editorial: An English criticism of the new edition of the U.S. P.
_ealls attention to the fact that only in a few cases are tests prescribed
for the neutrality or slight acidity of alcoholic solutions of the vola-
tile oils. The reason for this lack of uniformity in tests is not under-
stood.—Chem. & Drug. 1916, v. 88, No. 1921, p. 49.
Anon.: A synopsis of Schimmel & Co.’s criticism of the essential
oil monographs of the British Pharmacopeeia.—Chem, & Drug. 1916,
yv. 88, No. 1877, p. 52.
Anon.: No solubility data are given in the Ph. Brit. for the oils
of cajuput, Siberian fir, ajowan, copaiba, cubeb, lemon-grass, rose,
mustard, and rectified turpentine. The omission is condemned on
“pharmaceutical grounds.—Chem. & Drug. 1916, v. 88, p. 793.
- Amon.: A review of the third volume of the second edition of
Gildemeister’s Essential Oils states that there is little new work in
238
the book, which is, in fact, a compilation of the work that has ap-
peared since the a et ee! —Chem. & Drug. 1916, v. 88, No. 1925,
Dp: 3. ‘4
Anon.: A dictionary of essential oils, with bibliographic refer-
ences and index to common names.—Perf. & Ess. Oil Ree. 1916, v. 7,
p- 152-206. :
Reclairve, A.: A review of the a de in the is of the
terpenes and the essential oils for the ve
Ztg. 1916, v. 40, p. 977-978, 987-989, 1000- 1001, 1019- 1022,
Editorial: Observations on the oe of esenel oil research.—
Perf. & Ess. Oil Rec. 1916, v. 7, p. 3-4.
Parry, Ernest J.: Suggestions relative to any attempts at the
scientific classification of odors.—Perf. & Ess. Oil Ree. 1916, v. 7,
p. 129-122. |
Dupont, Justin: A classification of synthetic products used in the
manufacture of synthetic: perfumes.—Scientific American, 1916,
No. 2108.
Prins, H. J., and Schwarz, S.: An enumeration of the different
esters present in essential oils and a discussion of their use in the —
manutacture of perfumery.—Perf. & Ess. Oil Rec. 1916, v. 7,
p. 334-839.
Swift, E. G.: Artificial substitutes for the natural volatile oils are
increasing. Oils of coriander, rose, neroli, and cinnamon (Ceylon)
are mostly of the artificial variety. It is needless to say that they are
not as satisfactory as the natural oils, but the latter are not always
obtainable.—Oil, Paint & Drug Rep. 1916, v. 90, No. 16, p. 46.
Cusmano, Guido: A discussion of the processes of oxidation and —
reduction in the terpene group.—Gaz. Chim. Ital. 1916, v. 46,
p. 281-289.
Bonis, A.: A report of investigations bearing on the quantitative
determination of volatile oils in liquers—Ann. Falsif. 1916, v. 9,
p- 12-14; see also L. Bonnet, p. 14-16; C. F. Muttelet, p. 17-22,
70-73; and X. Rocques, p. 127-143.
Woodman, A. G., et al.: A description of a nephelometric methed
for the determination of small amounts of essential oils.—J. Ind.
& Eng. Chem. 1916, v. 8, p. 128-131.
Anon.: A criticism of a recent publication by T. H. Durrans on
the analysis of essential oils—Perf. & Ess. Oil Ree. 1916, v. 7,
p. 219-220.
Anon.: A note on the use of vanillin hydrochloride as a reagent
for the identification of volatile oils. An abstract—Ann. Falsif.
1916, v. 9, p. 480. |
Anon.: A discussion of “optics” as applied te the analysi’ of ©
volatile oils—Perf, & Ess. Oil Rec. 1916, v. 7, p. 65-67. .
_ Marcille, R.: A report of rescarches relative to the determination
of the iodine index of volatile oils, with special reference to the in-
fluence of luminosity.—Ann. Falsif. 1916, v. 9, p. 6-11.
Anon.: In the acetylation process for the estimation of alcohols in
essential oils, the acetic anhydride employed should have a speci-
fic gravity of at least 1.080 and should contain not less than 95 per
cent of acetic anhydride. It is also necessary to be certain of the
absence of moisture in-the anhydrous sodium acetate used.—Pert.
& Ess. Oil Rec. 1916, v. 7, p. 374.
Simmons, W. H.: A discussion of the use of formic acid for de-
termining relative amounts of perfume alcohols in volatile oils.
The author concludes that formic acid is a valuable reagent for use
in the examination of the oils of geranium, rosemary, and pepper-
-mint.—Analyst, 1916, v. 40, p. 491-494.
Slack, H. I’.: A description of a new method for determining aci:l
and ester values. Commercial benzyl alcohol is employed as the
solvent for the oil—Chem. & Drug: 1916, v. 87, p. 673.
Anon.: Remarks on the value of fractional distillation in the de-
tection of adulterations in essential oils—PDPerf. & Ess. Oil Rec. 1916,
v. 7, p. 250-252.
Anon.: Remarks by Christian Beilstein on the sophistication of
essential oils—Perf. & Ess. Oil Rec. 1916, v. T, p. 371.
Anon.: American peppermint and sandalwood oils are cited as
examples to show that essential oils may be adulterated in such a
way that it is impossible to detect sophistication without fractional
distillation and the examination of each fraction —Perf. & Ess. Oil
Ree. 1916, v. 7, p. 249.
E’we, G.: Notes on the market quality of some vclatile oils used in
veterinary practice namely, the oils of cajeput, chenopodium, juni-
per, origanum, peppermint, sassafras, and turpentine.—Mulford’s
Vet. Bull. 1916, v. 7, p. 139-141.
Scoville, W. L.: The difficulties experienced at present in the im-
portation ef volatile oils has led to some attempts at adulteration.
The mixing of natural and synthetic products seems to have in-
creased, and it is difficult to obtain some oils of satisfactory quality.
Oil of rose geranium, oil of eucalyptus, and oil of neroli are examples
of this class.—J. Am. Pharm. Assoc. 1916, v. 5, p. 541.
Anon.: A note on the sweetening value of volatile oils, including
oils of cinnamon, phenyl, and anise.—Perf. & Ess. Oil Ree. 1916,
1, p. 62.
Editorial: Notes on the use of volatile oils for the destruction of
-vermin.—Perf. & Ess. Oil Rec. 1916, v. 7, p. 4-0.
Muirhead, A. L. and Geraldn, H. F.: A study of the action of
certain volatile oils on irrigated intestinal segments. The oils used
240
were pennyroyal, tansy, wormwood, turpentine, rue, anise, and sa-
vine.—J. Pharmacol. & Exper. Therap. 1916, v. 8, p. 253-260.
Anon.: Descriptions of the physical and chemical properties of a
number of little known essential oils—Perf. & Ess. Oil Rec. 1916,
v. 7, p. 839-340.
Uchida, S.: Descriptions of the characteristics and constituents of
a number of Japanese essential oils are given.—Cher. & Drug. 1916,
y. 88, p. 476.
Umney, J. C.: A presentation of data showing the difference be-
tween Bourbon and Algerian geranium oils.—Perf. & Ess. Oil Ree.
1916, v. 7, p. 91.
Baker, R. T., and Smith, H. G.: Analytical notes on the oil of
the leaves of Darwinia glandifiora—=J. Proc. Roy. Soc. New South
Wales, Sydney, 1916, v. 50, p. 181-186.
Schorger, A. W.: Experimental data relating to the physical and
chemical constants of the leaf and twig, and bark oils of incense
cedar.—J. Ind. & Eng. Chem. 1916, v. 8, p. 22-24.
Anon.: A brief note on the habitat and uses of Indian lemon-grass
oil.—Perf. & Ess. Oil Rec. 1916, v. 7, p. 333.
Umney, J. C.: Data showing the decrease in citral content of
Bourbon and Cochin Jemon-grass oils on storing.—Perf. & Ess. Oil
Ree. 1916, v. 7, p2 94:
Jacobson, C. A.: Notes on essential oils from some Nevada desert
plants.—Rep. Nevada Agric. Exper. Sta. 1916, p. 44-45.
Yoshida, Naozo: Kimura has shown that the volatile oil obtained.
from the wood of Cryptomeria japonica consists of two sesqui-
terpenes, cadinene and suginene, and a sesquiterpene alcohol, erypto-
meriol. The latter has distinct antiseptic properties——J. Pharm.
Soc. Japan, 1916, July, p. 571. .
Tsakalotos and Papaconstantinu: Pinene hydrochloride, pinene —
hydrebromide and camphene prepared from pinene obtained from
the Grecian oil of turpentine showed an optical rotation of +-33.19°,
+51.31°, and +84.05°, respectively.—J. pharm. et chim. 1916, v. 14, ©
Dafoe
Trier, G.: Some remarks on azulene, the blue hydrocarbon con-
tained in certain volatile oils—Schweiz. Apoth.-Ztg. 1916, v. 54, p.
70-71.
Semmiler and Liao: A description of the properties of elemol, a
new sesquiterpene obtained from Manila elemi.—Chem. & Drug. 1916, —
v. 88, p. 876.
Puxeddu, E., and Scaffidi, L.: A study of the polymers of anethole
and isosafrole-—Gaz. Chim. Ital. 1916, v. 46, p. 169-176.
Francisconi and Servagiotto: The characteristics and properties‘of —
a nitrosochloride prepared from the oil of Bupleurum fruticosum are
described.—Chem. & Drug. 1916, v. 88, p. 737.
241
Brooks, Benjamin T.: The author has isolated a sesquiterpene al-
eohol, C,,H.,0, from the volatile oil of ginger. He has given the
cohol the name of “ zingiberol.”—J. Am. Chem. Soe. 1916, v. 38,
p. 480-432.
_ Hood, C. S.: The oil obtained from Wonarda punctata gathered in
Florida yielded 52 to 62 per cent of phenols, most of which was
thymol.—Bull. U. S. Dept. Agric. 1916, No, 872, p. 1-12.
_ Hargreaves, G. W.: A report of an investigation of the oil of the
bark and leaves of Cinnamomum Oliveri, commonly known as Bris-
bane sassafras. An abstract.—Chem. & Drug. 1916, vy. 88, p. 973.
Roberts, O. D.: A report of a chemical examination of the oil of
Cedrus odorata—J. Chem. Soc. Lond. 1916, v. 109, p. 791-796.
Kafuku, K.: A presentation of experimental data relative to the
composition and properties of a volatile oil obtained from Liguid-
ambar Formosana.—Chem. Abstr. 1916, v. 10, p. 2386.
Asahina and Kashiwaki: In an examination of the essential oil
‘distilled from the fruits of Hvodia rutaecarpia, the authors isolated
‘an aliphatic terpene which they have named “evodene.” An ab-
stract—Chem. & Drug. 1916, v. 88, p. 53. :
Russell, G. A.: A report of the distillation and chemical examina-
tion of a volatile oil obtained from Muthamia Caroliniana, a plant
‘growing on the moist sandy soil of the eastern coast of the United
States, especially in Florida—J. Am. Chem. Soc. 1916, v. 38, p.
1898-1400.
Pearson, R. S.: The two varieties of Cymbopogon known by the
Hindus as “ motia” and “sofia” are to be cultivated at Dehra Dun,
India, for the purpose of determining their botanical relationship.—
ePharm. J. 1916, v. 97, v. 251.
Kafuku, K.: Notes on the composition and properties of the For-
“ mosa variety of citronella oil.—Chem. Abstr. 1916, v. 10, p. 1908.
_ Sealione, C. C.: Experimental data relating to the composition
and properties of a volatile oil obtained from Calycanthus occiden-
talis, a plant growing in northern California and southern Oregon,
are presented.—J. Ind. & Eng. Chem. 1916, v. 8, p. 729-730.
OLEUM AMYGDALZ AMARZE.
Anon.: Notes on the production and evaluation of oil of bitter
almond.—Perf. & Ess. Oil Ree. 1916, v. 7 p. 276-278.
Anon.: In the U. S. P. benzaldehyde assay, the end point with
methyl orange is not sharp, and the method can not be considered a
‘satisfactory one. The low minimum of benzaldehyde required (85
per cent) is practically an admission that low results are obtained
"by this procedure. The most satisfactory method for the deter-
110095°—19—16
242
mination of benzaldehyde is by absorption with a saturated solution:
of sodium bisulphite, when no uncombined portion should remain.—
Perf. & Ess, Oil Rec. 1916, v. 7, p. 344.
OLEUM ANISI.
Editorial: A review of the developments in the purification and
commerce of anise oil.—Perf. & Ess. Oil Rec. 1916, v. 7, p. 59-60.
Anderson, George E.: Importations of oil of anise from Hone-
keng increased during the year 1915 as a result of the low price
caused by the decreased demand for the oi] in Europe.-—Com. Rep. —
1916, No. 88, p. 180.
Anon.: In the new edition of the Finnish pharmaccpeeia, the mono-
graph for anise oil reads as follows: Specific gravity at 20° C.,
0.980 to 0.990; it congeals at 17° C. and is soluble in three times its —
volume of 90 per cent aleohol—Am. Perf. 1916, v. 11, p. 94.
Anon.: The congealing point test for anise oil as given in the U. —
S. P. IX is not a good one, as the congealation is very frequently —
unsatisfactory unless it starts at more than 3° below the finally —
determined temperature.—Perf. & Ess. Oil Rec. 1916, v. 7, p. 300.
Clampett, G. W.: Of seven samples of oi] of anise examined, the
anethol content ranged from 60 to 85 per cent.—Proc. Texas Pharm.
Assoc. 1916, p. 80.
Vanderkleed, C. E.: Two lots of anise oil examined were found to —
be optically inactive, but answered all other U. S. P. requirements.—
J. Am. Pharm. Assoc. 1916, v. 5, p. 541.
OLEUM AURANTII.
Hood, Samuel C.: A report of investigations relative to the possi- —
bility of the commercial production of orange oil from waste
oranges.—Bull. U. S. Dept. Agric. 1916. No. 399, p. 1-19, ;
Anon.: Notes on the various commercial varieties of oil of —
orange.—N. A. R. D. J. 1916, v. 22, p. 889.
Hood, S. C.: Data showing the relative oil yield of Florida
oranges.—J. Ind. & Eng. Chem. 1916, v. 8, p. 709-711.
OLEUM BERGAMOTTA, N. F.
Lea, E. J.: A sample of oil of bergamot examined was highly
adulterated with other oi]—Bull. California Bd. Health, 1916, y. 12,
p. 112.
OLEUM BETULZ EMPYREUMATICUM RECTIFICATUM, N. F.
Anon.: Notes on the preparation, composition, and properties of
birch-tar oil.—Perf. & Ess. Oil Rec. 1916, v. 7, p. 808-309.
243
OLEUM CADINUM.
Nuerre: By distillation with steam, Juniperus oxycedrus yields
1.6 to 3.1 per cent of a volatile oil. This oil is stated to be free from
the disagreeable odor of the oil obtained by destructive distillation
_and to be equally as effective as the latter in dermatosis. The
physical constants of the oil are given. An abstract—Drug. Circ.
» 1916, v. 60, p. 20.
; OLEUM CAJUPUTI.
Anon.: The fact that the U. S. P. LX does not include an assay for
_ eucalyptol in this oil is stated to be a mistake.—Perf. & Ess. Oil Rec,
1916, v. 7, p. 300.
- . OLEUM CARYOPHYLLI.
_ Anon.: In the new edition of the Finnish pharmacopoeia, the
~ monograph for oil of cloves reads as follows: Specific gravity at 15°
C., 1.044 to 1.070; it is soluble in twice its volume of 70 per cent
' alechol—Am. Perf. 1916, v. 11, p. 94.
Clampett, G. W.: In five samples of oil of cloves examined, the
_ eugonol content ranged from 60 to 83 per cent—Proc. Texas Pharm.
| Assoc. 1916, p. 80.
K’we, G. E.: One lot of oil of cloves examined was brown in
color.—Proc. Pennsylvania Pharm. Assoc. 1916, p. 115.
OLEUM CASSLE.
Anderson, George E.: Shipments of cassia oil from Hongkong to
the United States dropped off during 1915 owing to a rise in price
~ and to the fact that American manufacturers object to the presence
— of so much rosin in the Chinese product.—Com. Rep. 1916, No. 88,
& p. 180.
Anon: In the new edition of the Finnish pharmacopeeia, the mono-
graph for cil of cinnamon reads as follows: Specific gravity 15°
C., 1.023 to 1.040; it is soluble in three times its volume of 70 per
_eent alcohol— Am. Perf. 1916, v. 11, p. 94.
_ <Anon.: The specific gravity limit, 1.045 to 1.063, is wider than
' necessary for 80 per cent oils—Perf. & Ess. Oil Rec. 1916, v. 7,
_ p. 300.
~ <Anon.: A note on a method for the removal of lead from cassia
_ oil.—Ztschr. angew. Chem. 1916, v. 29, p 518.
Sally, J. K.: Oil of cassia is sometimes substituted for oil of Ceylon
cinnamon.—Oil, Paint & Drug Rep. 1916, v. 90, No. 16, p. 46.
' Clampett, G. W.: Of five samples of oil of cinnamon examined,
_ the cinnamic aldehyde content ranged from 60 to 82 per cent. In
four other samples the aldehyde content was between 73 and 90 per
- cent.—Proc. Texas Pharm. Assoc. 1916, p. 80.
244
GLEUM CHENOPODII. ae
Anon.: The U. S. P. limits for the oil of wormseed might have
been a little more restricted. A specific gravity of 0.955 is too low
for most good oils, and many are soluble in three volumes of 70 per
cent alcohol, while some are not soluble in eight volumes.—Perf. &
Ess. Oil Rec. 1916, v. 7, p. 300.
Anon.: Paolini and Lomonaco report that Italian wormseed oil —
contains alpha and beta thujone, thujyl alcohol, phellandrene, and
eadinene. The thujyl alcohol is present in the free state, and also
in the form of acetic, isovalerianic, and palmitic esters—Perf. & Ess.
Gai Ree. 1916,-v.-7, p- 00:
Stheman: A report on the adulteration of oil of chenopodium.
with oil of eucalyptus and oil of anise-—Drug Cire. 1916, v. 60,
p. 273.
Vanderkleed, C. E. One lot of oil of wormseed examined was
found to be adulterated with 44 per cent of a fixed oi]. Oil of worm-
seed ordinarily averages 1.5 per cent of nonvolatile residue.—J. Am.
Pharm. Assoc. 1916, v. 5, p. 542.
Salant, William, and Livingston, A. E.: A report of experiments
with oil of chenopodium and cardiac stimulants on the isolated frog
heart—Am. J. Physiol. 1916, v. 41, p. 21-38.
Salant, Wilham, and Bengis, Robert: A study of the renal
changes produced by oil of chenopodium and fatty oils, and of the
protective action of diet on the kidney.—J. Pharmacol. & Exper.
Therap. 1916, v. 9, p. 529-554.
Coutant, A. F.: A report on the history of a case of poisoning by
chenopodium oil employed in the treatment of hookworm. The
atithor also cites 12 other cases of poisoning reported in the litera-
ture.—J. Am. M. Assoc. 1916, v. 67, p. 1593-1596.
OLEUM CUBEB.
Anon.: There does not seem to be any adequate reason for omitting
the refractive index in prescribing constants for the oil of cubeh,
and fractional distillation figures ought to be included.—Perf. &
Ess. Oil Rec. 1916, v. 7, p. 300.
roberts, J. G.: Two oils distilled from mixtures of cubeb stems
and berries had optical rotations of —16° 47’ and —17° 13’.—Proe.
Pennsylvania Pharm. Assoc. 1916, p. 115.
OLEUM EUCALYPTI.
Anon.: Notes on the cultivation of eucalyptus in India.—Perf.
& Ess. Oil Rec. 1916, v. 7, p. 891-392.
Smith, Henry G.: Notes on some of the physical and chemical
constants of the essential oil from the bark of Kucalyptus macar-
245
thuri.—J. Proc. Roy. Soc. New South Wales, Sydney, 1916, v. 50,
>. 177-180; see also Perf, & Ess. Oil Rec. 1916, v. 7, p. 46. ~
~ Lilly, J. K.: An oil of a different type from that of Eucalyptus
globulus has been substituted for the U. S. P. product—Oil, Paint
& Drug Rep. 1916, v. 90, No. 16, p. 46.
Anon.: If 70 per cent oils are the minimum, it is quite unnecessary
to have so low a specific gravity as 0.905 at 25° C., as the two values
are practically incompatible—Perf. & Ess. Oil Rec. 1916, v. 7, p. 300.
_ E’we, G. E.: Only two of eight lots of oil of eucalyptus examined
met the U. S. P. IX requirement of 70 per cent cineol. All of the
others met the U. S. P. VIIT requirement of 50 per cent.—Proc.
Pennsylvania Pharm. Assoc. 1916, p. 115.
Roberts, J. G.: The cineol content of one lot of oil of eucalyptus
examined was 6 per cent below the U. S. P. standard of not less than
50 per cent. Two other shipments were satisfactory in every respect.—
Proc. Pennsylvania Pharm. Assoc. 1916, p. 116.
Editorial: Comments on the Milne method of treating scarlet
fever and measles. The spreading of the infection is prevented by
rubbing the entire body with eucalyptus oi]—Perf. & Ess. Oil Ree.
1916, v. 7, p. 3.
OLEUM GAULTHERI.
Anon.: A short note giving information relative to the cultiva-
tion of wintergreen in America.—_N. A. R. D. J. 1916, v. 21, p. 805.
OLEUM LAVENDUL&.
- Vivaudou, V.: An account of the cultivation of lavender in Eng-
Jand and France and of the preparation of the oil therefrom—
Pharm. Era, 1916, v. 49, p. 223-226.
Anon.: Short descriptions of the four commercial kinds of oil of
Javender on the market.—N. A. R. D. J. 1916, v. 21, p. 918.
~ Anon.: Schimmel & Co. report that from their experiments they
are unable to confirm the statement of Elze to the effect that thymol
is a normal constituent of oil of lavender—Perf. & Ess. Oil Ree.
1916, v. 7, p. 50.
Umney, J. C.: From an examination of 250 samples of spike laven-
der oil, the author concludes that genuine oils yield from 30 to 35
per cent of alcohols and that an oil containing less than 30 per
cent is adulterated.—Perf. & Ess. Oil Ree. 1916, v. 7, p. 289-241.
Anon.: A note calls attention to the use. of lavender oil in the
treatment of infected wounds.—Perf. & Ess. Oil Ree. 1916, v. 7, p. 105.
OLEUM LIMONIS.
Anon.: Brief notes on the production and properties of lemon
oil_— Perf. & Ess. Oil Rec. 1916, v. 7, p. 283-254.
246
Anon.: In the new edition of the Finnish pharmacopoeia, the
monograph for oil of lemon reads as follows: Specific gravity, 0.855
to 0.861; it is soluble in 12 times its volume of 90 per cent alcohol.—
Aim. Perf. 1916, v. 11, p. 94.
Anon.: The unjustifiable figures 0.851-0.855 at 25° C. are now
official for specific gravity, while the optical rotation has been altered
to +57° to +64°, which is at least more reasonable. These figures,
however, as those of the British pharmacopeeia, can not possibly be
justified by experience, and in some seasons the fruits of this pa-
rochial narrowmindedness will be found in wholesale rejections of
the very finest samples of pure lemon oil.—Perf. & Ess. Oil Ree.
1916, v. 7, p. 300.
Anon.: In commenting on the natural variation of lemon oil, it is
stated that the optical rotation limits of +58° to +64° exelude the
richest oils, and in 1914-1915 would have barred the crop from the
Messina district.—Perf. & Ess. Oil Rec. 1916, v. 7, p. 382.
Bennett, A. H.: Descriptions of some of the characteristics of, and
tests for lemon oil.—Chem. Abstr. 1916, v. 10, p. 1400 from Boll.
dela Camera Agrumaria, 1915, vy. 1, part 5, p. 23-24.
Lauffs: A sample of lemon oil examined was found to be adulter-
ated with 50 per cent of paratin and considerable quantities of oil
of turpentine. An abstract—C. U. C. P. Alumni J. 1916, v. 23, p. 87.
Swift, E. G.: Both the natural and concentrated oil of lemon are
frequently low in citral content.—Oil, Paint & Drug Rep. 1916. vy. 90.
No. 16, p. 46.
Clampett, G. W.: Of three samples of oil of lemon examined, the
citral content ranged from 1.5 to 3.07 per cent—Proc. Texas Pharm.
Assoc. 1916, p. 80.
K’we, G. E.: All oil of lemon assayed by the Umney method was
satisfactory in citral content. One lot labeled “ Oil of lemon, extra
strong,” assayed 12.55 per cent citral by the Umney method.—Proc.
Pennsylvania Pharm. Assoc. 1916, p. 116.
Vanderkleed, C. E.: Six lots of lemon oil assayed by the method
of J. C. Umney showed a citral content ranging between 3.52 and
4.32 per cent.—J. Am. Pharm. Assoc. 1916, v. 5, p. 541.
OLEUM MENTH PIPERITA.
Rabak, Frank: The effect of cultural and climatic conditions on
the yield and quality of peppermint cil.—Bull. U. S. Dept. Agric.
1916, No. 454, p. 1-16.
Anon.: In the new edition of the Finnish pharmacopeia, the
specific gravity for oil of peppermint at 15° C. is given as 0.900 to
0.910.—Am. Perf. 1916, v. 11, p. 94.
Anon.: No “unofficial” analyst would use the detailed processes
given for menthol determination. The acetylated oil is usually not
eS eee
247
washed with sodium carbonate solution until alkaline to phenolphtha-
lein nor is 50 cubic centimeters of - potassium hydroxide V. S. used
for the saponification.—Perf. & Ess. Oil Rec. 1916, v. 7, p. 301.
OLEUM MENTHZE VIRIDIS.
Holmes, E. M.: The plant yielding this oil is referred to as Menthu
spicata Linné (Mentha viridis Linné). In this case the application
of the law of priority fails, since it is evident that Linneus himself
recognized that JMentha viridis, which is the source of the garden
mint known as spearmint, is a distinct species, and he subsequently
separated it from Jentha spicata—Pharm. J. 1916, v. 97, p. 485.
OLEUM MYRCIZ, N. F.
Anon.: Notes on commercial samples of oil of nutmeg and mace.-—
N. A. R. D. J. 1916, v’ 21, p. 918.
Zibriskie, Luther K.: A consular report on the bay oil industry of
the Danish West Indies.—Com. Rep. 1916, No. 161, p. 115.
Anon.: A table showing the relation of specific gravity to the
phenol content of oil of bay.—Perf. & Ess. Oil Rec. 1916, v. 7, p. 295.
OLEUM MYRISTICZ.
Anon.: Notes on commercial samples of oil of nutmeg and
mace.—N. A. R. D. J. 1916, v. 21, p. 918.
OLEUM PIMENT€.
Clampett, G. W.: The ecugonol content of one sample of oil of
pimenta examined was 80 per cent.—Proc. Texas Pharm. Assoc.
1916, p. 80.
OLEUM PINI PUMILIONIS.
Holmes, E. M.: The name of the plant yielding this oil is given
as Pinus montana Miller. As there are three other species of Pinus
to which the name of P. montana has been applied, and as the
name Pumilio has been retained for the oil, it appears to be stretch-
ing a point to apply the law of priority so strictly —Pharm. J. 1916,
vy. 97, p. 485.
Record, Samuel J.: An account of the pine needle oil industry of
Sweden.—Scientific American, 1916, v. 114, p. 100-101,
OLEUM ROS.
Martell, P.: An account of the cultivation, collection and dis-
tillation of Damascus and white roses in Bulgaria.—Schweiz. Apoth.-
%ite. 1916, v. 54, p. 405-408, 420-425.
248
Anon.: In the new edition of the Finnish pharmacopeeia, the mono--
eraph for oil of rose reads as follows: Specific gravity at 30° C.._
9.850 to 0.863; it solidifies at 18° C.—Am. Perf. 1916, v. 11, p. 94. .~
Anon.: Tables showing the physical and chemical constants of the
otto ef rese from various sources.—Perf. & Ess. Oil Rec. 1916, v. 7,
pets. i
Lilly, J. K.: Some of the oil of rose examined was found to be
adulterated with oil of geranium.—Oil, Paint & Drug Rep. 191.
v. 90, No. 16, p. 46.
OLEUM ROSMARINI.
Anon.: Notes on the cultivation of rosemary in Tunis.—Perf. & —
Ess. Oil Rec. 1916, v. 7, p. 214-215.
' OLEUM SABINZE.
Anon.: A note on the physical and chemical constants of Spanish —
savin oil, prebably derived from Juniperus phoenicea—Perf. & Ess.
Oil Rec. 1916, v..7, p: 6T.
Pally, J. K.: Several lots of oi] of savin were found to be adul-
terated with oil of turpentine.—Oil, Paint & Drug Rep. 1916, v. 90,
No. 16, p. 46. .
OLEUM SANTALI.
Anon.: A consular report on the distillation of sandalwood oi] in
India.—Com. Rep. 1916, No. 103, p. 422.
Briggs, C. H.: Notes on the yield of 011 obtained from sandalwood
and on the changes taking place in the oi] during distillation.—J.
Ind. & Eng. Chem. 1916, v. 8, p. 428-429; see also Chem. Abstr. 1916,
¥ 10s pi dog
Anon.: Notes on sandalwood and its oil, including a description of
the properties and the constituents of the latter—Perf. & Ess. Oil
Ree. 1916, v. 7, p. 68-70:
Anon.: In the new edition of the Finnish pharmacopoeia, the
monograph for oil of santal reads as follows: Specifie gravity at —
15° C., 0.973 to 0.985; it dissolves in six times its volume of 70 per
cent aleohol—Am. Perf. 1916, v. 11, p. 94.
Anon.: It is a pity that an ester limit is not given for oil of san-
dalwood, as adulteration with castor oil in small quantity is easily —
detected by an ester determination.—Perf. & Ess. Oil Rec. 1916, v.
op p. 301.
Clampett. G. W.: Of seven samples of oil of sandalwood exam-
ined, the santalol content ranged from 60 to 90 per cent.—Proc. Texas
Pharm. Assoc. 1916, p. 80.
Lea, E. J.: A sample of sandalwood oi] examined was almost en-.
tively a substitute product.—Bull. California Bd. Health, 1916, y. —
12, ps 112, :
249
OLEUM SASSAFRAS.
Holmes, E. M.: The well-known name Sassafras officinale las
been changed to Sasafras variifolium (Salisbury) Otto Kuntze, in
deference to the law of priority, but the plant was described by Sal-
isbury as a Laurus and nothing is therefore gained by the change.—
Pharm. J. 1916, v. 97, p. 485.
OLEUM SINAPIS VOLATILE.
Tsakalotos, D, E.: A presentation of data showing the yield, com-
position, and physical constants of the volatile oil obtained from the
black mustard seed grown in Greece.—J. pharm. et chim, 1916, vy. 138,
p. 78-80. ;
Anon.: In the new edition of the Finnish pharmacopeeia, the spe-
_cifie gravity for oi] of mustard is given as 1.022 to 1. 025 at 15° C.—
Am. Perf. 1916, v. 11, p. 94.
OLEUM TEREBINTHINS.
Anon.: A discussion of the prospects for an indigenous oil of
turpentine industry in Germany.—Siidd. Apoth.—-Ztg. 1916, v. 56,
p- 30.
Anon.: Notes on the physical properties of turpentine oil dis-
tilled in India from Pinus longifolia—Chem. & Drug. 1916, v. 88,
p- (82.
Palazzo, F. C.: A report of chemical investigations bearing on the
oil of turpentine from Pinus pinea L.—Ann. chim. applicata, 1916,
vy. 6, p. 185-153.
Posse: A report of a chemical examination of an oil obtained
by heating the woody roots of Norwegian pine and fir with sulphite
liquor at a pressure of 6 to 8 atmospheres. An abstract—Pract.
Drug. 1916, v. 34, No. 8, p. 39.
~ Anon.: A discussion of the qualities and properties of oil of tur-
pentine, wood and gum oils—Perf. & Ess, Oil Rec. 1916, v. 7, p.
109-111.
Béttler, M.: A formula for a mixture of oils and resins proposed
as a substitute for oil of turpentine as a result of the shortage of the
latter in Germany.—Chem. & Drug. 1916, v. 88, Supp. 34.
Krieger, A.: A description of a modification of Armstrong’s
methed for the detection of aromatic hydrocarbons and petroleum
| spirit in turpentine-—Chem. Ztg. 1916, v. 40, p. 472-473; see also J.
Soc. Chem. Ind. 1916, v. 35, p. 746.
Coen: A description of a method for the detection of camphor
oil in oil of turpentine. An abstract—Ann. Falsif. 1916, v. 9,
p. 318.
250
Hollande, A. Ch.: Methods for the identification of petroleum oil
and oil of turpentine in the pus of abscesses caused by the subcuta-
neous injection of these substances.—J. pharm. et chim, 1916, v. 13,
p. 337-340; also see Chem. Abstr. 1916, v. 10, p. 2357. J
Prins, H. J.: A study of the isomerization, polymerization, and
addition reactions of a#-pinine-—Chem. Weekblad, 1916, v. 13, p.
1294-1296.
Rimini, Enrico: A note on the transformation of nopinine.—Gaz. —
Chim. Ital. 1916, v. 46, p. 119-121.
Anon.: Of 45 samples of oil of turpentine examined, 6 were
rejected for being of poor quality.—Rep. Connecticut D. & F. Com.
1916, p. 19.
Barnard, H. E.: One sample of oil of turpentine examined was
rejected for being adulterated.—Bull. Indiana Bd. Health, 1916,
v. 19, p. 112.
Congdon, Leon A.: One sample of spirit of turpentine examined
was not of U.S. P. quality—Rep. Kansas Bd. Health, 1916, p. 133.
OLEUM THYMI.
Clampett, G. W.: Of seven samples of oil of thyme examined, the
thymol content ranged from 16 to 30 per cent.—Proc. Texas Pharm.
Assoc. 1916, p. 80.
OLEATUM HYDRARGYRI.
Murray, B. L.: A description of an electrolytic method for the
determination of mercury in oleate of mercury.—J. Ind. & Eng.
Chem. 1916, v. 8, p. 257.
OLEORESINA ASPIDII.
Anon.: The specific gravity, refractive index, solubility in various
solvents, content of filicic acid, and various other features are now
well defined, and a determination of these values is a certain safe-
guard against adulteration. But the compilers of the U. S. P. IX
have not included one single test for this important substance.—
Perf. & Ess. Oil Rec. 1916, v. 7, p. 302; see also Chem. & Drug. 1916,
y. 88, No. 1921, p. 45.
OPII PULVIS.
E’we, G. I.: Of three samples of powdered opium assayed, the
crystalline morphine content of one was above standard and two
below.—Proc. Pennsylvania Pharm, Assoc. 1916, p. 119.
Vanderkleed, C. E.: Six lots of powdered opium examined as-
sayed from 11.84 to 12.58 per cent of morphine.—J. Am, Pharm.
Assoc. 1916, v. 5, p. 542.
Te er ee ee ee ae ete ye
251
OPIUM.
‘ Svirlevski: Notes on the cultivation of the poppy in Persia and on
the preparation of opium therefrom. The morphine content gen-
erally varies from 4.4 to 11.1 per cent. An abstract.—J. pharm. et
chim. 1916, v. 13, p. 387.
Kehl, John E.: Drug and chemical situation in Greek Macedonia.
The quantity of opium shipped from Saloniki during the year
amounted to 173 metric tons. Of this amount, 161,849 pounds found
its way to the United States—Com. Rep. 1916, No. 5, p. 93.
Anon.: The importations of opium into the United States dropped
from 400,000 pounds in 1914 to 300,000 pounds in 1915.—Com. Rep.
1916, No. 14, p. 243.
Wilbert, M. I.: A review of the recognition accorded to opium, its
preparations, alkaloids, and derivatives in the several editions of the
United States Pharmacopeeia.—J. Am. Pharm. Assoc. 1916, v. 5,
p. 688-693.
Holmes, E. M.: In specifying the source of opium, it is not under-
_ stood why the variety album De Condolle is mentioned, as it would
be impossible to state whether any specimen of opium had been col-
lected from the purplish-red or white-flowered variety —Pharm. J.
1916, v. 97, p. 485.
Beringer, George M.: According to the specifications of the new
edition of the U. S. P., opium must now contain not less than 9.5
_ per cent of anhydrous morphine instead of not less than 9 per cent
of crystallized morphine as in the older edition—Am. Druggist,
1916, v. 64, No. 8, p. 24.
Smith, Carl E.: A comparison of the U. S. P. and Ph. Brit.
methods for the assay of opium. The author concludes that the fore-
going methods give fairly accurate results with a tendency toward
high results. For rapid approximate results he favors lime methods
of the type adopted by the Ph. Germ. V.—Am. J. Pharm. 1916,
vy. 88, p. 292-301.
Guerin, C.: A new modification of the lime method for the assay
of opium is described. An abstract.—C. U. C. P. Alumni J. 1916,
v. 23, p. 168.
Shilston, H. P.: Data obtained in routine morphinometrie assays
of opium by a slightly modified Ph. Brit. method.—Chem. News,
1916, v. 114, p. 273-275.
Vanderkleed, C. E., and E’we, G. E.: The impression is quite preva-
lent that if, in conducting an opium assay, the morphine is allowed
to stand for crystallization for a longer time than 16 hours, the
morphine will be less pure and more difficult to filter off and wash.
Experiments conducted by the authors show that this impression is
erroneous.—J. Am. Pharm. Assoc. 1916, v. 5, p. 717-718.
202
Summers, F. P., et al.: A discussion of assay methods for surgi-
cal dressings and opium preparations.—Chem. Abstr. 1916, v. 105
p- 1402.
Anon.: Of 102 samples of Indian opium examined at the Tmpatiail
Tnstitute, 51 showed an average morphine content of 10.26 per cent,
21 contained only 7.5 per cent, and 30 contained so little morphine
that they were of no medicinal value-——Pharm. Weekblad, 1916, v. 53,
p- 19%.
Anon.: The crystalline morphine content of four samples of opium
was above standard, One sample assayed 20.32 per cent.—Proc.
Pennsylvania Pharm. Assoc. 1916, p. 119.
Vanderkleed, C. E.: The morphine content of nine samples of
opium examined ranged between 11.31 and 12.35 ver cent.—J. Am.
Pharm. Assoc. 1916, v. 5, p. 542.
Greenish, Henry G.: Ath illustrated account of the preparation eS:
smoking opium.—Pharm. J. 1916, v. 96, p. 517-518.
Simons, Frank D.: Investigations relative to the comparison and
identification of various types of smoking opium.—J. Ind. & Eng.
Chem. 1916, v. 8, p. 345-3851.
Thum, John K.: A review of the annual report of the chemical
laboratory of the American Medical Association, volume 8, directs
attention to the data given therein on the examination of comin
specimens of opium alixaloids—Am. J. Pharm. 1916, v. 88, p. 574.
Perkin, Wm. H., jr.: A report of researches dealing with the com-
position and properties of eryptopine and protopine, two rare opium
alkaloids.—J. Chem. Soc. Lond. 1916, v. 109, part 2, p. 815-1028.
Stephan, A.: A description of a method for preparing a 10 per
cent sterile solutien of the glycerophosphates of the total alkaloids of
opium. The preparation contains 50 per cent of morphine and 20
per cent of secondary alkaloids and is sold under the name of “ gly-
kopon.”—Chem. Zentralbl. 1916, v. 87, part 2, p. 514 from Apoth. ak
1916, v. 81, p. 351.
Mayer, F.: Holopon is obtained from opium by means of ultra-
filtration. It is an aqueous solution containing all the active con-
stituents of opium in their natural quantitative relationship freed
from disturbing ballast as fats, resins, wax, and proteins. Three parts
of the clear light brown fluid correspond to one part opium. It canbe
administered subcutaneously, intramuscularly, and intravenously.—
Deutsch. med. Wehnschr. 1916, v. 42, p. 224-295 through Chem.
Abstr. 1916, v. 10, p. 1690.
Schlomer, George: A report on the use of holopon, a new opium
preparation, in neurology and psychiatry.—Deutsch. med. Wehnschr.
1916, v. 42, p. 1008,
253:
~ Macht. David I., Herman, N. B., and Levy, Chas. S.: A quanti-
ative study of the analgesia produced by opium alkaloids, individ-
ially and in combination with each other, in normal man.—Rep.
Therap. Res. Com. 1916, v. 5, p. 27-61; J. Pharmacol. & Exper.
Therap. 1916, v. 8, p. 1-87.
Macht, David I.: A study of the peripheral action of the alka-
Joids, with special reference to the effect on the sensory nerve ter-
minals.—J. Pharmacol. & Exper. Therap. 1916, v. 8, p. 451-463.
Jackson, Dennis E.: A report ef researches relative to the periph-
eral action of opium alkaloids, with special reference to the blad-
der.—J. Lab. & Clin. Med. 1916, v. 1, p. 862-879.
Macht, David I.: Researches to determine the action of opium al-
kaloids on the ducts of the testis —J. Pharm. 1916, v. 9, p. 121-127.
Macht, David I.: A comparative study of the effects of opium
derivatives, individually and in combination with each cther, on
the gall bladder—ZJ. Pharmacol. & Exper. Therap. 1916, v. 9, p.
473-481.
Editorial: A discussion of the effect of certain opium alkaloids
upon respiration.—J. Am. M. Assoc. 1916, v. 66, p. 514-515.
Macht, David I.: A report of an investigation of the pharma-
cological action of papaverine —Arch. Int. Med. 1916, v. 17, p. 786—-
806.
Wood, Horatio C.: A discussion of the value of opium as a local
remedy.—J. Am. M. Assoc. 1916, v. 66, p. 1072-1073.
OVI VITELLUM RECENS, N. F.
Spohn, Adelaide, and Riddle, Oscar: Data showing the composi-
tion of white and yellow egg yolk of the common fowl and the
pigeon are given.—Am. J. Physiol. 1916, v. 41, p. 597-408.
Anon.: The principal pigment of egg yolk is stated to belong to
‘the xanthophyll group of plant pigments. The color of the yolk
may therefore be controlled by feeding the proper amounts of
xanthophyll containing foods.——Pharm. J. 1916, v. 96, p. 440.
Anon.: A description of tests for the evaluation of egg yolk.—
Perf. & Ess. Oil Rec. 1916, v. 7, p. 99.
Bandrexel, A.: A description of a biological method for the posi-
tive determination of the presence of a preservative in egg yolk.—
Chem. Abstr. 1916, v. 10, p. 2942.
OVUM GALLINACEUM, N. F.
Pennington, M. E.: A study of packing-house conditions with
laboratory data furnish information relative to the proper handling
of eggs in egg-breaking houses to insure a clean product.—Bull. U. 5.
Dept. Agric. 1916, No. 224, p. 1-99.
254
Gruber, H. T.: A pepsin test for determining the freshness of eggs
is described in detail. The test is based on the fact that the digesti- |
bility of the albumen decreases with age.—J. Ind. & Eng. Chem.
1916, v. 8, p. 911.
Rettger, Leo F.: A report of feeding experiments with Bacterium
pullorum to determine the toxicity of eggs infected with this or-
ganism.—J. Exper. M. 1916, v. 23, p. 475-489.
OXYGENIUM.
Smithhurst, P. A.: A compact apparatus for automatically gener-
ating and storing oxygen under pressure. British Patent No. 1,400, —
Jan. 28.—Chem. Abstr. 1916, v. 10, p. 1918.
Hazard-Flamand, M.: U. S. Patent No. 1,201,043-4. An appara-
tus and method for fractionally liquifying oxygen from the air.—
Chem. Abstr. 1916, v. 10, p. 3142.
MacArthur, C. G.: Data showing the solubility of oxygen in salt
solutions and the hydrates of these salts are presented.—J. Phys.
Chem. 1916, v. 20, p. 495-502.
Anon.: A. discussion of the uses of ozone in chemical research and
in the industries—Chem. News, 1916, v. 113, p. 193-196 and 205-206.
Anon.: In connection with a description of a breathing appara-
tus, the effects of breathing pure undiluted oxygen are discussed.
Contrary to general opinicn, no marked effects are noticeable.—Sci-
entific American, 1916, May 13, p. 50T.
Wood, W. A.: A method for the continuous oxygenation of wounds
with oxygen under a pressure of 3 to 4 pounds is described.—Brit.
M. J. 1913, v. 2, p. 508.
Dumarest: The repeated injection of oxygen is recommended in
the treatment of “frost foot.” The treatment is reported to have
given excellent results in a number of cases. An abstract—Pharm.
J. 1916, v. 96, p. 133.
PANCREATINUM.
Long, J. U., et al.: A report of investigations to determine the
digestive activity and composition of different fractions of the pan-
ereas. The different fractions were obtained by centrifuging the
minced tissues.—Rep. Therap. Res. Com. 1916, v. 5, p. 22-26.
Long, J. H., et al.: A report of researches to determine whether
or not trypsin is destroyed by pepsin and acid. It was found that
when the acid concentration is reduced to Py=2.6 or less, tryptie ac-
tivity persists for several hours at the body temperature —J. Am.
Chem. Soc. 1916, v. 38, p. 1620-1638.
Long and Fenger: From work on the pancreatic glands of sheep,
hogs, and oxen, these authors confirm their original statements with
reference to the acidity of fresh secretions—J. Am. Chem. Soe.
1916, v. 38, p. 1115,
ee eer ne et f Br nl ele eee oe ed
2
‘a
4
2
295
- Leviton, Max B.: The effect of pancreatin in the treatment of
_ goiter, In two cases of exophthalmic goiter, there was a complete
cessation of exophthalmic symptoms with a recession of the goiter
aiter rectal administration of pancreatin (dosage, about 15 to 29
- grains two or three times a day).—J. Am. M. Assoc. 1916, v. 66,
p. 50.
PAPAVERIS FRUCTUS, N. F.
Anon.: Notes on the cultivation of the poppy plant in Macedonia.
—Oil, Paint & Drug Rep. 1916, v. 90, No. 20, p. 26.
_ Alsberg, C. L.: The attention of the Bureau of Chemistry has
been called to the fact that commercial poppy seed sometimes con-
tains the seed of henbane.—S. R. A.-Chem. 1916, No. 18, p. 43.
True, R. H., and Stockberger, W. W.: A report of physiological
observations on alkaloids, latex, and oxidases in Papaver somniferum.
—Am. J. Bot. 1916, v. 3, p. 1-11.
PARACOTO, N. F.
Todbauer, A., and Kurz, S.: An investigation of the biological
action of cotoin, paracotoin, hydrocotoin, and allied substances ob-
tained from coto and paracoto bark.—Physiol, Absir, 1916, v. 1, p.
329 from Biochem. Ztschr, 1916, v. 74, p. 340-356,
PARAFFINUM.
Mijs, J.: U. S. Patent No. 1,178,532. A method for purifying
parafiin. A preliminary purification is effected by treatment with
sulphurie acid, the oil is then mixed with an equal weight of toluene
at 50-80° C. The insoluble matter is removed and the solution
allowed to cool when the paraftin separates._-Chem. Abstr. 1916. v.
10, p. 1593.
Peezalski, Thadée: A report of an investigation of the effect of
temperature on the structure of paraffin——Compt. rend. acad. se.
1916, v. 162, p. 784-786; see also Chem. Absir. 1916, v. 10, p. 2061.
Anon.: By heating petroleum distillates with lime and caustie
soda, or a mixture of sulphuric and nitric acids, products which ave
soluble in alkaline solutions are obtained. An abstract.—Chem. &
Drug. 1916, v. 88, p. 70.
Anon.: Notes on the use of paraffin and mixtures of petrolatira
and soft paraffin for the injection of fistulous tracts produced by
wounds of war.—J. Am. M. Assoc. 1916, v. 67, p. 897,
PARALDEHYDUM.
Orton, Kennedy J. P., and McIGe, Phyllis V.: A description of
a process for the estimation of paracetaldehyde and acetal in mix-
tures of the two. The method is based on the fact that acetal is
206
rapidly decomposed by heating with traces of strong acids, whereas
paracetaldehyde is not.—J. Chem. Soc. Lond. 1916, v. 109, p. 184-186.
PASTA DERMATOLOGIC. ni be
Unna: Formulas for the preparation of a number of medicated
pastes in which syrup is used in place of glycerin are presented.—
Yearbook of Pharmacy, 1916, p. 438, from Schweiz.—Apoth.-Ztg.
1916, .v. 54, p.: 296.
Ochsner: A formula for Unna’s paste intended for use in the
treatment of varicose veins is given.—J. Am. M. Assoc. 1916, v. 67,
Pb O12.
PELLETIERINA TANNAS.
Loup: A report of a pharmacological study of pelletierine—
Schweiz. Apoth.-Ztg. 1916, v. 54, p. 476-478.
PEPSINUM.
Ringer, W. E.: An investigation of the properties of pure pep-
sin.—Physiol. Abstr. 1916, v. 1, p. 39, from MKolloid-Ztschr. 1916,
v. 19, p. 253-276. .
Aldrich, T. B.: Data showing the relationship of the total nitro-—
gen and z-amino nitregen content of pepsin to its activity —Physiol.
hee 1916, v. 1, p. 40.
Rakuzin, M. A., et al.: A discussion of the limits of sensitiveness
of color reactions for pepsin and other enzymes.—Chem. Abstr. 1916,
v. 10, p. 1655.
Summers, F. P. et al.: Comments on the methods in vogue for the
testing of pepsin. Chem. Abstr. 1916, v. 10, p. 1402.
Graber, Howard T.: From experiments on the testing of pepsin |
with eges of different ages, it is concluded that the strength of the
pepsin can be determined by the age of the egg used in the test and
vice versa.—J. Ind. & Eng. Chem. 1916, v. 8, p. 911.
Vanderkleed, C. E., and E’we, G. E.: E xperiments conducted by
the authers indicate that it is not necessary to read the volume of
undissolved albumen obtained in the pepsin assay at exactly the
end of one-half hour, Reading the volume after standing over night
yields identical results——J. Am. Pharm. Assoe. 1916, v. 5, p. 718.
Okada Seizaburo: Experimental data showing the optimal hydro-
gen ion concentration for the action of pepsin.—Biochem. J. 1916,
v 10, p. 126-129.
Long, J. H., and Hull, Mary: On the assumed destruction of
trypsin by pepsin and acid. Trypsin is not destroyed in the presence —
of protein when the acid concentration is Py=2.6, or below.—Rep.
Therap. Res. Com. 1916, v. 5, p. 124-149; see also J. Am. Chem.
Soe, 1916, v. 38, p. 1620-1638,
207
Ramsay, C. F.: In a study of the retarding effect of certain sub-
ances upon pepsin digestion, the author finds that the added con-
tituents in the preparations of the N. F. do not inhibit the activity
of pepsin, at least in so fie as the test applied is concerned.—J. Am.
*harm. Assoc. 1916, v. 5, p. 30-33.
Hamburger, W. W.., ae Halpern, B.: A study of the effect of salts
on pepsin. Sodium chloride (25 per cent) completely inhibits peptic
activity. This is also a property of many other salts—Arch. Int.
Med. 1916, v. 18, p. 228-234.
Creston J.P. A.: A study of the antiseptic value of gastric juice.
The bacterial action of gastric juice depends entirely on the pres-
ence of hydrochloric acid.—Centralb. f. Bakteriol. 1915, v. 77, p.
353-361.
PERSIO, N. F.
E’we, G. E.: The ash yield of six samples of cudbear examined —
ranged from 7.62 per cent to 60.7 per cent—Proc. Pennsylvania
Pharm. Assoc. 1916, p. 112.
PETROLATUM LIQUIDUM.
Andrews, W. A. P.: A discussion of the origin of the different
paraffin oils and of their physical and chemical properties.—Proc.
Utah Pharm. Assoc. 1916, p. 64-79.
Puckner, W. A.: A description of liquid petrolatum—Squibb, a
heavy California oi]l—J. Am. M. Assoc. 1916, v. 67, p. 953,
Scoville, W. L.: The disappearance of the Russian oil from the
market caused much trouble for a time, but the conditions now are
“met satisfactorily with American oils and the Russian oil is no
longer missed.—J. Am. Pharm. Assoc. 1916, v. 5, p. 542.
Vanderkleed, C. E.: The Russian oil being practically unobtain-
able, recourse must now be had to oil from other sources. These oils
are difficult to obtain free from kerosene taste and fluorescence and
are much lower in specific gravity than is desirable-—J. Am. Pharm.
/Assoc. 1916, v. 5, p. 542.
~ Humphreys, R. E.: A short discussion of the methods of prepara-
tion, properties of, Te tests for petroleum white oils—J. Am.
Pharm. Assoc. 1916, v. 5, p. 304-305.
Brooks, Sain .. The available chemical tests for liquid
-petrolatum are of no value. If the object of the sulphuric-nitric
acid test is nitration, then it should be carried out differently, as
Namjetkin has shown that dilute nitric acid, specific gravity about
1.30, is best for nitrating paraflins and naphthenes.—J. Am. M. Assoe.
(1916, v. 66, p. 24-26.
110095°—19——_17
258
Editorial: According to Benjamin T. Brooks, the American pe-
troleums from the Gulf region, like the Russian, contain no paraffin
hydrocarbons. In the case of the American petroleums that do con-
tain paraftins, the customary refining methods for removing them are
sufficient for producing true naphthene and polynaphthene petrola-
tums. The claim that only Russian oils belong to this class has no
basis in fact and has been advanced presumably for business rea-
sons.—J. Am. M. Assoc. 1916, v. 66, p. 38. :
Briggs, C. H., and Irwin, W. L.: A presentation of experimental
data showing the applicability of the bromine test to the detection
o. minute quantities of unsaturated hydrocarbon in liquid paraflin.—
J. Am. Pharm. Assoc. 1916, v. 5, p. 709-711.
Anon.: Data obtained in the examination of a number of samples
of American liquid parafiin. The specimens examined were low in
specific gravity and did not conform to the requirements of the Ph.
Brit. in other respects.—Lancet, 1916, v. 191, p. 295-294.
Patch, E. L.: The specific gravity of the 12 samples of liquid
paraffin examined ranged between 0.837 and 0.880 ut 25° C. Only
4 of the samples were fluorescent. Several of them gave a dark color
with the sulphuric-acid test.—J. Am. Pharm. Assoc. 1916, v. 5, p. 542.
Roberts, J. G.: Seven lots of medicinal paraffin oil of domestic
origin examined were clear, white products, free from fluorescence,
odor, and taste, neutral to litmus, and had specific gravities ranging
from 0.833 to 0.853 at 25° C.—Proc. Pennsylvania Pharm. Assoc.
1916, p. 114.
Swift, E. G.: Much of the liquid petrolatum offered has a kero-
sene odor and taste, and some samples darkened markedly with sul-
phuric acid.—Oil, Paint & Drug Rep. 1916, v. 90, No. 16, p. 46.
Terry, Rebert W.: All of the samples of liquid petrolatum ex-
amined were excellent in physical conditions. All of them were
colorless, without fluorescence. All were odorless when cold except
three. All were tasteless except one, which had a slightly oily taste.
Three samples contained traces of sulphur compounds and some of
the samples contained traces of unsaturated hydrocarbons.—Midl.
Drug. 1916, v. 50, p. 384-385.
Geyser, Albert C.: Notes on the physiology of medicinal petro-
Jeum oil and its use as a therapeutic agent—Am. Med. 1916, v. 22,
p. 106-108.
Barker, C.: Liquid paraffin is stated to be an excellent dressing for
burns of the first and second degree. It is not satisfactory in burns
of the third degree.—New. York M. J. 1916, v. 102, p. 1197.
PETROSELINUM.
Anon.: A short note giving information relative to the cultivation
of parsley in America.—N. A. R. D. J. 1916, v. 21, p. 703.
259
PETROXOLINUM LIQUIDUM, N. F.
Anon.: Notes on the preparation of liquid petroxolin.—N. A. R.
D. J. 1916, v. 23, p. 11.
Hilton, S. L.: The formula as changed in the N. F. IV works
satisfactorily when Russian liquid petrolatum is used, but is not as
satisfactory as the old formula when the American oil is used.—
Bull. Pharm. 1916, v. 30, p. 281.
PHENOL.
Rordorf, Helene: Phenol, when red in color, can be purified by
distillation from a 1.5-liter flask and an air condenser consisting
of a glass tube 1.5 meters long. Crystallization of the distillate
upon standing yields a phenol containing more than 90 per cent
C,H;OH.—Schweiz. Apoth.-Ztg. 1916, v. 54, p. 237-238.
Anon.: To prevent carbolic acid from becoming colored, it must
be freed from iron and be kept in iron-free containers (bottles
coated inside with paraflin are very good for this purpose).—Pract.
Drug. 1916, v. 34, No. 10, p. 35.
Forbing, John W.: A discussion of the selection and technique
of an appropriate method for the quantitative determination of
phenol. A modified Koppeschaar method is suggested as being the
most practical for the pharmacist.—J. Am. Pharm. Assoc, 1916, v. 5,
p. 166-169.
Krak, J. B.: Descriptions of methods for the determination of
phenol and salicylic acid in antiseptic gauze and cotton.—Chem.
Analyst, 1916, v. 17, p. 14-15.
Bramley, Arthur: A study of binary mixtures. Part L The
densities and viscosities of mixtures containing phenol.—J. Chem.
Soc. Lond. 1916, v. 109, p. 10-45.
Swift, E. G.: High-grade phenol is scarce. Much of that offered
is dark in color, has a foreign odor, and low melting point.—Oil,
Paint & Drug Rep. 1916, v. 90, No. 16, p. 46.
Congdon, Leon A.: Two samples of carbolic acid were rejected,
as they contained glycerin and were not of official strength.—Bull.
Kansas Bd. Health, 1916, p. 5.
Table showing some of the analytical results reported for phenol.
Number of samples—
p. 20.
Reporters. "y References.
Examined.) Rejected.
es =) os Z Pac ee’
ore Mo 2 18 4 | Bull. Indiana Bd. Health, 1916, vy. 19, p. 125.
onder MAG ORMP RE con ws cas oc 11 7 | Rep. Kansas Bd. Health, 1916, p. 133. :
Frary, i a | 6 | 3 | Rep. South Dakota F. & D. Com. 1916, No. 1,
‘ x | p. 149-150.
1] 1] Proc. Pennsylvania Pharm. Assoc. 1916, p. 116.
SS Sa eaeaaat 1 | 1 | Bull. Michigan D. & F. Dept. 1916, No. 244-217,
ahem —
260
Dubin, Harry.: A dissertation on the physiology of the phenols—
J. Biol. Chem. 1916, v. 26, p. 69-91.
Anon.: On the value of sodium sulphate as an antidote for phenol —
(carbolic acid) poisoning—J. Am. M. Assoc. 1916, v. 67, p. 535.
Wilbert, M. I.: The author points out the lack of value of aleohel
as an antidote for phenol.—J. Am. M. Assoc. 1916, v. 67, p. 233.
PHENOL IODATUM, N. F.
Ott and Roy: A report on the treatment of diphtheria carriers
with iodized phenol. A review of a number of cases.—J. Am. M.
Assoc. 1916, v. 66, p. 800-802.
PHENOL LIQUEFACTUM.
Congdon, Leon A.: Two samples of liquified phenol examined
were found to contain glycerin.—Bull. Kansas Bd. Health, 1916,
es iris | ea
Sayre, L. E.: Of four samples of liquified phenol examined, one
was adulterated and one was below standard.—Bull. Kansas Bd.
Health, 1916, p. 12.
Stinson, Ray: Eighteen of the sixty-three samples of liquified
phenol examined were below standard.—Proe. North Dakota Pharm.
Assoc. 1916, p. 111.
PHENOLPHTHALEINUM.
Puente, Carlos: A study of the chemistry and pharmacy of phe-
nolphthalein.—Farm. Espan. 1916, v. 48, p. 417-420, 433-435, 449-
451, 465-468, 482-486.
von Sztankay, A., and Geyer, C.: German Patent 286,020. A
process for the preparation of compounds of phenolphthalein with
alkali carbonates. These compounds are stated to be of therapeutic
value-——Chem. Abstr. 1916, v. 10, p. 1079.
Annibale, Ferraro: From experiments it is concluded that alco-
holic extracts should be diluted with about twice their volume of
water before titrating with phenolphthalein as an indicator. If
not, low results will be obtained.—Boll. chim.-farm, 1915, vy. 54,
p. 257-258
PHENYLIS SALICYLAS.
Levi, A.: Measurements of the thermal expansion of salol using a
dilatometer with mercury as the contact liquid are given. The specific
volume at the fusion temperature (40.6° C.) was found to be 0.774
for the solid phase and 0.846 for the liquid phase-——Chem, Abstr.
1916, v. 10, p. 1129.
Salkover, Benedict: A description of a quantitative method for
determining salol and acetanilid in mixtures of the two, also salol
and acetphenetidin in their mixtures. The method is based on the
tS he Te bh 2 ees rhb te Be ETE
%
‘a
261
difference in the solubility of these substances in petroleum ether.—
Am. J. Pharm. 1916, v. 88, p. 484-485,
Anon.: Attention is called to the fact that salol and euquinine are
physically incompatible, giving a damp, oily mass when mixed.—
Chem. & Drug. 1916, y. 88, p. 1057.
PHOSPHORUS.
Bridgman, P. W.: A report of investigations dealing with the
different allotropic forms of phosphorus. A white, two varieties of
red, and a black phosphorus are mentioned. Methods for producing
the black modification are discussed in detail_—J. Am. Chem. Soe.
1916, v. 38, p. 609-612; see-also A. Smits et al. Chem. Abstr, 1916, v.
10, p. 1480.
Lemkes, H. J.: The Dusart-Blondelot test for phosphorus was
found to be very sensitive and is recommended for toxicological work
if carried out at 50° to 60° C. with sufficient zine —Pharm. Weekblad.
1916, v. 53, p. 1496-1513.
PHYSOSTIGMA.
Sharp, Gordon: A history of Calabar bean and its introduction
into medicine.—Pharm. J. 1916, v. 96, p. 619-620.
Schneider, Albert: The measurements for physostigma starch are
given as “from 0.005 to 0.15 mm.” (5 to 150 microns), whereas none
of the granules exceed 85 microns in longest diameter.—Drug. Cire.
1916, v. 60, p. 692.
Polonovski, Max, and Nitzberg, Ch.: Alkaloids of the Calabar
bean. IV. A partial synthesis of eserine and geneserine.—Bull.
soc. chim. France, 1916, v. 19, p. 27-37 and 46-59; see also Chem,
P-Abstr. 1916, v. 10, p. 1165.
— Anon.: The ether-soluble alkaloidal content of one sample of
Calabar bean assayed was above standard.—Proc. Pennsylvania
Pharm. Assoc. 1916, p. 119.
PHYSOSTIGMINZ SALICYLAS.
Gifford, Harold: Physostigmine, in some form, is now generally
applied after homatropine refraction tests, but I have a decided
impression that it is not used as often or as thoroughly as it should
be.—J. Am. M. Assoc. 1916, v. 67, p. 118.
PILOCARPINZ HYDROCHLORIDUM.
McGuigan, Hugh: A study of the influence of atropine and pilo-
¢arpine on the glycogenic function. Pilocarpine, even in large
doses, does not produce a significant increase in blood sugar, but
causes a reduction after some hours.—J. Pharmacol, & Exper.
_ Therap. 1916, v. 8, p. 407-415.
262
PILOCARPUS.
Schneider, Albert: Pilocarpus powder is never “dark green,” as
described in the U. S. P. [X.—Drug. Cire. 1916, v. 60, p. 693.
E’we, G. E.: Of 13 samples of pilocarpus assayed, the alkaloidal —
content of 5 was above standard and 8 below.—Proc. Pennsylvania
Pharm. Assoc. 1916, p. 119.
PILULA.
Diekman, George C.: The number of official pills in the U. 8. P.
has been reduced from 14 to 7. The absence of the former array of
pills containing aloes is of special note.—Pract. Drug. 1916, v. 34,
No. 10, p. 25.
Danzel, L.: A powder consisting of a mixture of powdered licorice
root, powdered tragacanth, powdered almond oil soap, wheat groats
starch, sugar and hydrated magnesia is recommended as an ex-
cipient for making pills from liquids or viscous substances.—Drug.
Cire. 1916, v. 60, p. 486. )
De G. Peacock, J. C. and B. L.: An account of experiences with
the salol coating of pills.—Pacific Pharm. 1916, v. 9, p. 266-268.
Toplis, Wm. G.: Comments on the value of stearic acid as a
coating for enteric pills, with a description of the method of apply-
ing the coating.—Nat. Druggist, 1916, v. 46, p. 20.
PILULZ FERRI CARBONATIS.
Thum, John K.: In a review of the annual report of the chemical
laboratory of the American Medical Association, volume 8, atten-
tion is especially directed to the results obtained in the analyses of
commercial samples of Blaud’s pills—Am. J. Pharm. 1916, y. 88,
p. 504.
Wood, H. C., Jr.: Ten minims of the tincture of ferric chloride
contains less iron than a single Blaud’s pill—J. Am. M. Assee.
1916, v. 66, p. 1072.
Vanderkleed, C. E.: The samples of Blaud’s pills examined con-
tnined from 77 to 182 per cent of the claimed carbonate of iron
content.—J. Am. Pharm. Assoc. 1916, v. 5, p. 537.
PIPULZ FERRI IODIDL.
Dickman, George C.: It is difficult to conceive why an assay process
is not provided by the U.S. P. for pills of ferrous iodide. The faet
that these pills are to be coated with balsam of tolu does not en-
tirely insure them against decomposition.—Pract. Drug. 1916, v. 34,
No. 10, p. 25.
PIMENTA, N. F.
rary, Guy G.: All of the six samples of allspice examined were
of standard quality.—Rep. South Dakota F. & D. Com, 1916, No. 16,
p. 133-134,
Se ie ln hil be eel be
20rs yeeta ee et inp ee ere
a.
263
PINUS ALBA, N. F.
Anon.: A short note giving information relative to the production
and collection of white pine bark in America.—N. A. R. D. J. 1916,
v. 21, p. 916.
PIPER.
Memminger, Lucien: Notes on the cultivation and preparation of
pepper for the market in India.—Com. Rep. 1916, No. 26, p. 442.
_ Anon.: A note on the history of pepper.—Perf. & Ess. Oil Ree.
1916, v. 7, p. 48-49.
Salamon, M. S., and Seaber, W. M.: Analytical data obtained in
the analysis of white pepper are presented.—Chem. & Drug. 1916,
v. 88, p. 146-147.
Lagerheim, G.: A positive reaction of white pepper with Storch’s
reagent is stated to indicate adulteration. Storch’s reagent consists
of 2 per cent p—C;H,(NH.). and 1 per cent H,O, in aqeous solu-
tion.—Svensk Farm. Tidsskr. 1916, v. 20, p. 357-361.
Frary, Guy G.: Six of the 22 samples of pepper examined were
rejected because they were not of standard quality.—Rep. South
Dakota F. & D. Com. 1916, No. 16, p. 137-138.
PIX LIQUIDA.
Rusby, H. H.: The definition of tar as “a product obtained by the
destructive distillation of the wood of,” ete., presents a wretched
appearance when contrasted with that of the former edition, which
defined it as “an empyreumatic oleo-resin,” ete. So far as the pres-
ent definition is concerned, it applies equally well to the charcoal
that results from the distillation.—Drug. Cire. 1916, v. 60, p. 537.
PLUMBI ACETAS.
Smith, G. E.: A study of the factors controlling the reactions of
lead acetate and lead nitrate with disodium arsenate.—J. Am. Chem.
Soc: 1916, v. 38, p. 2014-2027.
PLUMBI CARBONAS, N. F.
Sharpe, F. H.: French Patent No. 479.219. A mechanical mixing
and reaction vessel for carbonating lead oxide is described.—Chem.
Abstr. 1916, v. 10, p. 2308.
PLUMBI OXIDUM.
Torossian, Gregory: A simple and rapid method for the approx-
imate quantitative determination of lead, with a table showing the
results obtained in the analysis of a number of lead compounds.—J.
Ind. & Eng. Chem. 1916, v. 8, p. 331,
264
PLUMBI OXIDUM RUBRUM, N. F.
Thompson, G. W.: In discussing the value of highly oxidized red —
lead, the author states that the ordinary product contains from 70
to 100 per cent of Pb,O,. The remainder consists principally of
litharge.—Chem. Abstr. 1916, v. 10, p. 2804.
Schaeffer, John A.: A description of a rapid method for the
analysis of red lead and orange mineral.—J. Ind. & Eng. Chem. 1916,
v. 8, p. 237-2388.
Milbauer, Jaroslav: A report of investigations to determine the
influence of the impurities in red Jead on its color when used in paints |
and varnishes.—Chem. Ztg@. 1915, v. 39, p. 858-859.
PODOPHYLLUM.
E’we, G. E.: Of nine samples of mandrake assayed the resin con-
tent of four was above standard and five below.—Proc. Pennsylvania
Pharm. Assoc. 1916, p. 119.
POTASSA SULPHURATA.
Roberts, J. G.: A lot of sulphurated potash in 1-pound cans was
rejected, as it had greatly deteriorated in strength.—Proc. Pennsyl-
vania Pharm. Assoc. 1916, p. 118.
POTASSII BITARTRAS.
Vecchia, L.: Notes on the cold extraction of potassium bitartrate
from grape marcs by Cambiagei’s method.—Chem. Abstr. 1916, v.
10, p. 2959.
Kantor: A report of results obtained in the application of Sander’s
picric acid method to the determination of Pueeot bitartrate.—
Chem. Abstr. 1916, v. 10, p. 439. .
Kunz, R.: Methndstt for the determination of total tartaric acid,
alkaline earth tartrates, potassium bitartrate, and free tartaric acid
in wine are described.—Arch. Chem. Mikros, 1915, v. 8, p. 51-61.
POTASSII BROMIDUM.
Beringer, George M.: The purity of potassium bromide has been
increased from 97 per cent absolute bromide in the eighth revision
to 98.5 per cent in the ninth revision—Am. Druggist, 1916, v. 64,
No. 8, p. 23.
Anon.: The appearance of adulterated potassium bromide on the
New York market is reported. The samples examined were found
to consist of about 90 per cent of granulated sugar.—West. Pennsyl-
vania Ret, Drug. 1916, February, p. 14.
Lilly, J. IK.: Some of the potassium bromide examined was found
to contain 10 per cent of potassium carbonate—Oil, Paint & Drug
Kep. 1916, v. 90, No. 16, p. 46.
265
Stinson, Ray: All of the 22 samples of potassium bromide exam-
ined were of U.S. P. standard.—Proec. North Dakota Pharm. Assoc.
1916, p. 112.
POTASSIT CHLORAS.
Taylor, Guy B., and Cope, W. C.: Experimental data showing
the hygroscopic properties of potassium chlorate and other sub-
stances used in the manufacture of detonators ave presented.—
Chem. Abstr. 1916, v. 10, p. 2799.
Salvadori, R.: An investigation of the action of ammonium
nitrate upon potassium chlorate. —Ann, chim. applicata, 1916, v. 6
p. 115-118. ;
Rowland, Floyd E.: An account of an unusual explosion in con-
nection with potassium chlorate—J. Ind. & Eng. Chem, 1916, v. 8
p. 517-518.
Squire, E, W.: A report of a case of poisoning in a 44 months
child due to the ingestion of potassium chlorate.—Brit. M. J. 1916,
v. 1, p. 450.
?
b
POTASSII CHLORIDUM, N. F.
Von Kolnitz, G. F.: U. S. Patent No. 1,201,396. A process for
the preparation of potassium chloride from greensand. The green-
sand mixed with CaCl, is heated to 900° C. in a reducing atmos-
phere. The KC] is recovered by Jeaching.—Chem. Abstr. 1916, v. 10,
Bp. 3142.
Amberg, S., and Helmholtz, HW. F.: The fatal dose of a 2 per
cent solution of potassium chloride Sten injected intravenously is
1 cubic centimeter for a guinea pig weighing 260 grams.—Chem.
Abstr. 1916, v. 10, p. 2598.
POTASSII FERROCYANIDUM.
Denigés, G.: An illustrated discussion of a new theory concerning
the structural formulas of the ferrocyanides.—Buli, soc. chim.
France, 1916, v. 19 and 20, p. 79-90.
POTASSIT HYDROXIDUM.
Rolland, Charles-Pierre: French Patent No. 478,372. An electro-
lytic process for the manufacture of potassium hydroxide from solu-
tions of potassium sulphate.—Chem. Abstr. 1916, v. 10, p. 2172.
Baxter, Gregory P., and Starkweather, Howard W.: A report of
investigations to determine the efficiency of calcium chloride, sodium
hhvdroxide, and potassium hydroxide as drying agents.—J. Am.
Chem. Soc. 1916, v. 38, p. 2038-2041.
266
“POTASSII IGDIDUM.
Riesenfeldt, E. H., and Bencker, F.: A report of experiments to—
determine the action of ozone on inorganic iodine compounds.—
Ztschr. anorg. Chem. 1916, v. 98, p. 167-201.
Stinson, Ray: All of the 21 samples of potassium iodide examined —
were of U. S. P. standard.—Proc. North Dakota Pharm. Assoc. 1916,
p.-112:
Wilcox, Reynold W.: A report of a case of acute potassium iodide
poisoning in a man 35 years of age-——New York M. J. 1916, v. 103,
p. 975-976.
POTASSIL NITRAS.
Congdon, Leon A.: Of 10 samples of saltpeter examined, 3 were
rejected for being of poor quality or adulterated.—Rep. Kansas Bd.
Health, 1916, p. 133.
POTASSIT PERMANGANAS.
Dewey, F. G.: Potassium permanganate is of no value in the
treatment of rattlesnake bite when administered internally. It is
a powerful oxidizing agent and if applied directly to the open
wound it will destroy the venom with which it comes in direct con-
tact—usually a very small amount.—J. Am. M. Assoc. 1916, v. 67,
p- 462.
POTASSIT SULPHAS, N. F.
Anon.: A reprint of the standards for potassium sulphate pro-
posed by the committee on unofficial standards.—J. Am. Pharm.
Assoc. 1916, v. 5, p. 88-89.
PRUNUS VIRGINIANA.
Anon.: A short note giving information relative to the production
and collection of wild cherry bark in America.—N. A. R. D. J. 1916,
y. 21, p. 1058.
Rusby, H. Ti.: Those in the best position for knowing the facts
now declare that Linnzeus was quite right in his description of the tree
yielding our official wild cherry bark under the name Prunus Vir-
givana, and that the supposition, so long prevalent, that he erro-
neously deseribed Prunus serotina is a mistake. The former should,
therefore, be given as the source of this drug—Drug. Cire. 1916, v.
60, p. 537.
Schneider, Albert: In the U. S. P. description of wild cherry,
no mention is made of the branching or forked bast cells —Drug.
Cire. 1916, v. 60, p. 693.
267
PULSATILLA, N. F.
Pilcher, Delzell, and Burman: A report of investigations to deter-
mine the action of pulsatilla on the excised uterus of the guinea
pig—J. Am. M. Assoc. 1916, v. 67, p. 409-492.
PULVIS ANTISEPTICUS, N. F.
Anon.: Notes on the preparation of soluble antiseptic powder.—
N. A. R.D. J. 1916, v. 22, p. 15.
QUASSIA.
Schneider, Albert: In the description of Surinam quassia, the
U.S. P. has neglected to mention the diagnostic sclerenchyma
cells—Drug. Cire. 1916, v. 60, p. 693.
Patch, E. L.: The ash of six samples of quassia examined
ranged between 2.2 to 8 per cent; the extractive between 3.3 and 7
per cent.—J. Am. Pharm. Assoc. 1916, v. 5, p. 543. —
QUERCUS, N. F.
Anon.: A short note giving information relative to the production
and collection of oak bark in America—N. A. R. D. J. 1916, v. 21,
p. 1056.
QUILLAJA, N. F.
Holmes, E. M.: Notes on the identity of a crystalline substance
obtained from a glycerin extract of quillaja. The substance was
found to be a calcium salt of an organic acid resembling quillaic
acid.—Pharm. J. 1916, v. 96, p. 220.
ee ee ee Se ee ae ee ee
QUININA.
Memminger, Lucien: A consular report on the output of quinine
in Madras Presidency.—Com. Rep. 1916, No. 261, p. 487-488.
Christensen, A.: A report of investigations to determine the effect
of chlorine on quinine in solution. Descriptions of a number of
the compounds formed are given.—Chem. Abstr. 1916, v. 10, p. 47
from Ber. deutsch. pharm. Gesellsch. 1915, v. 25, p. 256-281.
Filippi, Eduardo: In a discussion of chemical and physiological
methods for the identification of several allcaloids dissolved in the
same solvent, the author describes a method for separating quinine
from strychnine. The quinine is precipitated with Seignetti’s
salt.—Arch. farmacol. sper. 1916, v.-22, p. 120-130.
Scoville, W. L.: A note on the incompatibility of quinine with
aspirin. Quinotoxin is formed when the powders are moist as
aspirin is split into acetic and salicylic acids which latter react to
form the toxic compound.—Bull. Pharm. 1916, v. 50, p. 336,
ee ee ae ee ee ee mL ee,
268
E’we, G. E.: The water content of samples of quinine examined
was found to vary between 1.3 per cent to 14.3 per cent.—Proce.
Pennsylvania Pharm. Assoc. 1916, p. 116. ce
Vanderkleed, C. E.: The samples of quinine examined showed an
extreme variation in water content. Nine lots gave from 0 to 20
per cent of water—J. Am. Pharm. Assoc. 1916, v. 5, p. 543.
Barnard, H. E.: One sample of quinine examined was rejected.
Bull. Indiana Bd. Health, 1916, v. 19, p. 76. Ag
Harms, Herman: Of 72 samples of quinine capsules examined, 19°
were rejected for being of poor quality—Rep. Utah D. & F. Com.
1916, p. 96.
Boerner, F.: A test to demonstrate idiosyneracy to medicinal
doses of quinine is described.—J. Am. M. Assoc. 1916, v. 68, p. 907.
Smith, Maurice I., and Fantus, Bernard: A comparative study of
the pharmacological action of quinine and ethylhydrocuprein (opto-
chin).—J. Pharmacol. & Exper. Therap. 1916, v. 8, p. 53-74.
Morgenroth, J., and Tugendreich, J.: A study of the disinfectant
action of quinine and some of its derivatives on streptococci—Chem,
Zentralbl. 1916, v. 87, part 2, p. 506-507.
Tweedy, Sir John: A report on the use of solutions of quinine as —
a dressing for infected wounds.—Brit. M. J. 1916, v. 1, p. 11-12.
RENNINUM, N. F.
Graber, Howard E.: A discussion of the factors causing the
seasonal variation in coagulating power of milk, and of a corrected
method of testing vennin.—J. Ind. & Eng. Chem. 1916, v. 8, p. 909-
910.
Vanderkleed, C. E., and E’we, G. E.: Experiments on the assay of
rennin show that the time required by the enzyme for coagulation
of milk is inversely proportional to the amount of rennin employed.— _
J. Am. Pharm. Assoc. 1916, v. 5, p. 714-715. q
Swift, KE. G.: Rennin has almost disappeared from the market and —
the samples now offered for sale are usually low in strength.—Oil,
Paint & Drug Rep. 1916, v. 90, No. 16, p. 46.
E’we, G. E.: Six lots of rennin examined ranged between 1:27,750 |
and 1:46,250 in milk coagulating power on a 74-minute basis.—Proe. —
Pennsylvania Pharm, Assoc. 1916, p. 116.
RESINA.
Cohn, Georg: Descriptions of methods for the identification of
rosin and diets acid.—Chem.-Ztg. 1916, v. 40, p. 791-792. ‘
Merrill, E. C.: A report on the value of various resin tests—J. _
Assoc. Off. Agric. Chem. 1916, v. 2, part 2, p. 82-87; see also Chem.
Abstr. 1916, v. 10, p. 2384, :
269
~ Wutin: A method for the determination of rosin in gum resins is
| described. The author states that only approximate results are ob-
tamed. An abstract—C. U. C. P. Alumni J. 1918, v. 23, p. 219.
Reutter, Louis: Analyses showing the composition of two res-
mous masses used by the Incas in embalming their dead.—Schweiz.
Apoth.-Ztg. 1916, v. 54, p. 136-140.
Storandt, W.: The production of rosin in Prussia. A general re-
_ view.—Chem. Abstr. 1916, v. 10, p. 1442 from Seifensieder-Ztg.
| 1916, v. 43, p. 149.
RESINA JALAPA.
Holmes, E. M., and Passmore, F. W.: As a source of jalapin (resin
_ of jalap insoluble in ether), the Brazilian jalap is twice as valuable
as the Vera Cruz jalap, since it contains twice the standard quantity
- of resin required by the Ph. Brit.-Pharm. J. 1916, v. 41, p. 671.
Snyder, J. Paul: The U. S. P. VIIT directions for determining
the chloroform-soluble matter in resin of jalap are indefinite. The
~ Pharmacopeeia should state definitely the amounts of the sample and
_ chloroform to be used, the method to be employed, and the length of
time the resin should be treated with the solvent—J. Am. Pharm.
Assoc. 1916, v. 5, p. 34-37.
Roberts, J. G.: One sample of resin of jalap examined was not of
U. S. P. quality, as it contained 2.15 per cent more chloroform-sol-
ublé matter than the U. S. P. standard of not more than 35 per
cent.—Proc. Pennsylvania Pharm. Assoc. 1916, >. 116.
Vanderkleed, C. E.: One sample of resin of jalap examined was
not completely soluble in five times its weight of ammonia water.—
J. Am. Pharm. Assoc. 1916, v. 5, p. 540.
RESINA PODOPHYLLI.
Tanzen, Heinrich: After employing a number of different meth-
ods for the evaluation of podophyllin, the author concludes that the
method of the Ph. Ndl. is the most practical for the pharmacist.—
Chem. Zentralbl. 1916, v. 87, part 1, p. 998 from Arch, Pharm. 1915, v.
254, p. 44-49.
RESINA SCAMMONTI/®.
Beringer, George M.: The U. 8. P. TX directs that scammony root
be used in the preparation of the resin because virgin scammony is
no longer obtainable—Am. Druggist, 1916, v. 64, No. 8, p. 24.
Rusby, H. H.: It would have been a very wise action on the part
of the revision committee to have intreduced the resin of Mexican
-scammony under a separate title instead of leaving it out entirely,
as is now the case.—Drug. Cire. 1916, v. 60, p. 537.
270
Roberts, J. G.: In three lots of resin of scammony_ examined,
46.54, 71.06, and 76.07 per cent of ether-soluble matter was found.—
Proc. Pennsylvania Pharm. Assoc, 1916, p. 117.
RESORCINOL.
Krauskopf, F. C., and Ritter, G.: A description of a color reaction —
with cobalt chloride for the detection of resorcinol in the presence
of catechol, quinol, and pyrogallol—J. Am. Chem. Soe. 1916, v.
28, p. 2182-2187.
Wolff, Jules: Descriptions of biochemical reactions which permit
of differentiating between the three isomeric diphenols—pyrocate-
chol, hydroquinone, and resorcino!l.—Compt. rend. soc. biol. 1916, y.
79, p. 1019-1020. |
RHAMNUS CATHARTICA, N. F.
Tunmann, O.: Observations on the analysis of rhamnus barks.
Methods for distinguishing between drugs of different species are
discussed.—J. Chem. Soc. Lond. 1916, vy. 110, p. 504 from Apoth.-
Zig. 1915, v. 30, p. 642.
RHEUM.
Anon.: Notes on the cultivation of rhubarb for medicinal use.—
Northwestern Druggist (The), 1916, v. 17, No. 5, p. 36-37, No. 6,
p- 36-37, No. 7, p. 39-40. P
Tschirch, A., and Ruzzkowski, M.: A report on the value of samples
of rhubarb obtained from the Altai Mountains. An assay by the
Tschirch method showed 3.20 per cent of oxymethyl-anthraquinone.
An abstract.—C. U. C. P. Alumni J., 1916, v. 23, p. 12.
Lilly, J. K.: One Jot of rhubarb examined consisted of the rha-
pontic variety and was not U. S. P.—Oil, Paint & Drug Rep. 1916,
No. 16, p. 46.
ROSA GALLICA.
Rusby, Hi. H.: Several shipments of “rose petals” have been
received which consisted of the entire body with calyx attached—
J. Am. Pharm. Assoc. 1916, v. 5, p. 543.
RUBUS, N. F.
Anon.: A short note giving information relative to the production
and collection of blackberry bark in America.—N, A. R. D. J. 1916,
v. 21, p. 1058.
SACCHARUM.
Milius, H. C., and Sehoorl, N.: Notes on the attempts to define
sugars from an analytical chemical standpoint—Pharm. Weekblad,
1916, v. 53, p. 1249-1262,
)
271
Clarence, J. F.: An account of the sugar industry of Jaya.—Chem.
Abstr. 1916, v. 10, p. 1281 from Intern. Sugar J. 1916, v. 18, p. 80-82.
W. J. P. P.: A book review of a small volume by Felix Langen on
the methods employed in the refining of sugar.—Chem. Weekblad,
1916, v. 13, p. 1229,
De Sornay, P.: Experiments in which sodium phosphate was used
as a clarifier indicate that this salt may be used with advantage in
the manufacture of white sugar.—J. Soc. Chem. Ind. 1916, v. 34. p.
916.
Haworth, Walter N., and Law, James: Researches to determine
the structure of sucrose——J. Chem. Soc. Lond. 1916, v. 109, p. 1314-
1325. :
Anon.: Observations on the action of the cyanides of the alkalies
and of the alkaline earths on different varieties of sugar.—Siidd.
Apoth.-Ztg. 1916, v. 56, p. 8.
Maquenne, L.: Data showing the presence of reducing substances
other than invert sugar in commercial sugars. These so-called sec-
ondary reducers are stated to be due to poor manufacture.—Compt.
rend. Acad. sc. 1916, v. 162, p. 277-282.
Owe, W. L.: Some observations on the deterioration of sugars
in storage. The article deals with the relation of moisture content
and the presence of impurities to the growth of microérganisms.—
Chem. Abstr. 1916, v. 10, p. 1281 from Louisiana Planter, 1916, v.
56, p. 173-174 and 188-190.
Rockey, D. W.: The technique of the g-naphthol test for sugar is
described in detail, also illustrated.—Chem. Abstr. 1916, y. 10, p.
1605 from Sugar, 1916, v. 18, No. 2, p. 70-71.
Pellet, H.: A discussion of the causes of error in the determina-
tion of reducing sugar by the use of cupro-potassic solutions —Ann.
chim. anal. 1915, v. 20, p. 123-125.
Pellet, H.: Notes on Steuerwald’s modification of the double po-
larization method for the estimation of sugar, with some general
observations in inversion.—Chem. Abstr. 1916, v. 10, p. 1280.
Glaser, G.: A correction table for sugar chemists, together with
various technical formulas.—Chem, Abstr. 1916, v. 10, p. 2159.
Gore, H. C.: A note on the occurrence of sucrose in American
grapes.—J. Ind. & Eng. Chem. 1916, vy. 8, p. 333.
Waterman, H. I.: Experimental data showing the influence of age
and low temperature on the saccharose content of potatoes.—Chem.
Weekblad, 1916, v. 13, p. 122-127.
Anon.: In a review of recent reports on the use of sugar as a
dressing for wounds it is stated that Dr. G. Magnus, of Marburg, as
a result of experiments made in the service of Prof. Koenig, recom-
272
mended sugar as a practical and inexpensive dressing for wounds.—
J. Am. M. Assoc. 1916, v. 67, p. 825. 4
Simonds, J. P.: A report of experiments bearing on the usefulness |}
of sugar in the treatment of wounds infected by Bacillus perfrin-
gens.—Compt. rend. soc. biol. 1916, v. 79, p. 906-908. :
SACCHARUM LACTIS. |
Dietrich, J. D.: U. S. Patent No. 1,201,027. A method for the ~
preparation of lactose solution from whey.—Chem. Abstr. 1916, v. 10,
p. 3135,
Wechselmann, W.: The bad results obtained with lactose in the
test for kidney efficiency is due to the presence of microérganisms.
If the sugar is rendered absolutely sterile, all after-reactions are_
eliminated.—Berlin, klin. Wehnschr. 1916, v. 53, p. 84-85.
SALVIA.
Chase, Benjamin F.: A consular report of the wild sage industry
of the Adriatic.—Com. Rep. 1916, No. 99, p. 364-366.
SANGUINARIA.
Scoville, W. L.: The alkaloidal content of 10 lots of blood root ex-
amined varied from 1.77 to 7.01 per cent. Seven of the 10 samples
contained 5 per cent or more—dJ. Am. Pharm. Assoc. 1916, v. 5,
p. 537.
Anon.: The alkaloidal content of 15 samples of sanguinaria as-
sayed was above standard.—Proc. Pennsylvania Pharm. Assoe. 1916,
pe LEY: :
SANTALUM ALBUM, N. F.
Briggs, C. H.: Some notes on sandalwood, its assay, yield of oil,
and changes in the oil during distillation.—J. Ind. & Eng. Chem,
1916, v. 8, p. 428-429.
SANTALUM RUBRUM.
Lilly, J. K.: Two lots of red saunders examined were low in color
content and were probably partially extracted—Oil, Paint & Drug
Rep. 1916, v. 90, No. 16, p. 46.
SANTONINUM.
Holmes, E.M.: Artemisia pauciflora (Ledebour), Weber, is given —
as the source of this drug. This is differently quoted by Hanbury,
who gives (Pharmacographia, I], p. 886) A. maritima, var. A.
paucifiora (Weber), quod Ledebour, as a synonym of Artemisia mari-
tima, var. Stechmanniana, Which is the name given in the B. P.—
Pharm. J. 1916, v. 97, p. 485.
273
Trendelenburg, Paul: The action of santonin and its derivatives
pon the musculature of worms, and remarks on the action of oil of
henopodium.—Chem. Abstr. 1916, v. 10, p. 497 from Arch, exp. Path.
harm. 1915, v. 79, p. 190-217.
SAPO.
_ Abraham, Joseph: A short eas review of soap manufac-
ure—J, Am. Pharm. Assoc. 1916, v. 5, p. 293-303.
Lecoq, Raoul: The manufacture of sodium and potassium soaps on
n industrial scale. A descriptive review—Bull. sc. pharmacol. 1916,
. 23, p. 225-246,
Wrisley, G. H.: Comments on the Krebitz process of soap making
nd glycerol recovery.—J. Ind. & Eng. Chem. 1916, v. 8, p- 732-733 ;
e also Chem. Abstr. 1916, v. 10, p. 2411.
Bergo: In order to save fat in the manufacture of soap, the in-
orporation in the cake of such fat solvents as benzene, carbon tetra-
chloride or naphtha is recommended.—Chem. Abstr. 1916, v. 10, p.
78.
Stratton, S. W.: Specifications for soaps and methods for testing
the same.—Cire. Bur. Stand. 1916, No. 62, p. 1-25.
Lenher, Victor, and Buell, Mary V. R.: A report of some studies
on soap solutions. ery: Ind..& Eng. Chem. 1916, v. 8, p. 701-703.
Slack, H. F.: A discussion of the aecnisbabiete of the raw ma-
terials and finished products of soap manufacture——Perf. & Ess. Oil
Rec. 1916, v. 7, p. 326-333.
Dickson, M. R.: Descriptions of practical laboratory methods for
he analysis of soap. Hiibl’s method for the determination of rosin
is recommended.—Chem. Abstr. 1916, v. 10, p. 2411.
Rosenberg, Louis, and Lenher, Victor: Descriptions of analytical
methods for the examination of soap powders.—J. Ind. & Eng. Chem.
1916, v. 8, p. 716-719.
Newington, F. H.: A description of a method for the determina-
tion of free caustic alkali in soap. The method is based upon the
rinciple of “salting out” the soap from its aqueous solution by
means of sodium sulphate.—J. Soc. Chem. Ind. 1916, v. 35, p. 95-96,
Terry, P. B.: A description of a procedure for the determination
of glyceroi in soaps.—Chem. Analyst, 1916, v. 16, p. 13-23.
Slack, H. F.: A description of a new method for the determination
of the fatty acids in soap.—Pharm. J. 1916, v. 41, p. 696.
Whitney, cael D. V.: Some of the commercial soaps on the market
abeled U. S. P. are not up to the standard of purity. A sample
tested was nat completely soluble in water and contained animal
fats—Proc. Missouri Pharm. Assoc. 1916, p. 29-30.
110095°—19——18
274
Scoville, Wilbur L.: The U. S. P. chemical tests for soap have
been made more stringent for the purpose of excluding all but ai
olive oil soap. The restrictions on moisture content are expected to
give more uniform results in the preparation of soap liniment and
soap plaster.—Bull. Pharm., 1916, v. 30, p. 364.
Patch, E. L.: The samples of powdered soap examined were foun
to be well within the U. S. P. limits for moisture content as the
contained only from 1 te 6 per cent. Two of the samples were only
partially soluble in hot alcohol and solidified on cooling—J. Am.
Pharm. Assoc. 1916, v. 5, p. 544.
Shorter, S. A., and Ellingworth, S.: The emulsifying action of
soap—a contribution to the theory of detergent action—Proc. Roy.
Soc. Lond. 1916, Sec. A, v. 92, p. 231-247; see also Perf. & Ess. Ot
Rec. 1916, v. 7, p. 224-226.
Dickinson, G. K.: Notes on the antiseptic properties of soap.—
Med. Rec. 1916, v. 89, p. 556-558.
SAPO MOLLIS.
Scoville, Wilbur L.: The cotton seed oil soap of the U. S. P. LX is 4
a little firmer and not as easily soluble as linseed oil soap, but other- —
wise is very satisfactory.—Bull. Pharm. 1916, v. 30, p. 364.
SARSAPARILLA.
Wood, H. C., jv.: In a discussion of the pharmacologic action of
sarsaparilla, it is stated that the therapeutic value of the latter de-
pends on the saponins which it contains. Further, that these saponins —
have no effect on the system which is not common to all of this group —
of vegetable principles. By virtue of the nausea which they pro-
duce through their irritant action on the mucous membranes, they
may increase the secretions of the bronchi and the skin and may
therefore be of value in the treatment of acute bronchitis.—J. Am,
M. Assoc. 1916, v. 66, p. 1070-1071.
Anon.: Comments on the doubtful virtues of sarsaparilla—Pharm, —
J. 1916, v. 96, p. 297-298.
se ilciealenabicadbaniatne Pee 4S ee
SASSAFRAS. | ;
Koch, Felix J.: A short account of the gathering of sassafras in ©
the vicinity of Cincinnati, Ohio.—Drug. Cire. 1916, vy. 60, p. 751.
Anon.: A short note giving information relative to the production —
and collection of sassafras bark in America.—N. A. R. D. J. 1916, ~
v. 21, p. 1056,
é
SCILLA.
t
Holmes, KE. M.: Urginea maritima (Linné), Baker, is given ‘as the —
botanical source. This name is used in Pharmacographia, although —
Urginca Scilla, Steinheil, the name adopted in the B. P., has the”
275
priority, Linnzus having put it in the genus Sci//¢, which has tri-
quetrous seeds, while those of Urginea are flat and discoid.—Pharin.
J. 1916, v. 97, p. 485.
Schneider, Albert: Powdered squill can hardly be designated as
“light yellow” in color, though it is light yellowish-brown.—Drug.
Cire. 1916, v. 60, p. 693.
SCOPARIUS, N. F.
Sharp, Gordon: Notes on the introduction of scoparius in medi-
cine and on its pharmacological and therapeutic actions.—Pharm.
J. 1916, v. 96, p. 348.
peere : A reprint of the standards for broom top proposed by the
ae on unofficial standards.—J. Am. Pharm. Assoc. 1916, v.
d, p. 89.
SCOPOLAMINE HY DROBROMIDUM.
Leyton, Albert and Helen: From experiments on the prevention
of anaphylaxis in guinea pigs, it is concluded that dextro- and levo-
scopolamine are equally active on the central nervous system, but
only the dextro form affects the peripheral organs.—Chem. & Drug.
1916, v. 88, p. 1172.
Joachimoglu, Georg: A comparison of the action of scopolamins
and atropine on the cat eye. Scopolamine was found to be approxi-
mately tenfold as active as atropine.—Berlin. klin. Wehnschr. 1915,
_ v. 52, p. 910; see also Chem. Abstr. 1916, v. 10, p. 783.
_ Editorial: The behavior of the uterus and other organs toward
gee a. tate A sits of several recent papers.—
SCUTELLARIA, N. F.
Pilcher, Delzell, and Burman: A report of investigations to deter-
mine the action of skullcap on the excised uterus of the guinea pig.—
J. Am. M. Asscc. 1916, v. 67, p. 490-492.
SENECIO, N. F.
_ Pilcher, Delzell, and Burman: A report of investigations to deter-
mine the action of life root on the excised uterus of the guinea pig.—
J. Am. M. Assoe. 1916, v. 67, p. 490-492.
SENNA.
Schneider, Albert: In the U. S. P. description of the sennas, the
diagnostic size and form of the ech wa cells is not mentioned.—
Drug. Cire. 1916, v. 60, p. 693.
216
Ruedinger, H.: A description of a method for obtaining senna
leaves free from resin.—Boll. chim.-farm. 1916, v. 55, p. 40; see also
Chem. Abstr. 1916, v. 10, p. 1907.
Congdon, Leon A. De lots of senna examined were rejected for
not complying with the BASE: Belg sce. —Bull. Kansas Bd.
Health, 1916, v. 12, p. 7.
Lilly, J. K.: One lot of senna examined contained sand and stones
up to 9 per cent.—Oil, Paint & Drug Rep. 1916, v. 90, No. 16, p. 46.
SERUM ANTIDIPHTHERICUM.
Heinemann, P. G.: Report of the committee of the laboratory sec-
tion of the American Public Health Association on standard methods
for preparing diphtheria antitoxin.—Am. J. Public Health, 1916,
v. 6, p. 751, (52.
Zingher, Abraham: A description of a modification of Roemer’s
method for the determination of small amounts of diphtheria anti- ©
toxin in blood sera.—J. Infec. Dis. 1916, v. 19, p. 556-564.
Busson, Bruno, and Léwenstein, Ernst: A report of experimental
studies on the immunity conferred by diphtheria toxin-antitoxin
mixtures.—Chem. Abstr. 1915, v. 10, p. 217.
SERUM ANTITETANICUM PURIFICATUM.
Wintz, M.: A report of investigations concerning the antitoxin
content of the serum of tetanus patients. The amount was found to
be too small to permit of its being used therapeutically —Chem.
Abstr. 1916, v. 10, p. 1053 from Miinch. med. Wehnschr. 1915, v. 62,
p. 1633-1635,
Lowy, O.: Studies on tetanus immunity in man. Only a few
tetanus convalescents showed the presence of specific immune bodies.
Jn other cases the immune bodies are either not present or are elimi-
vated rapidly —Chem. Abstr. 1916, v. 10, p. 2109 from Wien, klin.
Wehnschr. 1915, v. 28, p. 1288-1290,
SINAPIS ALBA.
Ttolmes, E. M.: White mustard is referred to Sinapis alba, Linné,
but Sinapis nigra to Brassica nigra (Linné), Koch, although Druce
has pointed out (Yearbook of Pharmacy, 1898, p. 462) that Brassica
sinapiodies, Roth, is an earlier name. Why the Sinapis alba should
not be referred to the genus Brassica, as is now usual, is not evident.—
Pharm. J. 1916, v. 97, p. 485.
Penau: A dese ce of a method for the assay of mustard seed,
An abstract.—C, U. ck Alumni J. 1916, v. 23, p. 169. i
van Leersum, na An explanation of the laxative action, of
white mustard seed. The hydrogen sulphide formed from the seed
277
is stated to be the laxative principle—J. Pharmacol. & Exper.
Therap. 1916, v. 8, p. 285-296; see also Chem. Abstr. 1916, v. 10, p.
2003.
Lybing, J.: A note on the adulteration of mustard seed with the
seeds of Brassica juncea—Svensk farm. Tidskr. 1916, v. 20, p. 79-81.
Rusby, H. H.: All mustard imported has undergone a very re-
markable improvement as to cleanliness and freedom from weed
-seeds.—J. Am. Pharm. Assoc. 1916, v. 5, p. 541.
Frary, Guy G.: Of 23 samples of ground mustard examined, one
contained added wheat flour and another contained starch and
tumeric.—Rep. South Dakota F. & D. Com. 1916, No. 16, p. 131-132.
SINAPIS NIGRA.
Schneider, Albert: Ground black mustard is never “ greenish
brown ” in color as described in the U. S. P. [1X.—Drug. Cire. 1916,
vy. 60, p. 693.
SODA CUM CALCE, N. F.
Guareschi, J.: A literary review in which the history, chemistry,
and uses of soda lime are discussed in detail—Chem. Abstr. 1916,
v. 10, p. 25.
Kelley, G. L.: A description, illustrated with a diagram, of an
improved soda-lime tube for use in the determination of carbon
dioxide.—J. Ind, & Eng. Chem. 1916, v. 8, p. 1038-1039.
SODII ACETAS.
Gnesotto, T.. and Fabris, C.: A presentation and discussion of
data pertaining to the thermal constants of hydrated sodium
' acetate-—Chem. Abstr. 1916, v. 10, p. 1128.
SODIT ARSENAS.
Smith, G. E.: A study of the factors controlling the reactions of
- disodium arsenate with lead nitrate and lead acetate-—J. Am. Chem.
Soc. 1916, v. 38, p. 2014-2027.
SODII BENZOAS.
Lewis, H. B., and Carr, W. B.: A report of researches to deter-
mine the influence of sodium benzoate on uric acid elimination.—J.
Biol. Chem. 1916, v. 25, p. 13-20.
SODII BICARBONAS.
Astrue, A., and Cambe, J.: Experimental data showing the inter-
action of sodium bicarbonate with certain salts, especially bismuth
salicylate—J. pharm. et chim. 1916, v. 14, p. 803-306.
278
Rogers, Leonard: A report of studies to determine the value o
injections of sodium bicarbonate in the prevention of uremia.—Chem.
Abstr. 1916, v. 10, p. 2112.
SODII BORAS.
Lythgoe, Hermann C.: Of two samples of borax examined, on
was found to be adulterated—Rep. Massachusetts Bd. Health, 1916,
p. 400.
SODIT BROMIDUM.
Beringer, George M.: The purity of sodium bromide has been in-
creased from 97 per cent absolute bromide in the Eighth Revision to
98.5 per cent in the Ninth Revision.—Am. Druggist, 1916, v. 64, No. 3,
p. 22.
SODIIT CACODYLAS.
Cole, H. N.: A discussion of the value of sodium cacodylate in
the treatment of syphihs. The author agrees with Nichols and
others in that he states it is of no value.—J. Am. M. Assoc., 1916, v.
67, p. 2012-2013; Rep. Therap. Res. Com., 1916, v. 5, p. 200-204.
Neiman, L. A.: Notes on the intravenous use of sodium cacodylate
in the treatment of syphilis——Am. J. Clin. Med., 1916, v. 23, p.
07-408.
Anon.: Venarsen, prepared by the Intravenous Produets Co., is a
simple solution containing sodium cacodylate with mercuric iodide
and sodium iodide.—J. Am. M. Assoc., 1916, v. 66, p. 978.
SODIT CARBONAS MONOHYDRATUS.
Beringer, George M.: On account of the high price of potassium
salts, due to the war, the U. S. P. IX directs that sodium carbonate —
may be substituted for potassium carbonate in the solution of mag-
nesium citrate, rhubarb preparations, etc.—Am. Druggist, 1916, vy.
G4, No. 8, p. 24.
Clark, A. H.: A presentation of data on the keeping qualities of
sodium sulphite and sodium carbonate.—Drug. Cire. 1916, v. 60, p. —
096.
Colson, A.: Notes on contradictions between calculated and ob-
served solubilities of certain sodium salts. The discordance found
for sodium carbonate is not explained.—Chem. Abstr., 1916, v. 10, —
Davin
Jénecke, Ernst: A report on the determination of the melting —
points of monohydrated sodium carbonate and other salts by means
of an electrically heated pressure apparatus.—Chem. Abstr., 1916, v.
10, p. 143.
279
SODIL CHLORIDUM.
Lohman, Clifford: A description of a method for preparing pure
sodium chloride. The potassium is removed by means of platinic
chloride.—Chem. News, 1916, v. 114, p. 53.
Caldwell, H. V.: Laboratory control in salt refining. The article
includes a description of the methods of testing for impurities.—Am.
Tood J., 1916, v. 11, p. 621-622.
Rabe, Rudolph F.: A report on the physiological action of sodium
chloride administered in physiological doses—J. Am. Inst.
Homoeop., 1916, v. 8, p. 1013-1015.
Shearer, Creswell: Experimental data showing the toxic action of
dilute, pure sodium chloride solutions on the meningococeus.—Proe,
Roy. Soc., Lond., 1916, Sec. B, v. 89, p. 440-443.
Ostrovsky, S. E.: The elimination of sodium chloride in sear-
let fever. Weiss’s method for the quantitative determination of
sodium chloride in the urine was found to be accurate. An ab-
stract.—J. Am. M. Assoc., 1916, v. 66, p. 1666.
SODII CITRAS.
Salant, W., and Wise, L. E.: An investigation of the pharmaco-
logical action of sodium citrate.—J. Biol. Chem. 1916, v. 28, p. 27.
Satterlee and Hooker: As anticoagulants for use in the transfusion
of blood, sodium citrate and metaphosphate are the only substances
exhibiting desirable characteristics. Both of these salts, however,
have texic properties which demand consideration of the quantities
that can be safely employed for the purpose of transfusion.—J. Am,
M. Assoc. 1916, v. 66, p. 618-624.
Garbat, A. L.: The sodium citrate method of transfusion is not to
be considered in any way dangerous because of the sodium citrate
employed. <A 0.25 per cent solution of the salt has been found to be
satisfactory for preventing coagulation.—J. Am. M. Assoc. 1916,
v. 66, p. 1543.
SODII GLYCEROPHOSPHAS,
Anon.: In a review of the U. S. P. IX regret is expressed for the
admission of calcium and sodium glycerophosphates, as their thera-
peutic efficiency is in doubt at the present time.—J. Am. M. Assoc.
1916, v. 67, p. 764.
Hegland, J. M. A.: A cheap method of preparing sodium glycero-
phospate is stated to consist of evaporating to dryness a mixture of
446 parts of Na,P,O, and 776 parts of 25 per cent H,PO,, and then
heating this residue at 190° C. with anhydrous glycerin —Pharm.
Weekblad, 1916, v. 53, p. 1645-1648,
280
Anon.: A review of the work which has been done to determine —
the structure of sodium glycerophosphate.—Pract. Drug. 1916, No. 7, —
p- 39.
Bailly, O.: An explanation of the mechanism of the reaction be-
iween tribasic sodium phosphate and the a-chlor substitution product
of glycerin.—J. pharm. et chim. 1916, v. 18, p, 155-159.
Keulemans, N.: A note on the preparation of a 50 per cent solu- —
tion of sodium glycerophosphate.—Pharm. Weekblad, 1916, v. 53,
p- 259-260.
SODII HYDROXIDUM.
Rather, J. B.: A report on methods for testing sodium hydrox-
ide.—J. Assoc. Off. Agric. Chem. 1916, v. 2, p. 38-41.
E’we, G. E.: Some of the sodium hydrate examined was strictly
U.S. P. in quality, but was labeled “ crude” and was in a granular
powder.—Proc. Pennsylvania Pharm. Assoc. 1916, p. 117.
Baxter, Gregory P., and Starkweather, Howard W.: A report of
investigations to determine che efficiency of calcium chloride, sodium
hydroxide, and potassium hydroxide as drying agents.—J. Am.
Chem. Soe. 1916, v. 38, p. 2038-2041.
SODII HYPOPHOSPHIS.
Marriott, W. M.: From experimental data, the author concludes
that there is no reliable evidence to show that the hypophosphites
exert any physiological effect or that they act as foods—J. Am. M.
Assoc. 1916, v. 66, p. 486-488; Rep. Therap. Res. Com. 1916, v. 5,
p. 103-111.
SODII IODIDUM.
de Matta, A. A.: A discussion of sodium iodide from a pharma-
ceutical and medical standpoint. Descriptions of tests for identity
and purity are included. An abstract——J. Am. M. Assoc. 1916, v. 67,
p. 1337.
Vanderkleed, C. E.: One lot of sodium iodide examined assayed
but 95.2 per cent of NaI, the low assay being due to moisture.—J. Am,
Pharm. Assoc. 1916, v. 5, p. 544.
Giintelberg, E.: A report of thermodynamical experiments to de-
termine the affinity in the reaction KC]O,+NaI=KI+NaClO,—
Chem. Abstr. 1916, v. 10, p. 1463.
SODII NITRAS.
Anon.: A book review calls attention to a volume by A. Hartwig
entitled Die Saltpeterindustrie Chiles und thre weltwirtschaftliche
Gedeutung.—Chem. Abstr. 1916, vy. 10, p, 373. |
281
_ Taylor, Guy B., and Cope, W. C.: Data relating to the hy groscopic
} properties of the nitrates of sodium, potassium, and ammonium.—
Chem. Abstr. 1916, v, 10, p. 2799 from Met. Chem. Eng. 1916, v. 15,
| p. 140-143,
SODII PERBORAS.
_- Liebknecht, O.: U. S. Patent No. 1,200,739. A method for the
| preparation of a stable sodium perborate is described.—Chem. Abstr.
_ 1916, y. 10, p. 3142.
Berthelot, Albert: A note on the dangers of using impure sodium
| perborate in medicine and surgery. Special mention is made of the
effect of the presence of carbonate.—Répert. pharm. 1916, v. 28, part
1, p. 2382_233.
SODII PHOSPHAS.
Street, John Phillips: Eleven samples of sodium phosphate were
examined. While all samples showed a fair degree of purity, partial
_ efflorescence of the salt was noted in some cases.—Rep. Connecticut
Agric. Exper. Sta. 1916, part 4, p. 256.
SODII PHOSPHAS EFFERVESCENS.
| Street, John Phillips: All of the three samples of effervescent
_ sodium phosphate examined showed a deficiency in carbonate prob-
ably due to decomposition as a result of exposure to damp air.—Rep.
| Connecticut Agric. Exper. Sta. 1916, part 4, p. 257.
SODII SALICYLAS.
Lami, P.: A description of a laboratory method for preparing
sodium salicylate from sodium carbonate.—Boll. chim.—farm. 1916,
, Y. 55, p. 199.
Terry, R. W.: A sample of sodium salicylate contained an excess
. of moisture. As the salt is very hygroscopic, the high moisture con-
_ tent was probably due to the fact that the bottle had been opened
_ previous to analysis—Proc. Ohio Pharm. Assoc. 1916, p. 59.
- Wanderkleed, C. E.: Two samples of sodium salicylate examined
assayed 97.2 and 98.4 per cent instead of the U. S. P. 99.5.—J. Am.
_ Pharm. Assoc. 1916, v. 5, p. 544.
Hill, J. Rutherford: A discussion of the incompatibilities resulting
from the prescribing of iodine and sodium salicylate in the same mix-
~ ture——Pharm. J. 1916, v. 96, p. 397.
Editorial: In a review of an article by Blankenhorn, sodium
salicylate 1 is stated to be a valuable drug. It is official and cheap and
is quite equal to the substitutes that have been offered for it from
time to time.—J. Am. M. Assoc. 1916, v. 66, p. 362.
282
Scott, R. W., and Hanzlik, P. J.: Researches on the physiologi
effects of the salicylates. When given in full therapeutic doses they
produce albuminuria.—J. Am. M. Assoc. 1916, v. 67, p. 1838-1841;
Rep. Therap. Res. Com. 1916, v. 5, p. 185-199.
SODII SULPHAS.
Carles, P.: A description of a method for detecting the presence o
arsenic in sodium sulphate.—J. pharm. et chim. 1916, v. 13, pp. 219-
991: see also Répert. pharm. 1916, v. 28, part 1, p. 148; Ann. chim
analyt. 1916, v. 21, p. 116-117; Farm. Espan. 1916, v. 48, p. 328.
Kohn-Abrest, E.: An explanation of the reaction which takes
place between one acid and Na,SO,.10H,O.—Ann, Falsif. 1916 B,
v. 9, p. 68-69; see also Soc. Chem. Ind. 1916, v. 35, p. 597.
ie nold, W. J.: Comimeus on ne use of soditun sulphate in dysen-
tery and infantile di
Anon.: A discussion of the es of aoe culphete as an anti-.
dote for phenol (carbolic acid) poisoning—J. Am. M. Assoe. 1916,
y. 67, p. 535.
SODIIT SULPHIS EXSICCATUS.
Clark, A. H.: A presentation of data on the keeping qualities of
sodium sulphite and sodium carbonate—Drug. Cire. 1916, v. 60,
p. 396.
SODIL THIOSULPHATE.
Sander, A.: A discussion of a modification of Bodnar’s method for
the determination of thiosulphate in the presence of sulphite.—
Ztschr. anal. Chem. 1916, v. 55, p. 349.
SPARTEINA SULPHAS.
Zeigler, W. H.: From a study of the pharmacological action of
spartine sulphate, it is concluded that this alkaloidal salt is not a car-
diac stimulant, but a depressant to both the heart and the respira- —
tion.—Southern M. J. 1916, v. 9, p. 671-676.
SPIGELIA.
Roberts, J. G.: One lot of spigelia examined contained a few for-
eign roots, but was considered of normal quality—Proe. Pennsyl-
vania Pharm. Assoc. 1916, p. 117.
SPIRITUS.
Diekman, George C.: The number of spirits in the U. S. P. has
been reduced from 20 to 15, and a further reduction in number might
very properly have been made.—Pract. Drug. 1916, v. 34, No. 10,
p. 20.
283
SPIRITUS AETHERIS COMPOSITUS, N. F.
‘Dickman, George C.: The deletion of compound spirit of ether is
justified on the grounds that it is difficult or even impossible to obtain
ethereal oil of uniform quality—Pract. Drug. 1916, v. 34, No. 10,
p. 25.
SPIRITUS AETHERIS NITROSL.
Dickman, George C.: It is difficult to conceive why a working
formula for the preparation of spirit of nitrous ether is retained in
the Pharmacopeeia, as pharmacists, with very few exceptions, do not
manufacture this article. At the very best it is a difficult process to
follow, and the product obtained in most cases will not meet the re-
quirements.—Pract. Drug, 1916, v. 34, No. 10, p. 25.
Kebler, L. F., Palkin, S., re Ewi ing, C. O.: A presentation of
experimental ters obtained in investigations to determine the stabil-
ity of the spirit of nitrous ether—J. Am. Pharm. Assoc. 1916, v. 5,
p. 514-516.
Bachman, Gustav, and Turner, D. D.: Analytical data showing the
rate of decomposition of spirit of nitrous ether when stored under
different conditions——Proc. Minnesota Pharm. Assoc. 1916, p. 156-
139; see also D. D. Turner, p. 139-141.
Engelhardt, H., and Winters, O. E.: Experimental data are pre-
sented showing the superiority of the Dietze potassium chloride
method, as adopted by the Dutch pharmacopeeia, over the U. S. P.
method for the assay of the spirit of nitrous ether. —J. Am. Pharm.
Assoc. 1916, v. 5, p. 1327-1329.
Turner, D. D.: A table showing the quality of 14 samples of spirit
of nitrous ether collected during a trip throughout the northwest
portion of the United States.—Drug. Cire. 1916, v. 60, p. 268.
Table showing some of the analytical results reported for spirit of nitrous ether.
Number of samples—
Reporters. Fey References.
Examined.| Rejected.
ia he oO ES
(EMMI ein ods ada ss<saKa wc 59 | 50 Proc. Maryland Pharm. Assoc. 1916, p. 84-94,
20 ons Toes 7 ES BBE 9 | 7 | Proce. Minnesota Pharm. Assoc. 1916, p. 211.
LUG Sc SEE 53 37 | Bull. Vermont Bd. Health, 1916, v. 17, No. 2.
Wi setae nscmrcceseccse an 3 3 | Rep. Wyoming D. F. & O, Com. 1916, v.2, No. 7,
p. 33, 34.
Congdon, Leon A............. 6 4} Rep. Kansas Bd. Health, 1916, p. 54,133, __
Frary, Guy Co Sie Se 20 | 14 | Rep. South Dakota F. & D. Com. 1916, No. 16,
p. 148.
Hostmann, Jeannot..........- 10 | 4 | Proc. New Jersey Pharm. Assoc. 1916, p. 77.
PE CR EE Ae cose meen nn 3 3 | Bull. California Bd. Bealth; ay y. 11, p. 648.
Lythgoe Hermann C......... 110 | 56 | Rep. Massachusetts Bd. Health, 1916, p. 450.
McGill, 2 4 a Bee eee 85 | $1 Bull. Lab. Inl. Rev. Dept. C anada, 1916, No. 339,
| p.4.
i 2 8 a ae 1 | 1 | Bull. Kansas Bd, Health, 1916, p.9. __
Todd: LY Oe ee 12 | 8} Bull. Michigan D. & F. Dept. 1916, Nos. 244-747,
p. 20; Nos. 250-251, p. 16; Nos. 252-255, p. 19.
a CC LLL
284.
SPIRITUS AMMONIA.
Diekman, George C.: The spirit of ammonia was used so little
and varied so much in ammonia content, even when carefully kept, —
that its deletion must be considered justifiable-—Pract. Drug. 1916, |
vy. 34, No. 10, p. 25.
SPIRITUS AMMONIZ AROMATICUS.
Editorial: Aromatic spirit of ammonia is an old-fashioned com-
plex mixture; its reputation has little scientific basis. Whatever
effect it may have is probably psychic, to a considerable degree at
Jeast. Such effect might be expected from the irritation of the nasal
mucosa by the ammonia and the flavor and odor of the lemon, lav-
ender and nutmeg oils. The physical effect, if any, is probably due
to the alcohol, though the ammonium carbonate and combined am-
monia may have some restorative action by their irritation of the
gastric mucosa or by their neutralization of nauseating acids mm the
stomach.—J. Am. M. Assoc. 1916, v. 67, p. 65.
Wood, Horatio C.: Any stimulating effect which may be observed —
after the oral administration of aromatic spirits of ammonia is due
either to a psychic effect or to its local irritant action on the gastric
mucosa, just as the irritation of the mucous membrane of the nose by
ammonium carbonate, in the form of smelling salts; may reflexly
excite the medulla. Jf the stimulant action of ammonium carbonate
administered by the mouth is due to its local irritant effect:on the
mucous membrane of the stomach, it is evidently a matter of minor
importance whether the irritant is alcoholic or ammoniacal or a com-
bination.—J. Am. M. Assoc., 1916, v. 67, p. 231.
Lanski, J.: Aromatic spirits of ammonia is not devoid of useful-
ness. A whiff of it, by virtue of its physical properties, resuscitates
the depressed patient for a moment, at least, which is more than we
get from digitalis or strychnine. The manner and intensity of this
resuscitation may be of service in giving us an insight into the
nature and extent of the depression. It is therefore deserving of a
place even in a restricted pharmacopoeia, not as a life-saver but as
a useful agent.—J. Am. M. Assoc. 1916, v. 67, p. 828.
Congdon, Leon A.: Of four samples of aromatic spirits of am-
monia examined, three were rejected.—Rep. Kansas Bd. Health, 1916,
p. 133.
Lea, E. J.: Four samples of aromatie spirits of ammonia examined
were below the standard.—Bull. California Bd. Health, 1916, v. 11,
p. 648. ,
Vanderkleed, C. E.: Some of the samples of aromatie spirit of
ammonia examined were deficient in carbonate and in ammonia
water One lot which contained three times too much ammonia Wis
evidently prepared from stronger ammonia water instead of am-
monia water.—J. Am. Pharm. Assoc. 1916, v. 5, p. 544,
285
SPIRITUS ANISI.
Lythgoe, Hermann C.: Of 45 samples of spirit of anise examined,
19 were adulterated.—Rep. Massachusetts Bd. Health, 1916, p. 450,
SPIRITUS CAMPHORZA.
Scoville, Wilbur L.: The fact that artificial camphor is optically
mactive prevents its being used in the preparation of the spirit,
which is assayed by a Beririsiairic method.—Bull, Pharm. 1916, v.
30, p. 362.
Beringer, George M.: For the determination of camphor in the
_ spirit of camphor, the U. S. P. now specifies the polariscope method.
_ As very few pharmaceutical laboratories have this expensive appara-
tus, it is thought that this test is more academic than practicable, and
that its observance will be largely confined to State laboratories —
Am. Druggist, 1916, v. 64, No. 8, p. 24.
Kollo, Constantin: A method for the quantitative determination
of camphor in spirit of camphor consists of precipitating the camphor
with lead acetate, dissolving the precipitate in a weighed amount
of ether, and calculating die! quantity of camphor from the increase
in weight of the ether solution—Chem. Zentralbl, 1916, v. 87, part
2. p. 112.
Rustung, G.: An account of experimental researches on the quan-
titative estimation of foes in spirit of camphor.—Norges Apotek.
Tidsskr. 1916, v. 24, p. 17-22; see also C. Y1strup Dahle, p. 125-127.
Anon.: A eit itict = a method for the eterrtiseatiion of the
camphor content of the spirit—Apothecary, 1916, v. 13, No. 2, p. 36.
Krauss, Ludwig: A table showing the results obtained in the
quantitative estimation of camphor in a large number of druggists’
samples of spirit of camphor. The difference in the behavior of
natural and synthetic camphor toward Hiibl’s solution is pointed
out.—Sitidd. Apoth.-Ztg. 1916, v. 56, p. 248-249.
Table showing some of the analytical results reported for spirit of camphor.
Number of samples—
Reporters. SSS | References.
Examined.} Rejected.
= 44 6 | Connecticut D. & F. Com. 1916, p. 19.
Ante Sil eee 40 8 | Balt Vermont Bd. Health, 1916, v. 16, No. 3; v.
“San ea |. 17, Noeeg2
Dy ee eee 1 1 | a Fy yoming D, F F. & O. Com. 1916, v. 2, No. 7,
eee 15 1 | Bull. diand Bd. Health,1916, v. 19, p. 63 and 76,
pee ia OFY 7 3 | Rep. Kansas Bd. He alth, 1916, D. on —
‘rar i, eas é4 23 | Rep. South Daketa F. & D. Com. 1916, No. 16,
RAP MTTLV Gr thy oinioo oe O 140-141. ne : pi At
ate 15 2 Proc. New Jersey Pharm. Assoc. 6, p.
Lsthgoe, Hermann ¢ aie 135 23 | Rep. Massachusetts Bd. Health, 1916, p. 450.
McGill, A.... “ape | 168 42 | Bull. Lab. Inl. Rev. Dept. Canada, 1916, No. 344,
a ee Vere
Stins 123 68 | Proc. North Dakota Pharm. Assoc. 1916, Whe
So He Hey 2 ae ei enlia 30 9 | Bull. Michigan D. & F. Dept. 1916, No. te 247,
(ioe 2
p. 20; No. 248-249, p. 10; No, 252-255, p. 19.
286
SPIRITUS FRUMENTI.
Anon.: The National Association of Retail Druggists at their last
convention passed a resolution favoring an official standard for —
whisky and brandy in order that inferior pele for medicinal pur-
poses may be avoided.—N. A. R. D. J. 1916, vy. 22, p. 1851.
Beringer, George M.: A detailed eee of the pharmacopaaa’
standards for whisky and brandy.—J. Am. Pharm. Assoc. 1916, v. 5,
p. 54-65.
Doerschuk, A. N.: A discussion of the wisdem of deleting whisky
—
ty Sie? i IIe oe
and brandy from the U. 8. P—Proc. Missouri Pharm. Assoc. 1916, —
p. 92-95.
Beringer, George M.: An abstract of the report of the referee on
whisky and brandy.—Pharm. Era, 1916, v. 49, p. 59-62.
SPIRITUS GAULTHERIA.
Anon.: Of 21 samples of spirit of gaultheria examined, 1 was re-
jected for being of poor quality —Off. Insp. Maine Agric. Exper. Sta.
1916, app. p. 28.
Anon.: Of 18 samples of essenee of wintergreen examined, 1 was
adulterated —Bull. Vermont Bd. Health, 1916, v. 17, No. 2
Lythgoe, Hermann C.: Of nine samples of spirit of wintergreen
examined, one was adulterated—Rep. Massachusetts Bd. Health,
1916, p. 450.
SPIRITUS LIMONIS, N. F.
Redfern, E. L.: Notes on the analysis of nonalcoholie lemon and
orange extracts.—J. Ind. & Eng. Chem. 1916, v. 8, p. 421.
Anon.: Six samples of spirit of lemon examined were found to be
genuine.—Rep. Massachusetts Bd. Health, 1916, p. 450.
SPIRITUS MENTHAE PIPERITZ.
Thompson, H. L.: A description of methods for the determination
of menthyl acetate and total menthol in the spirit of peppermint.
Data obtained in the analysis of a number of samples of spirit by the
author’s methods are presented in the form of tables —Am. J. Pharm.
1916, v. 88, p. 803-308.
Table showing some of the analytical results reported for spirit of peppermint.
Number of s: Ss |
Reporters. eee ees = References.
Examined.| Rejected. |
RIGA Fe oon Stew can wnphinia’l aed Gai 31 | 5 | Off. tet Maine Agric. Exper. Sta. 1916, app.
». 24-2
WD. ain daa namie poeta dpeten<s 40 16 Bull ng scien Bd. Health, 1916, No. 3, v. 17,
Congdon, Leott A... .c...-0e- 4 2 aoe ‘Finwx Bd. Health, 1916, p. 133.
Prary, Guy @i...c0ssccsesees 42 7 Rep. South Dakota F. & D. Com. 1916, No. 16,
p. 149.
Hostmann, Jeannot..........- | 10 | 4 Proc. New Jersey Pharm. Assoc. 1916, p. 78.
ythgoe, Hermann C......... 194 42. Rep. Massachusetts Bd, Health, 1916, p. 450.
TRICE, NV IIIT OF oda ec ans eece ns 35 13°) Rep. New Jersey Dept. Health, 1916, p. 72.
SE Gee Se Mistas pa Ne adage he tobe A 11 | 4 sull, Michigan D. & F. Dept. 1916, Nos, 244-247,
p. 20; Nos. 248-249, p. 10, Nos. 252-255, p. 19.
7
287
SPIRITUS MYRCIA COMPOSITUS, N. F.
Anon.: The change in title from “ Spiritus Myrciw” to “ Spiritus
Myrcie Compositus ” is commendable. The deletion of the synonym
“bay rum” is a mistake, because barbers and barber’s supply houses
can now sell anything they desire as bay rum.—N. A. R. D. J. 1916. v.
29, p. 939. |
Tice, William G.: Of 98 samples of spirit of myrcia examined. 18
were below standard.—Rep. New Jersey Dept. Health, 1916, p. 72.
SPIRITUS VINI GALLICL
Beringer, George M.: A detailed discussion of the pharmacopeial
standards for whisky and brandy.—J. Am. Pharm. Assoc. 1916, v. 5,
p. 54-65. Additional references are given under Spiritus Frumenti.
STAPHISAGRIA.
Anon.: In a discussion of the use of delphinium as a remedy for
pediculosis, formulas for making a variety of larkspur preparations
are given.—J. Am, M. Assoc. 1916, v. 66, p. 913.
STRAMONIUM.
Rusby, H. H.: Stramonium is now made to include Datura Tatula,
on the ground that the latter contains an equal amount of alkaloid,
the question of the identity and properties of such alkaloid being dis- .
regarded.—Drug. Circ. 1916, v. 60, p. 537.
Holmes, E. M.: Under the name stramonium, Datura Tatula is
official, as well as Datura Stramonium.—Pharm. J. 1916, v. 97, p. 485.
Brill, Harvey C.: Analytical data showing the alkaloidal content
of the various organs of Datura alba.—Philippine J. Se. 1916, v. 11,
sec. A, p. 257-260.
Sivoloboy: Researches on the volatile odoriferous constituents of
Datura Stramonium. Methyl and ethy] alcohols, together with small
portions of aldehydes, ketones, and esters, were identified. The alde-
hydes comprise acetaldehyde and probably formaldehyde, propalde-
hyde, isobutylaldehyde, and another aldehyde of considerably higher
boiling point. Acetone and another ketone of higher boiling point
were found and esters of acetic and formic acids.—Perf. & Ess. O11
Rec. 1916, v. 7, p. 51 from Journ. Russ. Phys. Chem. Soe, 1915, v. 47,
p. 1561. :
Anon.: Data showing the alkaloidal content of South African
stramonium leaves as compared with those from Europe, India, and
Egypt. The analyses were made at the Imperial Institute-—Chem.
& Drug. 1916, v. 88, p. 868.
288
Anon.: Attention is called to the recurrence at the use of Yanthium
strumarium as an adulterant for stramonium.—Pharm. J. 1916, va
43, p. 404.
Anon.: Of 18 samples of stramonium leaves assayed, the mydriatie .
alkaloidal content of 11 was above standard and 7 below.—Proe.
Pennsylvania Pharm. Assoc. 1916, p. 119.
Roberts, J. G.: Of 22 lots of stramonium leaves assayed, only 2
lots, containing 0.22 and 0.23 per cent respectively, of alkaloids were
NO Mens. tke a, the other 20 lots 0.25 to 0.48 per cent of alkaloids —
were found.—Proc. Pennsylvania Pharm. Assoc. 1916, p. 117.
Swift, E. G.: Five lots of stramonium leaves examined contained
from 0.27 to 0.57 per cent of alkaloids——Oil, Paint & Drug Rep. 1916,
vy. 90, No. 16, p. 46.
STRONTII CARBONAS, N. F.
De Coninck, W. O.: A discussion of some reactions of the car-
bonates of calcium, strontium, barium, zinc, and manganese——Ann.
chim, analyt. 1916, v. 21, p. 131-133.
STRONTIT SALICYLAS.
Blankenhorn, M. A.: From experiment, it is concluded that stron-
tium salicylate possesses no advantage over other salicylates as a
therapeutic agent——Rep. Therap. Res. Com. 1916, v. 5, p. 76-80;
J. Am. M. Assoc. 1916, v. 66, p. 331-333.
E’we, G. E.: Twe lots of strontium salicylate examined showed
cloudiness in the U.S. P. test for barium but were otherwise U. 8. P.—
Proc. Pennsylvania Pharm. Assoc. 1916, p. 117.
STROPHANTHINUM.
Rowe, L. W.: Observations on the variability in the activity of
strophanthin, with particular reference to ouabain.—J. Am. Pharm.
Assoc, 1916, v. 5, p. 1183-1187.
Klein, Karel: A discussion of experiments relative to the cumu-
Jative action of strophanthin.—Chem. Abstr. 1916, v. 10, p. 937.
STROPHANTHUS.
Rusby, H. H.: Strophanthus is at present so defined as to permit
the use of either Strophanthus Kombe or Strophanthus hispidus, a
procedure which is, to say the least, rash in view of our present
knowledge.—Drug. Cire. 1916, v. 60, p. 537.
Holmes, E. M.: Stropanthus hispidus is now recognized as official,
as well as 8. Hombe. ‘This is a distinct advantage, as S. hispidus is
not likely to be mixed with other species; and although the similar
289
seed of S. Arnoldianus might be substituted for it, the colour test
readily distinguishes them.—Pharm. J. 1916, v. 97, p. 485.
Sharp, Gordon: Historical notes on the chemistry, pharmacology,
and therapeutics of strophanthus.—Pharm. J. 1916, v. 96, p. 347-318.
Hatcher, Robert: A presentation of experimental data showing
that the oil of strophanthus is not the constituent of strophanthus
seed which produces emesis—J. Am. Pharm. Assoc. 1916, v. 5, p.
157-162.
Clampett, G. W.: Of three samples of strophanthus leaves exam-
ined, the strophantin content ranged from 1.4 to 6.5 per cent.—Proe.
Texas Pharm. Assoc. 1916, p. 80.
Lantier: On the treatment. of cardiac affections with “l’intrait de
strophanthus ”—a powdered extract of the drug.— Bull. se. pharmacol.
1916, v. 23, p. 36-46.
STRYCHNINA.
Patch, E. L.: One sample of strychnine alkaloid examined was
dark in color and contained an excess of brucine—J. Am. Pharm.
Assoc. 1916, v. 5, p. 544.
Chase, C. S., and Schlomovitz, E. H.: A discussion of the so-called
stimulating action of strychnine. The designation of strychnine as
a stimulant is cited as an example of the dangerous misuse of words.—
J. lowa Med. Soc. 1916, v. 6, p. 215-219.
- Smith, Maurice J.: A study of the action of strychnine in certain
types of cardiac irregularities.—J. Pharmacol. & Exper. Therap.
1916, v. 9, p. 365-399.
Hatcher, R. A., and Smith, M. I.: Researches on the elimination of
strychnine by the kidneys.——J. Pharmacol. & Exper. Therap. 1916,
v. 9, p. 27-41.
Anon.: California quail have been found to be comparatively im-
mune to the action of strychnine, whereas ground squirrels are par-
ticularly susceptible-—Chem. & Drug. 1916, v. 88, p. 408.
STRYCHNINAE NITRAS.
Fillippi, Eduardo: An investigation of the chemical and physio-
logical properties of strychnine nitrate in a solution containing an
excess of a quinine salt. Both the chemical and physiological actions
are obscured.—Arch. farmacol. sper. 1916, v. 22, p. 120-180 through
Chem. Abstr. 1916, v. 10, p. 2781.
STYRAX.
Henge, M.: Researches on styrax. I. The detection of coniferous
resin acids (abietic and pimaric acids).—Ber. deutsch. chem. Gesell-
- sch., 1916, v. 49, p. 1622-1632; see also J. Soc. Chem. Ind. 1916, v.
49, p. 1622.
110095°—19——19
290
Kafuku, K.: Researches on the constituents of the volatile oil of
liquidambar of Formosa. The oil consists chiefly of terpenes, among
which are camphene, «-pinene, dipentene, and probably phellandrene —
und nopinene. It also contains traces of aldehydes or ketones par-
tially unrecoverable from bisulphite compounds.—J. Chem. Ind. |
Japan, 1916, v. 19, p. 516 through Chem. Absir, 1916, vy. 10, p.
23862: Ste -
SULPHUR SUBLIMATUM.
Lamoreaux, W. F.: U. S. Patent No. 1,169,726. A method of
extracting iii from sulphur oxides by the use of carbon 1 is de-
scribed.—Chem. Abstr. 1916, v. 10, p. 957.
Gaubert, Paul: A desoniptiog of a new crystalline form of sulphur
obameneterbina as spherolites in helicoidal spirals—Compt. rend. acad.
se. 1916, v. 162, p. 554-556. ;
Wolf, R. B.: In discussing chemical testing in sulphite pulp work, —
the analysis of sulphur is considered——Chem. Abstr. 1916, v. 10,
p. 2403. q
Belatti, M., and Finazzi, L.: Data concerning the heat of solution of —
sulphur in carbon disulphide are presented. The values were found —
to vary from —11.89 to —11.55 calories—Chem. Abstr, 1916, v. 10,
p. 1126.
Fonzes-Diacon: A discussion of the methods of adulterating sul-
phur and the means for detecting the same-—Ann. Falsif. 1916, v. 9,
p. 333-339.
Smith, W.: A description of a method for the estimation of sele-
nium in sulphur.—Chem. News, 1916, v. 114, p. 44-45.
Paul, L.: Experimental data relative to the incorporation of sul-
phur in vaseline at different temperatures are given.—Chem, Abstr.
1916, v. 10, p. 251. ; |
Anon.: A review of a book by G. Martin entitled Sulphurie Acid
and Sulphur Products.—Nature, 1916, v. 97, p. 118.
Neumaijer: A report of poisoning ina soldier who rubbed his body )
with sulphur for the removal of lice.—Pharm. Weekblad, 1916, v. 53,
p- 38.
SUMBUL.
Heyl, Frederick W., and Hart, Merrill C.: A report of researches
to determine the constituents of sumbul reot. Sucrose, levulose, be-
taine, an acid resin, a phytosterol ; acetic, butyric, tiglic, angelic, oleic,
linolic, cerotic, palmitic, and stearic acids; a phytosterolin, a neu-
tral resin, a glycosidic resin, and a volatile oil were among the con-
stituents isolated and identified.—J. Am. Chem. Soc. 1916, v. 38,
p. 432-446.
Du Paul, Armand: A report of an analysis of a sample of sumbul
root.—Apothecary, 1916, v. 18, No. 5, p. 22.
291
SUPRARENALUM SICCUM. -
Ogota, Akira: From experimental researches, the author concludes
that the red precipitate formed when bichromates are added to a
solution of adrenalin is nothing but chromium dioxide. An ab-
_ stract.—J. pharm et chim. 1916, v. 14, p. 144-145,
Cosentino, G. G.: A study of the effect of subcutaneous and in-
_ travenous injections of adrenalin upon dogs.—Arch. farmacol. sper.
1916, v. 21, p. 400-410.
Auer, J., and Gates, Frederick L.: Investigations relating to the
absorption of adrenalin after intratracheal injection.—J. Exper. M.
1916, v. 28, p. 757-772.
Stewart, G. N., and Rogoff, J. N.: A report of experiments to de-
termine the influence of certain factors, especially emotional dis-
turbances, on the epinephrine content of the adrenales—J. Exper. M.
1916, v. 24, p. 709-738.
Harrower, Henry R.: Notes on the action of adrenalin when given
by mouth.—New York M. J. 1916, v. 104, p. 893-895.
Brown, E. D.: Observations on the effect of epinephrine on the
medullary centers.—J. Pharmacol. & Exper. Therap. 1916, v. 8, p.
195-203.
Muto, K.: A report on the action of epinephrine in its relation to
the secretion of sweat.—Chem. Abstr. 1916, v. 10, p. 2006 from Mitt.
med. Fak. Univ. Tokyo, 1916, v. 15, No. 2.
Schapiro, F.: An investigation of the action of digitalis alone
and in combination with epinephrine and thyroid upon the heart
of Rana esculenta——Biochem. Ztschr. 1916, v. 73, p. 1-14; see also
Chem. Abstr. 1916, v. 10, p. 1680.
Meltzer, S. J.: In the treatment of infantile paralysis at the New
York Throat, Nose and Lung Hospital, 2 cubic centimeters of a
1: 1000 epinephrine hydrochloride solution was administered (intra-
spinal injection) every six hours for many days without the slightest
harm.—J. Am. M. Assoc. 1916, v. 67, p. 461.
SYRUPI, N. F.
Diekman, George C.: The U. S. P. TX contains 21 syrups besides
simple syrup. This isa reduction of 7 from the number found in the
U.S. P. VIII. The deleted syrups are in the main unimportant ones
and a number of them have found a resting place in the N. F. I1V.—
Pract. Drug. 1916, v. 34, No. 10, p. 26. }
West, R. M.: Researches on the determination of moisture in
syrups by the calcium carbide method—J. Ind. & Eng. Chem
1916, v. 8, p. 31-35.
KKeulemans, N.: A note on the preparation of maltose syrup.—
Pharm. Weekblad, 1916, v. 53, p. 257-259.
292
SYRUPUS.
Mayer, Joseph L.: In a second paper on the inversion of cane
sugar in syrup, the author confirms the observations made in his
earlier work, namely, that inversion is more rapid in syrup made
by the cold process ean when made by the hot process. —J. Am.
Pharm. Assoc. 1916, v. 5, p. 712.
SYRUPUS ACACIA.
Luce, E.: A discussion of the methods of Rocques and Sellier, and
Bellier for the quantitative determination of acacia in syrup of
acacia. Bellier’s method was found to be most suitable for use in
practice.—Ann. Falsif. 1916, v. 9, p. 227-2313 see also J. pharm. et
chim. 1916, v. 14, p. 138-19.
SYRUPUS ACIDI HYDRIODICI.
Beringer, George M.: The strength of syrup of hydriodic acid has
been changed from 1.19 grams of HI in 100 cubic centimeters to 1.3
to 1.45 grams in 100 mils.—Am. Druggist, 1916, v. 64, No. 8, p. 23.
Anon.: Notes on the preparation of syrup of hydriodic acid.—N. A.
R. D. J. 1916, v. 22, p. 429.
SYRUPUS AMMONII HYPOPHOSPHITIS, N. F.
Smith, F. A. Upsher: A formula for syrup of ammonium hypo-
phosphite, accompanied by directions for its preparation, is given.—
Northwestern Druggist (The), 1916, v. 17, No. 3, p. 49.
SYRUPUS BROMIDORUM, N. F.
Anon.: Notes on the preparation of syrup of the bromides.—
N. A. R. DJ. 1916; v. 23, ar i4ls.
SYRUPUS CALCIS.
Diekman, George C.: It is unfortunate that the syrup of lime has
been dropped entirely. It is used extensively and a standard should
have been provided for it.—Pract. Drug. 1916, v. 34, No, 10, p. 26.
SYRUPUS ERIODICTYI AROMATICUS, N. F.
Anon.: As a clarifying agent in the preparation of the aromatic
syrup of yerba santa, magnesium carbonate, precipitated caleium
phosphate or kieselguhr is reeommended.—N. A. R. D. J. 1916, v. —
Z1,-p; (12,
ee ee ee ee ee ee ee eee ee el il Cai i | fee 7
293
SYRUPUS FERRI IODIDI.
Toplis, Wm. G.: A description of a modified U. S. P. process for
the rapid preparation of syrup of iodide of iron—Proe. Pennsylvania
Pharm. Assoc. 1916, p. 243.
Anon.: Of 30 samples of syrup of ferrous iodide examined, 4 were
_ found to be below standard.—Rep. Connecticut D. & F. Com. 1916,
p. 19.
SYRUPUS HYPOPHOSPHITUM COMPOSITUS, N. F.
Anon.: A working formula for the preparation of the compound
_ syrup of hypophosphites.—N. A. R. D. J. 1916, v. 21, p. 1172.
Wood, H. C., jr.: A review of the hypophosphite theory, with the
statement that an unbiased study of the evidence must lead to the
conclusion that any therapeutic value in the compound syrup of
hypophosphites is due to the sugar it contains.—J. Am. M. Assoe.
1916, v. 66, p. 1068-1069.
SYRUPUS MORPHINAE ET ACACIAE, N. F.
Frangois, Maurice, and Luce, E.: A report of researches relative
to the determination of morphine in solutions of morphine hydro-
chloride and the syrup of morphine of the French Codex.—Ann.
Falsif. 1916, v. 9, p. 83-90; see also J. pharm. et chim. 1916, v. 13,
p. 152-155.
SYRUPUS PRUNI VIRGINIANAE.
Diekman, George C.: The change in the formula for the prepara-
tion of wild cherry syrup will meet with the approval of the phar-
macist. It is very similar to that given in the U. 8. P. VII, which
has been followed by many pharmacists in the past, even though a
different process was directed to be employed in the U. S. P. VIII.—
Pract. Drug. 1916, v. 34, No. 10, p. 26.
SYRUPUS RUBI IDAEI, N. F.
Blomberg, C.: Analytical data showing the saccharose content of
raspberry syrup when prepared according to different methods and
stored under different conditions—Pharm. Weekblad, 1916, v. 53,
p. 337-341.
SYRUPUS SARSAPARILLZ COMPOSITUS.
Anon.: A formula for the preparation of the syrup is presented
which requires the use of crude drugs instead of the fluid extracts
as directed in the U. S. P.—N. A. R. D. J. 1916, v. 21, p. 1120,
294
“SYRUPUS SENEGE.
.
Mueller, Bertha: A description of an improved method for the
preparation of syrup of senega. The fluid extract of senega is
diluted with water and macerated with purified tale before adding
the sugar—Am. J. Pharm. 1916, v. 88, p. 241-243.
SYRUPUS SENN AROMATICUS, N. F.
Anon.: The formula for the preparation of the aromatic syrup of
senna is faulty in that only about one-half of the sugar can be
brought into solution—N. A. R. D. J. 1916, v. 22, p. 273.
Anon.: Detailed directions for the preparation of the aromatic
syrup of senna are given and a revised formula is presented.—N. A,
R. D. J. 1916, v. 21, p. 1065.
TALCUM PURIFICATUM.
Anon.: A short note on the production of soap stone and tale in the ~
United States.—Oil, Paint & Drug Rep. 1916, v. 90, No. 21, p. 33.
Gottschalk, Alfred L. M.: A consular report giving the locations
of the various tale deposits in Brazil—Com. Rep. 1916, No. 298,
p. 1081.
Rohland, P.: The adsorption capacity of talcum, kaolin, and clay.
A comparative study.—Apoth.-Ztg. 1916, v. 31, p. 40-42; see also
Chem. Abstr. 1916, v. 10, p. 1258.
Malt, F.: A study of the chemical disintegration of talc, chlorite,
and biotite——Chem. Abstr. 1916, v. 10, p. 442.
TARAXACUM.
Small, James: Facts and fancies about dandelions——Pharm. J.
1916ews Oe, ce 157-158.
Patch, E. L.: One sainple of powdered dandelion root examined
yielded 45 per cent of ash. The usual yield is 9 per cent.—J. Am.
Pharm. Assoc. 1916, v. 5, p. 538.
Roberts, J. G.: Over one-third of 13 lots of dandelion root ex-
amined were of inferior quality or were adultcrated.—Proc. Pennsyl-
vania Pharm. Assoc. 1916, p. 112.
TEREBINTHINA, N. F.
Herty, Charles T.: An illustrated paper deseribing the turpen-
tine industry in the Southern States.—J. Franklin Institute. 1916,
v. 181, p. 339-367.
Henrich, F.: Notes on the collection of turpentine oleoresin in
Germany.—Chem.-Ztg. 1916, v. 40, p. 673-674.
295
Wislicenus, H.: A description of improvements in the methods for
the collection of oleoresins—Chem.-Ztg. 1916, v. 40, p. 559-560.
Troup, R. S.: Data showing the physical and chemical properties
of the oleoresin and oil of turpentine obtained from Indian Pins
longifolia—Perf. & Ess. Oil Ree. 1916, v. 7, p. 243-245, 280-282.
Casey, F. W.: Of five samples of turpentine examined, four were
rejected.—Bull. Michigan D. & F. Dept. 1916, No. 252-255, p. 19.
Congdon, Leon A.: One sample of wood turpentine examined was
reje ted—Rep. Kansas Bd. Health, 1916, p. 133.
TERRA SILICEA PURIFICATA.
Scoville, W. L.: Infusorial earth, if used for filtering purposes,
must be watched closely. Even insoluble carbonates are detrimental,
and carbonates are frequently found.—J. Am. Pharm. Assoc. 1916,
v. 5, p. 539.
E’we, G. E.: Much of the kieselguhr on the market is unignited,
dark in color, and contains organic matter. For pharmaceutical
purposes, ignited kieseleuhr, nearly white in color and free from
organic matter, is preferable-——Proc. Pennsylvania Pharm. Assoc.
1916, p. 113.
Vanderkleed, C. E.: Much of the kieselguhr offered for pharma-
ceutical use contains organic matter, from which it should be freed
by ignition.—J. Am. Pharm. Assoc. 1916, v. 5, p. 540.
THEOBROMINZ SODIO-SALICYLAS,.
Lefeldt, M.: Attention is directed to the high (10 per cent) water
content permitted by the Ph. Germ. for this preparation. Five per
cent is considered to be ample.—Chem, Abstr, 1916, v. 10, p. 1773
from Pharm. Ztg. 1916, v. 61, p. 150.
THYMOL.
Holmes, E. M.: This may be obtained from the volatile oil of
Thymus vulgaris and “some other oils,” the names of which are not
mentioned.—Pharm. J. 1916, vy. 97, p. 485.
Dubose, A.: A consideration of various plants as sources from
which thymol may be obtained.—Chem. Abstr. 1916, v. 10, p. 251.
Norton, H.: On the sources and methods of obtaining thymol.—
Am. Perf. 1916, v. 11, p. 288.
Hood, Samuel C.: The commercial production of thymol from
horsemint (Jonarda punctata).—Bull. U. S. Dept. Agric. 1916,
No. 372, p. 1-12.
296
Anon.: The Technical Laboratory of the Department of Industries,
United Provinces of India, has issued a circular advocating the
manufacture of thymol in India, stating that it can be undertaken
without difficulty where the raw material is so plentiful, and that
very good samples have been obtained through experiments in the
industry conducted at the laboratory—Com. Rep. 1916, No. 37,
p. 610.
Anon.: In the new edition of the Finnish pharmacopeeia, the melt-
ing point of thymol is gven as 50° to 52° C.—Am. Perf. 1916, v. 11,”
p. 94. .
Editorial: Facts about the behavior of thymol in the body.
Thymol is an antiseptic comparable in many ways to phenol and
cresol, but is less soluble in water, and for this reason, it is supposed
to be absorbed with greater difficulty in the alimentary tract.—J.
Am. M. Assoc, 1916, v. 66, p. 746-747.
Schultz, W. H.: A study of the influence of various solvents on
the toxicity of thymol. Its parasiticidal powers were found to be
greatly diminished when it is dissolved in oi1].—Chem. Abstr. 1916,
v. 10, p. 2598.
THYMUS, N. F.
Anon.: A short note giving information relative to the cultiva-
tion of thyme in America.—N., A. R. D. J. 1916, v. 21, p. 704.
THYROIDEUM SICCUM.
Kendall, Edward: Recent advances in our knowledge of the active
constituent of the thyroid; its chemical nature and function.—Bos-
ton M. & S. J. 1916, v. 175, p. 557-562.
Graham, Allen: A study of the physiological activity of ade-
nomata of the thyroid gland in relation to the iodine content,
as evidenced by .feeding experiments on tadpoles.—J. Exper. M.
1916, v. 24, p. 345-36.
Roberts, J. G.: Determinations of the iodine content showed that
two lots of thyroid glands examined contained 0.20 and 0.18 per
cent, respectively.—Proe, Pennsylvania Pharm. Assoc. 1916, p. 118.
Tatum, A. L.: Notes on the use of Mallory’s connective tissue
stain as an indicator of thyroid colloid—J. Med. Research, 1916,
v. 30, p. 99-106,
Bube, 8. P.: In a discussion of the therapeutic application of
human thyroid, the author describes a method for preparing the
extract.—New York M. J. 1916, v. 104, p. 445-449.
Morris, Roger S.: A discussion of the probable toxic effects of |
prolonged administration of parathyroid gland.—J. Lab. & Clin.
Med. 1916, v. 1, p. 26-30.
297
__ Asher, Leon: Experimental data relating to the physiological ac-
tion of thyroid secretion and methods for the identification of the
same.—Deutsch. med. Wehnschr. 1916, vy. 42, p. 1028-1030,
Beebe, 8. P.: An enumeration of the therapeutic applications of
human thyroid extract—New York M. J. 1916, v. 104, p. 445-449,
TINCTURA.
Diekman, George C.: The number of tinctures now official in the
Pharmacopeia is 54, 10 having been omitted. The deleted tinctures
will hardly be missed, however, as most of them have found a place
in the National Formulary.—Pract. Drug. 1916, v. 84, No. 10, p. 24.
Scoville, W. L.: A disctission of the data obtained in experiments
to determine the relative stability of tinctures prepared from fluid
extracts and those prepared according to the U. 8S. P. methods.—
Midl. Bros. Drug. 1916, v. 50, p. 4-8.
_ Mossler, G., and Markus, F.: A description of a simple, rapid
method for the estimation of alcohol in tinctures. The method is
based on the determination of the critical solution temperature of a
mixture of benzene with the tincture to be examined. An abstract.—
Ann. Walsif. 1916, v. 9, p. 107.
Palme, Herman: A discussion of the relationship between specific
weight and the alcohol and extract content of tinctures. An equa-
tion is given for expressing this relation.—Svensk farm. Tidskr. 1916,
_V. 20, p. 373-377,
TINCTURA ACONITI.
Haskell, Charles C.: The quality of the tincture as indicated by
physiological and chemical assays. The results obtained in the
chemical assay are no indication of the activity of the preparation.—
Am. Druggist, 1916, v. 64, No. 4, p. 23-24.
Haskell, Charles C., and Thomas, H. B.: A comparison of the re-
sults obtained by the guinea pig and cat methods for the assay of
the tincture of aconite—Am. J. Pharm. 1916, v. 88, p. 3-7.
Haskell, Charles C.: An investigation of the effect of seasonal
variation on the resistance of guinea pigs to poisoning by tincture
of aconite—Am. J. Pharm. 1916, v. 88, p. 243-246.
Eskew, Harry L.: Of eight samples of tincture of aconite ex-
amined, seven were rejected.—Rep. Tennessee F'. & D. Dept. 1916,
p- 16. |
TINCTURA ARNICAE.
Frary, Guy G.: One sample of tincture of arnica examined was
rejected because it contained Jess alcohol than specified on the label._—
Rep. South Dakota F. & D. Com. 1916, No. 16, p. 190.
298
TINCTURA BELLADONNZE FOLIORUM.
Eskew, Harry L.: Of three samples of tincture of belladonna ex-
amined, one was rejected for being below standard.—Rep. te
I. & D. Dept. 1916, p. 16.
TINCTURA CARDAMOMI COMPOSITA.
Hill, C. A., and Umney, J. C.: In the preparation of the Ph. Brit.
compound tincture of cardamon, it 1s recommended that a 60 per
cent alcohol be used, and that the glycerin ratio be 1 in 20 in order to
avoid precipitation of the oils and to prevent gelatinization.—Brit.
& Col. Pharm. 1916, v. 69, p. 602.
TINCTURA CIMICIFUGA, N. F.
Tittle, Ella M.: A discussion of the physiological action of tinc-
ture of cimcifuga.—J. Am. Inst. Homoeop. 1916, v. 8, p. 1040-1042.
TINCTURA DIGITALIS.
Scholar, Abel: The author recommends preparing the tincture by
exhausting the drug with cold distilled water and adding sufficient
alcohol (90 per cent) to bring the alcoholic strength to 69 to 70
per cent.—Chem. & Drug. 1916, v. 88, p. 870.
TINCTURA FERRI CHLORIDI.
Frary, Guy G.: Two of three samples of tincture of ferric chloride
examined were rejected for being low in iron content.—Rep. South
Dakota F. & D. Com. 1916, No, 16, p. 150.
Todd, A. R.: Of two samples of tincture of ferric chloride ex-
amined, one was rejected.—Bull. Michigan D. & F. Dept. 1916, No.
244 947, p. 20.
Wood, H. C., jr.: Tincture of ferric chloride is valuable as an ex-
ternal remedy for checking hemorrhage, but it should not be admin-
istered internally as it is lable to cause constipation. Furthermore,
it is strongly irritant to mucous membranes and will often provoke
nausea.—J. Am. M. Assoc. 1916, v. 66, p. 1072.
TINCTURA GENTIANAE COMPOSITA.
Anon.: Notes on the preparation of compound tincture of gen-
tian.—N,. A. R. D. J. 1916, v. 22, p. 428.
TINCTURA IODI.
Diekman, George C.: The addition of 50 mils of distilled water to
each 1,000 mils of tincture of iodine as directed by the U. S. P. IX
should greatly facilitate the manufacture of this preparation. There
& 299
should be no further complaint concerning undissolved material and
subsequent shortage in iodine content. If the present directions are
followed, a standard product will result.—Pract. Drug. 1916, v. 34
No. 10, p. 24.
Anon.: Compressed tablets composed of iodine and_ potassium
iodide are being used in France for the extemporaneous preparation
,
_ of tincture of iodine—Boll. chim.-farm. 1915, v. 54, p. 170; see also
Chem. Abstr. 1916, v. 10, p. 2384.
Pisarzhevskii, L., and Tyel’nui, S.: In discussing electrolytic
iethods for obtaining solid iodine from solutions, the author refers
te the direct preparation of the tincture of iodine from alcoholic
_ solutions of iodides.—Chem. Abstr. 1916, vy. 10, p. 1731.
Gianturco, E.: A discussion of methods for the prevention of the
alteration of tincture of iodine intended for use in military surgery.
The use of 1 per cent of iodic acid is recommended as a preservative
in preference to potassium iodide. An abstract—U. S. Naval Med.
Bull. 1916, v. 10, p. 314-317.
Rho, F.: A discussion of the inconveniences due to the use of tinc-
ture of iodine in war times and suggestions for overcoming these
troubles.—Schweiz. Apoth.-Ztg. 1916, v. 54, p. 203-205.
Claret, A.: The addition of borax is recommended for the preser-
vation of tincture of iodine.—Boll. chim.-farm. 1915, v. 54, p. 584;
see also Chem. Abstr. 1916, v. 10, p. 2585.
Hugenholz: Tincture of iodine may be preserved unchanged by
storing in partially filled glass containers and exposing the latter to
light.—Boll. chim.-farm. 1915, v. 54, p. 584; see also Chem. Abstr.
1916, v. 10, p. 2885.
Crouzel, E.: The author recommends the use of an ethereal solu-
tion of iodine in place of the alcoholic tincture for the treatment of
wounds. Irritation due to the HI formed in the tincture is thus
eliminated.—Boll. chim.-farm. 1915, v. 54, p. 583; see also Chei.
Abstr. 1916, v. 10, p. 2384.
Schmerz, H.: As a substitute for tincture of iodine, a solution of 5
to 10 parts of tannin in alcohol is recommended.—Siidd. Apoth.-Ztg.
1916, v. 56, p. 191.
Hostmann, Jeannot: Of 20 samples of tincture of iodine examined,
4 were not of U. S. P. standard with respect to iodine content and
some of them did not contain the proper amount of potassium
iodide.—Proc. New Jersey Pharm. Assoc. 1916, p. 77.
Lea, E. J.: The samples of tincture of iodine examined were
slightly deficient in iodine, and two of them contained practically
no potassium iodide,—Bull. California Bd. Health, 1916, v. 12, p. 112.
Stinson, Ray: The percentage strengths of the samples of tincture
of iodine examined were below the official standard.—Proc. North
Dakota Pharm. Assoc., 1916, p. 112.
300
Table shoiting some of the analytical results reported for tineture of iod
Number of samples—
Reporters. Reierences. id
Examined.| Rejected. fe
57 45 | Proc. Maryland Pharm. Assoc. 1916, p. 84-94.
25 16 | Proc. Minnesota Pharm. Assoc. 191 6, p- 210. 4
39 18 | pul ome Bd. Health, 1916, v. 16, No. 3;
1 ee Rep: Avyoiiag F. & O. Com. 1916, v. 2, No.7,
Bamiard sho Bice e.ccm'se sss 27 14 | pai Travail Bd. Health, 1916, v. 19, P: Ae
}skew, Harry IU ARS aaoaeosor 2 1 | Rep. Tennessee F. & D. Dept. 1916, p.1
FroryyGny U/l ee | u 7 = Rep. South Dakota F. & D. Com. Iie, ‘No. 16, re:
147. Mi
J. vthgoe, Hermann C......... 191 25 | Bop. Massachusetts Bd. Health, 1916, ba Ra
Tice William (22s us- secon. 104 57 | Rep. New Jersey Dept. Health, 1916, rp. 72
od WAw eL. Bees sone aecene 28 59 | Bull. Michigan D. & F. Dept. 1916, 0. 214-247,
p. 20; Nos. 248-249, p. 10; Nos. 250-251, p. 16, q
Nos. 252-255, fo), URE
TINCTURA NUCIS VOMICZ.
Diekman, George C.: The change in the method of preparation of
tincture of nux vomica appears to be a desirable one. It is believed,
however, that the change in the alkaloidal standard will prove to be
unsatisfactory.—Pract. Drug. 1916, v. 34, No. 10, p. 24.
Todd, A. R.: Of four samples of tincture of nux vomica examined,
three were rejected for being low in alkaloidal content.—Bull. Michi-
gan D. & F. Dept. 1916, No. 244-947, p. 20.
TINCTURA OPII.
Diekman, George C.: The change in the morphine content of the
tinctures containing opium is due to the change in the morphine re-
quirements for opium. The difference, however, is more apparent
than real and makes very little difference, if any, in the therapeutic
value cf these preparations.—Pract. Drug. 1916, v. 34, No. 10, p. 24.
Anon.: Druggists can correct the strength of the tinctures of opium
which they have on hand by diluting them with 17 per cent of diluted
alcohol; that i is, 100 fluid ounces of the old tincture may be diluted
to 117 fluid ounces, with dilute aleohol, to make the U. S. P. IX tine-
ture.—Drug Topics, 1916, v. 31, No. 8, p. 21.
Editorial: Pharmacists should add to each 10 fluid ounces of old
tincture of opium in stock enough alcohol (46 per cent by volume)
to make 11.8 fluid ounces in order to make the preparation conform to
the U.S. P. IX requirements.—Virginia Pharmacist, 1916, v. 1, p. 45.
Bohrisch, P., and Kuerschner, F.: Fromme’s uscestee alumi
acetate method for the estimation of morphine in the tincture of
opium offers no material advantages.—Apoth.-Ztg. 1916, v. 31, p.
53-09 through Chem. Abstr. 1916, v. 10, p. 1251.
Ifesselbo, A.: A critical examination of the method of Dieterich
for the assay of tincture of opium as given in the Ph. Dan—Chem.
304
Abstr. 1916, v. 10, p. 951 from Arch. Pharm. og Chem. 1915, v. 22
-<—9
p. 18-26, 48-55, 74-84.
McGill, A.: Of 127 samples of tincture of opium examined, 31 were
below standard.—Bull. Lab. In]. Rev. Dept. Canada, 1916, No. 315,
p. 2.
“TINCTURA STROPHANTHI.
Anon.: Notes on the preparation of the tincture of strophanthus.—
PN. A. R. D. J. 1916, v. 22, p. 1184.
Anon.: Tincture of strophanthus is incompatible with water.
When it is mixed with water it undergoes hydrolysis with the forma-
tion of a toxic substance. An abstract—Pract. Drug. 1916, y. 34,
No. 6, p. 39.
Matcher, R. A.: A report on an investigation showing that the
emetic action of tincture of strophanthus is not due to the fixed oil
content.—J. Am. M. Assoc. 1916, v. 66, p. 1199.
Clampett, G. W.: Of six samples of tincture of strophanthus ex-
amined, the strophantin content in 100 cubic centimeters ranged from
0.07 to 0.400 per cent.—Proc. Texas Pharm. Assoc. 1916, p. 80.
TINCTURA VANILLA, N. F.
Dean, J. R., and Schlotterbeck, J. O.: A report of investigations
dealing with the preparation and properties of the extract of vanilla.
Special reference is made concerning the relation of the lead number
to the quality of the tincture —J. Ind. & Eng. Chem. 1916, v. 8, p.
607-614, 703-709.
Dox, Arthur W., and Plaisance, G. P.: An account of the deter-
mination of vanillin in vanilla extract by precipitation with thiobar-
bituric acid—Am. J. Pharm. 1916, v. 88, p. 481-484.
TINCTURA ZINGIBERIS.
Lea, E. J.: Many of the samples of tincture of ginger examined
were materially below the standard. Some contained less than 50
per cent of the required alcohol and very few even approximated the
standard.— Bull. California Bd. Health, 1916, v. 11, p. 648.
Table showing some of the analytical results reported for tincture of ginger.
Number of samples—
Reporters. =a References.
Examined.| Rejected.
SiN a adda tale ne> ain xe «cee |les se vese--> 3 | a California Bd. Health, 1916 ,v. 12, p. 112,
LE SE = Se ae 65 24 | Bull. Lab. In). Rev. Dept. Canada, 1916, No. 334,
ll 57 7 Bil, Nor Dakota Exper. Sta. F. Dept. 1916, v.
PRURAst A ase sagnccce st | 2 1 | Se tea D. & F. Dept. 1916, Nos. 244-247,
002
TINCTURZ HERBARUM RECENTUM.
Diekman, George C.: The deletion of the formula for tinctures of
fresh herbs meets with uniform approval. A mere useless formula —
can not be well imagined. The few who still dwell in the realms of
ancient pharmacy will find solace in the fact that this item is now
in the N. F.—Pract. Drug. 1916, v. 34, No. 10, p. 24.
TOXITABELLZ HYDRARGYRI CHLORIDI CORROSIVI.
Levy, Lewis Spencer: A description of a corrosive sublimate tablet
which can not be swallowed whole and which will produce emesi-
if broken and swallowed in part—J. Am. Pharm. Assoc. 1916, v. 5,
p. 1229-1231,
Walter: A discussion of the Ph. Germ. V and the Sasse methods
for the evaluation of mercuric chloride tablets. A method for deter-
mining the amount of mercuric chloride when it constitutes less than
20 per cent of the total ingredients is also described.—Chem. Zen-
tralbl. 1916, v. 87, part 2, p. 283.
Strickland, D. K.: Descriptions of methods for the determination
of mercuric chloride in tablets—J. Ind. & Eng. Chem. 1916, v. 8,
p- 253.
TRAGACANTHA.
Schneider, Albert: In the U. 8S. P. description of tragacanth no
mention is made of the fact that deepening of color (brownish) and
numerical increase in starch granules in the different commercial
tragacanths is in inverse ratio to the quality of this article-——Drug.
Cire. 1916, v. 60, p. 693.
Rusby, H. H.: Tragacanth several shades darker than that speci-
fied by the U. S. P. makes a perfectly white powder. Its use should
therefore be permitted.—J. Am. Pharm. Assoc. 1916, v. 5, p. 544.
E’we, G. E.: Experiments conducted in the Mulford Analytical
Laboratories show that, almost without exeeption, market samples
of ribbon tragacanth, when mixed with water, furnish a liquid which
is several times more viscous than the mixture of an equal weight
of powdered tragacanth with the same quantity of water—Proc.
Pennsylvania Pharm. Assoc. 1916, p. 118; see also Drug. Cire. 1917,
v. 61, No. 12, p. 25.
von Fellenberg: Descriptions of some of the properties of bassorin,
the water-soluble constituent of tragacanth. An abstract.—Drug.
Circ. 1916. v. 60, p. 398.
Gutbier, A., et al.: A report of an investigation of the colloidal
chemical properties of tragacanth extract.—Chem. Zentralbl. 1916,
v. 87, part 2, p. 46.
TRILLIUM, N. F.
Anon.: A short note giving information relative to the cultivation
of bethroot in America.—N. A. R. D. J. 1916, v. 21, p. 1275.
303
TRINITROPHENOL.
Castetes, J.: A description of a new reaction for the detection of
picric acid and a discussion of the application of the same in the
sxamination of urine and beer. Brom-dinitrophenol is first forme.
The test then depends upon the color reactions which result upon
the addition of ammonia or potassium cyanide.—J. pharm. et chin.
i¥L6, v. 18, p. 46-49.
_ Beon, A. A., and Ogilvie, J.: Experimental data showing that
_ pieric acid and picrates can be evenly titrated with ferric chloride.—
' Pharm. J. 1916, v. 97, p. 21-22.
Boon, A. A., and Ogilvie, J.: A description of a method for the
quantitative determination of picric acid by the use of a standard
solution of titanous chloride—Pharm. J. 1916, v. 97, p. 213-214.
Barral, Et.: A report of researches to determine the presence of
_ pieric acid in the case of simulated icterus—Ann. Falsif. 1916, v. 9,
_ p. 231-244.
Kohn-Abrest, E.: A report of investigations bearing on the de-
termination of picric acid in the urine and viscera.—Ann, Falsif.
1916, v. 9, p. 63-68.
Ydrac: A description of a method for the detection of picric acid
in the urine which depends on the formation of potassium isopur-
purate—Ann. chim. analyt. 1916, v. 21, p. 220.
Pecker, H.: A chemical study of picric acid poisoning.—J. pharm.
et chim. 1916, v. 14, p. 152-154.
Brown, T. F.: Notes on the use of picric acid in war surgery. A
report on the treatment of 3,000 cases.—Lancet, 1916, v. 2, p. 433.
TRITICUM.
Lilly, J. K.: Six lots of couch grass examined consisted of the
cut stems of the plant and only a small portion of rhizomes.—Oil,
Paint & Drug Rep. 1916, v. 90, No. 16, p. 46.
Roberts, J. G.: One lot of couch grass examined contained 6 per
cent of foreign roots.—Proc. Pennsylvania Pharm. Assoc. 1916, p.
Ait,
TROCHISCI.
Diekman, George C.: The reduction in the number of kinds of
troches from nine to five will not be criticized. In fact, if all had
been deleted there would have been but few mourners, especially as
the N. F. contains numerous formulas for this class of prepara-
tions.—Pract. Drug. 1916, v. 34, No. 10, p. 26.
ULMUS.
Anon.: A short note giving information relative to the produe-
tion and collection of slippery elm bark in America.—N. A, R. D. J.
1916, v. 21, p. 1056.
304
Schneider, Albert: In the U. S. P. description of ulmus bark, ne |
mention is made of the strikingly characteristic twin crystals—
Drug. Cire. 1916, v. 60, p. 693.
UNGUENTA.
Anon.: Notes on the preparation of ointments containing various
metals or their oxides in colloidal form.—Apoth.-Ztg. 1916, v. 31,
p- 19.
Maske, William, jr.: Notes on the incorporation of medicinal sub-
stances with ointment bases by means of volatile solvents.—Proc.
Washington Pharm. Assoc. 1916, p. 89-90.
Anon.: A number of formulas for the preparation of substitute
ointment bases, so-called war bases, is presented.—Pharm. Zentralh.
1916, v. 57, p. 96.
Cook, E. Fullerton: Notes on the sanitary dispensing of oint-
ments.—Proc, Pennsylvania Pharm. Assoc. 1916, p. 291-293.
UNGUENTUM AQUAE ROSAE.
Anon.: A discussion of a formula for the preparation of a stable
cold cream.—Svensk farm. Tidskr. 1916, v. 20, p. 81-82.
UNGUENTUM HYDRARGYRI.
Strickland, Donald K.: Laboratory notes on the quantitative de-
termination of mercury in various pharmaceutical preparations con-
taining the metal or its compounds.—J. Ind. & Eng. Chem. 1916, v.
8, p. 256-257.
UNGUENTUM HYDRARGYRI AMMONIATI.
Strickland, D. KX.: A description of an assay process for the deter-
minatiow of the mercury in ointment of ammoniated mercury.—J.
Ind. & Eng. Chem. 1916, v. 8, p. 253.
UNGUENTUM HYDRARGYRI DILUTUM.
Beringer, George M.: The strength of diluted mercurial ointment
has been reduced from 334 per cent to 30 per cent, in order to com-
ply with the International Protocol.—Am. Druggist, 1916, v. 64, No.
8, p. 28; see also George Diekman, Pract. Drug. 1916, v. 34, No. 10,
p. 20.
UNGUENTUM HYDRARGYRI NITRATIS.
Strickland, D. IKX.: A description of a method for the determina-
tion of mercury in the ointment of mercuric nitrate-—J. Ind. & Eng.
Chem. 1916, v. 8, p. 253.
3805
UNGUENTUM HYDRARGYRI OXIDI FLAVI.
Sjoestroem, F, W.: A paper discussing the preparation and assa y
of the ointment of yellow oxide of mercury. A method in which the
freshly prepared moist oxide (HgCl,-+-2NaOQH=Hg0+2NaCl-+-
HO) is first incorporated in lanolin is described. A volumetric
_ method for the determination of the oxide is also described.—Phari),
Ztg. 1915, v. 60, p. 544-545; see also Chem. Abstr. 1916, v. 10, p. 2276.
Strickland, Donald K.: A method for the quantitative determina-
tion of the mercury in the ointment of yellow oxide of mercury is
described.—J. Ind. & Eng. Chem. 1916, v. 8, p. 256-257.
UNGUENTUM HYDRARGYRI OXIDI RUBRI, N. F
Strickland, D. K.: A description of a method for the determina-
tion of mercury in the ointment of red mercuric oxide—J. Ind. &
Eng. Chem. 1916, v. 8, p. 253.
UNGUENTUM IODI.
Shimer, M. H.: For the extemporaneous preparation of iodine
ointment, the author recommends using a glycerite of iodine pre-
pared by mixing the iodine, potassiuin iodide, and glycerin in the
proportions given in the U. S. P.—Meyer Bros. Drug. 1916, v. 37,
p. 271.
Perusse, F. J.: The author expresses the opinion that the lard
directed to be used in the preparation of iodine ointment should be
replaced by a base which will not absorb iodine, such as a mixture
of lanolin and petrolatum.—Merck’s Rep. 1916, v. 25, p. T7.
Platt, W. R., and Smith, H. I.: In order to prepare a stainless
iodine ointment, that is, one in which all of the iodine is combined,
the authors suggest the use of a soft paraffin containing compara-
tively large amounts of unsaturated hydrocarbons.—Pharm. J. 1915,
v. 95, p. 544-546; see also Chem. Abstr. 1916, v. 10, p. 803.
Anon.: A method for the preparation of a nonstaining iodine oint-
ment consists of mixing powdered iodine with melted vaseline and
heating the mixture on a water Lath until it becomes homogeneous.—
Boll. chim.-farm. 1915, v. 54, p. 584; see also Chem. Abstr. 1916, v.
10, p. 2385.
UNGUENTUM IODOFORMI.
Ritchie, D. F.: The iodoform ointment of the new Brit. Ph. is
pharmaceutically unsound. The iodoform is decomposed by the
fatty acids developed in the lard.—Pharm, J. 1916, v. 41, p. 999.
110095°—19——20
306
UNGUENTUM RESORCINOLIS COMPOSITUM, N. F.
Breifeld: For the preparation of smooth ointments of resorcinol,
the use of a very fine powder is recommended. The same results
may be obtained by incorporating the resorcinol in the form of a
very concentrated ethereal solution.—Boll. chim.-farm. 1916, v. 55,
p. 296.
Anon.: Notes on the preparation of compound resorcinol ointment
call attention to the necessity for using petrolatum of U. S. P.
quality in order to avoid discoloration.—N. A. R. D. J. 1916, v. 23,
p. 193-194. .
Anon.: The compound resorcin ointment as made by different
pharmacists lacks uniformity owing to the fact that the oil of cade
used in its preparation is variable in composition, is often adulter-
ated, the latter being sometimes obtained from ordinary juniper
wood.—N. A. R. D. J. 1916, v. 21, p. 919.
Cook, E. Fullerton: The oil of cade formerly used in the prepara-
tion of compound resorcino] ointment has been replaced by rectified
oil of birch tar. By this means the darkening of the ointment upon
standing has been prevented.—Drug. Cire. 1916, v. 60, p. 548.
UNGUENTUM ZINCI OXIDI.
Austin, R. A.: A description of an easy method for preparing
oxide of zinc oimtment.—Proc. New York Pharm. Assoc. 1916,
p. 268.
Mueller, Ambrose: The U. S. P. ointment of zinc oxide can be
improved upon by substituting benzoinated white petrolatum for
benzoinated lard. By this means the tendency of the ointment to
become rancid is avoided.—Pract. Drug. 1916, v. 84, No. 4, p. 36.
Anon.: A report of a court case in England in which a low zine
oxide content of the ointment proved to be due to the settling of
the heavier particles of zinc oxide to the bottom of the container.—
Brit. Food J. 1916, v. 18, p. 389.
Anon.: Thirteen samples of zinc ointment examined were found
to be of U. S. P. quality.—Rep. Massachusetts Bd. Health, Feb
p- 450.
Casey, F. W.: Of five samples of zine oxide ointment candies
two were rejected.—Bull. Michigan D. & F. Dept. 1916, No. 252-255,
p. 19.
Stinson. Ray: Thirty-six of the 85 samples of ointment of zine
oxide examined were strictly U. S. P. Five of the samples con-
tained less than the required amount of zine oxide.—Proc. North
Dakota Pharm. Assoc. 1916, p. 111.
307
Terry, R. W.: The two samples of ointment of zine oxide ex-
_antned were of U.S. P. standard.—Proc. Ohio Pharm. Assoc. 1916,
p- 58.
VALERIANA.
Anon.: A short note giving information relative to the cultivation
of valerian in America.—N. A. R. D. J. 1916, v. 21, p. 804.
Holste, Arnold: A general discussion of valerian root and its
various preparations.—Deutsch. med. Wehnschr. 1916, v. 42, p.
599-601.
van der Wielen, P.: From experiments, it is concluded that the
development of the odor in valerian root is due to the action of a
ferment. If the enzyme is killed before drying the root, the odor
develops to a slight degree only. If an infusion of the root is
warmed with a little hydrochloric acid, the odor soon develops.—
Chem. & Drug. 1916, v. 88. p. 911.
Pilcher, Delzell, and Burman: A report of investigations to de-
termine the action of valerian on the excised uterus of the guinea
pig.—2J. Am. M. Assoc. 1916, v. 67, p..490-492.
VANILLA, N. F.
Anon.: An account of the production of vanilla in the French
colonies. It is estimated that these colonies furnish about two-
thirds of the world’s supply and that France consumes about one-
tenth of the total amount herself—Pharm. J. 1916, v. 97, p. 433.
Anon.: Information concerning the growing of vanilla in the
Seychelles.—Perf. & Ess. Oil Rec. 1916, v. 7, p. 17.
Lespinasse, A. J.: A short account of the cultivation of vanilla
in Mexico.—Mid]. Drug. 1916, v. 50, p. 22.
Costantin and Bois: Descriptions of the different botanical va-
rieties of vanilla—Compt. rend. acad. sc. 1916, v. 163, p. 466-470.
Rabak, Frank: A report of investigations to determine the effect
of curing on the aromatic constituents of vanilla beans.—J. Ind. &
Eng. Chem. 1916, v. 8, p. 815-821.
von Fellenberg, P.: A description of a colorimetric method for the
determination of vanillin in vanilla. The method is based on the
color which develops with concentrated sulphuric acid and isobutyl
alcohol. Analyst (The), 1916, v. 41, p. 280.
VANILLINUM.
Anon.: Remarks on the chemistry, manufacture, ‘and testing of
vanillin—Perf. & Ess. Oil Ree. wine v. 7, -p. 248-249.
Arny, H. V., and Ring, C. H.: A report on colorimetric tests for
vanillin.—J. Ind. & Eng. Chem. 1916, v. 8, p. 315-816,
308
Stinson, Ray: A sample of vanillin examined was found to con-
sist largely of salicylic acid. It began to soften at 70° C. and was
not completely melted at 95° C.—Proc. North Dakota Pharm. Assoc.
1916, p. 118.
VERATRINA.
Frankforter and Kritchevsky: Descriptions of two compoun:ls
formed as a result of the interaction of veratrine and chloral or
bromal in a carbon disulphide solution.—Chem. & Drug. 1916, v. 88,
p. 737.
Deelman, H. T.: A report of a study to determine the origin
of the veratrine curve obtained in poisoning of the muscles with
veratrine—Chem. Abstr. 1916, v. 10, p. 2875.
VERATRUM VIRIDE.
Anon.: A short note giving information relative to the produc-
tion and collection of hellebore root in America.—N. A. R. D. J.
1916, v. 21, p. 1227.
Patch, E. L.: Three lots of white hellebore examined yielded 0.9,
1.04, and 1.41 per cent of alkaloids, respectively. The ash content
of the same varied from 11 to 15 pe cent.—J. Am. Pharm. Assuve.
1916, v. 5, p. 539.
VIBURNUM OPULUS, N. F.
Anon.: A short note giving information relative to the produc-
tion and collection of cramp bark in America—N, A. R. D. J. 1916,
y. 21 yp. 1297.
Lilly, J. K.: Two lots offered as cramp bark consisted of the
bark of Acer spicatum.—Oil, Paint & Drug Rep. 1916, v. 90, No.
16, p. 46.
Pilcher, Delzell, and Burman: A report of investigations to de-
termine the action of cramp bark on the excised uterus of the guinea
pig.—J. Am. M. Assoc. 1916, v. 67, p. 490-492.
VIBURNUM PRUNIFOLIUM.
Anon.: A short note giving information relative to the production
ve collection of black hew bark in Ameri ica. —N. A. R. D. J. 1916,
PL op, AZ2T
ich i E. M.: Under the name of viburnum prunifolium, the
bark of V. Lentago, Linné, is official, as well as that of V. prumifo-
lium, but its distinctive characters are not given. There is no doubt
that the bark of V. Lentago is often mixed with that of V. pruni-
folium, and the U. 8. P. thus recognizes the fact—Pharm. J. 1916,
v. 97, p. 485.
309
Warren, L. E.: Analytical data relating to the composition of the
bark of the root of viburnum prunifolium are presented.—Rep.
Chem. Lab. Am. M. Assoc. 1916, p. 92-93, 98-103.
Pilcher, Delzell, and Burman: A report of investigations to de-
termine the action of black haw on the excised uterus of the guinea
pig.—2J. Am. M. Assoc. 1916, v. 67, p. 490-492.
VINA MEDICATA. ]
Sayre, L. E.: The members of the U. S. P. revision committee
appear to have understood section A, article 2 of the International
Protocol to mean that no potent medicament should be prepared in
the form cf a medicinal wine, and, hence, they have excluded from
the Pharmacopoeia all wines, including the much used wines of
colechicum and antimony.—Pharm. Era, 1916, v. '% p. 307-308.
Scoville, Wilbur L.: All wines have been deleted from the U. S.
P. They were the forerunners of the tinctures and maintained their
place for years because of the vinous odoi and fiavor. They have
no advantages over the corresponding tinctures and are gradually
passing into history.—Bull. Pharm. 1916, v. 30, p. 365.
Diekman, George C.: The deletion of wines from the U. S. P. is
stated to be one of the wise acts of the revison committee, as a more
useless and a less uniform class of galenicals can not well be imag-
ined.—Pract. Drug. 1916, v. 34, No. 10, p. 26.
VINUM CARNIS ET FERRI, N. F.
Anon.: Notes on the preparation of the wine of beef and iron.—
eee. J. 1916, -v. 22, p. 293.
Cook, E. Fullerton: The formula for the preparation of wine of
beef and iron has been reconstructed so that it now conforms to the
standards required by the Department of Agricuiture—Drug. Cire.
1916, v. 60, p. 543.
Mayer, Joseph L.: A report on the use of a colorimetric method
for the determination of iron in wine of beef and iron.—Am. Drug-
gist, 1916, v. 64, No. 5, p. 23-24.
Vanderkleed, C. E., and E’we, G. E.: Directions for the appli-
cation of the Wilfarth modification of the Kjeldahl method for the
determination of nitrogen and the assay for protein in beef extract
and wine of beef and iron.—J. Am. Pharm. Assov. 1916, v. 5, p. 716.
VINUM IPECACUANHA, N. F.
Jensen, Harold R.: A presentation of experimental data obtained
in the alkaloidal assay of wine of ipecac. The value of the various
methods employed or suggested is discussed in detail—Pharm. J.
1916, v. 96, p. 518-519.
o10
VINUM PEPSINI, N. F.
Messinger. M. L.: A formula for the preparation of wine of
pepsin is presented and discussed.—Drug. Cire. 1916, v. 60, p. 754.
VIRUS VACCINICUM.
Stewart, F. E.: An account of the preparation of smallpox vac-
cine.—Pharm. Era, 1916, v. 49, p. 465-466.
XANTHOXYLUM.
Anon.: A short note giving information relative to the production —
and collection of prickly ash bark in America.—N. A. R. D. J. 1916,
y. 21, p. 1058.
Holmes, E. M.: Xanthoxylum may be the dried bark of Xanthoxy-
lum Americanum, Miller, the northern prickly ash, or X. Clava-Her- —
culis, Linné, the southern prickly ash.—Pharm. J. 1916, v. 97, p. 485.
ZINCI BROMIDUM.
Guareschi, I.: In an article describing a number of the metallic
bromides, it is stated that zine bromide boils at 695° to 699° C. with-
out decomposition.—J. pharm. et chim. 1916, v. 13, p. 55.
ZINCI CARBONAS PRASCIPITATUS.
Hunebelle, E.: Swedish Patent No. 40,884. A method for obtain-
ing pure zinc carbonate. In brief, the zinc-containing material
is dissolved in hydrochloric acid and the impurities precipitated
with MgSO, and CaCO,. The zinc is finally precipitated with
MeCO,.—Chem. Abstr. 1916, v. 10, p. 2623.
De Coninck, W. O.: Some reactions of the carbonate of zine with
soluble salts are described.—Ann. chim. analyt. 1916, v. 21, p. 114;
see also Chem. Abstr. 1916, v. 10, p. 2175.
ZINCI CHLORIDUM.
Hunebelle, E.: U. S. Patent No. 1,201,586. A method for obtain-
ing pure zine chloride from zinc-containing materials is desecribed.—
Chem. Abstr. 1916, v. 10, p. 3142.
Bateman, E.: Tables and charts showing the relation between the
specific gravity of zinc chloride solutions and their concentrations are
presented.—Chem. Abstr. 1916, v. 10, p. 2518 from Wood Preserving,
1916, v. 3, p. 54-56.
ZINCI OXIDUM.
Aself, W.: British Patent No, 23,826. Zine oxide is prepared by
precipitation from a solution of an alkali zincate. Precipitation is
brought about by the addition of a solution of one or more salts inert
to the alkali.—Chem. Abstr. 1916, v. 10, p. 1582.
-_—
311
De Stuckle, H. W.: Swedish Patent No. 40,693. Pure zinc oxide is
_ obtained by treating solutions of purified zine salts with (NH,),SO,
in the presence of NH,OH or NH,CO, and subsequently heating to
incandescence the ZnSO, formed.—Chem. Abstr. 1916, v. 10, p. 2346.
Scoville, W. L.: Considerable difficulty has been experienced in
securing zinc oxide which will meet the U.S. P. test for heavy metals.
Most of the samples gave only a slight test, but they were not
U.S. P.—J. Am. Pharm. Assoc. 1916, v. 5, p. 545.
E’we, G. E.: One lot of zinc oxide examined contained chloride in
excess of the U. S. P. limits; however, the chloride was easily re-
moved by washing with water.—Proc. Pennsylvania Pharm. Assoc.
1916, p. 118.
Frary, Guy G.: Six of the 25 samples of zinc oxide examined were
rejected because they were not of U. S. P. quality. The samples
rejected gave a test for sulphate, heavy metals, and lead—Rep. South
Dakota F. & D. Com. 1916, No. 16, p. 145-147.
Roberts, J. G.: Two lots of zinc oxide examined showed the pres-
ence of an excess of heavy metals and chloride.—Proc. Pennsylvania
Pharm. Assoc. 1916, p. 118.
ZINCI-SULPHAS.
Durant, H. T.: British Patent No. 21,737. A method for obtaining
zine sulphate free from iron salts and See is described.—Chem.
Abstr. 1916, v. 10, p. 1257.
Araki, S.: U. S. Patent No. 1,185,757. A method of obtaining
zine sulphate by the extraction of zinc ores with NaHSO, solution is
described.—Chem. Abstr. 1916, v. 10, p. 2029.
E’we, G. E.: One lot of zine sulphate examined was acid to litmus,
The free acid was equivalent to 0.2 per cent H,SO,.—Proc. Pennsyl-
vania Pharm. Assoc. 1918, p. 118.
ZINCUM.
Baxter, G. P., and Grose, M. R.: The atomic weight of zinc as
indicated by the electrolytic determination of zinc in zine bromide
is 65.388.—J. Am. Chem. Soc. 1916, v. 38, p. 368-873.
Myers, Chester N.: Tests made by the author showed that com-
mercial samples of zinc labeled as being free from arsenic contained
from 1 to 10 parts of arsenic per million—Public Health Rep. 1916,
v. 31, p. 2754-2755. .
ZINGIBER.
Memminger, Lucien: A consular report describing the ginger in-
dustry of Southern India.—Com. Rep. 1916, No. 220, p. 1068-L06»).
Anon.: Remarks on the history and dispersion of ginger.—Pert. &
fess. Oil Rec. 1916, v. 7, p. 106-108.
312
Folpmers, T.: Data obtained in the determination of moisture in.
ginger by the direct and indirect methods are given.—Chem. Week-
blad, 1916, v. 18, p. 14-16.
Brooks, Benjamin T.: A report of researches dealing with the iso--
lation of zingiberol, a new sesquiterpene alcohol occurring in the
essential oil of ginger—J. Am. Chem. Soc. 1916, v. 38, p. 430-432.
Frary, Guy G.: All of the samples of powdered ginger examined —
were passed.—Rep. South Dakota F. & D. Com. 1916, No. 16, p. 135.
Sayre, L. E.: A sample of Jamaica ginger examined was found to
_ be adulterated.—Bull. Kansas Bd. Health. 1916, p- 9.
-non.: The oleoresin content of one sample of African ginger
assayed was above standard. The oleoresin content of three samples
cf Jamaica ginger assayed was above standard.—Proc. Pennsylvania
Pharm. Assoc. 1916, p. 119.
Vanderkleed, C. E.: The two samples of African ginger examined
yielded 7.99 and 8. 90 per cent of oleoresin; one sample of Jamaica
ginger yielded 3.93 per cent.—J. Am. Pharm. Assoc. 1916, v. 5, p. 539.
HYGIENIC LABORATORY BULLETINS OF THE PUBLIC HEALTH SERVICE.
The Hygienic Laboratory was established in New York, at the Marine Hos-
pital on Staten Island, August, 1887. It was transferred to Washington, with
quarters in the Butler Building, June 11, 1891, and a new laboratory building,
located in Washington, was authorized by act of Congress March 8, 1901.
Of the bulletins published by the laboratory since its establishment, copies of
the following are available for distribution and may be obtained without cost
by applying to the Surgeon General, United States Public Health Service,
Washington, D. C.
No. 2.—Formalin disinfection of baggage without apparatus. By M. J.
Rosenau.
No. 48.—The standardization of tetanus antitoxin (an American unit estab-
lished under authority of the act of July 1, 1902). By M. J. Rosenau and John
F. Anderson.
No. 44.—Report No. 2 on the origin and prevalence of typhoid fever in the
District of Columbia, 1907.—By M. J. Rosenau, L. L. Lumsden, and Joseph H.
Kastle.
No. 45.—Further studies upon anaphylaxis. By M. J. Rosenau and Jolm F,
Anderson.
No. 46.—Hepatozoon perniciosum (n. g., n. sp.) ; a hemogregarine pathogenic
for white rats; with a description of the sexual cycle in the intermediate host,
a mite (lelaps echidnimus). By W. W. Miller. u
No. 50.—Further studies upon the phenomenon of anaphylaxis. By M. J.
Rosenau and John F. Anderson.
No. 51.—Chemical tests for blood. By Joseph H. Kastle.
No. 52.—Report No. 3 on the origin and prevalence of typhoid fever in the
District of Columbia (1908). By M. J. Rosenau, Leslie L. Lumsden, and Joseph
H. Kastle.
No. 53.—The influence of certain drugs upon the toxicity of acetanilide and
antipyrine. By Worth Hale.
No. 55.—Quantitative pharmacological studies; adrenalin and adrenalin-like
bodies. By W. H. Schultz.
No. 59.—The oxidases and other oxygen catalysts concerned in biological
oxidations. By Joseph H. Kastle.
No. 61.—Quantitative pharmacological studies ; Relative physiological activity
of some commercial solutions of epinephrin. By W. H. Schultz.
No. 65.—Facts and problems of rabies. By A. M. Stimson.
No. 66.—I. The influence of age and temperature on the potency of diphtheria
antitoxin. By John F. Anderson. IL. An organism (Pseudonomas protca)
isolated from water, agglutinated by the serum of typhoid-fever patients. By
W. H. Frost. III. Some considerations on colorimetry, and a new colorimeter.
By Norman Roberts. IV. A gas generator in four forms, for laboratory sud
technical use. By Norman Roberts.
No. 68.—The bleaching of flour and the effect of nitrites on certain medicinal
substances. By Worth Hale.
(313)
314
No. 73.—The effect of a number of derivatives of choline and analogous com-
pounds on the blood pressure. By Reid Hunt and R. de M. Taveau. ;
No. 75.—Digest of comments on the Pharmacopeia of the United States of
America (eighth decennial revision) and the National Formulary (third edi- —
tion) for the calendar year ending December 31, 1908. By Murray Galt Mctter
and Martin I. Wilbert.
No. 76.—The physiological standardization of ergot. By Charles Wallis
Edmunds and Worth Hale.
No. 78.—Report No. 4 on the origin and prevalence of typhoid fever in the
District of Columbia (1909). By L. L. Lumsden and John F. Anderson. (In-
cluding articles contributed by Thomas B. MecClintic and Wade H. Frost.) .
No. 81.—Tissue proliferation in plasma medium. By John Sundwall.
No. 84.—Digest of comments on the Pharmacopeia of the United States of
America (eighth decennial revision) and the National Formulary (third edi-
tion) for the calendar year ending December 31, 1910. By Murray Galt Motter
and Martin I. Wilbert.
No. 85.—Index-catalogue of medical and veterinary zoology. Subjects: Ces-
toda and cestodaria. By Ch. Wardell Stiles and Albert Hassall.
No. 86.—Studies on typhus. By John F. Anderson and Joseph Goldberger.
No. 87.—Digest of comments on the Pharmacopeeia of the United States of
America (eighth decennial revision) and on the National Formulary (third
edition) for the calendar year ending December 31, 1911. By Murray Galt
Motter and Martin I. Wilbert.
No. 89.—Sewage pollution of interstate and international waters with special
reference to the spread of typhoid fever. VI. The Missouri River from Sioux
City to its mouth. By Allan J. McLaughlin.
No. 90.—Epidemiologic studies of acute anterior poliomyelitis. I. Poliomye-
litis in Iowa, 1910. II. Poliomyelitis in Cincinnati, Ohio, 1911. III. Poliomye-
litis in Buffalo and Batavia, N. Y., 1912. By Wade H. Frost.
No. 91.—I. The cause of death from subjural injections of antimeningitis
serum. By Worth Hale. II. Some new cholera selective media. By Joseph
Goldberger.
No. 94.—I. Collected studies on the insect transmission of T'rypanosoma
evansi. By M. Bruin Mitzmain. II. Summary of experiments in the transmis-
sion of anthrax by biting flies. By M. Bruin Mitzmain.
No. 95.—Laboratory studies on tetanus. By Edward Francis.
No. 96.—1. Report of investigation of coastal waters in the vicinity of Gulf-
port and Biloxi, Miss., with special reference to the pollution of shellfish. By
R. H. Creel. 2. A comparison of methods for the determination of oxygen in
waters in presence of nitrite. By Elias Elvove. 38. Some new compounds of
the choline type. III. Including preparatiom of monoacetate of a, B dioxy-B-
methyl butane. By G. A.-Menge. 4. The detection of white phosphorus in
matches. By Earle B. Phelps. 5
5. The chemical composition of rubber in nurs-
ing nipples and in some rubber toys. By Earle B. Phelps and Albert F. Steven-
son. 6. The analysis of thymol capsules. By Atherton Seidell. 7. Seasonal
variation in the composition of the thyroid gland. By Atherton Seidell and
Frederic Fenger. 8. Note on a new apparatus for use with the Winkler method
for dissolved oxygen in water. By Hyman L. Shoub. 9. The pharmacological
action of some serum preservatives. By Carl Voegtlin.
No. 97.—1. Some further siphonaptera. 2. A further report on the identifica-
tion of some siphonaptern from the Philippine Islands. 38. The taxonomie
value of the copulatory organs of the females in the order of siphonaptera:
sy Carroll Fox,
:
315
No, 100.—Pituitary standardization; a comparison of the physiological ac-
tivity of some commercial pituitary preparations. By George B. Roth. 2.
Examination of drinking water on railroad trains. By Richard H. Creel. 3.
Variation in the epinephrine content of suprarenal glands. By Atherton Seidel
and Frederic Fenger.
No. 102.—I. Digitalis standardization. The physiological valuation of fat-free
digitalis and commercial digitalin. By George B. Roth. II, Preliminary obser-
vations on metabolism in pellagra. By Andrew Hunter, Maurice H. Givens.
and Robert C. Lewis.
No. 103.—I. Chemical changes in the central nervous system as a result of
restricted vegetable diet. By Mathilde L. Koch and Carl Voegtlin. II. Chemical
changes in the central nervous system in pellagra. By Mathilde L. Koch and
Cari Voegtlin.
No. 104.—Investigation of the pollution and sanitary conditions of the Poto-
mac watershed ; with special reference to self-purification and sanitary condi-
tion of shellfish in the lower Potomac River. By Hugh S. Cumming. With
plankton studies by W. C. Purdy and hydrographic studies by Homer P. Ritter,
No. 106.—Studies in Pellagra. I. Tissue alteration in malnutrition and
pellagra. By John Sundwall. IJ. Cultivation experiments with the blood and
spinal fluid of pellagrins. By Edward Francis. III. Further attempts to
transmit pellagra to monkeys. By Edward Francis.
No. 108.—Experimental studies with muscicides and other fly-destroying
agencies. By Earle B. Phelps and A. F. Stevenson.
No. 109.—I. Pituitary standardization, 2: The relative value of infundibular
extracts made from different species of mammals and a comparison of their
physiological activity with that of certain commercial preparations. By
George B. Roth. II. Pharmacological studies with cocaine and novocaine; a
comparative investigation of these substances in intact animals and on isolated
organs. By George B. Roth.
No. 110.—I. The standardization of antityphoid vaccine. By George W.
McCoy. II. A colorimetric method for the estimation of the cresol or phenol
preservative in serums. By Elias Elvove. III. Toxicity of certain preserva-
tives used in serums, viruses, and vaccines. By James P. Leake and Hugh B.
Corbitt. IV. Observations on the significance of antisheep amboceptor in
human serum, with reference to complement fixation test for syphilis. By
Mather H. Neill.
No. 111.—I. The pathology and pathogenesis of myelitis. By N. E. Wayson.
II. Experimental poliomyelitis. By J. P. Leake. III. Attempts to induce
poliomyelitis in small laboratory animals. By A. M. Stimson, IV. Report on
attempts to cultivate the virus of poliomyelitis. By N. BE. Wayson,
No. 112.—I. Phenols as preservatives of antipneumococciec serum; a pharma-
cological study. By Carl Voegtlin. II. The nature of contaminations of bio-
logical products. By I. A. Bengtson. IV. Studies in preservatives of bio-
logical products: The effects of certain substances on organisms found in bio-
logical products. By M. H. Neill. IV. The effect of ether on tetanus spores
and on certain other microorganisms. By H. B. Corbitt.
No. 113.—I. An experimental investigation of the toxicity of certain organic
arsenic compounds. By George B. Roth. Il. On the toxicity of emetine hydre-
chloride, with special reference to the comparative toxicity of various market
preparations. By Gleason C. Lake,
No. 114.—Index catalogue of medical and veterinary zoology. Subject:
Roundworms. By Ch. Wardell Stiles and Albert Hassall.
316
No. 115.—I. Notes on the detection of B. tetani. By G. W. McCoy and Ida A.
Bengtson. II. The standardization of pituitary extracts. By Reynold A.
Spaeth.
No. 116. The influence of vitamines on the course of pellagra. By Carl
Voegtlin, M. H. Neill, and Andrew Hunter. II. The chemical composition of
the blood of pellagrins. By Robert C. Lewis. III. The amino acid fractions
and hippurie acid in the urine of pellagrins. By John R. Murlin. IV. The o2-
eurrence of pellagra in nursing infants, with observations on the chemical —
composition of the human milk from pellagrous mothers. By Carl Voegtlin
end R. H. Harries.
No. 117. Filariasis in southern United States. By Edward Francis.
No. 118.—Digest of comments on the Pharmacopeia of the United States of
America and on the National Formulary for the calendar year ending Decem-
ber 31, 1915. By A. G. Du Mez,
No. 119. Digest of comments on the Pharmacopceia of the United States of
America and on the National Formulary for the calendar year ending Decem- —
ber 31, 1916. By A. G. Du Mez.
In citing these bulletins bibliographers and authors are requested to nace
the following abbreviations: Bull. No. yg. Lab., Wash., pp. —.
The service will enter into exchange of publications with medical and scientific
organizations, societies, laboratories, journals, and authors. ALL APPLICATIONS FOR
THESE PUBLICATIONS SHOULD BE ADDRESSED To THE “ Surgeon General, U. S.
Publie Health Service, Washington, D. C.”
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